#ID	gene_name	control-1_FPKM	control-1_count	control-2_FPKM	control-2_count	control-3_FPKM	control-3_count	pLV-1_FPKM	pLV-1_count	pLV-2_FPKM	pLV-2_count	pLV-3_FPKM	pLV-3_count	control-1_vs_pLV-1_EBSeq_FDR	control-1_vs_pLV-1_EBSeq_log2FC	control-1_vs_pLV-1_EBSeq_(FDR_0.01_FC_2)_regulated	control-2_vs_pLV-2_EBSeq_FDR	control-2_vs_pLV-2_EBSeq_log2FC	control-2_vs_pLV-2_EBSeq_(FDR_0.01_FC_2)_regulated	control-3_vs_pLV-3_EBSeq_FDR	control-3_vs_pLV-3_EBSeq_log2FC	control-3_vs_pLV-3_EBSeq_(FDR_0.01_FC_2)_regulated	control_vs_pLV_EBSeq_FDR	control_vs_pLV_EBSeq_log2FC	control_vs_pLV_EBSeq_(FDR_0.01_FC_2)_regulated	COG_class	COG_class_annotation	GO_annotation	KEGG_annotation	KEGG_pathway_annotation	KOG_class	KOG_class_annotation	Pfam_annotation	Swiss_Prot_annotation	eggNOG_class	eggNOG_class_annotation	NR_annotation
ENSG00000000003(TSPAN6)	--	36.410026	1024	33.08554318	944	36.36626152	1019	42.12	1223	42.05794155	1197	41.45971	1186	0.952190529	0.225067117	normal	0.884437939	0.320680682	normal	0.957138714	0.210368869	normal	0.163865794	0.250500201	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17295|0|pps:100985171|TSPAN6; tetraspanin 6; K17295 tetraspanin-6 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-6 GN=TSPAN6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetraspanin-6 [Tupaia chinensis]
ENSG00000000419(DPM1)	--	46.64368215	733	42.90437627	680	46.7892886	733	48.91388601	782	45.1842751	705	37.07349833	583	0.974669659	0.062396514	normal	0.9743167	0.030595129	normal	0.847843571	-0.337825452	normal	0.794101537	-0.073987289	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K00721|1.25105e-163|pon:100447907|DPM1; dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; K00721 dolichol-phosphate mannosyltransferase [EC:2.4.1.83] (A)"	N-Glycan biosynthesis (ko00510)	[R]	General function prediction only	Glycosyl transferase family 2;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2	Dolichol-phosphate mannosyltransferase subunit 1 GN=DPM1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	hypothetical protein PANDA_000790 [Ailuropoda melanoleuca]
ENSG00000000457(SCYL3)	--	2.707551637	231	2.098309004	180	2.100115155	163	3.10200009	240	2.3771061	197	2.639839857	221	0.966809998	0.024151695	normal	0.961412769	0.107905407	normal	0.79248601	0.427464504	normal	0.64117598	0.175170001	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K17542|0|pon:100439771|SCYL3; SCY1-like 3 (S. cerevisiae); K17542 SCY1-like protein 3 (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Protein-associating with the carboxyl-terminal domain of ezrin GN=SCYL3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein-associating with the carboxyl-terminal domain of ezrin isoform X1 [Galeopterus variegatus] 
ENSG00000000460(C1orf112)	--	8.865416588	346	9.33408586	341	12.00554069	415	10.7720276	417	8.11812364	318	10.50840627	378	0.932253306	0.237481435	normal	0.960364957	-0.121612881	normal	0.959447094	-0.14247233	normal	0.990595451	-0.006931874	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4487)	Uncharacterized protein C1orf112 GN=C1orf112 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf112 homolog [Galeopterus variegatus]
ENSG00000000971(CFH)	--	10.57440972	577	12.45844053	715	8.688636115	491	17.0393185	1118	25.1292753	1673	24.86189948	1739	1.64E-05	0.921651536	normal	4.58E-10	1.203283338	up	0	1.813005263	up	0.000109592	1.324840991	up	--	--	--	"K04004|0|hsa:3075|CFH, AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS; complement factor H (EC:4.2.1.2); K04004 complement factor H (A)"	Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150)	--	--	Sushi domain (SCR repeat)	Complement factor H (Precursor) GN=CFH OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: complement factor H isoform X3 [Oryctolagus cuniculus]
ENSG00000001036(FUCA2)	--	43.77688	1729	47.22924	1920	47.79277	1843	46.00405	1846	41.40389	1656	44.50339	1728	0.984649985	0.06357774	normal	0.959503486	-0.234630988	normal	0.982715981	-0.101158554	normal	0.687987147	-0.091953298	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: alpha-L-fucosidase activity (GO:0004560);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K01206|0|hsa:2519|FUCA2, dJ20N2.5; fucosidase, alpha-L- 2, plasma (EC:3.2.1.51); K01206 alpha-L-fucosidase [EC:3.2.1.51] (A)"	Other glycan degradation (ko00511)	[G]	Carbohydrate transport and metabolism	Alpha-L-fucosidase	Plasma alpha-L-fucosidase (Precursor) GN=FUCA2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: plasma alpha-L-fucosidase [Tupaia chinensis]
ENSG00000001084(GCLC)	--	60.84872979	3856	77.91367001	5053	68.36904104	4375	39.2454779	2491	38.64660955	2290	46.36959286	2828	0.014427393	-0.660881801	normal	4.25E-10	-1.162688152	down	0.027806469	-0.637516012	normal	6.28E-06	-0.824850855	normal	--	--	Molecular Function: glutamate-cysteine ligase activity (GO:0004357);; Biological Process: glutathione biosynthetic process (GO:0006750);; 	"K11204|0|ptr:742732|GCLC; glutamate-cysteine ligase, catalytic subunit; K11204 glutamate--cysteine ligase catalytic subunit [EC:6.3.2.2] (A)"	Glutathione metabolism (ko00480)	[H]	Coenzyme transport and metabolism	Glutamate-cysteine ligase	Glutamate--cysteine ligase catalytic subunit GN=GCLC OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: glutamate--cysteine ligase catalytic subunit [Galeopterus variegatus]
ENSG00000001167(NFYA)	--	8.18293512	608	9.42410347	689	8.106933268	614	8.767211004	711	9.042528691	729	8.605197006	606	0.952896239	0.194491148	normal	0.97346714	0.059860535	normal	0.97362725	-0.027145005	normal	0.786374162	0.076751151	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K08064|5.88346e-95|ggo:101153000|NFYA; nuclear transcription factor Y subunit alpha; K08064 nuclear transcription factor Y, alpha (A)"	Antigen processing and presentation (ko04612);; Tuberculosis (ko05152)	[K]	Transcription	CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B	Nuclear transcription factor Y subunit alpha GN=NFYA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear transcription factor Y subunit alpha isoform X2 [Myotis lucifugus]
ENSG00000001460(STPG1)	--	3.1342	151	3.900861337	166	4.14164938	182	4.424130366	213	2.61495984	125	4.773593	198	0.744902592	0.461502097	normal	0.836394136	-0.426191187	normal	0.962259576	0.112375081	normal	0.878733152	0.081761698	normal	--	--	--	--	--	--	--	Sperm-tail PG-rich repeat	O(6)-methylguanine-induced apoptosis 2 GN=STPG1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: O(6)-methylguanine-induced apoptosis 2 [Galeopterus variegatus]
ENSG00000001461(NIPAL3)	--	8.024034147	564	7.608881	523	7.355433001	567	9.074590002	769	8.385552179	534	9.605613	659	0.673514748	0.41548353	normal	0.971605591	0.008577692	normal	0.947731808	0.208122946	normal	0.368620768	0.224622075	normal	--	--	Molecular Function: magnesium ion transmembrane transporter activity (GO:0015095);; Biological Process: magnesium ion transport (GO:0015693);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Magnesium transporter NIPA	NIPA-like protein 3 GN=NIPAL3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: NIPA-like protein 3 [Elephantulus edwardii]
ENSG00000001497(LAS1L)	--	40.45587	1885	36.677004	1764	42.21783	2024	39.814659	1960	38.848753	1848	34.13490091	1570	0.986335084	0.025436535	normal	0.984973525	0.045649402	normal	0.81673224	-0.374417642	normal	0.65947998	-0.098666268	normal	--	--	--	K16912|0|mcf:102141577|LAS1L; LAS1-like (S. cerevisiae); K16912 ribosomal biogenesis protein LAS1 (A)	--	[R]	General function prediction only	Las1-like	Ribosomal biogenesis protein LAS1L GN=LAS1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ribosomal biogenesis protein LAS1L [Odobenus rosmarus divergens]
ENSG00000001561(ENPP4)	--	4.912359111	304	4.578658581	282	3.990310934	240	2.614331126	164	2.133016221	132	2.480577165	154	0.001349565	-0.914807121	normal	4.36E-05	-1.107686795	down	0.221810913	-0.643293179	normal	0.000208032	-0.898022348	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K18424|0|hsa:22875|ENPP4, NPP4; ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) (EC:3.6.1.29); K18424 ectonucleotide pyrophosphatase/phosphodiesterase family member 4 [EC:3.6.1.29] (A)"	Purine metabolism (ko00230)	[R]	General function prediction only	Type I phosphodiesterase / nucleotide pyrophosphatase;; Sulfatase	Bis(5'-adenosyl)-triphosphatase ENPP4 (Precursor) GN=ENPP4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: bis(5'-adenosyl)-triphosphatase ENPP4 [Galeopterus variegatus]
ENSG00000001617(SEMA3F)	--	6.910347373	434	4.119798431	285	5.380822599	316	1.067880511	60	1.441238901	101	1.197828777	79	0	-2.853672765	down	3.25E-09	-1.504012118	down	5.55E-16	-1.987725354	down	1.14E-08	-2.128922657	down	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06840|0|hsa:6405|SEMA3F, SEMA-IV, SEMA4, SEMAK; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; K06840 semaphorin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain	Semaphorin-3F (Precursor) GN=SEMA3F OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: semaphorin-3F isoform X1 [Felis catus]
ENSG00000001626(CFTR)	--	0	0	0.018413159	2	0.0182206	1	0.0181293	2	0.400292186	14	0.11773	13	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05031|0|hsa:1080|CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49); K05031 cystic fibrosis transmembrane conductance regulator [EC:3.6.3.49] (A)"	ABC transporters (ko02010);; cAMP signaling pathway (ko04024);; AMPK signaling pathway (ko04152);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Vibrio cholerae infection (ko05110)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Cystic fibrosis TM conductance regulator (CFTR), regulator domain;; ABC transporter transmembrane region;; ABC transporter;; AAA domain;; P-loop containing region of AAA domain;; AAA ATPase domain;; Type II/IV secretion system protein;; Miro-like protein;; Domain of unknown function DUF87"	Cystic fibrosis transmembrane conductance regulator GN=CFTR OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	cystic fibrosis transmembrane conductance regulator [Equus caballus] 
ENSG00000001629(ANKIB1)	--	18.84596	2144	19.58424	2220	19.4703	2182	19.73712	2252	19.05571	2164	19.28725	2193	0.987327938	0.04004166	normal	0.986524383	-0.058245546	normal	0.98769025	-0.001036016	normal	0.985016047	-0.007468537	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K11967|0|hsa:54467|ANKIB1; ankyrin repeat and IBR domain containing 1; K11967 ankyrin repeat and IBR domain-containing protein 1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat and IBR domain-containing protein 1 GN=ANKIB1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ankyrin repeat and IBR domain-containing protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000001630(CYP51A1)	--	64.22306726	3250	71.2433136	3624	74.18155763	3717	35.22194431	1808	39.08621847	1910	69.7177786	3455	2.02E-05	-0.876313307	normal	2.88E-06	-0.944884002	normal	0.988883417	-0.113696427	normal	0.116917383	-0.581301898	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K05917|0|hsa:1595|CYP51A1, CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1; cytochrome P450, family 51, subfamily A, polypeptide 1 (EC:1.14.13.70); K05917 sterol 14-demethylase [EC:1.14.13.70] (A)"	Steroid biosynthesis (ko00100)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Lanosterol 14-alpha demethylase GN=CYP51A1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: leucine-rich repeat and death domain-containing protein 1-like isoform 2 [Odobenus rosmarus divergens]
ENSG00000001631(KRIT1)	--	12.71864835	673	17.23390406	793	15.82680649	820	10.60884852	566	14.08293503	698	14.28039199	784	0.90956444	-0.279938755	normal	0.951334155	-0.205103137	normal	0.974853405	-0.07292414	normal	0.493909195	-0.178630808	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17705|0|ptr:463528|KRIT1; KRIT1, ankyrin repeat containing; K17705 Krev interaction trapped protein 1 (A)"	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	FERM central domain;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Krev interaction trapped protein 1 GN=KRIT1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: krev interaction trapped protein 1 isoform 2 [Ceratotherium simum simum]
ENSG00000002016(RAD52)	--	5.494360078	213	4.5217009	191	6.24648514	201	4.698469524	189	7.283763911	230	9.235253383	291	0.94832971	-0.201753295	normal	0.934102292	0.244865812	normal	0.498574769	0.52224873	normal	0.549439066	0.211008614	normal	[L]	"Replication, recombination and repair"	Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; 	K10873|0|hsa:5893|RAD52; RAD52 homolog (S. cerevisiae); K10873 DNA repair and recombination protein RAD52 (A)	Homologous recombination (ko03440)	[L]	"Replication, recombination and repair"	Rad52/22 family double-strand break repair protein	DNA repair protein RAD52 homolog GN=RAD52 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein RAD52 homolog [Ceratotherium simum simum]
ENSG00000002330(BAD)	--	40.118599	592	34.410469	519	46.39547	702	43.612628	626	47.41437	670	36.777203	532	0.972743308	0.049608011	normal	0.838132888	0.346110271	normal	0.701363203	-0.407324901	normal	0.985435375	-0.009235261	normal	--	--	Biological Process: apoptotic process (GO:0006915);; 	K02158|3.32443e-103|pps:100988665|BAD; BCL2-associated agonist of cell death; K02158 BCL2-antagonist of cell death (A)	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Thyroid hormone signaling pathway (ko04919);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223)	--	--	"Pro-apoptotic Bcl-2 protein, BAD"	Bcl2-associated agonist of cell death GN=BAD OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: bcl2 antagonist of cell death [Galeopterus variegatus]
ENSG00000002549(LAP3)	--	19.456853	770	19.67653806	798	17.83868	724	19.90652612	777	18.92492392	705	16.012773	629	0.976424604	-0.017740872	normal	0.953132309	-0.199788916	normal	0.948235355	-0.210748419	normal	0.55303736	-0.140654652	normal	[E]	Amino acid transport and metabolism	Molecular Function: aminopeptidase activity (GO:0004177);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	K11142|0|ptr:461132|LAP3; leucine aminopeptidase 3; K11142 cytosol aminopeptidase [EC:3.4.11.1 3.4.11.5] (A)	Arginine and proline metabolism (ko00330);; Glutathione metabolism (ko00480)	[R]	General function prediction only	"Cytosol aminopeptidase family, catalytic domain;; Cytosol aminopeptidase family, N-terminal domain"	Cytosol aminopeptidase GN=LAP3 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: cytosol aminopeptidase [Mustela putorius furo] 
ENSG00000002586(CD99)	--	157.455129	3416	157.2821427	3509	136.3512742	3040	138.8187545	3075	137.6298433	2977	141.475297	3110	0.981953902	-0.182467272	normal	0.965119509	-0.25850617	normal	0.990287215	0.024539745	normal	0.486172081	-0.142609104	normal	--	--	--	K06520|2.21993e-30|ptr:751057|CD99; CD99 antigen; K06520 CD99 antigen (A)	Cell adhesion molecules (CAMs) (ko04514);; Leukocyte transendothelial migration (ko04670)	--	--	CD99 antigen like protein 2	CD99 antigen (Precursor) GN=CD99 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CD99 antigen isoform X4 [Ursus maritimus]
ENSG00000002587(HS3ST1)	--	0.277638614	41	1.03883571	34	2.17921417	65	0.971484333	78	1.41816839	98	0.777096378	112	0.429222302	0.872938507	normal	0.000453233	1.465748842	up	0.364965157	0.763013724	normal	0.010970908	1.021641201	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K01024|0|hsa:9957|HS3ST1, 3OST, 3OST1; heparan sulfate (glucosamine) 3-O-sulfotransferase 1 (EC:2.8.2.23); K01024 [heparan sulfate]-glucosamine 3-sulfotransferase 1 [EC:2.8.2.23] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase domain	Heparan sulfate glucosamine 3-O-sulfotransferase 1 (Precursor) GN=HS3ST1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan sulfate glucosamine 3-O-sulfotransferase 1 [Orcinus orca] 
ENSG00000002726(AOC1)	--	0.02115163	1	0.041594935	2	0.060915069	2	0	0	0.020553221	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: copper ion binding (GO:0005507);; Molecular Function: primary amine oxidase activity (GO:0008131);; Biological Process: amine metabolic process (GO:0009308);; Molecular Function: quinone binding (GO:0048038);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K11182|0|hsa:26|AOC1, ABP, ABP1, DAO, DAO1, KAO; amine oxidase, copper containing 1 (EC:1.4.3.22); K11182 diamine oxidase [EC:1.4.3.22] (A)"	Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tryptophan metabolism (ko00380)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Copper amine oxidase, enzyme domain;; Copper amine oxidase, N2 domain;; Copper amine oxidase, N3 domain"	Amiloride-sensitive amine oxidase [copper-containing] (Precursor) GN=AOC1 OS=Homo sapiens (Human) PE=1 SV=4	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: amiloride-sensitive amine oxidase [copper-containing] isoform X2 [Oryctolagus cuniculus]
ENSG00000002745(WNT16)	--	0	0	0	0	0	0	0	0	0	0	0.021608632	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K01558|0|ggo:101138602|WNT16; protein Wnt-16 isoform 1; K01558 wingless-type MMTV integration site family, member 16 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-16 (Precursor) GN=WNT16 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein Wnt-16 isoform X1 [Galeopterus variegatus]
ENSG00000002746(HECW1)	--	2.185501125	475	2.472966546	524	2.224572771	486	1.730936983	379	2.087628493	470	1.70892404	371	0.826693366	-0.355272214	normal	0.953443655	-0.177790497	normal	0.750144808	-0.396412318	normal	0.170799444	-0.304779779	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	"K12167|0|ptr:463367|HECW1; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1; K12167 E3 ubiquitin-protein ligase HECW1 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain;; C2 domain	E3 ubiquitin-protein ligase HECW1 GN=HECW1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase HECW1 [Tupaia chinensis]
ENSG00000002822(MAD1L1)	--	32.8005979	1355	26.77093294	1158	32.66713813	1350	31.70319642	1316	33.18436875	1411	29.07973589	1245	0.98101089	-0.072881763	normal	0.938085565	0.263344193	normal	0.976642506	-0.124959298	normal	0.954960941	0.019006641	normal	--	--	Biological Process: mitotic spindle assembly checkpoint (GO:0007094);; 	"K06638|0|hsa:8379|MAD1L1, MAD1, PIG9, TP53I9, TXBP181; MAD1 mitotic arrest deficient-like 1 (yeast); K06638 mitotic spindle assembly checkpoint protein MAD1 (A)"	Cell cycle (ko04110);; Progesterone-mediated oocyte maturation (ko04914);; Viral carcinogenesis (ko05203)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mitotic checkpoint protein	Mitotic spindle assembly checkpoint protein MAD1 GN=MAD1L1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: mitotic spindle assembly checkpoint protein MAD1 isoform X1 [Tupaia chinensis]
ENSG00000002834(LASP1)	--	226.8298243	17125	213.4720198	16491	236.047238	18091	253.2572946	19175	210.2627449	15701	222.3165481	16753	0.996717174	0.132279107	normal	0.996866294	-0.092240325	normal	0.996797612	-0.119133782	normal	0.948080514	-0.023717123	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Nebulin repeat;; Variant SH3 domain;; LIM domain;; SH3 domain;; Variant SH3 domain	LIM and SH3 domain protein 1 GN=LASP1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: LIM and SH3 domain protein 1 [Pteropus alecto]
ENSG00000002919(SNX11)	--	13.09785865	451	14.8691548	496	11.75374704	483	14.61730009	550	15.4834163	572	15.68192518	482	0.924411011	0.254685238	normal	0.952739967	0.183726494	normal	0.971434342	-0.011246236	normal	0.584775034	0.144153759	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17924|1.15398e-152|hsa:29916|SNX11; sorting nexin 11; K17924 sorting nexin-10/11 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain	Sorting nexin-11 GN=SNX11 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-11 [Ursus maritimus] 
ENSG00000003056(M6PR)	--	93.28945762	4029	115.220526	5146	97.30868673	4245	115.077314	5091	103.166911	4483	154.544918	6885	0.952059182	0.306590794	normal	0.981530403	-0.220344073	normal	0.008481954	0.689206027	normal	0.480164412	0.273980381	normal	--	--	--	K10089|0|ptr:736013|M6PR; mannose-6-phosphate receptor (cation dependent); K10089 cation-dependent mannose-6-phosphate receptor (A)	Lysosome (ko04142);; Phagosome (ko04145)	--	--	Mannose-6-phosphate receptor	Cation-dependent mannose-6-phosphate receptor (Precursor) GN=M6PR OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: cation-dependent mannose-6-phosphate receptor [Oryctolagus cuniculus] 
ENSG00000003096(KLHL13)	--	2.067583358	115	5.165205795	90	1.3946504	77	1.03016768	57	1.70348867	93	1.171051419	64	0.027785773	-1.02359817	normal	0.970313788	0.025458337	normal	0.960741943	-0.269268821	normal	0.373226704	-0.419172029	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10447|0|nle:100607581|KLHL13; kelch-like 13 (Drosophila); K10447 kelch-like protein 9/13 (A)	Ubiquitin mediated proteolysis (ko04120)	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; BTB/POZ domain;; BTB And C-terminal Kelch;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 13 GN=KLHL13 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 13-like isoform 3 [Ovis aries] 
ENSG00000003137(CYP26B1)	--	2.6441965	160	1.864388211	100	1.973038827	141	4.07062699	255	3.7282617	283	2.609284526	173	0.220207143	0.636710685	normal	1.18E-08	1.465626562	up	0.929543279	0.284030781	normal	0.031381243	0.804391687	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K12664|0|ptr:738157|cytochrome P450 26B1; K12664 cytochrome P450, family 26, subfamily B (A)"	Retinol metabolism (ko00830)	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 26B1 GN=CYP26B1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 26B1-like isoform X1 [Ochotona princeps]
ENSG00000003147(ICA1)	--	2.644286317	95	2.584381754	86	2.95757261	102	1.864043672	76	2.62785451	102	3.20752709	112	0.938325693	-0.346480425	normal	0.957638086	0.221159617	normal	0.96630122	0.124870798	normal	0.991257485	0.015483118	normal	--	--	Molecular Function: protein domain specific binding (GO:0019904);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Arfaptin-like domain;; Islet cell autoantigen ICA69, C-terminal domain"	Islet cell autoantigen 1 GN=ICA1 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: islet cell autoantigen 1 isoform X1 [Lipotes vexillifer]
ENSG00000003249(DBNDD1)	--	32.328804	1346	27.70564499	1169	36.12062305	1544	32.385938	1337	31.05990303	1300	26.41447125	1122	0.982323483	-0.040464863	normal	0.974758102	0.131648584	normal	0.470589252	-0.468351026	normal	0.576681518	-0.1320499	normal	--	--	--	--	--	--	--	Dysbindin (Dystrobrevin binding protein 1)	Dysbindin domain-containing protein 1 GN=DBNDD1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: dysbindin domain-containing protein 1 [Lipotes vexillifer]
ENSG00000003393(ALS2)	--	10.556621	1047	10.70152	1109	9.864779	1048	6.830692	674	6.91888	695	8.248398	829	0.016912007	-0.665046084	normal	0.010074539	-0.694393353	normal	0.841155076	-0.345923558	normal	0.000256083	-0.564321877	normal	[S]	Function unknown	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K04575|0|pps:100982876|ALS2; amyotrophic lateral sclerosis 2 (juvenile); K04575 amyotrophic lateral sclerosis 2 protein (A)	Amyotrophic lateral sclerosis (ALS) (ko05014)	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat;; MORN repeat;; Vacuolar sorting protein 9 (VPS9) domain;; RhoGEF domain	Alsin GN=ALS2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: alsin [Ursus maritimus]
ENSG00000003400(CASP10)	--	2.758822933	212	2.572333702	192	2.813673017	183	2.218196412	190	1.973166871	138	2.330284694	178	0.951371521	-0.187461046	normal	0.705701553	-0.493259686	normal	0.966364347	-0.047856834	normal	0.527901597	-0.235913173	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K04400|0|pps:100972863|CASP10; caspase 10, apoptosis-related cysteine peptidase; K04400 caspase 10 [EC:3.4.22.63] (A)"	Apoptosis (ko04210);; RIG-I-like receptor signaling pathway (ko04622);; TNF signaling pathway (ko04668);; Tuberculosis (ko05152);; Hepatitis B (ko05161)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain;; Death effector domain	Caspase-10 subunit p12 (Precursor) GN=CASP10 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: caspase-10 [Camelus ferus]
ENSG00000003402(CFLAR)	--	27.65185677	1580	26.41769924	1807	32.24854005	1910	31.9190459	2060	23.0129242	1578	27.86100764	1989	0.860754496	0.351587359	normal	0.963953463	-0.216731582	normal	0.985979372	0.050140291	normal	0.818107656	0.065964194	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K04724|0|hsa:8837|CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS; CASP8 and FADD-like apoptosis regulator; K04724 CASP8 and FADD-like apoptosis regulator (A)"	NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; TNF signaling pathway (ko04668);; Chagas disease (American trypanosomiasis) (ko05142)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Death effector domain;; Caspase domain	CASP8 and FADD-like apoptosis regulator subunit p12 (Precursor) GN=CFLAR OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: CASP8 and FADD-like apoptosis regulator isoform X1 [Galeopterus variegatus]
ENSG00000003436(TFPI)	--	56.31391065	2199	90.67759013	3360	67.4118092	2203	27.51386274	1170	28.32475124	1089	46.57902	1882	2.81E-06	-0.940254693	normal	0	-1.645511277	down	0.962125222	-0.235319343	normal	0.035614772	-0.92670882	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; 	K03909|0|ggo:101150295|TFPI; tissue factor pathway inhibitor isoform 1; K03909 tissue factor pathway inhibitor (A)	Complement and coagulation cascades (ko04610)	[O]	"Posttranslational modification, protein turnover, chaperones"	Kunitz/Bovine pancreatic trypsin inhibitor domain	Tissue factor pathway inhibitor (Precursor) GN=TFPI OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tissue factor pathway inhibitor [Tursiops truncatus]
ENSG00000003509(NDUFAF7)	--	11.5817435	414	11.28472162	423	12.621557	452	10.09739669	354	8.58816816	314	8.367261	311	0.9233681	-0.255686185	normal	0.634407207	-0.449447163	normal	0.29128333	-0.545486279	normal	0.057075182	-0.418351823	normal	[S]	Function unknown	--	"K18164|0|pps:100980761|NDUFAF7; NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; K18164 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 7 (A)"	--	[S]	Function unknown	Putative S-adenosyl-L-methionine-dependent methyltransferase	"NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 (Precursor) GN=NDUFAF7 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: NADH dehydrogenase [ubiquinone] complex I, assembly factor 7 isoformX1 [Equus caballus]"
ENSG00000003756(RBM5)	--	15.10691001	1095	15.94890634	1132	13.71893832	985	16.29063805	1097	15.77663745	1154	13.52145018	1045	0.980322018	-0.028160132	normal	0.980631298	0.006334327	normal	0.977514106	0.076901229	normal	0.963294031	0.015730735	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13094|0|hsa:10181|RBM5, G15, LUCA15, RMB5; RNA binding motif protein 5; K13094 RNA-binding protein 5/10 (A)"	--	[R]	General function prediction only	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; G-patch domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Zn-finger in Ran binding protein and others;; DExH-box splicing factor binding site"	RNA-binding protein 5 GN=RBM5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: RNA-binding protein 5 isoform X1 [Equus caballus] 
ENSG00000003987(MTMR7)	--	0.3725059	24	0.362577	24	0.623356	37	0.765276	47	0.524898	35	0.2792479	18	0.769101048	0.897093285	normal	0.965967686	0.496842025	normal	0.801160454	-0.988743222	normal	0.826877892	0.21147867	normal	--	--	--	K18083|0|hsa:9108|MTMR7; myotubularin related protein 7 (EC:3.1.3.-); K18083 myotubularin-related protein 6/7/8 [EC:3.1.3.-] (A)	--	[R]	General function prediction only	Myotubularin-like phosphatase domain	Myotubularin-related protein 7 GN=MTMR7 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: myotubularin-related protein 7 isoform X1 [Galeopterus variegatus]
ENSG00000003989(SLC7A2)	--	3.074252121	298	1.555005837	172	1.77056292	206	5.842495246	579	9.263310653	958	9.934923808	1072	9.77E-05	0.923942622	normal	0	2.445947133	up	0	2.362814639	up	9.84E-05	1.928911096	up	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13864|0|hsa:6542|SLC7A2, ATRC2, CAT2, HCAT2; solute carrier family 7 (cationic amino acid transporter, y+ system), member 2; K13864 solute carrier family 7 (cationic amino acid transporter), member 2 (A)"	--	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease;; C-terminus of AA_permease	Cationic amino acid transporter 2 GN=SLC7A2 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: cationic amino acid transporter 2 isoform X1 [Felis catus]
ENSG00000004059(ARF5)	--	81.43271663	1488	74.72141625	1396	76.54200671	1454	90.06788626	1678	90.91362448	1653	92.85580843	1732	0.977304225	0.142397415	normal	0.960067407	0.222139865	normal	0.95291506	0.243887526	normal	0.27107118	0.201888498	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07940|2.23317e-131|tup:102477248|ARF5; ADP-ribosylation factor 5; K07940 ADP-ribosylation factor 5 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Ras family;; Gtr1/RagA G protein conserved region;; Miro-like protein;; 50S ribosome-binding GTPase	ADP-ribosylation factor 5 GN=ARF5 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor 5 isoform X1 [Myotis lucifugus]
ENSG00000004139(SARM1)	--	3.8111451	516	3.1470874	589	2.630369	473	1.650435002	283	2.179145058	301	2.362020005	480	0.000276279	-0.893750185	normal	2.12E-05	-0.986318897	normal	0.971295123	0.012861959	normal	0.060913533	-0.588499842	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[W]	Extracellular structures	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; TIR domain	Sterile alpha and TIR motif-containing protein 1 (Precursor) GN=SARM1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: sterile alpha and TIR motif-containing protein 1 [Galeopterus variegatus]
ENSG00000004142(POLDIP2)	--	85.2174	3218	85.772679	3281	87.640692	3346	97.12698	3678	100.49125	3764	93.51255	3542	0.985019569	0.161852571	normal	0.983498169	0.176628422	normal	0.990158067	0.073802901	normal	0.509389078	0.13671188	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: DNA binding (GO:0003677);; 	"K17809|0|pps:100981280|POLDIP2; polymerase (DNA-directed), delta interacting protein 2; K17809 polymerase delta-interacting protein 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Protein of unknown function (DUF525);; Hemimethylated DNA-binding protein YccV like	Polymerase delta-interacting protein 2 GN=POLDIP2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: polymerase delta-interacting protein 2 isoform X1 [Elephantulus edwardii]
ENSG00000004399(PLXND1)	--	11.04107006	1474	8.093942869	1181	11.2468287	1368	15.42033811	2144	19.20075831	2705	18.55083301	2635	0.303560125	0.50929367	normal	5.58E-10	1.17317289	up	2.93E-06	0.936684023	normal	3.48E-07	0.875117342	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06822|0|hsa:23129|PLXND1, PLEXD1; plexin D1; K06822 plexin D (A)"	--	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; IPT/TIG domain;; Sema domain;; Plexin repeat	Plexin-D1 (Precursor) GN=PLXND1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: plexin-D1, partial [Galeopterus variegatus]"
ENSG00000004455(AK2)	--	68.42287723	2017	67.26093531	1987	75.66182322	2057	76.00181006	2459	64.93828031	2073	57.2064384	1799	0.956837411	0.254852343	normal	0.986263605	0.039672125	normal	0.970449834	-0.201479529	normal	0.883493494	0.040775682	normal	[F]	Nucleotide transport and metabolism	Molecular Function: adenylate kinase activity (GO:0004017);; 	K00939|2.6944e-175|ptr:456723|AK2; adenylate kinase 2; K00939 adenylate kinase [EC:2.7.4.3] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	"Adenylate kinase;; Adenylate kinase, active site lid"	"Adenylate kinase 2, mitochondrial, N-terminally processed {ECO:0000255|HAMAP-Rule:MF_03168} OS=Homo sapiens (Human) PE=1 SV=2"	F	Nucleotide transport and metabolism	"PREDICTED: adenylate kinase 2, mitochondrial isoform X1 [Oryctolagus cuniculus]"
ENSG00000004468(CD38)	--	5.727354788	495	5.160054927	457	5.496640851	481	2.414425196	216	3.234119	288	3.229121989	284	4.08E-08	-1.221318044	down	0.039452161	-0.684671075	normal	0.006596584	-0.765269334	normal	4.25E-06	-0.883057444	normal	--	--	Molecular Function: NAD+ nucleosidase activity (GO:0003953);; 	"K01242|0|hsa:952|CD38, ADPRC_1, T10; CD38 molecule (EC:3.2.2.6 2.4.99.20); K01242 ADP-ribosyl cyclase 1 [EC:3.2.2.6 2.4.99.20] (A)"	Nicotinate and nicotinamide metabolism (ko00760);; Calcium signaling pathway (ko04020);; Hematopoietic cell lineage (ko04640);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Pancreatic secretion (ko04972);; Epstein-Barr virus infection (ko05169)	--	--	ADP-ribosyl cyclase	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 GN=CD38 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 [Galeopterus variegatus]
ENSG00000004478(FKBP4)	--	72.46622373	3891	58.29973557	3152	82.40099973	4398	86.69903765	4579	78.17925248	4230	49.96284068	2647	0.982393852	0.203985011	normal	0.819015078	0.402796209	normal	0.001617353	-0.740449049	normal	0.979237197	-0.020308506	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K09571|0|hsa:2288|FKBP4, FKBP51, FKBP52, FKBP59, HBI, Hsp56, PPIase, p52; FK506 binding protein 4, 59kDa (EC:5.2.1.8); K09571 FK506-binding protein 4/5 [EC:5.2.1.8] (A)"	Estrogen signaling pathway (ko04915)	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	"Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed GN=FKBP4 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP4 [Odobenus rosmarus divergens]
ENSG00000004487(KDM1A)	--	34.85269025	2085	28.92729552	1845	32.88342657	2063	43.44411401	2754	47.18178379	2839	30.59448862	1890	0.845267502	0.370410767	normal	0.072016813	0.5999362	normal	0.981174	-0.134545947	normal	0.313164772	0.298311298	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K11450|0|ptr:456614|KDM1A, AOF2, KDM1; lysine (K)-specific demethylase 1A; K11450 lysine-specific histone demethylase 1 [EC:1.-.-.-] (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Flavin containing amine oxidoreductase;; SWIRM domain;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain	Lysine-specific histone demethylase 1A GN=KDM1A OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: lysine-specific histone demethylase 1A isoform X4 [Canis lupus familiaris]
ENSG00000004534(RBM6)	--	9.22038238	763	8.758045015	725	9.674291165	775	10.40898162	850	10.11346561	825	8.784741468	737	0.969952267	0.124709527	normal	0.962407676	0.164664413	normal	0.973601265	-0.080661708	normal	0.79658904	0.07048287	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; G-patch domain"	RNA-binding protein 6 GN=RBM6 OS=Homo sapiens (Human) PE=1 SV=5	R	General function prediction only	PREDICTED: RNA-binding protein 6 isoform X1 [Equus przewalskii] 
ENSG00000004660(CAMKK1)	--	9.1009677	699	5.469833	427	5.23521566	407	5.0561336	381	5.7523022	443	3.885234851	295	8.20E-05	-0.903599382	normal	0.969221138	0.031534423	normal	0.569819084	-0.470542531	normal	0.369916765	-0.476331282	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K07359|0|ggo:101123728|CAMKK1; calcium/calmodulin-dependent protein kinase kinase 1 isoform 1; K07359 calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17] (A)	AMPK signaling pathway (ko04152);; Adipocytokine signaling pathway (ko04920);; Oxytocin signaling pathway (ko04921);; Alcoholism (ko05034)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Calcium/calmodulin-dependent protein kinase kinase 1 GN=CAMKK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase kinase 1 isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000004700(RECQL)	--	29.60951916	1772	32.41239849	1867	34.26297912	2031	33.2872763	2025	29.95416124	1753	31.63508268	1829	0.977372327	0.16157992	normal	0.981723799	-0.112228652	normal	0.977978219	-0.159301549	normal	0.892446898	-0.037481317	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K10899|0|hsa:5965|RECQL, RECQL1, RecQ1; RecQ helicase-like (EC:3.6.4.12); K10899 ATP-dependent DNA helicase Q1 [EC:3.6.4.12] (A)"	--	[R]	General function prediction only	"Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; RQC domain;; Type III restriction enzyme, res subunit"	ATP-dependent DNA helicase Q1 GN=RECQL OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: ATP-dependent DNA helicase Q1 [Orycteropus afer afer]
ENSG00000004766(VPS50)	--	6.365190029	394	6.860287115	448	7.041726309	454	6.192200592	427	6.302789015	381	7.507322873	505	0.966557942	0.084890153	normal	0.923800801	-0.25420262	normal	0.960662168	0.144841995	normal	1	-0.001825075	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function N-terminal domain (DUF2450);; Protein of unknown function C-terminus (DUF2451)	Coiled-coil domain-containing protein 132 GN=CCDC132 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 132 [Equus przewalskii]
ENSG00000004776(HSPB6)	--	0.427584211	8	0.475299394	11	0.531809684	12	0.168584286	4	0.401175525	9	1.053510936	23	--	--	--	--	--	--	0.957220836	0.851661507	normal	--	--	--	--	--	Molecular Function: structural constituent of eye lens (GO:0005212);; 	"K09545|4.87627e-74|ptr:745747|HSPB6; heat shock protein, alpha-crystallin-related, B6; K09545 heat shock protein beta-6 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Hsp20/alpha crystallin family;; Alpha crystallin A chain, N terminal"	Heat shock protein beta-6 GN=HSPB6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein beta-6 [Eptesicus fuscus]
ENSG00000004777(ARHGAP33)	--	3.4683799	280	2.788971148	238	3.23153389	265	2.3230873	184	2.072475878	156	2.367021785	200	0.189147562	-0.632239472	normal	0.273037645	-0.625891345	normal	0.788242883	-0.411571042	normal	0.03300713	-0.5569905	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K17933|0|pon:100440795|ARHGAP33; Rho GTPase activating protein 33; K17933 Rho GTPase-activating protein 33 (A)	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; PX domain	Rho GTPase-activating protein 33 GN=ARHGAP33 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 33 isoform X1 [Leptonychotes weddellii]
ENSG00000004779(NDUFAB1)	--	92.3721186	694	96.99044858	746	89.43999229	698	116.5766379	917	95.92620161	722	98.13676683	754	0.790313243	0.370438412	normal	0.973419739	-0.068462267	normal	0.971187266	0.102831638	normal	0.544478765	0.140608047	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	--	"K03955|6.23178e-109|ptr:744435|NDUFAB1; NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa; K03955 NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[CIQ]	"Energy production and conversion;; Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Phosphopantetheine attachment site	"Acyl carrier protein, mitochondrial (Precursor) GN=NDUFAB1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: acyl carrier protein, mitochondrial [Oryctolagus cuniculus]"
ENSG00000004799(PDK4)	--	91.7656	5269	56.1732	3219	67.4693	3804	14.1855	821	35.7634	2048	29.155	1674	0	-2.710597223	down	0.012805337	-0.673423178	normal	6.77E-11	-1.191774464	down	0.001057794	-1.455291339	down	[T]	Signal transduction mechanisms	--	"K00898|0|hsa:5166|PDK4; pyruvate dehydrogenase kinase, isozyme 4 (EC:2.7.11.2); K00898 pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] (A)"	--	[T]	Signal transduction mechanisms	"Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial (Precursor) GN=PDK4 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: pyruvate dehydrogenase kinase, isozyme 4 [Oryctolagus cuniculus]"
ENSG00000004809(SLC22A16)	--	0	0	0.062000945	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08212|0|hsa:85413|SLC22A16, CT2, FLIPT2, OAT6, OCT6, OKB1, dJ261K5.1; solute carrier family 22 (organic cation/carnitine transporter), member 16; K08212 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 16 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 16 GN=SLC22A16 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 22 member 16 [Galeopterus variegatus]
ENSG00000004838(ZMYND10)	--	0.319261203	15	0.35551452	10	0.143083008	8	0.459030742	15	0.21681673	12	0.249878637	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MYND finger	Zinc finger MYND domain-containing protein 10 GN=ZMYND10 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger MYND domain-containing protein 10 [Ovis aries]
ENSG00000004846(ABCB5)	--	0	0	0.04587218	1	0	0	0	0	0.0470509	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05660|0|hsa:340273|ABCB5, ABCB5alpha, ABCB5beta, EST422562; ATP-binding cassette, sub-family B (MDR/TAP), member 5; K05660 ATP-binding cassette, subfamily B (MDR/TAP), member 5 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"ABC transporter transmembrane region;; ABC transporter;; RecF/RecN/SMC N terminal domain;; AAA domain;; Predicted ATPase of the ABC class;; AAA domain;; AAA ATPase domain;; P-loop containing region of AAA domain;; AAA domain;; AAA domain;; Protein of unknown function, DUF258;; AAA domain (dynein-related subfamily)"	ATP-binding cassette sub-family B member 5 GN=ABCB5 OS=Homo sapiens (Human) PE=1 SV=4	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family B member 5 [Equus przewalskii]
ENSG00000004848(ARX)	--	1.814920439	84	1.056480532	50	1.520410467	74	1.066500643	50	1.220212176	57	2.72304414	129	0.571401295	-0.76104165	normal	0.973613077	0.162987854	normal	0.233285667	0.781241928	normal	0.896960747	0.164162417	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09452|1.95462e-143|ggo:101147736|ARX; homeobox protein ARX; K09452 homeobox protein aristaless-related (A)	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Homeobox protein ARX GN=ARX OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox protein ARX [Orcinus orca]
ENSG00000004864(SLC25A13)	--	28.61506	1469	35.02061	1806	32.11679	1633	23.72637	1229	24.34693	1245	29.55006	1518	0.922010095	-0.287852055	normal	0.154141207	-0.557512947	normal	0.98028031	-0.113535362	normal	0.075630768	-0.318640834	normal	--	--	--	"K15105|0|hsa:10165|SLC25A13, ARALAR2, CITRIN, CTLN2; solute carrier family 25 (aspartate/glutamate carrier), member 13; K15105 solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein;; EF-hand domain;; EF-hand domain pair;; EF hand;; EF-hand domain pair	Calcium-binding mitochondrial carrier protein Aralar2 GN=SLC25A13 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: calcium-binding mitochondrial carrier protein Aralar2 isoform X1 [Tupaia chinensis]
ENSG00000004866(ST7)-2	--	8.770032753	359	9.844169953	427	9.364167072	408	12.47219454	483	11.67381247	475	14.89070364	527	0.752437062	0.395742362	normal	0.961319565	0.131822092	normal	0.817338233	0.359766002	normal	0.193939593	0.293748532	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000004897(CDC27)	--	45.76170945	3464	41.71652953	3195	46.38849356	3294	47.53032971	3455	49.73395904	3487	41.23019874	2954	0.991026058	-0.03457013	normal	0.988479788	0.10469643	normal	0.983522327	-0.165381949	normal	0.915484468	-0.029894154	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03350|0|hsa:996|CDC27, ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, H-NUC, HNUC, NUC2; cell division cycle 27; K03350 anaphase-promoting complex subunit 3 (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Tetratricopeptide repeat;; TPR repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; ChAPs (Chs5p-Arf1p-binding proteins);; Tetratricopeptide repeat"	Cell division cycle protein 27 homolog GN=CDC27 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cell division cycle protein 27 homolog isoform X1 [Camelus ferus]
ENSG00000004961(HCCS)	--	24.34325263	777	22.47473732	781	22.0468187	709	25.353152	879	28.2622462	920	24.99800704	803	0.967070138	0.146843193	normal	0.950505635	0.214501724	normal	0.96120231	0.170980031	normal	0.403709977	0.177262698	normal	--	--	Molecular Function: holocytochrome-c synthase activity (GO:0004408);; Cellular Component: mitochondrion (GO:0005739);; 	K01764|1.62648e-173|ptr:465489|cytochrome c-type heme lyase; K01764 cytochrome c heme-lyase [EC:4.4.1.17] (A)	Porphyrin and chlorophyll metabolism (ko00860)	[CO]	"Energy production and conversion;; Posttranslational modification, protein turnover, chaperones"	Cytochrome c/c1 heme lyase	Cytochrome c-type heme lyase GN=HCCS OS=Homo sapiens (Human) PE=1 SV=1	CO	"Energy production and conversion;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: cytochrome c-type heme lyase [Ailuropoda melanoleuca] 
ENSG00000004975(DVL2)	--	24.21428159	1245	21.95102732	1264	22.41011059	1276	18.53517031	997	19.3719742	934	21.6559027	1191	0.837897522	-0.350827606	normal	0.533223158	-0.457289444	normal	0.977676024	-0.107614313	normal	0.078438659	-0.298486992	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K02353|0|ptr:455236|DVL2; dishevelled segment polarity protein 2; K02353 segment polarity protein dishevelled (A)	Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[R]	General function prediction only	"Segment polarity protein dishevelled (Dsh) C terminal;; DIX domain;; Dishevelled specific domain;; PDZ domain (Also known as DHR or GLGF);; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	Segment polarity protein dishevelled homolog DVL-2 GN=DVL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: segment polarity protein dishevelled homolog DVL-2 isoform X2 [Bos mutus] 
ENSG00000005001(PRSS22)	--	0.336203375	7	0.09248646	2	0.136031707	2	0.616586	14	0.68515647	13	1.609030932	34	--	--	--	--	--	--	5.09E-05	3.331506258	up	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09626|0|hsa:64063|PRSS22, BSSP-4, hBSSP-4; protease, serine, 22; K09626 protease, serine, 22 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Brain-specific serine protease 4 (Precursor) GN=PRSS22 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: brain-specific serine protease 4 [Equus caballus] 
ENSG00000005007(UPF1)	--	19.90373	2143	18.28724	2010	20.11061	2223	21.84738	2357	25.02982	2693	20.75648	2245	0.984888297	0.106414882	normal	0.784480575	0.400331124	normal	0.987864944	0.005912052	normal	0.362357454	0.173147776	normal	[L]	"Replication, recombination and repair"	"Biological Process: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity (GO:0016787);; "	"K14326|0|hsa:5976|UPF1, HUPF1, NORF1, RENT1, pNORF1, smg-2; UPF1 regulator of nonsense transcripts homolog (yeast); K14326 regulator of nonsense transcripts 1 [EC:3.6.4.-] (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"RNA helicase (UPF2 interacting domain);; AAA domain;; AAA domain;; Part of AAA domain;; AAA domain;; Type III restriction enzyme, res subunit;; Uncharacterized conserved protein (DUF2075)"	Regulator of nonsense transcripts 1 GN=UPF1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: regulator of nonsense transcripts 1 isoform X1 [Mustela putorius furo] 
ENSG00000005020(SKAP2)	--	21.10921611	1393	19.43531363	1281	20.7028151	1342	19.77462794	1315	19.29151633	1268	20.70821719	1366	0.978272059	-0.113835465	normal	0.981451441	-0.036099453	normal	0.982903251	0.017262089	normal	0.867909997	-0.045341257	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PH domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Src kinase-associated phosphoprotein 2 GN=SKAP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: src kinase-associated phosphoprotein 2 [Orycteropus afer afer]
ENSG00000005022(SLC25A5)	--	484.812	8528	437.1	7795	461.115	8187	468.517	8296	456.71	8015	438.3	7736	0.995224875	-0.070610908	normal	0.99524948	0.018723357	normal	0.994625524	-0.090021433	normal	0.865024612	-0.048887262	normal	--	--	--	"K05863|0|hsa:292|SLC25A5, 2F1, AAC2, ANT2, T2, T3; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Parkinson's disease (ko05012);; Huntington's disease (ko05016);; HTLV-I infection (ko05166)	[C]	Energy production and conversion	Mitochondrial carrier protein	"ADP/ATP translocase 2, N-terminally processed GN=SLC25A5 OS=Homo sapiens (Human) PE=1 SV=7"	C	Energy production and conversion	PREDICTED: ADP/ATP translocase 2 [Oryctolagus cuniculus] 
ENSG00000005059(MCUB)	--	12.042902	406	10.101913	342	10.749	359	15.800906	538	15.79217	532	15.60174	528	0.790619047	0.374061059	normal	0.107610008	0.613810763	normal	0.257375192	0.546353518	normal	0.009175313	0.508332974	normal	--	--	--	--	--	[R]	General function prediction only	"Protein of unknown function, DUF607"	"Calcium uniporter regulatory subunit MCUb, mitochondrial (Precursor) GN=CCDC109B OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	PREDICTED: mitochondrial calcium uniporter regulatory subunit MCUb [Galeopterus variegatus]
ENSG00000005073(HOXA11)	--	0.3813031	16	0.264784	11	0.120876023	4	0.708366733	30	0.65827723	26	0.44596773	18	0.937090093	0.817932334	normal	0.871413256	1.117187971	normal	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K09296|0|hsa:3207|HOXA11, HOX1, HOX1I; homeobox A11; K09296 homeobox protein HoxA/C/D11 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Protein of unknown function (DUF3528);; Homeobox domain	Homeobox protein Hox-A11 GN=HOXA11 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein Hox-A11 [Tursiops truncatus]
ENSG00000005075(POLR2J)	--	49.1757	658	47.58545	645	48.26379	657	56.33085	773	57.63366	766	52.77734	717	0.952093443	0.201114961	normal	0.94271052	0.226131667	normal	0.968857824	0.117529272	normal	0.41106954	0.18153443	normal	[K]	Transcription	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: protein dimerization activity (GO:0046983);; "	K03008|2.30213e-96|ggo:101130894|DNA-directed RNA polymerase II subunit RPB11-a-like; K03008 DNA-directed RNA polymerase II subunit RPB11 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpb3/Rpb11 dimerisation domain;; RNA polymerase Rpb3/Rpb11 dimerisation domain	DNA-directed RNA polymerase II subunit RPB11-b2 GN=POLR2J3 OS=Homo sapiens (Human) PE=3 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase II subunit RPB11-a isoform X1 [Eptesicus fuscus]
ENSG00000005100(DHX33)	--	293.68872	6944	281.9677198	6791	296.493983	7067	299.8163071	7315	282.6219266	6793	269.181112	6488	0.994865666	0.044249114	normal	0.994622308	-0.020997061	normal	0.992575799	-0.131586133	normal	0.902702768	-0.035862499	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	K17820|0|pps:100974169|DHX33; DEAH (Asp-Glu-Ala-His) box polypeptide 33; K17820 ATP-dependent RNA helicase DHX33 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase	Putative ATP-dependent RNA helicase DHX33 GN=DHX33 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: putative ATP-dependent RNA helicase DHX33 isoform X1 [Condylura cristata]
ENSG00000005108(THSD7A)	--	3.526348355	713	4.034452693	820	3.422777146	684	5.178042255	1050	6.573638997	1323	6.887816524	1394	0.239667752	0.526642737	normal	0.01703706	0.667712562	normal	4.27E-07	1.017262591	up	0.000163298	0.744269388	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thrombospondin type 1 domain	Thrombospondin type-1 domain-containing protein 7A (Precursor) GN=THSD7A OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thrombospondin type-1 domain-containing protein 7A [Ceratotherium simum simum]
ENSG00000005156(LIG3)	--	13.22203203	1061	11.84477338	980	11.73624698	995	8.546468277	745	10.07077739	883	10.431934	909	0.193655417	-0.540005953	normal	0.963959123	-0.171515878	normal	0.970547376	-0.138487372	normal	0.120712638	-0.279635755	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA ligase (ATP) activity (GO:0003910);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: zinc ion binding (GO:0008270);; 	"K10776|0|pps:100977351|LIG3; ligase III, DNA, ATP-dependent; K10776 DNA ligase 3 [EC:6.5.1.1] (A)"	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	ATP dependent DNA ligase domain;; DNA ligase N terminus;; Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region;; ATP dependent DNA ligase C terminal region	DNA ligase 3 GN=LIG3 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA ligase 3 isoform 1 [Ceratotherium simum simum] 
ENSG00000005175(RPAP3)	--	19.60672298	1175	17.567249	1175	22.25599046	1324	18.658219	1228	19.30945276	1137	17.0510644	1021	0.981269919	0.032775618	normal	0.979084567	-0.068765083	normal	0.773010901	-0.382712444	normal	0.5129292	-0.139291456	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	TPR repeat;; Tetratricopeptide repeat;; Potential Monad-binding region of RPAP3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RNA polymerase II-associated protein 3 GN=RPAP3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: RNA polymerase II-associated protein 3 [Galeopterus variegatus] 
ENSG00000005187(ACSM3)	--	7.22445798	296	5.410667757	192	4.842579	187	3.568951374	154	5.84842	211	4.47435	167	0.00053473	-0.96641395	normal	0.960639519	0.113854484	normal	0.955722848	-0.170025749	normal	0.42829059	-0.364636454	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01896|0|hsa:6296|ACSM3, SA, SAH; acyl-CoA synthetase medium-chain family member 3 (EC:6.2.1.2); K01896 medium-chain acyl-CoA synthetase [EC:6.2.1.2] (A)"	Butanoate metabolism (ko00650)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	"Acyl-coenzyme A synthetase ACSM3, mitochondrial (Precursor) GN=ACSM3 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: acyl-coenzyme A synthetase ACSM3, mitochondrial [Mustela putorius furo] "
ENSG00000005189(AC004381.6)	--	3.567737639	142	3.5847283	124	2.73651115	112	4.568217001	159	2.88236069	115	2.907108	124	0.962157816	0.130964018	normal	0.963275488	-0.128504921	normal	0.964190453	0.136793874	normal	0.93492335	0.052023562	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; 	K14570|0|ggo:101150930|putative RNA exonuclease NEF-sp-like isoform 1; K14570 RNA exonuclease 1 [EC:3.1.-.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[L]	"Replication, recombination and repair"	"Exonuclease;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Putative RNA exonuclease NEF-sp GN=44M2.3 OS=Homo sapiens (Human) PE=2 SV=1	L	"Replication, recombination and repair"	PREDICTED: putative RNA exonuclease NEF-sp-like isoform 1 [Ceratotherium simum simum]
ENSG00000005194(CIAPIN1)	--	27.50744782	950	23.93231	900	27.71490903	1015	35.1566205	1171	35.80493155	1248	30.35541059	1017	0.927475556	0.270514765	normal	0.564743085	0.449550406	normal	0.979789152	-0.005443388	normal	0.187641475	0.24084602	normal	[S]	Function unknown	Cellular Component: cytoplasm (GO:0005737);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: iron-sulfur cluster assembly (GO:0016226);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	--	--	[S]	Function unknown	"Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis;; Methyltransferase domain"	Anamorsin {ECO:0000255|HAMAP-Rule:MF_03115} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: anamorsin [Bos mutus] 
ENSG00000005206(SPPL2B)	--	13.0106017	868	12.84599911	738	9.562720738	723	13.69597783	776	11.98230236	853	15.29759775	985	0.957082944	-0.192110752	normal	0.957626633	0.187141428	normal	0.594817343	0.437050429	normal	0.537197072	0.14593169	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Cellular Component: integral component of membrane (GO:0016021);; 	K09597|0|pps:100979944|SPPL2B; signal peptide peptidase like 2B; K09597 signal peptide peptidase-like 2B [EC:3.4.23.-] (A)	--	[R]	General function prediction only	Signal peptide peptidase;; PA domain	Signal peptide peptidase-like 2B (Precursor) GN=SPPL2B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: signal peptide peptidase-like 2B [Ceratotherium simum simum]
ENSG00000005238(FAM214B)	--	6.817790832	394	5.445740014	328	6.504292239	378	7.98017172	467	9.404656997	548	6.954388126	412	0.942071545	0.213628792	normal	0.016228463	0.716471566	normal	0.963264602	0.115523842	normal	0.107741218	0.354178203	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF4210);; Chromosome segregation during meiosis	Protein FAM214B GN=FAM214B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM214B isoform X1 [Tupaia chinensis] 
ENSG00000005243(COPZ2)	--	7.150713308	96	7.16388578	105	5.87419251	82	11.80856473	163	11.9942945	160	9.007858574	122	0.225017893	0.723948215	normal	0.590390237	0.579449905	normal	0.745786996	0.556428572	normal	0.067051634	0.630661713	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	Coatomer subunit zeta-2 GN=COPZ2 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit zeta-2 [Loxodonta africana]
ENSG00000005249(PRKAR2B)	--	7.345912461	400	5.482471553	301	6.7445971	365	4.49406688	248	5.203457656	282	3.785446281	205	0.02541448	-0.716958683	normal	0.960637976	-0.114898336	normal	0.003443151	-0.835877916	normal	0.012999219	-0.557867935	normal	--	--	--	"K04739|0|hsa:5577|PRKAR2B, PRKAR2, RII-BETA; protein kinase, cAMP-dependent, regulatory, type II, beta (EC:2.7.11.1); K04739 cAMP-dependent protein kinase regulator (A)"	Apoptosis (ko04210);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	Cyclic nucleotide-binding domain;; Regulatory subunit of type II PKA R-subunit	cAMP-dependent protein kinase type II-beta regulatory subunit GN=PRKAR2B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: cAMP-dependent protein kinase type II-beta regulatory subunit [Mustela putorius furo] 
ENSG00000005302(MSL3)	--	9.475802915	451	10.3920278	475	10.27671504	471	13.74004933	635	11.25322834	527	14.01616772	657	0.530798614	0.461466389	normal	0.962952904	0.128061693	normal	0.493220435	0.47058986	normal	0.070953619	0.359662067	normal	--	--	--	"K18403|0|pon:100173442|MSL3, MSL3L1; male-specific lethal 3 homolog (Drosophila); K18403 male-specific lethal 3 (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	MRG;; RNA binding activity-knot of a chromodomain	Male-specific lethal 3 homolog GN=MSL3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: male-specific lethal 3 homolog isoformX2 [Canis lupus familiaris]
ENSG00000005339(CREBBP)	--	9.613405042	1898	11.44582548	2139	10.36926606	1862	8.957610817	1799	11.32871307	2314	12.81744435	2481	0.98261164	-0.108027229	normal	0.985304215	0.091963303	normal	0.750841265	0.405490974	normal	0.621837397	0.140317896	normal	[BK]	Chromatin structure and dynamics;; Transcription	"Cellular Component: histone acetyltransferase complex (GO:0000123);; Molecular Function: transcription cofactor activity (GO:0003712);; Molecular Function: transcription coactivator activity (GO:0003713);; Molecular Function: histone acetyltransferase activity (GO:0004402);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: histone acetylation (GO:0016573);; "	"K04498|0|hsa:1387|CREBBP, CBP, KAT3A, RSTS; CREB binding protein (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48] (A)"	cAMP signaling pathway (ko04024);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; TGF-beta signaling pathway (ko04350);; Adherens junction (ko04520);; Jak-STAT signaling pathway (ko04630);; Long-term potentiation (ko04720);; Melanogenesis (ko04916);; Thyroid hormone signaling pathway (ko04919);; Huntington's disease (ko05016);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Prostate cancer (ko05215)	[K]	Transcription	"Histone acetylation protein;; Creb binding;; KIX domain;; TAZ zinc finger;; Domain of Unknown Function (DUF902);; Bromodomain;; Zinc finger, ZZ type"	CREB-binding protein GN=CREBBP OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: CREB-binding protein [Oryctolagus cuniculus]
ENSG00000005421(PON1)	--	0.241412	10	0.192765	8	0.0961632	3	0.214878	9	0.280741	11	0.11941	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: arylesterase activity (GO:0004064);; Biological Process: biosynthetic process (GO:0009058);; Molecular Function: strictosidine synthase activity (GO:0016844);; 	"K01045|0|hsa:5444|PON1, ESA, MVCD5, PON; paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81); K01045 arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1] (A)"	--	--	--	Arylesterase;; SMP-30/Gluconolaconase/LRE-like region;; Strictosidine synthase	Serum paraoxonase/arylesterase 1 GN=PON1 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: serum paraoxonase/arylesterase 1 [Tupaia chinensis]
ENSG00000005436(GCFC2)	--	9.265960571	512	8.078545538	422	8.528367	448	7.648445347	371	6.673104416	389	5.10870081	274	0.439949084	-0.493807621	normal	0.959370731	-0.138382699	normal	0.021389325	-0.714498627	normal	0.037390512	-0.440502902	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09061|0|pps:100979312|GCFC2; GC-rich sequence DNA-binding factor 2; K09061 GC-rich sequence DNA-binding factor (A)	--	[K]	Transcription	GC-rich sequence DNA-binding factor-like protein	GC-rich sequence DNA-binding factor 2 GN=GCFC2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: GC-rich sequence DNA-binding factor 2 isoform X1 [Equus caballus]
ENSG00000005448(WDR54)	--	66.287613	1139	57.81512813	937	62.566881	1078	44.60151214	781	38.219089	647	40.30070227	703	0.10609143	-0.574263907	normal	0.177794417	-0.554626035	normal	0.041576814	-0.623959625	normal	0.000144153	-0.587130354	normal	--	--	--	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 54 GN=WDR54 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 54 isoform X2 [Sus scrofa]
ENSG00000005469(CROT)	--	8.103419817	363	8.961297793	391	9.974971331	427	11.91359475	521	12.54649287	543	9.288383509	411	0.460697126	0.488746605	normal	0.598839819	0.450871257	normal	0.968386027	-0.063161093	normal	0.183575738	0.299128017	normal	--	--	"Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K05940|0|hsa:54677|CROT, COT; carnitine O-octanoyltransferase (EC:2.3.1.137); K05940 carnitine O-octanoyltransferase [EC:2.3.1.137] (A)"	Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Choline/Carnitine o-acyltransferase	Peroxisomal carnitine O-octanoyltransferase GN=CROT OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: peroxisomal carnitine O-octanoyltransferase isoform X1 [Galeopterus variegatus]
ENSG00000005471(ABCB4)	--	0.041147124	3	0.071866337	6	0.090051631	6	0	0	0.013347017	0	0.027322421	2	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05659|0|hsa:5244|ABCB4, ABC21, GBD1, ICP3, MDR2, MDR2/3, MDR3, PFIC-3, PGY3; ATP-binding cassette, sub-family B (MDR/TAP), member 4 (EC:3.6.3.44); K05659 ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:3.6.3.44] (A)"	ABC transporters (ko02010);; Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"ABC transporter transmembrane region;; ABC transporter;; RecF/RecN/SMC N terminal domain;; AAA domain;; Predicted ATPase of the ABC class;; AAA ATPase domain;; Protein of unknown function, DUF258;; ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA domain;; Zeta toxin;; AAA domain;; P-loop containing region of AAA domain;; Rad17 cell cycle checkpoint protein;; AAA domain (dynein-related subfamily)"	Multidrug resistance protein 3 GN=ABCB4 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: multidrug resistance protein 3 isoform X2 [Tupaia chinensis]
ENSG00000005483(KMT2E)	--	15.48554631	1564	15.34266252	1804	16.92910795	1688	14.65169058	1523	15.08940296	1544	15.65163478	1655	0.982851774	-0.069088052	normal	0.953710559	-0.245730216	normal	0.984786844	-0.036741885	normal	0.575638874	-0.119566636	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K09189|0|hsa:55904|KMT2E, HDCMC04P, MLL5, NKp44L; lysine (K)-specific methyltransferase 2E (EC:2.1.1.43); K09189 histone-lysine N-methyltransferase MLL5 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[R]	General function prediction only	PHD-finger;; SET domain	Histone-lysine N-methyltransferase 2E GN=KMT2E OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone-lysine N-methyltransferase 2E isoform X1 [Galeopterus variegatus] 
ENSG00000005486(RHBDD2)	--	49.50797134	1460	44.01693288	1301	43.85906891	1309	38.24328454	1130	47.24525041	1397	42.64173049	1269	0.729114333	-0.399997868	normal	0.980273799	0.081193412	normal	0.981524278	-0.053002276	normal	0.575238441	-0.121389807	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	K09652|0|pps:100991900|RHBDD2; rhomboid domain containing 2; K09652 rhomboid domain-containing protein 2 (A)	--	[S]	Function unknown	Rhomboid family	Rhomboid domain-containing protein 2 GN=RHBDD2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: rhomboid domain-containing protein 2 [Galeopterus variegatus]
ENSG00000005513(SOX8)	--	0.447976	24	0.2006	11	0.211866	11	0.334044	18	0.323015	17	0.0366274	2	0.982856122	-0.415081694	normal	--	--	--	--	--	--	--	--	--	--	--	--	K09270|0|hsa:30812|SOX8; SRY (sex determining region Y)-box 8; K09270 transcription factor SOX7/8/10/18 (SOX group E/F) (A)	--	[K]	Transcription	HMG (high mobility group) box;; Sox developmental protein N terminal;; HMG-box domain	Transcription factor SOX-8 GN=SOX8 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor SOX-8 [Orcinus orca]
ENSG00000005700(IBTK)	--	29.47562819	2889	32.74340341	3190	32.637026	3138	26.630625	2660	23.76533541	2352	32.57960851	3182	0.983752753	-0.14989311	normal	0.588404776	-0.460839414	normal	0.990573493	0.011791398	normal	0.341093593	-0.190396917	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; BTB/POZ domain;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Regulator of chromosome condensation (RCC1) repeat	Inhibitor of Bruton tyrosine kinase GN=IBTK OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: inhibitor of Bruton tyrosine kinase [Ceratotherium simum simum]
ENSG00000005801(ZNF195)	--	13.74986055	560	11.80731602	483	9.883830571	450	15.27146967	537	13.93235036	579	13.72784624	578	0.968849794	-0.091081777	normal	0.932803828	0.239428139	normal	0.827891095	0.351807263	normal	0.525184117	0.161051307	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:450964|ZNF195; zinc finger protein 195; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc ribbon domain"	Zinc finger protein 195 GN=ZNF195 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 184-like [Orcinus orca]
ENSG00000005810(MYCBP2)	--	7.116382066	1667	6.701098234	1804	7.269640465	1845	7.745584269	1740	6.896708739	1670	7.634612161	1784	0.98506367	0.030972997	normal	0.979387104	-0.13266217	normal	0.985072949	-0.056749336	normal	0.831092618	-0.05453409	normal	--	--	--	"K10693|0|hsa:23077|MYCBP2, PAM; MYC binding protein 2, E3 ubiquitin protein ligase; K10693 E3 ubiquitin-protein ligase MYCBP2 [EC:6.3.2.19] (A)"	--	[T]	Signal transduction mechanisms	PHR domain;; Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat;; Bacterial SH3 domain;; Ring finger domain;; Filamin/ABP280 repeat	E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase MYCBP2 isoformX2 [Canis lupus familiaris]
ENSG00000005812(FBXL3)	--	9.065642	452	12.11818766	569	8.338688	401	8.64574	454	9.5009	493	9.84307	508	0.970518185	-0.02438005	normal	0.938058003	-0.227616987	normal	0.85848081	0.331820552	normal	0.982012688	0.011800438	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10269|0|pps:100983358|FBXL3; F-box and leucine-rich repeat protein 3; K10269 F-box and leucine-rich repeat protein 3 (A)	Circadian rhythm (ko04710)	--	--	F-box-like;; F-box domain	F-box/LRR-repeat protein 3 GN=FBXL3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 3 isoform X2 [Mustela putorius furo] 
ENSG00000005844(ITGAL)	--	0.11238143	11	0.157962743	14	0.156121365	11	0.038088509	2	0.103584627	8	0.187258854	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05718|0|ptr:454045|ITGAL; integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide); K05718 integrin alpha L (A)"	Rap1 signaling pathway (ko04015);; Cell adhesion molecules (CAMs) (ko04514);; Natural killer cell mediated cytotoxicity (ko04650);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Malaria (ko05144);; Staphylococcus aureus infection (ko05150);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Rheumatoid arthritis (ko05323);; Viral myocarditis (ko05416)	[W]	Extracellular structures	"Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella;; von Willebrand factor type A domain;; FG-GAP repeat;; Integrin alpha cytoplasmic region"	Integrin alpha-L (Precursor) GN=ITGAL OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: integrin alpha-L isoform X1 [Equus caballus]
ENSG00000005882(PDK2)	--	5.3016554	258	4.652203011	232	4.807259286	199	4.098490001	172	7.162352351	295	4.8023	245	0.269524585	-0.611302882	normal	0.88453931	0.323290884	normal	0.914663497	0.289734168	normal	0.971712671	0.026974838	normal	[T]	Signal transduction mechanisms	--	"K00898|0|pps:100992308|PDK2; pyruvate dehydrogenase kinase, isozyme 2; K00898 pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] (A)"	--	[T]	Signal transduction mechanisms	"Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial (Precursor) GN=PDK2 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial [Vicugna pacos] "
ENSG00000005884(ITGA3)	--	262.9084135	27179	211.8160919	22379	256.6977717	27291	207.4679526	21594	174.5735717	18071	176.018987	18408	0.971250109	-0.36267107	normal	0.979602717	-0.329870926	normal	0.305962972	-0.576344667	normal	0.020932599	-0.425681278	normal	--	--	--	"K06482|0|ptr:455111|ITGA3; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); K06482 integrin alpha 3 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Hematopoietic cell lineage (ko04640);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella;; FG-GAP repeat"	Integrin alpha-3 light chain (Precursor) GN=ITGA3 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: integrin alpha-3 isoform X1 [Galeopterus variegatus]
ENSG00000005889(ZFX)	--	7.373554696	777	10.42600023	911	9.08305275	894	10.49112919	959	11.14665607	1010	10.85006833	1042	0.921273363	0.272298584	normal	0.971680116	0.127205168	normal	0.953921682	0.212384022	normal	0.31280558	0.200897799	normal	[R]	General function prediction only	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: metal ion binding (GO:0046872);; "	--	--	[R]	General function prediction only	"Zfx / Zfy transcription activation region;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc-finger domain"	Zinc finger X-chromosomal protein GN=ZFX OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger X-chromosomal protein-like isoform 1 [Dasypus novemcinctus]
ENSG00000005893(LAMP2)	--	88.61819997	3804	99.42346946	4175	86.787796	3459	84.991107	3751	83.26366135	3619	103.1509905	4285	0.991368603	-0.051053481	normal	0.977052356	-0.227523039	normal	0.950167239	0.300530484	normal	0.986272296	0.006029043	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K06528|0|hsa:3920|LAMP2, CD107b, LAMP-2, LAMPB, LGP110; lysosomal-associated membrane protein 2; K06528 lysosomal-associated membrane protein 1/2 (A)"	Lysosome (ko04142);; Phagosome (ko04145);; Tuberculosis (ko05152)	[R]	General function prediction only	Lysosome-associated membrane glycoprotein (Lamp)	Lysosome-associated membrane glycoprotein 2 (Precursor) GN=LAMP2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: lysosome-associated membrane glycoprotein 2 isoform X1 [Galeopterus variegatus]
ENSG00000005961(ITGA2B)	--	0.924816845	61	1.058259126	72	0.918653366	62	0.37344664	23	0.462779048	30	0.298106179	20	0.031129441	-1.379258188	normal	0.037361128	-1.242762979	normal	0.005826984	-1.569776058	down	0.001862935	-1.439052599	down	--	--	--	"K06476|0|hsa:3674|ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3, PPP1R93; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); K06476 integrin alpha 2B (A)"	Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Hematopoietic cell lineage (ko04640);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella;; Integrin alpha cytoplasmic region"	"Integrin alpha-IIb light chain, form 2 (Precursor) GN=ITGA2B OS=Homo sapiens (Human) PE=1 SV=3"	W	Extracellular structures	PREDICTED: integrin alpha-IIb [Balaenoptera acutorostrata scammoni]
ENSG00000005981(ASB4)	--	1.7166399	46	0.838206019	29	1.737667462	44	1.234998853	62	2.981775608	118	1.518622007	65	0.954104508	0.388588914	normal	7.53E-08	1.948936685	up	0.908720848	0.539305355	normal	0.10473994	1.021463178	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10326|0|pon:100435882|ASB4; ankyrin repeat and SOCS box containing 4; K10326 ankyrin repeat and SOCS box protein 4 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SOCS box	Ankyrin repeat and SOCS box protein 4 GN=ASB4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 4 [Galeopterus variegatus]
ENSG00000006007(GDE1)	--	41.7628797	2229	41.08592901	2182	41.01928149	2158	50.4067624	2694	50.87712169	2703	46.38238305	2482	0.96389749	0.242368833	normal	0.943944677	0.287304655	normal	0.975300836	0.193390345	normal	0.162534894	0.240895015	normal	[C]	Energy production and conversion	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; 	--	--	[C]	Energy production and conversion	Glycerophosphoryl diester phosphodiesterase family	Glycerophosphodiester phosphodiesterase 1 GN=GDE1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: glycerophosphodiester phosphodiesterase 1 [Galeopterus variegatus]
ENSG00000006015(C19orf60)	--	33.82297819	376	31.39566123	371	31.99316251	367	32.13243126	368	34.601467	372	32.23467	369	0.967423545	-0.061604692	normal	0.968159085	-0.017472	normal	0.969147578	-0.000448844	normal	0.9508736	-0.027689958	normal	--	--	--	--	--	--	--	DNA repair REX1-B	Uncharacterized protein C19orf60 GN=C19orf60 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C19orf60 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000006016(CRLF1)	--	0.167885921	5	0.630989366	20	0.201515039	5	1.047520684	32	2.832577235	78	0.48621789	14	0.010807291	2.332647459	normal	4.39E-05	1.865547255	up	--	--	--	0.252917395	2.023796533	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Fibronectin type III domain;; Erythropoietin receptor, ligand binding;; Interleukin-6 receptor alpha chain, binding"	Cytokine receptor-like factor 1 (Precursor) GN=CRLF1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: cytokine receptor-like factor 1 [Galeopterus variegatus]
ENSG00000006025(OSBPL7)	--	3.348417054	269	3.322198058	263	3.316723663	272	4.206084258	313	3.757998406	295	3.762849349	301	0.949335535	0.186734798	normal	0.956713592	0.14344648	normal	0.958820547	0.1371403	normal	0.635174568	0.155804261	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Oxysterol-binding protein;; Pleckstrin homology domain;; PH domain	Oxysterol-binding protein-related protein 7 GN=OSBPL7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 7 [Equus caballus]
ENSG00000006042(TMEM98)	--	26.867633	645	32.770935	803	27.6133519	681	19.83478583	449	21.0186238	510	18.15999499	471	0.204094975	-0.551830906	normal	0.021233174	-0.674720303	normal	0.239011958	-0.53877216	normal	0.0005246	-0.595307311	normal	--	--	--	--	--	--	--	Grap2 and cyclin-D-interacting	Transmembrane protein 98 GN=TMEM98 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 98 [Equus caballus] 
ENSG00000006047(YBX2)	--	1.223042	33	0.792897	26	0.60244321	20	0.181297027	6	0.272063	8	0.118486	4	0.011240958	-2.223165208	normal	0.536232183	-1.551346981	normal	0.475613848	-1.97130074	normal	0.000867173	-2.156399886	down	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09277|3.1997e-132|hsa:51087|YBX2, CONTRIN, CSDA3, DBPC, MSY2; Y box binding protein 2; K09277 Y-box-binding protein 2 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	'Cold-shock' DNA-binding domain	Y-box-binding protein 2 GN=YBX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	"PREDICTED: Y-box-binding protein 2, partial [Trichechus manatus latirostris]"
ENSG00000006062(MAP3K14)	--	16.550614	1459	21.916602	1909	26.725584	2592	17.43368461	1634	17.47234798	1633	13.852105	1296	0.978138166	0.132463981	normal	0.954810686	-0.246507479	normal	2.17E-07	-1.007443196	down	0.354422467	-0.406367813	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04466|0|hsa:9020|MAP3K14, FTDCR1B, HS, HSNIK, NIK; mitogen-activated protein kinase kinase kinase 14 (EC:2.7.11.25); K04466 mitogen-activated protein kinase kinase kinase 14 [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; T cell receptor signaling pathway (ko04660);; TNF signaling pathway (ko04668);; Intestinal immune network for IgA production (ko04672);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase 14 GN=MAP3K14 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 14 [Galeopterus variegatus]
ENSG00000006071(ABCC8)	--	1.151432755	92	1.38720904	88	1.145344881	108	0.427276586	33	1.114139922	54	0.39258213	36	0.000603361	-1.467301456	down	0.631186796	-0.710232298	normal	4.88E-05	-1.553724647	down	0.001495004	-1.247790514	down	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05032|0|hsa:6833|ABCC8, ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, SUR1delta2, TNDM2; ATP-binding cassette, sub-family C (CFTR/MRP), member 8; K05032 ATP-binding cassette subfamily C (CFTR/MRP) member 8 (A)"	ABC transporters (ko02010);; Insulin secretion (ko04911);; Type II diabetes mellitus (ko04930)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter transmembrane region;; ABC transporter;; AAA domain;; AAA domain	ATP-binding cassette sub-family C member 8 GN=ABCC8 OS=Homo sapiens (Human) PE=1 SV=6	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family C member 8 isoform X2 [Sus scrofa]
ENSG00000006118(TMEM132A)	--	63.776566	3844	45.59929656	2947	59.05657865	3739	106.30934	6554	91.9072848	5667	81.36221338	5101	0.00195413	0.73870648	normal	6.68E-06	0.921564735	normal	0.713251031	0.439683344	normal	7.63E-05	0.696361345	normal	--	--	--	"K17599|0|hsa:54972|TMEM132A, GBP, HSPA5BP1; transmembrane protein 132A; K17599 transmembrane protein 132 (A)"	--	[S]	Function unknown	--	Transmembrane protein 132A (Precursor) GN=TMEM132A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 132A [Camelus bactrianus]
ENSG00000006125(AP2B1)	--	118.489492	11992	114.810625	11331	123.532196	12134	170.804361	16926	156.2130612	15752	138.329531	13730	0.779941038	0.466286016	normal	0.82491377	0.453781692	normal	0.994388773	0.169965042	normal	0.040156521	0.366583996	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K11825|0|umr:103667291|AP2B1; adaptor-related protein complex 2, beta 1 subunit; K11825 AP-2 complex subunit beta-1 (A)"	Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Adaptin N terminal region;; Beta2-adaptin appendage, C-terminal sub-domain;; non-SMC mitotic condensation complex subunit 1;; HEAT repeats;; HEAT repeat;; Adaptin C-terminal domain;; Armadillo/beta-catenin-like repeat;; Nuclear condensing complex subunits, C-term domain;; HEAT-like repeat"	AP-2 complex subunit beta GN=AP2B1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	AP-2 complex subunit beta [Bos taurus] 
ENSG00000006194(ZNF263)	--	15.3405194	719	18.307581	768	12.325306	648	16.54904	749	16.063475	874	19.8911889	833	0.975613666	0.028082889	normal	0.963279076	0.164796063	normal	0.823764546	0.353302196	normal	0.401274226	0.18099927	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:10127|ZNF263, FPM315, ZKSCAN12, ZSCAN44; zinc finger protein 263; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 263 GN=ZNF263 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 263 [Ceratotherium simum simum]
ENSG00000006210(CX3CL1)	--	0.049203173	3	0	0	0	0	0.132149274	8	0.289203149	18	0.077071914	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K05508|0|hsa:6376|CX3CL1, ABCD-3, C3Xkine, CXC3, CXC3C, NTN, NTT, SCYD1, fractalkine, neurotactin; chemokine (C-X3-C motif) ligand 1; K05508 C-X3-C motif chemokine 1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; TNF signaling pathway (ko04668)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	Processed fractalkine (Precursor) GN=CX3CL1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: fractalkine [Tupaia chinensis]
ENSG00000006282(SPATA20)	--	55.419695	2922	44.83228995	2449	45.601952	2490	39.64394368	2085	46.2993346	2424	44.11036312	2370	0.288210492	-0.517417259	normal	0.987989886	-0.03620716	normal	0.987054173	-0.079500628	normal	0.230873838	-0.21337183	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[R]	General function prediction only	"Protein of unknown function, DUF255;; Thioredoxin-like;; N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase)"	Spermatogenesis-associated protein 20 (Precursor) GN=SPATA20 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: spermatogenesis-associated protein 20 isoform X4 [Canis lupus familiaris]
ENSG00000006283(CACNA1G)	--	18.31165851	2744	9.654654854	1409	14.126263	2063	3.316599687	433	5.064419207	715	2.477078528	384	0	-2.690308007	down	1.19E-06	-0.998548341	normal	0	-2.429224395	down	0.000165535	-2.041625669	down	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04854|0|mcf:101925139|uncharacterized LOC101925139; K04854 voltage-dependent calcium channel T type alpha-1G (A)	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; Circadian entrainment (ko04713);; Type II diabetes mellitus (ko04930)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Polycystin cation channel	Voltage-dependent T-type calcium channel subunit alpha-1G GN=CACNA1G OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent T-type calcium channel subunit alpha-1G [Galeopterus variegatus]
ENSG00000006327(TNFRSF12A)	--	147.6589177	2075	164.2514808	2400	164.4609208	2434	283.5186719	4143	270.0186824	3787	211.9960293	3000	7.92E-07	0.966216402	normal	0.034008774	0.636272701	normal	0.942710604	0.293177533	normal	0.001286879	0.639753645	normal	--	--	--	"K05149|1.85418e-33|pon:100431323|TNFRSF12A; tumor necrosis factor receptor superfamily, member 12A; K05149 tumor necrosis factor receptor superfamily member 12A (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain	Tumor necrosis factor receptor superfamily member 12A (Precursor) GN=TNFRSF12A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 12A [Loxodonta africana]
ENSG00000006377(DLX6)	--	0.024585	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09314|8.82644e-150|mcf:102145891|DLX6; distal-less homeobox 6; K09314 homeobox protein DLX1/4/6 (A)	--	[K]	Transcription	Homeobox domain	Homeobox protein DLX-6 GN=DLX6 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein DLL-1 [Orcinus orca]
ENSG00000006432(MAP3K9)	--	3.854973459	835	4.636069197	1017	4.443803652	965	4.471250178	957	4.713552526	1011	5.534439	1195	0.964813442	0.165625645	normal	0.978923234	-0.029918619	normal	0.904890444	0.299695518	normal	0.518031013	0.146641977	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04417|0|mcf:102123979|MAP3K9; mitogen-activated protein kinase kinase kinase 9; K04417 mitogen-activated protein kinase kinase kinase 9 [EC:2.7.11.25] (A)	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Mitogen-activated protein kinase kinase kinase 9 GN=MAP3K9 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 9 isoform 1 [Trichechus manatus latirostris]
ENSG00000006451(RALA)	--	18.790026	625	16.71011	609	15.978913	558	29.1756	1171	30.982402	1202	30.082942	1095	6.45E-05	0.873388132	normal	6.71E-06	0.957772072	normal	4.70E-06	0.962405739	normal	1.89E-10	0.931006375	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07834|8.55342e-136|ptr:737424|RALA; v-ral simian leukemia viral oncogene homolog A (ras related); K07834 Ras-related protein Ral-A (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Pathways in cancer (ko05200);; Pancreatic cancer (ko05212)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein Ral-A (Precursor) GN=RALA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Ral-A isoform X1 [Tupaia chinensis]
ENSG00000006453(BAIAP2L1)	--	31.8714	2319	30.11838	2183	31.2255	2266	26.891	1959	28.1789	2047	25.57717	1871	0.946297488	-0.274019866	normal	0.983396264	-0.114145907	normal	0.939096837	-0.284420512	normal	0.201218012	-0.224913412	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: plasma membrane organization (GO:0007009);; 	--	--	--	--	IRSp53/MIM homology domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 GN=BAIAP2L1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: BAI1-associated protein 2-like 1 isoformX1 [Canis lupus familiaris]
ENSG00000006459(KDM7A)	--	0.857819816	132	0.821136162	123	0.866520775	126	1.202661736	186	1.456589326	224	1.651580967	252	0.778824196	0.459408756	normal	0.022416814	0.835693315	normal	0.000945329	0.983201849	normal	0.00475676	0.776774256	normal	--	--	--	"K11445|0|hsa:80853|KDM7A, JHDM1D; lysine (K)-specific demethylase 7A; K11445 JmjC domain-containing histone demethylation protein 1D/E/F (A)"	--	[B]	Chromatin structure and dynamics	"JmjC domain, hydroxylase;; PHD-finger;; Cupin-like domain"	Lysine-specific demethylase 7A GN=KDM7A OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: lysine-specific demethylase 7 [Dasypus novemcinctus]
ENSG00000006468(ETV1)	--	5.528801597	355	6.081754602	275	6.628792689	376	5.213727769	390	5.365915809	327	5.802106937	306	0.963982325	0.104391698	normal	0.936232496	0.227285091	normal	0.892673704	-0.30413399	normal	1	0.002583394	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09431|0|pps:100987148|ETV1; ets variant 1; K09431 ets translocation variant 1 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	PEA3 subfamily ETS-domain transcription factor N terminal domain;; Ets-domain	ETS translocation variant 1 GN=ETV1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS translocation variant 1-like isoform X1 [Tupaia chinensis]
ENSG00000006530(AGK)	--	10.94326281	740	9.0911	593	10.44504345	676	13.629895	883	13.035934	821	10.018085	679	0.946167462	0.223630431	normal	0.57900101	0.446950992	normal	0.97511636	-0.001898876	normal	0.283938688	0.224428425	normal	[IR]	Lipid transport and metabolism;; General function prediction only	Molecular Function: kinase activity (GO:0016301);; 	"K09881|0|hsa:55750|AGK, CATC5, CTRCT38, MTDPS10, MULK; acylglycerol kinase (EC:2.7.1.107 2.7.1.94); K09881 acylglycerol kinase [EC:2.7.1.94] (A)"	Glycerolipid metabolism (ko00561)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase catalytic domain	"Acylglycerol kinase, mitochondrial (Precursor) GN=AGK OS=Homo sapiens (Human) PE=1 SV=2"	IT	Lipid transport and metabolism;; Signal transduction mechanisms	"PREDICTED: acylglycerol kinase, mitochondrial isoform X3 [Canis lupus familiaris] "
ENSG00000006534(ALDH3B1)	--	120.2705169	5923	116.185447	5733	107.2440539	5340	107.886619	5348	124.7905039	5987	135.6735467	6752	0.988465436	-0.178112232	normal	0.993792953	0.041105823	normal	0.946901357	0.330100402	normal	0.789087237	0.069132391	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00129|0|hsa:221|ALDH3B1, ALDH4, ALDH7; aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5); K00129 aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Histidine metabolism (ko00340);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; beta-Alanine metabolism (ko00410);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[C]	Energy production and conversion	Aldehyde dehydrogenase family;; Acyl-CoA reductase (LuxC)	Aldehyde dehydrogenase family 3 member B1 (Precursor) GN=ALDH3B1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: aldehyde dehydrogenase family 3 member B1 [Galeopterus variegatus]
ENSG00000006576(PHTF2)	--	13.58934929	881	13.72281027	958	12.38019504	857	10.62087135	741	9.416010532	686	11.8292972	834	0.914084055	-0.279967535	normal	0.353585983	-0.50230189	normal	0.976779066	-0.047454373	normal	0.140761944	-0.274876532	normal	--	--	--	--	--	--	--	Male germ-cell putative homeodomain transcription factor	Putative homeodomain transcription factor 2 GN=PHTF2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: putative homeodomain transcription factor 2 isoform 1 [Ceratotherium simum simum]
ENSG00000006606(CCL26)	--	2.919570809	13	1.750831522	8	3.415041174	15	4.019585	20	7.653610953	34	4.350820859	20	--	--	--	0.058048629	1.881187562	normal	0.986502376	0.374000628	normal	--	--	--	--	--	--	"K05514|2.31164e-49|hsa:10344|CCL26, IMAC, MIP-4a, MIP-4alpha, SCYA26, TSC-1; chemokine (C-C motif) ligand 26; K05514 C-C motif chemokine, other (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	C-C motif chemokine 26 (Precursor) GN=CCL26 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	chemokine ligand 26-like protein precursor [Sus scrofa] 
ENSG00000006607(FARP2)	--	9.011617826	946	8.061940722	914	8.164779252	932	5.982244728	639	6.834689418	674	4.369762275	517	0.07755338	-0.595671039	normal	0.524390087	-0.459982113	normal	0.00015556	-0.856563468	normal	6.48E-05	-0.631161677	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K06082|0|ptr:460083|FARP2; FERM, RhoGEF and pleckstrin domain protein 2; K06082 FERM, RhoGEF and pleckstrin domain protein 2 (A)"	Rap1 signaling pathway (ko04015);; Adherens junction (ko04520)	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; FERM C-terminal PH-like domain;; FERM N-terminal domain;; FERM adjacent (FA);; FERM central domain	"FERM, RhoGEF and pleckstrin domain-containing protein 2 GN=FARP2 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: FERM, RhoGEF and pleckstrin domain-containing protein 2 isoform X1 [Equus caballus]"
ENSG00000006611(USH1C)	--	0.253233145	5	0.139453014	7	0.117743012	1	0.104576924	5	0.459192571	20	0.319769673	16	--	--	--	0.884358178	1.318772788	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain	Harmonin GN=USH1C OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: harmonin [Panthera tigris altaica]
ENSG00000006625(GGCT)	--	42.51608838	706	51.047085	854	46.39977617	767	58.05500647	991	54.41767	901	53.57897733	904	0.513872414	0.457540671	normal	0.976300191	0.055768329	normal	0.945000184	0.228389531	normal	0.203193823	0.243328451	normal	--	--	--	K00682|2.16121e-138|pps:100984104|GGCT; gamma-glutamylcyclotransferase; K00682 gamma-glutamylcyclotransferase [EC:2.3.2.4] (A)	Glutathione metabolism (ko00480)	[S]	Function unknown	AIG2-like family;; AIG2-like family	Gamma-glutamylcyclotransferase GN=GGCT OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: gamma-glutamylcyclotransferase isoform X2 [Galeopterus variegatus]
ENSG00000006634(DBF4)	--	7.374159	559	7.831329809	591	7.210369	538	7.498927667	572	7.449928346	566	7.287388592	555	0.973009029	0.002328274	normal	0.969472111	-0.08356411	normal	0.972172711	0.036489168	normal	0.967825638	-0.017136955	normal	[LD]	"Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	"K06629|0|hsa:10926|DBF4, ASK, CHIF, DBF4A, ZDBF1; DBF4 zinc finger; K06629 activator of S phase kinase (A)"	Cell cycle (ko04110)	[LD]	"Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	DBF zinc finger;; BRCA1 C Terminus (BRCT) domain	Protein DBF4 homolog A GN=DBF4 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: protein DBF4 homolog A [Ceratotherium simum simum]
ENSG00000006638(TBXA2R)	--	0.849316157	24	0.762669004	25	0.6128341	21	0.671929099	17	0.633882002	17	0.390548107	10	0.980414922	-0.49081959	normal	0.975388751	-0.538118359	normal	0.949922874	-0.975006497	normal	0.368965262	-0.69265355	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04264|0|pps:100988035|TBXA2R; thromboxane A2 receptor; K04264 thromboxane A2 receptor (A)	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Platelet activation (ko04611)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Putative binding domain	Thromboxane A2 receptor GN=TBXA2R OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: thromboxane A2 receptor [Odobenus rosmarus divergens]
ENSG00000006652(IFRD1)	--	31.40160999	1032	29.70425054	943	30.44577271	994	26.7737525	920	33.26417841	1071	42.81200162	1456	0.958930464	-0.196259773	normal	0.967100424	0.161958407	normal	0.1814916	0.541716175	normal	0.623059952	0.195584312	normal	--	--	--	--	--	[Z]	Cytoskeleton	Interferon-related developmental regulator (IFRD);; Interferon-related protein conserved region	Interferon-related developmental regulator 1 GN=IFRD1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: interferon-related developmental regulator 1 isoform X1 [Vicugna pacos] 
ENSG00000006695(COX10)	--	13.124274	447	12.743669	446	11.7248	409	11.858693	442	16.00444	575	13.63594	523	0.969622577	-0.046898613	normal	0.842125674	0.344061807	normal	0.839907527	0.345286947	normal	0.357941178	0.221433901	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765);; "	"K02257|0|ptr:465445|COX10; protoheme IX farnesyltransferase, mitochondrial; K02257 protoheme IX farnesyltransferase [EC:2.5.1.-] (A)"	Oxidative phosphorylation (ko00190);; Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	UbiA prenyltransferase family	"Protoheme IX farnesyltransferase, mitochondrial (Precursor) GN=COX10 OS=Homo sapiens (Human) PE=1 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: protoheme IX farnesyltransferase, mitochondrial-like [Pteropus alecto] "
ENSG00000006704(GTF2IRD1)	--	9.803849181	758	11.09463001	789	10.9569719	853	8.46249858	641	9.186099883	701	9.1150135	703	0.917129477	-0.272105109	normal	0.955353211	-0.191647429	normal	0.908168261	-0.286751574	normal	0.200998164	-0.251649359	normal	--	--	--	"K03121|0|hsa:9569|GTF2IRD1, BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1; GTF2I repeat domain containing 1; K03121 transcription initiation factor TFII-I (A)"	Basal transcription factors (ko03022);; cGMP-PKG signaling pathway (ko04022);; Herpes simplex infection (ko05168)	--	--	GTF2I-like repeat	General transcription factor II-I repeat domain-containing protein 1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor II-I repeat domain-containing protein 1 isoform X1 [Myotis brandtii]
ENSG00000006712(PAF1)	--	32.32514	1573	30.282726	1498	33.21650112	1648	30.6618422	1500	34.401834	1661	32.56382	1582	0.981052725	-0.099289104	normal	0.978638122	0.127465651	normal	0.983461916	-0.067195145	normal	0.967635723	-0.013531626	normal	--	--	Biological Process: transcription elongation from RNA polymerase II promoter (GO:0006368);; Biological Process: histone modification (GO:0016570);; Cellular Component: Cdc73/Paf1 complex (GO:0016593);; 	"K15174|0|nle:100594485|PAF1; Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae); K15174 RNA polymerase II-associated factor 1 (A)"	--	[K]	Transcription	Paf1	RNA polymerase II-associated factor 1 homolog GN=PAF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: RNA polymerase II-associated factor 1 homolog [Oryctolagus cuniculus]
ENSG00000006715(VPS41)	--	23.04980818	1446	24.8575534	1673	20.87520613	1627	20.21613589	1454	21.33389401	1432	30.64804213	1915	0.983528062	-0.022848337	normal	0.951868168	-0.245592272	normal	0.961833106	0.226644322	normal	0.993627414	-0.00371405	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Region in Clathrin and VPS	Vacuolar protein sorting-associated protein 41 homolog GN=VPS41 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 41 homolog [Ceratotherium simum simum]
ENSG00000006740(ARHGAP44)	--	4.564187829	315	2.639721312	218	2.621062165	211	1.44982931	110	2.267934132	153	1.589653317	122	2.85E-10	-1.535401222	down	0.584824694	-0.527828019	normal	0.047458616	-0.791102862	normal	0.004686425	-0.971517974	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	BAR domain;; RhoGAP domain	Rho GTPase-activating protein 44 GN=ARHGAP44 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 44 [Ceratotherium simum simum]
ENSG00000006744(ELAC2)	--	36.17749068	2416	34.22273709	2209	37.30167182	2519	44.34210287	2909	43.2059462	2807	31.66672089	2124	0.967379288	0.236933112	normal	0.916997944	0.324011901	normal	0.95814615	-0.254192393	normal	0.673078859	0.112247688	normal	[R]	General function prediction only	Biological Process: tRNA processing (GO:0008033);; 	K00784|0|ptr:450109|ELAC2; elaC ribonuclease Z 2 (EC:3.1.26.11); K00784 ribonuclease Z [EC:3.1.26.11] (A)	RNA transport (ko03013)	[R]	General function prediction only	Beta-lactamase superfamily domain;; tRNase Z endonuclease;; Metallo-beta-lactamase superfamily	Zinc phosphodiesterase ELAC protein 2 (Precursor) GN=ELAC2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc phosphodiesterase ELAC protein 2 [Galeopterus variegatus]
ENSG00000006747(SCIN)	--	0.205728535	6	0.24170002	13	0.073478791	9	0.262144713	21	0.589613991	32	0.78064953	65	0.770965894	1.553664032	normal	0.722695303	1.187588695	normal	2.23E-07	2.653943462	up	0.074461772	2.057125433	normal	--	--	--	K05768|0|hsa:85477|SCIN; scinderin; K05768 gelsolin (A)	Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Viral carcinogenesis (ko05203)	[Z]	Cytoskeleton	Gelsolin repeat	Adseverin GN=SCIN OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: adseverin [Tupaia chinensis]
ENSG00000006756(ARSD)	--	7.826744	749	7.5649354	774	6.367537	638	6.780474006	673	7.035732	704	7.7446887	729	0.956758659	-0.184791319	normal	0.963049264	-0.157861133	normal	0.956640731	0.183663404	normal	0.842595709	-0.058446429	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K12374|0|hsa:414|ARSD, ASD; arylsulfatase D (EC:3.1.6.1); K12374 arylsulfatase D/F/H [EC:3.1.6.-] (A)"	--	[R]	General function prediction only	Sulfatase;; C-terminal region of aryl-sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	Arylsulfatase D (Precursor) GN=ARSD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: arylsulfatase D-like [Galeopterus variegatus]
ENSG00000006757(PNPLA4)	--	9.384654146	212	6.040072849	166	7.731686129	158	8.394186815	232	8.969191134	264	11.23563906	257	0.963042729	0.098545449	normal	0.199732656	0.643242875	normal	0.115367961	0.688337405	normal	0.090522037	0.469318806	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K11157|1.80067e-176|hsa:8228|PNPLA4, DXS1283E, GS2, iPLA2eta; patatin-like phospholipase domain containing 4 (EC:3.1.1.3); K11157 patatin-like phospholipase domain-containing protein 4 [EC:3.1.1.-] (A)"	Retinol metabolism (ko00830)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Patatin-like phospholipase	Patatin-like phospholipase domain-containing protein 4 GN=PNPLA4 OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: patatin-like phospholipase domain-containing protein 4 isoform X1 [Galeopterus variegatus] 
ENSG00000006831(ADIPOR2)	--	44.9239	3065	40.79173	2819	42.14196	2860	36.48981	2504	38.25905	2582	42.9939	2917	0.920687574	-0.322305657	normal	0.98337076	-0.148038019	normal	0.989862675	0.020168237	normal	0.457515211	-0.14852069	normal	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; 	K07297|0|ptr:451742|ADIPOR2; adiponectin receptor 2; K07297 adiponectin receptor (A)	AMPK signaling pathway (ko04152);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Adiponectin receptor protein 2 GN=ADIPOR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: adiponectin receptor protein 2 [Ursus maritimus] 
ENSG00000006837(CDKL3)	--	1.212840726	32	0.679480383	20	1.412885529	26	1.911184948	30	1.54147135	41	0.877162757	28	0.98409514	-0.118084595	normal	0.768966203	0.962426663	normal	0.985544642	0.093388525	normal	0.695101039	0.322862504	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08824|0|hsa:51265|CDKL3, NKIAMRE; cyclin-dependent kinase-like 3 (EC:2.7.11.22); K08824 cyclin-dependent kinase-like [EC:2.7.11.22] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Cyclin-dependent kinase-like 3 GN=CDKL3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-dependent kinase-like 3 [Odobenus rosmarus divergens]
ENSG00000007001(UPP2)	--	0.0264719	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: nucleoside metabolic process (GO:0009116);; 	"K00757|0|hsa:151531|UPP2, UDRPASE2, UP2, UPASE2; uridine phosphorylase 2 (EC:2.4.2.3); K00757 uridine phosphorylase [EC:2.4.2.3] (A)"	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Phosphorylase superfamily	Uridine phosphorylase 2 GN=UPP2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	"Uridine phosphorylase 2, partial [Pteropus alecto]"
ENSG00000007038(PRSS21)	--	0	0	0	0	0	0	0	0	0.139526344	1	0.05542804	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09625|0|pps:100988600|PRSS21; protease, serine, 21 (testisin); K09625 protease, serine, 21 (testisin) [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin	Testisin (Precursor) GN=PRSS21 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: testisin [Galeopterus variegatus]
ENSG00000007047(MARK4)	--	49.7465351	1025	47.1754492	939	45.09864305	991	47.89023764	986	50.92475	1046	37.6436347	819	0.976668214	-0.086664155	normal	0.971274204	0.134054604	normal	0.914734205	-0.282837508	normal	0.779113098	-0.073301845	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08798|0|hsa:57787|MARK4, MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D; MAP/microtubule affinity-regulating kinase 4 (EC:2.7.11.1); K08798 MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase associated domain 1;; Kinase-like;; UBA/TS-N domain;; RIO1 family	MAP/microtubule affinity-regulating kinase 4 GN=MARK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: MAP/microtubule affinity-regulating kinase 4 isoform 1 [Orcinus orca]
ENSG00000007062(PROM1)	--	0	0	0.045887549	3	0	0	0.328905417	5	0.043231984	2	0.075553185	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K06532|0|hsa:8842|PROM1, AC133, CD133, CORD12, MCDR2, PROML1, RP41, STGD4; prominin 1; K06532 prominin 1 (A)"	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	Prominin	Prominin-1 (Precursor) GN=PROM1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: prominin-1 isoform X1 [Tupaia chinensis] 
ENSG00000007080(CCDC124)	--	57.66326	1024	61.23027908	1151	60.505825	1155	64.13095	1194	64.84121	1176	61.94806	1138	0.96277752	0.190489985	normal	0.980817854	0.009561241	normal	0.980865899	-0.029644632	normal	0.840331581	0.053884736	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1014)	Coiled-coil domain-containing protein 124 GN=CCDC124 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 124 isoform X1 [Leptonychotes weddellii] 
ENSG00000007168(PAFAH1B1)	--	44.05804721	3837	49.22222059	4351	46.31178001	4043	54.00730957	4764	54.15694639	4711	50.03929949	4387	0.962857765	0.281261153	normal	0.991256756	0.093228612	normal	0.990352489	0.109477739	normal	0.426227704	0.159124921	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K16794|0|hsa:5048|PAFAH1B1, LIS1, LIS2, MDCR, MDS, PAFAH; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) (EC:3.1.1.47); K16794 platelet-activating factor acetylhydrolase IB subunit alpha (A)"	Ether lipid metabolism (ko00565)	[S]	Function unknown	"WD domain, G-beta repeat;; Nucleoporin Nup120/160;; LisH;; Eukaryotic translation initiation factor eIF2A;; Nup133 N terminal like"	Platelet-activating factor acetylhydrolase IB subunit alpha {ECO:0000255|HAMAP-Rule:MF_03141} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: platelet-activating factor acetylhydrolase IB subunit alpha [Echinops telfairi]
ENSG00000007171(NOS2)	--	5.071149976	95	1.389088668	43	1.351610571	26	2.374554964	56	1.994410764	65	1.907822548	70	0.446854153	-0.776772546	normal	0.897650051	0.558598242	normal	0.015270201	1.370139144	normal	0.867204305	0.198172093	normal	[PE]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism	Molecular Function: nitric-oxide synthase activity (GO:0004517);; Biological Process: nitric oxide biosynthetic process (GO:0006809);; Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13241|0|hsa:4843|NOS2, HEP-NOS, INOS, NOS, NOS2A; nitric oxide synthase 2, inducible (EC:1.14.13.39); K13241 nitric-oxide synthase, inducible [EC:1.14.13.39] (A)"	Arginine and proline metabolism (ko00330);; Calcium signaling pathway (ko04020);; HIF-1 signaling pathway (ko04066);; Peroxisome (ko04146);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[C]	Energy production and conversion	"Nitric oxide synthase, oxygenase domain;; FAD binding domain;; Flavodoxin;; Oxidoreductase NAD-binding domain"	"Nitric oxide synthase, inducible GN=NOS2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: LOW QUALITY PROTEIN: nitric oxide synthase, inducible-like [Ceratotherium simum simum]"
ENSG00000007174(DNAH9)	--	0.014327709	1	0	0	0	0	0.050038451	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:1770|DNAH9, DNAH17L, DNEL1, DYH9, Dnahc9, HL-20, HL20; dynein, axonemal, heavy chain 9; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Microtubule-binding stalk of dynein motor;; Dynein heavy chain, N-terminal region 1;; P-loop containing dynein motor region D3;; P-loop containing dynein motor region D4;; Hydrolytic ATP binding site of dynein motor region D1;; ATP-binding dynein motor region D5;; Dynein heavy chain, N-terminal region 2;; AAA domain (dynein-related subfamily);; AAA ATPase domain;; AAA domain;; Sigma-54 interaction domain"	"Dynein heavy chain 9, axonemal GN=DNAH9 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 9, axonemal [Ceratotherium simum simum]"
ENSG00000007202(KIAA0100)	--	50.89390891	7553	51.21519075	7820	52.94681123	7781	61.05209403	9280	58.35111078	8603	59.2785169	9204	0.980969828	0.266193835	normal	0.993971356	0.116223238	normal	0.986415303	0.233972105	normal	0.304403149	0.205108307	normal	--	--	--	--	--	[S]	Function unknown	Golgi-body localisation protein domain;; Mitochondrial protein from FMP27;; RNA pol II promoter Fmp27 protein domain	UPF0378 protein KIAA0100 (Precursor) GN=KIAA0100 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: UPF0378 protein KIAA0100 homolog isoform X1 [Galeopterus variegatus]
ENSG00000007237(GAS7)	--	0.456626059	67	0.411279464	44	0.425742314	55	0.158932867	20	0.287757073	36	0.320832512	28	0.000856978	-1.699476889	down	0.972145109	-0.29953155	normal	0.584661973	-0.945216889	normal	0.047899051	-1.002749606	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K18618|0|lve:103080135|GAS7; growth arrest-specific 7; K18618 growth arrest-specific protein 7 (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Fes/CIP4, and EFC/F-BAR homology domain;; Variant SH3 domain;; WW domain;; SH3 domain;; Variant SH3 domain"	Growth arrest-specific protein 7 GN=GAS7 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: growth arrest-specific protein 7 isoform X1 [Equus przewalskii]
ENSG00000007255(TRAPPC6A)	--	54.3981932	543	44.54542762	466	39.48422208	411	22.27308568	216	25.6247701	248	35.22740436	363	2.90E-10	-1.354451236	down	0.000227644	-0.927220385	normal	0.949971869	-0.186728689	normal	0.004552243	-0.799881991	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Transport protein particle (TRAPP) component	Trafficking protein particle complex subunit 6A GN=TRAPPC6A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 6A isoform X2 [Camelus ferus]
ENSG00000007264(MATK)	--	0	0	0.030243645	1	0	0	0.05484233	2	0.561501994	6	0.111617041	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08888|0|hsa:4145|MATK, CHK, CTK, HHYLTK, HYL, HYLTK, Lsk; megakaryocyte-associated tyrosine kinase (EC:2.7.10.2); K08888 megakaryocyte-associated tyrosine kinase [EC:2.7.10.2] (A)"	Neurotrophin signaling pathway (ko04722)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain	Megakaryocyte-associated tyrosine-protein kinase GN=MATK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: megakaryocyte-associated tyrosine-protein kinase [Physeter catodon]
ENSG00000007306(CEACAM7)	--	0	0	0	0	0	0	0	0	0	0	0.136208241	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06499|0|hsa:1087|CEACAM7, CEA, CGM2; carcinoembryonic antigen-related cell adhesion molecule 7; K06499 carcinoembryonic antigen-related cell adhesion molecule (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Carcinoembryonic antigen-related cell adhesion molecule 7 (Precursor) GN=CEACAM7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 6-like [Galeopterus variegatus]
ENSG00000007312(CD79B)	--	0	0	0	0	0	0	0.04102943	1	0.081984464	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06507|1.98036e-156|hsa:974|CD79B, AGM6, B29, IGB; CD79b molecule, immunoglobulin-associated beta; K06507 CD79B antigen (A)"	B cell receptor signaling pathway (ko04662)	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoreceptor tyrosine-based activation motif	B-cell antigen receptor complex-associated protein beta chain (Precursor) GN=CD79B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: B-cell antigen receptor complex-associated protein beta chain isoform X1 [Ailuropoda melanoleuca]
ENSG00000007314(SCN4A)	--	0.069026246	11	0.092944633	15	0	0	0.025150737	4	0.012202671	1	0.03109287	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: voltage-gated sodium channel complex (GO:0001518);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated sodium channel activity (GO:0005248);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04837|0|ggo:101129656|SCN4A; sodium channel protein type 4 subunit alpha; K04837 voltage-gated sodium channel type IV alpha (A)	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Sodium ion transport-associated;; Polycystin cation channel	Sodium channel protein type 4 subunit alpha GN=SCN4A OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel protein type 4 subunit alpha [Odobenus rosmarus divergens]
ENSG00000007341(ST7L)	--	1.525208291	87	1.816315041	81	1.5934171	91	1.764188575	96	1.797084013	89	2.3946624	112	0.96943442	0.109347996	normal	0.968669998	0.112453467	normal	0.945355379	0.286963129	normal	0.757113651	0.176904316	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	ST7 protein	Suppressor of tumorigenicity 7 protein-like GN=ST7L OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: suppressor of tumorigenicity 7 protein-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000007372(PAX6)	--	2.301344956	145	1.693953707	98	2.06682305	128	1.729016946	119	2.75318309	178	2.317559937	136	0.926271866	-0.312264155	normal	0.054493547	0.829962507	normal	0.966803478	0.078274115	normal	0.657499515	0.202471038	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	'Paired box' domain;; Homeobox domain	Paired box protein Pax-6 GN=PAX6 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: paired box protein Pax-6 isoform X5 [Tupaia chinensis]
ENSG00000007376(RPUSD1)	--	18.27547336	643	15.85422468	590	18.65688804	720	20.32296019	761	22.0383555	799	16.63830736	585	0.948194054	0.211779889	normal	0.68494496	0.415136478	normal	0.886134755	-0.307134694	normal	0.694515026	0.113738196	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	--	--	[A]	RNA processing and modification	RNA pseudouridylate synthase	RNA pseudouridylate synthase domain-containing protein 1 GN=RPUSD1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA pseudouridylate synthase domain-containing protein 1 [Galeopterus variegatus]
ENSG00000007384(RHBDF1)	--	12.61994093	606	11.03597324	566	12.760679	611	12.96419401	606	16.22863595	764	12.95354261	630	0.973360041	-0.030754291	normal	0.699685061	0.410397058	normal	0.973581022	0.03580074	normal	0.555452923	0.144817113	normal	[R]	General function prediction only	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[T]	Signal transduction mechanisms	Rhomboid serine protease;; Rhomboid family	Inactive rhomboid protein 1 GN=RHBDF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inactive rhomboid protein 1 isoform X3 [Felis catus]
ENSG00000007392(LUC7L)	--	16.91009993	599	21.1760612	757	19.18178282	700	20.05029598	703	20.13994521	747	18.20729211	700	0.95112732	0.19966332	normal	0.975015568	-0.040530106	normal	0.975462122	-0.008273568	normal	0.890794781	0.043339694	normal	[A]	RNA processing and modification	Molecular Function: mRNA binding (GO:0003729);; Cellular Component: U1 snRNP (GO:0005685);; Biological Process: mRNA splice site selection (GO:0006376);; 	--	--	[A]	RNA processing and modification	LUC7 N_terminus	Putative RNA-binding protein Luc7-like 1 GN=LUC7L OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: putative RNA-binding protein Luc7-like 1 isoform X1 [Pteropus alecto] 
ENSG00000007402(CACNA2D2)	--	0.491897566	58	0.27302545	32	0.228251131	27	0.102918592	12	0.196567803	23	0.172469759	20	5.74E-05	-2.165606973	down	0.970868391	-0.47146724	normal	0.980040026	-0.414202958	normal	0.134357373	-1.109352914	normal	--	--	--	"K04859|0|hsa:9254|CACNA2D2, CACNA2D; calcium channel, voltage-dependent, alpha 2/delta subunit 2; K04859 voltage-dependent calcium channel alpha-2/delta-2 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	VWA N-terminal;; Neuronal voltage-dependent calcium channel alpha 2acd;; Cache domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Voltage-dependent calcium channel subunit delta-2 (Precursor) GN=CACNA2D2 OS=Homo sapiens (Human) PE=1 SV=2	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-2 isoform X1 [Loxodonta africana]
ENSG00000007516(BAIAP3)	--	0.580584611	54	0.187671406	18	0.823303494	20	0.203582704	19	0.575644232	53	0.416512982	35	0.034435995	-1.46449965	normal	0.043976211	1.461899582	normal	0.927231244	0.75539281	normal	0.903207025	0.197765775	normal	--	--	--	K15621|0|pps:100989978|BAIAP3; BAI1-associated protein 3; K15621 BAI1-associated protein 3 (A)	Transcriptional misregulation in cancer (ko05202)	[UT]	"Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	C2 domain;; Munc13 (mammalian uncoordinated) homology domain	BAI1-associated protein 3 GN=BAIAP3 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: BAI1-associated protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000007520(TSR3)	--	60.0772	1050	50.6798	930	54.9641	1009	65.3948	1168	65.5409	1143	61.5985	1080	0.974641838	0.122648475	normal	0.924424018	0.275691236	normal	0.976999799	0.089683751	normal	0.434955362	0.160693192	normal	[S]	Function unknown	--	"K09140|0|hsa:115939|TSR3, C16orf42; TSR3, 20S rRNA accumulation, homolog (S. cerevisiae); K09140 pre-rRNA-processing protein TSR3 (A)"	--	[S]	Function unknown	"Domain of unknown function (DUF367);; Possible Fer4-like domain in RNase L inhibitor, RLI"	Ribosome biogenesis protein TSR3 homolog {ECO:0000255|HAMAP-Rule:MF_03146} OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ribosome biogenesis protein TSR3 homolog isoform X1 [Equus przewalskii]
ENSG00000007541(PIGQ)	--	22.96632407	1035	19.9208914	882	20.9891608	930	22.43443604	1077	22.63071995	1093	23.37170594	1084	0.979919833	0.026516631	normal	0.914261715	0.287572628	normal	0.954667005	0.212450416	normal	0.399865595	0.171592737	normal	--	--	Biological Process: GPI anchor biosynthetic process (GO:0006506);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: phosphatidylinositol N-acetylglucosaminyltransferase activity (GO:0017176);; 	"K03860|0|hsa:9091|PIGQ, GPI1, c407A10.1; phosphatidylinositol glycan anchor biosynthesis, class Q (EC:2.4.1.198); K03860 phosphatidylinositol glycan, class Q (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[MO]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	N-acetylglucosaminyl transferase component (Gpi1)	Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q GN=PIGQ OS=Homo sapiens (Human) PE=1 SV=3	MO	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: phosphatidylinositol N-acetylglucosaminyltransferase subunit Q [Ceratotherium simum simum]
ENSG00000007545(CRAMP1)	--	4.56256023	709	5.71834692	842	6.353250916	868	4.750407	742	5.671188028	828	6.3080796	880	0.975303004	0.034727732	normal	0.97611513	-0.045533552	normal	0.97800784	0.011497145	normal	0.997888878	-0.002116314	normal	--	--	--	--	--	--	--	--	Protein cramped-like GN=CRAMP1L OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein cramped-like [Ceratotherium simum simum]
ENSG00000007866(TEAD3)	--	3.20969722	197	2.6356372	164	3.23475038	203	3.678114825	225	3.613046379	195	2.3150899	141	0.955942004	0.159730867	normal	0.942550966	0.226434968	normal	0.606852093	-0.529318001	normal	0.963294031	-0.029969136	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09448|0|ngi:103739729|Tead3; TEA domain family member 3; K09448 transcriptional enhancer factor (A)	Hippo signaling pathway (ko04390)	[K]	Transcription	TEA/ATTS domain family	Transcriptional enhancer factor TEF-5 GN=TEAD3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcriptional enhancer factor TEF-5 [Vicugna pacos]
ENSG00000007908(SELE)	--	0	0	0.032558854	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06494|0|hsa:6401|SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2; selectin E; K06494 selectin, endothelial cell (A)"	Cell adhesion molecules (CAMs) (ko04514);; TNF signaling pathway (ko04668);; African trypanosomiasis (ko05143);; Malaria (ko05144)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Sushi domain (SCR repeat);; Lectin C-type domain;; EGF-like domain	E-selectin (Precursor) GN=SELE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: E-selectin [Ceratotherium simum simum]
ENSG00000007923(DNAJC11)	--	16.29204783	1143	16.29918184	1154	17.22707634	1218	19.12404545	1339	18.71273506	1296	17.450074	1225	0.963113497	0.197253133	normal	0.972801512	0.145815549	normal	0.981877487	-2.38E-05	normal	0.60784187	0.113730445	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09531|0|hsa:55735|DNAJC11, dJ126A5.1; DnaJ (Hsp40) homolog, subfamily C, member 11; K09531 DnaJ homolog subfamily C member 11 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF3395);; DnaJ domain	DnaJ homolog subfamily C member 11 GN=DNAJC11 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 11 isoform X1 [Mustela putorius furo]
ENSG00000007944(MYLIP)	--	1.718095	68	1.624369393	84	1.266091934	64	1.633975113	80	3.15399633	157	1.936556906	97	0.967123673	0.199474499	normal	0.052082918	0.869256134	normal	0.790901731	0.580406053	normal	0.292787685	0.608059928	normal	--	--	--	"K10637|0|hsa:29116|MYLIP, IDOL, MIR; myosin regulatory light chain interacting protein (EC:6.3.2.-); K10637 E3 ubiquitin-protein ligase MYLIP [EC:6.3.2.19] (A)"	--	--	--	"FERM N-terminal domain;; FERM central domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase MYLIP GN=MYLIP OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: E3 ubiquitin-protein ligase MYLIP [Oryctolagus cuniculus]
ENSG00000007952(NOX1)	--	0.077978156	3	0	0	0	0	0	0	0.028283654	0	0.028820434	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K08008|0|pps:100987167|NOX1; NADPH oxidase 1; K08008 NADPH oxidase (A)	HIF-1 signaling pathway (ko04066);; Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Leukocyte transendothelial migration (ko04670)	[PQ]	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Ferric reductase NAD binding domain;; FAD-binding domain;; Ferric reductase like transmembrane component;; Oxidoreductase FAD-binding domain	NADPH oxidase 1 GN=NOX1 OS=Homo sapiens (Human) PE=1 SV=2	PQ	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: NADPH oxidase 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000007968(E2F2)	--	4.52410012	459	4.33790616	429	4.392503053	448	3.17844912	305	3.48835	335	2.270047423	230	0.107114577	-0.61796023	normal	0.799920962	-0.376736009	normal	8.64E-05	-0.965522197	normal	0.001537879	-0.640661593	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09389|0|hsa:1870|E2F2, E2F-2; E2F transcription factor 2; K09389 transcription factor E2F2 (A)"	Cell cycle (ko04110);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[K]	Transcription	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F2 GN=E2F2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor E2F2 [Ailuropoda melanoleuca]
ENSG00000008018(PSMB1)	--	130.1	1635	124.139	1586	121.256	1547	134.918	1750	130.291	1637	125.351	1595	0.983930873	0.067171007	normal	0.98423551	0.024212269	normal	0.98417018	0.035757359	normal	0.877704068	0.041795327	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02732|8.84918e-179|ptr:473258|PSMB1; proteasome (prosome, macropain) subunit, beta type, 1; K02732 20S proteasome subunit beta 6 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-1 (Precursor) GN=PSMB1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-1 [Dasypus novemcinctus]
ENSG00000008056(SYN1)	--	0.016722875	1	0.020005482	1	0.126298	0	0.090285202	2	0.048464348	2	0.039433901	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Synapsin, ATP binding domain;; Synapsin, N-terminal domain;; Synapsin N-terminal;; RimK-like ATP-grasp domain"	Synapsin-1 GN=SYN1 OS=Homo sapiens (Human) PE=1 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synapsin-1 isoform X1 [Bubalus bubalis]
ENSG00000008083(JARID2)	--	3.493268524	425	3.809961435	468	3.2584701	396	4.904080784	599	5.404245816	658	4.358058438	533	0.532918303	0.462845459	normal	0.515046024	0.468869136	normal	0.687098272	0.418959715	normal	0.018022994	0.452030161	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K11478|0|ptr:462450|JARID2; jumonji, AT rich interactive domain 2; K11478 protein Jumonji (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[R]	General function prediction only	"JmjC domain, hydroxylase;; ARID/BRIGHT DNA binding domain;; jmjN domain;; C5HC2 zinc finger"	Protein Jumonji GN=JARID2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: protein Jumonji isoform X2 [Equus caballus]
ENSG00000008086(CDKL5)	--	5.185863226	824	6.303587969	1229	6.069593104	990	3.893512661	776	3.394444422	705	4.35126683	790	0.970789705	-0.117194714	normal	0.000343703	-0.821862965	normal	0.859361639	-0.333296102	normal	0.100491749	-0.443494163	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08824|0|hsa:6792|CDKL5, EIEE2, ISSX, STK9; cyclin-dependent kinase-like 5 (EC:2.7.11.22); K08824 cyclin-dependent kinase-like [EC:2.7.11.22] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase-like 5 GN=CDKL5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-dependent kinase-like 5 [Equus caballus]
ENSG00000008118(CAMK1G)	--	0.020603582	1	0	0	0	0	0.020761336	1	0.020115347	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08794|0|pps:100980159|CAMK1G; calcium/calmodulin-dependent protein kinase IG; K08794 calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] (A)	Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Calcium/calmodulin-dependent protein kinase type 1G GN=CAMK1G OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type 1G [Physeter catodon]
ENSG00000008128(CDK11A)	--	8.006366821	460	6.47648807	443	6.966711031	458	7.664825089	465	6.91890233	437	6.907876751	462	0.970873311	-0.015184964	normal	0.969025519	-0.040959195	normal	0.971023639	0.004239872	normal	0.967999994	-0.018023655	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08818|0|hsa:728642|CDK11A, CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE, p58GTA; cyclin-dependent kinase 11A (EC:2.7.11.22); K08818 cell division cycle 2-like [EC:2.7.11.22] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 11A GN=CDK11A OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: cyclin-dependent kinase 11B-like isoform X2 [Tupaia chinensis]
ENSG00000008130(NADK)	--	16.6948055	967	13.98494456	850	15.5712559	942	19.4155746	1161	18.30677145	1067	18.77029698	1126	0.947960701	0.23261026	normal	0.896790657	0.306111875	normal	0.939983772	0.248750707	normal	0.149063632	0.260514839	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: NAD+ kinase activity (GO:0003951);; Biological Process: NADP biosynthetic process (GO:0006741);; Biological Process: metabolic process (GO:0008152);; 	"K00858|0|hsa:65220|NADK, dJ283E3.1; NAD kinase (EC:2.7.1.23); K00858 NAD+ kinase [EC:2.7.1.23] (A)"	Nicotinate and nicotinamide metabolism (ko00760)	[G]	Carbohydrate transport and metabolism	ATP-NAD kinase	NAD kinase GN=NADK OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	NAD kinase [Tupaia chinensis]
ENSG00000008226(DLEC1)	--	0.01462968	2	0	0	0	0	0.007385071	1	0.014280538	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Flagellar-associated PapD-like	Deleted in lung and esophageal cancer protein 1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: deleted in lung and esophageal cancer protein 1 [Galeopterus variegatus]
ENSG00000008256(CYTH3)	--	17.78943797	1571	17.5092508	1566	20.20702965	1804	18.49646269	1636	17.34063099	1525	20.47424766	1816	0.984504854	0.027630824	normal	0.982883957	-0.059643159	normal	0.985952985	0.001272359	normal	0.975908526	-0.01018349	normal	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	K18441|0|ggo:101138716|CYTH3; cytohesin-3; K18441 cytohesin (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; PH domain	Cytohesin-3 GN=CYTH3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: cytohesin-3 isoform X2 [Bubalus bubalis]
ENSG00000008277(ADAM22)	--	3.54891636	351	2.68553622	334	2.814265379	385	1.008424722	123	1.769782675	138	1.289224018	148	8.70E-11	-1.531779044	down	1.87E-07	-1.28723554	down	3.33E-09	-1.378483506	down	6.75E-11	-1.407830029	down	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K16068|0|pps:100973794|ADAM22; ADAM metallopeptidase domain 22; K16068 disintegrin and metalloproteinase domain-containing protein 22 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Reprolysin family propeptide;; Disintegrin;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 22 (Precursor) GN=ADAM22 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 22 isoform X10 [Mustela putorius furo] 
ENSG00000008282(SYPL1)	--	84.69013739	2089	87.58838854	2151	78.60846364	1893	104.2679175	2606	88.08469903	2170	90.87034953	2241	0.940919691	0.288002368	normal	0.987222744	-0.008732927	normal	0.962490581	0.235004056	normal	0.362357454	0.172340924	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Membrane-associating domain	Synaptophysin-like protein 1 GN=SYPL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: synaptophysin-like protein 1 [Galeopterus variegatus]
ENSG00000008283(CYB561)	--	21.17451802	911	20.60401218	974	19.58555587	947	23.93515226	1133	29.22226548	1293	22.04229032	1007	0.917096338	0.283363429	normal	0.770425955	0.386779274	normal	0.976826634	0.080211678	normal	0.155533432	0.256219078	normal	--	--	--	K08360|8.71772e-146|ptr:454783|CYB561; cytochrome b-561; K08360 cytochrome b-561 (A)	--	[C]	Energy production and conversion	Eukaryotic cytochrome b561	Cytochrome b561 GN=CYB561 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: cytochrome b561 [Loxodonta africana] 
ENSG00000008294(SPAG9)	--	29.4258059	3810	30.79277298	4016	27.68386081	3674	32.95620347	4248	29.93970522	3799	32.66728703	4366	0.989199025	0.126112328	normal	0.989895303	-0.1015268	normal	0.974532447	0.240578116	normal	0.703841997	0.088936583	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	JNK_SAPK-associated protein-1	C-Jun-amino-terminal kinase-interacting protein 4 GN=SPAG9 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: C-Jun-amino-terminal kinase-interacting protein 4 isoform X1 [Galeopterus variegatus]
ENSG00000008300(CELSR3)	--	5.297621	1283	5.258798	1295	5.080629	1265	2.576605	624	2.921156	705	3.804374	935	7.55E-08	-1.068857896	down	3.56E-05	-0.89724045	normal	0.569324627	-0.443771042	normal	2.72E-07	-0.783369531	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04602|0|hsa:1951|CELSR3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2, RESDA1; cadherin, EGF LAG seven-pass G-type receptor 3; K04602 cadherin EGF LAG seven-pass G-type receptor 3 (A)"	--	[T]	Signal transduction mechanisms	Cadherin domain;; 7 transmembrane receptor (Secretin family);; Laminin G domain;; Domain of unknown function (DUF3497);; Laminin G domain;; EGF-like domain;; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain;; Laminin EGF-like (Domains III and V)	Cadherin EGF LAG seven-pass G-type receptor 3 (Precursor) GN=CELSR3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cadherin EGF LAG seven-pass G-type receptor 3 [Galeopterus variegatus]
ENSG00000008311(AASS)	--	0.125634825	7	0.088877584	5	0	0	0.10687966	6	0.246466307	13	0.143003226	8	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K14157|0|hsa:10157|AASS, LKR/SDH, LKRSDH, LORSDH; aminoadipate-semialdehyde synthase (EC:1.5.1.8 1.5.1.9); K14157 alpha-aminoadipic semialdehyde synthase [EC:1.5.1.8 1.5.1.9] (A)"	Lysine degradation (ko00310)	[E]	Amino acid transport and metabolism	"Saccharopine dehydrogenase;; Alanine dehydrogenase/PNT, C-terminal domain;; Alanine dehydrogenase/PNT, N-terminal domain"	Saccharopine dehydrogenase (Precursor) GN=AASS OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	"PREDICTED: alpha-aminoadipic semialdehyde synthase, mitochondrial [Tupaia chinensis]"
ENSG00000008323(PLEKHG6)	--	1.002603673	40	0.579441295	34	0.696139565	33	0.799285661	28	0.630832435	23	0.819646001	27	0.958119571	-0.521341282	normal	0.96078137	-0.555122597	normal	0.980316491	-0.2834162	normal	0.507246378	-0.477618398	normal	[T]	Signal transduction mechanisms	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Pleckstrin homology domain-containing family G member 6 GN=PLEKHG6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family G member 6 [Equus caballus]
ENSG00000008324(SS18L2)	--	14.820915	142	12.1447	116	14.113382	135	16.780276	163	15.61755	151	15.76854	155	0.957985755	0.166466746	normal	0.903332665	0.354931399	normal	0.955295562	0.189039651	normal	0.579803927	0.233815831	normal	--	--	--	--	--	[K]	Transcription	SSXT protein (N-terminal region)	SS18-like protein 2 GN=SS18L2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: SS18-like protein 2 [Loxodonta africana]
ENSG00000008382(MPND)	--	4.592757843	116	3.627370401	118	4.528149956	135	3.928860891	85	5.14158432	112	2.791548852	76	0.854307829	-0.472085306	normal	0.965855971	-0.095458747	normal	0.134927183	-0.824698504	normal	0.255560588	-0.45577585	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Prokaryotic homologs of the JAB domain	MPN domain-containing protein GN=MPND OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: MPN domain-containing protein [Lipotes vexillifer]
ENSG00000008394(MGST1)	--	426.6916579	4651	486.6978321	5208	491.0272095	5300	698.7382591	7641	593.749765	6421	780.7295502	8527	0.01001178	0.685209998	normal	0.970783537	0.280568506	normal	0.013129003	0.67760062	normal	0.001924834	0.554618932	normal	--	--	--	K00799|5.79621e-40|pps:100983759|MGST1; microsomal glutathione S-transferase 1; K00799 glutathione S-transferase [EC:2.5.1.18] (A)	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	--	--	--	Microsomal glutathione S-transferase 1 GN=MGST1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: microsomal glutathione S-transferase 1-like [Equus przewalskii]
ENSG00000008405(CRY1)	--	10.74761001	551	12.869476	671	12.815742	662	11.46935889	596	11.892808	614	12.304945	638	0.970080265	0.082207318	normal	0.96265951	-0.149149115	normal	0.973018222	-0.061423293	normal	0.878434424	-0.048707651	normal	[L]	"Replication, recombination and repair"	--	K02295|0|nle:100582392|CRY1; cryptochrome 1 (photolyase-like); K02295 cryptochrome (A)	Circadian rhythm (ko04710)	[LT]	"Replication, recombination and repair;; Signal transduction mechanisms"	FAD binding domain of DNA photolyase;; DNA photolyase	Cryptochrome-1 GN=CRY1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cryptochrome-1 [Leptonychotes weddellii]
ENSG00000008438(PGLYRP1)	--	0	0	0	0	0	0	0.111517	1	0.112186	0	0.112487	1	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: N-acetylmuramoyl-L-alanine amidase activity (GO:0008745);; Biological Process: peptidoglycan catabolic process (GO:0009253);; 	"K01446|6.43969e-134|hsa:8993|PGLYRP1, PGLYRP, PGRP, PGRP-S, PGRPS, TAG7, TNFSF3L; peptidoglycan recognition protein 1; K01446 N-acetylmuramoyl-L-alanine amidase [EC:3.5.1.28] (A)"	--	--	--	N-acetylmuramoyl-L-alanine amidase	Peptidoglycan recognition protein 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: peptidoglycan recognition protein 1 [Galeopterus variegatus]
ENSG00000008441(NFIX)	--	3.110416615	313	1.997468463	205	2.344400348	242	4.125619706	445	4.49582652	476	3.414641242	364	0.539812217	0.474846775	normal	2.53E-07	1.187996047	up	0.252878045	0.577676789	normal	0.001530579	0.735987031	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09171|0|umr:103682141|NFIX; nuclear factor I/X (CCAAT-binding transcription factor); K09171 nuclear factor I/X (A)	--	[K]	Transcription	CTF/NF-I family transcription modulation region;; Nuclear factor I protein pre-N-terminus;; MH1 domain	Nuclear factor 1 X-type GN=NFIX OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear factor 1 X-type isoform X1 [Physeter catodon]
ENSG00000008513(ST3GAL1)	--	5.499045009	798	4.218557701	616	4.482392401	653	6.422323143	920	7.442237954	1065	7.428346523	1028	0.962322433	0.174100481	normal	0.001849356	0.766975705	normal	0.027553538	0.645193093	normal	0.001027775	0.52276652	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K00780|0|hsa:6482|ST3GAL1, Gal-NAc6S, SIAT4A, SIATFL, ST3GalA, ST3GalA.1, ST3GalIA, ST3GalIA,1, ST3O; ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (EC:2.4.99.4); K00780 beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4A) [EC:2.4.99.4] (A)"	Mucin type O-Glycan biosynthesis (ko00512);; Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - globo series (ko00603);; Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 GN=ST3GAL1 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 [Oryctolagus cuniculus]"
ENSG00000008516(MMP25)	--	0.516718	32	0.222659	14	0.633446	40	0.46872	29	0.562186	35	0.349098	22	0.983597158	-0.164547883	normal	0.621942439	1.215032357	normal	0.872198927	-0.827997281	normal	0.999953667	-0.020572304	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K08003|0|hsa:64386|MMP25, MMP-25, MMP20, MMP20A, MMPL1, MT-MMP_6, MT-MMP6, MT6-MMP, MT6MMP, MTMMP6; matrix metallopeptidase 25; K08003 matrix metalloproteinase-25 (membrane-inserted) [EC:3.4.24.-] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	Matrix metalloproteinase-25 (Precursor) GN=MMP25 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: matrix metalloproteinase-25 [Pteropus alecto]
ENSG00000008517(IL32)	--	2.660707909	45	1.924031943	34	2.481101061	40	14.88250843	245	12.39970571	206	7.274342514	117	0	2.375140013	up	0	2.52591428	up	4.68E-05	1.505338779	up	0.000116643	2.231824173	up	--	--	Biological Process: immune response (GO:0006955);; 	--	--	--	--	Interleukin 32	Interleukin-32 (Precursor) GN=IL32 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: interleukin 32 [Vicugna pacos]
ENSG00000008710(PKD1)	--	20.386257	4109	20.748279	4125	20.636061	4110	13.748978	2703	13.267705	2652	17.96801	3353	0.028820043	-0.634763083	normal	0.020014379	-0.658436232	normal	0.948146933	-0.30185416	normal	0.000311628	-0.523965457	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K04985|0|hsa:5310|PKD1, PBP, Pc-1, TRPP1; polycystic kidney disease 1 (autosomal dominant); K04985 polycystin 1 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PKD domain;; Polycystin cation channel;; REJ domain;; PLAT/LH2 domain;; Leucine rich repeat;; WSC domain;; Lectin C-type domain;; Y_Y_Y domain;; Latrophilin/CL-1-like GPS domain;; Leucine rich repeat N-terminal domain	Polycystin-1 (Precursor) GN=PKD1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: polycystin-1 [Galeopterus variegatus]
ENSG00000008735(MAPK8IP2)	--	3.266759911	215	4.358145367	292	3.1365	214	1.326447931	82	2.023768903	129	2.123573784	149	4.89E-07	-1.404571206	down	5.47E-06	-1.190482472	down	0.595275338	-0.526109551	normal	0.001420594	-1.021787335	down	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04435|0|hsa:23542|MAPK8IP2, IB-2, IB2, JIP2, PRKM8IPL; mitogen-activated protein kinase 8 interacting protein 2; K04435 mitogen-activated protein kinase 8 interacting protein 2 (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; Variant SH3 domain;; SH3 domain	C-Jun-amino-terminal kinase-interacting protein 2 GN=MAPK8IP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: c-Jun-amino-terminal kinase-interacting protein 2 [Ceratotherium simum simum]
ENSG00000008838(MED24)	--	25.34455305	1538	27.65145844	1637	24.11948145	1570	25.63889489	1601	26.42883007	1695	26.52583933	1583	0.98429265	0.027059047	normal	0.984508939	0.028778267	normal	0.984585215	0.003601799	normal	0.954036963	0.018957592	normal	--	--	--	K15167|0|pps:100969630|MED24; mediator complex subunit 24; K15167 mediator of RNA polymerase II transcription subunit 24 (A)	Thyroid hormone signaling pathway (ko04919)	--	--	Mediator complex subunit 24 N-terminal	Mediator of RNA polymerase II transcription subunit 24 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 24 isoformX1 [Equus caballus]
ENSG00000008853(RHOBTB2)	--	5.023134795	583	6.600264757	792	5.622832235	666	8.896931705	1028	10.83495367	1293	17.9814386	2094	0.000926121	0.785861245	normal	0.0116371	0.684690564	normal	0	1.642157622	up	0.06648269	1.093952732	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07868|0|hsa:23221|RHOBTB2, DBC2; Rho-related BTB domain containing 2; K07868 Rho-related BTB domain-containing protein 1/2 (A)"	Ubiquitin mediated proteolysis (ko04120)	[R]	General function prediction only	BTB/POZ domain;; Ras family;; Miro-like protein	Rho-related BTB domain-containing protein 2 GN=RHOBTB2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: rho-related BTB domain-containing protein 2 isoform X2 [Sus scrofa]
ENSG00000008869(HEATR5B)	--	6.9878415	819	7.7809279	907	6.728636439	775	5.220847703	606	4.65951499	537	6.187675497	725	0.493237312	-0.464360848	normal	0.00176071	-0.7759054	normal	0.971459454	-0.104296294	normal	0.009737818	-0.441925057	normal	--	--	--	--	--	[S]	Function unknown	HEAT repeats;; HEAT repeat	HEAT repeat-containing protein 5B GN=HEATR5B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: HEAT repeat-containing protein 5B isoform X2 [Oryctolagus cuniculus]
ENSG00000008952(SEC62)	--	36.89475841	2642	44.20781753	2989	38.46304372	2663	36.632625	2659	37.0314055	2634	35.34161954	2404	0.98919141	-0.021566451	normal	0.97639351	-0.20372422	normal	0.982036608	-0.1558138	normal	0.535801136	-0.129365254	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein transporter activity (GO:0008565);; Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of membrane (GO:0016021);; 	K12275|1.68811e-149|pbi:103064886|SEC62; SEC62 homolog (S. cerevisiae); K12275 translocation protein SEC62 (A)	Protein export (ko03060);; Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Translocation protein Sec62	Translocation protein SEC62 GN=SEC62 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: translocation protein SEC62 isoform X1 [Sorex araneus] 
ENSG00000008988(RPS20)	--	1054.314831	7672	1072.59351	8067	1026.826338	7837	1105.811627	8694	1111.833748	8134	1057.227346	8088	0.992945108	0.149556964	normal	0.995367839	-0.009492051	normal	0.995334896	0.037182995	normal	0.830963033	0.058312625	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02969|6.35514e-99|ptr:464184|RPS20; ribosomal protein S20; K02969 small subunit ribosomal protein S20e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S10p/S20e	40S ribosomal protein S20 GN=RPS20 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S20-like [Elephantulus edwardii]
ENSG00000009307(CSDE1)	--	131.4620932	8072	144.2893292	8893	141.6464181	8449	150.2927179	9489	144.5545385	8762	138.9995951	8788	0.990140676	0.202462047	normal	0.995523771	-0.042829191	normal	0.995537228	0.048454325	normal	0.798964668	0.067947884	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	'Cold-shock' DNA-binding domain;; S1-like;; SUZ-C motif;; Copper binding periplasmic protein CusF	Cold shock domain-containing protein E1 GN=CSDE1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cold shock domain-containing protein E1 isoform X1 [Panthera tigris altaica] 
ENSG00000009335(UBE3C)	--	35.08272	3038	36.548776	3188	35.31564	3052	41.787935	3620	42.806743	3679	37.98402	3281	0.975543663	0.221932643	normal	0.982143105	0.185153675	normal	0.98868212	0.096043282	normal	0.385101543	0.167962341	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	"K10589|0|hsa:9690|UBE3C, HECTH2; ubiquitin protein ligase E3C; K10589 ubiquitin-protein ligase E3 C [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase)	Ubiquitin-protein ligase E3C GN=UBE3C OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-protein ligase E3C [Oryctolagus cuniculus]
ENSG00000009413(REV3L)	--	4.134989857	835	4.832162748	983	4.607725371	834	4.48057355	850	4.498238461	867	4.784241587	936	0.977539052	-0.005136253	normal	0.956080435	-0.202254399	normal	0.966267895	0.157899303	normal	0.953328303	-0.020545145	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	"K02350|0|pps:100969784|REV3L; REV3-like, polymerase (DNA directed), zeta, catalytic subunit; K02350 DNA polymerase zeta [EC:2.7.7.7] (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	"DNA polymerase family B;; DNA polymerase family B, exonuclease domain;; C4-type zinc-finger of DNA polymerase delta"	DNA polymerase zeta catalytic subunit GN=REV3L OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase zeta catalytic subunit isoformX1 [Canis lupus familiaris]
ENSG00000009694(TENM1)	--	0.00842238	2	0.02104036	5	0.0083854	1	0.01258632	3	0.0285618	6	0.00417627	1	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Biological Process: signal transduction (GO:0007165);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Teneurin Intracellular Region;; GHH signature containing HNH/Endo VII superfamily nuclease toxin;; EGF-like domain;; NHL repeat;; RHS Repeat;; Human growth factor-like EGF	Teneurin C-terminal-associated peptide GN=TENM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: teneurin-1 [Oryctolagus cuniculus]
ENSG00000009709(PAX7)	--	0.080226002	7	0.046125561	6	0.126130094	6	0.4837893	37	1.1557022	84	0.717226921	62	0.008282504	2.147071159	up	8.80E-13	3.489728235	up	1.72E-08	3.072353441	up	2.74E-05	3.248012551	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09381|0|ggo:101135934|PAX7; paired box protein Pax-7 isoform 1; K09381 paired box protein 3/7 (A)	--	[K]	Transcription	'Paired box' domain;; Homeobox domain;; Paired box protein 7;; Homeodomain-like domain;; Homeobox KN domain	Paired box protein Pax-7 GN=PAX7 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: paired box protein Pax-7 isoform 1 [Odobenus rosmarus divergens]
ENSG00000009724(MASP2)	--	0.244814	11	0.220575	10	0.174153	7	0.488246	22	0.129752	5	0.154436	7	0.959857696	0.88083056	normal	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: proteolysis (GO:0006508);; 	"K03993|0|hsa:10747|MASP2, MAP19, MASP-2, MASP1P1, sMAP; mannan-binding lectin serine peptidase 2 (EC:3.4.21.104); K03993 mannan-binding lectin serine protease 2 [EC:3.4.21.104] (A)"	Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150)	[E]	Amino acid transport and metabolism	Trypsin;; CUB domain;; Sushi domain (SCR repeat);; Calcium-binding EGF domain	Mannan-binding lectin serine protease 2 B chain (Precursor) GN=MASP2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mannan-binding lectin serine protease 2 [Galeopterus variegatus]
ENSG00000009780(FAM76A)	--	2.788780831	124	4.155646	163	3.48023325	152	2.456270306	126	2.294541442	114	2.712269376	128	0.969067258	-0.007654564	normal	0.681273459	-0.531336833	normal	0.942833069	-0.253467348	normal	0.509389078	-0.275654654	normal	--	--	--	--	--	[S]	Function unknown	--	Protein FAM76A GN=FAM76A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM76A isoform 1 [Odobenus rosmarus divergens]
ENSG00000009830(POMT2)	--	13.67984191	1052	13.85525409	1130	14.979808	1119	12.33573088	1044	14.344737	1080	13.52508142	1205	0.97945235	-0.041783997	normal	0.977449863	-0.086599454	normal	0.977681328	0.098403488	normal	0.982012688	-0.008544874	normal	--	--	Molecular Function: mannosyltransferase activity (GO:0000030);; Biological Process: protein O-linked glycosylation (GO:0006493);; Cellular Component: membrane (GO:0016020);; 	"K00728|0|hsa:29954|POMT2, LGMD2N, MDDGA2, MDDGB2, MDDGC2; protein-O-mannosyltransferase 2 (EC:2.4.1.109); K00728 dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] (A)"	Other types of O-glycan biosynthesis (ko00514)	[O]	"Posttranslational modification, protein turnover, chaperones"	Dolichyl-phosphate-mannose-protein mannosyltransferase;; MIR domain	Protein O-mannosyl-transferase 2 GN=POMT2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein O-mannosyl-transferase 2 [Galeopterus variegatus]
ENSG00000009844(VTA1)	--	24.07395995	908	27.07964343	997	23.40397039	858	23.82126886	915	25.13468322	933	20.90726209	755	0.97832259	-0.019719579	normal	0.97295773	-0.116959543	normal	0.95684778	-0.192430609	normal	0.653781397	-0.107956034	normal	--	--	--	K12199|0|ptr:463033|VTA1; vesicle (multivesicular body) trafficking 1; K12199 vacuolar protein sorting-associated protein VTA1 (A)	Endocytosis (ko04144)	[S]	Function unknown	Vta1 like	Vacuolar protein sorting-associated protein VTA1 homolog GN=VTA1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein VTA1 homolog isoform 1 [Orcinus orca]
ENSG00000009950(MLXIPL)	--	2.410048462	163	1.875668904	99	1.739492753	100	0.40157098	26	0.85590594	60	0.786830274	51	7.77E-16	-2.608819837	down	0.516966723	-0.729427326	normal	0.106510561	-0.959037699	normal	0.005961702	-1.421440979	down	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09113|0|hsa:51085|MLXIPL, CHREBP, MIO, MONDOB, WBSCR14, WS-bHLH, bHLHd14; MLX interacting protein-like; K09113 MAX-like protein X (A)"	Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Carbohydrate-responsive element-binding protein GN=MLXIPL OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: carbohydrate-responsive element-binding protein isoform X1 [Galeopterus variegatus]
ENSG00000009954(BAZ1B)	--	27.95750516	4269	33.04389857	5063	31.46308583	4779	32.89662257	5028	32.36735065	4909	30.10791215	4583	0.983412992	0.205186122	normal	0.992564412	-0.065969863	normal	0.992346415	-0.068685727	normal	0.9508736	0.019773903	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	"K11658|0|hsa:9031|BAZ1B, WBSCR10, WBSCR9, WSTF; bromodomain adjacent to zinc finger domain, 1B (EC:2.7.10.2); K11658 bromodomain adjacent to zinc finger domain protein 1B (A)"	--	[B]	Chromatin structure and dynamics	"ATP-utilising chromatin assembly and remodelling N-terminal;; Bromodomain;; PHD-finger;; WSTF, HB1, Itc1p, MBD9 motif 2;; WSTF, HB1, Itc1p, MBD9 motif 1;; WSTF, HB1, Itc1p, MBD9 motif 3"	Tyrosine-protein kinase BAZ1B GN=BAZ1B OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: tyrosine-protein kinase BAZ1B [Galeopterus variegatus]
ENSG00000010017(RANBP9)	--	10.26518	614	9.345009	560	9.931642	586	10.325698	619	11.276249	665	10.21289	617	0.973801269	-0.019083949	normal	0.940570576	0.225940481	normal	0.971869339	0.065912597	normal	0.747429943	0.090042074	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	CTLH/CRA C-terminal to LisH motif domain;; SPRY domain;; LisH	Ran-binding protein 9 GN=RANBP9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ran-binding protein 9 [Orycteropus afer afer]
ENSG00000010030(ETV7)	--	0.042672869	1	0	0	0	0	0.038470946	1	0.069584281	1	0.035276253	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K03211|0|ptr:747854|ETV7; ets variant 7; K03211 ETS translocation variant 6/7 (A)	Dorso-ventral axis formation (ko04320);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	Transcription factor ETV7 GN=ETV7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor ETV7 isoform X1 [Galeopterus variegatus]
ENSG00000010072(SPRTN)	--	9.205476	528	7.721319	443	8.6808181	532	7.107670697	440	9.64549688	532	7.811373	445	0.897565545	-0.292931328	normal	0.930804266	0.241938455	normal	0.918411214	-0.265087271	normal	0.716359731	-0.105861449	normal	--	--	--	--	--	[S]	Function unknown	SprT-like family	SprT-like domain-containing protein Spartan GN=SPRTN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: sprT-like domain-containing protein Spartan [Trichechus manatus latirostris]
ENSG00000010165(METTL13)	--	18.987138	1225	20.8203	1376	19.198814	1257	18.859763	1231	19.86726	1261	21.495685	1381	0.981695942	-0.023753532	normal	0.973741621	-0.147169722	normal	0.976605453	0.127291075	normal	0.963418202	-0.015333757	normal	--	--	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[E]	Amino acid transport and metabolism	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Spermine/spermidine synthase;; Methyltransferase domain;; Methyltransferase small domain;; ubiE/COQ5 methyltransferase family	Methyltransferase-like protein 13 GN=METTL13 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: methyltransferase-like protein 13 isoform X1 [Oryctolagus cuniculus]
ENSG00000010219(DYRK4)	--	5.213631087	212	5.248002864	175	4.721677825	194	7.082319057	311	7.342169137	270	5.649240275	246	0.489299553	0.518896483	normal	0.300548943	0.599973765	normal	0.887314824	0.332006821	normal	0.062240083	0.487473314	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K18669|0|mcf:102122117|DYRK4, RAD51AP1; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4; K18669 dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Dual specificity tyrosine-phosphorylation-regulated kinase 4 GN=DYRK4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 4 isoform X3 [Canis lupus familiaris]
ENSG00000010244(ZNF207)	--	79.90536353	4151	93.96223187	4704	91.10290371	4574	100.4499951	4963	104.5226932	4957	79.70078182	4287	0.979616307	0.226844394	normal	0.992589269	0.054135686	normal	0.991025873	-0.101744636	normal	0.816629057	0.059696807	normal	--	--	--	--	--	[R]	General function prediction only	--	BUB3-interacting and GLEBS motif-containing protein ZNF207 GN=ZNF207 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	hypothetical protein PANDA_000157 [Ailuropoda melanoleuca]
ENSG00000010256(UQCRC1)	--	70.7328	2591	68.7453	2580	74.9081	2818	76.0917	2808	81.5788	2973	80.3643	2954	0.987772144	0.085153146	normal	0.979576627	0.183021837	normal	0.989188848	0.059675491	normal	0.623059952	0.107934257	normal	[R]	General function prediction only	--	K00414|0|ptr:460348|UQCRC1; ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2); K00414 ubiquinol-cytochrome c reductase core subunit 1 (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[O]	"Posttranslational modification, protein turnover, chaperones"	Insulinase (Peptidase family M16);; Peptidase M16 inactive domain	"Cytochrome b-c1 complex subunit 1, mitochondrial (Precursor) GN=UQCRC1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: cytochrome b-c1 complex subunit 1, mitochondrial isoform X2 [Equus przewalskii]"
ENSG00000010270(STARD3NL)	--	37.404251	868	40.23077588	929	36.4402267	854	41.86538345	981	39.0900576	871	40.76425728	913	0.968923507	0.145483501	normal	0.972283018	-0.11424033	normal	0.975004407	0.08793672	normal	0.894834207	0.039187135	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Cholesterol-capturing domain	MLN64 N-terminal domain homolog GN=STARD3NL OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: MLN64 N-terminal domain homolog [Condylura cristata]
ENSG00000010278(CD9)	--	185.22334	2570	169.87317	2438	172.5660904	2429	163.60709	2326	156.57974	2268	196.603138	2757	0.979198031	-0.174639717	normal	0.983735151	-0.125623228	normal	0.980033923	0.174343389	normal	0.890265455	-0.037525968	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06460|1.59045e-134|pps:100984689|CD9; CD9 molecule; K06460 CD9 antigen (A)	Hematopoietic cell lineage (ko04640)	[R]	General function prediction only	Tetraspanin family	CD9 antigen GN=CD9 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: CD9 antigen [Pteropus alecto] 
ENSG00000010292(NCAPD2)	--	52.27596	5630	44.81571268	4946	52.113819	5713	47.59449102	5122	46.537939	5020	43.04732728	4691	0.9889316	-0.167212066	normal	0.993182903	-1.43E-06	normal	0.96297473	-0.292558861	normal	0.446336076	-0.156360612	normal	--	--	--	"K06677|0|hsa:9918|NCAPD2, CAP-D2, CNAP1, hCAP-D2; non-SMC condensin I complex, subunit D2; K06677 condensin complex subunit 1 (A)"	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	"non-SMC mitotic condensation complex subunit 1;; non-SMC mitotic condensation complex subunit 1, N-term;; Adaptin N terminal region"	Condensin complex subunit 1 GN=NCAPD2 OS=Homo sapiens (Human) PE=1 SV=3	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: condensin complex subunit 1 [Ceratotherium simum simum]
ENSG00000010295(IFFO1)	--	0.838155704	38	0.773286691	36	0.785228246	36	1.385717136	63	1.343310048	60	0.91835327	42	0.839933321	0.677064372	normal	0.834512428	0.692780105	normal	0.978510884	0.206079395	normal	0.326102006	0.562641367	normal	--	--	--	--	--	--	--	Intermediate filament protein	Intermediate filament family orphan 1 GN=IFFO1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: intermediate filament family orphan 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000010310(GIPR)	--	1.972584886	92	1.209812128	42	0.839421383	39	1.049477851	58	1.697285732	67	0.475050758	29	0.660094118	-0.681936449	normal	0.84689134	0.634122141	normal	0.969459186	-0.416900411	normal	0.883261986	-0.191212164	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04580|0|hsa:2696|GIPR, PGQTL2; gastric inhibitory polypeptide receptor; K04580 gastric inhibitory polypeptide receptor (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Gastric inhibitory polypeptide receptor (Precursor) GN=GIPR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gastric inhibitory polypeptide receptor isoform X1 [Galeopterus variegatus]
ENSG00000010318(PHF7)	--	3.768186187	143	2.909731263	109	3.084170871	118	2.857117966	104	2.08515543	77	3.059595366	111	0.798237013	-0.484135862	normal	0.824298658	-0.514290018	normal	0.967267889	-0.095259647	normal	0.392858726	-0.362735903	normal	--	--	--	--	--	[K]	Transcription	PHD-like zinc-binding domain;; PHD-zinc-finger like domain	PHD finger protein 7 GN=PHF7 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: PHD finger protein 7 isoformX1 [Canis lupus familiaris]
ENSG00000010319(SEMA3G)	--	0.077874041	8	0.327927383	14	0.187043563	19	0.058283126	6	0.0761574	7	0.07744003	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06840|0|hsa:56920|SEMA3G, sem2; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G; K06840 semaphorin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-3G (Precursor) GN=SEMA3G OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-3G isoform X1 [Equus caballus]
ENSG00000010322(NISCH)	--	8.912211253	1326	9.2008826	1252	9.247724	1336	6.781695398	933	8.9609383	1234	8.789310749	1306	0.194229235	-0.537217697	normal	0.981000393	-0.0422673	normal	0.982181535	-0.041009601	normal	0.375580777	-0.192536192	normal	[S]	Function unknown	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	PX domain;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat	Nischarin GN=NISCH OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: nischarin isoform 1 [Ceratotherium simum simum]
ENSG00000010327(STAB1)	--	0	0	0	0	0	0	0.006431817	1	0	0	0.019061875	3	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	--	--	[T]	Signal transduction mechanisms	Fasciclin domain;; EGF domain;; Extracellular link domain	Stabilin-1 (Precursor) GN=STAB1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: stabilin-1 [Ceratotherium simum simum]
ENSG00000010361(FUZ)	--	11.976888	313	9.211749	247	9.585214	244	10.446282	262	11.62006182	297	11.69685724	296	0.909353972	-0.285891755	normal	0.930978019	0.243166038	normal	0.920582997	0.26890919	normal	0.870032947	0.067751553	normal	--	--	--	--	--	--	--	--	Protein fuzzy homolog GN=FUZ OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein fuzzy homolog isoform X1 [Erinaceus europaeus]
ENSG00000010379(SLC6A13)	--	0	0	0.12446	2	0.312127	4	0.0625886	1	0.188101	2	0.318879	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05039|0|ptr:100614945|SLC6A13; solute carrier family 6 (neurotransmitter transporter), member 13; K05039 solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium- and chloride-dependent GABA transporter 2 GN=SLC6A13 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: sodium- and chloride-dependent GABA transporter 2 isoform X2 [Pteropus alecto]
ENSG00000010404(IDS)	--	57.40456868	5242	68.51984711	6379	61.55824663	5714	80.64391161	7638	66.2383595	6146	84.81222092	7733	0.432127757	0.512120302	normal	0.993624592	-0.075090931	normal	0.802547796	0.428137974	normal	0.11957622	0.290466996	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K01136|0|hsa:3423|IDS, MPS2, SIDS; iduronate 2-sulfatase (EC:3.1.6.13); K01136 iduronate 2-sulfatase [EC:3.1.6.13] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	[R]	General function prediction only	Sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	Iduronate 2-sulfatase 14 kDa chain (Precursor) GN=IDS OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: iduronate 2-sulfatase isoform X1 [Oryctolagus cuniculus]
ENSG00000010438(PRSS3)	--	0.377188037	4	0	0	0.468287933	6	6.71395589	100	8.827751721	124	3.4252947	54	0	4.170570802	up	0	6.364405435	up	7.66E-07	2.878139081	up	4.21E-08	4.776964907	up	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01312|0|pps:100995726|PRSS3; protease, serine, 3; K01312 trypsin [EC:3.4.21.4] (A)"	Neuroactive ligand-receptor interaction (ko04080);; Pancreatic secretion (ko04972);; Protein digestion and absorption (ko04974);; Influenza A (ko05164)	[E]	Amino acid transport and metabolism	Trypsin	Trypsin-3 (Precursor) GN=PRSS3 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: trypsin-2 [Equus przewalskii]
ENSG00000010539(ZNF200)	--	3.677467067	198	4.197954096	200	3.912976793	178	3.714866105	205	4.2498931	218	3.694119875	191	0.966866494	0.019145215	normal	0.96162965	0.102161532	normal	0.963972667	0.092643982	normal	0.883493494	0.07062698	normal	[R]	General function prediction only	--	K09228|0|hsa:7752|ZNF200; zinc finger protein 200; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 200 GN=ZNF200 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 200 isoform X2 [Camelus ferus] 
ENSG00000010610(CD4)	--	0.103663673	7	0.102040228	7	0.152147882	9	0.045638067	3	0.105425506	5	0.093588821	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell adhesion (GO:0007155);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06454|0|hsa:920|CD4, CD4mut; CD4 molecule; K06454 CD4 antigen (A)"	Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Hematopoietic cell lineage (ko04640);; T cell receptor signaling pathway (ko04660);; Primary immunodeficiency (ko05340)	--	--	"CD4, extracellular;; Immunoglobulin C2-set domain;; T cell CD4 receptor C terminal region;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Natural killer cell receptor 2B4"	T-cell surface glycoprotein CD4 (Precursor) GN=CD4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: T-cell surface glycoprotein CD4 [Galeopterus variegatus]
ENSG00000010626(LRRC23)	--	68.14107893	3029	71.24260506	3151	71.33311355	3187	58.6867506	2584	38.35320027	1672	53.39180524	2378	0.960625614	-0.259924836	normal	4.31E-06	-0.935034586	normal	0.691223021	-0.430504377	normal	0.004060232	-0.519312022	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 23 GN=LRRC23 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 23 isoform X1 [Galeopterus variegatus] 
ENSG00000010671(BTK)	--	0	0	0.0538598	3	0	0	0	0	0	0	0.053810085	3	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	K07370|0|umr:103672987|BTK; Bruton agammaglobulinemia tyrosine kinase; K07370 Bruton agammaglobulinemia tyrosine kinase [EC:2.7.10.2] (A)	NF-kappa B signaling pathway (ko04064);; Osteoclast differentiation (ko04380);; Platelet activation (ko04611);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Primary immunodeficiency (ko05340)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; BTK motif;; PH domain;; Variant SH3 domain;; Variant SH3 domain;; Bacterial SH3 domain	Tyrosine-protein kinase BTK GN=BTK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase BTK isoform X2 [Equus caballus]
ENSG00000010704(HFE)	--	15.1419626	801	11.2297958	706	15.44707895	754	12.20528163	585	8.137390848	582	10.49073368	657	0.420234269	-0.4831085	normal	0.894750482	-0.29936806	normal	0.950341215	-0.206518481	normal	0.077720739	-0.330682311	normal	--	--	--	--	--	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain"	Hereditary hemochromatosis protein (Precursor) GN=HFE OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: hereditary hemochromatosis protein homolog isoform X2 [Camelus ferus]
ENSG00000010803(SCMH1)	--	6.646889762	441	5.181875807	338	5.906321547	387	6.972248659	477	7.163970403	486	6.323494874	437	0.967773827	0.082103277	normal	0.445403438	0.500629184	normal	0.955191797	0.166396033	normal	0.31996545	0.242487589	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K11461|0|hsa:22955|SCMH1, Scml3; sex comb on midleg homolog 1 (Drosophila); K11461 polycomb protein SCMH1 (A)"	--	[K]	Transcription	mbt repeat;; Protein of unknown function (DUF3588);; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Polycomb protein SCMH1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: polycomb protein SCMH1 isoform 1 [Ceratotherium simum simum]
ENSG00000010810(FYN)	--	5.85896696	341	4.743257006	183	4.209022747	262	2.202429524	87	1.801693804	90	1.376831174	61	1.11E-16	-1.982409337	down	0.002246065	-1.03284122	down	1.89E-15	-2.083825877	down	0.000262458	-1.745527026	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05703|0|ptr:462944|FYN; FYN proto-oncogene, Src family tyrosine kinase; K05703 tyrosine-protein kinase Fyn [EC:2.7.10.2] (A)"	Sphingolipid signaling pathway (ko04071);; Axon guidance (ko04360);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Platelet activation (ko04611);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; Cholinergic synapse (ko04725);; Prion diseases (ko05020);; Measles (ko05162);; Viral myocarditis (ko05416)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Tyrosine-protein kinase Fyn GN=FYN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase Fyn isoformX2 [Canis lupus familiaris] 
ENSG00000010818(HIVEP2)	--	2.114496647	446	2.549670784	534	2.501559202	517	2.6156932	549	2.726042753	574	4.188004079	884	0.91622174	0.268096563	normal	0.969041728	0.082558899	normal	0.002029882	0.763861876	normal	0.35056211	0.403264979	normal	[R]	General function prediction only	--	"K09239|0|hsa:3097|HIVEP2, HIV-EP2, MBP-2, MIBP1, SHN2, ZAS2, ZNF40B; human immunodeficiency virus type I enhancer binding protein 2; K09239 human immunodeficiency virus type I enhancer-binding protein (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger"	Transcription factor HIVEP2 GN=HIVEP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor HIVEP2 [Tupaia chinensis]
ENSG00000011007(ELOA)	--	8.564974	794	8.958947	843	9.967301788	913	11.86476	1106	10.37973	966	9.93954	953	0.555990732	0.446573122	normal	0.962746213	0.174770941	normal	0.977710799	0.053483197	normal	0.238989022	0.224945142	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Cellular Component: integral component of membrane (GO:0016021);; "	"K15076|0|hsa:6924|TCEB3, EloA, SIII, SIII_p110, TCEB3A; transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A); K15076 transcription elongation factor B, polypeptide 3 (A)"	--	[K]	Transcription	RNA polymerase II transcription factor SIII (Elongin) subunit A;; TFIIS helical bundle-like domain	Transcription elongation factor B polypeptide 3 GN=TCEB3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription elongation factor B polypeptide 3 [Odobenus rosmarus divergens]
ENSG00000011009(LYPLA2)	--	27.79974711	825	24.201685	743	26.79566798	783	34.569441	979	32.95631702	980	31.76316653	912	0.951184441	0.215713359	normal	0.783800991	0.377322378	normal	0.951786703	0.211351503	normal	0.150561179	0.266917911	normal	[R]	General function prediction only	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	K06130|3.08976e-169|umr:103666557|LYPLA2; lysophospholipase II; K06130 lysophospholipase II [EC:3.1.1.5] (A)	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Phospholipase/Carboxylesterase;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold	Acyl-protein thioesterase 2 GN=LYPLA2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: acyl-protein thioesterase 2 [Ochotona princeps]
ENSG00000011021(CLCN6)	--	4.531026	466	5.427197289	554	5.0939629	520	3.787665	379	4.4355089	449	7.422744	737	0.86407238	-0.327763534	normal	0.868288366	-0.323613798	normal	0.391211183	0.493649748	normal	1	0.004038144	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05015|0|ptr:457955|CLCN6; chloride channel, voltage-sensitive 6; K05015 chloride channel 6 (A)"	--	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	Chloride transport protein 6 GN=CLCN6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: chloride transport protein 6 [Tupaia chinensis]
ENSG00000011028(MRC2)	--	56.26161	6859	44.1741265	5479	43.98657715	5530	31.23718342	3826	40.315637	4892	29.71556934	3641	2.31E-05	-0.872727891	normal	0.986881506	-0.184860723	normal	0.058712518	-0.611028708	normal	0.009317791	-0.553141331	normal	--	--	--	"K06560|0|hsa:9902|MRC2, CD280, CLEC13E, ENDO180, UPARAP; mannose receptor, C type 2; K06560 mannose receptor, C type (A)"	Phagosome (ko04145);; Tuberculosis (ko05152)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; Fibronectin type II domain;; UL45 protein;; Chordopoxvirus A33R protein	C-type mannose receptor 2 (Precursor) GN=MRC2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C-type mannose receptor 2 [Ceratotherium simum simum]
ENSG00000011052(NME1-NME2)	--	1225.185842	14267	1227.648053	14995	1244.53239	15461	1408.96671	17327	1311.339567	15207	1298.373313	15637	0.990439502	0.249483211	normal	0.997227862	-0.001172393	normal	0.997394569	0.008037896	normal	0.748854981	0.085691571	normal	[F]	Nucleotide transport and metabolism	--	K00940|0|mcc:707717|hypothetical protein LOC707717; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Nucleoside diphosphate kinase;; Photosystem I reaction centre subunit IX / PsaJ	Nucleoside diphosphate kinase B GN=NME2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: nucleoside diphosphate kinase B-like isoform 1 [Dasypus novemcinctus]
ENSG00000011083(SLC6A7)	--	0	0	0	0	0	0	0.0278223	2	0.0678457	4	0.0137907	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05038|0|hsa:6534|SLC6A7, PROT; solute carrier family 6 (neurotransmitter transporter), member 7; K05038 solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium-dependent proline transporter GN=SLC6A7 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent proline transporter [Mustela putorius furo] 
ENSG00000011105(TSPAN9)	--	7.367362349	555	6.24931009	518	7.563084	492	9.548351296	724	10.09827075	795	8.527504347	619	0.824919446	0.35181484	normal	0.101407839	0.595163711	normal	0.868466908	0.322105139	normal	0.018385583	0.428412879	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17350|1.29035e-142|mcc:721790|TSPAN9; tetraspanin 9; K17350 tetraspanin-9 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-9 GN=TSPAN9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetraspanin-9 isoform X1 [Myotis lucifugus]
ENSG00000011114(BTBD7)	--	6.335668997	792	6.676051379	855	7.17139009	857	8.404006972	1054	8.991061198	1169	8.036325126	1010	0.768898241	0.380828012	normal	0.639425023	0.429200429	normal	0.947210066	0.228325216	normal	0.04002698	0.347448878	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10479|0|hsa:55727|BTBD7, FUP1; BTB (POZ) domain containing 7; K10479 BTB/POZ domain-containing protein 7 (A)"	--	[R]	General function prediction only	BTB/POZ domain;; BTB And C-terminal Kelch	BTB/POZ domain-containing protein 7 GN=BTBD7 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 7 isoform X1 [Vicugna pacos]
ENSG00000011132(APBA3)	--	4.939924	180	4.230727	159	5.25946	195	5.184065	191	4.94459	178	4.72738	172	0.9660756	0.054293561	normal	0.958782231	0.140163483	normal	0.952297812	-0.187805096	normal	1	-0.00244618	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Phosphotyrosine interaction domain (PTB/PID);; PDZ domain (Also known as DHR or GLGF)	Amyloid beta A4 precursor protein-binding family A member 3 GN=APBA3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: amyloid beta A4 precursor protein-binding family A member 3 [Canis lupus familiaris]
ENSG00000011143(MKS1)	--	6.150814399	204	6.083210738	192	8.835504052	229	7.679340829	288	8.630176362	271	9.096410637	267	0.669203536	0.463715438	normal	0.664938443	0.472612717	normal	0.943648654	0.211903558	normal	0.167109206	0.381134614	normal	--	--	--	--	--	[S]	Function unknown	"Ciliary basal body-associated, B9 protein"	Meckel syndrome type 1 protein GN=MKS1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Meckel syndrome type 1 protein [Ceratotherium simum simum]
ENSG00000011198(ABHD5)	--	4.412874	204	5.68777	278	5.634517	265	7.92717	373	6.98189	310	7.846654	344	0.003439574	0.835057987	normal	0.958072193	0.135060777	normal	0.829883619	0.366285195	normal	0.06782765	0.437852195	normal	[R]	General function prediction only	--	"K13699|0|hsa:51099|ABHD5, CDS, CGI58, IECN2, NCIE2; abhydrolase domain containing 5 (EC:2.3.1.51); K13699 abhydrolase domain-containing protein 5 [EC:2.3.1.51] (A)"	--	[R]	General function prediction only	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	1-acylglycerol-3-phosphate O-acyltransferase ABHD5 GN=ABHD5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 [Oryctolagus cuniculus]
ENSG00000011201(ANOS1)	--	0.0191205	2	0.00965245	1	0.0479387	4	0.00951122	1	0.0369067	3	0.0378229	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Molecular Function: peptidase inhibitor activity (GO:0030414);; 	--	--	[W]	Extracellular structures	Fibronectin type III domain;; WAP-type (Whey Acidic Protein) 'four-disulfide core'	Anosmin-1 (Precursor) GN=KAL1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	"PREDICTED: anosmin-1-like, partial [Ceratotherium simum simum]"
ENSG00000011243(AKAP8L)	--	14.15002058	665	15.56786278	661	14.56872274	690	12.62290451	584	14.4776949	606	17.81437719	821	0.944273656	-0.217681058	normal	0.962947026	-0.146409058	normal	0.936862916	0.242007591	normal	0.955958996	-0.023685673	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	K15978|0|pon:100457553|AKAP8L; A kinase (PRKA) anchor protein 8-like; K15978 A-kinase anchor protein 8-like protein (A)	Epstein-Barr virus infection (ko05169)	--	--	A-kinase anchoring protein 95 (AKAP95)	A-kinase anchor protein 8-like GN=AKAP8L OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 8-like isoform X3 [Oryctolagus cuniculus]
ENSG00000011258(MBTD1)	--	5.576986	423	5.68201	445	6.040985	405	5.99217	461	5.561776707	450	6.519351	499	0.96648791	0.092953363	normal	0.969922643	-0.005289019	normal	0.899159836	0.291843033	normal	0.660929593	0.126360251	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	mbt repeat	MBT domain-containing protein 1 GN=MBTD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: MBT domain-containing protein 1 isoform X4 [Tupaia chinensis]
ENSG00000011260(UTP18)	--	42.912096	1540	48.08549503	1762	50.431767	1784	44.28972095	1617	47.028733	1679	43.00098864	1544	0.984100241	0.039518587	normal	0.98257497	-0.090958267	normal	0.963661535	-0.216536812	normal	0.685025699	-0.092703941	normal	[R]	General function prediction only	--	"K14553|0|hsa:51096|UTP18, CGI-48, WDR50; UTP18 small subunit (SSU) processome component homolog (yeast); K14553 U3 small nucleolar RNA-associated protein 18 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	"WD domain, G-beta repeat;; Anaphase-promoting complex subunit 4 WD40 domain"	U3 small nucleolar RNA-associated protein 18 homolog GN=UTP18 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: U3 small nucleolar RNA-associated protein 18 homolog [Ceratotherium simum simum]
ENSG00000011275(RNF216)	--	15.27677	1748	14.029548	1690	16.120365	1816	13.7227	1616	13.93097	1618	15.46524	1823	0.977984264	-0.14397858	normal	0.982512988	-0.084161219	normal	0.986001589	-0.002738807	normal	0.748239693	-0.075867707	normal	--	--	--	"K11976|0|hsa:54476|RNF216, CAHH, TRIAD3, U7I1, UBCE7IP1, ZIN; ring finger protein 216; K11976 TRIAD3; E3 ubiquitin-protein ligase RNF216 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	E3 ubiquitin-protein ligase RNF216 GN=RNF216 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF216 isoform X1 [Galeopterus variegatus] 
ENSG00000011295(TTC19)	--	28.255364	1249	25.222775	1188	26.53497	1137	28.738408	1313	32.15841	1456	28.048364	1275	0.981779811	0.041211731	normal	0.933953122	0.271736049	normal	0.971278931	0.156776539	normal	0.436464399	0.156920794	normal	[R]	General function prediction only	Molecular Function: identical protein binding (GO:0042802);; 	"K18169|0|ggo:101147464|TTC19; tetratricopeptide repeat protein 19, mitochondrial isoform 1; K18169 tetratricopeptide repeat protein 19, mitochondrial (A)"	--	[Z]	Cytoskeleton	Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex subunit 5	"Tetratricopeptide repeat protein 19, mitochondrial (Precursor) GN=TTC19 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: tetratricopeptide repeat domain 19 [Tupaia chinensis]
ENSG00000011304(PTBP1)	--	127.341441	6359	122.9764389	6186	116.054959	6270	141.1617848	7409	139.5848562	7187	130.1582281	6927	0.989223568	0.189604191	normal	0.988339677	0.194912055	normal	0.992247759	0.135442697	normal	0.39790268	0.172612422	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K13218|0|hgl:101715554|Ptbp1; polypyrimidine tract binding protein 1; K13218 polypyrimidine tract-binding protein 1 (A)	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Polypyrimidine tract-binding protein 1 GN=PTBP1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: polypyrimidine tract-binding protein 1 isoform 3 [Tursiops truncatus]
ENSG00000011332(DPF1)	--	2.94801158	136	1.811307909	88	3.095379476	144	2.7999404	132	2.071247005	98	1.897941577	89	0.967029864	-0.073063089	normal	0.966349842	0.131706182	normal	0.356586853	-0.693134504	normal	0.646315902	-0.228079531	normal	--	--	--	--	--	[K]	Transcription	N-terminal domain of DPF2/REQ.;; PHD-finger	Zinc finger protein neuro-d4 GN=DPF1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein neuro-d4 [Oryctolagus cuniculus]
ENSG00000011347(SYT7)	--	0.43767143	48	0.176556446	17	1.093493061	31	0.28126831	23	0.48138292	50	0.214938741	22	0.551511335	-1.042952101	normal	0.06436665	1.45619665	normal	0.973347445	-0.475402112	normal	0.989936683	-0.035836334	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-7 GN=SYT7 OS=Homo sapiens (Human) PE=1 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mucin-19 isoform 2 [Canis lupus familiaris]
ENSG00000011376(LARS2)	--	6.258706487	586	6.587173913	624	6.580472685	594	8.21277779	731	6.630766556	613	7.501009	701	0.904314425	0.28746256	normal	0.972442308	-0.046970659	normal	0.939920019	0.230120193	normal	0.502782233	0.159461246	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA editing activity (GO:0002161);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01869|0|hsa:23395|LARS2, LEURS, PRLTS4; leucyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.4); K01869 leucyl-tRNA synthetase [EC:6.1.1.4] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (I, L, M and V);; tRNA synthetases class I (M);; Anticodon-binding domain of tRNA;; Leucyl-tRNA synthetase, Domain 2"	"Probable leucine--tRNA ligase, mitochondrial (Precursor) GN=LARS2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable leucine--tRNA ligase, mitochondrial [Ceratotherium simum simum]"
ENSG00000011405(PIK3C2A)	--	14.73070409	2117	15.69397455	2290	15.089125	2181	14.04890785	2115	12.2939313	1847	16.47106799	2455	0.987130923	-0.032172509	normal	0.900136794	-0.331346111	normal	0.98010477	0.162335662	normal	0.816543769	-0.058777291	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K00923|0|hsa:5286|PIK3C2A, CPK, PI3-K-C2(ALPHA), PI3-K-C2A; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (EC:2.7.1.154); K00923 phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	"Phosphatidylinositol 3- and 4-kinase;; Phosphoinositide 3-kinase family, accessory domain (PIK domain);; Phosphoinositide 3-kinase C2;; PI3-kinase family, ras-binding domain;; PX domain;; C2 domain"	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha GN=PIK3C2A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000011422(PLAUR)	--	34.3246043	944	27.9308622	801	29.6527501	843	48.31447559	1351	43.07907031	1181	33.72424271	966	0.391562123	0.48567278	normal	0.217940444	0.537867117	normal	0.960003064	0.187884031	normal	0.053643484	0.412482054	normal	--	--	--	"K03985|0|pps:100980178|PLAUR; plasminogen activator, urokinase receptor; K03985 plasminogen activator, urokinase receptor (A)"	Complement and coagulation cascades (ko04610);; Proteoglycans in cancer (ko05205)	--	--	u-PAR/Ly-6 domain	Urokinase plasminogen activator surface receptor (Precursor) GN=PLAUR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: urokinase plasminogen activator surface receptor [Galeopterus variegatus]
ENSG00000011426(ANLN)	--	42.68016853	3570	40.69613894	3385	45.48991846	3784	62.67589438	5373	49.94329685	4195	43.20332885	3712	0.178234285	0.558774255	normal	0.95718943	0.287972661	normal	0.991524597	-0.035992297	normal	0.270087574	0.284188937	normal	--	--	--	"K18621|0|pps:100992973|ANLN; anillin, actin binding protein; K18621 actin-binding protein anillin (A)"	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Cell division protein anillin;; PH domain	Actin-binding protein anillin GN=ANLN OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: actin-binding protein anillin isoform 1 [Ceratotherium simum simum]
ENSG00000011451(WIZ)	--	11.1317227	910	12.19425372	987	11.75063199	959	12.41758871	1019	12.83157355	1048	14.24487033	1158	0.971488712	0.132172384	normal	0.977694107	0.064993522	normal	0.932324566	0.263362625	normal	0.467167642	0.154497662	normal	--	--	--	--	--	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc finger, C2H2 type;; MYM-type Zinc finger with FCS sequence motif;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies)"	Protein Wiz GN=WIZ OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein Wiz isoform 1 [Odobenus rosmarus divergens]
ENSG00000011454(RABGAP1)	--	0	0	0.222111	3	0	0	0.0723079	1	0.143739	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; Kinesin protein;; Phosphotyrosine interaction domain (PTB/PID)	Rab GTPase-activating protein 1 GN=RABGAP1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: rab GTPase-activating protein 1 [Echinops telfairi]
ENSG00000011454(RABGAP1)-2	--	13.285318	1251	16.11891	1447	14.34445	1306	12.18579	1204	12.941305	1241	12.81634	1261	0.97922497	-0.08597102	normal	0.949494543	-0.242714137	normal	0.981250182	-0.058808757	normal	0.532564388	-0.132707735	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000011465(DCN)	--	0.033185716	1	0	0	0	0	0	0	0.178758444	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K04660|0|ptr:452120|DCN; decorin; K04660 decorin (A)	TGF-beta signaling pathway (ko04350);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain;; Leucine rich repeats (6 copies);; Leucine-rich repeat	Decorin (Precursor) GN=DCN OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: decorin [Felis catus] 
ENSG00000011478(QPCTL)	--	11.889604	458	10.986645	427	10.36707503	412	10.112906	393	9.065514	349	9.601257	374	0.925899141	-0.250741378	normal	0.883845217	-0.31121408	normal	0.95856071	-0.147329668	normal	0.344700188	-0.238339453	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M28	Glutaminyl-peptide cyclotransferase-like protein GN=QPCTL OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutaminyl-peptide cyclotransferase-like protein [Galeopterus variegatus] 
ENSG00000011485(PPP5C)	--	40.66661282	1778	39.56981559	1744	37.522854	1664	36.725626	1613	38.021787	1656	34.35711054	1510	0.974193639	-0.171185753	normal	0.982123316	-0.096038449	normal	0.976664348	-0.14825682	normal	0.498235587	-0.139362345	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; Molecular Function: hydrolase activity (GO:0016787);; 	"K04460|0|ptr:456150|PPP5C; protein phosphatase 5, catalytic subunit; K04460 serine/threonine-protein phosphatase 5 [EC:3.1.3.16] (A)"	MAPK signaling pathway (ko04010)	[R]	General function prediction only	Calcineurin-like phosphoesterase;; PPP5 TPR repeat region;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Serine/threonine-protein phosphatase 5 GN=PPP5C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 5 [Tupaia chinensis]
ENSG00000011523(CEP68)	--	6.197369806	672	6.212285611	692	7.001688188	773	4.49098158	502	4.518365388	497	4.483131643	478	0.561714163	-0.450409844	normal	0.398410717	-0.497663074	normal	0.011014629	-0.699990614	normal	0.001387667	-0.554020785	normal	--	--	--	"K16764|0|hsa:23177|CEP68, KIAA0582; centrosomal protein 68kDa; K16764 centrosomal protein CEP68 (A)"	--	--	--	--	Centrosomal protein of 68 kDa GN=CEP68 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 68 kDa [Ceratotherium simum simum]
ENSG00000011566(MAP4K3)	--	18.52768023	1408	19.59696478	1481	19.17058084	1413	15.70639082	1117	14.40821372	954	16.76839027	1273	0.817093994	-0.364402791	normal	0.021205711	-0.655096404	normal	0.972656913	-0.158641517	normal	0.014702885	-0.384347256	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04406|0|mcf:102130367|MAP4K3; mitogen-activated protein kinase kinase kinase kinase 3; K04406 mitogen-activated protein kinase kinase kinase kinase 3 [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	CNH domain;; Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase kinase 3 GN=MAP4K3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase kinase 3 isoformX2 [Canis lupus familiaris]
ENSG00000011590(ZBTB32)	--	0.155055181	6	0.153556061	6	0.124919203	4	0.051543989	2	0.050200623	1	0.152794969	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10506|0|hsa:27033|ZBTB32, FAXF, FAZF, Rog, TZFP, ZNF538; zinc finger and BTB domain containing 32; K10506 zinc finger and BTB domain-containing protein 32 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; C2H2-type zinc finger;; BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 32 GN=ZBTB32 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 32 isoform X1 [Galeopterus variegatus]
ENSG00000011638(TMEM159)	--	15.43524867	320	13.474582	279	14.31700271	310	18.91911177	373	15.58652603	335	17.614931	363	0.948688669	0.189428457	normal	0.930704164	0.241274558	normal	0.940057951	0.21842426	normal	0.447868527	0.21538053	normal	--	--	--	--	--	--	--	--	Promethin GN=TMEM159 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: promethin isoform 1 [Odobenus rosmarus divergens]
ENSG00000011677(GABRA3)	--	2.121534578	148	1.603641174	114	2.115761955	132	0.18959292	13	0.380573623	17	0.053032482	4	0	-3.391793005	down	3.02E-12	-2.661902467	down	0	-4.605284863	down	4.49E-19	-3.557760219	down	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05175|0|pps:100971836|GABRA3; gamma-aminobutyric acid (GABA) A receptor, alpha 3; K05175 gamma-aminobutyric acid receptor subunit alpha (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Gamma-aminobutyric acid receptor subunit alpha-3 (Precursor) GN=GABRA3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit alpha-3 [Oryctolagus cuniculus]
ENSG00000012048(BRCA1)	--	18.98616903	2036	19.41448902	2178	27.58978059	2560	21.58795802	2223	18.73725826	1823	18.20314353	1895	0.984944302	0.095868876	normal	0.943030014	-0.277904714	normal	0.622551209	-0.441932782	normal	0.277314787	-0.210706399	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10605|0|hsa:672|BRCA1, BRCAI, BRCC1, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, PSCP, RNF53; breast cancer 1, early onset; K10605 breast cancer type 1 susceptibility protein (A)"	Fanconi anemia pathway (ko03460);; Ubiquitin mediated proteolysis (ko04120);; PI3K-Akt signaling pathway (ko04151);; MicroRNAs in cancer (ko05206)	[LK]	"Replication, recombination and repair;; Transcription"	"Ethylene insensitive 3;; Serine-rich domain associated with BRCT;; BRCA1 C Terminus (BRCT) domain;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc-finger of the MIZ type in Nse subunit"	Breast cancer type 1 susceptibility protein GN=BRCA1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: breast cancer type 1 susceptibility protein homolog isoform 1 [Ceratotherium simum simum]
ENSG00000012061(ERCC1)	--	73.3477117	2559	56.9656454	2223	59.908316	2488	52.236053	1954	57.11963404	2160	47.82512792	1855	0.707243847	-0.419692565	normal	0.986377283	-0.062859809	normal	0.661367225	-0.431553819	normal	0.058695877	-0.305638066	normal	[L]	"Replication, recombination and repair"	Molecular Function: damaged DNA binding (GO:0003684);; Molecular Function: endonuclease activity (GO:0004519);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA repair (GO:0006281);; 	"K10849|0|mcf:102117117|ERCC1; excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence); K10849 DNA excision repair protein ERCC-1 (A)"	Nucleotide excision repair (ko03420);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	Binding domain of DNA repair protein Ercc1 (rad10/Swi10)	DNA excision repair protein ERCC-1 GN=ERCC1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA excision repair protein ERCC-1 [Galeopterus variegatus]
ENSG00000012124(CD22)	--	0.771541783	31	0.601097192	28	1.0983881	55	0.64224742	45	0.300354051	20	0.345607493	14	0.957223065	0.486708685	normal	0.97503007	-0.476279324	normal	0.001261889	-1.872929456	down	0.589517697	-0.552857342	normal	--	--	--	"K06467|0|pps:100980861|CD22, SIGLEC2, siglec-2; CD22 molecule; K06467 CD22 antigen (A)"	Cell adhesion molecules (CAMs) (ko04514);; Hematopoietic cell lineage (ko04640);; B cell receptor signaling pathway (ko04662)	[RP]	General function prediction only;; Inorganic ion transport and metabolism	"Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin C1-set domain;; Intercellular adhesion molecule (ICAM), N-terminal domain"	B-cell receptor CD22 (Precursor) GN=CD22 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: B-cell receptor CD22 [Tupaia chinensis]
ENSG00000012171(SEMA3B)	--	6.788890282	373	4.114758573	268	5.9226797	313	11.84452393	608	15.18802126	798	12.2854497	686	0.028751444	0.671876158	normal	2.24E-14	1.547422968	up	1.64E-07	1.120006725	up	6.15E-08	1.112113682	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06840|0|hsa:7869|SEMA3B, LUCA-1, SEMA5, SEMAA, SemA, semaV; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B; K06840 semaphorin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat;; Immunoglobulin V-set domain	Semaphorin-3B (Precursor) GN=SEMA3B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-3B isoform X3 [Galeopterus variegatus]
ENSG00000012174(MBTPS2)	--	27.407652	1738	27.488202	1733	28.629338	1777	22.748711	1452	20.908034	1323	24.972259	1585	0.926083156	-0.289938007	normal	0.720876229	-0.410473818	normal	0.973777465	-0.173096212	normal	0.081335191	-0.28836844	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K07765|0|aml:100465637|membrane-bound transcription factor site-2 protease-like; K07765 S2P endopeptidase [EC:3.4.24.85] (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M50	Membrane-bound transcription factor site-2 protease GN=MBTPS2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: membrane-bound transcription factor site-2 protease [Ailuropoda melanoleuca]
ENSG00000012211(PRICKLE3)	--	10.76308758	395	10.01327137	356	9.984754666	377	11.0412823	404	10.30306192	361	8.707748048	322	0.969681582	0.001663976	normal	0.968016755	-0.00129948	normal	0.93376699	-0.234775124	normal	0.833277129	-0.0752652	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	PET Domain;; LIM domain	Prickle-like protein 3 GN=PRICKLE3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: prickle-like protein 3 isoform 1 [Orcinus orca]
ENSG00000012232(EXTL3)	--	12.48672212	1369	10.88770076	1189	10.96208904	1145	13.39303631	1423	15.45039196	1653	11.25411344	1149	0.983085262	0.024953483	normal	0.56007266	0.453420337	normal	0.981173114	-0.00325595	normal	0.575135028	0.168443708	normal	--	--	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K02370|0|hsa:2137|EXTL3, BOTV, EXTL1L, EXTR1, REGR, RPR; exostosin-like glycosyltransferase 3 (EC:2.4.1.223); K02370 alpha-1,4-N-acetylglucosaminyltransferase EXTL3 [EC:2.4.1.223 2.4.1.224] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[T]	Signal transduction mechanisms	Glycosyl transferase family 64 domain;; Exostosin family	Exostosin-like 3 GN=EXTL3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: exostoses (multiple)-like 3 [Equus caballus]
ENSG00000012504(NR1H4)	--	0.126167384	5	0.224705196	6	0.168291218	4	0.839293413	27	0.696387815	33	2.080690813	63	0.101683993	2.099847257	normal	0.016032041	2.180986571	normal	4.30E-10	3.541794226	up	0.001907741	3.016395601	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08537|0|mcf:102143900|NR1H4; nuclear receptor subfamily 1, group H, member 4; K08537 farnesoid X receptor (A)"	Bile secretion (ko04976)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Bile acid receptor GN=NR1H4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: bile acid receptor isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000012660(ELOVL5)	--	77.803127	2988	79.10089344	3100	78.32761089	2994	78.07871	3020	76.847441	2889	85.965005	3277	0.990200512	-0.015455957	normal	0.986459104	-0.123062364	normal	0.987218855	0.121951114	normal	0.989389689	-0.004580883	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K10244|0|hsa:60481|ELOVL5, HELO1, SCA38, dJ483K16.1; ELOVL fatty acid elongase 5 (EC:2.3.1.199); K10244 elongation of very long chain fatty acids protein 5 [EC:2.3.1.199] (A)"	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	GNS1/SUR4 family	Elongation of very long chain fatty acids protein 5 GN=ELOVL5 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: elongation of very long chain fatty acids protein 5 isoform X1 [Echinops telfairi]
ENSG00000012779(ALOX5)	--	0.573228435	28	0.375487721	18	0.537381041	25	1.328285564	64	2.1512272	104	1.149522839	56	0.191570338	1.120131526	normal	8.93E-10	2.414513567	up	0.307942522	1.109263097	normal	0.00367814	1.636629082	up	--	--	"Molecular Function: protein binding (GO:0005515);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00461|0|hsa:240|ALOX5, 5-LO, 5-LOX, 5LPG, LOG5; arachidonate 5-lipoxygenase (EC:1.13.11.34); K00461 arachidonate 5-lipoxygenase [EC:1.13.11.34] (A)"	Arachidonic acid metabolism (ko00590);; Serotonergic synapse (ko04726);; Ovarian steroidogenesis (ko04913);; Toxoplasmosis (ko05145)	--	--	Lipoxygenase;; PLAT/LH2 domain	Arachidonate 5-lipoxygenase GN=ALOX5 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: arachidonate 5-lipoxygenase isoform X1 [Mustela putorius furo] 
ENSG00000012817(KDM5D)	--	7.548925115	848	7.7794108	875	7.24137434	837	2.637189254	300	3.03738112	315	3.991385079	406	9.99E-15	-1.525069184	down	7.88E-14	-1.490869687	down	6.38E-07	-1.049256943	down	1.52E-17	-1.346507711	down	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K11446|0|hsa:8284|KDM5D, HY, HYA, JARID1D, SMCY; lysine (K)-specific demethylase 5D; K11446 histone demethylase JARID1 [EC:1.14.11.-] (A)"	--	[R]	General function prediction only	"PLU-1-like protein;; JmjC domain, hydroxylase;; ARID/BRIGHT DNA binding domain;; C5HC2 zinc finger;; PHD-finger;; jmjN domain"	Lysine-specific demethylase 5D GN=KDM5D OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lysine-specific demethylase 5D isoform X1 [Galeopterus variegatus]
ENSG00000012822(CALCOCO1)	--	14.04277385	694	13.33768861	727	12.86081386	723	15.20219696	676	17.87703485	828	16.58660884	920	0.973113583	-0.068590809	normal	0.962198572	0.165925258	normal	0.849493187	0.33871726	normal	0.508085651	0.156862715	normal	--	--	--	--	--	--	--	Calcium binding and coiled-coil domain (CALCOCO1) like	Calcium-binding and coiled-coil domain-containing protein 1 GN=CALCOCO1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: calcium-binding and coiled-coil domain-containing protein 1 isoform 1 [Equus caballus]
ENSG00000012963(UBR7)	--	30.86197989	968	28.25027152	875	31.5775915	1019	34.910757	1268	30.435479	1051	39.199767	1115	0.824493277	0.358145587	normal	0.941585551	0.242598173	normal	0.974339926	0.121425892	normal	0.186071728	0.241415596	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	K11979|0|ptr:453125|UBR7; ubiquitin protein ligase E3 component n-recognin 7 (putative); K11979 E3 ubiquitin-protein ligase UBR7 [EC:6.3.2.19] (A)	--	[R]	General function prediction only	Putative zinc finger in N-recognin (UBR box)	Putative E3 ubiquitin-protein ligase UBR7 GN=UBR7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: putative E3 ubiquitin-protein ligase UBR7 [Equus caballus]
ENSG00000012983(MAP4K5)	--	18.9366666	1150	14.17576243	984	18.61414455	1164	21.84392469	1336	22.08648038	1328	15.66844821	1096	0.966111234	0.185224138	normal	0.705405309	0.410553413	normal	0.977598509	-0.095007473	normal	0.401096861	0.16760558	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08833|0|hsa:11183|MAP4K5, GCKR, KHS, KHS1, MAPKKKK5; mitogen-activated protein kinase kinase kinase kinase 5 (EC:2.7.11.1); K08833 mitogen-activated protein kinase kinase kinase kinase 5 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	CNH domain;; Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase kinase 5 GN=MAP4K5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase kinase 5 [Vicugna pacos]
ENSG00000013016(EHD3)	--	9.5081	1006	8.57811	928	9.59274	1021	4.220967	444	5.760809	588	4.799028	515	1.07E-09	-1.207972202	down	0.016954726	-0.678333696	normal	2.02E-06	-0.993516776	normal	2.72E-10	-0.95422944	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; 	"K12476|0|hsa:30845|EHD3, PAST3; EH-domain containing 3; K12476 EH domain-containing protein 3 (A)"	Endocytosis (ko04144)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Dynamin family;; Cytoskeletal-regulatory complex EF hand;; 50S ribosome-binding GTPase	EH domain-containing protein 3 GN=EHD3 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: EH domain-containing protein 3 [Oryctolagus cuniculus]
ENSG00000013275(PSMC4)	--	122.6791	3810	121.5341	3788	126.34029	3983	124.26026	3906	124.96689	3859	107.89418	3387	0.991944456	0.00506667	normal	0.991622428	0.005362034	normal	0.972543342	-0.242039162	normal	0.753772008	-0.075953642	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	"K03063|0|tup:102476929|PSMC4; proteasome (prosome, macropain) 26S subunit, ATPase, 4; K03063 26S proteasome regulatory subunit T3 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily);; AAA domain (Cdc48 subfamily);; Holliday junction DNA helicase ruvB N-terminus;; Protein of unknown function (DUF815)	26S protease regulatory subunit 6B GN=PSMC4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S protease regulatory subunit 6B isoform X1 [Myotis lucifugus] 
ENSG00000013288(MAN2B2)	--	9.890843535	1122	10.45290316	1158	8.855334665	1010	9.295461826	1060	10.31193442	1098	8.951901341	1003	0.975500717	-0.112681887	normal	0.976860865	-0.098052232	normal	0.979569556	-0.018297636	normal	0.75045786	-0.079244022	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: alpha-mannosidase activity (GO:0004559);; Biological Process: mannose metabolic process (GO:0006013);; 	"K12312|0|pps:100982980|MAN2B2; mannosidase, alpha, class 2B, member 2; K12312 epididymis-specific alpha-mannosidase [EC:3.2.1.24] (A)"	Other glycan degradation (ko00511)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolases family 38 C-terminal domain;; Glycosyl hydrolases family 38 N-terminal domain;; Alpha mannosidase, middle domain"	Epididymis-specific alpha-mannosidase (Precursor) GN=MAN2B2 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: epididymis-specific alpha-mannosidase [Galeopterus variegatus]
ENSG00000013297(CLDN11)	--	0.0469652	2	0.20628754	9	0.067741971	2	0.30170072	13	0.473530075	15	0.371930075	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|4.38126e-105|pon:100436219|CLDN11; claudin 11; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family	Claudin-11 GN=CLDN11 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: claudin-11 [Ceratotherium simum simum]
ENSG00000013306(SLC25A39)	--	100.214647	2402	83.75179959	2145	90.00978701	2305	95.46653847	2315	97.20548325	2379	88.91058355	2213	0.986581571	-0.084001483	normal	0.98309074	0.12786544	normal	0.986851135	-0.067009869	normal	0.978450565	-0.009712711	normal	--	--	--	"K15119|0|hsa:51629|SLC25A39, CGI69; solute carrier family 25, member 39; K15119 solute carrier family 25, member 39/40 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 39 GN=SLC25A39 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 39 isoform X1 [Galeopterus variegatus]
ENSG00000013364(MVP)	--	80.790598	4406	69.88661161	4297	75.51658439	4680	81.20149715	4667	81.2403369	4709	93.25263357	5149	0.992496585	0.05217603	normal	0.990568488	0.110627188	normal	0.990543923	0.129452405	normal	0.675329831	0.097372661	normal	--	--	--	K17266|0|ptr:454027|MVP; major vault protein; K17266 major vault protein (A)	--	--	--	Major Vault Protein repeat;; Shoulder domain	Major vault protein GN=MVP OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: major vault protein [Tupaia chinensis] 
ENSG00000013374(NUB1)	--	20.993927	1131	24.98043	1089	25.394099	1152	24.746968	1304	24.42557607	1364	23.87188311	1413	0.968111399	0.174292042	normal	0.907645884	0.303036433	normal	0.922125695	0.285989762	normal	0.149063632	0.254455144	normal	--	--	--	--	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	UBA/TS-N domain	NEDD8 ultimate buster 1 GN=NUB1 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: NEDD8 ultimate buster 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000013375(PGM3)	--	12.90873308	806	9.772683138	719	11.84156929	799	12.436515	896	13.74077023	960	13.8360348	932	0.971072789	0.121666601	normal	0.741028186	0.394895037	normal	0.951430441	0.21346857	normal	0.208393275	0.241686812	normal	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: intramolecular transferase activity, phosphotransferases (GO:0016868);; Biological Process: organic substance metabolic process (GO:0071704);; "	"K01836|0|hsa:5238|PGM3, AGM1, IMD23, PAGM, PGM_3; phosphoglucomutase 3 (EC:5.4.2.3); K01836 phosphoacetylglucosamine mutase [EC:5.4.2.3] (A)"	Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	"Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II;; Phosphoglucomutase/phosphomannomutase, C-terminal domain"	Phosphoacetylglucosamine mutase {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: phosphoacetylglucosamine mutase [Galeopterus variegatus]
ENSG00000013392(RWDD2A)	--	2.045377001	131	1.91440873	119	1.697347	100	2.173656	137	2.489023	152	1.965169	124	0.968270996	0.033393833	normal	0.916125812	0.327987297	normal	0.938538237	0.297994509	normal	0.635174568	0.217029612	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Protein of unknown function (DUF1115);; RWD domain	RWD domain-containing protein 2A GN=RWDD2A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RWD domain-containing protein 2A isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000013441(CLK1)	--	14.6413955	622	14.94664097	593	13.612913	519	9.194388059	385	16.07455265	676	15.0654443	566	0.009569394	-0.720602392	normal	0.958936154	0.167165089	normal	0.966151678	0.116451058	normal	0.815138112	-0.112134419	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08823|0|hsa:1195|CLK1, CLK, CLK/STY, STY; CDC-like kinase 1 (EC:2.7.12.1); K08823 CDC-like kinase [EC:2.7.12.1] (A)"	Legionellosis (ko05134)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Dual specificity protein kinase CLK1 GN=CLK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity protein kinase CLK1 [Ochotona princeps]
ENSG00000013503(POLR3B)	--	2.592626777	249	2.384375	230	2.644074401	240	3.425609483	318	4.246126207	389	3.451542695	308	0.884534931	0.320296363	normal	0.024207664	0.732964081	normal	0.857679093	0.349654866	normal	0.044686608	0.476273343	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K03021|0|umr:103676466|POLR3B; polymerase (RNA) III (DNA directed) polypeptide B; K03021 DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	"RNA polymerase Rpb2, domain 6;; RNA polymerase beta subunit;; RNA polymerase Rpb2, domain 7;; RNA polymerase Rpb2, domain 2;; RNA polymerase Rpb2, domain 3;; RNA polymerase Rpb2, domain 4;; RNA polymerase Rpb2, domain 5"	DNA-directed RNA polymerase III subunit RPC2 GN=POLR3B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC2 isoform X1 [Physeter catodon] 
ENSG00000013523(ANGEL1)	--	9.27806425	624	8.755706	660	7.7681445	598	7.440101021	558	7.510289	592	8.23586493	547	0.952264609	-0.191613897	normal	0.95630612	-0.177864825	normal	0.963967737	-0.136534938	normal	0.476554798	-0.170626854	normal	--	--	--	"K18729|0|hsa:23357|ANGEL1, Ccr4e, KIAA0759; angel homolog 1 (Drosophila); K18729 protein angel (A)"	--	[K]	Transcription	Endonuclease/Exonuclease/phosphatase family	Protein angel homolog 1 GN=ANGEL1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein angel homolog 1 [Odobenus rosmarus divergens]
ENSG00000013561(RNF14)	--	29.28802678	925	29.43267487	981	30.44757499	960	31.99149658	1084	33.09474015	1040	40.63612658	1259	0.959014178	0.197703644	normal	0.977721064	0.062737992	normal	0.771749946	0.382353034	normal	0.247094198	0.218496891	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11971|0|hsa:9604|RNF14, ARA54, HFB30, TRIAD2; ring finger protein 14; K11971 E3 ubiquitin-protein ligase RNF14 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	RWD domain;; IBR domain	E3 ubiquitin-protein ligase RNF14 GN=RNF14 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF14 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000013563(DNASE1L1)	--	24.5346626	862	22.63292553	821	26.14104046	857	27.33569035	915	22.88990561	807	26.57875101	949	0.976962768	0.055156186	normal	0.975780153	-0.046154354	normal	0.969759919	0.13858895	normal	0.857893181	0.051456645	normal	--	--	--	K11995|0|pps:100981231|DNASE1L1; deoxyribonuclease I-like 1; K11995 deoxyribonuclease-1-like protein [EC:3.1.21.-] (A)	--	--	--	Endonuclease/Exonuclease/phosphatase family	Deoxyribonuclease-1-like 1 (Precursor) GN=DNASE1L1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: deoxyribonuclease-1-like 1 [Ursus maritimus] 
ENSG00000013573(DDX11)	--	20.03412817	1567	18.02249528	1492	23.6820641	1667	17.23317137	1327	17.85408137	1317	18.85491231	1393	0.936464985	-0.270380574	normal	0.964428818	-0.201201513	normal	0.940282503	-0.267084853	normal	0.153254483	-0.248220454	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Molecular Function: ATP binding (GO:0005524);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: ATP-dependent helicase activity (GO:0008026);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; "	"K11273|0|hsa:1663|DDX11, CHL1, CHLR1, KRG2, WABS; DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 (EC:3.6.4.13); K11273 chromosome transmission fidelity protein 1 [EC:3.6.4.13] (A)"	--	[L]	"Replication, recombination and repair"	DEAD_2;; Helicase C-terminal domain;; Helicase C-terminal domain	Probable ATP-dependent RNA helicase DDX11 GN=DDX11 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: probable ATP-dependent RNA helicase DDX11-like isoform X2 [Bubalus bubalis]
ENSG00000013583(HEBP1)	--	37.070963	716	31.741202	620	34.74135036	676	46.82229698	905	47.807428	922	44.277603	859	0.889866187	0.30653977	normal	0.194011036	0.549965293	normal	0.851322367	0.336673778	normal	0.021758186	0.395561066	normal	--	--	--	--	--	--	--	SOUL heme-binding protein	Heme-binding protein 1 GN=HEBP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: heme-binding protein 1 [Oryctolagus cuniculus]
ENSG00000013588(GPRC5A)	--	128.2001828	7184	108.2236524	6376	166.7270168	9401	125.763846	7539	82.23717264	4744	111.0648267	6876	0.99504646	0.038745469	normal	0.732121496	-0.447850539	normal	0.722238176	-0.459449338	normal	0.497437647	-0.282221919	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08468|0|hsa:9052|GPRC5A, GPCR5A, PEIG-1, RAI3, RAIG1, TIG1; G protein-coupled receptor, class C, group 5, member A; K08468 G protein-coupled receptor family C group 5 member A (A)"	--	--	--	7 transmembrane sweet-taste receptor of 3 GCPR	Retinoic acid-induced protein 3 GN=GPRC5A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: retinoic acid-induced protein 3 [Felis catus]
ENSG00000013619(MAMLD1)	--	1.504646331	137	1.542924027	125	1.364127049	118	5.025441944	431	4.171036207	335	3.4110119	276	8.99E-13	1.611949369	up	1.51E-08	1.390131305	up	5.03E-06	1.207176299	up	4.36E-06	1.432544878	up	--	--	--	--	--	--	--	--	Mastermind-like domain-containing protein 1 GN=MAMLD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mastermind-like domain-containing protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000013725(CD6)	--	0.16734089	2	0	0	0.317212468	5	0.03561936	1	0	0	0.134432141	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	K06456|0|ptr:451230|CD6; CD6 molecule; K06456 CD6 antigen (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	T-cell differentiation antigen CD6 (Precursor) GN=CD6 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: T-cell differentiation antigen CD6 isoform X4 [Canis lupus familiaris]
ENSG00000013810(TACC3)	--	36.35164227	2123	37.08704269	2010	35.27241349	2189	37.63438846	2240	32.1088765	2084	28.62710504	1713	0.987116963	0.046529315	normal	0.986506663	0.030710526	normal	0.847549866	-0.361754987	normal	0.703127386	-0.08839233	normal	--	--	--	"K14283|0|hsa:10460|TACC3, ERIC-1, ERIC1; transforming, acidic coiled-coil containing protein 3; K14283 transforming acidic coiled-coil-containing protein 3 (A)"	RNA transport (ko03013)	--	--	Transforming acidic coiled-coil-containing protein (TACC)	Transforming acidic coiled-coil-containing protein 3 GN=TACC3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transforming acidic coiled-coil-containing protein 3 [Galeopterus variegatus] 
ENSG00000014123(UFL1)	--	6.24633	430	7.15652	488	6.24807	419	8.00257	556	7.93371	546	6.47933	447	0.847272382	0.338848788	normal	0.96145421	0.140182397	normal	0.967151983	0.084736998	normal	0.44436662	0.190362918	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2042)	E3 UFM1-protein ligase 1 GN=UFL1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: E3 UFM1-protein ligase 1 isoform 1 [Ceratotherium simum simum]
ENSG00000014138(POLA2)	--	21.3417341	1066	21.74524001	1052	26.09727868	1296	23.60207833	1146	22.095101	1070	20.10389535	976	0.978699303	0.073465211	normal	0.979778065	0.003045194	normal	0.67073579	-0.416841654	normal	0.59683371	-0.118295707	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Biological Process: DNA replication (GO:0006260);; 	"K02321|0|hsa:23649|POLA2; polymerase (DNA directed), alpha 2, accessory subunit; K02321 DNA polymerase alpha subunit B (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030)	[L]	"Replication, recombination and repair"	DNA polymerase alpha subunit B N-terminal;; DNA polymerase alpha/epsilon subunit B	DNA polymerase alpha subunit B GN=POLA2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase alpha subunit B [Ceratotherium simum simum]
ENSG00000014164(ZC3H3)	--	14.370597	996	13.9727807	953	13.972721	981	14.15926503	965	15.585761	1047	15.484379	1067	0.977049217	-0.07632943	normal	0.973742654	0.114113961	normal	0.974708549	0.11277695	normal	0.856924787	0.05071645	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 3 GN=ZC3H3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	"PREDICTED: zinc finger CCCH domain-containing protein 3, partial [Equus caballus]"
ENSG00000014216(CAPN1)	--	67.74816896	3737	73.80534148	4025	71.88364231	3994	69.15480163	4015	72.01551886	3965	74.5326855	4093	0.991055332	0.072658338	normal	0.991601053	-0.043078167	normal	0.992098242	0.027022784	normal	0.958395189	0.017286776	normal	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K01367|0|hsa:823|CAPN1, CANP, CANP1, CANPL1, muCANP, muCL; calpain 1, (mu/I) large subunit (EC:3.4.22.52); K01367 calpain-1 [EC:3.4.22.52] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Apoptosis (ko04210);; Alzheimer's disease (ko05010)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand"	Calpain-1 catalytic subunit GN=CAPN1 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-1 catalytic subunit [Tupaia chinensis]
ENSG00000014257(ACPP)	--	0.104592633	4	0	0	0	0	0.250687541	8	0.083569239	3	0.177667559	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: acid phosphatase activity (GO:0003993);; 	"K14410|0|pps:100974414|ACPP; acid phosphatase, prostate; K14410 acid phosphatase [EC:3.1.3.2] (A)"	Riboflavin metabolism (ko00740)	[I]	Lipid transport and metabolism	Histidine phosphatase superfamily (branch 2)	PAPf39 (Precursor) GN=ACPP OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: prostatic acid phosphatase [Galeopterus variegatus]
ENSG00000014641(MDH1)	--	190.38398	4382	167.908726	3974	182.0487551	4200	129.2865555	3079	136.393353	3057	137.903829	3171	0.230516339	-0.539732805	normal	0.821570001	-0.399727892	normal	0.778321639	-0.413570925	normal	0.002494569	-0.453063822	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00025|0|hsa:4190|MDH1, HEL-S-32, MDH-s, MDHA, MGC:1375, MOR2; malate dehydrogenase 1, NAD (soluble) (EC:1.1.1.37 1.1.1.96); K00025 malate dehydrogenase [EC:1.1.1.37] (A)"	Citrate cycle (TCA cycle) (ko00020);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; Proximal tubule bicarbonate reclamation (ko04964)	[C]	Energy production and conversion	"lactate/malate dehydrogenase, alpha/beta C-terminal domain;; lactate/malate dehydrogenase, NAD binding domain"	"Malate dehydrogenase, cytoplasmic GN=MDH1 OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"PREDICTED: malate dehydrogenase, cytoplasmic isoform 1 [Ceratotherium simum simum]"
ENSG00000014824(SLC30A9)	--	22.2016859	1060	18.38518796	868	21.97028268	1060	25.10615064	1248	26.21429878	1287	23.0933407	1182	0.959694753	0.204448075	normal	0.190214207	0.546032622	normal	0.971447544	0.148673375	normal	0.086765549	0.293853091	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14696|0|hsa:10463|SLC30A9, C4orf1, GAC63, HUEL, ZNT9; solute carrier family 30 (zinc transporter), member 9; K14696 solute carrier family 30 (zinc transporter), member 9 (A)"	--	[R]	General function prediction only	Cation efflux family	Zinc transporter 9 GN=SLC30A9 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter 9 [Galeopterus variegatus]
ENSG00000014914(MTMR11)	--	4.017735873	209	2.831122	147	3.5332934	184	4.864982742	247	5.099455314	258	4.521254314	234	0.945231578	0.208762932	normal	0.031197633	0.783965503	normal	0.887140445	0.336056557	normal	0.130877663	0.431436442	normal	--	--	--	"K18085|0|hsa:10903|MTMR11, CRA; myotubularin related protein 11; K18085 myotubularin-related protein 10/11/12 (A)"	--	--	--	Myotubularin-like phosphatase domain;; Myotubularin-associated protein	Myotubularin-related protein 11 GN=MTMR11 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: myotubularin-related protein 11 isoform X1 [Galeopterus variegatus]
ENSG00000014919(COX15)	--	28.55766	1561	28.70146	1664	30.33394	1669	30.95813	1702	30.55935	1681	26.92965	1540	0.982118394	0.093839769	normal	0.984775455	-0.006756158	normal	0.97953786	-0.124227827	normal	0.971095564	-0.012895673	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Biological Process: heme a biosynthetic process (GO:0006784);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Biological Process: oxidation-reduction process (GO:0055114);; "	K02259|0|ptr:744451|COX15; cytochrome c oxidase assembly protein COX15 homolog; K02259 cytochrome c oxidase assembly protein subunit 15 (A)	Oxidative phosphorylation (ko00190);; Porphyrin and chlorophyll metabolism (ko00860)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cytochrome oxidase assembly protein	Cytochrome c oxidase assembly protein COX15 homolog GN=COX15 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cytochrome c oxidase assembly protein COX15 homolog isoform X1 [Galeopterus variegatus]
ENSG00000015133(CCDC88C)	--	2.874952176	482	2.263970764	370	2.231214599	384	2.710244163	370	2.518775347	405	1.850236401	327	0.714720277	-0.410840395	normal	0.963004498	0.108545938	normal	0.931889646	-0.239085605	normal	0.49764287	-0.187145618	normal	--	--	--	--	--	[S]	Function unknown	HOOK protein	Protein Daple GN=CCDC88C OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein Daple [Ceratotherium simum simum]
ENSG00000015153(YAF2)	--	11.22188234	309	26.793748	346	14.03615835	334	11.21105761	376	22.36212357	439	17.66860829	431	0.926269707	0.251160044	normal	0.874504698	0.320775111	normal	0.828063477	0.358117255	normal	0.193053086	0.312535898	normal	--	--	--	K11468|7.44421e-84|ptr:466958|YAF2; YY1 associated factor 2; K11468 YY1-associated factor 2 (A)	--	[K]	Transcription	Zn-finger in Ran binding protein and others	YY1-associated factor 2 GN=YAF2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: YY1-associated factor 2 isoform X1 [Chrysochloris asiatica]
ENSG00000015171(ZMYND11)	--	23.29636696	1764	26.34823049	2013	23.09353942	1737	23.54759566	1802	21.66665594	1627	24.60251888	1859	0.985788471	-8.37E-05	normal	0.89751379	-0.328284567	normal	0.983512669	0.089562189	normal	0.726846246	-0.081696246	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	PWWP domain;; Bromodomain	Zinc finger MYND domain-containing protein 11 GN=ZMYND11 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger MYND domain-containing protein 11-like isoform X1 [Chrysochloris asiatica]
ENSG00000015285(WAS)	--	0.1458144	6	0.5852084	13	0.166180841	6	0.246460815	10	0.355673925	14	0.168135309	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; 	K05747|0|pps:100977168|WAS; Wiskott-Aldrich syndrome; K05747 Wiskott-Aldrich syndrome protein (A)	Chemokine signaling pathway (ko04062);; Adherens junction (ko04520);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132);; Choline metabolism in cancer (ko05231)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	WH1 domain;; P21-Rho-binding domain;; WH2 motif	Wiskott-Aldrich syndrome protein GN=WAS OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: wiskott-Aldrich syndrome protein [Galeopterus variegatus]
ENSG00000015413(DPEP1)	--	0.270603357	9	0.370298887	7	0.413541479	3	0.033620037	1	0.03300326	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: dipeptidase activity (GO:0016805);; 	"K01273|0|hsa:1800|DPEP1, MBD1, MDP, RDP; dipeptidase 1 (renal) (EC:3.4.13.19); K01273 membrane dipeptidase [EC:3.4.13.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Membrane dipeptidase (Peptidase family M19)	Dipeptidase 1 (Precursor) GN=DPEP1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dipeptidase 1 [Ceratotherium simum simum]
ENSG00000015475(BID)	--	29.013664	683	32.960279	791	32.36197711	754	34.7403549	840	31.3600545	839	32.971467	818	0.922094415	0.267128869	normal	0.975001773	0.063448767	normal	0.971570435	0.109034868	normal	0.533590558	0.143197678	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: positive regulation of apoptotic process (GO:0043065);; 	K04726|1.29534e-148|ptr:458635|BID; BH3 interacting domain death agonist; K04726 BH3 interacting domain death agonist (A)	Sphingolipid signaling pathway (ko04071);; p53 signaling pathway (ko04115);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Tuberculosis (ko05152);; Pathways in cancer (ko05200);; Viral myocarditis (ko05416)	--	--	BH3 interacting domain (BID)	BH3-interacting domain death agonist p11 GN=BID OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: BH3-interacting domain death agonist [Equus caballus] 
ENSG00000015479(MATR3)	--	88.29635573	6288	99.64102365	7268	103.8610961	6460	94.99264008	7019	88.39274178	6471	89.51407932	6312	0.992653648	0.127802457	normal	0.989109295	-0.188954604	normal	0.994379612	-0.041718521	normal	0.899311644	-0.037150219	normal	--	--	--	"K13213|0|hsa:9782|MATR3, ALS21, MPD2, VCPDM; matrin 3; K13213 matrin 3 (A)"	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Matrin-3 GN=MATR3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	matrin-3 [Oryctolagus cuniculus] 
ENSG00000015520(NPC1L1)	--	0	0	0.059392933	5	0	0	0	0	0.066506783	3	0.028266862	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K14461|0|hsa:29881|NPC1L1, NPC11L1; NPC1-like 1; K14461 Niemann-Pick C1-like protein 1 (A)"	Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Patched family;; Sterol-sensing domain of SREBP cleavage-activation;; Putative binding domain	Niemann-Pick C1-like protein 1 (Precursor) GN=NPC1L1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	Niemann-Pick C1-like protein 1 [Tupaia chinensis]
ENSG00000015532(XYLT2)	--	20.74609144	1503	16.78855172	1228	19.08366621	1412	18.173499	1304	15.48806122	1109	15.43448484	1090	0.95319723	-0.235474695	normal	0.968396911	-0.168259588	normal	0.779647461	-0.381237316	normal	0.130098297	-0.263764967	normal	--	--	Biological Process: glycosaminoglycan biosynthetic process (GO:0006024);; Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; Molecular Function: protein xylosyltransferase activity (GO:0030158);; 	"K00771|0|hsa:64132|XYLT2, PXYLT2, XT-II, XT2, xylT-II; xylosyltransferase II (EC:2.4.2.26); K00771 protein xylosyltransferase [EC:2.4.2.26] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532);; Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[G]	Carbohydrate transport and metabolism	Xylosyltransferase C terminal;; Core-2/I-Branching enzyme	Xylosyltransferase 2 GN=XYLT2 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: xylosyltransferase 2 [Mustela putorius furo] 
ENSG00000015568(RGPD5)	--	0.017473178	1	0.007551169	1	0.18415835	1	0.0150445	2	0.016912868	0	0.01735326	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:84220|RGPD5, BS-63, BS63, HEL161, RGP5; RANBP2-like and GRIP domain containing 5; K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; GRIP domain;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RANBP2-like and GRIP domain-containing protein 5/6 GN=RGPD6 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ceratotherium simum simum]
ENSG00000015676(NUDCD3)	--	10.51930982	1828	10.9016212	1915	11.39918442	1986	13.2704966	2277	12.79710232	2195	14.19492255	2465	0.937756973	0.285820364	normal	0.976306489	0.175320594	normal	0.928125452	0.303222949	normal	0.134357373	0.255152248	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	N-terminal conserved domain of Nudc.;; CS domain	NudC domain-containing protein 3 GN=NUDCD3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: nudC domain-containing protein 3 isoform X1 [Tupaia chinensis] 
ENSG00000016082(ISL1)	--	0	0	0	0	0	0	0	0	0	0	0.0230773	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09370|0|umr:103664640|ISL1; ISL LIM homeobox 1; K09370 insulin gene enhancer protein ISL-1 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[R]	General function prediction only	LIM domain;; Homeobox domain	Insulin gene enhancer protein ISL-1 GN=ISL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"Insulin enhancer protein ISL-1, partial [Bos mutus]"
ENSG00000016391(CHDH)	--	3.194497731	315	2.850785709	302	3.13538259	317	3.519395	396	5.325096	432	3.336655	387	0.896477034	0.298017626	normal	0.495939601	0.492982152	normal	0.911013243	0.278355576	normal	0.128132186	0.358316784	normal	[E]	Amino acid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on CH-OH group of donors (GO:0016614);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00108|0|hsa:55349|CHDH; choline dehydrogenase (EC:1.1.99.1); K00108 choline dehydrogenase [EC:1.1.99.1] (A)	"Glycine, serine and threonine metabolism (ko00260)"	[R]	General function prediction only	GMC oxidoreductase;; GMC oxidoreductase	"Choline dehydrogenase, mitochondrial (Precursor) GN=CHDH OS=Homo sapiens (Human) PE=2 SV=2"	C	Energy production and conversion	"PREDICTED: choline dehydrogenase, mitochondrial [Elephantulus edwardii]"
ENSG00000016402(IL20RA)	--	0.036328559	2	0	0	0.019882903	0	0.039562229	2	0.440416736	7	0.019877299	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K05136|0|ggo:101145811|IL20RA; interleukin-20 receptor subunit alpha; K05136 interleukin 20 receptor alpha (A)	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	"Tissue factor;; Interferon-alpha/beta receptor, fibronectin type III"	Interleukin-20 receptor subunit alpha (Precursor) GN=IL20RA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_003080 [Ailuropoda melanoleuca]
ENSG00000016864(GLT8D1)	--	20.37777001	611	17.77038409	551	19.01532397	615	18.75493311	637	16.40327907	557	17.710588	555	0.973722108	0.029216775	normal	0.972137456	-0.005785755	normal	0.960827095	-0.155986114	normal	0.894182217	-0.044437105	normal	[M]	Cell wall/membrane/envelope biogenesis	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	--	--	--	--	Glycosyl transferase family 8	Glycosyltransferase 8 domain-containing protein 1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: glycosyltransferase 8 domain-containing protein 1 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000017260(ATP2C1)	--	26.69261598	1793	25.00869856	1724	28.43014353	1941	31.10076397	2108	26.61419493	1794	33.20199014	2169	0.970348607	0.202506948	normal	0.984930444	0.035962633	normal	0.979789347	0.151826539	normal	0.522494736	0.132572078	normal	[P]	Inorganic ion transport and metabolism	--	"K01537|0|cjc:100411487|ATP2C1; ATPase, Ca++ transporting, type 2C, member 1; K01537 Ca2+-transporting ATPase [EC:3.6.3.8] (A)"	--	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Calcium-transporting ATPase type 2C member 1 GN=ATP2C1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: calcium-transporting ATPase type 2C member 1 isoform 1 [Ceratotherium simum simum]
ENSG00000017427(IGF1)	--	0	0	0	0	0	0	0.008930001	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05459|4.35657e-139|pps:100982978|IGF1; insulin-like growth factor 1 (somatomedin C); K05459 insulin-like growth factor 1 (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Oocyte meiosis (ko04114);; p53 signaling pathway (ko04115);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Aldosterone-regulated sodium reabsorption (ko04960);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	--	--	Insulin/IGF/Relaxin family	Insulin-like growth factor I (Precursor) GN=IGF1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: insulin-like growth factor I isoform X1 [Equus caballus] 
ENSG00000017483(SLC38A5)	--	0.10216807	3	0.033788567	1	0.033219449	0	0	0	0.132622093	3	0.11018491	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K14992|0|hsa:92745|SLC38A5, JM24, SN2, SNAT5, pp7194; solute carrier family 38, member 5; K14992 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 5 (A)"	GABAergic synapse (ko04727)	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Sodium-coupled neutral amino acid transporter 5 GN=SLC38A5 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: sodium-coupled neutral amino acid transporter 5 isoform X1 [Galeopterus variegatus]
ENSG00000017797(RALBP1)	--	19.515399	1595	20.92601318	1670	20.87143438	1689	20.6097159	1697	20.55372698	1663	20.91063316	1686	0.983969465	0.058543203	normal	0.984536425	-0.027461572	normal	0.985237879	-0.010846514	normal	0.988283415	0.005385052	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K08773|0|hsa:10928|RALBP1, RIP1, RLIP1, RLIP76; ralA binding protein 1; K08773 RalA-binding protein 1 (A)"	Ras signaling pathway (ko04014);; Pathways in cancer (ko05200);; Pancreatic cancer (ko05212)	[T]	Signal transduction mechanisms	RhoGAP domain	RalA-binding protein 1 GN=RALBP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ralA-binding protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000018189(RUFY3)	--	5.577807796	451	7.439857563	376	5.023996211	420	4.937094454	423	6.164372473	483	5.13998265	433	0.963019998	-0.122869699	normal	0.852327876	0.338659445	normal	0.969781528	0.035560148	normal	0.80221314	0.081705566	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	RUN domain;; FYVE zinc finger	Protein RUFY3 GN=RUFY3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein RUFY3 isoform X5 [Equus przewalskii]
ENSG00000018236(CNTN1)	--	103.0686613	7651	98.3583388	7671	94.829063	6654	145.6529852	10819	163.046626	12467	153.1976044	11693	0.70453403	0.468935128	normal	0.020639464	0.679095233	normal	0.000314121	0.80492011	normal	2.46E-05	0.649409799	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06759|0|pps:100991427|CNTN1; contactin 1; K06759 contactin 1 (A)	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Contactin-1 (Precursor) GN=CNTN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: contactin-1 isoform X1 [Tupaia chinensis] 
ENSG00000018280(SLC11A1)	--	0.164581	11	0.190867	13	0.244859	16	0.0446656	3	0.0726346	4	0.0736876	5	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K12347|0|hsa:6556|SLC11A1, LSH, NRAMP, NRAMP1; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1; K12347 natural resistance-associated macrophage protein (A)"	Lysosome (ko04142);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Natural resistance-associated macrophage protein	Natural resistance-associated macrophage protein 1 GN=SLC11A1 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: natural resistance-associated macrophage protein 1 [Galeopterus variegatus]
ENSG00000018408(WWTR1)	--	55.66435062	3944	52.27488079	4160	53.02811245	3770	44.63014972	3632	48.51863342	3869	41.33442997	3415	0.987088644	-0.14966683	normal	0.988941902	-0.126001847	normal	0.986434483	-0.150906755	normal	0.489129199	-0.142820213	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K16820|0|ptr:460772|WWTR1; WW domain containing transcription regulator 1; K16820 WW domain-containing transcription regulator protein 1 (A)	Hippo signaling pathway (ko04390)	[O]	"Posttranslational modification, protein turnover, chaperones"	WW domain	WW domain-containing transcription regulator protein 1 GN=WWTR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: WW domain-containing transcription regulator protein 1 [Galeopterus variegatus]
ENSG00000018510(AGPS)	--	28.20659	2244	27.62291421	2326	28.92983888	2311	23.47789026	2086	22.87667801	1973	18.9721003	1599	0.982136785	-0.13606912	normal	0.95472014	-0.25870383	normal	0.193985086	-0.539212092	normal	0.061058861	-0.304252606	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00803|0|mcf:102140514|AGPS; alkylglycerone phosphate synthase; K00803 alkyldihydroxyacetonephosphate synthase [EC:2.5.1.26] (A)	Ether lipid metabolism (ko00565);; Peroxisome (ko04146)	[R]	General function prediction only	"FAD linked oxidases, C-terminal domain;; FAD binding domain"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal (Precursor) GN=AGPS OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"Alkyldihydroxyacetonephosphate synthase, peroxisomal, partial [Bos mutus]"
ENSG00000018610(CXorf56)	--	12.13271637	509	12.48853032	520	11.00582186	460	12.83924606	555	12.59473127	502	12.65846804	515	0.968261159	0.093718895	normal	0.968925412	-0.072037574	normal	0.959131419	0.154167891	normal	0.864109229	0.056607134	normal	--	--	--	--	--	[S]	Function unknown	--	UPF0428 protein CXorf56 GN=CXorf56 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0428 protein CXorf56 homolog isoform X2 [Echinops telfairi] 
ENSG00000018625(ATP1A2)	--	0.072153725	7	0.06124126	6	0.06526208	7	0.020640071	2	0.020110214	1	0.030713876	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K01539|0|pps:100968564|ATP1A2; ATPase, Na+/K+ transporting, alpha 2 polypeptide; K01539 sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Insulin secretion (ko04911);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Proximal tubule bicarbonate reclamation (ko04964);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Carbohydrate digestion and absorption (ko04973);; Protein digestion and absorption (ko04974);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Sodium/potassium-transporting ATPase subunit alpha-2 (Precursor) GN=ATP1A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium-transporting ATPase subunit alpha-2 isoform X2 [Mustela putorius furo] 
ENSG00000018699(TTC27)	--	13.86814295	710	15.24591957	782	13.96060639	708	10.4949463	542	10.09367765	515	9.459193981	479	0.66319847	-0.419316257	normal	0.061602291	-0.622527741	normal	0.147514506	-0.570523903	normal	0.001746333	-0.53999486	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3"	Tetratricopeptide repeat protein 27 GN=TTC27 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 27 [Ceratotherium simum simum]
ENSG00000018869(ZNF582)	--	0.912531422	41	1.051029	41	1.352326887	36	0.986566	24	0.570757411	21	1.5240529	34	0.894940486	-0.765489079	normal	0.781271567	-0.937493077	normal	0.982603967	-0.086992712	normal	0.354893071	-0.599265571	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:147948|ZNF582; zinc finger protein 582; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; Zinc-finger of C2H2 type;; BED zinc finger"	Zinc finger protein 582 GN=ZNF582 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 582 [Equus caballus] 
ENSG00000019102(VSIG2)	--	0	0	0	0	0.0492532	0	0.151744	3	0.0499772	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	V-set and immunoglobulin domain-containing protein 2 (Precursor) GN=VSIG2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	hypothetical protein PANDA_013278 [Ailuropoda melanoleuca]
ENSG00000019144(PHLDB1)	--	3.183216388	276	3.235706594	230	3.607642434	276	6.9413244	581	9.25498995	734	4.947627753	344	4.27E-06	1.038964724	up	8.88E-16	1.646326117	up	0.892056985	0.307934661	normal	0.045161847	1.063018208	normal	--	--	--	--	--	--	--	PH domain	Pleckstrin homology-like domain family B member 1 GN=PHLDB1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: pleckstrin homology-like domain family B member 1 isoform X1 [Galeopterus variegatus]
ENSG00000019169(MARCO)	--	0.092473946	4	0	0	0	0	0	0	0.022563521	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	"K13884|2.67432e-127|hsa:8685|MARCO, SCARA2; macrophage receptor with collagenous structure; K13884 macrophage receptor with collagenous structure (A)"	Phagosome (ko04145)	--	--	Collagen triple helix repeat (20 copies);; Scavenger receptor cysteine-rich domain	Macrophage receptor MARCO GN=MARCO OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: macrophage receptor MARCO [Odobenus rosmarus divergens]
ENSG00000019186(CYP24A1)	--	398.1329405	23587	367.3781104	21696	327.8130309	19375	316.9401	18352	492.715005	28716	288.7154521	17000	0.948157809	-0.392857802	normal	0.963332094	0.38297589	normal	0.994779484	-0.196936583	normal	0.959389613	-0.034598445	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07436|0|hsa:1591|CYP24A1, CP24, CYP24, HCAI, P450-CC24; cytochrome P450, family 24, subfamily A, polypeptide 1 (EC:1.14.13.126); K07436 vitamin D3 24-hydroxylase [EC:1.14.13.126] (A)"	Steroid biosynthesis (ko00100);; MicroRNAs in cancer (ko05206)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	"1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (Precursor) GN=CYP24A1 OS=Homo sapiens (Human) PE=1 SV=2"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial-like isoform X1 [Myotis lucifugus]"
ENSG00000019485(PRDM11)	--	4.226268779	425	5.023996215	475	4.012814784	388	3.307793481	330	3.081912259	344	4.240856786	426	0.763788529	-0.394206804	normal	0.500214042	-0.485122063	normal	0.962129029	0.126036365	normal	0.318747239	-0.248342846	normal	--	--	--	--	--	--	--	--	PR domain-containing protein 11 GN=PRDM11 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: PR domain-containing protein 11 [Galeopterus variegatus]
ENSG00000019505(SYT13)	--	1.227761166	114	1.126902353	101	1.188231	107	19.11956611	1776	20.35168449	1826	10.99243358	1022	0	3.9128449	up	0	4.134752678	up	0	3.229370549	up	3.25E-12	3.821483837	up	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; Phosphoinositide 3-kinase C2	Synaptotagmin-13 GN=SYT13 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-13 [Myotis lucifugus]
ENSG00000019549(SNAI2)	--	0.538675117	16	0.364874419	13	0.534378733	16	2.193886925	70	2.254725767	72	0.997094054	32	3.99E-05	1.999170028	up	1.14E-06	2.320620891	up	0.889441174	0.928576256	normal	0.003356677	1.928303939	up	[R]	General function prediction only	--	K05706|5.03064e-179|ptr:464169|SNAI2; snail family zinc finger 2; K05706 snail 2 (A)	Hippo signaling pathway (ko04390);; Adherens junction (ko04520)	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Drought induced 19 protein (Di19), zinc-binding;; BED zinc finger"	Zinc finger protein SNAI2 GN=SNAI2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein SNAI2 [Myotis brandtii] 
ENSG00000019582(CD74)	--	0	0	0	0	0.254933425	7	0.432539356	3	0.11309056	1	0.047212602	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: antigen processing and presentation (GO:0019882);; Molecular Function: MHC class II protein binding (GO:0042289);; 	"K06505|0|mcf:102131412|CD74; CD74 molecule, major histocompatibility complex, class II invariant chain; K06505 CD74 antigen (A)"	Antigen processing and presentation (ko04612);; Tuberculosis (ko05152);; Herpes simplex infection (ko05168)	--	--	"CLIP, MHC2 interacting;; Class II MHC-associated invariant chain trimerisation domain;; Thyroglobulin type-1 repeat"	HLA class II histocompatibility antigen gamma chain GN=CD74 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: HLA class II histocompatibility antigen gamma chain [Ursus maritimus]
ENSG00000019995(ZRANB1)	--	4.246546	414	5.27221	522	4.12473	401	4.506699	444	4.95446	482	5.295143	517	0.968052981	0.069846325	normal	0.961800204	-0.136032949	normal	0.822334735	0.357081577	normal	0.775551266	0.0890326	normal	--	--	--	"K11862|0|ptr:450809|ZRANB1; zinc finger, RAN-binding domain containing 1; K11862 ubiquitin thioesterase ZRANB1 [EC:3.4.19.12] (A)"	--	[T]	Signal transduction mechanisms	OTU-like cysteine protease;; Zn-finger in Ran binding protein and others	Ubiquitin thioesterase ZRANB1 GN=ZRANB1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ubiquitin thioesterase ZRANB1 isoform X1 [Galeopterus variegatus]
ENSG00000020129(NCDN)	--	10.146509	649	10.74333647	695	10.33521504	646	11.867914	723	11.572669	670	12.84924057	745	0.967789974	0.124665206	normal	0.972159676	-0.074114176	normal	0.953153674	0.196985075	normal	0.764410862	0.082273783	normal	--	--	--	--	--	[S]	Function unknown	Neurochondrin	Neurochondrin GN=NCDN OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: neurochondrin isoform X1 [Condylura cristata]
ENSG00000020181(ADGRA2)	--	1.55682544	190	1.10206934	143	1.4382568	175	1.615925503	193	2.888394548	352	2.061223982	251	0.967043482	-0.008165323	normal	2.34E-07	1.269299565	up	0.58915586	0.508353878	normal	0.172227103	0.627814937	normal	[S]	Function unknown	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: protein binding (GO:0005515);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08461|0|hsa:25960|GPR124, TEM5, ADGRA2; G protein-coupled receptor 124; K08461 G protein-coupled receptor 124 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; 7 transmembrane receptor (Secretin family);; Leucine Rich repeats (2 copies);; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain;; Leucine Rich Repeat	G-protein coupled receptor 124 (Precursor) GN=GPR124 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 124 isoform X1 [Condylura cristata]
ENSG00000020256(ZFP64)	--	9.62995553	559	10.67572689	610	10.55894621	560	8.115197914	440	10.7335827	587	9.431822	559	0.785921571	-0.375011993	normal	0.970392923	-0.076681485	normal	0.972953886	-0.010840685	normal	0.570208324	-0.145054362	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc-finger domain;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	"Zinc finger protein 64 homolog, isoforms 1 and 2 GN=ZFP64 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: zinc finger protein 64 homolog, isoforms 3 and 4 isoform 1 [Odobenus rosmarus divergens]"
ENSG00000020426(MNAT1)	--	43.651594	905	41.53171801	759	46.18028422	858	44.72839454	894	43.31283264	886	48.49517728	854	0.977402399	-0.048392562	normal	0.954174721	0.201408535	normal	0.977729948	-0.015006508	normal	0.890265455	0.041461896	normal	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	--	K10842|0|ptr:452954|MNAT1; MNAT CDK-activating kinase assembly factor 1; K10842 CDK-activating kinase assembly factor MAT1 (A)	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420)	[O]	"Posttranslational modification, protein turnover, chaperones"	CDK-activating kinase assembly factor MAT1	CDK-activating kinase assembly factor MAT1 GN=MNAT1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: CDK-activating kinase assembly factor MAT1-like [Tupaia chinensis]
ENSG00000020577(SAMD4A)	--	4.950570841	619	6.414842983	806	5.644609495	641	6.063106178	829	4.120230051	535	4.595190603	611	0.744413674	0.389761937	normal	0.074070377	-0.611249295	normal	0.971581689	-0.077256707	normal	0.857893181	-0.08756707	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[JT]	"Translation, ribosomal structure and biogenesis;; Signal transduction mechanisms"	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Protein Smaug homolog 1 GN=SAMD4A OS=Homo sapiens (Human) PE=1 SV=3	JT	"Translation, ribosomal structure and biogenesis;; Signal transduction mechanisms"	PREDICTED: protein Smaug homolog 1 isoform X1 [Eptesicus fuscus]
ENSG00000020633(RUNX3)	--	9.095425122	679	7.85548873	582	7.694283151	577	2.531132304	187	2.577528747	192	2.700068652	203	0	-1.882500637	down	3.08E-14	-1.613652919	down	8.96E-13	-1.508410021	down	5.27E-21	-1.680109031	down	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09279|0|hsa:864|RUNX3, AML2, CBFA3, PEBP2aC; runt-related transcription factor 3; K09279 runt-related transcription factor 3 (A)"	--	[K]	Transcription	Runt domain;; Runx inhibition domain	Runt-related transcription factor 3 GN=RUNX3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: runt-related transcription factor 3 [Vicugna pacos]
ENSG00000020922(MRE11)	--	12.35657133	828	10.24777977	772	11.51168107	757	9.575369583	748	10.35648162	672	10.75989291	776	0.960285791	-0.177078841	normal	0.945127539	-0.2211015	normal	0.976229939	0.027417811	normal	0.608901852	-0.123285573	normal	[L]	"Replication, recombination and repair"	Molecular Function: endonuclease activity (GO:0004519);; Cellular Component: nucleus (GO:0005634);; Biological Process: double-strand break repair (GO:0006302);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: manganese ion binding (GO:0030145);; 	K10865|0|pps:100981052|MRE11A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); K10865 double-strand break repair protein MRE11 (A)	Homologous recombination (ko03440);; Non-homologous end-joining (ko03450)	[L]	"Replication, recombination and repair"	Mre11 DNA-binding presumed domain;; Calcineurin-like phosphoesterase;; Calcineurin-like phosphoesterase superfamily domain	Double-strand break repair protein MRE11A GN=MRE11A OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: double-strand break repair protein MRE11A isoformX2 [Canis lupus familiaris] 
ENSG00000021300(PLEKHB1)	--	1.325358179	31	0.91093166	34	1.115258896	39	0.953355561	28	1.441404881	33	1.27690569	44	0.983954167	-0.168862694	normal	0.982428779	-0.061709101	normal	0.978970713	0.159897617	normal	1	-0.005707828	normal	--	--	--	--	--	--	--	--	Pleckstrin homology domain-containing family B member 1 GN=PLEKHB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family B member 1 isoform X1 [Camelus ferus]
ENSG00000021355(SERPINB1)	--	20.06810099	866	16.68229927	714	17.2958	730	37.05602	1604	38.527083	1659	37.62303372	1626	6.65E-05	0.857268907	normal	7.02E-10	1.19318579	up	2.47E-09	1.145435412	up	1.25E-14	1.060418655	up	--	--	--	"K13963|0|hsa:1992|SERPINB1, EI, ELANH2, HEL57, LEI, M/NEI, MNEI, PI-2, PI2; serpin peptidase inhibitor, clade B (ovalbumin), member 1; K13963 serpin B (A)"	Amoebiasis (ko05146)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Leukocyte elastase inhibitor GN=SERPINB1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: leukocyte elastase inhibitor [Galeopterus variegatus] 
ENSG00000021488(SLC7A9)	--	0.28564179	7	0.08042831	2	0.234107263	5	0.322045405	8	0.27169016	6	0.258012531	6	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13868|0|hsa:11136|SLC7A9, BAT1, CSNU3; solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9; K13868 solute carrier family 7 (L-type amino acid transporter), member 9 (A)"	Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease	"b(0,+)-type amino acid transporter 1 GN=SLC7A9 OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: B(0,+)-type amino acid transporter 1 [Eptesicus fuscus]"
ENSG00000021574(SPAST)	--	10.2263977	789	11.26714012	862	11.4467	868	8.943751	645	9.474002668	670	7.688994	593	0.871028573	-0.320865931	normal	0.766168723	-0.384186576	normal	0.162454036	-0.556773472	normal	0.01448805	-0.422112112	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	K13254|0|ptr:459133|SPAST; spastin; K13254 spastin [EC:3.6.4.3] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; MIT (microtubule interacting and transport) domain;; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (dynein-related subfamily)	Spastin {ECO:0000255|HAMAP-Rule:MF_03021} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: spastin isoform X1 [Vicugna pacos] 
ENSG00000021645(NRXN3)	--	0.113124363	8	0.456856238	34	0.201344074	13	0.297091075	21	0.201661318	16	0.378796421	28	0.910248624	1.213437628	normal	0.79527844	-1.039996066	normal	0.891539149	1.016393809	normal	0.890794781	0.219537057	normal	--	--	--	K07377|0|mcf:102115292|NRXN3; neurexin 3; K07377 neurexin (A)	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain;; Syndecan domain	Neurexin-3 (Precursor) GN=NRXN3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: neurexin-3-beta isoform X1 [Tupaia chinensis]
ENSG00000021762(OSBPL5)	--	5.528454739	396	4.532448903	300	3.86135778	321	2.498061848	204	4.366704255	310	2.696535087	205	9.37E-05	-0.982350228	normal	0.966664802	0.025751457	normal	0.119001597	-0.651368144	normal	0.092125235	-0.521291853	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Oxysterol-binding protein;; PH domain	Oxysterol-binding protein-related protein 5 GN=OSBPL5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 5 [Ceratotherium simum simum]
ENSG00000021776(AQR)	--	14.08678368	2322	13.8144274	2394	13.42240552	2293	13.7746028	2414	15.31890253	2664	13.64010263	2377	0.988218524	0.025209081	normal	0.983967639	0.132664902	normal	0.987798651	0.043585872	normal	0.781719923	0.067767184	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K12874|0|hsa:9716|AQR, IBP160, fSAP164; aquarius intron-binding spliceosomal factor; K12874 intron-binding protein aquarius (A)"	Spliceosome (ko03040)	[L]	"Replication, recombination and repair"	AAA domain;; AAA domain;; Part of AAA domain	Intron-binding protein aquarius GN=AQR OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: intron-binding protein aquarius isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000021826(CPS1)	--	0.288224522	17	0.178607942	15	0.458441052	21	1.584298028	177	2.277786	226	3.316499262	354	0	3.238358432	up	0	3.763958499	up	0	3.973119508	up	2.22E-07	3.817638741	up	[EF]	Amino acid transport and metabolism;; Nucleotide transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; 	"K01948|0|hsa:1373|CPS1, CPSASE1, PHN; carbamoyl-phosphate synthase 1, mitochondrial (EC:6.3.4.16); K01948 carbamoyl-phosphate synthase (ammonia) [EC:6.3.4.16] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; Nitrogen metabolism (ko00910);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[R]	General function prediction only	"Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase small chain, CPSase domain;; Carbamoyl-phosphate synthetase large chain, oligomerisation domain;; Glutamine amidotransferase class-I;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; ATP-grasp domain;; MGS-like domain;; ATP-grasp domain;; D-ala D-ala ligase C-terminus;; ATP-grasp domain"	"Carbamoyl-phosphate synthase [ammonia], mitochondrial (Precursor) GN=CPS1 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: carbamoyl-phosphate synthase [ammonia], mitochondrial [Felis catus]"
ENSG00000022267(FHL1)	--	68.49668664	2514	42.63867554	1680	64.18711972	2264	15.34058196	547	20.38042153	662	16.44589686	558	0	-2.227986306	down	4.50E-13	-1.362956735	down	0	-2.025873063	down	1.87E-10	-1.89060022	down	--	--	--	K14365|0|mcf:101926241|uncharacterized LOC101926241; K14365 four and a half LIM domains protein 1 (A)	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	LIM domain	Four and a half LIM domains protein 1 GN=FHL1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: four and a half LIM domains protein 1 isoform X1 [Ochotona princeps]
ENSG00000022277(RTFDC1)	--	33.90776	1335	32.78555812	1360	33.94291	1350	33.36096	1304	36.7886641	1460	35.90053	1388	0.981269619	-0.064652844	normal	0.980825408	0.080848383	normal	0.982793503	0.031721673	normal	0.960276559	0.016708028	normal	--	--	--	--	--	[S]	Function unknown	Rtf2 RING-finger	Protein RTF2 homolog OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein RTF2 homolog isoform X1 [Pantholops hodgsonii]
ENSG00000022556(NLRP2)	--	24.05569619	1748	20.62228578	1567	26.13705651	1959	19.16263916	1440	22.83281523	1625	21.75606012	1637	0.908210272	-0.310167695	normal	0.984023749	0.030978622	normal	0.944986796	-0.26712861	normal	0.319425557	-0.186067571	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	NACHT domain;; Leucine Rich repeat;; PAAD/DAPIN/Pyrin domain	"NACHT, LRR and PYD domains-containing protein 2 GN=NLRP2 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: LOW QUALITY PROTEIN: NACHT, LRR and PYD domains-containing protein 2-like [Galeopterus variegatus]"
ENSG00000022567(SLC45A4)	--	6.468260674	732	7.5467925	839	5.969664419	800	4.868839774	492	5.253000394	477	7.838221598	942	0.082447288	-0.602463972	normal	0.000455908	-0.83408636	normal	0.946363551	0.227039693	normal	0.53719273	-0.330378362	normal	--	--	--	"K15378|0|ptr:464425|SLC45A4; solute carrier family 45, member 4; K15378 solute carrier family 45, member 1/2/4 (A)"	--	[G]	Carbohydrate transport and metabolism	MFS/sugar transport protein	Solute carrier family 45 member 4 GN=SLC45A4 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 45 member 4 isoform X1 [Canis lupus familiaris]
ENSG00000022840(RNF10)	--	49.32995215	3214	50.08692639	3312	49.276035	3281	56.821735	3748	61.7081297	3871	64.87334119	4301	0.981702654	0.190834222	normal	0.980120545	0.203491062	normal	0.856701952	0.382090826	normal	0.129902171	0.260725423	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 10 GN=RNF10 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 10 isoform X1 [Equus przewalskii]
ENSG00000022976(ZNF839)	--	6.68867508	342	6.68853164	346	6.847890582	361	6.490976489	329	6.672044209	332	6.978302743	351	0.965034976	-0.08634546	normal	0.964660388	-0.080655434	normal	0.967866215	-0.048612713	normal	0.842571985	-0.07271789	normal	--	--	--	--	--	--	--	--	Zinc finger protein 839 GN=ZNF839 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 839 [Ceratotherium simum simum]
ENSG00000023041(ZDHHC6)	--	22.970235	849	24.332765	917	22.559935	822	21.476355	831	22.38115	839	22.40939	862	0.975977858	-0.061635591	normal	0.967159044	-0.149419754	normal	0.976165947	0.060149962	normal	0.853759328	-0.052780061	normal	--	--	--	"K18932|0|ptr:450740|ZDHHC6; zinc finger, DHHC-type containing 6; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase;; Variant SH3 domain	Palmitoyltransferase ZDHHC6 GN=ZDHHC6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC6 isoform X1 [Vicugna pacos]
ENSG00000023171(GRAMD1B)	--	26.53535668	2542	22.12569099	1959	22.56556637	2251	17.04166104	2124	23.64392752	2895	23.66940905	2369	0.939554371	-0.289820574	normal	0.219724909	0.5416734	normal	0.987110654	0.065377881	normal	0.746203194	0.109174136	normal	--	--	--	--	--	[S]	Function unknown	GRAM domain	GRAM domain-containing protein 1B GN=GRAMD1B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: GRAM domain-containing protein 1B isoform X3 [Equus przewalskii]
ENSG00000023191(RNH1)	--	82.58999763	2708	80.12773121	2649	87.23480301	2894	85.761579	2778	82.026694	2622	74.96752311	2456	0.989551954	0.005983245	normal	0.98865329	-0.036185952	normal	0.964989085	-0.244906715	normal	0.68604178	-0.092188703	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16634|0|hsa:6050|RNH1, RAI, RNH; ribonuclease/angiogenin inhibitor 1; K16634 ribonuclease inhibitor (A)"	--	[S]	Function unknown	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeat	Ribonuclease inhibitor GN=RNH1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ribonuclease inhibitor [Galeopterus variegatus]
ENSG00000023228(NDUFS1)	--	43.0114428	2897	42.6447714	3001	44.6144022	2927	28.1889567	2026	32.9441404	2161	27.748492	1984	0.178497648	-0.546409181	normal	0.423096376	-0.494875489	normal	0.117399264	-0.568942802	normal	0.000176384	-0.537322	normal	[C]	Energy production and conversion	"Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on NAD(P)H (GO:0016651);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K03934|0|nle:100581296|NDUFS1; NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase); K03934 NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:1.6.5.3 1.6.99.3] (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Molybdopterin oxidoreductase;; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region;; 2Fe-2S iron-sulfur cluster binding domain;; Domain of unknown function (DUF1982);; 2Fe-2S iron-sulfur cluster binding domain	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial (Precursor) GN=NDUFS1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1 [Sorex araneus]"
ENSG00000023287(RB1CC1)	--	19.0278	2142	21.9419	2331	23.4703	2390	21.261673	2136	16.288319	1848	21.62143	2476	0.987184036	-0.034854061	normal	0.867114464	-0.356150648	normal	0.98817235	0.042682719	normal	0.636991793	-0.108010469	normal	--	--	--	K17589|0|pps:100974589|RB1CC1; RB1-inducible coiled-coil 1; K17589 RB1-inducible coiled-coil protein 1 (A)	--	[KRT]	Transcription;; General function prediction only;; Signal transduction mechanisms	Autophagy-related protein 11	RB1-inducible coiled-coil protein 1 GN=RB1CC1 OS=Homo sapiens (Human) PE=1 SV=3	KT	Transcription;; Signal transduction mechanisms	PREDICTED: RB1-inducible coiled-coil protein 1 isoform X1 [Equus caballus] 
ENSG00000023318(ERP44)	--	23.303793	844	24.3263731	830	27.530871	934	30.646422	1117	29.4183292	1027	31.040356	1079	0.789106632	0.372890329	normal	0.914363981	0.285358219	normal	0.958678793	0.199608032	normal	0.110700807	0.284337854	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: cell redox homeostasis (GO:0045454);; 	K17264|0|ptr:464616|ERP44; endoplasmic reticulum protein 44; K17264 endoplasmic reticulum resident protein 44 (A)	--	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Thioredoxin-like domain;; Thioredoxin;; Calsequestrin;; Hydrogenase-1 expression protein HyaE	Endoplasmic reticulum resident protein 44 (Precursor) GN=ERP44 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: endoplasmic reticulum protein 44 [Tupaia chinensis]
ENSG00000023330(ALAS1)	--	38.933444	1613	36.00467645	1526	40.77499448	1730	31.650924	1314	29.350841	1179	26.89138271	1134	0.88640866	-0.326268372	normal	0.762657443	-0.393173154	normal	0.040511732	-0.616971607	normal	0.003104901	-0.446318604	normal	[H]	Coenzyme transport and metabolism	Molecular Function: 5-aminolevulinate synthase activity (GO:0003870);; Cellular Component: mitochondrial matrix (GO:0005759);; Biological Process: porphyrin-containing compound metabolic process (GO:0006778);; Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00643|0|ptr:460416|ALAS1; aminolevulinate, delta-, synthase 1; K00643 5-aminolevulinate synthase [EC:2.3.1.37] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Porphyrin and chlorophyll metabolism (ko00860)"	[H]	Coenzyme transport and metabolism	Aminotransferase class I and II;; 5-aminolevulinate synthase presequence;; Cys/Met metabolism PLP-dependent enzyme;; Aminotransferase class-V	"5-aminolevulinate synthase, nonspecific, mitochondrial (Precursor) GN=ALAS1 OS=Homo sapiens (Human) PE=1 SV=2"	H	Coenzyme transport and metabolism	"PREDICTED: 5-aminolevulinate synthase, nonspecific, mitochondrial [Panthera tigris altaica]"
ENSG00000023445(BIRC3)	--	12.39587114	1074	13.97573303	1248	16.00935857	1362	16.70525177	1540	12.071282	1097	27.342506	2320	0.380828319	0.488517696	normal	0.959202884	-0.207212924	normal	0.000953083	0.759453072	normal	0.51194448	0.408463829	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K16060|0|hsa:330|BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2; baculoviral IAP repeat containing 3; K16060 baculoviral IAP repeat-containing protein 2/3 (A)"	NF-kappa B signaling pathway (ko04064);; Ubiquitin mediated proteolysis (ko04120);; Apoptosis (ko04210);; Focal adhesion (ko04510);; NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Small cell lung cancer (ko05222)	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	"Inhibitor of Apoptosis domain;; Caspase recruitment domain;; Zinc finger, C3HC4 type (RING finger)"	Baculoviral IAP repeat-containing protein 3 GN=BIRC3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: baculoviral IAP repeat-containing protein 3 [Galeopterus variegatus]
ENSG00000023516(AKAP11)	--	10.233904	1645	11.03988	1758	11.13269	1740	9.929639	1599	9.78106	1572	11.095	1785	0.98328238	-0.071681996	normal	0.971665628	-0.182594198	normal	0.985469169	0.028520852	normal	0.755629873	-0.07428434	normal	--	--	--	"K16527|0|hsa:11215|AKAP11, AKAP-11, AKAP220, PPP1R44, PRKA11; A kinase (PRKA) anchor protein 11; K16527 A-kinase anchor protein 11 (A)"	--	--	--	--	A-kinase anchor protein 11 GN=AKAP11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 11 isoform X2 [Galeopterus variegatus]
ENSG00000023572(GLRX2)	--	33.70494053	330	36.14278019	375	40.32983018	365	43.51461017	406	34.76855011	329	38.28068025	371	0.917266125	0.267058881	normal	0.942134541	-0.209327548	normal	0.969046902	0.015168942	normal	0.954684329	0.026221805	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Biological Process: cell redox homeostasis (GO:0045454);; 	K03676|1.06796e-120|ptr:745318|GLRX2; glutaredoxin 2; K03676 glutaredoxin 3 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Glutaredoxin	"Glutaredoxin-2, mitochondrial (Precursor) GN=GLRX2 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: glutaredoxin-2, mitochondrial [Echinops telfairi]"
ENSG00000023608(SNAPC1)	--	15.465616	657	15.86710617	672	15.650132	653	13.63950554	594	13.90440709	592	13.283914	568	0.95720023	-0.175830002	normal	0.949137963	-0.203801573	normal	0.947391022	-0.208964162	normal	0.378310302	-0.19765522	normal	--	--	--	"K15208|0|nle:100590192|SNAPC1; small nuclear RNA activating complex, polypeptide 1, 43kDa; K15208 snRNA-activating protein complex subunit 1 (A)"	--	[A]	RNA processing and modification	"Small nuclear RNA activating complex (SNAPc), subunit SNAP43"	snRNA-activating protein complex subunit 1 GN=SNAPC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: snRNA-activating protein complex subunit 1 [Ceratotherium simum simum]
ENSG00000023697(DERA)	--	32.72343004	758	30.12482088	703	29.25034647	710	30.92683953	752	28.38793704	672	32.20830285	748	0.975537704	-0.042211548	normal	0.971353246	-0.086300109	normal	0.974065051	0.066789192	normal	0.955958996	-0.020625438	normal	[F]	Nucleotide transport and metabolism	Molecular Function: lyase activity (GO:0016829);; 	K01619|0|ptr:465316|DERA; deoxyribose-phosphate aldolase (putative); K01619 deoxyribose-phosphate aldolase [EC:4.1.2.4] (A)	Pentose phosphate pathway (ko00030)	[F]	Nucleotide transport and metabolism	DeoC/LacD family aldolase	Deoxyribose-phosphate aldolase GN=DERA OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: putative deoxyribose-phosphate aldolase [Pteropus alecto]
ENSG00000023734(STRAP)	--	112.1814546	3391	115.8202667	3555	124.205011	3764	129.5245791	3986	122.318744	3661	121.731754	3680	0.980778826	0.202314047	normal	0.991170963	0.020952873	normal	0.991414018	-0.04083571	normal	0.815307238	0.059488666	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K13137|0|ptr:465315|STRAP; serine/threonine kinase receptor associated protein; K13137 serine-threonine kinase receptor-associated protein (A)	RNA transport (ko03013)	[I]	Lipid transport and metabolism	"WD domain, G-beta repeat"	Serine-threonine kinase receptor-associated protein GN=STRAP OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: serine-threonine kinase receptor-associated protein [Galeopterus variegatus]
ENSG00000023839(ABCC2)	--	70.630524	7503	94.5614	9932	78.70749	8173	83.729525	8808	77.015332	8095	116.83823	12308	0.989712121	0.200476728	normal	0.967806849	-0.316426265	normal	0.172911158	0.582278873	normal	0.706388162	0.169530824	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05666|0|hsa:1244|ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP; ATP-binding cassette, sub-family C (CFTR/MRP), member 2; K05666 ATP-binding cassette, subfamily C (CFTR/MRP), member 2 (A)"	ABC transporters (ko02010);; Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"ABC transporter transmembrane region;; ABC transporter;; RecF/RecN/SMC N terminal domain;; AAA ATPase domain;; 50S ribosome-binding GTPase;; Protein of unknown function, DUF258;; Miro-like protein"	Canalicular multispecific organic anion transporter 1 GN=ABCC2 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: canalicular multispecific organic anion transporter 1 [Physeter catodon]
ENSG00000023892(DEF6)	--	0.021629175	1	0.058822377	3	0	0	0.021463598	1	0.99464003	4	0.021422944	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PH domain	Differentially expressed in FDCP 6 homolog GN=DEF6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: differentially expressed in FDCP 6 homolog [Myotis lucifugus]
ENSG00000023902(PLEKHO1)	--	2.291177353	107	1.685557812	80	1.798951678	84	4.265981	200	4.235221906	196	2.429032498	115	0.02172229	0.86236448	normal	3.33E-05	1.255707161	up	0.8828438	0.438114147	normal	0.028993274	0.892307432	normal	--	--	--	--	--	--	--	PH domain	Pleckstrin homology domain-containing family O member 1 GN=PLEKHO1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family O member 1 [Chrysochloris asiatica]
ENSG00000023909(GCLM)	--	60.45563932	4064	79.88328139	5235	68.7464509	4482	55.34058722	3851	64.03026131	4319	63.41564688	4222	0.989953865	-0.108457412	normal	0.958700586	-0.298823572	normal	0.991164585	-0.094474663	normal	0.371558784	-0.174266412	normal	[R]	General function prediction only	--	"K11205|0|pale:102893851|GCLM; glutamate-cysteine ligase, modifier subunit; K11205 glutamate--cysteine ligase regulatory subunit (A)"	Glutathione metabolism (ko00480)	[E]	Amino acid transport and metabolism	Aldo/keto reductase family	Glutamate--cysteine ligase regulatory subunit GN=GCLM OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: glutamate--cysteine ligase regulatory subunit [Odobenus rosmarus divergens]
ENSG00000024048(UBR2)	--	4.992446	699	4.896002	706	4.947673226	684	5.5279024	791	5.138337	717	6.219738973	862	0.965479302	0.147248596	normal	0.975028119	0.000876515	normal	0.868025391	0.324759145	normal	0.478506896	0.161045954	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein catabolic process (GO:0030163);; 	K10626|0|nle:100605221|UBR2; ubiquitin protein ligase E3 component n-recognin 2; K10626 E3 ubiquitin-protein ligase UBR2 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATP-dependent Clp protease adaptor protein ClpS;; Putative zinc finger in N-recognin (UBR box)	E3 ubiquitin-protein ligase UBR2 GN=UBR2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase UBR2 isoformX1 [Canis lupus familiaris]
ENSG00000024422(EHD2)	--	90.50784518	5879	89.21118465	5774	92.48257858	6083	84.46125642	5443	72.8674973	4717	69.341334	4507	0.990961978	-0.141962433	normal	0.954223163	-0.313037178	normal	0.732516613	-0.440779194	normal	0.084138257	-0.295821433	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; 	"K12469|0|hsa:30846|EHD2, PAST2; EH-domain containing 2; K12469 EH domain-containing protein 2 (A)"	Endocytosis (ko04144)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Dynamin family;; Cytoskeletal-regulatory complex EF hand;; 50S ribosome-binding GTPase;; Miro-like protein	EH domain-containing protein 2 GN=EHD2 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: EH domain-containing protein 2 [Galeopterus variegatus]
ENSG00000024526(DEPDC1)	--	14.178676	1039	13.17121589	954	13.193748	981	12.0318615	902	11.76325891	866	11.15846452	808	0.945187816	-0.234456076	normal	0.9657118	-0.16078116	normal	0.910470981	-0.287699787	normal	0.231098047	-0.228794764	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	"Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; RhoGAP domain"	DEP domain-containing protein 1A GN=DEPDC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DEP domain-containing protein 1A isoform X6 [Physeter catodon]
ENSG00000024862(CCDC28A)	--	7.6547686	157	7.425855961	152	7.448226373	151	8.126438123	172	8.34798866	168	8.143610431	171	0.964062123	0.09987775	normal	0.961061786	0.121810271	normal	0.956819842	0.16955965	normal	0.77952704	0.13044269	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4061)	Coiled-coil domain-containing protein 28A GN=CCDC28A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 28A [Galeopterus variegatus]
ENSG00000025039(RRAGD)	--	4.41458135	346	5.670951215	444	4.563252278	353	6.885253062	542	5.561571067	434	11.2781934	884	0.094990265	0.614491912	normal	0.968434675	-0.054104791	normal	4.87E-11	1.312410014	up	0.25543502	0.682502168	normal	--	--	Molecular Function: GTP binding (GO:0005525);; 	K16186|0|ptr:462884|RRAGD; Ras-related GTP binding D; K16186 Ras-related GTP-binding protein C/D (A)	mTOR signaling pathway (ko04150)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Gtr1/RagA G protein conserved region;; ADP-ribosylation factor family;; Miro-like protein;; Signal recognition particle receptor beta subunit	Ras-related GTP-binding protein D OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related GTP-binding protein D [Galeopterus variegatus]
ENSG00000025156(HSF2)	--	6.410680005	279	5.35947313	232	4.814363947	206	4.058139609	179	5.181210347	226	4.971376035	218	0.124044477	-0.666514644	normal	0.964512045	-0.058839968	normal	0.964932904	0.072872264	normal	0.508742812	-0.223615268	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09415|0|ptr:462974|HSF2; heat shock transcription factor 2; K09415 heat shock transcription factor 2 (A)	--	[K]	Transcription	Vertebrate heat shock transcription factor;; HSF-type DNA-binding	Heat shock factor protein 2 GN=HSF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: heat shock factor protein 2 isoform X1 [Eptesicus fuscus]
ENSG00000025293(PHF20)	--	9.390045641	1095	8.6796563	1037	8.7581583	1036	9.1592722	1149	7.699421028	937	8.680426578	1049	0.980337658	0.038562842	normal	0.965743821	-0.167464441	normal	0.980060535	0.009685183	normal	0.900535826	-0.036700372	normal	[R]	General function prediction only	--	"K18402|0|hsa:51230|PHF20, C20orf104, GLEA2, HCA58, NZF, TDRD20A, TZP; PHD finger protein 20; K18402 PHD finger protein 20 (A)"	--	[R]	General function prediction only	Protein of unknown function (DUF3776);; PHD-finger	PHD finger protein 20 GN=PHF20 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: PHD finger protein 20 [Lipotes vexillifer]
ENSG00000025423(HSD17B6)	--	0.600514708	10	0.259150107	8	0.368695	10	0.823187603	23	2.52200893	55	1.20713989	31	0.92698684	1.060912518	normal	7.09E-06	2.551264329	up	0.42802837	1.490256525	normal	0.019350593	1.940937511	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K13369|0|hsa:8630|HSD17B6, HSE, RODH, SDR9C6; hydroxysteroid (17-beta) dehydrogenase 6 (EC:1.1.1.62 1.1.1.239 1.1.1.105); K13369 17beta-estradiol 17-dehydrogenase / all-trans-retinol dehydrogenase (NAD+) / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.105 1.1.1.239] (A)"	Steroid hormone biosynthesis (ko00140);; Retinol metabolism (ko00830)	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	short chain dehydrogenase	17-beta-hydroxysteroid dehydrogenase type 6 (Precursor) GN=HSD17B6 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 17-beta-hydroxysteroid dehydrogenase type 6 [Orycteropus afer afer]
ENSG00000025434(NR1H3)	--	9.650015864	297	8.478620432	232	9.235451026	284	8.669330714	265	10.7440134	317	9.468146097	288	0.947549564	-0.194238291	normal	0.737890276	0.426544247	normal	0.967601218	0.011823917	normal	0.845389714	0.077066413	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08536|3.90745e-167|pps:100971327|NR1H3; nuclear receptor subfamily 1, group H, member 3; K08536 liver X receptor alpha (A)"	PPAR signaling pathway (ko03320);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Oxysterols receptor LXR-alpha GN=NR1H3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	MAP kinase-activating death domain protein isoform 3 [Camelus ferus]
ENSG00000025708(TYMP)	--	19.97164301	322	19.0968319	333	19.99368622	338	30.40717155	632	37.79680471	790	26.42580376	529	4.88E-05	0.938777637	normal	4.74E-09	1.221194879	up	0.068171843	0.635661218	normal	0.000264071	0.952889741	normal	[F]	Nucleotide transport and metabolism	"Biological Process: pyrimidine nucleoside metabolic process (GO:0006213);; Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; Molecular Function: transferase activity, transferring pentosyl groups (GO:0016763);; "	"K00758|0|hsa:1890|TYMP, ECGF, ECGF1, MEDPS1, MNGIE, MTDPS1, PDECGF, TP, hPD-ECGF; thymidine phosphorylase (EC:2.4.2.4); K00758 thymidine phosphorylase [EC:2.4.2.4] (A)"	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983);; Bladder cancer (ko05219)	--	--	"Glycosyl transferase family, a/b domain;; Glycosyl transferase family, helical bundle domain;; Pyrimidine nucleoside phosphorylase C-terminal domain"	Thymidine phosphorylase (Precursor) GN=TYMP OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: thymidine phosphorylase [Ceratotherium simum simum]
ENSG00000025770(NCAPH2)	--	11.07478025	465	12.81213901	557	12.91365691	557	13.419046	537	11.19701582	450	11.42322277	469	0.954419302	0.176316668	normal	0.862890908	-0.328185437	normal	0.924373947	-0.255623513	normal	0.606241439	-0.1385482	normal	--	--	--	"K11490|0|hsa:29781|NCAPH2, CAPH2; non-SMC condensin II complex, subunit H2; K11490 condensin-2 complex subunit H2 (A)"	--	--	--	Protein of unknown function (DUF1032)	Condensin-2 complex subunit H2 GN=NCAPH2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: condensin-2 complex subunit H2 isoform X1 [Galeopterus variegatus]
ENSG00000025772(TOMM34)	--	17.99802	756	19.13744	798	20.18618	847	24.42996	1023	22.8116	945	22.23278	929	0.702916983	0.404806206	normal	0.948193894	0.222111851	normal	0.97139158	0.124812334	normal	0.18416393	0.249571788	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K17766|0|ggo:101127514|TOMM34; mitochondrial import receptor subunit TOM34; K17766 mitochondrial import receptor subunit TOM34 (A)	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Fis1 C-terminal tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Mitochondrial import receptor subunit TOM34 GN=TOMM34 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import receptor subunit TOM34 [Ochotona princeps]
ENSG00000025796(SEC63)	--	13.31682461	1463	15.96249443	1415	15.7674597	1506	13.70065033	1519	13.67915161	1496	14.28056697	1562	0.983813052	0.023335786	normal	0.982238048	0.058820423	normal	0.983709178	0.044337523	normal	0.882851418	0.041130472	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K09540|0|hgl:101701880|Sec63; SEC63 homolog (S. cerevisiae); K09540 translocation protein SEC63 (A)	Protein export (ko03060);; Protein processing in endoplasmic reticulum (ko04141)	[UO]	"Intracellular trafficking, secretion, and vesicular transport;; Posttranslational modification, protein turnover, chaperones"	Sec63 Brl domain;; DnaJ domain	Translocation protein SEC63 homolog GN=SEC63 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	SEC63-like protein (predicted) [Dasypus novemcinctus]
ENSG00000025800(KPNA6)	--	13.9846934	1858	15.31611712	2036	14.78488973	1942	15.16076897	2008	15.07553216	1982	14.58960095	1935	0.984708425	0.081111977	normal	0.985619941	-0.060161863	normal	0.986553227	-0.013490552	normal	1	0.000516601	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein import into nucleus (GO:0006606);; Molecular Function: protein transporter activity (GO:0008565);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Armadillo/beta-catenin-like repeat;; HEAT repeats;; Importin beta binding domain;; HEAT-like repeat;; HEAT repeat;; Armadillo-like;; V-ATPase subunit H	Importin subunit alpha-7 GN=KPNA6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin subunit alpha-7 isoform X1 [Condylura cristata] 
ENSG00000026025(VIM)	--	847.9228003	24497	879.8020187	23624	883.7094025	24729	1448.186017	41103	1106.499253	33271	972.1859	28576	0.013078668	0.715771338	normal	0.856126712	0.472559805	normal	0.996095948	0.200297239	normal	0.031650931	0.476676606	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	K07606|0|pps:100992862|VIM; vimentin; K07606 vimentin (A)	Epstein-Barr virus infection (ko05169);; MicroRNAs in cancer (ko05206)	--	--	Intermediate filament protein;; Intermediate filament head (DNA binding) region	Vimentin GN=VIM OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	vimentin [Canis lupus familiaris] 
ENSG00000026103(FAS)	--	8.83252475	392	12.2766	545	11.26571857	494	14.6004694	654	11.11988548	490	18.27559501	817	0.012891432	0.705442747	normal	0.954711995	-0.1743904	normal	0.007229776	0.71581211	normal	0.279117579	0.433984541	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K04390|0|hsa:355|FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6; Fas cell surface death receptor; K04390 tumor necrosis factor receptor superfamily member 6 (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; p53 signaling pathway (ko04115);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; TNF signaling pathway (ko04668);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Type I diabetes mellitus (ko04940);; Alzheimer's disease (ko05010);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Autoimmune thyroid disease (ko05320);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332)	--	--	Death domain;; TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 6 (Precursor) GN=FAS OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 6 [Galeopterus variegatus]
ENSG00000026297(RNASET2)	--	15.60444676	332	12.93038601	279	12.39513136	271	17.4090717	373	16.79458171	354	16.65452524	359	0.95951275	0.136563673	normal	0.88024001	0.320512224	normal	0.779711389	0.395476104	normal	0.287288683	0.278682141	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: ribonuclease T2 activity (GO:0033897);; 	K01166|1.42965e-148|nle:100595076|RNASET2; ribonuclease T2; K01166 ribonuclease T2 [EC:3.1.27.1] (A)	--	[A]	RNA processing and modification	Ribonuclease T2 family	Ribonuclease T2 (Precursor) GN=RNASET2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribonuclease T2 [Oryctolagus cuniculus]
ENSG00000026508(CD44)	--	162.5775831	11128	136.7140788	9440	167.8233104	11281	246.1217003	15849	192.6007021	13357	186.5847343	12010	0.721114005	0.479309521	normal	0.717405933	0.479245851	normal	0.996178259	0.082039088	normal	0.065137782	0.350098495	normal	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	"K06256|0|hsa:960|CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1; CD44 molecule (Indian blood group); K06256 CD44 antigen (A)"	ECM-receptor interaction (ko04512);; Hematopoietic cell lineage (ko04640);; Shigellosis (ko05131);; Epstein-Barr virus infection (ko05169);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	--	--	Extracellular link domain	CD44 antigen (Precursor) GN=CD44 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: CD44 antigen isoform X1 [Lipotes vexillifer]
ENSG00000026559(KCNG1)	--	7.066440601	254	4.8682451	163	5.4733226	196	2.960082563	85	4.92306609	162	1.94676927	69	9.25E-10	-1.59261481	down	0.965943606	-0.030025283	normal	2.25E-07	-1.494166593	down	0.041611356	-0.977225598	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04900|0|ptr:745113|KCNG1; potassium voltage-gated channel, subfamily G, member 1; K04900 potassium voltage-gated channel subfamily G member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily G member 1 GN=KCNG1 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily G member 1 [Camelus ferus] 
ENSG00000026652(AGPAT4)	--	3.240755099	239	2.619902054	222	3.359999802	228	2.756580301	228	2.400656317	226	3.19065651	245	0.963033252	-0.098162858	normal	0.965864727	0.004307457	normal	0.963356325	0.094849473	normal	1	-0.000199548	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13523|0|hsa:56895|AGPAT4, 1-AGPAT4, LPAAT-delta, dJ473J16.2; 1-acylglycerol-3-phosphate O-acyltransferase 4 (EC:2.3.1.51); K13523 lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	1-acyl-sn-glycerol-3-phosphate acyltransferase delta GN=AGPAT4 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase delta [Equus caballus] 
ENSG00000026751(SLAMF7)	--	0.174193376	10	0.885837651	16	0.179460032	9	2.332067291	112	1.800476405	94	2.910849946	144	3.11E-15	3.270311843	up	4.86E-09	2.426987115	up	0	3.783340466	up	7.08E-15	3.300715061	up	--	--	--	K06733|0|pps:100989780|SLAMF7; SLAM family member 7; K06733 SLAM family member 7 (A)	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain	SLAM family member 7 (Precursor) GN=SLAMF7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SLAM family member 7 isoform X1 [Equus przewalskii]
ENSG00000026950(BTN3A1)	--	6.6154928	504	4.406158767	336	7.801061139	489	7.334533296	527	8.215223651	561	8.1969104	600	0.971545245	0.033447252	normal	0.015831235	0.715594827	normal	0.904061587	0.286036694	normal	0.172227103	0.324541771	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06712|0|pps:100976134|BTN3A1; butyrophilin, subfamily 3, member A1; K06712 butyrophilin (A)"	--	--	--	SPRY domain;; SPRY-associated domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; CD80-like C2-set immunoglobulin domain	Butyrophilin subfamily 3 member A1 (Precursor) GN=BTN3A1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: butyrophilin subfamily 3 member A3-like isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000027001(MIPEP)	--	10.27555463	421	9.528451	376	10.60928527	432	11.21591018	463	10.788698	433	9.8388128	401	0.965166752	0.105990773	normal	0.950668683	0.181527016	normal	0.963714042	-0.115301465	normal	0.875136822	0.056241302	normal	[E]	Amino acid transport and metabolism	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K01410|0|hsa:4285|MIPEP, HMIP, MIP; mitochondrial intermediate peptidase (EC:3.4.24.59); K01410 mitochondrial intermediate peptidase [EC:3.4.24.59] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M3	Mitochondrial intermediate peptidase (Precursor) GN=MIPEP OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial intermediate peptidase [Tupaia chinensis]
ENSG00000027075(PRKCH)	--	15.43939634	768	12.9413453	786	26.09459514	839	4.780921573	293	6.416336003	403	8.825989	477	1.87E-12	-1.416264458	down	8.73E-06	-0.982484837	normal	0.000505326	-0.820983818	normal	5.56E-11	-1.048207514	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K18051|0|hsa:5583|PRKCH, PKC-L, PKCL, PRKCL, nPKC-eta; protein kinase C, eta (EC:2.7.11.13); K18051 novel protein kinase C eta type [EC:2.7.11.13] (A)"	Vascular smooth muscle contraction (ko04270);; Tight junction (ko04530);; Inflammatory mediator regulation of TRP channels (ko04750)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2 domain;; Protein kinase C terminal domain;; Kinase-like	Protein kinase C eta type GN=PRKCH OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: protein kinase C eta type [Tupaia chinensis]
ENSG00000027697(IFNGR1)	--	28.977073	1049	23.111596	842	23.78225664	847	27.591152	1004	46.59472	1689	43.238407	1564	0.976378291	-0.093947	normal	1.66E-06	0.981581743	normal	3.86E-05	0.875347326	normal	0.104454917	0.616731807	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: membrane (GO:0016020);; Molecular Function: cytokine binding (GO:0019955);; 	"K05132|0|hsa:3459|IFNGR1, CD119, IFNGR, IMD27A, IMD27B; interferon gamma receptor 1; K05132 interferon gamma receptor 1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; Osteoclast differentiation (ko04380);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; Salmonella infection (ko05132);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Inflammatory bowel disease (IBD) (ko05321)	--	--	"Interferon gamma receptor (IFNGR1);; Tissue factor;; Interferon-alpha/beta receptor, fibronectin type III"	Interferon gamma receptor 1 (Precursor) GN=IFNGR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interferon gamma receptor 1 [Tupaia chinensis]
ENSG00000027847(B4GALT7)	--	14.6521638	700	13.0929228	589	15.23460801	705	14.33791087	663	17.68193856	777	15.2259314	720	0.969637398	-0.108932586	normal	0.781368331	0.377374417	normal	0.975492181	0.022035434	normal	0.723241561	0.094680261	normal	--	--	--	"K00733|0|ptr:664711|B4GALT7, b4Gal-T7; xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (galactosyltransferase I) (EC:2.4.1.133); K00733 xylosylprotein 4-beta-galactosyltransferase [EC:2.4.1.133] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532);; Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[G]	Carbohydrate transport and metabolism	N-terminal domain of galactosyltransferase;; N-terminal region of glycosyl transferase group 7;; Glycosyltransferase like family 2	Xylosylprotein 4-beta-galactosyltransferase GN=B4GALT7 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-galactosyltransferase 7 isoform X1 [Pteropus alecto] "
ENSG00000027869(SH2D2A)	--	0.295071284	9	0.456841866	14	0.282484098	8	0.750501032	23	1.050063319	32	0.160239601	5	0.892507155	1.191917789	normal	0.798924144	1.091380185	normal	--	--	--	--	--	--	--	--	--	"K08273|0|hsa:9047|SH2D2A, F2771, SCAP, TSAD, VRAP; SH2 domain containing 2A; K08273 SH2 domain protein 2A (A)"	VEGF signaling pathway (ko04370)	--	--	SH2 domain	SH2 domain-containing protein 2A GN=SH2D2A OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SH2 domain-containing protein 2A isoform X1 [Loxodonta africana]
ENSG00000028116(VRK2)	--	11.08003261	672	11.75073	626	10.86583702	588	11.17952167	765	11.6669174	774	7.583327	494	0.9634143	0.155832168	normal	0.909115472	0.284126081	normal	0.922905721	-0.258869205	normal	0.840739223	0.085821473	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08816|0|hsa:7444|VRK2; vaccinia related kinase 2 (EC:2.7.11.1); K08816 vaccinia related kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase VRK2 GN=VRK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase VRK2 isoform X2 [Physeter catodon]
ENSG00000028137(TNFRSF1B)	--	0.267692038	21	0.0376778	3	0.0492184	3	0.300059	14	0.260109	20	0.316164	13	0.98109603	-0.564859695	normal	0.279237468	2.236150692	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05141|0|hsa:7133|TNFRSF1B, CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR; tumor necrosis factor receptor superfamily, member 1B; K05141 tumor necrosis factor receptor superfamily member 1B (A)"	Cytokine-cytokine receptor interaction (ko04060);; TNF signaling pathway (ko04668);; Adipocytokine signaling pathway (ko04920);; Amyotrophic lateral sclerosis (ALS) (ko05014)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor-binding protein 2 (Precursor) GN=TNFRSF1B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 1B isoform 1 [Orcinus orca]
ENSG00000028203(VEZT)	--	37.30442687	2177	34.80009847	1974	36.02504539	2124	52.23350187	2898	50.07630737	2710	42.976187	2532	0.82554522	0.381649795	normal	0.673027692	0.435458506	normal	0.961724348	0.245042209	normal	0.023193391	0.353877499	normal	--	--	Molecular Function: myosin binding (GO:0017022);; 	--	--	--	--	Mysoin-binding motif of peroxisomes	Vezatin GN=VEZT OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: vezatin isoform X3 [Galeopterus variegatus]
ENSG00000028277(POU2F2)	--	0.223972547	33	0.140711567	24	0.246484631	19	0.257446558	19	0.1376929	11	0.162675237	16	0.929296142	-0.77892553	normal	0.911086353	-1.047343667	normal	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09364|0|cfa:484478|POU2F2; POU class 2 homeobox 2; K09364 POU domain transcription factor, class 2 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 2, transcription factor 2 GN=POU2F2 OS=Homo sapiens (Human) PE=1 SV=3"	K	Transcription	"PREDICTED: POU domain, class 2, transcription factor 2 isoform X4 [Canis lupus familiaris] "
ENSG00000028310(BRD9)	--	9.771411	500	8.462794639	454	9.352697595	502	9.64205774	512	11.784016	613	9.457207	502	0.971847413	0.003373209	normal	0.707652136	0.410587259	normal	0.971852009	-0.008266539	normal	0.60106109	0.139172344	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	K11723|0|ptr:750795|BRD9; bromodomain containing 9; K11723 bromodomain-containing protein 7/9 (A)	--	[K]	Transcription	Domain of unknown function (DUF3512);; Bromodomain	Bromodomain-containing protein 9 GN=BRD9 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: bromodomain-containing protein 9 [Eptesicus fuscus]
ENSG00000028528(SNX1)	--	42.94835617	2084	40.46418305	2005	44.46415388	1986	41.5385928	2048	46.7703603	2280	41.58307559	2007	0.986362513	-0.055930229	normal	0.978572947	0.16388905	normal	0.986860329	0.006878342	normal	0.886398301	0.039232317	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K17917|0|hsa:6642|SNX1, HsT17379, VPS5; sorting nexin 1; K17917 sorting nexin-1/2 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Vps5 C terminal like;; Sorting nexin, N-terminal domain;; PX domain"	Sorting nexin-1 GN=SNX1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-1 isoform X2 [Felis catus]
ENSG00000028839(TBPL1)	--	12.285828	249	13.30389126	245	13.16352442	222	15.80497982	299	14.94817477	283	12.83569712	253	0.936227783	0.231860523	normal	0.948787437	0.185527507	normal	0.951831167	0.179142405	normal	0.535261691	0.199955559	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K03120|5.43876e-135|pon:100173239|TBPL1; TBP-like 1; K03120 transcription initiation factor TFIID TATA-box-binding protein (A)	Basal transcription factors (ko03022);; Huntington's disease (ko05016);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	"Transcription factor TFIID (or TATA-binding protein, TBP)"	TATA box-binding protein-like protein 1 GN=TBPL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: TATA box-binding protein-like protein 1 [Bubalus bubalis]
ENSG00000029153(ARNTL2)	--	16.39593232	1436	16.84357517	1306	18.34467776	1518	28.0624028	2763	21.28660107	1819	19.59865288	1665	6.67E-06	0.912631823	normal	0.554731342	0.456114705	normal	0.979357667	0.124940059	normal	0.179658141	0.529623446	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09099|0|hsa:56938|ARNTL2, BMAL2, CLIF, MOP9, PASD9, bHLHe6; aryl hydrocarbon receptor nuclear translocator-like 2; K09099 aryl hydrocarbon receptor nuclear translocator-like protein 2 (A)"	--	[K]	Transcription	PAS domain;; PAS fold;; PAS fold;; Helix-loop-helix DNA-binding domain;; PAS domain;; PAS fold	Aryl hydrocarbon receptor nuclear translocator-like protein 2 GN=ARNTL2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: aryl hydrocarbon receptor nuclear translocator-like protein 2 [Orcinus orca]
ENSG00000029363(BCLAF1)	--	35.689176	3189	41.78207726	3735	40.902713	3628	40.84937278	3782	40.02232305	3582	37.92901316	3519	0.977699258	0.215117746	normal	0.990116299	-0.081735666	normal	0.990947346	-0.052278256	normal	0.939370018	0.023196208	normal	--	--	--	K13087|0|ggo:101142513|BCLAF1; bcl-2-associated transcription factor 1; K13087 bcl2 associated transcription factor 1 (A)	--	--	--	THRAP3/BCLAF1 family	Bcl-2-associated transcription factor 1 GN=BCLAF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: bcl-2-associated transcription factor 1 isoform X2 [Sus scrofa]
ENSG00000029364(SLC39A9)	--	27.99792701	2313	28.90381727	2391	26.89590091	2189	28.99024734	2394	30.72146934	2534	30.12401586	2502	0.988232535	0.018813339	normal	0.987467803	0.062337535	normal	0.977058099	0.184399153	normal	0.705814122	0.087062067	normal	--	--	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14715|1.91767e-179|ptr:452998|SLC39A9; solute carrier family 39, member 9; K14715 solute carrier family 39 (zinc transporter), member 9 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ZIP Zinc transporter	Zinc transporter ZIP9 GN=SLC39A9 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP9 isoform 1 [Trichechus manatus latirostris]
ENSG00000029534(ANK1)	--	1.186802811	236	1.494250592	300	2.254023284	343	3.44160945	656	3.205580028	640	3.761113869	748	4.27E-12	1.438225318	up	1.69E-06	1.067912526	up	1.36E-07	1.113131809	up	1.58E-12	1.197055111	up	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K10380|0|pps:100993640|ANK1; ankyrin 1, erythrocytic; K10380 ankyrin (A)"	Proteoglycans in cancer (ko05205)	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; ZU5 domain;; Death domain	Ankyrin-1 GN=ANK1 OS=Homo sapiens (Human) PE=1 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: ankyrin-1 isoform X1 [Eptesicus fuscus]
ENSG00000029559(IBSP)	--	0	0	0	0	0	0	0	0	0	0	0.0260092	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: ossification (GO:0001503);; Cellular Component: extracellular region (GO:0005576);; Biological Process: cell adhesion (GO:0007155);; 	"K06253|1.26091e-110|hsa:3381|IBSP, BNSP, BSP, BSP-II, SP-II; integrin-binding sialoprotein; K06253 integrin binding sialoprotein (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512)	[S]	Function unknown	Bone sialoprotein II (BSP-II)	Bone sialoprotein 2 (Precursor) GN=IBSP OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: bone sialoprotein 2 [Physeter catodon]
ENSG00000029639(TFB1M)	--	6.24414	152	5.58841	136	5.49575	133	6.22967	153	6.9998	169	5.92357	145	0.96769011	-0.021158763	normal	0.926949597	0.28910144	normal	0.964137457	0.115081655	normal	0.792026961	0.128208316	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K15266|0|hsa:51106|TFB1M, CGI75, mtTFB, mtTFB1; transcription factor B1, mitochondrial (EC:2.1.1.-); K15266 dimethyladenosine transferase 1, mitochondrial [EC:2.1.1.-] (A)"	--	[A]	RNA processing and modification	Ribosomal RNA adenine dimethylase	"Dimethyladenosine transferase 1, mitochondrial (Precursor) GN=TFB1M OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: dimethyladenosine transferase 1, mitochondrial [Canis lupus familiaris]"
ENSG00000029725(RABEP1)	--	24.31682728	2370	27.09705334	2597	28.00439343	2518	25.86830304	2694	26.02868619	2597	25.555847	2457	0.982216276	0.153936885	normal	0.988718719	-0.021414088	normal	0.988342374	-0.04364533	normal	0.918339744	0.028366444	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: growth factor activity (GO:0008083);; 	K12480|0|ggo:101151428|RABEP1; rab GTPase-binding effector protein 1 isoform 1; K12480 Rab GTPase-binding effector protein 1 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rabaptin;; Rabaptin-like protein	Rab GTPase-binding effector protein 1 GN=RABEP1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab GTPase-binding effector protein 1 [Orcinus orca]
ENSG00000029993(HMGB3)	--	111.7106103	4713	100.370393	3814	95.67754	3927	83.96688546	3179	76.10947	3208	97.401838	3768	0.072376937	-0.598665595	normal	0.962473472	-0.270939952	normal	0.991109734	-0.067893381	normal	0.077906034	-0.315210571	normal	--	--	--	K11296|5.48048e-101|myb:102246717|HMGB3; high mobility group box 3; K11296 high mobility group protein B3 (A)	--	[R]	General function prediction only	HMG-box domain;; HMG (high mobility group) box;; HMG (high mobility group) box 5	High mobility group protein B3 GN=HMGB3 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: high mobility group protein B3 [Myotis brandtii]
ENSG00000030066(NUP160)	--	19.47113525	1761	19.84744334	1775	19.42675955	1736	16.65110736	1512	17.12094265	1535	15.341409	1360	0.95055365	-0.250532846	normal	0.959054885	-0.230795257	normal	0.836949535	-0.360096407	normal	0.094477098	-0.280054949	normal	--	--	--	K14303|0|hsa:23279|NUP160; nucleoporin 160kDa; K14303 nuclear pore complex protein Nup160 (A)	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Nucleoporin Nup120/160	Nuclear pore complex protein Nup160 GN=NUP160 OS=Homo sapiens (Human) PE=1 SV=3	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup160 [Camelus ferus]
ENSG00000030110(BAK1)	--	10.62248925	384	8.876606951	334	9.640920157	357	15.099958	553	16.05248714	574	12.2369215	448	0.431931683	0.49368688	normal	0.006403517	0.757131005	normal	0.876356051	0.318077978	normal	0.006574689	0.529308369	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K14021|5.45139e-131|hsa:578|BAK1, BAK, BAK-LIKE, BCL2L7, CDN1; BCL2-antagonist/killer 1; K14021 Bcl-2 homologous antagonist/killer (A)"	Protein processing in endoplasmic reticulum (ko04141);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	"Apoptosis regulator proteins, Bcl-2 family"	Bcl-2 homologous antagonist/killer GN=BAK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bcl-2 homologous antagonist/killer [Odobenus rosmarus divergens]
ENSG00000030304(MUSK)	--	0	0	0	0	0	0	0.04506635	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05129|0|pps:100982699|MUSK; muscle, skeletal, receptor tyrosine kinase; K05129 muscle, skeletal, receptor tyrosine kinase [EC:2.7.10.1] (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Protein tyrosine kinase;; Immunoglobulin I-set domain;; Protein kinase domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fz domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	"Muscle, skeletal receptor tyrosine-protein kinase (Precursor) GN=MUSK OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: muscle, skeletal receptor tyrosine-protein kinase isoform X4 [Tupaia chinensis]"
ENSG00000030419(IKZF2)	--	1.023208236	78	0.854908825	72	0.722992092	69	0.296037756	44	0.753003733	48	0.433753747	64	0.48353332	-0.834608325	normal	0.85592569	-0.591077757	normal	0.973370093	-0.114215987	normal	0.317733434	-0.509581901	normal	[R]	General function prediction only	--	K09220|0|pps:100968912|IKZF2; IKAROS family zinc finger 2 (Helios); K09220 IKAROS family zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein Helios GN=IKZF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein Helios-like isoform X1 [Tupaia chinensis]
ENSG00000030582(GRN)	--	164.8997873	6189	172.9715956	6762	147.6863274	5729	167.9838781	6052	193.9679382	7046	251.3399656	9375	0.993939327	-0.063110753	normal	0.99458238	0.037919593	normal	0.006901183	0.702097598	normal	0.506350471	0.246590341	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Granulin	Granulin-7 (Precursor) GN=GRN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: granulins [Ceratotherium simum simum]
ENSG00000031003(FAM13B)	--	7.82907022	711	9.679650972	903	7.555570207	624	9.155807619	868	6.84808405	646	9.979228895	823	0.929486732	0.256510894	normal	0.351972042	-0.503616155	normal	0.744205913	0.390228953	normal	0.93328451	0.040466189	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	RhoGAP domain	Protein FAM13B GN=FAM13B OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein FAM13B isoform X5 [Mustela putorius furo] 
ENSG00000031081(ARHGAP31)	--	1.77918702	187	0.517512046	104	0.840204766	128	2.653932546	299	2.885916608	338	3.309708921	288	0.157094231	0.642068603	normal	6.67E-12	1.664827463	up	1.28E-05	1.152314216	up	1.20E-06	1.121181872	up	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain	Rho GTPase-activating protein 31 GN=ARHGAP31 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 31 [Ceratotherium simum simum]
ENSG00000031691(CENPQ)	--	7.611766	209	9.283	258	10.88722	297	7.88958	226	7.31678	205	7.36075	205	0.964356361	0.081411967	normal	0.866456343	-0.350860898	normal	0.433652686	-0.539802771	normal	0.351079854	-0.285651894	normal	--	--	--	"K11509|3.57885e-175|hsa:55166|CENPQ, C6orf139, CENP-Q; centromere protein Q; K11509 centromere protein Q (A)"	--	--	--	"CENP-Q, a CENPA-CAD centromere complex subunit"	Centromere protein Q GN=CENPQ OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein Q [Ceratotherium simum simum]
ENSG00000031698(SARS)	--	42.401983	1549	40.382734	1513	41.477219	1537	40.076933	1487	39.08448	1408	50.78482	1847	0.981554251	-0.089673966	normal	0.977844975	-0.125061594	normal	0.948719796	0.256544692	normal	0.943643227	0.023617051	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	K01875|0|tup:102469557|SARS; seryl-tRNA synthetase; K01875 seryl-tRNA synthetase [EC:6.1.1.11] (A)	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetase class II core domain (G, H, P, S and T);; Seryl-tRNA synthetase N-terminal domain"	"Serine--tRNA ligase, cytoplasmic GN=SARS OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: serine--tRNA ligase, cytoplasmic isoform X1 [Tupaia chinensis]"
ENSG00000031823(RANBP3)	--	15.57992891	827	14.9002816	890	15.20922768	895	17.90080631	977	18.25150501	1000	15.58013134	894	0.953423727	0.209280945	normal	0.968740452	0.146461326	normal	0.978291268	-0.009887577	normal	0.623142848	0.115042224	normal	--	--	Biological Process: intracellular transport (GO:0046907);; 	K15304|0|hsa:8498|RANBP3; RAN binding protein 3; K15304 Ran-binding protein 3 (A)	HTLV-I infection (ko05166)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain	Ran-binding protein 3 GN=RANBP3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ran-binding protein 3 isoform X4 [Galeopterus variegatus]
ENSG00000032219(ARID4A)	--	4.576265521	566	3.890312375	503	4.782339413	569	4.776315916	604	4.182434678	496	4.841420825	607	0.971625498	0.062749334	normal	0.970277009	-0.04151913	normal	0.970284024	0.084758286	normal	0.909621777	0.038400766	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[BK]	Chromatin structure and dynamics;; Transcription	RBB1NT (NUC162) domain;; ARID/BRIGHT DNA binding domain;; RNA binding activity-knot of a chromodomain	AT-rich interactive domain-containing protein 4A GN=ARID4A OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 4A [Tupaia chinensis]
ENSG00000032389(TSSC1)	--	26.38268651	849	23.24515071	862	29.31819036	941	23.0947276	744	22.74167608	744	24.27097539	769	0.946954795	-0.220866814	normal	0.942010956	-0.233370639	normal	0.899209542	-0.298970116	normal	0.183621959	-0.253595649	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	Protein TSSC1 GN=TSSC1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein TSSC1 [Loxodonta africana]
ENSG00000032444(PNPLA6)	--	33.07400593	2352	29.88733304	1937	33.4985911	2306	21.89028161	1429	23.27777458	1601	28.10618336	1919	0.001232513	-0.749079569	normal	0.926801439	-0.296022551	normal	0.946504304	-0.273132596	normal	0.019872467	-0.434363794	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K14676|0|hsa:10908|PNPLA6, BNHS, NTE, NTEMND, SPG39, iPLA2delta, sws; patatin-like phospholipase domain containing 6 (EC:3.1.1.5); K14676 lysophospholipid hydrolase [EC:3.1.1.5] (A)"	Glycerophospholipid metabolism (ko00564)	[R]	General function prediction only	Cyclic nucleotide-binding domain;; Patatin-like phospholipase	Neuropathy target esterase GN=PNPLA6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: neuropathy target esterase isoform X1 [Vicugna pacos]
ENSG00000032742(IFT88)	--	7.40883509	359	6.349235505	292	7.404422254	366	5.94908881	308	7.561483586	340	5.060856655	246	0.926611728	-0.250725845	normal	0.945624349	0.197192665	normal	0.246796399	-0.578541389	normal	0.479300475	-0.207432797	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K16474|0|pps:100973420|IFT88; intraflagellar transport 88; K16474 intraflagellar transport protein 88 (A)	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Intraflagellar transport protein 88 homolog GN=IFT88 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: intraflagellar transport protein 88 homolog [Odobenus rosmarus divergens]
ENSG00000033011(ALG1)	--	18.086405	424	18.33745249	550	19.10554707	444	27.034751	608	20.59065954	559	27.384737	671	0.438834983	0.487692008	normal	0.972159741	0.001984694	normal	0.121295603	0.585827357	normal	0.076393168	0.353124707	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K03842|0|hsa:56052|ALG1, CDG1K, HMAT1, HMT-1, HMT1, MT-1, Mat-1, hMat-1; ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase (EC:2.4.1.142); K03842 beta-1,4-mannosyltransferase [EC:2.4.1.142] (A)"	N-Glycan biosynthesis (ko00510)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferases group 1;; Glycosyl transferases group 1	Chitobiosyldiphosphodolichol beta-mannosyltransferase GN=ALG1 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: chitobiosyldiphosphodolichol beta-mannosyltransferase isoform X1 [Galeopterus variegatus] 
ENSG00000033030(ZCCHC8)	--	9.767288371	550	10.15534029	588	11.3559459	658	10.33182604	617	10.34269085	600	12.79509957	743	0.964323704	0.134651347	normal	0.972905216	0.007700183	normal	0.961038687	0.166622605	normal	0.695026169	0.105662726	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	"K13128|0|hsa:55596|ZCCHC8; zinc finger, CCHC domain containing 8; K13128 zinc finger CCHC domain-containing protein 8 (A)"	--	[S]	Function unknown	PSP;; Zinc knuckle	Zinc finger CCHC domain-containing protein 8 GN=ZCCHC8 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: zinc finger CCHC domain-containing protein 8 [Ceratotherium simum simum]
ENSG00000033050(ABCF2)	--	32.81186332	2256	30.95588818	2260	33.50266845	2464	35.95314046	2564	36.83231013	2538	33.15675478	2270	0.981622606	0.1536987	normal	0.982152067	0.145850605	normal	0.984016162	-0.126520472	normal	0.820476404	0.057461461	normal	--	--	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K06185|0|hsa:10061|ABCF2, ABC28, EST133090, HUSSY18; ATP-binding cassette, sub-family F (GCN20), member 2; K06185 ATP-binding cassette, subfamily F, member 2 (A)"	--	[R]	General function prediction only	ABC transporter;; ABC transporter;; AAA domain;; P-loop containing region of AAA domain;; Miro-like protein	ATP-binding cassette sub-family F member 2 GN=ABCF2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ATP-binding cassette sub-family F member 2 isoform X3 [Mustela putorius furo]
ENSG00000033100(CHPF2)	--	22.63698777	1423	21.00983954	1454	18.75928644	1297	25.39393905	1685	30.90175323	1890	23.01985655	1497	0.963237836	0.212769365	normal	0.853425638	0.356606267	normal	0.965191514	0.198388818	normal	0.129783684	0.259501134	normal	--	--	"Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; Cellular Component: Golgi cisterna membrane (GO:0032580);; "	"K03419|0|hsa:54480|CHPF2, CSGLCA-T, CSGlcAT, ChSy-3, chPF-2; chondroitin polymerizing factor 2 (EC:2.4.1.226); K03419 chondroitin polymerizing factor 2 [EC:2.4.1.226] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[S]	Function unknown	Chondroitin N-acetylgalactosaminyltransferase;; Fringe-like	Chondroitin sulfate glucuronyltransferase GN=CHPF2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: chondroitin sulfate glucuronyltransferase isoform X1 [Equus przewalskii]
ENSG00000033170(FUT8)	--	7.229340054	484	7.09757035	467	5.495045512	387	12.135687	790	14.26172404	969	13.39673433	833	0.019127505	0.674322591	normal	1.20E-06	1.029284305	up	1.55E-07	1.09470527	up	3.25E-09	0.932698737	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K00717|0|ptr:449506|FUT8; fucosyltransferase 8 (alpha (1,6) fucosyltransferase) (EC:2.4.1.68); K00717 glycoprotein 6-alpha-L-fucosyltransferase [EC:2.4.1.68] (A)"	N-Glycan biosynthesis (ko00510);; Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Transcriptional misregulation in cancer (ko05202)	[O]	"Posttranslational modification, protein turnover, chaperones"	Variant SH3 domain;; SH3 domain	"Alpha-(1,6)-fucosyltransferase GN=FUT8 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: alpha-(1,6)-fucosyltransferase-like isoform X1 [Tupaia chinensis] "
ENSG00000033178(UBA6)	--	10.85867672	1264	11.00378541	1273	13.98865025	1412	11.96324033	1548	9.80617997	1143	9.341950389	1119	0.940934254	0.261289363	normal	0.967323958	-0.176612021	normal	0.85613455	-0.343407366	normal	0.822776504	-0.073794489	normal	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	"K10699|0|hsa:55236|UBA6, E1-L2, MOP-4, UBE1L2; ubiquitin-like modifier activating enzyme 6; K10699 ubiquitin-activating enzyme E1-like protein 2 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	ThiF family;; Ubiquitin-activating enzyme e1 C-terminal domain;; Repeat in ubiquitin-activating (UBA) protein;; Ubiquitin-activating enzyme active site	Ubiquitin-like modifier-activating enzyme 6 GN=UBA6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like modifier-activating enzyme 6 isoform X1 [Pteropus alecto]
ENSG00000033327(GAB2)	--	2.935291385	386	2.00335148	291	2.742459759	391	3.512966446	497	2.726551304	386	2.906114876	414	0.857493876	0.33264332	normal	0.795245709	0.384415463	normal	0.967357332	0.073892942	normal	0.301470872	0.258735459	normal	--	--	--	K08091|0|ptr:748918|GAB2; GRB2-associated binding protein 2; K08091 growth factor receptor bound protein 2-associated protein 2 (A)	Ras signaling pathway (ko04014);; Sphingolipid signaling pathway (ko04071);; Osteoclast differentiation (ko04380);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Chronic myeloid leukemia (ko05220)	--	--	PH domain;; Pleckstrin homology domain	GRB2-associated-binding protein 2 GN=GAB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: GRB2-associated-binding protein 2 [Felis catus]
ENSG00000033627(ATP6V0A1)	--	21.49458557	1451	24.01555442	1603	21.25021346	1464	19.90978072	1390	16.08005815	1103	25.82884857	1815	0.980563124	-0.092694602	normal	0.146966515	-0.560127161	normal	0.917792003	0.301482348	normal	0.837977777	-0.089215623	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V0 domain (GO:0033179);; "	"K02154|0|hsa:535|ATP6V0A1, ATP6N1, ATP6N1A, Stv1, VPP1, Vph1, a1; ATPase, H+ transporting, lysosomal V0 subunit a1 (EC:3.6.3.14); K02154 V-type H+-transporting ATPase subunit a (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Tuberculosis (ko05152);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	V-type ATPase 116kDa subunit family	V-type proton ATPase 116 kDa subunit a isoform 1 GN=ATP6V0A1 OS=Homo sapiens (Human) PE=2 SV=3	C	Energy production and conversion	PREDICTED: V-type proton ATPase 116 kDa subunit a isoform 1 isoformX1 [Equus caballus] 
ENSG00000033800(PIAS1)	--	12.7599041	1062	12.134551	987	12.98007273	1084	11.23062	988	11.11616562	1001	10.18654574	891	0.97203508	-0.134830777	normal	0.979014308	-0.001104892	normal	0.910457048	-0.290710762	normal	0.510659965	-0.142820366	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K04706|0|pps:100995827|PIAS1; protein inhibitor of activated STAT, 1; K04706 E3 SUMO-protein ligase PIAS1 [EC:6.3.2.-] (A)"	Ubiquitin mediated proteolysis (ko04120);; Jak-STAT signaling pathway (ko04630);; Hepatitis C (ko05160)	[K]	Transcription	PINIT domain;; MIZ/SP-RING zinc finger	E3 SUMO-protein ligase PIAS1 GN=PIAS1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: E3 SUMO-protein ligase PIAS1 isoform 1 [Ceratotherium simum simum]
ENSG00000033867(SLC4A7)	--	19.77214135	2060	22.89316205	2376	22.98622238	2341	20.56144804	2128	16.94317254	1768	15.8099301	1676	0.987229671	0.016009802	normal	0.613101685	-0.447511604	normal	0.395564505	-0.49001831	normal	0.06099714	-0.304347708	normal	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13858|0|pon:100432357|SLC4A7; solute carrier family 4, sodium bicarbonate cotransporter, member 7; K13858 solute carrier family 4 (sodium bicarbonate cotransporter), member 7 (A)"	--	[P]	Inorganic ion transport and metabolism	HCO3- transporter family;; Band 3 cytoplasmic domain	Sodium bicarbonate cotransporter 3 GN=SLC4A7 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium bicarbonate cotransporter 3 isoform X1 [Orycteropus afer afer]
ENSG00000034053(APBA2)	--	12.86324481	756	13.83459073	889	9.735840122	728	21.27309218	1102	14.30790191	1023	20.78504183	1066	0.289680536	0.511967519	normal	0.96231406	0.180837313	normal	0.193599283	0.540971517	normal	0.01340638	0.405730904	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Phosphotyrosine interaction domain (PTB/PID);; PDZ domain (Also known as DHR or GLGF)	Amyloid beta A4 precursor protein-binding family A member 2 GN=APBA2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: amyloid beta A4 precursor protein-binding family A member 2 isoform X1 [Galeopterus variegatus] 
ENSG00000034152(MAP2K3)	--	27.23219732	1187	27.15494811	1205	28.94112141	1304	27.26557391	1187	24.029708	1052	33.15354609	1404	0.981181061	-0.030792407	normal	0.955322056	-0.217033218	normal	0.979623808	0.098197851	normal	0.884470606	-0.041422357	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04432|0|pon:100457536|MAP2K3; mitogen-activated protein kinase kinase 3; K04432 mitogen-activated protein kinase kinase 3 [EC:2.7.12.2] (A)	MAPK signaling pathway (ko04010);; Rap1 signaling pathway (ko04015);; Toll-like receptor signaling pathway (ko04620);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Toxoplasmosis (ko05145);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Dual specificity mitogen-activated protein kinase kinase 3 GN=MAP2K3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity mitogen-activated protein kinase kinase 3 [Canis lupus familiaris]
ENSG00000034239(EFCAB1)	--	0	0	0	0	0	0	0.139493577	2	0.0278584	0	0.136466145	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair	EF-hand calcium-binding domain-containing protein 1 GN=EFCAB1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: EF-hand calcium-binding domain-containing protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000034510(TMSB10)	--	3892.51	20140	3553.67	19220	3552.33	19629	3811.62	21719	3290.58	16978	3588.75	19472	0.99772166	0.078055998	normal	0.994534536	-0.200351588	normal	0.997835789	-0.019875508	normal	0.896561008	-0.041821859	normal	--	--	--	"K13785|1.9268e-22|rno:50665|Tmsb10, Ptmb10, THYb10; thymosin, beta 10; K13785 thymosin beta 10 (A)"	--	[N]	Cell motility	--	Thymosin beta-10 GN=TMSB10 OS=Homo sapiens (Human) PE=1 SV=2	N	Cell motility	PREDICTED: thymosin beta-10 [Odobenus rosmarus divergens]
ENSG00000034533(ASTE1)	--	1.841283	78	1.975344	84	1.466008	67	2.25614	106	2.212472	94	2.072974	82	0.91172348	0.404823338	normal	0.966560478	0.138487132	normal	0.9579624	0.277500865	normal	0.595231857	0.278037968	normal	--	--	Molecular Function: nuclease activity (GO:0004518);; Biological Process: DNA repair (GO:0006281);; 	--	--	--	--	XPG domain containing;; XPG N-terminal domain	Protein asteroid homolog 1 GN=ASTE1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein asteroid homolog 1 [Ceratotherium simum simum]
ENSG00000034677(RNF19A)	--	7.506918772	565	7.842149757	592	9.335000705	571	14.3756351	1046	14.67891105	1103	19.36200435	1380	0.00013123	0.855991881	normal	9.58E-05	0.87467507	normal	3.74E-11	1.262593877	up	4.39E-07	1.009759295	up	--	--	--	"K11972|0|ptr:464315|RNF19A, RNF19; ring finger protein 19A, RBR E3 ubiquitin protein ligase; K11972 E3 ubiquitin-protein ligase RNF19A [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain	E3 ubiquitin-protein ligase RNF19A GN=RNF19A OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF19A isoform X1 [Ailuropoda melanoleuca] 
ENSG00000034693(PEX3)	--	6.7765671	179	7.876126042	196	6.732397344	165	7.685916532	205	7.384432415	184	6.936043924	181	0.956022914	0.163519854	normal	0.961038645	-0.111684858	normal	0.961644386	0.124145513	normal	0.910966243	0.056164845	normal	--	--	Cellular Component: integral component of peroxisomal membrane (GO:0005779);; Biological Process: peroxisome organization (GO:0007031);; 	"K13336|0|hsa:8504|PEX3, PBD10A, TRG18; peroxisomal biogenesis factor 3; K13336 peroxin-3 (A)"	Peroxisome (ko04146)	[MU]	"Cell wall/membrane/envelope biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	Peroxin-3	Peroxisomal biogenesis factor 3 GN=PEX3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal biogenesis factor 3 [Tupaia chinensis]
ENSG00000034713(GABARAPL2)	--	72.06515639	839	70.59533821	827	65.15018804	759	67.98239265	808	63.54596189	742	66.60765618	777	0.974251454	-0.084989167	normal	0.959796578	-0.177551721	normal	0.976294647	0.025473107	normal	0.760492236	-0.08101334	normal	--	--	Biological Process: autophagic vacuole assembly (GO:0000045);; Cellular Component: cytoplasm (GO:0005737);; 	K08341|2.41697e-81|ssc:100521968|GABARAPL2; GABA(A) receptor-associated protein-like 2; K08341 GABA(A) receptor-associated protein (A)	FoxO signaling pathway (ko04068);; Regulation of autophagy (ko04140);; GABAergic synapse (ko04727)	[Z]	Cytoskeleton	Autophagy protein Atg8 ubiquitin like;; Ubiquitin-like autophagy protein Apg12	Gamma-aminobutyric acid receptor-associated protein-like 2 (Precursor) GN=GABARAPL2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: uncharacterized protein LOC100931278 [Sarcophilus harrisii]
ENSG00000035115(SH3YL1)	--	5.591471887	240	4.687404853	239	4.282619477	233	3.63287405	159	3.421787849	140	4.834170816	222	0.275684425	-0.619926595	normal	0.035811294	-0.786427975	normal	0.964619538	-0.077546029	normal	0.096151771	-0.470863177	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Family of unknown function (DUF500);; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	SH3 domain-containing YSC84-like protein 1 GN=SH3YL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: SH3 domain-containing YSC84-like protein 1 isoform X3 [Felis catus] 
ENSG00000035141(FAM136A)	--	52.978059	1658	57.194066	1826	55.56781679	1781	48.37321133	1553	42.114358	1294	41.24769322	1314	0.979424315	-0.125098625	normal	0.28802094	-0.517763593	normal	0.572570668	-0.446570456	normal	0.021652866	-0.361244817	normal	--	--	--	--	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF842)	Protein FAM136A GN=FAM136A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM136A [Canis lupus familiaris]
ENSG00000035403(VCL)	--	84.22718718	9240	77.27680475	8445	87.54337671	9635	110.1169161	12118	93.24398402	10146	74.6166951	8256	0.947003335	0.36030214	normal	0.986167209	0.243275388	normal	0.98732672	-0.231093912	normal	0.644620054	0.13762457	normal	--	--	Biological Process: cell adhesion (GO:0007155);; Molecular Function: actin filament binding (GO:0051015);; 	K05700|0|cjc:100410985|VCL; vinculin; K05700 vinculin (A)	Focal adhesion (ko04510);; Adherens junction (ko04520);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Amoebiasis (ko05146)	[W]	Extracellular structures	Vinculin family	Vinculin GN=VCL OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: vinculin isoformX2 [Equus caballus]
ENSG00000035499(DEPDC1B)	--	12.34717936	491	12.54565597	499	12.23397359	477	13.10692856	527	11.82007963	470	10.3218596	397	0.96961071	0.071033108	normal	0.965209259	-0.107469947	normal	0.913645903	-0.27219437	normal	0.753459943	-0.095738712	normal	--	--	Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	"Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; RhoGAP domain"	DEP domain-containing protein 1B GN=DEPDC1B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DEP domain-containing protein 1B [Tupaia chinensis] 
ENSG00000035664(DAPK2)	--	1.479032646	81	2.089154824	91	1.995163522	87	1.630465653	68	2.260043776	114	2.690120746	96	0.958317826	-0.277466555	normal	0.940003715	0.299218242	normal	0.967980468	0.131549959	normal	0.907081753	0.082039339	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08803|0|pps:100972913|DAPK2; death-associated protein kinase 2; K08803 death-associated protein kinase [EC:2.7.11.1] (A)	Pathways in cancer (ko05200);; Bladder cancer (ko05219)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; RIO1 family	Death-associated protein kinase 2 GN=DAPK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: death-associated protein kinase 3 isoform X1 [Panthera tigris altaica]
ENSG00000035681(NSMAF)	--	14.22932	990	15.40007	1068	15.63923	1075	18.20106	1267	17.10822	1184	17.26066	1199	0.878100809	0.324637547	normal	0.973969908	0.127159815	normal	0.971611072	0.149004987	normal	0.298399295	0.199039446	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K18953|0|hsa:8439|NSMAF, FAN; neutral sphingomyelinase (N-SMase) activation associated factor; K18953 factor associated with neutral sphingomyelinase activation (A)"	Sphingolipid signaling pathway (ko04071)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; WD domain, G-beta repeat;; GRAM domain;; PH domain associated with Beige/BEACH"	Protein FAN GN=NSMAF OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	neutral sphingomyelinase (N-SMase) activation associated factor precursor [Equus caballus]
ENSG00000035687(ADSS)	--	32.8959	1427	33.8128	1489	35.5031	1529	36.7297	1607	31.1229	1344	33.5528	1449	0.976948403	0.140409819	normal	0.971441617	-0.16905635	normal	0.981606627	-0.085735134	normal	0.898024716	-0.036179144	normal	[F]	Nucleotide transport and metabolism	Molecular Function: adenylosuccinate synthase activity (GO:0004019);; Molecular Function: GTP binding (GO:0005525);; Biological Process: purine nucleotide biosynthetic process (GO:0006164);; 	"K01939|0|hsa:159|ADSS, ADEH, ADSS_2; adenylosuccinate synthase (EC:6.3.4.4); K01939 adenylosuccinate synthase [EC:6.3.4.4] (A)"	"Purine metabolism (ko00230);; Alanine, aspartate and glutamate metabolism (ko00250)"	[F]	Nucleotide transport and metabolism	Adenylosuccinate synthetase	Adenylosuccinate synthetase isozyme 2 {ECO:0000255|HAMAP-Rule:MF_03127} OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: adenylosuccinate synthetase isozyme 2-like [Tursiops truncatus]
ENSG00000035862(TIMP2)	--	174.6452695	10977	180.9633618	11388	172.9272208	10885	160.3131441	10025	147.2116095	9216	158.2888215	9996	0.99377875	-0.161690155	normal	0.966835218	-0.326680008	normal	0.994778984	-0.131191017	normal	0.31143052	-0.206849111	normal	--	--	Molecular Function: metalloendopeptidase inhibitor activity (GO:0008191);; 	--	--	[R]	General function prediction only	Tissue inhibitor of metalloproteinase	Metalloproteinase inhibitor 2 (Precursor) GN=TIMP2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: metalloproteinase inhibitor 2 [Equus przewalskii]
ENSG00000035928(RFC1)	--	13.76074191	1330	13.81152896	1393	14.21893864	1435	13.57261065	1328	12.45576427	1278	12.17936655	1252	0.982401569	-0.032965252	normal	0.974154053	-0.145568922	normal	0.962712877	-0.204876271	normal	0.543659476	-0.129321049	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA clamp loader activity (GO:0003689);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: DNA replication factor C complex (GO:0005663);; Biological Process: DNA replication (GO:0006260);; 	"K10754|0|hsa:5981|RFC1, A1, MHCBFB, PO-GA, RECC1, RFC, RFC140; replication factor C (activator 1) 1, 145kDa; K10754 replication factor C subunit 1 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430)	[L]	"Replication, recombination and repair"	Replication factor RFC1 C terminal domain;; BRCA1 C Terminus (BRCT) domain;; ATPase family associated with various cellular activities (AAA);; AAA domain;; twin BRCT domain	Replication factor C subunit 1 GN=RFC1 OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: replication factor C subunit 1 isoform X1 [Equus caballus]
ENSG00000036054(TBC1D23)	--	9.5345943	547	10.07754311	584	10.47204739	596	11.67326507	685	10.88434901	629	10.68049354	620	0.898714299	0.29299423	normal	0.969870511	0.085451846	normal	0.972883118	0.048543671	normal	0.569524012	0.141890213	normal	--	--	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; Rhodanese-like domain	TBC1 domain family member 23 GN=TBC1D23 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: TBC1 domain family member 23 isoform X3 [Canis lupus familiaris]
ENSG00000036257(CUL3)	--	34.34139279	2272	34.02559389	2219	34.9902012	2299	22.2547913	1498	24.38246005	1592	20.19787886	1355	0.028099779	-0.631227583	normal	0.372684435	-0.500091505	normal	0.00068759	-0.770337141	normal	6.56E-06	-0.632604832	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	K03869|0|ptr:744812|CUL3; cullin 3; K03869 cullin 3 (A)	Ubiquitin mediated proteolysis (ko04120)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cullin family;; Cullin protein neddylation domain	Cullin-3 GN=CUL3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	cullin-3 [Bos taurus] 
ENSG00000036448(MYOM2)	--	2.139754034	60	2.49517444	62	1.756620161	43	2.188824398	58	1.584485	38	2.491660527	61	0.976338009	-0.077717522	normal	0.807014039	-0.705495797	normal	0.934695901	0.481885845	normal	0.913836245	-0.093508547	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Natural killer cell receptor 2B4	Myomesin-2 GN=MYOM2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: myomesin-2 [Tupaia chinensis]
ENSG00000036530(CYP46A1)	--	0.079769336	2	0.039046322	1	0	0	0.074574221	3	0.121346135	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07440|0|hsa:10858|CYP46A1, CP46, CYP46; cytochrome P450, family 46, subfamily A, polypeptide 1 (EC:1.14.13.98); K07440 cholesterol 24(S)-hydroxylase [EC:1.14.13.98] (A)"	Primary bile acid biosynthesis (ko00120)	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cholesterol 24-hydroxylase GN=CYP46A1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cholesterol 24-hydroxylase-like isoform X1 [Condylura cristata]
ENSG00000036549(ZZZ3)	--	8.383119	584	9.36742	644	9.258896	661	9.304261	651	9.2928116	724	11.38052	797	0.966336635	0.125543987	normal	0.963849064	0.147176361	normal	0.925551049	0.261093268	normal	0.421912358	0.180946457	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	"Myb-like DNA-binding domain;; Myb-like DNA-binding domain;; Zinc finger, ZZ type"	ZZ-type zinc finger-containing protein 3 GN=ZZZ3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ZZ-type zinc finger-containing protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000036672(USP2)	--	0.572779582	31	0.411347723	23	0.340700907	17	0.55014926	29	0.600230949	33	0.470598291	26	0.984454166	-0.120853074	normal	0.970228937	0.473308829	normal	0.974401774	0.563868021	normal	0.74601295	0.287595672	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11833|0|ptr:451610|USP2; ubiquitin specific peptidase 2; K11833 ubiquitin carboxyl-terminal hydrolase 2/21 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 2 GN=USP2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 2 isoform X2 [Felis catus]
ENSG00000036828(CASR)	--	0.301628089	57	0.348708519	66	0.267466967	50	0.413666484	78	0.277834192	52	0.299488684	57	0.934993597	0.412150912	normal	0.952574387	-0.356163722	normal	0.974313255	0.175760426	normal	0.911558094	0.089538449	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04612|0|pon:100459602|CASR; calcium-sensing receptor; K04612 calcium-sensing receptor (A)	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Nine Cysteines Domain of family 3 GPCR;; Periplasmic binding protein	Extracellular calcium-sensing receptor (Precursor) GN=CASR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: extracellular calcium-sensing receptor isoform X1 [Lipotes vexillifer]
ENSG00000037042(TUBG2)	--	7.76251	271	5.42133	189	7.82469	277	6.51868	227	6.5409	228	5.3263	187	0.913743616	-0.284666596	normal	0.93339258	0.247416414	normal	0.361047364	-0.571318086	normal	0.510666523	-0.220385775	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	K10389|0|pps:100992398|TUBG2; tubulin gamma-2 chain; K10389 tubulin gamma (A)	--	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin gamma-2 chain GN=TUBG2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	tubulin gamma-2 chain [Bos taurus] 
ENSG00000037241(RPL26L1)	--	47.84545317	489	58.28849641	524	48.98782313	513	63.027181	637	61.50277	622	66.615962	684	0.829268945	0.34966173	normal	0.939914295	0.225323748	normal	0.707361947	0.405706882	normal	0.100259253	0.327546933	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Biological Process: translation (GO:0006412);; Cellular Component: large ribosomal subunit (GO:0015934);; 	K02898|1.67906e-86|pps:100980395|RPL26L1; ribosomal protein L26-like 1; K02898 large subunit ribosomal protein L26e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	KOW motif	60S ribosomal protein L26-like 1 GN=RPL26L1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L26-like 1 isoform X2 [Physeter catodon]
ENSG00000037280(FLT4)	--	1.681639922	200	2.54706099	147	2.3624723	171	1.670219866	105	1.395170906	149	0.722513262	87	0.00487985	-0.950185911	normal	0.966641761	-0.001910857	normal	0.00799663	-0.970933732	normal	0.048962148	-0.624578237	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05097|0|nle:100582920|FLT4; fms-related tyrosine kinase 4; K05097 FMS-like tyrosine kinase 4 [EC:2.7.10.1] (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain	Vascular endothelial growth factor receptor 3 (Precursor) GN=FLT4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: vascular endothelial growth factor receptor 3 [Odobenus rosmarus divergens]
ENSG00000037474(NSUN2)	--	36.28824	2396	35.63774	2393	35.52386	2355	36.54038	2405	38.30419	2519	32.32971	2139	0.988335348	-0.025407016	normal	0.987714086	0.052571785	normal	0.981500337	-0.146982939	normal	0.891105128	-0.037958011	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; 	"K15335|0|pps:100978191|NSUN2; NOP2/Sun RNA methyltransferase family, member 2; K15335 tRNA (cytosine34-C5)-methyltransferase [EC:2.1.1.203] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	NOL1/NOP2/sun family	tRNA (cytosine(34)-C(5))-methyltransferase GN=NSUN2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: tRNA (cytosine(34)-C(5))-methyltransferase [Tupaia chinensis]
ENSG00000037637(FBXO42)	--	3.875680023	385	4.177486288	396	4.305727728	393	4.578913	405	5.073656787	394	4.822142001	398	0.968799988	0.042067515	normal	0.968435831	-0.028621778	normal	0.969661915	0.009909783	normal	0.990396904	0.006748746	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10317|0|hsa:54455|FBXO42, Fbx42, JFK; F-box protein 42; K10317 F-box protein 42 (A)"	--	[R]	General function prediction only	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Kelch motif;; F-box-like;; F-box domain"	F-box only protein 42 GN=FBXO42 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box only protein 42 [Trichechus manatus latirostris]
ENSG00000037749(MFAP3)	--	9.569416465	677	14.84811653	800	16.33538849	726	12.98536606	816	13.09722787	876	14.64679098	824	0.938275932	0.238088342	normal	0.971812394	0.109306807	normal	0.960886152	0.174042844	normal	0.43366953	0.170474619	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	Microfibril-associated glycoprotein 3 (Precursor) GN=MFAP3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: microfibril-associated glycoprotein 3 [Ceratotherium simum simum]
ENSG00000037757(MRI1)	--	90.628416	1387	107.2981345	1551	93.124905	1459	84.866841	1290	87.340221	1294	82.16392266	1240	0.975828421	-0.135273553	normal	0.929186675	-0.282485604	normal	0.949358956	-0.242658055	normal	0.216962557	-0.22276581	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: cellular metabolic process (GO:0044237);; 	"K08963|0|hsa:84245|MRI1, MRDI, MTNA, Ypr118w; methylthioribose-1-phosphate isomerase 1 (EC:5.3.1.23); K08963 methylthioribose-1-phosphate isomerase [EC:5.3.1.23] (A)"	Cysteine and methionine metabolism (ko00270)	[J]	"Translation, ribosomal structure and biogenesis"	Initiation factor 2 subunit family	Methylthioribose-1-phosphate isomerase {ECO:0000255|HAMAP-Rule:MF_03119} GN=UNQ6390/PRO21135 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: methylthioribose-1-phosphate isomerase [Myotis lucifugus]
ENSG00000037897(METTL1)	--	7.7949087	258	9.0287056	287	6.7417031	257	9.5028665	317	13.680269	416	8.115925	254	0.921381845	0.264854626	normal	0.440242327	0.511854291	normal	0.967002784	-0.025082837	normal	0.464352804	0.277749017	normal	--	--	Biological Process: tRNA modification (GO:0006400);; Molecular Function: tRNA (guanine-N7-)-methyltransferase activity (GO:0008176);; 	"K03439|0|hsa:4234|METTL1, C12orf1, TRM8, TRMT8, YDL201w; methyltransferase like 1 (EC:2.1.1.33); K03439 tRNA (guanine-N7-)-methyltransferase [EC:2.1.1.33] (A)"	--	[R]	General function prediction only	Putative methyltransferase	tRNA (guanine-N(7)-)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03055} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (guanine-N(7)-)-methyltransferase [Camelus ferus] 
ENSG00000037965(HOXC8)	--	2.083284	75	1.515888	52	1.27613	45	3.5802	131	3.18145	114	1.701144	63	0.26965166	0.761825992	normal	0.015487186	1.089120661	normal	0.936583031	0.463902606	normal	0.146747042	0.816901352	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09308|3.2124e-163|hsa:3224|HOXC8, HOX3, HOX3A; homeobox C8; K09308 homeobox protein HoxB/C/D8 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-C8 GN=HOXC8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein Hox-C8 [Trichechus manatus latirostris]
ENSG00000038002(AGA)	--	11.39721301	374	9.007316857	298	8.417545732	261	9.229787005	308	8.3901961	274	11.9827111	395	0.887634561	-0.309536286	normal	0.957008669	-0.141812189	normal	0.206867984	0.586728872	normal	0.936208879	0.045614333	normal	[E]	Amino acid transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	K01444|0|ptr:461616|AGA; aspartylglucosaminidase; K01444 N4-(beta-N-acetylglucosaminyl)-L-asparaginase [EC:3.5.1.26] (A)	Other glycan degradation (ko00511);; Lysosome (ko04142)	[E]	Amino acid transport and metabolism	Asparaginase	Glycosylasparaginase beta chain (Precursor) GN=AGA OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase isoform X1 [Ailuropoda melanoleuca]
ENSG00000038210(PI4K2B)	--	7.605897001	396	6.002367076	306	7.033063247	358	10.75228927	562	8.76286	460	8.492655	443	0.506252022	0.472691098	normal	0.2461762	0.564386229	normal	0.89510457	0.29792232	normal	0.031639746	0.44495263	normal	--	--	Molecular Function: kinase activity (GO:0016301);; 	"K13711|0|hsa:55300|PI4K2B, PI4KIIB, PIK42B; phosphatidylinositol 4-kinase type 2 beta (EC:2.7.1.67); K13711 phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	Phosphatidylinositol 3- and 4-kinase	Phosphatidylinositol 4-kinase type 2-beta GN=PI4K2B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-kinase type 2-beta [Oryctolagus cuniculus]
ENSG00000038219(BOD1L1)	--	9.743101989	2688	11.3184	2791	11.16242	3028	8.921900107	2454	10.485902	2770	9.478024	2515	0.981499425	-0.162133113	normal	0.989145275	-0.032305135	normal	0.953125996	-0.275946796	normal	0.420530352	-0.157386073	normal	--	--	--	--	--	--	--	COMPASS (Complex proteins associated with Set1p) component shg1	Biorientation of chromosomes in cell division protein 1-like 1 GN=BOD1L1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: biorientation of chromosomes in cell division protein 1-like 1 [Ceratotherium simum simum]
ENSG00000038274(MAT2B)	--	30.4585752	1063	29.97389235	1049	30.27974859	1043	38.166281	1335	32.2718	1115	35.96266443	1248	0.90990053	0.297481534	normal	0.978378152	0.066509467	normal	0.941671972	0.250255202	normal	0.26914883	0.207614376	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K00789|0|pps:100968203|MAT2B; methionine adenosyltransferase II, beta; K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] (A)"	Cysteine and methionine metabolism (ko00270);; Biosynthesis of amino acids (ko01230)	[IE]	Lipid transport and metabolism;; Amino acid transport and metabolism	RmlD substrate binding domain;; NAD dependent epimerase/dehydratase family;; NADH(P)-binding;; Polysaccharide biosynthesis protein;; Male sterility protein;; 3-beta hydroxysteroid dehydrogenase/isomerase family	Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: methionine adenosyltransferase 2 subunit beta isoform X1 [Oryctolagus cuniculus]
ENSG00000038295(TLL1)	--	0.117946503	14	0.401575411	33	0.297493069	27	1.201892566	110	2.292934999	160	1.178830074	121	1.39E-12	2.814689478	up	5.72E-12	2.205605094	up	4.39E-09	2.095250352	up	5.64E-11	2.380906878	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: proteolysis (GO:0006508);; 	K09608|0|mcc:705831|TLL1; tolloid-like 1; K09608 tolloid-like protein 1 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	CUB domain;; Astacin (Peptidase family M12A);; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; EGF-like domain	Tolloid-like protein 1 (Precursor) GN=TLL1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tolloid-like protein 1 isoform X2 [Equus przewalskii]
ENSG00000038358(EDC4)	--	12.861301	1312	13.76023387	1367	13.200443	1376	14.944134	1470	14.97112106	1516	17.17656484	1579	0.976609392	0.133068904	normal	0.977378604	0.127695767	normal	0.968226574	0.190044139	normal	0.461736925	0.14998424	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12616|0|hsa:23644|EDC4, GE1, Ge-1, HEDL5, HEDLS, RCD-8, RCD8; enhancer of mRNA decapping 4; K12616 enhancer of mRNA-decapping protein 4 (A)"	RNA degradation (ko03018)	[R]	General function prediction only	"WD domain, G-beta repeat"	Enhancer of mRNA-decapping protein 4 GN=EDC4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: enhancer of mRNA-decapping protein 4 isoform X3 [Galeopterus variegatus]
ENSG00000038382(TRIO)	--	25.84105613	4905	27.12011274	5593	22.89394092	5142	38.51062002	7565	33.82603767	6729	29.90202053	6317	0.101769031	0.594103777	normal	0.980628074	0.245282697	normal	0.967041714	0.288541829	normal	0.020689567	0.376354485	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K08810|0|hsa:7204|TRIO, ARHGEF23, tgat; trio Rho guanine nucleotide exchange factor (EC:2.7.11.1); K08810 triple functional domain protein [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Protein kinase domain;; Spectrin repeat;; Protein tyrosine kinase;; Divergent CRAL/TRIO domain;; Immunoglobulin I-set domain;; SH3 domain;; PH domain;; Immunoglobulin domain;; Immunoglobulin domain;; Pleckstrin homology domain;; CRAL/TRIO domain;; Variant SH3 domain	Triple functional domain protein GN=TRIO OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: triple functional domain protein [Orcinus orca]
ENSG00000038427(VCAN)	--	2.210372359	440	1.370067749	285	1.81340865	361	21.80036212	4549	29.36104304	6175	25.3828482	5211	0	3.334658683	up	0	4.408756099	up	0	3.837604129	up	4.16E-41	3.854502965	up	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	K06793|0|pps:100993269|VCAN; versican; K06793 versican core protein (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Extracellular link domain;; Lectin C-type domain;; Immunoglobulin V-set domain;; EGF-like domain;; Sushi domain (SCR repeat)	Versican core protein (Precursor) GN=VCAN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: versican core protein isoform X3 [Galeopterus variegatus]
ENSG00000038532(CLEC16A)	--	6.477940771	683	6.42904898	659	6.141420645	647	6.830467471	796	5.672472593	749	7.340035	835	0.956017387	0.18965512	normal	0.961318139	0.162909849	normal	0.813381792	0.358978542	normal	0.237806777	0.237785031	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein	Protein CLEC16A {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein CLEC16A isoform X3 [Tupaia chinensis]
ENSG00000039068(CDH1)	--	17.37093694	1684	10.30386172	999	12.95374739	1234	15.2004196	1477	22.83993219	2212	25.63282161	2495	0.961481211	-0.219840204	normal	5.68E-09	1.124195449	up	2.40E-07	1.006520792	up	0.151141687	0.639132099	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K05689|0|hsa:999|CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO; cadherin 1, type 1, E-cadherin (epithelial); K05689 cadherin 1, type 1, E-cadherin (A)"	Rap1 signaling pathway (ko04015);; Hippo signaling pathway (ko04390);; Cell adhesion molecules (CAMs) (ko04514);; Adherens junction (ko04520);; Bacterial invasion of epithelial cells (ko05100);; Pathogenic Escherichia coli infection (ko05130);; Pathways in cancer (ko05200);; Endometrial cancer (ko05213);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin prodomain like	E-Cad/CTF3 (Precursor) GN=CDH1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: cadherin-1 isoform X2 [Oryctolagus cuniculus]
ENSG00000039123(SKIV2L2)	--	23.12218371	1721	26.58359	1991	27.20064076	1980	21.43063513	1666	22.528017	1703	20.017802	1523	0.983472926	-0.077620523	normal	0.955812503	-0.246638543	normal	0.786374256	-0.386538301	normal	0.167589895	-0.239843588	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K12598|0|hsa:23517|SKIV2L2, Dob1, KIAA0052, Mtr4, fSAP118; superkiller viralicidic activity 2-like 2 (S. cerevisiae) (EC:3.6.4.13); K12598 ATP-dependent RNA helicase DOB1 [EC:3.6.4.13] (A)"	RNA degradation (ko03018)	[A]	RNA processing and modification	rRNA-processing arch domain;; DSHCT (NUC185) domain;; DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Superkiller viralicidic activity 2-like 2 GN=SKIV2L2 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: superkiller viralicidic activity 2-like 2 [Mustela putorius furo] 
ENSG00000039139(DNAH5)	--	0.42440377	135	0.554054142	176	0.31098179	97	0.73168349	233	0.52945794	167	0.642953211	205	0.065688461	0.749968083	normal	0.962738149	-0.096304245	normal	0.000728791	1.059654587	up	0.120712638	0.545795915	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:1767|DNAH5, CILD3, DNAHC5, HL1, KTGNR, PCD; dynein, axonemal, heavy chain 5; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 1;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D4;; ATP-binding dynein motor region D5;; P-loop containing dynein motor region D3;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA)"	"Dynein heavy chain 5, axonemal GN=DNAH5 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 5, axonemal [Equus caballus]"
ENSG00000039319(ZFYVE16)	--	11.79337099	1312	12.54887043	1381	12.15640294	1320	10.93193726	1222	11.21879134	1249	12.21529277	1365	0.975301611	-0.133194025	normal	0.970727496	-0.166174953	normal	0.9823846	0.040026483	normal	0.716297523	-0.085984925	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K04679|0|hsa:9765|ZFYVE16, PPP1R69; zinc finger, FYVE domain containing 16; K04679 MAD, mothers against decapentaplegic interacting protein (A)"	Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350)	[V]	Defense mechanisms	Domain of unknown function (DUF3480);; FYVE zinc finger	Zinc finger FYVE domain-containing protein 16 GN=ZFYVE16 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: zinc finger FYVE domain-containing protein 16 [Orcinus orca]
ENSG00000039523(FAM65A)	--	16.23979324	1274	18.02214836	1380	18.69977804	1474	17.95397528	1368	14.56353737	1124	14.19360493	1120	0.980926951	0.071787135	normal	0.89418351	-0.317067022	normal	0.71823916	-0.404052111	normal	0.24334465	-0.21433376	normal	--	--	--	--	--	--	--	HEAT repeats	Protein FAM65A GN=FAM65A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM65A isoform X1 [Sus scrofa]
ENSG00000039537(C6)	--	0	0	0	0	0	0	0	0	0.02611078	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K03995|0|hsa:729|C6; complement component 6; K03995 complement component 6 (A)	Complement and coagulation cascades (ko04610);; Prion diseases (ko05020);; Systemic lupus erythematosus (ko05322)	--	--	MAC/Perforin domain;; Sushi domain (SCR repeat);; Thrombospondin type 1 domain;; Low-density lipoprotein receptor domain class A;; Kazal-type serine protease inhibitor domain	Complement component C6 (Precursor) GN=C6 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: complement component C6 [Ceratotherium simum simum]
ENSG00000039560(RAI14)	--	43.21758825	3788	36.49937939	3569	42.25036091	3648	60.26248444	5295	61.15622365	5126	54.60835011	4421	0.667837409	0.452206322	normal	0.462106791	0.5007091	normal	0.96607583	0.268874166	normal	0.007929409	0.409826526	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankycorbin GN=RAI14 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankycorbin isoform X1 [Galeopterus variegatus]
ENSG00000039650(PNKP)	--	13.979872	437	20.13523028	579	15.59061763	427	32.92563657	401	11.5313229	362	19.36166972	450	0.957607351	-0.154296737	normal	0.021046615	-0.69667655	normal	0.96854085	0.06716575	normal	0.336096483	-0.271747506	normal	[E]	Amino acid transport and metabolism	--	"K08073|0|hsa:11284|PNKP, EIEE10, MCSZ, PNK; polynucleotide kinase 3'-phosphatase (EC:2.7.1.78 3.1.3.32); K08073 bifunctional polynucleotide phosphatase/kinase [EC:3.1.3.32 2.7.1.78] (A)"	--	[L]	"Replication, recombination and repair"	Polynucleotide kinase 3 phosphatase;; AAA domain;; Haloacid dehalogenase-like hydrolase;; Zeta toxin	Polynucleotide 5'-hydroxyl-kinase GN=PNKP OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: bifunctional polynucleotide phosphatase/kinase [Galeopterus variegatus]
ENSG00000040199(PHLPP2)	--	5.161948	777	4.667651019	694	5.07269681	763	5.28562378	793	5.199991197	764	4.572715502	692	0.976721762	-0.001423211	normal	0.969070024	0.116967432	normal	0.965021995	-0.148892446	normal	0.977448148	-0.01183805	normal	[S]	Function unknown	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: protein binding (GO:0005515);; 	"K16340|0|ptr:454384|PHLPP2, PHLPPL; PH domain and leucine rich repeat protein phosphatase 2; K16340 PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16] (A)"	PI3K-Akt signaling pathway (ko04151)	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Protein phosphatase 2C;; Leucine Rich Repeat;; Leucine rich repeat	PH domain leucine-rich repeat-containing protein phosphatase 2 GN=PHLPP2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: PH domain leucine-rich repeat-containing protein phosphatase 2 isoform X2 [Tupaia chinensis]
ENSG00000040275(SPDL1)	--	17.71281571	925	15.68688005	874	18.23784086	924	28.63387256	1617	30.36050035	1724	25.6100197	1053	0.000770076	0.773978132	normal	3.64E-06	0.95742675	normal	0.963463161	0.179973134	normal	0.03846644	0.668168631	normal	--	--	--	--	--	--	--	--	Protein Spindly {ECO:0000255|HAMAP-Rule:MF_03041} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein Spindly [Camelus dromedarius]
ENSG00000040341(STAU2)	--	25.77678907	1241	25.8873192	1211	26.25233639	1331	21.61964471	1059	23.13970587	1107	21.45288033	1093	0.936639391	-0.259284829	normal	0.971239928	-0.150773186	normal	0.915324883	-0.292141694	normal	0.190714377	-0.236022146	normal	--	--	--	"K17597|0|hsa:27067|STAU2, 39K2, 39K3; staufen double-stranded RNA binding protein 2; K17597 double-stranded RNA-binding protein Staufen (A)"	--	[UK]	"Intracellular trafficking, secretion, and vesicular transport;; Transcription"	Double-stranded RNA binding motif;; double strand RNA binding domain from DEAD END PROTEIN 1	Double-stranded RNA-binding protein Staufen homolog 2 GN=STAU2 OS=Homo sapiens (Human) PE=1 SV=1	KU	"Transcription;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: double-stranded RNA-binding protein Staufen homolog 2 isoform X7 [Oryctolagus cuniculus]
ENSG00000040487(PQLC2)	--	9.487972411	460	12.4577705	584	10.90024188	527	9.4132489	465	10.75590138	493	15.10455218	685	0.970873311	-0.015184964	normal	0.918978684	-0.265059202	normal	0.794135502	0.369078081	normal	0.933794986	0.044584558	normal	--	--	--	--	--	[S]	Function unknown	PQ loop repeat	Lysosomal amino acid transporter 1 homolog GN=PQLC2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lysosomal amino acid transporter 1 homolog [Galeopterus variegatus]
ENSG00000040531(CTNS)	--	8.41969662	368	11.31101903	452	9.37032703	403	9.591528104	370	8.779207442	387	12.63463736	509	0.968838577	-0.022917338	normal	0.928695814	-0.244530544	normal	0.863684789	0.327498496	normal	0.952409551	0.029538672	normal	--	--	--	"K12386|0|hsa:1497|CTNS, CTNS-LSB, PQLC4; cystinosin, lysosomal cystine transporter; K12386 cystinosin (A)"	Lysosome (ko04142)	[E]	Amino acid transport and metabolism	PQ loop repeat	Cystinosin GN=CTNS OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: cystinosin isoform X2 [Galeopterus variegatus]
ENSG00000040608(RTN4R)	--	6.106342866	200	6.399087001	209	6.683262425	229	4.552969	150	4.66237947	149	7.061337001	230	0.785573459	-0.441934301	normal	0.654745941	-0.505265125	normal	0.967040192	-0.001992053	normal	0.385602406	-0.290006	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K16659|0|pps:100990029|RTN4R; reticulon 4 receptor; K16659 reticulon-4 receptor (A)	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat	Reticulon-4 receptor (Precursor) GN=RTN4R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: reticulon-4 receptor [Eptesicus fuscus]
ENSG00000040633(PHF23)	--	35.19524601	1324	33.938228	1398	32.02062737	1283	29.7968717	1140	36.92430173	1308	29.52142078	1074	0.945200662	-0.246393057	normal	0.977580626	-0.117297166	normal	0.934467729	-0.264477415	normal	0.266162021	-0.206794661	normal	--	--	--	--	--	--	--	PHD-finger	PHD finger protein 23 GN=PHF23 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: PHD finger protein 23 isoform 1 [Ceratotherium simum simum]
ENSG00000040731(CDH10)	--	0	0	0.0155839	1	0.0309004	1	0.123475	8	0.194844	12	0.245305	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06802|0|ptr:461942|CDH10; cadherin 10, type 2 (T2-cadherin); K06802 cadherin 10, type 2, T2-cadherin (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin-like	Cadherin-10 (Precursor) GN=CDH10 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cadherin-10-like [Panthera tigris altaica]
ENSG00000040933(INPP4A)	--	9.837626053	1030	8.27797471	939	8.623320206	980	5.796464459	642	5.736161659	588	6.6477175	667	0.005761696	-0.711473502	normal	0.011485097	-0.695306755	normal	0.14058578	-0.562327926	normal	2.20E-05	-0.657611014	normal	--	--	--	"K01109|0|hsa:3631|INPP4A, INPP4, TVAS1; inositol polyphosphate-4-phosphatase, type I, 107kDa (EC:3.1.3.66); K01109 inositol polyphosphate-4-phosphatase [EC:3.1.3.66] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	--	"Type I inositol 3,4-bisphosphate 4-phosphatase GN=INPP4A OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: type I inositol 3,4-bisphosphate 4-phosphatase isoform X4 [Canis lupus familiaris]"
ENSG00000041353(RAB27B)	--	18.41658137	1994	17.96623773	1915	21.02872172	2208	29.66925692	3232	30.54625295	3302	26.83778436	2902	0.012524801	0.665523165	normal	0.00108204	0.764104262	normal	0.817059338	0.38578474	normal	1.82E-05	0.604113798	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07886|2.1586e-162|hsa:5874|RAB27B, C25KG; RAB27B, member RAS oncogene family; K07886 Ras-related protein Rab-27B (A)"	Pancreatic secretion (ko04972)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-27B GN=RAB27B OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-27B isoform 1 [Ceratotherium simum simum] 
ENSG00000041357(PSMA4)	--	245.630132	3974	248.1498118	4104	248.9145406	3928	296.5181641	4463	283.3919151	4298	257.2013298	3878	0.988969002	0.13653984	normal	0.991886898	0.045191921	normal	0.991882016	-0.026763198	normal	0.839879173	0.052476452	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: endopeptidase activity (GO:0004175);; Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Cellular Component: proteasome core complex, alpha-subunit complex (GO:0019773);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; "	"K02728|3.73512e-176|ecb:100050569|PSMA4; proteasome (prosome, macropain) subunit, alpha type, 4; K02728 20S proteasome subunit alpha 3 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome subunit A N-terminal signature	Proteasome subunit alpha type-4 GN=PSMA4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit alpha type-4 isoform 1 [Ceratotherium simum simum] 
ENSG00000041515(MYO16)	--	0.03761825	5	0.044635544	6	0.0952944	12	0.022628788	3	0.135111579	13	0.10442911	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K17481|0|hsa:23026|MYO16, MYAP3, MYR8, Myo16b, NYAP3, PPP1R107; myosin XVI; K17481 myosin XVI (A)"	--	--	--	Myosin head (motor domain);; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Unconventional myosin-XVI OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: unconventional myosin-XVI [Myotis davidii]
ENSG00000041802(LSG1)	--	12.61141149	981	13.63471775	1074	13.41242632	1048	14.032541	1109	14.101526	1103	13.17221956	1036	0.970701986	0.145887078	normal	0.979976797	0.016988635	normal	0.979865351	-0.02487006	normal	0.875136822	0.04452795	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	K14539|0|hsa:55341|LSG1; large 60S subunit nuclear export GTPase 1; K14539 large subunit GTPase 1 [EC:3.6.1.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	50S ribosome-binding GTPase;; Ferrous iron transport protein B	Large subunit GTPase 1 homolog GN=LSG1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: large subunit GTPase 1 homolog [Galeopterus variegatus]
ENSG00000041880(PARP3)	--	6.069249	290	6.587649	326	5.667053005	308	5.798016	271	5.086677816	258	4.495614668	243	0.959962159	-0.127891178	normal	0.844881853	-0.357060842	normal	0.858698651	-0.348335262	normal	0.313571185	-0.280831675	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; Biological Process: protein ADP-ribosylation (GO:0006471);; 	"K10798|0|hsa:10039|PARP3, ADPRT3, ADPRTL2, ADPRTL3, ARTD3, IRT1, PADPRT-3; poly (ADP-ribose) polymerase family, member 3 (EC:2.4.2.30); K10798 poly [ADP-ribose] polymerase [EC:2.4.2.30] (A)"	Base excision repair (ko03410)	[KLO]	"Transcription;; Replication, recombination and repair;; Posttranslational modification, protein turnover, chaperones"	"Poly(ADP-ribose) polymerase catalytic domain;; Poly(ADP-ribose) polymerase, regulatory domain;; WGR domain"	Poly [ADP-ribose] polymerase 3 GN=PARP3 OS=Homo sapiens (Human) PE=1 SV=3	KLO	"Transcription;; Replication, recombination and repair;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: poly [ADP-ribose] polymerase 3 [Galeopterus variegatus]
ENSG00000041982(TNC)	--	0.826807264	151	0.586615533	92	1.51726543	178	8.212230541	1411	8.994940239	1489	1.444412251	264	0	3.180401702	up	0	3.973266048	up	0.428180231	0.556463123	normal	0.032041459	2.88646314	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06252|0|hsa:3371|TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C; tenascin C; K06252 tenascin (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; MicroRNAs in cancer (ko05206)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Fibronectin type III domain;; Fibrinogen beta and gamma chains, C-terminal globular domain;; EGF-like domain;; Human growth factor-like EGF;; EGF-like domain;; Interferon-alpha/beta receptor, fibronectin type III"	Tenascin (Precursor) GN=TNC OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: tenascin isoform X6 [Tupaia chinensis]
ENSG00000041988(THAP3)	--	5.589038415	145	5.061920102	133	5.5387543	155	4.787936149	125	4.406882146	107	4.45064811	116	0.946701415	-0.242189943	normal	0.921556486	-0.331036355	normal	0.853758336	-0.421662337	normal	0.39790268	-0.336543454	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 3 GN=THAP3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: THAP domain-containing protein 3 [Tupaia chinensis]
ENSG00000042062(FAM65C)	--	0.042673394	4	0	0	0.010225059	0	0.010670793	1	0.051721308	4	0.01054444	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM65C GN=FAM65C OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: protein FAM65C [Galeopterus variegatus]
ENSG00000042088(TDP1)	--	7.650115146	302	8.377490026	327	6.90011271	322	8.811337343	375	8.383577533	335	6.554666486	288	0.910030043	0.280228403	normal	0.967373401	0.013382755	normal	0.953506013	-0.168446335	normal	0.90395939	0.047641621	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: DNA repair (GO:0006281);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; 	K10862|0|hsa:55775|TDP1; tyrosyl-DNA phosphodiesterase 1 (EC:3.1.4.-); K10862 tyrosyl-DNA phosphodiesterase 1 [EC:3.1.4.-] (A)	--	[L]	"Replication, recombination and repair"	Tyrosyl-DNA phosphodiesterase	Tyrosyl-DNA phosphodiesterase 1 GN=TDP1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: tyrosyl-DNA phosphodiesterase 1 [Galeopterus variegatus]
ENSG00000042286(AIFM2)	--	33.8019779	2677	34.11026003	2663	32.10125521	2571	31.3889083	2373	31.90658218	2476	34.86470829	2706	0.974508152	-0.20461247	normal	0.984647701	-0.126393211	normal	0.988282889	0.065503228	normal	0.703841997	-0.087287526	normal	[C]	Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[R]	General function prediction only	Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD dependent oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; L-lysine 6-monooxygenase (NADPH-requiring);; Lycopene cyclase protein;; FAD-NAD(P)-binding;; Glucose inhibited division protein A;; NAD(P)-binding Rossmann-like domain;; FAD binding domain;; Tryptophan halogenase	Apoptosis-inducing factor 2 GN=AIFM2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: apoptosis-inducing factor 2 [Tupaia chinensis]
ENSG00000042304(C2orf83)	--	0	0	0.034811362	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	--	--	[H]	Coenzyme transport and metabolism	Reduced folate carrier	Folate transporter-like protein C2orf83 GN=C2orf83 OS=Homo sapiens (Human) PE=2 SV=1	H	Coenzyme transport and metabolism	hypothetical protein PANDA_008416 [Ailuropoda melanoleuca]
ENSG00000042317(SPATA7)	--	2.211726	81	3.407486	119	3.85702	135	4.7110428	168	4.730346	146	3.497962	128	0.005484854	1.008086362	up	0.938168677	0.270472587	normal	0.966547853	-0.084138941	normal	0.327210145	0.378353734	normal	--	--	--	--	--	--	--	Hydroxy-steroid dehydrogenase	Spermatogenesis-associated protein 7 GN=SPATA7 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: spermatogenesis-associated protein 7 isoform X3 [Tupaia chinensis]
ENSG00000042429(MED17)	--	22.4662713	888	24.18353417	955	19.41274387	783	17.72638401	773	18.7918875	843	22.11172615	887	0.943754929	-0.230495638	normal	0.955910374	-0.201055523	normal	0.96265678	0.17131929	normal	0.721653269	-0.090267203	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	"K15133|0|ptr:451486|MED17, CRSP6; mediator complex subunit 17; K15133 mediator of RNA polymerase II transcription subunit 17 (A)"	Thyroid hormone signaling pathway (ko04919)	[KT]	Transcription;; Signal transduction mechanisms	Subunit 17 of Mediator complex	Mediator of RNA polymerase II transcription subunit 17 GN=MED17 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 17 [Eptesicus fuscus]
ENSG00000042445(RETSAT)	--	23.8783599	1315	21.74334037	1250	20.75954315	1187	32.75203638	1860	30.11932839	1688	36.221209	2034	0.475601941	0.468944842	normal	0.715409359	0.411530363	normal	0.000786462	0.767952024	normal	0.00012951	0.552028431	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; Molecular Function: FAD binding (GO:0071949);; 	"K09516|0|hsa:54884|RETSAT; retinol saturase (all-trans-retinol 13,14-reductase) (EC:1.3.99.23); K09516 all-trans-retinol 13,14-reductase [EC:1.3.99.23] (A)"	Retinol metabolism (ko00830)	[H]	Coenzyme transport and metabolism	NAD(P)-binding Rossmann-like domain;; FAD binding domain;; Flavin containing amine oxidoreductase;; FAD dependent oxidoreductase;; Thi4 family;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase;; GDP dissociation inhibitor	"All-trans-retinol 13,14-reductase (Precursor) GN=RETSAT OS=Homo sapiens (Human) PE=1 SV=2"	H	Coenzyme transport and metabolism	"PREDICTED: all-trans-retinol 13,14-reductase [Oryctolagus cuniculus]"
ENSG00000042493(CAPG)	--	33.29215431	722	22.62035432	516	26.07927379	639	35.54317715	810	39.51559146	881	27.56947646	543	0.967846287	0.134819849	normal	0.003719547	0.748646352	normal	0.932832302	-0.242531781	normal	0.594797871	0.229183085	normal	--	--	--	"K10368|0|hsa:822|CAPG, AFCP, HEL-S-66, MCP; capping protein (actin filament), gelsolin-like; K10368 capping protein (actin filament), gelsolin-like (A)"	--	[Z]	Cytoskeleton	Gelsolin repeat	Macrophage-capping protein GN=CAPG OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: macrophage-capping protein isoform 1 [Odobenus rosmarus divergens]
ENSG00000042753(AP2S1)	--	179.28086	2274	189.44065	2413	186.31894	2399	178.813919	2351	188.649153	2331	178.568174	2316	0.988095846	0.017198593	normal	0.986835201	-0.071260026	normal	0.98749551	-0.059051458	normal	0.88635226	-0.039230051	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K11827|8.12915e-101|ptr:456156|AP2S1; adaptor-related protein complex 2, sigma 1 subunit; K11827 AP-2 complex subunit sigma-1 (A)"	Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	AP-2 complex subunit sigma GN=AP2S1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-2 complex subunit sigma [Pantholops hodgsonii]
ENSG00000042781(USH2A)	--	0.00550054	2	0	0	0.0165167	5	0.00275978	1	0.0106739	3	0.00273444	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	"Fibronectin type III domain;; Laminin EGF-like (Domains III and V);; Laminin G domain;; Laminin G domain;; Laminin N-terminal (Domain VI);; Concanavalin A-like lectin/glucanases superfamily;; Chitinase A, N-terminal domain"	Usherin (Precursor) GN=USH2A OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: usherin [Ceratotherium simum simum]
ENSG00000042832(TG)	--	0.213473811	7	0.01626231	2	0.013278653	1	0.253119378	12	0.1239254	9	0.054994919	9	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	--	"K10809|0|hsa:7038|TG, AITD3, TGN; thyroglobulin; K10809 thyroglobulin (A)"	Thyroid hormone synthesis (ko04918);; Autoimmune thyroid disease (ko05320)	--	--	Thyroglobulin type-1 repeat;; Carboxylesterase family;; GCC2 and GCC3	Thyroglobulin (Precursor) GN=TG OS=Homo sapiens (Human) PE=1 SV=5	R	General function prediction only	PREDICTED: thyroglobulin [Galeopterus variegatus]
ENSG00000042980(ADAM28)	--	0.053872255	6	0.077806092	7	0.122490746	3	0.4278616	30	1.313660463	68	0.791942482	58	0.068156565	2.038123729	normal	5.82E-09	3.010359876	up	8.63E-10	3.714460353	up	2.44E-05	3.264878148	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08614|0|hsa:10863|ADAM28, ADAM_28, ADAM23, MDC-L, MDC-Lm, MDC-Ls, MDCL, eMDC_II, eMDCII; ADAM metallopeptidase domain 28; K08614 disintegrin and metalloproteinase domain-containing protein 28 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; ADAM cysteine-rich;; Disintegrin;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 28 (Precursor) GN=ADAM28 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 28 [Ceratotherium simum simum]
ENSG00000043093(DCUN1D1)	--	13.49075097	753	16.78351276	895	17.27648199	894	15.38256034	892	12.49614069	694	15.62463447	791	0.950386696	0.213161613	normal	0.758287189	-0.387632545	normal	0.95967706	-0.184556454	normal	0.622401689	-0.118376246	normal	--	--	--	K17822|0|mcf:101866996|uncharacterized LOC101866996; K17822 DCN1-like protein 1/2 (A)	--	[S]	Function unknown	Cullin binding;; UBA-like domain	DCN1-like protein 1 GN=DCUN1D1 OS=Homo sapiens (Human) PE=1 SV=1	EI	Amino acid transport and metabolism;; Lipid transport and metabolism	PREDICTED: DCN1-like protein 1 isoform X2 [Physeter catodon]
ENSG00000043143(JADE2)	--	12.083875	1368	12.67377577	1609	12.59192672	1344	14.03401063	1751	13.5567076	1712	18.188851	2402	0.890896252	0.324955326	normal	0.983330569	0.068029826	normal	0.000115531	0.828704438	normal	0.148606514	0.420291042	normal	--	--	--	--	--	[R]	General function prediction only	PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; Enhancer of polycomb-like;; PHD-finger;; PHD-finger	Protein Jade-2 GN=JADE2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein Jade-2 [Galeopterus variegatus]
ENSG00000043355(ZIC2)	--	6.74668	285	5.72826	244	6.90461	296	7.5311	320	7.51519	318	7.45439	320	0.959058278	0.135587666	normal	0.845503054	0.358766318	normal	0.963122249	0.103673752	normal	0.522872308	0.194680154	normal	[R]	General function prediction only	--	K06235|0|mcf:102119934|ZIC2; Zic family member 2; K06235 zinc finger protein ZIC 2 (A)	Hedgehog signaling pathway (ko04340)	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein ZIC 2 GN=ZIC2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein ZIC 2 [Elephantulus edwardii]
ENSG00000043514(TRIT1)	--	7.812421185	298	6.717460182	263	6.242880002	240	7.922642225	305	8.622730018	333	7.644141781	297	0.967824291	0.002651138	normal	0.884904458	0.317407586	normal	0.904014786	0.297449245	normal	0.508496215	0.201708299	normal	--	--	Molecular Function: dimethylallyltranstransferase activity (GO:0004161);; Biological Process: tRNA processing (GO:0008033);; Biological Process: biosynthetic process (GO:0009058);; 	"K00791|0|hsa:54802|TRIT1, IPT, MOD5; tRNA isopentenyltransferase 1 (EC:2.5.1.75); K00791 tRNA dimethylallyltransferase [EC:2.5.1.75] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	IPP transferase;; AAA domain;; AAA domain;; Isopentenyl transferase;; Zinc-finger double-stranded RNA-binding	"tRNA dimethylallyltransferase, mitochondrial (Precursor) GN=TRIT1 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tRNA dimethylallyltransferase, mitochondrial [Galeopterus variegatus]"
ENSG00000043591(ADRB1)	--	0.452481	19	1.18852	51	1.32652	57	0.752802	32	0.756693	32	0.961704	41	0.954073675	0.67856999	normal	0.886463405	-0.668599474	normal	0.942754085	-0.468896543	normal	0.748052226	-0.294130615	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04141|0|hsa:153|ADRB1, ADRB1R, B1AR, BETA1AR, RHR; adrenoceptor beta 1; K04141 adrenergic receptor beta-1 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Endocytosis (ko04144);; Adrenergic signaling in cardiomyocytes (ko04261);; Gap junction (ko04540);; Salivary secretion (ko04970);; Dilated cardiomyopathy (ko05414)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx;; Serpentine type 7TM GPCR chemoreceptor Srv	Beta-1 adrenergic receptor GN=ADRB1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: beta-1 adrenergic receptor [Odobenus rosmarus divergens]
ENSG00000044090(CUL7)	--	6.996065	850	7.021708	870	6.612009	830	4.43143	536	5.195191	622	5.406827	653	0.010706084	-0.694466055	normal	0.351170789	-0.504484996	normal	0.823188186	-0.353591629	normal	0.001927603	-0.514348619	normal	--	--	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	"K10613|0|hsa:9820|CUL7, 3M1, KIAA0076, dJ20C7.5; cullin 7; K10613 cullin 7 (A)"	Ubiquitin mediated proteolysis (ko04120)	--	--	"Cullin family;; Mouse development and cellular proliferation protein Cullin-7;; Anaphase-promoting complex, subunit 10 (APC10)"	Cullin-7 GN=CUL7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cullin-7 isoform X1 [Loxodonta africana]
ENSG00000044115(CTNNA1)	--	88.75367487	6934	91.02632933	7191	88.94923825	6883	117.2788326	9146	115.5669919	8853	105.2731766	8039	0.926559066	0.368549522	normal	0.977553439	0.278494588	normal	0.987334494	0.215643217	normal	0.10904378	0.288066847	normal	--	--	Biological Process: cell adhesion (GO:0007155);; Molecular Function: actin filament binding (GO:0051015);; 	"K05691|0|ptr:450165|CTNNA1; catenin (cadherin-associated protein), alpha 1, 102kDa; K05691 catenin alpha (A)"	Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Bacterial invasion of epithelial cells (ko05100);; Pathways in cancer (ko05200);; Endometrial cancer (ko05213);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[W]	Extracellular structures	Vinculin family	Catenin alpha-1 GN=CTNNA1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: catenin alpha-1 isoform X3 [Panthera tigris altaica]
ENSG00000044446(PHKA2)	--	8.12032826	990	6.914556055	876	6.805429293	850	6.200130701	783	7.05932805	879	7.571976096	959	0.795570667	-0.368603505	normal	0.97742818	-0.016465885	normal	0.965139437	0.165499169	normal	0.784356661	-0.072068369	normal	--	--	--	"K07190|0|hsa:5256|PHKA2, GSD9A, PHK, PYK, PYKL, XLG, XLG2; phosphorylase kinase, alpha 2 (liver) (EC:2.7.11.19); K07190 phosphorylase kinase alpha/beta subunit (A)"	Calcium signaling pathway (ko04020);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 15	"Phosphorylase b kinase regulatory subunit alpha, liver isoform GN=PHKA2 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: phosphorylase b kinase regulatory subunit alpha, liver isoform isoform X1 [Physeter catodon]"
ENSG00000044459(CNTLN)	--	5.013640965	472	5.875031	580	5.042708801	489	5.070080198	543	5.1528228	536	4.834316609	509	0.955859424	0.170814383	normal	0.963200582	-0.134880497	normal	0.970735458	0.049390029	normal	0.956592571	0.021799584	normal	--	--	--	"K16467|0|pps:100975922|CNTLN; centlein, centrosomal protein; K16467 centlein (A)"	--	--	--	--	Centlein GN=CNTLN OS=Homo sapiens (Human) PE=2 SV=5	S	Function unknown	PREDICTED: centlein isoform 1 [Ceratotherium simum simum]
ENSG00000044524(EPHA3)	--	0	0	0	0	0	0	0.00997416	1	0.015703197	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05104|0|hsa:2042|EPHA3, EK4, ETK, ETK1, HEK, HEK4, TYRO4; EPH receptor A3 (EC:2.7.10.1); K05104 Eph receptor A3 [EC:2.7.10.1] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; GCC2 and GCC3	Ephrin type-A receptor 3 (Precursor) GN=EPHA3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 3 isoform X1 [Mustela putorius furo] 
ENSG00000044574(HSPA5)	--	202.1305517	15776	183.680295	14450	193.472656	14993	202.427108	15897	197.773348	15313	199.45727	15517	0.997447072	-0.019807265	normal	0.996959213	0.062254572	normal	0.997258155	0.04126504	normal	0.939370018	0.026059837	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	"K09490|0|ptr:464733|HSPA5; heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa); K09490 heat shock 70kDa protein 5 (A)"	Protein export (ko03060);; Protein processing in endoplasmic reticulum (ko04141);; Antigen processing and presentation (ko04612);; Thyroid hormone synthesis (ko04918);; Prion diseases (ko05020)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein;; MreB/Mbl protein;; Hydantoinase/oxoprolinase	78 kDa glucose-regulated protein (Precursor) GN=HSPA5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 78 kDa glucose-regulated protein [Oryctolagus cuniculus]
ENSG00000046604(DSG2)	--	35.20312374	3886	34.93616936	3835	36.61501476	3933	56.9258624	6217	49.0774	5364	48.18433053	5279	0.025447841	0.64689651	normal	0.64953624	0.462501232	normal	0.794597032	0.416204424	normal	0.000603588	0.511086819	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K07597|0|hsa:1829|DSG2, ARVC10, ARVD10, CDHF5, CMD1BB, HDGC; desmoglein 2; K07597 desmoglein 2 (A)"	Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Desmoglein-2 (Precursor) GN=DSG2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: desmoglein-2 [Tupaia chinensis]
ENSG00000046647(GEMIN8)	--	7.816075403	164	4.976511005	103	6.736559891	141	7.793183977	154	7.285720214	146	6.503324298	141	0.962636277	-0.120433087	normal	0.805540163	0.476000847	normal	0.968149087	-0.008203457	normal	0.867669608	0.090942458	normal	--	--	Biological Process: spliceosomal snRNP assembly (GO:0000387);; Cellular Component: SMN complex (GO:0032797);; 	"K13136|4.00214e-169|hsa:54960|GEMIN8, FAM51A1; gem (nuclear organelle) associated protein 8; K13136 gem associated protein 8 (A)"	RNA transport (ko03013)	--	--	Gemini of Cajal bodies-associated protein 8	Gem-associated protein 8 GN=GEMIN8 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: gem-associated protein 8 isoform X1 [Galeopterus variegatus] 
ENSG00000046651(OFD1)	--	6.857135149	532	7.384975027	568	7.514996824	571	6.276196452	493	6.492274216	506	7.25743823	574	0.961974909	-0.140249946	normal	0.951773622	-0.187650403	normal	0.973250058	-0.000729524	normal	0.697364021	-0.107877872	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16480|0|hsa:8481|OFD1, 71-7A, CXorf5, JBTS10, RP23, SGBS2; oral-facial-digital syndrome 1; K16480 oral-facial-digital syndrome 1 protein (A)"	--	--	--	--	Oral-facial-digital syndrome 1 protein GN=OFD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: oral-facial-digital syndrome 1 protein isoform X1 [Ailuropoda melanoleuca]
ENSG00000046653(GPM6B)	--	0.377839086	22	0.538479647	30	0.364741999	20	0.221573757	13	0.497386425	29	0.491121243	27	0.971576593	-0.723417713	normal	0.983898751	-0.0669056	normal	0.980718037	0.398642727	normal	0.957433693	-0.08104921	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[X]	--	Myelin proteolipid protein (PLP or lipophilin)	Neuronal membrane glycoprotein M6-b GN=GPM6B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: neuronal membrane glycoprotein M6-b isoformX3 [Equus caballus] 
ENSG00000046774(MAGEC2)	--	0.0304022	1	0	0	0	0	0	0	0.118303	3	0.0302186	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen C2 GN=MAGEC2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: melanoma-associated antigen C2-like [Galeopterus variegatus]
ENSG00000046889(PREX2)	--	0	0	0	0	0	0	0.0107799	2	0.0262658	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K17588|0|hsa:80243|PREX2, 6230420N16Rik, DEP.2, DEPDC2, P-REX2, PPP1R129; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2; K17588 phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein (A)"	--	--	--	"RhoGEF domain;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; PDZ domain (Also known as DHR or GLGF)"	"Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein GN=PREX2 OS=Homo sapiens (Human) PE=2 SV=1"	T	Signal transduction mechanisms	"PREDICTED: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein [Oryctolagus cuniculus]"
ENSG00000047056(WDR37)	--	3.68637532	297	3.941526112	289	4.2639988	322	4.889564677	414	5.3059412	415	4.551719943	385	0.642083485	0.44637198	normal	0.486353567	0.498427976	normal	0.927648861	0.248437927	normal	0.08267702	0.397796759	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 37 GN=WDR37 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 37 [Ceratotherium simum simum]
ENSG00000047188(YTHDC2)	--	10.88225595	1170	12.67787788	1360	11.37062193	1206	11.21711658	1216	11.68341784	1252	12.12480746	1309	0.981349495	0.024770529	normal	0.974477327	-0.140635598	normal	0.977724555	0.109811545	normal	0.988440292	-0.005333506	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[A]	RNA processing and modification	YT521-B-like domain;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; R3H domain;; Oligonucleotide/oligosaccharide-binding (OB)-fold;; DEAD/DEAH box helicase;; Ankyrin repeats (3 copies);; Ankyrin repeat	Probable ATP-dependent RNA helicase YTHDC2 GN=YTHDC2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase YTHDC2 [Ceratotherium simum simum]
ENSG00000047230(CTPS2)	--	9.251362207	618	9.853699	655	10.18327053	665	11.48053355	759	10.936067	724	10.46830119	692	0.92168298	0.265065327	normal	0.967600614	0.122798485	normal	0.97411501	0.049016976	normal	0.542842435	0.145045765	normal	[F]	Nucleotide transport and metabolism	Molecular Function: CTP synthase activity (GO:0003883);; Biological Process: pyrimidine nucleotide biosynthetic process (GO:0006221);; Biological Process: glutamine metabolic process (GO:0006541);; Molecular Function: hydrolase activity (GO:0016787);; 	K01937|0|hsa:56474|CTPS2; CTP synthase 2 (EC:6.3.4.2); K01937 CTP synthase [EC:6.3.4.2] (A)	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	CTP synthase N-terminus;; Glutamine amidotransferase class-I;; Peptidase C26	CTP synthase 2 GN=CTPS2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: CTP synthase 2 [Pteropus alecto]
ENSG00000047249(ATP6V1H)	--	22.15756405	759	28.018107	962	25.26818211	851	27.91676	950	25.322751	832	31.37003	1051	0.904811798	0.29246529	normal	0.945459304	-0.230489903	normal	0.904922678	0.295766411	normal	0.638491146	0.118423839	normal	[C]	Energy production and conversion	"Cellular Component: vacuolar proton-transporting V-type ATPase, V1 domain (GO:0000221);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Molecular Function: hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances (GO:0016820);; "	"K02144|0|pps:100971939|ATP6V1H; ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H; K02144 V-type H+-transporting ATPase subunit H (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Tuberculosis (ko05152);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	V-ATPase subunit H;; V-ATPase subunit H;; Armadillo/beta-catenin-like repeat;; Armadillo-like	V-type proton ATPase subunit H GN=ATP6V1H OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit H isoform X1 [Tupaia chinensis]
ENSG00000047315(POLR2B)	--	40.976878	2697	42.05263609	2806	41.11116	2661	36.682778	2566	40.357394	2686	38.284706	2537	0.986709452	-0.102606677	normal	0.987667688	-0.084435745	normal	0.987757741	-0.077091558	normal	0.696661854	-0.0890989	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K03010|0|rno:289561|Polr2b; polymerase (RNA) II (DNA directed) polypeptide B (EC:2.7.7.6); K03010 DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	"RNA polymerase Rpb2, domain 6;; RNA polymerase beta subunit;; RNA polymerase Rpb2, domain 2;; RNA polymerase Rpb2, domain 7;; RNA polymerase Rpb2, domain 4;; RNA polymerase Rpb2, domain 3;; RNA polymerase Rpb2, domain 5"	DNA-directed RNA polymerase II subunit RPB2 GN=POLR2B OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase II subunit RPB2 [Ochotona princeps]
ENSG00000047346(FAM214A)	--	5.03067596	314	6.2492726	469	5.267522564	351	9.873007892	548	7.639869656	470	10.56809305	732	0.004565858	0.76969435	normal	0.970259622	-0.018294796	normal	1.13E-06	1.048882475	up	0.1110129	0.605290456	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF4210);; Chromosome segregation during meiosis	Protein FAM214A GN=FAM214A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM214A isoform X1 [Tupaia chinensis]
ENSG00000047365(ARAP2)	--	0.912773177	51	1.614123708	63	0.362662669	48	1.161978071	162	1.207484489	169	1.08379074	133	2.82E-07	1.607984525	up	1.20E-05	1.381149403	up	3.94E-05	1.433761234	up	3.08E-06	1.49609774	up	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K18440|0|hsa:116984|ARAP2, CENTD1, PARX; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2; K18440 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 (A)"	Endocytosis (ko04144)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	RhoGAP domain;; PH domain;; Putative GTPase activating protein for Arf;; Pleckstrin homology domain;; SAM domain (Sterile alpha motif);; Pleckstrin homology domain;; SAM domain (Sterile alpha motif);; PH domain;; Ras association (RalGDS/AF-6) domain	"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 GN=ARAP2 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 [Tupaia chinensis]"
ENSG00000047410(TPR)	--	25.71056114	5373	25.71353171	5529	26.57845	5551	23.32930848	5201	25.986355	5383	24.68558784	5162	0.992884671	-0.077748464	normal	0.993175912	-0.060018066	normal	0.99186057	-0.11307704	normal	0.725950078	-0.084526787	normal	--	--	Biological Process: protein import into nucleus (GO:0006606);; 	"K09291|0|hsa:7175|TPR; translocated promoter region, nuclear basket protein; K09291 nucleoprotein TPR (A)"	RNA transport (ko03013);; Pathways in cancer (ko05200);; Thyroid cancer (ko05216)	[S]	Function unknown	TPR/MLP1/MLP2-like protein	Nucleoprotein TPR GN=TPR OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: nucleoprotein TPR-like isoform X2 [Leptonychotes weddellii]
ENSG00000047457(CP)	--	21.67227701	2004	25.56599368	2302	18.57832542	1646	24.90537121	2357	30.029938	2779	60.9548245	5837	0.972236673	0.203093296	normal	0.962289786	0.250101721	normal	0	1.817025014	up	0.332467214	0.863563435	normal	--	--	Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13624|0|hsa:1356|CP, CP-2; ceruloplasmin (ferroxidase) (EC:1.16.3.1); K13624 ceruloplasmin [EC:1.16.3.1] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Multicopper oxidase;; Multicopper oxidase;; Multicopper oxidase	Ceruloplasmin (Precursor) GN=CP OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ceruloplasmin isoform X2 [Ailuropoda melanoleuca]
ENSG00000047578(KIAA0556)	--	6.811074048	1113	9.143526631	1159	8.203014732	1290	6.547162	1056	7.119201994	1127	6.96790805	1118	0.976014186	-0.106525023	normal	0.979286987	-0.061737912	normal	0.957596296	-0.214471994	normal	0.544984325	-0.130554695	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4457);; Sad1 / UNC-like C-terminal	Uncharacterized protein KIAA0556 GN=KIAA0556 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: uncharacterized protein KIAA0556 homolog [Galeopterus variegatus]
ENSG00000047579(DTNBP1)	--	6.99581276	217	5.857499	180	6.4262414	194	6.096201331	190	7.786335476	240	6.66855176	200	0.943407672	-0.220855154	normal	0.831159872	0.390759154	normal	0.966566019	0.035380268	normal	0.882115832	0.071259799	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; 	--	--	--	--	Dysbindin (Dystrobrevin binding protein 1)	Dysbindin GN=DTNBP1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: dysbindin [Pteropus alecto]
ENSG00000047597(XK)	--	1.47179	109	1.45394	107	1.02034	74	1.35419	100	1.3591	100	1.14853	85	0.964712275	-0.152909139	normal	0.965798749	-0.117321702	normal	0.96627162	0.188057686	normal	0.955665903	-0.047343749	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	XK-related protein	Membrane transport protein XK GN=XK OS=Homo sapiens (Human) PE=1 SV=5	S	Function unknown	PREDICTED: membrane transport protein XK [Ailuropoda melanoleuca] 
ENSG00000047621(C12orf4)	--	5.977891242	358	7.772037565	375	5.886172489	376	6.934180773	450	6.867667543	451	7.584001995	490	0.894558237	0.29799046	normal	0.928956898	0.243912293	normal	0.79834853	0.372441801	normal	0.183254052	0.305958007	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2362)	Uncharacterized protein C12orf4 GN=C12orf4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C12orf4 homolog isoform X1 [Tupaia chinensis] 
ENSG00000047634(SCML1)	--	8.574803774	655	8.76528935	589	10.99447637	699	10.40926365	717	10.72964565	720	11.04849863	820	0.970687098	0.099423005	normal	0.91977978	0.267680216	normal	0.946046621	0.221596936	normal	0.368539174	0.195556308	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K11464|0|ggo:101148208|SCML1; sex comb on midleg-like protein 1; K11464 sex comb on midleg-like protein 1 (A)	--	[K]	Transcription	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Sex comb on midleg-like protein 1 GN=SCML1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: sex comb on midleg-like protein 1 [Ursus maritimus]
ENSG00000047644(WWC3)	--	11.59044	1496	11.2039	1459	10.20968	1321	9.04399	1169	8.98662	1149	11.83602	1548	0.769157142	-0.386217463	normal	0.823585521	-0.365599487	normal	0.959363927	0.220250413	normal	0.51670239	-0.165978326	normal	--	--	--	--	--	--	--	--	Protein WWC3 GN=WWC3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein WWC3 [Trichechus manatus latirostris]
ENSG00000047662(FAM184B)	--	0.49918	77	0.627639	98	0.397635	62	0.427122	66	0.521288	80	0.584502	91	0.963247196	-0.247875927	normal	0.943513241	-0.308922111	normal	0.852668947	0.5344843	normal	0.985893701	-0.020841823	normal	--	--	--	--	--	--	--	--	Protein FAM184B GN=FAM184B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM184B [Ceratotherium simum simum]
ENSG00000047849(MAP4)	--	47.643621	6218	49.16668884	6651	48.41812852	6439	58.18696865	7739	55.41702243	7294	49.17572426	6674	0.972837137	0.284801099	normal	0.993271091	0.111688115	normal	0.994480271	0.043413579	normal	0.493577356	0.147320398	normal	--	--	Molecular Function: tubulin binding (GO:0015631);; 	K10431|0|ptr:460339|MAP4; microtubule-associated protein 4; K10431 microtubule-associated protein 4 (A)	--	--	--	"Tau and MAP protein, tubulin-binding repeat"	Microtubule-associated protein 4 GN=MAP4 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: microtubule-associated protein futsch isoform X5 [Equus caballus]
ENSG00000047932(GOPC)	--	20.8679615	1577	23.44560673	1779	23.20821455	1726	23.290635	1796	25.2453409	1931	23.2253449	1764	0.976335777	0.156629366	normal	0.98306732	0.09677612	normal	0.985449893	0.023106628	normal	0.692157708	0.090501288	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF)	Golgi-associated PDZ and coiled-coil motif-containing protein GN=GOPC OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	Golgi-associated PDZ and coiled-coil motif-containing protein [Pteropus alecto]
ENSG00000048028(USP28)	--	8.814039866	738	8.352782317	694	11.28325992	877	9.070078983	712	7.81806737	621	9.038008866	686	0.972854997	-0.082401165	normal	0.956145262	-0.181350926	normal	0.808141819	-0.361952153	normal	0.303687291	-0.214601165	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11849|0|ggo:101153896|USP28; ubiquitin carboxyl-terminal hydrolase 28 isoform 1; K11849 ubiquitin carboxyl-terminal hydrolase 25/28 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 28 GN=USP28 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 28 isoform 1 [Odobenus rosmarus divergens]
ENSG00000048052(HDAC9)	--	0.434572878	52	0.921791883	59	0.414853728	40	1.32658525	112	1.45582981	106	4.683149956	375	0.025507918	1.054380558	normal	0.310770462	0.808193385	normal	0	3.172962821	up	0.224814626	1.955433263	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	K11409|0|mcc:708314|histone deacetylase 9-like; K11409 histone deacetylase 9 [EC:3.5.1.98] (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain;; Glutamine rich N terminal domain of histone deacetylase 4	Histone deacetylase 9 GN=HDAC9 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 9 isoform X10 [Canis lupus familiaris]
ENSG00000048140(TSPAN17)	--	34.327344	1596	30.04177	1442	30.598365	1480	33.04288037	1520	32.0745759	1412	31.730476	1445	0.98108816	-0.101121822	normal	0.982278277	-0.051702836	normal	0.98324445	-0.04277489	normal	0.788472891	-0.067132468	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K10303|0|mcf:102146203|TSPAN17; tetraspanin 17; K10303 F-box protein 23 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-17 GN=TSPAN17 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: tetraspanin-17 isoform X2 [Pantholops hodgsonii]
ENSG00000048162(NOP16)	--	27.88316307	588	31.21955287	674	32.67562705	708	40.54578421	860	39.32987178	819	29.151743	632	0.289106697	0.516566203	normal	0.927387928	0.259160097	normal	0.959282896	-0.171727777	normal	0.385804375	0.20846198	normal	--	--	--	--	--	[S]	Function unknown	Ribosome biogenesis protein Nop16	Nucleolar protein 16 GN=NOP16 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nucleolar protein 16 isoform X2 [Myotis lucifugus]
ENSG00000048342(CC2D2A)	--	6.82507106	464	6.677584514	561	5.363705392	402	5.0079985	464	4.907989194	458	5.876142449	514	0.970587704	-0.030730507	normal	0.879641891	-0.313143668	normal	0.840552267	0.345130465	normal	0.980122653	-0.01228571	normal	--	--	--	--	--	[R]	General function prediction only	CC2D2A N-terminal C2 domain	Coiled-coil and C2 domain-containing protein 2A GN=CC2D2A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: coiled-coil and C2 domain-containing protein 2A isoform X3 [Equus przewalskii]
ENSG00000048392(RRM2B)	--	24.31512818	1678	26.27361983	1773	26.91548628	1815	24.3427311	1679	25.72198726	1636	23.59405395	1444	0.984936939	-0.029945338	normal	0.978642721	-0.137324366	normal	0.876303795	-0.337873905	normal	0.387539964	-0.167583082	normal	[F]	Nucleotide transport and metabolism	Biological Process: oxidation-reduction process (GO:0055114);; 	"K10808|0|hsa:50484|RRM2B, MTDPS8A, MTDPS8B, P53R2; ribonucleotide reductase M2 B (TP53 inducible) (EC:1.17.4.1); K10808 ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Glutathione metabolism (ko00480);; p53 signaling pathway (ko04115)	[F]	Nucleotide transport and metabolism	"Ribonucleotide reductase, small chain"	Ribonucleoside-diphosphate reductase subunit M2 B GN=RRM2B OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: ribonucleoside-diphosphate reductase subunit M2 B isoform X1 [Lipotes vexillifer]
ENSG00000048405(ZNF800)	--	7.674613034	528	7.866936912	504	7.8131509	530	9.692068644	658	9.100370045	623	8.19195393	606	0.904337703	0.285970762	normal	0.906573666	0.28361523	normal	0.953924143	0.184541218	normal	0.239991127	0.251313449	normal	--	--	--	--	--	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; C2H2 type zinc-finger (2 copies)"	Zinc finger protein 800 GN=ZNF800 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 800 isoform X2 [Panthera tigris altaica] 
ENSG00000048471(SNX29)	--	2.606942864	397	2.036750156	296	2.243202429	332	2.791818716	372	3.402622485	439	2.22025657	384	0.961835049	-0.124172065	normal	0.316528981	0.54489768	normal	0.945761525	0.200780547	normal	0.468994295	0.200356491	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K17935|0|hsa:92017|SNX29, A-388D4.1, RUNDC2A; sorting nexin 29; K17935 sorting nexin-29 (A)"	--	[T]	Signal transduction mechanisms	RUN domain;; PX domain	Sorting nexin-29 GN=SNX29 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: sorting nexin-29, partial [Canis lupus familiaris]"
ENSG00000048540(LMO3)	--	0	0	0.146618676	7	0.088675179	2	0.101439282	5	0.290274404	7	0.110390503	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	LIM domain	LIM domain only protein 3 GN=LMO3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LIM domain only protein 3 [Ovis aries]
ENSG00000048544(MRPS10)	--	18.2639	624	16.9428	577	18.3096	616	22.987	792	22.1183	754	15.5418	532	0.880930464	0.312437975	normal	0.80856973	0.363730507	normal	0.942821433	-0.219215883	normal	0.575238441	0.171433527	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02946|2.88515e-141|hsa:55173|MRPS10, MRP-S10, PNAS-122; mitochondrial ribosomal protein S10; K02946 small subunit ribosomal protein S10 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S10p/S20e	"28S ribosomal protein S10, mitochondrial GN=MRPS10 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S10, mitochondrial isoform X2 [Tupaia chinensis]"
ENSG00000048649(RSF1)	--	13.06485354	1480	13.51496395	1609	12.43862835	1427	9.980179711	1380	11.64864622	1409	8.958981359	1205	0.977183161	-0.131619625	normal	0.962736452	-0.212705446	normal	0.944324829	-0.251952694	normal	0.285472964	-0.198911522	normal	--	--	--	"K11657|0|hsa:51773|RSF1, HBXAP, RSF-1, XAP8, p325; remodeling and spacing factor 1; K11657 remodeling and spacing factor 1 (A)"	--	--	--	"WSTF, HB1, Itc1p, MBD9 motif 3;; PHD-finger;; WSTF, HB1, Itc1p, MBD9 motif 1;; WSTF, HB1, Itc1p, MBD9 motif 2"	Remodeling and spacing factor 1 GN=RSF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	remodeling and spacing factor 1 [Equus caballus]
ENSG00000048707(VPS13D)	--	4.240590984	1298	4.00678742	1241	3.964158405	1205	4.470076136	1356	4.845325276	1450	4.326113897	1305	0.982396167	0.032197244	normal	0.963122123	0.202894308	normal	0.977984248	0.106596637	normal	0.606241439	0.113571147	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Protein of unknown function (DUF1162);; N-terminal region of Chorein, a TM vesicle-mediated sorter;; UBA/TS-N domain"	Vacuolar protein sorting-associated protein 13D OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 13D [Trichechus manatus latirostris]
ENSG00000048740(CELF2)	--	0	0	0.080260924	4	0.053305247	1	0.062138881	2	0.046598264	4	0.107924205	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13207|0|asn:102385081|CELF2; CUGBP, Elav-like family member 2; K13207 CUG-BP- and ETR3-like factor (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding domain"	CUGBP Elav-like family member 2 GN=CELF2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: CUGBP Elav-like family member 2 isoform 1 [Orcinus orca] 
ENSG00000048828(FAM120A)	--	49.690216	4593	55.209703	5021	55.83011659	5063	61.77589605	5631	57.76656606	5298	57.37093423	5276	0.973132655	0.263042527	normal	0.992932241	0.056030132	normal	0.993222603	0.051145672	normal	0.579806989	0.121557473	normal	--	--	--	--	--	--	--	--	Constitutive coactivator of PPAR-gamma-like protein 1 GN=FAM120A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: constitutive coactivator of PPAR-gamma-like protein 1 isoform X2 [Lipotes vexillifer]
ENSG00000048991(R3HDM1)	--	14.27118556	1203	17.3359899	1226	17.10027757	1267	10.2352191	748	9.324543	773	9.885544156	795	0.004517184	-0.715188486	normal	0.011447553	-0.685769873	normal	0.010682823	-0.679647599	normal	2.31E-06	-0.695254749	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	R3H domain;; SUZ domain	R3H domain-containing protein 1 GN=R3HDM1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: R3H domain-containing protein 1 isoform X1 [Camelus ferus]
ENSG00000049089(COL9A2)	--	0.2211223	5	0.030088491	2	0.044349321	2	0.046776714	3	0.092477239	5	0.140328238	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08131|1.86447e-62|hsa:1298|COL9A2, DJ39G22.4, EDM2, MED, STL5; collagen, type IX, alpha 2; K08131 collagen, type IX, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	Collagen alpha-2(IX) chain (Precursor) GN=COL9A2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-2(IX) chain [Camelus dromedarius]
ENSG00000049130(KITLG)	--	9.70961516	729	10.04230306	702	9.17300094	757	11.964292	880	10.76491	734	13.1047404	931	0.938592444	0.240290983	normal	0.974372246	0.04279232	normal	0.907420718	0.28967373	normal	0.346422824	0.197061029	normal	--	--	Molecular Function: stem cell factor receptor binding (GO:0005173);; Biological Process: cell adhesion (GO:0007155);; Cellular Component: membrane (GO:0016020);; 	K05461|5.44304e-178|nle:100587810|KITLG; KIT ligand; K05461 KIT ligand (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Hematopoietic cell lineage (ko04640);; Melanogenesis (ko04916);; Pathways in cancer (ko05200)	--	--	Stem cell factor	Soluble KIT ligand (Precursor) GN=KITLG OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: kit ligand isoform X2 [Galeopterus variegatus] 
ENSG00000049167(ERCC8)	--	7.727786	267	6.59338549	233	9.223092112	294	7.251106698	282	8.348835	305	7.900006918	289	0.966468491	0.047755753	normal	0.840902389	0.364976775	normal	0.967288437	-0.03286758	normal	0.733425894	0.121038292	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10570|0|pps:100974177|ERCC8; excision repair cross-complementation group 8; K10570 DNA excision repair protein ERCC-8 (A)	Nucleotide excision repair (ko03420);; Ubiquitin mediated proteolysis (ko04120)	[KL]	"Transcription;; Replication, recombination and repair"	"WD domain, G-beta repeat"	DNA excision repair protein ERCC-8 GN=ERCC8 OS=Homo sapiens (Human) PE=1 SV=1	KL	"Transcription;; Replication, recombination and repair"	PREDICTED: DNA excision repair protein ERCC-8 isoform X2 [Galeopterus variegatus]
ENSG00000049192(ADAMTS6)	--	0.149573048	20	0.096060325	9	0.21708137	19	0.656084696	66	0.51497101	69	0.37869651	49	0.002643313	1.61950314	up	5.09E-08	2.726142925	up	0.191736926	1.292284293	normal	6.40E-05	1.917308866	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; 	"K08621|0|hsa:11174|ADAMTS6, ADAM-TS_6, ADAM-TS6, ADAMTS-6; ADAM metallopeptidase with thrombospondin type 1 motif, 6; K08621 a disintegrin and metalloproteinase with thrombospondin motifs 6 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease;; Thrombospondin type 1 domain;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; PLAC (protease and lacunin) domain;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 6 (Precursor) GN=ADAMTS6 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 6 [Ceratotherium simum simum]
ENSG00000049239(H6PD)	--	11.75960989	2026	10.22087114	1804	9.146908411	1598	8.505885355	1475	9.94886805	1725	9.6360494	1678	0.391939149	-0.488315411	normal	0.983144198	-0.085955837	normal	0.983816781	0.062126486	normal	0.371713844	-0.175176433	normal	--	--	Molecular Function: glucose-6-phosphate dehydrogenase activity (GO:0004345);; Biological Process: carbohydrate metabolic process (GO:0005975);; Biological Process: glucose metabolic process (GO:0006006);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13937|0|hsa:9563|H6PD, CORTRD1, G6PDH, GDH; hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) (EC:1.1.1.47 3.1.1.31); K13937 hexose-6-phosphate dehydrogenase [EC:1.1.1.47 3.1.1.31] (A)"	Pentose phosphate pathway (ko00030);; Carbon metabolism (ko01200)	[G]	Carbohydrate transport and metabolism	"Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase;; Glucose-6-phosphate dehydrogenase, C-terminal domain;; Glucose-6-phosphate dehydrogenase, NAD binding domain"	6-phosphogluconolactonase (Precursor) GN=H6PD OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: GDH/6PGL endoplasmic bifunctional protein [Ceratotherium simum simum]
ENSG00000049245(VAMP3)	--	50.82527	1606	54.357934	1720	45.8163223	1448	60.48826014	1969	56.99815588	1831	53.626849	1706	0.946881036	0.262931471	normal	0.98402479	0.068738088	normal	0.958789997	0.228044952	normal	0.326329167	0.183924992	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K13505|6.56684e-52|nle:100585084|VAMP3; vesicle-associated membrane protein 3; K13505 vesicle-associated membrane protein 3 (A)	SNARE interactions in vesicular transport (ko04130);; Phagosome (ko04145)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Synaptobrevin	Vesicle-associated membrane protein 3 GN=VAMP3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein 3 [Myotis brandtii]
ENSG00000049246(PER3)	--	2.31805305	255	2.435824724	258	1.861327994	193	0.583934307	64	1.036910178	100	1.173707709	138	2.38E-14	-1.99917247	down	2.10E-07	-1.375352995	down	0.716745803	-0.48768337	normal	5.42E-05	-1.244550255	down	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K02633|0|hsa:8863|PER3, GIG13; period circadian clock 3; K02633 period circadian protein (A)"	Circadian rhythm (ko04710);; Circadian entrainment (ko04713);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Period protein 2/3C-terminal region;; PAS domain;; PAS fold;; PAS fold	Period circadian protein homolog 3 GN=PER3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: period circadian protein homolog 3 [Physeter catodon]
ENSG00000049247(UTS2)	--	1.46514	34	1.48061	34	1.89611	43	0.380733	9	0.208422	4	0.678565	16	0.086689671	-1.781827195	normal	0.000730043	-2.705628804	down	0.231041932	-1.353628668	normal	0.000621649	-1.955410164	down	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; Biological Process: regulation of blood pressure (GO:0008217);; 	K05248|2.10227e-99|ptr:746007|UTS2; urotensin 2; K05248 urotensin 2 (A)	--	--	--	Urotensin II	Urotensin-2 (Precursor) GN=UTS2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: urotensin-2 [Galeopterus variegatus]
ENSG00000049249(TNFRSF9)	--	1.209217841	62	1.078015322	56	0.619628495	27	0.755953	68	1.55809525	119	0.887550611	60	0.974487926	0.100066029	normal	0.020547729	1.046227693	normal	0.25756292	1.10132119	normal	0.304909318	0.746150824	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05146|5.62025e-165|hsa:3604|TNFRSF9, 4-1BB, CD137, CDw137, ILA; tumor necrosis factor receptor superfamily, member 9; K05146 tumor necrosis factor receptor superfamily member 9 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 9 (Precursor) GN=TNFRSF9 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 9 [Canis lupus familiaris]
ENSG00000049283(EPN3)	--	0.149989285	12	0.158250009	4	0.217424916	12	0.155221117	9	0.133491698	3	0.1917244	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipid binding (GO:0005543);; 	K12471|0|hsa:55040|EPN3; epsin 3; K12471 epsin (A)	Endocytosis (ko04144)	[F]	Nucleotide transport and metabolism	ENTH domain;; Ubiquitin interaction motif;; ANTH domain	Epsin-3 GN=EPN3 OS=Homo sapiens (Human) PE=2 SV=1	F	Nucleotide transport and metabolism	PREDICTED: epsin-3 [Orycteropus afer afer]
ENSG00000049323(LTBP1)	--	15.3856003	1856	12.57424825	1556	14.25891521	1556	14.6635554	1736	17.0214781	2015	11.766655	1350	0.980665366	-0.127153157	normal	0.86581892	0.35121053	normal	0.961939386	-0.212951694	normal	0.974200785	0.016250686	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K08023|0|cjc:100404471|LTBP1; latent transforming growth factor beta binding protein 1; K08023 latent transforming growth factor beta binding protein (A)	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; TB domain;; EGF-like domain;; EGF domain	Latent-transforming growth factor beta-binding protein 1 (Precursor) GN=LTBP1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: latent-transforming growth factor beta-binding protein 1 isoform 1 [Orcinus orca]
ENSG00000049449(RCN1)	--	129.89	6113	135.1200919	6425	132.8290189	6257	144.645	6922	135.075347	6321	143.811785	6756	0.991584055	0.148441035	normal	0.994156983	-0.044959528	normal	0.993349637	0.102382963	normal	0.791452383	0.068265735	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair	Reticulocalbin-1 (Precursor) GN=RCN1 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: reticulocalbin-1 [Tupaia chinensis]
ENSG00000049540(ELN)	--	0.018210377	1	0.017365965	1	0.040986046	1	0.173333166	9	0.14868974	6	0.198654692	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Elastin (Precursor) GN=ELN OS=Homo sapiens (Human) PE=1 SV=3	--	--	PREDICTED: uncharacterized protein LOC102736304 [Leptonychotes weddellii]
ENSG00000049541(RFC2)	--	24.126877	780	19.68726	650	26.107069	864	23.28431639	766	21.21986183	673	18.20560504	602	0.975208482	-0.056848992	normal	0.973823083	0.028674665	normal	0.246741676	-0.528444966	normal	0.435292501	-0.190134127	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K10755|0|mcf:102115979|RFC2; replication factor C (activator 1) 2, 40kDa; K10755 replication factor C subunit 2/4 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430)	[L]	"Replication, recombination and repair"	"Replication factor C C-terminal domain;; ATPase family associated with various cellular activities (AAA);; DNA polymerase III, delta subunit;; AAA domain;; Rad17 cell cycle checkpoint protein;; Magnesium chelatase, subunit ChlI;; Viral (Superfamily 1) RNA helicase;; Holliday junction DNA helicase ruvB N-terminus"	Replication factor C subunit 2 GN=RFC2 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: replication factor C subunit 2 isoform X1 [Myotis brandtii] 
ENSG00000049618(ARID1B)	--	8.953363227	1241	9.838724539	1533	8.523098038	1310	7.710441133	1196	9.92429698	1481	9.988036383	1529	0.979261987	-0.084012027	normal	0.982114072	-0.071141207	normal	0.960977569	0.214500738	normal	0.95613985	0.021902783	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11653|0|ggo:101128485|ARID1B; AT-rich interactive domain-containing protein 1B; K11653 AT-rich interactive domain-containing protein 1 (A)	--	[B]	Chromatin structure and dynamics	Domain of unknown function (DUF3518);; ARID/BRIGHT DNA binding domain	AT-rich interactive domain-containing protein 1B GN=ARID1B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 1B [Odobenus rosmarus divergens]
ENSG00000049656(CLPTM1L)	--	71.20892725	3089	76.15439428	3396	75.11429298	3310	84.77660278	3666	82.67258193	3510	82.031723	3525	0.976993197	0.21613588	normal	0.990826963	0.026196539	normal	0.989823641	0.082464084	normal	0.629396888	0.1063282	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Cleft lip and palate transmembrane protein 1 (CLPTM1)	Cleft lip and palate transmembrane protein 1-like protein GN=CLPTM1L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cleft lip and palate transmembrane protein 1-like protein [Ceratotherium simum simum]
ENSG00000049759(NEDD4L)	--	12.60590745	895	14.49347125	1001	15.06889672	1052	13.12895636	1045	12.87055704	950	17.52066295	1379	0.959851313	0.192405197	normal	0.975050802	-0.096719097	normal	0.777214855	0.381715638	normal	0.606263243	0.174496913	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	"K13305|0|mdo:100022149|NEDD4L; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; K13305 E3 ubiquitin-protein ligase NEDD4-like [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; Aldosterone-regulated sodium reabsorption (ko04960)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain	E3 ubiquitin-protein ligase NEDD4-like GN=NEDD4L OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase NEDD4-like isoform X3 [Oryctolagus cuniculus]
ENSG00000049768(FOXP3)	--	0.101811027	3	0.198258861	10	0.265442973	9	0.197442944	5	0.07085803	2	0.048835078	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K10163|0|hsa:50943|FOXP3, AIID, DIETER, IPEX, PIDX, XPID; forkhead box P3; K10163 forkhead box P3 (A)"	Inflammatory bowel disease (IBD) (ko05321)	[K]	Transcription	Fork head domain	Forkhead box protein P3 GN=FOXP3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein P3 isoform X5 [Vicugna pacos]
ENSG00000049769(PPP1R3F)	--	9.2848301	188	6.194282245	200	6.394225181	183	4.96253688	126	5.186485175	127	6.5153671	223	0.440096936	-0.602087169	normal	0.238703013	-0.670181589	normal	0.924700483	0.274847971	normal	0.542945218	-0.282112436	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: starch binding (GO:2001070);; 	"K17453|0|nle:100607079|PPP1R3F; protein phosphatase 1, regulatory subunit 3F; K17453 protein phosphatase 1 regulatory subunit 3F (A)"	Insulin signaling pathway (ko04910)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Putative phosphatase regulatory subunit	Protein phosphatase 1 regulatory subunit 3F GN=PPP1R3F OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 3F [Physeter catodon]
ENSG00000049860(HEXB)	--	108.242175	3206	112.61277	3358	104.16251	3078	91.98077	2775	78.688562	2316	108.25699	3240	0.969248256	-0.238995671	normal	0.175629806	-0.557089563	normal	0.989736832	0.065677685	normal	0.243081876	-0.231763178	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K12373|0|hsa:3074|HEXB, ENC-1AS, HEL-248; hexosaminidase B (beta polypeptide) (EC:3.2.1.52); K12373 hexosaminidase [EC:3.2.1.52] (A)"	Other glycan degradation (ko00511);; Amino sugar and nucleotide sugar metabolism (ko00520);; Glycosaminoglycan degradation (ko00531);; Glycosphingolipid biosynthesis - globo series (ko00603);; Glycosphingolipid biosynthesis - ganglio series (ko00604);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolase family 20, catalytic domain;; beta-acetyl hexosaminidase like"	Beta-hexosaminidase subunit beta chain A (Precursor) GN=HEXB OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: beta-hexosaminidase subunit beta [Orycteropus afer afer]
ENSG00000049883(PTCD2)	--	8.235634775	557	6.2442356	415	9.731410901	507	8.121433949	502	8.090225275	494	6.647241897	451	0.954031181	-0.180298028	normal	0.935969717	0.229206811	normal	0.954110574	-0.176590925	normal	0.878142483	-0.052910062	normal	--	--	--	"K17711|0|ggo:101126163|PTCD2; pentatricopeptide repeat-containing protein 2, mitochondrial; K17711 pentatricopeptide repeat domain-containing protein 2 (A)"	--	--	--	Mitochondrial 28S ribosomal protein S27	"Pentatricopeptide repeat-containing protein 2, mitochondrial GN=PTCD2 OS=Homo sapiens (Human) PE=2 SV=3"	S	Function unknown	"PREDICTED: pentatricopeptide repeat-containing protein 2, mitochondrial isoform X3 [Balaenoptera acutorostrata scammoni]"
ENSG00000050030(KIAA2022)	--	0.043002261	9	0.063779131	11	0.028944445	4	0.017315569	3	0.030178441	5	0.030890579	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein KIAA2022 GN=KIAA2022 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein KIAA2022 homolog [Felis catus]
ENSG00000050130(JKAMP)	--	53.85548981	1315	54.498355	1260	55.28338101	1323	48.63896842	1181	43.68970344	1058	48.643426	1154	0.966118101	-0.185657051	normal	0.929256669	-0.273152363	normal	0.961021684	-0.205209909	normal	0.226875178	-0.221420583	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF766)	JNK1/MAPK8-associated membrane protein OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: JNK1/MAPK8-associated membrane protein isoform X1 [Leptonychotes weddellii]
ENSG00000050165(DKK3)	--	27.39340532	1215	23.28238341	1075	25.71296982	1177	24.23272834	1069	27.27640412	1219	22.13466183	975	0.956107419	-0.215236293	normal	0.969602844	0.159723798	normal	0.921817389	-0.279536399	normal	0.633300278	-0.108772372	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: negative regulation of Wnt signaling pathway (GO:0030178);; 	--	--	[T]	Signal transduction mechanisms	Dickkopf N-terminal cysteine-rich region	Dickkopf-related protein 3 (Precursor) GN=DKK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dickkopf-related protein 3 [Pteropus alecto]
ENSG00000050327(ARHGEF5)	--	0.858336554	72	0.757434727	69	0.585745075	68	1.437281467	139	2.19473141	206	1.428817409	158	0.054168891	0.904071039	normal	7.87E-08	1.536131438	up	0.000443021	1.190165679	up	4.93E-05	1.24633255	up	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	Rho guanine nucleotide exchange factor 5/35;; RhoGEF domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Rho guanine nucleotide exchange factor 5 GN=ARHGEF5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 5 [Ceratotherium simum simum]
ENSG00000050344(NFE2L3)	--	12.67120002	847	8.14117	546	11.82730027	788	9.273450062	625	10.1679	680	5.284750941	355	0.475191287	-0.468344718	normal	0.898570109	0.29447513	normal	2.49E-08	-1.155275831	down	0.385449677	-0.415999582	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09040|0|hsa:9603|NFE2L3, NRF3; nuclear factor, erythroid 2-like 3; K09040 nuclear factor erythroid 2-related factor 1/3 (A)"	--	[K]	Transcription	bZIP Maf transcription factor;; bZIP transcription factor;; Basic region leucine zipper	Nuclear factor erythroid 2-related factor 3 GN=NFE2L3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: nuclear factor erythroid 2-related factor 3 [Ceratotherium simum simum]
ENSG00000050393(MCUR1)	--	8.5738241	742	9.07895	679	10.53002	736	6.7294769	581	7.65829	600	7.277302	607	0.76173028	-0.382814877	normal	0.950699234	-0.199402818	normal	0.906528355	-0.285653329	normal	0.13772748	-0.291643847	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1640)	Mitochondrial calcium uniporter regulator 1 GN=MCUR1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitochondrial calcium uniporter regulator 1 [Eptesicus fuscus]
ENSG00000050405(LIMA1)	--	9.037946182	723	5.142455743	409	7.1047589	575	8.717044109	699	7.6779534	587	6.36911385	472	0.972840793	-0.079363912	normal	0.421068011	0.498287567	normal	0.898744218	-0.29221682	normal	0.979892882	0.020248746	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	LIM domain and actin-binding protein 1 GN=LIMA1 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: LIM domain and actin-binding protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000050426(LETMD1)	--	29.86762593	742	20.0659445	520	23.83303203	623	24.03944288	608	27.32773979	696	24.12494335	591	0.87438453	-0.31745251	normal	0.734650361	0.398145121	normal	0.970700856	-0.084155706	normal	0.978281315	-0.013506072	normal	--	--	--	--	--	--	--	--	Putative uncharacterized protein encoded by LINC00269 GN=LINC00269 OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	PREDICTED: LETM1 domain-containing protein 1 isoform X7 [Mustela putorius furo]
ENSG00000050438(SLC4A8)	--	1.353376	149	1.113302	170	1.797388	181	1.06651	129	0.988414	119	0.777501	91	0.947321065	-0.236153577	normal	0.668515085	-0.530329339	normal	0.004582312	-0.988466007	normal	0.075490963	-0.582611183	normal	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13859|0|hsa:9498|SLC4A8, NBC3, NDCBE; solute carrier family 4, sodium bicarbonate cotransporter, member 8; K13859 solute carrier family 4 (sodium bicarbonate cotransporter), member 8 (A)"	--	[P]	Inorganic ion transport and metabolism	HCO3- transporter family;; Band 3 cytoplasmic domain	Electroneutral sodium bicarbonate exchanger 1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: electroneutral sodium bicarbonate exchanger 1 isoform X1 [Galeopterus variegatus]
ENSG00000050555(LAMC3)	--	1.825896102	141	1.543996164	139	2.593193488	179	0.448325658	38	0.558404964	44	0.426405804	36	9.51E-09	-1.88014199	down	7.70E-07	-1.647323554	down	7.67E-14	-2.274751453	down	1.43E-09	-1.980499665	down	--	--	--	"K06247|0|hsa:10319|LAMC3, OCCM; laminin, gamma 3; K06247 laminin, gamma 3 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin N-terminal (Domain VI);; Laminin B (Domain IV)	Laminin subunit gamma-3 (Precursor) GN=LAMC3 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: laminin subunit gamma-3 [Tupaia chinensis]
ENSG00000050628(PTGER3)	--	0	0	0	0	0	0	0.016716887	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04260|0|ptr:456940|PTGER3; prostaglandin E receptor 3 (subtype EP3); K04260 prostaglandin E receptor 3 (A)	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srbc	Prostaglandin E2 receptor EP3 subtype GN=PTGER3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: prostaglandin E2 receptor EP3 subtype isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000050730(TNIP3)	--	0.100397472	5	0.512687216	19	0.421761039	15	0.206230691	10	0.061641745	2	0.165931248	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TNFAIP3-interacting protein 3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: TNFAIP3-interacting protein 3 [Dasypus novemcinctus]
ENSG00000050748(MAPK9)	--	22.29512674	1179	20.66400032	1067	21.47371125	1111	26.01325598	1296	26.3303026	1276	19.698996	1016	0.977821548	0.105538531	normal	0.948878336	0.236334955	normal	0.972359028	-0.137054699	normal	0.763585599	0.074159042	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K04440|0|ptr:462336|MAPK9; mitogen-activated protein kinase 9; K04440 c-Jun N-terminal kinase [EC:2.7.11.24] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Protein processing in endoplasmic reticulum (ko04141);; Wnt signaling pathway (ko04310);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Salmonella infection (ko05132);; Pertussis (ko05133);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Mitogen-activated protein kinase 9 GN=MAPK9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 9 isoform X1 [Galeopterus variegatus]
ENSG00000050767(COL23A1)	--	0	0	0.017094311	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	Collagen alpha-1(XXIII) chain GN=COL23A1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: collagen alpha-1(XXIII) chain isoform X3 [Oryctolagus cuniculus]
ENSG00000050820(BCAR1)	--	34.50430582	2218	32.80007316	2008	35.89092851	2333	40.32920282	2451	37.96843481	2294	32.41758804	2044	0.984832819	0.113204241	normal	0.977705475	0.170559318	normal	0.973242164	-0.19894467	normal	0.918772577	0.028199485	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05726|0|hsa:9564|BCAR1, CAS, CAS1, CASS1, CRKAS, P130Cas; breast cancer anti-estrogen resistance 1; K05726 breast cancer anti-estrogen resistance 1 (A)"	Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100)	--	--	Domain of unknown function (DUF3513);; Serine rich protein interaction domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Breast cancer anti-estrogen resistance protein 1 GN=BCAR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: breast cancer anti-estrogen resistance protein 1 isoform X1 [Physeter catodon]
ENSG00000051009(FAM160A2)	--	8.1911032	624	8.860468	674	8.282316362	626	7.627952	547	6.966329104	531	8.20152865	602	0.942407564	-0.220257672	normal	0.807091287	-0.364539345	normal	0.972187464	-0.064531627	normal	0.327195526	-0.216651264	normal	--	--	--	--	--	[S]	Function unknown	Retinoic acid induced 16-like protein	FTS and Hook-interacting protein GN=FAM160A2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: FTS and Hook-interacting protein isoform 1 [Ceratotherium simum simum]
ENSG00000051108(HERPUD1)	--	18.38074106	710	23.71905286	908	18.9894596	752	20.850132	819	19.63715203	693	48.9533993	1835	0.960309318	0.174859642	normal	0.696780839	-0.410478326	normal	7.15E-12	1.276985896	up	0.635229002	0.479112781	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K14027|0|pps:100984143|HERPUD1; homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1; K14027 homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin family	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein GN=HERPUD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein isoform X1 [Galeopterus variegatus]
ENSG00000051128(HOMER3)	--	16.8767759	413	16.61399166	434	16.69951244	436	30.8792325	787	29.01070198	761	28.14519	746	7.87E-05	0.896933345	normal	0.001893559	0.786679049	normal	0.002666736	0.764505032	normal	6.99E-07	0.817034233	normal	--	--	--	K15010|0|ptr:736171|HOMER3; homer homolog 3 (Drosophila); K15010 homer (A)	FoxO signaling pathway (ko04068);; Glutamatergic synapse (ko04724)	--	--	WH1 domain	Homer protein homolog 3 GN=HOMER3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: homer protein homolog 3 [Pteropus alecto]
ENSG00000051180(RAD51)	--	7.327239155	297	7.998980295	329	7.50534089	292	7.918706115	311	7.3909338	263	6.390855034	255	0.967328775	0.035440222	normal	0.860682052	-0.342685453	normal	0.945571845	-0.202638605	normal	0.59683371	-0.169106763	normal	[L]	"Replication, recombination and repair"	Molecular Function: single-stranded DNA binding (GO:0003697);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; 	"K04482|0|hsa:5888|RAD51, BRCC5, HRAD51, HsRad51, HsT16930, MRMV2, RAD51A, RECA; RAD51 recombinase; K04482 DNA repair protein RAD51 (A)"	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460);; Pathways in cancer (ko05200);; Pancreatic cancer (ko05212)	[L]	"Replication, recombination and repair"	Rad51;; Helix-hairpin-helix domain;; AAA domain;; recA bacterial DNA recombination protein	DNA repair protein RAD51 homolog 1 GN=RAD51 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein RAD51 homolog 1 isoform X2 [Camelus ferus]
ENSG00000051341(POLQ)	--	7.963769093	1344	9.02060085	1525	10.05956927	1670	6.834979647	1158	5.766872784	969	7.904212853	1333	0.946042505	-0.24542753	normal	0.013214765	-0.674820068	normal	0.879023534	-0.333124364	normal	0.035834284	-0.412189283	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication (GO:0006260);; 	"K02349|0|hsa:10721|POLQ, POLH, PRO0327; polymerase (DNA directed), theta (EC:2.7.7.7); K02349 DNA polymerase theta [EC:2.7.7.7] (A)"	--	[R]	General function prediction only	DNA polymerase family A;; DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Helix-hairpin-helix domain	DNA polymerase theta GN=POLQ OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase theta [Ceratotherium simum simum]
ENSG00000051382(PIK3CB)	--	13.42186645	781	15.76230925	768	14.33539229	788	22.24155081	938	17.53024923	831	20.71113196	897	0.943286314	0.233014385	normal	0.972797167	0.092141159	normal	0.961206652	0.17829999	normal	0.431579487	0.168679566	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; 	"K00922|0|pps:100990108|PIK3CB; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; K00922 phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153] (A)"	Inositol phosphate metabolism (ko00562);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; Carbohydrate digestion and absorption (ko04973);; Bacterial invasion of epithelial cells (ko05100);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	"Phosphoinositide 3-kinase family, accessory domain (PIK domain);; Phosphatidylinositol 3- and 4-kinase;; PI3-kinase family, p85-binding domain;; PI3-kinase family, ras-binding domain;; Phosphoinositide 3-kinase C2"	"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform GN=PIK3CB OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform [Physeter catodon]"
ENSG00000051523(CYBA)	--	318.7587395	3169	275.8655703	2906	274.2280154	2886	375.1142941	3807	353.1881681	3475	338.3695654	3390	0.973650895	0.233691164	normal	0.971387463	0.236439074	normal	0.974089807	0.223814212	normal	0.189455056	0.230466568	normal	--	--	Molecular Function: heme binding (GO:0020037);; 	"K08009|4.92916e-82|hsa:1535|CYBA, p22-PHOX; cytochrome b-245, alpha polypeptide; K08009 cytochrome b-245, alpha polypeptide (A)"	Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Leukocyte transendothelial migration (ko04670);; Leishmaniasis (ko05140)	--	--	Cytochrome Cytochrome b558 alpha-subunit	Cytochrome b-245 light chain GN=CYBA OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: cytochrome b-245 light chain-like [Myotis lucifugus]
ENSG00000051596(THOC3)	--	43.35773772	1150	39.52094136	1021	51.34418566	1331	51.36456065	1321	47.74851475	1229	48.30863099	1244	0.969404785	0.168953616	normal	0.943733398	0.245743337	normal	0.978395801	-0.105691285	normal	0.687403217	0.094548539	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K12880|0|ptr:462282|THOC3; THO complex 3; K12880 THO complex subunit 3 (A)	RNA transport (ko03013);; Spliceosome (ko03040)	[S]	Function unknown	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A;; WD40-like Beta Propeller Repeat"	THO complex subunit 3 GN=THOC3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: THO complex subunit 3 [Canis lupus familiaris] 
ENSG00000051620(HEBP2)	--	13.406694	736	13.413012	658	13.75956	759	14.802303	722	15.90332	793	14.696689	762	0.974427375	-0.058416065	normal	0.933431463	0.247288391	normal	0.976441418	-0.002595169	normal	0.836905203	0.05997329	normal	--	--	--	--	--	--	--	SOUL heme-binding protein	Heme-binding protein 2 GN=HEBP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: heme-binding protein 2 [Pantholops hodgsonii]
ENSG00000051825(MPHOSPH9)	--	9.40166498	964	9.354168991	994	10.67236687	928	9.33556287	986	8.94101744	938	8.93569987	1036	0.979253374	0.001719527	normal	0.974192496	-0.104920132	normal	0.969180289	0.150303926	normal	0.966060173	0.015357903	normal	--	--	--	"K16775|0|hsa:10198|MPHOSPH9, MPP-9, MPP9; M-phase phosphoprotein 9; K16775 M-phase phosphoprotein 9 (A)"	--	--	--	--	M-phase phosphoprotein 9 GN=MPHOSPH9 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: M-phase phosphoprotein 9 isoform X1 [Galeopterus variegatus]
ENSG00000052126(PLEKHA5)	--	5.579541934	509	4.252025085	388	5.068234917	456	9.755718131	768	8.558799906	788	6.675586866	619	0.162865217	0.561220578	normal	6.02E-06	0.997928432	normal	0.637156762	0.431381653	normal	0.000208676	0.663191866	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PH domain;; WW domain	Pleckstrin homology domain-containing family A member 5 GN=PLEKHA5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: pleckstrin homology domain-containing family A member 5 isoform X1 [Canis lupus familiaris]
ENSG00000052344(PRSS8)	--	0.035603313	1	0.115948487	3	0.224470786	2	0.254543808	8	0.718750532	9	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K08664|0|hsa:5652|PRSS8, CAP1, PROSTASIN; protease, serine, 8; K08664 protease, serine, 8 (prostasin) [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Prostasin heavy chain (Precursor) GN=PRSS8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prostasin [Ailuropoda melanoleuca] 
ENSG00000052723(SIKE1)	--	4.44235	347	6.904145	453	4.280942279	338	5.51219	391	5.151912752	415	4.975931	376	0.959100681	0.140813105	normal	0.958463806	-0.147312255	normal	0.958403058	0.144803445	normal	0.935206041	0.033117261	normal	--	--	--	K12656|7.19894e-133|ptr:457146|SIKE1; suppressor of IKBKE 1; K12656 suppressor of IKK-epsilon (A)	RIG-I-like receptor signaling pathway (ko04622)	--	--	Protein of unknown function (DUF837)	Suppressor of IKBKE 1 GN=SIKE1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: suppressor of IKBKE 1-like isoform X1 [Tupaia chinensis]
ENSG00000052749(RRP12)	--	15.72394643	1509	15.58008529	1486	15.04434239	1528	16.62520838	1644	15.2414	1511	15.90920168	1510	0.981791506	0.092694795	normal	0.983645761	0.002640322	normal	0.984014506	-0.025362185	normal	0.939818422	0.023167464	normal	--	--	--	K14794|0|ggo:101146329|RRP12; RRP12-like protein; K14794 ribosomal RNA-processing protein 12 (A)	--	[S]	Function unknown	NUC173 domain	RRP12-like protein GN=RRP12 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: RRP12-like protein [Felis catus]
ENSG00000052795(FNIP2)	--	1.789620033	200	2.016940461	257	2.165358636	209	2.63899439	336	3.104701391	396	3.565062	450	0.043561779	0.713357867	normal	0.187196818	0.599443466	normal	3.38E-06	1.092613027	up	0.000145297	0.807127917	normal	--	--	--	--	--	[S]	Function unknown	Folliculin-interacting protein middle domain;; Folliculin-interacting protein C-terminus;; Folliculin-interacting protein N-terminus	Folliculin-interacting protein 2 GN=FNIP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: folliculin-interacting protein 2 [Ceratotherium simum simum]
ENSG00000052802(MSMO1)	--	86.505445	2610	82.514897	2483	98.346244	2964	32.029033	978	30.003971	917	80.8929428	2486	6.66E-16	-1.445526743	down	1.33E-15	-1.456994146	down	0.959092954	-0.261864505	normal	0.069950191	-0.897004318	normal	[I]	Lipid transport and metabolism	Molecular Function: iron ion binding (GO:0005506);; Biological Process: lipid biosynthetic process (GO:0008610);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K07750|0|pps:100986460|MSMO1; methylsterol monooxygenase 1; K07750 methylsterol monooxygenase [EC:1.14.13.72] (A)	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	Fatty acid hydroxylase superfamily	Methylsterol monooxygenase 1 GN=MSMO1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: methylsterol monooxygenase 1 isoformX1 [Canis lupus familiaris] 
ENSG00000052841(TTC17)	--	15.39609	1219	15.72243	1299	14.777539	1144	16.471666	1259	17.985205	1420	18.93635	1640	0.981899537	0.015728387	normal	0.978555459	0.106943836	normal	0.289927255	0.510750465	normal	0.277492135	0.217496821	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 17 GN=TTC17 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 17 isoform X2 [Mustela putorius furo] 
ENSG00000052850(ALX4)	--	1.91988	221	1.16761	136	1.24999	146	1.41263	162	2.18751	250	1.33288	154	0.703119945	-0.475010359	normal	0.012039724	0.849824012	normal	0.966379418	0.067984818	normal	0.831204751	0.148931742	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K09451|0|hsa:60529|ALX4, CRS5, FND2, PFM2; ALX homeobox 4; K09451 homeobox protein aristaless-like 4 (A)"	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Homeobox protein aristaless-like 4 GN=ALX4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein aristaless-like 4 [Mustela putorius furo] 
ENSG00000053108(FSTL4)	--	4.036453305	217	2.125620974	132	4.956848113	242	3.848244644	169	4.102427269	226	3.5900864	183	0.843573318	-0.388378737	normal	0.077101909	0.747737932	normal	0.805630948	-0.408509392	normal	0.940634051	-0.052218137	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Kazal-type serine protease inhibitor domain;; Immunoglobulin V-set domain;; Kazal-type serine protease inhibitor domain	Follistatin-related protein 4 (Precursor) GN=FSTL4 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: follistatin-related protein 4 [Equus caballus]
ENSG00000053254(FOXN3)	--	6.945969295	729	5.32357259	702	6.018793823	585	9.60740324	839	10.88441197	846	10.45597157	810	0.961447457	0.171582456	normal	0.934657986	0.24727425	normal	0.514034647	0.460178579	normal	0.131728904	0.285926862	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09407|0|hsa:1112|FOXN3, C14orf116, CHES1, PRO1635; forkhead box N3; K09407 forkhead box protein N (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein N3 GN=FOXN3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein N3 isoform 1 [Ceratotherium simum simum]
ENSG00000053328(METTL24)	--	0.0599719	1	0.173615	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Methyltransferase domain;; Methyltransferase FkbM domain	Methyltransferase-like protein 24 (Precursor) GN=METTL24 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: methyltransferase-like protein 24 [Loxodonta africana]
ENSG00000053371(AKR7A2)	--	29.034149	681	25.65828	617	27.431502	671	24.34213499	583	23.896796	560	28.866224	690	0.926989632	-0.254370134	normal	0.95926642	-0.160856173	normal	0.974740518	0.031921206	normal	0.624874209	-0.123887738	normal	[C]	Energy production and conversion	--	"K15303|0|hsa:8574|AKR7A2, AFAR, AFAR1, AFB1-AR1, AKR7; aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) (EC:1.1.1.n11); K15303 aflatoxin B1 aldehyde reductase (A)"	Metabolism of xenobiotics by cytochrome P450 (ko00980)	--	--	Aldo/keto reductase family	Aflatoxin B1 aldehyde reductase member 2 GN=AKR7A2 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: aflatoxin B1 aldehyde reductase member 2 [Galeopterus variegatus]
ENSG00000053372(MRTO4)	--	24.2294	1189	24.6299	1237	26.42	1318	26.9602	1329	29.5071	1436	20.7102	1017	0.97561714	0.129601671	normal	0.965356724	0.193563899	normal	0.775046125	-0.381821935	normal	0.987369772	-0.007125662	normal	[J]	"Translation, ribosomal structure and biogenesis"	Cellular Component: intracellular (GO:0005622);; Biological Process: ribosome biogenesis (GO:0042254);; 	K14815|6.88854e-166|ptr:742881|MRTO4; mRNA turnover 4 homolog (S. cerevisiae); K14815 mRNA turnover protein 4 (A)	--	[A]	RNA processing and modification	Ribosomal protein L10	mRNA turnover protein 4 homolog {ECO:0000250|UniProtKB:P33201} GN=MRTO4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: mRNA turnover protein 4 homolog [Ailuropoda melanoleuca] 
ENSG00000053438(NNAT)	--	0.355950309	8	0.375946	8	0.366525175	7	0.287989318	6	0.650172003	13	0.424275	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Neuronatin GN=NNAT OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuronatin isoform 1 [Dasypus novemcinctus] 
ENSG00000053501(USE1)	--	8.252972693	116	7.675022486	121	8.780043251	90	8.063948386	114	9.1430395	110	9.709245661	131	0.968975268	-0.055185892	normal	0.961206981	-0.156872791	normal	0.767951298	0.525913145	normal	0.872319994	0.097252683	normal	--	--	--	K08507|0|ptr:455822|USE1; unconventional SNARE in the ER 1 homolog (S. cerevisiae); K08507 unconventional SNARE in the endoplasmic reticulum protein 1 (A)	SNARE interactions in vesicular transport (ko04130)	[S]	Function unknown	Membrane fusion protein Use1	Vesicle transport protein USE1 GN=USE1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: vesicle transport protein USE1 [Ovis aries]
ENSG00000053524(MCF2L2)	--	1.146704741	65	0.866138	49	0.89240926	50	2.015088076	115	1.8681232	107	1.9996425	115	0.320723377	0.778291184	normal	0.023538268	1.082195608	normal	0.005121215	1.169377662	up	0.006201774	1.017665045	up	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Divergent CRAL/TRIO domain	Probable guanine nucleotide exchange factor MCF2L2 GN=MCF2L2 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: probable guanine nucleotide exchange factor MCF2L2 [Equus caballus]
ENSG00000053702(NRIP2)	--	0.32679388	17	0.546354219	29	0.708823707	37	0.4697802	26	0.6194572	33	0.66629458	35	0.976622199	0.542282836	normal	0.982184629	0.157293617	normal	0.982283715	-0.084893699	normal	0.878142483	0.160096703	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Biological Process: proteolysis (GO:0006508);; 	K13215|1.19661e-178|hsa:83714|NRIP2; nuclear receptor interacting protein 2; K13215 nuclear receptor-interacting protein 2 (A)	--	[L]	"Replication, recombination and repair"	Aspartyl protease	Nuclear receptor-interacting protein 2 GN=NRIP2 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: nuclear receptor-interacting protein 2 [Ceratotherium simum simum]
ENSG00000053747(LAMA3)	--	16.83906824	3585	20.07636528	4269	17.06972448	3687	13.01909657	2594	10.70530276	2377	21.11371505	4234	0.400562474	-0.497375074	normal	4.35E-05	-0.865765618	normal	0.983283082	0.191209171	normal	0.402102147	-0.34614793	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Biological Process: cell adhesion (GO:0007155);; Biological Process: regulation of cell adhesion (GO:0030155);; Biological Process: regulation of cell migration (GO:0030334);; Biological Process: regulation of embryonic development (GO:0045995);; 	"K06240|0|ptr:455339|LAMA3; laminin, alpha 3; K06240 laminin, alpha 3/5 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin G domain;; Laminin Domain I;; Laminin N-terminal (Domain VI);; Laminin G domain;; Laminin Domain II;; Concanavalin A-like lectin/glucanases superfamily;; Laminin B (Domain IV)	Laminin subunit alpha-3 (Precursor) GN=LAMA3 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: laminin subunit alpha-3 isoform 1 [Ceratotherium simum simum]
ENSG00000053770(AP5M1)	--	15.108392	792	13.744728	788	14.77074065	820	14.468321	893	15.25214073	870	15.059963	872	0.96809509	0.142067834	normal	0.97033039	0.121171838	normal	0.975022134	0.08026921	normal	0.63570135	0.113572009	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family	AP-5 complex subunit mu-1 GN=AP5M1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-5 complex subunit mu-1 [Eptesicus fuscus]
ENSG00000053900(ANAPC4)	--	7.297704	297	8.839354	353	8.940498	374	8.157037	322	6.937678	281	6.977209547	263	0.964700826	0.085341442	normal	0.850327321	-0.348845524	normal	0.446584228	-0.513776417	normal	0.33504516	-0.263383349	normal	--	--	--	"K03351|0|hsa:29945|ANAPC4, APC4; anaphase promoting complex subunit 4; K03351 anaphase-promoting complex subunit 4 (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"Anaphase-promoting complex, cyclosome, subunit 4;; Anaphase-promoting complex subunit 4 WD40 domain"	Anaphase-promoting complex subunit 4 GN=ANAPC4 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anaphase-promoting complex subunit 4 isoform X1 [Galeopterus variegatus] 
ENSG00000053918(KCNQ1)	--	0.634825627	31	0.148694391	9	0.223453446	14	0.538181472	6	0.202278477	12	0.091935165	6	0.028154984	-2.137060161	normal	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04926|0|hsa:3784|KCNQ1, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, KVLQT1, Kv1.9, Kv7.1, LQT, LQT1, RWS, SQT2, WRS; potassium voltage-gated channel, KQT-like subfamily, member 1; K04926 potassium voltage-gated channel KQT-like subfamily member 1 (A)"	Adrenergic signaling in cardiomyocytes (ko04261);; Cholinergic synapse (ko04725);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Protein digestion and absorption (ko04974);; Vibrio cholerae infection (ko05110)	[P]	Inorganic ion transport and metabolism	KCNQ voltage-gated potassium channel;; Ion transport protein;; Ion channel	Potassium voltage-gated channel subfamily KQT member 1 GN=KCNQ1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily KQT member 1 [Orcinus orca]
ENSG00000054116(TRAPPC3)	--	37.50358209	702	40.30748601	733	35.349635	647	37.80545	741	36.325552	691	39.520243	750	0.974810258	0.047069975	normal	0.969956987	-0.106328061	normal	0.950886024	0.204389351	normal	0.881309871	0.04630582	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Transport protein particle (TRAPP) component	Trafficking protein particle complex subunit 3 GN=TRAPPC3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 3 isoform X2 [Mustela putorius furo] 
ENSG00000054118(THRAP3)	--	37.55389585	3429	37.0689734	3567	30.31323073	3077	35.05311937	3304	44.4251951	3704	33.115217	3378	0.989663668	-0.084367965	normal	0.99110826	0.032932623	normal	0.987211767	0.126294182	normal	0.940493506	0.022846637	normal	--	--	--	K13112|0|ptr:456752|THRAP3; thyroid hormone receptor associated protein 3; K13112 thyroid hormone receptor-associated protein 3 (A)	--	--	--	THRAP3/BCLAF1 family	Thyroid hormone receptor-associated protein 3 GN=THRAP3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: thyroid hormone receptor-associated protein 3 [Galeopterus variegatus] 
ENSG00000054148(PHPT1)	--	112.36566	1604	139.230322	1992	133.750982	2002	117.430208	1670	103.858376	1428	139.09416	2012	0.984722038	0.027316055	normal	0.361116712	-0.501196574	normal	0.986920321	-0.001102281	normal	0.622114561	-0.152128012	normal	--	--	--	--	--	--	--	Janus/Ocnus family (Ocnus)	14 kDa phosphohistidine phosphatase GN=PHPT1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 14 kDa phosphohistidine phosphatase [Pteropus alecto] 
ENSG00000054179(ENTPD2)	--	0.139219206	5	0.111674	4	0	0	0.247425585	6	0.135119593	4	0.040648221	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K01509|0|pps:100985560|ENTPD2; ectonucleoside triphosphate diphosphohydrolase 2; K01509 adenosinetriphosphatase [EC:3.6.1.3] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	GDA1/CD39 (nucleoside phosphatase) family	Ectonucleoside triphosphate diphosphohydrolase 2 GN=ENTPD2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	ectonucleoside triphosphate diphosphohydrolase 2 [Bos taurus] 
ENSG00000054219(LY75)	--	6.516568391	375	5.4724404	305	5.50036915	301	1.622537	93	2.4773904	146	1.8525828	106	0	-2.024365427	down	5.41E-05	-1.076373637	down	1.46E-09	-1.500704584	down	1.38E-11	-1.528463296	down	--	--	--	"K06559|0|hsa:4065|LY75, CD205, CLEC13B, DEC-205, GP200-MR6, LY-75; lymphocyte antigen 75; K06559 lymphocyte antigen 75 (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; Fibronectin type II domain;; UL45 protein;; Extracellular link domain;; Chordopoxvirus A33R protein	Lymphocyte antigen 75 (Precursor) GN=LY75 OS=Homo sapiens (Human) PE=1 SV=3	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: lymphocyte antigen 75 isoform X3 [Galeopterus variegatus]
ENSG00000054267(ARID4B)	--	9.040738829	1187	11.91540781	1539	11.7023492	1516	10.6909905	1427	11.17308011	1462	10.03405162	1328	0.951849834	0.234555939	normal	0.980679652	-0.095380302	normal	0.965356443	-0.199093682	normal	0.915984789	-0.029756059	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[BK]	Chromatin structure and dynamics;; Transcription	RBB1NT (NUC162) domain;; ARID/BRIGHT DNA binding domain;; RNA binding activity-knot of a chromodomain	AT-rich interactive domain-containing protein 4B GN=ARID4B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 4B isoform X3 [Galeopterus variegatus]
ENSG00000054277(OPN3)	--	28.5976119	1739	32.89718974	2115	33.8497577	1893	41.43181721	2565	37.68889051	2165	46.51153773	2597	0.232203214	0.529481288	normal	0.987117322	0.01227413	normal	0.599955828	0.447573664	normal	0.038040673	0.329111302	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04256|0|ptr:457854|OPN3; opsin 3; K04256 c-opsin (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Opsin-3 GN=OPN3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rab proteins geranylgeranyltransferase component A 2-like isoform 2 [Odobenus rosmarus divergens]
ENSG00000054282(SDCCAG8)	--	4.594017	233	3.790859	209	4.759889329	247	7.941115	452	6.648011	363	6.41614	355	0.000263046	0.920727213	normal	0.014558611	0.770757846	normal	0.468029619	0.512385985	normal	0.000444169	0.742160744	normal	--	--	Cellular Component: centrosome (GO:0005813);; Biological Process: centrosome cycle (GO:0007098);; 	"K16488|0|hsa:10806|SDCCAG8, BBS16, CCCAP, CCCAP_SLSN7, NPHP10, NY-CO-8, SLSN7, hCCCAP; serologically defined colon cancer antigen 8; K16488 serologically defined colon cancer antigen 8 (A)"	--	--	--	--	Serologically defined colon cancer antigen 8 GN=SDCCAG8 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: serologically defined colon cancer antigen 8 [Orcinus orca]
ENSG00000054356(PTPRN)	--	0.292353442	12	0.22949109	7	0.437252141	8	0.115743887	9	0.100061074	7	0.372813693	11	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	K07817|0|ggo:101141224|PTPRN; receptor-type tyrosine-protein phosphatase-like N isoform 1; K07817 receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48] (A)	Type I diabetes mellitus (ko04940)	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase;; Protein-tyrosine phosphatase receptor IA-2;; RESP18 domain	Receptor-type tyrosine-protein phosphatase-like N (Precursor) GN=PTPRN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: protein tyrosine phosphatase, receptor type, N isoformX1 [Sus scrofa]"
ENSG00000054392(HHAT)	--	3.270532809	183	2.969609361	180	3.180119837	186	4.705850402	243	5.344622412	275	5.250686185	288	0.848460811	0.375536611	normal	0.333455573	0.585997662	normal	0.218494395	0.618403089	normal	0.041433079	0.533365852	normal	[M]	Cell wall/membrane/envelope biogenesis	--	--	--	[T]	Signal transduction mechanisms	"MBOAT, membrane-bound O-acyltransferase family"	Protein-cysteine N-palmitoyltransferase HHAT GN=HHAT OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein-cysteine N-palmitoyltransferase HHAT [Orycteropus afer afer]
ENSG00000054523(KIF1B)	--	8.809888847	1565	8.077351604	1399	8.809074779	1500	10.76365751	1840	10.22476816	1740	8.51437092	1441	0.967798672	0.202527329	normal	0.924828808	0.292980324	normal	0.982478484	-0.066115593	normal	0.463423508	0.147799178	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10392|0|cjc:100403562|KIF1B; kinesin family member 1B; K10392 kinesin family member 1 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain;; Kinesin protein;; PH domain;; Kinesin protein 1B;; FHA domain	Kinesin-like protein KIF1B GN=KIF1B OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF1B isoform X1 [Galeopterus variegatus]
ENSG00000054598(FOXC1)	--	5.95113	349	3.89626	230	4.86359	292	4.19967	249	4.0851	242	3.25388	194	0.457335392	-0.515214062	normal	0.964879425	0.051615759	normal	0.273934763	-0.594399633	normal	0.238320253	-0.368343344	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09396|0|hsa:2296|FOXC1, ARA, FKHL7, FREAC-3, FREAC3, IGDA, IHG1, IRID1, RIEG3; forkhead box C1; K09396 forkhead box protein C (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein C1 GN=FOXC1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: forkhead box protein C1 [Erinaceus europaeus]
ENSG00000054611(TBC1D22A)	--	10.47744308	577	10.08590398	574	10.37403361	595	10.30271048	641	12.13202868	681	12.47595387	686	0.966824339	0.120615973	normal	0.941457182	0.224633619	normal	0.952077244	0.196561829	normal	0.432639805	0.180800608	normal	[R]	General function prediction only	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	TBC1 domain family member 22A GN=TBC1D22A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 22A [Ceratotherium simum simum]
ENSG00000054654(SYNE2)	--	5.191286891	2060	7.147463565	2809	6.47178364	2469	4.86367305	2029	4.602665557	2137	12.03288803	4758	0.986357285	-0.052668154	normal	0.745231675	-0.415638843	normal	2.21E-06	0.937715928	normal	0.791269698	0.263670639	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[Z]	Cytoskeleton	Calponin homology (CH) domain;; Nuclear envelope localisation domain;; Spectrin repeat;; CAMSAP CH domain	Nesprin-2 GN=SYNE2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: nesprin-2 [Ceratotherium simum simum]
ENSG00000054690(PLEKHH1)	--	2.001008	287	2.212028	326	1.644247	242	2.184386	306	1.739172	258	1.829324	272	0.966117641	0.061330664	normal	0.844881853	-0.357060842	normal	0.955281228	0.159368301	normal	0.898714033	-0.054467953	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; 	--	--	[Z]	Cytoskeleton	PH domain;; MyTH4 domain;; Pleckstrin homology domain;; FERM central domain;; PH domain	Pleckstrin homology domain-containing family H member 1 GN=PLEKHH1 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: pleckstrin homology domain-containing family H member 1 [Ceratotherium simum simum]
ENSG00000054793(ATP9A)	--	16.30267476	2357	17.19657337	2513	16.01627299	2300	13.712324	1988	14.65029317	2072	16.42941986	2385	0.945514902	-0.276269879	normal	0.933691661	-0.299614308	normal	0.987817104	0.044035529	normal	0.356402082	-0.174554093	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|ptr:458341|ATP9A; ATPase, class II, type 9A; K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[P]	Inorganic ion transport and metabolism	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase IIA GN=ATP9A OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IIA [Erinaceus europaeus]
ENSG00000054938(CHRDL2)	--	0.228968592	7	0.662705119	18	1.483790477	13	0	0	0.038039764	0	0.28077152	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K17280|0|pps:100979924|CHRDL2; chordin-like 2; K17280 chordin-like protein 2 (A)	--	--	--	von Willebrand factor type C domain	Chordin-like protein 2 (Precursor) GN=CHRDL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: chordin-like protein 2 isoform X1 [Equus przewalskii]
ENSG00000054965(FAM168A)	--	18.1644	2189	18.53945	2162	17.35961	2129	16.202233	1810	15.49636	1828	12.285206	1604	0.922338906	-0.304878758	normal	0.950580529	-0.263326423	normal	0.702497241	-0.41645126	normal	0.039985393	-0.327422731	normal	--	--	--	--	--	--	--	Tongue Cancer Chemotherapy Resistant Protein 1	Protein FAM168A GN=FAM168A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM168A isoform X1 [Tupaia chinensis]
ENSG00000054967(RELT)	--	3.648942763	221	4.303566976	260	5.160335377	321	5.079511094	310	5.336249978	317	3.894422313	240	0.675014555	0.454709457	normal	0.921344759	0.263156552	normal	0.733716102	-0.425503577	normal	0.822776504	0.091085632	normal	--	--	--	"K05156|0|hsa:84957|RELT, TNFRSF19L, TRLT; RELT tumor necrosis factor receptor; K05156 tumor necrosis factor receptor superfamily member 19-like (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	Tumour necrosis factor receptor superfamily member 19	Tumor necrosis factor receptor superfamily member 19L (Precursor) GN=RELT OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 19L isoform X2 [Equus przewalskii] 
ENSG00000054983(GALC)	--	20.56214724	1189	18.31984766	1066	15.83861922	905	15.00720328	857	13.59041057	783	18.22339547	1050	0.321390864	-0.502445266	normal	0.497830979	-0.465775456	normal	0.956265939	0.205788664	normal	0.340487372	-0.253293499	normal	--	--	Molecular Function: galactosylceramidase activity (GO:0004336);; Biological Process: galactosylceramide catabolic process (GO:0006683);; 	K01202|0|hsa:2581|GALC; galactosylceramidase (EC:3.2.1.46); K01202 galactosylceramidase [EC:3.2.1.46] (A)	Sphingolipid metabolism (ko00600);; Lysosome (ko04142)	--	--	Glycosyl hydrolase family 59	Galactocerebrosidase (Precursor) GN=GALC OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: galactocerebrosidase isoform X1 [Tupaia chinensis]
ENSG00000055044(NOP58)	--	52.8151	2126	55.3904	2230	58.5755	2332	46.0779	1899	43.8822	1762	40.0062	1619	0.972873271	-0.19358582	normal	0.856394624	-0.360980233	normal	0.210895816	-0.53433799	normal	0.01975746	-0.362592989	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K14565|0|hsa:51602|NOP58, NOP5, NOP5/NOP58; NOP58 ribonucleoprotein; K14565 nucleolar protein 58 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	Putative snoRNA binding domain;; NOSIC (NUC001) domain;; NOP5NT (NUC127) domain	Nucleolar protein 58 GN=NOP58 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: nucleolar protein 58 isoform 2 [Odobenus rosmarus divergens]
ENSG00000055070(SZRD1)	--	37.44303628	2142	39.3562114	2232	38.29795601	2176	52.12771266	2998	47.26038698	2738	49.28526119	2843	0.586334248	0.45393329	normal	0.952071381	0.273191493	normal	0.834539114	0.377214094	normal	0.017412019	0.367914956	normal	--	--	--	--	--	--	--	SUZ domain;; SUZ-C motif	SUZ domain-containing protein 1 GN=SZRD1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: SUZ domain-containing protein 1 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000055118(KCNH2)	--	2.681267	177	1.335942	90	1.953249126	139	0.841959877	59	1.747098907	115	1.173544613	76	9.26E-08	-1.590650577	down	0.931778503	0.327334266	normal	0.078244006	-0.866365294	normal	0.216962557	-0.719621798	normal	[T]	Signal transduction mechanisms	"Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; "	"K04905|0|hsa:3757|KCNH2, ERG-1, ERG1, H-ERG, HERG, HERG1, Kv11.1, LQT2, SQT1; potassium voltage-gated channel, subfamily H (eag-related), member 2; K04905 potassium voltage-gated channel Eag-related subfamily H member 2 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; PAS domain;; Cyclic nucleotide-binding domain;; Ion channel;; PAS fold	Potassium voltage-gated channel subfamily H member 2 GN=KCNH2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	potassium voltage-gated channel subfamily H member 2 [Equus caballus] 
ENSG00000055130(CUL1)	--	27.96912372	1801	29.74694651	1912	27.6024044	1765	26.31008204	1714	24.81158708	1602	24.85890319	1608	0.982441451	-0.10217397	normal	0.939834358	-0.276395743	normal	0.97822708	-0.142564191	normal	0.358471075	-0.175320742	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	"K03347|0|ptr:463821|CUL1, cullin-1; cullin 1; K03347 cullin 1 (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Wnt signaling pathway (ko04310);; TGF-beta signaling pathway (ko04350);; Circadian rhythm (ko04710);; Herpes simplex infection (ko05168)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cullin family;; Cullin protein neddylation domain	Cullin-1 GN=CUL1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cullin-1 [Ornithorhynchus anatinus]
ENSG00000055147(FAM114A2)	--	7.805232	362	7.763055897	370	5.845232258	315	8.421983001	345	6.427022519	360	8.345986097	354	0.964123757	-0.09979167	normal	0.966499263	-0.060703377	normal	0.955509509	0.159383917	normal	0.996330974	-0.004917023	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF719)	Protein FAM114A2 GN=FAM114A2 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM114A2 [Equus caballus]
ENSG00000055163(CYFIP2)	--	27.56512816	2821	28.37623382	2913	30.8703173	3143	21.4518323	2276	20.2602404	2135	26.91778442	2773	0.896255529	-0.340331537	normal	0.539308	-0.469410285	normal	0.97976022	-0.188889269	normal	0.040421946	-0.325755908	normal	--	--	--	K05749|0|myd:102754916|CYFIP2; cytoplasmic FMR1 interacting protein 2; K05749 cytoplasmic FMR1 interacting protein (A)	RNA transport (ko03013);; Regulation of actin cytoskeleton (ko04810)	[R]	General function prediction only	Cytoplasmic Fragile-X interacting family	Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cytoplasmic FMR1-interacting protein 2 isoform X1 [Mustela putorius furo] 
ENSG00000055208(TAB2)	--	17.1495915	1323	17.03510551	1291	16.33866169	1244	18.66357561	1446	18.8891457	1443	18.59484629	1429	0.979905752	0.09731411	normal	0.975333061	0.139001673	normal	0.966070894	0.19151061	normal	0.496294523	0.141208897	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04404|0|ptr:463057|TAB2, MAP3K7IP2; TGF-beta activated kinase 1/MAP3K7 binding protein 2; K04404 TAK1-binding protein 2 (A)"	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Measles (ko05162);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	--	--	CUE domain;; Zn-finger in Ran binding protein and others	TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 GN=TAB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000055211(GINM1)	--	30.06571767	1010	26.99595075	904	26.68542378	884	29.92971505	1015	25.76951569	864	24.17270983	812	0.979487672	-0.023671908	normal	0.974562592	-0.086569864	normal	0.969998335	-0.130624844	normal	0.763770602	-0.078273495	normal	--	--	--	--	--	--	--	--	Glycoprotein integral membrane protein 1 (Precursor) GN=GINM1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: glycoprotein integral membrane protein 1 [Leptonychotes weddellii]
ENSG00000055332(EIF2AK2)	--	20.13380312	2894	21.26759082	3255	23.12708929	3413	18.41430871	2758	16.48925073	2344	16.20790753	2435	0.987504411	-0.100220216	normal	0.432132131	-0.494839286	normal	0.406687845	-0.49514906	normal	0.019146116	-0.364783209	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16195|0|hsa:5610|EIF2AK2, EIF2AK1, PKR, PPP1R83, PRKR; eukaryotic translation initiation factor 2-alpha kinase 2 (EC:2.7.11.1 2.7.10.2); K16195 eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[J]	"Translation, ribosomal structure and biogenesis"	Protein kinase domain;; Protein tyrosine kinase;; Double-stranded RNA binding motif;; Kinase-like	"Interferon-induced, double-stranded RNA-activated protein kinase GN=EIF2AK2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: interferon-induced, double-stranded RNA-activated protein kinase [Galeopterus variegatus]"
ENSG00000055483(USP36)	--	23.96355013	2032	27.15555765	2313	23.56812091	1973	23.03965233	1928	24.56235395	2169	30.85895735	2425	0.983501252	-0.106544893	normal	0.984046135	-0.114084725	normal	0.938083255	0.289102137	normal	0.935206041	0.025161057	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11855|0|hsa:57602|USP36, DUB1; ubiquitin specific peptidase 36 (EC:3.4.19.12); K11855 ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 36 GN=USP36 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 36 [Ceratotherium simum simum]
ENSG00000055609(KMT2C)	--	4.996331866	1371	5.033973796	1433	5.07883811	1314	6.69711865	1747	6.44891922	1855	5.676019726	1750	0.898442305	0.31850194	normal	0.862217461	0.350628	normal	0.726245185	0.404693288	normal	0.023359628	0.356860362	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	"K09188|0|hsa:58508|KMT2C, HALR, MLL3; lysine (K)-specific methyltransferase 2C (EC:2.1.1.43); K09188 histone-lysine N-methyltransferase MLL3 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[R]	General function prediction only	PHD-finger;; F/Y rich C-terminus;; SET domain;; PHD-like zinc-binding domain;; F/Y-rich N-terminus;; PHD-zinc-finger like domain;; HMG (high mobility group) box	Histone-lysine N-methyltransferase 2C GN=KMT2C OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: histone-lysine N-methyltransferase MLL3 [Ceratotherium simum simum]
ENSG00000055732(MCOLN3)	--	3.562864009	253	6.413940937	428	3.838510556	262	2.962027183	214	3.834483607	262	7.082182523	503	0.922711759	-0.270569687	normal	0.021103129	-0.726156519	normal	0.000139289	0.928763945	normal	0.983562217	0.034859377	normal	--	--	--	K04994|0|ggo:101142795|MCOLN3; mucolipin-3 isoform 1; K04994 mucolipin 3 (A)	--	[P]	Inorganic ion transport and metabolism	Polycystin cation channel	Mucolipin-3 GN=MCOLN3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: mucolipin-3 [Balaenoptera acutorostrata scammoni]
ENSG00000055813(CCDC85A)	--	0.745005946	51	0.7735805	47	0.313471063	22	1.180927122	88	1.421581262	107	1.073404678	81	0.598690599	0.739039223	normal	0.01209441	1.140492999	normal	5.11E-05	1.803245236	up	0.003502576	1.179152011	up	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved proteins (DUF2216)	Coiled-coil domain-containing protein 85A GN=CCDC85A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 85A [Myotis brandtii]
ENSG00000055917(PUM2)	--	38.31059273	3186	39.877267	3456	38.82410151	3410	30.033016	2789	28.91958531	2626	35.63025947	3225	0.973488558	-0.222715692	normal	0.760397436	-0.417452573	normal	0.989367244	-0.088723554	normal	0.168492753	-0.239136628	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; 	K17943|0|pon:100444313|PUM2; pumilio RNA-binding family member 2; K17943 pumilio RNA-binding family (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Pumilio-family RNA binding repeat	Pumilio homolog 2 GN=PUM2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: pumilio homolog 2 isoform X1 [Sorex araneus]
ENSG00000055950(MRPL43)	--	49.85532475	746	44.772935	676	51.9772328	781	48.22111415	741	49.83364	753	48.61052114	751	0.975417127	-0.04045076	normal	0.966557833	0.133916111	normal	0.974785343	-0.064673366	normal	0.989052177	0.006297481	normal	--	--	--	"K17424|7.0672e-109|hsa:84545|MRPL43, bMRP36a; mitochondrial ribosomal protein L43; K17424 large subunit ribosomal protein L43 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain	"39S ribosomal protein L43, mitochondrial (Precursor) GN=MRPL43 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: LOW QUALITY PROTEIN: 39S ribosomal protein L43, mitochondrial [Tursiops truncatus]"
ENSG00000055955(ITIH4)	--	0.403247024	28	0.507368862	33	0.220843337	12	0.14324735	9	0.14847152	8	0.186770933	13	0.505664109	-1.514888848	normal	0.062666095	-1.878500438	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Biological Process: hyaluronan metabolic process (GO:0030212);; 	--	--	--	--	Vault protein inter-alpha-trypsin domain;; Inter-alpha-trypsin inhibitor heavy chain C-terminus;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	35 kDa inter-alpha-trypsin inhibitor heavy chain H4 (Precursor) GN=ITIH4 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: inter-alpha-trypsin inhibitor heavy chain H4 isoform X1 [Panthera tigris altaica]
ENSG00000056050(HPF1)	--	15.40558992	317	18.2996584	358	18.3701016	351	14.40108056	287	14.53244095	295	13.79208355	282	0.952338886	-0.17338069	normal	0.896948548	-0.299276041	normal	0.878563039	-0.322513825	normal	0.319974437	-0.269101503	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2228)	UPF0609 protein C4orf27 GN=C4orf27 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0609 protein C4orf27 homolog [Ailuropoda melanoleuca]
ENSG00000056097(ZFR)	--	34.0609	3007	31.0533	2719	34.1165	2966	29.7028	2614	33.1325	2920	31.8751	2818	0.969748129	-0.232770293	normal	0.988012464	0.081421955	normal	0.988493201	-0.082095479	normal	0.737434437	-0.078406203	normal	--	--	--	"K13203|0|hsa:51663|ZFR, SPG71, ZFR1; zinc finger RNA binding protein; K13203 zinc finger RNA-binding protein (A)"	--	[R]	General function prediction only	DZF domain;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding	Zinc finger RNA-binding protein GN=ZFR OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger RNA-binding protein [Mustela putorius furo]
ENSG00000056277(ZNF280C)	--	5.0965111	317	3.950368416	248	4.965137133	263	4.0733861	236	4.202521993	246	4.327451469	260	0.666711799	-0.453967704	normal	0.965625587	-0.032906886	normal	0.96707708	-0.024699773	normal	0.585864755	-0.179177677	normal	--	--	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF4195)	Zinc finger protein 280C GN=ZNF280C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 280C [Ursus maritimus]
ENSG00000056291(NPFFR2)	--	0	0	0	0	0	0	0.048428917	1	0.047480183	0	0.124641705	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08375|0|ptr:471213|NPFFR2; neuropeptide FF receptor 2; K08375 neuropeptide FF receptor 2 (A)	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuropeptide FF receptor 2 GN=NPFFR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuropeptide FF receptor 2 [Odobenus rosmarus divergens]
ENSG00000056487(PHF21B)	--	0.540553991	37	0.21781599	16	0.91778071	32	1.098781746	32	0.781629978	26	0.254436534	19	0.980171801	-0.230004938	normal	0.968593844	0.631796104	normal	0.945474682	-0.716000483	normal	0.877704068	-0.164824648	normal	--	--	--	--	--	[R]	General function prediction only	PHD-finger	PHD finger protein 21B GN=PHF21B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: PHD finger protein 21B isoform X1 [Pteropus alecto]
ENSG00000056558(TRAF1)	--	1.35840076	185	1.11591197	155	1.530994238	188	1.077217593	134	0.843793892	111	1.03542249	131	0.71921857	-0.491307127	normal	0.757418647	-0.497372399	normal	0.647217407	-0.524376293	normal	0.118153116	-0.510929538	normal	--	--	--	"K03172|0|hsa:7185|TRAF1, EBI6, MGC:10353; TNF receptor-associated factor 1; K03172 TNF receptor-associated factor 1 (A)"	NF-kappa B signaling pathway (ko04064);; TNF signaling pathway (ko04668);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	MATH domain	TNF receptor-associated factor 1 GN=TRAF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TNF receptor-associated factor 1 isoform 1 [Ceratotherium simum simum]
ENSG00000056586(RC3H2)	--	12.61404029	1609	13.14090383	1792	12.836045	1648	11.9733624	1537	13.200181	1658	12.11059283	1705	0.981509017	-0.09678485	normal	0.979215965	-0.133436079	normal	0.984724961	0.04072731	normal	0.795087535	-0.064153622	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K15690|0|hsa:54542|RC3H2, MNAB, RNF164; ring finger and CCCH-type domains 2; K15690 RING finger and CCCH-type zinc finger domain-containing protein (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Roquin-2 GN=RC3H2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: RING finger and CCCH-type zinc finger domain-containing protein 2 [Equus caballus]
ENSG00000056736(IL17RB)	--	1.067580001	38	1.028476481	34	1.285057079	45	1.092131171	39	1.137817	39	1.346956	48	0.982345306	0.006387518	normal	0.979579257	0.169470827	normal	0.979074236	0.082144685	normal	0.936683745	0.08676652	normal	--	--	--	"K05165|0|hsa:55540|IL17RB, CRL4, EVI27, IL17BR, IL17RH1; interleukin 17 receptor B; K05165 interleukin 17 receptor B (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	SEFIR domain	Interleukin-17 receptor B (Precursor) GN=IL17RB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-17 receptor B [Ceratotherium simum simum]
ENSG00000056972(TRAF3IP2)	--	6.021206627	276	5.64134518	285	6.453112686	280	7.908813846	370	8.498065078	394	9.30474858	416	0.786557072	0.390143287	normal	0.664048767	0.443796452	normal	0.267326114	0.560366606	normal	0.037614586	0.467773217	normal	--	--	--	--	--	--	--	SEFIR domain	Adapter protein CIKS GN=TRAF3IP2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: adapter protein CIKS isoform 1 [Ceratotherium simum simum] 
ENSG00000056998(GYG2)	--	10.7413078	657	11.02384035	538	9.308469258	571	7.434671205	457	9.886285591	593	9.129476116	544	0.198449961	-0.552971488	normal	0.96560562	0.118681533	normal	0.970218504	-0.077963962	normal	0.490810223	-0.168469582	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K00750|0|hsa:8908|GYG2, GN-2, GN2; glycogenin 2 (EC:2.4.1.186); K00750 glycogenin glucosyltransferase [EC:2.4.1.186] (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyl transferase family 8	Glycogenin-2 GN=GYG2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: glycogenin-2 [Galeopterus variegatus]
ENSG00000057019(DCBLD2)	--	331.4820889	32280	294.3834863	28707	342.3752049	33034	409.56343	40475	349.17108	34066	285.447237	28090	0.991879157	0.295545654	normal	0.995674661	0.225492513	normal	0.994829904	-0.242174453	normal	0.730215334	0.104286321	normal	--	--	--	--	--	--	--	F5/8 type C domain;; CUB domain;; LCCL domain	"Discoidin, CUB and LCCL domain-containing protein 2 (Precursor) GN=DCBLD2 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	hypothetical protein PANDA_015073 [Ailuropoda melanoleuca]
ENSG00000057149(SERPINB3)	--	0	0	0	0	0	0	0.190931362	6	0.465366658	14	0.316978115	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13963|0|hsa:6317|SERPINB3, HsT1196, SCC, SCCA-1, SCCA-PD, SCCA1, T4-A; serpin peptidase inhibitor, clade B (ovalbumin), member 3; K13963 serpin B (A)"	Amoebiasis (ko05146)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B3 GN=SERPINB3 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: serpin B3-like [Equus caballus]
ENSG00000057252(SOAT1)	--	20.435714	1494	23.61842013	1499	20.62964771	1523	20.0992907	1525	20.04781469	1460	28.06683749	2001	0.984110224	-0.001201946	normal	0.982406671	-0.05939785	normal	0.79029903	0.385179118	normal	0.677187072	0.122467795	normal	--	--	--	K00637|0|ptr:457553|SOAT1; sterol O-acyltransferase 1; K00637 sterol O-acyltransferase [EC:2.3.1.26] (A)	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	"MBOAT, membrane-bound O-acyltransferase family"	Sterol O-acyltransferase 1 GN=SOAT1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: sterol O-acyltransferase 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000057294(PKP2)	--	4.496233941	368	4.030850691	304	4.882992957	396	8.662594	699	6.384259537	518	6.585377138	537	0.000124774	0.892009032	normal	0.010285262	0.74458512	normal	0.655578068	0.429715779	normal	0.002244038	0.693959869	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12642|0|hsa:5318|PKP2, ARVD9; plakophilin 2; K12642 plakophilin 2 (A)"	Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat	Plakophilin-2 GN=PKP2 OS=Homo sapiens (Human) PE=1 SV=2	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: plakophilin-2 [Ceratotherium simum simum]
ENSG00000057468(MSH4)	--	0	0	0	0	0	0	0.0365545	2	0.0710313	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	K08740|0|hsa:4438|MSH4; mutS homolog 4; K08740 DNA mismatch repair protein MSH4 (A)	--	[L]	"Replication, recombination and repair"	MutS domain V;; MutS domain III;; MutS domain II;; MutS family domain IV	MutS protein homolog 4 GN=MSH4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: mutS protein homolog 4 [Galeopterus variegatus]
ENSG00000057593(F7)	--	0.050018386	3	0.014393342	1	0.016015422	0	0.016709181	1	0	0	0.016465367	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	"K01320|0|hsa:2155|F7, SPCA; coagulation factor VII (serum prothrombin conversion accelerator) (EC:3.4.21.21); K01320 coagulation factor VII [EC:3.4.21.21] (A)"	Complement and coagulation cascades (ko04610)	--	--	Trypsin;; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain;; Domain of unknown function (DUF1986);; EGF-like domain	Factor VII heavy chain (Precursor) GN=F7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: coagulation factor VII [Galeopterus variegatus]
ENSG00000057608(GDI2)	--	126.703404	5031	128.3347403	5084	126.2916687	4939	149.9406043	5984	141.9615033	5601	125.4961531	5010	0.98349333	0.219371236	normal	0.991441758	0.118260317	normal	0.993362418	0.012296454	normal	0.588971159	0.118843958	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: GDP-dissociation inhibitor activity (GO:0005092);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17255|0|nle:100579667|GDI2; GDP dissociation inhibitor 2; K17255 Rab GDP dissociation inhibitor (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	GDP dissociation inhibitor	Rab GDP dissociation inhibitor beta GN=GDI2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: rab GDP dissociation inhibitor beta-like [Tupaia chinensis]
ENSG00000057657(PRDM1)	--	0.54394892	42	0.956591482	40	0.558929401	44	0.352926905	35	0.977113315	91	0.868822058	79	0.975867365	-0.28252711	normal	0.031596583	1.135245401	normal	0.522028806	0.814877051	normal	0.329083233	0.683366836	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; SET domain"	PR domain zinc finger protein 1 GN=PRDM1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: PR domain zinc finger protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000057663(ATG5)	--	11.16784321	547	13.0204854	632	12.94504107	596	12.54479	616	12.4827162	609	12.357986	571	0.963404577	0.140186067	normal	0.970959885	-0.074726717	normal	0.971279872	-0.069931723	normal	0.995540642	-0.004443541	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: autophagy (GO:0006914);; 	"K08339|0|ptr:462905|ATG5, APG5L; autophagy related 5; K08339 autophagy-related protein 5 (A)"	Regulation of autophagy (ko04140);; RIG-I-like receptor signaling pathway (ko04622)	[O]	"Posttranslational modification, protein turnover, chaperones"	Autophagy protein Apg5	Autophagy protein 5 GN=ATG5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: autophagy protein 5 [Trichechus manatus latirostris]
ENSG00000057704(TMCC3)	--	0.512951799	46	0.472424595	14	0.212345858	19	0.6158991	38	0.631722851	47	0.423558212	32	0.973071365	-0.295585602	normal	0.030673154	1.624890754	normal	0.94872274	0.700403054	normal	0.515548539	0.544590002	normal	--	--	--	--	--	[S]	Function unknown	Predicted transmembrane and coiled-coil 2 protein	Transmembrane and coiled-coil domains protein 3 GN=TMCC3 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane and coiled-coil domains protein 3 [Loxodonta africana]
ENSG00000057757(PITHD1)	--	15.80478858	405	13.11226314	348	14.41054182	380	15.73668539	408	16.01823105	413	14.57510659	371	0.969648315	-0.020109015	normal	0.936916049	0.224730572	normal	0.96849218	-0.042699687	normal	0.890265455	0.05184495	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	PITH domain	PITH domain-containing protein 1 GN=PITHD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: PITH domain-containing protein 1 [Oryctolagus cuniculus]
ENSG00000057935(MTA3)	--	28.11265933	1104	28.54034566	1173	26.80969668	1071	15.655159	718	20.56213774	888	14.28203512	682	0.022606391	-0.650384815	normal	0.662673921	-0.422369916	normal	0.019846464	-0.658231421	normal	0.00019066	-0.570539804	normal	--	--	"Molecular Function: chromatin binding (GO:0003682);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K11660|0|ptr:459183|MTA3; metastasis associated 1 family, member 3; K11660 metastasis-associated protein MTA (A)"	--	[B]	Chromatin structure and dynamics	BAH domain;; ELM2 domain;; GATA zinc finger	Metastasis-associated protein MTA3 GN=MTA3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: metastasis-associated protein MTA3 [Ceratotherium simum simum]
ENSG00000058056(USP13)	--	4.515268794	580	5.199194698	659	5.13873737	628	3.958104262	490	4.565408553	581	4.500921049	548	0.91306679	-0.273314551	normal	0.949223098	-0.202671134	normal	0.948464271	-0.20435287	normal	0.304367836	-0.226420195	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11836|0|hsa:8975|USP13, ISOT3, IsoT-3; ubiquitin specific peptidase 13 (isopeptidase T-3) (EC:3.4.19.12); K11836 ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; UBA/TS-N domain;; Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein	Ubiquitin carboxyl-terminal hydrolase 13 GN=USP13 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 13 isoform 1 [Dasypus novemcinctus]
ENSG00000058063(ATP11B)	--	8.008048567	817	8.293275623	859	7.851023809	793	8.25137088	819	6.523277899	690	7.30684541	758	0.976909784	-0.027253701	normal	0.854278504	-0.336825207	normal	0.974419326	-0.073271523	normal	0.529341538	-0.144747134	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:23200|ATP11B, ATPIF, ATPIR; ATPase, class VI, type 11B (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase IF GN=ATP11B OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IF [Leptonychotes weddellii]
ENSG00000058085(LAMC2)	--	6.10490729	717	3.410563974	406	5.929275	705	61.69687997	7196	44.14346042	5129	15.9480982	1857	0	3.293573879	up	0	3.63280377	up	4.65E-14	1.387082473	up	0.009183271	2.931675707	up	--	--	--	"K06246|0|hsa:3918|LAMC2, B2T, BM600, CSF, EBR2, EBR2A, LAMB2T, LAMNB2; laminin, gamma 2; K06246 laminin, gamma 2 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin B (Domain IV)	Laminin subunit gamma-2 (Precursor) GN=LAMC2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: laminin subunit gamma-2 [Galeopterus variegatus]
ENSG00000058091(CDK14)	--	2.726983345	210	1.829886018	121	1.827437008	155	0.47596957	41	0.559215486	48	0.58635412	46	3.33E-16	-2.344297493	down	0.000410273	-1.328035027	down	4.34E-08	-1.728022763	down	1.89E-05	-1.86879294	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08821|0|hsa:5218|CDK14, PFTAIRE1, PFTK1; cyclin-dependent kinase 14 (EC:2.7.11.22); K08821 cyclin-dependent kinase 14 [EC:2.7.11.22] (A)"	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 14 GN=CDK14 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 14 [Felis catus] 
ENSG00000058262(SEC61A1)	--	64.91773921	3973	71.07247237	4423	72.87820167	4492	97.97637233	5979	94.03600856	5716	113.0184697	6835	0.187508456	0.558665943	normal	0.926860066	0.348449062	normal	0.090170599	0.597127831	normal	0.00087652	0.503118133	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: protein transport (GO:0015031);; Cellular Component: membrane (GO:0016020);; 	K10956|0|mcf:102116756|SEC61A1; Sec61 alpha 1 subunit (S. cerevisiae); K10956 protein transport protein SEC61 subunit alpha (A)	Protein export (ko03060);; Protein processing in endoplasmic reticulum (ko04141);; Phagosome (ko04145)	[UO]	"Intracellular trafficking, secretion, and vesicular transport;; Posttranslational modification, protein turnover, chaperones"	SecY translocase;; Plug domain of Sec61p	Protein transport protein Sec61 subunit alpha isoform 1 GN=SEC61A1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec61 subunit alpha isoform 1 [Mustela putorius furo] 
ENSG00000058272(PPP1R12A)	--	13.57361949	1371	13.60370208	1505	15.78645114	1702	15.8494525	1776	17.23155132	1854	15.55489101	1630	0.86774306	0.342232992	normal	0.936669873	0.279198042	normal	0.983649983	-0.07058642	normal	0.346809697	0.179240385	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: protein kinase binding (GO:0019901);; 	"K06270|0|hsa:4659|PPP1R12A, M130, MBS, MYPT1; protein phosphatase 1, regulatory subunit 12A; K06270 protein phosphatase 1 regulatory subunit 12A (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Proteoglycans in cancer (ko05205)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Protein phosphatase 1 regulatory subunit 12A GN=PPP1R12A OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: protein phosphatase 1 regulatory subunit 12A isoform X1 [Physeter catodon] 
ENSG00000058335(RASGRF1)	--	0	0	0.0905843	5	0.012623252	0	0.341300649	21	0.251903058	19	0.362740425	23	0.002751624	3.860278256	up	--	--	--	0.000616501	4.014815783	up	--	--	--	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K04349|0|pps:100994899|RASGRF1; Ras protein-specific guanine nucleotide-releasing factor 1; K04349 Ras-specific guanine nucleotide-releasing factor 1 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Focal adhesion (ko04510)	[T]	Signal transduction mechanisms	RasGEF domain;; RhoGEF domain;; PH domain;; RasGEF N-terminal motif	Ras-specific guanine nucleotide-releasing factor 1 GN=RASGRF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ras-specific guanine nucleotide-releasing factor 1 isoform X1 [Loxodonta africana]
ENSG00000058404(CAMK2B)	--	0.012307824	1	0.020129994	1	0.023639468	1	0.18024458	3	0.068211703	5	0.04866599	4	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: calmodulin-dependent protein kinase activity (GO:0004683);; Molecular Function: calmodulin binding (GO:0005516);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04515|0|hsa:816|CAMK2B, CAM2, CAMK2, CAMKB; calcium/calmodulin-dependent protein kinase II beta (EC:2.7.11.17); K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] (A)"	ErbB signaling pathway (ko04012);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; HIF-1 signaling pathway (ko04066);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Wnt signaling pathway (ko04310);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; Proteoglycans in cancer (ko05205);; Glioma (ko05214)	[T]	Signal transduction mechanisms	Protein kinase domain;; Calcium/calmodulin dependent protein kinase II Association;; Protein tyrosine kinase;; Domain of unknown function (DUF4440);; SnoaL-like domain	Calcium/calmodulin-dependent protein kinase type II subunit beta GN=CAMK2B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [Bos taurus]
ENSG00000058453(CROCC)	--	1.931638314	265	1.946954887	289	1.638275708	239	2.017585396	291	2.486077969	346	2.506200482	350	0.962702478	0.103621108	normal	0.932212094	0.237140634	normal	0.38343793	0.539216979	normal	0.270092416	0.294854757	normal	--	--	--	"K16469|0|hsa:9696|CROCC, ROLT; ciliary rootlet coiled-coil, rootletin; K16469 rootletin (A)"	--	--	--	"Ciliary rootlet component, centrosome cohesion"	Rootletin OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: rootletin [Vicugna pacos]
ENSG00000058600(POLR3E)	--	13.72631727	749	11.07050266	663	12.66566927	744	15.54972657	829	15.71005013	850	13.57727186	761	0.970798595	0.115349155	normal	0.854626904	0.33634832	normal	0.976082097	0.024253645	normal	0.487245905	0.157237326	normal	--	--	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K14721|0|hsa:101060521|DNA-directed RNA polymerase III subunit RPC5-like; K14721 DNA-directed RNA polymerase III subunit RPC5 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	Sin-like protein conserved region	DNA-directed RNA polymerase III subunit RPC5 GN=POLR3E OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC5 isoform X1 [Equus caballus]
ENSG00000058668(ATP2B4)	--	10.95808083	1856	8.315764	1443	9.807639028	1664	10.41625406	1759	9.770850932	1661	8.656106255	1452	0.982338593	-0.108181481	normal	0.970676733	0.18137693	normal	0.965649076	-0.204706094	normal	0.864496211	-0.048375521	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: calcium-transporting ATPase activity (GO:0005388);; 	"K05850|0|pps:100988724|ATP2B4; ATPase, Ca++ transporting, plasma membrane 4; K05850 Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Salivary secretion (ko04970);; Pancreatic secretion (ko04972)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; Plasma membrane calcium transporter ATPase C terminal;; haloacid dehalogenase-like hydrolase;; Cation transporter/ATPase, N-terminus;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Plasma membrane calcium-transporting ATPase 4 GN=ATP2B4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: plasma membrane calcium-transporting ATPase 4 isoform 2 [Ceratotherium simum simum]
ENSG00000058673(ZC3H11A)	--	26.52313243	3923	27.36606876	4083	27.15192975	3800	25.22838107	3961	28.3261845	4300	29.93203932	4566	0.9920369	-0.016918304	normal	0.99174248	0.053261311	normal	0.970950058	0.256546735	normal	0.665792573	0.098814664	normal	--	--	--	--	--	[S]	Function unknown	--	Zinc finger CCCH domain-containing protein 11A GN=ZC3H11A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger CCCH domain-containing protein 11A isoform 1 [Odobenus rosmarus divergens] 
ENSG00000058729(RIOK2)	--	7.039697548	399	8.827767502	518	7.8249306	410	7.969468604	489	7.126311397	404	7.568042845	470	0.919876777	0.261701941	normal	0.786711513	-0.378767659	normal	0.950411021	0.188096948	normal	0.969826596	0.016969454	normal	[T]	Signal transduction mechanisms	"Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K07179|0|ptr:461961|RIOK2; RIO kinase 2; K07179 RIO kinase 2 [EC:2.7.11.1] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[TR]	Signal transduction mechanisms;; General function prediction only	"RIO1 family;; Rio2, N-terminal;; Phosphotransferase enzyme family;; Lipopolysaccharide kinase (Kdo/WaaP) family"	Serine/threonine-protein kinase RIO2 GN=RIOK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase RIO2 [Myotis lucifugus]
ENSG00000058799(YIPF1)	--	10.9746439	305	9.602841905	275	11.99278305	332	12.87662784	368	12.92627246	358	12.09319739	344	0.931928882	0.238967118	normal	0.84008599	0.357374584	normal	0.967762084	0.042742605	normal	0.466177253	0.209385656	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Yip1 domain	Protein YIPF1 GN=YIPF1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein YIPF1 isoform X1 [Camelus ferus] 
ENSG00000058804(NDC1)	--	25.0773944	1686	25.0959567	1684	23.393976	1544	26.3174148	1792	24.2358317	1622	23.056582	1552	0.984598305	0.057083378	normal	0.982952228	-0.075475808	normal	0.984402895	-0.000834822	normal	0.986272296	-0.006610066	normal	--	--	--	"K14315|0|pps:100982074|NDC1, TMEM48; NDC1 transmembrane nucleoporin; K14315 nucleoporin NDC1 (A)"	RNA transport (ko03013)	[S]	Function unknown	Nucleoporin protein Ndc1-Nup	Nucleoporin NDC1 GN=NDC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nucleoporin NDC1 isoform X1 [Vicugna pacos]
ENSG00000058866(DGKG)	--	2.221923803	361	2.698899876	445	2.301111235	386	2.070740479	339	1.914608307	310	2.057768081	372	0.961659534	-0.121014194	normal	0.32210906	-0.540749068	normal	0.967680963	-0.06134483	normal	0.346202276	-0.244477156	normal	--	--	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|pps:100990657|DGKG; diacylglycerol kinase, gamma 90kDa; K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase N-terminus;; Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; EF-hand domain pair;; EF hand	Diacylglycerol kinase gamma GN=DGKG OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: diacylglycerol kinase gamma isoform X1 [Mustela putorius furo] 
ENSG00000059122(FLYWCH1)	--	15.79201468	1042	13.27533728	932	17.77883641	1066	18.01965736	1170	16.27565326	1046	18.43946061	1131	0.972942683	0.136131495	normal	0.969685851	0.144832513	normal	0.978482534	0.076993994	normal	0.60106109	0.117621534	normal	--	--	--	--	--	--	--	FLYWCH zinc finger domain;; FLYWCH-type zinc finger-containing protein	FLYWCH-type zinc finger-containing protein 1 GN=FLYWCH1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: FLYWCH-type zinc finger-containing protein 1 [Vicugna pacos]
ENSG00000059145(UNKL)	--	19.59258438	1097	22.24629478	1367	21.53297667	1328	16.22358999	1002	19.61376635	1176	19.23049116	1215	0.968210113	-0.161276818	normal	0.950032819	-0.238267234	normal	0.975017913	-0.136427791	normal	0.373226704	-0.180885993	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	"Zinc finger, C3HC4 type (RING finger);; Zinc finger C-x8-C-x5-C-x3-H type (and similar)"	Putative E3 ubiquitin-protein ligase UNKL GN=UNKL OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: putative E3 ubiquitin-protein ligase UNKL isoform X1 [Eptesicus fuscus]
ENSG00000059377(TBXAS1)	--	4.122805	52	2.9316874	41	3.261221001	37	5.2089224	104	3.3214647	78	3.46843	74	0.107776169	0.948982221	normal	0.400161494	0.882456227	normal	0.29534222	0.963346968	normal	0.024893522	0.954969784	normal	--	--	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K01832|0|hsa:6916|TBXAS1, BDPLT14, CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS; thromboxane A synthase 1 (platelet) (EC:5.3.99.5); K01832 thromboxane-A synthase [EC:5.3.99.5] (A)"	Arachidonic acid metabolism (ko00590);; Platelet activation (ko04611)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Thromboxane-A synthase GN=TBXAS1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: thromboxane-A synthase [Ceratotherium simum simum]
ENSG00000059378(PARP12)	--	4.709082513	286	4.61180191	271	4.578503707	279	6.474898824	388	7.203939357	428	6.366243523	388	0.748268421	0.407324356	normal	0.102870449	0.635048732	normal	0.597365463	0.465351875	normal	0.021718864	0.505140088	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; Molecular Function: metal ion binding (GO:0046872);; 	"K15259|0|hsa:64761|PARP12, ARTD12, MST109, MSTP109, ZC3H1, ZC3HDC1; poly (ADP-ribose) polymerase family, member 12 (EC:2.4.2.30); K15259 poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain;; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; WWE domain	Poly [ADP-ribose] polymerase 12 GN=PARP12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: poly [ADP-ribose] polymerase 12 [Canis lupus familiaris]
ENSG00000059573(ALDH18A1)	--	30.22822	2020	29.25002	1973	29.18155	1952	39.00035	2604	40.37005	2675	29.43382	1961	0.897375358	0.335316759	normal	0.73405085	0.41744563	normal	0.986685737	-0.001653681	normal	0.206847996	0.262359764	normal	[E]	Amino acid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K12657|0|pps:100969924|ALDH18A1; aldehyde dehydrogenase 18 family, member A1; K12657 delta-1-pyrroline-5-carboxylate synthetase [EC:2.7.2.11 1.2.1.41] (A)"	Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Amino acid kinase family;; Aldehyde dehydrogenase family	Gamma-glutamyl phosphate reductase GN=ALDH18A1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: delta-1-pyrroline-5-carboxylate synthase isoform X1 [Ursus maritimus]
ENSG00000059588(TARBP1)	--	16.9211832	1808	16.31593718	1622	15.66151839	1559	16.4897351	1695	15.78608053	1585	18.52418578	1815	0.980659721	-0.123832953	normal	0.983464561	-0.054665975	normal	0.965544335	0.210867434	normal	0.980304766	0.009168581	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; Molecular Function: RNA methyltransferase activity (GO:0008173);; 	--	--	[A]	RNA processing and modification	SpoU rRNA Methylase family	Probable methyltransferase TARBP1 GN=TARBP1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable methyltransferase TARBP1 isoform X1 [Oryctolagus cuniculus]
ENSG00000059691(GATB)	--	5.576535	223	5.89369	282	5.5366048	265	6.919621002	277	6.830861073	262	6.925993141	314	0.916194003	0.280274695	normal	0.959005127	-0.126848957	normal	0.934615337	0.235246094	normal	0.723148269	0.126880571	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: ligase activity (GO:0016874);; Molecular Function: carbon-nitrogen ligase activity, with glutamine as amido-N-donor (GO:0016884);; "	"K02434|0|hsa:5188|GATB, PET112, PET112L; glutamyl-tRNA(Gln) amidotransferase, subunit B; K02434 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit B [EC:6.3.5.6 6.3.5.7] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	GatB/GatE catalytic domain;; GatB domain	"Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03147} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial [Pteropus alecto] "
ENSG00000059728(MXD1)	--	21.11073355	790	18.32471686	700	21.31674161	786	14.567726	650	16.03028676	657	14.49213703	652	0.882066496	-0.31157587	normal	0.968637313	-0.112636873	normal	0.914156522	-0.277361959	normal	0.241963185	-0.237432179	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09114|6.81475e-115|pps:100967991|MXD1; MAX dimerization protein 1; K09114 MAX dimerization protein (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Max dimerization protein 1 GN=MXD1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: max dimerization protein 1 isoform X1 [Condylura cristata]
ENSG00000059758(CDK17)	--	9.829750326	649	10.50615714	644	10.383958	680	9.471828311	631	11.55047442	742	10.34861313	686	0.972142666	-0.071239683	normal	0.956612548	0.182532357	normal	0.975201703	0.004372706	normal	0.899494571	0.040766438	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K15595|0|mcf:102118715|CDK17; cyclin-dependent kinase 17; K15595 cyclin-dependent kinase 17 [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Cyclin-dependent kinase 17 GN=CDK17 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cyclin-dependent kinase 17 [Sus scrofa] 
ENSG00000059769(DNAJC25)	--	99.43252	2001	111.36035	2281	102.47888	2058	96.1494	1956	88.79807	1794	93.21616	1893	0.985689788	-0.063597667	normal	0.845906457	-0.367637537	normal	0.981718036	-0.128761325	normal	0.307944479	-0.189440025	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 25 GN=DNAJC25 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 25 [Ailuropoda melanoleuca] 
ENSG00000059804(SLC2A3)	--	24.61485416	1378	33.14512717	1951	31.64633254	1779	29.359414	1727	24.409338	1416	44.56487033	2551	0.921415001	0.294566053	normal	0.439238449	-0.483377217	normal	0.305995354	0.511340049	normal	0.831204751	0.136685609	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08142|0|hsa:6515|SLC2A3, GLUT3; solute carrier family 2 (facilitated glucose transporter), member 3; K08142 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 3 (A)"	--	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily;; Reduced folate carrier	"Solute carrier family 2, facilitated glucose transporter member 3 GN=SLC2A3 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 3 isoform X2 [Galeopterus variegatus]"
ENSG00000059915(PSD)	--	0.2472279	11	0.138623	11	0.3025291	11	0.1749219	8	0.0747532	5	0.0870714	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K12494|0|hsa:5662|PSD, EFA6, EFA6A, PSD1, TYL; pleckstrin and Sec7 domain containing; K12494 PH and SEC7 domain-containing protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; Pleckstrin homology domain;; PH domain	PH and SEC7 domain-containing protein 1 GN=PSD OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PH and SEC7 domain-containing protein 1 [Camelus ferus]
ENSG00000060069(CTDP1)	--	8.90313288	724	7.6849395	646	7.659286643	667	9.324099556	793	10.80578923	866	10.3320716	858	0.971873531	0.100295498	normal	0.725269372	0.400593759	normal	0.822334176	0.354289417	normal	0.134357373	0.284312059	normal	[K]	Transcription	--	"K15732|0|pps:100968379|CTDP1; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1; K15732 RNA polymerase II subunit A C-terminal domain phosphatase [EC:3.1.3.16] (A)"	--	[K]	Transcription	"FCP1, C-terminal;; NLI interacting factor-like phosphatase;; twin BRCT domain"	RNA polymerase II subunit A C-terminal domain phosphatase GN=CTDP1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: RNA polymerase II subunit A C-terminal domain phosphatase isoformX1 [Canis lupus familiaris]
ENSG00000060138(YBX3)	--	115.0156	3830	116.62705	3870	116.4772	3905	138.99954	4585	125.21376	4189	145.793	4895	0.978017479	0.228661155	normal	0.990448895	0.092810895	normal	0.94373071	0.317584796	normal	0.238557037	0.21514758	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K06099|6.77827e-133|pps:100974418|YBX3, CSDA; Y box binding protein 3; K06099 cold shock domain protein A (A)"	Tight junction (ko04530)	[J]	"Translation, ribosomal structure and biogenesis"	'Cold-shock' DNA-binding domain	Y-box-binding protein 3 GN=YBX3 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: Y-box-binding protein 3, partial [Galeopterus variegatus]"
ENSG00000060140(STYK1)	--	0.552573905	30	0.600329186	33	0.292880711	15	0.209055544	12	0.355311399	19	0.03842414	2	0.714106115	-1.248501321	normal	0.926713312	-0.770789065	normal	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17510|0|hsa:55359|STYK1, NOK, SuRTK106; serine/threonine/tyrosine kinase 1 (EC:2.7.10.2); K17510 tyrosine-protein kinase STYK1 [EC:2.7.10.2] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Tyrosine-protein kinase STYK1 GN=STYK1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase STYK1 [Galeopterus variegatus]
ENSG00000060237(WNK1)	--	38.93479205	6854	45.67309205	7978	42.41486521	7536	41.49817763	7020	45.1719841	7925	44.94994508	7798	0.994961185	0.003691757	normal	0.995213421	-0.031036843	normal	0.995158404	0.041005658	normal	0.996314771	0.003146306	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08867|0|ggo:101149918|WNK1; serine/threonine-protein kinase WNK1; K08867 WNK lysine deficient protein kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Oxidative-stress-responsive kinase 1 C terminal	Serine/threonine-protein kinase WNK1 GN=WNK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase WNK1 isoform 1 [Ceratotherium simum simum]
ENSG00000060339(CCAR1)	--	27.93593546	2341	37.08308745	3068	30.81298256	2552	35.21366221	2927	35.31781404	3039	38.2564899	3236	0.942763961	0.291294286	normal	0.989833878	-0.035110976	normal	0.910515587	0.334115617	normal	0.313585257	0.187953772	normal	--	--	--	--	--	[R]	General function prediction only	DBC1;; S1-like;; SAP domain	Cell division cycle and apoptosis regulator protein 1 GN=CCAR1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cell division cycle and apoptosis regulator protein 1 isoform X3 [Ursus maritimus]
ENSG00000060491(OGFR)	--	18.92187905	1004	17.17943109	950	18.885894	1085	22.99460148	1168	21.79568502	1158	19.622506	1100	0.963226818	0.187182984	normal	0.932475806	0.263828357	normal	0.980580667	0.011501118	normal	0.471294888	0.151774417	normal	--	--	Molecular Function: receptor activity (GO:0004872);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Opioid growth factor receptor (OGFr) conserved region;; Opioid growth factor receptor repeat	Opioid growth factor receptor GN=OGFR OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: opioid growth factor receptor [Galeopterus variegatus]
ENSG00000060558(GNA15)	--	0.0245144	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04637|0|pps:100987012|GNA15; guanine nucleotide binding protein (G protein), alpha 15 (Gq class); K04637 guanine nucleotide-binding protein subunit alpha-15 (A)"	Calcium signaling pathway (ko04020);; Chagas disease (American trypanosomiasis) (ko05142);; Amoebiasis (ko05146)	[T]	Signal transduction mechanisms	G-protein alpha subunit;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Guanine nucleotide-binding protein subunit alpha-15 GN=GNA15 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit alpha-15 [Odobenus rosmarus divergens]
ENSG00000060566(CREB3L3)	--	0.026832991	2	0.039725852	1	0	0	0.210451434	11	0.185172663	14	0.176151449	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09048|0|hsa:84699|CREB3L3, CREB-H, CREBH; cAMP responsive element binding protein 3-like 3; K09048 cyclic AMP-responsive element-binding protein 3 (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Processed cyclic AMP-responsive element-binding protein 3-like protein 3 GN=CREB3L3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cyclic AMP-responsive element-binding protein 3-like protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000060642(PIGV)	--	13.281437	423	10.6380487	343	12.307829	378	9.102637	267	8.002745	237	11.995653	325	0.035735309	-0.691458711	normal	0.355701132	-0.551803448	normal	0.937524076	-0.225265032	normal	0.030956037	-0.485272081	normal	[S]	Function unknown	Molecular Function: dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity (GO:0004584);; Biological Process: GPI anchor biosynthetic process (GO:0006506);; 	"K07542|0|hsa:55650|PIGV, GPI-MT-II, HPMRS1, PIG-V; phosphatidylinositol glycan anchor biosynthesis, class V (EC:2.3.1.225); K07542 phosphatidylinositol glycan, class V [EC:2.4.1.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[R]	General function prediction only	Mannosyltransferase (PIG-V))	GPI mannosyltransferase 2 GN=PIGV OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GPI mannosyltransferase 2 [Galeopterus variegatus]
ENSG00000060656(PTPRU)	--	5.981081875	669	5.390609595	611	4.855904938	555	7.966779113	887	9.592262921	1067	9.944873523	1118	0.779127524	0.375344903	normal	0.001275626	0.78140786	normal	1.31E-06	1.000110338	up	9.36E-06	0.722705265	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; Cellular Component: membrane (GO:0016020);; 	"K16662|0|ptr:456692|PTPRU; protein tyrosine phosphatase, receptor type, U; K16662 receptor-type tyrosine-protein phosphatase U [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; MAM domain;; Fibronectin type III domain;; Dual specificity phosphatase, catalytic domain;; Tyrosine phosphatase family"	Receptor-type tyrosine-protein phosphatase U (Precursor) GN=PTPRU OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase U isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000060688(SNRNP40)	--	28.982003	634	33.33588	676	30.88077	670	33.37909	724	35.128497	722	27.604581	586	0.961741015	0.160310867	normal	0.972494038	0.073390154	normal	0.950408776	-0.201066208	normal	0.967635723	0.015669303	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K12857|0|pps:100968772|SNRNP40; small nuclear ribonucleoprotein 40kDa (U5); K12857 Prp8 binding protein (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	U5 small nuclear ribonucleoprotein 40 kDa protein GN=SNRNP40 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U5 small nuclear ribonucleoprotein 40 kDa protein [Oryctolagus cuniculus]
ENSG00000060718(COL11A1)	--	0.01291458	1	0.006207374	1	0.014443899	1	1.715177193	267	2.642231813	374	2.235575638	365	0	6.704770862	up	0	7.208793074	up	0	7.182938919	up	1.82E-51	8.369246238	up	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; 	"K06236|0|ptr:457065|COL11A1; collagen, type XI, alpha 1; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; Laminin G domain;; Concanavalin A-like lectin/glucanases superfamily	Collagen alpha-1(XI) chain (Precursor) GN=COL11A1 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: collagen alpha-1(XI) chain isoform X2 [Camelus dromedarius]
ENSG00000060749(QSER1)	--	16.80827538	2573	20.13391252	3007	17.94834473	2674	16.96574248	2628	16.77807084	2529	16.41076103	2513	0.98913893	-0.000318257	normal	0.956157072	-0.271035539	normal	0.986817164	-0.097823157	normal	0.542846755	-0.127305511	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF4211)	Glutamine and serine-rich protein 1 GN=QSER1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: glutamine and serine-rich protein 1 [Orcinus orca]
ENSG00000060762(MPC1)	--	2.894012614	36	3.521693575	45	2.367344686	30	6.167625337	78	5.993411056	77	6.311905674	81	0.139897139	1.053419995	normal	0.679436293	0.734434678	normal	0.004978473	1.380677969	up	0.014721551	1.06658451	normal	--	--	Cellular Component: mitochondrial inner membrane (GO:0005743);; Biological Process: mitochondrial pyruvate transport (GO:0006850);; 	--	--	[S]	Function unknown	Uncharacterised protein family (UPF0041)	Mitochondrial pyruvate carrier 1 GN=MPC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitochondrial pyruvate carrier 1 [Camelus dromedarius]
ENSG00000060971(ACAA1)	--	24.237342	773	18.88004804	622	19.7334807	662	22.14437	737	23.513775	757	21.73937154	686	0.971914179	-0.099433618	normal	0.924610041	0.261375345	normal	0.974276991	0.042989441	normal	0.829904379	0.062372043	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K07513|0|ptr:460268|ACAA1; acetyl-CoA acyltransferase 1; K07513 acetyl-CoA acyltransferase 1 [EC:2.3.1.16] (A)	"Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; alpha-Linolenic acid metabolism (ko00592);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146)"	[I]	Lipid transport and metabolism	"Thiolase, N-terminal domain;; Thiolase, C-terminal domain;; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal"	"3-ketoacyl-CoA thiolase, peroxisomal (Precursor) GN=ACAA1 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: 3-ketoacyl-CoA thiolase, peroxisomal isoform 1 [Odobenus rosmarus divergens]"
ENSG00000060982(BCAT1)	--	8.071067019	878	9.05457844	1031	7.831575184	855	4.329954277	513	5.05929472	428	7.952592601	848	0.000690173	-0.804229352	normal	9.43E-11	-1.286760783	down	0.977598393	-0.02011587	normal	0.069347293	-0.647511933	normal	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K00826|0|ptr:465345|BCAT1; branched chain amino-acid transaminase 1, cytosolic; K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Valine, leucine and isoleucine biosynthesis (ko00290);; Pantothenate and CoA biosynthesis (ko00770);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Aminotransferase class IV	"Branched-chain-amino-acid aminotransferase, cytosolic GN=BCAT1 OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: branched-chain-amino-acid aminotransferase, cytosolic isoform X1 [Physeter catodon]"
ENSG00000061273(HDAC7)	--	18.72616172	1365	20.48771642	1535	18.41393727	1386	22.44907941	1555	23.39146771	1643	23.96444434	1752	0.974107523	0.157015702	normal	0.982444771	0.076594322	normal	0.885906712	0.329463644	normal	0.322515551	0.186868565	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	K11408|0|pon:100431300|HDAC7; histone deacetylase 7; K11408 histone deacetylase 7 [EC:3.5.1.98] (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain	Histone deacetylase 7 GN=HDAC7 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 7 isoform X3 [Mustela putorius furo]
ENSG00000061337(LZTS1)	--	0	0	0.02586664	3	0	0	0.035348076	4	0.045120135	4	0.011494877	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Fez1	Leucine zipper putative tumor suppressor 1 GN=LZTS1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: leucine zipper putative tumor suppressor 1 [Dasypus novemcinctus]
ENSG00000061455(PRDM6)	--	0.100585432	15	0.1362485	20	0.073521304	10	0.03415371	5	0.059710811	8	0.115473956	17	--	--	--	0.913015249	-1.196267544	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; SET domain"	Putative histone-lysine N-methyltransferase PRDM6 GN=PRDM6 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: putative histone-lysine N-methyltransferase PRDM6 [Ceratotherium simum simum]
ENSG00000061656(SPAG4)	--	7.27744	131	4.21018	81	4.34142	85	5.49205	92	3.62861	65	3.603563173	62	0.753139069	-0.533188807	normal	0.947312581	-0.331974709	normal	0.910439817	-0.453989578	normal	0.345262711	-0.462328345	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Sad1 / UNC-like C-terminal	Sperm-associated antigen 4 protein GN=SPAG4 OS=Homo sapiens (Human) PE=2 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: sperm-associated antigen 4 protein isoform 1 [Trichechus manatus latirostris]
ENSG00000061676(NCKAP1)	--	65.56797204	5851	64.82385827	5861	63.25074979	5672	46.0698881	4167	44.8683718	4040	45.98914479	4138	0.350235222	-0.520343596	normal	0.214997105	-0.558043593	normal	0.631714657	-0.463070159	normal	0.000571485	-0.51511014	normal	--	--	--	K05750|0|ptr:459801|NCKAP1; NCK-associated protein 1; K05750 NCK-associated protein 1 (A)	Regulation of actin cytoskeleton (ko04810)	[R]	General function prediction only	Membrane-associated apoptosis protein	Nck-associated protein 1 GN=NCKAP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nck-associated protein 1 isoform 2 [Sus scrofa] 
ENSG00000061794(MRPS35)	--	59.54122747	1610	60.18815782	1631	60.5394997	1621	73.17612959	2016	67.17829619	1816	64.68158021	1757	0.92799702	0.293352087	normal	0.979185942	0.133463547	normal	0.981582907	0.107841999	normal	0.342398274	0.179409854	normal	--	--	--	"K17413|0|hsa:60488|MRPS35, MDS023, MRP-S28, MRPS28; mitochondrial ribosomal protein S35; K17413 small subunit ribosomal protein S35 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal subunit protein	"28S ribosomal protein S35, mitochondrial (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S35, mitochondrial isoform X2 [Bos mutus]"
ENSG00000061918(GUCY1B3)	--	1.884944495	99	1.48826421	79	1.479111808	76	1.358278	73	1.421589985	75	1.046115807	56	0.886912849	-0.461979403	normal	0.970734519	-0.094531105	normal	0.92724585	-0.43865635	normal	0.52188675	-0.338356294	normal	[T]	Signal transduction mechanisms	Molecular Function: guanylate cyclase activity (GO:0004383);; Biological Process: cGMP biosynthetic process (GO:0006182);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Molecular Function: heme binding (GO:0020037);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12319|0|ptr:461565|GUCY1B3; guanylate cyclase 1, soluble, beta 3; K12319 guanylate cyclase soluble subunit beta [EC:4.6.1.2] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term depression (ko04730);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970)	[F]	Nucleotide transport and metabolism	Heme NO binding associated;; Adenylate and Guanylate cyclase catalytic domain;; Heme NO binding	Guanylate cyclase soluble subunit beta-1 GN=GUCY1B3 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: guanylate cyclase soluble subunit beta-1 [Galeopterus variegatus]
ENSG00000061936(SFSWAP)	--	8.737419342	667	11.0142052	801	10.19668842	779	10.05103872	759	11.16796626	810	12.21979208	922	0.963416909	0.155245473	normal	0.976496507	-0.005296948	normal	0.942704172	0.234433191	normal	0.589030441	0.128191722	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; 	--	--	[A]	RNA processing and modification	Alternative splicing regulator;; Surp module	"Splicing factor, suppressor of white-apricot homolog GN=SFSWAP OS=Homo sapiens (Human) PE=1 SV=3"	A	RNA processing and modification	"PREDICTED: splicing factor, suppressor of white-apricot homolog isoform X2 [Galeopterus variegatus]"
ENSG00000061938(TNK2)	--	7.565831535	702	7.712903308	664	8.11222196	763	9.2802651	779	7.9012053	623	6.817285721	575	0.969510845	0.119072577	normal	0.967898621	-0.113111617	normal	0.674290436	-0.415460698	normal	0.602941301	-0.128821641	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08886|0|hsa:10188|TNK2, ACK, ACK-1, ACK1, p21cdc42Hs; tyrosine kinase, non-receptor, 2 (EC:2.7.11.1 2.7.10.2); K08886 activated CDC42 kinase 1 [EC:2.7.10.2 2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; GTPase binding;; EGFR receptor inhibitor Mig-6;; Variant SH3 domain;; Kinase-like;; Variant SH3 domain	Activated CDC42 kinase 1 GN=TNK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: activated CDC42 kinase 1 [Bubalus bubalis]
ENSG00000061987(MON2)	--	14.5357397	1670	15.40382207	1820	14.456307	1650	12.98719374	1506	14.66686134	1659	15.21386839	1751	0.971567608	-0.17978431	normal	0.97679811	-0.154916235	normal	0.983552544	0.077352788	normal	0.71373972	-0.085119587	normal	--	--	--	--	--	[S]	Function unknown	Guanine nucleotide exchange factor in Golgi transport N-terminal;; Domain of unknown function (DUF1981)	Protein MON2 homolog GN=MON2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein MON2 homolog isoform X2 [Galeopterus variegatus]
ENSG00000062038(CDH3)	--	0.192491029	17	0.014418604	1	0.238700839	14	0.396826322	30	0.277692893	23	0.246106864	18	0.951041067	0.737851287	normal	0.004932115	3.272127783	up	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06796|0|hsa:1001|CDH3, CDHP, HJMD, PCAD; cadherin 3, type 1, P-cadherin (placental); K06796 cadherin 3, type 1, P-cadherin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-3 (Precursor) GN=CDH3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cadherin-3 [Vicugna pacos]
ENSG00000062194(GPBP1)	--	18.53634357	1079	20.12997105	1180	19.44037797	1113	20.76968004	1221	20.76766543	1217	21.01997618	1250	0.971930946	0.147338766	normal	0.981005891	0.023086617	normal	0.970588377	0.158979126	normal	0.633519136	0.108069009	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	--	--	--	--	Vascular protein family Vasculin-like 1	Vasculin GN=GPBP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: vasculin isoform X2 [Equus caballus] 
ENSG00000062282(DGAT2)	--	2.773166198	122	2.40586479	94	2.362736322	103	1.035891074	41	0.937275567	40	0.726090447	32	1.00E-05	-1.568248371	down	0.00923596	-1.223014559	down	2.21E-05	-1.64895485	down	5.37E-05	-1.5191311	down	--	--	"Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K11160|0|pps:100987880|DGAT2; diacylglycerol O-acyltransferase 2; K11160 diacylglycerol O-acyltransferase 2 [EC:2.3.1.20 2.3.1.75] (A)	Glycerolipid metabolism (ko00561);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Diacylglycerol acyltransferase	Diacylglycerol O-acyltransferase 2 GN=DGAT2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: diacylglycerol O-acyltransferase 2 [Tupaia chinensis]
ENSG00000062370(ZNF112)	--	4.89702637	295	4.226346328	288	4.338073219	290	3.315234012	218	3.523303833	219	5.852444216	305	0.655825474	-0.464393408	normal	0.772609853	-0.414062655	normal	0.966059623	0.064138733	normal	0.382898439	-0.254762284	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7771|ZNF112, ZFP112, ZNF228; zinc finger protein 112; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; XPA protein N-terminal"	Zinc finger protein 112 GN=ZNF112 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 112 [Felis catus]
ENSG00000062485(CS)	--	137.0274767	5107	128.8177284	4951	133.6486084	5164	195.8164678	7248	177.2576971	6599	188.0731632	6948	0.617488002	0.474154356	normal	0.877068332	0.392996614	normal	0.814233392	0.419710973	normal	0.006560172	0.428780179	normal	[C]	Energy production and conversion	"Molecular Function: transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer (GO:0046912);; "	K01647|0|hsa:1431|CS; citrate synthase (EC:2.3.3.1); K01647 citrate synthase [EC:2.3.3.1] (A)	Citrate cycle (TCA cycle) (ko00020);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[C]	Energy production and conversion	Citrate synthase	"Citrate synthase, mitochondrial (Precursor) GN=CS OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: citrate synthase, mitochondrial [Tupaia chinensis]"
ENSG00000062524(LTK)	--	0.141987023	6	0.092418062	4	0	0	0.023623228	1	0.091919341	4	0.070869662	4	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05118|0|pps:100985722|LTK; leukocyte receptor tyrosine kinase; K05118 leukocyte tyrosine kinase [EC:2.7.10.1] (A)	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Glycine rich protein	Leukocyte tyrosine kinase receptor (Precursor) GN=LTK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: leukocyte tyrosine kinase receptor isoform X2 [Oryctolagus cuniculus]
ENSG00000062582(MRPS24)	--	132.927763	1839	135.6952748	1927	136.9441041	1957	145.787166	2145	131.532584	1951	138.069294	1984	0.973168287	0.191075986	normal	0.986237617	-0.00356657	normal	0.986717844	0.011468026	normal	0.78854852	0.065904256	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; 	"K17403|5.9633e-121|hsa:64951|MRPS24, MRP-S24, S24mt, bMRP-47, bMRP47; mitochondrial ribosomal protein S24; K17403 small subunit ribosomal protein S24 (A)"	--	--	--	Mitochondrial ribosome subunit S24	"28S ribosomal protein S24, mitochondrial (Precursor) GN=MRPS24 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S24, mitochondrial [Myotis lucifugus]"
ENSG00000062598(ELMO2)	--	12.6703188	1015	10.54594989	834	11.75216644	935	11.0681796	885	9.75277358	774	11.27500651	874	0.947421605	-0.228192333	normal	0.96893214	-0.128897681	normal	0.973789547	-0.105448083	normal	0.468246626	-0.157537515	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3361);; ELMO/CED-12 family	Engulfment and cell motility protein 2 GN=ELMO2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: engulfment and cell motility protein 2 isoform X1 [Bos mutus] 
ENSG00000062650(WAPL)	--	8.98949859	1034	8.56359707	993	9.874365	1055	10.51093992	1220	10.3011769	1183	8.765324	1001	0.958295843	0.207528571	normal	0.949441813	0.230835473	normal	0.977212973	-0.083968881	normal	0.581825633	0.121702229	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Wings apart-like protein regulation of heterochromatin	Wings apart-like protein homolog GN=WAPAL OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: wings apart-like protein homolog isoform X1 [Ursus maritimus]
ENSG00000062716(VMP1)	--	134.4396045	7207	128.200559	6834	124.9809226	6616	110.8970323	6117	118.5075414	6460	104.3640674	5747	0.976939496	-0.267344882	normal	0.993286474	-0.102599284	normal	0.985886437	-0.211389737	normal	0.32482814	-0.194316684	normal	--	--	--	--	--	[R]	General function prediction only	SNARE associated Golgi protein	Vacuole membrane protein 1 GN=VMP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: vacuole membrane protein 1-like isoform X1 [Tupaia chinensis] 
ENSG00000062725(APPBP2)	--	10.47219014	988	9.84511	925	10.56177105	976	11.518856	1097	11.16696924	1051	11.320726	1068	0.974083995	0.119971214	normal	0.966679966	0.162561382	normal	0.973737914	0.121487149	normal	0.543659476	0.133465317	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat	Amyloid protein-binding protein 2 GN=APPBP2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: amyloid protein-binding protein 2 [Dasypus novemcinctus]
ENSG00000062822(POLD1)	--	32.65855301	1937	32.99041786	1895	35.46966482	2148	31.48284465	1810	29.13508173	1793	23.26670904	1530	0.981063432	-0.128560996	normal	0.982730441	-0.101165904	normal	0.356448437	-0.497336847	normal	0.162825934	-0.24177939	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	"K02327|0|hsa:5424|POLD1, CDC2, CRCS10, MDPL, POLD; polymerase (DNA directed), delta 1, catalytic subunit (EC:2.7.7.7); K02327 DNA polymerase delta subunit 1 [EC:2.7.7.7] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; HTLV-I infection (ko05166)	[L]	"Replication, recombination and repair"	"DNA polymerase family B;; DNA polymerase family B, exonuclease domain;; C4-type zinc-finger of DNA polymerase delta"	DNA polymerase delta catalytic subunit GN=POLD1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase delta catalytic subunit isoform X1 [Sus scrofa]
ENSG00000063015(SEZ6)	--	0.066886771	3	0.475406007	4	0.038345243	2	0.013223963	1	0	0	0.200311298	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sushi domain (SCR repeat);; CUB domain	Seizure protein 6 homolog (Precursor) GN=SEZ6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: seizure protein 6 homolog isoform X1 [Galeopterus variegatus]
ENSG00000063046(EIF4B)	--	198.1293076	13669	189.9501433	13711	184.928931	12725	208.4777738	14868	219.1869735	15115	235.9084685	15814	0.996705473	0.090460877	normal	0.996134206	0.119208098	normal	0.979920011	0.305212633	normal	0.447272937	0.170338545	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K03258|9.25087e-120|hsa:1975|EIF4B, EIF-4B, PRO1843; eukaryotic translation initiation factor 4B; K03258 translation initiation factor 4B (A)"	RNA transport (ko03013);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Eukaryotic translation initiation factor 4B GN=EIF4B OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4B isoform 3 [Orcinus orca]
ENSG00000063127(SLC6A16)	--	5.021211945	591	6.562452524	625	5.530178617	583	4.24174881	444	4.7907337	594	3.3241498	357	0.603025797	-0.442099543	normal	0.969147446	-0.094585021	normal	0.012931727	-0.713474014	normal	0.141252156	-0.388565758	normal	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05048|0|hsa:28968|SLC6A16, NT5, NTT5; solute carrier family 6, member 16; K05048 solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 GN=SLC6A16 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 [Canis lupus familiaris]
ENSG00000063169(GLTSCR1)	--	6.575459316	591	7.40344851	672	12.95017626	676	7.283924	544	6.396789156	534	8.626626	693	0.961437057	-0.149977178	normal	0.82845924	-0.352156836	normal	0.974918914	0.027479946	normal	0.533590558	-0.151136442	normal	--	--	--	--	--	--	--	Glioma tumor suppressor candidate region	Glioma tumor suppressor candidate region gene 1 protein GN=GLTSCR1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: glioma tumor suppressor candidate region gene 1 protein [Condylura cristata]
ENSG00000063176(SPHK2)	--	13.338439	545	16.00533	649	15.13052701	595	12.317904	499	11.11576101	454	14.58167814	609	0.959023301	-0.157584182	normal	0.271411137	-0.53545242	normal	0.973523994	0.025197813	normal	0.339659481	-0.216436268	normal	[IR]	Lipid transport and metabolism;; General function prediction only	Molecular Function: kinase activity (GO:0016301);; 	K04718|0|pps:100992056|SPHK2; sphingosine kinase 2; K04718 sphingosine kinase [EC:2.7.1.91] (A)	Sphingolipid metabolism (ko00600);; Calcium signaling pathway (ko04020);; Sphingolipid signaling pathway (ko04071);; VEGF signaling pathway (ko04370);; Fc gamma R-mediated phagocytosis (ko04666);; Tuberculosis (ko05152)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase catalytic domain	Sphingosine kinase 2 GN=SPHK2 OS=Homo sapiens (Human) PE=1 SV=2	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: sphingosine kinase 2 [Galeopterus variegatus]
ENSG00000063177(RPL18)	--	1339.980158	13067	1130.5008	11168	1243.756092	11773	1325.173384	12524	1295.824692	12657	1130.186083	10727	0.996371427	-0.092053749	normal	0.99431885	0.15911784	normal	0.994756422	-0.142507596	normal	0.940283296	-0.025630803	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02883|3.44769e-131|ptr:456183|RPL18; ribosomal protein L18; K02883 large subunit ribosomal protein L18e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L18e/L15	60S ribosomal protein L18 GN=RPL18 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	hypothetical protein PANDA_006316 [Ailuropoda melanoleuca]
ENSG00000063180(CA11)	--	10.77841945	455	8.01144808	362	11.26259	497	2.183882001	94	5.485695	225	4.757342	200	0	-2.287138999	down	0.044906019	-0.703725276	normal	2.45E-09	-1.315009002	down	1.06E-05	-1.358842133	down	[P]	Inorganic ion transport and metabolism	--	--	--	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase-related protein 11 (Precursor) GN=CA11 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carbonic anhydrase-related protein 11 isoform 2 [Canis lupus familiaris]
ENSG00000063241(ISOC2)	--	54.5360892	1013	42.94552215	823	52.28103406	1001	45.41611817	843	57.4863457	1023	35.38363853	648	0.904189433	-0.295369966	normal	0.908834617	0.291933293	normal	0.035028018	-0.63446673	normal	0.568635952	-0.195913118	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	Isochorismatase family	"Isochorismatase domain-containing protein 2, mitochondrial (Precursor) GN=ISOC2 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: isochorismatase domain-containing protein 2, mitochondrial isoform 1 [Trichechus manatus latirostris]"
ENSG00000063244(U2AF2)	--	168.7966	6101	210.7178	7897	203.0915	7322	198.2855	7247	182.9979	6316	191.7637	7123	0.986016434	0.217455608	normal	0.945517556	-0.343646319	normal	0.994850958	-0.048034166	normal	0.806688038	-0.064826686	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12837|0|mcf:102140484|U2AF2; U2 small nuclear RNA auxiliary factor 2; K12837 splicing factor U2AF 65 kDa subunit (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing factor U2AF 65 kDa subunit GN=U2AF2 OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: splicing factor U2AF 65 kDa subunit isoform X1 [Galeopterus variegatus]
ENSG00000063245(EPN1)	--	89.53750647	4316	82.86116046	4054	90.68075664	4561	93.5292149	4512	93.81305673	4538	96.32003806	4689	0.992586198	0.03322837	normal	0.988597697	0.141234147	normal	0.992845008	0.031628324	normal	0.792143684	0.06653876	normal	--	--	Molecular Function: phospholipid binding (GO:0005543);; 	K12471|0|hsa:29924|EPN1; epsin 1; K12471 epsin (A)	Endocytosis (ko04144)	[F]	Nucleotide transport and metabolism	ENTH domain;; ANTH domain	Epsin-1 GN=EPN1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: epsin-1 isoform X3 [Elephantulus edwardii]
ENSG00000063322(MED29)	--	34.385414	2097	33.62909103	2163	32.9301758	2072	38.584467	2494	37.72067	2378	35.43847	2254	0.969350149	0.219154965	normal	0.984099472	0.11521165	normal	0.984030666	0.11309291	normal	0.454583825	0.148882999	normal	--	--	Cellular Component: mediator complex (GO:0016592);; 	"K15142|4.69242e-103|hsa:55588|MED29, IXL; mediator complex subunit 29; K15142 mediator of RNA polymerase II transcription subunit 29 (A)"	--	--	--	Mediator complex subunit 29	Mediator of RNA polymerase II transcription subunit 29 GN=MED29 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 29 [Orcinus orca]
ENSG00000063438(AHRR)	--	76.00757684	1742	78.51843245	1695	84.4360765	1801	76.14056404	1470	74.51522129	1443	77.30690592	1463	0.936451345	-0.275495825	normal	0.948680291	-0.253395195	normal	0.911718238	-0.307872479	normal	0.093211845	-0.280520359	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09094|0|hsa:57491|AHRR, AHH, AHHR, bHLHe77; aryl-hydrocarbon receptor repressor; K09094 aryl hydrocarbon receptor repressor (A)"	--	[K]	Transcription	PAS fold;; Helix-loop-helix DNA-binding domain	Aryl hydrocarbon receptor repressor GN=AHRR OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: aryl hydrocarbon receptor repressor [Ceratotherium simum simum]
ENSG00000063587(ZNF275)	--	4.046073399	438	2.83677524	307	2.919218836	314	3.907232034	421	5.157603381	555	3.549228669	384	0.966720944	-0.087629326	normal	0.001383954	0.829740655	normal	0.909508757	0.280825343	normal	0.363627571	0.339418858	normal	[R]	General function prediction only	--	K09228|0|ptr:473827|ZNF275; zinc finger protein 275; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 275 GN=ZNF275 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 275 [Ceratotherium simum simum]
ENSG00000063601(MTMR1)	--	10.73146875	767	10.1270106	772	10.95604622	794	13.05723199	971	12.65778001	951	11.451133	864	0.888977914	0.308861536	normal	0.917394055	0.278924889	normal	0.971801257	0.113393769	normal	0.22455537	0.234545274	normal	--	--	--	K18081|0|pon:100443993|MTMR1; myotubularin related protein 1; K18081 myotubularin-related protein 1/2 [EC:3.1.3.-] (A)	--	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	Myotubularin-like phosphatase domain;; GRAM domain	Myotubularin-related protein 1 GN=MTMR1 OS=Homo sapiens (Human) PE=1 SV=4	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: myotubularin-related protein 1 [Oryctolagus cuniculus]
ENSG00000063660(GPC1)	--	119.3917948	7920	120.4523714	8563	123.8559241	8271	52.18263162	3373	54.21405906	3154	46.17129093	3242	1.35E-12	-1.261913191	down	2.22E-16	-1.461916383	down	1.01E-14	-1.359057376	down	4.39E-23	-1.362719792	down	--	--	Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Cellular Component: membrane (GO:0016020);; Molecular Function: heparan sulfate proteoglycan binding (GO:0043395);; 	"K08107|0|hsa:2817|GPC1, glypican; glypican 1; K08107 glypican 1 (A)"	Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Glypican	Secreted glypican-1 (Precursor) GN=GPC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: glypican-1 [Ceratotherium simum simum]
ENSG00000063761(ADCK1)	--	2.609768087	102	3.058791204	122	2.6917276	103	2.48677686	101	3.312340495	131	4.84177962	172	0.970444825	-0.044374399	normal	0.965733825	0.080298444	normal	0.195798517	0.723169937	normal	0.522028729	0.285283578	normal	[R]	General function prediction only	--	K08869|0|pps:100968758|ADCK1; aarF domain containing kinase 1; K08869 aarF domain-containing kinase (A)	--	[R]	General function prediction only	ABC1 family;; Protein kinase domain	Uncharacterized aarF domain-containing protein kinase 1 (Precursor) GN=ADCK1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: uncharacterized aarF domain-containing protein kinase 1 [Ceratotherium simum simum]
ENSG00000063854(HAGH)	--	33.89329746	752	31.80554209	806	35.03468495	827	29.78351365	720	30.36989336	694	35.17384498	830	0.97214545	-0.093373024	normal	0.939181922	-0.23679141	normal	0.977434059	-0.003061846	normal	0.659065622	-0.108611968	normal	[R]	General function prediction only	--	"K01069|0|ptr:453828|HAGH; hydroxyacylglutathione hydrolase, mitochondrial; K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6] (A)"	Pyruvate metabolism (ko00620)	[R]	General function prediction only	Metallo-beta-lactamase superfamily	"Hydroxyacylglutathione hydrolase, mitochondrial (Precursor) GN=HAGH OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: hydroxyacylglutathione hydrolase, mitochondrial [Camelus bactrianus]"
ENSG00000063978(RNF4)	--	26.70440654	1489	25.28159387	1457	28.04607374	1609	30.694426	1735	31.76729449	1813	24.24725835	1373	0.969790412	0.1895783	normal	0.925740496	0.293677764	normal	0.95420256	-0.236882852	normal	0.702729371	0.089884772	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	E3 ubiquitin-protein ligase RNF4 GN=RNF4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF4 isoform X1 [Tupaia chinensis] 
ENSG00000064012(CASP8)	--	18.77605953	952	17.5048079	905	18.75346026	898	12.3243545	636	12.75535981	622	13.22354465	670	0.056792046	-0.61155051	normal	0.162486149	-0.561291284	normal	0.621617059	-0.430004326	normal	0.000904498	-0.536042893	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K04398|0|ptr:746477|CASP8; caspase 8, apoptosis-related cysteine peptidase; K04398 caspase 8 [EC:3.4.22.61] (A)"	p53 signaling pathway (ko04115);; Apoptosis (ko04210);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; TNF signaling pathway (ko04668);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Huntington's disease (ko05016);; Legionellosis (ko05134);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Viral myocarditis (ko05416)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Death effector domain;; Caspase domain	Caspase-8 subunit p10 (Precursor) GN=CASP8 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-8 [Galeopterus variegatus]
ENSG00000064042(LIMCH1)	--	36.05687615	3379	32.12848389	2831	32.63753674	3131	26.1007881	2572	23.04197613	2461	22.28338064	2574	0.72001725	-0.424316036	normal	0.971126601	-0.22336555	normal	0.945876865	-0.290747752	normal	0.047899051	-0.317401659	normal	--	--	--	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	LIM domain	LIM and calponin homology domains-containing protein 1 GN=LIMCH1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: LIM and calponin homology domains-containing protein 1 isoform X2 [Panthera tigris altaica]
ENSG00000064102(INTS13)	--	12.1876163	668	13.89202916	720	15.50499257	869	16.1689025	899	13.12272427	720	11.13616594	654	0.72528915	0.396851471	normal	0.974982676	-0.021381649	normal	0.664436562	-0.417516513	normal	0.984925516	-0.011616991	normal	--	--	--	--	--	[S]	Function unknown	Cell cycle and development regulator	Protein asunder homolog GN=ASUN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein asunder homolog isoform X1 [Eptesicus fuscus]
ENSG00000064115(TM7SF3)	--	69.64727069	3207	84.3884886	3312	73.77950406	3074	98.7499613	4152	83.04754074	3787	92.33290739	4063	0.914543256	0.34160566	normal	0.98411717	0.171852766	normal	0.826509017	0.393967648	normal	0.066518832	0.301817749	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4203)	Transmembrane 7 superfamily member 3 (Precursor) GN=TM7SF3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane 7 superfamily member 3 isoform X1 [Equus caballus] 
ENSG00000064195(DLX3)	--	0.0201923	1	0	0	0	0	0.0204498	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09315|0|ecb:100146218|DLX3; distal-less homeobox 3; K09315 homeobox protein DLX3 (A)	--	[K]	Transcription	Homeobox protein distal-less-like N terminal;; Homeobox domain	Homeobox protein DLX-3 GN=DLX3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox protein DLX-3 [Equus caballus]
ENSG00000064199(SPA17)	--	9.4404611	284	7.77375	259	10.54886	283	10.36749	329	10.4669807	307	9.7053688	279	0.950771841	0.180456777	normal	0.938164264	0.222664674	normal	0.967242081	-0.028674049	normal	0.714667738	0.126043105	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Regulatory subunit of type II PKA R-subunit;; IQ calmodulin-binding motif	Sperm surface protein Sp17 GN=SPA17 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: sperm surface protein Sp17 isoform X2 [Tupaia chinensis]
ENSG00000064205(WISP2)	--	27.434134	658	19.770988	479	19.951199	493	15.96905	385	17.064216	405	11.432063	276	0.00132861	-0.801582957	normal	0.919249251	-0.262627348	normal	0.001155311	-0.841710887	normal	0.028427221	-0.634861804	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Insulin-like growth factor binding protein;; von Willebrand factor type C domain;; Thrombospondin type 1 domain	WNT1-inducible-signaling pathway protein 2 (Precursor) GN=WISP2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: WNT1-inducible-signaling pathway protein 2 [Myotis lucifugus]
ENSG00000064225(ST3GAL6)	--	1.419727309	61	1.605404662	63	1.80032524	54	1.000250066	54	0.70708252	37	0.87903694	29	0.972037698	-0.201289316	normal	0.7368971	-0.7650099	normal	0.702989747	-0.871389816	normal	0.276762493	-0.592242789	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03792|0|mcc:699096|ST3GAL6; ST3 beta-galactoside alpha-2,3-sialyltransferase 6; K03792 beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 10) [EC:2.4.99.10] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Type 2 lactosamine alpha-2,3-sialyltransferase GN=ST3GAL6 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: type 2 lactosamine alpha-2,3-sialyltransferase isoform X1 [Oryctolagus cuniculus]"
ENSG00000064270(ATP2C2)	--	0.960764389	36	0.666649143	26	0.440184493	20	0.414391373	13	0.46654295	17	0.2247225	12	0.355924246	-1.397188056	normal	0.970733128	-0.591555519	normal	0.977463343	-0.678425031	normal	0.142216973	-0.987120707	normal	[P]	Inorganic ion transport and metabolism	--	"K01537|0|hsa:9914|ATP2C2, SPCA2; ATPase, Ca++ transporting, type 2C, member 2 (EC:3.6.3.8); K01537 Ca2+-transporting ATPase [EC:3.6.3.8] (A)"	--	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase"	Calcium-transporting ATPase type 2C member 2 GN=ATP2C2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: calcium-transporting ATPase type 2C member 2 [Ceratotherium simum simum]
ENSG00000064300(NGFR)	--	0.161815366	12	0.081411335	5	0.077917225	2	0.08153538	6	0.065433649	4	0.05346216	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K02583|0|pps:100969001|NGFR; nerve growth factor receptor; K02583 nerve growth factor receptor (TNFR superfamily member 16) (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Neurotrophin signaling pathway (ko04722);; Transcriptional misregulation in cancer (ko05202)	--	--	TNFR/NGFR cysteine-rich region;; Death domain	Tumor necrosis factor receptor superfamily member 16 (Precursor) GN=NGFR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 16 [Condylura cristata]
ENSG00000064309(CDON)	--	5.210020069	348	5.767043031	287	4.274228994	324	3.13603518	194	4.184678344	210	2.874563359	158	0.001997383	-0.868648618	normal	0.65565312	-0.469185088	normal	7.80E-05	-1.037277315	down	0.000466002	-0.79256575	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Cell adhesion molecule-related/down-regulated by oncogenes (Precursor) GN=CDON OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cell adhesion molecule-related/down-regulated by oncogenes [Ceratotherium simum simum]
ENSG00000064313(TAF2)	--	13.462462	1097	13.35620107	1131	12.83162796	1076	15.12635545	1253	14.385587	1214	14.712364	1263	0.970078535	0.160779821	normal	0.978580041	0.080638851	normal	0.954167504	0.222596069	normal	0.457053557	0.153716111	normal	--	--	--	"K03128|0|hsa:6873|TAF2, CIF150, MRT40, TAF2B, TAFII150; TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa; K03128 transcription initiation factor TFIID subunit 2 (A)"	Basal transcription factors (ko03022)	[K]	Transcription	Peptidase family M1;; HEAT repeats	Transcription initiation factor TFIID subunit 2 GN=TAF2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 2 [Camelus ferus] 
ENSG00000064393(HIPK2)	--	12.57543347	3657	10.9841136	3257	12.91707831	3731	10.67871777	3162	11.01123072	3201	8.693038027	2545	0.971467004	-0.240546714	normal	0.990070918	-0.046425856	normal	0.150972271	-0.559911631	normal	0.096896626	-0.278601973	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K08826|0|ptr:463772|HIPK2; homeodomain interacting protein kinase 2; K08826 homeodomain interacting protein kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Homeodomain-interacting protein kinase 2 GN=HIPK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: homeodomain-interacting protein kinase 2 isoform X1 [Ochotona princeps]
ENSG00000064419(TNPO3)	--	32.87870199	2432	32.28137844	2368	34.60743981	2561	32.97301806	2460	33.03110461	2402	36.26520422	2669	0.98859388	-0.014308189	normal	0.988107657	-0.000858943	normal	0.988592807	0.051270952	normal	0.972572149	0.012100168	normal	--	--	--	K15436|0|cfr:102520691|TNPO3; transportin 3; K15436 transportin-3 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exportin 1-like protein	Transportin-3 GN=TNPO3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transportin-3 isoform X1 [Camelus ferus]
ENSG00000064489(BORCS8-MEF2B)	--	9.711287	244	8.7574807	225	8.444137	206	8.375809542	199	9.0917202	222	7.917708	204	0.893694283	-0.32269037	normal	0.965222287	-0.040517716	normal	0.966812167	-0.022202834	normal	0.737214087	-0.132302525	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein dimerization activity (GO:0046983);; 	"K09261|9.31824e-159|hsa:4207|MEF2BNB-MEF2B, LOC729991-MEF2B, MEF2B; MEF2BNB-MEF2B readthrough; K09261 MADS-box transcription enhancer factor 2B (A)"	cGMP-PKG signaling pathway (ko04022)	[K]	Transcription	SRF-type transcription factor (DNA-binding and dimerisation domain)	Myocyte-specific enhancer factor 2B GN=MEF2B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: myocyte-specific enhancer factor 2B-like [Camelus bactrianus] 
ENSG00000064490(RFXANK)	--	21.58357973	399	18.50712938	359	17.21462034	356	17.6198418	349	17.93420809	350	18.92490512	370	0.938123486	-0.223074614	normal	0.966440106	-0.057808839	normal	0.968063587	0.04716007	normal	0.818502798	-0.080593389	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K08062|0|pps:100992419|RFXANK; regulatory factor X-associated ankyrin-containing protein; K08062 regulatory factor X-associated ankyrin-containing protein (A)	Antigen processing and presentation (ko04612);; Tuberculosis (ko05152);; Primary immunodeficiency (ko05340)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	DNA-binding protein RFXANK GN=RFXANK OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-binding protein RFXANK [Galeopterus variegatus]
ENSG00000064545(TMEM161A)	--	17.19157317	472	14.94533355	438	19.05577883	510	15.73313291	443	18.73406336	501	15.33733313	424	0.963564934	-0.121902719	normal	0.954240529	0.171897918	normal	0.912557645	-0.273832554	normal	0.816805819	-0.074837869	normal	--	--	--	--	--	[S]	Function unknown	Predicted transmembrane protein 161AB	Transmembrane protein 161A (Precursor) GN=TMEM161A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 161A isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000064547(LPAR2)	--	6.116448851	290	4.826715118	242	5.367395231	278	5.986147355	289	6.553298189	340	4.960439038	288	0.967103291	-0.035626594	normal	0.629001628	0.466630325	normal	0.966854799	0.042465518	normal	0.628904125	0.158005969	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04291|0|hsa:9170|LPAR2, EDG-4, EDG4, LPA-2, LPA2; lysophosphatidic acid receptor 2; K04291 lysophosphatidic acid receptor 2 (A)"	Rap1 signaling pathway (ko04015);; Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Lysophosphatidic acid receptor 2 GN=LPAR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: lysophosphatidic acid receptor 2 [Myotis lucifugus]
ENSG00000064601(CTSA)	--	80.06571	2783	82.92092	2916	75.827699	2679	77.041822	2598	76.415698	2590	102.171679	3599	0.985142328	-0.129997438	normal	0.978041008	-0.192359251	normal	0.74972218	0.41740608	normal	0.903323627	0.048418508	normal	--	--	Molecular Function: serine-type carboxypeptidase activity (GO:0004185);; Biological Process: proteolysis (GO:0006508);; 	"K13289|0|hsa:5476|CTSA, GLB2, GSL, NGBE, PPCA, PPGB; cathepsin A (EC:3.4.16.5); K13289 cathepsin A (carboxypeptidase C) [EC:3.4.16.5] (A)"	Lysosome (ko04142);; Renin-angiotensin system (ko04614)	[OE]	"Posttranslational modification, protein turnover, chaperones;; Amino acid transport and metabolism"	Serine carboxypeptidase	Lysosomal protective protein 20 kDa chain (Precursor) GN=CTSA OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: lysosomal protective protein [Pteropus alecto] 
ENSG00000064607(SUGP2)	--	16.20301661	2042	16.09608581	2032	16.42732392	2121	17.40100916	2239	16.97863386	2174	19.38869872	2647	0.984637165	0.101966117	normal	0.98547685	0.075970313	normal	0.924258887	0.311123175	normal	0.383449708	0.167925921	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; 	"K13166|0|hsa:10147|SUGP2, SFRS14; SURP and G patch domain containing 2; K13166 splicing factor, arginine/serine-rich 14 (A)"	--	[R]	General function prediction only	Surp module;; G-patch domain	SURP and G-patch domain-containing protein 2 GN=SUGP2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: SURP and G-patch domain-containing protein 2 isoform X1 [Physeter catodon] 
ENSG00000064651(SLC12A2)	--	29.39318034	3020	34.37046065	3638	25.81905166	2636	14.464734	1544	20.1948921	2140	18.53071606	1959	2.55E-07	-0.997983753	normal	0.000542402	-0.78652972	normal	0.648744727	-0.436232998	normal	0.002383156	-0.74068727	normal	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Biological Process: ion transport (GO:0006811);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K10951|0|nle:100587696|SLC12A2; solute carrier family 12 (sodium/potassium/chloride transporters), member 2; K10951 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 (A)"	Salivary secretion (ko04970);; Pancreatic secretion (ko04972)	[P]	Inorganic ion transport and metabolism	Amino acid permease;; Amino acid permease N-terminal;; Amino acid permease	Solute carrier family 12 member 2 GN=SLC12A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 12 member 2 isoform X1 [Bos taurus]
ENSG00000064652(SNX24)	--	23.60160523	419	30.78998802	435	25.31429194	469	29.34901673	513	28.09779148	446	21.01030045	385	0.920806361	0.260312504	normal	0.969689378	0.014551791	normal	0.899334698	-0.291980016	normal	1	0.000821734	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17941|1.93693e-113|ssc:100526158|SNX24; sorting nexin 24; K17941 sorting nexin-22/24 (A)	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	PX domain	Sorting nexin-24 GN=SNX24 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-24 [Odobenus rosmarus divergens]
ENSG00000064655(EYA2)	--	5.6554699	268	4.68578904	216	5.403518485	232	2.367804234	130	2.878755587	144	2.682916036	134	0.000116872	-1.065581905	down	0.382544439	-0.601196646	normal	0.033722406	-0.793293118	normal	0.001420594	-0.832470481	normal	--	--	--	"K17620|0|hsa:2139|EYA2, EAB1; EYA transcriptional coactivator and phosphatase 2 (EC:3.1.3.48); K17620 eyes absent homolog 2 [EC:3.1.3.48] (A)"	--	[R]	General function prediction only	--	Eyes absent homolog 2 GN=EYA2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: eyes absent homolog 2 isoform X1 [Galeopterus variegatus]
ENSG00000064666(CNN2)	--	50.55034206	1827	46.11962933	1732	59.54487707	2209	86.62303342	3223	73.14670807	2569	49.2273676	1803	0.00038363	0.787590417	normal	0.195454324	0.546946936	normal	0.925872782	-0.301056918	normal	0.381492324	0.37450061	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Calponin family repeat;; Calponin homology (CH) domain	Calponin-2 GN=CNN2 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: calponin-2 isoform X1 [Galeopterus variegatus]
ENSG00000064687(ABCA7)	--	4.7641147	544	4.40542344	536	4.003892863	471	5.280852891	491	4.79027361	526	4.38365986	515	0.954314854	-0.178185847	normal	0.970651678	-0.048458739	normal	0.964654875	0.120184788	normal	0.910151281	-0.039036528	normal	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05645|0|hsa:10347|ABCA7, ABCA-SSN, ABCX; ATP-binding cassette, sub-family A (ABC1), member 7; K05645 ATP-binding cassette, subfamily A (ABC1), member 7 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC-2 family transporter protein;; ABC transporter;; AAA domain	ATP-binding cassette sub-family A member 7 GN=ABCA7 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 7 [Galeopterus variegatus]
ENSG00000064692(SNCAIP)	--	0.076626358	3	0.015558057	1	0	0	0.058013221	2	0.028115422	0	0.024221513	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K04558|0|pps:100976642|SNCAIP; synuclein, alpha interacting protein; K04558 synuclein, alpha interacting protein (synphilin) (A)"	Parkinson's disease (ko05012)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Synphilin-1 GN=SNCAIP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: synphilin-1 isoform 1 [Ceratotherium simum simum]
ENSG00000064703(DDX20)	--	6.985813	493	6.5642503	460	6.153885	428	5.878375	415	6.2916774	441	5.719656	404	0.908981041	-0.278361601	normal	0.9668911	-0.082006384	normal	0.966249179	-0.091215159	normal	0.578036869	-0.153690348	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K13131|0|hsa:11218|DDX20, DP103, GEMIN3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 20 (EC:3.6.4.13); K13131 ATP-dependent RNA helicase DDX20 [EC:3.6.4.13] (A)"	RNA transport (ko03013)	[K]	Transcription	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX20 GN=DDX20 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX20 [Leptonychotes weddellii]
ENSG00000064726(BTBD1)	--	46.51146252	2335	48.03902374	2438	48.41671489	2417	52.87226	2685	46.693837	2343	42.63521299	2147	0.98008677	0.170562556	normal	0.986622383	-0.078717916	normal	0.977515778	-0.179067771	normal	0.935148958	-0.024886449	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10477|0|pon:100448977|BTBD1; BTB (POZ) domain containing 1; K10477 BTB/POZ domain-containing protein 1/2 (A)	--	[S]	Function unknown	PHR domain;; BTB/POZ domain;; BTB And C-terminal Kelch	BTB/POZ domain-containing protein 1 GN=BTBD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 1 [Orcinus orca]
ENSG00000064763(FAR2)	--	0.980531956	45	1.03012726	45	1.281706	50	0.779202	33	0.531382	29	0.676538005	38	0.959409506	-0.459878593	normal	0.92244013	-0.628768823	normal	0.962344452	-0.390626291	normal	0.420002806	-0.506058407	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K13356|0|hsa:55711|FAR2, MLSTD1, SDR10E2; fatty acyl CoA reductase 2 (EC:1.2.1.n2); K13356 fatty acyl-CoA reductase [EC:1.2.1.-] (A)"	Peroxisome (ko04146)	[I]	Lipid transport and metabolism	"Male sterility protein;; Male sterility protein;; NAD dependent epimerase/dehydratase family;; 3-beta hydroxysteroid dehydrogenase/isomerase family;; RmlD substrate binding domain;; Polysaccharide biosynthesis protein;; Semialdehyde dehydrogenase, NAD binding domain"	Fatty acyl-CoA reductase 2 GN=FAR2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: fatty acyl-CoA reductase 2 [Felis catus]
ENSG00000064787(BCAS1)	--	0.096024781	7	0.204758582	18	0.03210416	2	0.180171821	16	0.518241245	32	0.329645412	27	--	--	--	0.93555297	0.760194519	normal	0.002461918	3.014815102	up	--	--	--	--	--	--	--	--	--	--	--	Breast carcinoma-amplified sequence 1 GN=BCAS1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: breast carcinoma-amplified sequence 1 [Ceratotherium simum simum]
ENSG00000064835(POU1F1)	--	0	0	0	0	0	0	0	0	0.085335574	1	0.043841242	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09363|0|ptr:470861|POU1F1; POU class 1 homeobox 1; K09363 POU domain transcription factor, class 1 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	Pituitary-specific positive transcription factor 1 GN=POU1F1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: pituitary-specific positive transcription factor 1 isoform X1 [Mustela putorius furo]
ENSG00000064886(CHI3L2)	--	0	0	0.092015	1	0	0	0.0405134	1	0	0	0.088626229	2	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; 	K17523|0|ptr:457115|CHI3L2; chitinase 3-like 2; K17523 chitinase-3-like protein 1/2 (A)	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 18	Chitinase-3-like protein 2 (Precursor) GN=CHI3L2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: chitinase-3-like protein 2 [Galeopterus variegatus]
ENSG00000064932(SBNO2)	--	21.66072565	1745	21.76885607	1726	20.51908114	1762	17.43179096	1584	17.79397897	1519	20.9617016	1842	0.974044925	-0.170329469	normal	0.966123267	-0.205545021	normal	0.985034431	0.055720918	normal	0.641794841	-0.102403214	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[KT]	Transcription;; Signal transduction mechanisms	"P-loop containing NTP hydrolase pore-1;; Helicase_C-like;; Type III restriction enzyme, res subunit"	Protein strawberry notch homolog 2 GN=SBNO2 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: protein strawberry notch homolog 2 [Galeopterus variegatus]
ENSG00000064933(PMS1)	--	10.68501057	477	13.280463	596	13.319286	611	7.380438187	367	5.841579638	273	6.45190084	302	0.723815522	-0.407539974	normal	2.21E-07	-1.143438072	down	5.22E-06	-1.021244409	down	4.89E-06	-0.859814885	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	"K10864|0|hsa:5378|PMS1, HNPCC3, PMSL1, hPMS1; PMS1 postmeiotic segregation increased 1 (S. cerevisiae); K10864 DNA mismatch repair protein PMS1 (A)"	--	[L]	"Replication, recombination and repair"	"DNA mismatch repair protein, C-terminal domain;; HMG (high mobility group) box;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; HMG-box domain"	PMS1 protein homolog 1 GN=PMS1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: PMS1 protein homolog 1 isoform X4 [Galeopterus variegatus]
ENSG00000064961(HMG20B)	--	46.90993359	1305	35.30611741	995	37.48047951	1106	29.11704809	853	42.86532206	1120	31.21952793	889	0.024010402	-0.643319838	normal	0.970059146	0.149090073	normal	0.876727942	-0.322894022	normal	0.287492507	-0.272006195	normal	--	--	--	--	--	[R]	General function prediction only	HMG (high mobility group) box;; HMG-box domain	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related GN=HMG20B OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related isoform X2 [Balaenoptera acutorostrata scammoni] 
ENSG00000064989(CALCRL)	--	0.41680904	20	0.102215007	6	0.10491662	6	0.150782494	7	0.04052779	2	0.554664173	12	0.871727385	-1.362029351	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	K04577|0|ptr:459810|CALCRL; calcitonin receptor-like; K04577 calcitonin receptor-like (A)	Neuroactive ligand-receptor interaction (ko04080);; Vascular smooth muscle contraction (ko04270)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Calcitonin gene-related peptide type 1 receptor (Precursor) GN=CALCRL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcitonin gene-related peptide type 1 receptor [Ochotona princeps]
ENSG00000064995(TAF11)	--	8.069066118	231	9.820836661	282	7.497970005	213	9.335698488	268	8.597645	244	8.466532	242	0.950835684	0.182380955	normal	0.936554141	-0.228919454	normal	0.952938729	0.174697813	normal	0.949356766	0.032706623	normal	[K]	Transcription	Cellular Component: nucleus (GO:0005634);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	"K03135|5.10242e-121|pps:100971864|TAF11; TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa; K03135 transcription initiation factor TFIID subunit 11 (A)"	Basal transcription factors (ko03022)	[K]	Transcription	hTAFII28-like protein conserved region;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Transcription initiation factor TFIID subunit 11 GN=TAF11 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 11 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000064999(ANKS1A)	--	4.092526	505	5.184800067	635	4.24582794	522	4.990222286	595	4.480144745	538	4.280219577	556	0.947128399	0.205198394	normal	0.923071883	-0.259903621	normal	0.969499319	0.082511982	normal	1	0.001615251	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; Phosphotyrosine interaction domain (PTB/PID);; SAM domain (Sterile alpha motif)	Ankyrin repeat and SAM domain-containing protein 1A GN=ANKS1A OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: ankyrin repeat and SAM domain-containing protein 1A isoform 2 [Ceratotherium simum simum]
ENSG00000065000(AP3D1)	--	30.44507363	3404	32.10418948	3688	30.329961	3498	32.15322147	3774	32.67453517	3881	31.69381346	3735	0.988675732	0.117980536	normal	0.991091	0.052142376	normal	0.990121872	0.08625042	normal	0.721808438	0.083824564	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; 	"K12396|0|hsa:8943|AP3D1, ADTD, hBLVR; adaptor-related protein complex 3, delta 1 subunit; K12396 AP-3 complex subunit delta-1 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptin N terminal region;; Bovine leukaemia virus receptor (BLVR);; non-SMC mitotic condensation complex subunit 1;; HEAT repeat;; HEAT repeats	AP-3 complex subunit delta-1 GN=AP3D1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-3 complex subunit delta-1 [Ceratotherium simum simum]
ENSG00000065029(ZNF76)	--	4.570987012	256	4.423740164	238	4.836404201	253	3.472423106	183	4.018519558	198	5.61159926	287	0.567746172	-0.511482706	normal	0.916304986	-0.284899778	normal	0.952695983	0.172652375	normal	0.617425616	-0.181042608	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 76 GN=ZNF76 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 76 isoform X1 [Tupaia chinensis] 
ENSG00000065054(SLC9A3R2)	--	33.80179004	1046	28.57878	888	31.18280016	954	31.67265901	939	32.13670623	1057	23.983348	737	0.961900274	-0.186229149	normal	0.947511239	0.229558538	normal	0.77020977	-0.379928892	normal	0.738250507	-0.101317549	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13358|0|hsa:9351|SLC9A3R2, E3KARP, NHE3RF2, NHERF-2, NHERF2, OCTS2, SIP-1, SIP1, TKA-1; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2; K13358 Na(+)/H(+) exchange regulatory cofactor NHE-RF2 (A)"	Aldosterone-regulated sodium reabsorption (ko04960)	[S]	Function unknown	"PDZ domain (Also known as DHR or GLGF);; EBP50, C-terminal;; PDZ domain"	Na(+)/H(+) exchange regulatory cofactor NHE-RF2 GN=SLC9A3R2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF2 isoform 4 [Orcinus orca]
ENSG00000065057(NTHL1)	--	21.832867	437	21.755912	453	20.823921	432	18.756829	379	18.9805833	374	16.2392069	322	0.933216367	-0.235378106	normal	0.895619834	-0.296806947	normal	0.678300832	-0.430509976	normal	0.166917219	-0.320083974	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Biological Process: base-excision repair (GO:0006284);; 	"K10773|0|hsa:4913|NTHL1, NTH1, OCTS3, hNTH1; nth endonuclease III-like 1 (E. coli) (EC:4.2.99.18); K10773 endonuclease III [EC:4.2.99.18] (A)"	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	HhH-GPD superfamily base excision DNA repair protein;; Helix-hairpin-helix motif	Endonuclease III-like protein 1 {ECO:0000255|HAMAP-Rule:MF_03183} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: endonuclease III-like protein 1 [Camelus bactrianus]
ENSG00000065060(UHRF1BP1)	--	6.3728745	1161	6.399926	1149	5.988681918	1087	5.312272	956	4.954241	891	7.538074	1356	0.892551295	-0.310663785	normal	0.763685845	-0.387726778	normal	0.898234473	0.310326499	normal	0.787338393	-0.105106376	normal	--	--	--	--	--	[S]	Function unknown	"N-terminal region of Chorein, a TM vesicle-mediated sorter"	UHRF1-binding protein 1 GN=UHRF1BP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UHRF1-binding protein 1 [Ursus maritimus]
ENSG00000065135(GNAI3)	--	45.50987355	2624	45.12291077	2333	51.31381507	2576	50.14899677	2589	47.1593738	2504	44.98594494	2189	0.988598727	-0.05017544	normal	0.986649291	0.080571279	normal	0.96300022	-0.242997145	normal	0.772376546	-0.070460562	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04630|0|ptr:457093|GNAI3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; K04630 guanine nucleotide-binding protein G(i) subunit alpha (A)"	Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Axon guidance (ko04360);; Tight junction (ko04530);; Gap junction (ko04540);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pertussis (ko05133);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Guanine nucleotide-binding protein G(k) subunit alpha GN=GNAI3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(k) subunit alpha [Equus caballus] 
ENSG00000065150(IPO5)	--	59.67944203	4958	55.0911486	4678	62.21104804	5129	66.22911371	5612	58.98122595	4985	52.89500514	4446	0.990099564	0.147881382	normal	0.992285489	0.070253083	normal	0.982407051	-0.214393107	normal	0.987079908	0.00513636	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	HEAT repeats;; HEAT repeat;; HEAT-like repeat;; Vacuolar 14 Fab1-binding region;; Armadillo/beta-catenin-like repeat;; Importin-beta N-terminal domain	Importin-5 GN=IPO5 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin-5 isoform X1 [Leptonychotes weddellii] 
ENSG00000065154(OAT)	--	40.72391548	1204	34.798924	1039	43.250508	1271	55.776	1659	50.52281022	1483	45.35197	1336	0.628964891	0.431175757	normal	0.393308192	0.491294958	normal	0.98122011	0.06359073	normal	0.043517504	0.328147591	normal	[E]	Amino acid transport and metabolism	Molecular Function: transaminase activity (GO:0008483);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	K00819|0|ptr:450803|OAT; ornithine aminotransferase; K00819 ornithine--oxo-acid transaminase [EC:2.6.1.13] (A)	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	Aminotransferase class-III	"Ornithine aminotransferase, renal form (Precursor) GN=OAT OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: ornithine aminotransferase, mitochondrial [Dasypus novemcinctus]"
ENSG00000065183(WDR3)	--	7.273341332	1102	7.080260001	973	7.255325044	1135	8.59924068	1130	7.853608075	1076	6.896337309	889	0.980798223	0.005358907	normal	0.973042138	0.123557143	normal	0.817586519	-0.360184744	normal	0.771780409	-0.074311927	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14556|0|hsa:10885|WDR3, DIP2, UTP12; WD repeat domain 3; K14556 U3 small nucleolar RNA-associated protein 12 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	"WD domain, G-beta repeat;; Dip2/Utp12 Family;; Nup133 N terminal like"	WD repeat-containing protein 3 GN=WDR3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: WD repeat-containing protein 3 [Oryctolagus cuniculus]
ENSG00000065243(PKN2)	--	11.80113391	1102	12.7170709	1148	14.37823457	1210	15.75642688	1419	14.27378305	1285	15.59254575	1380	0.87036307	0.333507433	normal	0.973354945	0.141043478	normal	0.96785498	0.181157628	normal	0.23372106	0.218020384	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; 	"K06071|0|hsa:5586|PKN2, PAK2, PRK2, PRKCL2, PRO2042, Pak-2, STK7; protein kinase N2 (EC:2.7.11.13); K06071 protein kinase N [EC:2.7.11.13] (A)"	PI3K-Akt signaling pathway (ko04151);; Salmonella infection (ko05132)	[T]	Signal transduction mechanisms	Protein kinase domain;; Hr1 repeat;; Protein tyrosine kinase;; Protein kinase C terminal domain;; Up-regulated During Septation;; Kinase-like	Serine/threonine-protein kinase N2 GN=PKN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase N2 isoform X1 [Tupaia chinensis]
ENSG00000065268(WDR18)	--	23.94047519	703	20.21978162	709	23.11321211	721	23.83668113	719	26.1066874	777	25.44949855	796	0.975571782	0.001631293	normal	0.97006412	0.110477265	normal	0.967940326	0.13420972	normal	0.758670418	0.082895114	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14829|0|hsa:57418|WDR18, Ipi3, R32184_1; WD repeat domain 18; K14829 pre-rRNA-processing protein IPI3 (A)"	--	[R]	General function prediction only	"Alternative WD40 repeat motif;; WD domain, G-beta repeat"	WD repeat-containing protein 18 GN=WDR18 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 18 [Orcinus orca]
ENSG00000065308(TRAM2)	--	19.38566	2293	18.05972	2138	18.98101	2235	22.75198	2679	19.77924	2330	19.52756	2325	0.976358693	0.193505921	normal	0.984746699	0.102572032	normal	0.987473911	0.048632178	normal	0.583102064	0.116147175	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TRAM1-like protein;; TLC domain	Translocating chain-associated membrane protein 2 GN=TRAM2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: translocating chain-associated membrane protein 2 isoform 2 [Dasypus novemcinctus]
ENSG00000065320(NTN1)	--	0.397237065	45	0.445072382	52	0.335521246	39	0.396756955	46	0.500593	57	0.796581	92	0.980328494	0.000847961	normal	0.975212348	0.108022506	normal	0.014613364	1.198726742	normal	0.420421565	0.500344529	normal	--	--	--	"K06843|0|hsa:9423|NTN1, NTN1L; netrin 1; K06843 netrin 1 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Laminin N-terminal (Domain VI);; UNC-6/NTR/C345C module;; Laminin EGF-like (Domains III and V)	Netrin-1 (Precursor) GN=NTN1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: netrin-1 [Orycteropus afer afer]
ENSG00000065325(GLP2R)	--	11.09106521	414	14.43573951	407	9.2403756	431	9.5678656	463	10.05009912	593	15.52898302	653	0.962022209	0.130092484	normal	0.341103223	0.519967505	normal	0.117143646	0.589411788	normal	0.055313346	0.428873999	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	K04582|0|hsa:9340|GLP2R; glucagon-like peptide 2 receptor; K04582 glucagon-like peptide 2 receptor (A)	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Glucagon-like peptide 2 receptor GN=GLP2R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: glucagon-like peptide 2 receptor [Tupaia chinensis]
ENSG00000065328(MCM10)	--	11.17821799	1079	11.099691	1057	13.8484479	1294	10.86374022	1048	11.47529	1091	7.723832287	733	0.97826981	-0.072783242	normal	0.979712932	0.024215066	normal	0.000208695	-0.826942235	normal	0.31371342	-0.277880998	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; 	"K10736|0|hsa:55388|MCM10, CNA43, DNA43; minichromosome maintenance complex component 10; K10736 minichromosome maintenance protein 10 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mcm10 replication factor;; Primase zinc finger	Protein MCM10 homolog GN=MCM10 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: protein MCM10 homolog [Ceratotherium simum simum]
ENSG00000065357(DGKA)	--	7.489250998	367	6.566080404	306	7.495082301	371	10.92402069	538	10.84275955	549	7.2053952	374	0.344764995	0.519188983	normal	0.001826254	0.818786259	normal	0.969233094	0.003314186	normal	0.092881987	0.462929897	normal	--	--	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|ptr:451976|DGKA; diacylglycerol kinase, alpha 80kDa; K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase accessory domain;; Diacylglycerol kinase N-terminus;; Diacylglycerol kinase catalytic domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; EF hand;; EF-hand domain	Diacylglycerol kinase alpha GN=DGKA OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: diacylglycerol kinase alpha isoform X3 [Tupaia chinensis] 
ENSG00000065361(ERBB3)	--	96.46683955	4261	97.07107893	3999	100.7070957	4283	114.3765963	4945	115.0963131	4879	77.42618718	3419	0.985902673	0.183884617	normal	0.969829144	0.265428644	normal	0.925364886	-0.333206723	normal	0.874611439	0.056263587	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);; Cellular Component: membrane (GO:0016020);; 	K05084|0|ptr:451980|ERBB3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; K05084 receptor tyrosine-protein kinase erbB-3 [EC:2.7.10.1] (A)	ErbB signaling pathway (ko04012);; Calcium signaling pathway (ko04020);; Endocytosis (ko04144);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Receptor L domain;; Growth factor receptor domain IV;; Furin-like cysteine rich region;; Protein kinase domain	Receptor tyrosine-protein kinase erbB-3 (Precursor) GN=ERBB3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: receptor tyrosine-protein kinase erbB-3 [Ceratotherium simum simum]
ENSG00000065413(ANKRD44)	--	1.845241557	105	1.69907989	127	7.554955858	133	1.175737903	112	1.158650143	84	0.90100745	75	0.969357073	0.06140708	normal	0.626848724	-0.608813682	normal	0.144985792	-0.82213749	normal	0.265176635	-0.451880519	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15503|0|hsa:91526|ANKRD44, PP6-ARS-B; ankyrin repeat domain 44; K15503 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B GN=ANKRD44 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B-like isoform 6 [Dasypus novemcinctus]
ENSG00000065427(KARS)	--	71.27142997	2921	70.26202664	2849	71.46239731	2904	77.78332677	3195	72.53109785	2910	69.73530845	2858	0.988282387	0.098471776	normal	0.989616654	0.009132177	normal	0.98972556	-0.031310543	normal	0.928141344	0.025752564	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K04567|0|ptr:454252|KARS; lysyl-tRNA synthetase; K04567 lysyl-tRNA synthetase, class II [EC:6.1.1.6] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class II (D, K and N);; OB-fold nucleic acid binding domain;; tRNA synthetases class II core domain (F)"	Lysine--tRNA ligase GN=KARS OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: lysine--tRNA ligase isoform 1 [Dasypus novemcinctus]
ENSG00000065457(ADAT1)	--	12.08252171	1191	16.134539	1224	13.12684316	1231	11.76185961	1143	14.04696375	1140	11.92722495	1241	0.978312192	-0.09006166	normal	0.975051695	-0.123837705	normal	0.982003788	0.00337678	normal	0.780487663	-0.070023435	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: adenosine deaminase activity (GO:0004000);; Biological Process: RNA processing (GO:0006396);; 	"K15440|0|hsa:23536|ADAT1, HADAT1; adenosine deaminase, tRNA-specific 1 (EC:3.5.4.34); K15440 tRNA-specific adenosine deaminase 1 [EC:3.5.4.34] (A)"	--	[A]	RNA processing and modification	Adenosine-deaminase (editase) domain	tRNA-specific adenosine deaminase 1 GN=ADAT1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: tRNA-specific adenosine deaminase 1 isoform X1 [Equus przewalskii]
ENSG00000065485(PDIA5)	--	14.39718	533	10.96891	409	10.72638	399	18.22419	675	15.17737	555	16.186707	598	0.882831421	0.309126377	normal	0.695257689	0.417630155	normal	0.161505383	0.573677487	normal	0.026779253	0.425089487	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K09583|0|hsa:10954|PDIA5, PDIR; protein disulfide isomerase family A, member 5 (EC:5.3.4.1); K09583 protein disulfide isomerase family A, member 5 [EC:5.3.4.1] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like;; Thioredoxin-like;; Redoxin;; AhpC/TSA family;; Thioredoxin-like domain;; Thioredoxin;; Thioredoxin domain;; Glutaredoxin	Protein disulfide-isomerase A5 (Precursor) GN=PDIA5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein disulfide-isomerase A5 [Pteropus alecto]
ENSG00000065491(TBC1D22B)	--	3.928246	254	4.321537	280	4.01676452	260	4.574213	296	4.179437599	269	4.4557	288	0.948963059	0.188877334	normal	0.963739023	-0.078812883	normal	0.958567708	0.138500032	normal	0.833883411	0.082027981	normal	[R]	General function prediction only	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	TBC1 domain family member 22B GN=TBC1D22B OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 22B isoform X3 [Mustela putorius furo] 
ENSG00000065518(NDUFB4)	--	120.4841136	975	123.7061204	990	117.6867928	940	128.6135529	1081	124.8093507	1007	112.8638237	920	0.974121896	0.117883669	normal	0.979064258	0.003131952	normal	0.978191567	-0.0392545	normal	0.923805752	0.028512552	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; 	"K03960|2.0084e-89|ptr:460612|NDUFB4; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa; K03960 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 4 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 GN=NDUFB4 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 [Ceratotherium simum simum]
ENSG00000065526(SPEN)	--	9.6544549	2723	10.605294	3011	11.335112	3122	9.417613014	2879	9.425160317	2979	8.828145	2602	0.989197622	0.049511373	normal	0.989661831	-0.036822549	normal	0.956410803	-0.270997016	normal	0.705827123	-0.087306073	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; SPOC domain"	Msx2-interacting protein GN=SPEN OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: msx2-interacting protein [Ceratotherium simum simum]
ENSG00000065534(MYLK)	--	17.2455358	3178	17.08325377	3048	18.17628121	3274	16.11858521	2792	14.30495482	2347	13.68668974	2354	0.974648449	-0.217540137	normal	0.801495862	-0.398245733	normal	0.456470609	-0.483966569	normal	0.019500364	-0.364050003	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K00907|0|hsa:4638|MYLK, AAT7, KRP, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, MYLK1, smMLCK; myosin light chain kinase (EC:2.7.11.18); K00907 myosin-light-chain kinase [EC:2.7.11.18] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971)	[Z]	Cytoskeleton	Immunoglobulin I-set domain;; Immunoglobulin domain;; Protein kinase domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Protein tyrosine kinase;; CD80-like C2-set immunoglobulin domain;; Fibronectin type III domain;; Alphaherpesvirus glycoprotein E;; Penicillin-Binding Protein C-terminus Family;; Natural killer cell receptor 2B4;; CD47 immunoglobulin-like domain	"Myosin light chain kinase, smooth muscle, deglutamylated form GN=MYLK OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: myosin light chain kinase, smooth muscle isoform X4 [Galeopterus variegatus]"
ENSG00000065548(ZC3H15)	--	36.19460397	1615	40.02070357	1802	37.906975	1682	29.08655723	1310	29.17780358	1294	27.30447	1220	0.878255747	-0.33244768	normal	0.367035267	-0.498691621	normal	0.461871359	-0.47108846	normal	0.003847461	-0.436571809	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger CCCH-type containing 15 [Equus caballus]
ENSG00000065559(MAP2K4)	--	20.860193	1359	21.87142	1418	20.85074164	1335	19.809933	1299	19.993438	1302	18.92768968	1236	0.979520651	-0.095865415	normal	0.974582336	-0.14439387	normal	0.977109249	-0.119311936	normal	0.577010037	-0.121262041	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04430|0|ptr:455065|MAP2K4; mitogen-activated protein kinase kinase 4; K04430 mitogen-activated protein kinase kinase 4 [EC:2.7.12.2] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Toll-like receptor signaling pathway (ko04620);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; GnRH signaling pathway (ko04912);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis B (ko05161);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Dual specificity mitogen-activated protein kinase kinase 4 GN=MAP2K4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual specificity mitogen-activated protein kinase kinase 4 isoform X1 [Orycteropus afer afer]
ENSG00000065600(TMEM206)	--	8.320099226	342	7.448762177	305	8.95733426	357	8.161553392	322	8.803330175	344	6.663081	262	0.961855942	-0.117225024	normal	0.95580503	0.151465297	normal	0.649933803	-0.452402491	normal	0.679827713	-0.135053861	normal	--	--	--	--	--	--	--	TMEM206 protein family	Transmembrane protein 206 GN=TMEM206 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 206 [Vicugna pacos]
ENSG00000065609(SNAP91)	--	0.789552736	54	0.866628302	47	0.933814597	59	0.41912428	23	0.466488064	25	0.740039497	46	0.196957705	-1.207948158	normal	0.751297633	-0.892170591	normal	0.959475806	-0.35698333	normal	0.1421731	-0.786120538	normal	--	--	Molecular Function: phospholipid binding (GO:0005543);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	ANTH domain;; ENTH domain	Clathrin coat assembly protein AP180 GN=SNAP91 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: clathrin coat assembly protein AP180 isoform X1 [Erinaceus europaeus] 
ENSG00000065613(SLK)	--	16.36802992	2436	17.18984568	2549	15.52617763	2268	18.19048188	2719	18.45985724	2740	16.919842	2522	0.984845438	0.127653523	normal	0.987388375	0.082770593	normal	0.98250867	0.144764617	normal	0.5827018	0.116427204	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08836|0|hsa:9748|SLK, LOSK, STK2, bA16H23.1, se20-9; STE20-like kinase (EC:2.7.11.1); K08836 STE20-like kinase [EC:2.7.11.1] (A)"	Oocyte meiosis (ko04114)	[T]	Signal transduction mechanisms	Polo kinase kinase;; Protein kinase domain;; Protein tyrosine kinase	STE20-like serine/threonine-protein kinase GN=SLK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: STE20-like serine/threonine-protein kinase isoform X1 [Physeter catodon]
ENSG00000065615(CYB5R4)	--	8.88907952	727	8.5375907	670	9.002823075	756	7.912871376	649	7.570400279	609	8.379005054	708	0.953652732	-0.194134596	normal	0.960797894	-0.15876936	normal	0.971308013	-0.10271595	normal	0.518057513	-0.151887212	normal	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[C]	Energy production and conversion	Cytochrome b5-like Heme/Steroid binding domain;; Oxidoreductase FAD-binding domain;; Oxidoreductase NAD-binding domain;; CS domain	Cytochrome b5 reductase 4 GN=CYB5R4 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: cytochrome b5 reductase 4-like isoform X1 [Pteropus alecto]
ENSG00000065618(COL17A1)	--	0.148964522	19	0.150677862	19	0.190329635	24	0.480004344	61	0.635486067	43	0.132001227	17	0.007211763	1.577209345	up	0.581287539	1.097442574	normal	0.98074125	-0.470416111	normal	0.318656591	0.940627707	normal	--	--	--	"K07603|0|hsa:1308|COL17A1, BA16H23.2, BP180, BPA-2, BPAG2, LAD-1; collagen, type XVII, alpha 1; K07603 collagen, type XVII, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	97 kDa linear IgA disease antigen GN=COL17A1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: collagen alpha-1(XVII) chain [Felis catus]
ENSG00000065621(GSTO2)	--	1.546071619	38	0.619547626	19	0.449229385	18	0.832113583	28	1.245135798	34	0.7559167	35	0.9681375	-0.450117894	normal	0.924703719	0.771649463	normal	0.878971225	0.896200702	normal	0.667173379	0.350017399	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K00799|4.26999e-180|pon:100448103|GSTO2; glutathione S-transferase omega 2; K00799 glutathione S-transferase [EC:2.5.1.18] (A)	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutaredoxin"	Glutathione S-transferase omega-2 GN=GSTO2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase omega-2 [Oryctolagus cuniculus] 
ENSG00000065665(SEC61A2)	--	12.74882303	385	11.28627276	345	13.04358	354	9.404192	296	9.876491135	302	12.866023	381	0.744166726	-0.408229396	normal	0.941071105	-0.21247801	normal	0.964725325	0.097349251	normal	0.57478948	-0.167459791	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: protein transport (GO:0015031);; Cellular Component: membrane (GO:0016020);; 	K10956|0|tup:102480124|SEC61A2; Sec61 alpha 2 subunit (S. cerevisiae); K10956 protein transport protein SEC61 subunit alpha (A)	Protein export (ko03060);; Protein processing in endoplasmic reticulum (ko04141);; Phagosome (ko04145)	[UO]	"Intracellular trafficking, secretion, and vesicular transport;; Posttranslational modification, protein turnover, chaperones"	SecY translocase;; Plug domain of Sec61p	Protein transport protein Sec61 subunit alpha isoform 2 GN=SEC61A2 OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec61 subunit alpha isoform 2 isoform 1 [Ceratotherium simum simum] 
ENSG00000065675(PRKCQ)	--	2.836291328	192	2.856257351	179	3.04935499	200	2.679079298	176	2.638663015	178	2.179444331	146	0.957588598	-0.155066497	normal	0.965672742	-0.029261	normal	0.761320889	-0.458250504	normal	0.581237946	-0.213095856	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	K18052|0|ggo:101127426|PRKCQ; protein kinase C theta type isoform 1; K18052 novel protein kinase C theta type [EC:2.7.11.13] (A)	NF-kappa B signaling pathway (ko04064);; Vascular smooth muscle contraction (ko04270);; Tight junction (ko04530);; T cell receptor signaling pathway (ko04660);; Inflammatory mediator regulation of TRP channels (ko04750);; Adipocytokine signaling pathway (ko04920);; Measles (ko05162)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Protein kinase C terminal domain	Protein kinase C theta type GN=PRKCQ OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein kinase C theta type isoform X1 [Mustela putorius furo] 
ENSG00000065717(TLE2)	--	3.060150919	135	2.533814804	118	3.20184252	107	1.32178736	58	2.56901908	112	1.543329227	50	0.000683186	-1.227701632	down	0.965855971	-0.095458747	normal	0.02127652	-1.082981849	normal	0.087653973	-0.731878703	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[B]	Chromatin structure and dynamics	"Groucho/TLE N-terminal Q-rich domain;; WD domain, G-beta repeat"	Transducin-like enhancer protein 2 GN=TLE2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transducin-like enhancer protein 2 isoform X1 [Pteropus alecto]
ENSG00000065802(ASB1)	--	15.02445973	1310	12.11815342	1254	14.61453348	1322	8.334319	824	9.381485	974	9.931340404	907	0.006389529	-0.698639576	normal	0.772681734	-0.385441243	normal	0.156372346	-0.551073461	normal	0.000282237	-0.543436421	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10323|0|ptr:460059|ASB1; ankyrin repeat and SOCS box containing 1; K10323 ankyrin repeat and SOCS box protein 1 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 1 GN=ASB1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 1 [Mustela putorius furo] 
ENSG00000065809(FAM107B)	--	73.6613561	3917	72.75639149	3961	67.06368212	3579	54.33916273	2785	48.35248056	2501	52.77084357	2695	0.291498466	-0.522659606	normal	0.01006136	-0.684454251	normal	0.749653865	-0.417358776	normal	0.000165535	-0.543091662	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1151)	Protein FAM107B GN=FAM107B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: reticulocyte-binding protein 2 homolog a isoform X1 [Tupaia chinensis]
ENSG00000065833(ME1)	--	43.43743	2311	50.80651	2680	48.15769	2505	34.35212	1840	34.74735	1842	35.68499	1894	0.855242783	-0.359375307	normal	0.150737059	-0.562001559	normal	0.733564799	-0.411379131	normal	0.00246874	-0.448017076	normal	[C]	Energy production and conversion	Molecular Function: malate dehydrogenase (decarboxylating) (NAD+) activity (GO:0004471);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00029|0|hsa:4199|ME1, HUMNDME, MES; malic enzyme 1, NADP(+)-dependent, cytosolic (EC:1.1.1.40); K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] (A)"	Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; PPAR signaling pathway (ko03320)	[C]	Energy production and conversion	"Malic enzyme, NAD binding domain;; Malic enzyme, N-terminal domain"	NADP-dependent malic enzyme GN=ME1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADP-dependent malic enzyme [Oryctolagus cuniculus]
ENSG00000065882(TBC1D1)	--	18.18096856	1149	17.97648717	1101	18.03358973	1121	17.81755504	1062	19.47576501	1187	16.0142575	1064	0.97182592	-0.144226614	normal	0.977857136	0.086963852	normal	0.978007448	-0.08346398	normal	0.868332882	-0.046158981	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K18341|0|pps:100994615|TBC1D1; TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1; K18341 TBC1 domain family member 1 (A)"	AMPK signaling pathway (ko04152)	[R]	General function prediction only	Rab-GTPase-TBC domain;; Domain of unknown function (DUF3350);; Phosphotyrosine interaction domain (PTB/PID)	TBC1 domain family member 1 GN=TBC1D1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: TBC1 domain family member 1 isoform X1 [Equus caballus]
ENSG00000065883(CDK13)	--	8.767802065	1126	9.414065995	1198	9.550840649	1129	10.36823507	1334	12.10559634	1554	12.72286371	1572	0.958192907	0.213451751	normal	0.848286227	0.353539218	normal	0.469810548	0.468729859	normal	0.030641247	0.348467246	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08819|0|hsa:8621|CDK13, CDC2L, CDC2L5, CHED, hCDK13; cyclin-dependent kinase 13 (EC:2.7.11.23 2.7.11.22); K08819 cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 13 GN=CDK13 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: cyclin-dependent kinase 13 [Equus caballus]
ENSG00000065911(MTHFD2)	--	87.55412	4284	92.874184	4505	87.824836	4050	44.374137	2032	38.932722	1876	84.548786	3914	2.45E-09	-1.106300035	down	1.77E-12	-1.284603307	down	0.99156916	-0.057547734	normal	0.045746881	-0.734268124	normal	[H]	Coenzyme transport and metabolism	Molecular Function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13403|0|hsa:10797|MTHFD2, NMDMC; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase (EC:3.5.4.9 1.5.1.15); K13403 methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9] (A)"	One carbon pool by folate (ko00670)	[H]	Coenzyme transport and metabolism	"Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain;; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain"	Methenyltetrahydrofolate cyclohydrolase (Precursor) GN=MTHFD2 OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	"PREDICTED: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Ailuropoda melanoleuca]"
ENSG00000065923(SLC9A7)	--	6.046181347	1002	5.107302611	863	5.94699657	1015	10.71451357	1844	8.343604328	1426	6.573117693	1125	7.63E-05	0.848151366	normal	0.00721619	0.70214832	normal	0.972038721	0.139955686	normal	0.074461772	0.5872737	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12041|0|hsa:84679|SLC9A7, NHE-7, NHE7, SLC9A6; solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7; K12041 solute carrier family 9 (sodium/hydrogen exchanger), member 6/7 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 7 GN=SLC9A7 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 7 [Condylura cristata]
ENSG00000065970(FOXJ2)	--	6.5696066	723	6.544247	722	6.140920429	679	5.6856471	622	6.082211	664	5.99841	663	0.931832897	-0.24734595	normal	0.96492027	-0.141932036	normal	0.974241919	-0.042598129	normal	0.543659221	-0.145134611	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09403|0|hsa:55810|FOXJ2, FHX; forkhead box J2; K09403 forkhead box protein J2/3 (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein J2 GN=FOXJ2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein J2 [Pteropus alecto]
ENSG00000065978(YBX1)	--	359.6931644	11183	374.7980038	11905	386.0355619	12289	445.66503	13980	408.625592	12750	454.811309	14315	0.981503891	0.291188992	normal	0.99628774	0.077493556	normal	0.992305206	0.211844529	normal	0.362737823	0.1933344	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09276|2.14101e-87|pps:100967524|YBX1; Y box binding protein 1; K09276 Y-box-binding protein 1 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	'Cold-shock' DNA-binding domain	Nuclease-sensitive element-binding protein 1 GN=YBX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nuclease-sensitive element-binding protein 1 [Galeopterus variegatus]
ENSG00000065989(PDE4A)	--	2.513057628	240	2.25926997	201	2.093584424	202	1.342770078	126	1.826800638	164	1.4603597	116	0.001960268	-0.951879625	normal	0.908401681	-0.312319789	normal	0.04800377	-0.800511564	normal	0.014970475	-0.684707496	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13293|0|hsa:5141|PDE4A, DPDE2, PDE4, PDE46; phosphodiesterase 4A, cAMP-specific (EC:3.1.4.53); K13293 cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; cAMP signaling pathway (ko04024);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase	"cAMP-specific 3',5'-cyclic phosphodiesterase 4A GN=PDE4A OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4A isoformX2 [Canis lupus familiaris]"
ENSG00000066027(PPP2R5A)	--	13.54662606	695	15.33750502	785	15.87558634	806	13.307893	678	12.94613549	659	13.03141525	666	0.973271441	-0.066411314	normal	0.917700621	-0.273265334	normal	0.910219627	-0.282964104	normal	0.313525305	-0.211781939	normal	--	--	Cellular Component: protein phosphatase type 2A complex (GO:0000159);; Biological Process: signal transduction (GO:0007165);; Molecular Function: protein phosphatase regulator activity (GO:0019888);; 	K11584|0|aml:100480070|serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform-like; K11584 serine/threonine-protein phosphatase 2A regulatory subunit B' (A)	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Dopaminergic synapse (ko04728)	[T]	Signal transduction mechanisms	Protein phosphatase 2A regulatory B subunit (B56 family)	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform GN=PPP2R5A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform isoform X1 [Tupaia chinensis]
ENSG00000066032(CTNNA2)	--	0.077156977	4	0	0	0	0	0.539101407	8	0.113319397	6	0.286377529	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell adhesion (GO:0007155);; Molecular Function: actin filament binding (GO:0051015);; 	"K05691|0|ocu:100352391|CTNNA2; catenin (cadherin-associated protein), alpha 2; K05691 catenin alpha (A)"	Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Bacterial invasion of epithelial cells (ko05100);; Pathways in cancer (ko05200);; Endometrial cancer (ko05213);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[W]	Extracellular structures	Vinculin family	Catenin alpha-2 GN=CTNNA2 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: catenin alpha-2 isoform X2 [Oryctolagus cuniculus]
ENSG00000066044(ELAVL1)	--	44.17408472	1789	43.15163094	1720	50.85414715	2025	48.1199802	1941	46.56442966	1844	44.11163643	1748	0.984039068	0.086742938	normal	0.983605606	0.078936497	normal	0.965141256	-0.22033089	normal	0.945420517	-0.021494902	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13088|0|pps:100976065|ELAVL1; ELAV like RNA binding protein 1; K13088 ELAV-like protein 1 (A)	AMPK signaling pathway (ko04152)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	ELAV-like protein 1 GN=ELAVL1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ELAV-like protein 1 isoform 1 [Canis lupus familiaris] 
ENSG00000066056(TIE1)	--	0	0	0	0	0	0	0	0	0	0	0.012507034	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05120|0|ptr:469308|TIE1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1; K05120 tyrosine kinase receptor 1 [EC:2.7.10.1] (A)	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Human growth factor-like EGF	Tyrosine-protein kinase receptor Tie-1 (Precursor) GN=TIE1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase receptor Tie-1 [Camelus dromedarius]
ENSG00000066084(DIP2B)	--	10.66766301	1633	11.97199329	1835	12.0471742	1830	12.36376602	1891	12.669747	1925	12.03928946	1838	0.973113653	0.180634276	normal	0.985326648	0.047613512	normal	0.986078319	-0.001996678	normal	0.762719635	0.072642797	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	AMP-binding enzyme;; DMAP1-binding Domain	Disco-interacting protein 2 homolog B GN=DIP2B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: disco-interacting protein 2 homolog B isoform 1 [Odobenus rosmarus divergens]
ENSG00000066117(SMARCD1)	--	22.01962202	1221	23.12605617	1221	18.61344895	1081	26.183669	1441	36.288666	1759	25.4700087	1375	0.961502276	0.207933818	normal	0.340983833	0.504742227	normal	0.862734417	0.338352991	normal	0.045338194	0.355551677	normal	[B]	Chromatin structure and dynamics	Molecular Function: protein binding (GO:0005515);; 	"K11650|0|ssc:100155712|SMARCD1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1; K11650 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	SWIB/MDM2 domain	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 isoform X1 [Elephantulus edwardii]
ENSG00000066135(KDM4A)	--	8.615193001	795	8.606458	804	9.449795326	886	9.271416117	872	9.992261637	925	13.03238392	1226	0.972899244	0.102352104	normal	0.960672719	0.180514554	normal	0.503887369	0.459619196	normal	0.354064189	0.262746999	normal	--	--	--	"K06709|0|pon:100172003|KDM4A, JHDM3A, JMJD2A; lysine (K)-specific demethylase 4A (EC:1.14.11.-); K06709 jumonji domain-containing protein 2 [EC:1.14.11.-] (A)"	--	[L]	"Replication, recombination and repair"	"JmjC domain, hydroxylase;; PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; jmjN domain;; PHD-finger;; PHD-finger"	Lysine-specific demethylase 4A GN=KDM4A OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: lysine-specific demethylase 4A [Felis catus] 
ENSG00000066136(NFYC)	--	18.45238481	658	23.78278354	806	20.14958269	726	14.4179261	492	15.63066557	538	17.68172351	633	0.56853497	-0.449044093	normal	0.085637869	-0.603204858	normal	0.95007195	-0.205596456	normal	0.020410216	-0.417629522	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K08066|0|mcf:101865828|uncharacterized LOC101865828; K08066 nuclear transcription factor Y, gamma (A)"	Antigen processing and presentation (ko04612);; Tuberculosis (ko05152)	[K]	Transcription	Histone-like transcription factor (CBF/NF-Y) and archaeal histone;; Core histone H2A/H2B/H3/H4	Nuclear transcription factor Y subunit gamma GN=NFYC OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nuclear transcription factor Y subunit gamma [Galeopterus variegatus]
ENSG00000066185(ZMYND12)	--	0.270185	8	0.135142	4	0.13244	3	0.232564	7	0.22863	6	0.164987	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Tetratricopeptide repeat;; MYND finger;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Zinc finger MYND domain-containing protein 12 GN=ZMYND12 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger MYND domain-containing protein 12 [Galeopterus variegatus]
ENSG00000066230(SLC9A3)	--	0	0	0.0843794	4	0.0396236	1	0.0411124	2	0.0399729	1	0.183847	9	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12040|0|hsa:6550|SLC9A3, NHE3; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3; K12040 solute carrier family 9 (sodium/hydrogen exchanger), member 3 (A)"	Proximal tubule bicarbonate reclamation (ko04964);; Protein digestion and absorption (ko04974);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 3 GN=SLC9A3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 3 [Mustela putorius furo]
ENSG00000066248(NGEF)	--	8.680466304	441	4.708505	232	9.17411028	371	9.437708542	421	9.574160523	411	5.006831346	255	0.965845757	-0.097443169	normal	0.005966483	0.799620718	normal	0.339870834	-0.546510247	normal	0.967999994	0.036048985	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K07525|0|ptr:460020|NGEF; neuronal guanine nucleotide exchange factor; K07525 neuronal guanine nucleotide exchange factor (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	RhoGEF domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Ephexin-1 GN=NGEF OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_006379 [Ailuropoda melanoleuca]
ENSG00000066279(ASPM)	--	18.05816	3118	18.41008	3172	18.49097	3040	18.6482549	3357	16.756999	3039	19.949011	3641	0.989641904	0.0756834	normal	0.988775999	-0.083182133	normal	0.967633161	0.251857347	normal	0.719802572	0.084321431	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16743|0|ptr:449566|ASPM; asp (abnormal spindle) homolog, microcephaly associated (Drosophila); K16743 abnormal spindle-like microcephaly-associated protein (A)"	--	[Z]	Cytoskeleton	IQ calmodulin-binding motif;; CAMSAP CH domain;; Calponin homology (CH) domain	Abnormal spindle-like microcephaly-associated protein GN=ASPM OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: abnormal spindle-like microcephaly-associated protein [Galeopterus variegatus]
ENSG00000066294(CD84)	--	0.006891855	1	0	0	0	0	0	0	0	0	0.006844319	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06511|0|hsa:8832|CD84, LY9B, SLAMF5, hCD84, mCD84; CD84 molecule; K06511 CD84 antigen (A)"	--	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	SLAM family member 5 (Precursor) GN=CD84 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SLAM family member 5 isoform X1 [Galeopterus variegatus]
ENSG00000066322(ELOVL1)	--	85.26421	1801	79.45225	1684	79.94388	1688	115.77058	2467	96.5792	2023	97.86717	2066	0.691620325	0.42281798	normal	0.957294019	0.242978311	normal	0.93678193	0.283004362	normal	0.045079266	0.319971508	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K10247|0|hsa:64834|ELOVL1, Ssc1; ELOVL fatty acid elongase 1 (EC:2.3.1.199); K10247 elongation of very long chain fatty acids protein 1 [EC:2.3.1.199] (A)"	Fatty acid elongation (ko00062)	[I]	Lipid transport and metabolism	GNS1/SUR4 family	Elongation of very long chain fatty acids protein 1 GN=ELOVL1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: elongation of very long chain fatty acids protein 1 isoform X1 [Condylura cristata]
ENSG00000066336(SPI1)	--	0.305154478	3	0.149624571	3	0.19317245	3	0.097336514	2	0.079967383	1	0.047058111	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09438|3.02027e-171|hsa:6688|SPI1, OF, PU.1, SFPI1, SPI-1, SPI-A; Spi-1 proto-oncogene; K09438 transcription factor PU.1 (A)"	Osteoclast differentiation (ko04380);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Acute myeloid leukemia (ko05221)	[K]	Transcription	Ets-domain	Transcription factor PU.1 GN=SPI1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor PU.1 [Camelus dromedarius]
ENSG00000066379(ZNRD1)	--	12.696644	123	14.08648183	140	13.62085362	136	16.551202	168	16.66326698	161	13.604237	136	0.851700817	0.414524973	normal	0.954895371	0.178409096	normal	0.968365448	-0.008200257	normal	0.65024283	0.199089079	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase activity (GO:0003916);; Cellular Component: chromosome (GO:0005694);; Biological Process: DNA topological change (GO:0006265);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: zinc ion binding (GO:0008270);; "	K03000|3.17437e-89|ptr:471952|ZNRD1; zinc ribbon domain containing 1 (EC:2.7.7.6); K03000 DNA-directed RNA polymerase I subunit RPA12 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020)	[K]	Transcription	Transcription factor S-II (TFIIS)	DNA-directed RNA polymerase I subunit RPA12 GN=ZNRD1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase I subunit RPA12 isoform 1 [Ceratotherium simum simum]
ENSG00000066382(MPPED2)	--	0.028894754	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[R]	General function prediction only	Calcineurin-like phosphoesterase	Metallophosphoesterase MPPED2 GN=MPPED2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: metallophosphoesterase MPPED2 isoform 1 [Equus caballus] 
ENSG00000066405(CLDN18)	--	0.017142681	1	0.112949931	7	0.051077644	2	0.034120913	2	0.157004574	9	0.064149471	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|0|ptr:470935|CLDN18; claudin 18; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-18 GN=CLDN18 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: claudin-18 isoform X1 [Equus przewalskii]
ENSG00000066422(ZBTB11)	--	8.81357	865	9.660929	965	10.906597	1081	8.20646	802	8.950962	894	9.89156	983	0.968335785	-0.139672416	normal	0.970675828	-0.131466549	normal	0.970744969	-0.145181566	normal	0.523533016	-0.140100251	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10498|0|hsa:27107|ZBTB11, ZNF-U69274, ZNF913; zinc finger and BTB domain containing 11; K10498 zinc finger and BTB domain-containing protein 11 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; BTB/POZ domain;; Zinc-finger double-stranded RNA-binding;; Drought induced 19 protein (Di19), zinc-binding;; C2H2 type zinc-finger (2 copies)"	Zinc finger and BTB domain-containing protein 11 GN=ZBTB11 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 11 [Odobenus rosmarus divergens]
ENSG00000066427(ATXN3)	--	19.0176499	1606	23.12842431	1941	24.71664741	1829	19.80627365	1832	19.32017173	1702	18.55900926	1887	0.976283105	0.158972882	normal	0.967039883	-0.210820077	normal	0.985835045	0.036718015	normal	0.980122653	-0.00909289	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Biological Process: protein deubiquitination (GO:0016579);; 	K11863|0|ptr:738729|ATXN3; ataxin 3; K11863 Ataxin-3 [EC:3.4.22.-] (A)	Protein processing in endoplasmic reticulum (ko04141)	[R]	General function prediction only	Josephin;; Ubiquitin interaction motif	Ataxin-3 GN=ATXN3 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	ataxin 3 [Equus caballus] 
ENSG00000066455(GOLGA5)	--	15.82930411	1006	12.35264288	779	12.924256	811	15.30137397	959	17.058203	1076	15.46462811	987	0.975324495	-0.09970386	normal	0.585126771	0.443820306	normal	0.920813018	0.274591884	normal	0.320407317	0.198051035	normal	--	--	Biological Process: Golgi organization (GO:0007030);; 	--	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Golgin subfamily A member 5	Golgin subfamily A member 5 GN=GOLGA5 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: golgin subfamily A member 5 [Vicugna pacos]
ENSG00000066468(FGFR2)	--	0.077822056	4	0.073904043	4	0.07637797	3	0.07165147	6	0.100988191	5	0.096627447	5	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05093|0|pps:100981139|FGFR2; fibroblast growth factor receptor 2; K05093 fibroblast growth factor receptor 2 [EC:2.7.10.1] (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Prostate cancer (ko05215);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Fibroblast growth factor receptor 2 (Precursor) GN=FGFR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor receptor 2 isoform X1 [Tupaia chinensis]
ENSG00000066557(LRRC40)	--	9.56361	407	9.61486	406	10.4477	434	10.5205	455	10.4076	444	9.50022	406	0.961953779	0.129542831	normal	0.963933554	0.107271225	normal	0.965060735	-0.104131524	normal	0.903207025	0.044193904	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 40 GN=LRRC40 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 40 [Equus przewalskii]
ENSG00000066583(ISOC1)	--	16.60159	454	14.933138	411	14.53888	396	12.153918	336	13.023247	354	12.505938	341	0.569335197	-0.463233256	normal	0.932408008	-0.235879379	normal	0.938332234	-0.223101076	normal	0.187804379	-0.311775536	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	Isochorismatase family	Isochorismatase domain-containing protein 1 GN=ISOC1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	isochorismatase domain-containing protein 1 [Bos taurus] 
ENSG00000066629(EML1)	--	11.80877625	941	14.13918753	954	14.61232643	970	16.29487113	1359	21.184367	1554	11.89200344	988	0.336508646	0.498765553	normal	0.011379582	0.681644272	normal	0.979249843	0.018206727	normal	0.146029238	0.423437273	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K18595|0|hsa:2009|EML1, ELP79, EMAP, EMAPL, HuEMAP; echinoderm microtubule associated protein like 1; K18595 echinoderm microtubule-associated protein-like 1/2 (A)"	--	[S]	Function unknown	"HELP motif;; WD domain, G-beta repeat"	Echinoderm microtubule-associated protein-like 1 GN=EML1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: echinoderm microtubule-associated protein-like 1 isoform 1 [Orcinus orca]
ENSG00000066651(TRMT11)	--	9.687689817	298	11.44289331	339	9.502618863	279	7.929899798	251	8.636933552	265	9.301058486	287	0.915712093	-0.276899309	normal	0.818743065	-0.374822996	normal	0.967176551	0.032321434	normal	0.486172081	-0.210988395	normal	[L]	"Replication, recombination and repair"	--	K15430|0|pps:100987629|TRMT11; tRNA methyltransferase 11 homolog (S. cerevisiae); K15430 tRNA (guanine10-N2)-methyltransferase [EC:2.1.1.214] (A)	--	[L]	"Replication, recombination and repair"	Putative RNA methylase family UPF0020;; Methyltransferase domain;; DNA methylase	tRNA (guanine(10)-N2)-methyltransferase homolog GN=TRMT11 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (guanine(10)-N2)-methyltransferase homolog [Odobenus rosmarus divergens]
ENSG00000066654(THUMPD1)	--	13.88002	1095	16.56110845	1265	13.53439	1039	16.74661674	1284	16.26524	1271	14.35234044	1113	0.961937871	0.198624503	normal	0.981755779	-0.014582521	normal	0.977290269	0.090838729	normal	0.711202845	0.088046641	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K06963|0|hsa:55623|THUMPD1; THUMP domain containing 1; K06963 tRNA acetyltransferase TAN1 (A)	--	[R]	General function prediction only	THUMP domain	THUMP domain-containing protein 1 GN=THUMPD1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: THUMP domain-containing protein 1 [Physeter catodon]
ENSG00000066697(MSANTD3)	--	28.2977562	922	33.55788413	1123	28.258554	909	38.44405981	1277	34.373576	1116	35.90564652	1149	0.589488866	0.43846438	normal	0.980082442	-0.030406384	normal	0.869333365	0.329246892	normal	0.185879883	0.240088513	normal	--	--	--	--	--	--	--	Myb/SANT-like DNA-binding domain	Myb/SANT-like DNA-binding domain-containing protein 3 GN=MSANTD3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: myb/SANT-like DNA-binding domain-containing protein 3-like isoform X1 [Pantholops hodgsonii] 
ENSG00000066735(KIF26A)	--	1.712070106	226	1.498210146	204	2.001661145	276	1.43833361	196	1.201524021	157	1.002184754	133	0.938792072	-0.234587021	normal	0.841666789	-0.395875487	normal	0.000137197	-1.05303592	down	0.042184582	-0.560624668	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10404|0|hsa:26153|KIF26A; kinesin family member 26A; K10404 kinesin family member 26 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF26A GN=KIF26A OS=Homo sapiens (Human) PE=2 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF26A [Galeopterus variegatus]
ENSG00000066739(ATG2B)	--	3.8488913	922	3.68805916	876	4.069091661	957	4.382919604	1051	4.432073551	1060	4.943952975	1186	0.967823222	0.157845269	normal	0.93635318	0.253237006	normal	0.903593131	0.300793988	normal	0.199160767	0.238389349	normal	--	--	--	"K17906|0|hsa:55102|ATG2B, C14orf103; autophagy related 2B; K17906 autophagy-related protein 2 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"ATG C terminal domain;; N-terminal region of Chorein, a TM vesicle-mediated sorter;; Autophagy-related protein 2 CAD motif"	Autophagy-related protein 2 homolog B GN=ATG2B OS=Homo sapiens (Human) PE=1 SV=5	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: autophagy-related protein 2 homolog B [Ceratotherium simum simum]
ENSG00000066777(ARFGEF1)	--	10.86127126	1487	11.67826199	1644	11.29500264	1557	12.18830117	1737	11.35218999	1607	12.5544345	1719	0.968994716	0.193176034	normal	0.983626486	-0.054216482	normal	0.978757721	0.134384891	normal	0.696304458	0.08973625	normal	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K18442|0|hsa:10565|ARFGEF1, ARFGEP1, BIG1, P200; ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited); K18442 brefeldin A-inhibited guanine nucleotide-exchange protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; Guanine nucleotide exchange factor in Golgi transport N-terminal;; Domain of unknown function (DUF1981)	Brefeldin A-inhibited guanine nucleotide-exchange protein 1 GN=ARFGEF1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: brefeldin A-inhibited guanine nucleotide-exchange protein 1 [Ceratotherium simum simum]
ENSG00000066827(ZFAT)	--	1.53149297	164	1.758215182	183	2.109822994	185	1.835328716	173	2.106681238	224	2.814735719	276	0.966698504	0.045825949	normal	0.925979839	0.268222236	normal	0.384366201	0.565045734	normal	0.359972933	0.31949038	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc-finger domain;; Drought induced 19 protein (Di19), zinc-binding"	Zinc finger protein ZFAT GN=ZFAT OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein ZFAT isoform X1 [Equus przewalskii]
ENSG00000066855(MTFR1)	--	22.15766838	995	20.98397615	903	23.75077212	1033	23.59595521	1039	21.84107116	966	23.98463992	1082	0.979373234	0.031547289	normal	0.976013238	0.075747981	normal	0.978992053	0.058485138	normal	0.844886194	0.053883562	normal	--	--	--	--	--	--	--	Mitochondrial fission regulator	Mitochondrial fission regulator 1 (Precursor) GN=MTFR1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mitochondrial fission regulator 1 [Ceratotherium simum simum]
ENSG00000066923(STAG3)	--	1.165501291	21	0.955145	15	1.928313538	32	0.616409581	13	0.946755	14	0.632400247	13	0.977089228	-0.660736649	normal	--	--	--	0.696740175	-1.215087562	normal	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	K13055|0|hsa:10734|STAG3; stromal antigen 3; K13055 cohesin complex subunit SA-3 (A)	Oocyte meiosis (ko04114)	[D]	"Cell cycle control, cell division, chromosome partitioning"	STAG domain	Cohesin subunit SA-3 GN=STAG3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cohesin subunit SA-3 isoform X1 [Tupaia chinensis]
ENSG00000066926(FECH)	--	21.977193	1019	21.211165	1062	16.81952326	865	20.75783956	979	22.63257201	979	20.155606	944	0.976452503	-0.088469442	normal	0.971080692	-0.138623887	normal	0.972504664	0.117598423	normal	0.883261986	-0.043325021	normal	[H]	Coenzyme transport and metabolism	Molecular Function: ferrochelatase activity (GO:0004325);; Biological Process: heme biosynthetic process (GO:0006783);; 	K01772|0|mcc:695759|FECH; ferrochelatase; K01772 ferrochelatase [EC:4.99.1.1] (A)	Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	Ferrochelatase	"Ferrochelatase, mitochondrial (Precursor) GN=FECH OS=Homo sapiens (Human) PE=1 SV=2"	H	Coenzyme transport and metabolism	"PREDICTED: ferrochelatase, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000066933(MYO9A)	--	8.606369	1624	11.49001908	1747	8.901858493	1736	7.124827965	1417	7.2170269	1197	7.788185368	1571	0.958131519	-0.227313676	normal	0.131641236	-0.566287008	normal	0.976723325	-0.152235737	normal	0.058851593	-0.308163748	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: signal transduction (GO:0007165);; Cellular Component: myosin complex (GO:0016459);; 	K10360|0|hsa:4649|MYO9A; myosin IXA; K10360 myosin IX (A)	--	[N]	Cell motility	Myosin head (motor domain);; RhoGAP domain;; Ras association (RalGDS/AF-6) domain;; IQ calmodulin-binding motif	Unconventional myosin-IXa GN=MYO9A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-IXa [Galeopterus variegatus]
ENSG00000067048(DDX3Y)	--	29.57956943	2222	32.97776426	2499	31.79676568	2356	11.67454346	879	11.9551444	859	11.11014065	835	5.02E-14	-1.367196106	down	0	-1.560357245	down	0	-1.50308794	down	6.28E-29	-1.481054692	down	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K17642|0|hsa:8653|DDX3Y, DBY; DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked (EC:3.6.4.13); K17642 ATP-dependent RNA helicase DDX3Y [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	ATP-dependent RNA helicase DDX3Y GN=DDX3Y OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ATP-dependent RNA helicase DDX3Y-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000067057(PFKP)	--	262.3818236	14204	240.7296361	12948	272.5175871	14861	216.4569716	11792	167.4571343	9029	143.1266265	7625	0.980105351	-0.299285506	normal	0.401856673	-0.541441539	normal	7.95E-07	-0.970872853	normal	0.00234586	-0.584990652	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: 6-phosphofructokinase activity (GO:0003872);; Biological Process: glycolytic process (GO:0006096);; 	"K00850|0|pps:100980605|PFKP; phosphofructokinase, platelet; K00850 6-phosphofructokinase 1 [EC:2.7.1.11] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; RNA degradation (ko03018);; AMPK signaling pathway (ko04152);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Phosphofructokinase	"ATP-dependent 6-phosphofructokinase, platelet type {ECO:0000255|HAMAP-Rule:MF_03184} GN=PFKP OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	PREDICTED: 6-phosphofructokinase type C-like [Ochotona princeps]
ENSG00000067064(IDI1)	--	69.332645	2191	89.13904	2759	89.366942	2779	32.042817	1038	34.085332	1060	76.381212	2420	5.09E-09	-1.107459136	down	1.58E-14	-1.400220376	down	0.974360058	-0.207728987	normal	0.096893256	-0.793036615	normal	[I]	Lipid transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K01823|0|hsa:3422|IDI1, IPP1, IPPI1; isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2); K01823 isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2] (A)"	Terpenoid backbone biosynthesis (ko00900)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	NUDIX domain	Isopentenyl-diphosphate Delta-isomerase 1 GN=IDI1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: isopentenyl-diphosphate Delta-isomerase 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000067066(SP100)	--	11.1943965	649	13.03239864	734	11.68837234	683	11.38426783	622	10.89272915	605	10.31739715	643	0.970469801	-0.091913862	normal	0.895101011	-0.299590387	normal	0.970802554	-0.095141131	normal	0.481361855	-0.164953566	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	"K15413|0|hsa:6672|SP100, lysp100b; SP100 nuclear antigen; K15413 nuclear autoantigen Sp-100 (A)"	Herpes simplex infection (ko05168);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sp100 domain;; SAND domain;; Bromodomain	Nuclear autoantigen Sp-100 GN=SP100 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: SP100 nuclear antigen [Ceratotherium simum simum]
ENSG00000067082(KLF6)	--	16.86430168	1248	21.02287214	1581	19.3286947	1437	24.3427248	1827	18.11143883	1333	25.96486094	1946	0.260838489	0.518496034	normal	0.939454302	-0.267308292	normal	0.650469681	0.428771022	normal	0.451417836	0.238155949	normal	[R]	General function prediction only	--	K09207|6.02378e-159|ptr:450269|KLF6; Kruppel-like factor 6; K09207 krueppel-like factor 6/7 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 6 GN=KLF6 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: Krueppel-like factor 6-like [Tupaia chinensis] 
ENSG00000067113(PLPP1)	--	24.94493	566	21.55441	495	20.30299	464	20.35042	469	22.68569	514	22.71731	519	0.890180583	-0.301146743	normal	0.970667019	0.032814894	normal	0.959464632	0.152847042	normal	0.900709545	-0.042988795	normal	[I]	Lipid transport and metabolism	--	K01080|0|ptr:461869|PPAP2A; phosphatidic acid phosphatase type 2A; K01080 phosphatidate phosphatase [EC:3.1.3.4] (A)	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Sphingolipid metabolism (ko00600);; Fc gamma R-mediated phagocytosis (ko04666);; Fat digestion and absorption (ko04975);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	PAP2 superfamily	Lipid phosphate phosphohydrolase 1 GN=PPAP2A OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: lipid phosphate phosphohydrolase 1 isoformX3 [Sus scrofa]
ENSG00000067141(NEO1)	--	24.959464	3349	23.45575252	3144	22.73012935	2933	18.68473757	2482	21.58275454	2785	22.65318	3002	0.559999456	-0.462811834	normal	0.9785136	-0.196250076	normal	0.990018015	0.025242599	normal	0.242250027	-0.209698149	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: integral component of membrane (GO:0016021);; 	K06766|0|cjc:100385847|NEO1; neogenin 1; K06766 neogenin (A)	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	"Neogenin C-terminus;; Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Interferon-alpha/beta receptor, fibronectin type III;; CD80-like C2-set immunoglobulin domain;; Tissue factor;; Alphaherpesvirus glycoprotein E"	Neogenin (Precursor) GN=NEO1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neogenin-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000067167(TRAM1)	--	146.4275865	5443	186.737919	6886	169.17012	6135	602.01846	22627	618.73479	23091	592.84788	22169	0	2.024435278	up	0	1.723946739	up	0	1.844861137	up	1.44E-35	1.857131247	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K14010|0|hsa:23471|TRAM1, PNAS8, TRAM, TRAMP; translocation associated membrane protein 1; K14010 translocating chain-associated membrane protein 1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TRAM1-like protein;; TLC domain	Translocating chain-associated membrane protein 1 GN=TRAM1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: translocating chain-associated membrane protein 1 isoform X1 [Equus caballus]
ENSG00000067177(PHKA1)	--	16.91554631	1559	13.94286452	1392	15.14337732	1434	15.48041637	1513	15.77289486	1520	15.02252832	1427	0.982567262	-0.073967202	normal	0.979560994	0.105375978	normal	0.983510419	-0.01533492	normal	0.995568656	0.003095443	normal	--	--	--	"K07190|0|hsa:5255|PHKA1, PHKA; phosphorylase kinase, alpha 1 (muscle) (EC:2.7.11.19); K07190 phosphorylase kinase alpha/beta subunit (A)"	Calcium signaling pathway (ko04020);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 15	"Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform GN=PHKA1 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform isoform X1 [Felis catus]"
ENSG00000067182(TNFRSF1A)	--	225.2643178	8329	199.8020276	7386	213.4673284	7993	201.5936518	7488	216.9716954	8020	170.6164756	6366	0.990755847	-0.18435923	normal	0.994154304	0.097363282	normal	0.948796542	-0.336569858	normal	0.53719273	-0.137681372	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K03158|0|hsa:7132|TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60; tumor necrosis factor receptor superfamily, member 1A; K03158 tumor necrosis factor receptor superfamily member 1A (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Sphingolipid signaling pathway (ko04071);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; TNF signaling pathway (ko04668);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168)	--	--	TNFR/NGFR cysteine-rich region;; Death domain	Tumor necrosis factor-binding protein 1 (Precursor) GN=TNFRSF1A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 1A [Ceratotherium simum simum]
ENSG00000067191(CACNB1)	--	4.545555475	343	3.203883776	245	3.239795901	243	2.315035828	164	3.163067409	231	2.961570936	216	1.60E-05	-1.088127999	down	0.961220514	-0.105643756	normal	0.952431696	-0.177047041	normal	0.163677666	-0.464235825	normal	--	--	Molecular Function: voltage-gated calcium channel activity (GO:0005245);; Cellular Component: voltage-gated calcium channel complex (GO:0005891);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04862|0|pps:100993307|CACNB1; calcium channel, voltage-dependent, beta 1 subunit; K04862 voltage-dependent calcium channel beta-1 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Guanylate kinase;; Voltage gated calcium channel subunit beta domain 4Aa N terminal	Voltage-dependent L-type calcium channel subunit beta-1 GN=CACNB1 OS=Homo sapiens (Human) PE=1 SV=3	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: voltage-dependent L-type calcium channel subunit beta-1 isoform X2 [Tupaia chinensis]
ENSG00000067208(EVI5)	--	3.213297443	364	2.729049513	345	2.566095691	314	3.488273703	441	2.942448851	383	2.374132906	298	0.928740699	0.245067051	normal	0.959994824	0.128785521	normal	0.964902699	-0.083331639	normal	0.735613505	0.110730338	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	Ecotropic viral integration site 5 protein homolog GN=EVI5 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ecotropic viral integration site 5 protein homolog isoform X2 [Leptonychotes weddellii]
ENSG00000067221(STOML1)	--	4.8052855	161	3.159633085	131	5.0041591	180	8.563978523	298	7.696641307	278	7.324147942	279	0.005572735	0.851360703	normal	0.000160802	1.055539219	up	0.225927445	0.619762198	normal	0.000507562	0.836157758	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[C]	Energy production and conversion	SPFH domain / Band 7 family;; SCP-2 sterol transfer family	Stomatin-like protein 1 GN=STOML1 OS=Homo sapiens (Human) PE=1 SV=1	CI	Energy production and conversion;; Lipid transport and metabolism	PREDICTED: stomatin-like protein 1 isoform X1 [Leptonychotes weddellii]
ENSG00000067225(PKM)	--	1693.977485	84219	1695.431004	85278	1805.417865	90499	1841.854027	91588	1441.745686	70816	1735.917449	85975	0.999306044	0.090179	normal	0.996009493	-0.289519161	normal	0.999312471	-0.082274671	normal	0.797024318	-0.087329792	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: pyruvate kinase activity (GO:0004743);; Biological Process: glycolytic process (GO:0006096);; Molecular Function: potassium ion binding (GO:0030955);; 	"K00873|0|ptr:748700|PKM; pyruvate kinase, muscle; K00873 pyruvate kinase [EC:2.7.1.40] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Purine metabolism (ko00230);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; Type II diabetes mellitus (ko04930);; Viral carcinogenesis (ko05203);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	"Pyruvate kinase, barrel domain;; Pyruvate kinase, alpha/beta domain;; HpcH/HpaI aldolase/citrate lyase family"	Pyruvate kinase PKM GN=PKM OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: pyruvate kinase PKM isoform X5 [Canis lupus familiaris]
ENSG00000067248(DHX29)	--	17.11927907	1573	18.6373932	1702	18.38689654	1657	15.94806489	1470	17.87370378	1636	14.145126	1299	0.978377673	-0.128405	normal	0.982915963	-0.078413775	normal	0.836338357	-0.359092511	normal	0.330410534	-0.184481212	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[A]	RNA processing and modification	Helicase associated domain (HA2);; Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; AAA domain	ATP-dependent RNA helicase DHX29 GN=DHX29 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DHX29 [Tupaia chinensis]
ENSG00000067365(METTL22)	--	8.831284954	398	7.80526489	398	9.158489591	437	6.626727937	323	8.485027936	418	6.957320262	380	0.865157622	-0.330646578	normal	0.967993936	0.049125806	normal	0.943573985	-0.209148457	normal	0.579806989	-0.157846699	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	--	--	Putative methyltransferase	Methyltransferase-like protein 22 GN=METTL22 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: methyltransferase-like protein 22 isoform X1 [Galeopterus variegatus]
ENSG00000067369(TP53BP1)	--	14.48520287	2174	13.8631512	2258	14.56563852	2350	11.81510272	1828	11.41259529	1986	11.3523262	1885	0.940237044	-0.280701456	normal	0.970990379	-0.206458859	normal	0.904018195	-0.326152826	normal	0.103529658	-0.271962673	normal	--	--	--	--	--	[L]	"Replication, recombination and repair"	Tumour suppressor p53-binding protein-1 Tudor;; BRCA1 C Terminus (BRCT) domain	Tumor suppressor p53-binding protein 1 GN=TP53BP1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: tumor suppressor p53-binding protein 1 [Leptonychotes weddellii]
ENSG00000067445(TRO)	--	0.266977059	16	0.267057382	21	0.718299327	20	0.310940319	21	1.022031785	54	0.78388088	34	0.987036632	0.333472637	normal	0.134179237	1.281679491	normal	0.93992961	0.715333883	normal	0.231098047	0.915651324	normal	--	--	--	--	--	[S]	Function unknown	MAGE family	Trophinin GN=TRO OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: trophinin-like [Oryctolagus cuniculus]
ENSG00000067533(RRP15)	--	11.46787	691	13.05607	763	12.3087	680	12.01749	740	13.76924	788	11.98728	673	0.973668392	0.067861479	normal	0.975799455	0.025037185	normal	0.974877319	-0.023167892	normal	0.948801382	0.02305115	normal	--	--	Biological Process: rRNA processing (GO:0006364);; 	--	--	[S]	Function unknown	Rrp15p	RRP15-like protein GN=RRP15 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: RRP15-like protein isoform X2 [Vicugna pacos]
ENSG00000067560(RHOA)	--	207.1983645	6415	186.1701138	5780	191.3747395	5914	216.3538271	6722	202.9022847	6241	178.0057695	5496	0.994581995	0.03660045	normal	0.993091032	0.089258683	normal	0.992220689	-0.114013431	normal	0.985893701	0.005802357	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K04513|3.99368e-141|umr:103674825|RHOA; ras homolog family member A; K04513 Ras homolog gene family, member A (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Endocytosis (ko04144);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; TGF-beta signaling pathway (ko04350);; Axon guidance (ko04360);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Platelet activation (ko04611);; T cell receptor signaling pathway (ko04660);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Pancreatic secretion (ko04972);; Bacterial invasion of epithelial cells (ko05100);; Pertussis (ko05133);; Tuberculosis (ko05152);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Transforming protein RhoA (Precursor) GN=RHOA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: transforming protein RhoA isoform X1 [Ornithorhynchus anatinus]
ENSG00000067596(DHX8)	--	15.267	1798	14.579906	1823	15.95751	1829	15.8495672	2074	18.5798631	2246	16.2407148	2084	0.975606393	0.175051251	normal	0.942668246	0.279407666	normal	0.975008058	0.179869343	normal	0.237234931	0.211601094	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; 	K12818|0|pps:100980209|DHX8; DEAH (Asp-Glu-Ala-His) box polypeptide 8; K12818 ATP-dependent RNA helicase DHX8/PRP22 [EC:3.6.4.13] (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; S1 RNA binding domain;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; Type II/IV secretion system protein	ATP-dependent RNA helicase DHX8 GN=DHX8 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DHX8 [Bubalus bubalis]
ENSG00000067606(PRKCZ)	--	7.08565	280	6.17642805	230	5.622200248	286	6.528269866	291	7.688782355	304	5.773714057	242	0.967324952	0.024627506	normal	0.82334764	0.378838088	normal	0.930592939	-0.247872931	normal	0.904382229	0.051053469	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K18952|0|cjc:100394749|PRKCZ; protein kinase C, zeta; K18952 atypical protein kinase C zeta type [EC:2.7.11.13] (A)"	Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Endocytosis (ko04144);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Platelet activation (ko04611);; Insulin signaling pathway (ko04910);; Type II diabetes mellitus (ko04930)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PB1 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Protein kinase C terminal domain	Protein kinase C zeta type GN=PRKCZ OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: protein kinase C zeta type [Orycteropus afer afer]
ENSG00000067646(ZFY)	--	3.601133538	300	3.8716445	306	3.538919347	292	1.39668019	112	1.63224204	132	1.916484375	124	6.58E-09	-1.439721742	down	1.74E-06	-1.224924049	down	1.65E-06	-1.233812416	down	2.04E-08	-1.307908549	down	[R]	General function prediction only	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: metal ion binding (GO:0046872);; "	--	--	[R]	General function prediction only	"Zfx / Zfy transcription activation region;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc-finger domain"	Zinc finger Y-chromosomal protein GN=ZFY OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger X-chromosomal protein isoformX1 [Equus caballus]
ENSG00000067704(IARS2)	--	78.7406	5070	74.7291	4846	80.0227	5117	71.0076	4602	68.8692	4406	63.76	4093	0.987706149	-0.170502764	normal	0.988044231	-0.158699503	normal	0.935882607	-0.330321616	normal	0.230379445	-0.219923922	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA editing activity (GO:0002161);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01870|0|hsa:55699|IARS2, CAGSSS, ILERS; isoleucyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.5); K01870 isoleucyl-tRNA synthetase [EC:6.1.1.5] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (I, L, M and V);; Anticodon-binding domain of tRNA;; tRNA synthetases class I (M);; Zinc finger found in FPG and IleRS;; Leucyl-tRNA synthetase, Domain 2"	"Isoleucine--tRNA ligase, mitochondrial (Precursor) GN=IARS2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: isoleucine--tRNA ligase, mitochondrial [Ceratotherium simum simum]"
ENSG00000067715(SYT1)	--	9.545798414	770	10.17124672	679	10.97667184	809	13.7566149	1001	12.78696237	1064	19.274409	1109	0.837045327	0.347070518	normal	0.047837867	0.625466567	normal	0.559296043	0.446041332	normal	0.003271291	0.470614487	normal	[R]	General function prediction only	--	K15290|0|ptr:467079|SYT1; synaptotagmin I; K15290 synaptotagmin-1 (A)	Synaptic vesicle cycle (ko04721)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-1 GN=SYT1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-1 isoform X1 [Loxodonta africana]
ENSG00000067798(NAV3)	--	3.242786406	449	3.934588322	465	3.308902174	492	7.838576868	978	6.505751382	962	6.450369677	1057	1.02E-07	1.089699787	up	1.41E-06	1.025012966	up	6.72E-08	1.092607289	up	1.36E-12	1.071078371	up	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	Calponin homology (CH) domain;; AAA domain;; ATPase family associated with various cellular activities (AAA)	Neuron navigator 3 GN=NAV3 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: neuron navigator 3 isoform 1 [Trichechus manatus latirostris]
ENSG00000067829(IDH3G)	--	25.12189781	681	23.2941637	644	25.71164932	723	27.0798899	721	30.5270581	767	29.84142024	786	0.974286951	0.051399493	normal	0.940986019	0.23024339	normal	0.97071166	0.112017449	normal	0.590622666	0.130272813	normal	[CE]	Energy production and conversion;; Amino acid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00030|0|hsa:3421|IDH3G, H-IDHG; isocitrate dehydrogenase 3 (NAD+) gamma (EC:1.1.1.41); K00030 isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] (A)"	Citrate cycle (TCA cycle) (ko00020);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Isocitrate/isopropylmalate dehydrogenase	"Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial (Precursor) GN=IDH3G OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial isoform 1 [Canis lupus familiaris]"
ENSG00000067836(ROGDI)	--	9.140522467	290	6.604658012	230	7.427169772	249	5.36340666	167	7.370362293	245	6.133723045	208	0.009595063	-0.821226007	normal	0.964000029	0.069279937	normal	0.925440077	-0.266083001	normal	0.256364453	-0.331183163	normal	--	--	--	--	--	[S]	Function unknown	Rogdi leucine zipper containing protein	Protein rogdi homolog GN=ROGDI OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein rogdi homolog [Ceratotherium simum simum]
ENSG00000067840(PDZD4)	--	1.3995878	111	1.1544787	95	0.934107597	77	0.951829301	77	1.223081288	95	1.030706639	84	0.782905724	-0.549278122	normal	0.969964902	-0.021090823	normal	0.970638283	0.115075008	normal	0.77952704	-0.16596521	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K15682|0|pps:100972382|PDZD4; PDZ domain containing 4; K15682 ligand of Numb protein X 3/4 (A)	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain	PDZ domain-containing protein 4 GN=PDZD4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: PDZ domain-containing protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000067842(ATP2B3)	--	0.011676055	1	0	0	0	0	0.011661473	1	0.052530259	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: calcium-transporting ATPase activity (GO:0005388);; 	"K05850|0|pps:100978284|ATP2B3; ATPase, Ca++ transporting, plasma membrane 3; K05850 Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Salivary secretion (ko04970);; Pancreatic secretion (ko04972)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; Plasma membrane calcium transporter ATPase C terminal;; haloacid dehalogenase-like hydrolase;; Cation transporter/ATPase, N-terminus;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Plasma membrane calcium-transporting ATPase 3 GN=ATP2B3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: plasma membrane calcium-transporting ATPase 3 isoform X2 [Myotis brandtii]
ENSG00000067900(ROCK1)	--	11.01223051	1912	12.66636554	2233	12.03632889	2088	10.80840798	1923	10.9827263	1937	10.46033371	1849	0.986350871	-0.022537965	normal	0.965521262	-0.226421048	normal	0.974465669	-0.183526581	normal	0.461037493	-0.147997778	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Molecular Function: Rho GTPase binding (GO:0017048);; 	"K04514|0|hsa:6093|ROCK1, P160ROCK, ROCK-I; Rho-associated, coiled-coil containing protein kinase 1 (EC:2.7.11.1); K04514 Rho-associated protein kinase 1 [EC:2.7.11.1] (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Vascular smooth muscle contraction (ko04270);; TGF-beta signaling pathway (ko04350);; Axon guidance (ko04360);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Pathogenic Escherichia coli infection (ko05130);; Shigellosis (ko05131);; Salmonella infection (ko05132);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Rho Binding;; Hr1 repeat;; Kinase-like;; PH domain;; Protein kinase C terminal domain	Rho-associated protein kinase 1 GN=ROCK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho-associated protein kinase 1 [Camelus ferus] 
ENSG00000067955(CBFB)	--	18.383401	710	19.299277	781	18.07457576	737	23.22692825	946	23.47276957	882	20.11495653	738	0.763008561	0.382469785	normal	0.965565817	0.153749276	normal	0.976073318	-0.006322281	normal	0.390206105	0.181826874	normal	--	--	Molecular Function: transcription coactivator activity (GO:0003713);; Cellular Component: nucleus (GO:0005634);; 	--	--	[K]	Transcription	Core binding factor beta subunit	Core-binding factor subunit beta GN=CBFB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: core-binding factor subunit beta [Camelus dromedarius]
ENSG00000067992(PDK3)	--	10.69625	382	8.933	344	10.52969	375	6.97824	267	6.06728	238	6.828744805	283	0.332377785	-0.544928024	normal	0.360704416	-0.549949367	normal	0.740201238	-0.41245874	normal	0.026779253	-0.503535241	normal	[T]	Signal transduction mechanisms	--	"K00898|0|pps:100995647|PDK3; pyruvate dehydrogenase kinase, isozyme 3; K00898 pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2] (A)"	--	[T]	Signal transduction mechanisms	"Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (Precursor) GN=PDK3 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3, mitochondrial isoformX1 [Canis lupus familiaris]"
ENSG00000068001(HYAL2)	--	35.05679846	1159	32.50547347	1130	32.53606067	1095	36.05166401	1129	35.93822742	1185	28.94014052	936	0.979389031	-0.068575231	normal	0.980011019	0.047076205	normal	0.946453194	-0.234291511	normal	0.747209522	-0.080021926	normal	--	--	Molecular Function: hyalurononglucosaminidase activity (GO:0004415);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K01197|0|hsa:8692|HYAL2, LUCA2; hyaluronoglucosaminidase 2 (EC:3.2.1.35); K01197 hyaluronoglucosaminidase [EC:3.2.1.35] (A)"	Glycosaminoglycan degradation (ko00531)	--	--	Hyaluronidase	Hyaluronidase-2 (Precursor) GN=HYAL2 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: hyaluronidase-2 [Galeopterus variegatus] 
ENSG00000068024(HDAC4)	--	23.47953345	785	28.44839027	855	15.18002289	818	6.373510985	391	8.993307332	392	7.768493581	420	1.24E-06	-1.033428755	down	3.99E-08	-1.143431725	down	8.72E-06	-0.967459809	normal	3.57E-11	-1.051850939	down	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	"K11406|0|hsa:9759|HDAC4, AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA; histone deacetylase 4 (EC:3.5.1.98); K11406 histone deacetylase 4/5 [EC:3.5.1.98] (A)"	Alcoholism (ko05034);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206)	[B]	Chromatin structure and dynamics	Histone deacetylase domain;; Glutamine rich N terminal domain of histone deacetylase 4;; Arb2 domain	Histone deacetylase 4 GN=HDAC4 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 4 [Galeopterus variegatus]
ENSG00000068028(RASSF1)	--	9.380456314	294	8.642268699	282	8.760147414	285	10.77001641	344	10.25021729	319	6.568975734	208	0.947176237	0.194818238	normal	0.954826979	0.155649537	normal	0.678114877	-0.459801788	normal	0.998579403	-0.005893237	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	K09850|0|ptr:744944|RASSF1; Ras association (RalGDS/AF-6) domain family member 1; K09850 Ras association domain-containing protein 1 (A)	Ras signaling pathway (ko04014);; Hippo signaling pathway (ko04390);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Bladder cancer (ko05219);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Ras association domain-containing protein 1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras association domain-containing protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000068078(FGFR3)	--	0.990434763	78	0.741301482	61	0.958430888	60	0.571387582	45	0.677423231	54	0.311834343	25	0.544857189	-0.803280183	normal	0.970819161	-0.192208188	normal	0.11716213	-1.2221665	normal	0.158361145	-0.705065617	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05094|0|ptr:461067|FGFR3; fibroblast growth factor receptor 3; K05094 fibroblast growth factor receptor 3 [EC:2.7.10.1] (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Bladder cancer (ko05219);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Fibroblast growth factor receptor 3 (Precursor) GN=FGFR3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor receptor 3 isoform 1 [Ceratotherium simum simum]
ENSG00000068079(IFI35)	--	15.84458	343	19.31042	431	15.60758	348	16.05584	353	14.47779	311	24.65358	539	0.968609049	0.010580626	normal	0.501807436	-0.490165458	normal	0.085717832	0.620722333	normal	0.902498766	0.080392596	normal	--	--	--	--	--	--	--	Nmi/IFP 35 domain (NID);; Interferon-induced 35 kDa protein (IFP 35) N-terminus	Interferon-induced 35 kDa protein GN=IFI35 OS=Homo sapiens (Human) PE=1 SV=5	S	Function unknown	PREDICTED: interferon-induced 35 kDa protein [Galeopterus variegatus]
ENSG00000068097(HEATR6)	--	13.4992795	1008	11.21170685	935	10.91228918	945	12.07286499	928	10.5565181	878	13.62136155	1056	0.968929972	-0.149892974	normal	0.972622677	-0.111985027	normal	0.969233171	0.151702397	normal	0.9074175	-0.033914537	normal	--	--	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF4042);; HEAT repeats;; HEAT repeat;; HEAT-like repeat	HEAT repeat-containing protein 6 GN=HEATR6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: HEAT repeat-containing protein 6 [Equus caballus]
ENSG00000068120(COASY)	--	72.20943472	2459	62.91650932	2314	71.60873047	2654	76.22895875	2624	75.89427782	2699	71.29277409	2476	0.988041581	0.062825719	normal	0.975106765	0.200488138	normal	0.986121984	-0.108384543	normal	0.849499197	0.049385248	normal	[H]	Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: dephospho-CoA kinase activity (GO:0004140);; Molecular Function: ATP binding (GO:0005524);; Biological Process: biosynthetic process (GO:0009058);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; 	K02318|0|mcf:102124775|COASY; CoA synthase; K02318 phosphopantetheine adenylyltransferase / dephospho-CoA kinase [EC:2.7.7.3 2.7.1.24] (A)	Pantothenate and CoA biosynthesis (ko00770)	[R]	General function prediction only	Dephospho-CoA kinase;; Cytidylyltransferase;; AAA domain	Dephospho-CoA kinase GN=COASY OS=Homo sapiens (Human) PE=1 SV=4	H	Coenzyme transport and metabolism	PREDICTED: bifunctional coenzyme A synthase isoform X1 [Equus caballus] 
ENSG00000068137(PLEKHH3)	--	12.35321108	614	13.29156866	679	11.79255663	615	8.426438909	421	7.860770591	380	8.7283957	431	0.154555659	-0.573506187	normal	0.000411326	-0.856251969	normal	0.317845035	-0.519655305	normal	0.000214814	-0.652334912	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; Biological Process: signal transduction (GO:0007165);; 	--	--	[N]	Cell motility	MyTH4 domain;; FERM central domain;; Ras association (RalGDS/AF-6) domain	Pleckstrin homology domain-containing family H member 3 (Precursor) GN=PLEKHH3 OS=Homo sapiens (Human) PE=1 SV=2	N	Cell motility	PREDICTED: pleckstrin homology domain-containing family H member 3 [Galeopterus variegatus]
ENSG00000068305(MEF2A)	--	9.187619	670	16.54929105	867	8.986726812	638	8.776541012	652	11.00458043	699	8.37593761	671	0.972604702	-0.069958755	normal	0.861859792	-0.331520678	normal	0.972932973	0.064316232	normal	0.649282343	-0.126682262	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein dimerization activity (GO:0046983);; 	"K09260|0|hsa:4205|MEF2A, ADCAD1, RSRFC4, RSRFC9, mef2; myocyte enhancer factor 2A; K09260 MADS-box transcription enhancer factor 2A (A)"	cGMP-PKG signaling pathway (ko04022)	[K]	Transcription	SRF-type transcription factor (DNA-binding and dimerisation domain);; Holliday junction regulator protein family C-terminal repeat	Myocyte-specific enhancer factor 2A GN=MEF2A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myocyte-specific enhancer factor 2A isoform 1 [Ceratotherium simum simum]
ENSG00000068308(OTUD5)	--	29.6392394	1570	28.40946301	1556	28.59220193	1569	34.73504404	1897	38.53969566	2040	35.32326445	1898	0.955684055	0.241907243	normal	0.835443363	0.368986486	normal	0.944465457	0.266109664	normal	0.075490963	0.292469702	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K12655|0|bta:539145|OTUD5; OTU deubiquitinase 5 (EC:3.1.2.15); K12655 OTU domain-containing protein 5 [EC:3.4.19.12] (A)	RIG-I-like receptor signaling pathway (ko04622)	[TO]	"Signal transduction mechanisms;; Posttranslational modification, protein turnover, chaperones"	OTU-like cysteine protease	OTU domain-containing protein 5 GN=OTUD5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: OTU domain-containing protein 5 isoform X1 [Condylura cristata]
ENSG00000068323(TFE3)	--	28.69224	2058	29.51753	2156	28.488804	2158	33.37295	2369	32.33039	2358	28.78330986	2160	0.978093077	0.172083143	normal	0.984537719	0.107707726	normal	0.987563675	-0.006950126	normal	0.689336366	0.090720198	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K09105|0|pps:100984828|TFE3; transcription factor binding to IGHM enhancer 3; K09105 transcription factor E3 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Domain of unknown function (DUF3371);; Helix-loop-helix DNA-binding domain	Transcription factor E3 GN=TFE3 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: transcription factor E3 isoform 1 [Ceratotherium simum simum]
ENSG00000068354(TBC1D25)	--	4.860798164	365	4.757089	358	5.361572064	407	4.569245029	340	5.230811028	392	4.827265191	364	0.96011044	-0.132615402	normal	0.962698108	0.109027282	normal	0.954262984	-0.168718509	normal	0.858121989	-0.064784249	normal	[R]	General function prediction only	--	--	--	[T]	Signal transduction mechanisms	Rab-GTPase-TBC domain	TBC1 domain family member 25 GN=TBC1D25 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TBC1 domain family member 25 [Felis catus]
ENSG00000068366(ACSL4)	--	47.81325475	3733	43.35171302	3315	46.05417638	3516	71.22459372	5407	61.53075073	4753	103.6397307	7852	0.423507687	0.503487529	normal	0.463698607	0.498212222	normal	3.13E-10	1.150493683	up	0.05071055	0.749726791	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K01897|0|mcf:102132163|ACSL4; acyl-CoA synthetase long-chain family member 4; K01897 long-chain acyl-CoA synthetase [EC:6.2.1.3] (A)	Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	AMP-binding enzyme	Long-chain-fatty-acid--CoA ligase 4 GN=ACSL4 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: long-chain-fatty-acid--CoA ligase 4 isoform X1 [Felis catus]
ENSG00000068383(INPP5A)	--	8.542046999	430	8.196488453	416	8.604895058	438	9.316263978	453	9.993556196	506	9.298129966	472	0.969667163	0.044188296	normal	0.920789336	0.260268263	normal	0.966278842	0.099234427	normal	0.631604976	0.135430574	normal	--	--	--	"K01106|0|ptr:747128|INPP5A; inositol polyphosphate-5-phosphatase, 40kDa; K01106 inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[I]	Lipid transport and metabolism	Endonuclease/Exonuclease/phosphatase family;; Glycosyl hydrolase catalytic core	"Type I inositol 1,4,5-trisphosphate 5-phosphatase (Precursor) GN=INPP5A OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"type I inositol 1,4,5-trisphosphate 5-phosphatase [Canis lupus familiaris] "
ENSG00000068394(GPKOW)	--	11.6128	448	10.9168	429	12.8749	508	11.4126	445	14.1174	541	11.7244	455	0.96992109	-0.040386685	normal	0.880765519	0.312242335	normal	0.95643981	-0.16672865	normal	0.921405102	0.03643576	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13101|0|hsa:27238|GPKOW, GPATC5, GPATCH5, Spp2, T54; G patch domain and KOW motifs; K13101 G patch domain and KOW motifs-containing protein (A)"	--	[R]	General function prediction only	DExH-box splicing factor binding site;; KOW motif;; G-patch domain	G patch domain and KOW motifs-containing protein GN=GPKOW OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: G patch domain and KOW motifs-containing protein isoform 1 [Equus caballus]
ENSG00000068400(GRIPAP1)	--	15.73450907	1096	13.65012539	1151	13.69981209	1107	13.60097154	981	13.61314524	1046	14.79001047	1108	0.961625443	-0.190472591	normal	0.969016592	-0.159211999	normal	0.980765107	-0.006979253	normal	0.596312297	-0.118266544	normal	--	--	--	--	--	--	--	--	GRIP1-associated protein 1 GN=GRIPAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: GRIP1-associated protein 1 isoform X1 [Tupaia chinensis]
ENSG00000068438(FTSJ1)	--	18.45809901	693	16.585104	631	21.068868	796	26.72765055	1002	25.213124	952	22.958772	877	0.339747197	0.500196126	normal	0.138396359	0.570774069	normal	0.969711803	0.131279273	normal	0.019802142	0.396022522	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: methylation (GO:0032259);; 	K14864|0|pps:100974487|FTSJ1; FtsJ RNA methyltransferase homolog 1 (E. coli); K14864 tRNA (cytidine32/guanosine34-2'-O)-methyltransferase [EC:2.1.1.205] (A)	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	FtsJ-like methyltransferase	Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03162} OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase isoform X3 [Galeopterus variegatus] 
ENSG00000068489(PRR11)	--	40.81412725	3253	45.202758	3660	40.21455931	3242	44.60334601	3765	40.33880804	3203	38.8708362	3143	0.983233325	0.17996772	normal	0.977699034	-0.213751913	normal	0.990125429	-0.053008147	normal	0.923805752	-0.028188844	normal	--	--	--	--	--	--	--	--	Proline-rich protein 11 GN=PRR11 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: proline-rich protein 11 isoform X1 [Panthera tigris altaica] 
ENSG00000068615(REEP1)	--	0.5191942	20	0.275180456	16	0.232264432	13	1.122111414	52	0.876209116	51	0.897471558	54	0.164924893	1.284450123	normal	0.027114365	1.56409472	normal	0.001040391	1.927785692	up	0.001043547	1.65832773	up	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K17338|3.86771e-127|ocu:100359109|REEP1; receptor accessory protein 1; K17338 receptor expression-enhancing protein 1/2/3/4 (A)	--	[V]	Defense mechanisms	"TB2/DP1, HVA22 family"	Receptor expression-enhancing protein 1 GN=REEP1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: receptor expression-enhancing protein 1 isoform X3 [Oryctolagus cuniculus]
ENSG00000068650(ATP11A)	--	11.95420796	1669	13.966329	1883	12.280142	1758	10.0696343	1319	9.842686809	1304	9.523939	1283	0.814178186	-0.36998748	normal	0.173047882	-0.550980715	normal	0.50367342	-0.462237896	normal	0.001808875	-0.464331396	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|ptr:452677|ATP11A; ATPase, class VI, type 11A; K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase IH GN=ATP11A OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IH isoform 1 [Dasypus novemcinctus]
ENSG00000068654(POLR1A)	--	17.45968	4583	18.08782201	4748	19.00535435	4798	14.1090431	3617	14.19658062	3634	14.6235785	3787	0.879959918	-0.372190113	normal	0.820579562	-0.407039394	normal	0.913813825	-0.349544865	normal	0.016610845	-0.37719017	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K02999|0|hsa:25885|POLR1A, A190, RPA1, RPA194, RPO1-4, RPO14; polymerase (RNA) I polypeptide A, 194kDa (EC:2.7.7.6); K02999 DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020)	[K]	Transcription	"RNA polymerase Rpb1, domain 5;; RNA polymerase Rpb1, domain 2;; RNA polymerase Rpb1, domain 3;; RNA polymerase Rpb1, domain 4;; RNA polymerase Rpb1, domain 1"	DNA-directed RNA polymerase I subunit RPA1 GN=POLR1A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase I subunit RPA1 isoform 1 [Ceratotherium simum simum] 
ENSG00000068697(LAPTM4A)	--	164.439	3671	162.293	3653	159.271	3539	139.081	3133	139.417	3101	152.592	3408	0.965546973	-0.259342959	normal	0.966337344	-0.257658863	normal	0.990521337	-0.062680572	normal	0.299613905	-0.193027389	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K12387|1.07569e-138|ptr:459051|LAPTM4A; lysosomal protein transmembrane 4 alpha; K12387 lysosomal-associated transmembrane protein (A)	Lysosome (ko04142)	--	--	Golgi 4-transmembrane spanning transporter	Lysosomal-associated transmembrane protein 4A GN=UNQ1846/PRO3574 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lysosomal-associated transmembrane protein 4A [Galeopterus variegatus]
ENSG00000068724(TTC7A)	--	15.37378	1492	13.943087	1416	15.403742	1535	15.25273	1523	14.82469	1457	15.13913619	1505	0.984096439	-0.001162672	normal	0.98307464	0.019732279	normal	0.983805103	-0.036730064	normal	0.984925516	-0.007557837	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 7A GN=TTC7A OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	hypothetical protein PANDA_000214 [Ailuropoda melanoleuca]
ENSG00000068745(IP6K2)	--	32.68519752	983	31.0701884	919	28.083516	878	25.76197957	816	32.45335667	954	29.74923483	882	0.899998003	-0.298940789	normal	0.977907059	0.032445444	normal	0.978137551	-0.001730752	normal	0.721808438	-0.08902794	normal	--	--	"Molecular Function: inositol-1,4,5-trisphosphate 3-kinase activity (GO:0008440);; "	K07756|0|pps:100976000|IP6K2; inositol hexakisphosphate kinase 2; K07756 inositol-hexakisphosphate kinase [EC:2.7.4.21] (A)	--	[KIT]	Transcription;; Lipid transport and metabolism;; Signal transduction mechanisms	Inositol polyphosphate kinase	Inositol hexakisphosphate kinase 2 GN=IP6K2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: inositol hexakisphosphate kinase 2 [Camelus ferus] 
ENSG00000068781(STON1-GTF2A1L)	--	0.9841179	86	0.562809731	49	0.861727908	74	0.124873681	11	0.465685103	40	0.045439256	4	1.45E-10	-2.832425613	down	0.969016636	-0.303811487	normal	1.37E-12	-3.783059606	down	0.002642416	-1.947189915	down	[K]	Transcription	Cellular Component: transcription factor TFIIA complex (GO:0005672);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Transcription factor IIA, alpha/beta subunit;; Adaptor complexes medium subunit family"	Stonin-1 GN=STON1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TFIIA-alpha and beta-like factor-like isoform 1 [Ceratotherium simum simum]
ENSG00000068784(SRBD1)	--	6.688930786	504	6.402149409	480	6.34027705	470	4.359562309	330	4.070599905	306	4.99100953	376	0.066083632	-0.639361549	normal	0.04849559	-0.668268778	normal	0.863229989	-0.329033302	normal	0.006301723	-0.54372611	normal	[K]	Transcription	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[K]	Transcription	Tex-like protein N-terminal domain;; Helix-hairpin-helix motif;; S1 RNA binding domain;; Helix-hairpin-helix motif	S1 RNA-binding domain-containing protein 1 GN=SRBD1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: S1 RNA-binding domain-containing protein 1 isoform X2 [Equus przewalskii]
ENSG00000068796(KIF2A)	--	21.34845505	1584	19.96842572	1418	23.74455754	1590	23.4544937	1683	21.85188868	1539	17.99387316	1334	0.98395832	0.056577336	normal	0.980403473	0.096610224	normal	0.942249705	-0.261287854	normal	0.907236874	-0.033104992	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10393|0|hsa:3796|KIF2A, CDCBM3, HK2, KIF2; kinesin heavy chain member 2A; K10393 kinesin family member 2/24 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF2A GN=KIF2A OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF2A isoform X1 [Lipotes vexillifer]
ENSG00000068831(RASGRP2)	--	2.40324236	50	1.123995353	23	1.2443688	25	0.398856028	18	1.763191613	21	0.411543268	16	0.070541114	-1.428584184	normal	0.986533091	-0.142838428	normal	0.973106778	-0.605990562	normal	0.267002037	-0.855215925	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	K12361|0|mcf:102139509|RASGRP2; RAS guanyl releasing protein 2 (calcium and DAG-regulated); K12361 RAS guanyl-releasing protein 2 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Platelet activation (ko04611);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; EF-hand domain pair;; EF hand;; Phorbol esters/diacylglycerol binding domain (C1 domain);; EF hand;; EF-hand domain	RAS guanyl-releasing protein 2 GN=RASGRP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: RAS guanyl-releasing protein 2 isoform X2 [Mustela putorius furo] 
ENSG00000068878(PSME4)	--	20.7299	2585	22.224	2764	22.2754	2726	18.0556	2257	18.6377	2311	16.4722	2051	0.968483724	-0.226445942	normal	0.949532524	-0.279499414	normal	0.717959589	-0.418480926	normal	0.056223814	-0.308263168	normal	--	--	--	"K06699|0|hsa:23198|PSME4, PA200; proteasome (prosome, macropain) activator subunit 4; K06699 proteasome activator subunit 4 (A)"	Proteasome (ko03050)	[S]	Function unknown	Domain of unknown function (DUF3437);; HEAT repeat	Proteasome activator complex subunit 4 GN=PSME4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: proteasome activator complex subunit 4 [Odobenus rosmarus divergens]
ENSG00000068885(IFT80)	--	14.299728	812	11.703706	706	15.44105	801	12.472656	728	12.43500902	728	14.347841	779	0.957142961	-0.187997601	normal	0.974904449	0.022795624	normal	0.975934151	-0.048377735	normal	0.786760395	-0.074094412	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Intraflagellar transport protein 80 homolog GN=IFT80 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: intraflagellar transport protein 80 homolog [Leptonychotes weddellii]
ENSG00000068903(SIRT2)	--	21.74532516	747	20.01645216	717	20.891038	727	23.26575201	855	23.631234	827	34.568338	1260	0.963468309	0.163669096	normal	0.957909397	0.18412581	normal	0.00074048	0.78385118	normal	0.251641237	0.405164012	normal	[K]	Transcription	Molecular Function: NAD+ binding (GO:0070403);; 	K11412|0|mcf:101865690|SIRT2; NAD-dependent protein deacetylase sirtuin-2; K11412 NAD-dependent deacetylase sirtuin 2 [EC:3.5.1.-] (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	Sir2 family	NAD-dependent protein deacetylase sirtuin-2 GN=SIRT2 OS=Homo sapiens (Human) PE=1 SV=2	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: NAD-dependent protein deacetylase sirtuin-2 [Balaenoptera acutorostrata scammoni]
ENSG00000068912(ERLEC1)	--	59.08967	2158	57.14343055	2156	52.42046	1907	45.34838352	1710	42.766363	1594	48.95558	1808	0.837904065	-0.366237102	normal	0.565248814	-0.45675795	normal	0.984111899	-0.085132263	normal	0.060626339	-0.304531244	normal	--	--	--	K14008|0|ptr:470375|ERLEC1; endoplasmic reticulum lectin 1; K14008 endoplasmic reticulum lectin 1 (A)	Protein processing in endoplasmic reticulum (ko04141)	[R]	General function prediction only	Glucosidase II beta subunit-like protein;; Glucosidase II beta subunit-like protein	Endoplasmic reticulum lectin 1 (Precursor) GN=ERLEC1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: endoplasmic reticulum lectin 1 [Capra hircus]
ENSG00000068971(PPP2R5B)	--	5.445435	300	4.857743	260	3.9183034	228	5.838512	320	4.066365466	203	3.777282192	214	0.966286222	0.061969828	normal	0.839231082	-0.375976592	normal	0.963035826	-0.0990363	normal	0.811856679	-0.119486651	normal	--	--	Cellular Component: protein phosphatase type 2A complex (GO:0000159);; Biological Process: signal transduction (GO:0007165);; Molecular Function: protein phosphatase regulator activity (GO:0019888);; 	"K11584|0|hsa:5526|PPP2R5B, B56B, PR61B; protein phosphatase 2, regulatory subunit B', beta; K11584 serine/threonine-protein phosphatase 2A regulatory subunit B' (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Dopaminergic synapse (ko04728)	[T]	Signal transduction mechanisms	Protein phosphatase 2A regulatory B subunit (B56 family)	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform GN=PPP2R5B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform [Camelus ferus] 
ENSG00000068976(PYGM)	--	0.076770097	4	0.037903478	2	0.091030529	5	0.06262702	4	0.055929861	2	0.108790717	7	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: glycogen phosphorylase activity (GO:0008184);; 	"K00688|0|pps:100993679|PYGM; phosphorylase, glycogen, muscle; K00688 starch phosphorylase [EC:2.4.1.1] (A)"	Starch and sucrose metabolism (ko00500);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Carbohydrate phosphorylase	"Glycogen phosphorylase, muscle form GN=PYGM OS=Homo sapiens (Human) PE=1 SV=6"	G	Carbohydrate transport and metabolism	"PREDICTED: glycogen phosphorylase, muscle form [Ochotona princeps]"
ENSG00000068985(PAGE1)	--	0	0	0.107326	1	0	0	0.105376	1	0	0	0.325329	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GAGE protein	P antigen family member 1 GN=PAGE1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	hypothetical protein CB1_001030007 [Camelus ferus]
ENSG00000069011(PITX1)	--	16.54327793	571	11.488292	400	15.20633515	535	23.24466283	802	25.13668989	897	20.68313652	679	0.521481849	0.458234487	normal	4.07E-08	1.140725913	up	0.852068232	0.334739455	normal	0.003637653	0.637714439	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09356|2.86229e-167|cjc:100393481|PITX1; paired-like homeodomain 1; K09356 paired-like homeodomain transcription factor 1 (A)	--	[K]	Transcription	Homeobox domain;; OAR domain	Pituitary homeobox 1 GN=PITX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: pituitary homeobox 1 [Odobenus rosmarus divergens]
ENSG00000069020(MAST4)	--	1.907660555	310	1.909963582	371	1.614868146	355	2.072897453	366	2.261475632	432	2.731867199	597	0.943379119	0.207794554	normal	0.946310686	0.197439177	normal	0.007273917	0.739165682	normal	0.290513799	0.409558802	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08789|0|hsa:375449|MAST4; microtubule associated serine/threonine kinase family member 4 (EC:2.7.11.1); K08789 microtubule-associated serine/threonine kinase [EC:2.7.11.1] (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	Domain of unknown function (DUF1908);; Protein kinase domain;; Protein tyrosine kinase;; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Microtubule-associated serine/threonine-protein kinase 4 GN=MAST4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: microtubule-associated serine/threonine-protein kinase 4 [Equus caballus]
ENSG00000069122(ADGRF5)	--	0	0	0.037331892	4	0	0	0.009320851	1	0.01803734	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08458|0|hsa:221395|GPR116, KPG_001, ADGRF5; G protein-coupled receptor 116; K08458 G protein-coupled receptor 116 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; SEA domain;; Latrophilin/CL-1-like GPS domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Probable G-protein coupled receptor 116 (Precursor) GN=GPR116 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 116 isoform X3 [Oryctolagus cuniculus]
ENSG00000069188(SDK2)	--	2.1083033	550	1.158349264	320	1.516572499	313	0.343731543	69	0.6836959	174	0.278997766	60	0	-2.997468391	down	0.001940144	-0.89458569	normal	0	-2.362339417	down	0.001602404	-1.98640885	down	--	--	Molecular Function: protein binding (GO:0005515);; 	K16353|0|hsa:54549|SDK2; sidekick cell adhesion molecule 2; K16353 protein sidekick (A)	--	[T]	Signal transduction mechanisms	"Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Interferon-alpha/beta receptor, fibronectin type III"	Protein sidekick-2 (Precursor) GN=SDK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein sidekick-2 isoform X2 [Equus caballus]
ENSG00000069248(NUP133)	--	21.24810476	1197	15.43646499	1143	23.20466952	1292	23.402983	1393	21.13126041	1288	19.88033261	1191	0.966271966	0.187716337	normal	0.971970021	0.15069273	normal	0.975971019	-0.125570965	normal	0.776511807	0.070840059	normal	--	--	--	"K14300|0|hsa:55746|NUP133, hNUP133; nucleoporin 133kDa; K14300 nuclear pore complex protein Nup133 (A)"	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Non-repetitive/WGA-negative nucleoporin C-terminal;; Nup133 N terminal like	Nuclear pore complex protein Nup133 GN=NUP133 OS=Homo sapiens (Human) PE=1 SV=2	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup133 isoform X1 [Equus przewalskii]
ENSG00000069275(NUCKS1)	--	94.02444029	9666	96.256778	9824	90.4757963	9113	105.0250187	10881	104.4640756	10700	91.66175595	9433	0.99447786	0.139967011	normal	0.995281398	0.101786757	normal	0.995852728	0.04149239	normal	0.704654063	0.095044579	normal	--	--	--	--	--	--	--	--	Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 GN=NUCKS1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [Ceratotherium simum simum]
ENSG00000069329(VPS35)	--	31.25925805	3611	33.79734812	3880	31.58863022	3567	38.01419811	4394	36.6714956	4214	37.26594813	4295	0.971358501	0.252206784	normal	0.990303163	0.097670569	normal	0.968695464	0.259555055	normal	0.276762493	0.201244078	normal	--	--	"Molecular Function: protein transporter activity (GO:0008565);; Biological Process: protein transport (GO:0015031);; Cellular Component: retromer complex (GO:0030904);; Biological Process: retrograde transport, endosome to Golgi (GO:0042147);; "	K18468|0|pps:100973777|VPS35; vacuolar protein sorting 35 homolog (S. cerevisiae); K18468 vacuolar protein sorting-associated protein 35 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar protein sorting-associated protein 35	Vacuolar protein sorting-associated protein 35 GN=VPS35 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 35 [Mustela putorius furo] 
ENSG00000069345(DNAJA2)	--	31.47867067	1681	31.33449604	1689	32.05592548	1685	35.27305432	1888	36.62298035	1894	30.94283293	1615	0.979606739	0.136588936	normal	0.978586766	0.143718879	normal	0.983596427	-0.069442202	normal	0.760492236	0.072836711	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: heat shock protein binding (GO:0031072);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K09503|0|bta:360006|DNAJA2; DnaJ (Hsp40) homolog, subfamily A, member 2; K09503 DnaJ homolog subfamily A member 2 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain;; DnaJ central domain	DnaJ homolog subfamily A member 2 (Precursor) GN=DNAJA2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	dnaJ homolog subfamily A member 2 [Bos taurus] 
ENSG00000069399(BCL3)	--	71.16187065	2367	48.177845	1596	42.79499387	1402	46.25167833	1537	55.354161	1832	55.48027725	1875	0.016395149	-0.653244109	normal	0.973085345	0.177375326	normal	0.7116984	0.410728408	normal	0.929516481	-0.05395783	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K09258|0|ptr:744209|BCL3; B-cell CLL/lymphoma 3; K09258 B-cell CLL/lymphoma protein 3 (A)	TNF signaling pathway (ko04668)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	B-cell lymphoma 3 protein GN=BCL3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: B-cell lymphoma 3 protein [Lipotes vexillifer]
ENSG00000069424(KCNAB2)	--	21.27033506	1503	27.88182659	1980	25.49901051	1719	12.460725	957	12.52211439	835	18.20960006	1373	0.009081209	-0.681205654	normal	1.87E-11	-1.265542288	down	0.881617569	-0.332201628	normal	0.007355081	-0.737077651	normal	[C]	Energy production and conversion	--	"K04883|0|mcf:102115825|KCNAB2; potassium voltage-gated channel, shaker-related subfamily, beta member 2; K04883 potassium voltage-gated channel Shaker-related subfamily A, beta member 2 (A)"	--	[C]	Energy production and conversion	Aldo/keto reductase family	Voltage-gated potassium channel subunit beta-2 GN=KCNAB2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-gated potassium channel subunit beta-2 isoform X1 [Vicugna pacos]
ENSG00000069431(ABCC9)	--	0.638546063	86	0.795476764	107	0.841597001	111	0.780093007	106	0.791015412	107	0.810119558	110	0.951950963	0.26652846	normal	0.968816491	-0.02112795	normal	0.969823933	-0.021059375	normal	0.92119102	0.066599762	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05033|0|ptr:465338|ABCC9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; K05033 ATP-binding cassette subfamily C (CFTR/MRP) member 9 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter transmembrane region;; ABC transporter;; AAA domain;; AAA domain	ATP-binding cassette sub-family C member 9 GN=ABCC9 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family C member 9 isoform X2 [Orycteropus afer afer]
ENSG00000069482(GAL)	--	0.770282	8	0.649564	7	1.78942	19	5.78554	62	4.69666	49	3.00167	32	3.70E-07	2.708082732	up	3.29E-05	2.549813904	up	0.94872274	0.700403054	normal	0.000405702	2.051156111	up	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	"K05244|8.17677e-55|hsa:51083|GAL, GAL-GMAP, GALN, GLNN, GMAP; galanin/GMAP prepropeptide; K05244 galanin (A)"	--	--	--	Galanin message associated peptide (GMAP);; Galanin	Galanin message-associated peptide (Precursor) GN=GAL OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: galanin peptides [Tupaia chinensis]
ENSG00000069493(CLEC2D)	--	4.503100475	71	1.37737941	60	1.002099736	66	1.528580693	67	0.726177594	60	1.910754557	118	0.973229998	-0.11199478	normal	0.975340273	-0.020899792	normal	0.221698059	0.815790821	normal	0.668074155	0.295159405	normal	--	--	--	"K10072|8.03948e-145|hsa:29121|CLEC2D, CLAX, LLT1, OCIL; C-type lectin domain family 2, member D; K10072 C-type lectin domain family 2 member D (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; UL45 protein	C-type lectin domain family 2 member D GN=CLEC2D OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: C-type lectin domain family 2 member D isoform X1 [Felis catus]
ENSG00000069509(FUNDC1)	--	15.87069	311	17.50719	351	17.96023532	360	14.4124775	292	15.834172	311	16.19968	319	0.96098803	-0.121160573	normal	0.946240542	-0.195089386	normal	0.950699271	-0.181919556	normal	0.579236144	-0.169336088	normal	--	--	--	K17986|5.33215e-103|ptr:740893|FUNDC1; FUN14 domain containing 1; K17986 FUN14 domain-containing protein 1 (A)	--	[S]	Function unknown	FUN14 family	FUN14 domain-containing protein 1 GN=FUNDC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: FUN14 domain-containing protein 1 [Oryctolagus cuniculus]
ENSG00000069535(MAOB)	--	0.0590859	3	0.0578365	3	0.0384723	1	0.0586257	3	0.173367	8	0.0588462	3	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; Molecular Function: FAD binding (GO:0071949);; 	K00274|0|hsa:4129|MAOB; monoamine oxidase B (EC:1.4.3.4); K00274 monoamine oxidase [EC:1.4.3.4] (A)	"Glycine, serine and threonine metabolism (ko00260);; Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Tryptophan metabolism (ko00380);; Drug metabolism - cytochrome P450 (ko00982);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)"	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Flavin containing amine oxidoreductase;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase;; Thi4 family;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain	Amine oxidase [flavin-containing] B GN=MAOB OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	amine oxidase [flavin-containing] B [Canis lupus familiaris] 
ENSG00000069667(RORA)	--	3.151087558	41	3.56778739	38	2.82746873	28	9.33940401	63	6.270210814	47	9.286648694	78	0.902275917	0.571505883	normal	0.972291889	0.275366275	normal	0.004306604	1.421861902	up	0.11673534	0.791922671	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K08532|0|mcf:102142259|RORA; RAR-related orphan receptor A; K08532 RAR-related orphan receptor alpha (A)	Circadian rhythm (ko04710);; Inflammatory bowel disease (IBD) (ko05321)	[K]	Transcription	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Nuclear receptor ROR-alpha GN=RORA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	hypothetical protein PANDA_012073 [Ailuropoda melanoleuca]
ENSG00000069696(DRD4)	--	0.444340071	26	0.36769323	22	0.373900207	22	0.425304672	25	0.816034	39	0.423533	20	0.986611529	-0.082446694	normal	0.903596212	0.764607093	normal	0.987809704	-0.135987318	normal	0.800386331	0.241480062	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04147|5.19158e-107|ptr:449578|DRD4; dopamine receptor D4; K04147 dopamine receptor D4 (A)	Neuroactive ligand-receptor interaction (ko04080);; Dopaminergic synapse (ko04728)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	D(4) dopamine receptor GN=DRD4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: D(4) dopamine receptor [Ochotona princeps]
ENSG00000069702(TGFBR3)	--	8.81765622	1012	6.952294463	796	8.670815422	980	3.722207762	376	3.460994654	393	3.712957388	425	4.75E-14	-1.455456216	down	1.64E-06	-1.036801684	down	1.22E-09	-1.210689377	down	2.39E-14	-1.244050387	down	--	--	--	"K05843|0|ggo:101144262|TGFBR3; transforming growth factor beta receptor type 3 isoform 1; K05843 transforming growth factor, beta receptor III (A)"	--	--	--	Zona pellucida-like domain	Transforming growth factor beta receptor type 3 (Precursor) GN=TGFBR3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: transforming growth factor beta receptor type 3 isoform X1 [Canis lupus familiaris]
ENSG00000069712(KIAA1107)	--	1.421002387	176	0.89614549	121	1.431280312	176	1.00683714	119	0.823692253	96	0.955994129	117	0.508972509	-0.589148015	normal	0.919726925	-0.350398689	normal	0.508241775	-0.591085463	normal	0.121222895	-0.531610271	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4596)	Uncharacterized protein KIAA1107 GN=KIAA1107 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA1107 homolog [Galeopterus variegatus]
ENSG00000069764(PLA2G10)	--	0.163087	2	0.0778512	1	0	0	0	0	0.0791145	0	0.15902	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipase A2 activity (GO:0004623);; Biological Process: phospholipid metabolic process (GO:0006644);; Biological Process: arachidonic acid secretion (GO:0050482);; 	"K01047|9.72115e-97|hsa:8399|PLA2G10, GXPLA2, GXSPLA2, SPLA2; phospholipase A2, group X (EC:3.1.1.4); K01047 secretory phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; Pancreatic secretion (ko04972);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Phospholipase A2	Group 10 secretory phospholipase A2 (Precursor) GN=PLA2G10 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: group 10 secretory phospholipase A2 [Felis catus]
ENSG00000069812(HES2)	--	2.25602585	46	0.742159338	27	0.642644912	34	0.711966775	32	1.487273585	39	0.463719052	20	0.946682827	-0.53293163	normal	0.9619225	0.486317349	normal	0.935893261	-0.730980801	normal	0.761901642	-0.25586637	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09087|1.037e-83|hsa:54626|HES2, bHLHb40; hes family bHLH transcription factor 2; K09087 hairy and enhancer of split 2/6/7 (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain;; Hairy Orange	Transcription factor HES-2 GN=HES2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	transcription factor HES-2 isoform 1 [Bos taurus] 
ENSG00000069849(ATP1B3)	--	70.9828118	1912	64.03451415	1732	64.42499839	1749	80.50186052	2229	73.14174457	1983	82.38841781	2258	0.973963326	0.190340072	normal	0.975002104	0.173677384	normal	0.852527303	0.359949128	normal	0.162340569	0.241422424	normal	--	--	Cellular Component: sodium:potassium-exchanging ATPase complex (GO:0005890);; Biological Process: potassium ion transport (GO:0006813);; Biological Process: sodium ion transport (GO:0006814);; 	K01540|0|mcf:101865296|uncharacterized LOC101865296; K01540 sodium/potassium-transporting ATPase subunit beta (A)	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Insulin secretion (ko04911);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Proximal tubule bicarbonate reclamation (ko04964);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Carbohydrate digestion and absorption (ko04973);; Protein digestion and absorption (ko04974);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Sodium / potassium ATPase beta chain	Sodium/potassium-transporting ATPase subunit beta-3 GN=ATP1B3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	sodium/potassium-transporting ATPase subunit beta-3 [Oryctolagus cuniculus] 
ENSG00000069869(NEDD4)	--	28.72715441	3297	38.424836	4267	33.80671373	3793	47.94909731	5634	40.290681	4709	48.606799	5729	0.001675081	0.741906015	normal	0.990091788	0.120731312	normal	0.104606307	0.586460954	normal	0.003557801	0.479698367	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	"K10591|0|hsa:4734|NEDD4, NEDD4-1, RPF1; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (EC:6.3.2.-); K10591 E3 ubiquitin-protein ligase NEDD4 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain	E3 ubiquitin-protein ligase NEDD4 GN=NEDD4 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase NEDD4 isoform X1 [Galeopterus variegatus]
ENSG00000069943(PIGB)	--	10.13861	278	9.226326	269	7.47498	197	12.00163	304	11.571329	336	12.0543	330	0.963401289	0.097638064	normal	0.89968588	0.297927232	normal	0.032997984	0.731593084	normal	0.160031677	0.361228162	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K05286|0|hsa:9488|PIGB, GPI-MT-III, PIG-B; phosphatidylinositol glycan anchor biosynthesis, class B; K05286 phosphatidylinositol glycan, class B [EC:2.4.1.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[MO]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	Alg9-like mannosyltransferase family	GPI mannosyltransferase 3 GN=PIGB OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: GPI mannosyltransferase 3 [Ceratotherium simum simum]
ENSG00000069956(MAPK6)	--	26.78632	2289	27.35145	2322	27.91476	2327	33.0444	2848	28.22689	2408	31.40018	2679	0.946227115	0.284228112	normal	0.987810012	0.031021023	normal	0.976256116	0.194813842	normal	0.364436297	0.172277309	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06855|0|ptr:453439|MAPK6; mitogen-activated protein kinase 6; K06855 mitogen-activated protein kinase 4/6 [EC:2.7.11.24] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase 6 GN=MAPK6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 6 [Panthera tigris altaica] 
ENSG00000069966(GNB5)	--	33.18478606	1259	34.17907598	1285	36.79172115	1385	31.53610283	1232	30.61987135	1178	29.38460041	1127	0.9807146	-0.062031761	normal	0.972778541	-0.146675017	normal	0.904374409	-0.305319639	normal	0.379641471	-0.172943046	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K04539|0|mmu:14697|Gnb5, GBS, Gbeta5, flr; guanine nucleotide binding protein (G protein), beta 5; K04539 guanine nucleotide-binding protein subunit beta-5 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[R]	General function prediction only	"WD domain, G-beta repeat"	Guanine nucleotide-binding protein subunit beta-5 GN=GNB5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit beta-5 isoform X2 [Sus scrofa]
ENSG00000069974(RAB27A)	--	45.86619085	2628	46.89926179	2514	45.83207734	2429	50.63682332	2815	50.19002782	2828	64.0086099	3992	0.988461183	0.068298799	normal	0.983203374	0.148286774	normal	0.004086619	0.708110432	normal	0.277129855	0.327555244	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07885|1.02355e-164|hsa:5873|RAB27A, GS2, HsT18676, RAB27, RAM; RAB27A, member RAS oncogene family; K07885 Ras-related protein Rab-27A (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-27A GN=RAB27A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-27A [Chrysochloris asiatica]
ENSG00000069998(HDHD5)	--	19.41579701	636	18.65137056	631	18.3738501	625	23.20087639	761	19.68791263	639	19.51094076	642	0.941936608	0.227534413	normal	0.973691311	-0.003242909	normal	0.973968908	0.030353199	normal	0.745796906	0.088283743	normal	[G]	Carbohydrate transport and metabolism	--	--	--	[R]	General function prediction only	Haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like	Cat eye syndrome critical region protein 5 (Precursor) GN=CECR5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cat eye syndrome critical region protein 5 [Trichechus manatus latirostris]
ENSG00000070010(UFD1L)	--	43.83332792	890	52.94494174	920	50.67963171	878	44.47698686	930	46.35019901	825	39.61904457	895	0.978039584	0.032538167	normal	0.96135613	-0.178356509	normal	0.978079606	0.019342303	normal	0.88850861	-0.04195668	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; 	K14016|0|pps:100978350|UFD1L; ubiquitin fusion degradation 1 like (yeast); K14016 ubiquitin fusion degradation protein 1 (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin fusion degradation protein UFD1	Ubiquitin fusion degradation protein 1 homolog GN=UFD1L OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin fusion degradation protein 1 homolog isoform X1 [Myotis brandtii] 
ENSG00000070018(LRP6)	--	13.08059334	2278	15.66358	2571	14.6535467	2506	16.599193	2705	17.232395	2805	16.6477401	2877	0.97149093	0.216894215	normal	0.986526391	0.10418592	normal	0.978077493	0.190779836	normal	0.380800599	0.168469821	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K03068|0|hsa:4040|LRP6, ADCAD2; low density lipoprotein receptor-related protein 6; K03068 low density lipoprotein receptor-related protein 5/6 (A)"	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; Low-density lipoprotein receptor domain class A;; SMP-30/Gluconolaconase/LRE-like region;; Arylesterase;; NHL repeat	Low-density lipoprotein receptor-related protein 6 (Precursor) GN=LRP6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 6 isoform 1 [Odobenus rosmarus divergens]
ENSG00000070047(PHRF1)	--	13.617163	1819	14.1944218	1934	13.67244001	1903	15.891082	2136	16.389108	2195	13.10558	1774	0.970993306	0.20077722	normal	0.978419436	0.161088292	normal	0.982462671	-0.10947087	normal	0.69718724	0.088552035	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K17586|0|hsa:57661|PHRF1, PPP1R125, RNF221; PHD and ring finger domains 1; K17586 PHD and RING finger domain-containing protein 1 (A)"	--	[R]	General function prediction only	"PHD-finger;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	PHD and RING finger domain-containing protein 1 GN=PHRF1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: PHD and RING finger domain-containing protein 1 isoform X4 [Tupaia chinensis]
ENSG00000070061(IKBKAP)	--	20.06223138	1906	19.49220074	1861	21.84503343	2127	21.06408254	1980	19.23675284	1754	18.13675002	1715	0.986453243	0.024100986	normal	0.982113356	-0.106766479	normal	0.907706229	-0.318650078	normal	0.5139969	-0.134685003	normal	[K]	Transcription	"Biological Process: tRNA wobble uridine modification (GO:0002098);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Cellular Component: Elongator holoenzyme complex (GO:0033588);; "	"K11373|0|hsa:8518|IKBKAP, DYS, ELP1, FD, IKAP, IKI3, TOT1; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein; K11373 elongator complex protein 1 (A)"	--	[K]	Transcription	IKI3 family	Elongator complex protein 1 GN=IKBKAP OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: elongator complex protein 1 [Galeopterus variegatus]
ENSG00000070081(NUCB2)	--	23.4506881	853	25.27765579	802	22.55567827	839	22.83699669	783	18.32436208	789	21.59236934	733	0.965659191	-0.154075905	normal	0.975545079	-0.044918098	normal	0.953330041	-0.202757732	normal	0.562078871	-0.135020423	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[R]	General function prediction only	EF-hand domain pair;; EF hand;; EF-hand domain	Nesfatin-1 (Precursor) GN=NUCB2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: nucleobindin-2 isoform X1 [Orycteropus afer afer]
ENSG00000070087(PFN2)	--	152.7786269	3708	148.5331014	3659	147.2964804	3620	157.1768695	3822	139.5335416	3323	116.2390058	2797	0.991766384	0.012849027	normal	0.985104224	-0.160320116	normal	0.847230161	-0.380219659	normal	0.396302255	-0.16634563	normal	--	--	--	K05759|9.44851e-98|mcc:713460|uncharacterized LOC713460; K05759 profilin (A)	Rap1 signaling pathway (ko04015);; Regulation of actin cytoskeleton (ko04810);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	Profilin	Profilin-2 GN=PFN2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: profilin-2 isoform 1 [Dasypus novemcinctus]
ENSG00000070159(PTPN3)	--	12.23847051	1626	12.0841527	1599	12.9875009	1709	9.91418246	1312	8.112035	1068	9.307340557	1240	0.867589294	-0.340033291	normal	0.064875395	-0.602981981	normal	0.464748575	-0.470612654	normal	0.001734281	-0.468112268	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18027|0|pps:100985380|PTPN3; protein tyrosine phosphatase, non-receptor type 3; K18027 tyrosine-protein phosphatase non-receptor type 3 [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; FERM N-terminal domain;; FERM C-terminal PH-like domain;; FERM central domain;; PDZ domain (Also known as DHR or GLGF);; Dual specificity phosphatase, catalytic domain"	Tyrosine-protein phosphatase non-receptor type 3 GN=PTPN3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 3 isoform X1 [Felis catus]
ENSG00000070182(SPTB)	--	0.888037437	183	0.65795662	149	0.802927621	186	0.811988127	184	1.43033398	289	1.4931207	302	0.966970199	-0.022779418	normal	0.001689901	0.927454757	normal	0.082808346	0.686532434	normal	0.130424689	0.56179183	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K06115|0|pps:100990986|SPTB; spectrin, beta, erythrocytic; K06115 spectrin beta (A)"	--	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Pleckstrin homology domain;; CAMSAP CH domain;; PH domain	"Spectrin beta chain, erythrocytic GN=SPTB OS=Homo sapiens (Human) PE=1 SV=5"	Z	Cytoskeleton	"PREDICTED: spectrin beta chain, erythrocytic [Condylura cristata]"
ENSG00000070190(DAPP1)	--	0	0	0	0	0	0	0.020446758	1	0.040104198	1	0.061340097	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K12229|0|pps:100974297|DAPP1; dual adaptor of phosphotyrosine and 3-phosphoinositides; K12229 dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide (A)	B cell receptor signaling pathway (ko04662)	--	--	SH2 domain;; PH domain	Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide GN=DAPP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide [Mustela putorius furo] 
ENSG00000070214(SLC44A1)	--	29.58513893	2500	22.43557871	2065	24.472575	2225	26.69700871	2450	30.98723201	2723	29.05986442	2508	0.987902413	-0.059941395	normal	0.838526183	0.377387284	normal	0.980127333	0.164335308	normal	0.423430446	0.156809524	normal	--	--	--	"K06515|0|hsa:23446|SLC44A1, CD92, CDW92, CHTL1, CTL1; solute carrier family 44 (choline transporter), member 1; K06515 solute carrier family 44 (choline transporter-like protein), member 1 (A)"	Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Plasma-membrane choline transporter	Choline transporter-like protein 1 GN=SLC44A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: choline transporter-like protein 1 [Oryctolagus cuniculus]
ENSG00000070269(TMEM260)	--	7.0227674	444	5.710732	346	6.806078404	382	6.49676201	411	6.678258	410	8.216752147	509	0.96000187	-0.141743549	normal	0.937729334	0.222530951	normal	0.728643532	0.404410069	normal	0.563103953	0.161881374	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2723);; Dolichyl-phosphate-mannose-protein mannosyltransferase	Transmembrane protein 260 GN=TMEM260 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane protein 260 isoform X1 [Galeopterus variegatus]
ENSG00000070366(SMG6)	--	14.5256637	1545	14.07295478	1559	13.60056278	1677	17.83852304	1719	15.50663041	1669	11.55128567	1472	0.979816741	0.123014435	normal	0.982608038	0.0768644	normal	0.967968103	-0.196207459	normal	0.997812236	0.00215451	normal	--	--	--	K11124|0|ptr:454417|SMG6; SMG6 nonsense mediated mRNA decay factor; K11124 protein SMG6 [EC:3.1.-.-] (A)	mRNA surveillance pathway (ko03015)	--	--	Est1 DNA/RNA binding domain;; PIN domain;; Telomerase activating protein Est1	Telomerase-binding protein EST1A GN=SMG6 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: telomerase-binding protein EST1A isoform X2 [Felis catus]
ENSG00000070367(EXOC5)	--	22.92282546	2013	25.94276542	2329	26.55326538	2319	26.58254308	2415	20.17253711	1873	24.84018783	2238	0.965016647	0.231682139	normal	0.895976381	-0.3355428	normal	0.987173217	-0.059544696	normal	0.844306608	-0.050987361	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: exocytosis (GO:0006887);; Biological Process: vesicle docking (GO:0048278);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec10	Exocyst complex component 5 GN=EXOC5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 5 [Galeopterus variegatus]
ENSG00000070371(CLTCL1)	--	3.661586244	407	2.578478097	269	3.65090091	370	8.628948003	918	10.53657386	1156	9.316118735	944	2.34E-08	1.139693375	up	0	2.075908796	up	1.14E-11	1.339418341	up	1.35E-13	1.507962997	up	--	--	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: clathrin coat of trans-Golgi network vesicle (GO:0030130);; Cellular Component: clathrin coat of coated pit (GO:0030132);; 	"K04646|0|pps:100976560|CLTCL1; clathrin, heavy chain-like 1; K04646 clathrin heavy chain (A)"	Lysosome (ko04142);; Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016);; Bacterial invasion of epithelial cells (ko05100)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Region in Clathrin and VPS;; Clathrin propeller repeat;; Clathrin-H-link;; Clathrin, heavy-chain linker"	Clathrin heavy chain 2 GN=CLTCL1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: clathrin heavy chain 2 isoform X2 [Mustela putorius furo] 
ENSG00000070388(FGF22)	--	0.092172106	2	0.347183	8	0.08669823	1	0.136084778	3	0.133032183	2	0.2706696	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|6.21819e-95|pps:100968963|FGF22; fibroblast growth factor 22; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 22 (Precursor) GN=FGF22 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 22 [Leptonychotes weddellii]
ENSG00000070404(FSTL3)	--	51.6230196	2110	51.777001	2324	48.60289344	2127	110.695913	5066	106.420402	4792	86.06017138	3775	8.67E-12	1.232175025	up	1.58E-07	1.022118356	up	0.000140222	0.818922226	normal	1.81E-08	1.033009097	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Follistatin/Osteonectin-like EGF domain	Follistatin-related protein 3 (Precursor) GN=FSTL3 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	follistatin-related protein 3 precursor [Bos taurus] 
ENSG00000070413(DGCR2)	--	13.65992	1171	14.47567268	1261	12.13990275	1061	18.928386	1612	19.36807891	1635	16.30691047	1395	0.632579668	0.429796003	normal	0.851867724	0.35292318	normal	0.766672007	0.38606769	normal	0.01273461	0.388454605	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Lectin C-type domain;; Low-density lipoprotein receptor domain class A;; UL45 protein	Integral membrane protein DGCR2/IDD (Precursor) GN=DGCR2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: integral membrane protein DGCR2/IDD isoform X1 [Mustela putorius furo] 
ENSG00000070423(RNF126)	--	24.23443588	692	18.55841314	515	19.711921	574	21.62306345	625	28.02873721	782	17.27939	484	0.957540067	-0.177333565	normal	0.132397442	0.579778714	normal	0.925761117	-0.253606557	normal	0.902498766	0.064746975	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: metal ion binding (GO:0046872);; 	K11982|0|hsa:55658|RNF126; ring finger protein 126; K11982 E3 ubiquitin-protein ligase RNF115/126 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; zinc-finger;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Anaphase-promoting complex subunit 11 RING-H2 finger"	E3 ubiquitin-protein ligase RNF126 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF126 [Chrysochloris asiatica]
ENSG00000070444(MNT)	--	9.322118289	1114	13.67818567	1651	10.555171	1253	7.159335444	833	6.992902371	814	13.87618488	1651	0.542942755	-0.449473322	normal	2.06E-07	-1.040279365	down	0.767259235	0.389251747	normal	0.658008667	-0.304249588	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09115|8.02066e-166|hsa:4335|MNT, MAD6, MXD6, ROX, bHLHd3; MAX network transcriptional repressor; K09115 MAX-binding protein (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Max-binding protein MNT GN=MNT OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: max-binding protein MNT [Orycteropus afer afer]
ENSG00000070476(ZXDC)	--	7.09060477	986	6.004371676	971	5.69260659	892	5.89941579	911	6.230808702	896	8.140351639	1225	0.96945088	-0.144734132	normal	0.969958525	-0.137176635	normal	0.549037015	0.448722899	normal	0.845964132	0.069334231	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein ZXDC GN=ZXDC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein ZXDC [Odobenus rosmarus divergens]
ENSG00000070495(JMJD6)	--	20.457182	749	24.88833353	938	25.50474201	939	26.473927	1030	25.994392	1019	24.870919	921	0.626279785	0.428022998	normal	0.97497819	0.09791618	normal	0.978281839	-0.036156645	normal	0.466930052	0.156246802	normal	--	--	--	K11323|0|pps:100989138|JMJD6; jumonji domain containing 6; K11323 histone arginine demethylase JMJD6 [EC:1.14.11.-] (A)	--	[BT]	Chromatin structure and dynamics;; Signal transduction mechanisms	"JmjC domain, hydroxylase;; Cupin-like domain"	Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 GN=JMJD6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 isoform X1 [Pteropus alecto] 
ENSG00000070501(POLB)	--	13.09839893	238	13.24933398	240	12.99058604	233	10.04847866	215	10.23187869	199	12.0142355	231	0.952601254	-0.176259289	normal	0.91359816	-0.289684616	normal	0.966889976	-0.0205943	normal	0.658860259	-0.161610225	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Molecular Function: DNA polymerase activity (GO:0034061);; 	"K02330|0|ptr:737210|POLB; polymerase (DNA directed), beta; K02330 DNA polymerase beta [EC:2.7.7.7 4.2.99.-] (A)"	Base excision repair (ko03410);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[L]	"Replication, recombination and repair"	DNA polymerase beta palm;; Fingers domain of DNA polymerase lambda;; Helix-hairpin-helix domain;; DNA polymerase beta thumb;; Helix-hairpin-helix domain	DNA polymerase beta GN=POLB OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase beta [Mustela putorius furo] 
ENSG00000070526(ST6GALNAC1)	--	0	0	0.017762869	1	0.0680694	3	0.017765676	1	0.442078	0	0.03484933	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03479|0|ggo:101131564|ST6GALNAC1; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 isoform 1; K03479 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7A) [EC:2.4.99.3] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 GN=ST6GALNAC1 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 [Galeopterus variegatus]"
ENSG00000070540(WIPI1)	--	17.70518	585	13.554624	424	15.09665	487	10.08177	320	13.7362	450	13.094202	418	0.000164236	-0.897956631	normal	0.967830997	0.064211856	normal	0.937092745	-0.227945446	normal	0.220464286	-0.352897235	normal	[R]	General function prediction only	--	"K17908|0|hsa:55062|WIPI1, ATG18, ATG18A, WIPI49; WD repeat domain, phosphoinositide interacting 1; K17908 autophagy-related protein 18 (A)"	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat domain phosphoinositide-interacting protein 1 GN=WIPI1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: WD repeat domain phosphoinositide-interacting protein 1 [Mustela putorius furo]
ENSG00000070601(FRMPD1)	--	0.035783754	4	0.017932512	2	0.008792533	0	0.018016134	2	0.008691944	0	0.008863734	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	FERM central domain;; PDZ domain (Also known as DHR or GLGF);; FERM N-terminal domain	FERM and PDZ domain-containing protein 1 GN=FRMPD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: FERM and PDZ domain-containing protein 1 [Trichechus manatus latirostris]
ENSG00000070610(GBA2)	--	13.179194	733	13.60508486	800	15.06823016	867	13.035508	778	15.494328	889	16.743365	1006	0.975011166	0.055012762	normal	0.969398264	0.130522729	normal	0.955429137	0.205901268	normal	0.557852277	0.135228119	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; "	"K17108|0|hsa:57704|GBA2, NLGase, SPG46; glucosidase, beta (bile acid) 2 (EC:3.2.1.45); K17108 non-lysosomal glucosylceramidase [EC:3.2.1.45] (A)"	Other glycan degradation (ko00511);; Sphingolipid metabolism (ko00600)	[G]	Carbohydrate transport and metabolism	"Protein of unknown function, DUF608;; beta-Glucocerebrosidase 2 N terminal"	Non-lysosomal glucosylceramidase GN=GBA2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: non-lysosomal glucosylceramidase isoform X1 [Galeopterus variegatus]
ENSG00000070614(NDST1)-2	--	25.79060832	3795	27.09768058	4054	25.55092011	3855	41.94739	6219	42.60441949	5817	36.2841584	5763	0.010026493	0.681532921	normal	0.487923923	0.499346379	normal	0.143307409	0.571613116	normal	6.83E-05	0.583314671	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000070614(NDST1)-3	--	0.25063	1	0	0	1.18025	4	0	0	0.244071	0	0.954309	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000070669(ASNS)	--	60.84458424	2011	65.49985115	2069	49.27166526	1554	19.50614395	639	16.1340492	490	53.8631101	1724	0	-1.682445809	down	0	-2.096074141	down	0.977972843	0.141351178	normal	0.087800304	-1.000213124	normal	[E]	Amino acid transport and metabolism	Molecular Function: asparagine synthase (glutamine-hydrolyzing) activity (GO:0004066);; Biological Process: asparagine biosynthetic process (GO:0006529);; 	K01953|0|pps:100992820|ASNS; asparagine synthetase (glutamine-hydrolyzing); K01953 asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4] (A)	"Alanine, aspartate and glutamate metabolism (ko00250)"	[E]	Amino acid transport and metabolism	Asparagine synthase;; Glutamine amidotransferase domain;; Glutamine amidotransferase domain;; Glutamine amidotransferases class-II;; Aluminium induced protein	Asparagine synthetase [glutamine-hydrolyzing] GN=ASNS OS=Homo sapiens (Human) PE=1 SV=4	E	Amino acid transport and metabolism	PREDICTED: asparagine synthetase [glutamine-hydrolyzing]-like isoform X1 [Leptonychotes weddellii]
ENSG00000070718(AP3M2)	--	10.51217232	609	12.21478482	683	11.61515126	665	10.05551703	549	8.720441712	468	9.540820751	499	0.955164267	-0.179989782	normal	0.177154179	-0.565281905	normal	0.662236014	-0.421495494	normal	0.040100666	-0.389887782	normal	--	--	--	"K12398|0|ptr:472747|AP3M2; adaptor-related protein complex 3, mu 2 subunit; K12398 AP-3 complex subunit mu (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family;; Clathrin adaptor complex small chain	AP-3 complex subunit mu-2 GN=AP3M2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-3 complex subunit mu-2 [Pantholops hodgsonii]
ENSG00000070729(CNGB1)	--	0.031216666	4	0.023012591	3	0.036692	3	0.046817002	6	0.07094839	6	0.05244049	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K04952|0|pps:100971173|CNGB1; cyclic nucleotide gated channel beta 1; K04952 cyclic nucleotide gated channel beta 1 (A)	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Olfactory transduction (ko04740);; Phototransduction (ko04744)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Cyclic nucleotide-binding domain	Cyclic nucleotide-gated cation channel beta-1 GN=CNGB1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: cyclic nucleotide-gated cation channel beta-1 [Galeopterus variegatus]
ENSG00000070731(ST6GALNAC2)	--	11.46604936	791	10.58557515	727	11.46695458	785	13.73482231	945	13.12447103	901	13.10456725	905	0.946723431	0.225403412	normal	0.909358014	0.2876069	normal	0.956435859	0.196580716	normal	0.224890421	0.235188955	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K06616|0|hsa:10610|ST6GALNAC2, SAITL1, SIAT7, SIAT7B, SIATL1, ST6GalNAII, STHM; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 (EC:2.4.99.7); K06616 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7B) [EC:2.4.99.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 GN=ST6GALNAC2 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 [Galeopterus variegatus]"
ENSG00000070756(PABPC1)	--	659.8369092	25213	703.4027059	25593	623.8819703	23408	853.5687734	30851	771.8847382	28548	903.7529234	32676	0.993338297	0.260302842	normal	0.997495958	0.136206227	normal	0.839774499	0.472912296	normal	0.16851161	0.289915556	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	"K13126|0|ssc:100153958|PABPC1; poly(A) binding protein, cytoplasmic 1; K13126 polyadenylate-binding protein (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; RNA degradation (ko03018)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Poly-adenylate binding protein, unique domain;; Limkain b1;; RNA binding motif"	Polyadenylate-binding protein 1 GN=PABPC1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: polyadenylate-binding protein 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000070759(TESK2)	--	0.107333646	6	0.189139	11	0.197659	9	0.0696507	4	0.296265053	16	0.140245	7	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08842|0|hsa:10420|TESK2; testis-specific kinase 2 (EC:2.7.12.1); K08842 testis-specific kinase 2 [EC:2.7.12.1] (A)	--	--	--	Protein tyrosine kinase;; Protein kinase domain	Dual specificity testis-specific protein kinase 2 GN=TESK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: dual specificity testis-specific protein kinase 2 [Galeopterus variegatus]
ENSG00000070761(CFAP20)	--	32.954714	649	26.26072753	594	26.39364478	598	28.21823174	643	24.9286944	565	25.21691989	575	0.973647228	-0.044127051	normal	0.968651103	-0.093394782	normal	0.971660399	-0.064708075	normal	0.823164267	-0.067803705	normal	--	--	--	--	--	[K]	Transcription	Protein of unknown function (DUF667)	Cilia- and flagella-associated protein 20 GN=CFAP20 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	cilia- and flagella-associated protein 20 [Bos taurus] 
ENSG00000070770(CSNK2A2)	--	31.71251668	1846	30.70344264	1837	29.55804053	1806	30.08183003	1918	35.06262346	2192	31.40027552	1792	0.98614656	0.024348023	normal	0.96263703	0.233293609	normal	0.985790732	-0.019502303	normal	0.721029296	0.083331879	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K03097|0|ptr:454131|CSNK2A2; casein kinase 2, alpha prime polypeptide; K03097 casein kinase II subunit alpha [EC:2.7.11.1] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; NF-kappa B signaling pathway (ko04064);; Wnt signaling pathway (ko04310);; Adherens junction (ko04520);; Tight junction (ko04530);; Measles (ko05162);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[TDK]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Transcription"	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Casein kinase II subunit alpha' GN=CSNK2A2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: casein kinase II subunit alpha' [Orcinus orca] 
ENSG00000070778(PTPN21)	--	4.564046	505	5.0382914	587	5.060530597	597	5.295653	626	5.74055093	658	5.706079379	672	0.909927069	0.278285396	normal	0.963281402	0.142952538	normal	0.960640826	0.162051742	normal	0.404069466	0.190906451	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18025|0|hsa:11099|PTPN21, PTPD1, PTPRL10; protein tyrosine phosphatase, non-receptor type 21 (EC:3.1.3.48); K18025 tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase;; FERM central domain;; FERM N-terminal domain;; FERM C-terminal PH-like domain	Tyrosine-protein phosphatase non-receptor type 21 GN=PTPN21 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 21 [Galeopterus variegatus]
ENSG00000070785(EIF2B3)	--	10.70957062	326	10.99564125	351	11.91418679	373	12.7058325	389	11.400811	342	9.794277483	301	0.93811827	0.223102419	normal	0.966233229	-0.058645275	normal	0.882383615	-0.316273286	normal	0.906965084	-0.046755705	normal	[MJ]	"Cell wall/membrane/envelope biogenesis;; Translation, ribosomal structure and biogenesis"	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K03241|0|ptr:456543|EIF2B3; eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa; K03241 translation initiation factor eIF-2B subunit gamma (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Nucleotidyl transferase;; MobA-like NTP transferase domain;; Bacterial transferase hexapeptide (six repeats)	Translation initiation factor eIF-2B subunit gamma GN=EIF2B3 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: translation initiation factor eIF-2B subunit gamma [Oryctolagus cuniculus] 
ENSG00000070808(CAMK2A)	--	0.085860791	9	0.064041466	5	0.037166674	3	0.08353246	9	0.081227573	8	0.056789187	6	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: calmodulin-dependent protein kinase activity (GO:0004683);; Molecular Function: calmodulin binding (GO:0005516);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04515|0|pon:100172212|CAMK2A; calcium/calmodulin-dependent protein kinase II alpha (EC:2.7.11.17); K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] (A)	ErbB signaling pathway (ko04012);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; HIF-1 signaling pathway (ko04066);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Wnt signaling pathway (ko04310);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; Proteoglycans in cancer (ko05205);; Glioma (ko05214)	[T]	Signal transduction mechanisms	Protein kinase domain;; Calcium/calmodulin dependent protein kinase II Association;; Protein tyrosine kinase;; SnoaL-like domain;; Domain of unknown function (DUF4440)	Calcium/calmodulin-dependent protein kinase type II subunit alpha GN=CAMK2A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [Echinops telfairi] 
ENSG00000070814(TCOF1)	--	27.2035676	3823	25.88525735	3757	30.0476809	4396	31.32946949	4307	26.10944067	3646	22.74453586	3232	0.988353497	0.141092417	normal	0.990676507	-0.064666688	normal	0.644895326	-0.451873594	normal	0.607456448	-0.120388047	normal	--	--	--	K14562|0|pon:100435631|TCOF1; Treacher Collins-Franceschetti syndrome 1; K14562 Treacher Collins syndrome protein (A)	Ribosome biogenesis in eukaryotes (ko03008)	--	--	Treacher Collins syndrome protein Treacle	Treacle protein GN=TCOF1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: treacle protein isoform X1 [Pteropus alecto]
ENSG00000070831(CDC42)	--	83.13663366	2571	87.39180615	2698	79.49433145	2427	136.0114308	4258	125.6980693	3854	106.602318	3310	0.005721324	0.696687415	normal	0.461975925	0.492807428	normal	0.661776142	0.439130458	normal	0.000137191	0.547543029	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K04393|1.37606e-138|xtr:493389|cdc42, Xcdc42, cdc42hs, g25k; cell division cycle 42; K04393 cell division control protein 42 (A)"	MAPK signaling pathway (ko04010);; Endocytosis (ko04144);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Regulation of actin cytoskeleton (ko04810);; GnRH signaling pathway (ko04912);; Salmonella infection (ko05132)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Cell division control protein 42 homolog (Precursor) GN=CDC42 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	cell division control protein 42 homolog [Sus scrofa] 
ENSG00000070882(OSBPL3)	--	5.614954222	575	5.185631864	529	6.087150445	632	8.712711867	946	6.848327545	726	8.373751244	881	0.012033104	0.686003408	normal	0.62875488	0.434211697	normal	0.469909051	0.469969322	normal	0.001534513	0.53516306	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Oxysterol-binding protein;; Pleckstrin homology domain;; PH domain	Oxysterol-binding protein-related protein 3 GN=OSBPL3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 3 [Tupaia chinensis]
ENSG00000070950(RAD18)	--	9.111768685	751	8.207053648	631	9.907746065	724	10.81341249	854	9.087677898	661	6.13267449	516	0.965307783	0.154294749	normal	0.973007976	0.045477216	normal	0.384278073	-0.495677616	normal	0.875330728	-0.074923732	normal	[T]	Signal transduction mechanisms	Molecular Function: metal ion binding (GO:0046872);; 	"K10627|0|hsa:56852|RAD18, RNF73; RAD18 E3 ubiquitin protein ligase; K10627 E3 ubiquitin-protein ligase RAD18 [EC:6.3.2.19] (A)"	--	[L]	"Replication, recombination and repair"	"SAP domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RAD18 GN=RAD18 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: E3 ubiquitin-protein ligase RAD18 isoform X1 [Equus przewalskii]
ENSG00000070961(ATP2B1)	--	46.39877899	4535	51.2821213	5028	44.47327225	4198	37.73607194	3517	36.95260204	3709	40.45192802	3799	0.829030576	-0.3974361	normal	0.651076522	-0.460219094	normal	0.987365712	-0.15231619	normal	0.034331152	-0.341000063	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: calcium-transporting ATPase activity (GO:0005388);; 	"K05850|0|pps:100973331|ATP2B1; ATPase, Ca++ transporting, plasma membrane 1; K05850 Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Salivary secretion (ko04970);; Pancreatic secretion (ko04972)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; Plasma membrane calcium transporter ATPase C terminal;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Cation transporter/ATPase, N-terminus;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase"	Plasma membrane calcium-transporting ATPase 1 GN=ATP2B1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: plasma membrane calcium-transporting ATPase 1 isoform X3 [Tupaia chinensis]
ENSG00000071051(NCK2)	--	18.42052912	706	16.63165196	723	14.98621362	639	10.26715025	434	10.97959574	449	7.726733615	352	0.006129692	-0.730755377	normal	0.012205583	-0.706811934	normal	0.000303165	-0.865729803	normal	6.52E-06	-0.765651913	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K07365|0|ptr:459472|NCK2; NCK adaptor protein 2; K07365 NCK adaptor protein (A)	ErbB signaling pathway (ko04012);; T cell receptor signaling pathway (ko04660)	[T]	Signal transduction mechanisms	Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; SH2 domain;; Bacterial SH3 domain	Cytoplasmic protein NCK2 GN=NCK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cytoplasmic protein NCK2 isoform X1 [Equus caballus] 
ENSG00000071054(MAP4K4)	--	24.6001598	3054	26.01792441	3239	25.64519142	3122	27.1910841	3355	26.41461827	3259	23.72474628	2974	0.988388327	0.104730162	normal	0.9904973	-0.012539837	normal	0.989065877	-0.078318458	normal	0.988833633	0.004708322	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04407|0|mcc:716595|MAP4K4; mitogen-activated protein kinase kinase kinase kinase 4; K04407 mitogen-activated protein kinase kinase kinase kinase 4 [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein kinase domain;; CNH domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase kinase 4 GN=MAP4K4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase kinase 4 isoform X8 [Equus przewalskii]
ENSG00000071073(MGAT4A)	--	2.276152309	202	2.406775516	233	1.827080629	204	1.82951026	154	1.636404051	127	1.8291304	132	0.816702435	-0.418598012	normal	0.00763908	-0.888988604	normal	0.325449091	-0.630466105	normal	0.021938861	-0.651548924	normal	--	--	"Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00738|0|pps:100996009|MGAT4A; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A; K00738 alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145] (A)"	N-Glycan biosynthesis (ko00510)	--	--	N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region	"Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A soluble form GN=MGAT4A OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A [Orycteropus afer afer]"
ENSG00000071082(RPL31)	--	995.9393358	6720	911.200056	6814	934.2290038	6559	714.1189402	5309	754.8653164	4990	694.9578427	4622	0.90743691	-0.370757725	normal	0.650320998	-0.470766058	normal	0.403612066	-0.513108382	normal	0.003860988	-0.451011507	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02910|7.25102e-61|shr:100923948|RPL31; ribosomal protein L31; K02910 large subunit ribosomal protein L31e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L31e	60S ribosomal protein L31 GN=RPL31 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L31 [Monodelphis domestica] 
ENSG00000071127(WDR1)	--	113.856836	6808	117.3467837	7334	119.8798365	7063	128.6109727	7975	119.8183107	7252	109.016622	6704	0.989154732	0.197380031	normal	0.994819804	-0.037640094	normal	0.994095474	-0.083532029	normal	0.928879086	0.026827599	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	WD repeat-containing protein 1 GN=WDR1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: WD repeat-containing protein 1 isoform X2 [Mustela putorius furo] 
ENSG00000071189(SNX13)	--	9.345352103	862	9.205767045	884	10.2895449	830	9.642984217	867	10.20005029	922	10.01937897	927	0.977655733	-0.022448244	normal	0.977277902	0.039228112	normal	0.967401511	0.150906269	normal	0.843804337	0.055287552	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K17925|0|hsa:23161|SNX13, RGS-PX1; sorting nexin 13; K17925 sorting nexin-13 (A)"	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	PXA domain;; Sorting nexin C terminal;; PX domain;; Regulator of G protein signaling domain	Sorting nexin-13 GN=SNX13 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-13 isoform X2 [Orycteropus afer afer]
ENSG00000071205(ARHGAP10)	--	3.44741399	243	4.152606077	293	4.6994556	280	5.05072883	356	4.5494432	316	3.749522098	264	0.452308571	0.517371592	normal	0.963529591	0.087164075	normal	0.963729853	-0.092664824	normal	0.575238441	0.175903488	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K13736|0|hsa:79658|ARHGAP10, GRAF2, PS-GAP, PSGAP; Rho GTPase activating protein 10; K13736 Rho GTPase-activating protein 10 (A)"	Bacterial invasion of epithelial cells (ko05100)	[T]	Signal transduction mechanisms	RhoGAP domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Rho GTPase-activating protein 10 GN=ARHGAP10 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 10 [Ceratotherium simum simum]
ENSG00000071243(ING3)	--	3.515137032	112	2.583414727	99	2.947631251	89	2.569113297	83	2.477356444	80	2.456052669	90	0.872885848	-0.455853449	normal	0.939661833	-0.323349029	normal	0.971943332	0.007698145	normal	0.600835449	-0.267062416	normal	--	--	--	"K11319|0|pps:100986820|ING3; inhibitor of growth family, member 3; K11319 inhibitor of growth protein 3 (A)"	--	[B]	Chromatin structure and dynamics	Inhibitor of growth proteins N-terminal histone-binding;; PHD-finger	Inhibitor of growth protein 3 GN=ING3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: inhibitor of growth protein 3 [Galeopterus variegatus]
ENSG00000071246(VASH1)	--	4.399523	481	3.366258613	404	3.908247002	460	4.3311197	476	5.380316396	598	4.4865944	490	0.970366865	-0.045760645	normal	0.263387217	0.542684109	normal	0.968190654	0.082593322	normal	0.425452468	0.196747505	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of angiogenesis (GO:0045765);; 	--	--	--	--	Vasohibin	Vasohibin-1 GN=VASH1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: vasohibin-1 isoform X1 [Equus caballus]
ENSG00000071282(LMCD1)	--	19.53542925	510	20.41675259	573	18.8434135	513	27.24088422	867	29.1293497	829	17.27947503	506	0.004481523	0.732990628	normal	0.335431358	0.510284912	normal	0.97168709	-0.028029683	normal	0.24334465	0.441641679	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	PET Domain;; LIM domain	LIM and cysteine-rich domains protein 1 GN=LMCD1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LIM and cysteine-rich domains protein 1 isoform X1 [Tupaia chinensis]
ENSG00000071462(WBSCR22)	--	53.30457109	1112	57.34734565	1231	54.093122	1145	52.24210402	1093	54.17505664	1118	55.37541913	1158	0.979550399	-0.055618136	normal	0.969935832	-0.160130607	normal	0.981198397	0.007985725	normal	0.778228833	-0.071152929	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Methyltransferase involved in Williams-Beuren syndrome;; Methyltransferase domain;; Methyltransferase domain	Probable 18S rRNA (guanine-N(7))-methyltransferase GN=WBSCR22 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: uncharacterized methyltransferase WBSCR22 isoform 2 [Equus caballus]
ENSG00000071537(SEL1L)	--	26.6845313	3372	23.88842034	3168	25.37539195	3312	26.73494327	3450	25.72646633	3341	26.22419884	3487	0.991144452	0.00215859	normal	0.989949137	0.055255404	normal	0.990280425	0.065962893	normal	0.884742977	0.039936859	normal	[R]	General function prediction only	--	K14026|0|pps:100976390|SEL1L; sel-1 suppressor of lin-12-like (C. elegans); K14026 SEL1 protein (A)	Protein processing in endoplasmic reticulum (ko04141)	[MOT]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Sel1 repeat;; Fibronectin type II domain	Protein sel-1 homolog 1 (Precursor) GN=SEL1L OS=Homo sapiens (Human) PE=1 SV=3	MOT	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: protein sel-1 homolog 1 [Galeopterus variegatus]
ENSG00000071539(TRIP13)	--	27.39512	1315	27.32940301	1326	29.48922	1377	27.83154464	1320	23.7947274	1127	19.778497	950	0.982451904	-0.025327597	normal	0.940998748	-0.255703084	normal	0.177768908	-0.543098239	normal	0.13134065	-0.264329427	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA domain;; AAA ATPase domain;; AAA domain;; KAP family P-loop domain;; Uncharacterised P-loop hydrolase UPF0079	Pachytene checkpoint protein 2 homolog GN=TRIP13 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: pachytene checkpoint protein 2 homolog [Camelus bactrianus]
ENSG00000071553(ATP6AP1)	--	75.85986471	2614	78.51225056	2726	78.32941235	2721	72.91107371	2491	67.56615271	2307	95.328534	3281	0.986539796	-0.100305978	normal	0.957480906	-0.262035884	normal	0.961653161	0.261574622	normal	0.967979791	-0.017152315	normal	--	--	"Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V1 domain (GO:0033180);; Molecular Function: proton-transporting ATP synthase activity, rotational mechanism (GO:0046933);; Molecular Function: proton-transporting ATPase activity, rotational mechanism (GO:0046961);; "	"K03662|0|hsa:537|ATP6AP1, 16A, ATP6IP1, ATP6S1, Ac45, CF2, VATPS1, XAP-3, XAP3; ATPase, H+ transporting, lysosomal accessory protein 1 (EC:3.6.3.14); K03662 V-type H+-transporting ATPase S1 subunit (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	Vacuolar ATP synthase subunit S1 (ATP6S1)	V-type proton ATPase subunit S1 (Precursor) GN=ATP6AP1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit S1 [Odobenus rosmarus divergens]
ENSG00000071564(TCF3)	--	31.37967855	1749	25.89701003	1464	28.098846	1810	33.89738936	1934	32.047899	1987	25.61268752	1427	0.98208529	0.114129876	normal	0.703392013	0.418877057	normal	0.855693087	-0.350964738	normal	0.845389714	0.068735231	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09063|0|hsa:6929|TCF3, E2A, E47, ITF1, TCF-3, VDIR, bHLHb21; transcription factor 3; K09063 transcription factor E2-alpha (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Transcription factor E2-alpha GN=TCF3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor E2-alpha isoform 2 [Odobenus rosmarus divergens]
ENSG00000071575(TRIB2)	--	0.651894579	22	0.449344659	15	0.13011556	8	1.338942693	53	2.184168896	90	1.402887078	74	0.266815075	1.182931686	normal	8.01E-09	2.450157254	up	1.15E-09	2.981297879	up	1.80E-06	2.248428277	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08814|0|hsa:28951|TRIB2, C5FW, GS3955, TRB2; tribbles pseudokinase 2; K08814 tribbles [EC:2.7.11.-] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Tribbles homolog 2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: tribbles homolog 2 [Loxodonta africana] 
ENSG00000071626(DAZAP1)	--	69.07756	2635	65.97261114	2552	64.992881	2547	77.5437	2999	75.55217	2897	72.10223	2800	0.983318623	0.155761125	normal	0.982079087	0.161414976	normal	0.985194133	0.128263767	normal	0.46117442	0.147716872	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K14411|9.06354e-174|bta:614783|DAZAP1; DAZ associated protein 1; K14411 RNA-binding protein Musashi (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	DAZ-associated protein 1 GN=DAZAP1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: DAZ associated protein 1 [Odobenus rosmarus divergens]
ENSG00000071655(MBD3)	--	73.76960561	2520	76.53069836	2763	71.7577905	2655	87.76738609	2943	85.64942054	2859	90.55158898	3201	0.977926155	0.192922624	normal	0.989285975	0.027833524	normal	0.961111725	0.261383596	normal	0.410505815	0.160662889	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	K11591|0|ptr:455554|MBD3; methyl-CpG binding domain protein 3; K11591 methyl-CpG-binding domain protein 3 (A)	--	[KB]	Transcription;; Chromatin structure and dynamics	C-terminal domain of methyl-CpG binding protein 2 and 3;; Methyl-CpG binding domain	Methyl-CpG-binding domain protein 3 GN=MBD3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: small conductance calcium-activated potassium channel protein 2 [Oryctolagus cuniculus]
ENSG00000071794(HLTF)	--	33.230023	3085	26.7431653	2474	32.222188	2920	23.685906	2212	23.696845	2183	19.033425	1766	0.323377639	-0.510449582	normal	0.973625373	-0.201828486	normal	0.001924767	-0.733280861	normal	0.003098843	-0.482396509	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; Molecular Function: metal ion binding (GO:0046872);; "	"K15711|0|hsa:6596|HLTF, HIP116, HIP116A, HLTF1, RNF80, SMARCA3, SNF2L3, ZBU1; helicase-like transcription factor; K15711 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A3 [EC:3.6.4.- 6.3.2.19] (A)"	--	[KL]	"Transcription;; Replication, recombination and repair"	"SNF2 family N-terminal domain;; HIRAN domain;; Helicase conserved C-terminal domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	Helicase-like transcription factor GN=HLTF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: helicase-like transcription factor isoform X2 [Galeopterus variegatus]
ENSG00000071859(FAM50A)	--	47.22001852	1497	49.84972379	1651	47.13487239	1570	52.48883312	1711	52.85896234	1666	60.76823011	1947	0.974818022	0.161777889	normal	0.984683027	-0.008370645	normal	0.920065347	0.301935242	normal	0.441460166	0.153486054	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K13119|3.85487e-164|hsa:9130|FAM50A, 9F, DXS9928E, HXC-26, HXC26, XAP5; family with sequence similarity 50, member A; K13119 protein FAM50 (A)"	--	[S]	Function unknown	"XAP5, circadian clock regulator"	Protein FAM50A GN=FAM50A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM50A isoform X2 [Mustela putorius furo]
ENSG00000071889(FAM3A)	--	26.4369979	830	23.602958	719	26.87950112	869	24.49735862	714	21.16219349	666	21.25634081	684	0.934126819	-0.247524913	normal	0.966477717	-0.131608441	normal	0.82489131	-0.35295723	normal	0.205721507	-0.24947421	normal	--	--	--	--	--	--	--	--	Protein FAM3A (Precursor) GN=FAM3A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM3A isoform X2 [Oryctolagus cuniculus]
ENSG00000071894(CPSF1)	--	19.80866281	1746	21.30078198	1814	20.8735598	1981	20.83702702	1916	23.40531748	2156	21.77539565	2019	0.982832501	0.103125094	normal	0.964100792	0.227581956	normal	0.986794089	0.019106141	normal	0.589171473	0.11573641	normal	[A]	RNA processing and modification	Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: nucleus (GO:0005634);; 	"K14401|0|hsa:29894|CPSF1, CPSF160, HSU37012, P/cl.18; cleavage and polyadenylation specific factor 1, 160kDa; K14401 cleavage and polyadenylation specificity factor subunit 1 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	CPSF A subunit region;; Mono-functional DNA-alkylating methyl methanesulfonate N-term	Cleavage and polyadenylation specificity factor subunit 1 GN=CPSF1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: cleavage and polyadenylation specificity factor subunit 1 isoform 2 [Ceratotherium simum simum]
ENSG00000071909(MYO3B)	--	0	0	0	0	0	0	0.00941638	1	0.015498377	0	0.028051704	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: myosin complex (GO:0016459);; 	K08834|0|nle:100585760|MYO3B; myosin IIIB; K08834 myosin III [EC:2.7.11.1] (A)	--	[N]	Cell motility	Myosin head (motor domain);; Protein kinase domain;; Protein tyrosine kinase;; IQ calmodulin-binding motif;; Phosphotransferase enzyme family	Myosin-IIIb GN=MYO3B OS=Homo sapiens (Human) PE=2 SV=4	Z	Cytoskeleton	PREDICTED: myosin-IIIb isoform X1 [Galeopterus variegatus]
ENSG00000071967(CYBRD1)	--	35.06620586	2267	37.01021465	2397	33.72391379	2146	31.01008745	2009	28.53350821	1826	34.88851969	2276	0.971494136	-0.204991388	normal	0.736617887	-0.413669661	normal	0.986283155	0.076506682	normal	0.348358684	-0.177266398	normal	--	--	--	K08370|0|pps:100972759|cytochrome b reductase 1; K08370 cytochrome b reductase 1 (A)	Mineral absorption (ko04978)	[C]	Energy production and conversion	Eukaryotic cytochrome b561	Cytochrome b reductase 1 GN=CYBRD1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: cytochrome b reductase 1 [Galeopterus variegatus]
ENSG00000071991(CDH19)	--	0.00991109	1	0.089263131	3	0	0	0.881067341	65	1.281299466	79	0.626642934	47	4.10E-13	4.692137958	up	3.26E-14	4.139646892	up	3.27E-10	4.999534318	up	5.25E-17	5.552563895	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06806|0|pps:100990222|CDH19; cadherin 19, type 2; K06806 cadherin 19, type 2 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin-like	Cadherin-19 (Precursor) GN=CDH19 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: cadherin-19 [Ursus maritimus] 
ENSG00000071994(PDCD2)	--	30.95278776	769	29.64789417	736	30.11205953	733	26.88210464	733	26.40019948	707	26.90968133	714	0.97181142	-0.099798397	normal	0.972495079	-0.079255936	normal	0.974985893	-0.046084227	normal	0.782066727	-0.076506147	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; 	K14801|0|ggo:101126184|PDCD2; programmed cell death protein 2 isoform 1; K14801 pre-rRNA-processing protein TSR4 (A)	--	[R]	General function prediction only	"Programmed cell death protein 2, C-terminal putative domain;; MYND finger"	Programmed cell death protein 2 GN=PDCD2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: programmed cell death protein 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000072041(SLC6A15)	--	10.63213974	486	4.735913882	285	6.665235818	386	20.58277917	944	19.72633425	941	20.91771509	1133	2.21E-05	0.924864317	normal	0	1.696561584	up	5.55E-16	1.541488533	up	2.25E-11	1.362656803	up	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05048|0|pps:100973955|SLC6A15; solute carrier family 6 (neutral amino acid transporter), member 15; K05048 solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium-dependent neutral amino acid transporter B(0)AT2 GN=SLC6A15 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent neutral amino acid transporter B(0)AT2 isoform 1 [Trichechus manatus latirostris]
ENSG00000072042(RDH11)	--	99.94426618	4160	103.4507018	4309	101.6849713	4107	98.74772936	4172	101.9415688	4157	111.0822873	4666	0.992306953	-0.026666799	normal	0.991385532	-0.073210747	normal	0.986201341	0.175749166	normal	0.929516481	0.026355378	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K11152|0|ptr:452986|RDH11; retinol dehydrogenase 11 (all-trans/9-cis/11-cis); K11152 retinol dehydrogenase 11 [EC:1.1.1.300] (A)	Retinol metabolism (ko00830)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; NAD dependent epimerase/dehydratase family;; NADH(P)-binding	Retinol dehydrogenase 11 GN=RDH11 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: retinol dehydrogenase 11 isoform 1 [Odobenus rosmarus divergens]
ENSG00000072062(PRKACA)	--	26.00533089	1182	23.21457727	1051	26.4001999	1220	30.17805286	1229	27.09851124	1149	25.28301652	1082	0.981456422	0.025390251	normal	0.975739691	0.107042232	normal	0.965800833	-0.181233385	normal	0.956592571	-0.018470346	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04345|0|ptr:455776|PRKACA; protein kinase, cAMP-dependent, catalytic, alpha; K04345 protein kinase A [EC:2.7.11.11] (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Vasopressin-regulated water reabsorption (ko04962);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Bile secretion (ko04976);; Parkinson's disease (ko05012);; Prion diseases (ko05020);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Amoebiasis (ko05146);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	cAMP-dependent protein kinase catalytic subunit alpha GN=PRKACA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cAMP-dependent protein kinase catalytic subunit alpha isoform X2 [Condylura cristata]
ENSG00000072071(ADGRL1)	--	4.105294661	537	2.160904673	340	2.258604152	339	2.470729599	317	3.5104276	529	2.053756	264	0.002934344	-0.788299396	normal	0.107817044	0.614100097	normal	0.829210079	-0.367177647	normal	0.855433871	-0.153222255	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: carbohydrate binding (GO:0030246);; 	K04592|0|pps:100967654|LPHN1; latrophilin 1; K04592 latrophilin 1 (A)	--	[T]	Signal transduction mechanisms	Latrophilin Cytoplasmic C-terminal region;; Olfactomedin-like domain;; Domain of unknown function (DUF3497);; 7 transmembrane receptor (Secretin family);; Galactose binding lectin domain;; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain	Latrophilin-1 (Precursor) GN=LPHN1 OS=Homo sapiens (Human) PE=1 SV=1	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: latrophilin-1 isoform X1 [Galeopterus variegatus]
ENSG00000072110(ACTN1)	--	136.0947017	11822	161.8368952	14175	155.836334	13641	163.7331548	14242	142.6440873	12404	150.609404	13138	0.990070025	0.237817178	normal	0.992100101	-0.21394544	normal	0.996795971	-0.062488122	normal	0.965782714	-0.016133423	normal	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	"K05699|0|ssc:100513412|ACTN1; actinin, alpha 1; K05699 actinin alpha (A)"	Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Amoebiasis (ko05146);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Ca2+ insensitive EF hand;; CAMSAP CH domain;; EF hand	Alpha-actinin-1 GN=ACTN1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	Alpha-actinin-1 [Bos mutus]
ENSG00000072121(ZFYVE26)	--	4.11229342	778	5.193996431	1015	4.566432929	862	4.264593008	823	4.051669664	778	6.1807253	1217	0.97591946	0.050193633	normal	0.715636302	-0.40437382	normal	0.381070664	0.48855315	normal	0.908108189	0.065802163	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	FYVE zinc finger	Zinc finger FYVE domain-containing protein 26 GN=ZFYVE26 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger FYVE domain-containing protein 26 [Galeopterus variegatus]
ENSG00000072133(RPS6KA6)	--	3.986545203	375	4.198105002	366	4.136104772	361	4.32886487	393	4.504431334	369	3.701661086	322	0.968770211	0.036659733	normal	0.968167508	-0.009609845	normal	0.952896182	-0.172464155	normal	0.9074175	-0.045569849	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04373|0|pps:100967605|RPS6KA6; ribosomal protein S6 kinase, 90kDa, polypeptide 6; K04373 p90 ribosomal S6 kinase [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; Oocyte meiosis (ko04114);; mTOR signaling pathway (ko04150);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Progesterone-mediated oocyte maturation (ko04914)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family;; Protein kinase C terminal domain;; PhoP regulatory network protein YrbL	Ribosomal protein S6 kinase alpha-6 GN=RPS6KA6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ribosomal protein S6 kinase alpha-6 isoform X2 [Camelus bactrianus]
ENSG00000072134(EPN2)	--	26.41558747	1918	20.86096568	1521	27.14914068	1861	20.51524895	1570	18.058534	1358	11.92998968	950	0.902325061	-0.319387069	normal	0.96870441	-0.18476868	normal	9.91E-07	-0.977237237	normal	0.08272704	-0.473102103	normal	--	--	Molecular Function: phospholipid binding (GO:0005543);; 	K12471|0|ptr:454498|EPN2; epsin 2; K12471 epsin (A)	Endocytosis (ko04144)	[F]	Nucleotide transport and metabolism	ENTH domain;; ANTH domain	Epsin-2 GN=EPN2 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: epsin-2 [Galeopterus variegatus]
ENSG00000072135(PTPN18)	--	7.761897285	593	8.30453344	652	7.826897128	610	5.2035841	402	5.40424372	384	5.516777841	368	0.12389183	-0.589799965	normal	0.002658757	-0.782797256	normal	0.007499913	-0.73502337	normal	6.51E-05	-0.706288128	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	K18024|0|ggo:101136798|PTPN18; tyrosine-protein phosphatase non-receptor type 18 isoform 1; K18024 tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] (A)	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase	Tyrosine-protein phosphatase non-receptor type 18 GN=PTPN18 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 18 isoform X1 [Lipotes vexillifer]
ENSG00000072163(LIMS2)	--	1.297783251	46	1.633247386	59	1.273320277	47	1.425428695	52	1.935318812	68	1.948665402	70	0.97739875	0.141595647	normal	0.969747643	0.179114145	normal	0.891693525	0.5517664	normal	0.631604976	0.301418554	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	LIM and senescent cell antigen-like-containing domain protein 2 GN=LIMS2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LIM and senescent cell antigen-like-containing domain protein 2 isoform X1 [Ochotona princeps]
ENSG00000072182(ASIC4)	--	0.075083619	4	0.072500332	4	0	0	0.018701859	1	0.018286743	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	"K04831|0|cjc:100402717|ASIC4, ACCN4; acid-sensing (proton-gated) ion channel family member 4; K04831 acid-sensing ion channel 4 (A)"	Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Acid-sensing ion channel 4 GN=ASIC4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: acid-sensing ion channel 4 [Tupaia chinensis]
ENSG00000072195(SPEG)	--	5.354991705	407	2.689761153	247	5.3041579	368	2.882834535	210	3.622920708	226	1.666453693	126	8.68E-05	-0.980220748	normal	0.955959474	-0.148662875	normal	4.17E-11	-1.543211363	down	0.02833837	-0.88484025	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08809|0|ptr:743624|SPEG; SPEG complex locus (EC:2.7.11.1); K08809 striated muscle-specific serine/threonine protein kinase [EC:2.7.11.1] (A)	--	--	--	Immunoglobulin I-set domain;; Protein kinase domain;; Immunoglobulin domain;; Protein tyrosine kinase;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Fibronectin type III domain	Striated muscle preferentially expressed protein kinase GN=SPEG OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	striated muscle preferentially expressed protein kinase [Oryctolagus cuniculus] 
ENSG00000072201(LNX1)	--	0.701437	48	0.684606	45	0.60485	39	0.866863	57	0.9759	64	0.560166	37	0.973340013	0.210895175	normal	0.93052904	0.473322694	normal	0.981661479	-0.081014624	normal	0.741081174	0.236911329	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K10692|0|hsa:84708|LNX1, LNX, MPDZ, PDZRN2; ligand of numb-protein X 1, E3 ubiquitin protein ligase (EC:6.3.2.19); K10692 ligand of Numb protein X 1/2 (A)"	--	[S]	Function unknown	"PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Tricorn protease PDZ domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase LNX GN=LNX1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: E3 ubiquitin-protein ligase LNX isoformX2 [Equus caballus] 
ENSG00000072210(ALDH3A2)	--	126.297941	7716	111.9206862	6745	120.144294	7301	73.19398021	4445	75.18432881	4590	67.451655	4177	0.00012114	-0.826282243	normal	0.162736657	-0.576593093	normal	0.000185801	-0.813692585	normal	2.85E-07	-0.741255776	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00128|0|ptr:454505|ALDH3A2; aldehyde dehydrogenase 3 family, member A2; K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Glycerolipid metabolism (ko00561);; Pyruvate metabolism (ko00620)"	[C]	Energy production and conversion	Aldehyde dehydrogenase family;; Acyl-CoA reductase (LuxC)	Fatty aldehyde dehydrogenase GN=ALDH3A2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: fatty aldehyde dehydrogenase [Ochotona princeps]
ENSG00000072274(TFRC)	--	129.6392044	10899	118.4306338	9988	120.260638	9894	150.6725005	12735	116.2610552	9723	131.2398734	11004	0.992803362	0.193745639	normal	0.995755389	-0.060211617	normal	0.99433861	0.145089761	normal	0.691636075	0.098651718	normal	--	--	--	"K06503|0|hsa:7037|TFRC, CD71, T9, TFR, TFR1, TR, TRFR, p90; transferrin receptor; K06503 transferrin receptor (A)"	HIF-1 signaling pathway (ko04066);; Endocytosis (ko04144);; Phagosome (ko04145);; Hematopoietic cell lineage (ko04640)	[OPR]	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism;; General function prediction only"	Transferrin receptor-like dimerisation domain;; Peptidase family M28;; PA domain	"Transferrin receptor protein 1, serum form GN=TFRC OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: transferrin receptor protein 1 [Oryctolagus cuniculus]
ENSG00000072310(SREBF1)	--	54.1537699	3937	60.6578696	4573	44.944382	3510	43.125964	3088	57.504149	4365	70.436788	5138	0.852396654	-0.381087813	normal	0.991318156	-0.088555844	normal	0.240191854	0.541250541	normal	0.938411638	0.046926908	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K07197|0|hsa:6720|SREBF1, SREBP-1c, SREBP1, bHLHd1; sterol regulatory element binding transcription factor 1; K07197 sterol regulatory element-binding transcription factor 1 (A)"	AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Processed sterol regulatory element-binding protein 1 GN=SREBF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: sterol regulatory element-binding protein 1 isoform X2 [Mustela putorius furo]
ENSG00000072315(TRPC5)	--	0.019659	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04968|0|pps:100991195|TRPC5; transient receptor potential cation channel, subfamily C, member 5; K04968 transient receptor potential cation channel subfamily C member 5 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Transient receptor ion channel II;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Short transient receptor potential channel 5 GN=TRPC5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: short transient receptor potential channel 5 [Condylura cristata]
ENSG00000072364(AFF4)	--	24.02896881	3791	26.09540432	4175	25.53324127	3751	25.00750969	4056	26.83552546	4357	28.87374266	4614	0.991291268	0.066620827	normal	0.992051733	0.040118133	normal	0.957975681	0.290345576	normal	0.534023368	0.131985257	normal	--	--	--	"K15185|0|hsa:27125|AFF4, AF5Q31, MCEF; AF4/FMR2 family, member 4; K15185 AF4/FMR2 family member 4 (A)"	--	--	--	AF-4 proto-oncoprotein	AF4/FMR2 family member 4 GN=AFF4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: AF4/FMR2 family member 4 isoform X1 [Lipotes vexillifer] 
ENSG00000072401(UBE2D1)	--	16.398057	532	18.33301	585	18.416967	579	21.592432	710	22.28206	725	22.48196	731	0.759194653	0.384596226	normal	0.905377294	0.287449229	normal	0.862567926	0.327254272	normal	0.082324288	0.331849694	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K06689|3.1224e-106|tgu:100221279|UBE2D1; ubiquitin-conjugating enzyme E2D 1; K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 D1 GN=UBE2D1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 D1 isoform X1 [Monodelphis domestica]
ENSG00000072415(MPP5)	--	15.837999	1267	15.94051296	1344	14.43501916	1252	16.037622	1412	15.64110901	1331	13.62880822	1152	0.976954843	0.125347272	normal	0.982013744	-0.035409088	normal	0.975220379	-0.128223771	normal	0.980476886	-0.009963049	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06091|0|ptr:452978|MPP5; membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5); K06091 MAGUK p55 subfamily member 5 (A)"	Hippo signaling pathway (ko04390);; Tight junction (ko04530)	[T]	Signal transduction mechanisms	Guanylate kinase;; L27_N;; Variant SH3 domain;; PDZ domain (Also known as DHR or GLGF);; PDZ domain;; SH3 domain;; L27 domain	MAGUK p55 subfamily member 5 GN=MPP5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: MAGUK p55 subfamily member 5 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000072422(RHOBTB1)	--	4.901618429	412	4.109243143	351	5.730099404	470	6.184335571	519	7.911931196	666	5.240251357	444	0.890458726	0.301255187	normal	0.000152297	0.899764516	normal	0.967189025	-0.090094218	normal	0.237602752	0.380792852	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07868|0|hsa:9886|RHOBTB1; Rho-related BTB domain containing 1; K07868 Rho-related BTB domain-containing protein 1/2 (A)	Ubiquitin mediated proteolysis (ko04120)	[R]	General function prediction only	BTB/POZ domain;; Ras family;; Miro-like protein	Rho-related BTB domain-containing protein 1 GN=RHOBTB1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rho-related BTB domain-containing protein 1 isoform 1 [Ceratotherium simum simum] 
ENSG00000072501(SMC1A)	--	113.8564186	6747	117.004636	6986	122.9299397	7421	122.6880669	6949	117.5538714	6612	112.7714734	6666	0.994894241	0.011724325	normal	0.993455424	-0.100784046	normal	0.991258953	-0.163048655	normal	0.727756269	-0.085841763	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: chromosome (GO:0005694);; Biological Process: chromosome organization (GO:0051276);; 	K06636|0|ngi:103747317|Smc1a; structural maintenance of chromosomes 1A; K06636 structural maintenance of chromosome 1 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114)	[D]	"Cell cycle control, cell division, chromosome partitioning"	RecF/RecN/SMC N terminal domain;; SMC proteins Flexible Hinge Domain;; AAA domain;; P-loop containing region of AAA domain	Structural maintenance of chromosomes protein 1A GN=SMC1A OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: structural maintenance of chromosomes protein 1A [Ailuropoda melanoleuca] 
ENSG00000072518(MARK2)	--	11.69751257	1003	11.09657041	922	10.51321893	915	14.05321484	1119	12.32012077	1097	14.07705287	1042	0.973525623	0.126872114	normal	0.948553766	0.228953679	normal	0.963529101	0.178942867	normal	0.381492324	0.176630172	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08798|0|hsa:2011|MARK2, EMK-1, EMK1, PAR-1, Par-1b, Par1b; MAP/microtubule affinity-regulating kinase 2 (EC:2.7.11.1 2.7.11.26); K08798 MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase associated domain 1;; Kinase-like;; RIO1 family	Serine/threonine-protein kinase MARK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase MARK2 [Camelus ferus]
ENSG00000072571(HMMR)	--	21.04824349	1321	15.61232772	969	20.78109742	1269	17.86784219	1127	16.62290319	1050	14.69121912	895	0.93808586	-0.259647829	normal	0.975693657	0.094252868	normal	0.287802346	-0.51129458	normal	0.362667182	-0.233902401	normal	--	--	--	"K06267|0|hsa:3161|HMMR, CD168, IHABP, RHAMM; hyaluronan-mediated motility receptor (RHAMM); K06267 hyaluronan-mediated motility receptor (A)"	ECM-receptor interaction (ko04512)	--	--	--	Hyaluronan mediated motility receptor GN=HMMR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: hyaluronan mediated motility receptor [Odobenus rosmarus divergens]
ENSG00000072609(CHFR)	--	12.47992309	1012	13.71161156	1163	11.17916303	946	15.6672796	1234	16.55472366	1273	15.7741661	1274	0.938432624	0.254949868	normal	0.976946401	0.108819486	normal	0.657265383	0.420580329	normal	0.150357672	0.255405547	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K10644|0|hsa:55743|CHFR, RNF116, RNF196; checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase; K10644 E3 ubiquitin-protein ligase CHFR [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"FHA domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase CHFR GN=CHFR OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase CHFR isoform X1 [Galeopterus variegatus]
ENSG00000072657(TRHDE)	--	0.00682181	1	0.007278558	1	0.014639321	1	0.3893874	19	0.536679996	24	0.195900424	11	--	--	--	0.002757646	3.329789018	up	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	"K01306|0|hsa:29953|TRHDE, PAP-II, PGPEP2, TRH-DE; thyrotropin-releasing hormone degrading enzyme (EC:3.4.19.6); K01306 pyroglutamyl-peptidase II [EC:3.4.19.6] (A)"	--	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	Thyrotropin-releasing hormone-degrading ectoenzyme GN=TRHDE OS=Homo sapiens (Human) PE=2 SV=1	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: thyrotropin-releasing hormone-degrading ectoenzyme [Mustela putorius furo] 
ENSG00000072682(P4HA2)	--	34.85250445	1630	28.84863244	1395	32.64720795	1549	48.86469508	2224	38.13312182	1742	35.11941576	1643	0.702380902	0.4171148	normal	0.920211343	0.298762599	normal	0.982891927	0.076631242	normal	0.230154175	0.272177013	normal	--	--	"Molecular Function: procollagen-proline 4-dioxygenase activity (GO:0004656);; Cellular Component: endoplasmic reticulum (GO:0005783);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00472|0|ptr:462047|P4HA2; prolyl 4-hydroxylase, alpha polypeptide II; K00472 prolyl 4-hydroxylase [EC:1.14.11.2] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	"Prolyl 4-Hydroxylase alpha-subunit, N-terminal region;; 2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily"	Prolyl 4-hydroxylase subunit alpha-2 (Precursor) GN=P4HA2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: prolyl 4-hydroxylase subunit alpha-2 isoform X1 [Galeopterus variegatus] 
ENSG00000072736(NFATC3)	--	9.2256668	945	9.404912444	948	8.84257255	897	9.286576554	971	8.595777817	918	8.330295	830	0.97902348	0.008311372	normal	0.976474875	-0.067709692	normal	0.971589959	-0.120077575	normal	0.831332301	-0.058935286	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K17333|0|ptr:454184|NFATC3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3; K17333 nuclear factor of activated T-cells, cytoplasmic 3 (A)"	MAPK signaling pathway (ko04010);; cGMP-PKG signaling pathway (ko04022);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Oxytocin signaling pathway (ko04921);; Hepatitis B (ko05161);; HTLV-I infection (ko05166)	--	--	Rel homology domain (RHD);; IPT/TIG domain	"Nuclear factor of activated T-cells, cytoplasmic 3 GN=NFATC3 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: nuclear factor of activated T-cells, cytoplasmic 3 isoform X1 [Ailuropoda melanoleuca] "
ENSG00000072756(TRNT1)	--	22.395517	679	21.9528	684	25.239418	772	18.349414	579	19.748499	601	20.035922	607	0.92352802	-0.260042432	normal	0.94814026	-0.207567896	normal	0.821187826	-0.354410848	normal	0.163947142	-0.277504578	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K00974|0|hsa:51095|TRNT1, CCA1, MtCCA, SIFD; tRNA nucleotidyl transferase, CCA-adding, 1 (EC:2.7.7.72); K00974 tRNA nucleotidyltransferase (CCA-adding enzyme) [EC:2.7.7.72 3.1.3.- 3.1.4.-] (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Poly A polymerase head domain;; Probable RNA and SrmB- binding site of polymerase A	"CCA tRNA nucleotidyltransferase 1, mitochondrial (Precursor) GN=TRNT1 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: CCA tRNA nucleotidyltransferase 1, mitochondrial [Ceratotherium simum simum]"
ENSG00000072778(ACADVL)	--	143.0627361	6135	114.3213127	4926	128.6838013	5697	145.9648385	6419	143.3398116	6200	117.6931445	5113	0.994396625	0.03444452	normal	0.957461678	0.310339945	normal	0.989148823	-0.164277766	normal	0.823164267	0.059780756	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K09479|0|hsa:37|ACADVL, ACAD6, LCACD, VLCAD; acyl-CoA dehydrogenase, very long chain (EC:1.3.8.9); K09479 very long chain acyl-CoA dehydrogenase [EC:1.3.8.9] (A)"	Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	"Very long-chain specific acyl-CoA dehydrogenase, mitochondrial (Precursor) GN=ACADVL OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: very long-chain specific acyl-CoA dehydrogenase, mitochondrial [Myotis brandtii]"
ENSG00000072786(STK10)	--	7.049620499	979	5.498853819	776	7.604938288	1020	8.727302487	1213	8.098752924	1090	5.924316893	824	0.923147306	0.277974007	normal	0.489756429	0.468000112	normal	0.883354794	-0.315622673	normal	0.674789029	0.150322063	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08837|0|hsa:6793|STK10, LOK, PRO2729; serine/threonine kinase 10 (EC:2.7.11.1); K08837 serine/threonine kinase 10 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Polo kinase kinase;; Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 10 GN=STK10 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 10 [Odobenus rosmarus divergens]
ENSG00000072803(FBXW11)	--	27.63527117	1746	29.82152983	1918	28.12025407	1826	27.572549	1822	27.07475636	1735	27.85740151	1773	0.985530799	0.030610768	normal	0.975963592	-0.165955964	normal	0.985175718	-0.05074302	normal	0.79658904	-0.063982562	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: protein dimerization activity (GO:0046983);; 	K03362|0|lve:103072434|FBXW11; F-box and WD repeat domain containing 11; K03362 F-box and WD-40 domain protein 1/11 (A)	Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Circadian rhythm (ko04710)	[S]	Function unknown	"WD domain, G-beta repeat;; D domain of beta-TrCP;; F-box-like;; F-box domain;; Nup133 N terminal like"	F-box/WD repeat-containing protein 11 GN=FBXW11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/WD repeat-containing protein 11 isoform X1 [Ochotona princeps]
ENSG00000072818(ACAP1)	--	7.410746313	12	13.02520343	11	4.468924355	4	2.847722921	4	1.29937	3	1.703078703	2	--	--	--	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; 	"K12489|0|pps:100983146|ACAP1; ArfGAP with coiled-coil, ankyrin repeat and PH domains 1; K12489 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; PH domain;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 GN=ACAP1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 [Tupaia chinensis]"
ENSG00000072832(CRMP1)	--	9.4934609	558	9.29233	551	8.300299	494	2.218268	130	3.23731	190	2.04303	120	0	-2.1193791	down	5.64E-13	-1.549882218	down	0	-2.036045809	down	4.23E-23	-1.886571191	down	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[F]	Nucleotide transport and metabolism	Amidohydrolase family;; Amidohydrolase;; Amidohydrolase	Dihydropyrimidinase-related protein 1 GN=CRMP1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: dihydropyrimidinase-related protein 1 isoform X2 [Mustela putorius furo]
ENSG00000072840(EVC)	--	4.13151591	871	4.320301456	997	5.2592009	1088	5.181002	1150	5.035599639	1132	4.386438283	980	0.797584591	0.369488211	normal	0.968074906	0.161551904	normal	0.968513519	-0.158883533	normal	0.589772795	0.120731708	normal	--	--	--	--	--	--	--	--	Ellis-van Creveld syndrome protein GN=EVC OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ellis-van Creveld syndrome protein [Ceratotherium simum simum]
ENSG00000072849(DERL2)	--	28.32862036	838	28.39537202	911	28.266051	711	41.84764858	1030	33.55284656	955	38.03114068	1096	0.927025503	0.266348833	normal	0.977430503	0.046547651	normal	0.049982977	0.614973361	normal	0.085373003	0.303324348	normal	[S]	Function unknown	--	K13989|1.05093e-149|pps:100975730|DERL2; derlin 2; K13989 Derlin-2/3 (A)	Protein processing in endoplasmic reticulum (ko04141)	[S]	Function unknown	Der1-like family	Derlin-2 GN=DERL2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: derlin-2 [Eptesicus fuscus]
ENSG00000072858(SIDT1)	--	0.255899305	22	0.346760578	29	0.18894909	16	0.904922096	80	1.598634191	142	1.346068421	119	0.000102729	1.763011996	up	5.06E-11	2.212929322	up	2.66E-13	2.774859356	up	1.45E-06	2.326761308	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: dsRNA transport (GO:0033227);; Molecular Function: RNA transmembrane transporter activity (GO:0051033);; 	--	--	--	--	dsRNA-gated channel SID-1	SID1 transmembrane family member 1 (Precursor) GN=SIDT1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: SID1 transmembrane family member 1 isoform 10 [Dasypus novemcinctus]
ENSG00000072864(NDE1)	--	10.26322997	675	9.613335707	658	11.9945282	716	12.83203303	825	10.49200648	684	13.09744863	740	0.927531792	0.25814217	normal	0.973837687	0.034404628	normal	0.975304002	0.039192812	normal	0.652212058	0.11290214	normal	--	--	--	"K16738|0|hsa:54820|NDE1, HOM-TES-87, LIS4, MHAC, NDE, NUDE, NUDE1; nudE neurodevelopment protein 1; K16738 nuclear distribution protein NudE (A)"	--	[Z]	Cytoskeleton	"NUDE protein, C-terminal conserved region"	Nuclear distribution protein nudE homolog 1 GN=NDE1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	nuclear distribution protein nudE homolog 1 [Canis lupus familiaris]
ENSG00000072952(MRVI1)	--	0	0	0.016772745	2	0.03479308	1	0	0	0.015967814	0	0.017992446	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K12337|0|pps:100987349|MRVI1; murine retrovirus integration site 1 homolog; K12337 inositol 1,4,5-triphosphate receptor-associated cGMP kinase substrate (A)"	cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270)	--	--	MRVI1 protein	Protein MRVI1 GN=MRVI1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein MRVI1 isoform 1 [Ceratotherium simum simum]
ENSG00000072954(TMEM38A)	--	1.79367763	66	1.562693065	64	1.795404012	53	1.039175	37	1.928606104	55	1.165669202	39	0.607441572	-0.839309204	normal	0.967194753	-0.234093505	normal	0.953498524	-0.436243582	normal	0.366079871	-0.503472867	normal	--	--	Molecular Function: cation channel activity (GO:0005261);; Biological Process: monovalent inorganic cation transport (GO:0015672);; Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	TRIC channel	Trimeric intracellular cation channel type A GN=TMEM38A OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: trimeric intracellular cation channel type A [Lipotes vexillifer]
ENSG00000072958(AP1M1)	--	28.23177126	1074	26.69057897	1031	26.67934973	1034	31.03650775	1202	29.83376621	1149	31.27500305	1188	0.973961776	0.131432851	normal	0.972565087	0.134720656	normal	0.962640113	0.191745385	normal	0.468246626	0.151773477	normal	--	--	--	"K12393|0|mcf:102141131|AP1M1; adaptor-related protein complex 1, mu 1 subunit; K12393 AP-1 complex subunit mu (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family;; Clathrin adaptor complex small chain	AP-1 complex subunit mu-1 GN=AP1M1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-1 complex subunit mu-1 isoform 1 [Trichechus manatus latirostris] 
ENSG00000073008(PVR)	--	48.5275203	3932	44.808908	3751	52.1420232	4143	70.78874432	6026	73.485792	5853	66.94332002	5561	0.110640332	0.584919202	normal	0.059275566	0.620272722	normal	0.800034827	0.416245475	normal	0.000272472	0.539160477	normal	--	--	--	K06539|0|pps:100969523|PVR; poliovirus receptor; K06539 poliovirus receptor (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain	Poliovirus receptor (Precursor) GN=PVR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: poliovirus receptor [Tursiops truncatus]
ENSG00000073050(XRCC1)	--	18.493706	1224	18.76794766	1335	18.33461054	1340	18.69485331	1389	19.59535825	1391	17.63110166	1477	0.973255688	0.151432261	normal	0.982163719	0.037814155	normal	0.976976917	0.132003436	normal	0.637294429	0.105788498	normal	--	--	Biological Process: single strand break repair (GO:0000012);; Molecular Function: damaged DNA binding (GO:0003684);; Cellular Component: nucleus (GO:0005634);; 	"K10803|0|hsa:7515|XRCC1, RCC; X-ray repair complementing defective repair in Chinese hamster cells 1; K10803 DNA-repair protein XRCC1 (A)"	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	XRCC1 N terminal domain;; BRCA1 C Terminus (BRCT) domain;; twin BRCT domain	DNA repair protein XRCC1 GN=XRCC1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein XRCC1 [Tupaia chinensis]
ENSG00000073060(SCARB1)	--	129.7961858	5389	124.9121293	4994	121.3437784	4803	143.2716137	5959	128.4545626	5457	136.7021314	5684	0.992210788	0.11418943	normal	0.991745729	0.10645482	normal	0.980196266	0.234611325	normal	0.473592902	0.149769623	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K13885|0|pps:100985228|SCARB1; scavenger receptor class B, member 1; K13885 scavenger receptor class B, member 1 (A)"	Phagosome (ko04145);; Ovarian steroidogenesis (ko04913);; Fat digestion and absorption (ko04975);; Bile secretion (ko04976);; Vitamin digestion and absorption (ko04977);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	CD36 family	Scavenger receptor class B member 1 GN=SCARB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: scavenger receptor class B member 1 [Tupaia chinensis]
ENSG00000073067(CYP2W1)	--	0.174779163	7	0.098540385	4	0.213988292	8	0.125177875	5	0.072653038	2	0.220894902	9	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07423|0|hsa:54905|CYP2W1; cytochrome P450, family 2, subfamily W, polypeptide 1; K07423 cytochrome P450, family 2, subfamily W, polypeptide 1 (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2W1 GN=CYP2W1 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2W1 [Galeopterus variegatus]
ENSG00000073111(MCM2)	--	36.28050956	2734	36.6593928	2816	39.71075152	3002	33.7095	2545	35.5546	2666	32.457568	2445	0.984607695	-0.134101714	normal	0.986924857	-0.10034172	normal	0.935166121	-0.304210829	normal	0.337350375	-0.1808055	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA helicase activity (GO:0003678);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication initiation (GO:0006270);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: MCM complex (GO:0042555);; 	"K02540|0|ptr:460668|MCM2, MCM7; minichromosome maintenance complex component 2; K02540 DNA replication licensing factor MCM2 [EC:3.6.4.12] (A)"	DNA replication (ko03030);; Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; Mini-chromosome maintenance protein 2;; MCM N-terminal domain;; Magnesium chelatase, subunit ChlI;; ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily)"	DNA replication licensing factor MCM2 GN=MCM2 OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: DNA replication licensing factor MCM2 [Ochotona princeps]
ENSG00000073146(MOV10L1)	--	0	0	0.088797938	2	0	0	0	0	0.012698812	0	0.049092582	2	--	--	--	--	--	--	--	--	--	--	--	--	[L]	"Replication, recombination and repair"	--	K13983|0|pps:100974955|MOV10L1; Mov10 RISC complex RNA helicase like 1; K13983 putative helicase MOV10L1 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	AAA domain;; AAA domain;; S1-like;; AAA domain;; Part of AAA domain	Putative helicase Mov10l1 GN=MOV10L1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: putative helicase Mov10l1 isoform X1 [Felis catus]
ENSG00000073150(PANX2)	--	3.246439999	190	3.596283887	210	2.502465406	154	3.303698681	195	4.023316843	238	4.244636171	251	0.967043407	0.006589842	normal	0.954648955	0.158075875	normal	0.117342107	0.691098714	normal	0.388731016	0.283240348	normal	--	--	Cellular Component: gap junction (GO:0005921);; 	K03443|0|mcf:101865728|uncharacterized LOC101865728; K03443 pannexin (A)	--	--	--	Innexin	Pannexin-2 GN=PANX2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: pannexin-2 [Odobenus rosmarus divergens]
ENSG00000073169(SELENOO)	--	12.43072	480	14.115818	565	12.936	524	11.86938	465	12.59902	489	15.44423	603	0.968499775	-0.076387509	normal	0.937315869	-0.2291829	normal	0.951236508	0.193778026	normal	0.929003287	-0.031520861	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	"Uncharacterized ACR, YdiU/UPF0061 family"	Selenoprotein O GN=SELO OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: selenoprotein O-like [Odobenus rosmarus divergens]
ENSG00000073282(TP63)	--	0.497832442	33	0.102912613	9	0.455139438	23	1.900732319	129	3.96365933	311	1.365106462	112	4.88E-08	1.888295244	up	0	4.873931304	up	3.30E-09	2.203290977	up	0.014427624	3.065602772	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: transcription regulatory region DNA binding (GO:0044212);; Biological Process: protein tetramerization (GO:0051262);; 	K10149|0|mcf:102137688|TP63; tumor protein p63; K10149 tumor protein p63 (A)	MicroRNAs in cancer (ko05206)	--	--	P53 DNA-binding domain;; P53 tetramerisation motif;; SAM domain (Sterile alpha motif)	Tumor protein 63 GN=TP63 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: tumor protein 63 isoform 1 [Ovis aries] 
ENSG00000073331(ALPK1)	--	4.02894724	421	3.1761216	347	3.761232398	393	2.438618791	243	2.61563762	269	3.581495693	372	0.002902555	-0.819705551	normal	0.798391349	-0.386835572	normal	0.965935602	-0.087173296	normal	0.118943386	-0.413080443	normal	--	--	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08868|0|hsa:80216|ALPK1, 8430410J10Rik, LAK; alpha-kinase 1; K08868 alpha-kinase (A)"	--	--	--	Alpha-kinase family	Alpha-protein kinase 1 GN=ALPK1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: alpha-protein kinase 1 [Galeopterus variegatus]
ENSG00000073350(LLGL2)	--	16.07333042	1195	11.97200701	1080	14.16839981	1110	14.80234959	1126	18.30025372	1534	20.8357924	1886	0.975952818	-0.116481733	normal	0.424393983	0.484268973	normal	0.00116037	0.755679659	normal	0.2684531	0.405775898	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06094|0|pps:100991928|LLGL2; lethal giant larvae homolog 2 (Drosophila); K06094 lethal(2) giant larvae protein (A)	Hippo signaling pathway (ko04390);; Tight junction (ko04530)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"LLGL2;; WD domain, G-beta repeat"	Lethal(2) giant larvae protein homolog 2 GN=LLGL2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: lethal(2) giant larvae protein homolog 2 isoform X1 [Galeopterus variegatus]
ENSG00000073417(PDE8A)	--	44.57406794	3457	44.32185	3362	43.27150149	3279	28.37992	2142	28.280683	2174	36.229191	2799	0.002693194	-0.720983069	normal	0.023302939	-0.650027657	normal	0.970268751	-0.236517659	normal	0.000260889	-0.525597939	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K18437|0|ptr:453612|PDE8A; phosphodiesterase 8A; K18437 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; Response regulator receiver domain;; PAS fold;; PAS domain;; PAS fold	"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A GN=PDE8A OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A isoform X2 [Oryctolagus cuniculus]"
ENSG00000073464(CLCN4)	--	3.36059417	363	4.091951469	430	3.364204023	388	2.672473033	285	2.5589781	271	3.314137714	383	0.806434402	-0.378028998	normal	0.044247704	-0.684409916	normal	0.969183061	-0.026898179	normal	0.13799735	-0.351214579	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05012|0|ptr:473516|CLCN4; chloride channel, voltage-sensitive 4; K05012 chloride channel 3/4/5 (A)"	--	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	H(+)/Cl(-) exchange transporter 4 GN=CLCN4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: H(+)/Cl(-) exchange transporter 4 isoform X3 [Equus caballus] 
ENSG00000073536(NLE1)	--	13.07355207	863	11.61655095	784	14.86743091	950	16.81781066	1020	15.08784067	1024	13.63601805	906	0.954004655	0.209960299	normal	0.814015873	0.363248894	normal	0.97642586	-0.076583055	normal	0.442962457	0.162641673	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14855|0|pon:100171489|NLE1; notchless homolog 1 (Drosophila); K14855 ribosome assembly protein 4 (A)	--	[S]	Function unknown	"WD domain, G-beta repeat;; NLE (NUC135) domain;; Eukaryotic translation initiation factor eIF2A;; Nucleoporin Nup120/160;; Nup133 N terminal like;; WD40-like Beta Propeller Repeat"	Notchless protein homolog 1 GN=NLE1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: notchless protein homolog 1 isoform X1 [Myotis lucifugus]
ENSG00000073578(SDHA)	--	61.6816309	2838	55.17018659	2621	58.32385104	2759	57.71345019	2664	59.32409769	2712	60.55796964	2760	0.985953689	-0.122044556	normal	0.988863871	0.0277975	normal	0.989586754	-0.007764377	normal	0.896736187	-0.035508165	normal	[C]	Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00234|0|pon:100173631|SDHA; succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (EC:1.3.5.1); K00234 succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:1.3.5.1] (A)"	Citrate cycle (TCA cycle) (ko00020);; Oxidative phosphorylation (ko00190);; Carbon metabolism (ko01200);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	FAD binding domain;; Fumarate reductase flavoprotein C-term;; Pyridine nucleotide-disulphide oxidoreductase;; Thi4 family;; Glucose inhibited division protein A	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (Precursor) GN=SDHA OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial isoform 1 [Canis lupus familiaris]"
ENSG00000073584(SMARCE1)	--	65.343977	2560	59.851444	2558	58.279556	2621	66.10142733	2950	65.30180582	3097	58.3236241	2474	0.980936893	0.173641743	normal	0.963345682	0.254291758	normal	0.986961736	-0.091508941	normal	0.580166073	0.117289527	normal	--	--	--	"K11651|0|nle:100586570|SMARCE1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1; K11651 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E, member 1 (A)"	--	[B]	Chromatin structure and dynamics	HMG (high mobility group) box;; HMG-box domain	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 GN=SMARCE1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 isoform X2 [Elephantulus edwardii]
ENSG00000073598(FNDC8)	--	0	0	0	0	0.0787255	1	0	0	0.0393305	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain	Fibronectin type III domain-containing protein 8 GN=FNDC8 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: fibronectin type III domain-containing protein 8 [Mustela putorius furo] 
ENSG00000073605(GSDMB)	--	28.59111849	1254	25.02469481	1146	27.90998328	1267	29.6729689	1286	34.0220182	1455	25.65769162	1159	0.982246682	0.005514359	normal	0.889406377	0.322606954	normal	0.974314174	-0.136656793	normal	0.788563773	0.067596428	normal	--	--	--	--	--	--	--	Gasdermin family	Gasdermin-B GN=GSDMB OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: gasdermin-B [Equus przewalskii]
ENSG00000073614(KDM5A)	--	10.9252068	2214	11.04067508	2282	10.016533	2167	12.17956288	2541	12.00334911	2560	12.09025535	2472	0.97971196	0.167800135	normal	0.982413599	0.144328121	normal	0.977352671	0.181569432	normal	0.397698873	0.163363801	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K11446|0|hsa:5927|KDM5A, RBBP-2, RBBP2, RBP2, JARID1A; lysine (K)-specific demethylase 5A; K11446 histone demethylase JARID1 [EC:1.14.11.-] (A)"	--	[R]	General function prediction only	"PLU-1-like protein;; JmjC domain, hydroxylase;; PHD-finger;; ARID/BRIGHT DNA binding domain;; C5HC2 zinc finger;; jmjN domain"	Lysine-specific demethylase 5A GN=KDM5A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: lysine-specific demethylase 5A [Odobenus rosmarus divergens]
ENSG00000073670(ADAM11)	--	2.2395155	228	1.844119496	192	1.86272068	196	0.86021126	88	0.760587569	78	0.578099421	60	3.84E-07	-1.388640511	down	1.34E-05	-1.304314506	down	3.59E-09	-1.691153638	down	1.57E-07	-1.468987048	down	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K16067|0|hsa:4185|ADAM11, MDC; ADAM metallopeptidase domain 11; K16067 disintegrin and metalloproteinase domain-containing protein 11 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; ADAM cysteine-rich;; Disintegrin;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12	Disintegrin and metalloproteinase domain-containing protein 11 (Precursor) GN=ADAM11 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 11 [Oryctolagus cuniculus]
ENSG00000073711(PPP2R3A)	--	2.638824005	313	2.195367462	256	2.78047695	291	2.823094	350	3.04754105	336	2.392871526	246	0.960209701	0.129757477	normal	0.82886509	0.368983108	normal	0.929789242	-0.249241759	normal	0.794776162	0.093928716	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K11583|0|pps:100980790|PPP2R3A; protein phosphatase 2, regulatory subunit B'', alpha; K11583 serine/threonine-protein phosphatase 2A regulatory subunit B'' (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Dopaminergic synapse (ko04728)	[A]	RNA processing and modification	EF-hand domain pair;; EF hand;; EF-hand domain	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha GN=PPP2R3A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000073712(FERMT2)	--	11.08883342	685	13.30794323	820	13.52448846	799	21.85234416	1360	19.83377445	1225	17.09308821	1058	3.55E-06	0.957046984	normal	0.161282789	0.556813999	normal	0.729895217	0.396127173	normal	3.86E-05	0.639119636	normal	--	--	--	"K17083|0|hsa:10979|FERMT2, KIND2, MIG2, PLEKHC1, UNC112, UNC112B, mig-2; fermitin family member 2; K17083 kindlin 2 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	FERM central domain;; PH domain;; FERM N-terminal domain	Fermitin family homolog 2 GN=FERMT2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: fermitin family homolog 2 isoform X3 [Bubalus bubalis]
ENSG00000073734(ABCB11)	--	0	0	0	0	0	0	0	0	0	0	0.010645	1	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05664|0|hsa:8647|ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP; ATP-binding cassette, sub-family B (MDR/TAP), member 11; K05664 ATP-binding cassette, subfamily B (MDR/TAP), member 11 (A)"	ABC transporters (ko02010);; Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"ABC transporter transmembrane region;; ABC transporter;; RecF/RecN/SMC N terminal domain;; AAA domain;; Protein of unknown function, DUF258;; AAA domain;; P-loop containing region of AAA domain;; Predicted ATPase of the ABC class"	Bile salt export pump GN=ABCB11 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: bile salt export pump [Mustela putorius furo] 
ENSG00000073737(DHRS9)	--	1.963572934	53	1.648269827	37	2.36139666	51	1.333786077	34	1.452650071	39	1.047195834	27	0.893833434	-0.647652329	normal	0.980953959	0.052434763	normal	0.717414506	-0.889023403	normal	0.405782536	-0.517094628	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K11149|0|pon:100454498|DHRS9; dehydrogenase/reductase (SDR family) member 9; K11149 dehydrogenase/reductase SDR family member 9 [EC:1.1.-.-] (A)	Retinol metabolism (ko00830)	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase	Dehydrogenase/reductase SDR family member 9 (Precursor) GN=DHRS9 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 9 [Leptonychotes weddellii]
ENSG00000073754(CD5L)	--	0	0	0	0	0	0	0	0	0	0	0.0505898	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	CD5 antigen-like (Precursor) GN=CD5L OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CD5 antigen-like [Oryctolagus cuniculus]
ENSG00000073756(PTGS2)	--	40.8045	2630	54.9584	3498	26.7992	1683	20.4733	1331	34.1269	2199	73.4249	4745	1.65E-07	-1.012535853	down	0.008271312	-0.690729011	normal	0	1.486250466	up	0.971576238	0.064674543	normal	--	--	--	"K11987|0|hsa:5743|PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2; prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1); K11987 prostaglandin-endoperoxide synthase 2 [EC:1.14.99.1] (A)"	Arachidonic acid metabolism (ko00590);; NF-kappa B signaling pathway (ko04064);; VEGF signaling pathway (ko04370);; TNF signaling pathway (ko04668);; Retrograde endocannabinoid signaling (ko04723);; Serotonergic synapse (ko04726);; Ovarian steroidogenesis (ko04913);; Oxytocin signaling pathway (ko04921);; Leishmaniasis (ko05140);; Pathways in cancer (ko05200);; Chemical carcinogenesis (ko05204);; MicroRNAs in cancer (ko05206);; Small cell lung cancer (ko05222)	[R]	General function prediction only	Animal haem peroxidase	Prostaglandin G/H synthase 2 (Precursor) GN=PTGS2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	hypothetical protein PANDA_014299 [Ailuropoda melanoleuca]
ENSG00000073792(IGF2BP2)	--	10.6448765	846	9.299232097	683	10.61295234	826	12.79973553	1019	13.80013099	1097	10.36304904	812	0.943061211	0.237199274	normal	0.022191562	0.66101452	normal	0.976873825	-0.032892756	normal	0.198867697	0.292632123	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	K17392|0|ptr:460903|IGF2BP2; insulin-like growth factor 2 mRNA binding protein 2; K17392 insulin-like growth factor 2 mRNA-binding protein 2 (A)	--	[AR]	RNA processing and modification;; General function prediction only	"KH domain;; KH domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; KH domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; KH domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Insulin-like growth factor 2 mRNA-binding protein 2 GN=IGF2BP2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: insulin-like growth factor 2 mRNA-binding protein 2 isoform 1 [Orcinus orca]
ENSG00000073803(MAP3K13)	--	10.01844669	305	9.818579327	279	11.12207183	277	9.967908071	351	9.708078032	313	11.32349686	394	0.952951132	0.171025971	normal	0.956788373	0.143735124	normal	0.48910248	0.497728456	normal	0.300600362	0.276283955	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04422|0|ptr:737524|MAP3K13; mitogen-activated protein kinase kinase kinase 13; K04422 mitogen-activated protein kinase kinase kinase 13 [EC:2.7.11.25] (A)	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Mitogen-activated protein kinase kinase kinase 13 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 13 [Ailuropoda melanoleuca] 
ENSG00000073849(ST6GAL1)	--	2.487476124	212	2.877578306	156	2.194560107	180	2.712160163	228	2.512507118	188	3.103802779	267	0.964840344	0.073622748	normal	0.938070292	0.245588801	normal	0.423044152	0.556687339	normal	0.360960965	0.296943568	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K00778|0|hsa:6480|ST6GAL1, SIAT1, ST6GalI, ST6N; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 (EC:2.4.99.1); K00778 beta-galactoside alpha-2,6-sialyltransferase (sialyltransferase 1) [EC:2.4.99.1] (A)"	N-Glycan biosynthesis (ko00510);; Other types of O-glycan biosynthesis (ko00514)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Beta-galactoside alpha-2,6-sialyltransferase 1 GN=ST6GAL1 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-galactoside alpha-2,6-sialyltransferase 1 isoform X1 [Ailuropoda melanoleuca] "
ENSG00000073861(TBX21)	--	0.0214306	1	0.0209399	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10166|0|ptr:749275|TBX21; T-box 21; K10166 T-box protein 21 (A)	Inflammatory bowel disease (IBD) (ko05321)	[K]	Transcription	T-box	T-box transcription factor TBX21 GN=TBX21 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: T-box transcription factor TBX21 [Tupaia chinensis]
ENSG00000073910(FRY)	--	0.032720041	8	0.110695981	14	0.124843432	27	0.01554324	4	0.04566067	9	0.136127759	7	--	--	--	--	--	--	0.306717461	-1.751300076	normal	--	--	--	--	--	--	--	--	[R]	General function prediction only	Cell morphogenesis N-terminal;; Cell morphogenesis C-terminal;; Cell morphogenesis central region	Protein furry homolog GN=FRY OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein furry homolog [Tupaia chinensis]
ENSG00000073921(PICALM)	--	44.51676957	2400	41.17932941	2311	43.91711082	2344	53.49145263	2891	50.06971609	2721	47.44574365	2471	0.967050092	0.237563218	normal	0.972356731	0.214063928	normal	0.987405126	0.067788398	normal	0.356515721	0.174590397	normal	--	--	Molecular Function: phospholipid binding (GO:0005543);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	ANTH domain;; ENTH domain	Phosphatidylinositol-binding clathrin assembly protein GN=PICALM OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: phosphatidylinositol-binding clathrin assembly protein isoform 2 [Ceratotherium simum simum]
ENSG00000073969(NSF)	--	19.71388883	1418	20.00839717	1440	18.8858713	1372	19.2416318	1426	19.25395678	1400	18.73652717	1378	0.983321922	-0.022691297	normal	0.981837338	-0.0620025	normal	0.983162594	-0.001993843	normal	0.914498188	-0.030260557	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K06027|0|hsa:4905|NSF, SKD2; N-ethylmaleimide-sensitive factor (EC:3.6.4.6); K06027 vesicle-fusing ATPase [EC:3.6.4.6] (A)"	Synaptic vesicle cycle (ko04721);; GABAergic synapse (ko04727);; Vasopressin-regulated water reabsorption (ko04962)	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATPase family associated with various cellular activities (AAA);; Cell division protein 48 (CDC48), domain 2;; Cell division protein 48 (CDC48), N-terminal domain;; AAA domain;; AAA domain;; AAA domain;; RNA helicase;; AAA domain (Cdc48 subfamily);; Holliday junction DNA helicase ruvB N-terminus;; AAA domain;; AAA domain (dynein-related subfamily);; AAA ATPase domain;; Part of AAA domain;; AAA domain;; TIP49 C-terminus;; Magnesium chelatase, subunit ChlI;; NACHT domain;; Zeta toxin;; Archaeal ATPase"	Vesicle-fusing ATPase GN=NSF OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: vesicle-fusing ATPase isoform X2 [Oryctolagus cuniculus]
ENSG00000074047(GLI2)	--	18.60608981	1524	36.98485276	1583	16.84588999	1811	17.08715726	1333	11.3999885	1324	16.48371991	1086	0.957975731	-0.223776926	normal	0.932296261	-0.278892913	normal	0.001568929	-0.745241291	normal	0.006560172	-0.415347014	normal	[R]	General function prediction only	--	"K16798|0|hsa:2736|GLI2, CJS, HPE9, PHS2, THP1, THP2; GLI family zinc finger 2; K16798 zinc finger protein GLI2 (A)"	Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein GLI2 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: zinc finger protein GLI2 [Condylura cristata]
ENSG00000074054(CLASP1)	--	11.22482877	1670	11.51028676	1692	11.31947746	1646	7.888056072	1164	7.876420286	1168	8.2345826	1213	0.152010559	-0.550978453	normal	0.159213696	-0.555514572	normal	0.561026071	-0.448194613	normal	0.000386676	-0.519555727	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K16578|0|ptr:459583|CLASP1; cytoplasmic linker associated protein 1; K16578 CLIP-associating protein 1/2 (A)	--	[R]	General function prediction only	CLASP N terminal;; HEAT repeat;; HEAT repeats;; HEAT-like repeat;; Guanine nucleotide exchange factor in Golgi transport N-terminal;; Vacuolar 14 Fab1-binding region;; non-SMC mitotic condensation complex subunit 1;; Rix1 complex component involved in 60S ribosome maturation	CLIP-associating protein 1 GN=CLASP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CLIP-associating protein 1 isoform X2 [Canis lupus familiaris]
ENSG00000074071(MRPS34)	--	97.7659	1770	86.42101	1597	93.71172	1752	95.77959	1761	100.47725	1825	85.40761	1561	0.985285312	-0.038153511	normal	0.974149531	0.170954072	normal	0.973267624	-0.174663859	normal	0.968742065	-0.013530316	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: mitochondrion (GO:0005739);; 	"K17412|3.92831e-133|hsa:65993|MRPS34, MRP-S12, MRP-S34, MRPS12; mitochondrial ribosomal protein S34; K17412 small subunit ribosomal protein S34 (A)"	--	--	--	--	"28S ribosomal protein S34, mitochondrial GN=MRPS34 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S34, mitochondrial [Galeopterus variegatus]"
ENSG00000074181(NOTCH3)	--	11.135376	1750	5.227381176	831	7.618235981	1162	4.954109246	754	7.848304579	1219	3.081428739	472	2.95E-11	-1.243835107	down	0.24120536	0.530549524	normal	1.31E-11	-1.305285489	down	0.411806356	-0.636262216	normal	[R]	General function prediction only	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: cell differentiation (GO:0030154);; 	"K02599|0|hsa:4854|NOTCH3, CADASIL, CASIL, IMF2; notch 3; K02599 Notch (A)"	Dorso-ventral axis formation (ko04320);; Notch signaling pathway (ko04330);; Thyroid hormone signaling pathway (ko04919);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	EGF-like domain;; Calcium-binding EGF domain;; Ankyrin repeats (3 copies);; Human growth factor-like EGF;; Ankyrin repeat;; LNR domain;; Ankyrin repeats (many copies);; NOTCH protein;; Ankyrin repeats (many copies);; NOTCH protein;; Ankyrin repeat;; EGF-like domain;; Domain of unknown function (DUF3454)	Notch 3 intracellular domain (Precursor) GN=NOTCH3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neurogenic locus notch homolog protein 3 [Odobenus rosmarus divergens]
ENSG00000074201(CLNS1A)	--	48.9183793	1263	48.85908014	1309	52.83586106	1286	68.59735032	1679	68.21639099	1544	56.71642074	1346	0.791900293	0.379513764	normal	0.960396183	0.216550531	normal	0.981588621	0.057430308	normal	0.215265481	0.222175284	normal	--	--	--	"K05019|5.70079e-136|cjc:100389699|CLNS1A; chloride channel, nucleotide-sensitive, 1A; K05019 chloride channel, nucleotide-sensitive, 1A (A)"	RNA transport (ko03013)	[P]	Inorganic ion transport and metabolism	Regulator of volume decrease after cellular swelling	Methylosome subunit pICln GN=CLNS1A OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: methylosome subunit pICln [Galeopterus variegatus]
ENSG00000074211(PPP2R2C)	--	19.85936329	1623	17.36577162	1539	20.84858812	1709	15.82293119	1335	13.96677948	1188	11.90028625	956	0.902962847	-0.312328887	normal	0.759765193	-0.394442435	normal	8.71E-05	-0.84534679	normal	0.000583134	-0.507558619	normal	[T]	Signal transduction mechanisms	--	"K04354|0|nle:100583131|PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma; K04354 serine/threonine-protein phosphatase 2A regulatory subunit B (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Dopaminergic synapse (ko04728);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	"WD domain, G-beta repeat"	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform GN=PPP2R2C OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform [Equus caballus]
ENSG00000074219(TEAD2)	--	16.598033	732	17.85919816	718	16.635359	721	12.4656503	551	15.291627	675	10.5147028	475	0.594063581	-0.439556104	normal	0.969243926	-0.110283279	normal	0.076112283	-0.608778313	normal	0.043621311	-0.373434369	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09448|0|pps:100969496|TEAD2; TEA domain family member 2; K09448 transcriptional enhancer factor (A)	Hippo signaling pathway (ko04390)	[K]	Transcription	TEA/ATTS domain family	Transcriptional enhancer factor TEF-4 GN=TEAD2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcriptional enhancer factor TEF-4 isoform X1 [Galeopterus variegatus]
ENSG00000074266(EED)	--	11.5491305	439	12.71570473	494	13.31993834	478	12.591622	479	11.80094732	441	9.88033695	359	0.966676311	0.094655259	normal	0.951100391	-0.184560566	normal	0.694791544	-0.419780328	normal	0.544984325	-0.163701676	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11462|0|mcf:102123827|EED; embryonic ectoderm development; K11462 polycomb protein EED (A)	--	[K]	Transcription	"WD domain, G-beta repeat"	Polycomb protein EED GN=EED OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: polycomb protein EED isoform 1 [Odobenus rosmarus divergens] 
ENSG00000074276(CDHR2)	--	0.040263902	4	0.0299095	3	0.00974588	0	0.0504635	5	0.0293515	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16502|0|hsa:54825|CDHR2, PCDH24, PCLKC; cadherin-related family member 2; K16502 cadherin-related family member 2 (A)"	--	[S]	Function unknown	Cadherin domain	Cadherin-related family member 2 (Precursor) GN=CDHR2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cadherin-related family member 2 [Eptesicus fuscus]
ENSG00000074317(SNCB)	--	0.703397601	15	0.745133512	19	0.687203236	14	0.327090005	8	0.222513037	4	0.045724742	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Synuclein	Beta-synuclein GN=SNCB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: beta-synuclein [Oryctolagus cuniculus]
ENSG00000074319(TSG101)	--	33.6624588	1093	31.771315	1033	33.019339	1067	27.571086	901	30.058232	974	33.069084	1077	0.892469105	-0.309047268	normal	0.974596836	-0.10611312	normal	0.980403102	0.005159353	normal	0.54017547	-0.133847013	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; Biological Process: protein transport (GO:0015031);; 	K12183|0|ptr:451065|TSG101; tumor susceptibility 101; K12183 ESCRT-I complex subunit TSG101 (A)	Endocytosis (ko04144)	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	UEV domain;; Vps23 core domain	Tumor susceptibility gene 101 protein GN=TSG101 OS=Homo sapiens (Human) PE=1 SV=2	OU	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: tumor susceptibility gene 101 protein isoform X1 [Galeopterus variegatus]
ENSG00000074356(NCBP3)	--	6.5033938	1479	8.383241	1382	6.17838616	1405	7.261776347	1475	7.08767381	1614	9.942157899	1367	0.983512253	-0.034703262	normal	0.965382716	0.202251447	normal	0.982512531	-0.047796171	normal	0.880323281	0.041505414	normal	--	--	Molecular Function: RNA 7-methylguanosine cap binding (GO:0000340);; Molecular Function: mRNA binding (GO:0003729);; 	--	--	--	--	Protein of unknown function (DUF2414)	Uncharacterized protein C17orf85 GN=C17orf85 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C17orf85 homolog isoform X3 [Galeopterus variegatus]
ENSG00000074370(ATP2A3)	--	8.975142692	864	5.818469593	561	5.732050811	554	4.484990576	438	7.36058788	704	4.87420466	461	1.95E-06	-1.008362729	down	0.888781773	0.305411805	normal	0.913666248	-0.272593729	normal	0.557787019	-0.325146779	normal	[P]	Inorganic ion transport and metabolism	--	"K05853|0|pon:100446409|ATP2A3; ATPase, Ca++ transporting, ubiquitous; K05853 Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 GN=ATP2A3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform 1 [Ceratotherium simum simum]
ENSG00000074410(CA12)	--	181.5540255	16523	179.1595692	15719	168.8953303	14956	160.9583501	14354	133.6305458	11907	199.5117255	18055	0.991712517	-0.233831738	normal	0.894141368	-0.422079208	normal	0.989173465	0.263358332	normal	0.739402947	-0.111583805	normal	[P]	Inorganic ion transport and metabolism	--	K01672|0|pps:100970519|CA12; carbonic anhydrase XII; K01672 carbonic anhydrase [EC:4.2.1.1] (A)	Nitrogen metabolism (ko00910)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase 12 (Precursor) GN=CA12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carbonic anhydrase 12 isoform X1 [Orycteropus afer afer]
ENSG00000074416(MGLL)	--	9.581741063	830	9.976215692	805	9.922805557	854	32.93276742	2837	32.85793242	2618	36.45678114	3127	0	1.740500386	up	0	1.678129523	up	0	1.862334178	up	9.73E-41	1.764894564	up	[I]	Lipid transport and metabolism	Biological Process: lipid metabolic process (GO:0006629);; 	K01054|0|pps:100968239|MGLL; monoglyceride lipase; K01054 acylglycerol lipase [EC:3.1.1.23] (A)	Glycerolipid metabolism (ko00561);; Retrograde endocannabinoid signaling (ko04723)	[I]	Lipid transport and metabolism	Alpha/beta hydrolase family;; Putative lysophospholipase;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Lipase (class 3);; Putative esterase;; alpha/beta hydrolase fold;; Dienelactone hydrolase family	Monoglyceride lipase GN=MGLL OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: monoglyceride lipase isoform X1 [Galeopterus variegatus]
ENSG00000074527(NTN4)	--	56.42293844	3844	86.39698077	5814	60.852495	4089	37.5820518	2522	32.79994169	2189	46.0556753	3116	0.025636334	-0.638554655	normal	8.88E-16	-1.430054351	down	0.812359397	-0.400174187	normal	0.016611382	-0.833573853	normal	--	--	--	"K06845|0|hsa:59277|NTN4, PRO3091; netrin 4; K06845 netrin 4 (A)"	Axon guidance (ko04360)	[W]	Extracellular structures	Laminin N-terminal (Domain VI);; Laminin EGF-like (Domains III and V);; UNC-6/NTR/C345C module	Netrin-4 (Precursor) GN=NTN4 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: netrin-4 isoform X1 [Vicugna pacos]
ENSG00000074582(BCS1L)	--	17.131381	445	18.617936	454	19.575868	504	11.813689	289	12.28637925	297	13.111975	294	0.066027534	-0.650756419	normal	0.097692216	-0.631036367	normal	0.004044021	-0.782785863	normal	0.000404731	-0.693858206	normal	--	--	Molecular Function: ATP binding (GO:0005524);; Biological Process: mitochondrial respiratory chain complex III assembly (GO:0034551);; 	K08900|0|pps:100988698|BCS1L; mitochondrial chaperone BCS1; K08900 mitochondrial chaperone BCS1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	BCS1 N terminal;; ATPase family associated with various cellular activities (AAA)	Mitochondrial chaperone BCS1 GN=BCS1L OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial chaperone BCS1 [Galeopterus variegatus] 
ENSG00000074590(NUAK1)	--	4.562801534	495	4.73872	561	5.12195	584	13.092305	1309	14.86274351	1585	12.019318	1185	5.55E-13	1.369419405	up	4.66E-15	1.474514631	up	7.94E-07	1.010680237	up	1.51E-10	1.293338173	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08800|0|hsa:9891|NUAK1, ARK5; NUAK family, SNF1-like kinase, 1 (EC:2.7.11.1); K08800 NUAK family, SNF1-like kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; RIO1 family;; Lipopolysaccharide kinase (Kdo/WaaP) family	NUAK family SNF1-like kinase 1 GN=NUAK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: NUAK family SNF1-like kinase 1, partial [Tupaia chinensis]"
ENSG00000074603(DPP8)	--	13.0704534	1295	13.97108505	1381	13.02378184	1291	15.14162473	1525	16.31845088	1703	13.74684512	1349	0.963543831	0.204800788	normal	0.932990279	0.280661362	normal	0.981715135	0.055046821	normal	0.33111559	0.184826334	normal	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Molecular Function: hydrolase activity (GO:0016787);; 	K08655|0|aml:100475695|DPP8; dipeptidyl-peptidase 8; K08655 dipeptidyl-peptidase 8 [EC:3.4.14.5] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Dipeptidyl peptidase IV (DPP IV) N-terminal region;; Prolyl oligopeptidase family;; X-Pro dipeptidyl-peptidase (S15 family);; Alpha/beta hydrolase family	Dipeptidyl peptidase 8 GN=DPP8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dipeptidyl peptidase 8 isoform X1 [Ailuropoda melanoleuca]
ENSG00000074621(SLC24A1)	--	3.006073644	297	3.507373003	276	1.9528078	247	2.661761039	248	2.578891921	276	3.816703195	332	0.908530344	-0.289314501	normal	0.966265387	-0.021309797	normal	0.749178772	0.416175312	normal	0.926977546	0.041434682	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13749|0|ptr:453521|SLC24A1; solute carrier family 24 (sodium/potassium/calcium exchanger), member 1; K13749 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 (A)"	Phototransduction (ko04744)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Sodium/calcium exchanger protein	Sodium/potassium/calcium exchanger 1 GN=SLC24A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium/calcium exchanger 1 isoform X1 [Camelus bactrianus]
ENSG00000074657(ZNF532)	--	15.06878723	1259	22.77435034	1481	12.58832764	1112	15.66631718	1185	17.37538215	1428	17.95497889	1465	0.976490676	-0.118074925	normal	0.981570269	-0.073925337	normal	0.76134791	0.388990144	normal	0.855593371	0.061340619	normal	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 532 GN=ZNF532 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 532 [Camelus ferus] 
ENSG00000074660(SCARF1)	--	0.094035669	5	0.292608841	19	0.070730124	3	0.06758554	4	0.303886384	18	0.234598795	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin EGF-like (Domains III and V);; Human growth factor-like EGF;; Coiled-coil domain-containing glutamate-rich protein family 1	Scavenger receptor class F member 1 (Precursor) GN=SCARF1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: scavenger receptor class F member 1 isoform 1 [Ceratotherium simum simum]
ENSG00000074695(LMAN1)	--	51.6146	3910	48.1891	3648	46.8202	3541	42.3199	3264	39.0755	3015	40.1781	3047	0.952979812	-0.29123435	normal	0.948971577	-0.296238967	normal	0.974694225	-0.224955112	normal	0.10726214	-0.272619995	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K10080|0|hsa:3998|LMAN1, ERGIC-53, ERGIC53, F5F8D, FMFD1, MCFD1, MR60, gp58; lectin, mannose-binding, 1; K10080 lectin, mannose-binding 1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Legume-like lectin family	Protein ERGIC-53 (Precursor) GN=LMAN1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein ERGIC-53 [Ceratotherium simum simum]
ENSG00000074696(HACD3)	--	120.4106494	6756	119.7972201	6719	123.8332734	6890	141.9299801	8045	133.4774553	7488	121.6440342	6873	0.986677264	0.221044719	normal	0.992553064	0.13487858	normal	0.994883169	-0.011852861	normal	0.612625624	0.116172455	normal	--	--	--	--	--	--	--	--	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 GN=PTPLAD1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 3 [Oryctolagus cuniculus]
ENSG00000074706(IPCEF1)	--	0.032619451	1	0.008435237	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	PH domain	Interactor protein for cytohesin exchange factors 1 GN=IPCEF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interactor protein for cytohesin exchange factors 1 isoform X1 [Mustela putorius furo] 
ENSG00000074755(ZZEF1)	--	9.159343	2171	9.434074	2241	8.9992522	2220	10.01252	2462	10.75726	2617	11.679878	2788	0.981470752	0.150538686	normal	0.974244746	0.202218338	normal	0.918042626	0.320184413	normal	0.200425306	0.225567981	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	"Zinc finger, ZZ type;; Anaphase-promoting complex, subunit 10 (APC10)"	Zinc finger ZZ-type and EF-hand domain-containing protein 1 GN=ZZEF1 OS=Homo sapiens (Human) PE=1 SV=6	R	General function prediction only	PREDICTED: zinc finger ZZ-type and EF-hand domain-containing protein 1 [Galeopterus variegatus]
ENSG00000074800(ENO1)	--	1407.407969	48062	1376.609838	47603	1367.279898	46907	1434.542091	49069	1184.526241	40136	1293.75169	44115	0.999028916	-0.000917049	normal	0.994978025	-0.267572941	normal	0.998718686	-0.096822172	normal	0.688053297	-0.118427827	normal	[G]	Carbohydrate transport and metabolism	--	"K01689|0|ptr:457913|ENO1; enolase 1, (alpha) (EC:4.2.1.11); K01689 enolase [EC:4.2.1.11] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; RNA degradation (ko03018);; HIF-1 signaling pathway (ko04066)	[G]	Carbohydrate transport and metabolism	"Enolase, C-terminal TIM barrel domain;; Enolase, N-terminal domain;; Enolase C-terminal domain-like"	Alpha-enolase GN=ENO1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: alpha-enolase-like [Tupaia chinensis] 
ENSG00000074842(MYDGF)	--	70.6094	1118	69.6399	1150	65.591589	1062	82.255751	1347	77.2565	1216	93.5331	1490	0.949145017	0.237699467	normal	0.979814733	0.059007345	normal	0.420005081	0.479657817	normal	0.133670677	0.2624101	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0556	UPF0556 protein C19orf10 (Precursor) GN=C19orf10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0556 protein C19orf10 homolog [Leptonychotes weddellii]
ENSG00000074855(ANO8)	--	3.735535	344	3.623789	339	3.188123	291	2.900737	267	2.62385182	250	3.300364	298	0.783636664	-0.394395458	normal	0.648166102	-0.458392535	normal	0.967509229	0.025868885	normal	0.306043216	-0.278292289	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Calcium-activated chloride channel	Anoctamin-8 GN=ANO8 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anoctamin-8 isoform X3 [Mustela putorius furo]
ENSG00000074935(TUBE1)	--	4.85240131	142	4.6855016	146	6.71718522	190	2.963354035	80	2.54432944	86	4.81943409	144	0.088033575	-0.846276643	normal	0.176597182	-0.774409216	normal	0.843207336	-0.404511592	normal	0.091392909	-0.643649338	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K10391|0|hsa:51175|TUBE1, TUBE, dJ142L7.2; tubulin, epsilon 1; K10391 tubulin epsilon (A)"	--	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin epsilon chain GN=TUBE1 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: tubulin epsilon chain isoform X1 [Ailuropoda melanoleuca] 
ENSG00000074964(ARHGEF10L)	--	4.48994526	409	4.125386094	398	4.449841778	433	5.609973764	516	5.398639979	497	6.79259977	627	0.888496912	0.303421332	normal	0.894210215	0.298035682	normal	0.300061455	0.524276935	normal	0.06127613	0.382856932	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K16727|0|pps:100986864|ARHGEF10L; Rho guanine nucleotide exchange factor (GEF) 10-like; K16727 Rho guanine nucleotide exchange factor 10 (A)	--	[T]	Signal transduction mechanisms	RhoGEF domain	Rho guanine nucleotide exchange factor 10-like protein GN=ARHGEF10L OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 10-like protein isoform X3 [Tupaia chinensis] 
ENSG00000074966(TXK)	--	1.367078724	116	2.539995958	148	1.687273008	139	1.3941311	103	1.282741502	88	1.300324754	134	0.958969818	-0.199506284	normal	0.193142551	-0.761243605	normal	0.967286737	-0.060473181	normal	0.424413392	-0.330747389	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08016|0|hsa:7294|TXK, BTKL, PSCTK5, PTK4, RLK, TKL; TXK tyrosine kinase (EC:2.7.10.2); K08016 tyrosine-protein kinase TXK [EC:2.7.10.2] (A)"	Leukocyte transendothelial migration (ko04670)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain	Tyrosine-protein kinase TXK GN=TXK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase TXK isoform X2 [Camelus dromedarius]
ENSG00000075043(KCNQ2)	--	0.17360213	3	0.0474645	1	0	0	0.097092107	4	0.142878619	3	0.242602063	5	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: potassium channel activity (GO:0005267);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04927|0|pps:100971963|KCNQ2; potassium voltage-gated channel, KQT-like subfamily, member 2; K04927 potassium voltage-gated channel KQT-like subfamily member 2 (A)"	Cholinergic synapse (ko04725)	[P]	Inorganic ion transport and metabolism	KCNQ voltage-gated potassium channel;; Ankyrin-G binding motif of KCNQ2-3;; Ion transport protein;; Ion channel	Potassium voltage-gated channel subfamily KQT member 2 GN=KCNQ2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily KQT member 2 isoform 2 [Ceratotherium simum simum]
ENSG00000075073(TACR2)	--	0.247264545	7	0.039349473	1	0.077305801	1	0.118067931	4	0.103136494	2	0.2461162	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04223|0|hsa:6865|TACR2, NK2R, NKNAR, SKR, TAC2R; tachykinin receptor 2; K04223 tachykinin receptor 2 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Substance-K receptor GN=TACR2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: substance-K receptor [Galeopterus variegatus]
ENSG00000075089(ACTR6)	--	14.24225	400	15.621881	419	16.72241	437	16.59317	463	15.104159	417	14.103273	401	0.952300194	0.179538544	normal	0.968943891	-0.028227295	normal	0.961533427	-0.131846012	normal	0.989291545	0.006896255	normal	[Z]	Cytoskeleton	--	K11662|0|ptr:452159|ACTR6; ARP6 actin-related protein 6 homolog (yeast); K11662 actin-related protein 6 (A)	--	[Z]	Cytoskeleton	Actin	Actin-related protein 6 GN=ACTR6 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: actin-related protein 6 isoform X1 [Canis lupus familiaris]
ENSG00000075131(TIPIN)	--	15.683136	567	15.18764	556	14.32412	534	12.46097575	487	13.6380834	460	9.612089	371	0.927641651	-0.249528747	normal	0.89752049	-0.293996935	normal	0.300349963	-0.531894567	normal	0.088027309	-0.35226458	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: cellular response to DNA damage stimulus (GO:0006974);; Biological Process: cell cycle (GO:0007049);; Biological Process: replication fork protection (GO:0048478);; 	K10904|0|pps:100990227|TIPIN; TIMELESS interacting protein; K10904 TIMELESS-interacting protein (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Replication Fork Protection Component Swi3	TIMELESS-interacting protein GN=TIPIN OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: TIMELESS-interacting protein [Physeter catodon]
ENSG00000075142(SRI)	--	71.23513819	1225	65.16125956	1136	57.64247272	1049	54.11915774	901	46.52654793	829	43.424652	796	0.442790714	-0.473319702	normal	0.458416927	-0.475201518	normal	0.701253595	-0.405791997	normal	0.004018714	-0.454684874	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand	Sorcin GN=SRI OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	sorcin isoform 2 [Sus scrofa]
ENSG00000075151(EIF4G3)	--	19.71183818	2424	22.82757814	2813	21.0358639	2346	16.08668882	2006	18.27699072	2176	19.27929898	2293	0.927418067	-0.303688374	normal	0.810829768	-0.391617448	normal	0.98779034	-0.041231216	normal	0.145685588	-0.24888596	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	"K03260|0|aml:100465360|EIF4G3; eukaryotic translation initiation factor 4 gamma, 3; K03260 translation initiation factor 4G (A)"	RNA transport (ko03013);; Viral myocarditis (ko05416)	[J]	"Translation, ribosomal structure and biogenesis"	MIF4G domain;; MA3 domain;; eIF4-gamma/eIF5/eIF2-epsilon	Eukaryotic translation initiation factor 4 gamma 3 GN=EIF4G3 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4 gamma 3 isoform X9 [Mustela putorius furo]
ENSG00000075188(NUP37)	--	46.41601144	743	46.45933691	738	45.159467	736	55.85069561	893	55.12366138	861	45.3591664	689	0.941867088	0.234023807	normal	0.953926975	0.200585024	normal	0.970910249	-0.10327386	normal	0.624077398	0.118128203	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14302|0|ptr:452180|NUP37; nucleoporin 37kDa; K14302 nuclear pore complex protein Nup37 (A)	RNA transport (ko03013)	[R]	General function prediction only	"WD domain, G-beta repeat"	Nucleoporin Nup37 GN=NUP37 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nucleoporin Nup37 [Camelus ferus] 
ENSG00000075213(SEMA3A)	--	43.80221917	2493	38.58752955	2886	54.33876164	2700	20.81735821	1233	23.54307496	1349	13.47968432	1145	4.90E-08	-1.045605882	down	4.53E-09	-1.117729269	down	1.04E-11	-1.244799079	down	1.07E-17	-1.137522478	down	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06840|0|ptr:745878|SEMA3A; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A; K06840 semaphorin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain	Semaphorin-3A (Precursor) GN=SEMA3A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-3A [Trichechus manatus latirostris]
ENSG00000075218(GTSE1)	--	14.98366422	1085	14.65067	1081	14.363135	1061	14.86279829	1091	14.60228936	1058	14.081657	1050	0.980334562	-0.022843946	normal	0.978877951	-0.052379382	normal	0.980040983	-0.023293396	normal	0.907236874	-0.033916298	normal	--	--	--	"K10129|0|hsa:51512|GTSE1, B99; G-2 and S-phase expressed 1; K10129 G-2 and S-phase expressed protein 1 (A)"	p53 signaling pathway (ko04115)	--	--	G-2 and S-phase expressed 1	G2 and S phase-expressed protein 1 GN=GTSE1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: G2 and S phase-expressed protein 1 [Ceratotherium simum simum]
ENSG00000075223(SEMA3C)	--	60.256381	4997	58.81671	4843	64.09722	5210	65.79620378	5485	62.608284	5143	55.17850316	4585	0.992094316	0.103566739	normal	0.992582632	0.065262816	normal	0.985583301	-0.192593445	normal	0.987123827	-0.006065268	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06840|0|hsa:10512|SEMA3C, SEMAE, SemE; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; K06840 semaphorin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Immunoglobulin I-set domain	Semaphorin-3C (Precursor) GN=SEMA3C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: semaphorin-3C [Galeopterus variegatus]
ENSG00000075234(TTC38)	--	5.182874318	255	4.944163388	243	4.528112238	224	5.821166742	286	7.352415	345	5.463513924	269	0.959115182	0.133923449	normal	0.582630309	0.481685998	normal	0.929036888	0.254247618	normal	0.288238598	0.296505004	normal	--	--	--	--	--	[S]	Function unknown	Tetratricopeptide repeat	Tetratricopeptide repeat protein 38 GN=TTC38 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 38 [Sus scrofa]
ENSG00000075239(ACAT1)	--	36.42346152	1136	40.27679178	1286	38.28862141	1202	40.19719437	1264	37.67774756	1163	42.2091107	1310	0.975692595	0.123043557	normal	0.96954092	-0.1662604	normal	0.977154061	0.115699	normal	0.94174249	0.023136934	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K00626|0|ptr:451528|ACAT1; acetyl-CoA acetyltransferase 1; K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] (A)	"Fatty acid degradation (ko00071);; Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Pyruvate metabolism (ko00620);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; Terpenoid backbone biosynthesis (ko00900);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	"Thiolase, N-terminal domain;; Thiolase, C-terminal domain;; Beta-ketoacyl synthase, N-terminal domain"	"Acetyl-CoA acetyltransferase, mitochondrial (Precursor) GN=ACAT1 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: acetyl-CoA acetyltransferase, mitochondrial [Tursiops truncatus]"
ENSG00000075240(GRAMD4)	--	6.610589274	532	6.203734211	434	5.109078493	411	5.774454112	437	7.946252258	470	5.114049863	426	0.877898682	-0.313623917	normal	0.965948234	0.093226947	normal	0.969343734	0.043267214	normal	0.83770879	-0.068304759	normal	--	--	--	--	--	--	--	GRAM domain	GRAM domain-containing protein 4 GN=GRAMD4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: GRAM domain-containing protein 4 isoform X1 [Felis catus] 
ENSG00000075275(CELSR1)	--	18.56474451	4037	17.6173837	3564	21.243177	4243	18.22285808	3874	19.20539964	4174	21.85762039	4722	0.990668596	-0.090256826	normal	0.980705756	0.206425701	normal	0.988850405	0.145972582	normal	0.710620391	0.088237399	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04600|0|hsa:9620|CELSR1, CDHF9, FMI2, HFMI2, ME2; cadherin, EGF LAG seven-pass G-type receptor 1; K04600 cadherin EGF LAG seven-pass G-type receptor 1 (A)"	--	[T]	Signal transduction mechanisms	Cadherin domain;; Domain of unknown function (DUF3497);; Laminin G domain;; 7 transmembrane receptor (Secretin family);; Laminin G domain;; Latrophilin/CL-1-like GPS domain;; EGF-like domain;; Hormone receptor domain;; Laminin EGF-like (Domains III and V);; Slime mold cyclic AMP receptor;; Cadherin prodomain like	Cadherin EGF LAG seven-pass G-type receptor 1 (Precursor) GN=CELSR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cadherin EGF LAG seven-pass G-type receptor 1 [Odobenus rosmarus divergens]
ENSG00000075290(WNT8B)	--	0.203204	7	0.0283704	1	0	0	0.0859255	3	0.0281927	0	0.028507	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00714|0|hsa:7479|WNT8B; wingless-type MMTV integration site family, member 8B; K00714 wingless-type MMTV integration site family, member 8 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-8b (Precursor) GN=WNT8B OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: protein Wnt-8b [Physeter catodon]
ENSG00000075292(ZNF638)	--	21.74512342	2349	29.49218981	2663	25.0868889	2659	22.90315405	2421	24.49853604	2259	22.50744065	2430	0.988390445	0.01271591	normal	0.958297146	-0.258635036	normal	0.983847283	-0.138136692	normal	0.528079683	-0.130691721	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 638 GN=ZNF638 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 638 isoform 1 [Ceratotherium simum simum] 
ENSG00000075303(SLC25A40)	--	8.395161218	422	8.938520066	447	10.17782445	504	8.176916	420	6.813905272	345	9.14395	461	0.969497017	-0.0375489	normal	0.765909766	-0.393584676	normal	0.962099723	-0.13651995	normal	0.485777474	-0.18410666	normal	--	--	--	"K15119|0|hsa:55972|SLC25A40, MCFP; solute carrier family 25, member 40; K15119 solute carrier family 25, member 39/40 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 40 GN=SLC25A40 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 40 [Odobenus rosmarus divergens]
ENSG00000075336(TIMM21)	--	8.500986282	395	8.773417848	428	10.3915033	478	9.2655348	416	7.923302986	365	7.8531042	363	0.968948261	0.043732851	normal	0.925819471	-0.250182471	normal	0.73444729	-0.403861504	normal	0.427630066	-0.206916726	normal	--	--	Cellular Component: mitochondrial inner membrane presequence translocase complex (GO:0005744);; Biological Process: protein import into mitochondrial matrix (GO:0030150);; 	"K17796|0|hsa:29090|TIMM21, C18orf55, TIM21; translocase of inner mitochondrial membrane 21 homolog (yeast); K17796 mitochondrial import inner membrane translocase subunit TIM21 (A)"	--	[S]	Function unknown	TIM21;; Cytochrome oxidase complex assembly protein 1	Mitochondrial import inner membrane translocase subunit Tim21 (Precursor) GN=TIMM21 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: mitochondrial import inner membrane translocase subunit Tim21 [Ceratotherium simum simum]
ENSG00000075340(ADD2)	--	21.90875025	2622	19.71076075	2499	26.7065592	2592	18.90173739	2238	16.28651284	1968	17.00644639	1933	0.957222658	-0.259125343	normal	0.855236892	-0.365797129	normal	0.666670578	-0.431223096	normal	0.025058264	-0.350925118	normal	[G]	Carbohydrate transport and metabolism	--	"K18622|0|hsa:119|ADD2, ADDB; adducin 2 (beta); K18622 adducin (A)"	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Class II Aldolase and Adducin N-terminal domain	Beta-adducin GN=ADD2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: beta-adducin-like isoform X1 [Panthera tigris altaica] 
ENSG00000075391(RASAL2)	--	4.85733361	884	5.654782001	987	5.285023854	868	7.80401314	1452	5.622599	1085	6.60262591	1217	0.008903198	0.684154413	normal	0.974143007	0.114978429	normal	0.423355452	0.478563392	normal	0.019500364	0.432765617	normal	--	--	Biological Process: regulation of GTPase activity (GO:0043087);; 	K17633|0|pps:100973926|RASAL2; RAS protein activator like 2; K17633 RAS protein activator-like 2 (A)	Ras signaling pathway (ko04014)	[R]	General function prediction only	Domain of unknown function (DUF3498);; GTPase-activator protein for Ras-like GTPase;; PH domain;; C2 domain	Ras GTPase-activating protein nGAP GN=RASAL2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating protein nGAP isoform X4 [Equus caballus]
ENSG00000075399(VPS9D1)	--	4.202115169	210	3.113346	161	2.756277	157	5.719205	242	4.4817908	238	7.41449529	310	0.953323485	0.172608377	normal	0.53046733	0.538291639	normal	0.000471842	0.966462624	normal	0.032489162	0.560615837	normal	--	--	--	--	--	--	--	Vacuolar sorting protein 9 (VPS9) domain	VPS9 domain-containing protein 1 GN=VPS9D1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: VPS9 domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000075407(ZNF37A)	--	4.760351835	780	4.664621394	771	5.008709576	814	4.56690512	761	4.476620187	726	4.66475892	786	0.974670857	-0.066277753	normal	0.970444953	-0.107969581	normal	0.975624027	-0.058679974	normal	0.771144784	-0.078267653	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7587|ZNF37A, KOX21, ZNF37; zinc finger protein 37A; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; TFIIH C1-like domain"	Zinc finger protein 37A GN=ZNF37A OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 37A-like [Odobenus rosmarus divergens]
ENSG00000075413(MARK3)	--	22.13415272	1317	22.80804003	1339	20.571259	1221	24.96863143	1488	27.512639	1614	25.8964981	1599	0.975213035	0.145127571	normal	0.949604706	0.247802836	normal	0.788038733	0.38040239	normal	0.137351462	0.256929452	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08798|0|hsa:4140|MARK3, CTAK1, KP78, PAR1A, Par-1a; MAP/microtubule affinity-regulating kinase 3 (EC:2.7.11.1); K08798 MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase associated domain 1;; Kinase-like	MAP/microtubule affinity-regulating kinase 3 GN=MARK3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: MAP/microtubule affinity-regulating kinase 3 isoform X24 [Canis lupus familiaris]
ENSG00000075415(SLC25A3)	--	457.1064315	8878	427.053056	8489	439.0123777	8644	491.8357407	9960	466.8474707	9213	522.6101029	10127	0.994235806	0.135056696	normal	0.994789159	0.096633313	normal	0.989000339	0.220108825	normal	0.497437647	0.150605419	normal	--	--	--	"K15102|0|pps:100967899|SLC25A3; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3; K15102 solute carrier family 25 (mitochondrial phosphate transporter), member 3 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	"Phosphate carrier protein, mitochondrial (Precursor) GN=SLC25A3 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: phosphate carrier protein, mitochondrial isoform X1 [Chrysochloris asiatica]"
ENSG00000075420(FNDC3B)	--	36.95459624	3908	43.16464289	4357	33.97130593	3791	36.62046885	4202	36.17776254	3777	46.3291466	5124	0.991333386	0.073785453	normal	0.977760092	-0.227436015	normal	0.760720457	0.426253786	normal	0.732172607	0.099329702	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Fibronectin type III domain;; Interferon-alpha/beta receptor, fibronectin type III;; SusE outer membrane protein"	Fibronectin type III domain-containing protein 3B GN=UNQ2421/PRO4979/PRO34274 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: fibronectin type III domain-containing protein 3B [Ceratotherium simum simum]
ENSG00000075426(FOSL2)	--	35.80658814	4300	38.409186	4656	42.63529609	5121	61.86381555	7391	65.89389748	7826	80.49069079	9615	0.001441187	0.750393832	normal	0.004032531	0.727573283	normal	9.98E-06	0.900372647	normal	2.74E-05	0.798685372	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09030|2.38223e-170|mcf:102134363|FOSL2; FOS-like antigen 2; K09030 fos-like antigen 2 (A)	Osteoclast differentiation (ko04380)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Fos-related antigen 2 GN=FOSL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: fos-related antigen 2 [Galeopterus variegatus]
ENSG00000075461(CACNG4)	--	5.253764	317	6.828655	316	5.792344	286	5.827476	281	7.142200009	326	4.092125386	187	0.944789558	-0.203695524	normal	0.967015741	0.023410545	normal	0.221341802	-0.617201426	normal	0.512876976	-0.233200406	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K04869|0|hsa:27092|CACNG4; calcium channel, voltage-dependent, gamma subunit 4; K04869 voltage-dependent calcium channel gamma-4 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Voltage-dependent calcium channel gamma-4 subunit GN=CACNG4 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent calcium channel gamma-4 subunit [Trichechus manatus latirostris]
ENSG00000075539(FRYL)	--	4.786030082	1003	5.437425644	1067	5.714324348	1065	6.15746222	1227	4.952306752	968	4.468803725	958	0.935610015	0.259621336	normal	0.967343057	-0.161667095	normal	0.967818199	-0.16080643	normal	0.971851655	-0.013727573	normal	--	--	--	--	--	[R]	General function prediction only	Cell morphogenesis N-terminal;; Cell morphogenesis C-terminal;; Cell morphogenesis central region	Protein furry homolog-like GN=FRYL OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein furry homolog-like [Trichechus manatus latirostris]
ENSG00000075568(TMEM131)	--	16.56799227	2206	15.656537	2046	16.8590443	2200	11.73660375	1554	10.62337698	1422	10.95588149	1469	0.202250951	-0.535831357	normal	0.190469158	-0.545824427	normal	0.071631563	-0.590460388	normal	9.23E-05	-0.558875762	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF3651)	Transmembrane protein 131 GN=TMEM131 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transmembrane protein 131 [Canis lupus familiaris]
ENSG00000075618(FSCN1)	--	176.013269	7992	165.9825727	7621	177.9907917	8356	185.56115	8469	194.0245252	8861	136.716984	6276	0.995355607	0.052792923	normal	0.990015319	0.196026547	normal	0.830093086	-0.421170317	normal	0.895327936	-0.043825481	normal	--	--	"Molecular Function: protein binding, bridging (GO:0030674);; Molecular Function: actin filament binding (GO:0051015);; "	K17455|0|ptr:463247|FSCN1; fascin actin-bundling protein 1; K17455 fascin 1/2 (A)	--	--	--	Fascin domain;; FRG1-like family;; Protein of unknown function (DUF569)	Fascin GN=FSCN1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: fascin isoform 1 [Canis lupus familiaris]
ENSG00000075624(ACTB)	--	2171.024536	71315	2393.190037	78710	2318.340037	77113	3283.783299	109467	3029.91946	99655	2505.331526	82920	0.516064096	0.587376009	normal	0.994823499	0.318963236	normal	0.999210083	0.096452754	normal	0.148960058	0.34063557	normal	[Z]	Cytoskeleton	--	"K05692|0|bacu:103015338|ACTB; actin, beta; K05692 actin beta/gamma 1 (A)"	Rap1 signaling pathway (ko04015);; Phagosome (ko04145);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132);; Influenza A (ko05164);; Proteoglycans in cancer (ko05205);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	[Z]	Cytoskeleton	Actin	"Actin, cytoplasmic 1, N-terminally processed GN=ACTB OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: actin, cytoplasmic 1 [Camelus dromedarius]"
ENSG00000075643(MOCOS)	--	3.0771435	336	2.855980131	311	3.149892556	340	4.687041961	510	4.480563812	487	5.34017253	584	0.199294743	0.569077909	normal	0.103489705	0.62314038	normal	0.003901399	0.769499582	normal	0.000508755	0.659008851	normal	[E]	Amino acid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: molybdenum ion binding (GO:0030151);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K15631|0|hsa:55034|MOCOS, HMCS, MCS, MOS; molybdenum cofactor sulfurase (EC:2.8.1.9); K15631 molybdenum cofactor sulfurtransferase [EC:2.8.1.9] (A)"	--	[H]	Coenzyme transport and metabolism	MOSC N-terminal beta barrel domain;; MOSC domain;; Aminotransferase class-V	Molybdenum cofactor sulfurase {ECO:0000255|HAMAP-Rule:MF_03050} OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: molybdenum cofactor sulfurase [Ceratotherium simum simum]
ENSG00000075651(PLD1)-2	--	8.369889661	799	8.122586817	803	7.612055186	722	7.011615977	714	6.479772517	625	12.17204808	1284	0.955545548	-0.1927114	normal	0.770532416	-0.38215221	normal	0.000255179	0.820976076	normal	0.843124521	0.155017581	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000075651(PLD1)-3	--	0.451195	21	0.611157	29	0.825232	38	0.614799	29	0.502307	23	0.809898	38	0.979520956	0.40926613	normal	0.979981864	-0.336119878	normal	0.982119819	-0.007974097	normal	1	0.01271525	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000075673(ATP12A)	--	0	0	0	0	0.025479758	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K01544|0|hsa:479|ATP12A, ATP1AL1; ATPase, H+/K+ transporting, nongastric, alpha polypeptide (EC:3.6.3.10); K01544 non-gastric H+/K+-exchanging ATPase [EC:3.6.3.10] (A)"	Oxidative phosphorylation (ko00190)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase"	Potassium-transporting ATPase alpha chain 2 GN=ATP12A OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: potassium-transporting ATPase alpha chain 2 [Equus przewalskii]
ENSG00000075702(WDR62)	--	14.11952008	1473	15.73858683	1653	15.91556635	1681	10.111127	1047	9.83161687	1018	11.35556265	1185	0.24152329	-0.522678071	normal	0.004155891	-0.719927716	normal	0.28426833	-0.512172431	normal	5.08E-05	-0.585429273	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 62 GN=WDR62 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: WD repeat-containing protein 62 isoform X1 [Galeopterus variegatus]
ENSG00000075711(DLG1)	--	16.90439647	856	13.6597017	892	14.68897733	872	18.58830561	1164	21.36959087	1124	26.64491176	1180	0.682727001	0.411939888	normal	0.892606421	0.311628301	normal	0.63073457	0.427455772	normal	0.019008077	0.383361393	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12076|0|ggo:101132886|DLG1; disks large homolog 1 isoform 1; K12076 disks large protein 1 (A)	Hippo signaling pathway (ko04390);; T cell receptor signaling pathway (ko04660);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[F]	Nucleotide transport and metabolism	Guanylate kinase;; PDZ domain (Also known as DHR or GLGF);; Polyubiquitination (PEST) N-terminal domain of MAGUK;; L27_1;; PDZ-associated domain of NMDA receptors;; PDZ domain;; SH3 domain;; Variant SH3 domain	Disks large homolog 1 GN=DLG1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: disks large homolog 1 isoformX5 [Canis lupus familiaris]
ENSG00000075785(RAB7A)	--	91.859586	3502	101.577079	3746	92.58098621	3528	101.302283	4088	98.329232	3763	98.55198508	4006	0.982623573	0.192305704	normal	0.991472924	-0.014888171	normal	0.98463353	0.174949999	normal	0.589171473	0.116571462	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07897|9.69359e-153|umr:103669493|RAB7A; RAB7A, member RAS oncogene family; K07897 Ras-related protein Rab-7A (A)"	Endocytosis (ko04144);; Phagosome (ko04145);; Salmonella infection (ko05132);; Amoebiasis (ko05146);; Tuberculosis (ko05152)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-7a GN=RAB7A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-7a [Balaenoptera acutorostrata scammoni]
ENSG00000075790(BCAP29)	--	18.64594301	724	25.67138028	867	22.75480925	808	23.41916585	935	18.23299591	718	19.84016054	767	0.850868032	0.33751271	normal	0.904284122	-0.292912321	normal	0.973915826	-0.083260192	normal	0.984925516	-0.009338833	normal	--	--	Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: intracellular protein transport (GO:0006886);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[V]	Defense mechanisms	B-cell receptor-associated protein 31-like	B-cell receptor-associated protein 29 GN=BCAP29 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: B-cell receptor-associated protein 29 [Trichechus manatus latirostris]
ENSG00000075826(SEC31B)	--	1.44305	129	1.35259	121	1.43652	128	1.27077	112	1.72902	153	2.02882	181	0.951779601	-0.231739324	normal	0.921854433	0.313605654	normal	0.738080682	0.48669593	normal	0.623059952	0.218968034	normal	[R]	General function prediction only	--	"K14005|0|hsa:25956|SEC31B, SEC31B-1, SEC31L2; SEC31 homolog B (S. cerevisiae); K14005 protein transport protein SEC31 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"WD domain, G-beta repeat;; Sec23-binding domain of Sec16"	Protein transport protein Sec31B GN=SEC31B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec31B [Camelus ferus]
ENSG00000075856(SART3)	--	18.996445	1472	20.797217	1666	21.52992369	1713	20.46541979	1692	20.44243699	1615	19.93824878	1606	0.973266712	0.169954083	normal	0.983280852	-0.066219738	normal	0.981862512	-0.101252364	normal	0.996314771	-0.002899113	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Lsm interaction motif"	Squamous cell carcinoma antigen recognized by T-cells 3 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: squamous cell carcinoma antigen recognized by T-cells 3 isoform X2 [Pteropus alecto]
ENSG00000075884(ARHGAP15)	--	0.0284849	1	0.0866215	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; PH domain	Rho GTPase-activating protein 15 GN=ARHGAP15 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 15 [Ceratotherium simum simum]
ENSG00000075886(TUBA3D)	--	0.340231	10	0.405095	12	0.296195	8	0.134946	4	0.330101	9	0.234413	7	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	K07374|0|dpe:Dper_GL12416|GL12416 gene product from transcript GL12416-RA; K07374 tubulin alpha (A)	Phagosome (ko04145)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha-3C/D chain GN=TUBA3D OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	Tubulin alpha-3 chain [Myotis davidii]
ENSG00000075891(PAX2)	--	0.226390724	15	0.017156634	1	0.107550308	7	0.091910668	6	0.058265808	3	0.016859824	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K15608|0|ssc:100515585|PAX2; paired box 2; K15608 paired box protein 2 (A)	--	[K]	Transcription	'Paired box' domain;; Paired-box protein 2 C terminal	Paired box protein Pax-2 GN=PAX2 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: paired box protein Pax-2 isoformX2 [Sus scrofa] 
ENSG00000075914(EXOSC7)	--	17.12739	338	15.96473	323	15.42665	329	19.45233	387	20.93608	393	17.74621	351	0.954819506	0.163781931	normal	0.920741323	0.260461561	normal	0.96534477	0.08471495	normal	0.561944069	0.170655222	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K12589|0|hsa:23016|EXOSC7, EAP1, RRP42, Rrp42p, hRrp42p, p8; exosome component 7 (EC:3.1.13.-); K12589 exosome complex component RRP42 (A)"	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	"3' exoribonuclease family, domain 1;; 3' exoribonuclease family, domain 2"	Exosome complex component RRP42 GN=EXOSC7 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component RRP42 [Felis catus]
ENSG00000075945(KIFAP3)	--	7.7601434	398	7.176818797	371	7.447124	375	9.8116415	502	8.890603258	457	7.150334131	368	0.889043907	0.303043125	normal	0.909407258	0.278324649	normal	0.968668621	-0.035332432	normal	0.469660605	0.191965861	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Kinesin-associated protein (KAP);; Armadillo/beta-catenin-like repeat	Kinesin-associated protein 3 GN=KIFAP3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: kinesin-associated protein 3 isoform X2 [Ailuropoda melanoleuca]
ENSG00000075975(MKRN2)	--	12.429938	605	12.103692	617	10.52725993	525	12.69447671	644	12.3898938	617	10.41827723	527	0.972564216	0.059147686	normal	0.973170818	-0.02137417	normal	0.972353544	-0.002797859	normal	0.97799303	0.01144033	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	K15687|0|ptr:460180|MKRN2; makorin ring finger protein 2; K15687 E3 ubiquitin-protein ligase makorin [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Zinc finger C-x8-C-x5-C-x3-H type;; Zinc finger, C3HC4 type (RING finger)"	Probable E3 ubiquitin-protein ligase makorin-2 GN=MKRN2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase makorin-2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000076003(MCM6)	--	48.970753	3257	45.16238	3033	50.5158083	3347	29.598102	1990	30.392257	2015	19.50483101	1299	0.001493486	-0.741155341	normal	0.056950901	-0.61101565	normal	1.47E-14	-1.37272498	down	2.43E-08	-0.88365105	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; Molecular Function: ATPase activity (GO:0016887);; 	K02542|0|pps:100995909|MCM6; minichromosome maintenance complex component 6; K02542 DNA replication licensing factor MCM6 [EC:3.6.4.12] (A)	DNA replication (ko03030);; Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; MCM N-terminal domain;; Magnesium chelatase, subunit ChlI;; ATPase family associated with various cellular activities (AAA)"	DNA replication licensing factor MCM6 GN=MCM6 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA replication licensing factor MCM6 [Equus caballus] 
ENSG00000076043(REXO2)	--	67.5629484	1340	50.3048688	1021	61.18664	1236	47.767699	964	44.948835	873	43.140372	853	0.308216279	-0.505273689	normal	0.939110951	-0.246959806	normal	0.182111254	-0.542548746	normal	0.008730378	-0.440631878	normal	[A]	RNA processing and modification	--	K13288|1.61676e-132|pon:100448595|REXO2; RNA exonuclease 2; K13288 oligoribonuclease [EC:3.1.-.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	Exonuclease	"Oligoribonuclease, mitochondrial (Precursor) GN=REXO2 OS=Homo sapiens (Human) PE=1 SV=3"	L	"Replication, recombination and repair"	"PREDICTED: oligoribonuclease, mitochondrial isoform X2 [Oryctolagus cuniculus]"
ENSG00000076053(RBM7)	--	21.04245863	756	14.84610201	506	20.24450699	738	15.62120522	583	18.88194206	647	17.19673666	629	0.704289628	-0.404782778	normal	0.857484211	0.332321504	normal	0.936975812	-0.238322653	normal	0.721269742	-0.126032083	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13188|1.50944e-175|hsa:10179|RBM7; RNA binding motif protein 7; K13188 RNA-binding protein 7 (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 7 GN=RBM7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RNA-binding protein 7 isoform 1 [Dasypus novemcinctus]
ENSG00000076067(RBMS2)	--	9.119224	1024	10.693646	1122	10.97115828	1153	12.92478675	1746	9.668697523	1321	13.314904	1575	0.00197496	0.738148147	normal	0.957978693	0.213865336	normal	0.587892712	0.441170852	normal	0.004686425	0.471197725	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"RNA-binding motif, single-stranded-interacting protein 2 GN=RBMS2 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: RNA-binding motif, single-stranded-interacting protein 2 isoform X1 [Galeopterus variegatus] "
ENSG00000076108(BAZ2A)	--	19.40784284	3293	18.88331906	3266	21.99445013	3581	21.733712	3345	20.825644	3470	21.05892525	3358	0.990946051	-0.008224757	normal	0.989949734	0.065954684	normal	0.989219458	-0.101007672	normal	0.959389613	-0.016306604	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	"K15224|0|hsa:11176|BAZ2A, TIP5, WALp3; bromodomain adjacent to zinc finger domain, 2A; K15224 bromodomain adjacent to zinc finger domain protein 2A (A)"	--	[B]	Chromatin structure and dynamics	"Bromodomain;; Methyl-CpG binding domain;; DDT domain;; PHD-finger;; WSTF, HB1, Itc1p, MBD9 motif 3;; WSTF, HB1, Itc1p, MBD9 motif 1"	Bromodomain adjacent to zinc finger domain protein 2A GN=BAZ2A OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: bromodomain adjacent to zinc finger domain protein 2A isoform X1 [Equus przewalskii]
ENSG00000076201(PTPN23)	--	11.12905	1223	11.7687603	1289	11.377072	1272	10.568851	1149	9.903554	1069	13.7053679	1508	0.975805113	-0.12072136	normal	0.916745923	-0.291041392	normal	0.952484634	0.236987255	normal	0.903212386	-0.042678263	normal	--	--	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18040|0|hsa:25930|PTPN23, HD-PTP, HDPTP, PTP-TD14; protein tyrosine phosphatase, non-receptor type 23 (EC:3.1.3.48); K18040 tyrosine-protein phosphatase non-receptor type 23 [EC:3.1.3.48] (A)"	--	[R]	General function prediction only	BRO1-like domain;; Protein-tyrosine phosphatase;; ALIX V-shaped domain binding to HIV	Tyrosine-protein phosphatase non-receptor type 23 GN=PTPN23 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 23 isoform X1 [Galeopterus variegatus]
ENSG00000076242(MLH1)	--	22.90755471	1211	20.3966231	1047	22.93491535	1135	20.8998966	1075	19.67127359	1010	21.56064397	1046	0.960138791	-0.202421672	normal	0.977389231	-0.073225012	normal	0.974129806	-0.125926055	normal	0.525197722	-0.137191551	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	"K08734|0|hsa:4292|MLH1, COCA2, FCC2, HNPCC, HNPCC2, hMLH1; mutL homolog 1; K08734 DNA mismatch repair protein MLH1 (A)"	Mismatch repair (ko03430);; Fanconi anemia pathway (ko03460);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213)	[L]	"Replication, recombination and repair"	"DNA mismatch repair protein, C-terminal domain;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	DNA mismatch repair protein Mlh1 GN=MLH1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA mismatch repair protein Mlh1 isoform X1 [Galeopterus variegatus] 
ENSG00000076248(UNG)	--	45.6445	1579	49.6811	1742	47.9245	1668	54.6495	1903	56.5224	1946	37.57047	1299	0.957232921	0.238220747	normal	0.979581905	0.138226952	normal	0.817488332	-0.368629547	normal	0.95908328	0.023088558	normal	[L]	"Replication, recombination and repair"	--	K03648|0|ptr:452217|UNG; uracil-DNA glycosylase; K03648 uracil-DNA glycosylase [EC:3.2.2.27] (A)	Base excision repair (ko03410);; Primary immunodeficiency (ko05340)	[L]	"Replication, recombination and repair"	Uracil DNA glycosylase superfamily	Uracil-DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_03166} OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: uracil-DNA glycosylase [Pteropus alecto] 
ENSG00000076258(FMO4)	--	0.69257	27	0.462883	18	0.588962	22	0.433534	17	0.54994	21	0.280257	11	0.966698487	-0.651164872	normal	0.987400218	0.186453189	normal	0.952638662	-0.917593066	normal	0.584775034	-0.473428825	normal	[P]	Inorganic ion transport and metabolism	"Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00485|0|hsa:2329|FMO4, FMO2; flavin containing monooxygenase 4 (EC:1.14.13.8); K00485 dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] (A)"	Drug metabolism - cytochrome P450 (ko00982)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; L-lysine 6-monooxygenase (NADPH-requiring);; Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain;; FAD-NAD(P)-binding	Dimethylaniline monooxygenase [N-oxide-forming] 4 GN=FMO4 OS=Homo sapiens (Human) PE=2 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: dimethylaniline monooxygenase [N-oxide-forming] 4 [Balaenoptera acutorostrata scammoni]
ENSG00000076321(KLHL20)	--	5.546781072	348	5.609974437	350	5.237378451	321	6.423352978	399	6.43171	395	6.102535897	383	0.954550666	0.165785248	normal	0.956346137	0.152450844	normal	0.929086161	0.245419876	normal	0.509562734	0.186507407	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10457|0|umr:103668215|KLHL20; kelch-like family member 20; K10457 kelch-like protein 20 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; BTB/POZ domain;; Kelch motif;; Kelch motif"	Kelch-like protein 20 GN=KLHL20 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 20 [Tupaia chinensis]
ENSG00000076344(RGS11)	--	0.956249248	46	1.159650941	57	1.010124811	49	1.24114753	60	1.45305391	70	1.14984	56	0.961744694	0.342457783	normal	0.962283075	0.26852841	normal	0.974486096	0.179177529	normal	0.678753436	0.269812059	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Cellular Component: heterotrimeric G-protein complex (GO:0005834);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Biological Process: intracellular signal transduction (GO:0035556);; 	K16449|0|ggo:101147688|RGS11; regulator of G-protein signaling 11 isoform 1; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	"Regulator of G protein signaling domain;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; GGL domain"	Regulator of G-protein signaling 11 GN=RGS11 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 11 [Pteropus alecto]
ENSG00000076351(SLC46A1)	--	15.30238041	1908	15.78958457	1885	14.62437582	1836	14.03350948	1539	16.36240257	1655	13.48589016	1631	0.874763258	-0.34059412	normal	0.966947846	-0.208980781	normal	0.973234192	-0.178944236	normal	0.159675972	-0.243392974	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14613|0|ptr:454527|SLC46A1; solute carrier family 46 (folate transporter), member 1; K14613 MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3 (A)"	--	[R]	General function prediction only	Major Facilitator Superfamily	Proton-coupled folate transporter GN=SLC46A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: proton-coupled folate transporter isoform X1 [Mustela putorius furo] 
ENSG00000076356(PLXNA2)	--	0.384791683	66	0.226896319	34	0.343792158	53	1.085093184	185	1.145664733	196	0.883821	128	1.64E-06	1.435364366	up	4.44E-16	2.454663876	up	0.000952837	1.240307578	up	9.09E-07	1.712275487	up	--	--	Molecular Function: protein binding (GO:0005515);; 	K06820|0|pps:100976998|PLXNA2; plexin A2; K06820 plexin A (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; Sema domain;; IPT/TIG domain;; Plexin repeat	Plexin-A2 (Precursor) GN=PLXNA2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: plexin-A2 [Equus caballus]
ENSG00000076382(SPAG5)	--	30.23408067	2443	32.33711353	2419	32.90170359	2546	26.22380556	1990	26.1486728	1961	27.40364847	1952	0.905592825	-0.32648971	normal	0.910771566	-0.32402234	normal	0.793158153	-0.391304546	normal	0.025914722	-0.348796478	normal	--	--	--	--	--	--	--	--	Sperm-associated antigen 5 GN=SPAG5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: sperm-associated antigen 5 [Equus caballus]
ENSG00000076513(ANKRD13A)	--	6.651342649	516	5.447696084	409	5.5368534	431	9.954146707	756	9.1389463	714	8.07480302	630	0.293853003	0.518899576	normal	0.002486312	0.780186685	normal	0.25427476	0.537802666	normal	0.000418185	0.609237386	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	GPCR-chaperone;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 13A GN=ANKRD13A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 13A [Ceratotherium simum simum]
ENSG00000076554(TPD52)	--	43.82775127	2058	42.39904008	1933	49.46025648	2252	45.11832558	2109	36.22874917	1749	36.99722199	1686	0.987244429	0.004480545	normal	0.976135598	-0.165601631	normal	0.674783152	-0.425562254	normal	0.296611368	-0.193003148	normal	--	--	--	--	--	[R]	General function prediction only	Tumour protein D52 family	Tumor protein D52 GN=TPD52 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: tumor protein D52 isoform X1 [Galeopterus variegatus]
ENSG00000076555(ACACB)	--	3.964335402	814	3.475746432	694	4.696735938	780	2.813391439	560	4.364702828	666	3.479153505	671	0.135627757	-0.569130703	normal	0.971652087	-0.080660601	normal	0.943906919	-0.224982026	normal	0.13134065	-0.290881905	normal	[I]	Lipid transport and metabolism	Molecular Function: acetyl-CoA carboxylase activity (GO:0003989);; Molecular Function: ATP binding (GO:0005524);; Biological Process: fatty acid biosynthetic process (GO:0006633);; 	"K11262|0|hsa:32|ACACB, ACC2, ACCB, HACC275; acetyl-CoA carboxylase beta (EC:6.4.1.2 6.3.4.14); K11262 acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14] (A)"	Fatty acid biosynthesis (ko00061);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640);; Fatty acid metabolism (ko01212);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	"Acetyl-CoA carboxylase, central region;; Carboxyl transferase domain;; Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; Biotin-requiring enzyme;; ATP-grasp domain"	Biotin carboxylase (Precursor) GN=ACACB OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: acetyl-CoA carboxylase 2 [Galeopterus variegatus]
ENSG00000076604(TRAF4)	--	24.76886	1106	28.858088	1363	26.481621	1243	24.485016	1160	25.488785	1164	30.15420106	1378	0.980469182	0.03788976	normal	0.945184665	-0.248821955	normal	0.974948384	0.140295973	normal	0.93492335	-0.024610326	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K09848|0|hsa:9618|TRAF4, CART1, MLN62, RNF83; TNF receptor-associated factor 4; K09848 TNF receptor-associated factor 4 (A)"	Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	"TRAF-type zinc finger;; MATH domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc-finger of the MIZ type in Nse subunit"	TNF receptor-associated factor 4 GN=TRAF4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TNF receptor-associated factor 4 [Ceratotherium simum simum]
ENSG00000076641(PAG1)	--	0.470223072	84	0.5157449	92	0.437406257	78	0.56744734	102	0.344717597	62	0.616006758	111	0.956488758	0.245200851	normal	0.801082247	-0.579118424	normal	0.846741498	0.492675962	normal	0.892283724	0.093245754	normal	--	--	Cellular Component: plasma membrane (GO:0005886);; Biological Process: intracellular signal transduction (GO:0035556);; Cellular Component: membrane raft (GO:0045121);; Biological Process: negative regulation of T cell activation (GO:0050868);; 	--	--	--	--	Phosphoprotein associated with glycosphingolipid-enriched	Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 GN=PAG1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: phosphoprotein associated with glycosphingolipid-enriched microdomains 1 isoform X1 [Equus caballus] 
ENSG00000076650(GPATCH1)	--	6.14259	524	6.32891	537	6.81179	576	5.93191	509	6.43599	546	6.48995	557	0.969672208	-0.072517661	normal	0.971898509	0.002545197	normal	0.971728029	-0.056531982	normal	0.898038535	-0.042957951	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: mRNA processing (GO:0006397);; 	"K13123|0|hsa:55094|GPATCH1, ECGP, GPATC1; G patch domain containing 1; K13123 G patch domain-containing protein 1 (A)"	--	[A]	RNA processing and modification	Protein of unknown function (DUF1604);; G-patch domain	G patch domain-containing protein 1 GN=GPATCH1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: G patch domain-containing protein 1 isoform X1 [Ailuropoda melanoleuca]
ENSG00000076662(ICAM3)	--	1.527107536	51	2.149731876	41	1.629379503	51	2.024542931	57	2.413326035	79	2.153044198	61	0.976402042	0.126039677	normal	0.355163024	0.90048485	normal	0.969389363	0.243412991	normal	0.430616503	0.441565353	normal	--	--	--	"K06486|0|hsa:3385|ICAM3, CD50, CDW50, ICAM-R; intercellular adhesion molecule 3; K06486 intercellular adhesion molecule 3 (A)"	Cell adhesion molecules (CAMs) (ko04514)	--	--	"Intercellular adhesion molecule (ICAM), N-terminal domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain"	Intercellular adhesion molecule 3 (Precursor) GN=ICAM3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: intercellular adhesion molecule 3 [Ursus maritimus] 
ENSG00000076685(NT5C2)	--	53.87606275	3214	70.98687485	4437	62.71213584	3632	49.50249657	2888	47.816892	2890	60.86701479	3761	0.980776697	-0.185038073	normal	0.032797497	-0.639669262	normal	0.991349836	0.042043458	normal	0.390690789	-0.262814959	normal	--	--	--	"K01081|0|nle:100598503|NT5C2; 5'-nucleotidase, cytosolic II; K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	[F]	Nucleotide transport and metabolism	5' nucleotidase family	Cytosolic purine 5'-nucleotidase GN=NT5C2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: cytosolic purine 5'-nucleotidase isoform X1 [Condylura cristata]
ENSG00000076706(MCAM)	--	6.699801	499	5.538788	416	5.768577	436	11.63624	863	13.06143	968	6.156157	461	0.002482142	0.757694077	normal	4.62E-09	1.194069478	up	0.968436183	0.071904601	normal	0.152071336	0.739938946	normal	--	--	--	"K06534|0|hsa:4162|MCAM, CD146, MUC18; melanoma cell adhesion molecule; K06534 melanoma cell adhesion molecule (A)"	--	--	--	Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain	Cell surface glycoprotein MUC18 (Precursor) GN=MCAM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cell surface glycoprotein MUC18 [Ceratotherium simum simum]
ENSG00000076716(GPC4)	--	0.0248817	2	0.0123811	1	0	0	0.0123433	1	0.03612	2	0.0123292	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Cellular Component: membrane (GO:0016020);; Molecular Function: heparan sulfate proteoglycan binding (GO:0043395);; 	K08110|0|ptr:473788|GPC4; glypican 4; K08110 glypican 4 (K-glypican) (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Glypican	Secreted glypican-4 (Precursor) GN=GPC4 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: glypican-4 [Vicugna pacos]
ENSG00000076770(MBNL3)	--	0	0	0.023370646	3	0.015603044	1	0.079009137	5	0.085677694	4	0.092624886	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K14943|0|ptr:741399|MBNL3; muscleblind-like splicing regulator 3; K14943 muscleblind (A)	--	[K]	Transcription	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Muscleblind-like protein 3 GN=MBNL3 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: muscleblind-like protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000076826(CAMSAP3)	--	1.690724475	135	0.965999324	78	1.213155217	103	2.599213547	212	2.522123185	205	1.765532673	146	0.35779162	0.614648232	normal	3.31E-06	1.355833529	up	0.790043031	0.488973607	normal	0.013036956	0.811073921	normal	--	--	Molecular Function: calmodulin binding (GO:0005516);; Molecular Function: microtubule binding (GO:0008017);; Molecular Function: spectrin binding (GO:0030507);; Biological Process: neuron projection development (GO:0031175);; 	"K17493|0|hsa:57662|CAMSAP3, KIAA1543, NEZHA, PPP1R80; calmodulin regulated spectrin-associated protein family, member 3; K17493 calmodulin-regulated spectrin-associated protein (A)"	--	[Z]	Cytoskeleton	Microtubule-binding calmodulin-regulated spectrin-associated;; CAMSAP CH domain;; Calponin homology (CH) domain	Calmodulin-regulated spectrin-associated protein 3 GN=CAMSAP3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: calmodulin-regulated spectrin-associated protein 3 [Sorex araneus]
ENSG00000076864(RAP1GAP)	--	2.929803973	223	4.536919123	341	3.50590145	272	2.793847829	209	4.452900673	333	3.210852651	243	0.96066657	-0.123493898	normal	0.966210685	-0.055427363	normal	0.953335551	-0.169941559	normal	0.845964132	-0.111547528	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: GTPase regulator activity (GO:0030695);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	K17700|0|mcf:101925108|uncharacterized LOC101925108; K17700 RAP1 GTPase activating protein 1 (A)	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Rap/ran-GAP;; GoLoco motif	Rap1 GTPase-activating protein 1 GN=RAP1GAP OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: RAP1 GTPase activating protein [Vicugna pacos]
ENSG00000076924(XAB2)	--	13.6319	698	14.0224	728	13.4328	707	13.5166	697	13.3299	683	13.2865	685	0.974904169	-0.032828331	normal	0.969081522	-0.11323652	normal	0.974202423	-0.053780792	normal	0.813067828	-0.068009765	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12867|0|ptr:468695|XAB2; XPA binding protein 2; K12867 pre-mRNA-splicing factor SYF1 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Suppressor of forked protein (Suf);; Tetratricopeptide repeat;; Tetratricopeptide repeat	Pre-mRNA-splicing factor SYF1 GN=XAB2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: pre-mRNA-splicing factor SYF1 [Oryctolagus cuniculus]
ENSG00000076928(ARHGEF1)	--	38.15924599	2510	35.77748588	2345	38.3031597	2609	40.36295489	2799	41.63072294	2884	37.52368046	2444	0.985261061	0.126318616	normal	0.951733597	0.27689542	normal	0.986315342	-0.102482713	normal	0.644898484	0.101381591	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K12330|0|mcf:102143411|ARHGEF1; Rho guanine nucleotide exchange factor (GEF) 1; K12330 Rho guanine nucleotide exchange factor 1 (A)	Vascular smooth muscle contraction (ko04270);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Regulator of G protein signalling-like domain;; RhoGEF domain	Rho guanine nucleotide exchange factor 1 GN=ARHGEF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 1 isoform X4 [Tupaia chinensis]
ENSG00000076944(STXBP2)	--	23.48445074	876	21.33410873	819	22.47027883	848	16.01324924	584	18.38424128	697	17.04954114	655	0.0568921	-0.614464866	normal	0.930867573	-0.253623062	normal	0.76882236	-0.380087313	normal	0.016356831	-0.414226022	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K15300|0|mcf:101866424|uncharacterized LOC101866424; K15300 syntaxin-binding protein 2 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec1 family	Syntaxin-binding protein 2 GN=STXBP2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-binding protein 2 isoform 1 [Orcinus orca] 
ENSG00000076984(MAP2K7)	--	7.595562	510	8.685409	597	8.08056	558	7.47068	500	8.250324	551	8.61638	582	0.970258393	-0.059221222	normal	0.963258629	-0.136744482	normal	0.971999307	0.052323729	normal	0.883338667	-0.048730985	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04431|0|hsa:5609|MAP2K7, JNKK2, MAPKK7, MEK, MEK_7, MKK7, PRKMK7, SAPKK-4, SAPKK4; mitogen-activated protein kinase kinase 7 (EC:2.7.12.2); K04431 mitogen-activated protein kinase kinase 7 [EC:2.7.12.2] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Protein processing in endoplasmic reticulum (ko04141);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; GnRH signaling pathway (ko04912);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Dual specificity mitogen-activated protein kinase kinase 7 GN=MAP2K7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity mitogen-activated protein kinase kinase 7 isoform X2 [Bubalus bubalis] 
ENSG00000077044(DGKD)	--	15.32346299	1947	16.12240248	2130	15.97000654	2113	24.32802722	3141	24.13428727	3070	27.46572889	3429	0.014870927	0.65872598	normal	0.374853547	0.5056581	normal	0.006613916	0.68981244	normal	1.10E-05	0.618195706	normal	[T]	Signal transduction mechanisms	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|ptr:460025|DGKD; diacylglycerol kinase, delta 130kDa; K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; SAM domain (Sterile alpha motif);; Phorbol esters/diacylglycerol binding domain (C1 domain);; SAM domain (Sterile alpha motif);; PH domain;; PH domain	Diacylglycerol kinase delta GN=DGKD OS=Homo sapiens (Human) PE=1 SV=4	I	Lipid transport and metabolism	PREDICTED: diacylglycerol kinase delta [Odobenus rosmarus divergens]
ENSG00000077063(CTTNBP2)	--	1.913298342	168	1.396279061	179	1.501629315	169	1.02117335	106	1.830521885	136	1.060234908	119	0.276826272	-0.687241894	normal	0.838888037	-0.413755492	normal	0.71552766	-0.508898101	normal	0.101239674	-0.536189809	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Cortactin-binding protein-2;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Cortactin-binding protein 2 GN=CTTNBP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cortactin-binding protein 2 [Ceratotherium simum simum]
ENSG00000077092(RARB)	--	3.70901	212	3.30103413	182	2.81388	158	3.504238	198	5.115695711	287	3.866287	214	0.960295421	-0.128432667	normal	0.19917139	0.631473973	normal	0.80015498	0.425879517	normal	0.349383909	0.319477353	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08528|0|ptr:745516|RARB; retinoic acid receptor, beta; K08528 retinoic acid receptor beta (A)"	Pathways in cancer (ko05200);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Retinoic acid receptor beta GN=RARB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: retinoic acid receptor beta isoform X2 [Tupaia chinensis]
ENSG00000077097(TOP2B)	--	43.31888039	4633	41.40476305	4521	45.667584	4945	40.726826	4477	43.24115964	4688	37.00380009	4009	0.991929187	-0.080219562	normal	0.99260698	0.030893946	normal	0.9487778	-0.310913739	normal	0.584765421	-0.119214042	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase type II (ATP-hydrolyzing) activity (GO:0003918);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA topological change (GO:0006265);; 	K03164|0|ptr:460232|TOP2B; topoisomerase (DNA) II beta 180kDa; K03164 DNA topoisomerase II [EC:5.99.1.3] (A)	--	[B]	Chromatin structure and dynamics	"DNA gyrase/topoisomerase IV, subunit A;; DNA gyrase B;; DTHCT (NUC029) region;; Toprim domain;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	DNA topoisomerase 2-beta GN=TOP2B OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: DNA topoisomerase 2-beta [Ailuropoda melanoleuca]
ENSG00000077147(TM9SF3)	--	71.95746852	5491	73.53122258	5643	72.7703576	5020	82.70803889	6535	77.43748828	6015	84.62720858	6334	0.984449398	0.220229522	normal	0.993335246	0.070657488	normal	0.946670528	0.327050162	normal	0.28589092	0.203769922	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17087|0|ptr:450645|TM9SF3, SMBP; transmembrane 9 superfamily member 3; K17087 transmembrane 9 superfamily member 3 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endomembrane protein 70	Transmembrane 9 superfamily member 3 (Precursor) GN=TM9SF3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane 9 superfamily member 3 [Odobenus rosmarus divergens]
ENSG00000077150(NFKB2)	--	37.69700936	1654	31.22903902	1531	39.14003423	1902	26.66650622	1174	23.88716898	1097	39.2101721	1800	0.234398947	-0.524777299	normal	0.34874682	-0.501748871	normal	0.983934357	-0.087740059	normal	0.344177134	-0.341008573	normal	[R]	General function prediction only	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K04469|0|hsa:4791|NFKB2, CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p52; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); K04469 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (A)"	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Osteoclast differentiation (ko04380);; Legionellosis (ko05134);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203)	--	--	Rel homology domain (RHD);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Death domain	Nuclear factor NF-kappa-B p52 subunit GN=NFKB2 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: nuclear factor NF-kappa-B p100 subunit isoform X1 [Galeopterus variegatus]
ENSG00000077152(UBE2T)	--	59.7217	829	56.9661	786	60.9129	844	49.5684	702	47.3447	651	37.6992	528	0.920106943	-0.270188384	normal	0.902509725	-0.29267852	normal	0.014228182	-0.683433744	normal	0.019799319	-0.408485351	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K13960|8.47137e-145|pps:100972197|UBE2T; ubiquitin-conjugating enzyme E2T (putative); K13960 ubiquitin-conjugating enzyme E2 T [EC:6.3.2.19] (A)	Fanconi anemia pathway (ko03460)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 T GN=UBE2T OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 T [Tupaia chinensis]
ENSG00000077157(PPP1R12B)	--	2.461498868	628	2.099431583	635	3.110137088	796	2.057748217	534	2.019720358	531	2.852603346	667	0.920025392	-0.26405554	normal	0.910545879	-0.278744229	normal	0.924521842	-0.262826871	normal	0.256042157	-0.26961877	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: protein kinase binding (GO:0019901);; 	"K12329|0|mcf:102121021|PPP1R12B; protein phosphatase 1, regulatory subunit 12B; K12329 protein phosphatase 1 regulatory subunit 12B (A)"	Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Proteoglycans in cancer (ko05205)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Protein phosphatase 1 regulatory subunit 12B GN=PPP1R12B OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: protein phosphatase 1 regulatory subunit 12B isoform X5 [Canis lupus familiaris]
ENSG00000077232(DNAJC10)	--	54.64096983	3965	53.6996909	3843	51.24859139	3733	37.62883235	2831	32.55656618	2431	34.14481066	2586	0.320155058	-0.516603211	normal	0.010714514	-0.681769181	normal	0.226215307	-0.537641472	normal	5.29E-05	-0.577967747	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell redox homeostasis (GO:0045454);; 	K09530|0|ggo:101140979|DNAJC10; dnaJ homolog subfamily C member 10 isoform 1; K09530 DnaJ homolog subfamily C member 10 (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; DnaJ domain;; Thioredoxin-like;; Thioredoxin-like domain;; Thioredoxin-like domain;; Thioredoxin-like;; Redoxin;; AhpC/TSA family	DnaJ homolog subfamily C member 10 (Precursor) GN=DNAJC10 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: dnaJ homolog subfamily C member 10-like [Tupaia chinensis]
ENSG00000077235(GTF3C1)	--	22.97322082	3765	22.15231748	3737	24.01617382	3965	21.72928094	3626	23.11741307	3811	21.87821441	3517	0.990349175	-0.085067825	normal	0.991535332	0.006859738	normal	0.983847503	-0.181193546	normal	0.709106598	-0.08717162	normal	--	--	--	"K15199|0|pps:100971391|GTF3C1; general transcription factor IIIC, polypeptide 1, alpha 220kDa; K15199 general transcription factor 3C polypeptide 1 (A)"	--	[K]	Transcription	B-block binding subunit of TFIIIC	General transcription factor 3C polypeptide 1 GN=GTF3C1 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: general transcription factor 3C polypeptide 1 [Pteropus alecto]
ENSG00000077238(IL4R)	--	11.21612034	803	6.979681831	529	7.701246	595	12.29505375	957	14.09619172	965	10.51816701	761	0.948387154	0.221897388	normal	0.00028477	0.844022648	normal	0.835548358	0.34593602	normal	0.086433407	0.455586853	normal	--	--	Biological Process: production of molecular mediator involved in inflammatory response (GO:0002532);; Molecular Function: cytokine receptor activity (GO:0004896);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05071|0|hsa:3566|IL4R, CD124, IL-4RA, IL4RA; interleukin 4 receptor; K05071 interleukin 4 receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Inflammatory bowel disease (IBD) (ko05321)	--	--	"Interleukin-4 receptor alpha chain, N-terminal"	Soluble interleukin-4 receptor subunit alpha (Precursor) GN=IL4R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-4 receptor subunit alpha [Galeopterus variegatus]
ENSG00000077254(USP33)	--	11.14137472	791	10.243024	742	10.64032137	726	11.918703	839	10.74088601	782	11.40711206	844	0.975967309	0.054058893	normal	0.974627726	0.054215225	normal	0.951388845	0.208578696	normal	0.675239963	0.104618766	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11848|0|hsa:23032|USP33, VDU1; ubiquitin specific peptidase 33 (EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; DUSP domain;; Zn-finger in ubiquitin-hydrolases and other protein	Ubiquitin carboxyl-terminal hydrolase 33 GN=USP33 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"Ubiquitin carboxyl-terminal hydrolase 33, partial [Bos mutus]"
ENSG00000077264(PAK3)	--	0.360775046	34	0.335421572	31	0.540627241	46	2.162599268	200	1.865591993	168	1.508995885	140	1.11E-16	2.473620246	up	1.08E-13	2.361500203	up	2.79E-06	1.566439555	up	1.06E-11	2.172665435	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05733|0|phd:102330386|PAK3; p21 protein (Cdc42/Rac)-activated kinase 3; K05733 p21-activated kinase 3 [EC:2.7.11.1] (A)	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Axon guidance (ko04360);; Focal adhesion (ko04510);; T cell receptor signaling pathway (ko04660);; Regulation of actin cytoskeleton (ko04810);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; P21-Rho-binding domain;; Kinase-like	Serine/threonine-protein kinase PAK 3 GN=PAK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	serine/threonine-protein kinase PAK 3 [Bos taurus] 
ENSG00000077312(SNRPA)	--	61.00787	1505	60.31643875	1450	62.977607	1560	58.65483655	1487	57.71828	1416	58.76291115	1497	0.9832993	-0.048141658	normal	0.982189246	-0.055599511	normal	0.982838318	-0.067696251	normal	0.820323892	-0.058306214	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K11091|1.38861e-130|hsa:6626|SNRPA, Mud1, U1-A, U1A; small nuclear ribonucleoprotein polypeptide A; K11091 U1 small nuclear ribonucleoprotein A (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	U1 small nuclear ribonucleoprotein A GN=SNRPA OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: U1 small nuclear ribonucleoprotein A [Chrysochloris asiatica]
ENSG00000077327(SPAG6)	--	0.101395289	4	0	0	0.098120961	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT repeat;; HEAT-like repeat;; DNA alkylation repair enzyme;; non-SMC mitotic condensation complex subunit 1;; Proteasome non-ATPase 26S subunit;; Adaptin N terminal region	Sperm-associated antigen 6 GN=SPAG6 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sperm-associated antigen 6 isoform X1 [Tupaia chinensis]
ENSG00000077348(EXOSC5)	--	38.548998	711	42.41934	803	45.934255	876	40.675028	759	34.371614	629	34.48582	635	0.974257116	0.063285693	normal	0.790431339	-0.372970693	normal	0.463289828	-0.471505409	normal	0.180114667	-0.262067951	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K12590|4.10096e-146|hsa:56915|EXOSC5, RRP41B, RRP46, Rrp46p, hRrp46p, p12B; exosome component 5; K12590 exosome complex component RRP46 (A)"	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	"3' exoribonuclease family, domain 1;; 3' exoribonuclease family, domain 2"	Exosome complex component RRP46 GN=EXOSC5 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component RRP46 [Equus caballus]
ENSG00000077380(DYNC1I2)	--	41.41929586	2112	41.87110435	2104	45.3766836	2276	31.60863683	1614	31.96892339	1597	26.71921429	1350	0.694182461	-0.418452081	normal	0.708674312	-0.418850188	normal	0.000902211	-0.761168259	normal	0.000227204	-0.530850699	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasmic dynein complex (GO:0005868);; Biological Process: microtubule-based movement (GO:0007018);; 	"K10415|0|pon:100174119|DYNC1I2; dynein, cytoplasmic 1, intermediate chain 2; K10415 dynein intermediate chain, cytosolic (A)"	Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Cytoplasmic dynein 1 intermediate chain 2;; WD domain, G-beta repeat"	Cytoplasmic dynein 1 intermediate chain 2 GN=DYNC1I2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: cytoplasmic dynein 1 intermediate chain 2 isoform X1 [Mustela putorius furo]
ENSG00000077420(APBB1IP)	--	0.365878	20	0.680732992	37	0.3602036	19	6.758558	368	5.646867	311	7.98776	439	0	4.071194468	up	0	2.999568129	up	0	4.416650364	up	1.25E-29	3.857239198	up	--	--	Biological Process: signal transduction (GO:0007165);; 	"K17704|0|hsa:54518|APBB1IP, INAG1, PREL1, RARP1, RIAM; amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein; K17704 amyloid beta A4 precursor protein-binding family B member 1-interacting protein (A)"	Rap1 signaling pathway (ko04015);; Platelet activation (ko04611)	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain;; PH domain	Amyloid beta A4 precursor protein-binding family B member 1-interacting protein GN=APBB1IP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: amyloid beta A4 precursor protein-binding family B member 1-interacting protein [Orycteropus afer afer]
ENSG00000077454(LRCH4)	--	8.08845	428	7.099011503	356	6.976818396	374	7.135808384	365	6.661693274	347	6.4913779	340	0.921168563	-0.259536373	normal	0.966362511	-0.058118059	normal	0.958342676	-0.145179017	normal	0.585518535	-0.159955081	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Calponin homology (CH) domain;; Leucine rich repeat	Leucine-rich repeat and calponin homology domain-containing protein 4 GN=LRCH4 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: leucine-rich repeat and calponin homology domain-containing protein 4 [Tupaia chinensis]
ENSG00000077458(FAM76B)	--	3.721234002	182	5.463266	283	3.774604957	184	4.589369001	221	4.901599	253	5.191532137	214	0.935549478	0.247378235	normal	0.949522512	-0.182061608	normal	0.947039069	0.208026823	normal	0.906708571	0.062490177	normal	--	--	--	--	--	[S]	Function unknown	--	Protein FAM76B GN=FAM76B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM76B isoformX1 [Sus scrofa]
ENSG00000077463(SIRT6)	--	11.74049358	361	9.672541596	307	12.10687548	388	13.37963802	396	11.1970619	343	12.21299498	377	0.964317554	0.102253734	normal	0.958023535	0.137900471	normal	0.968346271	-0.049587488	normal	0.877704068	0.058635121	normal	[K]	Transcription	Molecular Function: NAD+ binding (GO:0070403);; 	K11416|0|ptr:737026|SIRT6; sirtuin 6; K11416 mono-ADP-ribosyltransferase sirtuin 6 [EC:2.4.2.31] (A)	Central carbon metabolism in cancer (ko05230)	[BK]	Chromatin structure and dynamics;; Transcription	Sir2 family	NAD-dependent protein deacetylase sirtuin-6 GN=SIRT6 OS=Homo sapiens (Human) PE=1 SV=2	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: NAD-dependent protein deacetylase sirtuin-6 [Ailuropoda melanoleuca]
ENSG00000077514(POLD3)	--	8.988814031	656	10.17059695	739	12.22638534	774	12.49839447	841	11.27993635	806	8.19479411	595	0.864046354	0.326900087	normal	0.97129998	0.103575922	normal	0.752944753	-0.386870631	normal	0.949764359	0.025789433	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; 	"K03504|0|hsa:10714|POLD3, P66, P68, PPP1R128; polymerase (DNA-directed), delta 3, accessory subunit; K03504 DNA polymerase delta subunit 3 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; HTLV-I infection (ko05166)	--	--	DNA polymerase subunit Cdc27	DNA polymerase delta subunit 3 GN=POLD3 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase delta subunit 3 isoform X1 [Equus caballus] 
ENSG00000077522(ACTN2)	--	0	0	0	0	0	0	0	0	0.010151886	0	0.01039828	1	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	"K05699|0|hsa:88|ACTN2, CMD1AA; actinin, alpha 2; K05699 actinin alpha (A)"	Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Amoebiasis (ko05146);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Ca2+ insensitive EF hand;; CAMSAP CH domain;; EF hand;; EF-hand domain pair;; EF-hand domain	Alpha-actinin-2 GN=ACTN2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: alpha-actinin-2 [Equus przewalskii]
ENSG00000077549(CAPZB)	--	111.2756318	3194	120.773444	3541	108.618642	3033	115.588798	3269	110.1607984	3146	106.474045	2992	0.99077046	0.00265154	normal	0.980880644	-0.191977684	normal	0.990102026	-0.027912752	normal	0.751757406	-0.075986756	normal	--	--	Cellular Component: F-actin capping protein complex (GO:0008290);; Biological Process: barbed-end actin filament capping (GO:0051016);; 	"K10365|0|pps:100978465|CAPZB; capping protein (actin filament) muscle Z-line, beta; K10365 capping protein (actin filament) muscle Z-line, beta (A)"	--	[Z]	Cytoskeleton	"F-actin capping protein, beta subunit"	F-actin-capping protein subunit beta GN=CAPZB OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: F-actin-capping protein subunit beta [Odobenus rosmarus divergens] 
ENSG00000077585(GPR137B)	--	13.64889105	339	15.433562	363	15.93648369	365	22.55452387	570	19.66120204	461	28.88606167	691	0.013084368	0.716314964	normal	0.872173605	0.322177162	normal	7.82E-05	0.909712819	normal	0.010616519	0.669893735	normal	--	--	--	--	--	--	--	--	Integral membrane protein GPR137B GN=GPR137B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: integral membrane protein GPR137B [Erinaceus europaeus]
ENSG00000077616(NAALAD2)	--	0.239954558	15	0.207047913	12	0.492522923	24	0.411332923	18	0.485696189	20	0.410825865	18	--	--	--	0.977837051	0.651414772	normal	0.983036267	-0.394533722	normal	--	--	--	--	--	--	K01301|0|pps:100970655|NAALAD2; N-acetylated alpha-linked acidic dipeptidase 2; K01301 N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21] (A)	--	[OPR]	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism;; General function prediction only"	Transferrin receptor-like dimerisation domain;; Peptidase family M28;; PA domain	N-acetylated-alpha-linked acidic dipeptidase 2 GN=NAALAD2 OS=Homo sapiens (Human) PE=1 SV=1	OP	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism"	PREDICTED: N-acetylated-alpha-linked acidic dipeptidase 2 [Ceratotherium simum simum]
ENSG00000077684(JADE1)	--	9.120497905	933	10.20788328	1082	9.389375818	939	14.33818128	1501	15.41558539	1569	15.39943766	1601	0.017999717	0.654285977	normal	0.299901611	0.514118426	normal	0.001124117	0.760535857	normal	8.43E-06	0.639922785	normal	--	--	--	"K11347|0|ptr:461484|JADE1, PHF17; jade family PHD finger 1; K11347 protein Jade-1 (A)"	--	[R]	General function prediction only	PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; Enhancer of polycomb-like;; PHD-finger;; PHD-finger	Protein Jade-1 GN=JADE1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein Jade-1 isoform X1 [Galeopterus variegatus]
ENSG00000077713(SLC25A43)	--	22.1572	1054	19.1562	911	21.2973	1010	14.9897	713	14.5289	688	13.0926	624	0.076002203	-0.593673542	normal	0.649154401	-0.425653029	normal	0.007662554	-0.701678935	normal	0.000238653	-0.576460984	normal	--	--	--	"K15120|0|hsa:203427|SLC25A43; solute carrier family 25, member 43; K15120 solute carrier family 25, member 43 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 43 GN=SLC25A43 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 43 [Bos taurus] 
ENSG00000077721(UBE2A)	--	66.74339964	1707	71.81436579	1812	66.50624818	1696	75.58535792	1996	68.131346	1747	70.7450844	1828	0.971158069	0.194654256	normal	0.983826571	-0.074066944	normal	0.982655043	0.099752766	normal	0.756831658	0.073685759	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10573|5.03095e-110|ocu:100339096|UBE2A; ubiquitin-conjugating enzyme E2A; K10573 ubiquitin-conjugating enzyme E2 A [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; Prokaryotic E2 family B	Ubiquitin-conjugating enzyme E2 A GN=UBE2A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 A [Oryctolagus cuniculus]
ENSG00000077782(FGFR1)	--	29.77046964	2789	25.04506641	2419	29.02176834	2761	30.8361042	2831	29.30022864	2766	21.9155686	2082	0.989728697	-0.009263384	normal	0.980163687	0.171863294	normal	0.730061108	-0.415249437	normal	0.794298891	-0.075363963	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04362|0|myb:102253832|FGFR1; fibroblast growth factor receptor 1; K04362 fibroblast growth factor receptor 1 [EC:2.7.10.1] (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Adherens junction (ko04520);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Prostate cancer (ko05215);; Melanoma (ko05218);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Fibroblast growth factor receptor 1 (Precursor) GN=FGFR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor receptor 1 isoform X1 [Myotis brandtii]
ENSG00000077800(FKBP6)	--	0	0	0	0	0	0	0.0370791	1	0.0364651	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09572|0|pps:100978678|FKBP6; FK506 binding protein 6, 36kDa; K09572 FK506-binding protein 6 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; TPR repeat	Inactive peptidyl-prolyl cis-trans isomerase FKBP6 GN=FKBP6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP6 isoform X1 [Bos mutus] 
ENSG00000077935(SMC1B)	--	0.0638589	6	0.02323582	2	0.011589479	0	0.03422009	3	0.029263958	2	0.022932736	2	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: chromosome (GO:0005694);; Biological Process: chromosome organization (GO:0051276);; 	K06636|0|pps:100979104|SMC1B; structural maintenance of chromosomes 1B; K06636 structural maintenance of chromosome 1 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114)	[D]	"Cell cycle control, cell division, chromosome partitioning"	RecF/RecN/SMC N terminal domain;; SMC proteins Flexible Hinge Domain;; AAA domain	Structural maintenance of chromosomes protein 1B GN=SMC1B OS=Homo sapiens (Human) PE=2 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: structural maintenance of chromosomes protein 1B isoform 1 [Ceratotherium simum simum]
ENSG00000077942(FBLN1)	--	48.40155939	1555	45.83517488	1595	49.61457663	1646	25.34399005	919	29.58935546	991	38.97396452	1275	0.000497123	-0.788583905	normal	0.00585463	-0.707166873	normal	0.799502254	-0.376364525	normal	2.10E-05	-0.610674061	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K17307|0|hsa:2192|FBLN1, FBLN, FIBL1; fibulin 1; K17307 fibulin 1/2 (A)"	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Coagulation Factor Xa inhibitory site;; EGF domain;; Anaphylotoxin-like domain;; EGF-like domain	Fibulin-1 (Precursor) GN=FBLN1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: fibulin-1 isoform 2 [Ceratotherium simum simum]
ENSG00000077984(CST7)	--	0.0732731	1	0	0	0	0	0	0	0.0709606	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	"K13903|2.98009e-105|hsa:8530|CST7, CMAP; cystatin F (leukocystatin); K13903 cystatin-F (A)"	--	--	--	Cystatin domain	Cystatin-F (Precursor) GN=CST7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cystatin-F [Galeopterus variegatus]
ENSG00000078018(MAP2)	--	1.170184904	89	0.937408635	83	0.388340914	37	0.342290867	46	0.996175994	108	0.467536708	65	0.160083983	-0.959536588	normal	0.92724329	0.352772813	normal	0.71341645	0.780267672	normal	0.97799303	0.046155994	normal	--	--	Molecular Function: tubulin binding (GO:0015631);; 	K10430|0|pps:100988836|MAP2; microtubule-associated protein 2; K10430 microtubule-associated protein 2 (A)	--	[Z]	Cytoskeleton	"MAP2/Tau projection domain;; Tau and MAP protein, tubulin-binding repeat"	Microtubule-associated protein 2 GN=MAP2 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: microtubule-associated protein 2 isoformX1 [Equus caballus]
ENSG00000078043(PIAS2)	--	4.81699626	436	5.452504434	514	4.83496044	426	4.898253457	418	5.363180598	416	5.6549653	421	0.966342738	-0.091328718	normal	0.866668705	-0.325544483	normal	0.970000389	-0.025234526	normal	0.577010037	-0.154186788	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K16063|0|hsa:9063|PIAS2, ARIP3, DIP, MIZ, MIZ1, PIASX, PIASX-ALPHA, PIASX-BETA, SIZ2, ZMIZ4; protein inhibitor of activated STAT, 2; K16063 E3 SUMO-protein ligase PIAS2 [EC:6.3.2.-] (A)"	Ubiquitin mediated proteolysis (ko04120);; Jak-STAT signaling pathway (ko04630);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[K]	Transcription	PINIT domain;; MIZ/SP-RING zinc finger	E3 SUMO-protein ligase PIAS2 GN=PIAS2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: E3 SUMO-protein ligase PIAS2 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000078053(AMPH)	--	0.22463452	14	0.112103033	7	0.189747586	11	0.096390937	6	0.046772865	2	0.079674002	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	"K12562|0|hsa:273|AMPH, AMPH1; amphiphysin; K12562 amphiphysin (A)"	Fc gamma R-mediated phagocytosis (ko04666)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	BAR domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Amphiphysin GN=AMPH OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: amphiphysin isoform 1 [Odobenus rosmarus divergens]
ENSG00000078061(ARAF)	--	25.03440392	1125	23.769143	1042	25.371921	1138	28.60946	1280	29.14714	1338	29.195974	1359	0.971388758	0.155187758	normal	0.864665009	0.338861289	normal	0.945202325	0.247452173	normal	0.167593618	0.246139091	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: receptor signaling protein activity (GO:0005057);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K08845|0|hsa:369|ARAF, A-RAF, ARAF1, PKS2, RAFA1; A-Raf proto-oncogene, serine/threonine kinase (EC:2.7.11.1); K08845 A-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] (A)"	ErbB signaling pathway (ko04012);; FoxO signaling pathway (ko04068);; Vascular smooth muscle contraction (ko04270);; Natural killer cell mediated cytotoxicity (ko04650);; Long-term potentiation (ko04720);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Alcoholism (ko05034);; Hepatitis C (ko05160);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Raf-like Ras-binding domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Kinase-like	Serine/threonine-protein kinase A-Raf GN=ARAF OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase A-Raf isoform 1 [Orcinus orca] 
ENSG00000078070(MCCC1)	--	5.713467402	288	6.393818128	329	5.600337994	282	6.979864	356	7.036482807	352	8.788548303	444	0.914811125	0.273661108	normal	0.96504773	0.075724743	normal	0.077223385	0.643798702	normal	0.167818422	0.337014036	normal	[I]	Lipid transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; Molecular Function: metal ion binding (GO:0046872);; 	K01968|0|pps:100976898|MCCC1; methylcrotonoyl-CoA carboxylase 1 (alpha); K01968 3-methylcrotonyl-CoA carboxylase alpha subunit [EC:6.4.1.4] (A)	"Valine, leucine and isoleucine degradation (ko00280)"	[IE]	Lipid transport and metabolism;; Amino acid transport and metabolism	"Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; Biotin-requiring enzyme;; ATP-grasp domain;; D-ala D-ala ligase C-terminus;; ATP-grasp domain;; RimK-like ATP-grasp domain;; Biotin-lipoyl like;; ATP-grasp domain"	"Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial (Precursor) GN=MCCC1 OS=Homo sapiens (Human) PE=1 SV=3"	EI	Amino acid transport and metabolism;; Lipid transport and metabolism	"PREDICTED: methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial [Orycteropus afer afer]"
ENSG00000078081(LAMP3)	--	0.221355777	10	0.131481056	4	0.185201356	9	0.207311964	8	0.357819603	13	0.235656806	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	"K06562|0|hsa:27074|LAMP3, CD208, DC_LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403; lysosomal-associated membrane protein 3; K06562 lysosomal-associated membrane protein 3 (A)"	Lysosome (ko04142)	[R]	General function prediction only	Lysosome-associated membrane glycoprotein (Lamp)	Lysosome-associated membrane glycoprotein 3 (Precursor) GN=LAMP3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: lysosome-associated membrane glycoprotein 3 [Myotis brandtii]
ENSG00000078098(FAP)	--	0.11728423	5	0	0	0.023444723	0	0.02331842	1	0.02258263	0	0.046675092	2	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: triglyceride lipase activity (GO:0004806);; Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Biological Process: lipid catabolic process (GO:0016042);; 	"K08674|0|ptr:459691|FAP; fibroblast activation protein, alpha; K08674 fibroblast activation protein, alpha [EC:3.4.21.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Dipeptidyl peptidase IV (DPP IV) N-terminal region;; Prolyl oligopeptidase family;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; Secretory lipase	"Antiplasmin-cleaving enzyme FAP, soluble form {ECO:0000303|PubMed:14751930} OS=Homo sapiens (Human) PE=1 SV=5"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: seprase [Oryctolagus cuniculus]
ENSG00000078114(NEBL)	--	17.47835113	1256	18.26692666	1323	25.60681691	1189	6.130047519	382	7.328656	461	4.823136521	357	0	-1.743916215	down	5.55E-16	-1.539276921	down	0	-1.739756725	down	8.17E-31	-1.672180637	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Nebulin repeat;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Nebulette GN=NEBL OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: LIM zinc-binding domain-containing Nebulette isoform 1 [Trichechus manatus latirostris]
ENSG00000078124(ACER3)	--	21.15719591	1742	22.32911478	1805	22.28437219	1728	15.93047554	1455	14.88952908	1443	16.14803545	1435	0.925897886	-0.290277132	normal	0.871475879	-0.344030965	normal	0.935788558	-0.276078383	normal	0.061952115	-0.305086255	normal	--	--	"Biological Process: ceramide metabolic process (GO:0006672);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811);; "	"K04711|0|ptr:748831|ACER3, PHCA; alkaline ceramidase 3; K04711 dihydroceramidase [EC:3.5.1.-] (A)"	Sphingolipid metabolism (ko00600)	[I]	Lipid transport and metabolism	Ceramidase	Alkaline ceramidase 3 GN=ACER3 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: alkaline ceramidase 3 isoform X1 [Camelus bactrianus] 
ENSG00000078140(UBE2K)	--	30.67328288	1724	29.85195762	1846	31.28434331	1670	33.76334394	1976	32.5740236	1896	29.73064276	1658	0.976364203	0.165852775	normal	0.98581968	0.017116018	normal	0.985032221	-0.018678562	normal	0.824615068	0.05588974	normal	--	--	--	K04649|1.2187e-136|ssc:780416|UBC1; K04649 ubiquitin-conjugating enzyme (huntingtin interacting protein 2) [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; UBA/TS-N domain;; Prokaryotic E2 family B	Ubiquitin-conjugating enzyme E2 K GN=UBE2K OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	ubiquitin-conjugating enzyme E2 K [Bos taurus] 
ENSG00000078142(PIK3C3)	--	6.326345124	505	7.060420088	551	8.040366313	595	6.7185084	535	5.428319736	443	6.372871941	556	0.970907033	0.052268734	normal	0.854322321	-0.335144036	normal	0.968057183	-0.10581794	normal	0.636256921	-0.12700014	normal	--	--	Molecular Function: kinase activity (GO:0016301);; 	"K00914|0|ptr:455385|PIK3C3; phosphatidylinositol 3-kinase, catalytic subunit type 3; K00914 phosphatidylinositol 3-kinase [EC:2.7.1.137] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Regulation of autophagy (ko04140);; Phagosome (ko04145);; Tuberculosis (ko05152)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Phosphoinositide 3-kinase family, accessory domain (PIK domain);; Phosphatidylinositol 3- and 4-kinase;; Phosphoinositide 3-kinase C2"	Phosphatidylinositol 3-kinase catalytic subunit type 3 GN=PIK3C3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 3-kinase catalytic subunit type 3 [Pantholops hodgsonii]
ENSG00000078177(N4BP2)	--	2.999787346	517	3.481415655	574	3.137515399	521	2.651693084	459	2.996538058	513	3.109305723	511	0.946997606	-0.201865205	normal	0.953154071	-0.183008117	normal	0.971586068	-0.036145581	normal	0.591848458	-0.141272008	normal	--	--	--	"K15720|0|hsa:55728|N4BP2, B3BP; NEDD4 binding protein 2; K15720 NEDD4-binding protein 2 [EC:3.-.-.-] (A)"	--	[L]	"Replication, recombination and repair"	Domain of unknown function (DUF1771);; Smr domain;; AAA domain;; CUE domain	NEDD4-binding protein 2 GN=N4BP2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: NEDD4-binding protein 2 [Ceratotherium simum simum]
ENSG00000078237(TIGAR)	--	13.0960505	786	16.02045064	1011	14.02351053	879	15.58413082	991	15.88524054	1024	16.81803075	1050	0.895699537	0.302995051	normal	0.979287247	-0.002989397	normal	0.938892934	0.247772307	normal	0.395370111	0.174710474	normal	[G]	Carbohydrate transport and metabolism	--	"K14634|0|hsa:57103|C12orf5, FR2BP, TIGAR; chromosome 12 open reading frame 5 (EC:3.1.3.46); K14634 fructose-2,6-bisphosphatase [EC:3.1.3.46] (A)"	Fructose and mannose metabolism (ko00051);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Histidine phosphatase superfamily (branch 1)	"Fructose-2,6-bisphosphatase TIGAR GN=TIGAR OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: fructose-2,6-bisphosphatase TIGAR [Loxodonta africana]"
ENSG00000078246(TULP3)	--	10.40483092	579	10.43603992	558	10.07211879	594	12.43903434	688	10.17363663	570	10.8193393	620	0.944531053	0.21748304	normal	0.972312077	0.009245448	normal	0.972645983	0.053380811	normal	0.726852116	0.096094752	normal	--	--	--	--	--	[R]	General function prediction only	Tub family	Tubby-related protein 3 GN=TULP3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: tubby-related protein 3 [Orycteropus afer afer]
ENSG00000078269(SYNJ2)	--	22.42228673	2400	24.51643159	2872	24.87154352	2625	21.58443031	2031	18.57054169	1792	20.67838345	1945	0.948735654	-0.271487225	normal	0.006067542	-0.701439475	normal	0.630849459	-0.440542716	normal	0.001194988	-0.474650628	normal	[T]	Signal transduction mechanisms	Molecular Function: phosphoric ester hydrolase activity (GO:0042578);; 	K01099|0|ggo:101131117|SYNJ2; synaptojanin-2; K01099 phosphatidylinositol-bisphosphatase [EC:3.1.3.36] (A)	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SacI homology domain;; Domain of unknown function (DUF1866);; Endonuclease/Exonuclease/phosphatase family	Synaptojanin-2 GN=SYNJ2 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: synaptojanin-2 [Trichechus manatus latirostris]
ENSG00000078304(PPP2R5C)	--	55.94385984	1880	56.20347651	1893	55.68198017	1973	56.167165	1969	57.82680077	1958	56.98232953	1890	0.986172299	0.035869542	normal	0.98597669	0.027258385	normal	0.985208937	-0.07024115	normal	0.993962806	-0.003505038	normal	--	--	Cellular Component: protein phosphatase type 2A complex (GO:0000159);; Biological Process: signal transduction (GO:0007165);; Molecular Function: protein phosphatase regulator activity (GO:0019888);; 	"K11584|0|hsa:5527|PPP2R5C, B56G, PR61G; protein phosphatase 2, regulatory subunit B', gamma; K11584 serine/threonine-protein phosphatase 2A regulatory subunit B' (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Dopaminergic synapse (ko04728)	[T]	Signal transduction mechanisms	Protein phosphatase 2A regulatory B subunit (B56 family)	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform GN=PPP2R5C OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform isoform X3 [Equus caballus]
ENSG00000078369(GNB1)	--	124.0853717	6497	120.8415801	6515	120.9233852	6384	125.3407665	6809	115.2050666	6321	108.8182029	6040	0.994636163	0.036828457	normal	0.993924017	-0.065023597	normal	0.993480327	-0.088182065	normal	0.895327936	-0.03850357	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K04536|0|umr:103682042|GNB1; guanine nucleotide binding protein (G protein), beta polypeptide 1; K04536 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Taste transduction (ko04742);; Phototransduction (ko04744);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[R]	General function prediction only	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 GN=GNB1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 isoform X1 [Physeter catodon] 
ENSG00000078399(HOXA9)	--	3.400317922	111	3.387793065	101	2.874382432	95	5.489528152	165	5.696141	176	5.160389615	159	0.678257084	0.534965934	normal	0.115628291	0.770944789	normal	0.22898787	0.725711778	normal	0.033701583	0.682264828	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K09294|3.66454e-169|hsa:3205|HOXA9, ABD-B, HOX1, HOX1.7, HOX1G; homeobox A9; K09294 homeobox protein HoxA/B/C/D9 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Hox9 activation region;; Homeobox domain	Homeobox protein Hox-A9 GN=HOXA9 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: homeobox protein Hox-A9 [Sus scrofa] 
ENSG00000078401(EDN1)	--	30.51044	1110	40.18107	1447	38.00651	1332	29.44448	1027	33.57314	1171	32.73088	1165	0.971532923	-0.14275026	normal	0.88514326	-0.326370436	normal	0.962282021	-0.20131098	normal	0.233061138	-0.230406341	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: regulation of vasoconstriction (GO:0019229);; 	"K16366|4.35077e-132|hsa:1906|EDN1, ARCND3, ET1, HDLCQ7, PPET1, QME; endothelin 1; K16366 endothelin-1 (A)"	HIF-1 signaling pathway (ko04066);; TNF signaling pathway (ko04668);; Melanogenesis (ko04916)	--	--	Endothelin family	Big endothelin-1 (Precursor) GN=EDN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	endothelin-1 precursor [Equus caballus]
ENSG00000078403(MLLT10)	--	13.01815249	953	12.706167	989	13.77335583	1100	12.99196815	979	11.72055918	909	12.47835771	1016	0.979122306	0.007987677	normal	0.969372252	-0.142888793	normal	0.974081818	-0.122718961	normal	0.721029296	-0.087871743	normal	--	--	--	--	--	[R]	General function prediction only	PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; PHD-finger;; PHD-finger	Protein AF-10 GN=MLLT10 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein AF-10 [Oryctolagus cuniculus]
ENSG00000078487(ZCWPW1)	--	0.9186257	43	0.524800459	28	0.512930764	25	0.589227777	32	0.656213942	27	0.767549029	33	0.964000599	-0.438850513	normal	0.984679066	-0.070041331	normal	0.977167075	0.372575635	normal	0.949356766	-0.083063487	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	PWWP domain;; CW-type Zinc Finger	Zinc finger CW-type PWWP domain protein 1 GN=ZCWPW1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger CW-type PWWP domain protein 1 isoform X1 [Equus przewalskii]
ENSG00000078549(ADCYAP1R1)	--	0.016469193	2	0	0	0.016085205	1	0.008253594	1	0.008060337	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04587|0|rno:24167|Adcyap1r1, PAC1-R, PACAP-R1, PACAP-R1A, PACAPR1, PACAPR1A; adenylate cyclase activating polypeptide 1 receptor 1; K04587 pituitary adenylate cyclase-activating polypeptide type I receptor (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Insulin secretion (ko04911)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Pituitary adenylate cyclase-activating polypeptide type I receptor (Precursor) GN=ADCYAP1R1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	hypothetical protein PANDA_007929 [Ailuropoda melanoleuca]
ENSG00000078579(FGF20)	--	0.118593847	3	0.436883858	10	0.302935481	6	0.043366013	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|3.63208e-122|ptr:739665|FGF20; fibroblast growth factor 20; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 20 GN=FGF20 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	fibroblast growth factor 20 [Sus scrofa] 
ENSG00000078596(ITM2A)	--	0.412999625	9	0.044700113	1	0.0455302	0	0.136949274	3	0.222955192	4	0.09145845	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K18241|0|ptr:742537|ITM2A; integral membrane protein 2A; K18241 integral membrane protein 2A (A)	--	[S]	Function unknown	BRICHOS domain	Integral membrane protein 2A GN=ITM2A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: integral membrane protein 2A [Oryctolagus cuniculus]
ENSG00000078618(NRDC)	--	50.88264624	3822	51.2719906	3907	52.01540767	3899	46.610951	3507	45.06741901	3360	47.0679258	3552	0.986330448	-0.154857594	normal	0.973255064	-0.238926743	normal	0.987427809	-0.142706	normal	0.348469045	-0.179544102	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K01411|0|mcf:102123458|NRD1; nardilysin (N-arginine dibasic convertase); K01411 nardilysin [EC:3.4.24.61] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Insulinase (Peptidase family M16);; Peptidase M16 inactive domain	Nardilysin (Precursor) GN=NRD1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nardilysin isoform X1 [Oryctolagus cuniculus]
ENSG00000078668(VDAC3)	--	104.0144646	2253	116.4426412	2535	115.7832331	2515	114.5011	2529	100.7463408	2117	104.0109192	2289	0.983324171	0.13580002	normal	0.945908393	-0.281207176	normal	0.982621518	-0.144041553	normal	0.669140257	-0.096093421	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: transmembrane transport (GO:0055085);; 	"K15041|0|hsa:7419|VDAC3, HD-VDAC3, VDAC-3; voltage-dependent anion channel 3; K15041 voltage-dependent anion channel protein 3 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Parkinson's disease (ko05012);; Huntington's disease (ko05016);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[P]	Inorganic ion transport and metabolism	Eukaryotic porin	Voltage-dependent anion-selective channel protein 3 GN=VDAC3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent anion-selective channel protein 3 isoform X3 [Equus caballus]
ENSG00000078674(PCM1)	--	23.35770129	3185	26.99230616	3755	22.92547631	3354	28.4084294	3965	28.31384829	3941	37.3565256	5142	0.956017172	0.285071781	normal	0.991270734	0.048303294	normal	0.061239818	0.607932456	normal	0.164595847	0.321501656	normal	--	--	--	"K16537|0|hsa:5108|PCM1, PTC4; pericentriolar material 1; K16537 pericentriolar material 1 protein (A)"	--	--	--	--	Pericentriolar material 1 protein GN=PCM1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: pericentriolar material 1 protein isoformX2 [Equus caballus]
ENSG00000078687(TNRC6C)	--	0.863088793	166	1.173967859	155	0.584931315	113	1.17254984	235	1.064527295	227	2.014355961	261	0.710756648	0.466996686	normal	0.584851248	0.524743668	normal	1.15E-05	1.188669724	up	0.006938149	0.714830751	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K18412|0|ptr:741899|TNRC6C; trinucleotide repeat containing 6C; K18412 trinucleotide repeat-containing gene 6 protein (A)	--	--	--	"M domain of GW182;; Argonaute hook;; UBA/TS-N domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Trinucleotide repeat-containing gene 6C protein GN=TNRC6C OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: trinucleotide repeat-containing gene 6C protein-like [Myotis lucifugus]
ENSG00000078699(CBFA2T2)	--	4.92352444	567	4.996000621	664	5.752771494	703	4.458327031	563	4.25264941	575	5.441051113	680	0.972270837	-0.040934759	normal	0.939684625	-0.228488057	normal	0.97401289	-0.056158544	normal	0.676356303	-0.109657194	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	NHR2 domain like;; NHR1 homology to TAF;; MYND finger	Protein CBFA2T2 GN=CBFA2T2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein CBFA2T2 isoform X1 [Camelus ferus] 
ENSG00000078725(BRINP1)	--	0.09075254	6	0.1517249	7	0.058185321	3	0.1527937	10	0.1501057	6	0.059104079	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MAC/Perforin domain	BMP/retinoic acid-inducible neural-specific protein 1 (Precursor) GN=BRINP1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: BMP/retinoic acid-inducible neural-specific protein 1 [Loxodonta africana] 
ENSG00000078747(ITCH)	--	14.909215	1556	14.37473311	1538	17.16427598	1679	16.51728962	1657	16.8358565	1719	14.78014941	1548	0.983661588	0.059842016	normal	0.977819651	0.138958195	normal	0.979498566	-0.125370561	normal	0.938411638	0.023733118	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	"K05632|0|hsa:83737|ITCH, ADMFD, AIF4, AIP4, NAPP1, dJ468O1.1; itchy E3 ubiquitin protein ligase; K05632 atrophin-1 interacting protein 4 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; TNF signaling pathway (ko04668);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain;; C2 domain	E3 ubiquitin-protein ligase Itchy homolog GN=ITCH OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase Itchy homolog isoform X1 [Camelus ferus]
ENSG00000078795(PKD2L2)	--	0	0	0	0	0.0414545	0	0.0407435	1	0.0798206	1	0.1328584	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04991|0|ptr:745945|PKD2L2; polycystic kidney disease 2-like 2; K04991 polycystin 2L2 (A)	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Polycystin cation channel;; Ion transport protein	Polycystic kidney disease 2-like 2 protein GN=PKD2L2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: polycystic kidney disease 2-like 2 protein isoform X2 [Canis lupus familiaris] 
ENSG00000078804(TP53INP2)	--	5.771087	386	5.232981392	361	5.526402136	374	5.729534291	391	7.634230842	514	7.732108	533	0.969394388	-0.012216191	normal	0.484700749	0.486626477	normal	0.411075858	0.501099979	normal	0.127737876	0.339068123	normal	--	--	--	--	--	--	--	DOR family	Tumor protein p53-inducible nuclear protein 2 GN=TP53INP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: tumor protein p53-inducible nuclear protein 2-like [Lipotes vexillifer]
ENSG00000078808(SDF4)	--	70.507544	2719	69.187013	2714	67.085498	2670	70.29090653	2735	70.96762	2728	75.57584	2935	0.98940958	-0.022354987	normal	0.989151834	-0.013995856	normal	0.985692365	0.128160062	normal	0.911866656	0.030573924	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[R]	General function prediction only	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	45 kDa calcium-binding protein (Precursor) GN=SDF4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: 45 kDa calcium-binding protein [Galeopterus variegatus]
ENSG00000078814(MYH7B)	--	0.053462592	8	0.045286019	7	0.050690098	7	0.127571152	6	0.093863881	3	0.020120241	3	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10352|0|hsa:57644|MYH7B, MHC14, MYH14; myosin, heavy chain 7B, cardiac muscle, beta; K10352 myosin heavy chain (A)"	Tight junction (ko04530)	[Z]	Cytoskeleton	Myosin tail;; Myosin head (motor domain);; Myosin N-terminal SH3-like domain	Myosin-7B GN=MYH7B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: myosin-7B [Ceratotherium simum simum]
ENSG00000078900(TP73)	--	0.404268773	33	0.330211	35	0.347101675	34	0.030669849	3	0.066723528	5	0.150732	15	0.000311244	-2.953410432	down	0.001498319	-2.505642385	down	0.748112233	-1.112513496	normal	0.000256484	-2.165544482	down	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: transcription regulatory region DNA binding (GO:0044212);; Biological Process: protein tetramerization (GO:0051262);; 	K10148|0|ggo:101138252|TP73; tumor protein p73 isoform 1; K10148 tumor protein p73 (A)	p53 signaling pathway (ko04115);; Hippo signaling pathway (ko04390);; Neurotrophin signaling pathway (ko04722);; Measles (ko05162)	--	--	P53 DNA-binding domain;; P53 tetramerisation motif;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Tumor protein p73 GN=TP73 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: tumor protein p73 [Tupaia chinensis]
ENSG00000078902(TOLLIP)	--	20.068988	1061	20.9842016	1245	20.3937582	1133	21.75224659	1207	19.72036016	1163	25.76553197	1426	0.970509994	0.154958275	normal	0.975764521	-0.11957089	normal	0.885207229	0.323149405	normal	0.579869857	0.121709785	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05402|5.09696e-165|pon:100442943|TOLLIP; toll interacting protein; K05402 toll-interacting protein (A)	Toll-like receptor signaling pathway (ko04620)	--	--	CUE domain;; C2 domain	Toll-interacting protein GN=TOLLIP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: toll-interacting protein isoformX1 [Canis lupus familiaris]
ENSG00000078967(UBE2D4)	--	4.14194	232	4.86896	230	4.301293	272	4.1599	263	4.338757	259	4.627267	275	0.956951639	0.149177455	normal	0.955858398	0.148968266	normal	0.967456495	0.007492098	normal	0.80267802	0.098036011	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K06689|1.23325e-106|ssc:100524597|UBE2D4; ubiquitin-conjugating enzyme E2D 4 (putative); K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 D4 GN=UBE2D4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 D4 isoform 1 [Ovis aries] 
ENSG00000079101(CLUL1)	--	0.087590902	3	0.127469369	5	0.18409126	6	0.059968293	3	0.0686476	2	0.087036233	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Clusterin;; Putative binding domain	Clusterin-like protein 1 (Precursor) GN=CLUL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: clusterin-like protein 1 [Lipotes vexillifer]
ENSG00000079112(CDH17)	--	0.14366271	10	0.241284313	14	0.159348753	10	2.033328217	143	2.842790385	198	2.703658353	190	0	3.618544851	up	0	3.66469346	up	0	4.048476388	up	7.54E-27	3.94443045	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06811|0|hsa:1015|CDH17, CDH16, HPT-1, HPT1; cadherin 17, LI cadherin (liver-intestine); K06811 cadherin 17, LI cadherin (A)"	--	[S]	Function unknown	Cadherin domain	Cadherin-17 (Precursor) GN=CDH17 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: cadherin-17 [Equus caballus] 
ENSG00000079134(THOC1)	--	9.117859781	360	9.787565544	367	9.522560035	387	9.048769956	380	10.3371144	411	8.690024387	329	0.968104043	0.046975109	normal	0.958555482	0.141381049	normal	0.930797797	-0.241512655	normal	0.980122653	-0.013667891	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K12878|0|hsa:9984|THOC1, HPR1, P84, P84N5; THO complex 1; K12878 THO complex subunit 1 (A)"	RNA transport (ko03013);; Spliceosome (ko03040)	[Y]	Nuclear structure	THO complex subunit 1 transcription elongation factor;; Death domain	THO complex subunit 1 GN=THOC1 OS=Homo sapiens (Human) PE=1 SV=1	Y	Nuclear structure	PREDICTED: THO complex subunit 1 [Ursus maritimus]
ENSG00000079150(FKBP7)	--	3.362349809	141	3.213212785	132	3.59748036	120	4.565393	175	5.673148	212	3.882330674	147	0.931644244	0.278103216	normal	0.254069713	0.656117236	normal	0.936511815	0.281282459	normal	0.215636647	0.420576802	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K09573|7.01942e-164|pps:100979584|FKBP7; FK506 binding protein 7; K09573 FK506-binding protein 7 [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; EF-hand domain pair;; EF hand;; EF hand;; EF-hand domain	Peptidyl-prolyl cis-trans isomerase FKBP7 (Precursor) GN=FKBP7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP7 [Ceratotherium simum simum]
ENSG00000079156(OSBPL6)	--	2.707529583	230	2.7208336	204	2.201830754	187	1.338934256	114	1.437167512	117	1.229492742	103	0.000540256	-1.033416042	down	0.039118433	-0.815399017	normal	0.027719408	-0.859184184	normal	0.000984353	-0.916426637	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Oxysterol-binding protein;; Pleckstrin homology domain	Oxysterol-binding protein-related protein 6 GN=OSBPL6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 6 isoform X2 [Tupaia chinensis]
ENSG00000079215(SLC1A3)	--	0.228631325	15	0.903689245	24	0.78783103	42	0.273748424	14	0.318566711	23	0.560087529	40	--	--	--	0.986337265	-0.077817716	normal	0.980771935	-0.075880758	normal	0.962333677	-0.089811456	normal	[C]	Energy production and conversion	Molecular Function: symporter activity (GO:0015293);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05614|0|ptr:461918|SLC1A3; solute carrier family 1 (glial high affinity glutamate transporter), member 3; K05614 solute carrier family 1 (glial high affinity glutamate transporter), member 3 (A)"	Glutamatergic synapse (ko04724)	[E]	Amino acid transport and metabolism	Sodium:dicarboxylate symporter family	Excitatory amino acid transporter 1 GN=SLC1A3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: excitatory amino acid transporter 1 isoform 1 [Equus caballus] 
ENSG00000079246(XRCC5)	--	123.363249	7665	122.897353	7634	129.795711	7981	95.68435444	5962	98.5934044	6041	75.2621945	4678	0.882244974	-0.393232032	normal	0.931203017	-0.358998208	normal	0.000604215	-0.77877401	normal	0.001184021	-0.50263375	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Biological Process: double-strand break repair via nonhomologous end joining (GO:0006303);; Molecular Function: hydrolase activity, acting on acid anhydrides (GO:0016817);; "	"K10885|0|hsa:7520|XRCC5, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV; X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining); K10885 ATP-dependent DNA helicase 2 subunit 2 (A)"	Non-homologous end-joining (ko03450)	[L]	"Replication, recombination and repair"	Ku70/Ku80 N-terminal alpha/beta domain;; Ku C terminal domain like;; Ku70/Ku80 beta-barrel domain;; Ku70/Ku80 C-terminal arm	X-ray repair cross-complementing protein 5 GN=XRCC5 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: X-ray repair cross-complementing protein 5 [Ceratotherium simum simum]
ENSG00000079257(LXN)	--	14.2552	277	10.4667	203	12.39	241	11.8153	234	16.6589	324	12.6134	248	0.919610736	-0.272562436	normal	0.131002669	0.649226905	normal	0.966717578	0.032812555	normal	0.715293745	0.139981027	normal	--	--	--	--	--	--	--	Latexin	Latexin GN=LXN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: latexin [Ailuropoda melanoleuca] 
ENSG00000079263(SP140)	--	0	0	0	0	0	0	0.1522035	6	0.037634611	2	0.168374	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Sp100 domain;; SAND domain;; Bromodomain;; PHD-finger	Nuclear body protein SP140 {ECO:0000312|HGNC:HGNC:17133} OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nuclear body protein SP140 [Odobenus rosmarus divergens]
ENSG00000079277(MKNK1)	--	11.920615	628	12.246239	544	11.4489852	558	12.334442	613	14.968513	702	11.550049	582	0.972139558	-0.065547424	normal	0.83896089	0.345590098	normal	0.971999307	0.052323729	normal	0.675455817	0.111639204	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04372|0|mcf:102129375|MKNK1; MAP kinase interacting serine/threonine kinase 1; K04372 MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010);; HIF-1 signaling pathway (ko04066);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	MAP kinase-interacting serine/threonine-protein kinase 1 GN=MKNK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: MAP kinase-interacting serine/threonine-protein kinase 1 isoform X1 [Mustela putorius furo] 
ENSG00000079308(TNS1)	--	0.544291774	104	0.301141615	56	0.540949519	80	2.88986382	337	1.962120477	438	1.142063173	166	6.88E-12	1.651031683	up	0	2.912853348	up	0.003920803	1.031000358	up	0.010692121	1.948731192	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K18080|0|hsa:7145|TNS1, MST091, MST122, MST127, MSTP122, MSTP127, MXRA6, PPP1R155, TNS; tensin 1; K18080 tensin (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	Phosphotyrosine-binding domain;; C2 domain of PTEN tumour-suppressor protein;; SH2 domain	Tensin-1 GN=TNS1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tensin-1-like [Tupaia chinensis]
ENSG00000079313(REXO1)	--	6.18891	613	6.44913	644	6.83594	702	6.817483249	673	6.92198	688	7.219382	724	0.96946446	0.103639207	normal	0.971874254	0.073753741	normal	0.975157732	0.036150538	normal	0.813067828	0.069153583	normal	[L]	"Replication, recombination and repair"	--	"K14570|0|hsa:57455|REXO1, ELOABP1, EloA-BP1, REX1, TCEB3BP1; REX1, RNA exonuclease 1 homolog (S. cerevisiae); K14570 RNA exonuclease 1 [EC:3.1.-.-] (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[L]	"Replication, recombination and repair"	Exonuclease	RNA exonuclease 1 homolog GN=REXO1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: RNA exonuclease 1 homolog isoform X2 [Bubalus bubalis]
ENSG00000079332(SAR1A)	--	33.75053506	1467	34.65263707	1541	34.13138068	1479	40.67058867	1810	43.33329522	1902	37.0892286	1625	0.939190912	0.272031695	normal	0.935704654	0.281974357	normal	0.978782039	0.127401904	normal	0.194143357	0.228786806	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07953|5.40549e-145|ptr:100608758|SAR1A; secretion associated, Ras related GTPase 1A; K07953 GTP-binding protein SAR1 [EC:3.6.5.-] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Legionellosis (ko05134)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Ras family;; Miro-like protein;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	GTP-binding protein SAR1a GN=SAR1A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: GTP-binding protein SAR1a [Ceratotherium simum simum]
ENSG00000079335(CDC14A)	--	2.301853593	136	2.142225419	108	2.083602418	131	1.481833078	96	1.622116358	95	1.43973115	87	0.751986558	-0.526217736	normal	0.958198354	-0.203418963	normal	0.654357666	-0.590349783	normal	0.255385295	-0.453092393	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K06639|0|pon:100455582|CDC14A; cell division cycle 14A; K06639 cell division cycle 14 [EC:3.1.3.16 3.1.3.48] (A)	Cell cycle (ko04110)	[V]	Defense mechanisms	"Dual specificity protein phosphatase, N-terminal half;; Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase CDC14A GN=CDC14A OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase CDC14A [Felis catus]
ENSG00000079337(RAPGEF3)	--	0.313378676	26	0.229456	22	0.261212978	24	0.4190914	23	0.394960436	33	0.385441286	34	0.985843369	-0.195422705	normal	0.965386526	0.533427165	normal	0.970744645	0.469256873	normal	0.729684355	0.301973028	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K08014|0|hsa:10411|RAPGEF3, CAMP-GEFI, EPAC, EPAC1, HSU79275, bcm910; Rap guanine nucleotide exchange factor (GEF) 3; K08014 Rap guanine nucleotide exchange factor 3 (A)"	Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Leukocyte transendothelial migration (ko04670);; Long-term potentiation (ko04720);; Serotonergic synapse (ko04726)	[T]	Signal transduction mechanisms	"RasGEF domain;; Cyclic nucleotide-binding domain;; RasGEF N-terminal motif;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	Rap guanine nucleotide exchange factor 3 GN=RAPGEF3 OS=Homo sapiens (Human) PE=1 SV=6	T	Signal transduction mechanisms	PREDICTED: rap guanine nucleotide exchange factor 3 isoformX1 [Equus caballus] 
ENSG00000079385(CEACAM1)	--	0.175651904	7	0.20580207	11	0.26857288	9	1.3557433	89	2.50339479	155	2.291093521	150	5.40E-13	3.378992671	up	0	3.624830535	up	0	3.841632575	up	1.87E-11	3.847439354	up	--	--	--	K06499|0|ggo:101147352|CEACAM1; carcinoembryonic antigen-related cell adhesion molecule 1 isoform 1; K06499 carcinoembryonic antigen-related cell adhesion molecule (A)	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E;; Natural killer cell receptor 2B4	Carcinoembryonic antigen-related cell adhesion molecule 1 (Precursor) GN=CEACAM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1-like [Ceratotherium simum simum]
ENSG00000079387(SENP1)	--	8.821120301	667	7.968587	607	8.907172006	647	8.86192	676	9.257775158	743	8.414729	608	0.974863572	-0.011469535	normal	0.918991659	0.269631091	normal	0.969894481	-0.097750093	normal	0.853435447	0.056118482	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K08592|0|hsa:29843|SENP1, SuPr-2; SUMO1/sentrin specific peptidase 1 (EC:3.4.22.68); K08592 sentrin-specific protease 1 [EC:3.4.22.68] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ulp1 protease family, C-terminal catalytic domain"	Sentrin-specific protease 1 GN=SENP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sentrin-specific protease 1 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000079393(DUSP13)	--	0	0	0	0	0.16728522	1	0.119795	1	0	0	0.125799	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14165|0|pps:100989913|DUSP13; dual specificity phosphatase 13; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 13 isoform B GN=DUSP13 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 13 isoform B isoform X2 [Panthera tigris altaica]
ENSG00000079432(CIC)	--	34.09163693	4431	38.49443724	5294	37.38129314	4993	29.58351679	4267	33.55447222	4286	35.07453909	4965	0.991487414	-0.085212367	normal	0.942873345	-0.326049171	normal	0.993351224	-0.01639965	normal	0.491191189	-0.143437006	normal	--	--	--	--	--	[K]	Transcription	HMG (high mobility group) box;; HMG-box domain	Protein capicua homolog GN=CIC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	Protein capicua like protein [Pteropus alecto]
ENSG00000079435(LIPE)	--	2.35860039	98	2.8252312	84	2.953438106	72	1.779813788	70	1.6970686	64	1.3680524	54	0.857384286	-0.506809461	normal	0.926578966	-0.405356005	normal	0.938657698	-0.413271484	normal	0.35115444	-0.45641171	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Biological Process: cholesterol metabolic process (GO:0008203);; Biological Process: lipid catabolic process (GO:0016042);; Molecular Function: lipase activity (GO:0016298);; Molecular Function: hydrolase activity (GO:0016787);; 	"K07188|0|hsa:3991|LIPE, AOMS4, HSL, LHS; lipase, hormone-sensitive (EC:3.1.1.79); K07188 hormone-sensitive lipase [EC:3.1.1.79] (A)"	cAMP signaling pathway (ko04024);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910)	[I]	Lipid transport and metabolism	Hormone-sensitive lipase (HSL) N-terminus;; alpha/beta hydrolase fold;; Protein of unknown function (DUF2424)	Hormone-sensitive lipase GN=LIPE OS=Homo sapiens (Human) PE=1 SV=4	I	Lipid transport and metabolism	PREDICTED: hormone-sensitive lipase [Galeopterus variegatus]
ENSG00000079459(FDFT1)	--	132.7491174	4683	113.516149	4329	148.0843061	5183	48.3175516	1831	56.54333126	2097	93.74967225	3350	3.77E-15	-1.384878669	down	2.62E-08	-1.066585886	down	0.029603599	-0.637684418	normal	7.64E-05	-0.98287089	normal	[I]	Lipid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: transferase activity (GO:0016740);; 	K00801|0|mcf:102131949|FDFT1; farnesyl-diphosphate farnesyltransferase 1; K00801 farnesyl-diphosphate farnesyltransferase [EC:2.5.1.21] (A)	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	Squalene/phytoene synthase	Squalene synthase GN=FDFT1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: squalene synthase isoform X1 [Oryctolagus cuniculus]
ENSG00000079462(PAFAH1B3)	--	77.81428861	1305	73.11227493	1307	75.63589463	1375	51.68901641	837	54.09481252	921	63.18448858	1013	0.01271113	-0.670587842	normal	0.255166491	-0.525684052	normal	0.552081546	-0.448511857	normal	0.000250403	-0.545408919	normal	--	--	--	"K16795|1.24743e-157|ptr:456074|PAFAH1B3; platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa); K16795 platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47] (A)"	Ether lipid metabolism (ko00565)	[TV]	Signal transduction mechanisms;; Defense mechanisms	GDSL-like Lipase/Acylhydrolase family;; GDSL-like Lipase/Acylhydrolase	Platelet-activating factor acetylhydrolase IB subunit gamma GN=PAFAH1B3 OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: platelet-activating factor acetylhydrolase IB subunit gamma [Trichechus manatus latirostris]
ENSG00000079482(OPHN1)	--	2.727172993	383	3.046627104	447	2.970201275	421	3.11721831	439	2.746850097	396	3.604920497	506	0.955209843	0.165424119	normal	0.947202567	-0.195497732	normal	0.923497	0.256185203	normal	0.810971789	0.079409178	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain	Oligophrenin-1 GN=OPHN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: oligophrenin-1-like [Odobenus rosmarus divergens]
ENSG00000079616(KIF22)	--	37.76214224	1672	33.48731977	1499	36.78224319	1656	29.57069175	1312	29.76681786	1310	27.81661677	1193	0.790648424	-0.38024381	normal	0.960379363	-0.215627216	normal	0.417411569	-0.480880282	normal	0.022495042	-0.360790804	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10403|0|pps:100975606|KIF22; kinesin family member 22; K10403 kinesin family member 22 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain;; Helix-hairpin-helix motif	Kinesin-like protein KIF22 GN=KIF22 OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF22 isoform 2 [Dasypus novemcinctus]
ENSG00000079689(SCGN)	--	0	0	0	0	0	0	0.045553896	1	0.089127339	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain;; EF-hand domain pair;; EF hand;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Secretagogin GN=SCGN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: secretagogin [Galeopterus variegatus]
ENSG00000079691(CARMIL1)	--	6.921147404	809	5.998215383	696	7.048726215	796	6.953092764	807	7.567969834	878	7.449320002	870	0.976588961	-0.034337998	normal	0.884442031	0.313100191	normal	0.97113582	0.119737871	normal	0.579236144	0.13025925	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[N]	Cell motility	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 16A GN=LRRC16A OS=Homo sapiens (Human) PE=1 SV=1	N	Cell motility	PREDICTED: leucine-rich repeat-containing protein 16A isoform 1 [Ceratotherium simum simum]
ENSG00000079739(PGM1)	--	33.64564477	1548	35.60640783	1656	32.45410971	1503	37.31751201	1721	35.5727881	1624	30.43482607	1398	0.979942013	0.121894589	normal	0.983868507	-0.04953192	normal	0.979316014	-0.112654531	normal	0.977448148	-0.010923984	normal	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: intramolecular transferase activity, phosphotransferases (GO:0016868);; Biological Process: organic substance metabolic process (GO:0071704);; "	"K01835|0|hsa:5236|PGM1, CDG1T, GSD14; phosphoglucomutase 1 (EC:5.4.2.2); K01835 phosphoglucomutase [EC:5.4.2.2] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Galactose metabolism (ko00052);; Purine metabolism (ko00230);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	"Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II;; Phosphoglucomutase/phosphomannomutase, C-terminal domain"	Phosphoglucomutase-1 GN=PGM1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: phosphoglucomutase-1 isoform X1 [Camelus ferus] 
ENSG00000079785(DDX1)	--	57.76168353	2941	62.81078693	3206	59.1830941	2999	47.36615271	2452	48.98798699	2541	41.29964959	2113	0.942507788	-0.29301214	normal	0.885842535	-0.35661518	normal	0.310010819	-0.513170281	normal	0.011976483	-0.385732812	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; 	"K13177|0|hsa:1653|DDX1, DBP-RB, UKVH5d; DEAD (Asp-Glu-Ala-Asp) box helicase 1 (EC:3.6.4.13); K13177 ATP-dependent RNA helicase DDX1 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; SPRY domain;; Helicase conserved C-terminal domain	ATP-dependent RNA helicase DDX1 GN=DDX1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX1 [Panthera tigris altaica]
ENSG00000079805(DNM2)	--	29.95672324	2182	28.0083279	1989	27.76970334	2179	26.42832376	1879	30.36285887	2142	25.7232471	1938	0.957879804	-0.246331162	normal	0.984860933	0.08542605	normal	0.976248238	-0.177258539	normal	0.599009716	-0.112623463	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K01528|0|hsa:1785|DNM2, CMT2M, CMTDI1, CMTDIB, DI-CMTB, DYN2, DYNII, LCCS5; dynamin 2 (EC:3.6.5.5); K01528 dynamin GTPase [EC:3.6.5.5] (A)"	Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Bacterial invasion of epithelial cells (ko05100)	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Dynamin central region;; Dynamin family;; Dynamin GTPase effector domain;; PH domain	Dynamin-2 GN=DNM2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: dynamin-2 isoform X1 [Pteropus alecto]
ENSG00000079819(EPB41L2)	--	14.06062025	1388	13.31711317	1297	14.05703067	1367	30.56051801	3053	28.43442119	2814	18.43394142	1816	3.91E-09	1.105542296	up	1.27E-08	1.095129453	up	0.739792069	0.401073318	normal	0.007792383	0.90049482	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: cytoskeleton (GO:0005856);; Molecular Function: cytoskeletal protein binding (GO:0008092);; Biological Process: cortical actin cytoskeleton organization (GO:0030866);; 	K06107|0|pps:100970629|EPB41L2; erythrocyte membrane protein band 4.1-like 2; K06107 erythrocyte membrane protein band 4.1 (A)	Tight junction (ko04530)	[R]	General function prediction only	4.1 protein C-terminal domain (CTD);; SAB domain;; FERM N-terminal domain;; FERM C-terminal PH-like domain;; FERM central domain;; FERM adjacent (FA)	Band 4.1-like protein 2 GN=EPB41L2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: band 4.1-like protein 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000079841(RIMS1)	--	0	0	0.020960789	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K15291|0|pps:100985164|RIMS1; regulating synaptic membrane exocytosis 1; K15291 regulating synaptic membrane exocytosis protein 1 (A)	Synaptic vesicle cycle (ko04721);; Retrograde endocannabinoid signaling (ko04723)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; PDZ domain (Also known as DHR or GLGF);; FYVE-type zinc finger	Regulating synaptic membrane exocytosis protein 1 GN=RIMS1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: regulating synaptic membrane exocytosis protein 2-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000079931(MOXD1)	--	4.111532857	198	3.712170921	181	4.769278537	233	6.685809554	325	6.496187261	311	5.314889813	248	0.079266288	0.679950626	normal	0.029227219	0.754633365	normal	0.964402106	0.081207767	normal	0.042378306	0.508972038	normal	--	--	"Molecular Function: monooxygenase activity (GO:0004497);; Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen (GO:0016715);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	[E]	Amino acid transport and metabolism	"Copper type II ascorbate-dependent monooxygenase, N-terminal domain;; Copper type II ascorbate-dependent monooxygenase, C-terminal domain;; DOMON domain"	DBH-like monooxygenase protein 1 (Precursor) GN=MOXD1 OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: DBH-like monooxygenase protein 1 [Tupaia chinensis]
ENSG00000079950(STX7)	--	10.385362	625	11.34102217	659	11.666774	664	11.75954412	823	11.62573507	731	11.57180755	816	0.79985386	0.365419079	normal	0.967031269	0.127887647	normal	0.905739343	0.288500759	normal	0.183394884	0.261675626	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: membrane (GO:0016020);; 	K08488|3.87956e-150|pps:100975962|STX7; syntaxin 7; K08488 syntaxin 7 (A)	SNARE interactions in vesicular transport (ko04130);; Phagosome (ko04145)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Syntaxin-like protein;; SNARE domain;; Syntaxin	Syntaxin-7 GN=STX7 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-7 isoform X1 [Tupaia chinensis] 
ENSG00000079974(RABL2B)	--	6.52358057	285	6.603886595	298	7.188875519	303	6.688918598	287	7.736377717	315	8.512948151	366	0.967409745	-0.020632606	normal	0.965487611	0.058325038	normal	0.920607456	0.263038247	normal	0.762719635	0.107306404	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07931|7.86532e-152|mcf:102146752|RABL2B; RAB, member of RAS oncogene family-like 2B; K07931 Rab-like protein 2 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	Rab-like protein 2B GN=RABL2B OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab-like protein 2A-like isoform X2 [Equus caballus] 
ENSG00000079999(KEAP1)	--	28.83822769	1389	29.57116584	1549	28.57874976	1446	22.80725856	1151	26.38319482	1257	30.21215782	1485	0.907982279	-0.301623857	normal	0.89268219	-0.322428892	normal	0.983556283	0.0300729	normal	0.307399659	-0.191838319	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10456|0|pps:100978540|KEAP1; kelch-like ECH-associated protein 1; K10456 kelch-like protein 19 (A)	Ubiquitin mediated proteolysis (ko04120)	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; BTB/POZ domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like ECH-associated protein 1 GN=KEAP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: kelch-like ECH-associated protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000080031(PTPRH)	--	2.4831622	228	2.498502	220	2.347353751	230	1.042550971	100	0.94275677	90	1.29091882	122	1.85E-05	-1.207221124	down	4.92E-06	-1.296525718	down	0.004866763	-0.914647788	normal	1.69E-05	-1.140323109	down	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18034|0|ptr:469013|PTPRH; protein tyrosine phosphatase, receptor type, H; K18034 receptor-type tyrosine-protein phosphatase H [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Fibronectin type III domain;; Interferon-alpha/beta receptor, fibronectin type III"	Receptor-type tyrosine-protein phosphatase H (Precursor) GN=PTPRH OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase H [Dasypus novemcinctus]
ENSG00000080166(DCT)	--	0.01201157	1	0.012004003	1	0.0959971	7	0.035810045	3	0.02203346	0	0.011914219	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; 	"K01827|0|hsa:1638|DCT, TRP-2, TYRP2; dopachrome tautomerase (EC:5.3.3.12); K01827 dopachrome tautomerase [EC:5.3.3.12] (A)"	Tyrosine metabolism (ko00350);; Melanogenesis (ko04916)	--	--	Common central domain of tyrosinase	L-dopachrome tautomerase (Precursor) GN=DCT OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: L-dopachrome tautomerase isoform 2 [Equus caballus]
ENSG00000080189(SLC35C2)	--	23.0590314	854	24.81459592	905	16.35233368	646	21.1978619	790	22.0067241	811	26.9566699	984	0.967624504	-0.142948185	normal	0.960849535	-0.17932569	normal	0.074793728	0.59769089	normal	0.823286826	0.083052203	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	--	"K15280|0|ggo:101127873|SLC35C2; solute carrier family 35 member C2; K15280 solute carrier family 35, member C2 (A)"	--	[S]	Function unknown	Triose-phosphate Transporter family;; UAA transporter family;; EamA-like transporter family	Solute carrier family 35 member C2 GN=SLC35C2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	solute carrier family 35 member C2 [Camelus ferus]
ENSG00000080200(CRYBG3)	--	3.634242905	802	3.868791	846	3.68831	795	3.601476	795	3.258451	716	3.373992	743	0.976161244	-0.043396137	normal	0.926819453	-0.261615608	normal	0.971641266	-0.105676108	normal	0.554371799	-0.13767259	normal	--	--	--	--	--	--	--	Beta/Gamma crystallin;; Ricin-type beta-trefoil lectin domain;; Ricin-type beta-trefoil lectin domain-like	Very large A-kinase anchor protein GN=CRYBG3 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	"PREDICTED: beta/gamma crystallin domain-containing protein 3, partial [Galeopterus variegatus]"
ENSG00000080224(EPHA6)	--	0.798735875	25	0.40565035	8	0.388620572	8	2.150529307	56	1.146078994	41	1.662808201	65	0.355710235	1.08697214	normal	0.003212439	2.140674042	up	6.53E-08	2.798218584	up	9.86E-05	1.9605912	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05107|0|hsa:285220|EPHA6, EHK-2, EHK2, EK12, EPA6, HEK12, PRO57066; EPH receptor A6 (EC:2.7.10.1); K05107 Eph receptor A6 [EC:2.7.10.1] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Ephrin type-A receptor 6 (Precursor) GN=EPHA6 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 6 [Odobenus rosmarus divergens]
ENSG00000080293(SCTR)	--	0	0	0	0	0	0	0.036115221	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04588|0|hsa:6344|SCTR, SR; secretin receptor; K04588 secretin receptor (A)"	Neuroactive ligand-receptor interaction (ko04080);; Pancreatic secretion (ko04972);; Bile secretion (ko04976)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Secretin receptor (Precursor) GN=SCTR OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	secretin receptor precursor [Sus scrofa]
ENSG00000080298(RFX3)	--	2.677439017	202	2.435512448	221	2.49792941	226	3.497081566	286	1.534920982	166	2.452401178	242	0.660660025	0.467824095	normal	0.784853708	-0.430875107	normal	0.963757009	0.089811968	normal	0.883493494	0.074841911	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09173|0|hsa:5991|RFX3; regulatory factor X, 3 (influences HLA class II expression); K09173 regulatory factor X 1/2/3 (A)"	--	[K]	Transcription	RFX1 transcription activation region;; RFX DNA-binding domain	Transcription factor RFX3 GN=RFX3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor RFX3 [Balaenoptera acutorostrata scammoni]
ENSG00000080345(RIF1)	--	16.62188959	3221	20.37088576	3812	18.32392935	3450	11.12075316	2271	12.23254413	2454	11.4808295	2215	0.225550396	-0.534707728	normal	0.020501483	-0.656512017	normal	0.020256885	-0.647224057	normal	1.23E-05	-0.61632677	normal	--	--	--	K11138|0|hsa:55183|RIF1; replication timing regulatory factor 1; K11138 telomere-associated protein RIF1 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	--	--	Rap1-interacting factor 1 N terminal	Telomere-associated protein RIF1 GN=RIF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: telomere-associated protein RIF1 isoform 1 [Orcinus orca]
ENSG00000080371(RAB21)	--	5.327140293	1255	6.479388057	1528	5.322814443	1228	7.0597384	1681	6.3998996	1507	6.365686837	1503	0.764116453	0.390385893	normal	0.983261962	-0.041350474	normal	0.926428897	0.28292756	normal	0.264835604	0.204112355	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07890|6.11265e-148|cjc:100401527|RAB21; RAB21, member RAS oncogene family; K07890 Ras-related protein Rab-21 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-21 (Precursor) GN=RAB21 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-21 [Odobenus rosmarus divergens] 
ENSG00000080493(SLC4A4)	--	1.868199606	253	2.02921973	269	2.482581	316	3.999600093	538	5.19387848	676	4.659127941	601	4.11E-06	1.053152765	up	7.15E-10	1.303210223	up	0.000102979	0.915916946	normal	5.25E-10	1.094508951	up	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13575|0|mcf:102136348|SLC4A4; solute carrier family 4 (sodium bicarbonate cotransporter), member 4; K13575 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 (A)"	Proximal tubule bicarbonate reclamation (ko04964);; Pancreatic secretion (ko04972);; Bile secretion (ko04976)	[P]	Inorganic ion transport and metabolism	"HCO3- transporter family;; Band 3 cytoplasmic domain;; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2"	Electrogenic sodium bicarbonate cotransporter 1 GN=SLC4A4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: electrogenic sodium bicarbonate cotransporter 1 isoform X3 [Ursus maritimus]
ENSG00000080503(SMARCA2)	--	10.47412181	942	8.923506215	827	12.20947724	924	18.30899857	1814	16.94997533	1730	15.67867666	1627	9.52E-06	0.913451602	normal	1.94E-07	1.042039978	up	0.000294857	0.806949737	normal	2.26E-11	0.919821359	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on acid anhydrides (GO:0016817);; Molecular Function: histone binding (GO:0042393);; "	"K11647|0|hsa:6595|SMARCA2, BAF190, BRM, NCBRS, SNF2, SNF2L2, SNF2LA, SWI2, Sth1p, hBRM, hSNF2a; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; K11647 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-] (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	"SNF2 family N-terminal domain;; Bromodomain;; BRK domain;; Snf2-ATP coupling, chromatin remodelling complex;; HSA;; Helicase conserved C-terminal domain;; QLQ"	Probable global transcription activator SNF2L2 GN=SMARCA2 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: probable global transcription activator SNF2L2 isoform X1 [Condylura cristata]
ENSG00000080511(RDH8)	--	0	0	0	0	0	0	0	0	0	0	0.131930181	1	--	--	--	--	--	--	--	--	--	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K11150|0|hsa:50700|RDH8, PRRDH, SDR28C2; retinol dehydrogenase 8 (all-trans) (EC:1.1.1.300); K11150 retinol dehydrogenase 8 [EC:1.1.1.-] (A)"	Retinol metabolism (ko00830)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase	Retinol dehydrogenase 8 GN=RDH8 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: retinol dehydrogenase 8 [Lipotes vexillifer]
ENSG00000080546(SESN1)	--	4.921488722	204	7.46767059	324	7.525046379	321	6.80350231	290	7.827042383	324	10.33127246	431	0.64230922	0.473646165	normal	0.967116129	-0.021327014	normal	0.718628701	0.415129484	normal	0.544061621	0.279937587	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of response to reactive oxygen species (GO:1901031);; 	K10141|0|pps:100974358|SESN1; sestrin 1; K10141 sestrin (A)	p53 signaling pathway (ko04115)	[S]	Function unknown	PA26 p53-induced protein (sestrin)	Sestrin-1 GN=SESN1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: sestrin-1 isoform X1 [Felis catus]
ENSG00000080561(MID2)	--	4.117741	378	3.7264948	331	2.826660326	301	3.89749857	330	3.27287272	328	3.493424	299	0.937099958	-0.225769352	normal	0.966905471	-0.034404056	normal	0.967747393	-0.017819616	normal	0.778219434	-0.099479993	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10647|0|hsa:11043|MID2, FXY2, MRX101, RNF60, TRIM1; midline 2; K10647 midline 2 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Fibronectin type III domain"	Probable E3 ubiquitin-protein ligase MID2 GN=MID2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase MID2 isoform X1 [Equus przewalskii]
ENSG00000080572(PIH1D3)	--	0.039875	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	pre-RNA processing PIH1/Nop17	Protein PIH1D3 GN=PIH1D3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein PIH1D3 isoform X3 [Canis lupus familiaris] 
ENSG00000080573(COL5A3)	--	0.00661241	1	0.0254188	4	0	0	0.0198287	3	0.0194224	2	0.0261949	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; 	"K06236|0|hsa:50509|COL5A3; collagen, type V, alpha 3; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; Laminin G domain	Collagen alpha-3(V) chain (Precursor) GN=COL5A3 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	"PREDICTED: collagen alpha-3(V) chain, partial [Balaenoptera acutorostrata scammoni]"
ENSG00000080603(SRCAP)	--	32.21854825	3918	33.25333731	4318	34.023648	4286	37.08958175	3808	36.74213776	4356	33.400557	4497	0.991059661	-0.071887585	normal	0.992391024	-0.008782785	normal	0.992117321	0.061018572	normal	0.988196733	-0.00468356	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; 	"K11661|0|hsa:10847|SRCAP, DOMO1, EAF1, FLHS, SWR1; Snf2-related CREBBP activator protein; K11661 helicase SRCAP [EC:3.6.4.-] (A)"	--	[R]	General function prediction only	SNF2 family N-terminal domain;; HSA;; Helicase conserved C-terminal domain	Helicase SRCAP GN=SRCAP OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: Snf2-related CREBBP activator protein [Tursiops truncatus]
ENSG00000080608(PUM3)	--	25.28698	1273	22.77073	1139	27.32365508	1369	24.1913992	1213	26.13341	1290	23.542791	1169	0.978329711	-0.100361021	normal	0.970811242	0.157979571	normal	0.950821182	-0.235856695	normal	0.804262495	-0.063202156	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K14844|0|hsa:9933|HA-8, HLA-HA8, PEN, PUF6, XTP5, hPUF-A; KIAA0020; K14844 pumilio homology domain family member 6 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	CPL (NUC119) domain	Pumilio domain-containing protein KIAA0020 GN=KIAA0020 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: pumilio domain-containing protein KIAA0020 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000080644(CHRNA3)	--	0.46886139	24	0.371394124	19	0.485056648	24	0.595422463	31	0.877031	45	0.611339519	32	0.981145161	0.320321854	normal	0.446219495	1.160835174	normal	0.977337246	0.385639283	normal	0.312281383	0.668132571	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04805|0|hsa:1136|CHRNA3, LNCR2, NACHRA3, PAOD2; cholinergic receptor, nicotinic, alpha 3 (neuronal); K04805 nicotinic acetylcholine receptor alpha-3 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Neuronal acetylcholine receptor subunit alpha-3 (Precursor) GN=CHRNA3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: neuronal acetylcholine receptor subunit alpha-3 [Ceratotherium simum simum]
ENSG00000080709(KCNN2)	--	0.065564241	3	0	0	0.110487536	2	0.345563475	18	0.349417947	13	0.180651881	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calmodulin binding (GO:0005516);; Biological Process: potassium ion transport (GO:0006813);; Molecular Function: calcium-activated potassium channel activity (GO:0015269);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: small conductance calcium-activated potassium channel activity (GO:0016286);; 	"K04943|0|mcf:102135203|KCNN2; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2; K04943 potassium intermediate/small conductance calcium-activated channel subfamily N member 2 (A)"	Serotonergic synapse (ko04726);; Insulin secretion (ko04911);; Bile secretion (ko04976)	[P]	Inorganic ion transport and metabolism	Calcium-activated SK potassium channel;; Calmodulin binding domain;; Ion channel	Small conductance calcium-activated potassium channel protein 2 GN=KCNN2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: small conductance calcium-activated potassium channel protein 2-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000080802(CNOT4)	--	6.3537153	387	7.984780506	436	6.242652554	374	7.5788105	461	7.726390944	451	7.260356941	449	0.939349442	0.220797	normal	0.969516968	0.027279707	normal	0.924243273	0.254445509	normal	0.550034014	0.163780174	normal	[K]	Transcription	Molecular Function: nucleic acid binding (GO:0003676);; 	"K10643|0|mcf:102135531|CNOT4; CCR4-NOT transcription complex, subunit 4; K10643 CCR4-NOT transcription complex subunit 4 [EC:6.3.2.19] (A)"	RNA degradation (ko03018)	[K]	Transcription	"RING/Ubox like zinc-binding domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	CCR4-NOT transcription complex subunit 4 GN=CNOT4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 4 isoform X1 [Camelus ferus] 
ENSG00000080815(PSEN1)	--	32.00389545	1610	34.83285757	1814	31.04104364	1651	31.39903393	1892	33.25920551	1915	37.82087424	2080	0.968497557	0.201841312	normal	0.984976616	0.056697373	normal	0.899731993	0.324686439	normal	0.296544917	0.193125096	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein processing (GO:0016485);; 	K04505|0|ptr:739740|PSEN1; presenilin 1; K04505 presenilin 1 [EC:3.4.23.-] (A)	Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; Neurotrophin signaling pathway (ko04722);; Alzheimer's disease (ko05010)	[T]	Signal transduction mechanisms	Presenilin	Presenilin-1 CTF12 GN=PSEN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: presenilin-1-like isoform X1 [Tupaia chinensis] 
ENSG00000080819(CPOX)	--	20.0213	914	19.4177	908	22.2956	1030	24.7072	1145	21.3112	967	21.2112	968	0.908501225	0.293807247	normal	0.976439073	0.069285207	normal	0.975794649	-0.097708816	normal	0.715135352	0.089426877	normal	--	--	Molecular Function: coproporphyrinogen oxidase activity (GO:0004109);; Biological Process: porphyrin-containing compound biosynthetic process (GO:0006779);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00228|0|hsa:1371|CPOX, CPO, CPX, HCP; coproporphyrinogen oxidase (EC:1.3.3.3); K00228 coproporphyrinogen III oxidase [EC:1.3.3.3] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	Coproporphyrinogen III oxidase	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (Precursor) GN=CPOX OS=Homo sapiens (Human) PE=1 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: coproporphyrinogen-III oxidase, mitochondrial [Vicugna pacos]"
ENSG00000080822(CLDND1)	--	31.1291301	903	27.44650773	828	27.37189392	804	23.759037	711	21.66853702	628	27.56483785	802	0.77985535	-0.374987647	normal	0.670402965	-0.419410103	normal	0.977018813	-0.011862366	normal	0.167037547	-0.26469717	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin tight junction;; PMP-22/EMP/MP20/Claudin family	Claudin domain-containing protein 1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: claudin domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000080823(MOK)	--	16.72828109	644	12.53046474	490	17.725812	643	12.383944	523	9.257693	380	13.6910805	544	0.857425708	-0.330205932	normal	0.773626081	-0.386849088	normal	0.929579291	-0.248866392	normal	0.268373008	-0.317304472	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08830|0|pps:100987137|MOK; MOK protein kinase; K08830 renal tumor antigen [EC:2.7.11.22] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	MAPK/MAK/MRK overlapping kinase GN=MOK OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: MAPK/MAK/MRK overlapping kinase [Ceratotherium simum simum]
ENSG00000080824(HSP90AA1)	--	618.404965	45357	553.142701	40442	760.412847	55025	626.483409	46442	551.185411	40328	444.183224	32502	0.998980275	0.003272509	normal	0.99876874	-0.025498089	normal	0.003181828	-0.767822403	normal	0.379320649	-0.261399086	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: protein folding (GO:0006457);; Biological Process: response to stress (GO:0006950);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K04079|0|pon:100173221|HSP90AA1; heat shock protein 90kDa alpha (cytosolic), class A member 1; K04079 molecular chaperone HtpG (A)"	Protein processing in endoplasmic reticulum (ko04141);; PI3K-Akt signaling pathway (ko04151);; Antigen processing and presentation (ko04612);; NOD-like receptor signaling pathway (ko04621);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Pathways in cancer (ko05200);; Prostate cancer (ko05215)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Hsp90 protein;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	Heat shock protein HSP 90-alpha GN=HSP90AA1 OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein HSP 90-alpha [Trichechus manatus latirostris]
ENSG00000080839(RBL1)	--	10.05656248	935	10.12516541	963	10.375213	964	9.69307209	895	8.65423517	824	10.1891333	885	0.974904402	-0.093753458	normal	0.938345632	-0.245900062	normal	0.971106573	-0.131431868	normal	0.465352649	-0.157529861	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of cell cycle (GO:0051726);; 	"K04681|0|hsa:5933|RBL1, CP107, PRB1, p107; retinoblastoma-like 1; K04681 retinoblastoma-like protein 1 (A)"	Cell cycle (ko04110);; TGF-beta signaling pathway (ko04350);; Viral carcinogenesis (ko05203)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Retinoblastoma-associated protein A domain;; Retinoblastoma-associated protein B domain;; Domain of unknown function (DUF3452);; Rb C-terminal domain	Retinoblastoma-like protein 1 GN=RBL1 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: retinoblastoma-like protein 1 [Leptonychotes weddellii]
ENSG00000080845(DLGAP4)	--	17.02945328	1085	17.7479397	1071	18.76907791	1173	25.04547919	1558	19.0775387	1285	20.23161109	1340	0.372119029	0.49058541	normal	0.946975815	0.241072201	normal	0.966812991	0.183517032	normal	0.064462578	0.307884065	normal	--	--	Biological Process: signaling (GO:0023052);; 	--	--	[T]	Signal transduction mechanisms	Guanylate-kinase-associated protein (GKAP) protein	Disks large-associated protein 4 GN=DLGAP4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: disks large-associated protein 4 [Camelus dromedarius]
ENSG00000080854(IGSF9B)	--	0.574997917	91	0.44528969	79	0.527087088	80	0.531560922	65	0.65051363	57	0.636854989	78	0.871811441	-0.506097021	normal	0.903256808	-0.481417797	normal	0.97297241	-0.043975405	normal	0.516566157	-0.342702319	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Fibronectin type III domain;; CD80-like C2-set immunoglobulin domain	Protein turtle homolog B (Precursor) GN=IGSF9B OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein turtle homolog B [Leptonychotes weddellii]
ENSG00000080910(CFHR2)	--	0.138795	3	0	0	0.0464287	0	0.0917733	2	0.541116359	11	0.05921158	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sushi domain (SCR repeat)	Complement factor H-related protein 2 (Precursor) GN=CFHR2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: complement factor H-related protein 2-like [Panthera tigris altaica]
ENSG00000080986(NDC80)	--	7.150440816	287	7.126861822	276	6.805031514	254	9.059880762	325	6.859488167	266	7.117303261	262	0.957189499	0.147812806	normal	0.964007316	-0.074254106	normal	0.966748797	0.036234451	normal	0.926926189	0.040127534	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	"K11547|0|hsa:10403|NDC80, HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80; NDC80 kinetochore complex component; K11547 kinetochore protein NDC80 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	HEC/Ndc80p family	Kinetochore protein NDC80 homolog GN=NDC80 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: kinetochore protein NDC80 homolog isoform X2 [Mustela putorius furo] 
ENSG00000081014(AP4E1)	--	7.259628	774	7.308446	783	6.753514	709	10.1673	1091	8.903087	947	8.544437	910	0.486660787	0.46363486	normal	0.934204057	0.252481593	normal	0.828863812	0.351126764	normal	0.036824145	0.357646914	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; 	"K12400|0|pps:100983845|AP4E1; adaptor-related protein complex 4, epsilon 1 subunit; K12400 AP-4 complex subunit epsilon-1 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptin N terminal region;; Adaptin AP4 complex epsilon appendage platform	AP-4 complex subunit epsilon-1 GN=AP4E1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-4 complex subunit epsilon-1 isoform X3 [Canis lupus familiaris]
ENSG00000081019(RSBN1)	--	2.11928136	193	2.50247724	199	2.47476911	241	2.270849903	200	2.44763436	225	2.56339834	239	0.966877827	0.020407302	normal	0.955426619	0.15462443	normal	0.966950188	-0.020186768	normal	0.922328036	0.048719585	normal	--	--	--	--	--	[S]	Function unknown	--	Round spermatid basic protein 1 GN=RSBN1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: round spermatid basic protein 1 [Ceratotherium simum simum]
ENSG00000081026(MAGI3)	--	2.792282823	473	2.3051959	388	2.88040545	472	4.166294839	706	3.8238928	633	3.5183517	600	0.215131891	0.545536662	normal	0.025170583	0.682619828	normal	0.849504818	0.336924565	normal	0.004183859	0.519142161	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K06112|0|hsa:260425|MAGI3, MAGI-3, dJ730K3.2; membrane associated guanylate kinase, WW and PDZ domain containing 3; K06112 membrane-associated guanylate kinase-related (A)"	Rap1 signaling pathway (ko04015);; Tight junction (ko04530)	[R]	General function prediction only	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; WW domain;; Guanylate kinase;; Tricorn protease PDZ domain	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 GN=MAGI3 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform 1 [Orcinus orca]"
ENSG00000081041(CXCL2)	--	16.492687	271	17.203271	284	9.172782	151	60.838632	1015	38.771855	615	61.78335	994	0	1.86841868	up	1.08E-06	1.089233272	up	0	2.698269597	up	7.07E-06	1.871574795	up	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K05505|9.08166e-47|hsa:2920|CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2; chemokine (C-X-C motif) ligand 2; K05505 C-X-C motif chemokine 1/2/3 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668);; Salmonella infection (ko05132);; Legionellosis (ko05134)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	GRO-beta(5-73) (Precursor) GN=CXCL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: c-X-C motif chemokine 2-like [Ceratotherium simum simum]
ENSG00000081051(AFP)	--	0	0	0.056667746	2	0.045093978	1	0.2049156	9	0.196441734	8	0.044707974	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular space (GO:0005615);; 	"K16144|0|hsa:174|AFP, AFPD, FETA, HPAFP; alpha-fetoprotein; K16144 alpha-fetoprotein (A)"	Hippo signaling pathway (ko04390)	--	--	"Serum albumin family;; Vitamin D binding protein, domain III"	Alpha-fetoprotein (Precursor) GN=AFP OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: alpha-fetoprotein [Galeopterus variegatus]
ENSG00000081052(COL4A4)	--	2.889186484	484	2.74648273	487	2.078275358	384	1.5558462	269	1.958379576	346	2.0733778	376	0.000545093	-0.874452482	normal	0.398346385	-0.51267763	normal	0.96873451	-0.038511813	normal	0.038906377	-0.471899189	normal	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Cellular Component: collagen trimer (GO:0005581);; 	"K06237|0|hsa:1286|COL4A4, CA44; collagen, type IV, alpha 4; K06237 collagen, type IV, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; C-terminal tandem repeated domain in type 4 procollagen	Collagen alpha-4(IV) chain (Precursor) GN=COL4A4 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: collagen alpha-4(IV) chain [Ceratotherium simum simum]
ENSG00000081059(TCF7)	--	5.726442791	304	3.058873181	186	5.420841312	241	4.08700388	201	6.666895093	370	2.372591962	143	0.182966013	-0.623800659	normal	0.000264883	0.965128235	normal	0.052908658	-0.755087882	normal	0.965475915	-0.055390245	normal	--	--	--	"K02620|0|cjc:100399154|TCF7; transcription factor 7 (T-cell specific, HMG-box); K02620 transcription factor 7 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Melanogenesis (ko04916);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Basal cell carcinoma (ko05217);; Acute myeloid leukemia (ko05221);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[K]	Transcription	N-terminal CTNNB1 binding;; HMG (high mobility group) box;; HMG-box domain	Transcription factor 7 GN=TCF7 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor 7 isoform X1 [Bos taurus]
ENSG00000081087(OSTM1)	--	18.76690966	1234	23.08701259	1509	20.93141056	1347	15.93570856	1058	14.21900883	937	20.48650907	1352	0.940301068	-0.252495085	normal	0.005895487	-0.707988949	normal	0.982960719	-0.002942843	normal	0.214389274	-0.309805883	normal	--	--	--	--	--	[S]	Function unknown	Osteopetrosis-associated transmembrane protein 1 precursor	Osteopetrosis-associated transmembrane protein 1 (Precursor) GN=OSTM1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: osteopetrosis-associated transmembrane protein 1 [Pteropus alecto] 
ENSG00000081138(CDH7)	--	0.017386302	2	0.035472155	2	0.035025978	1	0.247837963	24	0.277587625	22	0.414366803	40	0.015981967	2.828981796	normal	0.039301115	2.726813596	normal	2.43E-07	4.040821639	up	6.57E-07	4.083609705	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06799|0|pps:100989662|CDH7; cadherin 7, type 2; K06799 cadherin 7, type 2 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin-like	Cadherin-7 (Precursor) GN=CDH7 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: cadherin-7 [Tupaia chinensis] 
ENSG00000081148(IMPG2)	--	0.0143255	2	0.0286282	4	0.0143457	1	0.0427598	6	0.0069573	0	0.0142574	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SEA domain	Interphotoreceptor matrix proteoglycan 2 (Precursor) GN=IMPG2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: interphotoreceptor matrix proteoglycan 2 [Ceratotherium simum simum]
ENSG00000081154(PCNP)	--	76.17978	2665	78.63381	2755	84.89813	2895	77.00029	2720	67.56413	2338	73.02204	2563	0.989414392	-0.001360369	normal	0.959402731	-0.258049981	normal	0.979372467	-0.183919134	normal	0.465069267	-0.1470562	normal	--	--	Biological Process: protein ubiquitination (GO:0016567);; 	--	--	--	--	"PEST, proteolytic signal-containing nuclear protein family"	PEST proteolytic signal-containing nuclear protein GN=PCNP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: PEST proteolytic signal-containing nuclear protein [Myotis lucifugus] 
ENSG00000081177(EXD2)	--	10.88887377	750	11.31109858	747	9.708795709	646	12.76949648	834	10.91423987	706	13.80183899	923	0.970038134	0.122087284	normal	0.97059495	-0.10265281	normal	0.324945898	0.505509945	normal	0.408150727	0.179570964	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	--	--	[R]	General function prediction only	3'-5' exonuclease	Exonuclease 3'-5' domain-containing protein 2 GN=EXD2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: exonuclease 3'-5' domain-containing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000081181(ARG2)	--	0.355505	12	0.292055	10	0.348169	11	0.409077	14	0.574887	19	0.672559	23	--	--	--	--	--	--	0.941876954	0.962624955	normal	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: metal ion binding (GO:0046872);; 	K01476|0|pps:100974594|ARG2; arginase 2; K01476 arginase [EC:3.5.3.1] (A)	Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230);; Amoebiasis (ko05146)	[E]	Amino acid transport and metabolism	Arginase family	"Arginase-2, mitochondrial (Precursor) GN=ARG2 OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: arginase-2, mitochondrial [Tupaia chinensis]"
ENSG00000081189(MEF2C)	--	0.018823036	2	0.028415698	3	0.075704819	7	0.00935703	1	0.009091782	0	0.065264339	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein dimerization activity (GO:0046983);; 	K04454|0|ptr:461760|MEF2C; myocyte enhancer factor 2C; K04454 MADS-box transcription enhancer factor 2C (A)	MAPK signaling pathway (ko04010);; cGMP-PKG signaling pathway (ko04022);; Oxytocin signaling pathway (ko04921);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Holliday junction regulator protein family C-terminal repeat;; SRF-type transcription factor (DNA-binding and dimerisation domain)	Myocyte-specific enhancer factor 2C GN=MEF2C OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myocyte-specific enhancer factor 2C-like isoform X2 [Chrysochloris asiatica]
ENSG00000081237(PTPRC)	--	0	0	0	0	0	0	0.02293721	2	0.02236658	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; Biological Process: T cell receptor signaling pathway (GO:0050852);; 	"K06478|0|pps:100990077|PTPRC; protein tyrosine phosphatase, receptor type, C; K06478 receptor-type tyrosine-protein phosphatase C [EC:3.1.3.48] (A)"	Cell adhesion molecules (CAMs) (ko04514);; T cell receptor signaling pathway (ko04660);; Fc gamma R-mediated phagocytosis (ko04666);; Primary immunodeficiency (ko05340)	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase;; Leukocyte receptor CD45;; Protein tyrosine phosphatase N terminal;; Fibronectin type III domain;; Inositol hexakisphosphate;; Tyrosine phosphatase family	Receptor-type tyrosine-protein phosphatase C (Precursor) GN=PTPRC OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase C isoform X1 [Oryctolagus cuniculus] 
ENSG00000081277(PKP1)	--	0	0	0	0	0	0	0	0	0	0	0.00880352	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10387|0|hsa:5317|PKP1, B6P; plakophilin 1; K10387 plakophilin 1 (A)"	--	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat;; HEAT repeats	Plakophilin-1 GN=PKP1 OS=Homo sapiens (Human) PE=1 SV=2	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: plakophilin-1 isoform X1 [Chrysochloris asiatica]
ENSG00000081307(UBA5)	--	10.017335	478	8.6141861	491	11.615104	518	12.92424748	571	13.221712	622	12.381232	624	0.939232989	0.224985549	normal	0.873624858	0.318890593	normal	0.922985233	0.259611001	normal	0.20998355	0.268372139	normal	--	--	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	"K12164|0|hsa:79876|UBA5, THIFP1, UBE1DC1; ubiquitin-like modifier activating enzyme 5; K12164 ubiquitin-like modifier-activating enzyme 5 (A)"	--	[H]	Coenzyme transport and metabolism	ThiF family	Ubiquitin-like modifier-activating enzyme 5 GN=UBA5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like modifier-activating enzyme 5 [Sus scrofa]
ENSG00000081320(STK17B)	--	6.235367866	459	5.756595179	381	5.925141009	436	4.1627772	319	5.798705315	439	3.749049593	284	0.258939901	-0.553533822	normal	0.950562484	0.182328744	normal	0.107188086	-0.624025851	normal	0.277716986	-0.313462683	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08804|0|hsa:9262|STK17B, DRAK2; serine/threonine kinase 17b (EC:2.7.11.1); K08804 serine/threonine kinase 17 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 17B GN=STK17B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 17B [Galeopterus variegatus] 
ENSG00000081377(CDC14B)	--	8.025793274	698	8.744032955	706	8.178191253	693	7.24477766	652	7.210975433	664	6.188162847	572	0.967021028	-0.128893688	normal	0.969094063	-0.109669215	normal	0.906705017	-0.284447305	normal	0.451858831	-0.173025442	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K06639|0|pon:100436806|CDC14B; cell division cycle 14B; K06639 cell division cycle 14 [EC:3.1.3.16 3.1.3.48] (A)	Cell cycle (ko04110)	[V]	Defense mechanisms	"Dual specificity protein phosphatase, N-terminal half;; Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase;; Inositol hexakisphosphate"	Dual specificity protein phosphatase CDC14B GN=CDC14B OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase CDC14B isoform X2 [Loxodonta africana]
ENSG00000081386(ZNF510)	--	5.54093148	439	4.688774944	466	4.683472693	432	3.694469734	452	4.958824112	449	3.896969441	460	0.970569655	0.011230833	normal	0.967586661	-0.074793769	normal	0.967638098	0.082032778	normal	0.996314771	0.004434202	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:22869|ZNF510; zinc finger protein 510; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 510 GN=ZNF510 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 510 [Ceratotherium simum simum]
ENSG00000081479(LRP2)	--	0.018955462	6	0.013126446	4	0.037994926	2	0.013120558	4	0.012818547	2	0.0126243	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	"K06233|0|hsa:4036|LRP2, DBS, GP330; low density lipoprotein receptor-related protein 2; K06233 low density lipoprotein-related protein 2 (A)"	Hedgehog signaling pathway (ko04340);; Thyroid hormone synthesis (ko04918)	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; SMP-30/Gluconolaconase/LRE-like region;; Arylesterase	Low-density lipoprotein receptor-related protein 2 (Precursor) GN=LRP2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 2 [Tupaia chinensis]
ENSG00000081665(ZNF506)	--	0.480359153	19	1.122769452	20	1.32500981	16	1.117781211	31	0.530979499	29	0.594819697	20	0.961711403	0.634918595	normal	0.9740305	0.484086983	normal	0.987663316	0.289151398	normal	0.514020745	0.517835177	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:440515|ZNF506; zinc finger protein 506; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; C1-like domain"	Zinc finger protein 506 GN=ZNF506 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000081692(JMJD4)	--	9.292363	407	8.220363	372	8.2963765	375	10.018977	443	10.5878416	461	9.58254	422	0.966310546	0.091115902	normal	0.903268886	0.286987834	normal	0.955995692	0.161446892	normal	0.50958582	0.179091536	normal	--	--	--	--	--	[BT]	Chromatin structure and dynamics;; Signal transduction mechanisms	"Cupin-like domain;; JmjC domain, hydroxylase"	JmjC domain-containing protein 4 GN=JMJD4 OS=Homo sapiens (Human) PE=1 SV=2	BT	Chromatin structure and dynamics;; Signal transduction mechanisms	PREDICTED: jmjC domain-containing protein 4 isoform X1 [Galeopterus variegatus]
ENSG00000081721(DUSP12)	--	19.33153	396	20.08266	421	16.77078	348	15.76774	328	19.0127	388	19.13939	392	0.893295946	-0.301349881	normal	0.959304868	-0.138671077	normal	0.955276415	0.162807936	normal	0.77952704	-0.093281838	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14819|0|ptr:458016|DUSP12; dual specificity phosphatase 12; K14819 dual specificity phosphatase 12 [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain"	Dual specificity protein phosphatase 12 GN=DUSP12 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 12 [Equus caballus] 
ENSG00000081760(AACS)	--	14.71254	945	14.70516	958	14.85385	967	19.48558	1260	18.75041	1203	22.00853	1419	0.767344813	0.383663447	normal	0.899894567	0.306679701	normal	0.174306802	0.544288498	normal	0.008361174	0.414913866	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01907|0|hsa:65985|AACS, ACSF1, SUR-5; acetoacetyl-CoA synthetase (EC:6.2.1.16); K01907 acetoacetyl-CoA synthetase [EC:6.2.1.16] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Butanoate metabolism (ko00650)"	[I]	Lipid transport and metabolism	AMP-binding enzyme	Acetoacetyl-CoA synthetase GN=AACS OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	acetoacetyl-CoA synthetase [Bos taurus] 
ENSG00000081791(KIAA0141)	--	22.98808592	1087	21.73901668	1059	21.12500966	1035	19.61720816	885	23.77963547	1026	20.64545714	993	0.870478485	-0.326921642	normal	0.977900525	-0.067001203	normal	0.978023892	-0.067955207	normal	0.472653521	-0.152296494	normal	[R]	General function prediction only	--	--	--	[MOT]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Sel1 repeat	Death ligand signal enhancer (Precursor) GN=KIAA0141 OS=Homo sapiens (Human) PE=1 SV=3	MOT	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: death ligand signal enhancer [Ceratotherium simum simum]
ENSG00000081803(CADPS2)	--	0.250964553	25	0.2247246	18	0.352053443	27	0.150715318	14	0.2574071	22	0.239920102	23	0.956291671	-0.800733041	normal	0.986292737	0.249124836	normal	0.984652679	-0.225894447	normal	0.788665466	-0.265853552	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Domain of Unknown Function (DUF1041);; PH domain	Calcium-dependent secretion activator 2 GN=CADPS2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcium-dependent secretion activator 2 isoform X5 [Equus caballus] 
ENSG00000081818(PCDHB4)	--	0.250438	15	0.133152	8	0.148047	8	0.132777	8	0.225867	13	0.181426	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56131|PCDHB4, PCDH-BETA4; protocadherin beta 4; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-4 (Precursor) GN=PCDHB4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC103550699 [Equus przewalskii]
ENSG00000081842(PCDHA6)	--	24.00360325	1932	26.13815962	2232	23.31782598	1924	24.63184445	2015	26.4828104	2081	31.49312727	2549	0.986517921	0.029829253	normal	0.98299349	-0.122400708	normal	0.777033452	0.397258993	normal	0.679075247	0.105637226	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16493|0|hsa:56142|PCDHA6, CNR2, CNRN2, CNRS2, CRNR2, PCDH-ALPHA6; protocadherin alpha 6; K16493 protocadherin alpha (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin alpha-6 (Precursor) GN=PCDHA6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin alpha-8 isoform X5 [Equus przewalskii]
ENSG00000081853(PCDHGA2)	--	19.73470922	1476	22.77011637	1716	17.90572625	1399	16.21286252	1260	18.6736421	1447	22.03176428	1573	0.941575345	-0.258809283	normal	0.94193542	-0.267154437	normal	0.973891212	0.160667391	normal	0.600767364	-0.121964634	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16495|0|hsa:56113|PCDHGA2, PCDH-GAMMA-A2; protocadherin gamma subfamily A, 2; K16495 protocadherin gamma subfamily A (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin gamma-A2 (Precursor) GN=PCDHGA2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: protocadherin gamma subfamily A, 2 [Tupaia chinensis]"
ENSG00000081870(HSPB11)	--	25.662292	271	28.152234	272	35.879247	335	30.098715	318	28.364211	284	21.779354	208	0.94620221	0.198860064	normal	0.965786561	0.040636609	normal	0.059833173	-0.691867211	normal	0.707357844	-0.138302612	normal	--	--	--	--	--	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	Putative binding domain;; F5/8 type C domain	Intraflagellar transport protein 25 homolog GN=HSPB11 OS=Homo sapiens (Human) PE=1 SV=1	DO	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein beta-11 [Camelus ferus] 
ENSG00000081913(PHLPP1)	--	4.178540092	455	4.317498778	459	4.857804	537	5.311322	611	4.561637	516	4.041833458	457	0.743557685	0.393323909	normal	0.959653745	0.146993395	normal	0.932198388	-0.240284993	normal	0.715386016	0.1047261	normal	[S]	Function unknown	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: protein binding (GO:0005515);; 	"K16340|0|hsa:23239|PHLPP1, PHLPP, PLEKHE1, SCOP; PH domain and leucine rich repeat protein phosphatase 1 (EC:3.1.3.16); K16340 PH domain and leucine-rich repeat-containing protein phosphatase [EC:3.1.3.16] (A)"	PI3K-Akt signaling pathway (ko04151)	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Protein phosphatase 2C;; Leucine Rich Repeat;; Leucine rich repeat	PH domain leucine-rich repeat-containing protein phosphatase 1 GN=PHLPP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: PH domain leucine-rich repeat-containing protein phosphatase 1, partial [Camelus dromedarius]"
ENSG00000081923(ATP8B1)	--	9.01733613	1030	12.42846	1414	10.55682129	1169	13.94280965	1508	10.74329405	1194	17.28737524	1963	0.25855372	0.518517168	normal	0.937535627	-0.265096875	normal	0.001827583	0.738748217	normal	0.404658547	0.348070152	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:5205|ATP8B1, ATPIC, BRIC, FIC1, ICP1, PFIC, PFIC1; ATPase, aminophospholipid transporter, class I, type 8B, member 1 (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase	Phospholipid-transporting ATPase IC GN=ATP8B1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IC [Oryctolagus cuniculus]
ENSG00000081985(IL12RB2)	--	0.052404228	4	0.104586317	8	0.116187292	8	0.078975891	6	0.038194041	2	0.026017557	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05064|0|ptr:469348|IL12RB2; interleukin 12 receptor, beta 2; K05064 interleukin 12 receptor beta-2 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Inflammatory bowel disease (IBD) (ko05321)	--	--	"Fibronectin type III domain;; Ig-like C2-type domain;; Interleukin-6 receptor alpha chain, binding"	Interleukin-12 receptor subunit beta-2 (Precursor) GN=IL12RB2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: interleukin-12 receptor subunit beta-2 [Balaenoptera acutorostrata scammoni]
ENSG00000082014(SMARCD3)	--	8.104807034	283	6.818889089	266	6.202887367	235	6.179660596	241	10.1463724	369	6.708109832	246	0.924732306	-0.261063234	normal	0.662031684	0.448593957	normal	0.965788209	0.057345406	normal	0.830156026	0.105588177	normal	[B]	Chromatin structure and dynamics	Molecular Function: protein binding (GO:0005515);; 	"K11650|0|pon:100446101|SMARCD3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3; K11650 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	SWIB/MDM2 domain	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 GN=SMARCD3 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 isoformX3 [Canis lupus familiaris]
ENSG00000082068(WDR70)	--	7.014080341	407	7.11798416	415	7.309961	420	7.823171365	458	9.278269888	504	8.8142068	510	0.960535597	0.138991741	normal	0.922047706	0.258031491	normal	0.914510234	0.270929897	normal	0.358420697	0.224306843	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 70 GN=WDR70 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 70 [Oryctolagus cuniculus]
ENSG00000082074(FYB)	--	3.734012468	374	3.894315918	382	4.833025959	466	2.663120336	266	1.999655304	200	3.112545117	284	0.421727316	-0.519898096	normal	0.000296458	-0.949708897	normal	0.017788527	-0.719707519	normal	0.000450498	-0.725013112	normal	--	--	--	"K17698|0|hsa:2533|FYB, ADAP, PRO0823, SLAP-130, SLAP130; FYN binding protein; K17698 FYN binding protein (A)"	Rap1 signaling pathway (ko04015)	--	--	Helically-extended SH3 domain;; Variant SH3 domain	FYN-binding protein GN=FYB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: FYN-binding protein isoform X1 [Equus caballus]
ENSG00000082126(MPP4)	--	0.090395094	4	0.088340294	4	0.288699152	12	0.04515864	2	0.042527053	1	0.067518735	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Guanylate kinase;; L27 domain;; PDZ domain (Also known as DHR or GLGF);; SH3 domain;; Variant SH3 domain	MAGUK p55 subfamily member 4 GN=MPP4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: MAGUK p55 subfamily member 4 [Galeopterus variegatus]
ENSG00000082146(STRADB)	--	24.898505	785	19.863514	648	20.850015	686	18.61361	642	19.084742	639	18.781185	590	0.871712052	-0.320257092	normal	0.973117137	-0.041506891	normal	0.941794974	-0.225249084	normal	0.358143367	-0.201031593	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K17532|0|pps:100980314|STRADB; STE20-related kinase adaptor beta; K17532 STE20-related kinase adapter protein beta (A)	AMPK signaling pathway (ko04152)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	STE20-related kinase adapter protein beta GN=STRADB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: STE20-related kinase adapter protein beta [Galeopterus variegatus]
ENSG00000082153(BZW1)	--	149.8424093	7633	150.2605261	7579	152.3907209	7518	158.3575796	8050	129.5454311	6501	102.266976	4944	0.995236019	0.045897332	normal	0.982944997	-0.242720057	normal	0.065786128	-0.612808461	normal	0.381492324	-0.244158267	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	eIF4-gamma/eIF5/eIF2-epsilon	Basic leucine zipper and W2 domain-containing protein 1 GN=BZW1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: basic leucine zipper and W2 domain-containing protein 1 isoform 1 [Dasypus novemcinctus]
ENSG00000082175(PGR)	--	0.02610065	2	0.011238544	2	0	0	0	0	0.032761319	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: steroid hormone receptor activity (GO:0003707);; Molecular Function: steroid binding (GO:0005496);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08556|0|hsa:5241|PGR, NR3C3, PR; progesterone receptor; K08556 progesterone receptor (A)"	Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914)	[T]	Signal transduction mechanisms	"Progesterone receptor;; Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Progesterone receptor GN=PGR OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	progesterone receptor [Oryctolagus cuniculus] 
ENSG00000082196(C1QTNF3)	--	0.1003305	4	0.229042896	7	0.097544287	2	0.098045	4	0.160548695	4	0.130487687	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	Complement C1q tumor necrosis factor-related protein 3 (Precursor) GN=C1QTNF3 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: complement C1q tumor necrosis factor-related protein 3 isoform 1 [Canis lupus familiaris]
ENSG00000082212(ME2)	--	32.33402088	1387	28.73682106	1203	32.8152942	1370	29.8889258	1302	27.86475224	1182	24.17232882	1041	0.977387495	-0.121931158	normal	0.980377875	-0.046773844	normal	0.714916012	-0.403984016	normal	0.324358395	-0.189605224	normal	[C]	Energy production and conversion	Molecular Function: malate dehydrogenase (decarboxylating) (NAD+) activity (GO:0004471);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00027|0|pps:100990575|ME2; malic enzyme 2, NAD(+)-dependent, mitochondrial; K00027 malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38] (A)"	Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	"Malic enzyme, NAD binding domain;; Malic enzyme, N-terminal domain"	"NAD-dependent malic enzyme, mitochondrial (Precursor) GN=ME2 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NAD-dependent malic enzyme, mitochondrial [Oryctolagus cuniculus]"
ENSG00000082213(C5orf22)	--	8.348524	459	6.755238	366	9.353999	457	8.453567	442	8.984938	468	7.622514	398	0.967374617	-0.084990102	normal	0.861024438	0.332022459	normal	0.944539141	-0.206982596	normal	0.988049318	0.00776018	normal	--	--	--	--	--	--	--	UPF0489 domain	UPF0489 protein C5orf22 GN=C5orf22 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0489 protein C5orf22 homolog [Leptonychotes weddellii]
ENSG00000082258(CCNT2)	--	9.858007971	923	9.568997657	974	10.1737985	955	6.654918001	601	6.930674549	643	6.596641624	713	0.02714885	-0.64844899	normal	0.055847344	-0.619336992	normal	0.623766435	-0.429100793	normal	0.000380613	-0.563999984	normal	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	--	K15188|0|pps:100990651|CCNT2; cyclin T2; K15188 cyclin T (A)	Transcriptional misregulation in cancer (ko05202)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-T2 GN=CCNT2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-T2 isoformX1 [Canis lupus familiaris]
ENSG00000082269(FAM135A)	--	4.819789712	398	5.966494486	489	5.189297168	445	4.9081856	426	5.086440301	400	4.945807179	419	0.967890342	0.067002709	normal	0.883186398	-0.310198314	normal	0.966241885	-0.094814412	normal	0.69050554	-0.118748405	normal	--	--	--	--	--	[S]	Function unknown	Putative serine esterase (DUF676);; Protein of unknown function (DUF3657);; PGAP1-like protein;; Lecithin:cholesterol acyltransferase	Protein FAM135A GN=FAM135A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM135A isoform X1 [Galeopterus variegatus]
ENSG00000082438(COBLL1)	--	2.552047135	217	2.545478073	214	2.48268343	230	2.065128314	186	2.537777039	196	3.10981723	227	0.934098494	-0.251300451	normal	0.956670875	-0.147097073	normal	0.966751091	-0.027053948	normal	0.72414429	-0.138680715	normal	--	--	--	--	--	--	--	Cordon-bleu ubiquitin-like domain	Cordon-bleu protein-like 1 GN=COBLL1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: COBL-like 1 isoform X3 [Equus caballus]
ENSG00000082458(DLG3)	--	2.69694835	272	2.596213834	264	2.541861243	259	2.423518645	245	2.730918651	259	2.338772352	227	0.951055423	-0.180581712	normal	0.965252415	-0.048730556	normal	0.947635722	-0.197319617	normal	0.69020665	-0.142501214	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12075|0|pon:100447431|DLG3, MPP3; discs, large homolog 3 (Drosophila); K12075 discs large protein 2/3 (A)"	Hippo signaling pathway (ko04390)	[F]	Nucleotide transport and metabolism	Guanylate kinase;; PDZ domain (Also known as DHR or GLGF);; PDZ-associated domain of NMDA receptors;; Polyubiquitination (PEST) N-terminal domain of MAGUK;; PDZ domain;; SH3 domain;; Variant SH3 domain	Disks large homolog 3 GN=DLG3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: disks large homolog 3 isoform X1 [Lipotes vexillifer]
ENSG00000082482(KCNK2)	--	0.043916075	2	0.129176707	4	0.086172242	2	0.039476266	2	0.167018227	4	0.13760053	2	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	"K04913|0|pps:100991720|KCNK2; potassium channel, subfamily K, member 2; K04913 potassium channel subfamily K member 2 (A)"	Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 2 GN=KCNK2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 2-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000082497(SERTAD4)	--	1.432606686	119	1.760302328	143	2.250325	185	2.488044	212	2.948364	244	2.733002427	228	0.047015618	0.794487887	normal	0.066637767	0.743354598	normal	0.916426478	0.291070203	normal	0.034428755	0.59341862	normal	--	--	--	--	--	--	--	SERTA motif	SERTA domain-containing protein 4 GN=SERTAD4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SERTA domain-containing protein 4 [Ceratotherium simum simum]
ENSG00000082512(TRAF5)	--	5.588117864	608	5.473330267	594	6.430075601	655	6.03597778	584	6.112436332	577	5.742385472	583	0.969996353	-0.088706465	normal	0.971008256	-0.063155021	normal	0.957230386	-0.175859826	normal	0.676089079	-0.111608288	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K09849|0|hsa:7188|TRAF5, MGC:39780, RNF84; TNF receptor-associated factor 5; K09849 TNF receptor-associated factor 5 (A)"	NF-kappa B signaling pathway (ko04064);; TNF signaling pathway (ko04668);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	"TRAF-type zinc finger;; MATH domain;; Zinc finger, C3HC4 type (RING finger)"	TNF receptor-associated factor 5 GN=TRAF5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TNF receptor-associated factor 5 [Pteropus alecto] 
ENSG00000082515(MRPL22)	--	25.056629	464	19.93071806	421	23.6684374	460	24.277571	445	24.6701961	486	21.854522	444	0.966949149	-0.090844524	normal	0.950666963	0.185090302	normal	0.96929148	-0.059167621	normal	0.98465399	0.010769262	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02890|4.99116e-138|ggo:101153489|MRPL22; 39S ribosomal protein L22, mitochondrial isoform 1; K02890 large subunit ribosomal protein L22 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L22p/L17e	"39S ribosomal protein L22, mitochondrial (Precursor) GN=MRPL22 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L22, mitochondrial isoform X5 [Oryctolagus cuniculus]"
ENSG00000082516(GEMIN5)	--	11.6474	1325	10.9328	1238	12.8616	1447	11.67	1321	11.6851	1320	9.72841	1103	0.982302291	-0.035153332	normal	0.980187783	0.071016038	normal	0.731291174	-0.399443892	normal	0.580166073	-0.12046186	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K13133|0|hsa:25929|GEMIN5, GEMIN-5; gem (nuclear organelle) associated protein 5; K13133 gem associated protein 5 (A)"	RNA transport (ko03013)	--	--	"WD domain, G-beta repeat"	Gem-associated protein 5 GN=GEMIN5 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: gem-associated protein 5 isoform X2 [Pteropus alecto]
ENSG00000082556(OPRK1)	--	0	0	0.040054732	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04214|0|hsa:4986|OPRK1, K-OR-1, KOR, KOR-1, OPRK; opioid receptor, kappa 1; K04214 kappa-type opioid receptor (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Kappa-type opioid receptor GN=OPRK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kappa-type opioid receptor-like [Tupaia chinensis] 
ENSG00000082641(NFE2L1)	--	81.6781152	7345	77.99319905	6979	78.29667126	7198	75.58562104	6939	70.65546479	6316	83.73038459	7416	0.993574907	-0.112842697	normal	0.990560449	-0.165398024	normal	0.995015328	0.034746507	normal	0.753068962	-0.079219557	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09040|0|ptr:455185|NFE2L1; nuclear factor, erythroid 2-like 1; K09040 nuclear factor erythroid 2-related factor 1/3 (A)"	--	[K]	Transcription	bZIP Maf transcription factor;; bZIP transcription factor;; Basic region leucine zipper	Nuclear factor erythroid 2-related factor 1 GN=NFE2L1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear factor erythroid 2-related factor 1 isoform X1 [Galeopterus variegatus]
ENSG00000082684(SEMA5B)	--	0.116534821	6	0.074801725	2	0.147998212	4	0.028944789	2	0.126512055	8	0.036694297	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06841|0|hsa:54437|SEMA5B, SEMAG, SemG; sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B; K06841 semaphorin 5 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Thrombospondin type 1 domain;; Plexin repeat	Semaphorin-5B GN=SEMA5B OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: semaphorin-5B [Ceratotherium simum simum]
ENSG00000082701(GSK3B)	--	21.60838401	1634	22.4069065	1995	23.70748179	1786	22.95766721	1984	22.22425175	2073	28.1126353	2460	0.953825244	0.248959077	normal	0.98639358	0.033879618	normal	0.569566761	0.453306394	normal	0.203395376	0.246627103	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K03083|0|aml:100479224|GSK3B; glycogen synthase kinase 3 beta; K03083 glycogen synthase kinase 3 beta [EC:2.7.11.26] (A)	ErbB signaling pathway (ko04012);; Chemokine signaling pathway (ko04062);; Cell cycle (ko04110);; PI3K-Akt signaling pathway (ko04151);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Axon guidance (ko04360);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Neurotrophin signaling pathway (ko04722);; Dopaminergic synapse (ko04728);; Insulin signaling pathway (ko04910);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Basal cell carcinoma (ko05217)	[G]	Carbohydrate transport and metabolism	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Glycogen synthase kinase-3 beta GN=GSK3B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: glycogen synthase kinase-3 beta isoform X1 [Ailuropoda melanoleuca]
ENSG00000082781(ITGB5)	--	279.2830284	21640	264.1281958	21278	252.6076239	19856	112.7373558	8934	118.1056516	8946	125.0909336	9486	1.48E-13	-1.307005193	down	2.74E-12	-1.271330546	down	1.22E-08	-1.073873607	down	7.70E-16	-1.21893011	down	--	--	--	"K06588|0|pps:100979758|ITGB5; integrin, beta 5; K06588 integrin beta 5 (A)"	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Regulation of actin cytoskeleton (ko04810);; Proteoglycans in cancer (ko05205);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; Integrin beta cytoplasmic domain;; Integrin beta tail domain;; EGF-like domain"	Integrin beta-5 (Precursor) GN=ITGB5 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: integrin beta-5 [Oryctolagus cuniculus]
ENSG00000082805(ERC1)	--	9.97065629	2081	12.63369453	2236	12.8868047	2176	13.44310598	2416	13.2290157	2360	12.83042515	2009	0.976375706	0.1843848	normal	0.987013229	0.056402981	normal	0.982869278	-0.123403151	normal	0.876094069	0.041760983	normal	--	--	Cellular Component: presynaptic active zone (GO:0048786);; 	K16072|0|mcf:102123241|ERC1; ELKS/RAB6-interacting/CAST family member 1; K16072 ELKS/RAB6-interacting/CAST family member 1 (A)	NF-kappa B signaling pathway (ko04064)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RIM-binding protein of the cytomatrix active zone;; FIP domain	ELKS/Rab6-interacting/CAST family member 1 GN=ERC1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ELKS/Rab6-interacting/CAST family member 1 isoform 1 [Ceratotherium simum simum]
ENSG00000082898(XPO1)	--	116.283127	8238	124.749888	8810	127.788467	9036	104.3582849	7583	88.83989192	6433	97.5428671	6898	0.99272384	-0.150328431	normal	0.671744258	-0.474981044	normal	0.88622402	-0.397721159	normal	0.047875967	-0.340147025	normal	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	K14290|0|mcf:101925881|hypothetical protein; K14290 exportin-1 (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	CRM1 C terminal;; Exportin 1-like protein;; Importin-beta N-terminal domain	Exportin-1 GN=XPO1 OS=Homo sapiens (Human) PE=1 SV=1	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	exportin-1 [Bos taurus] 
ENSG00000082996(RNF13)	--	27.08860406	1007	31.483315	1160	28.38055108	1054	30.36971573	1119	31.94003007	1153	38.18134463	1399	0.974222985	0.121138708	normal	0.980467938	-0.030119465	normal	0.728719319	0.399730241	normal	0.413190083	0.168056711	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metal ion binding (GO:0046872);; 	K15692|0|hgl:101725061|Rnf13; ring finger protein 13; K15692 E3 ubiquitin-protein ligase RNF13 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; PA domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF13 (Precursor) GN=RNF13 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF13 isoform X1 [Pteropus alecto] 
ENSG00000083067(TRPM3)	--	0	0	0.019517369	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein tetramerization (GO:0051262);; Biological Process: transmembrane transport (GO:0055085);; 	K04978|0|aml:100484739|transient receptor potential cation channel subfamily M member 3-like; K04978 transient receptor potential cation channel subfamily M member 3 (A)	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein	Transient receptor potential cation channel subfamily M member 3 GN=TRPM3 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily M member 3 isoform X6 [Felis catus] 
ENSG00000083093(PALB2)	--	7.000242222	530	6.99841695	553	7.258510226	567	7.9533976	565	6.737391774	533	8.035157599	640	0.970983999	0.061254252	normal	0.969434353	-0.074363346	normal	0.95914941	0.166014726	normal	0.868332882	0.054187507	normal	--	--	--	"K10897|0|hsa:79728|PALB2, FANCN, PNCA3; partner and localizer of BRCA2; K10897 partner and localizer of BRCA2 (A)"	Fanconi anemia pathway (ko03460)	--	--	--	Partner and localizer of BRCA2 GN=PALB2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: partner and localizer of BRCA2 [Ceratotherium simum simum]
ENSG00000083097(DOPEY1)	--	1.388989203	215	2.335057191	248	1.230516752	190	1.989664118	259	1.724254381	269	1.930972107	314	0.936448108	0.236243327	normal	0.962269087	0.095281527	normal	0.05139131	0.712020395	normal	0.214978978	0.345747319	normal	[K]	Transcription	--	--	--	[K]	Transcription	"Dopey, N-terminal"	Protein dopey-1 GN=DOPEY1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: protein dopey-1 [Tupaia chinensis]
ENSG00000083099(LYRM2)	--	12.493128	735	12.3209211	758	12.72874	689	10.07281	704	12.220306	721	15.49044	814	0.971911195	-0.092802837	normal	0.971684157	-0.093433985	normal	0.941597413	0.231764852	normal	0.967377887	0.016295691	normal	--	--	--	--	--	--	--	Complex 1 protein (LYR family);; Complex1_LYR-like	LYR motif-containing protein 2 GN=LYRM2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LYR motif-containing protein 2 [Eptesicus fuscus]
ENSG00000083123(BCKDHB)	--	12.00897259	389	11.52818506	329	10.14407001	320	9.68927	312	8.723113	267	9.365493	298	0.84604029	-0.347520078	normal	0.881606802	-0.321032998	normal	0.962417102	-0.110509694	normal	0.328786743	-0.26471862	normal	[C]	Energy production and conversion	--	"K00167|0|ptr:462845|BCKDHB; branched chain keto acid dehydrogenase E1, beta polypeptide; K00167 2-oxoisovalerate dehydrogenase E1 component beta subunit [EC:1.2.4.4] (A)"	"Valine, leucine and isoleucine degradation (ko00280)"	[C]	Energy production and conversion	"Transketolase, pyrimidine binding domain;; Transketolase, C-terminal domain"	"2-oxoisovalerate dehydrogenase subunit beta, mitochondrial (Precursor) GN=BCKDHB OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial [Oryctolagus cuniculus]"
ENSG00000083168(KAT6A)	--	8.23952651	1630	9.0069614	1720	8.646341754	1710	11.2230644	1817	9.530835585	1828	10.05007621	1998	0.980255686	0.1257419	normal	0.984111555	0.066374336	normal	0.96598866	0.216091853	normal	0.508894623	0.136439291	normal	[B]	Chromatin structure and dynamics	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	"K11305|0|hsa:7994|KAT6A, MOZ, MYST3, RUNXBP2, ZC2HC6A, ZNF220; K(lysine) acetyltransferase 6A (EC:2.3.1.48); K11305 histone acetyltransferase MYST3 [EC:2.3.1.48] (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[B]	Chromatin structure and dynamics	MOZ/SAS family;; PHD-finger	Histone acetyltransferase KAT6A GN=KAT6A OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase KAT6A [Mustela putorius furo]
ENSG00000083223(ZCCHC6)	--	6.514300258	911	6.541643552	926	8.337735687	1097	6.803847	847	7.183163408	908	7.92386045	962	0.969690907	-0.135683943	normal	0.977107012	-0.049664543	normal	0.959719948	-0.197455265	normal	0.555175939	-0.131325569	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K13291|0|hsa:79670|ZCCHC6, PAPD6, TUT7; zinc finger, CCHC domain containing 6 (EC:2.7.7.52); K13291 terminal uridylyltransferase [EC:2.7.7.52] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cid1 family poly A polymerase;; Zinc knuckle;; Zinc knuckle;; Nucleotidyltransferase domain	Terminal uridylyltransferase 7 GN=ZCCHC6 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: terminal uridylyltransferase 7 isoformX1 [Equus caballus]
ENSG00000083290(ULK2)	--	11.9698	1106	11.50234	1018	10.34616	919	9.775395	896	10.052805	928	10.76774001	1014	0.860878071	-0.334096224	normal	0.967856951	-0.154726558	normal	0.97146609	0.133420354	normal	0.590310728	-0.121671502	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08269|0|hsa:9706|ULK2, ATG1B, Unc51.2; unc-51 like autophagy activating kinase 2 (EC:2.7.11.1); K08269 serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1] (A)"	Regulation of autophagy (ko04140);; mTOR signaling pathway (ko04150)	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Protein kinase domain;; Domain of unknown function (DUF3543);; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family	Serine/threonine-protein kinase ULK2 GN=ULK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase ULK2 isoform X3 [Canis lupus familiaris]
ENSG00000083307(GRHL2)	--	0	0	0	0	0	0	0.020676462	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K09275|0|pps:100972389|GRHL2; grainyhead-like 2 (Drosophila); K09275 transcription factor CP2 and related proteins (A)	--	[K]	Transcription	CP2 transcription factor	Grainyhead-like protein 2 homolog GN=GRHL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: grainyhead-like protein 2 homolog [Equus caballus] 
ENSG00000083312(TNPO1)	--	70.46809	6095	78.11068	7110	75.64058	6416	81.10714849	7793	77.44172356	7133	71.21754069	6720	0.955941563	0.323648031	normal	0.994839945	-0.016763584	normal	0.994307617	0.058482179	normal	0.595411495	0.119970726	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	K18752|0|ptr:461817|TNPO1; transportin 1; K18752 transportin-1 (A)	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	HEAT repeat;; HEAT-like repeat;; HEAT repeats;; Vacuolar 14 Fab1-binding region;; Armadillo/beta-catenin-like repeat;; non-SMC mitotic condensation complex subunit 1;; Importin-beta N-terminal domain;; Adaptin N terminal region;; Myosin-binding striated muscle assembly central	Transportin-1 GN=TNPO1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transportin-1 isoform 1 [Ovis aries] 
ENSG00000083444(PLOD1)	--	52.1884433	3204	49.08433501	3044	50.24646623	3098	56.71515671	3341	50.49213729	3028	44.67664033	2743	0.990694511	0.02955969	normal	0.989868172	-0.029015258	normal	0.980341345	-0.18377856	normal	0.82079142	-0.058374018	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00473|0|hsa:5351|PLOD1, EDS6, LH, LH1, LLH, PLOD; procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 (EC:1.14.11.4); K00473 procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [EC:1.14.11.4] (A)"	Lysine degradation (ko00310)	[O]	"Posttranslational modification, protein turnover, chaperones"	2OG-Fe(II) oxygenase superfamily	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (Precursor) GN=PLOD1 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 [Tupaia chinensis] "
ENSG00000083454(P2RX5)	--	7.8042841	314	7.385825721	303	7.470382396	309	6.464953	252	6.0337995	239	6.91105756	273	0.858840156	-0.346277244	normal	0.844062864	-0.361695832	normal	0.949628223	-0.186028044	normal	0.273071578	-0.298407726	normal	--	--	Molecular Function: purinergic nucleotide receptor activity (GO:0001614);; Molecular Function: extracellular ATP-gated cation channel activity (GO:0004931);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: response to ATP (GO:0033198);; Biological Process: cation transmembrane transport (GO:0098655);; 	"K05219|0|hsa:5026|P2RX5, LRH-1, P2X5, P2X5R; purinergic receptor P2X, ligand-gated ion channel, 5; K05219 P2X purinoceptor 5 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	--	--	ATP P2X receptor	P2X purinoceptor 5 GN=P2RX5 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: P2X purinoceptor 5 [Galeopterus variegatus]
ENSG00000083457(ITGAE)	--	2.720366	210	2.393573	185	2.28128	177	3.891125	300	3.485461	266	2.993644	230	0.614288051	0.480784328	normal	0.602241283	0.499055345	normal	0.861847707	0.366836142	normal	0.092722787	0.454599375	normal	--	--	--	"K06524|0|hsa:3682|ITGAE, CD103, HUMINAE; integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide); K06524 integrin alpha E (A)"	Regulation of actin cytoskeleton (ko04810)	[W]	Extracellular structures	"Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; von Willebrand factor type A domain;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella;; Integrin alpha cytoplasmic region"	Integrin alpha-E heavy chain (Precursor) GN=ITGAE OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: integrin alpha-E [Ceratotherium simum simum]
ENSG00000083520(DIS3)	--	10.5973	1037	9.08668	890	10.09899	954	12.10789	1186	12.19677	1204	11.50528	1124	0.968854221	0.162630427	normal	0.691191073	0.413924822	normal	0.949588515	0.227956166	normal	0.136419042	0.265233467	normal	[K]	Transcription	--	K12585|0|pps:100991012|DIS3; DIS3 exosome endoribonuclease and 3'-5' exoribonuclease; K12585 exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-] (A)	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	RNB domain;; PIN domain	Exosome complex exonuclease RRP44 GN=DIS3 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex exonuclease RRP44 isoformX1 [Equus caballus] 
ENSG00000083535(PIBF1)	--	3.170176	201	3.32340452	210	3.37664808	211	3.397593631	221	2.893785	186	3.371698	217	0.962553303	0.105251188	normal	0.948589367	-0.195019897	normal	0.966603398	0.031934899	normal	0.981574081	-0.016652485	normal	--	--	--	"K16538|0|hsa:10464|PIBF1, C13orf24, CEP90, PIBF; progesterone immunomodulatory binding factor 1; K16538 progesterone-induced-blocking factor 1 (A)"	--	--	--	--	Progesterone-induced-blocking factor 1 GN=PIBF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: progesterone-induced-blocking factor 1 [Oryctolagus cuniculus] 
ENSG00000083544(TDRD3)	--	3.677191706	202	2.855476343	157	3.023527025	166	3.666225168	206	3.633442758	202	3.753845495	207	0.966988839	-0.002524208	normal	0.892755941	0.339276479	normal	0.911736102	0.307641529	normal	0.581825633	0.207004316	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: mRNA processing (GO:0006397);; 	K18404|0|hsa:81550|TDRD3; tudor domain containing 3; K18404 tudor domain-containing protein 3 (A)	--	[S]	Function unknown	Domain of unknown function (DUF1767);; Tudor domain;; Survival motor neuron protein (SMN);; UBA/TS-N domain	Tudor domain-containing protein 3 GN=TDRD3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: tudor domain-containing protein 3-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000083635(NUFIP1)	--	4.6092	275	4.81023	283	4.924242	282	4.0617	243	4.093950001	244	3.16947	189	0.944263788	-0.208069861	normal	0.934748209	-0.233999352	normal	0.322916541	-0.58176363	normal	0.230419128	-0.335208026	normal	--	--	--	--	--	--	--	Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1);; Zinc-finger double-stranded RNA-binding	Nuclear fragile X mental retardation-interacting protein 1 GN=NUFIP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear fragile X mental retardation-interacting protein 1 [Ceratotherium simum simum]
ENSG00000083642(PDS5B)	--	6.935283422	822	7.8691763	841	8.034945312	902	7.110084	767	7.8284176	833	5.909707	696	0.968995081	-0.1304915	normal	0.976480395	-0.035152349	normal	0.765558371	-0.381601104	normal	0.393339222	-0.181095317	normal	--	--	--	"K11267|0|hsa:23047|PDS5B, APRIN, AS3, CG008; PDS5 cohesin associated factor B; K11267 sister chromatid cohesion protein PDS5 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: sister chromatid cohesion protein PDS5 homolog B isoform X5 [Canis lupus familiaris]
ENSG00000083720(OXCT1)	--	1.09234165	54	2.1123546	94	1.831707958	88	3.331008607	147	2.825278505	114	1.946885241	95	3.47E-05	1.389063392	up	0.949845719	0.253171394	normal	0.969595592	0.100470453	normal	0.152373616	0.57074865	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: CoA-transferase activity (GO:0008410);; 	"K01027|0|hsa:5019|OXCT1, OXCT, SCOT; 3-oxoacid CoA transferase 1 (EC:2.8.3.5); K01027 3-oxoacid CoA-transferase [EC:2.8.3.5] (A)"	"Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Butanoate metabolism (ko00650)"	[C]	Energy production and conversion	Coenzyme A transferase	"Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (Precursor) GN=OXCT1 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial [Oryctolagus cuniculus]"
ENSG00000083750(RRAGB)	--	6.3125408	198	7.762808393	275	6.681038864	231	10.107456	315	8.286431759	282	11.05725387	364	0.156866527	0.635080518	normal	0.966402881	0.01475685	normal	0.106526328	0.644365619	normal	0.085332831	0.428043628	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K16185|0|mcc:704260|RRAGB; Ras-related GTP binding B; K16185 Ras-related GTP-binding protein A/B (A)	mTOR signaling pathway (ko04150)	[T]	Signal transduction mechanisms	Gtr1/RagA G protein conserved region;; Ras family;; ADP-ribosylation factor family	Ras-related GTP-binding protein B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related GTP-binding protein B-like isoform X1 [Camelus ferus] 
ENSG00000083799(CYLD)	--	6.119207277	447	5.803824575	496	6.056561756	498	9.796616454	773	5.922344331	626	8.356700734	661	0.003005351	0.757358989	normal	0.879469255	0.313543375	normal	0.726267956	0.399157617	normal	0.005770946	0.493902312	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K08601|0|pon:100171734|CYLD, CYLD1; cylindromatosis (turban tumor syndrome) (EC:3.4.19.12); K08601 ubiquitin thioesterase CYLD [EC:3.4.19.12] (A)"	Osteoclast differentiation (ko04380);; RIG-I-like receptor signaling pathway (ko04622)	[R]	General function prediction only	CAP-Gly domain;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase CYLD GN=CYLD OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase CYLD isoform 1 [Orcinus orca]
ENSG00000083807(SLC27A5)	--	26.76794899	196	22.48192996	175	27.92728116	214	20.45910583	163	20.90109961	154	23.4998988	180	0.920012845	-0.294280029	normal	0.949130813	-0.20397063	normal	0.933022718	-0.255930722	normal	0.484725212	-0.255830205	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K08748|0|hsa:10998|SLC27A5, ACSB, ACSVL6, BACS, BAL, FACVL3, FATP-5, FATP5, VLACSR, VLCS-H2, VLCSH2; solute carrier family 27 (fatty acid transporter), member 5 (EC:6.2.1.7); K08748 solute carrier family 27 (fatty acid transporter), member 5 [EC:6.2.1.7] (A)"	Primary bile acid biosynthesis (ko00120);; PPAR signaling pathway (ko03320);; Bile secretion (ko04976)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	Bile acyl-CoA synthetase GN=SLC27A5 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: bile acyl-CoA synthetase [Panthera tigris altaica]
ENSG00000083812(ZNF324)	--	10.00135948	616	9.242045051	591	8.884750803	568	9.447843316	544	10.90992667	630	11.20149954	657	0.946272546	-0.209599183	normal	0.97103476	0.070592172	normal	0.950015126	0.201212478	normal	0.9508736	0.024119343	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:25799|ZNF324, ZF5128, ZNF324A; zinc finger protein 324; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 324A GN=ZNF324 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 324A-like [Galeopterus variegatus]
ENSG00000083814(ZNF671)	--	1.205985	48	1.208310012	53	1.148393	45	1.1762763	58	1.646876	67	1.514672	71	0.971678442	0.235326313	normal	0.959199674	0.30888841	normal	0.835221965	0.632543395	normal	0.485739364	0.404103815	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:79891|ZNF671; zinc finger protein 671; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc-finger domain;; DNA directed RNA polymerase, 7 kDa subunit"	Zinc finger protein 671 GN=ZNF671 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 671-like [Equus caballus]
ENSG00000083817(ZNF416)	--	2.456103	118	2.317047719	113	2.291157202	110	2.669878501	129	2.76291664	133	3.17992859	154	0.966599443	0.09654941	normal	0.953146854	0.211070919	normal	0.800672211	0.47163098	normal	0.542842435	0.266070135	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:55659|ZNF416; zinc finger protein 416; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; DNA directed RNA polymerase, 7 kDa subunit"	Zinc finger protein 416 GN=ZNF416 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 416-like [Galeopterus variegatus]
ENSG00000083828(ZNF586)	--	17.59704882	1495	17.01680634	1490	16.11760482	1479	16.00724978	1505	17.89660175	1593	17.09741069	1602	0.98390923	-0.021192554	normal	0.982181636	0.074933817	normal	0.980546761	0.106855647	normal	0.837914133	0.053325347	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; XPA protein N-terminal;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 586 GN=ZNF586 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 154-like [Bubalus bubalis]
ENSG00000083844(ZNF264)	--	7.989433062	410	8.297110344	367	8.031386732	348	6.78702655	400	7.918540649	342	8.564474766	372	0.967806382	-0.066204979	normal	0.960655486	-0.122686449	normal	0.965471974	0.087555809	normal	0.931264308	-0.03581894	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:9422|ZNF264; zinc finger protein 264; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Transposase zinc-ribbon domain"	Zinc finger protein 264 GN=ZNF264 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 264 [Galeopterus variegatus]
ENSG00000083845(RPS5)	--	1404.265478	14231	1203.705749	12482	1251.910272	13163	1422.517694	15058	1490.353227	15065	1365.563427	14204	0.997141713	0.050655542	normal	0.989191231	0.249897405	normal	0.996393036	0.101506261	normal	0.5827018	0.13132003	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02989|1.56069e-145|umr:103677222|RPS5; ribosomal protein S5; K02989 small subunit ribosomal protein S5e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S7p/S5e	"40S ribosomal protein S5, N-terminally processed GN=RPS5 OS=Homo sapiens (Human) PE=1 SV=4"	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S5-like [Chrysochloris asiatica]
ENSG00000083857(FAT1)	--	32.32722421	8855	37.17399711	9683	37.42316408	9148	39.43085694	10040	44.1172324	11219	38.82504894	10341	0.993694623	0.150338286	normal	0.992062698	0.190963803	normal	0.993000276	0.168529773	normal	0.429619118	0.169676968	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16506|0|hsa:2195|FAT1, CDHF7, CDHR8, FAT, ME5, hFat1; FAT atypical cadherin 1; K16506 protocadherin Fat 1/2/3 (A)"	--	[T]	Signal transduction mechanisms	Cadherin domain;; Laminin G domain;; Laminin G domain;; EGF-like domain;; Cadherin-like;; Concanavalin A-like lectin/glucanases superfamily;; Calcium-binding EGF domain	"Protocadherin Fat 1, nuclear form (Precursor) GN=FAT1 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: protocadherin Fat 1 [Galeopterus variegatus] 
ENSG00000083896(YTHDC1)	--	17.99008968	1277	18.6364033	1387	19.33326298	1432	18.47161182	1396	16.61483426	1200	21.67712787	1575	0.979445773	0.097595828	normal	0.953666636	-0.230089947	normal	0.978204226	0.128899052	normal	0.989637954	0.005398355	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	--	--	[TA]	Signal transduction mechanisms;; RNA processing and modification	YT521-B-like domain	YTH domain-containing protein 1 GN=YTHDC1 OS=Homo sapiens (Human) PE=1 SV=3	AT	RNA processing and modification;; Signal transduction mechanisms	PREDICTED: YTH domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000083937(CHMP2B)	--	39.23448305	1528	45.70749038	1767	45.42373001	1735	55.64639699	2183	53.66069992	2067	53.3892002	2030	0.419782534	0.483426746	normal	0.969501225	0.20464772	normal	0.965737979	0.218076726	normal	0.066704586	0.298852332	normal	--	--	Biological Process: vacuolar transport (GO:0007034);; 	K12192|3.36438e-113|pps:100972013|CHMP2B; charged multivesicular body protein 2B; K12192 charged multivesicular body protein 2B (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snf7	Charged multivesicular body protein 2b GN=CHMP2B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	charged multivesicular body protein 2b [Sus scrofa]
ENSG00000084070(SMAP2)	--	5.279670536	299	4.255592939	242	5.340994201	302	6.334485167	343	4.985377477	271	4.373101181	238	0.953865648	0.16643192	normal	0.957014112	0.141026134	normal	0.858219534	-0.349899861	normal	0.995821807	-0.006784886	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; 	"K12486|0|ptr:456793|SMAP2, SMAP1L; small ArfGAP2; K12486 stromal membrane-associated protein (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf	Stromal membrane-associated protein 2 GN=SMAP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: stromal membrane-associated protein 2 isoform X1 [Tupaia chinensis]
ENSG00000084072(PPIE)	--	19.24844747	435	20.43707434	466	19.27322784	447	15.65032123	361	17.32983635	389	17.81603007	406	0.894029876	-0.29868872	normal	0.907450689	-0.280986755	normal	0.959309375	-0.146566028	normal	0.323841663	-0.242528199	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K09564|0|hsa:10450|PPIE, CYP-33, CYP33; peptidylprolyl isomerase E (cyclophilin E) (EC:5.2.1.8); K09564 peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8] (A)"	Spliceosome (ko03040)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Peptidyl-prolyl cis-trans isomerase E GN=PPIE OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase E isoform X1 [Mustela putorius furo] 
ENSG00000084073(ZMPSTE24)	--	33.8941	1423	34.0425	1436	35.2713	1459	37.8626	1614	36.7228	1537	33.7644	1420	0.975616198	0.150719786	normal	0.9816807	0.076556921	normal	0.982941602	-0.047330665	normal	0.811240342	0.06061423	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K06013|0|hsa:10269|ZMPSTE24, FACE-1, FACE1, HGPS, PRO1, STE24, Ste24p; zinc metallopeptidase STE24 (EC:3.4.24.84); K06013 STE24 endopeptidase [EC:3.4.24.84] (A)"	Terpenoid backbone biosynthesis (ko00900)	[R]	General function prediction only	Peptidase family M48	CAAX prenyl protease 1 homolog GN=ZMPSTE24 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	zinc metallopeptidase STE24 [Equus caballus] 
ENSG00000084090(STARD7)	--	56.66206001	2968	58.06432	3085	58.6011	3073	49.77437671	2630	49.57605	2585	41.05679069	2145	0.976123043	-0.205147648	normal	0.954366013	-0.276384534	normal	0.254898602	-0.526649623	normal	0.036853403	-0.332006265	normal	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[I]	Lipid transport and metabolism	START domain	"StAR-related lipid transfer protein 7, mitochondrial (Precursor) GN=STARD7 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: stAR-related lipid transfer protein 7, mitochondrial, partial [Equus caballus]"
ENSG00000084092(NOA1)	--	12.4605	700	12.4481	705	12.6073	719	11.0528	624	11.327	638	11.0313	625	0.952469338	-0.196184741	normal	0.96019229	-0.165120865	normal	0.948414509	-0.209952963	normal	0.385517432	-0.191818147	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	50S ribosome-binding GTPase	Nitric oxide-associated protein 1 GN=NOA1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: nitric oxide-associated protein 1 [Galeopterus variegatus]
ENSG00000084093(REST)	--	7.3663022	860	8.7351375	1009	7.078066196	898	7.988281149	985	8.122345552	926	8.365993537	1026	0.965466743	0.164679752	normal	0.969338233	-0.145041622	normal	0.962122286	0.183662381	normal	0.809168413	0.064818874	normal	[R]	General function prediction only	--	"K09222|0|hsa:5978|REST, NRSF, XBR; RE1-silencing transcription factor; K09222 RE1-silencing transcription factor (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550);; Huntington's disease (ko05016)	[R]	General function prediction only	"Zinc-finger double domain;; C2H2-type zinc-finger domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	RE1-silencing transcription factor GN=REST OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: RE1-silencing transcription factor [Galeopterus variegatus]
ENSG00000084110(HAL)	--	0.042596729	3	0.053150033	2	0.056992662	3	0.136140167	3	0.280779467	6	0.042531919	3	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	--	K01745|0|ptr:452144|HAL; histidine ammonia-lyase; K01745 histidine ammonia-lyase [EC:4.3.1.3] (A)	Histidine metabolism (ko00340)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Aromatic amino acid lyase	Histidine ammonia-lyase GN=HAL OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: histidine ammonia-lyase isoform X1 [Tupaia chinensis] 
ENSG00000084112(SSH1)	--	11.10619482	2512	9.82956736	2409	11.27340125	2623	10.48508507	2453	10.91432571	2401	10.55772424	2438	0.987773336	-0.06508121	normal	0.98802207	-0.026209067	normal	0.985651116	-0.113743085	normal	0.771874041	-0.070103403	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K05766|0|cjc:100414066|SSH1; slingshot protein phosphatase 1; K05766 protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48] (A)	Regulation of actin cytoskeleton (ko04810)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; DEK C terminal domain"	Protein phosphatase Slingshot homolog 1 GN=SSH1 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: protein phosphatase Slingshot homolog 1 [Ceratotherium simum simum]
ENSG00000084207(GSTP1)	--	469.483249	6818	492.076428	7533	453.419526	7036	569.4855	8548	606.060439	8792	527.343251	7891	0.971377166	0.295346502	normal	0.989485096	0.201502825	normal	0.991974731	0.157129309	normal	0.262359906	0.217017795	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K00799|8.30179e-153|hsa:2950|GSTP1, DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI; glutathione S-transferase pi 1 (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Pathways in cancer (ko05200);; Chemical carcinogenesis (ko05204);; Prostate cancer (ko05215)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain"	Glutathione S-transferase P GN=GSTP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase P-like [Equus caballus]
ENSG00000084234(APLP2)	--	96.55660631	7364	87.00014836	6804	88.92529203	6847	103.4847736	7935	103.9632621	7882	102.1206394	7836	0.994731059	0.076892876	normal	0.989511347	0.19071264	normal	0.989970421	0.18631545	normal	0.491761324	0.149336796	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Molecular Function: heparin binding (GO:0008201);; Molecular Function: transition metal ion binding (GO:0046914);; 	K08117|0|pon:100449545|APLP2; amyloid beta (A4) precursor-like protein 2; K08117 amyloid beta (A4) precursor-like protein 2 (A)	--	[R]	General function prediction only	"E2 domain of amyloid precursor protein;; Amyloid A4 N-terminal heparin-binding;; beta-amyloid precursor protein C-terminus;; Copper-binding of amyloid precursor, CuBD;; Kunitz/Bovine pancreatic trypsin inhibitor domain"	Amyloid-like protein 2 (Precursor) GN=APLP2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: amyloid-like protein 2 isoform X1 [Mustela putorius furo] 
ENSG00000084444(FAM234B)	--	3.619160462	288	3.038747628	241	3.63405	287	4.311118	344	3.866238217	306	4.018346501	319	0.937928797	0.22441099	normal	0.884713062	0.321279142	normal	0.95797773	0.143496752	normal	0.433004217	0.226651447	normal	--	--	--	--	--	--	--	--	Uncharacterized protein KIAA1467 GN=KIAA1467 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA1467 homolog [Pteropus alecto]
ENSG00000084453(SLCO1A2)	--	0.017136365	2	0.008516226	1	0.017130528	1	0.067818042	8	0.024981626	2	0.034021672	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K03460|0|hsa:6579|SLCO1A2, OATP, OATP-A, OATP1A2, SLC21A3; solute carrier organic anion transporter family, member 1A2; K03460 solute carrier organic anion transporter family, member 1A (A)"	Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain	Solute carrier organic anion transporter family member 1A2 GN=SLCO1A2 OS=Homo sapiens (Human) PE=2 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 1A2 isoformX2 [Canis lupus familiaris] 
ENSG00000084463(WBP11)	--	22.09391113	1863	23.74880627	1980	23.97770557	1985	26.25220546	2204	26.084827	2183	23.561407	1988	0.968958759	0.211503778	normal	0.9828142	0.119298342	normal	0.986817081	-0.006108043	normal	0.62012606	0.107995515	normal	--	--	Biological Process: RNA processing (GO:0006396);; 	"K12866|0|hsa:51729|WBP11, NPWBP, PPP1R165, SIPP1, WBP-11; WW domain binding protein 11; K12866 WW domain-binding protein 11 (A)"	Spliceosome (ko03040)	[S]	Function unknown	WW domain binding protein 11	WW domain-binding protein 11 GN=WBP11 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: WW domain-binding protein 11 [Orcinus orca] 
ENSG00000084623(EIF3I)	--	112.1929703	2948	110.3488466	2873	109.8461878	2899	128.4448071	3410	128.6041473	3345	117.7123524	3115	0.982099631	0.1791161	normal	0.978925338	0.197925033	normal	0.988273175	0.095337401	normal	0.423320215	0.157274197	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03246|0|pps:100976979|EIF3I; eukaryotic translation initiation factor 3, subunit I; K03246 translation initiation factor 3 subunit I (A)"	RNA transport (ko03013)	[JT]	"Translation, ribosomal structure and biogenesis;; Signal transduction mechanisms"	"WD domain, G-beta repeat"	Eukaryotic translation initiation factor 3 subunit I {ECO:0000255|HAMAP-Rule:MF_03008} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit I [Ochotona princeps]
ENSG00000084628(NKAIN1)	--	0.8529341	26	0.6748443	23	0.40723261	21	1.392918523	35	0.574253309	28	0.915901893	39	0.976209523	0.378669777	normal	0.98304497	0.247594001	normal	0.875289079	0.839788684	normal	0.469652373	0.521944032	normal	--	--	--	--	--	[S]	Function unknown	"Na,K-Atpase Interacting protein"	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 (Precursor) GN=NKAIN1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1 [Orcinus orca] 
ENSG00000084636(COL16A1)	--	2.384734133	160	2.092611	167	2.920716171	210	2.752827705	166	2.707278881	196	3.93888417	265	0.967371616	0.022071001	normal	0.946881936	0.207840225	normal	0.888612589	0.325222295	normal	0.65811156	0.204215788	normal	--	--	--	--	--	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	Collagen alpha-1(XVI) chain (Precursor) GN=COL16A1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(XVI) chain isoform X2 [Felis catus]
ENSG00000084652(TXLNA)	--	16.29731821	1661	18.11099	1883	17.71869	1830	18.760805	1913	17.55796966	1766	19.47499	1981	0.974723515	0.172803507	normal	0.981691451	-0.113879752	normal	0.983117427	0.106009571	normal	0.834721539	0.053715476	normal	--	--	Molecular Function: syntaxin binding (GO:0019905);; 	--	--	[Z]	Cytoskeleton	Myosin-like coiled-coil protein	Alpha-taxilin GN=TXLNA OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: alpha-taxilin [Ceratotherium simum simum]
ENSG00000084676(NCOA1)	--	7.828296707	1160	7.934060674	1164	7.7482023	1119	5.47466227	782	6.205808358	871	5.579829917	840	0.06585512	-0.598743757	normal	0.602927439	-0.439110948	normal	0.651258861	-0.421380623	normal	0.001760596	-0.486786474	normal	--	--	"Molecular Function: transcription coactivator activity (GO:0003713);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: nuclear hormone receptor binding (GO:0035257);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09101|0|hsa:8648|NCOA1, F-SRC-1, KAT13A, RIP160, SRC1, bHLHe42, bHLHe74; nuclear receptor coactivator 1 (EC:2.3.1.48); K09101 nuclear receptor coactivator 1 [EC:2.3.1.48] (A)"	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	PAS domain;; Domain of unknown function (DUF1518);; Steroid receptor coactivator;; Nuclear receptor coactivator;; PAS fold;; PAS domain;; Helix-loop-helix DNA-binding domain	Nuclear receptor coactivator 1 GN=NCOA1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nuclear receptor coactivator 1 isoform X1 [Camelus dromedarius]
ENSG00000084693(AGBL5)	--	27.94986285	1215	24.106698	1028	24.49193129	1130	15.434617	709	16.17762441	728	16.35477451	721	0.000389916	-0.806578415	normal	0.289051809	-0.518345477	normal	0.020320123	-0.655435446	normal	9.34E-06	-0.665413618	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[E]	Amino acid transport and metabolism	Zinc carboxypeptidase	Cytosolic carboxypeptidase-like protein 5 GN=AGBL5 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cytosolic carboxypeptidase-like protein 5 [Trichechus manatus latirostris]
ENSG00000084710(EFR3B)	--	6.252510605	891	6.218589844	879	7.213759246	1040	9.948959153	1387	9.674565203	1368	7.048370863	1010	0.053457066	0.606793371	normal	0.052201408	0.615850839	normal	0.978956805	-0.050445239	normal	0.0767992	0.400343124	normal	--	--	--	--	--	[R]	General function prediction only	--	Protein EFR3 homolog B GN=EFR3B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein EFR3 homolog B isoform X1 [Camelus dromedarius]
ENSG00000084731(KIF3C)	--	25.25065435	2535	26.700294	2758	29.71471006	3067	28.18535596	2873	32.40708001	3243	31.87748839	3242	0.983454692	0.149654745	normal	0.975814325	0.212172627	normal	0.989551045	0.071730078	normal	0.488156383	0.142156987	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10394|0|hsa:3797|KIF3C; kinesin family member 3C; K10394 kinesin family member 3/17 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF3C GN=KIF3C OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF3C [Odobenus rosmarus divergens]
ENSG00000084733(RAB10)	--	163.2572	7291	192.5199	8749	181.4192	7769	128.8615	6213	126.9106	5496	152.0649	6801	0.978559712	-0.261599112	normal	0.011575432	-0.692010316	normal	0.988713956	-0.200231771	normal	0.019863554	-0.384272232	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07903|1.05762e-145|umr:103671673|RAB10; RAB10, member RAS oncogene family; K07903 Ras-related protein Rab-10 (A)"	AMPK signaling pathway (ko04152)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-10 GN=RAB10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Rab-10 [Orycteropus afer afer]
ENSG00000084734(GCKR)	--	0.0231692	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	--	--	--	Glucokinase regulatory protein GN=GCKR OS=Homo sapiens (Human) PE=1 SV=6	R	General function prediction only	PREDICTED: glucokinase regulatory protein isoform X1 [Ailuropoda melanoleuca]
ENSG00000084754(HADHA)	--	89.948035	5395	82.97631	4983	88.175886	5290	83.83592	4983	78.710259	4678	74.5681	4482	0.990120828	-0.145397547	normal	0.990996529	-0.11251402	normal	0.976359262	-0.247339604	normal	0.396302255	-0.169196767	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: fatty acid metabolic process (GO:0006631);; Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07515|0|hsa:3030|HADHA, ECHA, GBP, HADH, LCEH, LCHAD, MTPA, TP-ALPHA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit (EC:4.2.1.17 1.1.1.211); K07515 enoyl-CoA hydratase / long-chain 3-hydroxyacyl-CoA dehydrogenase [EC:4.2.1.17 1.1.1.211] (A)"	"Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; Biosynthesis of unsaturated fatty acids (ko01040);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	"Enoyl-CoA hydratase/isomerase family;; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain"	Long chain 3-hydroxyacyl-CoA dehydrogenase (Precursor) GN=HADHA OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	"PREDICTED: trifunctional enzyme subunit alpha, mitochondrial [Equus caballus] "
ENSG00000084764(MAPRE3)	--	16.29373012	543	12.75936658	426	15.05329726	506	12.97139915	433	16.11207438	534	12.61356881	423	0.820771869	-0.356285663	normal	0.889101862	0.303595383	normal	0.9177263	-0.265900758	normal	0.716359731	-0.106638517	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: protein binding (GO:0005515);; Molecular Function: microtubule binding (GO:0008017);; 	K07529|0|mcc:699648|DPYSL5; dihydropyrimidinase-like 5; K07529 dihydropyrimidinase-like 5 (A)	Axon guidance (ko04360)	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	EB1-like C-terminal motif;; Calponin homology (CH) domain	Microtubule-associated protein RP/EB family member 3 GN=MAPRE3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	Dihydropyrimidinase-related protein 5 [Pteropus alecto]
ENSG00000084774(CAD)	--	28.70187148	4109	29.85499403	4543	30.50450328	4545	21.42009243	3189	21.58216856	3088	22.389724	3280	0.822578929	-0.396346745	normal	0.131505591	-0.578164111	normal	0.524906782	-0.478687569	normal	0.001022032	-0.48663207	normal	[EF]	Amino acid transport and metabolism;; Nucleotide transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Biological Process: cellular amino acid metabolic process (GO:0006520);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; Molecular Function: amino acid binding (GO:0016597);; Molecular Function: carboxyl- or carbamoyltransferase activity (GO:0016743);; Molecular Function: hydrolase activity (GO:0016787);; 	"K11540|0|hsa:790|CAD; carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (EC:2.1.3.2 3.5.2.3 6.3.5.5); K11540 carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3] (A)"	"Pyrimidine metabolism (ko00240);; Alanine, aspartate and glutamate metabolism (ko00250)"	[R]	General function prediction only	"Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase small chain, CPSase domain;; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain;; Glutamine amidotransferase class-I;; Carbamoyl-phosphate synthetase large chain, oligomerisation domain;; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; ATP-grasp domain;; ATP-grasp domain;; MGS-like domain;; D-ala D-ala ligase C-terminus;; Amidohydrolase;; Amidohydrolase family;; Peptidase C26;; ATP-grasp domain;; Amidohydrolase"	Dihydroorotase GN=CAD OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: CAD protein [Leptonychotes weddellii]
ENSG00000085063(CD59)	--	144.3461486	3601	131.1402112	3432	149.7427313	3594	216.1205549	5319	184.4098668	4478	164.1521132	4078	0.284091717	0.531737446	normal	0.8977144	0.362238316	normal	0.98494922	0.173911184	normal	0.021898915	0.362774141	normal	--	--	--	"K04008|5.85685e-58|hsa:966|CD59, 16.3A5, 1F5, EJ16, EJ30, EL32, G344, HRF-20, HRF20, MAC-IP, MACIF, MEM43, MIC11, MIN1, MIN2, MIN3, MIRL, MSK21, p18-20; CD59 molecule, complement regulatory protein; K04008 CD59 antigen (A)"	Complement and coagulation cascades (ko04610);; Hematopoietic cell lineage (ko04640)	--	--	u-PAR/Ly-6 domain	CD59 glycoprotein (Precursor) GN=CD59 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CD59 glycoprotein [Orcinus orca]
ENSG00000085117(CD82)	--	5.474719285	137	2.755037418	114	3.578488251	149	9.471964885	265	8.47637117	268	5.380717202	184	0.002857066	0.913494661	normal	9.31E-06	1.201078522	up	0.923492399	0.293417484	normal	0.002402569	0.820194938	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06509|4.7387e-157|pps:100976050|CD82; CD82 molecule; K06509 CD82 antigen (A)	p53 signaling pathway (ko04115)	[R]	General function prediction only	Tetraspanin family	CD82 antigen GN=CD82 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CD82 antigen isoform X1 [Ochotona princeps]
ENSG00000085185(BCORL1)	--	7.09794534	1139	5.512602576	895	7.144862579	1117	5.65703424	870	5.408122884	880	3.087119592	500	0.658594637	-0.418863954	normal	0.976854436	-0.045732784	normal	3.75E-09	-1.165497486	down	0.110973261	-0.508228812	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	BCL-6 corepressor-like protein 1 GN=BCORL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: BCL-6 corepressor-like protein 1 [Odobenus rosmarus divergens]
ENSG00000085224(ATRX)	--	26.86669376	3526	38.95819018	4280	34.14835795	4064	33.1731678	4037	31.76092115	4110	26.5100878	3978	0.985777088	0.164351885	normal	0.991147505	-0.079870159	normal	0.991932931	-0.039133849	normal	0.979218376	0.009481085	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K10779|0|hsa:546|ATRX, ATR2, JMS, MRXHF1, RAD54, RAD54L, SFM1, SHS, XH2, XNP, ZNF-HX; alpha thalassemia/mental retardation syndrome X-linked (EC:3.6.4.12); K10779 transcriptional regulator ATRX [EC:3.6.4.12] (A)"	--	[K]	Transcription	SNF2 family N-terminal domain;; Helicase conserved C-terminal domain	Transcriptional regulator ATRX GN=ATRX OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: transcriptional regulator ATRX isoform 1 [Orcinus orca]
ENSG00000085231(AK6)	--	84.613492	1610	87.825039	1631	94.69607	1702	83.083693	1600	80.366457	1489	97.4765226	1794	0.984274141	-0.039782963	normal	0.975496837	-0.152691346	normal	0.984285594	0.067598902	normal	0.88850861	-0.038417296	normal	[F]	Nucleotide transport and metabolism	Molecular Function: ATP binding (GO:0005524);; 	K18532|7.03388e-124|pps:100989284|AK6; adenylate kinase 6; K18532 adenylate kinase [EC:2.7.4.3] (A)	Purine metabolism (ko00230);; Ribosome biogenesis in eukaryotes (ko03008)	[F]	Nucleotide transport and metabolism	AAA domain;; AAA domain;; Shikimate kinase;; ATPase family associated with various cellular activities (AAA);; Adenylate kinase	Adenylate kinase isoenzyme 6 {ECO:0000255|HAMAP-Rule:MF_03173} OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: adenylate kinase isoenzyme 6-like isoform X1 [Panthera tigris altaica] 
ENSG00000085274(MYNN)	--	5.644911021	345	4.528204387	315	5.325526367	319	5.888791409	366	5.794244558	370	6.729084962	433	0.967493954	0.05418075	normal	0.941942545	0.209816656	normal	0.678326897	0.430759855	normal	0.37678598	0.235156179	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; BTB/POZ domain;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Myoneurin GN=MYNN OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myoneurin isoform X1 [Leptonychotes weddellii]
ENSG00000085276(MECOM)	--	0.096673473	8	0.138469752	7	0.194414836	18	0.374507486	36	1.362763918	53	0.8321947	56	0.030297175	1.949049058	normal	5.35E-06	2.659737453	up	0.015246788	1.551626159	normal	6.17E-05	2.1173946	up	[R]	General function prediction only	--	"K04462|0|mcc:698603|MECOM, EVI1; MDS1 and EVI1 complex locus; K04462 ecotropic virus integration site 1 protein (A)"	MAPK signaling pathway (ko04010);; Pathways in cancer (ko05200);; Chronic myeloid leukemia (ko05220)	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; BED zinc finger"	Runt-related transcription factor 1 GN=RUNX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: MDS1 and EVI1 complex locus protein EVI1 isoform X1 [Condylura cristata]
ENSG00000085365(SCAMP1)	--	30.75479215	1696	31.93075876	1625	33.10168049	1770	31.98357437	1731	27.11211314	1453	27.49306426	1455	0.985397916	-0.001361488	normal	0.970305031	-0.182651695	normal	0.926073554	-0.290747198	normal	0.432639805	-0.155786078	normal	--	--	Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SCAMP family	Secretory carrier-associated membrane protein 1 GN=SCAMP1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: secretory carrier-associated membrane protein 1 [Tupaia chinensis]
ENSG00000085377(PREP)	--	18.83302765	927	18.21468004	907	18.691552	908	19.18157707	951	17.272016	832	14.06636556	692	0.978802481	0.006033865	normal	0.967618269	-0.145691847	normal	0.718872956	-0.399447193	normal	0.42617991	-0.169950875	normal	[E]	Amino acid transport and metabolism	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Molecular Function: serine-type exopeptidase activity (GO:0070008);; 	"K01322|0|hsa:5550|PREP, PE, PEP; prolyl endopeptidase (EC:3.4.21.26); K01322 prolyl oligopeptidase [EC:3.4.21.26] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Prolyl oligopeptidase, N-terminal beta-propeller domain;; Prolyl oligopeptidase family"	Prolyl endopeptidase GN=PREP OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	prolyl endopeptidase [Sus scrofa] 
ENSG00000085382(HACE1)	--	3.391505643	244	3.345082986	244	3.712736	252	2.493945045	180	2.984609329	205	2.645497928	182	0.696893941	-0.466283225	normal	0.922310528	-0.27084972	normal	0.672972531	-0.474411555	normal	0.157255696	-0.405207531	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	K12166|0|pps:100982583|HACE1; HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1; K12166 E3 ubiquitin-protein ligase HACE1 [EC:6.3.2.19] (A)	--	[OK]	"Posttranslational modification, protein turnover, chaperones;; Transcription"	HECT-domain (ubiquitin-transferase);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	E3 ubiquitin-protein ligase HACE1 GN=HACE1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: E3 ubiquitin-protein ligase HACE1 isoform X2 [Pteropus alecto] 
ENSG00000085415(SEH1L)	--	19.8505772	794	16.92926712	684	21.92744511	854	16.97678065	697	19.06613517	798	21.05241078	843	0.946766017	-0.218361211	normal	0.952642205	0.20055502	normal	0.977430812	-0.026946852	normal	0.962333677	-0.016592757	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K16725|0|cjc:100895681|SEH1L; centrosomal protein of 192 kDa; K16725 centrosomal protein CEP192 (A)	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	"WD domain, G-beta repeat"	Nucleoporin SEH1 GN=SEH1L OS=Homo sapiens (Human) PE=1 SV=3	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nucleoporin SEH1 isoform X1 [Equus przewalskii]
ENSG00000085433(WDR47)	--	3.978231611	284	3.51599956	252	4.16116	295	4.880097567	346	4.54961668	326	3.849545533	274	0.926152265	0.252808188	normal	0.856119858	0.348180174	normal	0.961732566	-0.114222771	normal	0.60106109	0.165333265	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 47 GN=WDR47 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 47 isoform 1 [Ceratotherium simum simum]
ENSG00000085449(WDFY1)	--	19.72532906	1477	19.49494439	1469	19.95884832	1479	16.03682868	1209	14.941046	1115	15.670214	1173	0.891281028	-0.319319961	normal	0.684137611	-0.41872074	normal	0.859912637	-0.342316527	normal	0.023580653	-0.360862631	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat;; FYVE zinc finger"	WD repeat and FYVE domain-containing protein 1 GN=WDFY1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat and FYVE domain-containing protein 1 [Ovis aries]
ENSG00000085465(OVGP1)	--	0.196891	8	0.367006	15	0.267076	10	0.17163	7	0.626769	25	0.710176	29	--	--	--	0.968094103	0.663286968	normal	0.604959161	1.398674444	normal	--	--	--	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K17526|0|hsa:5016|OVGP1, CHIT5, EGP, MUC9, OGP; oviductal glycoprotein 1, 120kDa; K17526 oviduct-specific glycoprotein (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 18	Oviduct-specific glycoprotein (Precursor) GN=OVGP1 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: oviduct-specific glycoprotein [Ceratotherium simum simum]
ENSG00000085491(SLC25A24)	--	22.54431858	1271	22.68623133	1288	22.64732658	1294	32.35520085	1842	28.14871299	1586	25.60235729	1409	0.319592401	0.503968147	normal	0.932149477	0.278538449	normal	0.978241153	0.114414377	normal	0.061877275	0.306130199	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K14684|0|hsa:29957|SLC25A24, APC1, SCAMC-1; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 24; K14684 solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41 (A)"	--	[F]	Nucleotide transport and metabolism	Mitochondrial carrier protein;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region;; Cytoskeletal-regulatory complex EF hand	Calcium-binding mitochondrial carrier protein SCaMC-1 GN=SLC25A24 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	calcium-binding mitochondrial carrier protein SCaMC-1-like [Sus scrofa] 
ENSG00000085511(MAP3K4)	--	4.02191163	443	4.385129537	474	4.33800152	481	4.797536712	502	5.15990734	569	4.1872089	479	0.959606196	0.149062543	normal	0.931670087	0.241411248	normal	0.971350038	-0.01425776	normal	0.643745166	0.12773133	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04428|0|pps:100981441|MAP3K4; mitogen-activated protein kinase kinase kinase 4; K04428 mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25] (A)	MAPK signaling pathway (ko04010);; GnRH signaling pathway (ko04912)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Mitogen-activated protein kinase kinase kinase 4 GN=MAP3K4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 4 isoform 1 [Ceratotherium simum simum]
ENSG00000085514(PILRA)	--	18.02183489	1432	21.68515449	1633	18.32707952	1479	11.53787603	966	14.37967483	1110	18.2018554	1511	0.062343446	-0.597981916	normal	0.106574082	-0.577738394	normal	0.983888346	0.022567336	normal	0.174143941	-0.361122081	normal	--	--	--	"K15411|3.68933e-159|hsa:29992|PILRA, FDF03; paired immunoglobin-like type 2 receptor alpha; K15411 paired immunoglobulin-like type 2 receptor alpha (A)"	Herpes simplex infection (ko05168)	--	--	Immunoglobulin V-set domain	Paired immunoglobulin-like type 2 receptor alpha (Precursor) GN=PILRA OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: paired immunoglobulin-like type 2 receptor alpha [Camelus bactrianus]
ENSG00000085552(IGSF9)	--	0.156351265	12	0.15295866	11	0.131763535	6	0.05248628	4	0.162643068	12	0.103156812	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Fibronectin type III domain;; CD80-like C2-set immunoglobulin domain	Protein turtle homolog A (Precursor) GN=IGSF9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein turtle homolog A [Camelus dromedarius]
ENSG00000085563(ABCB1)	--	1.710017	158	1.95114932	181	1.76724955	160	0.875075612	79	1.7813358	161	1.74079013	157	0.0058004	-1.016561752	down	0.951522197	-0.188682887	normal	0.967187187	-0.035262319	normal	0.416125246	-0.349255228	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05658|0|hsa:5243|ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1; ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44); K05658 ATP-binding cassette, subfamily B (MDR/TAP), member 1 [EC:3.6.3.44] (A)"	ABC transporters (ko02010);; Bile secretion (ko04976);; MicroRNAs in cancer (ko05206)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"ABC transporter transmembrane region;; ABC transporter;; RecF/RecN/SMC N terminal domain;; Predicted ATPase of the ABC class;; AAA domain;; AAA ATPase domain;; AAA domain;; Protein of unknown function, DUF258;; ATPase family associated with various cellular activities (AAA);; P-loop containing region of AAA domain;; AAA domain;; AAA domain;; Rad17 cell cycle checkpoint protein;; AAA domain (dynein-related subfamily);; Zeta toxin"	Multidrug resistance protein 1 GN=ABCB1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	multidrug resistance protein 1 [Felis catus] 
ENSG00000085644(ZNF213)	--	5.660860032	294	4.142522503	231	5.09163948	288	4.576255144	270	5.268108233	317	6.2792541	377	0.956239765	-0.152855081	normal	0.724927014	0.432736053	normal	0.804742583	0.37846233	normal	0.453393299	0.225817463	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:7760|ZNF213, CR53, ZKSCAN21, ZSCAN53; zinc finger protein 213; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 213 GN=ZNF213 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 213 [Ceratotherium simum simum]
ENSG00000085662(AKR1B1)	--	1588.15	40995	947.791	24887	1425.51	37234	1443.67	37455	1543.97	39458	1818.3	46922	0.997960114	-0.161115582	normal	0.11512188	0.643467633	normal	0.989179222	0.325340659	normal	0.505668264	0.243955963	normal	[R]	General function prediction only	--	"K00011|0|hsa:231|AKR1B1, ADR, ALDR1, ALR2, AR; aldo-keto reductase family 1, member B1 (aldose reductase) (EC:1.1.1.21); K00011 aldehyde reductase [EC:1.1.1.21] (A)"	Pentose and glucuronate interconversions (ko00040);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Glycerolipid metabolism (ko00561)	[R]	General function prediction only	Aldo/keto reductase family	Aldose reductase GN=AKR1B1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: aldose reductase isoform X1 [Lipotes vexillifer]
ENSG00000085719(CPNE3)	--	37.01935608	2672	39.1186951	2443	37.6748256	2599	39.94316673	2744	34.03757607	2478	32.48533224	2324	0.989447255	0.007523941	normal	0.988371459	-0.000903679	normal	0.979984186	-0.169533627	normal	0.835971011	-0.053425412	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-3 GN=CPNE3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: copine-3 isoform X2 [Physeter catodon]
ENSG00000085721(RRN3)	--	26.12341185	1619	28.3758072	1677	27.22109	1604	25.333716	1582	27.74953854	1683	23.84906383	1442	0.983463395	-0.064124085	normal	0.984759062	-0.016259434	normal	0.974109338	-0.161733512	normal	0.737561593	-0.079432542	normal	--	--	--	K15216|0|ptr:741314|RRN3; RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae); K15216 RNA polymerase I-specific transcription initiation factor RRN3 (A)	--	[K]	Transcription	RNA polymerase I specific transcription initiation factor RRN3	RNA polymerase I-specific transcription initiation factor RRN3 GN=RRN3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: RNA polymerase I-specific transcription initiation factor RRN3 isoform X1 [Oryctolagus cuniculus]
ENSG00000085733(CTTN)	--	105.3673972	6872	117.5372004	7844	109.0174141	7253	135.0343241	8880	122.7648594	7972	131.2765211	8573	0.950770938	0.338930563	normal	0.995284796	0.001925249	normal	0.985790406	0.232886141	normal	0.351079854	0.189385485	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06106|0|hsa:2017|CTTN, EMS1; cortactin; K06106 cortactin (A)"	Tight junction (ko04530);; Bacterial invasion of epithelial cells (ko05100);; Pathogenic Escherichia coli infection (ko05130);; Shigellosis (ko05131);; Proteoglycans in cancer (ko05205)	--	--	Repeat in HS1/Cortactin;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Src substrate cortactin GN=CTTN OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: src substrate cortactin isoform X3 [Tupaia chinensis]
ENSG00000085741(WNT11)	--	1.004303	18	0.055992723	2	0.268433106	4	0.694116892	26	0.560180409	20	0.31612952	12	0.979957076	0.46641413	normal	0.10849223	2.598623677	normal	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K01384|0|ptr:451431|WNT11; wingless-type MMTV integration site family, member 11; K01384 wingless-type MMTV integration site family, member 11 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-11 (Precursor) GN=WNT11 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-11 [Eptesicus fuscus] 
ENSG00000085760(MTIF2)	--	26.83098963	1352	25.1233671	1277	23.83144923	1179	18.96253392	976	18.00123704	901	22.95402299	1173	0.328279569	-0.500301858	normal	0.26214255	-0.52384348	normal	0.981372585	-0.015632045	normal	0.03777782	-0.341080385	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K02519|0|hsa:4528|MTIF2; mitochondrial translational initiation factor 2; K02519 translation initiation factor IF-2 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Translation-initiation factor 2;; Elongation factor Tu domain 2;; Miro-like protein;; 50S ribosome-binding GTPase;; Ras family;; Signal recognition particle receptor beta subunit;; ADP-ribosylation factor family	"Translation initiation factor IF-2, mitochondrial (Precursor) GN=MTIF2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: translation initiation factor IF-2, mitochondrial isoform X2 [Equus przewalskii] "
ENSG00000085788(DDHD2)	--	16.9091956	1189	19.35342992	1214	17.07008206	1054	18.71920641	1229	20.48900958	1205	15.97923827	1044	0.9816128	0.01688248	normal	0.980943454	-0.03212167	normal	0.979991036	-0.022012862	normal	0.972547334	-0.013139097	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K16545|0|hsa:23259|DDHD2, SAMWD1, SPG54, iPLA(1)gamma; DDHD domain containing 2; K16545 phospholipase DDHD2 [EC:3.1.1.-] (A)"	--	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	DDHD domain;; WWE domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Phospholipase DDHD2 GN=DDHD2 OS=Homo sapiens (Human) PE=1 SV=2	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: phospholipase DDHD2 isoform X1 [Galeopterus variegatus]
ENSG00000085831(TTC39A)	--	2.036743562	81	1.924128001	98	1.789071821	65	2.790829206	144	4.030263353	179	2.79247921	138	0.168597699	0.787894482	normal	0.048158524	0.837976453	normal	0.00718557	1.060547146	up	0.00557648	0.896121969	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF3808);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 39A GN=TTC39A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 39A isoform X4 [Galeopterus variegatus]
ENSG00000085832(EPS15)	--	10.03283301	889	9.836082044	862	9.292873296	810	10.77766293	964	9.327973512	829	10.52675767	939	0.975667785	0.085874922	normal	0.974624476	-0.077603482	normal	0.954606284	0.204556802	normal	0.786760395	0.071784155	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12472|0|pon:100453749|EPS15; epidermal growth factor receptor pathway substrate 15; K12472 epidermal growth factor receptor substrate 15 (A)	Endocytosis (ko04144)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Cytoskeletal-regulatory complex EF hand;; EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair	Epidermal growth factor receptor substrate 15 GN=EPS15 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor receptor substrate 15 isoform X1 [Felis catus]
ENSG00000085840(ORC1)	--	7.816895655	580	7.420483644	543	8.652769174	639	5.9358806	450	7.145065171	534	6.263571432	472	0.738589655	-0.395766225	normal	0.970933724	-0.045411477	normal	0.591439686	-0.444092796	normal	0.158361145	-0.2959254	normal	[LO]	"Replication, recombination and repair;; Posttranslational modification, protein turnover, chaperones"	Molecular Function: chromatin binding (GO:0003682);; Molecular Function: ATP binding (GO:0005524);; 	"K02603|0|hsa:4998|ORC1, HSORC1, ORC1L, PARC1; origin recognition complex, subunit 1; K02603 origin recognition complex subunit 1 (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	"BAH domain;; ATPase family associated with various cellular activities (AAA);; CDC6, C terminal;; AAA domain;; AAA ATPase domain;; Uncharacterized conserved protein (DUF2075)"	Origin recognition complex subunit 1 GN=ORC1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: origin recognition complex subunit 1 isoform X2 [Camelus ferus]
ENSG00000085871(MGST2)	--	35.75759	328	42.3781	399	36.77435	334	49.74709	475	43.96854216	424	49.066766	485	0.433534714	0.501437795	normal	0.967169764	0.066006257	normal	0.335409437	0.527850769	normal	0.10247278	0.362049138	normal	--	--	--	K00799|5.87369e-88|pps:100982549|MGST2; microsomal glutathione S-transferase 2; K00799 glutathione S-transferase [EC:2.5.1.18] (A)	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	--	--	MAPEG family	Microsomal glutathione S-transferase 2 GN=MGST2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: microsomal glutathione S-transferase 2 [Panthera tigris altaica] 
ENSG00000085872(CHERP)	--	11.75852	1068	11.07116	995	12.11813	1114	12.258612	1103	13.4434	1224	11.60218	1065	0.980403881	0.015666703	normal	0.925394828	0.277028369	normal	0.978614633	-0.073085761	normal	0.772129271	0.073399338	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; 	K12841|0|cfa:610237|CHERP; calcium homeostasis endoplasmic reticulum protein; K12841 calcium homeostasis endoplasmic reticulum protein (A)	Spliceosome (ko03040)	[R]	General function prediction only	Surp module;; G-patch domain;; RNA polymerase II-binding domain.	Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: calcium homeostasis endoplasmic reticulum protein isoform X1 [Canis lupus familiaris]
ENSG00000085978(ATG16L1)	--	12.14555834	799	12.0972261	805	12.67061297	830	8.6686165	565	9.3534195	584	8.526338044	544	0.247357314	-0.52955916	normal	0.439304923	-0.483375864	normal	0.05838403	-0.616398298	normal	0.001090206	-0.544959241	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K17890|0|mcf:102117153|ATG16L1; autophagy related 16-like 1 (S. cerevisiae); K17890 autophagy-related protein 16, animal type (A)"	Regulation of autophagy (ko04140)	[R]	General function prediction only	"Autophagy protein 16 (ATG16);; WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Autophagy-related protein 16-1 GN=ATG16L1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: autophagy-related protein 16-1 isoform X1 [Galeopterus variegatus]
ENSG00000085982(USP40)	--	16.13154518	1647	14.07388281	1606	14.0610981	1570	11.61238243	1297	12.984513	1424	13.09995832	1467	0.801965747	-0.375098924	normal	0.967435216	-0.194754404	normal	0.980436149	-0.106081399	normal	0.207569232	-0.224524464	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11869|0|hsa:55230|USP40; ubiquitin specific peptidase 40 (EC:3.4.19.12); K11869 ubiquitin carboxyl-terminal hydrolase 40 [EC:3.4.19.12] (A)	--	--	--	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 40 GN=USP40 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 40 [Equus caballus]
ENSG00000085998(POMGNT1)	--	23.69592096	1313	21.28458327	1194	23.57217739	1330	22.57133835	1237	20.1931099	1107	19.09421278	1061	0.977200057	-0.116712938	normal	0.9739101	-0.130402587	normal	0.868214884	-0.333867049	normal	0.312255482	-0.193874271	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; 	"K09666|0|hsa:55624|POMGNT1, GNTI.2, GnT_I.2, LGMD2O, MEB, MGAT1.2, gnT-I.2; protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) (EC:2.4.1.-); K09666 beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.-] (A)"	Other types of O-glycan biosynthesis (ko00514)	--	--	GNT-I family	"Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 GN=POMGNT1 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 [Ursus maritimus]"
ENSG00000085999(RAD54L)	--	5.254467042	249	4.31600388	244	6.227851	330	4.8112569	223	3.7956556	194	3.9890112	184	0.949756383	-0.188703068	normal	0.871135449	-0.34981365	normal	0.004017369	-0.845786328	normal	0.069841131	-0.474781938	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: histone deacetylation (GO:0016575);; Molecular Function: hydrolase activity (GO:0016787);; Cellular Component: HDA1 complex (GO:0070823);; 	"K10875|0|hsa:8438|RAD54L, HR54, RAD54A, hHR54, hRAD54; RAD54-like (S. cerevisiae); K10875 DNA repair and recombination protein RAD54 and RAD54-like protein [EC:3.6.4.-] (A)"	Homologous recombination (ko03440)	[L]	"Replication, recombination and repair"	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; Class II histone deacetylase complex subunits 2 and 3;; Type III restriction enzyme, res subunit;; Rad54 N terminal"	DNA repair and recombination protein RAD54-like GN=RAD54L OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA repair and recombination protein RAD54-like [Galeopterus variegatus]
ENSG00000086015(MAST2)	--	11.683868	1396	13.24492246	1625	13.22866999	1644	13.7802047	1646	12.7798752	1511	14.48788493	1782	0.96454241	0.206623529	normal	0.978678544	-0.126240744	normal	0.981746255	0.107900239	normal	0.809572548	0.061471086	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08789|0|hsa:23139|MAST2, MAST205, MTSSK; microtubule associated serine/threonine kinase 2 (EC:2.7.11.1); K08789 microtubule-associated serine/threonine kinase [EC:2.7.11.1] (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	Domain of unknown function (DUF1908);; Protein kinase domain;; Protein tyrosine kinase;; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Microtubule-associated serine/threonine-protein kinase 2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: microtubule-associated serine/threonine-protein kinase 2 [Ceratotherium simum simum]
ENSG00000086061(DNAJA1)	--	114.2970141	4875	145.28939	6338	143.484061	6135	178.87482	7796	145.712878	6182	141.4250128	6040	0.029053003	0.646337179	normal	0.993918661	-0.057366703	normal	0.994255001	-0.030798585	normal	0.49309343	0.184595133	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: heat shock protein binding (GO:0031072);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K09502|0|umr:103667028|DNAJA1; DnaJ (Hsp40) homolog, subfamily A, member 1; K09502 DnaJ homolog subfamily A member 1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain;; DnaJ central domain	DnaJ homolog subfamily A member 1 (Precursor) GN=DNAJA1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: LOW QUALITY PROTEIN: DnaJ (Hsp40) homolog, subfamily A, member 1 [Dasypus novemcinctus]"
ENSG00000086062(B4GALT1)	--	109.7050003	7170	104.5960006	6818	103.4530003	6714	162.9160004	10619	175.4400004	11419	170.3010003	11165	0.361999594	0.535675763	normal	0.005779675	0.722464133	normal	0.003843681	0.725319338	normal	1.56E-05	0.660471398	normal	--	--	--	"K07966|0|hsa:2683|B4GALT1, B4GAL-T1, CDG2D, GGTB2, GT1, GTB, beta4Gal-T1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 (EC:2.4.1.22 2.4.1.90 2.4.1.38); K07966 beta-1,4-galactosyltransferase 1 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-] (A)"	Galactose metabolism (ko00052);; N-Glycan biosynthesis (ko00510);; Other types of O-glycan biosynthesis (ko00514);; Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	N-terminal region of glycosyl transferase group 7;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	"Processed beta-1,4-galactosyltransferase 1 GN=B4GALT1 OS=Homo sapiens (Human) PE=1 SV=5"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-galactosyltransferase 1 isoform X2 [Oryctolagus cuniculus]"
ENSG00000086065(CHMP5)	--	55.3331231	1381	52.137466	1311	55.37541914	1375	54.573129	1381	53.555517	1333	51.43466651	1290	0.982867769	-0.030797999	normal	0.98228729	0.002579586	normal	0.979273526	-0.100238152	normal	0.874611439	-0.043867743	normal	--	--	Biological Process: vacuolar transport (GO:0007034);; 	K12198|3.62868e-124|ptr:746713|CHMP5; charged multivesicular body protein 5; K12198 charged multivesicular body protein 5 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snf7	Charged multivesicular body protein 5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 5 [Elephantulus edwardii]
ENSG00000086102(NFX1)	--	9.84392	907	12.38223	1116	11.19657	990	11.59668	1035	11.43537	1012	13.91926	1249	0.967295962	0.159371201	normal	0.967949199	-0.162323189	normal	0.87585327	0.326536571	normal	0.663683138	0.108785186	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	"K12236|0|ptr:465042|NFX1; nuclear transcription factor, X-box binding 1; K12236 transcriptional repressor NF-X1 [EC:6.3.2.-] (A)"	--	[K]	Transcription	NF-X1 type zinc finger;; R3H domain	Transcriptional repressor NF-X1 GN=NFX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcriptional repressor NF-X1 [Galeopterus variegatus]
ENSG00000086159(AQP6)	--	0.050825071	2	0	0	0.0709541	0	0.050400016	2	0	0	0.0418396	1	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K09868|9.52644e-176|hsa:363|AQP6, AQP2L, KID; aquaporin 6, kidney specific; K09868 aquaporin-6 (A)"	--	[G]	Carbohydrate transport and metabolism	Major intrinsic protein	Aquaporin-6 GN=AQP6 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-6 isoform X2 [Tupaia chinensis] 
ENSG00000086189(DIMT1)	--	17.893355	672	17.185	644	20.4731	758	18.598265	709	19.0994	726	15.4359	589	0.974321866	0.046388872	normal	0.963173252	0.151147866	normal	0.788307789	-0.371378795	normal	0.850390153	-0.056610536	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K14191|0|ptr:461851|DIMT1, DIMT1L; DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae); K14191 18S rRNA (adenine1779-N6/adenine1780-N6)-dimethyltransferase [EC:2.1.1.183] (A)"	--	[A]	RNA processing and modification	Ribosomal RNA adenine dimethylase;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase small domain	Probable dimethyladenosine transferase GN=DIMT1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable dimethyladenosine transferase [Leptonychotes weddellii]
ENSG00000086200(IPO11)	--	11.22636326	801	12.37435681	880	11.81460526	845	11.01633959	772	10.22281983	704	11.33736407	770	0.973756983	-0.083869772	normal	0.846050125	-0.342694684	normal	0.967622527	-0.142117785	normal	0.362871703	-0.190744112	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Importin-beta N-terminal domain	Importin-11 GN=IPO11 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin-11 isoform X1 [Camelus ferus] 
ENSG00000086232(EIF2AK1)	--	58.026498	4268	53.70066	3665	62.080307	4188	54.930322	3977	60.353749	4324	62.649416	4092	0.989025174	-0.132662388	normal	0.979403757	0.217044239	normal	0.992079105	-0.041731494	normal	0.975714352	0.011081544	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16194|0|hsa:27102|EIF2AK1, HCR, HRI; eukaryotic translation initiation factor 2-alpha kinase 1 (EC:2.7.11.1); K16194 eukaryotic translation initiation factor 2-alpha kinase 1 [EC:2.7.11.1] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[J]	"Translation, ribosomal structure and biogenesis"	Protein kinase domain;; Protein tyrosine kinase	Eukaryotic translation initiation factor 2-alpha kinase 1 GN=EIF2AK1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 1 [Ceratotherium simum simum]
ENSG00000086288(NME8)	--	73.30674002	2277	75.0874887	2362	70.77487287	2156	62.43476286	2136	63.96359158	1980	72.58358468	2229	0.98350666	-0.122969214	normal	0.94676791	-0.275741978	normal	0.987320289	0.039720594	normal	0.571109797	-0.120088308	normal	[F]	Nucleotide transport and metabolism	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[F]	Nucleotide transport and metabolism	Nucleoside diphosphate kinase;; Thioredoxin	Thioredoxin domain-containing protein 3 GN=NME8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin domain-containing protein 3 [Galeopterus variegatus]
ENSG00000086300(SNX10)	--	5.986836791	207	6.786615255	214	6.408524342	212	8.278907499	290	7.457106274	256	7.175357597	247	0.693917224	0.452739202	normal	0.935552154	0.235582677	normal	0.944690772	0.210761237	normal	0.307544477	0.303415874	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17924|2.46239e-112|mcc:701684|SNX10; sorting nexin 10; K17924 sorting nexin-10/11 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain	Sorting nexin-10 GN=SNX10 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-10 [Ceratotherium simum simum]
ENSG00000086475(SEPHS1)	--	35.27729069	1452	32.99978597	1552	29.09895582	1429	34.564219	1613	37.56715718	1707	38.30363746	1681	0.97921873	0.120751461	normal	0.980126506	0.115800325	normal	0.959253202	0.225801818	normal	0.445163508	0.15278861	normal	--	--	--	"K01008|0|ptr:736796|SEPHS1; selenophosphate synthetase 1 (EC:2.7.9.3); K01008 selenide, water dikinase [EC:2.7.9.3] (A)"	Selenocompound metabolism (ko00450)	[T]	Signal transduction mechanisms	"AIR synthase related protein, C-terminal domain;; AIR synthase related protein, N-terminal domain"	"Selenide, water dikinase 1 GN=SEPHS1 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"selenide, water dikinase 1 [Canis lupus familiaris] "
ENSG00000086504(MRPL28)	--	64.2851812	1269	60.04918252	1222	66.76767961	1371	65.86502903	1330	67.96954899	1312	60.270888	1205	0.982055933	0.036858322	normal	0.979519808	0.081000124	normal	0.96472746	-0.194258134	normal	0.928019045	-0.026897367	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; 	"K02902|2.81568e-178|hsa:10573|MRPL28, MAAT1, p15; mitochondrial ribosomal protein L28; K02902 large subunit ribosomal protein L28 (A)"	Ribosome (ko03010)	[S]	Function unknown	--	"39S ribosomal protein L28, mitochondrial (Precursor) GN=MRPL28 OS=Homo sapiens (Human) PE=1 SV=4"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L28, mitochondrial isoform X1 [Myotis brandtii] "
ENSG00000086506(HBQ1)	--	10.8182	55	9.13135	49	12.0686	66	9.99764	54	17.6512	90	6.10029	32	0.977735165	-0.055733155	normal	0.375189424	0.836402304	normal	0.295032174	-1.018471418	normal	0.986272296	0.02857326	normal	--	--	Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; 	K13827|2.91082e-88|ggo:101145911|HBQ1; hemoglobin subunit theta-1; K13827 hemoglobin subunit theta (A)	--	[C]	Energy production and conversion	Globin	Hemoglobin subunit theta-1 GN=HBQ1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: hemoglobin subunit theta-1 [Galeopterus variegatus]
ENSG00000086544(ITPKC)	--	5.64999	441	5.7415	459	5.55095	445	6.68004	521	6.4249	496	7.42903	580	0.94448236	0.209001961	normal	0.966782378	0.090133694	normal	0.790606188	0.372843179	normal	0.336379449	0.226832856	normal	--	--	"Molecular Function: inositol-1,4,5-trisphosphate 3-kinase activity (GO:0008440);; "	"K00911|0|hsa:80271|ITPKC, IP3-3KC, IP3KC; inositol-trisphosphate 3-kinase C (EC:2.7.1.127); K00911 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] (A)"	Inositol phosphate metabolism (ko00562);; Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070)	[I]	Lipid transport and metabolism	Inositol polyphosphate kinase	Inositol-trisphosphate 3-kinase C GN=ITPKC OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: inositol-trisphosphate 3-kinase C [Ceratotherium simum simum]
ENSG00000086548(CEACAM6)	--	0.02055462	1	0.293408584	16	0.462751054	15	3.867981581	201	4.206932034	218	1.528545252	80	0	6.297863297	up	0	3.627434729	up	2.63E-07	2.29564269	up	3.12E-05	3.940514809	up	--	--	--	"K06499|0|hsa:4680|CEACAM6, CD66c, CEAL, NCA; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); K06499 carcinoembryonic antigen-related cell adhesion molecule (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Carcinoembryonic antigen-related cell adhesion molecule 6 (Precursor) GN=CEACAM6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 8 [Ceratotherium simum simum]
ENSG00000086570(FAT2)	--	0.019842609	2	0.117198009	12	0.048068612	4	0.089514435	11	0.057919403	8	0.019534094	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16506|0|hsa:2196|FAT2, CDHF8, CDHR9, HFAT2, MEGF1; FAT atypical cadherin 2; K16506 protocadherin Fat 1/2/3 (A)"	--	[T]	Signal transduction mechanisms	Cadherin domain;; Cadherin-like;; Laminin G domain;; Laminin G domain;; EGF-like domain	Protocadherin Fat 2 (Precursor) GN=FAT2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protocadherin Fat 2 [Galeopterus variegatus]
ENSG00000086589(RBM22)	--	16.01364199	773	21.03837321	1011	16.99170872	817	17.28393277	840	17.93811411	871	19.09893552	937	0.973663569	0.088919085	normal	0.944072277	-0.23608405	normal	0.959158399	0.189094457	normal	0.991919426	0.004765624	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K12872|0|umr:103664592|RBM22; RNA binding motif protein 22; K12872 pre-mRNA-splicing factor RBM22/SLT11 (A)	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Pre-mRNA-splicing factor RBM22 GN=RBM22 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	pre-mRNA-splicing factor RBM22 [Bos taurus] 
ENSG00000086598(TMED2)	--	141.6418104	4899	147.170118	5090	142.6386812	4861	186.7154722	6518	177.1878741	6102	184.2582018	6378	0.889432076	0.381005904	normal	0.980191022	0.240124733	normal	0.884174806	0.383455069	normal	0.044624047	0.334048939	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 2 (Precursor) GN=TMED2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 2 [Eptesicus fuscus]
ENSG00000086619(ERO1B)	--	5.304054	334	4.198464	257	4.528005	263	3.469466	204	3.378548948	209	4.098745004	244	0.027316811	-0.737721589	normal	0.893993536	-0.317615333	normal	0.961380191	-0.115781714	normal	0.133670677	-0.399150903	normal	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	"Molecular Function: protein disulfide isomerase activity (GO:0003756);; Cellular Component: endoplasmic reticulum (GO:0005783);; Molecular Function: oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor (GO:0016671);; Biological Process: oxidation-reduction process (GO:0055114);; "	K10976|0|hsa:56605|ERO1LB; ERO1-like beta (S. cerevisiae); K10976 ERO1-like protein beta [EC:1.8.4.-] (A)	Protein processing in endoplasmic reticulum (ko04141)	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Endoplasmic Reticulum Oxidoreductin 1 (ERO1)	ERO1-like protein beta (Precursor) GN=ERO1LB OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ERO1-like protein beta [Loxodonta africana]
ENSG00000086666(ZFAND6)	--	124.2529366	2236	125.2008769	2223	119.3885963	2109	101.5043857	1929	116.6535007	2022	111.7482194	2064	0.959508823	-0.243718797	normal	0.979214175	-0.158038726	normal	0.986878122	-0.039379022	normal	0.459582476	-0.147959161	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	A20-like zinc finger;; AN1-like Zinc finger	AN1-type zinc finger protein 6 GN=ZFAND6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: AN1-type zinc finger protein 6 isoform 1 [Ceratotherium simum simum] 
ENSG00000086712(TXLNG)	--	9.610403501	823	9.538021462	815	9.9404308	838	12.16765391	1048	11.0744	946	9.934294084	853	0.88123649	0.317316114	normal	0.957729951	0.193280438	normal	0.977556665	0.017273159	normal	0.385071298	0.179659498	normal	--	--	Molecular Function: syntaxin binding (GO:0019905);; 	--	--	[Z]	Cytoskeleton	Myosin-like coiled-coil protein	Gamma-taxilin GN=TXLNG OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: gamma-taxilin isoform X1 [Galeopterus variegatus]
ENSG00000086717(PPEF1)	--	1.06252546	65	0.65486021	38	0.82298602	47	0.218848696	13	0.673793432	23	0.607304256	32	8.22E-06	-2.223315354	down	0.922646095	-0.709151862	normal	0.942869118	-0.54163516	normal	0.025660071	-1.160018205	normal	[T]	Signal transduction mechanisms	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Molecular Function: hydrolase activity (GO:0016787);; 	"K13807|0|hsa:5475|PPEF1, PP7, PPEF, PPP7C, PPP7CA; protein phosphatase, EF-hand calcium binding domain 1 (EC:3.1.3.16); K13807 serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Calcineurin-like phosphoesterase;; EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF hand;; EF-hand domain;; PPP5 TPR repeat region;; IQ calmodulin-binding motif	Serine/threonine-protein phosphatase with EF-hands 1 GN=PPEF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein phosphatase with EF-hands 1 [Odobenus rosmarus divergens]
ENSG00000086730(LAT2)	--	1.910278571	68	2.25824259	50	1.184749909	45	0.72417511	33	1.041517713	45	0.80857149	33	0.232902861	-1.03945494	normal	0.975388838	-0.168068435	normal	0.961615304	-0.438476777	normal	0.312683427	-0.575726991	normal	--	--	Biological Process: immune response-regulating signaling pathway (GO:0002764);; Biological Process: B cell activation (GO:0042113);; 	--	--	--	--	--	Linker for activation of T-cells family member 2 GN=HSPC046 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: linker for activation of T-cells family member 2 isoform X1 [Equus caballus]
ENSG00000086758(HUWE1)	--	40.53679718	12027	41.29112749	12186	40.3464624	12514	42.97848114	12542	42.88753035	12742	43.72279376	13393	0.996803894	0.029654628	normal	0.996624075	0.042935328	normal	0.996402897	0.089634234	normal	0.85524416	0.053700087	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	"K10592|0|mdo:100010537|HUWE1; HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase; K10592 E3 ubiquitin-protein ligase HUWE1 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[OK]	"Posttranslational modification, protein turnover, chaperones;; Transcription"	Domain of Unknown Function (DUF913);; HECT-domain (ubiquitin-transferase);; Domain of Unknown Function (DUF908);; Domain of unknown function (DUF4414);; WWE domain;; UBA/TS-N domain	E3 ubiquitin-protein ligase HUWE1 GN=HUWE1 OS=Homo sapiens (Human) PE=1 SV=3	KO	"Transcription;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase HUWE1 isoform X12 [Monodelphis domestica]
ENSG00000086827(ZW10)	--	7.016176354	364	8.48375	386	7.888205075	397	8.891450272	467	9.967694623	493	7.55431506	402	0.865060949	0.327429074	normal	0.861932561	0.330412323	normal	0.969745431	0.009728226	normal	0.366093209	0.226394263	normal	--	--	"Biological Process: mitotic cell cycle (GO:0000278);; Cellular Component: chromosome, centromeric region (GO:0000775);; Cellular Component: nucleus (GO:0005634);; "	K11578|0|pps:100982328|ZW10; zw10 kinetochore protein; K11578 centromere/kinetochore protein ZW10 (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Centromere/kinetochore Zw10	Centromere/kinetochore protein zw10 homolog GN=ZW10 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: centromere/kinetochore protein zw10 homolog isoform X1 [Galeopterus variegatus]
ENSG00000086848(ALG9)	--	12.91422052	466	13.58851003	487	13.96998836	485	14.50026651	549	13.98561779	485	13.44611475	481	0.946326961	0.205020647	normal	0.970429164	-0.0272787	normal	0.971321285	-0.020176123	normal	0.874611439	0.053651018	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K03846|0|pps:100995778|ALG9; ALG9, alpha-1,2-mannosyltransferase; K03846 alpha-1,2-mannosyltransferase [EC:2.4.1.259 2.4.1.261] (A)"	N-Glycan biosynthesis (ko00510)	[MU]	"Cell wall/membrane/envelope biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	Alg9-like mannosyltransferase family	"Alpha-1,2-mannosyltransferase ALG9 GN=ALG9 OS=Homo sapiens (Human) PE=1 SV=2"	MU	"Cell wall/membrane/envelope biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: alpha-1,2-mannosyltransferase ALG9 isoform 1 [Trichechus manatus latirostris]"
ENSG00000086991(NOX4)	--	0	0	0	0	0	0	0.049753315	3	0.8409567	9	0.069271694	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[PQ]	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Ferric reductase NAD binding domain;; Ferric reductase like transmembrane component;; FAD-binding domain	NADPH oxidase 4 GN=NOX4 OS=Homo sapiens (Human) PE=1 SV=2	PQ	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: NADPH oxidase 4 isoform 2 [Ceratotherium simum simum]
ENSG00000087008(ACOX3)	--	5.476763252	326	4.558015614	297	5.555852227	310	5.581348	323	7.3904384	431	5.217157	322	0.967380702	-0.043961909	normal	0.425866697	0.513615973	normal	0.967228383	0.046279501	normal	0.532582686	0.184697495	normal	[I]	Lipid transport and metabolism	"Molecular Function: acyl-CoA oxidase activity (GO:0003997);; Cellular Component: peroxisome (GO:0005777);; Biological Process: fatty acid beta-oxidation (GO:0006635);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00232|0|pps:100973171|ACOX3; acyl-CoA oxidase 3, pristanoyl; K00232 acyl-CoA oxidase [EC:1.3.3.6] (A)"	Fatty acid degradation (ko00071);; alpha-Linolenic acid metabolism (ko00592);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; cAMP signaling pathway (ko04024);; Peroxisome (ko04146)	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	"Acyl-CoA oxidase;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	Peroxisomal acyl-coenzyme A oxidase 3 GN=ACOX3 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: peroxisomal acyl-coenzyme A oxidase 3 isoform X1 [Galeopterus variegatus]
ENSG00000087053(MTMR2)	--	10.36326904	641	13.11781767	798	11.63885113	687	14.93171136	922	13.61835759	835	15.22249048	921	0.374895563	0.49262083	normal	0.975895592	0.043879599	normal	0.675901716	0.413810185	normal	0.086166332	0.311649578	normal	--	--	--	K18081|0|pps:100977094|MTMR2; myotubularin related protein 2; K18081 myotubularin-related protein 1/2 [EC:3.1.3.-] (A)	--	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	Myotubularin-like phosphatase domain;; GRAM domain;; Protein-tyrosine phosphatase	Myotubularin-related protein 2 GN=MTMR2 OS=Homo sapiens (Human) PE=1 SV=4	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: myotubularin-related protein 2 isoform X1 [Lipotes vexillifer]
ENSG00000087074(PPP1R15A)	--	13.13572411	788	16.76169279	1034	13.39274129	808	17.620979	1090	10.71987626	657	23.539092	1435	0.595073753	0.436501951	normal	0.016810811	-0.674448714	normal	0.000234561	0.819166115	normal	0.705490138	0.254126902	normal	--	--	--	"K14019|0|hsa:23645|PPP1R15A, GADD34; protein phosphatase 1, regulatory subunit 15A; K14019 protein phosphatase 1 regulatory subunit 15A (A)"	Protein processing in endoplasmic reticulum (ko04141)	--	--	Phosphatase-1 catalytic subunit binding region	Protein phosphatase 1 regulatory subunit 15A GN=PPP1R15A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 15A [Galeopterus variegatus]
ENSG00000087076(HSD17B14)	--	20.484406	500	21.271775	573	19.98937	506	11.165847	291	12.243117	294	22.36212	632	0.002250987	-0.80844217	normal	2.75E-05	-0.980463158	normal	0.880350234	0.311660657	normal	0.511604827	-0.394638364	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	--	--	[R]	General function prediction only	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; NAD dependent epimerase/dehydratase family	17-beta-hydroxysteroid dehydrogenase 14 GN=HSD17B14 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 17-beta-hydroxysteroid dehydrogenase 14 [Galeopterus variegatus]
ENSG00000087077(TRIP6)	--	23.64553094	804	32.54763001	1211	27.98050261	1061	28.70197003	1026	26.72142019	922	29.720796	1021	0.876870615	0.320387975	normal	0.690426764	-0.414191958	normal	0.978564428	-0.063640755	normal	0.847712546	-0.072319396	normal	--	--	--	"K14429|0|mcc:713119|SLC12A9; solute carrier family 12 (potassium/chloride transporters), member 9; K14429 solute carrier family 12 (potassium/chloride transporters), member 9 (A)"	--	[T]	Signal transduction mechanisms	LIM domain	Thyroid receptor-interacting protein 6 GN=TRIP6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: thyroid receptor-interacting protein 6 isoform X1 [Equus caballus]
ENSG00000087085(ACHE)	--	0.732781652	26	0.238177465	11	0.32638735	11	1.64354087	62	1.308895871	53	0.465161899	18	0.150867008	1.176641908	normal	0.000338995	2.103401685	up	--	--	--	0.145146294	1.445603894	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	K01049|0|pps:100980268|ACHE; acetylcholinesterase (Yt blood group); K01049 acetylcholinesterase [EC:3.1.1.7] (A)	Glycerophospholipid metabolism (ko00564);; Cholinergic synapse (ko04725)	[T]	Signal transduction mechanisms	Carboxylesterase family;; alpha/beta hydrolase fold	Acetylcholinesterase (Precursor) GN=ACHE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: acetylcholinesterase isoform X1 [Galeopterus variegatus]
ENSG00000087086(FTL)	--	8116.16	95411	10175.1	119718	8905.3	107021	7802.47	93676	7501.28	87816	11360.4	135985	0.999413786	-0.057307464	normal	0.94956644	-0.468503974	normal	0.994769662	0.337257928	normal	0.940283296	-0.04122752	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cellular iron ion homeostasis (GO:0006879);; Molecular Function: ferric iron binding (GO:0008199);; 	"K13625|1.10325e-115|nle:100592671|FTL; ferritin, light polypeptide; K13625 ferritin light chain (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Ferritin-like domain	Ferritin light chain GN=FTL OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: ferritin light chain [Mustela putorius furo] 
ENSG00000087087(SRRT)	--	27.76255108	1930	31.09716283	2153	30.23789789	2156	32.64333263	2256	32.4147444	2218	26.59431138	1856	0.973389515	0.194190866	normal	0.98723081	0.021469631	normal	0.965253542	-0.224282182	normal	1	-0.000758988	normal	--	--	--	--	--	[R]	General function prediction only	Arsenite-resistance protein 2;; Domain of unknown function (DUF3546)	Serrate RNA effector molecule homolog GN=SRRT OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: serrate RNA effector molecule homolog isoform X1 [Elephantulus edwardii]
ENSG00000087088(BAX)	--	279.2836237	3465	291.5253184	4495	280.56438	4154	307.83696	4336	303.2500002	3770	349.1267113	4688	0.954827505	0.292560978	normal	0.964920235	-0.275081944	normal	0.987178033	0.166122951	normal	0.846429301	0.057796678	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K02159|4.87421e-119|nle:100593013|BAX; BCL2-associated X protein; K02159 apoptosis regulator BAX (A)	Sphingolipid signaling pathway (ko04071);; p53 signaling pathway (ko04115);; Protein processing in endoplasmic reticulum (ko04141);; Apoptosis (ko04210);; Neurotrophin signaling pathway (ko04722);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Prion diseases (ko05020);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Colorectal cancer (ko05210)	--	--	"Apoptosis regulator proteins, Bcl-2 family"	Apoptosis regulator BAX GN=BAX OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: apoptosis regulator BAX isoform X1 [Mustela putorius furo] 
ENSG00000087095(NLK)	--	11.58434579	589	10.39986571	584	11.21596338	611	11.174769	644	10.89884018	600	10.91022152	627	0.969553202	0.097716979	normal	0.972760093	0.017522808	normal	0.973745822	0.028930932	normal	0.883872229	0.04747325	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04468|0|ptr:739132|NLK; nemo-like kinase; K04468 nemo like kinase [EC:2.7.11.24] (A)	MAPK signaling pathway (ko04010);; FoxO signaling pathway (ko04068);; Wnt signaling pathway (ko04310);; Adherens junction (ko04520)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase NLK GN=NLK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase NLK [Oryctolagus cuniculus] 
ENSG00000087111(PIGS)	--	33.13139	1519	28.38287	1265	26.31973	1234	34.98667	1637	38.32701	1644	37.40968	1719	0.982705874	0.077025133	normal	0.846440802	0.356271805	normal	0.470448326	0.469446113	normal	0.075770234	0.294234829	normal	--	--	Biological Process: attachment of GPI anchor to protein (GO:0016255);; Cellular Component: GPI-anchor transamidase complex (GO:0042765);; 	"K05291|0|hsa:94005|PIGS; phosphatidylinositol glycan anchor biosynthesis, class S; K05291 phosphatidylinositol glycan, class S (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[MO]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	Phosphatidylinositol-glycan biosynthesis class S protein	GPI transamidase component PIG-S GN=PIGS OS=Homo sapiens (Human) PE=1 SV=3	MO	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: GPI transamidase component PIG-S [Pteropus alecto] 
ENSG00000087116(ADAMTS2)	--	0	0	0	0	0.0275015	0	0.057907361	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08618|0|hsa:9509|ADAMTS2, ADAM-TS2, ADAMTS-2, ADAMTS-3, NPI, PC_I-NP, PCI-NP, PCINP, PCPNI, PNPI; ADAM metallopeptidase with thrombospondin type 1 motif, 2 (EC:3.4.24.14); K08618 a disintegrin and metalloproteinase with thrombospondin motifs 2 [EC:3.4.24.14] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin family propeptide;; Thrombospondin type 1 domain;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 2 (Precursor) GN=ADAMTS2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 2, partial [Bubalus bubalis]"
ENSG00000087128(TMPRSS11E)	--	0	0	0.0289106	1	0	0	0.0572327	2	0	0	0.057279	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09642|0|hsa:28983|TMPRSS11E, DESC1, TMPRSS11E2; transmembrane protease, serine 11E (EC:3.4.21.-); K09642 transmembrane protease, serine 11E [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; SEA domain;; Domain of unknown function (DUF1986)	Transmembrane protease serine 11E catalytic chain (Precursor) GN=TMPRSS11E OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 11E [Galeopterus variegatus]
ENSG00000087152(ATXN7L3)	--	31.03515846	2132	27.32549066	2117	24.6675888	1829	27.13471983	2060	34.367841	2324	29.3825703	2111	0.985587818	-0.08033646	normal	0.984002835	0.113085123	normal	0.971507891	0.198427226	normal	0.754537813	0.074415637	normal	--	--	--	K11363|0|mcc:714437|ataxin-7-like protein 3-like; K11363 SAGA-associated factor 11 (A)	--	--	--	"Sgf11 (transcriptional regulation protein);; SCA7, zinc-binding domain"	Ataxin-7-like protein 3 {ECO:0000255|HAMAP-Rule:MF_03047} OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ataxin-7-like protein 3 isoform X3 [Pteropus alecto]
ENSG00000087157(PGS1)	--	17.49257838	624	18.5983129	689	20.37866619	683	14.58032251	529	15.42515616	568	15.1292801	633	0.917093632	-0.268391821	normal	0.894484153	-0.299314764	normal	0.968295813	-0.117700739	normal	0.289607458	-0.226933742	normal	[I]	Lipid transport and metabolism	--	K00995|0|hsa:9489|PGS1; phosphatidylglycerophosphate synthase 1 (EC:2.7.8.5); K00995 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase [EC:2.7.8.5] (A)	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	PLD-like domain	"CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial (Precursor) GN=PGS1 OS=Homo sapiens (Human) PE=2 SV=1"	I	Lipid transport and metabolism	"PREDICTED: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase, mitochondrial [Leptonychotes weddellii]"
ENSG00000087191(PSMC5)	--	89.24539327	2365	93.94347387	2495	96.56799442	2546	109.5501001	2942	107.7623453	2776	83.95112626	2226	0.947432315	0.283959138	normal	0.984441522	0.132465051	normal	0.974100386	-0.201941881	normal	0.731740104	0.079269224	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	"K03066|0|cfa:480478|PSMC5; proteasome (prosome, macropain) 26S subunit, ATPase, 5; K03066 26S proteasome regulatory subunit T6 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain (Cdc48 subfamily);; AAA domain (dynein-related subfamily);; AAA domain;; Holliday junction DNA helicase ruvB N-terminus	26S protease regulatory subunit 8 GN=PSMC5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S protease regulatory subunit 8 isoform X2 [Canis lupus familiaris]
ENSG00000087206(UIMC1)	--	13.9865534	714	13.11418441	744	11.97353088	676	13.35153966	710	15.64561726	804	13.93589641	759	0.974961816	-0.03885347	normal	0.972529958	0.090289752	normal	0.963054814	0.158450501	normal	0.802893234	0.069953995	normal	--	--	--	--	--	--	--	--	BRCA1-A complex subunit RAP80 GN=UIMC1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	BRCA1-A complex subunit RAP80 [Sus scrofa] 
ENSG00000087237(CETP)	--	0	0	0.038773217	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: lipid binding (GO:0008289);; 	"K16835|0|hsa:1071|CETP, BPIFF, HDLCQ10; cholesteryl ester transfer protein, plasma; K16835 cholesteryl ester transfer protein (A)"	--	[V]	Defense mechanisms	"LBP / BPI / CETP family, C-terminal domain;; LBP / BPI / CETP family, N-terminal domain"	Cholesteryl ester transfer protein {ECO:0000303|PubMed:3600759} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: cholesteryl ester transfer protein [Tupaia chinensis]
ENSG00000087245(MMP2)	--	1.121701104	82	1.25332676	58	2.330630753	75	3.477586717	181	5.262589924	351	3.2224994	177	0.000868728	1.097287613	up	0	2.545305676	up	0.000129125	1.214085631	up	0.015919881	1.700770026	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K01398|0|ptr:454094|MMP2; matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase); K01398 matrix metalloproteinase-2 (gelatinase A) [EC:3.4.24.24] (A)"	Leukocyte transendothelial migration (ko04670);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Bladder cancer (ko05219)	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Fibronectin type II domain;; Hemopexin;; Putative peptidoglycan binding domain	PEX (Precursor) GN=MMP2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	matrix metalloproteinase 2 [Tupaia belangeri]
ENSG00000087250(MT3)	--	0.283715085	1	0	0	0	0	1.077208191	6	0.369576832	1	0.18458753	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K14740|6.62419e-32|pps:100989519|MT3; metallothionein 3; K14740 metallothionein 3 (A)	--	[P]	Inorganic ion transport and metabolism	Metallothionein	Metallothionein-3 GN=MT3 OS=Homo sapiens (Human) PE=1 SV=1	--	--	--
ENSG00000087253(LPCAT2)	--	7.155651891	497	6.04620108	393	5.204132421	390	5.636356008	394	7.996891834	531	5.37238	338	0.809775719	-0.364613188	normal	0.714679506	0.411389511	normal	0.941629632	-0.21385076	normal	0.945420517	-0.040864652	normal	[I]	Lipid transport and metabolism	"Molecular Function: calcium ion binding (GO:0005509);; Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13510|0|hsa:54947|LPCAT2, AYTL1, LysoPAFAT; lysophosphatidylcholine acyltransferase 2 (EC:2.3.1.51 2.3.1.23 2.3.1.67); K13510 lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565)	[I]	Lipid transport and metabolism	EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; Acyltransferase;; EF hand	Lysophosphatidylcholine acyltransferase 2 GN=LPCAT2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: lysophosphatidylcholine acyltransferase 2 [Chrysochloris asiatica]
ENSG00000087258(GNAO1)	--	0.1456214	15	0.090390244	4	0.146696932	7	0.112512758	4	0.140255636	12	0.198326444	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04534|0|tup:102483059|GNAO1; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O; K04534 guanine nucleotide-binding protein G(o) subunit alpha (A)"	Rap1 signaling pathway (ko04015);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Guanine nucleotide-binding protein G(o) subunit alpha GN=GNAO1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: guanine nucleotide-binding protein G(o) subunit alpha isoform X2 [Elephantulus edwardii] 
ENSG00000087263(OGFOD1)	--	18.07834	1134	19.233011	1176	19.512812	1200	24.02725	1410	20.04895979	1304	18.21656001	1165	0.923772348	0.283097735	normal	0.975305618	0.127473532	normal	0.980612292	-0.050930748	normal	0.573391336	0.122517745	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706);; Molecular Function: L-ascorbic acid binding (GO:0031418);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	[B]	Chromatin structure and dynamics	Oxoglutarate and iron-dependent oxygenase degradation C-term;; 2OG-Fe(II) oxygenase superfamily	Prolyl 3-hydroxylase OGFOD1 GN=OGFOD1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1 [Tupaia chinensis]
ENSG00000087266(SH3BP2)	--	5.900319266	754	4.325006692	618	6.094991271	603	5.169611267	502	3.453070552	428	4.052651064	471	0.06243498	-0.61615899	normal	0.233112597	-0.549796176	normal	0.806547922	-0.36368762	normal	0.004016012	-0.517027722	normal	--	--	--	"K07984|0|hsa:6452|SH3BP2, 3BP-2, 3BP2, CRBM, CRPM; SH3-domain binding protein 2; K07984 SH3-domain binding protein 2 (A)"	Natural killer cell mediated cytotoxicity (ko04650)	--	--	PH domain;; SH2 domain	SH3 domain-binding protein 2 GN=SH3BP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SH3 domain-binding protein 2 [Galeopterus variegatus]
ENSG00000087269(NOP14)	--	14.16679001	1109	15.301512	1221	14.30644026	1166	16.967558	1365	19.04363702	1480	16.93560163	1324	0.93305105	0.268473586	normal	0.943467752	0.255819256	normal	0.968497206	0.174830968	normal	0.194704704	0.232751361	normal	--	--	Cellular Component: small-subunit processome (GO:0032040);; 	"K14766|0|hsa:8602|NOP14, C4orf9, NOL14, RES425, UTP2; NOP14 nucleolar protein; K14766 nucleolar protein 14 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Nop14-like family	Nucleolar protein 14 GN=NOP14 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: nucleolar protein 14 [Galeopterus variegatus]
ENSG00000087274(ADD1)	--	29.94238582	2450	28.94163393	2335	28.62247694	2348	35.50967601	2856	36.75835813	2949	29.98417232	2453	0.97792877	0.190271374	normal	0.927171884	0.315194709	normal	0.987773041	0.054788857	normal	0.304938973	0.189681388	normal	[G]	Carbohydrate transport and metabolism	--	K18622|0|cjc:100401343|ADD1; adducin 1 (alpha); K18622 adducin (A)	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Class II Aldolase and Adducin N-terminal domain	Alpha-adducin GN=ADD1 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: alpha-adducin isoform X4 [Tupaia chinensis]
ENSG00000087299(L2HGDH)	--	13.210093	670	12.7673316	684	11.217695	640	11.064764	601	12.58995301	499	13.638188	581	0.954486913	-0.187174866	normal	0.485205587	-0.475147591	normal	0.96293742	-0.147459323	normal	0.193984134	-0.267825083	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00109|0|hsa:79944|L2HGDH, C14orf160; L-2-hydroxyglutarate dehydrogenase (EC:1.1.99.2); K00109 2-hydroxyglutarate dehydrogenase [EC:1.1.99.2] (A)"	Butanoate metabolism (ko00650)	[S]	Function unknown	FAD dependent oxidoreductase;; FAD binding domain	"L-2-hydroxyglutarate dehydrogenase, mitochondrial (Precursor) GN=L2HGDH OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: L-2-hydroxyglutarate dehydrogenase, mitochondrial [Galeopterus variegatus]"
ENSG00000087301(TXNDC16)	--	1.833169102	138	1.680429	126	1.165777787	86	1.07096383	81	1.124868278	84	1.67322561	127	0.176591959	-0.787914094	normal	0.653355846	-0.597542663	normal	0.74768809	0.546177783	normal	0.588971159	-0.28191383	normal	--	--	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin-like domain;; Thioredoxin	Thioredoxin domain-containing protein 16 (Precursor) GN=TXNDC16 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: thioredoxin domain-containing protein 16 [Lipotes vexillifer]
ENSG00000087302(C14orf166)	--	54.43895514	1683	62.172907	1663	63.7549508	1666	77.756817	2167	66.5862498	1998	68.109614	1870	0.890142923	0.333562761	normal	0.956927635	0.243139904	normal	0.97686003	0.158222796	normal	0.151594332	0.246321543	normal	--	--	--	"K15433|2.78646e-167|ptr:452904|C14H14orf166; chromosome 14 open reading frame, human C14orf166; K15433 RLL motif containing protein 1 (A)"	--	[R]	General function prediction only	Putative carnitine deficiency-associated protein	UPF0568 protein C14orf166 GN=C14orf166 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0568 protein C14orf166 homolog [Oryctolagus cuniculus]
ENSG00000087303(NID2)	--	2.944639419	285	1.924405346	183	2.18220137	215	4.2312687	414	5.111657	503	9.230121521	910	0.451084041	0.505563712	normal	1.06E-10	1.429865862	up	0	2.065557589	up	0.05538171	1.40063597	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: cell-matrix adhesion (GO:0007160);; 	"K06826|0|hsa:22795|NID2, NID-2; nidogen 2 (osteonidogen); K06826 nidogen (entactin) (A)"	--	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	G2F domain;; Low-density lipoprotein receptor repeat class B;; Nidogen-like;; EGF domain;; Thyroglobulin type-1 repeat;; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; EGF-like domain	Nidogen-2 (Precursor) GN=NID2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: nidogen-2 [Trichechus manatus latirostris]
ENSG00000087338(GMCL1)	--	11.50141778	702	12.22798	755	11.49236682	696	10.22877851	633	8.206596242	501	10.3159331	631	0.957148438	-0.179683394	normal	0.077488602	-0.611577541	normal	0.963673849	-0.149397667	normal	0.113635795	-0.308082457	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10485|0|hsa:64395|GMCL1, BTBD13, GCL, GCL1, SPATA29; germ cell-less, spermatogenesis associated 1; K10485 BTB/POZ domain-containing protein 13 (germ cell-less protein-like 1) (A)"	--	[R]	General function prediction only	BTB/POZ domain;; BTB And C-terminal Kelch	Germ cell-less protein-like 1 GN=GMCL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: germ cell-less protein-like 1 [Ceratotherium simum simum]
ENSG00000087365(SF3B2)	--	72.43677093	4774	76.5730006	4895	74.88325818	4996	73.3856575	4862	77.13637537	4971	68.32616916	4443	0.993237923	-0.004479508	normal	0.993128612	0.00080044	normal	0.986784448	-0.177473776	normal	0.817401183	-0.06015165	normal	[A]	RNA processing and modification	Cellular Component: nucleus (GO:0005634);; 	"K12829|0|hsa:10992|SF3B2, Cus1, SAP145, SF3B145, SF3b1, SF3b150; splicing factor 3b, subunit 2, 145kDa; K12829 splicing factor 3B subunit 2 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Domain of unknown function (DUF382);; PSP;; SAP domain	Splicing factor 3B subunit 2 GN=SF3B2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: splicing factor 3B subunit 2 [Galeopterus variegatus]
ENSG00000087448(KLHL42)	--	12.79383035	1323	13.47050447	1413	13.559702	1251	12.13593001	1266	13.14464499	1346	14.158791	1421	0.979310263	-0.094256005	normal	0.979917406	-0.091409362	normal	0.969584011	0.175334328	normal	0.990301572	-0.004453341	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain"	Kelch-like protein 42 GN=KLHL42 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: kelch-like protein 42 [Pteropus alecto] 
ENSG00000087460(GNAS)	--	273.285621	9839	297.1903263	10758	260.9329016	9540	266.8969679	9605	278.0081337	9969	297.8617132	10772	0.995824545	-0.065547982	normal	0.994614463	-0.131296574	normal	0.993308864	0.166908608	normal	0.976471761	-0.01102666	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	K04632|0|ptr:469986|GNAS; guanine nucleotide-binding protein G(s) subunit alpha; K04632 guanine nucleotide-binding protein G(s) subunit alpha (A)	Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Vasopressin-regulated water reabsorption (ko04962);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Chagas disease (American trypanosomiasis) (ko05142);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	G-protein alpha subunit;; ADP-ribosylation factor family	Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas GN=GNAS OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_003573 [Ailuropoda melanoleuca]
ENSG00000087470(DNM1L)	--	30.19241404	2054	28.780104	2048	29.76615424	2086	33.87250325	2452	36.35386227	2557	29.01154704	2142	0.967512003	0.224536659	normal	0.934549267	0.298612202	normal	0.987164079	0.029906484	normal	0.313164772	0.187175085	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K17065|0|bacu:103015652|DNM1L; dynamin 1-like; K17065 dynamin 1-like protein [EC:3.6.5.5] (A)	TNF signaling pathway (ko04668)	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Dynamin central region;; Dynamin family;; Dynamin GTPase effector domain;; 50S ribosome-binding GTPase	Dynamin-1-like protein GN=DNM1L OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: dynamin-1-like protein isoform X1 [Orycteropus afer afer]
ENSG00000087494(PTHLH)	--	1.857989	45	1.523625465	34	2.238896759	58	10.21071226	251	12.14931874	304	5.038895316	128	0	2.409828399	up	0	3.083922871	up	0.005437496	1.113691806	up	0.000967791	2.295899707	up	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Parathyroid hormone family	Osteostatin (Precursor) GN=PTHLH OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: parathyroid hormone-related protein isoform X1 [Loxodonta africana] 
ENSG00000087502(ERGIC2)	--	23.87282967	1037	23.17548701	1114	21.9513075	997	22.62470978	1118	20.94922261	980	20.98001086	975	0.978133792	0.077561345	normal	0.95731582	-0.206023698	normal	0.978844811	-0.040420726	normal	0.835366533	-0.056580561	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endoplasmic reticulum vesicle transporter;; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)	Endoplasmic reticulum-Golgi intermediate compartment protein 2 GN=ERGIC2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: ERGIC and golgi 2 [Chrysochloris asiatica]
ENSG00000087510(TFAP2C)	--	10.555065	522	11.424684	565	9.562482299	475	4.207550791	209	3.748564571	186	4.16941709	208	5.52E-10	-1.344894359	down	3.87E-14	-1.616433658	down	1.36E-07	-1.193726915	down	7.83E-14	-1.394672788	down	--	--	--	K09177|0|ptr:747174|TFAP2C; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); K09177 transcription factor AP-2 gamma (A)	--	[K]	Transcription	Transcription factor AP-2	Transcription factor AP-2 gamma GN=TFAP2C OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor AP-2 gamma isoform X1 [Leptonychotes weddellii]
ENSG00000087586(AURKA)	--	60.21109845	2024	56.7037526	1813	58.9906276	1973	58.65234842	1960	55.1238612	1994	50.07890537	1706	0.985216426	-0.077128397	normal	0.982038266	0.115767825	normal	0.965330988	-0.21788498	normal	0.815579992	-0.059216387	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K11481|0|hsa:6790|AURKA, AIK, ARK1, AURA, AURORA2, BTAK, PPP1R47, STK15, STK6, STK7; aurora kinase A (EC:2.7.11.1); K11481 aurora kinase A [EC:2.7.11.1] (A)"	Oocyte meiosis (ko04114)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Aurora kinase A OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: aurora kinase A [Ursus maritimus] 
ENSG00000087589(CASS4)	--	0	0	0	0	0.01919364	0	0.019419203	1	0	0	0.096936017	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Serine rich protein interaction domain;; Domain of unknown function (DUF3513);; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Cas scaffolding protein family member 4 GN=CASS4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cas scaffolding protein family member 4 [Galeopterus variegatus]
ENSG00000087842(PIR)	--	38.32905	867	38.93904	900	38.23052	877	18.8869	436	22.05894	499	25.13941	581	1.34E-06	-1.019933997	down	0.000150097	-0.870317882	normal	0.074967681	-0.601047524	normal	1.61E-07	-0.822790916	normal	[R]	General function prediction only	--	K06911|0|hsa:8544|PIR; pirin (iron-binding nuclear protein) (EC:1.13.11.24); K06911 (A)	--	--	--	Pirin C-terminal cupin domain;; Pirin	Pirin GN=PIR OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pirin isoform X1 [Ailuropoda melanoleuca] 
ENSG00000087884(AAMDC)	--	16.77500379	92	12.497057	74	14.65411506	83	19.565444	116	23.76253912	133	19.006816	109	0.941769024	0.299130042	normal	0.168355612	0.811863067	normal	0.91906512	0.378813238	normal	0.211860504	0.502581055	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF498/DUF598)	Mth938 domain-containing protein GN=AAMDC OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mth938 domain-containing protein [Galeopterus variegatus] 
ENSG00000087903(RFX2)	--	2.6784617	178	2.989128896	190	2.273357928	173	2.056016296	96	2.370397113	94	1.919603874	95	0.01545136	-0.910720715	normal	0.002086749	-1.024851032	down	0.035708514	-0.862734634	normal	0.001418143	-0.94601439	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09173|0|hsa:5990|RFX2; regulatory factor X, 2 (influences HLA class II expression); K09173 regulatory factor X 1/2/3 (A)"	--	[K]	Transcription	RFX1 transcription activation region;; RFX DNA-binding domain	DNA-binding protein RFX2 GN=RFX2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: DNA-binding protein RFX2 isoform X1 [Canis lupus familiaris] 
ENSG00000087995(METTL2A)	--	11.18330152	607	10.83596108	584	10.83452909	577	11.901859	676	12.38914929	679	10.568056	575	0.966994493	0.124196493	normal	0.951660049	0.195546683	normal	0.973240557	-0.013265975	normal	0.695101039	0.104811638	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family	Methyltransferase-like protein 2A GN=METTL2A OS=Homo sapiens (Human) PE=1 SV=5	R	General function prediction only	PREDICTED: methyltransferase-like protein 2B [Galeopterus variegatus]
ENSG00000088002(SULT2B1)	--	16.37872038	294	11.34454168	201	11.89787411	219	1.999170021	33	4.615997	90	4.572531953	72	0	-3.127209737	down	0.000122961	-1.167141575	down	7.15E-09	-1.592979442	down	3.31E-07	-1.891647907	down	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K01015|0|pps:100993458|SULT2B1; sulfotransferase family, cytosolic, 2B, member 1; K01015 alcohol sulfotransferase [EC:2.8.2.2] (A)"	Steroid hormone biosynthesis (ko00140)	[R]	General function prediction only	Sulfotransferase domain	Sulfotransferase family cytosolic 2B member 1 GN=SULT2B1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sulfotransferase family cytosolic 2B member 1 [Galeopterus variegatus]
ENSG00000088035(ALG6)	--	8.474948257	216	6.890801851	190	8.299307516	215	9.285759871	216	8.815468389	213	9.089251726	214	0.966616117	-0.030614501	normal	0.957399128	0.142356894	normal	0.96690718	-0.01491217	normal	0.959760504	0.029137858	normal	--	--	"Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K03848|0|nle:100595734|ALG6; asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); K03848 alpha-1,3-glucosyltransferase [EC:2.4.1.267] (A)"	N-Glycan biosynthesis (ko00510)	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	"ALG6, ALG8 glycosyltransferase family"	"Dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase GN=ALG6 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase [Canis lupus familiaris]"
ENSG00000088038(CNOT3)	--	23.05051566	1460	22.7151648	1477	23.43655335	1558	18.92393252	1234	22.189737	1432	22.36578427	1532	0.932556959	-0.273145119	normal	0.981942147	-0.065996261	normal	0.984064801	-0.032538527	normal	0.578745538	-0.119031023	normal	[K]	Transcription	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K12580|0|pps:100979456|CNOT3; CCR4-NOT transcription complex, subunit 3; K12580 CCR4-NOT transcription complex subunit 3 (A)"	RNA degradation (ko03018)	[K]	Transcription	"Not1 N-terminal domain, CCR4-Not complex component;; NOT2 / NOT3 / NOT5 family"	CCR4-NOT transcription complex subunit 3 GN=CNOT3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 3 isoform X4 [Galeopterus variegatus]
ENSG00000088053(GP6)	--	0.10174509	4	0.286768231	11	0.128270227	4	0.052597835	2	0.076486106	2	0.104098973	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06264|0|hsa:51206|GP6, BDPLT11, GPIV, GPVI; glycoprotein VI (platelet); K06264 platelet glycoprotein VI (A)"	ECM-receptor interaction (ko04512);; Platelet activation (ko04611)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	Platelet glycoprotein VI (Precursor) GN=GP6 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: platelet glycoprotein VI isoform X1 [Equus caballus] 
ENSG00000088179(PTPN4)	--	6.876712001	750	6.079758355	781	4.8099388	684	2.8440628	416	2.7649829	428	3.17062091	469	0.00013307	-0.878684905	normal	0.000131701	-0.886782131	normal	0.201194652	-0.551219097	normal	3.03E-06	-0.775477211	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18037|0|hsa:5775|PTPN4, MEG, PTPMEG, PTPMEG1; protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) (EC:3.1.3.48); K18037 tyrosine-protein phosphatase non-receptor type 4 [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase;; FERM C-terminal PH-like domain;; FERM central domain;; FERM N-terminal domain;; PDZ domain (Also known as DHR or GLGF);; FERM adjacent (FA)	Tyrosine-protein phosphatase non-receptor type 4 GN=PTPN4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 4 [Panthera tigris altaica]
ENSG00000088205(DDX18)	--	32.447452	2181	38.128481	2618	36.474113	2447	26.778662	1853	25.50833765	1710	23.652602	1628	0.948949546	-0.265755761	normal	0.031644653	-0.635437486	normal	0.064579441	-0.595750239	normal	0.00052242	-0.502765815	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K13179|0|hsa:8886|DDX18, MrDb; DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 (EC:3.6.4.13); K13179 ATP-dependent RNA helicase DDX18/HAS1 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Domain of unknown function (DUF4217);; Helicase conserved C-terminal domain	ATP-dependent RNA helicase DDX18 GN=DDX18 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX18 [Galeopterus variegatus]
ENSG00000088247(KHSRP)	--	67.99443403	4053	66.40456674	4176	75.881386	4509	77.55424951	4723	78.93785982	4794	71.6926624	4408	0.984703321	0.189814393	normal	0.98609408	0.177621568	normal	0.992533367	-0.040960833	normal	0.63203599	0.107331315	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K13210|0|ssc:100516780|KHSRP; KH-type splicing regulatory protein; K13210 far upstream element-binding protein (A)	--	[A]	RNA processing and modification	KH domain;; KH domain;; KH domain;; Domain of unknown function (DUF1897);; KH domain	Far upstream element-binding protein 2 GN=KHSRP OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: far upstream element-binding protein 2 [Orcinus orca]
ENSG00000088256(GNA11)	--	16.9880149	1363	15.09923699	1225	17.45884854	1471	18.9433214	1547	19.56194053	1432	17.86334659	1429	0.974843623	0.151694795	normal	0.962685007	0.203590536	normal	0.982935814	-0.050030585	normal	0.667554639	0.097806485	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04635|0|hsa:2767|GNA11, FBH, FBH2, FHH2, GNA-11, HHC2, HYPOC2; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); K04635 guanine nucleotide-binding protein subunit alpha-11 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Cholinergic synapse (ko04725);; Long-term depression (ko04730);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Chagas disease (American trypanosomiasis) (ko05142);; Amoebiasis (ko05146);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	G-protein alpha subunit;; ADP-ribosylation factor family	Guanine nucleotide-binding protein subunit alpha-11 GN=GNA11 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit alpha-11 [Monodelphis domestica]
ENSG00000088280(ASAP3)	--	4.460293388	369	3.349366987	287	4.644593006	316	2.819408818	237	4.030809553	290	2.490153976	197	0.07180158	-0.666074715	normal	0.966641475	-0.006390894	normal	0.074596791	-0.685824225	normal	0.067927518	-0.446520286	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	"K12488|0|ptr:456617|ASAP3, DDEFL1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 3; K12488 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein (A)"	Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; PH domain;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	"Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 GN=ASAP3 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 isoform X1 [Lipotes vexillifer]"
ENSG00000088298(EDEM2)	--	48.09044	1720	44.28148	1599	52.219192	1890	29.48946	1057	29.460312	1046	27.71519	991	0.002230321	-0.732421893	normal	0.03417463	-0.632967553	normal	3.72E-06	-0.93866509	normal	2.82E-08	-0.772650521	normal	--	--	"Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: membrane (GO:0016020);; "	"K10085|0|ptr:458197|EDEM2, C20orf31; ER degradation enhancer, mannosidase alpha-like 2; K10085 ER degradation enhancer, mannosidase alpha-like 2 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 47	ER degradation-enhancing alpha-mannosidase-like protein 2 (Precursor) GN=EDEM2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: ER degradation-enhancing alpha-mannosidase-like protein 2 isoform X1 [Bos taurus]
ENSG00000088305(DNMT3B)	--	4.787486076	570	5.083770942	649	4.198890034	528	3.58685149	449	3.959604011	480	4.363788513	540	0.787339834	-0.373939909	normal	0.562639562	-0.455371698	normal	0.97226045	0.024061887	normal	0.207352883	-0.270955694	normal	--	--	--	K17399|0|ggo:101154595|DNMT3B; DNA (cytosine-5)-methyltransferase 3B isoform 1; K17399 DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37] (A)	Cysteine and methionine metabolism (ko00270);; MicroRNAs in cancer (ko05206)	--	--	PWWP domain;; C-5 cytosine-specific DNA methylase	DNA (cytosine-5)-methyltransferase 3B GN=DNMT3B OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA (cytosine-5)-methyltransferase 3B isoform 1 [Ceratotherium simum simum]
ENSG00000088325(TPX2)	--	55.64617	4515	48.8612272	3924	57.707424	4603	57.502255	4649	52.318749	4216	47.659152	3859	0.992946447	0.011358366	normal	0.990869205	0.082092741	normal	0.969331879	-0.262544505	normal	0.826877892	-0.057184703	normal	--	--	--	"K16812|0|hsa:22974|TPX2, C20orf1, C20orf2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA519, HCTP4, REPP86, p100; TPX2, microtubule-associated; K16812 targeting protein for Xklp2 (A)"	--	--	--	Cell cycle regulated microtubule associated protein;; Aurora-A binding;; Targeting protein for Xklp2 (TPX2);; Putative binding domain	Targeting protein for Xklp2 GN=TPX2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	hypothetical protein PANDA_006779 [Ailuropoda melanoleuca]
ENSG00000088356(PDRG1)	--	10.8803575	412	11.9500584	462	10.8976	418	17.019333	652	17.217934	648	13.4591429	512	0.05869467	0.629514422	normal	0.529339124	0.465382571	normal	0.905699888	0.283421442	normal	0.01374344	0.466035001	normal	--	--	Biological Process: protein folding (GO:0006457);; Cellular Component: prefoldin complex (GO:0016272);; Molecular Function: unfolded protein binding (GO:0051082);; 	--	--	--	--	Prefoldin subunit	p53 and DNA damage-regulated protein 1 GN=PDRG1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: p53 and DNA damage-regulated protein 1 [Pteropus alecto] 
ENSG00000088367(EPB41L1)	--	54.77834882	3199	44.56872125	3226	43.8126251	3344	48.2678782	3222	46.16202807	3180	102.5937394	3357	0.990647544	-0.020486958	normal	0.990085162	-0.04212634	normal	0.991006187	-0.002692537	normal	0.940882927	-0.022481556	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: cytoskeleton (GO:0005856);; 	K06107|0|ptr:469929|EPB41L1; erythrocyte membrane protein band 4.1-like 1; K06107 erythrocyte membrane protein band 4.1 (A)	Tight junction (ko04530)	[R]	General function prediction only	4.1 protein C-terminal domain (CTD)	Band 4.1-like protein 1 GN=EPB41L1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: band 4.1-like protein 1 isoform X2 [Equus przewalskii]
ENSG00000088387(DOCK9)	--	7.3569404	1037	6.339219753	875	7.669507129	1071	8.933580004	1160	7.09595073	979	7.179966709	989	0.973548636	0.130693506	normal	0.969376253	0.140369843	normal	0.973674255	-0.123026666	normal	0.867459423	0.046986357	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Dedicator of cytokinesis;; C2 domain in Dock180 and Zizimin proteins;; Domain of unknown function (DUF3398);; PH domain	Dedicator of cytokinesis protein 9 GN=DOCK9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 9 isoform X10 [Galeopterus variegatus]
ENSG00000088448(ANKRD10)	--	22.52301422	1329	24.05589388	1451	20.861746	1311	24.60570851	1501	23.09972616	1393	27.48901994	1637	0.975414415	0.144593254	normal	0.980972664	-0.080193507	normal	0.903776195	0.311772724	normal	0.55303736	0.126286062	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 10 GN=ANKRD10 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 10 [Eptesicus fuscus]
ENSG00000088451(TGDS)	--	5.229027168	150	5.465621	152	5.128997149	144	5.969758435	173	5.828170339	166	4.334168048	123	0.956308832	0.173323214	normal	0.96254168	0.104688483	normal	0.948853716	-0.233050864	normal	0.967100796	0.028643304	normal	[M]	Cell wall/membrane/envelope biogenesis	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K01710|0|hsa:23483|TGDS, SDR2E1, TDPGD; TDP-glucose 4,6-dehydratase (EC:4.2.1.46); K01710 dTDP-glucose 4,6-dehydratase [EC:4.2.1.46] (A)"	--	[G]	Carbohydrate transport and metabolism	NAD dependent epimerase/dehydratase family;; 3-beta hydroxysteroid dehydrogenase/isomerase family;; Polysaccharide biosynthesis protein;; RmlD substrate binding domain;; Male sterility protein;; NADH(P)-binding	"dTDP-D-glucose 4,6-dehydratase GN=TGDS OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: dTDP-D-glucose 4,6-dehydratase [Vicugna pacos]"
ENSG00000088538(DOCK3)	--	2.116685166	346	1.790612256	284	1.901633432	313	1.087388125	177	1.379819374	218	1.94564115	307	0.000144651	-0.991576984	normal	0.796729719	-0.400547141	normal	0.967494127	-0.036039618	normal	0.160135946	-0.445295767	normal	--	--	--	"K05727|0|hsa:1795|DOCK3, MOCA, PBP; dedicator of cytokinesis 3; K05727 dedicator of cytokinesis protein 3 (A)"	--	[T]	Signal transduction mechanisms	Dedicator of cytokinesis;; C2 domain in Dock180 and Zizimin proteins;; Variant SH3 domain	Dedicator of cytokinesis protein 3 GN=DOCK3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 3 isoform X10 [Oryctolagus cuniculus]
ENSG00000088543(C3orf18)	--	5.170883916	250	3.355821056	155	3.07639	171	2.20804034	114	3.4385965	156	2.446430383	133	2.92E-05	-1.152952307	down	0.966369893	-0.012031734	normal	0.887041208	-0.367169645	normal	0.187034909	-0.536110811	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C3orf18 GN=C3orf18 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C3orf18 homolog [Felis catus] 
ENSG00000088682(COQ9)	--	25.4639721	797	24.723584	819	28.86567515	873	26.891608	878	27.97496531	878	30.985781	1002	0.972334716	0.108609428	normal	0.97457998	0.078790403	normal	0.960005554	0.190229696	normal	0.581237946	0.127384821	normal	[S]	Function unknown	--	"K18587|0|hsa:57017|COQ9, C16orf49, COQ10D5; coenzyme Q9; K18587 ubiquinone biosynthesis protein COQ9 (A)"	--	[S]	Function unknown	COQ9	"Ubiquinone biosynthesis protein COQ9, mitochondrial (Precursor) GN=COQ9 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: ubiquinone biosynthesis protein COQ9, mitochondrial [Balaenoptera acutorostrata scammoni]"
ENSG00000088726(TMEM40)	--	0	0	0	0	0	0	0.235734529	6	0.25584994	6	0.471648893	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 40 GN=TMEM40 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 40 [Galeopterus variegatus]
ENSG00000088727(KIF9)	--	6.825068907	80	4.4696965	60	7.04314786	80	6.1508706	86	5.153064535	62	3.876824221	53	0.97205056	0.072167509	normal	0.975107321	0.025253018	normal	0.837292711	-0.588535601	normal	0.824780737	-0.152752798	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10397|0|hsa:64147|KIF9; kinesin family member 9; K10397 kinesin family member 6/9 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF9 GN=KIF9 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF9 isoform 1 [Ceratotherium simum simum]
ENSG00000088756(ARHGAP28)	--	0.196628406	5	0.236878828	10	0.080773153	3	0	0	0.173503791	5	0.044256571	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain	Rho GTPase-activating protein 28 GN=ARHGAP28 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 28 isoform X2 [Canis lupus familiaris]
ENSG00000088766(CRLS1)	--	24.537303	794	27.0864118	897	22.183042	759	29.543471	935	31.109116	983	31.067687	1051	0.954170854	0.204629904	normal	0.973263325	0.110478908	normal	0.501347306	0.460516371	normal	0.16872218	0.256147837	normal	[I]	Lipid transport and metabolism	"Biological Process: phospholipid biosynthetic process (GO:0008654);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, for other substituted phosphate groups (GO:0016780);; "	K08744|8.62596e-154|ptr:458087|CRLS1; cardiolipin synthase 1; K08744 cardiolipin synthase [EC:2.7.8.-] (A)	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	CDP-alcohol phosphatidyltransferase	Cardiolipin synthase GN=CRLS1 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: cardiolipin synthase [Camelus bactrianus]
ENSG00000088808(PPP1R13B)	--	2.295472641	241	2.107706383	228	1.73172621	193	2.206003751	243	2.83919756	278	1.950670604	217	0.96694411	-0.018789803	normal	0.92346794	0.263042305	normal	0.956152418	0.159622595	normal	0.721058147	0.135055018	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17554|0|hsa:23368|PPP1R13B, ASPP1, p53BP2-like, p85; protein phosphatase 1, regulatory subunit 13B; K17554 apoptosis-stimulating of p53 protein 1 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; SH3 domain;; Ankyrin repeat;; Variant SH3 domain;; Ankyrin repeats (many copies);; Variant SH3 domain	Apoptosis-stimulating of p53 protein 1 GN=PPP1R13B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: apoptosis-stimulating of p53 protein 1 [Equus caballus]
ENSG00000088812(ATRN)	--	24.65528	3242	24.49339	3181	24.625701	3228	28.6619	3739	27.06349	3435	26.48940471	3546	0.983775293	0.174858907	normal	0.98905582	0.089362281	normal	0.987601609	0.127203638	normal	0.534127754	0.130189207	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	"Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Lectin C-type domain;; Galactose oxidase, central domain;; Plexin repeat;; Kelch motif;; Kelch motif;; CUB domain"	Attractin (Precursor) GN=ATRN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: attractin isoform X1 [Pteropus alecto] 
ENSG00000088826(SMOX)	--	115.2976583	5099	75.6835362	3421	83.93642021	3822	56.59022551	2521	61.89845479	2718	56.68314587	2533	2.81E-08	-1.046592096	down	0.894561541	-0.353123643	normal	0.063153279	-0.601477681	normal	0.013180765	-0.688457038	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K12259|0|hsa:54498|SMOX, C20orf16, PAO, PAO-1, PAO1, PAOH, PAOH1, SMO; spermine oxidase (EC:1.5.3.16); K12259 spermine oxidase [EC:1.5.3.16 1.5.3.-] (A)"	Arginine and proline metabolism (ko00330);; beta-Alanine metabolism (ko00410)	[H]	Coenzyme transport and metabolism	Flavin containing amine oxidoreductase;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; FAD binding domain	Spermine oxidase GN=SMOX OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: spermine oxidase isoform X2 [Galeopterus variegatus]
ENSG00000088827(SIGLEC1)	--	0.012076865	1	0	0	0	0	0	0	0	0	0.007331026	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06548|0|hsa:6614|SIGLEC1, CD169, SIGLEC-1, SN, dJ1009E24.1; sialic acid binding Ig-like lectin 1, sialoadhesin; K06548 sialoadhesin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[RP]	General function prediction only;; Inorganic ion transport and metabolism	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain;; Penicillin-Binding Protein C-terminus Family;; Alphaherpesvirus glycoprotein E	Sialoadhesin (Precursor) GN=SIGLEC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: sialoadhesin [Galeopterus variegatus]
ENSG00000088832(FKBP1A)	--	262.893898	5791	260.0697	5825	258.8677972	5730	346.288285	7782	311.524484	6835	309.2701652	6847	0.878328344	0.395405442	normal	0.986334442	0.209206547	normal	0.980158778	0.248585339	normal	0.104818587	0.285673272	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09568|6.51733e-42|mcc:698165|FK506 binding protein 1A, 12kDa pseudogene; K09568 FK506-binding protein 1 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase	Peptidyl-prolyl cis-trans isomerase FKBP1A GN=FKBP1A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP1A isoform X2 [Chrysochloris asiatica]
ENSG00000088833(NSFL1C)	--	34.651682	2098	33.955307	1963	36.526669	2052	37.552837	2099	35.395944	2173	34.642692	1922	0.987087424	-0.03012272	normal	0.982266109	0.125109809	normal	0.983814887	-0.102635664	normal	0.998020245	-0.002383755	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K14012|0|hsa:55968|NSFL1C, P47, UBX1, UBXD10, UBXN2C, dJ776F14.1; NSFL1 (p97) cofactor (p47); K14012 UBX domain-containing protein 1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[Y]	Nuclear structure	SEP domain;; UBX domain;; UBA-like domain	NSFL1 cofactor p47 GN=NSFL1C OS=Homo sapiens (Human) PE=1 SV=2	Y	Nuclear structure	PREDICTED: NSFL1 (p97) cofactor (p47) isoform X1 [Sus scrofa]
ENSG00000088836(SLC4A11)	--	4.86161627	269	3.1364036	173	3.943630904	218	2.680699084	145	3.733557018	209	2.8508472	160	0.002286357	-0.915146362	normal	0.934541032	0.249319062	normal	0.755509257	-0.450881834	normal	0.318871795	-0.381383482	normal	--	--	Biological Process: anion transport (GO:0006820);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13862|0|pps:100973783|SLC4A11; solute carrier family 4, sodium borate transporter, member 11; K13862 solute carrier family 4 (sodium borate transporter), member 11 (A)"	--	[P]	Inorganic ion transport and metabolism	"HCO3- transporter family;; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2"	Sodium bicarbonate transporter-like protein 11 GN=SLC4A11 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium bicarbonate transporter-like protein 11 [Galeopterus variegatus]
ENSG00000088854(C20orf194)	--	3.91736	506	3.830262	492	3.68468	476	4.42136	570	4.073943	516	4.33267	555	0.962432508	0.14058991	normal	0.970141955	0.047144689	normal	0.944097163	0.212608637	normal	0.619013198	0.13345025	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C20orf194 GN=C20orf194 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C20orf194 homolog isoform 1 [Odobenus rosmarus divergens]
ENSG00000088876(ZNF343)	--	7.316501094	403	5.227326932	439	6.794133722	408	5.685677796	411	7.462636482	392	6.097997121	475	0.969833553	-0.002464405	normal	0.950209813	-0.184122184	normal	0.943606887	0.2103437	normal	0.984925516	0.011100612	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:79175|ZNF343, dJ734P14.5; zinc finger protein 343; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; C2H2-type zinc finger;; Putative binding domain"	Zinc finger protein 343 GN=ZNF343 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 343-like isoform X1 [Galeopterus variegatus] 
ENSG00000088881(EBF4)	--	5.745098227	229	3.638864063	150	4.225620976	176	1.52690115	69	2.823044101	124	1.434543875	69	1.08E-10	-1.738947339	down	0.929726812	-0.292796733	normal	1.33E-05	-1.340139501	down	0.004620462	-1.103833092	down	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09103|0|ggo:101143742|EBF4; transcription factor COE4; K09103 early B-cell factor (A)	--	[K]	Transcription	IPT/TIG domain	Transcription factor COE4 GN=EBF4 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: transcription factor COE4 [Pteropus alecto]
ENSG00000088882(CPXM1)	--	0	0	0	0	0	0	0	0	0	0	0.0205891	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	K08638|0|ggo:101144115|CPXM1; probable carboxypeptidase X1 isoform 1; K08638 carboxypeptidase X1 [EC:3.4.17.-] (A)	--	[R]	General function prediction only	Zinc carboxypeptidase;; F5/8 type C domain;; Carboxypeptidase regulatory-like domain	Probable carboxypeptidase X1 (Precursor) GN=CPXM1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: probable carboxypeptidase X1 [Galeopterus variegatus]
ENSG00000088888(MAVS)	--	20.39482	4639	22.16625	5099	22.68547	5179	26.97005	6116	25.62355	5761	23.18767	5288	0.90446426	0.367835911	normal	0.989680837	0.154635195	normal	0.993581264	0.021750891	normal	0.356948612	0.180982919	normal	--	--	--	K12648|0|pps:100979730|MAVS; mitochondrial antiviral signaling protein; K12648 mitochondrial antiviral-signaling protein (A)	RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	--	Mitochondrial antiviral-signaling protein GN=MAVS OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitochondrial antiviral-signaling protein [Galeopterus variegatus] 
ENSG00000088899(LZTS3)	--	6.276425833	549	4.538086418	417	5.403827875	492	4.767447554	422	5.293496338	476	5.169988964	473	0.708386786	-0.409085244	normal	0.954436075	0.168913958	normal	0.969587277	-0.064906085	normal	0.707950128	-0.109484589	normal	--	--	--	--	--	--	--	Fez1	Leucine zipper putative tumor suppressor 3 GN=LZTS3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine zipper putative tumor suppressor 3-like isoformX1 [Equus caballus] 
ENSG00000088930(XRN2)	--	61.47235524	4052	64.60966156	4226	60.2659373	3958	69.487364	4549	72.90819735	4720	64.63519279	4239	0.989161636	0.136034298	normal	0.989137837	0.138020783	normal	0.990878349	0.090627447	normal	0.575552504	0.121234791	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: exonuclease activity (GO:0004527);; 	K12619|0|hsa:22803|XRN2; 5'-3' exoribonuclease 2 (EC:3.1.13.-); K12619 5'-3' exoribonuclease 2 [EC:3.1.13.-] (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA degradation (ko03018)	[LA]	"Replication, recombination and repair;; RNA processing and modification"	XRN 5'-3' exonuclease N-terminus	5'-3' exoribonuclease 2 GN=XRN2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: 5'-3' exoribonuclease 2 isoform X2 [Mustela putorius furo] 
ENSG00000088970(KIZ)	--	3.715136933	218	3.264206547	180	3.111860737	188	3.345003531	198	4.32068941	253	3.936099421	244	0.954594493	-0.168413832	normal	0.69546977	0.466394445	normal	0.858317912	0.365271014	normal	0.516550292	0.225543094	normal	--	--	--	"K16539|0|ptr:458130|KIZ, NCRNA00153, PLK1S1; kizuna centrosomal protein; K16539 centrosomal protein kizuna (A)"	--	--	--	--	Centrosomal protein kizuna GN=KIZ OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein kizuna isoform X1 [Equus caballus]
ENSG00000088986(DYNLL1)	--	291.2114787	2717	247.5734946	2365	287.451379	2738	322.9226223	3084	290.3214815	2723	269.9387485	2546	0.984050782	0.151875289	normal	0.978499823	0.181821819	normal	0.986124832	-0.113116662	normal	0.756761838	0.073497891	normal	--	--	--	"K10418|5.06778e-62|phd:102338635|DYNLL1; dynein, light chain, LC8-type 1; K10418 dynein light chain LC8-type (A)"	Vasopressin-regulated water reabsorption (ko04962)	[Z]	Cytoskeleton	Dynein light chain type 1	"Dynein light chain 1, cytoplasmic GN=DYNLL1 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: dynein light chain 1, cytoplasmic [Pantholops hodgsonii]"
ENSG00000088992(TESC)	--	77.70338	1376	52.7985	968	53.96849	1021	16.576172	295	20.15644	378	20.14651	371	0	-2.246544221	down	4.28E-12	-1.374479738	down	3.49E-14	-1.465026738	down	6.51E-09	-1.709102456	down	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K17612|3.14235e-158|pon:100462515|TESC; tescalcin; K17612 calcineurin B homologous protein 3 (A)	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain	Calcineurin B homologous protein 3 GN=TESC OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: calcineurin B homologous protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000089006(SNX5)	--	86.484462	2839	74.99841542	2555	91.37857814	2851	111.3689622	3801	106.9642251	3634	87.4146284	3062	0.829191903	0.389980961	normal	0.484692397	0.486565947	normal	0.98815662	0.094666339	normal	0.04091353	0.32670641	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17920|0|pps:100968765|SNX5; sorting nexin 5; K17920 sorting nexin-5/6/32 (A)	--	[V]	Defense mechanisms	PX domain;; Vps5 C terminal like;; BAR domain	Sorting nexin-5 GN=SNX5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-5 [Ceratotherium simum simum]
ENSG00000089009(RPL6)	--	921.780211	14489	889.1990969	14206	851.0292252	13584	1098.360339	17804	1116.754108	17615	1026.144605	16393	0.988708216	0.266385598	normal	0.985232013	0.288849867	normal	0.988354123	0.262853418	normal	0.167109206	0.271832947	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02934|1.22153e-160|ptr:452266|RPL6; ribosomal protein L6; K02934 large subunit ribosomal protein L6e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein L6e;; Ribosomal protein L6, N-terminal domain"	60S ribosomal protein L6 GN=RPL6 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L6 [Canis lupus familiaris]
ENSG00000089022(MAPKAPK5)	--	18.9734108	821	17.58235516	870	18.47973244	841	23.56735859	1030	22.02058486	969	20.97385141	975	0.90368206	0.295862767	normal	0.970182766	0.133834199	normal	0.955252889	0.20466289	normal	0.281210195	0.210734593	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K04442|0|mcf:102123012|MAPKAPK5; mitogen-activated protein kinase-activated protein kinase 5; K04442 mitogen-activated protein kinase-activated protein kinase 5 [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	MAP kinase-activated protein kinase 5 GN=MAPKAPK5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: MAP kinase-activated protein kinase 5 isoform X3 [Tupaia chinensis]
ENSG00000089041(P2RX7)	--	0.0848646	9	0.0283872	3	0.187045	19	0	0	0	0	0.00934717	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: purinergic nucleotide receptor activity (GO:0001614);; Molecular Function: extracellular ATP-gated cation channel activity (GO:0004931);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: response to ATP (GO:0033198);; Biological Process: cation transmembrane transport (GO:0098655);; 	"K05220|0|hsa:5027|P2RX7, P2X7; purinergic receptor P2X, ligand-gated ion channel, 7; K05220 P2X purinoceptor 7 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	--	--	ATP P2X receptor	P2X purinoceptor 7 GN=P2RX7 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: P2X purinoceptor 7 [Galeopterus variegatus]
ENSG00000089048(ESF1)	--	14.86639503	1297	19.74621	1425	17.27871	1388	13.590636	1158	13.108173	1119	15.08034	1165	0.963756892	-0.194131932	normal	0.814069437	-0.369734445	normal	0.938866711	-0.260658644	normal	0.106777002	-0.277059999	normal	[S]	Function unknown	Cellular Component: nucleus (GO:0005634);; 	--	--	[S]	Function unknown	NUC153 domain	ESF1 homolog GN=ESF1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ESF1 homolog [Lipotes vexillifer]
ENSG00000089050(RBBP9)	--	15.9421	998	12.74401	790	15.72984	963	15.48869	973	15.13965	947	13.92898	875	0.977636606	-0.067327293	normal	0.940722908	0.239665707	normal	0.968841521	-0.146303091	normal	1	0.001580703	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K07002|1.85095e-127|ptr:458118|RBBP9; retinoblastoma binding protein 9; K07002 (A)	--	--	--	Serine hydrolase;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold	Putative hydrolase RBBP9 GN=RBBP9 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: putative hydrolase RBBP9 [Ursus maritimus]
ENSG00000089053(ANAPC5)	--	47.47770681	2015	41.92877869	1815	45.98891205	1933	59.77240654	2566	62.08568226	2634	49.35824357	2100	0.916302481	0.317693977	normal	0.317589148	0.515500801	normal	0.983389267	0.111172782	normal	0.045327915	0.319406812	normal	--	--	--	K03352|0|ptr:452321|ANAPC5; anaphase promoting complex subunit 5; K03352 anaphase-promoting complex subunit 5 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	Anaphase-promoting complex subunit 5;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Anaphase-promoting complex subunit 5 GN=ANAPC5 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anaphase-promoting complex subunit 5 [Panthera tigris altaica] 
ENSG00000089057(SLC23A2)	--	30.08773445	3607	20.28445199	2431	21.02469723	2504	20.46663549	2419	26.3306423	3137	30.13539102	3505	0.05415948	-0.606902917	normal	0.897873823	0.346219029	normal	0.500101819	0.476644018	normal	0.908434478	0.064801881	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14611|0|ptr:458079|SLC23A2, SLC23A1; solute carrier family 23 (ascorbic acid transporter), member 2; K14611 solute carrier family 23 (nucleobase transporter), member 1/2 (A)"	--	[F]	Nucleotide transport and metabolism	Permease family	Solute carrier family 23 member 2 GN=SLC23A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 23 member 2 [Galeopterus variegatus] 
ENSG00000089060(SLC8B1)	--	4.851873598	267	4.037925204	230	3.781019946	196	4.750088055	238	6.104196296	355	5.703219508	281	0.947730048	-0.195517881	normal	0.208817086	0.601551896	normal	0.552997735	0.508133699	normal	0.366051695	0.313834299	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13754|0|hsa:80024|SLC8B1, NCKX6, NCLX, SLC24A6; solute carrier family 8 (sodium/lithium/calcium exchanger), member B1; K13754 solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium/calcium exchanger protein	"Sodium/potassium/calcium exchanger 6, mitochondrial (Precursor) GN=SLC8B1 OS=Homo sapiens (Human) PE=1 SV=2"	P	Inorganic ion transport and metabolism	"PREDICTED: sodium/potassium/calcium exchanger 6, mitochondrial [Galeopterus variegatus]"
ENSG00000089063(TMEM230)	--	122.0906411	2307	95.24690819	1811	104.3720102	1957	104.0719166	1960	102.4197214	1782	120.829973	2242	0.950545886	-0.265804292	normal	0.984949478	-0.044678156	normal	0.974734874	0.187715459	normal	0.895327936	-0.042645193	normal	--	--	--	--	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF872);; Putative binding domain	Transmembrane protein 230 GN=TMEM230 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 230 [Orycteropus afer afer]
ENSG00000089091(DZANK1)	--	2.19908016	135	1.85595727	133	1.730122	116	1.978443359	111	1.79712447	123	1.59783459	113	0.930837492	-0.309342043	normal	0.962147766	-0.132625839	normal	0.969107946	-0.045492546	normal	0.738229515	-0.167503419	normal	--	--	--	--	--	--	--	Double zinc ribbon;; Chitobiase/beta-hexosaminidase C-terminal domain;; Fn3 associated;; Chitobiase/beta-hexosaminidase C-terminal domain;; Ankyrin repeats (3 copies);; zinc-ribbon domain;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Double zinc ribbon and ankyrin repeat-containing protein 1 GN=DZANK1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: double zinc ribbon and ankyrin repeat-containing protein 1 [Oryctolagus cuniculus] 
ENSG00000089094(KDM2B)	--	8.602243331	771	9.819830866	895	9.783190652	709	9.950373179	910	11.82276736	904	8.98008407	846	0.952586959	0.207921715	normal	0.977809369	-0.006979733	normal	0.935300219	0.246099465	normal	0.530077875	0.141795043	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	"K10276|0|ptr:465184|KDM2B, FBXL10; lysine (K)-specific demethylase 2B; K10276 F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] (A)"	--	[B]	Chromatin structure and dynamics	"CXXC zinc finger domain;; F-box domain;; F-box-like;; Cupin-like domain;; JmjC domain, hydroxylase;; Leucine Rich repeat"	Lysine-specific demethylase 2B GN=KDM2B OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: lysine-specific demethylase 2B [Odobenus rosmarus divergens]
ENSG00000089101(CFAP61)	--	0.796482083	7	0.20864308	7	1.033081	12	0.189635772	3	0.2361	1	0.156296	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cilia- and flagella-associated protein 61 {ECO:0000312|HGNC:HGNC:15872} OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C20orf26 homolog [Equus caballus]
ENSG00000089123(TASP1)	--	5.794349573	165	5.439341966	195	8.427588006	197	8.201565657	295	9.654307825	264	7.365754153	242	0.014061836	0.801761202	normal	0.788742201	0.412876006	normal	0.916726147	0.286532147	normal	0.05750161	0.502455252	normal	[E]	Amino acid transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K08657|0|hsa:55617|TASP1, C20orf13, dJ585I14.2; taspase, threonine aspartase, 1 (EC:3.4.25.-); K08657 taspase, threonine aspartase, 1 [EC:3.4.25.-] (A)"	--	[E]	Amino acid transport and metabolism	Asparaginase	Threonine aspartase subunit beta GN=TASP1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: threonine aspartase 1 [Myotis brandtii] 
ENSG00000089127(OAS1)	--	7.900244922	258	6.453042889	276	5.830952216	250	7.687977001	300	6.628612942	276	8.748432326	319	0.949665487	0.185732764	normal	0.966265387	-0.021309797	normal	0.864335007	0.341503828	normal	0.600233011	0.169857297	normal	--	--	Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K14216|0|hsa:4938|OAS1, IFI-4, OIAS, OIASI; 2'-5'-oligoadenylate synthetase 1, 40/46kDa (EC:2.7.7.84); K14216 2'-5'-oligoadenylate synthetase [EC:2.7.7.84] (A)"	Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	"2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus;; Nucleotidyltransferase domain"	2'-5'-oligoadenylate synthase 1 GN=OAS1 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 2'-5'-oligoadenylate synthase 1-like [Pantholops hodgsonii]
ENSG00000089154(GCN1)	--	32.1874	5915	31.45	5872	33.4019	6222	37.7972	6903	36.9794	6717	37.2856	6819	0.988381184	0.191966862	normal	0.989649259	0.172496942	normal	0.992650394	0.123861582	normal	0.436283249	0.161473216	normal	--	--	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Domain of unknown function (DUF3554);; HEAT repeats;; HEAT repeat;; HEAT-like repeat;; CLASP N terminal;; Vacuolar 14 Fab1-binding region;; Adaptin N terminal region;; non-SMC mitotic condensation complex subunit 1;; Parkin co-regulated protein;; Armadillo/beta-catenin-like repeat	Translational activator GCN1 GN=GCN1L1 OS=Homo sapiens (Human) PE=1 SV=6	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: translational activator GCN1 [Mustela putorius furo] 
ENSG00000089157(RPLP0)	--	1623.316117	32651	1477.197072	29721	1449.963436	29445	1978.961096	40174	2029.795673	40430	1995.69374	40204	0.994155284	0.268291274	normal	0.946926686	0.42249849	normal	0.921134249	0.441005471	normal	0.066647883	0.374621774	normal	[J]	"Translation, ribosomal structure and biogenesis"	Cellular Component: intracellular (GO:0005622);; Biological Process: ribosome biogenesis (GO:0042254);; 	"K02941|0|ptr:452301|RPLP0; ribosomal protein, large, P0; K02941 large subunit ribosomal protein LP0 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L10;; 60s Acidic ribosomal protein	60S acidic ribosomal protein P0 GN=RPLP0 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	"ribosomal protein, large, P0 [Canis lupus familiaris] "
ENSG00000089159(PXN)	--	62.92880992	4426	58.39814173	4071	69.60338418	4814	91.62961394	6384	76.84394305	5328	71.36769214	4841	0.479904574	0.497480434	normal	0.902402328	0.366664924	normal	0.993224635	-0.00022242	normal	0.125308859	0.292653682	normal	--	--	--	K05760|0|pps:100972364|PXN; paxillin; K05760 paxillin (A)	Chemokine signaling pathway (ko04062);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Paxillin family;; LIM domain	Paxillin GN=PXN OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: paxillin isoform X1 [Equus caballus]
ENSG00000089163(SIRT4)	--	0.5780219	9	0.583875829	12	0.865899976	17	0.629888466	13	0.772996717	15	0.930834186	19	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: NAD+ binding (GO:0070403);; 	"K11414|0|hsa:23409|SIRT4, SIR2L4; sirtuin 4; K11414 NAD-dependent deacetylase sirtuin 4 [EC:3.5.1.-] (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	Sir2 family	NAD-dependent protein deacetylase sirtuin-4 {ECO:0000255|HAMAP-Rule:MF_03161} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: NAD-dependent protein deacetylase sirtuin-4 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000089169(RPH3A)	--	0.196716595	8	0.072167962	5	0.057895794	4	0.132152827	12	0.151186928	4	0.551043206	51	--	--	--	--	--	--	1.77E-07	3.244897507	up	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; FYVE-type zinc finger	Rabphilin-3A GN=RPH3A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rabphilin-3A [Camelus ferus]
ENSG00000089177(KIF16B)	--	9.295912252	1011	9.380836066	1065	8.26634842	925	9.823673002	1113	8.495511565	985	7.923509646	898	0.975606832	0.107682332	normal	0.971787532	-0.133886606	normal	0.977539207	-0.050944826	normal	0.942238902	-0.024471923	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K17916|0|ptr:458104|KIF16B; kinesin family member 16B; K17916 kinesin family member 16B (A)	--	[Z]	Cytoskeleton	Kinesin motor domain;; FHA domain	Kinesin-like protein KIF16B GN=KIF16B OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF16B-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000089195(TRMT6)	--	18.32356	859	15.472685	731	15.373636	718	15.529967	732	16.43199	768	12.433651	582	0.926835197	-0.261140087	normal	0.974623087	0.049708017	normal	0.882469133	-0.310528272	normal	0.46315558	-0.170582843	normal	--	--	Biological Process: tRNA methylation (GO:0030488);; Cellular Component: tRNA (m1A) methyltransferase complex (GO:0031515);; 	K03256|0|ptr:747713|TRMT6; tRNA methyltransferase 6 homolog (S. cerevisiae); K03256 tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Gcd10p family	tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 GN=TRMT6 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [Orcinus orca]
ENSG00000089199(CHGB)	--	3.274372142	241	2.760642612	206	2.102932006	157	1.117585128	75	1.231563216	89	1.588654327	117	1.51E-10	-1.694407471	down	3.95E-05	-1.218180676	down	0.846027497	-0.427757017	normal	0.000554218	-1.124385216	down	--	--	Cellular Component: secretory granule (GO:0030141);; 	--	--	--	--	Granin (chromogranin or secretogranin)	CCB peptide (Precursor) GN=CHGB OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: secretogranin-1 [Galeopterus variegatus]
ENSG00000089220(PEBP1)	--	111.508	3152	118.393	3411	118.925	3409	153.913	4376	143.194	4016	161.105	4561	0.682354579	0.442329237	normal	0.978839742	0.214050418	normal	0.792368056	0.411551754	normal	0.024797462	0.356277968	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Phosphatidylethanolamine-binding protein	Hippocampal cholinergic neurostimulating peptide GN=PEBP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: phosphatidylethanolamine-binding protein 1 [Tupaia chinensis]
ENSG00000089234(BRAP)	--	7.64073125	540	9.47350166	593	8.831470062	573	9.597885004	700	10.171382	709	9.735418703	707	0.839710502	0.342704837	normal	0.937212203	0.235776466	normal	0.898537293	0.294183443	normal	0.146466158	0.289572511	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10632|0|hsa:8315|BRAP, BRAP2, IMP, RNF52; BRCA1 associated protein; K10632 BRCA1-associated protein [EC:6.3.2.19] (A)"	Ras signaling pathway (ko04014)	[R]	General function prediction only	"BRCA1-associated protein 2;; Zn-finger in ubiquitin-hydrolases and other protein;; Ring finger domain;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	BRCA1-associated protein OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: BRCA1-associated protein [Ailuropoda melanoleuca] 
ENSG00000089248(ERP29)	--	74.60747	2234	79.366222	2446	70.904802	2160	63.21681809	1887	59.232199	1745	97.83904	2919	0.945064579	-0.274161563	normal	0.343388483	-0.508249971	normal	0.698449338	0.425894022	normal	0.879049896	-0.082333047	normal	--	--	Cellular Component: endoplasmic reticulum (GO:0005783);; Cellular Component: endoplasmic reticulum lumen (GO:0005788);; Biological Process: protein secretion (GO:0009306);; 	K09586|1.70583e-171|ptr:738376|ERP29; endoplasmic reticulum protein 29; K09586 endoplasmic reticulum protein 29 (A)	Protein processing in endoplasmic reticulum (ko04141)	--	--	"ERp29, N-terminal domain;; Endoplasmic reticulum protein ERp29, C-terminal domain"	Endoplasmic reticulum resident protein 29 (Precursor) GN=ERP29 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: endoplasmic reticulum resident protein 29 [Oryctolagus cuniculus]
ENSG00000089250(NOS1)	--	0.349854583	89	0.245607067	63	0.339194359	87	0.150152523	38	0.232744655	59	0.163741	42	0.012244008	-1.225286453	normal	0.973391236	-0.113253537	normal	0.097294497	-1.032531395	normal	0.072332862	-0.802326867	normal	[PE]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism	Molecular Function: nitric-oxide synthase activity (GO:0004517);; Molecular Function: protein binding (GO:0005515);; Biological Process: nitric oxide biosynthetic process (GO:0006809);; Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13240|0|hsa:4842|NOS1, IHPS1, N-NOS, NC-NOS, NOS, bNOS, nNOS; nitric oxide synthase 1 (neuronal) (EC:1.14.13.39); K13240 nitric-oxide synthase, brain [EC:1.14.13.39] (A)"	Arginine and proline metabolism (ko00330);; Calcium signaling pathway (ko04020);; Phagosome (ko04145);; Circadian entrainment (ko04713);; Long-term depression (ko04730);; Salivary secretion (ko04970);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014)	[C]	Energy production and conversion	"Nitric oxide synthase, oxygenase domain;; FAD binding domain;; Flavodoxin;; Oxidoreductase NAD-binding domain;; PDZ domain (Also known as DHR or GLGF)"	"Nitric oxide synthase, brain GN=NOS1 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: nitric oxide synthase, brain [Tupaia chinensis]"
ENSG00000089280(FUS)	--	178.2387923	6304	216.0068653	8053	203.1899297	7459	192.5282154	6932	152.9837679	5492	186.0726831	6620	0.993365591	0.10614718	normal	0.189033989	-0.573489997	normal	0.990094869	-0.180403602	normal	0.31143052	-0.217466958	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K13098|3.77619e-91|ssc:100522185|FUS; fused in sarcoma; K13098 RNA-binding protein FUS (A)	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"Zn-finger in Ran binding protein and others;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein FUS GN=FUS OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: RNA-binding protein FUS isoform X4 [Sus scrofa]
ENSG00000089289(IGBP1)	--	36.82932	1123	34.66226	1067	30.34994	937	32.42657	1020	40.37377	1238	35.01319	1095	0.966992724	-0.169377753	normal	0.962785808	0.19277075	normal	0.95355286	0.216195396	normal	0.748078302	0.079514107	normal	--	--	Biological Process: regulation of signal transduction (GO:0009966);; 	"K17606|0|hsa:3476|IGBP1, ALPHA-4, IBP1; immunoglobulin (CD79A) binding protein 1; K17606 immunoglobulin-binding protein 1 (A)"	--	[T]	Signal transduction mechanisms	TAP42-like family	Immunoglobulin-binding protein 1 GN=IGBP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: immunoglobulin-binding protein 1-like isoform 1 [Dasypus novemcinctus]
ENSG00000089327(FXYD5)	--	103.0817608	1511	103.5262848	1502	107.939982	1618	117.9163999	1726	113.644471	1648	107.4260643	1591	0.97508389	0.160943344	normal	0.979992318	0.112296906	normal	0.984455459	-0.032538544	normal	0.737434437	0.079163464	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	K13362|1.78078e-116|ptr:744650|FXYD5; FXYD domain containing ion transport regulator 5; K13362 FXYD domain-containing ion transport regulator 5 (A)	--	--	--	ATP1G1/PLM/MAT8 family	FXYD domain-containing ion transport regulator 5 (Precursor) GN=FXYD5 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: FXYD domain-containing ion transport regulator 5 isoform X1 [Galeopterus variegatus] 
ENSG00000089335(ZNF302)	--	21.72999517	1051	22.6905661	1095	19.9911231	954	16.53294124	814	15.5568617	728	17.69163795	866	0.720607484	-0.398829637	normal	0.063838633	-0.609307368	normal	0.968474888	-0.147667887	normal	0.020545452	-0.38570391	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:55900|ZNF302, HSD16, MST154, MSTP154, ZNF135L, ZNF140L, ZNF327; zinc finger protein 302; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 302 GN=ZNF302 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 181-like isoform X7 [Tupaia chinensis]
ENSG00000089351(GRAMD1A)	--	75.066433	3919	68.14150019	3577	68.34199654	3565	85.970439	4562	106.381302	5587	115.7665014	6199	0.984490478	0.188280148	normal	0.056095908	0.621685211	normal	0.000390471	0.789584799	normal	0.00575232	0.54331485	normal	--	--	--	--	--	[S]	Function unknown	GRAM domain	GRAM domain-containing protein 1A GN=GRAMD1A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: GRAM domain-containing protein 1A isoform X2 [Canis lupus familiaris]
ENSG00000089356(FXYD3)	--	0	0	0.189475139	4	0.577779075	2	0	0	0	0	0.094367379	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	"K13361|2.71123e-101|hsa:5349|FXYD3, MAT8, PLML; FXYD domain containing ion transport regulator 3; K13361 FXYD domain-containing ion transport regulator 3 (A)"	--	--	--	ATP1G1/PLM/MAT8 family	FXYD domain-containing ion transport regulator 3 (Precursor) GN=FXYD3 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: FXYD domain-containing ion transport regulator 3 isoform X1 [Felis catus]
ENSG00000089472(HEPH)	--	0	0	0.020541939	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K14735|0|ggo:101139332|HEPH; hephaestin isoform 1; K14735 hephaestin [EC:1.16.3.1] (A)	Porphyrin and chlorophyll metabolism (ko00860);; Mineral absorption (ko04978)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Multicopper oxidase;; Multicopper oxidase	Hephaestin (Precursor) GN=HEPH OS=Homo sapiens (Human) PE=2 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: hephaestin [Odobenus rosmarus divergens]
ENSG00000089486(CDIP1)	--	7.998168935	335	6.199202961	284	8.69601527	350	9.862503289	325	7.248903554	309	7.243326189	304	0.965858791	-0.07420807	normal	0.962287627	0.099779886	normal	0.942690569	-0.2105978	normal	0.860646009	-0.068049748	normal	--	--	--	--	--	--	--	LITAF-like zinc ribbon domain	Cell death-inducing p53-target protein 1 GN=CDIP1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: cell death-inducing p53-target protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000089505(CMTM1)	--	86.20312144	976	65.084169	816	71.4987364	884	74.452661	1132	81.636907	1043	65.125857	812	0.963749933	0.182821236	normal	0.865425102	0.332125914	normal	0.969998335	-0.130624844	normal	0.623059952	0.136501281	normal	--	--	--	--	--	[V]	Defense mechanisms	--	CKLF-like MARVEL transmembrane domain-containing protein 1 GN=CMTM1 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: CKLF-like MARVEL transmembrane domain-containing protein 1 [Ursus maritimus]
ENSG00000089558(KCNH4)	--	0.440055771	20	0.259291817	11	0.375653294	13	0.48721755	20	0.425207295	20	0.19794444	14	0.989125045	-0.028632677	normal	0.972067409	0.762437021	normal	--	--	--	--	--	--	[T]	Signal transduction mechanisms	"Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; "	"K04907|0|hsa:23415|KCNH4, BEC2, ELK1, Kv12.3; potassium voltage-gated channel, subfamily H (eag-related), member 4; K04907 potassium voltage-gated channel Eag-related subfamily H member 4 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PAS domain;; Ion transport protein;; Ion channel;; PAS fold;; PAS fold;; PAS fold;; Cyclic nucleotide-binding domain	Potassium voltage-gated channel subfamily H member 4 GN=KCNH4 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily H member 4 [Vicugna pacos]
ENSG00000089597(GANAB)	--	137.0121462	9662	126.5883691	8990	134.0771711	9487	142.6397304	9963	136.6220202	9514	145.1207258	10180	0.996201146	0.013424005	normal	0.995527825	0.060294492	normal	0.99541622	0.093407891	normal	0.845964132	0.054701799	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K05546|0|mcc:718672|GANAB; glucosidase, alpha; neutral AB (EC:3.2.1.84); K05546 alpha 1,3-glucosidase [EC:3.2.1.84] (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[GMO]	"Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	Glycosyl hydrolases family 31;; Galactose mutarotase-like	Neutral alpha-glucosidase AB (Precursor) GN=GANAB OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: neutral alpha-glucosidase AB isoform X1 [Ailuropoda melanoleuca]
ENSG00000089682(RBM41)	--	12.291328	958	8.917649293	932	10.83021844	956	11.51378977	1072	13.715001	1110	11.40491055	1177	0.972353318	0.131176139	normal	0.948222917	0.230388352	normal	0.912106266	0.29132432	normal	0.248287699	0.218218137	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 41 GN=RBM41 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: RNA-binding protein 41 isoform X1 [Equus caballus]
ENSG00000089685(BIRC5)	--	63.5067043	2614	58.406236	2439	61.81272	2588	66.407418	2749	62.91181	2562	52.068647	2165	0.989000591	0.041791549	normal	0.987944613	0.049524198	normal	0.953767283	-0.265592112	normal	0.837129318	-0.053317085	normal	--	--	--	K08731|4.27211e-81|pon:100172652|BIRC5; baculoviral IAP repeat containing 5; K08731 baculoviral IAP repeat-containing protein 5 (A)	Hippo signaling pathway (ko04390);; Hepatitis B (ko05161);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210)	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Inhibitor of Apoptosis domain	Baculoviral IAP repeat-containing protein 5 GN=BIRC5 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	survivin [Canis lupus familiaris]
ENSG00000089692(LAG3)	--	0.329815311	11	0.400007231	10	0.472178128	14	0.449666978	16	0.401743788	14	0.076801545	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06565|0|hsa:3902|LAG3, CD223; lymphocyte-activation gene 3; K06565 lymphocyte-activation gene 3 protein (A)"	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	Lymphocyte activation gene 3 protein (Precursor) GN=LAG3 OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: lymphocyte activation gene 3 protein [Odobenus rosmarus divergens]
ENSG00000089693(MLF2)	--	164.72011	4697	144.859404	4301	158.266488	4664	133.54183	3862	134.6287381	3803	126.635181	3707	0.945824392	-0.313110522	normal	0.982449855	-0.198886324	normal	0.923237542	-0.339483361	normal	0.090177124	-0.285906684	normal	--	--	--	--	--	[S]	Function unknown	Myelodysplasia-myeloid leukemia factor 1-interacting protein	Myeloid leukemia factor 2 GN=MLF2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: myeloid leukemia factor 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000089723(OTUB2)	--	2.54993	184	1.55455	112	2.52976	182	3.814353	266	3.29149	236	1.57615	114	0.602966775	0.497416681	normal	0.000505205	1.043938047	up	0.266712613	-0.676033338	normal	0.639587765	0.34305998	normal	--	--	--	"K09603|1.79289e-172|nle:100582681|OTUB2; OTU domain, ubiquitin aldehyde binding 2; K09603 ubiquitin thioesterase protein OTUB2 [EC:3.4.19.12] (A)"	--	[S]	Function unknown	Peptidase C65 Otubain;; OTU-like cysteine protease	Ubiquitin thioesterase OTUB2 GN=OTUB2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ubiquitin thioesterase OTUB2 [Vicugna pacos]
ENSG00000089737(DDX24)	--	49.82522945	2659	46.22626559	2554	54.05060213	2893	56.4150162	3118	57.96945008	3060	45.68628878	2442	0.97776794	0.198798727	normal	0.968030951	0.239217019	normal	0.962188453	-0.252650632	normal	0.783100145	0.067040532	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	K14805|0|hsa:57062|DDX24; DEAD (Asp-Glu-Ala-Asp) box helicase 24 (EC:3.6.4.13); K14805 ATP-dependent RNA helicase DDX24/MAK5 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; SNF2 family N-terminal domain	ATP-dependent RNA helicase DDX24 GN=DDX24 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX24 [Ceratotherium simum simum]
ENSG00000089775(ZBTB25)	--	6.644431657	480	7.409447845	535	7.359490006	514	6.067160135	393	4.368820484	348	6.356657175	517	0.874157486	-0.318209437	normal	0.068076468	-0.63961804	normal	0.972150071	0.000104173	normal	0.20798461	-0.301864543	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10504|0|hsa:7597|ZBTB25, C14orf51, KUP, ZNF46; zinc finger and BTB domain containing 25; K10504 zinc finger and BTB domain-containing protein 25 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2 type zinc-finger (2 copies)"	Zinc finger and BTB domain-containing protein 25 GN=ZBTB25 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 25 isoform X1 [Equus caballus] 
ENSG00000089818(NECAP1)	--	8.7649499	343	8.100546651	311	11.81205204	405	9.586358673	369	9.1548534	351	9.053431981	363	0.966311471	0.074259246	normal	0.955716233	0.152431873	normal	0.954909889	-0.165590332	normal	0.985016047	0.011489143	normal	--	--	Biological Process: endocytosis (GO:0006897);; Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1681)	Adaptin ear-binding coat-associated protein 1 GN=NECAP1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: adaptin ear-binding coat-associated protein 1 [Tupaia chinensis]
ENSG00000089820(ARHGAP4)	--	1.55595939	90	1.149151487	58	1.670574416	75	0.990146006	29	1.185190081	51	0.791788582	73	0.000127273	-1.61361109	down	0.971332458	-0.201378328	normal	0.97370863	-0.046338462	normal	0.313585257	-0.561948456	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[Z]	Cytoskeleton	"RhoGAP domain;; Fes/CIP4, and EFC/F-BAR homology domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain"	Rho GTPase-activating protein 4 GN=ARHGAP4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 4 [Ceratotherium simum simum]
ENSG00000089847(ANKRD24)	--	0.705625552	56	0.274042771	23	0.426298546	29	0.44021212	35	0.434154658	31	0.398225935	27	0.860921658	-0.684911727	normal	0.976962713	0.387212669	normal	0.98502867	-0.105672631	normal	0.809780975	-0.238031535	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 24 GN=ANKRD24 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 24 [Ceratotherium simum simum]
ENSG00000089876(DHX32)	--	18.891215	1182	19.03604654	1211	18.35653222	1136	23.339509	1486	24.744835	1549	22.71421238	1430	0.912133756	0.299024546	normal	0.878577823	0.333342844	normal	0.885032818	0.323376373	normal	0.052185335	0.318034425	normal	[L]	"Replication, recombination and repair"	Molecular Function: helicase activity (GO:0004386);; 	--	--	[A]	RNA processing and modification	Helicase associated domain (HA2);; Oligonucleotide/oligosaccharide-binding (OB)-fold	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 GN=DHX32 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32 [Tupaia chinensis] 
ENSG00000089902(RCOR1)	--	14.16846	1341	13.16493	1247	13.03015	1221	13.61511	1293	13.28329	1259	11.00079	1042	0.980254034	-0.083321994	normal	0.981672794	-0.007600567	normal	0.947820124	-0.236681683	normal	0.642280624	-0.105696095	normal	--	--	--	"K11829|0|hsa:23186|RCOR1, COREST, RCOR; REST corepressor 1; K11829 REST corepressor 1 (A)"	Huntington's disease (ko05016)	[K]	Transcription	Myb-like DNA-binding domain;; ELM2 domain	REST corepressor 1 GN=RCOR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: REST corepressor 1 [Odobenus rosmarus divergens]
ENSG00000089916(GPATCH2L)	--	12.30969081	1351	14.12735576	1517	14.53213169	1360	14.55952045	1773	15.09982351	1626	13.890831	1600	0.835276798	0.360973323	normal	0.982216127	0.078603919	normal	0.9581113	0.225941942	normal	0.218420975	0.220025561	normal	--	--	--	"K17569|0|ptr:742756|GPATCH2L, C14H14orf118, C14orf118; G patch domain containing 2-like; K17569 G patch domain-containing protein 2 (A)"	--	[R]	General function prediction only	--	G patch domain-containing protein 2-like GN=GPATCH2L OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: uncharacterized protein LOC100153141 isoform X1 [Sus scrofa]
ENSG00000090006(LTBP4)	--	47.40996619	3788	29.441998	2427	36.60193595	2853	33.97557232	2853	42.5145958	3615	24.13338073	2008	0.676386244	-0.439582611	normal	0.193599719	0.55311086	normal	0.299424342	-0.514684999	normal	0.853770503	-0.119346909	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K08023|0|hsa:8425|LTBP4, ARCL1C, LTBP-4, LTBP4L, LTBP4S; latent transforming growth factor beta binding protein 4; K08023 latent transforming growth factor beta binding protein (A)"	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; TB domain;; EGF-like domain;; EGF domain;; Coagulation Factor Xa inhibitory site	Latent-transforming growth factor beta-binding protein 4 (Precursor) GN=LTBP4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: latent-transforming growth factor beta-binding protein 4 [Bison bison bison]
ENSG00000090013(BLVRB)	--	270.34435	3516	301.0838	4040	256.31564	3450	203.90606	2706	216.59872	2799	244.176	3194	0.775429309	-0.408401391	normal	0.209917999	-0.550621239	normal	0.987903815	-0.119469049	normal	0.021502562	-0.36025507	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K05901|2.46006e-136|hsa:645|BLVRB, BVRB, FLR, HEL-S-10, SDR43U1; biliverdin reductase B (EC:1.3.1.24 1.5.1.30); K05901 biliverdin reductase / flavin reductase [EC:1.3.1.24 1.5.1.30] (A)"	Riboflavin metabolism (ko00740);; Porphyrin and chlorophyll metabolism (ko00860)	--	--	NADH(P)-binding;; NmrA-like family;; NAD dependent epimerase/dehydratase family;; 3-beta hydroxysteroid dehydrogenase/isomerase family	Flavin reductase (NADPH) GN=BLVRB OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: flavin reductase (NADPH) [Ailuropoda melanoleuca]
ENSG00000090020(SLC9A1)	--	7.065722	573	6.021804	465	6.637231	543	8.779018	711	10.299712	819	8.116851465	674	0.910147138	0.279807583	normal	0.001415202	0.793237771	normal	0.889931827	0.302746759	normal	0.009874903	0.458158616	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K05742|0|hsa:6548|SLC9A1, APNH, NHE-1, NHE1, PPP1R143; solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1; K05742 solute carrier family 9 (sodium/hydrogen exchanger), member 1 (A)"	cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Regulation of actin cytoskeleton (ko04810);; Thyroid hormone signaling pathway (ko04919);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Proteoglycans in cancer (ko05205)	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 1 GN=SLC9A1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 1 [Mustela putorius furo] 
ENSG00000090054(SPTLC1)	--	35.235378	1513	34.544902	1476	35.2233385	1510	35.34957733	1563	34.0466569	1493	36.01207	1550	0.984225878	0.016057484	normal	0.983541295	-0.004900122	normal	0.984021137	0.029399162	normal	0.971095564	0.012702694	normal	[H]	Coenzyme transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00654|0|ptr:464590|SPTLC1; serine palmitoyltransferase, long chain base subunit 1 (EC:2.3.1.50); K00654 serine palmitoyltransferase [EC:2.3.1.50] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[O]	"Posttranslational modification, protein turnover, chaperones"	Aminotransferase class I and II	Serine palmitoyltransferase 1 GN=SPTLC1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine palmitoyltransferase 1-like [Echinops telfairi]
ENSG00000090060(PAPOLA)	--	69.63744134	4607	73.57250936	4728	74.92560948	4849	71.88271815	4862	70.10880336	4718	72.4089814	4623	0.992824392	0.046874814	normal	0.992805233	-0.024473339	normal	0.992220507	-0.077124696	normal	0.953328303	-0.019346822	normal	[A]	RNA processing and modification	Molecular Function: RNA binding (GO:0003723);; Molecular Function: polynucleotide adenylyltransferase activity (GO:0004652);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; Biological Process: RNA polyadenylation (GO:0043631);; 	K14376|0|ptr:100614622|PAPOLA; poly(A) polymerase alpha; K14376 poly(A) polymerase [EC:2.7.7.19] (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Poly(A) polymerase central domain;; Poly(A) polymerase predicted RNA binding domain;; Nucleotidyltransferase domain	Poly(A) polymerase alpha GN=PAPOLA OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: poly(A) polymerase alpha isoform X4 [Tupaia chinensis]
ENSG00000090061(CCNK)	--	18.349259	576	24.097018	747	23.378355	716	27.518426	839	23.54063919	718	25.3858816	825	0.313014426	0.510635286	normal	0.972747063	-0.078389071	normal	0.955132688	0.19575761	normal	0.336379449	0.203092429	normal	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	Cellular Component: nucleus (GO:0005634);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-K GN=CCNK OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	cyclin-K [Bos taurus] 
ENSG00000090097(PCBP4)	--	39.80939166	1135	29.02904861	888	30.13567468	998	33.44130436	973	30.98991346	873	31.53836016	869	0.938147123	-0.252643014	normal	0.976750492	-0.045925697	normal	0.954820375	-0.207637608	normal	0.393339222	-0.175608644	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K13162|0|ptr:460410|PCBP4; poly(rC) binding protein 4; K13162 poly(rC)-binding protein 2/3/4 (A)	--	[AR]	RNA processing and modification;; General function prediction only	KH domain;; KH domain;; KH domain;; KH domain	Poly(rC)-binding protein 4 GN=PCBP4 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: poly(rC)-binding protein 4 isoform X3 [Sus scrofa]
ENSG00000090104(RGS1)	--	0	0	0	0	0	0	0	0	0.0411634	0	0.0839988	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16449|8.82075e-154|ptr:457594|RGS1; regulator of G-protein signaling 1; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 1 GN=RGS1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 1 isoform X2 [Felis catus] 
ENSG00000090238(YPEL3)	--	12.49663315	175	10.44269349	163	9.649877068	149	10.02794069	156	11.66751697	173	14.35739967	230	0.952367574	-0.194828137	normal	0.964722339	0.063898037	normal	0.320467197	0.612984786	normal	0.666230489	0.178696564	normal	--	--	--	--	--	[R]	General function prediction only	"Yippee zinc-binding/DNA-binding /Mis18, centromere assembly"	Protein yippee-like 3 GN=YPEL3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: protein yippee-like 3 [Ursus maritimus]
ENSG00000090263(MRPS33)	--	41.77688524	612	40.33868965	626	43.03672981	626	42.7523303	637	38.5801779	569	49.26328935	726	0.973788131	0.026863353	normal	0.959886202	-0.158758091	normal	0.950167388	0.205055072	normal	0.929003287	0.030859386	normal	--	--	--	K17411|1.63887e-54|ptr:463782|MRPS33; mitochondrial ribosomal protein S33; K17411 small subunit ribosomal protein S33 (A)	--	[T]	Signal transduction mechanisms	Mitochondrial ribosomal subunit S27	"28S ribosomal protein S33, mitochondrial GN=MRPS33 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S33, mitochondrial [Camelus ferus] "
ENSG00000090266(NDUFB2)	--	185.7317197	1434	198.686	1521	202.6190023	1636	213.1742798	1694	191.19294	1391	212.1769973	1536	0.964345161	0.209350037	normal	0.974815433	-0.150168095	normal	0.981473369	-0.099191328	normal	0.972775049	-0.012000329	normal	--	--	--	"K03958|1.29991e-58|hsa:4708|NDUFB2, AGGG, CI-AGGG; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa (EC:1.6.5.3 1.6.99.3); K03958 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 2 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	NADH dehydrogenase 1 beta subcomplex subunit 2	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial (Precursor) GN=NDUFB2 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial precursor [Bos taurus] "
ENSG00000090273(NUDC)	--	59.47747377	2310	62.30844761	2520	68.32838921	2752	68.1694666	2696	65.29676934	2519	50.40518003	1971	0.97673896	0.191977103	normal	0.98846242	-0.021985973	normal	0.411560111	-0.489524746	normal	0.713737845	-0.099239434	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	N-terminal conserved domain of Nudc.;; CS domain	Nuclear migration protein nudC GN=NUDC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: nuclear migration protein nudC [Erinaceus europaeus]
ENSG00000090316(MAEA)	--	23.52266537	956	23.26801941	956	23.43273715	972	25.444039	1045	23.70628848	972	22.23588486	894	0.975740264	0.09743835	normal	0.978649353	0.002515192	normal	0.971586444	-0.128763961	normal	0.985354717	-0.008185395	normal	--	--	--	K18624|0|tup:102494787|MAEA; macrophage erythroblast attacher; K18624 macrophage erythroblast attacher (A)	--	[S]	Function unknown	CTLH/CRA C-terminal to LisH motif domain	Macrophage erythroblast attacher GN=MAEA OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: macrophage erythroblast attacher isoform X1 [Bubalus bubalis]
ENSG00000090339(ICAM1)	--	1.906506745	102	1.374723016	94	0.99477402	69	1.564995174	106	3.83439442	246	5.223539506	348	0.970524695	0.024303739	normal	6.71E-07	1.352550405	up	0	2.301211981	up	0.130098297	1.382815561	normal	--	--	--	"K06490|0|hsa:3383|ICAM1, BB2, CD54, P3.58; intercellular adhesion molecule 1; K06490 intercellular adhesion molecule 1 (A)"	NF-kappa B signaling pathway (ko04064);; Cell adhesion molecules (CAMs) (ko04514);; Natural killer cell mediated cytotoxicity (ko04650);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; African trypanosomiasis (ko05143);; Malaria (ko05144);; Staphylococcus aureus infection (ko05150);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Rheumatoid arthritis (ko05323);; Viral myocarditis (ko05416)	--	--	"Intercellular adhesion molecule (ICAM), N-terminal domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain"	Intercellular adhesion molecule 1 (Precursor) GN=ICAM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: intercellular adhesion molecule 1 [Balaenoptera acutorostrata scammoni]
ENSG00000090372(STRN4)	--	40.2184693	2473	37.17094625	2371	35.69483136	2358	31.57737387	2007	37.47828066	2334	33.60178301	2126	0.899957224	-0.331824546	normal	0.987533225	-0.044089316	normal	0.980255926	-0.157607058	normal	0.351219896	-0.176293932	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17608|0|hsa:29888|STRN4, ZIN, zinedin; striatin, calmodulin binding protein 4; K17608 striatin 1/3/4 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"WD domain, G-beta repeat;; Striatin family;; Nucleoporin Nup120/160"	Striatin-4 GN=STRN4 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: striatin-4 [Sus scrofa]
ENSG00000090376(IRAK3)	--	0.029591112	4	0.03562451	5	0.044339111	5	0.088260654	12	0.280344537	20	0.4520165	41	--	--	--	0.689662297	1.705740547	normal	0.000109128	2.699462453	up	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; 	K04732|0|pps:100983022|IRAK3; interleukin-1 receptor-associated kinase 3; K04732 interleukin-1 receptor-associated kinase 3 [EC:2.7.11.1] (A)	Apoptosis (ko04210);; Neurotrophin signaling pathway (ko04722)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Death domain	Interleukin-1 receptor-associated kinase 3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor-associated kinase 3 [Physeter catodon]
ENSG00000090382(LYZ)	--	0	0	2.769702511	60	3.028605082	65	0	0	0.0447174	0	0.051278314	1	--	--	--	1.32E-13	-5.356557465	down	1.84E-13	-4.732250602	down	--	--	--	--	--	--	"K13915|1.45892e-104|ptr:450190|LYZ, LZM; lysozyme (EC:3.2.1.17); K13915 lysozyme C [EC:3.2.1.17] (A)"	Salivary secretion (ko04970)	--	--	C-type lysozyme/alpha-lactalbumin family;; Transglycosylase SLT domain	Lysozyme C (Precursor) GN=LYZ OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	lysozyme C [Chaerephon plicatus]
ENSG00000090432(MUL1)	--	17.9661	815	16.505	765	16.674	769	18.1662	822	20.7089	931	19.4037	879	0.977076982	-0.018459279	normal	0.928672101	0.261425768	normal	0.959383582	0.184248988	normal	0.528927261	0.143137775	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Biological Process: organelle organization (GO:0006996);; Biological Process: protein ubiquitination (GO:0016567);; 	K15688|0|pps:100972926|MUL1; mitochondrial E3 ubiquitin protein ligase 1; K15688 E3 ubiquitin-protein ligase MUL1 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"E3 Ubiquitin ligase;; Zinc finger, C3HC4 type (RING finger)"	Mitochondrial ubiquitin ligase activator of NFKB 1 GN=MUL1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial ubiquitin ligase activator of NFKB 1 [Galeopterus variegatus]
ENSG00000090447(TFAP4)	--	8.262348338	270	6.132234771	271	9.197262054	274	9.508263446	306	12.23483785	412	15.66146596	439	0.956907266	0.148943504	normal	0.226548468	0.580280987	normal	0.051766948	0.668811143	normal	0.041850464	0.485458888	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09108|2.81928e-155|hsa:7023|TFAP4, AP-4, bHLHc41; transcription factor AP-4 (activating enhancer binding protein 4); K09108 transcription factor AP-4 (A)"	Proteoglycans in cancer (ko05205)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Transcription factor AP-4 GN=TFAP4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor AP-4 [Trichechus manatus latirostris]
ENSG00000090470(PDCD7)	--	13.53841	629	14.84885	714	13.0666	624	17.34454	829	18.666394	883	17.02008	805	0.797292277	0.366697516	normal	0.911405455	0.284520043	normal	0.814224708	0.358384643	normal	0.06615592	0.334318586	normal	--	--	--	--	--	--	--	--	Programmed cell death protein 7 GN=PDCD7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: programmed cell death protein 7 [Oryctolagus cuniculus]
ENSG00000090487(SPG21)	--	104.045455	2630	104.0900872	2668	101.6197426	2583	85.284918	2148	87.26068051	2161	92.81741293	2348	0.913222939	-0.322692044	normal	0.914010144	-0.325280856	normal	0.982757439	-0.145817096	normal	0.116442058	-0.264483238	normal	--	--	--	--	--	--	--	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Maspardin GN=SPG21 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: maspardin isoform X1 [Orycteropus afer afer] 
ENSG00000090512(FETUB)	--	0.219652365	2	0.095376739	2	0.176696179	4	0.27917589	6	0.138329884	3	0.420885333	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	--	--	--	--	Cystatin domain	Fetuin-B (Precursor) GN=FETUB OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: fetuin-B [Pteropus alecto]
ENSG00000090520(DNAJB11)	--	31.35468244	974	27.890929	881	31.47962	924	30.34148395	955	33.98733	1011	30.519928	885	0.977785209	-0.059159055	normal	0.963039257	0.176858946	normal	0.976487691	-0.070389112	normal	0.965475915	0.015554527	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09517|0|pps:100992108|DNAJB11; DnaJ (Hsp40) homolog, subfamily B, member 11; K09517 DnaJ homolog subfamily B member 11 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ C terminal domain;; DnaJ domain	DnaJ homolog subfamily B member 11 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 11 [Pteropus alecto]
ENSG00000090530(P3H2)	--	23.03105491	1445	19.14283203	1209	23.89729482	1491	16.23659168	1024	15.86663138	994	14.61342767	914	0.226362226	-0.527016689	normal	0.903597997	-0.303503595	normal	0.004134848	-0.713372047	normal	0.000491012	-0.520754484	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[S]	Function unknown	2OG-Fe(II) oxygenase superfamily;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; 2OG-Fe(II) oxygenase superfamily	Prolyl 3-hydroxylase 2 (Precursor) GN=LEPREL1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prolyl 3-hydroxylase 2 isoform X1 [Felis catus]
ENSG00000090534(THPO)	--	0	0	0.0303404	1	0.0318515	0	0	0	0.071669697	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	"K06854|0|hsa:7066|THPO, MGDF, MKCSF, ML, MPLLG, THCYT1, TPO; thrombopoietin; K06854 thrombopoietin (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640)	--	--	Erythropoietin/thrombopoietin	Thrombopoietin (Precursor) GN=THPO OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: thrombopoietin isoform X3 [Galeopterus variegatus]
ENSG00000090539(CHRD)	--	0.06309942	4	0.03330789	2	0.090586176	5	0	0	0.184139416	11	0.051588542	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K04657|0|hsa:8646|CHRD; chordin; K04657 chordin (A)	TGF-beta signaling pathway (ko04350)	--	--	CHRD domain;; von Willebrand factor type C domain	Chordin (Precursor) GN=CHRD OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: chordin isoformX1 [Canis lupus familiaris]
ENSG00000090554(FLT3LG)	--	1.392042895	20	0.676476328	11	0.922196324	12	2.402094	37	2.307908919	32	4.978943666	65	0.904732527	0.810324781	normal	0.492218753	1.401696623	normal	5.56E-06	2.291615742	up	0.021666734	1.620037382	normal	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: membrane (GO:0016020);; 	"K05454|1.29987e-121|hsa:2323|FLT3LG, FL, FLT3L; fms-related tyrosine kinase 3 ligand; K05454 fms-related tyrosine kinase 3 ligand (A)"	Cytokine-cytokine receptor interaction (ko04060);; Hematopoietic cell lineage (ko04640);; Pathways in cancer (ko05200)	--	--	flt3 ligand	Fms-related tyrosine kinase 3 ligand (Precursor) GN=FLT3LG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fms-related tyrosine kinase 3 ligand isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000090565(RAB11FIP3)	--	13.55712989	1041	13.27603007	1064	14.64718083	1085	14.8490341	1142	16.06189849	1254	14.688037	1175	0.97643361	0.102615692	normal	0.956415949	0.215330469	normal	0.976623118	0.106531555	normal	0.506811968	0.141761934	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K12485|0|mcc:722300|RAB11FIP3; RAB11 family interacting protein 3 (class II); K12485 Rab11 family-interacting protein 3/4 (A)	Endocytosis (ko04144)	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	FIP domain;; EF-hand domain pair	Rab11 family-interacting protein 3 GN=RAB11FIP3 OS=Homo sapiens (Human) PE=1 SV=1	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: rab11 family-interacting protein 3 [Ceratotherium simum simum]
ENSG00000090581(GNPTG)	--	14.48986	457	15.59984	442	13.77545	456	15.902346	466	16.55291	463	19.803384	535	0.970950647	-0.002687526	normal	0.969118151	0.045387534	normal	0.940361214	0.221534669	normal	0.76888455	0.090864591	normal	--	--	--	"K10087|0|hsa:84572|GNPTG, C16orf27, GNPTAG, LP2537, RJD9; N-acetylglucosamine-1-phosphate transferase, gamma subunit; K10087 N-acetylglucosamine-1-phosphate transferase, gamma subunit (A)"	Lysosome (ko04142)	[T]	Signal transduction mechanisms	Glucosidase II beta subunit-like protein;; Glucosidase II beta subunit-like protein	N-acetylglucosamine-1-phosphotransferase subunit gamma (Precursor) GN=GNPTG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: N-acetylglucosamine-1-phosphotransferase subunit gamma [Ceratotherium simum simum]
ENSG00000090612(ZNF268)	--	9.159025309	579	10.63758182	626	9.516425686	567	10.31447097	605	8.837936844	562	11.50042258	682	0.97304929	0.032455279	normal	0.9559028	-0.176568629	normal	0.925327328	0.2575045	normal	0.902702768	0.040373685	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:10795|ZNF268, HZF3; zinc finger protein 268; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; TFIIH C1-like domain;; CpXC protein"	Zinc finger protein 268 GN=ZNF268 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 268 [Galeopterus variegatus]
ENSG00000090615(GOLGA3)	--	12.68701244	2335	15.67046941	2897	15.20355191	2876	15.69807629	3024	15.19061442	2860	18.660124	3480	0.896921322	0.34200512	normal	0.98930388	-0.039950106	normal	0.961087571	0.266604564	normal	0.358760824	0.187106631	normal	--	--	--	--	--	--	--	--	Golgin subfamily A member 3 GN=GOLGA3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: golgin subfamily A member 3 isoform X1 [Galeopterus variegatus]
ENSG00000090621(PABPC4)	--	51.37993794	2805	50.70790928	2835	52.32000998	2930	63.27393577	3344	57.98983003	3157	54.54877344	2847	0.973992137	0.222630019	normal	0.985709477	0.133711354	normal	0.989432164	-0.049723577	normal	0.636377246	0.103767059	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	"K13126|0|pps:100991725|PABPC4; poly(A) binding protein, cytoplasmic 4 (inducible form); K13126 polyadenylate-binding protein (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; RNA degradation (ko03018)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Poly-adenylate binding protein, unique domain;; Limkain b1;; Nup53/35/40-type RNA recognition motif;; RNA binding motif"	Polyadenylate-binding protein 4 GN=PABPC4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: polyadenylate-binding protein 4 isoform X1 [Tupaia chinensis]
ENSG00000090661(CERS4)	--	7.029272678	178	3.617708362	102	5.704541752	145	2.66503399	81	4.819065391	133	2.22451034	70	0.000321354	-1.151586586	down	0.911617178	0.35678633	normal	0.006683771	-1.042919577	down	0.257698996	-0.602633454	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: DNA binding (GO:0003677);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04710|0|hsa:79603|CERS4, LASS4, Trh1; ceramide synthase 4; K04710 ceramide synthetase [EC:2.3.1.24] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TLC domain;; Homeobox domain	Ceramide synthase 4 GN=CERS4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ceramide synthase 4 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000090686(USP48)	--	16.026842	1002	13.27009594	869	16.05880125	1010	15.32666021	1035	14.14953867	947	12.65748493	807	0.979666431	0.01589202	normal	0.973577031	0.102410935	normal	0.862536802	-0.33144973	normal	0.79658904	-0.068574018	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11858|0|ptr:456602|USP48; ubiquitin specific peptidase 48; K11858 ubiquitin carboxyl-terminal hydrolase 48 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; DUSP domain;; Ubiquitin family	Ubiquitin carboxyl-terminal hydrolase 48 GN=USP48 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 48 isoform X2 [Loxodonta africana]
ENSG00000090776(EFNB1)	--	3.85053	245	3.03931	197	3.80705	249	3.92392	249	4.35066	275	3.13527	201	0.967102758	-0.007422102	normal	0.698291431	0.456828925	normal	0.898573127	-0.315107377	normal	0.916784659	0.047868022	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K05463|0|hsa:1947|EFNB1, CFND, CFNS, EFB1, EFL3, EPLG2, Elk-L, LERK2; ephrin-B1; K05463 ephrin-B (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Ephrin	Ephrin-B1 (Precursor) GN=EFNB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ephrin-B1 [Galeopterus variegatus]
ENSG00000090857(PDPR)	--	15.28778644	2139	16.73620937	2246	14.89887725	2153	13.25941933	1827	14.06026306	1995	16.93877643	2415	0.952212473	-0.258091258	normal	0.973910861	-0.192258286	normal	0.980534292	0.157279066	normal	0.702980715	-0.088390643	normal	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K17509|0|hsa:55066|PDPR, PDP3; pyruvate dehydrogenase phosphatase regulatory subunit (EC:1.5.8.4); K17509 pyruvate dehydrogenase phosphatase regulatory subunit (A)"	--	[E]	Amino acid transport and metabolism	FAD dependent oxidoreductase;; Aminomethyltransferase folate-binding domain;; Glycine cleavage T-protein C-terminal barrel domain;; FAD binding domain;; Thi4 family;; FAD binding domain	"Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial (Precursor) GN=PDPR OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial isoformX2 [Equus caballus] "
ENSG00000090861(AARS)	--	121.55164	9065	121.07872	9292	114.85319	8650	74.52307	5597	75.229835	5635	131.37806	9887	0.003246573	-0.726327211	normal	0.002771651	-0.742843136	normal	0.991790744	0.184511064	normal	0.350283491	-0.374374717	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: alanine-tRNA ligase activity (GO:0004813);; Molecular Function: ATP binding (GO:0005524);; Biological Process: alanyl-tRNA aminoacylation (GO:0006419);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	"K01872|0|hsa:16|AARS, CMT2N; alanyl-tRNA synthetase (EC:6.1.1.7); K01872 alanyl-tRNA synthetase [EC:6.1.1.7] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class II (A);; Threonyl and Alanyl tRNA synthetase second additional domain;; DHHA1 domain	"Alanine--tRNA ligase, cytoplasmic {ECO:0000255|HAMAP-Rule:MF_03133} OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: alanine--tRNA ligase, cytoplasmic [Ceratotherium simum simum]"
ENSG00000090863(GLG1)	--	38.69588819	4410	35.22110258	4007	36.94231469	3985	40.18774672	4407	37.02372865	4240	36.95921804	4027	0.992595913	-0.031802939	normal	0.991507403	0.060093148	normal	0.992152353	0.006831727	normal	0.977448148	0.009766112	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K06816|0|hsa:2734|GLG1, CFR-1, ESL-1, MG-160, MG160; golgi glycoprotein 1; K06816 golgi apparatus protein 1 (A)"	Cell adhesion molecules (CAMs) (ko04514)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cysteine rich repeat	Golgi apparatus protein 1 (Precursor) GN=GLG1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi apparatus protein 1-like isoform X2 [Physeter catodon]
ENSG00000090889(KIF4A)	--	15.0568	1594	15.5211	1648	15.2512	1604	14.3889	1522	13.3444	1403	13.4726	1423	0.981351217	-0.097419422	normal	0.947941507	-0.253375479	normal	0.970607464	-0.180848776	normal	0.353497208	-0.177885483	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10395|0|ggo:101127650|KIF4A; chromosome-associated kinesin KIF4A; K10395 kinesin family member 4/21/27 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Chromosome-associated kinesin KIF4A GN=KIF4A OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: chromosome-associated kinesin KIF4A isoform X2 [Canis lupus familiaris] 
ENSG00000090905(TNRC6A)	--	16.338762	2323	18.88454075	2664	17.8705062	2557	15.124907	2302	17.17702457	2537	17.32508648	2398	0.987707304	-0.043904413	normal	0.986844703	-0.091843687	normal	0.986214577	-0.10085034	normal	0.727453367	-0.080945576	normal	--	--	--	"K18412|0|hsa:27327|TNRC6A, CAGH26, GW1, GW182, TNRC6; trinucleotide repeat containing 6A; K18412 trinucleotide repeat-containing gene 6 protein (A)"	--	--	--	"Argonaute hook;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Trinucleotide repeat-containing gene 6A protein GN=TNRC6A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: trinucleotide repeat-containing gene 6A protein [Tupaia chinensis]
ENSG00000090924(PLEKHG2)	--	17.73285719	2103	15.80151886	1766	16.33930839	2056	17.91451703	2075	15.90403907	1988	17.49072303	1943	0.986630723	-0.050132903	normal	0.978573281	0.149285316	normal	0.984644651	-0.089777866	normal	0.999834061	-0.001656031	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[R]	General function prediction only	RhoGEF domain	Pleckstrin homology domain-containing family G member 2 GN=PLEKHG2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family G member 2 [Lipotes vexillifer]
ENSG00000090932(DLL3)	--	7.056981409	187	6.562797254	179	6.6650774	184	5.40113062	146	4.353076	117	4.301286888	114	0.863992916	-0.384318074	normal	0.399314211	-0.628260491	normal	0.225904047	-0.691671789	normal	0.070744768	-0.566862534	normal	--	--	--	"K06051|0|hsa:10683|DLL3, SCDO1; delta-like 3 (Drosophila); K06051 delta (A)"	Notch signaling pathway (ko04330)	[T]	Signal transduction mechanisms	EGF-like domain;; N terminus of Notch ligand;; Human growth factor-like EGF;; EGF-like domain	Delta-like protein 3 (Precursor) GN=DLL3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: delta-like protein 3 [Orcinus orca]
ENSG00000090971(NAT14)	--	40.833341	924	37.49099258	865	40.80262003	958	35.30767942	796	38.79423427	864	30.74118357	692	0.937324016	-0.245516318	normal	0.977148175	-0.023055048	normal	0.437444334	-0.476655705	normal	0.199663936	-0.245344966	normal	--	--	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	--	--	--	--	Acetyltransferase (GNAT) family	N-acetyltransferase 14 GN=NAT14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: N-acetyltransferase 14 [Sorex araneus]
ENSG00000090975(PITPNM2)	--	4.508894999	641	4.87336972	717	5.3357603	761	5.436955751	767	5.994721479	820	4.921479995	688	0.942048554	0.227570795	normal	0.960741619	0.171885036	normal	0.96414552	-0.153458451	normal	0.76379774	0.081225951	normal	[R]	General function prediction only	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Phosphatidylinositol transfer protein;; DDHD domain;; LNS2 (Lipin/Ned1/Smp2)	Membrane-associated phosphatidylinositol transfer protein 2 GN=PITPNM2 OS=Homo sapiens (Human) PE=1 SV=1	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: membrane-associated phosphatidylinositol transfer protein 2 isoform X2 [Oryctolagus cuniculus]
ENSG00000090989(EXOC1)	--	9.7246925	653	10.34679392	677	10.40160668	686	8.891587	598	9.223891168	612	9.378581782	631	0.961244443	-0.157382632	normal	0.959281853	-0.166658976	normal	0.966877854	-0.128564402	normal	0.527673909	-0.151979876	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: exocytosis (GO:0006887);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec3;; Exocyst complex component SEC3 N-terminal PIP2 binding PH	Exocyst complex component 1 GN=EXOC1 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 1 isoform X1 [Vicugna pacos]
ENSG00000091009(RBM27)	--	12.29126787	1409	12.15745108	1460	12.94972108	1446	11.8728031	1422	11.94609341	1399	9.2529622	1106	0.983337584	-0.017563347	normal	0.980880446	-0.082911222	normal	0.745514205	-0.394534339	normal	0.431907814	-0.15779712	normal	--	--	Biological Process: mRNA processing (GO:0006397);; Molecular Function: metal ion binding (GO:0046872);; 	"K13193|0|hsa:54439|RBM27, ARRS1, Psc1, ZC3H18; RNA binding motif protein 27; K13193 RNA-binding protein 27 (A)"	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; PWI domain;; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 27 GN=RBM27 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: uncharacterized protein LOC101399697 [Ceratotherium simum simum]
ENSG00000091039(OSBPL8)	--	22.80076064	1637	23.75314006	1741	15.9025393	1717	28.74982457	2158	23.56036757	1621	25.03653638	1933	0.83433601	0.367507054	normal	0.979772756	-0.1243467	normal	0.976708589	0.162525172	normal	0.479267196	0.143273798	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Oxysterol-binding protein;; PH domain	Oxysterol-binding protein-related protein 8 GN=OSBPL8 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 8 isoform X1 [Oryctolagus cuniculus]
ENSG00000091073(DTX2)	--	29.35949244	1464	31.31210061	1483	39.95004704	1871	38.51499604	1859	29.25085736	1427	49.32208473	2367	0.90654464	0.313486427	normal	0.981422828	-0.076879892	normal	0.898761918	0.330720524	normal	0.640838816	0.210480675	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K06058|0|hsa:113878|DTX2, RNF58; deltex 2, E3 ubiquitin ligase; K06058 deltex (A)"	Notch signaling pathway (ko04330)	--	--	"WWE domain;; Zinc finger, C3HC4 type (RING finger)"	Probable E3 ubiquitin-protein ligase DTX2 GN=DTX2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase DTX2 isoform X1 [Felis catus] 
ENSG00000091106(NLRC4)	--	0.11970658	8	0.130265714	5	0	0	0.044768446	3	0.0873548	5	0.08456541	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K12805|0|hsa:58484|NLRC4, AIFEC, CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, FCAS4, IPAF; NLR family, CARD domain containing 4; K12805 NLR family CARD domain-containing protein 4 (A)"	NOD-like receptor signaling pathway (ko04621);; Salmonella infection (ko05132);; Legionellosis (ko05134)	--	--	NACHT domain;; Caspase recruitment domain	NLR family CARD domain-containing protein 4 GN=UNQ6189/PRO20215 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: NLR family CARD domain-containing protein 4 [Galeopterus variegatus]
ENSG00000091127(PUS7)	--	13.838394	934	14.855889	995	14.81349	935	14.682532	989	13.938842	939	10.83155301	717	0.978066894	0.051633164	normal	0.974214585	-0.104833876	normal	0.743284666	-0.390561116	normal	0.543384551	-0.13691143	normal	[S]	Function unknown	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	K06176|0|ptr:472481|PUS7; pseudouridylate synthase 7 (putative); K06176 tRNA pseudouridine13 synthase [EC:5.4.99.27] (A)	--	[S]	Function unknown	tRNA pseudouridine synthase D (TruD)	Pseudouridylate synthase 7 homolog GN=PUS7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: pseudouridylate synthase 7 homolog [Tupaia chinensis] 
ENSG00000091128(LAMB4)	--	0.048382662	6	0.036092016	4	0.036525467	3	0.092334278	5	0.054901421	6	0.067665918	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06245|0|hsa:22798|LAMB4; laminin, beta 4; K06245 laminin, beta 4 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin N-terminal (Domain VI)	Laminin subunit beta-4 (Precursor) GN=LAMB4 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: laminin subunit beta-4 [Galeopterus variegatus]
ENSG00000091129(NRCAM)	--	20.81868034	2436	21.847041	2413	21.259883	2288	44.75920826	5032	41.40061828	4563	42.16405963	4833	1.11E-07	1.015330719	up	1.55E-05	0.897312614	normal	1.18E-08	1.070042641	up	1.81E-13	0.994031753	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06756|0|hsa:4897|NRCAM; neuronal cell adhesion molecule; K06756 neuronal cell adhesion molecule (A)	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Bravo-like intracellular region;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; CD47 immunoglobulin-like domain	Neuronal cell adhesion molecule (Precursor) GN=NRCAM OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neuronal cell adhesion molecule isoform X14 [Galeopterus variegatus]
ENSG00000091136(LAMB1)	--	92.50587	11047	86.892838	9937	91.014575	10144	97.142805	11143	94.732652	10976	104.052026	11741	0.996560314	-0.01834666	normal	0.994900158	0.122025884	normal	0.991679846	0.202609099	normal	0.689284357	0.100288286	normal	--	--	--	"K05636|0|hsa:3912|LAMB1, CLM, LIS5; laminin, beta 1; K05636 laminin, beta 1 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin N-terminal (Domain VI)	Laminin subunit beta-1 (Precursor) GN=LAMB1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: laminin subunit beta-1 [Tupaia chinensis]
ENSG00000091137(SLC26A4)	--	0.0385179	3	0.01268558	1	0	0	0.0127098	1	0	0	0.02551215	2	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14702|0|hsa:5172|SLC26A4, DFNB4, EVA, PDS, TDH2B; solute carrier family 26 (anion exchanger), member 4; K14702 solute carrier family 26 (sodium-independent chloride/iodide transporter), member 4 (A)"	Thyroid hormone synthesis (ko04918)	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; STAS domain;; Sulfate transporter N-terminal domain with GLY motif	Pendrin GN=SLC26A4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: pendrin [Balaenoptera acutorostrata scammoni]
ENSG00000091140(DLD)	--	72.32349149	2203	67.8466443	2249	71.3858602	2260	76.9390043	2554	84.38060267	2481	70.39110284	2179	0.977577551	0.182338584	normal	0.98419483	0.120134584	normal	0.986890161	-0.060906509	normal	0.721808438	0.082442147	normal	[C]	Energy production and conversion	Biological Process: tRNA processing (GO:0008033);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00382|0|hsa:1738|DLD, DLDD, DLDH, E3, GCSL, LAD, PHE3; dihydrolipoamide dehydrogenase (EC:1.8.1.4); K00382 dihydrolipoamide dehydrogenase [EC:1.8.1.4] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Glycine, serine and threonine metabolism (ko00260);; Valine, leucine and isoleucine degradation (ko00280);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200)"	[C]	Energy production and conversion	"Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain;; Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD dependent oxidoreductase;; FAD binding domain;; NAD(P)-binding Rossmann-like domain;; Glucose inhibited division protein A;; FAD binding domain;; Thi4 family"	"Dihydrolipoyl dehydrogenase, mitochondrial (Precursor) GN=DLD OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: dihydrolipoyl dehydrogenase, mitochondrial [Ailuropoda melanoleuca]"
ENSG00000091157(WDR7)	--	3.779170579	442	3.342669853	427	3.620200008	462	3.624580638	440	3.689405807	470	3.909096461	504	0.969917904	-0.037245347	normal	0.963339456	0.116604404	normal	0.96487073	0.116873062	normal	0.843140541	0.066617731	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 7 GN=WDR7 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 7 isoform X1 [Camelus ferus] 
ENSG00000091164(TXNL1)	--	35.90334162	1013	37.7247733	1050	33.477978	1019	35.74862606	1054	35.4707163	1070	29.184897	931	0.979672523	0.026369221	normal	0.979758218	0.005786655	normal	0.970910369	-0.138377488	normal	0.9074175	-0.034239609	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	PITH domain;; Thioredoxin	Thioredoxin-like protein 1 GN=TXNL1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	thioredoxin-like protein 1 [Sus scrofa] 
ENSG00000091262(ABCC6)	--	2.592432711	75	1.015982425	42	2.575659247	73	1.455103932	72	4.362976128	143	2.723474981	104	0.973145954	-0.087888134	normal	2.41E-07	1.710755271	up	0.858382869	0.493712873	normal	0.207603507	0.728068101	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05669|0|cjc:100387779|ABCC6; ATP-binding cassette, sub-family C (CFTR/MRP), member 6; K05669 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter;; ABC transporter transmembrane region;; AAA domain;; AAA ATPase domain;; AAA domain;; 50S ribosome-binding GTPase	Multidrug resistance-associated protein 6 GN=ABCC6 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: multidrug resistance-associated protein 6 [Vicugna pacos]
ENSG00000091317(CMTM6)	--	44.1475	1885	49.9075	2098	46.3331	1925	45.901	1963	41.7651	1786	44.2203	1924	0.986311034	0.027641308	normal	0.954267494	-0.25351085	normal	0.986511999	-0.00903399	normal	0.732946653	-0.079930135	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	CKLF-like MARVEL transmembrane domain-containing protein 6 GN=CMTM6 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: CKLF-like MARVEL transmembrane domain-containing protein 6 [Galeopterus variegatus]
ENSG00000091409(ITGA6)	--	30.512742	3021	26.850443	2615	30.00120803	2915	23.21297316	2305	17.17416733	1709	16.45746045	1547	0.720003323	-0.4208458	normal	0.032247781	-0.63462746	normal	4.56E-06	-0.921646565	normal	0.000415042	-0.643150897	normal	--	--	--	K06485|0|mcf:101925271|uncharacterized LOC101925271; K06485 integrin alpha 6 (A)	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Hematopoietic cell lineage (ko04640);; Regulation of actin cytoskeleton (ko04810);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Processed integrin alpha-6 (Precursor) GN=ITGA6 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: integrin alpha-6 isoform X1 [Myotis lucifugus]
ENSG00000091428(RAPGEF4)	--	0.832926736	33	0.648871691	29	0.607736209	45	0.194613593	16	0.471096026	39	0.222940331	16	0.839844447	-1.006558126	normal	0.970405783	0.388473545	normal	0.136128808	-1.417042975	normal	0.38714725	-0.611694652	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	K04351|0|mcf:101865166|uncharacterized LOC101865166; K04351 Rap guanine nucleotide exchange factor 4 (A)	Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Leukocyte transendothelial migration (ko04670);; Insulin secretion (ko04911)	[T]	Signal transduction mechanisms	"RasGEF domain;; Cyclic nucleotide-binding domain;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; RasGEF N-terminal motif;; Ras association (RalGDS/AF-6) domain"	Rap guanine nucleotide exchange factor 4 GN=RAPGEF4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rap guanine nucleotide exchange factor 4 isoform X1 [Elephantulus edwardii]
ENSG00000091436(MAP3K20)	--	36.89915238	4148	41.58342685	4709	39.49542457	4204	22.08653558	2442	20.23901341	2283	20.66204702	2123	0.000292783	-0.79479641	normal	2.65E-08	-1.065413791	down	2.67E-07	-0.993436863	normal	1.67E-12	-0.953241605	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04424|0|hsa:51776|ZAK, AZK, MLK7, MLT, MLTK, MRK, mlklak, pk; sterile alpha motif and leucine zipper containing kinase AZK (EC:2.7.11.25); K04424 sterile alpha motif and leucine zipper containing kinase AZK [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010);; Tight junction (ko04530)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Mitogen-activated protein kinase kinase kinase MLT GN=ZAK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase MLT isoform X1 [Galeopterus variegatus]
ENSG00000091483(FH)	--	47.1202	1458	42.3357	1319	48.5255	1497	55.1259	1721	56.0011	1722	44.504	1380	0.96498052	0.208221982	normal	0.837082477	0.362848969	normal	0.977970404	-0.12556524	normal	0.444885155	0.15272098	normal	[C]	Energy production and conversion	Biological Process: tricarboxylic acid cycle (GO:0006099);; Molecular Function: lyase activity (GO:0016829);; 	"K01679|0|hsa:2271|FH, HLRCC, LRCC, MCL, MCUL1; fumarate hydratase (EC:4.2.1.2); K01679 fumarate hydratase, class II [EC:4.2.1.2] (A)"	Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[C]	Energy production and conversion	Lyase;; Fumarase C C-terminus	"Fumarate hydratase, mitochondrial (Precursor) GN=FH OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: fumarate hydratase, mitochondrial [Camelus ferus] "
ENSG00000091490(SEL1L3)	--	19.16995974	1516	18.19167601	1420	18.4148553	1453	27.5485908	2165	27.2304901	2164	36.22749535	2898	0.421843244	0.482853608	normal	0.092337174	0.585874109	normal	4.34E-07	0.986989798	normal	0.002073549	0.699169023	normal	[R]	General function prediction only	--	--	--	[MOT]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Sel1 repeat	Protein sel-1 homolog 3 GN=SEL1L3 OS=Homo sapiens (Human) PE=1 SV=2	MOT	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	protein sel-1 homolog 3 [Bos taurus]
ENSG00000091513(TF)	--	0.055267027	3	0	0	0	0	0	0	0.130998689	7	0.35351617	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K14736|0|hsa:7018|TF, PRO1557, PRO2086, TFQTL1; transferrin; K14736 transferrin (A)"	HIF-1 signaling pathway (ko04066);; Mineral absorption (ko04978)	--	--	"Transferrin;; ABC transporter, phosphonate, periplasmic substrate-binding protein"	Serotransferrin (Precursor) GN=TF OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	serotransferrin precursor [Oryctolagus cuniculus] 
ENSG00000091527(CDV3)	--	48.225138	3015	53.380219	3195	48.33433868	3030	69.653857	4360	62.08983895	3685	62.595657	3818	0.405787987	0.501124446	normal	0.982271895	0.184340831	normal	0.927520183	0.32506303	normal	0.033538538	0.338793996	normal	--	--	--	--	--	--	--	Carnitine deficiency-associated protein 3	Protein CDV3 homolog GN=CDV3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein CDV3 homolog [Orcinus orca]
ENSG00000091536(MYO15A)	--	0.32200547	9	0.04413361	5	0.021323003	0	0.021935809	1	0.06364347	4	0.00783785	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoskeleton (GO:0005856);; Cellular Component: myosin complex (GO:0016459);; 	"K10361|0|hsa:51168|MYO15A, DFNB3, MYO15; myosin XVA; K10361 myosin XV (A)"	--	[N]	Cell motility	Myosin head (motor domain);; MyTH4 domain;; Variant SH3 domain;; FERM central domain;; IQ calmodulin-binding motif	Unconventional myosin-XV GN=MYO15A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-XV [Loxodonta africana]
ENSG00000091542(ALKBH5)	--	48.61077827	2295	49.00948155	2355	46.35317699	2242	49.097381	2332	45.10893405	2114	48.90456022	2333	0.988156785	-0.007753479	normal	0.977325194	-0.177058163	normal	0.987492419	0.049076135	normal	0.866334256	-0.04515171	normal	--	--	--	"K10767|0|pale:102880236|ALKBH5; alkB, alkylation repair homolog 5 (E. coli); K10767 alkylated DNA repair protein alkB homolog 5 [EC:1.14.11.-] (A)"	--	[S]	Function unknown	2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily	RNA demethylase ALKBH5 {ECO:0000303|PubMed:24616105} GN=ALKBH5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: RNA demethylase ALKBH5 isoform X1 [Equus przewalskii]
ENSG00000091583(APOH)	--	0.427745245	8	0.963799879	18	1.059224013	19	3.20665632	61	5.167252772	98	4.823336616	91	5.77E-07	2.685201543	up	7.72E-09	2.330058389	up	1.63E-07	2.165238554	up	2.37E-08	2.454553512	up	--	--	--	"K17305|0|hsa:350|APOH, B2G1, B2GP1, BG; apolipoprotein H (beta-2-glycoprotein I); K17305 beta-2-glycoprotein 1 (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Sushi domain (SCR repeat);; Beta-2-glycoprotein-1 fifth domain	Beta-2-glycoprotein 1 (Precursor) GN=APOH OS=Homo sapiens (Human) PE=1 SV=3	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: beta-2-glycoprotein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000091592(NLRP1)	--	0	0	0.026403969	3	0.02078025	1	0.187641029	13	0.147989634	16	0.117607468	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K12798|0|ptr:468451|NLRP1, NALP1; NLR family, pyrin domain containing 1; K12798 NACHT, LRR and PYD domains-containing protein 1 (A)"	NOD-like receptor signaling pathway (ko04621)	--	--	Function to find;; NACHT domain;; Caspase recruitment domain;; Leucine Rich repeat;; PAAD/DAPIN/Pyrin domain;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	"NACHT, LRR and PYD domains-containing protein 1 GN=NLRP1 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: NACHT, LRR and PYD domains-containing protein 1 [Vicugna pacos]"
ENSG00000091622(PITPNM3)	--	1.602987535	219	0.9010984	131	1.997244072	229	3.87831453	537	3.562274804	503	2.89173173	413	9.79E-09	1.257345878	up	0	1.907491065	up	0.002231594	0.838322091	normal	7.90E-09	1.306057717	up	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	DDHD domain;; LNS2 (Lipin/Ned1/Smp2)	Membrane-associated phosphatidylinositol transfer protein 3 GN=PITPNM3 OS=Homo sapiens (Human) PE=1 SV=2	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: membrane-associated phosphatidylinositol transfer protein 3 [Tupaia chinensis]
ENSG00000091640(SPAG7)	--	31.384256	683	30.777921	682	30.036602	674	28.89763	637	30.099743	650	29.016764	636	0.966411456	-0.131118951	normal	0.970601334	-0.090552873	normal	0.970956259	-0.09180119	normal	0.687790802	-0.105703939	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	R3H domain	Sperm-associated antigen 7 GN=SPAG7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: sperm-associated antigen 7 isoform 2 [Ceratotherium simum simum] 
ENSG00000091651(ORC6)	--	15.64060888	489	18.16422401	562	18.67793242	588	17.3597057	550	18.47564743	575	16.20503701	509	0.962411373	0.138354849	normal	0.972379855	0.011534583	normal	0.943574402	-0.215844724	normal	0.947730723	-0.025604186	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nuclear origin of replication recognition complex (GO:0005664);; Biological Process: DNA replication (GO:0006260);; 	"K02608|0|hsa:23594|ORC6, ORC6L; origin recognition complex, subunit 6; K02608 origin recognition complex subunit 6 (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	Origin recognition complex subunit 6 (ORC6)	Origin recognition complex subunit 6 GN=ORC6 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: origin recognition complex subunit 6 [Ceratotherium simum simum]
ENSG00000091656(ZFHX4)	--	1.019709236	285	1.518004848	260	0.954238532	279	1.169755274	343	1.298799271	387	1.213489537	358	0.933842642	0.235257066	normal	0.333010075	0.549758584	normal	0.848856856	0.349725458	normal	0.11957622	0.380015658	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K09380|0|hsa:79776|ZFHX4, ZFH4, ZHF4; zinc finger homeobox 4; K09380 zinc finger homeobox protein 4 (A)"	--	[R]	General function prediction only	"Homeobox domain;; Zinc finger, C2H2 type;; Homeobox KN domain;; Zinc-finger of C2H2 type"	Zinc finger homeobox protein 4 GN=ZFHX4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger homeobox protein 4 [Equus przewalskii]
ENSG00000091732(ZC3HC1)	--	10.5963447	372	12.16946245	430	12.14581136	424	10.97484216	379	13.03016963	452	12.43719944	438	0.96919119	-0.003920993	normal	0.968651164	0.05038671	normal	0.969778673	0.038440263	normal	0.946734065	0.029096743	normal	--	--	Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[S]	Function unknown	C3HC zinc finger-like;; Rsm1-like	Nuclear-interacting partner of ALK GN=ZC3HC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nuclear-interacting partner of ALK isoform X3 [Canis lupus familiaris]
ENSG00000091831(ESR1)	--	0.1886314	4	0.0806167	7	0.0345792	2	0.15888445	14	0.0960894	6	0.1914794	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: steroid binding (GO:0005496);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: estrogen receptor activity (GO:0030284);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08550|0|hsa:2099|ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1; estrogen receptor 1; K08550 estrogen receptor alpha (A)"	Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	"Oestrogen receptor;; Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor;; Oestrogen-type nuclear receptor final C-terminal"	Estrogen receptor GN=ESR1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: estrogen receptor [Odobenus rosmarus divergens]
ENSG00000091844(RGS17)	--	4.351005242	335	6.979946917	464	6.162090492	382	5.48695303	358	4.143777578	303	5.328854384	361	0.966755721	0.064679256	normal	0.090979125	-0.633657352	normal	0.965523615	-0.089500705	normal	0.38504904	-0.230002299	normal	--	--	--	K16449|6.93806e-143|ptr:737204|RGS17; regulator of G-protein signaling 17; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 17 GN=RGS17 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 17 [Galeopterus variegatus]
ENSG00000091879(ANGPT2)	--	0.053339652	5	0.010775699	1	0.096474202	8	0.060096984	5	0.061610407	5	0.066874991	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05466|0|mcf:101925495|uncharacterized LOC101925495; K05466 angiopoietin 2 (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; HIF-1 signaling pathway (ko04066);; PI3K-Akt signaling pathway (ko04151)	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-2 (Precursor) GN=ANGPT2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: angiopoietin-2 isoform X3 [Equus caballus] 
ENSG00000091947(TMEM101)	--	37.86997427	891	35.13099359	857	36.14876341	870	31.6668548	754	30.81028569	718	34.82346631	824	0.920875727	-0.271184098	normal	0.917355657	-0.276204627	normal	0.974584127	-0.086507969	normal	0.297472685	-0.210293771	normal	--	--	--	--	--	--	--	TMEM101 protein family	Transmembrane protein 101 GN=TMEM101 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 101 [Lipotes vexillifer]
ENSG00000091972(CD200)	--	0.037620922	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06556|0|hsa:4345|CD200, MOX1, MOX2, MRC, OX-2; CD200 molecule; K06556 CD200 antigen (A)"	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; CD80-like C2-set immunoglobulin domain	OX-2 membrane glycoprotein (Precursor) GN=CD200 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: OX-2 membrane glycoprotein isoform X3 [Galeopterus variegatus]
ENSG00000091986(CCDC80)	--	4.10453925	424	2.559478076	306	3.036041024	352	19.99853955	2491	29.93392051	3616	10.36564839	1286	0	2.519492801	up	0	3.534912549	up	0	1.856485093	up	0.001957958	2.750133362	up	--	--	--	--	--	--	--	Domain of unknown function (DUF4174)	Coiled-coil domain-containing protein 80 (Precursor) GN=CCDC80 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 80 [Odobenus rosmarus divergens]
ENSG00000092010(PSME1)	--	87.91033326	1629	82.48378175	1561	81.4846917	1534	112.5618826	2113	119.7701223	2189	106.0963325	1957	0.873918482	0.344188195	normal	0.526048687	0.465991979	normal	0.872723095	0.342753964	normal	0.012233493	0.384486636	normal	--	--	Cellular Component: proteasome activator complex (GO:0008537);; 	"K06696|1.85044e-144|pon:100455818|PSME1; proteasome (prosome, macropain) activator subunit 1 (PA28 alpha); K06696 proteasome activator subunit 1 (PA28 alpha) (A)"	Proteasome (ko03050);; Antigen processing and presentation (ko04612)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome activator pa28 beta subunit;; Proteasome activator pa28 alpha subunit	Proteasome activator complex subunit 1 GN=PSME1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome activator complex subunit 1 isoform X1 [Myotis lucifugus]
ENSG00000092020(PPP2R3C)	--	14.86979	417	13.003644	356	12.67138	337	16.002668	429	13.560642	397	13.089813	386	0.970118761	0.010061452	normal	0.959276462	0.135290793	normal	0.949670183	0.186777112	normal	0.740304548	0.105102458	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K11583|0|ptr:452859|PPP2R3C; protein phosphatase 2, regulatory subunit B'', gamma; K11583 serine/threonine-protein phosphatase 2A regulatory subunit B'' (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Dopaminergic synapse (ko04728)	[A]	RNA processing and modification	EF-hand domain pair	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma GN=PPP2R3C OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma [Vicugna pacos]
ENSG00000092036(HAUS4)	--	64.63310035	2956	60.3545748	3182	77.98886696	3712	91.60205783	4702	75.0841425	3773	94.976554	5011	0.027898923	0.638530711	normal	0.975814154	0.224253734	normal	0.763898032	0.424461013	normal	0.03701487	0.432508438	normal	--	--	Biological Process: spindle assembly (GO:0051225);; Cellular Component: HAUS complex (GO:0070652);; 	"K16587|0|hsa:54930|HAUS4, C14orf94; HAUS augmin-like complex, subunit 4; K16587 HAUS augmin-like complex subunit 4 (A)"	--	--	--	HAUS augmin-like complex subunit 4	HAUS augmin-like complex subunit 4 GN=HAUS4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: HAUS augmin-like complex subunit 4 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000092051(JPH4)	--	15.1558614	720	15.7285411	776	14.1767222	672	16.7467245	749	17.895901	897	20.9130341	974	0.975666685	0.02608198	normal	0.958435383	0.187285068	normal	0.246186326	0.526180071	normal	0.197138203	0.252620241	normal	--	--	--	--	--	[R]	General function prediction only	MORN repeat	Junctophilin-4 GN=JPH4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: junctophilin-4 [Leptonychotes weddellii]
ENSG00000092068(SLC7A8)	--	0.01439749	1	0.05300195	3	0.054239909	2	0.091588824	6	0.265650834	9	0.272948005	13	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13781|0|ptr:452793|SLC7A8; solute carrier family 7 (amino acid transporter light chain, L system), member 8; K13781 solute carrier family 7 (L-type amino acid transporter), member 8 (A)"	Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease	Large neutral amino acids transporter small subunit 2 GN=SLC7A8 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: large neutral amino acids transporter small subunit 2 isoform 1 [Equus caballus]
ENSG00000092094(OSGEP)	--	9.921281875	250	11.34776094	303	18.21729576	365	11.281277	325	9.376202043	284	10.506834	294	0.858819076	0.345810966	normal	0.960734597	-0.114264217	normal	0.880622101	-0.318896566	normal	0.913514069	-0.044828321	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K15900|0|ptr:473320|OSGEP; O-sialoglycoprotein endopeptidase; K01409 N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycoprotease family	Probable tRNA N6-adenosine threonylcarbamoyltransferase {ECO:0000255|HAMAP-Rule:MF_03180} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable tRNA N6-adenosine threonylcarbamoyltransferase isoform X1 [Ailuropoda melanoleuca] 
ENSG00000092096(SLC22A17)	--	9.817007	269	9.60284408	288	8.37918672	247	6.34145714	147	9.075179132	260	6.770642008	189	0.003294838	-0.895591109	normal	0.952419024	-0.168054489	normal	0.826102409	-0.39166644	normal	0.135917219	-0.452416769	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08213|0|myb:102238958|SLC22A17; solute carrier family 22, member 17; K08213 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 17 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 17 GN=SLC22A17 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 22 member 17 [Myotis brandtii]
ENSG00000092098(RNF31)	--	14.51471707	817	11.06458378	622	12.66104048	692	14.19870616	753	12.78570828	739	11.56197482	665	0.966085555	-0.148227998	normal	0.941863947	0.226726987	normal	0.973285561	-0.065562967	normal	0.996289322	-0.004053901	normal	--	--	--	"K11974|0|hsa:55072|RNF31, HOIP, ZIBRA; ring finger protein 31; K11974 E3 ubiquitin-protein ligase RNF31 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	PUB domain;; IBR domain	E3 ubiquitin-protein ligase RNF31 GN=RNF31 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF31 isoform X2 [Ursus maritimus]
ENSG00000092108(SCFD1)	--	14.39227649	503	14.97221932	546	14.44820326	523	18.82365928	699	19.0437406	679	19.2896133	708	0.588731788	0.442750087	normal	0.900387339	0.292356708	normal	0.639873826	0.427580445	normal	0.038531657	0.386953038	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec1 family	Sec1 family domain-containing protein 1 GN=SCFD1 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sec1 family domain-containing protein 1 isoform X2 [Mustela putorius furo] 
ENSG00000092140(G2E3)	--	10.26449555	688	9.399746628	591	12.9129706	777	11.77693878	799	9.6631484	682	9.62911932	638	0.957473256	0.184571941	normal	0.954782472	0.184746688	normal	0.901884566	-0.292021316	normal	0.95437657	0.022025198	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	--	--	[K]	Transcription	PHD-like zinc-binding domain;; HECT-domain (ubiquitin-transferase);; PHD-zinc-finger like domain	G2/M phase-specific E3 ubiquitin-protein ligase GN=G2E3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: G2/M phase-specific E3 ubiquitin-protein ligase [Odobenus rosmarus divergens]
ENSG00000092148(HECTD1)	--	27.80222731	4438	30.07991793	4890	28.41610715	4498	27.95030839	4117	25.99985907	4111	31.38329922	4890	0.988941155	-0.139098466	normal	0.9681232	-0.271679883	normal	0.991009469	0.112223166	normal	0.674044254	-0.096610266	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: metal ion binding (GO:0046872);; 	K12231|0|pps:100994760|HECTD1; HECT domain containing E3 ubiquitin protein ligase 1; K12231 E3 ubiquitin-protein ligase HECTD1 [EC:6.3.2.19] (A)	--	[R]	General function prediction only	HECT-domain (ubiquitin-transferase);; Sad1 / UNC-like C-terminal;; Mib_herc2;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; F5/8 type C domain	E3 ubiquitin-protein ligase HECTD1 GN=HECTD1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase HECTD1 [Camelus ferus] 
ENSG00000092199(HNRNPC)	--	340.431357	10267	335.1557487	10364	358.5781912	10912	388.161216	12044	391.8505837	11794	350.5663347	10740	0.992088802	0.199440082	normal	0.993732358	0.165023036	normal	0.996408038	-0.031208638	normal	0.647474419	0.111121206	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12884|8.7367e-133|pon:100172712|HNRNPC, HNRPC; heterogeneous nuclear ribonucleoprotein C (C1/C2); K12884 heterogeneous nuclear ribonucleoprotein C1/C2 (A)"	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoproteins C1/C2 GN=HNRNPC OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein C-like isoform X1 [Lipotes vexillifer]
ENSG00000092200(RPGRIP1)	--	0.341409174	7	0.25742815	16	0.100662019	6	0.309211566	10	0.601082613	11	0.886570275	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16512|0|hsa:57096|RPGRIP1, CORD13, LCA6, RGI1, RGRIP, RPGRIP, RPGRIP1d; retinitis pigmentosa GTPase regulator interacting protein 1; K16512 X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (A)"	--	--	--	Protein of unknown function (DUF3250)	X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 GN=RPGRIP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 [Ceratotherium simum simum]
ENSG00000092201(SUPT16H)	--	50.003291	4935	50.73431	4974	52.798353	5211	56.682277	5637	58.806041	5806	48.247147	4730	0.98923319	0.160998297	normal	0.985480687	0.201654714	normal	0.989579948	-0.147966422	normal	0.758315786	0.075577389	normal	[KLB]	"Transcription;; Replication, recombination and repair;; Chromatin structure and dynamics"	--	--	--	[E]	Amino acid transport and metabolism	FACT complex subunit (SPT16/CDC68);; FACT complex subunit SPT16 N-terminal lobe domain;; Metallopeptidase family M24;; Histone chaperone Rttp106-like	FACT complex subunit SPT16 GN=SUPT16H OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: FACT complex subunit SPT16 [Pteropus alecto] 
ENSG00000092203(TOX4)	--	16.34930861	1249	15.81823147	1293	16.82803226	1280	16.00864482	1299	16.96455748	1325	15.73662617	1282	0.982068885	0.025764613	normal	0.982117168	0.013827551	normal	0.982387825	-0.006031869	normal	0.978166038	0.010158288	normal	--	--	--	--	--	[R]	General function prediction only	HMG (high mobility group) box;; HMG-box domain	TOX high mobility group box family member 4 GN=TOX4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: TOX high mobility group box family member 4 isoform 1 [Trichechus manatus latirostris]
ENSG00000092208(GEMIN2)	--	9.530120197	174	9.398192982	188	8.14063774	156	10.57592601	200	9.596088325	203	10.199007	179	0.955442417	0.168690318	normal	0.96282776	0.088634283	normal	0.953324621	0.188415759	normal	0.726808553	0.146310232	normal	--	--	--	K13130|0|pps:100967993|GEMIN2; gem (nuclear organelle) associated protein 2; K13130 survival of motor neuron protein-interacting protein 1 (A)	RNA transport (ko03013)	--	--	Survival motor neuron (SMN) interacting protein 1 (SIP1)	Gem-associated protein 2 GN=GEMIN2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: gem-associated protein 2 isoformX1 [Equus caballus] 
ENSG00000092295(TGM1)	--	0.673326551	30	1.401966948	36	1.269191713	47	0.386920055	15	0.241654734	17	0.664905327	18	0.892680195	-0.960018868	normal	0.765145298	-1.038999663	normal	0.188804246	-1.321808165	normal	0.038613332	-1.196310656	normal	--	--	Molecular Function: protein-glutamine gamma-glutamyltransferase activity (GO:0003810);; Biological Process: peptide cross-linking (GO:0018149);; 	"K05619|0|hsa:7051|TGM1, ARCI1, ICR2, KTG, LI, LI1, TGASE, TGK; transglutaminase 1 (EC:2.3.2.13); K05619 transglutaminase 1 [EC:2.3.2.13] (A)"	--	--	--	"Transglutaminase family, C-terminal ig like domain;; Transglutaminase family;; Transglutaminase-like superfamily"	Protein-glutamine gamma-glutamyltransferase K GN=TGM1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-glutamine gamma-glutamyltransferase K [Tupaia chinensis] 
ENSG00000092330(TINF2)	--	18.32536553	677	16.8938962	632	15.09430559	585	14.43934028	537	12.88225562	488	16.4354258	604	0.802564965	-0.364135681	normal	0.748139304	-0.393395413	normal	0.973043669	0.037724505	normal	0.268816438	-0.238514964	normal	--	--	--	"K11112|0|hsa:26277|TINF2, DKCA3, TIN2; TERF1 (TRF1)-interacting nuclear factor 2; K11112 TERF1-interacting nuclear factor 2 (A)"	--	--	--	TERF1-interacting nuclear factor 2 N-terminus	TERF1-interacting nuclear factor 2 GN=TINF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TERF1-interacting nuclear factor 2 [Galeopterus variegatus]
ENSG00000092421(SEMA6A)	--	0.086711697	7	0.090702766	4	0.105558715	7	0.115356327	6	0.178707485	12	0.314911956	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06842|0|hsa:57556|SEMA6A, HT018, SEMA, SEMA6A1, SEMAQ, VIA; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; K06842 semaphorin 6 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-6A (Precursor) GN=SEMA6A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: semaphorin-6A isoform 1 [Ceratotherium simum simum]
ENSG00000092439(TRPM7)	--	19.4874143	2244	21.83394825	2539	20.14039418	2327	18.7345272	2220	17.70412618	2169	25.22777319	3092	0.987336581	-0.046313381	normal	0.961071137	-0.248496568	normal	0.782189783	0.401550546	normal	0.901973769	0.053093124	normal	--	--	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein tetramerization (GO:0051262);; Biological Process: transmembrane transport (GO:0055085);; 	"K04982|0|pps:100982703|TRPM7; transient receptor potential cation channel, subfamily M, member 7; K04982 transient receptor potential cation channel subfamily M member 7 [EC:2.7.11.1] (A)"	Mineral absorption (ko04978)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Alpha-kinase family;; Ion transport protein	Transient receptor potential cation channel subfamily M member 7 GN=TRPM7 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily M member 7 isoformX1 [Canis lupus familiaris]
ENSG00000092445(TYRO3)	--	3.920696578	412	3.473868211	348	3.586211826	374	4.4048638	458	4.3780376	436	3.296646	331	0.963156798	0.121441347	normal	0.891381045	0.302637184	normal	0.950365267	-0.183708353	normal	0.78659429	0.08928364	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05116|0|hsa:7301|TYRO3, BYK, Dtk, Etk-2, RSE, Rek, Sky, Tif; TYRO3 protein tyrosine kinase (EC:2.7.10.1); K05116 TYRO3 protein tyrosine kinase 3 [EC:2.7.10.1] (A)"	--	--	--	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Tyrosine-protein kinase receptor TYRO3 (Precursor) GN=TYRO3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase receptor TYRO3 isoform X1 [Galeopterus variegatus]
ENSG00000092470(WDR76)	--	9.883108085	530	9.936403167	555	12.35196122	623	9.624851382	501	11.01513538	542	7.308270646	383	0.966045651	-0.111680952	normal	0.970680604	-0.055468527	normal	0.012914604	-0.707965352	normal	0.189565437	-0.281928686	normal	--	--	--	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 76 GN=WDR76 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 76 isoform X1 [Sus scrofa]
ENSG00000092529(CAPN3)	--	0.229774883	7	0.345364251	7	0.207864843	5	0.135456547	5	0.287272618	7	0.227359003	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K08573|0|hsa:825|CAPN3, CANP3, CANPL3, LGMD2, LGMD2A, nCL-1, p94; calpain 3, (p94) (EC:3.4.22.54); K08573 calpain-3 [EC:3.4.22.54] (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF-hand domain pair;; EF hand"	Calpain-3 GN=CAPN3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calpain-3 isoform X1 [Vicugna pacos]
ENSG00000092531(SNAP23)	--	14.1190403	548	11.62252388	488	14.32929492	536	17.237237	677	16.97731279	635	16.369263	619	0.914273437	0.273456871	normal	0.820348253	0.357475281	normal	0.949986006	0.198892369	normal	0.18416393	0.275362478	normal	--	--	--	"K08508|2.05679e-152|pps:100982330|SNAP23; synaptosomal-associated protein, 23kDa; K08508 synaptosomal-associated protein 23 (A)"	SNARE interactions in vesicular transport (ko04130);; Platelet activation (ko04611)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain;; SNAP-25 family	Synaptosomal-associated protein 23 GN=SNAP23 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptosomal-associated protein 23 isoform X3 [Tupaia chinensis]
ENSG00000092607(TBX15)	--	0.042774373	3	0.019302628	1	0	0	0.019367422	1	0.018693928	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10182|0|mcf:102140955|TBX15; T-box 15; K10182 T-box protein 15 (A)	--	[K]	Transcription	T-box	T-box transcription factor TBX15 GN=TBX15 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: T-box transcription factor TBX15 [Galeopterus variegatus]
ENSG00000092621(PHGDH)	--	46.23960032	1739	43.401235	1680	41.6032637	1599	15.62610026	589	15.26960025	566	34.52550025	1294	0	-1.59021251	down	0	-1.588424158	down	0.901422702	-0.313293739	normal	0.002051774	-1.05380722	down	[HE]	Coenzyme transport and metabolism;; Amino acid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00058|0|pps:100985690|PHGDH; phosphoglycerate dehydrogenase; K00058 D-3-phosphoglycerate dehydrogenase [EC:1.1.1.95] (A)	"Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	"D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain"	D-3-phosphoglycerate dehydrogenase GN=PHGDH OS=Homo sapiens (Human) PE=1 SV=4	E	Amino acid transport and metabolism	PREDICTED: D-3-phosphoglycerate dehydrogenase [Ailuropoda melanoleuca] 
ENSG00000092758(COL9A3)	--	0.129424189	7	0.034910828	2	0.066701261	3	0.036538992	2	0.055371773	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08131|1.95567e-120|ggo:101138226|COL9A3; collagen alpha-3(IX) chain; K08131 collagen, type IX, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	Collagen alpha-3(IX) chain (Precursor) GN=COL9A3 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-3(IX) chain [Tupaia chinensis]
ENSG00000092820(EZR)	--	96.92698211	6464	96.64504281	6667	104.2231361	6957	144.4704116	9754	115.6419746	7639	105.0996564	6972	0.222612	0.562624957	normal	0.990477142	0.174882426	normal	0.994944668	-0.005183068	normal	0.271331944	0.256298573	normal	--	--	--	K08007|0|pps:100983688|EZR; ezrin; K08007 villin 2 (ezrin) (A)	Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Gastric acid secretion (ko04971);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	[R]	General function prediction only	Ezrin/radixin/moesin family;; FERM C-terminal PH-like domain;; FERM central domain;; FERM N-terminal domain	Ezrin GN=EZR OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: ezrin [Felis catus]
ENSG00000092841(MYL6)	--	687.799225	6829	820.9923711	8290	753.911127	7620	1319.591887	13331	1182.035283	11438	1095.597418	10784	3.29E-06	0.934053457	normal	0.818734468	0.442895194	normal	0.594273625	0.492655469	normal	5.93E-05	0.622908883	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K12751|5.30332e-136|mcf:102120485|MYL6; myosin, light chain 6, alkali, smooth muscle and non-muscle; K12751 myosin light chain 6 (A)"	Vascular smooth muscle contraction (ko04270);; Oxytocin signaling pathway (ko04921)	[Z]	Cytoskeleton	EF-hand domain;; EF hand;; EF-hand domain pair	Myosin light polypeptide 6 GN=MYL6 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: myosin light polypeptide 6 [Dasypus novemcinctus]
ENSG00000092847(AGO1)	--	5.038462049	989	5.240866525	1031	5.54818034	1045	4.857544493	1035	4.474684618	959	4.035754196	824	0.979237085	0.034703377	normal	0.97239021	-0.125676975	normal	0.833178827	-0.350505513	normal	0.513298746	-0.143018231	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	K11593|0|tup:102484879|AGO1; argonaute RISC catalytic component 1; K11593 eukaryotic translation initiation factor 2C (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Piwi domain;; PAZ domain;; Domain of unknown function (DUF1785)	Protein argonaute-1 GN=AGO1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	protein argonaute-1 [Sus scrofa] 
ENSG00000092850(TEKT2)	--	0.0293483	1	0	0	0.0281112	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18629|0|hsa:27285|TEKT2, TEKTB1, TEKTIN-T, h-tektin-t; tektin 2 (testicular); K18629 tektin-2 (A)"	--	[Z]	Cytoskeleton	Tektin family	Tektin-2 GN=TEKT2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tektin-2 [Capra hircus]
ENSG00000092853(CLSPN)	--	6.0324896	664	6.714739836	743	8.2084158	894	6.59561281	735	6.50971454	716	4.981936309	553	0.969201848	0.115474719	normal	0.97294993	-0.074674338	normal	0.009185055	-0.699766932	normal	0.42829059	-0.220919174	normal	--	--	--	--	--	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	--	Claspin GN=CLSPN OS=Homo sapiens (Human) PE=1 SV=3	DT	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	PREDICTED: claspin isoform X1 [Galeopterus variegatus]
ENSG00000092871(RFFL)	--	28.88214884	2046	29.5610061	2107	32.50997221	2091	27.92059583	2045	30.79034755	2165	27.83908532	2156	0.986829993	-0.031513895	normal	0.987059536	0.017737594	normal	0.987105521	0.035847141	normal	0.98564369	0.006913316	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Degradation arginine-rich protein for mis-folding;; SAP domain"	E3 ubiquitin-protein ligase rififylin {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase rififylin isoform X2 [Tupaia chinensis]
ENSG00000092929(UNC13D)	--	1.916523851	84	1.439811399	92	1.007488224	89	3.471162	307	3.931437996	341	2.722327383	235	2.13E-13	1.820350771	up	2.38E-14	1.851721869	up	4.44E-07	1.377533898	up	7.05E-11	1.714608544	up	--	--	--	--	--	[UT]	"Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	C2 domain;; Munc13 (mammalian uncoordinated) homology domain	Protein unc-13 homolog D GN=UNC13D OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein unc-13 homolog D [Ceratotherium simum simum]
ENSG00000092931(MFSD11)	--	73.73707216	1334	70.29999292	1329	63.61496038	1234	84.44466152	1434	85.69347623	1391	88.74766449	1555	0.981390661	0.07337258	normal	0.981963916	0.044305477	normal	0.886493136	0.324925267	normal	0.472772928	0.147466793	normal	--	--	--	--	--	[S]	Function unknown	Ion channel regulatory protein UNC-93;; Major Facilitator Superfamily	UNC93-like protein MFSD11 GN=MFSD11 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: UNC93-like protein MFSD11 isoform 1 [Ceratotherium simum simum]
ENSG00000092964(DPYSL2)	--	53.52363343	4326	59.18664774	4787	60.3235088	4862	56.25346601	4508	42.523468	3426	60.94157244	4911	0.992633988	0.028611632	normal	0.437253651	-0.503834113	normal	0.993283944	0.006173576	normal	0.589171473	-0.142590971	normal	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K07528|0|hsa:1808|DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2; dihydropyrimidinase-like 2; K07528 dihydropyrimidinase-like 2 (A)"	Axon guidance (ko04360)	[F]	Nucleotide transport and metabolism	Amidohydrolase family;; Amidohydrolase;; Amidohydrolase;; Amidohydrolase family	Dihydropyrimidinase-related protein 2 GN=DPYSL2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: dihydropyrimidinase-related protein 2 isoformX2 [Sus scrofa]
ENSG00000092969(TGFB2)	--	34.717366	1953	46.81162	2774	43.365554	2434	76.335378	4362	66.721685	3771	67.51282925	3804	1.09E-09	1.12785663	up	0.756634892	0.421355093	normal	0.02798303	0.635578196	normal	3.39E-06	0.715535834	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K13376|0|ptr:457742|TGFB2; transforming growth factor, beta 2; K13376 transforming growth factor beta-2 (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350);; Osteoclast differentiation (ko04380);; Hippo signaling pathway (ko04390);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Malaria (ko05144);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Chronic myeloid leukemia (ko05220);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Latency-associated peptide (Precursor) GN=TGFB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: transforming growth factor beta-2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000092978(GPATCH2)	--	7.188874205	430	8.704673	496	7.670863	393	6.446490813	430	8.102546	459	6.651304	375	0.969890481	-0.03072249	normal	0.961751503	-0.132851318	normal	0.966866245	-0.075632186	normal	0.799428021	-0.083281229	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K17569|0|ptr:457739|GPATCH2, GPATC2; G patch domain containing 2; K17569 G patch domain-containing protein 2 (A)"	--	[R]	General function prediction only	G-patch domain;; DExH-box splicing factor binding site	G patch domain-containing protein 2 GN=GPATCH2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: G patch domain-containing protein 2 [Ceratotherium simum simum]
ENSG00000093000(NUP50)	--	19.80265388	1233	16.44317702	1248	16.03392929	1176	17.5563955	1394	18.7019331	1406	19.21641298	1374	0.97411722	0.146054264	normal	0.973364377	0.150380347	normal	0.958288637	0.215945353	normal	0.388850054	0.16945208	normal	--	--	Cellular Component: nuclear pore (GO:0005643);; Biological Process: intracellular transport (GO:0046907);; 	"K14295|0|hsa:10762|NUP50, NPAP60, NPAP60L; nucleoporin 50kDa; K14295 nuclear pore complex protein Nup50 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	NUP50 (Nucleoporin 50 kDa);; RanBP1 domain	Nuclear pore complex protein Nup50 GN=NUP50 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: nuclear pore complex protein Nup50 isoform X2 [Tupaia chinensis]
ENSG00000093009(CDC45)	--	10.6585496	407	12.79970053	496	13.85327975	528	13.33888571	415	10.70235852	398	10.3117956	390	0.969914822	-0.00273948	normal	0.852368102	-0.337845721	normal	0.612845994	-0.443870163	normal	0.241675918	-0.271519818	normal	--	--	Biological Process: DNA replication initiation (GO:0006270);; 	"K06628|0|hsa:8318|CDC45, CDC45L, CDC45L2, PORC-PI-1; cell division cycle 45; K06628 cell division control protein 45 (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	CDC45-like protein	Cell division control protein 45 homolog GN=CDC45 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: cell division control protein 45 homolog isoform X1 [Felis catus] 
ENSG00000093010(COMT)	--	46.412339	1289	51.372975	1376	47.513007	1361	60.439097	1596	59.247237	1553	55.770384	1437	0.93201129	0.277078869	normal	0.974487763	0.152992458	normal	0.981732433	0.070025821	normal	0.39482408	0.166423052	normal	[R]	General function prediction only	Molecular Function: O-methyltransferase activity (GO:0008171);; 	"K00545|0|hsa:1312|COMT, HEL-S-98n; catechol-O-methyltransferase (EC:2.1.1.6); K00545 catechol O-methyltransferase [EC:2.1.1.6] (A)"	Steroid hormone biosynthesis (ko00140);; Tyrosine metabolism (ko00350);; Dopaminergic synapse (ko04728)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	O-methyltransferase;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain	Catechol O-methyltransferase GN=COMT OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: catechol O-methyltransferase isoform X2 [Myotis brandtii] 
ENSG00000093072(CECR1)	--	0.020509647	1	0	0	0	0	0.020613683	1	0.019980484	0	0.040766186	2	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	Cellular Component: extracellular space (GO:0005615);; Molecular Function: deaminase activity (GO:0019239);; 	--	--	[F]	Nucleotide transport and metabolism	Adenosine/AMP deaminase;; Adenosine/AMP deaminase N-terminal	Adenosine deaminase CECR1 (Precursor) GN=CECR1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: adenosine deaminase CECR1 isoform X1 [Felis catus] 
ENSG00000093134(VNN3)	--	0.048847196	1	0	0	0	0	0.102990703	3	0.063069153	1	0.294017758	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; "	K08069|2.30333e-166|ggo:101126064|vascular non-inflammatory molecule 3-like; K08069 pantetheine hydrolase [EC:3.5.1.92] (A)	Pantothenate and CoA biosynthesis (ko00770)	[E]	Amino acid transport and metabolism	Carbon-nitrogen hydrolase	Vascular non-inflammatory molecule 3 (Precursor) GN=VNN3 OS=Homo sapiens (Human) PE=2 SV=2	E	Amino acid transport and metabolism	PREDICTED: vascular non-inflammatory molecule 3 [Oryctolagus cuniculus]
ENSG00000093144(ECHDC1)	--	31.50538206	923	32.10175656	1076	28.95114172	968	34.49948765	1045	32.88978906	937	37.5279141	1165	0.969453984	0.148036439	normal	0.951673008	-0.220651041	normal	0.935355119	0.258590815	normal	0.810300485	0.063968019	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	K18426|0|pps:100992035|ECHDC1; enoyl CoA hydratase domain containing 1; K18426 ethylmalonyl-CoA/methylmalonyl-CoA decarboxylase [EC:4.1.1.94 4.1.1.41] (A)	Propanoate metabolism (ko00640)	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family	Ethylmalonyl-CoA decarboxylase GN=ECHDC1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: ethylmalonyl-CoA decarboxylase isoform X1 [Panthera tigris altaica] 
ENSG00000093167(LRRFIP2)	--	16.45425828	826	18.52775869	933	19.16466958	919	25.09893199	1250	21.50411672	1060	21.75008721	1078	0.121999872	0.566020811	normal	0.966841155	0.162441573	normal	0.951238617	0.221591956	normal	0.062984991	0.31763609	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	Double stranded RNA binding protein (DUF2051)	Leucine-rich repeat flightless-interacting protein 2 GN=LRRFIP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat flightless-interacting protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000093183(SEC22C)	--	19.284968	1000	22.0950112	1153	20.34650201	940	18.676986	995	17.03897906	965	17.31361008	931	0.9789831	-0.038005293	normal	0.923545206	-0.27781931	normal	0.978663428	-0.022135248	normal	0.601492541	-0.11909276	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K08520|0|pps:100978427|SEC22C; SEC22 vesicle trafficking protein homolog C (S. cerevisiae); K08520 SEC22 vesicle trafficking protein A/C (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Regulated-SNARE-like domain	Vesicle-trafficking protein SEC22c GN=SEC22C OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-trafficking protein SEC22c isoform 1 [Ceratotherium simum simum] 
ENSG00000093217(XYLB)	--	4.8018	553	4.2850121	490	4.7917	497	3.230953	395	3.0883617	328	2.8669892	343	0.350288629	-0.514558596	normal	0.145526616	-0.598239644	normal	0.283671346	-0.541334292	normal	0.004552243	-0.5524718	normal	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K00854|0|hsa:9942|XYLB; xylulokinase homolog (H. influenzae) (EC:2.7.1.17); K00854 xylulokinase [EC:2.7.1.17] (A)	Pentose and glucuronate interconversions (ko00040)	[G]	Carbohydrate transport and metabolism	"FGGY family of carbohydrate kinases, C-terminal domain;; FGGY family of carbohydrate kinases, N-terminal domain"	Xylulose kinase GN=XYLB OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: xylulose kinase isoform 1 [Ceratotherium simum simum]
ENSG00000094631(HDAC6)	--	18.58462824	1123	17.1136927	1029	17.62624839	1105	9.103263884	616	12.69941255	817	10.56931831	775	3.28E-05	-0.89550704	normal	0.831914318	-0.353676769	normal	0.262797096	-0.519216514	normal	0.000148683	-0.581180075	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: zinc ion binding (GO:0008270);; 	"K11407|0|hsa:10013|HDAC6, CPBHM, HD6, PPP1R90; histone deacetylase 6 (EC:3.5.1.98); K11407 histone deacetylase 6 [EC:3.5.1.98] (A)"	Alcoholism (ko05034);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain;; Zn-finger in ubiquitin-hydrolases and other protein	Histone deacetylase 6 GN=HDAC6 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 6 [Ceratotherium simum simum]
ENSG00000094804(CDC6)	--	22.05445766	1770	23.85182282	1857	29.43513402	2112	22.73728382	1765	21.71673388	1724	19.305388	1461	0.985364373	-0.034883118	normal	0.98018898	-0.12853193	normal	0.190446915	-0.539477943	normal	0.178459022	-0.234815265	normal	[LO]	"Replication, recombination and repair;; Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K02213|0|hsa:990|CDC6, CDC18L, HsCDC18, HsCDC6; cell division cycle 6; K02213 cell division control protein 6 (A)"	Cell cycle (ko04110)	[LD]	"Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	"AAA domain;; AAA ATPase domain;; ATPase family associated with various cellular activities (AAA);; CDC6, C terminal;; NACHT domain"	Cell division control protein 6 homolog GN=CDC6 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: cell division control protein 6 homolog [Ceratotherium simum simum]
ENSG00000094841(UPRT)	--	9.670254233	233	7.205240167	228	9.38118	233	7.656055841	248	7.517678474	227	9.205412897	273	0.965673415	0.058802047	normal	0.965593017	-0.027584719	normal	0.941393089	0.218965341	normal	0.833604957	0.087181395	normal	[F]	Nucleotide transport and metabolism	--	"K00761|0|hsa:139596|UPRT, FUR1, UPP; uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae) (EC:2.4.2.9); K00761 uracil phosphoribosyltransferase [EC:2.4.2.9] (A)"	Pyrimidine metabolism (ko00240)	[R]	General function prediction only	Uracil phosphoribosyltransferase	Uracil phosphoribosyltransferase homolog GN=UPRT OS=Homo sapiens (Human) PE=2 SV=1	F	Nucleotide transport and metabolism	PREDICTED: uracil phosphoribosyltransferase homolog [Galeopterus variegatus]
ENSG00000094880(CDC23)	--	20.572464	885	21.10665	943	20.728	879	21.02065	1043	22.81301	1079	19.99827	873	0.955799486	0.205828105	normal	0.965065675	0.172679597	normal	0.977958902	-0.018141634	normal	0.581825633	0.124133584	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: anaphase-promoting complex (GO:0005680);; Biological Process: regulation of mitotic metaphase/anaphase transition (GO:0030071);; 	K03355|0|ptr:462092|CDC23; cell division cycle 23; K03355 anaphase-promoting complex subunit 8 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"Anaphase promoting complex subunit 8 / Cdc23;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Transposase domain (DUF772)"	Cell division cycle protein 23 homolog GN=CDC23 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cell division cycle protein 23 homolog isoform X1 [Galeopterus variegatus]
ENSG00000094914(AAAS)	--	36.555111	1100	38.53012	1140	34.455649	1064	34.27965701	991	34.58836404	1025	31.809697	958	0.964042463	-0.181112138	normal	0.965852637	-0.174592074	normal	0.968057597	-0.159453067	normal	0.392395386	-0.173168587	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14320|0|ptr:467003|AAAS, aladin; achalasia, adrenocortical insufficiency, alacrimia; K14320 aladin (A)"	RNA transport (ko03013)	[R]	General function prediction only	"WD domain, G-beta repeat"	Aladin GN=AAAS OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: aladin [Tupaia chinensis]
ENSG00000094916(CBX5)	--	34.65133	5885	37.921449	6672	36.996086	6239	39.05629204	7013	34.614142	6062	36.0456	6446	0.985015272	0.22210388	normal	0.990594009	-0.159713997	normal	0.994375742	0.038788687	normal	0.90801502	0.033061732	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	K11587|6.22223e-128|ssc:102158072|chromobox protein homolog 5-like; K11587 chromobox protein 5 (A)	--	[B]	Chromatin structure and dynamics	Chromo shadow domain;; Chromo (CHRromatin Organisation MOdifier) domain	Chromobox protein homolog 5 GN=CBX5 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: chromobox protein homolog 5 isoform X1 [Tupaia chinensis]
ENSG00000094975(SUCO)	--	8.97932363	898	8.441574655	837	8.355224552	812	11.19722456	1105	10.40973012	1033	11.89845892	1180	0.927652401	0.268012792	normal	0.917390522	0.281655374	normal	0.223178698	0.530120161	normal	0.031112833	0.36038637	normal	--	--	--	--	--	[S]	Function unknown	Sad1 / UNC-like C-terminal	SUN domain-containing ossification factor (Precursor) GN=SUCO OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: SUN domain-containing ossification factor isoform 2 [Trichechus manatus latirostris]
ENSG00000095002(MSH2)	--	28.18992808	1741	27.897547	1725	30.446959	1859	25.277914	1569	23.32527997	1434	18.92319511	1167	0.972081241	-0.180734995	normal	0.928971877	-0.28770081	normal	0.008968008	-0.67930972	normal	0.016291317	-0.374650085	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	"K08735|0|hsa:4436|MSH2, COCA1, FCC1, HNPCC, HNPCC1, LCFS2; mutS homolog 2; K08735 DNA mismatch repair protein MSH2 (A)"	Mismatch repair (ko03430);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210)	[L]	"Replication, recombination and repair"	MutS domain V;; MutS domain III;; MutS domain II;; MutS domain I;; MutS family domain IV	DNA mismatch repair protein Msh2 GN=MSH2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA mismatch repair protein Msh2 [Equus przewalskii]
ENSG00000095015(MAP3K1)	--	1.67111536	205	1.54839251	190	1.715229956	208	3.400754	416	3.7338372	459	3.716686374	458	8.14E-05	0.984844775	normal	6.41E-08	1.244495902	up	1.27E-06	1.124820705	up	1.43E-08	1.123684886	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04416|0|hsa:4214|MAP3K1, MAPKKK1, MEKK, MEKK_1, MEKK1, SRXY6; mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase (EC:2.7.11.25); K04416 mitogen-activated protein kinase kinase kinase 1 [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010);; Ubiquitin mediated proteolysis (ko04120);; RIG-I-like receptor signaling pathway (ko04622);; Neurotrophin signaling pathway (ko04722);; GnRH signaling pathway (ko04912);; Hepatitis B (ko05161);; HTLV-I infection (ko05166)	--	--	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Mitogen-activated protein kinase kinase kinase 1 GN=MAP3K1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 1 [Sus scrofa]
ENSG00000095059(DHPS)	--	29.02326598	645	25.16713984	570	27.58344432	634	19.3660978	435	18.27148049	418	22.20696587	524	0.101012429	-0.597370925	normal	0.53409934	-0.467431037	normal	0.907338585	-0.282465168	normal	0.017911522	-0.445773059	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: peptidyl-lysine modification to peptidyl-hypusine (GO:0008612);; 	K00809|0|pps:100977998|DHPS; deoxyhypusine synthase; K00809 deoxyhypusine synthase [EC:2.5.1.46] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Deoxyhypusine synthase	Deoxyhypusine synthase GN=DHPS OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: deoxyhypusine synthase isoform X1 [Chrysochloris asiatica]
ENSG00000095066(HOOK2)	--	6.311708	336	4.749630278	288	6.714311253	321	6.515383269	369	7.28481478	421	6.562664375	377	0.963681785	0.103873984	normal	0.395905461	0.524036462	normal	0.938479713	0.222730568	normal	0.261788537	0.283441121	normal	--	--	--	K16611|0|pps:100981526|HOOK2; hook microtubule-tethering protein 2; K16611 protein HOOK2 (A)	--	--	--	HOOK protein	Protein Hook homolog 2 GN=HOOK2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: protein Hook homolog 2 isoform X2 [Ailuropoda melanoleuca]
ENSG00000095139(ARCN1)	--	42.38890402	2583	40.04147611	2365	44.305595	2575	46.30960816	2765	52.44692733	3105	44.46471527	2731	0.988340688	0.067360844	normal	0.859749635	0.371118851	normal	0.987957503	0.076521796	normal	0.36710422	0.172127812	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family;; Clathrin adaptor complex small chain	Coatomer subunit delta GN=ARCN1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit delta isoform X1 [Mustela putorius furo]
ENSG00000095203(EPB41L4B)	--	9.768921	564	9.16027	500	10.25252	570	12.120394	667	9.169791033	506	10.25516	586	0.946664514	0.210631245	normal	0.971105134	-0.004204627	normal	0.972921782	0.031564708	normal	0.770759472	0.084787966	normal	--	--	--	--	--	[R]	General function prediction only	FERM N-terminal domain;; FERM C-terminal PH-like domain;; FERM central domain;; FERM adjacent (FA)	Band 4.1-like protein 4B GN=EPB41L4B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: band 4.1-like protein 4B isoform 1 [Orcinus orca]
ENSG00000095209(TMEM38B)	--	12.42440122	514	9.620442544	420	10.3682706	423	14.42698114	611	13.4491451	565	18.24622316	814	0.942795312	0.217973598	normal	0.726019143	0.405173035	normal	2.48E-05	0.933631314	normal	0.065871081	0.531856861	normal	--	--	Molecular Function: cation channel activity (GO:0005261);; Biological Process: monovalent inorganic cation transport (GO:0015672);; Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	TRIC channel	Trimeric intracellular cation channel type B GN=TMEM38B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: trimeric intracellular cation channel type B [Odobenus rosmarus divergens]
ENSG00000095261(PSMD5)	--	26.35102822	1390	25.16162655	1314	25.66342707	1326	26.72967485	1405	28.58427701	1465	23.85112712	1246	0.983223423	-0.015330162	normal	0.976008754	0.13536124	normal	0.979005176	-0.097952883	normal	0.980487314	0.008952281	normal	--	--	Biological Process: proteasome assembly (GO:0043248);; 	"K06692|0|pps:100983980|PSMD5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 5; K06692 26S proteasome non-ATPase regulatory subunit 5 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome non-ATPase 26S subunit	26S proteasome non-ATPase regulatory subunit 5 GN=PSMD5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 5 isoform 1 [Dasypus novemcinctus]
ENSG00000095303(PTGS1)	--	0.046782262	4	0.034478725	3	0.079085146	6	0.023370909	2	0.203593595	14	0.031319281	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K00509|0|hsa:5742|PTGS1, COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1); K00509 prostaglandin-endoperoxide synthase 1 [EC:1.14.99.1] (A)"	Arachidonic acid metabolism (ko00590);; Platelet activation (ko04611);; Serotonergic synapse (ko04726)	[R]	General function prediction only	Animal haem peroxidase	Prostaglandin G/H synthase 1 (Precursor) GN=PTGS1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: prostaglandin G/H synthase 1 [Felis catus]
ENSG00000095319(NUP188)	--	18.7555	2125	17.6819	2009	20.465	2317	20.0823	2255	19.1447	2145	17.7992	2012	0.986937442	0.054793869	normal	0.985473838	0.073020326	normal	0.970153068	-0.21177072	normal	0.913344327	-0.030058315	normal	--	--	Cellular Component: nuclear pore (GO:0005643);; Molecular Function: structural constituent of nuclear pore (GO:0017056);; 	"K14311|0|hsa:23511|NUP188, KIAA0169, hNup188; nucleoporin 188kDa; K14311 nuclear pore complex protein Nup188 (A)"	RNA transport (ko03013)	[S]	Function unknown	Nucleoporin subcomplex protein binding to Pom34	Nucleoporin NUP188 homolog GN=NUP188 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: nucleoporin NUP188 homolog [Loxodonta africana]
ENSG00000095321(CRAT)	--	26.10565	1425	18.653516	987	22.492059	1214	19.728581	1005	24.0147	1279	18.842841	1013	0.203501753	-0.533909308	normal	0.842136434	0.351992776	normal	0.930058768	-0.269058243	normal	0.652838342	-0.158177191	normal	--	--	"Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K00624|0|hsa:1384|CRAT, CAT1; carnitine O-acetyltransferase (EC:2.3.1.7); K00624 carnitine O-acetyltransferase [EC:2.3.1.7] (A)"	Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Choline/Carnitine o-acyltransferase	Carnitine O-acetyltransferase GN=CRAT OS=Homo sapiens (Human) PE=1 SV=5	I	Lipid transport and metabolism	PREDICTED: carnitine O-acetyltransferase [Ceratotherium simum simum]
ENSG00000095370(SH2D3C)	--	0.142983084	8	0.114207938	3	0.170488754	8	0.068077702	4	0.020500614	0	0.05822307	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	--	--	SH2 domain;; RasGEF domain	SH2 domain-containing protein 3C GN=SH2D3C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH2 domain-containing protein 3C isoform 1 [Tursiops truncatus]
ENSG00000095380(NANS)	--	23.560553	469	24.095551	493	23.694171	484	31.73457002	636	33.285369	667	29.21981632	590	0.70540183	0.407456545	normal	0.695388296	0.413578146	normal	0.911156063	0.276632399	normal	0.060173328	0.36724281	normal	[M]	Cell wall/membrane/envelope biogenesis	Biological Process: carbohydrate biosynthetic process (GO:0016051);; 	K05304|0|ptr:743934|NANS; N-acetylneuraminic acid synthase; K05304 sialic acid synthase [EC:2.5.1.56 2.5.1.57] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	--	--	NeuB family;; SAF domain	Sialic acid synthase GN=NANS OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: sialic acid synthase [Capra hircus]
ENSG00000095383(TBC1D2)	--	6.858118356	460	6.2548465	436	8.323217894	574	15.12935724	1021	12.40703761	830	23.1672866	1552	3.39E-08	1.116877945	up	7.38E-05	0.905044	normal	1.84E-14	1.424338502	up	0.018863339	1.191506494	normal	[R]	General function prediction only	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain;; PH domain	TBC1 domain family member 2A GN=TBC1D2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 2A isoform X1 [Galeopterus variegatus]
ENSG00000095397(WHRN)	--	3.731758007	230	3.267254364	190	3.354485217	207	2.545575539	157	2.777084731	189	2.564492847	168	0.416336011	-0.577005235	normal	0.965569682	-0.028809829	normal	0.91180602	-0.306966936	normal	0.357777733	-0.307594046	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain	Whirlin GN=DFNB31 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: whirlin isoform X3 [Elephantulus edwardii]
ENSG00000095464(PDE6C)	--	0.0608034	4	0	0	0.0151745	0	0.0151755	1	0.0443326	2	0.0454697	3	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; "	"K13757|0|hsa:5146|PDE6C, ACHM5, COD4, PDEA2; phosphodiesterase 6C, cGMP-specific, cone, alpha prime (EC:3.1.4.35); K13757 cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [EC:3.1.4.35] (A)"	Purine metabolism (ko00230)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; GAF domain;; GAF domain;; GAF domain	"Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' (Precursor) GN=PDE6C OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' [Galeopterus variegatus]"
ENSG00000095485(CWF19L1)	--	10.87999265	509	11.06807835	522	12.07358248	561	12.695247	565	11.779826	540	11.368693	511	0.965518002	0.119410743	normal	0.971358799	0.027404983	normal	0.962229877	-0.142566081	normal	1	0.000246109	normal	--	--	--	--	--	[S]	Function unknown	Protein similar to CwfJ C-terminus 1;; Protein similar to CwfJ C-terminus 2	CWF19-like protein 1 GN=CWF19L1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: CWF19-like protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000095539(SEMA4G)	--	6.908070169	524	4.765274171	318	5.913637892	399	6.0914801	405	8.282448012	516	6.281344	380	0.731825926	-0.401135028	normal	0.040105256	0.674377154	normal	0.966774446	-0.078376336	normal	0.940617376	0.046908211	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06521|0|hsa:57715|SEMA4G; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G; K06521 semaphorin 4 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-4G (Precursor) GN=SEMA4G OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-4G [Bubalus bubalis]
ENSG00000095564(BTAF1)	--	10.95783263	1425	12.26953655	1604	11.148838	1422	12.61181194	1651	13.0734845	1689	11.3192368	1477	0.970679534	0.181364152	normal	0.983797213	0.053019913	normal	0.983042615	0.04640849	normal	0.686138746	0.092391564	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K15192|0|ptr:450604|BTAF1; BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa; K15192 TATA-binding protein-associated factor [EC:3.6.4.-] (A)"	--	[K]	Transcription	Domain of unknown function (DUF3535);; SNF2 family N-terminal domain;; HEAT repeat;; Helicase conserved C-terminal domain;; HEAT repeats;; Vacuolar 14 Fab1-binding region;; HEAT-like repeat	TATA-binding protein-associated factor 172 GN=BTAF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: TATA-binding protein-associated factor 172 [Canis lupus familiaris]
ENSG00000095574(IKZF5)	--	3.399327208	237	4.344884501	297	2.9491187	196	4.241315219	299	4.112641697	286	4.653124491	322	0.900319157	0.302676047	normal	0.964209121	-0.075482637	normal	0.055269943	0.703637778	normal	0.296765479	0.29163981	normal	[R]	General function prediction only	--	K09220|0|pon:100172776|IKZF5; IKAROS family zinc finger 5 (Pegasus); K09220 IKAROS family zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; C2H2-type zinc-finger domain;; Zinc finger, C2H2 type"	Zinc finger protein Pegasus GN=IKZF5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein Pegasus isoform X1 [Tupaia chinensis] 
ENSG00000095585(BLNK)	--	0.031167871	1	0	0	0	0	0	0	0.028368051	0	0.14304618	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K07371|0|ggo:101135942|BLNK; B-cell linker protein; K07371 B-cell linker protein (A)	NF-kappa B signaling pathway (ko04064);; Osteoclast differentiation (ko04380);; B cell receptor signaling pathway (ko04662);; Primary immunodeficiency (ko05340)	--	--	SH2 domain	B-cell linker protein GN=BLNK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: B-cell linker protein [Oryctolagus cuniculus]
ENSG00000095587(TLL2)	--	0.0773644	10	0.0995581	13	0.068264	8	0.0154524	2	0.0750706	9	0.0230513	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: proteolysis (GO:0006508);; 	K13047|0|hsa:7093|TLL2; tolloid-like 2; K13047 tolloid-like protein 2 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	CUB domain;; Astacin (Peptidase family M12A);; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain;; EGF-like domain;; Complement Clr-like EGF-like;; CUB-like domain	Tolloid-like protein 2 (Precursor) GN=TLL2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tolloid-like 2 isoform X1 [Sus scrofa]
ENSG00000095596(CYP26A1)	--	0.412346436	14	0.548366337	19	0.576638	20	1.456954	51	0.96834333	33	0.543593	19	0.008755566	1.728803706	up	0.937994825	0.730454487	normal	0.9888544	-0.07636691	normal	0.227046803	0.934810944	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07437|0|hsa:1592|CYP26A1, CP26, CYP26, P450RAI, P450RAI1; cytochrome P450, family 26, subfamily A, polypeptide 1 (EC:1.14.-.-); K07437 cytochrome P450, family 26, subfamily A (A)"	Retinol metabolism (ko00830)	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 26A1 GN=CYP26A1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 26A1-like isoform X1 [Elephantulus edwardii]
ENSG00000095637(SORBS1)	--	0.596787108	70	0.378151872	43	0.736521528	81	0.431537261	34	0.403683941	49	0.375661628	45	0.211101468	-1.039213112	normal	0.976173411	0.161688889	normal	0.456289341	-0.83507774	normal	0.228643067	-0.619433263	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06086|0|pps:100969228|SORBS1; sorbin and SH3 domain containing 1; K06086 sorbin and SH3 domain containing 1 (A)	PPAR signaling pathway (ko03320);; Adherens junction (ko04520);; Insulin signaling pathway (ko04910)	--	--	Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Sorbin homologous domain	Sorbin and SH3 domain-containing protein 1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: sorbin and SH3 domain-containing protein 1 isoform X13 [Sus scrofa]
ENSG00000095713(CRTAC1)	--	0.600513036	32	0.449188184	26	0.422983	24	1.043437658	59	1.207373	66	0.308568	15	0.723741564	0.822338906	normal	0.051380628	1.274476315	normal	0.972924173	-0.63531827	normal	0.481196689	0.74769124	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	"Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella;; FG-GAP repeat;; ASPIC and UnbV;; Calcium-binding EGF domain"	Cartilage acidic protein 1 (Precursor) GN=CRTAC1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: cartilage acidic protein 1 [Physeter catodon]
ENSG00000095739(BAMBI)	--	15.8683	480	11.6293	359	10.114	313	11.1743	343	16.744	508	9.7847	298	0.381323114	-0.513702682	normal	0.517893527	0.477718684	normal	0.965237549	-0.078751767	normal	0.978279137	-0.025491982	normal	--	--	Biological Process: negative regulation of transforming growth factor beta receptor signaling pathway (GO:0030512);; Biological Process: positive regulation of canonical Wnt signaling pathway (GO:0090263);; 	"K10162|7.24237e-179|hsa:25805|BAMBI, NMA; BMP and activin membrane-bound inhibitor; K10162 BMP and activin membrane-bound inhibitor (A)"	Wnt signaling pathway (ko04310);; TGF-beta signaling pathway (ko04350)	--	--	BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain;; Activin types I and II receptor domain	BMP and activin membrane-bound inhibitor homolog (Precursor) GN=BAMBI OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: BMP and activin membrane-bound inhibitor homolog isoform X1 [Galeopterus variegatus]
ENSG00000095752(IL11)	--	7.8939918	224	4.94260864	154	6.47163256	179	53.79657047	1619	59.56431408	1706	18.92937964	580	0	2.814326164	up	0	3.435482571	up	1.55E-15	1.679466697	up	0.002119735	2.786162754	up	--	--	--	K05417|1.85142e-72|ptr:736204|IL11; interleukin 11; K05417 interleukin 11 (A)	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Rheumatoid arthritis (ko05323)	--	--	Interleukin 11	Interleukin-11 (Precursor) GN=IL11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: interleukin-11 isoform X1 [Vicugna pacos]
ENSG00000095777(MYO3A)	--	0	0	0	0	0	0	0.00833926	1	0.040411201	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: myosin complex (GO:0016459);; 	"K08834|0|hsa:53904|MYO3A, DFNB30; myosin IIIA (EC:2.7.11.1); K08834 myosin III [EC:2.7.11.1] (A)"	--	[N]	Cell motility	Myosin head (motor domain);; Protein kinase domain;; Protein tyrosine kinase;; IQ calmodulin-binding motif	Myosin-IIIa GN=MYO3A OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: myosin-IIIa [Ceratotherium simum simum]
ENSG00000095787(WAC)	--	41.61470381	2451	42.83392573	2489	41.55601447	2435	40.01268345	2422	43.98906175	2583	41.70056959	2430	0.988074645	-0.04797363	normal	0.988392905	0.032035748	normal	0.988564657	-0.011249906	normal	0.978728302	-0.009482208	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[A]	RNA processing and modification	WW domain	WW domain-containing adapter protein with coiled-coil GN=WAC OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: WW domain-containing adapter protein with coiled-coil-like isoform X1 [Leptonychotes weddellii]
ENSG00000095794(CREM)	--	23.57117063	455	20.40239728	423	19.25870495	395	28.48484222	584	24.6684949	533	24.16304651	511	0.86059307	0.328288981	normal	0.882003449	0.311058716	normal	0.814761006	0.361957621	normal	0.115419089	0.333089588	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09052|0|mcf:101926485|uncharacterized LOC101926485; K09052 cAMP response element modulator (A)	Adrenergic signaling in cardiomyocytes (ko04261);; HTLV-I infection (ko05166)	[K]	Transcription	bZIP transcription factor;; pKID domain;; Basic region leucine zipper	cAMP-responsive element modulator GN=CREM OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: cAMP-responsive element modulator isoform X2 [Ursus maritimus]
ENSG00000095906(NUBP2)	--	38.6581218	889	41.15566254	966	39.96151622	922	46.94082	1080	43.348671	997	46.99603363	1080	0.938154236	0.249551945	normal	0.978648168	0.02410661	normal	0.952041946	0.219568138	normal	0.430205206	0.163775167	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"ParA/MinD ATPase like;; CobQ/CobB/MinD/ParA nucleotide binding domain;; ATPase MipZ;; AAA domain;; Anion-transporting ATPase;; ArgK protein;; 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family"	Cytosolic Fe-S cluster assembly factor NUBP2 {ECO:0000255|HAMAP-Rule:MF_03039} OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cytosolic Fe-S cluster assembly factor NUBP2 isoform X1 [Equus przewalskii]
ENSG00000095932(SMIM24)	--	0.08882629	1	0	0	0	0	0.0393747	1	0.0388837	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Small integral membrane protein 24 (Precursor) GN=SMIM24 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: small integral membrane protein 24 [Camelus dromedarius]
ENSG00000095951(HIVEP1)	--	4.348191644	560	2.982911666	551	5.404065142	550	5.453295875	735	3.591483074	692	6.121066585	881	0.809138247	0.360619308	normal	0.887460083	0.30654102	normal	0.018474209	0.669950366	normal	0.009684792	0.453896946	normal	--	--	--	"K09239|0|hsa:3096|HIVEP1, CIRIP, CRYBP1, GAAP, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A; human immunodeficiency virus type I enhancer binding protein 1; K09239 human immunodeficiency virus type I enhancer-binding protein (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 40 GN=HIVEP1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 40 [Ceratotherium simum simum]
ENSG00000095970(TREM2)	--	0	0	0	0	0	0	0	0	0	0	0.117938515	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K14378|2.61465e-141|ggo:101124342|TREM2; triggering receptor expressed on myeloid cells 2 isoform 1; K14378 triggering receptor expressed on myeloid cells 2 (A)	Osteoclast differentiation (ko04380)	--	--	Immunoglobulin V-set domain	Triggering receptor expressed on myeloid cells 2 (Precursor) GN=TREM2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: triggering receptor expressed on myeloid cells 2 [Galeopterus variegatus]
ENSG00000096006(CRISP3)	--	0.27916109	9	0.031246946	1	0.291931349	6	0	0	0.149506739	4	0.166878497	2	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	--	--	[S]	Function unknown	Crisp;; Cysteine-rich secretory protein family	Cysteine-rich secretory protein 3 (Precursor) GN=CRISP3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"Cysteine-rich secretory protein 2, partial [Bos mutus]"
ENSG00000096060(FKBP5)	--	8.442261363	627	7.83088344	580	7.86949942	576	6.609476197	492	8.340021954	613	4.637534154	342	0.772563297	-0.379586343	normal	0.97148613	0.058259849	normal	0.005118201	-0.75775227	normal	0.317495366	-0.323240739	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K09571|0|hsa:2289|FKBP5, AIG6, FKBP51, FKBP54, P54, PPIase, Ptg-10; FK506 binding protein 5 (EC:5.2.1.8); K09571 FK506-binding protein 4/5 [EC:5.2.1.8] (A)"	Estrogen signaling pathway (ko04915)	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Peptidyl-prolyl cis-trans isomerase FKBP5 GN=FKBP5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP5 isoform 1 [Orcinus orca] 
ENSG00000096063(SRPK1)	--	16.962251	1366	16.11159454	1291	18.5462149	1453	25.2075245	2020	21.804732	1752	18.50174357	1475	0.210324613	0.533069693	normal	0.694841235	0.41866476	normal	0.983770855	0.013374993	normal	0.089221846	0.330392805	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K15409|0|hsa:6732|SRPK1, SFRSK1; SRSF protein kinase 1 (EC:2.7.11.1); K15409 serine/threonine-protein kinase SRPK1 [EC:2.7.11.1] (A)"	Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	SRSF protein kinase 1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SRSF protein kinase 1 isoform X1 [Galeopterus variegatus]
ENSG00000096070(BRPF3)	--	4.185754923	524	4.824192091	578	3.95121269	503	4.436467146	558	5.454860357	638	5.173889058	656	0.970942731	0.059696418	normal	0.966230432	0.12075956	normal	0.785198725	0.373858968	normal	0.429928644	0.185654455	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11350|0|hsa:27154|BRPF3; bromodomain and PHD finger containing, 3; K11350 bromodomain and PHD finger-containing protein 3 (A)"	--	[R]	General function prediction only	PHD-zinc-finger like domain;; Enhancer of polycomb-like;; PHD-like zinc-binding domain;; Bromodomain;; PWWP domain;; PHD-finger	Bromodomain and PHD finger-containing protein 3 GN=BRPF3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: bromodomain and PHD finger-containing protein 3 isoform X1 [Vicugna pacos]
ENSG00000096080(MRPS18A)	--	22.41982317	392	19.874493	346	19.804312	348	22.24549	380	24.33713	409	22.388028	391	0.966813581	-0.075386369	normal	0.939010596	0.219020943	normal	0.955999799	0.15913711	normal	0.764275791	0.098616225	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02963|1.79404e-70|hsa:55168|MRPS18A, HumanS18b, MRP-S18-3, MRPS18-3, S18bmt; mitochondrial ribosomal protein S18A; K02963 small subunit ribosomal protein S18 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S18	"28S ribosomal protein S18a, mitochondrial (Precursor) GN=MRPS18A OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"28S ribosomal protein S18a, mitochondrial [Bos mutus]"
ENSG00000096092(TMEM14A)	--	33.3729	367	36.4725	405	38.5064	422	40.904	455	35.5826	390	39.1842	433	0.909467449	0.278206599	normal	0.966233847	-0.075586696	normal	0.969998095	0.028730938	normal	0.820476404	0.07682137	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Transmembrane proteins 14C	Transmembrane protein 14A GN=TMEM14A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 14A [Ochotona princeps]
ENSG00000096093(EFHC1)	--	8.877998757	476	6.620173826	348	9.574245186	508	7.015955084	393	6.82377288	360	7.462884339	387	0.886317479	-0.306174876	normal	0.967592627	0.027366119	normal	0.740043288	-0.399419711	normal	0.361716581	-0.245384847	normal	--	--	--	--	--	[S]	Function unknown	Repeat of unknown function (DUF1126)	EF-hand domain-containing protein 1 GN=EFHC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: EF-hand domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000096384(HSP90AB1)	--	523.923564	30011	518.0198372	29735	579.737544	32995	583.668338	33471	512.7398566	29021	386.5421186	22001	0.998022511	0.126581861	normal	0.998302584	-0.056488493	normal	0.252861751	-0.592936245	normal	0.58351055	-0.15659959	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: protein folding (GO:0006457);; Biological Process: response to stress (GO:0006950);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K04079|0|pale:102887985|HSP90AB1; heat shock protein 90kDa alpha (cytosolic), class B member 1; K04079 molecular chaperone HtpG (A)"	Protein processing in endoplasmic reticulum (ko04141);; PI3K-Akt signaling pathway (ko04151);; Antigen processing and presentation (ko04612);; NOD-like receptor signaling pathway (ko04621);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Pathways in cancer (ko05200);; Prostate cancer (ko05215)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Hsp90 protein;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	Heat shock protein HSP 90-beta GN=HSP90AB1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein HSP 90-beta [Pteropus alecto]
ENSG00000096401(CDC5L)	--	10.92188269	996	12.97525191	1162	13.56697017	1145	12.0420915	1124	12.9711328	1122	12.323817	1123	0.971293765	0.143383835	normal	0.978770885	-0.071868757	normal	0.980587447	-0.03623279	normal	0.985612711	0.00743114	normal	[KAD]	"Transcription;; RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	--	"K12860|0|hsa:988|CDC5L, CDC5, CDC5-LIKE, CEF1, PCDC5RP, dJ319D22.1; cell division cycle 5-like; K12860 pre-mRNA-splicing factor CDC5/CEF1 (A)"	Spliceosome (ko03040)	[AD]	"RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	pre-mRNA splicing factor component;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain	Cell division cycle 5-like protein GN=CDC5L OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cell division cycle 5-like protein [Galeopterus variegatus]
ENSG00000096433(ITPR3)	--	19.0719	4070	15.21359	3283	17.86429	3870	27.74621	5858	26.24437	5566	25.99586	5554	0.482334532	0.494390812	normal	0.00242786	0.739934959	normal	0.381141238	0.512734037	normal	8.25E-05	0.575983851	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: calcium channel activity (GO:0005262);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04960|0|hsa:3710|ITPR3, IP3R, IP3R3; inositol 1,4,5-trisphosphate receptor, type 3; K04960 inositol 1,4,5-triphosphate receptor type 3 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	"RIH domain;; Inositol 1,4,5-trisphosphate/ryanodine receptor;; MIR domain;; RyR and IP3R Homology associated;; Ion transport protein"	"Inositol 1,4,5-trisphosphate receptor type 3 GN=ITPR3 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: inositol 1,4,5-trisphosphate receptor type 3 [Vicugna pacos]"
ENSG00000096654(ZNF184)	--	1.5582768	97	2.132295145	132	1.731532945	110	1.434917712	90	1.157533416	74	1.519748916	97	0.967578796	-0.136644256	normal	0.120087163	-0.843279845	normal	0.961349174	-0.186998676	normal	0.35879938	-0.398422018	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7738|ZNF184; zinc finger protein 184; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 184 GN=ZNF184 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: zinc finger protein 184-like [Tursiops truncatus]
ENSG00000096696(DSP)	--	20.14945	4461	21.59111	4896	19.14582	4254	18.45615	4003	17.48643	3853	20.01979	4360	0.98463576	-0.187049742	normal	0.897602821	-0.366919831	normal	0.992475308	0.027207106	normal	0.360753112	-0.177145507	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; 	K10381|0|pps:100975288|DSP; desmoplakin; K10381 desmoplakin (A)	Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[Z]	Cytoskeleton	Plectin repeat	Desmoplakin GN=DSP OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: desmoplakin isoform X1 [Felis catus]
ENSG00000096717(SIRT1)	--	11.94052123	821	12.34137571	854	11.48828707	769	9.11077506	633	9.875583522	674	11.0593158	755	0.701551556	-0.405142697	normal	0.81234204	-0.362190199	normal	0.975976523	-0.034729466	normal	0.1684059	-0.266015721	normal	[K]	Transcription	Molecular Function: NAD+ binding (GO:0070403);; 	K11411|0|nle:100605499|SIRT1; sirtuin 1; K11411 NAD-dependent deacetylase sirtuin 1 [EC:3.5.1.-] (A)	FoxO signaling pathway (ko04068);; AMPK signaling pathway (ko04152);; Amphetamine addiction (ko05031);; MicroRNAs in cancer (ko05206)	[BK]	Chromatin structure and dynamics;; Transcription	Sir2 family	SirtT1 75 kDa fragment GN=SIRT1 OS=Homo sapiens (Human) PE=1 SV=2	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: NAD-dependent protein deacetylase sirtuin-1 isoform 1 [Trichechus manatus latirostris]
ENSG00000096746(HNRNPH3)	--	90.58599	3161	90.98509	3248	96.68115	3384	105.2740461	3602	76.590128	2621	96.221968	3369	0.985224319	0.157513128	normal	0.917802228	-0.330689065	normal	0.991020907	-0.014694001	normal	0.856106482	-0.051368257	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K12898|6.1072e-64|ngi:103733762|Hnrnph3; heterogeneous nuclear ribonucleoprotein H3 (2H9); K12898 heterogeneous nuclear ribonucleoprotein F/H (A)	--	[A]	RNA processing and modification	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoprotein H3 GN=HNRNPH3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein H3 [Ochotona princeps]
ENSG00000096872(IFT74)	--	9.470839727	422	9.773153893	408	9.804365072	460	7.588975	365	9.509297422	431	9.226346272	426	0.931442064	-0.239241166	normal	0.967832972	0.057484842	normal	0.963826167	-0.118666365	normal	0.751815923	-0.09861635	normal	--	--	--	--	--	--	--	--	Intraflagellar transport protein 74 homolog GN=IFT74 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: intraflagellar transport protein 74 homolog isoform X1 [Sus scrofa] 
ENSG00000096968(JAK2)	--	2.255193491	230	2.882120033	278	2.451671782	224	2.614848089	269	2.3697117	237	3.988212813	392	0.948207946	0.193941214	normal	0.92877247	-0.250148781	normal	0.006398139	0.79495493	normal	0.556061431	0.274525603	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04447|0|hsa:3717|JAK2, JTK10, THCYT3; Janus kinase 2 (EC:2.7.10.2); K04447 Janus kinase 2 [EC:2.7.10.2] (A)"	Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; Cholinergic synapse (ko04725);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain	Tyrosine-protein kinase JAK2 GN=JAK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase JAK2 [Condylura cristata]
ENSG00000096996(IL12RB1)	--	0.0178175	1	0	0	0.0274415	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05063|0|hsa:3594|IL12RB1, CD212, IL-12R-BETA1, IL12RB, IMD30; interleukin 12 receptor, beta 1; K05063 interleukin 12 receptor beta-1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Inflammatory bowel disease (IBD) (ko05321)	--	--	Fibronectin type III domain	Interleukin-12 receptor subunit beta-1 (Precursor) GN=IL12RB1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: interleukin-12 receptor subunit beta-1 [Galeopterus variegatus]
ENSG00000097007(ABL1)	--	26.000595	3259	27.2288072	3146	25.3631184	3130	29.14101078	3564	27.24885817	3576	27.66320601	3629	0.989216901	0.098191447	normal	0.984377252	0.16332783	normal	0.979059091	0.205025883	normal	0.436997296	0.154414001	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: non-membrane spanning protein tyrosine kinase activity (GO:0004715);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K06619|0|ptr:464802|ABL1; ABL proto-oncogene 1, non-receptor tyrosine kinase; K06619 abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Cell cycle (ko04110);; Axon guidance (ko04360);; Neurotrophin signaling pathway (ko04722);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Chronic myeloid leukemia (ko05220);; Viral myocarditis (ko05416)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; F-actin binding;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Bacterial SH3 domain	Tyrosine-protein kinase ABL1 GN=ABL1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase ABL1 isoform 1 [Ceratotherium simum simum]
ENSG00000097021(ACOT7)	--	41.6935927	1257	37.18047303	1153	43.24620652	1350	36.13656701	1088	35.78859476	1072	29.77315877	888	0.947510647	-0.238824238	normal	0.973909296	-0.126342256	normal	0.048321271	-0.611767943	normal	0.051586989	-0.324390294	normal	[I]	Lipid transport and metabolism	--	K17360|0|nle:100581694|ACOT7; acyl-CoA thioesterase 7; K17360 acyl-coenzyme A thioesterase 7 [EC:3.1.2.2] (A)	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040)	[I]	Lipid transport and metabolism	Thioesterase superfamily	Cytosolic acyl coenzyme A thioester hydrolase GN=ACOT7 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: cytosolic acyl coenzyme A thioester hydrolase isoform X3 [Tupaia chinensis]
ENSG00000097033(SH3GLB1)	--	12.56996171	1204	12.21703659	1186	10.79719517	1060	12.07536981	1217	14.68302205	1445	12.3114476	1229	0.98164651	-0.015319044	normal	0.938810636	0.263234422	normal	0.959574415	0.204857552	normal	0.459582476	0.152266719	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	"K11248|0|hsa:51100|SH3GLB1, Bif-1, PPP1R70, dJ612B15.2; SH3-domain GRB2-like endophilin B1; K11248 endophilin-B (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	BAR domain;; Variant SH3 domain;; Bin/amphiphysin/Rvs domain for vesicular trafficking;; SH3 domain;; Variant SH3 domain	Endophilin-B1 GN=SH3GLB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endophilin-B1 isoform X1 [Oryctolagus cuniculus]
ENSG00000097046(CDC7)	--	6.749168	343	8.278599597	415	7.2859324	358	5.0011422	255	5.264973	255	4.500012011	226	0.644614434	-0.456163941	normal	0.0249546	-0.720655617	normal	0.07541873	-0.66834306	normal	0.004439088	-0.622217373	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K02214|0|hsa:8317|CDC7, CDC7L1, HsCDC7, Hsk1, huCDC7; cell division cycle 7 (EC:2.7.11.1); K02214 cell division control protein 7 [EC:2.7.11.1] (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	Protein kinase domain;; Protein tyrosine kinase	Cell division cycle 7-related protein kinase GN=CDC7 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cell division cycle 7-related protein kinase isoform 2 [Ceratotherium simum simum]
ENSG00000097096(SYDE2)	--	1.310460424	117	1.813773683	149	1.696159931	140	1.066460914	91	1.359769633	113	1.51910794	128	0.908497068	-0.38761349	normal	0.861530702	-0.415556289	normal	0.962753059	-0.136037076	normal	0.461094974	-0.310401172	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	RhoGAP domain	Rho GTPase-activating protein SYDE2 GN=SYDE2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein SYDE2 [Galeopterus variegatus]
ENSG00000099139(PCSK5)	--	0.644399198	71	0.563696194	64	0.413010357	41	0.304080655	33	0.580847949	65	0.488512626	55	0.129621743	-1.100405729	normal	0.974495911	0.000919692	normal	0.956851273	0.402651666	normal	0.74863308	-0.222489262	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K08654|0|hsa:5125|PCSK5, PC5, PC6, PC6A, SPC6; proprotein convertase subtilisin/kexin type 5 (EC:3.4.21.-); K08654 proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family;; Growth factor receptor domain IV;; Proprotein convertase P-domain;; Giardia variant-specific surface protein;; Furin-like cysteine rich region	Proprotein convertase subtilisin/kexin type 5 (Precursor) GN=PCSK5 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proprotein convertase subtilisin/kexin type 5 isoform X1 [Physeter catodon]
ENSG00000099194(SCD)	--	560.825	50531	770.419	69478	597.584	53457	236.053	21306	241.256	21610	714.912	64519	1.16E-12	-1.276679479	down	0	-1.706213172	down	0.996279623	0.263046977	normal	0.336139236	-0.709257824	normal	[I]	Lipid transport and metabolism	--	"K00507|0|hsa:6319|SCD, FADS5, MSTP008, SCD1, SCDOS; stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1); K00507 stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] (A)"	Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; AMPK signaling pathway (ko04152)	[I]	Lipid transport and metabolism	Fatty acid desaturase	Acyl-CoA desaturase GN=SCD OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: acyl-CoA desaturase [Galeopterus variegatus]
ENSG00000099203(TMED1)	--	16.473041	381	18.51628	411	16.261505	395	13.502375	318	14.76267	333	15.832687	367	0.902500825	-0.29031291	normal	0.872516724	-0.323716736	normal	0.963197676	-0.113911467	normal	0.351219896	-0.242360156	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 1 (Precursor) GN=TMED1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 1 [Leptonychotes weddellii]
ENSG00000099204(ABLIM1)	--	14.85095733	1796	15.25900014	1847	16.24926075	1895	20.15652593	2431	19.78314942	2392	24.53141168	2994	0.747498026	0.405631041	normal	0.875349026	0.351353554	normal	0.017936743	0.651167989	normal	0.002686215	0.476729731	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	K07520|0|mcf:101925236|uncharacterized LOC101925236; K07520 actin-binding LIM protein (A)	Axon guidance (ko04360)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain;; Villin headpiece domain	Actin-binding LIM protein 1 GN=ABLIM1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: actin-binding LIM protein 1 isoform X1 [Camelus ferus]
ENSG00000099219(ERMP1)	--	35.52534	2924	32.9225	2734	30.99472	2539	40.66168	3366	38.72675	3161	43.16978	3549	0.982824819	0.172175233	normal	0.979715654	0.187844537	normal	0.511453231	0.474620549	normal	0.098192599	0.27651776	normal	[R]	General function prediction only	--	--	--	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Peptidase family M28;; Peptidase family M20/M25/M40	"Endoplasmic reticulum metallopeptidase 1 {ECO:0000250|UniProtKB:Q6UPR8, ECO:0000312|HGNC:HGNC:23703} OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: endoplasmic reticulum metallopeptidase 1, partial [Tupaia chinensis]"
ENSG00000099246(RAB18)	--	22.16636325	1399	22.37130247	1297	23.7905606	1470	23.3677512	1496	22.76052497	1453	21.11708556	1352	0.982267182	0.06581205	normal	0.975003563	0.142272876	normal	0.977357037	-0.128874154	normal	0.93492335	0.024700509	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07910|5.61176e-134|hsa:22931|RAB18, RAB18LI1, WARBM3; RAB18, member RAS oncogene family; K07910 Ras-related protein Rab-18 (A)"	--	[R]	General function prediction only	Ras family;; ADP-ribosylation factor family;; Miro-like protein	Ras-related protein Rab-18 (Precursor) GN=RAB18 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	"hypothetical protein M91_00324, partial [Bos mutus]"
ENSG00000099250(NRP1)	--	111.5829955	10787	116.9108999	11742	108.015598	10652	72.145979	7478	60.7613248	6007	73.6340908	7057	0.249386343	-0.559305299	normal	6.36E-07	-0.988206713	normal	0.103126466	-0.602183061	normal	2.56E-06	-0.713362019	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K06724|0|ptr:450397|NRP1; neuropilin 1; K06724 neuropilin 1 (A)	Axon guidance (ko04360);; HTLV-I infection (ko05166)	--	--	CUB domain;; F5/8 type C domain;; MAM domain;; Domain of unknown function (DUF3481)	Neuropilin-1 (Precursor) GN=NRP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neuropilin-1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000099256(PRTFDC1)	--	7.011691118	180	9.351417	185	7.77371656	155	16.43699	416	17.89432833	446	15.06347481	308	7.04E-07	1.170997704	up	8.58E-08	1.241353116	up	0.000403327	0.975489627	normal	3.88E-06	1.14771134	up	[F]	Nucleotide transport and metabolism	Biological Process: nucleoside metabolic process (GO:0009116);; 	--	--	[F]	Nucleotide transport and metabolism	Phosphoribosyl transferase domain	Phosphoribosyltransferase domain-containing protein 1 GN=PRTFDC1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: phosphoribosyltransferase domain-containing protein 1 [Pteropus alecto]
ENSG00000099260(PALMD)	--	0.324114259	19	0.249241593	13	0.266284203	11	2.281749263	134	2.500748997	141	2.088384318	122	6.27E-14	2.692916678	up	0	3.275543168	up	2.22E-16	3.29549746	up	1.78E-16	3.184781349	up	--	--	Biological Process: regulation of cell shape (GO:0008360);; Cellular Component: membrane (GO:0016020);; 	"K16519|0|hsa:54873|PALMD, C1orf11, PALML; palmdelphin; K16519 A-kinase anchor protein 2 (A)"	--	--	--	Paralemmin	Palmdelphin GN=PALMD OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: palmdelphin [Ceratotherium simum simum]
ENSG00000099282(TSPAN15)	--	53.84052022	1496	53.25491823	1523	45.383948	1288	71.3504089	2009	74.28067559	2050	53.96009708	1511	0.765652875	0.394184699	normal	0.743378568	0.406931983	normal	0.958300994	0.221838907	normal	0.115419089	0.348787393	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17297|0|ptr:450507|TSPAN15; tetraspanin 15; K17297 tetraspanin-15 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-15 GN=TSPAN15 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetraspanin-15 isoform X2 [Mustela putorius furo]
ENSG00000099284(H2AFY2)	--	16.670962	679	17.22067549	709	15.4374	639	19.300312	791	22.882	933	19.1216	786	0.956092963	0.189037271	normal	0.790163023	0.373967614	normal	0.903958891	0.289802494	normal	0.129902171	0.287069415	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; Biological Process: protein metabolic process (GO:0019538);; 	K11251|0|tup:102491433|core histone macro-H2A.2-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[BK]	Chromatin structure and dynamics;; Transcription	Macro domain;; Core histone H2A/H2B/H3/H4	Core histone macro-H2A.2 GN=H2AFY2 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: core histone macro-H2A.2 [Orycteropus afer afer]
ENSG00000099290(WASHC2A)	--	7.249242145	582	7.861246672	688	6.667288283	647	7.837013611	627	7.217867323	642	12.15441383	1006	0.971114074	0.076419641	normal	0.96736791	-0.12098645	normal	0.04088101	0.627316066	normal	0.637294429	0.227242306	normal	--	--	--	"K18462|0|hsa:387680|FAM21A, FAM21B, bA56A21.1, bA98I6.1; family with sequence similarity 21, member A; K18462 WASH complex subunit FAM21 (A)"	--	--	--	"WASH complex subunit CAP-Z interacting, central region"	WASH complex subunit FAM21A GN=FAM21A OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: WASH complex subunit FAM21A-like [Equus caballus]
ENSG00000099308(MAST3)	--	2.659209286	320	2.387009396	293	2.985166657	367	1.908085115	231	1.757550002	215	1.622852736	197	0.537730752	-0.49818211	normal	0.661037655	-0.465175639	normal	0.000874105	-0.900727258	normal	0.005989577	-0.629281208	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08789|0|hsa:23031|MAST3; microtubule associated serine/threonine kinase 3 (EC:2.7.11.1); K08789 microtubule-associated serine/threonine kinase [EC:2.7.11.1] (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	Domain of unknown function (DUF1908);; Protein kinase domain;; Protein tyrosine kinase;; PDZ domain (Also known as DHR or GLGF)	Microtubule-associated serine/threonine-protein kinase 3 GN=MAST3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	Microtubule-associated serine/threonine-protein kinase 3 [Bos mutus]
ENSG00000099326(MZF1)	--	8.574363162	425	9.064558816	436	8.3814985	414	7.81738245	366	9.506095886	456	11.7760327	547	0.9285065	-0.245493972	normal	0.969068458	0.043132839	normal	0.752016848	0.392367874	normal	0.825301222	0.082576611	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09221|0|ptr:456356|MZF1, ZNF42; myeloid zinc finger 1; K09221 myeloid zinc finger protein 1 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; SCAN domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc-finger domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; Protein of unknown function (FYDLN_acid)"	Myeloid zinc finger 1 GN=MZF1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: myeloid zinc finger 1 [Galeopterus variegatus] 
ENSG00000099330(OCEL1)	--	10.05359486	162	6.095296913	107	8.778296129	146	6.420205556	113	9.393818817	153	9.372556582	157	0.656143861	-0.544285963	normal	0.77805208	0.488690749	normal	0.964825699	0.095550157	normal	0.999661041	0.007610676	normal	--	--	--	--	--	[K]	Transcription	Occludin homology domain	Occludin/ELL domain-containing protein 1 GN=OCEL1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: occludin/ELL domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000099331(MYO9B)	--	12.78791562	1945	11.72749115	1801	12.41433301	2080	10.82169617	1711	12.0755427	1881	10.06449018	1441	0.96579581	-0.215580927	normal	0.98527464	0.041241224	normal	0.197074537	-0.537332551	normal	0.183621959	-0.232466662	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: signal transduction (GO:0007165);; Cellular Component: myosin complex (GO:0016459);; 	K10360|0|ptr:455820|MYO9B; myosin IXB; K10360 myosin IX (A)	--	[N]	Cell motility	Myosin head (motor domain);; RhoGAP domain;; Ras association (RalGDS/AF-6) domain;; IQ calmodulin-binding motif	Unconventional myosin-IXb GN=MYO9B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: unconventional myosin-IXb isoform X4 [Galeopterus variegatus]
ENSG00000099337(KCNK6)	--	1.572826	198	1.68940576	219	1.909625043	245	2.9902037	379	2.85754048	358	1.8127678	229	0.000822998	0.900730921	normal	0.065896358	0.683874004	normal	0.962455711	-0.105054715	normal	0.138450342	0.522942932	normal	[P]	Inorganic ion transport and metabolism	--	"K04917|0|hsa:9424|KCNK6, K2p6.1, KCNK8, TOSS, TWIK-2, TWIK2; potassium channel, subfamily K, member 6; K04917 potassium channel subfamily K member 6 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 6 GN=KCNK6 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 6 [Sus scrofa]
ENSG00000099338(CATSPERG)	--	0.106407055	7	0.150367375	10	0.152551736	9	0.05447402	3	0.176803317	10	0.201678778	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: CatSper complex (GO:0036128);; Cellular Component: sperm principal piece (GO:0097228);; 	"K16894|0|hsa:57828|CATSPERG, C19orf15; catsper channel auxiliary subunit gamma; K16894 cation channel sperm-associated protein subunit gamma (A)"	--	--	--	Cation channel sperm-associated protein subunit gamma	Cation channel sperm-associated protein subunit gamma (Precursor) GN=CATSPERG OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: cation channel sperm-associated protein subunit gamma [Ceratotherium simum simum]
ENSG00000099341(PSMD8)	--	231.0023153	4248	207.2262722	3737	231.4699665	4275	230.2256986	4476	232.8167565	4418	211.746062	3959	0.992378361	0.044578299	normal	0.97918467	0.220004337	normal	0.98972947	-0.119036025	normal	0.862403947	0.046766084	normal	--	--	--	"K03031|0|nle:100592683|PSMD8; proteasome (prosome, macropain) 26S subunit, non-ATPase, 8; K03031 26S proteasome regulatory subunit N12 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	"COP9 signalosome, subunit CSN8;; SAC3/GANP/Nin1/mts3/eIF-3 p25 family"	26S proteasome non-ATPase regulatory subunit 8 GN=PSMD8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 8 [Lipotes vexillifer]
ENSG00000099364(FBXL19)	--	39.74130464	1787	41.09007984	1927	40.10558197	1724	46.15519711	2071	41.267694	1929	49.02633574	2089	0.974383883	0.181810359	normal	0.98608331	-0.019914366	normal	0.945929712	0.268546966	normal	0.485777474	0.141787152	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	"K10285|0|hsa:54620|FBXL19, CXXC11, Fbl19, JHDM1C; F-box and leucine-rich repeat protein 19; K10285 F-box and leucine-rich repeat protein 19 (A)"	--	[R]	General function prediction only	CXXC zinc finger domain;; F-box domain;; Leucine Rich Repeat;; Leucine rich repeat;; F-box-like	F-box/LRR-repeat protein 19 GN=FBXL19 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: F-box/LRR-repeat protein 19 isoform X1 [Galeopterus variegatus]
ENSG00000099365(STX1B)	--	1.826468	187	1.550106789	127	1.608619	165	1.0235067	89	0.994015	94	1.176536	119	0.000686766	-1.088717615	down	0.855617071	-0.449278915	normal	0.779335606	-0.474650154	normal	0.034911146	-0.685632236	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: membrane (GO:0016020);; 	K08486|0|tup:102492260|STX1B; syntaxin 1B; K08486 syntaxin 1B/2/3 (A)	SNARE interactions in vesicular transport (ko04130);; Synaptic vesicle cycle (ko04721)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Syntaxin;; SNARE domain	Syntaxin-1B GN=STX1B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-1B [Myotis brandtii] 
ENSG00000099377(HSD3B7)	--	8.076629611	319	7.669085039	253	7.739598186	316	13.32899786	523	11.86204615	443	12.94087508	509	0.031474421	0.679841341	normal	0.006781412	0.78316153	normal	0.034487802	0.676873844	normal	0.000234988	0.710966091	normal	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K12408|0|ptr:454059|HSD3B7; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; K12408 cholest-5-ene-3beta,7alpha-diol 3beta-dehydrogenase [EC:1.1.1.181] (A)"	Primary bile acid biosynthesis (ko00120)	[IE]	Lipid transport and metabolism;; Amino acid transport and metabolism	3-beta hydroxysteroid dehydrogenase/isomerase family;; NAD dependent epimerase/dehydratase family;; Male sterility protein;; short chain dehydrogenase;; NADH(P)-binding;; KR domain;; Polysaccharide biosynthesis protein;; RmlD substrate binding domain;; NmrA-like family	3 beta-hydroxysteroid dehydrogenase type 7 GN=HSD3B7 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 3 beta-hydroxysteroid dehydrogenase type 7 [Ceratotherium simum simum]
ENSG00000099381(SETD1A)	--	9.50785686	1308	9.24073	1267	8.701039	1231	7.93924	1082	8.381304	1161	9.094778	1270	0.903459024	-0.30410084	normal	0.972472209	-0.147291378	normal	0.981682776	0.03666195	normal	0.519359539	-0.136345372	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	K11422|0|ptr:468101|SETD1A; SET domain containing 1A; K11422 histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43] (A)	Lysine degradation (ko00310)	--	--	"COMPASS (Complex proteins associated with Set1p) component N;; SET domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: histone-lysine N-methyltransferase SETD1A [Galeopterus variegatus] 
ENSG00000099385(BCL7C)	--	18.113359	525	18.97262	567	16.249192	497	17.970188	530	17.28959	509	17.619091	512	0.972151244	-0.017107499	normal	0.954635319	-0.176612169	normal	0.971406699	0.034503076	normal	0.86544668	-0.056405136	normal	--	--	--	--	--	[R]	General function prediction only	"BCL7, N-terminal conserver region"	B-cell CLL/lymphoma 7 protein family member C GN=BCL7C OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: B-cell CLL/lymphoma 7 protein family member C isoform 1 [Canis lupus familiaris]
ENSG00000099399(MAGEB2)	--	0	0	0	0	0	0	0.0364478	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen B2 GN=MAGEB2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: melanoma-associated antigen B4-like isoform X1 [Sus scrofa] 
ENSG00000099617(EFNA2)	--	0.936475	10	1.32124928	15	2.093087	23	2.235528	25	1.489718	16	1.646324	18	0.872673494	1.173888529	normal	--	--	--	0.985027606	-0.336836561	normal	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	K05462|1.77301e-136|bta:614453|EFNA2; ephrin-A2; K05462 ephrin-A (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Ephrin	Ephrin-A2 (Precursor) GN=EFNA2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	ephrin-A2 precursor [Bos taurus] 
ENSG00000099622(CIRBP)	--	44.83302964	776	37.2628611	706	36.60731105	727	67.6091934	1260	74.25073525	1349	59.66543891	1097	0.014501162	0.667416631	normal	2.31E-05	0.911287992	normal	0.091346724	0.584248667	normal	8.08E-07	0.724936303	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13195|7.09414e-85|pps:100977816|CIRBP; cold inducible RNA binding protein; K13195 cold-inducible RNA-binding protein (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Cold-inducible RNA-binding protein GN=CIRBP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cold-inducible RNA-binding protein [Orycteropus afer afer]
ENSG00000099624(ATP5D)	--	89.0907053	828	88.94860586	833	92.733507	848	99.95490935	985	99.80653604	965	86.56409769	819	0.949962683	0.219287271	normal	0.958854064	0.1904644	normal	0.976132963	-0.058386297	normal	0.602941301	0.120588554	normal	[C]	Energy production and conversion	Biological Process: ATP synthesis coupled proton transport (GO:0015986);; 	"K02134|1.13008e-91|ptr:742197|ATP5D; ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit; K02134 F-type H+-transporting ATPase subunit delta (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"ATP synthase, Delta/Epsilon chain, beta-sandwich domain"	"ATP synthase subunit delta, mitochondrial (Precursor) GN=ATP5D OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: ATP synthase subunit delta, mitochondrial [Bubalus bubalis]"
ENSG00000099625(CBARP)	--	2.334764948	144	1.687985	116	2.0841	144	1.999464633	122	2.248206118	142	1.676963646	109	0.940934935	-0.266921484	normal	0.939960913	0.267186846	normal	0.877027156	-0.405125819	normal	0.790355758	-0.136347941	normal	--	--	--	--	--	--	--	--	Protein Dos GN=DOS OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein Dos [Bubalus bubalis]
ENSG00000099769(IGFALS)	--	11.39254316	288	10.42684401	286	12.64425459	338	10.9849304	300	12.10380104	330	12.19839665	329	0.967377211	0.027915511	normal	0.948960015	0.184117392	normal	0.967510214	-0.047013888	normal	0.900377638	0.051915362	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K17256|0|hsa:3483|IGFALS, ACLSD, ALS; insulin-like growth factor binding protein, acid labile subunit; K17256 insulin-like growth factor-binding protein complex acid labile subunit (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Insulin-like growth factor-binding protein complex acid labile subunit (Precursor) GN=IGFALS OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: insulin-like growth factor-binding protein complex acid labile subunit [Ceratotherium simum simum]
ENSG00000099783(HNRNPM)	--	122.1657639	5208	129.097748	5797	125.271815	5503	151.5982401	6423	141.003733	5963	119.042301	5142	0.973189617	0.271613326	normal	0.993973157	0.019300329	normal	0.992073747	-0.106149976	normal	0.800365326	0.064634479	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12887|0|ptr:455671|HNRNPM, HNRPM; heterogeneous nuclear ribonucleoprotein M; K12887 heterogeneous nuclear ribonucleoprotein M (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Heterogeneous nuclear ribonucleoprotein M;; Limkain b1"	Heterogeneous nuclear ribonucleoprotein M GN=HNRNPM OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein M isoform X2 [Mustela putorius furo]
ENSG00000099785(MARCH2)	--	16.04557532	395	14.21380449	349	14.72136751	365	13.12179686	303	16.136437	366	13.566268	346	0.733947939	-0.411533295	normal	0.967012949	0.046991213	normal	0.965598461	-0.085053871	normal	0.624851727	-0.148522662	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10657|2.72618e-180|ptr:743428|MARCH2; membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase; K10657 E3 ubiquitin-protein ligase MARCH2 [EC:6.3.2.19] (A)"	--	[A]	RNA processing and modification	RING-variant domain	E3 ubiquitin-protein ligase MARCH2 GN=MARCH2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MARCH2 [Galeopterus variegatus]
ENSG00000099795(NDUFB7)	--	141.483	704	126.996	659	138.725	735	132.463	712	141.019	700	137.11	704	0.975438503	-0.014498987	normal	0.972636567	0.065504039	normal	0.973697237	-0.070312428	normal	0.984925516	-0.0087495	normal	--	--	Molecular Function: NADH dehydrogenase activity (GO:0003954);; Cellular Component: mitochondrion (GO:0005739);; Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; 	"K03963|3.12991e-75|hsa:4713|NDUFB7, B18, CI-B18; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa (EC:1.6.5.3 1.6.99.3); K03963 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 7 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 GN=NDUFB7 OS=Homo sapiens (Human) PE=1 SV=4	C	Energy production and conversion	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [Bos taurus] 
ENSG00000099797(TECR)	--	95.00341	1637	99.63446404	1716	92.81653	1623	83.737664	1465	92.750063	1585	102.082106	1794	0.968866519	-0.190796492	normal	0.978364897	-0.135868638	normal	0.97913052	0.136104779	normal	0.813067828	-0.059431167	normal	--	--	"Cellular Component: cytoplasm (GO:0005737);; Biological Process: lipid metabolic process (GO:0006629);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; "	"K10258|0|pps:100971383|TECR; trans-2,3-enoyl-CoA reductase; K10258 very-long-chain enoyl-CoA reductase [EC:1.3.1.93] (A)"	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	3-oxo-5-alpha-steroid 4-dehydrogenase	Very-long-chain enoyl-CoA reductase GN=TECR OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: very-long-chain enoyl-CoA reductase [Ailuropoda melanoleuca] 
ENSG00000099800(TIMM13)	--	28.238251	684	25.765912	758	31.3742869	774	38.8065597	887	42.5725	934	33.3355	731	0.840574056	0.343426514	normal	0.916695833	0.279295388	normal	0.972768892	-0.090571479	normal	0.391268349	0.182105974	normal	--	--	--	K17781|3.37542e-53|hgl:101702512|mitochondrial import inner membrane translocase subunit Tim13-like; K17781 mitochondrial import inner membrane translocase subunit TIM13 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim10/DDP family zinc finger	Mitochondrial import inner membrane translocase subunit Tim13 GN=TIMM13 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim13 [Galeopterus variegatus]
ENSG00000099804(CDC34)	--	40.36701043	1025	35.08044496	952	39.93105233	1103	39.29053004	1045	37.888101	998	37.51000976	998	0.979942903	-0.002948853	normal	0.977966217	0.046579415	normal	0.969872798	-0.152392754	normal	0.89168541	-0.039507796	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K02207|1.96698e-152|cfa:476759|CDC34; cell division cycle 34; K02207 ubiquitin-conjugating enzyme E2 R [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Herpes simplex infection (ko05168)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 R1 GN=CDC34 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 R1 [Canis lupus familiaris]
ENSG00000099810(MTAP)	--	3.957916485	148	4.357640604	186	4.635982536	165	4.724260454	192	5.334799018	185	5.036230561	212	0.89659446	0.341556567	normal	0.965600201	-0.02896775	normal	0.882648335	0.350466028	normal	0.568625124	0.218241923	normal	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: nucleoside metabolic process (GO:0009116);; 	K00772|0|pps:100974089|MTAP; methylthioadenosine phosphorylase; K00772 5'-methylthioadenosine phosphorylase [EC:2.4.2.28] (A)	Cysteine and methionine metabolism (ko00270)	[F]	Nucleotide transport and metabolism	Phosphorylase superfamily	S-methyl-5'-thioadenosine phosphorylase {ECO:0000255|HAMAP-Rule:MF_03155} OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: S-methyl-5'-thioadenosine phosphorylase [Ochotona princeps]
ENSG00000099812(MISP)	--	26.7477	1783	27.7595	1878	29.0623	1988	39.795	2650	42.2911	2803	38.3181	2571	0.194756129	0.540469146	normal	0.170621562	0.555979395	normal	0.856264608	0.362477305	normal	0.000877573	0.485226213	normal	--	--	--	--	--	--	--	A-kinase anchor protein 2 C-terminus	Mitotic interactor and substrate of PLK1 GN=MISP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitotic interactor and substrate of PLK1 [Galeopterus variegatus]
ENSG00000099814(CEP170B)	--	10.712381	1770	9.330420457	1599	10.18232921	1777	14.89720981	2451	14.34990069	2369	12.25986	2072	0.630952743	0.438464186	normal	0.197731141	0.545255517	normal	0.967540237	0.213120761	normal	0.008245446	0.399923236	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CEP170 C-terminus;; FHA domain	Centrosomal protein of 170 kDa protein B GN=CEP170B OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: centrosomal protein of 170 kDa protein B isoform 1 [Ceratotherium simum simum]
ENSG00000099817(POLR2E)	--	60.789686	1945	60.489277	2111	54.918592	1980	64.96562	2208	70.916261	2371	56.347863	1922	0.979871085	0.152024992	normal	0.981283727	0.146043766	normal	0.98596083	-0.051143887	normal	0.710853062	0.085491243	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K03013|2.48238e-143|ssc:100623333|POLR2E; polymerase (RNA) II (DNA directed) polypeptide E, 25kDa; K03013 DNA-directed RNA polymerases I, II, and III subunit RPABC1 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	"RNA polymerase Rpb5, C-terminal domain;; RNA polymerase Rpb5, N-terminal domain"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 GN=POLR2E OS=Homo sapiens (Human) PE=1 SV=4"	K	Transcription	"PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC1 [Ochotona princeps]"
ENSG00000099821(POLRMT)	--	24.624144	1735	20.803176	1528	22.86601576	1744	21.60911731	1537	19.68256008	1431	16.49187	1137	0.966324962	-0.205457296	normal	0.978889243	-0.115928839	normal	0.033926795	-0.624782994	normal	0.067177684	-0.30846141	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K10908|0|hsa:5442|POLRMT, APOLMT, MTRNAP, MTRPOL, h-mtRPOL; polymerase (RNA) mitochondrial (DNA directed) (EC:2.7.7.6); K10908 DNA-directed RNA polymerase, mitochondrial [EC:2.7.7.6] (A)"	--	[KL]	"Transcription;; Replication, recombination and repair"	DNA-dependent RNA polymerase;; DNA-directed RNA polymerase N-terminal	"DNA-directed RNA polymerase, mitochondrial (Precursor) GN=POLRMT OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: DNA-directed RNA polymerase, mitochondrial [Leptonychotes weddellii]"
ENSG00000099822(HCN2)	--	28.5974	1549	23.5594	1300	22.0922	1245	18.151	992	22.3516	1225	19.6032	1079	0.010993368	-0.672915772	normal	0.977593827	-0.107028145	normal	0.95687202	-0.214462236	normal	0.068841108	-0.333848749	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04955|0|hsa:610|HCN2, BCNG-2, BCNG2, HAC-1; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; K04955 hyperpolarization activated cyclic nucleotide-gated potassium channel 2 (A)"	cAMP signaling pathway (ko04024)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein N-terminal;; Cyclic nucleotide-binding domain;; Ion transport protein	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 GN=HCN2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 [Odobenus rosmarus divergens]
ENSG00000099834(CDHR5)	--	0.12873523	10	0.153460277	12	0.162926084	9	0.050802671	3	0.13538409	10	0.092414003	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16505|0|hsa:53841|CDHR5, MU-PCDH, MUCDHL, MUPCDH; cadherin-related family member 5; K16505 cadherin-related family member 5 (A)"	--	[S]	Function unknown	Cadherin domain	Cadherin-related family member 5 (Precursor) GN=CDHR5 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: cadherin-related family member 5 [Lipotes vexillifer]
ENSG00000099840(IZUMO4)	--	0.1863822	3	0.356087893	6	0.15247839	1	0.092460361	2	0.077378352	0	0.0563262	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Izumo sperm-egg fusion	Izumo sperm-egg fusion protein 4 (Precursor) GN=IZUMO4 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: izumo sperm-egg fusion protein 4 isoform 2 [Canis lupus familiaris]
ENSG00000099849(RASSF7)	--	19.96496083	625	24.07187987	759	20.930907	674	24.791419	764	20.23496401	624	23.070734	724	0.926085377	0.258309096	normal	0.892060731	-0.303312686	normal	0.971482775	0.094744517	normal	0.967635723	0.015835863	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	K09855|1.22763e-151|pps:100993969|RASSF7; Ras association (RalGDS/AF-6) domain family (N-terminal) member 7; K09855 Ras association domain-containing protein 7/8 (A)	--	[W]	Extracellular structures	Ras association (RalGDS/AF-6) domain	Ras association domain-containing protein 7 GN=RASSF7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ras association domain-containing protein 7 [Sus scrofa]
ENSG00000099860(GADD45B)	--	7.335688	182	8.726992155	214	10.17424285	293	18.431202	498	12.40025159	349	17.686769	426	1.21E-10	1.413867404	up	0.073115491	0.680389727	normal	0.360796068	0.529382569	normal	0.002423465	0.864532014	normal	--	--	--	"K04402|7.66339e-65|pon:100452809|GADD45B; growth arrest and DNA-damage-inducible, beta; K04402 growth arrest and DNA-damage-inducible protein (A)"	MAPK signaling pathway (ko04010);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115)	--	--	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	Growth arrest and DNA damage-inducible protein GADD45 beta GN=GADD45B OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: growth arrest and DNA damage-inducible protein GADD45 beta isoform X1 [Leptonychotes weddellii]
ENSG00000099864(PALM)	--	14.67947735	929	13.39202226	839	12.98820921	851	8.907792438	561	11.90770459	751	7.973743744	508	0.002129239	-0.756880758	normal	0.95920175	-0.180939523	normal	0.002917874	-0.750875471	normal	0.00332055	-0.546397517	normal	--	--	Biological Process: regulation of cell shape (GO:0008360);; Cellular Component: membrane (GO:0016020);; 	K16519|0|ggo:101133768|PALM; paralemmin-1; K16519 A-kinase anchor protein 2 (A)	--	--	--	Paralemmin	Paralemmin-1 (Precursor) GN=PALM OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: paralemmin-1 [Odobenus rosmarus divergens]
ENSG00000099866(MADCAM1)	--	0.572129458	11	0.7101	23	0.618458	20	0.339404542	7	0.238504	7	0.39040402	13	--	--	--	0.667744776	-1.54474948	normal	0.981534541	-0.575453989	normal	--	--	--	--	--	Biological Process: cell adhesion (GO:0007155);; Cellular Component: membrane (GO:0016020);; 	"K06779|5.76427e-107|hsa:8174|MADCAM1, MACAM1; mucosal vascular addressin cell adhesion molecule 1; K06779 mucosal vascular addressin cell adhesion molecule 1 (A)"	Cell adhesion molecules (CAMs) (ko04514);; Intestinal immune network for IgA production (ko04672)	--	--	"Adhesion molecule, immunoglobulin-like"	Mucosal addressin cell adhesion molecule 1 (Precursor) GN=MADCAM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: mucosal addressin cell adhesion molecule 1-like, partial [Leptonychotes weddellii]"
ENSG00000099875(MKNK2)	--	39.94074288	1370	35.51397448	1299	41.95197153	1310	40.8720477	1337	43.28451104	1533	41.79900525	1496	0.981505542	-0.065933836	normal	0.960009204	0.217296625	normal	0.968841609	0.183054041	normal	0.607456448	0.113073459	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K04372|0|pps:100978591|MKNK2; MAP kinase interacting serine/threonine kinase 2; K04372 MAP kinase interacting serine/threonine kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010);; HIF-1 signaling pathway (ko04066);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	MAP kinase-interacting serine/threonine-protein kinase 2 GN=MKNK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: MAP kinase-interacting serine/threonine-protein kinase 2 isoform X1 [Physeter catodon]
ENSG00000099889(ARVCF)	--	1.438550341	102	1.63245	107	1.48775733	112	1.659467706	117	1.395961649	88	1.2754669	91	0.962943696	0.164788271	normal	0.942082237	-0.29879703	normal	0.941259685	-0.303300011	normal	0.811979304	-0.138931206	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT-like repeat;; HEAT repeat;; Armadillo-like	Armadillo repeat protein deleted in velo-cardio-facial syndrome GN=ARVCF OS=Homo sapiens (Human) PE=1 SV=1	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: armadillo repeat protein deleted in velo-cardio-facial syndrome isoform X2 [Galeopterus variegatus]
ENSG00000099899(TRMT2A)	--	6.186526091	345	5.146408659	319	7.305	426	6.883076	387	7.072069903	389	7.463507457	444	0.960058985	0.134339875	normal	0.919072348	0.263653753	normal	0.96934149	0.051236632	normal	0.635174568	0.142242331	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: RNA processing (GO:0006396);; Molecular Function: RNA methyltransferase activity (GO:0008173);; 	K15332|0|pps:100984657|TRMT2A; tRNA methyltransferase 2 homolog A (S. cerevisiae); K15332 tRNA (uracil-5-)-methyltransferase [EC:2.1.1.-] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	"Methyltransferase domain;; tRNA (Uracil-5-)-methyltransferase;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)"	tRNA (uracil-5-)-methyltransferase homolog A GN=TRMT2A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: tRNA (uracil-5-)-methyltransferase homolog A [Myotis lucifugus]
ENSG00000099901(RANBP1)	--	104.2638987	1807	105.604973	1825	117.503247	2143	132.796492	2382	121.89795	2140	86.01261	1542	0.840965496	0.367471777	normal	0.969313367	0.208128373	normal	0.422940567	-0.482717071	normal	0.909344433	0.048339838	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular transport (GO:0046907);; 	K15306|4.05635e-172|nle:100587593|RANBP1; RAN binding protein 1; K15306 Ran-binding protein 1 (A)	HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain	Ran-specific GTPase-activating protein GN=RANBP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ran-specific GTPase-activating protein [Equus caballus]
ENSG00000099904(ZDHHC8)	--	17.17715673	745	15.2959998	634	14.85119455	646	19.60386915	754	19.97327764	735	19.79341619	771	0.97611058	-0.013480531	normal	0.954055395	0.191410507	normal	0.933500223	0.246376666	normal	0.566938018	0.137186265	normal	[R]	General function prediction only	--	"K18932|0|hsa:29801|ZDHHC8, DHHC8, ZDHHCL1, ZNF378; zinc finger, DHHC-type containing 8 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC8 GN=ZDHHC8 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC8 isoform X2 [Sus scrofa]
ENSG00000099910(KLHL22)	--	10.36211373	464	9.329819196	515	11.17643702	502	13.37137003	558	11.6377892	562	10.42033818	485	0.934806031	0.234598916	normal	0.966708411	0.104277958	normal	0.970213979	-0.057816847	normal	0.746492913	0.094461423	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10459|0|hsa:84861|KLHL22, KELCHL; kelch-like family member 22; K10459 kelch-like protein 22 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Kelch motif"	Kelch-like protein 22 GN=KLHL22 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 22 isoform 1 [Canis lupus familiaris]
ENSG00000099917(MED15)	--	15.95891419	1010	17.8066524	1096	19.14402386	1213	28.325281	1672	26.41388035	1563	21.2576897	1316	0.006223793	0.695556955	normal	0.399850586	0.490074456	normal	0.977855737	0.109157809	normal	0.004875079	0.433798329	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15157|4.8466e-175|nle:100584342|MED15; mediator complex subunit 15; K15157 mediator of RNA polymerase II transcription subunit 15 (A)	--	[K]	Transcription	ARC105 or Med15 subunit of Mediator complex non-fungal	Mediator of RNA polymerase II transcription subunit 15 GN=MED15 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 15 [Ursus maritimus]
ENSG00000099937(SERPIND1)	--	0.0403509	2	0.0276432	1	0	0	0.0820741	3	0.0266905	0	0.0271304	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K03912|0|hsa:3053|SERPIND1, D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10; serpin peptidase inhibitor, clade D (heparin cofactor), member 1; K03912 heparin cofactor II (A)"	Complement and coagulation cascades (ko04610)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Heparin cofactor 2 (Precursor) GN=SERPIND1 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: heparin cofactor 2 isoform X1 [Galeopterus variegatus]
ENSG00000099940(SNAP29)	--	9.70887	778	8.86577	708	9.45514	751	9.45644	756	9.79478	783	9.39498	755	0.974264948	-0.072071786	normal	0.968557822	0.123585302	normal	0.97632935	-0.000626447	normal	0.968742065	0.015168373	normal	--	--	--	"K08509|2.82983e-175|hsa:9342|SNAP29, CEDNIK, SNAP-29; synaptosomal-associated protein, 29kDa; K08509 synaptosomal-associated protein 29 (A)"	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain;; SNAP-25 family;; Snare region anchored in the vesicle membrane C-terminus	Synaptosomal-associated protein 29 GN=SNAP29 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptosomal-associated protein 29 [Canis lupus familiaris]
ENSG00000099942(CRKL)	--	13.0325	1174	14.7555	1334	14.4744	1300	15.1673	1368	15.554	1396	13.1888	1190	0.96549377	0.189573565	normal	0.982012322	0.044064884	normal	0.974812082	-0.135676466	normal	0.907191356	0.032764698	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K04438|0|ptr:470146|CRKL; v-crk avian sarcoma virus CT10 oncogene homolog-like; K04438 proto-oncogene C-crk (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Fc gamma R-mediated phagocytosis (ko04666);; Neurotrophin signaling pathway (ko04722);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Bacterial invasion of epithelial cells (ko05100);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Variant SH3 domain;; SH2 domain;; SH3 domain;; Variant SH3 domain	Crk-like protein GN=CRKL OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: crk-like protein [Tupaia chinensis] 
ENSG00000099949(LZTR1)	--	8.100983564	754	7.287135804	690	8.371123174	814	7.65680333	696	8.047994535	762	8.380836608	792	0.965335063	-0.145999704	normal	0.968458738	0.121514578	normal	0.976154004	-0.047729904	normal	0.939027777	-0.025665444	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; BTB/POZ domain;; Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; Recombination activating protein 2"	Leucine-zipper-like transcriptional regulator 1 GN=LZTR1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: leucine-zipper-like transcriptional regulator 1 isoform 1 [Trichechus manatus latirostris]
ENSG00000099953(MMP11)	--	0.050703406	2	0	0	0.0483344	1	0.227145749	9	0.866111	34	0.501091298	20	--	--	--	7.98E-07	4.54329417	up	0.026972074	3.092584572	normal	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K07993|0|hsa:4320|MMP11, SL-3, ST3, STMY3; matrix metallopeptidase 11 (stromelysin 3) (EC:3.4.24.-); K07993 matrix metalloproteinase-11 (stromelysin 3) [EC:3.4.24.-] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin	Stromelysin-3 (Precursor) GN=MMP11 OS=Homo sapiens (Human) PE=1 SV=3	OW	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	PREDICTED: stromelysin-3 [Pteropus alecto]
ENSG00000099954(CECR2)	--	0.124705901	21	0.131566463	20	0.025774161	4	0.01693354	3	0.024784477	3	0.050098787	8	0.160973546	-2.337186181	normal	0.234539251	-2.270316597	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[BK]	Chromatin structure and dynamics;; Transcription	Bromodomain	Cat eye syndrome critical region protein 2 GN=CECR2 OS=Homo sapiens (Human) PE=1 SV=2	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: LOW QUALITY PROTEIN: cat eye syndrome critical region protein 2 [Leptonychotes weddellii]
ENSG00000099956(SMARCB1)	--	21.66972746	757	23.30596983	827	23.53496757	851	23.48066497	844	28.18251614	1004	26.60525759	961	0.96969824	0.125875409	normal	0.932446774	0.257944821	normal	0.964900785	0.166806756	normal	0.369916765	0.185497964	normal	--	--	Cellular Component: nuclear chromosome (GO:0000228);; Biological Process: chromatin remodeling (GO:0006338);; 	K11648|0|xla:100505439|uncharacterized LOC100505439; K11648 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	SNF5 / SMARCB1 / INI1	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 GN=SMARCB1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 isoform X2 [Elephantulus edwardii]
ENSG00000099957(P2RX6)	--	1.4859803	109	1.630006731	94	1.729176604	117	0.263484096	16	0.223160864	11	0.194689394	14	4.54E-12	-2.685359436	down	6.69E-12	-2.952303185	down	3.34E-14	-2.941387638	down	4.21E-13	-2.985864002	down	--	--	Molecular Function: purinergic nucleotide receptor activity (GO:0001614);; Molecular Function: extracellular ATP-gated cation channel activity (GO:0004931);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: response to ATP (GO:0033198);; Biological Process: cation transmembrane transport (GO:0098655);; 	K05221|0|pps:100976042|P2RX6; P2X purinoceptor 6; K05221 P2X purinoceptor 6 (A)	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	--	--	ATP P2X receptor	P2X purinoceptor 6 GN=P2RX6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: P2X purinoceptor 6 isoform X2 [Oryctolagus cuniculus]
ENSG00000099958(DERL3)	--	0.174151404	4	0.152913754	5	0.227421	2	0.319732501	8	0.271965904	5	0.145426401	4	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	K13989|1.02363e-135|ptr:747196|DERL3; derlin 3; K13989 Derlin-2/3 (A)	Protein processing in endoplasmic reticulum (ko04141)	[S]	Function unknown	Der1-like family	Derlin-3 GN=DERL3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: derlin-3 [Sorex araneus]
ENSG00000099960(SLC7A4)	--	0.056678849	2	0.1126837	4	0	0	0.028455295	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13866|0|hsa:6545|SLC7A4, CAT-4, CAT4, HCAT3, VH; solute carrier family 7, member 4; K13866 solute carrier family 7 (cationic amino acid transporter), member 4 (A)"	--	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease;; C-terminus of AA_permease	Cationic amino acid transporter 4 GN=SLC7A4 OS=Homo sapiens (Human) PE=2 SV=3	E	Amino acid transport and metabolism	PREDICTED: cationic amino acid transporter 4 [Oryctolagus cuniculus] 
ENSG00000099968(BCL2L13)	--	12.61307224	838	13.09504446	883	13.57965162	896	16.4635279	1127	17.33480953	1183	17.96874585	1254	0.730495883	0.396005071	normal	0.732238651	0.39994451	normal	0.434170957	0.475993089	normal	0.007520927	0.424784312	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K15485|0|hsa:23786|BCL2L13, BCL-RAMBO, Bcl2-L-13, MIL1; BCL2-like 13 (apoptosis facilitator); K15485 Bcl-2-like protein 13 (A)"	Legionellosis (ko05134)	--	--	"Apoptosis regulator proteins, Bcl-2 family"	Bcl-2-like protein 13 GN=BCL2L13 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bcl-2-like protein 13 isoform X1 [Panthera tigris altaica] 
ENSG00000099974(DDTL)	--	1.2823	35	1.89325	52	1.4677	40	1.17014	32	1.03259	28	1.01485	28	0.982565524	-0.153084128	normal	0.706489137	-0.879129299	normal	0.960348851	-0.500150653	normal	0.390965648	-0.55112053	normal	--	--	--	--	--	[V]	Defense mechanisms	Macrophage migration inhibitory factor (MIF)	D-dopachrome decarboxylase-like protein GN=DDTL OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: D-dopachrome decarboxylase-like [Tupaia chinensis] 
ENSG00000099977(DDT)	--	73.08333685	556	64.04311761	503	77.25588413	608	81.96024491	613	58.778992	453	76.05170009	582	0.96766555	0.109681211	normal	0.954426286	-0.171928908	normal	0.971418964	-0.07116268	normal	0.910974783	-0.037752944	normal	--	--	--	K10028|2.69087e-63|ptr:747265|DDT; D-dopachrome tautomerase; K10028 D-dopachrome decarboxylase [EC:4.1.1.84] (A)	--	[V]	Defense mechanisms	Macrophage migration inhibitory factor (MIF)	D-dopachrome decarboxylase GN=DDT OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: D-dopachrome decarboxylase-like [Tupaia chinensis] 
ENSG00000099985(OSM)	--	0.029461593	1	0.028662103	1	0.028081235	0	0.029380857	1	0	0	0.116045286	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; 	K05418|1.8318e-171|hsa:5008|OSM; oncostatin M; K05418 oncostatin M (A)	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630)	--	--	LIF / OSM family	Oncostatin-M (Precursor) GN=OSM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oncostatin-M [Odobenus rosmarus divergens]
ENSG00000099991(CABIN1)	--	11.15214045	1623	12.07773417	1554	10.7639768	1604	8.473193355	1315	8.485855152	1369	10.32410013	1559	0.876206087	-0.334080336	normal	0.964457594	-0.204078849	normal	0.98388965	-0.049297509	normal	0.300465686	-0.192882682	normal	--	--	--	"K17613|0|hsa:23523|CABIN1, CAIN, PPP3IN; calcineurin binding protein 1; K17613 calcineurin-binding protein cabin-1 (A)"	--	--	--	MEF2 binding;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Calcineurin-binding protein cabin-1 GN=CABIN1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: calcineurin-binding protein cabin-1 [Canis lupus familiaris]
ENSG00000099992(TBC1D10A)	--	20.0229121	613	14.96661297	486	16.9979003	551	10.13860567	357	8.58401067	296	7.74066046	263	0.001340363	-0.808106398	normal	0.013911721	-0.733828193	normal	2.02E-06	-1.070928197	down	1.85E-06	-0.871141561	normal	[R]	General function prediction only	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	TBC1 domain family member 10A GN=TBC1D10A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 10A isoform X1 [Ochotona princeps]
ENSG00000099994(SUSD2)	--	31.351724	2223	13.5708831	963	17.608801	1271	1.893953926	132	2.422016	170	3.719567191	265	0	-4.088843191	down	0	-2.512802964	down	0	-2.263668619	down	0.000382316	-2.9939731	down	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: immune response (GO:0006955);; Molecular Function: polysaccharide binding (GO:0030247);; 	--	--	[W]	Extracellular structures	AMOP domain;; von Willebrand factor type D domain;; Sushi domain (SCR repeat);; Somatomedin B domain	Sushi domain-containing protein 2 (Precursor) GN=SUSD2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: sushi domain-containing protein 2 [Galeopterus variegatus]
ENSG00000099995(SF3A1)	--	18.23960996	1931	17.63707362	1870	18.3110795	1983	19.7982024	2054	19.72301372	2080	15.71695502	1685	0.98593314	0.058210844	normal	0.981086743	0.132017437	normal	0.956756867	-0.243026231	normal	0.971095564	-0.012925018	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; Biological Process: RNA processing (GO:0006396);; 	"K12825|0|pps:100971985|SF3A1; splicing factor 3a, subunit 1, 120kDa; K12825 splicing factor 3A subunit 1 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Pre-mRNA splicing factor PRP21 like protein;; Surp module;; Ubiquitin family	Splicing factor 3A subunit 1 GN=SF3A1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: splicing factor 3A subunit 1 [Ursus maritimus]
ENSG00000099998(GGT5)	--	0.831779854	4	2.057230017	8	0.747803012	2	2.125478597	15	2.663836251	29	4.415024974	30	--	--	--	0.316596534	1.662334362	normal	0.000466589	3.159124861	up	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: glutathione catabolic process (GO:0006751);; Molecular Function: glutathione hydrolase activity (GO:0036374);; 	"K18592|0|hsa:2687|GGT5, GGL, GGT_5, GGT-REL, GGTLA1; gamma-glutamyltransferase 5 (EC:2.3.2.2 3.4.19.13 3.4.19.14); K18592 gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14] (A)"	Taurine and hypotaurine metabolism (ko00430);; Cyanoamino acid metabolism (ko00460);; Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590)	[E]	Amino acid transport and metabolism	Gamma-glutamyltranspeptidase	Gamma-glutamyltransferase 5 light chain (Precursor) GN=GGT5 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: gamma-glutamyltransferase 5 isoform X1 [Galeopterus variegatus]
ENSG00000099999(RNF215)-2	--	1.22117	6	0.194429	1	0.189418	0	0.379768	2	1.78738	8	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000099999(RNF215)-3	--	21.02432339	635	18.9546501	551	17.5298618	538	14.7771302	441	13.57611409	383	12.33633012	379	0.196793108	-0.555188342	normal	0.267909561	-0.544331945	normal	0.368342867	-0.511976119	normal	0.003867524	-0.540954319	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000100003(SEC14L2)	--	27.80928799	714	31.727382	863	32.47384	898	35.44435369	1027	32.72909163	943	30.07265791	699	0.368313028	0.492719605	normal	0.973132542	0.106292431	normal	0.79401281	-0.369008154	normal	0.818933121	0.086803693	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	"CRAL/TRIO domain;; Golgi-dynamics membrane-trafficking;; CRAL/TRIO, N-terminal domain;; Divergent CRAL/TRIO domain"	SEC14-like protein 2 GN=SEC14L2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: SEC14-like protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000100014(SPECC1L)	--	8.890374924	1312	11.55671537	1520	9.962910961	1468	9.874753454	1456	10.22399114	1460	9.835138009	1452	0.978021312	0.119277743	normal	0.98156419	-0.079448851	normal	0.983618818	-0.024077017	normal	1	0.001479752	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Calponin homology (CH) domain;; CAMSAP CH domain	Cytospin-A GN=SPECC1L OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: cytospin-A isoform X1 [Pteropus alecto] 
ENSG00000100023(PPIL2)	--	10.62783434	726	11.80220541	715	10.31881424	713	9.925491241	673	10.54154162	703	10.1319471	709	0.965847657	-0.139887714	normal	0.974114713	-0.045747526	normal	0.975558697	-0.016373066	normal	0.812310235	-0.068004058	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K10598|0|hsa:23759|PPIL2, CYC4, CYP60, Cyp-60, UBOX7, hCyP-60; peptidylprolyl isomerase (cyclophilin)-like 2 (EC:5.2.1.8); K10598 peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD;; Rtf2 RING-finger	Peptidyl-prolyl cis-trans isomerase-like 2 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidylprolyl isomerase (cyclophilin)-like 2 isoform X2 [Canis lupus familiaris]
ENSG00000100024(UPB1)	--	0	0	0.0849301	4	0	0	0	0	0	0	0.021511	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; "	"K01431|0|ptr:747532|UPB1; ureidopropionase, beta; K01431 beta-ureidopropionase [EC:3.5.1.6] (A)"	Pyrimidine metabolism (ko00240);; beta-Alanine metabolism (ko00410);; Pantothenate and CoA biosynthesis (ko00770);; Drug metabolism - other enzymes (ko00983)	[E]	Amino acid transport and metabolism	Carbon-nitrogen hydrolase	Beta-ureidopropionase GN=UPB1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: beta-ureidopropionase [Panthera tigris altaica]
ENSG00000100027(YPEL1)	--	0.783674	59	0.671762	51	1.116827	41	0.806556	61	0.693311	52	1.007914	62	0.976858237	0.016830979	normal	0.977331881	0.006399883	normal	0.902176054	0.571110581	normal	0.792510083	0.191128791	normal	--	--	--	--	--	[R]	General function prediction only	"Yippee zinc-binding/DNA-binding /Mis18, centromere assembly"	Protein yippee-like 1 GN=YPEL1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	protein yippee-like 1 [Bos taurus] 
ENSG00000100028(SNRPD3)	--	35.92324	1210	36.02734	1234	38.65814	1195	52.3515	1552	47.921	1573	40.65201	1313	0.881822013	0.327920806	normal	0.885625012	0.328392502	normal	0.975896246	0.127410982	normal	0.124474414	0.264692612	normal	[K]	Transcription	--	K11088|1.03974e-78|xtr:549847|snrpd3; small nuclear ribonucleoprotein D3 polypeptide 18kDa; K11088 small nuclear ribonucleoprotein D3 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	Small nuclear ribonucleoprotein Sm D3 GN=SNRPD3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: small nuclear ribonucleoprotein Sm D3 isoform X1 [Tupaia chinensis]
ENSG00000100029(PES1)	--	42.51035133	2193	44.75494703	2327	48.15694497	2503	46.49308208	2338	44.2880403	2252	38.2628073	1944	0.987050211	0.061495126	normal	0.986595871	-0.068645589	normal	0.835065163	-0.372665314	normal	0.549153652	-0.125659264	normal	[J]	"Translation, ribosomal structure and biogenesis"	Cellular Component: nucleolus (GO:0005730);; Biological Process: ribosome biogenesis (GO:0042254);; 	K14843|0|ptr:458759|PES1; pescadillo ribosomal biogenesis factor 1; K14843 pescadillo (A)	--	[A]	RNA processing and modification	Pescadillo N-terminus;; BRCA1 C Terminus (BRCT) domain	Pescadillo homolog {ECO:0000255|HAMAP-Rule:MF_03028} OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pescadillo homolog isoform X1 [Panthera tigris altaica]
ENSG00000100030(MAPK1)	--	32.942577	2796	37.58596735	2874	36.21293695	2734	34.15970159	2919	31.40867129	2800	32.58764215	2706	0.98967004	0.031260774	normal	0.988783131	-0.059028323	normal	0.989374594	-0.023129985	normal	0.956591116	-0.017888393	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04371|0|ptr:458680|MAPK1; mitogen-activated protein kinase 1; K04371 mitogen-activated protein kinase 1/3 [EC:2.7.11.24] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Dorso-ventral axis formation (ko04320);; TGF-beta signaling pathway (ko04350);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Aldosterone-regulated sodium reabsorption (ko04960);; Alzheimer's disease (ko05010);; Prion diseases (ko05020);; Alcoholism (ko05034);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase 1 GN=MAPK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 1 isoform X1 [Sorex araneus]
ENSG00000100031(GGT1)	--	32.63978	1176	36.16691474	1201	37.03561246	1223	49.99178948	1690	53.677	1859	59.12499906	1939	0.369131342	0.491764389	normal	0.058027769	0.608243905	normal	0.016026656	0.655947226	normal	4.13E-05	0.587574033	normal	[E]	Amino acid transport and metabolism	Biological Process: glutathione catabolic process (GO:0006751);; Molecular Function: glutathione hydrolase activity (GO:0036374);; 	"K18592|0|hsa:2678|GGT1, CD224, D22S672, D22S732, GGT, GGT_1, GTG; gamma-glutamyltransferase 1 (EC:2.3.2.2 3.4.19.13 3.4.19.14); K18592 gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14] (A)"	Taurine and hypotaurine metabolism (ko00430);; Cyanoamino acid metabolism (ko00460);; Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590)	[E]	Amino acid transport and metabolism	Gamma-glutamyltranspeptidase	Gamma-glutamyltranspeptidase 1 light chain (Precursor) GN=GGT1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: gamma-glutamyltranspeptidase 1 [Camelus dromedarius]
ENSG00000100033(PRODH)	--	0.360531	2	0	0	0	0	0.242337	1	0.0239468	0	0.4513873	3	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	--	"K00318|0|hsa:102724788|proline dehydrogenase 1, mitochondrial-like; K00318 proline dehydrogenase [EC:1.5.-.-] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	Proline dehydrogenase	"Proline dehydrogenase 1, mitochondrial (Precursor) GN=PRODH OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: proline dehydrogenase 1, mitochondrial isoform X1 [Felis catus]"
ENSG00000100034(PPM1F)	--	10.11750204	953	10.71329232	957	10.95912794	1066	11.44679155	1096	10.6328787	915	10.17986686	899	0.965967191	0.170610784	normal	0.975345552	-0.086034682	normal	0.936142051	-0.253713416	normal	0.845329298	-0.054003564	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K17502|0|hsa:9647|PPM1F, CAMKP, CaMKPase, FEM-2, POPX2, hFEM-2; protein phosphatase, Mg2+/Mn2+ dependent, 1F (EC:3.1.3.16); K17502 protein phosphatase 1F [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C;; Protein phosphatase 2C	Protein phosphatase 1F GN=PPM1F OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1F [Galeopterus variegatus]
ENSG00000100036(SLC35E4)	--	3.85652492	196	3.12985593	161	3.1898217	169	3.284041	170	3.1926315	144	2.0292161	106	0.941583789	-0.234177966	normal	0.954356996	-0.180623344	normal	0.311584736	-0.673570507	normal	0.333968763	-0.347289246	normal	--	--	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K15286|1.19756e-179|pps:100980940|SLC35E4; solute carrier family 35, member E4; K15286 solute carrier family 35, member E4 (A)"	--	--	--	Triose-phosphate Transporter family;; EamA-like transporter family;; UAA transporter family	Solute carrier family 35 member E4 GN=SLC35E4 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 35 member E4 [Vicugna pacos]
ENSG00000100038(TOP3B)	--	9.869336634	400	4.858807665	351	5.81448604	341	7.42962552	372	6.061741291	390	10.41567639	496	0.960309443	-0.134991786	normal	0.959936806	0.130044823	normal	0.322197564	0.530315875	normal	0.508741962	0.183684206	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase activity (GO:0003916);; Biological Process: DNA topological change (GO:0006265);; 	"K03165|0|hsa:8940|TOP3B, TOP3B1; topoisomerase (DNA) III beta (EC:5.99.1.2); K03165 DNA topoisomerase III [EC:5.99.1.2] (A)"	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	DNA topoisomerase;; Toprim domain	DNA topoisomerase 3-beta-1 GN=TOP3B OS=Homo sapiens (Human) PE=2 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA topoisomerase 3-beta-1 isoform X1 [Equus caballus] 
ENSG00000100053(CRYBB3)	--	0	0	0.076311	1	0	0	0	0	0.138782	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Beta/Gamma crystallin	"Beta-crystallin B3, N-terminally processed GN=CRYBB3 OS=Homo sapiens (Human) PE=1 SV=4"	R	General function prediction only	PREDICTED: beta-crystallin B3 [Panthera tigris altaica]
ENSG00000100055(CYTH4)	--	0.176059936	8	0.040409329	2	0.084967168	4	0.219790395	13	0.498027642	18	0.24238455	12	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K18441|0|hsa:27128|CYTH4, CYT4, DJ63G5.1, PSCD4; cytohesin 4; K18441 cytohesin (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; PH domain	Cytohesin-4 GN=CYTH4 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: cytohesin-4 [Trichechus manatus latirostris]
ENSG00000100056(DGCR14)	--	2.358160281	277	1.750200402	210	1.806399711	217	1.968187166	231	2.597563697	303	2.195064496	258	0.909430567	-0.291054599	normal	0.548785716	0.504462206	normal	0.93522591	0.239849849	normal	0.677267823	0.149020991	normal	--	--	--	"K13118|0|hsa:8220|DGCR14, DGCR13, DGS-H, DGS-I, DGSH, DGSI, ES2, Es2el; DiGeorge syndrome critical region gene 14; K13118 protein DGCR14 (A)"	--	[R]	General function prediction only	Nuclear protein Es2	Protein DGCR14 GN=DGCR14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein DGCR14 [Leptonychotes weddellii]
ENSG00000100060(MFNG)	--	0.256479197	7	1.377361824	25	0.207405949	6	1.130157805	37	1.332305502	27	0.947710135	27	0.008282504	2.147071159	up	0.985214744	0.084675394	normal	0.183642172	1.91702269	normal	0.057698005	1.235882695	normal	--	--	"Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	K05948|0|pps:100995551|MFNG; MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; K05948 fringe [EC:2.4.1.222] (A)	Other types of O-glycan biosynthesis (ko00514);; Notch signaling pathway (ko04330)	--	--	Fringe-like	"Beta-1,3-N-acetylglucosaminyltransferase manic fringe GN=MFNG OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-N-acetylglucosaminyltransferase manic fringe [Ailuropoda melanoleuca]"
ENSG00000100065(CARD10)	--	6.421395733	551	4.869947203	439	7.15413165	607	13.83445606	1200	12.62423722	1084	8.262347006	711	5.04E-08	1.089969145	up	1.15E-10	1.279747031	up	0.944638399	0.219356159	normal	0.014298742	0.884994568	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	--	--	--	--	Caspase recruitment domain	Caspase recruitment domain-containing protein 10 GN=CARD10 OS=Homo sapiens (Human) PE=2 SV=2	F	Nucleotide transport and metabolism	PREDICTED: caspase recruitment domain-containing protein 10 [Vicugna pacos]
ENSG00000100068(LRP5L)	--	2.87562015	164	2.870498358	165	3.689273502	215	2.177610179	129	2.8533085	181	2.827770606	174	0.885935146	-0.373203878	normal	0.961524105	0.11112446	normal	0.907797603	-0.311103629	normal	0.64086654	-0.18834389	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor repeat class B	Low-density lipoprotein receptor-related protein 5-like protein GN=LRP5L OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 5-like protein [Galeopterus variegatus]
ENSG00000100075(SLC25A1)	--	80.03864	2276	61.18573	1778	80.64432	2360	64.76093	1850	66.79056	1899	81.73962	2344	0.898535409	-0.329560259	normal	0.984193285	0.073497529	normal	0.988236601	-0.018094098	normal	0.773944744	-0.094234011	normal	--	--	--	"K15100|2.69694e-180|ptr:458647|SLC25A1; solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1; K15100 solute carrier family 25 (mitochondrial citrate transporter), member 1 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	"Tricarboxylate transport protein, mitochondrial (Precursor) GN=SLC25A1 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: tricarboxylate transport protein, mitochondrial [Oryctolagus cuniculus]"
ENSG00000100077(GRK3)	--	3.044935749	390	2.849813536	353	3.280394937	350	1.948753206	275	1.910887385	281	2.086140553	251	0.36798502	-0.532363042	normal	0.850327321	-0.348845524	normal	0.557067914	-0.485470305	normal	0.04758113	-0.459161011	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K00910|0|pps:100984800|ADRBK2; adrenergic, beta, receptor kinase 2; K00910 beta-adrenergic-receptor kinase [EC:2.7.11.15] (A)"	Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Glutamatergic synapse (ko04724);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Regulator of G protein signaling domain;; PH domain	Beta-adrenergic receptor kinase 2 GN=ADRBK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: beta-adrenergic receptor kinase 2 [Oryctolagus cuniculus]
ENSG00000100083(GGA1)	--	13.7140211	647	9.477750997	540	10.43279102	542	9.31944657	540	11.57038722	579	14.024795	687	0.900152689	-0.290881205	normal	0.969431888	0.078963799	normal	0.854645496	0.332898948	normal	0.900052149	0.042271927	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K12404|0|mcf:102128394|GGA1; golgi-associated, gamma adaptin ear containing, ARF binding protein 1; K12404 ADP-ribosylation factor-binding protein GGA (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	VHS domain;; GAT domain;; Adaptin C-terminal domain	ADP-ribosylation factor-binding protein GGA1 GN=GGA1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-binding protein GGA1 isoform X1 [Leptonychotes weddellii]
ENSG00000100084(HIRA)	--	7.941163159	677	8.36014227	726	8.455541407	733	10.70764473	913	11.19169018	945	10.58450437	903	0.716899169	0.399842881	normal	0.821397103	0.358262447	normal	0.904614806	0.2920775	normal	0.046705984	0.349146213	normal	[R]	General function prediction only	"Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K11293|0|hsa:7290|HIRA, DGCR1, TUP1, TUPLE1; histone cell cycle regulator; K11293 protein HIRA/HIR1 (A)"	--	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	"TUP1-like enhancer of split;; WD domain, G-beta repeat;; HIRA B motif"	Protein HIRA GN=HIRA OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: protein HIRA [Oryctolagus cuniculus]
ENSG00000100092(SH3BP1)	--	2.717523625	172	1.94738782	124	2.529802	154	1.459716162	91	2.163268	134	0.6774046	42	0.012156293	-0.937584677	normal	0.965103817	0.089417142	normal	5.50E-09	-1.84564083	down	0.123402939	-0.775436452	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; BAR domain	SH3 domain-binding protein 1 GN=SH3BP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SH3 domain-binding protein 1 [Galeopterus variegatus]
ENSG00000100097(LGALS1)	--	926.897	5322	752.134	4393	931.274	5554	1360.32	8275	1156.72	6638	772.388	4572	0.081937831	0.605817249	normal	0.170165686	0.573953779	normal	0.963831057	-0.288906368	normal	0.459142896	0.329130375	normal	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	"K06830|2.1248e-95|ptr:742148|LGALS1; lectin, galactoside-binding, soluble, 1; K06830 galectin-1 (A)"	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-1 GN=LGALS1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: galectin-1 [Camelus bactrianus]
ENSG00000100099(HPS4)	--	6.457511602	511	7.34103906	590	7.02128526	555	7.274079598	581	7.399545	570	8.739210437	685	0.960219526	0.153948314	normal	0.970415961	-0.070994441	normal	0.8978046	0.294600956	normal	0.624077398	0.128131298	normal	--	--	--	--	--	--	--	--	Hermansky-Pudlak syndrome 4 protein GN=HPS4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: Hermansky-Pudlak syndrome 4 protein [Galeopterus variegatus]
ENSG00000100100(PIK3IP1)	--	1.378285171	55	1.63225635	77	1.488710964	72	3.4048263	134	3.646681466	172	2.153813866	102	0.000839412	1.23118873	up	0.000845074	1.122920622	up	0.868037288	0.48559912	normal	0.009266599	0.978384011	normal	--	--	--	--	--	--	--	Kringle domain	Phosphoinositide-3-kinase-interacting protein 1 (Precursor) GN=PIK3IP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphoinositide-3-kinase-interacting protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000100104(SRRD)	--	2.52599	183	2.8381	207	2.40423	174	3.16791	231	3.67485	266	2.94034	214	0.909863694	0.302948968	normal	0.877081315	0.338184457	normal	0.920167772	0.28797146	normal	0.3188535	0.31261532	normal	--	--	--	--	--	[S]	Function unknown	SRR1	SRR1-like protein GN=SRRD OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SRR1-like protein [Ceratotherium simum simum]
ENSG00000100105(PATZ1)	--	14.61389506	779	14.993463	822	12.45817946	695	14.416405	778	14.326307	775	14.526091	786	0.976196167	-0.032621057	normal	0.971495794	-0.106167442	normal	0.961356979	0.16887915	normal	0.989936683	0.00535307	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc finger, C2H2 type;; BTB/POZ domain;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	"POZ-, AT hook-, and zinc finger-containing protein 1 GN=PATZ1 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: POZ-, AT hook-, and zinc finger-containing protein 1 isoform X1 [Galeopterus variegatus]"
ENSG00000100106(TRIOBP)	--	28.62402401	1632	25.93366479	1459	25.56916607	1520	20.522961	1262	23.82225506	1416	19.214065	1177	0.731463891	-0.401330374	normal	0.981871699	-0.06451729	normal	0.794050091	-0.376821186	normal	0.098166993	-0.279665456	normal	--	--	--	--	--	[Z]	Cytoskeleton	PH domain	TRIO and F-actin-binding protein GN=TRIOBP OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: TRIO and F-actin-binding protein [Equus caballus]
ENSG00000100109(TFIP11)	--	8.81020223	613	7.960764202	568	8.490062517	646	9.450006326	690	9.581279672	720	9.231041298	673	0.96493467	0.139547234	normal	0.873433561	0.319921338	normal	0.973715202	0.05066469	normal	0.472013956	0.168133034	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K13103|0|pps:100981317|TFIP11; tuftelin interacting protein 11; K13103 tuftelin-interacting protein 11 (A)	--	[A]	RNA processing and modification	GC-rich sequence DNA-binding factor-like protein;; Tuftelin interacting protein N terminal;; G-patch domain	Tuftelin-interacting protein 11 GN=TFIP11 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: tuftelin-interacting protein 11 [Galeopterus variegatus]
ENSG00000100116(GCAT)	--	1.209843097	32	0.893812034	24	1.1451412	32	2.321143036	60	1.904415916	49	2.92944456	77	0.682473523	0.845969681	normal	0.650414257	0.964971367	normal	0.033699976	1.220203769	normal	0.029304733	1.059525045	normal	[H]	Coenzyme transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00639|0|hsa:23464|GCAT, KBL; glycine C-acetyltransferase (EC:2.3.1.29); K00639 glycine C-acetyltransferase [EC:2.3.1.29] (A)"	"Glycine, serine and threonine metabolism (ko00260)"	[E]	Amino acid transport and metabolism	Aminotransferase class I and II;; Aminotransferase class-V	"2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial (Precursor) GN=GCAT OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial [Physeter catodon]"
ENSG00000100124(ANKRD54)	--	12.40538447	435	9.231957	349	11.09217431	438	12.90303657	449	15.88979898	502	11.55826334	415	0.970456288	0.014816272	normal	0.437118739	0.501213803	normal	0.966932852	-0.085806567	normal	0.624790986	0.139623411	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 54 GN=ANKRD54 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 54 isoformX1 [Canis lupus familiaris]
ENSG00000100129(EIF3L)	--	126.77738	4968	114.4644992	4426	109.4092677	4251	98.9995024	3852	106.278991	4112	112.71538	4447	0.836637105	-0.397749597	normal	0.989362257	-0.127544518	normal	0.992140001	0.056718974	normal	0.430925855	-0.157653186	normal	--	--	Molecular Function: translation initiation factor activity (GO:0003743);; Cellular Component: cytoplasm (GO:0005737);; Cellular Component: eukaryotic translation initiation factor 3 complex (GO:0005852);; 	"K15029|0|pps:100971360|EIF3L; eukaryotic translation initiation factor 3, subunit L; K15029 translation initiation factor 3 subunit L (A)"	--	[JK]	"Translation, ribosomal structure and biogenesis;; Transcription"	RNA polymerase I-associated factor PAF67	Eukaryotic translation initiation factor 3 subunit L {ECO:0000255|HAMAP-Rule:MF_03011} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: eukaryotic translation initiation factor 3 subunit L [Mustela putorius furo]
ENSG00000100138(SNU13)	--	47.79764236	1032	47.58222963	1065	61.7354765	1191	58.3274146	1198	48.65147892	1068	42.21278562	935	0.964438898	0.184098121	normal	0.979735554	-0.017343748	normal	0.825585734	-0.356913793	normal	0.821676867	-0.06039845	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: rRNA processing (GO:0006364);; Biological Process: tRNA processing (GO:0008033);; 	K12845|2.20197e-65|lve:103089777|NHP2L1; NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae); K12845 U4/U6 small nuclear ribonucleoprotein SNU13 (A)	Ribosome biogenesis in eukaryotes (ko03008);; Spliceosome (ko03040)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family;; RNase P subunit Pop3	"NHP2-like protein 1, N-terminally processed GN=NHP2L1 OS=Homo sapiens (Human) PE=1 SV=3"	A	RNA processing and modification	NHP2-like protein 1 isoform 3 [Camelus ferus]
ENSG00000100139(MICALL1)	--	10.77650581	973	9.345228199	930	8.979084073	896	14.14404043	1243	12.93264545	1139	16.45507229	1160	0.880768092	0.322031496	normal	0.927749489	0.270640324	normal	0.811102346	0.363721761	normal	0.060396904	0.318130209	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Protein of unknown function (DUF3585);; Calponin homology (CH) domain;; CAMSAP CH domain;; LIM domain	MICAL-like protein 1 GN=MICALL1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: MICAL-like protein 1 [Leptonychotes weddellii]
ENSG00000100142(POLR2F)	--	34.6969011	538	41.3653549	598	42.3801759	667	50.0895254	715	38.230242	607	40.2345508	622	0.772779891	0.37856434	normal	0.973092413	0.000124163	normal	0.969076094	-0.108808095	normal	0.754702634	0.087232278	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K03014|9.42447e-36|ssc:100524934|DNA-directed RNA polymerases I, II, and III subunit RPABC2-like; K03014 DNA-directed RNA polymerases I, II, and III subunit RPABC2 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpb6	"DNA-directed RNA polymerases I, II, and III subunit RPABC2 GN=POLR2F OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC2 isoform X2 [Galeopterus variegatus]"
ENSG00000100146(SOX10)	--	0.016529927	1	0.065251495	4	0.01582655	0	0.016620255	1	0.0465759	0	0.079389494	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K09270|0|hsa:6663|SOX10, DOM, PCWH, WS2E, WS4, WS4C; SRY (sex determining region Y)-box 10; K09270 transcription factor SOX7/8/10/18 (SOX group E/F) (A)"	--	[K]	Transcription	Sox developmental protein N terminal;; HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-10 GN=SOX10 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: transcription factor SOX-10 [Myotis lucifugus]
ENSG00000100147(CCDC134)	--	2.718554001	359	3.324395	414	3.2168407	398	2.908877	382	3.031034644	396	2.496381364	329	0.967559024	0.058513752	normal	0.965645866	-0.085238494	normal	0.908344851	-0.281792747	normal	0.753252589	-0.102631566	normal	--	--	--	--	--	--	--	"ERK and JNK pathways, inhibitor"	Coiled-coil domain-containing protein 134 (Precursor) GN=CCDC134 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 134 [Loxodonta africana]
ENSG00000100150(DEPDC5)	--	2.095208989	200	1.70993809	157	2.285714295	223	2.205524708	175	1.513409118	167	1.479062743	169	0.944514604	-0.221655238	normal	0.964733632	0.067030907	normal	0.821344604	-0.405145445	normal	0.598083532	-0.20357775	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	"Protein of unknown function (DUF3608);; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	DEP domain-containing protein 5 GN=DEPDC5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DEP domain-containing protein 5 isoform 1 [Ceratotherium simum simum]
ENSG00000100151(PICK1)	--	8.16607127	254	7.111475923	297	6.466424582	245	8.835537216	287	8.77588555	290	8.646266331	334	0.957571653	0.144566985	normal	0.965410051	-0.055550329	normal	0.703865369	0.436458719	normal	0.586559751	0.173697598	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: protein domain specific binding (GO:0019904);; 	--	--	[T]	Signal transduction mechanisms	Arfaptin-like domain;; PDZ domain (Also known as DHR or GLGF);; BAR domain	PRKCA-binding protein GN=PICK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: PRKCA-binding protein isoform X1 [Mustela putorius furo] 
ENSG00000100154(TTC28)	--	4.6171557	910	3.93038	884	3.48523521	816	4.246503	953	3.593815	843	5.152972	1217	0.978231541	0.035718475	normal	0.97400827	-0.08978299	normal	0.119787558	0.567529851	normal	0.542395782	0.186489053	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; CHAT domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Rapsyn N-terminal myristoylation and linker region;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 28 GN=TTC28 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: tetratricopeptide repeat protein 28 [Equus caballus]
ENSG00000100156(SLC16A8)	--	0.488767	11	0.42204	10	0.245816	5	0.129272	3	0.683958	15	0.780268	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08185|0|hsa:23539|SLC16A8, MCT3, REMP; solute carrier family 16 (monocarboxylate transporter), member 8; K08185 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 8 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 3 GN=SLC16A8 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: monocarboxylate transporter 3 [Orcinus orca] 
ENSG00000100162(CENPM)	--	23.053179	291	26.46774962	334	27.49724418	352	21.94338857	282	20.3061177	255	23.339597	291	0.965104585	-0.075749939	normal	0.763847155	-0.408652774	normal	0.91023756	-0.281515406	normal	0.347670357	-0.259680169	normal	--	--	--	K11505|8.2832e-117|pps:100990934|CENPM; centromere protein M; K11505 centromere protein M (A)	--	--	--	Centromere protein M (CENP-M)	Centromere protein M GN=CENPM OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein M [Equus przewalskii]
ENSG00000100167(SEPT3)	--	1.96985163	172	1.94937253	173	1.879489323	166	1.691985776	145	2.398638027	196	1.423505407	120	0.932668648	-0.274513247	normal	0.955873995	0.157362092	normal	0.782741287	-0.471367133	normal	0.694852601	-0.170102099	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K16938|0|mcf:102114950|SEPT3; septin 3; K16938 septin 3/9/12 (A)	Bacterial invasion of epithelial cells (ko05100)	[DTZ]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms;; Cytoskeleton"	"Septin;; 50S ribosome-binding GTPase;; Protein of unknown function, DUF258;; AIG1 family;; Elongation factor Tu GTP binding domain"	Neuronal-specific septin-3 GN=SEPT3 OS=Homo sapiens (Human) PE=1 SV=3	DTZ	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms;; Cytoskeleton"	PREDICTED: neuronal-specific septin-3 isoform X1 [Tupaia chinensis]
ENSG00000100170(SLC5A1)	--	0.011764434	1	0.022162906	2	0	0	0.035149994	3	0.022892537	1	0.023381085	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14158|0|hsa:6523|SLC5A1, D22S675, NAGT, SGLT1; solute carrier family 5 (sodium/glucose cotransporter), member 1; K14158 solute carrier family 5 (sodium/glucose cotransporter), member 1 (A)"	Carbohydrate digestion and absorption (ko04973);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium/glucose cotransporter 1 GN=SLC5A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/glucose cotransporter 1 [Ceratotherium simum simum]
ENSG00000100196(KDELR3)	--	10.65181	267	8.813878	231	11.76959	297	10.03216	227	11.77362	293	7.0248	190	0.924816909	-0.263334036	normal	0.887680332	0.319718996	normal	0.142389986	-0.648591059	normal	0.607456448	-0.184267719	normal	--	--	Biological Process: protein retention in ER lumen (GO:0006621);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ER retention sequence binding (GO:0046923);; 	K10949|9.72453e-145|cfr:102513622|KDELR3; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3; K10949 ER lumen protein retaining receptor (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ER lumen protein retaining receptor	ER lumen protein-retaining receptor 3 GN=KDELR3 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ER lumen protein retaining receptor 3 isoform 1 [Ceratotherium simum simum]
ENSG00000100197(CYP2D6)	--	0.630507	14	1.054300015	18	0.562337367	10	0.25121604	7	0.2359212	4	0.35060675	10	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17712|0|hsa:1565|CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1; cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1); K17712 cytochrome P450, family 2, subfamily D, polypeptide 6 [EC:1.14.14.1] (A)"	Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Serotonergic synapse (ko04726)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2D6 GN=CYP2D6 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2D14-like isoform 1 [Equus caballus]
ENSG00000100201(DDX17)	--	77.61541	7515	78.42131439	8015	76.17953	7625	74.686664	7496	79.695129	7776	76.4081666	7812	0.99515862	-0.034477357	normal	0.994853912	-0.06508839	normal	0.995282323	0.026657946	normal	0.935847704	-0.025527779	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K13178|0|hsa:10521|DDX17, P72, RH70; DEAD (Asp-Glu-Ala-Asp) box helicase 17 (EC:3.6.4.13); K13178 ATP-dependent RNA helicase DDX17 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX17 GN=DDX17 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX17 [Mustela putorius furo]
ENSG00000100206(DMC1)	--	1.6335651	54	0.782438233	27	0.894263067	32	1.045366031	27	0.6299946	24	1.03483352	17	0.525026852	-0.990204291	normal	0.984327313	-0.180614839	normal	0.910482554	-0.863972674	normal	0.235536244	-0.75545877	normal	[L]	"Replication, recombination and repair"	Molecular Function: single-stranded DNA binding (GO:0003697);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; 	K10872|0|pps:100977598|DMC1; DNA meiotic recombinase 1; K10872 meiotic recombination protein DMC1 (A)	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Rad51;; recA bacterial DNA recombination protein;; AAA domain;; KaiC;; Helix-hairpin-helix domain	Meiotic recombination protein DMC1/LIM15 homolog GN=DMC1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: meiotic recombination protein DMC1/LIM15 homolog [Dasypus novemcinctus]
ENSG00000100207(TCF20)	--	11.40947644	1511	11.62752535	1521	11.98808105	1645	8.291637	1278	8.581891423	1194	9.525049752	1371	0.934244531	-0.272146752	normal	0.816382266	-0.370227278	normal	0.937596736	-0.27087728	normal	0.064806063	-0.304217161	normal	--	--	--	--	--	--	--	PHD-like zinc-binding domain;; PHD-zinc-finger like domain	Transcription factor 20 GN=TCF20 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor 20 isoform X1 [Galeopterus variegatus]
ENSG00000100209(HSCB)	--	11.78132218	206	7.805161	137	8.47717646	151	7.107909	126	7.671843	136	9.446677766	164	0.107105601	-0.732987409	normal	0.96678734	-0.031645201	normal	0.963537557	0.109800389	normal	0.565217571	-0.234191104	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein oligomerization (GO:0051259);; 	"K04082|3.22652e-167|hsa:150274|HSCB, DNAJC20, HSC20, JAC1, dJ366L4.2; HscB mitochondrial iron-sulfur cluster co-chaperone; K04082 molecular chaperone HscB (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	HSCB C-terminal oligomerisation domain;; DnaJ domain	"Iron-sulfur cluster co-chaperone protein HscB, mitochondrial (Precursor) GN=HSCB OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: iron-sulfur cluster co-chaperone protein HscB, mitochondrial isoform X2 [Ursus maritimus]"
ENSG00000100211(CBY1)	--	8.999434854	195	8.746948235	188	9.270687478	196	15.3651404	330	14.57054029	313	15.00273994	324	0.038387207	0.723730199	normal	0.058994377	0.709535427	normal	0.047272812	0.712529153	normal	0.001713862	0.718738817	normal	--	--	--	--	--	--	--	Chibby family	Protein chibby homolog 1 GN=CBY1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein chibby homolog 1 [Pteropus alecto]
ENSG00000100216(TOMM22)	--	26.3079994	837	28.83030136	928	26.91200137	858	31.229485	1007	30.39610164	961	28.1002257	901	0.943582983	0.235537283	normal	0.978091626	0.028938726	normal	0.976593102	0.062151108	normal	0.648808556	0.107738531	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: intracellular protein transport (GO:0006886);; 	K17769|7.74081e-60|ptr:743431|TOMM22; translocase of outer mitochondrial membrane 22 homolog (yeast); K17769 mitochondrial import receptor subunit TOM22 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Mitochondrial import receptor subunit Tom22	Mitochondrial import receptor subunit TOM22 homolog GN=TOMM22 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import receptor subunit TOM22 homolog [Ovis aries]
ENSG00000100218(RSPH14)	--	7.660652	18	7.285090268	20	1.293872853	12	3.659546	9	2.9579532	4	0.731374637	16	--	--	--	0.446106194	-1.982174496	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	HEAT repeats;; Armadillo/beta-catenin-like repeat;; HEAT repeat;; HEAT-like repeat	Rhabdoid tumor deletion region protein 1 GN=RTDR1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: rhabdoid tumor deletion region protein 1 [Trichechus manatus latirostris]
ENSG00000100219(XBP1)	--	31.4701441	1024	31.79354165	1020	30.59977779	993	30.8562541	1007	31.05938154	991	48.71285545	1559	0.978597665	-0.054901225	normal	0.977657278	-0.062944064	normal	0.023829491	0.641677495	normal	0.643252981	0.208078438	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09027|3.76105e-171|hsa:7494|XBP1, TREB5, XBP-1, XBP2; X-box binding protein 1; K09027 X box-binding protein 1 (A)"	Protein processing in endoplasmic reticulum (ko04141);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; HTLV-I infection (ko05166)	[K]	Transcription	Basic region leucine zipper;; bZIP transcription factor;; bZIP Maf transcription factor	X-box-binding protein 1 GN=XBP1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	X-box-binding protein 1 isoform XBP1(S) [Sus scrofa]
ENSG00000100220(RTCB)	--	36.7508	1416	34.9807	1376	36.4672	1418	36.5597	1420	40.5153	1540	34.4877	1327	0.983228717	-0.026733633	normal	0.976030827	0.140876915	normal	0.979357269	-0.103866072	normal	0.989637954	0.004856781	normal	--	--	Biological Process: RNA processing (GO:0006396);; Molecular Function: RNA ligase activity (GO:0008452);; 	"K14415|0|ptr:458782|RTCB, C22H22orf28; RNA 2',3'-cyclic phosphate and 5'-OH ligase; K14415 tRNA-splicing ligase RtcB [EC:6.5.1.3] (A)"	--	[S]	Function unknown	tRNA-splicing ligase RtcB	tRNA-splicing ligase RtcB homolog {ECO:0000255|HAMAP-Rule:MF_03144} GN=HSPC117 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	tRNA-splicing ligase RtcB-like protein [Camelus ferus]
ENSG00000100221(JOSD1)	--	14.54465862	828	14.56728469	999	14.29531658	949	16.96112329	1091	15.517126	1018	18.49428625	1245	0.802352393	0.366522089	normal	0.979173231	0.005745804	normal	0.770098748	0.382840105	normal	0.167018647	0.252074491	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Biological Process: protein deubiquitination (GO:0016579);; 	K15235|7.54426e-141|ptr:458834|JOSD1; Josephin domain containing 1; K15235 josephin [EC:3.4.19.12] (A)	--	[R]	General function prediction only	Josephin	Josephin-1 GN=JOSD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: josephin-1 [Ceratotherium simum simum]
ENSG00000100225(FBXO7)	--	37.85165018	1332	37.97733883	1345	36.58026	1278	35.29855917	1236	37.19377866	1320	39.56865782	1418	0.974816815	-0.138581601	normal	0.981609902	-0.048439822	normal	0.975195333	0.14151921	normal	0.967377887	-0.013937468	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10293|0|ggo:101146080|FBXO7; F-box only protein 7 isoform 1; K10293 F-box protein 7 (A)	--	--	--	PI31 proteasome regulator N-terminal;; F-box-like;; F-box domain	F-box only protein 7 GN=FBXO7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box only protein 7 isoform X1 [Galeopterus variegatus]
ENSG00000100226(GTPBP1)	--	3.740662	371	3.7548435	376	3.841977	379	5.156961249	484	4.133390053	411	6.108115769	477	0.832773284	0.351478087	normal	0.963347056	0.106569123	normal	0.870658205	0.322351065	normal	0.270806532	0.263790106	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	Elongation factor Tu GTP binding domain;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2	GTP-binding protein 1 GN=GTPBP1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: GTP-binding protein 1 isoform 1 [Ceratotherium simum simum] 
ENSG00000100227(POLDIP3)	--	17.03562002	1161	17.3009394	1200	17.85432828	1207	19.73678791	1341	19.6383135	1322	19.96333927	1355	0.968041322	0.176891055	normal	0.976532771	0.118119353	normal	0.971954655	0.158388341	normal	0.466248834	0.15023265	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Polymerase delta-interacting protein 3 GN=POLDIP3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: polymerase delta-interacting protein 3 isoform 1 [Orcinus orca] 
ENSG00000100228(RAB36)	--	2.929046224	212	2.942927058	198	3.481805371	244	4.294428428	303	3.4828578	256	3.690177935	232	0.609683277	0.481488936	normal	0.871736531	0.34688123	normal	0.964440169	-0.08053582	normal	0.417277436	0.252691422	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07922|0|hsa:9609|RAB36; RAB36, member RAS oncogene family; K07922 Ras-related protein Rab-36 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-36 GN=RAB36 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-36 [Ursus maritimus]
ENSG00000100234(TIMP3)	--	0.0122297	1	0.0242341	2	0	0	0.036674	3	0.035729	2	0.0121236	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase inhibitor activity (GO:0008191);; 	K16866|2.04525e-157|nle:100594545|TIMP3; TIMP metallopeptidase inhibitor 3; K16866 metalloproteinase inhibitor 3 (A)	Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	[R]	General function prediction only	Tissue inhibitor of metalloproteinase	Metalloproteinase inhibitor 3 (Precursor) GN=TIMP3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	metalloproteinase inhibitor 3 precursor [Ovis aries] 
ENSG00000100239(PPP6R2)	--	9.161098873	752	7.6413652	640	8.30001853	712	7.725853008	639	7.814546167	652	7.918282895	669	0.921783334	-0.265160472	normal	0.97388227	0.005360951	normal	0.971039178	-0.097947809	normal	0.622232469	-0.123252497	normal	--	--	--	"K15500|0|hsa:9701|PPP6R2, KIAA0685, PP6R2, SAP190, SAPS2; protein phosphatase 6, regulatory subunit 2; K15500 serine/threonine-protein phosphatase 6 regulatory subunit 2 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	SIT4 phosphatase-associated protein	Serine/threonine-protein phosphatase 6 regulatory subunit 2 GN=PPP6R2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 2 [Tupaia chinensis]
ENSG00000100241(SBF1)	--	16.827441	2389	14.59093001	2199	16.566178	2467	14.06352593	2101	15.534449	2262	16.66472002	2454	0.969763011	-0.21601468	normal	0.98743494	0.019311673	normal	0.988630565	-0.015904134	normal	0.769851986	-0.070073856	normal	--	--	--	"K18061|0|hsa:6305|SBF1, CMT4B3, DENND7A, MTMR5; SET binding factor 1; K18061 myotubularin-related protein 5/13 (A)"	--	[R]	General function prediction only	Myotubularin-like phosphatase domain;; Myotubularin protein;; DENN (AEX-3) domain;; uDENN domain;; dDENN domain;; GRAM domain;; PH domain	Myotubularin-related protein 5 GN=SBF1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: myotubularin-related protein 5 [Oryctolagus cuniculus]
ENSG00000100242(SUN2)	--	31.61460716	1971	28.92405213	1778	30.85863103	1942	32.41753293	2050	33.52280318	2151	33.95723292	2098	0.986750262	0.025844116	normal	0.954699786	0.253129651	normal	0.983960684	0.103102773	normal	0.55007551	0.125429199	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Sad1 / UNC-like C-terminal	SUN domain-containing protein 2 GN=SUN2 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: SUN domain-containing protein 2 isoform X2 [Galeopterus variegatus]
ENSG00000100243(CYB5R3)	--	44.372404	1872	43.74999801	1828	45.430631	1890	48.51983912	1990	43.37365609	1794	51.0818966	2167	0.985653363	0.057310109	normal	0.984931113	-0.048472258	normal	0.973953543	0.188880233	normal	0.777536442	0.069343886	normal	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00326|0|pps:100982559|NADH-cytochrome b5 reductase 3; K00326 cytochrome-b5 reductase [EC:1.6.2.2] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Oxidoreductase FAD-binding domain;; Oxidoreductase NAD-binding domain;; Ferric reductase NAD binding domain	NADH-cytochrome b5 reductase 3 soluble form GN=CYB5R3 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH-cytochrome b5 reductase 3-like [Trichechus manatus latirostris]
ENSG00000100253(MIOX)	--	0	0	0.05576934	1	0	0	0	0	0	0	0.132863633	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: iron ion binding (GO:0005506);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: inositol catabolic process (GO:0019310);; Molecular Function: inositol oxygenase activity (GO:0050113);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00469|0|hsa:55586|MIOX, ALDRL6; myo-inositol oxygenase (EC:1.13.99.1); K00469 inositol oxygenase [EC:1.13.99.1] (A)"	Ascorbate and aldarate metabolism (ko00053);; Inositol phosphate metabolism (ko00562)	[R]	General function prediction only	Family of unknown function (DUF706)	Inositol oxygenase GN=MIOX OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: inositol oxygenase [Felis catus]
ENSG00000100258(LMF2)	--	23.01316	994	22.230429	968	23.2366	1028	27.30102	1171	26.02562	1123	24.60285	1069	0.958190503	0.20529845	normal	0.961030275	0.192572897	normal	0.979310727	0.04806081	normal	0.485777474	0.148231879	normal	--	--	--	--	--	--	--	Lipase maturation factor	Lipase maturation factor 2 GN=LMF2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: lipase maturation factor 2 isoform X1 [Equus caballus]
ENSG00000100263(RHBDD3)	--	10.81767608	286	11.91896003	346	10.303889	299	10.7006	317	9.55611	259	12.3800205	347	0.961481514	0.11703807	normal	0.698507175	-0.437030313	normal	0.944273468	0.20553295	normal	0.94174249	-0.033593858	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Rhomboid family	Rhomboid domain-containing protein 3 GN=RHBDD3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: rhomboid domain-containing protein 3 isoformX1 [Sus scrofa] 
ENSG00000100266(PACSIN2)	--	41.35488077	2384	40.99296514	2417	42.30188296	2501	47.20348663	2798	46.06368468	2584	46.73695969	2512	0.975808684	0.200060357	normal	0.98718279	0.074916701	normal	0.988838039	-0.001958854	normal	0.688522978	0.091005755	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TUZ]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	"Fes/CIP4, and EFC/F-BAR homology domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain"	Protein kinase C and casein kinase substrate in neurons protein 2 GN=PACSIN2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein kinase C and casein kinase substrate in neurons protein 2 [Felis catus]
ENSG00000100271(TTLL1)	--	2.1429563	71	1.793766752	63	1.345442069	45	1.668583324	57	1.261220901	48	2.632369756	91	0.954316298	-0.339471861	normal	0.946899148	-0.402635572	normal	0.126936598	0.983944211	normal	0.897428886	0.110469307	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16599|0|ptr:458886|TTLL1; tubulin tyrosine ligase-like family, member 1; K16599 tubulin polyglutamylase TTLL1 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Probable tubulin polyglutamylase TTLL1 GN=TTLL1 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable tubulin polyglutamylase TTLL1 isoform X2 [Canis lupus familiaris] 
ENSG00000100276(RASL10A)	--	0.273746608	5	0.155188	3	0.149415789	2	0.158290789	3	0.0522198	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K07850|2.97582e-130|ptr:748312|RASL10A; RAS-like, family 10, member A; K07850 Ras-like protein family member 10A (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein	Ras-like protein family member 10A (Precursor) GN=RASL10A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	ras-like protein family member 10A [Bos taurus] 
ENSG00000100280(AP1B1)	--	16.07468164	1474	16.09324866	1447	17.27186026	1590	18.939679	1729	18.35513957	1680	17.76311999	1626	0.967464125	0.19917724	normal	0.968212161	0.19378166	normal	0.984619989	0.023986489	normal	0.507054883	0.137331037	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K12392|0|hsa:162|AP1B1, ADTB1, AP105A, BAM22, CLAPB2; adaptor-related protein complex 1, beta 1 subunit; K12392 AP-1 complex subunit beta-1 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Adaptin N terminal region;; non-SMC mitotic condensation complex subunit 1;; Beta2-adaptin appendage, C-terminal sub-domain;; HEAT repeats;; HEAT repeat;; Adaptin C-terminal domain;; Nuclear condensing complex subunits, C-term domain;; Armadillo/beta-catenin-like repeat;; HEAT-like repeat"	AP-1 complex subunit beta-1 GN=AP1B1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-1 complex subunit beta-1 isoform X1 [Panthera tigris altaica] 
ENSG00000100281(HMGXB4)	--	7.735036014	620	7.057992	562	6.611099214	495	6.186956	501	7.277574073	586	6.069409613	495	0.847698332	-0.337357766	normal	0.971887848	0.038801725	normal	0.971711785	-0.008266188	normal	0.708094642	-0.105554904	normal	--	--	--	"K11298|0|hsa:10042|HMGXB4, HMG2L1, HMGBCG, THC211630; HMG box domain containing 4; K11298 high mobility group protein 2-like 1 (A)"	--	--	--	Domain of unknown function (DUF4171);; HMG (high mobility group) box;; HMG-box domain	HMG domain-containing protein 4 GN=HMGXB4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: HMG domain-containing protein 4 isoform X1 [Tupaia chinensis]
ENSG00000100284(TOM1)	--	8.7029739	421	9.5457503	484	6.982853883	358	10.44593636	512	13.01669208	646	13.98141178	706	0.926238635	0.250660777	normal	0.746814369	0.394031593	normal	1.42E-05	0.96844898	normal	0.030247112	0.540912938	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: intracellular protein transport (GO:0006886);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	VHS domain;; GAT domain	Target of Myb protein 1 GN=TOM1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: target of Myb protein 1 isoform X4 [Equus caballus]
ENSG00000100285(NEFH)	--	0	0	0	0	0.040167	4	0.0165479	2	0.00800776	0	0.00820751	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K04574|0|hsa:4744|NEFH, NFH; neurofilament, heavy polypeptide; K04574 neurofilament heavy polypeptide (A)"	Amyotrophic lateral sclerosis (ALS) (ko05014)	--	--	Intermediate filament protein;; Repeat of unknown function (DUF1388)	Neurofilament heavy polypeptide GN=NEFH OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	neurofilament heavy polypeptide [Canis lupus familiaris] 
ENSG00000100288(CHKB)	--	8.794802934	651	10.18936171	665	9.049333264	585	7.290122112	482	8.138431523	550	10.76913449	781	0.517873185	-0.463180803	normal	0.898309265	-0.294611317	normal	0.697299567	0.407679332	normal	0.849930177	-0.088331055	normal	--	--	--	"K14156|0|hsa:1120|CHKB, CHETK, CHKL, CK, CKB, CKEKB, EK, EKB, MDCMC; choline kinase beta (EC:2.7.1.32 2.7.1.82); K14156 choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82] (A)"	Glycerophospholipid metabolism (ko00564);; Choline metabolism in cancer (ko05231)	[M]	Cell wall/membrane/envelope biogenesis	Choline/ethanolamine kinase;; Phosphotransferase enzyme family;; Ecdysteroid kinase	Choline/ethanolamine kinase GN=CHKB OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: choline/ethanolamine kinase [Camelus bactrianus]
ENSG00000100290(BIK)	--	1.13613	14	0.637237	8	0.548528	6	1.53308	19	1.58083	19	2.01387	25	--	--	--	--	--	--	0.349737155	1.812116642	normal	--	--	--	--	--	Biological Process: apoptotic process (GO:0006915);; 	"K18452|1.86276e-93|hsa:638|BIK, BIP1, BP4, NBK; BCL2-interacting killer (apoptosis-inducing); K18452 Bcl-2-interacting killer (A)"	--	--	--	"Bcl2-interacting killer, BH3-domain containing"	Bcl-2-interacting killer GN=BIK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: bcl-2-interacting killer [Galeopterus variegatus]
ENSG00000100292(HMOX1)	--	277.4436848	8438	456.0349326	14053	312.3295848	9735	96.20333844	2896	128.33708	3866	239.2573667	7391	0	-1.573158223	down	0	-1.882976826	down	0.877926847	-0.405630291	normal	0.022049049	-1.205889248	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: heme oxygenase (decyclizing) activity (GO:0004392);; Biological Process: heme oxidation (GO:0006788);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00510|0|ptr:470195|HMOX1; heme oxygenase (decycling) 1; K00510 heme oxygenase [EC:1.14.99.3] (A)	Porphyrin and chlorophyll metabolism (ko00860);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Heme oxygenase	Heme oxygenase 1 GN=HMOX1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	heme oxygenase 1 [Canis lupus familiaris]
ENSG00000100294(MCAT)	--	13.1494186	362	11.3613335	313	12.10125162	354	13.43535119	413	15.17257539	448	13.1822595	394	0.956204327	0.158688953	normal	0.485183231	0.493905164	normal	0.958540196	0.145565136	normal	0.286566985	0.265290054	normal	[I]	Lipid transport and metabolism	--	K00645|0|pps:100990465|MCAT; malonyl CoA:ACP acyltransferase (mitochondrial); K00645 [acyl-carrier-protein] S-malonyltransferase [EC:2.3.1.39] (A)	Fatty acid biosynthesis (ko00061);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	Acyl transferase domain	"Malonyl-CoA-acyl carrier protein transacylase, mitochondrial (Precursor) GN=MCAT OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: malonyl-CoA-acyl carrier protein transacylase, mitochondrial isoform X1 [Physeter catodon]"
ENSG00000100296(THOC5)	--	72.45031916	3349	58.90584772	2848	68.55372528	3185	53.86430527	2483	57.39273728	2675	51.26625473	2396	0.562700399	-0.462231051	normal	0.986366789	-0.111775557	normal	0.732877044	-0.418726874	normal	0.035341757	-0.333815185	normal	--	--	--	"K13174|0|hsa:8563|THOC5, C22orf19, Fmip, PK1.3, fSAP79; THO complex 5; K13174 THO complex subunit 5 (A)"	RNA transport (ko03013)	[S]	Function unknown	Fms-interacting protein	THO complex subunit 5 homolog GN=THOC5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: THO complex subunit 5 homolog isoform X6 [Equus caballus] 
ENSG00000100297(MCM5)	--	46.01350644	2190	47.53900359	2436	50.66011564	2558	38.37396424	1822	42.15317434	2029	26.30378432	1345	0.929696609	-0.2960121	normal	0.942402436	-0.284977666	normal	3.12E-06	-0.934925873	normal	0.012711783	-0.489122609	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; 	"K02209|0|hsa:4174|MCM5, CDC46, P1-CDC46; minichromosome maintenance complex component 5 (EC:3.6.4.12); K02209 DNA replication licensing factor MCM5 [EC:3.6.4.12] (A)"	DNA replication (ko03030);; Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; MCM N-terminal domain;; Magnesium chelatase, subunit ChlI"	DNA replication licensing factor MCM5 GN=MCM5 OS=Homo sapiens (Human) PE=1 SV=5	L	"Replication, recombination and repair"	PREDICTED: DNA replication licensing factor MCM5 [Felis catus] 
ENSG00000100298(APOBEC3H)	--	0.354133332	3	0.318588419	2	0	0	0.488497449	3	0	0	0.1321498	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	"K18750|8.62298e-127|pps:100983664|APOBEC3H; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H; K18750 C->U-editing enzyme APOBEC3 [EC:3.5.4.-] (A)"	--	--	--	APOBEC-like N-terminal domain;; APOBEC-like C-terminal domain;; Cytidine and deoxycytidylate deaminase zinc-binding region	DNA dC-	A	RNA processing and modification	"PREDICTED: apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3Z3 isoform X1 [Equus caballus] "
ENSG00000100299(ARSA)	--	19.15401678	693	17.51044356	647	17.23943909	654	14.55414795	517	15.59598831	561	13.73031589	508	0.55191064	-0.452357467	normal	0.940103163	-0.226622072	normal	0.789284603	-0.371775457	normal	0.068505371	-0.35149212	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K01134|0|hsa:410|ARSA, MLD; arylsulfatase A (EC:3.1.6.8); K01134 arylsulfatase A [EC:3.1.6.8] (A)"	Sphingolipid metabolism (ko00600);; Lysosome (ko04142)	[R]	General function prediction only	Sulfatase;; C-terminal region of aryl-sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	Arylsulfatase A component C (Precursor) GN=ARSA OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: arylsulfatase A isoform X1 [Ursus maritimus] 
ENSG00000100300(TSPO)	--	124.819981	1242	128.513535	1339	136.17123	1385	160.8398939	1652	159.737454	1588	142.03841	1424	0.78902577	0.380307152	normal	0.95843449	0.224395446	normal	0.983069831	0.031737551	normal	0.241491081	0.212378905	normal	[T]	Signal transduction mechanisms	Cellular Component: integral component of membrane (GO:0016021);; 	"K05770|9.13926e-104|hsa:706|TSPO, BPBS, BZRP, DBI, IBP, MBR, PBR, PBS, PKBS, PTBR, mDRC, pk18; translocator protein (18kDa); K05770 benzodiazapine receptor (A)"	Neuroactive ligand-receptor interaction (ko04080);; HTLV-I infection (ko05166)	[T]	Signal transduction mechanisms	TspO/MBR family	Translocator protein GN=TSPO OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: translocator protein [Elephantulus edwardii]
ENSG00000100302(RASD2)	--	4.0712399	158	2.0750439	104	2.975146	129	3.295898	152	4.305358	180	1.539528	72	0.965339472	-0.085834405	normal	0.120986549	0.761472435	normal	0.138871019	-0.836286432	normal	0.985016047	0.024496917	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07844|0|pps:100978711|RASD2; RASD family, member 2; K07844 RASD family, member 2 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	GTP-binding protein Rhes (Precursor) GN=RASD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GTP-binding protein Rhes [Ailuropoda melanoleuca] 
ENSG00000100304(TTLL12)	--	9.21890782	664	10.75469649	785	9.440398	673	16.16044748	1159	15.15680469	1086	13.434633	955	0.001154038	0.771425956	normal	0.576522472	0.446099429	normal	0.361177108	0.495663184	normal	0.000224818	0.570725535	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16609|0|hsa:23170|TTLL12, dJ526I14.2; tubulin tyrosine ligase-like family, member 12; K16609 tubulin--tyrosine ligase-like protein 12 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin--tyrosine ligase-like protein 12 GN=TTLL12 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin--tyrosine ligase-like protein 12 [Galeopterus variegatus]
ENSG00000100307(CBX7)	--	3.272332565	222	2.634673719	208	3.02669664	238	2.202072056	167	1.35990826	102	2.136877314	162	0.771945241	-0.438035163	normal	0.001009154	-1.038425525	down	0.46005147	-0.558927537	normal	0.018621943	-0.653469631	normal	--	--	--	K11454|1.92896e-155|mcf:102125817|CBX7; chromobox homolog 7; K11454 chromobox protein 7 (A)	--	[B]	Chromatin structure and dynamics	Chromo (CHRromatin Organisation MOdifier) domain	Chromobox protein homolog 7 GN=CBX7 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: chromobox protein homolog 7 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000100311(PDGFB)	--	3.324151852	157	2.184494839	141	2.149926984	140	8.20011631	455	6.781669125	403	2.844215314	184	2.12E-11	1.495284323	up	1.71E-10	1.483824376	up	0.868917182	0.382374075	normal	0.056026353	1.226814474	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	"K17386|2.07731e-167|hsa:5155|PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis; platelet-derived growth factor beta polypeptide; K17386 platelet-derived growth factor subunit B (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Choline metabolism in cancer (ko05231)	--	--	"PDGF/VEGF domain;; Platelet-derived growth factor, N terminal region"	Platelet-derived growth factor subunit B (Precursor) GN=PDGFB OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: platelet-derived growth factor subunit B isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000100314(CABP7)	--	0.118034	8	0	0	0.154542	10	0.0442764	3	0.0576147	3	0.0437891	3	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand	Calcium-binding protein 7 GN=CABP7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: calcium-binding protein 7 [Chrysochloris asiatica]
ENSG00000100316(RPL3)	--	883.8596396	24216	769.0531251	21637	795.4132861	22212	900.0172039	24730	890.9887193	24247	792.4567954	21780	0.998251287	-0.000530571	normal	0.997011361	0.142869783	normal	0.998000643	-0.036624271	normal	0.914944104	0.034381392	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02925|0|pps:100985457|RPL3; ribosomal protein L3; K02925 large subunit ribosomal protein L3e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L3	60S ribosomal protein L3 GN=RPL3 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L3 [Ceratotherium simum simum] 
ENSG00000100319(ZMAT5)	--	16.617218	268	12.65318	200	14.87086	239	13.283514	213	14.516836	226	14.765166	226	0.85481904	-0.359891545	normal	0.955529758	0.153801702	normal	0.963863507	-0.088403955	normal	0.786760395	-0.109248132	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K13152|3.48161e-123|pps:100967402|ZMAT5; zinc finger, matrin-type 5; K13152 U11/U12 small nuclear ribonucleoprotein 20 kDa protein (A)"	--	[A]	RNA processing and modification	Zinc finger C-x8-C-x5-C-x3-H type (and similar);; U1 zinc finger	Zinc finger matrin-type protein 5 GN=ZMAT5 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: zinc finger matrin-type protein 5 isoform X1 [Tupaia chinensis] 
ENSG00000100320(RBFOX2)	--	22.34401037	2167	21.29849001	2094	22.15003983	2250	28.46438046	2736	25.77098634	2512	26.26544599	2418	0.930079314	0.305343788	normal	0.963136967	0.24098938	normal	0.985911438	0.095535848	normal	0.228643067	0.214122931	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K14946|0|ocu:100350990|RBFOX2; RNA binding protein, fox-1 homolog (C. elegans) 2; K14946 RNA binding protein fox-1 (A)"	--	[R]	General function prediction only	"Calcitonin gene-related peptide regulator C terminal;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA binding protein fox-1 homolog 2 GN=RBFOX2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: RNA binding protein fox-1 homolog 2 [Oryctolagus cuniculus]
ENSG00000100321(SYNGR1)	--	10.97705268	420	13.78738715	382	8.857599192	385	10.29223399	266	10.10815886	327	9.863318067	282	0.039513262	-0.686609408	normal	0.928560134	-0.244660463	normal	0.627205276	-0.455356122	normal	0.038969293	-0.460943758	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Membrane-associating domain	Synaptogyrin-1 GN=SYNGR1 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptogyrin-1 [Camelus dromedarius]
ENSG00000100324(TAB1)	--	7.320522759	554	8.008759	570	7.95533	598	7.137127	525	8.259103	590	7.242702	546	0.966951893	-0.108092806	normal	0.972315348	0.028252801	normal	0.963539421	-0.139167514	normal	0.809572548	-0.07294637	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; 	K04403|0|pps:100985128|TAB1; TGF-beta activated kinase 1/MAP3K7 binding protein 1; K04403 TAK1-binding protein 1 (A)	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein phosphatase 2C	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 GN=TAB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 [Eptesicus fuscus]
ENSG00000100325(ASCC2)	--	12.65115216	786	12.030416	751	12.01135231	744	15.92484011	968	19.346492	990	13.323406	819	0.923675891	0.269170672	normal	0.785777225	0.376526823	normal	0.9689443	0.130017416	normal	0.162785749	0.262188142	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K18667|0|ptr:458747|ASCC2; activating signal cointegrator 1 complex subunit 2; K18667 activating signal cointegrator complex subunit 2 (A)	--	[K]	Transcription	CUE domain	Activating signal cointegrator 1 complex subunit 2 GN=ASCC2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: activating signal cointegrator 1 complex subunit 2 isoformX1 [Equus caballus]
ENSG00000100330(MTMR3)	--	6.10575541	828	5.905821832	790	5.817644003	781	6.175762727	835	6.453507879	853	5.896201585	745	0.977259217	-0.018652368	normal	0.973400294	0.089102361	normal	0.974025719	-0.076222431	normal	1	-0.001234547	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K18082|0|hsa:8897|MTMR3, FYVE-DSP1, ZFYVE10; myotubularin related protein 3 (EC:3.1.3.48 3.1.3.64 3.1.3.95); K18082 myotubularin-related protein 3/4 [EC:3.1.3.48] (A)"	--	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	Myotubularin-like phosphatase domain;; FYVE zinc finger;; Protein-tyrosine phosphatase	Myotubularin-related protein 3 GN=MTMR3 OS=Homo sapiens (Human) PE=1 SV=3	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: myotubularin-related protein 3 isoform X2 [Galeopterus variegatus]
ENSG00000100335(MIEF1)	--	10.8735344	1043	10.23457283	987	11.72846136	1083	12.72264	1225	14.28308033	1333	11.984774	1190	0.960377083	0.200936988	normal	0.70236619	0.411583756	normal	0.974519657	0.127467031	normal	0.16915137	0.246723811	normal	--	--	--	--	--	--	--	Mab-21 protein	Mitochondrial dynamics protein MID51 GN=MIEF1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitochondrial dynamic protein MID51 isoform X3 [Canis lupus familiaris] 
ENSG00000100342(APOL1)	--	3.354344507	193	3.642247338	235	2.655694063	151	13.1966865	687	12.0415227	627	13.51961861	668	0	1.792816271	up	6.47E-11	1.388693524	up	0	2.125944075	up	2.15E-23	1.753381507	up	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K14480|0|hsa:8542|APOL1, APO-L, APOL, APOL-I, FSGS4; apolipoprotein L, 1; K14480 apolipoprotein L (A)"	African trypanosomiasis (ko05143)	--	--	Apolipoprotein L	Apolipoprotein L1 (Precursor) GN=APOL1 OS=Homo sapiens (Human) PE=1 SV=5	P	Inorganic ion transport and metabolism	PREDICTED: apolipoprotein L2-like [Galeopterus variegatus]
ENSG00000100344(PNPLA3)	--	2.6358378	265	2.885786003	273	2.6505771	289	1.287069727	127	1.289855859	133	2.09622165	212	8.74E-05	-1.082714271	down	0.000176206	-1.050379845	down	0.692401184	-0.452520582	normal	0.000619151	-0.828626803	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K13534|0|hsa:80339|PNPLA3, ADPN, C22orf20, iPLA(2)epsilon; patatin-like phospholipase domain containing 3 (EC:3.1.1.3); K13534 patatin-like phospholipase domain-containing protein 3 [EC:3.1.1.3 2.3.1.-] (A)"	Glycerolipid metabolism (ko00561)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Patatin-like phospholipase	Patatin-like phospholipase domain-containing protein 3 GN=PNPLA3 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: patatin-like phospholipase domain-containing protein 3 isoform X2 [Ailuropoda melanoleuca]
ENSG00000100345(MYH9)	--	153.1566229	30525	151.8488711	30834	165.5335877	33937	218.7425772	43495	182.2087352	36084	152.5562515	30404	0.852650867	0.480005673	normal	0.996573602	0.205401338	normal	0.997440252	-0.166881479	normal	0.478336423	0.184686657	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10352|0|hsa:4627|MYH9, BDPLT6, DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHC-IIA, NMMHCA; myosin, heavy chain 9, non-muscle; K10352 myosin heavy chain (A)"	Tight junction (ko04530);; Regulation of actin cytoskeleton (ko04810);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; Myosin N-terminal SH3-like domain;; IQ calmodulin-binding motif	Myosin-9 GN=MYH9 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: myosin-9 [Galeopterus variegatus]
ENSG00000100346(CACNA1I)	--	0.256301552	51	0.161584578	32	0.245636754	49	0.368230669	73	0.909606401	186	0.384248481	76	0.92144727	0.474563536	normal	1.22E-15	2.463366337	up	0.835013035	0.609704205	normal	0.20081067	1.323413261	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04856|0|hsa:8911|CACNA1I, Cav3.3, ca(v)3.3; calcium channel, voltage-dependent, T type, alpha 1I subunit; K04856 voltage-dependent calcium channel T type alpha-1I (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; Circadian entrainment (ko04713)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Polycystin cation channel	Voltage-dependent T-type calcium channel subunit alpha-1I GN=CACNA1I OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent T-type calcium channel subunit alpha-1I [Trichechus manatus latirostris]
ENSG00000100347(SAMM50)	--	26.3302	763	25.0747	729	28.3337	819	26.9398	787	29.7966	862	23.5483	684	0.976494604	0.013820913	normal	0.947286426	0.219922549	normal	0.921883557	-0.267617068	normal	0.985893701	-0.00766043	normal	[M]	Cell wall/membrane/envelope biogenesis	Cellular Component: outer membrane (GO:0019867);; 	"K07277|0|hsa:25813|SAMM50, OMP85, SAM50, TOB55, TRG-3, YNL026W; SAMM50 sorting and assembly machinery component; K07277 outer membrane protein insertion porin family (A)"	--	[R]	General function prediction only	Surface antigen	Sorting and assembly machinery component 50 homolog GN=SAMM50 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting and assembly machinery component 50 homolog [Felis catus]
ENSG00000100348(TXN2)	--	28.406402	744	33.17754	845	32.68665	821	35.73651	871	34.17565	823	36.91237	933	0.955586582	0.196163156	normal	0.975505804	-0.059377785	normal	0.962414491	0.175899291	normal	0.675455817	0.103402562	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like	"Thioredoxin, mitochondrial (Precursor) GN=TXN2 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: thioredoxin, mitochondrial [Galeopterus variegatus] "
ENSG00000100350(FOXRED2)	--	18.4735059	1522	20.15158315	1838	18.33810949	1692	12.98306421	1118	13.71424868	1198	19.4356247	1586	0.437236082	-0.475318066	normal	0.029594721	-0.63827962	normal	0.981696291	-0.101534487	normal	0.080642587	-0.392811939	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain;; Pyridine nucleotide-disulphide oxidoreductase	FAD-dependent oxidoreductase domain-containing protein 2 (Precursor) GN=FOXRED2 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: FAD-dependent oxidoreductase domain-containing protein 2 isoform X2 [Galeopterus variegatus]
ENSG00000100353(EIF3D)	--	66.26408586	2903	64.03653587	2809	64.71864419	2783	66.16368201	2852	61.00932824	2598	63.44423859	2718	0.989261839	-0.056372751	normal	0.984609868	-0.134006708	normal	0.989191441	-0.0423636	normal	0.740446355	-0.078039395	normal	--	--	Molecular Function: translation initiation factor activity (GO:0003743);; Cellular Component: cytoplasm (GO:0005737);; Cellular Component: eukaryotic translation initiation factor 3 complex (GO:0005852);; 	"K03251|0|ptr:458797|EIF3D, EIF3S7; eukaryotic translation initiation factor 3, subunit D; K03251 translation initiation factor 3 subunit D (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Eukaryotic translation initiation factor 3 subunit 7 (eIF-3)	Eukaryotic translation initiation factor 3 subunit D {ECO:0000255|HAMAP-Rule:MF_03003} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	eukaryotic translation initiation factor 3 subunit D [Bos taurus] 
ENSG00000100354(TNRC6B)	--	7.141583964	983	4.833033827	1217	3.692045905	1021	5.217316874	1065	5.188332918	874	5.161876436	1052	0.977029608	0.084630747	normal	0.36182384	-0.498316223	normal	0.979585036	0.034809601	normal	0.579285972	-0.12837468	normal	--	--	--	K18412|0|mcf:102143861|TNRC6B; trinucleotide repeat containing 6B; K18412 trinucleotide repeat-containing gene 6 protein (A)	--	--	--	"Argonaute hook;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Trinucleotide repeat-containing gene 6B protein GN=TNRC6B OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: trinucleotide repeat-containing gene 6B protein isoform X4 [Equus caballus]
ENSG00000100359(SGSM3)	--	12.035394	537	9.980285	439	9.79006	457	6.854252354	308	7.451239	334	7.437479	364	0.001136878	-0.829646392	normal	0.722503933	-0.414158147	normal	0.856410393	-0.335301105	normal	0.008194803	-0.531158745	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	Rab-GTPase-TBC domain;; RUN domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Small G protein signaling modulator 3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: small G protein signaling modulator 3 isoform X3 [Felis catus]
ENSG00000100360(IFT27)	--	19.83914776	336	21.62596454	374	19.88367765	347	14.17345216	244	15.95013006	268	19.81854097	339	0.550504613	-0.489771676	normal	0.50168894	-0.499832364	normal	0.967893789	-0.041757703	normal	0.184610996	-0.333010448	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07934|9.36939e-136|ptr:458800|IFT27, RABL4; intraflagellar transport 27; K07934 intraflagellar transport protein 27 homolog (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein	Intraflagellar transport protein 27 homolog GN=IFT27 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: intraflagellar transport protein 27 homolog isoform X3 [Ursus maritimus]
ENSG00000100364(KIAA0930)	--	41.98056375	2408	41.89904255	2509	43.10958998	2490	49.66323245	2876	46.6346531	2807	41.53824576	2423	0.970505951	0.225264373	normal	0.983871422	0.140409993	normal	0.988150901	-0.047613464	normal	0.616786078	0.108447176	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2045)	Uncharacterized protein KIAA0930 GN=KIAA0930 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	TPA: hypothetical protein BOS_6223 [Bos taurus]
ENSG00000100368(CSF2RB)	--	0	0	0	0	0	0	0.015950382	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04738|0|hsa:1439|CSF2RB, CD131, CDw131, IL3RB, IL5RB, SMDP5; colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage); K04738 cytokine receptor common subunit beta (A)"	Cytokine-cytokine receptor interaction (ko04060);; Apoptosis (ko04210);; Jak-STAT signaling pathway (ko04630)	--	--	"Fibronectin type III domain;; Interleukin-6 receptor alpha chain, binding;; Interferon-alpha/beta receptor, fibronectin type III;; Tissue factor"	Cytokine receptor common subunit beta (Precursor) GN=CSF2RB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cytokine receptor common subunit beta [Galeopterus variegatus]
ENSG00000100372(SLC25A17)	--	13.641387	456	14.13046677	468	13.95867164	460	11.64064576	388	12.47438531	414	9.961171588	330	0.919147542	-0.262848025	normal	0.946921316	-0.197624833	normal	0.494177123	-0.485565659	normal	0.17219571	-0.311564947	normal	--	--	--	"K13354|0|pps:100979010|SLC25A17; solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17; K13354 solute carrier family 25 (peroxisomal adenine nucleotide transporter), member 17 (A)"	Peroxisome (ko04146)	[C]	Energy production and conversion	Mitochondrial carrier protein	Peroxisomal membrane protein PMP34 GN=SLC25A17 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: peroxisomal membrane protein PMP34 isoform 1 [Ceratotherium simum simum]
ENSG00000100373(UPK3A)	--	0	0	0.06668	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uroplakin-3a (Precursor) GN=UPK3A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: uroplakin-3a isoform X1 [Camelus ferus] 
ENSG00000100376(FAM118A)	--	5.777975908	315	5.439804402	286	6.305661729	311	6.031892359	288	5.169615464	268	4.386418832	251	0.955148444	-0.159302276	normal	0.960517793	-0.114582659	normal	0.888826072	-0.315805874	normal	0.520746173	-0.197990997	normal	--	--	--	--	--	--	--	SIR2-like domain	Protein FAM118A GN=FAM118A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM118A isoform X2 [Bison bison bison] 
ENSG00000100379(KCTD17)	--	15.630871	665	14.134951	628	15.03073709	675	13.348689	556	14.660876	594	11.8384403	539	0.902579893	-0.288371878	normal	0.968511397	-0.101476878	normal	0.855718167	-0.332059298	normal	0.254312962	-0.241707028	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD17 GN=KCTD17 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD17 isoform X3 [Camelus bactrianus]
ENSG00000100380(ST13)	--	73.57733	4120	82.6951	4260	82.267266	4253	76.16027565	4148	73.01240398	3971	78.769258	4174	0.992302736	-0.021052882	normal	0.989321663	-0.122732488	normal	0.99226565	-0.035329016	normal	0.813067828	-0.060528708	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K09560|0|ggo:101150126|hsc70-interacting protein-like; K09560 suppressor of tumorigenicity protein 13 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Hsc70-interacting protein GN=ST13 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: hsc70-interacting protein isoform 1 [Sus scrofa]
ENSG00000100385(IL2RB)	--	0	0	0	0	0	0	0.013058388	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05069|0|hsa:3560|IL2RB, CD122, IL15RB, P70-75; interleukin 2 receptor, beta; K05069 interleukin 2 receptor beta (A)"	Cytokine-cytokine receptor interaction (ko04060);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Measles (ko05162);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202)	--	--	--	Interleukin-2 receptor subunit beta (Precursor) GN=IL2RB OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: interleukin-2 receptor subunit beta [Galeopterus variegatus]
ENSG00000100387(RBX1)	--	24.0468	417	23.5098	409	25.2357	436	29.1347	513	24.6594	425	21.8125	378	0.916580065	0.267190353	normal	0.968764223	0.033812793	normal	0.942089927	-0.213437531	normal	0.914498188	0.038400931	normal	[OD]	"Posttranslational modification, protein turnover, chaperones;; Cell cycle control, cell division, chromosome partitioning"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: zinc ion binding (GO:0008270);; 	K03868|6.18575e-76|aml:100469702|uncharacterized LOC100469702; K03868 RING-box protein 1 (A)	Nucleotide excision repair (ko03420);; HIF-1 signaling pathway (ko04066);; Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Wnt signaling pathway (ko04310);; TGF-beta signaling pathway (ko04350);; Circadian rhythm (ko04710);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[O]	"Posttranslational modification, protein turnover, chaperones"	RING-H2 zinc finger;; Anaphase-promoting complex subunit 11 RING-H2 finger;; Ring finger domain	"E3 ubiquitin-protein ligase RBX1, N-terminally processed GN=RBX1 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RBX1 [Pteropus alecto]
ENSG00000100393(EP300)	--	11.62074	2325	12.164094	2486	10.85299253	2169	9.47455	1927	11.69590494	2336	11.88435376	2390	0.927597451	-0.301487174	normal	0.985028692	-0.111142817	normal	0.983158361	0.131601682	normal	0.691016823	-0.089925388	normal	[BK]	Chromatin structure and dynamics;; Transcription	"Cellular Component: histone acetyltransferase complex (GO:0000123);; Molecular Function: transcription cofactor activity (GO:0003712);; Molecular Function: transcription coactivator activity (GO:0003713);; Molecular Function: histone acetyltransferase activity (GO:0004402);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: histone acetylation (GO:0016573);; "	"K04498|0|hsa:2033|EP300, KAT3B, RSTS2, p300; E1A binding protein p300 (EC:2.3.1.48); K04498 E1A/CREB-binding protein [EC:2.3.1.48] (A)"	cAMP signaling pathway (ko04024);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; TGF-beta signaling pathway (ko04350);; Adherens junction (ko04520);; Jak-STAT signaling pathway (ko04630);; Long-term potentiation (ko04720);; Melanogenesis (ko04916);; Thyroid hormone signaling pathway (ko04919);; Huntington's disease (ko05016);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Prostate cancer (ko05215)	[K]	Transcription	"Histone acetylation protein;; Creb binding;; KIX domain;; TAZ zinc finger;; Domain of Unknown Function (DUF902);; Bromodomain;; Zinc finger, ZZ type"	Histone acetyltransferase p300 GN=EP300 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: histone acetyltransferase p300 [Galeopterus variegatus]
ENSG00000100395(L3MBTL2)	--	7.204646004	515	6.57047454	476	8.840385008	636	7.037232445	501	7.040093175	486	6.923699306	495	0.969644402	-0.070381191	normal	0.970618124	0.008541327	normal	0.795579845	-0.368892707	normal	0.544924495	-0.155423775	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	mbt repeat	Lethal(3)malignant brain tumor-like protein 2 GN=L3MBTL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: lethal(3)malignant brain tumor-like protein 2 [Balaenoptera acutorostrata scammoni]
ENSG00000100399(CHADL)	--	0.031337606	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat	Chondroadherin-like protein (Precursor) GN=CHADL OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: chondroadherin-like protein [Oryctolagus cuniculus]
ENSG00000100401(RANGAP1)	--	41.2722261	2677	38.16571938	2545	43.80789996	2920	60.99439615	3980	52.88420078	3410	47.7466575	3074	0.217688619	0.541062859	normal	0.804997812	0.400473287	normal	0.98932185	0.065824125	normal	0.035889847	0.340198141	normal	[TA]	Signal transduction mechanisms;; RNA processing and modification	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K14319|0|hsa:5905|RANGAP1, Fug1, RANGAP, SD; Ran GTPase activating protein 1; K14319 Ran GTPase-activating protein 1 (A)"	RNA transport (ko03013)	[AYT]	RNA processing and modification;; Nuclear structure;; Signal transduction mechanisms	RanGAP1 C-terminal domain;; Leucine Rich repeat;; Leucine Rich Repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeat	Ran GTPase-activating protein 1 GN=RANGAP1 OS=Homo sapiens (Human) PE=1 SV=1	ATY	RNA processing and modification;; Signal transduction mechanisms;; Nuclear structure	PREDICTED: ran GTPase-activating protein 1 isoform X1 [Felis catus]
ENSG00000100403(ZC3H7B)	--	14.328029	1857	15.908727	2100	16.80533469	2222	16.900613	2182	15.65906461	2011	18.308606	2378	0.971168923	0.201690956	normal	0.984896343	-0.083841098	normal	0.986074794	0.089539539	normal	0.782633671	0.067954104	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	TPR repeat;; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Tetratricopeptide repeat	Zinc finger CCCH domain-containing protein 7B GN=ZC3H7B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger CCCH domain-containing protein 7B isoform X3 [Galeopterus variegatus]
ENSG00000100410(PHF5A)	--	29.1015	511	27.0735	476	29.4714	516	33.0664	588	29.882	519	30.5569	538	0.956654466	0.171180522	normal	0.965961439	0.103032859	normal	0.971185626	0.051794993	normal	0.699047465	0.108834452	normal	--	--	--	K12834|1.2293e-74|mze:101465769|PHD finger-like domain-containing protein 5A-like; K12834 PHD finger-like domain-containing protein 5A (A)	Spliceosome (ko03040)	[S]	Function unknown	PHF5-like protein	PHD finger-like domain-containing protein 5A GN=PHF5A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: PHD finger-like domain-containing protein 5A-like [Elephantulus edwardii]
ENSG00000100412(ACO2)	--	21.2821	1295	19.04816662	1162	20.81320119	1277	17.09671509	1036	17.070688	1032	19.7249874	1204	0.836852552	-0.352291903	normal	0.962006212	-0.192327863	normal	0.978917189	-0.093101008	normal	0.255595881	-0.211211148	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; 	"K01681|0|hsa:50|ACO2, ACONM, ICRD; aconitase 2, mitochondrial (EC:4.2.1.3); K01681 aconitate hydratase [EC:4.2.1.3] (A)"	Citrate cycle (TCA cycle) (ko00020);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[CE]	Energy production and conversion;; Amino acid transport and metabolism	Aconitase family (aconitate hydratase);; Aconitase C-terminal domain	"Aconitate hydratase, mitochondrial (Precursor) GN=ACO2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: aconitate hydratase, mitochondrial [Tupaia chinensis]"
ENSG00000100413(POLR3H)	--	20.25694399	1110	17.38263645	1061	21.61056451	1137	19.28133856	1092	19.92130978	1299	18.80541972	1139	0.979586449	-0.054343243	normal	0.931633498	0.270201652	normal	0.98107691	-0.00574831	normal	0.773660129	0.072816944	normal	[K]	Transcription	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K03022|1.29122e-148|ptr:745514|POLR3H; polymerase (RNA) III (DNA directed) polypeptide H (22.9kD); K03022 DNA-directed RNA polymerase III subunit RPC8 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase III subunit Rpc25;; SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397	DNA-directed RNA polymerase III subunit RPC8 GN=POLR3H OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC8 [Felis catus] 
ENSG00000100416(TRMU)	--	6.470895813	236	6.969644	245	7.930119	288	7.884529	282	7.804576	274	9.665599	330	0.939236737	0.224736259	normal	0.957285816	0.13915507	normal	0.949303098	0.187186889	normal	0.568621049	0.183905438	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: tRNA adenylyltransferase activity (GO:0004810);; 	K00566|0|pps:100973612|TRMU; tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase; K00566 tRNA-specific 2-thiouridylase [EC:2.8.1.-] (A)	Sulfur relay system (ko04122)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA methyl transferase;; Thiamine biosynthesis protein (ThiI);; NAD synthase;; Asparagine synthase	Mitochondrial tRNA-specific 2-thiouridylase 1 GN=TRMU OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: mitochondrial tRNA-specific 2-thiouridylase 1 isoform X3 [Mustela putorius furo] 
ENSG00000100417(PMM1)	--	19.279906	436	13.58481149	316	19.711	455	14.4906512	336	17.43074256	394	16.5226	365	0.738023872	-0.405067833	normal	0.89837968	0.29557552	normal	0.868462017	-0.325052728	normal	0.600651479	-0.160963266	normal	[R]	General function prediction only	Molecular Function: phosphomannomutase activity (GO:0004615);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: GDP-mannose biosynthetic process (GO:0009298);; 	K17497|0|pps:100987538|PMM1; phosphomannomutase 1; K17497 phosphomannomutase [EC:5.4.2.8] (A)	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[I]	Lipid transport and metabolism	Eukaryotic phosphomannomutase;; haloacid dehalogenase-like hydrolase	Phosphomannomutase 1 GN=PMM1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: phosphomannomutase 1 [Oryctolagus cuniculus]
ENSG00000100418(DESI1)	--	10.5953	702	9.59973	638	12.5109	828	14.4072	955	11.2267	741	10.9028	725	0.679046267	0.412420923	normal	0.953414009	0.194063416	normal	0.954128066	-0.199551408	normal	0.650871941	0.13753147	normal	--	--	--	--	--	[S]	Function unknown	PPPDE putative peptidase domain	Desumoylating isopeptidase 1 GN=DESI1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PPPDE peptidase domain-containing protein 2 [Sus scrofa] 
ENSG00000100422(CERK)	--	9.75569	799	9.85148	817	8.89061	736	13.0934	1076	13.2451	1082	11.2497	924	0.723991674	0.397916966	normal	0.77262756	0.383247722	normal	0.876354291	0.319308891	normal	0.029193738	0.368212655	normal	[IR]	Lipid transport and metabolism;; General function prediction only	Molecular Function: kinase activity (GO:0016301);; 	"K04715|0|hsa:64781|CERK, LK4, dA59H18.2, dA59H18.3, hCERK; ceramide kinase (EC:2.7.1.138); K04715 ceramide kinase [EC:2.7.1.138] (A)"	Sphingolipid metabolism (ko00600)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase catalytic domain	Ceramide kinase GN=CERK OS=Homo sapiens (Human) PE=1 SV=1	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: ceramide kinase [Orcinus orca]
ENSG00000100425(BRD1)	--	5.989867893	526	6.245005864	560	6.148084773	557	7.255692939	645	8.217353154	728	7.830026657	695	0.920981999	0.262710183	normal	0.821860529	0.356239187	normal	0.882392526	0.310288567	normal	0.116183751	0.311015336	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K11349|0|mcf:101926232|uncharacterized LOC101926232; K11349 bromodomain-containing protein 1 (A)	--	[R]	General function prediction only	PHD-zinc-finger like domain;; Enhancer of polycomb-like;; PHD-like zinc-binding domain;; Bromodomain;; PWWP domain;; PHD-finger;; PHD-finger	Bromodomain-containing protein 1 GN=BRD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: bromodomain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000100426(ZBED4)	--	7.118458	940	7.069076	939	6.9137	923	8.27629	1093	7.571146	994	7.667091	1010	0.962233345	0.186445674	normal	0.977272861	0.060599273	normal	0.972968115	0.121470983	normal	0.584775034	0.122925055	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[L]	"Replication, recombination and repair"	BED zinc finger;; hAT family C-terminal dimerisation region	Zinc finger BED domain-containing protein 4 GN=ZBED4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: zinc finger BED domain-containing protein 4 [Tupaia chinensis] 
ENSG00000100429(HDAC10)	--	19.64501122	1337	16.85897487	1196	19.84081129	1322	13.99471545	1039	15.60331641	1138	16.12314174	1265	0.74199413	-0.394120719	normal	0.977691321	-0.093022789	normal	0.980739365	-0.07179227	normal	0.340828115	-0.183972326	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	K18671|0|ggo:101132578|HDAC10; histone deacetylase 10 isoform 1; K18671 histone deacetylase 10 [EC:3.5.1.98] (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain	Histone deacetylase 10 GN=HDAC10 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: histone deacetylase 10 [Galeopterus variegatus]
ENSG00000100433(KCNK10)	--	0	0	0	0	0.408837005	1	0	0	0.020030559	0	0.007581884	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04920|0|hsa:54207|KCNK10, K2p10.1, PPP1R97, TREK-2, TREK2; potassium channel, subfamily K, member 10; K04920 potassium channel subfamily K member 10 (A)"	Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 10 GN=KCNK10 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 10 [Tupaia chinensis]
ENSG00000100439(ABHD4)	--	18.78912198	1204	27.315355	1744	22.87114	1461	23.769705	1518	28.94916608	1839	38.398073	2396	0.908993649	0.303158974	normal	0.984619429	0.055048395	normal	0.004382134	0.704804923	normal	0.369916765	0.363953172	normal	[R]	General function prediction only	--	K13698|0|ptr:452784|ABHD4; abhydrolase domain containing 4; K13698 abhydrolase domain-containing protein 4 (A)	--	[R]	General function prediction only	"Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Platelet-activating factor acetylhydrolase, isoform II"	Abhydrolase domain-containing protein 4 GN=ABHD4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: abhydrolase domain-containing protein 4 isoform X1 [Oryctolagus cuniculus]
ENSG00000100441(KHNYN)	--	18.26149639	1460	20.54151646	1443	16.422609	1248	14.9062018	1228	18.39965817	1341	16.78845902	1347	0.92767333	-0.280168093	normal	0.976982746	-0.127050457	normal	0.978817164	0.101721803	normal	0.638639343	-0.105224414	normal	--	--	--	--	--	[S]	Function unknown	Zc3h12a-like Ribonuclease NYN domain	Protein KHNYN GN=KHNYN OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein KHNYN isoform X1 [Pteropus alecto] 
ENSG00000100442(FKBP3)	--	68.4398	1574	71.7149	1663	74.66	1702	78.4213	1825	70.8034	1622	66.72920005	1535	0.972163062	0.182463146	normal	0.983630513	-0.057388062	normal	0.975724447	-0.157136731	normal	0.981760174	-0.009150164	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09570|2.53776e-162|ptr:452883|FKBP3; FK506 binding protein 3, 25kDa; K09570 FK506-binding protein 3 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase	Peptidyl-prolyl cis-trans isomerase FKBP3 GN=FKBP3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	peptidyl-prolyl cis-trans isomerase FKBP3 [Bos taurus] 
ENSG00000100445(SDR39U1)	--	40.553982	668	37.234765	611	42.30596	686	35.167108	615	36.93522	632	44.776623	759	0.963020012	-0.149734873	normal	0.973129188	0.027259282	normal	0.966813506	0.13731198	normal	0.985385816	0.009369996	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K07071|0|ptr:452823|SDR39U1; short chain dehydrogenase/reductase family 39U, member 1; K07071 (A)"	--	[F]	Nucleotide transport and metabolism	Domain of unknown function (DUF1731);; NAD dependent epimerase/dehydratase family;; NADH(P)-binding	Epimerase family protein SDR39U1 GN=SDR39U1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	Epimerase family protein SDR39U1 [Tupaia chinensis]
ENSG00000100461(RBM23)	--	31.2243215	1120	31.75848684	1153	28.74321965	1162	33.852303	1271	37.93364727	1382	38.31464149	1443	0.971895286	0.151437936	normal	0.949348268	0.239651114	normal	0.907141225	0.303814316	normal	0.196055197	0.233148839	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[K]	Transcription	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; linker between RRM2 and RRM3 domains in RBM39 protein"	Probable RNA-binding protein 23 GN=RBM23 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: probable RNA-binding protein 23 isoform 1 [Dasypus novemcinctus] 
ENSG00000100462(PRMT5)	--	46.3680941	2000	48.38734335	2155	51.60019556	2258	51.27717763	2318	48.04895242	2069	51.20685384	1974	0.976160158	0.181918407	normal	0.985347138	-0.080123392	normal	0.971988064	-0.202070076	normal	0.904382229	-0.033308381	normal	--	--	--	"K02516|0|mcf:101866818|PRMT5, SKB1; Protein arginine N-methyltransferase 5; K02516 protein arginine N-methyltransferase 5 [EC:2.1.1.125] (A)"	RNA transport (ko03013)	[D]	"Cell cycle control, cell division, chromosome partitioning"	PRMT5 arginine-N-methyltransferase	"Protein arginine N-methyltransferase 5, N-terminally processed GN=PRMT5 OS=Homo sapiens (Human) PE=1 SV=4"	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: protein arginine N-methyltransferase 5 isoform 1 [Orcinus orca] 
ENSG00000100473(COCH)	--	18.900779	749	19.71448974	786	19.87107747	787	25.78932158	1019	27.99430206	1084	25.35377301	993	0.678739832	0.412556157	normal	0.593425386	0.441610656	normal	0.868722814	0.326578772	normal	0.017996982	0.393848621	normal	--	--	--	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type A domain;; LCCL domain;; von Willebrand factor type A domain	Cochlin (Precursor) GN=COCH OS=Homo sapiens (Human) PE=1 SV=1	VW	Defense mechanisms;; Extracellular structures	PREDICTED: cochlin [Ailuropoda melanoleuca]
ENSG00000100478(AP4S1)	--	3.144627	204	4.722249002	232	5.012482	242	7.010981522	320	6.220994146	313	6.050716179	313	0.196183399	0.614944594	normal	0.774380966	0.408312247	normal	0.843652588	0.360876047	normal	0.063151572	0.459461039	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K12403|6.83814e-112|pon:100443568|AP4S1; adaptor-related protein complex 4, sigma 1 subunit; K12403 AP-4 complex subunit sigma-1 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	AP-4 complex subunit sigma-1 GN=AP4S1 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-4 complex subunit sigma-1 isoform X5 [Tupaia chinensis] 
ENSG00000100479(POLE2)	--	9.7493311	243	11.645003	259	9.96746	232	7.86329394	203	7.395338	196	5.745246	111	0.915072085	-0.288311129	normal	0.776232634	-0.42069135	normal	0.000321413	-1.061624764	down	0.046135604	-0.548160301	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Biological Process: DNA replication (GO:0006260);; 	"K02325|0|pps:100984667|POLE2; polymerase (DNA directed), epsilon 2, accessory subunit; K02325 DNA polymerase epsilon subunit 2 [EC:2.7.7.7] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; HTLV-I infection (ko05166)	[L]	"Replication, recombination and repair"	DNA polymerase alpha/epsilon subunit B;; DNA polymerases epsilon N terminal	DNA polymerase epsilon subunit 2 GN=POLE2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase epsilon subunit 2 isoform X1 [Capra hircus]
ENSG00000100483(VCPKMT)	--	12.56809161	921	13.8559907	1062	13.99908244	961	9.795107868	850	12.4041153	898	12.58199033	964	0.968174201	-0.146316398	normal	0.931133041	-0.26301512	normal	0.9791719	-0.003788774	normal	0.527901597	-0.139310522	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[A]	RNA processing and modification	Putative methyltransferase	Protein-lysine methyltransferase METTL21D GN=VCPKMT OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: protein-lysine methyltransferase METTL21D [Ursus maritimus] 
ENSG00000100490(CDKL1)	--	2.03059985	73	1.913255	70	1.990465	71	2.299602541	70	2.036591	74	4.019751	56	0.973469296	-0.089450952	normal	0.972609755	0.057534815	normal	0.953654624	-0.342451231	normal	0.873246221	-0.119358731	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08824|0|ptr:100610829|CDKL1; cyclin-dependent kinase-like 1 (CDC2-related kinase); K08824 cyclin-dependent kinase-like [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase-like 1 GN=CDKL1 OS=Homo sapiens (Human) PE=1 SV=5	R	General function prediction only	PREDICTED: cyclin-dependent kinase-like 1 isoform X1 [Pteropus alecto]
ENSG00000100503(NIN)	--	11.57976602	2417	12.82674027	2534	13.82923028	2649	8.437694701	1796	8.37494408	1796	8.556117561	1725	0.541769781	-0.458922543	normal	0.305083847	-0.517686788	normal	0.032098939	-0.626696072	normal	0.000179059	-0.536571086	normal	--	--	--	K16476|0|ptr:452901|NIN; ninein (GSK3B interacting protein); K16476 ninein (A)	--	--	--	EF-hand domain pair;; EF-hand domain	Ninein GN=NIN OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: ninein [Galeopterus variegatus]
ENSG00000100504(PYGL)	--	46.889429	2904	36.53130799	2277	40.64043122	2543	45.98867258	2858	44.91674019	2769	34.26989411	2118	0.989331749	-0.053839086	normal	0.958094262	0.260647015	normal	0.950074862	-0.271942848	normal	0.968742065	-0.018071286	normal	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: glycogen phosphorylase activity (GO:0008184);; 	"K00688|0|ptr:742309|PYGL; phosphorylase, glycogen, liver; K00688 starch phosphorylase [EC:2.4.1.1] (A)"	Starch and sucrose metabolism (ko00500);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Carbohydrate phosphorylase	"Glycogen phosphorylase, liver form GN=PYGL OS=Homo sapiens (Human) PE=1 SV=4"	G	Carbohydrate transport and metabolism	"PREDICTED: glycogen phosphorylase, liver form [Tupaia chinensis]"
ENSG00000100505(TRIM9)	--	5.56246	501	6.998867	654	5.985955	549	3.285733	292	2.794344857	247	2.8608448	258	0.002343647	-0.806392961	normal	1.19E-11	-1.420642278	down	1.08E-06	-1.093227807	down	1.08E-09	-1.118048169	down	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K10649|0|mcf:102146343|TRIM9; tripartite motif containing 9; K10649 tripartite motif-containing protein 9/67 (A)	--	[S]	Function unknown	"SPRY domain;; Fibronectin type III domain;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRIM9 GN=TRIM9 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: E3 ubiquitin-protein ligase TRIM9 isoform X5 [Myotis davidii]
ENSG00000100519(PSMC6)	--	48.948798	1167	47.40042711	1229	48.63828301	1221	48.31593974	1192	48.60714242	1144	44.70642002	1116	0.981434401	-0.00025226	normal	0.975013681	-0.124665378	normal	0.973620004	-0.137838975	normal	0.711480135	-0.088728509	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	"K03064|0|umr:103672921|PSMC6; proteasome (prosome, macropain) 26S subunit, ATPase, 6; K03064 26S proteasome regulatory subunit T4 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA ATPase domain;; AAA domain (Cdc48 subfamily);; AAA domain (dynein-related subfamily);; Holliday junction DNA helicase ruvB N-terminus	26S protease regulatory subunit 10B GN=PSMC6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S protease regulatory subunit 10B [Bos mutus]
ENSG00000100522(GNPNAT1)	--	32.477413	1542	28.03214317	1525	29.66329114	1406	36.74984607	1918	33.86382091	1792	28.69357	1474	0.93338622	0.283713819	normal	0.965064626	0.211141515	normal	0.982506861	0.059785679	normal	0.304373863	0.190730107	normal	[KR]	Transcription;; General function prediction only	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	K00621|2.07305e-117|tup:102493326|GNPNAT1; glucosamine-phosphate N-acetyltransferase 1; K00621 glucosamine-phosphate N-acetyltransferase [EC:2.3.1.4] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	[M]	Cell wall/membrane/envelope biogenesis	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain	Glucosamine 6-phosphate N-acetyltransferase GN=GNPNAT1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	glucosamine 6-phosphate N-acetyltransferase [Bos taurus] 
ENSG00000100523(DDHD1)	--	6.169184298	723	5.692777145	703	6.844692399	819	6.215508043	778	6.823774667	831	4.8524695	574	0.973808225	0.07478902	normal	0.946796204	0.219462595	normal	0.280819996	-0.519951114	normal	0.862816705	-0.062079548	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K13619|0|mcf:102129871|DDHD1; DDHD domain containing 1; K13619 phospholipase DDHD1 [EC:3.1.1.-] (A)	--	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	DDHD domain	Phospholipase DDHD1 GN=DDHD1 OS=Homo sapiens (Human) PE=1 SV=2	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: phospholipase DDHD1 isoform X1 [Loxodonta africana]
ENSG00000100526(CDKN3)	--	59.31061621	749	58.76346871	658	54.84684001	679	50.99877	619	48.790369	603	39.83525042	505	0.888205778	-0.305168706	normal	0.962781006	-0.147003066	normal	0.619781544	-0.434293794	normal	0.13900041	-0.294260987	normal	[T]	Signal transduction mechanisms	Molecular Function: phosphoprotein phosphatase activity (GO:0004721);; Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14167|1.45207e-145|pps:100992867|CDKN3; cyclin-dependent kinase inhibitor 3; K14167 cyclin-dependent kinase inhibitor 3 [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Cyclin-dependent kinase inhibitor 3 (CDKN3);; Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain"	Cyclin-dependent kinase inhibitor 3 GN=CDKN3 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: cyclin-dependent kinase inhibitor 3 [Pteropus alecto]
ENSG00000100528(CNIH1)	--	155.501735	2060	172.0796489	2251	159.2562768	1951	170.3799117	2335	157.2628164	2193	179.9847686	2294	0.980871606	0.149840934	normal	0.986628438	-0.05904661	normal	0.966151471	0.225199027	normal	0.641539133	0.102110468	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Cornichon protein	Protein cornichon homolog 1 GN=CNIH1 OS=Homo sapiens (Human) PE=1 SV=1	OTU	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Protein cornichon-like protein [Bos mutus]
ENSG00000100532(CGRRF1)	--	5.939986453	172	7.94102	199	5.521362961	156	6.264390836	185	6.296724064	183	5.459613662	160	0.965302915	0.073650029	normal	0.957810449	-0.141231705	normal	0.967350897	0.027966727	normal	0.980583949	-0.019186743	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger)"	Cell growth regulator with RING finger domain protein 1 GN=CGRRF1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cell growth regulator with RING finger domain protein 1 [Galeopterus variegatus]
ENSG00000100554(ATP6V1D)	--	24.19882633	687	26.59192613	729	26.69142766	730	31.97298707	916	30.45575631	857	34.327719	988	0.760268284	0.383460377	normal	0.950244673	0.211544734	normal	0.62925499	0.427558988	normal	0.051935179	0.342586615	normal	[C]	Energy production and conversion	"Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; "	"K02149|4.62356e-159|ptr:452979|ATP6V1D; ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; K02149 V-type H+-transporting ATPase subunit D (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase subunit D	V-type proton ATPase subunit D GN=ATP6V1D OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit D [Condylura cristata]
ENSG00000100557(C14orf105)	--	2.195595623	194	2.777882887	233	3.557413566	299	7.888929876	683	8.872246258	680	10.8224815	1006	0	1.777013114	up	3.05E-13	1.517742443	up	0	1.737037187	up	7.04E-06	1.686796435	up	--	--	--	--	--	--	--	Domain of unknown function (DUF4619)	Uncharacterized protein C14orf105 GN=C14orf105 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C14orf105 homolog isoform X2 [Galeopterus variegatus]
ENSG00000100558(PLEK2)	--	1.51915711	42	0.842205005	23	0.995519923	30	18.359889	535	18.18428707	528	6.939591435	202	0	3.593135622	up	0	4.412352121	up	0	2.683067803	up	4.19E-05	3.711639661	up	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	"PH domain;; Pleckstrin homology domain;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; Pleckstrin homology domain;; PH domain"	Pleckstrin-2 GN=PLEK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin-2 isoform X2 [Mustela putorius furo]
ENSG00000100564(PIGH)	--	14.277256	281	8.635255331	187	11.80210896	251	8.5527588	176	11.5515545	246	9.681348	204	0.075631415	-0.700936679	normal	0.850581469	0.371566422	normal	0.904561994	-0.305365043	normal	0.567765871	-0.220260935	normal	--	--	Molecular Function: phosphatidylinositol N-acetylglucosaminyltransferase activity (GO:0017176);; 	"K03858|1.63601e-124|ptr:736276|PIGH; phosphatidylinositol glycan anchor biosynthesis, class H; K03858 phosphatidylinositol glycan, class H (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[MO]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	"GPI-GlcNAc transferase complex, PIG-H component"	Phosphatidylinositol N-acetylglucosaminyltransferase subunit H GN=PIGH OS=Homo sapiens (Human) PE=1 SV=1	MO	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit H [Odobenus rosmarus divergens]
ENSG00000100567(PSMA3)	--	115.216947	1443	114.80359	1449	109.25556	1367	126.703422	1611	130.59668	1632	118.846359	1501	0.978454406	0.127923982	normal	0.975656224	0.150009319	normal	0.977826126	0.126485713	normal	0.519581419	0.134115602	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: endopeptidase activity (GO:0004175);; Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Cellular Component: proteasome core complex, alpha-subunit complex (GO:0019773);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; "	"K02727|1.91061e-177|ptr:467469|PSMA3; proteasome (prosome, macropain) subunit, alpha type, 3; K02727 20S proteasome subunit alpha 7 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome subunit A N-terminal signature	Proteasome subunit alpha type-3 GN=PSMA3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit alpha type-3 isoform 1 [Ovis aries] 
ENSG00000100575(TIMM9)	--	29.640824	458	31.158488	485	30.91998267	475	29.699594	506	25.993573	398	29.998049	485	0.965229343	0.112598076	normal	0.887556328	-0.30558907	normal	0.971231585	0.021697428	normal	0.884470606	-0.051237655	normal	--	--	--	K17777|3.38152e-60|umr:103673420|TIMM9; translocase of inner mitochondrial membrane 9 homolog (yeast); K17777 mitochondrial import inner membrane translocase subunit TIM9 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim10/DDP family zinc finger	Mitochondrial import inner membrane translocase subunit Tim9 GN=TIMM9 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim9 isoformX1 [Canis lupus familiaris] 
ENSG00000100577(GSTZ1)	--	22.28325157	403	23.19727398	472	21.85674051	426	15.50974006	300	13.00953301	264	20.66066502	365	0.617788601	-0.454632421	normal	0.001132012	-0.855954554	normal	0.935558579	-0.230363991	normal	0.016432256	-0.506604706	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K01800|1.04555e-155|ptr:453068|GSTZ1; glutathione S-transferase zeta 1; K01800 maleylacetoacetate isomerase [EC:5.2.1.2] (A)	Tyrosine metabolism (ko00350)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Maleylacetoacetate isomerase GN=GSTZ1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: maleylacetoacetate isomerase isoform X1 [Felis catus]
ENSG00000100578(KIAA0586)	--	6.514092842	486	6.391894249	507	8.124708988	501	7.272844048	610	6.322795707	560	8.327051571	627	0.894992113	0.29618344	normal	0.964534878	0.121669113	normal	0.877216478	0.314513085	normal	0.263814332	0.245271123	normal	--	--	Biological Process: smoothened signaling pathway (GO:0007224);; 	--	--	--	--	Hedgehog signalling target	Protein TALPID3 GN=KIAA0586 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein TALPID3 [Equus caballus]
ENSG00000100580(TMED8)	--	7.94617	1003	7.7991	1001	9.15201	1158	8.42103	1076	9.07428	1141	6.55089	830	0.97811027	0.070420052	normal	0.967127228	0.167193545	normal	0.383780593	-0.487987115	normal	0.800513651	-0.075015224	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Golgi-dynamics membrane-trafficking	Protein TMED8 GN=TMED8 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein TMED8 [Dasypus novemcinctus]
ENSG00000100583(SAMD15)	--	1.436348	98	1.547074	118	1.392844044	124	2.1124541	101	1.364905345	122	1.019058	89	0.971054833	0.012476698	normal	0.967785424	0.026335794	normal	0.835482255	-0.479815265	normal	0.792791575	-0.145181025	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Sterile alpha motif domain-containing protein 15 GN=SAMD15 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: sterile alpha motif domain-containing protein 15 [Ceratotherium simum simum]
ENSG00000100591(AHSA1)	--	99.20894773	2924	103.2410304	3134	119.1994304	3582	108.6890374	3238	98.4528914	2851	86.6006448	2566	0.98740985	0.11626934	normal	0.983604452	-0.157883783	normal	0.440946926	-0.489290371	normal	0.357950452	-0.177110297	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATPase activator activity (GO:0001671);; Biological Process: response to stress (GO:0006950);; Molecular Function: chaperone binding (GO:0051087);; 	--	--	[S]	Function unknown	"Activator of Hsp90 ATPase, N-terminal;; Activator of Hsp90 ATPase homolog 1-like protein"	Activator of 90 kDa heat shock protein ATPase homolog 1 GN=AHSA1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: activator of 90 kDa heat shock protein ATPase homolog 1 [Galeopterus variegatus]
ENSG00000100592(DAAM1)	--	2.706946615	296	2.990553757	335	2.412008483	270	4.553229447	511	2.978415101	339	4.120594645	462	0.00752891	0.753881686	normal	0.967564797	-0.004283159	normal	0.007745043	0.763335268	normal	0.062025575	0.520175493	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	K04512|0|myb:102255808|DAAM1; dishevelled associated activator of morphogenesis 1; K04512 dishevelled associated activator of morphogenesis (A)	Wnt signaling pathway (ko04310)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain	Disheveled-associated activator of morphogenesis 1 GN=DAAM1 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: disheveled-associated activator of morphogenesis 1 isoform X2 [Eptesicus fuscus]
ENSG00000100593(ISM2)	--	0.510044929	23	0.754373414	41	0.383707956	24	0.268092549	15	0.113880714	6	0.096293169	6	0.977058722	-0.597711125	normal	0.000261389	-2.519445671	down	0.428948294	-1.77107928	normal	0.008576087	-1.72965359	down	--	--	--	--	--	--	--	AMOP domain;; Thrombospondin type 1 domain	Isthmin-2 (Precursor) GN=ISM2 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: isthmin-2 [Balaenoptera acutorostrata scammoni]
ENSG00000100596(SPTLC2)	--	9.986152394	1404	10.1445159	1420	9.892722777	1269	13.94716343	1971	12.27039656	1687	10.8063576	1491	0.527955275	0.458127679	normal	0.958914542	0.226920542	normal	0.95723258	0.224050174	normal	0.080030197	0.308891464	normal	[H]	Coenzyme transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00654|0|hsa:9517|SPTLC2, HSN1C, LCB2, LCB2A, NSAN1C, SPT2, hLCB2a; serine palmitoyltransferase, long chain base subunit 2 (EC:2.3.1.50); K00654 serine palmitoyltransferase [EC:2.3.1.50] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[O]	"Posttranslational modification, protein turnover, chaperones"	Aminotransferase class I and II;; Beta-eliminating lyase	Serine palmitoyltransferase 2 GN=SPTLC2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine palmitoyltransferase 2 [Oryctolagus cuniculus]
ENSG00000100599(RIN3)	--	15.85802204	1309	15.99821576	1311	17.60069105	1445	17.72929074	1452	19.40585468	1573	15.61143176	1336	0.978052998	0.118611872	normal	0.951849859	0.241170162	normal	0.977953954	-0.121308853	normal	0.736290517	0.080214519	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar sorting protein 9 (VPS9) domain	Ras and Rab interactor 3 GN=RIN3 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras and Rab interactor 3 [Chrysochloris asiatica]
ENSG00000100600(LGMN)	--	40.77635086	1605	34.90516946	1363	34.40436319	1324	34.538172	1333	41.75902999	1648	37.88467568	1421	0.916142744	-0.29841477	normal	0.948090112	0.252249276	normal	0.980122702	0.093608765	normal	0.965782714	0.015435011	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; 	"K01369|0|hsa:5641|LGMN, AEP, LGMN1, PRSC1; legumain (EC:3.4.22.34); K01369 legumain [EC:3.4.22.34] (A)"	Lysosome (ko04142);; Antigen processing and presentation (ko04612)	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase C13 family	Legumain (Precursor) GN=LGMN OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: legumain [Felis catus]
ENSG00000100601(ALKBH1)	--	4.668017715	203	4.37710707	189	5.497534152	238	5.298084635	234	6.448182679	281	6.914181398	303	0.953468024	0.172976445	normal	0.442908566	0.547145391	normal	0.870456974	0.338156094	normal	0.206267068	0.356732225	normal	--	--	--	"K10765|0|hsa:8846|ALKBH1, ABH, ABH1, ALKBH, alkB, hABH; alkB, alkylation repair homolog 1 (E. coli) (EC:4.2.99.18 1.14.11.33); K10765 alkylated DNA repair protein alkB homolog 1 [EC:1.14.11.- 4.2.99.18] (A)"	--	[A]	RNA processing and modification	2OG-Fe(II) oxygenase superfamily	Alkylated DNA repair protein alkB homolog 1 GN=ALKBH1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: alkylated DNA repair protein alkB homolog 1 [Ailuropoda melanoleuca] 
ENSG00000100603(SNW1)	--	32.60058376	1563	32.63796153	1573	30.80238655	1472	30.45809387	1445	31.11900745	1482	29.4643952	1410	0.976409137	-0.143933342	normal	0.980025739	-0.107293487	normal	0.982058975	-0.070300149	normal	0.623059952	-0.108796269	normal	--	--	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Cellular Component: spliceosomal complex (GO:0005681);; "	K06063|0|mcf:101864794|uncharacterized LOC101864794; K06063 SNW domain-containing protein 1 (A)	Spliceosome (ko03040);; Notch signaling pathway (ko04330);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[AB]	RNA processing and modification;; Chromatin structure and dynamics	SKIP/SNW domain	SNW domain-containing protein 1 GN=SNW1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: SNW domain-containing protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000100604(CHGA)	--	0.247574228	12	0.256627966	13	0.327954243	16	0.223102973	11	0.080249364	3	0.3111774	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: secretory granule (GO:0030141);; 	--	--	--	--	Granin (chromogranin or secretogranin)	ER-37 (Precursor) GN=CHGA OS=Homo sapiens (Human) PE=1 SV=7	R	General function prediction only	PREDICTED: chromogranin-A [Balaenoptera acutorostrata scammoni]
ENSG00000100605(ITPK1)	--	37.74216928	1727	37.46673751	1492	36.87773995	1710	47.83691139	2009	49.12109442	2115	42.55294505	1898	0.972836311	0.187222682	normal	0.453238761	0.481571701	normal	0.979189101	0.142072916	normal	0.112519697	0.267773728	normal	--	--	"Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: intracellular (GO:0005622);; Biological Process: inositol trisphosphate metabolic process (GO:0032957);; Molecular Function: inositol tetrakisphosphate 1-kinase activity (GO:0047325);; Molecular Function: inositol-1,3,4-trisphosphate 6-kinase activity (GO:0052725);; Molecular Function: inositol-1,3,4-trisphosphate 5-kinase activity (GO:0052726);; "	"K00913|0|hsa:3705|ITPK1, ITRPK1; inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159); K00913 inositol-1,3,4-trisphosphate 5/6-kinase / inositol-tetrakisphosphate 1-kinase [EC:2.7.1.159 2.7.1.134] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	--	--	"Inositol 1, 3, 4-trisphosphate 5/6-kinase"	Inositol-tetrakisphosphate 1-kinase GN=ITPK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inositol-tetrakisphosphate 1-kinase [Galeopterus variegatus]
ENSG00000100612(DHRS7)	--	46.32259525	1009	54.79684233	1173	48.47470856	1027	47.6856005	1046	55.0043027	1161	55.84258747	1203	0.97969738	0.021092869	normal	0.980432098	-0.036214669	normal	0.954239065	0.21960994	normal	0.796583116	0.066762087	normal	[R]	General function prediction only	--	"K11165|0|hsa:51635|DHRS7, SDR34C1, retDSR4, retSDR4; dehydrogenase/reductase (SDR family) member 7; K11165 dehydrogenase/reductase SDR family member 7 [EC:1.1.-.-] (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Dehydrogenase/reductase SDR family member 7 (Precursor) GN=DHRS7 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 7 isoform 1 [Dasypus novemcinctus]
ENSG00000100614(PPM1A)	--	17.01684	1190	14.37395193	1210	16.16393981	1242	17.07227	1194	16.970404	1264	18.3492794	1319	0.981323454	-0.025957543	normal	0.980961254	0.041512095	normal	0.980256032	0.07839531	normal	0.912000575	0.031690051	normal	[T]	Signal transduction mechanisms	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: phosphoprotein phosphatase activity (GO:0004721);; Molecular Function: manganese ion binding (GO:0030145);; 	"K04457|0|pps:100970419|PPM1A; protein phosphatase, Mg2+/Mn2+ dependent, 1A; K04457 protein phosphatase 1A [EC:3.1.3.16] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	"Protein phosphatase 2C;; Protein serine/threonine phosphatase 2C, C-terminal domain"	Protein phosphatase 1A GN=PPM1A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1A isoform X1 [Vicugna pacos]
ENSG00000100625(SIX4)	--	3.175434	273	2.798330115	241	3.1137434	274	2.365952036	197	3.029168686	268	2.63111963	229	0.584840785	-0.498220436	normal	0.958394731	0.130993563	normal	0.923616241	-0.265514494	normal	0.534545887	-0.20376224	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15615|0|hsa:51804|SIX4, AREC3; SIX homeobox 4; K15615 homeobox protein SIX4 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Homeobox domain;; Homeobox KN domain	Homeobox protein SIX4 GN=SIX4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein SIX4 [Leptonychotes weddellii]
ENSG00000100626(GALNT16)	--	1.244092695	111	1.2202676	100	1.0629993	90	2.122060379	168	2.126555	171	1.565856141	124	0.614450846	0.56072092	normal	0.167139273	0.743871701	normal	0.865286322	0.44761825	normal	0.078515282	0.599019985	normal	--	--	--	"K00710|0|ptr:467488|GALNT16, GALNTL1; polypeptide N-acetylgalactosaminyltransferase 16; K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 16 GN=GALNT16 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 16 [Ochotona princeps]
ENSG00000100628(ASB2)	--	0.50954134	22	0.29535141	13	0.445958337	20	0.320125188	14	0.379096319	17	0.250021683	11	0.977095772	-0.627540758	normal	--	--	--	0.97131957	-0.789314314	normal	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K10324|0|hsa:51676|ASB2, ASB-2; ankyrin repeat and SOCS box containing 2; K10324 ankyrin repeat and SOCS box protein 2 (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 2 GN=ASB2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 2 [Chrysochloris asiatica]
ENSG00000100629(CEP128)	--	3.069478606	335	4.1017339	414	3.745230361	399	3.516769	303	2.976039482	291	2.825905571	309	0.952070111	-0.174831949	normal	0.38267285	-0.527726089	normal	0.804974432	-0.375451741	normal	0.123020523	-0.367401963	normal	--	--	--	"K16460|0|hsa:145508|CEP128, C14orf145, C14orf61, LEDP/132; centrosomal protein 128kDa; K16460 centrosomal protein CEP128 (A)"	--	--	--	--	Centrosomal protein of 128 kDa GN=CEP128 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 128 kDa isoform X2 [Equus przewalskii]
ENSG00000100632(ERH)	--	174.156845	2737	193.23598	3053	186.146331	2929	231.556252	3710	211.47751	3319	188.65458	2975	0.78118473	0.407794217	normal	0.988335026	0.099047419	normal	0.990067048	0.014182767	normal	0.352394341	0.176478785	normal	--	--	Biological Process: pyrimidine nucleotide biosynthetic process (GO:0006221);; Biological Process: cell cycle (GO:0007049);; Biological Process: positive regulation of Notch signaling pathway (GO:0045747);; 	--	--	[R]	General function prediction only	Enhancer of rudimentary	Enhancer of rudimentary homolog GN=ERH OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: enhancer of rudimentary homolog [Dasypus novemcinctus]
ENSG00000100644(HIF1A)	--	160.95287	10792	135.544	8954	140.5871	9182	179.7814573	12060	233.8722584	15631	211.7405246	14202	0.995238957	0.129417955	normal	0.001146242	0.782278072	normal	0.079803321	0.620839478	normal	0.004620462	0.513527497	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K08268|0|hsa:3091|HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78; hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor); K08268 hypoxia-inducible factor 1 alpha (A)"	HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; Thyroid hormone signaling pathway (ko04919);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Renal cell carcinoma (ko05211);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[TK]	Signal transduction mechanisms;; Transcription	PAS domain;; PAS fold;; HIF-1 alpha C terminal transactivation domain;; Hypoxia-inducible factor-1;; PAS fold;; PAS domain;; PAS fold	Hypoxia-inducible factor 1-alpha GN=HIF1A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hypoxia-inducible factor 1-alpha isoform 1 [Trichechus manatus latirostris]
ENSG00000100647(SUSD6)	--	3.972316	373	4.523759499	433	4.119368	387	4.53596793	429	4.797104	447	5.71474059	538	0.953976233	0.170315231	normal	0.969507855	0.024397385	normal	0.53872873	0.465431905	normal	0.365625997	0.224567761	normal	--	--	--	--	--	--	--	Sushi domain (SCR repeat)	Uncharacterized protein KIAA0247 (Precursor) GN=KIAA0247 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA0247 homolog isoform X1 [Tupaia chinensis] 
ENSG00000100650(SRSF5)	--	106.7743461	2846	106.3775846	2834	99.110293	2551	97.990838	2577	117.9300773	3203	87.005342	2264	0.980704637	-0.173976628	normal	0.983966818	0.155079605	normal	0.978104459	-0.180366809	normal	0.873271495	-0.054738232	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12893|1.05911e-94|asn:102379116|SRSF5; serine/arginine-rich splicing factor 5; K12893 splicing factor, arginine/serine-rich 4/5/6 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Serine/arginine-rich splicing factor 5 GN=SRSF5 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"PREDICTED: serine/arginine-rich splicing factor 5-like, partial [Sus scrofa]"
ENSG00000100652(SLC10A1)	--	0	0	0.0290082	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Cellular Component: membrane (GO:0016020);; 	"K14341|0|hsa:6554|SLC10A1, NTCP; solute carrier family 10 (sodium/bile acid cotransporter), member 1; K14341 solute carrier family 10 (sodium/bile acid cotransporter), member 1 (A)"	Bile secretion (ko04976)	[P]	Inorganic ion transport and metabolism	Sodium Bile acid symporter family;; SBF-like CPA transporter family (DUF4137)	Sodium/bile acid cotransporter GN=SLC10A1 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/bile acid cotransporter isoform X1 [Equus caballus]
ENSG00000100664(EIF5)	--	92.50351893	4652	84.03740517	3891	87.08282	4009	115.1054215	5637	126.4720751	6548	102.0527251	4817	0.977551853	0.24617026	normal	0.003530164	0.729265964	normal	0.972044379	0.256512673	normal	0.045853937	0.416202409	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation initiation factor activity (GO:0003743);; Molecular Function: protein binding (GO:0005515);; Biological Process: translational initiation (GO:0006413);; 	"K03262|0|hsa:1983|EIF5, EIF-5, EIF-5A; eukaryotic translation initiation factor 5; K03262 translation initiation factor 5 (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Domain found in IF2B/IF5;; eIF4-gamma/eIF5/eIF2-epsilon	Eukaryotic translation initiation factor 5 GN=EIF5 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 5 [Chrysochloris asiatica]
ENSG00000100665(SERPINA4)	--	0.169562972	1	0	0	0	0	0.023428251	1	0.42169715	12	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Kallistatin (Precursor) GN=SERPINA4 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: LOW QUALITY PROTEIN: kallistatin [Galeopterus variegatus]
ENSG00000100678(SLC8A3)	--	0	0	0	0	0	0	0.01734364	1	0	0	0.014746055	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell communication (GO:0007154);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K05849|0|ptr:467491|SLC8A3; solute carrier family 8 (sodium/calcium exchanger), member 3; K05849 solute carrier family 8 (sodium/calcium exchanger) (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Protein digestion and absorption (ko04974)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Calx-beta domain;; Sodium/calcium exchanger protein	Sodium/calcium exchanger 3 (Precursor) GN=SLC8A3 OS=Homo sapiens (Human) PE=2 SV=2	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: sodium/calcium exchanger 3 isoform X1 [Tupaia chinensis]
ENSG00000100697(DICER1)	--	14.41681015	2187	14.28278092	2354	13.07903325	2178	11.4941338	1996	13.54137095	2085	12.355562	1994	0.97865472	-0.162554165	normal	0.973891779	-0.196359356	normal	0.981744635	-0.135531599	normal	0.38647819	-0.166617148	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ribonuclease III activity (GO:0004525);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: RNA processing (GO:0006396);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: endoribonuclease activity, producing 5'-phosphomonoesters (GO:0016891);; "	K11592|0|ggo:101124693|DICER1; endoribonuclease Dicer isoform 1; K11592 endoribonuclease Dicer [EC:3.1.26.-] (A)	MicroRNAs in cancer (ko05206)	[A]	RNA processing and modification	"Ribonuclease III domain;; PAZ domain;; Dicer dimerisation domain;; Ribonuclease-III-like;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; Type III restriction enzyme, res subunit"	Endoribonuclease Dicer GN=DICER1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: endoribonuclease Dicer [Galeopterus variegatus]
ENSG00000100711(ZFYVE21)	--	17.61214	388	17.70495	402	21.401612	467	25.72211	568	22.13556	487	21.74991	481	0.341319733	0.51729994	normal	0.923888038	0.254429	normal	0.970798943	0.03421373	normal	0.239088943	0.267753778	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	FYVE zinc finger	Zinc finger FYVE domain-containing protein 21 GN=ZFYVE21 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger FYVE domain-containing protein 21 isoform X1 [Galeopterus variegatus]
ENSG00000100714(MTHFD1)	--	65.392517	3646	70.785628	4067	75.292957	4120	76.382733	4482	70.691742	4148	64.622888	3917	0.966984237	0.266894242	normal	0.992068079	0.00702176	normal	0.991045798	-0.081156096	normal	0.801265235	0.063020191	normal	[F]	Nucleotide transport and metabolism	Molecular Function: formate-tetrahydrofolate ligase activity (GO:0004329);; Molecular Function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488);; Molecular Function: ATP binding (GO:0005524);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00288|0|ptr:452965|MTHFD1; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase; K00288 methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3] (A)"	One carbon pool by folate (ko00670)	[H]	Coenzyme transport and metabolism	"Formate--tetrahydrofolate ligase;; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain;; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain"	"C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed GN=MTHFD1 OS=Homo sapiens (Human) PE=1 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: c-1-tetrahydrofolate synthase, cytoplasmic [Condylura cristata]"
ENSG00000100722(ZC3H14)	--	30.96658056	1554	34.02683818	1726	32.21424546	1568	33.71528592	1606	30.3157261	1537	29.736614	1471	0.984498499	0.016636946	normal	0.97012726	-0.188566655	normal	0.980880862	-0.100319841	normal	0.686594367	-0.092927048	normal	--	--	--	--	--	[A]	RNA processing and modification	Zinc finger C-x8-C-x5-C-x3-H type	Zinc finger CCCH domain-containing protein 14 GN=ZC3H14 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: zinc finger CCCH domain-containing protein 14 isoform 1 [Ceratotherium simum simum]
ENSG00000100726(TELO2)	--	12.0184	757	10.775806	652	11.1138	731	12.652706	779	11.0337	692	10.302517	621	0.976421865	0.010476803	normal	0.9725695	0.064328676	normal	0.934475895	-0.243023457	normal	0.857800023	-0.054513325	normal	--	--	--	"K11137|0|hsa:9894|TELO2, CLK2, TEL2; telomere maintenance 2; K11137 telomere length regulation protein (A)"	Fanconi anemia pathway (ko03460)	[S]	Function unknown	Telomere length regulation protein	Telomere length regulation protein TEL2 homolog GN=TELO2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: telomere length regulation protein TEL2 homolog [Ceratotherium simum simum]
ENSG00000100731(PCNX1)	--	12.125135	1936	12.86921977	1929	11.59499681	1769	12.18767021	2138	14.39141582	2274	11.37130763	1906	0.983399385	0.112265836	normal	0.968546702	0.215796594	normal	0.983163497	0.09924088	normal	0.476322227	0.143691716	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Pecanex protein (C-terminus)	Pecanex-like protein 1 GN=PCNX OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: pecanex-like protein 1-like isoform X1 [Elephantulus edwardii]
ENSG00000100739(BDKRB1)	--	12.92390001	820	8.109454364	671	7.59778618	545	3.931312168	290	7.793872641	528	6.267846443	478	1.33E-14	-1.52537041	down	0.803931799	-0.366268334	normal	0.94920689	-0.196953043	normal	0.075885511	-0.671844115	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K03915|0|hsa:623|BDKRB1, B1BKR, B1R, BDKRB2, BKB1R, BKR1, BRADYB1; bradykinin receptor B1; K03915 bradykinin receptor B1 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Complement and coagulation cascades (ko04610);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srw	B1 bradykinin receptor GN=BDKRB1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: B1 bradykinin receptor [Galeopterus variegatus]
ENSG00000100744(GSKIP)	--	15.187315	476	14.23997	453	15.978108	493	20.70837	641	18.21967	568	18.293305	552	0.731327693	0.397421617	normal	0.888668107	0.304045205	normal	0.95982513	0.154341537	normal	0.17616983	0.286919147	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF727)	GSK3-beta interaction protein GN=GSKIP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: GSK3-beta interaction protein [Tupaia chinensis]
ENSG00000100749(VRK1)	--	14.69717575	455	14.68327749	466	14.73497363	463	15.85482712	507	14.51127116	453	11.1921665	354	0.963627013	0.124887319	normal	0.968451899	-0.062041244	normal	0.758885656	-0.394077645	normal	0.755021989	-0.097100694	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08816|0|hsa:7443|VRK1, PCH1, PCH1A; vaccinia related kinase 1 (EC:2.7.11.1); K08816 vaccinia related kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase VRK1 GN=VRK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase VRK1 isoform X2 [Galeopterus variegatus]
ENSG00000100764(PSMC1)	--	42.7637	1868	48.7990847	2193	49.3105908	2114	53.2017392	2393	51.8413278	2267	43.02827438	1797	0.903960804	0.32625609	normal	0.987353696	0.026434093	normal	0.958522651	-0.242488042	normal	0.887313641	0.042473226	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	"K03062|0|shr:100932408|PSMC1; proteasome (prosome, macropain) 26S subunit, ATPase, 1; K03062 26S proteasome regulatory subunit T2 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA domain (Cdc48 subfamily);; AAA domain (dynein-related subfamily);; Protein of unknown function (DUF815);; Holliday junction DNA helicase ruvB N-terminus	26S protease regulatory subunit 4 GN=PSMC1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: 26S protease regulatory subunit 4 [Sarcophilus harrisii]
ENSG00000100767(PAPLN)	--	2.990453249	275	2.8337537	284	2.976986159	302	1.906971351	188	2.16905424	235	2.005065895	209	0.346268896	-0.575615909	normal	0.906780406	-0.292939008	normal	0.439671718	-0.53609148	normal	0.068513467	-0.466748759	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Molecular Function: peptidase activity (GO:0008233);; 	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; ADAM-TS Spacer 1;; Immunoglobulin domain;; Thrombospondin type 1 domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Kunitz/Bovine pancreatic trypsin inhibitor domain;; PLAC (protease and lacunin) domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Papilin (Precursor) GN=PAPLN OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: papilin [Camelus dromedarius]
ENSG00000100784(RPS6KA5)	--	4.520683085	326	2.40315268	169	4.205473529	305	3.22517325	243	2.849219003	202	3.416379354	249	0.665336888	-0.452268987	normal	0.939882284	0.233988259	normal	0.90177586	-0.299309501	normal	0.683826939	-0.225754774	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K04445|0|pps:100971222|RPS6KA5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; K04445 ribosomal protein S6 kinase alpha-5 [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Circadian entrainment (ko04713);; Neurotrophin signaling pathway (ko04722);; MicroRNAs in cancer (ko05206);; Bladder cancer (ko05219)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family;; Phosphotransferase enzyme family;; Protein kinase C terminal domain;; RIO1 family	Ribosomal protein S6 kinase alpha-5 GN=RPS6KA5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ribosomal protein S6 kinase alpha-5 [Balaenoptera acutorostrata scammoni]
ENSG00000100796(PPP4R3A)	--	34.328747	1787	43.88769841	2181	36.17442895	1945	38.977477	2092	38.899966	2176	45.30632	2358	0.971616135	0.196354806	normal	0.9871671	-0.024720611	normal	0.949080372	0.269311668	normal	0.480271312	0.143342898	normal	--	--	--	"K17491|0|ptr:739423|SMEK1; SMEK homolog 1, suppressor of mek1 (Dictyostelium); K17491 protein phosphatase 4 regulatory subunit 3 (A)"	--	[G]	Carbohydrate transport and metabolism	Component of IIS longevity pathway SMK-1	Serine/threonine-protein phosphatase 4 regulatory subunit 3A GN=SMEK1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3A isoform X1 [Galeopterus variegatus]
ENSG00000100802(C14orf93)	--	7.5543971	189	8.202009936	145	7.525284325	198	4.905478744	135	6.108736328	155	5.93089626	159	0.671506779	-0.511315261	normal	0.964802807	0.074041796	normal	0.905672636	-0.322014816	normal	0.486792329	-0.265013917	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4616)	Uncharacterized protein C14orf93 (Precursor) GN=C14orf93 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C14orf93 homolog [Galeopterus variegatus]
ENSG00000100804(PSMB5)	--	144.022932	2593	144.50698	2652	141.536083	2619	116.250682	2155	116.234601	2073	115.10028	2111	0.934799357	-0.297572851	normal	0.839099817	-0.376543669	normal	0.916464126	-0.319175223	normal	0.035889847	-0.332277497	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02737|4.46185e-166|pps:100988289|PSMB5; proteasome (prosome, macropain) subunit, beta type, 5; K02737 20S proteasome subunit beta 5 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-5 (Precursor) GN=PSMB5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-5 isoform X1 [Oryctolagus cuniculus]
ENSG00000100811(YY1)	--	23.679418	2582	29.197624	2944	22.525799	2579	28.349667	3003	28.353971	3043	25.029044	2677	0.979215837	0.186979971	normal	0.989789695	0.026276828	normal	0.988760884	0.045487742	normal	0.715293745	0.084369773	normal	[R]	General function prediction only	--	K09201|4.73259e-33|lcm:102355391|transcriptional repressor protein YY1-like; K09201 transcription factor YY (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type"	Transcriptional repressor protein YY1 GN=YY1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	hypothetical protein CB1_000726017 [Camelus ferus]
ENSG00000100813(ACIN1)	--	36.81290865	4033	39.88307939	4406	40.26757138	4388	39.54867747	4012	43.49174621	4647	40.98152818	4762	0.991968964	-0.038349415	normal	0.992183131	0.055385081	normal	0.990935155	0.10967636	normal	0.873246221	0.044717106	normal	--	--	--	K12875|0|ggo:101130589|ACIN1; apoptotic chromatin condensation inducer in the nucleus isoform 1; K12875 apoptotic chromatin condensation inducer in the nucleus (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040)	[B]	Chromatin structure and dynamics	"SAP domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Apoptotic chromatin condensation inducer in the nucleus GN=ACIN1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: apoptotic chromatin condensation inducer in the nucleus isoform 1 [Orcinus orca]
ENSG00000100814(CCNB1IP1)	--	22.37258873	497	21.46646217	473	21.05944538	453	26.32339449	584	27.04477458	574	26.72022221	582	0.948204261	0.201315678	normal	0.923510509	0.25703702	normal	0.82716872	0.352176834	normal	0.2150146	0.268838707	normal	--	--	--	"K10639|0|hsa:57820|CCNB1IP1, C14orf18, HEI10; cyclin B1 interacting protein 1, E3 ubiquitin protein ligase; K10639 E3 ubiquitin-protein ligase CCNP1IP1 [EC:6.3.2.19] (A)"	--	--	--	zinc-RING finger domain	E3 ubiquitin-protein ligase CCNB1IP1 GN=CCNB1IP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase CCNB1IP1 [Camelus ferus] 
ENSG00000100823(APEX1)	--	122.667976	3298	123.9495096	3362	119.78982	3270	134.5636984	3630	133.215778	3573	153.578341	4086	0.988916171	0.107498141	normal	0.990156744	0.066360674	normal	0.940217076	0.312977386	normal	0.402102147	0.164163541	normal	[L]	"Replication, recombination and repair"	--	"K10771|0|hsa:328|APEX1, APE, APE1, APEN, APEX, APX, HAP1, REF1; APEX nuclease (multifunctional DNA repair enzyme) 1 (EC:4.2.99.18); K10771 AP endonuclease 1 [EC:4.2.99.18] (A)"	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	Endonuclease/Exonuclease/phosphatase family;; Endonuclease-reverse transcriptase	"DNA-(apurinic or apyrimidinic site) lyase, mitochondrial GN=APEX1 OS=Homo sapiens (Human) PE=1 SV=2"	L	"Replication, recombination and repair"	APEX nuclease (multifunctional DNA repair enzyme) 1 [Panthera tigris altaica] 
ENSG00000100836(PABPN1)	--	106.0902383	3980	109.4799901	4196	103.5745478	3925	106.564498	3840	107.3444894	3805	107.8872834	4008	0.990841355	-0.082461971	normal	0.986339752	-0.162483255	normal	0.992021052	0.021890066	normal	0.75454531	-0.075576079	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K14396|1.54831e-112|ngi:103739461|Pabpn1; poly(A) binding protein, nuclear 1; K14396 polyadenylate-binding protein 2 (A)"	mRNA surveillance pathway (ko03015);; Influenza A (ko05164)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Polyadenylate-binding protein 2 GN=PABPN1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PABPN1 protein [Bos taurus]
ENSG00000100852(ARHGAP5)	--	26.67192115	2235	34.47442005	2755	28.0653535	2307	36.69245419	3281	30.83338912	2696	38.92118857	3296	0.27534105	0.522730297	normal	0.988608908	-0.052629175	normal	0.350634765	0.506127799	normal	0.068071316	0.324284374	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: signal transduction (GO:0007165);; 	K13709|0|ptr:467419|ARHGAP5; Rho GTPase activating protein 5; K13709 Rho GTPase-activating protein 5 (A)	Focal adhesion (ko04510);; Leukocyte transendothelial migration (ko04670)	[T]	Signal transduction mechanisms	RhoGAP domain;; FF domain;; Ras family	Rho GTPase-activating protein 5 GN=ARHGAP5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 5 [Ceratotherium simum simum]
ENSG00000100865(CINP)	--	29.62033973	529	32.63359833	598	28.4343418	551	31.20807008	597	29.36721474	552	26.9822979	534	0.962510647	0.143239179	normal	0.963311334	-0.136544242	normal	0.971419305	-0.053355258	normal	0.967880881	-0.017313147	normal	--	--	--	--	--	--	--	--	Cyclin-dependent kinase 2-interacting protein GN=CINP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-dependent kinase 2-interacting protein [Galeopterus variegatus]
ENSG00000100867(DHRS2)	--	0.902465501	26	0.31625093	10	0.3251276	9	1.171653229	33	1.481154728	40	0.419003777	13	0.980662195	0.297490702	normal	0.025525757	1.830735322	normal	--	--	--	0.388731016	0.910539666	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K11164|5.76322e-179|pon:100447363|DHRS2; dehydrogenase/reductase SDR family member 2; K11164 dehydrogenase/reductase SDR family member 2 [EC:1.1.-.-] (A)	--	[R]	General function prediction only	Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase;; KR domain	"Dehydrogenase/reductase SDR family member 2, mitochondrial (Precursor) GN=DHRS2 OS=Homo sapiens (Human) PE=1 SV=4"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 2 isoform X2 [Condylura cristata]
ENSG00000100883(SRP54)	--	39.42237918	1540	40.88405324	1609	39.57849666	1533	37.9760528	1474	36.47280928	1404	37.83508841	1468	0.981191409	-0.093930288	normal	0.961187213	-0.217828572	normal	0.982494465	-0.070725866	normal	0.542395782	-0.128713869	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTP binding (GO:0005525);; Biological Process: SRP-dependent cotranslational protein targeting to membrane (GO:0006614);; Molecular Function: 7S RNA binding (GO:0008312);; Cellular Component: signal recognition particle (GO:0048500);; 	K03106|0|umr:103666143|SRP54; signal recognition particle 54kDa; K03106 signal recognition particle subunit SRP54 (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"SRP54-type protein, GTPase domain;; Signal peptide binding domain;; SRP54-type protein, helical bundle domain;; CobW/HypB/UreG, nucleotide-binding domain;; AAA domain;; CobQ/CobB/MinD/ParA nucleotide binding domain;; Molybdopterin guanine dinucleotide synthesis protein B;; Signal recognition particle receptor beta subunit"	Signal recognition particle 54 kDa protein GN=SRP54 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle 54 kDa protein [Leptonychotes weddellii]
ENSG00000100888(CHD8)	--	15.413064	2793	16.31323372	2883	17.43454568	2740	17.05033915	3011	20.02160201	3442	17.29150598	3023	0.988692379	0.077553778	normal	0.971810145	0.234137179	normal	0.985581023	0.1334435	normal	0.454045911	0.149968248	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on acid anhydrides (GO:0016817);; "	"K04494|0|hsa:57680|CHD8, AUTS18, HELSNF1; chromodomain helicase DNA binding protein 8 (EC:3.6.4.12); K04494 chromodomain helicase DNA binding protein 8 [EC:3.6.4.12] (A)"	Wnt signaling pathway (ko04310)	[K]	Transcription	"SNF2 family N-terminal domain;; Chromo (CHRromatin Organisation MOdifier) domain;; BRK domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase"	Chromodomain-helicase-DNA-binding protein 8 GN=CHD8 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: chromodomain-helicase-DNA-binding protein 8 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000100889(PCK2)	--	25.42280968	998	22.47157502	937	17.8636891	728	9.426589593	379	9.916197952	388	19.49602928	792	2.00E-13	-1.423970783	down	1.36E-10	-1.29007449	down	0.970691322	0.113045338	normal	0.071400332	-0.79184696	normal	[C]	Energy production and conversion	Molecular Function: phosphoenolpyruvate carboxykinase activity (GO:0004611);; Biological Process: gluconeogenesis (GO:0006094);; 	"K01596|0|ggo:101146244|PCK2; phosphoenolpyruvate carboxykinase [GTP], mitochondrial; K01596 phosphoenolpyruvate carboxykinase (GTP) [EC:4.1.1.32] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; PPAR signaling pathway (ko03320);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Proximal tubule bicarbonate reclamation (ko04964)	[C]	Energy production and conversion	Phosphoenolpyruvate carboxykinase	"Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (Precursor) GN=PCK2 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: phosphoenolpyruvate carboxykinase [GTP], mitochondrial [Tupaia chinensis]"
ENSG00000100890(KIAA0391)	--	31.39798055	1196	28.91004477	1150	38.59159192	1184	32.78613139	1344	38.79378717	1411	27.83068691	1112	0.974796002	0.137317019	normal	0.932010997	0.273332593	normal	0.977508924	-0.098673661	normal	0.623093513	0.109907579	normal	--	--	--	K17655|0|pps:100988151|KIAA0391 ortholog; K17655 mitochondrial ribonuclease P protein 3 (A)	--	--	--	--	Mitochondrial ribonuclease P protein 3 (Precursor) GN=KIAA0391 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mitochondrial ribonuclease P protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000100897(DCAF11)	--	14.6620159	741	16.76906767	863	19.03320361	788	14.5520555	690	14.03407911	754	19.17592738	905	0.967142103	-0.133422662	normal	0.949117923	-0.215817623	normal	0.958020885	0.191088271	normal	0.87705965	-0.046607658	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11801|0|ptr:452808|DCAF11, WDR23; DDB1 and CUL4 associated factor 11; K11801 WD repeat-containing protein 23 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 11 GN=DCAF11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 11 isoform X8 [Tupaia chinensis]
ENSG00000100902(PSMA6)	--	178.4431479	2750	161.93053	2513	168.77126	2631	164.8513254	2577	158.1034584	2411	165.3261381	2564	0.985447323	-0.124499469	normal	0.986800808	-0.081155712	normal	0.988666329	-0.045479947	normal	0.713453307	-0.085111074	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: endopeptidase activity (GO:0004175);; Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Cellular Component: proteasome core complex, alpha-subunit complex (GO:0019773);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; "	"K02730|1.89237e-179|rno:29673|Psma6; proteasome (prosome, macropain) subunit, alpha type 6 (EC:3.4.25.1); K02730 20S proteasome subunit alpha 1 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome subunit A N-terminal signature	Proteasome subunit alpha type-6 GN=PSMA6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit alpha type-6 [Dasypus novemcinctus]
ENSG00000100906(NFKBIA)	--	55.17365108	1594	57.01941647	1667	48.39052857	1427	50.46334638	1463	42.18469701	1214	52.0345409	1512	0.97521939	-0.154398711	normal	0.452584066	-0.478401352	normal	0.982040807	0.075104031	normal	0.334674287	-0.183784353	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K04734|0|hsa:4792|NFKBIA, IKBA, MAD-3, NFKBI; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; K04734 NF-kappa-B inhibitor alpha (A)"	cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Adipocytokine signaling pathway (ko04920);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Shigellosis (ko05131);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222)	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies)	NF-kappa-B inhibitor alpha GN=NFKBIA OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: NF-kappa-B inhibitor alpha [Equus przewalskii]
ENSG00000100908(EMC9)	--	38.54628	488	27.98871	373	43.08253	573	31.35197	407	36.53451	457	29.27756	376	0.898838994	-0.291677367	normal	0.914412904	0.270599378	normal	0.088079538	-0.614078067	normal	0.488502372	-0.230455648	normal	--	--	--	--	--	[R]	General function prediction only	Uncharacterised protein family (UPF0172)	ER membrane protein complex subunit 9 GN=EMC9 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ER membrane protein complex subunit 9 [Felis catus] 
ENSG00000100911(PSME2)	--	54.9227332	1066	50.799022	978	56.0302229	1091	66.8138	1390	68.4408844	1277	44.16380087	883	0.840493271	0.351600305	normal	0.82224779	0.362933184	normal	0.888335024	-0.312974031	normal	0.658899107	0.157054268	normal	--	--	Cellular Component: proteasome activator complex (GO:0008537);; 	"K06697|5.86596e-152|hsa:5721|PSME2, PA28B, PA28beta, REGbeta; proteasome (prosome, macropain) activator subunit 2 (PA28 beta); K06697 proteasome activator subunit 2 (PA28 beta) (A)"	Proteasome (ko03050);; Antigen processing and presentation (ko04612)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome activator pa28 beta subunit;; Proteasome activator pa28 alpha subunit	Proteasome activator complex subunit 2 GN=PSME2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome activator complex subunit 2 [Felis catus]
ENSG00000100916(BRMS1L)	--	7.17803128	303	8.348210766	358	6.911141013	290	7.37489114	319	7.339701248	311	7.034061947	298	0.967177284	0.043192908	normal	0.937293256	-0.223457815	normal	0.967382342	0.030809492	normal	0.889495354	-0.056973562	normal	--	--	--	--	--	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	Sds3-like	Breast cancer metastasis-suppressor 1-like protein GN=BRMS1L OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: breast cancer metastasis-suppressor 1-like protein-like isoform 2 [Dasypus novemcinctus]
ENSG00000100918(REC8)	--	1.029308003	37	0.706269	31	0.992414015	28	1.01302063	35	1.407748	42	1.234905651	42	0.982397683	-0.106456524	normal	0.966999814	0.3998819	normal	0.950383618	0.552172187	normal	0.713453307	0.288957533	normal	--	--	Cellular Component: nuclear chromosome (GO:0000228);; Molecular Function: protein binding (GO:0005515);; 	"K13054|0|hsa:9985|REC8, HR21spB, REC8L1, Rec8p; REC8 meiotic recombination protein; K13054 meiotic recombination protein REC8, animal type (A)"	Oocyte meiosis (ko04114)	[D]	"Cell cycle control, cell division, chromosome partitioning"	N terminus of Rad21 / Rec8 like protein;; Conserved region of Rad21 / Rec8 like protein	Meiotic recombination protein REC8 homolog GN=REC8 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: meiotic recombination protein REC8 homolog [Pteropus alecto]
ENSG00000100926(TM9SF1)	--	88.23289942	2394	77.99794444	2174	86.12380052	2245	90.90869701	2399	92.5521173	2403	101.7926584	2752	0.988291608	-0.027804433	normal	0.983615059	0.12297676	normal	0.944783318	0.285299719	normal	0.5400727	0.128149814	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17085|0|pps:100972545|TM9SF1; transmembrane 9 superfamily member 1; K17085 transmembrane 9 superfamily member 1 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endomembrane protein 70	Transmembrane 9 superfamily member 1 (Precursor) GN=TM9SF1 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane 9 superfamily member 1 [Ursus maritimus] 
ENSG00000100934(SEC23A)	--	51.52463501	3247	47.41988701	2998	49.7090446	3093	58.85089103	3740	62.582751	3941	50.40325302	3180	0.983994127	0.173022293	normal	0.873274537	0.372970262	normal	0.990351852	0.031713197	normal	0.286545473	0.196380141	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: COPII vesicle coat (GO:0030127);; 	"K14006|0|hsa:10484|SEC23A, CLSD; Sec23 homolog A (S. cerevisiae); K14006 protein transport protein SEC23 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec23/Sec24 trunk domain;; Sec23/Sec24 helical domain;; Sec23/Sec24 beta-sandwich domain;; Sec23/Sec24 zinc finger;; Gelsolin repeat	Protein transport protein Sec23A GN=SEC23A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec23A [Ailuropoda melanoleuca] 
ENSG00000100938(GMPR2)	--	38.99251678	1130	36.99924796	1058	42.46945413	1048	35.29509817	1033	43.06475151	1197	46.47603081	1102	0.968905892	-0.160087015	normal	0.969881122	0.156446632	normal	0.978925222	0.064103849	normal	0.950033783	0.02117775	normal	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00364|0|mcf:102116300|GMPR2; guanosine monophosphate reductase 2; K00364 GMP reductase [EC:1.7.1.7] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	IMP dehydrogenase / GMP reductase domain;; FMN-dependent dehydrogenase	GMP reductase 2 GN=GMPR2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	GMP reductase 1 [Bos mutus]
ENSG00000100941(PNN)	--	46.30773	3333	49.91437362	3610	51.3182705	3631	44.35791031	3184	44.03863522	3147	41.91318484	3006	0.988911666	-0.096767598	normal	0.976365212	-0.219349707	normal	0.956013771	-0.280684678	normal	0.273112104	-0.200776767	normal	--	--	--	"K13114|0|hsa:5411|PNN, DRS, DRSP, SDK3, memA; pinin, desmosome associated protein; K13114 pinin (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[Z]	Cytoskeleton	pinin/SDK conserved region;; pinin/SDK/memA/ protein conserved region	Pinin GN=PNN OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: pinin isoform X3 [Vicugna pacos]
ENSG00000100949(RABGGTA)	--	5.920199	230	5.52045	221	6.907187	283	5.3876	212	6.07256	238	6.19875	237	0.957559042	-0.147376005	normal	0.962943506	0.08492856	normal	0.924317329	-0.262670488	normal	0.764023799	-0.115863298	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: Rab geranylgeranyltransferase activity (GO:0004663);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: protein prenyltransferase activity (GO:0008318);; Biological Process: protein prenylation (GO:0018342);; 	"K14050|0|hsa:5875|RABGGTA, PTAR3; Rab geranylgeranyltransferase, alpha subunit (EC:2.5.1.60); K14050 geranylgeranyl transferase type-2 subunit alpha [EC:2.5.1.60] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Protein prenyltransferase alpha subunit repeat;; Rab geranylgeranyl transferase alpha-subunit, insert domain;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat"	Geranylgeranyl transferase type-2 subunit alpha GN=RABGGTA OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: geranylgeranyl transferase type-2 subunit alpha [Vicugna pacos]
ENSG00000100968(NFATC4)	--	0.108913392	6	0.141118116	1	0.457031826	4	0.084882682	5	0.282512827	9	0.352334112	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K17334|0|hsa:4776|NFATC4, NF-AT3, NF-ATC4, NFAT3; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; K17334 nuclear factor of activated T-cells, cytoplasmic 4 (A)"	cGMP-PKG signaling pathway (ko04022);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; Oxytocin signaling pathway (ko04921);; Hepatitis B (ko05161);; HTLV-I infection (ko05166)	--	--	Rel homology domain (RHD);; IPT/TIG domain	"Nuclear factor of activated T-cells, cytoplasmic 4 GN=NFATC4 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: nuclear factor of activated T-cells, cytoplasmic 4 isoform X4 [Equus caballus]"
ENSG00000100979(PLTP)	--	1.700119	44	1.5291219	40	1.700768	45	0.596709	16	1.599296	42	1.336207	36	0.156853359	-1.405625591	normal	0.98003646	0.047220489	normal	0.971955626	-0.318238166	normal	0.472219628	-0.475475786	normal	--	--	Molecular Function: lipid binding (GO:0008289);; 	K08761|0|pps:100970161|PLTP; phospholipid transfer protein; K08761 phospholipid transfer protein (A)	PPAR signaling pathway (ko03320)	[V]	Defense mechanisms	"LBP / BPI / CETP family, C-terminal domain;; LBP / BPI / CETP family, N-terminal domain"	Phospholipid transfer protein (Precursor) GN=PLTP OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: phospholipid transfer protein isoform X2 [Galeopterus variegatus]
ENSG00000100982(PCIF1)	--	13.272104	703	15.021472	834	14.153304	786	11.424103	627	12.245961	664	12.29186	675	0.952760129	-0.19543889	normal	0.834164322	-0.349578564	normal	0.942985107	-0.227460509	normal	0.183459463	-0.261671807	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17584|0|ptr:458292|PCIF1; PDX1 C-terminal inhibiting factor 1; K17584 phosphorylated CTD-interacting factor 1 (A)	--	--	--	Phosphorylated CTD interacting factor 1 WW domain;; WW domain	Phosphorylated CTD-interacting factor 1 GN=PCIF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: phosphorylated CTD-interacting factor 1 [Ceratotherium simum simum]
ENSG00000100983(GSS)	--	42.70776427	1559	40.86110343	1523	41.98897865	1553	34.43072119	1264	28.75200279	1045	38.18428549	1397	0.875761061	-0.333091358	normal	0.137194908	-0.564158976	normal	0.973755226	-0.160852017	normal	0.032023581	-0.343658308	normal	--	--	Molecular Function: glutathione synthase activity (GO:0004363);; Molecular Function: ATP binding (GO:0005524);; Biological Process: glutathione biosynthetic process (GO:0006750);; 	"K01920|0|hsa:2937|GSS, GSHS, HEL-S-64p, HEL-S-88n; glutathione synthetase (EC:6.3.2.3); K01920 glutathione synthase [EC:6.3.2.3] (A)"	Glutathione metabolism (ko00480)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Eukaryotic glutathione synthase, ATP binding domain;; Eukaryotic glutathione synthase"	Glutathione synthetase GN=GSS OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: glutathione synthetase isoform X2 [Camelus bactrianus] 
ENSG00000100985(MMP9)	--	0	0	0	0	0.0236146	0	0	0	0.0476697	1	0.0242706	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K01403|0|hsa:4318|MMP9, CLG4B, GELB, MANDP2, MMP-9; matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35); K01403 matrix metalloproteinase-9 (gelatinase B) [EC:3.4.24.35] (A)"	TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Estrogen signaling pathway (ko04915);; Hepatitis B (ko05161);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Bladder cancer (ko05219)	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Fibronectin type II domain;; Hemopexin;; PT repeat;; Putative peptidoglycan binding domain	82 kDa matrix metalloproteinase-9 (Precursor) GN=MMP9 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: matrix metalloproteinase-9 isoform X1 [Oryctolagus cuniculus]
ENSG00000100987(VSX1)	--	1.039092847	49	1.103345333	48	0.944278276	40	0.721147197	33	0.838192395	37	0.946546736	38	0.930249467	-0.578881982	normal	0.96283835	-0.383146451	normal	0.981359244	-0.079218802	normal	0.59683371	-0.364212571	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09335|6.04287e-172|ptr:741063|VSX1; visual system homeobox 1; K09335 visual system homeobox protein 1 (A)	--	[R]	General function prediction only	Homeobox domain	Visual system homeobox 1 GN=VSX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: visual system homeobox 1 [Lipotes vexillifer]
ENSG00000100991(TRPC4AP)	--	43.7181	2723	40.9911	2566	42.3582	2643	45.1632	2800	46.7817	2891	44.2537	2751	0.989592914	0.009392355	normal	0.983235739	0.15053726	normal	0.988888244	0.049460532	normal	0.778577112	0.068694252	normal	--	--	--	"K11796|0|bacu:102998676|TRPC4AP; transient receptor potential cation channel, subfamily C, member 4 associated protein; K11796 Trpc4-associated protein (A)"	--	--	--	Protein of unknown function (DUF3689)	Short transient receptor potential channel 4-associated protein GN=TRPC4AP OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: short transient receptor potential channel 4-associated protein isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000100994(PYGB)	--	48.38479726	4118	48.227	4186	47.09603708	4080	62.17098718	5296	61.33270791	5184	51.02420001	4351	0.935489698	0.332017556	normal	0.963383605	0.286973534	normal	0.991270372	0.084456105	normal	0.180085465	0.238371374	normal	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: glycogen phosphorylase activity (GO:0008184);; 	"K00688|0|hsa:5834|PYGB, GPBB; phosphorylase, glycogen; brain (EC:2.4.1.1); K00688 starch phosphorylase [EC:2.4.1.1] (A)"	Starch and sucrose metabolism (ko00500);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Carbohydrate phosphorylase	"Glycogen phosphorylase, brain form GN=PYGB OS=Homo sapiens (Human) PE=1 SV=5"	G	Carbohydrate transport and metabolism	"PREDICTED: glycogen phosphorylase, brain form [Ceratotherium simum simum]"
ENSG00000100997(ABHD12)	--	71.173497	2534	75.67732872	2714	70.98437508	2601	71.0689477	2542	70.10493716	2471	82.72187121	2960	0.98879037	-0.026268855	normal	0.981999438	-0.15666074	normal	0.980460665	0.178142181	normal	0.999953667	0.001827146	normal	[R]	General function prediction only	--	K13704|0|ptr:744997|ABHD12; abhydrolase domain containing 12; K13704 abhydrolase domain-containing protein 12 [EC:3.1.1.23] (A)	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; alpha/beta hydrolase fold	Monoacylglycerol lipase ABHD12 GN=ABHD12 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: monoacylglycerol lipase ABHD12 [Oryctolagus cuniculus]
ENSG00000101000(PROCR)	--	109.51052	2192	102.5780865	2120	124.19795	2512	54.10443385	1114	65.4318713	1219	46.20614387	968	2.58E-07	-1.00632124	down	0.000229785	-0.819011861	normal	1.85E-14	-1.382656134	down	1.38E-15	-1.068937272	down	--	--	--	"K06557|3.47873e-167|hsa:10544|PROCR, CCCA, CCD41, EPCR; protein C receptor, endothelial; K06557 protein C receptor, endothelial (EPCR) (A)"	--	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2"	Endothelial protein C receptor (Precursor) GN=PROCR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endothelial protein C receptor [Oryctolagus cuniculus]
ENSG00000101003(GINS1)	--	24.94185	1187	25.41502	1212	27.10541	1270	31.34482	1497	28.08874	1330	22.78452	1080	0.908086024	0.303571491	normal	0.977182098	0.112475986	normal	0.946415809	-0.241776062	normal	0.798499626	0.068625833	normal	[S]	Function unknown	--	K10732|2.1958e-144|ptr:458147|GINS1; GINS complex subunit 1 (Psf1 homolog); K10732 GINS complex subunit 1 (A)	--	[L]	"Replication, recombination and repair"	--	DNA replication complex GINS protein PSF1 GN=GINS1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA replication complex GINS protein PSF1 [Odobenus rosmarus divergens] 
ENSG00000101004(NINL)	--	8.6553218	1036	9.800103021	1208	7.980353	998	7.434938	894	9.728676	1112	8.739844307	1065	0.941013273	-0.243120942	normal	0.972709209	-0.140706561	normal	0.977157226	0.085325088	normal	0.681330319	-0.099024159	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K16477|0|hsa:22981|NINL, NLP, dJ691N24.1; ninein-like; K16477 ninein-like protein (A)"	--	--	--	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair	Ninein-like protein GN=NINL OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: ninein-like protein [Tupaia chinensis]
ENSG00000101017(CD40)	--	2.114896642	65	1.886071123	61	1.661755589	54	2.94702218	94	3.7627531	119	2.252487523	72	0.879941397	0.49167784	normal	0.079154637	0.925935587	normal	0.942891579	0.397085049	normal	0.136419042	0.64100693	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03160|0|hsa:958|CD40, Bp50, CDW40, TNFRSF5, p50; CD40 molecule, TNF receptor superfamily member 5; K03160 tumor necrosis factor receptor superfamily member 5 (A)"	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Cell adhesion molecules (CAMs) (ko04514);; Toll-like receptor signaling pathway (ko04620);; Intestinal immune network for IgA production (ko04672);; Malaria (ko05144);; Toxoplasmosis (ko05145);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Transcriptional misregulation in cancer (ko05202);; Asthma (ko05310);; Autoimmune thyroid disease (ko05320);; Systemic lupus erythematosus (ko05322);; Allograft rejection (ko05330);; Primary immunodeficiency (ko05340);; Viral myocarditis (ko05416)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 5 (Precursor) GN=CD40 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 5 isoform X2 [Galeopterus variegatus]
ENSG00000101019(UQCC1)	--	19.75928156	853	17.66169416	805	20.08431004	880	23.03865115	866	18.54554866	836	16.81215912	789	0.977752014	-0.008994901	normal	0.976292794	0.033026718	normal	0.963896354	-0.165469191	normal	0.870465374	-0.048310101	normal	--	--	--	K17662|0|pps:100983071|ubiquinol-cytochrome-c reductase complex assembly factor 1; K17662 cytochrome b pre-mRNA-processing protein 3 (A)	--	[C]	Energy production and conversion	Ubiquinol-cytochrome C chaperone	Ubiquinol-cytochrome-c reductase complex assembly factor 1 GN=UQCC1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	ubiquinol-cytochrome c reductase complex chaperone CBP3 homolog [Sus scrofa] 
ENSG00000101040(ZMYND8)	--	8.258838047	807	6.01883654	705	5.922335675	692	8.927393	1079	12.66649986	1474	10.55495098	1243	0.752380835	0.387581959	normal	2.76E-07	1.041036729	up	0.000176556	0.83530976	normal	0.00021914	0.763563492	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Domain of unknown function (DUF3544);; Bromodomain;; PWWP domain;; PHD-finger;; MYND finger	Protein kinase C-binding protein 1 GN=ZMYND8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein kinase C-binding protein 1 isoform X1 [Loxodonta africana] 
ENSG00000101049(SGK2)	--	3.566172066	140	1.8914086	101	2.968683913	145	6.71554452	348	6.894904324	339	6.1169374	266	1.73E-07	1.273671943	up	1.69E-12	1.710689058	up	0.007055601	0.860358277	normal	1.93E-08	1.282356457	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K13303|0|hsa:10110|SGK2, H-SGK2, dJ138B7.2; serum/glucocorticoid regulated kinase 2 (EC:2.7.11.1); K13303 serum/glucocorticoid-regulated kinase 2 [EC:2.7.11.1] (A)"	FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151)	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Protein kinase C terminal domain	Serine/threonine-protein kinase Sgk2 GN=SGK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Sgk2 isoform X1 [Equus caballus]
ENSG00000101052(IFT52)	--	18.144	569	17.61733	546	16.64033	510	19.00297	589	18.18284	558	16.15628	501	0.973109251	0.018956409	normal	0.972068682	0.009910461	normal	0.971447111	-0.033876732	normal	1	-0.001533839	normal	--	--	--	--	--	[W]	Extracellular structures	ABC-type uncharacterized transport system	Intraflagellar transport protein 52 homolog GN=IFT52 OS=Homo sapiens (Human) PE=2 SV=3	W	Extracellular structures	PREDICTED: intraflagellar transport protein 52 homolog isoform 1 [Tursiops truncatus]
ENSG00000101057(MYBL2)	--	34.66203401	2234	38.464073	2473	38.333556	2485	45.11417773	2890	43.14607189	2738	36.63863763	2345	0.896495655	0.340401738	normal	0.984861792	0.125360772	normal	0.986435946	-0.091891794	normal	0.541490103	0.127018173	normal	[KAD]	"Transcription;; RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	--	K09421|0|pps:100971749|MYBL2; v-myb avian myeloblastosis viral oncogene homolog-like 2; K09421 myb-related protein (A)	HTLV-I infection (ko05166)	--	--	"C-myb, C-terminal;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain"	Myb-related protein B GN=MYBL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myb-related protein B [Galeopterus variegatus]
ENSG00000101074(R3HDML)	--	0	0	0	0	0	0	0.293587823	9	1.116247	38	0.090667714	4	--	--	--	7.43E-08	4.697231066	up	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family	Peptidase inhibitor R3HDML (Precursor) GN=R3HDML OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: peptidase inhibitor R3HDML [Physeter catodon]
ENSG00000101076(HNF4A)	--	0.77101038	69	1.063569966	101	0.514586398	50	5.6273464	496	9.058747084	687	5.1548545	434	0	2.787911998	up	0	2.726440547	up	0	3.071569552	up	3.35E-11	2.855467783	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K07292|0|hsa:3172|HNF4A, FRTS4, HNF4, HNF4a7, HNF4a8, HNF4a9, HNF4alpha, MODY, MODY1, NR2A1, NR2A21, TCF, TCF14; hepatocyte nuclear factor 4, alpha; K07292 hepatocyte nuclear factor 4-alpha (A)"	AMPK signaling pathway (ko04152);; Maturity onset diabetes of the young (ko04950)	[K]	Transcription	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Hepatocyte nuclear factor 4-alpha GN=HNF4A OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: hepatocyte nuclear factor 4-alpha isoform 1 [Orcinus orca]
ENSG00000101079(NDRG3)	--	21.4142088	1118	17.787933	926	19.54232404	989	19.58836087	1020	17.922517	931	16.54153803	872	0.968196837	-0.162948735	normal	0.978136542	-0.013635375	normal	0.960043942	-0.18962481	normal	0.580062213	-0.125208081	normal	--	--	--	--	--	[S]	Function unknown	Ndr family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold	Protein NDRG3 GN=NDRG3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein NDRG3 isoform X1 [Mustela putorius furo]
ENSG00000101082(SLA2)	--	0.215683	12	0.249567	14	0.157856	8	0.252587	14	0.280785	15	0.213804	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SH2 domain;; SH3 domain	Src-like-adapter 2 GN=SLA2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: src-like-adapter 2 [Equus caballus] 
ENSG00000101084(C20orf24)	--	115.5046979	1986	126.8679302	2169	129.4395841	2225	157.6057519	2687	153.4470855	2593	156.1037573	2560	0.758237691	0.40502817	normal	0.965468817	0.236014929	normal	0.975698262	0.19392406	normal	0.097071099	0.276064421	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab5-interacting protein (Rab5ip)	Uncharacterized protein C20orf24 GN=C20orf24 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: uncharacterized protein C20orf24 homolog isoform 2 [Canis lupus familiaris]
ENSG00000101096(NFATC2)	--	0.62309023	89	0.76113258	102	0.611277135	80	0.396614819	54	0.594564236	76	0.286157282	34	0.581423163	-0.735207678	normal	0.893456408	-0.43836612	normal	0.029504836	-1.206737226	normal	0.079815391	-0.746945621	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K17332|0|ggo:101131247|NFATC2; nuclear factor of activated T-cells, cytoplasmic 2 isoform 1; K17332 nuclear factor of activated T-cells, cytoplasmic 2 (A)"	cGMP-PKG signaling pathway (ko04022);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Oxytocin signaling pathway (ko04921);; Hepatitis B (ko05161);; HTLV-I infection (ko05166)	--	--	Rel homology domain (RHD);; IPT/TIG domain	"Nuclear factor of activated T-cells, cytoplasmic 2 GN=NFATC2 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: nuclear factor of activated T-cells, cytoplasmic 2 isoform X1 [Galeopterus variegatus]"
ENSG00000101098(RIMS4)	--	1.82081	193	1.4407381	150	1.263655	135	0.608244262	64	0.760328382	78	0.58399762	62	2.61E-08	-1.600019765	down	0.020269586	-0.951300925	normal	0.003847836	-1.112069969	down	6.14E-05	-1.249959394	down	--	--	--	"K15299|0|hsa:140730|RIMS4, C20orf190, RIM_4, RIM-4, RIM4, RIM4-gamma, RIM4gamma; regulating synaptic membrane exocytosis 4; K15299 regulating synaptic membrane exocytosis protein 4 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Regulating synaptic membrane exocytosis protein 4 GN=RIMS4 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: regulating synaptic membrane exocytosis protein 4 [Orcinus orca] 
ENSG00000101104(PABPC1L)	--	17.8093452	494	17.79833759	518	15.98451856	499	8.189848269	269	8.888544584	258	12.8560767	406	0.000251014	-0.903865041	normal	1.34E-05	-1.022687959	down	0.887753803	-0.304825457	normal	0.000453019	-0.715555852	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	"K13126|0|hsa:80336|PABPC1L, C20orf119, PABPC1L1, dJ1069P2.3, ePAB; poly(A) binding protein, cytoplasmic 1-like; K13126 polyadenylate-binding protein (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; RNA degradation (ko03018)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Poly-adenylate binding protein, unique domain;; Limkain b1"	Polyadenylate-binding protein 1-like GN=PABPC1L OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: polyadenylate-binding protein 1-like isoform X1 [Galeopterus variegatus]
ENSG00000101109(STK4)	--	13.47198262	1574	12.83222878	1501	12.80081967	1479	12.1639135	1420	11.1951035	1294	11.64622824	1357	0.970682389	-0.179192605	normal	0.953490482	-0.235257359	normal	0.977035891	-0.132351442	normal	0.338106672	-0.183171037	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04411|0|hsa:6789|STK4, KRS2, MST1, TIIAC, YSK3; serine/threonine kinase 4 (EC:2.7.11.1); K04411 serine/threonine kinase 4 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; FoxO signaling pathway (ko04068);; Pathways in cancer (ko05200);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; C terminal SARAH domain of Mst1	Serine/threonine-protein kinase 4 18kDa subunit GN=STK4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 4 isoform X2 [Ochotona princeps]
ENSG00000101115(SALL4)	--	1.79935159	288	1.236347325	236	1.148984	227	1.241312317	269	1.8972293	393	1.611567111	327	0.959860785	-0.128584894	normal	0.034949039	0.710750799	normal	0.482530693	0.515430666	normal	0.201199975	0.376447282	normal	[R]	General function prediction only	--	--	--	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Sal-like protein 4 GN=SALL4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: sal-like protein 4 isoform X2 [Equus przewalskii]
ENSG00000101126(ADNP)	--	28.44829268	2679	29.4889503	2656	27.27745185	2442	25.9009934	2538	29.57486374	2963	27.2101842	2511	0.986271907	-0.108770672	normal	0.984830229	0.136303418	normal	0.988509196	0.031887911	normal	0.943924155	0.021661137	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	Homeobox domain	Activity-dependent neuroprotector homeobox protein GN=ADNP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: activity-dependent neuroprotector homeobox protein [Galeopterus variegatus] 
ENSG00000101132(PFDN4)	--	30.023854	563	28.93926929	543	27.732752	510	24.97780692	482	24.46621073	461	21.729536	410	0.924990891	-0.254183397	normal	0.923259925	-0.256834685	normal	0.869771227	-0.322097337	normal	0.207699757	-0.278056311	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein folding (GO:0006457);; Cellular Component: prefoldin complex (GO:0016272);; Molecular Function: unfolded protein binding (GO:0051082);; 	K09550|1.29209e-73|oas:101112255|prefoldin subunit 4-like; K09550 prefoldin subunit 4 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prefoldin subunit	Prefoldin subunit 4 GN=PFDN4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prefoldin subunit 4-like [Ceratotherium simum simum]
ENSG00000101134(DOK5)	--	0.039595077	1	0.060267826	2	0.059748256	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	--	--	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type);; PH domain	Docking protein 5 GN=DOK5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: docking protein 5 isoform X1 [Oryctolagus cuniculus]
ENSG00000101138(CSTF1)	--	17.414921	698	17.486388	714	16.907008	705	18.506981	669	16.762483	721	15.85641437	659	0.97135878	-0.091846552	normal	0.975106369	-0.007335911	normal	0.970142321	-0.105402328	normal	0.812748011	-0.06829635	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K14406|0|ptr:100610308|CSTF1; cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa; K14406 cleavage stimulation factor subunit 1 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"WD domain, G-beta repeat"	Cleavage stimulation factor subunit 1 GN=CSTF1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: cleavage stimulation factor subunit 1 [Odobenus rosmarus divergens]
ENSG00000101144(BMP7)	--	0.835222551	44	0.412293272	28	0.335961873	23	0.099828801	3	0.096606632	2	0.06551898	2	8.23E-07	-3.352477897	down	0.001069547	-3.087104043	down	0.019859477	-2.809273621	normal	1.01E-06	-3.78573061	down	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K16621|0|ptr:458357|BMP7; bone morphogenetic protein 7; K16621 bone morphogenetic protein 7 (A)	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Bone morphogenetic protein 7 (Precursor) GN=BMP7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein 7 [Tupaia chinensis]
ENSG00000101146(RAE1)	--	26.39698538	930	23.98380925	837	21.78372235	834	24.40911377	900	25.81825081	937	21.03616156	794	0.976075266	-0.078006962	normal	0.968601436	0.141153735	normal	0.974630397	-0.079052888	normal	0.991625578	-0.00503765	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14298|0|pps:100980561|RAE1; ribonucleic acid export 1; K14298 mRNA export factor (A)	RNA transport (ko03013);; Influenza A (ko05164)	[A]	RNA processing and modification	"WD domain, G-beta repeat"	mRNA export factor GN=RAE1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: mRNA export factor isoform X1 [Capra hircus]
ENSG00000101150(TPD52L2)	--	53.85846661	2199	51.25648	2113	56.304333	2325	80.40054768	3306	69.42299018	2834	60.99900001	2515	0.152885733	0.557087441	normal	0.784836775	0.401871282	normal	0.985740959	0.104970579	normal	0.02583711	0.361111648	normal	--	--	--	--	--	[R]	General function prediction only	Tumour protein D52 family	Tumor protein D54 GN=TPD52L2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: tumor protein D54 isoform X3 [Equus caballus]
ENSG00000101152(DNAJC5)	--	22.24996	2157	21.42459	2127	21.90276	2167	25.69697	2489	24.72241	2380	25.06551	2423	0.978275804	0.175591288	normal	0.981899664	0.14062043	normal	0.981131719	0.152702982	normal	0.427630066	0.155532378	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09525|8.31041e-122|hgl:101700492|Dnajc5; DnaJ (Hsp40) homolog, subfamily C, member 5; K09525 DnaJ homolog subfamily C member 5 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 5 GN=DNAJC5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 5 isoform X1 [Galeopterus variegatus]
ENSG00000101158(NELFCD)	--	20.0391	917	24.7298	1140	21.2064	975	21.769	995	22.7272	1031	25.8038	1180	0.975998801	0.08680289	normal	0.967563647	-0.166184112	normal	0.930733452	0.266644815	normal	0.82445739	0.059681616	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	"K15181|0|hsa:51497|NELFCD, NELF-C, NELF-D, TH1, TH1L; negative elongation factor complex member C/D; K15181 negative elongation factor C/D (A)"	--	--	--	TH1 protein	Negative elongation factor C/D GN=NELFCD OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: negative elongation factor D-like [Odobenus rosmarus divergens]
ENSG00000101160(CTSZ)	--	115.643	3320	120.712	3593	112.553	3347	100.774	2953	99.8064	2843	108.35	3126	0.978886005	-0.199736063	normal	0.889384776	-0.359031077	normal	0.988364417	-0.106792275	normal	0.209782503	-0.222705447	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	K08568|0|ptr:736240|CTSZ; cathepsin Z; K08568 cathepsin X [EC:3.4.18.1] (A)	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease	Cathepsin Z (Precursor) GN=CTSZ OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin Z [Ceratotherium simum simum]
ENSG00000101161(PRPF6)	--	24.46001	1847	23.55689	1804	25.55451	1962	24.58911	1862	25.35887	1898	23.02743	1742	0.986069653	-0.019147194	normal	0.98505307	0.05181175	normal	0.974165283	-0.179724748	normal	0.847174874	-0.05003898	normal	[R]	General function prediction only	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; "	K12855|0|pps:100980821|PRPF6; pre-mRNA processing factor 6; K12855 pre-mRNA-processing factor 6 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"PRP1 splicing factor, N-terminal;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Suppressor of forked protein (Suf);; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Pre-mRNA-processing factor 6 GN=PRPF6 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pre-mRNA-processing factor 6 isoform 1 [Trichechus manatus latirostris]
ENSG00000101162(TUBB1)	--	0.168989	11	0.122451	8	0.0302567	1	0.199134	13	0.193592	12	0.182536	12	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07375|0|hsa:81027|TUBB1; tubulin, beta 1 class VI; K07375 tubulin beta (A)"	Phagosome (ko04145);; Gap junction (ko04540);; Pathogenic Escherichia coli infection (ko05130)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta-1 chain GN=TUBB1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin beta-1 chain isoform X1 [Oryctolagus cuniculus]
ENSG00000101166(PRELID3B)	--	42.52695	1564	47.28733	1733	41.70965	1480	37.0471	1379	34.28968	1267	32.75537	1189	0.962315043	-0.212228093	normal	0.479281208	-0.472797011	normal	0.886103833	-0.323770025	normal	0.035169427	-0.338735343	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PRELI-like family	Protein slowmo homolog 2 GN=SLMO2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein slowmo homolog 2 [Ailuropoda melanoleuca]
ENSG00000101181(MTG2)	--	10.530051	530	9.532273098	536	10.31888598	606	9.493401333	541	10.75270012	761	11.27382133	688	0.972433884	-0.001192607	normal	0.44732367	0.48308768	normal	0.958171466	0.174390643	normal	0.371323019	0.231028012	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K03979|0|hsa:26164|MTG2, GTPBP5, ObgH1, dJ1005F21.2; mitochondrial ribosome-associated GTPase 2; K03979 GTP-binding protein (A)"	--	[R]	General function prediction only	GTP1/OBG;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B;; ADP-ribosylation factor family	Mitochondrial ribosome-associated GTPase 2 GN=MTG2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: mitochondrial ribosome-associated GTPase 2 [Galeopterus variegatus]
ENSG00000101182(PSMA7)	--	200.1500134	3095	205.2740876	3286	205.4641166	3301	236.3581436	3765	235.4602834	3628	225.6281533	3521	0.968240959	0.251764734	normal	0.987901372	0.121362248	normal	0.989729268	0.084753046	normal	0.450305234	0.151460234	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: endopeptidase activity (GO:0004175);; Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Cellular Component: proteasome core complex, alpha-subunit complex (GO:0019773);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; "	"K02731|5.17274e-163|hsa:5688|PSMA7, C6, HSPC, RC6-1, XAPC7; proteasome (prosome, macropain) subunit, alpha type, 7 (EC:3.4.25.1); K02731 20S proteasome subunit alpha 4 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome subunit A N-terminal signature	Proteasome subunit alpha type-7 GN=PSMA7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	proteasome subunit alpha type-7 [Bos taurus] 
ENSG00000101187(SLCO4A1)	--	9.158207387	406	6.916461501	319	9.58700508	452	6.366363	290	3.928368	180	5.701532297	267	0.419997953	-0.513945688	normal	0.005455511	-0.841599197	normal	0.007838905	-0.764407797	normal	0.016356831	-0.696593202	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14354|0|hsa:28231|SLCO4A1, OATP-E, OATP1, OATP4A1, OATPE, OATPRP1, POAT, SLC21A12; solute carrier organic anion transporter family, member 4A1; K14354 solute carrier organic anion transporter family, member 4A (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain	Solute carrier organic anion transporter family member 4A1 GN=SLCO4A1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 4A1 isoform X2 [Equus przewalskii]
ENSG00000101188(NTSR1)	--	0.298786	24	0.0369593	3	0.107938	8	0.0125513	1	0.0120576	0	0	0	0.002096736	-3.352256572	down	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04211|0|hsa:4923|NTSR1, NTR; neurotensin receptor 1 (high affinity); K04211 neurotensin receptor 1 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv	Neurotensin receptor type 1 GN=NTSR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neurotensin receptor type 1 [Bos mutus]
ENSG00000101189(MRGBP)	--	12.56854835	705	10.81340058	611	13.02935843	739	9.538986345	537	8.845450807	497	8.359494798	475	0.653621818	-0.422474736	normal	0.87398063	-0.318477328	normal	0.037787889	-0.644280076	normal	0.00953523	-0.466875299	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Cellular Component: H4/H2A histone acetyltransferase complex (GO:0043189);; "	K11343|5.66695e-95|mcf:102116983|MRGBP; MRG/MORF4L binding protein; K11343 MRG-binding protein (A)	--	[S]	Function unknown	Chromatin modification-related protein EAF7	MRG/MORF4L-binding protein GN=MRGBP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MRG/MORF4L-binding protein isoform X1 [Loxodonta africana]
ENSG00000101190(TCFL5)	--	9.235069	386	8.49747	365	7.788031	335	8.527458	365	9.85453	413	8.231911	349	0.963306339	-0.111081855	normal	0.955937791	0.156210033	normal	0.967512512	0.050550911	normal	0.940283296	0.032034865	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09092|0|ptr:458455|TCFL5; transcription factor-like 5 (basic helix-loop-helix); K09092 transcription factor-like 5 (A)	--	--	--	Helix-loop-helix DNA-binding domain	Transcription factor-like 5 protein GN=TCFL5 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: transcription factor-like 5 protein [Sarcophilus harrisii]
ENSG00000101191(DIDO1)	--	14.96903168	2659	14.28039525	2489	13.82765302	2493	15.51098754	2682	16.13890591	2846	14.77283727	2645	0.989278506	-0.01839622	normal	0.980551336	0.171845175	normal	0.987653592	0.077048017	normal	0.748610372	0.075868644	normal	--	--	"Biological Process: transcription, DNA-templated (GO:0006351);; "	--	--	[R]	General function prediction only	"Transcription factor S-II (TFIIS), central domain;; SPOC domain;; PHD-finger"	Death-inducer obliterator 1 GN=DIDO1 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: death-inducer obliterator 1 [Galeopterus variegatus]
ENSG00000101193(GID8)	--	14.01389	1005	13.93259	1022	13.18321	962	13.73733	1019	14.561124	1062	15.12019	1091	0.97964402	-0.01085723	normal	0.97914986	0.033912784	normal	0.965641902	0.172995339	normal	0.806299171	0.064660571	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	CTLH/CRA C-terminal to LisH motif domain;; LisH	Glucose-induced degradation protein 8 homolog GN=GID8 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: glucose-induced degradation protein 8 homolog isoformX1 [Canis lupus familiaris] 
ENSG00000101197(BIRC7)	--	2.231149492	106	2.623666966	109	2.363370642	133	3.587426	151	4.401651058	213	4.216274	219	0.804529622	0.473871441	normal	0.005641977	0.935649061	normal	0.135267699	0.704904676	normal	0.014418954	0.72475247	normal	--	--	--	K16061|0|ggo:101134711|BIRC7; baculoviral IAP repeat-containing protein 7 isoform 1; K16061 baculoviral IAP repeat-containing protein 7/8 (A)	Ubiquitin mediated proteolysis (ko04120);; Apoptosis (ko04210);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	"Inhibitor of Apoptosis domain;; Zinc finger, C3HC4 type (RING finger);; Prokaryotic RING finger family 4"	Baculoviral IAP repeat-containing protein 7 30kDa subunit GN=UNQ5800/PRO19607/PRO21344 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: baculoviral IAP repeat-containing protein 7 [Galeopterus variegatus]
ENSG00000101198(NKAIN4)	--	2.75962	60	4.786814	107	3.872862005	85	6.073268	133	9.663735	206	6.134247127	135	0.005666521	1.098212328	up	0.009229265	0.914139157	normal	0.508136661	0.649880801	normal	0.039985393	0.890458733	normal	--	--	--	--	--	[S]	Function unknown	"Na,K-Atpase Interacting protein"	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 GN=NKAIN4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4 [Ceratotherium simum simum]
ENSG00000101199(ARFGAP1)	--	29.55104088	2078	29.21521565	2109	31.55825683	2118	43.6708746	2794	46.66630641	3016	37.21711495	2622	0.787173954	0.396050777	normal	0.425976621	0.494352904	normal	0.933433517	0.299481122	normal	0.008577615	0.398079243	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; 	K12492|0|ggo:101135654|ARFGAP1; ADP-ribosylation factor GTPase-activating protein 1 isoform 1; K12492 ADP-ribosylation factor GTPase-activating protein 1 (A)	Endocytosis (ko04144)	[TUZ]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	Putative GTPase activating protein for Arf	ADP-ribosylation factor GTPase-activating protein 1 GN=ARFGAP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ADP-ribosylation factor GTPase-activating protein 1 isoform X1 [Erinaceus europaeus]
ENSG00000101203(COL20A1)	--	0.395982074	24	0.097306791	18	0.10558798	14	0.088544085	5	0.11407042	8	0.415964733	22	0.234264875	-1.992259232	normal	--	--	--	0.978466615	0.592382825	normal	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	Fibronectin type III domain;; von Willebrand factor type A domain;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain	Collagen alpha-1(XX) chain (Precursor) GN=COL20A1 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: collagen alpha-1(XX) chain [Ceratotherium simum simum]
ENSG00000101204(CHRNA4)	--	0.027305215	3	0	0	0.00870193	0	0.009144752	1	0.026519235	2	0.026996256	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04806|0|hsa:1137|CHRNA4, BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4; cholinergic receptor, nicotinic, alpha 4 (neuronal); K04806 nicotinic acetylcholine receptor alpha-4 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Neuronal acetylcholine receptor subunit alpha-4 (Precursor) GN=CHRNA4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuronal acetylcholine receptor subunit alpha-4 isoform X1 [Galeopterus variegatus]
ENSG00000101210(EEF1A2)	--	137.0758	5261	106.1081	4130	108.9027	4270	199.1463	7660	228.98152	8725	125.444719	4818	0.438250971	0.511050746	normal	3.83E-08	1.05731443	up	0.987465127	0.165851554	normal	0.142041222	0.611851663	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K03231|0|ocu:100008677|EEF1A2, EEF1A-2; eukaryotic translation elongation factor 1 alpha 2; K03231 elongation factor 1-alpha (A)"	RNA transport (ko03013);; Legionellosis (ko05134)	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2	Elongation factor 1-alpha 2 GN=EEF1A2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	"Elongation factor 1-alpha 2, partial [Bos mutus]"
ENSG00000101213(PTK6)	--	1.4927661	83	0.826932456	48	1.376196	72	2.329427	121	1.717729	93	2.019666	107	0.818464903	0.505206597	normal	0.212959397	0.911787371	normal	0.792216912	0.553652711	normal	0.116050235	0.639691945	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08894|0|ggo:101141155|PTK6; protein-tyrosine kinase 6 isoform 1; K08894 protein tyrosine kinase 6 [EC:2.7.10.2] (A)	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Protein-tyrosine kinase 6 GN=PTK6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein-tyrosine kinase 6 [Galeopterus variegatus]
ENSG00000101216(GMEB2)	--	4.783051841	403	4.79374686	396	4.40592091	380	4.888676859	408	5.4103712	445	4.926544622	417	0.96973169	-0.012993717	normal	0.958342983	0.146350903	normal	0.962070992	0.125280429	normal	0.793355372	0.086098319	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	SAND domain	Glucocorticoid modulatory element-binding protein 2 GN=GMEB2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: glucocorticoid modulatory element-binding protein 2 [Oryctolagus cuniculus]
ENSG00000101220(C20orf27)	--	61.173638	1426	58.14976122	1426	59.51163512	1510	65.31094894	1532	64.003959	1474	56.099149	1307	0.982197431	0.072534646	normal	0.983081327	0.026308543	normal	0.960248688	-0.216347738	normal	0.89361351	-0.037838637	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4517)	UPF0687 protein C20orf27 GN=C20orf27 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: UPF0687 protein C20orf27 homolog isoform X1 [Camelus ferus]
ENSG00000101222(SPEF1)	--	0.873189	24	0.453733	13	0.681403	19	0.716646	20	0.70339	19	0.930939	26	0.985820188	-0.274582274	normal	--	--	--	0.98095216	0.415829789	normal	--	--	--	--	--	--	--	--	--	--	Domain of Unknown Function (DUF1042);; CAMSAP CH domain;; Calponin homology (CH) domain	Sperm flagellar protein 1 GN=SPEF1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: sperm flagellar protein 1 [Galeopterus variegatus]
ENSG00000101224(CDC25B)	--	180.9327261	10502	156.163748	9071	167.653593	9720	87.396161	5069	88.99591759	5158	140.85566	8157	6.38E-09	-1.081490192	down	0.000144857	-0.835689039	normal	0.982729171	-0.261164688	normal	0.00475676	-0.691850387	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Cellular Component: intracellular (GO:0005622);; Biological Process: protein dephosphorylation (GO:0006470);; Biological Process: positive regulation of cell cycle G2/M phase transition (GO:1902751);; 	K05866|0|ggo:101127265|CDC25B; M-phase inducer phosphatase 2 isoform 1; K05866 M-phase inducer phosphatase 2 [EC:3.1.3.48] (A)	MAPK signaling pathway (ko04010);; Cell cycle (ko04110);; Progesterone-mediated oocyte maturation (ko04914);; MicroRNAs in cancer (ko05206)	[D]	"Cell cycle control, cell division, chromosome partitioning"	M-phase inducer phosphatase;; Rhodanese-like domain	M-phase inducer phosphatase 2 GN=CDC25B OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: M-phase inducer phosphatase 2 isoform 1 [Ceratotherium simum simum]
ENSG00000101230(ISM1)	--	0.0375073	2	0.0743352	4	0	0	0.0373936	2	0.0908902	4	0.0926976	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	AMOP domain;; Thrombospondin type 1 domain	Isthmin-1 (Precursor) GN=ISM1 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: isthmin-1 [Leptonychotes weddellii]
ENSG00000101236(RNF24)	--	11.808946	1126	9.54394	1108	10.279781	1054	9.696411	1017	9.678885	933	9.455275	991	0.965291316	-0.17746446	normal	0.928440264	-0.269034725	normal	0.976149703	-0.097065691	normal	0.360992033	-0.182304591	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 24 GN=RNF24 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 24 [Equus przewalskii]
ENSG00000101246(ARFRP1)	--	15.0968083	469	14.4283298	441	16.214682	501	18.0685816	539	17.9311807	518	17.3965201	520	0.956122939	0.169347302	normal	0.943650942	0.210081595	normal	0.971142508	0.045275427	normal	0.605168372	0.139346306	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07952|6.05035e-148|pps:100976524|ARFRP1; ADP-ribosylation factor related protein 1; K07952 ADP-ribosylation factor related protein 1 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Miro-like protein;; Signal recognition particle receptor beta subunit;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase	ADP-ribosylation factor-related protein 1 GN=ARFRP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-related protein 1 [Felis catus] 
ENSG00000101247(NDUFAF5)	--	14.533872	321	14.6362158	314	15.94008062	345	17.28337642	394	13.784593	367	13.85790589	344	0.919440275	0.263649471	normal	0.944127807	0.202685287	normal	0.968618706	-0.012424697	normal	0.620321721	0.151745768	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K18162|0|ptr:458103|NDUFAF5; NADH dehydrogenase (ubiquinone) complex I, assembly factor 5; K18162 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 [EC:2.1.1.-] (A)"	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; Putative S-adenosyl-L-methionine-dependent methyltransferase	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 (Precursor) GN=NDUFAF5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 5 isoform X2 [Canis lupus familiaris]
ENSG00000101255(TRIB3)	--	42.55574	1714	47.4958622	2016	37.63607104	1550	36.26683009	1526	31.09537313	1312	126.4705948	5503	0.967938828	-0.198255921	normal	0.02783962	-0.640553956	normal	0	1.818653358	up	0.702729366	0.642112494	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08814|0|mcf:102127598|TRIB3; tribbles homolog 3 (Drosophila); K08814 tribbles [EC:2.7.11.-] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Tribbles homolog 3 GN=TRIB3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: tribbles homolog 3 [Trichechus manatus latirostris]
ENSG00000101265(RASSF2)	--	13.9547959	1656	12.861326	1527	13.07479836	1540	16.87285569	1992	15.86524089	1863	12.351905	1456	0.959353716	0.235483291	normal	0.944939757	0.265262885	normal	0.981469599	-0.089121417	normal	0.525380081	0.147167771	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K09851|0|hsa:9770|RASSF2, CENP-34, RASFADIN; Ras association (RalGDS/AF-6) domain family member 2; K09851 Ras association domain-containing protein 2/4 (A)"	--	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain	Ras association domain-containing protein 2 GN=RASSF2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras association domain-containing protein 2 [Odobenus rosmarus divergens]
ENSG00000101266(CSNK2A1)	--	79.99322045	4499	74.09917701	4132	78.64881882	4245	80.31807215	4858	86.013351	5039	67.27973932	4014	0.992098611	0.079899598	normal	0.970713078	0.264782768	normal	0.990988311	-0.088982774	normal	0.700348431	0.089854121	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K03097|0|ssc:100517435|CSNK2A1; casein kinase 2, alpha 1 polypeptide; K03097 casein kinase II subunit alpha [EC:2.7.11.1] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; NF-kappa B signaling pathway (ko04064);; Wnt signaling pathway (ko04310);; Adherens junction (ko04520);; Tight junction (ko04530);; Measles (ko05162);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[TDK]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Transcription"	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Casein kinase II subunit alpha GN=CSNK2A1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: casein kinase II subunit alpha isoform X1 [Sorex araneus] 
ENSG00000101276(SLC52A3)	--	1.829172855	91	1.567410123	80	1.53457244	76	0.368000217	19	0.53376016	26	0.460620999	23	7.85E-08	-2.201256701	down	0.000559127	-1.587580395	down	0.00038802	-1.66887467	down	9.03E-06	-1.881618549	down	--	--	Cellular Component: integral component of plasma membrane (GO:0005887);; Molecular Function: riboflavin transporter activity (GO:0032217);; Biological Process: riboflavin transport (GO:0032218);; 	"K14620|0|hsa:113278|SLC52A3, BVVLS, BVVLS1, C20orf54, RFT2, RFVT3, bA371L19.1, hRFT2; solute carrier family 52 (riboflavin transporter), member 3; K14620 riboflavin transporter 2 (A)"	Vitamin digestion and absorption (ko04977)	[S]	Function unknown	Protein of unknown function (DUF1011)	"Solute carrier family 52, riboflavin transporter, member 3 GN=SLC52A3 OS=Homo sapiens (Human) PE=1 SV=4"	P	Inorganic ion transport and metabolism	"PREDICTED: solute carrier family 52, riboflavin transporter, member 3 isoform X1 [Tupaia chinensis] "
ENSG00000101280(ANGPT4)	--	0	0	0	0	0	0	0.0110308	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05467|0|hsa:51378|ANGPT4, AGP4, ANG-3, ANG4; angiopoietin 4; K05467 angiopoietin 4 (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; HIF-1 signaling pathway (ko04066);; PI3K-Akt signaling pathway (ko04151)	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-4 (Precursor) GN=ANGPT4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: angiopoietin-4 isoform X1 [Equus caballus] 
ENSG00000101282(RSPO4)	--	0	0	0.063209337	3	0	0	0	0	0	0	0.020715879	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	R-spondin-4 (Precursor) GN=RSPO4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: R-spondin-4 [Camelus bactrianus] 
ENSG00000101290(CDS2)	--	33.65070294	2857	21.67173285	2599	27.8820492	2639	33.04986683	3341	32.51842368	2921	33.81843614	3001	0.979484504	0.194849713	normal	0.983706715	0.146998451	normal	0.980798605	0.177065315	normal	0.363358852	0.172848098	normal	[I]	Lipid transport and metabolism	--	K00981|0|hsa:8760|CDS2; CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 (EC:2.7.7.41); K00981 phosphatidate cytidylyltransferase [EC:2.7.7.41] (A)	Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070)	[I]	Lipid transport and metabolism	Cytidylyltransferase family	Phosphatidate cytidylyltransferase 2 GN=CDS2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: phosphatidate cytidylyltransferase 2 [Trichechus manatus latirostris]
ENSG00000101294(HM13)	--	120.7066709	3139	122.7124563	3261	110.2982501	2966	119.7112626	3207	122.1302611	3316	147.1586441	3965	0.99064278	8.70E-05	normal	0.990610523	0.002701765	normal	0.781448174	0.410329266	normal	0.488156383	0.142531673	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Cellular Component: integral component of membrane (GO:0016021);; 	K09595|0|ptr:469911|HM13; histocompatibility (minor) 13; K09595 minor histocompatibility antigen H13 [EC:3.4.23.-] (A)	--	[S]	Function unknown	Signal peptide peptidase	Minor histocompatibility antigen H13 GN=HM13 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: minor histocompatibility antigen H13 isoform X1 [Pantholops hodgsonii]
ENSG00000101298(SNPH)	--	6.129199676	635	5.546204073	587	6.824520955	721	5.209353372	540	4.0461868	408	4.40434831	459	0.92022484	-0.263935987	normal	0.256945838	-0.54452526	normal	0.029470763	-0.658051621	normal	0.007477772	-0.48715355	normal	--	--	--	--	--	--	--	Golgi-localised syntaxin-1-binding clamp	Syntaphilin GN=SNPH OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: syntaphilin [Galeopterus variegatus]
ENSG00000101306(MYLK2)	--	0.124793231	8	0.061561566	4	0.06019284	3	0.124474226	8	0.106307377	6	0.061798343	4	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K00907|0|hsa:85366|MYLK2, KMLC, MLCK, MLCK2, skMLCK; myosin light chain kinase 2 (EC:2.7.11.18); K00907 myosin-light-chain kinase [EC:2.7.11.18] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	"Myosin light chain kinase 2, skeletal/cardiac muscle GN=MYLK2 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: myosin light chain kinase 2, skeletal/cardiac muscle isoform X3 [Galeopterus variegatus]"
ENSG00000101307(SIRPB1)	--	0.110769054	3	0.036509141	1	0.072856324	2	0.072758894	2	0.177574994	4	0.179713841	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06551|0|ptr:458039|SIRPA; signal-regulatory protein alpha; K06551 signal-regulatory protein alpha/beta1/gamma (A)	Osteoclast differentiation (ko04380)	--	--	Immunoglobulin C1-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	Signal-regulatory protein beta-1 isoform 3 (Precursor) GN=SIRPB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: signal-regulatory protein beta-1 [Galeopterus variegatus]
ENSG00000101310(SEC23B)	--	37.07210258	2156	35.6837048	2063	41.1560364	2355	43.67651938	2537	37.61159069	2163	42.37335664	2450	0.973379107	0.203800085	normal	0.986482452	0.04682976	normal	0.987932038	0.048732565	normal	0.652054186	0.100016068	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: COPII vesicle coat (GO:0030127);; 	"K14006|0|hsa:10483|SEC23B, CDA-II, CDAII, CDAN2, HEMPAS; Sec23 homolog B (S. cerevisiae); K14006 protein transport protein SEC23 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec23/Sec24 trunk domain;; Sec23/Sec24 helical domain;; Sec23/Sec24 beta-sandwich domain;; Gelsolin repeat;; Sec23/Sec24 zinc finger	Protein transport protein Sec23B GN=SEC23B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec23B [Condylura cristata]
ENSG00000101311(FERMT1)	--	6.920125175	607	6.597239374	588	8.740162355	651	12.09403731	1099	11.73487777	1067	8.471234321	752	0.00029684	0.824019493	normal	0.000293831	0.836625794	normal	0.952559743	0.199352455	normal	0.009123184	0.63853683	normal	--	--	--	"K17082|0|hsa:55612|FERMT1, C20orf42, DTGCU2, KIND1, UNC112A, URP1; fermitin family member 1; K17082 kindlin 1 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	FERM central domain;; FERM N-terminal domain;; PH domain	Fermitin family homolog 1 GN=FERMT1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: fermitin family homolog 1 [Odobenus rosmarus divergens]
ENSG00000101323(HAO1)	--	0.0330904	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; 	K11517|0|ptr:747888|HAO1; hydroxyacid oxidase (glycolate oxidase) 1; K11517 (S)-2-hydroxy-acid oxidase [EC:1.1.3.15] (A)	Glyoxylate and dicarboxylate metabolism (ko00630);; Peroxisome (ko04146)	[C]	Energy production and conversion	FMN-dependent dehydrogenase;; Conserved region in glutamate synthase	Hydroxyacid oxidase 1 GN=HAO1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: hydroxyacid oxidase 1 [Equus caballus]
ENSG00000101331(CCM2L)	--	0.031842364	1	0.030854613	1	0	0	0.111866573	5	0.246000471	8	0.093529519	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cerebral cavernous malformations 2 protein-like GN=CCM2L OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: cerebral cavernous malformations 2 protein-like isoform 2 [Orcinus orca]
ENSG00000101333(PLCB4)	--	9.104083875	788	14.99438595	869	14.2200809	989	12.64642869	933	13.92027132	918	10.69638399	708	0.951455495	0.212468136	normal	0.976439412	0.057613864	normal	0.382746511	-0.489623478	normal	0.823635938	-0.069860343	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05858|0|hsa:5332|PLCB4, ARCND2, PI-PLC; phospholipase C, beta 4 (EC:3.1.4.11); K05858 phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Chemokine signaling pathway (ko04062);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Huntington's disease (ko05016);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Pathways in cancer (ko05200)	[I]	Lipid transport and metabolism	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; Protein of unknown function (DUF1154);; C2 domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 GN=PLCB4 OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 isoform X1 [Sorex araneus]"
ENSG00000101335(MYL9)	--	0.016192903	1	0.044862	3	0	0	3.482710258	135	6.872330246	264	1.856151098	68	0	5.729024502	up	0	5.861004407	up	2.66E-15	5.518413082	up	6.65E-05	6.842302246	up	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K12755|8.96971e-110|tup:102483320|MYL9; myosin, light chain 9, regulatory; K12755 myosin regulatory light chain 9 (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921)	[Z]	Cytoskeleton	EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand	Myosin regulatory light polypeptide 9 GN=MYL9 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	Myosin regulatory light polypeptide 9 [Pteropus alecto]
ENSG00000101336(HCK)	--	0.031063023	1	0.023432602	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08893|0|hsa:3055|HCK, JTK9, p59Hck, p61Hck; HCK proto-oncogene, Src family tyrosine kinase (EC:2.7.10.2); K08893 hemopoietic cell kinase [EC:2.7.10.2] (A)"	Chemokine signaling pathway (ko04062);; Fc gamma R-mediated phagocytosis (ko04666)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Tyrosine-protein kinase HCK GN=HCK OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase HCK [Canis lupus familiaris]
ENSG00000101337(TM9SF4)	--	27.230784	2079	26.52263865	2013	24.66384	1871	19.98782602	1515	24.2658	1839	25.254867	1928	0.399647554	-0.486980644	normal	0.978650991	-0.151732937	normal	0.986082011	0.034976201	normal	0.284320604	-0.195539434	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17086|0|pps:100974978|TM9SF4; transmembrane 9 superfamily protein member 4; K17086 transmembrane 9 superfamily member 2/4 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endomembrane protein 70	Transmembrane 9 superfamily member 4 (Precursor) GN=TM9SF4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane 9 superfamily member 4 isoform X1 [Vicugna pacos]
ENSG00000101342(TLDC2)	--	0.0845627	2	0.336312	8	0.0831055	1	0.0832595	2	0.329025	7	0.416063	10	--	--	--	--	--	--	--	--	--	--	--	--	[L]	"Replication, recombination and repair"	--	--	--	[L]	"Replication, recombination and repair"	TLD	TLD domain-containing protein 2 GN=TLDC2 OS=Homo sapiens (Human) PE=2 SV=1	L	"Replication, recombination and repair"	PREDICTED: TLD domain-containing protein 2 [Ursus maritimus]
ENSG00000101343(CRNKL1)	--	13.48840812	982	14.39232304	1051	14.32012483	1029	13.34050805	982	12.92879788	940	12.9912128	946	0.978985741	-0.030784099	normal	0.962729332	-0.182179204	normal	0.972303493	-0.129423891	normal	0.614411852	-0.115733661	normal	[R]	General function prediction only	Cellular Component: nucleus (GO:0005634);; Biological Process: RNA processing (GO:0006396);; Biological Process: mRNA processing (GO:0006397);; 	"K12869|0|hsa:51340|CRNKL1, CLF, CRN, Clf1, HCRN, MSTP021, SYF3; crooked neck pre-mRNA splicing factor 1; K12869 crooked neck (A)"	Spliceosome (ko03040)	[D]	"Cell cycle control, cell division, chromosome partitioning"	HAT (Half-A-TPR) repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Suppressor of forked protein (Suf);; Tetratricopeptide repeat	Crooked neck-like protein 1 GN=CRNKL1 OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: crooked neck-like protein 1 [Odobenus rosmarus divergens]
ENSG00000101346(POFUT1)	--	31.44371	2917	30.32935	2867	31.756419	2955	34.926801	3237	31.424558	2886	29.189887	2686	0.987215632	0.11928006	normal	0.989597677	-0.011890911	normal	0.984304295	-0.145911911	normal	0.978281315	-0.010218493	normal	--	--	--	"K03691|0|ptr:449504|POFUT1, fut12; protein O-fucosyltransferase 1 (EC:2.4.1.221); K03691 peptide-O-fucosyltransferase [EC:2.4.1.221] (A)"	Other types of O-glycan biosynthesis (ko00514)	[O]	"Posttranslational modification, protein turnover, chaperones"	GDP-fucose protein O-fucosyltransferase	GDP-fucose protein O-fucosyltransferase 1 (Precursor) GN=POFUT1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: GDP-fucose protein O-fucosyltransferase 1 isoform X1 [Condylura cristata]
ENSG00000101347(SAMHD1)	--	5.736999793	497	4.849115619	421	5.391646634	464	9.04472	790	8.874228013	767	6.541439	568	0.041986605	0.636201937	normal	0.00047699	0.841707893	normal	0.906465024	0.282640754	normal	0.005683263	0.598678624	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	HD domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 GN=SAMHD1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: deoxynucleoside triphosphate triphosphohydrolase SAMHD1 [Equus caballus]
ENSG00000101349(PAK5)	--	0	0	0.035028749	3	0.04622942	3	0	0	0	0	0.011502926	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05736|0|hsa:57144|PAK7, PAK5; p21 protein (Cdc42/Rac)-activated kinase 7 (EC:2.7.11.1); K05736 p21-activated kinase 7 [EC:2.7.11.1] (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Axon guidance (ko04360);; Focal adhesion (ko04510);; T cell receptor signaling pathway (ko04660);; Regulation of actin cytoskeleton (ko04810);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; P21-Rho-binding domain;; Kinase-like	Serine/threonine-protein kinase PAK 7 GN=PAK7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase PAK 7 isoformX1 [Canis lupus familiaris]
ENSG00000101350(KIF3B)	--	17.475	2354	17.8647	2419	18.2768	2450	17.0938	2304	17.3825	2322	16.8681	2264	0.987303597	-0.061765117	normal	0.986472222	-0.080418035	normal	0.984312445	-0.122120794	normal	0.695199456	-0.089282205	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10394|0|ptr:458166|KIF3B; kinesin family member 3B; K10394 kinesin family member 3/17 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	"Kinesin-like protein KIF3B, N-terminally processed GN=KIF3B OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF3B [Loxodonta africana] 
ENSG00000101353(MROH8)	--	1.267598322	26	1.286000062	23	0.986074953	24	0.51140015	20	1.093094758	23	0.578585002	26	0.982198762	-0.383434159	normal	0.986760141	-0.020104667	normal	0.986309422	0.101066018	normal	0.940575645	-0.101698694	normal	--	--	--	--	--	[S]	Function unknown	--	Protein MROH8 GN=MROH8 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: HEAT repeat-containing protein 8 [Odobenus rosmarus divergens]
ENSG00000101361(NOP56)	--	87.811751	4024	81.9274796	3842	85.27991769	4016	99.72632498	4587	98.95830717	4573	70.08650956	3234	0.987630578	0.158031797	normal	0.97781551	0.229773857	normal	0.933790087	-0.320596224	normal	0.909622586	0.0388056	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K14564|0|hsa:10528|NOP56, NOL5A, SCA36; NOP56 ribonucleoprotein; K14564 nucleolar protein 56 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	Putative snoRNA binding domain;; NOSIC (NUC001) domain;; NOP5NT (NUC127) domain	Nucleolar protein 56 GN=NOP56 OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	hypothetical protein PANDA_007374 [Ailuropoda melanoleuca]
ENSG00000101363(MANBAL)	--	46.460903	1012	51.7897672	1148	49.48551	1144	53.157138	1171	56.1607	1216	53.915193	1164	0.965135774	0.179446099	normal	0.97969479	0.061515288	normal	0.981148167	0.01669069	normal	0.73222535	0.082907509	normal	--	--	--	--	--	--	--	Uncharacterised protein family (UPF0239)	Protein MANBAL GN=MANBAL OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein MANBAL isoform 1 [Dasypus novemcinctus] 
ENSG00000101365(IDH3B)	--	57.912058	1602	57.65559467	1627	56.69842	1593	58.069607	1643	57.644389	1592	60.434493	1682	0.984842369	0.005620746	normal	0.983567892	-0.052750904	normal	0.983483448	0.07007525	normal	0.985612711	0.00698623	normal	[CE]	Energy production and conversion;; Amino acid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00030|0|ptr:458048|IDH3B; isocitrate dehydrogenase 3 (NAD+) beta; K00030 isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] (A)	Citrate cycle (TCA cycle) (ko00020);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Isocitrate/isopropylmalate dehydrogenase	"Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial (Precursor) GN=IDH3B OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isoform 1 [Trichechus manatus latirostris]"
ENSG00000101367(MAPRE1)	--	113.0800105	4879	111.2630076	4852	111.2930086	4784	129.7860127	5654	116.434193	5002	113.7370163	4904	0.987484188	0.18180092	normal	0.993051165	0.022492045	normal	0.993136177	0.027441579	normal	0.745578626	0.078615456	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: microtubule binding (GO:0008017);; 	"K10436|0|pps:100970540|MAPRE1; microtubule-associated protein, RP/EB family, member 1; K10436 microtubule-associated protein, RP/EB family (A)"	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	EB1-like C-terminal motif;; Calponin homology (CH) domain	Microtubule-associated protein RP/EB family member 1 GN=MAPRE1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: microtubule-associated protein RP/EB family member 1 [Tupaia chinensis]
ENSG00000101384(JAG1)	--	14.00832033	1517	12.7958036	1343	15.04031993	1674	22.33215073	2464	24.98255197	2765	16.32678053	1816	0.011413172	0.668412973	normal	2.36E-07	1.019576738	up	0.981875914	0.1090786	normal	0.027069521	0.614233014	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: cell communication (GO:0007154);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06052|0|hsa:182|JAG1, AGS, AHD, AWS, CD339, HJ1, JAGL1; jagged 1; K06052 jagged (A)"	Notch signaling pathway (ko04330);; TNF signaling pathway (ko04668)	[T]	Signal transduction mechanisms	EGF-like domain;; N terminus of Notch ligand;; Delta serrate ligand;; EGF-like domain;; Human growth factor-like EGF;; Calcium-binding EGF domain	Protein jagged-1 (Precursor) GN=JAG1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein jagged-1 [Equus przewalskii]
ENSG00000101391(CDK5RAP1)	--	11.68159392	467	11.87283433	488	12.19146316	495	13.93270398	566	14.21661499	567	13.11521543	527	0.929443548	0.245811772	normal	0.949616848	0.194481493	normal	0.968987431	0.081840639	normal	0.488005002	0.173804517	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; Molecular Function: 4 iron, 4 sulfur cluster binding (GO:0051539);; "	--	--	[T]	Signal transduction mechanisms	Radical SAM superfamily;; Uncharacterized protein family UPF0004;; TRAM domain	CDK5 regulatory subunit-associated protein 1 GN=CDK5RAP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: CDK5 regulatory subunit-associated protein 1 [Myotis davidii]
ENSG00000101400(SNTA1)	--	14.97681	598	13.476643	573	14.0298	540	8.00076	325	8.097669881	341	8.253701498	350	0.000120044	-0.907323587	normal	0.004889543	-0.767533056	normal	0.070198347	-0.63168098	normal	1.89E-05	-0.773026811	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	PDZ domain (Also known as DHR or GLGF);; PH domain	Alpha-1-syntrophin GN=SNTA1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: alpha-1-syntrophin [Ceratotherium simum simum]
ENSG00000101407(TTI1)	--	13.06084786	990	14.81236742	1111	14.331739	1083	15.19321726	1095	11.98900022	888	13.78725483	1040	0.974683796	0.114429276	normal	0.850145524	-0.344128611	normal	0.978648052	-0.06664618	normal	0.688053297	-0.096268508	normal	--	--	--	--	--	[S]	Function unknown	HEAT repeats	TELO2-interacting protein 1 homolog GN=TTI1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: TELO2-interacting protein 1 homolog [Galeopterus variegatus]
ENSG00000101412(E2F1)	--	26.3927	1235	25.17	1201	28.3982	1361	18.4863	867	20.5335	955	19.0116	892	0.186287721	-0.54043229	normal	0.840736143	-0.351592375	normal	0.0430949	-0.61698959	normal	0.000886717	-0.505290028	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K17454|0|hsa:1869|E2F1, E2F-1, RBAP1, RBBP3, RBP3; E2F transcription factor 1; K17454 transcription factor E2F1 (A)"	Cell cycle (ko04110);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[K]	Transcription	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F1 GN=E2F1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor E2F1 [Lipotes vexillifer]
ENSG00000101413(RPRD1B)	--	13.26368	789	11.77987473	740	13.316463	825	13.000733	827	13.42254	862	13.02566503	830	0.976506778	0.036959467	normal	0.954625525	0.19836016	normal	0.977423552	0.000424998	normal	0.775160352	0.076734105	normal	--	--	--	K15559|0|umr:103669770|RPRD1B; regulation of nuclear pre-mRNA domain containing 1B; K15559 regulator of Ty1 transposition protein 103 (A)	--	[A]	RNA processing and modification	RNA polymerase II-binding domain.	Regulation of nuclear pre-mRNA domain-containing protein 1B GN=RPRD1B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: regulation of nuclear pre-mRNA domain-containing protein 1B [Eptesicus fuscus]
ENSG00000101417(PXMP4)	--	6.006593005	274	4.177116617	247	6.479671436	299	5.284935298	258	3.830857672	212	4.764937809	279	0.961218615	-0.116961044	normal	0.934214975	-0.240283571	normal	0.962490618	-0.107608243	normal	0.659599028	-0.151425559	normal	--	--	--	"K13350|1.53996e-139|pps:100971111|PXMP4; peroxisomal membrane protein 4, 24kDa; K13350 peroxisomal membrane protein 4 (A)"	Peroxisome (ko04146)	--	--	Tim17/Tim22/Tim23/Pmp24 family	Peroxisomal membrane protein 4 GN=PXMP4 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein 4 [Myotis davidii] 
ENSG00000101421(CHMP4B)	--	73.4107	2311	77.3502	2538	75.7467	2474	99.2137	3178	105.738	3323	95.8462	3032	0.696785713	0.428525766	normal	0.871132574	0.36717595	normal	0.948097758	0.284975202	normal	0.021279176	0.359221456	normal	--	--	Biological Process: vacuolar transport (GO:0007034);; 	K12194|1.06967e-97|nle:100599282|CHMP4B; charged multivesicular body protein 4B; K12194 charged multivesicular body protein 4 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snf7	Charged multivesicular body protein 4b GN=CHMP4B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 4b [Oryctolagus cuniculus] 
ENSG00000101439(CST3)	--	318.71766	3865	320.97575	3984	306.48989	3828	298.47994	3688	307.29778	3814	316.37243	3893	0.990020238	-0.098421962	normal	0.99050184	-0.08430665	normal	0.991889621	0.015993807	normal	0.826877892	-0.056336121	normal	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	K13899|6.05127e-81|ptr:743081|CST3; cystatin C; K13899 cystatin-C (A)	Salivary secretion (ko04970)	--	--	Cystatin domain	Cystatin-C (Precursor) GN=CST3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cystatin-C-like [Loxodonta africana]
ENSG00000101440(ASIP)	--	0.335883	2	0.16546	1	0.153828	0	0.471708	3	0.32674	1	0.163251	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: hormone-mediated signaling pathway (GO:0009755);; 	"K08725|7.05465e-25|hsa:434|ASIP, AGSW, AGTI, AGTIL, ASP, SHEP9; agouti signaling protein; K08725 agouti signaling protein (A)"	Melanogenesis (ko04916)	--	--	Agouti protein	Agouti-signaling protein (Precursor) GN=ASIP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: agouti-signaling protein [Camelus dromedarius] 
ENSG00000101441(CST4)	--	0	0	0	0	0	0	0	0	0	0	0.103015	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	K13900|8.51542e-87|hsa:1472|CST4; cystatin S; K13900 cystatin-S (A)	Salivary secretion (ko04970)	--	--	Cystatin domain	Cystatin-S (Precursor) GN=CST4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: cystatin-C-like [Loxodonta africana]
ENSG00000101442(ACTR5)	--	5.974205	305	5.13065	270	5.7757	297	4.820477	246	6.458317	327	5.737566	293	0.867990938	-0.339076931	normal	0.925523845	0.253612271	normal	0.967475694	-0.027711643	normal	0.949356766	-0.030465405	normal	[Z]	Cytoskeleton	--	"K11672|0|hsa:79913|ACTR5, Arp5, INO80M; ARP5 actin-related protein 5 homolog (yeast); K11672 actin-related protein 5 (A)"	--	[Z]	Cytoskeleton	Actin	Actin-related protein 5 GN=ACTR5 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: actin-related protein 5 [Galeopterus variegatus]
ENSG00000101443(WFDC2)	--	0.894947523	1	0	0	0	0	0	0	0.329653	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Molecular Function: peptidase inhibitor activity (GO:0030414);; 	--	--	--	--	WAP-type (Whey Acidic Protein) 'four-disulfide core'	WAP four-disulfide core domain protein 2 (Precursor) GN=WFDC2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	WAP four-disulfide core domain protein 2 precursor [Canis lupus familiaris] 
ENSG00000101444(AHCY)	--	158.0740035	6321	154.2490025	6266	160.3640028	6510	148.1990025	5935	138.710114	5497	145.6010031	5828	0.99240809	-0.12170651	normal	0.985428025	-0.210272619	normal	0.989963526	-0.167906861	normal	0.412560879	-0.167125534	normal	[H]	Coenzyme transport and metabolism	Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	K01251|0|pps:100974216|AHCY; adenosylhomocysteinase; K01251 adenosylhomocysteinase [EC:3.3.1.1] (A)	Cysteine and methionine metabolism (ko00270)	[H]	Coenzyme transport and metabolism	"S-adenosyl-L-homocysteine hydrolase;; S-adenosyl-L-homocysteine hydrolase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; Acetohydroxy acid isomeroreductase, catalytic domain"	Adenosylhomocysteinase GN=AHCY OS=Homo sapiens (Human) PE=1 SV=4	H	Coenzyme transport and metabolism	PREDICTED: adenosylhomocysteinase isoform 1 [Orcinus orca]
ENSG00000101445(PPP1R16B)	--	1.0941173	142	0.302400329	38	0.745794858	97	0.422308678	54	0.8731017	111	0.45568069	59	3.07E-05	-1.400150617	down	0.000110912	1.488836749	up	0.575721185	-0.711199746	normal	0.794088581	-0.326631909	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17459|0|pps:100991428|PPP1R16B; protein phosphatase 1, regulatory subunit 16B; K17459 protein phosphatase 1 regulatory inhibitor subunit 16B (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Protein phosphatase 1 regulatory inhibitor subunit 16B (Precursor) GN=PPP1R16B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory inhibitor subunit 16B isoform X1 [Tupaia chinensis] 
ENSG00000101447(FAM83D)	--	30.79147	1279	24.31371	1013	30.2968	1256	34.052	1413	31.3802	1295	25.86967	1076	0.978271619	0.112784008	normal	0.872365531	0.332451447	normal	0.950824792	-0.231148814	normal	0.815138112	0.071138523	normal	--	--	--	"K16805|0|hsa:81610|FAM83D, C20orf129, CHICA, dJ616B8.3; family with sequence similarity 83, member D; K16805 protein FAM83D (A)"	--	--	--	Protein of unknown function (DUF1669);; PLD-like domain	Protein FAM83D GN=FAM83D OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM83D [Trichechus manatus latirostris]
ENSG00000101452(DHX35)	--	4.9951211	308	4.632039745	247	4.617956895	277	5.122569226	312	5.329567342	325	5.134580109	291	0.967905621	-0.012156336	normal	0.82653017	0.37250835	normal	0.965959913	0.062508752	normal	0.68604178	0.136230014	normal	[L]	"Replication, recombination and repair"	Molecular Function: helicase activity (GO:0004386);; 	K13117|0|ggo:101130028|DHX35; probable ATP-dependent RNA helicase DHX35; K13117 ATP-dependent RNA helicase DDX35 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase	Probable ATP-dependent RNA helicase DHX35 GN=DHX35 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DHX35 isoform 1 [Ceratotherium simum simum]
ENSG00000101457(DNTTIP1)	--	12.03291006	327	10.6543099	294	11.75080836	328	13.87823208	377	14.1279689	372	12.50944027	341	0.952571073	0.173681171	normal	0.882297858	0.316609225	normal	0.967504084	0.04756937	normal	0.545592236	0.178499508	normal	--	--	--	"K08707|0|ptr:469955|DNTTIP1; deoxynucleotidyltransferase, terminal, interacting protein 1; K08707 deoxynucleotidyltransferase terminal-interacting protein 1 (A)"	--	[T]	Signal transduction mechanisms	--	Deoxynucleotidyltransferase terminal-interacting protein 1 GN=DNTTIP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: deoxynucleotidyltransferase terminal-interacting protein 1 isoform X1 [Felis catus]
ENSG00000101460(MAP1LC3A)	--	16.0953	243	10.92876	191	12.9892	205	11.34152	150	12.71387	181	11.14572388	199	0.081445072	-0.720963668	normal	0.96225899	-0.098210568	normal	0.966041834	-0.050766792	normal	0.386034987	-0.290192195	normal	--	--	Biological Process: autophagic vacuole assembly (GO:0000045);; Cellular Component: cytoplasm (GO:0005737);; 	K10435|9.47114e-76|cmy:102942591|uncharacterized LOC102942591; K10435 microtubule-associated protein 1 light chain (A)	--	[Z]	Cytoskeleton	Autophagy protein Atg8 ubiquitin like;; Ubiquitin-like autophagy protein Apg12	Microtubule-associated proteins 1A/1B light chain 3A (Precursor) GN=MAP1LC3A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: microtubule-associated proteins 1A/1B light chain 3A [Vicugna pacos]
ENSG00000101463(SYNDIG1)	--	0.0417278	2	0	0	0.0594714	2	0.0415658	2	0.202389	9	0.0823657	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced transmembrane protein	Synapse differentiation-inducing gene protein 1 GN=SYNDIG1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: synapse differentiation-inducing gene protein 1-like isoform X1 [Mustela putorius furo] 
ENSG00000101464(PIGU)	--	27.71765737	552	30.25230068	601	27.13385459	539	23.28921103	470	22.31376416	447	27.89575051	556	0.920175734	-0.262048254	normal	0.597705096	-0.447206698	normal	0.97219473	0.03640759	normal	0.337790512	-0.220825718	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: attachment of GPI anchor to protein (GO:0016255);; Cellular Component: GPI-anchor transamidase complex (GO:0042765);; 	"K05293|0|pps:100976896|PIGU; phosphatidylinositol glycan anchor biosynthesis, class U; K05293 phosphatidylinositol glycan, class U (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[R]	General function prediction only	GPI transamidase subunit PIG-U	Phosphatidylinositol glycan anchor biosynthesis class U protein GN=PIGU OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: phosphatidylinositol glycan anchor biosynthesis class U protein isoform X1 [Erinaceus europaeus]
ENSG00000101470(TNNC2)	--	0.229413	3	0	0	0	0	0	0	0.0853127	0	0.225482	3	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	"K12042|6.60453e-95|ptr:741787|TNNC2; troponin C type 2 (fast); K12042 troponin C, skeletal muscle (A)"	Calcium signaling pathway (ko04020)	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain;; Cytoskeletal-regulatory complex EF hand;; Secreted protein acidic and rich in cysteine Ca binding region	"Troponin C, skeletal muscle GN=TNNC2 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: troponin C, skeletal muscle [Trichechus manatus latirostris] "
ENSG00000101473(ACOT8)	--	10.94423405	196	6.578405	121	9.804266	172	8.737274	163	9.18885137	170	9.977534022	192	0.920012845	-0.294280029	normal	0.788662654	0.464185624	normal	0.958457915	0.149164432	normal	0.874432846	0.082028135	normal	[I]	Lipid transport and metabolism	--	"K11992|0|hsa:10005|ACOT8, HNAACTE, PTE-1, PTE-2, PTE1, PTE2, hACTE-III, hTE; acyl-CoA thioesterase 8 (EC:3.1.2.27); K11992 acyl-CoA thioesterase 8 [EC:3.1.2.27] (A)"	Primary bile acid biosynthesis (ko00120);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Thioesterase-like superfamily;; Acyl-CoA thioesterase	Acyl-coenzyme A thioesterase 8 GN=ACOT8 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-coenzyme A thioesterase 8 isoformX1 [Equus caballus] 
ENSG00000101474(APMAP)	--	79.64762015	3537	77.311073	3523	80.62009	3638	102.11945	4551	95.76249	4204	85.661926	3788	0.928127101	0.332697418	normal	0.975623549	0.233439807	normal	0.991249313	0.049978984	normal	0.254720178	0.207858188	normal	[G]	Carbohydrate transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: strictosidine synthase activity (GO:0016844);; 	--	--	[R]	General function prediction only	Strictosidine synthase;; SMP-30/Gluconolaconase/LRE-like region	Adipocyte plasma membrane-associated protein GN=APMAP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: adipocyte plasma membrane-associated protein [Oryctolagus cuniculus]
ENSG00000101489(CELF4)	--	0.163335127	7	0.092890434	4	0.25256748	10	0.022992948	1	0	0	0.022860841	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13207|0|pale:102878430|CELF4; CUGBP, Elav-like family member 4; K13207 CUG-BP- and ETR3-like factor (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	CUGBP Elav-like family member 4 GN=CELF4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: CUGBP Elav-like family member 4 isoform X16 [Mustela putorius furo] 
ENSG00000101493(ZNF516)	--	2.905990677	417	3.349888404	403	2.605421	388	2.579960736	375	3.065308018	351	2.526323952	369	0.950806542	-0.183276499	normal	0.938702268	-0.219850526	normal	0.966403867	-0.080405877	normal	0.571351078	-0.163043495	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain"	Zinc finger protein 516 GN=ZNF516 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 516 [Tupaia chinensis]
ENSG00000101544(ADNP2)	--	12.25948277	1127	12.68565297	1163	11.7261233	1017	12.32599136	1141	13.89408204	1278	12.81999616	1159	0.980932399	-0.013003369	normal	0.976446985	0.114468156	normal	0.965092139	0.180018528	normal	0.696304458	0.092330655	normal	--	--	--	--	--	--	--	--	ADNP homeobox protein 2 GN=ADNP2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ADNP homeobox protein 2 isoform X1 [Sus scrofa] 
ENSG00000101546(RBFA)	--	18.48867	487	16.56915	442	19.06632	518	16.014338	434	15.602575	412	14.72391	397	0.948192197	-0.196402131	normal	0.962143033	-0.122394723	normal	0.758243492	-0.390797305	normal	0.315540296	-0.240482184	normal	--	--	Biological Process: rRNA processing (GO:0006364);; 	--	--	[R]	General function prediction only	Ribosome-binding factor A	"Putative ribosome-binding factor A, mitochondrial (Precursor) GN=RBFA OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: putative ribosome-binding factor A, mitochondrial [Myotis lucifugus]"
ENSG00000101557(USP14)	--	41.069549	2026	41.70936072	2034	42.54079031	2036	42.21104506	2114	41.14172202	2113	37.25349	1863	0.986952238	0.030486306	normal	0.98658079	0.033522077	normal	0.980826092	-0.136295457	normal	0.940882927	-0.022948105	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11843|0|fca:101091976|USP14; ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase); K11843 ubiquitin carboxyl-terminal hydrolase 14 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 14 GN=USP14 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 14 [Felis catus]
ENSG00000101558(VAPA)	--	37.79819953	2063	34.71877217	2044	34.23264075	1870	40.5860929	2181	41.41105445	2248	43.80168727	2163	0.986790599	0.049377919	normal	0.983433054	0.115738608	normal	0.971234252	0.201552274	normal	0.5711589	0.119939497	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K06096|0|hsa:9218|VAPA, VAP-33, VAP-A, VAP33, hVAP-33; VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; K06096 vesicle-associated membrane protein-associated protein A (A)"	Tight junction (ko04530)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	MSP (Major sperm protein) domain	Vesicle-associated membrane protein-associated protein A GN=VAPA OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein-associated protein A isoform X1 [Tupaia chinensis]
ENSG00000101574(METTL4)	--	3.6645316	163	4.311386807	186	3.69314604	173	3.439450267	134	3.447655701	148	4.580819983	190	0.921243248	-0.310239834	normal	0.891333	-0.347952874	normal	0.961176935	0.125885558	normal	0.699047465	-0.16544779	normal	--	--	Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[KT]	Transcription;; Signal transduction mechanisms	MT-A70	Methyltransferase-like protein 4 GN=METTL4 OS=Homo sapiens (Human) PE=2 SV=3	KT	Transcription;; Signal transduction mechanisms	PREDICTED: methyltransferase like 4 isoform X1 [Equus caballus] 
ENSG00000101577(LPIN2)	--	8.733866	986	8.921731	908	7.37703506	867	8.81769276	1082	9.4371032	1063	12.43627622	1531	0.975680818	0.103055359	normal	0.956233085	0.205634043	normal	0.000277653	0.811000343	normal	0.205321542	0.392643918	normal	[R]	General function prediction only	--	K15728|0|hsa:9663|LPIN2; lipin 2 (EC:3.1.3.4); K15728 phosphatidate phosphatase LPIN [EC:3.1.3.4] (A)	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[NI]	Cell motility;; Lipid transport and metabolism	"LNS2 (Lipin/Ned1/Smp2);; lipin, N-terminal conserved region"	Phosphatidate phosphatase LPIN2 GN=LPIN2 OS=Homo sapiens (Human) PE=1 SV=1	IN	Lipid transport and metabolism;; Cell motility	PREDICTED: phosphatidate phosphatase LPIN2 [Oryctolagus cuniculus]
ENSG00000101596(SMCHD1)	--	9.09236236	1385	9.529002701	1436	11.1184746	1572	8.91071838	1375	8.291082627	1250	7.920808277	1191	0.982615784	-0.041240705	normal	0.957610299	-0.221304174	normal	0.708423461	-0.408266513	normal	0.212544083	-0.224594798	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: chromosome (GO:0005694);; Biological Process: chromosome organization (GO:0051276);; 	--	--	--	--	"SMC proteins Flexible Hinge Domain;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	Structural maintenance of chromosomes flexible hinge domain-containing protein 1 GN=SMCHD1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: structural maintenance of chromosomes flexible hinge domain-containing protein 1 [Galeopterus variegatus]
ENSG00000101605(MYOM1)	--	0.365407031	50	0.273610893	38	0.336361	46	0.115782757	16	0.169435975	23	0.223965822	31	0.023737927	-1.584257397	normal	0.922646095	-0.709151862	normal	0.941903983	-0.555282246	normal	0.086047881	-0.955901936	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Tissue factor;; Alphaherpesvirus glycoprotein I	Myomesin-1 GN=MYOM1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: myomesin-1 isoform X1 [Equus caballus]
ENSG00000101608(MYL12A)	--	146.9895204	3031	149.852425	3075	144.8906634	2958	169.740831	3464	148.8151409	2863	138.076086	2835	0.984359006	0.161736086	normal	0.986285189	-0.124421864	normal	0.988939408	-0.069528446	normal	0.986743899	-0.006405356	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K12757|2.0813e-113|ptr:455314|MYL12A; myosin, light chain 12A, regulatory, non-sarcomeric; K12757 myosin regulatory light chain 12 (A)"	Focal adhesion (ko04510);; Tight junction (ko04530);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810)	[Z]	Cytoskeleton	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand	Myosin regulatory light chain 12A GN=MYL12A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	Myosin regulatory light polypeptide 9 [Myotis brandtii]
ENSG00000101624(CEP76)	--	3.381172	173	5.950528767	203	4.120295023	230	3.6652406	193	3.245811087	181	3.102783211	174	0.961149597	0.12593731	normal	0.950834063	-0.185452499	normal	0.813709066	-0.407745368	normal	0.676191309	-0.16631017	normal	--	--	--	K16457|0|mcf:102120693|CEP76; centrosomal protein 76kDa; K16457 centrosomal protein CEP76 (A)	--	--	--	CEP76 C2 domain	Centrosomal protein of 76 kDa GN=CEP76 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centrosomal protein of 76 kDa isoform X1 [Tupaia chinensis]
ENSG00000101638(ST8SIA5)	--	0	0	0	0	0	0	0.020710207	1	0.00772825	1	0.041115708	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03369|0|mcf:102116589|ST8SIA5; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5; K03369 alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8E) [EC:2.4.99.-] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-2,8-sialyltransferase 8E GN=ST8SIA5 OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-2,8-sialyltransferase 8E isoform X1 [Tupaia chinensis] "
ENSG00000101639(CEP192)	--	4.855941548	747	4.496736201	652	5.399726092	772	4.247039192	618	4.163324302	614	4.63714871	670	0.889739878	-0.303645783	normal	0.968287119	-0.107802149	normal	0.948687818	-0.212284411	normal	0.32106434	-0.211593147	normal	--	--	--	"K16725|0|hsa:55125|CEP192, PPP1R62; centrosomal protein 192kDa; K16725 centrosomal protein CEP192 (A)"	--	--	--	--	Centrosomal protein of 192 kDa GN=CEP192 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 192 kDa [Ceratotherium simum simum]
ENSG00000101654(RNMT)	--	9.418847863	968	10.993558	1153	10.46935658	1007	8.82654205	943	8.874186949	860	10.3549051	1099	0.977193397	-0.068471422	normal	0.585298313	-0.443733967	normal	0.974572957	0.117667063	normal	0.570902998	-0.129096757	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K00565|0|hsa:8731|RNMT, MET, RG7MT1, hCMT1c; RNA (guanine-7-) methyltransferase (EC:2.1.1.56); K00565 mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56] (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	mRNA capping enzyme;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain	mRNA cap guanine-N7 methyltransferase GN=RNMT OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: mRNA cap guanine-N7 methyltransferase isoform X1 [Mustela putorius furo] 
ENSG00000101665(SMAD7)	--	7.781632	433	9.53517	474	9.010368	473	18.89020287	1013	16.662962	894	13.12193	643	2.30E-09	1.19251713	up	8.95E-05	0.891856208	normal	0.627251046	0.433493914	normal	0.00239652	0.863409583	normal	--	--	"Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04677|0|ptr:455411|SMAD7; SMAD family member 7; K04677 mothers against decapentaplegic homolog 6/7 (A)	Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain	Mothers against decapentaplegic homolog 7 GN=SMAD7 OS=Homo sapiens (Human) PE=1 SV=1	KT	Transcription;; Signal transduction mechanisms	PREDICTED: mothers against decapentaplegic homolog 7 [Trichechus manatus latirostris]
ENSG00000101670(LIPG)	--	0.990856747	58	0.954508846	68	1.061301775	48	0.722701129	43	1.097969476	49	2.247312603	107	0.945951257	-0.448689036	normal	0.920478216	-0.481506388	normal	0.013803067	1.123892855	normal	0.880880834	0.174747969	normal	--	--	--	--	--	--	--	Putative binding domain	Protein PPP5D1 GN=PPP5D1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	--
ENSG00000101680(LAMA1)	--	0.019098556	4	0.010909749	2	0	0	0	0	0.005366808	0	0.027449114	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Biological Process: cell adhesion (GO:0007155);; Biological Process: regulation of cell adhesion (GO:0030155);; Biological Process: regulation of cell migration (GO:0030334);; Biological Process: regulation of embryonic development (GO:0045995);; 	"K05637|0|hsa:284217|LAMA1, LAMA, PTBHS, S-LAM-alpha; laminin, alpha 1; K05637 laminin, alpha 1/2 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin G domain;; Laminin EGF-like (Domains III and V);; Laminin G domain;; Laminin B (Domain IV);; Laminin N-terminal (Domain VI);; Laminin Domain I;; Laminin Domain II;; Concanavalin A-like lectin/glucanases superfamily	Laminin subunit alpha-1 (Precursor) GN=LAMA1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: laminin subunit alpha-1 [Ceratotherium simum simum]
ENSG00000101695(RNF125)	--	0.29497401	27	0.353344	30	0.284385	23	0.2414123	21	0.272631142	25	0.2405825	20	0.981873535	-0.369496594	normal	0.981229586	-0.269554693	normal	0.986945332	-0.196088414	normal	0.742874168	-0.299148296	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metal ion binding (GO:0046872);; 	"K12170|8.44192e-171|hsa:54941|RNF125, TRAC-1, TRAC1; ring finger protein 125, E3 ubiquitin protein ligase; K12170 E3 ubiquitin-protein ligase RNF125 [EC:6.3.2.19] (A)"	RIG-I-like receptor signaling pathway (ko04622)	--	--	"Drought induced 19 protein (Di19), zinc-binding;; Ring finger domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	E3 ubiquitin-protein ligase RNF125 GN=RNF125 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF125 [Equus caballus] 
ENSG00000101745(ANKRD12)	--	5.406164374	930	14.7287658	1246	6.2424509	901	3.75014548	749	4.055623258	813	6.918848311	1088	0.843211361	-0.342465351	normal	0.034445198	-0.636439336	normal	0.93075212	0.263385247	normal	0.553574179	-0.235994788	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 12 GN=ANKRD12 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 12 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000101751(POLI)	--	6.849850127	412	8.367997222	409	8.950912713	401	7.759577518	374	7.77072312	441	7.915482377	452	0.95398173	-0.169773459	normal	0.965924464	0.08694163	normal	0.955991037	0.163846772	normal	0.940283296	0.031544672	normal	[L]	"Replication, recombination and repair"	Molecular Function: damaged DNA binding (GO:0003684);; Biological Process: DNA repair (GO:0006281);; 	"K03510|0|hsa:11201|POLI, RAD30B, RAD3OB; polymerase (DNA directed) iota (EC:2.7.7.7); K03510 DNA polymerase iota [EC:2.7.7.7] (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	impB/mucB/samB family;; impB/mucB/samB family C-terminal domain	DNA polymerase iota GN=POLI OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase iota [Galeopterus variegatus]
ENSG00000101752(MIB1)	--	14.30197	2033	15.72585	2165	12.58512045	1880	13.62793	1949	13.82125	1910	12.57651	1826	0.9844857	-0.091637647	normal	0.971224349	-0.202070549	normal	0.985480436	-0.050296284	normal	0.580166073	-0.118020433	normal	[R]	General function prediction only	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: metal ion binding (GO:0046872);; 	"K10645|0|hsa:57534|MIB1, DIP-1, DIP1, LVNC7, MIB, ZZANK2, ZZZ6; mindbomb E3 ubiquitin protein ligase 1; K10645 E3 ubiquitin-protein ligase mind-bomb [EC:6.3.2.19] (A)"	--	[R]	General function prediction only	"Ankyrin repeat;; Ankyrin repeats (3 copies);; Mib_herc2;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, ZZ type"	E3 ubiquitin-protein ligase MIB1 GN=MIB1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MIB1 [Eptesicus fuscus]
ENSG00000101773(RBBP8)	--	12.02656288	757	13.22425541	822	14.0853058	894	12.60628835	820	12.17914218	754	11.3113072	766	0.97373881	0.084333867	normal	0.96614702	-0.145720397	normal	0.943849786	-0.230799652	normal	0.687403217	-0.100964387	normal	--	--	Molecular Function: endonuclease activity (GO:0004519);; Biological Process: DNA repair (GO:0006281);; 	--	--	--	--	Tumour-suppressor protein CtIP N-terminal domain;; DNA repair protein endonuclease SAE2/CtIP C-terminus	DNA endonuclease RBBP8 GN=RBBP8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA endonuclease RBBP8 isoform X1 [Galeopterus variegatus] 
ENSG00000101782(RIOK3)	--	8.535950695	623	9.376956166	685	11.298509	771	13.04006824	933	11.22862855	796	15.25968847	1105	0.173894706	0.550696144	normal	0.954330564	0.19483856	normal	0.297236181	0.510112025	normal	0.069223045	0.426487603	normal	[TD]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning"	--	"K08872|0|hsa:8780|RIOK3, SUDD; RIO kinase 3 (EC:2.7.11.1); K08872 RIO kinase 3 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	RIO1 family;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase RIO3 GN=RIOK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase RIO3 isoform X1 [Physeter catodon]
ENSG00000101811(CSTF2)	--	13.13922279	761	12.16320832	759	14.32438849	817	16.6745894	1031	15.38792558	905	12.810327	789	0.69773435	0.406536228	normal	0.943293364	0.231967634	normal	0.975678352	-0.058492038	normal	0.325727267	0.199728388	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: mRNA 3'-end processing (GO:0031124);; 	"K14407|0|mcc:701235|CSTF2; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa; K14407 cleavage stimulation factor subunit 2 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"Hinge domain of cleavage stimulation factor subunit 2;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Transcription termination and cleavage factor C-terminal;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Cleavage stimulation factor subunit 2 GN=CSTF2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: cleavage stimulation factor subunit 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000101842(VSIG1)	--	0.018207209	1	0.036877146	2	0.072901356	3	0.163425733	9	0.210611221	11	0.033052531	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	V-set and immunoglobulin domain-containing protein 1 (Precursor) GN=VSIG1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: V-set and immunoglobulin domain-containing protein 1 isoform X2 [Equus przewalskii]
ENSG00000101843(PSMD10)	--	47.977479	1016	48.93781272	1049	52.92314181	1072	60.857355	1308	57.43338865	1198	52.4837957	1082	0.867573473	0.333184833	normal	0.967392767	0.16995727	normal	0.980456245	0.005096994	normal	0.388276341	0.172094523	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K06694|2.04617e-165|pps:100982434|PSMD10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; K06694 26S proteasome non-ATPase regulatory subunit 10 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	26S proteasome non-ATPase regulatory subunit 10 GN=PSMD10 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 10 isoform X1 [Tupaia chinensis]
ENSG00000101844(ATG4A)	--	4.827593171	188	4.511121888	160	4.228954536	162	7.339398875	286	6.148730644	245	5.813044955	219	0.356435234	0.570644534	normal	0.371288782	0.588755102	normal	0.800217083	0.423235324	normal	0.048207576	0.534282973	normal	--	--	--	"K08342|0|hsa:115201|ATG4A, APG4A, AUTL2; autophagy related 4A, cysteine peptidase; K08342 cysteine protease ATG4 [EC:3.4.22.-] (A)"	Regulation of autophagy (ko04140)	[ZU]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	Peptidase family C54	Cysteine protease ATG4A GN=ATG4A OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cysteine protease ATG4A isoform X1 [Ochotona princeps]
ENSG00000101846(STS)	--	1.707570872	205	2.082581	249	1.436356475	172	3.806644	457	2.685456	323	5.733076	691	1.56E-06	1.119973968	up	0.8522917	0.352079775	normal	0	1.988555575	up	0.045752977	1.212065154	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K01131|0|hsa:412|STS, ARSC, ARSC1, ASC, ES, SSDD, XLI; steroid sulfatase (microsomal), isozyme S (EC:3.1.6.2); K01131 steryl-sulfatase [EC:3.1.6.2] (A)"	Steroid hormone biosynthesis (ko00140)	[R]	General function prediction only	Sulfatase;; C-terminal region of aryl-sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	Steryl-sulfatase (Precursor) GN=STS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: steryl-sulfatase [Odobenus rosmarus divergens]
ENSG00000101849(TBL1X)	--	17.34343	1887	17.86077254	1617	18.77883563	1777	22.984451	2004	22.910918	1850	17.27635801	1839	0.985771636	0.055911645	normal	0.974081297	0.172628008	normal	0.985471909	0.041151929	normal	0.706162077	0.086966544	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K04508|0|hsa:6907|TBL1X, EBI, SMAP55, TBL1; transducin (beta)-like 1X-linked; K04508 transducin (beta)-like 1 (A)"	Wnt signaling pathway (ko04310)	[B]	Chromatin structure and dynamics	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A;; LisH"	F-box-like/WD repeat-containing protein TBL1X GN=TBL1X OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: F-box-like/WD repeat-containing protein TBL1X [Sarcophilus harrisii]
ENSG00000101850(GPR143)	--	0	0	0	0	0.244955134	2	0.317371297	8	0	0	0.084102706	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: dopamine binding (GO:0035240);; Molecular Function: L-DOPA binding (GO:0072544);; Molecular Function: tyrosine binding (GO:0072545);; 	"K08470|0|hsa:4935|GPR143, NYS6, OA1; G protein-coupled receptor 143; K08470 Ocular albinism type 1 protein (A)"	--	--	--	Ocular albinism type 1 protein;; 7 transmembrane receptor (Secretin family)	G-protein coupled receptor 143 GN=GPR143 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: G-protein coupled receptor 143 [Tupaia chinensis]
ENSG00000101856(PGRMC1)	--	104.02702	3055	110.383324	3240	107.353953	3137	125.65843	3715	114.371542	3361	124.386665	3663	0.968118894	0.251242842	normal	0.990451888	0.031455756	normal	0.977268457	0.215252611	normal	0.393478672	0.165931146	normal	--	--	--	K17278|5.03893e-127|pps:100992159|PGRMC1; progesterone receptor membrane component 1; K17278 membrane-associated progesterone receptor component (A)	--	[R]	General function prediction only	Cytochrome b5-like Heme/Steroid binding domain	Membrane-associated progesterone receptor component 1 GN=PGRMC1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: membrane-associated progesterone receptor component 1 [Odobenus rosmarus divergens]
ENSG00000101868(POLA1)	--	9.661185915	1092	9.389643146	1109	12.439421	1357	9.736145819	1149	11.96606618	1050	12.2024824	1116	0.980205926	0.042515362	normal	0.976107323	-0.100156208	normal	0.917742754	-0.290018137	normal	0.57584589	-0.122986537	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleoside binding (GO:0001882);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Biological Process: DNA replication (GO:0006260);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	"K02320|0|hsa:5422|POLA1, NSX, POLA, p180; polymerase (DNA directed), alpha 1, catalytic subunit (EC:2.7.7.7); K02320 DNA polymerase alpha subunit A [EC:2.7.7.7] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030)	[L]	"Replication, recombination and repair"	"DNA polymerase family B;; DNA polymerase family B, exonuclease domain;; DNA Polymerase alpha zinc finger;; DNA polymerase alpha subunit p180 N terminal"	DNA polymerase alpha catalytic subunit GN=POLA1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase alpha catalytic subunit [Ceratotherium simum simum]
ENSG00000101871(MID1)	--	84.49552803	5759	79.95870727	5771	90.04039759	5905	47.49985733	3426	63.09611187	4243	62.4634147	4234	0.000504116	-0.779852397	normal	0.650386853	-0.465020481	normal	0.517030954	-0.488058916	normal	9.96E-05	-0.571129128	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K08285|0|pps:100970390|MID1; midline 1; K08285 midline 1 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; B-box zinc finger;; Fibronectin type III domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase Midline-1 GN=MID1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase Midline-1 [Galeopterus variegatus]
ENSG00000101882(NKAP)	--	5.419359546	606	4.196936116	470	4.264777548	472	5.32718447	599	5.471242912	611	4.762736405	535	0.972722809	-0.047472989	normal	0.823102069	0.35607767	normal	0.955707146	0.171942833	normal	0.550674762	0.151164844	normal	--	--	"Molecular Function: chromatin binding (GO:0003682);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	--	--	[S]	Function unknown	Ras-induced vulval development antagonist	NF-kappa-B-activating protein GN=NKAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: NF-kappa-B-activating protein [Orcinus orca]
ENSG00000101883(RHOXF1)	--	0	0	0.0905489	1	0	0	0.0889062	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	--	--	[R]	General function prediction only	Homeobox domain	Rhox homeobox family member 1 GN=RHOXF1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: rhox homeobox family member 1 [Ceratotherium simum simum]
ENSG00000101888(NXT2)	--	13.45956003	380	13.57358193	391	13.99207027	419	11.836271	362	10.48149424	323	11.13258265	344	0.96437482	-0.100425893	normal	0.898042383	-0.295800067	normal	0.900655281	-0.291669325	normal	0.379999068	-0.230961727	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	K14285|5.18893e-133|ptr:473728|NXT2; nuclear transport factor 2-like export factor 2; K14285 NTF2-related export protein 1/2 (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Influenza A (ko05164)	[A]	RNA processing and modification	Nuclear transport factor 2 (NTF2) domain	NTF2-related export protein 2 GN=NXT2 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: NTF2-related export protein 2 isoform X1 [Myotis lucifugus]
ENSG00000101901(ALG13)	--	11.69594536	546	14.25851	593	13.53196658	510	15.23931209	558	15.03900142	552	15.2104604	625	0.972753594	0.000530431	normal	0.96501143	-0.12446132	normal	0.905731109	0.284304729	normal	0.874141821	0.052267998	normal	[S]	Function unknown	"Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K07432|0|pps:100990755|ALG13; ALG13, UDP-N-acetylglucosaminyltransferase subunit; K07432 beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141] (A)"	N-Glycan biosynthesis (ko00510)	--	--	Glycosyltransferase family 28 C-terminal domain;; OTU-like cysteine protease	Putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 GN=ALG13 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: LOW QUALITY PROTEIN: putative bifunctional UDP-N-acetylglucosamine transferase and deubiquitinase ALG13 isoform X1 [Bos taurus] 
ENSG00000101911(PRPS2)	--	47.00724964	1564	39.54320236	1366	42.21418862	1444	39.81690217	1444	47.12548561	1454	30.192329	1003	0.976159948	-0.145852858	normal	0.981459783	0.068569643	normal	0.207147943	-0.533366524	normal	0.489401947	-0.187239415	normal	[FE]	Nucleotide transport and metabolism;; Amino acid transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: ribose phosphate diphosphokinase activity (GO:0004749);; Biological Process: nucleoside metabolic process (GO:0009116);; Biological Process: nucleotide biosynthetic process (GO:0009165);; 	K00948|0|pps:100985585|PRPS2; phosphoribosyl pyrophosphate synthetase 2; K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] (A)	Pentose phosphate pathway (ko00030);; Purine metabolism (ko00230);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[FE]	Nucleotide transport and metabolism;; Amino acid transport and metabolism	N-terminal domain of ribose phosphate pyrophosphokinase;; Phosphoribosyl synthetase-associated domain;; Phosphoribosyl transferase domain	Ribose-phosphate pyrophosphokinase 2 GN=PRPS2 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: ribose-phosphate pyrophosphokinase 2 isoform X2 [Orycteropus afer afer]
ENSG00000101928(MOSPD1)	--	14.22786307	455	20.15222032	643	18.20225358	505	18.14949832	576	15.9363831	509	27.00477087	874	0.883144906	0.308442562	normal	0.819618507	-0.357631862	normal	0.001334844	0.781258254	normal	0.625739872	0.26916646	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	MSP (Major sperm protein) domain	Motile sperm domain-containing protein 1 GN=MOSPD1 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: motile sperm domain-containing protein 1 [Ceratotherium simum simum] 
ENSG00000101935(AMMECR1)	--	5.333512	399	6.827279028	484	4.7894808	334	8.467754	670	8.015129897	639	6.911604	547	0.010130475	0.714794271	normal	0.781572444	0.378350543	normal	0.019083458	0.700897009	normal	0.002186726	0.586581784	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	AMMECR1	AMME syndrome candidate gene 1 protein GN=AMMECR1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: AMME syndrome candidate gene 1 protein homolog isoform 1 [Trichechus manatus latirostris]
ENSG00000101938(CHRDL1)	--	0.020498591	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	von Willebrand factor type C domain	Chordin-like protein 1 (Precursor) GN=CHRDL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: chordin-like protein 1 [Odobenus rosmarus divergens]
ENSG00000101940(WDR13)	--	17.052915	775	21.29745836	883	16.13980433	756	21.38083039	1026	22.09091412	1029	22.36528092	1061	0.785998786	0.373285297	normal	0.957617834	0.199015097	normal	0.420738488	0.479861064	normal	0.04191393	0.346990487	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 13 GN=WDR13 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 13 [Physeter catodon]
ENSG00000101945(SUV39H1)	--	9.837578122	563	9.312633656	543	9.811855135	570	9.472210958	544	9.05833885	513	9.006143007	514	0.969859711	-0.080138028	normal	0.966617975	-0.103124389	normal	0.959713591	-0.157046011	normal	0.677559263	-0.11465183	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; 	K11419|0|pon:100172621|SUV39H1; suppressor of variegation 3-9 homolog 1 (Drosophila) (EC:2.1.1.43); K11419 histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43] (A)	Lysine degradation (ko00310)	[BK]	Chromatin structure and dynamics;; Transcription	SET domain;; Pre-SET motif;; Chromo (CHRromatin Organisation MOdifier) domain	Histone-lysine N-methyltransferase SUV39H1 GN=SUV39H1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SUV39H1 [Bos mutus]
ENSG00000101955(SRPX)	--	13.544044	477	10.917318	386	16.988854	594	19.142985	668	20.000362	701	17.48045	614	0.553340983	0.453786364	normal	0.000657463	0.836919711	normal	0.973163205	0.039385653	normal	0.045346948	0.423933031	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4174);; HYR domain;; Sushi domain (SCR repeat)	Sushi repeat-containing protein SRPX (Precursor) GN=SRPX OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: sushi repeat-containing protein SRPX, partial [Camelus dromedarius]"
ENSG00000101958(GLRA2)	--	0.03454409	1	0	0	0	0	0.018038077	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05194|0|hsa:2742|GLRA2, GLR; glycine receptor, alpha 2; K05194 glycine receptor alpha-2 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Glycine receptor subunit alpha-2 (Precursor) GN=GLRA2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: glycine receptor subunit alpha-2 isoform X2 [Equus caballus]
ENSG00000101966(XIAP)	--	14.41719507	1838	16.152673	2064	17.041319	1919	17.28252	2221	17.98303173	2224	18.10952829	2219	0.959469807	0.242056082	normal	0.985206561	0.086226389	normal	0.971789568	0.201116006	normal	0.359935209	0.173881	normal	--	--	--	"K04725|0|hsa:331|XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase; K04725 E3 ubiquitin-protein ligase XIAP (A)"	NF-kappa B signaling pathway (ko04064);; Ubiquitin mediated proteolysis (ko04120);; Apoptosis (ko04210);; Focal adhesion (ko04510);; Toxoplasmosis (ko05145);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	"Inhibitor of Apoptosis domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase XIAP GN=XIAP OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase XIAP [Camelus ferus] 
ENSG00000101972(STAG2)	--	41.58259846	2523	31.90986199	2791	39.3153685	2421	41.14767485	2711	38.11897097	2522	43.66597767	2942	0.987971974	0.072809866	normal	0.981054593	-0.167544853	normal	0.953739723	0.272747943	normal	0.816737675	0.058650649	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	K06671|0|ocu:100328701|STAG2; stromal antigen 2; K06671 cohesin complex subunit SA-1/2 (A)	Cell cycle (ko04110)	[D]	"Cell cycle control, cell division, chromosome partitioning"	STAG domain	Cohesin subunit SA-2 GN=STAG2 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cohesin subunit SA-2 isoform X1 [Equus przewalskii]
ENSG00000101974(ATP11C)	--	9.018908523	849	8.256782725	824	8.477139358	856	8.860710912	874	7.932031207	844	7.3180689	707	0.977761718	0.011016813	normal	0.976854832	0.013148261	normal	0.910820097	-0.283639752	normal	0.754282113	-0.082317686	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:286410|ATP11C, ATPIG, ATPIQ; ATPase, class VI, type 11C (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Phospholipid-transporting ATPase IG GN=ATP11C OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IG isoform X1 [Physeter catodon]
ENSG00000101977(MCF2)	--	0	0	0	0	0	0	0	0	0	0	0.028695033	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Divergent CRAL/TRIO domain	DBL-transforming protein GN=MCF2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: proto-oncogene DBL isoform X1 [Camelus ferus] 
ENSG00000101986(ABCD1)	--	6.2198145	305	3.666087132	211	5.25383087	242	2.673183287	145	3.584829	191	2.940147	148	2.77E-05	-1.095392275	down	0.954266504	-0.163861891	normal	0.095618172	-0.711954275	normal	0.016611382	-0.668216528	normal	--	--	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05675|0|hsa:215|ABCD1, ABC42, ALD, ALDP, AMN; ATP-binding cassette, sub-family D (ALD), member 1; K05675 ATP-binding cassette, subfamily D (ALD), member 1 (A)"	ABC transporters (ko02010);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	ABC transporter transmembrane region 2;; ABC transporter	ATP-binding cassette sub-family D member 1 GN=ABCD1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	ATP-binding cassette sub-family D member 1 [Oryctolagus cuniculus] 
ENSG00000101997(CCDC22)	--	7.98841	379	8.34624	400	8.44547	410	7.68673	365	7.84469	371	8.62163	411	0.965821314	-0.084783373	normal	0.96031055	-0.129498839	normal	0.970003325	-0.004759424	normal	0.83344726	-0.072640994	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF812)	Coiled-coil domain-containing protein 22 GN=CCDC22 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 22 [Camelus bactrianus]
ENSG00000102001(CACNA1F)	--	0.008570438	1	0.008426269	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04853|0|hsa:778|CACNA1F, AIED, COD3, COD4, CORDX, CORDX3, CSNB2, CSNB2A, CSNBX2, Cav1.4, Cav1.4alpha1, JM8, JMC8, OA2; calcium channel, voltage-dependent, L type, alpha 1F subunit; K04853 voltage-dependent calcium channel L type alpha-1F (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Retrograde endocannabinoid signaling (ko04723);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Oxytocin signaling pathway (ko04921);; Alzheimer's disease (ko05010);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Voltage gated calcium channel IQ domain;; Polycystin cation channel	Voltage-dependent L-type calcium channel subunit alpha-1F GN=CACNA1F OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent L-type calcium channel subunit alpha-1F isoform X1 [Sus scrofa]
ENSG00000102003(SYP)	--	3.102074795	127	2.57701	109	3.378329	119	0.6128961	25	0.74202123	32	0.988341028	40	4.66E-11	-2.305884642	down	3.28E-06	-1.742241223	down	2.04E-05	-1.545658287	down	2.16E-07	-1.891490763	down	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Membrane-associating domain	Synaptophysin GN=SYP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: synaptophysin [Ochotona princeps]
ENSG00000102007(PLP2)	--	179.238	3008	184.2819	3000	171.3226	2809	212.7623	3590	182.189	3019	201.7672	3377	0.974875341	0.224242066	normal	0.98993854	-0.012312115	normal	0.964018407	0.257267624	normal	0.42041232	0.158051317	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	Proteolipid protein 2 GN=PLP2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: proteolipid protein 2 [Galeopterus variegatus]
ENSG00000102010(BMX)	--	0.019871911	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K08896|0|hsa:660|BMX, ETK, PSCTK2, PSCTK3; BMX non-receptor tyrosine kinase (EC:2.7.10.2); K08896 cytoplasmic tyrosine-protein kinase BMX [EC:2.7.10.2] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; PH domain;; BTK motif	Cytoplasmic tyrosine-protein kinase BMX GN=BMX OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cytoplasmic tyrosine-protein kinase BMX [Ceratotherium simum simum]
ENSG00000102024(PLS3)	--	245.4883574	5772	440.4309203	6759	148.0029475	5917	251.8373109	8824	276.4229257	8319	430.8011962	8206	0.145697044	0.581403214	normal	0.976566813	0.278117569	normal	0.685407905	0.463420809	normal	0.00646247	0.436909702	normal	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	K17336|0|pps:100983224|PLS3; plastin 3; K17336 plastin-3 (A)	--	[Z]	Cytoskeleton	Calponin homology (CH) domain;; EF-hand domain pair;; EF hand;; EF hand;; CAMSAP CH domain;; EF-hand domain	Plastin-3 GN=PLS3 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: plastin-3 isoformX1 [Equus caballus] 
ENSG00000102030(NAA10)	--	62.50756561	1274	52.46121162	1208	55.31465431	1243	60.66089844	1329	57.34881555	1276	49.45985981	1044	0.982224696	0.030108013	normal	0.980456077	0.057511261	normal	0.936525179	-0.259650865	normal	0.84882597	-0.051589286	normal	[R]	General function prediction only	"Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	"K00670|1.00083e-167|ptr:741472|NAA10; N(alpha)-acetyltransferase 10, NatA catalytic subunit; K00670 peptide alpha-N-acetyltransferase [EC:2.3.1.88] (A)"	--	[R]	General function prediction only	Acetyltransferase (GNAT) family;; FR47-like protein;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain	N-alpha-acetyltransferase 10 GN=NAA10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: N-alpha-acetyltransferase 10 isoform X3 [Mustela putorius furo] 
ENSG00000102034(ELF4)	--	12.317049	1105	10.894478	968	11.42812454	1032	14.45116057	1304	14.68502472	1340	11.47910744	1041	0.959537303	0.207799041	normal	0.576171686	0.44713141	normal	0.98002207	0.004229485	normal	0.220258943	0.225320309	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09428|0|hsa:2000|ELF4, ELFR, MEF; E74-like factor 4 (ets domain transcription factor); K09428 E74-like factor 1/2/4 (A)"	--	[K]	Transcription	Transcription factor protein N terminal;; Ets-domain	ETS-related transcription factor Elf-4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ETS-related transcription factor Elf-4 [Ceratotherium simum simum]
ENSG00000102038(SMARCA1)	--	39.26584	3143	36.20487496	2878	38.66377528	3061	28.5798457	2309	34.24950147	2712	30.1448317	2399	0.492310076	-0.475433985	normal	0.986752235	-0.107077997	normal	0.872790475	-0.359660095	normal	0.051920684	-0.31254398	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Biological Process: chromatin remodeling (GO:0006338);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; Molecular Function: nucleosome binding (GO:0031491);; Biological Process: ATP-dependent chromatin remodeling (GO:0043044);; "	K11727|0|mcf:101865868|uncharacterized LOC101865868; K11727 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1 [EC:3.6.4.-] (A)	--	[K]	Transcription	"SNF2 family N-terminal domain;; SLIDE;; HAND;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; Class II histone deacetylase complex subunits 2 and 3;; DEAD/DEAH box helicase;; DNA-binding domain"	Probable global transcription activator SNF2L1 GN=SMARCA1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: probable global transcription activator SNF2L1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000102043(MTMR8)	--	1.018469169	38	0.75865969	26	1.291992938	44	0.949547625	39	0.746222449	24	0.947578908	36	0.982345306	0.006387518	normal	0.985248344	-0.12908649	normal	0.9742931	-0.28687941	normal	0.881309871	-0.146530258	normal	--	--	--	K18083|0|hsa:55613|MTMR8; myotubularin related protein 8 (EC:3.1.3.-); K18083 myotubularin-related protein 6/7/8 [EC:3.1.3.-] (A)	--	[R]	General function prediction only	Myotubularin-like phosphatase domain	Myotubularin-related protein 8 GN=MTMR8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: myotubularin-related protein 8 [Ceratotherium simum simum]
ENSG00000102048(ASB9)	--	9.50480419	394	11.26493205	484	10.7023451	406	11.00291911	406	10.27459705	377	11.4402281	466	0.96962449	0.012404184	normal	0.786548921	-0.380518057	normal	0.94984786	0.189898075	normal	0.862636741	-0.060868632	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10331|0|hsa:140462|ASB9; ankyrin repeat and SOCS box containing 9; K10331 ankyrin repeat and SOCS box protein 9 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 9 GN=ASB9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 9 [Camelus ferus] 
ENSG00000102053(ZC3H12B)	--	0.326128261	39	0.159465674	19	0.367607817	43	0.292457394	35	0.532141	54	0.311327	30	0.980560549	-0.17948288	normal	0.054539305	1.41597395	normal	0.95540143	-0.50624079	normal	0.809168413	0.216175459	normal	--	--	--	"K18668|0|hsa:340554|ZC3H12B, CXorf32, MCPIP2; zinc finger CCCH-type containing 12B; K18668 ribonuclease ZC3H12 [EC:3.1.-.-] (A)"	--	[S]	Function unknown	Zc3h12a-like Ribonuclease NYN domain	Probable ribonuclease ZC3H12B GN=ZC3H12B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: probable ribonuclease ZC3H12B [Oryctolagus cuniculus] 
ENSG00000102054(RBBP7)	--	113.0755781	4308	110.558785	4349	111.322948	4180	112.687986	4295	104.677194	3977	101.7178762	3852	0.992416151	-0.035179816	normal	0.987699918	-0.150375	normal	0.989152822	-0.126139127	normal	0.643745166	-0.104037878	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11659|0|pps:100975672|RBBP7; retinoblastoma binding protein 7; K11659 histone-binding protein RBBP7 (A)	--	[B]	Chromatin structure and dynamics	"WD domain, G-beta repeat;; Histone-binding protein RBBP4 or subunit C of CAF1 complex;; Eukaryotic translation initiation factor eIF2A"	Histone-binding protein RBBP7 GN=RBBP7 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone-binding protein RBBP7 isoform X1 [Mustela putorius furo] 
ENSG00000102057(KCND1)	--	1.651237317	144	1.658341002	134	1.6571347	145	1.320272161	113	1.3187429	122	2.6964526	155	0.896004588	-0.376036377	normal	0.959993787	-0.154944928	normal	0.965413037	0.087045668	normal	0.782702731	-0.137336144	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04891|0|pps:100983577|KCND1; potassium voltage-gated channel, Shal-related subfamily, member 1; K04891 potassium voltage-gated channel Shal-related subfamily D member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Domain of unknown function (DUF3399);; Ion transport protein;; BTB/POZ domain;; Shal-type voltage-gated potassium channels;; Ion channel;; Polycystin cation channel	Potassium voltage-gated channel subfamily D member 1 GN=KCND1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily D member 1 isoform X1 [Canis lupus familiaris]
ENSG00000102078(SLC25A14)	--	10.05712246	195	12.5762607	222	13.3887257	247	9.318587485	180	9.745864146	195	11.04096379	204	0.958772026	-0.145118909	normal	0.945290801	-0.207006248	normal	0.918030928	-0.282328238	normal	0.537441749	-0.218131096	normal	--	--	--	"K15106|0|pps:100992888|SLC25A14; solute carrier family 25 (mitochondrial carrier, brain), member 14; K15106 solute carrier family 25 (mitochondrial carrier), member 14/30 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Brain mitochondrial carrier protein 1 GN=SLC25A14 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	Brain mitochondrial carrier protein 1 [Bos mutus]
ENSG00000102081(FMR1)	--	15.27006603	1045	17.0831176	1216	17.20885335	1215	17.41391004	1226	15.16862614	1043	17.09697031	1196	0.960850522	0.199352962	normal	0.945355803	-0.242504608	normal	0.981404516	-0.030991486	normal	0.933478685	-0.025809522	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K15516|0|ptr:465894|FMR1; fragile X mental retardation 1; K15516 fragile X mental retardation protein (A)	RNA transport (ko03013)	--	--	Fragile X-related 1 protein C terminal;; KH domain;; Agenet domain;; KH domain	Fragile X mental retardation protein 1 GN=FMR1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: fragile X mental retardation protein 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000102096(PIM2)	--	10.80933884	362	8.668619498	271	10.12944841	334	10.7789366	352	9.648002692	320	8.617493709	275	0.966562633	-0.070941167	normal	0.939747648	0.217235876	normal	0.907527025	-0.287272093	normal	0.899311644	-0.051914877	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08806|0|ptr:473600|PIM2; Pim-2 proto-oncogene, serine/threonine kinase; K08806 proto-oncogene serine/threonine-protein kinase Pim-2 [EC:2.7.11.1] (A)"	Acute myeloid leukemia (ko05221)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase pim-2 GN=PIM2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	OTU domain-containing protein 5 [Tupaia chinensis]
ENSG00000102098(SCML2)	--	5.278756946	324	5.201684053	355	4.822334773	310	4.72935224	306	5.058143519	312	5.398253876	321	0.962145812	-0.112744157	normal	0.942869154	-0.206759249	normal	0.96739206	0.04181318	normal	0.787978426	-0.096065761	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K11465|0|hsa:10389|SCML2; sex comb on midleg-like 2 (Drosophila); K11465 sex comb on midleg-like protein 2 (A)	--	[K]	Transcription	mbt repeat;; Protein of unknown function (DUF3588);; SAM domain (Sterile alpha motif);; Sterile alpha motif (SAM)/Pointed domain	Sex comb on midleg-like protein 2 GN=SCML2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: sex comb on midleg-like protein 2 [Equus caballus]
ENSG00000102100(SLC35A2)	--	36.20504512	1022	36.90363675	1078	37.95070508	1026	42.33177586	1144	41.340555	1174	44.53011242	1248	0.973221005	0.131672434	normal	0.976539464	0.101512187	normal	0.927366935	0.273929119	normal	0.401740807	0.16900996	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15272|0|myb:102258949|SLC35A2; solute carrier family 35 (UDP-galactose transporter), member A2; K15272 solute carrier family 35 (UDP-sugar transporter), member A1/2/3 (A)"	--	[G]	Carbohydrate transport and metabolism	Nucleotide-sugar transporter;; UAA transporter family;; Multidrug resistance efflux transporter;; EamA-like transporter family	UDP-galactose translocator GN=SLC35A2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-galactose translocator isoform X1 [Orycteropus afer afer]
ENSG00000102103(PQBP1)	--	30.4608577	598	35.58914878	696	33.5207444	700	40.98977901	802	35.90057918	706	36.71276791	719	0.739616498	0.391752703	normal	0.97485239	-0.00084386	normal	0.97526401	0.030280857	normal	0.565071937	0.137985113	normal	--	--	--	K12865|2.81059e-149|ptr:739437|PQBP1; polyglutamine binding protein 1; K12865 polyglutamine-binding protein 1 (A)	Spliceosome (ko03040)	[K]	Transcription	WW domain	Polyglutamine-binding protein 1 GN=PQBP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	polyglutamine-binding protein 1 [Sus scrofa] 
ENSG00000102104(RS1)	--	0	0	0	0	0	0	0.019327	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	F5/8 type C domain	Retinoschisin (Precursor) GN=RS1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: retinoschisin [Tupaia chinensis]
ENSG00000102109(PCSK1N)	--	66.6254	816	62.9636	800	59.3184	774	66.7613	834	67.9401	844	64.9989	810	0.977303099	0.000644767	normal	0.975493607	0.0557139	normal	0.975573266	0.057187667	normal	0.903323627	0.036643916	normal	--	--	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Biological Process: negative regulation of endopeptidase activity (GO:0010951);; 	--	--	--	--	ProSAAS precursor	Big LEN (Precursor) GN=PCSK1N OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: proSAAS [Condylura cristata]
ENSG00000102119(EMD)	--	54.92529	1043	52.66141	994	54.36748	1032	67.69368	1287	67.65773	1270	56.37089	1045	0.929003779	0.272079298	normal	0.872722266	0.331636833	normal	0.980016054	0.009754325	normal	0.265375946	0.209305777	normal	--	--	--	"K12569|4.15816e-138|hsa:2010|EMD, EDMD, LEMD5, STA; emerin; K12569 emerin (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	--	--	LEM domain	Emerin GN=EMD OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: emerin [Lipotes vexillifer]
ENSG00000102125(TAZ)	--	22.487076	673	21.601065	624	16.490781	499	15.5397935	472	16.64801672	509	19.072859	586	0.23000333	-0.541168029	normal	0.878453917	-0.314461459	normal	0.94068689	0.222945293	normal	0.399463159	-0.21774873	normal	--	--	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13511|0|hsa:6901|TAZ, BTHS, CMD3A, EFE, EFE2, G4.5, LVNCX, Taz1; tafazzin; K13511 monolysocardiolipin acyltransferase [EC:2.3.1.-] (A)"	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	Tafazzin GN=TAZ OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: tafazzin isoform 3 [Ovis aries]
ENSG00000102128(RAB40AL)	--	0.0632663	1	0.18253	3	0.240449	3	0.185513	3	0.367043	5	0.124486	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K07928|0|hsa:282808|RAB40AL, MRXSMP, RAR2, RLGP; RAB40A, member RAS oncogene family-like; K07928 Ras-related protein Rab-40 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; SOCS box;; ADP-ribosylation factor family	Ras-related protein Rab-40A-like GN=RAB40AL OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-40B isoform 1 [Odobenus rosmarus divergens]
ENSG00000102144(PGK1)	--	293.7367498	23334	256.7449646	20467	267.5683647	20997	321.968396	25743	196.6333305	15518	283.8219886	22541	0.997726239	0.110907332	normal	0.914236286	-0.420747749	normal	0.997630416	0.094070324	normal	0.928754815	-0.044241214	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: phosphoglycerate kinase activity (GO:0004618);; Biological Process: glycolytic process (GO:0006096);; 	K00927|0|ptr:473678|PGK1; phosphoglycerate kinase 1 (EC:2.7.2.3); K00927 phosphoglycerate kinase [EC:2.7.2.3] (A)	Glycolysis / Gluconeogenesis (ko00010);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Phosphoglycerate kinase	Phosphoglycerate kinase 1 GN=PGK1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: phosphoglycerate kinase 1-like [Myotis davidii]
ENSG00000102145(GATA1)	--	0	0	0	0	0	0	0	0	0	0	0.0366345	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09182|0|hsa:2623|GATA1, ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT; GATA binding protein 1 (globin transcription factor 1); K09182 GATA-binding protein 1 (A)"	--	[K]	Transcription	GATA zinc finger	Erythroid transcription factor GN=GATA1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: erythroid transcription factor [Trichechus manatus latirostris]
ENSG00000102158(MAGT1)	--	31.178401	1831	33.2427	2028	32.6004	1925	43.63106	2616	39.11215	2287	41.90345	2558	0.433914975	0.483557436	normal	0.980155279	0.151865468	normal	0.765070319	0.401591806	normal	0.027479766	0.345959964	normal	--	--	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	OST3 / OST6 family;; Thioredoxin	Magnesium transporter protein 1 (Precursor) GN=MAGT1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: magnesium transporter protein 1 [Equus caballus]
ENSG00000102172(SMS)	--	101.4870798	3131	103.6714	3245	107.6000613	3290	167.9008244	5212	134.17078	4097	121.8539622	3745	0.004941662	0.704110853	normal	0.940628426	0.314792039	normal	0.983425977	0.178509736	normal	0.051314941	0.411291535	normal	--	--	--	K00802|0|pps:100974711|spermine synthase; K00802 spermine synthase [EC:2.5.1.22] (A)	Cysteine and methionine metabolism (ko00270);; Arginine and proline metabolism (ko00330);; beta-Alanine metabolism (ko00410);; Glutathione metabolism (ko00480)	[E]	Amino acid transport and metabolism	Spermine/spermidine synthase	Spermine synthase GN=SMS OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	spermine synthase [Bos taurus] 
ENSG00000102174(PHEX)	--	0.469159592	34	0.803652409	53	0.38578203	29	1.377440392	93	1.90914342	129	1.650975694	113	0.00189587	1.381655297	up	0.001028831	1.238527041	up	2.32E-07	1.900008922	up	4.66E-05	1.508740679	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08636|0|hsa:5251|PHEX, HPDR, HPDR1, HYP, HYP1, LXHR, PEX, XLH; phosphate regulating endopeptidase homolog, X-linked; K08636 phosphate-regulating neutral endopeptidase [EC:3.4.24.-] (A)"	--	[E]	Amino acid transport and metabolism	Peptidase family M13;; Peptidase family M13	Phosphate-regulating neutral endopeptidase GN=PHEX OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: phosphate-regulating neutral endopeptidase [Tupaia chinensis]
ENSG00000102178(UBL4A)	--	27.33678278	1288	24.1842743	1147	27.03922286	1299	30.445286	1438	29.86119806	1396	25.14659227	1177	0.976908641	0.127954321	normal	0.938726122	0.261693817	normal	0.972695565	-0.150394531	normal	0.731247178	0.081632791	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	--	--	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like	Ubiquitin-like protein 4A GN=UBL4A OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	ubiquitin-like protein 4A [Oryctolagus cuniculus] 
ENSG00000102181(CD99L2)	--	84.00091779	5697	70.59019911	4793	74.48989759	4995	62.13129165	4166	62.85430289	4250	70.42597613	4685	0.541116326	-0.482219044	normal	0.984317431	-0.194827328	normal	0.991658347	-0.100695587	normal	0.133670677	-0.262085839	normal	--	--	--	--	--	--	--	CD99 antigen like protein 2	CD99 antigen-like protein 2 (Precursor) GN=CD99L2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CD99 antigen-like protein 2 isoform 1 [Orcinus orca]
ENSG00000102189(EEA1)	--	4.32644713	674	5.256675283	935	5.531764992	939	10.01775193	1827	8.036575601	1420	10.88981612	1890	2.23E-14	1.405799577	up	0.103447136	0.580658879	normal	4.46E-07	0.999739989	normal	7.61E-06	0.990580114	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K12478|0|hsa:8411|EEA1, MST105, MSTP105, ZFYVE2; early endosome antigen 1; K12478 early endosome antigen 1 (A)"	Endocytosis (ko04144);; Phagosome (ko04145);; Tuberculosis (ko05152)	--	--	FYVE zinc finger	Early endosome antigen 1 GN=EEA1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: early endosome antigen 1 [Odobenus rosmarus divergens]
ENSG00000102195(GPR50)	--	0.0306239	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04287|0|hsa:9248|GPR50, H9, Mel1c; G protein-coupled receptor 50; K04287 G protein-coupled receptor 50 (A)"	Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Melatonin-related receptor GN=GPR50 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: melatonin-related receptor [Odobenus rosmarus divergens]
ENSG00000102218(RP2)	--	6.38117	322	6.63935	335	7.15509	355	12.3071	630	10.4107	526	9.18531	465	5.58E-05	0.934216133	normal	0.088053902	0.62719781	normal	0.7878742	0.379702861	normal	0.000450933	0.657669561	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	"K18272|0|hsa:6102|RP2, DELXp11.3, NM23-H10, NME10, TBCCD2, XRP2; retinitis pigmentosa 2 (X-linked recessive); K18272 protein XRP2 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin binding cofactor C;; Adenylate cyclase associated (CAP) C terminal	Protein XRP2 GN=RP2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein XRP2 [Pteropus alecto] 
ENSG00000102221(JADE3)	--	7.314533407	574	6.322738831	483	6.371006	550	10.47324301	675	7.269481455	638	6.704004831	551	0.949631681	0.202504254	normal	0.780130618	0.379071038	normal	0.972818645	-0.005655206	normal	0.404946234	0.192364962	normal	--	--	--	--	--	[R]	General function prediction only	PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; Enhancer of polycomb-like;; PHD-finger;; PHD-finger	Protein Jade-3 GN=JADE3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein Jade-3 [Physeter catodon]
ENSG00000102225(CDK16)	--	44.6207297	2398	41.63054974	2108	41.57404105	2380	37.56057914	2162	39.7136465	2272	33.13338261	1883	0.977315662	-0.180175745	normal	0.985404664	0.086601559	normal	0.878844941	-0.345972273	normal	0.469077809	-0.145831561	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08820|0|hsa:5127|CDK16, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1; cyclin-dependent kinase 16 (EC:2.7.11.22); K08820 cyclin-dependent kinase 16 [EC:2.7.11.22] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Cyclin-dependent kinase 16 GN=CDK16 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cyclin-dependent kinase 16 isoform X2 [Mustela putorius furo] 
ENSG00000102226(USP11)	--	33.45009338	2314	31.69161019	2216	33.63414246	2363	25.1732031	1742	27.9152862	1898	31.76023392	2120	0.619324107	-0.440138386	normal	0.959198961	-0.244723776	normal	0.979342012	-0.16473544	normal	0.090456177	-0.279569607	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11835|0|hsa:8237|USP11, UHX1; ubiquitin specific peptidase 11 (EC:3.4.19.12); K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; DUSP domain;; Ubiquitin-like domain	Ubiquitin carboxyl-terminal hydrolase 11 GN=USP11 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 11 isoform X2 [Galeopterus variegatus]
ENSG00000102241(HTATSF1)	--	24.04823465	1440	22.30063657	1390	24.07477154	1498	23.07546	1346	24.55242235	1494	17.21355401	1075	0.977216184	-0.128081273	normal	0.980993702	0.082582034	normal	0.390211348	-0.486409994	normal	0.420455992	-0.166289016	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13093|0|hsa:27336|HTATSF1, TAT-SF1, TATSF1, dJ196E23.2; HIV-1 Tat specific factor 1; K13093 HIV Tat-specific factor 1 (A)"	--	[K]	Transcription	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	HIV Tat-specific factor 1 GN=HTATSF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: HIV Tat-specific factor 1 homolog [Odobenus rosmarus divergens]
ENSG00000102265(TIMP1)	--	160.074079	1902	155.181111	1876	158.6559977	1958	162.152187	1996	158.848831	1875	160.977232	1947	0.986235725	0.038731669	normal	0.985791544	-0.022177907	normal	0.986597351	-0.016406615	normal	1	-0.000740829	normal	--	--	Molecular Function: metalloendopeptidase inhibitor activity (GO:0008191);; 	K16451|6.56322e-139|pps:100990914|TIMP1; TIMP metallopeptidase inhibitor 1; K16451 metallopeptidase inhibitor 1 (A)	HIF-1 signaling pathway (ko04066)	[R]	General function prediction only	Tissue inhibitor of metalloproteinase	Metalloproteinase inhibitor 1 (Precursor) GN=TIMP1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	metalloproteinase inhibitor 1 precursor [Bos taurus] 
ENSG00000102271(KLHL4)	--	2.20242616	157	1.677447	123	2.963577	164	4.03474577	296	3.400294487	233	2.5800869	162	0.003502242	0.877648464	normal	0.007846347	0.892148029	normal	0.967260354	-0.025754491	normal	0.148028225	0.615509887	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10442|0|mcf:101925929|hypothetical protein; K10442 kelch-like protein 1/4/5 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Kelch-like protein 4 GN=KLHL4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 4-like [Vicugna pacos]
ENSG00000102287(GABRE)	--	13.20623157	1366	8.608891711	983	11.9948071	1329	8.323399244	905	12.90902597	1372	9.058607189	981	0.036323608	-0.623931153	normal	0.528913034	0.458990392	normal	0.562619098	-0.445714827	normal	0.642689264	-0.195417944	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05185|0|hsa:2564|GABRE; gamma-aminobutyric acid (GABA) A receptor, epsilon; K05185 gamma-aminobutyric acid receptor subunit epsilon (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Gamma-aminobutyric acid receptor subunit epsilon (Precursor) GN=GABRE OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit epsilon [Galeopterus variegatus]
ENSG00000102302(FGD1)	--	7.19141	632	6.73044	591	7.26437	647	6.74698	588	6.86775	601	5.19189	459	0.964894111	-0.134601306	normal	0.972965699	0.002773266	normal	0.374021037	-0.502162418	normal	0.369456779	-0.204038324	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Molecular Function: metal ion binding (GO:0046872);; 	"K05720|0|hsa:2245|FGD1, AAS, FGDY, MRXS16, ZFYVE3; FYVE, RhoGEF and PH domain containing 1; K05720 FYVE, RhoGEF and PH domain containing 1 (A)"	Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; FYVE zinc finger	"FYVE, RhoGEF and PH domain-containing protein 1 GN=FGD1 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: FYVE, RhoGEF and PH domain-containing protein 1 [Leptonychotes weddellii]"
ENSG00000102309(PIN4)	--	19.30869	392	19.7423254	401	20.587935	406	23.765257	484	21.671818	437	16.3464764	328	0.913202511	0.272359024	normal	0.964347789	0.102235082	normal	0.881568567	-0.314768326	normal	0.921405102	0.03668679	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: isomerase activity (GO:0016853);; 	"K09579|3.27229e-80|pps:100990176|PIN4; protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin); K09579 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	PPIC-type PPIASE domain;; PPIC-type PPIASE domain	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 GN=PIN4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [Pteropus alecto] 
ENSG00000102312(PORCN)	--	9.538759514	238	5.951656058	148	8.47786	215	20.51228575	503	19.21438593	473	19.327141	486	7.31E-06	1.044026765	up	1.61E-13	1.644897323	up	3.06E-07	1.16274005	up	4.54E-11	1.261484146	up	[S]	Function unknown	--	K00181|0|mcf:102125855|PORCN; porcupine homolog (Drosophila); K00181 porcupine (A)	Wnt signaling pathway (ko04310)	[R]	General function prediction only	"MBOAT, membrane-bound O-acyltransferase family"	Protein-cysteine N-palmitoyltransferase porcupine GN=PORCN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein-cysteine N-palmitoyltransferase porcupine isoform X1 [Echinops telfairi]
ENSG00000102313(ITIH6)	--	0.0285827	3	0.0484233	5	0.00947679	0	0	0	0.0092624	0	0.0660485	7	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Biological Process: hyaluronan metabolic process (GO:0030212);; 	--	--	--	--	Vault protein inter-alpha-trypsin domain;; Inter-alpha-trypsin inhibitor heavy chain C-terminus;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Inter-alpha-trypsin inhibitor heavy chain H6 (Precursor) GN=ITIH6 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: inter-alpha-trypsin inhibitor heavy chain H6 [Eptesicus fuscus]
ENSG00000102316(MAGED2)	--	42.57396082	1877	39.46417266	1758	37.29397326	1653	40.2803084	1784	47.08279929	2084	39.94793682	1756	0.98278102	-0.104057912	normal	0.964524666	0.223816641	normal	0.983504096	0.078844684	normal	0.782747644	0.067574737	normal	--	--	--	--	--	[S]	Function unknown	MAGE family	Melanoma-associated antigen D2 GN=MAGED2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: melanoma-associated antigen D2 isoform X1 [Oryctolagus cuniculus] 
ENSG00000102317(RBM3)	--	98.73825838	3073	97.87324357	3191	89.04484884	2651	155.854023	4884	125.205029	3868	99.78423301	3055	0.029197517	0.637328357	normal	0.967823325	0.256042272	normal	0.978033365	0.196239905	normal	0.241963185	0.382419671	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13186|3.80745e-59|nle:100595916|RBM3; RNA binding motif (RNP1, RRM) protein 3; K13186 RNA-binding protein 3 (A)"	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Putative RNA-binding protein 3 GN=RBM3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: putative RNA-binding protein 3 isoform 1 [Equus caballus] 
ENSG00000102349(KLF8)	--	0	0	0	0	0	0	0.032451156	2	0	0	0.013222696	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09205|0|ptr:465661|KLF8; Kruppel-like factor 8; K09205 krueppel-like factor 8/12 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 8 GN=KLF8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: Krueppel-like factor 8 isoform X1 [Oryctolagus cuniculus]
ENSG00000102359(SRPX2)	--	1.656562	118	1.255418	123	1.59441	92	2.845023008	196	2.7600943	225	2.00033	147	0.199725984	0.694153939	normal	0.020004295	0.842076267	normal	0.4334655	0.659172261	normal	0.011976483	0.74806502	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4174);; HYR domain;; Sushi domain (SCR repeat)	Sushi repeat-containing protein SRPX2 (Precursor) GN=SRPX2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sushi repeat-containing protein SRPX2 [Ursus maritimus] 
ENSG00000102362(SYTL4)	--	3.133542968	246	3.20130102	255	3.203835321	248	2.810111171	219	3.116069687	242	2.364886	183	0.947898327	-0.197253014	normal	0.962110112	-0.09633023	normal	0.742609421	-0.443626304	normal	0.462672814	-0.239532505	normal	--	--	--	K17598|0|pps:100985840|SYTL4; synaptotagmin-like 4; K17598 synaptotagmin-like protein (A)	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; FYVE-type zinc finger	Synaptotagmin-like protein 4 GN=SYTL4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-like protein 4 [Ailuropoda melanoleuca] 
ENSG00000102383(ZDHHC15)	--	0	0	0	0	0	0	0	0	0.010785384	0	0.0110576	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18932|0|pps:100982144|ZDHHC15; zinc finger, DHHC-type containing 15; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC15 GN=ZDHHC15 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC15 isoform X1 [Condylura cristata]
ENSG00000102384(CENPI)	--	13.68991345	849	15.70295529	955	19.95045094	967	12.83947589	802	10.23346714	557	11.9084574	648	0.971713715	-0.112784531	normal	0.000939864	-0.79757509	normal	0.095609105	-0.584688849	normal	0.00489587	-0.487277394	normal	--	--	Cellular Component: kinetochore (GO:0000776);; Biological Process: centromere complex assembly (GO:0034508);; 	"K11501|0|hsa:2491|CENPI, CENP-I, FSHPRH1, LRPR1, Mis6; centromere protein I; K11501 centromere protein I (A)"	--	--	--	Mis6	Centromere protein I GN=CENPI OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centromere protein I [Equus caballus]
ENSG00000102385(DRP2)	--	0.264418422	36	0.229735146	31	0.304371426	40	0.278234251	37	0.248515451	33	0.17869964	24	0.982970681	0.00834481	normal	0.98295852	0.065666228	normal	0.918935843	-0.710240831	normal	0.815579992	-0.208935624	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[NTZ]	Cell motility;; Signal transduction mechanisms;; Cytoskeleton	"EF hand;; EF-hand;; Zinc finger, ZZ type;; Spectrin repeat;; WW domain"	Dystrophin-related protein 2 GN=DRP2 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: dystrophin-related protein 2 isoform 1 [Equus caballus]
ENSG00000102387(TAF7L)	--	0.057302718	2	0.0513132	2	0.025574862	0	0.028215165	1	0.056055701	1	0.051011312	2	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Cellular Component: transcription factor TFIID complex (GO:0005669);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	"K03132|0|pps:100992137|TAF7L; TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa; K03132 transcription initiation factor TFIID subunit 7 (A)"	Basal transcription factors (ko03022)	[K]	Transcription	TAFII55 protein conserved region	Transcription initiation factor TFIID subunit 7-like GN=TAF7L OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 7-like [Ailuropoda melanoleuca]
ENSG00000102390(PBDC1)	--	11.849763	308	14.94448	391	13.03569	333	15.60929	407	14.795305	382	15.73944	409	0.813462102	0.369657697	normal	0.967265786	-0.054808054	normal	0.904413719	0.287108772	normal	0.486792329	0.193846793	normal	--	--	--	--	--	[S]	Function unknown	Polysaccharide biosynthesis	Protein PBDC1 GN=PBDC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein PBDC1-like [Camelus ferus]
ENSG00000102393(GLA)	--	60.6983	1215	73.8611	1478	67.139	1335	61.0278	1237	58.3048	1161	72.2651	1452	0.981858931	-0.00493689	normal	0.816846618	-0.369277383	normal	0.978786162	0.112787728	normal	0.726178609	-0.086005578	normal	--	--	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Molecular Function: alpha-galactosidase activity (GO:0004557);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K01189|0|hsa:2717|GLA, GALA; galactosidase, alpha (EC:3.2.1.22); K01189 alpha-galactosidase [EC:3.2.1.22] (A)"	Galactose metabolism (ko00052);; Glycerolipid metabolism (ko00561);; Sphingolipid metabolism (ko00600);; Glycosphingolipid biosynthesis - globo series (ko00603);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	Melibiase	Alpha-galactosidase A (Precursor) GN=GLA OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: alpha-galactosidase A [Galeopterus variegatus]
ENSG00000102401(ARMCX3)	--	20.28402317	1018	23.26247512	1123	22.27796305	1092	21.94343422	1092	20.73462741	990	23.72010935	1136	0.978298626	0.07030058	normal	0.958390819	-0.202992679	normal	0.980000134	0.048632501	normal	0.926676359	-0.027810696	normal	--	--	--	--	--	--	--	Armadillo-like	Armadillo repeat-containing X-linked protein 3 GN=ARMCX3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing X-linked protein 3 [Physeter catodon]
ENSG00000102409(BEX4)	--	2.98565681	57	2.31972201	44	2.433508299	45	1.3842294	28	2.667655761	48	1.339358891	26	0.429566678	-1.016463979	normal	0.977797293	0.10078714	normal	0.872469808	-0.765464555	normal	0.374689715	-0.538602303	normal	--	--	--	--	--	--	--	Brain expressed X-linked like family	Protein BEX4 GN=BEX4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein BEX4 [Tupaia chinensis] 
ENSG00000102445(RUBCNL)	--	0	0	0	0	0	0	0	0	0	0	0.506595025	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4206)	Uncharacterized protein KIAA0226-like GN=KIAA0226L OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: uncharacterized protein KIAA0226-like homolog isoform X1 [Equus caballus] 
ENSG00000102452(NALCN)	--	6.2775382	408	6.0773905	381	7.125150005	497	7.600728545	578	6.06544592	488	7.065059987	463	0.511237631	0.470173952	normal	0.857263896	0.334487874	normal	0.965617797	-0.110177674	normal	0.339702192	0.228233044	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Polycystin cation channel	Sodium leak channel non-selective protein GN=NALCN OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium leak channel non-selective protein [Ceratotherium simum simum]
ENSG00000102466(FGF14)	--	0.021208898	4	0.005341111	1	0.010710306	1	0.042051655	8	0.046100654	8	0.010501292	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|0|nle:100593119|FGF14; fibroblast growth factor 14; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 14 GN=FGF14 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 14-like isoform X1 [Elephantulus edwardii] 
ENSG00000102471(NDFIP2)	--	22.70918076	629	23.16287275	642	25.03144878	697	28.774162	790	26.99757297	726	29.37098844	822	0.896617907	0.297311226	normal	0.9623293	0.155624806	normal	0.942893586	0.229229828	normal	0.267079679	0.227598137	normal	--	--	--	--	--	[R]	General function prediction only	Protein of unknown function (DUF2370)	NEDD4 family-interacting protein 2 GN=NDFIP2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: NEDD4 family-interacting protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000102524(TNFSF13B)	--	0.686281624	14	0.304654422	12	0.282138635	4	0.626126882	25	0.387413	15	0.175023641	7	0.964278799	0.743902696	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	"K05476|3.19639e-175|ptr:467323|TNFSF13B; tumor necrosis factor (ligand) superfamily, member 13b; K05476 tumor necrosis factor ligand superfamily member 13B (A)"	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Intestinal immune network for IgA production (ko04672);; Rheumatoid arthritis (ko05323)	--	--	TNF(Tumour Necrosis Factor) family	"Tumor necrosis factor ligand superfamily member 13b, soluble form GN=UNQ401/PRO738 OS=Homo sapiens (Human) PE=1 SV=1"	U	"Intracellular trafficking, secretion, and vesicular transport"	tumor necrosis factor ligand superfamily member 13B [Equus caballus] 
ENSG00000102531(FNDC3A)	--	12.18384821	1253	14.34985	1490	12.74461915	1312	14.7324061	1543	15.74657907	1631	17.9178	1889	0.936125077	0.269221475	normal	0.980152154	0.108912216	normal	0.268129622	0.517064177	normal	0.070635682	0.299591668	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Fibronectin type III domain;; SusE outer membrane protein;; Interferon-alpha/beta receptor, fibronectin type III"	Fibronectin type-III domain-containing protein 3A GN=FNDC3A OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: fibronectin type-III domain-containing protein 3A isoform X1 [Ursus maritimus]
ENSG00000102539(MLNR)	--	0.780868	33	0.49891096	28	0.3289017	14	0.246869453	14	0.318182	13	0.245778029	14	0.704300439	-1.181083946	normal	0.871973272	-1.043802206	normal	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05266|0|hsa:2862|MLNR, GPR38, MTLR1; motilin receptor; K05266 motilin receptor (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srw	Motilin receptor GN=MLNR OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	Motilin receptor [Tupaia chinensis]
ENSG00000102543(CDADC1)	--	1.431338735	50	2.838029176	89	2.568397511	94	1.4565014	56	1.697725004	61	1.738282502	63	0.976594671	0.128921964	normal	0.833956539	-0.554962249	normal	0.805567192	-0.574240984	normal	0.457997625	-0.39268953	normal	[F]	Nucleotide transport and metabolism	--	--	--	[F]	Nucleotide transport and metabolism	Cytidine and deoxycytidylate deaminase zinc-binding region	Cytidine and dCMP deaminase domain-containing protein 1 GN=CDADC1 OS=Homo sapiens (Human) PE=2 SV=1	F	Nucleotide transport and metabolism	PREDICTED: cytidine and dCMP deaminase domain-containing protein 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000102547(CAB39L)	--	2.252699391	107	2.503132672	112	2.392391674	95	1.79047843	66	1.654760968	70	1.467142197	68	0.497561525	-0.714704486	normal	0.526730279	-0.687642687	normal	0.881292025	-0.481580893	normal	0.114888084	-0.643526082	normal	--	--	--	K08272|0|ptr:452718|CAB39L; calcium binding protein 39-like; K08272 calcium binding protein 39 (A)	mTOR signaling pathway (ko04150);; AMPK signaling pathway (ko04152)	[S]	Function unknown	Mo25-like	Calcium-binding protein 39-like GN=CAB39L OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: calcium-binding protein 39-like [Ursus maritimus] 
ENSG00000102554(KLF5)	--	13.01203278	769	18.84183766	1103	19.88499832	1167	22.61595949	1335	23.28730528	1384	32.72623121	1948	0.001210744	0.763780247	normal	0.905702663	0.30560984	normal	0.002323599	0.730157482	normal	0.096893256	0.599174349	normal	[R]	General function prediction only	--	K09206|0|ptr:452597|KLF5; Kruppel-like factor 5 (intestinal); K09206 krueppel-like factor 5 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 5 GN=KLF5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: Krueppel-like factor 5 [Dasypus novemcinctus]
ENSG00000102572(STK24)	--	24.3262168	1506	25.64577701	1562	24.64552631	1522	29.55899289	1818	29.52959075	1840	27.84900106	1740	0.955184578	0.240574528	normal	0.964604304	0.214693068	normal	0.971109181	0.184655789	normal	0.236846741	0.212608949	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08838|0|mcf:101926592|uncharacterized LOC101926592; K08838 serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 24 12 kDa subunit GN=STK24 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 24 isoform X1 [Galeopterus variegatus]
ENSG00000102575(ACP5)	--	0.303660792	4	0.307996	7	0.119845	1	0.386254271	10	0.785322112	7	0.439059	10	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	"K14379|0|hsa:54|ACP5, SPENCDI, TRAP; acid phosphatase 5, tartrate resistant (EC:3.1.3.2); K14379 tartrate-resistant acid phosphatase type 5 [EC:3.1.3.2] (A)"	Riboflavin metabolism (ko00740);; Lysosome (ko04142);; Osteoclast differentiation (ko04380);; Rheumatoid arthritis (ko05323)	[O]	"Posttranslational modification, protein turnover, chaperones"	Calcineurin-like phosphoesterase;; Calcineurin-like phosphoesterase superfamily domain	Tartrate-resistant acid phosphatase type 5 (Precursor) GN=ACP5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tartrate-resistant acid phosphatase type 5 [Orycteropus afer afer]
ENSG00000102580(DNAJC3)	--	10.08423197	938	10.89335983	1008	9.390136461	854	14.7006406	1373	12.57156074	1166	15.77391829	1465	0.260606847	0.51813429	normal	0.962795334	0.18838263	normal	0.000949207	0.769248839	normal	0.001166051	0.494702954	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	"K09523|0|hsa:5611|DNAJC3, ERdj6, HP58, P58, P58IPK, PRKRI; DnaJ (Hsp40) homolog, subfamily C, member 3; K09523 DnaJ homolog subfamily C member 3 (A)"	Protein processing in endoplasmic reticulum (ko04141);; Influenza A (ko05164)	[V]	Defense mechanisms	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; DnaJ domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	DnaJ homolog subfamily C member 3 (Precursor) GN=DNAJC3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 3 [Ailuropoda melanoleuca] 
ENSG00000102595(UGGT2)	--	12.23502352	786	15.1393782	852	11.45862157	722	7.874224667	535	8.91208127	540	8.867631337	607	0.107153961	-0.58442853	normal	0.01867161	-0.677795503	normal	0.925917692	-0.258003597	normal	0.002710415	-0.509667159	normal	--	--	"Molecular Function: UDP-glucose:glycoprotein glucosyltransferase activity (GO:0003980);; Biological Process: protein glycosylation (GO:0006486);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K11718|0|hsa:55757|UGGT2, HUGT2, UGCGL2, UGT2; UDP-glucose glycoprotein glucosyltransferase 2; K11718 UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-] (A)"	Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	UDP-glucose:Glycoprotein Glucosyltransferase;; Glycosyl transferase family 8	UDP-glucose:glycoprotein glucosyltransferase 2 (Precursor) GN=UGGT2 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucose:glycoprotein glucosyltransferase 2 [Ceratotherium simum simum]
ENSG00000102606(ARHGEF7)	--	11.32982013	896	9.5334212	789	12.89497846	885	12.10310214	900	10.02519033	879	12.29238307	915	0.978068531	-0.024364309	normal	0.968715529	0.134167586	normal	0.977787502	0.039736066	normal	0.87390307	0.04694717	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K13710|0|hsa:8874|ARHGEF7, BETA-PIX, COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, P85SPR, PAK3, PIXB; Rho guanine nucleotide exchange factor (GEF) 7; K13710 Rho guanine nucleotide exchange factor 7 (A)"	Regulation of actin cytoskeleton (ko04810)	[F]	Nucleotide transport and metabolism	RhoGEF domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; PH domain;; Calponin homology (CH) domain	Rho guanine nucleotide exchange factor 7 GN=Nbla10314 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 7 isoform 2 [Trichechus manatus latirostris]
ENSG00000102678(FGF9)	--	0.0162372	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|3.25599e-139|umr:103664292|FGF9; fibroblast growth factor 9; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 9 (Precursor) GN=FGF9 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 9 [Loxodonta africana] 
ENSG00000102683(SGCG)	--	0	0	0	0	0	0	0.0726607	2	0.0709906	1	0.0727104	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: sarcoglycan complex (GO:0016012);; Cellular Component: integral component of membrane (GO:0016021);; 	"K12564|0|hsa:6445|SGCG, A4, DAGA4, DMDA, DMDA1, LGMD2C, MAM, SCARMD2, SCG3, TYPE; sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein); K12564 gamma-sarcoglycan (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	[Z]	Cytoskeleton	Sarcoglycan complex subunit protein	Gamma-sarcoglycan GN=SGCG OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	gamma-sarcoglycan [Canis lupus familiaris] 
ENSG00000102699(PARP4)	--	22.4089	2473	25.7071	2820	24.1287	2624	25.3653	2798	24.3904	2680	26.5565	2933	0.983393036	0.147215438	normal	0.987225529	-0.094836542	normal	0.983520746	0.152234884	normal	0.788536404	0.066210253	normal	[R]	General function prediction only	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K10798|0|hsa:143|PARP4, ADPRTL1, ARTD4, PARP-4, PARPL, PH5P, VAULT3, VPARP, VWA5C, p193; poly (ADP-ribose) polymerase family, member 4 (EC:2.4.2.30); K10798 poly [ADP-ribose] polymerase [EC:2.4.2.30] (A)"	Base excision repair (ko03410)	--	--	Poly(ADP-ribose) polymerase catalytic domain;; Vault protein inter-alpha-trypsin domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; Vault protein inter-alpha-trypsin domain;; BRCA1 C Terminus (BRCT) domain;; von Willebrand factor type A domain	Poly [ADP-ribose] polymerase 4 GN=PARP4 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: poly [ADP-ribose] polymerase 4 [Galeopterus variegatus]
ENSG00000102710(SUPT20H)	--	13.6043652	716	14.88016416	799	14.66369019	777	15.05611677	815	11.65788731	642	14.91884067	819	0.964353381	0.155694914	normal	0.85372525	-0.336336993	normal	0.975116015	0.067529381	normal	0.921550172	-0.031366876	normal	--	--	Cellular Component: SAGA complex (GO:0000124);; Molecular Function: transcription cofactor activity (GO:0003712);; 	--	--	--	--	Spt20 family	Transcription factor SPT20 homolog GN=SUPT20H OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transcription factor SPT20 homolog isoform X3 [Canis lupus familiaris] 
ENSG00000102738(MRPS31)	--	8.012835	224	8.692192	240	8.93249	246	8.936161	250	11.301794	314	8.358011	234	0.960090506	0.126773763	normal	0.839674517	0.364291471	normal	0.964487838	-0.079937307	normal	0.679381374	0.147427754	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: mitochondrial small ribosomal subunit (GO:0005763);; 	"K17410|0|hsa:10240|MRPS31, IMOGN38, MRP-S31, S31mt; mitochondrial ribosomal protein S31; K17410 small subunit ribosomal protein S31 (A)"	--	--	--	Mitochondrial 28S ribosomal protein S31	"28S ribosomal protein S31, mitochondrial (Precursor) GN=MRPS31 OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S31, mitochondrial isoformX1 [Equus caballus]"
ENSG00000102743(SLC25A15)	--	9.127895065	566	8.945131093	556	9.819981487	561	7.597335	505	7.599478942	427	6.764451092	420	0.950141503	-0.194790725	normal	0.735664582	-0.401026716	normal	0.665745004	-0.424575345	normal	0.103846389	-0.33773649	normal	--	--	--	"K15101|0|hsa:10166|SLC25A15, D13S327, HHH, ORC1, ORNT1; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; K15101 solute carrier family 25 (mitochondrial ornithine transporter) member 2/15 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial ornithine transporter 1 GN=SLC25A15 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 [Sus scrofa]
ENSG00000102753(KPNA3)	--	24.926349	1739	25.210211	1778	26.211307	1802	24.804057	1749	25.00075	1744	20.018138	1425	0.985431199	-0.02254005	normal	0.984622735	-0.049239554	normal	0.86266772	-0.346600649	normal	0.516566157	-0.13478492	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein import into nucleus (GO:0006606);; Molecular Function: protein transporter activity (GO:0008565);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Armadillo/beta-catenin-like repeat;; Importin beta binding domain;; HEAT repeats;; HEAT-like repeat;; HEAT repeat;; Adaptin N terminal region;; Armadillo-like;; V-ATPase subunit H;; Proteasome non-ATPase 26S subunit	Importin subunit alpha-4 GN=KPNA3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin subunit alpha-4 [Orycteropus afer afer]
ENSG00000102755(FLT1)	--	0	0	0	0	0	0	0	0	0	0	0.056374341	2	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05096|0|pps:100977352|FLT1; fms-related tyrosine kinase 1; K05096 FMS-like tyrosine kinase 1 [EC:2.7.10.1] (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Transcriptional misregulation in cancer (ko05202);; Rheumatoid arthritis (ko05323)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Protein kinase domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin C1-set domain;; Alphaherpesvirus glycoprotein E;; CD80-like C2-set immunoglobulin domain	Vascular endothelial growth factor receptor 1 (Precursor) GN=FLT1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: vascular endothelial growth factor receptor 1 [Ceratotherium simum simum]
ENSG00000102760(RGCC)	--	0.846491	12	0.896683	13	0.87267	12	0.406118	6	0.677908	9	1.03325	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of cell cycle (GO:0051726);; 	--	--	--	--	Response gene to complement 32 protein family	Regulator of cell cycle RGCC GN=RGCC OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: regulator of cell cycle RGCC [Orycteropus afer afer]
ENSG00000102763(VWA8)	--	5.396819	615	5.807303338	667	5.62421	641	5.352257528	635	6.392914533	682	5.063722	668	0.974006952	0.015300301	normal	0.974351084	0.010634575	normal	0.973607571	0.051114168	normal	0.947264022	0.024753972	normal	--	--	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	--	--	[R]	General function prediction only	AAA domain (dynein-related subfamily);; von Willebrand factor type A domain;; AAA domain;; von Willebrand factor type A domain;; ATPase family associated with various cellular activities (AAA);; ATPase family associated with various cellular activities (AAA)	von Willebrand factor A domain-containing protein 8 (Precursor) GN=VWA8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	"PREDICTED: von Willebrand factor A domain-containing protein 8, partial [Tupaia chinensis]"
ENSG00000102780(DGKH)	--	2.817263791	454	3.350268888	636	2.609554297	493	3.260288245	664	3.248269178	633	3.762208569	699	0.32010332	0.516206476	normal	0.973350751	-0.028180657	normal	0.395503613	0.494134173	normal	0.11673534	0.313141615	normal	--	--	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|mcf:102134655|DGKH; diacylglycerol kinase, eta; K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; PH domain;; SAM domain (Sterile alpha motif);; Phorbol esters/diacylglycerol binding domain (C1 domain);; SAM domain (Sterile alpha motif)	Diacylglycerol kinase eta GN=DGKH OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: diacylglycerol kinase eta isoform 1 [Ceratotherium simum simum]
ENSG00000102781(KATNAL1)	--	5.570128	612	5.981309	669	6.107697764	670	5.977605	592	5.049163	556	4.987676269	510	0.970922589	-0.078566176	normal	0.904282455	-0.287633503	normal	0.720722422	-0.40091475	normal	0.222801065	-0.256340476	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	K07767|0|hsa:84056|KATNAL1; katanin p60 subunit A-like 1 (EC:3.6.4.3); K07767 katanin p60 ATPase-containing subunit A1 [EC:3.6.4.3] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; Vps4 C terminal oligomerisation domain;; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (Cdc48 subfamily)	Katanin p60 ATPase-containing subunit A-like 1 {ECO:0000255|HAMAP-Rule:MF_03024} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: katanin p60 ATPase-containing subunit A-like 1 isoform X1 [Tupaia chinensis] 
ENSG00000102786(INTS6)	--	7.475788207	641	6.3487208	565	7.019050959	594	6.037512235	518	8.505657953	729	6.43364677	563	0.847624311	-0.337303123	normal	0.839367789	0.345425509	normal	0.970051024	-0.0853961	normal	0.978728302	-0.012808693	normal	--	--	--	K13143|0|mcf:102137315|INTS6; integrator complex subunit 6; K13143 integrator complex subunit 6 (A)	--	[R]	General function prediction only	INTS6/SAGE1/DDX26B/CT45 C-terminus;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Integrator complex subunit 6 GN=INTS6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: integrator complex subunit 6 [Ailuropoda melanoleuca] 
ENSG00000102796(DHRS12)	--	4.137795808	85	4.149038343	80	3.726674572	81	3.012407752	62	4.652943418	78	3.386240494	69	0.900075713	-0.475909063	normal	0.971468143	-0.056863768	normal	0.963080647	-0.234860837	normal	0.652922286	-0.255963621	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	K11168|0|ptr:743256|DHRS12; dehydrogenase/reductase (SDR family) member 12; K11168 dehydrogenase/reductase SDR family member 12 [EC:1.1.-.-] (A)	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; NAD dependent epimerase/dehydratase family;; KR domain	Dehydrogenase/reductase SDR family member 12 GN=DHRS12 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 12 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000102802(MEDAG)	--	0.0251658	1	0	0	0.027864383	0	0.278624067	1	0.170757719	6	0.0248927	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Mesenteric estrogen-dependent adipogenesis protein GN=MEDAG OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: mesenteric estrogen-dependent adipogenesis protein [Tupaia chinensis] 
ENSG00000102804(TSC22D1)	--	37.77458327	2424	28.93023675	2093	29.7276569	1962	21.84050944	1677	28.81187867	2292	28.69311811	2198	0.128312689	-0.561908374	normal	0.984104875	0.10953253	normal	0.979508428	0.155461636	normal	0.777925229	-0.091740409	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	TSC-22/dip/bun family	TSC22 domain family protein 1 GN=TSC22D1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: TSC22 domain family protein 1 isoform X1 [Equus caballus]
ENSG00000102805(CLN5)	--	10.206601	408	10.1887708	411	10.4388599	410	9.64868648	398	11.07626757	453	9.0636725	384	0.967755134	-0.066379877	normal	0.962742338	0.118530565	normal	0.964783996	-0.102418609	normal	0.977448148	-0.014186751	normal	--	--	Cellular Component: lysosome (GO:0005764);; 	"K12390|0|hsa:1203|CLN5, NCL; ceroid-lipofuscinosis, neuronal 5; K12390 ceroid-lipofuscinosis neuronal protein 5 (A)"	Lysosome (ko04142)	--	--	Ceroid-lipofuscinosis neuronal protein 5	Ceroid-lipofuscinosis neuronal protein 5 (Precursor) GN=CLN5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ceroid-lipofuscinosis neuronal protein 5 [Myotis lucifugus]
ENSG00000102837(OLFM4)	--	0	0	0.269099	13	0.228262	10	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Olfactomedin-like domain	Olfactomedin-4 (Precursor) GN=OLFM4 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	Olfactomedin-4 [Tupaia chinensis]
ENSG00000102854(MSLN)	--	2.9937591	110	2.060196395	81	2.423385743	89	0.610076934	24	0.818776166	30	1.384265648	24	6.36E-09	-2.156576737	down	0.003403601	-1.409410578	down	1.10E-05	-1.834897803	down	3.70E-06	-1.865009936	down	--	--	--	--	--	--	--	Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)	"Mesothelin, cleaved form (Precursor) GN=MSLN OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	PREDICTED: mesothelin-like [Galeopterus variegatus]
ENSG00000102858(MGRN1)	--	17.5197052	1356	17.69820606	1398	16.97322336	1325	27.20654695	2032	22.87575257	1750	21.34227037	1704	0.151472442	0.552196737	normal	0.917384929	0.302271224	normal	0.846469998	0.35428407	normal	0.007656702	0.405699333	normal	--	--	--	"K10604|0|ptr:453884|MGRN1; mahogunin ring finger 1, E3 ubiquitin protein ligase; K10604 E3 ubiquitin-protein ligase MGRN1 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase MGRN1 GN=MGRN1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MGRN1 isoform X1 [Galeopterus variegatus]
ENSG00000102870(ZNF629)	--	9.737913	1346	10.0835141	1389	9.026225	1259	9.72227	1341	11.248226	1546	9.182374	1276	0.982448836	-0.036160083	normal	0.977056478	0.132929934	normal	0.982243349	0.011045425	normal	0.890794781	0.038394093	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; TFIIH C1-like domain;; Zinc ribbon domain"	Zinc finger protein 629 GN=ZNF629 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 629 [Ailuropoda melanoleuca]
ENSG00000102871(TRADD)	--	16.55514	450	12.19608	345	16.30808	473	15.57458	435	14.80634	399	14.1214	388	0.967652056	-0.079465878	normal	0.948623393	0.18760064	normal	0.898423002	-0.293038739	normal	0.825685166	-0.074491047	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Biological Process: positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123);; 	"K03171|2.44097e-180|hsa:8717|TRADD, Hs.89862; TNFRSF1A-associated via death domain; K03171 tumor necrosis factor receptor type 1-associated DEATH domain protein (A)"	NF-kappa B signaling pathway (ko04064);; Sphingolipid signaling pathway (ko04071);; Apoptosis (ko04210);; RIG-I-like receptor signaling pathway (ko04622);; TNF signaling pathway (ko04668);; Adipocytokine signaling pathway (ko04920);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	--	--	"TRADD, N-terminal domain;; Death domain"	Tumor necrosis factor receptor type 1-associated DEATH domain protein GN=TRADD OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor type 1-associated DEATH domain protein [Camelus bactrianus] 
ENSG00000102878(HSF4)	--	1.986101646	47	4.043808555	60	2.39986992	63	3.477903022	49	2.24085665	48	2.15409983	59	0.979595319	0.028380121	normal	0.959633346	-0.333923978	normal	0.975018885	-0.100436501	normal	0.853525777	-0.144391314	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09417|0|hsa:3299|HSF4, CTM, CTRCT5; heat shock transcription factor 4; K09417 heat shock transcription factor 4 (A)"	--	[K]	Transcription	HSF-type DNA-binding	Heat shock factor protein 4 GN=HSF4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: heat shock factor protein 4 isoform X1 [Galeopterus variegatus]
ENSG00000102879(CORO1A)	--	2.21928474	77	0.495879777	18	1.853234312	61	1.823726599	51	1.258110909	43	0.348388899	10	0.828207802	-0.610123269	normal	0.480061057	1.169588533	normal	3.02E-06	-2.448611813	down	0.652179	-0.608882531	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K13882|0|hsa:11151|CORO1A, CLABP, CLIPINA, HCORO1, IMD8, TACO, p57; coronin, actin binding protein, 1A; K13882 coronin-1A (A)"	Phagosome (ko04145);; Tuberculosis (ko05152)	[Z]	Cytoskeleton	"Domain of unknown function (DUF1900);; Domain of unknown function (DUF1899);; WD domain, G-beta repeat"	Coronin-1A GN=CORO1A OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: coronin-1A isoform 1 [Canis lupus familiaris]
ENSG00000102882(MAPK3)	--	36.482451	1182	25.77747435	798	34.5124748	1012	24.72335157	725	25.231857	767	26.19502266	817	0.002789309	-0.734776681	normal	0.973579831	-0.078437092	normal	0.882023163	-0.316565196	normal	0.129983792	-0.394543676	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04371|0|pon:100431824|MAPK3; mitogen-activated protein kinase 3; K04371 mitogen-activated protein kinase 1/3 [EC:2.7.11.24] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Dorso-ventral axis formation (ko04320);; TGF-beta signaling pathway (ko04350);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Aldosterone-regulated sodium reabsorption (ko04960);; Alzheimer's disease (ko05010);; Prion diseases (ko05020);; Alcoholism (ko05034);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Mitogen-activated protein kinase 3 GN=MAPK3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 3 [Physeter catodon]
ENSG00000102886(GDPD3)	--	0.261017509	6	0.424956637	10	0.086988147	1	0.560784925	13	0.127018187	2	0.128977064	3	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; 	--	--	[C]	Energy production and conversion	Glycerophosphoryl diester phosphodiesterase family	Glycerophosphodiester phosphodiesterase domain-containing protein 3 GN=GDPD3 OS=Homo sapiens (Human) PE=2 SV=3	C	Energy production and conversion	PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 3 [Ovis aries]
ENSG00000102890(ELMO3)	--	0.493789568	21	0.60628778	30	0.379035651	16	0.443157813	19	0.38891125	16	0.465266304	20	0.988441673	-0.162701278	normal	0.91657371	-0.867534341	normal	0.987663316	0.289151398	normal	0.754536824	-0.306687983	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3361);; ELMO/CED-12 family	Engulfment and cell motility protein 3 GN=ELMO3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: engulfment and cell motility protein 3 isoform X1 [Vicugna pacos]
ENSG00000102893(PHKB)	--	27.4640532	1798	28.76145592	1831	31.39022848	1790	33.98872896	2093	34.19995237	2096	33.47900375	1873	0.973332643	0.18819787	normal	0.975901568	0.173446397	normal	0.98515477	0.057052746	normal	0.490663328	0.140249659	normal	--	--	--	"K07190|0|mcf:102138981|PHKB; phosphorylase kinase, beta; K07190 phosphorylase kinase alpha/beta subunit (A)"	Calcium signaling pathway (ko04020);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 15	Phosphorylase b kinase regulatory subunit beta GN=PHKB OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	phosphorylase kinase beta-subunit [Oryctolagus cuniculus]
ENSG00000102897(LYRM1)	--	20.10243575	418	14.61861158	308	19.9201494	376	28.679022	558	26.16825915	470	24.21999905	498	0.767398069	0.384702455	normal	0.184206609	0.585958826	normal	0.750455479	0.39573428	normal	0.027765962	0.448155135	normal	--	--	--	--	--	--	--	Complex 1 protein (LYR family);; Complex1_LYR-like	LYR motif-containing protein 1 GN=LYRM1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LYR motif-containing protein 1 [Physeter catodon]
ENSG00000102898(NUTF2)	--	97.343567	2086	95.38285	2176	91.48644482	2140	116.088384	2686	109.658668	2527	103.795693	2340	0.901009084	0.333670824	normal	0.97523433	0.194195219	normal	0.983868126	0.120524817	normal	0.220840964	0.216924027	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Nuclear transport factor 2 (NTF2) domain	Nuclear transport factor 2 GN=NUTF2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: nuclear transport factor 2 isoform X1 [Loxodonta africana]
ENSG00000102900(NUP93)	--	33.56885362	1784	29.54353728	1534	32.7198026	1717	37.36208118	1900	35.40499065	1777	26.44552436	1427	0.985089044	0.060001465	normal	0.969949236	0.190543987	normal	0.936335195	-0.274930126	normal	0.999953667	-0.002271423	normal	--	--	Cellular Component: nuclear pore (GO:0005643);; Biological Process: transport (GO:0006810);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Nup93/Nic96	Nuclear pore complex protein Nup93 GN=NUP93 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nuclear pore complex protein Nup93 isoform X1 [Oryctolagus cuniculus] 
ENSG00000102901(CENPT)	--	9.198602295	405	9.611175717	435	9.648365593	439	10.23611503	451	10.66881296	471	8.864017406	401	0.962683954	0.123927618	normal	0.965993363	0.092974426	normal	0.960544601	-0.13841107	normal	0.947851397	0.02738154	normal	[B]	Chromatin structure and dynamics	Cellular Component: FANCM-MHF complex (GO:0071821);; 	"K11512|0|hsa:80152|CENPT, C16orf56, CENP-T; centromere protein T; K11512 centromere protein T (A)"	--	--	--	Centromere kinetochore component CENP-T;; Kinetochore component CENP-S;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Centromere protein T GN=CENPT OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centromere protein T [Vicugna pacos]
ENSG00000102904(TSNAXIP1)	--	0.46242155	22	0.361389836	18	0.53086696	25	0.359053915	13	0.432081464	16	0.692563822	24	0.971576593	-0.723417713	normal	--	--	--	0.986746054	-0.063278113	normal	0.747230811	-0.313349215	normal	--	--	--	--	--	--	--	--	Translin-associated factor X-interacting protein 1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: translin-associated factor X-interacting protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000102908(NFAT5)	--	16.61767996	3028	24.23620398	4271	17.84431889	3215	13.23971	2295	14.14870381	2584	21.4340152	3917	0.685518271	-0.430451509	normal	0.001844902	-0.746050979	normal	0.959915183	0.276520928	normal	0.575238441	-0.277272142	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K17335|0|hsa:10725|NFAT5, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP; nuclear factor of activated T-cells 5, tonicity-responsive; K17335 nuclear factor of activated T-cells 5 (A)"	--	--	--	Rel homology domain (RHD)	Nuclear factor of activated T-cells 5 GN=NFAT5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear factor of activated T-cells 5 isoform 1 [Ceratotherium simum simum]
ENSG00000102910(LONP2)	--	15.48459142	1780	18.3320967	1957	17.80476451	2060	18.2713938	2150	17.03740575	1933	16.71171259	1934	0.958924204	0.241437317	normal	0.985865551	-0.039198198	normal	0.984082538	-0.099272755	normal	0.906116239	0.032355285	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP-dependent peptidase activity (GO:0004176);; Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: ATP binding (GO:0005524);; Biological Process: proteolysis (GO:0006508);; Molecular Function: ATPase activity (GO:0016887);; 	"K01338|0|pps:100978594|LONP2; lon peptidase 2, peroxisomal; K01338 ATP-dependent Lon protease [EC:3.4.21.53] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Lon protease (S16) C-terminal proteolytic domain;; ATP-dependent protease La (LON) domain;; ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily);; AAA ATPase domain	"Lon protease homolog 2, peroxisomal {ECO:0000255|HAMAP-Rule:MF_03121} OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: lon protease homolog 2, peroxisomal [Galeopterus variegatus]"
ENSG00000102921(N4BP1)	--	7.413752752	941	6.612450502	803	7.411769041	932	7.007307026	884	6.420944514	809	6.571038809	833	0.972165378	-0.120777104	normal	0.976470284	-0.010666829	normal	0.96382256	-0.170012933	normal	0.667417991	-0.104469537	normal	--	--	--	--	--	[S]	Function unknown	Zc3h12a-like Ribonuclease NYN domain	NEDD4-binding protein 1 GN=N4BP1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: NEDD4-binding protein 1 [Lipotes vexillifer]
ENSG00000102924(CBLN1)	--	0	0	0.02573466	1	0	0	0	0	0.077196	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain	[des-Ser1]-cerebellin (Precursor) GN=CBLN1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	Cerebellin-1 [Tupaia chinensis]
ENSG00000102931(ARL2BP)	--	12.807899	353	13.96766	406	13.767203	423	17.122856	514	13.11	408	15.014227	468	0.388505935	0.509420926	normal	0.968968274	-0.014284059	normal	0.961251002	0.137093281	normal	0.400659459	0.212447075	normal	--	--	--	K16742|1.83582e-70|ptr:736837|ARL2BP; ADP-ribosylation factor-like 2 binding protein; K16742 ADP-ribosylation factor-like protein 2-binding protein (A)	--	--	--	The ARF-like 2 binding protein BART	ADP-ribosylation factor-like protein 2-binding protein GN=ARL2BP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ADP-ribosylation factor-like protein 2-binding protein isoform X2 [Felis catus]
ENSG00000102934(PLLP)	--	9.045742541	885	7.266858	863	7.49561	863	10.8996907	1213	11.24517236	1085	10.85270096	1170	0.644751129	0.423367876	normal	0.894987995	0.308353209	normal	0.620762728	0.430134873	normal	0.017180691	0.388140041	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	Plasmolipin GN=PLLP OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: plasmolipin [Vicugna pacos]
ENSG00000102935(ZNF423)	--	0.037258752	4	0.051809173	5	0.021803064	1	0.047103882	5	0.485932222	8	0.046203367	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Drought induced 19 protein (Di19), zinc-binding;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; C2H2 type zinc-finger (2 copies)"	Zinc finger protein 423 GN=ZNF423 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 423 isoform X2 [Bos taurus]
ENSG00000102967(DHODH)	--	7.462435888	364	7.871250058	414	7.289151923	395	5.286775496	254	5.432149371	289	4.765569708	256	0.339150435	-0.547160908	normal	0.349622559	-0.537623751	normal	0.112000286	-0.630975582	normal	0.007755242	-0.575033073	normal	[F]	Nucleotide transport and metabolism	"Cellular Component: cytoplasm (GO:0005737);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00254|0|hsa:1723|DHODH, DHOdehase, POADS, URA1; dihydroorotate dehydrogenase (quinone) (EC:1.3.5.2); K00254 dihydroorotate dehydrogenase [EC:1.3.5.2] (A)"	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Dihydroorotate dehydrogenase	"Dihydroorotate dehydrogenase (quinone), mitochondrial (Precursor) GN=DHODH OS=Homo sapiens (Human) PE=1 SV=3"	F	Nucleotide transport and metabolism	"PREDICTED: dihydroorotate dehydrogenase (quinone), mitochondrial [Orcinus orca]"
ENSG00000102974(CTCF)	--	16.56480533	1471	17.28739033	1543	16.44192506	1440	17.51527715	1546	19.86808511	1760	19.95494657	1787	0.983586041	0.04086917	normal	0.974027928	0.168256319	normal	0.915923109	0.302893308	normal	0.370257157	0.172599752	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Transcriptional repressor CTCF GN=CTCF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcriptional repressor CTCF isoform X3 [Oryctolagus cuniculus]
ENSG00000102977(ACD)	--	14.47910629	409	14.64908669	419	16.06017809	474	16.76450832	448	13.09729269	364	12.81333872	362	0.965506349	0.100205891	normal	0.937434633	-0.223571755	normal	0.75350762	-0.3957395	normal	0.536115465	-0.170962826	normal	--	--	--	"K11114|0|hsa:65057|ACD, PIP1, PTOP, TINT1, TPP1; adrenocortical dysplasia homolog (mouse); K11114 adrenocortical dysplasia protein (A)"	--	--	--	"Shelterin complex subunit, TPP1/ACD"	Adrenocortical dysplasia protein homolog GN=ACD OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: adrenocortical dysplasia protein homolog [Ceratotherium simum simum]
ENSG00000102978(POLR2C)	--	32.8434	1181	30.1768	1089	31.6563	1142	38.0555	1376	42.1329	1511	38.6294	1395	0.965640019	0.189410795	normal	0.567252145	0.450539846	normal	0.926221057	0.280074929	normal	0.065663071	0.306595005	normal	[K]	Transcription	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K03011|0|ptr:454119|POLR2C; polymerase (RNA) II (DNA directed) polypeptide C, 33kDa; K03011 DNA-directed RNA polymerase II subunit RPB3 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpb3/RpoA insert domain;; RNA polymerase Rpb3/Rpb11 dimerisation domain	DNA-directed RNA polymerase II subunit RPB3 GN=POLR2C OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	DNA-directed RNA polymerase II subunit RPB3 [Tupaia chinensis]
ENSG00000102981(PARD6A)	--	4.724873857	91	4.665785149	93	4.79173774	96	2.45541107	49	2.059897852	40	5.787405331	115	0.229670457	-0.902804714	normal	0.011671272	-1.207828325	normal	0.952019199	0.248652842	normal	0.507768036	-0.475314232	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06093|0|pps:100982056|PARD6A; par-6 family cell polarity regulator alpha; K06093 partitioning defective protein 6 (A)	Rap1 signaling pathway (ko04015);; Endocytosis (ko04144);; Hippo signaling pathway (ko04390);; Tight junction (ko04530)	[T]	Signal transduction mechanisms	PB1 domain;; PDZ domain (Also known as DHR or GLGF)	Partitioning defective 6 homolog alpha GN=PARD6A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: partitioning defective 6 homolog alpha isoform X1 [Equus caballus] 
ENSG00000102984(ZNF821)	--	2.795664007	111	1.4963664	62	2.468955267	96	2.6121578	105	2.4927004	99	2.0589569	85	0.967319474	-0.109444694	normal	0.695749879	0.641253952	normal	0.964443061	-0.180833644	normal	0.903207025	0.081969255	normal	--	--	--	--	--	[R]	General function prediction only	Zinc-finger of C2H2 type	Zinc finger protein 821 GN=ZNF821 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 821 isoformX1 [Canis lupus familiaris] 
ENSG00000102996(MMP15)	--	19.2207	1444	14.235301	1035	16.1993	1258	13.6415	1023	16.211	1215	16.18700035	1226	0.224957608	-0.527426423	normal	0.95762009	0.209616063	normal	0.981361194	-0.045409087	normal	0.66433168	-0.129954627	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K07995|0|hsa:4324|MMP15, MT2-MMP, MTMMP2, SMCP-2; matrix metallopeptidase 15 (membrane-inserted) (EC:3.4.24.-); K07995 matrix metalloproteinase-15 (membrane-inserted) [EC:3.4.24.-] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Domain of unknown function (DUF3377);; Putative peptidoglycan binding domain	Matrix metalloproteinase-15 (Precursor) GN=MMP15 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	matrix metalloproteinase-15 precursor [Bos taurus] 
ENSG00000103005(USB1)	--	70.98621518	2450	61.20159354	2171	77.72782664	2737	64.75672138	2306	64.12103006	2235	60.603454	2149	0.984701862	-0.118145112	normal	0.987312775	0.020474491	normal	0.869994893	-0.356998216	normal	0.416469987	-0.158370382	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000103018(CYB5B)	--	229.7073911	6828	241.4720026	7707	223.81372	6998	129.63355	3940	127.0051057	4128	187.65077	5923	0.000125785	-0.823852325	normal	6.71E-06	-0.921901581	normal	0.980515951	-0.248847495	normal	0.001654888	-0.642114755	normal	[CI]	Energy production and conversion;; Lipid transport and metabolism	--	--	--	[C]	Energy production and conversion	Cytochrome b5-like Heme/Steroid binding domain	Cytochrome b5 type B (Precursor) GN=CYB5B OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: cytochrome b5 type B [Felis catus]
ENSG00000103021(CCDC113)	--	2.097324823	183	2.377264896	159	2.315552537	180	4.252306477	313	4.942217052	295	3.167977228	247	0.034385649	0.738692704	normal	0.005097961	0.864137157	normal	0.742081901	0.445018296	normal	0.004699402	0.690130003	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4201)	Coiled-coil domain-containing protein 113 GN=CCDC113 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 113 isoform X1 [Leptonychotes weddellii]
ENSG00000103023(PRSS54)	--	0.404581	12	0.535869555	16	0.596145	17	1.106550001	33	1.411480004	41	1.33371	40	0.574725127	1.322872643	normal	0.403777347	1.25939214	normal	0.572907199	1.157253495	normal	0.021898915	1.320775997	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin	Inactive serine protease 54 (Precursor) GN=PRSS54 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: inactive serine protease 54 [Tupaia chinensis]
ENSG00000103024(NME3)	--	35.239873	429	26.55469	332	28.719047	368	32.001055	398	37.34577	463	29.57428	362	0.960259671	-0.138526215	normal	0.602098389	0.45663374	normal	0.968642236	-0.031875436	normal	0.774759408	0.0940205	normal	[F]	Nucleotide transport and metabolism	--	K00940|9.51051e-121|pps:100985482|NME3; NME/NM23 nucleoside diphosphate kinase 3; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Nucleoside diphosphate kinase	Nucleoside diphosphate kinase 3 GN=NME3 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: nucleoside diphosphate kinase 3 [Camelus bactrianus]
ENSG00000103034(NDRG4)	--	10.15366976	591	11.62915045	602	11.71271561	684	15.47982256	793	16.46944946	932	14.74632921	888	0.737969145	0.392447004	normal	0.072778309	0.607903508	normal	0.796974231	0.36755676	normal	0.006860043	0.456726014	normal	--	--	--	--	--	[S]	Function unknown	Ndr family;; Alpha/beta hydrolase family	Protein NDRG4 GN=NDRG4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein NDRG4-A isoform X3 [Mustela putorius furo]
ENSG00000103035(PSMD7)	--	74.76760002	2181	67.512144	1938	66.579999	1952	77.731949	2371	80.123342	2298	69.783669	2008	0.985956851	0.089613074	normal	0.966450923	0.224222832	normal	0.9865199	0.032489956	normal	0.585518535	0.115537273	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03038|0|ptr:454240|PSMD7; proteasome (prosome, macropain) 26S subunit, non-ATPase, 7; K03038 26S proteasome regulatory subunit N8 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Maintenance of mitochondrial structure and function;; JAB1/Mov34/MPN/PAD-1 ubiquitin protease	26S proteasome non-ATPase regulatory subunit 7 GN=PSMD7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 7 [Orycteropus afer afer]
ENSG00000103037(SETD6)	--	5.44736	214	5.11343	200	4.52459	183	5.002294	184	4.65362	179	4.123228	167	0.935923601	-0.246823906	normal	0.951969406	-0.180027173	normal	0.959976028	-0.139083359	normal	0.618438572	-0.193408384	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05302|0|hsa:79918|SETD6; SET domain containing 6; K05302 SET domain-containing protein 6 (A)	--	[S]	Function unknown	SET domain;; Rubisco LSMT substrate-binding	N-lysine methyltransferase SETD6 GN=SETD6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: N-lysine methyltransferase SETD6 isoform 1 [Odobenus rosmarus divergens]
ENSG00000103042(SLC38A7)	--	10.7566028	591	14.46670092	775	13.82344246	672	12.80168928	769	10.88424801	719	18.89263791	1138	0.831136953	0.348197733	normal	0.967835229	-0.129368927	normal	0.002033803	0.750363678	normal	0.420566859	0.345596746	normal	--	--	Biological Process: amino acid transmembrane transport (GO:0003333);; 	"K14994|0|hsa:55238|SLC38A7, SNAT7; solute carrier family 38, member 7; K14994 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 7/8 (A)"	--	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein;; Tryptophan/tyrosine permease family	Putative sodium-coupled neutral amino acid transporter 7 GN=SLC38A7 OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: putative sodium-coupled neutral amino acid transporter 7 [Equus przewalskii] 
ENSG00000103043(VAC14)	--	15.648359	1060	16.5427931	1107	17.362435	1170	14.90965092	1044	16.27073325	1148	20.93079105	1389	0.979110884	-0.052697847	normal	0.980149222	0.030999277	normal	0.949684775	0.238962825	normal	0.764305421	0.08161088	normal	--	--	--	"K15305|0|hsa:55697|VAC14, ArPIKfyve, TAX1BP2, TRX; Vac14 homolog (S. cerevisiae); K15305 vacuole morphology and inheritance protein 14 (A)"	HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[S]	Function unknown	Vacuolar protein 14 C-terminal Fig4p binding;; Vacuolar 14 Fab1-binding region;; HEAT repeat;; HEAT-like repeat	Protein VAC14 homolog GN=VAC14 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein VAC14 homolog [Galeopterus variegatus]
ENSG00000103044(HAS3)	--	22.47335306	1519	20.98649744	1545	20.83863419	1625	26.32929812	2084	17.784974	1356	12.282644	944	0.668573299	0.42503279	normal	0.962850303	-0.209457186	normal	0.000463684	-0.790894565	normal	0.86004431	-0.120553572	normal	[M]	Cell wall/membrane/envelope biogenesis	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	K00752|0|ptr:454195|HAS3; hyaluronan synthase 3; K00752 hyaluronan synthase [EC:2.4.1.212] (A)	--	[M]	Cell wall/membrane/envelope biogenesis	Glycosyltransferase like family 2;; Chitin synthase;; Glycosyl transferase family group 2;; Glycosyl transferase family 2;; Glycosyl transferase family 21	Hyaluronan synthase 3 GN=HAS3 OS=Homo sapiens (Human) PE=1 SV=3	M	Cell wall/membrane/envelope biogenesis	hyaluronan synthase 3 [Bos taurus] 
ENSG00000103047(TANGO6)	--	7.712922695	794	7.041643729	741	7.886503	829	6.181821904	634	6.941218424	703	5.745565677	590	0.819855772	-0.354718371	normal	0.971038812	-0.097171773	normal	0.362119799	-0.497866668	normal	0.09127178	-0.316043038	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF2435);; Domain of unknown function (DUF2411);; HEAT repeats	Transport and Golgi organization protein 6 homolog GN=TANGO6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transport and Golgi organization protein 6 homolog [Eptesicus fuscus]
ENSG00000103051(COG4)	--	21.90528429	1122	21.49878088	1017	23.75685252	1164	24.09921422	1187	23.661194	1201	25.60408989	1154	0.980290429	0.050347963	normal	0.954537373	0.218191072	normal	0.981145464	-0.02071225	normal	0.745796906	0.079703757	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	COG4 transport protein	Conserved oligomeric Golgi complex subunit 4 GN=COG4 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: conserved oligomeric Golgi complex subunit 4 isoformX1 [Equus caballus]
ENSG00000103056(SMPD3)	--	0.220504105	23	0.273085	30	0.411739027	25	0.287295853	31	0.269044386	28	0.293181001	31	0.979187317	0.37799106	normal	0.983652422	-0.114962205	normal	0.981443338	0.286461776	normal	0.853274767	0.185056792	normal	--	--	--	"K12352|0|hsa:55512|SMPD3, NSMASE2; sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) (EC:3.1.4.12); K12352 sphingomyelin phosphodiesterase 3 [EC:3.1.4.12] (A)"	Sphingolipid metabolism (ko00600)	--	--	Endonuclease/Exonuclease/phosphatase family	Sphingomyelin phosphodiesterase 3 GN=SMPD3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: sphingomyelin phosphodiesterase 3 [Ailuropoda melanoleuca] 
ENSG00000103061(SLC7A6OS)	--	13.002042	966	14.7253165	1205	11.7622912	944	15.325425	1221	15.0238458	1174	18.241795	1453	0.897872535	0.306701144	normal	0.979889753	-0.058952336	normal	0.046161688	0.613086871	normal	0.196887235	0.283889237	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1762)	Probable RNA polymerase II nuclear localization protein SLC7A6OS GN=SLC7A6OS OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: probable RNA polymerase II nuclear localization protein SLC7A6OS [Galeopterus variegatus]
ENSG00000103064(SLC7A6)	--	23.87477302	1167	23.8287592	1269	26.788395	1225	27.7140736	1164	27.31423593	1214	27.24759386	1492	0.980888016	-0.034500286	normal	0.979013908	-0.085246328	normal	0.93124006	0.275865287	normal	0.82199263	0.059636687	normal	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13872|0|ptr:743079|SLC7A6; solute carrier family 7 (amino acid transporter light chain, y+L system), member 6; K13872 solute carrier family 7 (L-type amino acid transporter), member 6 (A)"	--	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease	Y+L amino acid transporter 2 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: Y+L amino acid transporter 2 [Galeopterus variegatus]
ENSG00000103066(PLA2G15)	--	10.71581697	530	11.90082298	548	10.54029814	521	12.11721504	525	8.442825225	432	9.475157999	448	0.971408708	-0.044377939	normal	0.812437823	-0.363438556	normal	0.938633397	-0.225369907	normal	0.385254946	-0.208412295	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: O-acyltransferase activity (GO:0008374);; 	"K06129|0|hsa:23659|PLA2G15, ACS, GXVPLA2, LLPL, LPLA2, LYPLA3; phospholipase A2, group XV (EC:2.3.1.-); K06129 lysophospholipase III [EC:3.1.1.5] (A)"	Glycerophospholipid metabolism (ko00564);; Lysosome (ko04142)	[I]	Lipid transport and metabolism	Lecithin:cholesterol acyltransferase;; Alpha/beta hydrolase family	Group XV phospholipase A2 (Precursor) GN=PLA2G15 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: group XV phospholipase A2 isoform X1 [Tupaia chinensis] 
ENSG00000103067(ESRP2)	--	0.0628382	4	0.184167336	13	0.030199607	1	0.0157553	1	0	0	0.062097307	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K14947|0|pon:100457404|ESRP2; epithelial splicing regulatory protein 2; K14947 epithelial splicing regulatory protein 1/2 (A)	--	[AR]	RNA processing and modification;; General function prediction only	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Epithelial splicing regulatory protein 2 GN=ESRP2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: epithelial splicing regulatory protein 2 isoform X1 [Condylura cristata]
ENSG00000103089(FA2H)	--	16.39354836	681	16.00048191	585	16.77769002	709	18.35623497	755	10.94280078	444	19.31931967	802	0.969268323	0.117737241	normal	0.688820628	-0.418058678	normal	0.961588464	0.169185671	normal	1	-0.00211312	normal	--	--	Molecular Function: iron ion binding (GO:0005506);; Biological Process: lipid biosynthetic process (GO:0008610);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[I]	Lipid transport and metabolism	Fatty acid hydroxylase superfamily;; Cytochrome b5-like Heme/Steroid binding domain	Fatty acid 2-hydroxylase GN=FA2H OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: fatty acid 2-hydroxylase [Oryctolagus cuniculus]
ENSG00000103091(WDR59)	--	14.71855049	1177	15.36851654	1081	14.36991428	1095	12.74621753	899	11.86210984	903	12.35188344	941	0.659119751	-0.418925656	normal	0.919772328	-0.280565073	normal	0.949702286	-0.226617719	normal	0.070464581	-0.310787746	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 59 GN=WDR59 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 59 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000103111(MON1B)	--	36.03154549	1818	25.01697204	1879	24.33754537	1903	22.74315088	1686	27.69464676	1790	32.09050671	2201	0.979069743	-0.139457497	normal	0.983276048	-0.091356694	normal	0.971570697	0.201443168	normal	0.999953667	-0.000646287	normal	--	--	--	--	--	[S]	Function unknown	Trafficking protein Mon1	Vacuolar fusion protein MON1 homolog B GN=MON1B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: vacuolar fusion protein MON1 homolog B [Galeopterus variegatus] 
ENSG00000103121(CMC2)	--	53.4258	551	58.9820543	545	77.118465	606	57.348712	527	54.3301416	479	58.7213336	567	0.968314389	-0.09481125	normal	0.945355834	-0.207043805	normal	0.968470541	-0.103992152	normal	0.607052513	-0.134543205	normal	--	--	--	K18172|1.39225e-25|ptr:454264|CMC2; C-x(9)-C motif containing 2; K18172 COX assembly mitochondrial protein 2 (A)	--	[S]	Function unknown	Cytochrome c oxidase biogenesis protein Cmc1 like	COX assembly mitochondrial protein 2 homolog GN=CMC2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COX assembly mitochondrial protein 2 homolog isoform X1 [Oryctolagus cuniculus]
ENSG00000103126(AXIN1)	--	19.23684786	1269	19.25199937	1233	18.60082081	1203	14.7029143	960	15.02584557	945	14.88098495	950	0.610522847	-0.432813289	normal	0.720275254	-0.404644373	normal	0.841334574	-0.348434566	normal	0.012970016	-0.397268139	normal	--	--	--	"K02157|0|hsa:8312|AXIN1, AXIN, PPP1R49; axin 1; K02157 axin 1 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	DIX domain;; Regulator of G protein signaling domain;; Axin beta-catenin binding domain	Axin-1 GN=AXIN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: axin-1 isoform X1 [Pteropus alecto] 
ENSG00000103145(HCFC1R1)	--	172.9464594	1325	140.5727382	998	159.533751	1259	109.44134	827	123.4444652	1015	170.2248422	1331	0.004782514	-0.709813047	normal	0.979158889	0.002937036	normal	0.980746398	0.071856892	normal	0.633530087	-0.194473551	normal	--	--	--	--	--	--	--	HCF-1 beta-propeller-interacting protein family	Host cell factor C1 regulator 1 GN=HCFC1R1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: host cell factor C1 regulator 1 isoform X1 [Physeter catodon]
ENSG00000103148(NPRL3)	--	20.03335225	966	19.48898394	896	20.94912225	1023	14.272711	664	16.68512623	791	20.19018723	944	0.121046318	-0.570570506	normal	0.954804679	-0.20088645	normal	0.972911337	-0.124047867	normal	0.168492753	-0.286074835	normal	--	--	--	--	--	[S]	Function unknown	Nitrogen Permease regulator of amino acid transport activity 3	Nitrogen permease regulator 3-like protein GN=NPRL3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nitrogen permease regulator 3-like protein isoformX1 [Canis lupus familiaris]
ENSG00000103150(MLYCD)	--	24.95478794	1217	41.530019	1683	22.049631	1120	11.40707397	736	11.253389	798	23.57862199	1190	0.001589219	-0.755143839	normal	2.53E-08	-1.096535514	down	0.978970363	0.079067812	normal	0.157281006	-0.581730384	normal	[G]	Carbohydrate transport and metabolism	Biological Process: fatty acid biosynthetic process (GO:0006633);; Molecular Function: malonyl-CoA decarboxylase activity (GO:0050080);; 	"K01578|0|hsa:23417|MLYCD, MCD; malonyl-CoA decarboxylase (EC:4.1.1.9); K01578 malonyl-CoA decarboxylase [EC:4.1.1.9] (A)"	beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Peroxisome (ko04146);; AMPK signaling pathway (ko04152)	[G]	Carbohydrate transport and metabolism	Malonyl-CoA decarboxylase (MCD)	"Malonyl-CoA decarboxylase, mitochondrial (Precursor) GN=MLYCD OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: malonyl-CoA decarboxylase, mitochondrial isoform 1 [Dasypus novemcinctus]"
ENSG00000103152(MPG)	--	47.51845	932	38.36030331	763	47.15216022	961	46.83232	927	46.97859531	923	40.04017	800	0.978131519	-0.038529192	normal	0.933494333	0.252764962	normal	0.921921543	-0.272357427	normal	0.941274756	-0.024583674	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: alkylbase DNA N-glycosylase activity (GO:0003905);; Biological Process: base-excision repair (GO:0006284);; 	"K03652|0|hsa:4350|MPG, AAG, ADPG, APNG, CRA36.1, MDG, Mid1, PIG11, PIG16, anpg; N-methylpurine-DNA glycosylase (EC:3.2.2.21); K03652 DNA-3-methyladenine glycosylase [EC:3.2.2.21] (A)"	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	Methylpurine-DNA glycosylase (MPG)	DNA-3-methyladenine glycosylase (Precursor) GN=MPG OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	hypothetical protein PANDA_008906 [Ailuropoda melanoleuca]
ENSG00000103154(NECAB2)	--	0.720015617	24	2.119121975	41	2.731155	35	1.345379135	18	0.4658012	14	1.033689683	24	0.982856122	-0.415081694	normal	0.147869911	-1.474469658	normal	0.964524677	-0.525063776	normal	0.179151698	-0.85686338	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	Antibiotic biosynthesis monooxygenase;; EF-hand domain pair;; EF hand;; EF-hand domain pair;; EF hand;; EF-hand domain	N-terminal EF-hand calcium-binding protein 2 GN=NECAB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: N-terminal EF-hand calcium-binding protein 2 [Lipotes vexillifer]
ENSG00000103160(HSDL1)	--	14.92657517	818	14.4691818	789	13.28979153	730	12.0800006	664	11.31601656	623	13.56187575	743	0.858057096	-0.331058196	normal	0.812865741	-0.36143805	normal	0.975953553	0.017139111	normal	0.27284134	-0.224226117	normal	[R]	General function prediction only	--	--	--	[I]	Lipid transport and metabolism	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; NADH(P)-binding;; KR domain	Inactive hydroxysteroid dehydrogenase-like protein 1 GN=HSDL1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: inactive hydroxysteroid dehydrogenase-like protein 1 [Galeopterus variegatus]
ENSG00000103168(TAF1C)	--	10.18919782	668	9.122670309	577	10.16074965	713	8.589762252	530	10.67826223	604	9.790260202	669	0.80346515	-0.363746281	normal	0.97200311	0.044436838	normal	0.970854197	-0.099968368	normal	0.572601912	-0.139178258	normal	--	--	--	"K15214|0|ptr:454279|TAF1C; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; K15214 TATA box-binding protein-associated factor RNA polymerase I subunit C (A)"	--	--	--	--	TATA box-binding protein-associated factor RNA polymerase I subunit C GN=TAF1C OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: TATA box-binding protein-associated factor RNA polymerase I subunit C isoform X1 [Vicugna pacos]
ENSG00000103174(NAGPA)	--	9.14223714	352	10.22262959	402	9.762235517	399	8.607810106	342	9.3482958	368	10.93109704	435	0.966301624	-0.072092103	normal	0.957313624	-0.148332828	normal	0.963645433	0.115914335	normal	0.941274756	-0.030436722	normal	--	--	--	"K01125|0|hsa:51172|NAGPA, APAA, UCE; N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (EC:3.1.4.45); K01125 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase [EC:3.1.4.45] (A)"	Lysosome (ko04142)	--	--	Predicted periplasmic protein (DUF2233)	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (Precursor) GN=NAGPA OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase isoform X2 [Canis lupus familiaris]
ENSG00000103184(SEC14L5)	--	0.0471931	6	0.0693968	9	0.0152553	1	0.00788683	1	0.0459836	5	0.00781454	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	"PRELI-like family;; CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain"	SEC14-like protein 5 GN=SEC14L5 OS=Homo sapiens (Human) PE=2 SV=3	I	Lipid transport and metabolism	PREDICTED: SEC14-like protein 5 isoform X1 [Panthera tigris altaica]
ENSG00000103187(COTL1)	--	284.34746	8808	314.5432743	9892	317.3903874	10017	332.725851	10380	256.619888	7953	242.151635	7568	0.990534036	0.206054669	normal	0.958187744	-0.336132188	normal	0.866586741	-0.412686024	normal	0.479153582	-0.171035308	normal	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	--	--	[Z]	Cytoskeleton	Cofilin/tropomyosin-type actin-binding protein	Coactosin-like protein GN=COTL1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: coactosin-like protein [Equus caballus] 
ENSG00000103194(USP10)	--	37.08455	2013	36.76730306	2026	33.53500603	1948	38.47741642	2184	36.94973	2143	35.27022091	2052	0.985281906	0.08672986	normal	0.985996745	0.059527912	normal	0.985692595	0.066695159	normal	0.771863419	0.070063113	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11841|0|hsa:9100|USP10, UBPO; ubiquitin specific peptidase 10 (EC:3.4.19.12); K11841 ubiquitin carboxyl-terminal hydrolase 10 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Ataxin-2 C-terminal region	Ubiquitin carboxyl-terminal hydrolase 10 GN=USP10 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 10 [Ursus maritimus]
ENSG00000103196(CRISPLD2)	--	1.709386746	151	1.900664611	168	2.21195519	161	4.825824245	407	3.716462197	314	1.691386218	144	1.66E-09	1.390691596	up	0.003297876	0.875026696	normal	0.957725128	-0.167617597	normal	0.254312962	0.825752458	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	LCCL domain;; Cysteine-rich secretory protein family	Cysteine-rich secretory protein LCCL domain-containing 2 (Precursor) GN=UNQ2914/PRO1156/PRO9783 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cysteine-rich secretory protein LCCL domain-containing 2 [Pteropus alecto]
ENSG00000103197(TSC2)	--	12.84491248	1314	12.276364	1325	12.60194102	1338	11.50979101	1170	12.58943536	1354	13.73773827	1505	0.962955011	-0.198043418	normal	0.982403479	0.009797759	normal	0.973115404	0.161222025	normal	0.99787031	-0.001652007	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: positive regulation of GTPase activity (GO:0043547);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	"K07207|0|hsa:7249|TSC2, LAM, PPP1R160, TSC4; tuberous sclerosis 2; K07207 tuberous sclerosis 2 (A)"	p53 signaling pathway (ko04115);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Thyroid hormone signaling pathway (ko04919);; Choline metabolism in cancer (ko05231)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	Tuberin;; Domain of unknown function (DUF3384);; Rap/ran-GAP	Tuberin GN=TSC2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tuberin isoform 1 [Ceratotherium simum simum]
ENSG00000103199(ZNF500)	--	3.8521616	308	4.119797001	334	4.14894	371	5.198393	306	6.409220006	329	5.06636	352	0.967229767	-0.040030619	normal	0.966651052	-0.042990946	normal	0.965812724	-0.083784529	normal	0.881323279	-0.058020743	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:26048|ZNF500, ZKSCAN18, ZSCAN50; zinc finger protein 500; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; KRAB box"	Zinc finger protein 500 GN=ZNF500 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 500 isoform X2 [Tupaia chinensis]
ENSG00000103202(NME4)	--	250.2185263	4242	236.2037128	4061	244.6110194	4259	158.4913684	2742	169.9248169	2863	133.1649405	2273	0.015179298	-0.660048369	normal	0.313018464	-0.525499564	normal	5.29E-06	-0.913756897	normal	6.99E-07	-0.694772819	normal	[F]	Nucleotide transport and metabolism	--	K00940|4.81499e-129|ptr:100611890|NME4; NME/NM23 nucleoside diphosphate kinase 4; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Nucleoside diphosphate kinase	"Nucleoside diphosphate kinase, mitochondrial (Precursor) GN=NME4 OS=Homo sapiens (Human) PE=1 SV=1"	F	Nucleotide transport and metabolism	"PREDICTED: nucleoside diphosphate kinase, mitochondrial [Ceratotherium simum simum]"
ENSG00000103222(ABCC1)	--	57.20923471	7679	61.1890885	8246	60.55373101	8166	52.80911102	7080	54.94211716	7345	57.03700075	7678	0.992416127	-0.147970505	normal	0.990186339	-0.188321909	normal	0.994449548	-0.097171887	normal	0.5083059	-0.145160434	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05665|0|hsa:4363|ABCC1, ABC29, ABCC, GS-X, MRP, MRP1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; K05665 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 (A)"	ABC transporters (ko02010);; Sphingolipid signaling pathway (ko04071);; Vitamin digestion and absorption (ko04977);; MicroRNAs in cancer (ko05206)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter transmembrane region;; ABC transporter;; AAA domain;; 50S ribosome-binding GTPase;; Miro-like protein;; Predicted ATPase of the ABC class	Multidrug resistance-associated protein 1 GN=ABCC1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: multidrug resistance-associated protein 1 [Odobenus rosmarus divergens]
ENSG00000103226(NOMO3)	--	7.122027532	379	4.092971772	341	2.828034497	236	4.018915825	331	3.245317287	267	2.32309821	192	0.937306577	-0.225220941	normal	0.821666386	-0.372486552	normal	0.907963442	-0.303809621	normal	0.55036007	-0.298617075	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Carboxypeptidase regulatory-like domain;; Domain of unknown function (DUF4480);; Protein of unknown function (DUF2012);; Cna protein B-type domain;; Polysaccharide lyase family 4, domain II;; Protein of unknown function (DUF1416);; Y_Y_Y domain"	Nodal modulator 2 (Precursor) GN=NOMO2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nodal modulator 1 [Galeopterus variegatus]
ENSG00000103227(LMF1)	--	9.556239277	374	7.312547772	321	7.232187128	359	5.705342542	245	7.672813799	303	8.505229787	376	0.108022831	-0.637825042	normal	0.962086125	-0.104176802	normal	0.967623889	0.058217726	normal	0.487577431	-0.209717538	normal	--	--	--	--	--	--	--	Lipase maturation factor	Lipase maturation factor 1 GN=LMF1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lipase maturation factor 1 [Galeopterus variegatus]
ENSG00000103245(NARFL)	--	12.63814256	506	9.74277073	392	12.52102599	515	11.98640772	485	11.5227795	459	12.718331	516	0.967715462	-0.091700455	normal	0.944211329	0.205480759	normal	0.972137122	-0.005476742	normal	0.949678474	0.026476124	normal	[R]	General function prediction only	--	--	--	[Y]	Nuclear structure	"Iron only hydrogenase large subunit, C-terminal domain;; Iron hydrogenase small subunit"	Cytosolic Fe-S cluster assembly factor NARFL GN=NARFL OS=Homo sapiens (Human) PE=1 SV=1	Y	Nuclear structure	PREDICTED: cytosolic Fe-S cluster assembly factor NARFL isoform X1 [Galeopterus variegatus]
ENSG00000103248(MTHFSD)	--	7.656848344	309	6.89801629	224	7.787208578	258	6.511444207	300	7.790976167	309	7.37674212	318	0.965527357	-0.073107648	normal	0.713070021	0.440141772	normal	0.905836103	0.291820902	normal	0.494966685	0.207895026	normal	--	--	--	--	--	[H]	Coenzyme transport and metabolism	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Methenyltetrahydrofolate synthase domain-containing protein GN=MTHFSD OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: methenyltetrahydrofolate synthase domain-containing protein isoform X2 [Galeopterus variegatus]
ENSG00000103249(CLCN7)	--	25.57487774	2151	33.995663	2887	25.23144376	2172	27.413858	2308	26.17696137	2187	44.3998413	3747	0.986579468	0.070754642	normal	0.728306535	-0.421789693	normal	0.000511626	0.778002994	normal	0.785695034	0.172935443	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05016|0|hsa:1186|CLCN7, CLC-7, CLC7, OPTA2, OPTB4, PPP1R63; chloride channel, voltage-sensitive 7; K05016 chloride channel 7 (A)"	--	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel	H(+)/Cl(-) exchange transporter 7 GN=CLCN7 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: H(+)/Cl(-) exchange transporter 7 isoform X2 [Eptesicus fuscus]
ENSG00000103253(HAGHL)	--	14.14001837	276	12.81001425	244	12.38302952	240	11.66572794	239	13.2456263	251	13.43384825	257	0.934966554	-0.237070155	normal	0.965921077	0.019261954	normal	0.963790624	0.089895034	normal	0.918663533	-0.045963653	normal	[R]	General function prediction only	--	K01069|1.2392e-143|hsa:84264|HAGHL; hydroxyacylglutathione hydrolase-like (EC:3.1.2.6); K01069 hydroxyacylglutathione hydrolase [EC:3.1.2.6] (A)	Pyruvate metabolism (ko00620)	[R]	General function prediction only	Metallo-beta-lactamase superfamily	Hydroxyacylglutathione hydrolase-like protein GN=HAGHL OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: hydroxyacylglutathione hydrolase-like protein [Ceratotherium simum simum]
ENSG00000103254(FAM173A)	--	41.522629	523	40.124103	538	33.07442	437	30.75549	410	36.95594	468	37.351379	481	0.777293002	-0.380752344	normal	0.939809717	-0.221854924	normal	0.962646208	0.129684262	normal	0.539907804	-0.161514571	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[S]	Function unknown	Methyltransferase domain	Protein FAM173A GN=FAM173A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM173A [Vicugna pacos]
ENSG00000103257(SLC7A5)	--	345.342515	27549	392.8075092	31656	385.1520317	31182	445.382511	35262	381.152221	30307	586.59535	47029	0.986404292	0.325266022	normal	0.998239451	-0.084250363	normal	0.358065934	0.584522507	normal	0.39482408	0.296688644	normal	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13780|0|hsa:8140|SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1; solute carrier family 7 (amino acid transporter light chain, L system), member 5; K13780 solute carrier family 7 (L-type amino acid transporter), member 5 (A)"	Central carbon metabolism in cancer (ko05230)	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease	Large neutral amino acids transporter small subunit 1 GN=SLC7A5 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: large neutral amino acids transporter small subunit 1 [Galeopterus variegatus]
ENSG00000103260(METRN)	--	107.6252368	2859	108.8535919	3088	109.8440802	3048	93.15333	2498	101.4134905	2658	95.73601058	2688	0.970763961	-0.225439667	normal	0.968993974	-0.237632631	normal	0.979221425	-0.189521004	normal	0.21844182	-0.218455488	normal	--	--	--	--	--	--	--	--	Meteorin (Precursor) GN=METRN OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: meteorin [Orcinus orca]
ENSG00000103264(FBXO31)	--	13.10235426	777	11.74658607	654	13.42549105	800	12.2153387	822	12.87699616	811	13.12311431	810	0.975900214	0.050294837	normal	0.906520058	0.288384903	normal	0.977066443	0.009612408	normal	0.656178816	0.109968779	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10308|0|ggo:101130488|FBXO31; F-box only protein 31; K10308 F-box protein 31 (A)	--	--	--	F-box-like;; F-box domain	F-box only protein 31 GN=FBXO31 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box only protein 31 [Erinaceus europaeus]
ENSG00000103266(STUB1)	--	43.08261001	1142	37.80450106	1004	38.731062	1140	42.093096	1160	43.693624	1155	38.91481285	1068	0.981135846	-0.008259084	normal	0.964519667	0.180453445	normal	0.976701953	-0.102273419	normal	0.950458395	0.020690839	normal	[R]	General function prediction only	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein ubiquitination (GO:0016567);; 	"K09561|0|pps:100972088|STUB1; STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase; K09561 STIP1 homology and U-box containing protein 1 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	"U-box domain;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	E3 ubiquitin-protein ligase CHIP {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase CHIP [Galeopterus variegatus]
ENSG00000103269(RHBDL1)	--	1.587053822	38	1.314552129	33	1.888659035	45	0.93613	21	1.369564	31	0.617621642	15	0.880455795	-0.840104683	normal	0.982537068	-0.106583848	normal	0.082823387	-1.501848843	normal	0.181624881	-0.813140749	normal	[R]	General function prediction only	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	"K02857|0|pon:100442110|RHBDL1; rhomboid, veinlet-like 1 (Drosophila); K02857 rhomboid-related protein 1/2/3 [EC:3.4.21.105] (A)"	--	[T]	Signal transduction mechanisms	Rhomboid family	Rhomboid-related protein 1 GN=RHBDL1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: rhomboid-related protein 1 isoform X3 [Galeopterus variegatus]
ENSG00000103274(NUBP1)	--	9.6029576	233	10.761902	265	8.852345	217	12.52563828	306	17.87790682	417	13.207516	312	0.846237584	0.36029096	normal	0.115582162	0.629740871	normal	0.506259636	0.512564825	normal	0.041003114	0.512371539	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	ParA/MinD ATPase like;; CobQ/CobB/MinD/ParA nucleotide binding domain;; AAA domain;; Anion-transporting ATPase;; ATPase MipZ	Cytosolic Fe-S cluster assembly factor NUBP1 {ECO:0000255|HAMAP-Rule:MF_03038} OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cytosolic Fe-S cluster assembly factor NUBP1 [Pteropus alecto] 
ENSG00000103275(UBE2I)	--	62.86301967	2212	57.38958825	2183	65.55411038	2381	83.60838852	2863	74.54825495	2704	65.30435013	2360	0.89502838	0.341135266	normal	0.94403349	0.287177419	normal	0.988275774	-0.021058768	normal	0.25505784	0.204740284	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10577|5.79776e-110|mcf:102142834|UBE2I; ubiquitin-conjugating enzyme E2I; K10577 ubiquitin-conjugating enzyme E2 I [EC:6.3.2.19] (A)	RNA transport (ko03013);; NF-kappa B signaling pathway (ko04064);; Ubiquitin mediated proteolysis (ko04120);; MicroRNAs in cancer (ko05206)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	SUMO-conjugating enzyme UBC9 GN=UBE2I OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	hypothetical protein PANDA_008958 [Ailuropoda melanoleuca]
ENSG00000103313(MEFV)	--	0	0	0	0	0	0	0.013395	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	"K12803|0|hsa:4210|MEFV, FMF, MEF, TRIM20; Mediterranean fever; K12803 pyrin (A)"	NOD-like receptor signaling pathway (ko04621)	[O]	"Posttranslational modification, protein turnover, chaperones"	PAAD/DAPIN/Pyrin domain;; SPRY domain;; SPRY-associated domain;; B-box zinc finger	Pyrin GN=MEFV OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: pyrin [Galeopterus variegatus]
ENSG00000103316(CRYM)	--	0.763208454	20	0.478489294	12	0.687658324	18	1.541092497	23	1.017964467	21	1.097594288	16	0.987769446	0.159378777	normal	0.97262599	0.716933044	normal	--	--	--	0.827714025	0.241132894	normal	[E]	Amino acid transport and metabolism	--	"K18258|0|hsa:1428|CRYM, DFNA40, THBP; crystallin, mu (EC:1.5.1.25); K18258 thiomorpholine-carboxylate dehydrogenase [EC:1.5.1.25] (A)"	--	[E]	Amino acid transport and metabolism	Ornithine cyclodeaminase/mu-crystallin family;; Shikimate / quinate 5-dehydrogenase;; NADP oxidoreductase coenzyme F420-dependent;; NAD binding domain of 6-phosphogluconate dehydrogenase	Ketimine reductase mu-crystallin GN=CRYM OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: ketimine reductase mu-crystallin [Oryctolagus cuniculus]
ENSG00000103319(EEF2K)	--	6.890966056	959	6.375934985	887	6.649025935	924	6.599175095	918	6.123627563	850	5.905134071	825	0.975236226	-0.093715443	normal	0.974613261	-0.082753676	normal	0.963358836	-0.171492959	normal	0.620426589	-0.116771221	normal	--	--	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08292|0|hsa:29904|EEF2K, HSU93850, eEF-2K; eukaryotic elongation factor 2 kinase (EC:2.7.11.20); K08292 elongation factor 2 kinase [EC:2.7.11.20] (A)"	AMPK signaling pathway (ko04152);; Oxytocin signaling pathway (ko04921)	--	--	Alpha-kinase family;; Sel1 repeat	Eukaryotic elongation factor 2 kinase GN=EEF2K OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic elongation factor 2 kinase [Ursus maritimus] 
ENSG00000103326(CAPN15)	--	15.66095723	1590	13.4079485	1529	16.6498379	1756	20.02303322	2194	18.09661737	1903	18.19496633	1954	0.641204256	0.433346687	normal	0.927220512	0.293999503	normal	0.979140096	0.145727157	normal	0.077408399	0.290405274	normal	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K08582|0|hsa:6650|CAPN15, SOLH; calpain 15; K08582 calpain-15 [EC:3.4.22.-] (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Calpain family cysteine protease;; Zn-finger in Ran binding protein and others	Calpain-15 GN=CAPN15 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-15 [Galeopterus variegatus]
ENSG00000103335(PIEZO1)	--	25.93660389	3628	24.4446554	3502	25.56442	3756	40.045212	5221	36.50390366	4860	35.00814628	4904	0.466125895	0.494144146	normal	0.682277284	0.45118461	normal	0.877089315	0.376337489	normal	0.003925005	0.439747957	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF3595)	Piezo-type mechanosensitive ion channel component 1 GN=PIEZO1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: piezo-type mechanosensitive ion channel component 1 [Eptesicus fuscus]
ENSG00000103342(GSPT1)	--	77.42121013	4485	68.31055109	4084	73.56778567	4356	82.6110895	5301	78.44601418	4960	75.41847113	4589	0.983337436	0.210257982	normal	0.972166262	0.258843608	normal	0.992107884	0.066861793	normal	0.357941178	0.178725257	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K03267|0|ggo:101138927|GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform 1; K03267 peptide chain release factor subunit 3 (A)	mRNA surveillance pathway (ko03015)	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2;; Ataxin-2 C-terminal region;; 50S ribosome-binding GTPase	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B GN=GSPT2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1 [Ochotona princeps]
ENSG00000103343(ZNF174)	--	7.799469	233	8.44472177	239	7.743866633	223	8.75763	275	10.58234877	280	8.012863088	235	0.944728869	0.20701185	normal	0.943785991	0.205785646	normal	0.965255562	0.066883723	normal	0.638639343	0.163132309	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09230|0|nle:100590646|ZNF174; zinc finger protein 174; K09230 SCAN domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"SCAN domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein 174 GN=ZNF174 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 174 [Galeopterus variegatus] 
ENSG00000103351(CLUAP1)	--	5.229013	366	6.2758619	344	11.415982	381	10.1901903	424	6.2614172	338	5.452163	328	0.95143919	0.180683205	normal	0.966695618	-0.046605177	normal	0.938205978	-0.223429853	normal	0.961743152	-0.023226526	normal	--	--	--	--	--	[R]	General function prediction only	Clusterin-associated protein-1	Clusterin-associated protein 1 GN=CLUAP1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: clusterin-associated protein 1 isoform X4 [Equus przewalskii]
ENSG00000103353(UBFD1)	--	30.94898	1970	34.7341	1952	36.6888	2139	34.9865	2482	33.16436	2249	28.57748	2032	0.9287421	0.30226482	normal	0.975433126	0.182772046	normal	0.985456016	-0.082267839	normal	0.504598307	0.136470667	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin family;; Ubiquitin-like domain	Ubiquitin domain-containing protein UBFD1 GN=UBFD1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin domain-containing protein UBFD1 [Odobenus rosmarus divergens] 
ENSG00000103356(EARS2)	--	30.12232238	2808	29.7480636	2751	32.178756	2865	26.804243	2420	27.4653105	2460	25.49818303	2291	0.964343738	-0.245223448	normal	0.978747364	-0.182618153	normal	0.908562627	-0.330653517	normal	0.136926856	-0.253600082	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: ATP binding (GO:0005524);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	"K01885|0|hsa:124454|EARS2, COXPD12, MSE1; glutamyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.17); K01885 glutamyl-tRNA synthetase [EC:6.1.1.17] (A)"	Porphyrin and chlorophyll metabolism (ko00860);; Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (E and Q), catalytic domain"	"Probable glutamate--tRNA ligase, mitochondrial (Precursor) GN=EARS2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable glutamate--tRNA ligase, mitochondrial [Physeter catodon]"
ENSG00000103363(ELOB)	--	154.771146	1613	156.6656967	1766	182.632371	1945	169.941754	1798	168.000943	1723	175.922974	1924	0.980125392	0.125700879	normal	0.98428639	-0.056939833	normal	0.986430843	-0.023934087	normal	0.974305101	0.011650752	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03873|8.34949e-106|nle:100584170|transcription elongation factor B polypeptide 2-like; K03873 transcription elongation factor B, polypeptide 2 (A)"	HIF-1 signaling pathway (ko04066);; Ubiquitin mediated proteolysis (ko04120);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[K]	Transcription	Ubiquitin family	Transcription elongation factor B polypeptide 2 GN=TCEB2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription elongation factor B polypeptide 2 isoform X1 [Felis catus] 
ENSG00000103375(AQP8)	--	0	0	0	0	0	0	0	0	0	0	0.050202295	1	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K09869|4.59698e-152|hsa:343|AQP8, AQP-8; aquaporin 8; K09869 aquaporin-8 (A)"	Bile secretion (ko04976)	[G]	Carbohydrate transport and metabolism	Major intrinsic protein	Aquaporin-8 GN=AQP8 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-8 [Tupaia chinensis]
ENSG00000103381(CPPED1)	--	11.65228	744	12.78277	859	12.95059	814	26.68763	1603	23.94635	1532	20.39543	1318	3.95E-08	1.075020007	up	0.0003703	0.812174861	normal	0.009023052	0.685947262	normal	9.28E-10	0.859810564	normal	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[G]	Carbohydrate transport and metabolism	Calcineurin-like phosphoesterase;; Calcineurin-like phosphoesterase superfamily domain	Serine/threonine-protein phosphatase CPPED1 GN=CPPED1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: serine/threonine-protein phosphatase CPPED1 [Loxodonta africana]
ENSG00000103404(USP31)	--	6.231045501	863	6.559833	959	6.473651974	866	7.872236699	1043	9.442744	1254	7.7155262	1071	0.941215074	0.242081942	normal	0.817468063	0.365003386	normal	0.903556455	0.297759709	normal	0.078896627	0.304225599	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11852|0|hsa:57478|USP31; ubiquitin specific peptidase 31 (EC:3.4.19.12); K11852 ubiquitin carboxyl-terminal hydrolase 31 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 31 GN=USP31 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 31 [Canis lupus familiaris]
ENSG00000103415(HMOX2)	--	19.7296493	620	17.813255	621	19.835418	651	20.91324934	722	21.6291801	656	15.86722039	568	0.954876734	0.188465269	normal	0.972323211	0.057539649	normal	0.948869128	-0.204548925	normal	0.959389613	0.01878412	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: heme oxygenase (decyclizing) activity (GO:0004392);; Biological Process: heme oxidation (GO:0006788);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00510|0|ptr:453880|HMOX2; heme oxygenase (decycling) 2; K00510 heme oxygenase [EC:1.14.99.3] (A)	Porphyrin and chlorophyll metabolism (ko00860);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Heme oxygenase;; Putative binding domain	Heme oxygenase 2 GN=HMOX2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: heme oxygenase 2 [Tupaia chinensis] 
ENSG00000103423(DNAJA3)	--	32.07184889	1670	32.80968688	1741	35.805393	1892	31.28642347	1654	33.99925626	1765	31.45268927	1657	0.984512993	-0.044679826	normal	0.98525973	-0.001673134	normal	0.969401848	-0.199459433	normal	0.718515576	-0.084083226	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: heat shock protein binding (GO:0031072);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K09504|0|ptr:453879|DNAJA3; DnaJ (Hsp40) homolog, subfamily A, member 3; K09504 DnaJ homolog subfamily A member 3 (A)"	Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain;; DnaJ central domain	"DnaJ homolog subfamily A member 3, mitochondrial (Precursor) GN=DNAJA3 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: dnaJ homolog subfamily A member 3, mitochondrial [Galeopterus variegatus]"
ENSG00000103426(CORO7-PAM16)	--	48.78891356	682	42.92755541	664	51.08387	609	38.55592922	615	37.2567806	705	30.95610305	534	0.956764281	-0.17959127	normal	0.972762714	0.064870066	normal	0.95033311	-0.197370118	normal	0.719802572	-0.098177297	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K18619|0|hsa:100529144|CORO7-PAM16; CORO7-PAM16 readthrough; K18619 coronin-7 (A)	--	[Z]	Cytoskeleton	"Domain of unknown function (DUF1900);; Pam16;; WD domain, G-beta repeat;; Domain of unknown function (DUF1899)"	Coronin-7 GN=CORO7 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: coronin-7 [Camelus bactrianus]
ENSG00000103429(BFAR)	--	40.9512757	1780	39.29840873	1872	39.37874391	1781	35.51603131	1698	36.48599177	1604	39.6584824	1824	0.982549004	-0.098785728	normal	0.955298268	-0.244119552	normal	0.98572541	0.026104867	normal	0.632646487	-0.104975689	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K15684|0|hsa:51283|BFAR, BAR, RNF47; bifunctional apoptosis regulator; K15684 bifunctional apoptosis regulator (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"zinc finger of C3HC4-type, RING;; SAM domain (Sterile alpha motif);; Zinc finger, C3HC4 type (RING finger);; SAM domain (Sterile alpha motif)"	Bifunctional apoptosis regulator GN=BFAR OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: bifunctional apoptosis regulator isoform X1 [Tupaia chinensis] 
ENSG00000103449(SALL1)	--	2.298455	238	1.65399892	150	2.071152494	209	0.92027043	66	0.78440869	80	0.940459754	60	3.24E-12	-1.856889208	down	0.032389935	-0.915466197	normal	1.86E-10	-1.783117635	down	3.60E-06	-1.556187214	down	[R]	General function prediction only	--	--	--	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger;; C2H2 type zinc-finger (2 copies)"	Sal-like protein 1 GN=SALL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: sal-like protein 1 [Tupaia chinensis]
ENSG00000103460(TOX3)	--	0.095951505	6	0	0	0.15730199	2	2.580242649	154	2.21653621	117	0.973151612	51	0	4.339684597	up	0	6.281621098	up	4.73E-09	3.895785845	up	3.90E-06	5.306665683	up	--	--	--	--	--	[R]	General function prediction only	HMG (high mobility group) box;; HMG-box domain	TOX high mobility group box family member 3 GN=TOX3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: TOX high mobility group box family member 3-like isoform X1 [Chrysochloris asiatica]
ENSG00000103479(RBL2)	--	17.1232603	1553	14.31940377	1298	15.2590651	1366	14.96757885	1360	14.78484472	1334	15.06260583	1367	0.958992068	-0.222048466	normal	0.982132871	0.018021015	normal	0.983081089	-0.007227684	normal	0.755536218	-0.075599285	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of cell cycle (GO:0051726);; 	"K16332|0|hsa:5934|RBL2, P130, Rb2; retinoblastoma-like 2; K16332 retinoblastoma-like protein 2 (A)"	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; PI3K-Akt signaling pathway (ko04151);; Viral carcinogenesis (ko05203)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Retinoblastoma-associated protein A domain;; Retinoblastoma-associated protein B domain;; Domain of unknown function (DUF3452)	Retinoblastoma-like protein 2 GN=RBL2 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: retinoblastoma-like protein 2 [Ceratotherium simum simum]
ENSG00000103485(QPRT)	--	3.007779	71	2.1068152	47	2.3511543	62	0.2684269	7	2.340512	26	0.4092942	9	5.61E-10	-3.114727265	down	0.800750765	-0.838777853	normal	6.44E-07	-2.602555419	down	1.21E-05	-2.119470795	down	[H]	Coenzyme transport and metabolism	"Molecular Function: nicotinate-nucleotide diphosphorylase (carboxylating) activity (GO:0004514);; Biological Process: NAD biosynthetic process (GO:0009435);; Molecular Function: transferase activity, transferring pentosyl groups (GO:0016763);; "	"K00767|0|hsa:23475|QPRT, HEL-S-90n, QPRTase; quinolinate phosphoribosyltransferase (EC:2.4.2.19); K00767 nicotinate-nucleotide pyrophosphorylase (carboxylating) [EC:2.4.2.19] (A)"	Nicotinate and nicotinamide metabolism (ko00760)	[F]	Nucleotide transport and metabolism	"Quinolinate phosphoribosyl transferase, C-terminal domain;; Quinolinate phosphoribosyl transferase, N-terminal domain"	Nicotinate-nucleotide pyrophosphorylase [carboxylating] GN=QPRT OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: nicotinate-nucleotide pyrophosphorylase [carboxylating] [Canis lupus familiaris]
ENSG00000103489(XYLT1)	--	0.256646973	34	0.066188292	13	0.025179315	4	0.980649664	152	1.57724897	235	0.882763	135	1.27E-10	2.081197459	up	0	4.0063268	up	0	4.623127894	up	4.61E-08	3.332466874	up	--	--	Biological Process: glycosaminoglycan biosynthetic process (GO:0006024);; Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; Molecular Function: protein xylosyltransferase activity (GO:0030158);; 	"K00771|0|hsa:64131|XYLT1, DBQD2, PXYLT1, XT-I, XT1, XTI, XYLTI; xylosyltransferase I (EC:2.4.2.26); K00771 protein xylosyltransferase [EC:2.4.2.26] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532);; Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[G]	Carbohydrate transport and metabolism	Xylosyltransferase C terminal;; Core-2/I-Branching enzyme	Xylosyltransferase 1 GN=XYLT1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	"PREDICTED: xylosyltransferase 1-like, partial [Tupaia chinensis]"
ENSG00000103490(PYCARD)	--	18.972469	225	18.71686993	230	21.85518714	267	24.52158042	291	25.00605573	305	22.09949995	277	0.872790721	0.338226412	normal	0.816502759	0.38355242	normal	0.966632773	0.044507286	normal	0.393709563	0.252976552	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K12799|1.41463e-115|hsa:29108|PYCARD, ASC, CARD5, TMS, TMS-1, TMS1; PYD and CARD domain containing; K12799 apoptosis-associated speck-like protein containing a CARD (A)"	NOD-like receptor signaling pathway (ko04621);; Cytosolic DNA-sensing pathway (ko04623);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Influenza A (ko05164)	--	--	Caspase recruitment domain;; PAAD/DAPIN/Pyrin domain	Apoptosis-associated speck-like protein containing a CARD GN=PYCARD OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: apoptosis-associated speck-like protein containing a CARD isoform 1 [Trichechus manatus latirostris]
ENSG00000103494(RPGRIP1L)	--	8.430139388	606	6.49212713	553	10.47551852	705	7.717763014	597	7.235909519	482	6.5478546	457	0.972490763	-0.052285563	normal	0.941195078	-0.219030708	normal	0.050523314	-0.632023149	normal	0.16070926	-0.300908292	normal	--	--	--	K16550|0|pon:100444540|RPGRIP1L; RPGRIP1-like; K16550 protein fantom (A)	--	--	--	Protein of unknown function (DUF3250);; C2 domain	Protein fantom GN=RPGRIP1L OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	Protein fantom [Bos mutus]
ENSG00000103495(MAZ)	--	60.71667395	2478	78.449519	3233	60.70818417	2596	64.5468977	2629	66.36532586	2692	74.8781012	3106	0.988314548	0.054472899	normal	0.951138183	-0.285475081	normal	0.96457648	0.250342511	normal	1	-0.000230238	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Myc-associated zinc finger protein GN=MAZ OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myc-associated zinc finger protein isoform X1 [Eptesicus fuscus]
ENSG00000103496(STX4)	--	24.85371877	790	21.26696791	724	24.77803218	856	24.26493598	852	25.11319504	857	24.10282361	803	0.974701577	0.078022383	normal	0.946587628	0.221453378	normal	0.973145794	-0.100319226	normal	0.822776504	0.062845378	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K13502|0|pps:100985816|STX4; syntaxin 4; K13502 syntaxin 4 (A)	SNARE interactions in vesicular transport (ko04130);; Vasopressin-regulated water reabsorption (ko04962)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Syntaxin;; SNARE domain	Syntaxin-4 GN=STX4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-4 [Oryctolagus cuniculus]
ENSG00000103502(CDIPT)	--	54.30374781	1663	47.76939042	1460	54.91757639	1695	47.99025496	1503	51.57881545	1607	61.53501	1893	0.972118088	-0.176603692	normal	0.979257359	0.116859598	normal	0.978039556	0.15097018	normal	0.905314848	0.034037036	normal	[I]	Lipid transport and metabolism	--	K00999|2.40084e-152|mcf:102125964|CDIPT; CDP-diacylglycerol--inositol 3-phosphatidyltransferase; K00999 CDP-diacylglycerol--inositol 3-phosphatidyltransferase [EC:2.7.8.11] (A)	Inositol phosphate metabolism (ko00562);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070)	[I]	Lipid transport and metabolism	--	CDP-diacylglycerol--inositol 3-phosphatidyltransferase GN=CDIPT OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X3 [Lipotes vexillifer]
ENSG00000103507(BCKDK)	--	31.92214233	1179	26.6578479	994	35.25006927	1276	36.6279151	1350	37.35805459	1360	28.76867893	1074	0.970627125	0.164363155	normal	0.64029539	0.430300589	normal	0.938949989	-0.256593865	normal	0.672393347	0.112267856	normal	[T]	Signal transduction mechanisms	--	K00905|0|ptr:741960|BCKDK; branched chain ketoacid dehydrogenase kinase; K00905 [3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase [EC:2.7.11.4] (A)	--	[T]	Signal transduction mechanisms	"Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	"[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial (Precursor) GN=BCKDK OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: 3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial [Ailuropoda melanoleuca] "
ENSG00000103510(KAT8)	--	17.083245	517	15.89575158	489	16.787983	521	14.03757488	446	15.25331177	458	14.51269845	441	0.930256876	-0.243173865	normal	0.964023886	-0.115544107	normal	0.928100897	-0.248012723	normal	0.402534623	-0.204221604	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K11308|0|cfr:102514307|KAT8; K(lysine) acetyltransferase 8; K11308 histone acetyltransferase MYST1 [EC:2.3.1.48] (A)	--	[B]	Chromatin structure and dynamics	MOZ/SAS family;; RNA binding activity-knot of a chromodomain	Histone acetyltransferase KAT8 GN=KAT8 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase KAT8 isoform X1 [Camelus ferus]
ENSG00000103512(NOMO1)	--	32.08460167	2853	33.10399674	2739	31.27430165	2679	24.44781998	2104	26.9459666	2299	21.92219467	1948	0.507940506	-0.469881345	normal	0.952145868	-0.273904044	normal	0.512630639	-0.467681388	normal	0.007817635	-0.40249082	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Carboxypeptidase regulatory-like domain;; Domain of unknown function (DUF4480);; Protein of unknown function (DUF2012);; Cna protein B-type domain;; Polysaccharide lyase family 4, domain II;; Protein of unknown function (DUF1416);; Y_Y_Y domain"	Nodal modulator 2 (Precursor) GN=NOMO2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nodal modulator 1 [Galeopterus variegatus]
ENSG00000103522(IL21R)	--	0.26619857	19	0.162956726	10	0.150782268	13	0.042464693	4	0.048706177	2	0.073946983	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05075|0|hsa:50615|IL21R, CD360, NILR; interleukin 21 receptor; K05075 interleukin 21 receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Inflammatory bowel disease (IBD) (ko05321)	--	--	--	Interleukin-21 receptor (Precursor) GN=IL21R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-21 receptor [Galeopterus variegatus]
ENSG00000103528(SYT17)	--	8.334825924	423	6.42045414	362	6.676890493	392	6.360119849	258	5.481042962	277	4.604237309	245	0.014279071	-0.740636405	normal	0.760758811	-0.405586968	normal	0.049690892	-0.6829992	normal	0.004064302	-0.614826475	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-17 GN=SYT17 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-17 isoform X1 [Galeopterus variegatus]
ENSG00000103534(TMC5)	--	3.122622189	308	2.977597863	296	4.512731969	401	4.101433957	410	4.50820351	410	4.698174634	471	0.795380234	0.380212687	normal	0.650114077	0.44665352	normal	0.93885871	0.223056423	normal	0.1421731	0.341043212	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 5 GN=TMC5 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane channel-like protein 5 [Odobenus rosmarus divergens]
ENSG00000103540(CCP110)	--	7.082609937	709	6.618567124	646	7.625992566	728	7.653605578	707	5.67228889	533	5.528610999	549	0.975020844	-0.034832087	normal	0.894930027	-0.298055682	normal	0.679187781	-0.414428972	normal	0.247873695	-0.241433938	normal	--	--	--	"K16453|0|hsa:9738|CCP110, CP110, Cep110; centriolar coiled coil protein 110kDa; K16453 centrosomal protein CEP110 (A)"	--	--	--	--	Centriolar coiled-coil protein of 110 kDa GN=CCP110 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: centriolar coiled-coil protein of 110 kDa isoform X1 [Galeopterus variegatus]
ENSG00000103544(C16orf62)	--	21.42080085	1283	23.28077419	1351	22.70631	1292	23.08568233	1362	21.3419325	1252	25.5504494	1499	0.981674904	0.055308983	normal	0.975597237	-0.131067217	normal	0.963167967	0.205878957	normal	0.866978052	0.046141748	normal	--	--	--	--	--	[S]	Function unknown	--	UPF0505 protein C16orf62 GN=C16orf62 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0505 protein C16orf62 homolog isoform X1 [Physeter catodon]
ENSG00000103549(RNF40)	--	25.0416791	2115	27.158988	2525	32.0146311	2630	27.30928109	2548	30.94662346	2672	31.2513853	2862	0.964222636	0.237717844	normal	0.988005218	0.060175026	normal	0.986470308	0.113606793	normal	0.525184117	0.132115852	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10696|0|hsa:9810|RNF40, BRE1B, RBP95, STARING; ring finger protein 40, E3 ubiquitin protein ligase (EC:6.3.2.-); K10696 E3 ubiquitin-protein ligase BRE1 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase BRE1B GN=RNF40 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase BRE1B isoform X2 [Ailuropoda melanoleuca] 
ENSG00000103550(KNOP1)	--	15.148405	1521	15.603128	1519	15.18285	1456	15.838569	1416	17.748071	1523	17.226059	1458	0.977291719	-0.13389093	normal	0.983713194	-0.017614972	normal	0.983763943	-0.006304534	normal	0.837475856	-0.053266457	normal	--	--	--	--	--	--	--	Small acidic protein family	Lysine-rich nucleolar protein 1 GN=KNOP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein C16orf88 homolog [Ceratotherium simum simum]
ENSG00000103569(AQP9)	--	0	0	0	0	0	0	0	0	0.018985	0	0.046685088	2	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K09877|0|hsa:366|AQP9, AQP-9, HsT17287, SSC1; aquaporin 9; K09877 aquaporin-9 (A)"	Bile secretion (ko04976)	[G]	Carbohydrate transport and metabolism	Major intrinsic protein	Aquaporin-9 GN=AQP9 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-9 [Canis lupus familiaris]
ENSG00000103591(AAGAB)	--	44.80269902	1931	40.45125099	1780	47.1655564	2099	44.95603629	2006	46.0997041	1963	41.457219	1751	0.986575685	0.024122347	normal	0.981519303	0.11965954	normal	0.945651674	-0.269601545	normal	0.871830381	-0.043852835	normal	--	--	--	--	--	[S]	Function unknown	Alpha and gamma adaptin binding protein p34	Alpha- and gamma-adaptin-binding protein p34 GN=AAGAB OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: alpha- and gamma-adaptin-binding protein p34 [Eptesicus fuscus]
ENSG00000103599(IQCH)	--	1.539799472	80	0.866513506	44	2.39982201	73	1.25646	53	1.43781304	58	1.31560538	48	0.816532136	-0.61033159	normal	0.957650731	0.366133124	normal	0.853253656	-0.597772418	normal	0.580229312	-0.330156371	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	--	IQ domain-containing protein H GN=IQCH OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: IQ domain-containing protein H [Ceratotherium simum simum]
ENSG00000103642(LACTB)	--	33.62896038	1284	25.46574827	981	35.15684	1240	44.84011765	1682	44.38468055	1631	43.352932	1564	0.837439995	0.358324663	normal	0.005373181	0.71114635	normal	0.885048103	0.326253904	normal	0.002476005	0.455394719	normal	[V]	Defense mechanisms	--	"K17382|0|pps:100968558|LACTB; lactamase, beta; K17382 serine beta-lactamase-like protein LACTB, mitochondrial (A)"	--	--	--	Beta-lactamase	"Serine beta-lactamase-like protein LACTB, mitochondrial (Precursor) GN=LACTB OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: serine beta-lactamase-like protein LACTB, mitochondrial isoform X1 [Oryctolagus cuniculus]"
ENSG00000103647(CORO2B)	--	0.535148589	39	0.122797281	9	0.561580918	41	2.10697827	154	1.665694609	121	0.842158528	62	2.28E-09	1.909864711	up	0	3.523025255	up	0.902176054	0.571110581	normal	0.012367683	1.898478139	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K13887|0|ocu:100342263|CORO2B; coronin-2B; K13887 coronin-2 (A)	--	[Z]	Cytoskeleton	"Domain of unknown function (DUF1900);; Domain of unknown function (DUF1899);; WD domain, G-beta repeat"	Coronin-2B GN=CORO2B OS=Homo sapiens (Human) PE=2 SV=4	Z	Cytoskeleton	PREDICTED: coronin-2B [Oryctolagus cuniculus]
ENSG00000103653(CSK)	--	33.87541454	1659	32.1239988	1600	33.16507643	1617	34.29816438	1654	33.68443777	1627	37.49789698	1814	0.984703688	-0.035154309	normal	0.984418604	0.002713245	normal	0.97653311	0.157424261	normal	0.877353366	0.042449789	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05728|0|pps:100975065|CSK; c-src tyrosine kinase; K05728 c-src tyrosine kinase [EC:2.7.10.2] (A)	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Tyrosine-protein kinase CSK GN=CSK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase CSK [Galeopterus variegatus] 
ENSG00000103657(HERC1)	--	7.265861503	1796	7.982195707	1995	7.813773698	1975	7.814494693	2150	7.77255693	2051	8.473140578	2171	0.963491348	0.228538174	normal	0.986551028	0.018498358	normal	0.982349935	0.128122028	normal	0.559081878	0.123047707	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	"K10594|0|hsa:8925|HERC1, p532, p619; HECT and RLD domain containing E3 ubiquitin protein ligase family member 1; K10594 E3 ubiquitin-protein ligase HERC1 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[S]	Function unknown	"Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat;; HECT-domain (ubiquitin-transferase);; WD domain, G-beta repeat;; SPRY domain"	Probable E3 ubiquitin-protein ligase HERC1 GN=HERC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: probable E3 ubiquitin-protein ligase HERC1 isoform X3 [Felis catus]
ENSG00000103671(TRIP4)	--	12.10613691	507	11.303891	469	12.72383233	491	10.75932192	454	12.31158421	512	10.91313863	458	0.950564416	-0.189518371	normal	0.96562097	0.104805823	normal	0.965715927	-0.108321347	normal	0.845091561	-0.06399254	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	--	--	[K]	Transcription	"ASCH domain;; Putative zinc finger motif, C2HC5-type"	Activating signal cointegrator 1 GN=TRIP4 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: activating signal cointegrator 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000103707(MTFMT)	--	9.05542894	385	10.13425994	427	9.774897212	410	10.69392174	455	8.312995292	353	9.187025669	391	0.943404194	0.209406462	normal	0.897701567	-0.294843989	normal	0.967136165	-0.076457925	normal	0.895946735	-0.04917784	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Biological Process: biosynthetic process (GO:0009058);; Molecular Function: hydroxymethyl-, formyl- and related transferase activity (GO:0016742);; "	"K00604|0|hsa:123263|MTFMT, COXPD15, FMT1; mitochondrial methionyl-tRNA formyltransferase (EC:2.1.2.9); K00604 methionyl-tRNA formyltransferase [EC:2.1.2.9] (A)"	One carbon pool by folate (ko00670);; Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"Formyl transferase;; Formyl transferase, C-terminal domain"	"Methionyl-tRNA formyltransferase, mitochondrial (Precursor) GN=MTFMT OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: LOW QUALITY PROTEIN: methionyl-tRNA formyltransferase, mitochondrial [Galeopterus variegatus]"
ENSG00000103710(RASL12)	--	0.128024815	6	0.0191757	1	0.041273757	1	0	0	0.036893765	0	0.105447456	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07854|0|hsa:51285|RASL12, RIS; RAS-like, family 12; K07854 Ras-like protein family member 12 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Ras-like protein family member 12 GN=RASL12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-like protein family member 12 [Ceratotherium simum simum]
ENSG00000103723(AP3B2)	--	0.137543946	9	0.094157143	6	0.281460833	18	0	0	0.104501041	1	0.112400981	8	--	--	--	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; 	"K12397|0|mcf:102121407|AP3B2; adaptor-related protein complex 3, beta 2 subunit; K12397 AP-3 complex subunit beta (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptin N terminal region;; Clathrin-adaptor complex-3 beta-1 subunit C-terminal;; HEAT repeats;; non-SMC mitotic condensation complex subunit 1;; HEAT repeat	AP-3 complex subunit beta-2 GN=AP3B2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-3 complex subunit beta-2 isoform 1 [Orcinus orca]
ENSG00000103740(ACSBG1)	--	4.9805599	577	5.13167169	593	5.36585107	618	5.4760866	635	4.5916839	530	4.743249	552	0.968382105	0.107081153	normal	0.953567856	-0.182972408	normal	0.957697867	-0.170787548	normal	0.786759512	-0.080046228	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K15013|0|pps:100987318|ACSBG1; acyl-CoA synthetase bubblegum family member 1; K15013 long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] (A)	Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	AMP-binding enzyme	Long-chain-fatty-acid--CoA ligase ACSBG1 GN=ACSBG1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: long-chain-fatty-acid--CoA ligase ACSBG1 [Equus caballus]
ENSG00000103742(IGDCC4)	--	3.12563535	388	2.801694272	356	2.884460223	364	10.5711567	1308	8.59842562	1062	13.252105	1657	0	1.718472532	up	1.78E-15	1.551405956	up	0	2.173627377	up	6.18E-08	1.841180814	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Immunoglobulin superfamily DCC subclass member 4 (Precursor) GN=IGDCC4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily DCC subclass member 4 [Galeopterus variegatus]
ENSG00000103769(RAB11A)	--	168.3881085	3197	154.9649545	2960	165.0158632	3079	188.5955859	3703	182.0842603	3682	162.1073304	3066	0.982888146	0.181062638	normal	0.950472318	0.293331294	normal	0.99035938	-0.01438853	normal	0.426227704	0.156616491	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07904|1.4745e-160|umr:103679069|RAB11A; RAB11A, member RAS oncogene family; K07904 Ras-related protein Rab-11A (A)"	Endocytosis (ko04144);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Vasopressin-regulated water reabsorption (ko04962);; Pancreatic secretion (ko04972)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; AAA domain;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-11A (Precursor) GN=RAB11A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	ras-related protein Rab-11A [Bos taurus] 
ENSG00000103811(CTSH)	--	18.51533678	486	16.88377216	472	13.24959641	359	17.64210445	476	28.43828778	743	24.0483937	574	0.969692246	-0.060633306	normal	0.055796833	0.631523211	normal	0.034485954	0.666535139	normal	0.239088943	0.424135553	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K01366|0|hsa:1512|CTSH, ACC-4, ACC-5, CPSB, minichain; cathepsin H (EC:3.4.22.16); K01366 cathepsin H [EC:3.4.22.16] (A)"	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin propeptide inhibitor domain (I29);; Peptidase C1-like family	Cathepsin H light chain (Precursor) GN=CTSH OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: pro-cathepsin H [Galeopterus variegatus]
ENSG00000103852(TTC23)	--	8.783021045	399	6.741831301	365	6.533152282	376	7.868442202	494	9.783575932	510	7.62997378	424	0.910488702	0.276332292	normal	0.578660291	0.459556647	normal	0.955408522	0.164417089	normal	0.181990383	0.303372037	normal	--	--	--	--	--	--	--	Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; SHNi-TPR;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 23 GN=TTC23 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 23 [Balaenoptera acutorostrata scammoni]
ENSG00000103855(CD276)	--	25.90073825	1589	25.554311	1653	27.46832704	1615	31.67659943	1935	29.47502467	1899	37.45011216	2278	0.951262632	0.253160076	normal	0.973455662	0.178574105	normal	0.405043593	0.487555899	normal	0.054587586	0.310843215	normal	--	--	--	"K06746|0|hsa:80381|CD276, 4Ig-B7-H3, B7-H3, B7H3, B7RP-2; CD276 molecule; K06746 immune costimulatory protein B7-H3 (A)"	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin C1-set domain	CD276 antigen (Precursor) GN=CD276 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CD276 antigen [Ailuropoda melanoleuca]
ENSG00000103876(FAH)	--	29.53145845	875	27.87468457	836	29.40637217	850	17.69550317	542	17.86353968	532	11.27916784	333	0.005676201	-0.720198934	normal	0.021562053	-0.671965702	normal	1.07E-11	-1.356233477	down	7.73E-08	-0.886533335	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: fumarylacetoacetase activity (GO:0004334);; Biological Process: metabolic process (GO:0008152);; Biological Process: aromatic amino acid family metabolic process (GO:0009072);; 	K01555|0|hsa:2184|FAH; fumarylacetoacetate hydrolase (fumarylacetoacetase) (EC:3.7.1.2); K01555 fumarylacetoacetase [EC:3.7.1.2] (A)	Tyrosine metabolism (ko00350)	[G]	Carbohydrate transport and metabolism	Fumarylacetoacetate (FAA) hydrolase family;; Fumarylacetoacetase N-terminal	Fumarylacetoacetase GN=FAH OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: fumarylacetoacetase [Ceratotherium simum simum]
ENSG00000103888(CEMIP)	--	1.165944549	29	0.239972334	27	0.2753485	26	0.12328428	15	0.3116579	24	0.468947043	22	0.915403396	-0.913506388	normal	0.984327313	-0.180614839	normal	0.985025235	-0.234458102	normal	0.580229312	-0.446928782	normal	--	--	--	--	--	--	--	G8 domain;; Mucin-2 protein WxxW repeating region;; Right handed beta helix region	Cell migration-inducing and hyaluronan-binding protein (Precursor) GN=CEMIP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cell migration-inducing and hyaluronan-binding protein isoform X1 [Galeopterus variegatus]
ENSG00000103932(RPAP1)	--	5.036348235	479	5.654731375	531	5.767033397	556	4.996805603	471	4.997616019	440	5.987964554	555	0.969872849	-0.054953096	normal	0.899296232	-0.291720663	normal	0.972877385	-0.010858991	normal	0.678807371	-0.115778917	normal	--	--	--	--	--	[S]	Function unknown	"RPAP1-like, C-terminal;; RPAP1-like, N-terminal"	RNA polymerase II-associated protein 1 GN=RPAP1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: RNA polymerase II-associated protein 1 [Orcinus orca]
ENSG00000103942(HOMER2)	--	5.643095173	482	4.684666715	430	5.203269784	452	5.434837651	441	5.562785276	455	3.900053568	364	0.957586976	-0.158558107	normal	0.968199779	0.059898527	normal	0.874581261	-0.319482198	normal	0.634586104	-0.136094273	normal	--	--	--	K15010|0|mcf:102117763|HOMER2; homer homolog 2 (Drosophila); K15010 homer (A)	FoxO signaling pathway (ko04068);; Glutamatergic synapse (ko04724)	--	--	WH1 domain	Homer protein homolog 2 GN=HOMER2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: homer protein homolog 2 isoform X1 [Orycteropus afer afer]
ENSG00000103966(EHD4)	--	6.150039	788	6.0411305	780	6.1526215	791	6.333528277	811	6.2178522	791	4.2819029	550	0.976889915	0.010653546	normal	0.976206075	-0.001220637	normal	0.245541741	-0.531312437	normal	0.568635952	-0.154699293	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; 	"K12477|0|hsa:30844|EHD4, PAST4; EH-domain containing 4; K12477 EH domain-containing protein 4 (A)"	Endocytosis (ko04144)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Dynamin family;; Cytoskeletal-regulatory complex EF hand;; 50S ribosome-binding GTPase	EH domain-containing protein 4 GN=EHD4 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: EH domain-containing protein 4 [Canis lupus familiaris]
ENSG00000103978(TMEM87A)	--	10.188723	449	14.3159465	627	10.702189	465	13.286828	564	11.28133092	510	14.43749473	635	0.893871977	0.297238353	normal	0.873993888	-0.318541159	normal	0.606752979	0.44000513	normal	0.711972148	0.128076539	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Lung seven transmembrane receptor	Transmembrane protein 87A (Precursor) GN=TMEM87A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transmembrane protein 87A isoform X4 [Galeopterus variegatus]
ENSG00000103994(ZNF106)	--	6.796401101	1250	6.569382375	1222	8.165242821	1386	8.046815412	1461	7.675306445	1397	6.865842309	1288	0.965611895	0.193975123	normal	0.969681447	0.171462607	normal	0.978148417	-0.113957089	normal	0.728258727	0.082521292	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Zinc finger protein 106 GN=ZNF106 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 106 [Ceratotherium simum simum]
ENSG00000103995(CEP152)	--	3.36292449	509	3.6166051	617	4.293082032	676	3.053463347	467	2.600938567	394	3.236939	521	0.958905238	-0.154587989	normal	0.03459125	-0.666439138	normal	0.764344551	-0.383052336	normal	0.066610275	-0.403476889	normal	--	--	--	"K16728|0|hsa:22995|CEP152, MCPH4, MCPH9, SCKL5; centrosomal protein 152kDa; K16728 centrosomal protein CEP152 (A)"	--	--	--	--	Centrosomal protein of 152 kDa GN=CEP152 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: centrosomal protein of 152 kDa isoformX2 [Canis lupus familiaris]
ENSG00000104043(ATP8B4)	--	0.48126297	37	0.45402002	35	0.82422811	43	0.91340453	48	0.69402951	44	0.6104373	50	0.970156862	0.332527122	normal	0.972677776	0.297247186	normal	0.975586038	0.202684077	normal	0.697475938	0.283486819	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:79895|ATP8B4, ATPIM; ATPase, class I, type 8B, member 4 (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase IM GN=ATP8B4 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IM [Orcinus orca]
ENSG00000104044(OCA2)	--	0.351141577	18	0.393650815	7	0.257458696	12	0.037381403	2	0.038019063	1	0.066118219	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[P]	Inorganic ion transport and metabolism	Citrate transporter;; Sodium:sulfate symporter transmembrane region;; Arsenical pump membrane protein	P protein GN=OCA2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: P protein [Ceratotherium simum simum]
ENSG00000104047(DTWD1)	--	12.25018879	336	11.63186812	330	14.95799298	339	10.75757608	309	10.50963174	313	14.73148788	418	0.95679567	-0.150966494	normal	0.962922604	-0.097272137	normal	0.899956491	0.292748122	normal	0.951909417	0.029127224	normal	--	--	--	--	--	[S]	Function unknown	DTW domain	DTW domain-containing protein 1 GN=DTWD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DTW domain-containing protein 1 [Ailuropoda melanoleuca] 
ENSG00000104055(TGM5)	--	0	0	0	0	0.049138828	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein-glutamine gamma-glutamyltransferase activity (GO:0003810);; Biological Process: peptide cross-linking (GO:0018149);; 	K05622|0|ggo:101149000|TGM5; protein-glutamine gamma-glutamyltransferase 5 isoform 1; K05622 transglutaminase 5 [EC:2.3.2.13] (A)	--	--	--	"Transglutaminase family, C-terminal ig like domain;; Transglutaminase family;; Transglutaminase-like superfamily"	Protein-glutamine gamma-glutamyltransferase 5 GN=TGM5 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-glutamine gamma-glutamyltransferase 5 isoform X1 [Equus przewalskii]
ENSG00000104059(FAM189A1)	--	0.420381686	38	0.240607358	22	0.3552251	31	0.214589648	18	0.461651642	39	0.292352741	26	0.735854063	-1.046035066	normal	0.903596212	0.764607093	normal	0.98225297	-0.248779691	normal	0.883493494	-0.152581209	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	CD20-like family	Protein FAM189A1 GN=FAM189A1 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM189A1 [Equus caballus]
ENSG00000104064(GABPB1)	--	17.71528	670	14.402831	620	16.212878	691	13.58751712	626	17.18536755	758	13.998388	606	0.966546813	-0.128525694	normal	0.920474845	0.267911231	normal	0.952066139	-0.197198149	normal	0.971576238	-0.014490035	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K09454|0|umr:103676732|GABPB1; GA binding protein transcription factor, beta subunit 1; K09454 GA-binding protein transcription factor, beta (A)"	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	GA-binding protein subunit beta-1 GN=GABPB1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: GA-binding protein subunit beta-1 isoform X8 [Tupaia chinensis]
ENSG00000104067(TJP1)	--	41.9638069	4552	45.14134821	4859	37.8198926	4517	44.93120578	4982	44.12044908	4919	43.1738404	4660	0.991630045	0.099360138	normal	0.993078443	-0.003719785	normal	0.992748914	0.036661514	normal	0.877480075	0.042657551	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05701|0|hsa:7082|TJP1, ZO-1; tight junction protein 1; K05701 tight junction protein 1 (A)"	Adherens junction (ko04520);; Tight junction (ko04530);; Gap junction (ko04540);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Salmonella infection (ko05132)	[T]	Signal transduction mechanisms	PDZ domain (Also known as DHR or GLGF);; ZU5 domain;; PDZ domain;; Guanylate kinase;; Variant SH3 domain	Tight junction protein ZO-1 GN=TJP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	tight junction protein ZO-1 [Canis lupus familiaris] 
ENSG00000104081(BMF)	--	0.959194814	56	2.452771633	126	0.362129906	36	0.949104023	45	1.65717225	142	3.032040592	126	0.96410548	-0.336026533	normal	0.960033481	0.149351377	normal	4.62E-07	1.757125967	up	0.691086411	0.501733374	normal	--	--	Biological Process: apoptotic process (GO:0006915);; 	K17460|9.42635e-114|hsa:90427|BMF; Bcl2 modifying factor; K17460 Bcl-2-modifying factor (A)	MicroRNAs in cancer (ko05206)	--	--	"Bcl-2-modifying factor, apoptosis"	Bcl-2-modifying factor GN=BMF OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: bcl-2-modifying factor isoform X2 [Camelus ferus] 
ENSG00000104093(DMXL2)	--	14.82641201	2660	21.241318	2771	14.326929	2520	12.57468892	2166	11.93584979	2108	16.93389944	2464	0.909131388	-0.327015503	normal	0.74373889	-0.415697397	normal	0.988415422	-0.040688226	normal	0.124623579	-0.25978176	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"RAVE protein 1 C terminal;; WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	DmX-like protein 2 GN=DMXL2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: Dmx-like 2 isoformX1 [Canis lupus familiaris]
ENSG00000104112(SCG3)	--	0.065440919	4	0.045196986	2	0.098208237	5	0	0	0.054745438	2	0.030793731	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Secretogranin-3;; Protein of unknown function (DUF2680)	Secretogranin-3 (Precursor) GN=SCG3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: secretogranin-3 isoform X1 [Galeopterus variegatus]
ENSG00000104129(DNAJC17)	--	6.888591	112	10.512533	133	7.495155	173	7.008045	135	9.472481	166	8.548529	133	0.950487398	0.235680378	normal	0.925321784	0.295319558	normal	0.873397228	-0.383799559	normal	0.96328771	0.033692503	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: nucleic acid binding (GO:0003676);; 	"K09537|1.11152e-154|hsa:55192|DNAJC17; DnaJ (Hsp40) homolog, subfamily C, member 17; K09537 DnaJ homolog subfamily C member 17 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"DnaJ domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	DnaJ homolog subfamily C member 17 GN=DNAJC17 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 17 [Loxodonta africana]
ENSG00000104131(EIF3J)	--	31.488027	1262	31.547069	1279	30.30871075	1216	37.656701	1521	38.237818	1547	28.06249	1115	0.951828241	0.238211517	normal	0.946176358	0.25275829	normal	0.974180321	-0.133217881	normal	0.612216551	0.132883395	normal	--	--	Molecular Function: translation initiation factor activity (GO:0003743);; Cellular Component: cytoplasm (GO:0005737);; Cellular Component: eukaryotic translation initiation factor 3 complex (GO:0005852);; 	"K03245|4.80444e-69|pps:100985968|EIF3J; eukaryotic translation initiation factor 3, subunit J; K03245 translation initiation factor 3 subunit J (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Translation initiation factor eIF3 subunit	Eukaryotic translation initiation factor 3 subunit J {ECO:0000255|HAMAP-Rule:MF_03009} OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	hypothetical protein PANDA_000999 [Ailuropoda melanoleuca]
ENSG00000104133(SPG11)	--	5.389653198	775	5.913103947	857	6.216147284	794	5.899663783	812	6.546445146	823	6.504602924	963	0.976309502	0.036380691	normal	0.974399534	-0.079685826	normal	0.923748188	0.269638342	normal	0.76875221	0.078062966	normal	--	--	--	--	--	[S]	Function unknown	Spatacsin C-terminus	Spatacsin GN=SPG11 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: spatacsin isoform 1 [Ceratotherium simum simum]
ENSG00000104140(RHOV)	--	9.84306	295	6.69746	208	7.44829	232	5.19238	159	5.58885	166	7.22059	218	0.001503705	-0.915913281	normal	0.886470802	-0.344020441	normal	0.963154536	-0.0974328	normal	0.134357373	-0.457110697	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07866|4.07465e-153|ptr:467658|RHOV; ras homolog family member V; K07866 Ras homolog gene family, member V (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoV OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoV [Camelus dromedarius]
ENSG00000104142(VPS18)	--	10.60369488	828	11.5013142	921	11.1984133	851	14.73583149	1151	17.796305	1369	21.28686951	1641	0.56759027	0.443651924	normal	0.178260528	0.549678055	normal	4.77E-06	0.937831358	normal	0.004738061	0.658232423	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Pep3/Vps18/deep orange family;; Region in Clathrin and VPS	Vacuolar protein sorting-associated protein 18 homolog GN=VPS18 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 18 homolog [Ceratotherium simum simum]
ENSG00000104147(OIP5)	--	11.600665	182	11.72600061	199	11.63870053	195	10.844972	178	9.180470461	153	9.218160608	154	0.965824866	-0.062361114	normal	0.843128421	-0.397209976	normal	0.89160147	-0.345810168	normal	0.460170823	-0.269738982	normal	--	--	--	"K11565|2.81707e-154|hsa:11339|OIP5, 5730547N13Rik, CT86, LINT-25, MIS18B, MIS18beta, hMIS18beta; Opa interacting protein 5; K11565 opa-interacting protein 5 (A)"	--	--	--	"Yippee zinc-binding/DNA-binding /Mis18, centromere assembly"	Protein Mis18-beta GN=OIP5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein Mis18-beta [Balaenoptera acutorostrata scammoni]
ENSG00000104154(SLC30A4)	--	2.200609933	183	2.396222	175	3.072232574	192	1.61813981	170	1.94227155	171	1.662256746	175	0.960296652	-0.135956454	normal	0.965016507	-0.054310351	normal	0.959433645	-0.140880084	normal	0.804262495	-0.113024577	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14691|0|hsa:7782|SLC30A4, ZNT4; solute carrier family 30 (zinc transporter), member 4; K14691 solute carrier family 30 (zinc transporter), member 4 (A)"	--	[P]	Inorganic ion transport and metabolism	Cation efflux family	Zinc transporter 4 GN=SLC30A4 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter 4 [Camelus ferus] 
ENSG00000104164(BLOC1S6)	--	69.63165465	2813	64.47055936	2691	66.47133753	2656	73.7376985	3057	69.59865174	2800	78.54889381	3197	0.988340848	0.089128032	normal	0.98898954	0.035838134	normal	0.962016956	0.25903754	normal	0.537343006	0.12883565	normal	--	--	--	--	--	--	--	Snapin/Pallidin	Biogenesis of lysosome-related organelles complex 1 subunit 6 GN=BLOC1S6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: biogenesis of lysosome-related organelles complex 1 subunit 6 isoform X2 [Balaenoptera acutorostrata scammoni] 
ENSG00000104177(MYEF2)	--	23.28315592	1419	23.88741977	1613	23.77375516	1539	19.14663756	1176	16.31776652	1020	20.96087909	1263	0.908891935	-0.301459601	normal	0.010931321	-0.681792524	normal	0.919311619	-0.293111548	normal	0.005712381	-0.42319465	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif;; Limkain b1"	Myelin expression factor 2 GN=MYEF2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: myelin expression factor 2 isoform 1 [Dasypus novemcinctus]
ENSG00000104205(SGK3)	--	4.126135889	172	3.187247901	172	2.79459797	133	4.126240583	211	3.8348505	192	4.931483729	189	0.931596236	0.261887187	normal	0.958715978	0.136137879	normal	0.712430959	0.493934156	normal	0.410591586	0.289623574	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K13304|0|pps:100987089|SGK3; serum/glucocorticoid regulated kinase family, member 3; K13304 serum/glucocorticoid-regulated kinase 3 [EC:2.7.11.1] (A)"	FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151)	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PX domain;; Protein kinase C terminal domain	Serine/threonine-protein kinase Sgk3 GN=SGK3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Sgk3 isoform X1 [Ochotona princeps] 
ENSG00000104213(PDGFRL)	--	10.59028	392	8.53331646	315	8.21977142	305	7.32530965	273	9.6745065	356	9.49542935	353	0.308367784	-0.550185315	normal	0.955421307	0.154401264	normal	0.945418676	0.201637419	normal	0.867131421	-0.063996386	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Platelet-derived growth factor receptor-like protein (Precursor) GN=PDGFRL OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: platelet-derived growth factor receptor-like protein [Pteropus alecto]
ENSG00000104218(CSPP1)	--	5.00671	504	5.52348	551	6.036035	597	5.65128	570	4.704864646	471	5.387239	542	0.961439464	0.146286415	normal	0.928690642	-0.247017649	normal	0.962107272	-0.147337646	normal	0.782273299	-0.082771362	normal	--	--	--	K16771|0|pps:100983291|CSPP1; centrosome and spindle pole associated protein 1; K16771 centrosome and spindle pole-associated protein 1 (A)	--	--	--	Coiled-coil domain-containing protein 66	Centrosome and spindle pole-associated protein 1 GN=CSPP1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: centrosome and spindle pole-associated protein 1 isoform X3 [Camelus bactrianus]
ENSG00000104219(ZDHHC2)	--	14.43601866	1291	14.75103509	1309	14.41332183	1270	13.25627131	1201	12.3929579	1044	13.9904255	1264	0.974849904	-0.134918581	normal	0.851264024	-0.347319562	normal	0.982204408	-0.015105446	normal	0.418417897	-0.162418369	normal	[R]	General function prediction only	--	"K18932|0|ptr:464005|ZDHHC2; zinc finger, DHHC-type containing 2; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC2 GN=ZDHHC2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC2 [Odobenus rosmarus divergens]
ENSG00000104221(BRF2)	--	5.367960001	246	6.705973	288	4.81834	224	6.29176277	284	6.336147262	278	5.523893	244	0.952084026	0.175380296	normal	0.96431369	-0.072025509	normal	0.961542681	0.114351082	normal	0.874611439	0.066628962	normal	[K]	Transcription	--	"K15197|0|ptr:746619|BRF2, ZFP36L2; BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit; K15197 transcription factor IIIB 50 kDa subunit (A)"	--	[K]	Transcription	TFIIB zinc-binding;; Transcription factor TFIIB repeat	Transcription factor IIIB 50 kDa subunit GN=BRF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor IIIB 50 kDa subunit [Camelus ferus] 
ENSG00000104228(TRIM35)	--	8.2905443	609	7.341122137	565	8.399457629	633	10.30330968	771	9.582475	691	9.395917427	700	0.884609838	0.308762752	normal	0.91871487	0.268357856	normal	0.965856075	0.136547647	normal	0.252103392	0.23740566	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K12012|0|nle:100599168|TRIM35; tripartite motif containing 35; K12012 tripartite motif-containing protein 35 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger"	Tripartite motif-containing protein 35 GN=TRIM35 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 35 [Oryctolagus cuniculus]
ENSG00000104231(ZFAND1)	--	17.10265863	412	14.58943716	353	14.15989657	353	17.244189	384	16.1584531	323	13.14296303	320	0.960995781	-0.131860778	normal	0.956434878	-0.148893458	normal	0.957378973	-0.149216014	normal	0.638639343	-0.144390536	normal	[R]	General function prediction only	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	AN1-like Zinc finger	AN1-type zinc finger protein 1 GN=ZFAND1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: AN1-type zinc finger protein 1 [Oryctolagus cuniculus]
ENSG00000104237(RP1)	--	0.00737244	1	0.013279408	1	0.00740149	0	0.07523957	9	0.066772096	7	0.128677843	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[S]	Function unknown	Doublecortin	Oxygen-regulated protein 1 GN=RP1 OS=Homo sapiens (Human) PE=1 SV=1	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: LOW QUALITY PROTEIN: oxygen-regulated protein 1 [Galeopterus variegatus]
ENSG00000104267(CA2)	--	1.52672	41	0.698806	19	1.16867	31	2.64198	72	2.30555	62	1.9433	53	0.691151506	0.759806205	normal	0.004557419	1.610165776	up	0.844047676	0.737612789	normal	0.036231504	1.01719083	normal	[P]	Inorganic ion transport and metabolism	--	"K18245|0|hsa:760|CA2, CA-II, CAC, CAII, Car2, HEL-76; carbonic anhydrase II (EC:4.2.1.1); K18245 carbonic anhydrase 2 [EC:4.2.1.1] (A)"	Nitrogen metabolism (ko00910);; Proximal tubule bicarbonate reclamation (ko04964);; Collecting duct acid secretion (ko04966);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase 2 GN=CA2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carbonic anhydrase 2 [Leptonychotes weddellii]
ENSG00000104290(FZD3)	--	4.2260023	387	3.444572745	381	3.64895235	400	3.989503	564	4.365678	497	3.229491	431	0.365702148	0.510840608	normal	0.820357501	0.360771267	normal	0.965493356	0.099035648	normal	0.130490433	0.331281614	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	K02329|0|ptr:472726|FZD3; frizzled class receptor 3; K02329 frizzled 3 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-3 (Precursor) GN=FZD3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: frizzled-3 [Myotis lucifugus] 
ENSG00000104299(INTS9)	--	8.769878027	399	8.495663137	386	10.21541395	437	9.37086056	427	9.950444428	460	8.468196648	397	0.967925488	0.066766518	normal	0.934888463	0.230777356	normal	0.959183344	-0.146254473	normal	0.891389285	0.050260207	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K13146|0|pon:100458919|INTS9; integrator complex subunit 9; K13146 integrator complex subunit 9 (A)	--	[A]	RNA processing and modification	Beta-Casp domain	Integrator complex subunit 9 GN=INTS9 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: integrator complex subunit 9 isoform X2 [Physeter catodon]
ENSG00000104312(RIPK2)	--	13.07368	599	11.17089	527	12.50743	564	16.66166	779	14.26675	679	16.89902	778	0.832449386	0.347451698	normal	0.842310488	0.343312101	normal	0.537677566	0.454741079	normal	0.036723356	0.382671833	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K08846|0|hsa:8767|RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP2; receptor-interacting serine-threonine kinase 2 (EC:2.7.11.1 2.7.10.2); K08846 receptor-interacting serine/threonine-protein kinase 2 [EC:2.7.11.1] (A)"	NOD-like receptor signaling pathway (ko04621);; Neurotrophin signaling pathway (ko04722);; Shigellosis (ko05131);; Tuberculosis (ko05152)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Caspase recruitment domain	Receptor-interacting serine/threonine-protein kinase 2 GN=UNQ277/PRO314/PRO34092 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-interacting serine/threonine-protein kinase 2 [Galeopterus variegatus]
ENSG00000104313(EYA1)	--	0	0	0	0	0	0	0	0	0	0	0.015530502	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15616|0|hsa:2138|EYA1, BOP, BOR, BOS1, OFC1; EYA transcriptional coactivator and phosphatase 1 (EC:3.1.3.16 3.1.3.48); K15616 eyes absent homolog 1 [EC:3.1.3.48] (A)"	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	--	Eyes absent homolog 1 GN=EYA1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: eyes absent homolog 1-like isoform X3 [Tupaia chinensis] 
ENSG00000104320(NBN)	--	14.71660884	1209	18.31960177	1264	13.81034419	1096	18.16687712	1492	20.97792043	1621	18.47288985	1451	0.933162852	0.272289082	normal	0.87552917	0.337104118	normal	0.741305028	0.396031863	normal	0.039428123	0.333339843	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10867|0|hsa:4683|NBN, AT-V1, AT-V2, ATV, NBS, NBS1, P95; nibrin; K10867 nijmegen breakage syndrome protein 1 (A)"	Homologous recombination (ko03440)	--	--	DNA damage repair protein Nbs1;; FHA domain;; BRCA1 C Terminus (BRCT) domain	Nibrin GN=NBN OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: nibrin isoform X1 [Equus przewalskii]
ENSG00000104321(TRPA1)	--	0.818270391	62	0.765561	52	1.019011782	69	1.537567	114	1.218672381	86	0.96536825	82	0.219733815	0.832436942	normal	0.690000206	0.688676721	normal	0.962814769	0.235986341	normal	0.168578689	0.601949321	normal	[R]	General function prediction only	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04984|0|hsa:8989|TRPA1, ANKTM1, FEPS; transient receptor potential cation channel, subfamily A, member 1; K04984 transient receptor potential cation channel subfamily A member 1 (A)"	Inflammatory mediator regulation of TRP channels (ko04750)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ion transport protein	Transient receptor potential cation channel subfamily A member 1 GN=TRPA1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily A member 1 [Galeopterus variegatus]
ENSG00000104324(CPQ)	--	6.572674141	269	6.4601486	257	4.712982163	201	2.412530102	101	3.3213551	116	3.092400933	109	2.67E-08	-1.4301996	down	2.68E-05	-1.158647243	down	0.014785922	-0.882006406	normal	4.61E-06	-1.17844007	down	[R]	General function prediction only	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[OPR]	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism;; General function prediction only"	Peptidase family M28;; Peptidase family M20/M25/M40	Carboxypeptidase Q (Precursor) GN=CPQ OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: carboxypeptidase Q [Vicugna pacos]
ENSG00000104325(DECR1)	--	38.90838087	629	35.65873756	578	28.731686	474	39.55019149	656	42.27489593	682	40.18825024	665	0.974038696	0.029732419	normal	0.944578703	0.216753123	normal	0.460235664	0.478879999	normal	0.280338684	0.231320897	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K13236|0|pps:100985245|DECR1; 2,4-dienoyl CoA reductase 1, mitochondrial; K13236 2,4-dienoyl-CoA reductase, mitochondrial [EC:1.3.1.34] (A)"	--	[R]	General function prediction only	Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase;; KR domain	"2,4-dienoyl-CoA reductase, mitochondrial (Precursor) GN=DECR1 OS=Homo sapiens (Human) PE=1 SV=1"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: 2,4-dienoyl-CoA reductase, mitochondrial [Tupaia chinensis]"
ENSG00000104327(CALB1)	--	0	0	0.032979331	1	0.047982206	0	0	0	0.031962479	0	0.130962721	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K14757|0|ptr:464279|CALB1; calbindin 1, 28kDa; K14757 calbindin D28 (A)"	Endocrine and other factor-regulated calcium reabsorption (ko04961)	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain;; EF-hand domain pair;; EF hand;; EF-hand domain pair	Calbindin GN=CALB1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calbindin [Condylura cristata]
ENSG00000104331(IMPAD1)	--	39.47773	3974	40.2955	4070	39.03914	3865	39.50257	4026	36.7008	3687	33.39012	3362	0.99214965	-0.012072327	normal	0.985889872	-0.163943901	normal	0.979307372	-0.209352226	normal	0.553533874	-0.126556628	normal	[P]	Inorganic ion transport and metabolism	Biological Process: phosphatidylinositol phosphorylation (GO:0046854);; 	K15759|0|ptr:464188|IMPAD1; inositol monophosphatase domain containing 1; K15759 inositol monophosphatase 3 [EC:3.1.3.25 3.1.3.7] (A)	Inositol phosphate metabolism (ko00562);; Sulfur metabolism (ko00920);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	Inositol monophosphatase family	Inositol monophosphatase 3 GN=IMPAD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inositol monophosphatase 3 [Ceratotherium simum simum]
ENSG00000104332(SFRP1)	--	39.86291321	3204	32.71951608	2653	37.30021347	3004	26.806526	2153	22.52251413	1803	17.70151917	1424	0.055951836	-0.604002182	normal	0.110242742	-0.578249328	normal	8.94E-09	-1.084415401	down	4.37E-05	-0.742201613	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K02166|1.31691e-173|hsa:6422|SFRP1, FRP, FRP-1, FRP1, FrzA, SARP2; secreted frizzled-related protein 1; K02166 secreted frizzled-related protein 1 (A)"	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Fz domain;; UNC-6/NTR/C345C module	Secreted frizzled-related protein 1 (Precursor) GN=SFRP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: secreted frizzled-related protein 1 [Erinaceus europaeus]
ENSG00000104341(LAPTM4B)	--	149.390828	4557	152.2002	4826	138.2035	4333	132.221666	4197	131.8838401	4218	146.586362	4618	0.988442459	-0.149505624	normal	0.981428568	-0.215623039	normal	0.991691186	0.083582233	normal	0.682276928	-0.094753469	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K12387|5.86368e-152|hsa:55353|LAPTM4B, LAPTM4beta, LC27; lysosomal protein transmembrane 4 beta; K12387 lysosomal-associated transmembrane protein (A)"	Lysosome (ko04142)	--	--	Golgi 4-transmembrane spanning transporter	Lysosomal-associated transmembrane protein 4B GN=LAPTM4B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lysosomal-associated transmembrane protein 4B [Orcinus orca]
ENSG00000104343(UBE2W)	--	14.2830102	602	15.4140987	636	14.64047841	536	15.11957071	619	14.46735917	594	15.82225955	640	0.973809016	0.009320201	normal	0.966524194	-0.119695811	normal	0.930511192	0.246909158	normal	0.899311644	0.041484346	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10688|1.07472e-127|ptr:464234|UBE2W; ubiquitin-conjugating enzyme E2W (putative); K10688 ubiquitin-conjugating enzyme E2 W [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 W GN=UBE2W OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 W-like [Physeter catodon]
ENSG00000104356(POP1)	--	4.620702631	390	3.336666506	292	3.8139712	350	5.633951951	473	5.88775634	414	3.227308832	235	0.928049651	0.246650411	normal	0.547371997	0.480137868	normal	0.255793525	-0.57990708	normal	0.884192625	0.097685967	normal	--	--	Biological Process: tRNA 5'-leader removal (GO:0001682);; Molecular Function: ribonuclease P activity (GO:0004526);; Biological Process: RNA processing (GO:0006396);; 	"K01164|0|hsa:10940|POP1; processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) (EC:3.1.26.5); K01164 ribonuclease P/MRP protein subunit POP1 [EC:3.1.26.5] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[A]	RNA processing and modification	Ribonucleases P/MRP protein subunit POP1;; POPLD (NUC188) domain	Ribonucleases P/MRP protein subunit POP1 GN=POP1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribonucleases P/MRP protein subunit POP1 [Galeopterus variegatus]
ENSG00000104361(NIPAL2)	--	1.4769695	109	1.597158722	117	1.65744021	119	2.432628583	180	2.679210868	196	2.49221003	187	0.259042022	0.685249412	normal	0.162367211	0.715697926	normal	0.354616989	0.637272147	normal	0.023647103	0.685579879	normal	--	--	Molecular Function: magnesium ion transmembrane transporter activity (GO:0015095);; Biological Process: magnesium ion transport (GO:0015693);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Magnesium transporter NIPA	NIPA-like protein 2 GN=NIPAL2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: NIPA-like protein 2 [Equus przewalskii]
ENSG00000104365(IKBKB)	--	15.19029348	947	12.6656288	1000	14.60184034	955	12.34682124	906	13.86333381	883	16.56828986	1009	0.975001789	-0.094528818	normal	0.956894258	-0.200618096	normal	0.977462283	0.070952774	normal	0.776500535	-0.073584196	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Molecular Function: IkappaB kinase activity (GO:0008384);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K07209|0|ptr:472749|IKBKB; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; K07209 inhibitor of nuclear factor kappa-B kinase subunit beta [EC:2.7.11.10] (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; FoxO signaling pathway (ko04068);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; I-kappa-kinase-beta NEMO binding domain;; Lipopolysaccharide kinase (Kdo/WaaP) family	Inhibitor of nuclear factor kappa-B kinase subunit beta GN=IKBKB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1 [Orycteropus afer afer]
ENSG00000104368(PLAT)	--	3.640447044	153	2.859284675	105	1.906970433	101	4.539577487	248	5.192296582	271	3.376381542	184	0.177411306	0.660719228	normal	4.26E-07	1.334086395	up	0.035713759	0.847521407	normal	0.001760596	0.947303889	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	"K01343|0|hsa:5327|PLAT, T-PA, TPA; plasminogen activator, tissue (EC:3.4.21.68); K01343 tissue plasminogen activator [EC:3.4.21.68] (A)"	Complement and coagulation cascades (ko04610);; Transcriptional misregulation in cancer (ko05202)	--	--	Trypsin;; Kringle domain;; Fibronectin type I domain;; EGF-like domain	Tissue-type plasminogen activator chain B (Precursor) GN=PLAT OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tissue-type plasminogen activator [Ceratotherium simum simum]
ENSG00000104369(JPH1)	--	0.0912017	7	0	0	0	0	0	0	0.0125508	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	MORN repeat	Junctophilin-1 GN=JPH1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: junctophilin-1 [Odobenus rosmarus divergens]
ENSG00000104375(STK3)	--	11.00469302	466	10.53126101	466	11.39388317	472	10.05056636	479	11.58744562	472	10.04240998	430	0.97114276	0.008834708	normal	0.970392012	-0.002960108	normal	0.960525549	-0.142263895	normal	0.899311644	-0.045297597	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04412|0|hsa:6788|STK3, KRS1, MST2; serine/threonine kinase 3 (EC:2.7.11.1); K04412 serine/threonine kinase 3 (A)"	MAPK signaling pathway (ko04010);; Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; C terminal SARAH domain of Mst1	Serine/threonine-protein kinase 3 20kDa subunit GN=STK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	Serine/threonine-protein kinase 3 [Pteropus alecto]
ENSG00000104381(GDAP1)	--	9.670231158	584	9.665845911	588	10.30517497	607	9.74693746	594	8.33408259	501	8.917899217	538	0.973435832	-0.006321212	normal	0.926845535	-0.251729844	normal	0.954720628	-0.181900095	normal	0.56968376	-0.145038154	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Ganglioside-induced differentiation-associated protein 1 GN=GDAP1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: ganglioside-induced differentiation-associated protein 1 isoform X1 [Equus caballus]
ENSG00000104388(RAB2A)	--	82.5487417	2429	76.44677031	2414	78.57929111	2279	87.43127667	2556	96.13456302	2526	85.23037733	2363	0.988376852	0.042666773	normal	0.987959481	0.043975473	normal	0.987739355	0.043898654	normal	0.874611439	0.042474442	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07877|1.40521e-145|ssc:100151822|RAB2A; RAB2A, member RAS oncogene family; K07877 Ras-related protein Rab-2A (A)"	AMPK signaling pathway (ko04152)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-2A GN=RAB2A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-2A [Sus scrofa] 
ENSG00000104408(EIF3E)	--	253.3587321	5747	235.1772892	5280	239.3699205	5294	225.0219193	5243	230.415734	5259	217.6728458	5001	0.989414151	-0.163203063	normal	0.993379226	-0.027168194	normal	0.992368969	-0.090406456	normal	0.685025699	-0.095550692	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03250|0|mcf:101926076|EIF3E, EIF3S6, INT6, QtsA-18056; Eukaryotic translation initiation factor 3 subunit E; K03250 translation initiation factor 3 subunit E (A)"	RNA transport (ko03013);; Hepatitis C (ko05160)	[J]	"Translation, ribosomal structure and biogenesis"	eIF3 subunit 6 N terminal domain;; PCI domain	Eukaryotic translation initiation factor 3 subunit E {ECO:0000255|HAMAP-Rule:MF_03004} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit E [Trichechus manatus latirostris]
ENSG00000104412(EMC2)	--	20.03557931	453	21.5408032	488	24.31490541	544	18.81401987	431	16.16990568	366	15.47700536	352	0.965575986	-0.102299666	normal	0.657374071	-0.434901963	normal	0.066629098	-0.634113544	normal	0.062577808	-0.391681332	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	ER membrane protein complex subunit 2 GN=EMC2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ER membrane protein complex subunit 2 [Orcinus orca] 
ENSG00000104413(ESRP1)	--	0.020053827	1	0.035006627	2	0	0	0.054944462	2	0.155563889	7	0.039744807	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K14947|0|mcf:102135367|ESRP1; epithelial splicing regulatory protein 1; K14947 epithelial splicing regulatory protein 1/2 (A)	--	[AR]	RNA processing and modification;; General function prediction only	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Epithelial splicing regulatory protein 1 GN=ESRP1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: epithelial splicing regulatory protein 1 isoform X1 [Tupaia chinensis]
ENSG00000104415(WISP1)	--	0.200969947	13	0.122543333	8	0.2171176	7	0.116152689	2	0.240746361	7	0.061063	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Insulin-like growth factor binding protein;; von Willebrand factor type C domain;; Cystine-knot domain;; Thrombospondin type 1 domain	WNT1-inducible-signaling pathway protein 1 (Precursor) GN=WISP1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: WNT1-inducible-signaling pathway protein 1 [Canis lupus familiaris]
ENSG00000104419(NDRG1)	--	101.5690853	5177	97.04938503	4939	76.00919947	3847	62.83099565	3208	29.57125188	1492	40.50591575	1982	0.002952639	-0.720999783	normal	0	-1.747363966	down	8.35E-07	-0.964530171	normal	0.000912241	-1.086826076	down	--	--	--	"K18266|0|hsa:10397|NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5; N-myc downstream regulated 1; K18266 protein NDRG1 (A)"	--	[S]	Function unknown	Ndr family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold	Protein NDRG1 GN=NDRG1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein NDRG1 [Oryctolagus cuniculus]
ENSG00000104427(ZC2HC1A)	--	6.698494256	261	7.138225618	303	8.79446524	334	6.278981641	281	6.346839909	242	6.91308641	285	0.964960833	0.07526104	normal	0.863724949	-0.343812692	normal	0.933805431	-0.236019464	normal	0.58622321	-0.173293638	normal	--	--	--	--	--	[S]	Function unknown	zinc-finger of a C2HC-type	Zinc finger C2HC domain-containing protein 1A GN=ZC2HC1A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger C2HC domain-containing protein 1A isoform 1 [Odobenus rosmarus divergens]
ENSG00000104432(IL7)	--	0.177239812	5	0.458941842	14	0.210701589	5	0.114582771	2	0.205757673	5	0.555271104	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine receptor binding (GO:0005126);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: growth factor activity (GO:0008083);; 	K05431|6.48305e-117|pps:100986540|IL7; interleukin 7; K05431 interleukin 7 (A)	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640)	--	--	Interleukin 7/9 family	Interleukin-7 (Precursor) GN=IL7 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: interleukin-7 isoform X2 [Equus caballus]
ENSG00000104442(ARMC1)	--	28.65023157	1280	25.14214187	1145	30.62194995	1366	26.77938429	1223	26.55149202	1215	23.90866301	1088	0.97872396	-0.096433232	normal	0.979555726	0.064099966	normal	0.865942029	-0.336152432	normal	0.562900738	-0.125816523	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17306|0|nle:100587062|ARMC1; armadillo repeat containing 1; K17306 armadillo repeat-containing protein 1 (A)	--	--	--	Armadillo/beta-catenin-like repeat	Armadillo repeat-containing protein 1 GN=ARMC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing protein 1 [Condylura cristata]
ENSG00000104447(TRPS1)	--	0.252392806	26	0.118916171	16	0.271584405	32	0.712661096	57	0.390875037	62	0.332282508	49	0.384547367	1.05842457	normal	0.000619785	1.838421973	up	0.929332054	0.583963959	normal	0.020484605	1.162206357	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	GATA zinc finger	Zinc finger transcription factor Trps1 GN=TRPS1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger transcription factor Trps1 [Ceratotherium simum simum]
ENSG00000104450(SPAG1)	--	6.640871248	427	6.04709984	413	6.319911908	434	7.280226316	492	6.21256262	425	7.472471394	549	0.954390607	0.173009704	normal	0.969143164	0.019822949	normal	0.859822688	0.329795683	normal	0.486597999	0.181660296	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Potential Monad-binding region of RPAP3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Sperm-associated antigen 1 GN=SPAG1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: sperm-associated antigen 1 [Odobenus rosmarus divergens]
ENSG00000104472(CHRAC1)	--	23.01913006	767	29.97235972	999	23.62728151	788	25.65577769	845	23.06303499	777	25.55725913	879	0.971818401	0.108685033	normal	0.770408598	-0.383336724	normal	0.966930093	0.149105036	normal	0.866674373	-0.051621044	normal	[K]	Transcription	--	"K11656|1.35105e-72|hsa:54108|CHRAC1, CHARC1, CHARC15, CHRAC-1, CHRAC-15, CHRAC15, YCL1; chromatin accessibility complex 1; K11656 chromatin accessibility complex protein 1 (A)"	--	[K]	Transcription	Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Chromatin accessibility complex protein 1 GN=CHRAC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: chromatin accessibility complex protein 1 [Bubalus bubalis]
ENSG00000104490(NCALD)	--	3.304523348	183	2.445571246	144	2.433569931	150	2.499706046	133	4.712248757	191	3.835875653	185	0.731404307	-0.486436488	normal	0.863692418	0.382578482	normal	0.924026308	0.291619429	normal	0.891108288	0.073421327	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF hand;; EF-hand domain;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Neurocalcin-delta GN=NCALD OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_001860 [Ailuropoda melanoleuca]
ENSG00000104497(SNX16)	--	3.944243064	136	4.08098366	159	4.8168944	155	3.74121844	119	3.00063443	118	4.192345677	149	0.95245262	-0.220808039	normal	0.820587886	-0.446714844	normal	0.966446242	-0.064604384	normal	0.568635952	-0.241801032	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17928|0|hsa:64089|SNX16; sorting nexin 16; K17928 sorting nexin-16 (A)	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	PX domain	Sorting nexin-16 GN=SNX16 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-16 isoform X1 [Camelus dromedarius]
ENSG00000104517(UBR5)	--	16.9442028	3265	16.45479471	3177	16.75019963	3192	17.98905314	3465	17.72350039	3499	15.46207417	3055	0.990482319	0.054915011	normal	0.987790708	0.117797573	normal	0.989481514	-0.071545062	normal	0.898477272	0.034997173	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: ubiquitin binding (GO:0043130);; 	"K10593|0|hsa:51366|UBR5, DD5, EDD, EDD1, HYD; ubiquitin protein ligase E3 component n-recognin 5; K10593 E3 ubiquitin-protein ligase EDD1 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	"HECT-domain (ubiquitin-transferase);; E3 ubiquitin ligase EDD;; Poly-adenylate binding protein, unique domain;; Putative zinc finger in N-recognin (UBR box)"	E3 ubiquitin-protein ligase UBR5 GN=UBR5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase UBR5 isoform 1 [Odobenus rosmarus divergens]
ENSG00000104518(GSDMD)	--	15.57577408	455	10.755149	326	12.35720233	437	15.58952394	504	19.4964319	600	16.65308418	544	0.964719	0.116351528	normal	0.000611458	0.855695014	normal	0.885488615	0.306728772	normal	0.03840529	0.415580539	normal	--	--	--	--	--	--	--	Gasdermin family;; Putative binding domain	Gasdermin-D GN=GSDMD OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: gasdermin-D isoform X1 [Tupaia chinensis] 
ENSG00000104522(TSTA3)	--	18.52774265	488	22.876709	563	21.37840267	547	26.72867058	713	29.54393113	742	20.56853712	518	0.315429565	0.514840565	normal	0.784469986	0.375975532	normal	0.969034964	-0.086634011	normal	0.276353005	0.282171192	normal	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K02377|0|hsa:7264|TSTA3, FX, P35B, SDR4E1; tissue specific transplantation antigen P35B (EC:1.1.1.271); K02377 GDP-L-fucose synthase [EC:1.1.1.271] (A)"	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[GO]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	NAD dependent epimerase/dehydratase family;; RmlD substrate binding domain;; 3-beta hydroxysteroid dehydrogenase/isomerase family	GDP-L-fucose synthase GN=TSTA3 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: GDP-L-fucose synthase isoform X1 [Galeopterus variegatus] 
ENSG00000104524(PYCRL)	--	15.34818146	697	12.46315498	580	13.220832	598	17.78872966	775	16.87450093	702	11.33848887	507	0.969069871	0.121950387	normal	0.928068828	0.253390276	normal	0.930405052	-0.245775343	normal	0.889452211	0.059067373	normal	--	--	--	K00286|0|ptr:472886|PYCRL; pyrroline-5-carboxylate reductase-like; K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] (A)	Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Pyrroline-5-carboxylate reductase dimerisation;; NADP oxidoreductase coenzyme F420-dependent	Pyrroline-5-carboxylate reductase 3 GN=PYCRL OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: pyrroline-5-carboxylate reductase 3 isoform X2 [Equus przewalskii]
ENSG00000104529(EEF1D)	--	291.507894	5878	296.1151234	5929	318.4538123	6122	352.4459566	6778	340.5554739	6620	332.6795983	6197	0.989717215	0.174659475	normal	0.991662067	0.13758264	normal	0.994410472	0.009273205	normal	0.643260708	0.1068079	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation elongation factor activity (GO:0003746);; Biological Process: translational elongation (GO:0006414);; 	K15410|0|pps:100974121|EEF1D; eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein); K15410 elongation factor 1-delta (A)	Herpes simplex infection (ko05168)	[K]	Transcription	EF-1 guanine nucleotide exchange domain;; Eukaryotic elongation factor 1 beta central acidic region	Elongation factor 1-delta GN=EEF1D OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: elongation factor 1-delta isoform X2 [Galeopterus variegatus]
ENSG00000104537(ANXA13)	--	0.202818299	6	0.749591925	23	0.06591666	1	3.905367395	125	5.24083236	164	8.984764344	281	0	4.042019868	up	2.22E-16	2.734693585	up	0	6.807396057	up	5.29E-06	4.226377408	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	"K17099|0|hsa:312|ANXA13, ANX13, ISA; annexin A13; K17099 annexin A13 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A13 GN=ANXA13 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A13 isoform X1 [Galeopterus variegatus]
ENSG00000104549(SQLE)	--	92.10209387	4354	102.254313	4853	104.2045332	4890	46.51803817	2207	49.56841628	2294	94.075282	4430	1.27E-07	-1.010575868	down	5.84E-09	-1.101926369	down	0.98885891	-0.150770198	normal	0.071077757	-0.677483469	normal	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Molecular Function: squalene monooxygenase activity (GO:0004506);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; Molecular Function: FAD binding (GO:0071949);; 	K00511|0|hsa:6713|SQLE; squalene epoxidase (EC:1.14.13.132); K00511 squalene monooxygenase [EC:1.14.13.132] (A)	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	Squalene epoxidase;; FAD binding domain;; FAD dependent oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain	Squalene monooxygenase GN=SQLE OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: squalene monooxygenase [Galeopterus variegatus]
ENSG00000104611(SH2D4A)	--	19.065445	1628	21.571448	2044	22.423195	1892	17.263915	1632	14.572095	1321	18.803729	1714	0.984683157	-0.027266205	normal	0.021981663	-0.650587463	normal	0.978149241	-0.1507098	normal	0.179905231	-0.27475612	normal	--	--	--	"K17577|0|hsa:63898|SH2D4A, PPP1R38, SH2A; SH2 domain containing 4A; K17577 SH2 domain-containing protein 4A (A)"	--	--	--	SH2 domain	SH2 domain-containing protein 4A GN=SH2D4A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: SH2 domain-containing protein 4A [Leptonychotes weddellii]
ENSG00000104613(INTS10)	--	24.2027722	1164	24.79500242	1179	24.90203734	1227	27.6623741	1332	28.21543769	1315	25.63330928	1228	0.97057344	0.163468951	normal	0.97438441	0.135907401	normal	0.981914799	-0.007107374	normal	0.675455817	0.096935937	normal	--	--	--	"K13147|0|hsa:55174|INTS10, C8orf35, INT10; integrator complex subunit 10; K13147 integrator complex subunit 10 (A)"	--	--	--	--	Integrator complex subunit 10 GN=INTS10 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: integrator complex subunit 10 [Orycteropus afer afer]
ENSG00000104626(ERI1)	--	14.16323535	927	15.24312561	1031	16.36122742	1086	17.83039196	1224	17.4299014	1142	17.17545188	1128	0.799524658	0.369595504	normal	0.97360499	0.125916218	normal	0.980004713	0.046388137	normal	0.371740413	0.177627486	normal	--	--	--	"K18416|0|hsa:90459|ERI1, 3'HEXO, HEXO, THEX1; exoribonuclease 1; K18416 3'-5' exoribonuclease 1 [EC:3.1.-.-] (A)"	--	[L]	"Replication, recombination and repair"	Exonuclease;; SAP domain	3'-5' exoribonuclease 1 GN=ERI1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: 3'-5' exoribonuclease 1 [Equus caballus]
ENSG00000104635(SLC39A14)	--	55.77692183	4216	56.2969118	4150	50.47059861	3734	54.74920852	4048	54.26794629	3953	71.36411796	5292	0.991004899	-0.089464563	normal	0.990538558	-0.091555749	normal	0.466449267	0.494630593	normal	0.70229351	0.115056433	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14720|0|hsa:23516|SLC39A14, LZT-Hs4, NET34, ZIP14, cig19; solute carrier family 39 (zinc transporter), member 14; K14720 solute carrier family 39 (zinc transporter), member 14 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP14 (Precursor) GN=SLC39A14 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP14 isoform X1 [Felis catus]
ENSG00000104643(MTMR9)	--	5.239748181	571	4.981091255	568	4.481216976	502	4.503199125	490	4.44694367	506	4.138047027	473	0.927000945	-0.250811835	normal	0.951773622	-0.187650403	normal	0.967475197	-0.093847317	normal	0.465023311	-0.181226263	normal	--	--	--	K18084|0|ptr:472697|MTMR9; myotubularin related protein 9; K18084 myotubularin-related protein 9 (A)	--	[R]	General function prediction only	Myotubularin-like phosphatase domain	Myotubularin-related protein 9 GN=MTMR9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: myotubularin-related protein 9 isoformX1 [Canis lupus familiaris]
ENSG00000104660(LEPROTL1)	--	32.12372975	1099	30.03094481	1138	32.474784	1169	38.92493606	1306	42.87531601	1375	36.51978612	1289	0.956256709	0.217851603	normal	0.943871257	0.251200436	normal	0.975013013	0.132522571	normal	0.289076977	0.199938293	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Vacuolar protein sorting 55	Leptin receptor overlapping transcript-like 1 GN=LEPROTL1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: leptin receptor overlapping transcript-like 1 [Trichechus manatus latirostris]
ENSG00000104671(DCTN6)	--	39.110916	665	40.454027	684	39.36860566	661	39.368307	673	35.485208	600	40.271287	685	0.974799367	-0.013548983	normal	0.947311625	-0.209964306	normal	0.974257071	0.043065484	normal	0.843804337	-0.059045379	normal	--	--	--	K10428|6.68616e-137|ptr:472730|DCTN6; dynactin 6; K10428 dynactin 6 (A)	Vasopressin-regulated water reabsorption (ko04962)	[UZ]	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	Bacterial transferase hexapeptide (six repeats)	Dynactin subunit 6 GN=DCTN6 OS=Homo sapiens (Human) PE=1 SV=1	UZ	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	PREDICTED: dynactin subunit 6 [Erinaceus europaeus]
ENSG00000104679(R3HCC1)	--	16.07529	506	15.25717772	515	12.83632057	459	20.953695	678	20.36334293	702	16.49631247	531	0.746857777	0.390288741	normal	0.661456173	0.424400788	normal	0.947523733	0.201309109	normal	0.078026293	0.346726316	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[S]	Function unknown	R3H domain	R3H and coiled-coil domain-containing protein 1 GN=R3HCC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: R3H and coiled-coil domain-containing protein 1 isoform X1 [Tupaia chinensis]
ENSG00000104687(GSR)	--	118.1459053	6047	127.0543655	6590	112.3628997	5729	78.75090522	4061	86.5135653	4398	83.37537492	4272	0.070145883	-0.605027856	normal	0.089325519	-0.604686316	normal	0.757123014	-0.431530727	normal	0.000213997	-0.54988814	normal	[C]	Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00383|0|pps:100977327|GSR; glutathione reductase; K00383 glutathione reductase (NADPH) [EC:1.8.1.7] (A)	Glutathione metabolism (ko00480);; Thyroid hormone synthesis (ko04918)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain;; Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD dependent oxidoreductase;; FAD binding domain"	"Glutathione reductase, mitochondrial (Precursor) GN=GSR OS=Homo sapiens (Human) PE=1 SV=2"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: glutathione reductase, mitochondrial isoform X1 [Condylura cristata]"
ENSG00000104689(TNFRSF10A)	--	14.05339363	1048	14.61135823	1105	16.61430549	1143	17.46421693	1324	16.04783846	1153	18.07370918	1332	0.901269359	0.306032235	normal	0.979940921	0.039866173	normal	0.958872829	0.212216904	normal	0.333752481	0.187559565	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K04722|0|hsa:8797|TNFRSF10A, APO2, CD261, DR4, TRAILR-1, TRAILR1; tumor necrosis factor receptor superfamily, member 10a; K04722 tumor necrosis factor receptor superfamily member 10 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; Measles (ko05162);; Influenza A (ko05164)	--	--	Death domain;; TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 10A (Precursor) GN=TNFRSF10A OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 10A [Lipotes vexillifer]
ENSG00000104691(UBXN8)	--	8.373269763	194	9.770671201	228	7.739215152	182	8.2687803	194	8.709819086	203	7.758396618	187	0.966707394	-0.03059	normal	0.949380029	-0.187660615	normal	0.966792304	0.030557878	normal	0.885930031	-0.070135856	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	UBX domain	UBX domain-containing protein 8 GN=UBXN8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: UBX domain-containing protein 8 [Galeopterus variegatus]
ENSG00000104695(PPP2CB)	--	49.43410849	1546	51.85790213	1682	51.56732363	1578	54.43827063	1705	45.88622378	1425	49.4731167	1534	0.980882987	0.110294758	normal	0.945007943	-0.260387654	normal	0.983725466	-0.049042493	normal	0.795679398	-0.064909864	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K04382|0|hgl:101726191|Ppp2cb; protein phosphatase 2, catalytic subunit, beta isozyme; K04382 serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16] (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform GN=PPP2CB OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: serine/threonine-protein phosphatase 2A catalytic subunit beta isoform [Orycteropus afer afer]
ENSG00000104714(ERICH1)	--	10.96356378	506	8.543015	398	10.11233107	468	10.68226179	493	9.56039539	439	9.092204	424	0.969615902	-0.068172276	normal	0.962319904	0.119593158	normal	0.959035596	-0.150225476	normal	0.915769982	-0.038483687	normal	--	--	--	--	--	--	--	--	Glutamate-rich protein 1 GN=ERICH1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: glutamate-rich protein 1 isoform X1 [Tupaia chinensis]
ENSG00000104722(NEFM)	--	0.275450688	25	0.309108032	34	0.278034503	29	0.010873421	1	0.032040689	2	0.032699626	3	0.001151252	-3.407708885	down	3.70E-05	-3.354199349	down	0.003060184	-2.764156338	down	6.49E-08	-3.89269629	down	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	K04573|0|ggo:101124623|NEFM; neurofilament medium polypeptide isoform 1; K04573 neurofilament medium polypeptide (neurofilament 3) (A)	Amyotrophic lateral sclerosis (ALS) (ko05014)	--	--	Intermediate filament protein;; Intermediate filament head (DNA binding) region	Neurofilament medium polypeptide GN=NEFM OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	neurofilament medium polypeptide [Bos taurus] 
ENSG00000104723(TUSC3)	--	73.04342782	1754	73.8048965	1840	69.76437663	1671	64.08487255	1619	66.10764807	1600	76.04723111	1808	0.977742975	-0.146244634	normal	0.96247964	-0.2228638	normal	0.982119966	0.105299866	normal	0.704308168	-0.087748283	normal	--	--	Biological Process: cell redox homeostasis (GO:0045454);; 	K12669|0|mcf:102133600|TUSC3; tumor suppressor candidate 3; K12669 oligosaccharyltransferase complex subunit gamma (A)	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	OST3 / OST6 family;; Thioredoxin	Tumor suppressor candidate 3 (Precursor) GN=TUSC3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tumor suppressor candidate 3 [Galeopterus variegatus]
ENSG00000104728(ARHGEF10)	--	15.83719574	1853	16.88062046	1874	17.37916358	1966	16.9195865	1888	15.64527114	1762	13.36354825	1508	0.986245775	-0.003833232	normal	0.981927299	-0.110241819	normal	0.775327434	-0.390574247	normal	0.399020087	-0.164124495	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K16727|0|hsa:9639|ARHGEF10, GEF10, SNCV; Rho guanine nucleotide exchange factor (GEF) 10; K16727 Rho guanine nucleotide exchange factor 10 (A)"	--	[T]	Signal transduction mechanisms	RhoGEF domain	Rho guanine nucleotide exchange factor 10 GN=ARHGEF10 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 10 isoform X5 [Tupaia chinensis]
ENSG00000104731(KLHDC4)	--	14.42578754	800	15.91956201	960	15.66214403	927	13.641603	859	13.5913141	843	13.590783	893	0.975241986	0.071692981	normal	0.953627392	-0.208577404	normal	0.977012842	-0.062097383	normal	0.78854852	-0.071288824	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Kelch motif"	Kelch domain-containing protein 4 GN=KLHDC4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: kelch domain-containing protein 4 [Galeopterus variegatus]
ENSG00000104738(MCM4)	--	61.71361065	4730	61.0789654	4718	70.08415573	5410	70.48069406	5414	65.41033227	4961	52.90158668	4053	0.988656595	0.16397263	normal	0.992648787	0.051013034	normal	0.772098346	-0.424792175	normal	0.811018345	-0.064146151	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; Molecular Function: ATPase activity (GO:0016887);; 	"K02212|0|hsa:4173|MCM4, CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21; minichromosome maintenance complex component 4 (EC:3.6.4.12); K02212 DNA replication licensing factor MCM4 [EC:3.6.4.12] (A)"	DNA replication (ko03030);; Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; MCM N-terminal domain;; Magnesium chelatase, subunit ChlI;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA)"	DNA replication licensing factor MCM4 GN=MCM4 OS=Homo sapiens (Human) PE=1 SV=5	L	"Replication, recombination and repair"	PREDICTED: DNA replication licensing factor MCM4 [Oryctolagus cuniculus]
ENSG00000104756(KCTD9)	--	33.72139684	1945	27.75826932	1638	31.4190256	1784	23.79787392	1407	20.07864749	1152	19.46812819	1124	0.348531463	-0.497515733	normal	0.244448885	-0.528635972	normal	0.01037113	-0.674038615	normal	8.87E-05	-0.565141109	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	Pentapeptide repeats (8 copies);; Pentapeptide repeats (9 copies);; BTB/POZ domain;; Domain of unknown function (DUF3354);; Pentapeptide repeats (9 copies);; BTB/POZ domain	BTB/POZ domain-containing protein KCTD9 GN=KCTD9 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD9 isoform X1 [Tupaia chinensis]
ENSG00000104760(FGL1)	--	2.682336089	80	3.332135786	90	1.181627587	29	7.31174764	236	12.14587973	378	19.13050737	583	2.28E-08	1.512189483	up	0	2.030902372	up	0	4.25169583	up	0.001914829	2.568472251	up	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Fibrinogen-like protein 1 (Precursor) GN=FGL1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: fibrinogen-like protein 1 [Bison bison bison]
ENSG00000104763(ASAH1)	--	88.42281977	2972	100.5321594	3456	87.65227897	2851	95.43055614	3423	87.38439946	3058	156.4140815	5523	0.982941625	0.172911572	normal	0.979633472	-0.197849262	normal	1.65E-06	0.945325896	normal	0.522028729	0.35147347	normal	--	--	--	K12348|0|mcc:703699|ASAH1; N-acylsphingosine amidohydrolase (acid ceramidase) 1; K12348 acid ceramidase [EC:3.5.1.23] (A)	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071);; Lysosome (ko04142)	--	--	"Linear amide C-N hydrolases, choloylglycine hydrolase family;; beta subunit of N-acylethanolamine-hydrolyzing acid amidase"	Acid ceramidase subunit beta (Precursor) GN=ASAH1 OS=Homo sapiens (Human) PE=1 SV=5	G	Carbohydrate transport and metabolism	PREDICTED: acid ceramidase [Ceratotherium simum simum]
ENSG00000104765(BNIP3L)	--	61.94816436	3227	62.918482	3416	59.97053968	3198	57.43942885	3114	37.1584709	1990	52.330517	2859	0.989263644	-0.082217044	normal	0.000354249	-0.800495825	normal	0.982636138	-0.169865756	normal	0.161961662	-0.327237372	normal	--	--	Cellular Component: mitochondrial envelope (GO:0005740);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: positive regulation of apoptotic process (GO:0043065);; 	K15465|7.84263e-101|hgl:101709497|Bnip3l; BCL2/adenovirus E1B 19kDa interacting protein 3-like; K15465 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (A)	--	--	--	BNIP3	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like GN=BNIP3L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like isoform X1 [Physeter catodon]
ENSG00000104774(MAN2B1)	--	59.951022	1948	61.72912012	1864	60.799531	1833	62.6849888	1992	67.359032	2104	70.253764	2088	0.986736116	0.001390622	normal	0.978865535	0.153189253	normal	0.975106975	0.179484651	normal	0.6099114	0.110479857	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: alpha-mannosidase activity (GO:0004559);; Biological Process: mannose metabolic process (GO:0006013);; 	"K12311|0|hsa:4125|MAN2B1, LAMAN, MANB; mannosidase, alpha, class 2B, member 1 (EC:3.2.1.24); K12311 lysosomal alpha-mannosidase [EC:3.2.1.24] (A)"	Other glycan degradation (ko00511);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolases family 38 C-terminal domain;; Glycosyl hydrolases family 38 N-terminal domain;; Alpha mannosidase, middle domain"	Lysosomal alpha-mannosidase E peptide (Precursor) GN=MAN2B1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: lysosomal alpha-mannosidase [Tupaia chinensis]
ENSG00000104783(KCNN4)	--	40.81363	1445	30.69105327	1148	35.04009011	1296	34.246281	1243	32.10040844	1153	23.1492981	847	0.946724273	-0.247791045	normal	0.980642565	-0.01513679	normal	0.04027409	-0.621019965	normal	0.274648206	-0.284277379	normal	--	--	Molecular Function: calmodulin binding (GO:0005516);; Biological Process: potassium ion transport (GO:0006813);; Molecular Function: calcium-activated potassium channel activity (GO:0015269);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: small conductance calcium-activated potassium channel activity (GO:0016286);; 	"K04945|0|hsa:3783|KCNN4, IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4; K04945 potassium intermediate/small conductance calcium-activated channel subfamily N member 4 (A)"	Insulin secretion (ko04911);; Salivary secretion (ko04970);; Protein digestion and absorption (ko04974)	[P]	Inorganic ion transport and metabolism	Calcium-activated SK potassium channel;; Calmodulin binding domain;; Ion channel	Intermediate conductance calcium-activated potassium channel protein 4 GN=KCNN4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: intermediate conductance calcium-activated potassium channel protein 4 [Tupaia chinensis] 
ENSG00000104804(TULP2)	--	0	0	0	0	0	0	0	0	0.028355017	0	0.061445701	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Tub family	Tubby-related protein 2 GN=TULP2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: tubby-related protein 2 isoform X4 [Mustela putorius furo] 
ENSG00000104805(NUCB1)	--	101.0548384	5021	98.15168001	4702	94.9027574	4863	93.41426455	4516	90.18805063	4501	86.0747989	4469	0.9863164	-0.183702191	normal	0.991632298	-0.084427775	normal	0.990123345	-0.130143757	normal	0.527901597	-0.134323048	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[R]	General function prediction only	EF-hand domain pair;; EF hand	Nucleobindin-1 (Precursor) GN=NUCB1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: nucleobindin-1 [Galeopterus variegatus] 
ENSG00000104808(DHDH)	--	2.047507821	86	1.642869763	96	1.807798392	102	1.354212042	115	1.371260936	76	1.919768183	100	0.91441397	0.382466938	normal	0.933618176	-0.352210386	normal	0.97044852	-0.036316779	normal	0.991325506	0.013495176	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; 	"K00078|0|hsa:27294|DHDH, 2DD, HUM2DD; dihydrodiol dehydrogenase (dimeric) (EC:1.3.1.20 1.1.1.179); K00078 dihydrodiol dehydrogenase / D-xylose 1-dehydrogenase (NADP) [EC:1.3.1.20 1.1.1.179] (A)"	Pentose and glucuronate interconversions (ko00040);; Metabolism of xenobiotics by cytochrome P450 (ko00980)	[GQ]	"Carbohydrate transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	"Oxidoreductase family, NAD-binding Rossmann fold"	"Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase GN=DHDH OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [Eptesicus fuscus]"
ENSG00000104812(GYS1)	--	22.395865	1564	20.34468478	1427	21.51429875	1478	22.17224096	1539	17.41303248	1199	15.00824739	1047	0.983503188	-0.05402604	normal	0.933444876	-0.272264997	normal	0.311283347	-0.505059135	normal	0.23911269	-0.262074173	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: glycogen (starch) synthase activity (GO:0004373);; Biological Process: glycogen biosynthetic process (GO:0005978);; 	K00693|0|ptr:456196|GYS1; glycogen synthase 1 (muscle); K00693 glycogen(starch) synthase [EC:2.4.1.11] (A)	Starch and sucrose metabolism (ko00500);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Glycogen synthase;; Glycosyl transferase 4-like domain;; Starch synthase catalytic domain;; Glycosyl transferases group 1	"Glycogen [starch] synthase, muscle GN=GYS1 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"glycogen [starch] synthase, muscle [Equus caballus] "
ENSG00000104814(MAP4K1)	--	0.571421671	42	0.300538654	22	0.462126297	28	0.185607914	13	0.337383011	17	0.465201074	29	0.061627734	-1.611206455	normal	0.984223952	-0.364794124	normal	0.985274236	0.040201063	normal	0.348094045	-0.659817361	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04408|0|hsa:11184|MAP4K1, HPK1; mitogen-activated protein kinase kinase kinase kinase 1 (EC:2.7.11.1); K04408 mitogen-activated protein kinase kinase kinase kinase 1 [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein kinase domain;; CNH domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase kinase 1 GN=MAP4K1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase kinase 1 [Balaenoptera acutorostrata scammoni]
ENSG00000104818(CGB2)	--	0	0	0	0	0	0	0.17706922	2	0.178688	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10045|2.71205e-87|hsa:114336|CGB2; chorionic gonadotropin, beta polypeptide 2; K10045 chorionic gonadotropin, beta polypeptide (A)"	--	--	--	Cystine-knot domain	Choriogonadotropin subunit beta (Precursor) GN=CGB8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	RecName: Full=Lutropin/choriogonadotropin subunit beta; AltName: Full=LSH-B/CG-B; AltName: Full=Luteinizing hormone subunit beta; AltName: Full=Lutropin/choriogonadotropin beta chain; Flags: Precursor [Equus burchellii] 
ENSG00000104823(ECH1)	--	509.5552275	11875	486.5210609	11711	479.0727107	11507	401.5279311	10553	412.2676051	10572	454.8915849	11158	0.99202548	-0.201078972	normal	0.993594709	-0.169019516	normal	0.996406519	-0.052717706	normal	0.538605332	-0.141475348	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	"K12663|0|hsa:1891|ECH1, HPXEL; enoyl CoA hydratase 1, peroxisomal; K12663 delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase [EC:5.3.3.-] (A)"	Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial (Precursor) GN=ECH1 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial [Myotis lucifugus]"
ENSG00000104825(NFKBIB)	--	29.79726	999	36.13375	1258	32.60102236	1143	35.08685946	1187	35.25385468	1181	32.218184	1113	0.95433945	0.217623753	normal	0.976646385	-0.112410016	normal	0.980217985	-0.046600768	normal	0.971851655	0.01257585	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K02581|1.34806e-172|pps:100980612|NFKBIB; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta; K02581 NF-kappa-B inhibitor beta (A)"	Chemokine signaling pathway (ko04062);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Neurotrophin signaling pathway (ko04722);; Adipocytokine signaling pathway (ko04920);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	NF-kappa-B inhibitor beta GN=NFKBIB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: NF-kappa-B inhibitor beta [Galeopterus variegatus]
ENSG00000104826(LHB)	--	0.750965	3	0	0	0.23207	0	0.94003	4	0.487238	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08521|2.82045e-91|hsa:3972|LHB, CGB4, LSH-B, hLHB; luteinizing hormone beta polypeptide; K08521 luteinizing hormone beta polypeptide (A)"	Neuroactive ligand-receptor interaction (ko04080);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Prolactin signaling pathway (ko04917)	--	--	Cystine-knot domain	Lutropin subunit beta (Precursor) GN=LHB OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	lutropin subunit beta precursor [Ailuropoda melanoleuca] 
ENSG00000104827(CGB3)	--	0.0889584	1	0	0	0.174561	1	0.268651	3	0.4513383	4	0.0905752	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10045|4.00276e-90|hsa:93659|CGB5, HCG; chorionic gonadotropin, beta polypeptide 5; K10045 chorionic gonadotropin, beta polypeptide (A)"	--	--	--	Cystine-knot domain	Choriogonadotropin subunit beta variant 2 (Precursor) GN=CGB2 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: lutropin subunit beta [Bos mutus]
ENSG00000104833(TUBB4A)	--	15.240648	631	10.41355481	391	14.71398881	629	13.242613	527	13.954746	596	7.934220036	364	0.900790423	-0.28989564	normal	0.149573787	0.584872393	normal	0.001802324	-0.794868924	normal	0.759660309	-0.172498657	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	K07375|0|ssc:100736584|tubulin beta-4A chain-like; K07375 tubulin beta (A)	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta-4A chain GN=TUBB4A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tubulin beta-4A chain [Camelus bactrianus]
ENSG00000104835(SARS2)	--	89.78913328	3550	84.98265353	3454	90.36780235	3663	63.0812631	2568	67.42950918	2660	64.01936323	2555	0.397591883	-0.497751546	normal	0.812971683	-0.398069164	normal	0.264379117	-0.52773152	normal	0.001228852	-0.475850507	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01875|0|hsa:54938|SARS2, SARS, SARSM, SERS, SYS, SerRS, SerRSmt, mtSerRS; seryl-tRNA synthetase 2, mitochondrial (EC:6.1.1.11); K01875 seryl-tRNA synthetase [EC:6.1.1.11] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetase class II core domain (G, H, P, S and T)"	"Serine--tRNA ligase, mitochondrial (Precursor) GN=SARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: serine--tRNA ligase, mitochondrial [Lipotes vexillifer]"
ENSG00000104848(KCNA7)	--	0.150235	13	0.088674	8	0.0330801	2	0.240418	21	0.450205	39	0.11464	10	0.980308599	0.6044329	normal	0.007516246	2.071172514	up	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04880|0|hsa:3743|KCNA7, HAK6, KV1.7; potassium voltage-gated channel, shaker-related subfamily, member 7; K04880 potassium voltage-gated channel Shaker-related subfamily A member 7 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily A member 7 GN=KCNA7 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily A member 7 [Leptonychotes weddellii]
ENSG00000104852(SNRNP70)	--	169.2836718	5331	160.714139	5300	165.4772598	5559	133.979674	4368	143.6164015	4544	129.5492318	4157	0.947013904	-0.318164084	normal	0.977548962	-0.243380995	normal	0.766881073	-0.427439116	normal	0.044870444	-0.330172683	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K11093|2.09982e-110|pale:102884204|SNRNP70; small nuclear ribonucleoprotein 70kDa (U1); K11093 U1 small nuclear ribonucleoprotein 70kDa (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"U1 small nuclear ribonucleoprotein of 70kDa MW N terminal;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	U1 small nuclear ribonucleoprotein 70 kDa GN=SNRNP70 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	"PREDICTED: U1 small nuclear ribonucleoprotein 70 kDa, partial [Loxodonta africana]"
ENSG00000104853(CLPTM1)	--	94.055927	4717	95.56290341	4749	96.36449	4780	91.46916462	4451	91.922586	4548	106.075414	5321	0.990780502	-0.11453395	normal	0.991715677	-0.083790791	normal	0.989804684	0.146351439	normal	0.967999994	-0.013172102	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Cleft lip and palate transmembrane protein 1 (CLPTM1)	Cleft lip and palate transmembrane protein 1 GN=CLPTM1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cleft lip and palate transmembrane protein 1 [Ochotona princeps]
ENSG00000104856(RELB)	--	14.2587331	604	12.5551539	542	12.76468455	558	10.18934637	435	10.8426743	458	14.22389995	606	0.3781393	-0.502850547	normal	0.919282546	-0.263570702	normal	0.967664388	0.110473857	normal	0.406125815	-0.205150773	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09253|0|hsa:5971|RELB, I-REL, IREL, REL-B; v-rel avian reticuloendotheliosis viral oncogene homolog B; K09253 transcription factor RelB (A)"	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Osteoclast differentiation (ko04380);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169)	--	--	Rel homology domain (RHD)	Transcription factor RelB GN=RELB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	TPA: reticuloendotheliosis viral oncogene homolog B-like [Bos taurus]
ENSG00000104859(CLASRP)	--	20.45958289	987	19.15370187	971	18.72787238	960	16.7481841	796	18.2372001	894	19.07665522	922	0.847736572	-0.340522301	normal	0.969479155	-0.140395057	normal	0.977193571	-0.066452271	normal	0.37678598	-0.180578942	normal	--	--	--	"K13168|6.62506e-137|pps:100991840|CLASRP; CLK4-associating serine/arginine rich protein; K13168 splicing factor, arginine/serine-rich 16 (A)"	--	[A]	RNA processing and modification	Alternative splicing regulator	CLK4-associating serine/arginine rich protein GN=CLASRP OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: CLK4-associating serine/arginine rich protein isoform X5 [Canis lupus familiaris]
ENSG00000104863(LIN7B)	--	8.403652	107	6.632486	81	7.446818083	97	3.730630115	56	4.253080233	54	3.61701606	48	0.089479858	-0.945833575	normal	0.824487793	-0.592740185	normal	0.081641542	-1.000618243	normal	0.032041459	-0.872553268	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	PDZ domain (Also known as DHR or GLGF);; L27 domain	Protein lin-7 homolog B GN=LIN7B OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	protein lin-7 homolog B [Sus scrofa]
ENSG00000104866(PPP1R37)	--	14.593032	993	16.827823	1167	13.21829	946	16.10847	1099	17.283318	1171	18.96925	1311	0.974635614	0.115323846	normal	0.980811785	-0.016468738	normal	0.495146429	0.461834322	normal	0.349696621	0.184381648	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17576|0|ggo:101153844|PPP1R37; protein phosphatase 1 regulatory subunit 37; K17576 protein phosphatase 1 regulatory subunit 37 (A)	--	[A]	RNA processing and modification	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Protein phosphatase 1 regulatory subunit 37 GN=PPP1R37 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 37 isoform X2 [Galeopterus variegatus]
ENSG00000104870(FCGRT)	--	32.50602786	797	34.31132934	727	27.95817167	687	17.75725911	436	23.1307321	581	19.96767815	489	6.53E-05	-0.898703478	normal	0.841381435	-0.344041328	normal	0.383749911	-0.497462678	normal	0.000742342	-0.574883985	normal	--	--	--	--	--	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain"	IgG receptor FcRn large subunit p51 (Precursor) GN=FCGRT OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: IgG receptor FcRn large subunit p51 isoform X2 [Galeopterus variegatus]
ENSG00000104872(PIH1D1)	--	38.33734231	779	43.1663286	807	45.76943185	830	54.3856421	1052	53.12311913	1047	47.85606938	934	0.711910862	0.401922868	normal	0.832302615	0.353611095	normal	0.965487597	0.161741819	normal	0.08222236	0.306685317	normal	--	--	--	--	--	[S]	Function unknown	pre-RNA processing PIH1/Nop17	PIH1 domain-containing protein 1 GN=PIH1D1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: PIH1 domain-containing protein 1 isoform X2 [Canis lupus familiaris]
ENSG00000104879(CKM)	--	0	0	0	0	0	0	0	0	0	0	0.0306894	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: kinase activity (GO:0016301);; Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	"K00933|0|ptr:744935|CKM; creatine kinase, muscle; K00933 creatine kinase [EC:2.7.3.2] (A)"	Arginine and proline metabolism (ko00330)	[C]	Energy production and conversion	"ATP:guanido phosphotransferase, C-terminal catalytic domain;; ATP:guanido phosphotransferase, N-terminal domain"	"Creatine kinase M-type, N-terminally processed GN=CKM OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	PREDICTED: creatine kinase M-type [Felis catus] 
ENSG00000104880(ARHGEF18)	--	9.067227857	967	9.300944914	941	9.885566131	1072	20.77146847	2176	28.03513855	2812	21.72862163	2230	1.74E-09	1.138021663	up	0	1.55638532	up	5.89E-08	1.047400253	up	1.47E-10	1.255514886	up	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain	Rho guanine nucleotide exchange factor 18 GN=ARHGEF18 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 18 [Galeopterus variegatus]
ENSG00000104881(PPP1R13L)	--	9.327420019	482	9.156954906	443	7.85751	464	16.88361114	889	9.33332	547	13.7934006	556	0.0002125	0.850293293	normal	0.906960535	0.281940065	normal	0.926410252	0.251917624	normal	0.221858602	0.497345086	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Ankyrin repeats (3 copies);; Ankyrin repeat;; Variant SH3 domain;; Ankyrin repeats (many copies);; SH3 domain;; Ankyrin repeat;; Ankyrin repeats (many copies);; Variant SH3 domain	RelA-associated inhibitor GN=PPP1R13L OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: relA-associated inhibitor [Leptonychotes weddellii]
ENSG00000104883(PEX11G)	--	3.742752	56	3.733312	57	1.405322	23	1.400595	25	1.295261098	18	2.792303	48	0.243992333	-1.146028199	normal	0.007876704	-1.60467614	down	0.614384196	1.006372418	normal	0.533590558	-0.600167377	normal	--	--	Cellular Component: integral component of peroxisomal membrane (GO:0005779);; Biological Process: peroxisome fission (GO:0016559);; 	K13353|4.34751e-136|mcf:102143093|PEX11G; peroxisomal biogenesis factor 11 gamma; K13353 peroxin-11C (A)	Peroxisome (ko04146)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Peroxisomal biogenesis factor 11 (PEX11)	Peroxisomal membrane protein 11C GN=PEX11G OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein 11C [Panthera tigris altaica]
ENSG00000104884(ERCC2)	--	8.801397579	651	7.891716873	622	10.86014061	661	10.80197231	763	12.37938358	732	8.2880118	602	0.952951751	0.197761799	normal	0.947042041	0.213024655	normal	0.964158504	-0.142835658	normal	0.721808438	0.094963267	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Molecular Function: ATP binding (GO:0005524);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: ATP-dependent helicase activity (GO:0008026);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; "	"K10844|0|hsa:2068|ERCC2, COFS2, EM9, TFIIH, TTD, XPD; excision repair cross-complementation group 2 (EC:3.6.4.12); K10844 DNA excision repair protein ERCC-2 [EC:3.6.4.12] (A)"	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420)	[KL]	"Transcription;; Replication, recombination and repair"	Protein of unknown function (DUF1227);; Helicase C-terminal domain;; DEAD_2	TFIIH basal transcription factor complex helicase XPD subunit GN=ERCC2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: TFIIH basal transcription factor complex helicase XPD subunit isoform X1 [Galeopterus variegatus] 
ENSG00000104885(DOT1L)	--	4.668632	617	4.505692904	630	5.241544719	704	5.490704128	785	5.847644	803	6.468924	944	0.876822939	0.315891139	normal	0.865074291	0.327922884	normal	0.674679323	0.414149072	normal	0.047588429	0.355635661	normal	--	--	Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; 	"K11427|0|hsa:84444|DOT1L, DOT1, KMT4; DOT1-like histone H3K79 methyltransferase (EC:2.1.1.43); K11427 histone-lysine N-methyltransferase, H3 lysine-79 specific [EC:2.1.1.43] (A)"	Lysine degradation (ko00310);; Transcriptional misregulation in cancer (ko05202)	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	Histone methylation protein DOT1	"Histone-lysine N-methyltransferase, H3 lysine-79 specific GN=DOT1L OS=Homo sapiens (Human) PE=1 SV=2"	B	Chromatin structure and dynamics	"PREDICTED: histone-lysine N-methyltransferase, H3 lysine-79 specific [Ceratotherium simum simum]"
ENSG00000104886(PLEKHJ1)	--	21.358877	414	21.575302	429	21.246578	436	30.9387328	607	27.648377	530	24.20833194	462	0.32168246	0.519632274	normal	0.906302284	0.282690184	normal	0.968228987	0.075020463	normal	0.167859803	0.300186904	normal	--	--	--	--	--	--	--	PH domain	Pleckstrin homology domain-containing family J member 1 GN=PLEKHJ1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family J member 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000104888(SLC17A7)	--	0.964601205	47	0.2373185	12	0.402014077	20	0.359775378	17	0.423213651	21	0.602783104	31	0.105715676	-1.417769144	normal	0.97262599	0.716933044	normal	0.964954581	0.588016947	normal	0.896143991	-0.215013617	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12302|0|pps:100972690|SLC17A7; solute carrier family 17 (vesicular glutamate transporter), member 7; K12302 MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8 (A)"	Synaptic vesicle cycle (ko04721);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Nicotine addiction (ko05033)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Vesicular glutamate transporter 1 GN=SLC17A7 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: vesicular glutamate transporter 1 [Mustela putorius furo] 
ENSG00000104889(RNASEH2A)	--	35.72750105	703	30.95160093	627	38.6497015	787	32.5579007	659	29.59070108	580	25.67670121	509	0.967831073	-0.123798955	normal	0.964382653	-0.133504193	normal	0.042175883	-0.63545876	normal	0.13134065	-0.29795885	normal	[L]	"Replication, recombination and repair"	--	"K10743|0|hsa:10535|RNASEH2A, AGS4, JUNB, RNASEHI, RNHIA, RNHL; ribonuclease H2, subunit A (EC:3.1.26.4); K10743 ribonuclease H2 subunit A [EC:3.1.26.4] (A)"	DNA replication (ko03030)	[L]	"Replication, recombination and repair"	Ribonuclease HII	Ribonuclease H2 subunit A GN=RNASEH2A OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: ribonuclease H2 subunit A [Ceratotherium simum simum]
ENSG00000104892(KLC3)	--	0.401612	14	0.16092482	4	0.3312701	11	0.342327749	10	0.583647672	20	0.144705858	5	--	--	--	0.500946244	1.946705866	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	"K10407|0|hsa:147700|KLC3, KLC2, KLC2L, KLCt, KNS2B; kinesin light chain 3; K10407 kinesin light chain (A)"	Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Rabaptin-like protein;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Soluble NSF attachment protein, SNAP"	Kinesin light chain 3 GN=KLC3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin light chain 3 [Galeopterus variegatus]
ENSG00000104894(CD37)	--	1.74588	41	2.863485	67	2.296813	58	1.169606	28	2.359787	59	1.3410736	33	0.951504603	-0.555676384	normal	0.968508527	-0.20005698	normal	0.754204267	-0.794081895	normal	0.419100504	-0.488566292	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06475|8.12798e-175|nle:100596765|CD37; CD37 molecule; K06475 CD37 antigen (A)	Hematopoietic cell lineage (ko04640)	[R]	General function prediction only	Tetraspanin family	Leukocyte antigen CD37 GN=CD37 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leukocyte antigen CD37 isoform X1 [Galeopterus variegatus] 
ENSG00000104897(SF3A2)	--	28.1172762	1478	27.29795067	1503	26.207858	1495	27.64094179	1485	27.81057136	1488	27.17530082	1609	0.983739639	-0.023990722	normal	0.983234901	-0.035860777	normal	0.981320958	0.097632183	normal	0.971576238	0.01281356	normal	[A]	RNA processing and modification	--	"K12826|1.30595e-112|ptr:455568|SF3A2; splicing factor 3a, subunit 2, 66kDa; K12826 splicing factor 3A subunit 2 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Zinc-finger of C2H2 type	Splicing factor 3A subunit 2 GN=SF3A2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: splicing factor 3A subunit 2 [Canis lupus familiaris]
ENSG00000104901(DKKL1)	--	2.127231	22	1.206108	16	1.119417	13	0.14466	2	0.763396	4	0.226075	1	0.03153028	-2.757656153	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Dickkopf-like protein 1 (Precursor) GN=DKKL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: dickkopf-like protein 1 isoform X2 [Mustela putorius furo] 
ENSG00000104903(LYL1)	--	0.113280687	3	0.29271419	8	0.0351614	0	0.4068022	13	0.266951885	7	0.183938472	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K15604|1.33958e-130|hsa:4066|LYL1, bHLHa18; lymphoblastic leukemia associated hematopoiesis regulator 1; K15604 protein lyl-1 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Protein lyl-1 GN=LYL1 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: protein lyl-1 [Galeopterus variegatus]
ENSG00000104904(OAZ1)	--	222.9466	3804	218.93564	3807	235.7362906	4151	309.8997967	5370	309.521889	5321	290.28163	5040	0.607139792	0.466413337	normal	0.652801213	0.461460565	normal	0.968116673	0.271583434	normal	0.010970908	0.398268678	normal	--	--	Molecular Function: ornithine decarboxylase inhibitor activity (GO:0008073);; 	K16548|3.84477e-139|nle:100580887|OAZ1; ornithine decarboxylase antizyme 1; K16548 ornithine decarboxylase antizyme 1 (A)	--	[E]	Amino acid transport and metabolism	Ornithine decarboxylase antizyme	Ornithine decarboxylase antizyme 1 GN=OAZ1 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	ornithine decarboxylase antizyme 1 [Sus scrofa] 
ENSG00000104907(TRMT1)	--	12.43637001	407	11.93436	479	10.91283109	406	11.576233	391	9.293393003	402	16.2946916	525	0.966044685	-0.08835212	normal	0.912630124	-0.273313406	normal	0.814804608	0.361359489	normal	0.989067348	0.008239161	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: tRNA (guanine-N2-)-methyltransferase activity (GO:0004809);; Biological Process: tRNA processing (GO:0008033);; Molecular Function: metal ion binding (GO:0046872);; 	"K00555|0|hsa:55621|TRMT1, TRM1; tRNA methyltransferase 1 homolog (S. cerevisiae) (EC:2.1.1.216); K00555 tRNA (guanine26-N2/guanine27-N2)-dimethyltransferase [EC:2.1.1.215 2.1.1.216] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	"N2,N2-dimethylguanosine tRNA methyltransferase;; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Met-10+ like-protein"	tRNA (guanine(26)-N(2))-dimethyltransferase GN=TRMT1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (guanine(26)-N(2))-dimethyltransferase [Galeopterus variegatus]
ENSG00000104915(STX10)	--	28.42914402	657	25.71620337	599	27.1704981	650	29.45600056	675	31.14145002	716	32.0405222	738	0.974795613	0.008143081	normal	0.93752589	0.235432772	normal	0.959131244	0.174508389	normal	0.569938768	0.138802282	normal	--	--	Cellular Component: membrane (GO:0016020);; Biological Process: Golgi vesicle transport (GO:0048193);; 	K08498|1.82449e-170|pps:100989116|STX10; syntaxin 10; K08498 syntaxin 6 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Syntaxin 6, N-terminal;; SNARE domain"	Syntaxin-10 GN=STX10 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-10 isoform X2 [Pteropus alecto]
ENSG00000104936(DMPK)	--	37.83748581	2844	39.10471623	2733	38.86050511	2814	38.19942363	2721	41.92275719	2967	38.8369184	3047	0.98763819	-0.094564535	normal	0.987440417	0.097041365	normal	0.987497763	0.106420755	normal	0.894182217	0.037161276	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08788|0|pon:100434494|DMPK, DMWD; dystrophia myotonica-protein kinase; K08788 dystrophia myotonica-protein kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; DMPK coiled coil domain like;; Kinase-like	Myotonin-protein kinase GN=DMPK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: myotonin-protein kinase isoform X4 [Bos taurus] 
ENSG00000104941(RSPH6A)	--	0	0	0	0	0	0	0.0365766	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Radial spokehead-like protein	Radial spoke head protein 6 homolog A GN=RSPH6A OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: radial spoke head protein 6 homolog A [Galeopterus variegatus]
ENSG00000104946(TBC1D17)	--	20.42623618	879	22.03182	974	21.057265	930	11.16697772	492	13.028293	557	19.62155	857	0.000129074	-0.865983422	normal	0.000431916	-0.825951963	normal	0.971332358	-0.126013425	normal	0.043875424	-0.565629699	normal	[R]	General function prediction only	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3548);; Rab-GTPase-TBC domain	TBC1 domain family member 17 GN=TBC1D17 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TBC1 domain family member 17 isoform 1 [Sus scrofa]
ENSG00000104951(IL4I1)	--	49.00380463	3269	48.10804722	3257	53.07709082	3526	51.42259596	3417	50.5277994	3312	47.93084705	3116	0.990803728	0.033033421	normal	0.990601888	0.002731138	normal	0.981677457	-0.186543516	normal	0.843804337	-0.051336189	normal	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; Molecular Function: FAD binding (GO:0071949);; 	"K03334|0|hsa:259307|IL4I1, FIG1, LAAO, LAO; interleukin 4 induced 1 (EC:1.4.3.2); K03334 L-amino-acid oxidase [EC:1.4.3.2] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Cysteine and methionine metabolism (ko00270);; Valine, leucine and isoleucine degradation (ko00280);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Tryptophan metabolism (ko00380);; Phenylalanine, tyrosine and tryptophan biosynthesis (ko00400)"	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Flavin containing amine oxidoreductase;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; FAD binding domain;; HI0933-like protein;; Pyridine nucleotide-disulphide oxidoreductase;; Alanine dehydrogenase/PNT, C-terminal domain;; Thi4 family;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase"	L-amino-acid oxidase (Precursor) GN=IL4I1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: L-amino-acid oxidase [Orcinus orca]
ENSG00000104953(TLE6)	--	9.74144147	113	5.802042015	68	9.5412868	96	2.488482581	34	1.456150444	36	3.537136594	34	2.58E-06	-1.718393574	down	0.448943955	-0.910666373	normal	0.000462927	-1.465316314	down	0.0003235	-1.434249396	down	[R]	General function prediction only	--	--	--	[B]	Chromatin structure and dynamics	"WD domain, G-beta repeat"	Transducin-like enhancer protein 6 GN=TLE6 OS=Homo sapiens (Human) PE=2 SV=2	B	Chromatin structure and dynamics	PREDICTED: transducin-like enhancer protein 6 [Myotis brandtii]
ENSG00000104957(CCDC130)	--	8.372118024	238	6.721563842	190	9.062980358	236	5.959487281	184	8.847502845	269	9.3100376	294	0.819398987	-0.399148235	normal	0.656136761	0.476975094	normal	0.897819662	0.306972136	normal	0.735995131	0.150372957	normal	[S]	Function unknown	--	K13115|0|hsa:81576|CCDC130; coiled-coil domain containing 130; K13115 coiled-coil domain-containing protein 130 (A)	--	[S]	Function unknown	Family of unknown function (DUF572)	Coiled-coil domain-containing protein 130 GN=CCDC130 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 130 isoform X1 [Galeopterus variegatus] 
ENSG00000104960(PTOV1)	--	103.6553582	2679	93.93719858	2524	99.50363791	2726	77.87371484	2112	96.147262	2525	90.4549394	2389	0.837869237	-0.373674976	normal	0.988489859	-0.020842595	normal	0.975916122	-0.198552395	normal	0.284865775	-0.19510364	normal	--	--	--	--	--	--	--	Mediator complex subunit 25 PTOV activation and synapsin 2	Prostate tumor-overexpressed gene 1 protein GN=PTOV1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: prostate tumor-overexpressed gene 1 protein isoform X1 [Galeopterus variegatus]
ENSG00000104964(AES)	--	143.425562	4292	136.26484	4152	137.30391	4320	112.206543	3523	107.829384	3329	130.452778	4083	0.940708097	-0.315552939	normal	0.920286991	-0.34000551	normal	0.991085357	-0.089660896	normal	0.163947142	-0.243859076	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[B]	Chromatin structure and dynamics	Groucho/TLE N-terminal Q-rich domain	Amino-terminal enhancer of split GN=AES OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: amino-terminal enhancer of split [Physeter catodon]
ENSG00000104967(NOVA2)	--	1.486426579	213	0.583076808	84	0.802755653	115	0.832375499	118	1.289147935	183	0.306714233	44	0.012577035	-0.874295744	normal	0.001013648	1.088363946	up	0.000368576	-1.364253969	down	0.839424806	-0.278997451	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K14944|6.19535e-175|hgl:101700992|Nova2; neuro-oncological ventral antigen 2; K14944 RNA-binding protein Nova (A)	--	[AR]	RNA processing and modification;; General function prediction only	KH domain;; KH domain;; KH domain;; KH domain	RNA-binding protein Nova-2 GN=NOVA2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein Nova-2 isoform X2 [Erinaceus europaeus]
ENSG00000104969(SGTA)	--	35.082417	1571	33.4339391	1510	34.87199616	1576	38.62073267	1735	39.08038625	1764	36.0239355	1647	0.980924539	0.112315671	normal	0.966982265	0.202687492	normal	0.983894606	0.055229733	normal	0.563509026	0.122779601	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K16365|0|ptr:100609678|SGTA; small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha; K16365 small glutamine-rich tetratricopeptide repeat-containing protein alpha (A)"	--	[R]	General function prediction only	Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Plant specific mitochondrial import receptor subunit TOM20	Small glutamine-rich tetratricopeptide repeat-containing protein alpha GN=SGTA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: small glutamine-rich tetratricopeptide repeat-containing protein alpha [Ceratotherium simum simum]
ENSG00000104973(MED25)	--	30.81285869	1584	27.14466446	1388	28.72918222	1529	26.12649194	1454	29.5292133	1453	24.02213273	1351	0.975151662	-0.154221125	normal	0.982444716	0.044553132	normal	0.968531113	-0.186655637	normal	0.652212058	-0.101379515	normal	--	--	--	K15168|0|pon:100444927|MED25; mediator complex subunit 25; K15168 mediator of RNA polymerase II transcription subunit 25 (A)	--	--	--	Mediator complex subunit 25 von Willebrand factor type A;; Mediator complex subunit 25 PTOV activation and synapsin 2;; Mediator complex subunit 25 synapsin 1;; Mediator complex subunit 25 C-terminal NR box-containing	Mediator of RNA polymerase II transcription subunit 25 GN=MED25 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 25 isoform X10 [Mustela putorius furo]
ENSG00000104976(SNAPC2)	--	14.488123	412	11.79771672	340	13.106562	382	9.62620657	274	11.03051156	313	8.673201375	247	0.127347208	-0.61646029	normal	0.957703927	-0.14014871	normal	0.112615982	-0.634205479	normal	0.041188078	-0.464620318	normal	--	--	--	"K15209|2.05129e-178|hsa:6618|SNAPC2, PTFDELTA, SNAP45; small nuclear RNA activating complex, polypeptide 2, 45kDa; K15209 snRNA-activating protein complex subunit 2 (A)"	--	--	--	Small nuclear RNA activating complex subunit 2-like	snRNA-activating protein complex subunit 2 GN=SNAPC2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: snRNA-activating protein complex subunit 2 [Ceratotherium simum simum]
ENSG00000104980(TIMM44)	--	13.6849864	548	13.7685152	543	13.9590587	563	13.31825293	505	12.40780344	497	16.481458	608	0.960881689	-0.148291484	normal	0.96007746	-0.148699844	normal	0.968614524	0.102380271	normal	0.850199793	-0.05949325	normal	--	--	--	"K17804|0|hsa:10469|TIMM44, TIM44; translocase of inner mitochondrial membrane 44 homolog (yeast); K17804 mitochondrial import inner membrane translocase subunit TIM44 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim44-like domain	Mitochondrial import inner membrane translocase subunit TIM44 (Precursor) GN=TIMM44 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit TIM44 [Galeopterus variegatus]
ENSG00000104983(CCDC61)	--	4.339917874	124	3.956895124	105	4.057525079	131	2.738119815	86	3.713373067	118	2.298368265	56	0.744773118	-0.550523406	normal	0.962818774	0.145000191	normal	0.001138638	-1.212319123	down	0.220464286	-0.491178513	normal	--	--	--	K16755|0|cjc:100413543|CCDC61; coiled-coil domain containing 61; K16755 coiled-coil domain-containing protein 61 (A)	--	--	--	--	Coiled-coil domain-containing protein 61 GN=CCDC61 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 61 [Camelus bactrianus]
ENSG00000104998(IL27RA)	--	3.574887087	220	3.255904039	203	3.609520883	221	3.091757623	189	3.376991	205	2.437642031	151	0.934909357	-0.248078082	normal	0.965800125	-0.007228788	normal	0.508067189	-0.55318168	normal	0.446596436	-0.262436557	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain	Interleukin-27 receptor subunit alpha (Precursor) GN=IL27RA OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-27 receptor subunit alpha [Odobenus rosmarus divergens]
ENSG00000105011(ASF1B)	--	16.80280291	598	16.00590124	547	17.78470263	618	25.27291193	887	20.94408302	719	16.75682081	580	0.218239519	0.53681737	normal	0.79250558	0.372124558	normal	0.969165787	-0.099593761	normal	0.32539467	0.287935307	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: chromatin assembly or disassembly (GO:0006333);; 	K10753|1.12312e-131|pps:100968584|ASF1B; anti-silencing function 1B histone chaperone; K10753 histone chaperone ASF1 (A)	--	[KB]	Transcription;; Chromatin structure and dynamics	ASF1 like histone chaperone	Histone chaperone ASF1B GN=ASF1B OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone chaperone ASF1B [Camelus ferus] 
ENSG00000105048(TNNT1)	--	105.400678	1828	83.19352692	1524	92.1330123	1733	36.15529884	666	42.57339654	740	30.61874116	563	4.44E-16	-1.485343433	down	1.11E-07	-1.062145382	down	0	-1.627729892	down	2.19E-24	-1.390255799	down	--	--	Cellular Component: troponin complex (GO:0005861);; 	"K10372|1.52945e-91|mcc:698339|TNNT1; troponin T type 1 (skeletal, slow); K10372 troponin T, slow skeletal muscle (A)"	--	[Z]	Cytoskeleton	Troponin	"Troponin T, slow skeletal muscle GN=TNNT1 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: troponin T, slow skeletal muscle isoform X1 [Orycteropus afer afer]"
ENSG00000105053(VRK3)	--	17.842681	600	17.464911	631	17.0607959	633	18.157259	652	17.381234	610	24.733394	857	0.970542718	0.088858891	normal	0.971268683	-0.070086468	normal	0.630492023	0.427916421	normal	0.579891698	0.16462187	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08816|0|ptr:456230|VRK3; vaccinia related kinase 3 (EC:2.7.11.1); K08816 vaccinia related kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; zinc-ribbon domain;; Protein tyrosine kinase;; zinc-ribbon domain	Inactive serine/threonine-protein kinase VRK3 GN=VRK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inactive serine/threonine-protein kinase VRK3 isoform X1 [Equus caballus] 
ENSG00000105058(FAM32A)	--	36.930454	953	35.184079	888	40.779328	1074	41.340171	1098	43.363322	1127	41.092388	1075	0.965432217	0.173237322	normal	0.880932338	0.321941699	normal	0.980422197	-0.006939009	normal	0.450802468	0.158036794	normal	--	--	--	"K13120|6.84252e-64|ptr:455808|FAM32A; family with sequence similarity 32, member A; K13120 protein FAM32A (A)"	--	[S]	Function unknown	Eukaryotic family of unknown function (DUF1754)	Protein FAM32A GN=FAM32A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM32A [Orycteropus afer afer]
ENSG00000105063(PPP6R1)	--	45.68080873	4076	49.38740828	4459	49.30780729	4518	55.8214808	4936	52.822809	4674	53.21560844	4765	0.975469239	0.245271965	normal	0.992376295	0.046495574	normal	0.992298443	0.06847818	normal	0.589424023	0.117953144	normal	--	--	--	"K15499|0|hsa:22870|PPP6R1, KIAA1115, PP6R1, SAP190, SAPS1; protein phosphatase 6, regulatory subunit 1; K15499 serine/threonine-protein phosphatase 6 regulatory subunit 1 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	SIT4 phosphatase-associated protein	Serine/threonine-protein phosphatase 6 regulatory subunit 1 GN=PPP6R1 OS=Homo sapiens (Human) PE=1 SV=5	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 1 isoform X1 [Galeopterus variegatus] 
ENSG00000105072(C19orf44)	--	2.0243196	153	1.781558	133	1.40889	107	1.51574	114	1.6577887	123	2.311369001	142	0.825493976	-0.450072991	normal	0.962147766	-0.132625839	normal	0.886356028	0.395125867	normal	0.900709545	-0.073318351	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4614)	Uncharacterized protein C19orf44 GN=C19orf44 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C19orf44 homolog isoform X4 [Galeopterus variegatus] 
ENSG00000105085(MED26)	--	25.112509	861	26.6619972	874	24.65248747	809	23.56062201	825	24.49739211	848	28.03699077	896	0.973968627	-0.092283126	normal	0.975620137	-0.064881593	normal	0.968897592	0.138820911	normal	0.985893701	-0.006956966	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K15169|0|hsa:9441|MED26, CRSP7, CRSP70; mediator complex subunit 26; K15169 mediator of RNA polymerase II transcription subunit 26 (A)"	--	[K]	Transcription	TFIIS helical bundle-like domain	Mediator of RNA polymerase II transcription subunit 26 GN=MED26 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 26 isoform X1 [Sus scrofa]
ENSG00000105088(OLFM2)	--	5.94764731	210	4.710028989	181	5.648853531	186	3.090591761	97	5.33321542	164	2.642306	88	0.000146026	-1.132656576	down	0.955714272	-0.162295172	normal	0.000957386	-1.075015453	down	0.013014991	-0.746516095	normal	--	--	--	--	--	[W]	Extracellular structures	Olfactomedin-like domain;; Neurogenesis glycoprotein	Noelin-2 (Precursor) GN=OLFM2 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: noelin-2 isoform X2 [Eptesicus fuscus]
ENSG00000105122(RASAL3)	--	0	0	0	0	0.0125871	0	0	0	0	0	0.032235478	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of GTPase activity (GO:0043087);; 	K17634|0|hsa:64926|RASAL3; RAS protein activator like 3; K17634 RAS protein activator-like 3 (A)	Ras signaling pathway (ko04014)	[R]	General function prediction only	GTPase-activator protein for Ras-like GTPase	RAS protein activator like-3 GN=RASAL3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: RAS protein activator like-3 isoform 2 [Ceratotherium simum simum]
ENSG00000105127(AKAP8)	--	7.0348019	535	8.180782	618	6.484054	499	7.140053	536	8.369294	627	7.132329	541	0.972091476	-0.028057653	normal	0.973466101	-0.000566576	normal	0.96668883	0.107982967	normal	0.952688398	0.023348045	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	"K16525|0|hsa:10270|AKAP8, AKAP_95, AKAP-8, AKAP-95, AKAP95; A kinase (PRKA) anchor protein 8; K16525 A-kinase anchor protein 8 (A)"	--	--	--	A-kinase anchoring protein 95 (AKAP95)	A-kinase anchor protein 8 GN=AKAP8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: A-kinase anchor protein 8 [Orcinus orca]
ENSG00000105131(EPHX3)	--	0.035658926	1	0	0	0	0	0.071261087	2	0.104128533	2	0.070553891	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[I]	Lipid transport and metabolism	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Epoxide hydrolase 3 (Precursor) GN=EPHX3 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: epoxide hydrolase 3 [Felis catus]
ENSG00000105135(ILVBL)	--	23.33138728	857	25.26891411	907	23.64564894	848	19.80943807	647	21.08875574	689	19.63788501	716	0.601176969	-0.435459863	normal	0.676265833	-0.417224201	normal	0.932276372	-0.2519066	normal	0.035228864	-0.369077015	normal	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: thiamine pyrophosphate binding (GO:0030976);; 	"K11259|0|hsa:10994|ILVBL, 209L8, AHAS, ILV2H; ilvB (bacterial acetolactate synthase)-like (EC:2.2.1.-); K11259 acetolactate synthase-like protein [EC:2.2.1.-] (A)"	--	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	"Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;; Thiamine pyrophosphate enzyme, central domain"	Acetolactate synthase-like protein GN=ILVBL OS=Homo sapiens (Human) PE=1 SV=2	EH	Amino acid transport and metabolism;; Coenzyme transport and metabolism	PREDICTED: acetolactate synthase-like protein isoform X1 [Mustela putorius furo] 
ENSG00000105136(ZNF419)	--	8.958235	211	10.78772749	227	8.1166948	237	5.892523057	189	7.273639688	210	9.720217697	312	0.951266689	-0.188239758	normal	0.95832275	-0.132809327	normal	0.809347078	0.386213236	normal	0.92800877	0.055405688	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:79744|ZNF419, ZNF419A; zinc finger protein 419; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2H2-type zinc-finger domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 419 GN=ZNF419 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 419 [Physeter catodon]
ENSG00000105137(SYDE1)	--	10.191606	572	12.127653	723	12.6683323	747	12.475558	747	11.0646374	663	12.2764498	763	0.822128948	0.353428053	normal	0.964233843	-0.146094096	normal	0.976158904	0.022238824	normal	0.81162932	0.06874008	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain	Rho GTPase-activating protein SYDE1 GN=SYDE1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein SYDE1 [Leptonychotes weddellii]
ENSG00000105146(AURKC)	--	0.168970852	3	0.158829938	3	0.450428326	2	0.242191619	4	0.224910119	3	0.701002704	6	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K11480|0|hsa:6795|AURKC, AIE2, AIK3, ARK3, AurC, SPGF5, STK13, aurora-C; aurora kinase C (EC:2.7.11.1); K11480 aurora kinase C [EC:2.7.11.1] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase	Aurora kinase C GN=AURKC OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: aurora kinase C isoform X2 [Galeopterus variegatus]
ENSG00000105171(POP4)	--	23.7950753	1078	24.55033264	993	25.00184262	972	29.22759549	1128	26.51222942	1131	29.15822932	1095	0.980246402	0.034529516	normal	0.967201814	0.16606964	normal	0.967674311	0.163371601	normal	0.595231857	0.119027832	normal	--	--	Cellular Component: ribonuclease MRP complex (GO:0000172);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: ribonuclease activity (GO:0004540);; Biological Process: rRNA processing (GO:0006364);; Biological Process: mRNA cleavage (GO:0006379);; Biological Process: tRNA processing (GO:0008033);; Cellular Component: ribonuclease P complex (GO:0030677);; 	"K03538|1.82029e-151|hsa:10775|POP4, RPP29; processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) (EC:3.1.26.5); K03538 ribonuclease P protein subunit POP4 [EC:3.1.26.5] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[A]	RNA processing and modification	Domain of unknown function UPF0086	Ribonuclease P protein subunit p29 GN=POP4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribonuclease P protein subunit p29 [Oryctolagus cuniculus]
ENSG00000105173(CCNE1)	--	19.21725567	650	18.00471098	611	19.836665	721	21.13619745	715	23.28344046	791	13.83122727	458	0.969908605	0.106431344	normal	0.832276005	0.350314852	normal	0.027645088	-0.661187803	normal	0.954960941	-0.03513345	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	"K06626|0|hsa:898|CCNE1, CCNE; cyclin E1; K06626 cyclin E (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Hepatitis B (ko05161);; Measles (ko05162);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206);; Prostate cancer (ko05215);; Small cell lung cancer (ko05222)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G1/S-specific cyclin-E1 GN=CCNE1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: G1/S-specific cyclin-E1-like [Tupaia chinensis]
ENSG00000105176(URI1)	--	63.242549	3255	61.20659702	3090	62.78739	3174	59.91929812	3179	60.79334782	3153	53.22208581	2760	0.989915934	-0.064885797	normal	0.990226018	0.007688049	normal	0.97614646	-0.209818003	normal	0.705814122	-0.087777502	normal	--	--	--	"K17560|0|ptr:744003|URI1; URI1, prefoldin-like chaperone; K17560 unconventional prefoldin RPB5 interactor 1 (A)"	--	[S]	Function unknown	Prefoldin subunit;; Prefoldin subunit	Unconventional prefoldin RPB5 interactor 1 GN=URI1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: unconventional prefoldin RPB5 interactor 1 [Galeopterus variegatus]
ENSG00000105185(PDCD5)	--	163.683728	1637	148.33392	1589	175.83093	1865	222.375371	2321	187.033303	1900	167.545864	1773	0.475355388	0.472485854	normal	0.958329746	0.236247892	normal	0.984089738	-0.081206992	normal	0.304074025	0.213782229	normal	[R]	General function prediction only	Molecular Function: DNA binding (GO:0003677);; 	K06875|9.68615e-76|ptr:455920|PDCD5; programmed cell death 5; K06875 programmed cell death protein 5 (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Double-stranded DNA-binding domain	Programmed cell death protein 5 GN=PDCD5 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: programmed cell death protein 5-like isoform X2 [Mustela putorius furo]
ENSG00000105186(ANKRD27)	--	19.1269828	1744	18.75593237	1760	22.14369581	1844	17.47914501	1620	14.774274	1390	15.88283102	1498	0.978782892	-0.137113115	normal	0.841282293	-0.361566607	normal	0.91271472	-0.307811863	normal	0.114291652	-0.267910123	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Vacuolar sorting protein 9 (VPS9) domain	Ankyrin repeat domain-containing protein 27 GN=ANKRD27 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ankyrin repeat domain-containing protein 27 isoform X2 [Physeter catodon]
ENSG00000105193(RPS16)	--	4087.821534	22947	3827.73308	22298	3769.81463	22283	3908.86382	23287	4063.941564	22867	3458.921289	19999	0.998160558	-0.009612385	normal	0.998009188	0.014925234	normal	0.996420214	-0.164295281	normal	0.873246221	-0.051312799	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02960|2.13136e-95|ptr:456023|RPS16; ribosomal protein S16; K02960 small subunit ribosomal protein S16e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S9/S16	40S ribosomal protein S16 GN=RPS16 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S16 isoform X1 [Lipotes vexillifer]
ENSG00000105197(TIMM50)	--	94.04357587	2159	96.04803924	2195	102.5863092	2372	111.2352907	2536	99.69110515	2289	91.23546663	2094	0.97392394	0.201227006	normal	0.987199618	0.039043623	normal	0.975680051	-0.188006346	normal	0.9508736	0.019191172	normal	--	--	--	"K17496|0|hsa:92609|TIMM50, TIM50, TIM50L; translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae); K17496 mitochondrial import inner membrane translocase subunit TIM50 (A)"	--	[K]	Transcription	NLI interacting factor-like phosphatase	Mitochondrial import inner membrane translocase subunit TIM50 (Precursor) GN=TIMM50 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: mitochondrial import inner membrane translocase subunit TIM50, partial [Mustela putorius furo] "
ENSG00000105202(FBL)	--	399.825515	6258	373.7505999	5923	393.6626697	6258	455.121415	7419	417.5184591	6483	366.6248198	5776	0.986623034	0.214642376	normal	0.992708967	0.108880351	normal	0.992167262	-0.123891186	normal	0.776970155	0.071924572	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Biological Process: rRNA processing (GO:0006364);; Biological Process: tRNA processing (GO:0008033);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: tRNA (adenine-N1-)-methyltransferase activity (GO:0016429);; Biological Process: tRNA methylation (GO:0030488);; Cellular Component: tRNA (m1A) methyltransferase complex (GO:0031515);; 	K14563|5.14804e-178|bacu:103006881|FBL; fibrillarin; K14563 rRNA 2'-O-methyltransferase fibrillarin [EC:2.1.1.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	Fibrillarin;; tRNA methyltransferase complex GCD14 subunit	rRNA 2'-O-methyltransferase fibrillarin GN=FBL OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: rRNA 2'-O-methyltransferase fibrillarin [Balaenoptera acutorostrata scammoni]
ENSG00000105204(DYRK1B)	--	14.67863071	609	16.10820796	693	13.222001	571	12.1027719	494	17.0160572	736	22.31180672	953	0.855405208	-0.331831902	normal	0.973264829	0.065285604	normal	0.004287262	0.729183188	normal	0.723241561	0.201453758	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08825|0|hsa:9149|DYRK1B, AOMS3, MIRK; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B (EC:2.7.12.1); K08825 dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Dual specificity tyrosine-phosphorylation-regulated kinase 1B GN=DYRK1B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1B isoform X3 [Canis lupus familiaris]
ENSG00000105219(CNTD2)	--	0.4608931	9	0.0728911	2	0.359232785	9	0.375839063	4	0.110619671	2	0.311958261	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin N-terminal domain-containing protein 2 GN=CNTD2 OS=Homo sapiens (Human) PE=2 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: cyclin N-terminal domain-containing protein 2 [Physeter catodon]
ENSG00000105220(GPI)	--	672.1518324	25901	744.2396828	26115	694.5241814	24495	471.4490887	19932	341.2178114	13852	448.3984922	18196	0.937469459	-0.408725854	normal	7.44E-06	-0.936135224	normal	0.89352203	-0.437125962	normal	0.000723818	-0.579458964	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: glucose-6-phosphate isomerase activity (GO:0004347);; Biological Process: gluconeogenesis (GO:0006094);; Biological Process: glycolytic process (GO:0006096);; 	"K01810|0|hsa:2821|GPI, AMF, GNPI, NLK, PGI, PHI, SA-36, SA36; glucose-6-phosphate isomerase (EC:5.3.1.9); K01810 glucose-6-phosphate isomerase [EC:5.3.1.9] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520);; Carbon metabolism (ko01200)	[G]	Carbohydrate transport and metabolism	Phosphoglucose isomerase	Glucose-6-phosphate isomerase GN=GPI OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: glucose-6-phosphate isomerase isoform 1 [Ceratotherium simum simum]
ENSG00000105221(AKT2)	--	82.64192282	5220	78.12726462	5184	81.76260675	5510	77.65574587	5435	85.2806136	5346	85.52819301	5711	0.993662701	0.027390064	normal	0.993401554	0.022960966	normal	0.993745774	0.043387926	normal	0.915753721	0.030523479	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04456|0|ptr:456035|AKT2; v-akt murine thymoma viral oncogene homolog 2; K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Tight junction (ko04530);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Carbohydrate digestion and absorption (ko04973);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PH domain;; Kinase-like;; Protein kinase C terminal domain	RAC-beta serine/threonine-protein kinase GN=AKT2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: RAC-beta serine/threonine-protein kinase [Bubalus bubalis]
ENSG00000105223(PLD3)	--	206.942338	5821	174.329383	5143	171.9010672	5049	164.5646512	4658	193.3581883	5439	192.0390477	5553	0.921442169	-0.35228444	normal	0.993017894	0.059287761	normal	0.991109858	0.128941438	normal	0.837914133	-0.053828108	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; 	"K16860|0|hsa:23646|PLD3, AD19, HU-K4, HUK4; phospholipase D family, member 3 (EC:3.1.4.4); K16860 phospholipase D3/4 [EC:3.1.4.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565)	[R]	General function prediction only	PLD-like domain;; PLD-like domain;; Phospholipase D Active site motif	Phospholipase D3 GN=PLD3 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	phospholipase D3 [Sus scrofa]
ENSG00000105227(PRX)	--	2.205992629	230	2.135410053	223	2.090658091	232	0.888974132	95	1.303577106	132	1.116600874	116	2.87E-06	-1.292578018	down	0.05519163	-0.771054923	normal	0.001042292	-0.998898085	normal	0.000114655	-1.018354021	down	[N]	Cell motility	--	--	--	--	--	PDZ domain (Also known as DHR or GLGF)	Periaxin GN=PRX OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: periaxin [Ursus maritimus]
ENSG00000105229(PIAS4)	--	6.50003	389	6.8316	415	7.88188	485	5.84123	350	5.87072	352	7.85092	475	0.950671259	-0.182487144	normal	0.921824631	-0.257940525	normal	0.970792568	-0.038228225	normal	0.633530087	-0.151092985	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K16065|0|hsa:51588|PIAS4, PIASY, Piasg, ZMIZ6; protein inhibitor of activated STAT, 4; K16065 E3 SUMO-protein ligase PIAS4 [EC:6.3.2.-] (A)"	NF-kappa B signaling pathway (ko04064);; Ubiquitin mediated proteolysis (ko04120);; Jak-STAT signaling pathway (ko04630)	[K]	Transcription	PINIT domain;; MIZ/SP-RING zinc finger;; SAP domain;; Zinc-finger of the MIZ type in Nse subunit	E3 SUMO-protein ligase PIAS4 GN=PIAS4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: E3 SUMO-protein ligase PIAS4 [Odobenus rosmarus divergens]
ENSG00000105245(NUMBL)	--	24.0162265	1455	24.71618279	1406	22.31488662	1338	18.71939727	1051	16.67486252	955	11.07386569	629	0.33189946	-0.499465097	normal	0.106319337	-0.578690218	normal	2.76E-08	-1.095388241	down	0.00030837	-0.694941877	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06057|0|ggo:101149149|NUMBL; numb-like protein; K06057 numb (A)	Notch signaling pathway (ko04330)	[T]	Signal transduction mechanisms	NUMB domain;; Phosphotyrosine interaction domain (PTB/PID);; Phosphotyrosine-binding domain	Numb-like protein GN=NUMBL OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: numb-like protein isoform X1 [Galeopterus variegatus]
ENSG00000105246(EBI3)	--	3.4469	58	2.52517	43	2.79073	48	3.70533	63	6.06838	103	5.24692	90	0.975834204	0.086273556	normal	0.00673143	1.210489443	up	0.291501616	0.878082548	normal	0.083831787	0.760741129	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain	Interleukin-27 subunit beta (Precursor) GN=EBI3 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: interleukin-27 subunit beta isoform X3 [Canis lupus familiaris]
ENSG00000105248(CCDC94)	--	7.906614388	256	8.636472718	281	7.908818639	261	6.701154647	218	7.632973434	246	7.33329382	239	0.926745604	-0.26094852	normal	0.94188205	-0.212117221	normal	0.959112125	-0.134515843	normal	0.532933219	-0.203807851	normal	--	--	--	--	--	[S]	Function unknown	Family of unknown function (DUF572)	Coiled-coil domain-containing protein 94 GN=CCDC94 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 94 isoform X1 [Galeopterus variegatus]
ENSG00000105251(SHD)	--	0.0229102	1	0.0221163	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SH2 domain	SH2 domain-containing adapter protein D GN=SHD OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH2 domain-containing adapter protein D [Galeopterus variegatus]
ENSG00000105254(TBCB)	--	155.0925797	2674	167.958165	2910	162.621211	3080	140.5865258	2439	133.564433	2330	124.7821975	2044	0.981268401	-0.163443589	normal	0.899815296	-0.341916719	normal	0.062067814	-0.599462683	normal	0.017491819	-0.368278432	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein binding (GO:0005515);; 	"K17262|1.72233e-158|ptr:455974|TBCB, CKAP1; tubulin folding cofactor B; K17262 tubulin-folding cofactor B (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-like domain;; CAP-Gly domain	Tubulin-folding cofactor B GN=TBCB OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin-folding cofactor B [Oryctolagus cuniculus]
ENSG00000105255(FSD1)	--	9.055373421	304	5.148474655	188	7.644005411	277	4.777028666	178	6.555501921	242	4.439023708	159	0.012493442	-0.797690448	normal	0.880706436	0.340428639	normal	0.015980563	-0.803287104	normal	0.304715972	-0.430404644	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPRY domain;; Fibronectin type III domain	Fibronectin type III and SPRY domain-containing protein 1 GN=FSD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: fibronectin type III and SPRY domain-containing protein 1 isoform X1 [Myotis lucifugus]
ENSG00000105258(POLR2I)	--	46.2024	570	40.4281	510	46.5043	593	43.3195	553	41.7319	518	38.0968	477	0.970444939	-0.074311324	normal	0.971340208	0.001025276	normal	0.869320344	-0.32141845	normal	0.615203379	-0.13347108	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: zinc ion binding (GO:0008270);; "	"K03017|1.46352e-90|umr:103682534|POLR2I; polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa; K03017 DNA-directed RNA polymerase II subunit RPB9 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerases M/15 Kd subunit;; Transcription factor S-II (TFIIS)	DNA-directed RNA polymerase II subunit RPB9 GN=POLR2I OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"DNA-directed RNA polymerase II subunit RPB9, partial [Bos mutus]"
ENSG00000105261(OVOL3)	--	0.130696	1	0	0	0	0	0.134356601	1	0.397297268	2	0.264125	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09216|6.50895e-155|ptr:748222|OVOL3; ovo-like zinc finger 3; K09216 ovo (A)	--	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Putative transcription factor ovo-like protein 3 GN=OVOL3 OS=Homo sapiens (Human) PE=5 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: putative transcription factor ovo-like protein 3 [Vicugna pacos]
ENSG00000105270(CLIP3)	--	4.483675	368	7.512061091	509	4.91231825	355	2.743618041	235	2.5673264	244	5.915341	588	0.06326999	-0.674322125	normal	3.32E-06	-1.077479281	down	0.011943351	0.71730686	normal	0.817602045	-0.226267007	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	K10423|0|pps:100983298|CLIP3; CAP-GLY domain containing linker protein 3; K10423 CAP-Gly domain-containing linker protein 3/4 (A)	--	[ZR]	Cytoskeleton;; General function prediction only	CAP-Gly domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	CAP-Gly domain-containing linker protein 3 GN=CLIP3 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: CAP-Gly domain-containing linker protein 3 [Sorex araneus]
ENSG00000105281(SLC1A5)	--	191.6302081	8880	202.5062203	9698	185.1333343	8920	134.920161	6321	121.2025104	5674	220.8602578	10309	0.410088538	-0.521131675	normal	0.000573206	-0.79458362	normal	0.990929854	0.200465697	normal	0.435367877	-0.321838101	normal	[C]	Energy production and conversion	Molecular Function: symporter activity (GO:0015293);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05616|0|ptr:456155|SLC1A5; solute carrier family 1 (neutral amino acid transporter), member 5; K05616 solute carrier family 1 (neutral amino acid transporter), member 5 (A)"	Protein digestion and absorption (ko04974);; Central carbon metabolism in cancer (ko05230)	[E]	Amino acid transport and metabolism	Sodium:dicarboxylate symporter family	Neutral amino acid transporter B(0) GN=SLC1A5 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: neutral amino acid transporter B(0) [Mustela putorius furo] 
ENSG00000105287(PRKD2)	--	20.8540625	1119	18.82041233	901	29.74388782	1362	23.4985824	1298	20.08308256	1134	17.377953	1041	0.96611397	0.183014616	normal	0.894682812	0.309930499	normal	0.739775798	-0.395544143	normal	0.974413286	0.017026934	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; Biological Process: intracellular signal transduction (GO:0035556);; "	"K06070|0|hsa:25865|PRKD2, PKD2, nPKC-D2; protein kinase D2 (EC:2.7.11.13); K06070 protein kinase D [EC:2.7.11.13] (A)"	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; PH domain;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase D2 GN=PRKD2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase D2 [Galeopterus variegatus]
ENSG00000105289(TJP3)	--	1.305913889	90	0.9487706	65	0.704150518	49	0.189040612	13	0.84185593	53	1.3974674	80	2.95E-10	-2.683613869	down	0.959808204	-0.307925195	normal	0.737441179	0.682292759	normal	0.624851727	-0.500191349	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06097|0|hsa:27134|TJP3, ZO-3, ZO3; tight junction protein 3; K06097 tight junction protein 3 (A)"	Tight junction (ko04530)	[T]	Signal transduction mechanisms	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Variant SH3 domain;; Guanylate kinase	Tight junction protein ZO-3 GN=TJP3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tight junction protein ZO-3 isoform X1 [Galeopterus variegatus]
ENSG00000105290(APLP1)	--	59.56910315	3049	54.47144407	2733	52.01633055	2756	26.23163658	1356	33.72550964	1690	23.37557893	1188	5.99E-11	-1.198879068	down	0.004282767	-0.714380942	normal	2.87E-11	-1.221281037	down	8.77E-15	-1.033339376	down	--	--	Molecular Function: heparin binding (GO:0008201);; Molecular Function: transition metal ion binding (GO:0046914);; 	"K05639|0|hsa:333|APLP1, APLP; amyloid beta (A4) precursor-like protein 1; K05639 amyloid beta (A4) precursor-like protein 1 (A)"	--	[R]	General function prediction only	"E2 domain of amyloid precursor protein;; Amyloid A4 N-terminal heparin-binding;; beta-amyloid precursor protein C-terminus;; Copper-binding of amyloid precursor, CuBD"	C30 (Precursor) GN=APLP1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: amyloid-like protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000105298(CACTIN)	--	8.148121	601	7.2117566	508	8.8887568	593	8.260454	587	8.235210281	617	8.043669635	531	0.97169498	-0.064669457	normal	0.923509897	0.25831675	normal	0.958023982	-0.167160936	normal	0.989067348	0.006429942	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Conserved mid region of cactin;; Cactus-binding C-terminus of cactin protein	Cactin GN=CACTIN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: cactin [Odobenus rosmarus divergens]
ENSG00000105321(CCDC9)	--	17.80688222	689	17.4539808	699	16.68360165	640	13.5322521	551	15.78859819	629	15.38236611	640	0.823686771	-0.35240301	normal	0.95823788	-0.173263605	normal	0.974446773	-0.008271896	normal	0.439649408	-0.176974165	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4594)	Coiled-coil domain-containing protein 9 GN=CCDC9 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 9 [Ceratotherium simum simum]
ENSG00000105323(HNRNPUL1)	--	154.5397511	11146	155.9738489	11497	159.643451	11595	183.1849056	13208	180.0870445	13141	173.8801187	12560	0.991635747	0.214026577	normal	0.993992664	0.171369955	normal	0.995900086	0.107028787	normal	0.465352649	0.163214529	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K15047|0|mcf:102126742|HNRNPUL1; heterogeneous nuclear ribonucleoprotein U-like 1; K15047 heterogeneous nuclear ribonucleoprotein U-like protein 1 (A)	Influenza A (ko05164)	[A]	RNA processing and modification	SPRY domain;; AAA domain;; SAP domain	Heterogeneous nuclear ribonucleoprotein U-like protein 1 GN=HNRNPUL1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein U-like 1 isoformX2 [Canis lupus familiaris]
ENSG00000105325(FZR1)	--	11.354924	877	9.165470674	734	10.57991114	821	11.10593501	793	11.47350632	868	9.880015036	784	0.96151592	-0.175764226	normal	0.94735774	0.220071073	normal	0.974748432	-0.074679226	normal	0.971889593	-0.013407283	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03364|0|nle:100586451|FZR1; fizzy/cell division cycle 20 related 1 (Drosophila); K03364 cell division cycle 20-like protein 1, cofactor of APC complex (A)"	Cell cycle (ko04110);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Fizzy-related protein homolog GN=FZR1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: fizzy-related protein homolog isoform X1 [Lipotes vexillifer]
ENSG00000105327(BBC3)	--	11.12147704	341	18.61440348	591	12.962458	415	13.090786	400	14.007347	430	32.484309	1007	0.94631501	0.198569294	normal	0.488496396	-0.478805098	normal	1.31E-10	1.267527524	up	0.693086714	0.428900993	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; Biological Process: positive regulation of apoptotic process (GO:0043065);; Biological Process: positive regulation of release of cytochrome c from mitochondria (GO:0090200);; Biological Process: intrinsic apoptotic signaling pathway (GO:0097193);; 	K10132|5.54003e-77|mcf:102119825|BBC3; BCL2 binding component 3; K10132 BCL2-binding component 3 (A)	p53 signaling pathway (ko04115);; Hippo signaling pathway (ko04390);; Huntington's disease (ko05016);; Measles (ko05162)	--	--	--	Bcl-2-binding component 3 GN=BBC3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bcl-2-binding component 3 [Galeopterus variegatus]
ENSG00000105329(TGFB1)	--	115.5664	5306	96.8511	4366	104.9722	4922	81.6278	3766	89.7096	4103	78.5741	3652	0.313766661	-0.525242415	normal	0.99010481	-0.111019857	normal	0.712788558	-0.438692252	normal	0.023108641	-0.362261429	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K13375|0|hsa:7040|TGFB1, CED, DPD1, LAP, TGFB, TGFbeta; transforming growth factor, beta 1; K13375 transforming growth factor beta-1 (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350);; Osteoclast differentiation (ko04380);; Hippo signaling pathway (ko04390);; Intestinal immune network for IgA production (ko04672);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Malaria (ko05144);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Chronic myeloid leukemia (ko05220);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Latency-associated peptide (Precursor) GN=TGFB1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	RecName: Full=Transforming growth factor beta-1; Short=TGF-beta-1; Contains: RecName: Full=Latency-associated peptide; Short=LAP; Flags: Precursor [Mustela putorius furo] 
ENSG00000105339(DENND3)	--	7.997349906	604	7.18236834	547	8.888229803	671	12.39563953	862	6.985823202	610	9.698545132	690	0.425094948	0.48127753	normal	0.963535168	0.135487021	normal	0.974740518	0.031921206	normal	0.411806356	0.225115988	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	"DENN (AEX-3) domain;; dDENN domain;; WD domain, G-beta repeat;; uDENN domain"	DENN domain-containing protein 3 GN=DENND3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 3 [Orcinus orca]
ENSG00000105341(ATP5SL)	--	63.36990747	1508	63.59839367	1526	59.35050539	1408	54.2929354	1295	59.66529881	1399	57.50021867	1386	0.946626558	-0.250241127	normal	0.97535858	-0.146633727	normal	0.983028762	-0.030977983	normal	0.485777474	-0.143733257	normal	--	--	--	--	--	[S]	Function unknown	--	ATP synthase subunit s-like protein GN=ATP5SL OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: ATP synthase subunit s-like protein [Pteropus alecto] 
ENSG00000105355(PLIN3)	--	52.75696397	2129	44.2136156	1707	54.84578517	2058	54.03048327	2285	50.37994834	2211	38.97605308	1720	0.986468117	0.071136395	normal	0.870549031	0.351535091	normal	0.946548071	-0.266911011	normal	0.867669608	0.054944171	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	Perilipin family	Perilipin-3 GN=PLIN3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: perilipin-3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000105357(MYH14)	--	1.418490433	172	2.26369	223	1.46792248	234	2.267022354	277	3.159835337	401	1.467715474	237	0.159476769	0.652016584	normal	0.004182195	0.820924268	normal	0.967039057	0.010022724	normal	0.227885087	0.519621918	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10352|0|pps:100987315|MYH14; myosin, heavy chain 14, non-muscle; K10352 myosin heavy chain (A)"	Tight junction (ko04530)	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail	Myosin-14 GN=MYH14 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: myosin-14 [Elephantulus edwardii]
ENSG00000105364(MRPL4)	--	32.38006566	741	30.45973445	722	31.73751967	757	35.83094788	832	40.23592798	910	35.60211041	816	0.968038217	0.136011486	normal	0.88660023	0.311858194	normal	0.972503885	0.099792356	normal	0.388276341	0.18333194	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02926|5.36498e-175|hsa:51073|MRPL4, CGI-28, L4mt; mitochondrial ribosomal protein L4; K02926 large subunit ribosomal protein L4 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L4/L1 family	"39S ribosomal protein L4, mitochondrial GN=MRPL4 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L4, mitochondrial [Galeopterus variegatus]"
ENSG00000105369(CD79A)	--	0.090239544	2	0.26495251	6	0.086725047	1	0.134355802	3	0.307561067	6	0.712727496	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06506|7.50649e-88|hsa:973|CD79A, IGA, MB-1; CD79a molecule, immunoglobulin-associated alpha; K06506 CD79A antigen (A)"	B cell receptor signaling pathway (ko04662);; Primary immunodeficiency (ko05340)	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	B-cell antigen receptor complex-associated protein alpha chain (Precursor) GN=CD79A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: B-cell antigen receptor complex-associated protein alpha chain isoform 1 [Equus caballus]
ENSG00000105371(ICAM4)	--	0.094405748	2	0	0	0	0	0	0	0	0	0.0463173	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06581|0|hsa:3386|ICAM4, CD242, LW; intercellular adhesion molecule 4 (Landsteiner-Wiener blood group); K06581 intercellular adhesion molecule 4 (A)"	--	--	--	"Intercellular adhesion molecule (ICAM), N-terminal domain"	Intercellular adhesion molecule 4 (Precursor) GN=ICAM4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: intercellular adhesion molecule 4 [Balaenoptera acutorostrata scammoni]
ENSG00000105372(RPS19)	--	3503.765337	27177	3531.771224	28354	3573.099149	29330	3451.261351	27805	3592.558706	28177	3541.903772	27793	0.998416611	0.002125745	normal	0.998327066	-0.030459187	normal	0.998175348	-0.085942392	normal	0.904901829	-0.039670793	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02966|1.66737e-102|tup:102483715|RPS19; ribosomal protein S19; K02966 small subunit ribosomal protein S19e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S19e	40S ribosomal protein S19 GN=RPS19 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S19 isoform X1 [Canis lupus familiaris]
ENSG00000105373(GLTSCR2)	--	177.431785	5114	155.2430138	4550	153.20175	4578	139.2727797	4027	159.16797	4587	163.284139	4739	0.882372432	-0.375451481	normal	0.992689971	-0.009738972	normal	0.992777447	0.041560262	normal	0.605720556	-0.113731739	normal	--	--	--	"K14840|0|hsa:29997|GLTSCR2, PICT-1, PICT1; glioma tumor suppressor candidate region gene 2; K14840 nucleolar protein 53 (A)"	Herpes simplex infection (ko05168)	[R]	General function prediction only	Nop53 (60S ribosomal biogenesis)	Glioma tumor suppressor candidate region gene 2 protein GN=GLTSCR2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: glioma tumor suppressor candidate region gene 2 protein isoform X4 [Mustela putorius furo] 
ENSG00000105374(NKG7)	--	0.220607	2	0.433858	4	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Protein NKG7 GN=NKG7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein NKG7 [Tupaia chinensis]
ENSG00000105376(ICAM5)	--	1.238572235	71	0.3952594	23	0.613727974	41	0.176523171	11	0.339623531	19	0.182165074	11	8.86E-08	-2.561192012	down	0.985134297	-0.276992549	normal	0.028410942	-1.772177211	normal	0.081982639	-1.740171591	normal	--	--	--	"K06769|0|hsa:7087|ICAM5, TLCN, TLN; intercellular adhesion molecule 5, telencephalin; K06769 intercellular adhesion molecule 5 (A)"	--	--	--	"Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Intercellular adhesion molecule (ICAM), N-terminal domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain"	Intercellular adhesion molecule 5 (Precursor) GN=ICAM5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: intercellular adhesion molecule 5 [Galeopterus variegatus]
ENSG00000105379(ETFB)	--	115.510582	1851	98.09405	1665	110.199605	1865	130.040711	2158	134.080322	2144	91.421791	1502	0.973405248	0.190411225	normal	0.881193339	0.343080923	normal	0.900091225	-0.320292261	normal	0.79609877	0.087161576	normal	[C]	Energy production and conversion	--	"K03521|0|hsa:2109|ETFB, MADD; electron-transfer-flavoprotein, beta polypeptide; K03521 electron transfer flavoprotein beta subunit (A)"	--	[C]	Energy production and conversion	Electron transfer flavoprotein domain	Electron transfer flavoprotein subunit beta GN=ETFB OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	"PREDICTED: LOW QUALITY PROTEIN: electron transfer flavoprotein subunit beta, partial [Camelus ferus]"
ENSG00000105383(CD33)	--	0	0	0	0	0	0	0.058391218	1	0.106314007	1	0.038679407	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06473|0|pps:100983058|CD33; CD33 molecule; K06473 CD33 antigen (A)	Hematopoietic cell lineage (ko04640)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain	Myeloid cell surface antigen CD33 (Precursor) GN=CD33 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: myeloid cell surface antigen CD33 [Camelus ferus]
ENSG00000105392(CRX)	--	0	0	0.012635148	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: multicellular organismal development (GO:0007275);; 	K09337|3.98975e-145|mcf:102129547|CRX; cone-rod homeobox; K09337 cone-rod homeobox protein (A)	--	[K]	Transcription	Homeobox domain;; Otx1 transcription factor	Cone-rod homeobox protein GN=CRX OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cone-rod homeobox protein [Galeopterus variegatus]
ENSG00000105393(BABAM1)	--	27.12211811	691	26.57578043	712	23.977151	614	29.33705402	761	28.19283333	740	29.09388488	758	0.970510526	0.108149289	normal	0.974784741	0.034150322	normal	0.898712856	0.295012645	normal	0.548391488	0.142024113	normal	--	--	--	--	--	--	--	--	BRISC and BRCA1-A complex member 1 GN=BABAM1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: BRISC and BRCA1-A complex member 1 [Camelus ferus] 
ENSG00000105397(TYK2)	--	12.15930555	965	16.8201492	972	11.66339109	1007	10.83198185	906	14.6327876	1060	16.171167	1183	0.972407384	-0.121650208	normal	0.974995595	0.103455324	normal	0.952327087	0.22378457	normal	0.764275791	0.076813685	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K11219|0|hsa:7297|TYK2, IMD35, JTK1; tyrosine kinase 2 (EC:2.7.10.2); K11219 non-receptor tyrosine-protein kinase TYK2 [EC:2.7.10.2] (A)"	Osteoclast differentiation (ko04380);; Jak-STAT signaling pathway (ko04630);; Toxoplasmosis (ko05145);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Non-receptor tyrosine-protein kinase TYK2 GN=TYK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: non-receptor tyrosine-protein kinase TYK2 [Ceratotherium simum simum]
ENSG00000105401(CDC37)	--	79.268951	2749	69.641002	2499	81.265465	2854	91.6897	3197	92.7396212	3176	72.90402275	2491	0.980122609	0.186882653	normal	0.922347663	0.32425903	normal	0.975496694	-0.204435707	normal	0.624077398	0.107992744	normal	--	--	Molecular Function: protein kinase binding (GO:0019901);; 	K09554|0|mcf:102144133|CDC37; cell division cycle 37; K09554 cell division cycle protein 37 (A)	PI3K-Akt signaling pathway (ko04151)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cdc37 Hsp90 binding domain;; Cdc37 N terminal kinase binding;; Cdc37 C terminal domain	"Hsp90 co-chaperone Cdc37, N-terminally processed GN=CDC37 OS=Homo sapiens (Human) PE=1 SV=1"	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: hsp90 co-chaperone Cdc37 [Tupaia chinensis] 
ENSG00000105402(NAPA)	--	42.41131725	1389	40.606197	1343	41.02173632	1411	48.93754302	1604	44.81018311	1455	58.11720806	1980	0.971145151	0.176613374	normal	0.979901432	0.094031548	normal	0.430145584	0.480054656	normal	0.234630632	0.261926392	normal	--	--	--	"K15296|0|ptr:456168|NAPA; N-ethylmaleimide-sensitive factor attachment protein, alpha; K15296 alpha-soluble NSF attachment protein (A)"	Synaptic vesicle cycle (ko04721)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Soluble NSF attachment protein, SNAP"	Alpha-soluble NSF attachment protein GN=NAPA OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: alpha-soluble NSF attachment protein [Camelus ferus] 
ENSG00000105404(RABAC1)	--	238.918961	2208	189.5703356	1851	213.823248	2081	251.2615269	2400	265.6823679	2464	219.787278	2072	0.986088388	0.089402292	normal	0.800842743	0.39099309	normal	0.987175981	-0.014533819	normal	0.430669099	0.154377865	normal	[UT]	"Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PRA1 family protein	Prenylated Rab acceptor protein 1 GN=RABAC1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: prenylated Rab acceptor protein 1 [Tupaia chinensis] 
ENSG00000105409(ATP1A3)	--	1.552348182	121	1.722465622	113	1.490086456	117	0.736212091	57	1.392812157	108	0.765711387	59	0.008669816	-1.096037798	down	0.966753584	-0.085546796	normal	0.045034531	-0.977871542	normal	0.079682355	-0.66872745	normal	--	--	--	"K01539|0|cjc:100410682|ATP1A3; ATPase, Na+/K+ transporting, alpha 3 polypeptide; K01539 sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Insulin secretion (ko04911);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Proximal tubule bicarbonate reclamation (ko04964);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Carbohydrate digestion and absorption (ko04973);; Protein digestion and absorption (ko04974);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Sodium/potassium-transporting ATPase subunit alpha-3 GN=ATP1A3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	Sodium/potassium-transporting ATPase subunit alpha-3 [Pteropus alecto]
ENSG00000105419(MEIS3)	--	33.00388816	1187	25.19402182	899	26.19854568	1011	21.98681496	818	28.83642011	1071	23.260451	862	0.119325544	-0.567089544	normal	0.947285671	0.230782848	normal	0.943079512	-0.237928793	normal	0.498949709	-0.191824771	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K16671|0|pps:100974088|MEIS3; Meis homeobox 3; K16671 homeobox protein Meis3 (A)	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein Meis3 GN=MEIS3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein Meis3 isoform X2 [Equus caballus]
ENSG00000105426(PTPRS)	--	40.1904058	5639	38.90620197	5688	36.95253221	5453	24.33339653	3482	28.77886883	4191	26.81726907	3850	0.002618029	-0.72610098	normal	0.661494619	-0.461909822	normal	0.390919711	-0.510313841	normal	0.000124261	-0.563119375	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K06778|0|hsa:5802|PTPRS, PTPSIGMA; protein tyrosine phosphatase, receptor type, S (EC:3.1.3.48); K06778 receptor-type tyrosine-protein phosphatase S [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Interferon-alpha/beta receptor, fibronectin type III;; Dual specificity phosphatase, catalytic domain;; Tissue factor;; Tyrosine phosphatase family;; Inositol hexakisphosphate;; CD80-like C2-set immunoglobulin domain"	Receptor-type tyrosine-protein phosphatase S (Precursor) GN=PTPRS OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase S [Odobenus rosmarus divergens]
ENSG00000105427(CNFN)	--	33.96510065	123	30.62450067	110	33.66750062	124	25.45570056	96	27.87210021	101	22.59470055	84	0.906345591	-0.382953837	normal	0.963771516	-0.142529069	normal	0.729093846	-0.561793133	normal	0.395358978	-0.366735832	normal	--	--	--	--	--	--	--	PLAC8 family	Cornifelin GN=CNFN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cornifelin isoform X1 [Galeopterus variegatus]
ENSG00000105429(MEGF8)	--	26.81854011	5797	22.81970257	5083	25.67481072	5679	27.69709853	5849	30.33158442	6504	30.64480497	6619	0.99415431	-0.017944025	normal	0.944445471	0.334132392	normal	0.985667685	0.212632421	normal	0.383404077	0.175569529	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; CUB domain;; Kelch motif;; Laminin EGF-like (Domains III and V);; Plexin repeat;; Calcium-binding EGF domain"	Multiple epidermal growth factor-like domains protein 8 (Precursor) GN=MEGF8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: multiple EGF-like-domains 8 [Canis lupus familiaris]
ENSG00000105438(KDELR1)	--	286.132027	5829	252.4316144	5132	272.0709849	5561	298.6327646	6212	300.5176357	6109	278.026743	5729	0.993887989	0.060961599	normal	0.982052992	0.229926348	normal	0.993864385	0.034638278	normal	0.642689264	0.106244803	normal	--	--	Biological Process: protein retention in ER lumen (GO:0006621);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ER retention sequence binding (GO:0046923);; 	K10949|7.08369e-95|tup:102480070|KDELR1; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1; K10949 ER lumen protein retaining receptor (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ER lumen protein retaining receptor;; ER lumen protein retaining receptor	ER lumen protein-retaining receptor 1 GN=KDELR1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ER lumen protein retaining receptor 1 [Tupaia chinensis]
ENSG00000105443(CYTH2)	--	76.82428714	4971	66.92420133	5090	70.36811272	5046	72.73520111	5219	75.43684042	5625	73.20661056	5290	0.993321472	0.039393152	normal	0.991273337	0.122726187	normal	0.993083966	0.059818563	normal	0.76701979	0.073777571	normal	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	K18441|0|mcc:718682|CYTH2; cytohesin 2; K18441 cytohesin (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; PH domain	Cytohesin-2 GN=CYTH2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: cytohesin-2 isoform X2 [Elephantulus edwardii]
ENSG00000105467(SYNGR4)	--	0.425086	6	0.901610877	10	0.477782196	6	0.211227	3	0.508110034	3	0.069717975	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Membrane-associating domain	Synaptogyrin-4 GN=SYNGR4 OS=Homo sapiens (Human) PE=2 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptogyrin-4 [Odobenus rosmarus divergens]
ENSG00000105472(CLEC11A)	--	4.8475739	113	4.44688889	109	4.336806266	107	4.254748488	101	5.195567549	120	5.24347474	124	0.96059015	-0.190064368	normal	0.964705048	0.115748794	normal	0.957420557	0.201786477	normal	0.949532857	0.047910012	normal	--	--	--	"K17521|5.38179e-176|pps:100993206|CLEC11A; C-type lectin domain family 11, member A; K17521 C-type lectin domain family 11 member A (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 11 member A (Precursor) GN=CLEC11A OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 11 member A [Canis lupus familiaris]
ENSG00000105479(CCDC114)	--	0.577802361	38	0.4637119	30	0.332684462	24	0.084474907	6	0.09618848	6	0.13996628	10	0.00105783	-2.418315362	down	0.043528639	-2.087347227	normal	0.883655164	-1.155518845	normal	0.000665253	-2.084313522	down	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 114 GN=CCDC114 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 114 [Galeopterus variegatus]
ENSG00000105483(CARD8)	--	13.38037856	561	13.76266147	650	10.50181514	686	13.03744439	632	11.07401733	528	11.69278511	668	0.963625527	0.140728266	normal	0.871938145	-0.320499318	normal	0.974193349	-0.046547923	normal	0.797421466	-0.074359004	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K12801|0|hsa:22900|CARD8, CARDINAL, DACAR, DAKAR, NDPP, NDPP1, TUCAN; caspase recruitment domain family, member 8; K12801 caspase recruitment domain-containing protein 8 (A)"	NOD-like receptor signaling pathway (ko04621)	--	--	Function to find;; Caspase recruitment domain	Caspase recruitment domain-containing protein 8 GN=CARD8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: caspase recruitment domain-containing protein 8-like [Tupaia chinensis]
ENSG00000105486(LIG1)	--	21.82484379	1801	22.97010897	1919	22.98746385	1942	19.20995793	1575	17.54898053	1421	16.31223512	1359	0.961549347	-0.224074003	normal	0.565581937	-0.454456812	normal	0.246588275	-0.52279985	normal	0.008689354	-0.400229459	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA ligase (ATP) activity (GO:0003910);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; 	"K10747|0|hsa:3978|LIG1; ligase I, DNA, ATP-dependent (EC:6.5.1.1); K10747 DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7] (A)"	DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430)	[L]	"Replication, recombination and repair"	ATP dependent DNA ligase domain;; DNA ligase N terminus;; ATP dependent DNA ligase C terminal region	DNA ligase 1 GN=LIG1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA ligase 1 isoform X1 [Galeopterus variegatus] 
ENSG00000105497(ZNF175)	--	2.122694241	186	3.841121497	233	3.373545194	236	1.637634365	174	1.845714092	182	3.066911603	225	0.961235135	-0.125971409	normal	0.850203161	-0.375056036	normal	0.964679887	-0.076650205	normal	0.596523919	-0.193209804	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7728|ZNF175, OTK18; zinc finger protein 175; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 175 GN=ZNF175 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 175 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000105499(PLA2G4C)	--	1.405022335	47	2.881013841	98	1.438814153	36	1.319953557	54	1.080464353	41	2.270943806	91	0.976158004	0.164448498	normal	0.005316734	-1.247877431	down	0.0055162	1.294225199	up	0.997630918	0.018438564	normal	--	--	Molecular Function: phospholipase activity (GO:0004620);; Biological Process: phospholipid catabolic process (GO:0009395);; 	"K16342|0|hsa:8605|PLA2G4C, CPLA2-gamma; phospholipase A2, group IVC (cytosolic, calcium-independent) (EC:3.1.1.4); K16342 cytosolic phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Platelet activation (ko04611);; Fc epsilon RI signaling pathway (ko04664);; Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Oxytocin signaling pathway (ko04921);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Lysophospholipase catalytic domain	Cytosolic phospholipase A2 gamma (Precursor) GN=PLA2G4C OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: cytosolic phospholipase A2 gamma isoform X3 [Tupaia chinensis]
ENSG00000105501(SIGLEC5)	--	0	0	0.0258413	1	0	0	0	0	0	0	0.025491152	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06549|0|hsa:8778|SIGLEC5, CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5; sialic acid binding Ig-like lectin 5; K06549 sialic acid binding Ig-like lectin 5/14 (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain	Sialic acid-binding Ig-like lectin 5 (Precursor) GN=SIGLEC5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: sialic acid-binding Ig-like lectin 5 [Loxodonta africana]
ENSG00000105509(HAS1)	--	0.493555	14	0.33427804	10	0.163346948	4	0.4491324	13	0.579042128	16	0.347466932	10	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K00752|0|hsa:3036|HAS1, HAS; hyaluronan synthase 1 (EC:2.4.1.212); K00752 hyaluronan synthase [EC:2.4.1.212] (A)"	--	[M]	Cell wall/membrane/envelope biogenesis	Glycosyltransferase like family 2;; Chitin synthase;; Glycosyl transferase family group 2;; Glycosyl transferase family 2;; Glycosyl transferase family 21	Hyaluronan synthase 1 GN=HAS1 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: hyaluronan synthase 1 [Mustela putorius furo]
ENSG00000105514(RAB3D)	--	144.3678661	2027	120.4081329	1714	116.9144816	1705	90.580013	1247	102.8029029	1328	87.31449991	1130	0.002154192	-0.731002889	normal	0.780052714	-0.389147276	normal	0.057443353	-0.601080778	normal	5.78E-05	-0.577268241	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07884|3.8208e-147|hsa:9545|RAB3D, D2-2, GOV, RAB16, RAD3D; RAB3D, member RAS oncogene family; K07884 Ras-related protein Rab-3D (A)"	Pancreatic secretion (ko04972)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-3D GN=RAB3D OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-3D [Ursus maritimus]
ENSG00000105516(DBP)	--	12.8677318	396	8.794717	304	8.936425961	280	3.709696514	112	4.992654772	143	6.323212148	191	9.99E-16	-1.838495417	down	3.17E-05	-1.101299646	down	0.402631445	-0.556483965	normal	0.000163804	-1.155652609	down	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09056|1.18666e-126|ptr:456185|DBP, CA11; D site of albumin promoter (albumin D-box) binding protein; K09056 albumin D box-binding protein (A)"	--	[K]	Transcription	Basic region leucine zipper	D site-binding protein GN=DBP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: D site-binding protein [Mustela putorius furo]
ENSG00000105519(CAPS)	--	2.950500001	167	1.868216208	120	1.9739071	127	1.672536	89	2.0001982	108	2.0920166	123	0.016249734	-0.926919906	normal	0.959910668	-0.171154741	normal	0.968160282	-0.053810489	normal	0.317788687	-0.391902971	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF-hand domain;; EF hand;; EF hand;; EF-hand domain pair	Calcyphosin GN=CAPS OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"Calcyphosin, partial [Myotis brandtii]"
ENSG00000105520(PLPPR2)	--	10.88963676	472	10.51663172	427	9.443041	419	9.269944444	385	10.495638	437	9.507444094	416	0.868564021	-0.323591963	normal	0.9695364	0.011928891	normal	0.970005474	-0.018590816	normal	0.713921503	-0.111352834	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	PAP2 superfamily	Lipid phosphate phosphatase-related protein type 2 GN=LPPR2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: lipid phosphate phosphatase-related protein type 2-like isoform X2 [Mustela putorius furo] 
ENSG00000105523(FAM83E)	--	0.4044342	12	0.210293	7	0.0873656	2	0	0	0.1534448	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF1669)	Protein FAM83E GN=FAM83E OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM83E [Galeopterus variegatus]
ENSG00000105538(RASIP1)	--	0.833968	33	0.368980494	10	0.457389304	18	0.371331725	15	0.259170562	9	0.317068	14	0.782817582	-1.09118355	normal	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[Z]	Cytoskeleton	DIL domain;; Ras association (RalGDS/AF-6) domain	Ras-interacting protein 1 GN=RASIP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras-interacting protein 1 [Odobenus rosmarus divergens]
ENSG00000105549(THEG)	--	0.34366475	9	0.119959085	3	0.110218375	4	0.04585394	2	0.071734305	2	0.090641907	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testicular haploid expressed repeat	Testicular haploid expressed gene protein GN=THEG OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: testicular haploid expressed gene protein isoform X1 [Sus scrofa]
ENSG00000105552(BCAT2)	--	41.37030504	1036	41.96933339	1143	39.66613678	1040	44.87419606	1171	40.31621027	1042	44.32719136	1212	0.971555679	0.145681511	normal	0.969693033	-0.154682239	normal	0.956958383	0.2122286	normal	0.789634621	0.068247915	normal	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K00826|0|pps:100995385|BCAT2; branched chain amino-acid transaminase 2, mitochondrial; K00826 branched-chain amino acid aminotransferase [EC:2.6.1.42] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Valine, leucine and isoleucine biosynthesis (ko00290);; Pantothenate and CoA biosynthesis (ko00770);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Aminotransferase class IV	"Branched-chain-amino-acid aminotransferase, mitochondrial (Precursor) GN=BCAT2 OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: branched-chain-amino-acid aminotransferase, mitochondrial [Orcinus orca] "
ENSG00000105556(MIER2)	--	5.30703057	358	5.682814058	377	6.054427354	408	5.067439786	317	5.118038	362	5.060362356	316	0.944120226	-0.205371583	normal	0.965342746	-0.07967519	normal	0.803604335	-0.375350702	normal	0.413954286	-0.221002699	normal	--	--	--	--	--	[R]	General function prediction only	ELM2 domain	Mesoderm induction early response protein 2 GN=MIER2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mesoderm induction early response protein 2 [Felis catus]
ENSG00000105559(PLEKHA4)	--	0.762662779	41	1.638632084	30	1.209798456	31	0.340845293	18	0.37041284	23	0.261148433	12	0.546049917	-1.151593556	normal	0.977551485	-0.382660872	normal	0.664257688	-1.27434775	normal	0.120712638	-0.966670984	normal	--	--	--	--	--	--	--	PH domain	Pleckstrin homology domain-containing family A member 4 GN=PLEKHA4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family A member 4 isoform 1 [Ceratotherium simum simum]
ENSG00000105568(PPP2R1A)	--	94.07878884	5530	95.62128791	5815	90.50065005	5480	110.346547	6519	110.072129	6533	98.15419415	5868	0.986247928	0.206486049	normal	0.991111738	0.14650393	normal	0.992933077	0.09037743	normal	0.486172081	0.147760284	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03456|0|ptr:468983|PPP2R1A; protein phosphatase 2, regulatory subunit A, alpha; K03456 serine/threonine-protein phosphatase 2A regulatory subunit A (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	HEAT repeat;; HEAT repeats;; Vacuolar 14 Fab1-binding region;; HEAT-like repeat;; Adaptin N terminal region;; CLASP N terminal	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform GN=PPP2R1A OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform-like [Myotis davidii]
ENSG00000105576(TNPO2)	--	17.75322816	1625	17.81437312	1674	19.10031758	1655	18.91019944	1698	21.07027905	1803	19.25475545	1527	0.984781553	0.032534385	normal	0.982988257	0.08559879	normal	0.979421446	-0.124304311	normal	1	-4.93E-05	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	K18727|0|ssc:100519078|TNPO2; transportin 2; K18727 transportin-2 (A)	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	HEAT repeat;; HEAT-like repeat;; HEAT repeats;; Armadillo/beta-catenin-like repeat;; Vacuolar 14 Fab1-binding region;; non-SMC mitotic condensation complex subunit 1;; Importin-beta N-terminal domain;; Adaptin N terminal region;; Myosin-binding striated muscle assembly central;; Proteasome non-ATPase 26S subunit	Transportin-2 GN=TNPO2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transportin-2 isoform X1 [Sus scrofa] 
ENSG00000105605(CACNG7)	--	27.23649296	1251	20.36226879	879	22.23218	973	2.681119268	105	4.6386882	211	1.7606257	81	0	-3.586024245	down	0	-2.072128786	down	0	-3.570208504	down	1.78E-18	-2.987831407	down	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K04872|0|tup:102482749|CACNG7; calcium channel, voltage-dependent, gamma subunit 7; K04872 voltage-dependent calcium channel gamma-7 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Voltage-dependent calcium channel gamma-7 subunit GN=CACNG7 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: voltage-dependent calcium channel gamma-7 subunit isoform X1 [Galeopterus variegatus]
ENSG00000105607(GCDH)	--	6.771781697	125	2.952911842	113	3.66296964	138	6.093126444	189	5.813987583	153	5.222454002	146	0.564235097	0.559993112	normal	0.864099683	0.411038932	normal	0.966539691	0.072238938	normal	0.340888065	0.354403012	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00252|0|hsa:2639|GCDH, ACAD5, GCD; glutaryl-CoA dehydrogenase (EC:1.3.8.6); K00252 glutaryl-CoA dehydrogenase [EC:1.3.8.6] (A)"	Fatty acid degradation (ko00071);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380)	[E]	Amino acid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	"Glutaryl-CoA dehydrogenase, mitochondrial (Precursor) GN=GCDH OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: glutaryl-CoA dehydrogenase, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000105610(KLF1)	--	0.0415764	1	0	0	0.0390133	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09204|0|hsa:10661|KLF1, CDAN4, EKLF, HBFQTL6, INLU; Kruppel-like factor 1 (erythroid); K09204 krueppel-like factor 1 (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 1 GN=KLF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: Krueppel-like factor 1 [Galeopterus variegatus]
ENSG00000105612(DNASE2)	--	40.26881122	1091	45.986065	1263	35.791879	1015	26.72632733	730	27.06410873	696	37.25240323	1012	0.054624409	-0.609457944	normal	6.26E-05	-0.879681035	normal	0.979714368	-0.012543163	normal	0.047899051	-0.487144356	normal	--	--	Molecular Function: deoxyribonuclease II activity (GO:0004531);; Biological Process: DNA metabolic process (GO:0006259);; 	"K01158|0|hsa:1777|DNASE2, DNASE2A, DNL, DNL2; deoxyribonuclease II, lysosomal (EC:3.1.22.1); K01158 deoxyribonuclease II [EC:3.1.22.1] (A)"	Lysosome (ko04142)	[L]	"Replication, recombination and repair"	Deoxyribonuclease II	Deoxyribonuclease-2-alpha (Precursor) GN=DNASE2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: deoxyribonuclease-2-alpha isoform X2 [Galeopterus variegatus]
ENSG00000105613(MAST1)	--	2.323267	114	1.4009085	79	1.679139447	90	1.122037377	55	1.640616591	77	1.041533412	51	0.018610907	-1.061302839	normal	0.971613689	-0.057309496	normal	0.424144773	-0.809413958	normal	0.129316495	-0.650192958	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08789|0|hsa:22983|MAST1, SAST, SAST170; microtubule associated serine/threonine kinase 1 (EC:2.7.11.1); K08789 microtubule-associated serine/threonine kinase [EC:2.7.11.1] (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	Domain of unknown function (DUF1908);; Protein kinase domain;; Protein tyrosine kinase;; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Microtubule-associated serine/threonine-protein kinase 1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: microtubule-associated serine/threonine-protein kinase 1 isoform X1 [Mustela putorius furo]
ENSG00000105617(LENG1)	--	7.48701	249	6.65378	228	7.76207	269	5.90365	199	6.38536	211	5.95297	200	0.868511771	-0.351775596	normal	0.958374158	-0.132304863	normal	0.747760773	-0.433063467	normal	0.304462578	-0.311270534	normal	--	--	--	--	--	--	--	--	Leukocyte receptor cluster member 1 GN=LENG1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leukocyte receptor cluster member 1 [Equus caballus]
ENSG00000105618(PRPF31)	--	56.52333437	2222	54.69174735	2229	54.72074394	2205	58.34309243	2340	56.75175663	2246	55.53053599	2237	0.98758232	0.043787945	normal	0.987527532	-0.010458178	normal	0.987785019	0.012486656	normal	0.965425694	0.01440133	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K12844|0|ptr:456278|PRPF31; pre-mRNA processing factor 31; K12844 U4/U6 small nuclear ribonucleoprotein PRP31 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	Putative snoRNA binding domain;; Prp31 C terminal domain;; NOSIC (NUC001) domain	U4/U6 small nuclear ribonucleoprotein Prp31 GN=PRPF31 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PRP31 pre-mRNA processing factor 31 homolog (predicted) [Dasypus novemcinctus]
ENSG00000105619(TFPT)	--	9.53197	224	8.062530002	198	8.201908	201	7.645378	157	9.37416	219	9.30425	221	0.538328301	-0.539123802	normal	0.95958504	0.123109564	normal	0.960300522	0.127643252	normal	0.857218556	-0.081688374	normal	--	--	--	K11670|1.15846e-117|pps:100981733|TFPT; TCF3 (E2A) fusion partner (in childhood Leukemia); K11670 TCF3 fusion partner (A)	--	--	--	--	TCF3 fusion partner GN=TFPT OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TCF3 fusion partner [Orcinus orca] 
ENSG00000105639(JAK3)	--	1.89605268	124	0.978211142	90	0.97842711	87	0.51081551	30	1.189371921	53	0.64802253	38	6.62E-09	-2.022905836	down	0.502750623	-0.768336313	normal	0.025820956	-1.171638299	normal	0.000511264	-1.335386325	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K11218|0|hsa:3718|JAK3, JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK; Janus kinase 3 (EC:2.7.10.2); K11218 Janus kinase 3 [EC:2.7.10.2] (A)"	Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; Measles (ko05162);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203);; Primary immunodeficiency (ko05340)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Tyrosine-protein kinase JAK3 GN=JAK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase JAK3 [Galeopterus variegatus]
ENSG00000105640(RPL18A)	--	1221.597159	9720	1164.2061	9521	1143.524284	9588	1106.157496	9430	1159.825111	9212	1076.16904	8883	0.995657551	-0.074518847	normal	0.995471261	-0.069014111	normal	0.994603292	-0.118454944	normal	0.728326811	-0.088143672	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02882|2.50039e-129|ptr:748555|RPL18A; ribosomal protein L18a; K02882 large subunit ribosomal protein L18Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L18ae/LX protein domain	60S ribosomal protein L18a GN=RPL18A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L18a [Loxodonta africana] 
ENSG00000105641(SLC5A5)	--	0.0662808	4	0.0650657	4	0.0159412	0	0	0	0.0483438	2	0.0163772	1	--	--	--	--	--	--	--	--	--	--	--	--	[ER]	Amino acid transport and metabolism;; General function prediction only	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14385|0|hsa:6528|SLC5A5, NIS, TDH1; solute carrier family 5 (sodium/iodide cotransporter), member 5; K14385 solute carrier family 5 (sodium/iodide cotransporter), member 5 (A)"	Thyroid hormone synthesis (ko04918)	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium/iodide cotransporter GN=SLC5A5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/iodide cotransporter [Galeopterus variegatus]
ENSG00000105642(KCNN1)	--	2.681415248	62	0.582157166	25	0.762180348	40	0.268794318	20	2.620122867	39	0.120962881	9	0.004570344	-1.590162753	down	0.947624447	0.591282858	normal	0.009099992	-1.989005814	down	0.348218967	-0.923316114	normal	--	--	Molecular Function: calmodulin binding (GO:0005516);; Biological Process: potassium ion transport (GO:0006813);; Molecular Function: calcium-activated potassium channel activity (GO:0015269);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: small conductance calcium-activated potassium channel activity (GO:0016286);; 	"K04942|0|ptr:468768|KCNN1; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1; K04942 potassium intermediate/small conductance calcium-activated channel subfamily N member 1 (A)"	Insulin secretion (ko04911)	[P]	Inorganic ion transport and metabolism	Calcium-activated SK potassium channel;; Calmodulin binding domain;; Ion channel	Small conductance calcium-activated potassium channel protein 1 GN=KCNN1 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: small conductance calcium-activated potassium channel protein 1 [Condylura cristata]
ENSG00000105643(ARRDC2)	--	7.39337	395	8.366741993	474	6.316590464	369	6.446236	356	8.091081074	437	7.216325085	412	0.95133893	-0.180069431	normal	0.960442834	-0.138220893	normal	0.95801631	0.150149452	normal	0.867131421	-0.059995348	normal	--	--	--	--	--	[R]	General function prediction only	"Arrestin (or S-antigen), N-terminal domain;; Arrestin (or S-antigen), C-terminal domain"	Arrestin domain-containing protein 2 GN=ARRDC2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: arrestin domain-containing protein 2 isoform X1 [Leptonychotes weddellii]
ENSG00000105647(PIK3R2)	--	13.33539471	1075	11.43326	921	13.45852138	1088	15.52572763	1256	17.4317275	1405	15.21645021	1241	0.962941531	0.193411617	normal	0.091837177	0.587084645	normal	0.965980096	0.18129701	normal	0.05657008	0.318439223	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K02649|0|ptr:455855|PIK3R2; phosphoinositide-3-kinase, regulatory subunit 2 (beta); K02649 phosphoinositide-3-kinase, regulatory subunit (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; Carbohydrate digestion and absorption (ko04973);; Bacterial invasion of epithelial cells (ko05100);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	SH2 domain;; RhoGAP domain	Phosphatidylinositol 3-kinase regulatory subunit beta GN=PIK3R2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 3-kinase regulatory subunit beta [Canis lupus familiaris]
ENSG00000105649(RAB3A)	--	1.157794745	31	0.41489053	11	1.730842163	42	1.0116149	20	1.120181946	30	0.587909578	16	0.96133268	-0.624280445	normal	0.655466507	1.31295162	normal	0.292019728	-1.320844652	normal	0.755789473	-0.367899079	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07882|2.20226e-164|ptr:455857|RAB3A; RAB3A, member RAS oncogene family; K07882 Ras-related protein Rab-3A (A)"	Synaptic vesicle cycle (ko04721);; Insulin secretion (ko04911)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-3A GN=RAB3A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	ras-related protein Rab-3A [Bos taurus] 
ENSG00000105650(PDE4C)	--	0.178610685	19	0.159528418	13	0.205288803	22	0.425907211	10	0.26356321	17	0.203849001	18	--	--	--	--	--	--	0.986585648	-0.276735465	normal	--	--	--	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13293|0|hsa:5143|PDE4C, DPDE1; phosphodiesterase 4C, cAMP-specific (EC:3.1.4.53); K13293 cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; cAMP signaling pathway (ko04024);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase	"cAMP-specific 3',5'-cyclic phosphodiesterase 4C GN=PDE4C OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: cAMP-specific 3',5'-cyclic phosphodiesterase 4C [Leptonychotes weddellii]"
ENSG00000105655(ISYNA1)	--	62.34387997	1694	52.351435	1346	52.496171	1380	19.504674	526	25.4523752	720	17.589864	473	0	-1.715172454	down	1.53E-05	-0.922594637	normal	1.11E-16	-1.550004732	down	4.95E-11	-1.38387297	down	[I]	Lipid transport and metabolism	Molecular Function: inositol-3-phosphate synthase activity (GO:0004512);; Biological Process: inositol biosynthetic process (GO:0006021);; Biological Process: phospholipid biosynthetic process (GO:0008654);; 	K01858|0|ptr:455861|ISYNA1; inositol-3-phosphate synthase 1 (EC:5.5.1.4); K01858 myo-inositol-1-phosphate synthase [EC:5.5.1.4] (A)	Inositol phosphate metabolism (ko00562)	[I]	Lipid transport and metabolism	Myo-inositol-1-phosphate synthase;; Myo-inositol-1-phosphate synthase	Inositol-3-phosphate synthase 1 GN=ISYNA1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: inositol-3-phosphate synthase 1 [Condylura cristata]
ENSG00000105656(ELL)	--	3.219868384	255	3.482336982	263	3.261582448	239	2.792671417	220	3.299474763	260	3.02444052	228	0.934209288	-0.242252731	normal	0.965652366	-0.037759363	normal	0.96474127	-0.075777265	normal	0.757636783	-0.117697514	normal	--	--	Biological Process: transcription elongation from RNA polymerase II promoter (GO:0006368);; Cellular Component: transcription elongation factor complex (GO:0008023);; 	"K15183|0|hsa:8178|ELL, C19orf17, ELL1, MEN, PPP1R68; elongation factor RNA polymerase II; K15183 RNA polymerase II elongation factor ELL (A)"	--	[K]	Transcription	RNA polymerase II elongation factor ELL;; Occludin homology domain	RNA polymerase II elongation factor ELL GN=ELL OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: RNA polymerase II elongation factor ELL [Felis catus]
ENSG00000105662(CRTC1)	--	5.685083	544	7.15531567	699	5.846609725	567	5.288955764	497	7.685785668	728	8.719726843	791	0.958355019	-0.160717932	normal	0.974487031	0.0371407	normal	0.473465069	0.470969269	normal	0.771785816	0.135504137	normal	--	--	Molecular Function: cAMP response element binding protein binding (GO:0008140);; Biological Process: protein homotetramerization (GO:0051289);; 	"K15309|0|hsa:23373|CRTC1, MECT1, TORC-1, TORC1, WAMTP1; CREB regulated transcription coactivator 1; K15309 CREB-regulated transcription coactivator 1 (A)"	HTLV-I infection (ko05166)	--	--	"Transducer of regulated CREB activity middle domain;; Transducer of regulated CREB activity, C terminus;; Transducer of regulated CREB activity, N terminus"	CREB-regulated transcription coactivator 1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CREB-regulated transcription coactivator 1 isoformX2 [Canis lupus familiaris] 
ENSG00000105668(UPK1A)	--	4.763183498	79	3.533533519	55	4.380036623	76	1.22948	23	0.802878529	14	0.845301385	16	0.000106711	-1.744287261	down	0.001078181	-1.885248766	down	2.26E-06	-2.153910008	down	1.01E-05	-2.008573818	down	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17347|3.89693e-167|hsa:11045|UPK1A, TSPAN21, UP1A, UPIA, UPKA; uroplakin 1A; K17347 uroplakin 1 (A)"	--	[R]	General function prediction only	Tetraspanin family;; Putative binding domain	Uroplakin-1a GN=UPK1A OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: uroplakin-1a isoform X2 [Myotis brandtii] 
ENSG00000105669(COPE)	--	66.31522334	1369	60.4864017	1283	60.3815421	1300	65.33177038	1378	66.494013	1370	70.186843	1463	0.982966514	-0.021354934	normal	0.980515136	0.073144724	normal	0.972550103	0.161949021	normal	0.777303073	0.070540855	normal	--	--	--	"K17268|0|hsa:11316|COPE, epsilon-COP; coatomer protein complex, subunit epsilon; K17268 coatomer protein complex, subunit epsilon (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Coatomer epsilon subunit;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Coatomer subunit epsilon GN=COPE OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit epsilon [Tupaia chinensis]
ENSG00000105671(DDX49)	--	12.309734	465	13.138021	503	14.28740397	553	12.873414	491	12.623079	476	14.186255	542	0.970275998	0.047507283	normal	0.96603978	-0.100712065	normal	0.972171324	-0.037175379	normal	0.928879086	-0.032114366	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K14778|0|ptr:455866|DDX49; DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 (EC:3.6.4.13); K14778 ATP-dependent RNA helicase DDX49/DBP8 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX49 GN=DDX49 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX49 [Sus scrofa]
ENSG00000105672(ETV2)	--	2.208459322	22	4.528868764	36	0.990134735	23	1.608183119	17	0.879939953	19	1.236686917	19	0.985360294	-0.37307962	normal	0.86436532	-0.891079752	normal	0.986184898	-0.264746758	normal	0.447482345	-0.579820858	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09432|0|mcf:102143096|ETV2; ets variant 2; K09432 ETS translocation variant 2 (A)	--	[K]	Transcription	Ets-domain	ETS translocation variant 2 GN=ETV2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: ETS translocation variant 2 isoform X1 [Galeopterus variegatus]
ENSG00000105675(ATP4A)	--	0.0134752	1	0	0	0.0130199	0	0	0	0.0130914	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrogen:potassium-exchanging ATPase activity (GO:0008900);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: membrane (GO:0016020);; 	"K01542|0|hsa:495|ATP4A, ATP6A; ATPase, H+/K+ exchanging, alpha polypeptide (EC:3.6.3.10); K01542 H+/K+-exchanging ATPase alpha polypeptide [EC:3.6.3.10] (A)"	Oxidative phosphorylation (ko00190);; Collecting duct acid secretion (ko04966);; Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Gastric H+/K+-ATPase, N terminal domain;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase"	Potassium-transporting ATPase alpha chain 1 GN=ATP4A OS=Homo sapiens (Human) PE=2 SV=5	P	Inorganic ion transport and metabolism	potassium-transporting ATPase alpha chain 1 [Oryctolagus cuniculus] 
ENSG00000105676(ARMC6)	--	12.83751995	580	13.7163952	586	13.07402606	624	12.61921344	560	14.32487353	596	11.84736402	546	0.970100352	-0.0812393	normal	0.972869752	0.002977489	normal	0.949674354	-0.20041685	normal	0.737561593	-0.093829931	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Armadillo/beta-catenin-like repeat	Armadillo repeat-containing protein 6 GN=ARMC6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: armadillo repeat containing 6 isoform X1 [Sus scrofa]
ENSG00000105677(TMEM147)	--	208.5579012	2378	204.9684217	2412	197.0056037	2325	211.766473	2467	205.3525328	2342	217.300481	2496	0.988445175	0.022162679	normal	0.987105188	-0.063874744	normal	0.986306512	0.094036732	normal	0.958484282	0.016787996	normal	--	--	--	--	--	[S]	Function unknown	Predicted membrane protein (DUF2053)	Transmembrane protein 147 GN=TMEM147 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 147 isoform X1 [Orycteropus afer afer]
ENSG00000105679(GAPDHS)	--	0.264592	7	0.0373345	1	0.146979	3	0.0375969	1	0.0366884	0	0.0747932	2	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K10705|0|hsa:26330|GAPDHS, GAPD2, GAPDH-2, GAPDS, HSD-35; glyceraldehyde-3-phosphate dehydrogenase, spermatogenic (EC:1.2.1.12); K10705 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic [EC:1.2.1.12] (A)"	Glycolysis / Gluconeogenesis (ko00010)	[G]	Carbohydrate transport and metabolism	"Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain;; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain"	"Glyceraldehyde-3-phosphate dehydrogenase, testis-specific GN=GAPDHS OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: glyceraldehyde-3-phosphate dehydrogenase, testis-specific [Tupaia chinensis]"
ENSG00000105696(TMEM59L)	--	5.561810166	158	4.32659008	96	4.382615202	126	3.78069	106	6.305202536	176	3.268657105	92	0.536990501	-0.599523749	normal	0.0478254	0.843093809	normal	0.855106885	-0.45558365	normal	0.967377887	-0.044092841	normal	--	--	--	--	--	--	--	Brain specific membrane anchored protein	Transmembrane protein 59-like (Precursor) GN=TMEM59L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 59-like [Galeopterus variegatus]
ENSG00000105698(USF2)	--	67.90357527	2049	69.080376	2133	68.47542783	2111	73.557466	2237	75.18551139	2320	91.54787625	2850	0.985017438	0.095744287	normal	0.984877715	0.09974646	normal	0.701078691	0.424481241	normal	0.247815697	0.214678876	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09106|0|hsa:7392|USF2, FIP, bHLHb12; upstream transcription factor 2, c-fos interacting; K09106 upstream stimulatory factor (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Upstream stimulatory factor 2 GN=USF2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: upstream stimulatory factor 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000105699(LSR)	--	1.331610704	48	1.519242946	49	1.407245999	45	2.95295673	107	6.630351317	159	3.124318397	112	0.019026317	1.10148094	normal	1.96E-07	1.646972557	up	0.001499901	1.279063243	up	7.13E-05	1.391490719	up	--	--	--	--	--	--	--	Lipolysis stimulated receptor (LSR);; Immunoglobulin domain	Lipolysis-stimulated lipoprotein receptor GN=LSR OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	hypothetical protein PANDA_009746 [Ailuropoda melanoleuca]
ENSG00000105700(KXD1)	--	50.55488011	1351	45.55377734	1188	50.57024543	1393	52.92812528	1436	53.60744943	1472	44.19504181	1196	0.982197487	0.057132786	normal	0.923385723	0.287486973	normal	0.954391453	-0.228001898	normal	0.884613309	0.040298204	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein	KxDL motif-containing protein 1 GN=KXD1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: kxDL motif-containing protein 1 [Ceratotherium simum simum]
ENSG00000105701(FKBP8)	--	85.03009031	2969	82.66343838	2940	82.18734299	2980	70.10574748	2461	77.86296015	2710	70.94937119	2462	0.937044274	-0.301393081	normal	0.984693324	-0.13887543	normal	0.94850551	-0.283614409	normal	0.16380379	-0.240888239	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K09574|0|ptr:455862|FKBP8; FK506 binding protein 8, 38kDa; K09574 FK506-binding protein 8 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TPR repeat;; FKBP-type peptidyl-prolyl cis-trans isomerase;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Fis1 C-terminal tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Peptidyl-prolyl cis-trans isomerase FKBP8 GN=FKBP8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP8 isoform X1 [Eptesicus fuscus]
ENSG00000105705(SUGP1)	--	7.649162039	362	7.52785	340	6.207660372	338	7.502104007	393	8.952735	445	7.168473579	374	0.965702904	0.087351484	normal	0.817498311	0.365419554	normal	0.959612252	0.137140047	normal	0.468029786	0.199499873	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; 	"K13096|0|hsa:57794|SUGP1, F23858, RBP, SF4; SURP and G patch domain containing 1; K13096 splicing factor 4 (A)"	--	[R]	General function prediction only	Surp module;; G-patch domain;; DExH-box splicing factor binding site	SURP and G-patch domain-containing protein 1 GN=SUGP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: SURP and G-patch domain-containing protein 1 [Galeopterus variegatus]
ENSG00000105707(HPN)	--	0.033875615	1	0	0	0.0698745	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; Molecular Function: serine-type exopeptidase activity (GO:0070008);; 	K08665|0|ptr:455944|HPN; hepsin; K08665 hepsin [EC:3.4.21.106] (A)	Viral carcinogenesis (ko05203)	[E]	Amino acid transport and metabolism	"Trypsin;; Hepsin, SRCR;; Scavenger receptor cysteine-rich domain"	Serine protease hepsin catalytic chain GN=HPN OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	GRAM domain-containing protein 1A [Tupaia chinensis]
ENSG00000105708(ZNF14)	--	1.64844	96	1.73178	100	1.48084	85	1.34821	79	1.13224	66	1.82079	107	0.947159692	-0.306594825	normal	0.733116612	-0.609459336	normal	0.939711358	0.318720257	normal	0.758568976	-0.177730007	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7561|ZNF14, GIOT-4, KOX6; zinc finger protein 14; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Probable zinc-binding domain"	Zinc finger protein 14 GN=ZNF14 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 709 [Galeopterus variegatus]
ENSG00000105711(SCN1B)	--	13.56139641	386	9.573678389	284	13.35399173	362	16.42069377	467	16.37457285	467	14.89704274	432	0.929766097	0.243108666	normal	0.033848752	0.693198812	normal	0.928650602	0.245809021	normal	0.080872761	0.383316899	normal	--	--	--	"K04845|1.20501e-93|myb:102262662|SCN1B; sodium channel, voltage-gated, type I, beta subunit; K04845 voltage-gated sodium channel type I beta (A)"	Adrenergic signaling in cardiomyocytes (ko04261)	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain	Sodium channel subunit beta-1 (Precursor) GN=SCN1B OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel subunit beta-1 [Myotis brandtii]
ENSG00000105717(PBX4)	--	1.688742405	45	1.67388551	47	1.559976549	43	1.390459135	40	1.75786659	44	0.656083809	18	0.977910169	-0.193736208	normal	0.977682903	-0.112830728	normal	0.43514156	-1.197649988	normal	0.525197722	-0.427462058	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K15611|0|hsa:80714|PBX4; pre-B-cell leukemia homeobox 4; K15611 pre-B-cell leukemia transcription factor 4 (A)	--	[K]	Transcription	PBC domain;; Homeobox domain;; Homeobox KN domain	Pre-B-cell leukemia transcription factor 4 GN=PBX4 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: pre-B-cell leukemia transcription factor 4 [Odobenus rosmarus divergens]
ENSG00000105722(ERF)	--	147.809734	6574	141.112966	6629	141.470085	6658	132.713789	5659	136.256858	6043	123.63825	5621	0.980159644	-0.24699429	normal	0.990841578	-0.154915837	normal	0.978973135	-0.252491001	normal	0.246358309	-0.218405879	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09434|0|mmu:13875|Erf; Ets2 repressor factor; K09434 ETS domain-containing transcription factor ERF (A)	--	[K]	Transcription	Ets-domain	ETS domain-containing transcription factor ERF GN=ERF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS domain-containing transcription factor ERF [Ceratotherium simum simum]
ENSG00000105726(ATP13A1)	--	12.0185901	949	13.10327973	1047	12.28849981	986	14.51106958	1143	15.04623902	1162	16.68422753	1325	0.945590234	0.237162895	normal	0.973504972	0.128745496	normal	0.669378089	0.417487067	normal	0.139291545	0.262892337	normal	[P]	Inorganic ion transport and metabolism	--	"K14950|0|hsa:57130|ATP13A1, ATP13A; ATPase type 13A1 (EC:3.6.3.8); K14950 cation-transporting ATPase 13A1 [EC:3.6.3.-] (A)"	--	[P]	Inorganic ion transport and metabolism	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Manganese-transporting ATPase 13A1 GN=ATP13A1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: probable cation-transporting ATPase 13A1 [Leptonychotes weddellii]
ENSG00000105732(ZNF574)	--	18.102992	1019	18.866745	1070	17.86553841	1036	16.1670233	900	16.385215	910	17.8303561	1010	0.954504076	-0.20965276	normal	0.936116732	-0.254708048	normal	0.979133819	-0.044893778	normal	0.410104153	-0.169036778	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 574 GN=ZNF574 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 574 isoform X1 [Myotis davidii]
ENSG00000105737(GRIK5)	--	0.656074679	36	0.379314832	24	0.338366485	20	0.288998223	18	0.357974	21	0.491125524	29	0.825701249	-0.971112068	normal	0.98557341	-0.200551477	normal	0.974527503	0.496434866	normal	0.789102388	-0.254799133	normal	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05205|0|hsa:2901|GRIK5, EAA2, GRIK2, GluK5, KA2; glutamate receptor, ionotropic, kainate 5; K05205 glutamate receptor, ionotropic kainate 5 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Receptor family ligand binding region;; Ligand-gated ion channel;; Ligated ion channel L-glutamate- and glycine-binding site;; Bacterial extracellular solute-binding proteins, family 3"	"Glutamate receptor ionotropic, kainate 5 (Precursor) GN=GRIK5 OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, kainate 5 [Equus przewalskii]"
ENSG00000105738(SIPA1L3)	--	33.1129705	5597	32.03488062	5401	35.44047845	6193	29.45471563	4981	28.73288777	4936	30.884828	5298	0.985740279	-0.198992651	normal	0.989510338	-0.151266388	normal	0.981728413	-0.233420351	normal	0.304373863	-0.196948765	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	"K17703|0|hsa:23094|SIPA1L3, SPAL3; signal-induced proliferation-associated 1 like 3; K17703 signal-induced proliferation-associated 1 like protein 3 (A)"	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3401);; Rap/ran-GAP	Signal-induced proliferation-associated 1-like protein 3 GN=SIPA1L3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: signal-induced proliferation-associated 1-like protein 3 isoform X1 [Oryctolagus cuniculus] 
ENSG00000105750(ZNF85)	--	0.221788421	3	0	0	0.119910177	4	0.413759053	4	0.065460853	1	0.42878292	10	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7639|ZNF85, HPF4, HTF1; zinc finger protein 85; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; SprT-like family;; C1-like domain;; GAGA factor"	Zinc finger protein 85 GN=ZNF85 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	TPA: repressor transcriptional factor-like [Bos taurus]
ENSG00000105755(ETHE1)	--	29.38920243	394	19.689165	270	24.674459	342	48.291222	656	49.152584	655	33.31700381	451	0.013647305	0.702523819	normal	4.80E-09	1.252462307	up	0.771247671	0.389335925	normal	0.007042687	0.786549227	normal	[R]	General function prediction only	--	"K17725|4.78761e-173|hsa:23474|ETHE1, HSCO, YF13H12; ethylmalonic encephalopathy 1 (EC:1.13.11.18); K17725 sulfur dioxygenase [EC:1.13.11.18] (A)"	Sulfur metabolism (ko00920)	[R]	General function prediction only	Metallo-beta-lactamase superfamily	"Persulfide dioxygenase ETHE1, mitochondrial (Precursor) GN=ETHE1 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: protein ETHE1, mitochondrial isoform 1 [Trichechus manatus latirostris]"
ENSG00000105767(CADM4)	--	12.26	522	9.25704	411	10.5458	466	8.23773	355	12.3048	518	9.1772	393	0.15143053	-0.58496096	normal	0.88184441	0.311364679	normal	0.924931754	-0.253196188	normal	0.629099757	-0.164810181	normal	--	--	--	"K06783|0|hsa:199731|CADM4, IGSF4C, NECL4, Necl-4, TSLL2, synCAM4; cell adhesion molecule 4; K06783 cell adhesion molecule 4 (A)"	--	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain	Cell adhesion molecule 4 (Precursor) GN=CADM4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cell adhesion molecule 4 [Lipotes vexillifer]
ENSG00000105771(SMG9)	--	14.48696165	826	14.97636811	850	15.65770877	867	16.4825193	908	14.82928784	825	21.32403796	1184	0.973107905	0.105530992	normal	0.975300421	-0.06437901	normal	0.581033132	0.440613515	normal	0.557156575	0.177578642	normal	--	--	"Biological Process: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184);; "	K18735|0|ptr:456097|SMG9; SMG9 nonsense mediated mRNA decay factor; K18735 protein SMG9 (A)	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2146)	Protein SMG9 GN=SMG9 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: protein SMG9 isoform X2 [Tupaia chinensis]
ENSG00000105778(AVL9)	--	14.71044022	1628	15.525648	1726	14.47383976	1585	12.43602672	1260	13.6029789	1465	15.89610939	1761	0.735093812	-0.400078677	normal	0.947078005	-0.257712945	normal	0.977999204	0.143490687	normal	0.503383858	-0.159078179	normal	--	--	--	--	--	[S]	Function unknown	Transport protein Avl9;; Uncharacterized conserved protein (DUF2347);; Stabilization of polarity axis;; Docking domain of Afi1 for Arf3 in vesicle trafficking	Late secretory pathway protein AVL9 homolog GN=AVL9 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: late secretory pathway protein AVL9 homolog isoform 1 [Dasypus novemcinctus]
ENSG00000105784(RUNDC3B)	--	0.08476972	4	0.0558575	2	0.195326	6	0.132686009	8	0.094518712	4	0.0667083	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	RUN domain	RUN domain-containing protein 3B GN=RUNDC3B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: RUN domain-containing protein 3B isoform 1 [Odobenus rosmarus divergens]
ENSG00000105792(CFAP69)	--	1.053590137	65	1.404909669	51	2.351289323	83	1.589463555	59	1.157976492	72	1.589465593	54	0.972559733	-0.166425785	normal	0.922165811	0.464432723	normal	0.801712619	-0.614458282	normal	0.867378944	-0.125831429	normal	--	--	--	--	--	--	--	--	Cilia- and flagella-associated protein 69 {ECO:0000312|HGNC:HGNC:26107} OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C7orf63 homolog isoform X3 [Galeopterus variegatus]
ENSG00000105793(GTPBP10)	--	27.1264858	1541	28.47128592	1585	28.48725601	1588	34.0845761	1880	29.8190148	1648	40.80742089	2195	0.949217726	0.255802333	normal	0.984083374	0.034774306	normal	0.536786691	0.458345757	normal	0.172227103	0.259060739	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	50S ribosome-binding GTPase;; GTP1/OBG;; Ferrous iron transport protein B;; Elongation factor Tu GTP binding domain	GTP-binding protein 10 GN=GTPBP10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GTP-binding protein 10 isoform X1 [Bubalus bubalis]
ENSG00000105808(RASA4)	--	13.38604846	645	16.7782068	857	13.43033609	720	11.38518599	449	12.41391488	527	14.45353089	621	0.204094975	-0.551830906	normal	0.007048716	-0.721278799	normal	0.944181585	-0.221194331	normal	0.036371923	-0.496834598	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; Biological Process: regulation of GTPase activity (GO:0043087);; 	"K17630|0|hsa:10156|RASA4, CAPRI, GAPL; RAS p21 protein activator 4; K17630 Ras GTPase-activating protein 4 (A)"	Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; C2 domain;; BTK motif;; PH domain	Ras GTPase-activating protein 4 GN=RASA4 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: putative Ras GTPase-activating protein 4B isoform X1 [Galeopterus variegatus]
ENSG00000105810(CDK6)	--	9.7952	1704	13.17571	2161	12.08453	1954	15.20854	2493	13.50169	2353	17.81995	2742	0.276679715	0.517737273	normal	0.98492942	0.101307736	normal	0.455664446	0.480191485	normal	0.019802142	0.361982984	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K02091|0|ptr:746968|CDK6; cyclin-dependent kinase 6; K02091 cyclin-dependent kinase 6 [EC:2.7.11.22] (A)	Cell cycle (ko04110);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Hepatitis B (ko05161);; Measles (ko05162);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Glioma (ko05214);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family;; Lipopolysaccharide kinase (Kdo/WaaP) family	Cyclin-dependent kinase 6 GN=CDK6 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 6 [Galeopterus variegatus]
ENSG00000105819(PMPCB)	--	40.0958	1302	38.4343	1256	38.8465	1240	40.5715	1347	43.0366	1411	37.9747	1259	0.982608598	0.018167062	normal	0.974014673	0.146288716	normal	0.982064966	0.013630223	normal	0.817737445	0.059485807	normal	[R]	General function prediction only	--	K17732|0|mcf:102127994|PMPCB; peptidase (mitochondrial processing) beta (EC:3.4.24.64); K17732 mitochondrial-processing peptidase subunit beta [EC:3.4.24.64] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Insulinase (Peptidase family M16);; Peptidase M16 inactive domain	Mitochondrial-processing peptidase subunit beta (Precursor) GN=PMPCB OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: mitochondrial-processing peptidase subunit beta [Ceratotherium simum simum]
ENSG00000105821(DNAJC2)	--	13.834767	681	15.442206	760	17.86994648	861	16.788529	835	18.6697896	916	15.238905	751	0.924867469	0.262753051	normal	0.936161569	0.247472538	normal	0.953003487	-0.205105712	normal	0.693997839	0.099081124	normal	[JO]	"Translation, ribosomal structure and biogenesis;; Posttranslational modification, protein turnover, chaperones"	--	"K09522|0|ptr:743112|DNAJC2, ZRF1; DnaJ (Hsp40) homolog, subfamily C, member 2; K09522 DnaJ homolog subfamily C member 2 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Myb-like DNA-binding domain;; DnaJ domain;; Myb-like DNA-binding domain	"DnaJ homolog subfamily C member 2, N-terminally processed GN=DNAJC2 OS=Homo sapiens (Human) PE=1 SV=4"	B	Chromatin structure and dynamics	PREDICTED: dnaJ homolog subfamily C member 2 isoform X1 [Mustela putorius furo] 
ENSG00000105825(TFPI2)	--	208.51174	6556	176.57178	5601	185.74793	5818	100.16304	3192	97.81247	3150	119.54375	3839	1.06E-08	-1.068820233	down	7.24E-05	-0.851448145	normal	0.064773379	-0.607888218	normal	1.61E-09	-0.840812585	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Kunitz/Bovine pancreatic trypsin inhibitor domain	Tissue factor pathway inhibitor 2 (Precursor) GN=TFPI2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tissue factor pathway inhibitor 2 isoform X1 [Vicugna pacos]
ENSG00000105829(BET1)	--	31.06531223	505	33.82911079	556	37.94651768	602	34.28782951	563	35.84661603	579	40.51541076	658	0.964617923	0.125657089	normal	0.971821365	0.036953413	normal	0.967494246	0.119744847	normal	0.741325488	0.093693295	normal	--	--	--	K08504|2.86859e-62|ptr:463541|BET1; Bet1 golgi vesicular membrane trafficking protein; K08504 blocked early in transport 1 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain	BET1 homolog GN=BET1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: BET1 homolog [Oryctolagus cuniculus]
ENSG00000105835(NAMPT)	--	35.628832	2124	37.237576	2371	37.253534	2088	52.494424	3062	50.890097	2768	77.3985815	4057	0.387310013	0.496557622	normal	0.975266205	0.201802501	normal	1.47E-06	0.949497842	normal	0.042107079	0.566252113	normal	[H]	Coenzyme transport and metabolism	--	"K03462|0|hsa:10135|NAMPT, 1110035O14Rik, PBEF, PBEF1, VF, VISFATIN; nicotinamide phosphoribosyltransferase (EC:2.4.2.12); K03462 nicotinamide phosphoribosyltransferase [EC:2.4.2.12] (A)"	Nicotinate and nicotinamide metabolism (ko00760)	--	--	Nicotinate phosphoribosyltransferase (NAPRTase) family	Nicotinamide phosphoribosyltransferase GN=NAMPT OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	nicotinamide phosphoribosyltransferase [Sus scrofa] 
ENSG00000105849(TWISTNB)	--	11.2131	679	10.4985	633	10.5954	629	14.5891	895	14.8936	900	10.3444	628	0.797472885	0.366918749	normal	0.426393799	0.485315998	normal	0.974225967	-0.010561487	normal	0.246727622	0.297824907	normal	--	--	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K03004|0|hsa:221830|TWISTNB; TWIST neighbor; K03004 DNA-directed RNA polymerase I subunit RPA43 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020)	[K]	Transcription	SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397	DNA-directed RNA polymerase I subunit RPA43 GN=TWISTNB OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase I subunit RPA43 [Camelus bactrianus]
ENSG00000105852(PON3)	--	22.00716569	476	20.23931644	439	17.9051678	364	12.67778625	281	16.57025467	352	20.8470403	445	0.004033826	-0.787872627	normal	0.854064072	-0.338765848	normal	0.908301708	0.280519722	normal	0.445824709	-0.266839224	normal	--	--	Molecular Function: arylesterase activity (GO:0004064);; Biological Process: biosynthetic process (GO:0009058);; Molecular Function: strictosidine synthase activity (GO:0016844);; 	K01045|0|ptr:463548|PON3; paraoxonase 3; K01045 arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1] (A)	--	--	--	Arylesterase;; SMP-30/Gluconolaconase/LRE-like region;; Strictosidine synthase	Serum paraoxonase/lactonase 3 GN=PON3 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: serum paraoxonase/lactonase 3 [Galeopterus variegatus]
ENSG00000105854(PON2)	--	251.4269293	6632	216.0343747	5747	226.8212772	5958	230.1653528	6137	245.140192	6412	259.3626432	6798	0.991749392	-0.142708305	normal	0.991503643	0.1365048	normal	0.989165241	0.181947532	normal	0.834405785	0.056439153	normal	--	--	Molecular Function: arylesterase activity (GO:0004064);; 	K01045|0|ggo:101147360|PON2; serum paraoxonase/arylesterase 2 isoform 1; K01045 arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1] (A)	--	--	--	Arylesterase;; SMP-30/Gluconolaconase/LRE-like region	Serum paraoxonase/arylesterase 2 GN=PON2 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: serum paraoxonase/arylesterase 2 [Oryctolagus cuniculus]
ENSG00000105855(ITGB8)	--	0.574342095	74	0.594969732	65	0.648755531	83	0.630702442	82	1.072231788	137	1.796125789	224	0.971377132	0.114997644	normal	0.011075204	1.037255148	normal	3.69E-07	1.407783558	up	0.2274788	0.978795972	normal	--	--	--	"K06591|0|hsa:3696|ITGB8; integrin, beta 8; K06591 integrin beta 8 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; EGF-like domain"	Integrin beta-8 (Precursor) GN=ITGB8 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: integrin beta-8 isoform X1 [Galeopterus variegatus]
ENSG00000105856(HBP1)	--	12.344758	492	13.93797726	602	12.41894299	537	9.22183	431	10.6993709	451	18.72601151	765	0.939734895	-0.221064424	normal	0.631281657	-0.436790085	normal	0.35864234	0.501058034	normal	0.996314771	-0.005451555	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ataxin-1 and HBP1 module (AXH);; HMG (high mobility group) box;; HMG-box domain	HMG box-containing protein 1 GN=HBP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: HMG box-containing protein 1 isoform 1 [Trichechus manatus latirostris]
ENSG00000105865(DUS4L)	--	5.92956	221	4.97948	184	5.86816	214	5.67669	213	4.30095	159	4.50274	168	0.964220526	-0.083434293	normal	0.942407152	-0.230069293	normal	0.87814952	-0.354605637	normal	0.553446771	-0.218878413	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: tRNA processing (GO:0008033);; Molecular Function: tRNA dihydrouridine synthase activity (GO:0017150);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	K05545|0|ptr:463652|DUS4L; dihydrouridine synthase 4-like (S. cerevisiae); K05545 tRNA-dihydrouridine synthase 4 [EC:1.3.1.90] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Dihydrouridine synthase (Dus);; NADH:flavin oxidoreductase / NADH oxidase family;; Histidine biosynthesis protein	tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like GN=DUS4L OS=Homo sapiens (Human) PE=2 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like [Felis catus]
ENSG00000105866(SP4)	--	2.931026921	278	2.3822163	219	2.353605558	224	1.9756837	180	1.9001199	178	1.513705	138	0.148012223	-0.653394143	normal	0.901027717	-0.318039282	normal	0.132221477	-0.70103255	normal	0.039709801	-0.561693799	normal	[R]	General function prediction only	--	K09194|0|mcf:102143629|SP4; Sp4 transcription factor; K09194 transcription factor Sp4 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Transcription factor Sp4 GN=SP4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor Sp4 [Ceratotherium simum simum]
ENSG00000105875(WDR91)	--	2.628055996	216	2.691764527	189	2.8031205	203	2.676761679	190	3.345251495	211	1.854327089	170	0.945190031	-0.214237884	normal	0.958190209	0.136396928	normal	0.932162106	-0.262099818	normal	0.796987216	-0.111972799	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 91 GN=WDR91 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 91 [Ceratotherium simum simum]
ENSG00000105877(DNAH11)	--	0.336892991	97	0.309128128	92	0.277751	82	0.170650701	50	0.176268276	52	0.212213925	62	0.110108056	-0.965196286	normal	0.365080359	-0.826236283	normal	0.932023806	-0.403070402	normal	0.079802395	-0.74538344	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:8701|DNAH11, CILD7, DNAHBL, DNAHC11, DNHBL, DPL11; dynein, axonemal, heavy chain 11; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 1;; Microtubule-binding stalk of dynein motor;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D3;; P-loop containing dynein motor region D4;; Dynein heavy chain, N-terminal region 2;; ATP-binding dynein motor region D5;; AAA domain (dynein-related subfamily);; AAA domain;; ATPase family associated with various cellular activities (AAA)"	"Dynein heavy chain 11, axonemal GN=DNAH11 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: dynein heavy chain 11, axonemal [Ceratotherium simum simum]"
ENSG00000105879(CBLL1)	--	11.1012828	670	11.74677381	636	10.46428871	643	11.35895911	639	9.989910889	619	10.93697154	700	0.9701706	-0.098945051	normal	0.97197528	-0.060368405	normal	0.968991474	0.113987733	normal	0.971712671	-0.014307409	normal	--	--	--	"K15685|0|ptr:472482|CBLL1; Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase; K15685 E3 ubiquitin-protein ligase Hakai [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	E3 ubiquitin-protein ligase Hakai GN=CBLL1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase Hakai isoform X3 [Tupaia chinensis]
ENSG00000105887(MTPN)	--	97.94679	4795	101.0255	5019	100.5081	4829	101.662233	5101	93.43064	4621	94.558236	4674	0.992893929	0.058398879	normal	0.989602929	-0.140577254	normal	0.992690358	-0.055340555	normal	0.867818769	-0.046065511	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[K]	Transcription	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Myotrophin GN=MTPN OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: myotrophin [Tupaia chinensis]
ENSG00000105889(STEAP1B)	--	0.541655341	9	0.357222781	6	1.18822763	19	0	0	0.422734575	6	0.211580169	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Ferric reductase like transmembrane component	Metalloreductase STEAP1 GN=STEAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	metalloreductase STEAP1 [Sus scrofa] 
ENSG00000105926(MPP6)	--	7.899856002	511	7.538003905	582	9.132635949	538	11.31874645	588	8.7819079	541	8.099201312	548	0.956654466	0.171180522	normal	0.964500608	-0.126476151	normal	0.972543291	0.018227511	normal	0.963294031	0.018643247	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Guanylate kinase;; L27 domain;; Variant SH3 domain;; PDZ domain (Also known as DHR or GLGF);; SH3 domain	MAGUK p55 subfamily member 6 GN=MPP6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: MAGUK p55 subfamily member 6 isoformX1 [Canis lupus familiaris]
ENSG00000105928(DFNA5)	--	20.17656973	900	16.8507378	765	18.84339076	883	22.62331995	1036	23.17342301	1049	22.10286605	911	0.964753545	0.171921125	normal	0.623394316	0.433322212	normal	0.977839522	0.036684318	normal	0.275653792	0.212282687	normal	--	--	--	--	--	--	--	Gasdermin family	Non-syndromic hearing impairment protein 5 GN=DFNA5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: non-syndromic hearing impairment protein 5 [Tupaia chinensis]
ENSG00000105929(ATP6V0A4)	--	0.22216	14	0.318939856	17	0.27733224	16	0.446038	25	0.362971	19	0.508479	31	0.964278799	0.743902696	normal	--	--	--	0.911646663	0.884876909	normal	--	--	--	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V0 domain (GO:0033179);; "	"K02154|0|hsa:50617|ATP6V0A4, A4, ATP6N1B, ATP6N2, RDRTA2, RTA1C, RTADR, STV1, VPH1, VPP2; ATPase, H+ transporting, lysosomal V0 subunit a4 (EC:3.6.3.14); K02154 V-type H+-transporting ATPase subunit a (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Tuberculosis (ko05152);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	V-type ATPase 116kDa subunit family	V-type proton ATPase 116 kDa subunit a isoform 4 GN=ATP6V0A4 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: V-type proton ATPase 116 kDa subunit a isoform 4 [Panthera tigris altaica]
ENSG00000105939(ZC3HAV1)	--	13.83232113	1650	15.55094597	1784	14.92999158	1612	15.91314063	1872	15.573425	1846	14.60876072	1689	0.977704108	0.151149952	normal	0.985389992	0.027837182	normal	0.984015474	0.05897209	normal	0.739402947	0.078082963	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15259|0|ptr:472529|ZC3HAV1; zinc finger CCCH-type, antiviral 1; K15259 poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain	Zinc finger CCCH-type antiviral protein 1 GN=ZC3HAV1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger CCCH-type antiviral protein 1 [Ceratotherium simum simum]
ENSG00000105948(TTC26)	--	4.895100959	330	6.904706999	341	6.816549898	375	5.57252255	354	5.849462922	357	6.191070804	366	0.966334599	0.070135771	normal	0.966939278	0.044532754	normal	0.968374753	-0.043162193	normal	0.965782714	0.021244936	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Intraflagellar transport protein 56 {ECO:0000250|UniProtKB:Q8BS45} OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 26 [Balaenoptera acutorostrata scammoni]
ENSG00000105953(OGDH)	--	26.58375879	2238	24.47823473	2019	29.65729791	2475	25.38555399	2145	25.36772769	2083	24.78065955	2037	0.985466223	-0.092000128	normal	0.986624508	0.023577984	normal	0.938987801	-0.289078961	normal	0.550674762	-0.12476832	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624);; "	K00164|0|pps:100976371|OGDH; oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide); K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] (A)	Citrate cycle (TCA cycle) (ko00020);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Carbon metabolism (ko01200)	[G]	Carbohydrate transport and metabolism	"Dehydrogenase E1 component;; Transketolase, pyrimidine binding domain"	"2-oxoglutarate dehydrogenase, mitochondrial (Precursor) GN=OGDH OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: 2-oxoglutarate dehydrogenase, mitochondrial isoform X1 [Bos mutus] "
ENSG00000105963(ADAP1)	--	2.877972411	88	1.561212701	73	1.917060049	90	2.704694803	97	1.706176751	78	2.066932526	96	0.96936308	0.107854986	normal	0.971668312	0.072694102	normal	0.970081201	0.083459916	normal	0.897981465	0.089526012	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; 	--	--	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; PH domain;; Pleckstrin homology domain	Arf-GAP with dual PH domain-containing protein 1 GN=ADAP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: arf-GAP with dual PH domain-containing protein 1 isoform X1 [Tupaia chinensis]
ENSG00000105967(TFEC)	--	0.033880555	3	0.136515831	7	0.02288713	1	0.050906818	4	0.043261412	1	0.069086543	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K15591|0|pps:100995454|TFEC; transcription factor EC; K15591 transcription factor EC (A)	--	[K]	Transcription	Domain of unknown function (DUF3371);; Helix-loop-helix DNA-binding domain	Transcription factor EC GN=TFEC OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: transcription factor EC [Camelus bactrianus] 
ENSG00000105968(H2AFV)	--	97.17081374	3239	98.348124	3650	95.388651	3285	111.70124	4563	112.1296	4207	118.476819	4632	0.597327516	0.463415924	normal	0.984010758	0.183397973	normal	0.48457287	0.487260637	normal	0.016450473	0.376270832	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|8.31813e-73|fpg:101921158|histone H2A.V-like; K11251 histone H2A (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H2A.V GN=H2AFV OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2A.V-like [Echinops telfairi]
ENSG00000105971(CAV2)	--	40.441667	1842	42.9385973	1996	52.149187	2225	69.194013	3144	51.54036	2298	44.02137171	1939	0.001597019	0.740018243	normal	0.975954915	0.181712127	normal	0.970661142	-0.206633401	normal	0.497878959	0.261308299	normal	--	--	Biological Process: caveola assembly (GO:0070836);; 	K12958|1.305e-115|ptr:736452|CAV2; caveolin 2; K12958 caveolin 2 (A)	Endocytosis (ko04144);; Focal adhesion (ko04510);; Bacterial invasion of epithelial cells (ko05100);; Proteoglycans in cancer (ko05205)	--	--	Caveolin	Caveolin-2 GN=CAV2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: caveolin-2 [Tupaia chinensis]
ENSG00000105974(CAV1)	--	178.7038826	6742	221.45609	8108	234.75127	8319	361.5241842	13695	227.0647291	8433	206.3075321	7687	3.47E-07	0.991406815	normal	0.995335633	0.035266858	normal	0.993819012	-0.122257763	normal	0.510571226	0.340866477	normal	--	--	Biological Process: caveola assembly (GO:0070836);; 	"K06278|6.86267e-130|ptr:463670|CAV1; caveolin 1, caveolae protein, 22kDa; K06278 caveolin 1 (A)"	Endocytosis (ko04144);; Focal adhesion (ko04510);; Bacterial invasion of epithelial cells (ko05100);; Proteoglycans in cancer (ko05205);; Viral myocarditis (ko05416)	--	--	Caveolin	Caveolin-1 GN=CAV1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	caveolin-1 [Equus caballus] 
ENSG00000105976(MET)	--	67.460777	8087	57.57344466	7024	68.98552785	7846	83.15627932	9683	66.04006166	7760	62.99821493	7221	0.987585605	0.228977422	normal	0.9932443	0.122312189	normal	0.993310128	-0.128024405	normal	0.765800969	0.081427966	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05099|0|hsa:4233|MET, AUTS9, HGFR, RCCP2, c-Met; MET proto-oncogene, receptor tyrosine kinase (EC:2.7.10.1); K05099 proto-oncogene tyrosine-protein kinase Met [EC:2.7.10.1] (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Bacterial invasion of epithelial cells (ko05100);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Malaria (ko05144);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Melanoma (ko05218);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	Sema domain;; Protein tyrosine kinase;; Protein kinase domain;; IPT/TIG domain;; Plexin repeat	Hepatocyte growth factor receptor (Precursor) GN=MET OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: hepatocyte growth factor receptor [Galeopterus variegatus]
ENSG00000105982(RNF32)	--	5.149462372	48	1.149436	43	0.777750458	29	2.032127763	36	0.974687657	34	1.188097005	44	0.959900584	-0.429921162	normal	0.969782318	-0.346491722	normal	0.943608583	0.568917535	normal	0.926716713	-0.095332379	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Anaphase-promoting complex subunit 11 RING-H2 finger;; Zinc finger, C3HC4 type (RING finger);; IQ calmodulin-binding motif"	RING finger protein 32 GN=RNF32 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 32 [Oryctolagus cuniculus] 
ENSG00000105983(LMBR1)	--	79.702059	1833	61.51694574	1710	66.03813	1641	66.39575624	1833	58.7996252	1733	73.49186405	1658	0.985797908	-0.030806442	normal	0.985078187	-0.00214934	normal	0.985032377	0.006571301	normal	0.977448148	-0.010526278	normal	--	--	--	--	--	[V]	Defense mechanisms	LMBR1-like membrane protein	Limb region 1 protein homolog GN=LMBR1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: limb region 1 protein homolog [Oryctolagus cuniculus]
ENSG00000105989(WNT2)	--	0	0	0	0	0	0	0	0	0	0	0.021117203	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00182|0|hsa:7472|WNT2, INT1L1, IRP; wingless-type MMTV integration site family member 2; K00182 wingless-type MMTV integration site family, member 2 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-2 (Precursor) GN=WNT2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein Wnt-2 [Pteropus alecto]
ENSG00000105991(HOXA1)	--	2.74703	106	2.67518	98	2.5994	98	2.459289	95	2.9758	112	2.72793	106	0.962225121	-0.186046682	normal	0.961520349	0.168780867	normal	0.968137303	0.103384846	normal	0.972572149	0.030752066	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09301|0|hsa:3198|HOXA1, BSAS, HOX1, HOX1F; homeobox A1; K09301 homeobox protein HoxA/B/D1 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-A1 GN=HOXA1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein Hox-A1 isoform X1 [Galeopterus variegatus]
ENSG00000105993(DNAJB6)	--	57.7054794	1868	56.31643977	1914	62.9499973	2079	68.80851452	2358	66.97277105	2164	59.71169922	2029	0.924420404	0.305013298	normal	0.97895032	0.15556746	normal	0.986646543	-0.043380392	normal	0.494433676	0.139083866	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09512|8.76166e-74|mcf:102126873|DNAJB6; DnaJ (Hsp40) homolog, subfamily B, member 6; K09512 DnaJ homolog subfamily B member 6 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily B member 6 GN=DNAJB6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 6-like [Echinops telfairi]
ENSG00000105996(HOXA2)	--	1.41395	44	0.93693	29	0.821537	25	1.09887	34	0.900421	28	0.571148	18	0.967917188	-0.38736765	normal	0.984284992	-0.068421211	normal	0.980513214	-0.450011883	normal	0.705643346	-0.316296967	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09302|0|ptr:472322|HOXA2; homeobox A2; K09302 homeobox protein HoxA/B2 (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-A2 GN=HOXA2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox protein Hox-A2 [Bos mutus] 
ENSG00000105997(HOXA3)	--	12.69625586	357	12.19456801	300	12.94493301	387	12.16824713	387	13.16653238	426	11.99944047	411	0.965776631	0.085224905	normal	0.534153093	0.482414158	normal	0.966973876	0.078216759	normal	0.438733165	0.208845191	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09303|0|hsa:3200|HOXA3, HOX1, HOX1E; homeobox A3; K09303 homeobox protein HoxA/B/D3 (A)"	--	[R]	General function prediction only	Domain of unknown function (DUF4074);; Homeobox domain	Homeobox protein Hox-A3 GN=HOXA3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	homeobox protein Hox-A3 [Oryctolagus cuniculus] 
ENSG00000106003(LFNG)	--	5.621871308	245	4.4745382	191	4.149720148	200	7.72979033	305	6.580905674	293	4.48476528	194	0.911925479	0.283598717	normal	0.292916213	0.592089899	normal	0.966033334	-0.051836794	normal	0.427630066	0.293987408	normal	--	--	"Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K05948|0|hsa:3955|LFNG, SCDO3; LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222); K05948 fringe [EC:2.4.1.222] (A)"	Other types of O-glycan biosynthesis (ko00514);; Notch signaling pathway (ko04330)	--	--	Fringe-like	"Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe GN=LFNG OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-N-acetylglucosaminyltransferase lunatic fringe [Camelus dromedarius]"
ENSG00000106004(HOXA5)	--	3.01979447	140	2.835540784	181	2.607091906	144	3.488604	174	3.892601958	209	2.8772458	178	0.931163336	0.280066957	normal	0.950857856	0.184650019	normal	0.924299715	0.294728182	normal	0.510898452	0.249492661	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09305|3.98282e-138|hsa:3202|HOXA5, HOX1, HOX1.3, HOX1C; homeobox A5; K09305 homeobox protein HoxA/B/C5 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-A5 GN=HOXA5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein Hox-A5 [Trichechus manatus latirostris]
ENSG00000106009(BRAT1)	--	24.2512	1215	21.3342	1089	22.2926	1153	21.0756	1053	22.0079	1098	20.7183	1044	0.947556995	-0.236960912	normal	0.980101785	-0.009539265	normal	0.970725936	-0.151353525	normal	0.532841183	-0.134867427	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	HEAT repeat;; HEAT repeats;; HEAT-like repeat	BRCA1-associated ATM activator 1 GN=BRAT1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: BRCA1-associated ATM activator 1 [Galeopterus variegatus]
ENSG00000106012(IQCE)	--	6.727577549	990	6.638730438	1023	6.947343232	1003	8.387336763	1157	8.271797471	1199	7.970257009	1100	0.961324518	0.193777784	normal	0.958070817	0.207315633	normal	0.973758508	0.124710868	normal	0.38177421	0.175148368	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	IQ calmodulin-binding motif	IQ domain-containing protein E GN=IQCE OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: IQ domain-containing protein E isoform X5 [Tupaia chinensis]
ENSG00000106013(ANKRD7)	--	0.528377017	8	1.11224054	17	0.327049302	4	0.259591828	4	0.722045	9	0.408496922	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 7 GN=ANKRD7 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 7-like [Leptonychotes weddellii]
ENSG00000106018(VIPR2)	--	0.028325389	2	0	0	0.013653927	0	0	0	0.027479898	1	0.055986967	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	K04590|0|nle:100579702|VIPR2; vasoactive intestinal peptide receptor 2; K04590 vasoactive intestinal peptide receptor 2 (A)	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Vasoactive intestinal polypeptide receptor 2 (Precursor) GN=VIPR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: vasoactive intestinal polypeptide receptor 2 [Ochotona princeps]
ENSG00000106025(TSPAN12)	--	2.10042466	76	2.1289646	84	3.154855222	92	0.868402437	25	1.15704195	29	0.509166801	12	0.000941783	-1.576532691	down	0.000880313	-1.507447522	down	6.28E-11	-2.798644402	down	3.77E-06	-1.955403537	down	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17355|0|ptr:463678|TSPAN12; tetraspanin 12; K17355 tetraspanin-12 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-12 GN=TSPAN12 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tetraspanin-12 [Oryctolagus cuniculus] 
ENSG00000106028(SSBP1)	--	124.424478	1050	141.0854353	1196	144.557269	1216	156.4207805	1364	160.0631586	1314	133.3795109	1142	0.849059099	0.346176562	normal	0.976851587	0.114183551	normal	0.977844033	-0.098745274	normal	0.581028229	0.120391054	normal	[L]	"Replication, recombination and repair"	Molecular Function: single-stranded DNA binding (GO:0003697);; 	"K03111|3.76327e-105|ptr:741448|SSBP1; single-stranded DNA binding protein 1, mitochondrial; K03111 single-strand DNA-binding protein (A)"	DNA replication (ko03030);; Mismatch repair (ko03430);; Homologous recombination (ko03440)	[L]	"Replication, recombination and repair"	Single-strand binding protein family	"Single-stranded DNA-binding protein, mitochondrial (Precursor) GN=SSBP1 OS=Homo sapiens (Human) PE=1 SV=1"	L	"Replication, recombination and repair"	"PREDICTED: single-stranded DNA-binding protein, mitochondrial [Condylura cristata]"
ENSG00000106031(HOXA13)	--	1.511743	112	1.775473953	130	1.624286927	118	1.459496	110	1.523916	116	1.1127632	86	0.969282186	-0.056051561	normal	0.957175862	-0.183551477	normal	0.863974122	-0.457768789	normal	0.63730608	-0.228330782	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09298|6.27238e-149|pon:100435280|HOXA13; homeobox A13; K09298 homeobox protein HoxA/C/D13 (A)	--	[K]	Transcription	Hox protein A13 N terminal;; Homeobox domain	Homeobox protein Hox-A13 GN=HOXA13 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-A13 [Ceratotherium simum simum]
ENSG00000106034(CPED1)	--	0.194809042	11	0.027437218	1	0.374595343	14	0.0203975	2	0.061487952	2	0.053760438	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p;; Cadherin-like beta sandwich domain	Cadherin-like and PC-esterase domain-containing protein 1 (Precursor) GN=CPED1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: cadherin-like and PC-esterase domain-containing protein 1 isoform X1 [Equus caballus] 
ENSG00000106038(EVX1)	--	0.044722198	2	0	0	0.043557166	0	0.091928992	2	0.103444758	4	0.021811584	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K09320|0|hsa:2128|EVX1; even-skipped homeobox 1; K09320 homeobox even-skipped homolog protein (A)	--	[K]	Transcription	Homeobox domain	Homeobox even-skipped homolog protein 1 GN=EVX1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox even-skipped homolog protein 1 [Galeopterus variegatus]
ENSG00000106049(HIBADH)	--	37.50006	1020	33.01295699	906	44.50971139	964	43.3584445	1179	49.16607571	1229	47.40075821	1084	0.965602496	0.177912885	normal	0.679183083	0.417874442	normal	0.968018331	0.160730359	normal	0.163603287	0.25161849	normal	[I]	Lipid transport and metabolism	Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00020|0|pps:100975479|HIBADH; 3-hydroxyisobutyrate dehydrogenase; K00020 3-hydroxyisobutyrate dehydrogenase [EC:1.1.1.31] (A)	"Valine, leucine and isoleucine degradation (ko00280)"	[R]	General function prediction only	"NAD binding domain of 6-phosphogluconate dehydrogenase;; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase;; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; NADP oxidoreductase coenzyme F420-dependent"	"3-hydroxyisobutyrate dehydrogenase, mitochondrial (Precursor) GN=HIBADH OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: 3-hydroxyisobutyrate dehydrogenase, mitochondrial isoform 1 [Canis lupus familiaris]"
ENSG00000106052(TAX1BP1)	--	46.35362825	3115	47.72377877	3234	49.6582992	3255	44.06033205	3030	45.74044548	3081	45.10379443	2993	0.989392385	-0.070711267	normal	0.98860023	-0.091303805	normal	0.986701884	-0.129294041	normal	0.659975081	-0.098308071	normal	--	--	--	--	--	--	--	Calcium binding and coiled-coil domain (CALCOCO1) like	Tax1-binding protein 1 GN=TAX1BP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: tax1-binding protein 1 homolog isoform X1 [Equus caballus] 
ENSG00000106066(CPVL)	--	1.0547819	32	0.808628417	24	0.649256538	22	2.25604734	74	2.754010034	86	2.916299	101	0.087661373	1.141629995	normal	4.98E-05	1.757686972	up	6.05E-08	2.116346373	up	3.32E-05	1.721910224	up	--	--	Molecular Function: serine-type carboxypeptidase activity (GO:0004185);; Biological Process: proteolysis (GO:0006508);; 	"K09645|0|hsa:54504|CPVL, HVLP; carboxypeptidase, vitellogenic-like; K09645 vitellogenic carboxypeptidase-like protein [EC:3.4.16.-] (A)"	--	[OE]	"Posttranslational modification, protein turnover, chaperones;; Amino acid transport and metabolism"	Serine carboxypeptidase	Probable serine carboxypeptidase CPVL (Precursor) GN=CPVL OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable serine carboxypeptidase CPVL [Ceratotherium simum simum]
ENSG00000106069(CHN2)	--	0.172650874	8	0	0	0	0	1.101727708	15	0.35552973	13	1.319117933	33	--	--	--	--	--	--	1.29E-06	4.508346642	up	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; SH2 domain	Beta-chimaerin GN=CHN2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: beta-chimaerin isoform X2 [Tupaia chinensis]
ENSG00000106070(GRB10)	--	21.13736871	1687	16.73788534	1554	19.31498897	1507	29.48808028	2586	32.31479197	2710	25.55637358	2214	0.082059151	0.584996772	normal	0.000685974	0.780297748	normal	0.170844087	0.546229424	normal	4.77E-06	0.639805227	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	BPS (Between PH and SH2);; SH2 domain;; Ras association (RalGDS/AF-6) domain;; PH domain	Growth factor receptor-bound protein 10 GN=GRB10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: growth factor receptor-bound protein 10 isoform X1 [Tupaia chinensis]
ENSG00000106077(ABHD11)	--	11.45087365	301	10.58541175	255	10.365594	276	10.215199	265	10.20246206	266	7.69354243	204	0.942113991	-0.213441219	normal	0.965589409	0.039274388	normal	0.725929384	-0.441565339	normal	0.534127754	-0.200698882	normal	[R]	General function prediction only	--	K13703|0|ptr:472412|ABHD11; abhydrolase domain containing 11; K13703 abhydrolase domain-containing protein 11 (A)	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; PGAP1-like protein;; Thioesterase domain;; Putative esterase;; Chlorophyllase enzyme;; Lipase (class 3)	Alpha/beta hydrolase domain-containing protein 11 GN=ABHD11 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: alpha/beta hydrolase domain-containing protein 11 isoform X2 [Tupaia chinensis]
ENSG00000106078(COBL)	--	4.570970538	405	3.349996057	249	3.467667964	326	8.038509746	800	8.038569798	748	7.281436645	671	1.73E-05	0.948638916	normal	2.49E-14	1.559730483	up	2.88E-06	1.029748614	up	1.23E-11	1.157441623	up	--	--	Molecular Function: actin binding (GO:0003779);; 	K18623|0|hsa:23242|COBL; cordon-bleu WH2 repeat protein; K18623 protein cordon-bleu (A)	--	--	--	Cordon-bleu ubiquitin-like domain;; WH2 motif	Protein cordon-bleu GN=COBL OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein cordon-bleu [Galeopterus variegatus]
ENSG00000106080(FKBP14)	--	11.160213	527	13.57813	580	9.855464422	531	15.77842	740	16.59096	646	15.376673	623	0.529384377	0.457759109	normal	0.96453471	0.133724217	normal	0.941922857	0.221645512	normal	0.183081178	0.272703185	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K09577|8.36049e-140|ptr:463324|FKBP14; FK506 binding protein 14, 22 kDa; K09577 FK506-binding protein 14 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; EF-hand domain pair;; EF hand	Peptidyl-prolyl cis-trans isomerase FKBP14 (Precursor) GN=FKBP14 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP14 [Orcinus orca] 
ENSG00000106086(PLEKHA8)	--	5.564400869	497	5.679033314	536	4.946175086	521	6.237913051	605	5.837436056	589	6.789594299	671	0.926623014	0.25214964	normal	0.96608221	0.114300364	normal	0.819090826	0.355825542	normal	0.265276981	0.242289439	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Molecular Function: glycolipid transporter activity (GO:0017089);; Biological Process: glycolipid transport (GO:0046836);; Molecular Function: glycolipid binding (GO:0051861);; 	"K08051|0|hsa:84725|PLEKHA8, FAPP2; pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8; K08051 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 (A)"	--	--	--	Glycolipid transfer protein (GLTP);; PH domain	Pleckstrin homology domain-containing family A member 8 GN=PLEKHA8 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: pleckstrin homology domain-containing family A member 8 [Oryctolagus cuniculus]
ENSG00000106089(STX1A)	--	9.474842656	444	10.64696093	508	11.1206731	532	11.13773136	525	12.80807826	593	12.87719319	606	0.944108758	0.210255809	normal	0.948078485	0.201222179	normal	0.95534859	0.179122719	normal	0.411806356	0.195713992	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: membrane (GO:0016020);; 	K04560|8.01152e-174|asn:102386526|STX1A; syntaxin 1A (brain); K04560 syntaxin 1A (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Syntaxin;; SNARE domain;; Syntaxin-like protein	Syntaxin-1A GN=STX1A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-1A [Chrysochloris asiatica]
ENSG00000106100(NOD1)	--	2.795145471	190	3.167109162	201	2.679094731	185	3.019692301	235	3.220522967	262	4.538646407	271	0.923818206	0.273835043	normal	0.859030056	0.358575712	normal	0.472522846	0.538815779	normal	0.166698787	0.394190152	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K08727|0|hsa:10392|NOD1, CARD4, CLR7.1, NLRC1; nucleotide-binding oligomerization domain containing 1; K08727 nucleotide-binding oligomerization domain-containing protein 1 (A)"	NOD-like receptor signaling pathway (ko04621);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Shigellosis (ko05131);; Pertussis (ko05133)	[S]	Function unknown	NACHT domain;; Leucine Rich repeat;; Caspase recruitment domain;; Leucine Rich repeats (2 copies)	Nucleotide-binding oligomerization domain-containing protein 1 GN=NOD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: nucleotide-binding oligomerization domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000106105(GARS)	--	83.36801	3834	116.2174	4052	142.8625	3806	76.1263	3061	65.31487	2871	91.55510453	4585	0.893595178	-0.355519708	normal	0.345878295	-0.518276373	normal	0.969871329	0.260260384	normal	0.656178816	-0.172865055	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01880|0|hsa:2617|GARS, CMT2D, DSMAV, GlyRS, HMN5, SMAD1; glycyl-tRNA synthetase (EC:6.1.1.14); K01880 glycyl-tRNA synthetase [EC:6.1.1.14] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain;; WHEP-TRS domain"	Glycine--tRNA ligase GN=GARS OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: glycine--tRNA ligase [Equus caballus]
ENSG00000106113(CRHR2)	--	0.022684672	1	0.018888571	1	0	0	0	0	0	0	0.022400768	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04579|0|hsa:1395|CRHR2, CRF-RB, CRF2, CRFR2, HM-CRF; corticotropin releasing hormone receptor 2; K04579 corticotropin releasing hormone receptor 2 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Corticotropin-releasing factor receptor 2 GN=CRHR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: corticotropin-releasing factor receptor 2 isoform X1 [Vicugna pacos]
ENSG00000106123(EPHB6)	--	0.676703238	53	0.595337229	46	0.309807901	22	0.688738857	42	1.207228587	85	0.765065162	60	0.964171626	-0.354850769	normal	0.405852862	0.843706085	normal	0.037607492	1.379536831	normal	0.392200498	0.606816732	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05114|0|ggo:101148916|EPHB6; ephrin type-B receptor 6 isoform 1; K05114 Eph receptor B6 [EC:2.7.10.1] (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; GCC2 and GCC3	Ephrin type-B receptor 6 (Precursor) GN=EPHB6 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: ephrin type-B receptor 6 [Galeopterus variegatus]
ENSG00000106125(MINDY4)	--	1.701047342	110	2.573487605	130	1.765471426	100	2.302427747	130	2.371171981	110	1.76439839	84	0.956035033	0.20750749	normal	0.944188354	-0.259152987	normal	0.954765624	-0.255607085	normal	0.883616512	-0.092366489	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF4205)	Protein FAM188B GN=FAM188B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM188B isoform X1 [Galeopterus variegatus]
ENSG00000106144(CASP2)	--	12.956872	875	12.91895553	901	12.969769	897	13.197755	869	13.716469	910	12.438867	856	0.977303989	-0.040687413	normal	0.977888255	-0.007075302	normal	0.975776011	-0.075658042	normal	0.888366478	-0.041847801	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K02186|0|pps:100984572|CASP2; caspase 2, apoptosis-related cysteine peptidase; K02186 caspase 2 [EC:3.4.22.55] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain;; Caspase recruitment domain	Caspase-2 subunit p12 (Precursor) GN=CASP2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-2 isoformX1 [Equus caballus] 
ENSG00000106153(CHCHD2)	--	319.761	4274	342.521	4691	355.882	4930	374.738	5146	368.754	4917	333.851	4543	0.97811354	0.236954571	normal	0.992672405	0.046441672	normal	0.990439106	-0.126193445	normal	0.84878724	0.050593678	normal	--	--	--	--	--	[S]	Function unknown	CHCH domain	"Coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial (Precursor) GN=CHCHD2 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial [Galeopterus variegatus]"
ENSG00000106178(CCL24)	--	0	0	0	0	0.19926032	0	0	0	0	0	0.4017635	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K05514|1.70602e-83|hsa:6369|CCL24, Ckb-6, MPIF-2, MPIF2, SCYA24; chemokine (C-C motif) ligand 24; K05514 C-C motif chemokine, other (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	C-C motif chemokine 24 (Precursor) GN=CCL24 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C-C motif chemokine 24 [Orycteropus afer afer]
ENSG00000106211(HSPB1)	--	450.68031	5486	483.46187	6039	436.85533	5564	656.520987	8422	832.904379	10249	567.56871	7034	0.12491951	0.587442291	normal	0.003094556	0.741530905	normal	0.948582	0.329851563	normal	0.017530774	0.567365152	normal	--	--	--	K04455|1.18903e-135|ptr:463488|HSPB1; heat shock 27kDa protein 1; K04455 heat shock protein beta-1 (A)	MAPK signaling pathway (ko04010);; VEGF signaling pathway (ko04370);; Amoebiasis (ko05146);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp20/alpha crystallin family	Heat shock protein beta-1 GN=HSPB1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	heat shock protein 27 kDa beta-1 [Canis lupus familiaris]
ENSG00000106236(NPTX2)	--	0	0	0.0203222	1	0.0198886	0	0.020784	1	0	0	0.0205843	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Pentaxin family;; Concanavalin A-like lectin/glucanases superfamily	Neuronal pentraxin-2 (Precursor) GN=NPTX2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: neuronal pentraxin-2 [Bubalus bubalis]
ENSG00000106244(PDAP1)	--	48.0078	2619	44.3577	2471	48.3899	2688	51.7206	2845	51.1734	2776	44.8685	2458	0.987734968	0.088530492	normal	0.983172822	0.146401431	normal	0.984050024	-0.137258879	normal	0.902758197	0.033287471	normal	--	--	--	--	--	[R]	General function prediction only	Casein kinase substrate phosphoprotein PP28	28 kDa heat- and acid-stable phosphoprotein GN=PDAP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: 28 kDa heat- and acid-stable phosphoprotein [Chrysochloris asiatica]
ENSG00000106245(BUD31)	--	44.4723	968	43.3151145	936	42.8328	935	46.0158	1016	45.6473	991	44.6453	982	0.978884215	0.038928874	normal	0.977222027	0.060854411	normal	0.977626459	0.06236678	normal	0.847472937	0.052962157	normal	[KD]	"Transcription;; Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	K12873|8.03856e-103|ssc:100520297|BUD31; BUD31 homolog (S. cerevisiae); K12873 bud site selection protein 31 (A)	Spliceosome (ko03040)	[K]	Transcription	G10 protein	Protein BUD31 homolog GN=BUD31 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	Protein BUD31 like protein [Myotis brandtii]
ENSG00000106246(PTCD1)	--	506.629189	2023	512.6280023	2022	579.258441	2169	583.369347	2475	557.4773184	2202	523.64704	2210	0.954762711	0.259921233	normal	0.984209058	0.101532133	normal	0.987612683	0.01871195	normal	0.542395782	0.126912323	normal	--	--	--	K17710|0|hsa:26024|PTCD1; pentatricopeptide repeat domain 1; K17710 pentatricopeptide repeat domain-containing protein 1 (A)	--	[R]	General function prediction only	PPR repeat family;; PPR repeat;; Pentatricopeptide repeat domain;; PPR repeat	"Pentatricopeptide repeat-containing protein 1, mitochondrial GN=PTCD1 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: pentatricopeptide repeat-containing protein 1, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000106258(CYP3A5)	--	0.2583255	13	0.6101132	15	0.181832001	11	3.815421	208	3.430038	202	2.815172	148	0	3.820362666	up	0	3.603138337	up	0	3.571098112	up	6.86E-27	3.816167587	up	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17690|0|hsa:1577|CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3; cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1); K17690 cytochrome P450, family 3, subfamily A, polypeptide 5 [EC:1.14.14.1] (A)"	Steroid hormone biosynthesis (ko00140);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 3A5 GN=CYP3A5 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	cytochrome P450 3A89 [Equus caballus] 
ENSG00000106261(ZKSCAN1)	--	8.45752653	1603	7.979137372	1542	8.497049005	1602	9.105594345	1704	8.69395	1662	10.16329105	1862	0.984063338	0.057265409	normal	0.981998075	0.086609232	normal	0.966696805	0.208504755	normal	0.580739191	0.118342432	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09229|0|ggo:101154220|ZKSCAN1; zinc finger protein with KRAB and SCAN domains 1; K09229 KRAB and SCAN domains-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box"	Zinc finger protein with KRAB and SCAN domains 1 GN=ZKSCAN1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein with KRAB and SCAN domains 1 [Odobenus rosmarus divergens]
ENSG00000106263(EIF3B)	--	95.266976	6152	91.945025	6038	94.69915	6252	111.25985	7214	109.893605	7085	88.50947	5695	0.988108647	0.198865757	normal	0.986705759	0.209222122	normal	0.99124531	-0.142877153	normal	0.690306296	0.094787562	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K03253|0|hsa:8662|EIF3B, EIF3-ETA, EIF3-P110, EIF3-P116, EIF3S9, PRT1; eukaryotic translation initiation factor 3, subunit B; K03253 translation initiation factor 3 subunit B (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	"Eukaryotic translation initiation factor eIF2A;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Eukaryotic translation initiation factor 3 subunit B {ECO:0000255|HAMAP-Rule:MF_03001} OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit B [Galeopterus variegatus]
ENSG00000106266(SNX8)	--	16.43016687	1247	20.00516569	1655	19.3420567	1442	12.55034488	1162	13.79999539	1205	17.88612627	1647	0.97466382	-0.132514467	normal	0.450890395	-0.478709645	normal	0.970450996	0.183297956	normal	0.728258727	-0.134205323	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K17922|0|hsa:29886|SNX8, Mvp1; sorting nexin 8; K17922 sorting nexin-8 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain	Sorting nexin-8 GN=SNX8 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-8 [Condylura cristata]
ENSG00000106268(NUDT1)	--	58.15955002	555	63.19459083	615	63.65658269	634	45.572925	448	45.0064855	418	48.09996773	461	0.846844427	-0.338775077	normal	0.161227116	-0.576778238	normal	0.510945323	-0.466696346	normal	0.013979303	-0.464041915	normal	[LR]	"Replication, recombination and repair;; General function prediction only"	Molecular Function: hydrolase activity (GO:0016787);; 	K17816|4.70786e-105|ptr:463225|NUDT1; nudix (nucleoside diphosphate linked moiety X)-type motif 1; K17816 8-oxo-dGTP diphosphatase / 2-hydroxy-dATP diphosphatase [EC:3.6.1.55 3.6.1.56] (A)	--	--	--	NUDIX domain	"7,8-dihydro-8-oxoguanine triphosphatase (Precursor) GN=NUDT1 OS=Homo sapiens (Human) PE=1 SV=3"	L	"Replication, recombination and repair"	"PREDICTED: 7,8-dihydro-8-oxoguanine triphosphatase isoform X1 [Galeopterus variegatus]"
ENSG00000106290(TAF6)	--	34.56354384	1589	35.53683107	1538	37.309836	1628	32.670824	1392	34.61774041	1436	33.906674	1443	0.959657116	-0.221563067	normal	0.978551854	-0.120303858	normal	0.970594196	-0.182141009	normal	0.358906134	-0.175860509	normal	[K]	Transcription	"Cellular Component: nucleus (GO:0005634);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; Biological Process: regulation of sequence-specific DNA binding transcription factor activity (GO:0051090);; "	K03131|0|ggo:101124001|TAF6; transcription initiation factor TFIID subunit 6 isoform 1; K03131 transcription initiation factor TFIID subunit 6 (A)	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	Protein of unknown function (DUF1546);; TATA box binding protein associated factor (TAF)	Transcription initiation factor TFIID subunit 6 GN=TAF6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 6 isoform 2 [Orcinus orca]
ENSG00000106299(WASL)	--	15.3441	1102	18.5172	1313	17.2793	1213	16.8439	1208	16.0399	1150	18.9316	1365	0.977267249	0.101528742	normal	0.958632671	-0.212397985	normal	0.971475768	0.161839654	normal	0.962333677	0.016409887	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	K05747|0|ptr:463688|WASL; Wiskott-Aldrich syndrome-like; K05747 Wiskott-Aldrich syndrome protein (A)	Chemokine signaling pathway (ko04062);; Adherens junction (ko04520);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132);; Choline metabolism in cancer (ko05231)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	WH1 domain;; P21-Rho-binding domain;; WH2 motif	Neural Wiskott-Aldrich syndrome protein GN=WASL OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: neural Wiskott-Aldrich syndrome protein isoform X1 [Bos taurus]
ENSG00000106302(HYAL4)	--	0	0	0	0	0.081858549	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hyalurononglucosaminidase activity (GO:0004415);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K01197|0|hsa:23553|HYAL4, CSHY; hyaluronoglucosaminidase 4 (EC:3.2.1.35); K01197 hyaluronoglucosaminidase [EC:3.2.1.35] (A)"	Glycosaminoglycan degradation (ko00531)	--	--	Hyaluronidase	Hyaluronidase-4 GN=HYAL4 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: hyaluronidase-4 [Physeter catodon]
ENSG00000106305(AIMP2)	--	27.919584	534	27.641799	533	30.724073	594	27.000869	521	28.620051	554	25.906922	503	0.970305148	-0.0661958	normal	0.971426952	0.034228627	normal	0.92942206	-0.247510356	normal	0.740010049	-0.095008314	normal	--	--	--	"K15438|0|hsa:7965|AIMP2, JTV-1, JTV1, P38; aminoacyl tRNA synthetase complex-interacting multifunctional protein 2; K15438 aminoacyl tRNA synthase complex-interacting multifunctional protein 2 (A)"	--	--	--	"Glutathione S-transferase, C-terminal domain"	Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 GN=AIMP2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: aminoacyl tRNA synthase complex-interacting multifunctional protein 2 isoform X1 [Tupaia chinensis]
ENSG00000106327(TFR2)	--	0.89924487	47	0.799263438	45	0.9439527	51	1.018473678	54	1.201455379	65	0.911819046	50	0.976158004	0.164448498	normal	0.922403015	0.49517434	normal	0.978555676	-0.035788777	normal	0.758315786	0.219917961	normal	--	--	--	--	--	[OPR]	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism;; General function prediction only"	Transferrin receptor-like dimerisation domain;; Peptidase family M28;; PA domain	Transferrin receptor protein 2 GN=TFR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: transferrin receptor protein 2 [Galeopterus variegatus]
ENSG00000106328(FSCN3)	--	0.029919061	1	0.029806232	1	0.117888009	0	0	0	0.118285143	0	0.119733054	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: protein binding, bridging (GO:0030674);; Molecular Function: actin filament binding (GO:0051015);; "	"K17456|0|hsa:29999|FSCN3; fascin actin-bundling protein 3, testicular; K17456 fascin 3 (A)"	--	--	--	Fascin domain;; FRG1-like family;; Fibroblast growth factor;; Protein of unknown function (DUF569)	Fascin-3 GN=FSCN3 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: fascin-3 isoform X1 [Oryctolagus cuniculus]
ENSG00000106330(MOSPD3)	--	20.60262328	363	13.03324038	235	16.86799724	306	12.12585846	216	14.61649944	260	13.01424801	230	0.010965929	-0.77546425	normal	0.959299929	0.123667491	normal	0.756531768	-0.417799264	normal	0.220825322	-0.377448424	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	MSP (Major sperm protein) domain	Motile sperm domain-containing protein 3 GN=MOSPD3 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: motile sperm domain-containing protein 3 isoform X1 [Tupaia chinensis] 
ENSG00000106333(PCOLCE)	--	3.866239886	95	2.646396708	65	2.06765002	55	2.522631172	61	2.589111137	61	2.614621895	63	0.68637827	-0.656584396	normal	0.973011855	-0.110404897	normal	0.972229233	0.182926065	normal	0.702729371	-0.238441257	normal	--	--	--	--	--	--	--	CUB domain;; UNC-6/NTR/C345C module;; CUB-like domain	Procollagen C-endopeptidase enhancer 1 (Precursor) GN=PCOLCE OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: procollagen C-endopeptidase enhancer 1 isoform 3 [Canis lupus familiaris]
ENSG00000106336(FBXO24)	--	0.3200136	14	0.39902424	9	0.0701217	0	0.089696468	4	0.087962915	3	0.2279909	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10304|0|hsa:26261|FBXO24, FBX24; F-box protein 24; K10304 F-box protein 24 (A)"	--	[R]	General function prediction only	F-box-like;; F-box domain;; Regulator of chromosome condensation (RCC1) repeat	F-box only protein 24 GN=FBXO24 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	F-box only protein 24 [Pteropus alecto]
ENSG00000106344(RBM28)	--	18.98329795	1381	22.23834559	1485	20.90007489	1370	16.11462613	1291	19.75637336	1549	18.65057778	1440	0.9766605	-0.127909356	normal	0.983302479	0.03940836	normal	0.982076996	0.063533065	normal	0.986272296	-0.005988585	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K14573|0|ptr:739989|RBM28; RNA binding motif protein 28; K14573 nucleolar protein 4 (A)	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 28 GN=RBM28 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: RNA-binding protein 28 isoform X1 [Camelus ferus]
ENSG00000106346(USP42)	--	5.13789548	499	4.97602283	481	4.670118554	461	4.944842911	479	6.46490579	593	5.077762286	505	0.967773863	-0.089564914	normal	0.909033462	0.279775215	normal	0.964096669	0.122840065	normal	0.704654063	0.109074312	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11855|0|hsa:84132|USP42; ubiquitin specific peptidase 42 (EC:3.4.19.12); K11855 ubiquitin carboxyl-terminal hydrolase 36/42 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 42 GN=USP42 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 42 [Loxodonta africana]
ENSG00000106348(IMPDH1)	--	40.32237574	1973	37.14974467	1828	40.20887199	1992	32.90470187	1588	34.3045184	1671	29.16097461	1382	0.87185985	-0.343713262	normal	0.977410526	-0.150850311	normal	0.202929604	-0.535260806	normal	0.031295552	-0.341306051	normal	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00088|0|hsa:3614|IMPDH1, IMPD, IMPD1, LCA11, RP10, sWSS2608; IMP (inosine 5'-monophosphate) dehydrogenase 1 (EC:1.1.1.205); K00088 IMP dehydrogenase [EC:1.1.1.205] (A)"	Purine metabolism (ko00230);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	IMP dehydrogenase / GMP reductase domain;; CBS domain;; Nitronate monooxygenase;; FMN-dependent dehydrogenase;; Histidine biosynthesis protein	Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255|HAMAP-Rule:MF_03156} OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: inosine-5'-monophosphate dehydrogenase 1 isoform X4 [Oryctolagus cuniculus]
ENSG00000106351(AGFG2)	--	28.73953179	1384	24.477681	1302	30.62386277	1423	12.161511	566	10.03564151	526	10.72719326	620	2.90E-12	-1.318433098	down	6.33E-12	-1.32651099	down	3.31E-10	-1.204890199	down	6.26E-20	-1.283941418	down	--	--	Molecular Function: GTPase activator activity (GO:0005096);; 	--	--	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf	Arf-GAP domain and FG repeat-containing protein 2 GN=AGFG2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: arf-GAP domain and FG repeat-containing protein 2 [Loxodonta africana]
ENSG00000106355(LSM5)	--	38.49170007	596	36.96868936	686	38.05668242	632	45.180462	799	35.79940034	640	40.72053245	694	0.741136816	0.391177317	normal	0.967290211	-0.121286337	normal	0.967254388	0.126430869	normal	0.580062213	0.134527831	normal	[K]	Transcription	--	"K12624|6.33617e-59|umr:103658954|LSM5; LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae); K12624 U6 snRNA-associated Sm-like protein LSm5 (A)"	RNA degradation (ko03018);; Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm5 GN=LSM5 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: U6 snRNA-associated Sm-like protein LSm5 isoform X1 [Physeter catodon]
ENSG00000106366(SERPINE1)	--	195.8077	12957	197.1139	12948	209.6185	13816	555.851	36471	472.828	31040	256.2719	17004	0	1.462077958	up	1.75E-11	1.239876297	up	0.984149207	0.291213952	normal	0.040187755	1.06620093	normal	--	--	--	"K03982|0|hsa:5054|SERPINE1, PAI, PAI-1, PAI1, PLANH1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; K03982 plasminogen activator inhibitor-1 (A)"	HIF-1 signaling pathway (ko04066);; p53 signaling pathway (ko04115);; Hippo signaling pathway (ko04390);; Complement and coagulation cascades (ko04610);; Chagas disease (American trypanosomiasis) (ko05142)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Plasminogen activator inhibitor 1 (Precursor) GN=SERPINE1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: plasminogen activator inhibitor 1 [Vicugna pacos]
ENSG00000106367(AP1S1)	--	78.670661	1772	70.16037543	1640	74.67546099	1713	86.50703532	1938	84.28185867	1864	74.55455969	1686	0.983301609	0.098276209	normal	0.975730634	0.16313831	normal	0.985063881	-0.031184307	normal	0.743091886	0.077160634	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K12394|1.16606e-97|tup:102477765|AP1S1; adaptor-related protein complex 1, sigma 1 subunit; K12394 AP-1 complex subunit sigma 1/2 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	AP-1 complex subunit sigma-1A GN=AP1S1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	AP-1 complex subunit sigma-1A [Bos taurus] 
ENSG00000106392(C1GALT1)	--	34.30356283	939	42.31590131	1195	31.47328324	998	34.45801269	1100	36.66231065	1077	34.08809885	942	0.959438067	0.197175889	normal	0.967360514	-0.171190595	normal	0.975925142	-0.091461521	normal	0.92907621	-0.027792577	normal	--	--	"Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K00731|0|hsa:56913|C1GALT1, C1GALT, T-synthase; core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 (EC:2.4.1.122); K00731 glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase [EC:2.4.1.122] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	Fringe-like;; Galactosyltransferase	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 GN=C1GALT1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 [Oryctolagus cuniculus] 
ENSG00000106397(PLOD3)	--	22.62828944	1301	21.49991049	1242	23.06861257	1340	28.60245061	1607	22.05802948	1245	22.43624402	1273	0.934531367	0.273625523	normal	0.981499775	-0.017924191	normal	0.980275271	-0.082196836	normal	0.792657495	0.065329099	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13646|0|hsa:8985|PLOD3, LH3; procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 (EC:1.14.11.4); K13646 lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66] (A)"	Lysine degradation (ko00310);; Other types of O-glycan biosynthesis (ko00514)	[O]	"Posttranslational modification, protein turnover, chaperones"	2OG-Fe(II) oxygenase superfamily	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 (Precursor) GN=PLOD3 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: procollagen-lysine,2-oxoglutarate 5-dioxygenase 3 isoform X2 [Mustela putorius furo]"
ENSG00000106399(RPA3)	--	30.430454	521	33.713339	525	32.09742	563	31.949437	563	29.26852	490	33.72679	535	0.969567917	0.080790071	normal	0.96412342	-0.120602541	normal	0.969769121	-0.081662421	normal	0.906136957	-0.040223189	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; 	"K10740|2.27105e-84|hsa:6119|RPA3, REPA3; replication protein A3, 14kDa; K10740 replication factor A3 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	--	--	Replication factor A protein 3	Replication protein A 14 kDa subunit GN=RPA3 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: replication protein A 14 kDa subunit [Ailuropoda melanoleuca] 
ENSG00000106400(ZNHIT1)	--	53.4966	788	48.3441	712	53.5803	825	67.6813	977	70.467	1064	58.7158	870	0.916854645	0.278841651	normal	0.165903326	0.557148403	normal	0.975811869	0.068208074	normal	0.090615916	0.303028441	normal	--	--	--	"K11663|3.56026e-84|tup:102476511|ZNHIT1; zinc finger, HIT-type containing 1; K11663 zinc finger HIT domain-containing protein 1 (A)"	--	[R]	General function prediction only	HIT zinc finger	Zinc finger HIT domain-containing protein 1 GN=ZNHIT1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger HIT domain-containing protein 1 [Loxodonta africana]
ENSG00000106404(CLDN15)	--	6.819353998	229	6.51106136	224	6.346771	200	5.3567826	186	6.664217	222	9.648343	324	0.893002703	-0.328427026	normal	0.965409006	-0.034134129	normal	0.0742952	0.68360312	normal	0.791524454	0.145022906	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|3.31812e-137|hsa:24146|CLDN15; claudin 15; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-15 GN=CLDN15 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: claudin-15 [Camelus ferus] 
ENSG00000106415(GLCCI1)	--	2.06640282	134	1.119048359	83	1.014774806	74	0.963905845	70	1.262173011	90	1.465584496	80	0.031586611	-0.95225661	normal	0.969253236	0.093746538	normal	0.971771798	0.10217463	normal	0.603833701	-0.299220198	normal	--	--	--	--	--	--	--	Protein Family FAM117	Glucocorticoid-induced transcript 1 protein GN=GLCCI1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: glucocorticoid-induced transcript 1 protein, partial [Bubalus bubalis]"
ENSG00000106443(PHF14)	--	10.475094	879	13.31643	1125	12.084836	1008	12.410888	1034	12.66831	1068	12.509202	1050	0.956492642	0.203141206	normal	0.976628854	-0.09630702	normal	0.978997402	0.050527969	normal	0.877071809	0.044379311	normal	--	--	--	--	--	[R]	General function prediction only	PHD-finger;; PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; PHD-finger;; Cucumovirus protein 2B	PHD finger protein 14 GN=PHF14 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: PHD finger protein 14 isoform X2 [Mustela putorius furo] 
ENSG00000106459(NRF1)	--	5.750543839	342	5.237969855	323	5.881562672	298	6.078920076	368	7.170354597	417	4.683316039	287	0.966272343	0.074554264	normal	0.847845911	0.345658951	normal	0.966094131	-0.062231207	normal	0.677256677	0.132764648	normal	--	--	--	K11831|0|nle:100600133|NRF1; nuclear respiratory factor 1; K11831 nuclear respiratory factor 1 (A)	Huntington's disease (ko05016)	--	--	NLS-binding and DNA-binding and dimerisation domains of Nrf1;; Nrf1 activator activation site binding domain	Nuclear respiratory factor 1 GN=NRF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	hypothetical protein PANDA_001295 [Ailuropoda melanoleuca]
ENSG00000106460(TMEM106B)	--	57.82265	2931	47.24174502	2592	52.58580561	2675	49.153727	2843	62.594022	3479	58.98272823	3294	0.988754478	-0.074771332	normal	0.800493564	0.402976807	normal	0.946698463	0.291861276	normal	0.246062083	0.209443303	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1356)	Transmembrane protein 106B GN=TMEM106B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 106B [Equus caballus] 
ENSG00000106462(EZH2)	--	10.23788052	592	10.26919474	590	11.39165224	647	15.14274905	861	13.3699277	753	12.441767	720	0.318713016	0.508483875	normal	0.861812699	0.329758561	normal	0.964723582	0.145616969	normal	0.0767992	0.330152127	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; 	K11430|0|aml:100466177|EZH2; enhancer of zeste homolog 2 (Drosophila); K11430 histone-lysine N-methyltransferase EZH2 [EC:2.1.1.43] (A)	MicroRNAs in cancer (ko05206)	[K]	Transcription	SET domain;; WD repeat binding protein EZH2	Histone-lysine N-methyltransferase EZH2 GN=EZH2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: histone-lysine N-methyltransferase EZH2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000106477(CEP41)	--	6.345995989	511	6.248505593	492	8.35674233	528	7.227845059	523	6.506782639	488	6.1453371	504	0.972067841	0.002647523	normal	0.970357561	-0.033101564	normal	0.969591603	-0.075185202	normal	0.917098815	-0.03638041	normal	--	--	--	K16455|0|ggo:101123879|CEP41; centrosomal protein of 41 kDa isoform 1; K16455 centrosomal protein CEP41 (A)	--	--	--	Rhodanese-like domain	Centrosomal protein of 41 kDa GN=CEP41 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: centrosomal protein of 41 kDa isoform X2 [Tupaia chinensis]
ENSG00000106479(ZNF862)	--	2.147796863	360	1.8680202	374	2.077679861	350	2.099864566	451	2.422934535	471	3.930862724	636	0.898457875	0.29317846	normal	0.883811813	0.310142603	normal	0.000461958	0.850614254	normal	0.053918243	0.503072199	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	--	--	--	--	KRAB box;; hAT family C-terminal dimerisation region	Zinc finger protein 862 GN=ZNF862 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 862 [Ceratotherium simum simum]
ENSG00000106483(SFRP4)	--	2.50242	81	1.7429342	65	1.439667927	58	1.117627	45	0.957017	46	0.974325	35	0.407784172	-0.856706206	normal	0.916790202	-0.506162201	normal	0.831134094	-0.71281989	normal	0.144998006	-0.717331884	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K02185|0|pps:100967992|SFRP4; secreted frizzled-related protein 4; K02185 secreted frizzled-related protein 4 (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Fz domain;; UNC-6/NTR/C345C module	Secreted frizzled-related protein 4 (Precursor) GN=SFRP4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: secreted frizzled-related protein 4 [Vicugna pacos]
ENSG00000106484(MEST)	--	26.85385092	943	22.63162055	807	24.4725004	843	40.72333732	1420	41.9720656	1456	35.83455694	1228	0.1349561	0.558982175	normal	0.000242615	0.828771036	normal	0.210398888	0.533616914	normal	1.13E-05	0.640809852	normal	[R]	General function prediction only	--	--	--	[I]	Lipid transport and metabolism	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Alpha/beta hydrolase of unknown function (DUF1057)	Mesoderm-specific transcript homolog protein GN=MEST OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: mesoderm-specific transcript homolog protein isoform X1 [Tupaia chinensis]
ENSG00000106511(MEOX2)	--	0	0	0	0	0.0435102	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09322|7.92108e-156|hsa:4223|MEOX2, GAX, MOX2; mesenchyme homeobox 2; K09322 homeobox protein MOX (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein MOX-2 GN=MEOX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein MOX-2 [Leptonychotes weddellii]
ENSG00000106524(ANKMY2)	--	9.992134785	486	9.955104	477	10.39755282	489	8.41284813	409	8.007913001	383	7.459659252	360	0.908739013	-0.278725735	normal	0.854358799	-0.336876834	normal	0.608304431	-0.44850591	normal	0.101856811	-0.355445566	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; MYND finger	Ankyrin repeat and MYND domain-containing protein 2 GN=ANKMY2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and MYND domain-containing protein 2 [Tupaia chinensis]
ENSG00000106526(ACTR3C)	--	0	0	0	0	0	0	0.012634995	1	0.024584182	1	0.012581059	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K18584|1.0089e-112|ptr:736054|ACTR3C; ARP3 actin-related protein 3 homolog C (yeast); K18584 actin-related protein 3 (A)	--	[Z]	Cytoskeleton	Actin	Actin-related protein 3B GN=ACTR3B OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: actin-related protein 3B-like isoform X4 [Balaenoptera acutorostrata scammoni] 
ENSG00000106537(TSPAN13)	--	11.8438	303	10.0181	261	10.1963	261	21.2494	553	25.7423	661	16.5578	425	0.001039236	0.833955541	normal	5.70E-10	1.314221864	up	0.036738815	0.69194949	normal	0.000815659	0.968501362	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17356|1.80334e-125|ptr:745167|TSPAN13; tetraspanin 13; K17356 tetraspanin-13/31 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-13 GN=TSPAN13 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetraspanin-13 [Eptesicus fuscus]
ENSG00000106541(AGR2)	--	17.02860633	447	14.35659043	363	17.11494002	433	46.50993602	1098	51.081594	1314	54.11032003	1417	1.09E-10	1.262840325	up	0	1.830215568	up	0	1.698637171	up	3.40E-17	1.602905795	up	--	--	--	--	--	--	--	Thioredoxin-like	Anterior gradient protein 2 homolog (Precursor) GN=AGR2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: anterior gradient protein 2 homolog [Chrysochloris asiatica]
ENSG00000106546(AHR)	--	12.9648	1337	13.6719	1393	12.0093153	1211	12.141562	1257	11.2027072	1155	13.4777882	1395	0.977130055	-0.119705171	normal	0.918975247	-0.291380983	normal	0.964607805	0.195547118	normal	0.775406845	-0.071045284	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09093|0|hsa:196|AHR, bHLHe76; aryl hydrocarbon receptor; K09093 aryl hydrocarbon receptor (A)"	--	[K]	Transcription	PAS fold;; PAS fold;; PAS domain;; PAS domain;; Helix-loop-helix DNA-binding domain	Aryl hydrocarbon receptor (Precursor) GN=AHR OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: aryl hydrocarbon receptor [Galeopterus variegatus]
ENSG00000106554(CHCHD3)	--	48.64670574	1661	54.59610693	1869	53.01140485	1810	54.81020578	1893	50.60000536	1716	48.29620506	1650	0.976959179	0.157653408	normal	0.978518612	-0.144521486	normal	0.978676154	-0.141691073	normal	0.873825493	-0.043654477	normal	--	--	--	"K17563|4.66245e-150|hsa:54927|CHCHD3, MINOS3, PPP1R22; coiled-coil-helix-coiled-coil-helix domain containing 3; K17563 coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial (A)"	--	[K]	Transcription	Protein of unknown function (DUF737)	MICOS complex subunit MIC19 GN=CHCHD3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: coiled-coil-helix-coiled-coil-helix domain-containing protein 3, mitochondrial isoform X3 [Galeopterus variegatus]"
ENSG00000106560(GIMAP2)	--	0.0414088	1	0.285467	7	0.0408443	0	0.327466	8	0.443941	10	0.164919	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTP binding (GO:0005525);; 	--	--	--	--	AIG1 family;; 50S ribosome-binding GTPase	GTPase IMAP family member 2 GN=GIMAP2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: GTPase IMAP family member 2 [Equus przewalskii]
ENSG00000106571(GLI3)	--	0.00637579	1	0	0	0.00629025	0	0.051846991	8	0.529817404	12	0.01890197	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K06230|0|hsa:2737|GLI3, ACLS, GCPS, GLI3-190, GLI3FL, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV; GLI family zinc finger 3; K06230 zinc finger protein GLI3 (A)"	cAMP signaling pathway (ko04024);; Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Transcriptional repressor GLI3R GN=GLI3 OS=Homo sapiens (Human) PE=1 SV=6	K	Transcription	PREDICTED: transcriptional activator GLI3 isoform X1 [Equus caballus] 
ENSG00000106588(PSMA2)	--	88.07025	1881	93.12604	2022	89.86356	1880	99.42009	2182	93.96667	2036	82.97351	1799	0.97497586	0.183179978	normal	0.986633965	-0.01146345	normal	0.984645553	-0.071769894	normal	0.895946735	0.035387654	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: endopeptidase activity (GO:0004175);; Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Cellular Component: proteasome core complex, alpha-subunit complex (GO:0019773);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; "	"K02726|1.59702e-173|umr:103674585|PSMA2; proteasome (prosome, macropain) subunit, alpha type, 2; K02726 20S proteasome subunit alpha 2 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome subunit A N-terminal signature	Proteasome subunit alpha type-2 GN=PSMA2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit alpha type-2 isoform 1 [Canis lupus familiaris]
ENSG00000106591(MRPL32)	--	34.7972	608	34.2247	613	31.1172	555	34.4382	622	31.0745	540	30.7744	548	0.973926468	0.002005982	normal	0.947851642	-0.203818058	normal	0.972546297	-0.026530568	normal	0.798043519	-0.076425405	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Biological Process: translation (GO:0006412);; Cellular Component: large ribosomal subunit (GO:0015934);; 	"K02911|1.04394e-137|hsa:64983|MRPL32, L32mt, MRP-L32, bMRP-59b; mitochondrial ribosomal protein L32; K02911 large subunit ribosomal protein L32 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L32p protein family	"39S ribosomal protein L32, mitochondrial (Precursor) GN=MRPL32 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L32, mitochondrial [Ceratotherium simum simum]"
ENSG00000106603(COA1)	--	63.265432	860	54.793816	743	83.38411	827	53.0978646	748	54.64879459	733	51.131903	726	0.942615377	-0.231686361	normal	0.974775917	-0.040891773	normal	0.955247023	-0.195826736	normal	0.475738105	-0.160061678	normal	--	--	--	"K18173|1.12229e-102|hsa:55744|COA1, C7orf44, MITRAC15; cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae); K18173 cytochrome c oxidase assembly factor 1 (A)"	--	--	--	Cytochrome oxidase complex assembly protein 1	Cytochrome c oxidase assembly factor 1 homolog GN=COA1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PAL_GLEAN10013435 [Pteropus alecto]
ENSG00000106605(BLVRA)	--	59.2326	1033	52.07567139	972	55.879224	1035	48.488048	898	52.521598	937	47.08605608	852	0.945929573	-0.232513861	normal	0.976386496	-0.074216208	normal	0.911109517	-0.288531439	normal	0.313585257	-0.199312018	normal	--	--	Molecular Function: biliverdin reductase activity (GO:0004074);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: heme catabolic process (GO:0042167);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00214|0|hsa:644|BLVRA, BLVR, BVR, BVRA; biliverdin reductase A (EC:1.3.1.24); K00214 biliverdin reductase [EC:1.3.1.24] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	--	--	"Biliverdin reductase, catalytic;; Oxidoreductase family, NAD-binding Rossmann fold"	Biliverdin reductase A (Precursor) GN=BLVRA OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: biliverdin reductase A [Vicugna pacos]
ENSG00000106609(TMEM248)	--	44.03632147	2779	47.57984957	2858	42.86103315	2571	48.16474194	3041	46.80938832	3038	43.76866673	2735	0.987813682	0.099095336	normal	0.988883535	0.066655184	normal	0.987791005	0.080873652	normal	0.726808553	0.081120797	normal	--	--	--	--	--	--	--	Transmembrane 219	Transmembrane protein 248 GN=TMEM248 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein TREES_T100021524 [Tupaia chinensis]
ENSG00000106615(RHEB)	--	73.82510181	1947	71.92725241	1915	72.28886433	1909	72.20137152	1932	63.97401935	1725	87.81545523	2371	0.986124045	-0.041956816	normal	0.974969078	-0.172031366	normal	0.92581489	0.304170505	normal	0.895946735	0.042218364	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07208|7.01547e-133|nle:100598486|RHEB; Ras homolog enriched in brain; K07208 Ras homolog enriched in brain (A)	mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Thyroid hormone signaling pathway (ko04919);; Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	GTP-binding protein Rheb (Precursor) GN=RHEB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GTP-binding protein Rheb-like [Bos mutus]
ENSG00000106617(PRKAG2)	--	25.2981512	980	23.35121996	900	23.50448605	897	19.55730269	745	14.53467901	553	17.15046292	666	0.633870862	-0.425605533	normal	0.006449227	-0.722507093	normal	0.596448952	-0.437018911	normal	0.001298111	-0.521466542	normal	[R]	General function prediction only	--	"K07200|0|ptr:463879|PRKAG2; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; K07200 5'-AMP-activated protein kinase, regulatory gamma subunit (A)"	FoxO signaling pathway (ko04068);; AMPK signaling pathway (ko04152);; Circadian rhythm (ko04710);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Oxytocin signaling pathway (ko04921);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hypertrophic cardiomyopathy (HCM) (ko05410)	[C]	Energy production and conversion	CBS domain	5'-AMP-activated protein kinase subunit gamma-2 GN=PRKAG2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: 5'-AMP-activated protein kinase subunit gamma-2 isoform 1 [Ceratotherium simum simum]
ENSG00000106624(AEBP1)	--	0.036875539	2	0.036298101	2	0.035333551	1	0	0	0.017895448	0	0.054544451	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	Zinc carboxypeptidase;; F5/8 type C domain;; Carboxypeptidase regulatory-like domain	Adipocyte enhancer-binding protein 1 (Precursor) GN=AEBP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: adipocyte enhancer-binding protein 1 [Galeopterus variegatus]
ENSG00000106628(POLD2)	--	78.89094144	2367	83.68916972	2505	82.2297632	2519	83.51371351	2498	83.48984614	2321	76.29463407	2281	0.988079755	0.046851903	normal	0.983553452	-0.131408195	normal	0.981849761	-0.151380569	normal	0.735240536	-0.079381179	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Biological Process: DNA replication (GO:0006260);; 	"K02328|0|pps:100980787|POLD2; polymerase (DNA directed), delta 2, accessory subunit; K02328 DNA polymerase delta subunit 2 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; HTLV-I infection (ko05166)	[L]	"Replication, recombination and repair"	DNA polymerase alpha/epsilon subunit B	DNA polymerase delta subunit 2 GN=POLD2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase delta subunit 2 [Galeopterus variegatus]
ENSG00000106635(BCL7B)	--	21.3922375	730	22.66352	785	21.65086103	701	25.043982	836	27.39053346	891	24.95359032	823	0.962963311	0.164450615	normal	0.96434492	0.16101492	normal	0.945647731	0.22274262	normal	0.395078098	0.18119157	normal	--	--	--	--	--	[R]	General function prediction only	"Putative binding domain;; BCL7, N-terminal conserver region"	B-cell CLL/lymphoma 7 protein family member B GN=BCL7B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: B-cell CLL/lymphoma 7 protein family member B isoform X3 [Canis lupus familiaris]
ENSG00000106636(YKT6)	--	53.13945	2504	51.16579	2471	53.47886	2517	63.95159	3096	63.68681	3008	55.0068	2516	0.953738982	0.275186566	normal	0.959616014	0.262137394	normal	0.988853845	-0.008859412	normal	0.336324248	0.180594409	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K08516|6.64053e-131|ptr:463919|YKT6; YKT6 v-SNARE homolog (S. cerevisiae); K08516 synaptobrevin homolog YKT6 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Regulated-SNARE-like domain;; Synaptobrevin	Synaptobrevin homolog YKT6 (Precursor) GN=YKT6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptobrevin homolog YKT6 [Oryctolagus cuniculus] 
ENSG00000106638(TBL2)	--	18.00789912	841	15.48005914	765	17.52159656	889	18.90927567	911	18.61033248	816	17.84693457	857	0.975066465	0.084364885	normal	0.974151258	0.071545892	normal	0.976560567	-0.061073834	normal	0.926324851	0.029355066	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Transducin beta-like protein 2 GN=TBL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: transducin beta-like protein 2 [Eptesicus fuscus]
ENSG00000106665(CLIP2)	--	11.37898529	1457	10.95319218	1225	10.50882638	1386	11.81830554	1419	11.142585	1300	12.73270802	1563	0.982063571	-0.06888494	normal	0.980360545	0.064226344	normal	0.973079087	0.164929525	normal	0.840701068	0.053117494	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	"K10422|0|hsa:7461|CLIP2, CLIP, CLIP-115, CYLN2, WBSCR3, WBSCR4, WSCR3, WSCR4; CAP-GLY domain containing linker protein 2; K10422 CAP-Gly domain-containing linker protein 2 (A)"	--	[ZR]	Cytoskeleton;; General function prediction only	CAP-Gly domain	CAP-Gly domain-containing linker protein 2 GN=CLIP2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: CAP-Gly domain-containing linker protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000106682(EIF4H)	--	154.1985	6518	152.0686	6608	149.2893	6408	184.4161	7819	185.0133	7788	145.0211	6130	0.984900734	0.23167258	normal	0.986935085	0.215567155	normal	0.993864441	-0.072261078	normal	0.548645989	0.132278842	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Eukaryotic translation initiation factor 4H GN=EIF4H OS=Homo sapiens (Human) PE=1 SV=5	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4H isoform X1 [Tupaia chinensis]
ENSG00000106683(LIMK1)	--	24.71523985	1539	23.25276551	1456	23.68071743	1500	35.65016295	2205	33.58041946	2081	21.55768949	1345	0.401518769	0.487544599	normal	0.398692662	0.493409299	normal	0.972428021	-0.165471496	normal	0.387844549	0.302580639	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K05743|0|ptr:463466|LIMK1; LIM domain kinase 1; K05743 LIM domain kinase 1 [EC:2.7.11.1] (A)	Axon guidance (ko04360);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810)	--	--	Protein tyrosine kinase;; Protein kinase domain;; LIM domain;; PDZ domain (Also known as DHR or GLGF);; Lipopolysaccharide kinase (Kdo/WaaP) family	LIM domain kinase 1 GN=LIMK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: uncharacterized protein LOC102876209 [Elephantulus edwardii]
ENSG00000106686(SPATA6L)	--	0.54050819	18	1.132394199	44	0.560712678	14	1.734415737	61	1.781056775	55	1.841583147	67	0.003903986	1.649286799	up	0.967146976	0.291524591	normal	1.59E-05	2.135155514	up	0.009411632	1.245399213	up	--	--	--	--	--	--	--	Spermatogenesis-assoc protein 6	Spermatogenesis associated 6-like protein GN=SPATA6L OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: spermatogenesis associated 6-like protein [Ceratotherium simum simum]
ENSG00000106688(SLC1A1)	--	2.77530202	173	1.638412089	102	2.105678	131	2.672175275	168	2.5402487	158	1.42392886	89	0.965551059	-0.072489718	normal	0.540255144	0.602697045	normal	0.714733257	-0.558115437	normal	0.996314771	0.00883144	normal	[C]	Energy production and conversion	Molecular Function: symporter activity (GO:0015293);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05612|0|hsa:6505|SLC1A1, DCBXA, EAAC1, EAAT3, SCZD18; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; K05612 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter), member 1 (A)"	Glutamatergic synapse (ko04724);; Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Sodium:dicarboxylate symporter family	Excitatory amino acid transporter 3 GN=SLC1A1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	excitatory amino acid transporter 3 [Canis lupus familiaris] 
ENSG00000106689(LHX2)	--	6.156732974	206	5.50964052	166	6.708855587	246	2.507468247	95	2.274190044	93	4.948574122	79	0.000160117	-1.134691621	down	0.052552819	-0.846851525	normal	6.85E-10	-1.628407494	down	8.71E-06	-1.231905403	down	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09373|0|mcf:102146219|LHX2; LIM homeobox 2; K09373 LIM homeobox protein 2/9 (A)	--	[R]	General function prediction only	LIM domain;; Homeobox domain;; Homeobox KN domain	LIM/homeobox protein Lhx2 GN=LHX2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	LIM/homeobox protein Lhx2 [Pteropus alecto]
ENSG00000106692(FKTN)	--	8.235358	824	7.719971516	849	7.972098155	804	8.118823467	842	7.034672	768	8.028685	872	0.977416165	0.000343	normal	0.962859881	-0.16577417	normal	0.972453759	0.108644919	normal	0.959389613	-0.018294862	normal	--	--	--	--	--	--	--	LicD family	Fukutin GN=FKTN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: fukutin [Equus caballus]
ENSG00000106701(FSD1L)	--	3.20321206	278	3.065256574	263	2.879759187	250	3.337495366	296	2.713304896	223	2.357369419	221	0.966090597	0.059362069	normal	0.926446078	-0.25783348	normal	0.950658166	-0.184982216	normal	0.753701575	-0.118465209	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPRY domain;; Fibronectin type III domain	FSD1-like protein GN=FSD1L OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: FSD1-like protein isoform X2 [Oryctolagus cuniculus]
ENSG00000106714(CNTNAP3)	--	8.577091627	763	9.258327963	837	7.543233553	671	4.718689113	420	6.029792526	536	5.427181907	488	9.42E-05	-0.889672949	normal	0.026044248	-0.662911283	normal	0.505326118	-0.466484864	normal	5.03E-05	-0.674250617	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; F5/8 type C domain;; Concanavalin A-like lectin/glucanases superfamily	Contactin-associated protein-like 3 (Precursor) GN=CNTNAP3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: contactin-associated protein-like 3-like [Odobenus rosmarus divergens]
ENSG00000106723(SPIN1)	--	27.6772	1981	27.4406	1962	25.0511	1761	28.2195	2026	30.0611	2139	29.4952	2106	0.986891909	0.001571825	normal	0.983787915	0.103108753	normal	0.955372264	0.249622817	normal	0.58837887	0.115475263	normal	--	--	Biological Process: gamete generation (GO:0007276);; 	--	--	--	--	Spin/Ssty Family	Spindlin-1 GN=SPIN1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: spindlin-1-like isoform X1 [Tupaia chinensis] 
ENSG00000106733(NMRK1)	--	8.3321785	122	5.690366	81	10.27899891	84	5.212785492	110	6.5148	127	5.417031468	104	0.960567442	-0.177849661	normal	0.616087521	0.618121276	normal	0.946491715	0.295048666	normal	0.649313265	0.227225317	normal	[F]	Nucleotide transport and metabolism	--	K10524|3.89022e-140|ggo:101138986|NMRK1; nicotinamide riboside kinase 1 isoform 1; K10524 nicotinamide/nicotinate riboside kinase [EC:2.7.1.22 2.7.1.173] (A)	Nicotinate and nicotinamide metabolism (ko00760)	[F]	Nucleotide transport and metabolism	AAA domain;; AAA domain	Nicotinamide riboside kinase 1 GN=NMRK1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: nicotinamide riboside kinase 1 isoform X2 [Leptonychotes weddellii]
ENSG00000106771(TMEM245)	--	55.23843	5974	49.09598485	5472	54.71501975	5825	57.26196948	6381	50.373592	5700	53.207688	5975	0.993962001	0.064237047	normal	0.993590195	0.037456988	normal	0.994126044	0.028381946	normal	0.879704748	0.042746483	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function DUF20	Transmembrane protein 245 GN=TMEM245 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 245 [Ceratotherium simum simum]
ENSG00000106772(PRUNE2)	--	0.594057921	52	0.495273357	41	0.780867506	59	0.098687861	8	0.079371779	7	0.364868445	19	1.39E-05	-2.516901761	down	0.000779716	-2.33940413	down	0.00859442	-1.568621901	down	2.43E-05	-2.178484349	down	--	--	Cellular Component: cytoplasm (GO:0005737);; Molecular Function: pyrophosphatase activity (GO:0016462);; 	"K18449|0|hsa:158471|PRUNE2, A214N16.3, BMCC1, BNIPXL, C9orf65, KIAA0367, bA214N16.3; prune homolog 2 (Drosophila); K18449 prune homolog 2 (A)"	--	--	--	Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2;; Divergent CRAL/TRIO domain;; DHHA2 domain;; CRAL/TRIO domain	Protein prune homolog 2 GN=PRUNE2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein prune homolog 2 [Equus przewalskii]
ENSG00000106780(MEGF9)	--	12.8986	1328	15.5949	1607	13.2445	1348	14.6881	1518	15.9959	1645	18.4765	1907	0.972933787	0.161909087	normal	0.984455934	0.012279676	normal	0.37529601	0.491726851	normal	0.286545473	0.222671974	normal	--	--	--	--	--	[W]	Extracellular structures	Laminin EGF-like (Domains III and V)	Multiple epidermal growth factor-like domains protein 9 (Precursor) GN=MEGF9 OS=Homo sapiens (Human) PE=2 SV=3	W	Extracellular structures	PREDICTED: multiple epidermal growth factor-like domains protein 9 [Eptesicus fuscus]
ENSG00000106785(TRIM14)	--	11.122457	832	9.012976058	694	13.338097	922	13.63381	1006	12.81550998	966	9.795460491	739	0.940105526	0.242734491	normal	0.544247884	0.454817461	normal	0.866634725	-0.326883668	normal	0.696304458	0.125569693	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	K12004|0|hsa:9830|TRIM14; tripartite motif containing 14; K12004 tripartite motif-containing protein 14 (A)	--	--	--	SPRY domain;; B-box zinc finger;; SPRY-associated domain	Tripartite motif-containing protein 14 GN=TRIM14 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: tripartite motif-containing protein 14 [Ceratotherium simum simum]
ENSG00000106789(CORO2A)	--	0.739120659	86	0.239156731	28	0.429853143	50	1.48697279	174	1.562322681	182	0.996508569	117	0.007702419	0.973387876	normal	2.22E-16	2.615699699	up	0.003341113	1.193931291	up	0.000551648	1.505963564	up	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K13887|0|hsa:7464|CORO2A, CLIPINB, IR10, WDR2; coronin, actin binding protein, 2A; K13887 coronin-2 (A)"	--	[Z]	Cytoskeleton	"Domain of unknown function (DUF1900);; Domain of unknown function (DUF1899);; WD domain, G-beta repeat"	Coronin-2A GN=CORO2A OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	coronin-2A [Camelus ferus]
ENSG00000106799(TGFBR1)	--	14.38589477	1309	16.2217615	1343	13.56053895	1193	56.77326378	5141	64.08755768	5713	52.03536022	4727	0	1.941513026	up	0	2.06613576	up	0	1.976679783	up	1.53E-48	1.997187569	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K04674|0|mmu:21812|Tgfbr1, ALK5, AU017191, Alk-5, TbetaR-I, TbetaRI; transforming growth factor, beta receptor I (EC:2.7.11.30); K04674 TGF-beta receptor type-1 [EC:2.7.11.30] (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; FoxO signaling pathway (ko04068);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350);; Osteoclast differentiation (ko04380);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Transforming growth factor beta type I GS-motif;; Activin types I and II receptor domain	TGF-beta receptor type-1 (Precursor) GN=TGFBR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TGF-beta receptor type-1 isoform X1 [Bos taurus]
ENSG00000106803(SEC61B)	--	168.62448	711	203.123064	892	174.048	764	197.794324	933	213.4395	874	224.213237	963	0.81099356	0.360513426	normal	0.976599347	-0.050750063	normal	0.869931972	0.32509733	normal	0.307401819	0.205567889	normal	--	--	--	K09481|3.86194e-39|umr:103678507|SEC61B; Sec61 beta subunit; K09481 protein transport protein SEC61 subunit beta (A)	Protein export (ko03060);; Protein processing in endoplasmic reticulum (ko04141);; Phagosome (ko04145)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sec61beta family	Protein transport protein Sec61 subunit beta GN=SEC61B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec61 subunit beta [Mustela putorius furo] 
ENSG00000106804(C5)	--	3.36182	334	3.14454	310	2.79061	271	8.44269	838	11.389835	1125	16.5804	1639	1.54E-10	1.29238993	up	0	1.833141898	up	0	2.581488594	up	0.00047009	1.957477271	up	[R]	General function prediction only	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	"K03994|0|hsa:727|C5, C5D, C5a, C5b, CPAMD4, ECLZB; complement component 5; K03994 complement component 5 (A)"	Complement and coagulation cascades (ko04610);; Prion diseases (ko05020);; Pertussis (ko05133);; Staphylococcus aureus infection (ko05150);; Herpes simplex infection (ko05168);; Systemic lupus erythematosus (ko05322)	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; Alpha-2-macroglobulin family;; Alpha-2-macroglobulin family N-terminal region;; A-macroglobulin receptor;; UNC-6/NTR/C345C module;; MG2 domain;; Anaphylotoxin-like domain	Complement C5 alpha' chain (Precursor) GN=C5 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: complement C5 [Ailuropoda melanoleuca]
ENSG00000106809(OGN)	--	0	0	0.02578072	1	0.025508	0	0.024668888	1	0	0	0.024585486	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08126|3.58869e-175|hsa:4969|OGN, OG, OIF, SLRR3A; osteoglycin; K08126 osteoglycin (osteoinductive factor, mimecan) (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Mimecan (Precursor) GN=OGN OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: mimecan [Galeopterus variegatus]
ENSG00000106819(ASPN)	--	0.0311567	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K08120|0|pps:100978414|ASPN; asporin; K08120 asporin (A)	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat N-terminal domain;; Leucine rich repeat;; Leucine Rich repeat	Asporin (Precursor) GN=ASPN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: asporin [Galeopterus variegatus] 
ENSG00000106823(ECM2)	--	0.19544	5	0.446381643	13	0.571262	13	0.654408328	14	0.187476331	4	1.0007215	25	--	--	--	--	--	--	0.948039515	0.861763253	normal	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08119|0|nle:100599099|ECM2; extracellular matrix protein 2, female organ and adipocyte specific; K08119 extracellular matrix protein 2 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; von Willebrand factor type C domain;; Leucine rich repeat;; Leucine rich repeats (6 copies);; FNIP Repeat	Extracellular matrix protein 2 (Precursor) GN=ECM2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: extracellular matrix protein 2 isoform X1 [Galeopterus variegatus] 
ENSG00000106829(TLE4)	--	15.68951029	938	17.87392472	1124	13.61952089	865	7.000767087	486	10.41568088	620	5.88699552	406	4.04E-06	-0.977197478	normal	7.92E-05	-0.878113081	normal	1.19E-07	-1.096645467	down	1.52E-05	-0.974806844	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[B]	Chromatin structure and dynamics	"Groucho/TLE N-terminal Q-rich domain;; WD domain, G-beta repeat"	Transducin-like enhancer protein 4 GN=TLE4 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: transducin-like enhancer protein 4 [Lipotes vexillifer]
ENSG00000106852(LHX6)	--	0.45761888	14	0.550104825	17	1.63013671	17	0.065464988	4	0.237701318	14	0.129428556	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09375|0|pon:100435907|LHX6; LIM homeobox 6; K09375 LIM homeobox protein 6/8 (A)	--	[R]	General function prediction only	LIM domain;; Homeobox domain	LIM/homeobox protein Lhx6 GN=LHX6 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LIM/homeobox protein Lhx6 isoform 1 [Ceratotherium simum simum]
ENSG00000106853(PTGR1)	--	200.0395058	4608	216.307184	4998	199.0405827	4574	208.2151391	4833	215.1599369	4829	236.1718722	5448	0.99292013	0.037933664	normal	0.992373389	-0.071031129	normal	0.977570194	0.243904917	normal	0.77929442	0.070699813	normal	[R]	General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	K13948|0|pps:100979208|PTGR1; prostaglandin reductase 1; K13948 prostaglandin reductase 1 [EC:1.3.1.74 1.3.1.48] (A)	--	[R]	General function prediction only	Zinc-binding dehydrogenase;; Zinc-binding dehydrogenase	Prostaglandin reductase 1 GN=PTGR1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: prostaglandin reductase 1 [Loxodonta africana]
ENSG00000106868(SUSD1)	--	10.6860008	864	9.043892655	785	9.026516095	769	14.46745065	1389	15.1850029	1630	13.85725311	1218	0.019126429	0.653187197	normal	3.17E-07	1.031272612	up	0.020101019	0.65413626	normal	1.46E-05	0.787686744	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Sushi domain (SCR repeat);; Complement Clr-like EGF-like;; EGF domain;; Fibronectin type III domain	Sushi domain-containing protein 1 (Precursor) GN=SUSD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: sushi domain-containing protein 1, partial [Ceratotherium simum simum]"
ENSG00000106927(AMBP)	--	0.567146089	14	0.45352524	7	0.190251508	4	0.373691089	9	0.504729759	12	0.690225	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; 	--	--	--	--	Kunitz/Bovine pancreatic trypsin inhibitor domain;; Lipocalin / cytosolic fatty-acid binding protein family	Trypstatin (Precursor) GN=AMBP OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein AMBP [Panthera tigris altaica]
ENSG00000106948(AKNA)	--	2.10482015	241	1.545523696	211	2.205560915	241	2.189054121	223	2.42926009	240	2.027899097	206	0.958171952	-0.141881023	normal	0.953758506	0.163267091	normal	0.938423819	-0.233096457	normal	0.873246221	-0.072066268	normal	--	--	--	--	--	--	--	AT-hook-containing transcription factor	AT-hook-containing transcription factor GN=AKNA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	"PREDICTED: AT-hook-containing transcription factor, partial [Galeopterus variegatus]"
ENSG00000106952(TNFSF8)	--	0	0	0	0	0	0	0.0379129	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	"K05471|1.75408e-172|pps:100978140|TNFSF8; tumor necrosis factor (ligand) superfamily, member 8; K05471 tumor necrosis factor ligand superfamily member 8 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNF(Tumour Necrosis Factor) family	Tumor necrosis factor ligand superfamily member 8 GN=TNFSF8 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor ligand superfamily member 8 [Ceratotherium simum simum]
ENSG00000106976(DNM1)	--	42.564975	3320	38.93643458	3062	38.84854	3108	41.28663982	3224	54.970699	4273	43.94956132	3467	0.989811757	-0.073129415	normal	0.632254565	0.459155704	normal	0.985652386	0.149341059	normal	0.392761873	0.187409269	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K01528|0|ssc:100153921|DNM1; dynamin 1; K01528 dynamin GTPase [EC:3.6.5.5] (A)	Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Bacterial invasion of epithelial cells (ko05100)	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Dynamin central region;; Dynamin family;; Dynamin GTPase effector domain;; PH domain	Dynamin-1 GN=DNM1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: dynamin-1 isoform 1 [Orcinus orca] 
ENSG00000106991(ENG)	--	0.291977289	17	0.493877943	27	0.25124801	14	0.11064514	6	0.268168456	15	0.4112479	24	--	--	--	0.944267721	-0.807921089	normal	0.967953457	0.710139276	normal	--	--	--	--	--	--	K06526|0|pps:100994069|ENG; endoglin; K06526 endoglin (A)	--	--	--	Zona pellucida-like domain	Endoglin (Precursor) GN=ENG OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: endoglin [Trichechus manatus latirostris]
ENSG00000106992(AK1)	--	26.26050254	544	22.26225337	478	30.59980959	567	28.02061175	563	24.73186202	591	26.33776792	510	0.972629855	0.018644247	normal	0.905913267	0.283911859	normal	0.958905244	-0.160690791	normal	0.893723959	0.045324037	normal	[F]	Nucleotide transport and metabolism	--	K00939|3.85317e-149|mcf:101867187|uncharacterized LOC101867187; K00939 adenylate kinase [EC:2.7.4.3] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	Adenylate kinase;; AAA domain;; AAA domain;; AAA domain;; Thymidylate kinase;; Zeta toxin	Adenylate kinase isoenzyme 1 {ECO:0000255|HAMAP-Rule:MF_03171} OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: adenylate kinase isoenzyme 1 [Tupaia chinensis]
ENSG00000106993(CDC37L1)	--	5.2342	205	5.282843	256	6.43608	242	7.18988	312	8.64837	370	8.20215	351	0.321755697	0.57159465	normal	0.484275131	0.507448616	normal	0.428056438	0.525431062	normal	0.020709663	0.534502906	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cdc37 Hsp90 binding domain	Hsp90 co-chaperone Cdc37-like 1 GN=CDC37L1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: hsp90 co-chaperone Cdc37-like 1 [Tupaia chinensis]
ENSG00000107014(RLN2)	--	0.89947124	8	0.57031414	5	1.096140063	9	1.185810084	11	0.435488157	3	1.087430287	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05255|5.27288e-133|pps:100982014|RLN2; prorelaxin H2; K05255 relaxin (A)	--	--	--	Insulin/IGF/Relaxin family	Relaxin A chain (Precursor) GN=RLN2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: prorelaxin-like [Physeter catodon]
ENSG00000107018(RLN1)	--	0.0729875	1	0	0	0.0717197	0	0.0725471	1	0.0703386	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	"K05255|6.65611e-121|hsa:6013|RLN1, H1, H1RLX, RLXH1, bA12D24.3.1, bA12D24.3.2; relaxin 1; K05255 relaxin (A)"	--	--	--	Insulin/IGF/Relaxin family	Relaxin A chain (Precursor) GN=RLN1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: prorelaxin-like [Balaenoptera acutorostrata scammoni]
ENSG00000107020(PLGRKT)	--	31.4650881	247	28.69680096	201	22.84663946	208	28.36437193	258	26.45769318	287	22.73624654	230	0.966762683	0.031834009	normal	0.607261303	0.48933291	normal	0.959195078	0.135819471	normal	0.50586514	0.218980777	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2368)	Plasminogen receptor (KT) GN=PLGRKT OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: plasminogen receptor (KT) isoform X4 [Canis lupus familiaris] 
ENSG00000107021(TBC1D13)	--	10.264602	780	9.016633	692	9.986906385	769	12.53330112	951	11.91440068	900	12.225947	930	0.932443634	0.254684039	normal	0.822619294	0.357040485	normal	0.925770823	0.265480261	normal	0.114306336	0.290289349	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 13 GN=TBC1D13 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: TBC1 domain family member 13 isoform X3 [Mustela putorius furo]
ENSG00000107036(RIC1)	--	8.3150712	872	8.984913026	1004	9.0349184	1005	8.664552277	953	8.7096623	882	8.847531	937	0.974562148	0.097152047	normal	0.954671099	-0.208000715	normal	0.974362909	-0.109195779	normal	0.764275791	-0.076817808	normal	--	--	--	--	--	[R]	General function prediction only	RIC1	RAB6A-GEF complex partner protein 1 {ECO:0000312|HGNC:HGNC:17686} OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein RIC1 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000107077(KDM4C)	--	5.359247039	497	4.984311879	473	5.559372	510	6.437859383	605	4.46408631	416	5.710799361	517	0.926623014	0.25214964	normal	0.944376627	-0.205980399	normal	0.972054154	0.011342187	normal	0.926386446	0.033709257	normal	--	--	--	K06709|0|ggo:101132085|KDM4C; lysine-specific demethylase 4C isoform 1; K06709 jumonji domain-containing protein 2 [EC:1.14.11.-] (A)	--	[L]	"Replication, recombination and repair"	"JmjC domain, hydroxylase;; PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; jmjN domain;; PHD-finger;; Lamin-B receptor of TUDOR domain"	Lysine-specific demethylase 4C GN=KDM4C OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: lysine-specific demethylase 4C isoform X1 [Equus caballus]
ENSG00000107099(DOCK8)	--	0.168680286	26	0.232690997	37	0.402055965	16	0.136297462	21	0.183232425	25	0.259594229	41	0.983852991	-0.318003196	normal	0.955149196	-0.559052481	normal	0.389377893	1.271726368	normal	0.923805752	0.118840474	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Dedicator of cytokinesis;; C2 domain in Dock180 and Zizimin proteins;; Domain of unknown function (DUF3398)	Dedicator of cytokinesis protein 8 GN=DOCK8 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 8 isoform X3 [Equus caballus]
ENSG00000107104(KANK1)	--	6.423756738	751	6.258261512	740	5.685614472	716	4.828519259	609	5.79139575	665	5.498728105	676	0.855047266	-0.332446014	normal	0.958619464	-0.175219528	normal	0.971761917	-0.091029877	normal	0.355139816	-0.199533553	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; KN motif;; Ankyrin repeats (many copies);; Ankyrin repeat	KN motif and ankyrin repeat domain-containing protein 1 GN=KANK1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: KN motif and ankyrin repeat domain-containing protein 1 isoform X1 [Equus caballus]
ENSG00000107105(ELAVL2)	--	0.042886544	2	0.037092599	2	0	0	0.104109015	3	0.05956733	2	0.159551465	8	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13208|0|cfa:481565|ELAVL2; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B); K13208 ELAV like protein 2/3/4 (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	ELAV-like protein 2 GN=ELAVL2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ELAV-like protein 2 isoform X1 [Canis lupus familiaris]
ENSG00000107130(NCS1)	--	17.76996802	1593	20.6372294	1703	19.00825851	1701	24.1778368	2255	21.84129347	1995	18.08933067	1579	0.483705696	0.470166085	normal	0.968329003	0.206714013	normal	0.98060548	-0.115556752	normal	0.407761446	0.200001235	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Neuronal calcium sensor 1 GN=NCS1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	neuronal calcium sensor 1 [Bos taurus] 
ENSG00000107140(TESK1)	--	8.6485521	454	9.640466147	502	8.80287416	474	7.66630905	390	6.3365401	328	7.6586621	412	0.926718447	-0.249139635	normal	0.082630725	-0.633039932	normal	0.943811915	-0.209815517	normal	0.097071099	-0.360831091	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08841|0|hsa:7016|TESK1; testis-specific kinase 1 (EC:2.7.12.1); K08841 testis-specific kinase 1 [EC:2.7.12.1] (A)	--	--	--	Protein kinase domain;; Protein tyrosine kinase	Dual specificity testis-specific protein kinase 1 GN=TESK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity testis-specific protein kinase 1 [Panthera tigris altaica]
ENSG00000107147(KCNT1)	--	0	0	0	0	0	0	0	0	0.012928415	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: potassium ion transport (GO:0006813);; Cellular Component: membrane (GO:0016020);; 	"K04946|0|hsa:57582|KCNT1, EIEE14, ENFL5, KCa4.1, SLACK, bA100C15.2; potassium channel, subfamily T, member 1; K04946 potassium channel subfamily T member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Calcium-activated BK potassium channel alpha subunit;; Ion channel	Potassium channel subfamily T member 1 GN=KCNT1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily T member 1 isoform 1 [Ceratotherium simum simum]
ENSG00000107159(CA9)	--	12.99844201	355	7.122349812	197	11.74210276	329	30.84500486	851	14.35122496	390	26.18131203	721	1.54E-09	1.226973824	up	0.00024441	0.958525706	normal	1.29E-07	1.120054417	up	0.05214069	1.133453508	normal	[P]	Inorganic ion transport and metabolism	--	"K01672|0|hsa:768|CA9, CAIX, MN; carbonic anhydrase IX (EC:4.2.1.1); K01672 carbonic anhydrase [EC:4.2.1.1] (A)"	Nitrogen metabolism (ko00910)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase 9 (Precursor) GN=CA9 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carbonic anhydrase 9 [Ceratotherium simum simum]
ENSG00000107164(FUBP3)	--	37.042	1913	39.09899	2103	38.87064	2065	38.99511	2076	40.64121	2184	39.93231	2079	0.98473711	0.087070169	normal	0.986896597	0.03307411	normal	0.987208883	0.001455472	normal	0.88786548	0.038822184	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K13210|0|pon:100438651|FUBP3; far upstream element (FUSE) binding protein 3; K13210 far upstream element-binding protein (A)	--	[A]	RNA processing and modification	KH domain;; KH domain;; KH domain;; KH domain	Far upstream element-binding protein 3 GN=FUBP3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: far upstream element-binding protein 3 [Ceratotherium simum simum]
ENSG00000107165(TYRP1)	--	0.114057543	4	0.334300935	5	0.296296322	6	0.164686094	2	0.168246787	7	0.171610378	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; 	"K00506|0|hsa:7306|TYRP1, CAS2, CATB, GP75, OCA3, TRP, TRP1, TYRP, b-PROTEIN; tyrosinase-related protein 1 (EC:1.14.18.-); K00506 tyrosinase-related protein 1 [EC:1.14.18.-] (A)"	Tyrosine metabolism (ko00350);; Melanogenesis (ko04916)	--	--	Common central domain of tyrosinase	"5,6-dihydroxyindole-2-carboxylic acid oxidase (Precursor) GN=TYRP1 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: 5,6-dihydroxyindole-2-carboxylic acid oxidase [Tupaia chinensis]"
ENSG00000107175(CREB3)	--	26.0663	923	23.3799	849	29.4486	1067	31.4991	1120	34.002	1191	31.4641	1114	0.939879876	0.247888871	normal	0.496736424	0.466206223	normal	0.979553767	0.053822952	normal	0.169433177	0.249911518	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09048|0|hsa:10488|CREB3, LUMAN, LZIP, sLZIP; cAMP responsive element binding protein 3; K09048 cyclic AMP-responsive element-binding protein 3 (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Processed cyclic AMP-responsive element-binding protein 3 GN=CREB3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cyclic AMP-responsive element-binding protein 3-like isoform X2 [Tupaia chinensis]
ENSG00000107185(RGP1)	--	9.59453	1236	10.0432	1324	10.4191	1359	10.8027	1397	8.88403	1136	10.1183	1307	0.974207637	0.145650645	normal	0.947605153	-0.242068007	normal	0.981439206	-0.064504557	normal	0.849360385	-0.0507686	normal	--	--	--	--	--	[S]	Function unknown	Rgp1	RAB6A-GEF complex partner protein 2 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: retrograde Golgi transport protein RGP1 homolog isoform X1 [Galeopterus variegatus]
ENSG00000107186(MPDZ)	--	8.949219126	1269	9.433964	1356	9.071269005	1334	9.541685996	1324	9.305547	1331	9.49668338	1393	0.98217723	0.030342824	normal	0.981710799	-0.048218885	normal	0.982115349	0.054085145	normal	0.976256549	0.011050071	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06095|0|pon:100459044|MPDZ; multiple PDZ domain protein; K06095 multiple PDZ domain protein (A)	Tight junction (ko04530)	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; L27_2	Multiple PDZ domain protein GN=MPDZ OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: multiple PDZ domain protein isoform X4 [Balaenoptera acutorostrata scammoni]
ENSG00000107187(LHX3)	--	0.050195205	2	0.02465816	1	0.02375861	0	0.149583366	6	0	0	0.073607783	3	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K09374|0|mcc:574165|LHX3; LIM homeobox 3; K09374 LIM homeobox protein 3/4 (A)	--	[K]	Transcription	LIM domain;; Homeobox domain	LIM/homeobox protein Lhx3 GN=LHX3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LIM/homeobox protein Lhx3-like isoform 1 [Tursiops truncatus]
ENSG00000107201(DDX58)	--	10.47134722	852	10.8671827	903	11.77868781	947	13.81496497	1142	13.10606193	1078	13.86011256	1142	0.744216734	0.391193869	normal	0.946160037	0.233774019	normal	0.933146975	0.26145415	normal	0.092485882	0.294205274	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K12646|0|ptr:465035|DDX58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; K12646 ATP-dependent RNA helicase DDX58 [EC:3.6.3.14] (A)	NF-kappa B signaling pathway (ko04064);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[R]	General function prediction only	"C-terminal domain of RIG-I;; DEAD/DEAH box helicase;; Type III restriction enzyme, res subunit;; Helicase conserved C-terminal domain"	Probable ATP-dependent RNA helicase DDX58 GN=DDX58 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX58 [Pteropus alecto]
ENSG00000107223(EDF1)	--	209.52755	2150	197.36787	2147	206.03836	2254	230.57402	2484	217.50468	2199	181.23027	1908	0.977966489	0.177378251	normal	0.987250408	0.013089745	normal	0.95768193	-0.248536321	normal	0.971151654	-0.013116222	normal	[K]	Transcription	Molecular Function: sequence-specific DNA binding (GO:0043565);; 	K03627|1.08347e-101|ptr:748763|EDF1; endothelial differentiation-related factor 1; K03627 putative transcription factor (A)	--	[K]	Transcription	Multiprotein bridging factor 1;; Helix-turn-helix	Endothelial differentiation-related factor 1 GN=EDF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: endothelial differentiation-related factor 1 [Camelus bactrianus] 
ENSG00000107242(PIP5K1B)	--	0.020157569	1	0.020301946	1	0.020035297	0	0.020145043	1	0.019439	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; 	"K00889|0|ptr:464513|PIP5K1B; phosphatidylinositol-4-phosphate 5-kinase, type I, beta; K00889 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Phosphatidylinositol-4-phosphate 5-Kinase	Phosphatidylinositol 4-phosphate 5-kinase type-1 beta GN=PIP5K1B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-phosphate 5-kinase type-1 beta [Tupaia chinensis]
ENSG00000107249(GLIS3)	--	7.798103231	995	9.453416968	1144	8.802714259	933	10.8425389	1184	12.21341418	1438	16.0235575	1883	0.953511256	0.219757016	normal	0.904558369	0.308186009	normal	3.90E-07	1.003624256	up	0.122711394	0.532285223	normal	[R]	General function prediction only	--	"K09232|0|hsa:169792|GLIS3, ZNF515; GLIS family zinc finger 3; K09232 zinc finger protein GLIS1/3 (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein GLIS3 GN=GLIS3 OS=Homo sapiens (Human) PE=2 SV=5	R	General function prediction only	PREDICTED: zinc finger protein GLIS3 [Oryctolagus cuniculus]
ENSG00000107262(BAG1)	--	50.571127	862	47.01416643	875	47.67860892	894	74.9374484	1406	85.29930981	1516	64.551534	1269	0.011595228	0.674055277	normal	0.001187808	0.770464578	normal	0.348039328	0.496345688	normal	7.61E-06	0.650311556	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: chaperone binding (GO:0051087);; 	K09555|1.22297e-142|nle:100597191|BAG1; BCL2-associated athanogene; K09555 BCL2-associated athanogene 1 (A)	Protein processing in endoplasmic reticulum (ko04141)	--	--	BAG domain;; Ubiquitin family	BAG family molecular chaperone regulator 1 GN=BAG1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: BAG family molecular chaperone regulator 1 [Lipotes vexillifer]
ENSG00000107263(RAPGEF1)	--	16.2718403	2104	18.801258	2287	15.65533468	2042	15.980035	1889	15.21754731	1810	18.7414203	2374	0.974175085	-0.186200669	normal	0.861926578	-0.358625981	normal	0.971198931	0.208902016	normal	0.676561262	-0.103760033	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K06277|0|pps:100972192|RAPGEF1; Rap guanine nucleotide exchange factor (GEF) 1; K06277 Rap guanine nucleotide exchange factor 1 (A)	Rap1 signaling pathway (ko04015);; Focal adhesion (ko04510);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif	Rap guanine nucleotide exchange factor 1 GN=RAPGEF1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rap guanine nucleotide exchange factor 1 isoform X1 [Equus caballus] 
ENSG00000107281(NPDC1)	--	37.92478765	1591	38.12358388	1586	41.04671763	1709	41.62954123	1507	41.82944394	1446	47.26655785	1761	0.980412191	-0.108978525	normal	0.974800782	-0.154597323	normal	0.985198108	0.034920628	normal	0.763011472	-0.072319313	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[T]	Signal transduction mechanisms	Neural proliferation differentiation control-1 protein (NPDC1)	Neural proliferation differentiation and control protein 1 (Precursor) GN=NPDC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neural proliferation differentiation and control protein 1 [Lipotes vexillifer]
ENSG00000107282(APBA1)	--	0.269706141	35	1.48729349	17	0.112370602	14	0.08475771	11	0.134390308	17	0.708641603	16	0.199328612	-1.571501073	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04531|0|hsa:320|APBA1, D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA; amyloid beta (A4) precursor protein-binding, family A, member 1; K04531 amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) (A)"	--	[R]	General function prediction only	Phosphotyrosine interaction domain (PTB/PID);; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Amyloid beta A4 precursor protein-binding family A member 1 GN=APBA1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: amyloid beta A4 precursor protein-binding family A member 1 isoform X4 [Mustela putorius furo]
ENSG00000107290(SETX)	--	14.20568	2806	12.90010571	2641	13.35335771	2768	14.468805	2903	13.342832	2751	12.1221853	2460	0.98979673	0.018187509	normal	0.988816651	0.037424283	normal	0.979583732	-0.178373629	normal	0.886955568	-0.039477873	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K10706|0|hsa:23064|SETX, ALS4, AOA2, SCAR1, bA479K20.2; senataxin (EC:3.6.1.-); K10706 senataxin [EC:3.6.4.-] (A)"	--	[A]	RNA processing and modification	AAA domain;; AAA domain;; Part of AAA domain;; AAA domain;; UvrD/REP helicase N-terminal domain;; Viral (Superfamily 1) RNA helicase	Probable helicase senataxin GN=SETX OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: probable helicase senataxin [Equus caballus] 
ENSG00000107295(SH3GL2)	--	0	0	0	0	0	0	0	0	0.0417776	1	0.0641753	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	K11247|0|cjc:100403486|SH3GL2; SH3-domain GRB2-like 2; K11247 endophilin-A (A)	Endocytosis (ko04144)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	BAR domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; Bin/amphiphysin/Rvs domain for vesicular trafficking	Endophilin-A1 GN=SH3GL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endophilin-A1 [Ochotona princeps]
ENSG00000107317(PTGDS)	--	0.583002748	6	0.661978694	7	0.366744479	3	0.093814611	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K01830|9.59242e-107|hsa:5730|PTGDS, L-PGDS, LPGDS, PDS, PGD2, PGDS, PGDS2; prostaglandin D2 synthase 21kDa (brain) (EC:5.3.99.2); K01830 prostaglandin-H2 D-isomerase [EC:5.3.99.2] (A)"	Arachidonic acid metabolism (ko00590)	--	--	Lipocalin / cytosolic fatty-acid binding protein family	Prostaglandin-H2 D-isomerase (Precursor) GN=PTGDS OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: prostaglandin-H2 D-isomerase [Galeopterus variegatus]
ENSG00000107331(ABCA2)	--	13.74475374	2192	11.20372679	1810	10.95595479	1792	8.615612068	1369	10.64770206	1693	7.908234217	1268	0.003817976	-0.709322154	normal	0.980879797	-0.117732546	normal	0.307595128	-0.506796278	normal	0.028253909	-0.441614052	normal	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05642|0|pps:100975330|ABCA2; ATP-binding cassette, sub-family A (ABC1), member 2; K05642 ATP-binding cassette, subfamily A (ABC1), member 2 (A)"	ABC transporters (ko02010);; Lysosome (ko04142)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC-2 family transporter protein;; ABC transporter;; AAA domain	ATP-binding cassette sub-family A member 2 GN=ABCA2 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 2 [Equus caballus]
ENSG00000107338(SHB)	--	45.16669	1813	36.21473	1565	46.91811	1964	41.18601	1768	39.30482	1556	34.95746	1492	0.98454224	-0.067035382	normal	0.983812761	-0.029718355	normal	0.735207988	-0.40448033	normal	0.373778807	-0.170971881	normal	--	--	--	--	--	--	--	SH2 domain	SH2 domain-containing adapter protein B GN=SHB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: SH2 domain-containing adapter protein B [Lipotes vexillifer]
ENSG00000107341(UBE2R2)	--	33.96261	2497	31.99713	2388	34.03689	2512	33.28971	2459	36.11653	2647	31.99413	2372	0.988102382	-0.052923534	normal	0.98436269	0.127052355	normal	0.986587936	-0.09096753	normal	0.987290824	-0.005473074	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K02207|2.66678e-149|umr:103667038|UBE2R2; ubiquitin-conjugating enzyme E2R 2; K02207 ubiquitin-conjugating enzyme E2 R [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Herpes simplex infection (ko05168)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 R2 GN=UBE2R2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2R 2 [Elephantulus edwardii]
ENSG00000107362(ABHD17B)	--	16.392247	442	14.4738026	440	15.57078	448	13.886698	421	16.95955987	492	16.82446554	486	0.965528419	-0.100699671	normal	0.96048833	0.139275381	normal	0.965501652	0.108813394	normal	0.883948186	0.052281261	normal	[R]	General function prediction only	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; 	--	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Prolyl oligopeptidase family;; Dienelactone hydrolase family	Alpha/beta hydrolase domain-containing protein 17B (Precursor) GN=ABHD17B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: alpha/beta hydrolase domain-containing protein 17B isoform X1 [Camelus bactrianus] 
ENSG00000107371(EXOSC3)	--	25.33349	581	22.55938	567	25.01255	660	24.6141	651	29.42049	651	20.86442	522	0.965243724	0.132954854	normal	0.956010898	0.177440307	normal	0.835623703	-0.345814543	normal	0.98564369	-0.008808861	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; 	K03681|0|ptr:465105|EXOSC3; exosome component 3; K03681 exosome complex component RRP40 (A)	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	--	Exosome complex component RRP40 GN=EXOSC3 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component RRP40 [Ovis aries] 
ENSG00000107372(ZFAND5)	--	96.99457858	4515	122.0903337	5674	96.28540663	4440	97.28445606	4572	107.2061328	5037	105.3470759	4979	0.992895343	-0.012728543	normal	0.986369063	-0.193173293	normal	0.988502387	0.156954389	normal	0.936208879	-0.025241194	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	A20-like zinc finger;; AN1-like Zinc finger	AN1-type zinc finger protein 5 GN=ZFAND5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: AN1-type zinc finger protein 5 isoform X1 [Panthera tigris altaica]
ENSG00000107404(DVL1)	--	24.4257869	1422	23.912504	1267	24.98486796	1429	28.10017795	1637	22.5202805	1293	18.5540225	988	0.972338166	0.172127159	normal	0.981909736	0.007869895	normal	0.186323035	-0.540023085	normal	0.824543291	-0.094403772	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K02353|0|ggo:101141318|DVL1; segment polarity protein dishevelled homolog DVL-1 isoform 1; K02353 segment polarity protein dishevelled (A)	Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[R]	General function prediction only	"Segment polarity protein dishevelled (Dsh) C terminal;; DIX domain;; Dishevelled specific domain;; PDZ domain (Also known as DHR or GLGF);; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	Segment polarity protein dishevelled homolog DVL-1 GN=DVL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: segment polarity protein dishevelled homolog DVL-1 isoform X1 [Tupaia chinensis]
ENSG00000107438(PDLIM1)	--	133.891	3534	106.388	2797	130.41	3428	119.927	3149	120.447	3166	96.2563	2542	0.980228149	-0.197149677	normal	0.983607664	0.15727448	normal	0.66485573	-0.43946851	normal	0.486942594	-0.161482098	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	PDZ domain (Also known as DHR or GLGF);; LIM domain;; PDZ domain	PDZ and LIM domain protein 1 GN=PDLIM1 OS=Homo sapiens (Human) PE=1 SV=4	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: PDZ and LIM domain protein 1 [Loxodonta africana]
ENSG00000107443(CCNJ)	--	6.001440139	367	5.342317769	328	5.424152663	307	5.036528765	296	6.22702188	381	6.146302876	377	0.858459593	-0.339429259	normal	0.946754539	0.193838791	normal	0.905790575	0.286757626	normal	0.89585148	0.052382594	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	--	--	--	--	"Cyclin, C-terminal domain;; Cyclin, N-terminal domain"	Cyclin-J GN=CCNJ OS=Homo sapiens (Human) PE=2 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-J isoform X1 [Galeopterus variegatus]
ENSG00000107485(GATA3)	--	1.801288497	99	1.859485371	102	2.257483268	128	2.226655888	124	1.936516	107	1.784592194	107	0.941299006	0.289979591	normal	0.968613913	0.046935644	normal	0.945685285	-0.263415818	normal	0.985893701	0.017695507	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K17895|0|hsa:2625|GATA3, HDR, HDRS; GATA binding protein 3; K17895 GATA-binding protein 3 (A)"	Inflammatory bowel disease (IBD) (ko05321)	[K]	Transcription	GATA zinc finger	Trans-acting T-cell-specific transcription factor GATA-3 GN=GATA3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: trans-acting T-cell-specific transcription factor GATA-3 isoform X1 [Eptesicus fuscus]
ENSG00000107518(ATRNL1)	--	1.904229872	70	1.315315471	52	1.875164771	55	2.188795136	80	2.2040518	104	1.98208858	100	0.969754612	0.158555881	normal	0.097115553	0.95849865	normal	0.291810778	0.836899126	normal	0.123965772	0.661558002	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	"Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Lectin C-type domain;; Plexin repeat;; Kelch motif;; CUB domain;; EGF-like domain"	Attractin-like protein 1 (Precursor) GN=ATRNL1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: attractin-like 1 isoform X3 [Canis lupus familiaris]
ENSG00000107521(HPS1)	--	20.31624962	835	22.30570376	895	20.77796953	889	17.3008936	762	16.20265524	667	20.17547604	819	0.96368496	-0.162504297	normal	0.582697308	-0.444753529	normal	0.970657036	-0.12638734	normal	0.213702534	-0.241373427	normal	--	--	--	--	--	--	--	--	Hermansky-Pudlak syndrome 1 protein GN=HPS1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Hermansky-Pudlak syndrome 1 protein [Trichechus manatus latirostris]
ENSG00000107537(PHYH)	--	26.83910598	754	29.90435006	823	31.53505107	836	27.19324145	754	25.69099885	668	31.07085096	863	0.975868044	-0.030769565	normal	0.873280071	-0.321813169	normal	0.97717329	0.037499408	normal	0.692324397	-0.099385217	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	--	K00477|0|pps:100983012|PHYH; phytanoyl-CoA 2-hydroxylase; K00477 phytanoyl-CoA hydroxylase [EC:1.14.11.18] (A)	Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Phytanoyl-CoA dioxygenase (PhyH)	"Phytanoyl-CoA dioxygenase, peroxisomal (Precursor) GN=PHYH OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: phytanoyl-CoA dioxygenase, peroxisomal [Myotis lucifugus]"
ENSG00000107551(RASSF4)	--	3.696908711	187	2.033926733	126	3.428946354	134	1.371150053	92	2.755084918	139	2.124081484	117	0.001526222	-1.041696083	down	0.962927552	0.118875819	normal	0.955829866	-0.201579299	normal	0.33942079	-0.381750083	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K09851|0|hsa:83937|RASSF4, AD037; Ras association (RalGDS/AF-6) domain family member 4; K09851 Ras association domain-containing protein 2/4 (A)"	--	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain	Ras association domain-containing protein 4 GN=RASSF4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ras association domain-containing protein 4 [Tupaia chinensis]
ENSG00000107554(DNMBP)	--	11.94865773	1559	11.24376528	1509	13.26895463	1709	15.82184236	2012	18.03063151	2253	12.9992755	1660	0.881903177	0.336884205	normal	0.16195488	0.556368806	normal	0.984519829	-0.050215509	normal	0.149668522	0.289289431	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	BAR domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; RhoGEF domain	Dynamin-binding protein GN=DNMBP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dynamin-binding protein [Ceratotherium simum simum]
ENSG00000107560(RAB11FIP2)	--	9.211474	865	9.23193	850	9.891160519	943	8.478949	809	9.281719	837	9.18720834	893	0.970169098	-0.127159075	normal	0.976309057	-0.043583633	normal	0.975585091	-0.086746061	normal	0.730012906	-0.086794012	normal	--	--	--	K12484|0|pon:100448703|RAB11FIP2; RAB11 family interacting protein 2 (class I); K12484 Rab11 family-interacting protein 1/2/5 (A)	Endocytosis (ko04144)	--	--	FIP domain;; C2 domain	Rab11 family-interacting protein 2 GN=RAB11FIP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: rab11 family-interacting protein 2 [Equus caballus] 
ENSG00000107562(CXCL12)	--	0	0	0	0	0	0	0.036131	1	0	0	0.06805895	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	K10031|2.37639e-72|mcf:102124268|CXCL12; chemokine (C-X-C motif) ligand 12; K10031 C-X-C motif chemokine 12 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; Leukocyte transendothelial migration (ko04670);; Intestinal immune network for IgA production (ko04672);; Pathways in cancer (ko05200);; Rheumatoid arthritis (ko05323)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	SDF-1-alpha(3-67) (Precursor) GN=CXCL12 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: stromal cell-derived factor 1 [Galeopterus variegatus]
ENSG00000107566(ERLIN1)	--	68.89284972	3087	66.75055552	2949	71.00181837	3200	71.17613085	3198	62.17251055	2921	61.98253347	2738	0.990494966	0.020122353	normal	0.989530024	-0.035171899	normal	0.970737803	-0.233121668	normal	0.726808553	-0.082003498	normal	--	--	--	--	--	[R]	General function prediction only	SPFH domain / Band 7 family	Erlin-1 GN=ERLIN1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: erlin-1 [Oryctolagus cuniculus]
ENSG00000107581(EIF3A)	--	73.78928689	9631	83.65439422	11170	75.39642802	9947	82.8183909	11001	87.57596808	11371	75.03021102	9834	0.993706228	0.161020854	normal	0.99646815	0.004302814	normal	0.996158841	-0.024770776	normal	0.878142483	0.045253671	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03254|0|nle:100581640|EIF6, EIF3A; eukaryotic translation initiation factor 6; K03254 translation initiation factor 3 subunit A (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	PCI domain	Eukaryotic translation initiation factor 3 subunit A {ECO:0000255|HAMAP-Rule:MF_03000} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	EIF6 protein [Bos taurus]
ENSG00000107593(PKD2L1)	--	0	0	0	0	0	0	0.0169813	1	0.0166305	0	0.2956267	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04990|0|ptr:466255|PKD2L1; polycystic kidney disease 2-like 1; K04990 polycystin 2L1 (A)	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Polycystin cation channel;; Ion transport protein	Polycystic kidney disease 2-like 1 protein GN=PKD2L1 OS=Homo sapiens (Human) PE=1 SV=1	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: polycystic kidney disease 2-like 1 protein isoform X2 [Mustela putorius furo] 
ENSG00000107611(CUBN)	--	0.0390763	9	0.0173841	4	0.0302504	6	0.0173669	4	0.0253098	5	0.0603427	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K14616|0|hsa:8029|CUBN, IFCR, MGA1, gp280; cubilin (intrinsic factor-cobalamin receptor); K14616 cubilin (A)"	Vitamin digestion and absorption (ko04977)	[H]	Coenzyme transport and metabolism	CUB domain;; EGF-like domain;; Calcium-binding EGF domain;; EGF domain;; Coagulation Factor Xa inhibitory site;; CUB-like domain	Cubilin (Precursor) GN=CUBN OS=Homo sapiens (Human) PE=1 SV=5	H	Coenzyme transport and metabolism	PREDICTED: cubilin [Odobenus rosmarus divergens]
ENSG00000107614(TRDMT1)	--	2.637609758	138	1.731919976	110	1.701175286	96	2.592356904	146	3.194183486	191	2.190894844	148	0.967474928	0.0499274	normal	0.096698222	0.76655072	normal	0.556967709	0.608422907	normal	0.173404601	0.474179165	normal	[L]	"Replication, recombination and repair"	--	"K15336|0|hsa:1787|TRDMT1, DMNT2, DNMT2, MHSAIIP, PUMET, RNMT1; tRNA aspartic acid methyltransferase 1 (EC:2.1.1.204); K15336 tRNA (cytosine38-C5)-methyltransferase [EC:2.1.1.204] (A)"	--	[K]	Transcription	C-5 cytosine-specific DNA methylase	tRNA (cytosine(38)-C(5))-methyltransferase GN=TRDMT1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (cytosine(38)-C(5))-methyltransferase isoform X2 [Felis catus]
ENSG00000107625(DDX50)	--	14.40868765	706	13.21566	651	14.938619	728	18.06314741	897	16.13828	789	15.95894	783	0.881367926	0.314000117	normal	0.928890083	0.255401583	normal	0.972288075	0.096588909	normal	0.271778041	0.222384805	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Molecular Function: hydrolase activity (GO:0016787);; 	K13183|0|pon:100436047|DDX50; DEAD (Asp-Glu-Ala-Asp) box polypeptide 50; K13183 ATP-dependent RNA helicase DDX50 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; GUCT (NUC152) domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	ATP-dependent RNA helicase DDX50 GN=DDX50 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX50 isoform 1 [Trichechus manatus latirostris]
ENSG00000107643(MAPK8)	--	12.41287179	627	14.67771428	685	12.75472364	618	11.44725492	597	13.404103	603	12.25165097	577	0.9691255	-0.101312307	normal	0.949063054	-0.204890035	normal	0.968358792	-0.10705578	normal	0.57391977	-0.140556088	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K04440|0|hsa:5599|MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c; mitogen-activated protein kinase 8 (EC:2.7.11.24); K04440 c-Jun N-terminal kinase [EC:2.7.11.24] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Protein processing in endoplasmic reticulum (ko04141);; Wnt signaling pathway (ko04310);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Shigellosis (ko05131);; Salmonella infection (ko05132);; Pertussis (ko05133);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Mitogen-activated protein kinase 8 GN=MAPK8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 8 isoform X1 [Myotis brandtii] 
ENSG00000107651(SEC23IP)	--	26.51123922	2039	24.98367557	2160	28.29717889	2051	27.46342787	2115	29.84475937	2192	24.87257537	1938	0.987098185	0.021947387	normal	0.987305205	-0.000209926	normal	0.984607322	-0.089982098	normal	0.941666128	-0.022613291	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	DDHD domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	SEC23-interacting protein GN=SEC23IP OS=Homo sapiens (Human) PE=1 SV=1	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: SEC23-interacting protein [Equus caballus]
ENSG00000107669(ATE1)	--	12.01104382	823	11.90043138	823	11.26953626	770	12.72362434	906	11.61268757	882	10.55247298	809	0.9728618	0.107594873	normal	0.974672029	0.078320634	normal	0.975246102	0.062869343	normal	0.748610372	0.082594888	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: arginyltransferase activity (GO:0004057);; Biological Process: protein arginylation (GO:0016598);; 	K00685|0|hsa:11101|ATE1; arginyltransferase 1 (EC:2.3.2.8); K00685 arginine-tRNA-protein transferase [EC:2.3.2.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Arginine-tRNA-protein transferase, C terminus;; Arginine-tRNA-protein transferase, N terminus"	Arginyl-tRNA--protein transferase 1 GN=ATE1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: arginyl-tRNA--protein transferase 1 isoform X2 [Pteropus alecto]
ENSG00000107672(NSMCE4A)	--	24.70827149	604	26.06891802	640	24.27851522	594	25.82095986	639	28.60154	697	25.47911566	626	0.972941775	0.050310691	normal	0.969629421	0.101430486	normal	0.971947668	0.06724151	normal	0.801177058	0.072897936	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Nse4 C-terminal;; Binding domain of Nse4/EID3 to Nse3-MAGE	Non-structural maintenance of chromosomes element 4 homolog A GN=NSMCE4A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: non-structural maintenance of chromosomes element 4 homolog A isoform X1 [Tupaia chinensis] 
ENSG00000107679(PLEKHA1)	--	14.36973851	856	17.32425574	974	15.0658107	817	20.69980411	1136	18.14150964	1016	19.76411189	994	0.780440499	0.376859041	normal	0.978446547	0.039420239	normal	0.921294965	0.274157563	normal	0.228165793	0.227312014	normal	--	--	--	--	--	--	--	PH domain;; Pleckstrin homology domain;; Pleckstrin homology domain;; Meiotic cell cortex C-terminal pleckstrin homology;; Pleckstrin homology domain	Pleckstrin homology domain-containing family A member 1 GN=PLEKHA1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family A member 1 [Tupaia chinensis]
ENSG00000107719(PALD1)	--	5.287127	460	4.276476802	374	4.938384031	465	5.097421304	455	4.348257532	380	2.6415212	214	0.969908794	-0.046443602	normal	0.968409291	0.001528459	normal	1.18E-06	-1.122393862	down	0.472327916	-0.331373866	normal	--	--	--	--	--	--	--	Inositol hexakisphosphate	Paladin GN=PALD1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: paladin [Pteropus alecto]
ENSG00000107731(UNC5B)	--	0.084604417	11	0.04557762	6	0.044722409	5	0.131545992	17	0.2231451	30	0.10768798	15	--	--	--	0.058992064	2.049835642	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K07521|0|ggo:101145005|UNC5B; netrin receptor UNC5B; K07521 netrin receptor unc-5 (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	ZU5 domain;; Immunoglobulin I-set domain;; Death domain;; Immunoglobulin domain;; Thrombospondin type 1 domain	Netrin receptor UNC5B (Precursor) GN=UNC5B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: netrin receptor UNC5B isoformX1 [Canis lupus familiaris]
ENSG00000107736(CDH23)	--	1.451740859	90	1.687449625	92	1.374017838	92	0.609822029	27	0.781454454	31	1.141289716	59	3.89E-05	-1.711283139	down	0.000255734	-1.544925873	down	0.735792593	-0.636048608	normal	0.001886141	-1.246484892	down	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K06813|0|hsa:100653137|cadherin-23-like; K06813 cadherin 23 (A)	--	[S]	Function unknown	Cadherin domain;; Cadherin-like;; Cadherin prodomain like	Cadherin-23 (Precursor) GN=CDH23 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cadherin-23 [Tupaia chinensis]
ENSG00000107738(VSIR)	--	18.89631	826	16.729915	851	18.78043	902	12.03436805	453	10.62404503	527	16.39501	776	6.58E-05	-0.895178358	normal	0.008955563	-0.711160511	normal	0.94650831	-0.224955185	normal	0.025752459	-0.573966596	normal	--	--	--	--	--	--	--	Immunoglobulin V-set domain	Platelet receptor Gi24 (Precursor) GN=C10orf54 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: platelet receptor Gi24 [Tupaia chinensis]
ENSG00000107742(SPOCK2)	--	0.310416195	34	0.338255039	38	0.45242092	36	0.337876757	24	0.187382235	20	0.165840212	14	0.968035971	-0.505979479	normal	0.842902353	-0.897403895	normal	0.509245699	-1.281671927	normal	0.134642319	-0.919669937	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	"K08136|0|ptr:450518|SPOCK2; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2; K08136 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) (A)"	--	[R]	General function prediction only	Secreted protein acidic and rich in cysteine Ca binding region;; Thyroglobulin type-1 repeat;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Testican-2 (Precursor) GN=SPOCK2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: testican-2 [Capra hircus]
ENSG00000107745(MICU1)	--	31.92201037	1562	37.32695509	1757	33.57471594	1567	36.51463008	1801	35.81059244	1720	42.66041466	2107	0.973473919	0.174411603	normal	0.984405608	-0.052086871	normal	0.694168427	0.418544126	normal	0.332467214	0.183093382	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[P]	Inorganic ion transport and metabolism	EF-hand domain;; EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF hand;; Cytoskeletal-regulatory complex EF hand	"Calcium uptake protein 1, mitochondrial GN=MICU1 OS=Homo sapiens (Human) PE=1 SV=1"	P	Inorganic ion transport and metabolism	"PREDICTED: calcium uptake protein 1, mitochondrial isoform X2 [Tupaia chinensis]"
ENSG00000107758(PPP3CB)	--	17.44412	688	17.464603	676	18.900411	725	22.53302	941	23.62085	977	18.756588	764	0.653998187	0.420148795	normal	0.328861973	0.508956766	normal	0.974296168	0.067163714	normal	0.056788309	0.338890567	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K04348|0|hsa:5532|PPP3CB, CALNA2, CALNB, CNA2, PP2Bbeta; protein phosphatase 3, catalytic subunit, beta isozyme (EC:3.1.3.16); K04348 serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Oocyte meiosis (ko04114);; Apoptosis (ko04210);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Oxytocin signaling pathway (ko04921);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; HTLV-I infection (ko05166)	[R]	General function prediction only	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform GN=PPP3CB OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X5 [Canis lupus familiaris]
ENSG00000107771(CCSER2)	--	8.296255948	912	11.9221713	1127	9.840272355	1005	8.850496	978	7.815744293	891	9.227755622	1118	0.976966557	0.069854726	normal	0.823624086	-0.359872239	normal	0.971152234	0.145225965	normal	0.867818769	-0.048174622	normal	--	--	--	--	--	--	--	--	Serine-rich coiled-coil domain-containing protein 2 GN=CCSER2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: serine-rich coiled-coil domain-containing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000107779(BMPR1A)	--	10.65384044	1313	14.00045767	1337	17.14030232	1210	11.02418002	1193	10.517825	1217	9.643436	1194	0.969679364	-0.168897683	normal	0.971799511	-0.156910741	normal	0.981442736	-0.027461102	normal	0.581700652	-0.120337984	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K04673|0|hsa:657|BMPR1A, 10q23del, ACVRLK3, ALK3, CD292, SKR5; bone morphogenetic protein receptor, type IA (EC:2.7.11.30); K04673 bone morphogenetic protein receptor type-1A [EC:2.7.11.30] (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Transforming growth factor beta type I GS-motif;; Activin types I and II receptor domain	Bone morphogenetic protein receptor type-1A (Precursor) GN=BMPR1A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein receptor type-1A [Pteropus alecto]
ENSG00000107789(MINPP1)	--	30.96931635	1127	27.78630602	1012	34.54317941	1246	24.64004636	901	24.291159	884	28.781518	1049	0.830013432	-0.353180936	normal	0.95204992	-0.216171624	normal	0.938537756	-0.256241437	normal	0.116930787	-0.276768582	normal	--	--	Molecular Function: acid phosphatase activity (GO:0003993);; 	"K03103|0|ggo:101144263|MINPP1; multiple inositol polyphosphate phosphatase 1 isoform 1; K03103 multiple inositol-polyphosphate phosphatase / 2,3-bisphosphoglycerate 3-phosphatase [EC:3.1.3.62 3.1.3.80] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Inositol phosphate metabolism (ko00562)	[R]	General function prediction only	Histidine phosphatase superfamily (branch 2)	Multiple inositol polyphosphate phosphatase 1 (Precursor) GN=MINPP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: multiple inositol polyphosphate phosphatase 1 isoform X1 [Galeopterus variegatus]
ENSG00000107796(ACTA2)	--	13.25009	379	15.24392	413	15.25805016	421	21.55601	562	22.85567252	628	26.50851	800	0.280217463	0.535746252	normal	0.15071032	0.581457931	normal	4.37E-05	0.915462556	normal	0.004614864	0.694153469	normal	[Z]	Cytoskeleton	--	"K12313|0|umr:103661931|ACTA2; actin, alpha 2, smooth muscle, aorta; K12313 actin, aortic smooth muscle (A)"	Vascular smooth muscle contraction (ko04270)	[Z]	Cytoskeleton	Actin	"Actin, aortic smooth muscle (Precursor) GN=ACTA2 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: actin, aortic smooth muscle isoform X2 [Equus caballus] "
ENSG00000107798(LIPA)	--	61.75303985	2312	60.67662091	2227	59.30738334	2189	58.32365877	2197	54.77995655	2059	71.79872426	2683	0.985052571	-0.104367629	normal	0.981880406	-0.134489274	normal	0.944072069	0.285105456	normal	0.940283296	0.023869138	normal	[R]	General function prediction only	Biological Process: lipid metabolic process (GO:0006629);; 	"K01052|0|ptr:466150|LIPA; lipase A, lysosomal acid, cholesterol esterase; K01052 lysosomal acid lipase/cholesteryl ester hydrolase [EC:3.1.1.13] (A)"	Steroid biosynthesis (ko00100);; Lysosome (ko04142)	[I]	Lipid transport and metabolism	alpha/beta hydrolase fold;; Partial alpha/beta-hydrolase lipase region;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family	Lysosomal acid lipase/cholesteryl ester hydrolase (Precursor) GN=LIPA OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: lysosomal acid lipase/cholesteryl ester hydrolase [Galeopterus variegatus]
ENSG00000107807(TLX1)	--	0.03284733	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09340|2.54069e-142|pps:100975047|TLX1; T-cell leukemia homeobox 1; K09340 T-cell leukemia homeobox protein 1 (A)	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	Homeobox domain	T-cell leukemia homeobox protein 1 GN=TLX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: T-cell leukemia homeobox protein 1 [Oryctolagus cuniculus]
ENSG00000107815(TWNK)	--	12.745267	948	13.19483747	1017	12.8791342	998	14.2350875	1074	15.11339004	1112	13.584594	1032	0.969714475	0.148975829	normal	0.975276192	0.107257991	normal	0.97919646	0.03998023	normal	0.680962758	0.097842287	normal	--	--	Molecular Function: DNA helicase activity (GO:0003678);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication (GO:0006260);; 	"K17680|0|pps:100972543|chromosome unknown open reading frame, human C10orf2; K17680 twinkle protein [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	AAA domain;; KaiC;; AAA domain;; DnaB-like helicase C terminal domain	"Twinkle protein, mitochondrial (Precursor) GN=PEO1 OS=Homo sapiens (Human) PE=1 SV=1"	L	"Replication, recombination and repair"	"PREDICTED: twinkle protein, mitochondrial isoform X1 [Mustela putorius furo] "
ENSG00000107816(LZTS2)	--	27.05497988	1635	29.42498713	1825	26.20989895	1739	25.46799975	1424	28.9993275	1610	25.9773555	1601	0.957323771	-0.229941978	normal	0.968065982	-0.202083904	normal	0.97973657	-0.127460508	normal	0.319634602	-0.186481694	normal	--	--	--	--	--	--	--	Fez1	Leucine zipper putative tumor suppressor 2 {ECO:0000255|HAMAP-Rule:MF_03026} OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leucine zipper putative tumor suppressor 2 [Galeopterus variegatus] 
ENSG00000107819(SFXN3)	--	16.3301076	927	14.761393	847	16.0410698	916	27.1200024	1531	21.1411609	1189	23.475976	1334	0.007096963	0.69209962	normal	0.492707434	0.467181197	normal	0.209162318	0.533313951	normal	0.000119934	0.570096733	normal	--	--	Biological Process: ion transport (GO:0006811);; Molecular Function: ion transmembrane transporter activity (GO:0015075);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Tricarboxylate carrier	Sideroflexin-3 GN=SFXN3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sideroflexin-3 isoform X1 [Pteropus alecto]
ENSG00000107821(KAZALD1)	--	1.789739849	127	1.746321758	111	1.432104113	108	1.0787118	65	1.28062576	91	1.504198136	105	0.028729378	-0.980252464	normal	0.939380265	-0.303473097	normal	0.969702567	-0.04824821	normal	0.312115942	-0.426609915	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Immunoglobulin I-set domain;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Immunoglobulin domain;; Immunoglobulin domain;; Insulin-like growth factor binding protein	Kazal-type serine protease inhibitor domain-containing protein 1 (Precursor) GN=KAZALD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: kazal-type serine protease inhibitor domain-containing protein 1 [Trichechus manatus latirostris]
ENSG00000107829(FBXW4)	--	13.1314	631	13.6362	693	12.2416	619	13.8952	678	16.2847	776	20.416	985	0.9723013	0.072642354	normal	0.96579385	0.141482863	normal	0.020371322	0.660602257	normal	0.274826725	0.307799786	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10262|0|cjc:100391034|FBXW4; F-box and WD repeat domain containing 4; K10262 F-box and WD-40 domain protein 4 (A)	--	--	--	"WD domain, G-beta repeat;; F-box-like"	F-box/WD repeat-containing protein 4 GN=FBXW4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: F-box/WD repeat-containing protein 4 [Sus scrofa]
ENSG00000107831(FGF8)	--	0.080854849	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|9.25234e-161|ggo:101126805|FGF8; fibroblast growth factor 8 isoform 1; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 8 (Precursor) GN=FGF8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	fibroblast growth factor 8 precursor [Bos taurus] 
ENSG00000107833(NPM3)	--	46.64606207	613	34.42052253	468	45.59916249	626	47.50332053	648	40.22935058	526	35.5378428	469	0.973156269	0.049154644	normal	0.959916379	0.146680445	normal	0.659560517	-0.423679435	normal	0.844816195	-0.077021285	normal	--	--	--	K11278|1.65942e-101|nle:100585774|NPM3; nucleophosmin/nucleoplasmin 3; K11278 nucleophosmin 3 (A)	--	--	--	Nucleoplasmin	Nucleoplasmin-3 GN=NPM3 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: nucleoplasmin-3 [Ailuropoda melanoleuca] 
ENSG00000107854(TNKS2)	--	18.3694	1897	18.6698	1934	19.3928	1978	19.7127	2042	19.2536	1983	20.202	2082	0.985166958	0.07537208	normal	0.986278919	0.014659005	normal	0.985879686	0.06558732	normal	0.843804337	0.051083926	normal	[R]	General function prediction only	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; Molecular Function: protein binding (GO:0005515);; 	"K10799|0|ptr:100609110|TNKS2; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; K10799 tankyrase [EC:2.4.2.30] (A)"	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Poly(ADP-ribose) polymerase catalytic domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Shigella flexneri OspC protein	Tankyrase-2 GN=TNKS2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: tankyrase-2 [Elephantulus edwardii]
ENSG00000107859(PITX3)	--	0.338816854	6	0.0547008	1	0	0	0.220150764	4	0.37641508	6	0.067094564	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K09357|4.18786e-152|mcf:102119181|PITX3; paired-like homeodomain 3; K09357 paired-like homeodomain transcription factor 3 (A)	--	[K]	Transcription	Homeobox domain;; OAR domain	Pituitary homeobox 3 GN=PITX3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: pituitary homeobox 3 [Eptesicus fuscus]
ENSG00000107862(GBF1)	--	16.82478	2308	16.79345132	2293	18.623279	2546	20.12168504	2724	19.34630702	2630	20.40942728	2792	0.973673955	0.208123578	normal	0.978833899	0.176291258	normal	0.985440776	0.124704324	normal	0.383245793	0.167808268	normal	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	K18443|0|ptr:466190|GBF1; golgi brefeldin A resistant guanine nucleotide exchange factor 1; K18443 golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; Guanine nucleotide exchange factor in Golgi transport N-terminal	Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 GN=GBF1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 isoform X1 [Sus scrofa]
ENSG00000107863(ARHGAP21)	--	13.35817928	2157	13.18408308	2160	14.051662	2201	16.25728407	2531	15.10440111	2404	16.34663275	2592	0.974205818	0.199717638	normal	0.982765432	0.132890804	normal	0.967998616	0.227470959	normal	0.31673583	0.186538812	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[R]	General function prediction only	RhoGAP domain;; PH domain;; Pleckstrin homology domain;; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Rho GTPase-activating protein 21 GN=ARHGAP21 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 21 [Ceratotherium simum simum]
ENSG00000107864(CPEB3)	--	0.385747637	32	0.276308711	29	0.438692606	36	0.514396999	50	0.477762013	41	0.3619201	33	0.92759359	0.590196426	normal	0.96253071	0.457975074	normal	0.982219326	-0.128195789	normal	0.653176852	0.332159546	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K02602|0|bta:537016|CPEB3; cytoplasmic polyadenylation element binding protein 3; K02602 cytoplasmic polyadenylation element-binding protein (A)	Oocyte meiosis (ko04114);; Dorso-ventral axis formation (ko04320);; Progesterone-mediated oocyte maturation (ko04914)	[J]	"Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Cytoplasmic polyadenylation element-binding protein 3 GN=CPEB3 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: cytoplasmic polyadenylation element-binding protein 3 isoform 1 [Trichechus manatus latirostris]
ENSG00000107872(FBXL15)	--	10.5353792	219	7.7090537	160	9.1855197	197	11.5217479	241	11.18334946	241	9.1366173	205	0.962287754	0.106557237	normal	0.447488089	0.565154473	normal	0.96612264	0.048769814	normal	0.501281228	0.232749836	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10281|0|hsa:79176|FBXL15, FBXO37, Fbl15, JET, PSD; F-box and leucine-rich repeat protein 15; K10281 F-box and leucine-rich repeat protein 15 (A)"	--	[R]	General function prediction only	Leucine Rich repeat;; F-box domain	F-box/LRR-repeat protein 15 GN=FBXL15 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: F-box/LRR-repeat protein 15 [Equus caballus] 
ENSG00000107874(CUEDC2)	--	36.1526	830	33.1299	782	35.5941	848	39.5531	928	40.3154	915	35.675	829	0.970461966	0.129953631	normal	0.953680956	0.204810119	normal	0.976913777	-0.040909815	normal	0.692157708	0.097861807	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CUE domain	CUE domain-containing protein 2 GN=CUEDC2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: CUE domain-containing protein 2 [Felis catus] 
ENSG00000107882(SUFU)	--	4.999051579	437	4.5063725	394	5.45225	423	5.97409087	527	6.120081751	519	4.360411472	381	0.932503619	0.238572753	normal	0.794842058	0.374855234	normal	0.956635172	-0.158560503	normal	0.539406706	0.164447012	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06229|0|ptr:450699|SUFU; suppressor of fused homolog (Drosophila); K06229 suppressor of fused (A)	Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	--	--	Suppressor of Fused Gli/Ci N terminal binding domain;; Suppressor of fused protein (SUFU)	Suppressor of fused homolog GN=SUFU OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: suppressor of fused homolog isoform X2 [Physeter catodon] 
ENSG00000107890(ANKRD26)	--	3.891202772	549	3.91423723	581	4.28743881	623	4.326292045	635	3.789151033	558	4.193874834	613	0.955759373	0.178653004	normal	0.969605495	-0.079488456	normal	0.973660716	-0.0315593	normal	0.955958996	0.021787239	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CCDC144C protein coiled-coil region;; Domain of unknown function (DUF3496);; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Putative binding domain	Ankyrin repeat domain-containing protein 26 GN=ANKRD26 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26 isoform X4 [Loxodonta africana]
ENSG00000107897(ACBD5)	--	17.879509	1222	19.13601486	1276	19.587622	1261	19.711823	1386	17.35787278	1215	21.9890673	1519	0.973340138	0.150672751	normal	0.97859873	-0.091986833	normal	0.941559395	0.259977693	normal	0.617173481	0.111328773	normal	[I]	Lipid transport and metabolism	Molecular Function: fatty-acyl-CoA binding (GO:0000062);; 	--	--	[I]	Lipid transport and metabolism	Acyl CoA binding protein	Acyl-CoA-binding domain-containing protein 5 GN=ACBD5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: acyl-CoA-binding domain-containing protein 5 [Ceratotherium simum simum]
ENSG00000107902(LHPP)	--	11.92306202	252	11.52638461	224	8.881907	195	6.206009576	99	6.404283406	144	5.424479775	92	2.46E-07	-1.364977527	down	0.230148326	-0.653308429	normal	0.000663372	-1.079584157	down	0.000124261	-1.023629359	down	[G]	Carbohydrate transport and metabolism	--	K11725|6.88791e-175|pon:100448223|LHPP; phospholysine phosphohistidine inorganic pyrophosphate phosphatase; K11725 phospholysine phosphohistidine inorganic pyrophosphate phosphatase [EC:3.6.1.1 3.1.3.-] (A)	Oxidative phosphorylation (ko00190)	[R]	General function prediction only	Haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase	Phospholysine phosphohistidine inorganic pyrophosphate phosphatase GN=LHPP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	phospholysine phosphohistidine inorganic pyrophosphate phosphatase [Bos taurus] 
ENSG00000107929(LARP4B)	--	22.30257355	2078	23.8727743	2167	22.48480399	2018	24.15874494	2168	27.23920002	2452	23.43028609	2216	0.987186234	0.030314895	normal	0.98049173	0.156730395	normal	0.982726174	0.126649664	normal	0.631185247	0.105136572	normal	[OJ]	"Posttranslational modification, protein turnover, chaperones;; Translation, ribosomal structure and biogenesis"	--	"K18763|0|hsa:23185|LARP4B, KIAA0217, LARP5; La ribonucleoprotein domain family, member 4B; K18763 la-related protein 4 (A)"	--	[T]	Signal transduction mechanisms	La domain	La-related protein 4B GN=LARP4B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: la-related protein 4B isoform X3 [Oryctolagus cuniculus]
ENSG00000107937(GTPBP4)	--	25.28400339	2572	21.54729292	2211	22.77844609	2315	23.58873978	2360	26.51846054	2685	19.96043954	2033	0.981809149	-0.154839441	normal	0.958132129	0.258635764	normal	0.9738172	-0.195556995	normal	0.937103078	-0.025601699	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K06943|0|hsa:23560|GTPBP4, CRFG, NGB, NOG1; GTP binding protein 4; K06943 nucleolar GTP-binding protein (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	Nucleolar GTP-binding protein 1 (NOG1);; NOGCT (NUC087) domain;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B;; Miro-like protein	Nucleolar GTP-binding protein 1 GN=GTPBP4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: nucleolar GTP-binding protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000107938(EDRF1)	--	6.835551059	425	6.372122198	446	7.43451128	500	7.216513004	503	9.160502685	643	6.880090503	503	0.943299147	0.211559663	normal	0.383508197	0.504915348	normal	0.971871647	0.000337844	normal	0.279379339	0.245547975	normal	--	--	--	--	--	--	--	--	Erythroid differentiation-related factor 1 GN=EDRF1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: erythroid differentiation-related factor 1 isoform X2 [Tupaia chinensis]
ENSG00000107949(BCCIP)	--	54.28517	1346	51.71825	1338	51.26456	1286	55.87982	1413	52.14077	1294	37.73117	940	0.982658873	0.039207112	normal	0.980608273	-0.069587073	normal	0.503140284	-0.459814286	normal	0.603354954	-0.144829049	normal	--	--	--	"K15262|3.04617e-160|hsa:56647|BCCIP, TOK-1, TOK1; BRCA2 and CDKN1A interacting protein; K15262 protein BCP1 (A)"	--	[R]	General function prediction only	p21-C-terminal region-binding protein	BRCA2 and CDKN1A-interacting protein GN=BCCIP OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: BRCA2 and CDKN1A-interacting protein-like [Ceratotherium simum simum]
ENSG00000107951(MTPAP)	--	9.99024979	673	11.44078873	661	9.759978657	604	9.450518	587	11.924818	597	8.755709	571	0.940392509	-0.227521531	normal	0.958664518	-0.16794138	normal	0.969912845	-0.089119716	normal	0.492580249	-0.164520987	normal	[L]	"Replication, recombination and repair"	--	"K18060|0|hsa:55149|MTPAP, PAPD1, SPAX4; mitochondrial poly(A) polymerase (EC:2.7.7.19); K18060 poly(A) RNA polymerase, mitochondrial [EC:2.7.7.19] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cid1 family poly A polymerase	"Poly(A) RNA polymerase, mitochondrial (Precursor) GN=MTPAP OS=Homo sapiens (Human) PE=1 SV=1"	D	"Cell cycle control, cell division, chromosome partitioning"	"PREDICTED: poly(A) RNA polymerase, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000107954(NEURL1)	--	0.582361442	13	0.234287047	10	0.044214181	2	0.106030716	6	0.264896873	12	0.06115694	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K01931|0|nle:100602121|NEURL; neuralized homolog (Drosophila); K01931 protein neuralized [EC:6.3.2.19] (A)	--	[T]	Signal transduction mechanisms	"Neuralized;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase NEURL1 GN=NEURL1 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: neuralized-like protein 1A [Pteropus alecto]
ENSG00000107957(SH3PXD2A)	--	1.082283894	274	1.448862821	370	0.923903542	235	1.738939092	438	2.366827783	594	2.043319983	517	0.080720059	0.643047158	normal	0.042927709	0.659365602	normal	6.43E-07	1.124210194	up	0.002795749	0.796197156	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	--	--	--	--	SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; PX domain;; Bacterial SH3 domain	SH3 and PX domain-containing protein 2A GN=SH3PXD2A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH3 and PX domain-containing protein 2A isoform X1 [Myotis brandtii]
ENSG00000107959(PITRM1)	--	26.81286315	1791	27.82756378	1880	30.81471197	2025	38.06213265	2571	32.78816391	2187	32.937374	2223	0.400253449	0.490379213	normal	0.972309522	0.196647228	normal	0.982802819	0.126204614	normal	0.103460994	0.271966831	normal	[R]	General function prediction only	Biological Process: proteolysis (GO:0006508);; 	"K06972|0|hsa:10531|PITRM1, MP1, PreP; pitrilysin metallopeptidase 1; K06972 (A)"	--	[RO]	"General function prediction only;; Posttranslational modification, protein turnover, chaperones"	Peptidase M16C associated;; Peptidase M16 inactive domain;; Insulinase (Peptidase family M16)	"Presequence protease, mitochondrial (Precursor) GN=PITRM1 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: presequence protease, mitochondrial [Oryctolagus cuniculus]"
ENSG00000107960(STN1)	--	9.2320444	366	7.157467875	304	8.923400797	315	9.430091856	353	10.355367	370	8.283658009	291	0.965758562	-0.082654383	normal	0.920906275	0.260849601	normal	0.960997561	-0.12201448	normal	0.967635723	0.020118192	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[L]	"Replication, recombination and repair"	"CST, Suppressor of cdc thirteen homolog, complex subunit STN1;; OB-fold nucleic acid binding domain;; Telomere regulation protein Stn1"	CST complex subunit STN1 GN=OBFC1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: CST complex subunit STN1 isoform 2 [Trichechus manatus latirostris]
ENSG00000107968(MAP3K8)	--	18.63318716	950	18.44491706	988	15.58875103	831	12.18284311	599	13.06297594	669	23.22423006	1313	0.009353022	-0.694775013	normal	0.10938809	-0.582839872	normal	0.020825638	0.650705014	normal	0.884468846	-0.120527823	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04415|0|hsa:1326|MAP3K8, COT, EST, ESTF, MEKK8, TPL2, Tpl-2, c-COT; mitogen-activated protein kinase kinase kinase 8 (EC:2.7.11.25); K04415 mitogen-activated protein kinase kinase kinase 8 [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010);; Toll-like receptor signaling pathway (ko04620);; T cell receptor signaling pathway (ko04660);; TNF signaling pathway (ko04668)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase 8 GN=MAP3K8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 8 [Odobenus rosmarus divergens]
ENSG00000107984(DKK1)	--	189.556066	4693	152.0434046	3764	187.9531722	4623	104.1951937	2611	115.5730568	2862	91.71746485	2282	1.92E-05	-0.876349689	normal	0.772119642	-0.416476956	normal	7.03E-08	-1.026334011	down	1.07E-06	-0.775450681	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: negative regulation of Wnt signaling pathway (GO:0030178);; 	"K02165|5.17147e-176|hsa:22943|DKK1, DKK-1, SK; dickkopf WNT signaling pathway inhibitor 1; K02165 dickkopf (A)"	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Dickkopf N-terminal cysteine-rich region	Dickkopf-related protein 1 (Precursor) GN=DKK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dickkopf-related protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000108001(EBF3)	--	0.013474422	1	0	0	0	0	0.053535312	4	0.052367309	2	0.026583729	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09103|0|rno:361668|Ebf3; early B-cell factor 3; K09103 early B-cell factor (A)	--	[K]	Transcription	IPT/TIG domain	Transcription factor COE3 GN=EBF3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor COE3 isoform X2 [Eptesicus fuscus]
ENSG00000108010(GLRX3)	--	71.81621	1667	79.46167	1831	76.82267	1748	84.75814	2039	75.09623	1713	77.59946	1828	0.949598835	0.259558813	normal	0.981048746	-0.117432895	normal	0.984939046	0.056221876	normal	0.782426933	0.067436358	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Cellular Component: spliceosomal complex (GO:0005681);; Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Biological Process: cell redox homeostasis (GO:0045454);; "	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutaredoxin;; Thioredoxin;; SH3-binding, glutamic acid-rich protein;; Mitosis protein DIM1;; Thioredoxin-like domain;; Phosducin"	Glutaredoxin-3 GN=GLRX3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	glutaredoxin-3 [Panthera tigris altaica]
ENSG00000108021(FAM208B)	--	19.054313	3100	21.881365	3224	19.57384675	3285	20.990637	3339	18.92439	3222	21.531221	3589	0.989579059	0.076279184	normal	0.990375761	-0.022311339	normal	0.988209428	0.119344532	normal	0.821394419	0.05808772	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3715);; Protein of unknown function (DUF3699)	Protein FAM208B GN=FAM208B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM208B [Galeopterus variegatus]
ENSG00000108039(XPNPEP1)	--	18.99053695	908	16.8943082	809	19.28649222	918	23.67984791	1133	21.71596639	1028	18.3882314	872	0.913187661	0.288114245	normal	0.876030776	0.323664254	normal	0.9755872	-0.082318303	normal	0.371713844	0.181126392	normal	[E]	Amino acid transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K01262|0|pps:100973814|XPNPEP1; X-prolyl aminopeptidase (aminopeptidase P) 1, soluble; K01262 Xaa-Pro aminopeptidase [EC:3.4.11.9] (A)"	--	[E]	Amino acid transport and metabolism	Metallopeptidase family M24;; Creatinase/Prolidase N-terminal domain	Xaa-Pro aminopeptidase 1 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: xaa-Pro aminopeptidase 1 isoformX4 [Canis lupus familiaris]
ENSG00000108055(SMC3)	--	26.8958	2565	29.1614	2777	30.6536	2871	25.3436	2429	24.6515	2347	24.1624	2300	0.985798217	-0.109361269	normal	0.957136874	-0.263979307	normal	0.911568641	-0.328017455	normal	0.173404601	-0.236216143	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: chromosome (GO:0005694);; Biological Process: chromosome organization (GO:0051276);; 	K06669|0|umr:103657014|SMC3; structural maintenance of chromosomes 3; K06669 structural maintenance of chromosome 3 (chondroitin sulfate proteoglycan 6) (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114)	[D]	"Cell cycle control, cell division, chromosome partitioning"	RecF/RecN/SMC N terminal domain;; SMC proteins Flexible Hinge Domain;; AAA domain;; AAA domain	Structural maintenance of chromosomes protein 3 GN=SMC3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: structural maintenance of chromosomes protein 3 [Elephantulus edwardii]
ENSG00000108061(SHOC2)	--	14.64708922	893	15.91649488	959	15.14846666	898	17.87890555	1101	14.21654117	892	14.78296575	939	0.925649877	0.270829866	normal	0.971349373	-0.125708059	normal	0.977411723	0.056025997	normal	0.78643806	0.07062737	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeat	Leucine-rich repeat protein SHOC-2 GN=SHOC2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat protein SHOC-2 isoform X1 [Camelus ferus] 
ENSG00000108064(TFAM)	--	37.39463933	1727	30.70864709	1686	35.64036161	1613	33.754267	1855	34.91875729	1684	30.28380706	1536	0.984315033	0.07225681	normal	0.984712501	-0.023118207	normal	0.982633616	-0.078783962	normal	0.985247992	-0.007861841	normal	--	--	--	"K11830|0|ggo:101124511|TFAM; transcription factor A, mitochondrial isoform 1; K11830 transcription factor A, mitochondrial (A)"	Huntington's disease (ko05016)	[R]	General function prediction only	HMG (high mobility group) box;; HMG-box domain	"Transcription factor A, mitochondrial (Precursor) GN=TFAM OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: transcription factor A, mitochondrial [Tupaia chinensis]"
ENSG00000108091(CCDC6)	--	18.4799	1765	18.4685	1751	19.3623	1819	22.7915	2181	23.1352	2206	19.4836	1866	0.943616373	0.274274223	normal	0.918233927	0.311586934	normal	0.985901871	0.028488616	normal	0.247873695	0.207520461	normal	--	--	--	K09288|0|ptr:466080|CCDC6; coiled-coil domain containing 6; K09288 coiled-coil domain-containing protein 6 (A)	Pathways in cancer (ko05200);; Thyroid cancer (ko05216)	[S]	Function unknown	Uncharacterized conserved protein H4 (DUF2046)	Coiled-coil domain-containing protein 6 GN=CCDC6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 6 [Orycteropus afer afer]
ENSG00000108094(CUL2)	--	22.2945976	1374	22.83412079	1313	24.60160698	1415	17.35180835	1049	16.99857707	992	16.32270792	968	0.661822641	-0.419660639	normal	0.656380013	-0.425315837	normal	0.143974125	-0.555292577	normal	0.002120078	-0.468379973	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	"K03870|0|mcf:102118914|CUL2, Cullin-2; cullin 2; K03870 cullin 2 (A)"	HIF-1 signaling pathway (ko04066);; Ubiquitin mediated proteolysis (ko04120);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cullin family;; Cullin protein neddylation domain	Cullin-2 GN=CUL2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"Cullin-2, partial [Bos mutus]"
ENSG00000108100(CCNY)	--	21.15343014	1426	19.67527343	1367	20.39468624	1386	24.35967267	1648	20.95992728	1418	22.71945923	1559	0.971379856	0.177731758	normal	0.982545816	0.031383643	normal	0.973660139	0.161236263	normal	0.55632925	0.124870139	normal	--	--	Biological Process: regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079);; Molecular Function: protein kinase binding (GO:0019901);; 	--	--	[R]	General function prediction only	"Cyclin, N-terminal domain;; Cyclin"	Cyclin-Y GN=CCNY OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cyclin-Y [Pteropus alecto] 
ENSG00000108106(UBE2S)	--	154.349387	6322	148.1078587	5661	178.880369	6430	147.6847556	5035	112.7721611	4387	108.377586	4142	0.918238364	-0.359123472	normal	0.872997181	-0.389130334	normal	0.028850701	-0.642592762	normal	0.002643762	-0.46260192	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K10583|4.97142e-133|hsa:27338|UBE2S, E2-EPF, E2EPF, EPF5; ubiquitin-conjugating enzyme E2S (EC:6.3.2.19); K10583 ubiquitin-conjugating enzyme E2 S [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 S GN=UBE2S OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 S [Lipotes vexillifer]
ENSG00000108107(RPL28)	--	1074.429915	11785	905.747829	10590	998.2801843	11225	1095.864643	13276	1177.527856	14299	1104.03645	12833	0.995286425	0.141019184	normal	0.903003874	0.411734338	normal	0.993341057	0.18482828	normal	0.214113751	0.24496902	normal	--	--	--	K02903|4.14636e-74|pon:100453548|RPL28; ribosomal protein L28; K02903 large subunit ribosomal protein L28e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L28e protein family	60S ribosomal protein L28 GN=RPL28 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L28 isoform 2 [Canis lupus familiaris]
ENSG00000108175(ZMIZ1)	--	27.8850916	3850	23.545605	3302	22.72360125	3477	29.78254	4201	33.01251	4664	28.374484	4311	0.990616923	0.095005775	normal	0.565988393	0.47661661	normal	0.949622319	0.301769964	normal	0.084787002	0.288827234	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[K]	Transcription	MIZ/SP-RING zinc finger;; Zinc-finger of the MIZ type in Nse subunit	Zinc finger MIZ domain-containing protein 1 GN=ZMIZ1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger MIZ domain-containing protein 1 isoform X1 [Sus scrofa]
ENSG00000108176(DNAJC12)	--	12.57881	271	12.66156642	276	16.08310459	345	21.44257194	475	23.98144141	517	28.666943	626	0.005730438	0.775441658	normal	0.000522116	0.880489589	normal	0.000508562	0.848473837	normal	6.47E-05	0.839162629	normal	--	--	--	"K09532|1.83985e-156|ptr:466287|DNAJC12; DnaJ (Hsp40) homolog, subfamily C, member 12; K09532 DnaJ homolog subfamily C member 12 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 12 GN=DNAJC12 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 12 [Sus scrofa]
ENSG00000108179(PPIF)	--	44.006202	1608	38.09803416	1412	41.88728027	1543	72.7352815	2686	72.588449	2626	62.343331	2289	0.003881307	0.708830327	normal	3.99E-05	0.873004155	normal	0.132799914	0.560234308	normal	2.27E-07	0.714636253	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K09565|6.80999e-138|hsa:10105|PPIF, CYP3, CyP-M, Cyp-D, CypD; peptidylprolyl isomerase F (EC:5.2.1.8); K09565 peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Parkinson's disease (ko05012);; Huntington's disease (ko05016);; Toxoplasmosis (ko05145)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial (Precursor) GN=PPIF OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: peptidyl-prolyl cis-trans isomerase F, mitochondrial [Orycteropus afer afer]"
ENSG00000108187(PBLD)	--	1.5612	48	1.637462518	64	0.816748	29	2.338939408	90	3.391107186	133	2.940569875	117	0.344135518	0.855760156	normal	0.016785359	1.016841712	normal	6.78E-08	1.949541309	up	0.000666009	1.248413136	up	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; Biological Process: biosynthetic process (GO:0009058);; 	--	--	[R]	General function prediction only	Phenazine biosynthesis-like protein	Phenazine biosynthesis-like domain-containing protein GN=PBLD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: phenazine biosynthesis-like domain-containing protein [Orycteropus afer afer]
ENSG00000108219(TSPAN14)	--	121.5207331	6111	100.7923317	4742	113.0888397	5386	130.1768808	6311	143.9637402	7108	105.4518025	5391	0.994459537	0.015624013	normal	0.217974737	0.562374046	normal	0.993784051	-0.006950812	normal	0.445305484	0.190543576	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17296|5.07118e-175|pps:100982373|TSPAN14; tetraspanin 14; K17296 tetraspanin-14 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-14 GN=TSPAN14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	tetraspanin-14 [Bos taurus] 
ENSG00000108239(TBC1D12)	--	4.191563	325	3.568359	282	4.698075	360	3.88267	307	3.326526	258	4.450660015	350	0.96218829	-0.112486058	normal	0.955820572	-0.148915396	normal	0.967841966	-0.048725827	normal	0.777342402	-0.100271282	normal	[R]	General function prediction only	--	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 12 GN=TBC1D12 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: TBC1 domain family member 12 [Trichechus manatus latirostris]
ENSG00000108242(CYP2C18)	--	0.048499424	2	0	0	0	0	0.0224839	1	0.068948485	1	0.085127408	3	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17720|0|hsa:1562|CYP2C18, CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17; cytochrome P450, family 2, subfamily C, polypeptide 18 (EC:1.14.14.1); K17720 cytochrome P450, family 2, subfamily C, polypeptide 18 [EC:1.14.14.1] (A)"	Retinol metabolism (ko00830);; Serotonergic synapse (ko04726);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2C18 GN=CYP2C18 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2C26-like isoform 2 [Ceratotherium simum simum]
ENSG00000108244(KRT23)	--	0.040818527	2	0	0	0.030020004	0	0.10644837	2	0.105085101	1	0.030143469	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|pps:100990255|KRT23; keratin 23 (histone deacetylase inducible); K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 23 GN=KRT23 OS=Homo sapiens (Human) PE=1 SV=2"	B	Chromatin structure and dynamics	"PREDICTED: keratin, type I cytoskeletal 23 [Galeopterus variegatus]"
ENSG00000108255(CRYBA1)	--	0	0	0.093133	1	0.184131	1	0.0929213	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Beta/Gamma crystallin;; Peptidase inhibitor family I36	"Beta-crystallin A3, isoform A1, Delta8 form GN=CRYBA1 OS=Homo sapiens (Human) PE=1 SV=4"	R	General function prediction only	beta-crystallin A3 [Oryctolagus cuniculus] 
ENSG00000108256(NUFIP2)	--	28.0152836	4173	29.7326489	4573	29.71650246	4160	27.5865546	4452	29.948154	4711	30.9324172	4677	0.991997734	0.062514124	normal	0.992726314	0.021458863	normal	0.98763474	0.16065335	normal	0.74029152	0.079674144	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	--	--	--	--	Nuclear fragile X mental retardation-interacting protein 2	Nuclear fragile X mental retardation-interacting protein 2 GN=NUFIP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nuclear fragile X mental retardation-interacting protein 2 [Galeopterus variegatus]
ENSG00000108262(GIT1)	--	37.209106	2842	35.19039703	2788	38.6217146	3030	39.1801305	2963	31.307133	2395	27.14020401	2117	0.989814626	0.029304293	normal	0.965962763	-0.240490559	normal	0.25945327	-0.525272588	normal	0.222832775	-0.234407597	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	K05737|0|hsa:28964|GIT1; G protein-coupled receptor kinase interacting ArfGAP 1; K05737 G protein-coupled receptor kinase interactor 1 (A)	Endocytosis (ko04144);; Regulation of actin cytoskeleton (ko04810);; Epithelial cell signaling in Helicobacter pylori infection (ko05120)	[T]	Signal transduction mechanisms	G protein-coupled receptor kinase-interacting protein 1 C term;; Spa2 homology domain (SHD) of GIT;; Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	ARF GTPase-activating protein GIT1 GN=GIT1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ARF GTPase-activating protein GIT1 [Camelus dromedarius]
ENSG00000108298(RPL19)	--	1679.7525	18068	1542.975856	17040	1518.24256	16898	1598.41249	17951	1650.791058	17754	1561.534926	17181	0.997650056	-0.040201438	normal	0.997461419	0.037788923	normal	0.9975779	0.015668673	normal	0.996314771	0.00283978	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02885|3.71075e-87|phi:102107451|RPL19; ribosomal protein L19; K02885 large subunit ribosomal protein L19e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L19e	60S ribosomal protein L19 GN=RPL19 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L19 isoform X1 [Ornithorhynchus anatinus] 
ENSG00000108306(FBXL20)	--	7.291503583	677	7.02083869	648	7.741645232	689	8.392609001	765	6.773915523	642	8.885986633	820	0.965375089	0.145161615	normal	0.973365461	-0.03476556	normal	0.93667249	0.242340336	normal	0.615529887	0.124058495	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10268|0|ptg:102959217|FBXL20; F-box and leucine-rich repeat protein 20; K10268 F-box and leucine-rich repeat protein 2/20 (A)	--	[R]	General function prediction only	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; F-box-like;; Leucine rich repeat;; Leucine Rich Repeat;; F-box domain;; Leucine rich repeat	F-box/LRR-repeat protein 20 GN=FBXL20 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	F-box/LRR-repeat protein 20 [Bos taurus] 
ENSG00000108309(RUNDC3A)	--	0.177345261	8	0.3205986	14	0.177705858	7	0.066191452	3	0.205684138	8	0.055204607	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	RUN domain	RUN domain-containing protein 3A GN=RUNDC3A OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: RUN domain-containing protein 3A isoform X5 [Felis catus]
ENSG00000108312(UBTF)	--	27.39429018	2648	28.53831114	2800	26.17679221	2548	23.3386139	2414	25.257366	2551	20.36247124	2072	0.981043368	-0.164209869	normal	0.98249124	-0.155702342	normal	0.926974263	-0.306430654	normal	0.254002617	-0.206012862	normal	--	--	--	K09273|0|mcf:101865480|uncharacterized LOC101865480; K09273 upstream-binding transcription factor (A)	--	[R]	General function prediction only	HMG (high mobility group) box;; HMG (high mobility group) box 5;; HMG-box domain	Nucleolar transcription factor 1 GN=UBTF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nucleolar transcription factor 1 isoform X1 [Pteropus alecto] 
ENSG00000108342(CSF3)	--	0.040525346	1	0.083512503	2	0	0	0.346364285	9	0.08235681	1	0.799832968	21	--	--	--	--	--	--	0.00217057	3.892046042	up	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; 	"K05423|4.18979e-144|hsa:1440|CSF3, C17orf33, CSF3OS, GCSF, G-CSF; colony stimulating factor 3 (granulocyte); K05423 granulocyte colony-stimulating factor (A)"	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Malaria (ko05144)	--	--	Interleukin-6/G-CSF/MGF family	Granulocyte colony-stimulating factor (Precursor) GN=CSF3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: granulocyte colony-stimulating factor isoform X2 [Galeopterus variegatus]
ENSG00000108344(PSMD3)	--	87.41439	3603	91.84397	3767	85.14417	3613	97.06183	3999	103.47074	4242	87.65291	3634	0.989074642	0.119559959	normal	0.98736482	0.149845317	normal	0.991529262	6.97E-05	normal	0.691636075	0.091197898	normal	--	--	Cellular Component: proteasome complex (GO:0000502);; Molecular Function: protein binding (GO:0005515);; Molecular Function: enzyme regulator activity (GO:0030234);; Biological Process: regulation of protein catabolic process (GO:0042176);; 	"K03033|0|hsa:5709|PSMD3, P58, RPN3, S3, TSTA2; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3; K03033 26S proteasome regulatory subunit N3 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome regulatory subunit C-terminal;; PCI domain	26S proteasome non-ATPase regulatory subunit 3 GN=PSMD3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 3 [Balaenoptera acutorostrata scammoni]
ENSG00000108349(CASC3)	--	22.52231	1903	21.29806	1803	22.91963	1938	21.72009	1827	22.69157	1905	21.840548	1834	0.983897585	-0.089557386	normal	0.984879029	0.05791778	normal	0.98413256	-0.087795937	normal	0.879704748	-0.04113812	normal	--	--	--	"K14323|0|hsa:22794|CASC3, BTZ, MLN51; cancer susceptibility candidate 3; K14323 protein CASC3 (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[R]	General function prediction only	CASC3/Barentsz eIF4AIII binding	Protein CASC3 GN=CASC3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: protein CASC3 [Odobenus rosmarus divergens]
ENSG00000108352(RAPGEFL1)	--	2.093672478	117	1.858087831	85	1.580989571	71	1.320172756	64	1.753369988	78	1.442457883	80	0.116072868	-0.885232096	normal	0.967624604	-0.142762757	normal	0.969180168	0.160663999	normal	0.53511126	-0.319341088	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[T]	Signal transduction mechanisms	RasGEF domain	Rap guanine nucleotide exchange factor-like 1 GN=RAPGEFL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rap guanine nucleotide exchange factor-like 1 isoform X2 [Mustela putorius furo]
ENSG00000108370(RGS9)	--	7.258777146	273	7.218442503	257	6.0623599	225	8.260494703	259	5.812333917	251	6.990526533	228	0.962367005	-0.106167552	normal	0.964881966	-0.055178989	normal	0.966981941	0.010745633	normal	0.902805225	-0.054681389	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Cellular Component: heterotrimeric G-protein complex (GO:0005834);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Biological Process: intracellular signal transduction (GO:0035556);; 	K13765|0|pps:100989672|RGS9; regulator of G-protein signaling 9; K13765 regulator of G-protein signaling 9 (A)	Phototransduction (ko04744);; Cocaine addiction (ko05030)	[T]	Signal transduction mechanisms	"Regulator of G protein signaling domain;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; GGL domain"	Regulator of G-protein signaling 9 GN=RGS9 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 9 isoform X1 [Tupaia chinensis]
ENSG00000108375(RNF43)	--	71.61251121	1448	64.07404739	1356	77.80997618	1408	81.14887638	1624	87.70620248	1925	87.13270814	1690	0.977815344	0.134522939	normal	0.437666406	0.483619917	normal	0.947175366	0.254834315	normal	0.075675262	0.293814703	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K15694|0|hsa:54894|RNF43, RNF124, URCC; ring finger protein 43; K15694 RING finger protein 43 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF43 (Precursor) GN=RNF43 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF43 isoform X1 [Galeopterus variegatus]
ENSG00000108379(WNT3)	--	5.925170391	451	5.521064	447	6.083002	470	5.723889	413	7.419107308	554	6.25283421	480	0.957275303	-0.157257815	normal	0.902936638	0.287310041	normal	0.971123938	0.022012121	normal	0.86000755	0.060431645	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00312|0|ptr:468297|WNT3; wingless-type MMTV integration site family, member 3; K00312 wingless-type MMTV integration site family, member 3 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Proto-oncogene Wnt-3 (Precursor) GN=WNT3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: proto-oncogene Wnt-3 [Erinaceus europaeus]
ENSG00000108384(RAD51C)	--	41.75890261	629	36.76495634	685	45.63278456	732	41.90630448	729	38.50053904	644	38.24967453	693	0.956876936	0.1816142	normal	0.968639654	-0.110218844	normal	0.972378191	-0.087094782	normal	0.986272296	-0.007179041	normal	[L]	"Replication, recombination and repair"	--	K10870|0|pon:100459841|RAD51C; RAD51 paralog C; K10870 RAD51-like protein 2 (A)	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Rad51;; AAA domain;; KaiC	DNA repair protein RAD51 homolog 3 GN=RAD51C OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein RAD51 homolog 3 isoform X1 [Galeopterus variegatus]
ENSG00000108387(SEPT4)	--	2.058046129	59	0.5430329	19	1.43046171	40	1.415703205	40	3.649529752	99	2.074485565	60	0.907865173	-0.573296653	normal	1.35E-08	2.272336108	up	0.911855488	0.559297695	normal	0.434044983	0.734344304	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	"K16943|0|hsa:5414|SEPT4, ARTS, BRADEION, CE5B3, H5, MART, PNUTL2, SEP4, hCDCREL-2; septin 4; K16943 septin 4 (A)"	--	[DZU]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	"Septin;; 50S ribosome-binding GTPase;; Protein of unknown function, DUF258;; Elongation factor Tu GTP binding domain"	Septin-4 GN=SEPT4 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: septin-4 [Camelus ferus]
ENSG00000108389(MTMR4)	--	12.3782281	1395	9.583902223	1087	11.660404	1314	10.53123875	1182	7.990556341	890	8.478305892	948	0.933570352	-0.269544376	normal	0.894299882	-0.309424606	normal	0.422346545	-0.478646222	normal	0.106065122	-0.351758666	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K18082|0|hsa:9110|MTMR4, FYVE-DSP2, ZFYVE11; myotubularin related protein 4 (EC:3.1.3.48); K18082 myotubularin-related protein 3/4 [EC:3.1.3.48] (A)"	--	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	Myotubularin-like phosphatase domain;; FYVE zinc finger	Myotubularin-related protein 4 GN=MTMR4 OS=Homo sapiens (Human) PE=1 SV=2	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: myotubularin-related protein 4 isoform X1 [Equus caballus] 
ENSG00000108395(TRIM37)	--	18.29604801	1482	19.67931026	1600	18.93083984	1500	16.25545832	1316	15.00166781	1215	20.93097761	1675	0.964190475	-0.201995816	normal	0.69117753	-0.418087098	normal	0.976327454	0.150763249	normal	0.561693745	-0.144094762	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	K10608|0|ptr:455163|TRIM37; tripartite motif containing 37; K10608 tripartite motif-containing protein 37 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	B-box zinc finger;; MATH domain	E3 ubiquitin-protein ligase TRIM37 GN=TRIM37 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM37 isoform X3 [Ailuropoda melanoleuca]
ENSG00000108405(P2RX1)	--	0	0	0.0194175	1	0	0	0	0	0.0188952	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: purinergic nucleotide receptor activity (GO:0001614);; Molecular Function: extracellular ATP-gated cation channel activity (GO:0004931);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: response to ATP (GO:0033198);; Biological Process: cation transmembrane transport (GO:0098655);; 	"K05215|0|hsa:5023|P2RX1, P2X1; purinergic receptor P2X, ligand-gated ion channel, 1; K05215 P2X purinoceptor 1 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Platelet activation (ko04611)	--	--	ATP P2X receptor	P2X purinoceptor 1 GN=P2RX1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: P2X purinoceptor 1 [Galeopterus variegatus]
ENSG00000108406(DHX40)	--	41.79417133	2636	34.41004877	2205	36.39764237	2238	30.73211978	1967	35.90049118	2221	29.38550432	1877	0.5776904	-0.452878851	normal	0.987427076	-0.010988312	normal	0.95152611	-0.261879334	normal	0.156014068	-0.244384988	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	K18711|0|pon:100173154|DHX40; DEAH (Asp-Glu-Ala-His) box polypeptide 40 (EC:3.6.4.13); K18711 ATP-dependent RNA helicase DHX40 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; Type II/IV secretion system protein	Probable ATP-dependent RNA helicase DHX40 GN=DHX40 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DHX40 isoformX1 [Sus scrofa]
ENSG00000108417(KRT37)	--	0	0	0	0	0	0	0.0317329	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:8688|KRT37, HA7, K37, KRTHA7; keratin 37; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cuticular Ha7 GN=KRT37 OS=Homo sapiens (Human) PE=2 SV=3"	S	Function unknown	"PREDICTED: keratin, type I cuticular Ha7 [Tupaia chinensis]"
ENSG00000108423(TUBD1)	--	8.649090002	256	6.888829457	254	7.403396045	262	7.304200601	254	9.161252473	329	5.613056414	210	0.966481811	-0.041895145	normal	0.853602126	0.349997102	normal	0.888740684	-0.325366766	normal	0.976817231	0.01725975	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K10390|0|pps:100979143|TUBD1; tubulin, delta 1; K10390 tubulin delta (A)"	--	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain"	Tubulin delta chain GN=TUBD1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tubulin delta chain isoform 1 [Ceratotherium simum simum]
ENSG00000108424(KPNB1)	--	151.3518499	14146	155.6839123	15227	160.8516182	15369	159.0526633	15298	160.3325596	14649	130.5396016	12156	0.996888437	0.082108047	normal	0.996836659	-0.077248284	normal	0.963876063	-0.346607719	normal	0.666880731	-0.109476117	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	K14293|0|pps:100982939|KPNB1; karyopherin (importin) beta 1; K14293 importin subunit beta-1 (A)	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	HEAT-like repeat;; HEAT repeat;; HEAT repeats;; Importin-beta N-terminal domain;; Armadillo/beta-catenin-like repeat	Importin subunit beta-1 GN=KPNB1 OS=Homo sapiens (Human) PE=1 SV=2	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: importin subunit beta-1 [Ochotona princeps]
ENSG00000108433(GOSR2)	--	21.88218551	1416	22.54635955	1508	23.10792151	1392	23.78637697	1425	27.2453347	1548	23.09556492	1415	0.98332486	-0.021668173	normal	0.9837731	0.016326326	normal	0.983307713	0.015334876	normal	0.997159335	0.002606262	normal	--	--	--	K08496|1.61299e-121|ptr:454817|GOSR2; golgi SNAP receptor complex member 2; K08496 golgi SNAP receptor complex member 2 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snare region anchored in the vesicle membrane C-terminus	Golgi SNAP receptor complex member 2 GN=GOSR2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi SNAP receptor complex member 2 [Ochotona princeps]
ENSG00000108439(PNPO)	--	18.00724034	887	15.1410245	758	19.0415947	938	26.18317201	1355	26.66120204	1374	18.416975	934	0.092867231	0.579636785	normal	0.000214042	0.835430367	normal	0.978776126	-0.014433495	normal	0.082324288	0.482104715	normal	[H]	Coenzyme transport and metabolism	Molecular Function: FMN binding (GO:0010181);; 	K00275|0|pps:100987061|PNPO; pyridoxamine 5'-phosphate oxidase; K00275 pyridoxamine 5'-phosphate oxidase [EC:1.4.3.5] (A)	Vitamin B6 metabolism (ko00750)	[H]	Coenzyme transport and metabolism	Pyridoxamine 5'-phosphate oxidase;; Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region;; Pyridoxamine 5'-phosphate oxidase	Pyridoxine-5'-phosphate oxidase GN=PNPO OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: pyridoxine-5'-phosphate oxidase [Ursus maritimus]
ENSG00000108443(RPS6KB1)	--	21.31763416	1649	23.48486769	1792	21.30743401	1657	20.34071656	1629	23.84157295	1820	18.27273137	1412	0.984264341	-0.048391693	normal	0.98555441	0.000940468	normal	0.954083767	-0.238888503	normal	0.695273137	-0.090264588	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04688|0|ptr:468426|RPS6KB1; ribosomal protein S6 kinase, 70kDa, polypeptide 1; K04688 p70 ribosomal S6 kinase [EC:2.7.11.1] (A)"	ErbB signaling pathway (ko04012);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; TGF-beta signaling pathway (ko04350);; Fc gamma R-mediated phagocytosis (ko04666);; Insulin signaling pathway (ko04910);; Proteoglycans in cancer (ko05205);; Acute myeloid leukemia (ko05221);; Choline metabolism in cancer (ko05231)	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Protein kinase C terminal domain;; Kinase-like	Ribosomal protein S6 kinase beta-1 GN=RPS6KB1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ribosomal protein S6 kinase beta-1 isoform X1 [Galeopterus variegatus]
ENSG00000108448(TRIM16L)	--	81.59972	2916	78.02453069	2902	77.2997722	2804	94.44014858	3412	130.3744719	4574	116.0745265	4276	0.979648959	0.195699268	normal	0.037737372	0.634716704	normal	0.067833864	0.600220026	normal	0.007985134	0.487585509	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12006|0|hsa:147166|TRIM16L, TRIM70; tripartite motif containing 16-like; K12006 tripartite motif-containing protein 16 (A)"	--	--	--	SPRY domain;; SPRY-associated domain	Tripartite motif-containing protein 16-like protein GN=TRIM16L OS=Homo sapiens (Human) PE=2 SV=3	B	Chromatin structure and dynamics	PREDICTED: tripartite motif-containing protein 16-like [Myotis brandtii]
ENSG00000108465(CDK5RAP3)	--	49.55551213	1925	43.6232532	1839	44.5432158	1772	43.38785555	1789	47.87810314	1983	55.52828747	2235	0.980168246	-0.136424333	normal	0.983941465	0.087267522	normal	0.901160037	0.326356255	normal	0.666965354	0.097192482	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Protein of unknown function (DUF773)	CDK5 regulatory subunit-associated protein 3 GN=CDK5RAP3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: CDK5 regulatory subunit-associated protein 3 [Trichechus manatus latirostris]
ENSG00000108468(CBX1)	--	66.93535682	3013	66.10434386	3029	70.36640188	3180	79.84872165	3606	68.35814254	3013	66.52211243	2969	0.974003123	0.228259955	normal	0.989830352	-0.029052919	normal	0.98788824	-0.107288298	normal	0.899494571	0.034405255	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	K11585|4.43098e-83|bacu:103011170|CBX1; chromobox homolog 1; K11585 chromobox protein 1 (A)	--	[B]	Chromatin structure and dynamics	Chromo shadow domain;; Chromo (CHRromatin Organisation MOdifier) domain	Chromobox protein homolog 1 GN=CBX1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: chromobox protein homolog 1 [Sorex araneus]
ENSG00000108469(RECQL5)	--	13.94102634	750	10.8360046	711	11.49268896	706	10.42184062	650	10.13579024	614	13.06234	759	0.937828454	-0.23676157	normal	0.938974722	-0.232504734	normal	0.971957319	0.095942017	normal	0.628904125	-0.120009728	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K10902|0|ggo:101137561|RECQL5; ATP-dependent DNA helicase Q5 isoform 1; K10902 ATP-dependent DNA helicase Q5 [EC:3.6.4.12] (A)	--	[L]	"Replication, recombination and repair"	"RecQ helicase protein-like 5 (RecQ5);; DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	ATP-dependent DNA helicase Q5 GN=RECQL5 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: ATP-dependent DNA helicase Q5 [Ceratotherium simum simum]
ENSG00000108474(PIGL)	--	15.10046	192	14.151335	172	13.458622	163	14.789516	204	17.19474	223	13.65892	185	0.965850178	0.056194307	normal	0.877892752	0.350495546	normal	0.95546347	0.172855616	normal	0.612274373	0.194159397	normal	[S]	Function unknown	--	"K03434|2.82953e-165|hsa:9487|PIGL, CHIME; phosphatidylinositol glycan anchor biosynthesis, class L (EC:3.5.1.89); K03434 N-acetylglucosaminylphosphatidylinositol deacetylase [EC:3.5.1.89] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[M]	Cell wall/membrane/envelope biogenesis	GlcNAc-PI de-N-acetylase	N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase GN=PIGL OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [Ceratotherium simum simum]
ENSG00000108479(GALK1)	--	37.01042	802	31.110987	718	37.868385	834	41.52145	841	47.83528	1002	39.96949	826	0.976684012	0.037600956	normal	0.528835131	0.458579154	normal	0.977265655	-0.022156673	normal	0.466156679	0.160234417	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Molecular Function: galactose binding (GO:0005534);; 	"K00849|0|hsa:2584|GALK1, GALK, GK1, HEL-S-19; galactokinase 1 (EC:2.7.1.6); K00849 galactokinase [EC:2.7.1.6] (A)"	Galactose metabolism (ko00052);; Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	Galactokinase galactose-binding signature;; GHMP kinases C terminal;; GHMP kinases N terminal domain	Galactokinase GN=GALK1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: galactokinase [Oryctolagus cuniculus]
ENSG00000108506(INTS2)	--	11.98398473	1133	13.93529646	1374	12.23108318	1174	10.8139246	1017	12.78492512	1184	12.8267979	1236	0.9632731	-0.186393477	normal	0.951159525	-0.235859524	normal	0.980198269	0.065872188	normal	0.584122188	-0.119680706	normal	--	--	Cellular Component: integrator complex (GO:0032039);; 	"K13139|0|hsa:57508|INTS2, INT2, KIAA1287; integrator complex subunit 2; K13139 integrator complex subunit 2 (A)"	--	--	--	Integrator complex subunit 2	Integrator complex subunit 2 GN=INTS2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: integrator complex subunit 2 isoform X2 [Panthera tigris altaica]
ENSG00000108509(CAMTA2)	--	14.84109438	1315	14.04446727	1235	14.64234992	1312	14.5953969	1272	12.93826552	1133	15.46725126	1368	0.980312621	-0.078702886	normal	0.972334104	-0.145603517	normal	0.981997098	0.051950423	normal	0.834721539	-0.054596929	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	--	--	[S]	Function unknown	CG-1 domain;; IPT/TIG domain;; Ankyrin repeat;; IQ calmodulin-binding motif;; Ankyrin repeat	Calmodulin-binding transcription activator 2 GN=CAMTA2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: calmodulin-binding transcription activator 2 isoform X1 [Bos mutus]
ENSG00000108510(MED13)	--	14.8093977	2545	17.91884575	3099	16.20992303	2759	19.376901	3281	20.58868409	3685	19.863034	3453	0.909241357	0.335458913	normal	0.974492793	0.228333021	normal	0.931740742	0.315258664	normal	0.080091779	0.289170979	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	"K15164|0|hsa:9969|MED13, ARC250, DRIP250, HSPC221, THRAP1, TRAP240; mediator complex subunit 13; K15164 mediator of RNA polymerase II transcription subunit 13 (A)"	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	Mediator complex subunit 13 N-terminal;; Mediator complex subunit 13 C-terminal	Mediator of RNA polymerase II transcription subunit 13 GN=MED13 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 13 isoform X2 [Galeopterus variegatus]
ENSG00000108511(HOXB6)	--	12.48712572	1313	15.29319235	1561	10.76333796	1248	16.75193708	1916	16.9376737	2155	16.20533438	2168	0.280137706	0.513897952	normal	0.620219567	0.443423724	normal	0.000426872	0.787722133	normal	5.21E-05	0.576898947	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09306|7.45292e-117|hsa:3216|HOXB6, HOX2, HOX2B, HU-2, Hox-2.2; homeobox B6; K09306 homeobox protein HoxA/B/C6 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-B6 GN=HOXB6 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: homeobox protein Hox-B6 [Sorex araneus]
ENSG00000108515(ENO3)	--	31.86706542	783	36.49708781	886	28.08885454	718	13.70117424	309	16.57000839	382	13.3412004	326	1.05E-11	-1.367803576	down	1.55E-09	-1.231860345	down	5.78E-08	-1.143733874	down	6.72E-15	-1.252104728	down	[G]	Carbohydrate transport and metabolism	--	"K01689|0|ptr:454457|ENO3; enolase 3 (beta, muscle); K01689 enolase [EC:4.2.1.11] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; RNA degradation (ko03018);; HIF-1 signaling pathway (ko04066)	[G]	Carbohydrate transport and metabolism	"Enolase, C-terminal TIM barrel domain;; Enolase, N-terminal domain;; Methylaspartate ammonia-lyase C-terminus;; Enolase C-terminal domain-like"	Beta-enolase GN=ENO3 OS=Homo sapiens (Human) PE=1 SV=5	G	Carbohydrate transport and metabolism	PREDICTED: beta-enolase isoformX1 [Canis lupus familiaris]
ENSG00000108518(PFN1)	--	1872.28389	23519	2064.86234	26768	1986.79586	25870	2189.82332	27988	1970.93704	24782	1877.56117	24104	0.995261897	0.220136218	normal	0.997445057	-0.132635495	normal	0.997736085	-0.110292237	normal	0.985888279	-0.008128892	normal	--	--	--	"K05759|8.40136e-59|mcc:710753|PFN1, profilin-1; profilin 1; K05759 profilin (A)"	Rap1 signaling pathway (ko04015);; Regulation of actin cytoskeleton (ko04810);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	Profilin	Profilin-1 GN=PFN1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: profilin-1 [Galeopterus variegatus]
ENSG00000108523(RNF167)	--	50.80275773	1519	53.18253667	1641	55.18974439	1651	62.63439959	1872	56.78405226	1704	62.41727739	1902	0.941216629	0.270379596	normal	0.984475257	0.032893791	normal	0.970262111	0.195718529	normal	0.391214295	0.166191486	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K15706|0|hsa:26001|RNF167, 5730408C10Rik, RING105; ring finger protein 167; K15706 E3 ubiquitin-protein ligase RNF167 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; PA domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF167 (Precursor) GN=RNF167 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF167 isoform X1 [Vicugna pacos]
ENSG00000108528(SLC25A11)	--	52.09992048	1346	42.25438	1160	56.44648	1458	44.19409	1142	43.60773001	1120	40.54536	1046	0.933779145	-0.267615914	normal	0.978744434	-0.071957153	normal	0.38805696	-0.486800351	normal	0.100118899	-0.282129374	normal	--	--	--	"K15104|0|pps:100981487|SLC25A11; solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11; K15104 solute carrier family 25 (mitochondrial oxoglutarate transporter), member 11 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial 2-oxoglutarate/malate carrier protein GN=SLC25A11 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: mitochondrial 2-oxoglutarate/malate carrier protein [Galeopterus variegatus]
ENSG00000108551(RASD1)	--	0.271537331	8	0.637022963	19	0.644516127	19	0.1261343	3	0.194608655	5	0.430380148	13	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07843|0|pon:100434987|RASD1; RAS, dexamethasone-induced 1; K07843 RAS, dexamethasone-induced Ras-related protein 1 (A)"	Circadian entrainment (ko04713)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Dexamethasone-induced Ras-related protein 1 (Precursor) GN=RASD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: dexamethasone-induced Ras-related protein 1 isoform X1 [Condylura cristata]
ENSG00000108556(CHRNE)	--	0.557171	22	0.22514	9	0.317508	12	0.375141	15	0.219612	8	0.297525	12	0.980882263	-0.537640362	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04817|0|hsa:1145|CHRNE, ACHRE, CMS1D, CMS1E, CMS2A, FCCMS, SCCMS; cholinergic receptor, nicotinic, epsilon (muscle); K04817 nicotinic acetylcholine receptor epsilon (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Acetylcholine receptor subunit epsilon (Precursor) GN=CHRNE OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: acetylcholine receptor subunit epsilon [Equus caballus]
ENSG00000108557(RAI1)	--	21.18149766	3208	19.5241154	3142	19.76458306	2996	22.056294	3485	22.3698669	3368	18.95711564	2877	0.989451004	0.088611528	normal	0.989306462	0.078745789	normal	0.98913489	-0.066729469	normal	0.894182217	0.036263621	normal	--	--	--	--	--	--	--	PHD-like zinc-binding domain;; PHD-zinc-finger like domain	Retinoic acid-induced protein 1 GN=RAI1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: retinoic acid-induced protein 1 [Galeopterus variegatus]
ENSG00000108559(NUP88)	--	25.76964136	1398	24.12128	1293	28.158937	1485	23.31415063	1253	26.734776	1397	18.98370553	1029	0.966524886	-0.188591129	normal	0.979682191	0.090081812	normal	0.195694915	-0.536850822	normal	0.291560065	-0.204251706	normal	--	--	--	K14318|0|hsa:4927|NUP88; nucleoporin 88kDa; K14318 nuclear pore complex protein Nup88 (A)	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Nuclear pore component	Nuclear pore complex protein Nup88 GN=NUP88 OS=Homo sapiens (Human) PE=1 SV=2	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup88 [Ceratotherium simum simum]
ENSG00000108576(SLC6A4)	--	0.044865312	5	0	0	0.008876677	0	0.026876276	3	0.071447158	6	0.026156057	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Molecular Function: serotonin:sodium symporter activity (GO:0005335);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05037|0|hsa:6532|SLC6A4, 5-HTT, 5-HTTLPR, 5HTT, HTT, OCD1, SERT, SERT1, hSERT; solute carrier family 6 (neurotransmitter transporter), member 4; K05037 solute carrier family 6 (neurotransmitter transporter, serotonin) member 4 (A)"	Serotonergic synapse (ko04726)	[T]	Signal transduction mechanisms	"Sodium:neurotransmitter symporter family;; Serotonin (5-HT) neurotransmitter transporter, N-terminus"	Sodium-dependent serotonin transporter GN=SLC6A4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent serotonin transporter [Ceratotherium simum simum]
ENSG00000108578(BLMH)	--	20.88117408	921	21.83020585	976	22.13261796	960	26.41144485	1175	27.6999442	1209	21.35260367	923	0.881310914	0.320081731	normal	0.917588808	0.28703438	normal	0.97728302	-0.06489094	normal	0.337860627	0.189220521	normal	[E]	Amino acid transport and metabolism	Molecular Function: cysteine-type endopeptidase activity (GO:0004197);; Biological Process: proteolysis (GO:0006508);; 	"K01372|0|hsa:642|BLMH, BH, BMH; bleomycin hydrolase (EC:3.4.22.40); K01372 bleomycin hydrolase [EC:3.4.22.40] (A)"	--	[E]	Amino acid transport and metabolism	Peptidase C1-like family;; Papain family cysteine protease	Bleomycin hydrolase GN=BLMH OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: bleomycin hydrolase [Tupaia chinensis]
ENSG00000108582(CPD)	--	39.88937587	5738	40.31029381	5635	37.86962723	5236	51.47851208	7442	54.59185643	7853	55.2626678	7952	0.939841962	0.344229034	normal	0.72469311	0.457297335	normal	0.103901822	0.594420918	normal	0.003150845	0.463964159	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	K07752|0|pps:100977539|CPD; carboxypeptidase D; K07752 carboxypeptidase D [EC:3.4.17.22] (A)	--	[R]	General function prediction only	Zinc carboxypeptidase;; Carboxypeptidase regulatory-like domain;; Domain of unknown function (DUF4480);; Succinylglutamate desuccinylase / Aspartoacylase family;; PEGA domain	Carboxypeptidase D (Precursor) GN=CPD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carboxypeptidase D isoform X1 [Oryctolagus cuniculus]
ENSG00000108587(GOSR1)	--	20.21949555	1475	18.34533935	1479	19.58198583	1385	21.7783523	1516	24.82356219	1795	21.11337615	1545	0.983989552	0.008713583	normal	0.94776167	0.257695742	normal	0.975361632	0.149275028	normal	0.492780762	0.141242918	normal	--	--	--	K08495|7.20496e-176|pps:100970395|GOSR1; golgi SNAP receptor complex member 1; K08495 golgi SNAP receptor complex member 1 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snare region anchored in the vesicle membrane C-terminus	Golgi SNAP receptor complex member 1 GN=GOSR1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi SNAP receptor complex member 1-like isoform X1 [Tupaia chinensis]
ENSG00000108588(CCDC47)	--	66.393134	3775	71.03236007	4015	66.439159	3688	68.206452	3910	63.33878038	3577	66.493875	3734	0.99185709	0.019851761	normal	0.983059652	-0.188001353	normal	0.991667223	0.009587922	normal	0.835253959	-0.05414097	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1682)	Coiled-coil domain-containing protein 47 (Precursor) GN=CCDC47 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 47 [Physeter catodon] 
ENSG00000108590(MED31)	--	21.22858	299	19.73039	328	19.21001	292	23.26618	336	19.2652	289	21.77671	293	0.959021688	0.136820033	normal	0.943977242	-0.2030547	normal	0.967755723	-0.003341868	normal	0.964587023	-0.023371666	normal	[R]	General function prediction only	"Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Cellular Component: mediator complex (GO:0016592);; "	K15153|2.78289e-82|ptr:468449|MED31; mediator complex subunit 31; K15153 mediator of RNA polymerase II transcription subunit 31 (A)	--	[KL]	"Transcription;; Replication, recombination and repair"	SOH1	Mediator of RNA polymerase II transcription subunit 31 GN=MED31 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 31 [Oryctolagus cuniculus] 
ENSG00000108591(DRG2)	--	18.17807549	686	17.17188869	655	17.07333405	659	21.70864307	807	24.54570105	935	17.43796421	666	0.952136252	0.203108085	normal	0.401241336	0.491091328	normal	0.974843866	0.006936436	normal	0.270702122	0.246215987	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	K06944|0|ptr:743542|DRG2; developmentally regulated GTP binding protein 2; K06944 (A)	--	[T]	Signal transduction mechanisms	TGS domain;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B	Developmentally-regulated GTP-binding protein 2 GN=DRG2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: developmentally-regulated GTP-binding protein 2 isoform X1 [Myotis lucifugus] 
ENSG00000108592(FTSJ3)	--	29.722671	2236	29.063135	2276	29.514612	2391	34.972888	2596	35.08031062	2679	28.489289	2188	0.977476353	0.184420247	normal	0.972173147	0.21363651	normal	0.982801151	-0.136202746	normal	0.688053297	0.091005201	normal	[J]	"Translation, ribosomal structure and biogenesis"	Cellular Component: nucleus (GO:0005634);; Biological Process: rRNA processing (GO:0006364);; Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: methylation (GO:0032259);; 	"K14857|0|hsa:117246|FTSJ3, EPCS3, SPB1; FtsJ homolog 3 (E. coli) (EC:2.1.1.-); K14857 AdoMet-dependent rRNA methyltransferase SPB1 [EC:2.1.1.-] (A)"	--	[AR]	RNA processing and modification;; General function prediction only	Spb1 C-terminal domain;; FtsJ-like methyltransferase;; Domain of unknown function (DUF3381)	pre-rRNA processing protein FTSJ3 {ECO:0000255|HAMAP-Rule:MF_03163} OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: pre-rRNA processing protein FTSJ3 [Ceratotherium simum simum]
ENSG00000108599(AKAP10)	--	14.8742803	990	16.269411	1125	15.052891	992	16.11374168	1003	14.41592431	933	16.6342068	1135	0.97945559	-0.011992597	normal	0.912661668	-0.29097235	normal	0.963362106	0.185723951	normal	0.895946735	-0.037810987	normal	--	--	--	"K16526|0|hsa:11216|AKAP10, AKAP-10, D-AKAP-2, D-AKAP2, PRKA10; A kinase (PRKA) anchor protein 10; K16526 A-kinase anchor protein 10 (A)"	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	"A-kinase anchor protein 10, mitochondrial (Precursor) GN=AKAP10 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: A-kinase anchor protein 10, mitochondrial [Felis catus]"
ENSG00000108602(ALDH3A1)	--	699.6026816	23900	423.070281	14765	654.7702957	22808	359.1467713	12421	353.5673821	12088	307.6730913	10525	8.55E-07	-0.97497295	normal	0.978162649	-0.309997191	normal	1.38E-09	-1.123898658	down	0.011397246	-0.832454535	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00129|0|hsa:218|ALDH3A1, ALDH3, ALDHIII; aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5); K00129 aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Histidine metabolism (ko00340);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; beta-Alanine metabolism (ko00410);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[C]	Energy production and conversion	Aldehyde dehydrogenase family;; Acyl-CoA reductase (LuxC)	"Aldehyde dehydrogenase, dimeric NADP-preferring GN=ALDH3A1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: aldehyde dehydrogenase, dimeric NADP-preferring [Ailuropoda melanoleuca]"
ENSG00000108604(SMARCD2)	--	31.09766009	1630	26.123547	1385	29.10875056	1507	39.04855982	1959	35.22418	1809	30.9966008	1625	0.959431421	0.234211576	normal	0.838593236	0.363531641	normal	0.981234301	0.100371842	normal	0.183977622	0.232412885	normal	[B]	Chromatin structure and dynamics	Molecular Function: protein binding (GO:0005515);; 	"K11650|0|ptr:454776|SMARCD2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2; K11650 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	SWIB/MDM2 domain	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 GN=SMARCD2 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 [Sus scrofa]
ENSG00000108622(ICAM2)	--	0.120275001	2	0.29868205	5	0.116984499	1	0.19394	4	0.644855001	9	0.155586067	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06523|0|hsa:3384|ICAM2, CD102; intercellular adhesion molecule 2; K06523 intercellular adhesion molecule 2 (A)"	Cell adhesion molecules (CAMs) (ko04514);; Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Intercellular adhesion molecule (ICAM), N-terminal domain"	Intercellular adhesion molecule 2 (Precursor) GN=ICAM2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: intercellular adhesion molecule 2 [Ochotona princeps]
ENSG00000108639(SYNGR2)	--	114.0643881	3337	100.1279247	2825	103.2850158	2989	126.6873127	3577	135.9442958	3839	115.118316	3311	0.990328186	0.069335332	normal	0.76007016	0.420859189	normal	0.986044523	0.139245708	normal	0.250884708	0.207869694	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Membrane-associating domain	Synaptogyrin-2 GN=SYNGR2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptogyrin-2 [Orycteropus afer afer]
ENSG00000108641(B9D1)	--	37.39556	467	31.94046	406	33.749497	404	22.06356	276	24.003458	301	22.355173	292	0.004399541	-0.786180335	normal	0.635866038	-0.45118306	normal	0.558373847	-0.474579349	normal	0.005668754	-0.576423598	normal	--	--	--	"K16744|1.3038e-151|hsa:27077|B9D1, B9, EPPB9, MKS9, MKSR1; B9 protein domain 1; K16744 B9 domain-containing protein 1 (A)"	--	[S]	Function unknown	"Ciliary basal body-associated, B9 protein"	B9 domain-containing protein 1 GN=B9D1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: B9 domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000108651(UTP6)	--	12.874445	960	13.459337	985	12.43349266	935	15.30934921	1098	17.014206	1146	13.28113623	901	0.967600062	0.162695883	normal	0.960290474	0.196704659	normal	0.977142569	-0.06162915	normal	0.6515701	0.105226543	normal	[R]	General function prediction only	"Biological Process: maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000462);; Molecular Function: snoRNA binding (GO:0030515);; "	"K14557|0|hsa:55813|UTP6, C17orf40, HCA66; UTP6, small subunit (SSU) processome component, homolog (yeast); K14557 U3 small nucleolar RNA-associated protein 6 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	U3 small nucleolar RNA-associated protein 6	U3 small nucleolar RNA-associated protein 6 homolog GN=UTP6 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U3 small nucleolar RNA-associated protein 6 homolog [Dasypus novemcinctus]
ENSG00000108654(DDX5)	--	293.431408	11551	299.987396	11395	269.0594755	11099	338.529242	12855	371.828202	13870	338.748405	12444	0.99563455	0.12346402	normal	0.986839487	0.262108733	normal	0.994469706	0.156708984	normal	0.400659459	0.18097904	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	K12823|0|umr:103665648|DDX5; DEAD (Asp-Glu-Ala-Asp) box helicase 5; K12823 ATP-dependent RNA helicase DDX5/DBP2 [EC:3.6.4.13] (A)	Spliceosome (ko03040);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205)	[A]	RNA processing and modification	DEAD/DEAH box helicase;; P68HR (NUC004) repeat;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX5 GN=DDX5 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX5 isoform X3 [Canis lupus familiaris]
ENSG00000108666(C17orf75)	--	16.701233	524	14.974276	450	19.53270698	536	15.19224002	458	17.31243862	487	15.10801919	459	0.938897672	-0.22434717	normal	0.966394161	0.092272089	normal	0.936326434	-0.231324247	normal	0.651033402	-0.125948253	normal	--	--	--	--	--	--	--	Mjmu-R1-like protein family	Protein Njmu-R1 GN=C17orf75 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein Njmu-R1 [Ceratotherium simum simum]
ENSG00000108669(CYTH1)	--	22.09921335	1365	18.82240165	1207	18.23347602	1182	19.46813499	1222	18.99967022	1181	16.17132827	1005	0.965684801	-0.19026243	normal	0.980181511	-0.052776418	normal	0.944629374	-0.241989815	normal	0.426711498	-0.161364318	normal	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	K18441|0|cjc:100399565|CYTH1; cytohesin 1; K18441 cytohesin (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; PH domain	Cytohesin-1 GN=CYTH1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: cytohesin-1 isoform X3 [Canis lupus familiaris]
ENSG00000108671(PSMD11)	--	58.382895	3149	62.8651835	3502	63.33394	3290	64.718476	3619	67.00200002	3638	54.002112	2880	0.983980319	0.169787769	normal	0.990977524	0.033525697	normal	0.978536572	-0.200211773	normal	0.985435375	0.006330605	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K03036|0|ptr:454574|PSMD11; proteasome (prosome, macropain) 26S subunit, non-ATPase, 11; K03036 26S proteasome regulatory subunit N6 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	PCI domain	26S proteasome non-ATPase regulatory subunit 11 GN=PSMD11 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 11 [Mustela putorius furo] 
ENSG00000108679(LGALS3BP)	--	53.36213837	2299	53.17712031	2388	54.31471904	2419	157.041883	6655	175.968215	7571	156.4211635	6881	0	1.501982968	up	0	1.642638188	up	0	1.499334921	up	1.96E-30	1.549631479	up	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	"K17300|0|hsa:3959|LGALS3BP, 90K, BTBD17B, CyCAP, M2BP, MAC-2-BP, TANGO10B, gp90; lectin, galactoside-binding, soluble, 3 binding protein; K17300 galectin-3-binding protein (A)"	--	--	--	Scavenger receptor cysteine-rich domain;; BTB And C-terminal Kelch	Galectin-3-binding protein (Precursor) GN=LGALS3BP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: galectin-3-binding protein isoform X1 [Galeopterus variegatus]
ENSG00000108684(ASIC2)	--	0.748426161	45	0.532812808	34	0.702036328	45	0.300308658	19	0.650321224	38	0.355408102	20	0.36540293	-1.209343491	normal	0.980580949	0.133422771	normal	0.501912882	-1.120316147	normal	0.244107962	-0.707822619	normal	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	K04828|0|ptr:748244|ASIC2; acid-sensing ion channel 2; K04828 acid-sensing ion channel 2 (A)	Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Acid-sensing ion channel 2 GN=ASIC2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: acid-sensing ion channel 2 isoformX2 [Canis lupus familiaris]
ENSG00000108691(CCL2)	--	20.153921	206	23.437473	229	17.474258	173	42.235466	428	51.325896	520	46.972444	482	3.11E-05	1.018752723	up	3.65E-07	1.156532373	up	3.07E-11	1.461981377	up	3.19E-10	1.2126846	up	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000108733(PEX12)	--	5.3408063	219	5.4675872	209	6.3579006	232	5.297125	212	6.062155	222	5.656675	245	0.964639487	-0.077148704	normal	0.964161675	0.065172588	normal	0.965114552	0.069921932	normal	0.974731668	0.020348099	normal	--	--	--	"K13345|0|hsa:5193|PEX12, PAF-3, PBD3A; peroxisomal biogenesis factor 12; K13345 peroxin-12 (A)"	Peroxisome (ko04146)	[O]	"Posttranslational modification, protein turnover, chaperones"	Pex2 / Pex12 amino terminal region	Peroxisome assembly protein 12 GN=PEX12 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxisome assembly protein 12 [Galeopterus variegatus]
ENSG00000108759(KRT32)	--	0.0863248	3	0.0280784	1	0.109893	3	0.0573135	2	0.0839081	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3882|KRT32, HA2, HKA2, KRTHA2, hHa2; keratin 32; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cuticular Ha2 GN=KRT32 OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	"PREDICTED: keratin, type I cuticular Ha2 [Galeopterus variegatus]"
ENSG00000108771(DHX58)	--	0.111085903	6	0.035832033	2	0.147784898	3	0.089486356	2	0.044615121	0	0.054885475	3	--	--	--	--	--	--	--	--	--	--	--	--	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K12649|0|hsa:79132|DHX58, D11LGP2, D11lgp2e, LGP2, RLR-3; DEXH (Asp-Glu-X-His) box polypeptide 58 (EC:3.6.4.13); K12649 ATP-dependent RNA helicase DHX58 [EC:3.6.3.14] (A)"	RIG-I-like receptor signaling pathway (ko04622)	[R]	General function prediction only	"C-terminal domain of RIG-I;; Type III restriction enzyme, res subunit;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase"	Probable ATP-dependent RNA helicase DHX58 GN=DHX58 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DHX58 [Galeopterus variegatus]
ENSG00000108773(KAT2A)	--	178.9494923	6380	173.4698826	6285	190.5854803	6928	198.2675049	6791	196.9325147	6885	194.2046988	6780	0.994340962	0.059221521	normal	0.993008525	0.110092037	normal	0.994711989	-0.039436397	normal	0.887313641	0.041169756	normal	[BK]	Chromatin structure and dynamics;; Transcription	"Molecular Function: histone acetyltransferase activity (GO:0004402);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: N-acetyltransferase activity (GO:0008080);; "	"K06062|0|hsa:2648|KAT2A, GCN5, GCN5L2, PCAF-b, hGCN5; K(lysine) acetyltransferase 2A (EC:2.3.1.48); K06062 histone acetyltransferase [EC:2.3.1.48] (A)"	Notch signaling pathway (ko04330);; Thyroid hormone signaling pathway (ko04919);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[BK]	Chromatin structure and dynamics;; Transcription	PCAF (P300/CBP-associated factor) N-terminal domain;; Bromodomain;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) family	Histone acetyltransferase KAT2A GN=KAT2A OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase KAT2A isoformX1 [Canis lupus familiaris]
ENSG00000108784(NAGLU)	--	50.696021	1926	50.9234	2028	40.644389	1689	28.13298416	1123	32.334446	1225	61.88657	2276	0.000235654	-0.808226615	normal	0.001806472	-0.747976752	normal	0.689513095	0.421713354	normal	0.583902742	-0.306659975	normal	--	--	--	"K01205|0|hsa:4669|NAGLU, MPS-IIIB, MPS3B, NAG, UFHSD; N-acetylglucosaminidase, alpha (EC:3.2.1.50); K01205 alpha-N-acetylglucosaminidase [EC:3.2.1.50] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain;; Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain;; Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain	Alpha-N-acetylglucosaminidase 77 kDa form (Precursor) GN=NAGLU OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: alpha-N-acetylglucosaminidase [Physeter catodon]
ENSG00000108786(HSD17B1)	--	1.503732	148	2.172587	190	2.002399955	180	1.454522	142	1.789465823	155	1.7238694	163	0.965584945	-0.089588887	normal	0.911010526	-0.312399477	normal	0.958810659	-0.150090663	normal	0.643252981	-0.192013322	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00044|0|hsa:3292|HSD17B1, EDH17B2, EDHB17, HSD17, SDR28C1; hydroxysteroid (17-beta) dehydrogenase 1 (EC:1.1.1.62); K00044 17beta-estradiol 17-dehydrogenase [EC:1.1.1.62] (A)"	Steroid hormone biosynthesis (ko00140);; Ovarian steroidogenesis (ko04913)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase	Estradiol 17-beta-dehydrogenase 1 GN=HSD17B1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: estradiol 17-beta-dehydrogenase 1 [Galeopterus variegatus]
ENSG00000108788(MLX)	--	21.097398	857	18.834088	784	20.75713847	835	18.332107	757	20.472994	823	17.933538	741	0.951383241	-0.209434322	normal	0.975523255	0.048520867	normal	0.959677901	-0.180247335	normal	0.636377246	-0.114414941	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09113|0|hsa:6945|MLX, MAD7, MXD7, TCFL4, bHLHd13; MLX, MAX dimerization protein; K09113 MAX-like protein X (A)"	Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Max-like protein X GN=MLX OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: max-like protein X isoform X1 [Lipotes vexillifer]
ENSG00000108797(CNTNAP1)	--	8.17821	830	7.67742	786	6.98295	717	5.79756	586	5.54028	559	7.03959	717	0.236194678	-0.531864592	normal	0.331525849	-0.511933513	normal	0.975737232	-0.008273991	normal	0.059501646	-0.346144706	normal	--	--	--	K07379|0|ptr:454696|CNTNAP1; contactin associated protein 1; K07379 contactin associated protein 1 (A)	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; F5/8 type C domain;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain	Contactin-associated protein 1 (Precursor) GN=CNTNAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: contactin-associated protein 1 [Felis catus]
ENSG00000108799(EZH1)	--	7.054577542	770	6.981374343	778	7.786703953	750	5.344633554	582	4.898837615	504	7.7333815	858	0.611888559	-0.433672498	normal	0.039264643	-0.646199326	normal	0.958676859	0.185445766	normal	0.4723875	-0.261458328	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; 	K17451|0|ptr:454697|EZH1; enhancer of zeste 1 polycomb repressive complex 2 subunit; K17451 histone-lysine N-methyltransferase EZH1 [EC:2.1.1.43] (A)	--	[K]	Transcription	SET domain;; WD repeat binding protein EZH2	Histone-lysine N-methyltransferase EZH1 GN=EZH1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: histone-lysine N-methyltransferase EZH1 isoform 2 [Orcinus orca] 
ENSG00000108813(DLX4)	--	3.6226741	146	2.846538764	117	3.356544	138	1.52619952	58	2.079448186	88	2.826355059	122	6.41E-05	-1.339499824	down	0.884241983	-0.425987857	normal	0.957760848	-0.18393336	normal	0.098007254	-0.600244987	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09314|2.01321e-134|pon:100459176|DLX4; distal-less homeobox 4; K09314 homeobox protein DLX1/4/6 (A)	--	[K]	Transcription	Homeobox domain	Homeobox protein DLX-4 GN=DLX4 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: homeobox protein DLX-4 [Galeopterus variegatus]
ENSG00000108819(PPP1R9B)	--	34.66148209	2812	32.47674078	2744	35.76480721	3042	33.44459097	2780	35.27449963	2882	31.04663882	2558	0.989235112	-0.047317972	normal	0.988937824	0.049336764	normal	0.961276456	-0.258155191	normal	0.710502684	-0.086086336	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17551|0|ggo:101130236|PPP1R9B; neurabin-2; K17551 neurabin (A)	--	[T]	Signal transduction mechanisms	PDZ domain (Also known as DHR or GLGF)	Neurabin-2 GN=PPP1R9B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neurabin-2 [Leptonychotes weddellii]
ENSG00000108821(COL1A1)	--	1.108016429	150	0.958579744	132	0.592722	80	3.998680206	424	5.330938	693	2.252749159	281	1.40E-10	1.458997383	up	0	2.357745794	up	1.98E-12	1.785031811	up	0.014368426	1.926670978	normal	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Molecular Function: protein binding (GO:0005515);; 	"K06236|3.15669e-172|ptr:104001053|COL1A1; collagen, type I, alpha 1; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; von Willebrand factor type C domain	Collagen alpha-1(I) chain (Precursor) GN=COL1A1 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	pro alpha 1(I) collagen [Bos taurus]
ENSG00000108823(SGCA)	--	0	0	0	0	0	0	0	0	0.438950029	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: sarcoglycan complex (GO:0016012);; 	"K12565|0|pon:100461016|SGCA; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); K12565 alpha-sarcoglycan (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	[S]	Function unknown	Sarcoglycan alpha/epsilon	Alpha-sarcoglycan (Precursor) GN=SGCA OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"Alpha-sarcoglycan, partial [Pteropus alecto]"
ENSG00000108825(PTGES3L-AARSD1)	--	17.4393697	447	17.0445164	460	17.54284247	465	24.29360832	618	22.87065589	593	22.64489459	579	0.624503579	0.435222684	normal	0.841921864	0.343973366	normal	0.88493501	0.30714432	normal	0.069947211	0.362329252	normal	[R]	General function prediction only	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: alanine-tRNA ligase activity (GO:0004813);; Molecular Function: ATP binding (GO:0005524);; Biological Process: alanyl-tRNA aminoacylation (GO:0006419);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	K07050|0|hsa:100885850|PTGES3L-AARSD1; PTGES3L-AARSD1 readthrough; K07050 misacylated tRNA(Ala) deacylase [EC:3.1.1.-] (A)	--	[R]	General function prediction only	Threonyl and Alanyl tRNA synthetase second additional domain;; tRNA synthetases class II (A);; CS domain	Alanyl-tRNA editing protein Aarsd1 GN=AARSD1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: alanyl-tRNA editing protein Aarsd1 isoform 1 [Ceratotherium simum simum]
ENSG00000108826(MRPL27)	--	64.63701876	687	83.68634254	884	73.70172185	788	71.8861393	785	73.67465916	762	79.01154251	824	0.962705937	0.161212838	normal	0.941662448	-0.235247993	normal	0.975837644	0.056052063	normal	0.971576238	-0.013787207	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02899|1.37092e-88|hsa:51264|MRPL27, L27mt; mitochondrial ribosomal protein L27; K02899 large subunit ribosomal protein L27 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L27 protein	"39S ribosomal protein L27, mitochondrial GN=MRPL27 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L27, mitochondrial [Orycteropus afer afer]"
ENSG00000108828(VAT1)	--	217.3230551	10399	217.3823683	10686	202.2602	10303	176.5004423	8598	176.8140992	8228	243.5553912	11911	0.972571993	-0.305154374	normal	0.903658664	-0.398470313	normal	0.991897964	0.200911171	normal	0.627998163	-0.147583756	normal	[CR]	Energy production and conversion;; General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	"K00540|0|hsa:10493|VAT1, VATI; vesicle amine transport 1 (A)"	--	[CR]	Energy production and conversion;; General function prediction only	Zinc-binding dehydrogenase;; Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	Synaptic vesicle membrane protein VAT-1 homolog GN=VAT1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	synaptic vesicle membrane protein VAT-1 homolog [Bos taurus] 
ENSG00000108829(LRRC59)	--	107.1031536	5252	98.7289	5052	113.4150107	5650	140.0609	6812	145.001947	7027	98.385745	4888	0.935942274	0.34429061	normal	0.719703027	0.454511865	normal	0.983210524	-0.217235452	normal	0.443977174	0.209344366	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 59 GN=LRRC59 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 59 [Tupaia chinensis] 
ENSG00000108830(RND2)	--	0.194054	16	0.2016582	17	0.0876768	6	0.26535	22	0.2576801	20	0.12037	10	0.985280014	0.396064393	normal	0.987844406	0.19687953	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07858|9.29495e-154|ptr:454709|RND2; Rho family GTPase 2; K07858 Rho family GTPase 2 (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoN (Precursor) GN=RND2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoN isoform 2 [Dasypus novemcinctus]
ENSG00000108839(ALOX12)	--	0.022445	1	0.0221543	1	0.065267916	2	0.022457782	1	0.087691806	3	0.0892035	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: protein binding (GO:0005515);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00458|0|hsa:239|ALOX12, 12-LOX, 12S-LOX, LOG12; arachidonate 12-lipoxygenase (EC:1.13.11.31); K00458 arachidonate 12-lipoxygenase [EC:1.13.11.31] (A)"	Arachidonic acid metabolism (ko00590);; Serotonergic synapse (ko04726);; Inflammatory mediator regulation of TRP channels (ko04750)	--	--	Lipoxygenase;; PLAT/LH2 domain	"Arachidonate 12-lipoxygenase, 12S-type GN=ALOX12 OS=Homo sapiens (Human) PE=1 SV=4"	R	General function prediction only	"PREDICTED: arachidonate 12-lipoxygenase, 12S-type-like [Ceratotherium simum simum]"
ENSG00000108840(HDAC5)	--	6.419313346	475	12.33047366	837	5.772063952	418	4.096696413	274	5.729485031	412	12.60235204	879	0.001964739	-0.821039921	normal	1.20E-06	-1.041269778	down	3.75E-07	1.06136069	up	0.902164414	-0.163281326	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	"K11406|0|hsa:10014|HDAC5, HD5, NY-CO-9; histone deacetylase 5 (EC:3.5.1.98); K11406 histone deacetylase 4/5 [EC:3.5.1.98] (A)"	Alcoholism (ko05034);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain;; Glutamine rich N terminal domain of histone deacetylase 4	Histone deacetylase 5 GN=HDAC5 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 5 isoform X1 [Bos mutus]
ENSG00000108846(ABCC3)	--	98.7780449	9831	89.35114	9240	81.11537	8092	89.110584	8868	110.910519	11047	100.108076	9852	0.99221938	-0.179532106	normal	0.98794416	0.236227922	normal	0.979769473	0.275582119	normal	0.643745166	0.111002434	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05667|0|ggo:101145190|ABCC3; canalicular multispecific organic anion transporter 2; K05667 ATP-binding cassette, subfamily C (CFTR/MRP), member 3 (A)"	ABC transporters (ko02010);; Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter transmembrane region;; ABC transporter;; 50S ribosome-binding GTPase	Canalicular multispecific organic anion transporter 2 GN=ABCC3 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: canalicular multispecific organic anion transporter 2 [Pantholops hodgsonii]
ENSG00000108848(LUC7L3)	--	65.38978964	4040	67.48013769	4286	64.6216144	4276	59.06780324	3822	64.67285293	4060	52.01541729	3488	0.989794262	-0.110816439	normal	0.990464097	-0.099542587	normal	0.949368438	-0.302034767	normal	0.385597669	-0.169785284	normal	[A]	RNA processing and modification	Molecular Function: mRNA binding (GO:0003729);; Cellular Component: U1 snRNP (GO:0005685);; Biological Process: mRNA splice site selection (GO:0006376);; 	--	--	[A]	RNA processing and modification	LUC7 N_terminus	Luc7-like protein 3 GN=LUC7L3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: luc7-like protein 3 isoform X1 [Condylura cristata] 
ENSG00000108852(MPP2)	--	4.333290743	342	3.015796655	248	4.699608396	354	3.422797936	274	3.546227944	296	1.595804191	135	0.85096456	-0.348897323	normal	0.935015744	0.232531218	normal	5.51E-09	-1.389096484	down	0.365609344	-0.443564294	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Guanylate kinase;; L27 domain;; Variant SH3 domain;; PDZ domain (Also known as DHR or GLGF);; SH3 domain	MAGUK p55 subfamily member 2 GN=MPP2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: MAGUK p55 subfamily member 2 [Trichechus manatus latirostris]
ENSG00000108854(SMURF2)	--	15.76358163	1131	17.27416339	1103	18.40061143	1242	25.37879416	1865	16.79422761	1169	16.31101583	1211	0.006875919	0.690007524	normal	0.9791776	0.062332562	normal	0.981240799	-0.044702625	normal	0.525092388	0.265807207	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	K04678|0|hsa:64750|SMURF2; SMAD specific E3 ubiquitin protein ligase 2; K04678 E3 ubiquitin ligase SMURF1/2 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain;; C2 domain	E3 ubiquitin-protein ligase SMURF2 GN=SMURF2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: E3 ubiquitin-protein ligase SMURF2 [Vicugna pacos]
ENSG00000108861(DUSP3)	--	36.92435028	2627	43.21879803	3155	38.6314751	2697	43.30875216	3083	39.8912623	2843	47.14597731	3342	0.977376545	0.199978378	normal	0.982128942	-0.171565783	normal	0.941333874	0.300912919	normal	0.62444621	0.107213935	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K17614|1.63839e-135|ptr:468271|DUSP3; dual specificity phosphatase 3; K17614 dual specificity phosphatase 3 [EC:3.1.3.16 3.1.3.48] (A)	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 3 GN=DUSP3 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 3 isoform X2 [Bos taurus]
ENSG00000108878(CACNG1)	--	0.231738	4	0	0	0.166224	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K04866|1.78009e-128|ptr:741106|CACNG1; calcium channel, voltage-dependent, gamma subunit 1; K04866 voltage-dependent calcium channel gamma-1 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	--	--	PMP-22/EMP/MP20/Claudin tight junction;; PMP-22/EMP/MP20/Claudin family	Voltage-dependent calcium channel gamma-1 subunit GN=CACNG1 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent calcium channel gamma-1 subunit [Ceratotherium simum simum]
ENSG00000108883(EFTUD2)	--	58.51520111	4240	54.92446243	3994	59.73892571	4260	63.60701597	4631	69.23252747	4955	56.3374263	4092	0.991249812	0.096393801	normal	0.961099657	0.289525581	normal	0.991689998	-0.066314706	normal	0.623727906	0.109214674	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K12852|0|phd:102322411|EFTUD2; elongation factor Tu GTP binding domain containing 2; K12852 116 kDa U5 small nuclear ribonucleoprotein component (A)	Spliceosome (ko03040)	[J]	"Translation, ribosomal structure and biogenesis"	"Elongation factor Tu GTP binding domain;; Elongation factor G, domain IV;; Elongation factor G C-terminus;; Elongation factor Tu domain 2;; Elongation Factor G, domain II;; Miro-like protein"	116 kDa U5 small nuclear ribonucleoprotein component GN=EFTUD2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 116 kDa U5 small nuclear ribonucleoprotein component [Ovis aries] 
ENSG00000108924(HLF)	--	1.59478941	110	1.28383595	68	0.718515121	42	0.079192288	7	0.484182289	27	0.045348385	4	0	-3.735578468	down	0.029800905	-1.306309512	normal	1.41E-05	-2.987709999	down	0.007367981	-2.555522078	down	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09057|1.47923e-166|pps:100974557|HLF; hepatic leukemia factor; K09057 hepatic leukemia factor (A)	--	[K]	Transcription	Basic region leucine zipper	Hepatic leukemia factor GN=HLF OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: hepatic leukemia factor [Odobenus rosmarus divergens] 
ENSG00000108932(SLC16A6)	--	16.74323706	869	10.47111468	549	12.14406295	593	2.389940181	134	2.658208811	143	4.665905287	250	0	-2.713853858	down	0	-1.950867601	down	5.53E-09	-1.24933371	down	6.78E-06	-1.951554621	down	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08183|0|hsa:9120|SLC16A6, MCT6, MCT7; solute carrier family 16, member 6; K08183 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 6 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 7 GN=SLC16A6 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 7 [Tupaia chinensis]
ENSG00000108946(PRKAR1A)	--	86.83940715	4492	94.1647673	5077	90.89985831	4634	92.90365646	5149	90.85634834	4718	97.5143396	5091	0.988033402	0.166049003	normal	0.990441153	-0.127188087	normal	0.990570963	0.127359913	normal	0.839788434	0.053378532	normal	--	--	--	"K04739|0|ptr:454845|PRKAR1A; protein kinase, cAMP-dependent, regulatory, type I, alpha; K04739 cAMP-dependent protein kinase regulator (A)"	Apoptosis (ko04210);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	Cyclic nucleotide-binding domain;; Regulatory subunit of type II PKA R-subunit	"cAMP-dependent protein kinase type I-alpha regulatory subunit, N-terminally processed GN=PRKAR1A OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	PREDICTED: cAMP-dependent protein kinase type I-alpha regulatory subunit [Oryctolagus cuniculus]
ENSG00000108947(EFNB3)	--	0.934676	51	0.213679	12	0.58264	32	1.28345	70	2.48709	135	1.06907	59	0.941896391	0.415309301	normal	0	3.316578344	up	0.685677037	0.84453719	normal	0.105393481	1.453657503	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K05463|4.58084e-180|hsa:1949|EFNB3, EFL6, EPLG8, LERK8; ephrin-B3; K05463 ephrin-B (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Ephrin	Ephrin-B3 (Precursor) GN=EFNB3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ephrin-B3 [Galeopterus variegatus]
ENSG00000108950(FAM20A)	--	0.1283642	8	0.0559114	4	0.0740489	3	0.0374631	3	0.0536321	2	0.018225	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1193)	Protein FAM20A (Precursor) GN=FAM20A OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: protein FAM20A [Oryctolagus cuniculus]
ENSG00000108953(YWHAE)	--	271.687103	10379	272.7714576	10625	274.9091608	10509	339.10212	13036	320.2918191	12207	276.0300885	10592	0.978709534	0.297962118	normal	0.993259235	0.17879553	normal	0.99640473	0.003057753	normal	0.457854539	0.163625031	normal	--	--	--	"K06630|0|umr:103667175|YWHAE; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon; K06630 14-3-3 protein epsilon (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; Hippo signaling pathway (ko04390);; Neurotrophin signaling pathway (ko04722);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein	14-3-3 protein epsilon GN=YWHAE OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 14-3-3 protein epsilon isoform X1 [Oryctolagus cuniculus] 
ENSG00000108960(MMD)	--	117.304734	3812	88.00054413	2915	89.659706	2905	34.11918402	1133	40.85622911	1332	32.11053516	1051	0	-1.779831678	down	1.16E-09	-1.150421886	down	1.11E-16	-1.473735259	down	1.77E-10	-1.475393674	down	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; 	K11064|3.98868e-177|ptr:455141|MMD; monocyte to macrophage differentiation-associated; K11064 monocyte to macrophage differentiation protein (A)	--	[V]	Defense mechanisms	Haemolysin-III related	Monocyte to macrophage differentiation factor GN=MMD OS=Homo sapiens (Human) PE=2 SV=2	V	Defense mechanisms	PREDICTED: monocyte to macrophage differentiation factor [Orcinus orca]
ENSG00000108961(RANGRF)	--	26.9019	390	30.07953	448	28.4515	415	29.79796	450	27.57549	416	29.47964	447	0.953213438	0.174976504	normal	0.961494177	-0.127893606	normal	0.965857966	0.098526041	normal	0.899311644	0.046191745	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Ran-interacting Mog1 protein	Ran guanine nucleotide release factor GN=RANGRF OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ran guanine nucleotide release factor [Galeopterus variegatus]
ENSG00000108963(DPH1)	--	65.62343932	1406	65.28458379	1373	64.9686718	1415	64.62936435	1416	71.64218661	1540	70.5527917	1610	0.983267266	-0.020585178	normal	0.975620026	0.144022324	normal	0.971187118	0.177788947	normal	0.651857553	0.101855271	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K07561|0|hsa:1801|DPH1, DPH2L, DPH2L1, OVCA1; diphthamide biosynthesis 1; K07561 2-(3-amino-3-carboxypropyl)histidine synthase [EC:2.5.1.108] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Putative diphthamide synthesis protein	Diphthamide biosynthesis protein 1 GN=DPH1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: diphthamide biosynthesis protein 1 [Galeopterus variegatus]
ENSG00000108984(MAP2K6)	--	13.50252544	1024	10.69933303	965	10.37762653	905	13.07049453	1199	15.79408317	1428	21.41613	1876	0.961232736	0.196510993	normal	0.196774197	0.543264579	normal	9.51E-08	1.042142681	up	0.051208347	0.617825006	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04433|0|pps:100972424|MAP2K6; mitogen-activated protein kinase kinase 6; K04433 mitogen-activated protein kinase kinase 6 [EC:2.7.12.2] (A)	MAPK signaling pathway (ko04010);; Rap1 signaling pathway (ko04015);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Toxoplasmosis (ko05145);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Dual specificity mitogen-activated protein kinase kinase 6 GN=MAP2K6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual specificity mitogen-activated protein kinase kinase 6 [Trichechus manatus latirostris]
ENSG00000109016(DHRS7B)	--	10.17329558	258	6.747374327	213	7.689762404	224	8.709056185	242	10.71582436	292	12.46654423	303	0.960558164	-0.122443187	normal	0.741480507	0.431064774	normal	0.74477307	0.425051346	normal	0.417563393	0.247684678	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K11166|0|hsa:25979|DHRS7B, SDR32C1; dehydrogenase/reductase (SDR family) member 7B (EC:1.1.-.-); K11166 dehydrogenase/reductase SDR family member 7B [EC:1.1.-.-] (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; Fungal family of unknown function (DUF1776)	Dehydrogenase/reductase SDR family member 7B GN=DHRS7B OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 7B isoform X2 [Galeopterus variegatus]
ENSG00000109046(WSB1)	--	28.10728553	1238	31.63130875	1380	24.66414591	1131	31.7670405	1406	31.26291248	1282	37.26757801	1621	0.973263249	0.152575256	normal	0.976307267	-0.127553494	normal	0.291071773	0.510420658	normal	0.399726441	0.179761079	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K10341|0|hsa:26118|WSB1, SWIP1, WSB-1; WD repeat and SOCS box containing 1; K10341 WD repeat and SOCS box-containing protein 1 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat;; SOCS box;; Eukaryotic translation initiation factor eIF2A"	WD repeat and SOCS box-containing protein 1 GN=WSB1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat and SOCS box-containing protein 1 isoformX2 [Canis lupus familiaris]
ENSG00000109047(RCVRN)	--	0	0	0.0310137	2	0	0	0	0	0.0154468	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K13764|4.91822e-146|ptr:455078|RCVRN, RCV1; recoverin; K13764 recoverin (A)"	Phototransduction (ko04744)	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF hand;; Cytoskeletal-regulatory complex EF hand	Recoverin GN=RCVRN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: recoverin [Pteropus alecto] 
ENSG00000109062(SLC9A3R1)	--	22.14452417	876	17.8499656	711	19.51211367	808	19.24920472	774	22.80972521	897	17.98352518	725	0.951908951	-0.209039187	normal	0.884763116	0.31323755	normal	0.962840186	-0.164340848	normal	0.954960941	-0.020601981	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13365|0|hsa:9368|SLC9A3R1, EBP50, NHERF, NHERF-1, NHERF1, NPHLOP2; solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1; K13365 Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (A)"	--	[S]	Function unknown	"PDZ domain (Also known as DHR or GLGF);; EBP50, C-terminal;; PDZ domain"	Na(+)/H(+) exchange regulatory cofactor NHE-RF1 GN=SLC9A3R1 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF1 isoform X2 [Galeopterus variegatus]
ENSG00000109063(MYH3)	--	0.467056	79	0.379374	65	0.36238	62	0.247477	42	0.29918	50	0.329437	56	0.311517515	-0.917411847	normal	0.947579076	-0.38957274	normal	0.973742956	-0.151249227	normal	0.347203614	-0.497572614	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10352|0|hsa:4621|MYH3, HEMHC, MYHC-EMB, MYHSE1, SMHCE; myosin, heavy chain 3, skeletal muscle, embryonic; K10352 myosin heavy chain (A)"	Tight junction (ko04530)	[Z]	Cytoskeleton	Myosin tail;; Myosin head (motor domain);; Myosin N-terminal SH3-like domain	Myosin-3 GN=MYH3 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: myosin-3 [Leptonychotes weddellii]
ENSG00000109065(NAT9)	--	20.1797948	633	14.90717472	566	21.52209785	663	20.6090853	611	19.97414601	683	18.08191298	575	0.97106714	-0.081663609	normal	0.930034023	0.249050467	normal	0.946063905	-0.213215652	normal	0.969236371	-0.015669976	normal	--	--	"Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	--	--	[G]	Carbohydrate transport and metabolism	Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) family;; FR47-like protein	N-acetyltransferase 9 GN=NAT9 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: N-acetyltransferase 9 [Galeopterus variegatus]
ENSG00000109066(TMEM104)	--	9.324117879	794	10.56033495	902	10.686333	938	10.8311027	881	10.9466499	925	10.99596476	928	0.971181275	0.118952174	normal	0.977926834	0.014874748	normal	0.978604729	-0.023716117	normal	0.913331578	0.032899733	normal	--	--	--	--	--	[R]	General function prediction only	Transmembrane amino acid transporter protein;; Tryptophan/tyrosine permease family	Transmembrane protein 104 GN=TMEM104 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: transmembrane protein 104 [Camelus ferus]
ENSG00000109072(VTN)	--	7.76877	308	14.875022	593	8.36731	336	6.436458	202	8.863553	351	14.60696343	585	0.154790274	-0.635461429	normal	0.00382576	-0.775386425	normal	0.002501214	0.788959128	normal	0.905275811	-0.139145269	normal	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: immune response (GO:0006955);; Molecular Function: polysaccharide binding (GO:0030247);; 	"K06251|0|hsa:7448|VTN, V75, VN, VNT; vitronectin; K06251 vitronectin (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Proteoglycans in cancer (ko05205)	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Hemopexin;; Somatomedin B domain	Somatomedin-B (Precursor) GN=VTN OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: vitronectin [Galeopterus variegatus]
ENSG00000109079(TNFAIP1)	--	27.3353588	1780	28.36738521	1902	27.04891399	1837	48.0828533	3175	43.7559164	2854	40.15016254	2573	0.000234168	0.80352105	normal	0.149058258	0.563673336	normal	0.462461289	0.47747474	normal	1.02E-05	0.61841774	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: protein homooligomerization (GO:0051260);; 	"K15074|0|nle:100598972|TNFAIP1; tumor necrosis factor, alpha-induced protein 1 (endothelial); K15074 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein (A)"	--	[P]	Inorganic ion transport and metabolism	BTB/POZ domain;; BTB/POZ domain	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 GN=TNFAIP1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 [Tupaia chinensis]
ENSG00000109083(IFT20)	--	29.80252079	414	30.568225	410	31.355173	443	39.518973	567	38.90673	554	38.936085	552	0.67399525	0.421544183	normal	0.711348593	0.411525289	normal	0.884051534	0.308126033	normal	0.061260619	0.379882609	normal	--	--	--	K16473|4.69055e-94|ptr:468195|IFT20; intraflagellar transport 20; K16473 intraflagellar transport protein 20 (A)	--	--	--	"Intraflagellar transport complex B, subunit 20"	Intraflagellar transport protein 20 homolog GN=IFT20 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: intraflagellar transport protein 20 homolog isoform X1 [Tupaia chinensis] 
ENSG00000109084(TMEM97)	--	57.346586	2269	63.1795004	2398	69.82574071	2626	55.97585091	2112	58.55562033	2106	75.0203864	2822	0.982455676	-0.134184828	normal	0.971591984	-0.208612277	normal	0.987386335	0.095506563	normal	0.826804952	-0.071069672	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2781)	Transmembrane protein 97 GN=TMEM97 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 97 [Galeopterus variegatus]
ENSG00000109089(CDR2L)	--	16.7708	1185	17.3102	1243	16.6797	1219	27.4514	1937	26.5835	1872	21.11	1504	0.009382558	0.677411345	normal	0.127018728	0.568760072	normal	0.917174036	0.294485522	normal	0.000404595	0.520924635	normal	--	--	--	--	--	--	--	--	Cerebellar degeneration-related protein 2-like GN=CDR2L OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: cerebellar degeneration-related protein 2-like [Tupaia chinensis]
ENSG00000109099(PMP22)	--	37.02418524	993	45.67892981	1207	40.3993232	1078	34.2233561	928	21.74791204	592	33.96144231	922	0.971959856	-0.128295772	normal	3.26E-07	-1.04726819	down	0.946484508	-0.233455448	normal	0.082808201	-0.446240504	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Peripheral myelin protein 22 GN=PMP22 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: peripheral myelin protein 22 [Orycteropus afer afer]
ENSG00000109103(UNC119)	--	24.52029303	767	21.18233897	714	23.63400203	745	20.98404347	631	22.127854	699	18.98642351	626	0.881446222	-0.311729055	normal	0.973813577	-0.051946973	normal	0.925926019	-0.25879535	normal	0.330286833	-0.207675562	normal	--	--	--	--	--	[UT]	"Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	"GMP-PDE, delta subunit"	Protein unc-119 homolog A GN=UNC119 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein unc-119 homolog A [Leptonychotes weddellii]
ENSG00000109107(ALDOC)	--	18.59622307	644	12.91267065	442	14.65822517	526	10.09343501	309	3.070558861	106	12.94238566	423	5.52E-07	-1.086455169	down	0	-2.065711837	down	0.86988966	-0.321663174	normal	0.062038964	-0.96420834	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: fructose-bisphosphate aldolase activity (GO:0004332);; Biological Process: glycolytic process (GO:0006096);; 	"K01623|0|hsa:230|ALDOC, ALDC; aldolase C, fructose-bisphosphate (EC:4.1.2.13); K01623 fructose-bisphosphate aldolase, class I [EC:4.1.2.13] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Fructose-bisphosphate aldolase class-I	Fructose-bisphosphate aldolase C GN=ALDOC OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: fructose-bisphosphate aldolase C isoform X1 [Myotis brandtii] 
ENSG00000109111(SUPT6H)	--	35.98266116	5356	37.740265	5956	36.8703157	5690	42.09645	6168	42.32424002	6455	43.786226	6730	0.989080301	0.172768331	normal	0.993127463	0.094623702	normal	0.982702121	0.233829204	normal	0.41822782	0.165923335	normal	[K]	Transcription	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	"K11292|0|hsa:6830|SUPT6H, SPT6, SPT6H, emb-5; suppressor of Ty 6 homolog (S. cerevisiae); K11292 transcription elongation factor SPT6 (A)"	--	[A]	RNA processing and modification	SH2 domain;; Holliday-junction resolvase-like of SPT6;; Helix-hairpin-helix motif;; Death-like domain of SPT6;; Helix-turn-helix DNA-binding domain of SPT6;; Acidic N-terminal SPT6;; Tex-like protein N-terminal domain;; S1 RNA binding domain;; SH2 domain	Transcription elongation factor SPT6 GN=SUPT6H OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: transcription elongation factor SPT6 isoform 1 [Canis lupus familiaris]
ENSG00000109113(RAB34)	--	121.026384	3140	118.186685	3162	118.315322	3073	131.7515363	3323	139.293103	3534	113.307633	2923	0.990270334	0.050865276	normal	0.986441799	0.13897522	normal	0.988855102	-0.080448781	normal	0.884742977	0.039472862	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07921|1.16531e-157|hsa:83871|RAB34, RAB39, RAH; RAB34, member RAS oncogene family; K07921 Ras-related protein Rab-34 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-34 GN=RAB34 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-34 isoform X6 [Galeopterus variegatus]
ENSG00000109118(PHF12)	--	17.458891	1542	15.907451	1467	16.30466537	1512	15.0312617	1396	16.831943	1609	16.129696	1539	0.971332752	-0.174153608	normal	0.979736167	0.111758865	normal	0.984163073	0.017226572	normal	0.967825638	-0.01350937	normal	--	--	--	--	--	[R]	General function prediction only	PHD-finger	PHD finger protein 12 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: PHD finger protein 12 isoform X1 [Pteropus alecto] 
ENSG00000109133(TMEM33)	--	25.68136019	1108	27.512865	1106	21.00760092	1049	33.47767402	1458	29.02746502	1302	33.8587439	1385	0.817382901	0.36475848	normal	0.957737204	0.213681977	normal	0.750182867	0.392086412	normal	0.049059048	0.323689005	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Uncharacterised protein family (UPF0121)	Transmembrane protein 33 GN=TMEM33 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 33 [Condylura cristata]
ENSG00000109163(GNRHR)	--	0.03517369	1	0	0	0.141918013	3	0.140247086	4	0.067933081	1	0.034725964	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04280|0|hsa:2798|GNRHR, GNRHR1, GRHR, HH7, LHRHR, LRHR; gonadotropin-releasing hormone receptor; K04280 gonadotropin-releasing hormone receptor (A)"	Neuroactive ligand-receptor interaction (ko04080);; GnRH signaling pathway (ko04912)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Gonadotropin-releasing hormone receptor GN=GNRHR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	gonadotropin-releasing hormone receptor [Equus caballus] 
ENSG00000109171(SLAIN2)	--	10.02920692	720	8.105315461	707	8.690682786	752	8.195263348	725	8.295012513	702	7.465638574	687	0.975581482	-0.020803935	normal	0.974498983	-0.031597914	normal	0.966592417	-0.138422652	normal	0.822074488	-0.064944376	normal	--	--	--	"K16580|0|hsa:57606|SLAIN2, KIAA1458; SLAIN motif family, member 2; K16580 SLAIN motif-containing protein 1/2 (A)"	--	--	--	SLAIN motif-containing family	SLAIN motif-containing protein 2 GN=SLAIN2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	SLAIN motif-containing protein 2 [Bos taurus] 
ENSG00000109180(OCIAD1)	--	76.494907	1578	91.17211313	1737	86.58814473	1641	80.00717855	1655	77.78464588	1535	83.38687138	1728	0.9843873	0.037865748	normal	0.96773845	-0.199600654	normal	0.983953277	0.0661771	normal	0.9074175	-0.032238549	normal	--	--	--	--	--	--	--	Ovarian carcinoma immunoreactive antigen (OCIA)	OCIA domain-containing protein 1 GN=OCIAD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: OCIA domain-containing protein 1 isoform 1 [Dasypus novemcinctus] 
ENSG00000109181(UGT2B10)	--	0	0	0	0	0	0	0	0	0.09244933	2	0.0314597	1	--	--	--	--	--	--	--	--	--	--	--	--	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00699|0|hsa:7365|UGT2B10, UDPGT2B10; UDP glucuronosyltransferase 2 family, polypeptide B10 (EC:2.4.1.17); K00699 glucuronosyltransferase [EC:2.4.1.17] (A)"	Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Steroid hormone biosynthesis (ko00140);; Starch and sucrose metabolism (ko00500);; Retinol metabolism (ko00830);; Porphyrin and chlorophyll metabolism (ko00860);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain	UDP-glucuronosyltransferase 2B10 (Precursor) GN=UGT2B10 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronosyltransferase 2B4-like isoform X3 [Oryctolagus cuniculus]
ENSG00000109184(DCUN1D4)	--	14.635691	849	17.5706387	907	17.07294321	874	13.288511	734	15.90090478	797	13.9582126	717	0.938276558	-0.240348433	normal	0.952895683	-0.207579854	normal	0.90283488	-0.293390153	normal	0.199160767	-0.247649215	normal	--	--	--	"K17824|0|pps:100976278|DCUN1D4; DCN1, defective in cullin neddylation 1, domain containing 4; K17824 DCN1-like protein 4/5 (A)"	--	[S]	Function unknown	Cullin binding	DCN1-like protein 4 GN=DCUN1D4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: DCN1-like protein 4 [Lipotes vexillifer]
ENSG00000109189(USP46)	--	5.558990994	462	5.710512191	439	6.660614208	500	4.896941951	408	5.884987034	446	5.014154116	405	0.943605013	-0.209414246	normal	0.969825966	0.001391457	normal	0.881521405	-0.311249605	normal	0.509001253	-0.175138198	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11842|0|ptr:461329|USP46; ubiquitin specific peptidase 46; K11842 ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 46 GN=USP46 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 46 isoform X1 [Monodelphis domestica] 
ENSG00000109220(CHIC2)	--	4.685235	101	6.3718	133	4.090437	93	4.09513	103	5.493088	110	5.090815	107	0.970843441	-0.002505478	normal	0.934976808	-0.2916961	normal	0.96155256	0.191117275	normal	0.942436071	-0.052720983	normal	--	--	--	--	--	[R]	General function prediction only	Golgin subfamily A member 7/ERF4 family	Cysteine-rich hydrophobic domain-containing protein 2 GN=CHIC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cysteine-rich hydrophobic domain 2 protein [Echinops telfairi]
ENSG00000109255(NMU)	--	1.170357313	11	1.974462205	20	1.245342065	11	0.67527166	7	1.158622058	10	0.934048476	9	--	--	--	0.958018604	-0.921252886	normal	--	--	--	--	--	--	--	--	Biological Process: regulation of smooth muscle contraction (GO:0006940);; 	K05249|3.23381e-89|pps:100988833|NMU; neuromedin U; K05249 neuromedin U (A)	--	--	--	Neuromedin U	Neuromedin-U-25 (Precursor) GN=NMU OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuromedin-U isoform X1 [Physeter catodon]
ENSG00000109265(KIAA1211)	--	2.144451303	286	2.47100096	331	2.096675478	293	2.795534809	345	2.517270184	334	2.856438716	340	0.932459438	0.238580691	normal	0.967451605	-0.008371597	normal	0.944349286	0.205357863	normal	0.658860259	0.141851019	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4592)	Uncharacterized protein KIAA1211 GN=KIAA1211 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein KIAA1211 homolog isoform X2 [Galeopterus variegatus]
ENSG00000109270(LAMTOR3)	--	10.04977954	278	10.89760999	317	8.7349515	219	12.40048511	317	11.84044614	319	14.11773131	393	0.955418431	0.157748862	normal	0.967131048	-0.012294507	normal	0.003059948	0.830964065	normal	0.236866777	0.317034548	normal	--	--	Biological Process: regulation of TOR signaling (GO:0032006);; 	"K04370|4.81765e-85|ptr:461399|LAMTOR3, MAP2K1IP1, MAPKSP1; late endosomal/lysosomal adaptor, MAPK and MTOR activator 3; K04370 mitogen-activated protein kinase kinase 1 interacting protein 1 (A)"	MAPK signaling pathway (ko04010)	--	--	Mitogen-activated protein kinase kinase 1 interacting	Ragulator complex protein LAMTOR3 GN=LAMTOR3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	ragulator complex protein LAMTOR3 [Bos taurus] 
ENSG00000109320(NFKB1)	--	9.331737119	741	11.40069773	920	10.44049375	839	14.1463886	1048	15.17607599	1197	17.7927871	1420	0.467650484	0.468440705	normal	0.829360037	0.357773932	normal	0.001657632	0.749806181	normal	0.014786019	0.531588756	normal	[R]	General function prediction only	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	K02580|0|ptr:461406|NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; K02580 nuclear factor NF-kappa-B p105 subunit (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Cocaine addiction (ko05030);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Inflammatory bowel disease (IBD) (ko05321)	--	--	Rel homology domain (RHD);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Death domain	Nuclear factor NF-kappa-B p50 subunit GN=NFKB1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear factor NF-kappa-B p105 subunit [Ceratotherium simum simum]
ENSG00000109321(AREG)	--	46.6562006	1073	36.77350076	855	44.9087011	1040	38.03050148	896	35.00960077	804	17.46540092	408	0.910188616	-0.290455811	normal	0.971619865	-0.109954876	normal	3.14E-12	-1.354971325	down	0.18980743	-0.516632857	normal	--	--	--	"K09782|2.76178e-123|ptr:461251|AREG, AREGB; amphiregulin; K09782 amphiregulin (A)"	ErbB signaling pathway (ko04012);; Hippo signaling pathway (ko04390)	--	--	--	Amphiregulin (Precursor) GN=AREGB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: amphiregulin-like isoform 2 [Odobenus rosmarus divergens]
ENSG00000109323(MANBA)	--	13.63559024	461	11.60788876	466	10.94733134	404	12.71349747	496	13.95555046	448	20.56746057	699	0.968748698	0.074501706	normal	0.967341377	-0.077999592	normal	0.002067085	0.780397693	normal	0.462966553	0.283391359	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K01192|0|hsa:4126|MANBA, MANB1; mannosidase, beta A, lysosomal (EC:3.2.1.25); K01192 beta-mannosidase [EC:3.2.1.25] (A)"	Other glycan degradation (ko00511);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolases family 2, sugar binding domain;; Glycosyl hydrolases family 2, TIM barrel domain"	Beta-mannosidase (Precursor) GN=MANBA OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: beta-mannosidase [Galeopterus variegatus]
ENSG00000109332(UBE2D3)	--	86.44749363	2414	84.07010525	2729	79.4440921	2520	107.5833099	3249	93.38104276	2829	98.96301863	2985	0.796726115	0.397519033	normal	0.989162735	0.030476637	normal	0.968422889	0.235885545	normal	0.212544083	0.220518348	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K06689|4.65675e-106|ggo:101149953|UBE2D3; ubiquitin-conjugating enzyme E2 D3; K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 D3 GN=UBE2D3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 D2 isoform X2 [Chrysochloris asiatica]
ENSG00000109339(MAPK10)	--	0.271147241	8	0.305971485	4	0.182718504	10	0.910678114	14	0.41759584	16	0.630561333	17	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K04440|0|tup:102475730|MAPK10; mitogen-activated protein kinase 10; K04440 c-Jun N-terminal kinase [EC:2.7.11.24] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Protein processing in endoplasmic reticulum (ko04141);; Wnt signaling pathway (ko04310);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Salmonella infection (ko05132);; Pertussis (ko05133);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family	Mitogen-activated protein kinase 10 GN=MAPK10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 10 isoform 5 [Dasypus novemcinctus] 
ENSG00000109381(ELF2)	--	6.38422799	351	6.4019971	326	7.197712954	340	6.910822584	375	8.67171979	427	7.329433716	399	0.967085919	0.064314918	normal	0.817914936	0.366448255	normal	0.938878447	0.221651586	normal	0.413547487	0.218988189	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09428|0|mcf:102135076|ELF2; E74-like factor 2 (ets domain transcription factor); K09428 E74-like factor 1/2/4 (A)	--	[K]	Transcription	Transcription factor protein N terminal;; Ets-domain	ETS-related transcription factor Elf-2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS-related transcription factor Elf-2 isoform X1 [Galeopterus variegatus] 
ENSG00000109390(NDUFC1)	--	28.348926	261	24.744969	236	22.72155	235	31.42234	307	31.42583	296	28.531519	273	0.945392507	0.202257899	normal	0.899138164	0.30364321	normal	0.944904888	0.206713494	normal	0.428289421	0.237479549	normal	--	--	--	--	--	--	--	"NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial"	"NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial (Precursor) GN=NDUFC1 OS=Homo sapiens (Human) PE=2 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial [Orycteropus afer afer]"
ENSG00000109424(UCP1)	--	0	0	0	0	0	0	0.0834693	2	0.0811274	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08769|0|hsa:7350|UCP1, SLC25A7, UCP; uncoupling protein 1 (mitochondrial, proton carrier); K08769 solute carrier family 25 (mitochondrial uncoupling protein), member 7 (A)"	PPAR signaling pathway (ko03320);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial brown fat uncoupling protein 1 GN=UCP1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: mitochondrial brown fat uncoupling protein 1 [Panthera tigris altaica]
ENSG00000109436(TBC1D9)	--	8.396752093	925	9.578111067	1071	9.524373988	1036	8.17409295	906	6.910666	755	8.840486	964	0.977077526	-0.060672745	normal	0.263434427	-0.524948791	normal	0.974470034	-0.112040804	normal	0.227447974	-0.228999781	normal	--	--	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; GRAM domain	TBC1 domain family member 9 GN=TBC1D9 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: TBC1 domain family member 9 isoform X1 [Orycteropus afer afer]
ENSG00000109445(ZNF330)	--	13.34358505	363	13.61622705	361	14.06455261	387	14.02081402	420	13.52205903	384	16.23180864	479	0.951832815	0.178883193	normal	0.966252037	0.067407106	normal	0.893958732	0.298350838	normal	0.494722325	0.186945001	normal	--	--	Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	NOA36 protein	Zinc finger protein 330 GN=ZNF330 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 330 [Ceratotherium simum simum]
ENSG00000109452(INPP4B)	--	4.988962372	573	5.011427877	611	5.424032862	560	14.87453282	1745	18.354463	2075	11.66686541	1493	0	1.573248897	up	0	1.739959408	up	5.68E-14	1.404009177	up	3.41E-12	1.585523215	up	--	--	--	"K01109|0|pon:100174369|INPP4B; inositol polyphosphate-4-phosphatase, type II, 105kDa (EC:3.1.3.66); K01109 inositol polyphosphate-4-phosphatase [EC:3.1.3.66] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	--	"Type II inositol 3,4-bisphosphate 4-phosphatase GN=INPP4B OS=Homo sapiens (Human) PE=2 SV=4"	T	Signal transduction mechanisms	"PREDICTED: type II inositol 3,4-bisphosphate 4-phosphatase isoform X1 [Tupaia chinensis]"
ENSG00000109458(GAB1)	--	1.758498321	209	2.471968282	252	1.985022043	182	2.215693838	209	2.386172508	226	2.71388989	259	0.966625497	-0.03060726	normal	0.950877581	-0.177402649	normal	0.60938267	0.497241541	normal	0.835366533	0.089128421	normal	--	--	--	K09593|0|pon:100458884|GAB1; GRB2-associated binding protein 1; K09593 GRB2-associated-binding protein 1 (A)	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Neurotrophin signaling pathway (ko04722);; Bacterial invasion of epithelial cells (ko05100);; Proteoglycans in cancer (ko05205);; Renal cell carcinoma (ko05211)	--	--	PH domain;; Pleckstrin homology domain	GRB2-associated-binding protein 1 GN=GAB1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: GRB2-associated-binding protein 1 isoform 1 [Trichechus manatus latirostris]
ENSG00000109466(KLHL2)	--	7.643081938	389	9.566977634	478	9.600994044	499	7.763757489	401	7.209800479	346	7.825383031	397	0.969516589	0.012949444	normal	0.496540178	-0.485849942	normal	0.852043603	-0.337044462	normal	0.239088943	-0.2769398	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10443|0|hsa:11275|KLHL2, ABP-KELCH, MAV, MAYVEN; kelch-like family member 2; K10443 kelch-like protein 2/3 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain"	Kelch-like protein 2 GN=KLHL2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000109472(CPE)	--	5.165952009	204	3.862499859	141	5.033305082	200	7.698801314	308	8.887260208	351	6.990021264	277	0.36165102	0.560074468	normal	1.58E-07	1.285320304	up	0.68883129	0.458635345	normal	0.001051013	0.759201172	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	K01294|0|hsa:1363|CPE; carboxypeptidase E (EC:3.4.17.10); K01294 carboxypeptidase E [EC:3.4.17.10] (A)	Type I diabetes mellitus (ko04940)	[R]	General function prediction only	Zinc carboxypeptidase;; Carboxypeptidase regulatory-like domain	Carboxypeptidase E (Precursor) GN=CPE OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carboxypeptidase E [Oryctolagus cuniculus]
ENSG00000109475(RPL34)	--	638.5880475	1891	637.7364052	1920	633.1108911	1931	763.5084062	2501	752.8211468	2230	638.6503081	2010	0.834685084	0.372259707	normal	0.973114503	0.194368682	normal	0.98609957	0.049517882	normal	0.240112277	0.209571909	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02915|3.53487e-67|umr:103661731|RPL34; ribosomal protein L34; K02915 large subunit ribosomal protein L34e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L34e	60S ribosomal protein L34 GN=RPL34 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L34 isoform X1 [Mustela putorius furo] 
ENSG00000109501(WFS1)	--	18.82840508	1241	18.825965	1250	21.23265563	1422	15.826309	1039	17.5369052	1152	16.030765	1058	0.91755157	-0.286751102	normal	0.973449057	-0.139038651	normal	0.610297132	-0.434335747	normal	0.089489568	-0.28912203	normal	--	--	--	K14020|0|ggo:101140111|WFS1; wolframin; K14020 wolfamin (A)	Protein processing in endoplasmic reticulum (ko04141)	--	--	--	Wolframin GN=WFS1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: wolframin [Galeopterus variegatus]
ENSG00000109511(ANXA10)	--	2.306016166	52	1.283605746	29	3.400723	73	11.59940413	265	13.288021	297	9.867756116	224	0	2.285437903	up	0	3.269486745	up	6.46E-09	1.589476273	up	3.08E-18	2.331263513	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	"K17097|0|hsa:11199|ANXA10, ANX14; annexin A10; K17097 annexin A10 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A10 GN=ANXA10 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A10-like [Tupaia chinensis]
ENSG00000109519(GRPEL1)	--	15.999	758	14.5951	695	15.5944	736	17.2342	825	16.9821	802	11.8788	565	0.973237834	0.091186815	normal	0.957240913	0.184788147	normal	0.748877282	-0.388831712	normal	0.966060173	-0.020182052	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: adenyl-nucleotide exchange factor activity (GO:0000774);; Biological Process: protein folding (GO:0006457);; Molecular Function: protein homodimerization activity (GO:0042803);; Molecular Function: chaperone binding (GO:0051087);; 	"K03687|5.4903e-118|ptr:471135|GRPEL1; GrpE-like 1, mitochondrial (E. coli); K03687 molecular chaperone GrpE (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	GrpE	"GrpE protein homolog 1, mitochondrial (Precursor) GN=GRPEL1 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: grpE protein homolog 1, mitochondrial [Tupaia chinensis]"
ENSG00000109534(GAR1)	--	16.7633	309	20.79763	404	19.13792	358	26.80734	520	25.11432	459	23.4976	439	0.015342534	0.717294838	normal	0.955578382	0.162142596	normal	0.905303531	0.28488141	normal	0.076258876	0.383120843	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Biological Process: ribosome biogenesis (GO:0042254);; 	K11128|1.38421e-59|pon:100453663|GAR1; GAR1 ribonucleoprotein; K11128 H/ACA ribonucleoprotein complex subunit 1 (A)	Ribosome biogenesis in eukaryotes (ko03008)	[J]	"Translation, ribosomal structure and biogenesis"	Gar1/Naf1 RNA binding region	H/ACA ribonucleoprotein complex subunit 1 GN=GAR1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: H/ACA ribonucleoprotein complex subunit 1 isoform X1 [Galeopterus variegatus] 
ENSG00000109536(FRG1)	--	13.2866777	249	13.8700535	263	14.22848286	267	19.01370826	369	19.17089088	355	13.63043201	256	0.386596214	0.5339211	normal	0.757677518	0.409297192	normal	0.965355235	-0.068590582	normal	0.241247076	0.309045796	normal	--	--	"Molecular Function: protein binding, bridging (GO:0030674);; Molecular Function: actin filament binding (GO:0051015);; "	K13122|2.41939e-162|ptr:738279|FRG1; protein FRG1; K13122 protein FRG1 (A)	--	[Z]	Cytoskeleton	FRG1-like family;; Fascin domain	Protein FRG1 GN=FRG1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	protein FRG1 [Bos taurus] 
ENSG00000109572(CLCN3)	--	15.85954331	1217	17.16164595	1331	15.62003337	1213	21.6089041	1522	23.836469	1490	20.34025964	1520	0.919577854	0.291477323	normal	0.975509108	0.141223489	normal	0.895272225	0.316846739	normal	0.157326009	0.247726568	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05012|0|ptr:471346|CLCN3; chloride channel, voltage-sensitive 3; K05012 chloride channel 3/4/5 (A)"	--	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	H(+)/Cl(-) exchange transporter 3 GN=CLCN3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: H(+)/Cl(-) exchange transporter 3 isoform X2 [Oryctolagus cuniculus] 
ENSG00000109576(AADAT)	--	5.33795168	249	5.067796006	234	4.49646075	204	7.346336299	306	6.561152875	288	7.044229667	312	0.921861133	0.265076162	normal	0.916178693	0.27652044	normal	0.236115883	0.601056393	normal	0.151177229	0.377763196	normal	[KE]	Transcription;; Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00825|0|hsa:51166|AADAT, KAT2, KATII; aminoadipate aminotransferase (EC:2.6.1.7 2.6.1.39); K00825 kynurenine/2-aminoadipate aminotransferase [EC:2.6.1.7 2.6.1.39] (A)"	Lysine biosynthesis (ko00300);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Aminotransferase class I and II;; Alanine-glyoxylate amino-transferase	"Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial (Precursor) GN=AADAT OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: kynurenine/alpha-aminoadipate aminotransferase, mitochondrial [Oryctolagus cuniculus]"
ENSG00000109586(GALNT7)	--	20.39908546	1492	23.95262436	1758	20.71543027	1489	22.91074414	1677	23.21914171	1669	27.06992627	1969	0.977882057	0.137669122	normal	0.982199118	-0.096292646	normal	0.764539095	0.394478423	normal	0.478669535	0.144573323	normal	--	--	--	"K00710|0|hsa:51809|GALNT7, GALNAC-T7, GalNAcT7; polypeptide N-acetylgalactosaminyltransferase 7 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2	N-acetylgalactosaminyltransferase 7 GN=GALNT7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: N-acetylgalactosaminyltransferase 7 [Orycteropus afer afer]
ENSG00000109606(DHX15)	--	58.9105	3236	61.2695	3381	66.0081	3592	60.4535	3331	60.4161	3300	54.3303	2972	0.990860863	0.010906379	normal	0.990123274	-0.056385021	normal	0.955289809	-0.281514171	normal	0.617050764	-0.10964852	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	K12820|0|mdo:100011218|DHX15; DEAH (Asp-Glu-Ala-His) box helicase 15; K12820 pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15/PRP43 [EC:3.6.4.13] (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 GN=DHX15 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 [Monodelphis domestica]
ENSG00000109610(SOD3)	--	0	0	0.047046303	1	0	0	0	0	0.04577947	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: superoxide metabolic process (GO:0006801);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K16627|2.75774e-151|ptr:461143|SOD3; superoxide dismutase 3, extracellular; K16627 superoxide dismutase, Cu-Zn family [EC:1.15.1.1] (A)"	--	[P]	Inorganic ion transport and metabolism	Copper/zinc superoxide dismutase (SODC)	Extracellular superoxide dismutase [Cu-Zn] (Precursor) GN=SOD3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: extracellular superoxide dismutase [Cu-Zn] [Ceratotherium simum simum]
ENSG00000109618(SEPSECS)	--	2.243628965	174	1.844937263	144	2.6147511	163	2.202523292	173	2.2693883	177	3.167165135	246	0.966790444	-0.0388039	normal	0.93083536	0.273657934	normal	0.382751632	0.581076799	normal	0.413547487	0.289215747	normal	[E]	Amino acid transport and metabolism	Molecular Function: transferase activity (GO:0016740);; 	"K03341|0|hsa:51091|SEPSECS, LP, PCH2D, SLA, SLA/LP; Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase (EC:2.9.1.2); K03341 O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase [EC:2.9.1.2] (A)"	Selenocompound metabolism (ko00450);; Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen)	O-phosphoseryl-tRNA(Sec) selenium transferase GN=SEPSECS OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: O-phosphoseryl-tRNA(Sec) selenium transferase [Vicugna pacos]
ENSG00000109625(CPZ)	--	0.202658996	8	0.0466679	2	0	0	0.274972055	11	0.3223955	13	0.099826789	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	K13022|0|hsa:8532|CPZ; carboxypeptidase Z; K13022 carboxypeptidase Z [EC:3.4.17.-] (A)	--	[R]	General function prediction only	Zinc carboxypeptidase;; Fz domain;; Carboxypeptidase regulatory-like domain	Carboxypeptidase Z (Precursor) GN=CPZ OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carboxypeptidase Z [Tupaia chinensis]
ENSG00000109654(TRIM2)	--	0.109619854	11	0.089927212	10	0.415296018	22	0.798793293	78	0.935831196	105	1.604072262	94	1.39E-08	2.636840483	up	4.97E-14	3.189906676	up	6.55E-07	2.01431226	up	4.76E-10	2.66837582	up	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K11997|0|nle:100601906|TRIM2; tripartite motif containing 2; K11997 tripartite motif-containing protein 2/3 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"NHL repeat;; Filamin/ABP280 repeat;; SMP-30/Gluconolaconase/LRE-like region;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; RING-type zinc-finger"	Tripartite motif-containing protein 2 GN=TRIM2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 2 isoform X1 [Loxodonta africana]
ENSG00000109667(SLC2A9)	--	0	0	0.033867652	1	0.134481096	3	0.120952979	3	0.135169633	3	0.104234771	2	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08146|0|pps:100993664|SLC2A9; solute carrier family 2 (facilitated glucose transporter), member 9; K08146 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 9 (A)"	--	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 9 GN=SLC2A9 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 9 isoform X1 [Balaenoptera acutorostrata scammoni]"
ENSG00000109670(FBXW7)	--	4.576402235	331	4.249823724	338	3.336463877	326	3.133807504	310	4.824923565	336	5.062979165	408	0.960744279	-0.124796516	normal	0.967183547	-0.029854599	normal	0.882252171	0.314100716	normal	0.873172277	0.06269106	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10260|0|mcf:102135696|FBXW7; F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase; K10260 F-box and WD-40 domain protein 7 (A)"	Ubiquitin mediated proteolysis (ko04120)	[R]	General function prediction only	"WD domain, G-beta repeat;; Nucleoporin Nup120/160;; F-box-like;; F-box domain"	F-box/WD repeat-containing protein 7 GN=FBXW7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/WD repeat-containing protein 7-like isoform X1 [Camelus ferus] 
ENSG00000109674(NEIL3)	--	11.964	483	12.8632	517	13.1738	522	10.0471	405	7.31846	295	8.49473	343	0.904934518	-0.28394559	normal	0.00164762	-0.827626954	normal	0.101958162	-0.611929226	normal	0.003633372	-0.567008369	normal	[L]	"Replication, recombination and repair"	"Molecular Function: damaged DNA binding (GO:0003684);; Molecular Function: DNA-(apurinic or apyrimidinic site) lyase activity (GO:0003906);; Biological Process: nucleotide-excision repair (GO:0006289);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799);; "	"K10569|0|hsa:55247|NEIL3, FGP2, FPG2, NEI3, ZGRF3, hFPG2, hNEI3; nei endonuclease VIII-like 3 (E. coli) (EC:4.2.99.18); K10569 endonuclease VIII-like 3 (A)"	Base excision repair (ko03410)	--	--	GRF zinc finger;; Formamidopyrimidine-DNA glycosylase H2TH domain;; Zn-finger in Ran binding protein and others	Endonuclease 8-like 3 GN=NEIL3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: endonuclease 8-like 3 [Galeopterus variegatus]
ENSG00000109680(TBC1D19)	--	3.134050245	140	2.903951168	119	4.674023308	201	3.517712505	165	3.92136701	193	2.985755501	149	0.952002222	0.204141602	normal	0.264795673	0.669472205	normal	0.79466451	-0.436347003	normal	0.818502798	0.119847551	normal	--	--	--	--	--	--	--	Rab-GTPase-TBC domain	TBC1 domain family member 19 GN=TBC1D19 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: TBC1 domain family member 19 isoform X1 [Ursus maritimus]
ENSG00000109685(NSD2)	--	34.63618711	3973	37.01558786	4108	34.07441209	4313	36.32887691	4107	34.5404485	3943	32.63664136	3943	0.992186013	0.017017418	normal	0.990843966	-0.080538763	normal	0.988695366	-0.137638954	normal	0.782633671	-0.068658232	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11424|0|hsa:7468|WHSC1, MMSET, NSD2, REIIBP, TRX5, WHS; Wolf-Hirschhorn syndrome candidate 1 (EC:2.1.1.43); K11424 histone-lysine N-methyltransferase NSD2 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	PWWP domain;; SET domain;; PHD-finger;; HMG (high mobility group) box	Histone-lysine N-methyltransferase NSD2 GN=WHSC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone-lysine N-methyltransferase NSD2 isoform X3 [Tupaia chinensis]
ENSG00000109686(SH3D19)	--	10.2737655	1058	10.72938129	1095	11.75939394	1233	11.0578134	1135	10.74561366	1098	11.05110768	1099	0.978763998	0.070421663	normal	0.980058635	-0.017455299	normal	0.967561954	-0.174046609	normal	0.87495885	-0.044244412	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	SH3 domain;; Variant SH3 domain;; Variant SH3 domain	SH3 domain-containing protein 19 GN=SH3D19 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SH3 domain-containing protein 19 isoform X2 [Equus przewalskii]
ENSG00000109689(STIM2)	--	5.284314547	268	5.599798852	281	7.83719416	316	5.62796387	296	6.27870291	297	4.36628305	257	0.961876466	0.111921237	normal	0.965203999	0.058161763	normal	0.896779215	-0.304827012	normal	0.911866656	-0.046558348	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K18196|0|ptr:461155|STIM2; stromal interaction molecule 2; K18196 stromal interaction molecule 2 (A)	Calcium signaling pathway (ko04020)	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Stromal interaction molecule 2 (Precursor) GN=STIM2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: stromal interaction molecule 2 isoform X1 [Lipotes vexillifer]
ENSG00000109705(NKX3-2)	--	0.250054	11	0.173463	8	0.465181	21	0.268086	12	0.28427	12	0.356846	16	--	--	--	--	--	--	0.985773403	-0.370000054	normal	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09995|1.118e-135|hsa:579|NKX3-2, BAPX1, NKX3.2, NKX3B, SMMD; NK3 homeobox 2; K09995 homeobox protein Nkx-3.2 (A)"	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-3.2 GN=NKX3-2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein Nkx-3.2 [Eptesicus fuscus]
ENSG00000109736(MFSD10)	--	53.328512	1236	48.59090169	1186	48.92348261	1199	53.9373058	1260	52.42419362	1201	56.96354818	1330	0.982061236	-0.003083477	normal	0.981137283	-0.003290248	normal	0.974320191	0.141134061	normal	0.871830381	0.045128844	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Major Facilitator Superfamily;; Sugar (and other) transporter	Major facilitator superfamily domain-containing protein 10 GN=MFSD10 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: major facilitator superfamily domain-containing protein 10 [Ceratotherium simum simum]
ENSG00000109738(GLRB)	--	4.009601841	145	4.579490859	172	4.681076122	170	4.88326354	215	5.012566453	195	4.886235859	212	0.581845149	0.532788994	normal	0.955775952	0.158330948	normal	0.910582955	0.307781635	normal	0.319102191	0.331811489	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05196|0|hsa:2743|GLRB, HKPX2; glycine receptor, beta; K05196 glycine receptor beta (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Glycine receptor subunit beta (Precursor) GN=GLRB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: glycine receptor subunit beta isoform X2 [Canis lupus familiaris] 
ENSG00000109743(BST1)	--	5.046688619	139	6.276027445	172	5.370214839	161	12.32360766	338	11.21370357	308	9.850082085	291	4.93E-07	1.242027959	up	0.010918298	0.813678004	normal	0.007286539	0.839716991	normal	2.33E-05	0.967625927	normal	--	--	Molecular Function: NAD+ nucleosidase activity (GO:0003953);; 	"K18152|0|hsa:683|BST1, CD157; bone marrow stromal cell antigen 1 (EC:3.2.2.6); K18152 ADP-ribosyl cyclase 2 [EC:3.2.2.6 2.4.99.20] (A)"	Nicotinate and nicotinamide metabolism (ko00760);; Salivary secretion (ko04970);; Pancreatic secretion (ko04972)	--	--	ADP-ribosyl cyclase	ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2 (Precursor) GN=BST1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ADP-ribosyl cyclase 2 [Ceratotherium simum simum]
ENSG00000109756(RAPGEF2)	--	8.831967774	899	7.623980356	829	6.608362229	832	9.941926388	1132	8.494914021	1000	8.724514444	865	0.901166619	0.30118913	normal	0.93741528	0.248715829	normal	0.976808053	0.047740055	normal	0.295475642	0.205324687	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K08018|0|ptr:461577|RAPGEF2; Rap guanine nucleotide exchange factor (GEF) 2; K08018 Rap guanine nucleotide exchange factor 2 (A)	MAPK signaling pathway (ko04010);; Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; Ras association (RalGDS/AF-6) domain;; PDZ domain (Also known as DHR or GLGF);; Cyclic nucleotide-binding domain	Rap guanine nucleotide exchange factor 2 GN=RAPGEF2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rap guanine nucleotide exchange factor 2 isoform X1 [Canis lupus familiaris] 
ENSG00000109758(HGFAC)	--	0.185460969	7	0.1346392	5	0.05058896	1	0.1115935	4	0.027653416	0	0.168794994	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	"K09631|0|hsa:3083|HGFAC, HGFA; HGF activator (EC:3.4.21.-); K09631 hepatocyte growth factor activator [EC:3.4.21.-] (A)"	--	[T]	Signal transduction mechanisms	Trypsin;; Kringle domain;; Fibronectin type II domain;; Fibronectin type I domain;; EGF-like domain	Hepatocyte growth factor activator long chain (Precursor) GN=HGFAC OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: hepatocyte growth factor activator isoform X2 [Galeopterus variegatus]
ENSG00000109762(SNX25)	--	3.855786193	272	4.886298177	347	4.551971932	318	4.876315943	340	4.382579534	305	4.946456491	345	0.905651076	0.289630112	normal	0.942909999	-0.206591825	normal	0.962927814	0.108781371	normal	0.884468846	0.058182951	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K17887|0|hsa:83891|SNX25, SBBI31; sorting nexin 25; K17887 sorting nexin-25 (A)"	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	Sorting nexin C terminal;; PXA domain;; Regulator of G protein signaling domain;; PX domain	Sorting nexin-25 GN=SNX25 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-25 [Vicugna pacos]
ENSG00000109771(LRP2BP)	--	0.2224716	20	0.4267063	37	0.450957615	23	0.3137014	18	0.180060214	14	0.300189913	24	0.988883247	-0.169132097	normal	0.397957786	-1.331869002	normal	0.98721493	0.049897209	normal	0.495051374	-0.535465287	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[MOT]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Sel1 repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	LRP2-binding protein GN=LRP2BP OS=Homo sapiens (Human) PE=1 SV=2	MOT	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: LRP2-binding protein [Ceratotherium simum simum]
ENSG00000109775(UFSP2)	--	9.773091414	270	8.816635684	237	10.96467568	304	8.741985801	236	8.32810974	233	7.28190416	199	0.939788107	-0.22364226	normal	0.965109166	-0.045689622	normal	0.205196773	-0.615779408	normal	0.303687291	-0.301151566	normal	--	--	--	--	--	[S]	Function unknown	Peptidase family C78	Ufm1-specific protease 2 GN=UFSP2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ufm1-specific protease 2 [Pteropus alecto]
ENSG00000109787(KLF3)	--	8.255239	670	8.167391	668	7.270743	591	8.696627	711	10.060397	819	10.755648	898	0.973955151	0.054734353	normal	0.919111953	0.272031791	normal	0.084691172	0.594024024	normal	0.09738041	0.31122902	normal	[R]	General function prediction only	--	K15605|0|ptr:461165|KLF3; Kruppel-like factor 3 (basic); K15605 krueppel-like factor 3 (A)	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 3 GN=KLF3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: Krueppel-like factor 3 [Ochotona princeps]
ENSG00000109790(KLHL5)	--	51.5891533	3324	61.613919	4129	52.68844538	3416	46.80537783	3159	47.122906	3200	60.669407	4165	0.988523848	-0.104235277	normal	0.848303709	-0.388984751	normal	0.961068752	0.277605607	normal	0.853525777	-0.067110153	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10442|0|pps:100972829|KLHL5; kelch-like family member 5; K10442 kelch-like protein 1/4/5 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 5 GN=KLHL5 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	"Kelch-like protein 5, partial [Bos mutus]"
ENSG00000109794(FAM149A)	--	1.286877419	56	0.808818876	40	1.295302382	59	1.49194953	64	2.010849207	90	1.472399167	65	0.973572004	0.157762051	normal	0.039147676	1.119567787	normal	0.973893741	0.128299191	normal	0.360398524	0.47813986	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3719)	Protein FAM149A GN=FAM149A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	Protein FAM149A [Pteropus alecto]
ENSG00000109805(NCAPG)	--	15.6073704	1222	16.6782771	1219	17.635139	1347	18.99903315	1322	14.36373624	1114	13.009307	1048	0.979866394	0.082545834	normal	0.971277755	-0.151179174	normal	0.803869695	-0.369930429	normal	0.500461306	-0.142448005	normal	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	--	"K06678|0|hsa:64151|NCAPG, CAPG, CHCG, NY-MEL-3, YCG1; non-SMC condensin I complex, subunit G; K06678 condensin complex subunit 3 (A)"	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	"Nuclear condensing complex subunits, C-term domain;; HEAT repeats;; HEAT repeat;; HEAT-like repeat"	Condensin complex subunit 3 GN=NCAPG OS=Homo sapiens (Human) PE=1 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: condensin complex subunit 3 [Galeopterus variegatus]
ENSG00000109814(UGDH)	--	151.2570206	6579	178.7649262	7611	148.9004165	6475	197.19037	8784	211.5197701	8755	219.768433	9502	0.902170794	0.386099213	normal	0.99107975	0.180561129	normal	0.298214482	0.544953879	normal	0.030348921	0.366804015	normal	[M]	Cell wall/membrane/envelope biogenesis	"Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00012|0|ptr:471171|UGDH; UDP-glucose 6-dehydrogenase; K00012 UDPglucose 6-dehydrogenase [EC:1.1.1.22] (A)	Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520)	[GT]	Carbohydrate transport and metabolism;; Signal transduction mechanisms	"UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain;; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain;; UDP-glucose/GDP-mannose dehydrogenase family, central domain"	UDP-glucose 6-dehydrogenase GN=UGDH OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucose 6-dehydrogenase isoformX1 [Canis lupus familiaris] 
ENSG00000109819(PPARGC1A)	--	0.123264903	5	0.008980306	1	0	0	0.071028623	8	0.152975481	16	0.395695851	45	--	--	--	--	--	--	1.04E-09	4.938801562	up	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K07202|0|hsa:10891|PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; K07202 alpha peroxisome proliferator-activated receptor gamma coactivator 1-alpha (A)"	AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Huntington's disease (ko05016)	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Peroxisome proliferator-activated receptor gamma coactivator 1-alpha GN=PPARGC1A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: peroxisome proliferator-activated receptor gamma coactivator 1-alpha isoform X1 [Equus caballus] 
ENSG00000109832(DDX25)	--	0.157644197	1	0	0	0	0	0.007871338	1	0	0	0.041961172	1	--	--	--	--	--	--	--	--	--	--	--	--	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K18656|0|hsa:29118|DDX25, GRTH; DEAD (Asp-Glu-Ala-Asp) box helicase 25 (EC:3.6.4.13); K18656 ATP-dependent RNA helicase DDX25 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	ATP-dependent RNA helicase DDX25 GN=DDX25 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX25 [Ailuropoda melanoleuca]
ENSG00000109846(CRYAB)	--	0.200384681	3	1.17888093	15	0.645400049	2	0.613046575	6	0.865046956	8	1.22345095	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural constituent of eye lens (GO:0005212);; 	"K09542|5.58758e-123|pon:100172850|CRYAB; crystallin, alpha B; K09542 crystallin, alpha B (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Alpha crystallin A chain, N terminal;; Hsp20/alpha crystallin family"	Alpha-crystallin B chain GN=CRYAB OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: alpha-crystallin B chain [Pteropus alecto] 
ENSG00000109854(HTATIP2)	--	95.63092871	1906	88.42877249	1840	85.28234613	1633	93.34794828	1928	86.40867179	1755	92.89840038	1865	0.986428892	-0.014263899	normal	0.983149646	-0.089585891	normal	0.972575826	0.183200536	normal	0.938716194	0.023071249	normal	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	--	"K17290|0|hsa:10553|HTATIP2, CC3, SDR44U1, TIP30; HIV-1 Tat interactive protein 2, 30kDa (EC:1.1.1.-); K17290 oxidoreductase [EC:1.1.1.-] (A)"	--	[T]	Signal transduction mechanisms	"NADH(P)-binding;; Semialdehyde dehydrogenase, NAD binding domain"	Oxidoreductase HTATIP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oxidoreductase HTATIP2 [Orcinus orca]
ENSG00000109861(CTSC)	--	68.59514346	2150	64.03863379	1840	64.57074448	1915	67.88065022	2082	79.11599775	2344	54.91419408	1767	0.985824103	-0.077142829	normal	0.904873822	0.327601182	normal	0.981267912	-0.124231631	normal	0.873246221	0.047111983	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	K01275|0|pps:100987211|CTSC; cathepsin C; K01275 cathepsin C [EC:3.4.14.1] (A)	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin C exclusion domain;; Peptidase C1-like family	Dipeptidyl peptidase 1 light chain (Precursor) GN=CTSC OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dipeptidyl peptidase 1 [Bos mutus] 
ENSG00000109881(CCDC34)	--	19.87743	834	21.234602	930	21.78345468	922	16.779854	729	13.159101	567	16.622671	692	0.945148928	-0.224517995	normal	0.004754531	-0.733763934	normal	0.650502842	-0.421485325	normal	0.006301723	-0.455547076	normal	--	--	--	"K16753|2.88685e-129|hsa:91057|CCDC34, NY-REN-41, RAMA3; coiled-coil domain containing 34; K16753 coiled-coil domain-containing protein 34 (A)"	--	--	--	Domain of unknown function (DUF4207)	Coiled-coil domain-containing protein 34 GN=CCDC34 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 34 [Odobenus rosmarus divergens]
ENSG00000109911(ELP4)	--	16.2510267	366	13.82122708	359	15.44774017	419	12.3404361	357	13.4205014	346	12.51683987	354	0.96693332	-0.066469293	normal	0.965388311	-0.074319439	normal	0.926343481	-0.25050743	normal	0.659319307	-0.135066647	normal	--	--	Cellular Component: Elongator holoenzyme complex (GO:0033588);; 	"K11375|0|hsa:26610|ELP4, AN, C11orf19, PAX6NEB, PAXNEB, dJ68P15A.1, hELP4; elongator acetyltransferase complex subunit 4; K11375 elongator complex protein 4 (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	PAXNEB protein	Elongator complex protein 4 GN=ELP4 OS=Homo sapiens (Human) PE=1 SV=2	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: elongator complex protein 4 [Sus scrofa]
ENSG00000109917(ZPR1)	--	9.883861274	624	9.11661149	598	11.08495112	653	10.12424503	627	11.37758223	729	9.771501525	609	0.973875842	-0.023854256	normal	0.922509813	0.26374186	normal	0.968833021	-0.108671539	normal	0.884742977	0.046583521	normal	[R]	General function prediction only	Molecular Function: zinc ion binding (GO:0008270);; 	"K06874|0|hsa:8882|ZPR1, ZNF259; ZPR1 zinc finger; K06874 zinc finger protein (A)"	--	[R]	General function prediction only	ZPR1 zinc-finger domain	Zinc finger protein ZPR1 GN=ZPR1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein ZPR1 [Tupaia chinensis]
ENSG00000109919(MTCH2)	--	63.44184744	1852	64.99108491	1830	66.02701473	1921	69.99364602	2027	62.06917935	1851	66.91174611	1894	0.98372953	0.099350929	normal	0.985733226	-0.004961235	normal	0.986231429	-0.028689884	normal	0.944803244	0.021526805	normal	--	--	--	K17885|0|ptr:744096|MTCH2; mitochondrial carrier 2; K17885 mitochondrial carrier (A)	--	[R]	General function prediction only	Mitochondrial carrier protein	Mitochondrial carrier homolog 2 GN=MTCH2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial carrier homolog 2 [Ochotona princeps]
ENSG00000109920(FNBP4)	--	17.702343	1352	19.11667698	1505	19.39627	1467	17.077828	1316	20.482588	1610	18.66018	1432	0.981159008	-0.06968765	normal	0.982256694	0.075796998	normal	0.983139855	-0.043083866	normal	0.978492587	-0.009534559	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	WW domain	Formin-binding protein 4 GN=FNBP4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: formin-binding protein 4 [Ceratotherium simum simum]
ENSG00000109927(TECTA)	--	0.03739026	5	0.038711129	6	0.031787715	4	0	0	0.014537496	1	0.038641928	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell-matrix adhesion (GO:0007160);; 	"K18273|0|hsa:7007|TECTA, DFNA12, DFNA8, DFNB21; tectorin alpha; K18273 alpha-tectorin (A)"	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type D domain;; C8 domain;; Zona pellucida-like domain;; Nidogen-like;; Trypsin Inhibitor like cysteine rich domain;; TILa domain	Alpha-tectorin (Precursor) GN=TECTA OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: alpha-tectorin [Felis catus]
ENSG00000109929(SC5D)	--	18.81792729	789	24.1236065	1006	22.927211	945	10.061803	435	10.27661035	446	16.60160243	754	9.17E-05	-0.887477863	normal	3.64E-09	-1.192172503	down	0.858021024	-0.333442535	normal	0.012712717	-0.764374713	normal	[I]	Lipid transport and metabolism	Molecular Function: iron ion binding (GO:0005506);; Biological Process: lipid biosynthetic process (GO:0008610);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00227|0|hsa:6309|SC5D, ERG3, S5DES, SC5DL; sterol-C5-desaturase (EC:1.14.21.6); K00227 lathosterol oxidase [EC:1.14.21.6] (A)"	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	Fatty acid hydroxylase superfamily	Lathosterol oxidase GN=SC5D OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: lathosterol oxidase isoform X1 [Pteropus alecto] 
ENSG00000109943(CRTAM)	--	0.025691217	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16361|0|hsa:56253|CRTAM, CD355; cytotoxic and regulatory T cell molecule; K16361 cytotoxic and regulatory T-cell molecule (A)"	--	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Cytotoxic and regulatory T-cell molecule (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cytotoxic and regulatory T-cell molecule [Galeopterus variegatus]
ENSG00000109944(C11orf63)	--	2.65563995	130	2.16288994	130	1.967090905	93	2.092126943	107	2.854561	121	2.366042579	99	0.933176316	-0.307716915	normal	0.963119538	-0.123442269	normal	0.969818419	0.080635337	normal	0.813356228	-0.132266823	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4591)	Uncharacterized protein C11orf63 GN=C11orf63 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C11orf63 homolog isoform X2 [Galeopterus variegatus]
ENSG00000109971(HSPA8)	--	614.420428	28311	652.9058782	30049	731.9023623	33163	791.112838	36465	589.8220936	26731	530.0934904	23995	0.984969285	0.3343014	normal	0.996533862	-0.190219572	normal	0.835662368	-0.475106566	normal	0.813067828	-0.092289548	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	K03283|0|umr:103662283|HSPA8; heat shock 70kDa protein 8; K03283 heat shock 70kDa protein 1/8 (A)	Spliceosome (ko03040);; MAPK signaling pathway (ko04010);; Protein processing in endoplasmic reticulum (ko04141);; Endocytosis (ko04144);; Antigen processing and presentation (ko04612);; Estrogen signaling pathway (ko04915);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Measles (ko05162);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein;; MreB/Mbl protein	Heat shock cognate 71 kDa protein GN=HSPA8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock cognate 71 kDa protein isoform X1 [Chrysochloris asiatica]
ENSG00000110002(VWA5A)	--	2.031914633	81	1.3346018	55	1.413442718	59	0.492309035	18	0.723335253	29	0.732268452	30	1.34E-06	-2.108194757	down	0.626477806	-0.909783152	normal	0.516984453	-0.949302505	normal	0.00326787	-1.360367464	down	--	--	--	--	--	--	--	von Willebrand factor type A domain;; Vault protein inter-alpha-trypsin domain;; von Willebrand factor type A domain;; Vault protein inter-alpha-trypsin domain;; von Willebrand factor type A domain	von Willebrand factor A domain-containing protein 5A GN=VWA5A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: von Willebrand factor A domain-containing protein 5A-like [Ceratotherium simum simum]
ENSG00000110011(DNAJC4)	--	39.94876194	727	31.38890475	581	36.09492544	705	32.52068	622	38.150776	701	38.71111	719	0.927420975	-0.255289013	normal	0.930526755	0.248859293	normal	0.975518967	0.020034516	normal	1	9.05E-05	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09524|6.85524e-130|mcf:102128323|DNAJC4; DnaJ (Hsp40) homolog, subfamily C, member 4; K09524 DnaJ homolog subfamily C member 4 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 4 GN=DNAJC4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 4 [Galeopterus variegatus]
ENSG00000110013(SIAE)	--	9.740780212	678	7.80425702	583	9.959472864	728	11.34437389	798	10.75276041	745	9.229391738	698	0.951710513	0.203845075	normal	0.859331121	0.331555515	normal	0.973678219	-0.068856764	normal	0.519581419	0.150796989	normal	--	--	--	K05970|0|pps:100990394|SIAE; sialic acid acetylesterase; K05970 sialate O-acetylesterase [EC:3.1.1.53] (A)	--	--	--	Domain of unknown function (DUF303)	Sialate O-acetylesterase (Precursor) GN=SIAE OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sialate O-acetylesterase isoform X1 [Galeopterus variegatus]
ENSG00000110025(SNX15)	--	12.66611379	470	11.1153422	412	13.23210642	474	14.45954382	511	14.24426	490	13.91133115	547	0.967793504	0.089549485	normal	0.936437592	0.227942867	normal	0.948931705	0.19777449	normal	0.511298928	0.170196871	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17927|0|pps:100970178|SNX15; sorting nexin 15; K17927 sorting nexin-15 (A)	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	MIT (microtubule interacting and transport) domain;; PX domain	Sorting nexin-15 GN=SNX15 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-15 isoform X1 [Galeopterus variegatus]
ENSG00000110031(LPXN)	--	2.413902982	79	1.750458857	67	2.101094082	73	3.705627	92	4.51398124	111	3.2100417	106	0.96540687	0.185601787	normal	0.528187531	0.694601808	normal	0.830471756	0.520802302	normal	0.278712874	0.475999123	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	Leupaxin GN=LPXN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: leupaxin, partial [Galeopterus variegatus]"
ENSG00000110042(DTX4)	--	2.824103711	324	2.398399946	277	3.074375523	353	3.774283627	425	3.47581451	394	3.66096439	413	0.827050733	0.359145939	normal	0.543302562	0.48465411	normal	0.940513732	0.217320603	normal	0.139291545	0.34796344	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K06058|0|ptr:451210|DTX4; deltex 4, E3 ubiquitin ligase; K06058 deltex (A)"	Notch signaling pathway (ko04330)	--	--	"WWE domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase DTX4 GN=DTX4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase DTX4 [Oryctolagus cuniculus]
ENSG00000110046(ATG2A)	--	6.787630163	849	5.993379653	713	6.124829671	795	8.592592057	1033	8.489632268	1049	8.767991056	1020	0.935932277	0.251757978	normal	0.233231835	0.534673848	normal	0.832178828	0.350660601	normal	0.02566563	0.375102996	normal	--	--	--	K17906|0|hsa:23130|ATG2A; autophagy related 2A; K17906 autophagy-related protein 2 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"ATG C terminal domain;; N-terminal region of Chorein, a TM vesicle-mediated sorter"	Autophagy-related protein 2 homolog A GN=ATG2A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: autophagy-related protein 2 homolog A [Leptonychotes weddellii]
ENSG00000110047(EHD1)	--	26.19098276	1807	23.25350671	1590	28.07381655	1963	38.88354732	2549	31.07636713	1946	27.87688315	1863	0.517905579	0.465168156	normal	0.943740351	0.269826076	normal	0.984499969	-0.083657775	normal	0.405540116	0.22439543	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; 	K12483|0|pps:100995602|EHD1; EH-domain containing 1; K12483 EH domain-containing protein 1 (A)	Endocytosis (ko04144)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Dynamin family;; Cytoskeletal-regulatory complex EF hand;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	EH domain-containing protein 1 GN=EHD1 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: EH domain-containing protein 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000110048(OSBP)	--	18.3422	1803	17.3545	1728	18.0724	1783	20.6517	2036	21.6364	2110	22.6077	2220	0.979710844	0.144390068	normal	0.947890731	0.266501861	normal	0.920068551	0.307727179	normal	0.167109206	0.239691629	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Oxysterol-binding protein;; PH domain;; Pleckstrin homology domain;; Pleckstrin homology domain	Oxysterol-binding protein 1 GN=OSBP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein 1 [Mustela putorius furo]
ENSG00000110057(UNC93B1)	--	59.82583905	2182	64.74251109	2454	50.48540873	1936	34.44040913	1283	39.70171217	1451	30.27061026	1120	0.000314853	-0.796221749	normal	0.000709842	-0.778882479	normal	0.000340036	-0.797042648	normal	3.44E-06	-0.791789622	normal	--	--	--	--	--	[S]	Function unknown	Ion channel regulatory protein UNC-93	Protein unc-93 homolog B1 GN=UNC93B1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein unc-93 homolog B1 [Orcinus orca]
ENSG00000110060(PUS3)	--	3.766510165	106	3.38338169	92	3.232133736	92	3.922151099	127	3.086743944	84	4.993786359	117	0.953552332	0.226923987	normal	0.965929476	-0.150088049	normal	0.930731168	0.333637296	normal	0.780439538	0.155906633	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	K01855|0|ptr:740256|PUS3; pseudouridylate synthase 3; K01855 tRNA pseudouridine38/39 synthase [EC:5.4.99.45] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	tRNA pseudouridine synthase	tRNA pseudouridine(38/39) synthase GN=PUS3 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA pseudouridine(38/39) synthase isoform X1 [Leptonychotes weddellii]
ENSG00000110063(DCPS)	--	9.706071707	434	8.357141	373	10.70290612	443	8.297121247	337	7.237097815	337	7.306202019	312	0.762045801	-0.394190175	normal	0.953200266	-0.167140288	normal	0.409490988	-0.511958651	normal	0.114630689	-0.363466221	normal	[S]	Function unknown	Biological Process: deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0000290);; Molecular Function: hydrolase activity (GO:0016787);; 	"K12584|0|hsa:28960|DCPS, DCS1, HINT-5, HINT5, HSL1; decapping enzyme, scavenger (EC:3.6.1.59); K12584 m7GpppX diphosphatase [EC:3.6.1.59] (A)"	RNA degradation (ko03018)	[S]	Function unknown	Scavenger mRNA decapping enzyme C-term binding;; Scavenger mRNA decapping enzyme (DcpS) N-terminal	m7GpppX diphosphatase GN=DCPS OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: m7GpppX diphosphatase isoform X1 [Equus caballus] 
ENSG00000110066(KMT5B)	--	8.681847	605	10.13780044	683	7.217137	545	7.457785168	556	10.096968	654	8.068633714	559	0.961283653	-0.152278944	normal	0.971198908	-0.083831789	normal	0.972514257	0.028223282	normal	0.807334114	-0.072677044	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11429|0|pps:100995372|SUV420H1; suppressor of variegation 4-20 homolog 1 (Drosophila); K11429 histone-lysine N-methyltransferase SUV420H [EC:2.1.1.43] (A)	Lysine degradation (ko00310)	[B]	Chromatin structure and dynamics	SET domain	Histone-lysine N-methyltransferase SUV420H1 GN=SUV420H1 OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase SUV420H1 isoform X1 [Galeopterus variegatus]
ENSG00000110074(FOXRED1)	--	11.62110756	421	12.01310549	445	11.32271128	417	13.288817	485	11.966456	430	11.25310627	408	0.954329328	0.172744553	normal	0.967439525	-0.070650964	normal	0.969357721	-0.039624392	normal	0.957636091	0.022476361	normal	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K18166|0|hsa:55572|FOXRED1, H17; FAD-dependent oxidoreductase domain containing 1; K18166 FAD-dependent oxidoreductase domain-containing protein 1 (A)"	--	[R]	General function prediction only	FAD dependent oxidoreductase;; FAD binding domain	FAD-dependent oxidoreductase domain-containing protein 1 GN=FOXRED1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: FAD-dependent oxidoreductase domain-containing protein 1 [Orycteropus afer afer]
ENSG00000110075(PPP6R3)	--	37.60126438	3000	40.53640757	3150	35.98686154	2957	35.84594269	2908	34.8092921	2864	34.20718578	2771	0.98891253	-0.075728099	normal	0.98358172	-0.158666968	normal	0.987525391	-0.101965094	normal	0.598083532	-0.113640329	normal	--	--	--	"K15501|0|hsa:55291|PPP6R3, C11orf23, PP6R3, SAP190, SAPL, SAPLa, SAPS3; protein phosphatase 6, regulatory subunit 3; K15501 serine/threonine-protein phosphatase 6 regulatory subunit 3 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	SIT4 phosphatase-associated protein	Serine/threonine-protein phosphatase 6 regulatory subunit 3 GN=PPP6R3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein phosphatase 6 regulatory subunit 3 isoform X1 [Camelus ferus] 
ENSG00000110076(NRXN2)	--	0.092391646	2	0.066093198	4	0.016030167	0	0.049140091	3	0.069586752	4	0.081158264	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K07377|0|hsa:9379|NRXN2; neurexin 2; K07377 neurexin (A)	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain;; Syndecan domain	Neurexin-2 (Precursor) GN=NRXN2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neurexin-2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000110080(ST3GAL4)	--	10.87727104	346	9.844343779	321	10.78792835	336	8.9320891	299	8.818668702	290	9.05627678	306	0.93155062	-0.240309601	normal	0.952685069	-0.167118177	normal	0.958300714	-0.142548446	normal	0.539707827	-0.185466671	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03494|0|hsa:6484|ST3GAL4, CGS23, NANTA3, SAT3, SIAT4, SIAT4C, ST3GalIV, STZ; ST3 beta-galactoside alpha-2,3-sialyltransferase 4 (EC:2.4.99.4); K03494 beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4C) [EC:2.4.99.4] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 GN=ST3GAL4 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 isoform 1 [Odobenus rosmarus divergens] "
ENSG00000110090(CPT1A)	--	39.4739619	3852	33.73941907	3481	39.33140157	3922	24.74446909	2509	25.82718042	2478	22.13920275	2160	0.019654369	-0.649004042	normal	0.360692796	-0.511487439	normal	2.65E-05	-0.868391624	normal	1.30E-06	-0.676615993	normal	--	--	"Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	K08765|0|pps:100969017|CPT1A; carnitine palmitoyltransferase 1A (liver); K08765 carnitine O-palmitoyltransferase 1 [EC:2.3.1.21] (A)	Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; AMPK signaling pathway (ko04152);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	Choline/Carnitine o-acyltransferase	"Carnitine O-palmitoyltransferase 1, liver isoform GN=CPT1A OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: carnitine O-palmitoyltransferase 1, liver isoform [Felis catus] "
ENSG00000110092(CCND1)	--	108.89687	7782	118.39408	8547	126.034822	9077	124.534982	8951	113.802046	8117	87.2901	6277	0.991989636	0.171044119	normal	0.99454846	-0.095880655	normal	0.314219469	-0.540322904	normal	0.579236144	-0.144084503	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	"K06625|0|ptr:747442|CCND1, CDKN1A; cyclin D1; K04503 cyclin D1 (A)"	ErbB signaling pathway (ko04012);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Oxytocin signaling pathway (ko04921);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G1/S-specific cyclin-D1 GN=CCND1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: G1/S-specific cyclin-D1 [Galeopterus variegatus]
ENSG00000110104(CCDC86)	--	31.6990028	1403	34.74190262	1545	36.33200535	1643	31.43330908	1392	30.2461058	1336	26.58500768	1188	0.982730006	-0.042141729	normal	0.955846767	-0.230870119	normal	0.440812092	-0.475571972	normal	0.150131731	-0.250894125	normal	--	--	--	K14822|0|hsa:79080|CCDC86; coiled-coil domain containing 86; K14822 rRNA-processing protein CGR1 (A)	--	--	--	Cgr1 family	Coiled-coil domain-containing protein 86 GN=CCDC86 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 86 [Galeopterus variegatus]
ENSG00000110107(PRPF19)	--	70.73866653	2509	76.09688123	2615	77.41812454	2722	84.16902605	3113	77.43211568	2788	72.65801687	2534	0.95129712	0.280206558	normal	0.988012918	0.070953314	normal	0.986174051	-0.111477778	normal	0.721622195	0.082711504	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein ubiquitination (GO:0016567);; 	K10599|0|tup:102488278|PRPF19; pre-mRNA processing factor 19; K10599 pre-mRNA-processing factor 19 [EC:6.3.2.19] (A)	Spliceosome (ko03040);; Ubiquitin mediated proteolysis (ko04120)	[R]	General function prediction only	"WD domain, G-beta repeat;; Prp19/Pso4-like;; U-box domain;; Eukaryotic translation initiation factor eIF2A;; Nucleoporin Nup120/160;; Cytochrome D1 heme domain"	Pre-mRNA-processing factor 19 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	pre-mRNA-processing factor 19 [Bos taurus] 
ENSG00000110108(TMEM109)	--	44.6931	1584	45.5635	1719	47.4322	1745	54.5608	1943	50.7966	1806	48.955	1733	0.946116392	0.263650085	normal	0.984611487	0.049759081	normal	0.985473591	-0.01823097	normal	0.662652306	0.097528548	normal	--	--	--	--	--	--	--	Negative regulator of p53/TP53	Transmembrane protein 109 (Precursor) GN=TMEM109 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 109 isoform X1 [Oryctolagus cuniculus]
ENSG00000110169(HPX)	--	0.0741607	2	0.0746798	2	0.356132094	10	0.388172	9	0.261986104	7	0.076227332	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Hemopexin	Hemopexin (Precursor) GN=HPX OS=Homo sapiens (Human) PE=1 SV=2	OW	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	PREDICTED: hemopexin [Tupaia chinensis] 
ENSG00000110171(TRIM3)	--	7.68608841	450	8.030636204	476	8.955124691	515	7.006015216	392	6.531516635	368	7.300604153	417	0.936013788	-0.229064794	normal	0.766406664	-0.3912643	normal	0.880697368	-0.311797012	normal	0.162301981	-0.312809801	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: intracellular (GO:0005622);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; Molecular Function: metal ion binding (GO:0046872);; 	K11997|0|ptr:450993|TRIM3; tripartite motif containing 3; K11997 tripartite motif-containing protein 2/3 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"NHL repeat;; Filamin/ABP280 repeat;; SMP-30/Gluconolaconase/LRE-like region;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Beta-propeller repeat"	Tripartite motif-containing protein 3 GN=TRIM3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 3 isoform X1 [Ochotona princeps] 
ENSG00000110172(CHORDC1)	--	29.2793284	1280	38.83671188	1695	46.41400405	1957	40.15918979	1738	29.17137418	1258	31.687145	1392	0.707462327	0.410028222	normal	0.571007102	-0.451110827	normal	0.34277674	-0.499316198	normal	0.632235429	-0.190163166	normal	--	--	--	K16729|0|ptr:466743|CHORDC1; cysteine and histidine-rich domain (CHORD) containing 1; K16729 cysteine and histidine-rich domain-containing protein 1 (A)	--	[R]	General function prediction only	CHORD;; CS domain	Cysteine and histidine-rich domain-containing protein 1 GN=CHORDC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cysteine and histidine-rich domain-containing protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000110195(FOLR1)	--	0.12032926	2	0.119070261	2	0	0	0.058919975	1	0.29251404	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13649|6.64879e-161|hsa:2348|FOLR1, FBP, FOLR; folate receptor 1 (adult); K13649 folate receptor (A)"	Endocytosis (ko04144)	--	--	Folate receptor family	Folate receptor alpha (Precursor) GN=FOLR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: folate receptor alpha [Galeopterus variegatus] 
ENSG00000110200(ANAPC15)	--	24.0022955	376	30.7506308	480	27.0750107	440	29.811521	462	27.2724359	413	26.26767325	421	0.917705762	0.265348401	normal	0.932250725	-0.23751157	normal	0.968080627	-0.071722694	normal	0.961668997	-0.021508248	normal	--	--	Cellular Component: anaphase-promoting complex (GO:0005680);; Biological Process: regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266);; 	--	--	--	--	Anaphase-promoting complex subunit 15	Anaphase-promoting complex subunit 15 GN=ANAPC15 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: anaphase-promoting complex subunit 15 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000110203(FOLR3)	--	0.08459073	1	0	0	0	0	0.718300089	1	0.096368776	0	0.1781313	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13649|3.74251e-169|hsa:2352|FOLR3, FR-G, FR-gamma, gamma-hFR; folate receptor 3 (gamma); K13649 folate receptor (A)"	Endocytosis (ko04144)	--	--	Folate receptor family	Folate receptor gamma (Precursor) GN=FOLR3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: folate receptor beta [Camelus ferus] 
ENSG00000110218(PANX1)	--	8.620050817	784	9.705297217	818	7.638184404	702	8.231452048	757	9.56601	837	8.789948	777	0.973696308	-0.081230596	normal	0.976775451	0.011678877	normal	0.967045421	0.137869711	normal	0.955958996	0.020051812	normal	--	--	Cellular Component: gap junction (GO:0005921);; 	"K03443|0|hsa:24145|PANX1, MRS1, PX1, UNQ2529; pannexin 1; K03443 pannexin (A)"	--	--	--	Innexin	Pannexin-1 GN=PANX1 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: pannexin-1 [Galeopterus variegatus]
ENSG00000110237(ARHGEF17)	--	8.302515	1202	7.115075	1125	7.95625	1125	6.67879	1053	9.343122	1372	7.712568	1197	0.953651798	-0.221460991	normal	0.936577127	0.264606386	normal	0.978907794	0.081101004	normal	0.860679073	0.048589862	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Rho guanine nucleotide exchange factor 17 GN=ARHGEF17 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 17 [Lipotes vexillifer]
ENSG00000110274(CEP164)	--	4.961808181	633	5.810050492	662	4.665477116	615	5.341944139	633	5.79401491	637	5.658196109	613	0.973848528	-0.030757608	normal	0.971367991	-0.076785566	normal	0.973942811	-0.012958861	normal	0.897663663	-0.041911381	normal	--	--	--	K16462|0|pps:100986117|CEP164; centrosomal protein 164kDa; K16462 centrosomal protein CEP164 (A)	--	--	--	WW domain	Centrosomal protein of 164 kDa GN=CEP164 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: centrosomal protein of 164 kDa [Equus przewalskii]
ENSG00000110315(RNF141)	--	16.37986553	798	16.85754924	797	16.5286029	678	13.680006	642	10.73354787	585	12.25036247	678	0.838367967	-0.343907762	normal	0.505627172	-0.466531919	normal	0.975097914	-0.008272989	normal	0.159552511	-0.276158771	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 141 GN=RNF141 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 141 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000110318(CEP126)	--	1.839750379	283	2.471461668	290	2.119957533	308	2.808652	422	2.375106537	366	2.535854	389	0.318712855	0.543179511	normal	0.885954469	0.312908891	normal	0.870748238	0.327116126	normal	0.088175077	0.396534703	normal	--	--	Cellular Component: centrosome (GO:0005813);; Biological Process: mitotic spindle organization (GO:0007052);; Biological Process: cytoplasmic microtubule organization (GO:0031122);; Cellular Component: ciliary base (GO:0097546);; 	--	--	--	--	Susceptibility to monomelic amyotrophy	Uncharacterized protein KIAA1377 GN=KIAA1377 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein KIAA1377 homolog [Ceratotherium simum simum]
ENSG00000110321(EIF4G2)	--	293.3549026	19308	297.1678234	19210	303.4450824	19820	398.6173381	26355	429.9729683	27999	358.9545915	23885	0.927074674	0.418017126	normal	0.649907306	0.522056997	normal	0.991642578	0.260838318	normal	0.031533449	0.402085657	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	"K03260|0|pale:102879210|EIF4G2; eukaryotic translation initiation factor 4 gamma, 2; K03260 translation initiation factor 4G (A)"	RNA transport (ko03013);; Viral myocarditis (ko05416)	[J]	"Translation, ribosomal structure and biogenesis"	MIF4G domain;; eIF4-gamma/eIF5/eIF2-epsilon;; MA3 domain	Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4 gamma 2 [Bison bison bison]
ENSG00000110324(IL10RA)	--	0.0264886	2	0.0130773	1	0	0	0.0133473	1	0.0129314	0	0.039448	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05134|0|hsa:3587|IL10RA, CD210, CD210a, CDW210A, HIL-10R, IL-10R1, IL10R; interleukin 10 receptor, alpha; K05134 interleukin 10 receptor alpha (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Epstein-Barr virus infection (ko05169)	--	--	"Tissue factor;; Interferon-alpha/beta receptor, fibronectin type III"	Interleukin-10 receptor subunit alpha (Precursor) GN=IL10RA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-10 receptor subunit alpha [Ceratotherium simum simum]
ENSG00000110328(GALNT18)	--	13.57363321	609	11.311768	524	14.07023317	609	19.52169967	855	17.19244898	760	18.671025	846	0.519681726	0.457671377	normal	0.330813542	0.513768363	normal	0.492500184	0.464940177	normal	0.005086052	0.477388751	normal	--	--	--	"K00710|0|pps:100991628|GALNT18, GALNTL4; polypeptide N-acetylgalactosaminyltransferase 18; K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; N-terminal domain of galactosyltransferase	Polypeptide N-acetylgalactosaminyltransferase 18 GN=GALNT18 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 18 [Tupaia chinensis]
ENSG00000110330(BIRC2)	--	13.75543441	712	16.49735173	780	15.27132207	750	17.20590904	880	14.4356321	819	16.84018452	929	0.917991241	0.274260883	normal	0.975447993	0.0488703	normal	0.897842278	0.299952146	normal	0.307399659	0.208107242	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K16060|0|pps:100970636|BIRC2; baculoviral IAP repeat containing 2; K16060 baculoviral IAP repeat-containing protein 2/3 (A)	NF-kappa B signaling pathway (ko04064);; Ubiquitin mediated proteolysis (ko04120);; Apoptosis (ko04210);; Focal adhesion (ko04510);; NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	"Inhibitor of Apoptosis domain;; Caspase recruitment domain;; Zinc finger, C3HC4 type (RING finger)"	Baculoviral IAP repeat-containing protein 2 GN=BIRC2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: baculoviral IAP repeat-containing protein 2 [Galeopterus variegatus] 
ENSG00000110344(UBE4A)	--	59.26411752	2339	75.02908299	2621	66.32822229	2518	76.441075	2640	58.23198915	2401	72.798581	2626	0.983059442	0.143724905	normal	0.982526706	-0.147819359	normal	0.988430365	0.052266451	normal	0.964587023	0.014766757	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Cellular Component: ubiquitin ligase complex (GO:0000151);; Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: ubiquitin-ubiquitin ligase activity (GO:0034450);; 	K10596|0|mcf:102135339|UBE4A; ubiquitination factor E4A; K10596 ubiquitin conjugation factor E4 A [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin elongating factor core;; U-box domain	Ubiquitin conjugation factor E4 A {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	hypothetical protein PANDA_017770 [Ailuropoda melanoleuca]
ENSG00000110367(DDX6)	--	24.94291319	2375	29.37487681	2788	25.84362	2427	28.010316	2740	24.80630802	2350	28.62591701	2678	0.979691829	0.175310466	normal	0.955532326	-0.267837895	normal	0.984267397	0.133611125	normal	0.971576238	0.011973031	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	K12614|0|umr:103662325|DDX6; DEAD (Asp-Glu-Ala-Asp) box helicase 6; K12614 ATP-dependent RNA helicase DDX6/DHH1 [EC:3.6.4.13] (A)	RNA degradation (ko03018)	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX6 GN=DDX6 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX6 [Elephantulus edwardii]
ENSG00000110375(UPK2)	--	1.48193	18	2.24739	28	1.34536	16	0.324764	4	0.64237	7	0.325697	4	--	--	--	0.203260782	-1.812672103	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Uroplakin II	Uroplakin-2 (Precursor) GN=UPK2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: uroplakin-2 [Equus caballus] 
ENSG00000110395(CBL)	--	7.50654676	1383	7.683698935	1419	8.4501659	1533	6.115652149	1123	6.17177151	1126	5.157658665	948	0.873727131	-0.330866697	normal	0.842506937	-0.354668938	normal	0.005620567	-0.700802376	normal	0.00241335	-0.460799133	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: nucleus (GO:0005634);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Molecular Function: metal ion binding (GO:0046872);; 	K04707|0|ggo:101140325|CBL; E3 ubiquitin-protein ligase CBL; K04707 E3 ubiquitin-protein ligase CBL [EC:6.3.2.19] (A)	ErbB signaling pathway (ko04012);; Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; Jak-STAT signaling pathway (ko04630);; T cell receptor signaling pathway (ko04660);; Insulin signaling pathway (ko04910);; Bacterial invasion of epithelial cells (ko05100);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Chronic myeloid leukemia (ko05220)	[V]	Defense mechanisms	"CBL proto-oncogene N-terminal domain 1;; CBL proto-oncogene N-terminus, SH2-like domain;; CBL proto-oncogene N-terminus, EF hand-like domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; UBA/TS-N domain"	E3 ubiquitin-protein ligase CBL GN=CBL OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: E3 ubiquitin-protein ligase CBL [Galeopterus variegatus]
ENSG00000110400(NECTIN1)	--	5.160778539	569	4.666775988	580	6.048215225	627	4.381091907	430	5.02962356	526	3.171215153	358	0.634511533	-0.433572475	normal	0.958250521	-0.161972961	normal	0.00114547	-0.814163896	normal	0.016716494	-0.456048389	normal	--	--	--	"K06081|0|hsa:5818|PVRL1, CD111, CLPED1, ED4, HIgR, HV1S, HVEC, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1; poliovirus receptor-related 1 (herpesvirus entry mediator C); K06081 poliovirus receptor-related protein 1 (A)"	Cell adhesion molecules (CAMs) (ko04514);; Adherens junction (ko04520);; Herpes simplex infection (ko05168)	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Alphaherpesvirus glycoprotein E	Nectin-1 (Precursor) GN=PVRL1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: poliovirus receptor-related protein 1 isoform X1 [Tupaia chinensis]
ENSG00000110422(HIPK3)	--	11.56235501	1341	14.81960249	1572	10.586097	1210	10.74870138	1243	11.33033296	1323	12.50477204	1398	0.974702775	-0.14014836	normal	0.937745758	-0.269931246	normal	0.963506391	0.199833329	normal	0.753082135	-0.077918958	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K08826|0|ptr:451109|HIPK3; homeodomain interacting protein kinase 3; K08826 homeodomain interacting protein kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Homeodomain-interacting protein kinase 3 GN=HIPK3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: homeodomain-interacting protein kinase 3 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000110427(KIAA1549L)	--	2.068054097	409	1.560696886	320	2.214234291	401	3.455145369	709	2.989694137	608	2.11262832	417	0.003252703	0.760657064	normal	0.000190477	0.901431839	normal	0.968954265	0.04797627	normal	0.099793445	0.595313925	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF3827)	UPF0606 protein KIAA1549L GN=KIAA1549L OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: UPF0606 protein KIAA1549L homolog [Panthera tigris altaica]
ENSG00000110429(FBXO3)	--	14.1645094	613	13.31666878	552	12.40616232	629	13.41048454	632	11.56004426	591	11.18683713	548	0.973988195	0.013172706	normal	0.969831299	0.076859784	normal	0.947707585	-0.206642834	normal	0.903323627	-0.04007367	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: protein binding (GO:0005515);; 	K10290|0|pps:100968795|FBXO3; F-box protein 3; K10290 F-box protein 3 (A)	--	[P]	Inorganic ion transport and metabolism	Protein of unknown function (DUF525);; F-box-like;; SMI1 / KNR4 family (SUKH-1);; F-box domain	F-box only protein 3 GN=FBXO3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: F-box only protein 3 isoform 1 [Trichechus manatus latirostris]
ENSG00000110435(PDHX)	--	20.84339644	810	18.13555448	731	16.66263556	711	17.43312039	725	20.94984905	729	16.53596708	645	0.956433337	-0.190391186	normal	0.975071552	-0.025326683	normal	0.964120984	-0.148510049	normal	0.617004805	-0.123127092	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13997|0|ggo:101137782|PDHX; pyruvate dehydrogenase protein X component, mitochondrial isoform 1; K13997 dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex (A)"	--	[C]	Energy production and conversion	2-oxoacid dehydrogenases acyltransferase (catalytic domain);; Biotin-requiring enzyme;; e3 binding domain	"Pyruvate dehydrogenase protein X component, mitochondrial (Precursor) GN=PDHX OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: pyruvate dehydrogenase protein X component, mitochondrial [Galeopterus variegatus]"
ENSG00000110436(SLC1A2)	--	0.033633979	4	0.005629897	1	0.128448045	3	0.044995119	8	0.131010177	11	0.177101103	3	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Molecular Function: symporter activity (GO:0015293);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05613|0|ptr:450180|SLC1A2; solute carrier family 1 (glial high affinity glutamate transporter), member 2; K05613 solute carrier family 1 (glial high affinity glutamate transporter), member 2 (A)"	Glutamatergic synapse (ko04724);; Amyotrophic lateral sclerosis (ALS) (ko05014)	[E]	Amino acid transport and metabolism	Sodium:dicarboxylate symporter family	Excitatory amino acid transporter 2 GN=SLC1A2 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: excitatory amino acid transporter 2 isoform X2 [Oryctolagus cuniculus]
ENSG00000110442(COMMD9)	--	13.78147807	482	16.91559295	474	15.54835093	489	16.15900565	524	20.72689996	645	19.08721312	586	0.968060527	0.089427966	normal	0.673588536	0.421827739	normal	0.926766693	0.252061758	normal	0.234630632	0.259661673	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 9 GN=COMMD9 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: COMM domain-containing protein 9 [Ceratotherium simum simum]
ENSG00000110446(SLC15A3)	--	0	0	0	0	0	0	0.112602	2	0.199685	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14638|0|hsa:51296|SLC15A3, OCTP, PHT2, PTR3; solute carrier family 15 (oligopeptide transporter), member 3; K14638 solute carrier family 15 (peptide/histidine transporter), member 3/4 (A)"	--	[E]	Amino acid transport and metabolism	POT family;; Major Facilitator Superfamily	Solute carrier family 15 member 3 GN=SLC15A3 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 15 member 3 [Oryctolagus cuniculus]
ENSG00000110455(ACCS)	--	11.935307	579	12.3353297	573	10.367236	531	6.585494134	364	6.282131626	378	7.861672722	496	0.017431053	-0.698098002	normal	0.087983974	-0.619546817	normal	0.966740499	-0.106349724	normal	0.016519595	-0.463435362	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	--	--	[T]	Signal transduction mechanisms	Aminotransferase class I and II	1-aminocyclopropane-1-carboxylate synthase-like protein 1 GN=ACCS OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: 1-aminocyclopropane-1-carboxylate synthase-like protein 1 isoform X1 [Equus przewalskii] 
ENSG00000110492(MDK)	--	2.12864799	33	0.495579037	10	0.096057662	1	23.55973109	349	35.69369925	516	16.77162621	248	0	3.313292926	up	0	5.470359099	up	0	6.628196241	up	2.04E-09	4.636910924	up	--	--	--	--	--	--	--	"PTN/MK heparin-binding protein family, C-terminal domain"	--	R	General function prediction only	PREDICTED: midkine isoform X2 [Bison bison bison] 
ENSG00000110497(AMBRA1)	--	9.167399181	959	11.85687197	1257	9.267485189	1000	9.647619726	1012	10.31708522	1098	12.01936816	1268	0.978551033	0.046701469	normal	0.956471077	-0.216254524	normal	0.866301417	0.333813993	normal	0.891389285	0.050154693	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K17985|0|ptr:451154|AMBRA1; autophagy/beclin-1 regulator 1; K17985 activating molecule in BECN1-regulated autophagy protein 1 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Activating molecule in BECN1-regulated autophagy protein 1 GN=AMBRA1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: activating molecule in BECN1-regulated autophagy protein 1 isoform X2 [Equus caballus] 
ENSG00000110514(MADD)	--	12.8366848	1447	13.45759162	1528	12.5700906	1449	12.03461924	1292	10.25729498	1242	15.73304426	1565	0.965815335	-0.194072878	normal	0.894840661	-0.32005387	normal	0.980598808	0.102710451	normal	0.53405498	-0.130779742	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; uDENN domain;; dDENN domain	MAP kinase-activating death domain protein OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: MAP kinase-activating death domain protein isoform 1 [Ceratotherium simum simum]
ENSG00000110536(PTPMT1)	--	45.1539	610	38.08188	571	37.8403	540	50.85583	706	52.61294	713	48.47992	686	0.956938524	0.179605916	normal	0.89575396	0.298276579	normal	0.850126392	0.336120678	normal	0.183951724	0.269170266	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K14165|7.73842e-147|ptr:100610884|PTPMT1; protein tyrosine phosphatase, mitochondrial 1; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain"	Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 (Precursor) GN=PTPMT1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [Ceratotherium simum simum]
ENSG00000110583(NAA40)	--	11.47064615	839	13.57986936	977	11.88131532	856	13.29861533	941	12.40644177	902	11.80022489	858	0.970019294	0.134459068	normal	0.970157083	-0.136437815	normal	0.977821581	-0.004915916	normal	0.989067348	-0.006028262	normal	[KR]	Transcription;; General function prediction only	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	--	--	[R]	General function prediction only	Acetyltransferase (GNAT) family	N-alpha-acetyltransferase 40 GN=NAA40 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: N-alpha-acetyltransferase 40 [Oryctolagus cuniculus]
ENSG00000110619(CARS)	--	29.17769327	1751	28.37589155	1726	26.62625725	1604	18.622002	1112	24.08976214	1431	32.64364064	1966	0.007716047	-0.685093131	normal	0.92612634	-0.291554328	normal	0.933717422	0.285054588	normal	0.641539133	-0.191929161	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K01883|0|hsa:833|CARS, CARS1, CYSRS, MGC:11246; cysteinyl-tRNA synthetase (EC:6.1.1.16); K01883 cysteinyl-tRNA synthetase [EC:6.1.1.16] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class I (C) catalytic domain;; tRNA synthetases class I (M)	"Cysteine--tRNA ligase, cytoplasmic GN=CARS OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: cysteine--tRNA ligase, cytoplasmic [Galeopterus variegatus]"
ENSG00000110628(SLC22A18)	--	27.49913085	585	23.72182619	486	24.04349945	503	22.06276562	441	25.49079003	519	21.60670453	455	0.620311214	-0.437162813	normal	0.968662528	0.073131439	normal	0.959277756	-0.152500996	normal	0.490832923	-0.174723704	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08214|0|hsa:5002|SLC22A18, BWR1A, BWSCR1A, HET, IMPT1, ITM, ORCTL2, SLC22A1L, TSSC5, p45-BWR1A; solute carrier family 22, member 18; K08214 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 18 (A)"	--	--	--	Major Facilitator Superfamily;; Transmembrane secretion effector	Solute carrier family 22 member 18 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 22 member 18 [Vicugna pacos]
ENSG00000110651(CD81)	--	249.0924795	5367	239.5522565	5234	248.5773524	5491	280.4168902	6107	286.5537262	6160	257.2409789	5563	0.990262833	0.15547395	normal	0.984635469	0.213532947	normal	0.993900502	0.010499879	normal	0.564593873	0.126594772	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06508|3.0932e-130|nle:100601600|CD81; CD81 molecule; K06508 CD81 antigen (A)	B cell receptor signaling pathway (ko04662);; Malaria (ko05144);; Hepatitis C (ko05160)	[R]	General function prediction only	Tetraspanin family	CD81 antigen GN=CD81 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CD81 antigen [Tupaia chinensis]
ENSG00000110660(SLC35F2)	--	15.48545	743	17.77241888	669	15.71441033	729	23.58550829	1099	23.428824	1023	16.44307791	730	0.216323498	0.533013596	normal	0.09586758	0.590215028	normal	0.975947749	-0.006300731	normal	0.144530893	0.39145442	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15287|0|hsa:54733|SLC35F2, HSNOV1; solute carrier family 35, member F2; K15287 solute carrier family 35, member F1/2 (A)"	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF914);; EamA-like transporter family;; UAA transporter family;; Triose-phosphate Transporter family	Solute carrier family 35 member F2 GN=SLC35F2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: solute carrier family 35 member F2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000110675(ELMOD1)	--	0.258171311	11	0.217120547	10	0.260566973	9	0.127023612	4	0.081643441	3	0.02087992	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	ELMO/CED-12 family	ELMO domain-containing protein 1 GN=ELMOD1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: ELMO domain-containing protein 1 [Tupaia chinensis]
ENSG00000110693(SOX6)	--	0.059299315	9	0.013167786	2	0.032431596	1	0.070667556	7	0.234605895	26	0.276847525	12	--	--	--	0.004548204	2.953374627	up	--	--	--	--	--	--	--	--	--	K09269|0|pps:100975998|SOX6; SRY (sex determining region Y)-box 6; K09269 transcription factor SOX5/6/13 (SOX group D) (A)	--	[K]	Transcription	HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-6 GN=SOX6 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor SOX-6 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000110696(C11orf58)	--	86.30012321	2635	100.5606186	3060	99.25510829	2980	102.1095448	3151	99.7350405	2972	90.751089	2673	0.971797083	0.22705334	normal	0.989162028	-0.063492253	normal	0.982345812	-0.165055446	normal	1	-0.001637603	normal	--	--	--	--	--	--	--	Small acidic protein family	Small acidic protein GN=SMAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: small acidic protein [Galeopterus variegatus]
ENSG00000110697(PITPNM1)	--	16.20166982	1389	13.32320224	1160	14.27897134	1262	21.10237989	1812	24.36276003	2086	14.80991188	1281	0.852264166	0.352362003	normal	0.000205234	0.824375424	normal	0.982260091	0.013251362	normal	0.20869073	0.420555087	normal	[R]	General function prediction only	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Phosphatidylinositol transfer protein;; DDHD domain;; LNS2 (Lipin/Ned1/Smp2)	Membrane-associated phosphatidylinositol transfer protein 1 GN=PITPNM1 OS=Homo sapiens (Human) PE=1 SV=4	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: membrane-associated phosphatidylinositol transfer protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000110700(RPS13)	--	794.21635	5101	782.21018	5165	740.70815	4906	844.77074	5620	786.520945	5045	777.536	5079	0.992048004	0.108926502	normal	0.992887488	-0.055324247	normal	0.993159245	0.041693166	normal	0.909967383	0.031779396	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02953|6.47953e-105|ecb:100056386|RPS13; ribosomal protein S13; K02953 small subunit ribosomal protein S13e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal S13/S15 N-terminal domain;; Ribosomal protein S15	40S ribosomal protein S13 GN=RPS13 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S13 [Equus caballus] 
ENSG00000110711(AIP)	--	33.636699	846	29.587187	770	31.53462	811	21.88245	560	23.039978	588	26.048372	666	0.047851136	-0.624657854	normal	0.701072637	-0.409545324	normal	0.902756688	-0.29186957	normal	0.010703716	-0.440642893	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17767|0|ggo:101137516|AIP; AH receptor-interacting protein; K17767 AH receptor-interacting protein (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; TPR repeat	AH receptor-interacting protein GN=AIP OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: AH receptor-interacting protein [Galeopterus variegatus]
ENSG00000110713(NUP98)	--	33.53853955	3495	32.63967954	3300	32.97347171	3279	36.067862	3751	38.77657756	3809	33.66635193	3519	0.990620903	0.071120362	normal	0.982546277	0.185440553	normal	0.989366737	0.093576503	normal	0.590622666	0.115786986	normal	--	--	Cellular Component: nuclear pore (GO:0005643);; Biological Process: transport (GO:0006810);; 	K14297|0|ggo:101154013|NUP98; nuclear pore complex protein Nup98-Nup96 isoform 1; K14297 nuclear pore complex protein Nup98-Nup96 (A)	RNA transport (ko03013);; Influenza A (ko05164)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Nuclear protein 96;; Nucleoporin autopeptidase;; Nucleoporin FG repeat region	Nuclear pore complex protein Nup96 (Precursor) GN=NUP98 OS=Homo sapiens (Human) PE=1 SV=4	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup98-Nup96 [Lipotes vexillifer]
ENSG00000110717(NDUFS8)	--	152.5282788	1451	141.3743338	1383	149.7208881	1498	159.276907	1572	174.6310377	1614	142.0872126	1359	0.981796007	0.084635324	normal	0.965651789	0.201209038	normal	0.975088519	-0.148626011	normal	0.857453702	0.047791903	normal	[C]	Energy production and conversion	--	"K03941|9.89114e-125|ptr:451375|NDUFS8; NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3); K03941 NADH dehydrogenase (ubiquinone) Fe-S protein 8 [EC:1.6.5.3 1.6.99.3] (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	4Fe-4S binding domain;; 4Fe-4S dicluster domain;; 4Fe-4S double cluster binding domain;; 4Fe-4S dicluster domain;; 4Fe-4S dicluster domain;; 4Fe-4S dicluster domain;; 4Fe-4S dicluster domain;; 4Fe-4S binding domain;; 4Fe-4S binding domain;; 4Fe-4S binding domain;; 4Fe-4S dicluster domain;; 4Fe-4S dicluster domain	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (Precursor) GN=NDUFS8 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial [Ochotona princeps]"
ENSG00000110719(TCIRG1)	--	49.11179199	2387	41.55003781	2063	42.19158813	2116	53.63274742	2624	57.70379921	2800	51.94571392	2514	0.986040608	0.105672004	normal	0.733507063	0.418991887	normal	0.963295765	0.240195906	normal	0.138478241	0.252434612	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V0 domain (GO:0033179);; "	"K02154|0|hsa:10312|TCIRG1, ATP6N1C, ATP6V0A3, Atp6i, OC-116kDa, OC116, OPTB1, Stv1, TIRC7, Vph1, a3; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 (EC:3.6.3.6); K02154 V-type H+-transporting ATPase subunit a (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Tuberculosis (ko05152);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	V-type ATPase 116kDa subunit family	V-type proton ATPase 116 kDa subunit a isoform 3 GN=TCIRG1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: V-type proton ATPase 116 kDa subunit a isoform 3 [Galeopterus variegatus]
ENSG00000110721(CHKA)	--	15.42354504	641	23.358152	945	16.597461	711	16.01514711	691	16.58035037	709	16.206338	691	0.972182747	0.077350504	normal	0.616356739	-0.435148273	normal	0.974483146	-0.049348814	normal	0.635174568	-0.157004478	normal	--	--	--	"K14156|0|hsa:1119|CHKA, CHK, CK, CKI, EK; choline kinase alpha (EC:2.7.1.32 2.7.1.82); K14156 choline/ethanolamine kinase [EC:2.7.1.32 2.7.1.82] (A)"	Glycerophospholipid metabolism (ko00564);; Choline metabolism in cancer (ko05231)	[M]	Cell wall/membrane/envelope biogenesis	Choline/ethanolamine kinase;; Phosphotransferase enzyme family;; Ecdysteroid kinase	Choline kinase alpha GN=CHKA OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: choline kinase alpha isoform 1 [Orcinus orca]
ENSG00000110723(EXPH5)	--	0.086994395	17	0.292268736	16	0.037939046	6	0.425740375	81	0.219354489	41	0.182547381	36	1.66E-06	2.125397645	up	0.403777347	1.25939214	normal	0.003764934	2.31274938	up	0.019902892	1.992986574	normal	--	--	--	--	--	--	--	--	Exophilin-5 GN=EXPH5 OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exophilin-5 [Galeopterus variegatus]
ENSG00000110756(HPS5)	--	10.90167804	891	10.60995741	860	10.0032213	824	9.459580307	784	9.004833016	719	9.151381	729	0.950081292	-0.215008435	normal	0.915199332	-0.279233605	normal	0.958332705	-0.184656414	normal	0.250809028	-0.227770753	normal	--	--	--	--	--	--	--	--	Hermansky-Pudlak syndrome 5 protein GN=HPS5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: Hermansky-Pudlak syndrome 5 protein isoform X1 [Physeter catodon] 
ENSG00000110768(GTF2H1)	--	20.54163153	987	25.72361294	1220	24.64114312	1113	22.598309	1119	19.98093375	957	29.4978525	1401	0.970166253	0.150036341	normal	0.804046016	-0.371195936	normal	0.88430263	0.323319541	normal	0.914498188	0.046059635	normal	--	--	--	"K03141|0|hsa:2965|GTF2H1, BTF2, P62, TFB1, TFIIH; general transcription factor IIH, polypeptide 1, 62kDa; K03141 transcription initiation factor TFIIH subunit 1 (A)"	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420);; Viral carcinogenesis (ko05203)	[KL]	"Transcription;; Replication, recombination and repair"	"BSD domain;; TFIIH p62 subunit, N-terminal domain"	General transcription factor IIH subunit 1 GN=GTF2H1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor IIH subunit 1 [Panthera tigris altaica]
ENSG00000110786(PTPN5)	--	0.035188273	2	0	0	0.0213491	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18018|0|ptr:466462|PTPN5; protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched); K18018 tyrosine-protein phosphatase non-receptor type 5 [EC:3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase	Tyrosine-protein phosphatase non-receptor type 5 GN=PTPN5 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 5 isoform 1 [Ceratotherium simum simum]
ENSG00000110799(VWF)	--	0.0103607	2	0	0	0.0100231	1	0	0	0	0	0.0103339	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03900|0|hsa:7450|VWF, F8VWF, VWD; von Willebrand factor; K03900 von Willebrand factor (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Complement and coagulation cascades (ko04610);; Platelet activation (ko04611)	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type D domain;; von Willebrand factor type A domain;; C8 domain;; Trypsin Inhibitor like cysteine rich domain;; von Willebrand factor type C domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	von Willebrand antigen 2 (Precursor) GN=VWF OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: von Willebrand factor [Panthera tigris altaica]
ENSG00000110801(PSMD9)	--	36.76252027	730	44.99005707	806	50.91792039	860	50.84841633	1004	46.6798975	920	50.56854695	924	0.625786754	0.428187377	normal	0.963185086	0.169130276	normal	0.974545584	0.09510338	normal	0.238320253	0.228042275	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K06693|7.7891e-163|ggo:101152227|PSMD9; 26S proteasome non-ATPase regulatory subunit 9 isoform 1; K06693 26S proteasome non-ATPase regulatory subunit 9 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	PDZ domain;; PDZ domain (Also known as DHR or GLGF)	26S proteasome non-ATPase regulatory subunit 9 GN=PSMD9 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 9 [Ailuropoda melanoleuca]
ENSG00000110811(P3H3)	--	20.0453582	1023	16.996082	876	18.2900187	985	19.56667484	1042	23.13421556	1191	13.72548072	726	0.979911644	-0.004276767	normal	0.667539663	0.421118389	normal	0.553900104	-0.447641874	normal	0.980087625	0.015127898	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[S]	Function unknown	2OG-Fe(II) oxygenase superfamily	Prolyl 3-hydroxylase 3 (Precursor) GN=LEPREL2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: prolyl 3-hydroxylase 3 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000110841(PPFIBP1)	--	24.48921668	2165	23.9977222	1863	24.35425745	2047	16.20645136	1371	17.20481313	1462	14.832248	1265	0.006531151	-0.689350109	normal	0.826915519	-0.370770244	normal	0.004839443	-0.701998903	normal	3.38E-05	-0.589273177	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Liprin-beta-1 GN=PPFIBP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: liprin-beta-1 isoform 1 [Ceratotherium simum simum]
ENSG00000110844(PRPF40B)	--	3.709480644	286	3.107171458	193	3.596288402	275	2.966319927	215	3.008906	231	3.1207245	206	0.720596331	-0.439775413	normal	0.936880106	0.236172076	normal	0.764108984	-0.42238538	normal	0.481167566	-0.230626239	normal	[A]	RNA processing and modification	Molecular Function: protein binding (GO:0005515);; 	K12821|0|pps:100973816|PRPF40B; PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae); K12821 pre-mRNA-processing factor 40 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	FF domain;; WW domain	Pre-mRNA-processing factor 40 homolog B GN=PRPF40B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pre-mRNA-processing factor 40 homolog B [Vicugna pacos]
ENSG00000110851(PRDM4)	--	10.865015	865	10.762167	852	9.136837622	752	12.265603	1037	14.4164608	1053	13.94501557	1153	0.946469156	0.23043738	normal	0.916321715	0.283699865	normal	0.056944387	0.607302893	normal	0.025546511	0.37229788	normal	[R]	General function prediction only	--	"K12463|0|hsa:11108|PRDM4, PFM1; PR domain containing 4; K12463 PR domain zinc finger protein 4 (A)"	Neurotrophin signaling pathway (ko04722)	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	PR domain zinc finger protein 4 GN=PRDM4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: PR domain zinc finger protein 4 [Vicugna pacos]
ENSG00000110852(CLEC2B)	--	2.043194	47	3.246480275	78	1.58457048	37	2.373451044	58	1.850770141	44	4.018301	95	0.969803613	0.26475804	normal	0.496274803	-0.825788543	normal	0.003127499	1.317330109	up	0.791269698	0.261526551	normal	--	--	--	"K10071|5.76368e-92|ptr:473359|CLEC2B; C-type lectin domain family 2, member B; K10071 C-type lectin domain family 2 member B (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; UL45 protein	C-type lectin domain family 2 member B GN=CLEC2B OS=Homo sapiens (Human) PE=2 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 2 member B [Equus przewalskii]
ENSG00000110871(COQ5)	--	22.548321	591	21.58686826	564	22.2369139	559	17.11336674	455	18.84483301	485	18.42254	488	0.709155264	-0.406914242	normal	0.933138029	-0.238446736	normal	0.947329662	-0.203668375	normal	0.183230081	-0.284377797	normal	[H]	Coenzyme transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K06127|0|hsa:84274|COQ5; coenzyme Q5 homolog, methyltransferase (S. cerevisiae) (EC:2.1.1.201); K06127 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.201] (A)"	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130)	[H]	Coenzyme transport and metabolism	ubiE/COQ5 methyltransferase family;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Hypothetical methyltransferase	"2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial (Precursor) GN=COQ5 OS=Homo sapiens (Human) PE=1 SV=2"	H	Coenzyme transport and metabolism	"PREDICTED: 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial [Myotis brandtii]"
ENSG00000110876(SELPLG)	--	0.231269893	10	0.062419648	3	0.242970881	8	0.316048072	15	0.546290557	25	0.257917031	12	--	--	--	0.029251932	2.537508905	normal	--	--	--	--	--	--	--	--	--	"K06544|7.79526e-99|hsa:6404|SELPLG, CD162, CLA, PSGL-1, PSGL1; selectin P ligand; K06544 selectin P ligand (A)"	Cell adhesion molecules (CAMs) (ko04514);; Staphylococcus aureus infection (ko05150)	--	--	--	P-selectin glycoprotein ligand 1 (Precursor) GN=SELPLG OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: P-selectin glycoprotein ligand 1 [Galeopterus variegatus]
ENSG00000110880(CORO1C)	--	48.87185982	3579	50.08764572	3562	55.01403983	3931	105.9620922	7441	71.21602949	5186	76.64007764	5091	7.41E-08	1.024796156	up	0.366508284	0.520324061	normal	0.89772333	0.364637666	normal	0.021918729	0.655983731	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K13886|0|hsa:23603|CORO1C, HCRNN4; coronin, actin binding protein, 1C; K13886 coronin-1B/1C/6 (A)"	--	[Z]	Cytoskeleton	"Domain of unknown function (DUF1900);; Domain of unknown function (DUF1899);; WD domain, G-beta repeat"	Coronin-1C GN=CORO1C OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: coronin-1C [Myotis lucifugus]
ENSG00000110881(ASIC1)	--	5.80815718	426	4.578782194	335	4.485811704	342	3.73252204	276	5.782766262	385	3.882129958	270	0.0672376	-0.654061632	normal	0.950725652	0.178518597	normal	0.853495241	-0.347594314	normal	0.408938591	-0.26577919	normal	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	K04829|0|mcf:102146411|ASIC1; acid-sensing (proton-gated) ion channel 1; K04829 acid-sensing ion channel 1 (A)	Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Acid-sensing ion channel 1 GN=ASIC1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: acid-sensing ion channel 1 [Eptesicus fuscus]
ENSG00000110888(CAPRIN2)	--	8.023819231	741	6.401592698	568	8.01523089	728	9.689969206	868	10.18046974	850	9.22094176	826	0.955272448	0.197011523	normal	0.175376223	0.558921294	normal	0.961033337	0.173573184	normal	0.109006295	0.299565758	normal	--	--	--	"K18744|0|ptr:465366|CAPRIN2, C1QDC1; caprin family member 2; K18744 caprin-2 (A)"	--	--	--	C1q domain;; Cytoplasmic activation/proliferation-associated protein-1 C term	Caprin-2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: caprin-2 [Tursiops truncatus]
ENSG00000110900(TSPAN11)	--	0.072266932	8	0.04302243	5	0.115184395	13	0.070406726	8	0.059058837	5	0.077880984	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17352|0|hsa:441631|TSPAN11, VSSW1971; tetraspanin 11; K17352 tetraspanin-11 (A)"	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-11 GN=TSPAN11 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: tetraspanin-11 isoform X2 [Ailuropoda melanoleuca]
ENSG00000110906(KCTD10)	--	25.80436574	1122	17.69237712	1049	22.69264631	1158	27.03726717	1389	29.67990499	1324	23.89710877	1285	0.927945291	0.276800477	normal	0.895483046	0.314058094	normal	0.973743424	0.141665966	normal	0.173141434	0.242892444	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: protein homooligomerization (GO:0051260);; 	"K15074|0|hsa:83892|KCTD10, BTBD28, ULRO61, hBACURD3; potassium channel tetramerization domain containing 10; K15074 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein (A)"	--	[P]	Inorganic ion transport and metabolism	BTB/POZ domain;; BTB/POZ domain	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 GN=KCTD10 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 [Bos taurus] 
ENSG00000110911(SLC11A2)	--	26.2234867	1494	25.66001489	1449	26.31082252	1387	27.19598673	1480	26.61278468	1503	30.888725	1702	0.983344545	-0.04436939	normal	0.983183592	0.031328752	normal	0.927670908	0.286689163	normal	0.687987147	0.092805487	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K12347|0|hsa:4891|SLC11A2, DCT1, DMT1, NRAMP2; solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2; K12347 natural resistance-associated macrophage protein (A)"	Lysosome (ko04142);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Natural resistance-associated macrophage protein	Natural resistance-associated macrophage protein 2 GN=SLC11A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: natural resistance-associated macrophage protein 2 isoform X1 [Vicugna pacos]
ENSG00000110917(MLEC)	--	63.201514	6834	55.616682	6484	59.78214703	6478	76.720649	8443	81.57473302	8775	78.00102	8586	0.977573712	0.274137671	normal	0.858745727	0.415004988	normal	0.881399271	0.398065288	normal	0.032457587	0.361229121	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Di-glucose binding within endoplasmic reticulum	Malectin (Precursor) GN=MLEC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: malectin [Sorex araneus]
ENSG00000110921(MVK)	--	17.90814941	631	18.55328802	682	18.81550709	643	8.367971798	307	10.15933279	371	20.80494764	650	1.12E-06	-1.066425661	down	0.000142351	-0.897038618	normal	0.974566088	0.007312433	normal	0.141813224	-0.577644303	normal	[I]	Lipid transport and metabolism	Molecular Function: ATP binding (GO:0005524);; 	"K00869|0|hsa:4598|MVK, LRBP, MK, MVLK, POROK3; mevalonate kinase (EC:2.7.1.36); K00869 mevalonate kinase [EC:2.7.1.36] (A)"	Terpenoid backbone biosynthesis (ko00900);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	GHMP kinases N terminal domain;; GHMP kinases C terminal	Mevalonate kinase GN=MVK OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: mevalonate kinase [Galeopterus variegatus]
ENSG00000110925(CSRNP2)	--	6.015014663	494	6.982909505	503	5.766655065	442	5.86098	465	7.369898368	539	6.265310119	474	0.96455989	-0.11773507	normal	0.968698417	0.078073537	normal	0.967012181	0.092244425	normal	0.968639418	0.01730641	normal	--	--	--	"K17494|0|hsa:81566|CSRNP2, C12orf2, C12orf22, FAM130A1, PPP1R72, TAIP-12; cysteine-serine-rich nuclear protein 2; K17494 cysteine/serine-rich nuclear protein (A)"	--	[R]	General function prediction only	--	Cysteine/serine-rich nuclear protein 2 GN=CSRNP2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cysteine/serine-rich nuclear protein 2 [Loxodonta africana]
ENSG00000110931(CAMKK2)	--	13.91377641	1253	11.27830261	1015	13.401654	1207	12.96866744	1149	13.14997461	1168	10.36007806	927	0.971324244	-0.155640492	normal	0.964618173	0.180882598	normal	0.754332554	-0.388518736	normal	0.60808479	-0.120835393	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07359|0|hsa:10645|CAMKK2, CAMKK, CAMKKB; calcium/calmodulin-dependent protein kinase kinase 2, beta (EC:2.7.11.17); K07359 calcium/calmodulin-dependent protein kinase kinase [EC:2.7.11.17] (A)"	AMPK signaling pathway (ko04152);; Adipocytokine signaling pathway (ko04920);; Oxytocin signaling pathway (ko04921);; Alcoholism (ko05034)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Calcium/calmodulin-dependent protein kinase kinase 2 GN=CAMKK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase kinase 2 isoform X1 [Galeopterus variegatus]
ENSG00000110934(BIN2)	--	0	0	0.019939195	1	0	0	0.044608138	2	0.043292807	1	0.058799329	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	BAR domain	Bridging integrator 2 GN=BIN2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: bridging integrator 2 isoform 1 [Ceratotherium simum simum]
ENSG00000110944(IL23A)	--	0.114229	2	0	0	0.054823	0	0.0564846	1	0.111626	1	0.11202	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; 	"K05426|1.03402e-107|ptr:467036|IL23A; interleukin 23, alpha subunit p19; K05426 interleukin 23, alpha subunit p19 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Pertussis (ko05133);; Tuberculosis (ko05152);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323)	--	--	Interleukin-6/G-CSF/MGF family	Interleukin-23 subunit alpha (Precursor) GN=IL23A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	interleukin-23 subunit alpha precursor [Equus caballus] 
ENSG00000110955(ATP5B)	--	432.3296764	12744	385.1047859	11670	428.942716	12807	496.1993175	14809	467.1671385	13667	449.5015399	13273	0.994053383	0.185802994	normal	0.992293281	0.206440736	normal	0.996862829	0.04326546	normal	0.535298568	0.144194306	normal	[C]	Energy production and conversion	Molecular Function: ATP binding (GO:0005524);; Biological Process: proton transport (GO:0015992);; Biological Process: ATP metabolic process (GO:0046034);; 	"K02133|0|hsa:506|ATP5B, ATPMB, ATPSB, HEL-S-271; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14); K02133 F-type H+-transporting ATPase subunit beta [EC:3.6.3.14] (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"ATP synthase alpha/beta family, nucleotide-binding domain;; ATP synthase alpha/beta chain, C terminal domain;; ATP synthase alpha/beta family, beta-barrel domain"	"ATP synthase subunit beta, mitochondrial (Precursor) GN=ATP5B OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	Bromodomain adjacent to zinc finger domain protein 2A [Pteropus alecto]
ENSG00000110958(PTGES3)	--	276.4843196	7738	280.3616252	7936	298.0578077	8270	342.4642435	9755	281.359753	7853	280.6147315	7865	0.971420604	0.303295148	normal	0.995148529	-0.036587678	normal	0.994857981	-0.080716868	normal	0.7980203	0.067475603	normal	--	--	--	K15730|3.28775e-106|cfr:102515833|PTGES3; prostaglandin E synthase 3 (cytosolic); K15730 cytosolic prostaglandin-E synthase [EC:5.3.99.3] (A)	Arachidonic acid metabolism (ko00590)	[O]	"Posttranslational modification, protein turnover, chaperones"	CS domain	Prostaglandin E synthase 3 GN=PTGES3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prostaglandin E synthase 3 [Camelus ferus]
ENSG00000110987(BCL7A)	--	5.048847987	383	6.101264	433	5.085571	415	6.320015	471	8.305897	539	8.03365	603	0.916922264	0.266584698	normal	0.897833242	0.293571141	normal	0.289606793	0.529146588	normal	0.075231795	0.369487866	normal	--	--	--	--	--	[R]	General function prediction only	"BCL7, N-terminal conserver region"	B-cell CLL/lymphoma 7 protein family member A GN=BCL7A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: B-cell CLL/lymphoma 7 protein family member A isoform 1 [Ceratotherium simum simum]
ENSG00000111011(RSRC2)	--	11.86718868	727	14.60674038	816	14.39126412	861	13.0548705	799	15.32707023	987	15.47847528	962	0.971463295	0.105195768	normal	0.935040273	0.252628133	normal	0.96785676	0.151480389	normal	0.418173418	0.172538583	normal	--	--	--	--	--	--	--	Small acidic protein family	Arginine/serine-rich coiled-coil protein 2 GN=RSRC2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: arginine/serine-rich coiled-coil protein 2 [Leptonychotes weddellii]
ENSG00000111052(LIN7A)	--	1.055133719	100	2.111313	105	0.8464776	77	0.564457	54	0.959764	52	0.687976	66	0.173300463	-0.900663055	normal	0.049468533	-1.014049447	normal	0.965141191	-0.225887078	normal	0.079423318	-0.734397755	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	PDZ domain (Also known as DHR or GLGF);; L27 domain	Protein lin-7 homolog A GN=LIN7A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein lin-7 homolog A [Mustela putorius furo]
ENSG00000111057(KRT18)	--	741.98541	24706	628.910735	21423	747.9239642	25692	797.59449	27080	881.44135	29242	735.142663	24679	0.997919095	0.101527992	normal	0.926064237	0.427428986	normal	0.998096216	-0.066322723	normal	0.543659221	0.152364877	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|ptr:451923|KRT18; keratin 18; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 18 GN=KRT18 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: keratin, type I cytoskeletal 18-like [Lipotes vexillifer]"
ENSG00000111058(ACSS3)	--	0.289733	16	0.3720409	21	0.17568112	8	0.4198497	17	1.107250823	78	0.524979725	31	--	--	--	8.84E-05	1.799962075	up	0.165543701	1.765681348	normal	0.346765848	1.46457763	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K01908|0|hsa:79611|ACSS3; acyl-CoA synthetase short-chain family member 3 (EC:6.2.1.1); K01908 propionyl-CoA synthetase [EC:6.2.1.17] (A)	Propanoate metabolism (ko00640)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	"Acyl-CoA synthetase short-chain family member 3, mitochondrial (Precursor) GN=ACSS3 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: acyl-CoA synthetase short-chain family member 3, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000111077(TNS2)	--	5.535217106	572	5.908062613	611	5.412451184	579	4.484740274	464	4.782467206	464	4.397292219	460	0.855984073	-0.331731117	normal	0.688268355	-0.417284839	normal	0.846547381	-0.339224602	normal	0.067200656	-0.365467214	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K18080|0|hsa:23371|TENC1, C1-TEN, C1TEN, TNS2; tensin like C1 domain containing phosphatase (tensin 2); K18080 tensin (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	Phosphotyrosine-binding domain;; C2 domain of PTEN tumour-suppressor protein;; SH2 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Tensin-like C1 domain-containing phosphatase GN=TENC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tensin-like C1 domain-containing phosphatase isoform X2 [Vicugna pacos]
ENSG00000111087(GLI1)	--	6.735375845	524	6.801656747	533	5.877091705	433	2.682518281	162	3.50253833	223	3.0816568	115	1.11E-15	-1.714820786	down	8.11E-09	-1.272752785	down	0	-1.907138059	down	2.64E-13	-1.597454224	down	[R]	General function prediction only	--	K16797|0|ptr:100615503|GLI1; GLI family zinc finger 1; K16797 zinc finger protein GLI1 (A)	cAMP signaling pathway (ko04024);; Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein GLI1 GN=GLI1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	zinc finger protein GLI1 [Sus scrofa] 
ENSG00000111110(PPM1H)	--	8.578811	889	9.617099	1029	10.01193	974	8.315146	840	9.00966541	950	12.49742541	1209	0.972373383	-0.112426419	normal	0.970921214	-0.136461324	normal	0.901901126	0.303105937	normal	0.943965731	0.032317129	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K17503|0|hsa:57460|PPM1H, ARHCL1, NERPP-2C, URCC2; protein phosphatase, Mg2+/Mn2+ dependent, 1H (EC:3.1.3.16); K17503 protein phosphatase 1H [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C	Protein phosphatase 1H GN=PPM1H OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1H [Odobenus rosmarus divergens]
ENSG00000111142(METAP2)	--	49.21966368	2420	46.56480309	2254	52.56436368	2420	51.46635236	2582	55.4599535	2614	42.78906816	2021	0.987907443	0.062611204	normal	0.976140838	0.192225221	normal	0.950653213	-0.268045609	normal	0.993382203	0.003044867	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K01265|0|pps:100988070|METAP2; methionyl aminopeptidase 2; K01265 methionyl aminopeptidase [EC:3.4.11.18] (A)	--	[R]	General function prediction only	Metallopeptidase family M24	Methionine aminopeptidase 2 {ECO:0000255|HAMAP-Rule:MF_03175} OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: methionine aminopeptidase 2 isoformX8 [Canis lupus familiaris] 
ENSG00000111144(LTA4H)	--	83.267962	2904	70.58833103	2445	78.83006429	2708	84.72928443	2977	86.25205746	2981	80.99343027	2818	0.990083583	0.004982901	normal	0.958449847	0.264387049	normal	0.989091127	0.049125536	normal	0.643260708	0.102042518	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	K01254|0|pps:100984721|LTA4H; leukotriene A4 hydrolase; K01254 leukotriene-A4 hydrolase [EC:3.3.2.6] (A)	Arachidonic acid metabolism (ko00590)	[IOVE]	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms;; Amino acid transport and metabolism"	"Peptidase family M1;; Leukotriene A4 hydrolase, C-terminal;; Peptidase MA superfamily"	Leukotriene A-4 hydrolase GN=LTA4H OS=Homo sapiens (Human) PE=1 SV=2	EIOV	"Amino acid transport and metabolism;; Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms"	PREDICTED: leukotriene A-4 hydrolase isoform X1 [Galeopterus variegatus]
ENSG00000111145(ELK3)	--	27.06324163	1857	26.07775373	1791	27.00264216	1927	40.0080675	2791	38.9366388	2677	28.36882878	1988	0.147313164	0.556598084	normal	0.162633421	0.558037434	normal	0.986336014	0.036641431	normal	0.064092953	0.397422182	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09430|0|hsa:2004|ELK3, ERP, NET, SAP2; ELK3, ETS-domain protein (SRF accessory protein 2); K09430 ETS domain-containing protein Elk-3 (SRF accessory protein 2) (A)"	--	[K]	Transcription	Ets-domain	ETS domain-containing protein Elk-3 GN=ELK3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS domain-containing protein Elk-3 isoform 1 [Dasypus novemcinctus] 
ENSG00000111181(SLC6A12)	--	0.235271101	6	0	0	0.0883229	2	0.121025797	5	0.178287846	5	0.082040903	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05039|0|hsa:6539|SLC6A12, BGT-1, BGT1, GAT2; solute carrier family 6 (neurotransmitter transporter), member 12; K05039 solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium- and chloride-dependent betaine transporter GN=SLC6A12 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium- and chloride-dependent betaine transporter [Orycteropus afer afer]
ENSG00000111186(WNT5B)	--	0.799364678	22	0.311033308	12	0.263136716	11	1.223692506	55	1.990763523	80	0.673981869	28	0.173798186	1.234876804	normal	1.67E-08	2.572717077	up	0.78120733	1.230392243	normal	0.036004904	1.833948486	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00444|0|hsa:81029|WNT5B; wingless-type MMTV integration site family, member 5B; K00444 wingless-type MMTV integration site family, member 5 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-5b (Precursor) GN=WNT5B OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-5b [Trichechus manatus latirostris]
ENSG00000111196(MAGOHB)	--	13.74109033	282	15.039129	279	16.86650026	333	20.49257031	378	13.9475656	306	14.93424024	295	0.784773627	0.390017876	normal	0.961054022	0.111263973	normal	0.950506233	-0.182218869	normal	0.752582568	0.109342993	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	K12877|1.3368e-104|umr:103669121|MAGOHB; mago-nashi homolog B (Drosophila); K12877 protein mago nashi (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040)	[A]	RNA processing and modification	Mago nashi protein	Protein mago nashi homolog 2 GN=MAGOHB OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"Protein mago nashi-like protein 2, partial [Bos mutus]"
ENSG00000111199(TRPV4)	--	0.074137712	4	0	0	0	0	0	0	0.083543912	4	0.024044784	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04973|0|pps:100983299|TRPV4; transient receptor potential cation channel, subfamily V, member 4; K04973 transient receptor potential cation channel subfamily V member 4 (A)"	Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ion transport protein;; Ankyrin repeats (many copies)	Transient receptor potential cation channel subfamily V member 4 GN=TRPV4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	transient receptor potential cation channel subfamily V member 4 [Canis lupus familiaris] 
ENSG00000111203(ITFG2)	--	4.1716139	222	6.434051	263	4.530444	239	4.810635	231	5.946604	274	6.173485	290	0.96672705	0.026322325	normal	0.965753655	0.037475416	normal	0.920832706	0.269202225	normal	0.763585599	0.114424453	normal	--	--	--	--	--	--	--	"Ciliary BBSome complex subunit 2, middle region;; FG-GAP repeat"	Integrin-alpha FG-GAP repeat-containing protein 2 GN=ITFG2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: integrin-alpha FG-GAP repeat-containing protein 2 [Galeopterus variegatus]
ENSG00000111206(FOXM1)	--	33.7815409	2490	36.837831	2689	40.73629989	3015	38.73244965	2832	32.831104	2386	41.2865558	3059	0.982739243	0.154753681	normal	0.976547655	-0.193786488	normal	0.990284071	0.012604386	normal	0.985893701	-0.006230518	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09406|0|pps:100967450|FOXM1; forkhead box M1; K09406 forkhead box protein M (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein M1 GN=FOXM1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: forkhead box protein M1 isoform X2 [Mustela putorius furo] 
ENSG00000111215(PRR4)	--	3.461961788	50	2.288256005	32	3.868061539	59	3.871926	57	3.442747	49	5.850056639	87	0.975617768	0.153773966	normal	0.930346841	0.571321843	normal	0.85756746	0.540532616	normal	0.48666809	0.433733469	normal	--	--	--	--	--	--	--	Proline-rich	Proline-rich protein 4 (Precursor) GN=PRR4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	--
ENSG00000111224(PARP11)	--	1.336646136	85	1.5270779	83	1.89735201	104	1.316959265	85	1.64071214	105	2.2079222	111	0.972572114	-0.030284849	normal	0.940278011	0.312704101	normal	0.968431566	0.084495248	normal	0.838630308	0.126198003	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15259|0|mcf:102118062|PARP11; poly (ADP-ribose) polymerase family, member 11; K15259 poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain;; WWE domain	Poly [ADP-ribose] polymerase 11 GN=PARP11 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: poly [ADP-ribose] polymerase 11 isoform X1 [Loxodonta africana]
ENSG00000111229(ARPC3)	--	215.2888848	3423	224.4270126	3211	197.69678	3114	260.8805243	4139	251.8578822	3850	253.2256354	4074	0.972765783	0.243089351	normal	0.972338901	0.240305747	normal	0.858030506	0.379224118	normal	0.086433407	0.286046766	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; Cellular Component: Arp2/3 protein complex (GO:0005885);; Biological Process: regulation of actin filament polymerization (GO:0030833);; Biological Process: Arp2/3 complex-mediated actin nucleation (GO:0034314);; 	"K05756|7.21385e-131|umr:103661171|ARPC3; actin related protein 2/3 complex, subunit 3, 21kDa; K05756 actin related protein 2/3 complex, subunit 3 (A)"	Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	ARP2/3 complex ARPC3 (21 kDa) subunit	Actin-related protein 2/3 complex subunit 3 GN=ARPC3 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	actin-related protein 2/3 complex subunit 3 [Bos taurus] 
ENSG00000111231(GPN3)	--	21.97004431	462	22.92350814	512	25.71486476	549	23.25274536	520	20.18350541	442	21.46949404	465	0.96165802	0.139349536	normal	0.934814297	-0.232783201	normal	0.928923077	-0.247126298	normal	0.686594367	-0.115323472	normal	[R]	General function prediction only	--	"K06883|0|hsa:51184|GPN3, ATPBD1C; GPN-loop GTPase 3; K06883 (A)"	--	[K]	Transcription	Conserved hypothetical ATP binding protein	GPN-loop GTPase 3 {ECO:0000303|Ref.2} GN=ATPBD1C OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: GPN-loop GTPase 3 isoform X2 [Tupaia chinensis]
ENSG00000111237(VPS29)	--	58.58649391	942	53.9330614	882	62.15619108	982	69.65979712	1158	62.48738334	1033	56.66567343	929	0.929777525	0.266611273	normal	0.955493783	0.206236116	normal	0.975984375	-0.088196205	normal	0.552787831	0.131315869	normal	[R]	General function prediction only	--	"K18467|3.12629e-157|hsa:51699|VPS29, DC15, PEP11; vacuolar protein sorting 29 homolog (S. cerevisiae) (EC:3.1.3.3); K18467 vacuolar protein sorting-associated protein 29 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Calcineurin-like phosphoesterase superfamily domain;; Calcineurin-like phosphoesterase	Vacuolar protein sorting-associated protein 29 GN=VPS29 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 29 isoform X3 [Bison bison bison]
ENSG00000111245(MYL2)	--	0	0	0	0	0.0836184	0	0.164921559	2	0.421582428	4	0.0850042	1	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K10351|2.91093e-107|hsa:4633|MYL2, CMH10, MLC2; myosin, light chain 2, regulatory, cardiac, slow; K10351 myosin regulatory light chain 2 (A)"	Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Focal adhesion (ko04510);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair	"Myosin regulatory light chain 2, ventricular/cardiac muscle isoform GN=MYL2 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: myosin regulatory light chain 2, ventricular/cardiac muscle isoform [Oryctolagus cuniculus]"
ENSG00000111247(RAD51AP1)	--	11.86714	384	13.2800668	423	13.26550531	416	14.17850762	473	13.4273404	435	12.71030512	415	0.915451018	0.268930708	normal	0.969376448	0.018864674	normal	0.970055952	-0.011720973	normal	0.773040981	0.091826807	normal	--	--	--	--	--	--	--	--	RAD51-associated protein 1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: RAD51-associated protein 1 [Galeopterus variegatus]
ENSG00000111249(CUX2)	--	0	0	0	0	0.006305647	0	0.019596883	3	0.063221454	9	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09313|0|hsa:23316|CUX2, CDP2, CUTL2; cut-like homeobox 2; K09313 homeobox protein cut-like (A)"	--	[K]	Transcription	CUT domain;; Homeobox domain;; Homeobox KN domain	Homeobox protein cut-like 2 GN=CUX2 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: homeobox protein cut-like 2 [Odobenus rosmarus divergens]
ENSG00000111252(SH2B3)	--	5.560500631	525	4.495841016	421	6.158588631	512	6.344297013	570	6.290218	568	4.93063059	474	0.969124458	0.087566259	normal	0.715208448	0.409373904	normal	0.964788907	-0.119182225	normal	0.652921643	0.123361611	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12459|0|ptr:452245|SH2B3, LNK; SH2B adaptor protein 3; K12459 SH2B adaptor protein 1/3 (A)"	Neurotrophin signaling pathway (ko04722)	--	--	Phenylalanine zipper;; SH2 domain;; PH domain	SH2B adapter protein 3 GN=SH2B3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SH2B adapter protein 3 isoform X1 [Canis lupus familiaris]
ENSG00000111254(AKAP3)	--	0.153349788	11	0.121490384	9	0.053508013	3	0.01355979	1	0.06604565	4	0.093911439	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16520|0|hsa:10566|AKAP3, AKAP_110, AKAP110, CT82, FSP95, HEL159, PRKA3, SOB1; A kinase (PRKA) anchor protein 3; K16520 A-kinase anchor protein 3 (A)"	--	--	--	A-kinase anchor protein 110 kDa (AKAP 110);; RII binding domain	A-kinase anchor protein 3 GN=AKAP3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 3 isoformX1 [Canis lupus familiaris]
ENSG00000111261(MANSC1)	--	2.875151304	132	3.124752	130	3.171365	141	4.874837009	199	5.044463004	218	5.150558	215	0.551790714	0.556094014	normal	0.123451546	0.717874531	normal	0.402118528	0.595144092	normal	0.030248508	0.628354533	normal	--	--	--	--	--	--	--	MANEC domain	MANSC domain-containing protein 1 (Precursor) GN=MANSC1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: MANSC domain-containing protein 1 [Orycteropus afer afer]
ENSG00000111266(DUSP16)	--	13.56874	1169	8.973814933	852	8.795084879	896	11.501918	1031	14.858527	1483	17.1002015	1616	0.956498175	-0.211766233	normal	0.001009691	0.777108542	normal	0.00010575	0.841492495	normal	0.182785522	0.48168496	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K04459|0|hsa:80824|DUSP16, MKP-7, MKP7; dual specificity phosphatase 16 (EC:3.1.3.16 3.1.3.48); K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 16 GN=DUSP16 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 16 [Ceratotherium simum simum]
ENSG00000111269(CREBL2)	--	19.39699	1026	18.85763	934	18.50422	950	24.47268	1312	24.16171	1153	25.39234	1320	0.880874249	0.323475474	normal	0.92005392	0.282059813	normal	0.479040382	0.465615538	normal	0.028452026	0.358009211	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	Basic region leucine zipper;; bZIP transcription factor	cAMP-responsive element-binding protein-like 2 GN=CREBL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cAMP responsive element binding protein-like 2 [Canis lupus familiaris] 
ENSG00000111271(ACAD10)	--	56.54311463	1994	46.57971007	1695	46.46615077	1763	97.42448955	3293	97.63217246	3341	85.38376385	3120	0.006112172	0.692485644	normal	2.04E-06	0.956948823	normal	0.000164372	0.814689787	normal	1.70E-09	0.817836118	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K11729|0|hsa:80724|ACAD10; acyl-CoA dehydrogenase family, member 10 (EC:1.2.1.3); K11729 acyl-CoA dehydrogenase family member 10 (A)"	--	[R]	General function prediction only	"Phosphotransferase enzyme family;; Acyl-CoA dehydrogenase, C-terminal domain;; Haloacid dehalogenase-like hydrolase;; Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, middle domain;; Ecdysteroid kinase"	Acyl-CoA dehydrogenase family member 10 GN=ACAD10 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-CoA dehydrogenase family member 10 [Vicugna pacos]
ENSG00000111276(CDKN1B)	--	15.66470422	667	15.86784245	680	14.62716165	606	15.08779541	644	19.86060838	844	21.72590553	933	0.971717472	-0.081267803	normal	0.906206136	0.289702427	normal	0.057498999	0.61302563	normal	0.281185526	0.289664845	normal	--	--	Molecular Function: cyclin-dependent protein serine/threonine kinase inhibitor activity (GO:0004861);; Cellular Component: nucleus (GO:0005634);; Biological Process: cell cycle arrest (GO:0007050);; 	"K06624|3.32945e-116|ptr:466947|CDKN1B; cyclin-dependent kinase inhibitor 1B (p27, Kip1); K06624 cyclin-dependent kinase inhibitor 1B (A)"	HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; PI3K-Akt signaling pathway (ko04151);; Hepatitis B (ko05161);; Measles (ko05162);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Cyclin-dependent kinase inhibitor	Cyclin-dependent kinase inhibitor 1B GN=CDKN1B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cyclin-dependent kinase inhibitor 1B [Loxodonta africana]
ENSG00000111291(GPRC5D)	--	0.211191806	2	1.747452981	11	0.309712	2	0.820662	9	0.531241007	3	1.651354793	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04621|0|hsa:55507|GPRC5D; G protein-coupled receptor, class C, group 5, member D; K04621 G protein-coupled receptor family C group 5 member D (A)"	--	--	--	7 transmembrane sweet-taste receptor of 3 GCPR	G-protein coupled receptor family C group 5 member D GN=GPRC5D OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor family C group 5 member D [Elephantulus edwardii]
ENSG00000111300(NAA25)	--	14.8102	1482	14.9835	1397	14.450793	1410	13.928328	1398	14.15048	1416	13.37329	1340	0.978977489	-0.114890685	normal	0.982967435	-0.001935232	normal	0.980914414	-0.081663746	normal	0.787866539	-0.067460216	normal	--	--	--	"K17973|0|hsa:80018|NAA25, C12orf30, MDM20, NAP1; N(alpha)-acetyltransferase 25, NatB auxiliary subunit; K17973 N-terminal acetyltransferase B complex non-catalytic subunit (A)"	--	[Z]	Cytoskeleton	N-acetyltransferase B complex (NatB) non catalytic subunit;; Tetratricopeptide repeat	"N-alpha-acetyltransferase 25, NatB auxiliary subunit GN=NAA25 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: N-alpha-acetyltransferase 25, NatB auxiliary subunit [Tupaia chinensis]"
ENSG00000111305(GSG1)	--	0	0	0	0	0	0	0.494846787	9	0.080538934	1	0.2026163	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	GSG1-like protein;; PMP-22/EMP/MP20/Claudin tight junction;; PMP-22/EMP/MP20/Claudin family	Germ cell-specific gene 1 protein GN=GSG1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: germ cell-specific gene 1 protein isoform X2 [Galeopterus variegatus]
ENSG00000111319(SCNN1A)	--	4.561085074	279	3.400501301	219	3.552308	220	2.650245172	160	5.915621	348	3.9492545	242	0.009927246	-0.82692959	normal	0.126118137	0.643177389	normal	0.959986737	0.12837045	normal	0.965475915	0.042852242	normal	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	K04824|0|ggo:101149563|SCNN1A; amiloride-sensitive sodium channel subunit alpha; K04824 amiloride-sensitive sodium channel subunit alpha (A)	Taste transduction (ko04742);; Aldosterone-regulated sodium reabsorption (ko04960)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Amiloride-sensitive sodium channel subunit alpha GN=SCNN1A OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: amiloride-sensitive sodium channel subunit alpha [Ceratotherium simum simum]
ENSG00000111321(LTBR)	--	101.30178	4222	101.158238	4226	96.740619	4157	85.715666	3617	103.9641251	4314	116.797065	4871	0.970471493	-0.253865306	normal	0.992299387	0.00830391	normal	0.980623845	0.220309681	normal	1	0.002065568	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K03159|0|ggo:101149920|LTBR; tumor necrosis factor receptor superfamily member 3 isoform 1; K03159 lymphotoxin beta receptor TNFR superfamily member 3 (A)	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Intestinal immune network for IgA production (ko04672);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 3 (Precursor) GN=LTBR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 3 [Balaenoptera acutorostrata scammoni]
ENSG00000111325(OGFOD2)	--	70.86682685	1745	70.49318917	1864	74.63916574	1900	97.45525744	2458	97.03533037	2353	95.32643606	2271	0.524023729	0.463080605	normal	0.918317165	0.314445396	normal	0.957596925	0.248855447	normal	0.030474631	0.341016794	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 GN=OGFOD2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 [Myotis brandtii] 
ENSG00000111328(CDK2AP1)	--	93.88092785	1926	115.4992367	2410	100.298449	2091	98.33253775	2041	86.82801374	1775	90.58252142	1866	0.986054485	0.052795302	normal	0.551353167	-0.462301213	normal	0.976424062	-0.172403448	normal	0.274478396	-0.199372211	normal	--	--	--	--	--	[TD]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning"	Cyclin-dependent kinase 2-associated protein	Cyclin-dependent kinase 2-associated protein 1 GN=CDK2AP1 OS=Homo sapiens (Human) PE=1 SV=1	DT	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	cyclin-dependent kinase 2 associated protein 1 [Canis lupus familiaris]
ENSG00000111331(OAS3)	--	14.061378	1756	13.909688	1831	18.343119	2010	22.12394	2431	18.02266	2195	22.05637623	2493	0.631648697	0.438097756	normal	0.960364892	0.239981357	normal	0.929400445	0.302191413	normal	0.04066786	0.326059368	normal	--	--	Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K14216|0|hsa:4940|OAS3, p100, p100OAS; 2'-5'-oligoadenylate synthetase 3, 100kDa (EC:2.7.7.84); K14216 2'-5'-oligoadenylate synthetase [EC:2.7.7.84] (A)"	Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	"2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus;; Nucleotidyltransferase domain"	2'-5'-oligoadenylate synthase 3 GN=OAS3 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 2'-5'-oligoadenylate synthase 3 [Galeopterus variegatus]
ENSG00000111335(OAS2)	--	0.032425179	2	0	0	0.0247064	0	0.099154162	5	0.021884822	1	0.066996457	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K14216|0|ptr:739230|OAS2; 2'-5'-oligoadenylate synthetase 2, 69/71kDa; K14216 2'-5'-oligoadenylate synthetase [EC:2.7.7.84] (A)"	Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	"2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus;; Nucleotidyltransferase domain"	2'-5'-oligoadenylate synthase 2 GN=OAS2 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: 2'-5'-oligoadenylate synthase 3 [Ceratotherium simum simum]
ENSG00000111339(ART4)	--	0.01250225	1	0	0	0	0	0.012364283	1	0.023764077	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity (GO:0003956);; Biological Process: protein ADP-ribosylation (GO:0006471);; 	"K06717|0|hsa:420|ART4, ARTC4, CD297, DO, DOK1; ADP-ribosyltransferase 4 (Dombrock blood group) (EC:2.4.2.31); K06717 ADP-ribosyltransferase 4 [EC:2.4.2.31] (A)"	--	--	--	NAD:arginine ADP-ribosyltransferase	Ecto-ADP-ribosyltransferase 4 (Precursor) GN=ART4 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: ecto-ADP-ribosyltransferase 4 [Balaenoptera acutorostrata scammoni]
ENSG00000111344(RASAL1)	--	0.199329529	14	0.088169253	6	0.231069881	16	0.103458391	7	0.24680766	16	0.25153421	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular signal transduction (GO:0035556);; Biological Process: regulation of GTPase activity (GO:0043087);; 	"K17632|0|hsa:8437|RASAL1, RASAL; RAS protein activator like 1 (GAP1 like); K17632 RAS protein activator-like 1 (A)"	Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; C2 domain;; BTK motif;; PH domain	RasGAP-activating-like protein 1 GN=RASAL1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rasGAP-activating-like protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000111348(ARHGDIB)	--	0.637155195	12	0.56518649	9	0.069454967	0	3.261962373	64	3.269098355	65	1.863694918	43	1.20E-05	2.246725497	up	2.86E-07	2.64190295	up	3.35E-09	4.875399368	up	1.15E-08	3.009150921	up	--	--	Molecular Function: Rho GDP-dissociation inhibitor activity (GO:0005094);; Cellular Component: cytoplasm (GO:0005737);; 	K12462|2.54886e-137|ptr:742002|ARHGDIB; Rho GDP dissociation inhibitor (GDI) beta; K12462 Rho GDP-dissociation inhibitor (A)	Neurotrophin signaling pathway (ko04722);; Vasopressin-regulated water reabsorption (ko04962)	[T]	Signal transduction mechanisms	RHO protein GDP dissociation inhibitor	Rho GDP-dissociation inhibitor 2 GN=ARHGDIB OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho GDP-dissociation inhibitor 2 [Canis lupus familiaris]
ENSG00000111358(GTF2H3)	--	15.93597833	788	14.41349	714	17.48230104	785	20.69402412	1025	22.89636205	1038	17.81461842	849	0.836181152	0.347927875	normal	0.293776126	0.517470033	normal	0.972532657	0.104586675	normal	0.062583578	0.32696729	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Cellular Component: core TFIIH complex (GO:0000439);; Biological Process: nucleotide-excision repair (GO:0006289);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K03143|0|ggo:101141227|GTF2H3; general transcription factor IIH subunit 3 isoform 1; K03143 transcription initiation factor TFIIH subunit 3 (A)	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420);; Viral carcinogenesis (ko05203)	[KL]	"Transcription;; Replication, recombination and repair"	Transcription factor Tfb4	General transcription factor IIH subunit 3 GN=GTF2H3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: general transcription factor IIH subunit 3 [Vicugna pacos]
ENSG00000111361(EIF2B1)	--	20.41185	894	18.334065	840	18.07604	827	23.223351	1069	23.298837	1037	22.76278879	999	0.94866385	0.226726161	normal	0.917174673	0.282070338	normal	0.928416769	0.263866277	normal	0.16337786	0.256425644	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: cellular metabolic process (GO:0044237);; 	"K03239|0|ptr:467184|EIF2B1; eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa; K03239 translation initiation factor eIF-2B subunit alpha (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Initiation factor 2 subunit family	Translation initiation factor eIF-2B subunit alpha GN=EIF2B1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: translation initiation factor eIF-2B subunit alpha [Echinops telfairi]
ENSG00000111364(DDX55)	--	14.40036442	744	14.305586	734	12.648119	672	13.77137	724	14.81727	761	12.89487	682	0.973858125	-0.06999864	normal	0.975229984	0.030627859	normal	0.975038861	0.012990046	normal	0.982536883	-0.010124152	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K14809|0|hsa:57696|DDX55; DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 (EC:3.6.4.13); K14809 ATP-dependent RNA helicase DDX55/SPB4 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Domain of unknown function (DUF4217);; Type III restriction enzyme, res subunit"	ATP-dependent RNA helicase DDX55 GN=DDX55 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX55 isoform X1 [Camelus bactrianus]
ENSG00000111371(SLC38A1)	--	79.45882333	8375	100.8650904	10346	86.55251592	8887	86.88631928	8875	71.70842709	7577	138.2955046	14174	0.995531246	0.052816253	normal	0.713975381	-0.470720245	normal	0.025396009	0.665096705	normal	0.845964132	0.129741883	normal	--	--	--	"K14990|0|ptr:451850|SLC38A1; solute carrier family 38, member 1; K14990 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 1 (A)"	Glutamatergic synapse (ko04724);; GABAergic synapse (ko04727)	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Sodium-coupled neutral amino acid transporter 1 GN=SLC38A1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: sodium-coupled neutral amino acid transporter 1 isoform X2 [Ursus maritimus]
ENSG00000111404(RERGL)	--	0	0	0	0	0	0	0.065466641	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K17198|1.2974e-149|ptr:465320|RERGL; RERG/RAS-like; K17198 Ras-related and estrogen-regulated growth inhibitor-like protein (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein	Ras-related and estrogen-regulated growth inhibitor-like protein GN=RERGL OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ras-related and estrogen-regulated growth inhibitor-like protein-like [Dasypus novemcinctus]
ENSG00000111412(C12orf49)	--	10.05492159	1083	14.84587128	1328	10.12201511	1192	9.27475462	1326	10.33764287	1205	13.78478836	1701	0.936914854	0.260880343	normal	0.970926228	-0.161455446	normal	0.31745462	0.504169284	normal	0.494316834	0.211596718	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2054)	UPF0454 protein C12orf49 (Precursor) GN=C12orf49 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0454 protein C12orf49 homolog [Orcinus orca] 
ENSG00000111424(VDR)	--	1.75815986	177	0.755308773	77	1.855412943	150	3.516037016	348	5.16604211	424	2.877012541	288	0.000520588	0.938592316	normal	0	2.417028274	up	0.001499456	0.925961369	normal	6.83E-05	1.370544479	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08539|0|mcf:102130594|VDR; vitamin D (1,25- dihydroxyvitamin D3) receptor; K08539 vitamin D3 receptor (A)"	Endocrine and other factor-regulated calcium reabsorption (ko04961);; Mineral absorption (ko04978);; Tuberculosis (ko05152)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Vitamin D3 receptor GN=VDR OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	Vitamin D3 receptor [Myotis brandtii]
ENSG00000111432(FZD10)	--	0	0	0	0	0	0	0	0	0	0	0.01729549	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	"K02842|0|hsa:11211|FZD10, CD350, FZ-10, Fz10, FzE7, hFz10; frizzled class receptor 10; K02842 frizzled 9/10 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-10 (Precursor) GN=FZD10 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: frizzled-10 [Odobenus rosmarus divergens] 
ENSG00000111445(RFC5)	--	23.99985426	776	24.40183514	768	26.78094946	870	28.82957159	932	28.41724912	897	20.90694027	679	0.943157003	0.233019607	normal	0.95414596	0.202206396	normal	0.801604803	-0.365174828	normal	0.918920187	0.033276674	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	"K10756|0|pps:100979247|RFC5; replication factor C (activator 1) 5, 36.5kDa; K10756 replication factor C subunit 3/5 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430)	[L]	"Replication, recombination and repair"	"Replication factor C C-terminal domain;; DNA polymerase III, delta subunit;; ATPase family associated with various cellular activities (AAA);; Rad17 cell cycle checkpoint protein;; AAA domain;; Part of AAA domain;; Holliday junction DNA helicase ruvB N-terminus;; Protein of unknown function (DUF815)"	Replication factor C subunit 5 GN=RFC5 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: replication factor C subunit 5 [Galeopterus variegatus]
ENSG00000111450(STX2)	--	19.19401436	1076	19.815921	1098	18.503412	1042	20.60534641	1133	19.99113361	1129	19.78494201	1098	0.980004694	0.043576881	normal	0.980219615	0.018715454	normal	0.978715901	0.067136406	normal	0.883493494	0.04184034	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: membrane (GO:0016020);; 	K08486|0|ptr:737801|STX2; syntaxin 2; K08486 syntaxin 1B/2/3 (A)	SNARE interactions in vesicular transport (ko04130);; Synaptic vesicle cycle (ko04721)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Syntaxin;; SNARE domain	Syntaxin-2 GN=STX2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-2 [Trichechus manatus latirostris]
ENSG00000111452(ADGRD1)	--	0.0777689	4	0.057617075	3	0.186988408	4	0.104875056	7	0.353866592	8	0.407882605	24	--	--	--	--	--	--	0.126532693	2.203561095	normal	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08465|0|ggo:101144179|GPR133; probable G-protein coupled receptor 133 isoform 1; K08465 G protein-coupled receptor 133 (A)	--	--	--	7 transmembrane receptor (Secretin family);; Concanavalin A-like lectin/glucanases superfamily;; Latrophilin/CL-1-like GPS domain;; Slime mold cyclic AMP receptor	Probable G-protein coupled receptor 133 (Precursor) GN=GPR133 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 133 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000111481(COPZ1)	--	155.1766323	3308	141.7622088	3075	142.5389575	3243	173.6493044	3854	175.6698123	3933	142.7050134	3174	0.982260988	0.189483482	normal	0.923478792	0.333471885	normal	0.990411931	-0.039299813	normal	0.393478672	0.165718801	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	Coatomer subunit zeta-1 GN=COPZ1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	coatomer subunit zeta-1 [Bos taurus] 
ENSG00000111490(TBC1D30)	--	0.8055847	82	1.302458321	62	1.252059827	71	0.509619005	54	0.768102427	66	0.797113947	42	0.799599143	-0.619092888	normal	0.973943519	0.067182876	normal	0.708586383	-0.744863508	normal	0.423350791	-0.430007011	normal	[R]	General function prediction only	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	TBC1 domain family member 30 GN=TBC1D30 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 30 [Orycteropus afer afer]
ENSG00000111530(CAND1)	--	39.7399912	4512	39.80110691	4630	43.226604	4556	43.8865383	4833	44.98900453	5122	37.97821662	4356	0.992367841	0.068297191	normal	0.99054239	0.124229912	normal	0.991944465	-0.073030441	normal	0.880654591	0.04171283	normal	--	--	--	K17263|0|umr:103656854|CAND1; cullin-associated and neddylation-dissociated 1; K17263 cullin-associated NEDD8-dissociated protein 1 (A)	--	[R]	General function prediction only	TATA-binding protein interacting (TIP20);; HEAT repeats;; HEAT repeat;; HEAT-like repeat;; UME (NUC010) domain;; Vacuolar 14 Fab1-binding region;; non-SMC mitotic condensation complex subunit 1;; CLASP N terminal;; Adaptin N terminal region;; RNAPII transcription regulator C-terminal;; Domain of unknown function (DUF1981)	Cullin-associated NEDD8-dissociated protein 1 GN=CAND1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cullin-associated NEDD8-dissociated protein 1 [Orycteropus afer afer]
ENSG00000111540(RAB5B)	--	37.802861	2136	37.44328014	2103	40.58213557	2189	41.81513304	2287	36.13832049	1971	42.64970098	2373	0.986616015	0.067665414	normal	0.98291465	-0.114862292	normal	0.984940253	0.108076975	normal	0.937734595	0.023771288	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07888|4.81009e-150|ptr:746457|RAB5B; RAB5B, member RAS oncogene family; K07888 Ras-related protein Rab-5B (A)"	Ras signaling pathway (ko04014);; Endocytosis (ko04144);; Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Amoebiasis (ko05146);; Tuberculosis (ko05152)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase	Ras-related protein Rab-5B GN=RAB5B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-5B isoform X1 [Sus scrofa]
ENSG00000111554(MDM1)	--	5.830827294	402	5.834865596	381	6.439626843	438	6.681249922	449	5.992382507	352	5.75036171	424	0.962035683	0.12822383	normal	0.959130789	-0.135084104	normal	0.969079762	-0.05496515	normal	0.972572149	-0.016540806	normal	--	--	Molecular Function: microtubule binding (GO:0008017);; Biological Process: negative regulation of centriole replication (GO:0046600);; 	K17886|0|ptr:741475|MDM1; Mdm1 nuclear protein homolog (mouse); K17886 nuclear protein MDM1 (A)	--	--	--	Nuclear protein MDM1	Nuclear protein MDM1 GN=MDM1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: nuclear protein MDM1 isoform X2 [Galeopterus variegatus]
ENSG00000111581(NUP107)	--	27.93329131	1601	27.91194284	1669	29.58881113	1693	33.09590527	1939	30.51475516	1757	27.37107784	1605	0.954820802	0.245293078	normal	0.984227941	0.052657175	normal	0.982802723	-0.085221923	normal	0.758315786	0.073339733	normal	--	--	Cellular Component: nuclear pore (GO:0005643);; Biological Process: transport (GO:0006810);; 	"K14301|0|hsa:57122|NUP107, NUP84; nucleoporin 107kDa; K14301 nuclear pore complex protein Nup107 (A)"	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Nuclear pore protein 84 / 107	Nuclear pore complex protein Nup107 GN=NUP107 OS=Homo sapiens (Human) PE=1 SV=1	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup107 [Tursiops truncatus]
ENSG00000111596(CNOT2)	--	25.2463293	1061	24.848912	1018	25.81378888	1019	26.25629864	1186	32.289252	1339	30.08521348	1230	0.973996989	0.129669432	normal	0.802729396	0.373506699	normal	0.934193372	0.262857261	normal	0.149487793	0.2564239	normal	[K]	Transcription	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K12605|0|umr:103656881|CNOT2; CCR4-NOT transcription complex, subunit 2; K12605 CCR4-NOT transcription complex subunit 2 (A)"	RNA degradation (ko03018)	[KDR]	"Transcription;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	NOT2 / NOT3 / NOT5 family	CCR4-NOT transcription complex subunit 2 GN=CNOT2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 2 isoform 1 [Ceratotherium simum simum]
ENSG00000111602(TIMELESS)	--	26.9593513	2768	27.08600567	2844	27.56374621	2873	24.27455533	2489	25.18605041	2568	27.666871	2857	0.978826142	-0.1840022	normal	0.981165825	-0.168608417	normal	0.989830198	-0.016339774	normal	0.565217571	-0.121249031	normal	--	--	--	"K03155|0|hsa:8914|TIMELESS, TIM, TIM1, hTIM; timeless circadian clock; K03155 timeless (A)"	--	[L]	"Replication, recombination and repair"	Timeless protein C terminal region;; Timeless protein	Protein timeless homolog OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: protein timeless homolog [Ceratotherium simum simum]
ENSG00000111605(CPSF6)	--	34.86655714	1893	34.2355256	1870	31.58493668	1710	39.11528728	2013	40.37575297	2116	33.86802784	1943	0.985749768	0.057795007	normal	0.978483859	0.156755571	normal	0.974613001	0.175852146	normal	0.537346104	0.128418042	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K14398|1.62419e-160|mcc:718331|cleavage and polyadenylation specificity factor subunit 6-like; K14398 cleavage and polyadenylation specificity factor subunit 6/7 (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Cleavage and polyadenylation specificity factor subunit 6 GN=CPSF6 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: cleavage and polyadenylation specificity factor subunit 6 isoform X1 [Elephantulus edwardii]
ENSG00000111615(KRR1)	--	32.14997001	1720	31.31567191	1750	34.44118779	1839	26.27956193	2353	24.75796392	2091	27.04469228	1954	0.6939692	0.420937877	normal	0.960916167	0.23522542	normal	0.984626643	0.07915439	normal	0.148694039	0.247511537	normal	[R]	General function prediction only	--	K06961|0|ggo:101154395|KRR1; KRR1 small subunit processome component homolog; K06961 ribosomal RNA assembly protein (A)	--	[JD]	"Translation, ribosomal structure and biogenesis;; Cell cycle control, cell division, chromosome partitioning"	KH domain;; KH domain	KRR1 small subunit processome component homolog GN=KRR1 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: KRR1 small subunit processome component homolog isoform X1 [Galeopterus variegatus]
ENSG00000111639(MRPL51)	--	93.41385	1440	92.17813	1435	96.06614	1548	103.91011	1697	93.718563	1396	107.13125	1559	0.96534996	0.205882969	normal	0.981837463	-0.061113052	normal	0.984438216	0.001922143	normal	0.843613641	0.051429706	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; 	K17432|3.76137e-88|pps:100979044|MRPL51; mitochondrial ribosomal protein L51; K17432 large subunit ribosomal protein L51 (A)	--	[S]	Function unknown	Mitochondrial ribosomal subunit	"39S ribosomal protein L51, mitochondrial (Precursor) GN=MRPL51 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L51, mitochondrial [Galeopterus variegatus]"
ENSG00000111640(GAPDH)	--	4265.19024	100876	4023.38662	97022	3978.704216	95276	4486.985352	108720	3578.95296	83556	3941.66568	95085	0.999431345	0.07720099	normal	0.998016005	-0.236991063	normal	0.999441803	-0.011186341	normal	0.895946735	-0.050666811	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor (GO:0016620);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00134|0|ptr:451783|GAPDH, GAPD; glyceraldehyde-3-phosphate dehydrogenase; K00134 glyceraldehyde 3-phosphate dehydrogenase [EC:1.2.1.12] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; HIF-1 signaling pathway (ko04066);; Alzheimer's disease (ko05010)	[G]	Carbohydrate transport and metabolism	"Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain;; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain"	Glyceraldehyde-3-phosphate dehydrogenase GN=GAPDH OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	glyceraldehyde 3-phosphate dehydrogenase [Sus scrofa]
ENSG00000111641(NOP2)	--	27.68837721	1622	24.72264941	1484	28.04275902	1699	29.43842982	1818	32.52713724	2037	27.76027403	1731	0.979436565	0.133626517	normal	0.647595473	0.43514841	normal	0.985332134	0.018612017	normal	0.286545473	0.196203197	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; 	"K14835|0|hsa:4839|NOP2, NOL1, NOP120, NSUN1, p120; NOP2 nucleolar protein; K14835 ribosomal RNA methyltransferase Nop2 [EC:2.1.1.-] (A)"	--	[A]	RNA processing and modification	NOL1/NOP2/sun family;; P120R (NUC006) repeat;; Putative binding domain;; FtsJ-like methyltransferase	Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase GN=NOP2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: putative ribosomal RNA methyltransferase NOP2 [Galeopterus variegatus]
ENSG00000111642(CHD4)	--	36.464998	5704	33.154079	5268	35.9908344	5672	38.29489118	5985	42.68951719	6591	27.704891	4221	0.994026182	0.038534869	normal	0.9633133	0.301737888	normal	0.746066609	-0.434429368	normal	0.987290824	-0.008737315	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: histone deacetylation (GO:0016575);; Molecular Function: hydrolase activity (GO:0016787);; Cellular Component: HDA1 complex (GO:0070823);; 	K11643|0|ptg:102959414|CHD4; chromodomain helicase DNA binding protein 4; K11643 chromodomain-helicase-DNA-binding protein 4 [EC:3.6.4.12] (A)	Viral carcinogenesis (ko05203)	[R]	General function prediction only	"CHDCT2 (NUC038) domain;; Domain of Unknown Function (DUF1086);; SNF2 family N-terminal domain;; CHDNT (NUC034) domain;; Domain of Unknown Function (DUF1087);; PHD-finger;; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain;; Class II histone deacetylase complex subunits 2 and 3;; Type III restriction enzyme, res subunit"	Chromodomain-helicase-DNA-binding protein 4 GN=CHD4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: chromodomain-helicase-DNA-binding protein 4 isoform 1 [Odobenus rosmarus divergens]
ENSG00000111644(ACRBP)	--	0.030040263	1	0.26769157	10	0.205604063	3	0.157636475	3	0.257533268	4	0.312190502	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Proacrosin binding protein sp32	Acrosin-binding protein (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: acrosin-binding protein [Ailuropoda melanoleuca] 
ENSG00000111647(UHRF1BP1L)	--	5.980628686	629	7.11605553	731	6.419162823	686	8.199848803	885	7.5097536	790	7.038447	731	0.5053633	0.460832175	normal	0.972295256	0.090374815	normal	0.97261272	0.083193698	normal	0.306235329	0.212032266	normal	--	--	--	--	--	[S]	Function unknown	"N-terminal region of Chorein, a TM vesicle-mediated sorter"	UHRF1-binding protein 1-like GN=UHRF1BP1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UHRF1-binding protein 1-like [Ceratotherium simum simum]
ENSG00000111652(COPS7A)	--	31.78805986	986	29.60383278	975	34.09767481	1018	31.37879331	958	32.37708092	1021	32.27646174	1035	0.977187005	-0.072279981	normal	0.978304064	0.045013955	normal	0.979829038	0.015578812	normal	0.992194587	-0.004017067	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12180|1.49703e-180|umr:103656190|COPS7A; COP9 signalosome subunit 7A; K12180 COP9 signalosome complex subunit 7 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PCI domain	COP9 signalosome complex subunit 7a GN=COPS7A OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: COP9 signalosome complex subunit 7a [Erinaceus europaeus]
ENSG00000111653(ING4)	--	9.182287609	229	10.52460012	245	10.94328681	273	10.34555881	248	9.36208282	230	9.991862062	258	0.964179593	0.083621077	normal	0.960602571	-0.111861648	normal	0.963949432	-0.089312322	normal	0.927998106	-0.042263888	normal	--	--	--	"K11346|1.14321e-149|nle:100588102|ING4; inhibitor of growth family, member 4; K11346 inhibitor of growth protein 4 (A)"	--	[B]	Chromatin structure and dynamics	Inhibitor of growth proteins N-terminal histone-binding;; PHD-finger	Inhibitor of growth protein 4 GN=ING4 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: inhibitor of growth protein 4 isoform X1 [Loxodonta africana] 
ENSG00000111664(GNB3)	--	0.664355927	19	0.695427177	23	0.762447	26	0.660905867	22	0.304289692	10	0.834160779	25	0.988172559	0.168037186	normal	0.903405939	-1.109689264	normal	0.98634879	-0.06124203	normal	0.784351403	-0.275270806	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K07825|0|pps:100968267|GNB3; guanine nucleotide binding protein (G protein), beta polypeptide 3; K07825 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Taste transduction (ko04742);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[R]	General function prediction only	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 GN=GNB3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3 [Pteropus alecto] 
ENSG00000111665(CDCA3)	--	19.59883002	656	20.21267477	622	20.41096453	654	22.74932064	737	20.54054006	655	19.12974417	617	0.966244284	0.136834077	normal	0.972544061	0.053028126	normal	0.97056869	-0.092092309	normal	0.912679609	0.034686675	normal	--	--	--	--	--	--	--	--	Cell division cycle-associated protein 3 GN=CDCA3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cell division cycle-associated protein 3 [Balaenoptera acutorostrata scammoni]
ENSG00000111666(CHPT1)	--	64.32291	1300	62.3441	1293	58.82815	1202	51.85179	1066	48.82732	997	54.18812	1113	0.889476793	-0.316722256	normal	0.746814981	-0.395954389	normal	0.97571324	-0.119118956	normal	0.109006295	-0.278113902	normal	[I]	Lipid transport and metabolism	"Biological Process: phospholipid biosynthetic process (GO:0008654);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, for other substituted phosphate groups (GO:0016780);; "	"K00994|0|hsa:56994|CHPT1, CPT, CPT1; choline phosphotransferase 1 (EC:2.7.8.2); K00994 diacylglycerol cholinephosphotransferase [EC:2.7.8.2] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	CDP-alcohol phosphatidyltransferase	Cholinephosphotransferase 1 GN=CHPT1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: cholinephosphotransferase 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000111667(USP5)	--	47.57035889	2718	53.87905492	2757	59.08558	2903	47.74525189	2910	47.588324	2814	42.06573	2389	0.988763916	0.067604498	normal	0.989363112	0.00809211	normal	0.944279536	-0.289262773	normal	0.782698417	-0.068010328	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11836|0|ptr:451798|USP5; ubiquitin specific peptidase 5 (isopeptidase T); K11836 ubiquitin carboxyl-terminal hydrolase 5/13 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; UBA/TS-N domain;; Zn-finger in ubiquitin-hydrolases and other protein;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 5 GN=USP5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 5 isoform 1 [Dasypus novemcinctus]
ENSG00000111669(TPI1)	--	665.004339	15404	637.0768084	14949	678.809218	15852	878.34904	20391	661.286843	15180	735.404442	16990	0.956469556	0.373762745	normal	0.997222315	0.000696183	normal	0.99702482	0.091721085	normal	0.475738105	0.16415085	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: triose-phosphate isomerase activity (GO:0004807);; Biological Process: metabolic process (GO:0008152);; 	K01803|0|nle:100593490|TPI1; triosephosphate isomerase 1; K01803 triosephosphate isomerase (TIM) [EC:5.3.1.1] (A)	Glycolysis / Gluconeogenesis (ko00010);; Fructose and mannose metabolism (ko00051);; Inositol phosphate metabolism (ko00562);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Triosephosphate isomerase	Triosephosphate isomerase GN=TPI1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: triosephosphate isomerase [Pteropus alecto]
ENSG00000111670(GNPTAB)	--	13.46286336	1370	13.1956222	1357	12.81802649	1271	17.63071806	1806	16.70410403	1674	15.43160101	1609	0.823378828	0.367429879	normal	0.932096386	0.281169689	normal	0.879275394	0.331557458	normal	0.042413982	0.326432265	normal	--	--	"Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	"K08239|0|hsa:79158|GNPTAB, GNPTA, ICD; N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits (EC:2.7.8.17); K08239 UDP-N-acetylglucosamine-lysosomal-enzyme [EC:2.7.8.17] (A)"	Lysosome (ko04142)	--	--	DMAP1-binding Domain;; LNR domain;; Protein of unknown function (DUF3184)	N-acetylglucosamine-1-phosphotransferase subunit beta (Precursor) GN=GNPTAB OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: N-acetylglucosamine-1-phosphotransferase subunits alpha/beta [Equus przewalskii]
ENSG00000111671(SPSB2)	--	15.89347	334	11.55894	258	12.33264051	279	12.86788	282	15.05205	320	13.91104	302	0.915423249	-0.273613399	normal	0.907511597	0.287757286	normal	0.962728193	0.105442521	normal	0.945949457	0.032664665	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10344|1.33257e-180|pps:100969185|SPSB2; splA/ryanodine receptor domain and SOCS box containing 2; K10344 SPRY domain-containing SOCS box protein 2 (A)	--	[R]	General function prediction only	SPRY domain	SPRY domain-containing SOCS box protein 2 GN=SPSB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SPRY domain-containing SOCS box protein 2 isoform X3 [Equus przewalskii]
ENSG00000111676(ATN1)	--	24.95029	2378	28.57529	2704	27.29351	2651	26.10475	2440	25.33669	2391	31.15093	2966	0.988503104	0.006296153	normal	0.975713718	-0.198789257	normal	0.983507641	0.153607603	normal	0.97937144	-0.008685281	normal	--	--	--	"K05626|0|hsa:1822|ATN1, B37, D12S755E, DRPLA, HRS, NOD; atrophin 1; K05626 atrophin-1 (dentatorubral-pallidoluysian atrophy protein) (A)"	--	[R]	General function prediction only	Atrophin-1 family	Atrophin-1 GN=ATN1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: atrophin-1 isoform X3 [Mustela putorius furo] 
ENSG00000111678(C12orf57)	--	225.5404404	1185	214.8320493	1143	185.7338834	1015	165.7350589	934	192.0945833	1007	214.001832	1153	0.789508628	-0.373677625	normal	0.958462748	-0.203900627	normal	0.966047565	0.175376029	normal	0.542395782	-0.132455012	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4511)	Protein C10 GN=C12orf57 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PANDA_011242 [Ailuropoda melanoleuca]
ENSG00000111679(PTPN6)	--	11.75029176	543	9.389005403	448	9.82761125	468	10.33537129	427	9.904191483	457	10.89338472	484	0.784433913	-0.376344176	normal	0.97001883	0.007244662	normal	0.970644634	0.040079718	normal	0.693737403	-0.113772889	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K05697|0|pps:100990286|PTPN6; protein tyrosine phosphatase, non-receptor type 6; K05697 tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48] (A)"	Adherens junction (ko04520);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Leishmaniasis (ko05140);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; SH2 domain;; Dual specificity phosphatase, catalytic domain"	Tyrosine-protein phosphatase non-receptor type 6 GN=PTPN6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 6 [Loxodonta africana]
ENSG00000111684(LPCAT3)	--	24.4824	896	20.3694	746	22.3764	817	24.8417	906	30.5904	1108	31.3935	1151	0.978251651	-0.014794717	normal	0.188366556	0.548366162	normal	0.395223733	0.485427809	normal	0.060302993	0.343725761	normal	[S]	Function unknown	--	"K13515|0|hsa:10162|LPCAT3, C3F, LPCAT, LPLAT_5, LPSAT, MBOAT5, OACT5, nessy; lysophosphatidylcholine acyltransferase 3 (EC:2.3.1.23 2.3.1.n6); K13515 lysophospholipid acyltransferase 5 [EC:2.3.1.23 2.3.1.-] (A)"	Glycerophospholipid metabolism (ko00564)	[S]	Function unknown	"MBOAT, membrane-bound O-acyltransferase family"	Lysophospholipid acyltransferase 5 GN=LPCAT3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lysophospholipid acyltransferase 5 [Tupaia chinensis]
ENSG00000111696(NT5DC3)	--	5.165644	613	4.290009131	513	4.374803352	529	5.050126	589	4.25877823	509	4.45383	535	0.970134157	-0.088226083	normal	0.970811596	-0.03262318	normal	0.972446607	0.007957108	normal	0.904075273	-0.040914866	normal	--	--	--	--	--	[F]	Nucleotide transport and metabolism	5' nucleotidase family	5'-nucleotidase domain-containing protein 3 GN=NT5DC3 OS=Homo sapiens (Human) PE=2 SV=1	F	Nucleotide transport and metabolism	PREDICTED: 5'-nucleotidase domain-containing protein 3-like isoform X1 [Sus scrofa]
ENSG00000111700(SLCO1B3)	--	15.18707239	561	16.1779396	612	20.57562691	738	40.35616839	1524	29.54767673	1093	30.95805324	1160	4.53E-14	1.408523486	up	0.000527098	0.813738657	normal	0.026552377	0.643080825	normal	9.93E-05	0.961155144	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K05043|0|hsa:28234|SLCO1B3, HBLRR, LST-2, LST-3TM13, LST3, OATP-8, OATP1B3, OATP8, SLC21A8; solute carrier organic anion transporter family, member 1B3; K05043 solute carrier organic anion transporter family, member 1B (A)"	Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain	Solute carrier organic anion transporter family member 1B3 GN=SLCO1B3 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 1B3-like [Galeopterus variegatus]
ENSG00000111704(NANOG)	--	0	0	0	0	0	0	0	0	0.202249372	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K10164|0|pps:100988765|NANOG; Nanog homeobox; K10164 homeobox protein Nanog (A)	Signaling pathways regulating pluripotency of stem cells (ko04550);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	"Homeobox domain;; Homeodomain leucine-zipper encoding, Homez"	Homeobox protein NANOG GN=NANOG OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein NANOG isoform X1 [Galeopterus variegatus]
ENSG00000111707(SUDS3)	--	12.8111	1069	12.341	1040	13.2626	1102	13.0266	1094	13.7973	1144	11.9719	998	0.980448086	0.002515048	normal	0.974775606	0.115916215	normal	0.970078973	-0.151085974	normal	0.979218376	-0.010137255	normal	--	--	--	--	--	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	Sds3-like	Sin3 histone deacetylase corepressor complex component SDS3 GN=SUDS3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: sin3 histone deacetylase corepressor complex component SDS3 [Condylura cristata]
ENSG00000111711(GOLT1B)	--	29.77612006	1131	37.37520013	1341	29.88799505	1097	31.94793228	1204	31.68218039	1161	45.61676202	1225	0.980062082	0.059326084	normal	0.953282553	-0.22908988	normal	0.971661557	0.150730057	normal	0.971712671	-0.012935382	normal	--	--	Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[P]	Inorganic ion transport and metabolism	Got1/Sft2-like family	Vesicle transport protein GOT1B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: vesicle transport protein GOT1B, partial [Elephantulus edwardii]"
ENSG00000111713(GYS2)	--	0.070034	4	0.0349588	2	0.0349623	1	0.0699432	4	0.0170884	0	0.0524458	3	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: glycogen (starch) synthase activity (GO:0004373);; Biological Process: glycogen biosynthetic process (GO:0005978);; 	K00693|0|hsa:2998|GYS2; glycogen synthase 2 (liver) (EC:2.4.1.11); K00693 glycogen(starch) synthase [EC:2.4.1.11] (A)	Starch and sucrose metabolism (ko00500);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Glycogen synthase;; Glycosyl transferases group 1	"Glycogen [starch] synthase, liver GN=GYS2 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: glycogen [starch] synthase, liver [Eptesicus fuscus]"
ENSG00000111716(LDHB)	--	841.163574	17787	840.77573	18012	866.43158	18243	853.1662202	18223	807.1676601	16901	816.8800469	17160	0.997728094	0.004104669	normal	0.996796641	-0.11326651	normal	0.997152003	-0.096576628	normal	0.811872917	-0.069073571	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00016|0|mcc:696935|LDHB; lactate dehydrogenase B-like; K00016 L-lactate dehydrogenase [EC:1.1.1.27] (A)	Glycolysis / Gluconeogenesis (ko00010);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640)	[C]	Energy production and conversion	"lactate/malate dehydrogenase, NAD binding domain;; lactate/malate dehydrogenase, alpha/beta C-terminal domain"	L-lactate dehydrogenase B chain GN=LDHB OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: L-lactate dehydrogenase B chain [Elephantulus edwardii] 
ENSG00000111725(PRKAB1)	--	14.37346192	636	14.75257657	663	14.1353469	641	18.29343185	792	23.52129561	848	18.02183242	754	0.907593999	0.285023388	normal	0.859315988	0.332955831	normal	0.943058897	0.225457788	normal	0.1434328	0.282050916	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K07199|0|ptr:452297|PRKAB1; protein kinase, AMP-activated, beta 1 non-catalytic subunit; K07199 5'-AMP-activated protein kinase, regulatory beta subunit (A)"	FoxO signaling pathway (ko04068);; AMPK signaling pathway (ko04152);; Circadian rhythm (ko04710);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Oxytocin signaling pathway (ko04921);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hypertrophic cardiomyopathy (HCM) (ko05410)	[G]	Carbohydrate transport and metabolism	"5'-AMP-activated protein kinase beta subunit, interation domain"	5'-AMP-activated protein kinase subunit beta-1 GN=PRKAB1 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: 5'-AMP-activated protein kinase subunit beta-1 [Mustela putorius furo] 
ENSG00000111726(CMAS)	--	37.23347648	1151	36.465107	1139	34.14969377	1067	38.58104	1107	37.48698	981	28.64114671	880	0.97811544	-0.086946514	normal	0.946519041	-0.236530497	normal	0.914177617	-0.285829376	normal	0.305214581	-0.199696048	normal	--	--	--	"K00983|0|hsa:55907|CMAS, CSS; cytidine monophosphate N-acetylneuraminic acid synthetase (EC:2.7.7.43); K00983 N-acylneuraminate cytidylyltransferase [EC:2.7.7.43] (A)"	Amino sugar and nucleotide sugar metabolism (ko00520)	--	--	Cytidylyltransferase;; MobA-like NTP transferase domain	N-acylneuraminate cytidylyltransferase GN=CMAS OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: N-acylneuraminate cytidylyltransferase [Galeopterus variegatus]
ENSG00000111727(HCFC2)	--	2.2718505	236	3.282697963	315	2.257257	243	2.41640163	244	2.411732713	263	2.88141288	289	0.96695296	0.017152207	normal	0.912006011	-0.280240886	normal	0.933472795	0.240447997	normal	0.976165213	-0.017325968	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K14966|0|hsa:29915|HCFC2, HCF-2, HCF2; host cell factor C2; K14966 host cell factor (A)"	Herpes simplex infection (ko05168)	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	"Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Fibronectin type III domain"	Host cell factor 2 GN=HCFC2 OS=Homo sapiens (Human) PE=1 SV=1	DK	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	PREDICTED: host cell factor 2 [Orcinus orca]
ENSG00000111728(ST8SIA1)	--	0.13980731	5	0.127241006	2	0.0726005	1	0.17813792	9	0.16065967	7	0.063902798	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03371|0|pps:100970748|ST8SIA1; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; K03371 alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8A) [EC:2.4.99.8] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601);; Glycosphingolipid biosynthesis - globo series (ko00603);; Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase GN=ST8SIA1 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase isoform 1 [Canis lupus familiaris]"
ENSG00000111729(CLEC4A)	--	0.311069232	5	0.166361788	3	0	0	0.061673965	1	0.060681276	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10057|3.98199e-153|hsa:50856|CLEC4A, CLECSF6, DCIR, DDB27, LLIR; C-type lectin domain family 4, member A; K10057 C-type lectin domain family 4 member A (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 4 member A GN=CLEC4A OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 4 member A [Tupaia chinensis]
ENSG00000111731(C2CD5)	--	9.453915958	714	9.976704839	774	10.7382962	819	11.58569819	889	10.99215442	791	11.47528712	886	0.909917089	0.284876826	normal	0.976121061	0.00989844	normal	0.973051903	0.104965418	normal	0.570444861	0.1324099	normal	--	--	--	--	--	[R]	General function prediction only	C2 domain;; Putative heavy-metal-binding	C2 domain-containing protein 5 GN=C2CD5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: C2 domain-containing protein 5 isoform 1 [Ceratotherium simum simum]
ENSG00000111732(AICDA)	--	0	0	0	0	0	0	0.604872757	6	0.509094411	4	0.501085799	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	K10989|2.61138e-144|pps:100973347|AICDA; activation-induced cytidine deaminase; K10989 activation-induced cytidine deaminase [EC:3.5.4.38] (A)	Intestinal immune network for IgA production (ko04672);; Primary immunodeficiency (ko05340)	--	--	APOBEC-like N-terminal domain;; APOBEC-like C-terminal domain	Single-stranded DNA cytosine deaminase GN=AICDA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	AID [Pecari tajacu]
ENSG00000111737(RAB35)	--	26.44468581	1379	27.56649127	1430	24.91904894	1324	34.75727696	1899	36.92302	1927	32.61949873	1753	0.641104147	0.430375063	normal	0.73386033	0.408541444	normal	0.751632472	0.396236868	normal	0.006690323	0.411307412	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07876|5.07852e-128|ssc:100151805|RAB35; RAB35, member RAS oncogene family; K07876 Ras-related protein Rab-35 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase	Ras-related protein Rab-35 GN=RAB35 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Rab-35 isoform X1 [Eptesicus fuscus]
ENSG00000111752(PHC1)	--	10.723118	857	11.1081264	855	9.7480992	848	9.675228439	837	10.53022348	876	9.247009379	786	0.975912655	-0.064782317	normal	0.977295069	0.013556204	normal	0.971131794	-0.117608482	normal	0.843252307	-0.056142307	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11456|0|hsa:1911|PHC1, EDR1, HPH1, MCPH11, RAE28; polyhomeotic homolog 1 (Drosophila); K11456 polyhomeotic-like protein 1 (A)"	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; MYM-type Zinc finger with FCS sequence motif	Polyhomeotic-like protein 1 GN=PHC1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: polyhomeotic-like protein 1 [Orycteropus afer afer]
ENSG00000111775(COX6A1)	--	410.5100311	3307	400.9582853	3265	402.3093005	3412	451.6397579	3842	451.452171	3653	502.4344324	4014	0.982776926	0.185422233	normal	0.986650198	0.140510653	normal	0.976495251	0.226039065	normal	0.332687579	0.184059796	normal	--	--	Molecular Function: cytochrome-c oxidase activity (GO:0004129);; Cellular Component: mitochondrial inner membrane (GO:0005743);; Cellular Component: mitochondrial respiratory chain complex IV (GO:0005751);; 	"K02266|1.13245e-62|ggo:101131776|cytochrome c oxidase subunit 6A1, mitochondrial-like isoform 1; K02266 cytochrome c oxidase subunit 6a (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome c oxidase subunit VIa	"Cytochrome c oxidase subunit 6A1, mitochondrial (Precursor) GN=COX6A1 OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"Cytochrome c oxidase subunit 6A1, mitochondrial [Tupaia chinensis]"
ENSG00000111783(RFX4)	--	0.018675271	1	0.018689273	1	0	0	0	0	0.015335185	0	0.015636282	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09174|0|pps:100970079|RFX4; regulatory factor X, 4 (influences HLA class II expression); K09174 regulatory factor X 4 (A)"	--	[K]	Transcription	RFX DNA-binding domain;; Poxvirus D5 protein-like	Transcription factor RFX4 GN=RFX4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor RFX4 isoform 1 [Trichechus manatus latirostris]
ENSG00000111785(RIC8B)	--	6.528032032	424	7.372117291	451	8.179916272	529	6.970090627	479	7.493166955	464	7.165011166	453	0.959967619	0.14463583	normal	0.969980566	0.01950633	normal	0.936215751	-0.231332699	normal	0.940739805	-0.029263614	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Guanine nucleotide exchange factor synembryn	Synembryn-B GN=RIC8B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: synembryn-B isoform X1 [Ursus maritimus]
ENSG00000111786(SRSF9)	--	133.87346	2489	136.7684	2646	127.31455	2439	179.03834	3388	158.36789	2915	143.98541	2680	0.753834367	0.41381569	normal	0.986028048	0.118191889	normal	0.984782995	0.127576314	normal	0.202172421	0.224110769	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12890|4.26653e-119|ptr:742440|SRSF9, SFRS9; serine/arginine-rich splicing factor 9; K12890 splicing factor, arginine/serine-rich 1/9 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Serine/arginine-rich splicing factor 9 GN=SRSF9 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 9 [Odobenus rosmarus divergens] 
ENSG00000111790(FGFR1OP2)	--	10.47061359	398	9.831452935	399	11.33482438	440	13.69199407	485	14.90029328	476	12.36966407	430	0.92452511	0.253496447	normal	0.934408233	0.232339174	normal	0.96975942	-0.041314661	normal	0.595179408	0.147929343	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF837)	FGFR1 oncogene partner 2 GN=FGFR1OP2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: FGFR1 oncogene partner 2 homolog isoform 1 [Trichechus manatus latirostris]
ENSG00000111799(COL12A1)	--	5.437472594	1094	3.308736579	787	3.795790132	849	3.523908633	743	4.423727003	878	4.715920248	1031	0.083305031	-0.588001913	normal	0.968401586	0.136182906	normal	0.924076214	0.271476968	normal	0.891433938	-0.062123818	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08132|0|hsa:1303|COL12A1, BA209D8.1, COL12A1L, DJ234P15.1; collagen, type XII, alpha 1; K08132 collagen, type XII, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	"Fibronectin type III domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; Interferon-alpha/beta receptor, fibronectin type III;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; Uncharacterised conserved protein (DUF2369)"	Collagen alpha-1(XII) chain (Precursor) GN=COL12A1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(XII) chain [Pteropus alecto]
ENSG00000111801(BTN3A3)	--	1.620990434	84	1.138466472	55	1.835020242	96	2.951362908	120	2.4459628	139	2.915219348	127	0.848740831	0.476417213	normal	0.000266749	1.293035217	up	0.900596069	0.390072012	normal	0.056788309	0.695664979	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06712|0|ptr:462498|BTN3A3; butyrophilin, subfamily 3, member A3; K06712 butyrophilin (A)"	--	--	--	SPRY domain;; SPRY-associated domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain	Butyrophilin subfamily 3 member A3 (Precursor) GN=BTN3A3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: butyrophilin subfamily 3 member A3-like isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000111802(TDP2)	--	21.57686613	743	27.299034	954	23.4851329	811	25.02890533	872	26.12080052	896	38.60195	1329	0.954506797	0.199752079	normal	0.972927181	-0.111734286	normal	0.005852488	0.703241283	normal	0.502572925	0.284269727	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Endonuclease/Exonuclease/phosphatase family;; UBA-like domain	Tyrosyl-DNA phosphodiesterase 2 GN=TDP2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	tyrosyl-DNA phosphodiesterase 2 [Sus scrofa]
ENSG00000111816(FRK)	--	1.534879621	289	1.96588733	368	1.424945606	263	2.091584321	395	2.306795171	432	2.649141095	497	0.722398432	0.418043267	normal	0.942658938	0.209105204	normal	0.000254181	0.906039157	normal	0.022317097	0.50426678	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08892|0|hsa:2444|FRK, GTK, PTK5, RAK; fyn-related Src family tyrosine kinase (EC:2.7.10.2); K08892 fyn-related kinase [EC:2.7.10.2] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Phosphotransferase enzyme family	Tyrosine-protein kinase FRK GN=FRK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase FRK [Chrysochloris asiatica]
ENSG00000111817(DSE)	--	12.16624436	959	10.85057284	885	10.99966913	862	14.99562445	1205	17.37309045	1372	15.10284461	1211	0.905980571	0.298171251	normal	0.05849192	0.610260796	normal	0.411208263	0.481431744	normal	0.002703777	0.464067263	normal	--	--	--	"K01794|0|hsa:29940|DSE, DSEP, DSEPI, EDSMC2, SART-2, SART2; dermatan sulfate epimerase (EC:5.1.3.19); K01794 chondroitin-glucuronate 5-epimerase [EC:5.1.3.19] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	--	--	--	Dermatan-sulfate epimerase (Precursor) GN=DSE OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: dermatan-sulfate epimerase isoform X1 [Equus caballus] 
ENSG00000111832(RWDD1)	--	12.5515955	423	14.62087479	463	13.97758248	439	18.82696295	602	18.6355232	618	14.1688836	478	0.480986525	0.476815221	normal	0.748308923	0.394050607	normal	0.964704293	0.114121388	normal	0.105492274	0.336023368	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	RWD domain	RWD domain-containing protein 1 GN=RWDD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RWD domain-containing protein 1 isoform X1 [Ursus maritimus]
ENSG00000111834(RSPH4A)	--	0.200928738	12	0.149786895	6	0.148227736	5	0.178585473	10	0.131053726	7	0.06412075	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Radial spokehead-like protein	Radial spoke head protein 4 homolog A GN=RSPH4A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: radial spoke head protein 4 homolog A isoform X1 [Galeopterus variegatus]
ENSG00000111837(MAK)	--	0.266580951	17	0.423621997	27	0.23138987	13	0.109160134	7	0.14311933	8	0.031151887	2	--	--	--	0.438456027	-1.60287533	normal	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08829|0|mcf:101925297|uncharacterized LOC101925297; K08829 male germ cell-associated kinase [EC:2.7.11.22] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase MAK GN=MAK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase MAK isoform X1 [Ursus maritimus]
ENSG00000111843(TMEM14C)	--	90.11306	1324	98.90634	1470	95.30264	1413	128.38571	1930	100.15956	1476	113.38374	1680	0.286513447	0.512370418	normal	0.983392532	-0.015534043	normal	0.953325772	0.241171331	normal	0.1434328	0.252006375	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Transmembrane proteins 14C	Transmembrane protein 14C GN=TMEM14C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 14C [Oryctolagus cuniculus]
ENSG00000111845(PAK1IP1)	--	12.9485	408	14.6372	463	11.8356	369	14.7146	466	14.9341	469	13.1949	417	0.956732763	0.160363202	normal	0.970328285	-0.002841607	normal	0.954642389	0.167489052	normal	0.735547601	0.102952761	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14830|0|hsa:55003|PAK1IP1, MAK11, PIP1, WDR84, bA421M1.5, hPIP1; PAK1 interacting protein 1; K14830 protein MAK11 (A)"	--	[S]	Function unknown	"WD domain, G-beta repeat"	p21-activated protein kinase-interacting protein 1 GN=PAK1IP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: p21-activated protein kinase-interacting protein 1 [Myotis brandtii] 
ENSG00000111846(GCNT2)	--	6.444919471	505	8.247626	642	6.9956089	567	7.376616552	600	8.513334509	610	10.34106284	783	0.94286901	0.21723993	normal	0.969439416	-0.094961095	normal	0.531176461	0.456332089	normal	0.48846016	0.197099764	normal	--	--	Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; 	"K00742|0|ptr:462428|GCNT2; glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group); K00742 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.150] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Core-2/I-Branching enzyme	"N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C GN=GCNT2 OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase, isoform C-like [Vicugna pacos]"
ENSG00000111850(SMIM8)	--	3.956147403	126	5.079974419	146	5.043898411	151	3.105132124	101	2.973831093	96	3.343470462	94	0.921545633	-0.345188247	normal	0.533738725	-0.618329778	normal	0.351891651	-0.683351919	normal	0.119070018	-0.560890673	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4500)	Small integral membrane protein 8 GN=SMIM8 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: small integral membrane protein 8 isoform X5 [Canis lupus familiaris] 
ENSG00000111859(NEDD9)	--	9.800009776	889	16.22740633	1460	12.5389479	1120	16.72787381	1501	21.4020141	1927	21.09459437	1922	0.003177865	0.7238635	normal	0.811825876	0.378619307	normal	0.000763525	0.770015026	normal	0.0318767	0.604427768	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16832|0|pps:100989201|NEDD9; neural precursor cell expressed, developmentally down-regulated 9; K16832 enhancer of filamentation 1 (A)"	--	--	--	Domain of unknown function (DUF3513);; Serine rich protein interaction domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Enhancer of filamentation 1 p55 GN=NEDD9 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: enhancer of filamentation 1 isoform X1 [Equus caballus]
ENSG00000111860(CEP85L)	--	1.81502811	149	2.312385876	170	1.29308023	134	1.631397454	179	1.75163389	179	1.797261499	152	0.9446289	0.231633519	normal	0.965058252	0.052542762	normal	0.958005185	0.171726126	normal	0.737792794	0.149024422	normal	--	--	--	K16766|0|ggo:101140279|CEP85L; centrosomal protein of 85 kDa-like; K16766 centrosomal protein CEP85 (A)	--	--	--	--	Centrosomal protein of 85 kDa-like GN=CEP85L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centrosomal protein of 85 kDa-like [Ursus maritimus]
ENSG00000111863(ADTRP)	--	0.180146875	6	0.262359128	9	0.151077203	4	0.405195121	14	0.373850825	12	0.527220876	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[W]	Extracellular structures	FAR-17a/AIG1-like protein	Androgen-dependent TFPI-regulating protein GN=ADTRP OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: androgen-dependent TFPI-regulating protein isoform X1 [Mustela putorius furo] 
ENSG00000111875(ASF1A)	--	9.42916	228	9.51325	236	10.67084	279	17.04122	437	15.48115	366	14.78052	355	0.000448829	0.903298341	normal	0.184564573	0.608476068	normal	0.863157821	0.337636326	normal	0.004270491	0.618661497	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: chromatin assembly or disassembly (GO:0006333);; 	K10753|1.11396e-149|umr:103663452|ASF1A; anti-silencing function 1A histone chaperone; K10753 histone chaperone ASF1 (A)	--	[KB]	Transcription;; Chromatin structure and dynamics	ASF1 like histone chaperone	Histone chaperone ASF1A GN=ASF1A OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone chaperone ASF1A [Erinaceus europaeus]
ENSG00000111877(MCM9)	--	4.572694705	316	4.160040143	345	4.042483477	297	2.781743965	234	3.263664643	284	2.61136848	220	0.647369604	-0.461628935	normal	0.896688729	-0.300676732	normal	0.718462024	-0.438645724	normal	0.114653144	-0.397854768	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; Molecular Function: ATPase activity (GO:0016887);; 	"K10738|0|hsa:254394|MCM9, C6orf61, MCMDC1, dJ329L24.1, dJ329L24.3; minichromosome maintenance complex component 9 (EC:3.6.4.12); K10738 DNA helicase MCM9 [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; Magnesium chelatase, subunit ChlI;; AAA domain (dynein-related subfamily)"	DNA helicase MCM9 GN=MCM9 OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: DNA helicase MCM9 [Galeopterus variegatus]
ENSG00000111879(FAM184A)	--	0.581587988	52	0.448705801	44	0.468633945	39	0.31163288	15	0.214117923	20	0.037071683	3	0.006229397	-1.723828278	down	0.537267875	-1.101412681	normal	1.48E-05	-3.173176256	down	0.000511264	-1.852857827	down	--	--	--	--	--	--	--	--	Protein FAM184A GN=FAM184A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM184A isoform X1 [Tupaia chinensis]
ENSG00000111880(RNGTT)	--	7.9947001	600	10.44155609	727	9.219201	700	8.40931286	615	7.893210842	558	7.090793796	550	0.973782241	0.004779558	normal	0.722485862	-0.402158852	normal	0.819529741	-0.355346482	normal	0.217461879	-0.255917816	normal	[A]	RNA processing and modification	Molecular Function: mRNA guanylyltransferase activity (GO:0004484);; Biological Process: 7-methylguanosine mRNA capping (GO:0006370);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K13917|0|pps:100993736|RNGTT; RNA guanylyltransferase and 5'-phosphatase; K13917 mRNA-capping enzyme [EC:2.7.7.50 3.6.1.-] (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"mRNA capping enzyme, catalytic domain;; mRNA capping enzyme, C-terminal domain;; Dual specificity phosphatase, catalytic domain"	mRNA guanylyltransferase GN=RNGTT OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: mRNA-capping enzyme isoform 1 [Equus caballus] 
ENSG00000111885(MAN1A1)	--	8.700772559	548	5.887930615	424	6.81992	442	2.887051429	227	3.83513216	256	3.756576124	283	1.84E-09	-1.296476307	down	0.014870058	-0.745885083	normal	0.070810772	-0.648738382	normal	3.02E-06	-0.9049903	normal	--	--	"Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: membrane (GO:0016020);; "	"K01230|0|pon:100434522|MAN1A1; mannosidase, alpha, class 1A, member 1; K01230 mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 47	"Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA GN=MAN1A1 OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IA [Galeopterus variegatus]"
ENSG00000111886(GABRR2)	--	0	0	0.096881	3	0.0953631	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05190|0|hsa:2570|GABRR2; gamma-aminobutyric acid (GABA) A receptor, rho 2; K05190 gamma-aminobutyric acid receptor subunit rho (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Gamma-aminobutyric acid receptor subunit rho-2 (Precursor) GN=GABRR2 OS=Homo sapiens (Human) PE=2 SV=5	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit rho-2 [Pteropus alecto]
ENSG00000111897(SERINC1)	--	48.377	2281	53.4729	2560	45.2565	2107	50.7449	2421	46.3551	2175	56.2728	2643	0.987576295	0.055068364	normal	0.95820626	-0.256390436	normal	0.917319228	0.318490152	normal	0.890265455	0.037948052	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Serine incorporator (Serinc)	Serine incorporator 1 GN=SERINC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: serine incorporator 1 [Galeopterus variegatus]
ENSG00000111906(HDDC2)	--	37.693765	644	34.28816039	602	36.250884	648	36.330369	637	36.75248	637	35.157135	626	0.973456076	-0.04648806	normal	0.971838638	0.059956899	normal	0.972968027	-0.057984908	normal	0.967377887	-0.016585398	normal	[R]	General function prediction only	--	"K07023|1.52134e-150|hsa:51020|HDDC2, C6orf74, NS5ATP2, dJ167O5.2; HD domain containing 2; K07023 putative hydrolases of HD superfamily (A)"	--	[R]	General function prediction only	HD domain;; HD domain	HD domain-containing protein 2 GN=HDDC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: HD domain-containing protein 2 [Trichechus manatus latirostris]
ENSG00000111907(TPD52L1)	--	21.51917454	514	18.45313005	433	18.69827536	433	23.2223099	550	32.08657926	738	25.49112269	582	0.970357502	0.06663842	normal	0.005188011	0.745809777	normal	0.684960642	0.417099791	normal	0.068105232	0.417358998	normal	--	--	--	--	--	[R]	General function prediction only	Tumour protein D52 family	Tumor protein D53 GN=TPD52L1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tumor protein D53 isoform X1 [Galeopterus variegatus]
ENSG00000111911(HINT3)	--	10.6029	507	10.2714	499	8.73979	416	11.4004	558	10.7369	515	13.9083	668	0.966899667	0.107137567	normal	0.970940721	0.024034361	normal	0.024302242	0.673024813	normal	0.21874888	0.270980308	normal	[FGR]	Nucleotide transport and metabolism;; Carbohydrate transport and metabolism;; General function prediction only	--	--	--	[R]	General function prediction only	Scavenger mRNA decapping enzyme C-term binding;; HIT domain	Histidine triad nucleotide-binding protein 3 GN=HINT3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: histidine triad nucleotide-binding protein 3 [Pteropus alecto] 
ENSG00000111912(NCOA7)	--	49.855595	2494	36.94924573	1942	37.19766865	2040	29.46517888	1652	38.50073608	1988	38.05813243	2204	0.033053942	-0.624603567	normal	0.986326721	0.012338502	normal	0.98448665	0.103190019	normal	0.555175939	-0.168544373	normal	--	--	--	--	--	[L]	"Replication, recombination and repair"	TLD;; LysM domain	Nuclear receptor coactivator 7 GN=NCOA7 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: nuclear receptor coactivator 7 isoform X1 [Galeopterus variegatus] 
ENSG00000111913(FAM65B)	--	0	0	0	0	0	0	0.009257058	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM65B GN=FAM65B OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: protein FAM65B isoformX1 [Equus caballus]
ENSG00000111961(SASH1)	--	2.693964901	412	3.278750645	512	2.847166745	425	3.00928113	458	2.254320806	341	3.176533596	492	0.963156798	0.121441347	normal	0.124435375	-0.605590756	normal	0.946563399	0.202234661	normal	0.824510054	-0.084693401	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Lymphocyte signaling adaptor protein;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Variant SH3 domain	SAM and SH3 domain-containing protein 1 GN=SASH1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SAM and SH3 domain-containing protein 1 isoform X1 [Loxodonta africana]
ENSG00000111962(UST)	--	9.046944499	401	9.550657363	386	8.496374491	389	7.464629136	312	9.224133976	353	10.06274097	487	0.774840076	-0.391184103	normal	0.95678701	-0.149745473	normal	0.878372396	0.314764353	normal	0.911558094	-0.049612815	normal	--	--	Molecular Function: galactosylceramide sulfotransferase activity (GO:0001733);; Cellular Component: Golgi apparatus (GO:0005794);; Molecular Function: sulfotransferase activity (GO:0008146);; Biological Process: glycolipid biosynthetic process (GO:0009247);; Cellular Component: integral component of membrane (GO:0016021);; 	K03193|0|pps:100993550|UST; uronyl-2-sulfotransferase; K03193 dermatan/chondrotin sulfate uronyl 2-O-sulfotransferase UST [EC:2.8.2.-] (A)	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase family;; Galactose-3-O-sulfotransferase	Uronyl 2-sulfotransferase GN=UST OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: uronyl 2-sulfotransferase [Tupaia chinensis]
ENSG00000111981(ULBP1)	--	3.661439498	239	3.43866	220	2.39814316	153	0.558109593	36	0.719816428	46	2.272137493	149	0	-2.709993367	down	2.00E-15	-2.242026558	down	0.967140813	-0.046049513	normal	0.016118959	-1.423297307	normal	--	--	--	"K07986|4.41126e-167|hsa:80329|ULBP1, RAET1I; UL16 binding protein 1; K07986 UL16 binding protein (A)"	Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2"	NKG2D ligand 1 (Precursor) GN=ULBP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: NKG2D ligand 1-like [Equus caballus]
ENSG00000112029(FBXO5)	--	13.38764	482	11.13527	401	15.08203	525	13.96192	505	11.24304	407	9.34989	346	0.971015131	0.036304918	normal	0.968992799	3.20E-16	normal	0.108404991	-0.607664702	normal	0.566069386	-0.184526335	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10292|0|pps:100977978|FBXO5; F-box protein 5; K10292 F-box protein 5 (A)	Oocyte meiosis (ko04114)	--	--	F-box domain	F-box only protein 5 GN=FBXO5 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: F-box only protein 5 [Oryctolagus cuniculus]
ENSG00000112031(MTRF1L)	--	10.08876048	706	9.821283215	695	10.60615388	737	9.487957794	689	9.787696122	714	8.96115322	662	0.973493936	-0.065851389	normal	0.974784775	0.017447084	normal	0.961835371	-0.162772246	normal	0.800513651	-0.07130176	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: translation release factor activity (GO:0003747);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: translational termination (GO:0006415);; Molecular Function: translation release factor activity, codon specific (GO:0016149);; "	K02835|0|pps:100977203|MTRF1L; mitochondrial translational release factor 1-like; K02835 peptide chain release factor 1 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	RF-1 domain;; PCRF domain	"Peptide chain release factor 1-like, mitochondrial (Precursor) GN=MTRF1L OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: peptide chain release factor 1-like, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000112033(PPARD)	--	4.800411131	366	3.516554185	269	4.973759095	379	4.13925423	309	4.417371433	330	3.689558735	284	0.913998553	-0.273816241	normal	0.916153744	0.27205042	normal	0.715848556	-0.422643212	normal	0.616984096	-0.156647862	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K04504|0|hsa:5467|PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB; peroxisome proliferator-activated receptor delta; K04504 peroxisome proliferator-activated receptor delta (A)"	PPAR signaling pathway (ko03320);; Wnt signaling pathway (ko04310);; Pathways in cancer (ko05200);; Acute myeloid leukemia (ko05221)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Peroxisome proliferator-activated receptor delta GN=PPARD OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: peroxisome proliferator-activated receptor delta isoform 1 [Ceratotherium simum simum]
ENSG00000112039(FANCE)	--	2.93277638	119	1.907134595	89	2.211166469	102	2.313154337	94	1.95250103	70	1.502774	66	0.917062291	-0.365734059	normal	0.935712428	-0.360943512	normal	0.70722041	-0.62471803	normal	0.30674643	-0.452973958	normal	--	--	--	"K10892|0|hsa:2178|FANCE, FACE, FAE; Fanconi anemia, complementation group E; K10892 fanconi anemia group E protein (A)"	Fanconi anemia pathway (ko03460)	--	--	Fanconi Anaemia group E protein FANCE	Fanconi anemia group E protein GN=FANCE OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: Fanconi anemia group E protein [Lipotes vexillifer]
ENSG00000112041(TULP1)	--	0	0	0	0	0	0	0.042752352	2	0.021087625	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Tub family	Tubby-related protein 1 GN=TULP1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: tubby-related protein 1 [Odobenus rosmarus divergens]
ENSG00000112053(SLC26A8)	--	0	0	0	0	0	0	0.017103065	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14705|0|hsa:116369|SLC26A8, SPGF3, TAT1; solute carrier family 26 (anion exchanger), member 8; K14705 solute carrier family 26 (testis anion transporter), member 8 (A)"	--	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain	Testis anion transporter 1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: testis anion transporter 1 [Galeopterus variegatus]
ENSG00000112062(MAPK14)	--	14.18213878	898	15.9828804	1035	15.10424005	950	19.89005929	1281	19.09328912	1179	18.03281469	1115	0.411734867	0.480958702	normal	0.967848464	0.166278635	normal	0.951610666	0.222425698	normal	0.096058356	0.288693552	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K04441|0|tup:102495693|MAPK14; mitogen-activated protein kinase 14; K04441 p38 MAP kinase [EC:2.7.11.24] (A)	MAPK signaling pathway (ko04010);; Rap1 signaling pathway (ko04015);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Prolactin signaling pathway (ko04917);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Mitogen-activated protein kinase 14 GN=MAPK14 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 14 isoform X1 [Oryctolagus cuniculus]
ENSG00000112077(RHAG)	--	0.102262	3	0	0	0	0	0	0	0.0664276	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; 	"K06580|0|hsa:6005|RHAG, CD241, RH2, RH50A, Rh50, Rh50GP, SLC42A1; Rh-associated glycoprotein; K06580 ammonium transporter Rh (A)"	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Ammonium Transporter Family	Ammonium transporter Rh type A GN=RHAG OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: ammonium transporter Rh type A [Myotis brandtii]
ENSG00000112078(KCTD20)	--	9.339639005	922	9.839046831	918	9.738272079	920	12.86788301	1161	11.29016766	1043	10.5757647	1022	0.901861954	0.301248891	normal	0.966568863	0.162495277	normal	0.970137096	0.143174601	normal	0.294294285	0.203477043	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD20 GN=KCTD20 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	BTB/POZ domain-containing protein KCTD20 [Tupaia chinensis]
ENSG00000112079(STK38)	--	14.4195	951	16.84848	1103	17.11383	1109	19.02385	1255	16.62761	1090	24.01913	1583	0.802178014	0.368817758	normal	0.979639407	-0.038478144	normal	0.314566041	0.504531651	normal	0.312120945	0.292065973	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08790|0|umr:103665445|STK38; serine/threonine kinase 38; K08790 serine/threonine kinase 38 [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Protein kinase C terminal domain;; Kinase-like	Serine/threonine-protein kinase 38 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	Serine/threonine-protein kinase 38 [Myotis davidii]
ENSG00000112081(SRSF3)	--	123.0552115	4323	131.8662581	4714	132.7016301	4658	142.541829	5137	147.0817904	5235	115.8948495	4189	0.98170685	0.217989836	normal	0.990420436	0.129771703	normal	0.98759377	-0.161340933	normal	0.789634621	0.066774074	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12892|4.86072e-56|xtr:448605|srsf3, sfrs3, srp20; serine/arginine-rich splicing factor 3; K12892 splicing factor, arginine/serine-rich 3 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Serine/arginine-rich splicing factor 3 GN=SRSF3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	Serine/arginine-rich splicing factor 3 [Myotis brandtii]
ENSG00000112096(SOD2)	--	66.69754083	3500	82.281622	4614	56.86037748	2897	166.2775552	9169	143.106313	8267	313.0304139	18422	1.14E-14	1.3581951	up	0.000242007	0.819715902	normal	0	2.659874679	up	0.04032924	1.683669403	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: superoxide dismutase activity (GO:0004784);; Biological Process: superoxide metabolic process (GO:0006801);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K04564|4.97008e-165|hsa:6648|SOD2, IPOB, MNSOD, MVCD6; superoxide dismutase 2, mitochondrial (EC:1.15.1.1); K04564 superoxide dismutase, Fe-Mn family [EC:1.15.1.1] (A)"	FoxO signaling pathway (ko04068);; Peroxisome (ko04146);; Huntington's disease (ko05016)	[P]	Inorganic ion transport and metabolism	"Iron/manganese superoxide dismutases, C-terminal domain;; Iron/manganese superoxide dismutases, alpha-hairpin domain"	"Superoxide dismutase [Mn], mitochondrial (Precursor) GN=SOD2 OS=Homo sapiens (Human) PE=1 SV=2"	P	Inorganic ion transport and metabolism	"PREDICTED: superoxide dismutase [Mn], mitochondrial [Equus przewalskii]"
ENSG00000112110(MRPL18)	--	49.81748838	763	51.31470127	806	58.33424	906	54.99638486	866	50.93237276	780	48.55604227	754	0.966018188	0.151565102	normal	0.97437774	-0.06860142	normal	0.920340811	-0.272738193	normal	0.813067828	-0.065772551	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02881|5.20758e-130|ptr:739895|MRPL18; mitochondrial ribosomal protein L18; K02881 large subunit ribosomal protein L18 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L18p/L5e family	"39S ribosomal protein L18, mitochondrial (Precursor) GN=MRPL18 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L18, mitochondrial isoformX2 [Canis lupus familiaris]"
ENSG00000112118(MCM3)	--	34.9953788	2482	35.5457782	2560	38.12489381	2742	33.98745291	2404	36.89829702	2586	26.74639926	1888	0.987212103	-0.07685014	normal	0.988732196	-0.00684407	normal	0.177593835	-0.546295975	normal	0.295567705	-0.200153334	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; 	K02541|0|pps:100980176|MCM3; minichromosome maintenance complex component 3; K02541 DNA replication licensing factor MCM3 [EC:3.6.4.12] (A)	DNA replication (ko03030);; Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; MCM N-terminal domain;; Magnesium chelatase, subunit ChlI"	DNA replication licensing factor MCM3 GN=MCM3 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA replication licensing factor MCM3 [Equus caballus] 
ENSG00000112130(RNF8)	--	5.7771092	348	7.487738271	353	8.397988848	408	7.540815203	445	6.879956811	439	6.586284262	372	0.871466813	0.322623552	normal	0.89983119	0.292002548	normal	0.959570779	-0.141010383	normal	0.57988801	0.158171484	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K10667|0|hsa:9025|RNF8, hRNF8; ring finger protein 8, E3 ubiquitin protein ligase (EC:6.3.2.-); K10667 E3 ubiquitin-protein ligase RNF8 [EC:6.3.2.19] (A)"	--	[T]	Signal transduction mechanisms	"FHA domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	E3 ubiquitin-protein ligase RNF8 GN=RNF8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1-like isoform X11 [Mustela putorius furo] 
ENSG00000112137(PHACTR1)	--	0.463796868	30	0.745280506	51	0.329582023	17	0.53365744	45	0.543549239	46	0.99419112	84	0.950400606	0.53176832	normal	0.975151462	-0.165131417	normal	3.64E-07	2.199769078	up	0.313199848	0.815778814	normal	--	--	--	--	--	[R]	General function prediction only	RPEL repeat	Phosphatase and actin regulator 1 GN=PHACTR1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: phosphatase and actin regulator 1 [Orycteropus afer afer]
ENSG00000112139(MDGA1)	--	1.45929589	102	0.805060607	94	0.769801681	95	2.798097223	419	3.313166451	509	3.264826231	420	0	1.991544622	up	0	2.396962215	up	0	2.118578533	up	6.72E-26	2.190612761	up	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; MAM domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	MAM domain-containing glycosylphosphatidylinositol anchor protein 1 (Precursor) GN=MDGA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: MAM domain-containing glycosylphosphatidylinositol anchor protein 1 isoform X1 [Mustela putorius furo] 
ENSG00000112144(ICK)	--	1.53072125	161	2.036959768	209	1.633379243	169	1.871730027	197	2.134875632	224	2.158922348	228	0.934768273	0.258073329	normal	0.963411477	0.078023843	normal	0.797882088	0.420468328	normal	0.484534218	0.246997439	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08828|0|hsa:22858|ICK, ECO, LCK2, MRK; intestinal cell (MAK-like) kinase (EC:2.7.11.22); K08828 intestinal cell (MAK-like) kinase [EC:2.7.11.22] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase ICK GN=ICK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase ICK [Equus caballus]
ENSG00000112146(FBXO9)	--	16.6663015	716	14.28814	675	11.496847	609	15.1748949	696	14.6669872	682	13.5079518	656	0.973289508	-0.071548809	normal	0.974450946	-0.006527771	normal	0.96989058	0.098725886	normal	0.997845419	0.00273996	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10295|0|hsa:26268|FBXO9, FBX9, NY-REN-57, VCIA1, dJ341E18.2; F-box protein 9; K10295 F-box protein 9 (A)"	--	[R]	General function prediction only	F-box-like;; F-box domain	F-box only protein 9 GN=FBXO9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: F-box only protein 9 [Equus przewalskii]
ENSG00000112149(CD83)	--	1.478245669	62	1.654678606	71	1.580118119	67	0.592887445	25	0.92824864	39	0.758517945	32	0.058266212	-1.289175288	normal	0.505399597	-0.860669154	normal	0.249343239	-1.039685426	normal	0.020532071	-1.079261706	normal	--	--	--	K06510|1.2963e-145|pps:100986923|CD83; CD83 molecule; K06510 CD83 antigen (A)	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	CD83 antigen (Precursor) GN=CD83 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CD83 antigen [Oryctolagus cuniculus]
ENSG00000112159(MDN1)	--	4.236966602	1727	4.485407993	1843	4.833208404	1966	4.2379137	1722	4.228947095	1705	4.4601558	1805	0.985115702	-0.034984035	normal	0.979569123	-0.133596878	normal	0.980887819	-0.131450363	normal	0.641690918	-0.102374904	normal	--	--	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K14572|0|hsa:23195|MDN1; MDN1, midasin homolog (yeast); K14572 midasin (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	"AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA);; ATPase family associated with various cellular activities (AAA);; AAA ATPase domain;; AAA domain;; Sigma-54 interaction domain;; AAA domain;; AAA domain;; ABC transporter;; AAA domain;; Miro-like protein;; Sigma-54 interaction domain;; Uncharacterised P-loop hydrolase UPF0079;; Protein of unknown function, DUF258;; AAA domain;; NACHT domain;; Ethanolamine utilisation - propanediol utilisation;; Protein of unknown function (DUF815);; AAA domain;; Part of AAA domain;; Type II/IV secretion system protein;; RNA helicase;; AAA domain;; P-loop containing region of AAA domain;; IstB-like ATP binding protein;; Magnesium chelatase, subunit ChlI;; Molybdopterin guanine dinucleotide synthesis protein B;; Holliday junction DNA helicase ruvB N-terminus;; Archaeal ATPase;; 50S ribosome-binding GTPase;; Signal recognition particle receptor beta subunit;; Chloramphenicol phosphotransferase-like protein;; Rad17 cell cycle checkpoint protein"	Midasin GN=MDN1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: midasin [Ceratotherium simum simum]
ENSG00000112167(SAYSD1)	--	4.559994	113	5.059852	130	4.429534	109	5.076361	116	6.01661	130	5.350632	133	0.969778476	0.006877477	normal	0.967267234	-0.021180173	normal	0.941773445	0.275343076	normal	0.886719891	0.085649572	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved domain (SAYSvFN)	SAYSvFN domain-containing protein 1 GN=SAYSD1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SAYSvFN domain-containing protein 1 [Leptonychotes weddellii]
ENSG00000112175(BMP5)	--	0.0312978	2	0.0472215	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04663|0|ptr:462787|BMP5; bone morphogenetic protein 5; K04663 bone morphogenetic protein 5 (A)	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Bone morphogenetic protein 5 (Precursor) GN=BMP5 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein 5 [Oryctolagus cuniculus]
ENSG00000112182(BACH2)	--	0.094083264	3	0	0	0.005889301	0	0	0	0.023611307	2	0.024092172	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09042|0|pps:100973680|BACH2; BTB and CNC homology 1, basic leucine zipper transcription factor 2; K09042 transcription regulator BACH (A)"	--	[K]	Transcription	BTB/POZ domain;; bZIP Maf transcription factor;; bZIP transcription factor;; Basic region leucine zipper	Transcription regulator protein BACH2 GN=BACH2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription regulator protein BACH2-like [Elephantulus edwardii]
ENSG00000112183(RBM24)	--	11.18471423	492	12.2997793	468	13.89510154	636	10.90910449	488	9.540171614	432	10.10714883	466	0.970731495	-0.042476241	normal	0.960605098	-0.136444707	normal	0.550867529	-0.455717062	normal	0.353859722	-0.224377614	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 24 GN=RBM24 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RNA-binding protein 24 [Odobenus rosmarus divergens]
ENSG00000112186(CAP2)	--	13.42068076	722	13.31439356	750	13.8093624	761	14.26914817	812	14.0662823	762	14.48170022	830	0.967330176	0.138370869	normal	0.975748588	0.001470902	normal	0.970875259	0.116701317	normal	0.74601295	0.08535328	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	"K17261|0|hsa:10486|CAP2; CAP, adenylate cyclase-associated protein, 2 (yeast); K17261 adenylyl cyclase-associated protein (A)"	--	[ZT]	Cytoskeleton;; Signal transduction mechanisms	Adenylate cyclase associated (CAP) N terminal;; Adenylate cyclase associated (CAP) C terminal;; Tubulin binding cofactor C	Adenylyl cyclase-associated protein 2 GN=CAP2 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: adenylyl cyclase-associated protein 2 [Tupaia chinensis]
ENSG00000112200(ZNF451)	--	10.3650046	818	11.22171765	860	10.88817844	810	9.201178002	756	9.4366	739	10.66716066	791	0.966785346	-0.1442649	normal	0.939030533	-0.239733572	normal	0.976312322	-0.042455441	normal	0.531851901	-0.14330105	normal	--	--	--	--	--	[R]	General function prediction only	C2H2-type zinc finger	Zinc finger protein 451 GN=ZNF451 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 451 isoform X1 [Pteropus alecto]
ENSG00000112208(BAG2)	--	6.83238	660	7.228479	695	8.4163723	793	9.75995	953	8.00524	776	7.561585	734	0.350571301	0.498207974	normal	0.966455033	0.13733421	normal	0.969988764	-0.119595115	normal	0.430925855	0.175660291	normal	--	--	--	K09556|1.27796e-151|ptr:462797|BAG2; BCL2-associated athanogene 2; K09556 BCL2-associated athanogene 2 (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	BAG domain	BAG family molecular chaperone regulator 2 GN=BAG2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: BAG family molecular chaperone regulator 2 [Oryctolagus cuniculus]
ENSG00000112210(RAB23)	--	7.934134461	432	7.573478387	440	7.910533639	421	10.57464201	605	9.941384107	570	8.444976109	472	0.564233339	0.453702446	normal	0.832131103	0.350969411	normal	0.957926612	0.156145202	normal	0.121239561	0.327155686	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K06234|9.32337e-176|hsa:51715|RAB23, HSPC137; RAB23, member RAS oncogene family; K06234 Ras-related protein Rab-23 (A)"	Hedgehog signaling pathway (ko04340)	[T]	Signal transduction mechanisms	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region;; Conserved hypothetical ATP binding protein	Ras-related protein Rab-23 (Precursor) GN=RAB23 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-23-like [Panthera tigris altaica]
ENSG00000112218(GPR63)	--	0.745094018	62	0.846319	70	1.035293	84	0.27144124	22	0.3504502	29	0.098880281	8	0.013958375	-1.462140035	normal	0.041252788	-1.249469847	normal	9.50E-12	-3.175826545	down	2.30E-05	-1.894826854	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04321|0|hsa:81491|GPR63, PSP24(beta), PSP24B; G protein-coupled receptor 63; K04321 G protein-coupled receptor 63 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Probable G-protein coupled receptor 63 GN=GPR63 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 63 [Oryctolagus cuniculus]
ENSG00000112232(KHDRBS2)	--	0	0	0	0	0	0	0	0	0	0	0.0501443	2	--	--	--	--	--	--	--	--	--	--	--	--	[A]	RNA processing and modification	Molecular Function: RNA binding (GO:0003723);; 	"K17843|0|ptr:462799|KHDRBS2; KH domain containing, RNA binding, signal transduction associated 2; K17843 KH domain-containing, RNA-binding, signal transduction-associated protein 2 (A)"	--	[A]	RNA processing and modification	KH domain;; KH domain	"KH domain-containing, RNA-binding, signal transduction-associated protein 2 GN=KHDRBS2 OS=Homo sapiens (Human) PE=1 SV=1"	A	RNA processing and modification	"PREDICTED: KH domain-containing, RNA-binding, signal transduction-associated protein 2 [Orycteropus afer afer]"
ENSG00000112234(FBXL4)	--	6.196568518	436	5.823315171	421	6.424110287	490	5.391641153	378	4.677022169	340	5.433355202	401	0.932989405	-0.235880471	normal	0.867033771	-0.328396582	normal	0.895352043	-0.296457768	normal	0.218761422	-0.288349868	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10270|0|hsa:26235|FBXL4, FBL4, FBL5, MTDPS13; F-box and leucine-rich repeat protein 4; K10270 F-box and leucine-rich repeat protein 4 (A)"	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; F-box domain;; Leucine rich repeat;; F-box-like;; Leucine Rich Repeat	F-box/LRR-repeat protein 4 GN=FBXL4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 4 isoform X1 [Equus caballus] 
ENSG00000112237(CCNC)	--	26.59873135	763	26.42349681	785	27.71159055	737	33.66603582	871	27.78130332	803	21.881072	635	0.964527509	0.159855972	normal	0.976284102	0.01125933	normal	0.943929107	-0.222706663	normal	0.988440292	-0.007108412	normal	--	--	--	K15161|0|shr:100931061|CCNC; cyclin C; K15161 cyclin C (A)	--	[K]	Transcription	"Cyclin, N-terminal domain"	Cyclin-C GN=CCNC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cyclin-C [Sarcophilus harrisii]
ENSG00000112238(PRDM13)	--	1.402624518	76	0.970827998	54	0.697778847	39	0.347284231	19	0.389850735	21	0.452691176	25	1.83E-05	-1.946060194	down	0.094073004	-1.322509577	normal	0.944007703	-0.619598597	normal	0.007233673	-1.399617067	down	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; BED zinc finger"	PR domain zinc finger protein 13 GN=PRDM13 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: PR domain zinc finger protein 13 [Physeter catodon]
ENSG00000112242(E2F3)	--	11.026057	837	11.511044	881	10.58915	804	10.12245	777	11.115607	842	9.854907	756	0.968145547	-0.137882501	normal	0.974225282	-0.086596274	normal	0.972668547	-0.096912688	normal	0.659030741	-0.107986982	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K06620|0|ptr:471865|E2F3; E2F transcription factor 3; K06620 transcription factor E2F3 (A)	Cell cycle (ko04110);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[K]	Transcription	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F3 GN=E2F3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor E2F3 isoform 1 [Ceratotherium simum simum]
ENSG00000112245(PTP4A1)	--	165.0017	6845	181.91429	7533	175.00913	7217	179.86136	7574	140.74862	6031	241.45438	10258	0.993545038	0.115148039	normal	0.944766405	-0.342176901	normal	0.553349004	0.49889875	normal	0.799507975	0.123730693	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18041|1.31491e-127|umr:103657372|PTP4A1; protein tyrosine phosphatase type IVA, member 1; K18041 protein tyrosine phosphatase type IVA [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain"	Protein tyrosine phosphatase type IVA 1 (Precursor) GN=PTP4A1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein tyrosine phosphatase type IVA 1 isoform 1 [Equus caballus] 
ENSG00000112249(ASCC3)	--	12.9559415	1720	14.95579383	2034	15.543027	2146	16.49500245	2227	13.36083999	1877	15.598196	2042	0.880599002	0.341591948	normal	0.980468249	-0.137211351	normal	0.985605906	-0.079900923	normal	0.891108288	0.037621012	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K18663|0|pps:100985039|ASCC3; activating signal cointegrator 1 complex subunit 3; K18663 activating signal cointegrator complex subunit 3 [EC:3.6.4.12] (A)	--	[A]	RNA processing and modification	"Sec63 Brl domain;; DEAD/DEAH box helicase;; Type III restriction enzyme, res subunit;; Helicase conserved C-terminal domain;; AAA domain;; PhoH-like protein;; Type II/IV secretion system protein"	Activating signal cointegrator 1 complex subunit 3 GN=ASCC3 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: activating signal cointegrator 1 complex subunit 3 [Oryctolagus cuniculus]
ENSG00000112276(BVES)	--	2.728221586	218	2.935622394	212	2.524567591	224	2.414633483	217	2.607580384	221	2.343169971	212	0.96644386	-0.037202554	normal	0.965267769	0.03828804	normal	0.963981985	-0.087121222	normal	0.958188686	-0.030011407	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Popeye protein conserved region	Blood vessel epicardial substance GN=BVES OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: blood vessel epicardial substance isoform X1 [Felis catus] 
ENSG00000112282(MED23)	--	5.407532381	448	5.41899602	446	5.283132122	430	6.094831604	487	6.22818433	509	6.72535532	550	0.967343009	0.089297008	normal	0.955141767	0.16865977	normal	0.838173067	0.345725842	normal	0.409208517	0.202748966	normal	--	--	--	K15166|0|pps:100972789|MED23; mediator complex subunit 23; K15166 mediator of RNA polymerase II transcription subunit 23 (A)	--	[K]	Transcription	Mediator complex subunit 23	Mediator of RNA polymerase II transcription subunit 23 GN=MED23 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 23 isoform X1 [Panthera tigris altaica] 
ENSG00000112290(WASF1)	--	7.1195093	318	6.80287308	322	9.403063941	348	7.84797972	358	7.46308537	331	9.76154656	368	0.958862647	0.139465254	normal	0.967216772	0.01825939	normal	0.966610722	0.072022626	normal	0.834721539	0.076398992	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	"K05753|0|ssc:100154562|WASF1; WAS protein family, member 1; K05753 WAS protein family, member 1 (A)"	Adherens junction (ko04520);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132);; Choline metabolism in cancer (ko05231)	[Z]	Cytoskeleton	WH2 motif	Wiskott-Aldrich syndrome protein family member 1 GN=WASF1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	"PREDICTED: wiskott-Aldrich syndrome protein family member 1, partial [Sus scrofa]"
ENSG00000112293(GPLD1)	--	1.0471579	71	1.188123	80	1.09799	75	0.579947673	37	0.856736	58	0.611314	42	0.357006803	-0.942373133	normal	0.90471601	-0.47478554	normal	0.543177132	-0.822333997	normal	0.11064404	-0.742832331	normal	--	--	--	"K01127|0|hsa:2822|GPLD1, GPIPLD, GPIPLDM, PIGPLD, PIGPLD1, PLD; glycosylphosphatidylinositol specific phospholipase D1 (EC:3.1.4.50); K01127 glycosylphosphatidylinositol phospholipase D [EC:3.1.4.50] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[W]	Extracellular structures	"FG-GAP repeat;; Zinc dependent phospholipase C;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Phosphatidylinositol-glycan-specific phospholipase D (Precursor) GN=GPLD1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: phosphatidylinositol-glycan-specific phospholipase D [Galeopterus variegatus]
ENSG00000112294(ALDH5A1)	--	6.491121407	523	6.95453927	467	7.26811006	512	6.260136183	536	7.1559054	629	6.512455729	547	0.972307679	0.004576511	normal	0.715571201	0.407071317	normal	0.968952084	0.086857338	normal	0.503126917	0.167832767	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00139|0|hsa:7915|ALDH5A1, SSADH, SSDH; aldehyde dehydrogenase 5 family, member A1 (EC:1.2.1.24); K00139 succinate-semialdehyde dehydrogenase [EC:1.2.1.24] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Butanoate metabolism (ko00650)"	[C]	Energy production and conversion	Aldehyde dehydrogenase family	"Succinate-semialdehyde dehydrogenase, mitochondrial (Precursor) GN=ALDH5A1 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: succinate-semialdehyde dehydrogenase, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000112297(AIM1)	--	0.889889407	113	0.4356411	49	0.718400242	96	0.691134849	96	0.9489652	128	0.7195143	92	0.949930115	-0.262175993	normal	0.000267381	1.337401958	up	0.970446856	-0.068588179	normal	0.664584708	0.271881952	normal	--	--	--	--	--	--	--	Beta/Gamma crystallin;; Ricin-type beta-trefoil lectin domain	Absent in melanoma 1 protein GN=AIM1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: absent in melanoma 1 protein [Galeopterus variegatus]
ENSG00000112299(VNN1)	--	0.347245347	18	0.474815782	19	0.194434763	9	2.200906203	108	1.992010002	101	2.362407104	116	2.32E-10	2.457765822	up	6.67E-09	2.30075793	up	0	3.475021368	up	5.13E-12	2.798602443	up	[R]	General function prediction only	"Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; "	"K08069|0|hsa:8876|VNN1, HDLCQ8, Tiff66; vanin 1 (EC:3.5.1.92); K08069 pantetheine hydrolase [EC:3.5.1.92] (A)"	Pantothenate and CoA biosynthesis (ko00770)	[E]	Amino acid transport and metabolism	Carbon-nitrogen hydrolase	Pantetheinase (Precursor) GN=VNN1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: pantetheinase [Ceratotherium simum simum]
ENSG00000112303(VNN2)	--	0.059145348	2	0.059002306	2	0	0	0.624745555	18	0.48054207	12	0.410175052	12	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; "	K08069|0|ggo:101126426|VNN2; LOW QUALITY PROTEIN: vascular non-inflammatory molecule 2; K08069 pantetheine hydrolase [EC:3.5.1.92] (A)	Pantothenate and CoA biosynthesis (ko00770)	[E]	Amino acid transport and metabolism	Carbon-nitrogen hydrolase	Vascular non-inflammatory molecule 2 (Precursor) GN=VNN2 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: vascular non-inflammatory molecule 2 [Oryctolagus cuniculus] 
ENSG00000112304(ACOT13)	--	9.755241	739	10.94012	833	9.800073	730	10.16946	775	9.131656	689	12.307247	935	0.975711937	0.037713117	normal	0.901898796	-0.294649885	normal	0.83455535	0.348139648	normal	0.909622586	0.038712401	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	--	"K17362|2.62196e-97|pon:100173179|ACOT13, THEM2; acyl-CoA thioesterase 13; K17362 acyl-coenzyme A thioesterase 13 [EC:3.1.2.-] (A)"	--	[R]	General function prediction only	Thioesterase superfamily	"Acyl-coenzyme A thioesterase 13, N-terminally processed GN=ACOT13 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	PREDICTED: acyl-coenzyme A thioesterase 13 [Echinops telfairi]
ENSG00000112305(SMAP1)	--	9.598340832	341	8.988860145	302	10.57127001	350	9.0601849	273	9.849388607	284	8.523260782	276	0.849890298	-0.349936619	normal	0.961253638	-0.109518522	normal	0.85024981	-0.349274483	normal	0.314381278	-0.27443292	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; 	"K12486|0|hsa:60682|SMAP1, SMAP-1; small ArfGAP 1; K12486 stromal membrane-associated protein (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf	Stromal membrane-associated protein 1 GN=SMAP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: stromal membrane-associated protein 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000112306(RPS12)	--	890.905	6404	838.935	6204	868.554	6481	1185.87	8934	1054.4	7590	1023.05	7561	0.751982068	0.44940903	normal	0.977207952	0.269415182	normal	0.986908529	0.2140229	normal	0.070651552	0.313701783	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02951|6.45686e-90|umr:103663389|40S ribosomal protein S12; K02951 small subunit ribosomal protein S12e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	40S ribosomal protein S12 GN=RPS12 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S12 [Erinaceus europaeus]
ENSG00000112308(C6orf62)	--	35.9504328	2246	40.07733	2485	37.52686292	2333	45.47588378	2835	40.08066924	2502	40.870775	2562	0.931780511	0.304972511	normal	0.988453505	-0.011583595	normal	0.984364885	0.12671432	normal	0.491838849	0.139600111	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4566)	Uncharacterized protein C6orf62 GN=C6orf62 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C6orf62 homolog isoform X1 [Oryctolagus cuniculus]
ENSG00000112309(B3GAT2)	--	2.516125	212	2.6304895	219	2.955375	246	2.453609	210	2.206938	186	2.04284	171	0.966233356	-0.044185449	normal	0.931153105	-0.255140595	normal	0.535304616	-0.529030791	normal	0.399865595	-0.277398782	normal	--	--	Molecular Function: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity (GO:0015018);; Cellular Component: membrane (GO:0016020);; 	"K10157|0|ptr:462813|B3GAT2; beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S) (EC:2.4.1.135); K10157 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 [EC:2.4.1.135] (A)"	Other types of O-glycan biosynthesis (ko00514)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyltransferase family 43	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 GN=B3GAT2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 2 isoform X1 [Ochotona princeps]
ENSG00000112312(GMNN)	--	23.00858095	467	24.93429618	511	28.85948519	572	29.16706496	603	28.67916565	586	23.97208741	503	0.848897296	0.336925489	normal	0.95508282	0.17566506	normal	0.950860531	-0.193203073	normal	0.709106598	0.105033697	normal	--	--	Biological Process: regulation of DNA replication (GO:0006275);; 	"K10749|9.38939e-139|hsa:51053|GMNN, Gem; geminin, DNA replication inhibitor; K10749 geminin (A)"	--	--	--	Geminin	Geminin GN=GMNN OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: geminin [Equus caballus] 
ENSG00000112319(EYA4)	--	17.98035333	1371	20.95698753	1515	19.6887315	1473	12.52136883	933	11.75653823	899	16.8205259	1274	0.081436749	-0.58531127	normal	0.001061119	-0.773337202	normal	0.959369628	-0.217443322	normal	0.005350194	-0.509200009	normal	--	--	--	K17622|0|mcc:707904|EYA4; eyes absent homolog 4-like; K17622 eyes absent homolog 4 [EC:3.1.3.48] (A)	--	[R]	General function prediction only	--	Eyes absent homolog 4 GN=EYA4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: eyes absent homolog 4 isoform X1 [Sorex araneus]
ENSG00000112320(SOBP)	--	1.135838232	71	1.012028936	57	0.793690792	54	0.6334996	38	1.392735353	60	0.47562346	26	0.426105013	-0.90542904	normal	0.975382544	0.051248718	normal	0.479158912	-1.020681654	normal	0.2878226	-0.575579475	normal	--	--	--	--	--	--	--	Sine oculis-binding protein;; MYM-type Zinc finger with FCS sequence motif	Sine oculis-binding protein homolog OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	sine oculis-binding protein homolog [Bos taurus] 
ENSG00000112333(NR2E1)	--	0	0	0	0	0	0	0	0	0.068974138	3	0.02182031	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08545|0|ptr:472088|NR2E1; nuclear receptor subfamily 2, group E, member 1; K08545 nuclear receptor subfamily 2 group E member 1 (A)"	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Nuclear receptor subfamily 2 group E member 1 GN=NR2E1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: nuclear receptor subfamily 2 group E member 1 [Felis catus]
ENSG00000112335(SNX3)	--	68.7588801	1591	65.0330976	1557	66.624834	1590	82.34245557	1936	76.00598	1795	82.49180075	1955	0.951773469	0.252091887	normal	0.971557649	0.183622129	normal	0.930231445	0.289601577	normal	0.163058589	0.241965091	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17918|9.99983e-117|rno:684097|Snx3; sorting nexin 3; K17918 sorting nexin-3/12 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain	Sorting nexin-3 GN=SNX3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-3 [Monodelphis domestica]
ENSG00000112337(SLC17A2)	--	0	0	0	0	0	0	0.028365879	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12300|0|hsa:10246|SLC17A2, NPT3; solute carrier family 17, member 2; K12300 MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Sodium-dependent phosphate transport protein 3 GN=SLC17A2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transport protein 3 isoform X2 [Ursus maritimus]
ENSG00000112339(HBS1L)	--	27.78889928	824	27.5337461	926	28.54665703	869	28.73646454	828	25.82801995	837	28.82924703	922	0.977094676	-0.023801561	normal	0.964003679	-0.166924238	normal	0.975952635	0.076989043	normal	0.896585106	-0.03864629	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K14416|0|ptr:463015|HBS1L; HBS1-like translational GTPase; K14416 elongation factor 1 alpha-like protein (A)	mRNA surveillance pathway (ko03015);; Legionellosis (ko05134)	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; HBS1 N-terminus;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2;; 50S ribosome-binding GTPase	HBS1-like protein GN=HBS1L OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: HBS1-like protein isoform X1 [Ailuropoda melanoleuca]
ENSG00000112343(TRIM38)	--	2.167474049	356	2.494343448	406	2.529927	406	2.37889545	391	3.059701525	502	3.135492127	517	0.964038926	0.10403061	normal	0.905395085	0.283828798	normal	0.848520857	0.33927065	normal	0.298462798	0.251427991	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12014|0|hsa:10475|TRIM38, RNF15, RORET; tripartite motif containing 38; K12014 tripartite motif-containing protein 38 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRIM38 GN=TRIM38 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 38 [Ceratotherium simum simum]
ENSG00000112357(PEX7)	--	5.470853991	106	3.037456775	67	3.422266235	75	3.35943149	68	3.760520544	78	3.006859707	61	0.622166598	-0.659255619	normal	0.966159437	0.193828741	normal	0.957784162	-0.299660865	normal	0.61184229	-0.282256474	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K13341|0|hsa:5191|PEX7, PBD9B, PTS2R, RCDP1, RD; peroxisomal biogenesis factor 7; K13341 peroxin-7 (A)"	Peroxisome (ko04146)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Peroxisomal targeting signal 2 receptor GN=PEX7 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal biogenesis factor 7 [Galeopterus variegatus]
ENSG00000112365(ZBTB24)	--	8.84511322	780	9.198168006	711	8.643369908	699	8.52011658	653	7.742677924	666	7.859202147	657	0.906308308	-0.286605384	normal	0.968496693	-0.115500048	normal	0.970858695	-0.097472967	normal	0.456726606	-0.169599779	normal	[R]	General function prediction only	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; 	K10503|0|nle:100604367|ZBTB24; zinc finger and BTB domain containing 24; K10503 zinc finger and BTB domain-containing protein 24 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; BTB/POZ domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 24 GN=ZBTB24 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	zinc finger and BTB domain-containing protein 24 [Bos taurus] 
ENSG00000112367(FIG4)	--	7.648014458	386	7.182161573	343	6.578504905	308	5.10247	274	5.45298174	258	6.90303274	306	0.403194837	-0.522773968	normal	0.715964272	-0.430069688	normal	0.967867655	-0.017603425	normal	0.198248451	-0.328551705	normal	--	--	Molecular Function: phosphoric ester hydrolase activity (GO:0042578);; 	--	--	[I]	Lipid transport and metabolism	SacI homology domain	Polyphosphoinositide phosphatase GN=FIG4 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	polyphosphoinositide phosphatase [Canis lupus familiaris]
ENSG00000112378(PERP)	--	103.736652	6239	108.025336	6488	110.617386	6532	99.291305	6022	87.2611005	5230	134.663605	8129	0.993593042	-0.081883838	normal	0.946154713	-0.332302972	normal	0.965548177	0.30719778	normal	0.98464129	-0.011181407	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K10136|1.91031e-120|hsa:64065|PERP, KCP1, KRTCAP1, PIGPC1, THW, dJ496H19.1; PERP, TP53 apoptosis effector; K10136 TP53 apoptosis effector (A)"	p53 signaling pathway (ko04115)	[R]	General function prediction only	PMP-22/EMP/MP20/Claudin family	p53 apoptosis effector related to PMP-22 GN=PERP OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PERP, TP53 apoptosis effector [Sus scrofa]"
ENSG00000112379(ARFGEF3)	--	4.374885	1234	4.87648	1365	4.447756503	1246	4.206254227	1186	3.90462498	1098	4.35944	1231	0.978913049	-0.087958923	normal	0.87139088	-0.335034672	normal	0.981807993	-0.025733326	normal	0.466156679	-0.150669217	normal	--	--	--	"K17572|0|hsa:57221|A7322, ARFGEF3, BIG3, C6orf92, PPP1R33, dJ171N11.1; KIAA1244; K17572 brefeldin A-inhibited guanine nucleotide-exchange protein 3 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Domain of unknown function (DUF1981)	Brefeldin A-inhibited guanine nucleotide-exchange protein 3 GN=ARFGEF3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: brefeldin A-inhibited guanine nucleotide-exchange protein 3-like [Tupaia chinensis]
ENSG00000112394(SLC16A10)	--	0.960132457	25	0.576728243	14	0.841236339	13	1.049301034	16	1.257121463	32	0.922813463	19	0.972292638	-0.626207221	normal	0.798924144	1.091380185	normal	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08187|0|ptr:462941|SLC16A10; solute carrier family 16 (aromatic amino acid transporter), member 10; K08187 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 10 (A)"	Thyroid hormone signaling pathway (ko04919);; Protein digestion and absorption (ko04974)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 10 GN=SLC16A10 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: monocarboxylate transporter 10 [Lipotes vexillifer]
ENSG00000112406(HECA)	--	1.476849	130	1.649364	141	2.258547	186	2.74172	234	2.08513765	187	2.505912	222	0.026853554	0.809935929	normal	0.866015781	0.382345313	normal	0.936058474	0.24513905	normal	0.118945821	0.471751936	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Headcase protein family homologue	Headcase protein homolog GN=HECA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: headcase protein homolog [Trichechus manatus latirostris]
ENSG00000112414(ADGRG6)	--	52.2102337	5467	39.14455118	4203	52.74441007	5377	32.386245	3598	31.11028252	3159	36.31899531	3871	0.032824566	-0.634164995	normal	0.731260477	-0.433197616	normal	0.532045346	-0.482226015	normal	0.005400313	-0.522389409	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08463|0|ggo:101132799|GPR126; G-protein coupled receptor 126 isoform 1; K08463 G protein-coupled receptor 126 (A)	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; CUB domain;; Latrophilin/CL-1-like GPS domain;; Pentaxin family	G-protein coupled receptor 126 (Precursor) GN=GPR126 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 126 isoform X1 [Galeopterus variegatus]
ENSG00000112419(PHACTR2)	--	5.385067915	776	5.908924092	884	5.25311433	766	4.093443404	598	4.558550176	689	4.906107085	679	0.700650415	-0.405825119	normal	0.775514239	-0.380230037	normal	0.957939707	-0.181842696	normal	0.078515282	-0.324254494	normal	--	--	--	--	--	[R]	General function prediction only	RPEL repeat	Phosphatase and actin regulator 2 GN=PHACTR2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: phosphatase and actin regulator 2 isoform 1 [Ceratotherium simum simum]
ENSG00000112425(EPM2A)	--	1.001227337	50	2.556266861	57	1.201584687	57	1.645216865	83	1.991964029	98	2.641854121	115	0.724275459	0.683887596	normal	0.502754693	0.745148183	normal	0.046189721	0.985540091	normal	0.040156521	0.831790099	normal	--	--	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; Molecular Function: starch binding (GO:2001070);; 	K14165|0|mcf:101867449|uncharacterized LOC101867449; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Starch binding domain"	Laforin GN=EPM2A OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: laforin [Oryctolagus cuniculus]
ENSG00000112473(SLC39A7)	--	54.03127488	2532	47.96203526	2388	49.63736942	2411	55.06693837	2653	56.89468098	2681	55.04044011	2614	0.988817324	0.036493374	normal	0.982854805	0.145454855	normal	0.985919126	0.108270811	normal	0.671187168	0.095337725	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14713|1.38344e-156|ptr:462603|SLC39A7; solute carrier family 39 (zinc transporter), member 7; K14713 solute carrier family 39 (zinc transporter), member 7 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter SLC39A7 GN=SLC39A7 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter SLC39A7 [Mustela putorius furo] 
ENSG00000112486(CCR6)	--	0.02211694	1	0	0	0	0	0	0	0.021469381	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04181|0|hsa:1235|CCR6, BN-1, C-C_CKR-6, CC-CKR-6, CCR-6, CD196, CKR-L3, CKRL3, CMKBR6, DCR2, DRY6, GPR29, GPRCY4, STRL22; chemokine (C-C motif) receptor 6; K04181 C-C chemokine receptor type 6 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	7 transmembrane receptor (rhodopsin family)	C-C chemokine receptor type 6 GN=CCR6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C-C chemokine receptor type 6 [Galeopterus variegatus]
ENSG00000112494(UNC93A)	--	0	0	0	0	0	0	0	0	0.135970092	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Ion channel regulatory protein UNC-93	Protein unc-93 homolog A GN=UNC93A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein unc-93 homolog A isoform X2 [Equus przewalskii]
ENSG00000112499(SLC22A2)	--	0	0	0	0	0	0	0.046462747	2	0	0	0.0231403	1	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08199|0|hsa:6582|SLC22A2, OCT2; solute carrier family 22 (organic cation transporter), member 2; K08199 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 2 (A)"	Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 2 GN=SLC22A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 22 member 2 [Ceratotherium simum simum]
ENSG00000112511(PHF1)	--	8.002263498	327	8.44839275	372	7.340597549	315	6.277966021	271	5.494516179	235	6.758167424	288	0.89856039	-0.300277482	normal	0.061961869	-0.680555243	normal	0.958969684	-0.136886906	normal	0.132007847	-0.374129328	normal	--	--	--	K11467|0|ggo:101149144|PHF1; PHD finger protein 1; K11467 polycomb-like protein 1 (A)	--	[R]	General function prediction only	Polycomb-like MTF2 factor 2;; PHD-finger	PHD finger protein 1 GN=PHF1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: PHD finger protein 1 [Pteropus alecto]
ENSG00000112514(CUTA)	--	131.7955728	1216	137.1564601	1309	130.78842	1265	104.5147277	1002	112.2102247	1005	111.055531	1043	0.895164298	-0.309661145	normal	0.72996215	-0.402164194	normal	0.918612986	-0.286312099	normal	0.042837134	-0.334470432	normal	[P]	Inorganic ion transport and metabolism	Biological Process: response to metal ion (GO:0010038);; 	"K03926|1.6406e-112|hsa:51596|CUTA, ACHAP, C6orf82; cutA divalent cation tolerance homolog (E. coli); K03926 periplasmic divalent cation tolerance protein (A)"	--	[P]	Inorganic ion transport and metabolism	CutA1 divalent ion tolerance protein	Protein CutA (Precursor) GN=CUTA OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: protein CutA isoform X3 [Oryctolagus cuniculus]
ENSG00000112530(PACRG)	--	0.0910058	2	0	0	0	0	0	0	0	0	0.12715	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Parkin co-regulated protein	Parkin coregulated gene protein GN=PACRG OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: parkin coregulated gene protein isoform X2 [Chrysochloris asiatica]
ENSG00000112531(QKI)	--	32.7761978	1771	43.86143964	2126	34.30435344	1903	44.44931661	2263	42.29598048	2174	36.55539813	2092	0.9054364	0.322592019	normal	0.987168095	0.010776206	normal	0.981896421	0.128218634	normal	0.453393299	0.149303017	normal	[A]	RNA processing and modification	Molecular Function: RNA binding (GO:0003723);; 	"K14945|0|ssc:492277|QKI, PqkI; QKI, KH domain containing, RNA binding; K14945 protein quaking (A)"	--	[A]	RNA processing and modification	KH domain	Protein quaking GN=QKI OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: protein quaking isoform 1 [Orcinus orca] 
ENSG00000112539(C6orf118)	--	0.108789	4	0	0	0.0262048	0	0	0	0.0527558	1	0.026922	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C6orf118 GN=C6orf118 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C6orf118 homolog [Ceratotherium simum simum]
ENSG00000112541(PDE10A)	--	2.387577043	338	2.000271659	257	3.044780801	386	3.9113026	508	2.581700123	343	2.1535483	294	0.239781894	0.554902833	normal	0.79088605	0.393005721	normal	0.76435975	-0.399277984	normal	0.722163476	0.200584449	normal	[T]	Signal transduction mechanisms	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; "	"K18438|0|hsa:10846|PDE10A, HSPDE10A; phosphodiesterase 10A (EC:3.1.4.35 3.1.4.17); K18438 cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10 [EC:3.1.4.17 3.1.4.35] (A)"	Purine metabolism (ko00230);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; GAF domain;; GAF domain;; GAF domain	"cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A GN=PDE10A OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A isoform X8 [Oryctolagus cuniculus]"
ENSG00000112559(MDFI)	--	0.288152955	6	0.038984712	1	0.640723214	5	0.19928647	6	0.84111805	12	0.074665369	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MyoD family inhibitor	MyoD family inhibitor GN=MDFI OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: myoD family inhibitor isoform X1 [Galeopterus variegatus]
ENSG00000112561(TFEB)	--	3.470959514	167	2.998415472	139	2.731456043	134	2.788434298	135	4.062636284	180	1.906318574	90	0.908423201	-0.33429269	normal	0.894667522	0.348148915	normal	0.675474066	-0.574562961	normal	0.813067828	-0.141727803	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K15590|0|hsa:7942|TFEB, ALPHATFEB, BHLHE35, TCFEB; transcription factor EB; K15590 transcription factor EB (A)"	--	[K]	Transcription	Domain of unknown function (DUF3371);; Helix-loop-helix DNA-binding domain	Transcription factor EB GN=TFEB OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor EB [Ochotona princeps]
ENSG00000112576(CCND3)	--	85.46850448	2798	83.6194052	2829	96.357198	3255	56.27184	1866	68.47093401	2123	69.4438158	2213	0.042224875	-0.614862675	normal	0.678694825	-0.435344706	normal	0.131733688	-0.564625354	normal	0.000165535	-0.538538046	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	K10152|0|ptr:462689|CCND3; cyclin D3; K10152 cyclin D3 (A)	Cell cycle (ko04110);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Jak-STAT signaling pathway (ko04630);; Measles (ko05162);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G1/S-specific cyclin-D3 GN=CCND3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	G1/S-specific cyclin-D3 [Ovis aries] 
ENSG00000112578(BYSL)	--	16.0105	630	18.3114	738	17.4274	706	15.5786	621	15.714	614	13.1734	522	0.9729711	-0.051464404	normal	0.906888398	-0.286164788	normal	0.587682898	-0.442802408	normal	0.203622148	-0.260942574	normal	--	--	--	"K14797|0|hsa:705|BYSL, BYSTIN; bystin-like; K14797 essential nuclear protein 1 (A)"	--	[W]	Extracellular structures	Bystin	Bystin GN=BYSL OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: bystin [Equus caballus]
ENSG00000112584(FAM120B)	--	8.621813326	639	7.124238425	610	6.516463282	536	7.52596464	664	8.820748081	763	7.980414859	650	0.974318719	0.024477312	normal	0.894414893	0.300779328	normal	0.917233509	0.269224498	normal	0.373458229	0.197151053	normal	--	--	--	--	--	--	--	"Glutathione S-transferase, N-terminal domain"	Constitutive coactivator of peroxisome proliferator-activated receptor gamma GN=FAM120B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: constitutive coactivator of peroxisome proliferator-activated receptor gamma [Ceratotherium simum simum]
ENSG00000112592(TBP)	--	9.122821	271	6.137239445	201	6.7216528	210	7.414522001	242	8.55866803	276	7.9418989	224	0.948264047	-0.192959558	normal	0.746449856	0.433254025	normal	0.964190591	0.084230567	normal	0.802953995	0.100186987	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K03120|2.69431e-156|mze:101470168|TATA-box-binding protein-like; K03120 transcription initiation factor TFIID TATA-box-binding protein (A)	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	"Transcription factor TFIID (or TATA-binding protein, TBP)"	TATA-box-binding protein GN=TBP OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: TATA-box-binding protein isoform X3 [Myotis brandtii]
ENSG00000112599(GUCA1B)	--	0.630841	20	0.277772497	13	0.339808052	15	0.54934714	25	0.496691598	22	0.307253105	14	0.985618203	0.272354789	normal	0.973050616	0.676519012	normal	--	--	--	0.74701496	0.322921643	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	K08328|4.86472e-146|ptr:472007|GUCA1B; guanylate cyclase activator 1B (retina); K08328 guanylate cyclase activator 1 (A)	Olfactory transduction (ko04740);; Phototransduction (ko04744)	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF hand;; Secreted protein acidic and rich in cysteine Ca binding region	Guanylyl cyclase-activating protein 2 GN=GUCA1B OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: guanylyl cyclase-activating protein 2 [Ursus maritimus]
ENSG00000112619(PRPH2)	--	0.0351217	2	0	0	0.0516003	2	0	0	0	0	0.0174148	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17343|0|hsa:5961|PRPH2, AOFMD, AVMD, CACD2, DS, MDBS1, PRPH, RDS, RP7, TSPAN22, rd2; peripherin 2 (retinal degeneration, slow); K17343 peripherin-2 (A)"	--	[R]	General function prediction only	Tetraspanin family	Peripherin-2 GN=PRPH2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: peripherin-2 isoform 1 [Tursiops truncatus] 
ENSG00000112624(GLTSCR1L)	--	3.526844931	405	3.585401329	410	2.842055741	320	2.54336669	291	2.244242407	258	3.152585159	366	0.449932864	-0.505461309	normal	0.046689112	-0.686457413	normal	0.950050985	0.184663728	normal	0.220392555	-0.331813652	normal	--	--	--	--	--	--	--	Glioma tumor suppressor candidate region	GLTSCR1-like protein GN=GLTSCR1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	hypothetical protein PANDA_002441 [Ailuropoda melanoleuca]
ENSG00000112640(PPP2R5D)	--	15.48798573	908	13.37186288	848	15.18296738	964	14.35021068	820	13.66333187	800	11.1407542	726	0.961644527	-0.177584255	normal	0.972005531	-0.10529745	normal	0.666416865	-0.416599335	normal	0.225907284	-0.234754703	normal	--	--	Cellular Component: protein phosphatase type 2A complex (GO:0000159);; Biological Process: signal transduction (GO:0007165);; Molecular Function: protein phosphatase regulator activity (GO:0019888);; 	"K11584|0|ptr:462705|PPP2R5D; protein phosphatase 2, regulatory subunit B', delta; K11584 serine/threonine-protein phosphatase 2A regulatory subunit B' (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Dopaminergic synapse (ko04728)	[T]	Signal transduction mechanisms	Protein phosphatase 2A regulatory B subunit (B56 family)	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform GN=PPP2R5D OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform [Equus przewalskii]
ENSG00000112651(MRPL2)	--	22.654456	340	20.7669478	314	23.063453	375	27.081955	422	25.694831	444	21.467762	375	0.908965631	0.279739565	normal	0.545804472	0.476430185	normal	0.9692586	-0.008258139	normal	0.329392599	0.24904949	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02886|0|ggo:101148682|MRPL2; 39S ribosomal protein L2, mitochondrial; K02886 large subunit ribosomal protein L2 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal Proteins L2, C-terminal domain;; Ribosomal Proteins L2, RNA binding domain"	"39S ribosomal protein L2, mitochondrial (Precursor) GN=MRPL2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L2, mitochondrial [Equus caballus] "
ENSG00000112655(PTK7)	--	3.771719394	322	3.893907729	267	2.501062054	227	0.935831799	80	1.713955541	138	0.955578273	82	1.11E-16	-2.018879402	down	0.00105687	-0.965846	normal	9.24E-08	-1.460400278	down	1.45E-06	-1.464848079	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05127|0|hsa:5754|PTK7, CCK-4, CCK4; protein tyrosine kinase 7 (inactive) (EC:2.7.10.1); K05127 PTK7 protein tyrosine kinase 7 [EC:2.7.10.1] (A)"	--	[RP]	General function prediction only;; Inorganic ion transport and metabolism	Protein tyrosine kinase;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Protein kinase domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein E;; Penicillin-Binding Protein C-terminus Family;; Immunoglobulin C1-set domain	Inactive tyrosine-protein kinase 7 (Precursor) GN=PTK7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inactive tyrosine-protein kinase 7 isoform 1 [Ceratotherium simum simum]
ENSG00000112658(SRF)	--	10.166969	843	10.64472	900	12.77089	1077	13.6399	1117	11.205922	916	11.38883	941	0.785207899	0.37459762	normal	0.97793347	0.003989395	normal	0.957809594	-0.202738258	normal	0.847502741	0.055304148	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein dimerization activity (GO:0046983);; 	K04378|0|pps:100988350|SRF; serum response factor (c-fos serum response element-binding transcription factor); K04378 serum response factor (A)	MAPK signaling pathway (ko04010);; cGMP-PKG signaling pathway (ko04022);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[K]	Transcription	SRF-type transcription factor (DNA-binding and dimerisation domain)	Serum response factor GN=SRF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: serum response factor, partial [Tupaia chinensis]"
ENSG00000112659(CUL9)	--	2.892028004	482	2.78311416	468	2.7892053	476	2.69416925	446	2.6462064	439	3.88494054	651	0.960623975	-0.142349806	normal	0.963857324	-0.113335925	normal	0.597104434	0.442198507	normal	0.844653371	0.087146143	normal	--	--	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	"K11970|0|hsa:23113|CUL9, H7AP1, PARC; cullin 9; K11970 p53-associated parkin-like cytoplasmic protein (A)"	--	--	--	"Cullin family;; Mouse development and cellular proliferation protein Cullin-7;; IBR domain;; Anaphase-promoting complex, subunit 10 (APC10)"	Cullin-9 GN=CUL9 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cullin-9 [Galeopterus variegatus]
ENSG00000112667(DNPH1)	--	65.641357	570	65.85485	618	66.96197	628	59.34111	527	61.820759	531	61.434174	538	0.962168176	-0.143588543	normal	0.933607578	-0.239688063	normal	0.938182077	-0.230848582	normal	0.362667182	-0.207342469	normal	--	--	Biological Process: deoxyribonucleoside monophosphate catabolic process (GO:0009159);; Molecular Function: nucleoside deoxyribosyltransferase activity (GO:0050144);; Molecular Function: deoxyribonucleoside 5'-monophosphate N-glycosidase activity (GO:0070694);; 	--	--	--	--	Nucleoside 2-deoxyribosyltransferase	2'-deoxynucleoside 5'-phosphate N-hydrolase 1 {ECO:0000255|HAMAP-Rule:MF_03036} OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 [Pantholops hodgsonii]
ENSG00000112679(DUSP22)	--	9.295623058	396	8.340114857	397	8.397355682	341	8.393879265	354	6.842952325	315	8.356073177	374	0.948286184	-0.191795723	normal	0.83871148	-0.353697414	normal	0.961451358	0.124447929	normal	0.641390743	-0.142023719	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K14165|3.26636e-154|hsa:56940|DUSP22, JKAP, JSP-1, JSP1, LMW-DSP2, LMWDSP2, MKP-x, MKPX, VHX; dual specificity phosphatase 22 (EC:3.1.3.16 3.1.3.48); K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 22 GN=DUSP22 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 22 isoform X1 [Felis catus] 
ENSG00000112685(EXOC2)	--	10.14341173	840	8.213388597	674	10.24577817	836	8.426966786	695	8.806075891	724	8.640344972	710	0.891759154	-0.303597012	normal	0.97191301	0.081637793	normal	0.936537401	-0.24349683	normal	0.467145532	-0.163364736	normal	--	--	--	"K17637|0|hsa:55770|EXOC2, SEC5, SEC5L1, Sec5p; exocyst complex component 2; K17637 exocyst complex component 2 (A)"	Ras signaling pathway (ko04014)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec5;; IPT/TIG domain	Exocyst complex component 2 GN=EXOC2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 2 isoform X1 [Tupaia chinensis]
ENSG00000112695(COX7A2)	--	109.5587319	1111	112.3462185	1139	105.809725	1073	114.98661	1136	99.7082138	990	113.9251596	1123	0.980884226	0.001270018	normal	0.951855599	-0.223375445	normal	0.979488782	0.057337413	normal	0.842418005	-0.053865225	normal	--	--	--	"K02270|3.89565e-81|hsa:1347|COX7A2, COX7AL, COX7AL1, COXVIIAL, COXVIIa-L, VIIAL; cytochrome c oxidase subunit VIIa polypeptide 2 (liver) (EC:1.9.3.1); K02270 cytochrome c oxidase subunit 7a (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	Cytochrome c oxidase subunit VIIa	"Cytochrome c oxidase subunit 7A2, mitochondrial (Precursor) GN=COX7A2 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC103657485 [Ursus maritimus]
ENSG00000112697(TMEM30A)	--	42.0954362	2596	38.76820375	2393	42.64669639	2546	61.89856704	3820	63.46765502	3876	53.84179161	3303	0.273928396	0.526191845	normal	0.013339797	0.6739839	normal	0.86503756	0.367061171	normal	0.000286571	0.524173809	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[DKT]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Signal transduction mechanisms"	LEM3 (ligand-effect modulator 3) family / CDC50 family	Cell cycle control protein 50A GN=TMEM30A OS=Homo sapiens (Human) PE=1 SV=1	DKT	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Signal transduction mechanisms"	PREDICTED: LOW QUALITY PROTEIN: cell cycle control protein 50A [Odobenus rosmarus divergens]
ENSG00000112699(GMDS)	--	6.0661171	194	4.697583891	152	6.048194258	196	8.68528	274	8.613044	274	8.76392	275	0.679849914	0.464180385	normal	0.013771087	0.822500301	normal	0.645192862	0.477164155	normal	0.022671746	0.581701889	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K01711|0|pps:100967696|GMDS; GDP-mannose 4,6-dehydratase; K01711 GDPmannose 4,6-dehydratase [EC:4.2.1.47] (A)"	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	NAD dependent epimerase/dehydratase family;; RmlD substrate binding domain	"GDP-mannose 4,6 dehydratase GN=GMDS OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: GDP-mannose 4,6 dehydratase [Pteropus alecto]"
ENSG00000112701(SENP6)	--	15.98779257	1354	15.998091	1457	16.47227813	1387	12.07880847	1126	14.69219771	1294	16.28953424	1409	0.911923613	-0.296483612	normal	0.966197487	-0.192377785	normal	0.983274744	0.014396808	normal	0.447159962	-0.153270515	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K08595|0|hsa:26054|SENP6, SSP1, SUSP1; SUMO1/sentrin specific peptidase 6 (EC:3.4.22.68); K08595 sentrin-specific protease 6 [EC:3.4.22.68] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ulp1 protease family, C-terminal catalytic domain"	Sentrin-specific protease 6 GN=SENP6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sentrin-specific protease 6 [Oryctolagus cuniculus]
ENSG00000112706(IMPG1)	--	0.085958662	2	0	0	0.299800064	6	0.042281468	1	0.041340317	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SEA domain	Interphotoreceptor matrix proteoglycan 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: interphotoreceptor matrix proteoglycan 1 [Galeopterus variegatus]
ENSG00000112715(VEGFA)	--	24.07588561	1486	18.66248851	1163	17.67583376	1106	25.6935557	1622	20.37011279	1277	24.86680063	1529	0.98144209	0.095413001	normal	0.976549703	0.11334019	normal	0.513971738	0.458410237	normal	0.408582749	0.216106318	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Molecular Function: heparin binding (GO:0008201);; Cellular Component: membrane (GO:0016020);; 	"K05448|3.71904e-177|hsa:7422|VEGFA, MVCD1, VEGF, VPF; vascular endothelial growth factor A; K05448 vascular endothelial growth factor A (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Bladder cancer (ko05219);; Rheumatoid arthritis (ko05323)	--	--	VEGF heparin-binding domain;; PDGF/VEGF domain	Vascular endothelial growth factor A (Precursor) GN=VEGFA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	vascular endothelial growth factor [Sus scrofa]
ENSG00000112739(PRPF4B)	--	16.22965375	1683	20.217721	1937	17.93845142	1764	19.85346772	2039	21.56098824	2159	18.776794	1881	0.955877146	0.245790236	normal	0.98125577	0.135012855	normal	0.983948921	0.084287859	normal	0.434955362	0.153706082	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08827|0|cjc:100404733|PRPF4B; pre-mRNA processing factor 4B; K08827 serine/threonine-protein kinase PRP4 [EC:2.7.11.1] (A)	--	[A]	RNA processing and modification	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase PRP4 homolog GN=PRPF4B OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: serine/threonine-protein kinase PRP4 homolog [Oryctolagus cuniculus]
ENSG00000112742(TTK)	--	12.21398389	719	12.80506247	738	15.8480104	901	12.11642886	714	10.04789182	589	12.2657793	718	0.974969713	-0.040812442	normal	0.838510364	-0.345984252	normal	0.854420343	-0.335203031	normal	0.227552083	-0.243366915	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08866|0|hsa:7272|TTK, CT96, ESK, MPH1, MPS1, MPS1L1, PYT; TTK protein kinase (EC:2.7.12.1); K08866 serine/threonine-protein kinase TTK/MPS1 [EC:2.7.12.1] (A)"	Cell cycle (ko04110)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	Dual specificity protein kinase TTK GN=TTK OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: dual specificity protein kinase TTK isoform X1 [Galeopterus variegatus] 
ENSG00000112759(SLC29A1)	--	38.6574743	1284	35.14548524	1182	36.72791286	1248	40.62810023	1358	35.75501791	1187	25.6131735	859	0.98185531	0.049947896	normal	0.980975388	-0.015317103	normal	0.170817855	-0.546376529	normal	0.640616102	-0.148198282	normal	--	--	Molecular Function: nucleoside transmembrane transporter activity (GO:0005337);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15014|0|hsa:2030|SLC29A1, ENT1; solute carrier family 29 (equilibrative nucleoside transporter), member 1; K15014 solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3 (A)"	Alcoholism (ko05034)	[F]	Nucleotide transport and metabolism	Nucleoside transporter	Equilibrative nucleoside transporter 1 GN=SLC29A1 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: equilibrative nucleoside transporter 1 isoform X2 [Tupaia chinensis] 
ENSG00000112761(WISP3)	--	0.12458	5	0.0498167	2	0.0499681	1	0.024573308	1	0.024141	0	0.024690129	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Insulin-like growth factor binding protein;; Cystine-knot domain;; Thrombospondin type 1 domain	WNT1-inducible-signaling pathway protein 3 (Precursor) GN=WISP3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: WNT1-inducible-signaling pathway protein 3 [Trichechus manatus latirostris]
ENSG00000112763(BTN2A1)	--	9.356423442	513	9.12947652	528	8.15302885	522	8.29800341	533	9.167878663	573	9.74983006	632	0.971929097	0.024273124	normal	0.967767686	0.096305825	normal	0.918504708	0.266879632	normal	0.617050764	0.132438739	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06712|0|ptr:471891|BTN2A1; butyrophilin subfamily 2 member A1; K06712 butyrophilin (A)	--	--	--	SPRY domain;; SPRY-associated domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain	Butyrophilin subfamily 2 member A1 (Precursor) GN=BTN2A1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: butyrophilin subfamily 2 member A2-like [Vicugna pacos]
ENSG00000112769(LAMA4)	--	2.78849487	162	1.332533781	74	1.885210052	117	0.953179043	69	0.562207991	45	0.220935766	11	0.000133615	-1.243522675	down	0.712782562	-0.719963205	normal	5.55E-16	-3.25135662	down	0.039985825	-1.522982567	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Biological Process: cell adhesion (GO:0007155);; Biological Process: regulation of cell adhesion (GO:0030155);; Biological Process: regulation of cell migration (GO:0030334);; Biological Process: regulation of embryonic development (GO:0045995);; 	"K06241|0|hsa:3910|LAMA4, CMD1JJ, LAMA3, LAMA4*-1; laminin, alpha 4; K06241 laminin, alpha 4 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; African trypanosomiasis (ko05143);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin G domain;; Laminin Domain I;; Laminin G domain;; Laminin Domain II;; Laminin EGF-like (Domains III and V);; Concanavalin A-like lectin/glucanases superfamily	Laminin subunit alpha-4 (Precursor) GN=LAMA4 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: laminin subunit alpha-4 isoform X3 [Equus caballus]
ENSG00000112773(FAM46A)	--	3.877767173	347	6.331911415	567	3.522405527	311	3.103180143	280	3.6363404	323	5.368285019	482	0.861873583	-0.338667971	normal	0.001216413	-0.830266555	normal	0.09816351	0.621381222	normal	0.800513651	-0.195398181	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF1693)	Protein FAM46A GN=FAM46A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM46A-like isoform X1 [Bubalus bubalis]
ENSG00000112782(CLIC5)	--	0	0	0.025607479	1	0.026834122	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05025|0|hsa:53405|CLIC5, DFNB102, DFNB103, MST130, MSTP130; chloride intracellular channel 5; K05025 chloride intracellular channel protein 5 (A)"	--	[P]	Inorganic ion transport and metabolism	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Chloride intracellular channel protein 5 GN=CLIC5 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: chloride intracellular channel protein 5 isoform 1 [Ceratotherium simum simum]
ENSG00000112787(FBRSL1)	--	19.711755	1337	18.84434079	1262	20.239118	1387	21.76873972	1446	22.52664	1521	19.324125	1335	0.980969952	0.082145043	normal	0.948174994	0.247611082	normal	0.981727579	-0.063349079	normal	0.704918661	0.088819719	normal	--	--	--	--	--	--	--	Autism susceptibility gene 2 protein	Fibrosin-1-like protein GN=FBRSL1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: fibrosin-like 1 [Orcinus orca]
ENSG00000112796(ENPP5)	--	0.050456556	2	0.050948779	2	0.049935985	2	0	0	0.0714793	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; 	"K18398|0|hsa:59084|ENPP5, NPP-5; ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative); K18398 ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [EC:3.1.-.-] (A)"	--	[R]	General function prediction only	Type I phosphodiesterase / nucleotide pyrophosphatase	Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ectonucleotide pyrophosphatase/phosphodiesterase family member 5 [Equus caballus] 
ENSG00000112812(PRSS16)	--	3.022242281	87	1.868075	55	2.509261282	72	1.621597	55	2.4262774	73	3.140495134	92	0.698042752	-0.677235785	normal	0.944251685	0.377991321	normal	0.942222781	0.339031417	normal	0.989067348	0.020364845	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; 	"K09649|0|hsa:10279|PRSS16, TSSP; protease, serine, 16 (thymus); K09649 protease, serine, 16 (thymus) [EC:3.4.-.-] (A)"	--	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Serine carboxypeptidase S28	Thymus-specific serine protease (Precursor) GN=PRSS16 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thymus-specific serine protease [Galeopterus variegatus]
ENSG00000112818(MEP1A)	--	0	0	0.0178309	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K01395|0|ptr:462745|MEP1A; meprin A, alpha (PABA peptide hydrolase); K01395 meprin A [EC:3.4.24.18] (A)"	Protein digestion and absorption (ko04974)	[O]	"Posttranslational modification, protein turnover, chaperones"	Astacin (Peptidase family M12A);; MAM domain;; MATH domain;; EGF-like domain	Meprin A subunit alpha (Precursor) GN=MEP1A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: meprin A subunit alpha [Bison bison bison]
ENSG00000112837(TBX18)	--	8.25401387	704	9.41096229	781	10.4786703	781	13.39338612	1237	20.16998	1663	15.04812889	1283	0.000823259	0.78106421	normal	8.34E-08	1.067518086	up	0.005504585	0.70675683	normal	5.94E-05	0.863520023	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10183|0|hsa:9096|TBX18; T-box 18; K10183 T-box protein 18 (A)	--	[K]	Transcription	T-box	T-box transcription factor TBX18 GN=TBX18 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: T-box transcription factor TBX18 isoform X1 [Pantholops hodgsonii]
ENSG00000112851(ERBIN)	--	20.6262083	2542	25.0907977	3112	24.38022421	3010	26.41663902	3305	23.1099291	2978	28.6535281	3666	0.894477294	0.347669245	normal	0.98854793	-0.084882692	normal	0.958345208	0.276026003	normal	0.355000751	0.178662113	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K12796|0|mcf:102136355|ERBB2IP; erbb2 interacting protein; K12796 erbb2-interacting protein (A)	NOD-like receptor signaling pathway (ko04621)	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; PDZ domain (Also known as DHR or GLGF)	Protein LAP2 GN=ERBB2IP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein LAP2 isoform X2 [Galeopterus variegatus]
ENSG00000112852(PCDHB2)	--	3.689797103	183	3.810302584	227	2.558424078	140	4.747487118	233	4.02984755	231	4.426417109	275	0.90213095	0.315303376	normal	0.965897984	0.003749237	normal	0.000991193	0.958191794	normal	0.161445965	0.40474789	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56133|PCDHB2, PCDH-BETA2; protocadherin beta 2; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-2 (Precursor) GN=PCDHB2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protocadherin beta-2 [Equus przewalskii]
ENSG00000112855(HARS2)	--	55.23410468	1994	56.0455	2114	53.063806	1990	65.91820599	2422	65.33778934	2348	58.74256207	2120	0.958666039	0.249526525	normal	0.982754619	0.129942243	normal	0.985271841	0.082943315	normal	0.429782446	0.154529376	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K01892|0|pps:100969951|HARS2; histidyl-tRNA synthetase 2, mitochondrial; K01892 histidyl-tRNA synthetase [EC:6.1.1.21] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"Histidyl-tRNA synthetase;; tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain;; Anticodon binding domain of tRNAs"	"Probable histidine--tRNA ligase, mitochondrial (Precursor) GN=HARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable histidine--tRNA ligase, mitochondrial [Ceratotherium simum simum]"
ENSG00000112874(NUDT12)	--	2.192555353	93	1.574989216	79	1.88351372	87	2.019294477	96	2.196225817	95	2.54804051	123	0.971565963	0.014731882	normal	0.956955223	0.240446186	normal	0.83409577	0.484168207	normal	0.613538258	0.257401739	normal	[L]	"Replication, recombination and repair"	Molecular Function: protein binding (GO:0005515);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; 	K03426|0|ptr:461977|NUDT12; nudix (nucleoside diphosphate linked moiety X)-type motif 12; K03426 NAD+ diphosphatase [EC:3.6.1.22] (A)	Nicotinate and nicotinamide metabolism (ko00760);; Peroxisome (ko04146)	[R]	General function prediction only	Ankyrin repeats (many copies);; NUDIX domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; NADH pyrophosphatase zinc ribbon domain;; NADH pyrophosphatase-like rudimentary NUDIX domain	Peroxisomal NADH pyrophosphatase NUDT12 GN=NUDT12 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: peroxisomal NADH pyrophosphatase NUDT12 isoform 1 [Ovis aries] 
ENSG00000112877(CEP72)	--	5.642765073	332	5.21946644	306	6.029439503	346	4.275692486	264	4.301587357	251	4.4859207	294	0.839562859	-0.359606539	normal	0.896219503	-0.305600176	normal	0.931066721	-0.242098055	normal	0.248831319	-0.303251003	normal	--	--	--	K16532|0|hsa:55722|CEP72; centrosomal protein 72kDa; K16532 centrosomal protein CEP72 (A)	--	--	--	Leucine Rich repeats (2 copies);; Leucine rich repeat	Centrosomal protein of 72 kDa GN=CEP72 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: centrosomal protein of 72 kDa [Ceratotherium simum simum]
ENSG00000112893(MAN2A1)	--	17.222594	1901	17.26180122	1935	16.80210393	1855	23.6114667	2662	20.479951	2286	18.902746	2092	0.570347986	0.454608002	normal	0.967825896	0.218907728	normal	0.977487421	0.165045451	normal	0.082443058	0.284883805	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: alpha-mannosidase activity (GO:0004559);; Biological Process: mannose metabolic process (GO:0006013);; 	"K01231|0|hsa:4124|MAN2A1, AMan_II, GOLIM7, MANA2, MANII; mannosidase, alpha, class 2A, member 1 (EC:3.2.1.114); K01231 alpha-mannosidase II [EC:3.2.1.114] (A)"	N-Glycan biosynthesis (ko00510)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolases family 38 N-terminal domain;; Glycosyl hydrolases family 38 C-terminal domain;; Alpha mannosidase, middle domain"	Alpha-mannosidase 2 GN=MAN2A1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: alpha-mannosidase 2 [Galeopterus variegatus]
ENSG00000112941(PAPD7)	--	13.24332321	1625	13.91377238	1691	13.23787655	1559	14.19339934	1844	15.57316271	1826	14.6635872	1786	0.977451619	0.151432208	normal	0.982909439	0.089306678	normal	0.970929543	0.187649525	normal	0.489567053	0.14104487	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	K03514|0|pon:100444704|PAPD7; PAP associated domain containing 7; K03514 non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] (A)	RNA degradation (ko03018)	[L]	"Replication, recombination and repair"	Cid1 family poly A polymerase;; Nucleotidyltransferase domain	Non-canonical poly(A) RNA polymerase PAPD7 GN=PAPD7 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: non-canonical poly(A) RNA polymerase PAPD7 isoform X1 [Monodelphis domestica]
ENSG00000112964(GHR)	--	0.054553916	4	0.041266744	3	0.027415089	1	0.040977748	3	0.05315693	3	0.095148821	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K05080|0|ptr:471560|GHR; growth hormone receptor; K05080 growth hormone receptor (A)	Cytokine-cytokine receptor interaction (ko04060);; Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630)	--	--	"Growth hormone receptor binding;; Erythropoietin receptor, ligand binding;; Fibronectin type III domain"	Growth hormone-binding protein (Precursor) GN=GHR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: growth hormone receptor isoform X2 [Equus caballus]
ENSG00000112972(HMGCS1)	--	65.173655	3709	83.364521	4798	75.95341422	4258	29.935567	1720	34.02841446	1921	79.39442174	4502	6.72E-10	-1.13874316	down	1.06E-13	-1.341309746	down	0.991857541	0.072073768	normal	0.248448535	-0.666887059	normal	[I]	Lipid transport and metabolism	Molecular Function: hydroxymethylglutaryl-CoA synthase activity (GO:0004421);; Biological Process: isoprenoid biosynthetic process (GO:0008299);; 	"K01641|0|hsa:3157|HMGCS1, HMGCS; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) (EC:2.3.3.10); K01641 hydroxymethylglutaryl-CoA synthase [EC:2.3.3.10] (A)"	"Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Butanoate metabolism (ko00650);; Terpenoid backbone biosynthesis (ko00900)"	[I]	Lipid transport and metabolism	Hydroxymethylglutaryl-coenzyme A synthase C terminal;; Hydroxymethylglutaryl-coenzyme A synthase N terminal	"Hydroxymethylglutaryl-CoA synthase, cytoplasmic GN=HMGCS1 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: hydroxymethylglutaryl-CoA synthase, cytoplasmic [Vicugna pacos]"
ENSG00000112977(DAP)	--	39.50416215	1854	33.82657159	1588	35.10573058	1654	56.22340811	2642	58.30140668	2723	56.00940788	2648	0.452534814	0.479822332	normal	0.001381458	0.756003409	normal	0.010914525	0.67016381	normal	6.43E-06	0.631776308	normal	--	--	--	--	--	--	--	Death-associated protein	Death-associated protein 1 GN=DAP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: death-associated protein 1 [Felis catus]
ENSG00000112983(BRD8)	--	13.539927	991	17.23202565	1269	16.15842153	1155	16.48536973	1213	15.12683989	1093	19.32194211	1333	0.934836402	0.260424892	normal	0.949016001	-0.23652118	normal	0.963034122	0.198250672	normal	0.790457301	0.070688355	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	K11321|0|pps:100992161|BRD8; bromodomain containing 8; K11321 bromodomain-containing protein 8 (A)	--	--	--	Bromodomain	Bromodomain-containing protein 8 GN=BRD8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: bromodomain-containing protein 8 isoform X2 [Equus przewalskii]
ENSG00000112984(KIF20A)	--	16.62930336	1187	16.65364	1176	16.368668	1148	22.79395052	1614	21.11667001	1493	19.38596031	1382	0.696210198	0.412029469	normal	0.890533152	0.322530685	normal	0.939527649	0.259032113	normal	0.039985393	0.332802791	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10402|0|hsa:10112|KIF20A, MKLP2, RAB6KIFL; kinesin family member 20A; K10402 kinesin family member 20 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF20A GN=KIF20A OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF20A [Galeopterus variegatus]
ENSG00000112992(NNT)	--	12.61331337	846	11.56031796	882	14.86039793	924	23.2338854	1586	22.30196549	1445	20.93255295	1463	3.93E-05	0.874652975	normal	0.009659498	0.689859452	normal	0.018393211	0.653815861	normal	2.06E-07	0.739570376	normal	[C]	Energy production and conversion	--	"K00323|0|hsa:23530|NNT, GCCD4; nicotinamide nucleotide transhydrogenase (EC:1.6.1.2); K00323 NAD(P) transhydrogenase [EC:1.6.1.2] (A)"	Nicotinate and nicotinamide metabolism (ko00760)	--	--	"NAD(P) transhydrogenase beta subunit;; Alanine dehydrogenase/PNT, C-terminal domain;; Alanine dehydrogenase/PNT, N-terminal domain;; Domain of unknown function (DUF3814)"	"NAD(P) transhydrogenase, mitochondrial (Precursor) GN=NNT OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: NAD(P) transhydrogenase, mitochondrial isoform X1 [Capra hircus] "
ENSG00000112996(MRPS30)	--	16.98596	950	18.28347	1027	21.00067	1106	21.66565	1219	23.62547	1268	16.43529	1062	0.871711911	0.328396578	normal	0.922615992	0.282317285	normal	0.978894911	-0.066765889	normal	0.357353094	0.181730109	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: mitochondrion (GO:0005739);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K17409|0|ptr:461887|MRPS30; mitochondrial ribosomal protein S30; K17409 small subunit ribosomal protein S30 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial 28S ribosomal protein S30 (PDCD9)	"28S ribosomal protein S30, mitochondrial GN=MRPS30 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S30, mitochondrial [Galeopterus variegatus]"
ENSG00000113013(HSPA9)	--	160.3440065	10334	168.703144	10957	162.506523	10392	152.559183	9879	151.4540066	9683	157.7050064	10104	0.995516936	-0.095779568	normal	0.991410792	-0.199724058	normal	0.996127236	-0.048831027	normal	0.628037851	-0.116084443	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Biological Process: cell morphogenesis (GO:0000902);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K04043|0|hsa:3313|HSPA9, CRP40, CSA, GRP-75, GRP75, HEL-S-124m, HSPA9B, MOT, MOT2, MTHSP75, PBP74; heat shock 70kDa protein 9 (mortalin); K04043 molecular chaperone DnaK (A)"	RNA degradation (ko03018);; Tuberculosis (ko05152)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Hsp70 protein;; FGGY family of carbohydrate kinases, C-terminal domain"	"Stress-70 protein, mitochondrial (Precursor) GN=HSPA9 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: stress-70 protein, mitochondrial [Ovis aries] "
ENSG00000113048(MRPS27)	--	44.52173814	2224	45.18824223	1891	51.66229173	2140	42.38752058	1785	41.72455287	1842	40.7941661	1854	0.8722338	-0.347796139	normal	0.984909124	-0.059254844	normal	0.967752501	-0.215097536	normal	0.236559506	-0.21152946	normal	--	--	--	"K17406|0|hsa:23107|MRPS27, MRP-S27, S27mt; mitochondrial ribosomal protein S27; K17406 small subunit ribosomal protein S27 (A)"	--	[S]	Function unknown	Mitochondrial 28S ribosomal protein S27	"28S ribosomal protein S27, mitochondrial GN=MRPS27 OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S27, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000113068(PFDN1)	--	63.47261	1181	58.08867	1216	51.991868	1154	52.08967302	1173	56.49288	1147	48.274154	1097	0.980839941	-0.040585235	normal	0.97684252	-0.105569185	normal	0.978519697	-0.081261903	normal	0.755825864	-0.076951817	normal	--	--	Biological Process: protein folding (GO:0006457);; Cellular Component: prefoldin complex (GO:0016272);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K09548|5.8858e-65|hsa:5201|PFDN1, PDF, PFD1; prefoldin subunit 1; K09548 prefoldin subunit 1 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prefoldin subunit	Prefoldin subunit 1 GN=PFDN1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	prefoldin subunit 1 [Canis lupus familiaris] 
ENSG00000113070(HBEGF)	--	1.534994	70	1.584321159	71	2.373661	107	2.016333	91	0.989221	44	1.142500865	51	0.943255603	0.341097902	normal	0.766734053	-0.692816535	normal	0.029115795	-1.055245731	normal	0.488222444	-0.43762393	normal	--	--	--	"K08523|3.09218e-117|hsa:1839|HBEGF, DTR, DTS, DTSF, HEGFL; heparin-binding EGF-like growth factor; K08523 heparin-binding EGF-like growth factor (A)"	ErbB signaling pathway (ko04012);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Proteoglycans in cancer (ko05205)	--	--	EGF-like domain;; Human growth factor-like EGF	Heparin-binding EGF-like growth factor (Precursor) GN=HBEGF OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: proheparin-binding EGF-like growth factor [Galeopterus variegatus]
ENSG00000113073(SLC4A9)	--	0.078203618	4	0	0	0.08144737	4	0.05895176	3	0	0	0.033178777	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13860|0|mcf:102120397|SLC4A9; solute carrier family 4, sodium bicarbonate cotransporter, member 9; K13860 solute carrier family 4 (sodium bicarbonate cotransporter), member 9 (A)"	--	[P]	Inorganic ion transport and metabolism	HCO3- transporter family;; Band 3 cytoplasmic domain	Anion exchange protein 4 GN=SLC4A9 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: anion exchange protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000113083(LOX)	--	0.661713135	50	0.61049	35	0.532803	29	2.112210062	162	2.606097	175	1.711655	111	1.70E-07	1.635718814	up	3.76E-13	2.252423587	up	4.29E-07	1.874590051	up	1.06E-07	1.951812018	up	--	--	"Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (GO:0016641);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00277|0|ptr:471614|LOX; lysyl oxidase; K00277 protein-lysine 6-oxidase [EC:1.4.3.13] (A)	--	--	--	Lysyl oxidase	Protein-lysine 6-oxidase (Precursor) GN=LOX OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-lysine 6-oxidase isoform 1 [Dasypus novemcinctus]
ENSG00000113100(CDH9)	--	0.164772601	1	0.084133183	5	0	0	0.01677367	1	0.065542756	3	0.016753877	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06801|0|hsa:1007|CDH9; cadherin 9, type 2 (T1-cadherin); K06801 cadherin 9, type 2, T1-cadherin (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-9 (Precursor) GN=CDH9 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: cadherin-9 [Ailuropoda melanoleuca] 
ENSG00000113108(APBB3)	--	13.7580168	591	15.863808	666	13.973458	605	15.707489	641	14.73980966	594	16.623506	686	0.970583997	0.086118961	normal	0.954312577	-0.186038198	normal	0.958564956	0.172576638	normal	0.94988918	0.023887461	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Phosphotyrosine interaction domain (PTB/PID);; WW domain	Amyloid beta A4 precursor protein-binding family B member 3 GN=APBB3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: amyloid beta A4 precursor protein-binding family B member 3 [Tupaia chinensis]
ENSG00000113119(TMCO6)	--	6.35918	193	4.80187	151	4.843786	152	4.628843	141	5.670371	171	3.90385	119	0.730380858	-0.479253858	normal	0.957176847	0.156547226	normal	0.902803002	-0.35737246	normal	0.585003091	-0.22432588	normal	--	--	--	--	--	--	--	--	Transmembrane and coiled-coil domain-containing protein 6 GN=TMCO6 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane and coiled-coil domain-containing protein 6 isoform X1 [Camelus bactrianus] 
ENSG00000113140(SPARC)	--	0.032065164	2	0.127283528	8	0.158730264	4	4.5218729	295	6.51037949	350	4.18191748	202	0	6.365712466	up	0	5.187962332	up	0	5.19919786	up	8.53E-22	5.896197678	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	--	--	[W]	Extracellular structures	Secreted protein acidic and rich in cysteine Ca binding region;; Follistatin/Osteonectin-like EGF domain;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	SPARC (Precursor) GN=SPARC OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	SPARC precursor [Camelus ferus]
ENSG00000113141(IK)	--	44.04622752	1938	41.36224457	1955	46.41932974	2039	49.872105	2223	50.11114802	2090	46.54063717	2054	0.977934048	0.166983442	normal	0.985128741	0.074851772	normal	0.987096406	0.002281278	normal	0.728393947	0.080737808	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K13109|0|hsa:3550|IK, CSA2, RED; IK cytokine, down-regulator of HLA II; K13109 IK cytokine (A)"	--	[T]	Signal transduction mechanisms	RED-like protein N-terminal region;; RED-like protein C-terminal region	Protein Red GN=IK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein Red [Capra hircus]
ENSG00000113161(HMGCR)	--	25.85399858	1923	32.185159	2463	30.55949062	2310	16.93790451	1290	17.86473657	1322	27.43670159	2063	0.050085913	-0.606224242	normal	8.82E-06	-0.918338327	normal	0.978067932	-0.171321719	normal	0.080126321	-0.538072929	normal	[I]	Lipid transport and metabolism	Molecular Function: hydroxymethylglutaryl-CoA reductase (NADPH) activity (GO:0004420);; Biological Process: coenzyme A metabolic process (GO:0015936);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00021|0|hsa:3156|HMGCR, LDLCQ3; 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34); K00021 hydroxymethylglutaryl-CoA reductase (NADPH) [EC:1.1.1.34] (A)"	Terpenoid backbone biosynthesis (ko00900);; AMPK signaling pathway (ko04152);; Bile secretion (ko04976)	[I]	Lipid transport and metabolism	Hydroxymethylglutaryl-coenzyme A reductase;; Sterol-sensing domain of SREBP cleavage-activation;; Patched family	3-hydroxy-3-methylglutaryl-coenzyme A reductase GN=HMGCR OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: 3-hydroxy-3-methylglutaryl-coenzyme A reductase isoform 1 [Odobenus rosmarus divergens]
ENSG00000113163(COL4A3BP)	--	12.291787	780	15.413238	931	12.85011	843	18.85871885	1217	15.973423	1071	24.46744	1546	0.052572829	0.609981803	normal	0.96321116	0.180405457	normal	5.33E-05	0.865480578	normal	0.030348921	0.565509262	normal	--	--	Molecular Function: lipid binding (GO:0008289);; 	K08283|0|ggo:101137213|COL4A3BP; collagen type IV alpha-3-binding protein; K08283 collagen type IV alpha-3-binding protein (A)	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	START domain;; PH domain;; Pleckstrin homology domain	Collagen type IV alpha-3-binding protein GN=COL4A3BP OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	hypothetical protein PANDA_005467 [Ailuropoda melanoleuca]
ENSG00000113194(FAF2)	--	25.4335187	2038	25.70240254	2060	22.9845231	1828	27.1009565	2163	29.404285	2340	26.910987	2162	0.986539935	0.055007096	normal	0.97914842	0.162325769	normal	0.962156042	0.233631092	normal	0.458762106	0.148197523	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K18726|0|hsa:23197|FAF2, ETEA, UBXD8, UBXN3B; Fas associated factor family member 2; K18726 FAS-associated factor 2 (A)"	--	[T]	Signal transduction mechanisms	UBA-like domain;; UBX domain	FAS-associated factor 2 GN=FAF2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: FAS-associated factor 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000113196(HAND1)	--	0	0	0	0	0.0691469	1	0	0	0.0690484	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09071|2.74844e-96|hsa:9421|HAND1, Hxt, Thing1, bHLHa27, eHand; heart and neural crest derivatives expressed 1; K09071 heart-and neural crest derivatives-expressed protein 1 (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Heart- and neural crest derivatives-expressed protein 1 GN=HAND1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: heart- and neural crest derivatives-expressed protein 1 isoform X2 [Mustela putorius furo] 
ENSG00000113205(PCDHB3)	--	0.21397871	12	0.28402982	16	0.089425172	4	0.271793952	15	0.07009795	3	0.210754157	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56132|PCDHB3, PCDH-BETA3; protocadherin beta 3; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-3 (Precursor) GN=PCDHB3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin beta-3 [Pteropus alecto]
ENSG00000113209(PCDHB5)	--	2.58237434	149	4.696084	222	3.0614394	175	2.569274463	133	2.573982	162	2.446527065	119	0.955271502	-0.192614595	normal	0.709981923	-0.472210076	normal	0.593979407	-0.558792261	normal	0.207876687	-0.42082233	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:26167|PCDHB5, PCDH-BETA5; protocadherin beta 5; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-5 (Precursor) GN=PCDHB5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protocadherin Fat 3-like [Balaenoptera acutorostrata scammoni]
ENSG00000113211(PCDHB6)	--	1.167673271	66	0.760003036	43	1.129200596	64	0.955216002	54	1.433237425	81	0.960582024	55	0.960907107	-0.312286335	normal	0.393892754	0.869539093	normal	0.96964561	-0.221285736	normal	0.886763815	0.114677864	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56130|PCDHB6, PCDH-BETA6; protocadherin beta 6; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-6 (Precursor) GN=PCDHB6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin beta-6 [Equus caballus]
ENSG00000113212(PCDHB7)	--	0.0646059	4	0.0322493	2	0.127029	7	0	0	0.046717	2	0.0318672	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56129|PCDHB7, PCDH-BETA7; protocadherin beta 7; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-7 (Precursor) GN=PCDHB7 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin beta-7 [Equus caballus]
ENSG00000113231(PDE8B)	--	2.77304107	269	2.958657728	306	3.421738816	278	3.225539106	268	4.145128942	367	4.556517334	306	0.966814396	-0.035999436	normal	0.930898907	0.239738756	normal	0.959924802	0.129483728	normal	0.725513278	0.120874331	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K18437|0|mcf:102138645|PDE8B; phosphodiesterase 8B; K18437 high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; PDE8 phosphodiesterase;; PAS domain;; Response regulator receiver domain;; PAS fold;; PAS fold;; PAS fold;; PAS domain	"High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B GN=PDE8B OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1 [Pteropus alecto]"
ENSG00000113240(CLK4)	--	4.045889622	157	5.767879538	235	5.999898015	212	3.555321573	143	5.778517203	224	5.072213621	200	0.958498112	-0.163900175	normal	0.962563014	-0.089995308	normal	0.963726922	-0.091682252	normal	0.831092618	-0.111264106	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08823|0|ptr:471811|CLK4; CDC-like kinase 4; K08823 CDC-like kinase [EC:2.7.12.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Dual specificity protein kinase CLK4 GN=CLK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual specificity protein kinase CLK4 isoform X2 [Mustela putorius furo] 
ENSG00000113248(PCDHB15)	--	0.384747898	31	0.65250468	39	0.518017645	32	0.546949879	20	0.478663447	33	0.332564592	21	0.96133268	-0.624280445	normal	0.977005659	-0.251806665	normal	0.963507018	-0.581803368	normal	0.508045851	-0.483987786	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56121|PCDHB15, PCDH-BETA15; protocadherin beta 15; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-15 (Precursor) GN=PCDHB15 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protocadherin beta-15 isoform X2 [Equus przewalskii]
ENSG00000113249(HAVCR1)	--	36.1901315	2960	38.33701374	3212	43.53425799	3279	78.2626965	7305	82.16105002	6434	101.32093	8457	1.02E-12	1.272020806	up	7.70E-07	0.980485008	normal	1.12E-14	1.358194025	up	3.25E-11	1.211047468	up	--	--	--	--	--	--	--	Immunoglobulin V-set domain	Hepatitis A virus cellular receptor 1 (Precursor) GN=HAVCR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: hepatitis A virus cellular receptor 1 [Galeopterus variegatus]
ENSG00000113263(ITK)	--	0	0	0	0	0.024235235	1	0.048936536	4	0.011929133	0	0.097714092	8	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K07363|0|hsa:3702|ITK, EMT, LPFS1, LYK, PSCTK2; IL2-inducible T-cell kinase (EC:2.7.10.2); K07363 IL2-inducible T-cell kinase [EC:2.7.10.2] (A)"	Chemokine signaling pathway (ko04062);; T cell receptor signaling pathway (ko04660);; Leukocyte transendothelial migration (ko04670)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; BTK motif;; SH3 domain;; PH domain;; Variant SH3 domain;; Variant SH3 domain;; Bacterial SH3 domain	Tyrosine-protein kinase ITK/TSK GN=ITK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase ITK/TSK [Ceratotherium simum simum]
ENSG00000113269(RNF130)	--	29.375645	1056	31.160134	1100	24.1108605	859	28.7230151	1024	29.364436	1044	26.885719	958	0.977856904	-0.075115389	normal	0.976302589	-0.096671924	normal	0.968252644	0.148827866	normal	0.964158026	-0.016503483	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K15701|0|ptr:741135|RNF130; ring finger protein 130; K15701 E3 ubiquitin-protein ligase RNF130 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; PA domain;; RING-H2 zinc finger;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF130 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF130 [Odobenus rosmarus divergens]
ENSG00000113272(THG1L)	--	8.52804	527	7.96318	498	7.65002	472	8.47745	526	9.85021	603	8.60904	532	0.971767482	-0.03347474	normal	0.925787833	0.253884173	normal	0.957475205	0.163853184	normal	0.632321368	0.128759867	normal	[S]	Function unknown	Molecular Function: magnesium ion binding (GO:0000287);; Biological Process: tRNA modification (GO:0006400);; Molecular Function: tRNA guanylyltransferase activity (GO:0008193);; 	"K10761|0|hsa:54974|THG1L, ICF45, IHG-1; tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) (EC:2.7.7.79); K10761 tRNA(His) guanylyltransferase [EC:2.7.7.79] (A)"	--	[S]	Function unknown	Thg1 C terminal domain;; tRNAHis guanylyltransferase	Probable tRNA(His) guanylyltransferase GN=THG1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: probable tRNA(His) guanylyltransferase [Galeopterus variegatus]
ENSG00000113273(ARSB)	--	9.627355	746	10.94018622	805	9.505376252	722	7.889558651	616	8.027119	559	9.964984	700	0.886879054	-0.306381844	normal	0.213097366	-0.546328077	normal	0.974496845	-0.052822984	normal	0.120612075	-0.298702572	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K01135|0|hsa:411|ARSB, ASB, G4S, MPS6; arylsulfatase B (EC:3.1.6.12); K01135 arylsulfatase B [EC:3.1.6.12] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	[R]	General function prediction only	Sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	Arylsulfatase B (Precursor) GN=ARSB OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: arylsulfatase B [Orcinus orca]
ENSG00000113282(CLINT1)	--	37.51934503	2365	42.46262928	2725	40.88491086	2458	42.841003	2711	43.536187	2729	43.500564	2679	0.980824722	0.166051856	normal	0.989132184	-0.01929969	normal	0.985660513	0.115849932	normal	0.718422964	0.083901265	normal	--	--	Molecular Function: phospholipid binding (GO:0005543);; 	--	--	[F]	Nucleotide transport and metabolism	ENTH domain;; ANTH domain	Clathrin interactor 1 GN=CLINT1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: clathrin interactor 1 isoform X1 [Felis catus]
ENSG00000113296(THBS4)	--	0	0	0.04251497	3	0.014021661	0	0.028739394	2	0	0	0.028651785	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: cell adhesion (GO:0007155);; 	"K04659|0|hsa:7060|THBS4, TSP4; thrombospondin 4; K04659 thrombospondin 2/3/4/5 (A)"	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Malaria (ko05144)	--	--	Thrombospondin C-terminal region;; Thrombospondin type 3 repeat;; Cartilage oligomeric matrix protein;; Calcium-binding EGF domain;; Complement Clr-like EGF-like	Thrombospondin-4 (Precursor) GN=THBS4 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: thrombospondin-4 [Odobenus rosmarus divergens]
ENSG00000113300(CNOT6)	--	14.05012856	1148	12.70122537	1035	15.6915044	1163	18.53977431	1389	15.84880992	1265	16.88765008	1232	0.947112806	0.243794718	normal	0.932450243	0.267725719	normal	0.979660198	0.074765249	normal	0.308411638	0.194412006	normal	[A]	RNA processing and modification	Molecular Function: protein binding (GO:0005515);; 	"K12603|0|ptr:462338|CNOT6; CCR4-NOT transcription complex, subunit 6; K12603 CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] (A)"	RNA degradation (ko03018)	[K]	Transcription	Endonuclease/Exonuclease/phosphatase family;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat	CCR4-NOT transcription complex subunit 6 GN=CNOT6 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 6 [Dasypus novemcinctus]
ENSG00000113302(IL12B)	--	0	0	0.0194121	1	0	0	0	0	0.0757309	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05425|0|hsa:3593|IL12B, CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2; interleukin 12B; K05425 interleukin 12B (A)"	Cytokine-cytokine receptor interaction (ko04060);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Jak-STAT signaling pathway (ko04630);; Type I diabetes mellitus (ko04940);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Proteoglycans in cancer (ko05205);; Inflammatory bowel disease (IBD) (ko05321);; Allograft rejection (ko05330)	--	--	Cytokine interleukin-12p40 C-terminus;; Fibronectin type III domain	Interleukin-12 subunit beta (Precursor) GN=IL12B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-12 subunit beta [Galeopterus variegatus]
ENSG00000113312(TTC1)	--	31.2399	927	32.34049	968	33.493025	988	41.445567	1233	42.164805	1228	35.766554	1043	0.775292965	0.380151403	normal	0.884514739	0.321358394	normal	0.977940119	0.069760833	normal	0.146402093	0.259855068	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 1 GN=TTC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 1 [Galeopterus variegatus]
ENSG00000113318(MSH3)	--	7.19582	571	7.67225	605	8.46213	659	8.49153	674	8.84378	700	8.21997	651	0.947774118	0.207910228	normal	0.954124106	0.188554749	normal	0.974454658	-0.025852673	normal	0.63570135	0.121076888	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	"K08736|0|hsa:4437|MSH3, DUP, MRP1; mutS homolog 3; K08736 DNA mismatch repair protein MSH3 (A)"	Mismatch repair (ko03430);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210)	[L]	"Replication, recombination and repair"	MutS domain V;; MutS domain III;; MutS domain II;; MutS domain I;; MutS family domain IV	DNA mismatch repair protein Msh3 GN=MSH3 OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: DNA mismatch repair protein Msh3 [Galeopterus variegatus]
ENSG00000113319(RASGRF2)	--	2.43239002	241	2.095673696	194	1.754513008	192	7.185880789	769	9.061086608	989	6.452635407	637	3.33E-16	1.636957638	up	0	2.319588243	up	1.11E-16	1.714039977	up	1.92E-08	1.911805646	up	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K12326|0|hsa:5924|RASGRF2, GRF2, RAS-GRF2; Ras protein-specific guanine nucleotide-releasing factor 2; K12326 Ras-specific guanine nucleotide-releasing factor 2 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	RasGEF domain;; RhoGEF domain;; PH domain;; RasGEF N-terminal motif	Ras-specific guanine nucleotide-releasing factor 2 GN=RASGRF2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ras-specific guanine nucleotide-releasing factor 2 [Balaenoptera acutorostrata scammoni]
ENSG00000113327(GABRG2)	--	0	0	0	0	0	0	0.342057	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05186|0|mcf:102141724|GABRG2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; K05186 gmma-aminobutyric acid receptor subunit gamma (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Gamma-aminobutyric acid receptor subunit gamma-2 (Precursor) GN=GABRG2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit gamma-2 isoform X1 [Vicugna pacos]
ENSG00000113328(CCNG1)	--	59.70187469	2153	59.23051693	2095	63.1718252	2233	63.25899383	2365	57.4102059	2090	71.6451131	2600	0.98504503	0.104588374	normal	0.986797055	-0.024855896	normal	0.972329721	0.211104317	normal	0.645954263	0.101563265	normal	--	--	--	K10145|0|ptr:462243|CCNG1; cyclin G1; K10145 cyclin G1 (A)	p53 signaling pathway (ko04115);; MicroRNAs in cancer (ko05206)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-G1 GN=CCNG1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-G1 isoform X1 [Mustela putorius furo] 
ENSG00000113356(POLR3G)	--	9.429222073	390	7.028488381	273	10.16723078	414	9.968542515	357	8.185358066	288	3.389764264	155	0.956185194	-0.157732523	normal	0.965209364	0.055442274	normal	5.30E-10	-1.416851506	down	0.393709563	-0.451907771	normal	--	--	Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription from RNA polymerase III promoter (GO:0006383);; 	K03024|6.12181e-71|ptr:461759|POLR3G; polymerase (RNA) III (DNA directed) polypeptide G (32kD); K03024 DNA-directed RNA polymerase III subunit RPC7 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	--	--	DNA-directed RNA polymerase III subunit Rpc31	DNA-directed RNA polymerase III subunit RPC7 GN=POLR3G OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC7 isoform X3 [Camelus bactrianus]
ENSG00000113360(DROSHA)	--	16.24424566	1513	21.45404268	1680	21.69374126	1836	21.41591127	1980	18.38718221	1590	21.47765261	1912	0.849175942	0.356938528	normal	0.981345533	-0.100767769	normal	0.985592871	0.050184514	normal	0.640061201	0.103270319	normal	[K]	Transcription	Molecular Function: ribonuclease III activity (GO:0004525);; Biological Process: RNA processing (GO:0006396);; 	"K03685|0|pps:100995985|DROSHA; drosha, ribonuclease type III; K03685 ribonuclease III [EC:3.1.26.3] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; Proteoglycans in cancer (ko05205)	[A]	RNA processing and modification	Ribonuclease-III-like;; Ribonuclease III domain;; Double-stranded RNA binding motif	Ribonuclease 3 GN=DROSHA OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribonuclease 3 isoformX1 [Equus caballus] 
ENSG00000113361(CDH6)	--	0.6697976	43	0.344512337	30	0.836727	59	5.028306	579	8.58196	941	6.183468	643	0	3.674067748	up	0	4.881629769	up	0	3.404729708	up	1.72E-14	4.014715682	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06798|0|hsa:1004|CDH6, CAD6, KCAD; cadherin 6, type 2, K-cadherin (fetal kidney); K06798 cadherin 6, type 2, K-cadherin (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-6 (Precursor) GN=CDH6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cadherin-6 [Ailuropoda melanoleuca] 
ENSG00000113368(LMNB1)	--	29.26828638	1519	32.29558131	1731	32.61741669	1672	47.74602783	2367	48.81560839	2419	37.81864848	1890	0.048422507	0.608608777	normal	0.556961787	0.46103632	normal	0.975453087	0.168376623	normal	0.00905313	0.417988773	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	K07611|0|ggo:101147221|LMNB1; lamin-B1 isoform 1; K07611 lamin B (A)	--	[DY]	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	Intermediate filament protein;; Lamin Tail Domain	Lamin-B1 (Precursor) GN=LMNB1 OS=Homo sapiens (Human) PE=1 SV=2	DY	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	PREDICTED: lamin-B1 [Ovis aries]
ENSG00000113369(ARRDC3)	--	15.8118	1042	12.2979	804	11.6728	750	22.789	1510	21.0813	1386	27.6209	1821	0.316295667	0.503740867	normal	0.001555	0.763127276	normal	1.00E-11	1.269780283	up	0.000165535	0.840610427	normal	--	--	--	--	--	[R]	General function prediction only	"Arrestin (or S-antigen), N-terminal domain;; Arrestin (or S-antigen), C-terminal domain"	Arrestin domain-containing protein 3 GN=ARRDC3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	arrestin domain-containing protein 3 [Camelus ferus]
ENSG00000113384(GOLPH3)	--	37.8891	1452	39.3697	1523	34.8002	1332	40.2407	1554	40.8892	1571	45.508	1749	0.982635696	0.067044208	normal	0.983820008	0.023317884	normal	0.783749593	0.384262911	normal	0.427630066	0.157376194	normal	--	--	Molecular Function: phosphatidylinositol-4-phosphate binding (GO:0070273);; 	K15620|0|ptr:461946|GOLPH3; golgi phosphoprotein 3 (coat-protein); K15620 golgi phosphoprotein 3 (A)	Transcriptional misregulation in cancer (ko05202)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Golgi phosphoprotein 3 (GPP34)	Golgi phosphoprotein 3 GN=GOLPH3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi phosphoprotein 3 [Trichechus manatus latirostris]
ENSG00000113387(SUB1)	--	78.395728	1839	64.0343927	1688	84.589979	1870	104.87239	2527	107.0115311	2546	93.09390701	2274	0.677243506	0.427366221	normal	0.126362499	0.571071652	normal	0.945590317	0.273701519	normal	0.0046431	0.423650467	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: transcription coactivator activity (GO:0003713);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Transcriptional Coactivator p15 (PC4)	Activated RNA polymerase II transcriptional coactivator p15 GN=SUB1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	activated RNA polymerase II transcriptional coactivator p15 isoform 2 [Camelus ferus]
ENSG00000113389(NPR3)	--	6.59174177	725	5.7875089	592	6.01238277	650	4.799985784	479	5.306190634	499	3.575804737	319	0.05264711	-0.627139654	normal	0.917725227	-0.267239301	normal	2.98E-06	-1.031674977	down	0.004606338	-0.622999715	normal	--	--	--	"K12325|0|hsa:4883|NPR3, ANP-C, ANPR-C, ANPRC, C5orf23, GUCY2B, NPR-C, NPRC; natriuretic peptide receptor 3; K12325 atrial natriuretic peptide clearance receptor (A)"	--	[T]	Signal transduction mechanisms	Receptor family ligand binding region	Atrial natriuretic peptide receptor 3 (Precursor) GN=NPR3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: atrial natriuretic peptide receptor 3 isoform X1 [Galeopterus variegatus]
ENSG00000113391(FAM172A)	--	11.4450175	542	9.504118604	474	8.33314078	468	9.44887915	494	9.880480585	463	6.280135132	380	0.95758473	-0.164126487	normal	0.969020467	-0.05512347	normal	0.885707529	-0.307695046	normal	0.510321905	-0.172544805	normal	--	--	--	--	--	[S]	Function unknown	Arb2 domain	Protein FAM172A (Precursor) GN=FAM172A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM172A isoform X2 [Ursus maritimus]
ENSG00000113396(SLC27A6)	--	0.4335381	19	0.513413	22	0.298497	10	0	0	0.0172955	0	0	0	--	--	--	0.000895898	-3.96867203	down	--	--	--	--	--	--	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K08749|0|hsa:28965|SLC27A6, ACSVL2, FACVL2, FATP6, VLCS-H1; solute carrier family 27 (fatty acid transporter), member 6; K08749 solute carrier family 27 (fatty acid transporter), member 6 (A)"	PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	Long-chain fatty acid transport protein 6 GN=SLC27A6 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: long-chain fatty acid transport protein 6 [Ceratotherium simum simum]
ENSG00000113407(TARS)	--	78.76067885	4344	85.71408961	4786	80.63930343	4457	75.6993456	4207	75.90895101	4164	88.42148416	4843	0.99160598	-0.077036859	normal	0.980189183	-0.22220154	normal	0.990973764	0.111500297	normal	0.811647742	-0.061007074	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	K01868|0|mcf:101866943|uncharacterized LOC101866943; K01868 threonyl-tRNA synthetase [EC:6.1.1.3] (A)	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain;; Threonyl and Alanyl tRNA synthetase second additional domain;; TGS domain"	"Threonine--tRNA ligase, cytoplasmic GN=TARS OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: threonine--tRNA ligase, cytoplasmic isoform X2 [Bison bison bison]"
ENSG00000113430(IRX4)	--	0	0	0.027261066	1	0	0	0	0	0.133568053	0	0.07669015	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Iroquois-class homeodomain protein IRX-4 GN=IRX4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: iroquois-class homeodomain protein IRX-4 [Leptonychotes weddellii]
ENSG00000113441(LNPEP)	--	9.08972	1655	10.99794	1985	9.66328	1724	12.07766	2200	9.83681	1782	12.16012	2210	0.809584417	0.379533569	normal	0.974707952	-0.17692588	normal	0.868600827	0.349723537	normal	0.353497208	0.18568965	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	"K01257|0|hsa:4012|LNPEP, CAP, IRAP, P-LAP, PLAP; leucyl/cystinyl aminopeptidase (EC:3.4.11.3); K01257 cystinyl aminopeptidase [EC:3.4.11.3] (A)"	Renin-angiotensin system (ko04614)	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	"Leucyl-cystinyl aminopeptidase, pregnancy serum form GN=LNPEP OS=Homo sapiens (Human) PE=1 SV=3"	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: leucyl-cystinyl aminopeptidase [Galeopterus variegatus]
ENSG00000113448(PDE4D)	--	39.20107291	4467	41.50026816	4841	37.7562805	4176	32.67842166	3589	38.05831059	4370	33.18807017	3872	0.913946839	-0.346423348	normal	0.987165235	-0.169042761	normal	0.989637087	-0.117290078	normal	0.253175651	-0.209768911	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13293|0|mcf:102137767|PDE4D; phosphodiesterase 4D, cAMP-specific; K13293 cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; cAMP signaling pathway (ko04024);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase	"cAMP-specific 3',5'-cyclic phosphodiesterase 4D GN=PDE4D OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4D isoform X1 [Leptonychotes weddellii]"
ENSG00000113456(RAD1)	--	11.8461135	611	11.9084172	609	10.80282208	580	11.794983	619	10.42706914	572	9.7317555	513	0.97386749	-0.012035167	normal	0.967002304	-0.111567707	normal	0.953383221	-0.18487262	normal	0.718422964	-0.100909993	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	K02830|0|pps:100983809|RAD1; RAD1 checkpoint DNA exonuclease; K02830 cell cycle checkpoint protein [EC:3.1.11.2] (A)	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Repair protein Rad1/Rec1/Rad17	Cell cycle checkpoint protein RAD1 GN=RAD1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: cell cycle checkpoint protein RAD1 isoform X1 [Equus caballus] 
ENSG00000113460(BRIX1)	--	21.5846	740	20.5704	708	24.4914	835	20.4167	706	20.1277	692	16.8012	576	0.971453738	-0.09847998	normal	0.973594539	-0.054286587	normal	0.204386671	-0.54280818	normal	0.25830777	-0.231288764	normal	--	--	--	"K14820|0|hsa:55299|BRIX1, BRIX, BXDC2; BRX1, biogenesis of ribosomes, homolog (S. cerevisiae); K14820 ribosome biogenesis protein BRX1 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Brix domain	Ribosome biogenesis protein BRX1 homolog GN=BRIX1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosome biogenesis protein BRX1 homolog [Felis catus] 
ENSG00000113494(PRLR)	--	0.081303877	13	0.23426841	14	0.18218366	7	0.148251773	4	0.187287705	5	0.101832942	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05081|0|ptr:461925|PRLR; prolactin receptor; K05081 prolactin receptor (A)	Cytokine-cytokine receptor interaction (ko04060);; Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917)	--	--	"Erythropoietin receptor, ligand binding;; Interleukin-6 receptor alpha chain, binding;; Fibronectin type III domain;; Growth hormone receptor binding"	Prolactin receptor (Precursor) GN=PRLR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: prolactin receptor isoform X1 [Galeopterus variegatus]
ENSG00000113504(SLC12A7)	--	12.46955646	1307	11.30867473	1199	11.80733153	1267	14.9762656	1576	15.12633909	1585	16.03090254	1693	0.952386703	0.238920074	normal	0.794973232	0.380805674	normal	0.708957574	0.409449804	normal	0.032487436	0.342521094	normal	[E]	Amino acid transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13627|0|hsa:10723|SLC12A7, KCC4; solute carrier family 12 (potassium/chloride transporter), member 7; K13627 solute carrier family 12 (potassium/chloride transporter), member 7 (A)"	Collecting duct acid secretion (ko04966)	[P]	Inorganic ion transport and metabolism	Amino acid permease;; Amino acid permease	Solute carrier family 12 member 7 GN=SLC12A7 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 12 member 7 isoform X1 [Eptesicus fuscus]
ENSG00000113522(RAD50)	--	27.81160989	3811	30.65523012	4409	29.24093743	4174	28.4254042	3997	26.00404214	3724	29.01057907	4143	0.99178196	0.037900781	normal	0.968105173	-0.264925951	normal	0.992327336	-0.019039298	normal	0.721808438	-0.084169337	normal	[L]	"Replication, recombination and repair"	--	"K10866|0|hsa:10111|RAD50, NBSLD, RAD502, hRad50; RAD50 homolog (S. cerevisiae); K10866 DNA repair protein RAD50 [EC:3.6.-.-] (A)"	Homologous recombination (ko03440);; Non-homologous end-joining (ko03450)	[L]	"Replication, recombination and repair"	"AAA domain;; Rad50 zinc hook motif;; Putative exonuclease SbcCD, C subunit;; AAA domain"	DNA repair protein RAD50 GN=RAD50 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein RAD50 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000113532(ST8SIA4)	--	4.951461966	251	3.187700189	142	2.329529141	143	2.089519	139	4.040193606	221	2.590897727	147	0.006238682	-0.87611708	normal	0.351539886	0.611469878	normal	0.967718824	0.031184291	normal	0.905275811	-0.101465301	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K06614|0|pon:100445679|ST8SIA4; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4; K06614 alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8D) [EC:2.4.99.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase GN=ST8SIA4 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase [Tupaia chinensis] "
ENSG00000113552(GNPDA1)	--	35.82330978	1421	53.92776006	2157	38.34771818	1496	41.15774206	1625	37.2323418	1459	65.89282263	2552	0.973896844	0.162536478	normal	0.093253934	-0.584970768	normal	0.000870372	0.76163036	normal	0.85721208	0.131302533	normal	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; 	K02564|0|pps:100975855|GNPDA1; glucosamine-6-phosphate deaminase 1; K02564 glucosamine-6-phosphate deaminase [EC:3.5.99.6] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	Glucosamine-6-phosphate isomerase 1 GN=GNPDA1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	glucosamine-6-phosphate isomerase 1 [Camelus ferus]
ENSG00000113555(PCDH12)	--	0.22618	33	0.642331	38	0.133672	19	0.1892982	13	0.213638	31	0.19054	28	0.601198333	-1.276960901	normal	0.97552968	-0.301834527	normal	0.974516355	0.517053995	normal	0.682986601	-0.34200569	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16499|0|hsa:51294|PCDH12, VE-cadherin-2, VECAD2; protocadherin 12; K16499 protocadherin delta 2 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin-12 (Precursor) GN=PCDH12 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin-12 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000113558(SKP1)	--	330.9393283	6598	330.4542648	6504	345.9626903	6598	407.266906	8566	407.0477649	8131	367.5933832	7025	0.944486883	0.34568982	normal	0.968963981	0.300616353	normal	0.994072098	0.082159753	normal	0.183394884	0.246286798	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; 	K03094|1.28015e-88|lcm:102350053|SKP1; S-phase kinase-associated protein 1; K03094 S-phase kinase-associated protein 1 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Wnt signaling pathway (ko04310);; TGF-beta signaling pathway (ko04350);; Herpes simplex infection (ko05168)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Skp1 family, dimerisation domain;; Skp1 family, tetramerisation domain"	S-phase kinase-associated protein 1 GN=SKP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: S-phase kinase-associated protein 1-like [Bubalus bubalis]
ENSG00000113569(NUP155)	--	14.93338236	1593	14.73765318	1605	16.03656224	1710	14.68447641	1691	15.28042153	1644	12.08372238	1386	0.984059241	0.05524641	normal	0.984439592	0.013198157	normal	0.906460548	-0.311054362	normal	0.745868926	-0.077666396	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K14312|0|ptr:461913|NUP155; nucleoporin 155kDa; K14312 nuclear pore complex protein Nup155 (A)	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Non-repetitive/WGA-negative nucleoporin C-terminal;; Nup133 N terminal like	Nuclear pore complex protein Nup155 GN=NUP155 OS=Homo sapiens (Human) PE=1 SV=1	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup155 [Galeopterus variegatus]
ENSG00000113578(FGF1)	--	0	0	0.120679604	8	0.060272539	3	0.207663435	13	0.202547701	4	0.045166566	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K18496|1.64681e-112|ptr:462158|FGF1; fibroblast growth factor 1 (acidic); K18496 fibroblast growth factor 1 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Hippo signaling pathway (ko04390);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor;; Fascin domain	Fibroblast growth factor 1 (Precursor) GN=FGF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 1 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000113580(NR3C1)	--	32.83367504	3504	38.44014484	4050	33.21782848	3464	37.37060564	3992	39.06492101	4037	34.98108479	3654	0.986337068	0.157212068	normal	0.991871062	-0.026055134	normal	0.990540998	0.06871705	normal	0.800513651	0.062942268	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: glucocorticoid receptor activity (GO:0004883);; Molecular Function: steroid binding (GO:0005496);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: glucocorticoid receptor signaling pathway (GO:0042921);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Biological Process: glucocorticoid mediated signaling pathway (GO:0043402);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K05771|0|hsa:2908|NR3C1, GCCR, GCR, GCRST, GR, GRL; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); K05771 glucocorticoid receptor (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	"Glucocorticoid receptor;; Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Glucocorticoid receptor GN=NR3C1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: glucocorticoid receptor isoform X1 [Bos taurus] 
ENSG00000113583(C5orf15)	--	42.4515	1353	43.2737	1362	40.2158	1253	53.6599	1736	42.5498	1360	45.2382	1447	0.886100723	0.328442874	normal	0.982434468	-0.023520475	normal	0.964343374	0.199163205	normal	0.368606009	0.173246537	normal	--	--	--	--	--	--	--	--	Keratinocyte-associated transmembrane protein 2 (Precursor) GN=KCT2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: keratinocyte-associated transmembrane protein 2 isoform X1 [Ursus maritimus]
ENSG00000113593(PPWD1)	--	11.62904595	430	12.37953768	487	10.99642316	427	12.20737648	483	12.37096966	480	11.99941457	439	0.96142631	0.136394272	normal	0.969913838	-0.042181983	normal	0.97003479	0.031583109	normal	0.911558094	0.039348642	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein folding (GO:0006457);; 	K12736|0|pps:100982701|PPWD1; peptidylprolyl isomerase domain and WD repeat containing 1; K12736 peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD;; WD domain, G-beta repeat"	Peptidylprolyl isomerase domain and WD repeat-containing protein 1 GN=PPWD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	peptidylprolyl isomerase domain and WD repeat-containing protein 1 [Sus scrofa] 
ENSG00000113594(LIFR)	--	4.247803611	603	4.17932666	572	3.99334312	576	3.278369881	467	3.085436235	426	2.836300676	352	0.730068294	-0.398410552	normal	0.609031181	-0.44521892	normal	0.012451216	-0.71635413	normal	0.006106943	-0.514069185	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05058|0|hsa:3977|LIFR, CD118, LIF-R, SJS2, STWS, SWS; leukemia inhibitory factor receptor alpha; K05058 leukemia inhibitory factor receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630)	--	--	Fibronectin type III domain	Leukemia inhibitory factor receptor (Precursor) GN=LIFR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leukemia inhibitory factor receptor [Ailuropoda melanoleuca] 
ENSG00000113595(TRIM23)	--	5.780215001	383	5.728536476	384	6.477197	381	4.770856035	303	5.383219	327	6.771847066	397	0.819474798	-0.367198305	normal	0.92499637	-0.252164725	normal	0.968417773	0.050858796	normal	0.525184117	-0.181077927	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Cellular Component: intracellular (GO:0005622);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Molecular Function: zinc ion binding (GO:0008270);; 	K07963|0|ptr:461843|TRIM23; tripartite motif containing 23; K07963 tripartite motif-containing protein 23 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADP-ribosylation factor family;; Ras family;; Signal recognition particle receptor beta subunit;; Miro-like protein;; Gtr1/RagA G protein conserved region;; B-box zinc finger	E3 ubiquitin-protein ligase TRIM23 GN=TRIM23 OS=Homo sapiens (Human) PE=1 SV=1	OU	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 ubiquitin-protein ligase TRIM23 isoform X1 [Equus caballus] 
ENSG00000113597(TRAPPC13)	--	12.265747	421	11.8055	408	10.68979199	362	12.46850474	398	10.4343856	373	10.099968	358	0.963907078	-0.111465592	normal	0.957078522	-0.150237422	normal	0.968732391	-0.024219807	normal	0.762792806	-0.098873685	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF974)	Trafficking protein particle complex subunit 13 GN=TRAPPC13 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: trafficking protein particle complex subunit 13 isoform X1 [Oryctolagus cuniculus]
ENSG00000113615(SEC24A)	--	7.985946	731	9.510162765	779	8.6291671	747	10.45643309	946	12.25985955	1112	9.296330818	887	0.846484912	0.340505949	normal	0.393906931	0.491232976	normal	0.93975419	0.239089718	normal	0.034310759	0.362559698	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: COPII vesicle coat (GO:0030127);; 	K14007|0|ggo:101126046|SEC24A; protein transport protein Sec24A isoform 1; K14007 protein transport protein SEC24 (A)	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec23/Sec24 trunk domain;; Sec23/Sec24 helical domain;; Sec23/Sec24 beta-sandwich domain;; Sec23/Sec24 zinc finger;; Gelsolin repeat	Protein transport protein Sec24A GN=SEC24A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec24A [Ceratotherium simum simum]
ENSG00000113621(TXNDC15)	--	30.43034442	1272	36.00980104	1495	35.26565641	1347	30.410638	1325	27.20758311	1150	35.5462247	1403	0.982239494	0.028028255	normal	0.74429775	-0.39947598	normal	0.982337082	0.05041825	normal	0.634565301	-0.106393346	normal	--	--	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[S]	Function unknown	Thioredoxin	Thioredoxin domain-containing protein 15 (Precursor) GN=TXNDC15 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: thioredoxin domain-containing protein 15 [Equus caballus]
ENSG00000113638(TTC33)	--	6.6025327	340	8.347547	401	7.474833	369	8.1639953	424	7.128886	356	6.416448	326	0.904159223	0.28653588	normal	0.94742963	-0.192380987	normal	0.94969062	-0.186227732	normal	0.954684329	-0.027272839	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 33 GN=TTC33 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 33 isoform X2 [Galeopterus variegatus]
ENSG00000113643(RARS)	--	62.5804067	2363	68.79250591	2609	71.35760573	2659	66.91380539	2544	67.82890621	2543	59.35220632	2235	0.987290112	0.075599399	normal	0.98798512	-0.058357776	normal	0.9576102	-0.258739664	normal	0.728371689	-0.081073088	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: arginine-tRNA ligase activity (GO:0004814);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: arginyl-tRNA aminoacylation (GO:0006420);; 	"K01887|0|hsa:5917|RARS, ArgRS, DALRD1, HLD9; arginyl-tRNA synthetase (EC:6.1.1.19); K01887 arginyl-tRNA synthetase [EC:6.1.1.19] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class I (R);; DALR anticodon binding domain;; Arginyl tRNA synthetase N terminal domain	"Arginine--tRNA ligase, cytoplasmic GN=RARS OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: arginine--tRNA ligase, cytoplasmic [Equus caballus]"
ENSG00000113645(WWC1)	--	37.21170485	3960	36.743853	4074	42.72836393	4644	47.31975662	5198	42.13064284	4552	63.77352262	6793	0.902962545	0.361501201	normal	0.988798748	0.138579337	normal	0.275522865	0.540243128	normal	0.233064415	0.363722343	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K16685|0|hsa:23286|WWC1, HBEBP3, HBEBP36, KIBRA, MEMRYQTL, PPP1R168; WW and C2 domain containing 1; K16685 protein KIBRA (A)"	Hippo signaling pathway (ko04390)	--	--	WW domain	Protein KIBRA GN=WWC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein KIBRA isoform 1 [Ceratotherium simum simum]
ENSG00000113648(H2AFY)	--	64.617478	2724	61.8656891	2797	64.88435735	2829	72.340275	3133	71.34480742	3029	66.651392	2853	0.982083716	0.170895873	normal	0.98780128	0.093486187	normal	0.989818001	0.003894055	normal	0.696357933	0.089126492	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; Biological Process: protein metabolic process (GO:0019538);; 	K11251|0|umr:103663804|core histone macro-H2A.1; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[BK]	Chromatin structure and dynamics;; Transcription	Macro domain;; Core histone H2A/H2B/H3/H4	Core histone macro-H2A.1 GN=H2AFY OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: core histone macro-H2A.1-like isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000113649(TCERG1)	--	15.72677558	1521	17.053361	1624	16.370109	1543	18.764638	1812	19.19456	1805	15.89272	1509	0.962046757	0.221525324	normal	0.97937808	0.130904983	normal	0.983759256	-0.040396661	normal	0.624077398	0.107128885	normal	[A]	RNA processing and modification	Molecular Function: protein binding (GO:0005515);; 	K12824|0|mcc:707912|TCERG1; transcription elongation regulator 1; K12824 transcription elongation regulator 1 (A)	Spliceosome (ko03040)	[K]	Transcription	FF domain;; WW domain	Transcription elongation regulator 1 GN=TCERG1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription elongation regulator 1 isoform X1 [Galeopterus variegatus]
ENSG00000113657(DPYSL3)	--	13.836453	1527	10.706413	1173	14.04017	1548	35.067143	3804	38.45661	3965	22.11218	2437	9.60E-13	1.285138322	up	0	1.73440053	up	0.020130703	0.645902221	normal	0.000381378	1.242575397	up	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[F]	Nucleotide transport and metabolism	Amidohydrolase family;; Amidohydrolase;; Amidohydrolase;; Amidohydrolase family	Dihydropyrimidinase-related protein 3 GN=DPYSL3 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: dihydropyrimidinase-related protein 3 isoform X1 [Tupaia chinensis]
ENSG00000113658(SMAD5)	--	17.27574069	1565	18.88186368	1595	19.29089715	1602	17.56025862	1667	21.45940659	1868	17.56830878	1552	0.983711465	0.060201915	normal	0.967161602	0.206330553	normal	0.983709452	-0.053985253	normal	0.758175957	0.073952383	normal	--	--	"Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K16790|0|umr:103663799|SMAD5; SMAD family member 5; K16790 mothers against decapentaplegic homolog 5 (A)	TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain;; Interferon-regulatory factor 3	Mothers against decapentaplegic homolog 5 GN=SMAD5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"Mothers against decapentaplegic-like protein 5, partial [Bos mutus]"
ENSG00000113712(CSNK1A1)	--	65.03462899	3724	66.541815	3829	64.40722771	3657	77.50825531	4587	77.12820594	4396	87.0567273	4965	0.966478689	0.269765144	normal	0.985154289	0.177731616	normal	0.735235107	0.43268751	normal	0.079067946	0.294232021	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08957|0|umr:103664607|CSNK1A1; casein kinase 1, alpha 1; K08957 casein kinase 1, alpha [EC:2.7.11.1] (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Casein kinase I isoform alpha GN=CSNK1A1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: casein kinase I isoform alpha isoform X1 [Pantholops hodgsonii]
ENSG00000113716(HMGXB3)	--	13.404642	1582	16.99671078	2050	14.58480518	1752	14.560157	1701	18.589097	2159	20.702988	2450	0.983306777	0.073732214	normal	0.986275892	0.053274479	normal	0.468998867	0.475139143	normal	0.527901597	0.208765889	normal	--	--	--	--	--	--	--	HMG-box domain;; HMG (high mobility group) box	HMG domain-containing protein 3 GN=HMGXB3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: HMG domain-containing protein 3 [Odobenus rosmarus divergens]
ENSG00000113719(ERGIC1)	--	168.6176633	9468	140.6048895	7807	152.9207399	8600	135.1956303	7507	139.4181947	7695	125.854294	7030	0.932244737	-0.365588684	normal	0.995030942	-0.042265254	normal	0.970315429	-0.299045146	normal	0.205203664	-0.240241093	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endoplasmic reticulum vesicle transporter;; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)	Endoplasmic reticulum-Golgi intermediate compartment protein 1 GN=HT034 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: endoplasmic reticulum-Golgi intermediate compartment protein 1 [Odobenus rosmarus divergens]
ENSG00000113721(PDGFRB)	--	0.035127128	4	0.017385692	2	0.017064769	1	0.016393834	2	0.017090126	1	0.135289627	3	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05089|0|hsa:5159|PDGFRB, CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1; platelet-derived growth factor receptor, beta polypeptide (EC:2.7.10.1); K05089 platelet-derived growth factor receptor beta [EC:2.7.10.1] (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Platelet-derived growth factor receptor beta (Precursor) GN=PDGFRB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: platelet-derived growth factor receptor beta isoform X2 [Equus przewalskii]
ENSG00000113722(CDX1)	--	0	0	0.038119193	1	0.0299097	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: multicellular organismal development (GO:0007275);; "	K09312|1.02982e-92|hsa:1044|CDX1; caudal type homeobox 1; K09312 homeobox protein CDX (A)	--	[K]	Transcription	Caudal like protein activation region;; Homeobox domain	Homeobox protein CDX-1 GN=CDX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein CDX-1 [Orcinus orca] 
ENSG00000113732(ATP6V0E1)	--	138.499883	2543	145.994489	2654	140.14093	2488	186.4604722	3497	163.16174	2980	199.2931	3689	0.707476373	0.428532475	normal	0.984064192	0.145639054	normal	0.151259987	0.559670732	normal	0.013034092	0.382447203	normal	--	--	--	"K02153|8.49314e-52|ptr:740323|ATP6V0E1, ATP6V0E; ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1; K02153 V-type H+-transporting ATPase subunit e (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase subunit H	V-type proton ATPase subunit e 1 GN=ATP6V0E1 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	RecName: Full=V-type proton ATPase subunit e 1; Short=V-ATPase subunit e 1; AltName: Full=V-ATPase 9.2 kDa membrane accessory protein; AltName: Full=V-ATPase M9.2 subunit; AltName: Full=Vacuolar proton pump subunit e 1 [Canis lupus familiaris] 
ENSG00000113734(BNIP1)	--	9.522520369	188	10.47569947	207	9.901781065	190	9.043456177	181	12.81376857	249	9.525161249	189	0.96451347	-0.084868273	normal	0.933226135	0.243464777	normal	0.966985216	-0.015778705	normal	0.901973769	0.060501756	normal	--	--	--	K08497|2.34899e-144|ptr:740480|BNIP1; BCL2/adenovirus E1B 19kDa interacting protein 1; K08497 protein transport protein SEC20 (A)	SNARE interactions in vesicular transport (ko04130)	--	--	Sec20	Vesicle transport protein SEC20 GN=BNIP1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle transport protein SEC20 isoform X2 [Equus przewalskii]
ENSG00000113739(STC2)	--	48.92743	4083	42.52797	3647	35.44939	2991	30.08912	2580	19.014815	1668	51.00146	4368	0.006172596	-0.692759673	normal	9.53E-10	-1.149294013	down	0.238700362	0.537827176	normal	0.623093513	-0.335357493	normal	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Stanniocalcin family	Stanniocalcin-2 (Precursor) GN=STC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: stanniocalcin-2 [Odobenus rosmarus divergens]
ENSG00000113742(CPEB4)	--	12.43602558	1066	12.63359788	1364	13.59400772	1047	9.910580682	906	11.17388839	1127	13.26948564	1439	0.929206761	-0.265041807	normal	0.914063309	-0.296420505	normal	0.547735294	0.449957087	normal	0.971851655	-0.022187065	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K02602|0|pps:100984532|CPEB4; cytoplasmic polyadenylation element binding protein 4; K02602 cytoplasmic polyadenylation element-binding protein (A)	Oocyte meiosis (ko04114);; Dorso-ventral axis formation (ko04320);; Progesterone-mediated oocyte maturation (ko04914)	[J]	"Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Cytoplasmic polyadenylation element-binding protein 4 GN=CPEB4 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: cytoplasmic polyadenylation element-binding protein 4 isoform 1 [Trichechus manatus latirostris]
ENSG00000113749(HRH2)	--	0.920292843	59	1.6910598	85	0.976972834	61	0.277714445	15	0.584527452	30	0.32253351	17	0.000463291	-1.901161956	down	0.001110201	-1.477715734	down	0.001220024	-1.763509079	down	0.000120919	-1.746203545	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04150|0|mcf:102132055|HRH2; histamine receptor H2; K04150 histamine receptor H2 (A)	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Gastric acid secretion (ko04971)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Histamine H2 receptor GN=HRH2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: histamine H2 receptor isoform X1 [Felis catus]
ENSG00000113758(DBN1)	--	60.60807314	3548	47.73837782	2879	57.82944124	3494	52.60382401	3088	61.36011976	3677	34.63701467	2085	0.973408926	-0.231058157	normal	0.92233669	0.331380469	normal	0.001089142	-0.752697133	normal	0.658860259	-0.186653545	normal	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	--	--	[Z]	Cytoskeleton	Cofilin/tropomyosin-type actin-binding protein	Drebrin GN=DBN1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: drebrin isoform X1 [Bos taurus]
ENSG00000113761(ZNF346)	--	5.426217188	460	6.339398438	546	6.061961854	429	6.3960705	585	8.276950023	749	5.947677193	544	0.876149968	0.315035595	normal	0.629205721	0.433608968	normal	0.855502508	0.333291891	normal	0.166833031	0.366593759	normal	--	--	--	--	--	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; U1 zinc finger;; C2H2 type zinc-finger (2 copies)	Zinc finger protein 346 GN=ZNF346 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 346 isoform X2 [Ailuropoda melanoleuca] 
ENSG00000113763(UNC5A)	--	0.09200342	7	0.012982077	1	0.062958114	4	0.132478	10	0.292435421	14	0.207083748	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K07521|0|hsa:90249|UNC5A, UNC5H1; unc-5 homolog A (C. elegans); K07521 netrin receptor unc-5 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	ZU5 domain;; Death domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	Netrin receptor UNC5A (Precursor) GN=UNC5A OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: netrin receptor UNC5A [Lipotes vexillifer]
ENSG00000113790(EHHADH)	--	3.030296591	195	2.599166237	157	3.345311312	185	3.601612891	240	3.296051661	211	3.071588035	204	0.926285228	0.266830294	normal	0.833138853	0.401703465	normal	0.960172093	0.131726654	normal	0.437183298	0.264993809	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: fatty acid metabolic process (GO:0006631);; Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07514|0|ptr:460996|EHHADH; enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase; K07514 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3,2-trans-enoyl-CoA isomerase [EC:4.2.1.17 1.1.1.35 5.3.3.8] (A)"	"Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146)"	[I]	Lipid transport and metabolism	"Enoyl-CoA hydratase/isomerase family;; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain"	3-hydroxyacyl-CoA dehydrogenase GN=EHHADH OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: peroxisomal bifunctional enzyme [Equus caballus]
ENSG00000113810(SMC4)	--	64.577588	3777	72.07785	4010	73.373687	4094	73.64207703	4257	77.00248695	4295	68.1719739	3656	0.98820555	0.141709724	normal	0.991136232	0.077601056	normal	0.985321394	-0.171469409	normal	0.95613985	0.017654356	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: chromosome (GO:0005694);; Biological Process: chromosome organization (GO:0051276);; 	"K06675|0|hsa:10051|SMC4, CAP-C, CAPC, SMC-4, SMC4L1, hCAP-C; structural maintenance of chromosomes 4; K06675 structural maintenance of chromosome 4 (A)"	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	RecF/RecN/SMC N terminal domain;; SMC proteins Flexible Hinge Domain;; AAA domain;; AAA domain	Structural maintenance of chromosomes protein 4 GN=SMC4 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: structural maintenance of chromosomes protein 4 isoform 1 [Tursiops truncatus] 
ENSG00000113811(SELENOK)	--	12.60411	211	12.65371	205	8.55106	149	14.96414	277	13.70858	245	15.12946	274	0.85458384	0.359520019	normal	0.936632732	0.234149549	normal	0.005892529	0.864008356	normal	0.078069506	0.472687387	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2763)	Selenoprotein K GN=SELK OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: selenoprotein K-like [Leptonychotes weddellii] 
ENSG00000113812(ACTR8)	--	5.9526474	502	7.62509661	545	6.48147	535	6.89684985	577	6.50641949	586	7.233483427	587	0.956813593	0.169567347	normal	0.969243322	0.082995755	normal	0.965389597	0.125192221	normal	0.640061201	0.124498459	normal	[Z]	Cytoskeleton	--	"K11673|0|hsa:93973|ACTR8, ARP8, INO80N, hArp8; ARP8 actin-related protein 8 homolog (yeast); K11673 actin-related protein 8 (A)"	--	[Z]	Cytoskeleton	Actin	Actin-related protein 8 GN=ACTR8 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: actin-related protein 8 isoform X1 [Galeopterus variegatus]
ENSG00000113838(TBCCD1)	--	3.570613	143	3.72167433	147	4.33756861	161	3.652084	159	4.105606942	148	3.784676615	150	0.963031279	0.120946657	normal	0.966617803	-0.011527351	normal	0.963662243	-0.109325488	normal	1	-0.002134715	normal	--	--	--	K16810|0|hsa:55171|TBCCD1; TBCC domain containing 1; K16810 TBCC domain-containing protein 1 (A)	--	[S]	Function unknown	Tubulin binding cofactor C	TBCC domain-containing protein 1 GN=TBCCD1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: TBCC domain-containing protein 1 [Ailuropoda melanoleuca] 
ENSG00000113845(TIMMDC1)	--	36.56469314	1260	38.639653	1213	40.61045071	1192	42.14082376	1351	35.62367682	1197	37.41538569	1271	0.980894389	0.069689605	normal	0.980689954	-0.040532086	normal	0.979432902	0.084184905	normal	0.892992905	0.037903431	normal	--	--	--	--	--	[S]	Function unknown	Tim17/Tim22/Tim23/Pmp24 family	"Complex I assembly factor TIMMDC1, mitochondrial GN=TIMMDC1 OS=Homo sapiens (Human) PE=1 SV=2"	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: complex I assembly factor TIMMDC1, mitochondrial [Oryctolagus cuniculus]"
ENSG00000113851(CRBN)	--	10.06280692	315	9.981368393	302	8.995214587	271	10.7270827	365	11.316914	395	14.79653975	490	0.950791941	0.1808922	normal	0.825267748	0.364278328	normal	0.001182865	0.842650519	normal	0.03127905	0.472772025	normal	[R]	General function prediction only	--	K11793|0|ptr:460130|CRBN; cereblon; K11793 cereblon (A)	--	[R]	General function prediction only	Putative binding domain;; ATP-dependent protease La (LON) domain	Protein cereblon GN=CRBN OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein cereblon isoform 1 [Dasypus novemcinctus]
ENSG00000113905(HRG)	--	0	0	0	0	0.0247237	0	0.0248317	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	--	--	--	--	Cystatin domain	Histidine-rich glycoprotein (Precursor) GN=HRG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: histidine-rich glycoprotein [Dasypus novemcinctus]
ENSG00000113916(BCL6)	--	2.089718641	156	2.77769565	207	2.663023035	197	1.717347695	127	2.336151587	177	6.596568407	298	0.917528655	-0.324005721	normal	0.935678001	-0.24536712	normal	0.295465899	0.585147951	normal	0.932488446	0.085756909	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15618|0|hsa:604|BCL6, BCL5, BCL6A, LAZ3, ZBTB27, ZNF51; B-cell CLL/lymphoma 6; K15618 B-cell lymphoma 6 protein (A)"	FoxO signaling pathway (ko04068);; Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding"	B-cell lymphoma 6 protein GN=BCL6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: B-cell lymphoma 6 protein isoform X1 [Tupaia chinensis] 
ENSG00000113924(HGD)	--	0.330704578	11	0.356641367	12	0.147698977	4	5.713235082	181	8.369811399	281	7.596552771	255	0	3.835168668	up	0	4.365799803	up	0	5.533103526	up	2.83E-23	4.709320222	up	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: homogentisate 1,2-dioxygenase activity (GO:0004411);; Biological Process: L-phenylalanine catabolic process (GO:0006559);; Biological Process: tyrosine metabolic process (GO:0006570);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00451|0|hsa:3081|HGD, AKU, HGO; homogentisate 1,2-dioxygenase (EC:1.13.11.5); K00451 homogentisate 1,2-dioxygenase [EC:1.13.11.5] (A)"	Tyrosine metabolism (ko00350)	[E]	Amino acid transport and metabolism	"homogentisate 1,2-dioxygenase"	"Homogentisate 1,2-dioxygenase GN=HGD OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: homogentisate 1,2-dioxygenase isoform X1 [Oryctolagus cuniculus]"
ENSG00000113946(CLDN16)	--	0.25862038	11	0	0	0.094747197	3	0.233170211	10	0.249698031	10	0.093074994	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06087|0|hsa:10686|CLDN16, HOMG3, PCLN1; claudin 16; K06087 claudin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-16 GN=CLDN16 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: claudin-16 [Felis catus]
ENSG00000113966(ARL6)	--	4.128819598	202	5.179012688	228	4.470724774	236	5.401954191	224	3.599507316	203	3.647100688	192	0.961356982	0.117462539	normal	0.949380029	-0.187660615	normal	0.907963442	-0.303809621	normal	0.752433264	-0.127108644	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07951|3.25686e-125|ptr:460539|ARL6; ADP-ribosylation factor-like 6; K07951 ADP-ribosylation factor-like protein 6 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Signal recognition particle receptor beta subunit;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region;; Miro-like protein	ADP-ribosylation factor-like protein 6 GN=ARL6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 6-like [Sus scrofa] 
ENSG00000113971(NPHP3)	--	8.911958172	796	8.890740743	668	7.4669698	697	5.969224	523	6.56529581	602	6.843847112	572	0.040917951	-0.635264809	normal	0.958093913	-0.171102903	normal	0.899719311	-0.292732632	normal	0.04621004	-0.369634136	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	"Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; NACHT domain"	Nephrocystin-3 GN=NPHP3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	nephrocystin-3 [Bos taurus] 
ENSG00000114019(AMOTL2)	--	21.58433021	1815	28.33212098	2562	32.16068181	2879	31.977945	2670	23.36835507	1969	28.89865498	2624	0.248965823	0.52566902	normal	0.779342263	-0.400963083	normal	0.984380154	-0.142013342	normal	0.975714352	-0.019544737	normal	--	--	--	--	--	--	--	Angiomotin C terminal	Angiomotin-like protein 2 GN=AMOTL2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: angiomotin-like protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000114021(NIT2)	--	19.505763	1069	20.180617	1059	18.659914	1053	19.187819	1043	16.09159	935	15.838442	962	0.978538143	-0.066258542	normal	0.957921397	-0.200785489	normal	0.971373571	-0.138479925	normal	0.538939582	-0.135152229	normal	[R]	General function prediction only	"Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; "	"K13566|0|hsa:56954|NIT2, HEL-S-8a; nitrilase family, member 2 (EC:3.5.1.3); K13566 omega-amidase [EC:3.5.1.3] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250)"	[E]	Amino acid transport and metabolism	Carbon-nitrogen hydrolase	Omega-amidase NIT2 GN=NIT2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: omega-amidase NIT2 isoform X1 [Galeopterus variegatus]
ENSG00000114023(FAM162A)	--	29.90721049	696	22.90013001	546	25.13765026	627	35.1922103	771	22.91475025	522	21.82495023	516	0.969689146	0.116566743	normal	0.968352043	-0.086033963	normal	0.902255204	-0.288617184	normal	0.888514103	-0.069584052	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1075)	Protein FAM162A GN=FAM162A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM162A [Orycteropus afer afer]
ENSG00000114026(OGG1)	--	9.738005579	339	9.995752797	346	10.84733721	381	7.874578561	267	6.9742378	237	7.566738017	262	0.819107015	-0.373365775	normal	0.314155816	-0.564312405	normal	0.334205119	-0.545887114	normal	0.031236261	-0.497899371	normal	[L]	"Replication, recombination and repair"	Molecular Function: damaged DNA binding (GO:0003684);; Biological Process: base-excision repair (GO:0006284);; Biological Process: nucleotide-excision repair (GO:0006289);; Molecular Function: oxidized purine nucleobase lesion DNA N-glycosylase activity (GO:0008534);; 	K03660|0|ggo:101145280|OGG1; N-glycosylase/DNA lyase isoform 1; K03660 N-glycosylase/DNA lyase [EC:3.2.2.- 4.2.99.18] (A)	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	"8-oxoguanine DNA glycosylase, N-terminal domain;; HhH-GPD superfamily base excision DNA repair protein"	DNA-(apurinic or apyrimidinic site) lyase GN=OGG1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: N-glycosylase/DNA lyase [Galeopterus variegatus]
ENSG00000114030(KPNA1)	--	20.50022438	1734	20.9404492	1775	23.53163395	1838	23.232561	2122	27.00170115	2080	23.08333466	1907	0.950354263	0.260279741	normal	0.969008619	0.207174753	normal	0.985727011	0.044840413	normal	0.370617833	0.170794378	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein import into nucleus (GO:0006606);; Molecular Function: protein transporter activity (GO:0008565);; 	"K15042|0|hsa:3836|KPNA1, IPOA5, NPI-1, RCH2, SRP1; karyopherin alpha 1 (importin alpha 5); K15042 importin subunit alpha-1 (A)"	Influenza A (ko05164)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Armadillo/beta-catenin-like repeat;; Importin beta binding domain;; HEAT repeats;; HEAT-like repeat;; HEAT repeat;; Armadillo-like	"Importin subunit alpha-5, N-terminally processed GN=KPNA1 OS=Homo sapiens (Human) PE=1 SV=3"	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin subunit alpha-5 isoform X1 [Panthera tigris altaica]
ENSG00000114054(PCCB)	--	19.76231967	649	19.52281022	645	18.70295368	612	24.26895254	783	19.73365145	637	23.51585534	745	0.936893817	0.239444908	normal	0.973146943	-0.039339531	normal	0.915104449	0.274800943	normal	0.485495997	0.162288575	normal	[I]	Lipid transport and metabolism	--	"K01966|0|hsa:5096|PCCB; propionyl CoA carboxylase, beta polypeptide (EC:6.4.1.3); K01966 propionyl-CoA carboxylase beta chain [EC:6.4.1.3] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640)"	[EI]	Amino acid transport and metabolism;; Lipid transport and metabolism	Carboxyl transferase domain	"Propionyl-CoA carboxylase beta chain, mitochondrial (Precursor) GN=PCCB OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: propionyl-CoA carboxylase beta chain, mitochondrial [Ceratotherium simum simum]"
ENSG00000114062(UBE3A)	--	25.76214031	1521	29.93244699	1596	26.74865696	1609	28.06903208	1450	33.8166465	1599	27.42710733	1441	0.980613382	-0.099696354	normal	0.984216573	-0.018699569	normal	0.973234512	-0.167219263	normal	0.676851969	-0.095008706	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	"K10587|0|hsa:7337|UBE3A, ANCR, AS, E6-AP, EPVE6AP, HPVE6A; ubiquitin protein ligase E3A (EC:6.3.2.19); K10587 ubiquitin-protein ligase E3 A [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase)	Ubiquitin-protein ligase E3A GN=UBE3A OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-protein ligase E3A isoform X1 [Galeopterus variegatus]
ENSG00000114098(ARMC8)	--	10.39113908	476	9.58911763	481	11.78808499	477	11.86230915	585	12.00622364	527	10.47766189	494	0.918052398	0.265867611	normal	0.965333799	0.110009005	normal	0.970763311	0.042099174	normal	0.5922508	0.141703368	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT repeat;; HEAT-like repeat;; Armadillo-like	Armadillo repeat-containing protein 8 GN=ARMC8 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: armadillo repeat-containing protein 8 isoformX3 [Canis lupus familiaris] 
ENSG00000114107(CEP70)	--	6.434007682	238	7.831403978	259	7.219264011	241	5.514035289	215	6.421364055	228	6.454854976	223	0.952601254	-0.176259289	normal	0.944630029	-0.204073803	normal	0.961000265	-0.119501106	normal	0.633856798	-0.169225404	normal	--	--	--	K16802|0|ggo:101148864|CEP70; centrosomal protein of 70 kDa isoform 1; K16802 centrosomal protein CEP70 (A)	--	--	--	--	Centrosomal protein of 70 kDa GN=CEP70 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 70 kDa [Tupaia chinensis]
ENSG00000114115(RBP1)	--	2.271493881	30	2.357042099	23	3.113632	37	1.847936604	19	2.427819139	20	1.007742099	13	0.960797301	-0.647760848	normal	0.986005754	-0.2083567	normal	0.308720802	-1.415740498	normal	0.226878001	-0.812865588	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family	Retinol-binding protein 1 GN=RBP1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: retinol-binding protein 1 [Loxodonta africana]
ENSG00000114120(SLC25A36)	--	19.08053983	1248	22.506798	1335	17.96061494	1229	16.47488978	1102	16.169815	1034	20.40394108	1351	0.958380358	-0.210050544	normal	0.765217734	-0.389527218	normal	0.976209084	0.128100925	normal	0.46976644	-0.149276688	normal	--	--	--	"K15116|0|hsa:55186|SLC25A36, PNC2; solute carrier family 25 (pyrimidine nucleotide carrier), member 36; K15116 solute carrier family 25, member 33/36 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 36 GN=SLC25A36 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 36 isoform X1 [Lipotes vexillifer]
ENSG00000114125(RNF7)	--	48.0268659	1008	41.6942858	926	51.06499013	1024	53.43565028	1106	51.0921658	1009	51.5238517	1067	0.975987704	0.102873759	normal	0.974445749	0.102255507	normal	0.97916819	0.050979259	normal	0.73222535	0.084099408	normal	[OD]	"Posttranslational modification, protein turnover, chaperones;; Cell cycle control, cell division, chromosome partitioning"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: zinc ion binding (GO:0008270);; 	K10611|1.51268e-64|ptr:100612089|RNF7; ring finger protein 7; K10611 RING-box protein 2 (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	RING-H2 zinc finger;; Anaphase-promoting complex subunit 11 RING-H2 finger;; Ring finger domain	RING-box protein 2 GN=RNF7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING-box protein 2 isoform X1 [Erinaceus europaeus]
ENSG00000114126(TFDP2)	--	11.81599856	1041	8.963941876	996	13.89619489	964	8.744653316	1035	10.22917513	1073	9.736042299	945	0.979419865	-0.039113668	normal	0.976641811	0.085880224	normal	0.978565346	-0.036951709	normal	0.995489851	0.003281995	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09392|0|mcc:714655|TFDP2; transcription factor Dp-2 (E2F dimerization partner 2); K09392 transcription factor Dp-2 (A)	Cell cycle (ko04110)	[K]	Transcription	Transcription factor DP;; E2F/DP family winged-helix DNA-binding domain	Transcription factor Dp-2 GN=TFDP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor Dp-2 isoform X4 [Mustela putorius furo] 
ENSG00000114127(XRN1)	--	4.340747557	620	4.933798673	699	4.275106256	610	4.94420397	777	5.16653909	710	5.675221443	792	0.899300348	0.29416184	normal	0.974910934	0.001097655	normal	0.796182521	0.367597786	normal	0.294104988	0.219211189	normal	[LDA]	"Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning;; RNA processing and modification"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: exonuclease activity (GO:0004527);; 	K12618|0|pps:100975490|XRN1; 5'-3' exoribonuclease 1; K12618 5'-3' exoribonuclease 1 [EC:3.1.13.-] (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA degradation (ko03018)	[LD]	"Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	XRN 5'-3' exonuclease N-terminus	5'-3' exoribonuclease 1 GN=XRN1 OS=Homo sapiens (Human) PE=1 SV=1	DL	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	PREDICTED: 5'-3' exoribonuclease 1 isoform 1 [Orcinus orca]
ENSG00000114166(KAT2B)	--	6.671873	572	7.54085322	647	6.668696	566	5.995264	515	5.244039	449	7.704148	662	0.953949176	-0.181760122	normal	0.235466902	-0.546933066	normal	0.944462224	0.217200607	normal	0.618343093	-0.155238225	normal	[BK]	Chromatin structure and dynamics;; Transcription	"Molecular Function: histone acetyltransferase activity (GO:0004402);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: N-acetyltransferase activity (GO:0008080);; "	K06062|0|ggo:101145647|KAT2B; histone acetyltransferase KAT2B; K06062 histone acetyltransferase [EC:2.3.1.48] (A)	Notch signaling pathway (ko04330);; Thyroid hormone signaling pathway (ko04919);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[BK]	Chromatin structure and dynamics;; Transcription	PCAF (P300/CBP-associated factor) N-terminal domain;; Bromodomain;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) family	Histone acetyltransferase KAT2B GN=KAT2B OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase KAT2B [Odobenus rosmarus divergens]
ENSG00000114200(BCHE)	--	5.457963775	227	4.152947234	171	4.090067944	166	6.022138937	232	5.719947228	213	4.792092895	150	0.96700891	0.000596252	normal	0.916512203	0.293104044	normal	0.95920987	-0.15304476	normal	0.918963057	0.054549752	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01050|0|hsa:590|BCHE, CHE1, CHE2, E1; butyrylcholinesterase (EC:3.1.1.8); K01050 cholinesterase [EC:3.1.1.8] (A)"	--	[T]	Signal transduction mechanisms	Carboxylesterase family;; Acetylcholinesterase tetramerisation domain;; alpha/beta hydrolase fold	Cholinesterase (Precursor) GN=BCHE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cholinesterase isoform X1 [Loxodonta africana]
ENSG00000114204(SERPINI2)	--	0	0	0	0	0	0	0	0	0	0	0.020929131	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin I2 (Precursor) GN=SERPINI2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: serpin I2 [Balaenoptera acutorostrata scammoni]
ENSG00000114209(PDCD10)	--	29.1478942	620	30.2694146	638	32.415695	682	26.2628295	574	24.9610399	541	27.43541133	564	0.96349921	-0.141684696	normal	0.9238564	-0.258687625	normal	0.908722296	-0.281680085	normal	0.288670528	-0.229577649	normal	--	--	--	K18269|1.15111e-152|tup:102493524|PDCD10; programmed cell death 10; K18269 programmed cell death protein 10 (A)	--	[S]	Function unknown	Protein of unknown function (DUF1241)	Programmed cell death protein 10 GN=PDCD10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: programmed cell death protein 10 [Myotis brandtii] 
ENSG00000114248(LRRC31)	--	0	0	0	0	0	0	0.035973562	1	0.173926846	6	0.075843487	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine rich repeat;; Leucine Rich Repeat	Leucine-rich repeat-containing protein 31 GN=LRRC31 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 31 [Galeopterus variegatus]
ENSG00000114251(WNT5A)	--	1.025608826	38	0.37532886	35	0.919571904	31	1.3069487	89	2.160136098	136	0.66594453	59	0.026898267	1.165343324	normal	2.30E-08	1.892241543	up	0.622262899	0.888248045	normal	0.031712987	1.427214606	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00444|0|cjc:100401066|WNT5A; wingless-type MMTV integration site family, member 5A; K00444 wingless-type MMTV integration site family, member 5 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-5a (Precursor) GN=WNT5A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-5a isoform X1 [Galeopterus variegatus]
ENSG00000114268(PFKFB4)	--	4.0161258	275	5.071737548	354	4.65828543	332	5.615529044	366	4.315751354	278	5.158046137	339	0.805157019	0.379735476	normal	0.825009334	-0.368310739	normal	0.968309548	0.021712712	normal	0.985148518	0.01115144	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: 6-phosphofructo-2-kinase activity (GO:0003873);; Molecular Function: ATP binding (GO:0005524);; Biological Process: fructose metabolic process (GO:0006000);; 	"K01103|0|pps:100978268|PFKFB4; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4; K19030 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 4 [EC:2.7.1.105 3.1.3.46] (A)"	Fructose and mannose metabolism (ko00051);; HIF-1 signaling pathway (ko04066);; AMPK signaling pathway (ko04152)	[G]	Carbohydrate transport and metabolism	6-phosphofructo-2-kinase;; Histidine phosphatase superfamily (branch 1);; AAA domain	"Fructose-2,6-bisphosphatase GN=PFKFB4 OS=Homo sapiens (Human) PE=2 SV=6"	G	Carbohydrate transport and metabolism	"PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoformX1 [Sus scrofa]"
ENSG00000114270(COL7A1)	--	18.618981	4425	17.223881	4288	16.525802	4097	26.187972	6233	28.95303455	6792	28.823752	6868	0.643802669	0.463280879	normal	0.037926608	0.641923629	normal	0.00210628	0.736818353	normal	2.88E-05	0.614014491	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Molecular Function: protein binding (GO:0005515);; 	"K16628|0|hsa:1294|COL7A1, EBD1, EBDCT, EBR1, NDNC8; collagen, type VII, alpha 1; K16628 collagen, type VII, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	"Collagen triple helix repeat (20 copies);; Fibronectin type III domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; Kunitz/Bovine pancreatic trypsin inhibitor domain;; Interferon-alpha/beta receptor, fibronectin type III"	Collagen alpha-1(VII) chain (Precursor) GN=COL7A1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(VII) chain [Galeopterus variegatus]
ENSG00000114279(FGF12)	--	2.51243475	136	2.742170533	163	4.877345197	138	6.383680763	412	7.015365473	418	6.864584269	408	8.92E-12	1.55759751	up	1.14E-08	1.329228255	up	1.29E-11	1.545283348	up	4.72E-13	1.480921415	up	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|4.60994e-180|pps:100980469|FGF12; fibroblast growth factor 12; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 12 GN=FGF12 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: fibroblast growth factor 12 isoform 1 [Trichechus manatus latirostris] 
ENSG00000114302(PRKAR2A)	--	17.06363244	1258	15.93013621	1198	14.8586523	1266	19.6846313	1720	18.95302534	1602	18.20962554	1444	0.672668045	0.420004145	normal	0.753709984	0.397384524	normal	0.968608983	0.181298981	normal	0.037187182	0.335056624	normal	--	--	--	"K04739|0|hsa:5576|PRKAR2A, PKR2, PRKAR2; protein kinase, cAMP-dependent, regulatory, type II, alpha (EC:2.7.11.1); K04739 cAMP-dependent protein kinase regulator (A)"	Apoptosis (ko04210);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	Cyclic nucleotide-binding domain;; Regulatory subunit of type II PKA R-subunit	cAMP-dependent protein kinase type II-alpha regulatory subunit GN=PRKAR2A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inositol hexakisphosphate kinase 2 isoform X5 [Galeopterus variegatus]
ENSG00000114315(HES1)	--	2.23711	55	0.771697	19	0.79072	19	1.46022	36	3.0209	75	1.39725	35	0.899199214	-0.620671089	normal	5.91E-05	1.878778155	up	0.907074254	0.824079571	normal	0.587763889	0.629027137	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K06054|1.0645e-155|ptr:460942|HES1; hes family bHLH transcription factor 1; K06054 hairy and enhancer of split 1 (A)	Fanconi anemia pathway (ko03460);; Notch signaling pathway (ko04330);; Maturity onset diabetes of the young (ko04950)	[K]	Transcription	Hairy Orange;; Helix-loop-helix DNA-binding domain	Transcription factor HES-1 GN=HES1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor HES-1 [Pteropus alecto]
ENSG00000114316(USP4)	--	7.119667074	561	7.338457446	576	8.234551538	588	6.501617856	554	6.645415405	543	8.017305818	627	0.97181093	-0.048812528	normal	0.966950816	-0.106255787	normal	0.970707294	0.084148233	normal	0.955958996	-0.021618975	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11835|0|pps:100967331|USP4; ubiquitin specific peptidase 4 (proto-oncogene); K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin-like domain;; Ubiquitin carboxyl-terminal hydrolase;; DUSP domain	Ubiquitin carboxyl-terminal hydrolase 4 GN=USP4 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 4 isoform X1 [Felis catus]
ENSG00000114331(ACAP2)	--	6.607839141	754	7.049179278	784	6.469080123	719	16.51425528	842	6.574227092	747	6.317060968	719	0.969349411	0.128176211	normal	0.972339873	-0.090992131	normal	0.975769239	-0.008274039	normal	0.978728302	0.01041466	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; 	"K12489|0|pps:100969566|ACAP2; ArfGAP with coiled-coil, ankyrin repeat and PH domains 2; K12489 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; PH domain;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 GN=ACAP2 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 [Ceratotherium simum simum]"
ENSG00000114346(ECT2)	--	62.84490925	4201	62.42280811	4181	72.0709605	4670	55.28299869	3641	47.203478	3133	58.34967841	3846	0.974977215	-0.237137047	normal	0.715422114	-0.437546309	normal	0.959481646	-0.288252199	normal	0.050693606	-0.318382575	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; twin BRCT domain;; BRCA1 C Terminus (BRCT) domain	Protein ECT2 GN=ECT2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: protein ECT2 isoform X1 [Galeopterus variegatus]
ENSG00000114353(GNAI2)	--	30.289768	1430	29.11289893	1337	28.70972162	1378	29.6884436	1403	28.94008863	1375	25.841761	1214	0.982346888	-0.058269193	normal	0.982453259	0.018984421	normal	0.965671973	-0.190875569	normal	0.755919668	-0.075847121	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04630|0|mcc:703780|GNAI2; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2; K04630 guanine nucleotide-binding protein G(i) subunit alpha (A)"	Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Axon guidance (ko04360);; Tight junction (ko04530);; Gap junction (ko04540);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pertussis (ko05133);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Guanine nucleotide-binding protein G(i) subunit alpha-2 GN=GNAI2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(i) subunit alpha-2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000114354(TFG)	--	80.74221035	2637	83.86012203	2706	78.26385663	2547	86.47503987	2797	91.89307653	2981	79.04857097	2575	0.98884416	0.054119801	normal	0.98625415	0.118145054	normal	0.989000176	0.007477615	normal	0.807348629	0.060803444	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K09292|0|ptr:460557|TFG; TRK-fused gene; K09292 protein TFG (A)	Pathways in cancer (ko05200);; Thyroid cancer (ko05216)	--	--	PB1 domain	Protein TFG GN=TFG OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein TFG isoform 1 [Dasypus novemcinctus]
ENSG00000114374(USP9Y)	--	31.92670522	1499	34.41427	1532	30.0353536	1482	14.80139208	591	11.69196826	597	14.2740584	644	1.96E-13	-1.371279017	down	3.27E-13	-1.378775875	down	2.46E-10	-1.208777915	down	1.30E-21	-1.321647839	down	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11840|0|hsa:8287|USP9Y, DFFRY, SPGFY2; ubiquitin specific peptidase 9, Y-linked (EC:3.4.19.12); K11840 ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Probable ubiquitin carboxyl-terminal hydrolase FAF-Y GN=USP9Y OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X2 [Felis catus]
ENSG00000114378(HYAL1)	--	1.670245756	65	1.512429771	54	1.592817371	48	0.592321622	21	0.55515994	23	0.516053999	23	0.003084998	-1.591308983	down	0.202816919	-1.199775816	normal	0.585824512	-1.022190512	normal	0.006557875	-1.338831985	down	--	--	Molecular Function: hyalurononglucosaminidase activity (GO:0004415);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K01197|0|hsa:3373|HYAL1, HYAL-1, LUCA1, NAT6; hyaluronoglucosaminidase 1 (EC:3.2.1.35); K01197 hyaluronoglucosaminidase [EC:3.2.1.35] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	--	--	Hyaluronidase	Hyaluronidase-1 (Precursor) GN=HYAL1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: hyaluronidase-2 isoform X2 [Equus caballus] 
ENSG00000114388(NPRL2)	--	6.7444	202	5.46359	164	6.19914	188	7.45693	225	7.42892	223	7.87768	238	0.960669022	0.123844662	normal	0.804175558	0.418599565	normal	0.890992766	0.329576094	normal	0.379188564	0.287384881	normal	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Nitrogen permease regulator 2	Nitrogen permease regulator 2-like protein GN=NPRL2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	hypothetical protein CB1_000145020 [Camelus ferus]
ENSG00000114391(RPL24)	--	939.03712	5935	890.56275	5734	909.80615	6011	1070.13941	7279	1071.96579	6829	916.20644	6096	0.977697223	0.263598269	normal	0.983390577	0.230650072	normal	0.994325136	0.011963452	normal	0.399727485	0.170872493	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02896|2.63469e-76|shr:100915234|RPL24; ribosomal protein L24; K02896 large subunit ribosomal protein L24e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L24e	60S ribosomal protein L24 GN=RPL24 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L24-like [Bubalus bubalis]
ENSG00000114395(CYB561D2)	--	13.65256	224	15.310038	253	14.24853016	250	13.88856	240	13.98711	232	15.027753	250	0.965148902	0.068251114	normal	0.95638757	-0.145530362	normal	0.967173591	-0.008241588	normal	0.954602665	-0.030981212	normal	--	--	--	K08371|1.38186e-120|nle:100594652|cytochrome b561 domain-containing protein 2-like; K08371 cytochrome b-561 domain containing protein 2 (A)	--	--	--	Eukaryotic cytochrome b561	Cytochrome b561 domain-containing protein 2 GN=CYB561D2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: cytochrome b561 domain-containing protein 2 [Galeopterus variegatus]
ENSG00000114405(C3orf14)	--	20.44871688	175	25.01979206	211	26.22225897	223	15.01127829	141	15.911056	136	21.86285144	188	0.902685884	-0.339167061	normal	0.264890276	-0.64921822	normal	0.933217853	-0.252733447	normal	0.195175416	-0.409334049	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4570)	Uncharacterized protein C3orf14 GN=C3orf14 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C3orf14 homolog [Galeopterus variegatus] 
ENSG00000114416(FXR1)	--	43.83026872	2066	47.6883509	2257	49.70746495	2364	47.35899415	2278	39.4894134	1884	38.98181218	1814	0.984271709	0.110017295	normal	0.941832207	-0.281827002	normal	0.790448627	-0.390061299	normal	0.327396894	-0.183971334	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K15516|0|pps:100973513|FXR1; fragile X mental retardation, autosomal homolog 1; K15516 fragile X mental retardation protein (A)"	RNA transport (ko03013)	--	--	Fragile X-related 1 protein C terminal;; KH domain;; Agenet domain;; KH domain	Fragile X mental retardation syndrome-related protein 1 GN=FXR1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: fragile X mental retardation syndrome-related protein 1 isoform X4 [Balaenoptera acutorostrata scammoni]
ENSG00000114423(CBLB)	--	5.78951436	446	7.0929658	681	8.081991113	422	4.451807	369	5.501715112	461	7.150122497	702	0.889897586	-0.303105117	normal	0.136370086	-0.582731114	normal	0.007587811	0.723904066	normal	0.971576238	-0.035772672	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: nucleus (GO:0005634);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Molecular Function: metal ion binding (GO:0046872);; 	"K04707|0|hsa:868|CBLB, Cbl-b, RNF56; Cbl proto-oncogene B, E3 ubiquitin protein ligase; K04707 E3 ubiquitin-protein ligase CBL [EC:6.3.2.19] (A)"	ErbB signaling pathway (ko04012);; Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; Jak-STAT signaling pathway (ko04630);; T cell receptor signaling pathway (ko04660);; Insulin signaling pathway (ko04910);; Bacterial invasion of epithelial cells (ko05100);; Measles (ko05162);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Chronic myeloid leukemia (ko05220)	[V]	Defense mechanisms	"CBL proto-oncogene N-terminal domain 1;; CBL proto-oncogene N-terminus, SH2-like domain;; CBL proto-oncogene N-terminus, EF hand-like domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; UBA/TS-N domain"	E3 ubiquitin-protein ligase CBL-B GN=CBLB OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: E3 ubiquitin-protein ligase CBL-B isoform X1 [Mustela putorius furo] 
ENSG00000114439(BBX)	--	25.78435158	3611	26.18163289	3600	26.25266878	3699	30.64733968	3931	24.11241599	3197	21.81946404	2980	0.990260186	0.091628309	normal	0.981010247	-0.192618795	normal	0.930864204	-0.319968369	normal	0.530923851	-0.132192347	normal	--	--	--	--	--	[K]	Transcription	Domain of unknown function (DUF2028);; HMG (high mobility group) box;; HMG-box domain	HMG box transcription factor BBX GN=BBX OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: HMG box transcription factor BBX isoform 1 [Ceratotherium simum simum]
ENSG00000114446(IFT57)	--	10.84793238	628	9.628745377	559	10.99765512	630	14.23290374	831	13.02448007	751	10.50152617	608	0.785173262	0.372457319	normal	0.718776991	0.403593014	normal	0.972564996	-0.059426728	normal	0.234447611	0.247407435	normal	--	--	--	"K04638|0|hsa:55081|IFT57, ESRRBL1, HIPPI, MHS4R2; intraflagellar transport 57; K04638 estrogen-related receptor beta like 1 (A)"	Huntington's disease (ko05016)	[T]	Signal transduction mechanisms	Intra-flagellar transport protein 57	Intraflagellar transport protein 57 homolog GN=IFT57 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: intraflagellar transport protein 57 homolog [Panthera tigris altaica]
ENSG00000114450(GNB4)	--	8.141221616	769	9.004732821	831	8.646745182	794	9.43032012	900	7.907017233	740	7.644241594	658	0.956267542	0.195747358	normal	0.95711059	-0.188386214	normal	0.913267643	-0.27875873	normal	0.763057888	-0.081249689	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K04538|0|ptr:460862|GNB4; guanine nucleotide binding protein (G protein), beta polypeptide 4; K04538 guanine nucleotide-binding protein subunit beta-4 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[R]	General function prediction only	"WD domain, G-beta repeat"	Guanine nucleotide-binding protein subunit beta-4 GN=GNB4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit beta-4 isoform X1 [Oryctolagus cuniculus]
ENSG00000114455(HHLA2)	--	0	0	0	0	0	0	0.322383684	13	1.354759057	16	0.990429499	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin C1-set domain	HERV-H LTR-associating protein 2 (Precursor) GN=HHLA2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: HERV-H LTR-associating protein 2 [Galeopterus variegatus]
ENSG00000114473(IQCG)	--	2.635141	125	2.707373	128	2.850305	140	1.859520117	91	3.042078	131	2.730016209	130	0.830691133	-0.481848372	normal	0.967382546	0.011857962	normal	0.964488744	-0.113929193	normal	0.713453307	-0.178856672	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	IQ calmodulin-binding motif	IQ domain-containing protein G GN=IQCG OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: IQ domain-containing protein G [Galeopterus variegatus]
ENSG00000114480(GBE1)	--	28.71751	1486	33.24523	1777	30.52113	1635	33.88183	1812	21.80449	1157	26.89392	1416	0.948572422	0.255077437	normal	0.02872236	-0.639801059	normal	0.962159592	-0.215546382	normal	0.581237946	-0.181817831	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: cation binding (GO:0043169);; "	"K00700|0|hsa:2632|GBE1, APBD, GBE, GSD4; glucan (1,4-alpha-), branching enzyme 1 (EC:2.4.1.18); K00700 1,4-alpha-glucan branching enzyme [EC:2.4.1.18] (A)"	Starch and sucrose metabolism (ko00500)	[G]	Carbohydrate transport and metabolism	"Alpha amylase, C-terminal all-beta domain;; Alpha amylase, catalytic domain;; Carbohydrate-binding module 48 (Isoamylase N-terminal domain)"	"1,4-alpha-glucan-branching enzyme GN=GBE1 OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: 1,4-alpha-glucan-branching enzyme [Galeopterus variegatus]"
ENSG00000114491(UMPS)	--	9.698848	1141	9.906833	1183	16.301335	1231	49.51239085	1130	17.749002	1150	9.060071323	1064	0.980297696	-0.044747733	normal	0.979513917	-0.062162169	normal	0.955296605	-0.21833527	normal	0.629022553	-0.109519775	normal	[F]	Nucleotide transport and metabolism	Molecular Function: orotidine-5'-phosphate decarboxylase activity (GO:0004590);; Biological Process: 'de novo' pyrimidine nucleobase biosynthetic process (GO:0006207);; Biological Process: nucleoside metabolic process (GO:0009116);; 	"K13421|0|hsa:7372|UMPS, OPRT; uridine monophosphate synthetase (EC:2.4.2.10 4.1.1.23); K13421 uridine monophosphate synthetase [EC:2.4.2.10 4.1.1.23] (A)"	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Orotidine 5'-phosphate decarboxylase / HUMPS family;; Phosphoribosyl transferase domain	Orotidine 5'-phosphate decarboxylase GN=UMPS OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: uridine 5'-monophosphate synthase [Oryctolagus cuniculus]
ENSG00000114503(NCBP2)	--	35.16625982	1110	35.11986705	1134	32.00332333	1043	39.56107129	1297	37.23155218	1238	36.26258591	1114	0.963505013	0.193538533	normal	0.976926716	0.105030036	normal	0.977627492	0.086597121	normal	0.550224736	0.128965018	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12883|3.22444e-97|mcf:102119030|NCBP2; nuclear cap binding protein subunit 2, 20kDa; K12883 nuclear cap-binding protein subunit 2 (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Nuclear cap-binding protein subunit 2 GN=NCBP2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: nuclear cap-binding protein subunit 2 isoform X2 [Camelus dromedarius] 
ENSG00000114520(SNX4)	--	10.152215	433	11.15888	477	12.09296	510	10.23962	444	11.194609	475	8.697583	371	0.970469511	0.005341671	normal	0.970214049	-0.027401256	normal	0.544647202	-0.465743236	normal	0.553535676	-0.159956652	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17919|0|ptr:460652|SNX4; sorting nexin 4; K17919 sorting nexin-4 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain;; Vps5 C terminal like	Sorting nexin-4 GN=SNX4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: sorting nexin-4 [Oryctolagus cuniculus]
ENSG00000114529(C3orf52)	--	5.621963896	301	5.40950812	295	6.547011	318	11.18602475	514	11.152496	531	9.250569417	431	0.010273327	0.738257376	normal	0.001795351	0.823381425	normal	0.684657319	0.42861238	normal	0.000557978	0.669907341	normal	--	--	--	--	--	--	--	--	TPA-induced transmembrane protein GN=TTMP OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: TPA-induced transmembrane protein [Ceratotherium simum simum]
ENSG00000114541(FRMD4B)	--	0.362209084	33	0.200597885	17	0.579422279	24	0.345235105	30	0.52845256	44	0.644265746	56	0.983246797	-0.160494833	normal	0.306130679	1.277577606	normal	0.230374738	1.164741257	normal	0.177876542	0.793637093	normal	--	--	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF3338);; FERM central domain;; FERM C-terminal PH-like domain;; FERM N-terminal domain	FERM domain-containing protein 4B GN=FRMD4B OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: FERM domain-containing protein 4B isoform X6 [Canis lupus familiaris]
ENSG00000114544(SLC41A3)	--	14.49191693	448	12.28134605	409	11.50762546	376	18.64840905	650	20.2744921	676	19.756813	658	0.365317998	0.504664543	normal	0.015609351	0.701458524	normal	0.001595235	0.796610606	normal	0.000139142	0.664899506	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; 	"K15122|0|hsa:54946|SLC41A3, SLC41A1-L2; solute carrier family 41, member 3; K15122 solute carrier family 41 (A)"	--	[P]	Inorganic ion transport and metabolism	Divalent cation transporter	Solute carrier family 41 member 3 GN=SLC41A3 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 41 member 3 isoform X1 [Galeopterus variegatus] 
ENSG00000114554(PLXNA1)	--	9.9624087	1919	11.229043	2174	10.35668153	2020	12.45304549	2368	11.5107609	2184	12.28724	2352	0.947275212	0.27228557	normal	0.987264875	-0.014795374	normal	0.97049292	0.211094735	normal	0.432098747	0.154258482	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06820|0|hsa:5361|PLXNA1, NOV, NOVP, PLEXIN-A1, PLXN1; plexin A1; K06820 plexin A (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; Sema domain;; IPT/TIG domain;; Plexin repeat	Plexin-A1 (Precursor) GN=PLXNA1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: plexin-A1 [Ochotona princeps]
ENSG00000114573(ATP6V1A)	--	21.58276546	1496	21.37790913	1483	23.64019	1518	26.31075911	1800	22.81566575	1575	27.61796592	1841	0.956832846	0.235833419	normal	0.982529236	0.065342012	normal	0.941464804	0.269781986	normal	0.300277365	0.192834041	normal	[C]	Energy production and conversion	Molecular Function: ATP binding (GO:0005524);; Biological Process: proton transport (GO:0015992);; Biological Process: ATP metabolic process (GO:0046034);; 	"K02145|0|pps:100980582|ATP6V1A; ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A; K02145 V-type H+-transporting ATPase subunit A [EC:3.6.3.14] (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	"ATP synthase alpha/beta family, nucleotide-binding domain;; ATP synthase alpha/beta chain, C terminal domain;; ATP synthase alpha/beta family, beta-barrel domain"	V-type proton ATPase catalytic subunit A GN=ATP6V1A OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: V-type proton ATPase catalytic subunit A isoform X1 [Tupaia chinensis]
ENSG00000114626(ABTB1)	--	6.19581945	206	5.430253969	185	5.96186804	205	5.674024867	191	6.246635219	205	6.490580552	215	0.959212862	-0.138828248	normal	0.959536666	0.125695703	normal	0.965614802	0.059989152	normal	0.985016047	0.015148151	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10520|0|pps:100967307|ABTB1; ankyrin repeat and BTB (POZ) domain containing 1; K10520 ankyrin repeat and BTB/POZ domain-containing protein 1 (A)	--	--	--	BTB/POZ domain;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Ankyrin repeat and BTB/POZ domain-containing protein 1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and BTB/POZ domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000114631(PODXL2)	--	5.47476	269	5.3857	272	6.16467	313	10.1578	502	11.7964	575	9.12305	451	0.000662913	0.865575485	normal	3.98E-06	1.054406482	up	0.390916664	0.516582931	normal	1.50E-05	0.818207279	normal	--	--	--	"K06818|0|hsa:50512|PODXL2, EG, PODLX2; podocalyxin-like 2; K06818 podocalyxin-like 2 (A)"	--	--	--	CD34/Podocalyxin family	Podocalyxin-like protein 2 (Precursor) GN=PODXL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: podocalyxin-like protein 2 [Equus caballus]
ENSG00000114638(UPK1B)	--	0.058759331	2	0.167028807	5	0	0	4.459608615	114	2.768850684	93	2.59210049	72	0	5.005976434	up	2.55E-15	3.840499862	up	3.33E-16	5.599125567	up	1.21E-21	5.291249996	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17347|0|hsa:7348|UPK1B, TSPAN20, UPIB, UPK1; uroplakin 1B; K17347 uroplakin 1 (A)"	--	[R]	General function prediction only	Tetraspanin family	Uroplakin-1b GN=UPK1B OS=Homo sapiens (Human) PE=2 SV=5	R	General function prediction only	PREDICTED: uroplakin-1b [Equus caballus] 
ENSG00000114646(CSPG5)	--	3.8331792	175	2.52595492	117	3.9902808	180	2.4808907	111	2.0315927	89	1.24938084	56	0.272365874	-0.680061227	normal	0.893951472	-0.409961935	normal	1.91E-08	-1.666272964	down	0.019902892	-0.905302038	normal	--	--	--	K08116|0|ecb:100064520|CSPG5; chondroitin sulfate proteoglycan 5 (neuroglycan C); K08116 chondroitin sulfate proteoglycan 5 (A)	--	--	--	Chondroitin sulphate attachment domain;; Neural chondroitin sulphate proteoglycan cytoplasmic domain	Chondroitin sulfate proteoglycan 5 (Precursor) GN=CSPG5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: chondroitin sulfate proteoglycan 5 isoform X1 [Equus caballus]
ENSG00000114648(KLHL18)	--	5.53811489	424	6.140348	420	4.858538	448	6.239182112	556	5.444722428	536	4.501371	436	0.816431285	0.35904927	normal	0.862046182	0.329365065	normal	0.969663947	-0.047300182	normal	0.359562871	0.220282937	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10455|0|hsa:23276|KLHL18; kelch-like family member 18; K10455 kelch-like protein 18 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Domain of unknown function (DUF3342)"	Kelch-like protein 18 GN=KLHL18 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 18 isoform X2 [Equus przewalskii]
ENSG00000114650(SCAP)	--	17.20256663	1452	16.45094124	1356	17.72641722	1522	18.06937349	1499	19.6315068	1600	16.59983458	1404	0.983800956	0.01511093	normal	0.960987967	0.217065103	normal	0.978295714	-0.124587936	normal	0.89954264	0.035351007	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[I]	Lipid transport and metabolism	"Sterol-sensing domain of SREBP cleavage-activation;; Patched family;; WD domain, G-beta repeat"	Sterol regulatory element-binding protein cleavage-activating protein GN=SCAP OS=Homo sapiens (Human) PE=1 SV=4	I	Lipid transport and metabolism	PREDICTED: sterol regulatory element-binding protein cleavage-activating protein isoform 1 [Ceratotherium simum simum]
ENSG00000114654(EFCC1)	--	0	0	0	0	0	0	0	0	0	0	0.0186811	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	EF-hand and coiled-coil domain-containing protein 1 GN=EFCC1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: EF-hand and coiled-coil domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000114656(KIAA1257)	--	0	0	0	0	0.0377821	1	0.039758117	2	0.0372461	1	0.024666058	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4550)	Uncharacterized protein KIAA1257 GN=KIAA1257 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein KIAA1257-like [Pteropus alecto]
ENSG00000114670(NEK11)	--	1.766513	92	2.040467	96	2.1382228	101	2.4994965	142	1.937302	101	2.568887	146	0.631176272	0.587402393	normal	0.969111873	0.051038547	normal	0.748984151	0.516850501	normal	0.31507974	0.407566634	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08857|0|ggo:101143809|NEK11; serine/threonine-protein kinase Nek11 isoform 1; K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase Nek11 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase Nek11 [Trichechus manatus latirostris]
ENSG00000114686(MRPL3)	--	45.95599455	1374	46.042862	1381	48.753816	1438	51.31088502	1544	51.69973729	1529	40.67062559	1223	0.976775372	0.137313587	normal	0.977752554	0.125318071	normal	0.949457734	-0.241654819	normal	0.967999994	0.013268508	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02906|0|hsa:11222|MRPL3, COXPD9, MRL3, RPML3; mitochondrial ribosomal protein L3; K02906 large subunit ribosomal protein L3 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L3	"39S ribosomal protein L3, mitochondrial GN=MRPL3 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L3, mitochondrial [Galeopterus variegatus]"
ENSG00000114698(PLSCR4)	--	6.242030063	263	5.571486299	253	7.346161593	246	9.239950655	311	9.577511037	366	8.189237848	351	0.94314554	0.209890968	normal	0.482894253	0.508738355	normal	0.505637016	0.50192507	normal	0.090822377	0.411123963	normal	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Scramblase	Phospholipid scramblase 4 GN=PLSCR4 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: phospholipid scramblase 4 isoform X1 [Galeopterus variegatus] 
ENSG00000114735(HEMK1)	--	3.649207346	347	2.671900012	331	4.157055912	353	3.531722	273	3.9037498	317	4.681792121	397	0.814810372	-0.374989832	normal	0.964169767	-0.083385593	normal	0.95580657	0.16053055	normal	0.815579992	-0.082900275	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K02493|0|hsa:51409|HEMK1, HEMK, MTQ1; HemK methyltransferase family member 1; K02493 release factor glutamine methyltransferase [EC:2.1.1.297] (A)"	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase small domain;; Methyltransferase domain;; Methyltransferase domain;; Conserved hypothetical protein 95;; Ribosomal protein L11 methyltransferase (PrmA);; Methyltransferase domain;; Putative RNA methylase family UPF0020;; Methyltransferase domain	HemK methyltransferase family member 1 GN=HEMK1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: hemK methyltransferase family member 1 [Galeopterus variegatus]
ENSG00000114737(CISH)	--	1.148503376	43	0.923883932	35	0.412812401	15	0.559128045	21	0.932382496	35	0.711459827	27	0.686111445	-1.011975074	normal	0.982116918	-0.020539115	normal	0.952255848	0.78035192	normal	0.866117036	-0.185774408	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	"K04701|2.73783e-170|hsa:1154|CISH, BACTS2, CIS, CIS-1, G18, SOCS; cytokine inducible SH2-containing protein; K04701 cytokine inducible SH2-containing protein (A)"	Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917)	[T]	Signal transduction mechanisms	SH2 domain;; SOCS box	Cytokine-inducible SH2-containing protein GN=CISH OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cytokine-inducible SH2-containing protein isoform X3 [Equus caballus] 
ENSG00000114738(MAPKAPK3)	--	19.50722	833	19.681351	842	21.178347	886	21.77881007	908	20.26272	875	20.208444	846	0.974273844	0.093378548	normal	0.976815959	0.033976364	normal	0.975680902	-0.074809789	normal	0.963806192	0.016504457	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K04444|0|hsa:7867|MAPKAPK3, 3PK, MAPKAP-K3, MAPKAP3, MAPKAPK-3, MK-3; mitogen-activated protein kinase-activated protein kinase 3 (EC:2.7.11.1); K04444 mitogen-activated protein kinase-activated protein kinase 3 [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; VEGF signaling pathway (ko04370)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	MAP kinase-activated protein kinase 3 GN=MAPKAPK3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: MAP kinase-activated protein kinase 3 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000114739(ACVR2B)	--	2.269970294	444	2.129422765	420	2.345085667	456	1.626317269	319	2.123922061	413	2.325041	454	0.426805123	-0.505760213	normal	0.9683381	-0.045508856	normal	0.970835938	-0.014584494	normal	0.518325555	-0.174433047	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K13596|0|hsa:93|ACVR2B, ACTRIIB, ActR-IIB, HTX4; activin A receptor, type IIB (EC:2.7.11.30); K13596 activin receptor type-2B [EC:2.7.11.30] (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Activin types I and II receptor domain	Activin receptor type-2B (Precursor) GN=ACVR2B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: activin receptor type-2B [Orcinus orca] 
ENSG00000114742(WDR48)	--	11.02118	798	12.57253	895	12.18679	849	12.08916001	876	12.29764006	886	12.61303008	904	0.972840977	0.103519592	normal	0.977209789	-0.035946495	normal	0.975334717	0.082124992	normal	0.871889951	0.047603464	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K15361|0|ssc:100518629|WDR48; WD repeat domain 48; K15361 WD repeat-containing protein 48 (A)	Fanconi anemia pathway (ko03460)	[S]	Function unknown	"Domain of unknown function (DUF3337);; WD domain, G-beta repeat"	WD repeat-containing protein 48 GN=WDR48 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: WD repeat-containing protein 48 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000114744(COMMD2)	--	10.496388	584	10.89899	606	10.985902	599	11.86531	670	12.441804	691	11.480246	640	0.959258147	0.166950176	normal	0.959158451	0.167549585	normal	0.97070092	0.087011904	normal	0.570902998	0.1402769	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 2 GN=COMMD2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: COMM domain-containing protein 2 [Galeopterus variegatus]
ENSG00000114745(GORASP1)	--	11.69851017	676	12.43116079	726	11.669937	677	14.22369339	856	17.13723135	956	15.38641914	895	0.885933957	0.309129735	normal	0.788537869	0.374932017	normal	0.734952242	0.393673205	normal	0.040334223	0.359719896	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	GRASP55/65 PDZ-like domain;; PDZ domain	Golgi reassembly-stacking protein 1 GN=GORASP1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi reassembly-stacking protein 1 isoform X2 [Mustela putorius furo] 
ENSG00000114757(PEX5L)	--	0.056066488	8	0.101486274	4	0.042144585	5	0.041707867	6	0.04738025	6	0.034650606	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3"	PEX5-related protein GN=PEX5L OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PEX5-related protein isoform 1 [Dasypus novemcinctus]
ENSG00000114767(RRP9)	--	16.9202	532	16.9208	552	19.908	650	15.6264	493	16.6035	517	14.8754	468	0.961974909	-0.140249946	normal	0.965339594	-0.115603208	normal	0.45421883	-0.480897938	normal	0.251337541	-0.251433215	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14793|0|hsa:9136|RRP9, RNU3IP2, U3-55K; ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); K14793 ribosomal RNA-processing protein 9 (A)"	--	[A]	RNA processing and modification	"WD domain, G-beta repeat"	U3 small nucleolar RNA-interacting protein 2 GN=RRP9 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U3 small nucleolar RNA-interacting protein 2 [Equus przewalskii]
ENSG00000114770(ABCC5)	--	7.535365807	803	8.880939434	869	8.625883192	902	7.530890015	770	7.7625458	735	9.493615003	896	0.973172614	-0.09119559	normal	0.926804589	-0.262541016	normal	0.978264554	-0.017890049	normal	0.606625381	-0.121019655	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05668|0|pps:100981748|ABCC5; ATP-binding cassette, sub-family C (CFTR/MRP), member 5; K05668 ATP-binding cassette, subfamily C (CFTR/MRP), member 5 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter;; ABC transporter transmembrane region;; RecF/RecN/SMC N terminal domain;; AAA domain	Multidrug resistance-associated protein 5 GN=ABCC5 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: multidrug resistance-associated protein 5 isoform X1 [Galeopterus variegatus]
ENSG00000114771(AADAC)	--	8.499650999	1316	10.28880403	1573	9.215656303	1318	14.01550084	2305	13.50537804	2073	16.35402444	2309	0.000572089	0.777081185	normal	0.821305509	0.376458727	normal	0.000287016	0.799923999	normal	3.88E-06	0.647136078	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K13616|0|hsa:13|AADAC, CES5A1, DAC; arylacetamide deacetylase (EC:3.1.1.3); K13616 arylacetamide deacetylase [EC:3.1.1.3] (A)"	--	[V]	Defense mechanisms	alpha/beta hydrolase fold;; Carboxylesterase family	Arylacetamide deacetylase GN=AADAC OS=Homo sapiens (Human) PE=1 SV=5	V	Defense mechanisms	PREDICTED: arylacetamide deacetylase isoform X1 [Equus caballus]
ENSG00000114784(EIF1B)	--	32.7447	393	40.6631	484	37.795	449	36.2518	442	34.5561	416	47.1914	570	0.960378235	0.138175239	normal	0.931598403	-0.239043534	normal	0.852716729	0.334951505	normal	0.812372923	0.086457305	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	K03113|1.23382e-65|ssc:414417|translation factor sui1-like protein; K03113 translation initiation factor 1 (A)	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Translation initiation factor SUI1	Eukaryotic translation initiation factor 1b GN=EIF1B OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	"Eukaryotic translation initiation factor 1b, partial [Bos mutus]"
ENSG00000114786(ABHD14A-ACY1)	--	20.77293596	470	20.788146	454	21.15261968	466	19.03696	428	20.31639273	405	20.72259313	400	0.955935808	-0.165315616	normal	0.950095042	-0.185542146	normal	0.936907669	-0.227822561	normal	0.453588915	-0.194293032	normal	[E]	Amino acid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	K14677|0|ptr:460414|ACY1; aminoacylase 1; K14677 aminoacylase [EC:3.5.1.14] (A)	Arginine and proline metabolism (ko00330);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Peptidase family M20/M25/M40;; Alpha/beta hydrolase family;; Peptidase dimerisation domain;; Alpha/beta hydrolase family;; Putative lysophospholipase	Aminoacylase-1 GN=ACY1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	Aminoacylase-1 [Myotis brandtii]
ENSG00000114790(ARHGEF26)	--	2.3406956	219	1.852116844	169	2.618478152	249	2.8179388	271	2.968782676	274	2.122569082	203	0.919574374	0.274794081	normal	0.134293603	0.670968211	normal	0.907574658	-0.300929601	normal	0.542395782	0.210313732	normal	[T]	Signal transduction mechanisms	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K13744|0|hsa:26084|ARHGEF26, CSGEF, HMFN1864, SGEF; Rho guanine nucleotide exchange factor (GEF) 26; K13744 SH3 domain-containing guanine exchange factor (A)"	Bacterial invasion of epithelial cells (ko05100)	[T]	Signal transduction mechanisms	RhoGEF domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; PH domain	Rho guanine nucleotide exchange factor 26 GN=ARHGEF26 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 26 isoform X1 [Pteropus alecto] 
ENSG00000114796(KLHL24)	--	3.277685502	250	6.223434905	504	3.8725758	306	3.98620945	318	4.937813702	424	10.5605036	848	0.889293515	0.314549026	normal	0.914944424	-0.2699018	normal	2.12E-13	1.457727079	up	0.585518535	0.566170825	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10461|0|pps:100980858|KLHL24; kelch-like family member 24; K10461 kelch-like protein 24/35 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Kelch-like protein 24 GN=KLHL24 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 24 isoform X5 [Canis lupus familiaris] 
ENSG00000114805(PLCH1)	--	2.96182311	399	2.7493158	352	3.0897175	403	5.0191608	662	5.485390454	731	4.407840086	595	0.014955734	0.697504707	normal	3.05E-06	1.029733983	up	0.219385882	0.552102895	normal	9.76E-06	0.763411588	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain;; EF-hand domain pair;; EF hand;; EF-hand domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 GN=PLCH1 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 [Galeopterus variegatus]"
ENSG00000114812(VIPR1)	--	1.259094621	64	2.07578354	94	2.020930424	62	0.579713646	21	0.472039993	25	0.859026445	22	0.004269918	-1.569456192	down	3.64E-06	-1.869671055	down	0.017532529	-1.441546886	normal	0.0001024	-1.715370443	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	K04589|0|pps:100977630|VIPR1; vasoactive intestinal peptide receptor 1; K04589 vasoactive intestinal peptide receptor 1 (A)	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Vasoactive intestinal polypeptide receptor 1 (Precursor) GN=VIPR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vasoactive intestinal polypeptide receptor 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000114841(DNAH1)	--	0.449161741	84	0.3776048	78	0.534651005	107	0.148186536	47	0.622043504	138	0.236326018	76	0.396063449	-0.847537771	normal	0.185883559	0.790035779	normal	0.851917627	-0.493514259	normal	0.960416065	-0.062752465	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:25981|DNAH1, DNAHC1, HDHC7, HL-11, HL11, HSRF-1, XLHSRF-1; dynein, axonemal, heavy chain 1; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D4;; ATP-binding dynein motor region D5;; Microtubule-binding stalk of dynein motor;; P-loop containing dynein motor region D3;; AAA domain (dynein-related subfamily);; AAA domain;; ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA ATPase domain;; AAA domain;; Type II/IV secretion system protein;; RNA helicase"	"Dynein heavy chain 1, axonemal GN=DNAH1 OS=Homo sapiens (Human) PE=2 SV=4"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 1, axonemal [Equus caballus]"
ENSG00000114850(SSR3)	--	78.15767517	3278	80.52350012	3174	89.87159308	3161	82.90226187	3810	74.57682727	3267	71.40164021	3309	0.982585174	0.186061934	normal	0.990385388	0.020228269	normal	0.990117905	0.057695834	normal	0.693810868	0.089883124	normal	--	--	Biological Process: SRP-dependent cotranslational protein targeting to membrane (GO:0006614);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13251|2.21767e-129|ptr:460799|SSR3; signal sequence receptor, gamma (translocon-associated protein gamma); K13251 translocon-associated protein subunit gamma (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Translocon-associated protein, gamma subunit (TRAP-gamma)"	Translocon-associated protein subunit gamma GN=SSR3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	hypothetical protein M91_11447 [Bos mutus]
ENSG00000114853(ZBTB47)	--	3.081746223	307	2.792830694	282	2.565972206	288	3.516539423	358	4.093067979	419	3.233331708	337	0.948470428	0.190007466	normal	0.319802606	0.547405805	normal	0.940599534	0.217332355	normal	0.194604233	0.323817104	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10518|0|pon:100938526|ZBTB47; zinc finger and BTB domain containing 47; K10518 zinc finger and BTB domain-containing protein 47 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; BTB/POZ domain;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 47 GN=ZBTB47 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 652 [Odobenus rosmarus divergens]
ENSG00000114854(TNNC1)	--	0.98215007	11	1.56069116	18	2.241333408	26	0.340274164	4	0.261491083	2	1.234591482	14	--	--	--	--	--	--	0.947350776	-0.834324042	normal	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K05865|7.14723e-101|ptr:746369|TNNC1; troponin C type 1 (slow); K05865 troponin C, slow skeletal and cardiac muscles (A)"	Calcium signaling pathway (ko04020);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain;; Cytoskeletal-regulatory complex EF hand;; Secreted protein acidic and rich in cysteine Ca binding region	"Troponin C, slow skeletal and cardiac muscles GN=TNNC1 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: troponin C, slow skeletal and cardiac muscles [Felis catus] "
ENSG00000114857(NKTR)	--	8.6312974	1249	8.636084	1341	8.575019	1230	8.347177	1265	8.527378	1191	9.799648	1310	0.982092984	-0.012453134	normal	0.96466837	-0.192332065	normal	0.979911246	0.082518731	normal	0.88178324	-0.041759452	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K12740|0|hsa:4820|NKTR, p104; natural killer cell triggering receptor (EC:5.2.1.8); K12740 NK-tumor recognition protein (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Putative peptidyl-prolyl cis-trans isomerase GN=NKTR OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NK-tumor recognition protein [Ceratotherium simum simum]
ENSG00000114859(CLCN2)	--	2.401834752	149	1.81699665	111	1.57917848	98	1.18637266	74	1.589381	95	0.95114584	60	0.007019901	-1.025229064	down	0.952011429	-0.242412722	normal	0.587440891	-0.702126558	normal	0.078524236	-0.666587449	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05011|0|pps:100973795|CLCN2; chloride channel, voltage-sensitive 2; K05011 chloride channel 2 (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	Chloride channel protein 2 GN=CLCN2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: chloride channel protein 2 isoform X1 [Sus scrofa]
ENSG00000114861(FOXP1)	--	6.07685505	426	7.27979589	393	8.666280904	429	12.31563993	946	12.84023425	901	10.3452914	905	4.48E-08	1.117382098	up	1.35E-08	1.172508794	up	2.89E-07	1.066002195	up	4.44E-13	1.119628642	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09409|0|pps:100994798|FOXP1; forkhead box P1; K09409 forkhead box protein P (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein P1 GN=FOXP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein P1 isoform X1 [Galeopterus variegatus]
ENSG00000114867(EIF4G1)	--	73.40138018	9258	74.73450699	9636	77.97859335	9923	88.25682873	10904	84.94302849	10551	75.68168138	9349	0.990972202	0.205221328	normal	0.995056173	0.109430468	normal	0.995325128	-0.094240938	normal	0.778559888	0.074651182	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	"K03260|0|hsa:1981|EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18; eukaryotic translation initiation factor 4 gamma, 1; K03260 translation initiation factor 4G (A)"	RNA transport (ko03013);; Viral myocarditis (ko05416)	[J]	"Translation, ribosomal structure and biogenesis"	MIF4G domain;; MA3 domain;; eIF4-gamma/eIF5/eIF2-epsilon	Eukaryotic translation initiation factor 4 gamma 1 GN=EIF4G1 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4 gamma 1 isoform X2 [Galeopterus variegatus]
ENSG00000114902(SPCS1)	--	87.251459	867	94.424386	928	88.459611	872	102.484426	1030	105.599223	1030	102.513944	1012	0.951565567	0.217354461	normal	0.97175306	0.128821743	normal	0.955447467	0.206185598	normal	0.36710422	0.182660752	normal	--	--	Cellular Component: signal peptidase complex (GO:0005787);; Biological Process: signal peptide processing (GO:0006465);; Molecular Function: peptidase activity (GO:0008233);; Cellular Component: integral component of membrane (GO:0016021);; 	"K12946|6.81448e-103|hsa:28972|SPCS1, SPC1, SPC12, YJR010C-A; signal peptidase complex subunit 1 homolog (S. cerevisiae) (EC:3.4.-.-); K12946 signal peptidase complex subunit 1 [EC:3.4.-.-] (A)"	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Microsomal signal peptidase 12 kDa subunit (SPC12)	Signal peptidase complex subunit 1 GN=SPCS1 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal peptidase complex subunit 1 [Trichechus manatus latirostris]
ENSG00000114904(NEK4)	--	6.562751204	568	6.233402	521	8.009650013	687	7.204641573	616	6.592515832	562	7.73716	617	0.970134874	0.085983791	normal	0.968366248	0.087615303	normal	0.960824648	-0.162952345	normal	0.990268586	-0.005425025	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08857|0|pps:100981661|NEK4; NIMA-related kinase 4; K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)	--	--	--	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase Nek4 GN=NEK4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Nek4 [Ceratotherium simum simum]
ENSG00000114923(SLC4A3)	--	1.633932816	147	1.696555512	156	1.239132834	112	0.84107298	75	1.113287298	96	1.095791426	87	0.012878126	-0.986961198	normal	0.263244344	-0.712965994	normal	0.92118947	-0.367064197	normal	0.042184582	-0.70693634	normal	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13856|0|ptr:459969|SLC4A3; solute carrier family 4 (anion exchanger), member 3; K13856 solute carrier family 4 (anion exchanger), member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	HCO3- transporter family;; Band 3 cytoplasmic domain	Anion exchange protein 3 GN=SLC4A3 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: anion exchange protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000114933(INO80D)	--	2.064440793	462	2.599382952	574	2.084947106	457	1.47304028	331	1.73029478	387	1.8655984	420	0.403239563	-0.509880206	normal	0.144131089	-0.588243206	normal	0.962240471	-0.129648603	normal	0.046241193	-0.412432946	normal	--	--	--	K11668|0|hsa:54891|INO80D; INO80 complex subunit D; K11668 INO80 complex subunit D (A)	--	--	--	Potential DNA-binding domain;; Primase zinc finger	INO80 complex subunit D GN=INO80D OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: INO80 complex subunit D isoform X1 [Galeopterus variegatus]
ENSG00000114942(EEF1B2)	--	527.3033	6287	477.483538	5877	506.5606793	6244	432.3176	5314	410.5239	4903	391.2314	4728	0.972649366	-0.273333036	normal	0.968393325	-0.282761908	normal	0.830086727	-0.409417607	normal	0.054817766	-0.322164549	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation elongation factor activity (GO:0003746);; Biological Process: translational elongation (GO:0006414);; 	K03232|1.29147e-126|ptr:736151|EEF1B2; eukaryotic translation elongation factor 1 beta 2; K03232 elongation factor 1-beta (A)	--	[K]	Transcription	EF-1 guanine nucleotide exchange domain;; Eukaryotic elongation factor 1 beta central acidic region	Elongation factor 1-beta GN=EEF1B2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: elongation factor 1-beta [Dasypus novemcinctus]
ENSG00000114948(ADAM23)	--	10.49311975	909	14.96814543	960	10.48930904	812	1.751126056	159	2.33983137	207	2.362450307	205	0	-2.534474367	down	0	-2.226504887	down	0	-1.986189883	down	6.73E-43	-2.251846793	down	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K06837|0|hsa:8745|ADAM23, MDC-3, MDC3; ADAM metallopeptidase domain 23; K06837 disintegrin and metalloproteinase domain-containing protein 23 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Reprolysin family propeptide;; Disintegrin;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 23 (Precursor) GN=ADAM23 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 23 [Loxodonta africana]
ENSG00000114956(DGUOK)	--	65.68716	859	57.56799	793	71.19213	932	54.48972	768	51.30056	677	60.51319	818	0.956933891	-0.192020593	normal	0.932747021	-0.249076877	normal	0.957163871	-0.196180507	normal	0.292798298	-0.212191723	normal	--	--	--	"K00904|0|hsa:1716|DGUOK, MTDPS3, dGK; deoxyguanosine kinase (EC:2.7.1.113); K00904 deoxyguanosine kinase [EC:2.7.1.113] (A)"	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	Deoxynucleoside kinase;; AAA domain	"Deoxyguanosine kinase, mitochondrial (Precursor) GN=DGUOK OS=Homo sapiens (Human) PE=1 SV=2"	F	Nucleotide transport and metabolism	"PREDICTED: deoxyguanosine kinase, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000114978(MOB1A)	--	70.3468	4676	75.2061	4963	71.4356	4638	62.2286	4179	60.4915	4025	51.894	3467	0.984459391	-0.192882347	normal	0.942200582	-0.323540529	normal	0.743803596	-0.427944443	normal	0.059113826	-0.312563629	normal	--	--	--	K06685|2.38348e-162|umr:103671401|MOB1A; MOB kinase activator 1A; K06685 MOB kinase activator 1 (A)	Hippo signaling pathway (ko04390)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mob1/phocein family	MOB kinase activator 1A GN=MOB1A OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: MOB kinase activator 1A [Loxodonta africana] 
ENSG00000114982(KANSL3)	--	12.511846	1296	13.835775	1444	11.66000461	1241	11.14717438	1156	11.177631	1181	12.465394	1315	0.96337774	-0.195510986	normal	0.902235743	-0.311127346	normal	0.980413731	0.075179234	normal	0.484059674	-0.14544928	normal	--	--	--	K16719|0|pps:100979512|KANSL3; KAT8 regulatory NSL complex subunit 3; K16719 regulatory NSL complex subunit 3 (A)	--	[R]	General function prediction only	Alpha/beta hydrolase family	KAT8 regulatory NSL complex subunit 3 GN=KANSL3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: KAT8 regulatory NSL complex subunit 3 isoform X2 [Ailuropoda melanoleuca]
ENSG00000114988(LMAN2L)	--	18.768984	781	19.119965	805	18.797046	785	15.379463	639	14.522632	597	14.665297	609	0.872397902	-0.319642289	normal	0.561045174	-0.451695046	normal	0.783180343	-0.373722174	normal	0.032443735	-0.383254814	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K10083|0|hsa:81562|LMAN2L, VIPL; lectin, mannose-binding 2-like; K10083 lectin, mannose-binding 2-like (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Legume-like lectin family	VIP36-like protein (Precursor) GN=LMAN2L OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: VIP36-like protein isoform X1 [Oryctolagus cuniculus]
ENSG00000114993(RTKN)	--	11.69789357	472	10.02969518	425	10.89700636	429	6.285210746	286	6.412279166	271	6.858423843	284	0.009040814	-0.75043044	normal	0.060071065	-0.667595139	normal	0.153995141	-0.600756498	normal	0.000756544	-0.678190928	normal	--	--	--	--	--	--	--	Cell division protein anillin;; PH domain;; Hr1 repeat	Rhotekin OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rhotekin isoform X1 [Leptonychotes weddellii]
ENSG00000114999(TTL)	--	5.52752613	1551	4.989542003	1390	5.595865752	1550	5.0946591	1428	4.95325149	1378	4.403710458	1232	0.975474899	-0.14988017	normal	0.982429082	-0.033898512	normal	0.866863182	-0.339185354	normal	0.366084769	-0.174890013	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	K06047|0|pps:100969421|TTL; tubulin tyrosine ligase; K06047 tubulin---tyrosine ligase [EC:6.3.2.25] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin--tyrosine ligase GN=TTL OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin--tyrosine ligase [Camelus dromedarius]
ENSG00000115008(IL1A)	--	0.321264	11	0.0296191	1	0.0588189	1	0.290125	10	0.705912	24	0.173502	6	--	--	--	0.002757646	3.329789018	up	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Molecular Function: interleukin-1 receptor binding (GO:0005149);; Cellular Component: extracellular space (GO:0005615);; Biological Process: inflammatory response (GO:0006954);; Biological Process: immune response (GO:0006955);; 	"K04383|0|ptr:470485|IL1A; interleukin 1, alpha; K04383 interleukin 1 alpha (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Hematopoietic cell lineage (ko04640);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Type I diabetes mellitus (ko04940);; Prion diseases (ko05020);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323);; Graft-versus-host disease (ko05332)	--	--	Interleukin-1 propeptide;; Interleukin-1 / 18	Interleukin-1 alpha (Precursor) GN=IL1A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-1 alpha [Vicugna pacos]
ENSG00000115009(CCL20)	--	1.640528	16	3.514816	33	0.504195	4	0.299446585	3	0.409603652	3	6.86217	67	--	--	--	0.000313429	-2.952549491	down	5.91E-11	3.628577332	up	--	--	--	--	--	--	K14625|6.80064e-53|ggo:101135965|CCL20; c-C motif chemokine 20; K14625 C-C motif chemokine 20 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; TNF signaling pathway (ko04668);; Rheumatoid arthritis (ko05323)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	CCL20(2-70) (Precursor) GN=CCL20 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: c-C motif chemokine 20 isoform X1 [Camelus ferus] 
ENSG00000115020(PIKFYVE)	--	7.922043286	1251	8.717365	1388	8.831679267	1471	4.62196602	796	4.76990661	772	5.377512416	886	0.00992861	-0.682013862	normal	8.12E-05	-0.866476429	normal	0.002141564	-0.738720794	normal	9.43E-08	-0.764716619	normal	--	--	Molecular Function: ATP binding (GO:0005524);; Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: intracellular signal transduction (GO:0035556);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; Molecular Function: metal ion binding (GO:0046872);; 	"K00921|0|pps:100981447|PIKFYVE; phosphoinositide kinase, FYVE finger containing; K00921 1-phosphatidylinositol-3-phosphate 5-kinase [EC:2.7.1.150] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Phagosome (ko04145);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	"Phosphatidylinositol-4-phosphate 5-Kinase;; TCP-1/cpn60 chaperonin family;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; FYVE zinc finger"	1-phosphatidylinositol 3-phosphate 5-kinase GN=PIKFYVE OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: 1-phosphatidylinositol 3-phosphate 5-kinase [Felis catus]
ENSG00000115041(KCNIP3)	--	0.519178014	34	0.4018417	24	0.532156908	29	0.214238424	14	0.373108378	23	0.169244302	9	0.635778544	-1.22228299	normal	0.986337265	-0.077817716	normal	0.435382595	-1.544803284	normal	0.156423173	-0.94111696	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand;; Secreted protein acidic and rich in cysteine Ca binding region;; Cytoskeletal-regulatory complex EF hand	Calsenilin GN=KCNIP3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: calsenilin isoform X1 [Chrysochloris asiatica]
ENSG00000115042(FAHD2A)	--	20.03908531	596	15.72031236	468	19.81757338	559	13.23401569	395	10.76665628	352	11.82189855	341	0.071394846	-0.622306092	normal	0.673657789	-0.430748773	normal	0.012508377	-0.718852205	normal	0.0015294	-0.598507027	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	Fumarylacetoacetate (FAA) hydrolase family	Fumarylacetoacetate hydrolase domain-containing protein 2A GN=FAHD2A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: fumarylacetoacetate hydrolase domain-containing protein 2A [Camelus ferus] 
ENSG00000115053(NCL)	--	206.4491072	18156	232.7566135	20763	217.5963071	19270	174.2780628	14787	169.6644527	14431	129.6672077	11335	0.97638899	-0.32691855	normal	0.462718752	-0.546222188	normal	0.001189542	-0.773783493	normal	0.001228852	-0.542898102	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K11294|0|pps:100987584|NCL; nucleolin; K11294 nucleolin (A)	--	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Limkain b1"	Nucleolin GN=NCL OS=Homo sapiens (Human) PE=1 SV=3	AJ	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	PREDICTED: nucleolin [Felis catus]
ENSG00000115073(ACTR1B)	--	25.1869	1005	22.248	917	22.8025	939	18.0368	727	17.5685	699	17.9779	722	0.348933859	-0.497102562	normal	0.69142338	-0.412274455	normal	0.753302556	-0.386705384	normal	0.008529688	-0.434771053	normal	[Z]	Cytoskeleton	--	"K16575|0|pps:100971719|ACTR1B; ARP1 actin-related protein 1 homolog B, centractin beta (yeast); K16575 centractin (A)"	--	[Z]	Cytoskeleton	Actin	Beta-centractin GN=ACTR1B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: beta-centractin [Camelus bactrianus] 
ENSG00000115084(SLC35F5)	--	27.83282429	1890	27.51982649	1932	23.184052	1825	20.77722552	1509	19.14690602	1343	22.65080357	1584	0.850356345	-0.355301636	normal	0.190045435	-0.545547121	normal	0.965330025	-0.212426456	normal	0.017553552	-0.369409796	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15289|0|hsa:80255|SLC35F5; solute carrier family 35, member F5; K15289 solute carrier family 35, member F5 (A)"	--	[S]	Function unknown	EamA-like transporter family	Solute carrier family 35 member F5 GN=SLC35F5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: solute carrier family 35 member F5 [Eptesicus fuscus]
ENSG00000115091(ACTR3)	--	117.0104058	5234	124.4435153	5713	116.047256	5373	110.0569822	5249	95.73883809	4308	83.79431017	3947	0.993586625	-0.026695765	normal	0.781957778	-0.428525731	normal	0.667264786	-0.45311335	normal	0.08272704	-0.295406518	normal	[Z]	Cytoskeleton	--	K18584|0|ptr:459563|ACTR3; ARP3 actin-related protein 3 homolog (yeast); K18584 actin-related protein 3 (A)	--	[Z]	Cytoskeleton	Actin	Actin-related protein 3 GN=ACTR3 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: actin-related protein 3-like isoform 1 [Ceratotherium simum simum]
ENSG00000115107(STEAP3)	--	38.0806055	2738	29.747764	2253	33.93607196	2597	24.396321	1799	23.88760507	1712	21.92198036	1547	0.025161718	-0.636315448	normal	0.719703606	-0.417268752	normal	0.00103862	-0.75508803	normal	1.64E-05	-0.606670399	normal	[R]	General function prediction only	--	"K10142|0|nle:100604205|STEAP3; STEAP family member 3, metalloreductase; K10142 metalloreductase STEAP3 [EC:1.16.1.-] (A)"	p53 signaling pathway (ko04115)	--	--	Ferric reductase like transmembrane component;; NADP oxidoreductase coenzyme F420-dependent;; NAD binding domain of 6-phosphogluconate dehydrogenase	Metalloreductase STEAP3 GN=STEAP3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: metalloreductase STEAP3 [Ceratotherium simum simum]
ENSG00000115109(EPB41L5)	--	5.63399142	442	4.4436545	404	4.667879512	425	2.409913086	245	2.776272815	248	1.893103551	187	0.00068582	-0.877934421	normal	0.025837442	-0.721956434	normal	3.55E-07	-1.186172222	down	4.43E-06	-0.924226441	normal	--	--	--	--	--	[R]	General function prediction only	FERM C-terminal PH-like domain;; FERM central domain;; FERM N-terminal domain;; FERM adjacent (FA)	Band 4.1-like protein 5 GN=EPB41L5 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: band 4.1-like protein 5 isoform 1 [Ceratotherium simum simum]
ENSG00000115112(TFCP2L1)	--	0.638508348	102	0.58624041	95	0.278620097	44	1.272002567	203	1.178192831	188	0.840491578	133	0.005061909	0.95173132	normal	0.007688628	0.952333643	normal	5.87E-06	1.555302866	up	0.004873082	1.096985739	up	--	--	--	"K09275|0|hsa:29842|TFCP2L1, CRTR1, LBP-9, LBP9; transcription factor CP2-like 1; K09275 transcription factor CP2 and related proteins (A)"	--	[K]	Transcription	CP2 transcription factor	Transcription factor CP2-like protein 1 GN=TFCP2L1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor CP2-like protein 1 [Trichechus manatus latirostris]
ENSG00000115128(SF3B6)	--	88.0471	910	86.1297	896	74.9398	782	71.2021	758	65.6815	679	56.6205	594	0.90287495	-0.293956231	normal	0.665386062	-0.420695177	normal	0.70724004	-0.404097536	normal	0.034864516	-0.371817705	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12833|1.44642e-76|umr:103671691|SF3B6; splicing factor 3b, subunit 6, 14kDa; K12833 pre-mRNA branch site protein p14 (A)"	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing factor 3B subunit 6 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pre-mRNA branch site protein p14-like [Bos mutus] 
ENSG00000115129(TP53I3)	--	50.898626	1323	57.46913939	1628	62.221617	1588	73.55556	1917	72.131644	1872	69.27267	1794	0.322134259	0.503716583	normal	0.972977545	0.179897241	normal	0.974791582	0.167527351	normal	0.09722171	0.277374708	normal	[CR]	Energy production and conversion;; General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	K10133|0|pps:100967848|TP53I3; tumor protein p53 inducible protein 3; K10133 tumor protein p53-inducible protein 3 [EC:1.-.-.-] (A)	p53 signaling pathway (ko04115)	[CR]	Energy production and conversion;; General function prediction only	Zinc-binding dehydrogenase;; Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	Quinone oxidoreductase PIG3 GN=TP53I3 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: quinone oxidoreductase PIG3 [Balaenoptera acutorostrata scammoni]
ENSG00000115137(DNAJC27)	--	1.937123238	146	1.792221392	146	1.481309578	111	1.320672056	107	1.70739218	141	1.486842898	117	0.807225329	-0.473345197	normal	0.965219159	-0.070951862	normal	0.96853473	0.066771262	normal	0.738075303	-0.164164423	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; DnaJ domain;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	DnaJ homolog subfamily C member 27 GN=DNAJC27 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: dnaJ homolog subfamily C member 27 [Tupaia chinensis]
ENSG00000115145(STAM2)	--	9.226995	783	9.599468	786	9.195449	755	6.079044511	525	7.0374196	601	6.34047087	545	0.072953826	-0.606064133	normal	0.7059359	-0.407690864	normal	0.451338938	-0.477381264	normal	0.003755241	-0.496983188	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; 	"K04705|0|hsa:10254|STAM2, Hbp, STAM2A, STAM2B; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; K04705 signal transducing adaptor molecule (A)"	Endocytosis (ko04144);; Jak-STAT signaling pathway (ko04630)	[T]	Signal transduction mechanisms	VHS domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Ubiquitin interaction motif	Signal transducing adapter molecule 2 GN=STAM2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: signal transducing adapter molecule 2 [Leptonychotes weddellii]
ENSG00000115155(OTOF)	--	0.009182583	1	0.024046135	4	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	C2 domain;; FerB (NUC096) domain;; FerI (NUC094) domain	Otoferlin GN=OTOF OS=Homo sapiens (Human) PE=1 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: otoferlin isoform X2 [Elephantulus edwardii]
ENSG00000115159(GPD2)	--	12.732357	1249	16.58369578	1604	14.27948722	1395	13.71023601	1212	12.4450629	1214	12.12986805	1064	0.979970953	-0.074123471	normal	0.675113415	-0.422872366	normal	0.732117743	-0.398562105	normal	0.073468087	-0.305189982	normal	[C]	Energy production and conversion	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00111|0|ptr:459670|GPD2; glycerol-3-phosphate dehydrogenase 2 (mitochondrial); K00111 glycerol-3-phosphate dehydrogenase [EC:1.1.5.3] (A)	Glycerophospholipid metabolism (ko00564)	[C]	Energy production and conversion	FAD dependent oxidoreductase;; EF-hand domain pair;; EF hand;; EF-hand domain;; FAD binding domain;; FAD dependent oxidoreductase;; Glucose inhibited division protein A;; Pyridine nucleotide-disulphide oxidoreductase	"Glycerol-3-phosphate dehydrogenase, mitochondrial (Precursor) GN=GPD2 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: glycerol-3-phosphate dehydrogenase, mitochondrial-like isoform X1 [Tupaia chinensis] "
ENSG00000115163(CENPA)	--	28.21728	715	27.67618	685	22.06085	564	19.31885	515	20.3108	496	22.18079	545	0.354753238	-0.502923268	normal	0.444174553	-0.485923777	normal	0.971441782	-0.057573322	normal	0.064462578	-0.357355446	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11495|3.89483e-56|ptr:459086|CENPA; centromere protein A; K11495 histone H3-like centromeric protein A (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3-like centromeric protein A GN=CENPA OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone H3-like centromeric protein A [Oryctolagus cuniculus]
ENSG00000115165(CYTIP)	--	0.081062184	3	0.278625037	2	0	0	0	0	0.0263656	0	0.026798941	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF)	Cytohesin-interacting protein GN=CYTIP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cytohesin-interacting protein [Equus caballus]
ENSG00000115170(ACVR1)	--	10.59540013	560	12.06098409	643	12.61338474	624	7.789960586	395	7.583025534	413	8.639813806	459	0.28544188	-0.532656508	normal	0.03843362	-0.658155327	normal	0.572980027	-0.450066378	normal	0.002643762	-0.5487607	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K04675|0|pon:100455728|ACVR1; activin A receptor, type I; K04675 activin receptor type-1 [EC:2.7.11.30] (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Transforming growth factor beta type I GS-motif;; Activin types I and II receptor domain	Activin receptor type-1 (Precursor) GN=ACVR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: activin receptor type-1 [Vicugna pacos]
ENSG00000115183(TANC1)	--	7.889428	1266	7.207205502	1156	7.370491005	1176	5.738818873	922	5.650250091	892	4.643777539	748	0.381737376	-0.487574345	normal	0.745420822	-0.394862462	normal	0.01782277	-0.659995832	normal	0.000852249	-0.511731711	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Protein TANC1 GN=TANC1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein TANC1 isoform X1 [Equus caballus] 
ENSG00000115194(SLC30A3)	--	2.821952271	110	2.249107958	83	3.439824183	92	1.009571648	36	1.449220855	62	1.569587541	61	1.89E-05	-1.601139401	down	0.917942313	-0.433105143	normal	0.79576667	-0.58914025	normal	0.034009617	-0.861577634	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14690|0|pon:100444428|SLC30A3; solute carrier family 30 (zinc transporter), member 3; K14690 solute carrier family 30 (zinc transporter), member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	Cation efflux family	Zinc transporter 3 GN=SLC30A3 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter 3 [Galeopterus variegatus]
ENSG00000115204(MPV17)	--	49.900128	672	50.12762601	712	45.94795816	638	38.920252	532	33.294241	435	43.78355866	608	0.797252312	-0.366921874	normal	0.007470515	-0.730282743	normal	0.971502038	-0.077588126	normal	0.042832022	-0.381457257	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K13348|3.04469e-121|pon:100442722|MPV17; MpV17 mitochondrial inner membrane protein; K13348 protein Mpv17 (A)	Peroxisome (ko04146)	[R]	General function prediction only	Mpv17 / PMP22 family	Protein Mpv17 GN=MPV17 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	Protein Mpv17 [Bos mutus]
ENSG00000115207(GTF3C2)	--	34.60150921	2114	34.87491954	2308	32.438862	2127	26.65879965	1643	27.02045629	1702	27.54756687	1807	0.770522459	-0.394149217	normal	0.555224297	-0.4604859	normal	0.958342864	-0.243327048	normal	0.017767088	-0.367129019	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15200|0|hsa:2976|GTF3C2, TFIIIC-BETA, TFIIIC110; general transcription factor IIIC, polypeptide 2, beta 110kDa; K15200 general transcription factor 3C polypeptide 2 (A)"	--	--	--	"WD domain, G-beta repeat"	General transcription factor 3C polypeptide 2 GN=GTF3C2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: general transcription factor 3C polypeptide 2 [Ursus maritimus]
ENSG00000115211(EIF2B4)	--	23.15855463	805	24.04178341	853	22.49047403	806	17.22264652	597	17.64577766	615	15.59263075	541	0.507362703	-0.461063932	normal	0.399809449	-0.492352906	normal	0.111582707	-0.58210052	normal	0.002265563	-0.512676879	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: cellular metabolic process (GO:0044237);; 	"K03680|0|ptr:459099|EIF2B4; eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; K03680 translation initiation factor eIF-2B subunit delta (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Initiation factor 2 subunit family	Translation initiation factor eIF-2B subunit delta GN=EIF2B4 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: translation initiation factor eIF-2B subunit delta isoform X1 [Capra hircus]
ENSG00000115216(NRBP1)	--	57.15285703	2874	55.67206385	2852	54.37661054	2739	46.193413	2329	48.61889998	2439	43.83556301	2235	0.905074837	-0.333982908	normal	0.964340018	-0.246969001	normal	0.933756624	-0.30148127	normal	0.07124334	-0.294888127	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08875|0|bacu:103018644|NRBP1; nuclear receptor binding protein 1; K08875 nuclear receptor-binding protein (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Nuclear receptor-binding protein GN=NRBP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: nuclear receptor-binding protein isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000115221(ITGB6)	--	0.101048779	7	0.192561232	12	0.187194691	12	2.221101281	183	2.348417302	193	1.543875492	121	0	4.406194349	up	0	3.82737343	up	7.77E-16	3.172806306	up	2.10E-17	3.981031908	up	--	--	--	"K06589|0|hsa:3694|ITGB6; integrin, beta 6; K06589 integrin beta 6 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; Integrin beta cytoplasmic domain;; Integrin beta tail domain;; EGF-like domain"	Integrin beta-6 (Precursor) GN=ITGB6 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin beta-6 isoform X1 [Condylura cristata]
ENSG00000115226(FNDC4)	--	1.39015037	44	1.365573	43	1.306819	40	0.843821	25	1.590172316	50	0.889535	27	0.854502081	-0.808465492	normal	0.974914009	0.189964892	normal	0.95374855	-0.549875161	normal	0.641539133	-0.337055952	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain	Fibronectin type III domain-containing protein 4 (Precursor) GN=FNDC4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: fibronectin type III domain-containing protein 4 [Orycteropus afer afer]
ENSG00000115232(ITGA4)	--	3.0755031	239	2.283154186	178	3.430793381	221	1.268674149	99	2.315493814	180	1.015212785	79	2.22E-06	-1.289034845	down	0.965959394	-0.005262433	normal	9.00E-08	-1.474789507	down	0.033701583	-0.85474858	normal	--	--	--	"K06483|0|hsa:3676|ITGA4, CD49D, IA4; integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor); K06483 integrin alpha 4 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Hematopoietic cell lineage (ko04640);; Leukocyte transendothelial migration (ko04670);; Intestinal immune network for IgA production (ko04672);; Regulation of actin cytoskeleton (ko04810);; Leishmaniasis (ko05140);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Integrin alpha-4 (Precursor) GN=ITGA4 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: integrin alpha-4 [Ceratotherium simum simum]
ENSG00000115233(PSMD14)	--	96.0045	2606	95.73225	2719	112.0153	2872	67.63921	1948	64.1327	1818	54.15211	1605	0.587569152	-0.450367316	normal	0.068140288	-0.601738248	normal	5.81E-05	-0.84716856	normal	6.54E-06	-0.631535271	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03030|0|umr:103659502|PSMD14; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; K03030 26S proteasome regulatory subunit N11 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Maintenance of mitochondrial structure and function;; Prokaryotic homologs of the JAB domain	26S proteasome non-ATPase regulatory subunit 14 GN=PSMD14 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 14 [Erinaceus europaeus]
ENSG00000115234(SNX17)	--	78.27629	2924	78.90985	3002	81.17685	3093	63.79292	2390	67.34136	2490	67.63449	2527	0.919246121	-0.321577673	normal	0.945624795	-0.291043538	normal	0.939562093	-0.299710198	normal	0.059794652	-0.305014885	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17929|0|mcf:102117871|SNX17; sorting nexin 17; K17929 sorting nexin-17 (A)	--	[RTU]	"General function prediction only;; Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PX domain	Sorting nexin-17 GN=SNX17 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-17 isoform X1 [Myotis lucifugus]
ENSG00000115239(ASB3)	--	9.894939	353	9.793449663	349	10.434792	368	9.359728	333	8.339934815	297	8.565366813	307	0.962354057	-0.114465196	normal	0.925100365	-0.253000763	normal	0.917429893	-0.268548542	normal	0.453093931	-0.212877792	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10325|0|ggo:101127925|ASB3; ankyrin repeat and SOCS box protein 3 isoform 1; K10325 ankyrin repeat and SOCS box protein 3 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 3 GN=ASB3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 3 isoform X2 [Mustela putorius furo] 
ENSG00000115241(PPM1G)	--	83.6772	4380	80.39	4291	90.8409	4830	79.4312	4159	76.0088	3926	63.4843	3310	0.990648253	-0.105488467	normal	0.987632997	-0.149625133	normal	0.189047443	-0.55327287	normal	0.123036168	-0.266307132	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K17499|0|ptr:470340|PPM1G; protein phosphatase, Mg2+/Mn2+ dependent, 1G (EC:3.1.3.16); K17499 protein phosphatase 1G [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C	Protein phosphatase 1G GN=PPM1G OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1G isoform X1 [Oryctolagus cuniculus]
ENSG00000115252(PDE1A)	--	0.013055486	1	0.071015894	3	0.084611562	2	0.245150312	13	0.372557	14	0.266754274	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13755|0|pon:100189722|PDE1A, DKFZP459K071; phosphodiesterase 1A, calmodulin-dependent (EC:3.1.4.17); K13755 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17] (A)"	Purine metabolism (ko00230);; Calcium signaling pathway (ko04020);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; 3'5'-cyclic nucleotide phosphodiesterase N-terminal	"Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A GN=PDE1A OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A isoform X4 [Oryctolagus cuniculus] "
ENSG00000115255(REEP6)	--	10.31530296	284	8.817132001	247	9.224381591	263	9.230773086	256	10.057617	279	6.01611336	168	0.951136206	-0.179555614	normal	0.955077464	0.153443171	normal	0.174433135	-0.650175639	normal	0.575552504	-0.197791951	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K17279|5.45541e-133|hsa:92840|REEP6, C19orf32, DP1L1, TB2L1; receptor accessory protein 6; K17279 receptor expression-enhancing protein 5/6 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"TB2/DP1, HVA22 family"	Receptor expression-enhancing protein 6 GN=REEP6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: receptor expression-enhancing protein 6 [Physeter catodon]
ENSG00000115257(PCSK4)	--	2.7854268	100	2.289184888	70	3.81028088	96	0.839276382	41	0.975335685	38	1.346834232	53	0.002807807	-1.285267845	down	0.487295599	-0.876679752	normal	0.296770261	-0.84711469	normal	0.012355336	-1.031048484	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K08671|0|hsa:54760|PCSK4, PC4, SPC5; proprotein convertase subtilisin/kexin type 4; K08671 proprotein convertase subtilisin/kexin type 4 [EC:3.4.21.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family;; Proprotein convertase P-domain	Proprotein convertase subtilisin/kexin type 4 (Precursor) OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proprotein convertase subtilisin/kexin type 4 isoform X2 [Sus scrofa]
ENSG00000115266(APC2)	--	0.469332118	89	1.457853938	139	0.728292753	146	0.299213438	59	0.293943353	56	0.387220352	75	0.780265943	-0.610873843	normal	0.000176944	-1.309783709	down	0.021362954	-0.955238763	normal	0.005798024	-0.997162868	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: beta-catenin binding (GO:0008013);; Molecular Function: microtubule binding (GO:0008017);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K02085|0|hsa:10297|APC2, APCL; adenomatosis polyposis coli 2; K02085 adenomatosis polyposis coli protein (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Basal cell carcinoma (ko05217)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	APC basic domain;; Adenomatous polyposis coli tumour suppressor protein;; APC cysteine-rich region;; Armadillo/beta-catenin-like repeat;; SAMP Motif	Adenomatous polyposis coli protein 2 GN=APC2 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	adenomatous polyposis coli protein 2 [Sus scrofa] 
ENSG00000115267(IFIH1)	--	1.399285	87	1.204762	86	1.708442	81	1.717801	114	1.52493	80	1.477848	105	0.926443913	0.353644803	normal	0.968436752	-0.123510711	normal	0.928565186	0.360182389	normal	0.693810868	0.213595356	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K12647|0|hsa:64135|IFIH1, AGS7, Hlcd, IDDM19, MDA-5, MDA5, RLR-2; interferon induced with helicase C domain 1 (EC:3.6.4.13); K12647 interferon-induced helicase C domain-containing protein 1 [EC:3.6.4.13] (A)"	RIG-I-like receptor signaling pathway (ko04622);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[R]	General function prediction only	"C-terminal domain of RIG-I;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Caspase recruitment domain"	Interferon-induced helicase C domain-containing protein 1 GN=IFIH1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: interferon-induced helicase C domain-containing protein 1 [Galeopterus variegatus]
ENSG00000115268(RPS15)	--	1013.7317	5614	875.741087	5020	911.6268	5338	969.646996	5746	1029.583935	5690	885.56536	5052	0.994074263	0.002695936	normal	0.989260189	0.159269642	normal	0.99249912	-0.087710562	normal	0.936795438	0.024357815	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02958|2.83094e-67|ptr:455550|RPS15; 40S ribosomal protein S15; K02958 small subunit ribosomal protein S15e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S19	40S ribosomal protein S15 GN=RPS15 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S15 [Orcinus orca]
ENSG00000115271(GCA)	--	13.84825969	331	10.81063932	266	11.21990044	269	8.650380001	212	8.798519	213	5.415550138	131	0.084042879	-0.669680177	normal	0.874683319	-0.339835336	normal	0.000217821	-1.037788932	down	0.011070341	-0.661826825	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF-hand domain pair	Grancalcin GN=GCA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: grancalcin isoform X2 [Equus przewalskii]
ENSG00000115274(INO80B)	--	36.64227245	732	32.293539	652	33.06909889	672	22.92132572	459	22.98575573	445	19.46557425	396	0.010969371	-0.70230182	normal	0.168383277	-0.570879965	normal	0.002877025	-0.76897117	normal	6.82E-05	-0.682965125	normal	--	--	Cellular Component: Ino80 complex (GO:0031011);; 	K11666|2.29538e-142|pps:100990570|INO80B; INO80 complex subunit B; K11666 INO80 complex subunit B (A)	--	--	--	PAPA-1-like conserved region;; HIT zinc finger	INO80 complex subunit B GN=INO80B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: INO80 complex subunit B [Eptesicus fuscus]
ENSG00000115275(MOGS)	--	34.62459389	1793	31.85961341	1721	32.616091	1749	29.574257	1516	24.70951961	1291	27.06990708	1414	0.939129686	-0.27268351	normal	0.633003711	-0.435740895	normal	0.903498721	-0.314736347	normal	0.03300713	-0.339767768	normal	--	--	--	K01228|0|ptr:740472|MOGS; mannosyl-oligosaccharide glucosidase; K01228 mannosyl-oligosaccharide glucosidase [EC:3.2.1.106] (A)	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Mannosyl oligosaccharide glucosidase	Mannosyl-oligosaccharide glucosidase GN=MOGS OS=Homo sapiens (Human) PE=1 SV=5	G	Carbohydrate transport and metabolism	PREDICTED: mannosyl-oligosaccharide glucosidase [Sus scrofa]
ENSG00000115282(TTC31)	--	9.54465947	583	9.446780246	595	10.38641986	607	7.054328498	405	6.852188	394	5.9899392	363	0.210757292	-0.554641729	normal	0.092374643	-0.614187772	normal	0.005745804	-0.747582885	normal	0.000390695	-0.640767175	normal	[R]	General function prediction only	--	--	--	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 31 GN=TTC31 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tetratricopeptide repeat protein 31 isoform X1 [Equus przewalskii]
ENSG00000115286(NDUFS7)	--	30.9904756	513	27.55505969	505	32.06599189	586	34.7789163	592	38.0135694	628	34.9123095	594	0.955737616	0.175317013	normal	0.899665613	0.292268434	normal	0.973521953	0.011242008	normal	0.530857893	0.156615554	normal	[C]	Energy production and conversion	Molecular Function: iron-sulfur cluster binding (GO:0051536);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K03940|6.00364e-119|mcf:102119049|NDUFS7; NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase); K03940 NADH dehydrogenase (ubiquinone) Fe-S protein 7 [EC:1.6.5.3 1.6.99.3] (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"NADH ubiquinone oxidoreductase, 20 Kd subunit"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial (Precursor) GN=NDUFS7 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial [Orycteropus afer afer]"
ENSG00000115289(PCGF1)	--	13.91569289	213	15.64528	227	15.65620186	231	8.215745093	131	10.110203	146	10.80985	168	0.107935224	-0.725376633	normal	0.226344891	-0.652682432	normal	0.71727175	-0.464144596	normal	0.028153043	-0.612866895	normal	[T]	Signal transduction mechanisms	Molecular Function: metal ion binding (GO:0046872);; 	K11487|0|pps:100986172|PCGF1; polycomb group ring finger 1; K11487 polycomb group RING finger protein 1 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[S]	Function unknown	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	Polycomb group RING finger protein 1 GN=PCGF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: polycomb group RING finger protein 1 [Oryctolagus cuniculus] 
ENSG00000115290(GRB14)	--	12.38957499	471	11.0595873	444	10.46279028	371	4.079495751	160	6.324563601	229	4.24730384	154	5.78E-13	-1.579201222	down	9.41E-05	-0.971941469	normal	1.01E-07	-1.268493729	down	8.24E-10	-1.265302281	down	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	BPS (Between PH and SH2);; SH2 domain;; Ras association (RalGDS/AF-6) domain;; PH domain	Growth factor receptor-bound protein 14 GN=GRB14 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: growth factor receptor-bound protein 14 isoform X1 [Camelus bactrianus] 
ENSG00000115295(CLIP4)	--	29.49558101	1840	30.3419777	1918	31.43542888	1913	22.16078823	1325	23.16739079	1398	27.23502898	1709	0.318025243	-0.504047173	normal	0.465776726	-0.477222182	normal	0.975324059	-0.170832954	normal	0.014970475	-0.376052386	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	"K10423|0|hsa:79745|CLIP4, RSNL2; CAP-GLY domain containing linker protein family, member 4; K10423 CAP-Gly domain-containing linker protein 3/4 (A)"	--	[ZR]	Cytoskeleton;; General function prediction only	CAP-Gly domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	CAP-Gly domain-containing linker protein 4 GN=CLIP4 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: CAP-Gly domain-containing linker protein 4 isoform X1 [Tupaia chinensis]
ENSG00000115297(TLX2)	--	0.43598222	14	0.419055744	14	0.686336981	24	0.0605971	2	0.119830398	3	0.094098291	3	--	--	--	--	--	--	0.041423597	-2.50591799	normal	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K15606|1.93626e-83|pon:100432081|TLX2; T-cell leukemia homeobox 2; K15606 T-cell leukemia homeobox protein 2 (A)	--	[R]	General function prediction only	Homeobox domain	T-cell leukemia homeobox protein 2 GN=TLX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: T-cell leukemia homeobox protein 2 [Physeter catodon]
ENSG00000115306(SPTBN1)	--	63.78428369	13719	68.55294	15300	68.58128559	15354	91.3702158	20558	87.86023138	19641	94.931504	21409	0.3858497	0.552641461	normal	0.974106645	0.338880543	normal	0.793765185	0.47127193	normal	0.009883551	0.452424864	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K06115|0|ptr:459234|SPTBN1; spectrin, beta, non-erythrocytic 1; K06115 spectrin beta (A)"	--	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Pleckstrin homology domain;; PH domain;; CAMSAP CH domain	"Spectrin beta chain, non-erythrocytic 1 GN=SPTBN1 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: spectrin beta chain, non-erythrocytic 1 isoform X1 [Galeopterus variegatus]"
ENSG00000115307(AUP1)	--	75.8664	1972	92.183	2444	82.4272	2186	65.6629	1711	68.0093	1759	75.2746	1974	0.959627896	-0.235454898	normal	0.40057573	-0.495552147	normal	0.979529031	-0.155349703	normal	0.065801793	-0.299063671	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[I]	Lipid transport and metabolism	CUE domain	Ancient ubiquitous protein 1 GN=AUP1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: ancient ubiquitous protein 1 [Eptesicus fuscus]
ENSG00000115310(RTN4)	--	329.5839973	11771	340.9357083	12421	329.3032911	12018	370.0858649	13230	316.4916892	11307	359.9149232	12967	0.995368318	0.137726946	normal	0.994384716	-0.156971644	normal	0.996112381	0.101344193	normal	0.926651929	0.029313251	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Reticulon	Reticulon-4 GN=RTN4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: reticulon-4 isoform 1 [Ceratotherium simum simum]
ENSG00000115317(HTRA2)	--	9.9214955	402	9.174756	385	11.706644	469	10.97354	424	8.964536274	369	8.94153	358	0.969014308	0.045865808	normal	0.96529116	-0.082333805	normal	0.752769023	-0.396451997	normal	0.611299089	-0.147356181	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; 	"K08669|0|hsa:27429|HTRA2, OMI, PARK13, PRSS25; HtrA serine peptidase 2 (EC:3.4.21.108); K08669 HtrA serine peptidase 2 [EC:3.4.21.108] (A)"	Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Trypsin-like peptidase domain;; Trypsin;; PDZ domain;; PDZ domain (Also known as DHR or GLGF);; Peptidase S46	"Serine protease HTRA2, mitochondrial (Precursor) GN=HTRA2 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: serine protease HTRA2, mitochondrial [Felis catus]"
ENSG00000115318(LOXL3)	--	1.070560719	60	0.496478831	30	0.718626935	47	0.724332659	42	0.889386274	51	0.7158404	38	0.921912659	-0.529120523	normal	0.865278063	0.71613666	normal	0.971702697	-0.304052367	normal	0.932235497	-0.085731905	normal	--	--	"Molecular Function: scavenger receptor activity (GO:0005044);; Molecular Function: copper ion binding (GO:0005507);; Cellular Component: membrane (GO:0016020);; Molecular Function: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (GO:0016641);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00280|0|nle:100590303|LOXL3; lysyl oxidase-like 3; K00280 lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] (A)	--	--	--	Lysyl oxidase;; Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	Lysyl oxidase homolog 3 (Precursor) GN=LOXL3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: lysyl oxidase homolog 3 isoform X2 [Panthera tigris altaica]
ENSG00000115325(DOK1)	--	4.176078	173	3.266319	138	3.654842	165	1.924513	87	2.609202	123	1.895039	81	0.003955395	-1.009613737	down	0.955969916	-0.18528438	normal	0.004521827	-1.021125559	down	0.024007372	-0.730962427	normal	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	"K14752|0|ptr:741064|DOK1; docking protein 1, 62kDa (downstream of tyrosine kinase 1); K14752 docking protein 1 (A)"	Measles (ko05162)	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type)	Docking protein 1 GN=DOK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: docking protein 1 [Galeopterus variegatus]
ENSG00000115339(GALNT3)	--	0.127763011	7	0.099222112	4	0.036578289	1	0.199909298	12	0.502744498	32	0.556192537	23	--	--	--	0.002943381	2.585965468	up	0.004694219	3.280893084	up	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	--	"K00710|0|hsa:2591|GALNT3, GalNAc-T3, HFTC, HHS; polypeptide N-acetylgalactosaminyltransferase 3 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 3 GN=GALNT3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 3 [Ceratotherium simum simum]
ENSG00000115350(POLE4)	--	19.23012	339	25.17104	463	24.67211	439	22.1484	395	17.05637	291	21.95975	391	0.948978759	0.188941262	normal	0.035955077	-0.68855582	normal	0.953379105	-0.17470568	normal	0.469724939	-0.225743413	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K03506|2.64298e-55|ptr:459343|POLE4; polymerase (DNA-directed), epsilon 4, accessory subunit; K03506 DNA polymerase epsilon subunit 4 [EC:2.7.7.7] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; HTLV-I infection (ko05166)	[L]	"Replication, recombination and repair"	Histone-like transcription factor (CBF/NF-Y) and archaeal histone;; Core histone H2A/H2B/H3/H4	DNA polymerase epsilon subunit 4 GN=POLE4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase epsilon subunit 4 [Odobenus rosmarus divergens]
ENSG00000115353(TACR1)	--	0.1092678	3	0.0330802	3	0.0109191	0	0	0	0.0106862	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04222|0|pps:100982037|TACR1; tachykinin receptor 1; K04222 tachykinin receptor 1 (A)	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Measles (ko05162)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family)	Substance-P receptor GN=TACR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	substance-P receptor [Canis lupus familiaris] 
ENSG00000115355(CCDC88A)	--	17.02813771	3060	15.8656036	2708	21.4911555	3131	15.64782341	2738	14.81769169	2570	10.59342045	1954	0.979134917	-0.19113994	normal	0.98674292	-0.09683042	normal	0.006813989	-0.688059802	normal	0.098238996	-0.315230802	normal	--	--	--	--	--	[S]	Function unknown	HOOK protein	Girdin OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: girdin isoform X5 [Equus przewalskii]
ENSG00000115361(ACADL)	--	0.242907991	10	0.071864631	3	0.120282421	4	0.215381676	9	0.210352019	8	0.239558391	10	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00255|0|hsa:33|ACADL, ACAD4, LCAD; acyl-CoA dehydrogenase, long chain (EC:1.3.8.8); K00255 long-chain-acyl-CoA dehydrogenase [EC:1.3.8.8] (A)"	Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320)	[EI]	Amino acid transport and metabolism;; Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	"Long-chain specific acyl-CoA dehydrogenase, mitochondrial (Precursor) GN=ACADL OS=Homo sapiens (Human) PE=2 SV=2"	I	Lipid transport and metabolism	"PREDICTED: long-chain specific acyl-CoA dehydrogenase, mitochondrial [Balaenoptera acutorostrata scammoni]"
ENSG00000115363(EVA1A)	--	7.885734346	223	4.424984142	152	6.912103626	210	10.784907	271	9.647500041	276	9.424664678	213	0.931106414	0.24885963	normal	0.011248382	0.832934866	normal	0.9669344	0.012086238	normal	0.222832775	0.356028269	normal	--	--	--	--	--	--	--	FAM176 family	Protein eva-1 homolog A GN=EVA1A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein eva-1 homolog A [Condylura cristata]
ENSG00000115364(MRPL19)	--	42.52317	2089	40.88167701	2027	45.826095	2114	37.14281311	1720	36.56493325	1706	29.799808	1435	0.914778396	-0.310983641	normal	0.94532347	-0.269935164	normal	0.115846831	-0.566720846	normal	0.013864821	-0.379607123	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02884|0|pps:100979894|MRPL19; mitochondrial ribosomal protein L19; K02884 large subunit ribosomal protein L19 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L19	"39S ribosomal protein L19, mitochondrial (Precursor) GN=MRPL19 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L19, mitochondrial [Ceratotherium simum simum]"
ENSG00000115365(LANCL1)	--	27.26668995	1754	24.36588834	1540	25.42201243	1597	15.09180761	966	16.06837708	1008	13.74570523	851	1.95E-05	-0.890318304	normal	0.035157017	-0.632087916	normal	1.02E-05	-0.915217466	normal	5.42E-09	-0.8134111	normal	[V]	Defense mechanisms	--	--	--	[V]	Defense mechanisms	Lanthionine synthetase C-like protein	LanC-like protein 1 GN=LANCL1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: lanC-like protein 1 [Oryctolagus cuniculus] 
ENSG00000115368(WDR75)	--	24.00920908	1129	25.49810882	1193	24.17960826	1117	18.48147039	726	17.234834	809	13.96297	659	0.015353641	-0.666694808	normal	0.105804228	-0.580908736	normal	0.001284277	-0.768200144	normal	7.47E-06	-0.669891225	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14552|0|hsa:84128|WDR75, NET16, UTP17; WD repeat domain 75; K14552 NET1-associated nuclear protein 1 (U3 small nucleolar RNA-associated protein 17) (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 75 GN=WDR75 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 75 [Equus przewalskii]
ENSG00000115380(EFEMP1)	--	8.8144473	394	7.119158615	323	9.68098226	373	22.38949999	979	25.19965709	1043	18.41813942	803	1.04E-10	1.279012322	up	0	1.665123324	up	1.80E-07	1.094834492	up	1.87E-14	1.35235977	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K18262|0|ptr:455416|EFEMP1; EGF containing fibulin-like extracellular matrix protein 1; K18262 EGF-containing fibulin-like extracellular matrix protein 1 (A)	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Coagulation Factor Xa inhibitory site;; EGF-like domain	EGF-containing fibulin-like extracellular matrix protein 1 (Precursor) GN=EFEMP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: EGF-containing fibulin-like extracellular matrix protein 1 [Oryctolagus cuniculus] 
ENSG00000115392(FANCL)	--	30.42027401	702	27.52115234	642	29.96861128	728	17.066409	411	14.83329532	349	13.44607775	338	0.001172646	-0.800844715	normal	0.000165143	-0.897857831	normal	1.53E-07	-1.111732869	down	2.37E-08	-0.937811427	normal	--	--	--	"K10606|0|hsa:55120|FANCL, FAAP43, PHF9, POG; Fanconi anemia, complementation group L; K10606 E3 ubiquitin-protein ligase FANCL [EC:6.3.2.19] (A)"	Fanconi anemia pathway (ko03460);; Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	WD-repeat region;; FANCL C-terminal domain	E3 ubiquitin-protein ligase FANCL GN=FANCL OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase FANCL isoform 1 [Odobenus rosmarus divergens]
ENSG00000115414(FN1)	--	126.0719298	22456	81.69483504	14377	98.7850678	17909	71.165726	12421	105.895722	18369	60.05320759	10821	2.70E-05	-0.885069201	normal	0.975145119	0.332052898	normal	0.003856436	-0.735061677	normal	0.360398524	-0.416934937	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; 	K05717|0|pps:100992555|FN1; fibronectin 1; K05717 fibronectin 1 (A)	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Small cell lung cancer (ko05222)	--	--	"Fibronectin type III domain;; Fibronectin type I domain;; Fibronectin type II domain;; Interferon-alpha/beta receptor, fibronectin type III;; Uncharacterised conserved protein (DUF2369);; Protein of unknown function (DUF1410)"	Ugl-Y3 (Precursor) GN=FN1 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	hypothetical protein PANDA_001577 [Ailuropoda melanoleuca]
ENSG00000115415(STAT1)	--	82.28639196	5960	77.1214087	5683	72.566135	5242	44.65069298	3328	53.00315339	3803	55.20795904	3991	2.36E-05	-0.871184037	normal	0.090521972	-0.600744503	normal	0.832317333	-0.401525331	normal	1.60E-05	-0.623118838	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K11220|0|pps:100971620|STAT1; signal transducer and activator of transcription 1, 91kDa; K11220 signal transducer and activator of transcription 1 (A)"	Chemokine signaling pathway (ko04062);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Pancreatic cancer (ko05212);; Inflammatory bowel disease (IBD) (ko05321)	[KT]	Transcription;; Signal transduction mechanisms	"STAT protein, DNA binding domain;; STAT protein, all-alpha domain;; STAT protein, protein interaction domain;; STAT1 TAZ2 binding domain;; SH2 domain"	Signal transducer and activator of transcription 1-alpha/beta GN=STAT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: signal transducer and activator of transcription 1-like [Odobenus rosmarus divergens]
ENSG00000115419(GLS)	--	95.89292655	5713	105.1730114	6301	116.5262446	6882	160.8642563	10017	137.6188782	8110	128.3067133	7708	0.000676561	0.779137631	normal	0.946779101	0.342621896	normal	0.991929325	0.155204996	normal	0.019263424	0.42942747	normal	[E]	Amino acid transport and metabolism	Molecular Function: glutaminase activity (GO:0004359);; Molecular Function: protein binding (GO:0005515);; Biological Process: glutamine metabolic process (GO:0006541);; 	K01425|0|ptr:470606|GLS; glutaminase; K01425 glutaminase [EC:3.5.1.2] (A)	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; D-Glutamine and D-glutamate metabolism (ko00471);; Glutamatergic synapse (ko04724);; GABAergic synapse (ko04727);; Proximal tubule bicarbonate reclamation (ko04964);; MicroRNAs in cancer (ko05206);; Central carbon metabolism in cancer (ko05230)"	[E]	Amino acid transport and metabolism	Glutaminase;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	"Glutaminase kidney isoform, mitochondrial (Precursor) GN=GLS OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: glutaminase kidney isoform, mitochondrial isoform X1 [Oryctolagus cuniculus]"
ENSG00000115421(PAPOLG)	--	5.636068675	441	5.663301024	442	6.107108142	451	4.500610433	363	4.628175641	356	4.262825798	334	0.88332692	-0.310446958	normal	0.861487497	-0.332325957	normal	0.64620183	-0.439850264	normal	0.105576068	-0.362641873	normal	[A]	RNA processing and modification	Molecular Function: RNA binding (GO:0003723);; Molecular Function: polynucleotide adenylyltransferase activity (GO:0004652);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; Biological Process: RNA polyadenylation (GO:0043631);; 	K14376|0|pps:100967304|PAPOLG; poly(A) polymerase gamma; K14376 poly(A) polymerase [EC:2.7.7.19] (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Poly(A) polymerase central domain;; Poly(A) polymerase predicted RNA binding domain;; Nucleotidyltransferase domain	Poly(A) polymerase gamma GN=PAPOLG OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: poly(A) polymerase gamma [Tupaia chinensis]
ENSG00000115423(DNAH6)	--	0.044720422	11	0.040305227	10	0.028202058	6	0.004045891	1	0.007887872	1	0.012131516	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:1768|DNAH6, DNHL1, Dnahc6, HL-2, HL2; dynein, axonemal, heavy chain 6; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D4;; P-loop containing dynein motor region D3;; ATP-binding dynein motor region D5;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA domain;; AAA ATPase domain;; AAA domain;; RNA helicase;; Type II/IV secretion system protein;; Sigma-54 interaction domain"	"Dynein heavy chain 6, axonemal GN=DNAH6 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 6, axonemal [Ceratotherium simum simum]"
ENSG00000115425(PECR)	--	16.96111109	512	16.218494	503	18.08425002	525	13.81334636	460	12.923844	395	14.650774	453	0.95197643	-0.184756903	normal	0.805822645	-0.368877416	normal	0.940688055	-0.220413643	normal	0.261049634	-0.256806953	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K07753|0|hsa:55825|PECR, DCRRP, HPDHASE, HSA250303, PVIARL, SDR29C1, TERP; peroxisomal trans-2-enoyl-CoA reductase (EC:1.3.1.38); K07753 peroxisomal trans-2-enoyl-CoA reductase [EC:1.3.1.38] (A)"	Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; Peroxisome (ko04146)	[R]	General function prediction only	Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase;; KR domain;; NADP oxidoreductase coenzyme F420-dependent	Peroxisomal trans-2-enoyl-CoA reductase GN=PECR OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: peroxisomal trans-2-enoyl-CoA reductase-like isoform X2 [Mustela putorius furo]
ENSG00000115446(UNC50)	--	38.75726864	590	45.890711	701	35.47642008	537	24.04253	370	23.68303068	358	27.47587027	418	0.015671022	-0.701691744	normal	1.09E-05	-0.987840806	normal	0.801143579	-0.36853105	normal	0.000116643	-0.694863452	normal	--	--	--	--	--	[S]	Function unknown	UNC-50 family	Protein unc-50 homolog GN=UNC50 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	hypothetical protein PANDA_008691 [Ailuropoda melanoleuca]
ENSG00000115457(IGFBP2)	--	65.11710102	1562	51.97401793	1302	50.40611388	1282	20.06506906	490	23.09663089	556	18.34790776	448	0	-1.700211412	down	1.62E-10	-1.24671374	down	5.55E-16	-1.521937258	down	1.80E-20	-1.494050041	down	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Thyroglobulin type-1 repeat;; Insulin-like growth factor binding protein	Insulin-like growth factor-binding protein 2 (Precursor) GN=IGFBP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: insulin-like growth factor-binding protein 2, partial [Tupaia chinensis]"
ENSG00000115459(ELMOD3)	--	6.592627752	301	8.151877732	394	8.317376	397	5.713335104	289	6.0961209	289	7.051307219	352	0.964205683	-0.089062242	normal	0.596168658	-0.466453155	normal	0.951239658	-0.181121821	normal	0.344674956	-0.252094772	normal	--	--	--	--	--	[S]	Function unknown	ELMO/CED-12 family	ELMO domain-containing protein 3 GN=ELMOD3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ELMO domain-containing protein 3 isoform X1 [Equus przewalskii] 
ENSG00000115461(IGFBP5)	--	0.015956566	2	0.015820136	2	0.348376547	4	0.104332206	13	0.248755445	31	0.039537667	5	--	--	--	0.000293255	3.194193045	up	--	--	--	--	--	--	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Thyroglobulin type-1 repeat;; Insulin-like growth factor binding protein	Insulin-like growth factor-binding protein 5 (Precursor) GN=IGFBP5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: insulin-like growth factor binding protein-5 [Equus caballus] 
ENSG00000115464(USP34)	--	31.4520698	5537	36.90046405	5544	28.94257881	5104	21.39534436	3825	23.64296	4140	26.42327356	4232	0.162085529	-0.564287448	normal	0.732693094	-0.442582796	normal	0.965975532	-0.278489385	normal	0.005400313	-0.429141158	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11853|0|hsa:9736|USP34; ubiquitin specific peptidase 34 (EC:3.4.19.12); K11853 ubiquitin carboxyl-terminal hydrolase 34 [EC:3.4.19.12] (A)	--	--	--	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 34 GN=USP34 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 34 [Odobenus rosmarus divergens]
ENSG00000115468(EFHD1)	--	3.157152414	117	2.243154791	69	1.444027277	50	0.350114705	13	1.306439303	48	0.838918398	23	5.22E-15	-3.05658522	down	0.898804182	-0.53095765	normal	0.459473634	-1.07932543	normal	0.074854729	-1.510736504	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[R]	General function prediction only	EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand	EF-hand domain-containing protein D1 GN=EFHD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: EF-hand domain-containing protein D1 [Lipotes vexillifer]
ENSG00000115474(KCNJ13)	--	0.130834	6	0.2069953	8	0.303479	7	0	0	0.1629031	1	0.118045	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05006|0|ptr:100615579|KCNJ13; potassium inwardly-rectifying channel, subfamily J, member 13; K05006 potassium inwardly-rectifying channel subfamily J member 13 (A)"	Protein digestion and absorption (ko04974)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	Inward rectifier potassium channel 13 GN=KCNJ13 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: inward rectifier potassium channel 13 isoform X1 [Vicugna pacos] 
ENSG00000115484(CCT4)	--	141.54464	5775	140.858715	5812	158.1249205	6443	158.434211	6528	143.90285	5848	120.226927	4903	0.991321196	0.145951311	normal	0.993959359	-0.012514703	normal	0.849514207	-0.402250693	normal	0.735547601	-0.083222987	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09496|0|pps:100971788|CCT4; chaperonin containing TCP1, subunit 4 (delta); K09496 T-complex protein 1 subunit delta (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit delta GN=CCT4 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: T-complex protein 1 subunit delta [Felis catus] 
ENSG00000115486(GGCX)	--	14.894448	1797	13.626285	1532	15.105929	1594	12.8752138	1519	13.1203176	1502	13.34847273	1401	0.938973864	-0.27304651	normal	0.983015166	-0.049908285	normal	0.96750048	-0.194289351	normal	0.358125618	-0.176296718	normal	--	--	Molecular Function: gamma-glutamyl carboxylase activity (GO:0008488);; Biological Process: peptidyl-glutamic acid carboxylation (GO:0017187);; 	"K10106|0|hsa:2677|GGCX, VKCFD1; gamma-glutamyl carboxylase (EC:4.1.1.90); K10106 vitamin K-dependent gamma-carboxylase [EC:4.1.1.90] (A)"	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130)	--	--	Vitamin K-dependent gamma-carboxylase	Vitamin K-dependent gamma-carboxylase GN=GGCX OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: vitamin K-dependent gamma-carboxylase isoform X1 [Galeopterus variegatus]
ENSG00000115504(EHBP1)	--	39.6867949	3395	31.76253087	2987	39.4768749	3344	27.06879119	2433	33.03893977	2914	28.17466173	2549	0.328832101	-0.511232792	normal	0.98914994	-0.057093651	normal	0.794751334	-0.399727202	normal	0.044605764	-0.321583658	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Protein of unknown function (DUF3585);; N-terminal C2 in EEIG1 and EHBP1 proteins;; Calponin homology (CH) domain;; CAMSAP CH domain	EH domain-binding protein 1 GN=EHBP1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: EH domain-binding protein 1 isoform X5 [Panthera tigris altaica]
ENSG00000115507(OTX1)	--	3.161483001	156	3.225867376	154	3.080367016	148	1.261665559	63	2.040636171	95	1.166489594	58	5.18E-05	-1.317814091	down	0.278207357	-0.709398541	normal	6.48E-05	-1.337148726	down	0.000511444	-1.105553868	down	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: multicellular organismal development (GO:0007275);; 	K09326|4.22886e-77|chx:102172273|OTX1; orthodenticle homeobox 1; K09326 homeobox protein OTX1 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[K]	Transcription	Otx1 transcription factor;; Homeobox domain	Homeobox protein OTX1 GN=OTX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: homeobox protein OTX1-like, partial [Capra hircus]"
ENSG00000115514(TXNDC9)	--	23.077552	865	24.521324	877	25.54003423	924	18.2565673	645	15.7545735	594	16.07557279	586	0.533658979	-0.453297007	normal	0.116954922	-0.582312097	normal	0.019878992	-0.663907115	normal	0.000441527	-0.568174952	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Thioredoxin	Thioredoxin domain-containing protein 9 GN=TXNDC9 OS=Homo sapiens (Human) PE=1 SV=2	CO	"Energy production and conversion;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin domain-containing protein 9 [Galeopterus variegatus] 
ENSG00000115520(COQ10B)	--	19.0141013	593	19.23868878	614	16.57242772	528	12.1070453	388	12.1479326	388	12.6331857	403	0.051491129	-0.640738513	normal	0.025993389	-0.681477457	normal	0.743615198	-0.396744738	normal	0.00174885	-0.578690623	normal	[I]	Lipid transport and metabolism	--	K18588|3.53632e-177|nle:100607384|COQ10B; coenzyme Q10 homolog B (S. cerevisiae); K18588 coenzyme Q-binding protein COQ10 (A)	--	[I]	Lipid transport and metabolism	Polyketide cyclase / dehydrase and lipid transport	"Coenzyme Q-binding protein COQ10 homolog B, mitochondrial (Precursor) GN=COQ10B OS=Homo sapiens (Human) PE=2 SV=1"	I	Lipid transport and metabolism	"PREDICTED: coenzyme Q-binding protein COQ10 homolog B, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000115524(SF3B1)	--	77.75539128	6784	69.6050763	6851	70.60792327	6565	57.93844591	5215	55.66230778	5529	53.44976252	5139	0.836988139	-0.410194868	normal	0.949272893	-0.330641151	normal	0.917035048	-0.361504433	normal	0.024676028	-0.368136395	normal	[A]	RNA processing and modification	--	"K12828|0|pale:102890521|SF3B1; splicing factor 3b, subunit 1, 155kDa; K12828 splicing factor 3B subunit 1 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Splicing factor 3B subunit 1;; HEAT repeats;; HEAT repeat;; HEAT-like repeat;; Vacuolar 14 Fab1-binding region	Splicing factor 3B subunit 1 GN=SF3B1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: splicing factor 3B subunit 1 isoform X1 [Pteropus alecto] 
ENSG00000115525(ST3GAL5)	--	31.36657359	1375	19.39653328	876	27.26260399	1145	21.30480066	935	25.12102616	1058	24.82523082	1047	0.079602883	-0.586425513	normal	0.937761076	0.250516282	normal	0.972777996	-0.137188043	normal	0.614034174	-0.180455775	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03370|0|mcf:102139258|ST3GAL5; ST3 beta-galactoside alpha-2,3-sialyltransferase 5; K03370 lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9) [EC:2.4.99.9] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Lactosylceramide alpha-2,3-sialyltransferase GN=ST3GAL5 OS=Homo sapiens (Human) PE=1 SV=4"	G	Carbohydrate transport and metabolism	"PREDICTED: lactosylceramide alpha-2,3-sialyltransferase [Galeopterus variegatus]"
ENSG00000115526(CHST10)	--	9.610920127	563	8.190305012	452	8.08537004	463	5.383802377	312	5.120903792	294	5.095830534	295	0.000298516	-0.879148265	normal	0.086386119	-0.639259526	normal	0.058161054	-0.655881668	normal	0.000123675	-0.73553489	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09674|0|hsa:9486|CHST10, HNK-1ST, HNK1ST; carbohydrate sulfotransferase 10; K09674 carbohydrate 3-sulfotransferase 10 [EC:2.8.2.-] (A)"	Other types of O-glycan biosynthesis (ko00514)	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Sulfotransferase family	Carbohydrate sulfotransferase 10 GN=CHST10 OS=Homo sapiens (Human) PE=1 SV=1	MW	Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: carbohydrate sulfotransferase 10 [Orycteropus afer afer]
ENSG00000115539(PDCL3)	--	19.293904	522	24.43407005	667	25.131452	657	13.44677711	384	13.37146001	361	14.45095227	399	0.514998863	-0.472148278	normal	0.00012527	-0.904281808	normal	0.008043927	-0.725630122	normal	5.82E-05	-0.711287368	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Phosducin	Phosducin-like protein 3 GN=PDCL3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosducin-like protein 3 [Tupaia chinensis]
ENSG00000115540(MOB4)	--	306.8822146	3911	364.888452	4844	375.6581632	4888	282.50603	3564	231.553	2923	223.4661765	2878	0.985629049	-0.164804606	normal	0.001702579	-0.749870825	normal	0.000629259	-0.772154072	normal	0.000874648	-0.564555901	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mob1/phocein family	MOB-like protein phocein GN=MOB4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MOB-like protein phocein isoform X1 [Galeopterus variegatus]
ENSG00000115548(KDM3A)	--	14.9513245	1313	19.7664864	1844	14.88156453	1453	11.02265465	962	9.067269236	837	15.0298274	1316	0.418748992	-0.478932649	normal	1.81E-09	-1.159515968	down	0.974288185	-0.15100144	normal	0.069949109	-0.586041136	normal	--	--	--	"K15601|0|hsa:55818|KDM3A, JHDM2A, JHMD2A, JMJD1, JMJD1A, TSGA; lysine (K)-specific demethylase 3A; K15601 lysine-specific demethylase 3 [EC:1.14.11.-] (A)"	--	[K]	Transcription	"JmjC domain, hydroxylase"	Lysine-specific demethylase 3A GN=KDM3A OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: lysine-specific demethylase 3A [Equus przewalskii]
ENSG00000115556(PLCD4)	--	1.327426	89	1.39845	95	1.179880229	80	0.402092	27	0.787287	52	0.457223	31	5.32E-05	-1.695432683	down	0.253494623	-0.871798352	normal	0.008344874	-1.334054162	down	0.001655701	-1.283831921	down	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05857|0|mcf:102122144|PLCD4; phospholipase C, delta 4; K05857 phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070);; Thyroid hormone signaling pathway (ko04919)	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; EF hand;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; PH domain;; Glycerophosphoryl diester phosphodiesterase family"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 GN=PLCD4 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 isoform X2 [Felis catus]"
ENSG00000115561(CHMP3)	--	82.56578879	4168	94.23504722	4735	82.88746474	4106	75.66745479	3788	74.38335699	3635	84.56860884	4313	0.985917018	-0.168685948	normal	0.830594745	-0.402688358	normal	0.991819846	0.062644133	normal	0.386034987	-0.169566728	normal	[N]	Cell motility	Biological Process: vacuolar transport (GO:0007034);; 	K12193|3.88677e-124|pps:100970314|CHMP3; charged multivesicular body protein 3; K12193 charged multivesicular body protein 3 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snf7	Charged multivesicular body protein 3 GN=CHMP3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 3-like [Myotis lucifugus]
ENSG00000115568(ZNF142)	--	5.520759658	883	5.867205892	922	8.543575943	1008	4.4921089	634	4.396295607	659	5.04408419	740	0.315990934	-0.507714922	normal	0.345583757	-0.504930241	normal	0.530629474	-0.453392742	normal	0.002642416	-0.489033962	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; C2H2-type zinc-finger domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 142 GN=ZNF142 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: zinc finger protein 142 isoform 2 [Equus caballus]
ENSG00000115590(IL1R2)	--	0.087190015	2	0	0	0	0	0.302029258	7	0.200967339	4	0.344715127	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04387|0|ptr:470455|IL1R2; interleukin 1 receptor, type II; K04387 interleukin 1 receptor type II (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; Hematopoietic cell lineage (ko04640);; Amoebiasis (ko05146);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	"Interleukin-1 receptor type 2, soluble form (Precursor) GN=IL1R2 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor type 2 isoform X2 [Ursus maritimus]
ENSG00000115594(IL1R1)	--	8.945440272	752	7.787627556	730	7.810603314	668	7.813120172	743	10.19640711	902	7.294570978	654	0.97519591	-0.048103837	normal	0.912858018	0.283275644	normal	0.974203455	-0.038760223	normal	0.802255264	0.075086686	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K04386|0|hsa:3554|IL1R1, CD121A, D2S1473, IL-1R-alpha, IL1R, IL1RA, P80; interleukin 1 receptor, type I; K04386 interleukin 1 receptor type I (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Hematopoietic cell lineage (ko04640);; Inflammatory mediator regulation of TRP channels (ko04750);; Amoebiasis (ko05146);; HTLV-I infection (ko05166)	--	--	TIR domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	"Interleukin-1 receptor type 1, soluble form (Precursor) GN=IL1R1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor type 1 [Felis catus] 
ENSG00000115596(WNT6)	--	0	0	0	0	0.124588	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00445|0|hsa:7475|WNT6; wingless-type MMTV integration site family, member 6; K00445 wingless-type MMTV integration site family, member 6 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-6 (Precursor) GN=WNT6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-6 [Condylura cristata]
ENSG00000115602(IL1RL1)	--	0.219252669	15	0.1865529	12	0.309590165	10	0.369290456	20	0.213783691	14	0.319393459	19	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K05171|0|ptr:740174|IL1RL1; interleukin-1 receptor-like 1; K05171 interleukin 1 receptor-like 1 (A)	--	--	--	TIR domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Interleukin-1 receptor-like 1 (Precursor) GN=IL1RL1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: interleukin 1 receptor-like 1 [Equus caballus] 
ENSG00000115616(SLC9A2)	--	3.002987	295	2.841604685	283	3.068845824	302	1.199747786	119	1.055324564	105	1.259399777	127	1.32E-07	-1.329295656	down	1.83E-08	-1.438688579	down	8.95E-07	-1.248070611	down	1.13E-08	-1.346996811	down	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14722|0|hsa:6549|SLC9A2, NHE2; solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2; K14722 solute carrier family 9 (sodium/hydrogen exchanger), member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 2 GN=SLC9A2 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 2 [Mustela putorius furo] 
ENSG00000115641(FHL2)	--	37.91070124	993	26.36389569	684	40.62948039	1074	52.22267299	1360	43.76886414	1113	33.70859652	882	0.651983507	0.42234839	normal	0.014453572	0.679769702	normal	0.909085868	-0.291980419	normal	0.536190056	0.264392327	normal	--	--	--	K14380|0|pon:100451668|FHL2; four and a half LIM domains 2; K14380 four and a half LIM domains protein 2 (A)	Osteoclast differentiation (ko04380)	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	LIM domain	Four and a half LIM domains protein 2 GN=FHL2 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: four and a half LIM domains protein 2 [Oryctolagus cuniculus] 
ENSG00000115648(MLPH)	--	56.32803474	3236	63.44652864	3526	65.17380806	3745	45.91112429	2495	45.80712865	2602	61.18239228	3361	0.774840137	-0.405783921	normal	0.606118721	-0.459607634	normal	0.985099551	-0.164296548	normal	0.081696973	-0.333097549	normal	--	--	--	--	--	--	--	FYVE-type zinc finger;; Rab effector MyRIP/melanophilin C-terminus	Melanophilin GN=MLPH OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: melanophilin [Ceratotherium simum simum]
ENSG00000115649(CNPPD1)	--	20.23422276	684	20.10380476	705	17.96145769	623	17.0402094	570	15.487039	520	14.38285832	491	0.898712647	-0.293144125	normal	0.541209368	-0.459385966	normal	0.828101682	-0.350838912	normal	0.052012958	-0.369642887	normal	--	--	Biological Process: regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079);; Molecular Function: protein kinase binding (GO:0019901);; 	--	--	[R]	General function prediction only	Cyclin	Protein CNPPD1 GN=CNPPD1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: protein CNPPD1 [Oryctolagus cuniculus]
ENSG00000115652(UXS1)	--	36.44218764	1439	34.76060643	1362	36.6155	1443	25.17274964	990	24.52768125	966	23.60774796	931	0.109167051	-0.569660372	normal	0.289219881	-0.516373742	normal	0.025479637	-0.639668213	normal	8.52E-05	-0.577157427	normal	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: UDP-glucuronate decarboxylase activity (GO:0048040);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K08678|0|hsa:80146|UXS1, SDR6E1, UGD; UDP-glucuronate decarboxylase 1 (EC:4.1.1.35); K08678 UDP-glucuronate decarboxylase [EC:4.1.1.35] (A)"	Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520)	[GM]	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis	NAD dependent epimerase/dehydratase family;; UDP-glucuronate decarboxylase N-terminal;; RmlD substrate binding domain;; Male sterility protein;; Polysaccharide biosynthesis protein;; 3-beta hydroxysteroid dehydrogenase/isomerase family	UDP-glucuronic acid decarboxylase 1 GN=UXS1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronic acid decarboxylase 1 isoform X1 [Loxodonta africana]
ENSG00000115657(ABCB6)	--	13.21271	682	12.790703	683	12.65983	656	7.809796	403	9.265723	477	10.757069	559	0.001728038	-0.787487592	normal	0.256856524	-0.537889497	normal	0.935151458	-0.238542577	normal	0.004159054	-0.51026876	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05661|0|hsa:10058|ABCB6, ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat; ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group); K05661 ATP-binding cassette, subfamily B (MDR/TAP), member 6 (A)"	ABC transporters (ko02010)	[P]	Inorganic ion transport and metabolism	ABC transporter;; ABC transporter transmembrane region;; AAA domain	"ATP-binding cassette sub-family B member 6, mitochondrial GN=ABCB6 OS=Homo sapiens (Human) PE=1 SV=1"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: ATP-binding cassette sub-family B member 6, mitochondrial [Myotis brandtii] "
ENSG00000115661(STK16)	--	14.187843	461	11.341358	360	14.56475071	449	12.1824134	351	10.667922	316	11.594814	350	0.689167571	-0.422508471	normal	0.942320209	-0.208562975	normal	0.813009492	-0.366251023	normal	0.139971855	-0.341540205	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08856|0|pon:100449938|STK16; serine/threonine kinase 16; K08856 serine/threonine kinase 16 [EC:2.7.11.1] (A)	--	[KIT]	Transcription;; Lipid transport and metabolism;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 16 GN=STK16 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 16 isoform X1 [Equus przewalskii] 
ENSG00000115677(HDLBP)	--	165.4192919	15630	162.1768806	15434	157.8426806	15371	108.3673004	10600	112.1492735	11095	110.2180303	11235	0.166699641	-0.591014737	normal	0.66282418	-0.497571115	normal	0.786820128	-0.460449131	normal	0.001756521	-0.51682585	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	--	--	[I]	Lipid transport and metabolism	KH domain;; KH domain;; Mitochondrial inner-membrane-bound regulator;; KH domain;; BMC domain;; NusA-like KH domain;; Uncharacterized protein conserved in archaea (DUF2096)	Vigilin GN=HDLBP OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: vigilin [Galeopterus variegatus] 
ENSG00000115685(PPP1R7)	--	33.31643	822	32.150191	800	38.64450364	900	25.19712711	649	21.83455657	547	23.70165974	591	0.787981356	-0.370969691	normal	0.15366908	-0.568577504	normal	0.057675525	-0.613775988	normal	0.001846226	-0.518376796	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K17550|0|pps:100989214|PPP1R7; protein phosphatase 1, regulatory subunit 7; K17550 protein phosphatase 1 regulatory subunit 7 (A)"	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat	Protein phosphatase 1 regulatory subunit 7 GN=PPP1R7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 7 isoform 1 [Odobenus rosmarus divergens]
ENSG00000115687(PASK)	--	6.056316	634	5.53451275	611	7.06221158	683	3.63976551	385	4.252647267	403	3.297071208	373	0.005027309	-0.748104081	normal	0.081570652	-0.619915312	normal	0.000181728	-0.878328927	normal	1.45E-05	-0.752809535	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: protein phosphorylation (GO:0006468);; "	"K08801|0|hsa:23178|PASK, PASKIN, STK37; PAS domain containing serine/threonine kinase (EC:2.7.11.1); K08801 PAS domain containing serine/threonine kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PAS domain;; PAS fold	PAS domain-containing serine/threonine-protein kinase GN=PASK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: PAS domain-containing serine/threonine-protein kinase [Galeopterus variegatus]
ENSG00000115694(STK25)	--	44.1589886	1729	39.91815488	1567	46.66333062	1757	29.23189515	1072	32.09093211	1137	28.22655829	1084	0.003140836	-0.719644651	normal	0.427018754	-0.483648967	normal	0.004807331	-0.70426146	normal	7.20E-06	-0.638726076	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08838|0|pps:100988003|STK25; serine/threonine kinase 25; K08838 serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 25 GN=STK25 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 25 isoform X1 [Equus caballus]
ENSG00000115705(TPO)	--	0	0	0	0	0.01920494	1	0.009847675	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K00431|0|hsa:7173|TPO, MSA, TDH2A, TPX; thyroid peroxidase (EC:1.11.1.8); K00431 thyroid peroxidase [EC:1.11.1.8] (A)"	Tyrosine metabolism (ko00350);; Thyroid hormone synthesis (ko04918);; Autoimmune thyroid disease (ko05320)	[R]	General function prediction only	Animal haem peroxidase;; Calcium-binding EGF domain;; EGF-like domain	Thyroid peroxidase (Precursor) GN=TPO OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: thyroid peroxidase isoform X1 [Orycteropus afer afer]
ENSG00000115718(PROC)	--	0.866125678	15	0.635527127	19	0.498980847	12	0.843633537	25	2.247631806	52	1.430102157	21	0.971529474	0.653817917	normal	0.095873262	1.363047916	normal	0.973152182	0.728891766	normal	0.238320253	1.069392826	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	K01344|0|ptr:459593|PROC; protein C (inactivator of coagulation factors Va and VIIIa); K01344 protein C (activated) [EC:3.4.21.69] (A)	Complement and coagulation cascades (ko04610)	--	--	Trypsin;; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain;; Coagulation Factor Xa inhibitory site;; Human growth factor-like EGF	Activation peptide (Precursor) GN=PROC OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: vitamin K-dependent protein C isoform X1 [Tupaia chinensis]
ENSG00000115738(ID2)	--	24.852794	520	19.440949	396	20.837834	393	13.0899114	254	14.1249627	270	12.424371	249	3.39E-06	-1.059933067	down	0.256284719	-0.571308093	normal	0.068307423	-0.663439388	normal	0.000189864	-0.78133984	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K17693|1.51231e-92|ptr:749980|ID2; inhibitor of DNA binding 2, dominant negative helix-loop-helix protein; K17693 DNA-binding protein inhibitor ID2 (A)"	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Transcriptional misregulation in cancer (ko05202)	--	--	Helix-loop-helix DNA-binding domain	DNA-binding protein inhibitor ID-2 GN=ID2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-binding protein inhibitor ID-2 isoform X1 [Equus caballus] 
ENSG00000115750(TAF1B)	--	16.93855	725	13.83660128	605	17.45673613	687	9.809231008	443	11.27430122	503	9.463082	400	0.004795542	-0.739479805	normal	0.903739136	-0.287015198	normal	0.001822326	-0.786304982	normal	0.000523696	-0.604823667	normal	--	--	--	"K15213|0|hsa:9014|TAF1B, MGC:9349, RAF1B, RAFI63, SL1, TAFI63; TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa; K15213 TATA box-binding protein-associated factor RNA polymerase I subunit B (A)"	--	--	--	RNA polymerase I-specific transcription initiation factor Rrn7	TATA box-binding protein-associated factor RNA polymerase I subunit B GN=TAF1B OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TATA box-binding protein-associated factor RNA polymerase I subunit B [Orycteropus afer afer]
ENSG00000115756(HPCAL1)	--	121.5446322	3299	87.27580669	2330	111.4602965	3187	56.2731043	1552	50.37022717	1451	32.86987619	1027	1.85E-09	-1.117954266	down	0.005686415	-0.704124119	normal	0	-1.64060779	down	1.61E-05	-1.151367636	down	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region;; Cytoskeletal-regulatory complex EF hand	Hippocalcin-like protein 1 GN=HPCAL1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	hippocalcin-like protein 1 [Bos taurus] 
ENSG00000115758(ODC1)	--	71.90968375	3014	67.99738008	2937	71.56918978	3051	93.32628522	3986	64.53309238	2667	71.20971866	2946	0.868624852	0.37226456	normal	0.982547269	-0.16046525	normal	0.989515298	-0.058786536	normal	0.852200948	0.070386534	normal	[E]	Amino acid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; 	K01581|0|nle:100581966|ODC1; ornithine decarboxylase 1; K01581 ornithine decarboxylase [EC:4.1.1.17] (A)	Arginine and proline metabolism (ko00330);; Glutathione metabolism (ko00480)	[E]	Amino acid transport and metabolism	"Pyridoxal-dependent decarboxylase, pyridoxal binding domain;; Pyridoxal-dependent decarboxylase, C-terminal sheet domain"	Ornithine decarboxylase GN=ODC1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: ornithine decarboxylase [Trichechus manatus latirostris]
ENSG00000115760(BIRC6)	--	11.96973339	3489	12.97137417	3768	12.73763997	3658	13.41055279	3904	14.319415	4153	12.89371078	3768	0.988151286	0.131252534	normal	0.98919957	0.118882889	normal	0.991481528	0.034438419	normal	0.680747049	0.094276499	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Biological Process: apoptotic process (GO:0006915);; Biological Process: regulation of cytokinesis (GO:0032465);; 	"K10586|0|hsa:57448|BIRC6, APOLLON, BRUCE; baculoviral IAP repeat containing 6; K10586 baculoviral IAP repeat-containing protein 6 (apollon) [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Protein of unknown function (DUF3643);; Ubiquitin-conjugating enzyme;; Inhibitor of Apoptosis domain;; UEV domain	Baculoviral IAP repeat-containing protein 6 GN=BIRC6 OS=Homo sapiens (Human) PE=1 SV=2	DO	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: baculoviral IAP repeat-containing protein 6 [Vicugna pacos]
ENSG00000115761(NOL10)	--	22.95894704	1315	21.15053972	1227	21.23008191	1273	18.22903074	1070	19.90582537	1121	15.92618343	954	0.875848086	-0.327858699	normal	0.971315709	-0.151579987	normal	0.645430445	-0.423878913	normal	0.077184764	-0.30007665	normal	[R]	General function prediction only	Cellular Component: nucleus (GO:0005634);; 	K14788|0|pps:100994216|NOL10; nucleolar protein 10; K14788 ribosome biogenesis protein ENP2 (A)	--	[R]	General function prediction only	NUC153 domain	Nucleolar protein 10 GN=NOL10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nucleolar protein 10 isoformX1 [Equus caballus]
ENSG00000115762(PLEKHB2)	--	38.41746013	2610	42.38713479	2772	41.42548801	2797	37.0734522	2414	33.59262256	2103	33.75260748	2238	0.983220995	-0.143368604	normal	0.731264951	-0.419641202	normal	0.908377936	-0.329761903	normal	0.068339727	-0.297384306	normal	--	--	--	--	--	--	--	PH domain	Pleckstrin homology domain-containing family B member 2 GN=PLEKHB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family B member 2 [Galeopterus variegatus] 
ENSG00000115806(GORASP2)	--	41.5284029	1863	44.7818	1957	43.1855889	1843	35.485923	1569	44.195699	1905	32.78421	1473	0.936721598	-0.278364049	normal	0.985221503	-0.060232138	normal	0.886102436	-0.331285346	normal	0.225907284	-0.216333155	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	GRASP55/65 PDZ-like domain;; PDZ domain	Golgi reassembly-stacking protein 2 GN=GORASP2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi reassembly-stacking protein 2 [Oryctolagus cuniculus]
ENSG00000115808(STRN)	--	10.81678992	1508	11.77077258	1632	11.57327859	1550	8.239269323	1221	8.21651187	1191	7.924620199	1107	0.871521154	-0.335025305	normal	0.464888768	-0.475376228	normal	0.360915094	-0.493332106	normal	0.004150524	-0.435932048	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17608|0|hsa:6801|STRN, SG2NA; striatin, calmodulin binding protein; K17608 striatin 1/3/4 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Striatin family;; WD domain, G-beta repeat;; Nucleoporin Nup120/160"	Striatin GN=STRN OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: striatin [Odobenus rosmarus divergens]
ENSG00000115816(CEBPZ)	--	29.8145	2081	31.0807	2167	33.072	2269	26.3424	1848	24.2383	1682	21.5914	1501	0.970635015	-0.201986095	normal	0.802293795	-0.38664083	normal	0.053542054	-0.603925563	normal	0.009504033	-0.395066378	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K14832|0|hsa:10153|CEBPZ, CBF, CBF2, HSP-CBF, NOC1; CCAAT/enhancer binding protein (C/EBP), zeta; K14832 ribosome biogenesis protein MAK21 (A)"	--	[JK]	"Translation, ribosomal structure and biogenesis;; Transcription"	CBF/Mak21 family	CCAAT/enhancer-binding protein zeta GN=CEBPZ OS=Homo sapiens (Human) PE=1 SV=3	JK	"Translation, ribosomal structure and biogenesis;; Transcription"	PREDICTED: CCAAT/enhancer-binding protein zeta [Ceratotherium simum simum]
ENSG00000115825(PRKD3)	--	12.0444399	1146	14.20431221	1181	14.625	1298	12.10371231	1195	11.53417821	1158	10.31332814	1003	0.981043203	0.029532537	normal	0.98004693	-0.049735951	normal	0.779495903	-0.379755439	normal	0.539188707	-0.132727978	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; Biological Process: intracellular signal transduction (GO:0035556);; "	K06070|0|ptr:459158|PRKD3; protein kinase D3; K06070 protein kinase D [EC:2.7.11.13] (A)	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; PH domain;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase D3 GN=PRKD3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase D3 [Balaenoptera acutorostrata scammoni]
ENSG00000115827(DCAF17)	--	6.278533701	535	7.221908132	570	7.221512	572	4.565642911	383	4.381289801	368	4.048768801	348	0.368132995	-0.511282319	normal	0.051709406	-0.650516539	normal	0.011035422	-0.722743791	normal	0.00065221	-0.631115145	normal	--	--	Biological Process: protein ubiquitination (GO:0016567);; 	--	--	--	--	--	DDB1- and CUL4-associated factor 17 GN=DCAF17 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DDB1- and CUL4-associated factor 17 isoform X1 [Galeopterus variegatus]
ENSG00000115828(QPCT)	--	41.476505	1155	38.99405062	1097	36.203308	1011	39.403502	1105	42.211512	1176	38.894615	1087	0.977567859	-0.094550137	normal	0.978302875	0.078793057	normal	0.97655153	0.096138787	normal	0.93870179	0.024317043	normal	--	--	--	K00683|0|pps:100979371|QPCT; glutaminyl-peptide cyclotransferase; K00683 glutaminyl-peptide cyclotransferase [EC:2.3.2.5] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M28	Glutaminyl-peptide cyclotransferase (Precursor) GN=QPCT OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: glutaminyl-peptide cyclotransferase [Ceratotherium simum simum]
ENSG00000115839(RAB3GAP1)	--	18.046529	1497	18.10545011	1465	17.0896321	1440	12.90884057	1095	14.07376011	1182	13.2590396	1144	0.409957384	-0.481395253	normal	0.880149269	-0.330716295	normal	0.862544946	-0.33987182	normal	0.014361299	-0.384812472	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; 	"K18270|0|hsa:22930|RAB3GAP1, P130, RAB3GAP, RAB3GAP130, WARBM1; RAB3 GTPase activating protein subunit 1 (catalytic); K18270 Rab3 GTPase-activating protein catalytic subunit (A)"	--	[S]	Function unknown	Rab3 GTPase-activating protein catalytic subunit	Rab3 GTPase-activating protein catalytic subunit GN=RAB3GAP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rab3 GTPase-activating protein catalytic subunit isoform 1 [Ceratotherium simum simum]
ENSG00000115840(SLC25A12)	--	11.7427	571	10.0671	489	11.4085	549	11.3162	553	10.2192	494	8.68137	422	0.970274663	-0.07683343	normal	0.970852559	-0.006729276	normal	0.764087586	-0.386636187	normal	0.557150367	-0.153230071	normal	--	--	--	"K15105|0|hsa:8604|SLC25A12, AGC1, ARALAR; solute carrier family 25 (aspartate/glutamate carrier), member 12; K15105 solute carrier family 25 (mitochondrial aspartate/glutamate transporter), member 12/13 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein;; EF-hand domain pair;; EF hand;; EF-hand domain	Calcium-binding mitochondrial carrier protein Aralar1 GN=SLC25A12 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: calcium-binding mitochondrial carrier protein Aralar1 isoform X1 [Galeopterus variegatus]
ENSG00000115841(RMDN2)	--	2.685277876	73	3.236779502	81	2.9503	70	2.484550206	62	2.804043161	68	2.765753608	74	0.963424387	-0.26050324	normal	0.957455921	-0.26833809	normal	0.973588476	0.070399523	normal	0.817401183	-0.15576529	normal	--	--	--	--	--	--	--	--	Regulator of microtubule dynamics protein 2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: regulator of microtubule dynamics protein 3 isoform X1 [Tupaia chinensis]
ENSG00000115844(DLX2)	--	0.371362557	14	0.159015409	6	0.381383499	14	0.18564033	7	0.076469883	2	0.032498312	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K18488|4.19705e-159|hsa:1746|DLX2, TES-1, TES1; distal-less homeobox 2; K18488 homeobox protein DLX2 (A)"	--	[K]	Transcription	Homeobox domain;; Homeobox protein distal-less-like N terminal	Homeobox protein DLX-2 GN=DLX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein DLX-2 [Ceratotherium simum simum]
ENSG00000115850(LCT)	--	0.0305575	4	0	0	0.0600338	7	0.00766303	1	0.00743223	0	0.00757387	1	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K01229|0|hsa:3938|LCT, LAC, LPH, LPH1; lactase (EC:3.2.1.108 3.2.1.62); K01229 lactase-phlorizin hydrolase [EC:3.2.1.108 3.2.1.62] (A)"	Galactose metabolism (ko00052);; Carbohydrate digestion and absorption (ko04973)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 1	Phlorizin hydrolase (Precursor) GN=LCT OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: lactase-phlorizin hydrolase [Equus przewalskii]
ENSG00000115866(DARS)	--	45.00638824	1846	48.37382883	1997	41.4324011	1690	31.9542111	1319	27.98206725	1142	28.13376109	1144	0.272233575	-0.515280201	normal	0.000188034	-0.826858857	normal	0.10688703	-0.570602985	normal	6.23E-06	-0.639971157	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	K01876|0|pps:100967244|DARS; aspartyl-tRNA synthetase; K01876 aspartyl-tRNA synthetase [EC:6.1.1.12] (A)	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class II (D, K and N);; OB-fold nucleic acid binding domain;; tRNA synthetases class II core domain (F)"	"Aspartate--tRNA ligase, cytoplasmic GN=DARS OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: aspartate--tRNA ligase, cytoplasmic [Mustela putorius furo] "
ENSG00000115875(SRSF7)	--	94.704735	2193	91.4599819	2197	110.7233126	2592	93.30576	2194	87.971743	2114	79.984793	1898	0.987487154	-0.030153429	normal	0.985690456	-0.076932061	normal	0.555853915	-0.457563884	normal	0.300600362	-0.191277191	normal	[R]	General function prediction only	--	"K12896|2.47749e-60|acs:100557149|srsf7; serine/arginine-rich splicing factor 7; K12896 splicing factor, arginine/serine-rich 7 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Serine/arginine-rich splicing factor 7 GN=SRSF7 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 7 isoform X2 [Eptesicus fuscus]
ENSG00000115884(SDC1)	--	125.7620163	7373	125.848478	7500	125.4618552	7610	115.7368801	6770	99.78699326	5895	98.86789517	5862	0.991851473	-0.153894704	normal	0.920250642	-0.368741248	normal	0.894974741	-0.384707563	normal	0.085431545	-0.300835216	normal	--	--	--	"K06257|1.53327e-154|hsa:6382|SDC1, CD138, SDC, SYND1, syndecan; syndecan 1; K06257 syndecan 1 (A)"	ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Malaria (ko05144);; Proteoglycans in cancer (ko05205)	--	--	Syndecan domain	Syndecan-1 (Precursor) GN=SDC1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: syndecan-1 [Felis catus]
ENSG00000115896(PLCL1)	--	0	0	0	0	0	0	0.034843887	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K15375|0|hsa:5334|PLCL1, PLCE, PLCL, PLDL1, PPP1R127, PRIP; phospholipase C-like 1; K15375 inactive phospholipase C-like protein 1 (A)"	GABAergic synapse (ko04727)	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain"	Inactive phospholipase C-like protein 1 GN=PLCL1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: inactive phospholipase C-like protein 1 [Leptonychotes weddellii]
ENSG00000115902(SLC1A4)	--	9.681921616	793	10.553771	862	7.846626	640	5.136857936	416	4.900969431	394	9.96986669	797	1.16E-05	-0.958956936	normal	3.32E-08	-1.147861019	down	0.887022471	0.307563891	normal	0.271634135	-0.533791788	normal	[C]	Energy production and conversion	Molecular Function: symporter activity (GO:0015293);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05615|0|ptr:459278|SLC1A4; solute carrier family 1 (glutamate/neutral amino acid transporter), member 4; K05615 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 (A)"	--	[E]	Amino acid transport and metabolism	Sodium:dicarboxylate symporter family	Neutral amino acid transporter A GN=SLC1A4 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: neutral amino acid transporter A isoform 1 [Ceratotherium simum simum]
ENSG00000115904(SOS1)	--	12.59794149	1520	13.77818225	1680	16.74367	1786	10.2767279	1375	10.82567658	1362	11.83641003	1439	0.970872449	-0.17528557	normal	0.894499828	-0.32383666	normal	0.898935329	-0.319654775	normal	0.100137948	-0.276641264	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K03099|0|hsa:6654|SOS1, GF1, GGF1, GINGF, HGF, NS4; son of sevenless homolog 1 (Drosophila); K03099 son of sevenless (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; Dorso-ventral axis formation (ko04320);; Focal adhesion (ko04510);; Gap junction (ko04540);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Neurotrophin signaling pathway (ko04722);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Alcoholism (ko05034);; Hepatitis C (ko05160);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; RhoGEF domain;; PH domain;; Core histone H2A/H2B/H3/H4	Son of sevenless homolog 1 GN=SOS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: son of sevenless homolog 1 [Orcinus orca]
ENSG00000115919(KYNU)	--	218.0098587	6079	219.3166832	6407	220.255369	6049	173.0993143	4904	165.0597912	4546	190.8881883	5814	0.934940509	-0.340611235	normal	0.417034149	-0.51633241	normal	0.993711208	-0.065440342	normal	0.077955482	-0.300904057	normal	[E]	Amino acid transport and metabolism	--	K01556|0|ptr:459641|KYNU; kynureninase; K01556 kynureninase [EC:3.7.1.3] (A)	Tryptophan metabolism (ko00380)	[E]	Amino acid transport and metabolism	Aminotransferase class-V	Kynureninase {ECO:0000255|HAMAP-Rule:MF_03017} OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: kynureninase [Trichechus manatus latirostris]
ENSG00000115935(WIPF1)	--	6.72741527	401	13.79764458	338	5.72618647	302	9.0177048	492	10.69122079	654	7.843934152	540	0.91891978	0.263311762	normal	7.72E-05	0.927804907	normal	0.001278065	0.82697994	normal	0.001966435	0.674523045	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	--	--	[Z]	Cytoskeleton	WH2 motif	WAS/WASL-interacting protein family member 1 GN=WIPF1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: WAS/WASL-interacting protein family member 1 isoform X1 [Loxodonta africana] 
ENSG00000115942(ORC2)	--	13.552778	967	13.62081146	971	14.30952365	1005	9.141797668	657	8.645184549	616	7.957755324	528	0.089561487	-0.587314869	normal	0.016887792	-0.676632294	normal	1.33E-05	-0.934902088	normal	2.18E-06	-0.730246342	normal	[L]	"Replication, recombination and repair"	Cellular Component: origin recognition complex (GO:0000808);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; 	"K02604|0|hsa:4999|ORC2, ORC2L; origin recognition complex, subunit 2; K02604 origin recognition complex subunit 2 (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	Origin recognition complex subunit 2	Origin recognition complex subunit 2 GN=ORC2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: origin recognition complex subunit 2 isoform X1 [Panthera tigris altaica] 
ENSG00000115944(COX7A2L)	--	162.9646365	2331	149.6338119	2162	143.3099607	2051	122.740228	1785	117.2429283	1647	127.1755768	1833	0.712835293	-0.415543123	normal	0.727859717	-0.413619915	normal	0.976475152	-0.170279261	normal	0.034351161	-0.335030282	normal	--	--	--	K02270|5.09456e-78|ptr:459181|COX7A2L; cytochrome c oxidase subunit VIIa polypeptide 2 like; K02270 cytochrome c oxidase subunit 7a (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	Cytochrome c oxidase subunit VIIa	"Cytochrome c oxidase subunit 7A-related protein, mitochondrial (Precursor) GN=COX7A2L OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: cytochrome c oxidase subunit 7A-related protein, mitochondrial-like [Equus caballus] "
ENSG00000115946(PNO1)	--	30.59976	1097	27.61894	1008	32.9787	1112	23.19547	855	25.19517	875	17.7820309	674	0.746902935	-0.389779232	normal	0.948583929	-0.225204275	normal	0.003518307	-0.729340091	normal	0.005914622	-0.441968551	normal	[R]	General function prediction only	--	"K11884|8.24109e-176|hsa:56902|PNO1, KHRBP1, RRP20; partner of NOB1 homolog (S. cerevisiae); K11884 RNA-binding protein PNO1 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	KH domain	RNA-binding protein PNO1 GN=PNO1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein PNO1 [Condylura cristata]
ENSG00000115947(ORC4)	--	19.98035521	765	19.820694	819	23.7064204	731	16.961189	583	14.8918024	544	16.116753	582	0.652004882	-0.421822232	normal	0.074492268	-0.610290357	normal	0.849970182	-0.336362062	normal	0.008261045	-0.459239513	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	"K02606|0|pps:100977800|ORC4; origin recognition complex, subunit 4; K02606 origin recognition complex subunit 4 (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	Origin recognition complex (ORC) subunit 4 C-terminus;; AAA ATPase domain;; ATPase family associated with various cellular activities (AAA);; AAA domain;; Archaeal ATPase;; NACHT domain	Origin recognition complex subunit 4 GN=ORC4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: origin recognition complex subunit 4 isoform X3 [Galeopterus variegatus] 
ENSG00000115963(RND3)	--	27.94712455	1315	38.26068587	1797	36.53787723	1672	41.97888861	1958	36.19939508	1698	44.79123449	2109	0.177664449	0.542962749	normal	0.981975123	-0.10309124	normal	0.89832839	0.32642936	normal	0.283695781	0.248138588	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07859|6.08993e-172|tup:102481034|rho-related GTP-binding protein RhoE-like; K07859 Rho family GTPase 3 (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoE (Precursor) GN=RND3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoE-like [Myotis brandtii] 
ENSG00000115966(ATF2)	--	16.14541539	997	19.94237137	1200	18.69189277	1130	12.46568572	737	12.67735328	720	14.16180844	872	0.477337562	-0.465922423	normal	0.002004936	-0.75714615	normal	0.769866751	-0.381631072	normal	0.000518904	-0.535206295	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K04450|0|pps:100985706|ATF2, CHN1; activating transcription factor 2; K04450 cyclic AMP-dependent transcription factor ATF-2 (A)"	MAPK signaling pathway (ko04010);; cGMP-PKG signaling pathway (ko04022);; PI3K-Akt signaling pathway (ko04151);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Thyroid hormone synthesis (ko04918);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper	Cyclic AMP-dependent transcription factor ATF-2 GN=ATF2 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: cyclic AMP-dependent transcription factor ATF-2 isoformX1 [Canis lupus familiaris] 
ENSG00000115970(THADA)	--	15.02805606	1591	14.11686648	1486	15.08932011	1579	10.92547632	1187	11.25557015	1195	11.5453775	1221	0.537372819	-0.452937698	normal	0.874408021	-0.335468498	normal	0.791339504	-0.378825632	normal	0.012015442	-0.390933305	normal	[S]	Function unknown	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Putative death-receptor fusion protein (DUF2428);; HEAT repeat	Thyroid adenoma-associated protein GN=THADA OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: thyroid adenoma-associated protein [Trichechus manatus latirostris]
ENSG00000115977(AAK1)	--	7.8466518	1543	9.045164606	1691	9.187790828	1807	6.85774042	1277	6.101685182	1216	5.413374648	1035	0.909988732	-0.303479024	normal	0.373341126	-0.496633653	normal	0.000232998	-0.811348107	normal	0.00023359	-0.536463587	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08853|0|pon:100939328|AAK1; AP2 associated kinase 1; K08853 AP2-associated kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	AP2-associated protein kinase 1 GN=AAK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: AP2-associated protein kinase 1 isoform X2 [Equus caballus]
ENSG00000115993(TRAK2)	--	8.533548432	989	9.4159084	1054	8.612027	978	7.6224343	884	7.09699	785	6.55683085	759	0.959249114	-0.192439972	normal	0.576788005	-0.445792772	normal	0.78582679	-0.37336883	normal	0.050748255	-0.337027634	normal	--	--	--	"K15374|0|hsa:66008|TRAK2, ALS2CR3, CALS-C, GRIF-1, GRIF1, MILT2, OIP98; trafficking protein, kinesin binding 2; K15374 trafficking kinesin-binding protein 2 (A)"	GABAergic synapse (ko04727)	[S]	Function unknown	HAP1 N-terminal conserved region;; Kinesin associated protein	Trafficking kinesin-binding protein 2 GN=TRAK2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: trafficking kinesin-binding protein 2 isoform X2 [Galeopterus variegatus]
ENSG00000115998(C2orf42)	--	5.876584091	232	4.412114877	186	3.848106	172	3.28495488	156	4.30521261	163	4.5681444	191	0.349459299	-0.598542477	normal	0.946940526	-0.210031467	normal	0.95941409	0.141689956	normal	0.535298568	-0.23109163	normal	--	--	--	--	--	--	--	"Putative treble-clef, zinc-finger, Zn-binding"	Uncharacterized protein C2orf42 GN=C2orf42 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C2orf42 homolog [Pteropus alecto] 
ENSG00000116001(TIA1)	--	22.215756	1905	24.49326429	2022	24.97196311	1870	20.53740491	1625	19.81422656	1590	21.24492548	1634	0.948080633	-0.259956235	normal	0.8377284	-0.367871685	normal	0.968383566	-0.202746181	normal	0.094283328	-0.278898249	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13201|0|pps:100970193|TIA1; TIA1 cytotoxic granule-associated RNA binding protein; K13201 nucleolysin TIA-1/TIAR (A)	--	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Calcipressin;; RNA binding motif"	Nucleolysin TIA-1 isoform p40 GN=TIA1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: nucleolysin TIA-1 isoform p40 isoform X1 [Chrysochloris asiatica]
ENSG00000116005(PCYOX1)	--	45.06267912	3942	47.48907456	3988	44.4783002	3907	36.74403176	3154	32.91440285	2938	35.37965053	3157	0.899498836	-0.352423438	normal	0.611378682	-0.462052566	normal	0.936637285	-0.315662242	normal	0.01547387	-0.377179653	normal	--	--	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor (GO:0016670);; Biological Process: prenylcysteine catabolic process (GO:0030328);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K05906|0|hsa:51449|PCYOX1, PCL1; prenylcysteine oxidase 1 (EC:1.8.3.5); K05906 prenylcysteine oxidase / farnesylcysteine lyase [EC:1.8.3.5 1.8.3.6] (A)"	Terpenoid backbone biosynthesis (ko00900)	--	--	Prenylcysteine lyase;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; Flavin containing amine oxidoreductase	Prenylcysteine oxidase 1 (Precursor) GN=PCYOX1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: prenylcysteine oxidase 1 [Galeopterus variegatus]
ENSG00000116014(KISS1R)	--	0.852048343	14	0.8325475	14	0.888525847	17	0.748327202	9	1.929125682	21	0.3069716	5	--	--	--	0.981489886	0.517638856	normal	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08374|0|hsa:84634|KISS1R, AXOR12, CPPB1, GPR54, HH8, HOT7T175, KISS-1R; KISS1 receptor; K08374 KISS1 receptor (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	KiSS-1 receptor GN=KISS1R OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kiSS-1 receptor [Chrysochloris asiatica]
ENSG00000116016(EPAS1)	--	80.446602	8069	75.357228	7521	84.88251	8451	85.119743	8486	66.872853	6692	119.737013	12058	0.99547763	0.041854754	normal	0.989319538	-0.189873107	normal	0.553262406	0.504429269	normal	0.764410862	0.15999981	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09095|0|hsa:2034|EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73; endothelial PAS domain protein 1; K09095 hypoxia-inducible factor 2 alpha (A)"	Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[TK]	Signal transduction mechanisms;; Transcription	PAS domain;; PAS fold;; HIF-1 alpha C terminal transactivation domain;; Hypoxia-inducible factor-1;; PAS fold;; PAS domain;; PAS fold	Endothelial PAS domain-containing protein 1 GN=EPAS1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: endothelial PAS domain-containing protein 1 isoform 2 [Ceratotherium simum simum]
ENSG00000116017(ARID3A)	--	4.428988034	521	4.346110097	524	4.392524423	529	3.979506253	467	2.841349009	334	4.392850064	519	0.951222392	-0.188106763	normal	0.041924423	-0.668706331	normal	0.971758139	-0.035721525	normal	0.2560645	-0.274879963	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	ARID/BRIGHT DNA binding domain	AT-rich interactive domain-containing protein 3A GN=ARID3A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 3A [Trichechus manatus latirostris]
ENSG00000116030(SUMO1)	--	135.4328659	3005	136.4870168	3077	139.2485246	3058	98.35600846	2165	90.84071725	1928	94.12730778	2062	0.352689927	-0.503525388	normal	0.007162185	-0.695409993	normal	0.101811061	-0.576486019	normal	2.82E-05	-0.591813261	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K12160|2.65199e-61|ssc:100127139|SUMO1, pigSUMO1; SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae); K12160 small ubiquitin-related modifier (A)"	RNA transport (ko03013)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin family	Small ubiquitin-related modifier 1 (Precursor) GN=SUMO1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	Small ubiquitin-related modifier 1 [Bos mutus]
ENSG00000116031(CD207)	--	0.0599402	2	0	0	0	0	0.0297583	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06561|0|hsa:50489|CD207, CLEC4K; CD207 molecule, langerin; K06561 CD207 antigen (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 4 member K GN=CD207 OS=Homo sapiens (Human) PE=1 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 4 member K [Ceratotherium simum simum]
ENSG00000116032(GRIN3B)	--	2.73849	147	1.91078	105	1.21234	68	1.30793	70	1.47445	79	1.21344	66	0.003218069	-1.084407993	down	0.897494215	-0.424812206	normal	0.974863048	-0.050226304	normal	0.304170864	-0.595904151	normal	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05214|0|hsa:116444|GRIN3B, GluN3B, NR3B; glutamate receptor, ionotropic, N-methyl-D-aspartate 3B; K05214 glutamate receptor ionotropic, NMDA 3B (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033);; Alcoholism (ko05034)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site"	"Glutamate receptor ionotropic, NMDA 3B (Precursor) GN=GRIN3B OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, NMDA 3B [Eptesicus fuscus]"
ENSG00000116035(VAX2)	--	2.757576	203	2.593566253	214	3.240523292	171	1.9229445	146	3.290523168	181	3.4994532	201	0.669151982	-0.501842382	normal	0.929515891	-0.261039143	normal	0.944309845	0.22308618	normal	0.656865936	-0.175841199	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09318|2.46452e-137|ptr:470400|VAX2; ventral anterior homeobox 2; K09318 homeobox protein ventral anterior (A)	--	[K]	Transcription	Homeobox domain	Ventral anterior homeobox 2 GN=VAX2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: ventral anterior homeobox 2 [Trichechus manatus latirostris]
ENSG00000116039(ATP6V1B1)	--	1.209307859	44	0.998768301	23	1.045401118	38	0.765011872	24	0.822339588	29	0.85762076	31	0.816718996	-0.8638479	normal	0.981434248	0.295650606	normal	0.977387083	-0.289256237	normal	0.6615276	-0.341966268	normal	[C]	Energy production and conversion	Molecular Function: ATP binding (GO:0005524);; Biological Process: proton transport (GO:0015992);; Biological Process: ATP metabolic process (GO:0046034);; 	"K02147|0|hsa:525|ATP6V1B1, ATP6B1, RTA1B, VATB, VMA2, VPP3; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1 (EC:3.6.3.14); K02147 V-type H+-transporting ATPase subunit B (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	"ATP synthase alpha/beta family, nucleotide-binding domain;; ATP synthase alpha/beta chain, C terminal domain;; ATP synthase alpha/beta family, beta-barrel domain"	"V-type proton ATPase subunit B, kidney isoform GN=ATP6V1B1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: V-type proton ATPase subunit B, kidney isoform [Ursus maritimus]"
ENSG00000116044(NFE2L2)	--	38.79004706	1824	41.95267734	1972	40.62100629	1946	25.29803969	1173	26.70250129	1258	35.37615054	1711	0.01202098	-0.667028099	normal	0.014066067	-0.669305789	normal	0.971199783	-0.193802653	normal	0.01005203	-0.491257823	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K05638|0|ptr:742622|NFE2L2; nuclear factor, erythroid 2-like 2; K05638 nuclear factor erythroid 2-related factor 2 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[K]	Transcription	bZIP Maf transcription factor;; bZIP transcription factor;; Basic region leucine zipper	Nuclear factor erythroid 2-related factor 2 GN=NFE2L2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nuclear factor erythroid 2-related factor 2 isoform X2 [Lipotes vexillifer]
ENSG00000116062(MSH6)	--	59.82520707	4734	55.93365488	4425	63.27893411	4738	39.42347422	3151	44.41855766	3489	31.45455115	2482	0.046183264	-0.617834559	normal	0.895121633	-0.364149892	normal	1.94E-06	-0.940644318	normal	1.01E-05	-0.629023038	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	"K08737|0|hsa:2956|MSH6, GTBP, GTMBP, HNPCC5, HSAP, p160; mutS homolog 6; K08737 DNA mismatch repair protein MSH6 (A)"	Mismatch repair (ko03430);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210)	[L]	"Replication, recombination and repair"	MutS domain V;; MutS domain III;; MutS domain I;; PWWP domain;; MutS family domain IV;; MutS domain II	DNA mismatch repair protein Msh6 GN=MSH6 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA mismatch repair protein Msh6 isoform 1 [Orcinus orca]
ENSG00000116095(PLEKHA3)	--	9.527810712	497	12.04343041	491	13.13110063	499	8.131091212	365	6.295551216	292	7.378451105	402	0.51503963	-0.474462419	normal	0.006800156	-0.768077277	normal	0.873417606	-0.319056259	normal	0.010506884	-0.510674786	normal	--	--	--	--	--	--	--	PH domain;; Pleckstrin homology domain	Pleckstrin homology domain-containing family A member 3 GN=PLEKHA3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family A member 3 isoform X1 [Panthera tigris altaica]
ENSG00000116096(SPR)	--	67.467	1683	71.6833	1846	77.828	2001	53.6177	1355	51.7765	1282	53.0565	1335	0.864353414	-0.343224569	normal	0.185061202	-0.546892017	normal	0.06961496	-0.591621614	normal	0.000659655	-0.498457203	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00072|4.11754e-156|hsa:6697|SPR, SDR38C1; sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) (EC:1.1.1.153); K00072 sepiapterin reductase [EC:1.1.1.153] (A)"	Folate biosynthesis (ko00790)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain	Sepiapterin reductase GN=SPR OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: sepiapterin reductase [Ceratotherium simum simum]
ENSG00000116106(EPHA4)	--	1.248773321	112	0.718906137	76	2.045882281	71	1.69134562	169	2.305573355	271	1.46856318	174	0.621833288	0.556439716	normal	4.82E-12	1.792666236	up	5.82E-05	1.267105375	up	0.005620559	1.224029364	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05105|0|ptr:470660|EPHA4; EPH receptor A4; K05105 Eph receptor A4 [EC:2.7.10.1] (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Ephrin type-A receptor 4 (Precursor) GN=EPHA4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 4 isoform X1 [Tupaia chinensis]
ENSG00000116117(PARD3B)	--	2.445877129	363	2.970302232	415	3.0417605	427	1.54446648	234	1.415946039	219	2.282622505	351	0.080468818	-0.660779404	normal	0.000270552	-0.938814191	normal	0.901763403	-0.289922053	normal	0.016716494	-0.603611216	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Domain of unknown function (DUF3534);; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Partitioning defective 3 homolog B GN=PARD3B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: partitioning defective 3 homolog B isoform X1 [Bos taurus] 
ENSG00000116120(FARSB)	--	34.96407472	1487	32.80591612	1383	35.34698893	1478	28.80237177	1219	23.76736006	1057	19.0745827	809	0.894068363	-0.317176108	normal	0.712976905	-0.40873939	normal	3.93E-05	-0.876495184	normal	0.001937252	-0.517395797	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: phenylalanine-tRNA ligase activity (GO:0004826);; Molecular Function: ATP binding (GO:0005524);; Biological Process: phenylalanyl-tRNA aminoacylation (GO:0006432);; 	"K01890|0|hsa:10056|FARSB, FARSLB, FRSB, PheHB, PheRS; phenylalanyl-tRNA synthetase, beta subunit (EC:6.1.1.20); K01890 phenylalanyl-tRNA synthetase beta chain [EC:6.1.1.20] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	B3/4 domain;; tRNA synthetase B5 domain	Phenylalanine--tRNA ligase beta subunit GN=FARSB OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: phenylalanine--tRNA ligase beta subunit [Galeopterus variegatus]
ENSG00000116127(ALMS1)	--	3.023029023	797	3.686413976	933	3.47085669	880	2.447405787	647	2.955949391	792	2.253329728	595	0.857852531	-0.330936669	normal	0.931450434	-0.257349873	normal	0.126347729	-0.571702642	normal	0.029138849	-0.381025476	normal	--	--	--	"K16741|0|hsa:7840|ALMS1, ALSS; Alstrom syndrome 1; K16741 alstrom syndrome protein 1 (A)"	--	--	--	ALMS motif	Alstrom syndrome protein 1 GN=ALMS1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: Alstrom syndrome protein 1 [Galeopterus variegatus]
ENSG00000116128(BCL9)	--	5.964439121	810	4.792931654	648	4.95144816	670	3.5189521	470	4.173627409	560	3.244614235	441	0.000623006	-0.814039407	normal	0.938063271	-0.231411986	normal	0.079922811	-0.609964219	normal	0.002248848	-0.554061035	normal	--	--	--	--	--	--	--	B-cell lymphoma 9 protein	B-cell CLL/lymphoma 9 protein GN=BCL9 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: B-cell CLL/lymphoma 9 protein [Ceratotherium simum simum]
ENSG00000116132(PRRX1)	--	0.118912363	8	0.141995677	7	0	0	0.0363537	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K09329|2.16554e-171|ptr:736677|PRRX1; paired related homeobox 1; K09329 paired mesoderm homeobox protein (A)	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Paired mesoderm homeobox protein 1 GN=PRRX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: paired mesoderm homeobox protein 1 isoform 1 [Equus caballus] 
ENSG00000116133(DHCR24)	--	61.426165	5133	66.46013	5569	67.9067	5681	35.605259	2958	34.076207	2821	62.6354482	5220	0.000109856	-0.825682451	normal	3.14E-07	-1.002248057	down	0.991238169	-0.130350327	normal	0.078631235	-0.59420837	normal	[C]	Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K09828|0|hsa:1718|DHCR24, DCE, Nbla03646, SELADIN1, seladin-1; 24-dehydrocholesterol reductase (EC:1.3.1.72); K09828 delta24-sterol reductase [EC:1.3.1.72] (A)"	Steroid biosynthesis (ko00100)	[R]	General function prediction only	FAD binding domain	Delta(24)-sterol reductase (Precursor) GN=DHCR24 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: delta(24)-sterol reductase [Mustela putorius furo] 
ENSG00000116138(DNAJC16)	--	4.75195374	465	5.600326587	548	5.552021331	523	6.4894582	625	6.3685952	595	6.63318177	625	0.739287772	0.394664929	normal	0.96813454	0.0970302	normal	0.929598014	0.248096752	normal	0.264088999	0.243257402	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell redox homeostasis (GO:0045454);; 	"K09536|0|pps:100991876|DNAJC16; DnaJ (Hsp40) homolog, subfamily C, member 16; K09536 DnaJ homolog subfamily C member 16 (A)"	--	--	--	DnaJ domain;; Thioredoxin	DnaJ homolog subfamily C member 16 (Precursor) GN=DNAJC16 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: dnaJ homolog subfamily C member 16 [Ceratotherium simum simum]
ENSG00000116141(MARK1)	--	1.597007429	127	1.47902221	130	1.992932308	173	1.092855413	81	1.130543174	81	0.70001888	58	0.489624315	-0.669435089	normal	0.417397031	-0.693623724	normal	2.53E-07	-1.560219297	down	0.002738529	-0.988346925	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08798|0|hsa:4139|MARK1, MARK, Par-1c, Par1c; MAP/microtubule affinity-regulating kinase 1 (EC:2.7.11.1 2.7.11.26); K08798 MAP/microtubule affinity-regulating kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase associated domain 1;; Kinase-like	Serine/threonine-protein kinase MARK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase MARK1 [Oryctolagus cuniculus]
ENSG00000116151(MORN1)	--	3.13504028	195	4.66952011	209	3.836503042	184	2.978272964	165	3.491396664	145	3.550225935	192	0.930378916	-0.269528412	normal	0.557496973	-0.544121792	normal	0.966088571	0.052685181	normal	0.497432075	-0.249099362	normal	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat	MORN repeat-containing protein 1 GN=MORN1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: MORN repeat-containing protein 1 isoform X1 [Tupaia chinensis]
ENSG00000116157(GPX7)	--	0	0	0	0	0	0	0.0979148	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: glutathione peroxidase activity (GO:0004602);; Biological Process: response to oxidative stress (GO:0006979);; Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00432|4.69539e-123|ptr:469325|GPX7; glutathione peroxidase 7 (EC:1.11.1.9); K00432 glutathione peroxidase [EC:1.11.1.9] (A)	Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590);; Thyroid hormone synthesis (ko04918)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glutathione peroxidase;; AhpC/TSA family	Glutathione peroxidase 7 (Precursor) GN=GPX7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione peroxidase 7 [Felis catus]
ENSG00000116161(CACYBP)	--	93.82468776	2096	49.39844357	2190	58.6427101	2532	59.3584682	2481	53.89598496	2108	45.16940326	1771	0.971006049	0.212307585	normal	0.985681509	-0.076428762	normal	0.254581091	-0.523628627	normal	0.66433168	-0.12223664	normal	--	--	--	K04507|4.39783e-165|ggo:101148490|CACYBP; calcyclin-binding protein isoform 1; K04507 calcyclin binding protein (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	"Siah interacting protein, N terminal;; SGS domain;; CS domain"	Calcyclin-binding protein GN=CACYBP OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcyclin-binding protein [Vicugna pacos]
ENSG00000116171(SCP2)	--	45.04743202	1333	41.9022856	1343	40.82335911	1209	44.51123709	1200	45.99449963	1256	41.95657935	1258	0.967144602	-0.182253094	normal	0.976977183	-0.117912067	normal	0.981164224	0.048966188	normal	0.718350231	-0.086151235	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K08764|0|ggo:101143883|SCP2; non-specific lipid-transfer protein isoform 1; K08764 sterol carrier protein 2 [EC:2.3.1.176] (A)	Primary bile acid biosynthesis (ko00120);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	"SCP-2 sterol transfer family;; Thiolase, C-terminal domain;; Thiolase, N-terminal domain;; Alkyl sulfatase C-terminal;; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III"	Non-specific lipid-transfer protein GN=SCP2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	non-specific lipid-transfer protein [Oryctolagus cuniculus] 
ENSG00000116176(TPSG1)	--	0.058815	1	0	0	0	0	0	0	0.170909	2	0.057006	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09615|0|hsa:25823|TPSG1, PRSS31, TMT, trpA; tryptase gamma 1 (EC:3.4.21.59); K09615 tryptase gamma 1 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin	Tryptase gamma heavy chain (Precursor) GN=TPSG1 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tryptase gamma [Equus caballus]
ENSG00000116183(PAPPA2)	--	0.0108333	2	0.01073686	2	0.023581205	4	0.00479248	1	0	0	0.00953606	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08647|0|hsa:60676|PAPPA2, PAPP-A2, PAPP-E, PAPPE, PLAC3; pappalysin 2; K08647 pappalysin-2 [EC:3.4.24.-] (A)"	--	--	--	Concanavalin A-like lectin/glucanases superfamily;; LNR domain;; Sushi domain (SCR repeat);; Pregnancy-associated plasma protein-A;; Laminin G domain	Pappalysin-2 (Precursor) GN=PAPPA2 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: pappalysin-2 [Ceratotherium simum simum]
ENSG00000116191(RALGPS2)	--	9.99949061	943	8.074169546	738	13.02848797	908	14.32691055	1177	11.74110708	846	8.166029141	598	0.913922154	0.288530904	normal	0.960456024	0.175274632	normal	0.062190847	-0.609577896	normal	0.999953667	-0.005322404	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[T]	Signal transduction mechanisms	RasGEF domain	Ras-specific guanine nucleotide-releasing factor RalGPS2 GN=RALGPS2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras-specific guanine nucleotide-releasing factor RalGPS2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000116194(ANGPTL1)	--	0.021851	1	0.117750144	7	0.0981972	5	0.016596598	1	0	0	0.016481308	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-related protein 1 (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: angiopoietin-related protein 1 isoform X1 [Physeter catodon]
ENSG00000116198(CEP104)	--	6.585899975	678	8.818868427	725	7.038505364	692	7.20126	705	7.685028742	640	7.694227647	746	0.974980392	0.025449166	normal	0.951229645	-0.200889302	normal	0.971352603	0.099901835	normal	0.947441852	-0.023861542	normal	--	--	--	"K16458|0|hsa:9731|CEP104, GlyBP, KIAA0562; centrosomal protein 104kDa; K16458 centrosomal protein CEP104 (A)"	--	[T]	Signal transduction mechanisms	--	Centrosomal protein of 104 kDa GN=CEP104 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: centrosomal protein of 104 kDa isoform X1 [Tupaia chinensis] 
ENSG00000116199(FAM20B)	--	15.77243	1675	15.26357914	1638	14.89591795	1561	14.69611603	1562	13.82085	1459	12.90879	1358	0.978879878	-0.131473982	normal	0.969278928	-0.188197801	normal	0.963168547	-0.209061162	normal	0.35943966	-0.176217221	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1193)	Glycosaminoglycan xylosylkinase GN=FAM20B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: glycosaminoglycan xylosylkinase [Tupaia chinensis]
ENSG00000116205(TCEANC2)	--	1.187630422	215	1.027215966	187	1.37584859	238	1.475314211	282	1.595787416	267	1.56246127	220	0.854569998	0.358284928	normal	0.627628446	0.489049264	normal	0.960857737	-0.120949905	normal	0.447482345	0.243356941	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	--	--	[K]	Transcription	TFIIS helical bundle-like domain	Transcription elongation factor A N-terminal and central domain-containing protein 2 GN=TCEANC2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription elongation factor A N-terminal and central domain-containing protein 2 isoform X1 [Equus przewalskii]
ENSG00000116209(TMEM59)	--	59.07075484	1315	60.55238809	1221	60.68942646	1271	67.30298831	1431	67.43089075	1532	74.2091896	1657	0.980247217	0.091026642	normal	0.909399975	0.30558802	normal	0.805273463	0.373927378	normal	0.135927174	0.258517953	normal	--	--	--	--	--	--	--	Brain specific membrane anchored protein	Transmembrane protein 59 (Precursor) GN=TMEM59 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 59 isoform X1 [Vicugna pacos]
ENSG00000116212(LRRC42)	--	21.44325956	647	20.487729	640	17.82308458	553	16.46139026	496	15.52815922	474	13.37495788	402	0.686569223	-0.413133555	normal	0.570945018	-0.453361507	normal	0.528352091	-0.466871421	normal	0.018696648	-0.445472449	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine Rich repeats (2 copies);; Leucine Rich repeat	Leucine-rich repeat-containing protein 42 GN=LRRC42 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 42 [Ceratotherium simum simum]
ENSG00000116213(WRAP73)	--	10.854738	303	10.051152	266	10.87215835	300	9.916968	260	11.158937	301	9.612041012	267	0.928523553	-0.250266789	normal	0.954655361	0.156076143	normal	0.952037852	-0.175475987	normal	0.811092715	-0.090642292	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	WD repeat-containing protein WRAP73 GN=WRAP73 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: WD repeat-containing protein WRAP73 [Equus przewalskii]
ENSG00000116221(MRPL37)	--	53.259381	1321	50.979383	1278	51.251351	1288	52.81077109	1336	47.837114	1184	54.728868	1379	0.982682961	-0.014525923	normal	0.974753761	-0.131483615	normal	0.980013121	0.09009617	normal	0.959389613	-0.016711788	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: mitochondrion (GO:0005739);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K17418|0|hsa:51253|MRPL37, L37mt, MRP-L2, MRP-L37, MRPL2, RPML2; mitochondrial ribosomal protein L37; K17418 large subunit ribosomal protein L37 (A)"	--	--	--	Mitochondrial 28S ribosomal protein S30 (PDCD9)	"39S ribosomal protein L37, mitochondrial (Precursor) GN=MRPL37 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"Chain a, Structure Of The Large Subunit Of The Mammalian Mitochondrial Ribosome, Part 2 Of 2"
ENSG00000116237(ICMT)	--	31.5063	2556	29.6249	2411	31.6107	2554	39.4332	3207	35.9261	2911	34.575	2818	0.942641261	0.296344948	normal	0.963309417	0.250313566	normal	0.984829586	0.133546337	normal	0.195261424	0.22716653	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity (GO:0004671);; Biological Process: C-terminal protein methylation (GO:0006481);; Cellular Component: integral component of membrane (GO:0016021);; 	"K00587|1.50445e-180|hsa:23463|ICMT, HSTE14, MST098, MSTP098, PCCMT, PCMT, PPMT; isoprenylcysteine carboxyl methyltransferase (EC:2.1.1.100); K00587 protein-S-isoprenylcysteine O-methyltransferase [EC:2.1.1.100] (A)"	Terpenoid backbone biosynthesis (ko00900)	[O]	"Posttranslational modification, protein turnover, chaperones"	Isoprenylcysteine carboxyl methyltransferase (ICMT) family;; Phospholipid methyltransferase	Protein-S-isoprenylcysteine O-methyltransferase GN=ICMT OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-S-isoprenylcysteine O-methyltransferase [Bubalus bubalis]
ENSG00000116251(RPL22)	--	165.6788363	4766	171.2159137	4842	166.0732427	4681	206.123904	5944	168.5248818	5306	171.5097895	5208	0.965791464	0.287739704	normal	0.991401721	0.110562044	normal	0.989684424	0.145576634	normal	0.350870553	0.182215453	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02891|2.18501e-51|acs:100557258|rpl22; ribosomal protein L22; K02891 large subunit ribosomal protein L22e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L22e protein family	60S ribosomal protein L22 GN=RPL22 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L22 [Ornithorhynchus anatinus]
ENSG00000116254(CHD5)	--	0.2877199	56	0.293193416	59	0.143712667	33	0.585870355	64	0.6109023	90	0.360726062	82	0.973572004	0.157762051	normal	0.815930686	0.575755556	normal	0.014703973	1.266843656	normal	0.165648091	0.651910348	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14435|0|hsa:26038|CHD5, CHD-5; chromodomain helicase DNA binding protein 5 (EC:3.6.4.12); K14435 chromodomain-helicase-DNA-binding protein 5 [EC:3.6.4.12] (A)"	--	[R]	General function prediction only	"CHDCT2 (NUC038) domain;; SNF2 family N-terminal domain;; Domain of Unknown Function (DUF1086);; CHDNT (NUC034) domain;; Domain of Unknown Function (DUF1087);; PHD-finger;; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain;; Class II histone deacetylase complex subunits 2 and 3;; Type III restriction enzyme, res subunit"	Chromodomain-helicase-DNA-binding protein 5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: chromodomain-helicase-DNA-binding protein 5 [Odobenus rosmarus divergens]
ENSG00000116260(QSOX1)	--	62.062888	4130	47.7728371	3283	55.83997877	3746	96.2941512	6364	73.69773561	4940	62.05109286	4056	0.095712639	0.592780892	normal	0.166860813	0.567855118	normal	0.989904176	0.106374031	normal	0.168578689	0.438448395	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Molecular Function: thiol oxidase activity (GO:0016972);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; 	K10758|0|pps:100974942|QSOX1; quiescin Q6 sulfhydryl oxidase 1; K10758 thiol oxidase [EC:1.8.3.2] (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Erv1 / Alr family;; Thioredoxin	Sulfhydryl oxidase 1 (Precursor) GN=QSOX1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: sulfhydryl oxidase 1, partial [Galeopterus variegatus]"
ENSG00000116266(STXBP3)	--	10.5084	441	11.638	487	10.7812	443	11.1942	474	11.5978	483	10.4761	439	0.96842125	0.0730307	normal	0.970248267	-0.033221552	normal	0.970441914	-0.021304143	normal	0.995199929	0.004580951	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	"K15301|0|hsa:6814|STXBP3, MUNC18-3, MUNC18C, PSP, UNC-18C; syntaxin binding protein 3; K15301 syntaxin-binding protein 3 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec1 family	Syntaxin-binding protein 3 GN=STXBP3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-binding protein 3 [Oryctolagus cuniculus]
ENSG00000116273(PHF13)	--	10.22762295	623	9.239925	559	8.884895081	552	6.982583629	425	8.375672391	511	7.124306811	435	0.136355922	-0.580855518	normal	0.960077941	-0.150525448	normal	0.830143852	-0.350858831	normal	0.073893105	-0.360002339	normal	--	--	--	--	--	[R]	General function prediction only	PHD-finger	PHD finger protein 13 GN=PHF13 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: PHD finger protein 13 [Orcinus orca] 
ENSG00000116285(ERRFI1)	--	61.94284445	3377	75.97651676	4111	56.42909388	3047	34.71036257	1871	29.22094373	1572	49.36372746	2684	1.63E-05	-0.882217212	normal	4.66E-15	-1.407443865	down	0.978943127	-0.191195089	normal	0.006938149	-0.802477122	normal	--	--	--	--	--	--	--	GTPase binding;; EGFR receptor inhibitor Mig-6	ERBB receptor feedback inhibitor 1 GN=ERRFI1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ERBB receptor feedback inhibitor 1 [Galeopterus variegatus]
ENSG00000116288(PARK7)	--	185.2215917	2833	193.2585911	2984	189.3696609	2916	194.131465	3018	178.9292356	2701	182.7759174	2783	0.989285589	0.060398203	normal	0.982210316	-0.165092465	normal	0.988604747	-0.075601115	normal	0.812661443	-0.06015436	normal	[R]	General function prediction only	--	K05687|1.09849e-133|nle:100590226|PARK7; parkinson protein 7; K05687 protein DJ-1 (A)	Parkinson's disease (ko05012)	[RV]	General function prediction only;; Defense mechanisms	DJ-1/PfpI family;; Putative amidotransferase	Protein DJ-1 (Precursor) GN=PARK7 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: protein DJ-1 isoform X1 [Tupaia chinensis] 
ENSG00000116299(KIAA1324)	--	0.121468655	7	0.189431782	12	0.335176911	16	0.239021042	15	0.315106517	19	0.551883374	35	--	--	--	--	--	--	0.784878881	1.052252773	normal	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	--	UPF0577 protein KIAA1324 (Precursor) GN=KIAA1324 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: UPF0577 protein KIAA1324 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000116329(OPRD1)	--	0.00557821	1	0.005432512	1	0	0	0	0	0.032713609	5	0.005550778	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04213|0|ggo:101129708|OPRD1; delta-type opioid receptor; K04213 delta-type opioid receptor (A)	cGMP-PKG signaling pathway (ko04022);; Sphingolipid signaling pathway (ko04071);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srx	Delta-type opioid receptor GN=OPRD1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: delta-type opioid receptor [Odobenus rosmarus divergens]
ENSG00000116350(SRSF4)	--	18.35044915	984	17.62261735	911	19.49687446	1061	18.77943679	978	22.82517801	1221	17.98775945	940	0.978739229	-0.039594101	normal	0.731677953	0.400537523	normal	0.963034968	-0.182706579	normal	0.818183815	0.065709556	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12893|4.85848e-97|mmu:57317|Srsf4, 5730499P16Rik, AW550192, MNCb-2616, SRp75, Sfrs4; serine/arginine-rich splicing factor 4; K12893 splicing factor, arginine/serine-rich 4/5/6 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Serine/arginine-rich splicing factor 4 GN=SRSF4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 4 isoform 3 [Dasypus novemcinctus]
ENSG00000116353(MECR)	--	10.052012	276	8.83524287	253	7.0827377	206	10.206678	295	10.535266	298	8.675157	243	0.965770349	0.064865135	normal	0.941213777	0.21357107	normal	0.939839902	0.228474612	normal	0.626557214	0.1636481	normal	[CR]	Energy production and conversion;; General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	K07512|0|ptr:456690|MECR; mitochondrial trans-2-enoyl-CoA reductase; K07512 mitochondrial trans-2-enoyl-CoA reductase [EC:1.3.1.38] (A)	Fatty acid elongation (ko00062);; Fatty acid metabolism (ko01212)	[KC]	Transcription;; Energy production and conversion	Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	"Trans-2-enoyl-CoA reductase, mitochondrial (Precursor) GN=MECR OS=Homo sapiens (Human) PE=1 SV=2"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: trans-2-enoyl-CoA reductase, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000116396(KCNC4)	--	3.649123996	395	2.642564797	334	3.148185467	327	2.162488804	244	1.762891538	223	1.639386534	161	0.023777634	-0.722192279	normal	0.221847531	-0.600877301	normal	0.000100703	-1.023632304	down	0.000378873	-0.772275449	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04890|0|ptr:457122|KCNC4; potassium voltage-gated channel, Shaw-related subfamily, member 4; K04890 potassium voltage-gated channel Shaw-related subfamily C member 4 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Potassium voltage-gated channel;; Ion channel	Potassium voltage-gated channel subfamily C member 4 GN=KCNC4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily C member 4 isoform X3 [Galeopterus variegatus]
ENSG00000116406(EDEM3)	--	7.247676092	804	8.710619367	968	8.67499692	943	10.65364684	1188	10.30461429	1138	11.84784129	1311	0.217584969	0.531594738	normal	0.955634038	0.211689763	normal	0.475546684	0.466409431	normal	0.012531526	0.400951049	normal	--	--	"Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: membrane (GO:0016020);; "	"K10086|0|hsa:80267|EDEM3, C1orf22; ER degradation enhancer, mannosidase alpha-like 3 (EC:3.2.1.113); K10086 ER degradation enhancer, mannosidase alpha-like 3 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 47;; PA domain	ER degradation-enhancing alpha-mannosidase-like protein 3 (Precursor) GN=EDEM3 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: ER degradation-enhancing alpha-mannosidase-like protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000116455(WDR77)	--	18.74535423	780	19.88325984	823	20.23339	839	23.14843	967	19.68431	799	17.246528	730	0.91671044	0.278715671	normal	0.974918393	-0.064004116	normal	0.951357612	-0.208662224	normal	0.980122653	0.009541249	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K13221|0|hsa:79084|WDR77, MEP-50, MEP50, Nbla10071, p44, p44/Mep50; WD repeat domain 77; K13221 methylosome protein 50 (A)"	--	[A]	RNA processing and modification	"WD domain, G-beta repeat"	Methylosome protein 50 GN=WDR77 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: methylosome protein 50 [Tupaia chinensis]
ENSG00000116459(ATP5F1)	--	53.4018282	1540	56.17795167	1475	62.99980258	1555	74.169955	2099	60.83715088	1804	62.85934666	1807	0.702797946	0.415583188	normal	0.94205613	0.268808264	normal	0.966193237	0.208202487	normal	0.066518832	0.299668957	normal	--	--	"Cellular Component: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) (GO:0000276);; Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP synthesis coupled proton transport (GO:0015986);; "	"K02127|8.63875e-179|ggo:101153285|ATP5F1; ATP synthase subunit b, mitochondrial; K02127 F-type H+-transporting ATPase subunit b (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Mitochondrial ATP synthase B chain precursor (ATP-synt_B)	"ATP synthase F(0) complex subunit B1, mitochondrial (Precursor) GN=ATP5F1 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: ATP synthase F(0) complex subunit B1, mitochondrial [Pteropus alecto] "
ENSG00000116473(RAP1A)	--	20.3944513	538	24.42752068	582	18.78429067	500	26.87300089	714	23.75812236	621	20.8971238	533	0.777219277	0.376549551	normal	0.970768929	0.071966511	normal	0.968952785	0.083670853	normal	0.431907814	0.183209672	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K04353|7.64348e-115|myd:102774675|RAP1A; RAP1A, member of RAS oncogene family; K04353 Ras-related protein Rap-1A (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Pancreatic secretion (ko04972);; Renal cell carcinoma (ko05211)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	Ras-related protein Rap-1A (Precursor) GN=RAP1A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Rap-1A isoform X1 [Myotis brandtii] 
ENSG00000116478(HDAC1)	--	39.45400314	1664	38.87540324	1656	38.27660421	1631	41.3897333	1756	42.36245538	1768	34.56784057	1451	0.98474317	0.046763115	normal	0.983450261	0.072924587	normal	0.971689776	-0.176826768	normal	0.966740066	-0.014751115	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	--	--	[B]	Chromatin structure and dynamics	Histone deacetylase domain	Histone deacetylase 1 GN=HDAC1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 1 [Ochotona princeps]
ENSG00000116489(CAPZA1)	--	47.7848	2377	47.173178	2343	46.1809	2269	65.159715	3269	59.92461	2980	51.072037	2552	0.699498834	0.428638091	normal	0.918436124	0.325342228	normal	0.980768458	0.161178931	normal	0.053042439	0.310594822	normal	--	--	Cellular Component: F-actin capping protein complex (GO:0008290);; Biological Process: barbed-end actin filament capping (GO:0051016);; 	"K10364|0|ptr:457101|CAPZA1; capping protein (actin filament) muscle Z-line, alpha 1; K10364 capping protein (actin filament) muscle Z-line, alpha (A)"	--	[Z]	Cytoskeleton	F-actin capping protein alpha subunit	F-actin-capping protein subunit alpha-1 GN=CAPZA1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	F-actin-capping protein subunit alpha-1 [Bos taurus] 
ENSG00000116497(S100PBP)	--	9.305742042	565	12.32694301	699	9.812022621	612	9.428784294	530	9.965624	582	9.6651762	592	0.965312799	-0.122746042	normal	0.906971102	-0.285022984	normal	0.972423389	-0.056085	normal	0.511245375	-0.159669386	normal	--	--	Molecular Function: calcium-dependent protein binding (GO:0048306);; 	--	--	--	--	S100P-binding protein	S100P-binding protein OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: S100P-binding protein [Felis catus] 
ENSG00000116514(RNF19B)	--	7.578886931	343	9.702825055	477	8.479004126	406	8.325272176	377	8.437616605	366	12.12871834	559	0.963685283	0.105074651	normal	0.743034898	-0.4021121	normal	0.581131124	0.451637566	normal	0.910106219	0.066663475	normal	--	--	--	K11973|0|mcf:101926204|uncharacterized LOC101926204; K11973 E3 ubiquitin-protein ligase RNF19B [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain	E3 ubiquitin-protein ligase RNF19B GN=RNF19B OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF19B [Ceratotherium simum simum]
ENSG00000116521(SCAMP3)	--	78.1008	1709	74.0048	1647	72.5788	1632	60.3374	1335	56.3955	1225	75.0979	1663	0.775557014	-0.386750352	normal	0.581960796	-0.448006473	normal	0.984929892	0.018838376	normal	0.1434328	-0.260804512	normal	--	--	Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SCAMP family	Secretory carrier-associated membrane protein 3 GN=SCAMP3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: secretory carrier-associated membrane protein 3 [Balaenoptera acutorostrata scammoni]
ENSG00000116525(TRIM62)	--	2.295198755	154	1.456204886	103	1.927727377	135	1.740845146	121	1.7339446	123	1.317769683	92	0.890829849	-0.37452837	normal	0.951580313	0.231474127	normal	0.710644074	-0.553981428	normal	0.591874223	-0.244124056	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: intracellular (GO:0005622);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; Molecular Function: metal ion binding (GO:0046872);; 	"K12030|0|hsa:55223|TRIM62, DEAR1; tripartite motif containing 62; K12030 tripartite motif-containing protein 62 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; B-box zinc finger"	E3 ubiquitin-protein ligase TRIM62 GN=TRIM62 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM62 [Pteropus alecto] 
ENSG00000116539(ASH1L)	--	9.297079001	2188	10.32650974	2414	10.00129	2323	9.410502806	2216	9.859502001	2297	9.806786862	2321	0.987705366	-0.012478414	normal	0.985826629	-0.093041615	normal	0.988183111	-0.009527868	normal	0.883153791	-0.040124827	normal	[R]	General function prediction only	Molecular Function: chromatin binding (GO:0003682);; Molecular Function: protein binding (GO:0005515);; 	"K06101|0|hsa:55870|ASH1L, ASH1, ASH1L1, KMT2H; ash1 (absent, small, or homeotic)-like (Drosophila) (EC:2.1.1.43); K06101 histone-lysine N-methyltransferase ASH1L [EC:2.1.1.43] (A)"	Lysine degradation (ko00310);; Tight junction (ko04530)	[K]	Transcription	SET domain;; BAH domain;; Bromodomain;; PHD-finger	Histone-lysine N-methyltransferase ASH1L GN=ASH1L OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: histone-lysine N-methyltransferase ASH1L isoform X1 [Equus caballus]
ENSG00000116544(DLGAP3)	--	0.087808478	6	0.079650294	6	0.041555637	2	0.029106776	2	0.04231529	2	0.043066378	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signaling (GO:0023052);; 	--	--	[T]	Signal transduction mechanisms	Guanylate-kinase-associated protein (GKAP) protein	Disks large-associated protein 3 GN=DLGAP3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	disks large-associated protein 3 [Bos taurus] 
ENSG00000116560(SFPQ)	--	84.48384	6366	88.041575	6600	86.28884976	6444	102.14098	7887	121.9045	8937	89.371242	6881	0.975230453	0.278196808	normal	0.858690371	0.415815882	normal	0.99387563	0.086350694	normal	0.141751304	0.266897103	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13219|0|nle:100596017|SFPQ; splicing factor proline/glutamine-rich; K13219 splicing factor, proline- and glutamine-rich (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; NOPS (NUC059) domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"Splicing factor, proline- and glutamine-rich GN=SFPQ OS=Homo sapiens (Human) PE=1 SV=2"	A	RNA processing and modification	"PREDICTED: splicing factor, proline- and glutamine-rich [Orycteropus afer afer]"
ENSG00000116574(RHOU)	--	2.955747606	251	2.021475618	172	2.813545	230	4.473288	349	4.891081	378	2.78293676	222	0.682494447	0.442401884	normal	8.49E-06	1.107818259	up	0.965653293	-0.058970933	normal	0.20804703	0.517287234	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07865|1.03576e-155|mcf:102124631|RHOU; ras homolog family member U; K07865 Ras homolog gene family, member U (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoU OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoU-like [Canis lupus familiaris]
ENSG00000116580(GON4L)	--	5.23765627	1079	5.655019552	1139	5.89504	1168	6.348143046	1413	6.123891286	1360	6.255135566	1401	0.829790667	0.357788005	normal	0.951279924	0.234127559	normal	0.942730163	0.25382478	normal	0.100879778	0.280703287	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	Paired amphipathic helix repeat;; Myb-like DNA-binding domain	GON-4-like protein GN=GON4L OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GON-4-like protein [Galeopterus variegatus]
ENSG00000116584(ARHGEF2)	--	7.700475321	671	7.711143443	627	8.407783694	680	7.541656545	571	7.01835264	613	7.695533202	615	0.921499036	-0.263000581	normal	0.972163789	-0.053873507	normal	0.962715028	-0.152882093	normal	0.510176555	-0.15769288	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K12791|0|mcf:102131561|ARHGEF2; Rho/Rac guanine nucleotide exchange factor (GEF) 2; K12791 Rho guanine nucleotide exchange factor 2 (A)	--	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain	Rho guanine nucleotide exchange factor 2 GN=ARHGEF2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 2 [Galeopterus variegatus]
ENSG00000116586(LAMTOR2)	--	74.356881	602	73.89457075	612	74.86119197	637	90.99694514	770	88.90081092	716	86.62727146	716	0.867224421	0.323531078	normal	0.949625129	0.204533728	normal	0.961921603	0.160016269	normal	0.271136083	0.229165499	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Roadblock/LC7 domain	Ragulator complex protein LAMTOR2 GN=LAMTOR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ragulator complex protein LAMTOR2 isoform X2 [Mustela putorius furo] 
ENSG00000116604(MEF2D)	--	19.61042358	1865	21.8822221	2193	21.5299734	1971	14.26669298	1477	15.41226096	1535	18.87202302	2027	0.827114895	-0.36699742	normal	0.227009217	-0.535649674	normal	0.986615664	0.032102581	normal	0.225872365	-0.279115827	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein dimerization activity (GO:0046983);; 	K09262|0|ptr:457396|MEF2D; myocyte enhancer factor 2D; K09262 MADS-box transcription enhancer factor 2D (A)	cGMP-PKG signaling pathway (ko04022)	[K]	Transcription	SRF-type transcription factor (DNA-binding and dimerisation domain);; Holliday junction regulator protein family C-terminal repeat	Myocyte-specific enhancer factor 2D GN=MEF2D OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myocyte-specific enhancer factor 2D [Condylura cristata]
ENSG00000116641(DOCK7)	--	8.236213387	971	8.847909906	999	10.57253754	1079	8.810777261	1025	6.9468393	773	7.801738001	858	0.978684167	0.04717579	normal	0.752165347	-0.390768299	normal	0.854112343	-0.338403654	normal	0.249698436	-0.220777069	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Dedicator of cytokinesis;; C2 domain in Dock180 and Zizimin proteins;; Domain of unknown function (DUF3398)	Dedicator of cytokinesis protein 7 GN=DOCK7 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 7 isoform X2 [Physeter catodon]
ENSG00000116649(SRM)	--	60.0986205	1270	67.133271	1437	65.626042	1418	75.63796104	1616	68.7411419	1436	57.19895355	1221	0.897538897	0.316426404	normal	0.98304185	-0.022407281	normal	0.956341363	-0.223828268	normal	0.916393929	0.02888759	normal	[E]	Amino acid transport and metabolism	--	"K00797|0|hsa:6723|SRM, PAPT, SPDSY, SPS1, SRML1; spermidine synthase (EC:2.5.1.16); K00797 spermidine synthase [EC:2.5.1.16] (A)"	Cysteine and methionine metabolism (ko00270);; Arginine and proline metabolism (ko00330);; beta-Alanine metabolism (ko00410);; Glutathione metabolism (ko00480)	[E]	Amino acid transport and metabolism	Spermine/spermidine synthase	Spermidine synthase GN=SRM OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: spermidine synthase [Orycteropus afer afer]
ENSG00000116661(FBXO2)	--	21.09960001	547	14.234	394	13.47509107	374	3.36639	89	7.06997	183	3.888600005	102	0	-2.629543941	down	4.16E-06	-1.121303401	down	1.33E-15	-1.867272251	down	9.41E-07	-1.834790093	down	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10099|3.93888e-154|hsa:26232|FBXO2, FBG1, FBX2, Fbs1, NFB42, OCP1; F-box protein 2; K10099 F-box protein 2 (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	--	--	F-box associated region;; F-box-like;; F-box domain	F-box only protein 2 GN=FBXO2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: F-box only protein 2 [Tupaia chinensis]
ENSG00000116663(FBXO6)	--	4.4837886	114	4.776423537	124	4.609086037	117	3.395177	88	3.458672155	88	3.421930683	89	0.905702898	-0.398163671	normal	0.799462817	-0.508787442	normal	0.904105199	-0.397020353	normal	0.282646497	-0.443027443	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10100|0|pps:100978939|FBXO6; F-box protein 6; K10100 F-box protein 6 (A)	Protein processing in endoplasmic reticulum (ko04141)	--	--	F-box associated region;; F-box-like;; F-box domain	F-box only protein 6 GN=FBXO6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box only protein 6 [Odobenus rosmarus divergens]
ENSG00000116667(C1orf21)	--	2.853253	542	1.842776	350	2.277533	427	0.67404	127	0.8451318	159	0.9001777	171	0	-2.110803424	down	3.99E-06	-1.152170901	down	7.15E-09	-1.320877914	down	2.11E-06	-1.549433803	down	--	--	--	--	--	--	--	Domain of unknown function (DUF4612)	Uncharacterized protein C1orf21 GN=C1orf21 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	uncharacterized protein C1orf21 homolog [Bos taurus] 
ENSG00000116668(SWT1)	--	2.154677504	131	2.2312089	128	1.859082043	108	1.806219675	106	2.181716144	111	1.90735396	132	0.924301763	-0.331996657	normal	0.951485971	-0.224163878	normal	0.941446573	0.277692534	normal	0.874611439	-0.093398413	normal	--	--	--	--	--	[A]	RNA processing and modification	PIN domain	Transcriptional protein SWT1 GN=SWT1 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: transcriptional protein SWT1 [Ceratotherium simum simum]
ENSG00000116670(MAD2L2)	--	25.77228829	502	19.56119224	394	22.55913949	462	23.52778861	468	25.67863069	502	18.13352988	358	0.962761937	-0.131593832	normal	0.865650208	0.326951049	normal	0.796757733	-0.37482698	normal	0.890188833	-0.053966839	normal	--	--	--	K13728|3.5966e-149|ptr:457953|MAD2L2; MAD2 mitotic arrest deficient-like 2 (yeast); K13728 mitotic spindle assembly checkpoint protein MAD2B (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914);; Bacterial invasion of epithelial cells (ko05100)	[D]	"Cell cycle control, cell division, chromosome partitioning"	HORMA domain	Mitotic spindle assembly checkpoint protein MAD2B GN=MAD2L2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	hypothetical protein PANDA_011814 [Ailuropoda melanoleuca]
ENSG00000116675(DNAJC6)	--	1.804785933	159	1.782766453	152	1.679550829	171	2.462026856	222	1.908600535	189	1.527086824	144	0.76155854	0.447030361	normal	0.922211876	0.29029393	normal	0.939470525	-0.253770153	normal	0.65663355	0.181179165	normal	--	--	--	"K09526|0|hsa:9829|DNAJC6, DJC6, PARK19; DnaJ (Hsp40) homolog, subfamily C, member 6 (EC:3.1.3.48); K09526 DnaJ homolog subfamily C member 6 (A)"	Endocytosis (ko04144)	[TR]	Signal transduction mechanisms;; General function prediction only	C2 domain of PTEN tumour-suppressor protein;; DnaJ domain	Putative tyrosine-protein phosphatase auxilin GN=DNAJC6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: putative tyrosine-protein phosphatase auxilin isoform X1 [Tupaia chinensis]
ENSG00000116678(LEPR)	--	24.52566509	1612	26.69815404	1724	24.67698462	1572	28.69438653	1893	24.66714002	1601	29.2747449	1913	0.968760416	0.200813642	normal	0.979268289	-0.128096387	normal	0.939661357	0.274704292	normal	0.579236144	0.118339672	normal	--	--	--	K05062|0|pps:100975260|LEPR; leptin receptor; K05062 leptin receptor (A)	Cytokine-cytokine receptor interaction (ko04060);; Neuroactive ligand-receptor interaction (ko04080);; AMPK signaling pathway (ko04152);; Jak-STAT signaling pathway (ko04630);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	--	--	Ig-like C2-type domain;; Fibronectin type III domain	Leptin receptor (Precursor) GN=LEPR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leptin receptor-like isoform 1 [Ceratotherium simum simum]
ENSG00000116679(IVNS1ABP)	--	22.313485	1500	20.0802298	1408	25.789249	1697	28.446132	1966	30.609772	2103	31.841509	2188	0.8447211	0.359146408	normal	0.158929813	0.556882512	normal	0.853987457	0.358053003	normal	0.005104041	0.421712694	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K15046|0|pps:100989344|IVNS1ABP; influenza virus NS1A binding protein; K15046 influenza virus NS1A-binding protein (A)	Influenza A (ko05164)	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; BTB/POZ domain;; Kelch motif;; BTB And C-terminal Kelch"	Influenza virus NS1A-binding protein GN=HSPC068 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: influenza virus NS1A-binding protein isoform X1 [Tupaia chinensis]
ENSG00000116685(KIAA2013)	--	26.4904161	1251	24.88182014	1221	26.41513983	1294	23.68686306	1134	27.34147117	1279	21.823019	1059	0.968200194	-0.172271063	normal	0.98096366	0.045471478	normal	0.910057347	-0.297042053	normal	0.513298746	-0.138482451	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2152)	Uncharacterized protein KIAA2013 (Precursor) GN=KIAA2013 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA2013 homolog [Odobenus rosmarus divergens]
ENSG00000116688(MFN2)	--	19.199019	1802	19.751103	1875	20.089352	1699	22.102847	2029	20.8605519	1920	19.720953	1837	0.980145387	0.140224876	normal	0.985990369	0.012778972	normal	0.98238187	0.104285043	normal	0.715334529	0.084393193	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: lipid transport (GO:0006869);; Biological Process: mitochondrial fusion (GO:0008053);; Molecular Function: lipid binding (GO:0008289);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K06030|0|hsa:9927|MFN2, CMT2A, CMT2A2, CPRP1, HSG, MARF; mitofusin 2; K06030 mitofusin [EC:3.6.5.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	fzo-like conserved region;; Dynamin family;; 50S ribosome-binding GTPase	Mitofusin-2 GN=MFN2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitofusin-2 isoform X1 [Tupaia chinensis]
ENSG00000116690(PRG4)	--	0.060104138	7	0.12431924	14	0.035208804	3	0.124010003	14	0.404635	48	0.398273167	49	--	--	--	0.021785477	1.654320405	normal	9.22E-08	3.477925931	up	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: immune response (GO:0006955);; Molecular Function: polysaccharide binding (GO:0030247);; 	--	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Somatomedin B domain;; Hemopexin	Proteoglycan 4 C-terminal part (Precursor) GN=PRG4 OS=Homo sapiens (Human) PE=1 SV=2	OW	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	PREDICTED: LOW QUALITY PROTEIN: proteoglycan 4 [Orcinus orca]
ENSG00000116691(MIIP)	--	7.04415	227	6.88834	225	6.168973	203	6.37314	213	5.265	172	5.496182	181	0.960802103	-0.121819707	normal	0.817833875	-0.405813137	normal	0.954572026	-0.172420364	normal	0.510666523	-0.232648331	normal	--	--	Biological Process: negative regulation of G2/M transition of mitotic cell cycle (GO:0010972);; Biological Process: negative regulation of cell migration (GO:0030336);; 	--	--	--	--	--	Migration and invasion-inhibitory protein GN=MIIP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: migration and invasion-inhibitory protein [Camelus ferus]
ENSG00000116698(SMG7)	--	15.36896074	1770	16.38303925	1822	17.30355155	1941	16.0238584	1807	14.29731996	1608	14.57325	1675	0.985818208	-0.000984272	normal	0.968175878	-0.201503937	normal	0.964133508	-0.220745142	normal	0.487926017	-0.141722809	normal	--	--	--	"K14409|0|mcc:717603|SMG7; smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans); K14409 protein SMG7 (A)"	mRNA surveillance pathway (ko03015)	--	--	Est1 DNA/RNA binding domain;; Telomerase activating protein Est1;; TPR repeat	Protein SMG7 GN=SMG7 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: protein SMG7 isoform 1 [Ceratotherium simum simum]
ENSG00000116701(NCF2)	--	0.767266044	12	3.665337758	31	1.177812272	7	7.421338677	143	9.178701549	178	3.095620572	66	0	3.387591568	up	5.77E-15	2.444187622	up	1.10E-08	2.980069288	up	0.000798535	2.927812791	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08010|0|hsa:4688|NCF2, NCF-2, NOXA2, P67-PHOX, P67PHOX; neutrophil cytosolic factor 2; K08010 neutrophil cytosolic factor 2 (A)"	Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Leukocyte transendothelial migration (ko04670);; Leishmaniasis (ko05140)	[T]	Signal transduction mechanisms	SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; PB1 domain;; Tetratricopeptide repeat	Neutrophil cytosol factor 2 GN=NCF2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neutrophil cytosol factor 2 isoform X1 [Galeopterus variegatus]
ENSG00000116703(PDC)	--	0.055872355	1	0.055030985	1	0.054932208	0	0.109012483	2	0.054340326	0	0.054874811	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08327|0|hsa:5132|PDC, MEKA, PHD, PhLOP, PhLP; phosducin; K08327 phosducin (A)"	Olfactory transduction (ko04740)	[T]	Signal transduction mechanisms	Phosducin	Phosducin GN=PDC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosducin [Pteropus alecto] 
ENSG00000116704(SLC35D1)	--	4.314975802	391	5.243027	477	4.03082619	361	4.300290809	391	4.342929325	392	5.354648769	485	0.969094076	-0.030711583	normal	0.889552044	-0.303498814	normal	0.703484627	0.416185084	normal	0.958415001	0.024147588	normal	--	--	--	"K15281|0|ptr:745548|SLC35D1; solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1; K15281 solute carrier family 35 (A)"	--	[GOU]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Triose-phosphate Transporter family	UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter GN=SLC35D1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter [Orycteropus afer afer]
ENSG00000116711(PLA2G4A)	--	12.1505	628	13.1962	678	11.2487	568	10.8601	563	21.3345	1093	19.2601	991	0.953394399	-0.187975854	normal	0.019794124	0.666328692	normal	0.000800453	0.793083876	normal	0.329392599	0.478451839	normal	--	--	Molecular Function: phospholipase activity (GO:0004620);; Biological Process: phospholipid catabolic process (GO:0009395);; 	"K16342|0|ptr:469617|PLA2G4A; phospholipase A2, group IVA (cytosolic, calcium-dependent); K16342 cytosolic phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Platelet activation (ko04611);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Oxytocin signaling pathway (ko04921);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Lysophospholipase catalytic domain;; C2 domain	Lysophospholipase GN=PLA2G4A OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: cytosolic phospholipase A2-like [Tupaia chinensis]
ENSG00000116717(GADD45A)	--	17.44539804	438	18.26936181	485	20.69715095	562	29.81191108	773	23.79823497	600	20.04793819	523	0.001477395	0.786602487	normal	0.905378423	0.284751642	normal	0.966724002	-0.111738862	normal	0.271951086	0.33040791	normal	--	--	--	"K04402|8.40842e-118|pps:100990548|GADD45A; growth arrest and DNA-damage-inducible, alpha; K04402 growth arrest and DNA-damage-inducible protein (A)"	MAPK signaling pathway (ko04010);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115)	--	--	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	Growth arrest and DNA damage-inducible protein GADD45 alpha GN=GADD45A OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	growth arrest and DNA damage-inducible protein GADD45 alpha [Bos taurus] 
ENSG00000116729(WLS)	--	15.22674136	727	14.17119082	662	14.87960379	651	21.47558095	975	19.19808855	905	25.32050404	1188	0.739193464	0.391897228	normal	0.639536278	0.428819123	normal	9.76E-05	0.858016636	normal	0.002176224	0.568000745	normal	--	--	--	--	--	--	--	Wnt-binding factor required for Wnt secretion	Protein wntless homolog (Precursor) GN=WLS OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein wntless homolog isoformX1 [Sus scrofa]
ENSG00000116731(PRDM2)	--	5.051174734	586	6.117672767	655	4.427345838	542	4.775326043	533	4.367779363	548	4.46240878	566	0.957804466	-0.167137661	normal	0.911427511	-0.278042668	normal	0.971606905	0.054070118	normal	0.598083532	-0.135729139	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11432|0|pon:100436958|PRDM2; PR domain containing 2, with ZNF domain; K11432 PR domain zinc finger protein 2 (A)"	--	[K]	Transcription	"C2H2-type zinc finger;; Zinc finger, C2H2 type;; Zinc-finger double-stranded RNA-binding;; SET domain"	PR domain zinc finger protein 2 GN=PRDM2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: PR domain zinc finger protein 2 isoform 1 [Dasypus novemcinctus] 
ENSG00000116741(RGS2)	--	6.34667	162	4.41084	112	6.09248	154	13.5527	349	15.5008	394	11.2204	288	2.72E-05	1.069332246	up	2.31E-14	1.779631156	up	0.003082751	0.888366528	normal	4.90E-08	1.247030823	up	--	--	--	K18154|3.91591e-141|pps:100995309|RGS2; regulator of G-protein signaling 2; K18154 regulator of G-protein signaling 2 (A)	cGMP-PKG signaling pathway (ko04022);; Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 2 GN=RGS2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 2 [Ceratotherium simum simum]
ENSG00000116747(TROVE2)	--	15.622554	1305	15.093921	1432	14.92908753	1413	15.87294418	1559	16.69816395	1458	13.70899201	1402	0.957388649	0.225495719	normal	0.983253427	0.00452793	normal	0.983292409	-0.019545557	normal	0.77952704	0.069129012	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K11089|0|ptr:745289|TROVE2; TROVE domain family, member 2; K11089 60 kDa SS-A/Ro ribonucleoprotein (A)"	Systemic lupus erythematosus (ko05322)	[S]	Function unknown	TROVE domain;; VWA-like domain (DUF2201)	60 kDa SS-A/Ro ribonucleoprotein GN=TROVE2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: 60 kDa SS-A/Ro ribonucleoprotein isoform X2 [Canis lupus familiaris]
ENSG00000116750(UCHL5)	--	28.83360346	1027	29.98134271	1050	33.82615044	1084	33.53929318	1192	34.04131555	1157	23.36790465	843	0.964407398	0.183860308	normal	0.974660365	0.118410471	normal	0.794731611	-0.37046398	normal	0.986622528	-0.00796954	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Cellular Component: intracellular (GO:0005622);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; 	K05610|0|ptr:457596|UCHL5; ubiquitin carboxyl-terminal hydrolase L5; K05610 ubiquitin carboxyl-terminal hydrolase L5 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ubiquitin carboxyl-terminal hydrolase, family 1"	Ubiquitin carboxyl-terminal hydrolase isozyme L5 GN=UCHL5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	hypothetical protein PANDA_012567 [Ailuropoda melanoleuca]
ENSG00000116752(BCAS2)	--	14.561358	300	17.060702	354	16.031388	330	17.12355	358	16.83933914	359	16.09444779	343	0.93825191	0.223117775	normal	0.967974868	-0.001187039	normal	0.967554828	0.047238763	normal	0.809912672	0.086013542	normal	--	--	Biological Process: mRNA processing (GO:0006397);; 	K12861|1.69286e-158|ptr:457143|BCAS2; breast carcinoma amplified sequence 2; K12861 pre-mRNA-splicing factor SPF27 (A)	Spliceosome (ko03040)	[S]	Function unknown	Breast carcinoma amplified sequence 2 (BCAS2)	Pre-mRNA-splicing factor SPF27 GN=BCAS2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pre-mRNA-splicing factor SPF27 [Pteropus alecto] 
ENSG00000116754(SRSF11)	--	32.203175	1726	36.95746817	1852	33.63109626	1807	39.28194926	1951	39.42150067	1978	35.35670488	1829	0.978962999	0.145826905	normal	0.984623635	0.073473711	normal	0.985972653	0.009159507	normal	0.751607741	0.075268677	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12899|4.44801e-99|ptr:456937|SRSF11, SFRS11; serine/arginine-rich splicing factor 11; K12899 splicing factor, arginine/serine-rich 11 (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Serine/arginine-rich splicing factor 11 GN=SRSF11 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"PREDICTED: serine/arginine-rich splicing factor 11-like, partial [Tursiops truncatus]"
ENSG00000116761(CTH)	--	1.811620362	50	0.935598065	25	1.670111629	43	1.410065063	38	1.003676422	31	1.739712606	56	0.960147566	-0.412183213	normal	0.980833863	0.27400677	normal	0.961277724	0.361624991	normal	0.959389613	0.063468792	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	K01758|0|pps:100968341|CTH; cystathionine gamma-lyase; K01758 cystathionine gamma-lyase [EC:4.4.1.1] (A)	"Glycine, serine and threonine metabolism (ko00260);; Cysteine and methionine metabolism (ko00270);; Selenocompound metabolism (ko00450);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Cys/Met metabolism PLP-dependent enzyme;; Aminotransferase class I and II;; Aminotransferase class-V;; DegT/DnrJ/EryC1/StrS aminotransferase family	Cystathionine gamma-lyase GN=CTH OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: cystathionine gamma-lyase [Tupaia chinensis]
ENSG00000116771(AGMAT)	--	3.29882	134	3.283	135	3.2936	135	4.6002	189	4.79497	195	4.25163	174	0.773077919	0.46085284	normal	0.683581238	0.50436327	normal	0.894764486	0.354331425	normal	0.175766349	0.444520041	normal	[E]	Amino acid transport and metabolism	Molecular Function: metal ion binding (GO:0046872);; 	K01480|0|hsa:79814|AGMAT; agmatine ureohydrolase (agmatinase) (EC:3.5.3.11); K01480 agmatinase [EC:3.5.3.11] (A)	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	Arginase family	"Agmatinase, mitochondrial (Precursor) GN=AGMAT OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: agmatinase, mitochondrial [Tupaia chinensis]"
ENSG00000116774(OLFML3)	--	0.175733683	6	0.171287227	6	0.368091594	12	4.757342458	164	5.534322596	188	5.560894334	191	0	4.42957159	up	0	4.637711996	up	0	3.824811773	up	2.55E-31	4.480488739	up	--	--	--	--	--	[W]	Extracellular structures	Olfactomedin-like domain	Olfactomedin-like protein 3 (Precursor) GN=OLFML3 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: olfactomedin-like protein 3 [Orcinus orca] 
ENSG00000116783(TNNI3K)	--	10.71178201	384	7.675930821	342	8.40880967	330	6.802562698	259	6.543170107	259	7.345022651	278	0.185253741	-0.596061904	normal	0.737600256	-0.420327485	normal	0.925948771	-0.254400738	normal	0.072157262	-0.428895827	normal	[R]	General function prediction only	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17535|0|hsa:51086|TNNI3K, CARK, CCDD; TNNI3 interacting kinase (EC:2.7.11.1); K17535 serine/threonine-protein kinase TNNI3K [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Protein tyrosine kinase;; Ankyrin repeats (many copies);; Protein kinase domain;; Ankyrin repeat;; Ankyrin repeats (many copies)	Serine/threonine-protein kinase TNNI3K OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase TNNI3K [Pteropus alecto]
ENSG00000116785(CFHR3)	--	0.948842164	29	0.829361092	31	0.873743002	20	0.74982666	20	0.2626225	9	0.688802773	19	0.972504563	-0.532708331	normal	0.238528181	-1.648295986	normal	0.9888544	-0.07636691	normal	0.28860683	-0.759354524	normal	--	--	--	--	--	--	--	Sushi domain (SCR repeat)	Complement factor H-related protein 3 (Precursor) GN=CFHR3 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: complement factor H-related protein 3-like [Myotis brandtii]
ENSG00000116786(PLEKHM2)	--	13.11366	1173	14.02319	1267	13.88846	1266	15.10238	1337	14.43747	1276	17.49389	1559	0.971635511	0.157770533	normal	0.981815307	-0.011201431	normal	0.920717997	0.291737506	normal	0.466177253	0.150168529	normal	--	--	--	"K15348|0|hsa:23207|PLEKHM2, SKIP; pleckstrin homology domain containing, family M (with RUN domain) member 2; K15348 pleckstrin homology domain-containing family M member 2 (A)"	Salmonella infection (ko05132)	--	--	RUN domain;; PH domain	Pleckstrin homology domain-containing family M member 2 GN=PLEKHM2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family M member 2 [Ceratotherium simum simum]
ENSG00000116791(CRYZ)	--	53.817393	1313	52.03520809	1217	57.84806848	1387	75.5308789	1792	65.602871	1558	66.98832383	1620	0.684411476	0.417451871	normal	0.877189015	0.334571247	normal	0.961856866	0.215516952	normal	0.046531986	0.322133076	normal	[CR]	Energy production and conversion;; General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	"K00344|0|hsa:1429|CRYZ; crystallin, zeta (quinone reductase) (EC:1.6.5.5); K00344 NADPH2:quinone reductase [EC:1.6.5.5] (A)"	--	[CR]	Energy production and conversion;; General function prediction only	Zinc-binding dehydrogenase;; Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	Quinone oxidoreductase GN=CRYZ OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: quinone oxidoreductase [Galeopterus variegatus]
ENSG00000116793(PHTF1)	--	10.61955528	462	11.04621933	547	10.45029279	488	10.27441561	485	12.07963352	517	10.59453633	496	0.970513348	0.039132615	normal	0.966767372	-0.102511537	normal	0.971580762	0.015121051	normal	0.961493642	-0.020222369	normal	--	--	--	--	--	--	--	Male germ-cell putative homeodomain transcription factor	Putative homeodomain transcription factor 1 GN=PHTF1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: putative homeodomain transcription factor 1 isoform X2 [Felis catus]
ENSG00000116809(ZBTB17)	--	5.078573935	305	5.659367346	317	5.576943734	360	4.915154659	308	5.565470252	349	6.94761173	406	0.967792216	-0.016627804	normal	0.961015228	0.116786519	normal	0.955111986	0.164540162	normal	0.789634621	0.094255929	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10500|0|ggo:101133569|ZBTB17; zinc finger and BTB domain-containing protein 17 isoform 1; K10500 zinc finger and BTB domain-containing protein 17 (A)	Cell cycle (ko04110);; Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; BTB/POZ domain;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger and BTB domain-containing protein 17 GN=ZBTB17 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 17 isoform X1 [Orycteropus afer afer]
ENSG00000116815(CD58)	--	13.34792114	226	11.15048565	189	12.4215633	197	11.028555	192	13.191276	218	11.742131	201	0.928339328	-0.264098123	normal	0.950767461	0.183149935	normal	0.966859764	0.020552236	normal	0.970629192	-0.023410335	normal	--	--	--	"K06492|0|hsa:965|CD58, LFA-3, LFA3, ag3; CD58 molecule; K06492 CD58 antigen (A)"	Cell adhesion molecules (CAMs) (ko04514);; Epstein-Barr virus infection (ko05169)	--	--	--	Lymphocyte function-associated antigen 3 (Precursor) GN=CD58 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lymphocyte function-associated antigen 3 [Balaenoptera acutorostrata scammoni]
ENSG00000116819(TFAP2E)	--	0.292001	10	0.169995	6	0.083025	2	0.0289778	1	0.281262	9	0.402096	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K09179|0|hsa:339488|TFAP2E, AP2E; transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon); K09179 transcription factor AP-2 epsilon (A)"	--	[K]	Transcription	Transcription factor AP-2	Transcription factor AP-2-epsilon OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor AP-2-epsilon [Dasypus novemcinctus]
ENSG00000116830(TTF2)	--	5.2358018	854	4.453262811	831	6.64241074	948	4.608083595	862	4.416529332	748	3.919789177	730	0.977646143	-0.017349397	normal	0.960961518	-0.172904917	normal	0.758763021	-0.38458084	normal	0.356402082	-0.191710744	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity (GO:0016787);; 	"K15173|0|hsa:8458|TTF2, HuF2, ZGRF6; transcription termination factor, RNA polymerase II; K15173 transcription termination factor 2 [EC:3.6.4.-] (A)"	Thyroid hormone synthesis (ko04918)	[KL]	"Transcription;; Replication, recombination and repair"	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; GRF zinc finger"	Transcription termination factor 2 GN=TTF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription termination factor 2 [Galeopterus variegatus]
ENSG00000116833(NR5A2)	--	18.58479564	1323	16.99828486	1230	16.06309135	1116	23.35772547	1675	27.0760619	1910	23.58036002	1676	0.90673504	0.309196043	normal	0.052506945	0.612878524	normal	0.093378896	0.577750545	normal	0.000694339	0.498614987	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08027|0|ptr:469631|NR5A2; nuclear receptor subfamily 5, group A, member 2; K08027 nuclear receptor subfamily 5 group A member 2 (A)"	Maturity onset diabetes of the young (ko04950)	[K]	Transcription	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Nuclear receptor subfamily 5 group A member 2 GN=NR5A2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor subfamily 5 group A member 2 isoform X3 [Ailuropoda melanoleuca]
ENSG00000116852(KIF21B)	--	0.957193897	198	0.74917635	155	0.86612567	184	0.622412113	128	0.7790747	161	0.926338895	193	0.274649509	-0.653824801	normal	0.965993303	0.033049528	normal	0.9657748	0.060121132	normal	0.671377813	-0.175710927	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10395|0|hsa:23046|KIF21B; kinesin family member 21B; K10395 kinesin family member 4/21/27 (A)	--	[Z]	Cytoskeleton	"Kinesin motor domain;; WD domain, G-beta repeat"	Kinesin-like protein KIF21B GN=KIF21B OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF21B isoform 1 [Odobenus rosmarus divergens]
ENSG00000116857(TMEM9)	--	71.6712087	1682	71.4659003	1509	63.9308731	1518	80.94183853	1894	83.22582399	1960	77.02530459	1819	0.979224187	0.14030554	normal	0.857305407	0.35552088	normal	0.950293573	0.252452265	normal	0.151114211	0.247347398	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	TMEM9	Transmembrane protein 9 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 9 isoform X1 [Tupaia chinensis] 
ENSG00000116863(ADPRHL2)	--	11.3081	332	11.5571	350	10.3307	312	14.8163	439	13.8264	401	13.5188	396	0.807074956	0.370709445	normal	0.951967443	0.174117486	normal	0.862472404	0.334221795	normal	0.230154175	0.292669515	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K11687|0|hsa:54936|ADPRHL2, ARH3; ADP-ribosylhydrolase like 2 (EC:3.2.1.143); K11687 poly(ADP-ribose) glycohydrolase ARH3 [EC:3.2.1.143] (A)"	--	--	--	ADP-ribosylglycohydrolase	Poly(ADP-ribose) glycohydrolase ARH3 (Precursor) GN=ADPRHL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: poly(ADP-ribose) glycohydrolase ARH3 [Oryctolagus cuniculus]
ENSG00000116871(MAP7D1)	--	39.29968349	2982	47.15992278	3045	41.57786606	3335	49.23160205	3513	48.8159445	3521	33.68705003	2560	0.978382186	0.205493427	normal	0.981171486	0.188029539	normal	0.819888367	-0.38963212	normal	0.972572149	0.013475867	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: microtubule cytoskeleton (GO:0015630);; 	K16806|0|ptr:456751|MAP7D1; MAP7 domain containing 1; K16806 MAP7 domain-containing protein 1 (A)	--	--	--	MAP7 (E-MAP-115) family	MAP7 domain-containing protein 1 GN=MAP7D1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MAP7 domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000116874(WARS2)	--	3.674335567	167	4.114233311	186	3.662984	168	3.728647	171	4.413932	201	3.474322	159	0.967389858	0.003286083	normal	0.962772453	0.089764153	normal	0.96490122	-0.086921509	normal	0.998023824	0.006027439	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01867|0|hsa:10352|WARS2, TrpRS; tryptophanyl tRNA synthetase 2, mitochondrial (EC:6.1.1.2); K01867 tryptophanyl-tRNA synthetase [EC:6.1.1.2] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class I (W and Y)	"Tryptophan--tRNA ligase, mitochondrial (Precursor) GN=WARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tryptophan--tRNA ligase, mitochondrial-like [Tursiops truncatus]"
ENSG00000116885(OSCP1)	--	3.50672801	72	3.7281884	80	1.972788892	52	2.255024173	59	2.952110019	58	2.81515076	63	0.957945882	-0.310774255	normal	0.90471601	-0.47478554	normal	0.967244078	0.26162667	normal	0.760492236	-0.202234179	normal	--	--	--	--	--	[S]	Function unknown	Organic solute transport protein 1	Protein OSCP1 GN=OSCP1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: protein OSCP1 isoform X1 [Camelus ferus] 
ENSG00000116898(MRPS15)	--	37.3378	629	40.6234	685	37.9725	643	38.596	660	38.8529	652	42.6802	722	0.973816217	0.038481979	normal	0.970483237	-0.092449347	normal	0.962337444	0.158536605	normal	0.914275011	0.034685693	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02956|4.34992e-168|hsa:64960|MRPS15, MPR-S15, RPMS15, S15mt; mitochondrial ribosomal protein S15; K02956 small subunit ribosomal protein S15 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S15	"28S ribosomal protein S15, mitochondrial (Precursor) GN=MRPS15 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S15, mitochondrial-like [Galeopterus variegatus]"
ENSG00000116903(EXOC8)	--	6.23522	534	6.69753	578	6.73026	574	5.69644	491	5.40952	462	6.2012	532	0.960000955	-0.151494217	normal	0.842403187	-0.343595313	normal	0.966228668	-0.117594029	normal	0.385602406	-0.204081988	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vps51/Vps67	Exocyst complex component 8 GN=EXOC8 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 8 [Ailuropoda melanoleuca]
ENSG00000116906(GNPAT)	--	28.52316032	1168	28.44581487	1236	28.11039236	1200	26.83845728	1106	32.84414994	1339	30.6258307	1229	0.976377198	-0.109373269	normal	0.978868118	0.093940213	normal	0.98158184	0.026126533	normal	0.98598528	0.006929718	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K00649|0|hsa:8443|GNPAT, DAP-AT, DAPAT, DHAPAT; glyceronephosphate O-acyltransferase (EC:2.3.1.42); K00649 glyceronephosphate O-acyltransferase [EC:2.3.1.42] (A)"	Glycerophospholipid metabolism (ko00564);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Acyltransferase	Dihydroxyacetone phosphate acyltransferase GN=GNPAT OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: dihydroxyacetone phosphate acyltransferase isoform X1 [Oryctolagus cuniculus]
ENSG00000116918(TSNAX)	--	25.57041021	995	26.80081114	1044	25.75640702	984	27.76526497	1083	26.70630755	1039	23.83561453	931	0.976725281	0.091297401	normal	0.97927551	-0.028311507	normal	0.976023491	-0.088029481	normal	0.985893701	-0.007452005	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: sequence-specific DNA binding (GO:0043565);; 	--	--	[R]	General function prediction only	Translin family	Translin-associated protein X GN=TSNAX OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: translin-associated protein X [Condylura cristata]
ENSG00000116922(C1orf109)	--	12.4523858	326	12.59437416	302	13.067061	374	13.3995297	355	13.5924496	325	12.5375647	336	0.964653722	0.091700583	normal	0.963928132	0.084058801	normal	0.95520335	-0.16217626	normal	1	-0.00103163	normal	--	--	--	--	--	--	--	Casein Kinase 2 substrate	Uncharacterized protein C1orf109 GN=C1orf109 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf109 homolog [Pteropus alecto]
ENSG00000116954(RRAGC)	--	14.6764	573	18.25456	705	13.37878	505	18.46777	704	16.65448	629	23.91984	923	0.920222732	0.265564714	normal	0.955270413	-0.185568096	normal	0.00014837	0.859822942	normal	0.378310302	0.318593289	normal	--	--	Molecular Function: GTP binding (GO:0005525);; 	K16186|0|pps:100992406|RRAGC; Ras-related GTP binding C; K16186 Ras-related GTP-binding protein C/D (A)	mTOR signaling pathway (ko04150)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Gtr1/RagA G protein conserved region;; ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit	Ras-related GTP-binding protein C OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related GTP-binding protein C isoform 1 [Ceratotherium simum simum] 
ENSG00000116957(TBCE)	--	21.927548	817	21.572648	808	20.4180942	761	22.19218346	842	23.1667811	860	21.9293583	824	0.97730287	0.012628498	normal	0.975013102	0.068430655	normal	0.971967844	0.106253478	normal	0.827714025	0.060913163	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	CAP-Gly domain;; Leucine Rich repeats (2 copies);; Ribosomal protein S21e;; Leucine rich repeat;; Leucine Rich repeat;; Ubiquitin-like domain;; Leucine rich repeat;; Leucine Rich Repeat	Tubulin-specific chaperone E GN=TBCE OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin-specific chaperone E isoform X1 [Ursus maritimus]
ENSG00000116962(NID1)	--	2.011384836	237	1.422779806	166	1.654124227	193	5.11832195	597	5.85927239	681	3.567228588	421	1.29E-09	1.29653587	up	0	2.005281977	up	3.05E-06	1.110887629	up	1.67E-05	1.489316854	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: cell-matrix adhesion (GO:0007160);; 	"K06826|0|hsa:4811|NID1, NID; nidogen 1; K06826 nidogen (entactin) (A)"	--	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	G2F domain;; Low-density lipoprotein receptor repeat class B;; EGF domain;; Nidogen-like;; Thyroglobulin type-1 repeat;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; Coagulation Factor Xa inhibitory site;; EGF-like domain	Nidogen-1 (Precursor) GN=NID1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: nidogen-1 [Equus przewalskii]
ENSG00000116977(LGALS8)	--	14.63841176	718	16.31596988	901	13.11552127	659	17.81418685	950	15.53174664	787	22.93270487	1069	0.786484978	0.372416682	normal	0.94978186	-0.216201396	normal	0.010047243	0.688367955	normal	0.335691709	0.279427793	normal	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	"K06832|0|hsa:3964|LGALS8, Gal-8, PCTA-1, PCTA1, Po66-CBP; lectin, galactoside-binding, soluble, 8; K06832 galectin-8 (A)"	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-8 GN=LGALS8 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: galectin-8 isoform X3 [Oryctolagus cuniculus]
ENSG00000116981(NT5C1A)	--	0	0	0	0	0	0	0	0	0.111868	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: magnesium ion binding (GO:0000287);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: 5'-nucleotidase activity (GO:0008253);; Biological Process: nucleotide metabolic process (GO:0009117);; 	"K01081|0|hsa:84618|NT5C1A, CN-I, CN-IA, CN1, CN1A, CNI; 5'-nucleotidase, cytosolic IA (EC:3.1.3.5); K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	--	--	5'-nucleotidase	Cytosolic 5'-nucleotidase 1A GN=NT5C1A OS=Homo sapiens (Human) PE=2 SV=1	F	Nucleotide transport and metabolism	PREDICTED: cytosolic 5'-nucleotidase 1A [Orycteropus afer afer]
ENSG00000116983(HPCAL4)	--	0.150793688	13	0.068102187	6	0.061874751	4	0.088161864	7	0.090280379	7	0.062433488	5	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain;; EF-hand domain pair;; EF-hand domain pair;; EF hand;; Secreted protein acidic and rich in cysteine Ca binding region	Hippocalcin-like protein 4 GN=HPCAL4 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: hippocalcin-like protein 4 [Odobenus rosmarus divergens]
ENSG00000116984(MTR)	--	8.413830266	1244	8.893543131	1387	9.361913735	1279	10.99532574	1479	8.618344832	1328	8.103976233	1222	0.958660311	0.218555513	normal	0.980190078	-0.084045537	normal	0.980224792	-0.073973928	normal	0.945323837	0.02140231	normal	[E]	Amino acid transport and metabolism	Molecular Function: methionine synthase activity (GO:0008705);; Biological Process: methionine biosynthetic process (GO:0009086);; Molecular Function: cobalamin binding (GO:0031419);; Biological Process: pteridine-containing compound metabolic process (GO:0042558);; Molecular Function: metal ion binding (GO:0046872);; 	"K00548|0|hsa:4548|MTR, HMAG, MS, cblG; 5-methyltetrahydrofolate-homocysteine methyltransferase (EC:2.1.1.13); K00548 5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13] (A)"	Cysteine and methionine metabolism (ko00270);; Selenocompound metabolism (ko00450);; One carbon pool by folate (ko00670);; Biosynthesis of amino acids (ko01230)	--	--	"Homocysteine S-methyltransferase;; Vitamin B12 dependent methionine synthase, activation domain;; Pterin binding enzyme;; B12 binding domain;; B12 binding domain"	Methionine synthase GN=MTR OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: methionine synthase isoform 1 [Ceratotherium simum simum]
ENSG00000116985(BMP8B)	--	5.07105	468	3.75676	350	4.27146	398	3.90564	359	4.22742	388	3.63079	335	0.715110765	-0.411808132	normal	0.960370204	0.126754844	normal	0.923774181	-0.255837809	normal	0.492784192	-0.189761519	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K16622|0|hsa:656|BMP8B, BMP8, OP2; bone morphogenetic protein 8b; K16622 bone morphogenetic protein 8 (A)"	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Bone morphogenetic protein 8B (Precursor) GN=BMP8B OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein 8B [Sus scrofa]
ENSG00000116990(MYCL)	--	0.68731129	39	0.374767163	22	0.692296579	40	0.409499386	27	0.589290288	33	1.449274352	33	0.957761468	-0.535831496	normal	0.965386526	0.533427165	normal	0.976928556	-0.274387083	normal	0.890794781	-0.138986725	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09110|0|ptr:469291|MYCL, MYCL1; v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog; K09110 L-myc proto-oncogene protein (A)"	--	--	--	Myc amino-terminal region;; Helix-loop-helix DNA-binding domain	Protein L-Myc GN=MYCL OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: protein L-Myc-1 isoform X6 [Canis lupus familiaris]
ENSG00000116991(SIPA1L2)	--	4.784318527	713	5.613635979	820	4.33672002	661	2.483096412	358	3.444914582	526	3.093736343	474	2.58E-06	-1.021602747	down	0.027965591	-0.660453576	normal	0.429740757	-0.486733384	normal	0.000365649	-0.712649791	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	"K17702|0|hsa:57568|SIPA1L2, SPAL2; signal-induced proliferation-associated 1 like 2; K17702 signal-induced proliferation-associated 1 like protein 2 (A)"	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3401);; Rap/ran-GAP;; PDZ domain (Also known as DHR or GLGF)	Signal-induced proliferation-associated 1-like protein 2 GN=SIPA1L2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: signal-induced proliferation-associated 1-like protein 2 [Oryctolagus cuniculus]
ENSG00000117000(RLF)	--	3.94241306	482	4.80095908	579	4.244183527	504	4.544321428	557	5.062247837	617	4.583548	560	0.954561353	0.177285902	normal	0.970822496	0.070103196	normal	0.962016522	0.143303558	normal	0.63377973	0.126692972	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc finger, C2H2 type"	Zinc finger protein Rlf GN=RLF OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein Rlf [Leptonychotes weddellii]
ENSG00000117009(KMO)	--	0.103328	8	0.1490483	4	0.103894	7	0.4668748	21	0.745758646	21	1.167609021	30	0.910248624	1.213437628	normal	0.385962273	2.012224139	normal	0.122100887	1.880939776	normal	0.004370924	1.902280229	up	--	--	Molecular Function: FAD binding (GO:0071949);; 	"K00486|0|hsa:8564|KMO, dJ317G22.1; kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) (EC:1.14.13.9); K00486 kynurenine 3-monooxygenase [EC:1.14.13.9] (A)"	Tryptophan metabolism (ko00380)	[CR]	Energy production and conversion;; General function prediction only	FAD binding domain;; NAD(P)-binding Rossmann-like domain	Kynurenine 3-monooxygenase {ECO:0000255|HAMAP-Rule:MF_03018} OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: LOW QUALITY PROTEIN: kynurenine 3-monooxygenase [Physeter catodon]
ENSG00000117010(ZNF684)	--	1.732324	52	1.421213526	39	2.396410467	65	1.445818671	40	0.597252536	19	1.3252039	36	0.960344372	-0.395962975	normal	0.751132929	-1.002108043	normal	0.630036073	-0.834287685	normal	0.179626905	-0.736692166	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:127396|ZNF684; zinc finger protein 684; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 684 GN=ZNF684 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 684 isoform X1 [Equus przewalskii] 
ENSG00000117013(KCNQ4)	--	0.210510191	15	0.165116246	12	0.107170396	7	0.139502443	10	0.107503251	7	0.2412311	11	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04929|0|hsa:9132|KCNQ4, DFNA2, DFNA2A, KV7.4; potassium voltage-gated channel, KQT-like subfamily, member 4; K04929 potassium voltage-gated channel KQT-like subfamily member 4 (A)"	Cholinergic synapse (ko04725)	[P]	Inorganic ion transport and metabolism	KCNQ voltage-gated potassium channel;; Ion transport protein;; Ion channel	Potassium voltage-gated channel subfamily KQT member 4 GN=KCNQ4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	"Potassium voltage-gated channel subfamily KQT member 4, partial [Pteropus alecto]"
ENSG00000117016(RIMS3)	--	3.683875658	515	2.728139081	377	3.581103033	392	1.756249417	243	2.032063665	239	1.7018661	185	8.71E-07	-1.109510091	down	0.065440069	-0.675545922	normal	8.48E-06	-1.085379897	down	9.84E-05	-0.966970536	normal	--	--	--	K15298|0|cjc:100407449|RIMS3; regulating synaptic membrane exocytosis 3; K15298 regulating synaptic membrane exocytosis protein 3 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Regulating synaptic membrane exocytosis protein 3 GN=RIMS3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: regulating synaptic membrane exocytosis protein 3 isoform X1 [Tupaia chinensis] 
ENSG00000117020(AKT3)	--	15.35443758	1422	16.37979255	1560	15.38948259	1387	17.0463475	1630	15.85495803	1504	14.72331474	1534	0.973369885	0.165950673	normal	0.982160614	-0.07409486	normal	0.976908032	0.136897269	normal	0.758315786	0.073955725	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04456|0|tup:102474297|AKT3; v-akt murine thymoma viral oncogene homolog 3; K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Tight junction (ko04530);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Carbohydrate digestion and absorption (ko04973);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PH domain;; Kinase-like;; Protein kinase C terminal domain	RAC-gamma serine/threonine-protein kinase GN=AKT3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: RAC-gamma serine/threonine-protein kinase [Oryctolagus cuniculus]
ENSG00000117036(ETV3)	--	7.09112	599	8.46897	746	6.62109	564	8.49626	738	8.97607	743	8.75879	722	0.918166731	0.269608634	normal	0.975267044	-0.027184758	normal	0.83334257	0.347187456	normal	0.402102147	0.185056472	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09433|0|hsa:2117|ETV3, METS, PE-1, PE1, bA110J1.4; ets variant 3; K09433 ETS translocation variant 3 (A)"	--	[K]	Transcription	Ets-domain	ETS translocation variant 3 GN=ETV3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS translocation variant 3 [Lipotes vexillifer]
ENSG00000117054(ACADM)	--	17.82997582	693	17.96347658	640	19.95571045	693	17.46938575	638	17.33185317	593	16.25821751	573	0.963499271	-0.149784943	normal	0.965002715	-0.131144322	normal	0.908718978	-0.281933972	normal	0.402102147	-0.188873373	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00249|0|mcc:705168|ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; K00249 acyl-CoA dehydrogenase [EC:1.3.8.7] (A)"	"Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320)"	[I]	Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (Precursor) GN=ACADM OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: medium-chain specific acyl-CoA dehydrogenase, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000117069(ST6GALNAC5)	--	0.016633	1	0.0501118	3	0.0330147	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03375|0|hsa:81849|ST6GALNAC5, SIAT7E, ST6GalNAcV; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; K03375 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7E) [EC:2.4.99.-] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 GN=ST6GALNAC5 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 [Loxodonta africana]"
ENSG00000117114(ADGRL2)	--	2.04028425	230	1.811386363	189	2.12290679	234	5.609138981	631	6.544072103	724	3.860627422	436	1.19E-11	1.419216653	up	0	1.907796799	up	0.000661431	0.885270709	normal	5.21E-05	1.433827393	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: carbohydrate binding (GO:0030246);; 	K04593|0|mcf:102130272|LPHN2; latrophilin 2; K04593 latrophilin 2 (A)	--	[T]	Signal transduction mechanisms	Latrophilin Cytoplasmic C-terminal region;; Olfactomedin-like domain;; Domain of unknown function (DUF3497);; 7 transmembrane receptor (Secretin family);; Galactose binding lectin domain;; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain	Latrophilin-2 (Precursor) GN=LPHN2 OS=Homo sapiens (Human) PE=1 SV=2	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: latrophilin-2 isoform X2 [Mustela putorius furo]
ENSG00000117115(PADI2)	--	11.683118	976	8.666057	734	10.16058525	868	3.523236369	300	3.989113	330	2.75889625	235	0	-1.727547478	down	3.20E-08	-1.171042753	down	0	-1.886548996	down	2.12E-14	-1.597159664	down	--	--	Molecular Function: protein-arginine deiminase activity (GO:0004668);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein citrullination (GO:0018101);; 	"K01481|0|pps:100989222|PADI2; peptidyl arginine deiminase, type II; K01481 protein-arginine deiminase [EC:3.5.3.15] (A)"	--	--	--	Protein-arginine deiminase (PAD);; Protein-arginine deiminase (PAD) middle domain;; Protein-arginine deiminase (PAD) N-terminal domain	Protein-arginine deiminase type-2 GN=PADI2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein-arginine deiminase type-2 isoform X1 [Vicugna pacos]
ENSG00000117118(SDHB)	--	51.7393518	1016	44.77397043	887	50.99350898	1020	44.88182248	905	44.57043422	869	45.50178394	907	0.9583057	-0.197426395	normal	0.976522656	-0.050916778	normal	0.963629057	-0.17740703	normal	0.50586514	-0.145723332	normal	[C]	Energy production and conversion	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	"K00235|0|ptr:456526|SDHB; succinate dehydrogenase complex, subunit B, iron sulfur (Ip); K00235 succinate dehydrogenase (ubiquinone) iron-sulfur subunit [EC:1.3.5.1] (A)"	Citrate cycle (TCA cycle) (ko00020);; Oxidative phosphorylation (ko00190);; Carbon metabolism (ko01200);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	2Fe-2S iron-sulfur cluster binding domain;; 4Fe-4S dicluster domain;; 4Fe-4S dicluster domain;; 4Fe-4S dicluster domain	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (Precursor) GN=SDHB OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial [Loxodonta africana]"
ENSG00000117122(MFAP2)	--	0	0	0	0	0	0	0.101363426	2	0.248885407	4	0.177208547	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: microfibril (GO:0001527);; 	--	--	--	--	Microfibril-associated glycoprotein (MAGP);; ShK domain-like	Microfibrillar-associated protein 2 (Precursor) GN=MFAP2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: microfibrillar-associated protein 2 isoform X1 [Galeopterus variegatus] 
ENSG00000117133(RPF1)	--	16.38298	398	14.533451	348	16.57186	391	17.576023	434	19.472241	470	14.412005	352	0.965886685	0.093747729	normal	0.726377343	0.410606346	normal	0.956012276	-0.15923519	normal	0.688756215	0.122025321	normal	[JA]	"Translation, ribosomal structure and biogenesis;; RNA processing and modification"	--	K14846|0|ggo:101138386|RPF1; ribosome production factor 1; K14846 ribosome production factor 1 (A)	--	[A]	RNA processing and modification	Brix domain	Ribosome production factor 1 GN=RPF1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosome production factor 1 [Equus przewalskii]
ENSG00000117139(KDM5B)	--	13.32862178	1714	13.46462153	1760	13.30792185	1704	11.95295509	1544	14.15179281	1827	14.14189681	1830	0.971694171	-0.181355229	normal	0.985193954	0.032447283	normal	0.98302259	0.094545888	normal	0.964739885	-0.014286152	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K11446|0|hsa:10765|KDM5B, CT31, JARID1B, PLU-1, PLU1, PPP1R98, PUT1, RBBP2H1A; lysine (K)-specific demethylase 5B; K11446 histone demethylase JARID1 [EC:1.14.11.-] (A)"	--	[R]	General function prediction only	"PLU-1-like protein;; JmjC domain, hydroxylase;; PHD-finger;; ARID/BRIGHT DNA binding domain;; C5HC2 zinc finger;; jmjN domain"	Lysine-specific demethylase 5B GN=KDM5B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: lysine-specific demethylase 5B [Galeopterus variegatus]
ENSG00000117143(UAP1)	--	12.164996	489	10.026767	401	11.0815839	456	17.1021771	694	14.08652427	576	11.23898572	441	0.477428276	0.47301583	normal	0.419695176	0.499460561	normal	0.96936908	-0.056356545	normal	0.314080842	0.323713181	normal	--	--	Biological Process: metabolic process (GO:0008152);; Molecular Function: uridylyltransferase activity (GO:0070569);; 	K00972|0|pps:100986482|UAP1; UDP-N-acetylglucosamine pyrophosphorylase 1; K00972 UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	[M]	Cell wall/membrane/envelope biogenesis	UTP--glucose-1-phosphate uridylyltransferase	UDP-N-acetylglucosamine pyrophosphorylase GN=UAP1 OS=Homo sapiens (Human) PE=1 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: UDP-N-acetylhexosamine pyrophosphorylase isoform X2 [Equus caballus]
ENSG00000117148(ACTL8)	--	0.418787947	11	0.774091458	21	1.038670969	31	0.535556358	16	0.197028279	5	0.413901268	11	--	--	--	0.53672995	-1.807696997	normal	0.542690473	-1.385237032	normal	--	--	--	[Z]	Cytoskeleton	--	--	--	[Z]	Cytoskeleton	Actin	Actin-like protein 8 GN=ACTL8 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: actin-like protein 8 [Felis catus]
ENSG00000117151(CTBS)	--	5.50234	451	4.34323	350	4.81241	380	3.3513	279	3.65227	301	3.42081	282	0.018175172	-0.720541205	normal	0.931766128	-0.237908288	normal	0.681087653	-0.436571154	normal	0.032771801	-0.475405694	normal	[R]	General function prediction only	Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K12310|0|hsa:1486|CTBS, CTB; chitobiase, di-N-acetyl- (EC:3.2.1.-); K12310 Di-N-acetylchitobiase [EC:3.2.1.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 18	Di-N-acetylchitobiase (Precursor) GN=CTBS OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: di-N-acetylchitobiase [Tupaia chinensis]
ENSG00000117152(RGS4)	--	0.193389522	4	0.079925555	4	0.101730074	3	0.0619667	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16449|0|ptr:457470|RGS4; regulator of G-protein signaling 4; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 4 GN=RGS4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: regulator of G-protein signaling 4 [Lipotes vexillifer]
ENSG00000117153(KLHL12)	--	13.55811124	835	12.715385	796	14.164973	848	12.18605796	740	13.44929811	805	13.96479209	848	0.952548816	-0.204682795	normal	0.976422403	-0.005196389	normal	0.977681591	-0.008276682	normal	0.789634621	-0.071621644	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10450|0|ptr:457634|KLHL12; kelch-like family member 12; K10450 kelch-like protein 12 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 12 GN=KLHL12 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 12 isoformX1 [Canis lupus familiaris] 
ENSG00000117155(SSX2IP)	--	7.384199876	608	8.970481684	666	8.082404157	693	7.251699732	539	7.241521964	558	5.694586137	457	0.948022569	-0.204070167	normal	0.913122702	-0.275997909	normal	0.081078899	-0.607308563	normal	0.060691302	-0.361486841	normal	--	--	--	"K06085|0|hsa:117178|SSX2IP, ADIP; synovial sarcoma, X breakpoint 2 interacting protein; K06085 synovial sarcoma, X breakpoint 2 interacting protein (A)"	Adherens junction (ko04520)	--	--	Afadin- and alpha -actinin-Binding	Afadin- and alpha-actinin-binding protein GN=SSX2IP OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: afadin- and alpha-actinin-binding protein isoform X1 [Pteropus alecto] 
ENSG00000117174(ZNHIT6)	--	8.304981	468	7.935862	448	8.702165953	512	8.349885938	498	9.177296	505	8.430924646	493	0.969836006	0.058618385	normal	0.958716388	0.150878184	normal	0.970127449	-0.062658984	normal	0.895889478	0.046120329	normal	--	--	--	--	--	[R]	General function prediction only	HIT zinc finger	Box C/D snoRNA protein 1 GN=ZNHIT6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: box C/D snoRNA protein 1 [Equus przewalskii]
ENSG00000117222(RBBP5)	--	8.86994	688	8.87645	694	9.27341	714	10.38379	810	10.66375	826	10.17466	793	0.951816732	0.204260341	normal	0.942696681	0.229321045	normal	0.966526524	0.1428182	normal	0.368489771	0.191547221	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14961|0|ssc:100513301|RBBP5; retinoblastoma binding protein 5; K14961 COMPASS component SWD1 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Retinoblastoma-binding protein 5 GN=RBBP5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: retinoblastoma-binding protein 5 isoform X1 [Tupaia chinensis] 
ENSG00000117226(GBP3)	--	2.149799	112	1.585303139	70	1.510017	98	5.1319087	336	4.892032544	324	4.541038007	301	1.66E-10	1.541334054	up	0	2.165298688	up	1.26E-10	1.595839437	up	5.21E-14	1.757828381	up	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	"Guanylate-binding protein, N-terminal domain;; Guanylate-binding protein, C-terminal domain"	Guanylate-binding protein 3 GN=GBP3 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: interferon-induced guanylate-binding protein 1-like [Equus caballus] 
ENSG00000117228(GBP1)	--	0.471267	32	0.678921	46	1.05306	71	3.15066	215	3.04839	207	2.01629	138	0	2.660790481	up	2.34E-13	2.11275194	up	0.036418589	0.93593475	normal	7.41E-07	1.888844652	up	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	"Guanylate-binding protein, C-terminal domain;; Guanylate-binding protein, N-terminal domain"	Interferon-induced guanylate-binding protein 1 (Precursor) GN=GBP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: interferon-induced guanylate-binding protein 1-like [Equus caballus] 
ENSG00000117245(KIF17)	--	1.012547372	87	0.667230308	57	0.705853589	61	0.319458641	27	0.322498745	27	0.364125236	31	9.91E-05	-1.663199572	down	0.354266577	-1.057737297	normal	0.483693661	-0.951153032	normal	0.004508526	-1.291073475	down	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10394|0|hsa:57576|KIF17, KIF17B, KIF3X, KLP-2, OSM-3; kinesin family member 17; K10394 kinesin family member 3/17 (A)"	--	--	--	Kinesin motor domain	Kinesin-like protein KIF17 GN=KIF17 OS=Homo sapiens (Human) PE=2 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF17 isoform X1 [Galeopterus variegatus]
ENSG00000117262(GPR89A)	--	2.3350425	73	2.77308	89	2.297930008	73	2.51104	81	2.26792	72	2.39469	77	0.971482634	0.116857711	normal	0.945165724	-0.321155413	normal	0.973148617	0.067312657	normal	0.954249112	-0.052641961	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[T]	Signal transduction mechanisms	Abscisic acid G-protein coupled receptor;; Protein of unknown function (DUF3735)	Golgi pH regulator B GN=GPR89B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: Golgi pH regulator-like isoform X1 [Bos mutus] 
ENSG00000117266(CDK18)	--	1.485880348	92	0.801498537	49	0.675978876	42	0.830387297	51	2.332417968	136	1.046659995	60	0.294167417	-0.862337843	normal	4.36E-05	1.423866237	up	0.933662373	0.491406324	normal	0.737561593	0.4116152	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K15596|0|mcf:101865553|uncharacterized LOC101865553; K15596 cyclin-dependent kinase 18 [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Cyclin-dependent kinase 18 GN=CDK18 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: cyclin-dependent kinase 18 isoform 1 [Ceratotherium simum simum]
ENSG00000117280(RAB29)	--	19.13930536	851	18.96797823	867	20.91052862	917	20.26904464	959	23.02322349	981	25.19645645	1108	0.96925907	0.141299016	normal	0.966707398	0.156537776	normal	0.930640328	0.264275753	normal	0.349275176	0.189412053	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07916|3.90016e-150|ptr:469654|RAB29, RAB7L1; RAB29, member RAS oncogene family; K07916 Ras-related protein Rab-7L1 (A)"	--	[T]	Signal transduction mechanisms	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-7L1 GN=RAB29 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras-related protein Rab-7L1 isoform 1 [Dasypus novemcinctus] 
ENSG00000117281(CD160)	--	0.329999	10	0.1075563	5	0.262711	9	0.184766	11	0.180952	10	0.438207	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06542|9.42866e-161|pps:100971035|CD160; CD160 molecule; K06542 CD160 antigen (A)	--	--	--	--	CD160 antigen (Precursor) GN=CD160 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: CD160 antigen [Loxodonta africana]
ENSG00000117298(ECE1)	--	29.97108818	3313	27.37012016	3152	30.52303919	3228	38.76907178	4404	45.26346804	5038	37.1469363	4226	0.862593104	0.37969084	normal	0.02381556	0.654906359	normal	0.858975798	0.380204621	normal	0.001468267	0.474569996	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K01415|0|pps:100969625|ECE1; endothelin converting enzyme 1; K01415 endothelin-converting enzyme [EC:3.4.24.71] (A)	--	[E]	Amino acid transport and metabolism	Peptidase family M13;; Peptidase family M13	Endothelin-converting enzyme 1 GN=ECE1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: endothelin-converting enzyme 1 isoform 1 [Trichechus manatus latirostris]
ENSG00000117305(HMGCL)	--	14.01138314	359	11.05980685	253	15.59829558	392	14.77862461	370	13.86244325	355	18.33197707	456	0.96890839	0.012655812	normal	0.624890275	0.464899031	normal	0.943770153	0.209139999	normal	0.553066883	0.214185638	normal	[E]	Amino acid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; 	K01640|0|pps:100987057|HMGCL; 3-hydroxymethyl-3-methylglutaryl-CoA lyase; K01640 hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] (A)	"Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Butanoate metabolism (ko00650);; Peroxisome (ko04146)"	[CE]	Energy production and conversion;; Amino acid transport and metabolism	HMGL-like	"Hydroxymethylglutaryl-CoA lyase, mitochondrial (Precursor) GN=HMGCL OS=Homo sapiens (Human) PE=1 SV=2"	CE	Energy production and conversion;; Amino acid transport and metabolism	"PREDICTED: hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2 [Galeopterus variegatus]"
ENSG00000117308(GALE)	--	39.62083961	1067	36.76690279	959	37.86974264	1027	37.96135369	999	37.71990149	998	46.33354314	1220	0.973318622	-0.125648817	normal	0.978341983	0.036026752	normal	0.946245591	0.239829132	normal	0.841523796	0.054928528	normal	[M]	Cell wall/membrane/envelope biogenesis	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K01784|0|hsa:2582|GALE, SDR1E1; UDP-galactose-4-epimerase (EC:5.1.3.2); K01784 UDP-glucose 4-epimerase [EC:5.1.3.2] (A)"	Galactose metabolism (ko00052);; Amino sugar and nucleotide sugar metabolism (ko00520)	[M]	Cell wall/membrane/envelope biogenesis	NAD dependent epimerase/dehydratase family;; UDP-glucose 4-epimerase C-term subunit;; 3-beta hydroxysteroid dehydrogenase/isomerase family;; RmlD substrate binding domain;; short chain dehydrogenase;; Male sterility protein;; Polysaccharide biosynthesis protein;; NADH(P)-binding;; KR domain;; NmrA-like family	UDP-glucose 4-epimerase {ECO:0000303|PubMed:22654673} OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: UDP-glucose 4-epimerase isoform X1 [Pteropus alecto] 
ENSG00000117318(ID3)	--	147.32	2775	194.81	3725	159.855	3101	148.099	2816	199.27	3761	159.857	3048	0.989687394	-0.009667388	normal	0.991480598	-0.007547628	normal	0.990188637	-0.033145761	normal	0.971889593	-0.017378815	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K17694|1.62558e-66|hsa:3399|ID3, HEIR-1, bHLHb25; inhibitor of DNA binding 3, dominant negative helix-loop-helix protein; K17694 DNA-binding protein inhibitor ID3 (A)"	TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	--	--	Helix-loop-helix DNA-binding domain	DNA-binding protein inhibitor ID-3 GN=ID3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-binding protein inhibitor ID-3 [Trichechus manatus latirostris] 
ENSG00000117322(CR2)	--	0	0	0	0	0	0	0	0	0	0	0.013802644	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04012|0|hsa:1380|CR2, C3DR, CD21, CR, CVID7, SLEB9; complement component (3d/Epstein Barr virus) receptor 2; K04012 complement receptor type 2 (A)"	Complement and coagulation cascades (ko04610);; Hematopoietic cell lineage (ko04640);; B cell receptor signaling pathway (ko04662);; Epstein-Barr virus infection (ko05169)	--	--	Sushi domain (SCR repeat)	Complement receptor type 2 (Precursor) GN=CR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: complement receptor type 2 isoform X7 [Balaenoptera acutorostrata scammoni]
ENSG00000117335(CD46)	--	106.2618236	5289	111.8789141	5510	107.9800899	5239	102.8594697	5144	95.654488	4750	129.35367	6406	0.992958389	-0.070915706	normal	0.97979407	-0.235481678	normal	0.969880739	0.281767223	normal	0.998167054	0.002746433	normal	--	--	--	K04007|0|ptr:469663|CD46; membrane cofactor protein; K04007 membrane cofactor protein (A)	Complement and coagulation cascades (ko04610);; Measles (ko05162)	--	--	Sushi domain (SCR repeat)	Membrane cofactor protein (Precursor) GN=CD46 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: membrane cofactor protein isoform X2 [Galeopterus variegatus]
ENSG00000117360(PRPF3)	--	15.7573	952	19.5108	1177	18.389	1107	16.492	998	17.1827	1033	20.3409	1232	0.978730473	0.037187361	normal	0.957348306	-0.209413169	normal	0.972505676	0.145866621	normal	0.983454676	-0.008550748	normal	--	--	Biological Process: mRNA processing (GO:0006397);; 	K12843|0|umr:103667552|PRPF3; pre-mRNA processing factor 3; K12843 U4/U6 small nuclear ribonucleoprotein PRP3 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	pre-mRNA processing factor 3 (PRP3);; Protein of unknown function (DUF1115);; PWI domain	U4/U6 small nuclear ribonucleoprotein Prp3 GN=PRPF3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp3 isoform X1 [Orycteropus afer afer]
ENSG00000117362(APH1A)	--	72.380795	2103	76.433753	2212	75.200801	2220	97.703526	2877	92.526474	2626	91.944617	2699	0.713112387	0.421020198	normal	0.968685869	0.225947056	normal	0.950899238	0.273404693	normal	0.057823142	0.306416342	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein processing (GO:0016485);; Biological Process: positive regulation of catalytic activity (GO:0043085);; 	K06172|1.41403e-173|pps:100982207|APH1A; APH1A gamma secretase subunit; K06172 anterior pharynx defective 1 (A)	Notch signaling pathway (ko04330);; Alzheimer's disease (ko05010)	[S]	Function unknown	Aph-1 protein	Gamma-secretase subunit APH-1A GN=APH1A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: gamma-secretase subunit APH-1A [Oryctolagus cuniculus] 
ENSG00000117385(P3H1)	--	17.29135484	773	14.47270312	654	14.66959755	667	18.23860152	746	26.053719	980	18.15302569	801	0.973463694	-0.081959203	normal	0.160264959	0.560998167	normal	0.929167269	0.255295152	normal	0.263909742	0.250217703	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K08134|0|hsa:64175|P3H1, GROS1, LEPRE1, OI8; prolyl 3-hydroxylase 1 (EC:1.14.11.7); K08134 leucine proline-enriched proteoglycan (leprecan) (A)"	--	[S]	Function unknown	2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily;; Tetratricopeptide repeat	Prolyl 3-hydroxylase 1 (Precursor) GN=LEPRE1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: prolyl 3-hydroxylase 1 [Pteropus alecto] 
ENSG00000117394(SLC2A1)	--	50.88400661	3217	51.99653517	3311	46.34405034	2971	118.0865026	7412	72.99359534	4583	91.13192678	5741	1.16E-10	1.172935385	up	0.689215199	0.447424325	normal	1.89E-06	0.941711024	normal	0.005233572	0.878444913	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K07299|0|pps:100991584|SLC2A1; solute carrier family 2 (facilitated glucose transporter), member 1; K07299 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 1 (A)"	HIF-1 signaling pathway (ko04066);; Insulin secretion (ko04911);; Thyroid hormone signaling pathway (ko04919);; Adipocytokine signaling pathway (ko04920);; Bile secretion (ko04976);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 1 GN=SLC2A1 OS=Homo sapiens (Human) PE=1 SV=2"	P	Inorganic ion transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 1 [Camelus bactrianus] "
ENSG00000117395(EBNA1BP2)	--	57.00215	1562	57.33806	1606	62.1154	1748	63.48624	1791	55.63863	1522	46.43886	1288	0.974775292	0.166385698	normal	0.980945138	-0.098834475	normal	0.563598895	-0.448410273	normal	0.626774061	-0.117556706	normal	--	--	--	"K14823|0|hsa:10969|EBNA1BP2, EBP2, NOBP, P40; EBNA1 binding protein 2; K14823 rRNA-processing protein EBP2 (A)"	--	[A]	RNA processing and modification	Eukaryotic rRNA processing protein EBP2	Probable rRNA-processing protein EBP2 GN=EBNA1BP2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable rRNA-processing protein EBP2 isoform 2 [Ceratotherium simum simum]
ENSG00000117399(CDC20)	--	56.61546	1775	49.62673	1594	55.86844	1793	63.73695	2014	67.43917	2112	41.9353	1334	0.97871046	0.151289402	normal	0.805407066	0.384214042	normal	0.62248117	-0.434481806	normal	0.894915588	0.058898961	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03363|0|pps:100985744|CDC20; cell division cycle 20; K03363 cell division cycle 20, cofactor of APC complex (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Cell division cycle protein 20 homolog GN=CDC20 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cell division cycle protein 20 homolog isoform X2 [Tupaia chinensis] 
ENSG00000117400(MPL)	--	0	0	0	0	0	0	0	0	0.0270627	0	0.05500677	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05082|0|hsa:4352|MPL, C-MPL, CD110, MPLV, THCYT2, TPOR; MPL proto-oncogene, thrombopoietin receptor; K05082 thrombopoietin receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	"Erythropoietin receptor, ligand binding;; Fibronectin type III domain;; Interleukin-6 receptor alpha chain, binding"	Thrombopoietin receptor (Precursor) GN=MPL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: thrombopoietin receptor isoform X1 [Galeopterus variegatus]
ENSG00000117407(ARTN)	--	0.86798388	7	0.659597194	7	0.233017507	4	0.571358219	10	1.105652386	11	0.471107962	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	--	--	--	--	Transforming growth factor beta like domain	Artemin (Precursor) GN=ARTN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: artemin-like [Sus scrofa]
ENSG00000117408(IPO13)	--	6.772578	483	9.012989	659	7.5079622	554	9.533919	676	8.563512	608	10.176165	721	0.555241645	0.452944917	normal	0.964433625	-0.137305543	normal	0.789760774	0.370931821	normal	0.314822377	0.220300679	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Exportin 1-like protein;; Importin-beta N-terminal domain	Importin-13 GN=IPO13 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin-13 isoform X1 [Oryctolagus cuniculus]
ENSG00000117410(ATP6V0B)	--	63.222036	1002	68.11179003	1115	60.37133402	953	73.28851404	1166	60.20104697	901	76.079307	1250	0.963094222	0.187586192	normal	0.872865632	-0.328374744	normal	0.770962458	0.382556916	normal	0.771780409	0.090342068	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting two-sector ATPase complex, proton-transporting domain (GO:0033177);; "	"K03661|1.46759e-164|mcf:102121430|ATP6V0B; ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b; K03661 V-type H+-transporting ATPase 21kDa proteolipid subunit (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Tuberculosis (ko05152);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase subunit C	V-type proton ATPase 21 kDa proteolipid subunit GN=ATP6V0B OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase 21 kDa proteolipid subunit isoform X9 [Mustela putorius furo] 
ENSG00000117411(B4GALT2)	--	27.37067122	1017	27.647679	1047	30.41130847	1169	30.254282	1128	32.50703039	1211	25.78031449	971	0.974644533	0.118445173	normal	0.963515247	0.188257854	normal	0.924506293	-0.275631335	normal	0.971889593	0.012632838	normal	--	--	--	"K07967|0|mcf:102115300|B4GALT2; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2; K07967 beta-1,4-galactosyltransferase 2 [EC:2.4.1.22 2.4.1.90 2.4.1.38 2.4.1.-] (A)"	Galactose metabolism (ko00052);; N-Glycan biosynthesis (ko00510);; Other types of O-glycan biosynthesis (ko00514);; Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	N-terminal region of glycosyl transferase group 7;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	"Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase GN=B4GALT2 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-galactosyltransferase 2 [Oryctolagus cuniculus] "
ENSG00000117419(ERI3)	--	35.1166223	837	36.74503019	838	34.61213346	858	32.80384512	814	38.05567141	885	31.6329139	788	0.975243488	-0.070899111	normal	0.976006142	0.057200202	normal	0.969552658	-0.130832752	normal	0.872762476	-0.047627337	normal	--	--	--	K18418|0|nle:100601018|ERI3; ERI1 exoribonuclease family member 3; K18418 ERI1 exoribonuclease 3 [EC:3.1.-.-] (A)	--	[L]	"Replication, recombination and repair"	Exonuclease	ERI1 exoribonuclease 3 GN=ERI3 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: ERI1 exoribonuclease 3 isoform X1 [Equus caballus] 
ENSG00000117425(PTCH2)	--	0.318345358	24	0.428104373	22	0.421192443	32	0.093420972	7	0.150151644	7	0.092017896	7	0.583873162	-1.607978949	normal	0.748807532	-1.484631144	normal	0.049201327	-1.984439256	normal	0.003008319	-1.913633599	down	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K11101|0|pps:100971308|PTCH2; patched 2; K11101 patched 2 (A)	Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Patched family;; Sterol-sensing domain of SREBP cleavage-activation	Protein patched homolog 2 GN=PTCH2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein patched homolog 2 [Orcinus orca]
ENSG00000117448(AKR1A1)	--	37.27600045	819	43.53334391	923	37.91239854	845	37.33115	842	36.63394685	816	51.54127003	1142	0.977347542	0.009107667	normal	0.955956289	-0.198841295	normal	0.636909477	0.4255904	normal	0.796816666	0.093770944	normal	[R]	General function prediction only	--	"K00002|0|pps:100990701|AKR1A1; aldo-keto reductase family 1, member A1 (aldehyde reductase); K00002 alcohol dehydrogenase (NADP+) [EC:1.1.1.2] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose and glucuronate interconversions (ko00040);; Glycerolipid metabolism (ko00561);; Degradation of aromatic compounds (ko01220)	[R]	General function prediction only	Aldo/keto reductase family	Alcohol dehydrogenase [NADP(+)] GN=AKR1A1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: alcohol dehydrogenase [NADP(+)] [Mustela putorius furo] 
ENSG00000117450(PRDX1)	--	853.082838	11616	901.1049002	12324	810.94237	10986	815.1510871	11410	824.96182	11156	747.63254	10311	0.996455812	-0.056639271	normal	0.994025637	-0.165056007	normal	0.995595051	-0.099759204	normal	0.659045708	-0.108864374	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: peroxiredoxin activity (GO:0051920);; Biological Process: oxidation-reduction process (GO:0055114);; 	K13279|1.60396e-145|ptr:456537|PRDX1; peroxiredoxin 1; K13279 peroxiredoxin 1 [EC:1.11.1.15] (A)	Peroxisome (ko04146)	[O]	"Posttranslational modification, protein turnover, chaperones"	AhpC/TSA family;; Redoxin;; C-terminal domain of 1-Cys peroxiredoxin	Peroxiredoxin-1 GN=PRDX1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	Peroxiredoxin-1 [Pteropus alecto]
ENSG00000117461(PIK3R3)	--	1.256079954	126	1.272108147	127	1.087788373	87	1.224054896	117	1.545159638	147	1.274300646	125	0.964037201	-0.136025578	normal	0.954902637	0.187484592	normal	0.805343228	0.507156803	normal	0.728258727	0.172713674	normal	--	--	--	"K02649|0|hsa:8503|PIK3R3, p55, p55-GAMMA, p55PIK; phosphoinositide-3-kinase, regulatory subunit 3 (gamma); K02649 phosphoinositide-3-kinase, regulatory subunit (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; Carbohydrate digestion and absorption (ko04973);; Bacterial invasion of epithelial cells (ko05100);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	SH2 domain	Phosphatidylinositol 3-kinase regulatory subunit gamma GN=PIK3R3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 3-kinase regulatory subunit gamma [Leptonychotes weddellii]
ENSG00000117472(TSPAN1)	--	0.724896	16	0.821854134	19	1.628946	35	2.763749	60	2.99682	65	1.710651	38	0.001446629	1.78198661	up	0.001710397	1.676739426	up	0.981847162	0.105958253	normal	0.017911522	1.198485333	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17348|7.2376e-138|hsa:10103|TSPAN1, NET1, TM4C, TM4SF; tetraspanin 1; K17348 tetraspanin-1 (A)"	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-1 GN=TSPAN1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: tetraspanin-1 isoform X1 [Mustela putorius furo] 
ENSG00000117475(BLZF1)	--	10.25959891	434	11.174909	510	11.89247865	496	11.01242492	466	11.01029714	483	12.81782691	560	0.968368605	0.071558155	normal	0.966304364	-0.099597089	normal	0.957485253	0.16631776	normal	0.894793169	0.046936903	normal	--	--	--	--	--	[S]	Function unknown	DASH complex subunit Hsk3 like	Golgin-45 GN=BLZF1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: golgin-45 [Ursus maritimus]
ENSG00000117477(CCDC181)	--	0.641243013	28	0.747735971	33	0.660465711	29	0.704907279	32	0.295853995	10	0.300351042	13	0.98401804	0.153909333	normal	0.21819035	-1.60348578	normal	0.850880666	-1.079769346	normal	0.2878226	-0.735312652	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 181 GN=CCDC181 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf114 homolog [Odobenus rosmarus divergens]
ENSG00000117479(SLC19A2)	--	5.013277	243	5.527829763	273	4.884355023	236	6.336537194	311	6.986112	337	7.669187	364	0.882881426	0.323315274	normal	0.910669362	0.281017794	normal	0.163209174	0.613669859	normal	0.097115559	0.40751723	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14610|0|ptr:469575|SLC19A2; solute carrier family 19 (thiamine transporter), member 2; K14610 solute carrier family 19 (thiamine transporter), member 2/3 (A)"	Vitamin digestion and absorption (ko04977)	[H]	Coenzyme transport and metabolism	Reduced folate carrier;; Major Facilitator Superfamily	Thiamine transporter 1 GN=SLC19A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: thiamine transporter 1 [Orycteropus afer afer]
ENSG00000117480(FAAH)	--	0.0532672	2	0.0512875	2	0.0253369	0	0.158015	6	0.155832	5	0.158485	6	--	--	--	--	--	--	--	--	--	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	--	"K15528|0|hsa:2166|FAAH, FAAH-1, PSAB; fatty acid amide hydrolase (EC:3.5.1.99); K15528 fatty acid amide hydrolase [EC:3.5.1.99] (A)"	Retrograde endocannabinoid signaling (ko04723)	[JIT]	"Translation, ribosomal structure and biogenesis;; Lipid transport and metabolism;; Signal transduction mechanisms"	Amidase	Fatty-acid amide hydrolase 1 GN=FAAH OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: fatty-acid amide hydrolase 1 [Equus caballus]
ENSG00000117481(NSUN4)	--	6.6092301	428	6.8916586	433	5.9430355	354	5.9449273	450	7.170411	441	7.659197	510	0.969726506	0.041337221	normal	0.96969692	0.004967881	normal	0.363887651	0.516607921	normal	0.485777474	0.184326451	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	hypothetical protein PANDA_008147 [Ailuropoda melanoleuca]
ENSG00000117500(TMED5)	--	21.41481217	1571	25.44159586	1671	25.50344069	1823	27.97608494	2016	23.60990448	1782	24.78696721	1871	0.892785234	0.328695813	normal	0.983614659	0.071296558	normal	0.985914437	0.029179661	normal	0.48846016	0.141272109	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	K14825|1.00667e-137|pps:100983472|TMED5; transmembrane emp24 protein transport domain containing 5; K14825 protein ERP2 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 5 (Precursor) GN=TMED5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 5 [Galeopterus variegatus]
ENSG00000117505(DR1)	--	13.72952891	780	14.11149808	831	14.265331	815	17.88805531	990	17.00085105	960	16.46067955	956	0.885300836	0.312574567	normal	0.959822705	0.186443481	normal	0.94887945	0.221539188	normal	0.2087405	0.239164438	normal	[K]	Transcription	--	--	--	[K]	Transcription	Histone-like transcription factor (CBF/NF-Y) and archaeal histone;; Core histone H2A/H2B/H3/H4	Protein Dr1 GN=DR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein Dr1 [Odobenus rosmarus divergens] 
ENSG00000117519(CNN3)	--	35.64821592	1319	32.52824243	1216	38.14340001	1409	48.572658	1813	52.63254101	1954	44.60545988	1665	0.648068303	0.427675631	normal	0.017024448	0.662205302	normal	0.956659654	0.232329486	normal	0.003328203	0.44065777	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Calponin family repeat;; Calponin homology (CH) domain	Calponin-3 GN=CNN3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	calponin-3 [Bos taurus] 
ENSG00000117523(PRRC2C)	--	28.93005219	7263	31.16700137	7700	30.34244956	7524	32.95582456	8090	33.51339709	8460	30.49511133	7612	0.993562207	0.124716854	normal	0.993946162	0.114351228	normal	0.995270218	0.008482576	normal	0.743840289	0.082318299	normal	--	--	--	--	--	[X]	--	BAT2 N-terminus	Protein PRRC2C GN=PRRC2C OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	hypothetical protein PANDA_018456 [Ailuropoda melanoleuca]
ENSG00000117525(F3)	--	1.49922	56	1.353742637	53	1.447954603	56	2.934388731	115	1.797532	69	1.626743827	64	0.047241542	0.988015466	normal	0.952204208	0.350393631	normal	0.972094027	0.17980857	normal	0.252103392	0.564739901	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03901|0|pps:100988955|F3; coagulation factor III (thromboplastin, tissue factor); K03901 coagulation factor III (tissue factor) (A)"	Complement and coagulation cascades (ko04610)	--	--	"Interferon-alpha/beta receptor, fibronectin type III;; Tissue factor"	Tissue factor (Precursor) GN=F3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tissue factor [Chrysochloris asiatica]
ENSG00000117528(ABCD3)	--	24.02281	1179	22.937332	1176	25.850613	1244	27.5792	1293	25.375715	1121	21.00728108	1086	0.97808915	0.102199094	normal	0.977676401	-0.090409243	normal	0.960184761	-0.203988196	normal	0.813353695	-0.061897492	normal	--	--	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05677|0|ptr:100615571|ABCD3; ATP-binding cassette, sub-family D (ALD), member 3; K05677 ATP-binding cassette, subfamily D (ALD), member 3 (A)"	ABC transporters (ko02010);; Peroxisome (ko04146)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC transporter transmembrane region 2;; ABC transporter	ATP-binding cassette sub-family D member 3 GN=ABCD3 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: ATP-binding cassette sub-family D member 3 isoform X1 [Orycteropus afer afer]
ENSG00000117533(VAMP4)	--	4.339463	206	3.182026974	178	4.680080179	216	3.000464596	148	2.773187072	170	3.232831237	167	0.660839803	-0.503427218	normal	0.963311844	-0.087012505	normal	0.857596635	-0.376468521	normal	0.331685186	-0.327520634	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K08513|1.40447e-70|tup:102475574|VAMP4; vesicle-associated membrane protein 4; K08513 vesicle-associated membrane protein 4 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Synaptobrevin	Vesicle-associated membrane protein 4 GN=VAMP4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein 4 [Tupaia chinensis]
ENSG00000117543(DPH5)	--	13.69500462	306	15.2591028	337	12.33896964	264	16.18259163	342	16.246781	336	14.71329511	327	0.960215055	0.129019454	normal	0.96727705	-0.025598872	normal	0.900272686	0.298919959	normal	0.704654063	0.126340047	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	K00586|0|ptr:457062|DPH5; diphthamide biosynthesis 5; K00586 diphthine synthase [EC:2.1.1.98] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Tetrapyrrole (Corrin/Porphyrin) Methylases	Diphthine synthase GN=DPH5 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: diphthine synthase isoform X1 [Lipotes vexillifer]
ENSG00000117569(PTBP2)	--	3.5033638	185	5.155643	268	4.3083757	208	4.8364559	240	6.637446	337	5.76328943	294	0.881146635	0.342176079	normal	0.892509525	0.307538567	normal	0.597988237	0.487942958	normal	0.228957328	0.377296709	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K14948|0|pon:100435447|PTBP2; polypyrimidine tract binding protein 2; K14948 polypyrimidine tract-binding protein 2 (A)	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Polypyrimidine tract-binding protein 2 GN=PTBP2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: polypyrimidine tract-binding protein 2 isoform X1 [Condylura cristata]
ENSG00000117586(TNFSF4)	--	0.09317864	5	0.01866992	1	0	0	0.037116671	2	0.0540073	2	0.03706678	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05469|3.78397e-132|pps:100971741|TNFSF4; tumor necrosis factor (ligand) superfamily, member 4; K05469 tumor necrosis factor ligand superfamily member 4 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNF(Tumour Necrosis Factor) family	Tumor necrosis factor ligand superfamily member 4 GN=TNFSF4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor ligand superfamily member 4 [Galeopterus variegatus]
ENSG00000117592(PRDX6)	--	113.002	2958	103.889	2703	111.629	2884	119.57	3136	109.978	2854	101.374	2655	0.98977281	0.053444282	normal	0.988658897	0.056966247	normal	0.985617561	-0.127580998	normal	0.990286694	-0.004863972	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: peroxiredoxin activity (GO:0051920);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K11188|4.3377e-162|ptr:738041|PRDX6; peroxiredoxin-6; K11188 peroxiredoxin 6, 1-Cys peroxiredoxin [EC:1.11.1.7 1.11.1.15 3.1.1.-] (A)"	Phenylalanine metabolism (ko00360)	[O]	"Posttranslational modification, protein turnover, chaperones"	AhpC/TSA family;; C-terminal domain of 1-Cys peroxiredoxin;; Redoxin	Peroxiredoxin-6 GN=PRDX6 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxiredoxin-6 [Orycteropus afer afer]
ENSG00000117593(DARS2)	--	37.9055	2412	35.4244	2227	39.737	2475	33.7827	2147	31.2926	1979	28.5169	1814	0.973989035	-0.198605786	normal	0.973893223	-0.191618371	normal	0.55731986	-0.456218542	normal	0.088626059	-0.281763231	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01876|0|hsa:55157|DARS2, ASPRS, LBSL, MT-ASPRS; aspartyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.12); K01876 aspartyl-tRNA synthetase [EC:6.1.1.12] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class II (D, K and N);; GAD domain;; OB-fold nucleic acid binding domain"	"Aspartate--tRNA ligase, mitochondrial (Precursor) GN=DARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: aspartate--tRNA ligase, mitochondrial [Ceratotherium simum simum]"
ENSG00000117594(HSD11B1)	--	0	0	0	0	0	0	0.079113318	1	0	0	0.114724025	3	--	--	--	--	--	--	--	--	--	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K15680|0|hsa:3290|HSD11B1, 11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1; hydroxysteroid (11-beta) dehydrogenase 1 (EC:1.1.1.146); K15680 corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:1.1.1.146] (A)"	Steroid hormone biosynthesis (ko00140);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Corticosteroid 11-beta-dehydrogenase isozyme 1 GN=HSD11B1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 1 [Orycteropus afer afer]
ENSG00000117595(IRF6)	--	0.02617075	2	0	0	0	0	0.113521123	2	0.0254145	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: regulatory region DNA binding (GO:0000975);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10154|0|ptr:457701|IRF6; interferon regulatory factor 6; K10154 interferon regulatory factor 6 (A)	--	--	--	Interferon-regulatory factor 3;; Interferon regulatory factor transcription factor	Interferon regulatory factor 6 GN=IRF6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: interferon regulatory factor 6 [Camelus ferus] 
ENSG00000117597(DIEXF)	--	6.035867804	874	6.67979247	966	6.333156219	905	7.06040043	1034	6.273336271	928	7.395669023	1036	0.953786874	0.211356844	normal	0.975970948	-0.07919843	normal	0.961583012	0.186451459	normal	0.653756557	0.10591205	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K14774|0|hsa:27042|DIEXF, C1orf107, DEF, DJ434O14.5, UTP25; digestive organ expansion factor homolog (zebrafish); K14774 U3 small nucleolar RNA-associated protein 25 (A)"	--	[S]	Function unknown	Protein of unknown function (DUF1253)	Digestive organ expansion factor homolog GN=DIEXF OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: digestive organ expansion factor homolog isoform X2 [Camelus bactrianus]
ENSG00000117601(SERPINC1)	--	0.072073163	1	0	0	0.071131412	0	0.0343176	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K03911|0|hsa:462|SERPINC1, AT3, AT3D, ATIII, THPH7; serpin peptidase inhibitor, clade C (antithrombin), member 1; K03911 antithrombin III (A)"	Complement and coagulation cascades (ko04610)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Antithrombin-III (Precursor) GN=SERPINC1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: antithrombin-III [Tupaia chinensis] 
ENSG00000117602(RCAN3)	--	8.301385923	648	6.522590153	520	9.105197996	613	7.38883469	575	6.694809945	512	5.944964097	456	0.949286105	-0.202753373	normal	0.970539883	-0.043666388	normal	0.629171601	-0.433898903	normal	0.308822779	-0.228711854	normal	--	--	Biological Process: calcium-mediated signaling (GO:0019722);; 	"K17905|3.79277e-147|ptr:456631|RCAN3, DSCR1L2; RCAN family member 3; K17905 calcipression-3 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	Calcipressin	Calcipressin-3 GN=RCAN3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: calcipressin-3 isoform 1 [Trichechus manatus latirostris]
ENSG00000117614(SYF2)	--	18.129928	454	19.6605	488	18.48463056	464	21.121905	532	20.372949	504	21.845712	545	0.9485144	0.197284451	normal	0.970688982	0.025039674	normal	0.939871485	0.223168181	normal	0.577046864	0.14805704	normal	--	--	--	K12868|1.06129e-140|pon:100442603|SYF2; SYF2 pre-mRNA-splicing factor; K12868 pre-mRNA-splicing factor SYF2 (A)	Spliceosome (ko03040)	[DA]	"Cell cycle control, cell division, chromosome partitioning;; RNA processing and modification"	SYF2 splicing factor	Pre-mRNA-splicing factor SYF2 GN=SYF2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pre-mRNA-splicing factor SYF2 [Tupaia chinensis] 
ENSG00000117616(RSRP1)	--	9.039808001	359	12.9911616	542	10.93548257	418	11.409986	411	14.30986826	602	18.7395	651	0.955160002	0.163667305	normal	0.964256052	0.129700588	normal	0.059004502	0.629025111	normal	0.479077091	0.315191815	normal	--	--	--	--	--	--	--	--	Arginine/serine-rich protein 1 GN=RSRP1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: arginine/serine-rich protein 1 [Galeopterus variegatus]
ENSG00000117620(SLC35A3)	--	37.82112685	1490	40.31732727	1681	36.15339289	1424	32.68460138	1362	31.24458194	1297	33.96078354	1413	0.973266116	-0.160244978	normal	0.763183926	-0.395161826	normal	0.98337629	-0.019458378	normal	0.29467277	-0.195645103	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15272|0|pps:100971182|SLC35A3; solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3; K15272 solute carrier family 35 (UDP-sugar transporter), member A1/2/3 (A)"	--	[G]	Carbohydrate transport and metabolism	Nucleotide-sugar transporter;; UAA transporter family;; EamA-like transporter family;; Triose-phosphate Transporter family	UDP-N-acetylglucosamine transporter GN=SLC35A3 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-N-acetylglucosamine transporter isoform X2 [Ursus maritimus]
ENSG00000117625(RCOR3)	--	8.048547606	423	7.528406013	392	6.779286777	393	9.693881005	532	10.7492912	558	9.943300607	561	0.892420047	0.298966311	normal	0.472202203	0.486404697	normal	0.392847819	0.50354997	normal	0.031106247	0.429658214	normal	--	--	--	--	--	[K]	Transcription	Myb-like DNA-binding domain;; ELM2 domain;; Myb-like DNA-binding domain	REST corepressor 3 GN=RCOR3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: REST corepressor 3 isoform 1 [Ceratotherium simum simum]
ENSG00000117632(STMN1)	--	110.553766	2523	101.9605663	2340	108.959384	2481	121.932771	2864	120.8175613	2762	106.433271	2447	0.983175664	0.151972122	normal	0.971787043	0.217648642	normal	0.988519101	-0.028181779	normal	0.589030441	0.11495228	normal	--	--	Biological Process: regulation of microtubule polymerization or depolymerization (GO:0031110);; 	"K04381|2.22762e-121|hsa:3925|STMN1, C1orf215, LAP18, Lag, OP18, PP17, PP19, PR22, SMN; stathmin 1; K04381 stathmin (A)"	MAPK signaling pathway (ko04010);; MicroRNAs in cancer (ko05206)	--	--	Stathmin family	Stathmin GN=STMN1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	"Stathmin, partial [Bos mutus]"
ENSG00000117640(MTFR1L)	--	14.36742418	516	14.82864231	498	17.86773567	538	12.32799934	438	13.22914431	487	11.62004386	418	0.917105049	-0.266410259	normal	0.969614432	-0.053486276	normal	0.796129212	-0.371207626	normal	0.32993635	-0.229810193	normal	--	--	--	--	--	--	--	Mitochondrial fission regulator	Mitochondrial fission regulator 1-like GN=MTFR1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mitochondrial fission regulator 1-like isoform X1 [Ailuropoda melanoleuca] 
ENSG00000117643(MAN1C1)	--	0.82771243	43	0.599967394	36	0.453240073	29	0.695769314	43	0.946428587	56	1.5204616	79	0.980944979	-0.029768611	normal	0.904939259	0.595794017	normal	0.0053265	1.39181052	up	0.18406458	0.700991119	normal	--	--	"Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: membrane (GO:0016020);; "	"K01230|0|ggo:101142550|MAN1C1; mannosyl-oligosaccharide 1,2-alpha-mannosidase IC; K01230 mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 47	"Mannosyl-oligosaccharide 1,2-alpha-mannosidase IC GN=MAN1C1 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IC [Galeopterus variegatus]"
ENSG00000117650(NEK2)	--	21.28288	796	19.81059	756	19.52012	710	18.891128	712	17.74645	650	17.79146	652	0.955884532	-0.191332691	normal	0.937060007	-0.238857205	normal	0.966974333	-0.130947346	normal	0.385822511	-0.189162163	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08857|0|pps:100977113|NEK2; NIMA-related kinase 2; K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)	--	[V]	Defense mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase Nek2 GN=NEK2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase Nek2 [Pteropus alecto] 
ENSG00000117676(RPS6KA1)	--	9.593901725	619	8.454906075	585	8.994755835	625	9.4095949	625	9.11224799	618	8.978491825	591	0.973934209	-0.016873803	normal	0.971617655	0.057598781	normal	0.97033821	-0.088768586	normal	0.966005434	-0.017328588	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K04373|0|hsa:6195|RPS6KA1, HU-1, MAPKAPK1A, RSK, RSK1, p90Rsk; ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1); K04373 p90 ribosomal S6 kinase [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; Oocyte meiosis (ko04114);; mTOR signaling pathway (ko04150);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Progesterone-mediated oocyte maturation (ko04914)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family;; Protein kinase C terminal domain;; Phosphotransferase enzyme family;; PhoP regulatory network protein YrbL	Ribosomal protein S6 kinase alpha-1 GN=RPS6KA1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ribosomal protein S6 kinase alpha-1 isoform X1 [Camelus ferus] 
ENSG00000117682(DHDDS)	--	8.578317	343	9.78848675	369	9.323522072	337	8.235033462	324	13.32285193	432	9.778608282	361	0.96243252	-0.112528281	normal	0.94392699	0.205206037	normal	0.965012372	0.090566067	normal	0.848276962	0.069740305	normal	[I]	Lipid transport and metabolism	"Molecular Function: transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765);; "	"K11778|0|pps:100972313|DHDDS; dehydrodolichyl diphosphate synthase; K11778 ditrans,polycis-polyprenyl diphosphate synthase [EC:2.5.1.87] (A)"	Terpenoid backbone biosynthesis (ko00900)	[I]	Lipid transport and metabolism	Putative undecaprenyl diphosphate synthase	Dehydrodolichyl diphosphate syntase complex subunit DHDDS {ECO:0000305} GN=DHDDS OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: dehydrodolichyl diphosphate synthase isoform X2 [Camelus ferus] 
ENSG00000117691(NENF)	--	56.37153	898	62.5018	1023	51.46561	850	53.17762	871	54.39968	862	59.06734	952	0.975861901	-0.074745126	normal	0.927054174	-0.268040657	normal	0.96707744	0.154946677	normal	0.80267802	-0.066662684	normal	--	--	--	--	--	[R]	General function prediction only	Cytochrome b5-like Heme/Steroid binding domain	Neudesin (Precursor) GN=NENF OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: neudesin [Chrysochloris asiatica]
ENSG00000117697(NSL1)	--	20.02193333	591	20.11864458	584	21.77900022	639	19.8608198	544	18.87202358	499	19.75514629	539	0.961437057	-0.149977178	normal	0.928940617	-0.247660477	normal	0.927106876	-0.253168886	normal	0.332467214	-0.218523649	normal	--	--	Biological Process: mitotic sister chromatid segregation (GO:0000070);; Cellular Component: kinetochore (GO:0000776);; 	"K11545|0|pps:100969849|NSL1; NSL1, MIS12 kinetochore complex component; K11545 kinetochore-associated protein NSL1 (A)"	--	--	--	Kinetochore protein Mis14 like	Kinetochore-associated protein NSL1 homolog GN=NSL1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: kinetochore-associated protein NSL1 homolog [Galeopterus variegatus]
ENSG00000117707(PROX1)	--	0.045529561	6	0.149016162	5	0.56844521	4	0.121464207	16	0.269583638	36	0.271956817	36	--	--	--	0.001379917	2.507621678	up	0.000359331	2.759653454	up	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	Homeo-prospero domain	Prospero homeobox protein 1 GN=PROX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: prospero homeobox protein 1 [Chrysochloris asiatica]
ENSG00000117713(ARID1A)	--	12.2796788	2244	13.53163578	2465	12.64392372	2321	10.965564	2003	10.96213085	2026	10.884928	2036	0.973587056	-0.194601386	normal	0.929503496	-0.304173815	normal	0.973529187	-0.197163135	normal	0.177252934	-0.234195515	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K11653|0|hsa:8289|ARID1A, B120, BAF250, BAF250a, BM029, C1orf4, ELD, MRD14, OSA1, P270, SMARCF1, hELD, hOSA1; AT rich interactive domain 1A (SWI-like); K11653 AT-rich interactive domain-containing protein 1 (A)"	--	[B]	Chromatin structure and dynamics	Domain of unknown function (DUF3518);; ARID/BRIGHT DNA binding domain	AT-rich interactive domain-containing protein 1A GN=ARID1A OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	hypothetical protein PANDA_001156 [Ailuropoda melanoleuca]
ENSG00000117724(CENPF)	--	26.57265947	7025	29.84871052	7907	30.16499576	7900	26.06257272	6887	23.3079255	6215	27.75579493	7407	0.994588219	-0.059441681	normal	0.923089844	-0.368722832	normal	0.994194641	-0.10123474	normal	0.391088147	-0.175742373	normal	--	--	Molecular Function: transcription factor binding (GO:0008134);; Molecular Function: protein homodimerization activity (GO:0042803);; Molecular Function: dynein complex binding (GO:0070840);; 	"K11499|0|hsa:1063|CENPF, CENF, PRO1779, hcp-1; centromere protein F, 350/400kDa; K11499 centromere protein F (A)"	--	--	--	Cenp-F N-terminal domain;; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1;; Rb-binding domain of kinetochore protein Cenp-F/LEK1	Centromere protein F (Precursor) GN=CENPF OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: centromere protein F [Ceratotherium simum simum]
ENSG00000117748(RPA2)	--	20.69365645	647	19.04500928	578	19.98070464	645	22.76130853	734	19.89900867	636	17.37229611	555	0.963784976	0.150845628	normal	0.966775415	0.116240709	normal	0.941248288	-0.224534727	normal	0.957360601	0.019892932	normal	[L]	"Replication, recombination and repair"	--	"K10739|0|pps:100983945|RPA2; replication protein A2, 32kDa; K10739 replication factor A2 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	Replication protein A C terminal;; OB-fold nucleic acid binding domain	Replication protein A 32 kDa subunit GN=RPA2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: replication protein A 32 kDa subunit [Balaenoptera acutorostrata scammoni]
ENSG00000117751(PPP1R8)	--	14.674094	619	16.71926548	730	15.851371	683	16.35403532	706	16.44973789	705	16.690884	663	0.961760104	0.158527891	normal	0.97294638	-0.071548925	normal	0.973934583	-0.051053411	normal	0.985612711	0.008143684	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13216|0|bta:282319|PPP1R8; protein phosphatase 1, regulatory subunit 8; K13216 nuclear inhibitor of protein phosphatase 1 [EC:3.1.4.-] (A)"	--	[R]	General function prediction only	FHA domain	Activator of RNA decay GN=PPP1R8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	nuclear inhibitor of protein phosphatase 1 [Bos taurus] 
ENSG00000117758(STX12)	--	7.720350203	350	7.894157603	327	7.705245875	341	12.83406101	589	12.78836665	522	11.0079386	470	0.011972957	0.717626998	normal	0.059708602	0.650929769	normal	0.60153058	0.45287978	normal	0.001322973	0.613245439	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K13813|3.84448e-160|ptr:456678|STX12; syntaxin 12; K13813 syntaxin 12/13 (A)	Phagosome (ko04145)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Syntaxin-like protein;; SNARE domain;; Syntaxin	Syntaxin-12 GN=STX12 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-12 [Pteropus alecto] 
ENSG00000117791(MARC2)	--	10.10065909	293	8.525720469	238	8.487363072	245	10.2079618	274	12.021188	289	9.769622521	278	0.960112966	-0.126868877	normal	0.925453351	0.257196365	normal	0.952694595	0.173008566	normal	0.80458614	0.094834056	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: molybdenum ion binding (GO:0030151);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	--	--	[R]	General function prediction only	MOSC N-terminal beta barrel domain;; MOSC domain	Mitochondrial amidoxime reducing component 2 (Precursor) GN=MARC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"PREDICTED: mitochondrial amidoxime reducing component 2, partial [Equus przewalskii]"
ENSG00000117834(SLC5A9)	--	0.016411391	1	0.016204119	1	0	0	0.032817207	2	0	0	0.016305712	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14389|0|ptr:743632|SLC5A9; solute carrier family 5 (sodium/sugar cotransporter), member 9; K14389 solute carrier family 5 (sodium/glucose cotransporter), member 9 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium/glucose cotransporter 4 GN=SLC5A9 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/glucose cotransporter 4 isoform 1 [Ceratotherium simum simum]
ENSG00000117859(OSBPL9)	--	34.04355601	1710	32.44206162	1664	34.766828	1655	33.63357839	1643	31.87906911	1618	41.56064637	2075	0.98277869	-0.088415053	normal	0.983458929	-0.06181341	normal	0.907372721	0.317728866	normal	0.805055556	0.06494867	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Oxysterol-binding protein;; PH domain;; Pleckstrin homology domain;; Pleckstrin homology domain	Oxysterol-binding protein-related protein 9 GN=OSBPL9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 9 isoform 2 [Dasypus novemcinctus]
ENSG00000117862(TXNDC12)	--	50.955211	1361	44.889154	1176	50.88698375	1356	63.61298412	1652	56.45221505	1490	54.73179306	1465	0.949307946	0.248459462	normal	0.893791755	0.319631811	normal	0.97975125	0.103141354	normal	0.218105957	0.221516956	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	K05360|1.23656e-124|ptr:100610643|TXNDC12; thioredoxin domain containing 12 (endoplasmic reticulum); K05360 protein-disulfide reductase (glutathione) [EC:1.8.4.2] (A)	Glutathione metabolism (ko00480)	--	--	Thioredoxin-like;; Thioredoxin	Thioredoxin domain-containing protein 12 (Precursor) GN=TXNDC12 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin domain-containing protein 12 [Physeter catodon] 
ENSG00000117868(ESYT2)	--	38.71658808	3627	42.153684	3814	37.88437847	3519	35.69434565	3345	32.48582489	3082	34.19546284	3234	0.98643684	-0.147537692	normal	0.927068888	-0.328719235	normal	0.987389187	-0.130078945	normal	0.266307765	-0.203434774	normal	[R]	General function prediction only	Molecular Function: lipid binding (GO:0008289);; 	--	--	[R]	General function prediction only	C2 domain	Extended synaptotagmin-2 GN=ESYT2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: extended synaptotagmin-2 [Odobenus rosmarus divergens]
ENSG00000117877(CD3EAP)	--	4.660152	284	4.594117	295	4.5303492	259	6.912266	422	5.034212	298	3.465465	217	0.335262898	0.538117775	normal	0.96677768	-0.006794527	normal	0.926406917	-0.261875696	normal	0.814970207	0.137669381	normal	--	--	--	--	--	--	--	DNA-directed RNA polymerase I subunit RPA34.5	DNA-directed RNA polymerase I subunit RPA34 GN=CD3EAP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase I subunit RPA34 [Vicugna pacos]
ENSG00000117899(MESDC2)	--	23.181321	1533	23.155886	1568	22.22247823	1577	28.55884	1954	25.73268273	1735	26.38559	1828	0.902800064	0.31895679	normal	0.97951747	0.12446939	normal	0.967369563	0.204609571	normal	0.225353431	0.216581661	normal	--	--	Biological Process: protein folding (GO:0006457);; 	--	--	[R]	General function prediction only	Chaperone for wingless signalling and trafficking of LDL receptor	LDLR chaperone MESD (Precursor) GN=MESDC2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LDLR chaperone MESD [Oryctolagus cuniculus]
ENSG00000117906(RCN2)	--	91.669929	2029	88.75501	2027	92.9472	2174	90.41298	2090	89.20319	2023	96.250419	2123	0.987108168	0.011892941	normal	0.9864991	-0.024258211	normal	0.987080455	-0.042509087	normal	0.950458395	-0.019641263	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair	Reticulocalbin-2 (Precursor) GN=RCN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: reticulocalbin-2 isoform 2 [Dasypus novemcinctus]
ENSG00000117971(CHRNB4)	--	0.609063094	31	0.1921036	9	0.151889103	6	0.534104239	18	1.1028083	43	0.353823061	14	0.940461304	-0.764779865	normal	0.00341763	2.062606097	up	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04815|0|hsa:1143|CHRNB4; cholinergic receptor, nicotinic, beta 4 (neuronal); K04815 nicotinic acetylcholine receptor beta-4 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Neuronal acetylcholine receptor subunit beta-4 (Precursor) GN=CHRNB4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit beta-4 [Sus scrofa]
ENSG00000117983(MUC5B)	--	0.21621241	46	0.31814872	53	0.077710825	34	0.668707028	290	1.477525246	661	1.779981526	339	0	2.586316767	up	0	3.582188912	up	0	3.253220146	up	0.000429076	3.256778712	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13908|0|hsa:727897|MUC5B, MG1, MUC-5B, MUC5, MUC9; mucin 5B, oligomeric mucus/gel-forming; K13908 mucin-5B (A)"	Salivary secretion (ko04970)	[WV]	Extracellular structures;; Defense mechanisms	Mucin-2 protein WxxW repeating region;; von Willebrand factor type D domain;; C8 domain;; Trypsin Inhibitor like cysteine rich domain;; von Willebrand factor type C domain	Mucin-5B (Precursor) GN=MUC5B OS=Homo sapiens (Human) PE=1 SV=3	VW	Defense mechanisms;; Extracellular structures	PREDICTED: mucin-5B-like [Galeopterus variegatus]
ENSG00000117984(CTSD)	--	374.8845229	13917	396.8511002	14888	358.9676491	13596	276.9288594	10198	291.8699068	10766	430.5944177	16014	0.702041541	-0.479332171	normal	0.694889425	-0.489035494	normal	0.991819213	0.227836627	normal	0.538480907	-0.217385565	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Biological Process: proteolysis (GO:0006508);; 	"K01379|0|hsa:1509|CTSD, CLN10, CPSD, HEL-S-130P; cathepsin D (EC:3.4.23.5); K01379 cathepsin D [EC:3.4.23.5] (A)"	Sphingolipid signaling pathway (ko04071);; Lysosome (ko04142);; Tuberculosis (ko05152)	[O]	"Posttranslational modification, protein turnover, chaperones"	Eukaryotic aspartyl protease;; A1 Propeptide;; Xylanase inhibitor N-terminal;; Xylanase inhibitor C-terminal	Cathepsin D heavy chain (Precursor) GN=CTSD OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin D [Eptesicus fuscus]
ENSG00000118004(COLEC11)	--	0.319091129	8	0.13410045	4	0.160798546	3	0.10216867	3	0.300281768	6	0.10346388	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K10066|1.67932e-169|pps:100974149|COLEC11; collectin sub-family member 11; K10066 collectin sub-family member 11 (A)	Phagosome (ko04145)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; Collagen triple helix repeat (20 copies)	Collectin-11 (Precursor) GN=COLEC11 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: collectin-11 isoform X2 [Oryctolagus cuniculus]
ENSG00000118007(STAG1)	--	6.002374	583	7.051930756	701	6.09342966	625	8.748021116	953	8.73661282	872	8.760252029	945	0.014726056	0.676740342	normal	0.904129077	0.292919588	normal	0.093406589	0.587003618	normal	0.001542553	0.515729596	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	K06671|0|ptr:460717|STAG1; stromal antigen 1; K06671 cohesin complex subunit SA-1/2 (A)	Cell cycle (ko04110)	[D]	"Cell cycle control, cell division, chromosome partitioning"	STAG domain	Cohesin subunit SA-1 GN=STAG1 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cohesin subunit SA-1 [Canis lupus familiaris]
ENSG00000118017(A4GNT)	--	0.515479	15	0.376218	11	0.475636	13	0.204701	6	0.167885	4	0.23929	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08251|0|hsa:51146|A4GNT, alpha4GnT; alpha-1,4-N-acetylglucosaminyltransferase; K08251 alpha 1,4-N-acetylglucosaminyltransferase [EC:2.4.1.-] (A)"	--	[G]	Carbohydrate transport and metabolism	"Alpha 1,4-glycosyltransferase conserved region;; Glycosyltransferase sugar-binding region containing DXD motif"	"Alpha-1,4-N-acetylglucosaminyltransferase GN=A4GNT OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-1,4-N-acetylglucosaminyltransferase [Trichechus manatus latirostris]"
ENSG00000118046(STK11)	--	24.481224	1373	22.34926515	1294	23.60589325	1387	23.467264	1327	22.674064	1294	20.3306302	1154	0.980754288	-0.079904557	normal	0.981903178	-0.021401546	normal	0.930979538	-0.273288844	normal	0.566043028	-0.124369868	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07298|0|hsa:6794|STK11, LKB1, PJS, hLKB1; serine/threonine kinase 11 (EC:2.7.11.1); K07298 serine/threonine-protein kinase 11 (A)"	FoxO signaling pathway (ko04068);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adipocytokine signaling pathway (ko04920)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase STK11 (Precursor) GN=STK11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase STK11 [Myotis davidii] 
ENSG00000118058(KMT2A)	--	6.880410966	2220	7.184002372	2357	7.676827088	2409	7.155839524	2375	7.201206079	2430	6.676711804	2273	0.987015322	0.06649108	normal	0.988019866	0.02256374	normal	0.986124731	-0.09206864	normal	0.997736687	-0.002338932	normal	[R]	General function prediction only	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; 	"K09186|0|hsa:4297|KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1, MLL1A, TET1-MLL, TRX1, WDSTS; lysine (K)-specific methyltransferase 2A (EC:2.1.1.43); K09186 histone-lysine N-methyltransferase MLL1 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	SET domain;; F/Y rich C-terminus;; F/Y-rich N-terminus;; PHD-finger;; PHD-like zinc-binding domain;; CXXC zinc finger domain;; PHD-zinc-finger like domain	MLL cleavage product C180 GN=KMT2A OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: histone-lysine N-methyltransferase MLL [Ceratotherium simum simum]
ENSG00000118094(TREH)	--	0.608559766	31	0.503882221	26	0.647242742	33	1.03617	53	0.918126922	46	0.680202244	35	0.863453787	0.715493545	normal	0.863647045	0.7677279	normal	0.983090465	0.073333883	normal	0.380453693	0.552145426	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: alpha,alpha-trehalase activity (GO:0004555);; Biological Process: trehalose metabolic process (GO:0005991);; "	"K01194|0|pps:100972724|TREH; trehalase (brush-border membrane glycoprotein); K01194 alpha,alpha-trehalase [EC:3.2.1.28] (A)"	Starch and sucrose metabolism (ko00500)	[G]	Carbohydrate transport and metabolism	Trehalase;; Mannosyl oligosaccharide glucosidase	Trehalase (Precursor) GN=TREH OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: trehalase-like [Ceratotherium simum simum]
ENSG00000118096(IFT46)	--	8.417856918	272	7.286328224	234	9.17279883	290	12.045696	333	13.62423441	392	11.29234187	361	0.923221395	0.25975542	normal	0.030293498	0.719289752	normal	0.892123752	0.306220559	normal	0.072157262	0.427577018	normal	--	--	Biological Process: intraciliary transport (GO:0042073);; 	--	--	--	--	Intraflagellar transport complex B protein 46 C terminal	Intraflagellar transport protein 46 homolog GN=IFT46 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: intraflagellar transport protein 46 homolog isoform X1 [Orycteropus afer afer]
ENSG00000118137(APOA1)	--	0.075557995	1	0.293100632	4	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K08757|7.46354e-170|ptr:451564|APOA1, Apo-AI, ApoA-I; apolipoprotein A-I; K08757 apolipoprotein A-I (A)"	PPAR signaling pathway (ko03320);; Fat digestion and absorption (ko04975);; Vitamin digestion and absorption (ko04977);; African trypanosomiasis (ko05143)	--	--	Apolipoprotein A1/A4/E domain;; Apolipoprotein C-I (ApoC-1);; YtxH-like protein;; Protein of unknown function (DUF3618)	Truncated apolipoprotein A-I (Precursor) GN=APOA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: apolipoprotein A-I [Canis lupus familiaris]
ENSG00000118156(ZNF541)	--	0	0	0	0	0	0	0	0	0	0	0.017429878	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[K]	Transcription	"ELM2 domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 541 GN=ZNF541 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 541 isoform X1 [Canis lupus familiaris] 
ENSG00000118160(SLC8A2)	--	0.371031963	7	0.038529544	3	0.077051592	5	0.035725722	3	0.092365971	6	0.080806528	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell communication (GO:0007154);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K05849|0|hsa:6543|SLC8A2, NCX2; solute carrier family 8 (sodium/calcium exchanger), member 2; K05849 solute carrier family 8 (sodium/calcium exchanger) (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Protein digestion and absorption (ko04974)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Calx-beta domain;; Sodium/calcium exchanger protein	Sodium/calcium exchanger 2 (Precursor) GN=SLC8A2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/calcium exchanger 2 isoformX2 [Canis lupus familiaris] 
ENSG00000118162(KPTN)	--	7.792139766	242	9.102713892	276	10.4980335	288	6.398842133	191	8.023564072	210	7.864562345	232	0.852947058	-0.369618063	normal	0.779975848	-0.413101751	normal	0.889836986	-0.31836905	normal	0.18398382	-0.369002219	normal	--	--	--	--	--	--	--	FG-GAP repeat	Kaptin GN=KPTN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: kaptin isoform X2 [Canis lupus familiaris]
ENSG00000118181(RPS25)	--	338.771	3641	335.969	3643	324.365	3546	382.982	4187	335.858	3611	329.579	3595	0.985525466	0.170682712	normal	0.991080408	-0.034140897	normal	0.991409749	0.01150292	normal	0.842595709	0.051369071	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02975|3.79352e-46|mcf:101864921|uncharacterized LOC101864921; K02975 small subunit ribosomal protein S25e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	S25 ribosomal protein	40S ribosomal protein S25 GN=RPS25 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	hypothetical protein PANDA_019879 [Ailuropoda melanoleuca]
ENSG00000118193(KIF14)	--	10.20705	1422	9.09023	1247	10.70075	1439	9.68259	1342	8.217785	1147	8.669358694	1217	0.978502277	-0.114241966	normal	0.973023908	-0.141843203	normal	0.94565368	-0.249743112	normal	0.388276341	-0.169957072	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K17915|0|hsa:9928|KIF14; kinesin family member 14; K17915 kinesin family member 14 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain;; FHA domain	Kinesin-like protein KIF14 GN=KIF14 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF14 [Galeopterus variegatus]
ENSG00000118194(TNNT2)	--	0.034744714	2	0.21825425	4	0.033657482	1	0.255099912	8	0.084351079	4	0.2185535	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: troponin complex (GO:0005861);; 	"K12045|2.02646e-121|ggo:101151369|TNNT2; troponin T, cardiac muscle isoform 1; K12045 troponin T, cardiac muscle (A)"	Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Troponin	"Troponin T, cardiac muscle GN=TNNT2 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: troponin T, cardiac muscle isoform X6 [Orycteropus afer afer]"
ENSG00000118197(DDX59)	--	9.6721933	386	9.828995297	367	8.614036205	324	5.606314757	231	6.110259148	250	7.134389931	282	0.010742493	-0.76754435	normal	0.273099802	-0.572402015	normal	0.943780687	-0.207550807	normal	0.023160196	-0.518098576	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; HIT zinc finger	Probable ATP-dependent RNA helicase DDX59 GN=DDX59 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX59 [Felis catus] 
ENSG00000118200(CAMSAP2)	--	13.4959398	1908	15.31536427	2138	14.47157836	1955	15.03169845	2134	17.058955	2370	17.86015886	2402	0.981793474	0.130567293	normal	0.98311174	0.127113225	normal	0.938113838	0.288574379	normal	0.334298095	0.181755598	normal	--	--	Molecular Function: calmodulin binding (GO:0005516);; Molecular Function: microtubule binding (GO:0008017);; Molecular Function: spectrin binding (GO:0030507);; Biological Process: neuron projection development (GO:0031175);; 	"K17493|0|hsa:23271|CAMSAP2, CAMSAP1L1; calmodulin regulated spectrin-associated protein family, member 2; K17493 calmodulin-regulated spectrin-associated protein (A)"	--	[Z]	Cytoskeleton	Microtubule-binding calmodulin-regulated spectrin-associated;; Calponin homology (CH) domain;; CAMSAP CH domain	Calmodulin-regulated spectrin-associated protein 2 GN=CAMSAP2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: calmodulin-regulated spectrin-associated protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000118217(ATF6)	--	14.14231497	1093	14.93152691	995	13.37971952	931	15.7010561	1368	16.29220701	1368	16.22024098	1298	0.915094547	0.292574327	normal	0.614776726	0.43730424	normal	0.457874393	0.47049574	normal	0.012053717	0.39662914	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09054|0|hsa:22926|ATF6, ATF6A; activating transcription factor 6; K09054 cyclic AMP-dependent transcription factor ATF-6 alpha (A)"	Protein processing in endoplasmic reticulum (ko04141);; Alzheimer's disease (ko05010)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper	Processed cyclic AMP-dependent transcription factor ATF-6 alpha GN=ATF6 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: cyclic AMP-dependent transcription factor ATF-6 alpha [Bos mutus]
ENSG00000118246(FASTKD2)	--	22.61032142	1168	21.23136688	1124	23.3874312	1188	13.57123125	773	15.69405554	868	12.92092182	726	0.037833161	-0.625313198	normal	0.747610866	-0.393697017	normal	0.004425875	-0.717604207	normal	0.000139384	-0.577246679	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; 	"K18190|0|hsa:22868|FASTKD2, KIAA0971; FAST kinase domains 2; K18190 FAST kinase domain-containing protein 2 (A)"	--	--	--	"FAST kinase-like protein, subdomain 1;; FAST kinase-like protein, subdomain 2;; RAP domain"	FAST kinase domain-containing protein 2 GN=FASTKD2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: FAST kinase domain-containing protein 2 [Galeopterus variegatus]
ENSG00000118257(NRP2)	--	38.0762036	4668	26.56904152	3320	35.85237421	4461	45.92650153	5644	48.90153236	6094	37.35375132	4612	0.97828637	0.243008339	normal	6.90E-05	0.854488201	normal	0.99264835	0.039720679	normal	0.135617764	0.37185536	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K06819|0|mcf:102121366|NRP2; neuropilin 2; K06819 neuropilin 2 (A)	--	--	--	CUB domain;; F5/8 type C domain;; MAM domain;; Domain of unknown function (DUF3481)	Neuropilin-2 (Precursor) GN=NRP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuropilin-2 isoform X1 [Camelus ferus]
ENSG00000118260(CREB1)	--	11.327666	923	14.007767	947	12.87686	927	10.31367043	854	8.3432887	738	9.726679193	784	0.968802051	-0.142679833	normal	0.775976564	-0.380479912	normal	0.935356863	-0.249563867	normal	0.172227103	-0.256871741	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K05870|0|umr:103659802|CREB1; cAMP responsive element binding protein 1; K05870 cyclic AMP-responsive element-binding protein 1 (A)	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Osteoclast differentiation (ko04380);; Antigen processing and presentation (ko04612);; TNF signaling pathway (ko04668);; Circadian rhythm (ko04710);; Circadian entrainment (ko04713);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	[K]	Transcription	pKID domain;; bZIP transcription factor;; Basic region leucine zipper	Cyclic AMP-responsive element-binding protein 1 GN=CREB1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	Cyclic AMP-responsive element-binding protein 1 [Myotis davidii]
ENSG00000118263(KLF7)	--	8.121469	855	8.556528637	980	10.13085295	953	9.317854224	1121	9.059025621	1085	11.36798794	1206	0.81768672	0.359392223	normal	0.972956812	0.125231116	normal	0.868626345	0.330922513	normal	0.129983792	0.270436642	normal	[R]	General function prediction only	--	K09207|0|ptr:459900|KLF7; Kruppel-like factor 7 (ubiquitous); K09207 krueppel-like factor 6/7 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 7 GN=KLF7 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: Krueppel-like factor 7 isoform X1 [Elephantulus edwardii]
ENSG00000118271(TTR)	--	0	0	0	0	0	0	0	0	0.185017039	0	0.14597	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	HIUase/Transthyretin family	Transthyretin (Precursor) GN=TTR OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: transthyretin [Ceratotherium simum simum]
ENSG00000118276(B4GALT6)	--	10.35415405	734	11.42017496	667	11.04396541	757	8.296049361	597	7.053434229	500	6.71812024	493	0.86078339	-0.328118205	normal	0.62614958	-0.436039046	normal	0.053287292	-0.62543668	normal	0.009266599	-0.462334521	normal	--	--	--	"K07553|0|pon:100455489|B4GALT6; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6; K07553 beta-1,4-galactosyltransferase 6 [EC:2.4.1.274] (A)"	Sphingolipid metabolism (ko00600)	[G]	Carbohydrate transport and metabolism	N-terminal region of glycosyl transferase group 7;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	"Glucosylceramide beta-1,4-galactosyltransferase GN=B4GALT6 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-galactosyltransferase 6 isoform X1 [Condylura cristata]"
ENSG00000118292(C1orf54)	--	0.289991211	5	0.146742009	3	0.239646006	4	0.682558	14	0.5708901	12	0.337045	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4634)	Uncharacterized protein C1orf54 (Precursor) GN=C1orf54 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf54 homolog isoform X2 [Loxodonta africana]
ENSG00000118298(CA14)	--	0.06641629	3	0	0	0	0	0.044253709	2	0.161600251	1	0.02179062	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	"K01672|0|hsa:23632|CA14, CAXiV; carbonic anhydrase XIV (EC:4.2.1.1); K01672 carbonic anhydrase [EC:4.2.1.1] (A)"	Nitrogen metabolism (ko00910)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase 14 (Precursor) GN=CA14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carbonic anhydrase 14 [Loxodonta africana]
ENSG00000118307(CASC1)	--	0.25229604	12	0.12118052	5	0.219825333	9	0.186119934	9	0.182923437	8	0.12454122	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K17580|0|ptr:465348|CASC1; cancer susceptibility candidate 1; K17580 cancer susceptibility candidate protein 1 (A)	--	--	--	Cancer susceptibility candidate 1	Protein CASC1 GN=CASC1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein CASC1 isoform X2 [Tupaia chinensis]
ENSG00000118322(ATP10B)	--	0	0	0.0123844	2	0.02153604	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	--	--	[R]	General function prediction only	haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase VB GN=ATP10B OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase VB [Equus przewalskii]
ENSG00000118363(SPCS2)	--	62.1077854	1709	65.52409255	2008	61.3630576	1819	66.18821704	2034	63.8301946	1834	72.36791627	2094	0.964928364	0.220153424	normal	0.978573515	-0.152072295	normal	0.972187237	0.194673496	normal	0.711914584	0.0857302	normal	--	--	Cellular Component: signal peptidase complex (GO:0005787);; Biological Process: signal peptide processing (GO:0006465);; Molecular Function: peptidase activity (GO:0008233);; Cellular Component: integral component of membrane (GO:0016021);; 	K12947|1.68512e-135|pale:102896250|SPCS2; signal peptidase complex subunit 2 homolog (S. cerevisiae); K12947 signal peptidase complex subunit 2 [EC:3.4.-.-] (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Microsomal signal peptidase 25 kDa subunit (SPC25)	Signal peptidase complex subunit 2 GN=SPCS2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal peptidase complex subunit 2 isoform X1 [Pteropus alecto]
ENSG00000118369(USP35)	--	3.587838293	316	3.308701632	315	3.065604681	311	2.825071227	258	3.270229762	270	2.393200001	230	0.882610741	-0.32165142	normal	0.930499891	-0.242559717	normal	0.704561321	-0.441068447	normal	0.203968466	-0.33502618	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11854|0|hsa:57558|USP35; ubiquitin specific peptidase 35 (EC:3.4.19.12); K11854 ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 35 GN=USP35 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 35 [Odobenus rosmarus divergens]
ENSG00000118402(ELOVL4)	--	3.157443564	136	3.686472	159	3.915205	167	1.957031303	85	1.92244	83	2.838675	125	0.373529489	-0.698820343	normal	0.016585395	-0.94658463	normal	0.842890779	-0.421780957	normal	0.041039381	-0.676842632	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K10249|0|hsa:6785|ELOVL4, ADMD, CT118, ISQMR, SCA34, STGD2, STGD3; ELOVL fatty acid elongase 4 (EC:2.3.1.199); K10249 elongation of very long chain fatty acids protein 4 [EC:2.3.1.199] (A)"	Fatty acid elongation (ko00062)	[I]	Lipid transport and metabolism	GNS1/SUR4 family	Elongation of very long chain fatty acids protein 4 GN=ELOVL4 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: elongation of very long chain fatty acids protein 4-like [Tupaia chinensis]
ENSG00000118407(FILIP1)	--	0.024589715	4	0	0	0	0	0.681863617	92	0.847829	105	1.074870022	137	5.55E-16	4.052193641	up	0	6.127619727	up	0	6.51304218	up	9.02E-27	6.361658485	up	--	--	--	--	--	--	--	Cortactin-binding protein-2	Filamin-A-interacting protein 1 GN=FILIP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: filamin-A-interacting protein 1 isoform X1 [Pteropus alecto] 
ENSG00000118412(CASP8AP2)	--	4.690874457	633	5.632437431	749	5.552267694	726	5.222944	635	4.496428259	607	4.043172	533	0.973977086	-0.026217636	normal	0.869143561	-0.323967642	normal	0.5484863	-0.453019596	normal	0.182062839	-0.269693416	normal	--	--	--	--	--	--	--	--	CASP8-associated protein 2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CASP8-associated protein 2 [Galeopterus variegatus]
ENSG00000118418(HMGN3)	--	35.906253	472	39.444343	531	31.26604	420	45.7701644	615	36.071794	475	39.941416	534	0.829218963	0.349966862	normal	0.952604684	-0.181663532	normal	0.850829075	0.337080129	normal	0.505835035	0.168549058	normal	--	--	Cellular Component: chromatin (GO:0000785);; Cellular Component: nucleus (GO:0005634);; Molecular Function: nucleosomal DNA binding (GO:0031492);; 	K11301|1.76478e-58|mcf:102141951|HMGN3; high mobility group nucleosomal binding domain 3; K11301 high-mobility group nucleosome-binding domain-containing protein 3 (A)	--	--	--	HMG14 and HMG17	High mobility group nucleosome-binding domain-containing protein 3 GN=HMGN3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: high mobility group nucleosome-binding domain-containing protein 3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000118420(UBE3D)	--	4.28016	116	3.620817	108	3.33848	89	2.904989	89	3.38668814	109	3.466971	103	0.899376458	-0.406906618	normal	0.968786396	-0.008017981	normal	0.961441528	0.199324817	normal	0.904901829	-0.077471356	normal	--	--	--	--	--	[S]	Function unknown	HECT-like Ubiquitin-conjugating enzyme (E2)-binding	E3 ubiquitin-protein ligase E3D GN=UBE3D OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase E3D isoform X2 [Equus przewalskii]
ENSG00000118432(CNR1)	--	0.2604564	16	0.5516949	16	0.177974142	16	0.666242766	44	0.524899243	36	1.505360799	84	0.236326998	1.347702662	normal	0.741080185	1.078926285	normal	1.47E-07	2.279904047	up	0.035539487	1.753384409	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04277|0|ptr:472066|CNR1; cannabinoid receptor 1 (brain); K04277 cannabinoid receptor 1 (A)	Rap1 signaling pathway (ko04015);; Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srx	Cannabinoid receptor 1 GN=CNR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cannabinoid receptor 1 isoform X1 [Orycteropus afer afer] 
ENSG00000118454(ANKRD13C)	--	7.3177796	351	6.663044268	381	6.19163	355	7.200504512	384	7.535231971	437	7.132276	419	0.964504048	0.098391182	normal	0.952145224	0.175763918	normal	0.935704264	0.229937208	normal	0.551497785	0.169033353	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	GPCR-chaperone;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 13C GN=ANKRD13C OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 13C [Tupaia chinensis]
ENSG00000118473(SGIP1)	--	0.018426342	1	0	0	0	0	0.036708398	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Muniscin C-terminal mu homology domain;; Adaptor complexes medium subunit family	SH3-containing GRB2-like protein 3-interacting protein 1 GN=SGIP1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: SH3-containing GRB2-like protein 3-interacting protein 1 isoform X1 [Orycteropus afer afer]
ENSG00000118482(PHF3)	--	10.93184105	1513	11.7786144	1581	11.49156228	1558	10.00774058	1407	10.45869252	1505	10.21143628	1535	0.977026858	-0.135479208	normal	0.981212357	-0.092409827	normal	0.984128162	-0.029718957	normal	0.713277133	-0.085924535	normal	--	--	"Biological Process: transcription, DNA-templated (GO:0006351);; "	--	--	[K]	Transcription	"Transcription factor S-II (TFIIS), central domain;; SPOC domain;; PHD-finger"	PHD finger protein 3 GN=PHF3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	hypothetical protein PANDA_015611 [Ailuropoda melanoleuca]
ENSG00000118495(PLAGL1)	--	5.945787446	379	6.353934676	389	5.893958504	342	7.688750439	477	5.658705282	349	7.739008202	449	0.892325402	0.299873621	normal	0.951153456	-0.177241771	normal	0.784023875	0.382945474	normal	0.518057513	0.178209354	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein PLAGL1 GN=PLAGL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein PLAGL1 isoform X1 [Tupaia chinensis] 
ENSG00000118496(FBXO30)	--	6.710544269	844	7.179771953	902	6.744084653	826	6.776258141	864	6.95677	873	7.305335437	918	0.977703996	0.002950741	normal	0.975803806	-0.068455666	normal	0.968457713	0.143811072	normal	0.941204269	0.024700652	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	"K10307|0|hsa:84085|FBXO30, Fbx30; F-box protein 30; K10307 F-box protein 30 (A)"	--	--	--	F-box domain;; TRAF-type zinc finger	F-box only protein 30 GN=FBXO30 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	F-box only protein 30 [Myotis brandtii]
ENSG00000118503(TNFAIP3)	--	6.529444612	562	9.300501	554	4.401255074	369	9.87059777	824	10.61603823	756	13.51354211	1183	0.280636517	0.520061422	normal	0.653092316	0.42607446	normal	0	1.66843064	up	0.025058358	0.8749652	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	"K11859|0|hsa:7128|TNFAIP3, A20, OTUD7C, TNFA1P2; tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12); K11859 tumor necrosis factor, alpha-induced protein 3 [EC:3.4.19.12 6.3.2.19] (A)"	NF-kappa B signaling pathway (ko04064);; NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668);; Measles (ko05162);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	A20-like zinc finger;; OTU-like cysteine protease	A20p37 GN=TNFAIP3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor alpha-induced protein 3 [Tupaia chinensis] 
ENSG00000118507(AKAP7)	--	2.102789618	75	2.17091451	68	2.354659708	88	2.792346729	111	3.02367694	108	1.774740671	77	0.817284826	0.525860982	normal	0.664959736	0.63470727	normal	0.964713569	-0.197308823	normal	0.494575592	0.335939747	normal	--	--	--	K16524|0|mcf:102129801|AKAP7; A kinase (PRKA) anchor protein 7; K16524 A-kinase anchor protein 7 (A)	--	[K]	Transcription	AKAP7 2'5' RNA ligase-like domain	A-kinase anchor protein 7 isoform gamma GN=AKAP7 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	A-kinase anchor protein 7 isoform gamma [Pteropus alecto]
ENSG00000118508(RAB32)	--	25.0667	499	31.7015	651	27.352	560	31.2267	633	25.2982	503	34.5591	696	0.880003036	0.311480274	normal	0.749373948	-0.392485277	normal	0.888335672	0.30462975	normal	0.833277129	0.078319139	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07918|9.29868e-152|ptr:748474|RAB32; RAB32, member RAS oncogene family; K07918 Ras-related protein Rab-32 (A)"	--	[T]	Signal transduction mechanisms	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-32 GN=RAB32 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-32 [Felis catus]
ENSG00000118513(MYB)	--	0.033455765	2	0.094908302	5	0.315941413	12	0.608657153	35	0.444034403	28	0.565529301	30	3.92E-05	3.345480676	up	0.057445384	2.161691248	normal	0.749844563	1.214014047	normal	0.000248821	2.27178581	up	[KAD]	"Transcription;; RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09420|0|ptr:463016|MYB; v-myb avian myeloblastosis viral oncogene homolog; K09420 myb proto-oncogene protein (A)	PI3K-Akt signaling pathway (ko04151);; HTLV-I infection (ko05166)	[K]	Transcription	"C-myb, C-terminal;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain;; LMSTEN motif"	Transcriptional activator Myb GN=MYB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcriptional activator Myb isoform X1 [Galeopterus variegatus]
ENSG00000118514(ALDH8A1)	--	0.068781448	3	0.022393614	1	0.033148591	0	1.115047735	9	0.11178156	4	0.189379469	5	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[C]	Energy production and conversion	Aldehyde dehydrogenase family	Aldehyde dehydrogenase family 8 member A1 GN=ALDH8A1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: aldehyde dehydrogenase family 8 member A1 isoform X1 [Galeopterus variegatus]
ENSG00000118515(SGK1)	--	10.49809767	395	7.967931823	301	8.00008703	301	17.33648316	669	12.63705795	483	14.045347	531	0.007753483	0.72712502	normal	0.059121994	0.658199943	normal	0.002087266	0.807562126	normal	0.002667271	0.733135804	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K13302|0|hsa:6446|SGK1, SGK; serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1); K13302 serum/glucocorticoid-regulated kinase 1 [EC:2.7.11.1] (A)"	FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; Aldosterone-regulated sodium reabsorption (ko04960)	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Protein kinase C terminal domain;; Kinase-like;; PX domain	Serine/threonine-protein kinase Sgk1 GN=SGK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Sgk1 isoform X1 [Galeopterus variegatus]
ENSG00000118518(RNF146)	--	12.84398799	459	14.65690366	556	10.72428302	430	12.36279483	449	13.22505607	493	17.692935	612	0.969037505	-0.062399774	normal	0.949599335	-0.194361968	normal	0.39379004	0.499423902	normal	0.827045882	0.084327425	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K15700|0|cjc:100399544|RNF146; ring finger protein 146; K15700 E3 ubiquitin-protein ligase RNF146 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"WWE domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF146 GN=RNF146 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF146 [Vicugna pacos]
ENSG00000118523(CTGF)	--	7.14436	288	10.6501	431	17.1535	695	21.5619	872	23.8674	963	15.9454	643	2.44E-15	1.562399481	up	3.64E-08	1.135686192	up	0.96819176	-0.120213654	normal	0.083493843	0.788696719	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	"K06827|0|hsa:1490|CTGF, CCN2, HCS24, IGFBP8, NOV2; connective tissue growth factor; K06827 connective tissue growth factor (A)"	Hippo signaling pathway (ko04390)	--	--	Cystine-knot domain;; Insulin-like growth factor binding protein;; von Willebrand factor type C domain;; Thrombospondin type 1 domain	Connective tissue growth factor (Precursor) GN=CTGF OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: connective tissue growth factor [Camelus bactrianus]
ENSG00000118526(TCF21)	--	0.303581379	20	0.3419945	17	0.301300188	15	0.092864508	6	0.124858693	9	0.20699478	16	0.791479127	-1.541412393	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Transcription factor 21 GN=TCF21 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: transcription factor 21 [Loxodonta africana]
ENSG00000118557(PMFBP1)	--	4.5324436	75	4.815648796	74	3.7002194	60	5.2135914	79	3.5306625	58	4.5115108	69	0.973559315	0.043266174	normal	0.945379824	-0.364463617	normal	0.970223697	0.188899449	normal	0.967635723	-0.04297365	normal	--	--	--	--	--	--	--	--	Polyamine-modulated factor 1-binding protein 1 GN=PMFBP1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: polyamine-modulated factor 1-binding protein 1 isoform X1 [Felis catus]
ENSG00000118564(FBXL5)	--	29.06358122	921	20.7300506	800	26.44973791	936	30.28526355	1117	25.688616	1026	28.3115836	1035	0.940201939	0.24714903	normal	0.858142668	0.336968526	normal	0.971317153	0.136549009	normal	0.204884248	0.237057538	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10271|0|hsa:26234|FBXL5, FBL4, FBL5, FLR1; F-box and leucine-rich repeat protein 5; K10271 F-box and leucine-rich repeat protein 5 (A)"	--	--	--	F-box-like;; Hemerythrin HHE cation binding domain;; F-box domain;; Leucine Rich repeats (2 copies);; Leucine Rich repeat;; Leucine rich repeat;; Leucine Rich Repeat	F-box/LRR-repeat protein 5 GN=FBXL5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 5 isoform 1 [Orcinus orca]
ENSG00000118579(MED28)	--	3.331886647	406	3.694528463	442	3.721092	453	3.140120295	389	3.931685035	470	4.285215626	487	0.965673759	-0.092185384	normal	0.968072779	0.066965624	normal	0.966924686	0.095810739	normal	0.946746066	0.028677863	normal	--	--	--	K15141|1.53622e-111|ptr:461133|MED28; mediator complex subunit 28; K15141 mediator of RNA polymerase II transcription subunit 28 (A)	--	--	--	Mediator complex subunit 28	Mediator of RNA polymerase II transcription subunit 28 GN=MED28 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 28 [Ochotona princeps]
ENSG00000118596(SLC16A7)	--	6.148551086	765	4.810704402	681	5.754545441	779	6.495226054	708	5.823789746	598	6.531039765	1076	0.966176805	-0.142245574	normal	0.947774832	-0.208441492	normal	0.515615087	0.45693348	normal	0.902498766	0.078573765	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08184|0|ptr:467047|SLC16A7; solute carrier family 16 (monocarboxylate transporter), member 7; K08184 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 7 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; MFS_1 like family	Monocarboxylate transporter 2 GN=SLC16A7 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 2 [Galeopterus variegatus]
ENSG00000118600(TMEM5)	--	17.113108	540	18.209897	580	17.052573	540	18.22742	580	16.894099	533	15.0050913	476	0.970558829	0.072063373	normal	0.961875066	-0.142954949	normal	0.951251608	-0.189722951	normal	0.777342402	-0.084923918	normal	--	--	--	--	--	--	--	--	Transmembrane protein 5 GN=TMEM5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PANDA_008780 [Ailuropoda melanoleuca]
ENSG00000118620(ZNF430)	--	1.728280798	119	1.2839082	86	1.62930008	97	1.987452249	121	1.50105574	106	1.149508594	82	0.969389215	-0.006700992	normal	0.947940083	0.275853312	normal	0.956973998	-0.246467926	normal	0.994371526	0.010709097	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:80264|ZNF430; zinc finger protein 430; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; SprT-like family;; XPA protein N-terminal;; C1-like domain"	Zinc finger protein 430 GN=ZNF430 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000118640(VAMP8)	--	14.6515	180	15.890423	206	13.398655	174	5.740489265	77	6.8647673	86	6.29034	79	6.30E-05	-1.239224875	down	1.54E-05	-1.266802599	down	0.000556716	-1.132468994	down	2.15E-05	-1.231690614	down	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K08512|1.66527e-49|ptr:459365|VAMP8; vesicle-associated membrane protein 8; K08512 vesicle-associated membrane protein 8 (A)	SNARE interactions in vesicular transport (ko04130);; Platelet activation (ko04611)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Synaptobrevin	Vesicle-associated membrane protein 8 GN=VAMP8 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein 8 [Tupaia chinensis]
ENSG00000118655(DCLRE1B)	--	4.536917	317	4.03662	282	4.562473	316	3.98117	274	4.17625	287	4.25126	293	0.932391945	-0.23988721	normal	0.966585181	0.003908242	normal	0.961653837	-0.116735006	normal	0.726530763	-0.120389293	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K15341|0|hsa:64858|DCLRE1B, APOLLO, SNM1B, SNMIB; DNA cross-link repair 1B; K15341 DNA cross-link repair 1B protein [EC:3.1.-.-] (A)"	--	[L]	"Replication, recombination and repair"	DNA repair metallo-beta-lactamase;; Beta-lactamase superfamily domain	5' exonuclease Apollo GN=DCLRE1B OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: 5' exonuclease Apollo isoform X1 [Galeopterus variegatus]
ENSG00000118680(MYL12B)	--	167.694721	3208	170.4324972	3431	166.103345	3342	185.0852899	3564	185.5009442	3440	167.4706035	3212	0.987997156	0.120935965	normal	0.990861284	-0.017639354	normal	0.990021958	-0.065501046	normal	0.971576238	0.01207935	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	K12757|5.86169e-114|tup:102471526|myosin regulatory light chain 12B-like; K12757 myosin regulatory light chain 12 (A)	Focal adhesion (ko04510);; Tight junction (ko04530);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810)	[Z]	Cytoskeleton	EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand	Myosin regulatory light chain 12B GN=MYL12B OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: myosin regulatory light chain 12B isoform 1 [Ceratotherium simum simum] 
ENSG00000118689(FOXO3)	--	6.248352126	800	6.930672954	909	5.589079497	719	6.681685589	853	5.94126466	779	6.38826349	806	0.975771228	0.061598903	normal	0.938245808	-0.243645148	normal	0.964362534	0.156186202	normal	0.967880881	-0.015790371	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09408|0|hsa:2309|FOXO3, AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A; forkhead box O3; K09408 forkhead box protein O3 (A)"	Chemokine signaling pathway (ko04062);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Neurotrophin signaling pathway (ko04722);; Prolactin signaling pathway (ko04917);; Endometrial cancer (ko05213);; Non-small cell lung cancer (ko05223)	[K]	Transcription	Fork head domain	Forkhead box protein O3 GN=FOXO3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein O3 [Elephantulus edwardii]
ENSG00000118690(ARMC2)	--	1.4296643	39	1.778159037	61	1.680135857	54	0.852121101	31	0.977915935	34	1.176380825	42	0.974418512	-0.346682689	normal	0.6600791	-0.836532676	normal	0.962695586	-0.359418692	normal	0.35591301	-0.545547435	normal	--	--	--	--	--	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat	Armadillo repeat-containing protein 2 GN=ARMC2 OS=Homo sapiens (Human) PE=2 SV=4	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: armadillo repeat-containing protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000118705(RPN2)	--	135.3547834	6373	141.9160944	6745	133.521514	6267	113.3882281	5416	114.0734763	5304	122.385723	5810	0.975207153	-0.265507654	normal	0.915172085	-0.368070913	normal	0.992436744	-0.117498816	normal	0.165483044	-0.250940965	normal	--	--	Biological Process: protein N-linked glycosylation (GO:0006487);; Cellular Component: oligosaccharyltransferase complex (GO:0008250);; Cellular Component: integral component of membrane (GO:0016021);; 	K12667|0|ggo:101144582|RPN2; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform 1; K12667 oligosaccharyltransferase complex subunit delta (ribophorin II) (A)	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Oligosaccharyltransferase subunit Ribophorin II	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Precursor) GN=RPN2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 isoform X1 [Ailuropoda melanoleuca]
ENSG00000118762(PKD2)	--	18.0611619	1445	16.882381	1386	17.912862	1550	16.506363	1460	15.61763683	1359	20.93079612	1662	0.983629592	-0.015916551	normal	0.981903641	-0.049753534	normal	0.982077086	0.092273768	normal	0.974305101	0.011895134	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04986|0|hsa:5311|PKD2, APKD2, PC2, PKD4, Pc-2, TRPP2; polycystic kidney disease 2 (autosomal dominant); K04986 polycystin 2 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Polycystin cation channel;; Ion transport protein	Polycystin-2 GN=PKD2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: polycystin-2 [Odobenus rosmarus divergens]
ENSG00000118777(ABCG2)	--	9.797918183	721	11.40815039	799	18.675262	692	5.872732833	435	5.76432	420	6.035567444	402	0.003157976	-0.757713434	normal	2.35E-05	-0.946716739	normal	0.001658723	-0.789575701	normal	4.30E-07	-0.836977429	normal	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Cellular Component: membrane (GO:0016020);; Molecular Function: ATPase activity (GO:0016887);; 	"K05681|0|ptr:471251|ABCG2; ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group); K05681 ATP-binding cassette, subfamily G (WHITE), member 2 (A)"	ABC transporters (ko02010);; Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC-2 type transporter;; ABC transporter;; AAA domain	ATP-binding cassette sub-family G member 2 GN=ABCG2 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family G member 2 isoform X1 [Tupaia chinensis] 
ENSG00000118785(SPP1)	--	85.35354409	2491	106.9909023	3077	87.66627302	2520	144.9357823	4232	135.14839	3905	221.85495	6468	0.001992999	0.733431535	normal	0.93305553	0.322230677	normal	1.91E-14	1.351079714	up	0.047884603	0.832457155	normal	--	--	Biological Process: ossification (GO:0001503);; Biological Process: cell adhesion (GO:0007155);; 	K06250|1.07256e-172|ptr:461366|SPP1; secreted phosphoprotein 1; K06250 secreted phosphoprotein 1 (A)	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toll-like receptor signaling pathway (ko04620)	--	--	Osteopontin	Osteopontin (Precursor) GN=SPP1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: osteopontin [Galeopterus variegatus]
ENSG00000118804(STBD1)	--	6.1989665	345	5.871589694	376	5.4887611	345	4.9308803	293	4.7594718	285	6.1927578	357	0.919622307	-0.2652444	normal	0.727887963	-0.419253683	normal	0.968078156	0.040860193	normal	0.460792926	-0.20988665	normal	--	--	Molecular Function: starch binding (GO:2001070);; 	--	--	--	--	Starch binding domain	Starch-binding domain-containing protein 1 GN=STBD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: starch-binding domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000118816(CCNI)	--	103.6168723	2759	102.1013667	2802	96.96555696	2916	95.36301241	2655	100.8452563	2700	123.039705	3138	0.987762901	-0.086216909	normal	0.988043451	-0.074882931	normal	0.988230916	0.09751443	normal	0.95478421	-0.017894801	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-I GN=CCNI OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-I [Eptesicus fuscus]
ENSG00000118849(RARRES1)	--	2.52668	72	1.52274	44	0.95857	27	1.705904	45	3.826499	94	2.961065	81	0.770057996	-0.690099285	normal	0.063239432	1.048529279	normal	0.001078452	1.525029595	up	0.439378065	0.600972964	normal	--	--	--	--	--	--	--	Latexin	Retinoic acid receptor responder protein 1 GN=RARRES1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: retinoic acid receptor responder protein 1 isoform X1 [Mustela putorius furo] 
ENSG00000118855(MFSD1)	--	30.736759	873	27.87348101	858	25.58099408	765	38.615818	1164	37.16518409	991	41.538133	1213	0.764669288	0.383618832	normal	0.960445733	0.186175313	normal	0.019438647	0.655718161	normal	0.011075616	0.410923068	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Major facilitator superfamily domain-containing protein 1 GN=MFSD1 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: major facilitator superfamily domain-containing protein 1 [Ovis aries]
ENSG00000118873(RAB3GAP2)	--	10.43995232	1333	12.15619784	1549	11.65012146	1460	12.46533142	1598	11.27886007	1435	12.55403487	1602	0.956090253	0.230515446	normal	0.977450746	-0.131579456	normal	0.978797528	0.125490208	normal	0.763770602	0.072971972	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab3 GTPase-activating protein regulatory subunit C-terminus;; Rab3 GTPase-activating protein regulatory subunit N-terminus	Rab3 GTPase-activating protein non-catalytic subunit GN=RAB3GAP2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab3 GTPase-activating protein non-catalytic subunit [Canis lupus familiaris]
ENSG00000118894(EEF2KMT)	--	14.32921013	641	11.64504003	565	15.336502	670	12.22581466	565	11.15505681	528	11.31962098	538	0.945785888	-0.212363103	normal	0.96519712	-0.118810448	normal	0.866179034	-0.324028465	normal	0.313525305	-0.223043615	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[R]	General function prediction only	Family of unknown function;; Putative methyltransferase	Putative protein N-methyltransferase FAM86A {ECO:0000305} GN=FAM86A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM86A isoform X1 [Galeopterus variegatus]
ENSG00000118898(PPL)	--	5.789814638	968	3.650323859	626	5.271834848	911	1.526349525	254	1.564219579	260	1.430138645	239	0	-1.954481067	down	1.88E-09	-1.284103754	down	0	-1.931991884	down	5.25E-08	-1.75509891	down	--	--	--	K10386|0|hsa:5493|PPL; periplakin; K10386 periplakin (A)	--	[Z]	Cytoskeleton	Plectin repeat	Periplakin GN=PPL OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: periplakin [Eptesicus fuscus]
ENSG00000118900(UBN1)	--	14.272358	1688	13.6475424	1732	12.7109	1637	14.4067403	1760	15.785154	1859	16.783299	1984	0.985211219	0.029402053	normal	0.983606464	0.080593352	normal	0.944238792	0.268840339	normal	0.545373684	0.127013125	normal	--	--	--	"K17492|0|hsa:29855|UBN1, VT, VT4; ubinuclein 1; K17492 ubinuclein (A)"	--	[KT]	Transcription;; Signal transduction mechanisms	Ubinuclein conserved middle domain;; HPC2 and ubinuclein domain	Ubinuclein-1 GN=UBN1 OS=Homo sapiens (Human) PE=1 SV=2	KT	Transcription;; Signal transduction mechanisms	PREDICTED: ubinuclein-1 isoform X1 [Galeopterus variegatus]
ENSG00000118922(KLF12)	--	2.1195435	387	2.509037837	444	2.1623742	377	1.956121321	358	2.00709934	366	2.15254927	394	0.958872522	-0.142617325	normal	0.89397579	-0.299018844	normal	0.968141401	0.055123354	normal	0.659045708	-0.132803857	normal	[R]	General function prediction only	--	K09205|0|nle:100598179|KLF12; Kruppel-like factor 12; K09205 krueppel-like factor 8/12 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 12 GN=KLF12 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: Krueppel-like factor 12 [Elephantulus edwardii]
ENSG00000118939(UCHL3)	--	15.843525	205	15.33240415	195	19.7882465	259	26.94536219	351	22.73822689	291	20.77854	268	0.024549957	0.740725536	normal	0.413597508	0.552588973	normal	0.966665163	0.040755514	normal	0.079751089	0.444027132	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Cellular Component: intracellular (GO:0005622);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; 	K05609|1.04451e-171|umr:103659168|UCHL3; ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase); K05609 ubiquitin carboxyl-terminal hydrolase L3 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ubiquitin carboxyl-terminal hydrolase, family 1"	Ubiquitin carboxyl-terminal hydrolase isozyme L3 GN=UCHL3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase isozyme L3 isoform X2 [Leptonychotes weddellii]
ENSG00000118946(PCDH17)	--	0	0	0	0	0	0	0.11054378	8	0.229374238	13	0.03932248	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16499|0|hsa:27253|PCDH17, PCDH68, PCH68; protocadherin 17; K16499 protocadherin delta 2 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin-17 (Precursor) GN=PCDH17 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protocadherin-17-like [Odobenus rosmarus divergens]
ENSG00000118960(HS1BP3)	--	24.38267472	1062	36.97663626	1673	28.3882408	1333	17.84641353	811	15.61444052	702	24.69015264	1173	0.656531125	-0.419145871	normal	2.31E-11	-1.272487286	down	0.964650172	-0.192532189	normal	0.128352241	-0.61911124	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	--	--	--	--	PX domain	HCLS1-binding protein 3 GN=HS1BP3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: HCLS1-binding protein 3 [Trichechus manatus latirostris]
ENSG00000118961(LDAH)	--	20.54253334	846	17.509245	850	21.31863903	857	19.10760186	742	15.63998854	675	21.76954445	770	0.947373953	-0.219644402	normal	0.828232785	-0.353294792	normal	0.964122081	-0.162425662	normal	0.210069027	-0.244344888	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2305);; Alpha/beta hydrolase family;; Alpha/beta hydrolase family	UPF0554 protein C2orf43 GN=C2orf43 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0554 protein C2orf43 homolog isoform X1 [Galeopterus variegatus]
ENSG00000118965(WDR35)	--	10.76990732	1093	8.999674057	926	9.032083195	941	6.124438416	678	6.736193022	760	6.63198966	728	0.004559921	-0.7184729	normal	0.893564549	-0.305886893	normal	0.774913237	-0.377855344	normal	0.00354782	-0.471586348	normal	--	--	--	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 35 GN=WDR35 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: WD repeat-containing protein 35 isoform X1 [Mustela putorius furo] 
ENSG00000118971(CCND2)	--	0.00934243	1	0.00920166	1	0	0	0.0185989	2	0.058566	3	0.0278511	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: nucleus (GO:0005634);; 	K10151|0|ptr:747123|CCND2; cyclin D2; K10151 cyclin D2 (A)	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917);; Measles (ko05162);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G1/S-specific cyclin-D2 GN=CCND2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: G1/S-specific cyclin-D2 [Galeopterus variegatus]
ENSG00000118972(FGF23)	--	0	0	0.0189677	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04358|0|hsa:8074|FGF23, ADHR, FGFN, HPDR2, HYPF, PHPTC; fibroblast growth factor 23; K04358 fibroblast growth factor (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 23 C-terminal peptide (Precursor) GN=FGF23 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 23 [Trichechus manatus latirostris]
ENSG00000118985(ELL2)	--	9.791844	955	11.63338099	1017	12.38579322	1100	14.959886	1357	12.744075	1176	13.452172	1233	0.435987485	0.475371344	normal	0.963074813	0.187881837	normal	0.970859807	0.156174936	normal	0.119366107	0.272507711	normal	--	--	Biological Process: transcription elongation from RNA polymerase II promoter (GO:0006368);; Cellular Component: transcription elongation factor complex (GO:0008023);; 	"K15183|0|hsa:22936|ELL2; elongation factor, RNA polymerase II, 2; K15183 RNA polymerase II elongation factor ELL (A)"	--	[K]	Transcription	RNA polymerase II elongation factor ELL;; Occludin homology domain	RNA polymerase II elongation factor ELL2 GN=ELL2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: RNA polymerase II elongation factor ELL2 [Ceratotherium simum simum]
ENSG00000118997(DNAH7)	--	0.594226767	69	0.735853372	77	0.307201995	49	0.428643538	44	0.431897382	71	0.435209188	34	0.816124652	-0.661323187	normal	0.969532074	-0.135689748	normal	0.944578262	-0.516306855	normal	0.48846016	-0.410327382	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Biological Process: microtubule-based movement (GO:0007018);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:56171|DNAH7; dynein, axonemal, heavy chain 7; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D4;; ATP-binding dynein motor region D5;; P-loop containing dynein motor region D3;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA)"	"Dynein heavy chain 7, axonemal GN=DNAH7 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 7, axonemal [Ceratotherium simum simum]"
ENSG00000119004(CYP20A1)	--	5.444225107	417	6.624032055	541	4.128835001	412	3.273909202	273	3.65726473	264	3.80274546	356	0.088789155	-0.639044908	normal	4.98E-06	-1.052212855	down	0.940202637	-0.218196116	normal	0.010666911	-0.638180552	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07435|0|hsa:57404|CYP20A1, CYP-M; cytochrome P450, family 20, subfamily A, polypeptide 1; K07435 cytochrome P450, family 20, subfamily A (A)"	--	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 20A1 GN=CYP20A1 OS=Homo sapiens (Human) PE=2 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 20A1-like isoform 1 [Ceratotherium simum simum]
ENSG00000119013(NDUFB3)	--	55.86971	508	58.504929	561	51.15146	494	46.3243	452	37.5454	334	41.15185	404	0.947845413	-0.198700396	normal	0.005187809	-0.766868471	normal	0.894462169	-0.297438531	normal	0.041552473	-0.415189001	normal	--	--	--	"K03959|6.83414e-40|ptr:459871|NDUFB3; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa; K03959 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 3 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	NADH-ubiquinone oxidoreductase B12 subunit family	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 GN=NDUFB3 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 [Ceratotherium simum simum]
ENSG00000119041(GTF3C3)	--	18.59927052	1212	16.14280703	1062	18.06274355	1150	11.2239223	745	10.24067847	677	9.941777985	659	0.002945255	-0.731713831	normal	0.018270258	-0.669777299	normal	0.000395648	-0.810149005	normal	6.50E-07	-0.739939149	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15201|0|ptr:459846|GTF3C3; general transcription factor IIIC, polypeptide 3, 102kDa; K15201 general transcription factor 3C polypeptide 3 (transcription factor C subunit 4) (A)"	--	[K]	Transcription	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	General transcription factor 3C polypeptide 3 GN=GTF3C3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor 3C polypeptide 3 [Camelus ferus] 
ENSG00000119042(SATB2)	--	3.903140702	372	3.34629189	293	3.33302998	318	2.17956685	192	2.663399092	235	2.239735319	191	0.000134932	-0.979290092	normal	0.871425131	-0.337715733	normal	0.031370779	-0.739160132	normal	0.002299783	-0.690707477	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	CUT domain;; Homeobox domain	DNA-binding protein SATB2 GN=SATB2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-binding protein SATB2 [Loxodonta africana] 
ENSG00000119048(UBE2B)	--	20.393016	580	27.919524	781	24.98764726	654	24.80619729	784	20.55967886	636	27.855568	754	0.709579022	0.403047198	normal	0.877980362	-0.317040697	normal	0.953467272	0.196558816	normal	0.770700335	0.088036268	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; Prokaryotic E2 family B	Ubiquitin-conjugating enzyme E2 B GN=UBE2B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 B isoform X1 [Capra hircus]
ENSG00000119121(TRPM6)	--	1.38616622	135	1.187682772	111	1.0003039	93	2.899577381	277	2.761955781	264	2.124021401	209	0.000456197	0.998006083	normal	7.28E-06	1.217474504	up	0.000130716	1.147135302	up	1.02E-05	1.123200765	up	--	--	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein tetramerization (GO:0051262);; Biological Process: transmembrane transport (GO:0055085);; 	"K04981|0|ptr:472957|TRPM6; transient receptor potential cation channel, subfamily M, member 6; K04981 transient receptor potential cation channel subfamily M member 6 [EC:2.7.11.1] (A)"	Mineral absorption (ko04978)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Alpha-kinase family;; Ion transport protein	Transient receptor potential cation channel subfamily M member 6 GN=TRPM6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily M member 6 [Panthera tigris altaica]
ENSG00000119125(GDA)	--	0.14619856	12	0.249901854	9	0.07907255	3	2.533182358	201	3.109213897	225	1.727688207	121	0	3.874292764	up	0	4.409627389	up	0	4.756073144	up	7.57E-13	4.486485376	up	[FR]	Nucleotide transport and metabolism;; General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	"K01487|0|hsa:9615|GDA, CYPIN, GUANASE, NEDASIN; guanine deaminase (EC:3.5.4.3); K01487 guanine deaminase [EC:3.5.4.3] (A)"	Purine metabolism (ko00230)	[FQ]	"Nucleotide transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Amidohydrolase family;; Amidohydrolase	Guanine deaminase GN=GDA OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: guanine deaminase isoform X1 [Tupaia chinensis]
ENSG00000119138(KLF9)	--	3.13496	267	3.66644	314	3.24097	276	2.29835	197	2.96586	253	3.16302	271	0.674775657	-0.466338731	normal	0.874188542	-0.331272432	normal	0.966985735	-0.034476213	normal	0.3542704	-0.26962605	normal	[R]	General function prediction only	--	K09208|3.12584e-170|ptr:464520|KLF9; Kruppel-like factor 9; K09208 krueppel-like factor 9/13/14/16 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Krueppel-like factor 9 GN=KLF9 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	Krueppel-like factor 9 [Sus scrofa] 
ENSG00000119139(TJP2)	--	0.770375867	76	2.401760355	96	0.866388638	58	4.640537699	356	4.084649613	351	3.73309098	406	0	2.174682797	up	2.63E-14	1.832803145	up	0	2.767413355	up	4.19E-23	2.253226584	up	--	--	Molecular Function: protein binding (GO:0005515);; 	K06098|0|pon:100434798|TJP2; tight junction protein 2; K06098 tight junction protein 2 (A)	Tight junction (ko04530)	[T]	Signal transduction mechanisms	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Guanylate kinase;; Variant SH3 domain	Tight junction protein ZO-2 GN=TJP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tight junction protein ZO-2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000119185(ITGB1BP1)	--	39.400976	1689	39.94835648	1757	42.80301405	1849	45.55711881	1899	33.82113727	1428	44.75139302	1660	0.979511118	0.138119779	normal	0.900486725	-0.320238406	normal	0.975955046	-0.163712034	normal	0.623727906	-0.10806802	normal	--	--	--	--	--	--	--	Beta-1 integrin binding protein	Integrin beta-1-binding protein 1 GN=ITGB1BP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: integrin beta-1-binding protein 1 [Equus caballus] 
ENSG00000119203(CPSF3)	--	41.68699823	1829	41.50161953	1821	40.28852902	1745	33.8021076	1494	33.3021423	1439	27.629544	1212	0.896740365	-0.32240691	normal	0.844695534	-0.360752996	normal	0.206406444	-0.533570762	normal	0.008546795	-0.402106883	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K14403|0|hsa:51692|CPSF3, CPSF-73, CPSF73; cleavage and polyadenylation specific factor 3, 73kDa; K14403 cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-] (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term;; Beta-Casp domain;; Metallo-beta-lactamase superfamily;; RNA-metabolising metallo-beta-lactamase;; Beta-lactamase superfamily domain;; Beta-lactamase superfamily domain	Cleavage and polyadenylation specificity factor subunit 3 GN=CPSF3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: cleavage and polyadenylation specificity factor subunit 3 [Odobenus rosmarus divergens]
ENSG00000119227(PIGZ)	--	3.770746001	157	2.550154658	111	2.15916321	99	2.435919568	110	1.450084192	70	1.86545227	74	0.681823314	-0.537769715	normal	0.560305432	-0.67487551	normal	0.909056826	-0.420734589	normal	0.210376342	-0.553998394	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K08098|0|hsa:80235|PIGZ, GPI-MT-IV, PIG-Z, SMP3; phosphatidylinositol glycan anchor biosynthesis, class Z; K08098 phosphatidylinositol glycan, class Z [EC:2.4.1.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[G]	Carbohydrate transport and metabolism	Alg9-like mannosyltransferase family	GPI mannosyltransferase 4 GN=PIGZ OS=Homo sapiens (Human) PE=2 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: GPI mannosyltransferase 4 [Galeopterus variegatus]
ENSG00000119231(SENP5)	--	5.885727073	576	5.7685371	626	6.065747003	610	5.101905399	558	6.779130457	639	6.232195	618	0.970402178	-0.076428805	normal	0.973620987	0.008207093	normal	0.973967018	0.01048034	normal	0.962333677	-0.018443743	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	K08594|0|hsa:205564|SENP5; SUMO1/sentrin specific peptidase 5 (EC:3.4.22.68); K08594 sentrin-specific protease 5 [EC:3.4.22.68] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ulp1 protease family, C-terminal catalytic domain"	Sentrin-specific protease 5 GN=SENP5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sentrin-specific protease 5 isoform X1 [Leptonychotes weddellii]
ENSG00000119242(CCDC92)	--	12.95927698	656	12.353667	592	10.786779	570	10.86044	554	14.07258547	684	16.828874	778	0.913754951	-0.273942892	normal	0.95434405	0.186529	normal	0.593830755	0.439514818	normal	0.667064915	0.128853044	normal	--	--	--	K16452|0|hsa:80212|CCDC92; coiled-coil domain containing 92; K16452 coiled-coil domain-containing protein 92 (A)	--	--	--	Coiled-coil domain of unknown function	Coiled-coil domain-containing protein 92 GN=CCDC92 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 92-like isoform X1 [Sus scrofa]
ENSG00000119280(C1orf198)	--	9.768021462	635	10.127656	636	8.863842351	581	11.84902362	761	11.68440444	737	9.974107528	661	0.940943241	0.229799169	normal	0.954273676	0.190789569	normal	0.956894534	0.177387514	normal	0.359657013	0.199529601	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf198 GN=C1orf198 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf198 homolog [Odobenus rosmarus divergens]
ENSG00000119283(TRIM67)	--	0.035739162	6	0.071860996	8	0.017379627	2	0.017900847	3	0.081443772	7	0.029468419	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10649|0|hsa:440730|TRIM67, TNL; tripartite motif containing 67; K10649 tripartite motif-containing protein 9/67 (A)"	--	[S]	Function unknown	"SPRY domain;; B-box zinc finger;; Fibronectin type III domain;; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 67 GN=TRIM67 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: tripartite motif-containing protein 67 isoform X1 [Mustela putorius furo]
ENSG00000119285(HEATR1)	--	23.889542	3376	24.648614	3368	26.13366	3442	23.362364	3389	24.57055	3392	23.027587	3357	0.990972608	-0.02527605	normal	0.990781885	-0.011177525	normal	0.990742931	-0.044346272	normal	0.921405102	-0.027987867	normal	--	--	--	"K14550|0|hsa:55127|HEATR1, BAP28, UTP10; HEAT repeat containing 1; K14550 U3 small nucleolar RNA-associated protein 10 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[S]	Function unknown	BP28CT (NUC211) domain;; U3 small nucleolar RNA-associated protein 10;; HEAT repeat;; HEAT repeats	"HEAT repeat-containing protein 1, N-terminally processed GN=HEATR1 OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	PREDICTED: HEAT repeat-containing protein 1 [Ceratotherium simum simum]
ENSG00000119314(PTBP3)	--	60.39030299	5221	62.21563397	5431	59.9844598	4876	87.47985645	7629	89.38214222	7533	89.77702215	7857	0.410406635	0.516209203	normal	0.743760152	0.450473171	normal	0.0118026	0.679821352	normal	0.000315571	0.546681645	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K17844|0|pon:100431908|PTBP3, ROD1; polypyrimidine tract-binding protein 3; K17844 polypyrimidine tract-binding protein 3 (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Polypyrimidine tract-binding protein 3 GN=PTBP3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: polypyrimidine tract-binding protein 3 [Oryctolagus cuniculus]
ENSG00000119318(RAD23B)	--	80.982412	5678	84.5726239	5962	85.515374	5985	86.511567	6027	79.6100553	5550	80.20249515	5634	0.993833906	0.055210451	normal	0.99167432	-0.124702368	normal	0.992928292	-0.095458261	normal	0.835102099	-0.055670451	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: damaged DNA binding (GO:0003684);; Molecular Function: protein binding (GO:0005515);; Biological Process: nucleotide-excision repair (GO:0006289);; Biological Process: proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161);; 	K10839|1.26923e-163|cge:100763817|Rad23b; RAD23 homolog B (S. cerevisiae); K10839 UV excision repair protein RAD23 (A)	Nucleotide excision repair (ko03420);; Protein processing in endoplasmic reticulum (ko04141)	[L]	"Replication, recombination and repair"	XPC-binding domain;; Ubiquitin family;; UBA/TS-N domain;; Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin-2 like Rad60 SUMO-like	UV excision repair protein RAD23 homolog B GN=RAD23B OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: UV excision repair protein RAD23 homolog B [Sorex araneus]
ENSG00000119321(FKBP15)	--	8.598223	1003	8.788836	1056	8.160357894	1019	10.491131	1281	9.73936	1218	9.689362	1160	0.882278021	0.321679688	normal	0.964586189	0.184231915	normal	0.965469879	0.178430962	normal	0.214267858	0.227938275	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K17478|0|hsa:23307|FKBP15, FKBP133, KIAA0674, PPP1R76; FK506 binding protein 15, 133kDa (EC:5.2.1.8); K17478 FK506-binding protein 15 (A)"	--	[S]	Function unknown	FKBP-type peptidyl-prolyl cis-trans isomerase	FK506-binding protein 15 GN=FKBP15 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: FK506-binding protein 15 [Galeopterus variegatus]
ENSG00000119326(CTNNAL1)	--	27.07568552	1279	18.01234353	848	28.93018155	1348	30.03163284	1396	21.88843612	1032	14.23321637	672	0.979621941	0.095340771	normal	0.931027762	0.26145701	normal	5.55E-07	-1.010939428	down	0.782702731	-0.187554988	normal	--	--	Biological Process: cell adhesion (GO:0007155);; Molecular Function: actin filament binding (GO:0051015);; 	--	--	[W]	Extracellular structures	Vinculin family	Alpha-catulin GN=CTNNAL1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: alpha-catulin [Odobenus rosmarus divergens]
ENSG00000119328(FAM206A)	--	9.784841304	343	10.07171157	353	10.1211001	351	10.75230341	380	11.02880501	388	11.71040148	414	0.962410237	0.116462822	normal	0.961975193	0.114493943	normal	0.936087952	0.228959026	normal	0.602806052	0.154045678	normal	--	--	--	--	--	[E]	Amino acid transport and metabolism	Glycine cleavage H-protein	Protein Simiate GN=FAM206A OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: protein FAM206A [Canis lupus familiaris]
ENSG00000119333(WDR34)	--	73.093023	2187	73.967815	2276	81.679051	2501	69.020298	2102	63.105367	1899	70.020159	2103	0.985453796	-0.087959775	normal	0.941706362	-0.282481404	normal	0.956251775	-0.258177177	normal	0.236866777	-0.211194351	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	"WD domain, G-beta repeat"	WD repeat-containing protein 34 GN=WDR34 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: WD repeat-containing protein 34 isoform X1 [Ailuropoda melanoleuca]
ENSG00000119335(SET)	--	244.7924426	10233	265.42219	11145	245.62128	10530	269.7269192	11756	243.7799779	10461	234.2693022	10225	0.993671042	0.169312109	normal	0.995254311	-0.112786604	normal	0.996152145	-0.050688647	normal	0.996330974	0.00225823	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11290|3.02926e-157|pps:100978402|SET; SET nuclear proto-oncogene; K11290 template-activating factor I (A)	--	[L]	"Replication, recombination and repair"	Nucleosome assembly protein (NAP)	Protein SET GN=SET OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: protein SET isoform 1 [Tursiops truncatus]
ENSG00000119383(PTPA)	--	85.30260813	3316	83.92084967	3252	79.23077614	3254	91.39333407	3508	91.76614524	3358	103.3591442	3629	0.990674596	0.050349795	normal	0.99053179	0.024837049	normal	0.98615439	0.149000762	normal	0.756761838	0.07449231	normal	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	Molecular Function: phosphatase activator activity (GO:0019211);; 	K17605|0|mcc:716874|serine/threonine-protein phosphatase 2A activator-like; K17605 serine/threonine-protein phosphatase 2A activator (A)	--	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	Phosphotyrosyl phosphate activator (PTPA) protein	Serine/threonine-protein phosphatase 2A activator GN=PPP2R4 OS=Homo sapiens (Human) PE=1 SV=3	DT	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	PREDICTED: serine/threonine-protein phosphatase 2A activator isoform 1 [Ceratotherium simum simum]
ENSG00000119392(GLE1)	--	17.36820677	1195	17.35470678	1199	18.632469	1276	15.841807	1082	14.63550911	998	16.139929	1105	0.967085274	-0.173907265	normal	0.918754893	-0.285750815	normal	0.95699186	-0.215598564	normal	0.219867893	-0.225534947	normal	--	--	Cellular Component: nuclear pore (GO:0005643);; Biological Process: poly(A)+ mRNA export from nucleus (GO:0016973);; 	"K18723|0|hsa:2733|GLE1, GLE1L, LCCS, LCCS1, hGLE1; GLE1 RNA export mediator; K18723 nucleoporin GLE1 (A)"	--	[A]	RNA processing and modification	GLE1-like protein	Nucleoporin GLE1 GN=GLE1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: nucleoporin GLE1 isoform X1 [Galeopterus variegatus]
ENSG00000119396(RAB14)	--	34.53347	1947	37.885532	2135	37.96005311	2072	39.351844	2243	39.024872	2174	38.4956057	2176	0.977107324	0.173217047	normal	0.987210365	0.004686023	normal	0.986429676	0.062318724	normal	0.739197536	0.078132681	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07881|5.92503e-161|umr:103670369|RAB14; RAB14, member RAS oncogene family; K07881 Ras-related protein Rab-14 (A)"	AMPK signaling pathway (ko04152)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-14 GN=RAB14 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	"Ras-related protein Rab-14, partial [Bos mutus] "
ENSG00000119397(CNTRL)	--	3.192207956	557	3.98801335	595	4.026834202	611	3.013588005	489	2.678980119	428	2.589122138	446	0.941985183	-0.218032653	normal	0.427040463	-0.495214127	normal	0.535998216	-0.461078686	normal	0.045751031	-0.392670962	normal	--	--	--	"K16770|0|hsa:11064|CNTRL, CEP1, CEP110, FAN, bA165P4.1; centriolin; K16770 centriolin (A)"	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine-rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat	Centriolin GN=CNTRL OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centriolin isoform X2 [Tupaia chinensis]
ENSG00000119401(TRIM32)	--	17.718111	939	20.77390119	943	15.16595777	916	15.6032538	864	18.76714724	973	16.38120433	893	0.967719202	-0.15066899	normal	0.978365853	0.023718031	normal	0.977676482	-0.044903779	normal	0.836988865	-0.056579399	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K10607|0|hsa:22954|TRIM32, BBS11, HT2A, LGMD2H, TATIP; tripartite motif containing 32; K10607 tripartite motif-containing protein 32 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	"NHL repeat;; RING-type zinc-finger;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	E3 ubiquitin-protein ligase TRIM32 GN=TRIM32 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM32 [Galeopterus variegatus]
ENSG00000119402(FBXW2)	--	21.5662841	1660	20.702185	1661	22.149431	1572	22.861435	1821	23.3845	1921	23.788859	1816	0.982280622	0.102624711	normal	0.971799923	0.18821943	normal	0.968482058	0.199692665	normal	0.402534623	0.16258404	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10261|0|umr:103670375|FBXW2; F-box and WD repeat domain containing 2; K10261 F-box and WD-40 domain protein 2 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat;; F-box-like;; F-box domain"	F-box/WD repeat-containing protein 2 GN=FBXW2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	F-box/WD repeat-containing protein 2 [Pteropus alecto]
ENSG00000119403(PHF19)	--	48.46697523	1187	51.22563186	1266	49.23331155	1238	45.97860874	1161	37.54753682	980	44.63924276	1107	0.979986683	-0.062702158	normal	0.76082413	-0.390318768	normal	0.968573952	-0.169428539	normal	0.274663114	-0.205864634	normal	--	--	--	K11486|0|mcf:102128213|PHF19; PHD finger protein 19; K11486 polycomb-like protein 3 (A)	--	[R]	General function prediction only	Polycomb-like MTF2 factor 2;; PHD-finger	PHD finger protein 19 GN=PHF19 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: PHD finger protein 19 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000119408(NEK6)	--	24.63675055	2731	20.70056449	2166	22.26011728	2628	35.20448312	3646	27.63200392	2918	25.53684306	2874	0.834864115	0.385864549	normal	0.769855057	0.408273677	normal	0.986027744	0.120736887	normal	0.142429604	0.304976248	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08857|0|hsa:10783|NEK6, SID6-1512; NIMA-related kinase 6 (EC:2.7.11.1); K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase Nek6 GN=NEK6 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase Nek6 isoform X1 [Tupaia chinensis]
ENSG00000119411(BSPRY)	--	0.0240192	1	0.0466524	2	0.138572	5	0	0	0.0234144	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPRY-associated domain;; SPRY domain;; B-box zinc finger	B box and SPRY domain-containing protein GN=BSPRY OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: B box and SPRY domain-containing protein [Odobenus rosmarus divergens]
ENSG00000119414(PPP6C)	--	19.12090774	922	18.026694	919	18.67207723	932	18.283772	953	17.29773491	889	14.990649	774	0.978689124	0.016849583	normal	0.975994244	-0.069192226	normal	0.918732388	-0.275796014	normal	0.660686585	-0.105859498	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K15498|0|hsa:5537|PPP6C, PP6, PP6C; protein phosphatase 6, catalytic subunit (EC:3.1.3.16); K15498 serine/threonine-protein phosphatase 6 catalytic subunit [EC:3.1.3.16] (A)"	--	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	Calcineurin-like phosphoesterase	"Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed GN=PPP6C OS=Homo sapiens (Human) PE=1 SV=1"	DT	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	PREDICTED: serine/threonine-protein phosphatase 6 catalytic subunit isoform X1 [Eptesicus fuscus]
ENSG00000119421(NDUFA8)	--	58.53043	721	64.08426	827	65.54911	835	65.64083	842	57.78551	696	63.6961	793	0.956072517	0.192608629	normal	0.921169812	-0.269688237	normal	0.974378059	-0.082593257	normal	0.856106482	-0.053175631	normal	--	--	--	"K03952|1.23105e-125|ptr:464897|NDUFA8; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa; K03952 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 8 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	CHCH domain	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 GN=NDUFA8 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 [Elephantulus edwardii]
ENSG00000119431(HDHD3)	--	16.20104	443	19.27827	543	14.01103	380	17.55533	480	20.22253	543	17.04379	462	0.967620876	0.084613487	normal	0.971734051	-0.02136705	normal	0.913456356	0.272616578	normal	0.758315786	0.098792021	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like	Haloacid dehalogenase-like hydrolase domain-containing protein 3 GN=HDHD3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: haloacid dehalogenase-like hydrolase domain-containing protein 3 [Galeopterus variegatus]
ENSG00000119446(RBM18)	--	7.825776	585	8.45308	625	7.485	546	7.88521	595	7.84824	588	8.874999	666	0.973454152	-0.00636265	normal	0.967600181	-0.109194136	normal	0.911501549	0.277632452	normal	0.867459423	0.053390728	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Probable RNA-binding protein 18 GN=RBM18 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: probable RNA-binding protein 18 isoform X2 [Oryctolagus cuniculus] 
ENSG00000119457(SLC46A2)	--	0.0251164	1	0.123161	5	0	0	0.0500196	2	0.0244328	0	0.149029	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14614|0|hsa:57864|SLC46A2, Ly110, TSCOT; solute carrier family 46, member 2; K14614 MFS transporter, PCFT/HCP family, solute carrier family 46 (thymic stromal cotransporter), member 2 (A)"	--	[R]	General function prediction only	Major Facilitator Superfamily	Thymic stromal cotransporter homolog GN=SLC46A2 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: thymic stromal cotransporter homolog [Galeopterus variegatus]
ENSG00000119471(HSDL2)	--	33.19934	1905	31.63863	1820	35.30182	1982	45.04242	2654	38.84317	2230	38.82162	2244	0.602288402	0.447238292	normal	0.946908783	0.27147462	normal	0.977654675	0.170701792	normal	0.065496285	0.299128761	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[R]	General function prediction only	SCP-2 sterol transfer family;; short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Hydroxysteroid dehydrogenase-like protein 2 GN=HSDL2 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: hydroxysteroid dehydrogenase-like protein 2 [Ovis aries]
ENSG00000119487(MAPKAP1)	--	41.10969736	2202	47.62674692	2387	42.74524476	2102	50.104571	2492	43.5132205	2439	45.31062363	2271	0.981955896	0.147560513	normal	0.988185406	0.00965858	normal	0.984803191	0.103202147	normal	0.713737845	0.084549937	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Stress-activated map kinase interacting protein 1 (SIN1)	Target of rapamycin complex 2 subunit MAPKAP1 GN=MAPKAP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: target of rapamycin complex 2 subunit MAPKAP1 isoform X1 [Felis catus] 
ENSG00000119508(NR4A3)	--	0.288683712	25	0.895840363	76	0.298684211	20	0.203723205	14	0.188308114	16	0.661472811	52	0.956291671	-0.800733041	normal	1.92E-06	-2.166350001	down	0.135653205	1.306826397	normal	0.759741595	-0.580180572	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08559|0|mcc:717560|NR4A3; nuclear receptor subfamily 4, group A, member 3; K08559 nuclear receptor subfamily 4 group A member 3 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor subfamily 4 group A member 3 GN=NR4A3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nuclear receptor subfamily 4 group A member 3 isoform X1 [Bos taurus] 
ENSG00000119509(INVS)	--	6.263308	732	6.625516	740	8.01087049	863	6.956132	843	5.851175	747	6.7803623	789	0.961305387	0.172519099	normal	0.975526515	-0.007827664	normal	0.968669957	-0.137374841	normal	0.989389689	0.005786638	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; IQ calmodulin-binding motif	Inversin GN=INVS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: inversin isoform X1 [Tupaia chinensis]
ENSG00000119514(GALNT12)	--	12.18773857	352	6.00739839	191	7.803172556	280	20.2684908	748	19.43693323	679	11.1115825	429	9.41E-07	1.053405942	up	0	1.800352075	up	0.147384908	0.60460191	normal	0.006780623	1.15072296	up	--	--	--	"K00710|0|hsa:79695|GALNT12, CRCS1, GalNAc-T12; polypeptide N-acetylgalactosaminyltransferase 12 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2;; N-terminal domain of galactosyltransferase	Polypeptide N-acetylgalactosaminyltransferase 12 GN=GALNT12 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 12 [Galeopterus variegatus]
ENSG00000119522(DENND1A)	--	13.5141746	1038	13.0020928	1008	14.0037244	1069	13.1594605	870	13.9463109	846	12.20845	883	0.913860936	-0.285089731	normal	0.922862869	-0.273743673	normal	0.916021526	-0.283625763	normal	0.115321741	-0.28234642	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; uDENN domain;; dDENN domain	DENN domain-containing protein 1A GN=DENND1A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 1A [Orcinus orca]
ENSG00000119523(ALG2)	--	21.869455	739	25.19278	831	21.41717	694	25.8711427	878	25.39098648	835	29.33084414	976	0.948525608	0.217399261	normal	0.976827777	-0.014472563	normal	0.412195447	0.48276282	normal	0.248353437	0.227052827	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K03843|0|hsa:85365|ALG2, CDGIi, NET38, hALPG2; ALG2, alpha-1,3/1,6-mannosyltransferase (EC:2.4.1.132 2.4.1.257); K03843 alpha-1,3/alpha-1,6-mannosyltransferase [EC:2.4.1.132 2.4.1.257] (A)"	N-Glycan biosynthesis (ko00510)	[M]	Cell wall/membrane/envelope biogenesis	Glycosyl transferases group 1;; Glycosyl transferase 4-like domain;; Glycosyl transferases group 1;; Glycosyltransferase Family 4;; Glycosyl transferases group 1	"Alpha-1,3/1,6-mannosyltransferase ALG2 GN=ALG2 OS=Homo sapiens (Human) PE=1 SV=1"	M	Cell wall/membrane/envelope biogenesis	"PREDICTED: alpha-1,3/1,6-mannosyltransferase ALG2 [Lipotes vexillifer]"
ENSG00000119535(CSF3R)	--	0	0	0	0	0	0	0.020450616	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05061|0|hsa:1441|CSF3R, CD114, GCSFR; colony stimulating factor 3 receptor (granulocyte); K05061 granulocyte colony-stimulating factor receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Pathways in cancer (ko05200)	--	--	Ig-like C2-type domain;; Fibronectin type III domain	Granulocyte colony-stimulating factor receptor (Precursor) GN=CSF3R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: granulocyte colony-stimulating factor receptor isoform 1 [Ceratotherium simum simum]
ENSG00000119537(KDSR)	--	13.83682304	999	12.95423096	948	19.73621555	957	23.0430281	1323	19.35838212	1133	19.80690065	1374	0.792916369	0.373923101	normal	0.946551167	0.235418444	normal	0.281354056	0.512819852	normal	0.018957397	0.378136973	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K04708|0|pon:100438442|KDSR; 3-ketodihydrosphingosine reductase; K04708 3-dehydrosphinganine reductase [EC:1.1.1.102] (A)	Sphingolipid metabolism (ko00600)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase	3-ketodihydrosphingosine reductase (Precursor) GN=KDSR OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 3-ketodihydrosphingosine reductase [Camelus bactrianus]
ENSG00000119541(VPS4B)	--	13.89590665	781	15.00870908	847	14.28800136	794	16.28410365	927	16.91421295	949	15.59470584	879	0.950039312	0.216024096	normal	0.968600107	0.142379305	normal	0.968722551	0.138182481	normal	0.443668954	0.16447261	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: DNA helicase activity (GO:0003678);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	K12196|0|pps:100985727|VPS4B; vacuolar protein sorting 4 homolog B (S. cerevisiae); K12196 vacuolar protein-sorting-associated protein 4 (A)	Endocytosis (ko04144)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; Vps4 C terminal oligomerisation domain;; MIT (microtubule interacting and transport) domain;; AAA domain;; AAA domain;; IstB-like ATP binding protein;; TIP49 C-terminus;; AAA domain (dynein-related subfamily);; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (Cdc48 subfamily)	Vacuolar protein sorting-associated protein 4B GN=VPS4B OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: vacuolar protein sorting-associated protein 4B [Galeopterus variegatus]
ENSG00000119547(ONECUT2)	--	1.05716	286	0.995199	266	1.14089	301	1.31692	356	1.21246	328	1.2244	332	0.908653217	0.283661805	normal	0.91208174	0.279410275	normal	0.959755547	0.132494253	normal	0.416879329	0.231030245	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	CUT domain;; Homeobox domain	One cut domain family member 2 GN=ONECUT2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: one cut domain family member 2 [Monodelphis domestica]
ENSG00000119559(C19orf25)	--	11.34000728	806	11.54135575	774	12.64705172	989	12.56804204	769	11.39601202	688	12.7900606	913	0.972549291	-0.098436367	normal	0.955237514	-0.190955548	normal	0.972515688	-0.123450575	normal	0.641390743	-0.13662012	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0449	UPF0449 protein C19orf25 GN=C19orf25 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0449 protein C19orf25 homolog isoform X1 [Myotis lucifugus] 
ENSG00000119574(ZBTB45)	--	16.009025	567	15.24129	528	16.77761	603	18.45352835	660	17.53891	599	19.88878	703	0.953807491	0.187812994	normal	0.958838532	0.160160621	normal	0.947046691	0.212581032	normal	0.414756296	0.18763208	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10516|0|hsa:84878|ZBTB45, ZNF499; zinc finger and BTB domain containing 45; K10516 zinc finger and BTB domain-containing protein 45 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger and BTB domain-containing protein 45 GN=ZBTB45 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 45 [Odobenus rosmarus divergens]
ENSG00000119596(YLPM1)	--	16.097502	2601	16.643783	2714	16.9346788	2745	18.38369088	2943	19.871816	3197	16.25669282	2732	0.983969901	0.147307043	normal	0.975036765	0.214761108	normal	0.989492331	-0.015131751	normal	0.581785096	0.117186902	normal	--	--	--	"K17602|0|hsa:56252|YLPM1, C14orf170, PPP1R169, ZAP113, ZAP3; YLP motif containing 1; K17602 YLP motif-containing protein 1 (A)"	--	[V]	Defense mechanisms	AAA domain	YLP motif-containing protein 1 GN=YLPM1 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	"PREDICTED: YLP motif-containing protein 1, partial [Galeopterus variegatus]"
ENSG00000119599(DCAF4)	--	7.617449935	373	6.097233747	313	6.592648512	340	5.890310841	300	7.549440743	382	5.487030295	276	0.853009295	-0.343464169	normal	0.918549197	0.264823617	normal	0.892435232	-0.307636327	normal	0.719007111	-0.120179756	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K11799|0|ggo:101131652|DCAF4; DDB1- and CUL4-associated factor 4 isoform 1; K11799 WD repeat-containing protein 21A (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 4 GN=DCAF4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 4 isoform X1 [Mustela putorius furo] 
ENSG00000119608(PROX2)	--	0.178968	11	0.16244	10	0.370967	22	0.210882	13	0.331057	20	0.209024	13	--	--	--	0.963139203	0.882720614	normal	0.97233978	-0.703732741	normal	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	Homeo-prospero domain	Prospero homeobox protein 2 GN=PROX2 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: prospero homeobox protein 2 [Ceratotherium simum simum]
ENSG00000119616(FCF1)	--	30.7866934	1038	32.09230798	1085	35.55903795	1153	44.44605671	1480	42.49801506	1397	33.99406461	1178	0.41557431	0.480360272	normal	0.860638073	0.342788377	normal	0.981178684	0.022626224	normal	0.093100786	0.286065114	normal	[R]	General function prediction only	Cellular Component: small-subunit processome (GO:0032040);; 	K14566|5.69569e-128|ptr:467509|FCF1; FCF1 rRNA-processing protein; K14566 U3 small nucleolar RNA-associated protein 24 (A)	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	Fcf1	rRNA-processing protein FCF1 homolog GN=FCF1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: rRNA-processing protein FCF1 homolog [Galeopterus variegatus]
ENSG00000119630(PGF)	--	1.249739774	40	0.658685874	25	1.011416974	33	0.547888361	18	0.986041962	31	0.241625312	8	0.615389221	-1.117258453	normal	0.980833863	0.27400677	normal	0.071242094	-1.866696579	normal	0.226639147	-0.804017741	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	"K16859|3.21039e-76|hsa:5228|PGF, D12S1900, PGFL, PLGF, PlGF-2, SHGC-10760; placental growth factor; K16859 placenta growth factor (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Pathways in cancer (ko05200)	--	--	PDGF/VEGF domain	Placenta growth factor (Precursor) GN=PGF OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: placenta growth factor isoform X2 [Balaenoptera acutorostrata scammoni] 
ENSG00000119632(IFI27L2)	--	37.4873007	176	34.63620158	172	39.40890087	197	50.95670171	258	46.27710111	216	32.57050257	158	0.557527362	0.517214252	normal	0.910019774	0.304800366	normal	0.904926816	-0.323781302	normal	0.613538258	0.191282755	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced 6-16 family	Interferon alpha-inducible protein 27-like protein 2 (Precursor) GN=IFI27L2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: interferon alpha-inducible protein 27-like protein 2-like [Tursiops truncatus]
ENSG00000119636(BBOF1)	--	0.993211	63	0.936782	58	1.195379	51	1.702221316	81	1.27678	78	1.277574	79	0.952030149	0.32473876	normal	0.93565352	0.397039683	normal	0.825051361	0.608459748	normal	0.37960459	0.447000656	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4515)	Basal body-orientation factor 1 GN=CCDC176 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: basal body-orientation factor 1 [Galeopterus variegatus]
ENSG00000119638(NEK9)	--	22.66392101	2878	20.09235322	2640	19.23156	2583	26.01977826	3220	28.750387	3572	22.568831	2895	0.986336288	0.131095647	normal	0.771385427	0.414562737	normal	0.982948312	0.156137872	normal	0.173866269	0.23643897	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08857|0|hsa:91754|NEK9, NERCC, NERCC1, Nek8; NIMA-related kinase 9 (EC:2.7.11.1); K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)"	--	[S]	Function unknown	Protein kinase domain;; Regulator of chromosome condensation (RCC1) repeat;; Protein tyrosine kinase;; Regulator of chromosome condensation (RCC1) repeat	Serine/threonine-protein kinase Nek9 GN=NEK9 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: serine/threonine-protein kinase Nek9 [Equus przewalskii]
ENSG00000119640(ACYP1)	--	15.086887	123	17.97281	150	18.85853	158	14.674681	125	8.615053	70	9.478881	78	0.969129119	-0.007469927	normal	0.002334075	-1.104264803	down	0.006481972	-1.012591111	down	0.047676909	-0.681494568	normal	[C]	Energy production and conversion	--	"K01512|2.23933e-70|pon:100461549|ACYP1; acylphosphatase 1, erythrocyte (common) type; K01512 acylphosphatase [EC:3.6.1.7] (A)"	Pyruvate metabolism (ko00620)	[C]	Energy production and conversion	Acylphosphatase	Acylphosphatase-1 GN=ACYP1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: acylphosphatase-1 isoform 1 [Dasypus novemcinctus]
ENSG00000119650(IFT43)	--	24.32329093	299	22.135925	278	27.193633	345	21.579592	275	25.484736	313	21.553197	264	0.956606624	-0.150738112	normal	0.955952446	0.148887592	normal	0.788554696	-0.392377618	normal	0.687987147	-0.134796622	normal	--	--	Cellular Component: intraciliary transport particle A (GO:0030991);; 	--	--	--	--	Intraflagellar transport protein 43	Intraflagellar transport protein 43 homolog GN=IFT43 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: intraflagellar transport protein 43 homolog isoform 2 [Ovis aries]
ENSG00000119655(NPC2)	--	169.9563608	1981	169.3534209	2076	171.7883912	2226	236.7911116	2962	223.1598802	2790	358.1206253	4333	0.171644986	0.54916008	normal	0.775564452	0.404776941	normal	1.31E-06	0.952149101	normal	0.058683859	0.66277904	normal	--	--	--	"K13443|1.87671e-90|ptr:450192|NPC2, EPI-1; Niemann-Pick disease, type C2; K13443 Niemann-Pick C2 protein (A)"	Lysosome (ko04142)	[S]	Function unknown	ML domain	Epididymal secretory protein E1 (Precursor) GN=NPC2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: epididymal secretory protein E1 [Ovis aries] 
ENSG00000119661(DNAL1)	--	6.4554967	433	8.1308479	401	7.008378895	367	6.286940602	504	7.371691311	497	8.0645488	393	0.950853428	0.187607001	normal	0.902855782	0.28724243	normal	0.965631854	0.090098973	normal	0.457715981	0.192924999	normal	[S]	Function unknown	--	"K10411|7.93815e-133|ptr:739908|DNAL1; dynein, axonemal, light chain 1; K10411 dynein light chain 1, axonemal (A)"	Huntington's disease (ko05016)	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine-rich repeat;; Leucine rich repeat;; Leucine Rich Repeat	"Dynein light chain 1, axonemal GN=DNAL1 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: dynein light chain 1, axonemal [Tupaia chinensis]"
ENSG00000119669(IRF2BPL)	--	37.9119	2745	30.5085	2232	25.5257	1903	15.1653	1094	12.8504	936	12.6083	925	4.50E-14	-1.356777949	down	9.53E-12	-1.273806708	down	7.24E-08	-1.047820964	down	1.25E-06	-1.241406387	down	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Interferon regulatory factor 2-binding protein zinc finger	Interferon regulatory factor 2-binding protein-like GN=IRF2BPL OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: interferon regulatory factor 2-binding protein-like, partial [Camelus bactrianus]"
ENSG00000119673(ACOT2)	--	24.50903	628	21.591403	590	22.05801	579	25.217094	672	28.469835	740	27.436782	724	0.972597592	0.066706633	normal	0.890158749	0.304685141	normal	0.879345218	0.313401443	normal	0.279117579	0.228312849	normal	[R]	General function prediction only	--	"K01068|0|hsa:10965|ACOT2, CTE-IA, CTE1A, MTE1, PTE2, PTE2A, ZAP128; acyl-CoA thioesterase 2 (EC:3.1.2.2); K01068 acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] (A)"	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Ovarian steroidogenesis (ko04913)	--	--	BAAT / Acyl-CoA thioester hydrolase C terminal;; Acyl-CoA thioester hydrolase/BAAT N-terminal region;; Dienelactone hydrolase family	"Acyl-coenzyme A thioesterase 2, mitochondrial (Precursor) GN=ACOT2 OS=Homo sapiens (Human) PE=1 SV=6"	I	Lipid transport and metabolism	"PREDICTED: acyl-coenzyme A thioesterase 2, mitochondrial isoform X1 [Lipotes vexillifer]"
ENSG00000119681(LTBP2)	--	7.60473613	1273	5.619506641	826	8.07671025	1183	14.57964164	2195	16.96647944	2821	12.46411	1900	0.001125482	0.754454896	normal	0	1.74872598	up	0.01013123	0.674571245	normal	0.000563694	1.054258212	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K08023|0|hsa:4053|LTBP2, C14orf141, GLC3D, LTBP3, MSPKA, MSTP031, WMS3; latent transforming growth factor beta binding protein 2; K08023 latent transforming growth factor beta binding protein (A)"	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; TB domain;; EGF-like domain;; Coagulation Factor Xa inhibitory site;; EGF domain	Latent-transforming growth factor beta-binding protein 2 (Precursor) GN=LTBP2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: latent-transforming growth factor beta-binding protein 2 [Equus caballus]
ENSG00000119682(AREL1)	--	16.12902001	1417	16.43017902	1375	15.46843505	1365	18.16140685	1632	22.4596305	1933	18.064199	1474	0.972164223	0.172794354	normal	0.500714611	0.46954599	normal	0.979885354	0.102434897	normal	0.144980011	0.256201629	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	--	--	[OK]	"Posttranslational modification, protein turnover, chaperones;; Transcription"	HECT-domain (ubiquitin-transferase);; Filamin/ABP280 repeat	Apoptosis-resistant E3 ubiquitin protein ligase 1 GN=AREL1 OS=Homo sapiens (Human) PE=1 SV=3	KO	"Transcription;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: apoptosis-resistant E3 ubiquitin protein ligase 1 [Tupaia chinensis]
ENSG00000119684(MLH3)	--	10.27848412	1005	9.409862898	958	11.718477	1034	8.824275566	863	9.257662598	845	9.147734694	868	0.936646208	-0.250182049	normal	0.955630883	-0.202160806	normal	0.931545713	-0.26034453	normal	0.203395376	-0.239461222	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	"K08739|0|hsa:27030|MLH3, HNPCC7; mutL homolog 3; K08739 DNA mismatch repair protein MLH3 (A)"	Mismatch repair (ko03430)	[L]	"Replication, recombination and repair"	"MutL C terminal dimerisation domain;; DNA mismatch repair protein, C-terminal domain;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	DNA mismatch repair protein Mlh3 GN=MLH3 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA mismatch repair protein Mlh3 isoform X1 [Galeopterus variegatus]
ENSG00000119685(TTLL5)	--	10.59116012	926	11.15593696	965	12.52916079	1057	10.3796135	936	8.626536098	788	12.04917653	1047	0.978629314	-0.01531066	normal	0.886850072	-0.313215628	normal	0.980024456	-0.021973788	normal	0.636377246	-0.11006212	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16602|0|hsa:23093|TTLL5, CORD19, KIAA0998, STAMP; tubulin tyrosine ligase-like family, member 5; K16602 tubulin polyglutamylase TTLL5 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin polyglutamylase TTLL5 GN=TTLL5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin polyglutamylase TTLL5 isoform X2 [Pteropus alecto]
ENSG00000119688(ABCD4)	--	8.63510455	440	7.926347259	396	6.66770491	361	10.929345	500	11.84623731	552	11.4554058	541	0.958808322	0.153090609	normal	0.579190293	0.456259354	normal	0.177269748	0.573363325	normal	0.056985692	0.391171477	normal	[R]	General function prediction only	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05678|0|hsa:5826|ABCD4, ABC41, EST352188, MAHCJ, P70R, P79R, PMP69, PXMP1L; ATP-binding cassette, sub-family D (ALD), member 4; K05678 ATP-binding cassette, subfamily D (ALD), member 4 (A)"	ABC transporters (ko02010);; Peroxisome (ko04146)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC transporter transmembrane region 2;; ABC transporter	ATP-binding cassette sub-family D member 4 GN=ABCD4 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: ATP-binding cassette sub-family D member 4 isoform X1 [Tupaia chinensis]
ENSG00000119689(DLST)	--	50.419283	2654	46.000338	2393	52.70660926	2778	59.21486347	3120	59.42263015	3099	52.70203069	2773	0.977103777	0.202437221	normal	0.890439255	0.351360201	normal	0.989619075	-0.010884494	normal	0.342695525	0.179233893	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	K00658|0|pps:100983465|DLST; dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex); K00658 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase) [EC:2.3.1.61] (A)	Citrate cycle (TCA cycle) (ko00020);; Lysine degradation (ko00310);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	2-oxoacid dehydrogenases acyltransferase (catalytic domain);; Biotin-requiring enzyme	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (Precursor) GN=DLST OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"PREDICTED: dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial [Ailuropoda melanoleuca]"
ENSG00000119698(PPP4R4)	--	0.557646539	37	0.257465555	17	0.7942327	29	0.120167558	8	0.504453459	23	0.221171431	6	0.011757529	-2.042432002	normal	0.983302993	0.385131564	normal	0.075913324	-2.029317628	normal	0.157630454	-1.186339347	normal	--	--	--	"K15426|0|pon:100458115|PPP4R4; protein phosphatase 4, regulatory subunit 4; K15426 serine/threonine-protein phosphatase 4 regulatory subunit 4 (A)"	--	[T]	Signal transduction mechanisms	HEAT repeat;; HEAT repeats;; Vacuolar 14 Fab1-binding region	Serine/threonine-protein phosphatase 4 regulatory subunit 4 GN=PPP4R4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 4 [Orcinus orca]
ENSG00000119699(TGFB3)	--	0.600465839	21	0.636504524	23	0.510848034	20	0.2280125	11	0.408149655	13	0.369942835	12	0.962137029	-0.874022663	normal	0.962157383	-0.775879582	normal	0.977463343	-0.678425031	normal	0.259703384	-0.851130203	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K13377|0|ptr:453054|TGFB3; transforming growth factor, beta 3; K13377 transforming growth factor beta-3 (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Malaria (ko05144);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Chronic myeloid leukemia (ko05220);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Latency-associated peptide (Precursor) GN=TGFB3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: transforming growth factor beta-3 [Orycteropus afer afer]
ENSG00000119703(ZC2HC1C)	--	2.484952269	88	3.1032912	102	3.195513014	106	1.8122675	59	1.557890582	50	3.9312	99	0.802408585	-0.594847306	normal	0.0489989	-1.027769039	normal	0.967976256	-0.105300425	normal	0.222832775	-0.528474676	normal	--	--	--	--	--	--	--	zinc-finger of a C2HC-type	Zinc finger C2HC domain-containing protein 1C GN=ZC2HC1C OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: zinc finger C2HC domain-containing protein 1C [Ceratotherium simum simum]
ENSG00000119705(SLIRP)	--	183.464611	456	161.327796	415	180.52399	478	216.264869	609	193.587105	478	153.1191368	400	0.761904961	0.385449024	normal	0.951364065	0.181854853	normal	0.918574364	-0.264386397	normal	0.74029152	0.118202439	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial (Precursor) GN=SLIRP OS=Homo sapiens (Human) PE=1 SV=1"	A	RNA processing and modification	"PREDICTED: SRA stem-loop-interacting RNA-binding protein, mitochondrial isoform X1 [Leptonychotes weddellii]"
ENSG00000119707(RBM25)	--	31.962719	2974	37.10080156	3474	34.0427194	3250	35.37086344	3253	34.23158529	3227	33.58973576	3118	0.98843761	0.098485254	normal	0.987233485	-0.127773006	normal	0.989732518	-0.068077888	normal	0.895946735	-0.03627856	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: mRNA processing (GO:0006397);; 	K12822|3.42715e-161|ptr:453012|RBM25; RNA binding motif protein 25; K12822 RNA-binding protein 25 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"PWI domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 25 GN=RBM25 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	RBM25 protein [Bos taurus]
ENSG00000119711(ALDH6A1)	--	3.078591487	274	2.851778897	238	2.50497518	219	3.341524478	299	4.655065901	364	4.3248428	385	0.963624212	0.094629292	normal	0.235696943	0.58850564	normal	0.005939614	0.801408438	normal	0.031712987	0.49905347	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00140|0|ptr:467506|ALDH6A1; aldehyde dehydrogenase 6 family, member A1; K00140 malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; beta-Alanine metabolism (ko00410);; Inositol phosphate metabolism (ko00562);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)"	[EG]	Amino acid transport and metabolism;; Carbohydrate transport and metabolism	Aldehyde dehydrogenase family	"Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (Precursor) GN=ALDH6A1 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000119714(GPR68)	--	0.329201438	17	0.17177978	9	0.302245705	15	0.226037851	10	0.174926813	8	0.430789038	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08408|0|hsa:8111|GPR68, GPR12A, OGR1; G protein-coupled receptor 68; K08408 G protein-coupled receptor 68 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srw	Ovarian cancer G-protein coupled receptor 1 GN=GPR68 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ovarian cancer G-protein coupled receptor 1 [Oryctolagus cuniculus]
ENSG00000119715(ESRRB)	--	0.06621344	4	0	0	0.091210855	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08553|0|hsa:2103|ESRRB, DFNB35, ERR2, ERRb, ESRL2, NR3B2; estrogen-related receptor beta; K08553 estrogen-related receptor beta (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Steroid hormone receptor ERR2 GN=ESRRB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: steroid hormone receptor ERR2 isoform X1 [Condylura cristata] 
ENSG00000119718(EIF2B2)	--	15.03346921	663	13.79546538	611	13.88564692	608	18.20092801	771	17.5951725	795	16.2442785	689	0.956405298	0.1864887	normal	0.819988844	0.357578063	normal	0.958821594	0.171739705	normal	0.240456457	0.239320585	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: cellular metabolic process (GO:0044237);; 	"K03754|0|hsa:8892|EIF2B2, EIF-2Bbeta, EIF2B; eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa; K03754 translation initiation factor eIF-2B subunit beta (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Initiation factor 2 subunit family	Translation initiation factor eIF-2B subunit beta GN=EIF2B2 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: translation initiation factor eIF-2B subunit beta [Pantholops hodgsonii]
ENSG00000119720(NRDE2)	--	3.8480314	657	2.884761994	803	2.301412	634	2.337680011	649	3.217649479	743	2.357128855	655	0.973599115	-0.048393288	normal	0.967780821	-0.133203455	normal	0.973917996	0.038629966	normal	0.858519474	-0.054131676	normal	--	--	--	--	--	[S]	Function unknown	"NRDE-2, necessary for RNA interference;; Tetratricopeptide repeat"	Protein NRDE2 homolog GN=NRDE2 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: protein NRDE2 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000119723(COQ6)	--	11.06894	270	7.688924	199	8.404870012	269	8.823033593	260	7.2506291	210	9.3701446	253	0.964231527	-0.084788312	normal	0.96462986	0.055781667	normal	0.963337058	-0.09620245	normal	0.910106219	-0.050682936	normal	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Molecular Function: FAD binding (GO:0071949);; 	"K06126|0|hsa:51004|COQ6, CGI10, COQ10D6; coenzyme Q6 monooxygenase; K06126 ubiquinone biosynthesis monooxygenase Coq6 [EC:1.14.13.-] (A)"	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130)	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	FAD binding domain	Ubiquinone biosynthesis monooxygenase COQ6 GN=COQ6 OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: ubiquinone biosynthesis monooxygenase COQ6 [Ceratotherium simum simum]
ENSG00000119725(ZNF410)	--	30.88475512	1186	30.9074715	1208	30.1670974	1222	27.6476328	1095	29.78521111	1106	33.10353608	1299	0.972061208	-0.145808741	normal	0.971557385	-0.148501255	normal	0.97998717	0.079769943	normal	0.788536404	-0.067695661	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 410 GN=ZNF410 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 410 isoform X2 [Mustela putorius furo] 
ENSG00000119729(RHOQ)	--	30.413857	1546	36.346486	1859	28.3337	1421	25.446538	1304	24.835833	1270	33.679303	1769	0.932297763	-0.276129463	normal	0.121906448	-0.570559622	normal	0.911227874	0.307442248	normal	0.62496329	-0.17278493	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07194|2.15757e-150|tup:102499535|RHOQ; ras homolog family member Q; K07194 Ras homolog gene family, member Q (A)"	Insulin signaling pathway (ko04910)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoQ (Precursor) GN=RHOQ OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoQ [Ceratotherium simum simum]
ENSG00000119760(SUPT7L)	--	23.68663488	1337	23.10741791	1322	21.332053	1206	17.2840749	1030	16.975824	1012	22.05622813	1275	0.7043026	-0.406653222	normal	0.717934982	-0.40640634	normal	0.980237828	0.071888216	normal	0.176487952	-0.241329383	normal	--	--	--	K11316|0|ptr:459110|SUPT7L; suppressor of Ty 7 (S. cerevisiae)-like; K11316 STAGA complex 65 subunit gamma (A)	--	--	--	Bromodomain associated	STAGA complex 65 subunit gamma GN=SUPT7L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: STAGA complex 65 subunit gamma [Galeopterus variegatus]
ENSG00000119771(KLHL29)	--	2.741609975	276	1.924087027	187	2.525682118	254	2.543676452	254	3.019612487	300	2.381291294	236	0.956754957	-0.149802384	normal	0.13673386	0.656271346	normal	0.961600829	-0.113631028	normal	0.752206317	0.11883671	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10465|0|ptr:470324|KLHL29; kelch-like family member 29; K10465 kelch-like protein 29 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 29 GN=KLHL29 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 29 [Galeopterus variegatus]
ENSG00000119772(DNMT3A)	--	5.917955462	716	5.780204684	754	6.400105123	746	4.831403859	567	6.377047524	659	4.336364714	442	0.797320736	-0.366556852	normal	0.946954789	-0.215250404	normal	0.002821087	-0.761392137	normal	0.01586663	-0.431556057	normal	[L]	"Replication, recombination and repair"	--	"K17398|0|hsa:1788|DNMT3A, DNMT3A2, M.HsaIIIA, TBRS; DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37); K17398 DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37] (A)"	Cysteine and methionine metabolism (ko00270);; MicroRNAs in cancer (ko05206)	--	--	PWWP domain;; C-5 cytosine-specific DNA methylase	DNA (cytosine-5)-methyltransferase 3A GN=DNMT3A OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: DNA (cytosine-5)-methyltransferase 3A [Camelus bactrianus] 
ENSG00000119777(TMEM214)	--	32.545774	1849	31.82126757	1864	35.24910695	2066	28.24295277	1578	30.8548882	1772	30.517529	1741	0.947608062	-0.259246788	normal	0.982997084	-0.094371275	normal	0.952619731	-0.255011886	normal	0.259798243	-0.203535918	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2359)	Transmembrane protein 214 GN=TMEM214 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 214 isoform X1 [Camelus ferus]
ENSG00000119778(ATAD2B)	--	3.11497422	452	3.626344917	524	3.106420125	445	2.506275353	357	3.305630095	459	2.884351585	421	0.805360596	-0.369812659	normal	0.943285367	-0.211845393	normal	0.96688193	-0.087969141	normal	0.368965262	-0.220881332	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; Bromodomain;; AAA ATPase domain;; AAA domain (Cdc48 subfamily)	ATPase family AAA domain-containing protein 2B GN=ATAD2B OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ATPase family AAA domain-containing protein 2B isoform 1 [Orcinus orca]
ENSG00000119782(FKBP1B)	--	9.755792	157	6.300758	105	8.37198	137	1.962747	32	3.437577124	54	1.73210488	28	1.09E-12	-2.270988438	down	0.084775417	-0.961123412	normal	3.95E-11	-2.238660025	down	1.23E-07	-1.828383985	down	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09568|8.64784e-75|tup:102486181|FKBP1B; FK506 binding protein 1B, 12.6 kDa; K09568 FK506-binding protein 1 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase	Peptidyl-prolyl cis-trans isomerase FKBP1B GN=FKBP1B OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP1B isoform X1 [Eptesicus fuscus]
ENSG00000119787(ATL2)	--	33.34893115	1519	35.14779583	1632	32.88845462	1464	21.87421627	1025	22.31440253	1027	20.71928911	955	0.06204105	-0.597589145	normal	0.009162861	-0.688819164	normal	0.036202877	-0.623830266	normal	8.55E-06	-0.639530502	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K17339|0|hsa:64225|ATL2, ARL3IP2, ARL6IP2, atlastin2; atlastin GTPase 2; K17339 atlastin [EC:3.6.5.-] (A)"	--	[R]	General function prediction only	"Guanylate-binding protein, N-terminal domain;; Guanylate-binding protein, C-terminal domain"	Atlastin-2 GN=ATL2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: atlastin-2 isoform X1 [Oryctolagus cuniculus]
ENSG00000119801(YPEL5)	--	51.70759381	1586	51.52065131	1580	49.28616212	1488	36.07689426	1121	38.70289894	1186	36.98708977	1133	0.213145971	-0.530823658	normal	0.631298506	-0.434764993	normal	0.727921851	-0.401049497	normal	0.002428816	-0.457298407	normal	--	--	--	--	--	[R]	General function prediction only	"Yippee zinc-binding/DNA-binding /Mis18, centromere assembly"	Protein yippee-like 5 GN=YPEL5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	Protein yippee-like 5 [Myotis davidii]
ENSG00000119812(FAM98A)	--	29.38140947	1529	30.23921697	1609	30.20501705	1580	28.86921718	1519	30.087445	1557	24.33041444	1267	0.983716883	-0.040258213	normal	0.982778186	-0.068756241	normal	0.885433981	-0.326449806	normal	0.494958994	-0.141141775	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF2465)	Protein FAM98A GN=FAM98A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM98A [Ochotona princeps]
ENSG00000119820(YIPF4)	--	7.6367184	1523	8.364752	1667	7.6212342	1499	5.7716041	1159	6.9416588	1122	6.5406554	1309	0.649818839	-0.424375118	normal	0.080757592	-0.591948835	normal	0.963922993	-0.203606732	normal	0.008285232	-0.406273869	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Yip1 domain	Protein YIPF4 GN=YIPF4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein YIPF4 [Camelus ferus] 
ENSG00000119844(AFTPH)	--	16.27924	916	17.08839385	983	15.04270751	854	12.71717088	754	13.35835466	807	14.3806669	909	0.88556231	-0.311039203	normal	0.895451011	-0.305529575	normal	0.975442322	0.081612683	normal	0.395358978	-0.177319377	normal	--	--	--	--	--	--	--	"Clathrin-binding box of Aftiphilin, vesicle trafficking"	Aftiphilin GN=AFTPH OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: aftiphilin isoform X1 [Lipotes vexillifer]
ENSG00000119862(LGALSL)	--	6.498695297	377	6.291023881	366	7.779983844	450	4.355030196	253	4.464796	245	4.5822904	274	0.172908229	-0.603236543	normal	0.206097049	-0.597449674	normal	0.018747506	-0.720903386	normal	0.002135885	-0.648533183	normal	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	--	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-related protein GN=LGALSL OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: galectin-related protein [Camelus bactrianus] 
ENSG00000119865(CNRIP1)	--	1.220789329	35	1.636219452	47	0.890452238	25	1.402435051	41	1.010912853	29	1.63345621	47	0.979906777	0.189735885	normal	0.89340728	-0.689521498	normal	0.791320196	0.863763312	normal	0.913514069	0.107118628	normal	--	--	--	--	--	--	--	CB1 cannabinoid receptor-interacting protein 1	CB1 cannabinoid receptor-interacting protein 1 GN=CNRIP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CB1 cannabinoid receptor-interacting protein 1 [Physeter catodon]
ENSG00000119866(BCL11A)	--	0	0	0	0	0.030223471	2	0.463805139	6	0.299981626	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger"	B-cell lymphoma/leukemia 11A GN=BCL11A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: B-cell lymphoma/leukemia 11A [Mustela putorius furo] 
ENSG00000119878(CRIPT)	--	13.2346	352	18.1034	473	18.8994	488	15.0775	402	13.5616	359	16.0921	429	0.955757332	0.16013344	normal	0.706629285	-0.417744487	normal	0.949204186	-0.19355473	normal	0.568540284	-0.162702114	normal	--	--	--	--	--	[Z]	Cytoskeleton	Microtubule-associated protein CRIPT	Cysteine-rich PDZ-binding protein GN=CRIPT OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cysteine-rich PDZ-binding protein [Elephantulus edwardii]
ENSG00000119888(EPCAM)	--	0.574952195	16	0.684963886	19	0.773627367	22	1.620390053	45	3.281963	92	1.249502695	35	0.184389134	1.379030805	normal	1.60E-07	2.168204148	up	0.9524936	0.627114058	normal	0.097071099	1.572499399	normal	--	--	--	"K06737|0|ptr:459214|EPCAM, TACSTD1; epithelial cell adhesion molecule; K06737 tumor-associated calcium signal transducer 1 (A)"	--	--	--	Thyroglobulin type-1 repeat	Epithelial cell adhesion molecule (Precursor) GN=EPCAM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: epithelial cell adhesion molecule [Galeopterus variegatus]
ENSG00000119899(SLC17A5)	--	11.29342	576	15.35492	788	9.90606	501	12.06534003	625	12.69712	649	20.15454	1038	0.970236564	0.086732988	normal	0.895171624	-0.300766542	normal	4.26E-07	1.040403097	up	0.628904125	0.289707492	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12301|0|hsa:26503|SLC17A5, AST, ISSD, NSD, SD, SIALIN, SIASD, SLD; solute carrier family 17 (acidic sugar transporter), member 5; K12301 MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 5 (A)"	Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Sialin GN=SLC17A5 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sialin isoform X1 [Galeopterus variegatus]
ENSG00000119900(OGFRL1)	--	13.896351	1660	12.67219	1515	15.80807	1858	13.65146	1667	13.09738654	1570	16.74561	2020	0.984928411	-0.024738552	normal	0.983681555	0.0299908	normal	0.982866674	0.112225723	normal	0.89707097	0.042481033	normal	--	--	Molecular Function: receptor activity (GO:0004872);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Opioid growth factor receptor (OGFr) conserved region	Opioid growth factor receptor-like protein 1 GN=OGFRL1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: opioid growth factor receptor-like protein 1 [Orycteropus afer afer]
ENSG00000119906(SLF2)	--	10.58980176	1075	12.47636919	1436	11.7234181	1364	11.17265016	1181	10.06140586	1166	13.55558972	1518	0.976682006	0.10469725	normal	0.890636381	-0.321537964	normal	0.975582354	0.14588332	normal	0.958484282	-0.024092607	normal	--	--	--	--	--	--	--	"Family of unknown function, FAM178"	Protein FAM178A GN=FAM178A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM178A isoform X1 [Felis catus]
ENSG00000119912(IDE)	--	17.3086855	1632	18.64803782	1705	17.61684973	1618	21.79511332	2069	22.11738974	2103	21.03369583	1999	0.913357981	0.311199624	normal	0.93957828	0.281025765	normal	0.925634268	0.296525639	normal	0.071077757	0.295283388	normal	--	--	--	K01408|0|pps:100987046|IDE; insulin-degrading enzyme; K01408 insulysin [EC:3.4.24.56] (A)	Alzheimer's disease (ko05010)	[O]	"Posttranslational modification, protein turnover, chaperones"	Insulinase (Peptidase family M16);; Peptidase M16 inactive domain	Insulin-degrading enzyme GN=IDE OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: insulin-degrading enzyme isoform X1 [Lipotes vexillifer]
ENSG00000119915(ELOVL3)	--	0.3693	8	0	0	0.0457645	0	0.228652	5	0.357539	7	0.319776	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K10248|0|hsa:83401|ELOVL3, CIG-30, CIG30; ELOVL fatty acid elongase 3 (EC:2.3.1.199); K10248 elongation of very long chain fatty acids protein 3 [EC:2.3.1.199] (A)"	Fatty acid elongation (ko00062)	[I]	Lipid transport and metabolism	GNS1/SUR4 family	Elongation of very long chain fatty acids protein 3 GN=ELOVL3 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: elongation of very long chain fatty acids protein 3 [Galeopterus variegatus]
ENSG00000119917(IFIT3)	--	1.765226	92	2.80086	147	2.99751	157	3.377160325	179	3.00351	157	5.36839	284	0.015225406	0.918241515	normal	0.96478663	0.072797118	normal	0.007817952	0.840728222	normal	0.268941056	0.627376577	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3"	Interferon-induced protein with tetratricopeptide repeats 3 GN=IFIT3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: interferon-induced protein with tetratricopeptide repeats 3-like, partial [Ceratotherium simum simum]"
ENSG00000119919(NKX2-3)	--	0	0	0.116126375	4	0	0	0.029610523	1	0.05809789	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09343|5.55937e-165|hsa:159296|NKX2-3, CSX3, NK2.3, NKX2.3, NKX2C, NKX4-3; NK2 homeobox 3; K09343 homeobox protein Nkx-2.3 (A)"	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-2.3 GN=NKX2-3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: homeobox protein Nkx-2.3 [Canis lupus familiaris]
ENSG00000119922(IFIT2)	--	1.128369	72	1.955627	127	1.828723	114	1.936292	129	1.473764	91	2.875945	188	0.208975633	0.797592322	normal	0.809681135	-0.495314762	normal	0.189793764	0.706040978	normal	0.607937274	0.362438142	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Interferon-induced protein with tetratricopeptide repeats 2 GN=IFIT2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interferon-induced protein with tetratricopeptide repeats 2 [Bubalus bubalis]
ENSG00000119927(GPAM)	--	4.476292702	483	4.6816433	503	4.419708432	471	4.616313166	504	6.03784549	649	4.19702397	451	0.971189477	0.030473386	normal	0.839388999	0.34531736	normal	0.968780129	-0.070659198	normal	0.713453307	0.117255738	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K00629|0|hsa:57678|GPAM, GPAT, GPAT1; glycerol-3-phosphate acyltransferase, mitochondrial (EC:2.3.1.15); K00629 glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	"Glycerol-3-phosphate acyltransferase 1, mitochondrial (Precursor) GN=GPAM OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: glycerol-3-phosphate acyltransferase 1, mitochondrial isoform 1 [Odobenus rosmarus divergens] "
ENSG00000119929(CUTC)	--	22.12759	474	15.94764372	349	19.9072799	436	15.81654655	342	17.88582	383	12.6102	271	0.433604689	-0.499806222	normal	0.962155438	0.11222648	normal	0.034776203	-0.691256357	normal	0.177441801	-0.359617063	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: copper ion binding (GO:0005507);; Biological Process: copper ion homeostasis (GO:0055070);; 	K06201|0|ptr:100614738|CUTC; cutC copper transporter; K06201 copper homeostasis protein (A)	--	[P]	Inorganic ion transport and metabolism	CutC family	Copper homeostasis protein cutC homolog GN=CUTC OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: copper homeostasis protein cutC homolog isoform X1 [Sus scrofa]
ENSG00000119938(PPP1R3C)	--	3.589450426	148	4.638215	190	4.399096365	178	7.516151549	312	6.005874105	246	8.853742788	364	0.000105223	1.037537514	up	0.872635358	0.348786681	normal	6.88E-05	1.017597939	up	0.002353883	0.816621462	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: starch binding (GO:2001070);; 	"K07189|0|hsa:5507|PPP1R3C, PPP1R5; protein phosphatase 1, regulatory subunit 3C; K07189 protein phosphatase 1 regulatory subunit 3A/B/C/D/E (A)"	Insulin signaling pathway (ko04910)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Putative phosphatase regulatory subunit	Protein phosphatase 1 regulatory subunit 3C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 3C [Trichechus manatus latirostris]
ENSG00000119943(PYROXD2)	--	3.514711	165	3.756291994	164	3.7485499	166	6.087636	252	6.76503	297	5.465643	234	0.391810036	0.575758495	normal	0.009281526	0.829577585	normal	0.673960065	0.48330801	normal	0.013147009	0.640308997	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[H]	Coenzyme transport and metabolism	NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; Thi4 family;; Flavin containing amine oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; Glucose inhibited division protein A;; FAD binding domain	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 GN=PYROXD2 OS=Homo sapiens (Human) PE=2 SV=2	H	Coenzyme transport and metabolism	PREDICTED: pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000119946(CNNM1)	--	9.970694	1208	12.043559	1455	10.88466	1316	9.761635	1177	10.23657	1233	12.577541	1530	0.979904699	-0.06825045	normal	0.941204568	-0.259978987	normal	0.962709907	0.208857935	normal	0.914498188	-0.034679441	normal	[R]	General function prediction only	--	"K16302|0|hsa:26507|CNNM1, ACDP1, CLP-1; cyclin and CBS domain divalent metal cation transport mediator 1; K16302 metal transporter CNNM (A)"	--	[S]	Function unknown	Domain of unknown function DUF21;; CBS domain	Metal transporter CNNM1 GN=CNNM1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: metal transporter CNNM1 isoform X2 [Mustela putorius furo] 
ENSG00000119950(MXI1)	--	11.79657956	539	9.79953602	459	8.945435991	426	6.23927504	305	5.625753518	250	6.470279196	288	0.000710737	-0.849044389	normal	0.00052298	-0.893937723	normal	0.230052263	-0.570596426	normal	5.93E-05	-0.778036251	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09114|4.5917e-156|ggo:101130556|MXI1; max-interacting protein 1; K09114 MAX dimerization protein (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Max-interacting protein 1 GN=MXI1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: max-interacting protein 1 isoform 1 [Trichechus manatus latirostris]
ENSG00000119953(SMNDC1)	--	23.58080749	752	30.91945071	801	28.00642688	817	23.30289105	716	19.00917636	708	21.39333809	758	0.971364335	-0.101392997	normal	0.953413632	-0.199079347	normal	0.970803835	-0.116206297	normal	0.547384911	-0.140185207	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: mRNA processing (GO:0006397);; 	"K12839|2.80607e-150|hsa:10285|SMNDC1, SMNR, SPF30, TDRD16C; survival motor neuron domain containing 1; K12839 survival of motor neuron-related-splicing factor 30 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Survival motor neuron protein (SMN);; Tudor domain	Survival of motor neuron-related-splicing factor 30 GN=SMNDC1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: survival of motor neuron-related-splicing factor 30 isoform X2 [Canis lupus familiaris]
ENSG00000119965(C10orf88)	--	7.039951443	281	8.126127097	326	7.026448719	273	6.276983	250	6.028871	239	5.800732087	233	0.94673961	-0.198323775	normal	0.633683794	-0.466748158	normal	0.935923059	-0.23544908	normal	0.269706369	-0.307128537	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4506)	Uncharacterized protein C10orf88 GN=C10orf88 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C10orf88 homolog [Galeopterus variegatus]
ENSG00000119969(HELLS)	--	20.48254696	1619	21.70812665	1902	25.25066637	1873	18.78205905	1571	19.5663162	1565	21.39325809	1424	0.982979009	-0.074180598	normal	0.920848776	-0.302515501	normal	0.735330086	-0.403318507	normal	0.121057749	-0.26370075	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[K]	Transcription	SNF2 family N-terminal domain;; Helicase conserved C-terminal domain	Lymphoid-specific helicase OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: lymphoid-specific helicase isoform 1 [Ceratotherium simum simum]
ENSG00000119977(TCTN3)	--	33.3311335	1357	31.5055583	1289	32.698135	1330	35.2947808	1450	34.71752101	1425	25.9411907	1070	0.981964831	0.064729013	normal	0.977026195	0.123145649	normal	0.884533675	-0.32169823	normal	0.911866656	-0.033277555	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1619)	Tectonic-3 (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: tectonic-3 isoform 1 [Ceratotherium simum simum]
ENSG00000119979(FAM45A)	--	28.80405	998	24.95698	911	26.00253	897	27.04118967	1000	29.15048811	1025	29.51300451	1088	0.979250231	-0.027901074	normal	0.96879555	0.148441985	normal	0.92656596	0.269793619	normal	0.565946465	0.128765499	normal	--	--	--	--	--	--	--	Transport protein Avl9;; Stabilization of polarity axis	Protein FAM45A GN=FAM45A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	protein FAM45A [Bos taurus] 
ENSG00000119986(AVPI1)	--	64.0681	1751	78.5442	2182	79.5344	2239	65.93126	1811	53.14618	1448	118.2552	3265	0.985688877	0.017759876	normal	0.052414276	-0.612491047	normal	0.224287392	0.535635703	normal	0.954960941	0.06081961	normal	--	--	--	--	--	--	--	Thyroid cancer protein 1	Arginine vasopressin-induced protein 1 GN=AVPI1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: arginine vasopressin-induced protein 1 isoform X4 [Myotis brandtii] 
ENSG00000120008(WDR11)	--	15.48061338	1352	15.14011354	1326	14.96452713	1282	16.48894174	1424	18.654688	1620	18.174107	1583	0.982596304	0.043973039	normal	0.939802439	0.267210379	normal	0.917932247	0.295659139	normal	0.269600259	0.203671504	normal	--	--	--	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Nucleoporin Nup120/160"	WD repeat-containing protein 11 GN=WDR11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 11 isoform X1 [Tupaia chinensis]
ENSG00000120029(C10orf76)	--	8.949263895	668	9.164031712	642	9.08959089	682	9.951364624	734	9.557739256	707	8.245500237	621	0.970410397	0.104869547	normal	0.96797939	0.117446662	normal	0.964511228	-0.143137157	normal	0.934113939	0.028242049	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF1741)	UPF0668 protein C10orf76 GN=C10orf76 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0668 protein C10orf76 isoformX1 [Canis lupus familiaris] 
ENSG00000120049(KCNIP2)	--	0.660459405	32	1.136791495	35	1.16161517	32	0.368989565	15	0.4774553	26	1.230436323	40	0.827534567	-1.048773312	normal	0.970662628	-0.428699939	normal	0.975921416	0.300894928	normal	0.707950128	-0.307992784	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Kv channel-interacting protein 2 GN=KCNIP2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: Kv channel-interacting protein 2 isoform X1 [Condylura cristata]
ENSG00000120051(CFAP58)	--	0.105234202	9	0.1497363	13	0.138661291	11	0.116719254	10	0.043783386	3	0.159842464	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 147 GN=CCDC147 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 147 [Capra hircus]
ENSG00000120053(GOT1)	--	22.80948	894	20.68583	813	23.72415	925	16.78004	655	17.28663	668	21.07143	834	0.430189927	-0.478646765	normal	0.892401685	-0.304208397	normal	0.966267669	-0.157426235	normal	0.091024316	-0.30744508	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K14454|0|pps:100991554|GOT1; glutamic-oxaloacetic transaminase 1, soluble; K14454 aspartate aminotransferase, cytoplasmic [EC:2.6.1.1] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Cysteine and methionine metabolism (ko00270);; Arginine and proline metabolism (ko00330);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Phenylalanine, tyrosine and tryptophan biosynthesis (ko00400);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Aminotransferase class I and II	"Aspartate aminotransferase, cytoplasmic GN=GOT1 OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: aspartate aminotransferase, cytoplasmic [Panthera tigris altaica] "
ENSG00000120054(CPN1)	--	0	0	0.0547488	2	0	0	0	0	0	0	0.027269	1	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	"K01292|0|hsa:1369|CPN1, CPN, SCPN; carboxypeptidase N, polypeptide 1 (EC:3.4.17.3); K01292 carboxypeptidase N catalytic subunit [EC:3.4.17.3] (A)"	--	[R]	General function prediction only	Zinc carboxypeptidase;; Carboxypeptidase regulatory-like domain;; Protein of unknown function (DUF2817)	Carboxypeptidase N catalytic chain (Precursor) GN=CPN1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carboxypeptidase N catalytic chain [Camelus ferus] 
ENSG00000120055(C10orf95)	--	1.31674	25	0.750421	15	1.83353	37	0.504573	10	1.11069	21	0.765758	15	0.836900891	-1.22966169	normal	0.983931825	0.427447027	normal	0.548286134	-1.22952777	normal	0.34017531	-0.761869791	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C10orf95 GN=C10orf95 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC102167427 isoform X1 [Sus scrofa] 
ENSG00000120057(SFRP5)	--	1.80464	55	0.916445	29	0.74411	23	1.20716	37	1.33954	40	1.29955	40	0.914427651	-0.582756024	normal	0.966818887	0.423642797	normal	0.906229214	0.752148653	normal	0.913514069	0.107167204	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K02222|0|ggo:101125988|SFRP5; secreted frizzled-related protein 5; K02222 secreted frizzled-related protein 5 (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Fz domain;; UNC-6/NTR/C345C module	Secreted frizzled-related protein 5 (Precursor) GN=SFRP5 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: secreted frizzled-related protein 5 [Bubalus bubalis]
ENSG00000120063(GNA13)	--	30.83851627	2371	31.59649111	2447	29.09538031	2201	31.4782127	2437	32.75150724	2505	31.87032535	2445	0.988476974	0.008772718	normal	0.988389357	0.012362393	normal	0.982287193	0.143290428	normal	0.837911126	0.052395461	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04639|0|mcf:102127819|GNA13; guanine nucleotide binding protein (G protein), alpha 13; K04639 guanine nucleotide-binding protein subunit alpha-13 (A)"	cGMP-PKG signaling pathway (ko04022);; Sphingolipid signaling pathway (ko04071);; Vascular smooth muscle contraction (ko04270);; Platelet activation (ko04611);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family	Guanine nucleotide-binding protein subunit alpha-13 GN=GNA13 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit alpha-13 [Trichechus manatus latirostris]
ENSG00000120068(HOXB8)	--	16.87643056	874	13.11296783	976	16.13691693	893	25.18060405	1364	23.069877	1334	20.0514445	1312	0.049785222	0.610440794	normal	0.644858954	0.428808653	normal	0.171126989	0.545976831	normal	0.000451906	0.526456638	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09308|6.5132e-151|ssc:100627661|HOXB8; homeobox B8; K09308 homeobox protein HoxB/C/D8 (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-B8 GN=HOXB8 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein Hox-B8 isoform X1 [Bubalus bubalis]
ENSG00000120071(KANSL1)	--	15.53208309	1409	18.58066073	1665	16.22590613	1442	14.88642637	1409	15.91746021	1453	18.8465987	1764	0.983085774	-0.03079868	normal	0.961949995	-0.217702168	normal	0.93211098	0.282219926	normal	0.971576238	0.01404679	normal	--	--	--	"K18400|0|hsa:284058|KANSL1, CENP-36, KDVS, KIAA1267, MSL1v1, NSL1, hMSL1v1; KAT8 regulatory NSL complex subunit 1; K18400 KAT8 regulatory NSL complex subunit 1 (A)"	--	--	--	PEHE domain	KAT8 regulatory NSL complex subunit 1 GN=KANSL1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: KAT8 regulatory NSL complex subunit 1 isoformX1 [Equus caballus]
ENSG00000120088(CRHR1)	--	6.705148048	376	7.204258347	402	7.1294203	396	6.280010021	355	5.886484252	329	5.7674831	325	0.962872176	-0.11326945	normal	0.886641157	-0.309246085	normal	0.901086874	-0.292118639	normal	0.360290855	-0.239961587	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04578|0|hsa:1394|CRHR1, CRF-R, CRF-R-1, CRF-R1, CRF1, CRFR-1, CRFR1, CRH-R-1, CRH-R1, CRHR, CRHR1L; corticotropin releasing hormone receptor 1; K04578 corticotropin releasing hormone receptor 1 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Long-term depression (ko04730)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Corticotropin-releasing factor receptor 1 (Precursor) GN=CRHR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: corticotropin-releasing factor receptor 1 isoform X1 [Tupaia chinensis] 
ENSG00000120129(DUSP1)	--	79.3234	2492	92.9916	2966	119.445	3829	101.703	3197	102.451	3216	162.622	5136	0.915644375	0.328403269	normal	0.988242445	0.095275591	normal	0.794394407	0.415244005	normal	0.594039789	0.295318159	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K04459|0|ptr:471742|DUSP1; dual specificity phosphatase 1; K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 1 GN=DUSP1 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 1 [Ailuropoda melanoleuca] 
ENSG00000120137(PANK3)	--	18.609243	2871	20.00883633	3086	19.054464	2877	17.393897	2713	17.854373	2752	19.446157	3005	0.986717931	-0.112434635	normal	0.979782712	-0.186587258	normal	0.989465959	0.054480305	normal	0.725510235	-0.081669319	normal	[H]	Coenzyme transport and metabolism	Molecular Function: pantothenate kinase activity (GO:0004594);; Molecular Function: ATP binding (GO:0005524);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; 	K09680|0|mcf:102123167|PANK3; pantothenate kinase 3; K09680 type II pantothenate kinase [EC:2.7.1.33] (A)	Pantothenate and CoA biosynthesis (ko00770)	[H]	Coenzyme transport and metabolism	Fumble	Pantothenate kinase 3 GN=PANK3 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: pantothenate kinase 3 [Tupaia chinensis]
ENSG00000120149(MSX2)	--	3.214591148	109	3.536717	122	2.960909112	104	4.786926968	169	6.999840857	219	4.165627105	148	0.526683775	0.595078722	normal	0.033033471	0.81498255	normal	0.778736354	0.494662944	normal	0.035300492	0.656487993	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09341|8.15082e-142|pps:100987321|MSX2; msh homeobox 2; K09341 homeobox protein MSX (A)	HTLV-I infection (ko05166)	[R]	General function prediction only	Homeobox domain	Homeobox protein MSX-2 GN=MSX2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein MSX-2 [Galeopterus variegatus]
ENSG00000120156(TEK)	--	0.036844837	1	0.024483296	2	0.01248374	0	0.048885735	4	0.051277394	4	0.053025598	5	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);; 	"K05121|0|hsa:7010|TEK, CD202B, TIE-2, TIE2, VMCM, VMCM1; TEK tyrosine kinase, endothelial (EC:2.7.10.1); K05121 endothelial-specific receptor tyrosine kinase [EC:2.7.10.1] (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; HIF-1 signaling pathway (ko04066);; PI3K-Akt signaling pathway (ko04151);; Rheumatoid arthritis (ko05323)	[T]	Signal transduction mechanisms	"Protein tyrosine kinase;; Tie-2 Ig-like domain 1;; Protein kinase domain;; Fibronectin type III domain;; Interferon-alpha/beta receptor, fibronectin type III"	Angiopoietin-1 receptor (Precursor) GN=TEK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: angiopoietin-1 receptor [Oryctolagus cuniculus]
ENSG00000120158(RCL1)	--	13.43632124	482	14.84037168	511	12.23626718	428	14.59292306	521	16.5681727	592	17.40532145	614	0.968719611	0.081169072	normal	0.951343843	0.190323655	normal	0.351182926	0.510821592	normal	0.235178842	0.260420043	normal	[A]	RNA processing and modification	--	K11108|0|cjc:100412539|RCL1; RNA terminal phosphate cyclase-like 1; K11108 RNA 3'-terminal phosphate cyclase-like protein (A)	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	"RNA 3'-terminal phosphate cyclase;; RNA 3'-terminal phosphate cyclase (RTC), insert domain"	RNA 3'-terminal phosphate cyclase-like protein GN=RCL1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: RNA 3'-terminal phosphate cyclase-like protein [Oryctolagus cuniculus]
ENSG00000120159(CAAP1)	--	13.43291	507	10.54979966	454	14.69184831	529	17.57920557	626	18.794453	629	14.709317	581	0.914059094	0.272600115	normal	0.594144064	0.447669217	normal	0.965066688	0.126633454	normal	0.183394884	0.280062379	normal	--	--	--	--	--	--	--	Caspase activity and apoptosis inhibitor 1	Caspase activity and apoptosis inhibitor 1 GN=CAAP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: caspase activity and apoptosis inhibitor 1 [Odobenus rosmarus divergens]
ENSG00000120162(MOB3B)	--	1.964972	203	1.577774	162	2.294924	233	8.34345	865	9.47947	978	6.095236	631	0	2.052213186	up	0	2.561353585	up	9.35E-12	1.423175191	up	9.19E-10	2.027211802	up	--	--	--	"K06685|1.09602e-162|ptr:743792|MOB3B, MOBKL2B; MOB kinase activator 3B; K06685 MOB kinase activator 1 (A)"	Hippo signaling pathway (ko04390)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mob1/phocein family	MOB kinase activator 3B GN=MOB3B OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	MOB kinase activator 3B [Bos taurus] 
ENSG00000120211(INSL4)	--	2.7355468	89	5.161693	167	3.412549483	110	3.998295447	128	5.07144	162	6.904655	225	0.826041729	0.486399538	normal	0.964770328	-0.06468607	normal	0.000968855	1.014179077	up	0.424413392	0.472829539	normal	--	--	--	"K05255|9.67043e-84|hsa:3641|INSL4, EPIL, PLACENTIN; insulin-like 4 (placenta); K05255 relaxin (A)"	--	--	--	--	Early placenta insulin-like peptide A chain (Precursor) GN=INSL4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: early placenta insulin-like peptide isoform X1 [Oryctolagus cuniculus]
ENSG00000120215(MLANA)	--	0.367482813	13	0.622228093	22	0.310105882	10	0.249605689	9	0.245858988	8	0.336024	13	--	--	--	0.83873928	-1.324585586	normal	--	--	--	--	--	--	--	--	Cellular Component: melanosome (GO:0042470);; 	K17303|1.8383e-69|ptr:464984|MLANA; melan-A; K17303 melanoma antigen recognized by T-cells 1 (A)	--	--	--	Protein melan-A	Melanoma antigen recognized by T-cells 1 GN=MLANA OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: melanoma antigen recognized by T-cells 1 [Panthera tigris altaica]
ENSG00000120217(CD274)	--	0.294504477	18	0.228847562	14	0.310338648	18	1.835637989	113	1.590427058	97	0.910442755	56	3.82E-11	2.522152131	up	1.89E-10	2.646674716	up	0.015246788	1.551626159	normal	2.75E-05	2.38861148	up	--	--	--	K06745|0|ptr:464981|CD274; CD274 molecule; K06745 programmed cell death 1 ligand 1 (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Programmed cell death 1 ligand 1 (Precursor) GN=CD274 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: programmed cell death 1 ligand 1 [Oryctolagus cuniculus]
ENSG00000120251(GRIA2)	--	0.089123211	1	0.01689342	1	0	0	0	0	0	0	0.034131596	2	--	--	--	--	--	--	--	--	--	--	--	--	[ET]	Amino acid transport and metabolism;; Signal transduction mechanisms	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	K05198|0|ggo:101146262|GRIA2; glutamate receptor 2 isoform 1; K05198 glutamate receptor 2 (A)	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Receptor family ligand binding region;; Ligated ion channel L-glutamate- and glycine-binding site;; Bacterial extracellular solute-binding proteins, family 3"	Glutamate receptor 2 (Precursor) GN=GRIA2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	glutamate receptor 2 isoform 2 precursor [Equus caballus] 
ENSG00000120253(NUP43)	--	15.77101866	964	16.65149785	1008	16.69011387	1003	18.22204518	1097	15.67276791	942	16.57711579	1015	0.968939258	0.155393935	normal	0.972883587	-0.118938597	normal	0.979691616	0.00885341	normal	0.962333677	0.016345302	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K14305|0|hsa:348995|NUP43, bA350J20.1, p42; nucleoporin 43kDa; K14305 nuclear pore complex protein Nup43 (A)"	RNA transport (ko03013)	[Y]	Nuclear structure	"WD domain, G-beta repeat"	Nucleoporin Nup43 GN=NUP43 OS=Homo sapiens (Human) PE=1 SV=1	Y	Nuclear structure	PREDICTED: nucleoporin Nup43 [Lipotes vexillifer]
ENSG00000120254(MTHFD1L)	--	18.78367354	1244	17.56999201	1162	17.09760179	1162	22.82304575	1448	20.6099073	1343	24.31342548	1542	0.966898004	0.188027458	normal	0.965652556	0.18719591	normal	0.734529528	0.399448529	normal	0.136479803	0.259165305	normal	[F]	Nucleotide transport and metabolism	Molecular Function: formate-tetrahydrofolate ligase activity (GO:0004329);; Molecular Function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488);; Molecular Function: ATP binding (GO:0005524);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13402|0|hsa:25902|MTHFD1L, FTHFSDC1, MTC1THFS, dJ292B18.2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (EC:6.3.4.3); K13402 monofunctional C1-tetrahydrofolate synthase, mitochondrial [EC:6.3.4.3] (A)"	One carbon pool by folate (ko00670)	[H]	Coenzyme transport and metabolism	"Formate--tetrahydrofolate ligase;; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain;; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial (Precursor) GN=MTHFD1L OS=Homo sapiens (Human) PE=1 SV=1"	H	Coenzyme transport and metabolism	"PREDICTED: monofunctional C1-tetrahydrofolate synthase, mitochondrial [Trichechus manatus latirostris]"
ENSG00000120256(LRP11)	--	29.56058	1364	29.409146	1357	32.121789	1474	37.471454	1804	39.3191146	1831	46.58503248	2109	0.813182491	0.372157914	normal	0.724494805	0.410389466	normal	0.30885391	0.508093071	normal	0.004019673	0.432800728	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	MANEC domain;; Low-density lipoprotein receptor domain class A	Low-density lipoprotein receptor-related protein 11 (Precursor) GN=LRP11 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 11 [Odobenus rosmarus divergens]
ENSG00000120262(CCDC170)	--	0.223543	25	0.116329	13	0.115822	12	0.133824	15	0.329596	37	0.21338	24	0.965758442	-0.710832645	normal	0.347560089	1.388154586	normal	0.945267363	0.909338618	normal	0.533501444	0.583714975	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 170 GN=CCDC170 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 170 isoform X1 [Tupaia chinensis]
ENSG00000120265(PCMT1)	--	35.03027795	974	32.26882	916	35.276327	1009	40.050067	1122	34.827049	979	34.6639831	980	0.965847846	0.172992337	normal	0.976271554	0.074415854	normal	0.978604617	-0.050287481	normal	0.799688924	0.066332466	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K00573|0|hsa:5110|PCMT1, PIMT; protein-L-isoaspartate (D-aspartate) O-methyltransferase (EC:2.1.1.77); K00573 protein-L-isoaspartate(D-aspartate) O-methyltransferase [EC:2.1.1.77] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family	Protein-L-isoaspartate(D-aspartate) O-methyltransferase GN=PCMT1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-L-isoaspartate(D-aspartate) O-methyltransferase isoform X1 [Galeopterus variegatus]
ENSG00000120278(PLEKHG1)	--	0.506531725	68	0.439913335	61	0.398681732	55	0.497569199	35	0.353685686	47	0.616689395	50	0.366664128	-0.958275864	normal	0.951501345	-0.38662301	normal	0.975938865	-0.141706771	normal	0.368620768	-0.49951348	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	--	--	RhoGEF domain	Pleckstrin homology domain-containing family G member 1 GN=PLEKHG1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family G member 1 [Ceratotherium simum simum]
ENSG00000120279(MYCT1)	--	0	0	0	0	0	0	0.114213705	2	0.071946011	2	0.0463916	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Myc target protein 1	Myc target protein 1 GN=MYCT1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: myc target protein 1 [Ceratotherium simum simum]
ENSG00000120306(CYSTM1)	--	75.8065	1009	81.6681	1147	68.5805	924	84.5562	1080	73.8242	976	88.3372	1157	0.978345268	0.067174	normal	0.938212673	-0.253975426	normal	0.886865536	0.31567004	normal	0.890794781	0.039662888	normal	--	--	--	--	--	--	--	Cysteine-rich TM module stress tolerance	Cysteine-rich and transmembrane domain-containing protein 1 GN=CYSTM1 OS=Homo sapiens (Human) PE=1 SV=1	--	--	--
ENSG00000120314(WDR55)	--	9.89951	832	6.99851	597	9.24131	783	9.92065	830	9.50514	790	8.24614	692	0.976924189	-0.034241147	normal	0.77155667	0.38185186	normal	0.957134531	-0.18614901	normal	0.903207025	0.042310107	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 55 GN=WDR55 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 55 [Ailuropoda melanoleuca] 
ENSG00000120318(ARAP3)	--	3.929757213	447	3.901106939	449	3.6775314	429	3.31564336	373	4.336185067	494	3.864381655	439	0.900104074	-0.290835299	normal	0.96391363	0.115996477	normal	0.970224105	0.0248652	normal	0.90779029	-0.041536228	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K12490|0|hsa:64411|ARAP3, CENTD3, DRAG1; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3; K12490 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 (A)"	Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Endocytosis (ko04144)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	RhoGAP domain;; Putative GTPase activating protein for Arf;; PH domain;; SAM domain (Sterile alpha motif);; Ras association (RalGDS/AF-6) domain;; SAM domain (Sterile alpha motif);; Pleckstrin homology domain;; PH domain	"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 GN=ARAP3 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3 [Ceratotherium simum simum]"
ENSG00000120322(PCDHB8)	--	0.794202782	61	1.674212914	100	0.769652599	55	0.8599963	54	0.76857918	60	0.704097344	49	0.972037698	-0.201289316	normal	0.479083262	-0.743711402	normal	0.975033389	-0.169986591	normal	0.434287535	-0.428294569	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56128|PCDHB8, PCDH-BETA8, PCDH3I; protocadherin beta 8; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like;; Putative flagellar system-associated repeat	Protocadherin beta-8 (Precursor) GN=PCDHB8 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protocadherin beta-8 [Galeopterus variegatus]
ENSG00000120324(PCDHB10)	--	0.0561099	3	0.147899	8	0.109458	5	0.0185757	1	0.0903686	4	0.166105	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56126|PCDHB10, PCDH-BETA10, PCHB10; protocadherin beta 10; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-10 (Precursor) GN=PCDHB10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protocadherin beta-10-like isoform X1 [Ursus maritimus]
ENSG00000120328(PCDHB12)	--	0.05599413	3	0.106695849	4	0.027977859	0	0.064494175	4	0	0	0.0157376	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56124|PCDHB12, PCDH-BETA12; protocadherin beta 12; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-12 (Precursor) GN=PCDHB12 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin beta-11 [Equus przewalskii]
ENSG00000120329(SLC25A2)	--	0.0448877	1	0.0439099	1	0	0	0.0438819	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15101|0|hsa:83884|SLC25A2, ORC2, ORNT2; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2; K15101 solute carrier family 25 (mitochondrial ornithine transporter) member 2/15 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial ornithine transporter 2 GN=SLC25A2 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: mitochondrial ornithine transporter 2 [Galeopterus variegatus]
ENSG00000120333(MRPS14)	--	8.53559	297	7.90849	277	9.12911	314	7.30749	258	7.95834	276	9.89951	346	0.93578108	-0.232631562	normal	0.966168566	-0.026499333	normal	0.960120562	0.131114268	normal	0.941204269	-0.033191008	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02954|4.28113e-89|ptr:739735|MRPS14; mitochondrial ribosomal protein S14; K02954 small subunit ribosomal protein S14 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S14p/S29e	"28S ribosomal protein S14, mitochondrial OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S14, mitochondrial [Camelus ferus] "
ENSG00000120334(CENPL)	--	6.137386	193	5.07524	164	6.254531565	189	7.166375263	218	5.1144	161	5.857607094	188	0.958399317	0.143817353	normal	0.965481725	-0.047618501	normal	0.966993596	-0.015818109	normal	0.956592571	0.032804185	normal	--	--	--	"K11504|0|hsa:91687|CENPL, C1orf155, CENP-L, dJ383J4.3; centromere protein L; K11504 centromere protein L (A)"	--	--	--	Kinetochore complex Sim4 subunit Fta1	Centromere protein L GN=CENPL OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centromere protein L [Orcinus orca] 
ENSG00000120341(SEC16B)	--	0.419065472	37	0.316608743	27	0.749740654	66	0.544945988	47	0.696966048	61	0.604892124	53	0.972674388	0.303115098	normal	0.229926096	1.111956855	normal	0.96015837	-0.316652203	normal	0.684497972	0.289261376	normal	--	--	--	--	--	[K]	Transcription	Sec23-binding domain of Sec16;; Vesicle coat trafficking protein Sec16 mid-region	Protein transport protein Sec16B GN=SEC16B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec16B [Ceratotherium simum simum]
ENSG00000120370(GORAB)	--	4.174444	175	4.993878536	213	4.101031	172	4.47016	191	4.487301392	189	4.101041	176	0.963887792	0.094590409	normal	0.948982747	-0.192442228	normal	0.967055344	0.024661069	normal	0.95908328	-0.032012685	normal	--	--	--	--	--	--	--	--	RAB6-interacting golgin GN=GORAB OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RAB6-interacting golgin [Galeopterus variegatus]
ENSG00000120437(ACAT2)	--	25.5219	1475	25.1893	1469	33.3044	1932	11.6487	678	9.74055	560	21.3844	1241	2.34E-09	-1.15037546	down	9.79E-14	-1.410316024	down	0.020165385	-0.646246967	normal	0.008671883	-0.994777057	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K00626|0|hsa:39|ACAT2; acetyl-CoA acetyltransferase 2 (EC:2.3.1.9); K00626 acetyl-CoA C-acetyltransferase [EC:2.3.1.9] (A)	"Fatty acid degradation (ko00071);; Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Pyruvate metabolism (ko00620);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; Terpenoid backbone biosynthesis (ko00900);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212);; Fat digestion and absorption (ko04975)"	[I]	Lipid transport and metabolism	"Thiolase, N-terminal domain;; Thiolase, C-terminal domain;; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal"	"Acetyl-CoA acetyltransferase, cytosolic GN=ACAT2 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: acetyl-CoA acetyltransferase, cytosolic [Ceratotherium simum simum]"
ENSG00000120438(TCP1)	--	113.978459	4630	102.2187925	4293	120.6736543	4946	124.277894	5139	112.9585461	4505	98.334219	3922	0.990997958	0.119605512	normal	0.992128028	0.048097835	normal	0.922690312	-0.342846149	normal	0.840331581	-0.053675443	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	K09493|0|ptr:739754|TCP1; t-complex 1; K09493 T-complex protein 1 subunit alpha (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit alpha GN=TCP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: T-complex protein 1 subunit alpha [Galeopterus variegatus]
ENSG00000120440(TTLL2)	--	0	0	0	0	0	0	0.0257315	1	0.0252095	0	0.102811	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16600|0|hsa:83887|TTLL2, C6orf104, NYD-TSPG, dJ366N23.3; tubulin tyrosine ligase-like family, member 2; K16600 tubulin polyglutamylase TTLL2 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Probable tubulin polyglutamylase TTLL2 GN=TTLL2 OS=Homo sapiens (Human) PE=5 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable tubulin polyglutamylase TTLL2 [Leptonychotes weddellii]
ENSG00000120451(SNX19)	--	14.51958984	1791	14.93336536	1813	16.54618666	1934	13.32399988	1645	15.24261263	1747	15.507703	1853	0.977082818	-0.153372668	normal	0.983793596	-0.074862255	normal	0.985018654	-0.069960462	normal	0.654520284	-0.099118475	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17930|0|pps:100991184|SNX19; sorting nexin 19; K17930 sorting nexin-19 (A)	--	--	--	PXA domain;; Sorting nexin C terminal;; PX domain	Sorting nexin-19 GN=SNX19 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-19 isoform X1 [Ursus maritimus]
ENSG00000120457(KCNJ5)	--	0.311705539	9	0.0440901	1	0.03051481	3	0	0	0.0432545	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04999|0|hsa:3762|KCNJ5, CIR, GIRK4, KATP1, KIR3.4, LQT13; potassium inwardly-rectifying channel, subfamily J, member 5; K04999 potassium inwardly-rectifying channel subfamily J member 5 (A)"	Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Estrogen signaling pathway (ko04915);; Oxytocin signaling pathway (ko04921);; Morphine addiction (ko05032)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	G protein-activated inward rectifier potassium channel 4 GN=KCNJ5 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: G protein-activated inward rectifier potassium channel 4 isoform X1 [Mustela putorius furo] 
ENSG00000120458(MSANTD2)	--	4.210842411	174	3.529167259	166	4.615193469	193	5.278907254	230	5.86635124	266	4.98077148	234	0.860519521	0.368873605	normal	0.174295327	0.65406895	normal	0.926416265	0.267708447	normal	0.132076076	0.432937273	normal	--	--	--	--	--	--	--	Myb/SANT-like DNA-binding domain	Myb/SANT-like DNA-binding domain-containing protein 2 GN=MSANTD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: myb/SANT-like DNA-binding domain-containing protein 2 isoform X1 [Loxodonta africana]
ENSG00000120471(TP53AIP1)	--	0.0471246	2	0.0175694	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13773|1.81564e-70|hsa:63970|TP53AIP1, P53AIP1; tumor protein p53 regulated apoptosis inducing protein 1; K13773 p53-regulated apoptosis-inducing protein 1 (A)"	p53 signaling pathway (ko04115)	--	--	p53-regulated apoptosis-inducing protein 1	p53-regulated apoptosis-inducing protein 1 GN=TP53AIP1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000120509(PDZD11)	--	44.82527	675	40.6132	601	49.8466	730	52.10304	788	51.33694	752	44.30387	668	0.955166078	0.192070944	normal	0.893725677	0.301262206	normal	0.966567437	-0.136045072	normal	0.639329075	0.117021443	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain	PDZ domain-containing protein 11 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: PDZ domain-containing protein 11 isoform X1 [Tupaia chinensis] 
ENSG00000120519(SLC10A7)	--	1.789294384	71	1.210897809	46	2.332393088	63	3.005990987	104	3.323185663	120	3.071096953	98	0.847017922	0.510681851	normal	0.000471811	1.333777385	up	0.739048243	0.61716944	normal	0.035821004	0.818018197	normal	[R]	General function prediction only	Cellular Component: membrane (GO:0016020);; 	"K14347|0|mcf:102143006|SLC10A7; solute carrier family 10, member 7; K14347 solute carrier family 10 (sodium/bile acid cotransporter), member 7 (A)"	--	[R]	General function prediction only	SBF-like CPA transporter family (DUF4137);; Sodium Bile acid symporter family	Sodium/bile acid cotransporter 7 GN=SLC10A7 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/bile acid cotransporter 7 isoform X1 [Bison bison bison]
ENSG00000120526(NUDCD1)	--	22.66888	890	20.57482	827	25.65131	1013	26.40741	1079	23.00203	949	19.457	832	0.939689658	0.246598267	normal	0.96198693	0.176792224	normal	0.907713278	-0.291788706	normal	0.876307067	0.045452761	normal	--	--	--	--	--	[S]	Function unknown	CS domain	NudC domain-containing protein 1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nudC domain-containing protein 1 [Galeopterus variegatus]
ENSG00000120533(ENY2)	--	55.17467309	949	65.421107	1116	67.6812	1089	84.6726337	1344	70.713706	1231	78.212496	1270	0.456626899	0.470577862	normal	0.97535794	0.11991242	normal	0.957561927	0.213258616	normal	0.132334452	0.264473262	normal	--	--	--	K11368|6.6812e-58|umr:103661561|ENY2; enhancer of yellow 2 homolog (Drosophila); K11368 enhancer of yellow 2 transcription factor (A)	--	[K]	Transcription	Transcription factor e(y)2	Transcription and mRNA export factor ENY2 {ECO:0000255|HAMAP-Rule:MF_03046} OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	Enhancer of yellow 2 transcription factor like protein [Myotis davidii]
ENSG00000120539(MASTL)	--	14.91569	911	16.99296	1006	17.36524	1023	13.415585	806	13.690131	810	13.66985452	833	0.953263586	-0.207131777	normal	0.862783037	-0.333503101	normal	0.896049024	-0.3042099	normal	0.116258856	-0.284615242	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16309|0|hsa:84930|MASTL, GREATWALL, GW, GWL, MAST-L, THC2, hGWL; microtubule associated serine/threonine kinase-like (EC:2.7.11.1); K16309 serine/threonine-protein kinase greatwall [EC:2.7.11.1] (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase greatwall GN=MASTL OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase greatwall isoform 1 [Ceratotherium simum simum]
ENSG00000120549(KIAA1217)	--	2.563991691	415	2.982439838	429	3.280796178	461	3.63911991	550	3.69509215	550	3.7060396	565	0.789268344	0.374281006	normal	0.853565209	0.335979063	normal	0.905122164	0.284348734	normal	0.11673534	0.330517357	normal	--	--	--	--	--	--	--	--	Sickle tail protein homolog GN=KIAA1217 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: sickle tail protein homolog isoform 1 [Ceratotherium simum simum]
ENSG00000120594(PLXDC2)	--	0.076344722	9	0.049762727	10	0.111755408	8	0.290227493	32	0.890655863	80	0.827556614	89	0.248471378	1.642461859	normal	1.61E-09	2.804022919	up	1.48E-12	3.242686354	up	0.001449141	2.877399791	up	--	--	--	--	--	[W]	Extracellular structures	Plexin repeat	Plexin domain-containing protein 2 (Precursor) GN=PLXDC2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: plexin domain-containing protein 2 [Canis lupus familiaris]
ENSG00000120616(EPC1)	--	6.235084	413	7.325246553	454	4.6652039	339	5.865103032	410	6.523773557	405	5.78610814	416	0.969173221	-0.041196317	normal	0.950095042	-0.185542146	normal	0.905117156	0.285853783	normal	0.987079908	0.00800923	normal	--	--	--	K11322|0|ptr:450393|EPC1; enhancer of polycomb homolog 1 (Drosophila); K11322 enhancer of polycomb-like protein (A)	--	[K]	Transcription	Enhancer of Polycomb C-terminus;; Enhancer of polycomb-like	Enhancer of polycomb homolog 1 GN=EPC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: enhancer of polycomb homolog 1 isoform X1 [Felis catus]
ENSG00000120647(CCDC77)	--	6.657143405	319	5.8482414	263	8.154807933	369	6.029253	299	5.448498	250	7.189485937	339	0.960758498	-0.123627997	normal	0.962364765	-0.09400675	normal	0.960624656	-0.130070637	normal	0.740304548	-0.11929587	normal	--	--	--	K16757|0|ptr:746193|CCDC77; coiled-coil domain containing 77; K16757 coiled-coil domain-containing protein 77 (A)	--	--	--	--	Coiled-coil domain-containing protein 77 GN=CCDC77 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 77 [Ceratotherium simum simum]
ENSG00000120656(TAF12)	--	7.842239	173	7.654636	171	7.946151	174	11.600497	258	10.838677	237	8.919271	197	0.484948985	0.541803437	normal	0.749919347	0.446099745	normal	0.955375256	0.169432134	normal	0.186090987	0.395870777	normal	--	--	"Cellular Component: transcription factor TFIID complex (GO:0005669);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	"K03126|9.58938e-117|hsa:6883|TAF12, TAF2J, TAFII20; TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa; K03126 transcription initiation factor TFIID subunit 12 (A)"	Basal transcription factors (ko03022)	[K]	Transcription	Transcription initiation factor TFIID subunit A;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone;; Core histone H2A/H2B/H3/H4	Transcription initiation factor TFIID subunit 12 GN=TAF12 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 12 isoform 3 [Ovis aries] 
ENSG00000120658(ENOX1)	--	1.02206829	50	0.47756039	28	0.544362662	33	0.703396814	43	0.815923065	51	0.918608056	51	0.974106598	-0.240447338	normal	0.797152047	0.810770242	normal	0.920386765	0.597554543	normal	0.589747222	0.364690082	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Protein disulfide-thiol oxidoreductase GN=ENOX1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ecto-NOX disulfide-thiol exchanger 1 [Equus caballus]
ENSG00000120662(MTRF1)	--	4.289043457	147	5.830276779	157	6.89039604	177	3.588651703	159	4.267648093	135	6.14965702	166	0.965671012	0.081558614	normal	0.94419494	-0.236769531	normal	0.9637657	-0.099975351	normal	0.870894403	-0.085271393	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: translation release factor activity (GO:0003747);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: translational termination (GO:0006415);; Molecular Function: translation release factor activity, codon specific (GO:0016149);; "	K02835|0|ptr:452558|MTRF1; mitochondrial translational release factor 1; K02835 peptide chain release factor 1 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	RF-1 domain;; PCRF domain	"Peptide chain release factor 1, mitochondrial (Precursor) GN=MTRF1 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: peptide chain release factor 1, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000120669(SOHLH2)	--	0.910848265	19	1.449529287	26	0.651778002	11	2.232108788	47	1.313473142	29	2.20151798	51	0.344428995	1.211690027	normal	0.984143253	0.129007547	normal	0.000650301	2.061638478	up	0.038040673	1.15901802	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	--	--	Helix-loop-helix DNA-binding domain	Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 GN=SOHLH2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2 [Ceratotherium simum simum]
ENSG00000120675(DNAJC15)	--	0.08386642	15	0.027624582	5	0.122499006	21	0.165887067	30	0.3233395	57	0.283241013	51	0.91688649	0.902721112	normal	5.40E-08	3.148843052	up	0.248412234	1.214048808	normal	0.00346563	1.732955338	up	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09535|4.51117e-94|hsa:29103|DNAJC15, DNAJD1, HSD18, MCJ; DnaJ (Hsp40) homolog, subfamily C, member 15; K09535 DnaJ homolog subfamily C member 15 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 15 GN=DNAJC15 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 15 [Ailuropoda melanoleuca]
ENSG00000120685(PROSER1)	--	8.678168972	634	10.82416136	778	9.305479	692	8.516070979	639	9.259805296	705	12.02074982	920	0.974152935	-0.019452218	normal	0.96204314	-0.163239955	normal	0.712318216	0.40180636	normal	0.832955286	0.08556405	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4476)	Proline and serine-rich protein 1 GN=PROSER1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: proline and serine-rich protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000120686(UFM1)	--	18.57866503	826	21.401186	948	19.239729	844	20.378039	893	19.331202	841	20.716011	860	0.975030905	0.081540243	normal	0.957869961	-0.193879208	normal	0.977624866	0.018768903	normal	0.908687153	-0.03472576	normal	--	--	--	K12162|3.51845e-39|umr:103664382|UFM1; ubiquitin-fold modifier 1; K12162 ubiquitin-fold modifier 1 (A)	--	[S]	Function unknown	Ubiquitin fold modifier 1 protein	Ubiquitin-fold modifier 1 (Precursor) GN=UFM1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"Ubiquitin-fold modifier 1, partial [Bos mutus]"
ENSG00000120688(WBP4)	--	3.94354	212	4.32011	233	4.34998	231	4.3054	233	3.90826	209	4.7377	254	0.962499597	0.104709429	normal	0.95134744	-0.177039581	normal	0.959988157	0.12784577	normal	0.972572149	0.021129991	normal	[A]	RNA processing and modification	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	"K13220|0|hsa:11193|WBP4, FBP21; WW domain binding protein 4; K13220 WW domain-binding protein 4 (A)"	--	[A]	RNA processing and modification	WW domain;; U1 zinc finger	WW domain-binding protein 4 GN=WBP4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: WW domain-binding protein 4 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000120690(ELF1)	--	12.24033591	722	9.900972155	666	10.11393255	624	15.54670054	983	19.01015733	1242	17.73353373	1158	0.675250385	0.413603436	normal	7.55E-05	0.876165204	normal	4.99E-05	0.882131965	normal	2.07E-06	0.728868817	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09428|0|ggo:101153562|ELF1; ETS-related transcription factor Elf-1; K09428 E74-like factor 1/2/4 (A)	--	[K]	Transcription	Transcription factor protein N terminal;; Ets-domain	ETS-related transcription factor Elf-1 GN=ELF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS-related transcription factor Elf-1 [Oryctolagus cuniculus] 
ENSG00000120693(SMAD9)	--	0.10409144	9	0.174272474	15	0.09236281	7	0.04624422	4	0.1117131	9	0.05719751	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K16791|0|hsa:4093|SMAD9, MADH6, MADH9, PPH2, SMAD8, SMAD8A, SMAD8B; SMAD family member 9; K16791 mothers against decapentaplegic homolog 9 (A)"	TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain;; Interferon-regulatory factor 3	Mothers against decapentaplegic homolog 9 GN=SMAD9 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mothers against decapentaplegic homolog 9 isoform 1 [Ceratotherium simum simum]
ENSG00000120694(HSPH1)	--	50.86529775	3870	57.57172228	4339	70.81514535	5301	78.77835394	5945	62.51576712	4711	56.77772524	4312	0.102087941	0.588321226	normal	0.991113831	0.097211666	normal	0.953983924	-0.306101799	normal	0.725437382	0.126080827	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	K09485|0|ptr:452522|HSPH1; heat shock 105kDa/110kDa protein 1; K09485 heat shock protein 110kDa (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein	Heat shock protein 105 kDa GN=HSPH1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein 105 kDa isoform X3 [Oryctolagus cuniculus]
ENSG00000120696(KBTBD7)	--	3.00042	219	3.17692	233	3.14903	228	2.47998	182	2.47347	180	2.78628	203	0.915019099	-0.295546288	normal	0.832387655	-0.390864513	normal	0.953286135	-0.174617337	normal	0.374520851	-0.288157982	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10474|0|ptr:467268|KBTBD7; kelch repeat and BTB (POZ) domain containing 7; K10474 kelch repeat and BTB domain-containing protein 6/7 (A)	--	--	--	"BTB/POZ domain;; BTB And C-terminal Kelch;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif"	Kelch repeat and BTB domain-containing protein 7 GN=KBTBD7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: kelch repeat and BTB domain-containing protein 7 [Galeopterus variegatus]
ENSG00000120697(ALG5)	--	14.158805	249	14.97850155	267	13.992861	247	16.637094	298	19.787119	346	19.874146	350	0.937944182	0.227052383	normal	0.85001917	0.350756278	normal	0.538317645	0.492009555	normal	0.156880061	0.360798468	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K00729|0|ptr:452541|ALG5; ALG5, dolichyl-phosphate beta-glucosyltransferase; K00729 dolichyl-phosphate beta-glucosyltransferase [EC:2.4.1.117] (A)"	N-Glycan biosynthesis (ko00510)	[R]	General function prediction only	Glycosyl transferase family 2;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2	Dolichyl-phosphate beta-glucosyltransferase GN=ALG5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: dolichyl-phosphate beta-glucosyltransferase isoformX4 [Canis lupus familiaris]
ENSG00000120699(EXOSC8)	--	17.779	332	19.183921	362	18.989737	359	17.675569	335	17.167	319	15.976631	297	0.968249315	-0.017772532	normal	0.944043806	-0.202955904	normal	0.910559638	-0.280511163	normal	0.579087196	-0.168491127	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K12586|0|hsa:11340|EXOSC8, CIP3, EAP2, OIP2, PCH1C, RRP43, Rrp43p, bA421P11.3, p9; exosome component 8 (EC:3.1.13.-); K12586 exosome complex component RRP43 (A)"	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	"3' exoribonuclease family, domain 1;; 3' exoribonuclease family, domain 2"	Exosome complex component RRP43 GN=EXOSC8 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component RRP43 isoform X2 [Mustela putorius furo] 
ENSG00000120705(ETF1)	--	66.52457273	4170	68.35822448	4182	68.80538289	4157	71.84787073	4694	71.1231399	4574	64.60494351	4195	0.98917542	0.139889597	normal	0.990480964	0.107799464	normal	0.992405353	0.00483487	normal	0.721622195	0.084514707	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K03265|0|acs:100566787|etf1; eukaryotic translation termination factor 1; K03265 peptide chain release factor subunit 1 (A)	mRNA surveillance pathway (ko03015)	[J]	"Translation, ribosomal structure and biogenesis"	eRF1 domain 2;; eRF1 domain 3;; eRF1 domain 1	Eukaryotic peptide chain release factor subunit 1 GN=ETF1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic peptide chain release factor subunit 1 [Myotis lucifugus]
ENSG00000120708(TGFBI)	--	484.425712	27423	431.2545542	23959	445.3777699	24873	965.2155858	52292	1113.308006	61777	666.6099979	37597	2.98E-05	0.900334455	normal	1.34E-13	1.345020756	up	0.300219114	0.587716315	normal	0.002750129	0.970057677	normal	[M]	Cell wall/membrane/envelope biogenesis	--	--	--	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Fasciclin domain	Transforming growth factor-beta-induced protein ig-h3 (Precursor) GN=TGFBI OS=Homo sapiens (Human) PE=1 SV=1	MW	Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: transforming growth factor-beta-induced protein ig-h3 [Camelus bactrianus]
ENSG00000120709(FAM53C)	--	16.216121	1269	16.45330135	1299	13.88895814	1139	14.75477413	1167	14.124746	1114	14.5482789	1175	0.972195751	-0.151528377	normal	0.946823581	-0.242773201	normal	0.980807014	0.036553782	normal	0.577010037	-0.122551956	normal	--	--	--	--	--	--	--	Family of FAM53	Protein FAM53C GN=FAM53C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM53C isoform X1 [Oryctolagus cuniculus] 
ENSG00000120725(SIL1)	--	66.62290647	752	18.24675309	679	27.34710049	725	39.82815775	825	49.96654865	843	30.7869124	754	0.972147697	0.102628965	normal	0.905834383	0.290113635	normal	0.975156865	0.048193507	normal	0.525184117	0.146466342	normal	--	--	--	"K14001|0|hsa:64374|SIL1, BAP, MSS, ULG5; SIL1 nucleotide exchange factor; K14001 nucleotide exchange factor SIL1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Nucleotide exchange factor SIL1 (Precursor) GN=SIL1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: nucleotide exchange factor SIL1 isoform X1 [Equus caballus] 
ENSG00000120727(PAIP2)	--	51.91957901	1231	49.101716	1169	59.71423986	1397	60.53677511	1454	52.334587	1235	60.02046111	1421	0.961324804	0.209123877	normal	0.980058521	0.057736883	normal	0.983340016	0.016265633	normal	0.688881804	0.093235515	normal	--	--	--	--	--	--	--	Ataxin-2 C-terminal region	Polyadenylate-binding protein-interacting protein 2 GN=PAIP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: polyadenylate-binding protein-interacting protein 2 isoform 1 [Canis lupus familiaris]
ENSG00000120729(MYOT)	--	0	0	0	0	0.032547171	0	0.064989431	2	0.065059385	2	0.032304913	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	Myotilin GN=MYOT OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: myotilin isoform X1 [Equus przewalskii]
ENSG00000120733(KDM3B)	--	21.964842	2947	23.00936	3149	20.98751184	2915	20.00615485	2729	21.6489412	2861	23.721281	3255	0.98476735	-0.141630168	normal	0.983466297	-0.159720306	normal	0.984841487	0.150796151	normal	0.855593371	-0.047580084	normal	--	--	--	"K15601|0|hsa:51780|KDM3B, 5qNCA, C5orf7, JMJD1B, NET22; lysine (K)-specific demethylase 3B; K15601 lysine-specific demethylase 3 [EC:1.14.11.-] (A)"	--	[K]	Transcription	"JmjC domain, hydroxylase"	Lysine-specific demethylase 3B GN=KDM3B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: lysine-specific demethylase 3B [Oryctolagus cuniculus]
ENSG00000120738(EGR1)	--	0.561961215	30	0.491727	27	0.457719259	24	0.075374362	4	0.452283442	24	0.110359026	6	0.005641212	-2.535789966	down	0.984327313	-0.180614839	normal	0.428948294	-1.77107928	normal	0.063779812	-1.272473717	normal	[R]	General function prediction only	--	K09203|0|mcc:716786|EGR1; early growth response 1; K09203 early growth response protein 1 (A)	Prion diseases (ko05020);; HTLV-I infection (ko05166)	[R]	General function prediction only	"Domain of unknown function (DUF3432);; Domain of unknown function (DUF3446);; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Early growth response protein 1 GN=EGR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: early growth response protein 1 [Tupaia chinensis]
ENSG00000120742(SERP1)	--	45.46651946	1620	45.24662342	1786	48.78081	1752	66.593238	2547	61.47616444	2374	69.459691	2607	0.036225994	0.621499161	normal	0.803054106	0.388874835	normal	0.124636755	0.564694226	normal	0.000265897	0.524333822	normal	--	--	--	--	--	[S]	Function unknown	Ribosome associated membrane protein RAMP4	Stress-associated endoplasmic reticulum protein 1 GN=SERP1 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	hypothetical protein PANDA_012639 [Ailuropoda melanoleuca]
ENSG00000120756(PLS1)	--	15.20206052	804	13.53470441	766	13.0360669	752	22.84937503	1209	19.15473745	1046	19.07569965	927	0.144505192	0.556841433	normal	0.644261248	0.427315431	normal	0.904351529	0.293013594	normal	0.007418141	0.432492367	normal	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	K17275|0|ptr:460746|PLS1; plastin 1; K17275 plastin-1 (A)	--	[Z]	Cytoskeleton	Calponin homology (CH) domain;; EF-hand domain pair;; EF hand;; EF-hand domain pair;; EF hand;; EF-hand domain;; CAMSAP CH domain	Plastin-1 GN=PLS1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: plastin-1 isoform X2 [Tupaia chinensis] 
ENSG00000120784(ZFP30)	--	3.012408	230	3.3662172	284	3.88640138	215	5.631788023	356	5.671597464	403	4.493270858	375	0.211466666	0.596187216	normal	0.549203786	0.481300926	normal	0.00803703	0.790002208	normal	0.004813284	0.616092384	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:22835|ZFP30, ZNF745; ZFP30 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; NTF2 fold immunity protein;; TFIIH C1-like domain;; Transposase zinc-ribbon domain"	Zinc finger protein 30 homolog GN=ZFP30 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 30 homolog [Galeopterus variegatus]
ENSG00000120798(NR2C1)	--	16.55923269	566	19.80483722	581	19.78525812	579	12.59211328	519	15.21018668	556	16.19704434	576	0.959874164	-0.155458882	normal	0.969180862	-0.084654565	normal	0.973237749	-0.015744748	normal	0.770554066	-0.084941155	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08543|0|mcf:102136205|NR2C1; nuclear receptor subfamily 2, group C, member 1; K08543 testicular receptor 2 (A)"	--	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor subfamily 2 group C member 1 GN=NR2C1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor subfamily 2 group C member 1 [Leptonychotes weddellii]
ENSG00000120800(UTP20)	--	8.83371	1586	11.1037	1970	11.0988	1949	9.30146	1671	9.83416	1760	10.6401	1908	0.984300844	0.044444752	normal	0.973327801	-0.183897306	normal	0.986148957	-0.038933828	normal	0.790565258	-0.064836127	normal	--	--	--	"K14772|0|hsa:27340|UTP20, DRIM; UTP20, small subunit (SSU) processome component, homolog (yeast); K14772 U3 small nucleolar RNA-associated protein 20 (A)"	--	[V]	Defense mechanisms	Down-regulated in metastasis	Small subunit processome component 20 homolog GN=UTP20 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: small subunit processome component 20 homolog [Ceratotherium simum simum]
ENSG00000120802(TMPO)	--	63.98051313	4039	64.10471682	3937	65.411252	4027	78.10375969	4949	74.24846655	4633	61.0140369	3803	0.970752238	0.2622164	normal	0.981030718	0.2133478	normal	0.990547773	-0.090823872	normal	0.517734466	0.135303975	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	Lamina-associated polypeptide 2 alpha;; Thymopoietin protein;; LEM domain	Thymopentin GN=TMPO OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	"PREDICTED: lamina-associated polypeptide 2, isoforms beta/delta/epsilon/gamma isoform X1 [Mustela putorius furo] "
ENSG00000120805(ARL1)	--	30.27126411	1057	33.94068496	1140	30.63954598	1020	42.0711292	1466	36.45315209	1356	39.80858632	1387	0.585772482	0.440531629	normal	0.953376889	0.228618437	normal	0.608583559	0.434552596	normal	0.021960234	0.366232686	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07942|6.79069e-113|ptr:452171|ARL1; ADP-ribosylation factor-like 1; K07942 ADP-ribosylation factor-like protein 1 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Gtr1/RagA G protein conserved region;; Signal recognition particle receptor beta subunit;; Miro-like protein;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	ADP-ribosylation factor-like protein 1 GN=ARL1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 1 [Myotis lucifugus]
ENSG00000120820(GLT8D2)	--	0.161104037	7	0.519629801	13	0.23501797	5	0.227092953	8	0.140362455	3	0.25595702	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	--	--	--	--	Glycosyl transferase family 8	Glycosyltransferase 8 domain-containing protein 2 GN=GLT8D2 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: glycosyltransferase 8 domain-containing protein 2 [Felis catus] 
ENSG00000120832(MTERF2)	--	6.629695543	223	5.863671023	211	6.5044312	231	6.184055401	197	6.373241211	225	4.549060056	191	0.946279774	-0.208153213	normal	0.963853224	0.070764256	normal	0.920880605	-0.280588338	normal	0.724807845	-0.138541654	normal	--	--	"Molecular Function: double-stranded DNA binding (GO:0003690);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15031|0|hsa:80298|MTERF2, MTERFD3, mTERFL; mitochondrial transcription termination factor 2; K15031 transcription termination factor, mitochondrial (A)"	--	[KR]	Transcription;; General function prediction only	mTERF	"Transcription termination factor 2, mitochondrial (Precursor) GN=MTERF2 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: mTERF domain-containing protein 3, mitochondrial [Galeopterus variegatus] "
ENSG00000120833(SOCS2)	--	11.04991019	318	11.21669862	344	13.46925234	329	7.926350106	241	10.22506602	269	9.97976962	301	0.7266244	-0.428439368	normal	0.818325691	-0.374362665	normal	0.959239742	-0.135961913	normal	0.234630632	-0.309720738	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	"K04695|7.71367e-146|hsa:8835|SOCS2, CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2; suppressor of cytokine signaling 2; K04695 suppressor of cytokine signaling 2 (A)"	Jak-STAT signaling pathway (ko04630);; Insulin signaling pathway (ko04910);; Prolactin signaling pathway (ko04917);; Type II diabetes mellitus (ko04930)	[T]	Signal transduction mechanisms	SOCS box;; SH2 domain	Suppressor of cytokine signaling 2 GN=SOCS2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: suppressor of cytokine signaling 2 [Equus przewalskii] 
ENSG00000120837(NFYB)	--	17.40277541	682	20.19621301	813	18.48158607	727	17.73647144	659	14.0181205	559	17.5092593	681	0.972073087	-0.080141849	normal	0.172377706	-0.560568224	normal	0.970849846	-0.102371936	normal	0.221588265	-0.247871211	normal	[B]	Chromatin structure and dynamics	--	"K08065|4.38647e-152|pps:100979136|NFYB; nuclear transcription factor Y, beta; K08065 nuclear transcription Y subunit beta (A)"	Antigen processing and presentation (ko04612);; Tuberculosis (ko05152);; HTLV-I infection (ko05166)	[K]	Transcription	Histone-like transcription factor (CBF/NF-Y) and archaeal histone;; Core histone H2A/H2B/H3/H4	Nuclear transcription factor Y subunit beta GN=NFYB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	nuclear transcription factor Y subunit beta [Sus scrofa] 
ENSG00000120860(WASHC3)	--	17.89688124	260	16.34457761	240	19.342701	284	21.40696921	321	19.42581135	283	20.66578042	307	0.917540886	0.271781888	normal	0.941067181	0.215091836	normal	0.962978156	0.103525953	normal	0.530857893	0.195470057	normal	--	--	Cellular Component: WASH complex (GO:0071203);; 	K18463|5.30783e-125|ptr:740826|CCDC53; coiled-coil domain containing 53; K18463 WASH complex subunit CCDC53 (A)	--	[S]	Function unknown	Predicted coiled-coil domain-containing protein (DUF2360)	WASH complex subunit CCDC53 GN=CCDC53 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: WASH complex subunit CCDC53 isoform X1 [Tupaia chinensis]
ENSG00000120868(APAF1)	--	4.495504218	498	4.992910817	601	5.440278148	617	8.865893476	996	6.978499183	805	9.335472317	1024	5.32E-06	0.96701846	normal	0.729029815	0.399326268	normal	0.004777757	0.721195423	normal	4.95E-05	0.698172654	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; Molecular Function: ADP binding (GO:0043531);; 	K02084|0|pon:100459074|APAF1; apoptotic peptidase activating factor 1; K02084 apoptotic protease-activating factor (A)	p53 signaling pathway (ko04115);; Apoptosis (ko04210);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Legionellosis (ko05134);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Small cell lung cancer (ko05222)	[R]	General function prediction only	"WD domain, G-beta repeat;; NB-ARC domain;; Caspase recruitment domain;; Eukaryotic translation initiation factor eIF2A"	Apoptotic protease-activating factor 1 GN=APAF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: apoptotic protease-activating factor 1 isoform X1 [Camelus ferus]
ENSG00000120875(DUSP4)	--	92.35086597	9248	93.99061812	9614	93.06375993	9463	91.27384567	9195	86.15121075	8603	104.0580796	10451	0.995885233	-0.039117569	normal	0.991749909	-0.181693291	normal	0.994453885	0.13495949	normal	0.939370018	-0.024719759	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K04459|0|hsa:1846|DUSP4, HVH2, MKP-2, MKP2, TYP; dual specificity phosphatase 4 (EC:3.1.3.16 3.1.3.48); K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 4 GN=DUSP4 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 4 [Ceratotherium simum simum]
ENSG00000120885(CLU)	--	472.0334161	8381	660.0369928	12622	426.6250515	9157	336.9765324	6523	373.9435544	7275	299.7556401	5779	0.890426851	-0.392337252	normal	0.000328598	-0.816217399	normal	0.015818542	-0.672205584	normal	0.039852912	-0.645251799	normal	--	--	--	"K17252|0|hsa:1191|CLU, APO-J, APOJ, CLI, CLU1, CLU2, KUB1, NA1/NA2, SGP-2, SGP2, SP-40, TRPM-2, TRPM2; clusterin; K17252 clusterin (A)"	--	--	--	Clusterin	Clusterin alpha chain (Precursor) GN=CLU OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: clusterin isoform X1 [Tupaia chinensis]
ENSG00000120889(TNFRSF10B)	--	63.4902	4330	76.577	5215	75.1447	5073	82.2389	5571	79.2002	5252	98.5806	6634	0.937140929	0.332632743	normal	0.993424608	-0.011223651	normal	0.89454618	0.378649419	normal	0.241675918	0.235432743	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K04722|0|hsa:8795|TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9; tumor necrosis factor receptor superfamily, member 10b; K04722 tumor necrosis factor receptor superfamily member 10 (A)"	Cytokine-cytokine receptor interaction (ko04060);; p53 signaling pathway (ko04115);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; Measles (ko05162);; Influenza A (ko05164)	--	--	Death domain;; TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 10B (Precursor) GN=UNQ160/PRO186 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 10B [Physeter catodon]
ENSG00000120896(SORBS3)	--	40.95054499	1575	41.28343801	1476	41.99576035	1654	43.64042909	1715	41.71947727	1674	38.28201073	1599	0.982334451	0.091938523	normal	0.9745689	0.160026215	normal	0.983932589	-0.057027704	normal	0.800513651	0.063033959	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Sorbin homologous domain	Vinexin GN=SORBS3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: vinexin [Galeopterus variegatus]
ENSG00000120899(PTK2B)	--	11.77028762	859	15.78655263	898	11.03437947	759	8.812483007	643	9.162576942	606	10.1729741	723	0.555408906	-0.447742328	normal	0.105421253	-0.587611277	normal	0.973528539	-0.078235945	normal	0.035172235	-0.372608139	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein tyrosine kinase activity (GO:0004713);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: focal adhesion (GO:0005925);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal complex assembly (GO:0007172);; 	"K05871|0|hsa:2185|PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK; protein tyrosine kinase 2 beta (EC:2.7.10.2); K05871 focal adhesion kinase 2 [EC:2.7.10.2] (A)"	Calcium signaling pathway (ko04020);; Chemokine signaling pathway (ko04062);; Natural killer cell mediated cytotoxicity (ko04650);; Leukocyte transendothelial migration (ko04670);; GnRH signaling pathway (ko04912);; Hepatitis B (ko05161)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Focal adhesion targeting region;; Protein kinase domain;; FERM central domain	Protein-tyrosine kinase 2-beta GN=PTK2B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein-tyrosine kinase 2-beta isoform X1 [Tupaia chinensis] 
ENSG00000120910(PPP3CC)	--	5.61183623	213	4.254954709	171	5.910606088	215	6.0224789	234	5.123862144	200	4.935099304	187	0.962547968	0.104106238	normal	0.947674847	0.20291644	normal	0.946901262	-0.208019566	normal	0.958460685	0.030383825	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K04348|0|hsa:5533|PPP3CC, CALNA3, CNA3, PP2Bgamma; protein phosphatase 3, catalytic subunit, gamma isozyme (EC:3.1.3.16); K04348 serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Oocyte meiosis (ko04114);; Apoptosis (ko04210);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Oxytocin signaling pathway (ko04921);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; HTLV-I infection (ko05166)	[R]	General function prediction only	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform GN=PPP3CC OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform [Oryctolagus cuniculus]
ENSG00000120913(PDLIM2)	--	81.05555997	1041	65.44871686	907	76.15511384	994	75.33536698	969	68.96689123	825	66.71528871	861	0.971857419	-0.13402866	normal	0.965472046	-0.157858882	normal	0.952138252	-0.215171988	normal	0.417072694	-0.169628329	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	PDZ domain (Also known as DHR or GLGF);; LIM domain	PDZ and LIM domain protein 2 GN=PDLIM2 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: PDZ and LIM domain protein 2 [Ceratotherium simum simum]
ENSG00000120915(EPHX2)	--	7.40221417	269	9.7729744	270	13.54598331	315	7.875990493	184	6.232305704	192	7.447051001	183	0.357516185	-0.574737324	normal	0.562141823	-0.509875474	normal	0.014118835	-0.786782265	normal	0.009822856	-0.632280715	normal	[R]	General function prediction only	--	"K08726|0|ptr:464074|EPHX2; epoxide hydrolase 2, cytoplasmic; K08726 soluble epoxide hydrolase / lipid-phosphate phosphatase [EC:3.3.2.10 3.1.3.76] (A)"	Arachidonic acid metabolism (ko00590);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Haloacid dehalogenase-like hydrolase;; Alpha/beta hydrolase family;; HAD-hyrolase-like	Lipid-phosphate phosphatase GN=EPHX2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: bifunctional epoxide hydrolase 2 [Tupaia chinensis]
ENSG00000120925(RNF170)	--	10.4710777	511	8.917285	454	9.6077235	423	10.84245893	506	10.40292908	512	12.303004	566	0.971009731	-0.044882554	normal	0.958733816	0.151549385	normal	0.704927365	0.410579689	normal	0.509389078	0.169500482	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K15707|2.73959e-161|hsa:81790|RNF170, ADSA, SNAX1; ring finger protein 170; K15707 RING finger protein 170 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Protein of unknown function (DUF1232);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc finger of C3HC4-type, RING;; Ring finger domain"	E3 ubiquitin-protein ligase RNF170 GN=RNF170 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF170 isoform X1 [Tupaia chinensis]
ENSG00000120937(NPPB)	--	0	0	0.106034	1	0	0	0.311052	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	"K12335|3.16192e-79|hsa:4879|NPPB, BNP; natriuretic peptide B; K12335 natriuretic peptide B (A)"	cGMP-PKG signaling pathway (ko04022)	--	--	Atrial natriuretic peptide	BNP(5-29) (Precursor) GN=NPPB OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: natriuretic peptides B [Vicugna pacos]
ENSG00000120942(UBIAD1)	--	7.052747087	451	5.82760886	371	7.490770649	466	7.254642938	434	7.081936482	453	7.394195694	431	0.96712861	-0.085966075	normal	0.9174051	0.265683861	normal	0.963697967	-0.1205267	normal	0.981741102	0.01230396	normal	[H]	Coenzyme transport and metabolism	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765);; "	--	--	[S]	Function unknown	UbiA prenyltransferase family	UbiA prenyltransferase domain-containing protein 1 GN=UBIAD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ubiA prenyltransferase domain-containing protein 1 [Equus caballus] 
ENSG00000120948(TARDBP)	--	81.15167775	3061	94.1947825	3404	99.25208803	3561	103.306148	3919	93.51103317	3286	85.24079704	3026	0.927948209	0.325505567	normal	0.98972707	-0.072292423	normal	0.970038911	-0.243049786	normal	0.983948554	0.007343283	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	TAR DNA-binding protein 43 GN=TARDBP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TAR DNA-binding protein 43 [Condylura cristata]
ENSG00000120949(TNFRSF8)	--	0	0	0	0	0	0	0	0	0	0	0.052456638	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05145|0|hsa:943|TNFRSF8, CD30, D1S166E, Ki-1; tumor necrosis factor receptor superfamily, member 8; K05145 tumor necrosis factor receptor superfamily member 8 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 8 (Precursor) GN=TNFRSF8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 8 [Ceratotherium simum simum]
ENSG00000120963(ZNF706)	--	49.1211729	783	50.72457033	835	52.0558652	807	68.18239966	1102	52.26161505	853	55.41655864	1001	0.495591868	0.461441275	normal	0.977031565	0.009326275	normal	0.897608919	0.302000881	normal	0.152656757	0.264045499	normal	--	--	--	--	--	[S]	Function unknown	4F5 protein family;; Zinc-binding;; Zinc-finger of C2H2 type	Zinc finger protein 706 GN=ZNF706 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 706-like [Echinops telfairi]
ENSG00000120992(LYPLA1)	--	54.93388943	1767	48.76614283	1574	54.89601935	1741	61.75311833	1959	52.3286767	1674	54.68336228	1770	0.981919611	0.117885719	normal	0.983114111	0.067374655	normal	0.985590887	0.015528338	normal	0.785891898	0.066904788	normal	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	K06128|7.9576e-170|pon:100172358|LYPLA1; lysophospholipase I (EC:3.1.2.-); K06128 lysophospholipase I [EC:3.1.1.5] (A)	Glycerophospholipid metabolism (ko00564);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Phospholipase/Carboxylesterase;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold	Acyl-protein thioesterase 1 GN=LYPLA1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-protein thioesterase 1 [Oryctolagus cuniculus]
ENSG00000121005(CRISPLD1)	--	6.935311656	465	6.591884993	415	8.705990619	504	1.294480096	87	2.392150921	84	1.01264751	65	0	-2.428159968	down	0	-2.305353587	down	0	-2.934238127	down	4.31E-34	-2.573702826	down	[S]	Function unknown	--	--	--	[S]	Function unknown	LCCL domain;; Cysteine-rich secretory protein family	Cysteine-rich secretory protein LCCL domain-containing 1 (Precursor) GN=CRISPLD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cysteine-rich secretory protein LCCL domain-containing 1 isoform X1 [Ailuropoda melanoleuca]
ENSG00000121022(COPS5)	--	38.7507148	904	37.1329	876	39.441177	921	45.674242	1077	41.904727	974	43.16934	1011	0.950915821	0.221446161	normal	0.970603773	0.13134923	normal	0.972414685	0.12602093	normal	0.450419697	0.159632489	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K09613|0|umr:103677490|COPS5; COP9 signalosome subunit 5; K09613 COP9 signalosome complex subunit 5 [EC:3.4.-.-] (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Prokaryotic homologs of the JAB domain	COP9 signalosome complex subunit 5 GN=COPS5 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	COP9 signalosome complex subunit 5 [Tupaia chinensis]
ENSG00000121039(RDH10)	--	9.79908	503	14.71760191	856	10.54585021	591	9.421082242	534	11.229791	635	21.6718	1246	0.970728637	0.055285177	normal	0.559674317	-0.451351189	normal	1.03E-07	1.065861211	up	0.76701979	0.289549524	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K11151|0|tup:102492322|RDH10; retinol dehydrogenase 10 (all-trans); K11151 retinol dehydrogenase 10 [EC:1.1.1.-] (A)	Retinol metabolism (ko00830)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain	Retinol dehydrogenase 10 GN=RDH10 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	"Retinol dehydrogenase 10, partial [Bos mutus]"
ENSG00000121053(EPX)	--	0	0	0.0196641	1	0	0	0.0396623	2	0.0192482	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10788|0|hsa:8288|EPX, EPO, EPP, EPX-PEN; eosinophil peroxidase (EC:1.11.1.7); K10788 eosinophil peroxidase [EC:1.11.1.7] (A)"	Asthma (ko05310)	[R]	General function prediction only	Animal haem peroxidase	Eosinophil peroxidase heavy chain (Precursor) GN=EPX OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: eosinophil peroxidase [Loxodonta africana]
ENSG00000121057(AKAP1)	--	23.70878263	1934	23.82281788	1841	24.10264184	1915	25.96660147	2133	27.18668811	2179	25.40268383	2034	0.983516088	0.11038039	normal	0.966110653	0.221582545	normal	0.985067504	0.078623592	normal	0.507391763	0.136150002	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K16518|0|hsa:8165|AKAP1, AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, TDRD17; A kinase (PRKA) anchor protein 1; K16518 A-kinase anchor protein 1, mitochondrial (A)"	--	--	--	Tudor domain;; KH domain;; KH domain;; RII binding domain	"A-kinase anchor protein 1, mitochondrial (Precursor) GN=AKAP1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: A-kinase anchor protein 1, mitochondrial [Galeopterus variegatus] "
ENSG00000121058(COIL)	--	12.90170267	611	14.87030227	705	12.81880251	600	13.20830237	631	13.01560228	615	11.56870239	549	0.973931284	0.015596769	normal	0.944851052	-0.21796235	normal	0.964078557	-0.136089074	normal	0.659045708	-0.115889698	normal	--	--	--	"K13150|0|hsa:8161|COIL, CLN80, p80-coilin; coilin; K13150 coilin (A)"	--	--	--	--	Coilin GN=COIL OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coilin [Ceratotherium simum simum]
ENSG00000121060(TRIM25)	--	24.48357988	2717	26.14043	2918	24.87977584	2761	33.448147	3711	29.49012	3254	35.60537483	3956	0.747707195	0.418757843	normal	0.985861487	0.135741169	normal	0.350141461	0.51032536	normal	0.022470963	0.35822153	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K10652|0|hsa:7706|TRIM25, EFP, RNF147, Z147, ZNF147; tripartite motif containing 25 (EC:6.3.2.19 6.3.2.n3); K10652 tripartite motif-containing protein 25 [EC:6.3.2.19] (A)"	NF-kappa B signaling pathway (ko04064);; RIG-I-like receptor signaling pathway (ko04622);; Influenza A (ko05164)	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin/ISG15 ligase TRIM25 GN=TRIM25 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: E3 ubiquitin/ISG15 ligase TRIM25, partial [Galeopterus variegatus]"
ENSG00000121064(SCPEP1)	--	31.70004237	1061	32.73279276	1109	27.38151374	911	26.7714422	893	27.6739735	908	30.416286	981	0.919206099	-0.279083645	normal	0.894879936	-0.309454477	normal	0.975026616	0.098353274	normal	0.414868837	-0.168499447	normal	[E]	Amino acid transport and metabolism	Molecular Function: serine-type carboxypeptidase activity (GO:0004185);; Biological Process: proteolysis (GO:0006508);; 	"K09646|0|hsa:59342|SCPEP1, HSCP1, RISC; serine carboxypeptidase 1; K09646 serine carboxypeptidase 1 [EC:3.4.16.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Serine carboxypeptidase	Retinoid-inducible serine carboxypeptidase (Precursor) GN=SCPEP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: retinoid-inducible serine carboxypeptidase [Canis lupus familiaris]
ENSG00000121067(SPOP)	--	16.64992725	679	17.00175312	754	18.27469879	759	22.36634929	953	21.91471945	850	21.89164753	994	0.515910777	0.457355191	normal	0.965468524	0.151186041	normal	0.7702946	0.380190664	normal	0.062240083	0.33059888	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10523|0|umr:103660517|SPOP; speckle-type POZ protein; K10523 speckle-type POZ protein (A)	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	BTB/POZ domain;; MATH domain	Speckle-type POZ protein GN=SPOP OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	"Speckle-type POZ protein, partial [Bos mutus]"
ENSG00000121068(TBX2)	--	2.067846376	121	1.985763	114	2.039880749	120	2.325750529	139	2.184679327	130	1.89715834	114	0.960045922	0.167262927	normal	0.959471969	0.165988163	normal	0.967721899	-0.081241454	normal	0.881323279	0.087806209	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10176|0|hsa:6909|TBX2; T-box 2; K10176 T-box protein 2 (A)	--	[K]	Transcription	T-box;; T-box transcription factor	T-box transcription factor TBX2 GN=TBX2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	RecName: Full=T-box transcription factor TBX2; Short=T-box protein 2 [Canis lupus familiaris]
ENSG00000121073(SLC35B1)	--	47.83507552	1098	46.3633263	1014	45.61592804	975	53.8542342	1244	51.107093	1156	67.33816103	1337	0.971941981	0.149080101	normal	0.96729892	0.167423205	normal	0.559216655	0.446639942	normal	0.15324447	0.25454115	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K15275|0|ptr:747427|SLC35B1; solute carrier family 35, member B1; K15275 solute carrier family 35 (UDP-galactose transporter), member B1 (A)"	--	[G]	Carbohydrate transport and metabolism	UAA transporter family;; EamA-like transporter family;; Triose-phosphate Transporter family;; Multidrug resistance efflux transporter	Solute carrier family 35 member B1 GN=SLC35B1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 35 member B1 isoform 2 [Dasypus novemcinctus]
ENSG00000121075(TBX4)	--	0.090233522	6	0.020333097	1	0.079614307	3	0.016359372	1	0.135229262	7	0.26936338	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10178|0|pps:100970064|TBX4; T-box 4; K10178 T-box protein 4 (A)	--	[K]	Transcription	T-box	T-box transcription factor TBX4 GN=TBX4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: T-box transcription factor TBX4 isoform X1 [Oryctolagus cuniculus] 
ENSG00000121101(TEX14)	--	0.04536933	5	0.018189875	2	0.071998679	7	0.009101075	1	0.00882571	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17540|0|hsa:56155|TEX14, CT113; testis expressed 14; K17540 inactive serine/threonine-protein kinase TEX14 (A)"	--	--	--	Protein tyrosine kinase;; Protein kinase domain;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies)	Inactive serine/threonine-protein kinase TEX14 GN=TEX14 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: inactive serine/threonine-protein kinase TEX14 isoform 1 [Ceratotherium simum simum]
ENSG00000121104(FAM117A)	--	2.062876377	93	2.784465997	104	2.030032968	93	1.50101739	64	1.528227462	69	1.5426949	55	0.823397465	-0.558793291	normal	0.727700433	-0.602507665	normal	0.524527465	-0.750051476	normal	0.127138788	-0.64699393	normal	--	--	--	--	--	--	--	Protein Family FAM117	Protein FAM117A GN=FAM117A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	protein FAM117A [Bos taurus] 
ENSG00000121152(NCAPH)	--	20.79078155	1147	21.07640905	1135	23.72758231	1256	12.4088504	711	13.63591904	716	10.27127445	595	0.00423215	-0.719539297	normal	0.01232739	-0.684927559	normal	4.98E-08	-1.084224681	down	1.46E-08	-0.828638399	normal	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Cellular Component: condensin complex (GO:0000796);; Biological Process: mitotic chromosome condensation (GO:0007076);; 	"K06676|0|ptr:470438|NCAPH, BRRN1; non-SMC condensin I complex, subunit H; K06676 condensin complex subunit 2 (A)"	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Condensin complex subunit 2	Condensin complex subunit 2 GN=NCAPH OS=Homo sapiens (Human) PE=1 SV=3	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: condensin complex subunit 2 [Galeopterus variegatus]
ENSG00000121207(LRAT)	--	0.272169954	12	0.179653379	14	0.013272533	0	0.22331176	4	0.256844393	4	0.06595211	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K00678|4.69247e-159|pps:100990532|LRAT; lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase); K00678 phosphatidylcholine-retinol O-acyltransferase [EC:2.3.1.135] (A)	Retinol metabolism (ko00830);; Vitamin digestion and absorption (ko04977)	--	--	Lecithin retinol acyltransferase	Lecithin retinol acyltransferase GN=LRAT OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: lecithin retinol acyltransferase isoform X1 [Tupaia chinensis] 
ENSG00000121210(KIAA0922)	--	2.384860523	243	2.0416017	204	2.324712679	233	2.920822959	299	2.873080419	290	2.10484565	218	0.921406929	0.266833826	normal	0.621548809	0.483039889	normal	0.962616862	-0.103597964	normal	0.481035256	0.225098439	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF3651)	Transmembrane protein 131-like (Precursor) GN=KIAA0922 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 131-like [Leptonychotes weddellii]
ENSG00000121211(MND1)	--	10.19841103	155	10.15998592	161	12.93599482	206	9.160769	141	7.095455169	113	8.610747689	139	0.958434739	-0.165682489	normal	0.695587755	-0.52623177	normal	0.488929057	-0.570717076	normal	0.205321542	-0.430367769	normal	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	--	--	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Mnd1 family	Meiotic nuclear division protein 1 homolog OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: meiotic nuclear division protein 1 homolog [Condylura cristata]
ENSG00000121236(TRIM6)	--	20.92423046	1047	16.90111607	919	18.57555264	995	13.11571348	715	15.63952644	835	12.54853718	664	0.098567251	-0.580041613	normal	0.965377464	-0.159439837	normal	0.084275289	-0.59069802	normal	0.007042687	-0.440677894	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K11999|0|hsa:117854|TRIM6, RNF89; tripartite motif containing 6; K11999 tripartite motif-containing protein 6/22/34 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 6 GN=TRIM6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	tripartite motif-containing protein 6 [Equus caballus] 
ENSG00000121270(ABCC11)	--	0.045428807	4	0.033588	3	0.114743712	1	0.045335843	4	0.099675924	8	0.045119305	4	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05671|0|hsa:85320|ABCC11, EWWD, MRP8, WW; ATP-binding cassette, sub-family C (CFTR/MRP), member 11; K05671 ATP-binding cassette, subfamily C (CFTR/MRP), member 11 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter;; ABC transporter transmembrane region;; AAA domain;; RecF/RecN/SMC N terminal domain;; Type II/IV secretion system protein	ATP-binding cassette sub-family C member 11 GN=ABCC11 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: ATP-binding cassette sub-family C member 11 [Tupaia chinensis]
ENSG00000121274(PAPD5)	--	8.975005125	647	10.15921673	721	9.507152179	692	11.0151326	807	10.503005	772	9.317020225	677	0.905955289	0.287358692	normal	0.973071354	0.077018897	normal	0.97456935	-0.039819664	normal	0.663696817	0.109427942	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	K03514|0|lve:103078951|PAPD5; PAP associated domain containing 5; K03514 non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19] (A)	RNA degradation (ko03018)	[L]	"Replication, recombination and repair"	Cid1 family poly A polymerase;; Nucleotidyltransferase domain	Non-canonical poly(A) RNA polymerase PAPD5 GN=PAPD5 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: PAP-associated domain-containing protein 5 [Orcinus orca]
ENSG00000121281(ADCY7)	--	7.845144938	450	9.785130003	378	9.122366897	402	16.10814049	665	13.39593115	673	11.16002713	529	0.268476941	0.531097017	normal	0.001440883	0.808338275	normal	0.766753276	0.386509473	normal	0.001336471	0.580256443	normal	[T]	Signal transduction mechanisms	Molecular Function: adenylate cyclase activity (GO:0004016);; Cellular Component: plasma membrane (GO:0005886);; Biological Process: cAMP biosynthetic process (GO:0006171);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K08047|0|hsa:113|ADCY7, AC7; adenylate cyclase 7 (EC:4.6.1.1); K08047 adenylate cyclase 7 [EC:4.6.1.1] (A)"	Purine metabolism (ko00230);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; GABAergic synapse (ko04727);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Morphine addiction (ko05032);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[C]	Energy production and conversion	Adenylate and Guanylate cyclase catalytic domain;; Domain of Unknown Function (DUF1053)	Adenylate cyclase type 7 GN=ADCY7 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: adenylate cyclase type 7 isoform X1 [Camelus bactrianus]
ENSG00000121289(CEP89)	--	19.19153424	1412	19.604723	1466	21.58913206	1502	21.26375608	1594	21.120302	1589	18.16825	1411	0.976374361	0.143931816	normal	0.980929546	0.094713603	normal	0.980511343	-0.098356074	normal	0.858519474	0.047367807	normal	--	--	--	"K16543|0|hsa:84902|CEP89, CCDC123, CEP123; centrosomal protein 89kDa; K16543 centrosomal protein CEP89 (A)"	--	--	--	--	Centrosomal protein of 89 kDa GN=CEP89 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: centrosomal protein of 89 kDa isoform X2 [Loxodonta africana]
ENSG00000121297(TSHZ3)	--	2.053944525	228	2.113451573	232	1.80749571	194	1.942639	218	2.292372	259	1.754904607	164	0.963338129	-0.094883953	normal	0.957655938	0.136557966	normal	0.937795662	-0.248542449	normal	0.916239102	-0.05106416	normal	--	--	--	"K09236|0|hsa:57616|TSHZ3, TSH3, ZNF537; teashirt zinc finger homeobox 3; K09236 teashirt (A)"	--	--	--	"C2H2 type zinc-finger (2 copies);; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Teashirt homolog 3 GN=TSHZ3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: teashirt homolog 3 [Tupaia chinensis] 
ENSG00000121310(ECHDC2)	--	6.386105	271	6.652264	295	5.1880808	252	4.914737868	230	6.475693	282	5.677046	286	0.923349013	-0.265852894	normal	0.963386478	-0.085995401	normal	0.952566849	0.173323033	normal	0.894793169	-0.056430577	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	--	--	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family	"Enoyl-CoA hydratase domain-containing protein 2, mitochondrial (Precursor) GN=ECHDC2 OS=Homo sapiens (Human) PE=2 SV=2"	I	Lipid transport and metabolism	"PREDICTED: enoyl-CoA hydratase domain-containing protein 2, mitochondrial [Trichechus manatus latirostris]"
ENSG00000121316(PLBD1)	--	2.794748053	96	4.957747	117	2.339826614	87	1.863994927	77	2.445796	84	1.75430059	63	0.938693296	-0.342866818	normal	0.831190303	-0.491933387	normal	0.902951786	-0.464427196	normal	0.327171207	-0.443521006	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Phospholipase B	Phospholipase B-like 1 chain C (Precursor) GN=PLBD1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phospholipase B-like 1 [Oryctolagus cuniculus]
ENSG00000121318(TAS2R10)	--	0.271275	3	0.0909378	1	0.359483	3	0.347747	4	0.788298	8	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:50839|TAS2R10, T2R10, TRB2; taste receptor, type 2, member 10; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 10 GN=TAS2R10 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"taste receptor, type 2, member 10 [Canis lupus familiaris] "
ENSG00000121350(PYROXD1)	--	3.387944	213	2.9716	183	2.902662	181	2.367151	151	2.597097	163	2.696165047	170	0.602332701	-0.522635258	normal	0.951727875	-0.186761821	normal	0.963803909	-0.097902194	normal	0.446770659	-0.274506767	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[R]	General function prediction only	Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase	Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 GN=PYROXD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: pyridine nucleotide-disulfide oxidoreductase domain-containing protein 1 [Eptesicus fuscus]
ENSG00000121361(KCNJ8)	--	1.0945882	44	1.062470024	45	0.91732673	35	0.143219	6	0.0936177	3	0.05159672	2	5.88E-05	-2.622232673	down	5.16E-07	-3.383172404	down	2.47E-05	-3.384234606	down	1.14E-08	-3.519838816	down	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05001|0|ptr:740604|KCNJ8; potassium inwardly-rectifying channel, subfamily J, member 8; K05001 potassium inwardly-rectifying channel subfamily J member 8 (A)"	cGMP-PKG signaling pathway (ko04022)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	ATP-sensitive inward rectifier potassium channel 8 GN=KCNJ8 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: ATP-sensitive inward rectifier potassium channel 8 isoform X1 [Galeopterus variegatus] 
ENSG00000121380(BCL2L14)	--	0	0	0	0	0.028345426	0	0.028640324	1	0.027912723	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Apoptosis facilitator Bcl-2-like protein 14 GN=BCL2L14 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: apoptosis facilitator Bcl-2-like protein 14 [Pteropus alecto]
ENSG00000121390(PSPC1)	--	20.4823729	929	21.27414	943	19.59778682	889	21.15241007	961	23.37297562	1003	22.40188681	998	0.978767096	0.017996308	normal	0.977006867	0.067460465	normal	0.967178568	0.158310655	normal	0.751610688	0.080227947	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; NOPS (NUC059) domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Paraspeckle component 1 GN=PSPC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: paraspeckle component 1 [Oryctolagus cuniculus]
ENSG00000121406(ZNF549)	--	1.677263508	127	1.5353889	117	1.452111099	108	1.362505053	104	1.6830627	117	2.231088374	143	0.93202602	-0.314859665	normal	0.968050325	-0.021153147	normal	0.887766942	0.391908602	normal	0.974200785	0.027937976	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:256051|ZNF549; zinc finger protein 549; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 549 GN=ZNF549 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 549-like [Galeopterus variegatus] 
ENSG00000121410(A1BG)	--	3.770766614	106	2.791133443	80	3.253013167	94	2.061911203	58	3.307143853	92	2.9752414	84	0.165878462	-0.883194533	normal	0.964242031	0.177083845	normal	0.965864482	-0.167707088	normal	0.591760296	-0.278873177	normal	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	Alpha-1B-glycoprotein (Precursor) GN=A1BG OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: alpha-1B-glycoprotein [Canis lupus familiaris]
ENSG00000121413(ZSCAN18)	--	3.990240163	132	3.762869999	127	2.250168278	117	3.052222147	156	3.586870779	178	4.780924485	231	0.952342606	0.207947491	normal	0.783610446	0.460966048	normal	0.002081457	0.964058731	normal	0.068964306	0.567338897	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:65982|ZSCAN18, ZNF447; zinc finger and SCAN domain containing 18; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc finger, C2H2 type"	Zinc finger and SCAN domain-containing protein 18 GN=ZSCAN18 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger and SCAN domain-containing protein 18 isoform X1 [Galeopterus variegatus] 
ENSG00000121417(ZNF211)	--	3.825060095	205	2.742561	161	3.9432024	204	3.73375689	208	3.582954401	190	3.898194618	206	0.966947624	-0.009799731	normal	0.945604337	0.215645884	normal	0.966983073	0.005741388	normal	0.899311644	0.062576108	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:10520|ZNF211, C2H2-25, CH2H2-25, ZNF-25, ZNFC25; zinc finger protein 211; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 211 GN=ZNF211 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 211 [Galeopterus variegatus]
ENSG00000121454(LHX4)	--	3.35167	370	2.95199	329	2.53664	279	2.17049	239	2.21258	242	2.21137	244	0.081185738	-0.657918205	normal	0.644485569	-0.46202034	normal	0.946371282	-0.200512291	normal	0.061187582	-0.453334368	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09374|0|hsa:89884|LHX4, CPHD4; LIM homeobox 4; K09374 LIM homeobox protein 3/4 (A)"	--	[K]	Transcription	LIM domain;; Homeobox domain;; Homeobox KN domain	LIM/homeobox protein Lhx4 GN=LHX4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LIM/homeobox protein Lhx4 [Equus caballus] 
ENSG00000121481(RNF2)	--	10.52169325	485	8.886552982	383	9.617982177	394	7.100273826	326	9.311413481	418	7.400773438	350	0.128229006	-0.60160365	normal	0.963734256	0.104337561	normal	0.951867238	-0.178405149	normal	0.37678598	-0.227092767	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase activity (GO:0003916);; Cellular Component: chromosome (GO:0005694);; Biological Process: DNA topological change (GO:0006265);; Molecular Function: metal ion binding (GO:0046872);; 	K10695|0|mcf:102131551|RNF2; ring finger protein 2; K10695 E3 ubiquitin-protein ligase RNF1/2 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc-finger of the MIZ type in Nse subunit"	E3 ubiquitin-protein ligase RING2 GN=RNF2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RING2 isoform X1 [Myotis davidii]
ENSG00000121486(TRMT1L)	--	10.32650869	700	10.78662823	777	10.995012	759	10.59671032	720	8.865428358	629	10.99147014	756	0.975516359	0.009788537	normal	0.867666379	-0.325575374	normal	0.976319667	-0.013977189	normal	0.668966656	-0.108177533	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: tRNA (guanine-N2-)-methyltransferase activity (GO:0004809);; Biological Process: tRNA processing (GO:0008033);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	"N2,N2-dimethylguanosine tRNA methyltransferase;; Met-10+ like-protein"	TRMT1-like protein GN=TRMT1L OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: TRMT1-like protein isoform X2 [Equus przewalskii]
ENSG00000121542(SEC22A)	--	10.40026793	280	11.35293205	262	9.483360978	275	10.7616118	335	11.5145124	330	10.70140808	285	0.93720809	0.226763276	normal	0.891287863	0.309875902	normal	0.966793445	0.043006534	normal	0.519359539	0.195995936	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K08520|0|ptr:460638|SEC22A; SEC22 vesicle trafficking protein homolog A (S. cerevisiae); K08520 SEC22 vesicle trafficking protein A/C (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Regulated-SNARE-like domain	Vesicle-trafficking protein SEC22a GN=SEC22A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-trafficking protein SEC22a isoform X1 [Oryctolagus cuniculus] 
ENSG00000121552(CSTA)	--	0.342718	3	0.230319613	2	0.571362	4	0.456757	4	0.443376	3	0.787631	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K13907|6.43755e-65|ptr:746075|CSTA; cystatin A (stefin A); K13907 cystatin-A/B (A)	--	--	--	Cystatin domain	"Cystatin-A, N-terminally processed GN=CSTA OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	PREDICTED: cystatin-A [Canis lupus familiaris]
ENSG00000121577(POPDC2)	--	0.113700106	3	0.037193927	1	0.0608495	1	0.101583663	2	0.050511199	0	0.0952532	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Popeye protein conserved region	Popeye domain-containing protein 2 GN=POPDC2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	Popeye domain-containing protein 2 [Pteropus alecto]
ENSG00000121578(B4GALT4)	--	21.1134701	918	20.67394527	888	22.39936977	934	33.62837654	1437	25.999895	1150	27.7585801	1161	0.044563827	0.614833051	normal	0.839719628	0.351049091	normal	0.898576541	0.30513811	normal	0.006063301	0.430093564	normal	--	--	--	"K07969|0|hsa:8702|B4GALT4, B4Gal-T4, beta4Gal-T4; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 (EC:2.4.1.90 2.4.1.275); K07969 beta-1,4-galactosyltransferase 4 [EC:2.4.1.90 2.4.1.275 2.4.1.-] (A)"	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	N-terminal region of glycosyl transferase group 7;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	"Lactotriaosylceramide beta-1,4-galactosyltransferase GN=B4GALT4 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-galactosyltransferase 4 isoform X1 [Tupaia chinensis] "
ENSG00000121579(NAA50)	--	103.788092	3747	99.87155977	3765	114.5059573	4170	123.4333846	4666	121.6151593	4335	101.0183991	3671	0.960426499	0.285512986	normal	0.984534619	0.181887441	normal	0.98304834	-0.192091409	normal	0.675239963	0.095661383	normal	[R]	General function prediction only	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	--	--	[R]	General function prediction only	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain	N-alpha-acetyltransferase 50 GN=NAA50 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: N-alpha-acetyltransferase 50 isoform X1 [Capra hircus] 
ENSG00000121594(CD80)	--	0	0	0.021046716	1	0	0	0	0	0.0594362	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05412|0|hsa:941|CD80, B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7; CD80 molecule; K05412 CD80 antigen (A)"	Cell adhesion molecules (CAMs) (ko04514);; Toll-like receptor signaling pathway (ko04620);; Intestinal immune network for IgA production (ko04672);; Type I diabetes mellitus (ko04940);; Autoimmune thyroid disease (ko05320);; Systemic lupus erythematosus (ko05322);; Rheumatoid arthritis (ko05323);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin C1-set domain;; Immunoglobulin domain	T-lymphocyte activation antigen CD80 (Precursor) GN=CD80 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: T-lymphocyte activation antigen CD80 isoform X2 [Camelus dromedarius]
ENSG00000121621(KIF18A)	--	10.10948	668	9.19667	605	10.83475	696	12.9038	853	11.72482	796	10.24104	688	0.871671281	0.321210249	normal	0.78934549	0.373590341	normal	0.975101342	-0.024915731	normal	0.271036671	0.225561412	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10401|0|hsa:81930|KIF18A, MS-KIF18A, PPP1R99; kinesin family member 18A; K10401 kinesin family member 18/19 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF18A GN=KIF18A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF18A [Galeopterus variegatus]
ENSG00000121644(DESI2)	--	21.730391	1257	22.662343	1261	21.668527	1172	22.098725	1247	20.175708	1161	21.570311	1191	0.98149645	-0.042303533	normal	0.973384912	-0.140451252	normal	0.981431863	0.014890341	normal	0.82765297	-0.057503245	normal	--	--	--	--	--	[S]	Function unknown	PPPDE putative peptidase domain	Desumoylating isopeptidase 2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: desumoylating isopeptidase 2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000121653(MAPK8IP1)	--	6.542152189	398	7.33288076	451	7.333667533	459	5.502602248	335	6.214733692	378	5.690393994	349	0.910240614	-0.278266937	normal	0.911464088	-0.275158435	normal	0.742143224	-0.402034571	normal	0.16509237	-0.3214758	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04434|0|hsa:9479|MAPK8IP1, IB1, JIP-1, JIP1, PRKM8IP; mitogen-activated protein kinase 8 interacting protein 1; K04434 mitogen-activated protein kinase 8 interacting protein 1 (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; Variant SH3 domain;; SH3 domain	C-Jun-amino-terminal kinase-interacting protein 1 GN=MAPK8IP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: c-Jun-amino-terminal kinase-interacting protein 1 isoform X1 [Myotis lucifugus]
ENSG00000121671(CRY2)	--	2.197736848	176	2.161592	188	2.0334757	177	1.667507582	144	1.8375053	157	1.8375242	149	0.914092986	-0.317270782	normal	0.926403073	-0.27893557	normal	0.938368181	-0.254356777	normal	0.436283249	-0.286815063	normal	[L]	"Replication, recombination and repair"	--	K02295|0|ptr:742186|CRY2; cryptochrome circadian clock 2; K02295 cryptochrome (A)	Circadian rhythm (ko04710)	[LT]	"Replication, recombination and repair;; Signal transduction mechanisms"	FAD binding domain of DNA photolyase;; DNA photolyase	Cryptochrome-2 GN=CRY2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cryptochrome-2 [Pteropus alecto] 
ENSG00000121680(PEX16)	--	11.24267246	275	9.587439001	240	9.690608407	245	11.41643795	275	12.77690403	305	9.36025801	234	0.967043278	-0.030660961	normal	0.883797544	0.322541698	normal	0.96486693	-0.074096616	normal	0.847674649	0.077416379	normal	--	--	--	K13335|0|mcc:714904|PEX16; peroxisomal biogenesis factor 16; K13335 peroxin-16 (A)	Peroxisome (ko04146)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Peroxisomal membrane protein (Pex16)	Peroxisomal membrane protein PEX16 GN=PEX16 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein PEX16 [Camelus ferus]
ENSG00000121690(DEPDC7)	--	2.840772347	80	2.626830705	74	2.541924121	71	4.399551892	126	6.065771512	172	3.719982062	106	0.631731377	0.615036351	normal	0.000336433	1.179135857	up	0.787279296	0.56005749	normal	0.018294681	0.822872502	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	"Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	DEP domain-containing protein 7 GN=DEPDC7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: DEP domain-containing protein 7 [Leptonychotes weddellii]
ENSG00000121691(CAT)	--	33.5665	1368	28.3273	1152	33.7602	1369	34.2022	1403	34.0671	1385	31.651	1297	0.983193722	0.005608296	normal	0.947463735	0.244026202	normal	0.980271757	-0.086137636	normal	0.852258095	0.04971265	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: catalase activity (GO:0004096);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; 	K03781|0|hsa:847|CAT; catalase (EC:1.11.1.6); K03781 catalase [EC:1.11.1.6] (A)	Tryptophan metabolism (ko00380);; Glyoxylate and dicarboxylate metabolism (ko00630);; FoxO signaling pathway (ko04068);; Peroxisome (ko04146);; Amyotrophic lateral sclerosis (ALS) (ko05014)	[P]	Inorganic ion transport and metabolism	Catalase;; Catalase-related immune-responsive	Catalase GN=CAT OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: catalase [Pantholops hodgsonii]
ENSG00000121741(ZMYM2)	--	13.19814221	1215	14.75626493	1254	13.30350131	1170	11.71177992	1065	13.7720084	1257	10.94169707	1023	0.954185239	-0.220636856	normal	0.98160795	-0.017957626	normal	0.959683371	-0.201714769	normal	0.499438493	-0.142842335	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	MYM-type Zinc finger with FCS sequence motif;; Domain of unknown function (DUF3504)	Zinc finger MYM-type protein 2 GN=ZMYM2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger MYM-type protein 2 [Panthera tigris altaica]
ENSG00000121743(GJA3)	--	0.187328	15	0.271646	22	0.280741	22	0.123924	10	0.144673	11	0.23391	19	--	--	--	0.947883428	-0.929512282	normal	0.987360771	-0.204645662	normal	--	--	--	--	--	--	"K07612|0|hsa:2700|GJA3, CTRCT14, CX46, CZP3; gap junction protein, alpha 3, 46kDa; K07612 gap junction protein, alpha 3 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain;; Early E3 14.5 kDa protein	Gap junction alpha-3 protein GN=GJA3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: gap junction alpha-3 protein [Tupaia chinensis] 
ENSG00000121749(TBC1D15)	--	12.43938555	665	17.0974008	870	16.8807122	815	12.3930382	673	12.18082617	630	14.7964648	807	0.974799367	-0.013548983	normal	0.423280964	-0.486092512	normal	0.976989328	-0.022480907	normal	0.509389078	-0.176044519	normal	[R]	General function prediction only	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3548);; Rab-GTPase-TBC domain	TBC1 domain family member 15 GN=TBC1D15 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TBC1 domain family member 15 [Oryctolagus cuniculus]
ENSG00000121753(ADGRB2)	--	8.181921697	790	5.18045117	522	7.437835827	746	6.447640822	588	7.158776488	698	4.522262389	429	0.52889844	-0.455836917	normal	0.738034479	0.396753549	normal	0.000985891	-0.80431137	normal	0.514031579	-0.284587183	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04597|0|mcf:102134261|BAI2; brain-specific angiogenesis inhibitor 2; K04597 brain-specific angiogenesis inhibitor 2 (A)	--	--	--	7 transmembrane receptor (Secretin family);; Domain of unknown function (DUF3497);; Thrombospondin type 1 domain;; Latrophilin/CL-1-like GPS domain	Brain-specific angiogenesis inhibitor 2 (Precursor) GN=BAI2 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: brain-specific angiogenesis inhibitor 2 isoform X1 [Galeopterus variegatus]
ENSG00000121764(HCRTR1)	--	0.123993245	4	0	0	0	0	0	0	0.07952881	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04238|0|hsa:3061|HCRTR1, OX1R; hypocretin (orexin) receptor 1; K04238 hypocretin (orexin) receptor 1 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Orexin receptor type 1 GN=HCRTR1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: orexin receptor type 1 [Tursiops truncatus]
ENSG00000121766(ZCCHC17)	--	12.0569136	411	12.26259249	423	11.07455431	373	14.6529403	505	13.45465291	455	12.126291	414	0.917666677	0.265416385	normal	0.966514353	0.083494475	normal	0.959530707	0.141618474	normal	0.543384551	0.164957675	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	S1 RNA binding domain	Nucleolar protein of 40 kDa GN=ZCCHC17 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pre-mRNA-splicing factor ATP-dependent RNA helicase prp22 isoform X1 [Canis lupus familiaris]
ENSG00000121769(FABP3)	--	0	0	0.0936129	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08752|3.37337e-91|ptr:456699|FABP3; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); K08752 fatty acid-binding protein 3, muscle and heart (A)"	PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin / cytosolic fatty-acid binding protein family	"Fatty acid-binding protein, heart GN=FABP3 OS=Homo sapiens (Human) PE=1 SV=4"	I	Lipid transport and metabolism	"PREDICTED: fatty acid-binding protein, heart [Oryctolagus cuniculus]"
ENSG00000121774(KHDRBS1)	--	94.1757	4544	98.27092	4776	91.70043	4431	110.28943	5339	99.28512	4773	93.55303001	4521	0.984615763	0.20171148	normal	0.992880294	-0.022325987	normal	0.992745241	0.020711151	normal	0.786374162	0.067875902	normal	[A]	RNA processing and modification	Molecular Function: RNA binding (GO:0003723);; 	"K13198|0|ocu:100350854|KHDRBS1; KH domain containing, RNA binding, signal transduction associated 1; K13198 KH domain-containing, RNA-binding, signal transduction-associated protein 1 (A)"	--	[A]	RNA processing and modification	KH domain;; KH domain	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens (Human) PE=1 SV=1"	A	RNA processing and modification	"PREDICTED: KH domain-containing, RNA-binding, signal transduction-associated protein 1 [Oryctolagus cuniculus]"
ENSG00000121775(TMEM39B)	--	7.425980156	210	7.421334724	202	7.493547922	221	6.213457	172	6.271262626	180	7.412520093	214	0.905493318	-0.316251318	normal	0.950721998	-0.186306378	normal	0.965853869	-0.054349054	normal	0.630235954	-0.181807061	normal	--	--	--	--	--	[S]	Function unknown	Putative transmembrane protein	Transmembrane protein 39B GN=TMEM39B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 39B isoform 2 [Ceratotherium simum simum]
ENSG00000121797(CCRL2)	--	0	0	0	0	0	0	0.0347528	1	0.410471567	11	0.034696605	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08373|0|hsa:9034|CCRL2, ACKR5, CKRX, CRAM, CRAM-A, CRAM-B, HCR; chemokine (C-C motif) receptor-like 2; K08373 C-C chemokine receptor-like 2 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	C-C chemokine receptor-like 2 GN=CCRL2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C-C chemokine receptor-like 2 isoform X1 [Galeopterus variegatus]
ENSG00000121851(POLR3GL)	--	10.63099937	222	8.938620008	183	7.1433033	159	9.17964635	199	10.6356532	221	10.59235828	225	0.950972108	-0.187253781	normal	0.933500928	0.248902168	normal	0.672768046	0.488680864	normal	0.653133349	0.172439218	normal	--	--	Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription from RNA polymerase III promoter (GO:0006383);; 	"K03024|1.2196e-86|hsa:84265|POLR3GL, RPC32HOM, flj32422; polymerase (RNA) III (DNA directed) polypeptide G (32kD)-like; K03024 DNA-directed RNA polymerase III subunit RPC7 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	--	--	DNA-directed RNA polymerase III subunit Rpc31	DNA-directed RNA polymerase III subunit RPC7-like GN=POLR3GL OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC7-like isoform X1 [Tupaia chinensis] 
ENSG00000121853(GHSR)	--	0	0	0	0	0	0	0.089198388	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	K04284|0|ptr:460851|GHSR; growth hormone secretagogue receptor; K04284 growth hormone secretagogue receptor (A)	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srw;; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv	Growth hormone secretagogue receptor type 1 GN=GHSR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	growth hormone secretagogue receptor type 1 [Oryctolagus cuniculus] 
ENSG00000121858(TNFSF10)	--	0.3101292	11	0.3327901	12	0.2062322	6	0.476772723	18	0.5505375	20	0.368230277	14	--	--	--	0.977837051	0.651414772	normal	--	--	--	--	--	--	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	K04721|0|ggo:101130096|TNFSF10; tumor necrosis factor ligand superfamily member 10 isoform 1; K04721 tumor necrosis factor ligand superfamily member 10 (A)	Cytokine-cytokine receptor interaction (ko04060);; FoxO signaling pathway (ko04068);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; Measles (ko05162);; Influenza A (ko05164)	--	--	TNF(Tumour Necrosis Factor) family	Tumor necrosis factor ligand superfamily member 10 GN=TNFSF10 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"tumor necrosis factor (ligand) superfamily, member 10 [Equus caballus] "
ENSG00000121864(ZNF639)	--	12.52230246	382	11.61651755	353	11.85745221	366	11.83201975	389	11.53331696	364	9.60180438	314	0.969389622	-0.004616348	normal	0.967789002	0.022747741	normal	0.936402428	-0.228350806	normal	0.856924787	-0.067056559	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc-finger domain"	Zinc finger protein 639 GN=ZNF639 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 639 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000121871(SLITRK3)	--	0	0	0	0	0	0	0	0	0.025045049	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	SLIT and NTRK-like protein 3 (Precursor) GN=SLITRK3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: SLIT and NTRK-like protein 3 isoform X1 [Leptonychotes weddellii] 
ENSG00000121879(PIK3CA)	--	3.130418362	373	3.762724546	450	3.21519931	441	3.001694874	427	3.136996855	442	2.991752478	421	0.955411331	0.163598025	normal	0.968908364	-0.047145321	normal	0.967863673	-0.074986653	normal	0.987130828	0.008255178	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; 	"K00922|0|ptr:460858|PIK3CA; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; K00922 phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153] (A)"	Inositol phosphate metabolism (ko00562);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; Carbohydrate digestion and absorption (ko04973);; Bacterial invasion of epithelial cells (ko05100);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	"Phosphoinositide 3-kinase family, accessory domain (PIK domain);; Phosphatidylinositol 3- and 4-kinase;; PI3-kinase family, ras-binding domain;; Phosphoinositide 3-kinase C2;; PI3-kinase family, p85-binding domain"	"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform GN=PIK3CA OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform [Bos taurus] "
ENSG00000121892(PDS5A)	--	27.64234	3286	25.4875	3049	28.40043	3405	25.61785	3130	27.59885	3152	24.693794	2966	0.988591114	-0.100953713	normal	0.990050929	0.026491903	normal	0.977758035	-0.207328896	normal	0.670642153	-0.095964474	normal	--	--	--	"K11267|0|hsa:23244|PDS5A, SCC-112, SCC112; PDS5 cohesin associated factor A; K11267 sister chromatid cohesion protein PDS5 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: sister chromatid cohesion protein PDS5 homolog A isoform X1 [Galeopterus variegatus] 
ENSG00000121895(TMEM156)	--	18.0672153	629	22.817297	815	22.8021209	723	17.602248	604	16.589892	567	27.971104	980	0.97035457	-0.089121548	normal	0.22004898	-0.543661282	normal	0.621639245	0.42971977	normal	0.967999994	-0.03048233	normal	--	--	--	--	--	--	--	TMEM156 protein family	Transmembrane protein 156 GN=TMEM156 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 156 [Balaenoptera acutorostrata scammoni]
ENSG00000121897(LIAS)	--	6.361854	157	6.48490908	160	5.186408179	122	5.080440706	140	5.2249594	162	5.14653162	127	0.954165572	-0.194156421	normal	0.966275233	-0.003472037	normal	0.968328137	0.049059836	normal	0.926977546	-0.055057071	normal	[H]	Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	"K03644|0|ggo:101135272|LIAS; lipoyl synthase, mitochondrial isoform 1; K03644 lipoic acid synthetase [EC:2.8.1.8] (A)"	Lipoic acid metabolism (ko00785)	[H]	Coenzyme transport and metabolism	Radical SAM superfamily	"Lipoyl synthase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03123} (Precursor) GN=HUSSY-01 OS=Homo sapiens (Human) PE=1 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: lipoyl synthase, mitochondrial isoform X1 [Oryctolagus cuniculus]"
ENSG00000121898(CPXM2)	--	0	0	0	0	0	0	0.0131775	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	"K08639|0|hsa:119587|CPXM2, CPX2, UNQ676; carboxypeptidase X (M14 family), member 2; K08639 carboxypeptidase X2 (A)"	--	[R]	General function prediction only	Zinc carboxypeptidase;; F5/8 type C domain;; Carboxypeptidase regulatory-like domain	Inactive carboxypeptidase-like protein X2 (Precursor) GN=CPXM2 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	"PREDICTED: inactive carboxypeptidase-like protein X2, partial [Balaenoptera acutorostrata scammoni]"
ENSG00000121900(TMEM54)	--	34.170427	404	35.19857433	454	35.01298708	421	35.505597	450	49.61392343	582	36.67179154	461	0.962614875	0.124289449	normal	0.853120855	0.335909838	normal	0.963316705	0.122235347	normal	0.417583443	0.202149169	normal	--	--	--	--	--	--	--	Beta-casein like protein	Transmembrane protein 54 GN=TMEM54 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 54 isoform X4 [Canis lupus familiaris]
ENSG00000121903(ZSCAN20)	--	1.019364228	168	1.320143343	193	1.457711159	170	1.290884839	170	1.166351049	150	1.326475882	173	0.967330918	-0.013634793	normal	0.861790888	-0.381662826	normal	0.967209828	0.016797721	normal	0.777925229	-0.12845392	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:7579|ZSCAN20, KOX29, ZFP-31, ZNF31, ZNF360; zinc finger and SCAN domain containing 20; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; Myb/SANT-like DNA-binding domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Myb-like DNA-binding domain;; Myb/SANT-like DNA-binding domain"	Zinc finger and SCAN domain-containing protein 20 GN=ZSCAN20 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 20 [Ceratotherium simum simum]
ENSG00000121904(CSMD2)	--	0	0	0	0	0	0	0.041431524	3	0.010410597	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17495|0|hsa:114784|CSMD2, dJ1007G16.1, dJ1007G16.2, dJ947L8.1; CUB and Sushi multiple domains 2; K17495 CUB and sushi domain-containing protein (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	CUB domain;; Sushi domain (SCR repeat);; CUB-like domain	CUB and sushi domain-containing protein 2 GN=CSMD2 OS=Homo sapiens (Human) PE=1 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: LOW QUALITY PROTEIN: CUB and sushi domain-containing protein 2 [Mustela putorius furo]
ENSG00000121905(HPCA)	--	0.46489	12	0.423142	11	0.485686	12	0.154194	4	0.300957	7	0.228075	6	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region;; Cytoskeletal-regulatory complex EF hand	Neuron-specific calcium-binding protein hippocalcin GN=HPCA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuron-specific calcium-binding protein hippocalcin isoformX2 [Canis lupus familiaris]
ENSG00000121931(LRIF1)	--	15.28339343	610	16.513222	686	15.74203471	619	14.313377	584	14.41543223	593	16.04543049	651	0.969595654	-0.093432587	normal	0.939057733	-0.231054611	normal	0.972584951	0.06427356	normal	0.751610688	-0.088053251	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: retinoic acid receptor binding (GO:0042974);; "	--	--	--	--	--	Ligand-dependent nuclear receptor-interacting factor 1 GN=LRIF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ligand-dependent nuclear receptor-interacting factor 1 [Ceratotherium simum simum]
ENSG00000121940(CLCC1)	--	10.34774401	788	14.95586757	968	13.25535283	891	12.50792862	924	11.53853651	834	13.75642663	889	0.955892669	0.198507256	normal	0.943187445	-0.235988593	normal	0.978219302	-0.01151389	normal	0.951471013	-0.021363129	normal	--	--	--	--	--	--	--	Mid-1-related chloride channel (MCLC)	Chloride channel CLIC-like protein 1 (Precursor) GN=CLCC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: chloride channel CLIC-like protein 1 [Galeopterus variegatus] 
ENSG00000121957(GPSM2)	--	8.710900923	422	7.472239547	403	6.612345	401	7.140391886	357	6.727413	380	7.7369206	410	0.914385834	-0.271076599	normal	0.96339783	-0.105798043	normal	0.969663618	0.023642053	normal	0.705643346	-0.11689981	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: GTPase regulator activity (GO:0030695);; Molecular Function: identical protein binding (GO:0042802);; 	"K15837|0|hsa:29899|GPSM2, CMCS, DFNB82, LGN, PINS; G-protein signaling modulator 2; K15837 G-protein signaling modulator 2 (A)"	--	[T]	Signal transduction mechanisms	GoLoco motif;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Rapsyn N-terminal myristoylation and linker region	G-protein-signaling modulator 2 GN=GPSM2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: G-protein-signaling modulator 2 isoform X1 [Galeopterus variegatus]
ENSG00000121964(GTDC1)	--	6.813497864	161	6.571570968	169	4.567005509	206	2.842068302	122	5.088757511	158	3.764040772	136	0.842612912	-0.426321241	normal	0.961300008	-0.117438119	normal	0.400080455	-0.601851862	normal	0.25909667	-0.38602019	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF3524);; Glycosyl transferases group 1;; Glycosyl transferases group 1	Glycosyltransferase-like domain-containing protein 1 GN=GTDC1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: glycosyltransferase-like domain-containing protein 1 isoform X1 [Galeopterus variegatus] 
ENSG00000121966(CXCR4)	--	0.432005142	10	0.129868734	3	0.428895619	9	1.764831919	41	0.586436346	13	2.697182728	63	0.020093735	1.8542766	normal	--	--	--	5.35E-07	2.609899469	up	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: cytokine binding (GO:0019955);; 	"K04189|0|hsa:7852|CXCR4, CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM; chemokine (C-X-C motif) receptor 4; K04189 C-X-C chemokine receptor type 4 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Axon guidance (ko04360);; Leukocyte transendothelial migration (ko04670);; Intestinal immune network for IgA production (ko04672);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; CXCR4 Chemokine receptor N terminal;; Serpentine type 7TM GPCR chemoreceptor Srsx	C-X-C chemokine receptor type 4 GN=CXCR4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	c-X-C chemokine receptor type 4 [Tupaia chinensis] 
ENSG00000121988(ZRANB3)	--	2.3613401	202	2.531380449	221	2.5341528	216	1.44103456	127	1.342999	122	1.787093	159	0.177659875	-0.693641152	normal	0.012760358	-0.870452998	normal	0.764758238	-0.446636717	normal	0.018220851	-0.667770307	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: endonuclease activity (GO:0004519);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	--	--	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; HNH endonuclease;; Zn-finger in Ran binding protein and others;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase"	Endonuclease ZRANB3 GN=ZRANB3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: DNA annealing helicase and endonuclease ZRANB3 [Orcinus orca]
ENSG00000121989(ACVR2A)	--	2.025967	141	2.477510004	167	2.065155	144	1.459743	105	1.496514467	117	1.481585	115	0.839786485	-0.450427456	normal	0.677507954	-0.529010849	normal	0.920270712	-0.328853417	normal	0.221316865	-0.444610753	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K04670|0|pon:100435220|ACVR2A; activin A receptor, type IIA; K04670 activin receptor type-2A [EC:2.7.11.30] (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Activin types I and II receptor domain	Activin receptor type-2A (Precursor) GN=ACVR2A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: activin receptor type-2A isoform X2 [Galeopterus variegatus]
ENSG00000122008(POLK)	--	8.665846021	669	8.988562	759	9.860625581	776	9.75357	742	7.882894236	662	10.9399083	766	0.968967828	0.118322619	normal	0.945949135	-0.218229211	normal	0.976309821	-0.026950838	normal	0.888514103	-0.043450349	normal	[L]	"Replication, recombination and repair"	Molecular Function: damaged DNA binding (GO:0003684);; Biological Process: DNA repair (GO:0006281);; 	"K03511|0|hsa:51426|POLK, DINB1, DINP, POLQ; polymerase (DNA directed) kappa (EC:2.7.7.7); K03511 DNA polymerase kappa [EC:2.7.7.7] (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	impB/mucB/samB family;; impB/mucB/samB family C-terminal domain;; IMS family HHH motif	DNA polymerase kappa GN=POLK OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase kappa [Ceratotherium simum simum]
ENSG00000122025(FLT3)	--	0.0287829	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05092|0|hsa:2322|FLT3, CD135, FLK-2, FLK2, STK1; fms-related tyrosine kinase 3 (EC:2.7.10.1); K05092 fms-related tyrosine kinase 3 [EC:2.7.10.1] (A)"	Cytokine-cytokine receptor interaction (ko04060);; Hematopoietic cell lineage (ko04640);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Acute myeloid leukemia (ko05221);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	Receptor-type tyrosine-protein kinase FLT3 (Precursor) GN=FLT3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	FL cytokine receptor precursor [Canis lupus familiaris] 
ENSG00000122026(RPL21)	--	571.2231614	5703	579.9875711	5791	545.958618	5413	622.1491299	6311	584.2045253	5737	554.94467	5527	0.99251809	0.115285795	normal	0.993772416	-0.034933371	normal	0.993802946	0.021770763	normal	0.903207025	0.034185662	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02889|3.29356e-114|ssc:100736809|RPL21; ribosomal protein L21; K02889 large subunit ribosomal protein L21e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L21e	60S ribosomal protein L21 GN=RPL21 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L21 isoform X1 [Monodelphis domestica] 
ENSG00000122033(MTIF3)	--	11.91722713	203	12.27572751	207	12.67611647	214	9.158066128	159	11.5133396	196	13.30114	223	0.859402711	-0.380025932	normal	0.961928752	-0.099456826	normal	0.966000898	0.050789852	normal	0.748845921	-0.13056017	normal	--	--	Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	"K02520|0|hsa:219402|MTIF3, IF3mt; mitochondrial translational initiation factor 3; K02520 translation initiation factor IF-3 (A)"	--	--	--	"Translation initiation factor IF-3, C-terminal domain;; Translation initiation factor IF-3, N-terminal domain"	"Translation initiation factor IF-3, mitochondrial (Precursor) GN=MTIF3 OS=Homo sapiens (Human) PE=1 SV=4"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: translation initiation factor IF-3, mitochondrial isoform X1 [Tupaia chinensis] "
ENSG00000122034(GTF3A)	--	48.6873	1219	48.6221	1210	50.0159	1249	50.6665	1275	51.4201	1291	48.56720006	1223	0.981663864	0.033925048	normal	0.979866845	0.071968308	normal	0.981503807	-0.038593291	normal	0.946746066	0.021653738	normal	[R]	General function prediction only	--	"K09191|0|hsa:2971|GTF3A, AP2, TFIIIA; general transcription factor IIIA; K09191 general transcription factor IIIA (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding"	Transcription factor IIIA GN=GTF3A OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor IIIA [Ceratotherium simum simum]
ENSG00000122035(RASL11A)	--	1.41432	33	0.929089	22	1.1767	28	1.45884	35	0.452454	10	0.457088	11	0.983640868	0.051718444	normal	0.927170538	-1.049570928	normal	0.765910034	-1.245548116	normal	0.53719273	-0.593034776	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07852|9.38956e-165|ggo:101153796|RASL11A; ras-like protein family member 11A; K07852 Ras-like protein family member 11A (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein	Ras-like protein family member 11A OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ras-like protein family member 11A [Ceratotherium simum simum]
ENSG00000122042(UBL3)	--	7.05615	433	7.30094	449	6.5843	401	9.04014	564	10.1169	623	9.90625	612	0.831616284	0.349406917	normal	0.587848942	0.449798847	normal	0.105069849	0.599793765	normal	0.014041825	0.466587823	normal	--	--	--	--	--	--	--	Ubiquitin-2 like Rad60 SUMO-like	Ubiquitin-like protein 3 (Precursor) GN=UBL3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ubiquitin-like protein 3-like [Pantholops hodgsonii]
ENSG00000122068(FYTTD1)	--	10.986898	783	9.248599893	793	9.641964	795	12.15850786	1049	12.11651513	929	11.14635525	915	0.744234506	0.390434297	normal	0.953391696	0.206566914	normal	0.957328193	0.194180874	normal	0.152032823	0.265447278	normal	--	--	--	--	--	--	--	Forty-two-three protein	UAP56-interacting factor GN=FYTTD1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: UAP56-interacting factor isoform X1 [Galeopterus variegatus]
ENSG00000122085(MTERF4)	--	10.31400282	421	10.89173045	437	11.778228	438	8.045406	281	7.716029132	271	10.454783	389	0.133126261	-0.611331125	normal	0.028411278	-0.707626142	normal	0.952373365	-0.178796678	normal	0.023650128	-0.482003949	normal	--	--	"Molecular Function: double-stranded DNA binding (GO:0003690);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15032|0|hsa:130916|MTERF4, MTERFD2; mitochondrial transcription termination factor 4; K15032 mTERF domain-containing protein, mitochondrial (A)"	--	--	--	mTERF	mTERF domain-containing protein 2 processed (Precursor) GN=MTERF4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: mTERF domain-containing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000122122(SASH3)	--	0.018194	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Lymphocyte signaling adaptor protein;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Variant SH3 domain	SAM and SH3 domain-containing protein 3 GN=SASH3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SAM and SH3 domain-containing protein 3 [Lipotes vexillifer]
ENSG00000122126(OCRL)	--	21.06966076	1989	20.15920321	1890	20.03714	1864	22.45893028	2120	22.6168399	2122	20.6191943	1947	0.986135525	0.061142975	normal	0.979907978	0.145501945	normal	0.985629624	0.054516303	normal	0.707684786	0.086422566	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K01099|0|hsa:4952|OCRL, INPP5F, LOCR, NPHL2, OCRL-1, OCRL1; oculocerebrorenal syndrome of Lowe (EC:3.1.3.36); K01099 phosphatidylinositol-bisphosphatase [EC:3.1.3.36] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endonuclease/Exonuclease/phosphatase family;; RhoGAP domain	Inositol polyphosphate 5-phosphatase OCRL-1 GN=OCRL OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: inositol polyphosphate 5-phosphatase OCRL-1 isoform 1 [Ceratotherium simum simum]
ENSG00000122133(PAEP)	--	0	0	0	0	0	0	0	0	0.412420231	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lipocalin / cytosolic fatty-acid binding protein family	Glycodelin (Precursor) GN=PAEP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: beta-lactoglobulin-1-like [Canis lupus familiaris]
ENSG00000122140(MRPS2)	--	51.332064	1440	43.94961088	1230	48.828058	1391	44.490928	1252	52.46549048	1482	44.43874115	1263	0.953440236	-0.232400303	normal	0.947711438	0.247183372	normal	0.974174216	-0.147390984	normal	0.873271495	-0.043886338	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02967|0|hsa:51116|MRPS2, MRP-S2, S2mt; mitochondrial ribosomal protein S2; K02967 small subunit ribosomal protein S2 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S2	"28S ribosomal protein S2, mitochondrial GN=MRPS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S2, mitochondrial [Trichechus manatus latirostris]"
ENSG00000122176(FMOD)	--	0	0	0.0157696	1	0	0	0	0	0.0153279	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K08121|0|ptr:457644|FMOD; fibromodulin; K08121 fibromodulin (A)	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Fibromodulin (Precursor) GN=FMOD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	fibromodulin precursor [Equus caballus] 
ENSG00000122188(LAX1)	--	0	0	0	0	0.01710031	0	0.017287055	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: immune response (GO:0006955);; Biological Process: regulation of lymphocyte activation (GO:0051249);; 	--	--	--	--	--	Lymphocyte transmembrane adapter 1 GN=LAX1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: lymphocyte transmembrane adapter 1 [Ceratotherium simum simum]
ENSG00000122194(PLG)	--	0.117813713	7	0.168673856	10	0.116780236	6	0.406640835	24	0.787636329	46	0.534644306	32	0.661531178	1.553718759	normal	0.002382126	2.025448273	up	0.023294489	2.150096256	normal	0.000362839	2.127995373	up	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	K01315|0|hsa:5340|PLG; plasminogen (EC:3.4.21.7); K01315 plasminogen [EC:3.4.21.7] (A)	Neuroactive ligand-receptor interaction (ko04080);; Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150);; Influenza A (ko05164)	--	--	Kringle domain;; Trypsin;; PAN domain;; Domain of unknown function (DUF1986)	Plasmin light chain B (Precursor) GN=PLG OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: plasminogen-like [Mustela putorius furo] 
ENSG00000122203(KIAA1191)	--	40.40925168	1942	35.423771	1598	37.1830619	1698	41.18580333	2004	43.7161908	2074	30.19980763	1434	0.986695121	0.014495755	normal	0.862327246	0.354426774	normal	0.948922907	-0.251838499	normal	0.895946735	0.051490802	normal	--	--	--	--	--	--	--	P33 mono-oxygenase	Putative monooxygenase p33MONOX GN=KIAA1191 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: putative monooxygenase p33MONOX isoform X1 [Felis catus]
ENSG00000122218(COPA)	--	45.75517	4519	45.57962	4538	44.25362	4362	57.17208	5637	59.57035	5839	56.6381	5584	0.964345918	0.28800393	normal	0.933632825	0.342137396	normal	0.923250722	0.347910864	normal	0.04965538	0.325079929	normal	[R]	General function prediction only	Molecular Function: structural molecule activity (GO:0005198);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: COPI vesicle coat (GO:0030126);; 	"K05236|0|hsa:1314|COPA, HEP-COP; coatomer protein complex, subunit alpha; K05236 coatomer protein complex, subunit alpha (xenin) (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Coatomer (COPI) alpha subunit C-terminus;; Coatomer WD associated region;; WD domain, G-beta repeat"	Proxenin GN=COPA OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit alpha isoform X1 [Galeopterus variegatus]
ENSG00000122224(LY9)	--	0	0	0	0	0	0	0.101643118	5	0.060692281	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06570|0|pon:100437582|LY9; lymphocyte antigen 9; K06570 lymphocyte antigen 9 (A)	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain	T-lymphocyte surface antigen Ly-9 (Precursor) GN=LY9 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: T-lymphocyte surface antigen Ly-9 isoform 1 [Ceratotherium simum simum]
ENSG00000122257(RBBP6)	--	13.37959433	1535	12.73932379	1516	11.60257373	1432	12.77986924	1612	12.57050596	1510	12.24574288	1295	0.9840615	0.039742007	normal	0.983528662	-0.027120654	normal	0.973734446	-0.153200624	normal	0.87705965	-0.04333045	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein ubiquitination (GO:0016567);; 	"K10624|0|hsa:5930|RBBP6, MY038, P2P-R, PACT, RBQ-1, SNAMA; retinoblastoma binding protein 6; K10624 E3 ubiquitin-protein ligase RBBP6 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"DWNN domain;; Zinc finger, C3HC4 type (RING finger);; U-box domain;; Zinc knuckle"	E3 ubiquitin-protein ligase RBBP6 GN=RBBP6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RBBP6 isoform X2 [Equus przewalskii]
ENSG00000122299(ZC3H7A)	--	16.18649373	1109	18.69962232	1170	15.84652615	1075	14.63592842	993	16.11977349	1064	17.29611149	1019	0.961976882	-0.189947709	normal	0.969454263	-0.158222379	normal	0.97734686	-0.085350708	normal	0.492909278	-0.146020818	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	TPR repeat;; Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 7A GN=ZC3H7A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger CCCH domain-containing protein 7A [Vicugna pacos]
ENSG00000122335(SERAC1)	--	3.941701948	209	4.677004149	225	3.431249108	196	3.871610117	209	3.52148061	206	3.927603301	195	0.966625497	-0.03060726	normal	0.956377909	-0.147669505	normal	0.966944228	-0.01555068	normal	0.887313641	-0.068122698	normal	--	--	--	--	--	[S]	Function unknown	PGAP1-like protein	Protein SERAC1 GN=SERAC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein SERAC1 [Equus przewalskii]
ENSG00000122359(ANXA11)	--	72.3765329	3982	74.04087804	4140	72.12138597	4017	63.80212462	3588	66.80712502	3794	60.37879645	3420	0.984035758	-0.181071946	normal	0.987478148	-0.147281424	normal	0.973167758	-0.240315414	normal	0.31507974	-0.189665833	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	K17095|0|ptr:450553|ANXA11; annexin A11; K17095 annexin A7/11 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A11 GN=ANXA11 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	Annexin A11 [Tupaia chinensis]
ENSG00000122367(LDB3)	--	0.081978493	6	0.067904671	6	0.039033682	3	0.082251397	6	0.05250048	3	0.087812367	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain;; PDZ domain (Also known as DHR or GLGF)	LIM domain-binding protein 3 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: LIM domain-binding protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000122375(OPN4)	--	0	0	0	0	0	0	0	0	0	0	0.047942002	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Melanopsin GN=OPN4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: melanopsin [Galeopterus variegatus]
ENSG00000122376(FAM35A)	--	31.470203	1274	32.35409527	1305	36.06166681	1369	28.091018	1223	34.76570374	1366	31.0892863	1249	0.979185475	-0.089662758	normal	0.981754414	0.044430793	normal	0.974914873	-0.140477883	normal	0.809852786	-0.061736009	normal	--	--	--	--	--	--	--	--	Protein FAM35A GN=FAM35A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM35A isoform X1 [Pteropus alecto] 
ENSG00000122378(FAM213A)	--	83.67522441	2580	96.61330188	2895	92.69332252	2942	70.28779562	2186	65.0906113	2087	93.19731573	2873	0.951783448	-0.26973517	normal	0.427015379	-0.49325436	normal	0.989623649	-0.042508583	normal	0.25197642	-0.25645931	normal	--	--	--	--	--	[S]	Function unknown	AhpC/TSA antioxidant enzyme	Redox-regulatory protein FAM213A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: redox-regulatory protein FAM213A isoform X1 [Galeopterus variegatus] 
ENSG00000122386(ZNF205)	--	7.12370038	263	7.757529751	272	7.2482641	284	6.06528	228	5.60231896	204	7.507876847	273	0.936194872	-0.235382767	normal	0.745130099	-0.433669479	normal	0.965754935	-0.064928753	normal	0.443009853	-0.236836978	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7755|ZNF205, RhitH, ZNF210, Zfp13; zinc finger protein 205; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc-finger of C2H2 type"	Zinc finger protein 205 GN=ZNF205 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 205 [Ursus maritimus] 
ENSG00000122390(NAA60)	--	27.25268765	1107	27.75830103	1169	28.26294662	1179	28.06537179	1167	32.05978124	1348	35.05467253	1470	0.980288875	0.045255899	normal	0.966476679	0.183897322	normal	0.90193474	0.30960466	normal	0.34006272	0.185469719	normal	[R]	General function prediction only	"Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	--	--	[R]	General function prediction only	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; FR47-like protein	N-alpha-acetyltransferase 60 GN=NAA60 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: N-alpha-acetyltransferase 60 [Odobenus rosmarus divergens]
ENSG00000122406(RPL5)	--	613.71	9237	609.071	9413	588.082	9041	673.385	10528	643.924	9607	618.947	9434	0.993617127	0.157878248	normal	0.99593666	0.008003562	normal	0.995741896	0.053087111	normal	0.782747644	0.07306659	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; Molecular Function: 5S rRNA binding (GO:0008097);; 	K02932|0|pbi:103061998|RPL5; ribosomal protein L5; K02932 large subunit ribosomal protein L5e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L18p/L5e family;; Ribosomal L18 C-terminal region	60S ribosomal protein L5 GN=RPL5 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L5-like [Panthera tigris altaica]
ENSG00000122417(ODF2L)	--	6.667302817	310	6.932305008	367	8.125442299	365	10.25745104	457	5.888563999	396	7.815371551	445	0.353013698	0.526930828	normal	0.964914575	0.087944894	normal	0.910991496	0.276578015	normal	0.2150146	0.295704617	normal	--	--	--	--	--	--	--	--	Outer dense fiber protein 2-like GN=ODF2L OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: outer dense fiber protein 2-like isoform X5 [Galeopterus variegatus]
ENSG00000122420(PTGFR)	--	0.016617994	1	0	0	0	0	0.032808497	2	0.032114546	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04262|0|hsa:5737|PTGFR, FP; prostaglandin F receptor (FP); K04262 prostaglandin F receptor (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	"7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv;; Caenorhabditis serpentine receptor-like protein, class xa"	Prostaglandin F2-alpha receptor GN=PTGFR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: prostaglandin F2-alpha receptor [Odobenus rosmarus divergens]
ENSG00000122432(SPATA1)	--	0.0195723	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Spermatogenesis-associated protein 1 GN=SPATA1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: spermatogenesis-associated protein 1 [Galeopterus variegatus]
ENSG00000122435(TRMT13)	--	5.0101014	254	4.734959287	280	4.435640024	273	5.436609921	296	4.642227096	269	4.07207202	284	0.948963059	0.188877334	normal	0.963739023	-0.078812883	normal	0.966561698	0.048435464	normal	0.902702768	0.051864438	normal	--	--	Biological Process: tRNA processing (GO:0008033);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K15446|0|hsa:54482|TRMT13, CCDC76; tRNA methyltransferase 13 homolog (S. cerevisiae) (EC:2.1.1.225); K15446 tRNA:m4X modification enzyme [EC:2.1.1.225] (A)"	--	[S]	Function unknown	Methyltransferase TRM13;; CCCH zinc finger in TRM13 protein;; U11-48K-like CHHC zinc finger	tRNA:m(4)X modification enzyme TRM13 homolog GN=TRMT13 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: tRNA:m(4)X modification enzyme TRM13 homolog [Galeopterus variegatus]
ENSG00000122477(LRRC39)	--	0.357027779	12	0.204750259	7	0.493460926	16	0.542144019	19	0.543328701	18	0.370719	13	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 39 GN=LRRC39 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 39 [Ceratotherium simum simum]
ENSG00000122481(RWDD3)	--	20.06430015	1257	24.61229182	1501	21.1666223	1318	26.59723855	1807	22.178874	1437	27.96694611	2011	0.369297742	0.492275317	normal	0.981129849	-0.084203757	normal	0.057518766	0.600709231	normal	0.149397525	0.34545583	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	RWD domain	RWD domain-containing protein 3 GN=RWDD3 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: RWD domain-containing protein 3 [Camelus dromedarius]
ENSG00000122482(ZNF644)	--	7.10269737	605	9.232411418	746	8.095037947	623	7.195510545	742	7.382912423	743	7.357840345	695	0.922639808	0.263047751	normal	0.975267044	-0.027184758	normal	0.963621609	0.149146445	normal	0.624077398	0.121652966	normal	--	--	--	--	--	[R]	General function prediction only	C2H2-type zinc finger	Zinc finger protein 644 GN=ZNF644 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 644 isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000122483(CCDC18)	--	4.0968339	462	3.660617	410	5.403852	446	3.7972282	423	4.258666	449	4.0227372	456	0.95742306	-0.157519728	normal	0.963803862	0.10927972	normal	0.970600705	0.023619466	normal	0.985016047	-0.009975769	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 18 GN=CCDC18 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 18 isoform 1 [Ceratotherium simum simum]
ENSG00000122484(RPAP2)	--	2.53862	491	4.54446	530	2.381638	411	3.22581	607	2.99866	589	2.9646	588	0.912546456	0.274367917	normal	0.963872877	0.130495394	normal	0.372819436	0.506819181	normal	0.15967395	0.29540467	normal	--	--	--	--	--	[S]	Function unknown	Rtr1/RPAP2 family	Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 GN=RPAP2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 [Myotis lucifugus]
ENSG00000122490(PQLC1)	--	9.384762	403	7.840202	355	8.755248286	415	12.88233164	572	12.802024	552	10.426049	472	0.502904365	0.47288303	normal	0.104060381	0.613311695	normal	0.953382119	0.176779657	normal	0.036371923	0.422717236	normal	--	--	--	--	--	[S]	Function unknown	PQ loop repeat	PQ-loop repeat-containing protein 1 GN=PQLC1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: PQ-loop repeat-containing protein 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000122507(BBS9)	--	6.775184819	275	3.817956767	238	4.61833627	278	3.77381621	234	5.28435151	322	4.906433365	323	0.924760765	-0.26216534	normal	0.763417782	0.412411999	normal	0.943939942	0.207111707	normal	0.70795795	0.132177967	normal	--	--	--	--	--	[R]	General function prediction only	PTHB1 N-terminus;; PTHB1 C-terminus	Protein PTHB1 GN=BBS9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein PTHB1 isoform X1 [Ursus maritimus] 
ENSG00000122512(PMS2)	--	11.49638282	724	9.971825019	619	11.31655842	689	11.00627719	679	10.29777373	634	10.3420655	657	0.968303906	-0.123140469	normal	0.973466593	0.013085285	normal	0.972471461	-0.076729568	normal	0.822459709	-0.065938708	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	"K10858|0|hsa:5395|PMS2, HNPCC4, PMS2CL, PMSL2; PMS2 postmeiotic segregation increased 2 (S. cerevisiae); K10858 DNA mismatch repair protein PMS2 (A)"	Mismatch repair (ko03430);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	"MutL C terminal dimerisation domain;; DNA mismatch repair protein, C-terminal domain;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	Mismatch repair endonuclease PMS2 GN=PMS2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: mismatch repair endonuclease PMS2 isoform X1 [Tupaia chinensis]
ENSG00000122515(ZMIZ2)	--	19.0200031	1689	15.58638	1493	18.11163354	1695	23.89413495	2090	21.39825926	1868	19.41743305	1813	0.941075793	0.276275085	normal	0.920439447	0.301580143	normal	0.983287596	0.088725656	normal	0.211638714	0.221320929	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[K]	Transcription	MIZ/SP-RING zinc finger;; Zinc-finger of the MIZ type in Nse subunit	Zinc finger MIZ domain-containing protein 2 GN=ZMIZ2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger MIZ domain-containing protein 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000122543(OCM)	--	0.109632	1	0.417636738	3	0	0	0.10379	1	0	0	0.135912769	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand	Oncomodulin-1 GN=OCM OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: oncomodulin-1 [Trichechus manatus latirostris] 
ENSG00000122545(SEPT7)	--	103.1865892	2965	111.7756567	3179	118.947251	3006	120.512736	3519	104.2564416	3081	98.67319272	2806	0.976307149	0.216198217	normal	0.989372874	-0.066568723	normal	0.987362243	-0.107565419	normal	0.954684329	0.017863606	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K16944|0|ssc:100523875|SEPT7; septin 7; K16944 septin 7 (A)	--	[DZU]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	"Septin;; 50S ribosome-binding GTPase;; Protein of unknown function, DUF258"	Septin-7 GN=SEPT7 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: septin-7 isoform X1 [Condylura cristata]
ENSG00000122547(EEPD1)	--	4.064004446	291	3.435272418	309	2.86349098	277	9.918953386	729	10.69433249	804	10.3197098	585	4.11E-10	1.289620901	up	3.75E-11	1.353901961	up	1.82E-06	1.06616211	up	1.15E-09	1.250195867	up	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Biological Process: protein secretion (GO:0009306);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[K]	Transcription	"Helix-hairpin-helix motif;; Helix-hairpin-helix motif;; Type II secretion system (T2SS), protein K;; Helix-hairpin-helix domain;; Helix-hairpin-helix motif;; Helix-hairpin-helix motif;; Endonuclease/Exonuclease/phosphatase family"	Endonuclease/exonuclease/phosphatase family domain-containing protein 1 GN=EEPD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: endonuclease/exonuclease/phosphatase family domain-containing protein 1 isoform 3 [Canis lupus familiaris]
ENSG00000122550(KLHL7)	--	20.18789375	587	15.68696963	487	19.34000169	567	16.90735484	534	17.46250765	509	17.45481192	531	0.957879495	-0.16689478	normal	0.970215771	0.042189177	normal	0.967861643	-0.102645356	normal	0.787087247	-0.081227503	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10445|0|tup:102471641|KLHL7; kelch-like family member 7; K10445 kelch-like protein 7 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 7 GN=KLHL7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 7 [Galeopterus variegatus]
ENSG00000122557(HERPUD2)	--	9.443297303	432	11.06211084	533	9.721159542	472	10.42964172	496	10.4251144	487	12.398939	594	0.955640331	0.167918892	normal	0.959404574	-0.151191345	normal	0.868144321	0.322461738	normal	0.690662532	0.113369182	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin family	Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein GN=HERPUD2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 2 protein [Pantholops hodgsonii]
ENSG00000122565(CBX3)	--	167.5699538	4521	175.514701	4765	165.1053775	4425	185.5288979	5097	166.4173125	4470	155.1761571	4153	0.989704831	0.142128664	normal	0.990632407	-0.113590711	normal	0.99087284	-0.099779819	normal	0.95026735	-0.020982166	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	K11586|2.63678e-86|mdo:100010415|CBX3; chromobox homolog 3; K11586 chromobox protein 3 (A)	--	[B]	Chromatin structure and dynamics	Chromo shadow domain;; Chromo (CHRromatin Organisation MOdifier) domain	Chromobox protein homolog 3 GN=CBX3 OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: chromobox protein homolog 3-like [Bos taurus] 
ENSG00000122566(HNRNPA2B1)	--	500.9331	18317	534.74998	20166	564.92987	20761	584.50915	21517	546.8294	19496	510.59109	18511	0.995027885	0.201445844	normal	0.997554094	-0.070167998	normal	0.995922175	-0.17377113	normal	0.971083755	-0.014740077	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13158|8.9908e-129|mcf:101925647|uncharacterized LOC101925647; K13158 heterogeneous nuclear ribonucleoprotein A2/B1 (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoproteins A2/B1 GN=HNRNPA2B1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoproteins A2/B1 isoform X1 [Equus przewalskii] 
ENSG00000122574(WIPF3)	--	4.054009	310	3.392254	251	2.784172	207	2.289051	174	2.10398	163	1.6578189	131	0.003788455	-0.858251532	normal	0.219438089	-0.63942216	normal	0.238617619	-0.662220318	normal	0.010261781	-0.737056673	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	--	--	[Z]	Cytoskeleton	WH2 motif	WAS/WASL-interacting protein family member 3 GN=WIPF3 OS=Homo sapiens (Human) PE=2 SV=4	Z	Cytoskeleton	PREDICTED: WAS/WASL-interacting protein family member 3 [Equus caballus]
ENSG00000122591(FAM126A)	--	15.67273117	1211	17.97883673	1337	20.13174741	1311	19.61892726	1409	16.60370948	1127	19.4807294	1350	0.966548562	0.187419888	normal	0.934460961	-0.267608353	normal	0.982434142	0.033961673	normal	0.975683854	-0.011331004	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Hyccin	Hyccin GN=FAM126A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: hyccin isoform X1 [Camelus bactrianus] 
ENSG00000122592(HOXA7)	--	2.776052903	99	3.049202432	107	2.7320038	98	3.219852459	114	4.03104	151	5.073563	186	0.962863729	0.170237704	normal	0.805955633	0.469896033	normal	0.014785501	0.905843544	normal	0.120094499	0.549232638	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09307|2.57999e-130|hsa:3204|HOXA7, ANTP, HOX1, HOX1.1, HOX1A; homeobox A7; K09307 homeobox protein HoxA/B7 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-A7 GN=HOXA7 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-A7 [Equus caballus]
ENSG00000122641(INHBA)	--	0.179394292	15	0.204274166	13	0.085688435	5	0.439835682	32	0.286776194	24	0.37880274	24	0.868383627	0.991385975	normal	0.958489153	0.794242362	normal	0.269637172	1.962873105	normal	0.055830038	1.253932391	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04667|0|ptr:463371|INHBA; inhibin, beta A; K04667 inhibin, beta (A)"	TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain;; TGF-beta propeptide	Inhibin beta A chain (Precursor) GN=INHBA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inhibin beta A chain isoform X1 [Tupaia chinensis] 
ENSG00000122642(FKBP9)	--	73.2355173	4879	69.6616428	4738	61.95066454	4172	67.66888672	4546	63.0118958	4166	60.99289974	4066	0.990095777	-0.132776732	normal	0.982525203	-0.206971407	normal	0.991995263	-0.045403713	normal	0.538605332	-0.131642467	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K09575|0|hsa:11328|FKBP9, FKBP60, FKBP63, PPIase; FK506 binding protein 9, 63 kDa (EC:5.2.1.8); K09575 FK506-binding protein 9/10 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; EF hand;; EF-hand domain	Peptidyl-prolyl cis-trans isomerase FKBP9 (Precursor) GN=FKBP9 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP9 isoform X1 [Bubalus bubalis]
ENSG00000122643(NT5C3A)	--	17.484072	429	18.10769371	442	17.42497582	407	25.0426687	586	25.62269088	557	21.73172075	492	0.68198053	0.417806011	normal	0.881680671	0.311253924	normal	0.918573963	0.26444314	normal	0.11410958	0.333581443	normal	--	--	Molecular Function: magnesium ion binding (GO:0000287);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: 5'-nucleotidase activity (GO:0008253);; 	"K01081|0|pps:100982054|NT5C3A, NT5C3; 5'-nucleotidase, cytosolic IIIA; K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	[S]	Function unknown	Pyrimidine 5'-nucleotidase (UMPH-1)	Cytosolic 5'-nucleotidase 3A GN=NT5C3A OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: cytosolic 5'-nucleotidase 3A isoform X1 [Equus caballus] 
ENSG00000122644(ARL4A)	--	24.30288815	698	19.35915099	551	21.82435464	615	22.8443393	649	23.62086182	684	17.45825601	517	0.966019977	-0.135531328	normal	0.90263426	0.289802374	normal	0.923845323	-0.258020652	normal	0.929935575	-0.03261151	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07945|1.21057e-135|ptr:741708|ARL4A; ADP-ribosylation factor-like 4A; K07945 ADP-ribosylation factor-like protein 4 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Miro-like protein;; Signal recognition particle receptor beta subunit;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region	ADP-ribosylation factor-like protein 4A GN=ARL4A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 4A [Echinops telfairi]
ENSG00000122674(CCZ1)	--	8.210090441	269	7.772273969	255	8.129014432	264	10.53700888	347	10.15790819	331	9.86801034	323	0.867162025	0.334809767	normal	0.849759803	0.353065042	normal	0.912099873	0.281245967	normal	0.211781374	0.323788922	normal	--	--	--	--	--	[V]	Defense mechanisms	Fungal domain of unknown function (DUF1712)	Vacuolar fusion protein CCZ1 homolog GN=CCZ1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: vacuolar fusion protein CCZ1 homolog B-like [Chrysochloris asiatica]
ENSG00000122678(POLM)	--	5.77330535	306	5.343112647	278	6.072685067	257	4.401956878	225	5.956803565	288	4.990049174	245	0.627733192	-0.471664854	normal	0.96620042	0.02940024	normal	0.964754866	-0.076815052	normal	0.605720556	-0.170948759	normal	--	--	--	"K03513|0|hsa:27434|POLM, Pol_Mu, Tdt-N; polymerase (DNA directed), mu (EC:2.7.7.7); K03513 DNA polymerase mu [EC:2.7.7.7] (A)"	Non-homologous end-joining (ko03450)	[L]	"Replication, recombination and repair"	Helix-hairpin-helix domain;; DNA polymerase beta thumb	DNA-directed DNA/RNA polymerase mu GN=POLM OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA-directed DNA/RNA polymerase mu isoform X3 [Bison bison bison]
ENSG00000122691(TWIST1)	--	7.018123362	159	7.46698	145	7.786353892	188	6.028066238	149	7.45399	149	7.662741203	167	0.962639958	-0.12331541	normal	0.966579744	0.017651269	normal	0.954464048	-0.177658753	normal	0.835253959	-0.101875451	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09069|2.70927e-73|hsa:7291|TWIST1, ACS3, BPES2, BPES3, CRS, CRS1, CSO, SCS, TWIST, bHLHa38; twist family bHLH transcription factor 1; K09069 twist (A)"	Proteoglycans in cancer (ko05205)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Twist-related protein 1 GN=TWIST1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: twist-related protein 1 [Orcinus orca]
ENSG00000122692(SMU1)	--	12.5245949	1489	12.6241285	1523	12.57453205	1479	13.24317335	1592	13.70312615	1625	12.7190235	1525	0.982972805	0.065598852	normal	0.982558183	0.072027973	normal	0.983697567	0.035859638	normal	0.823635938	0.057128747	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K13111|0|umr:103667029|SMU1; smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans); K13111 WD40 repeat-containing protein SMU1 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Nucleoporin Nup120/160"	"WD40 repeat-containing protein SMU1, N-terminally processed GN=SMU1 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	WD40 repeat-containing protein SMU1 [Bos taurus] 
ENSG00000122694(GLIPR2)	--	4.409307272	140	2.893545391	86	3.662487721	119	9.136350412	294	10.2570377	317	6.200896616	199	0.000166161	1.031577514	up	1.02E-13	1.842600945	up	0.132713233	0.726302241	normal	0.00053606	1.209387469	up	[S]	Function unknown	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family	Golgi-associated plant pathogenesis-related protein 1 GN=GLIPR2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: golgi-associated plant pathogenesis-related protein 1 [Felis catus] 
ENSG00000122696(SLC25A51)	--	8.20556	666	10.66652	713	7.94016	631	10.07053	821	8.72881	780	12.42638	924	0.919364111	0.270464999	normal	0.970400421	0.107926582	normal	0.202803195	0.540883881	normal	0.097290474	0.308051538	normal	--	--	--	--	--	[R]	General function prediction only	Mitochondrial carrier protein	Solute carrier family 25 member 51 GN=SLC25A51 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 51 [Galeopterus variegatus]
ENSG00000122705(CLTA)	--	159.8888163	2905	185.539977	3450	167.1312718	3137	201.748426	3731	197.4962702	3591	213.106588	3935	0.921382632	0.330037576	normal	0.990845724	0.036347117	normal	0.934413083	0.318549272	normal	0.206657924	0.224928778	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: clathrin coat of trans-Golgi network vesicle (GO:0030130);; Cellular Component: clathrin coat of coated pit (GO:0030132);; 	"K04644|1.23002e-147|cfr:102520377|CLTA; clathrin, light chain A; K04644 clathrin light chain A (A)"	Lysosome (ko04142);; Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016);; Bacterial invasion of epithelial cells (ko05100)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin light chain	Clathrin light chain A GN=CLTA OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: clathrin light chain A isoform X1 [Camelus ferus] 
ENSG00000122707(RECK)	--	4.495478137	339	3.236720713	248	4.026407565	297	4.521536	329	4.526891	315	4.689185286	328	0.965962782	-0.073690902	normal	0.883131389	0.321840202	normal	0.959454041	0.134290533	normal	0.736811006	0.115781284	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17461|0|hsa:8434|RECK, ST15; reversion-inducing-cysteine-rich protein with kazal motifs; K17461 reversion-inducing-cysteine-rich protein with kazal motifs (A)"	MicroRNAs in cancer (ko05206)	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Reversion-inducing cysteine-rich protein with Kazal motifs (Precursor) GN=RECK OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: reversion-inducing cysteine-rich protein with Kazal motifs isoform 1 [Orcinus orca]
ENSG00000122711(SPINK4)	--	0	0	0.969746273	2	1.853511011	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Serine protease inhibitor Kazal-type 4 (Precursor) GN=SPINK4 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: serine protease inhibitor Kazal-type 4 [Pteropus alecto]
ENSG00000122729(ACO1)	--	37.1103966	2716	31.42641583	2318	39.60698878	2860	42.2002741	3058	42.8973445	3115	52.8483583	3846	0.985056946	0.140197893	normal	0.785791934	0.404696537	normal	0.75217741	0.41886051	normal	0.112699732	0.323661156	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; 	"K01681|0|hsa:48|ACO1, ACONS, HEL60, IREB1, IREBP, IREBP1, IRP1; aconitase 1, soluble (EC:4.2.1.3); K01681 aconitate hydratase [EC:4.2.1.3] (A)"	Citrate cycle (TCA cycle) (ko00020);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	Aconitase family (aconitate hydratase);; Aconitase C-terminal domain	Cytoplasmic aconitate hydratase GN=ACO1 OS=Homo sapiens (Human) PE=1 SV=3	AJ	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	PREDICTED: cytoplasmic aconitate hydratase [Equus przewalskii] 
ENSG00000122735(DNAI1)	--	0.200966161	4	0.11404027	6	0.113552773	4	0	0	0.033350068	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10409|0|hsa:27019|DNAI1, CILD1, DIC1, ICS1, PCD; dynein, axonemal, intermediate chain 1; K10409 dynein intermediate chain 1, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"WD domain, G-beta repeat"	"Dynein intermediate chain 1, axonemal GN=DNAI1 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: dynein intermediate chain 1, axonemal [Tupaia chinensis]"
ENSG00000122741(DCAF10)	--	8.484052479	827	7.162300893	716	6.870286751	661	9.018018959	892	10.65510883	987	9.398352652	902	0.975264184	0.078184242	normal	0.596354421	0.440867771	normal	0.588303215	0.439321969	normal	0.079962552	0.31413879	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11802|0|ptr:747608|DCAF10, WDR32; DDB1 and CUL4 associated factor 10; K11802 WD repeat-containing protein 32 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 10 GN=DCAF10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 10 [Pteropus alecto]
ENSG00000122756(CNTFR)	--	0	0	0	0	0	0	0	0	0.080941849	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K05059|0|hsa:1271|CNTFR; ciliary neurotrophic factor receptor; K05059 ciliary neurotrophic factor receptor (A)	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	Fibronectin type III domain;; Immunoglobulin domain	Ciliary neurotrophic factor receptor subunit alpha (Precursor) GN=CNTFR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ciliary neurotrophic factor receptor subunit alpha isoform X1 [Galeopterus variegatus]
ENSG00000122778(KIAA1549)	--	9.460578131	1691	8.900017	1550	9.997704	1670	6.5775333	1202	6.713669261	1173	6.6459972	1206	0.242160379	-0.522705647	normal	0.672560841	-0.423015637	normal	0.433295547	-0.477398589	normal	0.001371425	-0.476769364	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF3827)	UPF0606 protein KIAA1549 GN=KIAA1549 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: UPF0606 protein KIAA1549 homolog [Ceratotherium simum simum]
ENSG00000122779(TRIM24)	--	8.413534437	696	8.4139817	669	8.286062354	670	10.6319955	866	12.809159	1042	11.79543413	971	0.910195748	0.28388475	normal	0.057602798	0.616725041	normal	0.246910993	0.52602702	normal	0.003293614	0.47972811	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	K08881|0|pps:100983511|TRIM24; tripartite motif containing 24; K08881 tripartite motif-containing protein 24 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Bromodomain;; B-box zinc finger;; PHD-finger	Transcription intermediary factor 1-alpha GN=TRIM24 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription intermediary factor 1-alpha isoform 1 [Odobenus rosmarus divergens]
ENSG00000122783(C7orf49)	--	34.042765	961	34.92330327	1012	32.08692	914	41.92632	1220	36.6398083	1067	45.119931	1291	0.89096625	0.312995558	normal	0.978426299	0.054844509	normal	0.377518436	0.489247098	normal	0.097071099	0.288355002	normal	--	--	--	--	--	--	--	Modulator of retrovirus infection	Modulator of retrovirus infection homolog GN=MRI OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: modulator of retrovirus infection homolog [Galeopterus variegatus] 
ENSG00000122786(CALD1)	--	47.9296175	4459	53.73470996	4913	53.14512798	4939	80.69419706	6997	73.46709487	6266	67.039448	6066	0.054570156	0.619012454	normal	0.946356289	0.329423991	normal	0.96621457	0.288155341	normal	0.0090415	0.412070787	normal	--	--	--	"K12327|1.97671e-116|hsa:800|CALD1, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22; caldesmon 1; K12327 caldesmon (A)"	Vascular smooth muscle contraction (ko04270)	--	--	Caldesmon	Caldesmon GN=CALD1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: non-muscle caldesmon isoform X4 [Balaenoptera acutorostrata scammoni]
ENSG00000122787(AKR1D1)	--	0.052734353	2	0	0	0	0	0	0	0.050316082	0	0.058416201	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K00251|0|ptr:472607|AKR1D1; aldo-keto reductase family 1, member D1; K00251 3-oxo-5-beta-steroid 4-dehydrogenase [EC:1.3.1.3] (A)"	Primary bile acid biosynthesis (ko00120);; Steroid hormone biosynthesis (ko00140)	[R]	General function prediction only	Aldo/keto reductase family	3-oxo-5-beta-steroid 4-dehydrogenase GN=AKR1D1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: 3-oxo-5-beta-steroid 4-dehydrogenase isoform X1 [Ursus maritimus]
ENSG00000122824(NUDT10)	--	0.38443677	12	0.125465517	4	0.218040966	6	0.06253714	2	0.3378532	10	0.063222684	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K07766|5.27085e-89|nle:100583670|NUDT10; nudix (nucleoside diphosphate linked moiety X)-type motif 10; K07766 diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] (A)	--	[T]	Signal transduction mechanisms	NUDIX domain	Diphosphoinositol polyphosphate phosphohydrolase 3-alpha GN=NUDT10 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: diphosphoinositol polyphosphate phosphohydrolase 3-beta-like [Vicugna pacos] 
ENSG00000122861(PLAU)	--	79.047865	2933	84.56145	3114	98.97726	3459	107.6201	3989	83.67267	2991	105.476846	3883	0.774494627	0.412631813	normal	0.988764176	-0.079528179	normal	0.985994888	0.158459831	normal	0.478847407	0.171342349	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01348|0|ptr:738078|PLAU; plasminogen activator, urokinase; K01348 urokinase plasminogen activator [EC:3.4.21.73] (A)"	NF-kappa B signaling pathway (ko04064);; Complement and coagulation cascades (ko04610);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	--	--	Trypsin;; Kringle domain;; Domain of unknown function (DUF316)	Urokinase-type plasminogen activator chain B (Precursor) GN=PLAU OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: urokinase-type plasminogen activator isoform X1 [Equus caballus] 
ENSG00000122862(SRGN)	--	82.69708	1289	66.40018	1027	77.35883	1192	67.92813	1081	59.58147	926	63.71594	1006	0.920639574	-0.284347311	normal	0.964952701	-0.170514068	normal	0.939382705	-0.252695952	normal	0.185471515	-0.240820009	normal	--	--	--	"K06849|3.73628e-84|hsa:5552|SRGN, PPG, PRG, PRG1; serglycin; K06849 proteoglycan peptide core protein (A)"	--	--	--	Serglycin	Serglycin (Precursor) GN=SRGN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serglycin [Vicugna pacos]
ENSG00000122863(CHST3)	--	9.734470552	1329	9.317822961	1305	10.22802253	1424	24.24357904	3317	22.3494675	3039	19.50468935	2683	1.06E-12	1.287731743	up	1.70E-10	1.197184896	up	8.79E-06	0.904894824	normal	1.22E-17	1.133718388	up	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	K01020|0|ptr:466290|CHST3; carbohydrate (chondroitin 6) sulfotransferase 3; K01020 chondroitin 6-sulfotransferase 3 [EC:2.8.2.17] (A)	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	--	--	Sulfotransferase domain	Carbohydrate sulfotransferase 3 GN=CHST3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: carbohydrate sulfotransferase 3 [Condylura cristata]
ENSG00000122870(BICC1)	--	43.43303443	4474	44.37296054	4547	42.6863264	4339	47.39620736	4829	56.39876889	5755	58.98363188	6080	0.992078205	0.079300728	normal	0.950517738	0.318380055	normal	0.570261331	0.47827583	normal	0.079067946	0.298272712	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	"K18756|0|hsa:80114|BICC1, BICC, CYSRD; BicC family RNA binding protein 1; K18756 protein bicaudal C (A)"	--	--	--	KH domain;; KH domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Protein bicaudal C homolog 1 GN=BICC1 OS=Homo sapiens (Human) PE=1 SV=2	AI	RNA processing and modification;; Lipid transport and metabolism	PREDICTED: protein bicaudal C homolog 1 [Ceratotherium simum simum]
ENSG00000122873(CISD1)	--	11.09827	425	9.33789	363	10.665049	386	13.32378	514	13.64477	511	11.99117	449	0.930363798	0.242674594	normal	0.542573769	0.470268643	normal	0.943711625	0.209063051	normal	0.170782664	0.306741824	normal	--	--	"Cellular Component: intracellular membrane-bounded organelle (GO:0043231);; Molecular Function: 2 iron, 2 sulfur cluster binding (GO:0051537);; "	--	--	[R]	General function prediction only	Iron-binding zinc finger CDGSH type;; Iron-containing outer mitochondrial membrane protein N-terminus	CDGSH iron-sulfur domain-containing protein 1 GN=CISD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: CDGSH iron-sulfur domain-containing protein 1-like [Echinops telfairi]
ENSG00000122877(EGR2)	--	0.020433553	1	0	0	0	0	0.020596522	1	0.059587288	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K12496|0|ggo:101137152|EGR2; E3 SUMO-protein ligase EGR2 isoform 1; K12496 early growth response protein 2 (A)	Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[R]	General function prediction only	"Domain of unknown function (DUF3446);; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	E3 SUMO-protein ligase EGR2 GN=EGR2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: E3 SUMO-protein ligase EGR2 isoform 1 [Ceratotherium simum simum] 
ENSG00000122882(ECD)	--	14.379705	745	17.07131632	900	15.14491423	759	14.044917	728	15.40237644	817	13.29538282	704	0.97425291	-0.064000709	normal	0.964798591	-0.160731874	normal	0.969788724	-0.11657466	normal	0.629022553	-0.117550971	normal	--	--	--	--	--	[K]	Transcription	SGT1 protein;; Putative binding domain	Protein SGT1 GN=ECD OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein SGT1 [Galeopterus variegatus]
ENSG00000122884(P4HA1)	--	33.74656421	1543	36.68141953	1685	33.5675363	1513	38.71751358	1785	20.14879669	917	30.66278835	1403	0.972433099	0.179187757	normal	2.42E-05	-0.898071214	normal	0.978983328	-0.117066876	normal	0.594797871	-0.230226647	normal	--	--	"Molecular Function: procollagen-proline 4-dioxygenase activity (GO:0004656);; Cellular Component: endoplasmic reticulum (GO:0005783);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00472|0|hsa:5033|P4HA1, P4HA; prolyl 4-hydroxylase, alpha polypeptide I (EC:1.14.11.2); K00472 prolyl 4-hydroxylase [EC:1.14.11.2] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	"Prolyl 4-Hydroxylase alpha-subunit, N-terminal region;; 2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily"	Prolyl 4-hydroxylase subunit alpha-1 (Precursor) GN=P4HA1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: prolyl 4-hydroxylase subunit alpha-1 isoform X2 [Ailuropoda melanoleuca]
ENSG00000122912(SLC25A16)	--	11.86902656	904	11.0808626	955	11.91354514	969	11.91327809	1020	12.17923525	1045	11.08173901	986	0.969885524	0.143113137	normal	0.974323248	0.108339705	normal	0.979250785	0.016773587	normal	0.721371218	0.088297526	normal	--	--	--	"K15084|0|hsa:8034|SLC25A16, D10S105E, GDA, GDC, HGT.1, ML7, hML7; solute carrier family 25 (mitochondrial carrier), member 16; K15084 solute carrier family 25 (mitochondrial carrier protein), member 16 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Graves disease carrier protein GN=SLC25A16 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: graves disease carrier protein [Balaenoptera acutorostrata scammoni]
ENSG00000122952(ZWINT)	--	38.45808278	1361	43.28333459	1501	42.63884241	1535	41.76805263	1439	38.83391027	1304	34.25763403	1159	0.982520687	0.049512901	normal	0.95759959	-0.224164118	normal	0.690906147	-0.413179465	normal	0.304117219	-0.194039394	normal	--	--	Cellular Component: kinetochore (GO:0000776);; Biological Process: mitotic cell cycle checkpoint (GO:0007093);; 	--	--	--	--	ZW10 interactor	ZW10 interactor GN=ZWINT OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ZW10 interactor [Ceratotherium simum simum]
ENSG00000122958(VPS26A)	--	40.31297636	1640	45.14924939	1849	40.20335687	1604	42.27728232	1757	40.02389102	1634	47.4461404	1943	0.983911753	0.068524086	normal	0.968907158	-0.199590013	normal	0.944043988	0.268090332	normal	0.865814943	0.045602759	normal	--	--	--	K18466|0|ptr:748846|VPS26A; vacuolar protein sorting 26 homolog A (S. pombe); K18466 vacuolar protein sorting-associated protein 26 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar protein sorting-associated protein 26	Vacuolar protein sorting-associated protein 26A GN=VPS26A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 26A [Ursus maritimus]
ENSG00000122965(RBM19)	--	6.49612392	1002	8.43845339	1268	7.77578708	1237	6.834611	999	6.7733122	1051	8.561711	1352	0.97909826	-0.035104281	normal	0.915571981	-0.291835685	normal	0.9771456	0.119818055	normal	0.865872406	-0.064034235	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K14787|0|hsa:9904|RBM19; RNA binding motif protein 19; K14787 multiple RNA-binding domain-containing protein 1 (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif;; Limkain b1"	Probable RNA-binding protein 19 GN=RBM19 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: probable RNA-binding protein 19 isoform X1 [Equus caballus] 
ENSG00000122966(CIT)	--	10.50994538	1748	10.659644	1757	9.083830842	1699	11.00317319	1778	9.160338269	1528	10.36973607	1748	0.985667975	-0.006276654	normal	0.961538804	-0.222690471	normal	0.985174894	0.032699195	normal	0.799031518	-0.063559992	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16308|0|hsa:11113|CIT, CRIK, STK21; citron rho-interacting serine/threonine kinase (EC:2.7.11.1); K16308 citron Rho-interacting kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	CNH domain;; Protein kinase domain;; Protein tyrosine kinase;; Protein kinase C terminal domain	Citron Rho-interacting kinase GN=CIT OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: citron Rho-interacting kinase [Pteropus alecto]
ENSG00000122970(IFT81)	--	22.477497	1310	24.41692101	1405	24.28805558	1376	18.87992258	1101	17.50781595	1009	18.05786293	1043	0.923544805	-0.281224266	normal	0.3612673	-0.498434297	normal	0.704014136	-0.407516612	normal	0.01173152	-0.397101747	normal	--	--	--	--	--	--	--	--	Intraflagellar transport protein 81 homolog GN=IFT81 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: intraflagellar transport protein 81 homolog isoform 1 [Dasypus novemcinctus] 
ENSG00000122971(ACADS)	--	11.72370385	408	8.070318744	286	8.465322286	303	9.939658839	347	10.69760663	372	8.997115482	315	0.919177047	-0.263388773	normal	0.83950563	0.356205255	normal	0.96705956	0.047510019	normal	0.947264022	0.031001827	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00248|0|hsa:35|ACADS, ACAD3, SCAD; acyl-CoA dehydrogenase, C-2 to C-3 short chain (EC:1.3.8.1); K00248 butyryl-CoA dehydrogenase [EC:1.3.8.1] (A)"	"Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Butanoate metabolism (ko00650);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, middle domain"	"Short-chain specific acyl-CoA dehydrogenase, mitochondrial (Precursor) GN=ACADS OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: short-chain specific acyl-CoA dehydrogenase, mitochondrial [Galeopterus variegatus]"
ENSG00000122986(HVCN1)	--	0.227016	4	0.36273347	9	1.123356	9	0.396365369	9	0.3033337	7	0.162812288	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	--	--	Ion transport protein	Voltage-gated hydrogen channel 1 GN=HVCN1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: voltage-gated hydrogen channel 1 isoform X1 [Physeter catodon]
ENSG00000123064(DDX54)	--	26.70550976	2522	28.57861532	2719	26.55152985	2647	31.62106571	3070	32.824771	3065	28.52311383	2796	0.963248753	0.252698409	normal	0.983838542	0.151305068	normal	0.988381516	0.070675432	normal	0.420255566	0.15772073	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: ATP-dependent RNA helicase activity (GO:0004004);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14808|0|hsa:79039|DDX54, DP97; DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 (EC:3.6.4.13); K14808 ATP-dependent RNA helicase DDX54/DBP10 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; DBP10CT (NUC160) domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	ATP-dependent RNA helicase DDX54 GN=DDX54 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX54 isoform 1 [Ceratotherium simum simum]
ENSG00000123066(MED13L)	--	16.24543335	2976	16.20248725	2985	16.28443276	2873	16.85284127	2785	18.0927023	3155	15.3126296	2905	0.986112083	-0.126461952	normal	0.989426982	0.058453709	normal	0.989935072	0.007684706	normal	0.951471013	-0.019278549	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	"K15164|0|hsa:23389|MED13L, PROSIT240, THRAP2, TRAP240L; mediator complex subunit 13-like; K15164 mediator of RNA polymerase II transcription subunit 13 (A)"	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	Mediator complex subunit 13 C-terminal;; Mediator complex subunit 13 N-terminal	Mediator of RNA polymerase II transcription subunit 13-like GN=MED13L OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 13-like [Ceratotherium simum simum]
ENSG00000123080(CDKN2C)	--	3.894691171	147	5.055678279	195	4.196938598	168	7.2574961	275	10.2109888	373	8.109892	292	0.005797416	0.86606537	normal	0.000862629	0.909092668	normal	0.019262063	0.783797947	normal	0.000272472	0.861196008	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K06622|8.26438e-107|ptr:469319|CDKN2C; cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4); K06622 cyclin-dependent kinase inhibitor 2C (A)"	Cell cycle (ko04110);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Domain of unknown function (DUF1843)	Cyclin-dependent kinase 4 inhibitor C GN=CDKN2C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-dependent kinase 4 inhibitor C [Galeopterus variegatus] 
ENSG00000123091(RNF11)	--	19.97614517	902	18.7823863	821	20.17043114	854	21.84018395	965	21.06089836	933	17.96345	790	0.977005218	0.066459791	normal	0.964720745	0.162786878	normal	0.970875423	-0.120453022	normal	0.895315041	0.039094133	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K11980|3.07502e-91|umr:103670730|RNF11; ring finger protein 11; K11980 E3 ubiquitin-protein ligase RNF11 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 11 GN=RNF11 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 11 [Ceratotherium simum simum]
ENSG00000123094(RASSF8)	--	6.181574742	576	7.94517737	593	6.72863426	513	5.347934636	506	5.672891163	526	6.563841236	577	0.942683161	-0.217145139	normal	0.950524929	-0.193870522	normal	0.958999111	0.160873651	normal	0.772792354	-0.085042461	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	K09855|0|mcc:708284|RASSF8; Ras association (RalGDS/AF-6) domain family (N-terminal) member 8; K09855 Ras association domain-containing protein 7/8 (A)	--	[W]	Extracellular structures	Ras association (RalGDS/AF-6) domain	Ras association domain-containing protein 8 GN=RASSF8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ras association domain-containing protein 8 isoform 1 [Canis lupus familiaris] 
ENSG00000123095(BHLHE41)	--	1.37971	87	0.866946	55	0.958628	61	0.562343	36	0.518085	33	0.545671	35	0.008960983	-1.2679125	down	0.826722717	-0.732124929	normal	0.740026548	-0.783777168	normal	0.034988886	-0.986370014	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K03730|3.71264e-160|ptr:465351|BHLHE41, BHLHB3; basic helix-loop-helix family, member e41; K03730 class B basic helix-loop-helix protein 3 (A)"	Circadian rhythm (ko04710)	[K]	Transcription	Helix-loop-helix DNA-binding domain;; Hairy Orange	Class E basic helix-loop-helix protein 41 GN=BHLHE41 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: class E basic helix-loop-helix protein 41, partial [Camelus bactrianus]"
ENSG00000123096(SSPN)	--	0.733762467	47	1.482023916	52	0.98991595	51	0.466937998	17	0.741398277	36	0.934297876	30	0.105715676	-1.417769144	normal	0.932410178	-0.533198869	normal	0.849084218	-0.744713643	normal	0.10683117	-0.873271489	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	CD20-like family	Sarcospan GN=SSPN OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: sarcospan [Lipotes vexillifer]
ENSG00000123104(ITPR2)	--	2.786388	662	2.155704	512	2.29587	554	2.561537	614	3.22527	757	2.992571	714	0.964759453	-0.139089511	normal	0.236815438	0.541400103	normal	0.816830853	0.356886325	normal	0.230221549	0.25021788	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: calcium channel activity (GO:0005262);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04959|0|hsa:3709|ITPR2, CFAP48, IP3R2; inositol 1,4,5-trisphosphate receptor, type 2; K04959 inositol 1,4,5-triphosphate receptor type 2 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	"RIH domain;; Inositol 1,4,5-trisphosphate/ryanodine receptor;; MIR domain;; RyR and IP3R Homology associated;; Ion transport protein"	"Inositol 1,4,5-trisphosphate receptor type 2 GN=ITPR2 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: inositol 1,4,5-trisphosphate receptor type 2 [Orycteropus afer afer]"
ENSG00000123106(CCDC91)	--	16.4189771	580	14.64324204	656	15.35209408	629	14.28453241	631	18.03086931	663	14.46088542	645	0.970006968	0.090524902	normal	0.974120394	-0.006099516	normal	0.97409247	0.027881502	normal	0.914275011	0.035044044	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000123119(NECAB1)	--	0.571367	36	0.419056	26	0.35858008	21	0.373843	24	0.395118	25	0.2948902	21	0.956395602	-0.585007591	normal	0.985491421	-0.073641546	normal	0.98834667	-0.007734457	normal	0.774678062	-0.267851424	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	Antibiotic biosynthesis monooxygenase;; EF-hand domain pair;; EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand	N-terminal EF-hand calcium-binding protein 1 GN=NECAB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: N-terminal EF-hand calcium-binding protein 1 [Orycteropus afer afer]
ENSG00000123124(WWP1)	--	19.15921359	1290	17.600241	1196	17.94635941	1198	15.95995	1158	17.23384197	1200	15.062321	1023	0.965612956	-0.186333682	normal	0.981091274	-0.016588601	normal	0.947782561	-0.235790745	normal	0.490363783	-0.145374818	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	"K05633|0|hsa:11059|WWP1, AIP5, Tiul1, hSDRP1; WW domain containing E3 ubiquitin protein ligase 1; K05633 atrophin-1 interacting protein 5 (WW domain containing E3 ubiquitin protein ligase 1) [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain;; C2 domain	NEDD4-like E3 ubiquitin-protein ligase WWP1 GN=WWP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1 [Canis lupus familiaris]
ENSG00000123130(ACOT9)	--	36.61479633	1590	36.75974777	1501	33.18209696	1418	42.53571464	1829	41.20264033	1773	34.75869445	1465	0.974317854	0.171041857	normal	0.962672519	0.21863913	normal	0.983192611	0.038711071	normal	0.46834268	0.146378863	normal	[I]	Lipid transport and metabolism	--	K17361|0|mcf:102145163|ACOT9; acyl-CoA thioesterase 9; K17361 acyl-coenzyme A thioesterase 9 [EC:3.1.2.-] (A)	--	[I]	Lipid transport and metabolism	Thioesterase superfamily	"Acyl-coenzyme A thioesterase 9, mitochondrial (Precursor) GN=ACOT9 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: acyl-coenzyme A thioesterase 9, mitochondrial isoform X3 [Tupaia chinensis]"
ENSG00000123131(PRDX4)	--	152.1372307	2094	146.8006295	2078	144.3058492	2028	156.9491581	2270	149.3724356	2064	150.1948984	2105	0.985736019	0.085538305	normal	0.986611754	-0.03115649	normal	0.986653541	0.04543788	normal	0.903207025	0.033071711	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: peroxiredoxin activity (GO:0051920);; Biological Process: oxidation-reduction process (GO:0055114);; 	K03386|8.30661e-179|pps:100991501|PRDX4; peroxiredoxin 4; K03386 peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	AhpC/TSA family;; C-terminal domain of 1-Cys peroxiredoxin;; Redoxin	Peroxiredoxin-4 (Precursor) GN=PRDX4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxiredoxin-4 [Odobenus rosmarus divergens]
ENSG00000123136(DDX39A)	--	45.98877175	1246	57.870418	1622	50.869309	1415	54.690725	1515	52.63952448	1465	56.954322	1548	0.945872534	0.25090054	normal	0.972992248	-0.168134675	normal	0.9787937	0.121188109	normal	0.817737445	0.059033497	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K13182|0|pps:100973226|DDX39A; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; K13182 ATP-dependent RNA helicase DDX39 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	ATP-dependent RNA helicase DDX39A GN=DDX39A OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX39A isoform X1 [Canis lupus familiaris] 
ENSG00000123143(PKN1)	--	54.00467851	3423	51.19394583	3341	52.38882876	3471	56.0728015	3578	57.46431398	3621	58.42841538	3758	0.991122172	0.033045324	normal	0.989260244	0.094640481	normal	0.989308063	0.106277748	normal	0.746712904	0.077353081	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; 	K06071|0|pps:100972885|PKN1; protein kinase N1; K06071 protein kinase N [EC:2.7.11.13] (A)	PI3K-Akt signaling pathway (ko04151);; Salmonella infection (ko05132)	[T]	Signal transduction mechanisms	Protein kinase domain;; Hr1 repeat;; Protein tyrosine kinase;; Protein kinase C terminal domain	Serine/threonine-protein kinase N1 GN=PKN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase N1 [Bison bison bison]
ENSG00000123144(C19orf43)	--	102.449404	1709	101.100653	1800	100.394523	1792	103.005115	1788	101.4745416	1704	107.1053327	1833	0.985262273	0.0343319	normal	0.982188221	-0.100411408	normal	0.985803912	0.024324409	normal	0.965157644	-0.014592812	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C19orf43 GN=C19orf43 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C19orf43 homolog [Condylura cristata]
ENSG00000123146(ADGRE5)	--	26.574064	1430	21.3139923	1205	24.940717	1433	27.3020172	1626	25.98924	1390	24.78788204	1479	0.975197723	0.154324281	normal	0.966909677	0.184409553	normal	0.983335074	0.037253301	normal	0.567889105	0.122650344	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08446|0|ptr:455780|CD97; CD97 molecule; K08446 CD97 antigen (A)	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Latrophilin/CL-1-like GPS domain;; EGF domain;; MSP1 EGF domain 1;; EGF-like domain	CD97 antigen subunit beta (Precursor) GN=CD97 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: CD97 antigen [Galeopterus variegatus]
ENSG00000123154(WDR83)	--	4.64653	119	4.06269	108	3.87023	102	5.54057	144	5.36706	136	5.16015	132	0.947655544	0.241437973	normal	0.92982791	0.30730698	normal	0.913065912	0.35898657	normal	0.476322227	0.30293132	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K13124|0|hsa:84292|WDR83, MORG1; WD repeat domain 83; K13124 mitogen-activated protein kinase organizer 1 (A)"	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat domain-containing protein 83 GN=WDR83 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat domain-containing protein 83 [Vicugna pacos]
ENSG00000123159(GIPC1)	--	84.5058777	2787	85.80271959	2994	75.9280815	2743	84.93596986	2900	88.45171952	2981	89.77777911	3098	0.989689806	0.026493316	normal	0.989761258	-0.027690387	normal	0.982494272	0.16720429	normal	0.833604957	0.053930558	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PDZ domain (Also known as DHR or GLGF)	PDZ domain-containing protein GIPC1 GN=GIPC1 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PDZ domain-containing protein GIPC1 isoform X1 [Pteropus alecto] 
ENSG00000123178(SPRYD7)	--	12.214505	382	11.66364525	399	13.19970633	361	10.745494	330	9.969052735	310	8.973568782	300	0.930831602	-0.240895248	normal	0.792290641	-0.383891529	normal	0.914439496	-0.274066452	normal	0.225872365	-0.302463134	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	SPRY domain	SPRY domain-containing protein 7 GN=SPRYD7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: SPRY domain-containing protein 7 isoform X1 [Elephantulus edwardii]
ENSG00000123179(EBPL)	--	55.641839	587	50.7648321	554	58.38569113	630	61.626198	665	57.108308	607	52.030818	545	0.962847606	0.148795512	normal	0.966950774	0.110096803	normal	0.944029363	-0.216826914	normal	0.969997059	0.015397889	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sterol metabolic process (GO:0016125);; Molecular Function: cholestenol delta-isomerase activity (GO:0047750);; 	--	--	[I]	Lipid transport and metabolism	Emopamil binding protein	Emopamil-binding protein-like GN=EBPL OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	"PREDICTED: emopamil-binding protein-like, partial [Ceratotherium simum simum]"
ENSG00000123191(ATP7B)	--	3.046077336	408	2.298840615	294	2.905653278	391	2.452718299	312	2.805539542	380	2.016945116	270	0.719690399	-0.416057543	normal	0.849731219	0.347182134	normal	0.34619859	-0.539972705	normal	0.549200833	-0.205369086	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion binding (GO:0046872);; 	"K17686|0|hsa:540|ATP7B, PWD, WC1, WD, WND; ATPase, Cu++ transporting, beta polypeptide (EC:3.6.3.54); K17686 Cu+-exporting ATPase [EC:3.6.3.54] (A)"	--	[P]	Inorganic ion transport and metabolism	Heavy-metal-associated domain;; haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase	WND/140 kDa GN=ATP7B OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: copper-transporting ATPase 2 isoform X1 [Galeopterus variegatus]
ENSG00000123200(ZC3H13)	--	8.654918485	1509	9.21715152	1593	8.827774629	1713	8.239547284	1642	8.352451408	1660	7.715741335	1500	0.98189597	0.090940281	normal	0.984078824	0.037975101	normal	0.967510832	-0.199665572	normal	0.933049112	-0.025158717	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[K]	Transcription	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 13 GN=ZC3H13 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger CCCH domain-containing protein 13 isoform X3 [Physeter catodon]
ENSG00000123213(NLN)	--	34.1961519	2597	34.6909731	2649	37.25471265	2812	33.19459047	2467	31.78011592	2381	26.98666867	2096	0.986206936	-0.104856901	normal	0.979311595	-0.175201219	normal	0.672106201	-0.431979226	normal	0.173903194	-0.236185987	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K01393|0|hsa:57486|NLN, AGTBP, EP24.16, MEP, MOP; neurolysin (metallopeptidase M3 family) (EC:3.4.24.16); K01393 neurolysin [EC:3.4.24.16] (A)"	Renin-angiotensin system (ko04614)	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M3	"Neurolysin, mitochondrial (Precursor) GN=NLN OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: neurolysin, mitochondrial isoform X1 [Panthera tigris altaica]"
ENSG00000123219(CENPK)	--	31.65865099	689	30.63798192	670	38.50543239	816	28.30018931	647	23.12963807	519	24.5669418	554	0.967910194	-0.121291345	normal	0.757083097	-0.388852882	normal	0.145517237	-0.565694078	normal	0.05326573	-0.360015418	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K11503|0|hsa:64105|CENPK, AF5alpha, CENP-K, P33, Solt; centromere protein K; K11503 centromere protein K (A)"	--	--	--	Centromere-associated protein K	Centromere protein K GN=CENPK OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein K isoform X1 [Sus scrofa] 
ENSG00000123240(OPTN)	--	19.88953231	1401	20.97871116	1527	20.64321976	1532	24.80373284	1777	22.9085558	1657	34.38057745	2522	0.906380864	0.311850212	normal	0.981316706	0.096355361	normal	0.003746526	0.710308515	normal	0.239652757	0.39720231	normal	--	--	--	--	--	--	--	NF-kappa-B essential modulator NEMO	Optineurin GN=OPTN OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: optineurin [Orycteropus afer afer]
ENSG00000123243(ITIH5)	--	0.035154754	4	0.048509424	3	0.015890704	0	0.208132564	19	0.4829725	43	0.232686008	25	--	--	--	2.52E-06	3.284804308	up	0.000176507	4.127952516	up	--	--	--	[R]	General function prediction only	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Biological Process: hyaluronan metabolic process (GO:0030212);; 	--	--	--	--	Inter-alpha-trypsin inhibitor heavy chain C-terminus;; Vault protein inter-alpha-trypsin domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Inter-alpha-trypsin inhibitor heavy chain H5 (Precursor) GN=ITIH5 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: inter-alpha-trypsin inhibitor heavy chain H5 [Oryctolagus cuniculus]
ENSG00000123268(ATF1)	--	12.85154817	399	12.35898307	386	10.50491802	319	12.52336397	390	15.16614466	446	14.23109198	453	0.967758811	-0.063499549	normal	0.949634256	0.186336691	normal	0.463489995	0.495681542	normal	0.446336076	0.202453862	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09053|2.55001e-161|hsa:466|ATF1, EWS-ATF1, FUS/ATF-1, TREB36; activating transcription factor 1; K09053 activating transcription factor 1 (A)"	HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	bZIP transcription factor;; pKID domain;; Basic region leucine zipper;; bZIP Maf transcription factor	Cyclic AMP-dependent transcription factor ATF-1 GN=ATF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cyclic AMP-dependent transcription factor ATF-1 isoform X3 [Felis catus]
ENSG00000123297(TSFM)	--	25.1819871	841	25.9015602	872	30.14647494	886	27.68867444	926	28.4673927	918	26.53517681	854	0.973122129	0.107886256	normal	0.97668052	0.052650465	normal	0.976509661	-0.061255567	normal	0.912853108	0.032573429	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation elongation factor activity (GO:0003746);; Cellular Component: intracellular (GO:0005622);; Biological Process: translational elongation (GO:0006414);; 	"K02357|0|mcf:102119716|TSFM; Ts translation elongation factor, mitochondrial; K02357 elongation factor Ts (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor TS;; UBA/TS-N domain	"Elongation factor Ts, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03135} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: elongation factor Ts, mitochondrial isoform X2 [Lipotes vexillifer]"
ENSG00000123329(ARHGAP9)	--	0	0	0.0694943	1	0	0	0.0171738	1	0	0	0.124871	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; PH domain;; SH3 domain	Rho GTPase-activating protein 9 GN=ARHGAP9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 9 isoform 1 [Ceratotherium simum simum]
ENSG00000123338(NCKAP1L)	--	0	0	0.014433833	1	0	0	0.014522735	1	0	0	0.028827242	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05750|0|pps:100996138|NCKAP1L; NCK-associated protein 1-like; K05750 NCK-associated protein 1 (A)	Regulation of actin cytoskeleton (ko04810)	[R]	General function prediction only	Membrane-associated apoptosis protein	Nck-associated protein 1-like GN=NCKAP1L OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: nck-associated protein 1-like [Galeopterus variegatus]
ENSG00000123342(MMP19)	--	0.078349945	3	0.0478582	2	0.117183326	4	0.14352083	6	0.22452393	7	0.126600653	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	K07998|0|ggo:101128303|MMP19; matrix metalloproteinase-19; K07998 matrix metalloproteinase-19 (RASI) [EC:3.4.24.-] (A)	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	Matrix metalloproteinase-19 (Precursor) GN=MMP19 OS=Homo sapiens (Human) PE=1 SV=1	OW	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	PREDICTED: matrix metalloproteinase-19 [Galeopterus variegatus]
ENSG00000123349(PFDN5)	--	246.67943	1657	232.656882	1599	234.87481	1618	300.481757	2162	312.3125	2081	270.2699601	1867	0.861741783	0.352673667	normal	0.855961146	0.358382599	normal	0.969386726	0.198046421	normal	0.060499266	0.304451649	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K04797|3.38925e-97|tup:102471709|PFDN5; prefoldin subunit 5; K04797 prefoldin alpha subunit (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prefoldin subunit	Prefoldin subunit 5 GN=PFDN5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prefoldin subunit 5 [Tupaia chinensis]
ENSG00000123352(SPATS2)	--	30.76179102	1788	28.3883749	1644	34.763412	1885	26.96349113	1440	25.84259866	1417	18.3957263	1090	0.868109139	-0.342781204	normal	0.955523971	-0.235563442	normal	0.000339657	-0.7976755	normal	0.002556021	-0.451608348	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1387)	Spermatogenesis-associated serine-rich protein 2 GN=SPATS2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: spermatogenesis-associated serine-rich protein 2 [Ceratotherium simum simum]
ENSG00000123353(ORMDL2)	--	37.25379	550	45.89275	653	34.765415	532	48.244909	631	48.0956	617	41.88058	622	0.958485678	0.166940501	normal	0.968834707	-0.102993631	normal	0.943874757	0.216626857	normal	0.758998567	0.086613914	normal	[S]	Function unknown	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	ORMDL family	ORM1-like protein 2 GN=ORMDL2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: ORM1-like protein 2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000123358(NR4A1)	--	9.546585669	386	18.72111799	791	11.6523399	486	2.718120507	117	4.163743813	181	11.48448424	465	3.92E-14	-1.739572341	down	0	-2.139757041	down	0.969002285	-0.071788644	normal	0.171273182	-1.141741821	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K04465|0|mcc:696797|NR4A1; nuclear receptor subfamily 4, group A, member 1; K04465 nuclear receptor subfamily 4 group A member 1 (A)"	MAPK signaling pathway (ko04010);; PI3K-Akt signaling pathway (ko04151)	[K]	Transcription	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor subfamily 4 group A member 1 GN=NR4A1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	nuclear receptor subfamily 4 group A member 1 [Canis lupus familiaris] 
ENSG00000123360(PDE1B)	--	0	0	0	0	0.060879592	2	0	0	0	0	0.016074364	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13755|0|hsa:5153|PDE1B, PDE1B1, PDES1B; phosphodiesterase 1B, calmodulin-dependent (EC:3.1.4.17); K13755 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17] (A)"	Purine metabolism (ko00230);; Calcium signaling pathway (ko04020);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; 3'5'-cyclic nucleotide phosphodiesterase N-terminal	"Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B GN=PDE1B OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B isoform 1 [Ceratotherium simum simum]"
ENSG00000123364(HOXC13)	--	3.79637	156	4.15118	173	3.11351	131	3.224	132	3.66118	151	3.40865	142	0.937713318	-0.268956573	normal	0.946925707	-0.215630628	normal	0.964892563	0.106847678	normal	0.77952704	-0.135504946	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09298|1.63767e-174|ptr:467008|HOXC13; homeobox C13; K09298 homeobox protein HoxA/C/D13 (A)	--	[K]	Transcription	Homeobox domain;; Hox protein A13 N terminal	Homeobox protein Hox-C13 GN=HOXC13 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-C13 [Galeopterus variegatus]
ENSG00000123374(CDK2)	--	32.33607101	1201	29.76326751	1081	35.60793327	1326	34.1461282	1214	28.86668296	1041	25.17870432	838	0.981619108	-0.01528055	normal	0.977634325	-0.075715064	normal	0.013267724	-0.669381119	normal	0.321035742	-0.244188333	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02206|0|mcf:102139233|CDK2; cyclin-dependent kinase 2; K02206 cyclin-dependent kinase 2 [EC:2.7.11.22] (A)	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Oocyte meiosis (ko04114);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Progesterone-mediated oocyte maturation (ko04914);; Hepatitis B (ko05161);; Measles (ko05162);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215);; Small cell lung cancer (ko05222)	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 2 GN=CDK2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 2 isoform X1 [Galeopterus variegatus]
ENSG00000123384(LRP1)	--	27.9522646	9487	19.354761	6268	25.1726856	8754	23.1367804	7858	22.5513	7679	16.563143	5625	0.971513863	-0.302568104	normal	0.976901186	0.271427459	normal	0.031003076	-0.646240291	normal	0.544984325	-0.233646868	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	"K04550|0|hsa:4035|LRP1, A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5; low density lipoprotein receptor-related protein 1; K04550 low-density lipoprotein receptor-related protein 1 (alpha-2-macroglobulin receptor) (A)"	Alzheimer's disease (ko05010);; Malaria (ko05144)	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; SMP-30/Gluconolaconase/LRE-like region;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; NHL repeat	Low-density lipoprotein receptor-related protein 1 intracellular domain (Precursor) GN=LRP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: prolow-density lipoprotein receptor-related protein 1 [Felis catus]
ENSG00000123388(HOXC11)	--	0.157130996	6	0.03759447	2	0.092629177	4	0.243398649	12	0.267476286	10	0.601980087	24	--	--	--	--	--	--	0.126532693	2.203561095	normal	--	--	--	--	--	--	K09296|0|ptr:451946|HOXC11; homeobox C11; K09296 homeobox protein HoxA/C/D11 (A)	--	[K]	Transcription	Protein of unknown function (DUF3528)	Homeobox protein Hox-C11 GN=HOXC11 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox protein Hox-C11 isoform X1 [Bos taurus]
ENSG00000123395(ATG101)	--	41.77321814	1006	41.48690762	1048	43.10942028	1118	45.85381534	1053	42.094817	976	45.14548715	1068	0.979430754	0.034990634	normal	0.972840153	-0.123926862	normal	0.978589977	-0.074197285	normal	0.835971011	-0.055556604	normal	--	--	Biological Process: autophagy (GO:0006914);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1649)	Autophagy-related protein 101 GN=ATG101 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: autophagy-related protein 101 isoform X1 [Ursus maritimus]
ENSG00000123405(NFE2)	--	0.301179741	10	0	0	0.096941877	1	0.400217495	14	0.690578342	19	0.329679304	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09039|0|hsa:4778|NFE2, NF-E2, p45; nuclear factor, erythroid 2; K09039 nuclear factor erythroid 2 (A)"	--	[K]	Transcription	bZIP Maf transcription factor;; bZIP transcription factor;; Basic region leucine zipper	Transcription factor NF-E2 45 kDa subunit GN=NFE2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor NF-E2 45 kDa subunit isoform 1 [Ceratotherium simum simum] 
ENSG00000123411(IKZF4)	--	1.787082922	139	2.247090783	137	1.5513247	136	1.223555344	110	1.761072643	150	1.795323431	163	0.905872311	-0.363880397	normal	0.963019431	0.108218173	normal	0.941848705	0.250427064	normal	0.985435375	0.018001439	normal	[R]	General function prediction only	--	"K09220|0|ptr:451979|IKZF4, ZNFN1A4; IKAROS family zinc finger 4 (Eos); K09220 IKAROS family zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein Eos GN=IKZF4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein Eos isoform X2 [Galeopterus variegatus]
ENSG00000123415(SMUG1)	--	18.988998	293	15.89773095	345	24.04840674	373	16.01461876	324	18.90302887	324	20.45571031	367	0.961949965	0.113693804	normal	0.961663244	-0.111524539	normal	0.96875055	-0.031558017	normal	0.977026003	-0.014876773	normal	--	--	--	K10800|1.6914e-160|ptr:451953|SMUG1; single-strand-selective monofunctional uracil-DNA glycosylase 1; K10800 single-strand selective monofunctional uracil DNA glycosylase [EC:3.2.2.-] (A)	Base excision repair (ko03410)	--	--	Uracil DNA glycosylase superfamily	Single-strand selective monofunctional uracil DNA glycosylase GN=SMUG1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: single-strand selective monofunctional uracil DNA glycosylase isoform X1 [Equus caballus] 
ENSG00000123416(TUBA1B)	--	803.0269303	22674	845.2822875	23505	953.3373461	26867	1193.813479	33855	977.3787415	27244	829.5549183	23487	0.51403209	0.54746719	normal	0.996149422	0.191532845	normal	0.995837023	-0.202252044	normal	0.510927743	0.189550337	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07374|0|xtr:100038108|tuba4a, tuba1; tubulin, alpha 4a; K07374 tubulin alpha (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha-1B chain GN=TUBA1B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	Tubulin alpha-1D chain [Myotis brandtii]
ENSG00000123444(KBTBD4)	--	13.864045	591	12.7572241	537	13.7576079	549	11.27204	487	11.5266784	492	13.38811	560	0.882233412	-0.30918149	normal	0.960212849	-0.147256902	normal	0.972730519	0.02027394	normal	0.576321601	-0.144697587	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10472|0|pon:100173921|KBTBD4; kelch repeat and BTB (POZ) domain containing 4; K10472 kelch repeat and BTB domain-containing protein 4 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"BTB/POZ domain;; Kelch motif;; BTB And C-terminal Kelch;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain"	Kelch repeat and BTB domain-containing protein 4 GN=KBTBD4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: kelch repeat and BTB domain-containing protein 4 isoform X1 [Mustela putorius furo] 
ENSG00000123453(SARDH)	--	0.087393812	5	0.052188892	2	0.145614641	4	0.053783364	2	0.041248109	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00314|0|hsa:1757|SARDH, BPR-2, DMGDHL1, SAR, SARD, SDH; sarcosine dehydrogenase (EC:1.5.8.3); K00314 sarcosine dehydrogenase [EC:1.5.8.3] (A)"	"Glycine, serine and threonine metabolism (ko00260)"	[E]	Amino acid transport and metabolism	"FAD dependent oxidoreductase;; Aminomethyltransferase folate-binding domain;; Glycine cleavage T-protein C-terminal barrel domain;; Sarcosine oxidase, gamma subunit family"	"Sarcosine dehydrogenase, mitochondrial (Precursor) GN=SARDH OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: sarcosine dehydrogenase, mitochondrial isoform 2 [Ceratotherium simum simum]"
ENSG00000123454(DBH)	--	0.019608662	1	0.019455097	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: monooxygenase activity (GO:0004497);; Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen (GO:0016715);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00503|0|hsa:1621|DBH, DBM; dopamine beta-hydroxylase (dopamine beta-monooxygenase) (EC:1.14.17.1); K00503 dopamine beta-monooxygenase [EC:1.14.17.1] (A)"	Tyrosine metabolism (ko00350)	[E]	Amino acid transport and metabolism	"Copper type II ascorbate-dependent monooxygenase, C-terminal domain;; Copper type II ascorbate-dependent monooxygenase, N-terminal domain;; DOMON domain"	Soluble dopamine beta-hydroxylase GN=DBH OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: dopamine beta-hydroxylase [Galeopterus variegatus]
ENSG00000123472(ATPAF1)	--	19.41486928	748	18.62802116	755	19.45060749	755	21.390011	874	23.9582396	962	21.16920562	844	0.956462156	0.193394985	normal	0.869303397	0.327551221	normal	0.965784601	0.152186466	normal	0.251337541	0.225964088	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; Biological Process: protein complex assembly (GO:0006461);; 	K07555|0|ptr:456558|ATPAF1; ATP synthase mitochondrial F1 complex assembly factor 1; K07555 ATP synthase mitochondrial F1 complex assembly factor 1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATP11 protein	ATP synthase mitochondrial F1 complex assembly factor 1 (Precursor) GN=ATPAF1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: ATP synthase mitochondrial F1 complex assembly factor 1, partial [Camelus bactrianus]"
ENSG00000123473(STIL)	--	7.795452892	685	7.76872397	612	9.599542667	751	8.255196108	727	7.441341151	704	8.595321994	743	0.974209245	0.05489958	normal	0.956425166	0.180201784	normal	0.976008962	-0.02369417	normal	0.822776504	0.065289005	normal	--	--	--	"K16724|0|hsa:6491|STIL, MCPH7, SIL; SCL/TAL1 interrupting locus; K16724 SCL-interrupting locus protein (A)"	--	--	--	SCL-interrupting locus protein N-terminus	SCL-interrupting locus protein GN=STIL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SCL-interrupting locus protein isoform X1 [Equus przewalskii] 
ENSG00000123485(HJURP)	--	37.60449303	2313	30.85525088	1889	35.46650844	2156	29.77481153	1828	30.51399541	1871	26.69906228	1641	0.834862415	-0.370054203	normal	0.985613223	-0.035211376	normal	0.75067288	-0.401749332	normal	0.10271088	-0.273112271	normal	--	--	Cellular Component: nucleus (GO:0005634);; Molecular Function: histone binding (GO:0042393);; 	--	--	--	--	Holliday junction recognition protein-associated repeat;; Holliday junction regulator protein family C-terminal repeat;; Centromere protein Scm3	Holliday junction recognition protein OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Holliday junction recognition protein [Galeopterus variegatus]
ENSG00000123500(COL10A1)	--	0.104375714	7	0.04410298	3	0.029152564	1	0.074481495	5	0.160847864	5	0.059076927	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Collagen triple helix repeat (20 copies);; C1q domain	Collagen alpha-1(X) chain (Precursor) GN=COL10A1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(X) chain [Loxodonta africana]
ENSG00000123505(AMD1)	--	46.81362316	2422	39.1966495	2011	46.02073448	2327	49.1319512	2548	55.74225617	2866	44.76030711	2313	0.98835839	0.042307982	normal	0.444074976	0.489389218	normal	0.988129368	-0.016986314	normal	0.367309156	0.171631988	normal	--	--	Molecular Function: adenosylmethionine decarboxylase activity (GO:0004014);; Biological Process: spermine biosynthetic process (GO:0006597);; Biological Process: spermidine biosynthetic process (GO:0008295);; 	K01611|0|ptr:472092|AMD1; adenosylmethionine decarboxylase 1; K01611 S-adenosylmethionine decarboxylase [EC:4.1.1.50] (A)	Cysteine and methionine metabolism (ko00270);; Arginine and proline metabolism (ko00330)	[T]	Signal transduction mechanisms	Adenosylmethionine decarboxylase	S-adenosylmethionine decarboxylase beta chain (Precursor) GN=AMD1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: S-adenosylmethionine decarboxylase proenzyme [Pteropus alecto] 
ENSG00000123545(NDUFAF4)	--	6.71212	252	5.14249	193	5.4867	202	6.35956	241	6.4708	241	5.3307	200	0.963341996	-0.094632768	normal	0.910118576	0.29692009	normal	0.966820515	-0.022477614	normal	0.907081753	0.054202493	normal	--	--	Biological Process: mitochondrial respiratory chain complex I assembly (GO:0032981);; 	"K18161|4.35676e-125|pps:100993519|NDUFAF4; NADH dehydrogenase (ubiquinone) complex I, assembly factor 4; K18161 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 (A)"	--	[S]	Function unknown	Uncharacterised protein family (UPF0240)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 GN=NDUFAF4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 [Ceratotherium simum simum]
ENSG00000123552(USP45)	--	3.1747976	206	3.0841236	181	3.839876344	210	3.205734836	223	3.548620899	208	3.469379386	200	0.964266925	0.082972257	normal	0.952156355	0.177780799	normal	0.964659723	-0.078104353	normal	0.903207025	0.058556823	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11844|0|hsa:85015|USP45; ubiquitin specific peptidase 45 (EC:3.4.19.12); K11844 ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 45 GN=USP45 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 45 [Orcinus orca]
ENSG00000123561(SERPINA7)	--	0	0	0	0	0	0	0	0	0	0	0.036469229	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Thyroxine-binding globulin (Precursor) GN=SERPINA7 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: thyroxine-binding globulin [Ursus maritimus]
ENSG00000123562(MORF4L2)	--	172.0039379	5262	160.489784	4935	159.941095	4974	195.3851923	6142	181.95021	5657	163.6307356	5171	0.987243968	0.192213016	normal	0.987920316	0.175510265	normal	0.993168408	0.047731122	normal	0.509389078	0.139930774	normal	--	--	--	K11342|0|ptr:465783|MORF4L2; mortality factor 4 like 2; K11342 mortality factor 4-like protein 2 (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	MRG	Mortality factor 4-like protein 2 GN=MORF4L2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mortality factor 4-like protein 2 [Ailuropoda melanoleuca] 
ENSG00000123570(RAB9B)	--	0.053424569	3	0.118655035	7	0.106971621	5	0.158599857	9	0.120787934	6	0.246395129	14	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07900|8.26319e-149|ptr:473711|RAB9B; RAB9B, member RAS oncogene family; K07900 Ras-related protein Rab-9B (A)"	Measles (ko05162)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-9B GN=RAB9B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-9B isoform X1 [Equus przewalskii]
ENSG00000123575(FAM199X)	--	25.20008673	1980	24.657318	2023	28.07876	2038	27.347391	2246	28.50242637	2075	23.9506941	1772	0.980234561	0.150915233	normal	0.986698686	0.015177256	normal	0.968189827	-0.209899706	normal	0.980937106	-0.00948836	normal	--	--	--	--	--	--	--	--	Protein FAM199X GN=FAM199X OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM199X isoform 1 [Ceratotherium simum simum]
ENSG00000123576(ESX1)	--	0	0	0	0	0	0	0.0754006	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K18491|2.69456e-115|pps:100971350|ESX1; ESX homeobox 1; K18491 homeobox protein ESX1 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[R]	General function prediction only	Homeobox domain	Homeobox protein ESX1-C GN=ESX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein ESX1 [Panthera tigris altaica]
ENSG00000123595(RAB9A)	--	18.141913	386	17.9565094	372	15.2611754	366	18.590588	380	15.157237	381	20.38083524	480	0.968082025	-0.053220183	normal	0.968324581	0.013009561	normal	0.782484274	0.381518765	normal	0.691636075	0.12230179	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07899|3.42411e-137|ptr:465497|RAB9A; RAB9A, member RAS oncogene family; K07899 Ras-related protein Rab-9A (A)"	Measles (ko05162)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-9A GN=RAB9A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	ras-related protein Rab-9A [Canis lupus familiaris] 
ENSG00000123600(METTL8)	--	19.09681759	830	19.81765251	816	15.88070593	802	11.74483307	547	9.808356921	424	11.70314642	513	0.042905638	-0.630952588	normal	1.36E-05	-0.963408283	normal	0.029947977	-0.651386007	normal	4.25E-06	-0.74365619	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain	Methyltransferase-like protein 8 GN=METTL8 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: methyltransferase-like protein 8 [Ceratotherium simum simum]
ENSG00000123607(TTC21B)	--	7.056832253	631	5.752718426	520	6.82338948	584	2.647227045	248	3.384212547	294	3.173211929	283	4.54E-11	-1.372597848	down	0.001201928	-0.840823788	normal	2.83E-06	-1.049467182	down	8.13E-10	-1.093147222	down	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	--	--	--	--	"Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Fis1 C-terminal tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Tetratricopeptide repeat protein 21B GN=TTC21B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 21B [Mustela putorius furo] 
ENSG00000123609(NMI)	--	7.92667801	213	9.74038641	262	7.80921	206	11.653736	323	11.2355	281	14.099134	381	0.325233784	0.566508796	normal	0.963676454	0.079135652	normal	0.001381134	0.874064484	normal	0.031663673	0.511422812	normal	--	--	--	--	--	--	--	Nmi/IFP 35 domain (NID);; Interferon-induced 35 kDa protein (IFP 35) N-terminus	N-myc-interactor GN=NMI OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: N-myc-interactor [Galeopterus variegatus]
ENSG00000123610(TNFAIP6)	--	0	0	0	0	0.228902	4	1.09396	24	1.16036	25	0.410207	9	0.000426604	4.04045235	up	0.000188753	4.121791878	up	--	--	--	--	--	--	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	--	--	[T]	Signal transduction mechanisms	CUB domain;; Extracellular link domain	Tumor necrosis factor-inducible gene 6 protein (Precursor) GN=TNFAIP6 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: tumor necrosis factor-inducible gene 6 protein [Tupaia chinensis] 
ENSG00000123612(ACVR1C)	--	0.226237525	26	0.236780249	22	0.158016724	18	0.025421045	3	0.0510473	1	0.079287761	9	0.013327276	-2.626459099	normal	0.006608773	-3.24064296	down	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K13568|0|mcf:102131774|ACVR1C; activin A receptor, type IC; K13568 activin receptor type-1C [EC:2.7.11.30] (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Transforming growth factor beta type I GS-motif;; Activin types I and II receptor domain	Activin receptor type-1C (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: activin receptor type-1C isoform X1 [Lipotes vexillifer]
ENSG00000123636(BAZ2B)	--	6.728206583	759	8.795666285	802	4.511703455	801	5.79106951	657	5.051736149	891	5.248108653	702	0.937173588	-0.238519242	normal	0.969480429	0.130163702	normal	0.953998968	-0.198222578	normal	0.727240015	-0.090909752	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	--	--	[B]	Chromatin structure and dynamics	Bromodomain;; Methyl-CpG binding domain;; DDT domain;; PHD-finger	Bromodomain adjacent to zinc finger domain protein 2B GN=BAZ2B OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: bromodomain adjacent to zinc finger domain protein 2B isoform X1 [Sorex araneus]
ENSG00000123643(SLC36A1)	--	3.741641459	351	4.208962282	375	3.362029386	295	6.7517598	565	6.035249353	556	7.768499516	715	0.045357635	0.653673035	normal	0.268182079	0.544952183	normal	1.04E-09	1.264638003	up	6.33E-05	0.825706731	normal	--	--	--	"K14209|0|hsa:206358|SLC36A1, Dct1, LYAAT1, PAT1, TRAMD3; solute carrier family 36 (proton/amino acid symporter), member 1; K14209 solute carrier family 36 (proton-coupled amino acid transporter) (A)"	Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Proton-coupled amino acid transporter 1 GN=SLC36A1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: proton-coupled amino acid transporter 1 [Felis catus] 
ENSG00000123684(LPGAT1)	--	20.324793	2413	24.297013	2889	20.96232	2379	23.80954	2849	22.53887574	2610	24.75754502	2882	0.974334006	0.208673059	normal	0.981464522	-0.167854462	normal	0.955325439	0.26826846	normal	0.660985852	0.097503046	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13514|0|hsa:9926|LPGAT1, FAM34A, FAM34A1, NET8; lysophosphatidylglycerol acyltransferase 1; K13514 lysophosphatidylglycerol acyltransferase 1 [EC:2.3.1.-] (A)"	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	Acyl-CoA:lysophosphatidylglycerol acyltransferase 1 GN=LPGAT1 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-CoA:lysophosphatidylglycerol acyltransferase 1 isoform 1 [Ceratotherium simum simum] 
ENSG00000123685(BATF3)	--	7.737208	147	5.309768	111	9.3270458	187	7.629688	150	7.413127	142	5.394606	104	0.967967398	-0.001668653	normal	0.919186416	0.329922023	normal	0.033667622	-0.845446304	normal	0.708707501	-0.189747183	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09034|5.96789e-58|bta:535008|BATF3; basic leucine zipper transcription factor, ATF-like 3; K09034 ATF-like basic leucine zipper transcriptional factor (A)"	--	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Basic leucine zipper transcriptional factor ATF-like 3 GN=BATF3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	basic leucine zipper transcriptional factor ATF-like 3 [Bos taurus] 
ENSG00000123689(G0S2)	--	3.55802	51	1.06796	16	1.56083	23	4.76708	70	4.677	67	5.36213	78	0.941896391	0.415309301	normal	0.000103317	1.947730378	up	0.000260443	1.689715856	up	0.005963389	1.235066178	up	--	--	--	--	--	--	--	G0/G1 switch protein 2	G0/G1 switch protein 2 GN=G0S2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: G0/G1 switch protein 2 [Elephantulus edwardii]
ENSG00000123700(KCNJ2)	--	2.729684943	237	2.978400789	260	2.123275	182	0.739421784	64	1.06243828	92	2.296859675	203	1.37E-12	-1.894211426	down	8.91E-09	-1.504842218	down	0.958211036	0.148084237	normal	0.089329636	-0.937786706	normal	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04996|0|ptg:102967064|KCNJ2; potassium inwardly-rectifying channel, subfamily J, member 2; K04996 potassium inwardly-rectifying channel subfamily J member 2 (A)"	Cholinergic synapse (ko04725);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel;; Inward rectifier potassium channel N-terminal	Inward rectifier potassium channel 2 GN=KCNJ2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: inward rectifier potassium channel 2 [Felis catus] 
ENSG00000123728(RAP2C)	--	19.69475934	1034	20.94497857	1075	19.61007283	1018	19.80027961	1055	21.76663617	1134	20.28341014	1073	0.980050003	-0.001822769	normal	0.979132284	0.055581291	normal	0.978415374	0.067523359	normal	0.890790288	0.039804692	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07839|2.3479e-120|umr:103672940|RAP2C; RAP2C, member of RAS oncogene family; K07839 Ras-related protein Rap-2C (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein Rap-2c (Precursor) GN=RAP2C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Rap-2c isoform X1 [Ailuropoda melanoleuca] 
ENSG00000123737(EXOSC9)	--	17.40388193	450	18.126619	487	20.61991	546	18.71565	506	21.46716012	559	17.00879251	452	0.961619007	0.137935834	normal	0.954196229	0.17698666	normal	0.908309334	-0.280015869	normal	0.98150443	0.011535223	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K03678|0|hsa:5393|EXOSC9, PM/Scl-75, PMSCL1, RRP45, Rrp45p, p5, p6; exosome component 9 (EC:3.1.13.-); K03678 exosome complex component RRP45 (A)"	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	"3' exoribonuclease family, domain 1;; 3' exoribonuclease family, domain 2"	Exosome complex component RRP45 GN=EXOSC9 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component RRP45 isoform X1 [Camelus ferus]
ENSG00000123739(PLA2G12A)	--	4.75714715	392	5.0224905	416	5.304149036	431	4.40300529	368	3.998575688	329	4.451632772	370	0.962109851	-0.121488566	normal	0.83006712	-0.358453482	normal	0.936717434	-0.227591262	normal	0.356948612	-0.236734569	normal	--	--	Molecular Function: phospholipase A2 activity (GO:0004623);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid catabolic process (GO:0016042);; 	"K01047|6.65651e-112|nle:100591114|PLA2G12A; phospholipase A2, group XIIA; K01047 secretory phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; Pancreatic secretion (ko04972);; Fat digestion and absorption (ko04975)	--	--	Group XII secretory phospholipase A2 precursor (PLA2G12)	Group XIIA secretory phospholipase A2 (Precursor) GN=PLA2G12A OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: group XIIA secretory phospholipase A2 [Lipotes vexillifer]
ENSG00000123810(B9D2)	--	7.36039	115	9.04287	145	8.94554	145	7.7252	121	8.81748	137	10.5084	166	0.96908463	0.041993954	normal	0.963577349	-0.10220671	normal	0.954903303	0.185034037	normal	0.946734065	0.046059666	normal	--	--	--	"K16745|1.16045e-125|hsa:80776|B9D2, ICIS-1, MKS10, MKSR2; B9 protein domain 2; K16745 B9 domain-containing protein 2 (A)"	--	[S]	Function unknown	"Ciliary basal body-associated, B9 protein"	B9 domain-containing protein 2 GN=B9D2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: B9 domain-containing protein 2 isoform X2 [Myotis brandtii]
ENSG00000123815(COQ8B)	--	36.66975105	1077	33.97388364	936	45.12515801	1067	22.54094828	688	19.36051179	692	32.921362	866	0.012798453	-0.676152142	normal	0.53796805	-0.456302069	normal	0.89220618	-0.308925748	normal	0.002871362	-0.475952893	normal	[R]	General function prediction only	--	K08869|0|pps:100986186|ADCK4; aarF domain containing kinase 4; K08869 aarF domain-containing kinase (A)	--	[R]	General function prediction only	ABC1 family	AarF domain-containing protein kinase 4 GN=ADCK4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: uncharacterized aarF domain-containing protein kinase 4 [Vicugna pacos]
ENSG00000123836(PFKFB2)	--	4.867839	546	6.499069097	711	5.322653	601	6.657536	732	5.546992	612	11.957822	1312	0.742681295	0.391156912	normal	0.936821457	-0.237200067	normal	1.42E-08	1.116090863	up	0.488156383	0.495954868	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: 6-phosphofructo-2-kinase activity (GO:0003873);; Molecular Function: ATP binding (GO:0005524);; Biological Process: fructose metabolic process (GO:0006000);; 	"K01103|0|ggo:101134985|PFKFB2; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 2 isoform 1; K19029 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 2 [EC:2.7.1.105 3.1.3.46] (A)"	Fructose and mannose metabolism (ko00051);; HIF-1 signaling pathway (ko04066);; AMPK signaling pathway (ko04152)	[G]	Carbohydrate transport and metabolism	6-phosphofructo-2-kinase;; Histidine phosphatase superfamily (branch 1);; AAA domain;; Chromatin associated protein KTI12	"Fructose-2,6-bisphosphatase GN=PFKFB2 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 isoform X7 [Canis lupus familiaris]"
ENSG00000123838(C4BPA)	--	0	0	0.077035987	3	0	0	0.254833177	10	1.73961744	52	0.992903968	39	--	--	--	2.39E-08	3.550409651	up	3.54E-08	4.739569182	up	--	--	--	--	--	--	"K04002|0|hsa:722|C4BPA, C4BP, PRP; complement component 4 binding protein, alpha; K04002 complement component 4 binding protein, alpha (A)"	Complement and coagulation cascades (ko04610);; Pertussis (ko05133)	--	--	Sushi domain (SCR repeat)	C4b-binding protein alpha chain (Precursor) GN=C4BPA OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: C4b-binding protein alpha chain [Galeopterus variegatus]
ENSG00000123843(C4BPB)	--	0.0723511	1	0	0	0	0	0.540170935	7	0.318118163	3	0.118287096	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04003|4.95626e-175|hsa:725|C4BPB, C4BP; complement component 4 binding protein, beta; K04003 complement component 4 binding protein, beta (A)"	Complement and coagulation cascades (ko04610);; Pertussis (ko05133)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Sushi domain (SCR repeat)	C4b-binding protein beta chain (Precursor) GN=C4BPB OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C4b-binding protein beta chain isoform X1 [Galeopterus variegatus]
ENSG00000123892(RAB38)	--	0.177096988	4	0.0871121	2	0.043380462	0	1.74531398	40	2.206161	48	1.488760736	32	6.35E-05	2.881360385	up	2.90E-08	3.800823498	up	2.37E-06	4.46593213	up	2.57E-10	4.297809246	up	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07923|1.58873e-157|ptr:451468|RAB38; RAB38, member RAS oncogene family; K07923 Ras-related protein Rab-38 (A)"	--	[T]	Signal transduction mechanisms	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-38 GN=RAB38 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-38 [Ailuropoda melanoleuca] 
ENSG00000123901(GPR83)	--	0.0133097	1	0	0	0	0	0.029546396	2	0.087056958	2	0.039634131	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04210|0|hsa:10888|GPR83, GIR, GPR72; G protein-coupled receptor 83; K04210 G protein-coupled receptor 83 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Probable G-protein coupled receptor 83 (Precursor) GN=GPR83 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 83 [Ceratotherium simum simum]
ENSG00000123908(AGO2)	--	12.66480102	2362	10.73527294	2485	10.88284922	2473	11.02515215	2589	17.76513488	2566	11.50072398	2702	0.986160993	0.101490669	normal	0.988450434	0.024833888	normal	0.98549548	0.119404118	normal	0.728258727	0.081092791	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	"K11593|0|cjc:100390940|AGO2, EIF2C2; argonaute RISC catalytic component 2; K11593 eukaryotic translation initiation factor 2C (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Piwi domain;; PAZ domain;; Domain of unknown function (DUF1785)	Protein argonaute-2 {ECO:0000255|HAMAP-Rule:MF_03031} GN=AGO2 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: protein argonaute-2 [Bubalus bubalis]
ENSG00000123933(MXD4)	--	7.65307	575	6.8479	527	6.80599	526	10.3891	777	12.8436	962	10.4422	789	0.711061358	0.402591988	normal	0.000279008	0.84498696	normal	0.127731501	0.575311561	normal	0.000170336	0.613796542	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09114|9.94925e-132|hsa:10608|MXD4, MAD4, MST149, MSTP149, bHLHc12; MAX dimerization protein 4; K09114 MAX dimerization protein (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Max dimerization protein 4 GN=MXD4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: max dimerization protein 4 [Loxodonta africana]
ENSG00000123975(CKS2)	--	213.895	1332	193.656	1211	210.025	1326	231.716	1519	228.214	1418	243.904	1566	0.973505017	0.158524213	normal	0.961813506	0.205994187	normal	0.955579001	0.231468818	normal	0.288670528	0.197890896	normal	--	--	--	K02219|3.71031e-51|tup:102498105|CKS2; CDC28 protein kinase regulatory subunit 2; K02219 cyclin-dependent kinase regulatory subunit CKS1 (A)	Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cyclin-dependent kinase regulatory subunit	Cyclin-dependent kinases regulatory subunit 2 GN=CKS2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: uncharacterized protein LOC100915745 isoform 1 [Sarcophilus harrisii] 
ENSG00000123977(DAW1)	--	0.207597053	6	0.271223584	9	0.237772656	6	0.342360545	12	0.235761422	8	0.140484558	5	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	[A]	RNA processing and modification	"WD domain, G-beta repeat;; Nucleoporin Nup120/160;; Eukaryotic translation initiation factor eIF2A"	Dynein assembly factor with WDR repeat domains 1 GN=DAW1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: outer row dynein assembly protein 16 homolog [Ceratotherium simum simum]
ENSG00000123983(ACSL3)	--	90.46185364	5194	101.5670754	5855	89.482494	5463	51.8593871	3126	44.6405907	2644	84.25605058	4877	0.000828968	-0.763066146	normal	3.17E-10	-1.167912304	down	0.98815524	-0.171940487	normal	0.023378003	-0.652981108	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K01897|0|ptr:459974|ACSL3; acyl-CoA synthetase long-chain family member 3; K01897 long-chain acyl-CoA synthetase [EC:6.2.1.3] (A)	Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	AMP-binding enzyme	Long-chain-fatty-acid--CoA ligase 3 GN=ACSL3 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: long-chain-fatty-acid--CoA ligase 3 isoform X1 [Galeopterus variegatus]
ENSG00000123989(CHPF)	--	30.71420438	1508	24.20838	1222	26.43743888	1382	22.238578	1089	20.916302	1057	21.44524288	1065	0.330615495	-0.499862445	normal	0.950678897	-0.230388584	normal	0.772403705	-0.383715901	normal	0.01750989	-0.378013992	normal	--	--	Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: Golgi cisterna membrane (GO:0032580);; 	K00747|0|ptr:743513|CHPF; chondroitin polymerizing factor; K00747 chondroitin polymerizing factor [EC:2.4.1.175 2.4.1.226] (A)	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[S]	Function unknown	Chondroitin N-acetylgalactosaminyltransferase	Chondroitin sulfate synthase 2 GN=CHPF OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: chondroitin sulfate synthase 2 isoform 1 [Ceratotherium simum simum]
ENSG00000123992(DNPEP)	--	28.926247	918	24.82410044	794	24.78182382	798	15.31102854	522	20.01636568	568	16.00751629	541	0.000220919	-0.843378007	normal	0.362155544	-0.503534988	normal	0.142643613	-0.567736435	normal	7.38E-05	-0.643067911	normal	[E]	Amino acid transport and metabolism	Molecular Function: aminopeptidase activity (GO:0004177);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	K01267|0|mcc:703180|DNPEP; aspartyl aminopeptidase; K01267 aspartyl aminopeptidase [EC:3.4.11.21] (A)	--	[E]	Amino acid transport and metabolism	Aminopeptidase I zinc metalloprotease (M18);; M42 glutamyl aminopeptidase	Aspartyl aminopeptidase GN=DNPEP OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: aspartyl aminopeptidase isoform X4 [Canis lupus familiaris]
ENSG00000123999(INHA)	--	0.857596	23	0.682282	19	0.600394	16	0.297141	8	0.36519	9	0.332328	9	0.791307961	-1.390784608	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K05500|0|hsa:3623|INHA; inhibin, alpha; K05500 inhibin, alpha (A)"	--	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain	Inhibin alpha chain (Precursor) GN=INHA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inhibin alpha chain [Galeopterus variegatus]
ENSG00000124006(OBSL1)	--	12.47451096	927	12.9792392	986	12.62407192	955	9.309354628	672	11.57987362	847	10.96484015	797	0.365997831	-0.493974094	normal	0.941615276	-0.240254205	normal	0.92429074	-0.26874593	normal	0.060376359	-0.329042943	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Penicillin-Binding Protein C-terminus Family;; Immunoglobulin C1-set domain;; Alphaherpesvirus glycoprotein E	Obscurin-like protein 1 GN=OBSL1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	obscurin-like protein 1 [Oryctolagus cuniculus] 
ENSG00000124067(SLC12A4)	--	11.6037087	992	11.50396619	1048	12.05051117	1116	11.10025784	948	12.0425739	1022	10.21616155	877	0.975464088	-0.096132992	normal	0.978262848	-0.057585927	normal	0.826170612	-0.355435019	normal	0.407082758	-0.16985832	normal	[E]	Amino acid transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14427|0|mcc:701196|SLC12A4; solute carrier family 12 (potassium/chloride transporters), member 4; K14427 solute carrier family 12 (potassium/chloride transporter), member 4/5/6 (A)"	--	[P]	Inorganic ion transport and metabolism	Amino acid permease;; Amino acid permease;; K-Cl Co-transporter type 1 (KCC1)	Solute carrier family 12 member 4 GN=SLC12A4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 12 member 4 isoform 3 [Odobenus rosmarus divergens]
ENSG00000124074(ENKD1)	--	3.863361	115	3.105457866	93	3.025994805	95	5.503068	164	4.938181605	148	4.006104616	123	0.782961941	0.475881621	normal	0.480885352	0.640543459	normal	0.91803399	0.359327453	normal	0.170041891	0.49955051	normal	--	--	--	--	--	--	--	Calmodulin-binding	Enkurin domain-containing protein 1 GN=ENKD1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: enkurin domain-containing protein 1 [Eptesicus fuscus]
ENSG00000124089(MC3R)	--	0	0	0	0	0.140886	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04201|0|ptr:469978|MC3R; melanocortin 3 receptor; K04201 melanocortin 3 receptor (A)	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Melanocortin receptor 3 GN=MC3R OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: melanocortin receptor 3 [Galeopterus variegatus]
ENSG00000124091(GCNT7)	--	0.0472576	1	0	0	0.14197	2	0.0934672	2	0.0953152	2	0.0465853	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; 	--	--	[G]	Carbohydrate transport and metabolism	Core-2/I-Branching enzyme	"Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 GN=GCNT7 OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7 [Galeopterus variegatus]"
ENSG00000124092(CTCFL)	--	0.034768247	1	0	0	0.03375651	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Transcriptional repressor CTCFL GN=CTCFL OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcriptional repressor CTCFL [Ceratotherium simum simum]
ENSG00000124098(FAM210B)	--	15.915419	753	13.2108	634	16.4726	783	11.061446	526	10.6457	509	11.1978	538	0.199219207	-0.547075766	normal	0.850639799	-0.337343662	normal	0.194145616	-0.548412055	normal	0.00575232	-0.485056858	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1279)	Protein FAM210B GN=FAM210B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM210B isoform X1 [Tupaia chinensis]
ENSG00000124102(PI3)	--	0	0	0.175994	1	0.681828	3	0.507296	3	0.172516	0	1.02225	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Molecular Function: peptidase inhibitor activity (GO:0030414);; 	--	--	--	--	Trappin protein transglutaminase binding domain;; WAP-type (Whey Acidic Protein) 'four-disulfide core'	Elafin (Precursor) GN=PI3 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: elafin [Galeopterus variegatus]
ENSG00000124103(FAM209A)	--	0.417716	5	0.582599	7	0.407168	4	0	0	0.161979	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM209 family	Protein FAM209A (Precursor) GN=FAM209A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM209B isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000124104(SNX21)	--	5.902660896	332	5.30173379	295	6.87448367	286	4.729954724	200	5.7110118	251	4.628361	210	0.019650187	-0.757447286	normal	0.926754426	-0.253046055	normal	0.697826853	-0.45112213	normal	0.048245856	-0.487042781	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17932|0|pps:100968307|SNX21; sorting nexin family member 21; K17932 sorting nexin-21 (A)	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	PX domain;; TPR repeat	Sorting nexin-21 GN=SNX21 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-21 [Equus caballus] 
ENSG00000124107(SLPI)	--	2.8886	19	4.06088	27	0.587826	3	4.90468	34	10.6913	70	20.878	141	0.932640442	0.762099774	normal	0.028114	1.305975592	normal	0	4.974225822	up	0.102234319	2.302342647	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Molecular Function: peptidase inhibitor activity (GO:0030414);; 	--	--	--	--	WAP-type (Whey Acidic Protein) 'four-disulfide core'	Antileukoproteinase (Precursor) GN=SLPI OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: antileukoproteinase [Balaenoptera acutorostrata scammoni]
ENSG00000124116(WFDC3)	--	0	0	0	0	0	0	0.16500042	1	0.17056252	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Molecular Function: peptidase inhibitor activity (GO:0030414);; 	--	--	--	--	WAP-type (Whey Acidic Protein) 'four-disulfide core'	WAP four-disulfide core domain protein 3 (Precursor) GN=WFDC3 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	"PREDICTED: WAP four-disulfide core domain protein 3, partial [Galeopterus variegatus]"
ENSG00000124120(TTPAL)	--	7.0259997	740	6.812961741	748	7.105516054	792	7.005612527	741	6.762375129	756	7.9372937	892	0.975704114	-0.028824186	normal	0.975671798	-0.006066394	normal	0.964533327	0.162958481	normal	0.878949981	0.046840756	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	"CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain;; Divergent CRAL/TRIO domain"	Alpha-tocopherol transfer protein-like GN=TTPAL OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: alpha-tocopherol transfer protein-like [Galeopterus variegatus]
ENSG00000124126(PREX1)	--	3.355019645	498	2.492058897	364	3.23488964	452	3.417962031	516	4.254636535	641	2.588398	368	0.971689349	0.020331438	normal	0.002320481	0.792447117	normal	0.889725295	-0.30377995	normal	0.696661854	0.193114482	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12365|0|hsa:57580|PREX1, P-REX1; phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1; K12365 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchanger 1 protein (A)"	Chemokine signaling pathway (ko04062)	--	--	"RhoGEF domain;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; PDZ domain (Also known as DHR or GLGF);; PH domain"	"Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein GN=PREX1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein isoform X2 [Galeopterus variegatus]"
ENSG00000124134(KCNS1)	--	0.012328308	1	0	0	0.055776393	1	0.029055258	1	0.011980443	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04931|0|hsa:3787|KCNS1, KV9.1; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1; K04931 potassium voltage-gated channel delayed-rectifier subfamily S member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily S member 1 GN=KCNS1 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	potassium voltage-gated channel subfamily S member 1 [Bos taurus] 
ENSG00000124140(SLC12A5)	--	14.38734857	43	15.36808954	44	9.561060801	38	6.598283846	26	4.283962948	18	6.057292037	20	0.902261145	-0.723083828	normal	0.334443041	-1.242113532	normal	0.857646795	-0.884981748	normal	0.083883881	-0.988186445	normal	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Biological Process: ion transport (GO:0006811);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14427|0|pon:100456689|SLC12A5; solute carrier family 12 (potassium/chloride transporter), member 5; K14427 solute carrier family 12 (potassium/chloride transporter), member 4/5/6 (A)"	--	[P]	Inorganic ion transport and metabolism	Amino acid permease;; Amino acid permease	Solute carrier family 12 member 5 GN=SLC12A5 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 12 member 5 isoform X1 [Galeopterus variegatus]
ENSG00000124145(SDC4)	--	45.1687	1730	38.331	1499	44.0181	1693	46.3854	1803	34.913	1322	31.566	1208	0.985464207	0.028770067	normal	0.96417877	-0.202487063	normal	0.357116221	-0.494727231	normal	0.482596184	-0.206270384	normal	--	--	--	"K16338|3.89063e-109|hsa:6385|SDC4, SYND4; syndecan 4; K16338 syndecan 4 (A)"	ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Proteoglycans in cancer (ko05205)	--	--	Syndecan domain	Syndecan-4 (Precursor) GN=SDC4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: syndecan-4 [Canis lupus familiaris]
ENSG00000124151(NCOA3)	--	51.560897	7656	58.418961	8631	46.192178	6737	31.80762108	4720	31.539571	4649	43.02919945	6374	0.002788078	-0.728448072	normal	9.34E-06	-0.913812031	normal	0.993755507	-0.08817837	normal	0.010762721	-0.569089543	normal	--	--	"Molecular Function: transcription coactivator activity (GO:0003713);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: nuclear hormone receptor binding (GO:0035257);; "	"K11256|0|hsa:8202|NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP; nuclear receptor coactivator 3 (EC:2.3.1.48); K11256 nuclear receptor coactivator 3 [EC:2.3.1.48] (A)"	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	PAS domain;; Nuclear receptor coactivator;; Steroid receptor coactivator;; Domain of unknown function (DUF1518);; PAS fold;; PAS domain	Nuclear receptor coactivator 3 GN=NCOA3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor coactivator 3 [Galeopterus variegatus]
ENSG00000124155(PIGT)	--	49.468258	1890	46.83779946	1731	45.509066	1719	44.0951552	1744	47.78712778	1818	48.11433601	1825	0.97872291	-0.146694265	normal	0.984695189	0.049277907	normal	0.983966386	0.077968898	normal	0.982012688	-0.008468381	normal	--	--	Biological Process: attachment of GPI anchor to protein (GO:0016255);; Cellular Component: GPI-anchor transamidase complex (GO:0042765);; 	"K05292|0|ggo:101139081|PIGT; GPI transamidase component PIG-T; K05292 phosphatidylinositol glycan, class T (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[MO]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	"Gpi16 subunit, GPI transamidase component"	GPI transamidase component PIG-T (Precursor) GN=PIGT OS=Homo sapiens (Human) PE=1 SV=1	MO	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: GPI transamidase component PIG-T isoform X1 [Tupaia chinensis]
ENSG00000124159(MATN4)	--	0.029923692	1	0.059634832	2	0.02896724	0	0.042607961	1	0.041940808	0	0.030398982	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	von Willebrand factor type A domain;; von Willebrand factor type A domain;; Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; EGF-like domain;; Trimeric coiled-coil oligomerisation domain of matrilin;; von Willebrand factor type A domain	Matrilin-4 (Precursor) GN=MATN4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: matrilin-4 [Galeopterus variegatus]
ENSG00000124160(NCOA5)	--	11.73188375	752	12.81354171	812	10.39973249	667	12.21924791	779	13.9051436	848	12.89830092	828	0.97626483	0.020018219	normal	0.97619215	0.041083107	normal	0.892393685	0.303034768	normal	0.63024338	0.116764301	normal	--	--	--	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	--	Nuclear receptor coactivator 5 GN=NCOA5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor coactivator 5 [Leptonychotes weddellii]
ENSG00000124164(VAPB)	--	23.0109686	1331	25.123952	1391	24.7662889	1314	25.19159479	1388	24.861678	1384	22.610699	1268	0.982714444	0.029631238	normal	0.982561533	-0.028673782	normal	0.981282911	-0.059632103	normal	0.951909417	-0.02007893	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K10707|1.13579e-163|ptr:469984|VAPB; VAMP (vesicle-associated membrane protein)-associated protein B and C; K10707 vesicle-associated membrane protein-associated protein B (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	MSP (Major sperm protein) domain	Vesicle-associated membrane protein-associated protein B/C GN=VAPB OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein-associated protein B/C isoform 2 [Dasypus novemcinctus]
ENSG00000124171(PARD6B)	--	3.336309	218	3.371458	220	2.982694	175	3.199507807	210	2.780186	181	4.21851	274	0.964186653	-0.084166613	normal	0.910837462	-0.30065778	normal	0.198129026	0.634114875	normal	0.832826563	0.096640375	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06093|0|nle:100597121|PARD6B; par-6 partitioning defective 6 homolog beta (C. elegans); K06093 partitioning defective protein 6 (A)	Rap1 signaling pathway (ko04015);; Endocytosis (ko04144);; Hippo signaling pathway (ko04390);; Tight junction (ko04530)	[T]	Signal transduction mechanisms	PB1 domain;; PDZ domain (Also known as DHR or GLGF)	Partitioning defective 6 homolog beta GN=PARD6B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: partitioning defective 6 homolog beta [Camelus bactrianus] 
ENSG00000124172(ATP5E)	--	27.33670717	1394	31.64268907	1617	30.65940007	1547	32.62130205	1712	26.39168609	1341	30.75664916	1554	0.941494255	0.2653556	normal	0.924189619	-0.291137505	normal	0.98441869	-0.001776403	normal	0.987079908	-0.006148886	normal	--	--	--	"K02135|7.37394e-29|hsa:514|ATP5E, ATPE, MC5DN3; ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit (EC:3.6.3.14); K02135 F-type H+-transporting ATPase subunit epsilon (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Mitochondrial ATP synthase epsilon chain	"ATP synthase subunit epsilon, mitochondrial GN=ATP5E OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: ATP synthase subunit epsilon, mitochondrial [Odobenus rosmarus divergens] "
ENSG00000124177(CHD6)	--	7.425019848	1627	8.500465889	1628	6.7800072	1641	6.131599689	1483	6.553070303	1506	7.097395381	1573	0.973956718	-0.164365256	normal	0.977895687	-0.133676338	normal	0.983317367	-0.06928279	normal	0.56331362	-0.122933376	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14436|0|hsa:84181|CHD6, CHD-6, CHD5, RIGB; chromodomain helicase DNA binding protein 6 (EC:3.6.4.12); K14436 chromodomain-helicase-DNA-binding protein 6 [EC:3.6.4.12] (A)"	--	[K]	Transcription	"SNF2 family N-terminal domain;; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; BRK domain;; DEAD/DEAH box helicase"	Chromodomain-helicase-DNA-binding protein 6 GN=CHD6 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: chromodomain-helicase-DNA-binding protein 6 [Galeopterus variegatus]
ENSG00000124181(PLCG1)	--	16.292892	1942	14.5522115	1759	15.37561311	1847	16.475209	1964	18.30664258	2185	15.481565	1848	0.986601458	-0.014569073	normal	0.934147144	0.291226213	normal	0.986134082	-0.007504409	normal	0.689364644	0.090998149	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: protein binding (GO:0005515);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K01116|0|hsa:5335|PLCG1, NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1; phospholipase C, gamma 1 (EC:3.1.4.11); K01116 phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Phosphatidylinositol signaling system (ko04070);; VEGF signaling pathway (ko04370);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Inflammatory mediator regulation of TRP channels (ko04750);; Thyroid hormone signaling pathway (ko04919);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	"Phosphatidylinositol-specific phospholipase C, X domain;; SH2 domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; PH domain;; C2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Phosphoinositide-specific phospholipase C, efhand-like"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 GN=PLCG1 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1 [Tupaia chinensis]"
ENSG00000124191(TOX2)	--	14.748314	576	8.246443084	332	10.26105579	470	7.129941991	280	9.167513828	368	5.574674276	201	1.67E-06	-1.06729733	down	0.960053316	0.126548288	normal	5.41E-08	-1.227533104	down	0.117468711	-0.720379022	normal	--	--	--	--	--	[R]	General function prediction only	HMG (high mobility group) box;; HMG-box domain	TOX high mobility group box family member 2 GN=TOX2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: TOX high mobility group box family member 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000124193(SRSF6)	--	59.531973	3655	54.70184	3331	52.511381	3169	54.264014	3461	66.304123	4089	52.989949	3281	0.989055274	-0.10946743	normal	0.962539251	0.274253604	normal	0.990408383	0.041796889	normal	0.76783972	0.071587083	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12893|4.91844e-109|mdo:100028254|SRSF6; serine/arginine-rich splicing factor 6; K12893 splicing factor, arginine/serine-rich 4/5/6 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Serine/arginine-rich splicing factor 6 GN=SRSF6 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 6 [Monodelphis domestica]
ENSG00000124194(GDAP1L1)	--	0.071280909	1	0.02042457	1	0.060141294	2	0.095882163	2	0.019433116	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Ganglioside-induced differentiation-associated protein 1-like 1 GN=GDAP1L1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: ganglioside-induced differentiation-associated protein 1-like 1 isoform X1 [Vicugna pacos]
ENSG00000124198(ARFGEF2)	--	13.17047119	2214	16.8081703	2836	14.4270598	2406	13.03351279	2198	12.310954	2071	16.833317	2832	0.987341152	-0.041267357	normal	0.512173406	-0.474659015	normal	0.969971451	0.226761672	normal	0.801752975	-0.09097755	normal	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K18442|0|hsa:10564|ARFGEF2, BIG2, PVNH2, dJ1164I10.1; ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited); K18442 brefeldin A-inhibited guanine nucleotide-exchange protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; Guanine nucleotide exchange factor in Golgi transport N-terminal;; Domain of unknown function (DUF1981)	Brefeldin A-inhibited guanine nucleotide-exchange protein 2 GN=ARFGEF2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: brefeldin A-inhibited guanine nucleotide-exchange protein 2 [Canis lupus familiaris]
ENSG00000124201(ZNFX1)	--	13.162191	2205	12.225364	2054	13.58266469	2272	15.718312	2616	15.42117501	2551	15.906933	2655	0.971181511	0.215613564	normal	0.93967652	0.291007581	normal	0.971455153	0.21632426	normal	0.167109206	0.23921034	normal	[L]	"Replication, recombination and repair"	--	--	--	[L]	"Replication, recombination and repair"	AAA domain;; AAA domain;; Part of AAA domain;; AAA domain	NFX1-type zinc finger-containing protein 1 GN=ZNFX1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: NFX1-type zinc finger-containing protein 1 [Ursus maritimus]
ENSG00000124205(EDN3)	--	0	0	0	0	0	0	0.047216061	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: regulation of vasoconstriction (GO:0019229);; 	K05227|1.98727e-159|pps:100980599|EDN3; endothelin 3; K05227 endothelin-3 (A)	--	--	--	Endothelin family	Endothelin-3 (Precursor) GN=EDN3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endothelin-3 [Galeopterus variegatus]
ENSG00000124207(CSE1L)	--	84.225491	4763	81.162546	4534	91.121071	5023	91.668182	5225	86.359305	4860	72.549412	4109	0.991817366	0.10269659	normal	0.991911795	0.078720002	normal	0.956763213	-0.297954028	normal	0.903659729	-0.034484954	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	K18423|0|ptg:102971571|CSE1L; CSE1 chromosome segregation 1-like (yeast); K18423 exportin-2 (importin alpha re-exporter) (A)	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	"CAS/CSE protein, C-terminus;; Cse1;; Importin-beta N-terminal domain"	Exportin-2 GN=CSE1L OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exportin-2 [Felis catus] 
ENSG00000124208(TMEM189-UBE2V1)	--	104.9838012	3729	104.7709203	3717	110.312442	3850	119.4331086	4274	108.0962224	3864	105.4237555	3807	0.986223912	0.165901965	normal	0.991368444	0.034516075	normal	0.991780089	-0.024485646	normal	0.816737675	0.059090835	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K10704|0|hsa:387522|TMEM189-UBE2V1, CROC-1B, CROC1B, KUA-UEV; TMEM189-UBE2V1 readthrough; K10704 ubiquitin-conjugating enzyme E2 variant (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Kua-ubiquitin conjugating enzyme hybrid localisation domain;; Ubiquitin-conjugating enzyme	Transmembrane protein 189 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	hypothetical protein PANDA_000798 [Ailuropoda melanoleuca]
ENSG00000124209(RAB22A)	--	6.95742	884	6.74479	854	6.95627	866	7.27238	930	6.75577	859	7.33989	936	0.977713917	0.042280437	normal	0.977177335	-0.012981576	normal	0.973903964	0.103675879	normal	0.880865219	0.044322918	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07891|2.46688e-143|hsa:57403|RAB22A; RAB22A, member RAS oncogene family; K07891 Ras-related protein Rab-22 (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	Ras-related protein Rab-22A GN=RAB22A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-22A [Orcinus orca] 
ENSG00000124212(PTGIS)	--	0	0	0	0	0	0	0	0	0	0	0.0191091	2	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K01831|0|hsa:5740|PTGIS, CYP8, CYP8A1, PGIS, PTGI; prostaglandin I2 (prostacyclin) synthase (EC:5.3.99.4); K01831 prostacyclin synthase [EC:5.3.99.4] (A)"	Arachidonic acid metabolism (ko00590)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Prostacyclin synthase GN=PTGIS OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: prostacyclin synthase [Lipotes vexillifer]
ENSG00000124214(STAU1)	--	44.09469581	2959	41.88491065	2736	39.49496955	2591	47.25914872	3118	47.17757965	3082	40.0680459	2651	0.989929277	0.044656379	normal	0.984000955	0.150293769	normal	0.989063684	0.024721947	normal	0.756831658	0.073380426	normal	--	--	--	K17597|0|cjc:100393512|STAU1; staufen double-stranded RNA binding protein 1; K17597 double-stranded RNA-binding protein Staufen (A)	--	[UK]	"Intracellular trafficking, secretion, and vesicular transport;; Transcription"	Double-stranded RNA binding motif;; double strand RNA binding domain from DEAD END PROTEIN 1	Double-stranded RNA-binding protein Staufen homolog 1 GN=STAU1 OS=Homo sapiens (Human) PE=1 SV=2	KU	"Transcription;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: double-stranded RNA-binding protein Staufen homolog 1 isoform X2 [Camelus ferus] 
ENSG00000124215(CDH26)	--	0.123834919	6	0.142947927	9	0.245226017	8	0.06388574	4	0.031088651	1	0.063051923	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Cadherin domain	Cadherin-like protein 26 (Precursor) GN=CDH26 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: cadherin-like protein 26 [Ceratotherium simum simum]
ENSG00000124216(SNAI1)	--	2.39546	68	0.789722	22	0.936488	26	1.85059	52	1.33381	38	0.869063	25	0.944025104	-0.407297001	normal	0.919717764	0.728559037	normal	0.98634879	-0.06124203	normal	0.990396904	-0.036465323	normal	[R]	General function prediction only	--	"K05707|1.83174e-176|hsa:6615|SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1; snail family zinc finger 1; K05707 snail 1 (A)"	Adherens junction (ko04520)	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein SNAI1 GN=SNAI1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein SNAI1 [Galeopterus variegatus]
ENSG00000124217(MOCS3)	--	3.45613	279	3.81146	309	3.50166	280	4.43621	360	4.34508	350	4.61401	373	0.86503735	0.335270522	normal	0.95475643	0.157596469	normal	0.760180456	0.403562726	normal	0.247354489	0.298060656	normal	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	K11996|0|nle:100598927|MOCS3; molybdenum cofactor synthesis 3; K11996 adenylyltransferase and sulfurtransferase (A)	Sulfur relay system (ko04122)	[H]	Coenzyme transport and metabolism	ThiF family;; MoeZ/MoeB domain;; Rhodanese-like domain	Molybdopterin-synthase sulfurtransferase {ECO:0000255|HAMAP-Rule:MF_03049} OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	hypothetical protein PANDA_000789 [Ailuropoda melanoleuca]
ENSG00000124222(STX16)	--	26.38524841	2103	24.62522943	1939	22.2118768	1882	24.87051534	2099	26.81202961	2211	27.03807029	2183	0.987042812	-0.033554409	normal	0.977569065	0.167837013	normal	0.970451289	0.205600532	normal	0.606698017	0.11115514	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: membrane (GO:0016020);; 	"K08489|0|hsa:8675|STX16, SYN16; syntaxin 16; K08489 syntaxin 16 (A)"	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain;; Syntaxin	Syntaxin-16 GN=STX16 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-16 isoform 1 [Odobenus rosmarus divergens]
ENSG00000124225(PMEPA1)	--	49.888037	3026	50.343528	3084	46.6793039	2953	221.986785	15129	324.2137	22311	161.724557	10874	0	2.290424018	up	0	2.832850437	up	0	1.871802712	up	9.86E-05	2.392612	up	--	--	--	--	--	--	--	--	Protein TMEPAI GN=PMEPA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: transmembrane prostate androgen-induced protein [Odobenus rosmarus divergens]
ENSG00000124226(RNF114)	--	34.28902996	1342	30.23132221	1168	32.53792407	1262	35.36151378	1398	33.64327035	1196	29.2426336	1143	0.982826986	0.028115888	normal	0.980974282	0.012734264	normal	0.972163705	-0.150987745	normal	0.902702768	-0.035250082	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K15697|8.95888e-159|pps:100979652|RNF114; ring finger protein 114; K15697 RING finger protein 114 (A)	--	--	--	"Drought induced 19 protein (Di19), zinc-binding;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; RING-type zinc-finger"	E3 ubiquitin-protein ligase RNF114 GN=RNF114 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF114 [Felis catus]
ENSG00000124228(DDX27)	--	22.99032626	1492	25.50733279	1697	28.23590803	1809	22.45797858	1444	24.68709584	1505	25.40013894	1600	0.981847179	-0.077927478	normal	0.968517921	-0.19446548	normal	0.971750911	-0.185247165	normal	0.427210027	-0.156472693	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K13181|0|hsa:55661|DDX27, DRS1, Drs1p, PP3241, RHLP, dJ686N3.1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 (EC:3.6.4.13); K13181 ATP-dependent RNA helicase DDX27 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Protein of unknown function (DUF1253)	Probable ATP-dependent RNA helicase DDX27 GN=DDX27 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX27 isoform X2 [Galeopterus variegatus]
ENSG00000124243(BCAS4)	--	16.928946	497	13.37292544	397	11.32936907	434	12.50672312	411	11.4018006	389	9.755114	331	0.888049637	-0.303904715	normal	0.967607846	-0.05060068	normal	0.756810407	-0.39756396	normal	0.302360918	-0.253470689	normal	--	--	--	--	--	--	--	--	Breast carcinoma-amplified sequence 4 GN=BCAS4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: breast carcinoma-amplified sequence 4 [Odobenus rosmarus divergens]
ENSG00000124249(KCNK15)	--	1.851647	49	1.890118	44	2.421693	44	0.291393	8	0.51093	12	0.445588	12	5.49E-05	-2.433678384	down	0.016041791	-1.771856002	normal	0.018542869	-1.759673858	normal	7.52E-05	-2.118053032	down	--	--	--	"K04923|0|hsa:60598|KCNK15, K2p15.1, KCNK11, KCNK14, KT3.3, TASK-5, TASK5, dJ781B1.1; potassium channel, subfamily K, member 15; K04923 potassium channel subfamily K member 15 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel;; Ion transport protein	Potassium channel subfamily K member 15 GN=KCNK15 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 15 [Orycteropus afer afer]
ENSG00000124251(TP53TG5)	--	0.196826	10	0.272183	14	0.0382416	1	0.196769	10	0.267514	13	0.252728	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular tumour antigen p53-inducible 5	TP53-target gene 5 protein GN=TP53TG5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: TP53-target gene 5 protein [Ceratotherium simum simum]
ENSG00000124256(ZBP1)	--	0	0	0	0	0	0	0.02288868	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: double-stranded RNA adenosine deaminase activity (GO:0003726);; 	"K12965|0|hsa:81030|ZBP1, C20orf183, DAI, DLM-1, DLM1; Z-DNA binding protein 1; K12965 Z-DNA binding protein 1 (A)"	Cytosolic DNA-sensing pathway (ko04623)	--	--	Adenosine deaminase z-alpha domain;; RIP homotypic interaction motif	Z-DNA-binding protein 1 GN=ZBP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: Z-DNA-binding protein 1-like [Galeopterus variegatus]
ENSG00000124257(NEURL2)	--	1.30825	23	0.664262	12	0.965167	17	1.2361	22	0.927999	12	1.33794	24	0.987833723	-0.088890349	normal	--	--	--	0.981405458	0.455002051	normal	0.918922313	0.136471199	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	K16782|0|pps:100971061|NEURL2; neuralized E3 ubiquitin protein ligase 2; K16782 neuralized-like protein 2 (A)	--	[T]	Signal transduction mechanisms	Neuralized;; SOCS box	Neuralized-like protein 2 GN=NEURL2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuralized-like protein 2 [Tupaia chinensis] 
ENSG00000124260(MAGEA10)	--	0	0	0	0	0.021538457	0	0.02192029	1	0	0	0.119993738	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 10 GN=MAGEA10 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: melanoma-associated antigen 10-like [Oryctolagus cuniculus]
ENSG00000124275(MTRR)	--	15.63171153	848	13.89189851	722	14.7896047	717	13.20198	703	15.118567	750	14.94294703	788	0.894814151	-0.300772254	normal	0.974970263	0.033396567	normal	0.968750301	0.127674115	normal	0.866737739	-0.050272584	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00597|0|hsa:4552|MTRR, MSR, cblE; 5-methyltetrahydrofolate-homocysteine methyltransferase reductase (EC:1.16.1.8); K00597 methionine synthase reductase [EC:1.16.1.8] (A)"	--	[C]	Energy production and conversion	FAD binding domain;; Flavodoxin;; Oxidoreductase NAD-binding domain	Methionine synthase reductase GN=MTRR OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: methionine synthase reductase [Eptesicus fuscus]
ENSG00000124279(FASTKD3)	--	6.73249	245	6.773469501	238	6.920712036	247	6.555054051	240	8.791006827	308	6.921070572	254	0.96561595	-0.060198165	normal	0.858840781	0.34859044	normal	0.966796097	0.031833808	normal	0.760494905	0.114841246	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; 	--	--	--	--	"FAST kinase-like protein, subdomain 2;; FAST kinase-like protein, subdomain 1;; RAP domain"	FAST kinase domain-containing protein 3 GN=FASTKD3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: FAST kinase domain-containing protein 3 isoform X1 [Equus caballus] 
ENSG00000124299(PEPD)	--	94.78601684	3149	92.96752197	3175	99.01607744	3334	72.31884737	2315	77.76122879	2581	105.675893	3505	0.497313053	-0.474442634	normal	0.92666934	-0.32008357	normal	0.990377637	0.063840653	normal	0.435160942	-0.221014604	normal	[E]	Amino acid transport and metabolism	Molecular Function: aminopeptidase activity (GO:0004177);; Molecular Function: manganese ion binding (GO:0030145);; 	"K14213|0|hsa:5184|PEPD, PROLIDASE; peptidase D (EC:3.4.13.9); K14213 Xaa-Pro dipeptidase [EC:3.4.13.9] (A)"	--	[R]	General function prediction only	"Metallopeptidase family M24;; Aminopeptidase P, N-terminal domain"	Xaa-Pro dipeptidase GN=PEPD OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: xaa-Pro dipeptidase isoform X1 [Mustela putorius furo] 
ENSG00000124302(CHST8)	--	0	0	0	0	0.0252787	0	0	0	0	0	0.025517388	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09672|0|hsa:64377|CHST8, GALNAC4ST1, GalNAc4ST; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8; K09672 carbohydrate 4-sulfotransferase 8 [EC:2.8.2.-] (A)"	--	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Sulfotransferase family	Carbohydrate sulfotransferase 8 GN=CHST8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: carbohydrate sulfotransferase 8 isoform 1 [Equus caballus] 
ENSG00000124313(IQSEC2)	--	39.87174966	1372	37.19757949	1222	40.48066883	1402	29.10509286	1094	23.70571632	1094	29.26393231	1053	0.830506266	-0.357051102	normal	0.965696881	-0.180821451	normal	0.66024945	-0.420746818	normal	0.050319871	-0.323243934	normal	--	--	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K12495|0|hsa:23096|IQSEC2, BRAG1, MRX1; IQ motif and Sec7 domain 2; K12495 IQ motif and SEC7 domain-containing protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain	IQ motif and SEC7 domain-containing protein 2 GN=IQSEC2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: IQ motif and SEC7 domain-containing protein 2 isoform X1 [Physeter catodon]
ENSG00000124333(VAMP7)	--	21.39712616	794	22.51116393	833	23.51153906	850	24.02734423	886	22.401269	829	19.87486129	735	0.970203499	0.127102528	normal	0.976565578	-0.028319415	normal	0.948341713	-0.217593321	normal	0.902758197	-0.03748128	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K08515|3.75334e-144|chx:102189019|VAMP7; vesicle-associated membrane protein 7; K08515 vesicle-associated membrane protein 7 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Regulated-SNARE-like domain	Vesicle-associated membrane protein 7 GN=VAMP7 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein 7 isoform X1 [Capra hircus]
ENSG00000124334(IL9R)	--	0.221185712	9	0.308459039	12	0.27871498	10	0.125828745	5	0.286699709	10	0.122161417	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05073|0|hsa:3581|IL9R, CD129, IL-9R; interleukin 9 receptor; K05073 interleukin 9 receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640)	--	--	--	Interleukin-9 receptor (Precursor) GN=IL9R OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: interleukin-9 receptor-like [Odobenus rosmarus divergens]
ENSG00000124343(XG)	--	0	0	0	0	0	0	0	0	0	0	0.06032544	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CD99 antigen like protein 2	Glycoprotein Xg (Precursor) GN=XG OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: glycoprotein Xg [Galeopterus variegatus]
ENSG00000124356(STAMBP)	--	27.97547739	1158	26.21421626	1064	23.17224716	1190	18.98819247	814	16.45250428	798	18.95311759	899	0.19428489	-0.538509686	normal	0.614125523	-0.435746207	normal	0.683413849	-0.41225518	normal	0.003199403	-0.463123039	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11866|0|hsa:10617|STAMBP, AMSH, MICCAP; STAM binding protein (EC:3.1.2.15); K11866 STAM-binding protein [EC:3.4.19.12] (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	USP8 dimerisation domain;; JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Prokaryotic homologs of the JAB domain	STAM-binding protein GN=STAMBP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: STAM-binding protein isoform X1 [Galeopterus variegatus] 
ENSG00000124357(NAGK)	--	31.58975719	626	34.132396	757	33.469377	739	22.99852721	533	25.32572177	513	30.205728	722	0.921200373	-0.262161128	normal	0.129602648	-0.581340727	normal	0.975258086	-0.041780466	normal	0.277575247	-0.283526696	normal	[G]	Carbohydrate transport and metabolism	--	"K00884|0|hsa:55577|NAGK, GNK, HSA242910; N-acetylglucosamine kinase (EC:2.7.1.59); K00884 N-acetylglucosamine kinase [EC:2.7.1.59] (A)"	Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	BadF/BadG/BcrA/BcrD ATPase family	N-acetyl-D-glucosamine kinase GN=NAGK OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: N-acetyl-D-glucosamine kinase [Camelus bactrianus] 
ENSG00000124370(MCEE)	--	5.035061464	66	3.762121675	55	4.352297049	55	4.54867287	67	4.1402	50	3.213513	43	0.975613275	-0.008930851	normal	0.974246762	-0.154473338	normal	0.962760651	-0.352400592	normal	0.833277129	-0.160238857	normal	[E]	Amino acid transport and metabolism	--	"K05606|4.94803e-120|hsa:84693|MCEE, GLOD2; methylmalonyl CoA epimerase (EC:5.1.99.1); K05606 methylmalonyl-CoA/ethylmalonyl-CoA epimerase [EC:5.1.99.1] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)"	[G]	Carbohydrate transport and metabolism	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain	"Methylmalonyl-CoA epimerase, mitochondrial (Precursor) GN=MCEE OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: methylmalonyl-CoA epimerase, mitochondrial isoform X1 [Equus caballus]"
ENSG00000124374(PAIP2B)	--	0.825475	85	0.66124	69	0.462049	47	0.540173	56	0.482146	49	0.36674	38	0.787225554	-0.618978403	normal	0.911224158	-0.502116356	normal	0.971702697	-0.304052367	normal	0.336096483	-0.514249322	normal	--	--	--	--	--	--	--	Ataxin-2 C-terminal region	Polyadenylate-binding protein-interacting protein 2B GN=PAIP2B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: polyadenylate-binding protein-interacting protein 2B [Orycteropus afer afer]
ENSG00000124383(MPHOSPH10)	--	16.3487	941	16.049	920	16.88598	968	14.315953	837	14.37199	821	12.639115	734	0.956311182	-0.199453796	normal	0.959630519	-0.18535545	normal	0.697452469	-0.406786191	normal	0.158234322	-0.263556117	normal	--	--	Cellular Component: nucleus (GO:0005634);; Cellular Component: small nucleolar ribonucleoprotein complex (GO:0005732);; Biological Process: rRNA processing (GO:0006364);; Cellular Component: Mpp10 complex (GO:0034457);; 	"K14559|0|hsa:10199|MPHOSPH10, CT90, MPP10, MPP10P, PPP1R106; M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein); K14559 U3 small nucleolar RNA-associated protein MPP10 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	Mpp10 protein	U3 small nucleolar ribonucleoprotein protein MPP10 GN=MPHOSPH10 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U3 small nucleolar ribonucleoprotein protein MPP10-like [Ceratotherium simum simum]
ENSG00000124391(IL17C)	--	0.148245	2	0	0	0	0	0	0	0	0	0.0728412	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular region (GO:0005576);; 	"K05491|1.64195e-114|hsa:27189|IL17C, CX2, IL-17C; interleukin 17C; K05491 interleukin 17C (A)"	--	--	--	Interleukin-17	Interleukin-17C (Precursor) GN=IL17C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: interleukin-17C [Mustela putorius furo] 
ENSG00000124406(ATP8A1)	--	0.260557351	33	0.11847161	15	0.15119396	18	0.117300295	15	0.221304755	28	0.14995477	19	0.782817582	-1.09118355	normal	0.940436035	0.817879456	normal	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	"K14802|0|pps:100989463|ATP8A1; ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1; K14802 phospholipid-transporting ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase	Phospholipid-transporting ATPase IA GN=ATP8A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IA isoform X1 [Bos mutus]
ENSG00000124422(USP22)	--	89.110866	8394	89.76967296	8535	83.65879546	7944	97.16112305	9059	106.8795973	10049	87.02297848	8263	0.995236079	0.07914713	normal	0.989442893	0.214127329	normal	0.995306179	0.04849955	normal	0.620454882	0.116576258	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11366|0|hsa:23326|USP22, USP3L; ubiquitin specific peptidase 22 (EC:3.4.19.12); K11366 ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein	Ubiquitin carboxyl-terminal hydrolase 22 GN=USP22 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 22-like [Ochotona princeps]
ENSG00000124429(POF1B)	--	4.397091862	299	6.635961429	444	4.0713272	271	8.796019773	606	8.084672642	549	6.78128393	463	1.63E-05	0.984716455	normal	0.905479731	0.283948778	normal	0.008057081	0.761140537	normal	0.020482539	0.651550374	normal	--	--	--	--	--	--	--	--	Protein POF1B GN=POF1B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein POF1B isoform X1 [Oryctolagus cuniculus]
ENSG00000124440(HIF3A)	--	0	0	0.025033207	1	0	0	0.032025533	1	0	0	0.033607993	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09096|0|pps:100979253|HIF3A; hypoxia inducible factor 3, alpha subunit; K09096 hypoxia-inducible factor 3 alpha (A)"	--	[TK]	Signal transduction mechanisms;; Transcription	PAS domain;; PAS fold;; PAS fold;; Hypoxia-inducible factor-1;; PAS domain;; PAS fold	Hypoxia-inducible factor 3-alpha GN=HIF3A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: hypoxia-inducible factor 3-alpha isoform X1 [Camelus ferus]
ENSG00000124444(ZNF576)	--	11.65101895	319	10.0102889	295	11.83105803	321	9.097706097	269	13.1233863	335	9.403907	285	0.915230436	-0.275336233	normal	0.953912199	0.161243518	normal	0.951234052	-0.179007235	normal	0.797384309	-0.093608594	normal	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger double domain"	Zinc finger protein 576 GN=ZNF576 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 576 isoform X1 [Leptonychotes weddellii]
ENSG00000124459(ZNF45)	--	5.383499247	485	5.77085558	486	5.768761886	497	6.180583665	490	6.06419792	529	6.3268	541	0.971370213	-0.015984883	normal	0.96643091	0.100584798	normal	0.965997293	0.113759439	normal	0.835366533	0.066863686	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7596|ZNF45, KOX5, ZNF13; zinc finger protein 45; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; XPA protein N-terminal;; Zinc-finger of C2H2 type;; Zinc ribbon domain;; TFIIH C1-like domain"	Zinc finger protein 45 GN=ZNF45 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 45 [Galeopterus variegatus]
ENSG00000124466(LYPD3)	--	0.662314	18	0.144617	4	0.777049	21	0.219798	6	0.320288	8	0	0	--	--	--	--	--	--	0.001939059	-3.899780498	down	--	--	--	--	--	--	--	--	--	--	u-PAR/Ly-6 domain	Ly6/PLAUR domain-containing protein 3 (Precursor) GN=LYPD3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ly6/PLAUR domain-containing protein 3 [Tupaia chinensis]
ENSG00000124479(NDP)	--	0.0365032	1	0	0	0	0	0.072354	2	0.0708827	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[WV]	Extracellular structures;; Defense mechanisms	Cystine-knot domain;; DAN domain	Norrin (Precursor) GN=NDP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: norrin [Equus caballus] 
ENSG00000124486(USP9X)	--	38.0759299	6567	40.675629	7093	38.390993	6589	36.91734246	6487	35.65907	6157	36.7324159	6391	0.994439776	-0.048503862	normal	0.984796471	-0.225543272	normal	0.994335513	-0.052297093	normal	0.632646487	-0.110529266	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11840|0|hsa:8239|USP9X, DFFRX, FAF, FAM, MRX99; ubiquitin specific peptidase 9, X-linked (EC:3.4.19.12); K11840 ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Probable ubiquitin carboxyl-terminal hydrolase FAF-X GN=USP9X OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable ubiquitin carboxyl-terminal hydrolase FAF-X isoform X2 [Oryctolagus cuniculus]
ENSG00000124491(F13A1)	--	0	0	0	0	0	0	0.01217478	1	0	0	0.120588988	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein-glutamine gamma-glutamyltransferase activity (GO:0003810);; Biological Process: peptide cross-linking (GO:0018149);; 	"K03917|0|hsa:2162|F13A1, F13A; coagulation factor XIII, A1 polypeptide (EC:2.3.2.13); K03917 coagulation factor XIII A1 polypeptide [EC:2.3.2.13] (A)"	Complement and coagulation cascades (ko04610)	--	--	"Transglutaminase family, C-terminal ig like domain;; Transglutaminase family;; Transglutaminase-like superfamily"	Coagulation factor XIII A chain (Precursor) GN=F13A1 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	hypothetical protein PANDA_003036 [Ailuropoda melanoleuca]
ENSG00000124493(GRM4)	--	0.064628534	3	0.026063935	2	0.020725903	0	0	0	0.020814156	0	0.021259588	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04607|0|hsa:2914|GRM4, GPRC1D, MGLUR4, mGlu4; glutamate receptor, metabotropic 4; K04607 metabotropic glutamate receptor 4 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724);; Taste transduction (ko04742)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Nine Cysteines Domain of family 3 GPCR;; Periplasmic binding protein	Metabotropic glutamate receptor 4 (Precursor) GN=GRM4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: metabotropic glutamate receptor 4 isoform X1 [Orycteropus afer afer]
ENSG00000124496(TRERF1)	--	4.329526398	638	4.246027763	597	4.751931861	683	4.316803981	642	3.467083442	513	4.908022548	734	0.974174363	-0.021763145	normal	0.933251013	-0.239543333	normal	0.971590664	0.095399245	normal	0.902758197	-0.042659684	normal	--	--	--	--	--	[K]	Transcription	"ELM2 domain;; C2H2-type zinc finger;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Transcriptional-regulating factor 1 GN=TRERF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcriptional-regulating factor 1 isoform X2 [Bos taurus] 
ENSG00000124507(PACSIN1)	--	0.064441258	6	0.010523497	1	0.031021638	2	0	0	0.02091916	1	0.03188405	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TUZ]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	"Fes/CIP4, and EFC/F-BAR homology domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain"	Protein kinase C and casein kinase substrate in neurons protein 1 GN=PACSIN1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: protein kinase C and casein kinase substrate in neurons protein 1 [Galeopterus variegatus] 
ENSG00000124508(BTN2A2)	--	4.68879365	304	4.07689884	203	4.261591293	240	7.248705056	347	5.895225001	313	4.681639304	248	0.955307126	0.159278238	normal	0.25022585	0.599633025	normal	0.966541042	0.038773917	normal	0.455714776	0.259413312	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06712|0|hsa:10385|BTN2A2, BT2.2, BTF2, BTN2.2; butyrophilin, subfamily 2, member A2; K06712 butyrophilin (A)"	--	--	--	SPRY-associated domain;; SPRY domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain	Butyrophilin subfamily 2 member A2 (Precursor) GN=BTN2A2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: butyrophilin subfamily 2 member A2-like [Vicugna pacos]
ENSG00000124523(SIRT5)	--	4.849030228	285	5.1558611	247	5.498789	267	4.198197	234	4.380001411	251	6.41835	325	0.893435827	-0.313417345	normal	0.966087628	0.001739202	normal	0.916233519	0.273900283	normal	1	-0.000444538	normal	[K]	Transcription	Molecular Function: NAD+ binding (GO:0070403);; 	K11415|0|pon:100173543|SIRT5; sirtuin 5 (EC:3.5.1.-); K11415 NAD-dependent deacetylase sirtuin 5 [EC:3.5.1.-] (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	Sir2 family;; NAD(P) transhydrogenase beta subunit	"NAD-dependent protein deacylase sirtuin-5, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03160} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: NAD-dependent protein deacylase sirtuin-5, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000124532(MRS2)	--	14.32825916	567	12.96784885	550	12.18790863	535	14.76806287	610	15.53050716	669	13.72861007	568	0.970949146	0.074433769	normal	0.923226996	0.260497721	normal	0.970105438	0.077847008	normal	0.581328673	0.139571939	normal	--	--	--	"K16075|0|hsa:57380|MRS2, HPT, MRS2L; MRS2 magnesium transporter; K16075 magnesium transporter (A)"	--	[P]	Inorganic ion transport and metabolism	--	"Magnesium transporter MRS2 homolog, mitochondrial (Precursor) GN=MRS2 OS=Homo sapiens (Human) PE=1 SV=1"	P	Inorganic ion transport and metabolism	"PREDICTED: magnesium transporter MRS2 homolog, mitochondrial isoform X2 [Camelus ferus]"
ENSG00000124535(WRNIP1)	--	18.97552895	922	17.882469	819	19.7093631	936	20.2400246	953	19.206951	873	18.350188	879	0.978689124	0.016849583	normal	0.975067691	0.07056543	normal	0.974454103	-0.098772097	normal	0.987369772	-0.006292045	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	"K07478|0|hsa:56897|WRNIP1, WHIP, bA420G6.2; Werner helicase interacting protein 1 (EC:3.6.1.3); K07478 putative ATPase (A)"	--	[L]	"Replication, recombination and repair"	"MgsA AAA+ ATPase C terminal;; ATPase family associated with various cellular activities (AAA);; Holliday junction DNA helicase ruvB N-terminus;; AAA domain;; Sigma-54 interaction domain;; AAA domain (dynein-related subfamily);; Protein of unknown function (DUF815);; AAA domain (Cdc48 subfamily);; Magnesium chelatase, subunit ChlI;; Rad17 cell cycle checkpoint protein"	ATPase WRNIP1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: ATPase WRNIP1 isoform X1 [Mustela putorius furo] 
ENSG00000124541(RRP36)	--	34.12262	1165	30.94487	1121	33.75992	1169	33.42988	1179	35.42426	1230	28.01362	1080	0.981300264	-0.013580697	normal	0.976145349	0.112300816	normal	0.974963947	-0.122370312	normal	0.98564369	-0.007225369	normal	--	--	Biological Process: cleavage involved in rRNA processing (GO:0000469);; 	"K14795|1.28546e-120|hsa:88745|RRP36, C6orf153, dJ20C7.4; ribosomal RNA processing 36 homolog (S. cerevisiae); K14795 ribosomal RNA-processing protein 36 (A)"	--	[S]	Function unknown	Domain of unknown function (DUF947)	Ribosomal RNA processing protein 36 homolog GN=RRP36 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ribosomal RNA processing protein 36 homolog [Ceratotherium simum simum]
ENSG00000124562(SNRPC)	--	85.04110358	1002	89.17075161	1062	92.072153	1119	98.274579	1188	92.27455	1070	91.207269	1108	0.955450948	0.214517705	normal	0.979797172	-0.010584512	normal	0.980665089	-0.022513021	normal	0.822849126	0.059345848	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	K11095|4.03958e-38|cmy:102944220|SNRPC; small nuclear ribonucleoprotein polypeptide C; K11095 U1 small nuclear ribonucleoprotein C (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	U1 zinc finger	U1 small nuclear ribonucleoprotein C {ECO:0000255|HAMAP-Rule:MF_03153} OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U1 small nuclear ribonucleoprotein C isoform X1 [Leptonychotes weddellii]
ENSG00000124564(SLC17A3)	--	0.060507673	2	0.09504793	2	0	0	0.214726234	6	0.46231157	9	0.589625198	13	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12300|0|hsa:10786|SLC17A3, NPT4; solute carrier family 17 (organic anion transporter), member 3; K12300 MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Sodium-dependent phosphate transport protein 4 GN=SLC17A3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transport protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000124568(SLC17A1)	--	0	0	0	0	0.04324876	0	0	0	0.126520576	1	0.12878505	3	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12300|0|hsa:6568|SLC17A1, NAPI-1, NPT-1, NPT1; solute carrier family 17 (organic anion transporter), member 1; K12300 MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 1/2/3/4 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Sodium-dependent phosphate transport protein 1 GN=SLC17A1 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transport protein 1 isoform X1 [Oryctolagus cuniculus] 
ENSG00000124570(SERPINB6)	--	56.373789	1521	50.51720264	1400	53.723851	1502	63.70512697	1773	59.425491	1635	49.73331553	1369	0.970046205	0.190162078	normal	0.96563698	0.202234943	normal	0.976054179	-0.141904093	normal	0.697039798	0.089207238	normal	--	--	--	"K13963|0|hsa:5269|SERPINB6, CAP, DFNB91, MSTP057, PI-6, PI6, PTI, SPI3; serpin peptidase inhibitor, clade B (ovalbumin), member 6; K13963 serpin B (A)"	Amoebiasis (ko05146)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B6 GN=SERPINB6 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: serpin B6 [Equus przewalskii] 
ENSG00000124571(XPO5)	--	12.89354	1414	14.142586	1520	14.10661	1532	14.43824	1544	13.69944	1453	11.5812	1245	0.980811257	0.095958572	normal	0.981142119	-0.086375272	normal	0.906114119	-0.307224946	normal	0.676851969	-0.095985659	normal	--	--	--	"K14289|0|hsa:57510|XPO5, exp5; exportin 5; K14289 exportin-5 (A)"	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Exportin 1-like protein	Exportin-5 GN=XPO5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exportin-5 isoform X1 [Equus przewalskii]
ENSG00000124574(ABCC10)	--	5.03276228	400	3.821969744	367	3.436737835	314	3.848532373	358	4.854628029	419	4.4145442	405	0.948792836	-0.190100302	normal	0.953376736	0.169091165	normal	0.832292245	0.35734662	normal	0.737434437	0.10776483	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05674|0|hsa:89845|ABCC10, EST182763, MRP7, SIMRP7; ATP-binding cassette, sub-family C (CFTR/MRP), member 10; K05674 ATP-binding cassette, subfamily C (CFTR/MRP), member 10 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC transporter;; ABC transporter transmembrane region;; RecF/RecN/SMC N terminal domain;; AAA domain;; Miro-like protein;; 50S ribosome-binding GTPase	Multidrug resistance-associated protein 7 GN=ABCC10 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: multidrug resistance-associated protein 7 [Ceratotherium simum simum]
ENSG00000124575(HIST1H1D)	--	1.119202	38	1.609531	28	1.294576	33	1.743037	31	1.763591	20	0.761567	25	0.976828131	-0.310631518	normal	0.97503007	-0.476279324	normal	0.976275123	-0.388322248	normal	0.601492541	-0.403431187	normal	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11275|2.06462e-30|ggo:101138821|histone H1.3-like; K11275 histone H1/5 (A)	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	Histone H1.3 GN=HIST1H1D OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	histone H1.3-like protein [Sus scrofa]
ENSG00000124587(PEX6)	--	8.574443425	553	8.619993969	573	9.963279461	649	10.96157403	705	11.38472066	726	9.730634999	629	0.872322668	0.318725654	normal	0.874296122	0.319257776	normal	0.973233595	-0.053323683	normal	0.38714725	0.193598344	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K13339|0|hsa:5190|PEX6, PAF-2, PAF2, PBD4A, PDB4B, PXAAA1; peroxisomal biogenesis factor 6; K13339 peroxin-6 (A)"	Peroxisome (ko04146)	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATPase family associated with various cellular activities (AAA);; AAA ATPase domain;; Part of AAA domain;; AAA domain;; AAA domain;; NACHT domain;; AAA domain (dynein-related subfamily);; AAA domain;; AAA domain;; AAA domain;; Holliday junction DNA helicase ruvB N-terminus;; RNA helicase;; Magnesium chelatase, subunit ChlI"	Peroxisome assembly factor 2 GN=PEX6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxisome assembly factor 2 [Ceratotherium simum simum]
ENSG00000124588(NQO2)	--	20.95607556	814	23.79652849	948	22.33790535	861	16.87138143	710	16.78146544	643	16.61062303	679	0.943418177	-0.22758162	normal	0.116340353	-0.580363163	normal	0.829612354	-0.350198758	normal	0.024682074	-0.389752773	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; 	"K08071|1.59744e-173|hsa:4835|NQO2, DHQV, DIA6, NMOR2, QR2; NAD(P)H dehydrogenase, quinone 2 (EC:1.10.99.2); K08071 ribosyldihydronicotinamide dehydrogenase (quinone) [EC:1.10.99.2] (A)"	--	--	--	Flavodoxin-like fold;; NADPH-dependent FMN reductase	Ribosyldihydronicotinamide dehydrogenase [quinone] GN=NQO2 OS=Homo sapiens (Human) PE=1 SV=5	C	Energy production and conversion	PREDICTED: ribosyldihydronicotinamide dehydrogenase [quinone] [Ursus maritimus]
ENSG00000124593(RP11-298J23.10)	--	4.07885619	112	5.71928269	138	4.98059778	139	3.22891429	88	3.867689	114	2.596249	84	0.918660066	-0.372967531	normal	0.932915478	-0.293516038	normal	0.303554406	-0.724666152	normal	0.231874146	-0.464770458	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	LIM domain;; PET Domain	Prickle-like protein 4 GN=PRICKLE4 OS=Homo sapiens (Human) PE=2 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: prickle-like protein 4 [Galeopterus variegatus]
ENSG00000124596(OARD1)	--	15.30828149	348	13.213308	285	19.560101	385	15.616374	334	14.2140341	333	17.94937406	344	0.964847816	-0.089667316	normal	0.944245641	0.202140613	normal	0.953683761	-0.170034336	normal	0.94549489	-0.030657043	normal	--	--	--	--	--	--	--	Macro domain	O-acetyl-ADP-ribose deacetylase 1 GN=OARD1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: O-acetyl-ADP-ribose deacetylase 1 [Galeopterus variegatus] 
ENSG00000124602(UNC5CL)	--	0.225502571	8	0.35495454	10	0.116772237	4	1.62084755	43	2.273140544	70	1.194323655	39	0.001586881	2.195644091	up	1.08E-07	2.615224314	up	7.84E-05	2.870637383	up	1.38E-05	2.766078101	up	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	ZU5 domain;; Death domain	UNC5C-like protein GN=UNC5CL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: UNC5C-like protein isoform X3 [Mustela putorius furo] 
ENSG00000124608(AARS2)	--	3.692838	356	4.224994	412	4.201874	417	4.4938229	426	3.582776	332	3.657603	341	0.936569517	0.227246459	normal	0.864195147	-0.331529083	normal	0.896252262	-0.297372392	normal	0.6713481	-0.13053963	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: alanine-tRNA ligase activity (GO:0004813);; Molecular Function: ATP binding (GO:0005524);; Biological Process: alanyl-tRNA aminoacylation (GO:0006419);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	"K01872|0|hsa:57505|AARS2, AARSL, COXPD8, LKENP, MT-ALARS, MTALARS; alanyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.7); K01872 alanyl-tRNA synthetase [EC:6.1.1.7] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class II (A);; Threonyl and Alanyl tRNA synthetase second additional domain	"Alanine--tRNA ligase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03133} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: alanine--tRNA ligase, mitochondrial [Ceratotherium simum simum]"
ENSG00000124610(HIST1H1A)	--	0	0	0	0	0	0	0.130437	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K11275|5.3272e-35|mcc:694975|HIST1H1A; histone cluster 1, H1a; K11275 histone H1/5 (A)"	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	Histone H1.1 GN=HIST1H1A OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.1-like [Bos mutus] 
ENSG00000124613(ZNF391)	--	0.207726571	13	0.145845054	9	0.22515158	13	0.365579525	23	0.35437697	22	0.328872696	20	0.97039189	0.727013391	normal	0.909292967	1.1421424	normal	0.98218455	0.560318009	normal	0.246379473	0.871867382	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; BED zinc finger"	Zinc finger protein 391 GN=ZNF391 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 391 [Tursiops truncatus]
ENSG00000124614(RPS10)	--	966.4362557	8654	854.3764546	7744	882.1266003	8053	898.0260151	8698	1011.677336	9122	897.0755002	8091	0.995760396	-0.023511512	normal	0.988533747	0.214805975	normal	0.995519296	-0.001499472	normal	0.818502798	0.062305205	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Plectin/S10 domain	40S ribosomal protein S10 GN=RPS10 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S10 isoform X1 [Bubalus bubalis]
ENSG00000124615(MOCS1)	--	1.846214711	120	1.656534975	105	2.0300097	128	1.542493789	102	1.372792625	87	1.712895914	101	0.948108512	-0.261658855	normal	0.945205421	-0.288161627	normal	0.920616532	-0.345474006	normal	0.505382915	-0.304643598	normal	[H]	Coenzyme transport and metabolism	"Molecular Function: catalytic activity (GO:0003824);; Biological Process: Mo-molybdopterin cofactor biosynthetic process (GO:0006777);; Cellular Component: molybdopterin synthase complex (GO:0019008);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; Molecular Function: 4 iron, 4 sulfur cluster binding (GO:0051539);; "	K03639|0|mcf:102145915|MOCS1; molybdenum cofactor synthesis 1; K03639 cyclic pyranopterin phosphate synthase [EC:4.1.99.18] (A)	Folate biosynthesis (ko00790);; Sulfur relay system (ko04122)	[H]	Coenzyme transport and metabolism	MoaC family;; Molybdenum Cofactor Synthesis C;; Radical SAM superfamily;; 4Fe-4S single cluster domain;; 4Fe-4S single cluster domain	Cyclic pyranopterin monophosphate synthase accessory protein GN=MOCS1 OS=Homo sapiens (Human) PE=1 SV=3	H	Coenzyme transport and metabolism	PREDICTED: molybdenum cofactor biosynthesis protein 1 isoform X1 [Tupaia chinensis]
ENSG00000124635(HIST1H2BJ)	--	4.59388732	147	4.75884727	156	6.1746331	132	1.933046727	102	2.618015361	79	5.276853	147	0.680435829	-0.551122166	normal	0.00998453	-0.989305953	normal	0.961405239	0.145407508	normal	0.251003868	-0.427707726	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|5.64328e-60|lve:103085965|histone H2B type 1-J-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-J GN=HIST1H2BJ OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2B type 1-J-like [Sorex araneus] 
ENSG00000124641(MED20)	--	7.269003882	295	7.40382936	303	9.744893208	337	11.88418254	432	10.310602	355	9.655532818	357	0.400035426	0.517246044	normal	0.943061358	0.206123446	normal	0.966232191	0.07455893	normal	0.29697076	0.269424383	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	"K13528|1.79112e-157|ptr:462687|MED20, TRFP; mediator complex subunit 20; K13528 mediator of RNA polymerase II transcription subunit 20 (A)"	--	[K]	Transcription	TATA-binding related factor (TRF) of subunit 20 of Mediator complex	Mediator of RNA polymerase II transcription subunit 20 GN=MED20 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 20 [Eptesicus fuscus]
ENSG00000124657(OR2B6)	--	0.107597777	1	0.00211013	0	2.143521	7	9.40E-05	0	0.1321061	1	0.106344434	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:26212|OR2B6, OR2B1, OR2B1P, OR2B5, OR2B6P, OR5-40, OR5-41, OR6-31, dJ408B20.2; olfactory receptor, family 2, subfamily B, member 6; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 2B6 GN=OR2B6 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 2B6-like [Mustela putorius furo] 
ENSG00000124659(TBCC)	--	7.50168	195	8.26841	218	6.55543	174	7.51255	196	7.55834	197	7.20375	189	0.96683905	-0.023269858	normal	0.953655811	-0.166344526	normal	0.962670215	0.110089201	normal	0.955665903	-0.033946517	normal	--	--	Molecular Function: tubulin binding (GO:0015631);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin binding cofactor C	Tubulin-specific chaperone C GN=TBCC OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin-specific chaperone C [Mustela putorius furo] 
ENSG00000124664(SPDEF)	--	0.202001459	7	0.275346332	9	0.030884156	0	1.35450984	47	1.799103	61	0.907856476	32	9.54E-05	2.479789261	up	1.61E-06	2.552437443	up	2.37E-06	4.46593213	up	1.35E-06	3.104584934	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09442|0|pps:100973115|SPDEF; SAM pointed domain containing ETS transcription factor; K09442 SAM pointed domain-containing ETS transcription factor (A)	--	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	SAM pointed domain-containing Ets transcription factor GN=SPDEF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: SAM pointed domain-containing Ets transcription factor isoformX2 [Canis lupus familiaris] 
ENSG00000124678(TCP11)	--	0.1667913	3	0.036315671	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	T-complex protein 11	T-complex protein 11 homolog GN=TCP11 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: T-complex protein 11 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000124688(MAD2L1BP)	--	14.105364	296	12.924659	272	12.435421	262	15.287843	319	14.240017	298	13.525582	285	0.965317854	0.076743231	normal	0.961134446	0.109696311	normal	0.96183429	0.112481008	normal	0.78854852	0.098355245	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of exit from mitosis (GO:0007096);; 	--	--	--	--	Mad1 and Cdc20-bound-Mad2 binding	MAD2L1-binding protein GN=MAD2L1BP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MAD2L1-binding protein [Galeopterus variegatus]
ENSG00000124701(APOBEC2)	--	0.0477634	1	0	0	0	0	0.140967	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	"K18772|1.43198e-145|nle:100591310|APOBEC2; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2; K18772 C->U-editing enzyme APOBEC2 [EC:3.5.4.-] (A)"	--	--	--	APOBEC-like N-terminal domain;; APOBEC-like C-terminal domain	Probable C-	A	RNA processing and modification	PREDICTED: probable C-
ENSG00000124702(KLHDC3)	--	14.14741445	452	18.79821625	610	16.26712665	526	23.56871043	757	22.09639825	701	24.81942403	795	0.009031318	0.711251154	normal	0.956724568	0.178764969	normal	0.105662839	0.586220232	normal	0.005644014	0.483477181	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif"	Kelch domain-containing protein 3 GN=KLHDC3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: kelch domain-containing protein 3 [Ursus maritimus] 
ENSG00000124713(GNMT)	--	0.0549066	1	0.106493	2	0.157091	2	0.0541357	1	0.0533086	0	0.0540727	1	--	--	--	--	--	--	--	--	--	--	--	--	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	K00552|0|ptr:462703|GNMT; glycine N-methyltransferase; K00552 glycine N-methyltransferase [EC:2.1.1.20] (A)	"Glycine, serine and threonine metabolism (ko00260)"	--	--	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Tellurite resistance protein TehB	Glycine N-methyltransferase GN=GNMT OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: glycine N-methyltransferase [Odobenus rosmarus divergens]
ENSG00000124731(TREM1)	--	0.131847421	3	0.065265838	2	0	0	0.708855352	11	0.750889381	14	0.259059061	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K14362|1.03819e-135|pps:100977244|TREM1; triggering receptor expressed on myeloid cells 1; K14362 triggering receptor expressed on myeloid cells 1 (A)	--	--	--	Immunoglobulin V-set domain	Triggering receptor expressed on myeloid cells 1 (Precursor) GN=TREM1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	triggering receptor expressed on myeloid cells 1 precursor [Canis lupus familiaris] 
ENSG00000124733(MEA1)	--	30.11388	591	35.39604	724	35.1291	714	30.33851	613	28.1744	553	29.4237	593	0.973485204	0.021840929	normal	0.703648642	-0.409155627	normal	0.914001294	-0.275542048	normal	0.28783493	-0.227236393	normal	--	--	Biological Process: spermatogenesis (GO:0007283);; 	--	--	--	--	Male enhanced antigen 1 (MEA1)	Male-enhanced antigen 1 GN=MEA1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: male-enhanced antigen 1 isoform X1 [Ursus maritimus]
ENSG00000124743(KLHL31)	--	0.307525	27	0.06893712	6	0.34390887	29	0.205267815	18	0.31952711	24	0.228210697	20	0.972471786	-0.575426977	normal	0.458809524	1.745234311	normal	0.97338355	-0.512023923	normal	1	-0.019472242	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K10467|0|hsa:401265|KLHL31, BKLHD6, KBTBD1, KLHL, bA345L23.2; kelch-like family member 31; K10467 kelch-like protein 31 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; BTB/POZ domain;; Kelch motif;; Kelch motif;; Protein of unknown function (DUF1668)"	Kelch-like protein 31 GN=KLHL31 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 31 [Tupaia chinensis]
ENSG00000124749(COL21A1)	--	1.665327223	157	1.512802481	141	1.05409004	98	1.047017527	99	1.526757395	143	1.400516346	106	0.313650104	-0.687543047	normal	0.966858164	-0.001094913	normal	0.968137303	0.103384846	normal	0.67040182	-0.207905433	normal	--	--	--	"K16629|0|hsa:81578|COL21A1, COLA1L, dJ682J15.1, dJ708F5.1; collagen, type XXI, alpha 1; K16629 collagen, type XXI, alpha (A)"	Protein digestion and absorption (ko04974);; Proteoglycans in cancer (ko05205)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; von Willebrand factor type A domain	Collagen alpha-1(XXI) chain (Precursor) GN=COL21A1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: collagen alpha-1(XXI) chain [Equus caballus] 
ENSG00000124762(CDKN1A)	--	80.31500692	2982	86.45093299	3263	93.78894308	3527	152.4270871	5643	162.1300416	5952	206.6719985	7673	1.32E-05	0.889011569	normal	9.27E-05	0.845454695	normal	1.71E-09	1.112726188	up	3.16E-05	0.959411394	normal	--	--	Molecular Function: cyclin-dependent protein serine/threonine kinase inhibitor activity (GO:0004861);; Cellular Component: nucleus (GO:0005634);; Biological Process: cell cycle arrest (GO:0007050);; 	--	--	[T]	Signal transduction mechanisms	Cyclin-dependent kinase inhibitor	Cyclin-dependent kinase inhibitor 1 GN=CDKN1A OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: cyclin-dependent kinase inhibitor 1 [Vicugna pacos] 
ENSG00000124766(SOX4)	--	21.8977	2052	27.0096	2557	17.4337	1655	40.0244	3779	54.9595	5164	43.7754	4140	5.12E-05	0.849665935	normal	4.94E-07	0.992189183	normal	2.03E-13	1.31372262	up	5.65E-05	1.041135737	up	--	--	--	K09268|1.34142e-132|mcf:102136214|SOX4; SRY (sex determining region Y)-box 4; K09268 transcription factor SOX4/11/12 (SOX group C) (A)	--	[K]	Transcription	HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-4 GN=SOX4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor SOX-4 [Ceratotherium simum simum]
ENSG00000124767(GLO1)	--	111.741	3209	105.508	3021	121.607	3438	107.495	3128	98.5411	2826	85.5755	2473	0.989722617	-0.067682716	normal	0.986568992	-0.117630378	normal	0.46521622	-0.483346889	normal	0.217738062	-0.219899432	normal	[E]	Amino acid transport and metabolism	--	"K01759|3.37574e-135|hsa:2739|GLO1, GLOD1, GLYI, HEL-S-74; glyoxalase I (EC:4.4.1.5); K01759 lactoylglutathione lyase [EC:4.4.1.5] (A)"	Pyruvate metabolism (ko00620)	[G]	Carbohydrate transport and metabolism	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	Lactoylglutathione lyase GN=GLO1 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: lactoylglutathione lyase [Camelus dromedarius]
ENSG00000124772(CPNE5)	--	0.040259005	2	0	0	0	0	0.020154035	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-5 GN=CPNE5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: copine-5 [Trichechus manatus latirostris]
ENSG00000124782(RREB1)	--	5.11478212	810	4.836058913	871	5.192978679	750	8.33254249	779	4.631288023	791	7.214471418	897	0.973645528	-0.086962619	normal	0.964403631	-0.160129691	normal	0.934626548	0.249465418	normal	1	0.000217548	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Ras-responsive element-binding protein 1 GN=RREB1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: ras-responsive element-binding protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000124783(SSR1)	--	49.6794335	2394	50.40452628	2443	48.84844646	2316	61.48375208	2913	51.03402734	2591	57.94881635	2856	0.962208553	0.252103427	normal	0.98763138	0.063390489	normal	0.940526256	0.293896171	normal	0.259429379	0.203573764	normal	--	--	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; 	K13249|6.68613e-164|mcf:101926002|uncharacterized LOC101926002; K13249 translocon-associated protein subunit alpha (A)	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Translocon-associated protein (TRAP), alpha subunit"	Translocon-associated protein subunit alpha (Precursor) GN=SSR1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: translocon-associated protein subunit alpha isoform X1 [Camelus dromedarius]
ENSG00000124784(RIOK1)	--	4.707866078	277	5.016470005	286	4.818141926	281	4.314822309	255	5.13984754	302	5.01003856	287	0.956823896	-0.149357195	normal	0.965352803	0.056814481	normal	0.967425783	0.022071627	normal	0.968673048	-0.020792131	normal	[TD]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning"	--	"K07178|0|hsa:83732|RIOK1, AD034, RRP10, bA288G3.1; RIO kinase 1 (EC:2.7.11.1); K07178 RIO kinase 1 [EC:2.7.11.1] (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[TD]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning"	RIO1 family;; Protein kinase domain;; Phosphotransferase enzyme family	Serine/threonine-protein kinase RIO1 GN=RIOK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase RIO1 isoform X1 [Galeopterus variegatus]
ENSG00000124785(NRN1)	--	0.141221065	4	0.207201308	6	0.081505341	1	1.18986727	34	0.986851492	28	2.172652362	59	0.001282808	2.656378447	up	0.131726971	1.955271743	normal	6.30E-12	4.584463901	up	9.05E-05	3.43784642	up	--	--	--	--	--	--	--	Neuritin protein family	Neuritin (Precursor) GN=NRN1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: neuritin isoform X2 [Mustela putorius furo]
ENSG00000124786(SLC35B3)	--	8.799116279	301	9.817660961	320	8.577317559	297	9.564655733	318	7.483495298	257	10.00260021	340	0.966952347	0.048191685	normal	0.868874325	-0.335954513	normal	0.949629854	0.185895087	normal	0.958484282	-0.025896056	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Biological Process: transmembrane transport (GO:0055085);; 	"K15277|0|hsa:51000|SLC35B3, C6orf196, PAPST2; solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3; K15277 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3 (A)"	--	[G]	Carbohydrate transport and metabolism	UAA transporter family	Adenosine 3'-phospho 5'-phosphosulfate transporter 2 GN=SLC35B3 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: adenosine 3'-phospho 5'-phosphosulfate transporter 2 isoform X1 [Ailuropoda melanoleuca]
ENSG00000124787(RPP40)	--	8.282074	153	12.106827	192	9.685444294	185	10.67804962	202	9.267271	160	9.538033	148	0.874090659	0.366777331	normal	0.924476985	-0.282023773	normal	0.90651159	-0.327222516	normal	0.880861602	-0.07761424	normal	--	--	--	K14530|0|pon:100431252|RPP40; ribonuclease P/MRP 40kDa subunit; K14530 ribonucleases P/MRP protein subunit RPP40 [EC:3.1.26.5] (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	--	--	Ribonuclease P 40kDa (Rpp40) subunit	Ribonuclease P protein subunit p40 GN=RPP40 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: ribonuclease P protein subunit p40 isoform X1 [Pteropus alecto] 
ENSG00000124788(ATXN1)	--	2.640901696	481	2.520654539	460	2.207345154	409	2.042963732	380	1.938109484	360	1.944428642	364	0.802666957	-0.369538109	normal	0.801423177	-0.373671011	normal	0.952686001	-0.175764516	normal	0.175796042	-0.311787656	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Ataxin-1 and HBP1 module (AXH);; Capicua transcriptional repressor modulator	Ataxin-1 GN=ATXN1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ataxin-1 [Equus caballus]
ENSG00000124789(NUP153)	--	21.16570052	2170	21.69661855	2202	20.82435169	2105	18.598271	1918	20.44583092	2107	16.70969148	1734	0.969773116	-0.208767228	normal	0.985324475	-0.084991034	normal	0.934306693	-0.287779605	normal	0.302955257	-0.190982278	normal	--	--	--	"K14296|0|hsa:9972|NUP153, HNUP153, N153; nucleoporin 153kDa; K14296 nuclear pore complex protein Nup153 (A)"	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Nucleoporin Nup153-like;; Zn-finger in Ran binding protein and others;; Retro-transposon transporting motif	Nuclear pore complex protein Nup153 GN=NUP153 OS=Homo sapiens (Human) PE=1 SV=2	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: LOW QUALITY PROTEIN: nuclear pore complex protein Nup153 [Camelus dromedarius]
ENSG00000124795(DEK)	--	61.93213655	3503	68.76909495	3853	69.88765065	3896	70.3165209	4030	59.56245754	3364	58.13611245	3269	0.985042048	0.171286505	normal	0.977855398	-0.217139744	normal	0.966019051	-0.261324853	normal	0.66095326	-0.099362547	normal	--	--	--	K17046|6.66816e-149|ggo:101128103|DEK; protein DEK isoform 1; K17046 protein DEK (A)	--	[B]	Chromatin structure and dynamics	DEK C terminal domain;; SAP domain	Protein DEK GN=DEK OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: protein DEK isoform X1 [Panthera tigris altaica] 
ENSG00000124802(EEF1E1)	--	42.876481	484	42.62089226	514	48.48821915	541	37.89241012	432	42.3526982	476	37.09224985	421	0.948815505	-0.194155148	normal	0.962286339	-0.131830159	normal	0.800145626	-0.368927562	normal	0.323280127	-0.232722705	normal	--	--	--	K15439|3.88281e-111|ggo:101125082|EEF1E1; eukaryotic translation elongation factor 1 epsilon-1; K15439 eukaryotic translation elongation factor 1 epsilon-1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain"	Eukaryotic translation elongation factor 1 epsilon-1 GN=EEF1E1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation elongation factor 1 epsilon-1 [Equus caballus] 
ENSG00000124813(RUNX2)	--	2.353996816	202	2.039949116	149	2.803220466	220	3.333378513	252	2.917090478	218	2.276180661	164	0.915737889	0.286283481	normal	0.603145434	0.523175312	normal	0.790296567	-0.42867366	normal	0.784932947	0.129035138	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09278|0|mcf:102124310|RUNX2; runt-related transcription factor 2; K09278 runt-related transcription factor 2 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Runt domain	Runt-related transcription factor 2 GN=RUNX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: runt-related transcription factor 2 isoform X5 [Myotis brandtii]
ENSG00000124827(GCM2)	--	0.0208123	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	GCM motif protein	Chorion-specific transcription factor GCMb GN=GCM2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: chorion-specific transcription factor GCMb [Pteropus alecto] 
ENSG00000124831(LRRFIP1)	--	32.58610536	3007	32.76320973	3027	34.2062032	3050	25.65960213	2274	21.68074758	1947	20.398912	1861	0.672426684	-0.433669117	normal	0.018881835	-0.657649128	normal	0.002764148	-0.720560477	normal	2.10E-05	-0.60060053	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	Double stranded RNA binding protein (DUF2051)	Leucine-rich repeat flightless-interacting protein 1 GN=LRRFIP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: leucine-rich repeat flightless-interacting protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000124839(RAB17)	--	0.165169826	4	0.091338074	3	0	0	0.118749087	1	0	0	0.05086426	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07909|4.66965e-143|hsa:64284|RAB17; RAB17, member RAS oncogene family; K07909 Ras-related protein Rab-17 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-17 GN=RAB17 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-17 [Galeopterus variegatus]
ENSG00000124875(CXCL6)	--	0.0484653	1	0	0	0.0960494	1	2.345232596	49	3.180009594	66	3.29362	51	2.27E-09	4.295430265	up	1.09E-14	5.469909739	up	5.03E-10	4.379906607	up	9.67E-17	6.355767184	up	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K05506|5.21464e-50|hsa:6372|CXCL6, CKA-3, GCP-2, GCP2, SCYB6; chemokine (C-X-C motif) ligand 6; K05506 C-X-C motif chemokine 5/6 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Pertussis (ko05133);; Rheumatoid arthritis (ko05323)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	"Small-inducible cytokine B6, N-processed variant 3 (Precursor) GN=CXCL6 OS=Homo sapiens (Human) PE=1 SV=4"	T	Signal transduction mechanisms	PREDICTED: alveolar macrophage chemotactic factor-like [Oryctolagus cuniculus]
ENSG00000124882(EREG)	--	67.0451	4299	45.6842	2906	63.4301	3964	60.5165	3923	43.539	2799	30.6195	1971	0.986797784	-0.162815094	normal	0.988333779	-0.075509731	normal	1.14E-07	-1.015759648	down	0.427757343	-0.384591487	normal	--	--	--	"K09784|4.97875e-100|hsa:2069|EREG, ER; epiregulin; K09784 epiregulin (A)"	ErbB signaling pathway (ko04012)	--	--	EGF-like domain	Epiregulin (Precursor) GN=EREG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: proepiregulin [Orcinus orca] 
ENSG00000124920(MYRF)	--	4.636017665	579	3.251882137	403	4.051398272	511	16.5686602	2038	21.22330842	2635	15.33530353	1920	0	1.78200283	up	0	2.68299492	up	0	1.898307755	up	6.49E-15	2.121667002	up	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[S]	Function unknown	Myelin gene regulatory factor C-terminal domain 2;; NDT80 / PhoG like DNA-binding  family;; Myelin gene regulatory factor -C-terminal domain 1;; Chaperone of endosialidase	"Myelin regulatory factor, C-terminal GN=MYRF OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: myelin regulatory factor [Tupaia chinensis]
ENSG00000124942(AHNAK)	--	64.991799	29457	61.44699501	29582	70.43468834	33297	67.6147613	31825	51.66326363	22034	62.824917	29974	0.998339286	0.080713691	normal	0.900092324	-0.446388184	normal	0.997526632	-0.159964357	normal	0.545373684	-0.16070108	normal	--	--	--	--	--	--	--	Bacterial protein of unknown function (DUF945);; PDZ domain (Also known as DHR or GLGF)	Neuroblast differentiation-associated protein AHNAK GN=AHNAK OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: neuroblast differentiation-associated protein AHNAK isoform X2 [Felis catus]
ENSG00000125037(EMC3)	--	32.974308	1035	38.86544	1201	24.987799	912	32.85133	1083	28.78532	1008	36.90838	1120	0.979773293	0.034520116	normal	0.927478112	-0.273790201	normal	0.913818044	0.287670398	normal	0.985612711	0.007080223	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Integral membrane protein DUF106	ER membrane protein complex subunit 3 GN=EMC3 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	ER membrane protein complex subunit 3 [Bos taurus] 
ENSG00000125046(SSUH2)	--	0.068962422	2	0.135713815	4	0.784912689	4	0.03435049	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Protein SSUH2 homolog GN=SSUH2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein SSUH2 homolog [Galeopterus variegatus]
ENSG00000125084(WNT1)	--	0.110992999	2	0	0	0	0	0.118086	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K03209|0|tup:102499190|WNT1; wingless-type MMTV integration site family, member 1; K03209 wingless-type MMTV integration site family, member 1 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Proto-oncogene Wnt-1 (Precursor) GN=WNT1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: proto-oncogene Wnt-1 [Tupaia chinensis] 
ENSG00000125089(SH3TC1)	--	2.602054375	193	2.180855525	153	2.7792843	204	1.784339602	158	2.07246967	175	2.822875006	237	0.909547042	-0.316716413	normal	0.954989409	0.170817125	normal	0.946183712	0.206604287	normal	0.962333677	0.031905184	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; SH3 domain	SH3 domain and tetratricopeptide repeat-containing protein 1 GN=SH3TC1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SH3 domain and tetratricopeptide repeat-containing protein 1 [Galeopterus variegatus]
ENSG00000125107(CNOT1)	--	57.73880968	6749	65.97532969	7361	55.59589403	7171	63.16714231	6860	51.53227764	6805	68.16521334	7814	0.994877285	-0.007295793	normal	0.992550069	-0.134704375	normal	0.993693278	0.115572141	normal	0.984925516	-0.007442421	normal	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	--	"K12604|0|mcf:102120215|CNOT1; CCR4-NOT transcription complex, subunit 1; K12604 CCR4-NOT transcription complex subunit 1 (A)"	RNA degradation (ko03018)	[K]	Transcription	"CCR4-Not complex component, Not1;; Domain of unknown function (DUF3819)"	CCR4-NOT transcription complex subunit 1 GN=CNOT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 1 isoform 1 [Ceratotherium simum simum] 
ENSG00000125122(LRRC29)	--	1.490635324	39	1.553839944	52	1.2218389	32	0.71588339	17	0.787127447	19	0.592928579	17	0.586362609	-1.157824133	normal	0.066103945	-1.403715849	normal	0.910482554	-0.863972674	normal	0.027217724	-1.23637794	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10275|0|mcc:698911|LRRC29; leucine rich repeat containing 29; K10275 F-box and leucine-rich repeat protein 9 (A)	--	[R]	General function prediction only	Leucine Rich Repeat;; Leucine Rich repeats (2 copies);; Leucine Rich repeat;; Leucine rich repeat;; F-box-like;; F-box domain	Leucine-rich repeat-containing protein 29 GN=LRRC29 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	Leucine-rich repeat-containing protein 29 [Myotis davidii]
ENSG00000125124(BBS2)	--	14.74465618	773	13.05049492	705	14.170262	753	14.94933909	789	16.22978	753	16.15820604	834	0.976662303	-0.001272873	normal	0.973013132	0.07344759	normal	0.967876273	0.138841021	normal	0.800852526	0.069849478	normal	--	--	--	"K16747|0|hsa:583|BBS2, BBS; Bardet-Biedl syndrome 2; K16747 Bardet-Biedl syndrome 2 protein (A)"	--	--	--	"Ciliary BBSome complex subunit 2, C-terminal;; Ciliary BBSome complex subunit 2, N-terminal;; Ciliary BBSome complex subunit 2, middle region;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Bardet-Biedl syndrome 2 protein GN=BBS2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Bardet-Biedl syndrome 2 protein [Galeopterus variegatus]
ENSG00000125148(MT2A)	--	306.399856	2462	181.024421	1495	279.597984	2340	1266.32568	10472	897.75853	7289	648.55042	5272	0	2.057125535	up	0	2.263002557	up	1.99E-10	1.163035967	up	0.000701162	1.848077348	up	--	--	--	--	--	--	--	Metallothionein	--	--	--	--
ENSG00000125149(C16orf70)	--	11.455884	480	10.06868921	438	11.06689299	445	11.09293031	500	11.18789755	509	10.18599403	475	0.971184061	0.027973695	normal	0.948409752	0.194684225	normal	0.967639844	0.085549295	normal	0.731740104	0.10135242	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised protein family (UPF0183)	UPF0183 protein C16orf70 GN=C16orf70 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0183 protein C16orf70 homolog [Mustela putorius furo] 
ENSG00000125166(GOT2)	--	101.013672	4339	93.34599586	4020	104.0890161	4458	107.4640131	4626	107.2831083	4569	94.93017809	4080	0.992256162	0.061549308	normal	0.986971606	0.163198767	normal	0.98907709	-0.136070639	normal	0.917098815	0.029248241	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K14455|0|ptr:467989|GOT2; glutamic-oxaloacetic transaminase 2, mitochondrial; K14455 aspartate aminotransferase, mitochondrial [EC:2.6.1.1] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Cysteine and methionine metabolism (ko00270);; Arginine and proline metabolism (ko00330);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Phenylalanine, tyrosine and tryptophan biosynthesis (ko00400);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230);; Fat digestion and absorption (ko04975)"	[E]	Amino acid transport and metabolism	Aminotransferase class I and II	"Aspartate aminotransferase, mitochondrial (Precursor) GN=GOT2 OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: aspartate aminotransferase, mitochondrial isoform X1 [Sorex araneus]"
ENSG00000125170(DOK4)	--	8.722529084	400	7.30398028	365	7.612354592	313	22.18564252	956	24.88621989	1199	25.27924273	1117	9.76E-10	1.223047849	up	0	1.690347833	up	0	1.822126912	up	1.33E-20	1.580830449	up	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	--	--	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type);; PH domain	Docking protein 4 GN=DOK4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: docking protein 4 isoform 3 [Dasypus novemcinctus]
ENSG00000125245(GPR18)	--	0.094948098	2	0	0	0.114846	0	0	0	0.0736897	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08410|0|ptr:738311|GPR18; G protein-coupled receptor 18; K08410 G protein-coupled receptor 18 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	N-arachidonyl glycine receptor GN=GPR18 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: N-arachidonyl glycine receptor [Galeopterus variegatus]
ENSG00000125246(CLYBL)	--	2.926566086	57	3.597784161	55	2.053854517	39	2.744665147	57	3.9106897	66	2.14462338	41	0.977420637	-0.030023001	normal	0.966724071	0.235685616	normal	0.981235146	0.061531129	normal	0.910030233	0.096627003	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; 	"K11390|0|hsa:171425|CLYBL, CLB; citrate lyase beta like; K11390 citrate lyase subunit beta-like protein [EC:4.1.-.-] (A)"	--	--	--	HpcH/HpaI aldolase/citrate lyase family	"Citrate lyase subunit beta-like protein, mitochondrial (Precursor) GN=CLYBL OS=Homo sapiens (Human) PE=2 SV=2"	C	Energy production and conversion	"PREDICTED: citrate lyase subunit beta-like protein, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000125247(TMTC4)	--	8.768279212	439	9.135703547	453	7.451540528	408	9.761100238	484	7.318861456	371	7.791725383	419	0.965160364	0.109588488	normal	0.885632416	-0.308378702	normal	0.969677149	0.029979993	normal	0.890153671	-0.051056758	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Domain of unknown function (DUF1736);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Transmembrane and TPR repeat-containing protein 4 GN=TMTC4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane and TPR repeat-containing protein 4 isoform X1 [Galeopterus variegatus]
ENSG00000125249(RAP2A)	--	5.16228	410	6.12013	489	5.45363	428	5.69895	460	5.78918	461	4.81095	383	0.961261189	0.134700972	normal	0.965148125	-0.106156082	normal	0.954752611	-0.167930243	normal	0.898038535	-0.047029671	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07837|1.17713e-112|pon:100172918|RAP2A; RAP2A, member of RAS oncogene family; K07837 Ras-related protein Rap-2A (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein Rap-2a (Precursor) GN=RAP2A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Rap-2a [Camelus bactrianus]
ENSG00000125257(ABCC4)	--	24.851269	2583	27.207353	2792	25.92990246	2663	15.85073475	1683	16.584663	1725	17.198794	1836	0.018566455	-0.648362933	normal	0.004139499	-0.715630938	normal	0.182414578	-0.544403266	normal	5.21E-06	-0.637128597	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05673|0|ptr:452625|ABCC4; ATP-binding cassette, sub-family C (CFTR/MRP), member 4; K05673 ATP-binding cassette, subfamily C (CFTR/MRP), member 4 (A)"	ABC transporters (ko02010);; cAMP signaling pathway (ko04024);; Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"ABC transporter transmembrane region;; ABC transporter;; RecF/RecN/SMC N terminal domain;; AAA domain;; AAA ATPase domain;; Miro-like protein;; 50S ribosome-binding GTPase;; P-loop containing region of AAA domain;; Protein of unknown function, DUF258;; Dynamin family"	Multidrug resistance-associated protein 4 GN=ABCC4 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: multidrug resistance-associated protein 4 isoform 1 [Trichechus manatus latirostris]
ENSG00000125266(EFNB2)	--	1.97392	166	1.521861	122	2.274141	184	5.733787	481	3.99122	330	2.065775	171	1.16E-11	1.495520953	up	1.24E-08	1.403161241	up	0.962523782	-0.113036927	normal	0.179658141	1.033374832	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K05463|0|ptr:735430|EFNB2; ephrin-B2; K05463 ephrin-B (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Ephrin	Ephrin-B2 (Precursor) GN=EFNB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ephrin-B2 [Orycteropus afer afer]
ENSG00000125285(SOX21)	--	0.97913	39	0.643577	26	0.386579	15	0.445099	18	0.695612	28	0.394064	16	0.679191623	-1.082086237	normal	0.984819813	0.080950942	normal	--	--	--	0.679564134	-0.39001886	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09267|3.30619e-99|ssc:100517115|SOX21; SRY (sex determining region Y)-box 21; K09267 transcription factor SOX1/3/14/21 (SOX group B) (A)	--	[K]	Transcription	HMG (high mobility group) box;; HMG-box domain;; SOX transcription factor	Transcription factor SOX-21 GN=SOX21 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor SOX-21 isoform X1 [Chrysochloris asiatica]
ENSG00000125304(TM9SF2)	--	57.24497941	2563	56.18832043	2435	54.68773971	2323	63.550228	2921	60.47178608	2750	67.844888	3023	0.982786791	0.157708016	normal	0.982269003	0.153993253	normal	0.850619253	0.371487798	normal	0.196989562	0.226746164	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17086|0|ggo:101153802|TM9SF2; transmembrane 9 superfamily member 2; K17086 transmembrane 9 superfamily member 2/4 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endomembrane protein 70	Transmembrane 9 superfamily member 2 (Precursor) GN=TM9SF2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane 9 superfamily member 2 [Camelus ferus]
ENSG00000125319(C17orf53)	--	4.893904	252	4.86083735	245	6.642853	341	5.054933	258	3.893036334	193	4.709814	244	0.967195498	0.003096411	normal	0.858274204	-0.363075806	normal	0.553961557	-0.488608114	normal	0.358436068	-0.290833117	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4539)	Uncharacterized protein C17orf53 GN=C17orf53 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C17orf53 homolog [Galeopterus variegatus]
ENSG00000125337(KIF25)	--	0.2328871	5	0.991413386	4	0.044758989	0	0.118867505	3	0.117220272	2	0.277829604	7	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K18627|0|ggo:101145813|KIF25; LOW QUALITY PROTEIN: kinesin-like protein KIF25; K18627 kinesin family member 25 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF25 GN=KIF25 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF25 [Equus przewalskii] 
ENSG00000125347(IRF1)	--	13.05710247	492	12.77155787	533	13.19668566	517	17.42268038	708	12.09849169	528	18.7095628	721	0.398193047	0.492969245	normal	0.971145039	-0.034924601	normal	0.484070673	0.470373271	normal	0.136082092	0.322573947	normal	--	--	Molecular Function: regulatory region DNA binding (GO:0000975);; 	"K09444|0|hsa:3659|IRF1, IRF-1, MAR; interferon regulatory factor 1; K09444 interferon regulatory factor 1 (A)"	Prolactin signaling pathway (ko04917);; Pertussis (ko05133);; Hepatitis C (ko05160)	--	--	Interferon regulatory factor transcription factor	Interferon regulatory factor 1 GN=IRF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: interferon regulatory factor 1 isoform 3 [Dasypus novemcinctus] 
ENSG00000125351(UPF3B)	--	8.702285696	518	10.0387288	612	9.975486292	582	10.40081478	622	10.54180806	615	10.20752321	610	0.936883024	0.232500227	normal	0.973212366	-0.014336461	normal	0.972139314	0.059348006	normal	0.755656779	0.08827497	normal	--	--	--	K14328|0|nle:100587257|UPF3B; UPF3 regulator of nonsense transcripts homolog B (yeast); K14328 regulator of nonsense transcripts 3 (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Smg-4/UPF3 family	Regulator of nonsense transcripts 3B GN=UPF3B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: regulator of nonsense transcripts 3B isoform 1 [Ceratotherium simum simum]
ENSG00000125352(RNF113A)	--	7.34892	194	8.03558	219	8.60626	235	10.6164	285	9.48734	250	10.4829	278	0.512942081	0.520652572	normal	0.952678717	0.168481162	normal	0.936729058	0.232754064	normal	0.296189311	0.306152041	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K13127|0|hsa:7737|RNF113A, Cwc24, RNF113, ZNF183; ring finger protein 113A; K13127 RING finger protein 113A (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 113A GN=RNF113A OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 113A [Galeopterus variegatus]
ENSG00000125354(SEPT6)	--	8.663175641	614	6.985948098	524	9.126393546	557	6.8871649	503	7.378021203	528	6.2921554	450	0.873002391	-0.317632614	normal	0.971540301	-0.010425467	normal	0.876717717	-0.315090102	normal	0.35191935	-0.216178925	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K16939|0|pps:100988668|SEPT6; septin 6; K16939 septin 6/8/11 (A)	Bacterial invasion of epithelial cells (ko05100)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Septin	Septin-6 GN=SEPT6 OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: septin-6 isoform 2 [Trichechus manatus latirostris]
ENSG00000125355(TMEM255A)	--	1.02862745	55	0.508331118	22	0.964360172	39	0.842389382	45	1.025551061	48	0.682086183	37	0.967068815	-0.310724351	normal	0.541901289	1.053961457	normal	0.981661479	-0.081014624	normal	0.875136822	0.142920751	normal	--	--	--	--	--	--	--	FAM70 protein	Transmembrane protein 255A GN=TMEM255A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 255A isoform X1 [Loxodonta africana] 
ENSG00000125356(NDUFA1)	--	76.8369	703	88.87	828	74.4573	698	98.6768	916	80.6684	742	100.249	927	0.829540342	0.350318279	normal	0.959393894	-0.179292003	normal	0.716665066	0.400295875	normal	0.357021837	0.192320542	normal	--	--	--	"K03945|1.84491e-45|hsa:4694|NDUFA1, CI-MWFE, MWFE, ZNF183; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (EC:1.6.99.3); K03945 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 1 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	--	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 GN=NDUFA1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 [Galeopterus variegatus]
ENSG00000125375(ATP5S)	--	3.446351012	336	4.970768001	384	3.551172	323	3.508372	310	4.070670017	351	3.177825	282	0.957588615	-0.146328388	normal	0.95662916	-0.15044187	normal	0.945085304	-0.203111851	normal	0.583066321	-0.166998575	normal	--	--	--	"K07554|1.95263e-87|ptr:467450|ATP5S; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B); K07554 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit s (A)"	--	[S]	Function unknown	--	"ATP synthase subunit s, mitochondrial (Precursor) GN=ATP5S OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: ATP synthase subunit s, mitochondrial [Pteropus alecto]"
ENSG00000125378(BMP4)	--	16.5007671	539	11.68156759	389	14.37008529	442	8.565027912	291	13.22897833	417	11.0535953	337	0.000134708	-0.916482923	normal	0.966125834	0.078555678	normal	0.754242236	-0.398024657	normal	0.157559097	-0.411324227	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04662|0|hsa:652|BMP4, BMP2B, BMP2B1, MCOPS6, OFC11, ZYME; bone morphogenetic protein 4; K04662 bone morphogenetic protein 2/4 (A)"	Hedgehog signaling pathway (ko04340);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Thyroid hormone signaling pathway (ko04919);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Bone morphogenetic protein 4 (Precursor) GN=BMP4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein 4 isoform X1 [Camelus ferus] 
ENSG00000125384(PTGER2)	--	1.23366115	41	1.0141257	32	0.999644382	33	0.713668264	24	1.308933426	43	0.624120277	21	0.894940486	-0.765489079	normal	0.967066416	0.388934343	normal	0.956734764	-0.624228722	normal	0.723241561	-0.289761884	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04259|0|hsa:5732|PTGER2, EP2; prostaglandin E receptor 2 (subtype EP2), 53kDa; K04259 prostaglandin E receptor 2 (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Inflammatory mediator regulation of TRP channels (ko04750);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srx;; Serpentine type 7TM GPCR chemoreceptor Srsx	Prostaglandin E2 receptor EP2 subtype GN=PTGER2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	prostaglandin E2 receptor EP2 subtype [Oryctolagus cuniculus] 
ENSG00000125386(FAM193A)	--	4.268390436	521	4.898698774	585	4.406741035	550	4.347008682	529	5.063730361	622	5.51529194	680	0.972195531	-0.008822095	normal	0.971132489	0.066883707	normal	0.895456441	0.297075764	normal	0.637294429	0.124480509	normal	--	--	--	--	--	--	--	--	Protein FAM193A GN=FAM193A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM193A [Equus caballus]
ENSG00000125388(GRK4)	--	0.781610192	28	0.427595142	16	0.426009632	15	0.875306796	32	0.487865836	17	0.797544735	29	0.98401804	0.153909333	normal	--	--	--	0.925366393	0.878144059	normal	0.660075049	0.380454665	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08291|0|pps:100972921|GRK4; G protein-coupled receptor kinase 4; K08291 G protein-coupled receptor kinase [EC:2.7.11.16] (A)	Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Regulator of G protein signaling domain;; Kinase-like	G protein-coupled receptor kinase 4 GN=GRK4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: G protein-coupled receptor kinase 4 [Galeopterus variegatus]
ENSG00000125398(SOX9)	--	3.831865	258	3.44604	221	3.858734833	264	4.09194816	277	4.517867779	309	3.07622693	211	0.965183554	0.071272989	normal	0.667769932	0.459463778	normal	0.885111658	-0.329470694	normal	0.84450821	0.07960389	normal	--	--	--	K18435|0|mcc:574208|SOX9; SRY (sex determining region Y)-box 9; K18435 transcription factor SOX9 (SOX group E) (A)	cAMP signaling pathway (ko04024)	[K]	Transcription	Sox developmental protein N terminal;; HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-9 GN=SOX9 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor SOX-9 [Ceratotherium simum simum]
ENSG00000125409(TEKT3)	--	0.030287581	1	0	0	0.029846666	0	0.190648214	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K18630|0|hsa:64518|TEKT3; tektin 3; K18630 tektin-3 (A)	--	[Z]	Cytoskeleton	Tektin family	Tektin-3 GN=TEKT3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tektin-3 [Loxodonta africana]
ENSG00000125430(HS3ST3B1)	--	0.37065755	31	0.414775	29	0.128718211	10	0.7659232	62	1.39580599	117	1.393887	106	0.514677404	0.935795622	normal	1.02E-07	1.936815521	up	1.98E-14	3.215566566	up	0.000292004	2.00442256	up	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K07809|0|hsa:9953|HS3ST3B1, 3-OST-3B, 3OST3B1, h3-OST-3B; heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1 (EC:2.8.2.30); K07809 [heparan sulfate]-glucosamine 3-sulfotransferase 3 [EC:2.8.2.30] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase domain	Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 GN=HS3ST3B1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan sulfate glucosamine 3-O-sulfotransferase 3B1 [Equus caballus]
ENSG00000125434(SLC25A35)	--	11.85230551	413	10.94388206	387	10.98549646	398	3.950928708	139	5.087535957	179	5.443242479	197	1.92E-12	-1.591160996	down	3.99E-06	-1.127158279	down	4.23E-05	-1.017255729	down	1.25E-09	-1.238099585	down	--	--	--	"K15117|0|pps:100975997|SLC25A35; solute carrier family 25, member 35; K15117 solute carrier family 25, member 34/35 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 35 GN=SLC25A35 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 35 isoform X1 [Galeopterus variegatus]
ENSG00000125445(MRPS7)	--	58.834264	1506	62.8597396	1608	68.128863	1712	66.19038	1674	63.189248	1595	65.93434289	1674	0.979612469	0.121627768	normal	0.984022771	-0.033106278	normal	0.984828219	-0.040638312	normal	0.968742065	0.013509694	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02992|5.552e-158|hsa:51081|MRPS7, MRP-S, MRP-S7, RP-S7, RPMS7, S7mt, bMRP27a; mitochondrial ribosomal protein S7; K02992 small subunit ribosomal protein S7 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S7p/S5e	"28S ribosomal protein S7, mitochondrial (Precursor) GN=MRPS7 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S7, mitochondrial [Vicugna pacos]"
ENSG00000125447(GGA3)	--	11.02227716	874	9.302448467	796	9.927446761	849	10.315879	867	10.91747095	840	12.01405421	985	0.977228114	-0.042358785	normal	0.975415756	0.0560906	normal	0.955095759	0.205727226	normal	0.778219434	0.075046117	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K12404|0|pps:100994809|GGA3; golgi-associated, gamma adaptin ear containing, ARF binding protein 3; K12404 ADP-ribosylation factor-binding protein GGA (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	VHS domain;; GAT domain;; Adaptin C-terminal domain	ADP-ribosylation factor-binding protein GGA3 GN=GGA3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-binding protein GGA3 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000125449(ARMC7)	--	10.76600521	375	9.85327528	348	13.08086633	427	10.72744815	364	13.511686	453	12.9850617	416	0.966627389	-0.073478815	normal	0.82849222	0.357631561	normal	0.969305847	-0.045779712	normal	0.815844107	0.080137781	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Armadillo/beta-catenin-like repeat	Armadillo repeat-containing protein 7 GN=ARMC7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing protein 7 [Orcinus orca]
ENSG00000125450(NUP85)	--	36.8502785	1423	37.97783942	1403	40.34768606	1485	34.84732225	1322	37.3827653	1426	31.45589844	1206	0.975986708	-0.136892348	normal	0.98302855	0.002030244	normal	0.903984087	-0.308175551	normal	0.478812107	-0.146009433	normal	--	--	Molecular Function: identical protein binding (GO:0042802);; 	"K14304|0|hsa:79902|NUP85, FROUNT, Nup75; nucleoporin 85kDa; K14304 nuclear pore complex protein Nup85 (A)"	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Nup85 Nucleoporin	Nuclear pore complex protein Nup85 GN=NUP85 OS=Homo sapiens (Human) PE=1 SV=1	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup85 isoform 1 [Ceratotherium simum simum]
ENSG00000125454(SLC25A19)	--	9.801798524	231	10.7452478	216	12.87067879	283	9.583101122	233	7.700500314	192	10.85124161	214	0.96689032	-0.01827414	normal	0.949365023	-0.189940076	normal	0.783476156	-0.408961147	normal	0.530077875	-0.2131607	normal	--	--	--	"K15108|0|hsa:60386|SLC25A19, DNC, MCPHA, MUP1, THMD3, THMD4, TPC; solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19; K15108 solute carrier family 25 (mitochondrial thiamine pyrophosphate transporter), member 19 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial thiamine pyrophosphate carrier GN=SLC25A19 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial thiamine pyrophosphate carrier 1 isoform X6 [Tupaia chinensis]
ENSG00000125457(MIF4GD)	--	35.237501	634	25.5645834	524	31.45206319	589	27.66608894	507	30.52046684	577	32.01979884	613	0.824352553	-0.352372088	normal	0.965465689	0.117255381	normal	0.972725132	0.049204156	normal	0.83842244	-0.062419821	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	MIF4G domain	MIF4G domain-containing protein GN=MIF4GD OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: MIF4G domain-containing protein isoform X1 [Elephantulus edwardii]
ENSG00000125458(NT5C)	--	49.64723	746	47.521641	753	48.183829	784	39.505914	623	43.512859	664	37.077216	582	0.902553335	-0.290120794	normal	0.951333806	-0.202459833	normal	0.601247308	-0.437143523	normal	0.103774148	-0.309921619	normal	[S]	Function unknown	Molecular Function: 5'-nucleotidase activity (GO:0008253);; Biological Process: deoxyribonucleotide catabolic process (GO:0009264);; 	"K01081|5.10486e-145|ptr:736760|NT5C; 5', 3'-nucleotidase, cytosolic; K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	--	--	"5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)"	"5'(3')-deoxyribonucleotidase, cytosolic type GN=NT5C OS=Homo sapiens (Human) PE=1 SV=2"	F	Nucleotide transport and metabolism	"PREDICTED: 5'(3')-deoxyribonucleotidase, cytosolic type [Camelus bactrianus]"
ENSG00000125459(MSTO1)	--	15.998594	632	15.59811912	549	14.114705	552	15.83774586	634	16.52143941	623	15.184785	647	0.973959454	-0.026210364	normal	0.959250033	0.160584006	normal	0.94296266	0.220248118	normal	0.664648599	0.114537005	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; 	--	--	[Z]	Cytoskeleton	"Misato Segment II tubulin-like domain;; Tubulin domain;; Tubulin/FtsZ family, GTPase domain"	Protein misato homolog 1 GN=MSTO1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: protein misato homolog 1 isoform X1 [Galeopterus variegatus]
ENSG00000125462(C1orf61)	--	0.27200654	2	0	0	0	0	0.480259196	4	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein CROC-4 GN=C1orf61 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000125482(TTF1)	--	6.229238	407	6.038776	420	7.202948	465	6.344552	440	7.185828	454	6.098251	410	0.967107312	0.081347088	normal	0.965866772	0.090562729	normal	0.950057253	-0.189242339	normal	0.987504809	-0.007816778	normal	--	--	--	"K15225|0|pps:100973791|TTF1; transcription termination factor, RNA polymerase I; K15225 transcription termination factor 1 (A)"	Thyroid hormone synthesis (ko04918)	[K]	Transcription	Myb-like DNA-binding domain;; Myb-like DNA-binding domain	Transcription termination factor 1 GN=TTF1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription termination factor 1 isoform X1 [Galeopterus variegatus]
ENSG00000125484(GTF3C4)	--	13.3685962	2047	13.1084	2016	14.22322512	2128	14.26429712	2155	15.31181554	2343	11.601825	1754	0.986844518	0.043312819	normal	0.973767195	0.195298763	normal	0.935286141	-0.286915887	normal	0.985385816	-0.007447653	normal	--	--	--	"K11310|0|pps:100975244|GTF3C4; general transcription factor IIIC, polypeptide 4, 90kDa; K11310 general transcription factor 3C polypeptide 4 [EC:2.3.1.48] (A)"	--	--	--	Transcription factor IIIC subunit delta N-term;; Putative zinc-finger of transcription factor IIIC complex	General transcription factor 3C polypeptide 4 GN=GTF3C4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: general transcription factor 3C polypeptide 4 isoform 1 [Odobenus rosmarus divergens]
ENSG00000125485(DDX31)	--	8.722765263	568	8.732043053	600	9.07508901	587	9.242581	595	10.88182002	691	10.332035	701	0.972743787	0.036071143	normal	0.955727404	0.181869232	normal	0.931578773	0.247179057	normal	0.51194448	0.158455194	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14806|0|hsa:64794|DDX31, PPP1R25; DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 (EC:3.6.4.13); K14806 ATP-dependent RNA helicase DDX31/DBP7 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Domain of unknown function (DUF4217)	Probable ATP-dependent RNA helicase DDX31 GN=DDX31 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 [Ceratotherium simum simum]
ENSG00000125492(BARHL1)	--	0.087517724	3	0	0	0.055506131	1	0.056469124	1	0.055957	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09360|0|ptr:744250|BARHL1; BarH-like homeobox 1; K09360 BarH-like (A)	--	[R]	General function prediction only	Homeobox domain	BarH-like 1 homeobox protein GN=BARHL1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: BarH-like homeobox 1 [Canis lupus familiaris] 
ENSG00000125503(PPP1R12C)	--	26.11074789	1376	25.82785431	1441	29.33368762	1578	29.54614696	1600	29.50674655	1563	27.02559889	1490	0.969020404	0.186565856	normal	0.980657252	0.09572441	normal	0.981629753	-0.090986567	normal	0.810489609	0.061100268	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: protein kinase binding (GO:0019901);; 	"K17457|0|hsa:54776|PPP1R12C, LENG3, MBS85, p84, p85; protein phosphatase 1, regulatory subunit 12C; K17457 protein phosphatase 1 regulatory subunit 12C (A)"	Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Proteoglycans in cancer (ko05205)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Protein phosphatase 1 regulatory subunit 12C OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: protein phosphatase 1 regulatory subunit 12C [Orcinus orca]
ENSG00000125505(MBOAT7)	--	101.9346163	4331	84.13492804	3605	93.55232602	4060	122.1136072	4761	128.8760367	5163	105.6119741	4200	0.991076019	0.105696423	normal	0.483643575	0.496608846	normal	0.992078397	0.040603288	normal	0.241300805	0.214198041	normal	--	--	--	K13516|0|ptr:100613350|MBOAT7; membrane bound O-acyltransferase domain containing 7; K13516 lysophospholipid acyltransferase 7 [EC:2.3.1.-] (A)	Glycerophospholipid metabolism (ko00564)	[S]	Function unknown	"MBOAT, membrane-bound O-acyltransferase family"	Lysophospholipid acyltransferase 7 GN=MBOAT7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: lysophospholipid acyltransferase 7 [Galeopterus variegatus]
ENSG00000125510(OPRL1)	--	2.441233013	144	1.334183646	78	1.458921606	88	1.005492497	59	0.779988217	44	1.019644955	60	0.000145587	-1.295782427	down	0.496274803	-0.825788543	normal	0.84663178	-0.549330582	normal	0.073771623	-0.94893082	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04216|0|hsa:4987|OPRL1, KOR-3, NOCIR, OOR, ORL1; opiate receptor-like 1; K04216 nociceptin receptor (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srx	Nociceptin receptor GN=OPRL1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: nociceptin receptor isoform X1 [Canis lupus familiaris] 
ENSG00000125520(SLC2A4RG)	--	82.77191381	2532	74.86426751	2362	77.7565398	2457	73.63148345	2236	71.9995361	2212	66.86281928	1977	0.972320754	-0.210053727	normal	0.984134667	-0.116007367	normal	0.911031472	-0.321655264	normal	0.225800461	-0.215751812	normal	--	--	--	--	--	--	--	--	SLC2A4 regulator GN=SLC2A4RG OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: SLC2A4 regulator [Leptonychotes weddellii]
ENSG00000125531(FNDC11)	--	0.242626165	14	0.217148153	13	0.245388929	14	0.0344219	2	0.0504708	2	0.084937292	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C20orf195 GN=C20orf195 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C20orf195 homolog isoform X1 [Bubalus bubalis] 
ENSG00000125534(PPDPF)	--	177.68176	1832	151.0158	1590	161.82885	1746	230.45346	2422	216.31763	2254	175.54029	1852	0.833630886	0.371675256	normal	0.457824127	0.481647654	normal	0.984189099	0.076674607	normal	0.066610275	0.315142427	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: cell differentiation (GO:0030154);; 	--	--	--	--	Differentiation and proliferation regulator	Pancreatic progenitor cell differentiation and proliferation factor GN=PPDPF OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: pancreatic progenitor cell differentiation and proliferation factor [Eptesicus fuscus]
ENSG00000125538(IL1B)	--	0.240130932	7	0.0345703	1	0.238627458	6	0.563616844	14	0.7028216	20	0.37559075	11	--	--	--	0.027843911	3.083875749	normal	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Molecular Function: interleukin-1 receptor binding (GO:0005149);; Cellular Component: extracellular space (GO:0005615);; Biological Process: inflammatory response (GO:0006954);; Biological Process: immune response (GO:0006955);; 	"K04519|0|hsa:3553|IL1B, IL-1, IL1-BETA, IL1F2; interleukin 1, beta; K04519 interleukin 1 beta (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; Cytosolic DNA-sensing pathway (ko04623);; Hematopoietic cell lineage (ko04640);; TNF signaling pathway (ko04668);; Inflammatory mediator regulation of TRP channels (ko04750);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Type I diabetes mellitus (ko04940);; Alzheimer's disease (ko05010);; Prion diseases (ko05020);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Malaria (ko05144);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323);; Graft-versus-host disease (ko05332)	--	--	Interleukin-1 / 18;; Interleukin-1 propeptide	Interleukin-1 beta (Precursor) GN=IL1B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	interleukin-1 beta precursor [Oryctolagus cuniculus] 
ENSG00000125551(PLGLB2)	--	0	0	0	0	0	0	0	0	0	0	0.061502	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PAN domain	Plasminogen-like protein B (Precursor) GN=PLGLB2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: plasminogen [Galeopterus variegatus]
ENSG00000125571(IL37)	--	0.149339202	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular space (GO:0005615);; Biological Process: inflammatory response (GO:0006954);; Biological Process: immune response (GO:0006955);; 	"K05485|5.71449e-150|hsa:27178|IL37, FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H, IL-1H4, IL-1RP1, IL-37, IL1F7, IL1H4, IL1RP1; interleukin 37; K05485 interleukin 1 family, member 7 (zeta) (A)"	--	--	--	Interleukin-1 / 18	Interleukin-37 (Precursor) GN=IL37 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: interleukin-37 [Equus przewalskii]
ENSG00000125611(CHCHD5)	--	47.573416	443	41.874394	391	39.2309302	367	30.0952353	279	26.0984953	235	26.289778	244	0.03064659	-0.694807983	normal	0.01605059	-0.752139456	normal	0.204641987	-0.594166384	normal	0.001074617	-0.685822742	normal	--	--	--	--	--	--	--	CHCH domain	Coiled-coil-helix-coiled-coil-helix domain-containing protein 5 GN=CHCHD5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil-helix-coiled-coil-helix domain-containing protein 5 [Mustela putorius furo] 
ENSG00000125618(PAX8)	--	0.4190663	24	0.29609186	21	0.353071747	24	0.47397422	33	0.330300296	25	0.395394047	20	0.976403831	0.406342587	normal	0.985088018	0.215852711	normal	0.985791277	-0.253785575	normal	0.890790288	0.154279974	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09293|0|hsa:7849|PAX8; paired box 8; K09293 paired box protein 8 (A)	Thyroid hormone synthesis (ko04918);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Thyroid cancer (ko05216)	[K]	Transcription	'Paired box' domain;; Paired-box protein 2 C terminal	Paired box protein Pax-8 GN=PAX8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: paired box protein Pax-8 [Panthera tigris altaica]
ENSG00000125629(INSIG2)	--	11.988733	418	12.827041	461	13.17508	458	9.356625	335	6.124264	211	8.513636	296	0.841229685	-0.348738791	normal	9.25E-07	-1.143260717	down	0.083312361	-0.635410909	normal	0.000586804	-0.688847874	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Insulin-induced protein (INSIG)	Insulin-induced gene 2 protein GN=INSIG2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: insulin-induced gene 2 protein [Mustela putorius furo] 
ENSG00000125630(POLR1B)	--	13.40770322	1216	14.17905013	1100	14.12514203	1260	11.39597932	868	10.25139473	872	9.922109972	812	0.267045816	-0.51643211	normal	0.8299263	-0.355978988	normal	0.026189336	-0.641196982	normal	0.000940814	-0.50791184	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K03002|0|pps:100968021|POLR1B; polymerase (RNA) I polypeptide B, 128kDa; K03002 DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020)	[K]	Transcription	"RNA polymerase Rpb2, domain 6;; RNA polymerase beta subunit;; RNA polymerase Rpb2, domain 3;; RNA polymerase Rpb2, domain 7;; RNA polymerase I, Rpa2 specific domain;; RNA polymerase Rpb2, domain 2;; RNA polymerase Rpb2, domain 5"	DNA-directed RNA polymerase I subunit RPA2 GN=POLR1B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase I subunit RPA2 isoform X1 [Physeter catodon]
ENSG00000125633(CCDC93)	--	6.079703606	886	6.496676	949	7.196250193	1039	6.199688685	903	5.897082443	854	6.331130848	920	0.978245633	-0.003407122	normal	0.963032828	-0.173307276	normal	0.962480309	-0.183497307	normal	0.588074224	-0.123388167	normal	--	--	--	--	--	[S]	Function unknown	Coiled-coil domain-containing protein (DUF2037)	Coiled-coil domain-containing protein 93 GN=CCDC93 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 93 isoform X3 [Canis lupus familiaris]
ENSG00000125637(PSD4)	--	1.077380642	183	1.1987736	223	1.1465987	202	1.013164684	176	1.007864396	155	1.412699776	242	0.964526346	-0.086361043	normal	0.538645873	-0.541769356	normal	0.932414935	0.250643778	normal	0.81005779	-0.105856172	normal	--	--	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K12494|0|hsa:23550|PSD4, EFA6B, TIC; pleckstrin and Sec7 domain containing 4; K12494 PH and SEC7 domain-containing protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; Pleckstrin homology domain;; PH domain	PH and SEC7 domain-containing protein 4 GN=PSD4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PH and SEC7 domain-containing protein 4 [Ceratotherium simum simum]
ENSG00000125648(SLC25A23)	--	15.07155984	1033	15.56826921	980	15.6249433	1051	16.22551883	1104	16.00871203	1036	18.9495983	1331	0.978735069	0.064974169	normal	0.977883204	0.058655753	normal	0.870691065	0.33203098	normal	0.441741201	0.159360684	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K14684|0|hsa:79085|SLC25A23, APC2, MCSC2, SCaMC-3; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23; K14684 solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41 (A)"	--	[F]	Nucleotide transport and metabolism	Mitochondrial carrier protein;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Calcium-binding mitochondrial carrier protein SCaMC-3 GN=SLC25A23 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-3 [Camelus dromedarius]
ENSG00000125650(PSPN)	--	0.538864	37	0.359659	25	0.795422	55	0.71835	49	1.15037	78	0.793768	55	0.967203549	0.361351488	normal	0.00106437	1.563904979	up	0.977629683	-0.008069561	normal	0.253357537	0.617927105	normal	--	--	--	--	--	--	--	--	Persephin (Precursor) GN=PSPN OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: persephin [Dasypus novemcinctus]
ENSG00000125651(GTF2F1)	--	31.28193649	1801	27.66959534	1714	32.47000274	1843	27.79111426	1683	30.98630536	1876	29.73664993	1750	0.980147972	-0.128481848	normal	0.981872943	0.108774405	normal	0.983868866	-0.082922754	normal	0.900709545	-0.034182577	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; Biological Process: positive regulation of transcription elongation from RNA polymerase II promoter (GO:0032968);; 	"K03138|0|mcf:102128395|GTF2F1; general transcription factor IIF, polypeptide 1, 74kDa; K03138 transcription initiation factor TFIIF subunit alpha (A)"	Basal transcription factors (ko03022)	[K]	Transcription	"Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)"	General transcription factor IIF subunit 1 GN=GTF2F1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: general transcription factor IIF subunit 1 [Bubalus bubalis]
ENSG00000125652(ALKBH7)	--	27.154438	399	20.50378	354	22.34344	335	19.08297	296	19.713287	305	22.10485966	361	0.604766217	-0.459560606	normal	0.932795503	-0.235282642	normal	0.964201964	0.099115195	normal	0.48846016	-0.198350286	normal	--	--	--	"K10769|3.22335e-127|ptr:740313|ALKBH7; alkB, alkylation repair homolog 7 (E. coli); K10769 alkylated DNA repair protein alkB homolog 7 [EC:1.14.11.-] (A)"	--	[S]	Function unknown	2OG-Fe(II) oxygenase superfamily	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial (Precursor) GN=ALKBH7 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial [Galeopterus variegatus]"
ENSG00000125656(CLPP)	--	40.36987049	676	39.31023253	668	40.18339143	689	43.4716013	704	39.12718863	638	43.28372732	672	0.974905797	0.02765832	normal	0.97061207	-0.087515479	normal	0.974343152	-0.044235875	normal	0.913344327	-0.034866453	normal	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	--	"K01358|0|hsa:8192|CLPP, DFNB81, PRLTS3; caseinolytic mitochondrial matrix peptidase proteolytic subunit (EC:3.4.21.92); K01358 ATP-dependent Clp protease, protease subunit [EC:3.4.21.92] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Clp protease	"ATP-dependent Clp protease proteolytic subunit, mitochondrial (Precursor) GN=CLPP OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: ATP-dependent Clp protease proteolytic subunit, mitochondrial [Ailuropoda melanoleuca]"
ENSG00000125657(TNFSF9)	--	8.92213	203	9.9927	230	8.33453	193	26.8001	618	25.0872	573	44.9927	1040	6.08E-14	1.568152832	up	3.41E-09	1.289920597	up	0	2.412493464	up	0.001372399	1.813604408	up	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	"K05472|2.08081e-122|hsa:8744|TNFSF9, 4-1BB-L, CD137L; tumor necrosis factor (ligand) superfamily, member 9; K05472 tumor necrosis factor ligand superfamily member 9 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNF(Tumour Necrosis Factor) family	Tumor necrosis factor ligand superfamily member 9 GN=TNFSF9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tumor necrosis factor ligand superfamily member 9 [Galeopterus variegatus]
ENSG00000125675(GRIA3)	--	0.010948946	1	0	0	0	0	0.019514838	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05199|0|ptr:465842|GRIA3; glutamate receptor, ionotropic, AMPA 3; K05199 glutamate receptor 3 (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033);; Transcriptional misregulation in cancer (ko05202)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Receptor family ligand binding region;; Ligated ion channel L-glutamate- and glycine-binding site;; Bacterial extracellular solute-binding proteins, family 3"	Glutamate receptor 3 (Precursor) GN=GRIA3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: glutamate receptor 3 isoform X2 [Orycteropus afer afer]
ENSG00000125676(THOC2)	--	19.99373846	2284	16.24880791	2082	17.13436247	2134	17.81728445	2394	19.69021122	2446	16.90354757	2236	0.987937345	0.037003924	normal	0.971148831	0.210886332	normal	0.98680123	0.059027702	normal	0.645650682	0.101111807	normal	--	--	--	K12879|0|ptr:465844|THOC2; THO complex 2; K12879 THO complex subunit 2 (A)	RNA transport (ko03013);; Spliceosome (ko03040)	[K]	Transcription	Transcription factor/nuclear export subunit protein 2;; Transcription- and export-related complex subunit	THO complex subunit 2 GN=THOC2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: THO complex subunit 2 isoform X2 [Camelus ferus]
ENSG00000125686(MED1)	--	18.87008865	2931	18.98362753	2877	19.07301131	2870	17.86687739	2755	17.76847142	2775	19.40608289	2974	0.98641358	-0.120107955	normal	0.988323535	-0.073464684	normal	0.989651138	0.043040189	normal	0.845389714	-0.050202342	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	"K15144|0|ptr:454629|MED1, PPARBP; mediator complex subunit 1; K15144 mediator of RNA polymerase II transcription subunit 1 (A)"	Thyroid hormone signaling pathway (ko04919)	--	--	Mediator of RNA polymerase II transcription subunit 1	Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 1 isoform X1 [Leptonychotes weddellii]
ENSG00000125691(RPL23)	--	1302.27663	10775	1294.66776	10963	1326.70614	11184	1624.965111	13981	1501.140254	12605	1457.03345	12301	0.962001537	0.344904144	normal	0.993376688	0.179903759	normal	0.995314304	0.129031253	normal	0.280338684	0.218682508	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02894|1.3956e-88|xtr:496667|rpl23; ribosomal protein L23; K02894 large subunit ribosomal protein L23e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L14p/L23e	60S ribosomal protein L23 GN=RPL23 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	60S ribosomal protein L23 [Bos taurus] 
ENSG00000125703(ATG4C)	--	5.5829891	222	6.635436337	248	5.936359864	258	6.0690147	226	5.6528068	239	6.0933541	244	0.966978657	-0.005034634	normal	0.963733405	-0.074294527	normal	0.963932677	-0.088249365	normal	0.895327936	-0.058949129	normal	--	--	--	"K08342|0|ptr:456903|ATG4C; autophagy related 4C, cysteine peptidase; K08342 cysteine protease ATG4 [EC:3.4.22.-] (A)"	Regulation of autophagy (ko04140)	[ZU]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	Peptidase family C54	Cysteine protease ATG4C GN=ATG4C OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cysteine protease ATG4C isoform X1 [Ursus maritimus] 
ENSG00000125726(CD70)	--	11.31854993	146	9.999056817	140	11.60650364	160	51.05523172	715	51.2042605	705	67.79664276	977	0	2.249329779	up	0	2.298498167	up	0	2.590699816	up	3.82E-14	2.406056672	up	--	--	--	K05470|5.03555e-103|pps:100993608|CD70; CD70 molecule; K05470 tumor necrosis factor ligand superfamily member 7 (A)	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNF(Tumour Necrosis Factor) family	CD70 antigen GN=CD70 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: CD70 antigen [Ceratotherium simum simum]
ENSG00000125730(C3)	--	26.73770351	3272	13.78760726	1691	19.6635	2426	100.336	12254	130.9630021	15974	120.911	14861	0	1.873688582	up	0	3.217208009	up	0	2.605839061	up	3.53E-27	2.523416614	up	--	--	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	"K03990|0|hsa:718|C3, AHUS5, ARMD9, ASP, C3a, C3b, CPAMD1, HEL-S-62p; complement component 3 (EC:3.4.21.43); K03990 complement component 3 (A)"	Phagosome (ko04145);; Complement and coagulation cascades (ko04610);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Herpes simplex infection (ko05168);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; A-macroglobulin receptor;; Alpha-2-macroglobulin family;; UNC-6/NTR/C345C module;; Alpha-2-macroglobulin family N-terminal region;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region;; Anaphylotoxin-like domain	Complement C3c alpha' chain fragment 2 (Precursor) GN=C3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: complement C3-like [Equus caballus]
ENSG00000125731(SH2D3A)	--	4.774227434	195	5.140618	216	6.559154061	215	6.166486026	229	5.301249924	215	5.46407908	220	0.948253655	0.199588933	normal	0.965533044	-0.027925244	normal	0.966763249	0.024703643	normal	0.892446898	0.063750755	normal	--	--	--	--	--	--	--	SH2 domain;; RasGEF domain	SH2 domain-containing protein 3A GN=SH2D3A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH2 domain-containing protein 3A [Ceratotherium simum simum]
ENSG00000125733(TRIP10)	--	29.02693355	1394	28.1514692	1287	31.00995887	1494	24.80932141	1181	27.07005857	1254	22.95008272	1104	0.9334297	-0.269730409	normal	0.980676475	-0.058831227	normal	0.572907369	-0.444206282	normal	0.136384604	-0.259557867	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K07196|0|hsa:9322|TRIP10, CIP4, HSTP, STOT, STP, TRIP-10; thyroid hormone receptor interactor 10; K07196 thyroid hormone receptor interactor 10 (A)"	Insulin signaling pathway (ko04910)	[Z]	Cytoskeleton	"Fes/CIP4, and EFC/F-BAR homology domain;; SH3 domain;; Bacterial SH3 domain"	Cdc42-interacting protein 4 GN=TRIP10 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: cdc42-interacting protein 4 isoform X2 [Galeopterus variegatus]
ENSG00000125734(GPR108)	--	19.73560704	689	17.577798	607	17.830561	657	21.0412012	743	24.696842	849	23.125886	810	0.973020752	0.077858756	normal	0.522577614	0.461664798	normal	0.901518593	0.293128383	normal	0.151538471	0.277711535	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[T]	Signal transduction mechanisms	Lung seven transmembrane receptor	Protein GPR108 (Precursor) GN=GPR108 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: protein GPR108 isoform X2 [Felis catus]
ENSG00000125735(TNFSF14)	--	0.225705092	46	0.336848698	21	0.190205565	36	2.9960734	404	2.671137324	377	3.947383279	589	0	3.062449208	up	0	4.050891499	up	0	3.968418211	up	4.21E-14	3.713665411	up	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	"K05477|1.12071e-146|hsa:8740|TNFSF14, CD258, HVEML, LIGHT, LTg, TR2; tumor necrosis factor (ligand) superfamily, member 14; K05477 tumor necrosis factor ligand superfamily member 14 (A)"	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Herpes simplex infection (ko05168)	--	--	TNF(Tumour Necrosis Factor) family	"Tumor necrosis factor ligand superfamily member 14, soluble form GN=TNFSF14 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor ligand superfamily member 14 isoform X1 [Galeopterus variegatus]
ENSG00000125740(FOSB)	--	0.3271313	13	0.1295495	9	0.2399416	6	0.283517	13	0.25082	17	0.1445631	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09029|4.12929e-155|pps:100989480|FOSB; FBJ murine osteosarcoma viral oncogene homolog B; K09029 protein FosB (A)	Osteoclast differentiation (ko04380);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Protein fosB GN=FOSB OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein fosB isoform X1 [Galeopterus variegatus]
ENSG00000125741(OPA3)	--	12.11335656	1338	15.65715158	1638	13.63109534	1390	11.22798753	1083	11.48560824	1131	10.63922518	1236	0.865812796	-0.335448032	normal	0.160178223	-0.55514238	normal	0.968866496	-0.177492668	normal	0.023699853	-0.360669974	normal	--	--	--	--	--	[R]	General function prediction only	Optic atrophy 3 protein (OPA3)	Optic atrophy 3 protein GN=OPA3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	hypothetical protein PANDA_018531 [Ailuropoda melanoleuca]
ENSG00000125743(SNRPD2)	--	378.5259171	3799	380.8622915	3968	366.0990344	3959	417.8472702	4362	421.6402619	4120	375.2989087	3834	0.986184207	0.168474173	normal	0.991805394	0.032793488	normal	0.991485771	-0.054555995	normal	0.851263961	0.049273369	normal	[K]	Transcription	--	K11096|4.36977e-60|nve:NEMVE_v1g247177|hypothetical protein; K11096 small nuclear ribonucleoprotein D2 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	Small nuclear ribonucleoprotein Sm D2 GN=SNRPD2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: small nuclear ribonucleoprotein Sm D2 [Panthera tigris altaica]
ENSG00000125744(RTN2)	--	11.52540147	301	9.873078873	230	11.1872895	278	6.811303	180	11.12848196	252	6.811440275	174	0.021861684	-0.767473129	normal	0.960828917	0.109674237	normal	0.107521745	-0.679572957	normal	0.109359314	-0.437774228	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Reticulon	Reticulon-2 GN=RTN2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: reticulon-2 isoform X1 [Eptesicus fuscus]
ENSG00000125746(EML2)	--	21.2401749	726	13.00600441	550	17.63357098	657	15.79215694	370	8.231379022	324	13.0107621	507	4.57E-06	-1.000251676	down	0.00389463	-0.782028431	normal	0.769216496	-0.381197317	normal	0.005840148	-0.706776933	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K18595|0|hsa:24139|EML2, ELP70, EMAP-2, EMAP2; echinoderm microtubule associated protein like 2; K18595 echinoderm microtubule-associated protein-like 1/2 (A)"	--	[S]	Function unknown	"HELP motif;; WD domain, G-beta repeat"	Echinoderm microtubule-associated protein-like 2 GN=EML2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: echinoderm microtubule associated protein like 2 isoform X4 [Canis lupus familiaris]
ENSG00000125753(VASP)	--	77.16181711	2587	58.74730479	2143	64.3255094	2417	82.08420545	2572	69.04609561	2393	53.56350425	1758	0.988734354	-0.039198327	normal	0.982259195	0.137670019	normal	0.504749557	-0.467229565	normal	0.73341311	-0.11039864	normal	--	--	--	K06274|8.13068e-97|nle:100597154|uncharacterized LOC100597154; K06274 vasodilator-stimulated phosphoprotein (A)	Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670)	[T]	Signal transduction mechanisms	WH1 domain;; VASP tetramerisation domain	Vasodilator-stimulated phosphoprotein GN=VASP OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: vasodilator-stimulated phosphoprotein isoform X1 [Loxodonta africana]
ENSG00000125755(SYMPK)	--	36.06872786	3501	33.96062511	3405	38.688866	3738	32.463719	2996	37.01326094	3506	34.64255765	3283	0.965839688	-0.255440365	normal	0.990878554	0.020735564	normal	0.9811405	-0.195458818	normal	0.486792329	-0.142107038	normal	--	--	--	"K06100|0|hsa:8189|SYMPK, SPK, SYM; symplekin; K06100 symplekin (A)"	mRNA surveillance pathway (ko03015);; Tight junction (ko04530)	[A]	RNA processing and modification	Domain of unknown function (DUF3453);; Symplekin tight junction protein C terminal	Symplekin GN=SYMPK OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: symplekin isoform X3 [Canis lupus familiaris] 
ENSG00000125772(GPCPD1)	--	14.34322668	1245	10.12666977	876	8.161463	688	9.661839912	843	10.12379495	872	18.41843985	1607	0.072629943	-0.592478674	normal	0.977182049	-0.027980878	normal	1.62E-10	1.213800337	up	0.797384309	0.222129947	normal	[C]	Energy production and conversion	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; Molecular Function: starch binding (GO:2001070);; 	"K18695|0|hsa:56261|GPCPD1, GDE5, GDPD6, PREI4; glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) (EC:3.1.4.2); K18695 glycerophosphocholine phosphodiesterase GPCPD1 [EC:3.1.4.2] (A)"	Glycerophospholipid metabolism (ko00564);; Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Glycerophosphoryl diester phosphodiesterase family;; Starch binding domain	Glycerophosphocholine phosphodiesterase GPCPD1 GN=GPCPD1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: glycerophosphocholine phosphodiesterase GPCPD1 isoform X1 [Mustela putorius furo] 
ENSG00000125775(SDCBP2)	--	0.138939	3	0.078263778	2	0.192741	4	0.080003536	2	0.237119	5	0.1200059	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PDZ domain (Also known as DHR or GLGF);; PDZ domain	Syntenin-2 GN=SDCBP2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: syntenin-2 [Galeopterus variegatus]
ENSG00000125779(PANK2)	--	26.64836039	1185	28.5753236	1355	30.35692281	1210	25.84963485	1201	27.22665683	1290	23.85018382	1218	0.981518104	-0.011468402	normal	0.979336446	-0.092242816	normal	0.981808857	0.001214131	normal	0.895946735	-0.037084919	normal	[H]	Coenzyme transport and metabolism	Molecular Function: pantothenate kinase activity (GO:0004594);; Molecular Function: ATP binding (GO:0005524);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; 	K09680|0|pps:100981323|PANK2; pantothenate kinase 2; K09680 type II pantothenate kinase [EC:2.7.1.33] (A)	Pantothenate and CoA biosynthesis (ko00770)	[H]	Coenzyme transport and metabolism	Fumble	"Pantothenate kinase 2, mitochondrial (Precursor) GN=PANK2 OS=Homo sapiens (Human) PE=1 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: pantothenate kinase 2, mitochondrial [Equus caballus]"
ENSG00000125780(TGM3)	--	0	0	0	0	0	0	0	0	0.0171141	0	0.069859	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein-glutamine gamma-glutamyltransferase activity (GO:0003810);; Biological Process: peptide cross-linking (GO:0018149);; 	"K05620|0|hsa:7053|TGM3, TGE; transglutaminase 3 (EC:2.3.2.13); K05620 transglutaminase 3 [EC:2.3.2.13] (A)"	--	--	--	"Transglutaminase family, C-terminal ig like domain;; Transglutaminase family;; Transglutaminase-like superfamily"	Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain (Precursor) GN=TGM3 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-glutamine gamma-glutamyltransferase E [Galeopterus variegatus]
ENSG00000125787(GNRH2)	--	0	0	0	0	0	0	0.185875882	2	0.09608323	0	0.51570397	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; 	"K05252|9.57045e-64|hsa:2797|GNRH2, GnRH-II, LH-RHII; gonadotropin-releasing hormone 2; K05252 gonadotropin-releasing hormone (A)"	GnRH signaling pathway (ko04912)	--	--	Gonadotropin-releasing hormone	GnRH-associated peptide 2 (Precursor) GN=GNRH2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: progonadoliberin-2 [Ursus maritimus]
ENSG00000125798(FOXA2)	--	16.91087983	740	13.50573988	594	14.59945012	658	14.43141113	633	15.66239888	688	15.410311	681	0.927533488	-0.255577555	normal	0.953446569	0.190069129	normal	0.97426514	0.041182731	normal	0.972572149	-0.013695471	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transcription factor binding (GO:0008134);; Molecular Function: protein domain specific binding (GO:0019904);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08035|0|ssc:100513828|FOXA2; forkhead box A2; K08035 forkhead box protein A2, hepatocyte nuclear factor 3-beta (A)"	Maturity onset diabetes of the young (ko04950)	[K]	Transcription	Fork head domain;; Forkhead N-terminal region;; HNF3 C-terminal domain	Hepatocyte nuclear factor 3-beta GN=FOXA2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hepatocyte nuclear factor 3-beta [Condylura cristata]
ENSG00000125812(GZF1)	--	7.789243148	709	9.316481398	807	6.617901791	607	7.44338339	684	6.018885917	548	8.484959252	773	0.97236042	-0.08243966	normal	0.130526175	-0.578494993	normal	0.845394969	0.339728687	normal	0.77952704	-0.103825119	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; BTB/POZ domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	GDNF-inducible zinc finger protein 1 GN=GZF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: GDNF-inducible zinc finger protein 1 [Galeopterus variegatus]
ENSG00000125814(NAPB)	--	4.001982	246	3.108127722	203	4.494958935	277	4.524089982	292	3.725050716	238	3.783718888	243	0.941917199	0.215242769	normal	0.944824411	0.206632448	normal	0.947536099	-0.196077301	normal	0.873172277	0.06910171	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Soluble NSF attachment protein, SNAP;; Tetratricopeptide repeat"	Beta-soluble NSF attachment protein GN=NAPB OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: beta-soluble NSF attachment protein isoform X2 [Pantholops hodgsonii] 
ENSG00000125816(NKX2-4)	--	0	0	0	0	0	0	0	0	0.0272694	0	0.0277821	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09344|2.75574e-140|hsa:644524|NKX2-4, NKX2.4, NKX2D; NK2 homeobox 4; K09344 homeobox protein Nkx-2.4 (A)"	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-2.4 GN=NKX2-4 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: homeobox protein Nkx-2.4 [Chrysochloris asiatica]
ENSG00000125817(CENPB)	--	88.7686	5148	75.347	4605	78.8124	4818	83.7012	4915	88.7856	5103	74.8205	4352	0.992043933	-0.097623077	normal	0.99039172	0.126678397	normal	0.98841563	-0.154996066	normal	0.883493494	-0.041532876	normal	--	--	"Cellular Component: chromosome, centromeric region (GO:0000775);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: chromatin binding (GO:0003682);; Cellular Component: nucleus (GO:0005634);; "	K11496|0|ggo:101128840|CENPB; LOW QUALITY PROTEIN: major centromere autoantigen B; K11496 centromere protein B (A)	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Centromere protein B dimerisation domain;; DDE superfamily endonuclease;; CENP-B N-terminal DNA-binding domain;; Tc5 transposase DNA-binding domain;; Winged helix-turn-helix DNA-binding	Major centromere autoantigen B GN=CENPB OS=Homo sapiens (Human) PE=1 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: major centromere autoantigen B [Pteropus alecto]
ENSG00000125818(PSMF1)	--	50.01932873	2556	51.40405148	2643	50.73179022	2464	56.639898	2874	58.59919929	2854	51.28572809	2569	0.984550161	0.138261557	normal	0.98746221	0.089333156	normal	0.98825513	0.051882005	normal	0.679563542	0.093080677	normal	--	--	--	"K06700|0|hsa:9491|PSMF1, PI31; proteasome (prosome, macropain) inhibitor subunit 1 (PI31); K06700 proteasome inhibitor subunit 1 (PI31) (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	PI31 proteasome regulator N-terminal;; PI31 proteasome regulator	Proteasome inhibitor PI31 subunit GN=PSMF1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome inhibitor PI31 subunit isoform X1 [Felis catus]
ENSG00000125820(NKX2-2)	--	0	0	0	0	0	0	0.0300269	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K08029|2.15251e-173|ptr:469894|NKX2-2; NK2 homeobox 2; K08029 homeobox protein Nkx-2.2 (A)	Maturity onset diabetes of the young (ko04950)	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-2.2 GN=NKX2-2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox protein Nkx-2.2 [Galeopterus variegatus]
ENSG00000125821(DTD1)	--	146.7311797	1727	117.3774845	1432	122.3012085	1564	132.1554957	1984	132.9830037	1842	122.7517684	1679	0.975897777	0.169171185	normal	0.875550931	0.341496293	normal	0.982078912	0.093982553	normal	0.274519506	0.199371061	normal	--	--	Molecular Function: aminoacyl-tRNA editing activity (GO:0002161);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: D-aminoacyl-tRNA deacylase activity (GO:0051499);; 	K07560|6.15516e-144|cfr:102521157|DTD1; D-tyrosyl-tRNA deacylase 1; K07560 D-tyrosyl-tRNA(Tyr) deacylase [EC:3.1.-.-] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	D-Tyr-tRNA(Tyr) deacylase	D-tyrosyl-tRNA(Tyr) deacylase 1 GN=DTD1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: D-tyrosyl-tRNA(Tyr) deacylase 1 [Sorex araneus]
ENSG00000125826(RBCK1)	--	95.87059462	3101	83.83164407	3103	88.25614107	3176	90.940833	2864	82.54556043	2546	188.7764158	6026	0.984976224	-0.145459275	normal	0.936432809	-0.306692516	normal	5.06E-06	0.915376554	normal	0.773660129	0.26706512	normal	--	--	--	K10630|0|pps:100981890|RBCK1; RanBP-type and C3HC4-type zinc finger containing 1; K10630 RanBP-type and C3HC4-type zinc finger-containing protein 1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain;; Ring finger domain;; zinc-RING finger domain	RanBP-type and C3HC4-type zinc finger-containing protein 1 GN=RBCK1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ranBP-type and C3HC4-type zinc finger-containing protein 1 isoform 2 [Canis lupus familiaris]
ENSG00000125827(TMX4)	--	11.1544061	1113	11.331572	1133	10.655186	1047	9.503173	951	11.00916659	1013	9.740732005	971	0.934980648	-0.257383734	normal	0.963933546	-0.182682203	normal	0.974086353	-0.116834401	normal	0.345144437	-0.18726539	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Thioredoxin	Thioredoxin-related transmembrane protein 4 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	CO	"Energy production and conversion;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin-related transmembrane protein 4 [Ceratotherium simum simum]
ENSG00000125834(STK35)	--	8.8528	1043	9.23582	1097	8.70281	1033	9.15425	1076	9.67064	1135	9.32913	1104	0.980142275	0.014086227	normal	0.98009873	0.027664721	normal	0.977447443	0.087484569	normal	0.883616512	0.042001151	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08859|0|pon:100454523|STK35; serine/threonine kinase 35; K08859 serine/threonine kinase 35 [EC:2.7.11.1] (A)	--	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 35 GN=STK35 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 35 [Galeopterus variegatus]
ENSG00000125835(SNRPB)	--	384.277	7399	405.293	7893	392.587	7706	435.513	8331	413.72	7776	363.2447	6985	0.993114515	0.14029965	normal	0.995067808	-0.042963795	normal	0.992240365	-0.149982583	normal	0.965475915	-0.015826134	normal	[K]	Transcription	--	--	--	[K]	Transcription	LSM domain	Small nuclear ribonucleoprotein-associated proteins B and B' GN=SNRPB OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	SNRPB protein [Bos taurus]
ENSG00000125841(NRSN2)	--	44.68621177	1660	44.83234327	1512	47.00779683	1784	47.65348853	1731	47.72027941	1765	53.97058848	1939	0.985040956	0.029563424	normal	0.967265068	0.201596714	normal	0.982426064	0.111814806	normal	0.605720556	0.112484135	normal	--	--	--	--	--	--	--	Neurensin	Neurensin-2 GN=NRSN2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: neurensin-2 [Ceratotherium simum simum]
ENSG00000125843(AP5S1)	--	11.11763302	480	10.77481553	502	10.19451256	443	8.769533803	421	9.518043601	441	11.2472474	508	0.940256209	-0.219296214	normal	0.944321103	-0.207667238	normal	0.950911993	0.188628606	normal	0.807636512	-0.077604756	normal	--	--	Biological Process: double-strand break repair via homologous recombination (GO:0000724);; Biological Process: endosomal transport (GO:0016197);; Cellular Component: AP-type membrane coat adaptor complex (GO:0030119);; 	--	--	--	--	AP-5 complex subunit sigma-1	AP-5 complex subunit sigma-1 GN=AP5S1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-5 complex subunit sigma-1 isoform X2 [Ursus maritimus] 
ENSG00000125844(RRBP1)	--	44.70376655	4956	45.654809	4678	49.75851346	4845	53.345685	5891	61.124987	6537	50.38735394	5347	0.98343787	0.21844193	normal	0.683461796	0.461183622	normal	0.990580907	0.13390177	normal	0.116456344	0.274522054	normal	[N]	Cell motility	Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of endoplasmic reticulum membrane (GO:0030176);; 	K14000|0|mcf:102134673|RRBP1; ribosome binding protein 1; K14000 ribosome-binding protein 1 (A)	Protein processing in endoplasmic reticulum (ko04141)	--	--	Ribosome receptor lysine/proline rich region;; Pentapeptide repeats (8 copies)	Ribosome-binding protein 1 GN=RRBP1 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ribosome-binding protein 1 [Galeopterus variegatus]
ENSG00000125845(BMP2)	--	0.870653493	56	1.149687	60	0.684428502	44	2.816096	172	6.416111	389	6.583483	419	3.22E-07	1.562406047	up	0	2.645299694	up	0	3.199681149	up	0.000611913	2.595490566	up	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04662|0|hsa:650|BMP2, BDA2, BMP2A; bone morphogenetic protein 2; K04662 bone morphogenetic protein 2/4 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Hedgehog signaling pathway (ko04340);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Bone morphogenetic protein 2 (Precursor) GN=BMP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein 2 [Galeopterus variegatus]
ENSG00000125846(ZNF133)	--	5.73231936	294	6.310981057	264	5.560206017	300	5.788568595	259	7.933932729	296	8.051560498	329	0.942534548	-0.21251204	normal	0.956809031	0.142859542	normal	0.960848857	0.124235431	normal	0.967377887	0.022766636	normal	[R]	General function prediction only	--	"K09228|0|hsa:7692|ZNF133, ZNF150, pHZ-13, pHZ-66; zinc finger protein 133; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; CHY zinc finger"	Zinc finger protein 133 GN=ZNF133 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 133 isoform X3 [Panthera tigris altaica]
ENSG00000125848(FLRT3)	--	5.513482	409	8.6864458	617	3.8917631	258	2.768156954	203	5.590189	401	5.673810001	407	2.17E-05	-1.035811019	down	0.055504935	-0.641129542	normal	0.085515434	0.646324686	normal	0.674825578	-0.365224501	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K16362|0|ptr:469886|FLRT3; fibronectin leucine rich transmembrane protein 3; K16362 leucine-rich repeat transmembrane protein FLRT (A)	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies)	Leucine-rich repeat transmembrane protein FLRT3 (Precursor) GN=FLRT3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat transmembrane protein FLRT3 [Oryctolagus cuniculus] 
ENSG00000125850(OVOL2)	--	0	0	0	0	0	0	0.0311428	1	0.0304164	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09216|8.45681e-160|hsa:58495|OVOL2, EUROIMAGE566589, ZNF339; ovo-like zinc finger 2; K09216 ovo (A)"	--	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Transcription factor Ovo-like 2 GN=OVOL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor Ovo-like 2 [Pteropus alecto]
ENSG00000125851(PCSK2)	--	0	0	0	0	0	0	0	0	0	0	0.022468419	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01360|0|pon:100171744|PCSK2, NEC2; proprotein convertase subtilisin/kexin type 2 (EC:3.4.21.94); K01360 proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family;; Proprotein convertase P-domain	Neuroendocrine convertase 2 (Precursor) GN=PCSK2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: neuroendocrine convertase 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000125863(MKKS)	--	23.6615026	1356	72.15826567	1199	77.75752204	1287	26.7274104	1641	110.151312	1801	27.441878	1618	0.951117561	0.24413405	normal	0.135951977	0.564954849	normal	0.892282217	0.321570414	normal	0.016046031	0.376143243	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09492|0|hsa:8195|MKKS, BBS6, HMCS, KMS, MKS; McKusick-Kaufman syndrome; K09492 McKusick-Kaufman syndrome protein (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin GN=MKKS OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mcKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin [Galeopterus variegatus]
ENSG00000125864(BFSP1)	--	3.76745242	175	2.729925897	133	2.933577962	139	3.379952822	160	2.875689949	141	3.92819028	192	0.957953046	-0.158657798	normal	0.965899675	0.062155917	normal	0.779108708	0.453514452	normal	0.802393844	0.120496159	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K10378|0|pps:100967505|BFSP1; beaded filament structural protein 1, filensin; K10378 filensin (A)"	--	--	--	Intermediate filament protein	Filensin GN=BFSP1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: filensin [Tupaia chinensis] 
ENSG00000125868(DSTN)	--	273.260387	8758	358.5290941	11644	308.0930431	9842	377.0249598	12225	355.013498	11339	369.315405	11854	0.790336451	0.450261719	normal	0.996261819	-0.05971203	normal	0.985355706	0.260022644	normal	0.313585257	0.206399856	normal	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	K10363|9.94472e-117|ssc:445516|DSTN; destrin (actin depolymerizing factor); K10363 destrin (actin-depolymerizing factor) (A)	--	[Z]	Cytoskeleton	Cofilin/tropomyosin-type actin-binding protein	Destrin GN=DSTN OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	Destrin [Myotis brandtii]
ENSG00000125869(LAMP5)	--	0	0	0.03074745	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Lysosome-associated membrane glycoprotein (Lamp)	Lysosome-associated membrane glycoprotein 5 (Precursor) GN=LAMP5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lysosome-associated membrane glycoprotein 5 isoform X1 [Leptonychotes weddellii]
ENSG00000125870(SNRPB2)	--	50.06745703	1315	55.1409027	1438	50.42550278	1289	55.928319	1505	55.84017923	1442	50.34668245	1288	0.972492671	0.163689559	normal	0.983129946	-0.017400795	normal	0.982434495	-0.00940008	normal	0.865964641	0.045518979	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K11094|1.94978e-141|pon:100445291|SNRPB2; small nuclear ribonucleoprotein polypeptide B; K11094 U2 small nuclear ribonucleoprotein B'' (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	U2 small nuclear ribonucleoprotein B'' GN=SNRPB2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U2 small nuclear ribonucleoprotein B'' isoform X1 [Tupaia chinensis] 
ENSG00000125871(MGME1)	--	20.998301	974	23.68618	1104	23.869711	1105	20.97978	959	19.691656	904	23.231815	1073	0.978076612	-0.053138742	normal	0.894899509	-0.309302947	normal	0.979664376	-0.050617433	normal	0.528035297	-0.137335213	normal	--	--	--	--	--	--	--	PD-(D/E)XK nuclease superfamily	Mitochondrial genome maintenance exonuclease 1 {ECO:0000255|HAMAP-Rule:MF_03030} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitochondrial genome maintenance exonuclease 1 [Galeopterus variegatus]
ENSG00000125872(LRRN4)	--	0.0844428	4	0	0	0	0	0.0211073	1	0.0408045	1	0.0414002	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Fibronectin type III domain;; Leucine Rich Repeat	Leucine-rich repeat neuronal protein 4 (Precursor) GN=LRRN4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: leucine-rich repeat neuronal protein 4 [Ceratotherium simum simum]
ENSG00000125875(TBC1D20)	--	20.23395	1542	21.95625	1677	20.02784	1520	18.345224	1430	20.02120718	1565	25.071805	1955	0.976796017	-0.139475518	normal	0.979610587	-0.121033575	normal	0.853632869	0.354494069	normal	0.902702768	0.042475421	normal	[R]	General function prediction only	--	--	--	[T]	Signal transduction mechanisms	Rab-GTPase-TBC domain	TBC1 domain family member 20 GN=TBC1D20 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	TBC1 domain family member 20 [Bos taurus] 
ENSG00000125877(ITPA)	--	36.87364	660	43.45076	786	37.35378	679	55.34643	1011	58.04667	1002	51.27912	950	0.096443986	0.5833082	normal	0.869412484	0.328294101	normal	0.44403261	0.475325435	normal	0.00492586	0.458084831	normal	[F]	Nucleotide transport and metabolism	Biological Process: nucleoside triphosphate catabolic process (GO:0009143);; Molecular Function: nucleoside-triphosphate diphosphatase activity (GO:0047429);; 	K01519|1.35815e-140|ggo:101149278|ITPA; inosine triphosphate pyrophosphatase; K01519 inosine triphosphate pyrophosphatase [EC:3.6.1.19] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Ham1 family	Inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148} OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: inosine triphosphate pyrophosphatase [Vicugna pacos]
ENSG00000125878(TCF15)	--	0	0	0.0348268	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09070|8.77483e-90|hsa:6939|TCF15, EC2, PARAXIS, bHLHa40; transcription factor 15 (basic helix-loop-helix); K09070 transcription factor 15 (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Transcription factor 15 GN=TCF15 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: transcription factor 15 [Ochotona princeps]
ENSG00000125885(MCM8)	--	18.07149	1635	18.9075966	1707	20.593608	1813	15.9404107	1462	13.7218526	1295	15.51827335	1363	0.968569025	-0.191988662	normal	0.690608322	-0.419509323	normal	0.679569851	-0.419479832	normal	0.030359715	-0.344636428	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; Molecular Function: ATPase activity (GO:0016887);; 	"K10737|0|hsa:84515|MCM8, C20orf154, dJ967N21.5; minichromosome maintenance complex component 8 (EC:3.6.4.12); K10737 DNA helicase MCM8 [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; Magnesium chelatase, subunit ChlI;; AAA domain (dynein-related subfamily);; MCM N-terminal domain;; Putative binding domain"	DNA helicase MCM8 GN=MCM8 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA helicase MCM8 [Galeopterus variegatus]
ENSG00000125895(TMEM74B)	--	5.925650565	209	3.193669	119	4.501740007	158	4.336311715	150	3.393635042	118	2.849347711	103	0.652553357	-0.504968555	normal	0.967773373	-0.033177856	normal	0.49351675	-0.618187137	normal	0.380800599	-0.411867342	normal	--	--	--	--	--	--	--	Neurensin	Transmembrane protein 74B GN=TMEM74B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 74B [Vicugna pacos]
ENSG00000125898(FAM110A)	--	6.32102443	156	5.314403582	140	5.389562474	141	6.303494662	168	4.984388833	126	5.811269493	151	0.965661218	0.075367589	normal	0.957538343	-0.171476063	normal	0.965448223	0.089632825	normal	1	0.004461883	normal	--	--	--	--	--	--	--	Centrosome-associated C terminus;; Centrosome-associated N terminus	Protein FAM110A GN=FAM110A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM110A isoform X1 [Equus caballus] 
ENSG00000125901(MRPS26)	--	63.7512	1244	63.6907	1303	69.2863	1429	73.5405	1464	74.3618	1458	67.5137	1329	0.963004457	0.203864518	normal	0.975278817	0.140572785	normal	0.978652617	-0.112832403	normal	0.756655396	0.075231047	normal	--	--	Cellular Component: mitochondrial small ribosomal subunit (GO:0005763);; 	K17405|6.59608e-120|ptr:458055|MRPS26; mitochondrial ribosomal protein S26; K17405 small subunit ribosomal protein S26 (A)	--	[S]	Function unknown	Mitochondrial ribosome subunit S26	"28S ribosomal protein S26, mitochondrial (Precursor) GN=MRPS26 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S26, mitochondrial [Ceratotherium simum simum]"
ENSG00000125910(S1PR4)	--	0.149419	3	0.189334	4	0.36886	7	0.342312	7	0.241013	4	0.389999	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04293|0|ptr:455581|S1PR4, EDG6; sphingosine-1-phosphate receptor 4; K04293 sphingosine 1-phosphate receptor 4 (A)"	FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family)	Sphingosine 1-phosphate receptor 4 GN=S1PR4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: sphingosine 1-phosphate receptor 4 [Equus caballus]
ENSG00000125912(NCLN)	--	33.75742588	2406	33.69159441	2437	36.86673538	2716	39.98657286	2784	38.81005411	2717	37.77611294	2670	0.979280561	0.179583629	normal	0.983951556	0.135402153	normal	0.989177794	-0.032916694	normal	0.688938656	0.091209574	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein processing (GO:0016485);; 	--	--	[E]	Amino acid transport and metabolism	Peptidase family M28;; Nicastrin	Nicalin (Precursor) GN=NCLN OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: nicalin [Odobenus rosmarus divergens]
ENSG00000125931(CITED1)	--	0.088460732	1	0.373027657	2	0	0	0.171982651	2	0.0545304	0	0.684643883	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	CITED	Cbp/p300-interacting transactivator 1 GN=CITED1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cbp/p300-interacting transactivator 1 isoformX2 [Equus caballus]
ENSG00000125944(HNRNPR)	--	84.28615337	4359	87.10233078	4721	83.7264005	4478	90.7732297	4815	83.59434395	4314	75.0919889	3925	0.990854829	0.112668537	normal	0.988361405	-0.151442094	normal	0.983064559	-0.1983817	normal	0.755536218	-0.076509869	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13161|0|mcf:101866820|uncharacterized LOC101866820; K13161 heterogeneous nuclear ribonucleoprotein R (A)	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoprotein R GN=HNRNPR OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein R isoform X2 [Chrysochloris asiatica]
ENSG00000125945(ZNF436)	--	3.047966	231	3.41429803	259	2.88544767	212	2.753165129	206	2.377263	177	3.664684	273	0.949030715	-0.19470839	normal	0.407163048	-0.566601644	normal	0.860781907	0.354312388	normal	0.771144784	-0.118443505	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:80818|ZNF436, ZNF, Zfp46; zinc finger protein 436; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal"	Zinc finger protein 436 GN=ZNF436 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	Zinc finger protein 436 [Tupaia chinensis]
ENSG00000125952(MAX)	--	24.3082128	652	25.2650493	690	24.41709698	653	34.2233992	923	28.29614975	763	30.336702	845	0.46759974	0.469692076	normal	0.968228159	0.123402865	normal	0.806044645	0.362836275	normal	0.078896627	0.321719841	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K04453|3.42429e-98|tup:102480187|MAX; MYC associated factor X; K04453 Max protein (A)	MAPK signaling pathway (ko04010);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Small cell lung cancer (ko05222)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Protein max GN=MAX OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein max isoform X1 [Lipotes vexillifer]
ENSG00000125954(CHURC1-FNTB)	--	46.31978704	1553	47.90674227	1626	45.94457807	1656	55.64443849	1952	57.80043064	1922	52.83062391	1890	0.922364597	0.298798821	normal	0.964060486	0.219666429	normal	0.972985336	0.182236238	normal	0.183951724	0.23233587	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: catalytic activity (GO:0003824);; Biological Process: multicellular organismal development (GO:0007275);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	"K05954|0|oas:101110335|FNTB; farnesyltransferase, CAAX box, beta; K05954 protein farnesyltransferase subunit beta [EC:2.5.1.58] (A)"	Terpenoid backbone biosynthesis (ko00900)	[O]	"Posttranslational modification, protein turnover, chaperones"	Prenyltransferase and squalene oxidase repeat;; Churchill protein;; Prenyltransferase-like;; Prenyltransferase-like	Protein farnesyltransferase subunit beta GN=FNTB OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: LOW QUALITY PROTEIN: farnesyltransferase, CAAX box, beta [Ceratotherium simum simum]"
ENSG00000125962(ARMCX5)	--	7.417431258	274	7.35253535	275	7.935296977	306	6.99310625	268	7.4717684	308	7.161936134	278	0.965736824	-0.062421219	normal	0.957121614	0.14133747	normal	0.957509839	-0.145980976	normal	0.965475915	-0.022507323	normal	--	--	--	--	--	--	--	Armadillo-like	Armadillo repeat-containing X-linked protein 5 GN=ARMCX5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing X-linked protein 5 [Galeopterus variegatus]
ENSG00000125966(MMP24)	--	29.6237	2551	30.8366	2701	31.7569	2789	32.0866	2758	31.8383	2727	35.168	3042	0.987764239	0.081679977	normal	0.989160303	-0.007601262	normal	0.986844014	0.116920056	normal	0.797742141	0.06385083	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	K08002|0|ptr:469925|MMP24; matrix metallopeptidase 24 (membrane-inserted); K08002 matrix metalloproteinase-24 (membrane-inserted) [EC:3.4.24.-] (A)	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Domain of unknown function (DUF3377);; Putative peptidoglycan binding domain;; Astacin (Peptidase family M12A)	Processed matrix metalloproteinase-24 (Precursor) GN=MMP24 OS=Homo sapiens (Human) PE=2 SV=1	OW	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	PREDICTED: matrix metalloproteinase-24 [Equus caballus] 
ENSG00000125967(NECAB3)	--	8.535830319	387	8.636514252	421	8.917618632	437	6.220306217	285	7.777155202	360	6.091080487	307	0.578582798	-0.470019877	normal	0.927713553	-0.24629201	normal	0.40019194	-0.51554614	normal	0.068646026	-0.407859541	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	Antibiotic biosynthesis monooxygenase;; EF hand;; EF hand	N-terminal EF-hand calcium-binding protein 3 GN=NECAB3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: N-terminal EF-hand calcium-binding protein 3 [Ceratotherium simum simum]
ENSG00000125968(ID1)	--	192.4677	2784	126.8951	1881	142.99814	2134	114.99198	1699	120.33972	1734	99.66657	1464	0.001433446	-0.742775087	normal	0.979281298	-0.138706318	normal	0.154493025	-0.551461363	normal	0.077633318	-0.495075506	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K04680|1.77557e-91|ptr:469912|ID1; inhibitor of DNA binding 1, dominant negative helix-loop-helix protein; K04680 DNA-binding protein inhibitor ID1 (A)"	Rap1 signaling pathway (ko04015);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550)	--	--	Helix-loop-helix DNA-binding domain	DNA-binding protein inhibitor ID-1 GN=ID1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA-binding protein inhibitor ID-1 [Ochotona princeps]
ENSG00000125970(RALY)	--	92.1448102	2773	87.09980114	2694	88.79365203	2664	88.03154125	2554	81.75451445	2406	93.32002186	2659	0.983320061	-0.149435044	normal	0.978157331	-0.184430142	normal	0.989292465	-0.0109955	normal	0.590187453	-0.114968447	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K12895|1.92694e-131|pps:100973054|RALY; RALY heterogeneous nuclear ribonucleoprotein; K12895 heterogeneous nuclear ribonucleoprotein C-like 2 (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein Raly GN=RALY OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein Raly isoform X3 [Panthera tigris altaica]
ENSG00000125971(DYNLRB1)	--	127.872176	1108	122.591847	1075	126.803015	1108	120.3556656	1111	123.79346	1067	150.4954969	1307	0.980487887	-0.026894086	normal	0.979521929	-0.032157634	normal	0.952165543	0.229720827	normal	0.814973942	0.061935921	normal	--	--	--	"K10419|9.34436e-64|pps:100976332|DYNLRB1; dynein, light chain, roadblock-type 1; K10419 dynein light chain roadblock-type (A)"	--	[DN]	"Cell cycle control, cell division, chromosome partitioning;; Cell motility"	Roadblock/LC7 domain	Dynein light chain roadblock-type 1 GN=DYNLRB1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: dynein light chain roadblock-type 1-like [Bubalus bubalis]
ENSG00000125977(EIF2S2)	--	81.85501099	3243	84.2590564	3270	81.608123	3212	78.33549877	3086	79.1651996	3062	76.50316012	3116	0.988406482	-0.102373496	normal	0.987409735	-0.116187369	normal	0.990079133	-0.052043222	normal	0.689714633	-0.091250482	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	"K03238|0|pps:100973634|EIF2S2; eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa; K03238 translation initiation factor 2 subunit 2 (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Domain found in IF2B/IF5	Eukaryotic translation initiation factor 2 subunit 2 GN=EIF2S2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 2 subunit 2 [Sus scrofa] 
ENSG00000125991(ERGIC3)	--	124.0777908	2964	128.237495	3234	110.6106736	2753	112.5002014	2762	120.9107188	2898	132.5411868	3213	0.985598068	-0.132593168	normal	0.98141324	-0.179599867	normal	0.97526411	0.214515751	normal	0.902537736	-0.033587185	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endoplasmic reticulum vesicle transporter;; Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC)	Endoplasmic reticulum-Golgi intermediate compartment protein 3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	endoplasmic reticulum-Golgi intermediate compartment protein 3 [Oryctolagus cuniculus] 
ENSG00000125995(ROMO1)	--	172.52069	533	167.977635	564	164.55092	557	198.79635	669	155.7188	487	183.90216	601	0.895509228	0.296274784	normal	0.935841268	-0.232528264	normal	0.968613915	0.101131831	normal	0.830751125	0.065505559	normal	--	--	--	--	--	[S]	Function unknown	Reactive mitochondrial oxygen species modulator 1	Reactive oxygen species modulator 1 GN=ROMO1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	hypothetical protein CB1_001108037 [Camelus ferus]
ENSG00000125999(BPIFB1)	--	0	0	0	0	0	0	0.031937125	1	0.031087969	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[V]	Defense mechanisms	"LBP / BPI / CETP family, N-terminal domain;; LBP / BPI / CETP family, C-terminal domain"	BPI fold-containing family B member 1 (Precursor) GN=BPIFB1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: BPI fold-containing family B member 1 [Galeopterus variegatus]
ENSG00000126001(CEP250)	--	14.79999747	2664	15.03132516	2464	16.77308196	2841	12.36208974	2078	11.4712384	1719	13.68063084	2066	0.802666953	-0.388975921	normal	0.21497983	-0.540459817	normal	0.519378995	-0.467556886	normal	0.001605994	-0.463850436	normal	--	--	--	"K16464|0|hsa:11190|CEP250, C-NAP1, CEP2, CNAP1; centrosomal protein 250kDa; K16464 centrosomal protein CEP250 (A)"	--	--	--	"Ciliary rootlet component, centrosome cohesion"	Centrosome-associated protein CEP250 GN=CEP250 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosome-associated protein CEP250 [Ceratotherium simum simum]
ENSG00000126003(PLAGL2)	--	7.32475	717	7.53422	732	7.17404	696	6.94849	674	8.00511	778	6.84449	671	0.968620283	-0.119791962	normal	0.97388557	0.066366944	normal	0.973631531	-0.060931136	normal	0.908816099	-0.036072338	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein PLAGL2 GN=PLAGL2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein PLAGL2 isoformX1 [Canis lupus familiaris] 
ENSG00000126005(MMP24-AS1)	--	77.9946	910	64.0698	777	64.2101	805	63.4667	764	69.8697	842	69.2696	836	0.912691352	-0.282604606	normal	0.972775775	0.094302734	normal	0.976469614	0.046137661	normal	0.863451396	-0.050178859	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000126010(GRPR)	--	0	0	0	0	0.276924	7	0.138692	4	0.235924	6	0.0688977	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04169|0|hsa:2925|GRPR, BB2; gastrin-releasing peptide receptor; K04169 gastrin-releasing peptide receptor (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srsx	Gastrin-releasing peptide receptor GN=GRPR OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: gastrin-releasing peptide receptor [Felis catus] 
ENSG00000126012(KDM5C)	--	24.94072141	3109	27.08761265	3518	24.02351691	3117	22.7002372	2887	24.70311471	3066	27.8800096	3552	0.985684975	-0.13764116	normal	0.975857637	-0.219723073	normal	0.9825737	0.180100077	normal	0.823286826	-0.056529689	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706);; Biological Process: oxidation-reduction process (GO:0055114);; "	K11446|0|pps:100970129|KDM5C; lysine (K)-specific demethylase 5C; K11446 histone demethylase JARID1 [EC:1.14.11.-] (A)	--	[R]	General function prediction only	"PLU-1-like protein;; JmjC domain, hydroxylase;; ARID/BRIGHT DNA binding domain;; C5HC2 zinc finger;; PHD-finger;; jmjN domain"	Lysine-specific demethylase 5C GN=KDM5C OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lysine-specific demethylase 5C isoform X1 [Vicugna pacos]
ENSG00000126016(AMOT)	--	0.637447283	85	0.2995063	40	0.554652539	64	0.057123241	7	0.134902884	17	0.072944823	10	8.44E-13	-3.369381805	down	0.51296494	-1.185216472	normal	8.30E-07	-2.516242133	down	0.000163298	-2.494590004	down	--	--	--	K16819|0|hsa:154796|AMOT; angiomotin; K16819 angiomotin (A)	Hippo signaling pathway (ko04390)	--	--	Angiomotin C terminal	Angiomotin GN=AMOT OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: angiomotin [Lipotes vexillifer]
ENSG00000126062(TMEM115)	--	24.2594	943	23.4348	927	22.1491	884	23.7404	927	25.601	991	24.264	950	0.977578297	-0.055429605	normal	0.97640304	0.074771175	normal	0.974874291	0.095432188	normal	0.899750752	0.037336974	normal	--	--	"Biological Process: retrograde vesicle-mediated transport, Golgi to ER (GO:0006890);; Cellular Component: integral component of membrane (GO:0016021);; "	--	--	[S]	Function unknown	Eukaryotic integral membrane protein (DUF1751)	Transmembrane protein 115 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	transmembrane protein 115 [Bos taurus] 
ENSG00000126067(PSMB2)	--	40.52302063	1744	43.07402877	1835	41.74150817	1784	55.37641466	2379	54.21165134	2323	44.00692957	1891	0.709369524	0.416807485	normal	0.9138641	0.318548737	normal	0.984458255	0.075679987	normal	0.096701697	0.276058014	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02734|2.03692e-130|ptr:469277|PSMB2; proteasome (prosome, macropain) subunit, beta type, 2 (EC:3.4.25.1); K02734 20S proteasome subunit beta 4 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-2 GN=PSMB2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-2 isoform X2 [Camelus ferus] 
ENSG00000126070(AGO3)	--	2.888706	377	3.570251	431	4.27369858	383	3.181388005	415	3.1861052	392	4.090417134	424	0.96410843	0.107297682	normal	0.9560869	-0.157680362	normal	0.960308453	0.137910688	normal	0.951909417	0.026383234	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	"K11593|0|ptr:469279|AGO3, EIF2C3; argonaute RISC catalytic component 3; K11593 eukaryotic translation initiation factor 2C (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Piwi domain;; PAZ domain;; Domain of unknown function (DUF1785)	Protein argonaute-3 {ECO:0000255|HAMAP-Rule:MF_03032} GN=AGO3 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: protein argonaute-3 isoform X2 [Myotis brandtii] 
ENSG00000126088(UROD)	--	19.78649004	376	18.96382841	396	20.48985179	424	26.91479429	541	30.9753301	612	22.50032017	459	0.440619302	0.492378226	normal	0.107312439	0.604733386	normal	0.965316168	0.105775764	normal	0.043333463	0.40924725	normal	[H]	Coenzyme transport and metabolism	Molecular Function: uroporphyrinogen decarboxylase activity (GO:0004853);; Biological Process: porphyrin-containing compound biosynthetic process (GO:0006779);; 	"K01599|0|hsa:7389|UROD, PCT, UPD; uroporphyrinogen decarboxylase (EC:4.1.1.37); K01599 uroporphyrinogen decarboxylase [EC:4.1.1.37] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	Uroporphyrinogen decarboxylase (URO-D)	Uroporphyrinogen decarboxylase GN=UROD OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: uroporphyrinogen decarboxylase [Ceratotherium simum simum]
ENSG00000126091(ST3GAL3)	--	3.996220205	115	2.842255029	71	3.606475726	115	2.662013249	75	4.450674403	117	3.603646317	90	0.621861446	-0.63688175	normal	0.510057583	0.687672822	normal	0.923344618	-0.356613856	normal	0.855849551	-0.114098268	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K00781|0|cjc:100411797|ST3GAL3; ST3 beta-galactoside alpha-2,3-sialyltransferase 3; K00781 N-acetyllactosaminide alpha-2,3-sialyltransferase (sialyltransferase 6) [EC:2.4.99.6] (A)"	Other types of O-glycan biosynthesis (ko00514);; Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase GN=ST3GAL3 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase isoform X1 [Mustela putorius furo] "
ENSG00000126106(TMEM53)	--	8.660184	187	7.069654	165	7.626150577	190	4.955456	117	7.254364906	129	8.075834008	169	0.196843388	-0.700019402	normal	0.883850882	-0.372648122	normal	0.95465689	-0.175783188	normal	0.228466741	-0.405104042	normal	--	--	--	--	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF829)	Transmembrane protein 53 GN=TMEM53 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 53 isoform X1 [Ailuropoda melanoleuca]
ENSG00000126107(HECTD3)	--	8.68309315	636	6.810139	495	9.086962671	676	10.15326719	741	10.367459	746	10.097272	730	0.95505376	0.189190797	normal	0.161508054	0.568895616	normal	0.970828363	0.102361368	normal	0.168492753	0.274166776	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	K12233|0|hsa:79654|HECTD3; HECT domain containing E3 ubiquitin protein ligase 3; K12233 E3 ubiquitin-protein ligase HECTD3 [EC:6.3.2.19] (A)	--	[OK]	"Posttranslational modification, protein turnover, chaperones;; Transcription"	"HECT-domain (ubiquitin-transferase);; Anaphase-promoting complex, subunit 10 (APC10)"	E3 ubiquitin-protein ligase HECTD3 GN=HECTD3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase HECTD3 [Camelus dromedarius]
ENSG00000126214(KLC1)	--	68.43929851	3677	71.06215409	3806	69.58682965	3898	70.26251137	3937	71.84066762	3710	62.12886048	3376	0.991059043	0.067707929	normal	0.990926031	-0.058259485	normal	0.978266363	-0.215620657	normal	0.786760395	-0.067687632	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10407|0|mcf:101865498|uncharacterized LOC101865498; K10407 kinesin light chain (A)	Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Tetratricopeptide repeat;; Rabaptin-like protein;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Kinesin light chain 1 GN=KLC1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin light chain 1 isoform X4 [Monodelphis domestica]
ENSG00000126215(XRCC3)	--	23.015532	985	23.057423	1023	23.21674228	1104	20.53257	825	21.127434	882	20.251855	893	0.911705429	-0.286073502	normal	0.944805104	-0.235007589	normal	0.88771608	-0.313820617	normal	0.118234783	-0.280097237	normal	[L]	"Replication, recombination and repair"	--	"K10880|0|hsa:7517|XRCC3, CMM6; X-ray repair complementing defective repair in Chinese hamster cells 3; K10880 DNA-repair protein XRCC3 (A)"	Homologous recombination (ko03440)	[L]	"Replication, recombination and repair"	Rad51;; AAA domain;; recA bacterial DNA recombination protein	DNA repair protein XRCC3 GN=XRCC3 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein XRCC3 [Ceratotherium simum simum]
ENSG00000126216(TUBGCP3)	--	10.93782925	678	11.13853688	700	10.42685085	646	8.3850604	533	9.834155709	600	8.685572473	562	0.776258326	-0.37701569	normal	0.933630324	-0.243250693	normal	0.947329139	-0.208731135	normal	0.17234936	-0.277026421	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: spindle pole (GO:0000922);; Cellular Component: microtubule organizing center (GO:0005815);; Biological Process: microtubule nucleation (GO:0007020);; Molecular Function: gamma-tubulin binding (GO:0043015);; 	"K16570|0|ptr:452676|TUBGCP3; tubulin, gamma complex associated protein 3; K16570 gamma-tubulin complex component 3 (A)"	--	[Z]	Cytoskeleton	Spc97 / Spc98 family	Gamma-tubulin complex component 3 GN=TUBGCP3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: gamma-tubulin complex component 3 [Pteropus alecto]
ENSG00000126217(MCF2L)	--	1.1730308	76	0.760828889	41	0.805999205	46	0.898431575	29	1.762662629	77	1.607247558	54	0.007519965	-1.374092785	down	0.446283097	0.864199456	normal	0.973546056	0.216459925	normal	0.976887251	-0.046498637	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Divergent CRAL/TRIO domain;; Spectrin repeat;; PH domain;; Variant SH3 domain;; SH3 domain	Guanine nucleotide exchange factor DBS GN=MCF2L OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide exchange factor DBS isoform X3 [Galeopterus variegatus]
ENSG00000126218(F10)	--	0.063241115	2	0.062410967	2	0	0	0.032822248	1	0	0	0.032636733	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	K01314|0|ptr:452679|F10; coagulation factor X; K01314 coagulation factor X [EC:3.4.21.6] (A)	Complement and coagulation cascades (ko04610)	--	--	Trypsin;; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain;; Coagulation Factor Xa inhibitory site;; EGF-like domain;; Complement Clr-like EGF-like;; Human growth factor-like EGF	Activated factor Xa heavy chain (Precursor) GN=F10 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: coagulation factor X [Loxodonta africana]
ENSG00000126226(PCID2)	--	15.63894904	474	15.33677506	476	17.70200816	540	16.97169401	525	14.72916128	457	16.803867	521	0.96514613	0.116239998	normal	0.967399939	-0.079934755	normal	0.9708506	-0.059796976	normal	0.985893701	-0.008508469	normal	[L]	"Replication, recombination and repair"	Molecular Function: protein binding (GO:0005515);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	PCI domain	PCI domain-containing protein 2 GN=PCID2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PCI domain-containing protein 2 [Pteropus alecto]
ENSG00000126231(PROZ)	--	0.074650111	2	0.109843405	3	0.108435189	2	0	0	0.072855438	1	0.221622566	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin;; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain;; Coagulation Factor Xa inhibitory site;; EGF-like domain;; Complement Clr-like EGF-like;; Calcium-binding EGF domain	Vitamin K-dependent protein Z (Precursor) GN=PROZ OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: vitamin K-dependent protein Z isoform X1 [Equus caballus]
ENSG00000126243(LRFN3)	--	19.09721	915	18.82598	908	18.68212	917	17.83953	876	17.37937	806	19.62856	971	0.974645454	-0.093512633	normal	0.95735413	-0.192997597	normal	0.97678723	0.074139287	normal	0.800153572	-0.067461312	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16356|0|hsa:79414|LRFN3, FIGLER1, SALM4; leucine rich repeat and fibronectin type III domain containing 3; K16356 leucine-rich repeat and fibronectin type-III domain-containing protein 3 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Fibronectin type III domain;; Leucine rich repeat;; Leucine Rich repeat	Leucine-rich repeat and fibronectin type-III domain-containing protein 3 (Precursor) GN=LRFN3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and fibronectin type-III domain-containing protein 3 [Galeopterus variegatus]
ENSG00000126246(IGFLR1)	--	5.251357952	119	4.00063791	72	3.785610895	78	4.933184144	106	5.280037001	125	7.101778	133	0.959014288	-0.195059194	normal	0.296439796	0.762142075	normal	0.278053404	0.750322246	normal	0.320841618	0.415610798	normal	--	--	--	--	--	--	--	--	IGF-like family receptor 1 (Precursor) GN=IGFLR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: IGF-like family receptor 1 isoform X2 [Galeopterus variegatus]
ENSG00000126247(CAPNS1)	--	577.444752	9631	563.466425	8750	576.6861395	9188	599.2872482	9303	537.8705087	8714	548.0515865	8907	0.995525044	-0.080808722	normal	0.995582957	-0.027369721	normal	0.99566927	-0.053093829	normal	0.843370735	-0.055475625	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K08583|0|mcc:712561|calpain small subunit 1-like; K08583 calpain, small subunit 1 (A)"	--	[T]	Signal transduction mechanisms	EF-hand domain;; EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF hand	Calpain small subunit 1 GN=CAPNS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: calpain small subunit 1 [Leptonychotes weddellii]
ENSG00000126254(RBM42)	--	99.00794183	2955	105.3278808	3237	98.76534775	3068	114.8416821	3444	122.0129044	3631	103.9854003	3129	0.980681533	0.190003176	normal	0.986296972	0.144219365	normal	0.990381346	0.020101922	normal	0.579141436	0.118598143	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 42 GN=RBM42 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RNA-binding protein 42 isoform X4 [Sus scrofa]
ENSG00000126259(KIRREL2)	--	1.15067661	72	0.566452104	35	0.64389966	37	0.302489362	19	0.941605327	59	0.401514882	25	7.63E-05	-1.869628453	down	0.82792331	0.708130967	normal	0.959162034	-0.54654983	normal	0.656629899	-0.503992429	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Kin of IRRE-like protein 2 (Precursor) GN=KIRREL2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kin of IRRE-like protein 2 [Lipotes vexillifer]
ENSG00000126261(UBA2)	--	101.4999449	5970	102.9754549	5986	106.6418136	5957	99.52459773	5730	99.42893328	5558	87.01600689	4882	0.99315047	-0.090004409	normal	0.991533263	-0.128419322	normal	0.962847839	-0.295322145	normal	0.402135481	-0.169336246	normal	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	"K10685|0|hsa:10054|UBA2, ARX, SAE2; ubiquitin-like modifier activating enzyme 2; K10685 ubiquitin-like 1-activating enzyme E1 B [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	ThiF family;; Repeat in ubiquitin-activating (UBA) protein;; Ubiquitin/SUMO-activating enzyme ubiquitin-like domain;; Ubiquitin-activating enzyme active site	SUMO-activating enzyme subunit 2 GN=UBA2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: SUMO-activating enzyme subunit 2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000126262(FFAR2)	--	0.026235015	1	0	0	0	0	0	0	0	0	0.025922264	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04328|0|hsa:2867|FFAR2, FFA2R, GPR43; free fatty acid receptor 2; K04328 free fatty acid receptor 2 (A)"	cAMP signaling pathway (ko04024)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv	Free fatty acid receptor 2 GN=FFAR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: free fatty acid receptor 2-like [Tupaia chinensis] 
ENSG00000126264(HCST)	--	0.399408	2	2.014816	6	0.384413	1	0.573957	2	1.331561	4	1.288088	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K07988|2.46555e-21|ggo:101126290|HCST; hematopoietic cell signal transducer; K07988 hematopoietic cell signal transducer (A)	Natural killer cell mediated cytotoxicity (ko04650)	--	--	DAP10 membrane protein	Hematopoietic cell signal transducer (Precursor) GN=HCST OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: hematopoietic cell signal transducer isoform 1 [Ceratotherium simum simum]
ENSG00000126267(COX6B1)	--	434.5421998	3353	422.7239834	3274	461.4504258	3597	448.2015532	3546	430.0136956	3317	462.1452812	3641	0.990761	0.049885561	normal	0.990625832	-0.002600674	normal	0.991506226	0.009245276	normal	0.956289101	0.017991856	normal	--	--	--	K02267|6.77452e-60|ptr:745426|COX6B1; cytochrome c oxidase subunit 6B1; K02267 cytochrome c oxidase subunit 6b (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome oxidase c subunit VIb	Cytochrome c oxidase subunit 6B1 GN=COX6B1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: cytochrome c oxidase subunit 6B1 [Galeopterus variegatus]
ENSG00000126351(THRA)	--	16.569314	1250	12.11970017	929	13.84845442	1136	12.64108353	1035	14.00422997	1082	10.575752	853	0.903319781	-0.302719939	normal	0.958783955	0.198224213	normal	0.652874188	-0.42098758	normal	0.497534165	-0.180086652	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K05547|0|ggo:101143950|THRA; thyroid hormone receptor alpha isoform 1; K05547 thyroid hormone receptor alpha (A)	Neuroactive ligand-receptor interaction (ko04080);; Thyroid hormone signaling pathway (ko04919)	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Thyroid hormone receptor alpha GN=THRA OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: thyroid hormone receptor alpha isoform 1 [Ceratotherium simum simum]
ENSG00000126353(CCR7)	--	2.3712412	67	0.869280625	38	1.758498679	58	1.668108718	60	2.45730609	91	1.582692305	60	0.971068689	-0.185531953	normal	0.015132011	1.206502218	normal	0.976579829	0.039602883	normal	0.542395782	0.351699026	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04182|0|pps:100995275|CCR7; chemokine (C-C motif) receptor 7; K04182 C-C chemokine receptor type 7 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Transcriptional misregulation in cancer (ko05202)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	C-C chemokine receptor type 7 (Precursor) GN=CCR7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C-C chemokine receptor type 7 [Galeopterus variegatus]
ENSG00000126368(NR1D1)	--	8.71568	455	7.30615	376	7.46275	390	3.79453	195	3.80741	197	4.93188	259	3.49E-08	-1.246592894	down	0.000324789	-0.948597314	normal	0.185262435	-0.595957526	normal	5.47E-06	-0.927757582	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K03728|0|ptr:454644|NR1D1; nuclear receptor subfamily 1, group D, member 1; K03728 nuclear receptor subfamily 1 group D member 1 (A)"	Circadian rhythm (ko04710)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Nuclear receptor subfamily 1 group D member 1 GN=NR1D1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor subfamily 1 group D member 1 [Galeopterus variegatus]
ENSG00000126391(FRMD8)	--	14.5676207	829	14.34193138	947	16.9365231	902	13.76185383	807	13.43275931	793	18.94287659	919	0.975214911	-0.069505121	normal	0.919038717	-0.276986016	normal	0.978401646	0.018615066	normal	0.647474419	-0.109123057	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	FERM central domain	FERM domain-containing protein 8 GN=FRMD8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: FERM domain-containing protein 8 [Galeopterus variegatus]
ENSG00000126432(PRDX5)	--	305.98011	3881	311.5621	4103	294.5837	3945	295.79448	3805	282.92585	3522	291.1592	3749	0.991321561	-0.059340516	normal	0.973481634	-0.241614573	normal	0.990721955	-0.081778754	normal	0.544600153	-0.128334312	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K11187|1.2341e-139|hsa:25824|PRDX5, ACR1, AOEB166, B166, HEL-S-55, PLP, PMP20, PRDX6, PRXV, prx-V; peroxiredoxin 5 (EC:1.11.1.15); K11187 peroxiredoxin 5, atypical 2-Cys peroxiredoxin [EC:1.11.1.15] (A)"	Peroxisome (ko04146)	[O]	"Posttranslational modification, protein turnover, chaperones"	Redoxin;; AhpC/TSA family	"Peroxiredoxin-5, mitochondrial (Precursor) GN=PRDX5 OS=Homo sapiens (Human) PE=1 SV=4"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: peroxiredoxin-5, mitochondrial [Orycteropus afer afer]"
ENSG00000126453(BCL2L12)	--	44.7845209	746	33.69272959	598	35.184054	601	36.979694	606	32.8818709	545	36.39179902	602	0.858473445	-0.329934538	normal	0.960064716	-0.154905278	normal	0.973772781	-0.005878167	normal	0.469077809	-0.171347962	normal	--	--	--	--	--	--	--	--	Bcl-2-like protein 12 GN=BCL2L12 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: bcl-2-like protein 12 [Ovis aries]
ENSG00000126456(IRF3)	--	48.2339674	1284	41.08266501	1138	54.60286642	1316	44.1350781	1132	47.8848276	1265	37.43469176	997	0.958219449	-0.212332673	normal	0.974440856	0.131045044	normal	0.699802392	-0.408244735	normal	0.427757343	-0.160565592	normal	--	--	"Molecular Function: regulatory region DNA binding (GO:0000975);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K05411|0|hsa:3661|IRF3; interferon regulatory factor 3; K05411 interferon regulatory factor 3 (A)	Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; Pertussis (ko05133);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	--	--	Interferon regulatory factor transcription factor;; Interferon-regulatory factor 3	Interferon regulatory factor 3 GN=IRF3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: interferon regulatory factor 3 isoform X2 [Pteropus alecto]
ENSG00000126457(PRMT1)	--	177.1088515	4670	154.8709281	4230	167.8151235	4571	182.2385263	4919	178.6613536	4779	152.9175819	4042	0.992932936	0.044096106	normal	0.988099534	0.154572532	normal	0.984950278	-0.185666572	normal	0.985026733	0.006856521	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	K11434|0|ptr:456214|PRMT1; protein arginine methyltransferase 1; K11434 protein arginine N-methyltransferase 1 [EC:2.1.1.-] (A)	FoxO signaling pathway (ko04068)	[OKT]	"Posttranslational modification, protein turnover, chaperones;; Transcription;; Signal transduction mechanisms"	Methyltransferase domain;; Ribosomal protein L11 methyltransferase (PrmA);; Methyltransferase domain;; PRMT5 arginine-N-methyltransferase;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase small domain;; Met-10+ like-protein	Protein arginine N-methyltransferase 1 GN=PRMT1 OS=Homo sapiens (Human) PE=1 SV=2	KOT	"Transcription;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: protein arginine N-methyltransferase 1 isoform X1 [Galeopterus variegatus]
ENSG00000126458(RRAS)	--	94.9878	1592	80.1996	1389	85.6171	1494	63.2668	1082	68.9431	1155	49.5108	839	0.076166533	-0.587279861	normal	0.922148097	-0.287236796	normal	0.000120076	-0.839578738	normal	0.000123932	-0.56261386	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07829|9.23808e-133|hsa:6237|RRAS; related RAS viral (r-ras) oncogene homolog; K07829 Ras-related protein R-Ras (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Tight junction (ko04530);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein R-Ras (Precursor) GN=RRAS OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein R-Ras [Canis lupus familiaris] 
ENSG00000126460(PRRG2)	--	1.671276953	12	0.546560363	13	0.40919618	9	0.673295161	16	0.368876822	8	0.581858282	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain	Transmembrane gamma-carboxyglutamic acid protein 2 (Precursor) GN=PRRG2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: transmembrane gamma-carboxyglutamic acid protein 2 [Galeopterus variegatus]
ENSG00000126461(SCAF1)	--	54.44635413	6280	60.09198675	6569	57.08250142	6708	60.99997	6122	53.34136968	5777	54.87229031	5914	0.99392936	-0.067577032	normal	0.98636799	-0.206729037	normal	0.988378594	-0.189994237	normal	0.457997625	-0.155997859	normal	--	--	--	--	--	[R]	General function prediction only	--	"Splicing factor, arginine/serine-rich 19 GN=SCAF1 OS=Homo sapiens (Human) PE=1 SV=3"	K	Transcription	"Splicing factor, arginine/serine-rich 19 [Pteropus alecto]"
ENSG00000126467(TSKS)	--	0.025816542	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16492|0|hsa:60385|TSKS, PPP1R161, STK22S1, TSKS1, TSSKS; testis-specific serine kinase substrate; K16492 testis-specific serine kinase substrate (A)"	--	--	--	Testis-specific serine kinase substrate	Testis-specific serine kinase substrate GN=TSKS OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: testis-specific serine kinase substrate [Oryctolagus cuniculus]
ENSG00000126500(FLRT1)	--	0.368021579	30	0.572244	47	0.355614695	29	0.431529	36	0.237892009	19	0.53302018	44	0.981200168	0.221821583	normal	0.245283819	-1.262164652	normal	0.943608583	0.568917535	normal	0.906273435	-0.119906484	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K16362|0|hsa:23769|FLRT1, SPG68; fibronectin leucine rich transmembrane protein 1; K16362 leucine-rich repeat transmembrane protein FLRT (A)"	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Leucine-rich repeat transmembrane protein FLRT1 (Precursor) GN=FLRT1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: leucine-rich repeat transmembrane protein FLRT1 [Galeopterus variegatus] 
ENSG00000126522(ASL)	--	24.31875932	1147	22.6055556	1093	25.76429173	1170	26.8610229	1338	30.26459782	1455	24.90490404	1122	0.964696919	0.191143232	normal	0.765792725	0.390829088	normal	0.979466668	-0.068636693	normal	0.362483001	0.177724702	normal	[E]	Amino acid transport and metabolism	--	"K01755|0|hsa:435|ASL, ASAL; argininosuccinate lyase (EC:4.3.2.1); K01755 argininosuccinate lyase [EC:4.3.2.1] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Lyase;; Argininosuccinate lyase C-terminal	Argininosuccinate lyase GN=ASL OS=Homo sapiens (Human) PE=1 SV=4	E	Amino acid transport and metabolism	PREDICTED: argininosuccinate lyase-like isoform X2 [Tupaia chinensis]
ENSG00000126524(SBDS)	--	26.82941542	778	31.29841778	907	31.56331161	906	56.63631236	1664	46.77331333	1358	43.30771015	1261	5.38E-08	1.064510852	up	0.150120559	0.560114449	normal	0.46830817	0.468028779	normal	9.22E-05	0.703129106	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: ribosome biogenesis (GO:0042254);; 	K14574|2.23273e-171|ptr:463942|SBDS; Shwachman-Bodian-Diamond syndrome; K14574 ribosome maturation protein SDO1 (A)	Ribosome biogenesis in eukaryotes (ko03008)	[J]	"Translation, ribosomal structure and biogenesis"	SBDS protein C-terminal domain;; Shwachman-Bodian-Diamond syndrome (SBDS) protein	Ribosome maturation protein SBDS GN=SBDS OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosome maturation protein SBDS [Equus caballus] 
ENSG00000126561(STAT5A)	--	0.861524485	54	1.040867	63	0.557233	50	1.903807	168	2.125236	186	2.398255353	213	3.07E-07	1.579822086	up	3.55E-07	1.518250217	up	3.40E-13	2.049931252	up	3.93E-09	1.742724378	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K11223|0|hsa:6776|STAT5A, MGF, STAT5; signal transducer and activator of transcription 5A; K11223 signal transducer and activator of transcription 5A (A)"	ErbB signaling pathway (ko04012);; Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917);; Hepatitis B (ko05161);; Measles (ko05162);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221)	[KT]	Transcription;; Signal transduction mechanisms	"STAT protein, DNA binding domain;; STAT protein, all-alpha domain;; STAT protein, protein interaction domain;; SH2 domain"	Signal transducer and activator of transcription 5A GN=STAT5A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: signal transducer and activator of transcription 5A isoform X1 [Ailuropoda melanoleuca] 
ENSG00000126562(WNK4)	--	0.789788474	60	0.974822993	77	0.94301758	70	1.00824072	79	1.1777456	87	1.189459	94	0.947001517	0.358047259	normal	0.96696891	0.151922122	normal	0.919344393	0.409357058	normal	0.566439982	0.308215095	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08867|0|hsa:65266|WNK4, PHA2B, PRKWNK4; WNK lysine deficient protein kinase 4 (EC:2.7.11.1); K08867 WNK lysine deficient protein kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Oxidative-stress-responsive kinase 1 C terminal	Serine/threonine-protein kinase WNK4 GN=WNK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase WNK4 [Tupaia chinensis]
ENSG00000126581(BECN1)	--	32.61622657	1298	36.5290268	1416	35.41614416	1365	37.908729	1404	35.6892884	1375	37.39297276	1510	0.980607042	0.08232658	normal	0.981563776	-0.063747111	normal	0.976649057	0.137211568	normal	0.845432446	0.051431541	normal	--	--	Biological Process: autophagy (GO:0006914);; 	"K08334|0|hsa:8678|BECN1, ATG6, VPS30, beclin1; beclin 1, autophagy related; K08334 beclin 1 (A)"	Regulation of autophagy (ko04140)	[T]	Signal transduction mechanisms	"Autophagy protein Apg6;; Beclin-1 BH3 domain, Bcl-2-interacting"	Beclin-1 GN=BECN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: beclin-1 isoform X1 [Loxodonta africana]
ENSG00000126583(PRKCG)	--	2.821953558	204	1.632582435	115	1.881760696	136	0.282867308	20	0.710601442	50	0.88159439	61	0	-3.284157755	down	0.003389945	-1.198466577	down	0.002293892	-1.145494383	down	0.000802022	-1.814664281	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K02677|0|hsa:5582|PRKCG, PKC-gamma, PKCC, PKCG, SCA14; protein kinase C, gamma (EC:2.7.11.13); K02677 classical protein kinase C [EC:2.7.11.13] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; HIF-1 signaling pathway (ko04066);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Tight junction (ko04530);; Gap junction (ko04540);; Natural killer cell mediated cytotoxicity (ko04650);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Vibrio cholerae infection (ko05110);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Hepatitis B (ko05161);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2 domain;; Protein kinase C terminal domain	Protein kinase C gamma type GN=PRKCG OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	protein kinase C gamma type (predicted) [Rhinolophus ferrumequinum]
ENSG00000126602(TRAP1)	--	73.67706654	3295	62.00149901	2881	68.8419336	3183	83.49065508	3568	78.58274897	3499	55.96296679	2565	0.989817385	0.083967257	normal	0.964597622	0.258823004	normal	0.924756498	-0.319550301	normal	0.959389613	0.019491024	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: protein folding (GO:0006457);; Biological Process: response to stress (GO:0006950);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K09488|0|ggo:101142976|TRAP1; heat shock protein 75 kDa, mitochondrial isoform 1; K09488 TNF receptor-associated protein 1 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Hsp90 protein;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	"Heat shock protein 75 kDa, mitochondrial (Precursor) GN=TRAP1 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: heat shock protein 75 kDa, mitochondrial [Equus przewalskii]"
ENSG00000126603(GLIS2)	--	17.369695	1302	18.481146	1437	17.775701	1402	19.270354	1465	18.967098	1417	19.018109	1478	0.975790604	0.139184058	normal	0.982581911	-0.041602771	normal	0.982165094	0.067797246	normal	0.839072869	0.05319464	normal	[R]	General function prediction only	--	K09233|0|ptr:467893|GLIS2; GLIS family zinc finger 2; K09233 zinc finger protein GLIS2 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type"	Zinc finger protein GLIS2 GN=GLIS2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein GLIS2 [Canis lupus familiaris]
ENSG00000126653(NSRP1)	--	16.98082416	936	15.03835588	891	17.35826843	1017	15.71857002	840	14.17070711	828	14.7154465	774	0.959870735	-0.186627869	normal	0.970130066	-0.126997553	normal	0.713645238	-0.401519042	normal	0.205321542	-0.241072396	normal	--	--	--	K13206|0|pps:100968785|NSRP1; nuclear speckle splicing regulatory protein 1; K13206 coiled-coil domain-containing protein 55 (A)	--	[S]	Function unknown	Coiled-coil domain-containing protein 55 (DUF2040)	Nuclear speckle splicing regulatory protein 1 GN=NSRP1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: nuclear speckle splicing regulatory protein 1 isoform X1 [Loxodonta africana]
ENSG00000126698(DNAJC8)	--	35.65667096	1281	36.99582023	1343	34.41612665	1222	36.08379302	1291	40.52265462	1430	34.28349233	1242	0.982269758	-0.019590334	normal	0.981241092	0.069053923	normal	0.981895011	0.015110897	normal	0.945365239	0.021862116	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09528|1.60923e-156|pps:100986391|DNAJC8; DnaJ (Hsp40) homolog, subfamily C, member 8; K09528 DnaJ homolog subfamily C member 8 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 8 GN=DNAJC8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 8 [Ochotona princeps]
ENSG00000126705(AHDC1)	--	6.044644838	786	6.239683443	812	6.464631208	869	4.725902094	609	4.170326493	544	3.130897756	409	0.722311209	-0.398032646	normal	0.09353216	-0.597929385	normal	1.33E-07	-1.092708222	down	2.70E-05	-0.681542814	normal	--	--	--	--	--	--	--	--	AT-hook DNA-binding motif-containing protein 1 GN=AHDC1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: AT-hook DNA-binding motif-containing protein 1 [Galeopterus variegatus] 
ENSG00000126709(IFI6)	--	13.590636	130	12.69935274	127	11.538278	115	12.58905365	121	17.523881	167	12.41723378	120	0.963919203	-0.132710556	normal	0.886274582	0.369743134	normal	0.968710546	0.052434061	normal	0.835015996	0.11203991	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced 6-16 family	Interferon alpha-inducible protein 6 (Precursor) GN=IFI6 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: interferon alpha-inducible protein 6 [Tupaia chinensis] 
ENSG00000126733(DACH2)	--	0	0	0	0	0	0	0	0	0	0	0.024422523	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	SKI/SNO/DAC family	Dachshund homolog 2 GN=DACH2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: dachshund homolog 2 isoform 1 [Trichechus manatus latirostris]
ENSG00000126746(ZNF384)	--	19.68901851	1076	21.9804876	1140	21.75282337	1161	16.69271504	938	18.91022812	968	23.050668	1293	0.948516629	-0.228500701	normal	0.93639867	-0.257010955	normal	0.973074544	0.146881488	normal	0.740153732	-0.098285347	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Drought induced 19 protein (Di19), zinc-binding"	Zinc finger protein 384 GN=ZNF384 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 384 isoform X2 [Mustela putorius furo] 
ENSG00000126749(EMG1)	--	9.18607	739	8.357536	731	9.324727	702	14.51508	1024	10.64676	820	11.248171	911	0.586049595	0.438958917	normal	0.966166919	0.144044474	normal	0.798472694	0.366992704	normal	0.072332862	0.321308407	normal	[S]	Function unknown	Molecular Function: methyltransferase activity (GO:0008168);; 	"K14568|8.41555e-180|hsa:10436|EMG1, C2F, Grcc2f, NEP1; EMG1 N1-specific pseudouridine methyltransferase; K14568 rRNA small subunit pseudouridine methyltransferase Nep1 [EC:2.1.1.260] (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[J]	"Translation, ribosomal structure and biogenesis"	EMG1/NEP1 methyltransferase	Ribosomal RNA small subunit methyltransferase NEP1 {ECO:0000305|PubMed:20047967} OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosomal RNA small subunit methyltransferase NEP1 [Elephantulus edwardii]
ENSG00000126752(SSX1)	--	0	0	0	0	0.0413288	0	0	0	0	0	0.0823553	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15624|3.24326e-118|hsa:6756|SSX1, CT5.1, SSRC; synovial sarcoma, X breakpoint 1; K15624 protein SSX1 (A)"	Transcriptional misregulation in cancer (ko05202)	--	--	SSXRD motif	Protein SSX1 GN=SSX1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: protein SSX1-like [Ursus maritimus]
ENSG00000126756(UXT)	--	95.69872	555	75.13188	451	86.1168	540	90.06989	556	96.68041	557	93.07667	569	0.972477157	-0.028157274	normal	0.906797249	0.282270305	normal	0.970901024	0.066995009	normal	0.72414429	0.100689639	normal	--	--	--	--	--	[K]	Transcription	Prefoldin subunit	Protein UXT GN=UXT OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein UXT isoform X1 [Galeopterus variegatus]
ENSG00000126759(CFP)	--	0.165566515	5	0.078175008	3	0.409423234	15	0.052948776	2	0.291346108	5	0.135458648	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15412|0|hsa:5199|CFP, BFD, PFC, PFD, PROPERDIN; complement factor properdin; K15412 complement factor properdin (A)"	Herpes simplex infection (ko05168)	[RP]	General function prediction only;; Inorganic ion transport and metabolism	Thrombospondin type 1 domain	Properdin (Precursor) GN=CFP OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: properdin [Galeopterus variegatus]
ENSG00000126767(ELK1)	--	21.745217	975	22.903883	990	25.06224	1095	20.325765	918	17.93937	774	23.91622	1039	0.973042561	-0.117549379	normal	0.787245804	-0.375870337	normal	0.977683188	-0.083907676	normal	0.358050664	-0.184798297	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K04375|0|hsa:2002|ELK1; ELK1, member of ETS oncogene family; K04375 ETS domain-containing protein Elk-1 (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Focal adhesion (ko04510);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Oxytocin signaling pathway (ko04921);; Prion diseases (ko05020);; Leishmaniasis (ko05140);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Proteoglycans in cancer (ko05205);; Endometrial cancer (ko05213)	[K]	Transcription	Ets-domain	ETS domain-containing protein Elk-1 GN=ELK1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS domain-containing protein Elk-1 isoform X1 [Leptonychotes weddellii] 
ENSG00000126768(TIMM17B)	--	59.484012	800	61.92519648	856	59.61671506	836	52.60068337	724	52.8110091	703	63.393901	868	0.960374038	-0.174490095	normal	0.892741547	-0.304917142	normal	0.976929802	0.045819312	normal	0.542950373	-0.139476836	normal	--	--	--	"K17795|2.26506e-161|hsa:10245|TIMM17B, DXS9822, TIM17B; translocase of inner mitochondrial membrane 17 homolog B (yeast); K17795 mitochondrial import inner membrane translocase subunit TIM17 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim17/Tim22/Tim23/Pmp24 family	Mitochondrial import inner membrane translocase subunit Tim17-B GN=TIMM17B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim17-B [Odobenus rosmarus divergens]
ENSG00000126773(PCNX4)	--	17.43492387	1381	17.89762641	1431	17.99650733	1404	21.515685	1687	21.33993703	1676	23.30614199	1791	0.945304813	0.257654696	normal	0.965031516	0.20637023	normal	0.868394104	0.342603458	normal	0.113952923	0.268789794	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Pecanex protein (C-terminus)	Pecanex-like protein 4 GN=PCNXL4 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: pecanex-like protein 4 [Ursus maritimus] 
ENSG00000126775(ATG14)	--	4.33505	362	4.99928	418	4.18451	346	4.52432	379	6.29699	523	5.58427	467	0.968547614	0.035229754	normal	0.891565863	0.300906451	normal	0.69029596	0.422762875	normal	0.303174135	0.261188089	normal	--	--	Biological Process: positive regulation of autophagy (GO:0010508);; 	"K17889|0|hsa:22863|ATG14, ATG14L, BARKOR, KIAA0831; autophagy related 14; K17889 beclin 1-associated autophagy-related key regulator (A)"	Regulation of autophagy (ko04140)	[R]	General function prediction only	UV radiation resistance protein and autophagy-related subunit 14	Beclin 1-associated autophagy-related key regulator GN=ATG14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: beclin 1-associated autophagy-related key regulator [Balaenoptera acutorostrata scammoni]
ENSG00000126777(KTN1)	--	69.233867	7619	74.80191928	8118	78.37422654	8517	71.01805764	7818	67.92269515	7401	64.75491503	7011	0.995380639	0.006364399	normal	0.992202014	-0.154800466	normal	0.973584205	-0.288959912	normal	0.503145036	-0.147102429	normal	--	--	--	K17975|0|pps:100985417|KTN1; kinectin 1 (kinesin receptor); K17975 kinectin (A)	--	--	--	--	Kinectin GN=KTN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: kinectin isoform 1 [Orcinus orca]
ENSG00000126778(SIX1)	--	2.857058299	145	3.046311301	171	3.986980516	208	3.27244537	210	3.952623	239	4.057812	233	0.672549714	0.499087963	normal	0.725376852	0.45814619	normal	0.95657096	0.154393874	normal	0.245429442	0.359848897	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K15614|0|ptr:452952|SIX1; SIX homeobox 1; K15614 homeobox protein SIX1 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Homeobox domain;; Homeobox KN domain	Homeobox protein SIX1 GN=SIX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	homeobox protein SIX1 [Sus scrofa] 
ENSG00000126785(RHOJ)	--	0	0	0	0	0	0	0	0	0.0319114	1	0.0324817	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07864|3.0078e-158|pps:100991266|RHOJ; ras homolog family member J; K07864 Ras homolog gene family, member J (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoJ (Precursor) GN=RHOJ OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoJ [Condylura cristata]
ENSG00000126787(DLGAP5)	--	23.55410302	1464	22.85201813	1407	25.28996	1544	21.617201	1356	21.97052706	1360	20.09850884	1255	0.975827335	-0.141236567	normal	0.981160975	-0.070365303	normal	0.906690422	-0.30694274	normal	0.368620768	-0.174168239	normal	--	--	Biological Process: signaling (GO:0023052);; 	"K16804|0|pps:100988224|DLGAP5; discs, large (Drosophila) homolog-associated protein 5; K16804 disks large-associated protein 5 (A)"	--	[T]	Signal transduction mechanisms	Guanylate-kinase-associated protein (GKAP) protein	Disks large-associated protein 5 GN=DLGAP5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: disks large-associated protein 5 [Galeopterus variegatus]
ENSG00000126790(L3HYPDH)	--	21.18850478	880	19.470935	886	21.73481146	773	23.62471843	923	25.8481346	952	24.56534847	1058	0.977779221	0.037930197	normal	0.975378993	0.082093124	normal	0.568466838	0.443762856	normal	0.35879938	0.187100302	normal	[E]	Amino acid transport and metabolism	--	"K18384|0|hsa:112849|L3HYPDH, C14orf149; L-3-hydroxyproline dehydratase (trans-) (EC:4.2.1.77); K18384 trans-L-3-hydroxyproline dehydratase [EC:4.2.1.77] (A)"	Arginine and proline metabolism (ko00330)	--	--	Proline racemase	Trans-L-3-hydroxyproline dehydratase GN=L3HYPDH OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: trans-L-3-hydroxyproline dehydratase [Ceratotherium simum simum]
ENSG00000126803(HSPA2)	--	51.15293768	2974	46.08021857	2716	48.27250018	2863	18.0381532	1050	21.86445915	1276	20.8724294	1233	0	-1.531452683	down	6.57E-09	-1.110357304	down	2.52E-11	-1.222632504	down	1.89E-22	-1.285585218	down	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	K03283|0|nle:100600172|HSPA2; heat shock 70kDa protein 2; K03283 heat shock 70kDa protein 1/8 (A)	Spliceosome (ko03040);; MAPK signaling pathway (ko04010);; Protein processing in endoplasmic reticulum (ko04141);; Endocytosis (ko04144);; Antigen processing and presentation (ko04612);; Estrogen signaling pathway (ko04915);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Measles (ko05162);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Hsp70 protein;; MreB/Mbl protein;; FGGY family of carbohydrate kinases, C-terminal domain"	Heat shock-related 70 kDa protein 2 GN=HSPA2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock-related 70 kDa protein 2 [Felis catus] 
ENSG00000126804(ZBTB1)	--	12.617967	673	17.501067	1004	11.570331	638	10.261098	585	12.028602	643	17.16745	888	0.938201697	-0.232432396	normal	0.022122704	-0.663036249	normal	0.478313347	0.467767865	normal	0.800675307	-0.150165955	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10488|0|hsa:22890|ZBTB1, ZNF909; zinc finger and BTB domain containing 1; K10488 zinc finger and BTB domain-containing protein 1 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; C2H2-type zinc finger;; Zinc finger, C2H2 type;; Zinc-finger double domain"	Zinc finger and BTB domain-containing protein 1 GN=ZBTB1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	zinc finger and BTB domain-containing protein 1 [Bos taurus] 
ENSG00000126814(TRMT5)	--	7.389356488	465	6.162093	484	9.66466	470	6.650363024	522	8.631173654	572	9.012571129	531	0.962314289	0.135563921	normal	0.94143773	0.218951648	normal	0.956707406	0.167253075	normal	0.489744752	0.174447676	normal	[R]	General function prediction only	--	"K15429|0|hsa:57570|TRMT5, KIAA1393, TRM5; tRNA methyltransferase 5 (EC:2.1.1.228); K15429 tRNA (guanine37-N1)-methyltransferase [EC:2.1.1.228] (A)"	--	[A]	RNA processing and modification	Met-10+ like-protein	tRNA (guanine(37)-N1)-methyltransferase {ECO:0000255|HAMAP-Rule:MF_03152} OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (guanine(37)-N1)-methyltransferase [Equus caballus]
ENSG00000126821(SGPP1)	--	20.8275	874	19.34132	823	19.56097	818	22.29062	950	20.38871	866	19.40574	828	0.975204097	0.089311358	normal	0.975993694	0.051954965	normal	0.977326536	0.009221537	normal	0.85979673	0.050490848	normal	[I]	Lipid transport and metabolism	--	"K04716|0|hsa:81537|SGPP1, SPPase1; sphingosine-1-phosphate phosphatase 1; K04716 sphingosine-1-phosphate phosphatase 1 [EC:3.1.3.-] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[I]	Lipid transport and metabolism	PAP2 superfamily	Sphingosine-1-phosphate phosphatase 1 GN=SGPP1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: sphingosine-1-phosphate phosphatase 1 [Leptonychotes weddellii]
ENSG00000126822(PLEKHG3)	--	12.97854836	823	13.053432	813	15.06108656	937	18.37034186	973	15.527531	1012	14.0905322	821	0.952978606	0.210353634	normal	0.90678549	0.293964529	normal	0.95653118	-0.198615542	normal	0.667173379	0.103694334	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	--	--	RhoGEF domain;; PH domain	Pleckstrin homology domain-containing family G member 3 GN=PLEKHG3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family G member 3 [Tupaia chinensis]
ENSG00000126858(RHOT1)	--	21.81684665	1086	22.13287798	1096	25.04393546	1229	20.820215	1035	16.520167	814	18.46522002	958	0.976294054	-0.100080537	normal	0.561239066	-0.449850501	normal	0.806075156	-0.36716569	normal	0.079423318	-0.302483451	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07870|0|ptr:454570|RHOT1; ras homolog family member T1; K07870 Ras homolog gene family, member T1 (A)"	--	[V]	Defense mechanisms	Miro-like protein;; EF hand associated;; EF hand associated;; Ras family;; 50S ribosome-binding GTPase;; ADP-ribosylation factor family;; EF-hand domain;; Signal recognition particle receptor beta subunit;; Ethanolamine utilisation - propanediol utilisation	Mitochondrial Rho GTPase 1 GN=RHOT1 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: mitochondrial Rho GTPase 1 isoform X1 [Condylura cristata]
ENSG00000126860(EVI2A)	--	1.7270425	59	1.525422	46	2.99119	98	1.646399	55	0.697435	20	2.353774663	82	0.975481929	-0.12864479	normal	0.40104243	-1.163472234	normal	0.954533113	-0.261039558	normal	0.72460536	-0.389540775	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Ectropic viral integration site 2A protein (EVI2A)	Protein EVI2A (Precursor) GN=EVI2A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein EVI2A [Galeopterus variegatus]
ENSG00000126861(OMG)	--	0.0907783	3	0.0311624	1	0.0616082	1	0.0606808	2	0.0292905	0	0.17948	6	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K16666|0|ptr:748467|OMG; oligodendrocyte myelin glycoprotein; K16666 oligodendrocyte myelin glycoprotein (A)	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain;; Leucine Rich repeat	Oligodendrocyte-myelin glycoprotein (Precursor) GN=OMG OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: oligodendrocyte-myelin glycoprotein [Canis lupus familiaris]
ENSG00000126870(WDR60)	--	6.0868197	572	7.135014	607	6.810325	567	9.990284	605	6.311932	510	5.00936621	469	0.972345038	0.049957251	normal	0.914905936	-0.271885757	normal	0.907543698	-0.28122622	normal	0.516025214	-0.162560307	normal	--	--	--	--	--	[Z]	Cytoskeleton	"WD domain, G-beta repeat"	WD repeat-containing protein 60 GN=WDR60 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: WD repeat-containing protein 60 [Galeopterus variegatus]
ENSG00000126878(AIF1L)	--	1.258514735	81	0.993573214	64	1.018674052	64	0.76817927	39	0.817221569	48	0.565520062	38	0.105018469	-1.055772173	normal	0.941344917	-0.424830956	normal	0.769760635	-0.737501213	normal	0.112945433	-0.762886398	normal	--	--	--	"K18617|2.1515e-126|hsa:83543|AIF1L, C9orf58, IBA2; allograft inflammatory factor 1-like; K18617 allograft inflammatory factor 1 (A)"	--	[T]	Signal transduction mechanisms	--	Allograft inflammatory factor 1-like GN=AIF1L OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: allograft inflammatory factor 1-like isoform X2 [Canis lupus familiaris]
ENSG00000126882(FAM78A)	--	0.4885293	44	0.38117592	35	0.45286183	43	0.236178033	22	0.135176046	12	0.286107512	27	0.705111588	-0.981430238	normal	0.309580327	-1.45389421	normal	0.92605804	-0.650550549	normal	0.075296859	-1.020538753	normal	--	--	--	--	--	--	--	--	Protein FAM78A GN=FAM78A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM78A [Felis catus]
ENSG00000126883(NUP214)	--	14.63409241	2000	16.38517561	2227	16.10607732	2234	14.75441645	1965	14.75263873	2008	14.0946621	2024	0.985953599	-0.056259347	normal	0.977482002	-0.170646742	normal	0.980406838	-0.150604181	normal	0.536264224	-0.128529519	normal	--	--	--	"K14317|0|hsa:8021|NUP214, CAIN, CAN, D9S46E, N214, p250; nucleoporin 214kDa; K14317 nuclear pore complex protein Nup214 (A)"	RNA transport (ko03013);; Epstein-Barr virus infection (ko05169)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	--	Nuclear pore complex protein Nup214 GN=NUP214 OS=Homo sapiens (Human) PE=1 SV=2	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore complex protein Nup214 isoform X1 [Galeopterus variegatus]
ENSG00000126895(AVPR2)	--	0.116941375	3	0	0	0	0	0	0	0.119001347	2	0.163196225	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04228|0|hsa:554|AVPR2, ADHR, DI1, DIR, DIR3, NDI, V2R; arginine vasopressin receptor 2; K04228 arginine vasopressin receptor 2 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Vasopressin-regulated water reabsorption (ko04962)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Vasopressin V2 receptor GN=AVPR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vasopressin V2 receptor isoform 3 [Odobenus rosmarus divergens]
ENSG00000126903(SLC10A3)	--	17.60517168	583	16.1298941	548	15.599418	541	17.22515542	548	14.77416539	480	14.73632511	493	0.96606688	-0.119826451	normal	0.943716116	-0.211942554	normal	0.961941712	-0.141916652	normal	0.535298568	-0.158176023	normal	[R]	General function prediction only	Cellular Component: membrane (GO:0016020);; 	"K14343|0|cjc:100387617|SLC10A3; solute carrier family 10, member 3; K14343 solute carrier family 10 (sodium/bile acid cotransporter), member 3/5 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium Bile acid symporter family	P3 protein GN=SLC10A3 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: P3 protein isoform X1 [Leptonychotes weddellii]
ENSG00000126934(MAP2K2)	--	104.9591969	3355	87.37699648	2884	93.54242471	3136	81.460962	2677	83.96086758	2735	113.0786006	3730	0.884078471	-0.356344742	normal	0.987276231	-0.097904163	normal	0.971203554	0.241851564	normal	0.882681313	-0.056473374	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04369|0|ptr:456390|MAP2K2; mitogen-activated protein kinase kinase 2; K04369 mitogen-activated protein kinase kinase 2 [EC:2.7.12.2] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Toll-like receptor signaling pathway (ko04620);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Prion diseases (ko05020);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Dual specificity mitogen-activated protein kinase kinase 2 GN=MAP2K2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual specificity mitogen-activated protein kinase kinase 2 [Orcinus orca] 
ENSG00000126945(HNRNPH2)	--	2111.249049	6998	1987.295448	6888	2044.140297	7108	2318.626137	8460	2246.861344	7453	2086.561488	7436	0.984109078	0.242834189	normal	0.993928865	0.092290077	normal	0.994778884	0.056779835	normal	0.554530487	0.131810888	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12898|0|ptr:465762|HNRNPH2, HNRPH2; heterogeneous nuclear ribonucleoprotein H2 (H'); K12898 heterogeneous nuclear ribonucleoprotein F/H (A)"	--	[A]	RNA processing and modification	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNPHF zinc finger;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed GN=HNRNPH2 OS=Homo sapiens (Human) PE=1 SV=1"	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein H2 isoform X1 [Equus caballus] 
ENSG00000126947(ARMCX1)	--	0.122974	5	0.0482898	2	0.0962782	3	0.900187	37	0.976668	39	0.9249	38	0.001004849	2.533049394	up	3.71E-06	3.511469134	up	3.02E-05	3.123627484	up	4.42E-08	3.48979786	up	--	--	--	--	--	--	--	Armadillo-like;; Armadillo/beta-catenin-like repeat	Armadillo repeat-containing X-linked protein 1 GN=ARMCX1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing X-linked protein 1-like [Odobenus rosmarus divergens]
ENSG00000126953(TIMM8A)	--	11.12898	302	12.91041	358	12.15442	334	8.88179	249	10.2061	284	8.84029	246	0.895689111	-0.307508921	normal	0.843587304	-0.353812991	normal	0.676586735	-0.447112879	normal	0.136907442	-0.372786304	normal	--	--	--	K17780|1.72977e-60|ptr:738690|TIMM8A; translocase of inner mitochondrial membrane 8 homolog A (yeast); K17780 mitochondrial import inner membrane translocase subunit TIM8 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim10/DDP family zinc finger	Mitochondrial import inner membrane translocase subunit Tim8 A GN=TIMM8A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim8 A [Myotis lucifugus] 
ENSG00000126970(ZC4H2)	--	5.370605898	218	4.087058414	164	4.314089331	174	8.346139455	339	7.371893362	298	6.185889155	251	0.208949091	0.602693848	normal	0.008420836	0.834402277	normal	0.56632087	0.516550661	normal	0.00661783	0.653283589	normal	--	--	--	--	--	[S]	Function unknown	Zinc finger-containing protein	Zinc finger C4H2 domain-containing protein GN=ZC4H2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger C4H2 domain-containing protein isoformX1 [Canis lupus familiaris]
ENSG00000127022(CANX)	--	207.9843053	16643	214.5753149	17433	215.8858513	16985	276.5840981	22219	242.5617878	19283	276.0927212	21932	0.950675716	0.38601518	normal	0.996757466	0.124071865	normal	0.966324306	0.360456402	normal	0.141097308	0.291727436	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: protein folding (GO:0006457);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K08054|0|hsa:821|CANX, CNX, IP90, P90; calnexin; K08054 calnexin (A)"	Protein processing in endoplasmic reticulum (ko04141);; Phagosome (ko04145);; Antigen processing and presentation (ko04612);; Thyroid hormone synthesis (ko04918);; HTLV-I infection (ko05166)	[O]	"Posttranslational modification, protein turnover, chaperones"	Calreticulin family	Calnexin (Precursor) GN=CANX OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: calnexin [Galeopterus variegatus]
ENSG00000127054(INTS11)	--	22.322836	915	19.62156653	769	20.44204151	852	20.99007628	854	21.76575259	922	19.82430096	794	0.970548587	-0.130141667	normal	0.940045905	0.239925204	normal	0.972098816	-0.109803924	normal	0.999854936	-0.002070612	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K13148|0|hsa:54973|CPSF3L, CPSF73L, INT11, INTS11, RC-68, RC68; cleavage and polyadenylation specific factor 3-like (EC:3.1.27.-); K13148 integrator complex subunit 11 [EC:3.1.27.-] (A)"	--	[A]	RNA processing and modification	Beta-Casp domain;; Metallo-beta-lactamase superfamily;; RNA-metabolising metallo-beta-lactamase;; Beta-lactamase superfamily domain;; Beta-lactamase superfamily domain	Integrator complex subunit 11 GN=CPSF3L OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: integrator complex subunit 11 [Tupaia chinensis]
ENSG00000127080(IPPK)	--	5.645494	390	4.870595	384	6.12711	404	6.935655	511	6.80064	509	6.33886	426	0.821188674	0.357782405	normal	0.778740429	0.383816042	normal	0.968008253	0.067958939	normal	0.236761312	0.274127028	normal	--	--	Molecular Function: ATP binding (GO:0005524);; Molecular Function: inositol pentakisphosphate 2-kinase activity (GO:0035299);; 	"K10572|0|hsa:64768|IPPK, C9orf12, INSP5K2, IP5K, IPK1, bA476B13.1; inositol 1,3,4,5,6-pentakisphosphate 2-kinase (EC:2.7.1.158); K10572 inositol-pentakisphosphate 2-kinase [EC:2.7.1.158] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	Inositol-pentakisphosphate 2-kinase	Inositol-pentakisphosphate 2-kinase GN=IPPK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inositol-pentakisphosphate 2-kinase isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000127081(ZNF484)	--	1.82690441	204	2.012803949	224	1.419597132	159	1.171408718	163	2.095075612	184	1.45590907	169	0.883496943	-0.351560065	normal	0.908877863	-0.302958676	normal	0.965348382	0.07897635	normal	0.588074224	-0.207539743	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100980576|ZNF484; zinc finger protein 484; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zinc-finger of C2H2 type"	Zinc finger protein 484 GN=ZNF484 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 484-like [Ceratotherium simum simum]
ENSG00000127083(OMD)	--	0	0	0	0	0	0	0.078546	3	0.0508429	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08124|0|hsa:4958|OMD, OSAD, SLRR2C; osteomodulin; K08124 osteomodulin (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat N-terminal domain	Osteomodulin (Precursor) GN=OMD OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: osteomodulin [Galeopterus variegatus]
ENSG00000127084(FGD3)	--	0.154518634	12	0.15181959	12	0.148069354	11	0.1673262	13	0.075008346	5	0.038194522	3	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Molecular Function: metal ion binding (GO:0046872);; 	"K05722|0|hsa:89846|FGD3, ZFYVE5; FYVE, RhoGEF and PH domain containing 3; K05722 FYVE, RhoGEF and PH domain containing 3 (A)"	Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; FYVE zinc finger	"FYVE, RhoGEF and PH domain-containing protein 3 GN=FGD3 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: FYVE, RhoGEF and PH domain-containing protein 3 [Galeopterus variegatus]"
ENSG00000127124(HIVEP3)	--	0.419707688	120	0.166754247	47	0.395463214	112	0.67580013	190	0.585094539	168	0.327671276	95	0.382467655	0.625716072	normal	7.43E-09	1.7839707	up	0.953660636	-0.242235186	normal	0.304367836	0.676935239	normal	--	--	--	"K09239|0|hsa:59269|HIVEP3, KBP-1, KBP1, KRC, SHN3, Schnurri-3, ZAS3, ZNF40C; human immunodeficiency virus type I enhancer binding protein 3; K09239 human immunodeficiency virus type I enhancer-binding protein (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger"	Transcription factor HIVEP3 GN=HIVEP3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: transcription factor HIVEP3 [Galeopterus variegatus]
ENSG00000127125(PPCS)	--	31.641634	496	32.80033	535	29.650732	490	29.797282	478	31.913163	540	33.14537	517	0.968215647	-0.083897004	normal	0.971793515	-0.00798358	normal	0.969763666	0.068884099	normal	0.986272296	-0.007798007	normal	[H]	Coenzyme transport and metabolism	--	K01922|0|pps:100969367|PPCS; phosphopantothenoylcysteine synthetase; K01922 phosphopantothenate-cysteine ligase [EC:6.3.2.5] (A)	Pantothenate and CoA biosynthesis (ko00770)	[R]	General function prediction only	DNA / pantothenate metabolism flavoprotein	Phosphopantothenate--cysteine ligase GN=PPCS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: phosphopantothenate--cysteine ligase [Condylura cristata]
ENSG00000127129(EDN2)	--	0.743232	14	0.501892	10	0.554929545	9	1.960497	38	1.435005	27	1.129558	21	0.426260555	1.318816782	normal	0.757322491	1.288958606	normal	0.932353947	1.091219486	normal	0.032394393	1.358417775	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: regulation of vasoconstriction (GO:0019229);; 	K16367|6.90803e-117|pps:100976668|EDN2; endothelin 2; K16367 endothelin-2 (A)	--	--	--	Endothelin family	Endothelin-2 (Precursor) GN=EDN2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: endothelin-2 [Pteropus alecto]
ENSG00000127152(BCL11B)	--	0.200031889	21	0.060643985	7	0.049887224	5	0.313513051	39	0.375696795	45	0.282543338	24	0.890204194	0.817761923	normal	0.000201149	2.430819004	up	0.269637172	1.962873105	normal	0.009101198	1.687025303	up	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger"	B-cell lymphoma/leukemia 11B GN=BCL11B OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: B-cell lymphoma/leukemia 11B isoform 1 [Odobenus rosmarus divergens]
ENSG00000127184(COX7C)	--	355.92879	2290	378.465247	2442	353.7042439	2312	384.62949	2511	360.44237	2281	385.51015	2529	0.985823627	0.10201679	normal	0.984218827	-0.119746562	normal	0.984675243	0.121058464	normal	0.900535826	0.034380296	normal	--	--	--	K02272|7.01775e-40|ptr:739452|COX7C; cytochrome c oxidase subunit VIIc (EC:1.9.3.1); K02272 cytochrome c oxidase subunit 7c (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome c oxidase subunit VIIc	"Cytochrome c oxidase subunit 7C, mitochondrial (Precursor) GN=COX7C OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: cytochrome c oxidase subunit 7C, mitochondrial-like isoform X1 [Physeter catodon] "
ENSG00000127191(TRAF2)	--	22.9929632	891	22.25655105	936	24.98488013	1049	24.968121	1122	22.246381	955	24.81184039	1077	0.900816832	0.301279282	normal	0.978399924	0.007553564	normal	0.979998696	0.029669915	normal	0.627955357	0.111978326	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K03173|0|hsa:7186|TRAF2, MGC:45012, TRAP, TRAP3; TNF receptor-associated factor 2; K03173 TNF receptor-associated factor 2 (A)"	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Sphingolipid signaling pathway (ko04071);; Protein processing in endoplasmic reticulum (ko04141);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; RIG-I-like receptor signaling pathway (ko04622);; TNF signaling pathway (ko04668);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hepatitis C (ko05160);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	"MATH domain;; TRAF-type zinc finger;; Zinc finger, C3HC4 type (RING finger)"	TNF receptor-associated factor 2 GN=TRAF2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TNF receptor-associated factor 2 [Galeopterus variegatus]
ENSG00000127220(ABHD8)	--	12.18250096	403	8.260928929	281	12.73671695	335	7.51381	251	9.15648	268	9.726619034	255	0.02812498	-0.710457925	normal	0.962939609	-0.089271664	normal	0.778402103	-0.399879618	normal	0.082916713	-0.417818337	normal	--	--	--	K13701|0|ptr:748780|ABHD8; abhydrolase domain containing 8; K13701 abhydrolase domain-containing protein 8 (A)	--	[R]	General function prediction only	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Putative lysophospholipase	Abhydrolase domain-containing protein 8 GN=ABHD8 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	abhydrolase domain-containing protein 8 [Bos taurus] 
ENSG00000127241(MASP1)	--	0.023740147	2	0.058136387	5	0	0	0.02380274	2	0.029481342	0	0.011856411	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: proteolysis (GO:0006508);; 	K03992|0|nle:100601109|MASP1; mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor); K03992 mannan-binding lectin serine protease 1 [EC:3.4.21.-] (A)	Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150)	[E]	Amino acid transport and metabolism	Trypsin;; CUB domain;; Sushi domain (SCR repeat);; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain	Mannan-binding lectin serine protease 1 light chain (Precursor) GN=MASP1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mannan-binding lectin serine protease 1 isoform X1 [Orycteropus afer afer]
ENSG00000127249(ATP13A4)	--	0.052688215	2	0.012962304	1	0.02589437	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; 	K14951|0|hsa:84239|ATP13A4; ATPase type 13A4 (EC:3.6.3.-); K14951 cation-transporting ATPase 13A3/4/5 [EC:3.6.3.-] (A)	--	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; P5-type ATPase cation transporter;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Cation transporter/ATPase, N-terminus;; Putative hydrolase of sodium-potassium ATPase alpha subunit"	Probable cation-transporting ATPase 13A4 GN=ATP13A4 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: probable cation-transporting ATPase 13A4 [Odobenus rosmarus divergens]
ENSG00000127252(HRASLS)	--	0.67843	11	0.237957	4	0.876785	14	0.362864	6	0.35813	5	0.060614	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lecithin retinol acyltransferase	Phospholipid-metabolizing enzyme A-C1 GN=HRASLS OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: phospholipid-metabolizing enzyme A-C1 isoform X2 [Tupaia chinensis]
ENSG00000127311(HELB)	--	1.05271	220	1.269458	264	1.438002	294	0.820209002	172	0.786743	163	1.188327	248	0.84806988	-0.382894176	normal	0.080967507	-0.711850336	normal	0.928324737	-0.252352353	normal	0.159675972	-0.436061385	normal	[L]	"Replication, recombination and repair"	--	"K15254|0|hsa:92797|HELB, hDHB; helicase (DNA) B (EC:3.6.4.12); K15254 DNA helicase B [EC:3.6.4.12] (A)"	--	--	--	AAA domain;; Viral (Superfamily 1) RNA helicase;; UvrD-like helicase C-terminal domain;; Part of AAA domain	DNA helicase B GN=HELB OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA helicase B [Odobenus rosmarus divergens]
ENSG00000127314(RAP1B)	--	74.8669479	1642	79.44521556	1708	76.1709966	1599	117.9586261	2458	102.1650878	2118	102.3865142	2129	0.159690805	0.550774753	normal	0.934786357	0.2887381	normal	0.741473898	0.404382037	normal	0.005570095	0.416335931	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07836|1.18633e-121|tup:102472381|RAP1B; RAP1B, member of RAS oncogene family; K07836 Ras-related protein Rap-1B (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Pancreatic secretion (ko04972);; Renal cell carcinoma (ko05211)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	Ras-related protein Rap-1b (Precursor) GN=RAP1B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"Ras-related protein Rap-1b, partial [Bos mutus]"
ENSG00000127324(TSPAN8)	--	0.411387512	6	1.878338201	26	0.97026577	13	1.884124211	28	2.12767847	31	2.235146	34	0.150148263	1.943650821	normal	0.982032851	0.22056961	normal	0.574138069	1.283360457	normal	0.110063292	1.026074787	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17349|1.12999e-156|hsa:7103|TSPAN8, CO-029, TM4SF3; tetraspanin 8; K17349 tetraspanin-8 (A)"	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-8 GN=TSPAN8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetraspanin-8 [Ceratotherium simum simum]
ENSG00000127325(BEST3)	--	0.188510773	9	0.252909	7	0.373022478	8	0.810911099	28	0.762260325	25	1.433870249	34	0.595698793	1.459324087	normal	0.532900605	1.620131001	normal	0.054356725	1.892998285	normal	0.00331189	1.837378007	up	--	--	--	K13880|0|pps:100973585|BEST3; bestrophin 3; K13880 bestrophin-3 (A)	--	[R]	General function prediction only	"Bestrophin, RFP-TM, chloride channel"	Bestrophin-3 GN=BEST3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: bestrophin-3 [Galeopterus variegatus]
ENSG00000127328(RAB3IP)	--	7.764091253	477	11.7404254	434	7.259829977	433	8.19234208	582	7.520747834	514	9.317413738	568	0.924388907	0.255451763	normal	0.939219038	0.221935461	normal	0.772683031	0.382063988	normal	0.185816195	0.28673613	normal	--	--	--	K16779|0|pps:100973931|RAB3IP; RAB3A interacting protein; K16779 Rab-3A-interacting protein (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	GDP/GTP exchange factor Sec2p	Rab-3A-interacting protein OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab-3A-interacting protein-like isoform 1 [Tursiops truncatus]
ENSG00000127329(PTPRB)	--	0.879072443	100	0.560599592	91	0.6218633	80	2.388215132	330	1.932355568	264	2.502763244	315	4.38E-12	1.676641941	up	1.08E-08	1.499871295	up	2.66E-15	1.948977318	up	5.38E-13	1.724269365	up	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K05694|0|hsa:5787|PTPRB, HPTP-BETA, HPTPB, PTPB, R-PTP-BETA, VEPTP; protein tyrosine phosphatase, receptor type, B (EC:3.1.3.48); K05694 receptor-type tyrosine-protein phosphatase beta [EC:3.1.3.48] (A)"	Adherens junction (ko04520)	[T]	Signal transduction mechanisms	Fibronectin type III domain;; Protein-tyrosine phosphatase;; Ricin-type beta-trefoil lectin domain	Receptor-type tyrosine-protein phosphatase beta (Precursor) GN=PTPRB OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: receptor-type tyrosine-protein phosphatase beta [Oryctolagus cuniculus]
ENSG00000127334(DYRK2)	--	6.53527281	720	5.620224	656	6.033314	612	8.738668	948	10.34703092	1022	7.932605	852	0.801503371	0.365376598	normal	0.05785809	0.617052571	normal	0.479691242	0.468045806	normal	0.003097685	0.483783393	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K18669|0|pon:100443679|DYRK2; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2; K18669 dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Dual specificity tyrosine-phosphorylation-regulated kinase 2 GN=DYRK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 2 isoform X1 [Canis lupus familiaris]
ENSG00000127337(YEATS4)	--	19.11602104	422	19.34730813	435	18.0143639	400	23.89458773	535	26.16658956	589	24.0498646	538	0.881416356	0.310457835	normal	0.699340455	0.414582806	normal	0.689049964	0.417947471	normal	0.060387396	0.381686639	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K11341|5.19692e-147|ptr:452069|YEATS4; YEATS domain containing 4; K11341 YEATS domain-containing protein 4 (A)	--	[K]	Transcription	YEATS family	YEATS domain-containing protein 4 GN=YEATS4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: YEATS domain-containing protein 4 isoform X1 [Monodelphis domestica]
ENSG00000127362(TAS2R3)	--	0.2636643	7	0.449569	13	0.757701	18	0.447866369	13	0.237479	6	0.379425	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:50831|TAS2R3, T2R3; taste receptor, type 2, member 3; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 3 GN=TAS2R3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 3-like [Ceratotherium simum simum]
ENSG00000127364(TAS2R4)	--	0.5703323	153	0.873736	239	0.556117	102	0.673652	160	0.580789	157	0.988362812	269	0.967351928	0.033380199	normal	0.279456458	-0.622772904	normal	1.18E-07	1.377684387	up	0.802894876	0.225631979	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:50832|TAS2R4, T2R4; taste receptor, type 2, member 4; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 4 GN=TAS2R4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 4 [Galeopterus variegatus]
ENSG00000127366(TAS2R5)	--	0.224921211	3	1.156895	30	0.392488277	5	0.337842751	4	0.940795	34	0.67469	19	--	--	--	0.981851576	0.1519476	normal	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:54429|TAS2R5, T2R5; taste receptor, type 2, member 5; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 5 GN=TAS2R5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	taste receptor type 2 member 5 [Canis lupus familiaris] 
ENSG00000127377(CRYGN)	--	0.272248909	2	0.547306546	5	0	0	0	0	0.101666	0	0.102599	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Beta/Gamma crystallin	Gamma-crystallin N GN=CRYGN OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	Gamma-crystallin N [Tupaia chinensis]
ENSG00000127399(LRRC61)	--	0	0	0	0	0	0	0.070726811	2	0.203935527	5	0.0419791	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 61 GN=LRRC61 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 61 [Galeopterus variegatus]
ENSG00000127415(IDUA)	--	8.172662	328	6.832211	349	9.342263	390	7.461421	328	8.48278923	367	10.1296622	522	0.967877276	-0.030688512	normal	0.966849597	0.050911332	normal	0.710387586	0.410902359	normal	0.707950128	0.170220587	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K01217|0|hsa:3425|IDUA, IDA, MPS1; iduronidase, alpha-L- (EC:3.2.1.76); K01217 L-iduronidase [EC:3.2.1.76] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	--	--	Glycosyl hydrolases family 39	Alpha-L-iduronidase (Precursor) GN=IDUA OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: alpha-L-iduronidase [Galeopterus variegatus]
ENSG00000127418(FGFRL1)	--	11.8408152	958	8.436081249	663	10.37703214	860	12.9891455	989	13.63521103	1072	9.108454788	722	0.979150485	0.015088785	normal	0.018274971	0.670583835	normal	0.927680346	-0.260129354	normal	0.7321856	0.143953115	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Natural killer cell receptor 2B4;; Alphaherpesvirus glycoprotein E	Fibroblast growth factor receptor-like 1 (Precursor) GN=FGFRL1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor receptor-like 1 [Orcinus orca]
ENSG00000127419(TMEM175)	--	8.039117388	202	6.246883614	175	5.95259388	161	5.523953454	149	6.232430288	165	7.385949181	204	0.743835266	-0.465732806	normal	0.962090206	-0.105377448	normal	0.899254254	0.330453492	normal	0.881323279	-0.075141621	normal	[S]	Function unknown	Molecular Function: potassium channel activity (GO:0005267);; 	--	--	--	--	Protein of unknown function (DUF1211)	Transmembrane protein 175 GN=TMEM175 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 175 isoform X1 [Galeopterus variegatus]
ENSG00000127423(AUNIP)	--	3.48602	121	3.12269	107	3.52431	121	3.41783	119	2.82511	94	2.571079	90	0.968624451	-0.054183941	normal	0.958177515	-0.205207793	normal	0.881415855	-0.429060833	normal	0.646851954	-0.225890232	normal	--	--	--	"K16800|0|hsa:79000|AUNIP, AIBP, C1orf135; aurora kinase A and ninein interacting protein; K16800 aurora kinase A and ninein-interacting protein (A)"	--	--	--	Aurora kinase A and ninein interacting protein	Aurora kinase A and ninein-interacting protein GN=AUNIP OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: aurora kinase A and ninein-interacting protein [Galeopterus variegatus]
ENSG00000127445(PIN1)	--	49.468926	841	48.21981	859	55.808575	1007	45.432064	794	41.323467	705	40.935129	712	0.971494256	-0.113585443	normal	0.891858913	-0.305865939	normal	0.310972676	-0.50749492	normal	0.082171142	-0.313245631	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Molecular Function: isomerase activity (GO:0016853);; 	"K09578|7.3236e-108|ptr:745021|PIN1; peptidylprolyl cis/trans isomerase, NIMA-interacting 1; K09578 peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8] (A)"	RIG-I-like receptor signaling pathway (ko04622)	[O]	"Posttranslational modification, protein turnover, chaperones"	PPIC-type PPIASE domain;; PPIC-type PPIASE domain;; WW domain	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 GN=PIN1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [Orcinus orca] 
ENSG00000127452(FBXL12)	--	7.960113175	234	8.543714101	252	7.95277161	242	9.304956003	228	10.08296002	249	12.28734872	274	0.965169669	-0.067855579	normal	0.965499138	-0.038472284	normal	0.95334507	0.16987915	normal	0.967009454	0.02422433	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10278|0|ptr:455688|FBXL12; F-box and leucine-rich repeat protein 12; K10278 F-box and leucine-rich repeat protein 12 (A)	--	[R]	General function prediction only	F-box-like;; F-box domain	F-box/LRR-repeat protein 12 GN=FBXL12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 12 isoform X1 [Sus scrofa]
ENSG00000127463(EMC1)	--	21.70243417	2089	18.97028678	1923	19.73999589	1960	19.89181618	2003	19.67110867	1903	18.14778095	1806	0.984786388	-0.091413663	normal	0.985759111	-0.036480919	normal	0.98136217	-0.126245695	normal	0.713277133	-0.085743178	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1620);; PQQ-like domain;; PQQ enzyme repeat	ER membrane protein complex subunit 1 (Precursor) GN=EMC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ER membrane protein complex subunit 1 isoformX1 [Equus caballus]
ENSG00000127481(UBR4)	--	25.62721062	6307	27.85631363	6760	29.23704009	6961	37.85183833	5940	32.7828061	5404	40.80874742	6270	0.992569087	-0.117293815	normal	0.938688546	-0.344335771	normal	0.991055449	-0.15908414	normal	0.282178455	-0.206267688	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K10691|0|hsa:23352|UBR4, RBAF600, ZUBR1, p600; ubiquitin protein ligase E3 component n-recognin 4; K10691 E3 ubiquitin-protein ligase UBR4 [EC:6.3.2.19] (A)"	Viral carcinogenesis (ko05203)	[T]	Signal transduction mechanisms	E3 ubiquitin-protein ligase UBR4;; Putative zinc finger in N-recognin (UBR box)	E3 ubiquitin-protein ligase UBR4 GN=UBR4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase UBR4 [Ceratotherium simum simum]
ENSG00000127483(HP1BP3)	--	63.32850815	4465	70.92040729	4814	71.9999046	4539	43.98154276	3024	49.180568	3309	57.656198	4075	0.080816647	-0.592784697	normal	0.183542161	-0.562053098	normal	0.987130671	-0.16380824	normal	0.004760087	-0.429204604	normal	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	--	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	Heterochromatin protein 1-binding protein 3 GN=HP1BP3 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: heterochromatin protein 1-binding protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000127507(ADGRE2)	--	1.161455128	126	0.699320153	78	1.021344117	112	0.672134846	81	1.018733261	110	0.578285494	59	0.521517918	-0.658165743	normal	0.866999023	0.466875439	normal	0.104050696	-0.915681041	normal	0.495777226	-0.359483339	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08443|0|ggo:101140763|EMR2; LOW QUALITY PROTEIN: EGF-like module-containing mucin-like hormone receptor-like 2; K08443 egf-like module containing, mucin-like, hormone receptor-like 2 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; EGF domain;; Latrophilin/CL-1-like GPS domain;; MSP1 EGF domain 1;; EGF-like domain	EGF-like module-containing mucin-like hormone receptor-like 2 (Precursor) GN=EMR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: EGF-like module-containing mucin-like hormone receptor-like 2 [Ursus maritimus]
ENSG00000127511(SIN3B)	--	8.921824197	907	8.485520818	877	10.29243507	1008	10.08590913	996	9.230015155	972	10.15644241	1014	0.974487195	0.104042709	normal	0.971188636	0.126745249	normal	0.97974319	0.000270167	normal	0.776248753	0.074065399	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[B]	Chromatin structure and dynamics	Paired amphipathic helix repeat;; Sin3 family co-repressor	Paired amphipathic helix protein Sin3b OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: paired amphipathic helix protein Sin3b [Odobenus rosmarus divergens]
ENSG00000127526(SLC35E1)	--	12.7023214	1091	14.1888211	1230	11.91906262	1080	13.26483548	1201	12.34505415	1099	12.67365318	1157	0.976627208	0.10760832	normal	0.965168411	-0.183654449	normal	0.977772466	0.090943056	normal	0.998125709	0.002072994	normal	--	--	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15283|0|ptr:455813|SLC35E1; solute carrier family 35, member E1; K15283 solute carrier family 35, member E1 (A)"	--	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Triose-phosphate Transporter family;; EamA-like transporter family;; UAA transporter family	Solute carrier family 35 member E1 GN=SLC35E1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 35 member E1 [Sus scrofa]
ENSG00000127527(EPS15L1)	--	8.114928403	484	7.131028038	460	7.572906977	491	8.128070614	530	7.646203726	462	9.071212473	555	0.967152556	0.099850095	normal	0.970124648	-0.015117975	normal	0.957012143	0.167986377	normal	0.774759408	0.087389948	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Cytoskeletal-regulatory complex EF hand;; EF hand;; EF-hand domain pair;; EF-hand domain	Epidermal growth factor receptor substrate 15-like 1 GN=EPS15L1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor receptor pathway substrate 15-like 1 isoform X1 [Sus scrofa]
ENSG00000127528(KLF2)	--	7.61068201	190	4.681553937	118	6.77876756	176	3.284703322	83	1.1886802	30	1.49339091	38	7.01E-05	-1.210401689	down	6.00E-08	-1.943949431	down	8.39E-13	-2.175643044	down	0.000155181	-1.704341863	down	[R]	General function prediction only	--	"K17845|8.44207e-139|hsa:10365|KLF2, LKLF; Kruppel-like factor 2; K17845 krueppel-like factor 2 (A)"	FoxO signaling pathway (ko04068)	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain"	Krueppel-like factor 2 GN=KLF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: Krueppel-like factor 2 [Lipotes vexillifer]
ENSG00000127554(GFER)	--	39.9609507	1524	33.66045211	1395	34.18047736	1509	31.41169551	1560	42.39028429	1692	33.36949575	1475	0.984328857	0.002848025	normal	0.946597476	0.256784797	normal	0.983501766	-0.041127603	normal	0.76317874	0.07305372	normal	--	--	Molecular Function: thiol oxidase activity (GO:0016972);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K17783|1.00006e-124|hsa:2671|GFER, ALR, ERV1, HERV1, HPO, HPO1, HPO2, HSS; growth factor, augmenter of liver regeneration (EC:1.8.3.2); K17783 mitochondrial FAD-linked sulfhydryl oxidase [EC:1.8.3.2] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Erv1 / Alr family	FAD-linked sulfhydryl oxidase ALR GN=GFER OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: FAD-linked sulfhydryl oxidase ALR isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000127561(SYNGR3)	--	15.041074	484	13.57898897	439	12.68331428	413	9.307845467	295	10.13577396	326	10.19006592	339	0.010121824	-0.742073706	normal	0.630219022	-0.448973537	normal	0.900611722	-0.291965914	normal	0.017530774	-0.497737881	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Membrane-associating domain	Synaptogyrin-3 GN=SYNGR3 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptogyrin-3 [Canis lupus familiaris]
ENSG00000127564(PKMYT1)	--	36.37151017	1003	36.00274382	999	44.27803776	1210	36.56523778	982	39.63171629	957	31.35001838	921	0.978032795	-0.06126409	normal	0.976110737	-0.083263516	normal	0.717835811	-0.401448475	normal	0.342423194	-0.188483799	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K06633|0|pps:100991081|PKMYT1; protein kinase, membrane associated tyrosine/threonine 1; K06633 membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [EC:2.7.11.1] (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase GN=PKMYT1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase [Pteropus alecto] 
ENSG00000127578(WFIKKN1)	--	0.123225	4	0.328985	11	0.315882	10	0.121782	4	0.118873	3	0.210633	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Molecular Function: peptidase inhibitor activity (GO:0030414);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Kunitz/Bovine pancreatic trypsin inhibitor domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; WAP-type (Whey Acidic Protein) 'four-disulfide core';; Kazal-type serine protease inhibitor domain;; Immunoglobulin domain;; Immunoglobulin domain;; UNC-6/NTR/C345C module	"WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 (Precursor) GN=WFIKKN1 OS=Homo sapiens (Human) PE=1 SV=1"	W	Extracellular structures	"PREDICTED: WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1 [Pteropus alecto] "
ENSG00000127580(WDR24)	--	5.099135607	329	4.563497073	297	4.753814894	314	4.836349385	311	4.738006221	305	6.571576718	426	0.962357144	-0.111469731	normal	0.966755947	0.016835165	normal	0.682518462	0.430012787	normal	0.709200685	0.128385577	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 24 GN=WDR24 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"WD repeat-containing protein 24, partial [Bos mutus]"
ENSG00000127585(FBXL16)	--	3.648751808	220	2.9618615	172	4.55081991	257	2.23683657	119	1.805656907	92	2.2199743	110	0.006254408	-0.9086033	normal	0.018779639	-0.912969901	normal	5.98E-06	-1.221241127	down	0.000129105	-1.036640163	down	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10282|0|hsa:146330|FBXL16, C16orf22, Fbl16, c380A1.1; F-box and leucine-rich repeat protein 16; K10282 F-box and leucine-rich repeat protein 16 (A)"	--	[R]	General function prediction only	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat	F-box/LRR-repeat protein 16 GN=FBXL16 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 16 [Odobenus rosmarus divergens] 
ENSG00000127586(CHTF18)	--	6.8841256	426	6.233377	393	6.8999505	442	5.3058817	320	5.786718704	355	7.57683896	472	0.646279457	-0.441768297	normal	0.953418691	-0.16745848	normal	0.967526454	0.086163723	normal	0.612920904	-0.156571682	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	"K11269|0|hsa:63922|CHTF18, C16orf41, C321D2.2, C321D2.3, C321D2.4, CHL12, Ctf18, RUVBL; CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae); K11269 chromosome transmission fidelity protein 18 (A)"	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily);; Rad17 cell cycle checkpoint protein;; AAA domain;; Holliday junction DNA helicase ruvB N-terminus	Chromosome transmission fidelity protein 18 homolog GN=CHTF18 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: chromosome transmission fidelity protein 18 homolog [Physeter catodon]
ENSG00000127588(GNG13)	--	0	0	0.19768	3	0	0	0.0641294	1	0	0	0.248721	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04547|1.94699e-41|mcc:722398|GNG13; guanine nucleotide binding protein (G protein), gamma 13; K04547 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Taste transduction (ko04742);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 (Precursor) GN=GNG13 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13 [Loxodonta africana]
ENSG00000127603(MACF1)	--	27.2996066	7588	31.92548773	9171	31.24034474	9060	30.06576529	8149	28.04730218	7074	33.99844755	9582	0.994929221	0.072057008	normal	0.897109942	-0.395904827	normal	0.99554923	0.07251255	normal	0.79709455	-0.078462173	normal	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoskeleton (GO:0005856);; Molecular Function: microtubule binding (GO:0008017);; 	--	--	[Z]	Cytoskeleton	Spectrin repeat;; Plectin repeat;; Calponin homology (CH) domain;; Growth-Arrest-Specific Protein 2 Domain;; EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand;; CAMSAP CH domain	"Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 GN=MACF1 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	PREDICTED: microtubule-actin cross-linking factor 1 isoform X1 [Equus przewalskii]
ENSG00000127616(SMARCA4)	--	2.607665528	355	2.278997425	314	2.581932601	362	1.743139034	240	2.447746339	337	2.5785693	356	0.214059849	-0.592476368	normal	0.964438948	0.080184662	normal	0.96851278	-0.032267962	normal	0.589063002	-0.163910068	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on acid anhydrides (GO:0016817);; Molecular Function: histone binding (GO:0042393);; "	K11647|0|ggo:101141278|SMARCA4; transcription activator BRG1 isoform 1; K11647 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4 [EC:3.6.4.-] (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	"SNF2 family N-terminal domain;; Bromodomain;; Snf2-ATP coupling, chromatin remodelling complex;; BRK domain;; HSA;; Helicase conserved C-terminal domain;; QLQ;; Type III restriction enzyme, res subunit"	Transcription activator BRG1 GN=SMARCA4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: transcription activator BRG1 isoform X3 [Felis catus]
ENSG00000127663(KDM4B)	--	5.025902271	583	5.3382611	611	5.086158909	595	7.385793801	824	5.280967634	597	6.445520633	735	0.484263848	0.467275853	normal	0.971816764	-0.054730958	normal	0.897468794	0.295885318	normal	0.229420697	0.247498492	normal	--	--	--	--	--	[L]	"Replication, recombination and repair"	--	Lysine-specific demethylase 4B GN=KDM4B OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: lysine-specific demethylase 4B [Sus scrofa]
ENSG00000127666(TICAM1)	--	4.833894511	260	4.374456962	232	5.287431327	289	3.577728009	191	3.588162638	183	3.674528558	195	0.666536926	-0.472499056	normal	0.864505462	-0.36105094	normal	0.342289136	-0.572217616	normal	0.075296859	-0.477722062	normal	--	--	--	"K05842|0|hsa:148022|TICAM1, IIAE6, MyD88-3, PRVTIRB, TICAM-1, TRIF; toll-like receptor adaptor molecule 1; K05842 toll-like receptor adapter molecule 1 (A)"	NF-kappa B signaling pathway (ko04064);; Toll-like receptor signaling pathway (ko04620);; Pertussis (ko05133);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	RIP homotypic interaction motif	TIR domain-containing adapter molecule 1 GN=TICAM1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TIR domain-containing adapter molecule 1 [Galeopterus variegatus]
ENSG00000127720(METTL25)	--	1.109834	33	2.022158	46	1.247430024	43	1.07737167	38	1.721367	56	1.467554896	47	0.981543303	0.165516058	normal	0.969331133	0.254765687	normal	0.978885557	0.116125206	normal	0.817737445	0.188444251	normal	--	--	--	--	--	[A]	RNA processing and modification	Methyltransferase domain	Methyltransferase-like protein 25 GN=METTL25 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: methyltransferase-like protein 25-like [Tupaia chinensis]
ENSG00000127743(IL17B)	--	0	0	0	0	0	0	0.0968777	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular region (GO:0005576);; 	K05490|1.43435e-110|pps:100980380|IL17B; interleukin 17B; K05490 interleukin 17B (A)	Cytokine-cytokine receptor interaction (ko04060)	--	--	Interleukin-17	Interleukin-17B (Precursor) GN=IL17B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: interleukin-17B [Tursiops truncatus]
ENSG00000127774(EMC6)	--	111.76341	784	99.2998	734	109.2976	818	110.8832	823	122.717	870	103.2183	750	0.976372838	0.039131664	normal	0.946106765	0.22338562	normal	0.968541379	-0.133244337	normal	0.886828978	0.043355212	normal	--	--	--	--	--	[S]	Function unknown	Rab5-interacting protein (Rab5ip)	ER membrane protein complex subunit 6 GN=EMC6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ER membrane protein complex subunit 6 [Ailuropoda melanoleuca] 
ENSG00000127804(METTL16)	--	14.67697	1555	16.027399	1708	15.478694	1633	13.98693829	1492	13.8980561	1469	14.5922	1550	0.981550504	-0.090408101	normal	0.955228682	-0.238672016	normal	0.982501356	-0.083468665	normal	0.498962738	-0.139258229	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	"K11393|0|hsa:79066|METTL16, METT10D; methyltransferase like 16 (EC:2.1.1.-); K11393 methyltransferase [EC:2.1.1.-] (A)"	--	[S]	Function unknown	Protein of unknown function (DUF890)	Methyltransferase-like protein 16 GN=METTL16 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: methyltransferase-like protein 16 [Ailuropoda melanoleuca]
ENSG00000127824(TUBA4A)	--	55.9875016	1915	52.7129705	1802	63.1471294	2090	153.6124616	5131	132.5513947	4549	67.50688776	2305	3.22E-15	1.390355227	up	5.02E-13	1.313805702	up	0.9826153	0.132880778	normal	0.064737098	1.022347329	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07374|0|umr:103662744|TUBA4A; tubulin, alpha 4a; K07374 tubulin alpha (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha-4A chain GN=TUBA4A OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin alpha-4A chain [Orcinus orca]
ENSG00000127831(VIL1)	--	0.0103842	1	0.2873116	7	0.148477403	3	0	0	0	0	0.0102677	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	"K05761|0|hsa:7429|VIL1, D2S1471, VIL; villin 1; K05761 villin 1 (A)"	--	[Z]	Cytoskeleton	Gelsolin repeat;; Villin headpiece domain	Villin-1 GN=VIL1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: villin-1 [Vicugna pacos]
ENSG00000127837(AAMP)	--	55.09561973	1934	50.1013947	1967	52.423605	2034	38.34672698	1462	38.22148213	1406	38.14791692	1308	0.628435385	-0.434078635	normal	0.342393101	-0.505365017	normal	0.020814773	-0.644645907	normal	0.000255545	-0.528569421	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Angio-associated migratory cell protein GN=AAMP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: angio-associated migratory cell protein isoform X3 [Mustela putorius furo] 
ENSG00000127838(PNKD)	--	57.74904	1665	55.16740003	1583	56.57728357	1535	32.81540297	867	32.89469392	946	37.95569139	1237	1.38E-06	-0.970985328	normal	0.001353532	-0.763221523	normal	0.892973684	-0.319333422	normal	1.39E-05	-0.66932049	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Metallo-beta-lactamase superfamily;; Beta-lactamase superfamily domain	Probable hydrolase PNKD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: probable hydrolase PNKD isoform X1 [Tupaia chinensis]
ENSG00000127863(TNFRSF19)	--	0.672567063	46	0.423420272	29	0.232751944	15	0.713381211	49	0.709498085	48	0.450099009	31	0.979484575	0.058424797	normal	0.897665567	0.67782791	normal	0.881512875	0.96972614	normal	0.507987627	0.484543353	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05155|0|hsa:55504|TNFRSF19, TAJ, TAJ-alpha, TRADE, TROY; tumor necrosis factor receptor superfamily, member 19; K05155 tumor necrosis factor receptor superfamily member 19 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	--	Tumor necrosis factor receptor superfamily member 19 (Precursor) GN=TNFRSF19 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 19 isoform 1 [Ceratotherium simum simum]
ENSG00000127870(RNF6)	--	14.18049072	886	16.18570242	1020	16.57985095	1029	15.800698	1004	15.64785	987	19.256358	1211	0.968634044	0.149305077	normal	0.977330894	-0.068770062	normal	0.95182682	0.226357473	normal	0.654958411	0.105074819	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Anaphase-promoting complex subunit 11 RING-H2 finger"	E3 ubiquitin-protein ligase RNF6 GN=RNF6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF6 isoform X1 [Equus caballus] 
ENSG00000127884(ECHS1)	--	75.4418	2187	71.4126	2120	82.2975	2439	86.2938	2517	84.7438	2442	77.4579	2244	0.979007162	0.17180716	normal	0.976770911	0.182451034	normal	0.983740009	-0.12842548	normal	0.758379108	0.073279794	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	"K07511|0|hsa:1892|ECHS1, SCEH; enoyl CoA hydratase, short chain, 1, mitochondrial (EC:4.2.1.17); K07511 enoyl-CoA hydratase [EC:4.2.1.17] (A)"	"Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; Carbon metabolism (ko01200);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family;; Peptidase family S49	"Enoyl-CoA hydratase, mitochondrial (Precursor) GN=ECHS1 OS=Homo sapiens (Human) PE=1 SV=4"	I	Lipid transport and metabolism	"PREDICTED: enoyl-CoA hydratase, mitochondrial isoform X2 [Mustela putorius furo]"
ENSG00000127914(AKAP9)	--	8.250490478	1854	9.951105717	2194	8.4129232	2169	10.15114468	2137	8.365289	1905	9.818889386	2423	0.976249025	0.17397903	normal	0.965562658	-0.22503246	normal	0.981286941	0.151373008	normal	0.902498766	0.035656879	normal	--	--	--	"K16551|0|hsa:10142|AKAP9, AKAP-9, AKAP350, AKAP450, CG-NAP, HYPERION, LQT11, MU-RMS-40.16A, PPP1R45, PRKA9, YOTIAO; A kinase (PRKA) anchor protein 9; K16551 A-kinase anchor protein 9 (A)"	--	--	--	Pericentrin-AKAP-450 domain of centrosomal targeting protein	A-kinase anchor protein 9 GN=AKAP9 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 9 [Galeopterus variegatus]
ENSG00000127920(GNG11)	--	29.9512	1364	28.6859	1300	31.0065	1387	22.617	1034	26.0772	1188	33.6092	1534	0.624106369	-0.429881523	normal	0.972268664	-0.151219247	normal	0.976908032	0.136897269	normal	0.676191309	-0.129001137	normal	--	--	--	"K04546|5.29667e-44|rno:64199|Gng11; guanine nucleotide binding protein (G protein), gamma 11; K04546 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 (Precursor) GN=GNG11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-11 [Ovis aries] 
ENSG00000127922(SEM1)-3	--	138.893602	834	127.3580527	1061	146.9406029	971	166.5941326	1063	163.732043	901	144.438829	939	0.879988873	0.318669	normal	0.93471733	-0.256854404	normal	0.9778598	-0.056548015	normal	0.997845419	-0.003127502	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000127946(HIP1)	--	24.52430419	4479	19.93194883	3641	23.21941941	4236	17.53236499	3178	17.18014151	3122	11.48379355	2103	0.292062519	-0.525674551	normal	0.970754137	-0.243181557	normal	1.01E-07	-1.018018602	down	0.007405051	-0.578388311	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: phospholipid binding (GO:0005543);; 	K04559|0|ptr:463479|HIP1; huntingtin interacting protein 1; K04559 huntingtin interacting protein 1 (A)	Huntington's disease (ko05016)	[Z]	Cytoskeleton	ANTH domain;; I/LWEQ domain;; ENTH domain	Huntingtin-interacting protein 1 GN=HIP1 OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: huntingtin-interacting protein 1 isoform X1 [Equus caballus]
ENSG00000127947(PTPN12)	--	37.01990279	2282	36.31431996	2225	34.87391902	2107	34.57982644	2141	37.58717262	2265	36.73416728	2283	0.983549047	-0.122760905	normal	0.98757823	0.004276276	normal	0.984579139	0.107375049	normal	0.989067348	-0.004824146	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	K18024|0|ggo:101147493|PTPN12; tyrosine-protein phosphatase non-receptor type 12 isoform 1; K18024 tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] (A)	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase	Tyrosine-protein phosphatase non-receptor type 12 GN=PTPN12 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 12 [Oryctolagus cuniculus]
ENSG00000127948(POR)	--	73.96273495	3831	92.83851513	4420	82.0394308	4101	42.14915492	2129	49.32643604	2483	70.74803689	3572	1.84E-05	-0.877897736	normal	6.66E-05	-0.852993593	normal	0.9804946	-0.207453065	normal	0.013840965	-0.61354348	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00327|0|hsa:5447|POR, CPR, CYPOR, P450R; P450 (cytochrome) oxidoreductase (EC:1.6.2.4); K00327 NADPH-ferrihemoprotein reductase [EC:1.6.2.4] (A)"	--	[C]	Energy production and conversion	FAD binding domain;; Flavodoxin;; Oxidoreductase NAD-binding domain	NADPH--cytochrome P450 reductase GN=POR OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: NADPH--cytochrome P450 reductase isoform X1 [Myotis davidii]
ENSG00000127951(FGL2)	--	0.19939	13	0.1334968	3	0.0306439	1	0.0753218	5	0.133087	8	0.0909596	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Fibroleukin (Precursor) GN=FGL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: fibroleukin [Equus caballus] 
ENSG00000127952(STYXL1)	--	18.37134693	362	19.193834	382	17.47385325	341	18.2029652	370	17.16726534	352	18.25481649	374	0.969008571	0.00070037	normal	0.958559921	-0.138850923	normal	0.961451358	0.124447929	normal	0.991325506	-0.006790597	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18047|0|hsa:51657|STYXL1, DUSP24, MK-STYX; serine/threonine/tyrosine interacting-like 1; K18047 serine/threonine/tyrosine-interacting-like protein 1 (A)"	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain"	Serine/threonine/tyrosine-interacting-like protein 1 GN=STYXL1 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: serine/threonine/tyrosine-interacting-like protein 1 [Vicugna pacos]
ENSG00000127954(STEAP4)	--	0.084229332	3	0.006341447	1	0.006335216	0	0.026839095	2	0.052215717	1	0.028900744	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	--	--	Ferric reductase like transmembrane component;; NADP oxidoreductase coenzyme F420-dependent	Metalloreductase STEAP4 GN=STEAP4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: metalloreductase STEAP4 isoform X1 [Equus przewalskii] 
ENSG00000127955(GNAI1)	--	41.13916226	2041	53.86844279	2458	44.53952967	2133	29.05888241	1310	32.09628663	1376	42.6292324	1987	0.010912779	-0.669906517	normal	6.44E-05	-0.857715283	normal	0.983680065	-0.110502343	normal	0.03635314	-0.525173029	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04630|0|ptr:472425|GNAI1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; K04630 guanine nucleotide-binding protein G(i) subunit alpha (A)"	Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Axon guidance (ko04360);; Tight junction (ko04530);; Gap junction (ko04540);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pertussis (ko05133);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Guanine nucleotide-binding protein G(i) subunit alpha-1 GN=GNAI1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(i) subunit alpha-1 isoform X1 [Bison bison bison]
ENSG00000127980(PEX1)	--	7.50262634	605	7.001784481	563	8.039453512	624	7.027860712	563	7.73594128	617	7.060759188	562	0.964411348	-0.134278865	normal	0.967110244	0.110425608	normal	0.960427192	-0.158861449	normal	0.840331581	-0.061834528	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Cellular Component: peroxisome (GO:0005777);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Biological Process: peroxisome organization (GO:0007031);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	"K13338|0|hsa:5189|PEX1, PBD1A, PBD1B, ZWS, ZWS1; peroxisomal biogenesis factor 1; K13338 peroxin-1 (A)"	Peroxisome (ko04146)	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATPase family associated with various cellular activities (AAA);; Peroxisome biogenesis factor 1, N-terminal;; Peroxisome biogenesis factor 1, N-terminal;; Part of AAA domain;; AAA ATPase domain;; AAA domain;; AAA domain;; IstB-like ATP binding protein;; AAA domain;; ABC transporter;; Sigma-54 interaction domain;; AAA domain (Cdc48 subfamily);; AAA domain;; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (dynein-related subfamily);; RNA helicase;; Type II/IV secretion system protein;; Sigma-54 interaction domain;; Zeta toxin;; Magnesium chelatase, subunit ChlI;; Protein of unknown function (DUF815)"	Peroxisome biogenesis factor 1 GN=PEX1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxisome biogenesis factor 1 [Ceratotherium simum simum]
ENSG00000127989(MTERF1)	--	9.15562009	281	9.001873059	262	8.968352088	258	10.05119848	298	7.880322397	260	10.25047634	301	0.966407906	0.053625206	normal	0.965805961	-0.032294624	normal	0.942495259	0.212944334	normal	0.839661687	0.079559127	normal	--	--	"Molecular Function: double-stranded DNA binding (GO:0003690);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15031|0|pps:100987055|MTERF1, MTERF; mitochondrial transcription termination factor 1; K15031 transcription termination factor, mitochondrial (A)"	--	[KR]	Transcription;; General function prediction only	mTERF	"Transcription termination factor 1, mitochondrial (Precursor) GN=MTERF1 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: transcription termination factor, mitochondrial [Ceratotherium simum simum]"
ENSG00000127990(SGCE)	--	33.70614706	996	33.79229501	1001	31.417464	934	28.06020678	867	34.22843715	1001	35.14133801	1093	0.946017655	-0.230564405	normal	0.978930732	-0.021394236	normal	0.952796767	0.218180631	normal	0.986272296	-0.005902204	normal	--	--	Cellular Component: sarcoglycan complex (GO:0016012);; 	--	--	[S]	Function unknown	Sarcoglycan alpha/epsilon	Epsilon-sarcoglycan GN=SGCE OS=Homo sapiens (Human) PE=1 SV=6	S	Function unknown	PREDICTED: epsilon-sarcoglycan isoform X1 [Vicugna pacos]
ENSG00000127993(RBM48)	--	3.98664563	130	4.022397936	142	4.354584468	153	4.040222631	149	3.470524676	126	3.692460913	137	0.959430474	0.164155324	normal	0.954589483	-0.191724597	normal	0.958575386	-0.16591321	normal	0.908108189	-0.066134718	normal	--	--	--	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 48 GN=RBM48 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: RNA-binding protein 48 [Equus caballus] 
ENSG00000127995(CASD1)	--	13.00814	666	16.53129	871	13.90006	702	10.60366	553	11.73468018	597	14.74531	755	0.89365711	-0.298318379	normal	0.155410343	-0.565175501	normal	0.971836343	0.09651365	normal	0.389564893	-0.253538171	normal	--	--	--	--	--	[R]	General function prediction only	10 TM Acyl Transferase domain found in Cas1p;; GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p	CAS1 domain-containing protein 1 (Precursor) GN=CASD1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: CAS1 domain-containing protein 1 [Camelus bactrianus] 
ENSG00000128000(ZNF780B)	--	7.43933671	807	7.913250637	827	9.61982	815	6.131716602	733	8.176053201	876	6.569736326	898	0.961716934	-0.169249448	normal	0.975650246	0.061507693	normal	0.970027233	0.131391598	normal	0.974200785	0.013214322	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:163131|ZNF780B, ZNF779; zinc finger protein 780B; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; CHY zinc finger;; Probable zinc-binding domain"	Zinc finger protein 780B GN=ZNF780B OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 780A-like [Ursus maritimus]
ENSG00000128011(LRFN1)	--	18.660044	1105	12.18626669	744	14.33448	862	11.14214	652	12.2875421	729	4.95579628	298	0.000691315	-0.790485957	normal	0.97437349	-0.050706239	normal	6.55E-15	-1.535864762	down	0.123099924	-0.714155193	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16354|0|hsa:57622|LRFN1, SALM2; leucine rich repeat and fibronectin type III domain containing 1; K16354 leucine-rich repeat and fibronectin type-III domain-containing protein 1 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Immunoglobulin I-set domain;; Immunoglobulin domain;; Leucine Rich Repeat;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Leucine Rich repeat	Leucine-rich repeat and fibronectin type III domain-containing protein 1 (Precursor) GN=LRFN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and fibronectin type III domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000128016(ZFP36)	--	13.78222276	377	15.5012268	400	14.95241186	391	16.69945644	442	16.68041187	454	21.59715451	568	0.946934111	0.197904138	normal	0.955783481	0.160695191	normal	0.301202373	0.528724689	normal	0.175753733	0.305426528	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	"K15308|1.00964e-129|hsa:7538|ZFP36, G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36; ZFP36 ring finger protein; K15308 tristetraprolin (A)"	HTLV-I infection (ko05166)	[R]	General function prediction only	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Tristetraprolin GN=ZFP36 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	tristetraprolin [Sus scrofa] 
ENSG00000128039(SRD5A3)	--	7.41523025	214	7.701125	249	5.30574	209	9.1463225	224	5.703098	208	11.843344	290	0.966510912	0.034811384	normal	0.917899435	-0.279131065	normal	0.67182092	0.461412095	normal	0.846270808	0.082876918	normal	--	--	"Cellular Component: cytoplasm (GO:0005737);; Biological Process: lipid metabolic process (GO:0006629);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; "	K12345|0|ptr:471241|SRD5A3; steroid 5 alpha-reductase 3; K12345 3-oxo-5-alpha-steroid 4-dehydrogenase 3 [EC:1.3.1.22 1.3.1.94] (A)	Steroid hormone biosynthesis (ko00140)	[I]	Lipid transport and metabolism	3-oxo-5-alpha-steroid 4-dehydrogenase	Polyprenol reductase GN=SRD5A3 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: polyprenol reductase [Lipotes vexillifer]
ENSG00000128045(RASL11B)	--	0.0632709	2	0	0	0.0927709	2	0.0313384	1	0.0613374	1	0.0313909	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07853|9.2111e-174|pps:100981119|RASL11B; RAS-like, family 11, member B; K07853 Ras-like protein family member 11B (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B	Ras-like protein family member 11B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ras-like protein family member 11B [Ceratotherium simum simum]
ENSG00000128050(PAICS)	--	91.8813639	4915	90.1376209	4670	102.580798	5181	95.875602	5108	86.3710635	4642	66.9527434	3650	0.993364509	0.024727263	normal	0.99267977	-0.030092811	normal	0.36824099	-0.513446062	normal	0.458266581	-0.162047319	normal	[F]	Nucleotide transport and metabolism	Biological Process: 'de novo' IMP biosynthetic process (GO:0006189);; 	"K01587|0|hsa:10606|PAICS, ADE2, ADE2H1, AIRC, PAIS; phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase (EC:6.3.2.6 4.1.1.21); K01587 phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6] (A)"	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	SAICAR synthetase;; AIR carboxylase	Phosphoribosylaminoimidazole carboxylase GN=PAICS OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: multifunctional protein ADE2 isoform 1 [Orcinus orca]
ENSG00000128052(KDR)	--	0.0411943	5	0.0409582	5	0.00815343	0	0.065982	8	0.0240692	2	0.0246438	3	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05098|0|hsa:3791|KDR, CD309, FLK1, VEGFR, VEGFR2; kinase insert domain receptor (EC:2.7.10.1); K05098 kinase insert domain protein receptor [EC:2.7.10.1] (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Immunoglobulin I-set domain;; Protein kinase domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Vascular endothelial growth factor receptor 2 (Precursor) GN=KDR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: vascular endothelial growth factor receptor 2 [Balaenoptera acutorostrata scammoni]
ENSG00000128059(PPAT)	--	13.922195	794	13.587519	775	15.93666	889	14.64802	839	13.305921	755	10.77777	612	0.976222034	0.048608036	normal	0.974451935	-0.059029516	normal	0.190367758	-0.545817461	normal	0.411635148	-0.177927137	normal	[F]	Nucleotide transport and metabolism	Biological Process: nucleoside metabolic process (GO:0009116);; 	"K00764|0|hsa:5471|PPAT, ATASE, GPAT, PRAT; phosphoribosyl pyrophosphate amidotransferase (EC:2.4.2.14); K00764 amidophosphoribosyltransferase [EC:2.4.2.14] (A)"	"Purine metabolism (ko00230);; Alanine, aspartate and glutamate metabolism (ko00250)"	[F]	Nucleotide transport and metabolism	Glutamine amidotransferases class-II;; Glutamine amidotransferase domain;; Glutamine amidotransferase domain;; Phosphoribosyl transferase domain;; Glutamine amidotransferases class-II	Amidophosphoribosyltransferase (Precursor) GN=PPAT OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: amidophosphoribosyltransferase isoform X1 [Galeopterus variegatus]
ENSG00000128165(ADM2)	--	1.249983	117	1.212412138	109	0.669918614	64	0.334225545	24	0.219364079	20	0.796159647	75	5.84E-10	-2.244404754	down	3.84E-10	-2.381500825	down	0.966710463	0.215812128	normal	0.062190678	-1.303611384	normal	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Calcitonin / CGRP / IAPP family	Intermedin-short (Precursor) GN=ADM2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: ADM2 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000128185(DGCR6L)	--	18.10183	381	17.808528	387	17.432211	384	18.62680071	406	18.382821	385	19.937196	425	0.967897729	0.060619644	normal	0.968237672	-0.028788889	normal	0.960383805	0.137549981	normal	0.877704068	0.056920437	normal	--	--	--	--	--	[S]	Function unknown	DiGeorge syndrome critical region 6 (DGCR6) protein	Protein DGCR6L GN=DGCR6L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein DGCR6-like [Galeopterus variegatus]
ENSG00000128191(DGCR8)	--	6.940009202	652	10.07702006	918	8.561402521	724	8.881220265	839	8.988072617	841	7.339531	666	0.856595363	0.332274825	normal	0.967490306	-0.147560835	normal	0.967588623	-0.128479062	normal	0.985016047	0.010317519	normal	--	--	--	K18419|0|pps:100985198|DGCR8; DGCR8 microprocessor complex subunit; K18419 microprocessor complex subunit DGCR8 (A)	--	[R]	General function prediction only	Double-stranded RNA binding motif	Microprocessor complex subunit DGCR8 GN=DGCR8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: microprocessor complex subunit DGCR8 [Felis catus]
ENSG00000128203(ASPHD2)	--	1.52832	87	1.05299	61	1.12373	65	1.80742	104	1.27628	73	1.05869	61	0.958953066	0.223057549	normal	0.964563025	0.232388598	normal	0.974652748	-0.097577981	normal	0.836981988	0.137056823	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: peptidyl-amino acid modification (GO:0018193);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Aspartyl/Asparaginyl beta-hydroxylase	Aspartate beta-hydroxylase domain-containing protein 2 GN=ASPHD2 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: aspartate beta-hydroxylase domain-containing protein 2 [Ursus maritimus]
ENSG00000128218(VPREB3)	--	1.45960644	5	0.194869	1	1.654940797	5	0.541243207	2	1.068696	4	1.115378661	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06553|2.85885e-86|hsa:29802|VPREB3, 8HS20, N27C7-2; pre-B lymphocyte 3; K06553 pre-B lymphocyte gene (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain	Pre-B lymphocyte protein 3 (Precursor) GN=VPREB3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: pre-B lymphocyte protein 3 [Oryctolagus cuniculus]
ENSG00000128228(SDF2L1)	--	45.3995	520	29.6725	359	44.4347	543	51.8815	617	50.905	584	37.5761	435	0.943921706	0.215341961	normal	0.030795507	0.678297063	normal	0.86302355	-0.327207905	normal	0.655552492	0.180561704	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[R]	General function prediction only	MIR domain	Stromal cell-derived factor 2-like protein 1 (Precursor) GN=SDF2L1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: stromal cell-derived factor 2-like 1 [Canis lupus familiaris]
ENSG00000128242(GAL3ST1)	--	5.915758411	148	2.985291836	75	5.360595133	120	10.06723392	246	10.55978366	247	8.085326482	196	0.116759774	0.696565498	normal	3.27E-10	1.678404187	up	0.198866618	0.692632091	normal	0.000224818	0.984768924	normal	--	--	Molecular Function: galactosylceramide sulfotransferase activity (GO:0001733);; Cellular Component: Golgi apparatus (GO:0005794);; Biological Process: glycolipid biosynthetic process (GO:0009247);; Cellular Component: integral component of membrane (GO:0016021);; 	"K01019|0|hsa:9514|GAL3ST1, CST; galactose-3-O-sulfotransferase 1 (EC:2.8.2.11); K01019 galactosylceramide sulfotransferase [EC:2.8.2.11] (A)"	Ether lipid metabolism (ko00565);; Sphingolipid metabolism (ko00600)	--	--	Galactose-3-O-sulfotransferase	Galactosylceramide sulfotransferase GN=GAL3ST1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: galactosylceramide sulfotransferase isoform X4 [Sus scrofa]
ENSG00000128245(YWHAH)	--	62.48646587	2132	65.40914712	2229	62.71447052	2152	65.66058206	2239	52.24028964	1769	48.9406215	1667	0.987281451	0.039786847	normal	0.866896189	-0.354618383	normal	0.816418158	-0.376414017	normal	0.214113751	-0.220891939	normal	[T]	Signal transduction mechanisms	--	"K16198|4.55949e-180|ptr:458778|YWHAH; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta; K16198 14-3-3 protein gamma/eta (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; Hippo signaling pathway (ko04390);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein	14-3-3 protein eta GN=YWHAH OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: 14-3-3 protein eta [Ochotona princeps]
ENSG00000128250(RFPL1)	--	0	0	0	0	0	0	0	0	0.07526	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"RFPL defining motif (RDM);; SPRY domain;; zinc finger of C3HC4-type, RING;; SPRY-associated domain"	Ret finger protein-like 1 GN=RFPL1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ret finger protein-like 3 [Galeopterus variegatus]
ENSG00000128253(RFPL2)	--	0.391308635	15	0.073235084	2	0.1227389	3	0.201174764	9	0.322283172	11	0.798004769	26	--	--	--	--	--	--	0.016723413	2.601471426	normal	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"RFPL defining motif (RDM);; SPRY domain;; zinc finger of C3HC4-type, RING;; SPRY-associated domain"	Ret finger protein-like 2 GN=RFPL2 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ret finger protein-like 3 [Galeopterus variegatus]
ENSG00000128266(GNAZ)	--	4.734967846	324	4.474969341	330	4.0856598	257	1.7987065	113	2.447438497	149	1.440533057	98	1.91E-10	-1.537564774	down	4.79E-06	-1.16045111	down	1.42E-07	-1.385490453	down	4.56E-09	-1.361256876	down	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04535|0|ptr:458693|GNAZ; guanine nucleotide binding protein (G protein), alpha z polypeptide; K04535 guanine nucleotide-binding protein G(z) subunit alpha (A)"	Long-term depression (ko04730)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family	Guanine nucleotide-binding protein G(z) subunit alpha GN=GNAZ OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(z) subunit alpha [Canis lupus familiaris] 
ENSG00000128268(MGAT3)	--	1.196859712	96	0.545602799	44	0.606227384	61	0.116656693	11	0.3722655	36	0.084362708	8	2.08E-12	-2.988510896	down	0.972145109	-0.29953155	normal	3.06E-07	-2.72380763	down	0.018104651	-1.890734653	normal	--	--	"Molecular Function: beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity (GO:0003830);; Biological Process: protein N-linked glycosylation (GO:0006487);; Cellular Component: membrane (GO:0016020);; "	"K00737|0|hsa:4248|MGAT3, GNT-III, GNT3; mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase (EC:2.4.1.144); K00737 beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.144] (A)"	N-Glycan biosynthesis (ko00510)	--	--	Glycosyltransferase family 17	"Beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase GN=MGAT3 OS=Homo sapiens (Human) PE=2 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase isoform X2 [Canis lupus familiaris]"
ENSG00000128271(ADORA2A)	--	0.778370956	41	1.161310484	50	0.773894241	43	0.583975415	25	0.63474178	29	1.667313	53	0.91538366	-0.71010667	normal	0.82622581	-0.776107346	normal	0.970041269	0.284342232	normal	0.624077398	-0.343691799	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04266|0|hsa:135|ADORA2A, A2aR, ADORA2, RDC8; adenosine A2a receptor; K04266 adenosine receptor A2a (A)"	Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Vascular smooth muscle contraction (ko04270);; Parkinson's disease (ko05012);; Alcoholism (ko05034)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Adenosine receptor A2a GN=ADORA2A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: adenosine receptor A2a isoform X1 [Panthera tigris altaica] 
ENSG00000128272(ATF4)	--	276.0013537	6640	281.6337035	6769	266.3370502	6416	203.5429935	4958	212.2303634	5071	335.6742474	8143	0.701889723	-0.452135668	normal	0.772887328	-0.437985515	normal	0.950010092	0.335524461	normal	0.753839695	-0.145386151	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K04374|0|hsa:468|ATF4, CREB-2, CREB2, TAXREB67, TXREB; activating transcription factor 4; K04374 cyclic AMP-dependent transcription factor ATF-4 (A)"	MAPK signaling pathway (ko04010);; cGMP-PKG signaling pathway (ko04022);; Protein processing in endoplasmic reticulum (ko04141);; PI3K-Akt signaling pathway (ko04151);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Thyroid hormone synthesis (ko04918);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper	Cyclic AMP-dependent transcription factor ATF-4 GN=ATF4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: cyclic AMP-dependent transcription factor ATF-4 [Mustela putorius furo]
ENSG00000128274(A4GALT)	--	7.186995595	299	5.1541994	226	5.091868297	208	6.15533608	255	4.781526605	188	3.38583185	140	0.924749799	-0.25903725	normal	0.91787494	-0.284922928	normal	0.474242163	-0.574324741	normal	0.443626596	-0.353671974	normal	--	--	--	"K01988|0|hsa:53947|A4GALT, A14GALT, A4GALT1, Gb3S, P(k), P1, P1PK, PK; alpha 1,4-galactosyltransferase (EC:2.4.1.228); K01988 lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228] (A)"	Glycosphingolipid biosynthesis - globo series (ko00603)	[G]	Carbohydrate transport and metabolism	"Alpha 1,4-glycosyltransferase conserved region;; Glycosyltransferase sugar-binding region containing DXD motif"	Lactosylceramide 4-alpha-galactosyltransferase GN=A4GALT OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: lactosylceramide 4-alpha-galactosyltransferase [Ceratotherium simum simum]
ENSG00000128283(CDC42EP1)	--	18.651415	818	14.53647113	626	14.86976372	659	23.15260302	1027	21.55550843	947	20.828353	919	0.902595643	0.296932556	normal	0.130105166	0.574639093	normal	0.465096915	0.470576439	normal	0.007914568	0.438473895	normal	--	--	--	--	--	--	--	Cdc42 effector;; P21-Rho-binding domain	Cdc42 effector protein 1 GN=CDC42EP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cdc42 effector protein 1 [Galeopterus variegatus] 
ENSG00000128284(APOL3)	--	0.031118998	1	0	0	0	0	0.083929646	4	0.129350726	4	0.06068271	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K14480|0|hsa:80833|APOL3, APOLIII, CG121; apolipoprotein L, 3; K14480 apolipoprotein L (A)"	--	--	--	Apolipoprotein L	Apolipoprotein L3 GN=APOL3 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: apolipoprotein L3-like isoform X1 [Equus caballus] 
ENSG00000128294(TPST2)	--	5.854627035	211	4.051967418	150	4.586743758	160	8.934216321	313	7.701453663	282	4.491243252	169	0.43607038	0.534871348	normal	0.004309421	0.882713972	normal	0.965795727	0.070015924	normal	0.255166606	0.529318629	normal	[R]	General function prediction only	Molecular Function: sulfotransferase activity (GO:0008146);; 	K01021|0|nle:100606069|TPST2; tyrosylprotein sulfotransferase 2; K01021 protein-tyrosine sulfotransferase [EC:2.8.2.20] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase family;; Sulfotransferase domain	Protein-tyrosine sulfotransferase 2 GN=TPST2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-tyrosine sulfotransferase 2 [Galeopterus variegatus]
ENSG00000128298(BAIAP2L2)	--	1.073874064	43	0.496331989	19	1.423526392	54	2.754110291	114	3.850603301	150	3.629033089	144	0.0005949	1.345193659	up	2.22E-16	2.864344763	up	4.26E-05	1.382126504	up	1.91E-07	1.795205726	up	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: plasma membrane organization (GO:0007009);; 	--	--	--	--	IRSp53/MIM homology domain;; Variant SH3 domain;; Variant SH3 domain	Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 GN=BAIAP2L2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 2 [Orcinus orca]
ENSG00000128309(MPST)	--	57.02072215	1219	47.24064358	1089	49.71427637	1171	46.08266731	1017	56.972793	1223	48.24122124	1128	0.912723196	-0.291807366	normal	0.971922318	0.145802754	normal	0.979818225	-0.062183621	normal	0.789656084	-0.067546568	normal	[P]	Inorganic ion transport and metabolism	--	K01011|0|pps:100989726|MPST; mercaptopyruvate sulfurtransferase; K01011 thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] (A)	Cysteine and methionine metabolism (ko00270);; Sulfur metabolism (ko00920);; Sulfur relay system (ko04122)	[V]	Defense mechanisms	Rhodanese-like domain	3-mercaptopyruvate sulfurtransferase GN=MPST OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: 3-mercaptopyruvate sulfurtransferase isoform 1 [Ceratotherium simum simum]
ENSG00000128311(TST)	--	33.75426002	679	31.08804378	657	35.03775	703	25.79202013	547	32.39441733	643	35.11780681	691	0.840795999	-0.34183921	normal	0.972792311	-0.052379315	normal	0.974986484	-0.033058689	normal	0.5762306	-0.136726922	normal	[P]	Inorganic ion transport and metabolism	--	"K01011|0|hsa:7263|TST, RDS; thiosulfate sulfurtransferase (rhodanese) (EC:2.8.1.1); K01011 thiosulfate/3-mercaptopyruvate sulfurtransferase [EC:2.8.1.1 2.8.1.2] (A)"	Cysteine and methionine metabolism (ko00270);; Sulfur metabolism (ko00920);; Sulfur relay system (ko04122)	[V]	Defense mechanisms	Rhodanese-like domain	Thiosulfate sulfurtransferase GN=TST OS=Homo sapiens (Human) PE=1 SV=4	V	Defense mechanisms	PREDICTED: thiosulfate sulfurtransferase [Tupaia chinensis] 
ENSG00000128335(APOL2)	--	9.063286	480	10.434973	563	12.79477	656	20.99581728	1041	12.9267785	601	20.645574	1040	1.01E-07	1.083620509	up	0.970339597	0.072614711	normal	0.021881501	0.655314211	normal	0.13174031	0.637585015	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K14480|0|pps:100982122|APOL2; apolipoprotein L, 2; K14480 apolipoprotein L (A)"	--	--	--	Apolipoprotein L	Apolipoprotein L2 GN=APOL2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: apolipoprotein L2-like [Galeopterus variegatus]
ENSG00000128340(RAC2)	--	0	0	0	0	0.544013674	4	0.098826692	2	0.237359166	5	0.079727056	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07860|3.3001e-140|mcf:102137056|RAC2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); K07860 Ras-related C3 botulinum toxin substrate 2 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Natural killer cell mediated cytotoxicity (ko04650);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Choline metabolism in cancer (ko05231);; Viral myocarditis (ko05416)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Ras-related C3 botulinum toxin substrate 2 (Precursor) GN=RAC2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras-related C3 botulinum toxin substrate 2 [Sorex araneus]
ENSG00000128342(LIF)	--	35.97904	2999	45.7078	3367	37.38464	3122	29.6641	2416	29.14164	2426	38.15834	3153	0.896826665	-0.342497383	normal	0.439806646	-0.494048037	normal	0.990542594	0.005960318	normal	0.158734736	-0.267471645	normal	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; 	K05419|7.22327e-122|ptr:736309|LIF; leukemia inhibitory factor; K05419 leukemia inhibitory factor (A)	Cytokine-cytokine receptor interaction (ko04060);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; TNF signaling pathway (ko04668)	--	--	LIF / OSM family	Leukemia inhibitory factor (Precursor) GN=LIF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: leukemia inhibitory factor [Galeopterus variegatus]
ENSG00000128346(C22orf23)	--	1.948556763	66	2.72061643	90	1.724711335	57	3.122160464	103	3.435011068	114	1.651540013	55	0.748868309	0.600012643	normal	0.935860964	0.314899684	normal	0.977014306	-0.058248385	normal	0.614411852	0.329542298	normal	--	--	--	--	--	--	--	Uncharacterised protein family (UPF0193)	UPF0193 protein EVG1 GN=C22orf23 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0193 protein EVG1 isoform X1 [Mustela putorius furo] 
ENSG00000128383(APOBEC3A)	--	19.11931	470	16.27282	419	18.83175	472	8.75808	221	7.932776	195	10.833643	267	1.28E-06	-1.114003135	down	3.10E-06	-1.118834011	down	0.001847663	-0.826668604	normal	2.06E-07	-1.01525191	down	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	K18750|1.73109e-149|hsa:100913187|APOBEC3A_B; APOBEC3A and APOBEC3B deletion hybrid; K18750 C->U-editing enzyme APOBEC3 [EC:3.5.4.-] (A)	--	--	--	APOBEC-like C-terminal domain;; APOBEC-like N-terminal domain	DNA dC-	L	"Replication, recombination and repair"	PREDICTED: DNA dC-
ENSG00000128394(APOBEC3F)	--	2.637486297	147	2.832561168	155	2.800162121	123	1.721682477	93	2.891991755	101	2.375136778	129	0.36570529	-0.682296513	normal	0.467756247	-0.631644071	normal	0.967912725	0.059704466	normal	0.27284134	-0.416503656	normal	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	K18750|0|ggo:101134601|DNA dC->dU-editing enzyme APOBEC-3G-like isoform 1; K18750 C->U-editing enzyme APOBEC3 [EC:3.5.4.-] (A)	--	--	--	APOBEC-like N-terminal domain;; APOBEC-like C-terminal domain;; Cytidine and deoxycytidylate deaminase zinc-binding region	DNA dC-	L	"Replication, recombination and repair"	PREDICTED: DNA dC-
ENSG00000128408(RIBC2)	--	2.609202	151	2.407783573	137	2.339903327	131	1.672061178	95	2.547909322	137	1.821155	94	0.329364491	-0.690439828	normal	0.966930018	-0.021192625	normal	0.823445009	-0.480546377	normal	0.329651186	-0.383241853	normal	--	--	--	--	--	--	--	RIB43A	RIB43A-like with coiled-coils protein 2 GN=RIBC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RIB43A-like with coiled-coils protein 2 [Ceratotherium simum simum]
ENSG00000128422(KRT17)	--	0.168584692	3	0	0	0	0	0	0	0.03451912	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3872|KRT17, K17, PC, PC2, PCHC1; keratin 17; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 17 GN=KRT17 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 17 [Mustela putorius furo] "
ENSG00000128463(EMC4)	--	112.5379	1607	104.782829	1537	110.0038	1586	122.647856	1769	109.941103	1554	115.54713	1658	0.981550594	0.107633753	normal	0.983964653	-0.005551787	normal	0.983946869	0.055707838	normal	0.836180419	0.05318376	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1077)	ER membrane protein complex subunit 4 GN=EMC4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ER membrane protein complex subunit 4 [Trichechus manatus latirostris]
ENSG00000128482(RNF112)	--	0.506873125	33	0.501262226	34	0.262651716	17	0.43358859	6	0.377052215	9	0.076248614	5	0.011240958	-2.223165208	normal	0.086567558	-1.775671315	normal	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	"Guanylate-binding protein, N-terminal domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 112 GN=RNF112 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 112 [Galeopterus variegatus]
ENSG00000128487(SPECC1)	--	25.96122704	2135	28.79000418	2528	29.66146454	2297	27.50872644	2499	30.98881548	2928	35.07661535	3136	0.974716837	0.196151997	normal	0.978202151	0.190386631	normal	0.649493897	0.440634014	normal	0.109960714	0.278483282	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Calponin homology (CH) domain;; CAMSAP CH domain	Cytospin-B GN=SPECC1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: cytospin-B [Equus caballus]
ENSG00000128510(CPA4)	--	24.36563843	859	9.276828108	440	22.20857458	912	21.69629464	936	14.4463079	560	13.2143986	545	0.974711943	0.092859	normal	0.866240649	0.325502992	normal	0.002725946	-0.749443307	normal	0.876094069	-0.137739825	normal	[E]	Amino acid transport and metabolism	Molecular Function: carboxypeptidase activity (GO:0004180);; Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	K08637|0|ptr:463727|CPA4; carboxypeptidase A4; K08637 carboxypeptidase A4 [EC:3.4.17.-] (A)	--	[S]	Function unknown	Zinc carboxypeptidase;; Carboxypeptidase activation peptide	Carboxypeptidase A4 (Precursor) GN=CPA4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carboxypeptidase A4 isoform X1 [Canis lupus familiaris]
ENSG00000128512(DOCK4)	--	4.2660108	638	2.7077178	387	4.2564194	562	6.713355443	942	6.360444939	919	6.2041703	867	0.234467796	0.530281519	normal	2.08E-09	1.22310949	up	0.05748382	0.615826092	normal	1.99E-05	0.76037992	normal	--	--	--	K17697|0|nle:100604748|DOCK4; dedicator of cytokinesis 4; K17697 dedicator of cytokinesis protein 4 (A)	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	C2 domain in Dock180 and Zizimin proteins;; Dedicator of cytokinesis	Dedicator of cytokinesis protein 4 GN=DOCK4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 4 isoform X6 [Bos taurus]
ENSG00000128513(POT1)	--	8.621778879	486	6.709709264	399	8.816154165	504	9.61824105	472	8.222431068	409	7.383282956	452	0.968890953	-0.072768264	normal	0.968902621	0.014232261	normal	0.956772345	-0.164869736	normal	0.800675307	-0.080474122	normal	--	--	"Biological Process: telomere maintenance (GO:0000723);; Cellular Component: nuclear chromosome, telomeric region (GO:0000784);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: single-stranded telomeric DNA binding (GO:0043047);; "	K11109|0|ggo:101153621|POT1; protection of telomeres protein 1; K11109 protection of telomeres protein 1 (A)	--	[R]	General function prediction only	Telomeric single stranded DNA binding POT1/CDC13	Protection of telomeres protein 1 GN=POT1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protection of telomeres protein 1 isoform X1 [Canis lupus familiaris] 
ENSG00000128524(ATP6V1F)	--	140.181515	1333	134.925313	1325	146.4085	1445	139.193234	1364	134.09805	1268	175.831698	1707	0.98291046	0.002331943	normal	0.979582438	-0.084765263	normal	0.957402716	0.231878607	normal	0.845186733	0.060284321	normal	[C]	Energy production and conversion	Biological Process: ion transmembrane transport (GO:0034220);; 	"K02151|2.50562e-103|hsa:9296|ATP6V1F, ATP6S14, VATF, Vma7; ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F (EC:3.6.3.14); K02151 V-type H+-transporting ATPase subunit F (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase (F/14-kDa) subunit	V-type proton ATPase subunit F GN=ATP6V1F OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit F isoform X1 [Chrysochloris asiatica]
ENSG00000128534(LSM8)	--	30.127458	725	29.7882549	750	28.510886	724	28.942559	755	25.8346374	686	29.84408555	768	0.975719798	0.027606057	normal	0.964101911	-0.149792629	normal	0.973715908	0.076669662	normal	0.970604033	-0.014675959	normal	[K]	Transcription	--	"K12627|5.14748e-62|tup:102469267|LSM8, NAA38; LSM8 homolog, U6 small nuclear RNA associated; K12627 U6 snRNA-associated Sm-like protein LSm8 (A)"	RNA degradation (ko03018);; Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm8 GN=LSM8 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	U6 snRNA-associated Sm-like protein LSm8 [Bos taurus]
ENSG00000128536(CDHR3)	--	0.062593674	3	0.273182461	19	0.073258376	5	0.032456884	2	0.020244413	0	0.062137111	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K16503|0|pps:100986386|CDHR3; cadherin-related family member 3; K16503 cadherin-related family member 3 (A)	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Cadherin-related family member 3 (Precursor) GN=CDHR3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: cadherin-related family member 3 [Galeopterus variegatus]
ENSG00000128563(PRKRIP1)	--	7.759890841	535	8.838138243	600	8.797981228	590	9.220113	573	12.46409687	734	9.135485549	592	0.970709036	0.067975341	normal	0.91936203	0.268777637	normal	0.973589888	-0.003400519	normal	0.654520284	0.117716094	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1168)	PRKR-interacting protein 1 GN=PRKRIP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: PRKR-interacting protein 1 [Tupaia chinensis] 
ENSG00000128564(VGF)	--	1.148452842	54	0.83117956	40	0.981133335	47	1.373604624	53	1.046208013	45	1.10267505	45	0.977968691	-0.056185622	normal	0.977959067	0.143385504	normal	0.979398468	-0.068765728	normal	1	-0.001356751	normal	--	--	--	--	--	--	--	--	Antimicrobial peptide VGF[554-577] (Precursor) GN=VGF OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: neurosecretory protein VGF, partial [Tupaia chinensis]"
ENSG00000128567(PODXL)	--	9.081080235	1061	6.871171287	827	8.285400142	1037	37.61880596	4677	30.92403319	3845	16.26816108	2016	0	2.10774002	up	0	2.193553123	up	2.40E-06	0.949776876	normal	0.003568253	1.825883265	up	--	--	--	"K06817|0|hsa:5420|PODXL, Gp200, PC, PCLP, PCLP-1; podocalyxin-like; K06817 podocalyxin-like (A)"	--	--	--	CD34/Podocalyxin family	Podocalyxin (Precursor) GN=PODXL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	podocalyxin precursor [Canis lupus familiaris] 
ENSG00000128573(FOXP2)	--	0.095438781	3	0.118050906	7	0.076529525	3	0.048372465	5	0.154116798	13	0.123686697	14	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09409|0|cge:100762481|Foxp2; forkhead box P2; K09409 forkhead box protein P (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein P2 GN=FOXP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: forkhead box protein P2 isoform X10 [Leptonychotes weddellii]
ENSG00000128578(STRIP2)	--	3.359013	316	3.870513	311	3.736297419	343	11.253373	953	10.296275	907	15.922976	1418	1.44E-15	1.557145135	up	2.51E-14	1.518236221	up	0	2.034499162	up	1.36E-05	1.73691416	up	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF3402);; N1221-like protein	Striatin-interacting protein 2 GN=STRIP2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: striatin-interacting protein 2 isoform 2 [Dasypus novemcinctus]
ENSG00000128581(IFT22)	--	25.69660824	596	25.6070873	617	23.06447627	565	27.00254	670	26.63922289	679	25.88113403	645	0.964860237	0.137681627	normal	0.967579914	0.116442398	normal	0.955309827	0.182299864	normal	0.557156575	0.143993942	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07935|1.31758e-105|pps:100996132|IFT22, RABL5; intraflagellar transport 22; K07935 Rab-like protein 5 (A)"	--	--	--	Ras family;; ADP-ribosylation factor family;; Miro-like protein;; Signal recognition particle receptor beta subunit	Intraflagellar transport protein 22 homolog GN=IFT22 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab-like protein 5 isoform X1 [Tupaia chinensis] 
ENSG00000128585(MKLN1)	--	18.87449694	2341	22.86985913	2733	22.92725023	2529	17.98562201	2431	16.28291278	2162	18.70760061	2524	0.988301744	0.023577511	normal	0.871853929	-0.359321375	normal	0.988875903	-0.011139901	normal	0.58351055	-0.116468645	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	"Muskelin N-terminus;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; F5/8 type C domain;; Kelch motif"	Muskelin GN=MKLN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: muskelin isoform X1 [Vicugna pacos] 
ENSG00000128590(DNAJB9)	--	6.9241	258	11.203	423	7.05155	262	8.29378	314	9.53552	356	19.3536	724	0.927971014	0.251203537	normal	0.915408208	-0.269156561	normal	9.47E-13	1.4528708	up	0.549745978	0.544678587	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09515|1.66793e-148|hsa:4189|DNAJB9, ERdj4, MDG-1, MDG1, MST049, MSTP049; DnaJ (Hsp40) homolog, subfamily B, member 9; K09515 DnaJ homolog subfamily B member 9 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily B member 9 (Precursor) GN=DNAJB9 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 9 [Condylura cristata]
ENSG00000128591(FLNC)	--	0.468778245	101	0.27266752	60	0.4318394	95	0.820625334	178	1.5336866	332	0.311690378	68	0.101397665	0.777670412	normal	0	2.417678758	up	0.881292025	-0.481580893	normal	0.370595206	1.152940992	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	K04437|0|ggo:101142657|FLNC; filamin-C isoform 1; K04437 filamin (A)	MAPK signaling pathway (ko04010);; Focal adhesion (ko04510);; Salmonella infection (ko05132);; Proteoglycans in cancer (ko05205)	[Z]	Cytoskeleton	Filamin/ABP280 repeat;; Calponin homology (CH) domain;; Y_Y_Y domain;; Bacterial Ig-like domain (group 1);; YtkA-like;; Bacterial Ig-like domain (group 3);; emp24/gp25L/p24 family/GOLD;; Protein of unknown function (DUF1214)	Filamin-C GN=FLNC OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: filamin-C isoformX1 [Sus scrofa]
ENSG00000128594(LRRC4)	--	0	0	0.026681839	2	0.013170963	0	0.013406284	1	0.039321492	2	0.13333957	10	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K16351|0|ptr:739898|LRRC4; leucine rich repeat containing 4; K16351 netrin-G2 ligand (A)	Axon guidance (ko04360);; Cell adhesion molecules (CAMs) (ko04514)	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Immunoglobulin I-set domain;; Leucine rich repeat;; Immunoglobulin V-set domain;; Immunoglobulin domain	Leucine-rich repeat-containing protein 4 (Precursor) GN=LRRC4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 4 [Pteropus alecto] 
ENSG00000128595(CALU)	--	117.3921918	6644	99.14407807	5816	109.0611677	6084	125.71202	7399	111.812445	6528	122.7061049	7074	0.993090441	0.12441869	normal	0.991180059	0.145151591	normal	0.986804315	0.209166365	normal	0.451500224	0.158114589	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair	Calumenin (Precursor) GN=CALU OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: calumenin isoform 1 [Trichechus manatus latirostris] 
ENSG00000128596(CCDC136)	--	1.248330283	143	1.371460989	137	1.866869839	142	4.11581606	120	1.581662406	152	1.399555577	121	0.937410515	-0.28051776	normal	0.961412254	0.127136117	normal	0.948505922	-0.236444392	normal	0.810489609	-0.123720864	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 136 GN=CCDC136 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 136 isoform X1 [Equus caballus]
ENSG00000128602(SMO)	--	17.87662	1230	16.86103	1188	15.47983	1093	13.95361	959	15.59704	1064	15.01921	1034	0.751793734	-0.389335424	normal	0.96533509	-0.180220676	normal	0.977339327	-0.088223138	normal	0.234769545	-0.220862015	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	"K06226|0|hsa:6608|SMO, FZD11, Gx, SMOH; smoothened, frizzled class receptor; K06226 smoothened (A)"	Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain;; Slime mold cyclic AMP receptor	Smoothened homolog (Precursor) GN=SMO OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: smoothened homolog isoform X1 [Equus przewalskii]
ENSG00000128604(IRF5)	--	7.604966851	377	7.64926456	388	7.599355212	391	6.83417672	327	6.607675655	307	6.991668914	370	0.933381451	-0.235076366	normal	0.834460529	-0.357673337	normal	0.9658616	-0.087586484	normal	0.402102147	-0.224202374	normal	--	--	"Molecular Function: regulatory region DNA binding (GO:0000975);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09446|0|pps:100990704|IRF5; interferon regulatory factor 5; K09446 interferon regulatory factor 5 (A)	Toll-like receptor signaling pathway (ko04620)	--	--	Interferon-regulatory factor 3;; Interferon regulatory factor transcription factor	Interferon regulatory factor 5 GN=IRF5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: interferon regulatory factor 5 [Physeter catodon]
ENSG00000128606(LRRC17)	--	0.0535278	2	0.0825536	3	0	0	0.196627	2	0.0264148	0	0.1683586	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 17 (Precursor) GN=LRRC17 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 17 [Panthera tigris altaica]
ENSG00000128607(KLHDC10)	--	8.840809391	918	10.53633518	1104	9.623654991	991	10.11590261	1055	11.31598948	1170	10.0928268	1046	0.965557031	0.169579779	normal	0.979191694	0.062258952	normal	0.977988825	0.069531159	normal	0.682408658	0.097301337	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch domain-containing protein 10 GN=KLHDC10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: kelch domain-containing protein 10 [Orycteropus afer afer]
ENSG00000128609(NDUFA5)	--	32.8401686	698	30.91532772	624	27.83541594	588	37.59868283	804	37.07202241	794	34.54786981	711	0.960518113	0.17278163	normal	0.868019924	0.325465697	normal	0.921123356	0.265121001	normal	0.207570743	0.251984533	normal	--	--	"Cellular Component: mitochondrial inner membrane (GO:0005743);; Molecular Function: oxidoreductase activity, acting on NAD(P)H (GO:0016651);; Biological Process: respiratory electron transport chain (GO:0022904);; "	"K03949|5.75862e-78|ptr:463686|NDUFA5; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5; K03949 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 5 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	ETC complex I subunit conserved region	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 GN=NDUFA5 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 isoform X3 [Canis lupus familiaris]
ENSG00000128626(MRPS12)	--	143.759	2221	124.8678	1983	143.0286	2290	143.8168	2236	150.4754	2318	123.5976	1913	0.987740666	-0.021106916	normal	0.971831726	0.203625584	normal	0.949284256	-0.267608533	normal	0.923805752	-0.027418499	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02950|3.5956e-83|hsa:6183|MRPS12, MPR-S12, MT-RPS12, RPMS12, RPS12, RPSM12; mitochondrial ribosomal protein S12; K02950 small subunit ribosomal protein S12 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S12/S23	"28S ribosomal protein S12, mitochondrial (Precursor) GN=MRPS12 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S12, mitochondrial [Galeopterus variegatus]"
ENSG00000128641(MYO1B)	--	50.30023928	4771	55.98331786	5316	50.78111705	4767	32.99587279	3171	32.504162	3051	36.50535293	3483	0.044026459	-0.619939307	normal	0.000187221	-0.822172562	normal	0.616441037	-0.46087082	normal	8.64E-06	-0.635106763	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	K10356|0|ptr:459835|MYO1B; myosin IB; K10356 myosin I (A)	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; IQ calmodulin-binding motif	Unconventional myosin-Ib GN=MYO1B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: unconventional myosin-Ib isoform X1 [Tupaia chinensis]
ENSG00000128645(HOXD1)	--	0.070213	2	0	0	0	0	0	0	0.201771	5	0.137392	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09301|2.3779e-167|hsa:3231|HOXD1, HOX4, HOX4G, Hox-4.7; homeobox D1; K09301 homeobox protein HoxA/B/D1 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-D1 GN=HOXD1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox protein Hox-D1 [Ceratotherium simum simum]
ENSG00000128652(HOXD3)	--	0.098207212	4	0.024677631	1	1.00883	2	0.0490801	2	0.023642565	0	0.048006226	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09303|0|hsa:3232|HOXD3, HOX1D, HOX4, HOX4A, Hox-4.1; homeobox D3; K09303 homeobox protein HoxA/B/D3 (A)"	--	[R]	General function prediction only	Domain of unknown function (DUF4074);; Homeobox domain	Homeobox protein Hox-D3 GN=HOXD3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-D3 [Equus caballus] 
ENSG00000128654(MTX2)	--	34.33620215	683	33.50564323	677	36.88951166	737	20.86523822	426	24.68976754	488	24.42985438	489	0.010331876	-0.709822165	normal	0.420872212	-0.49239945	normal	0.089539453	-0.598602818	normal	0.000489539	-0.600404674	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: protein targeting to mitochondrion (GO:0006626);; 	K17776|0|pps:100989012|MTX2; metaxin 2; K17776 metaxin (A)	--	[MU]	"Cell wall/membrane/envelope biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	"Glutathione S-transferase, C-terminal domain;; Tom37 C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Outer mitochondrial membrane transport complex protein"	Metaxin-2 GN=MTX2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: metaxin-2 [Ochotona princeps] 
ENSG00000128655(PDE11A)	--	0.526541177	88	0.357281305	64	0.385054059	63	0.94031463	101	0.938913614	135	0.685473098	116	0.965335209	0.165253047	normal	0.011825681	1.038132795	normal	0.16380217	0.857024824	normal	0.071107153	0.690302823	normal	[T]	Signal transduction mechanisms	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; "	"K13298|0|ptr:740616|PDE11A; phosphodiesterase 11A; K13298 dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35] (A)"	Purine metabolism (ko00230);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; GAF domain;; GAF domain;; GAF domain	"Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A GN=PDE11A OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A-like [Tupaia chinensis]"
ENSG00000128656(CHN1)	--	8.841313809	391	10.56346135	450	9.820413915	447	7.413503256	293	7.861555936	324	8.384885151	373	0.65078075	-0.445071913	normal	0.481931659	-0.493394147	normal	0.9161976	-0.268395179	normal	0.070713733	-0.400008135	normal	--	--	Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; SH2 domain	N-chimaerin GN=CHN1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: N-chimaerin isoform X1 [Elephantulus edwardii]
ENSG00000128683(GAD1)	--	0.43414733	17	0.333727843	7	0.109438111	2	0.486851251	17	0.3897593	13	0.540511288	10	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: carboxy-lyase activity (GO:0016831);; Biological Process: carboxylic acid metabolic process (GO:0019752);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K01580|0|hsa:2571|GAD1, CPSQ1, GAD, SCP; glutamate decarboxylase 1 (brain, 67kDa) (EC:4.1.1.15); K01580 glutamate decarboxylase [EC:4.1.1.15] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; beta-Alanine metabolism (ko00410);; Taurine and hypotaurine metabolism (ko00430);; Butanoate metabolism (ko00650);; GABAergic synapse (ko04727);; Type I diabetes mellitus (ko04940)"	[E]	Amino acid transport and metabolism	Pyridoxal-dependent decarboxylase conserved domain;; Aminotransferase class-V;; Beta-eliminating lyase	Glutamate decarboxylase 1 GN=GAD1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: glutamate decarboxylase 1 isoform 1 [Dasypus novemcinctus] 
ENSG00000128694(OSGEPL1)	--	8.607363	253	5.763024059	173	6.459248037	186	3.935085377	110	4.226439381	129	2.82097983	89	6.19E-06	-1.220883655	down	0.813482313	-0.44035256	normal	0.001253638	-1.058988306	down	0.002947942	-0.921627619	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K01409|0|hsa:64172|OSGEPL1, Qri7; O-sialoglycoprotein endopeptidase-like 1 (EC:2.6.99.4); K01409 N6-L-threonylcarbamoyladenine synthase [EC:2.3.1.234] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycoprotease family	"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03179} (Precursor) OS=Homo sapiens (Human) PE=2 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial isoform X3 [Tupaia chinensis]"
ENSG00000128699(ORMDL1)	--	33.3889245	659	37.45589318	701	31.82808522	652	24.92300113	456	27.11756002	494	25.244583	486	0.177730405	-0.560496103	normal	0.296980679	-0.524973424	normal	0.633420502	-0.431044768	normal	0.004544316	-0.507631581	normal	[S]	Function unknown	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	ORMDL family	ORM1-like protein 1 GN=ORMDL1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: ORM1-like protein 1 [Elephantulus edwardii]
ENSG00000128708(HAT1)	--	42.9908	1158	42.8839	1147	43.6703	1155	23.7141	643	22.9194	614	20.2257	546	5.26E-05	-0.877989377	normal	2.12E-05	-0.921292856	normal	5.82E-08	-1.087091915	down	4.12E-11	-0.962028414	normal	--	--	Biological Process: chromatin organization (GO:0006325);; 	K11303|0|ptr:459737|HAT1; histone acetyltransferase 1; K11303 histone acetyltransferase 1 [EC:2.3.1.48] (A)	Alcoholism (ko05034)	[B]	Chromatin structure and dynamics	Histone acetyl transferase HAT1 N-terminus	Histone acetyltransferase type B catalytic subunit GN=HAT1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase type B catalytic subunit isoform 1 [Ceratotherium simum simum]
ENSG00000128709(HOXD9)	--	0.969477566	114	0.715023577	69	0.944787983	79	4.978693442	826	5.537878509	932	4.105582532	687	0	2.809875845	up	0	3.705542954	up	0	3.087997036	up	6.80E-34	3.200449175	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K09294|4.95462e-113|hsa:3235|HOXD9, HOX4, HOX4C, Hox-4.3, Hox-5.2; homeobox D9; K09294 homeobox protein HoxA/B/C/D9 (A)"	--	[K]	Transcription	Hox9 activation region;; Homeobox domain	Homeobox protein Hox-D9 GN=HOXD9 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	TPA: homeobox D9-like [Bos taurus]
ENSG00000128714(HOXD13)	--	0.640534	21	0.388676	13	0.295445	9	0.0300924	1	0	0	0.120387	4	0.012622432	-3.171835539	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09298|0|hsa:3239|HOXD13, BDE, BDSD, HOX4I, SPD; homeobox D13; K09298 homeobox protein HoxA/C/D13 (A)"	--	[K]	Transcription	Homeobox domain;; Hox protein A13 N terminal	Homeobox protein Hox-D13 GN=HOXD13 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-D13 [Mustela putorius furo]
ENSG00000128731(HERC2)	--	16.55159472	5386	16.91776703	5607	18.15246199	5970	18.59822409	6050	18.12269391	5850	19.09953118	6197	0.991283476	0.136851802	normal	0.993694013	0.039770495	normal	0.994114391	0.045536273	normal	0.776634563	0.072368207	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: metal ion binding (GO:0046872);; 	"K10595|0|hsa:8924|HERC2, D15F37S1, MRT38, SHEP1, jdf2, p528; HECT and RLD domain containing E3 ubiquitin protein ligase 2; K10595 E3 ubiquitin-protein ligase HERC2 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[S]	Function unknown	"Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat;; HECT-domain (ubiquitin-transferase);; Mouse development and cellular proliferation protein Cullin-7;; Mib_herc2;; Cytochrome b5-like Heme/Steroid binding domain;; Zinc finger, ZZ type;; Anaphase-promoting complex, subunit 10 (APC10)"	E3 ubiquitin-protein ligase HERC2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase HERC2 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000128739(SNRPN)	--	63.24567524	1717	59.66426353	1621	62.1830544	1704	85.33212801	2290	95.866009	2531	82.83055406	2190	0.801098306	0.384326631	normal	0.044497209	0.620929689	normal	0.862008906	0.353436713	normal	0.002116249	0.454420032	normal	[K]	Transcription	--	K11100|7.06546e-76|cjc:100386895|SNRPN; small nuclear ribonucleoprotein polypeptide N; K11100 small nuclear ribonucleoprotein N (A)	--	[K]	Transcription	LSM domain	Small nuclear ribonucleoprotein-associated protein N GN=SNRPN OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: small nuclear ribonucleoprotein-associated protein N-like isoform 1 [Orcinus orca] 
ENSG00000128789(PSMG2)	--	38.8656	544	36.65423	470	38.30076	517	39.42781	570	40.8335	535	40.33675	561	0.972265675	0.036422509	normal	0.956491405	0.164953844	normal	0.966936415	0.109238228	normal	0.72414429	0.100718196	normal	--	--	--	"K11876|0|hsa:56984|PSMG2, CLAST3, HCCA3, HsT1707, MDS003, PAC2, TNFSF5IP1; proteasome (prosome, macropain) assembly chaperone 2; K11876 proteasome assembly chaperone 2 (A)"	--	[S]	Function unknown	PAC2 family	Proteasome assembly chaperone 2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome assembly chaperone 2 [Myotis brandtii] 
ENSG00000128791(TWSG1)	--	32.57842	1574	32.338261	1543	32.54320094	1541	28.553387	1399	26.86300218	1302	27.742781	1344	0.965711589	-0.200663915	normal	0.939415709	-0.266150805	normal	0.963958946	-0.205409134	normal	0.208862074	-0.224921786	normal	--	--	--	--	--	--	--	Twisted gastrulation (Tsg) protein conserved region	Twisted gastrulation protein homolog 1 (Precursor) GN=TWSG1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: twisted gastrulation protein homolog 1 isoform X1 [Panthera tigris altaica] 
ENSG00000128805(ARHGAP22)	--	3.770857247	214	3.1566159	198	2.613155453	178	2.667835935	154	2.334756974	134	1.928319583	110	0.653673476	-0.501249167	normal	0.484341303	-0.579279719	normal	0.234235896	-0.6950802	normal	0.04941954	-0.590375028	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	RhoGAP domain;; PH domain;; Pleckstrin homology domain	Rho GTPase-activating protein 22 GN=ARHGAP22 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 22 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000128815(WDFY4)	--	0	0	0	0	0	0	0.004748069	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; WD domain, G-beta repeat;; PH domain associated with Beige/BEACH"	WD repeat- and FYVE domain-containing protein 4 GN=WDFY4 OS=Homo sapiens (Human) PE=1 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: WD repeat- and FYVE domain-containing protein 4 isoform X5 [Equus przewalskii] 
ENSG00000128829(EIF2AK4)	--	14.32010675	1557	13.36837401	1535	13.17828155	1489	14.19856364	1623	14.01177757	1605	12.01586222	1368	0.984393746	0.029033731	normal	0.9835845	0.042866782	normal	0.977353293	-0.130428716	normal	0.959389613	-0.017005205	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16196|0|hsa:440275|EIF2AK4, GCN2, PVOD2; eukaryotic translation initiation factor 2 alpha kinase 4 (EC:2.7.11.1); K16196 eukaryotic translation initiation factor 2-alpha kinase 4 [EC:2.7.11.1] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[J]	"Translation, ribosomal structure and biogenesis"	Protein kinase domain;; Protein tyrosine kinase;; RWD domain;; Histidyl-tRNA synthetase;; Anticodon binding domain of tRNAs;; Kinase-like	Eukaryotic translation initiation factor 2-alpha kinase 4 GN=EIF2AK4 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 4 [Tupaia chinensis]
ENSG00000128833(MYO5C)	--	5.368573253	807	6.214032883	927	7.446044148	970	8.972545296	1246	7.095589151	983	9.974194328	1260	0.070664396	0.594913248	normal	0.97700136	0.063095557	normal	0.803910444	0.368570091	normal	0.064959241	0.346631687	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	K10357|0|hsa:55930|MYO5C; myosin VC; K10357 myosin V (A)	--	[Z]	Cytoskeleton	Myosin head (motor domain);; DIL domain;; IQ calmodulin-binding motif	Unconventional myosin-Vc GN=MYO5C OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-Vc [Equus przewalskii]
ENSG00000128849(CGNL1)	--	0.98751365	180	1.091111201	202	1.01483683	186	0.860570669	159	1.061189467	192	0.968546552	176	0.94941228	-0.20791257	normal	0.962416944	-0.093953953	normal	0.964409395	-0.087288933	normal	0.766608589	-0.128979121	normal	--	--	Molecular Function: motor activity (GO:0003774);; Cellular Component: myosin complex (GO:0016459);; 	--	--	--	--	Myosin tail	Cingulin-like protein 1 GN=CGNL1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: cingulin-like 1 isoform X1 [Equus caballus] 
ENSG00000128872(TMOD2)	--	2.119890587	326	2.217948314	321	2.37371431	319	2.881815054	446	2.042721526	313	2.219923347	341	0.703674593	0.419642664	normal	0.965719445	-0.057562556	normal	0.964943574	0.087522502	normal	0.579236144	0.165217515	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: tropomyosin binding (GO:0005523);; Biological Process: pointed-end actin filament capping (GO:0051694);; 	K10370|0|ggo:101138794|TMOD2; tropomodulin-2 isoform 1; K10370 tropomodulin (A)	--	[Z]	Cytoskeleton	Tropomodulin	Tropomodulin-2 GN=TMOD2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tropomodulin-2 isoformX1 [Equus caballus]
ENSG00000128881(TTBK2)	--	2.004998681	318	2.37212473	369	1.860747091	358	2.454158192	470	2.8351315	378	3.166100029	500	0.333734724	0.530680835	normal	0.968257271	0.013285067	normal	0.527551631	0.471982465	normal	0.127056258	0.346262236	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: structural molecule activity (GO:0005198);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: intermediate filament (GO:0005882);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08815|0|hsa:146057|TTBK2, SCA11, TTBK; tau tubulin kinase 2 (EC:2.7.11.1); K08815 tau tubulin kinase [EC:2.7.11.26] (A)"	--	--	--	Intermediate filament protein;; Protein kinase domain;; Protein tyrosine kinase;; Protein kinase domain	Tau-tubulin kinase 2 GN=TTBK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tau-tubulin kinase 2 isoform X1 [Panthera tigris altaica]
ENSG00000128886(ELL3)	--	1.254452	56	1.269769	60	0.9225	43	0.980207403	46	1.202201	53	0.523536	24	0.966982108	-0.305364248	normal	0.970987093	-0.195159135	normal	0.860325017	-0.810916219	normal	0.538241584	-0.393497008	normal	--	--	Biological Process: transcription elongation from RNA polymerase II promoter (GO:0006368);; Cellular Component: transcription elongation factor complex (GO:0008023);; 	K15183|0|hsa:80237|ELL3; elongation factor RNA polymerase II-like 3; K15183 RNA polymerase II elongation factor ELL (A)	--	[K]	Transcription	RNA polymerase II elongation factor ELL;; Occludin homology domain	RNA polymerase II elongation factor ELL3 GN=ELL3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: RNA polymerase II elongation factor ELL3 isoform X2 [Equus przewalskii]
ENSG00000128891(C15orf57)	--	4.832427234	146	4.561790054	111	4.868569934	138	5.326573	151	5.682478174	155	4.761189251	127	0.967874277	0.017566149	normal	0.818635313	0.455014304	normal	0.963683364	-0.126683603	normal	0.831204751	0.111061754	normal	--	--	--	--	--	--	--	Coiled-coil domain containing 32	Uncharacterized protein C15orf57 GN=C15orf57 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C15orf57 homolog isoform X1 [Galeopterus variegatus]
ENSG00000128908(INO80)	--	6.477503816	872	6.387328	860	5.698907468	772	5.426625016	732	6.5211297	874	6.638874022	893	0.911628409	-0.282772097	normal	0.977386307	0.001866806	normal	0.954729023	0.201400762	normal	0.943862623	-0.023639572	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K11665|0|hsa:54617|INO80, INO80A, INOC1, hINO80; INO80 complex subunit (EC:3.6.4.12); K11665 DNA helicase INO80 [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	SNF2 family N-terminal domain;; DNA-binding domain;; Helicase conserved C-terminal domain	DNA helicase INO80 GN=INO80 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA helicase INO80 [Mustela putorius furo] 
ENSG00000128915(ICE2)	--	18.77744645	1519	17.22527318	1573	15.93761414	1528	18.41636228	1631	16.93918977	1546	17.07302461	1590	0.982943644	0.071732623	normal	0.983421733	-0.04635995	normal	0.983743836	0.049043195	normal	0.937734595	0.023876882	normal	--	--	Cellular Component: transcription elongation factor complex (GO:0008023);; 	--	--	--	--	NMDA receptor-regulated gene protein 2 C-terminus	Little elongation complex subunit 2 GN=ICE2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: NMDA receptor-regulated protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000128917(DLL4)	--	0.0621243	4	0.121674	8	0.0447883	2	0.124394	8	0.0452747	2	0.538916	35	--	--	--	--	--	--	2.93E-05	3.371565185	up	--	--	--	--	--	Biological Process: cell communication (GO:0007154);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06051|0|hsa:54567|DLL4, hdelta2; delta-like 4 (Drosophila); K06051 delta (A)"	Notch signaling pathway (ko04330)	[T]	Signal transduction mechanisms	EGF-like domain;; N terminus of Notch ligand;; Human growth factor-like EGF;; Delta serrate ligand;; EGF-like domain	Delta-like protein 4 (Precursor) GN=DLL4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: delta-like protein 4 [Galeopterus variegatus]
ENSG00000128918(ALDH1A2)	--	0.196761	1	0	0	0	0	0	0	0	0	0.0422213	1	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07249|0|ptr:746847|ALDH1A2; aldehyde dehydrogenase 1 family, member A2; K07249 retinal dehydrogenase [EC:1.2.1.36] (A)"	Retinol metabolism (ko00830)	[C]	Energy production and conversion	Aldehyde dehydrogenase family	Retinal dehydrogenase 2 GN=ALDH1A2 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	retinal dehydrogenase 2 [Canis lupus familiaris] 
ENSG00000128923(MINDY2)	--	4.2599064	616	5.2725935	773	5.591786272	812	4.358056582	638	3.065650209	455	5.30452844	789	0.973975808	0.019745418	normal	0.001871305	-0.784004582	normal	0.976039584	-0.049652054	normal	0.548151801	-0.246305077	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Molecular Function: Lys48-specific deubiquitinase activity (GO:1990380);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF544)	Protein FAM63B GN=FAM63B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM63B [Pteropus alecto] 
ENSG00000128928(IVD)	--	6.0960451	417	6.011407772	399	6.664974189	422	8.214616771	605	10.59967246	667	7.137799183	510	0.376866652	0.504504423	normal	0.011308679	0.717745698	normal	0.918859989	0.264100687	normal	0.007178905	0.503974338	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00253|0|ptr:453333|IVD; isovaleryl-CoA dehydrogenase; K00253 isovaleryl-CoA dehydrogenase [EC:1.3.8.4] (A)	"Valine, leucine and isoleucine degradation (ko00280)"	[EI]	Amino acid transport and metabolism;; Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	"Isovaleryl-CoA dehydrogenase, mitochondrial (Precursor) GN=IVD OS=Homo sapiens (Human) PE=1 SV=1"	EI	Amino acid transport and metabolism;; Lipid transport and metabolism	"PREDICTED: isovaleryl-CoA dehydrogenase, mitochondrial [Oryctolagus cuniculus]"
ENSG00000128944(KNSTRN)	--	18.07753939	546	16.33057093	491	18.12823015	544	18.235173	556	18.21236838	548	14.6994165	447	0.972725569	-0.004635406	normal	0.962077205	0.136627843	normal	0.899896351	-0.290730153	normal	0.886063264	-0.04931431	normal	--	--	--	--	--	--	--	--	Small kinetochore-associated protein {ECO:0000303|PubMed:19667759} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: small kinetochore-associated protein [Loxodonta africana]
ENSG00000128951(DUT)	--	76.56544353	1422	73.03387912	1479	71.93385412	1437	68.69922879	1322	64.95684134	1236	57.95948532	1173	0.976105293	-0.135879234	normal	0.929373479	-0.280056137	normal	0.91007765	-0.300797483	normal	0.1774249	-0.239047966	normal	[F]	Nucleotide transport and metabolism	--	"K01520|0|hsa:1854|DUT, dUTPase; deoxyuridine triphosphatase (EC:3.6.1.23); K01520 dUTP pyrophosphatase [EC:3.6.1.23] (A)"	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	dUTPase	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (Precursor) GN=DUT OS=Homo sapiens (Human) PE=1 SV=4"	F	Nucleotide transport and metabolism	"PREDICTED: deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial [Vicugna pacos]"
ENSG00000128965(CHAC1)	--	9.480004141	255	11.2821587	303	7.1372367	196	2.61453045	73	1.83081526	53	14.78085561	379	3.11E-12	-1.813567596	down	0	-2.502923199	down	0.000351979	0.937757407	normal	0.670485432	-0.595062537	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: gamma-glutamylcyclotransferase activity (GO:0003839);; Biological Process: glutathione catabolic process (GO:0006751);; 	"K07232|3.3256e-168|ptr:467659|CHAC1; ChaC, cation transport regulator homolog 1 (E. coli); K07232 cation transport protein ChaC (A)"	--	[P]	Inorganic ion transport and metabolism	ChaC-like protein	Glutathione-specific gamma-glutamylcyclotransferase 1 {ECO:0000305|PubMed:23070364} OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: cation transport regulator-like protein 1 [Equus przewalskii]
ENSG00000128973(CLN6)	--	58.90280404	1979	69.12339361	2422	65.86795902	2168	58.78579391	2003	48.57407902	1662	54.89922359	1886	0.98678914	-0.01343109	normal	0.141440794	-0.564277007	normal	0.969554937	-0.209169952	normal	0.117485736	-0.264448883	normal	--	--	--	"K12359|2.7296e-179|hsa:54982|CLN6, CLN4A, HsT18960, nclf; ceroid-lipofuscinosis, neuronal 6, late infantile, variant; K12359 ceroid-lipofuscinosis neuronal protein 6 (A)"	--	--	--	Ceroid-lipofuscinosis neuronal protein 6	Ceroid-lipofuscinosis neuronal protein 6 GN=CLN6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ceroid-lipofuscinosis neuronal protein 6 homolog [Chrysochloris asiatica]
ENSG00000128989(ARPP19)	--	73.91802317	4789	80.619156	5144	73.17146663	4578	88.934145	6009	83.53539786	5330	86.856124	5647	0.962307644	0.296483159	normal	0.99332511	0.029809723	normal	0.961691342	0.294388014	normal	0.274230327	0.205616359	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	cAMP-regulated phosphoprotein/endosulfine conserved region	cAMP-regulated phosphoprotein 19 GN=ARPP19 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: cAMP-regulated phosphoprotein 19 isoform X1 [Equus caballus] 
ENSG00000129003(VPS13C)	--	14.39954223	3583	17.2196758	4256	15.47655923	3761	15.0527077	3760	12.91038153	3201	19.05083313	4736	0.991370457	0.038716148	normal	0.73603985	-0.432224281	normal	0.93749544	0.324144939	normal	0.985895646	-0.008649623	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Protein of unknown function (DUF1162);; N-terminal region of Chorein, a TM vesicle-mediated sorter;; ATG C terminal domain"	Vacuolar protein sorting-associated protein 13C OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 13C isoform 1 [Odobenus rosmarus divergens]
ENSG00000129009(ISLR)	--	1.007705599	27	0.535892106	18	1.76767082	28	0.289781129	10	1.477157577	32	0.430739733	16	0.720759353	-1.334554659	normal	0.93555297	0.760194519	normal	0.951124767	-0.760669194	normal	0.715986195	-0.351109252	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Immunoglobulin I-set domain;; Leucine Rich Repeat;; Leucine Rich repeat;; Immunoglobulin domain	Immunoglobulin superfamily containing leucine-rich repeat protein (Precursor) GN=ISLR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily containing leucine-rich repeat protein isoform X1 [Equus caballus] 
ENSG00000129028(THAP10)	--	5.0063	183	6.08993	222	6.56423	240	6.370177	227	6.22503	182	5.93045	219	0.923030616	0.277918162	normal	0.907681731	-0.305743265	normal	0.958581597	-0.139474593	normal	0.900255264	-0.059659342	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 10 GN=THAP10 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: THAP domain-containing protein 10 [Galeopterus variegatus]
ENSG00000129038(LOXL1)	--	0.129008	5	0.0252398	1	0.0485756	1	0.152559	6	0.172463	6	0.0251762	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (GO:0016641);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K14678|0|hsa:4016|LOXL1, LOL, LOXL; lysyl oxidase-like 1; K14678 lysyl oxidase-like protein 1 [EC:1.4.3.-] (A)"	--	--	--	Lysyl oxidase	Lysyl oxidase homolog 1 (Precursor) GN=LOXL1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: lysyl oxidase homolog 1 [Equus caballus]
ENSG00000129048(ACKR4)	--	0.13489	4	0.304764	9	0.237205	6	0.0670656	2	0.196396	5	0.100346	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04186|0|hsa:51554|ACKR4, CC-CKR-11, CCBP2, CCR-11, CCR10, CCR11, CCRL1, CCX_CKR, CCX-CKR, CKR-11, PPR1, VSHK1; atypical chemokine receptor 4; K04186 C-C chemokine receptor-like 1 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Atypical chemokine receptor 4 GN=ACKR4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: atypical chemokine receptor 4 [Galeopterus variegatus]
ENSG00000129055(ANAPC13)	--	29.916305	659	25.366194	557	26.851197	577	30.445522	645	31.692899	687	31.978214	679	0.972935731	-0.061666237	normal	0.910050348	0.28051936	normal	0.941250923	0.226002217	normal	0.555432618	0.144469552	normal	--	--	--	K12456|8.33465e-47|phd:102337957|ANAPC13; anaphase promoting complex subunit 13; K12456 anaphase-promoting complex subunit 13 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914)	--	--	Apc13p protein	Anaphase-promoting complex subunit 13 GN=ANAPC13 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anaphase-promoting complex subunit 13 isoform X1 [Pantholops hodgsonii]
ENSG00000129071(MBD4)	--	9.773954	498	8.96375856	450	9.062772085	442	11.176739	558	11.408206	588	10.704803	555	0.963441231	0.132899638	normal	0.811470999	0.36339344	normal	0.872313135	0.319173426	normal	0.216671213	0.27002332	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	"K10801|0|hsa:8930|MBD4, MED1; methyl-CpG binding domain protein 4; K10801 methyl-CpG-binding domain protein 4 [EC:3.2.2.-] (A)"	Base excision repair (ko03410)	[KB]	Transcription;; Chromatin structure and dynamics	Methyl-CpG binding domain;; HhH-GPD superfamily base excision DNA repair protein	Methyl-CpG-binding domain protein 4 GN=MBD4 OS=Homo sapiens (Human) PE=1 SV=1	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: methyl-CpG-binding domain protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000129083(COPB1)	--	60.58113233	3778	61.19305013	3791	57.66012829	3530	72.5306	4429	70.36540845	4371	66.59438487	4144	0.982776792	0.198451436	normal	0.984397	0.183890003	normal	0.977666882	0.222976125	normal	0.279267069	0.200353312	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: COPI vesicle coat (GO:0030126);; 	"K17301|0|hsa:1315|COPB1, COPB; coatomer protein complex, subunit beta 1; K17301 coatomer, subunit beta (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptin N terminal region;; Coatomer beta subunit appendage platform;; Coatomer beta C-terminal region;; HEAT repeats;; HEAT repeat;; HEAT-like repeat;; Dos2-interacting transcription regulator of RNA-Pol-II;; Armadillo/beta-catenin-like repeat	Coatomer subunit beta GN=COPB1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit beta [Tupaia chinensis]
ENSG00000129084(PSMA1)	--	81.5990647	1857	76.846034	1715	79.27518454	1777	96.79677299	2216	87.17510075	1972	79.965127	1822	0.965571344	0.223981994	normal	0.973835266	0.179876407	normal	0.985684361	0.0277645	normal	0.465849743	0.146306157	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: endopeptidase activity (GO:0004175);; Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Cellular Component: proteasome core complex, alpha-subunit complex (GO:0019773);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; "	"K02725|0|bom:102282779|PSMA1; proteasome (prosome, macropain) subunit, alpha type, 1; K02725 20S proteasome subunit alpha 6 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome subunit A N-terminal signature	Proteasome subunit alpha type-1 GN=PSMA1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit alpha type-1 isoform X1 [Bos mutus]
ENSG00000129103(SUMF2)	--	175.747851	7932	167.8048466	7661	177.314739	8131	210.595291	9731	200.7193525	9051	181.228666	8099	0.982108211	0.264024893	normal	0.988008591	0.219078094	normal	0.995520592	-0.013977845	normal	0.462672814	0.158588785	normal	[S]	Function unknown	--	--	--	--	--	Sulfatase-modifying factor enzyme 1	Sulfatase-modifying factor 2 (Precursor) GN=SUMF2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sulfatase-modifying factor 2 [Eptesicus fuscus]
ENSG00000129116(PALLD)	--	40.12171746	2892	46.99580892	3584	45.72362321	3550	55.80556153	4430	49.02131956	3843	43.13197689	3590	0.097976707	0.584154424	normal	0.990300082	0.079203503	normal	0.991421231	0.007870043	normal	0.232699601	0.220991561	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein E;; Natural killer cell receptor 2B4	Palladin GN=PALLD OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: palladin isoform X3 [Felis catus]
ENSG00000129128(SPCS3)	--	25.20411	1584	26.79436	1669	27.40647	1658	32.56772	2064	26.87132	1689	26.45877	1659	0.862272138	0.350739611	normal	0.984822555	-0.004237368	normal	0.985083538	-0.007414802	normal	0.578014559	0.11825024	normal	--	--	Cellular Component: signal peptidase complex (GO:0005787);; Biological Process: signal peptide processing (GO:0006465);; Molecular Function: peptidase activity (GO:0008233);; Cellular Component: integral component of membrane (GO:0016021);; 	K12948|1.00815e-128|ssc:100526140|SPCS3; signal peptidase complex subunit 3 homolog (S. cerevisiae); K12948 signal peptidase complex subunit 3 [EC:3.4.-.-] (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Signal peptidase subunit	Signal peptidase complex subunit 3 GN=SPCS3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal peptidase complex subunit 3 [Erinaceus europaeus] 
ENSG00000129158(SERGEF)	--	15.98596519	371	12.35726278	268	14.89815485	313	11.04495721	225	10.7521922	212	10.47604485	234	0.017177523	-0.748302446	normal	0.857462719	-0.357322512	normal	0.737533586	-0.425558935	normal	0.027855539	-0.525717901	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	--	"K15421|0|hsa:26297|SERGEF, DELGEF, Gnefr; secretion regulating guanine nucleotide exchange factor; K15421 secretion-regulating guanine nucleotide exchange factor (A)"	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat	Secretion-regulating guanine nucleotide exchange factor GN=SERGEF OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: secretion-regulating guanine nucleotide exchange factor [Felis catus]
ENSG00000129159(KCNC1)	--	0.0808629	5	0.4593526	21	1.9652078	24	0.07620023	5	0.1058245	4	0.1131247	7	--	--	--	0.332327723	-2.047759675	normal	0.602644209	-1.590882693	normal	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04887|0|mcc:696106|KCNC1; potassium voltage-gated channel, Shaw-related subfamily, member 1; K04887 potassium voltage-gated channel Shaw-related subfamily C member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily C member 1 GN=KCNC1 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily C member 1 [Orcinus orca]
ENSG00000129167(TPH1)	--	0.054183958	4	0.074201012	6	0.518045727	9	0.06089127	5	0.052428851	3	0.026843046	2	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen (GO:0016714);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00502|0|hsa:7166|TPH1, TPRH, TRPH, TPH; tryptophan hydroxylase 1 (EC:1.14.16.4); K00502 tryptophan 5-monooxygenase [EC:1.14.16.4] (A)"	Tryptophan metabolism (ko00380);; Serotonergic synapse (ko04726)	[E]	Amino acid transport and metabolism	Biopterin-dependent aromatic amino acid hydroxylase;; ACT domain	Tryptophan 5-hydroxylase 1 GN=TPH1 OS=Homo sapiens (Human) PE=1 SV=4	E	Amino acid transport and metabolism	PREDICTED: tryptophan 5-hydroxylase 1 [Ursus maritimus]
ENSG00000129173(E2F8)	--	3.45258866	241	4.062569	283	3.835386	265	2.112207974	147	2.590649278	181	1.9908597	141	0.065619584	-0.737959616	normal	0.13687934	-0.661778205	normal	0.002761541	-0.911339655	normal	0.002026279	-0.771634528	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09391|0|hsa:79733|E2F8, E2F-8; E2F transcription factor 8; K09391 transcription factor E2F7/8 (A)"	--	--	--	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F8 GN=E2F8 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor E2F8 [Loxodonta africana] 
ENSG00000129187(DCTD)	--	41.15936755	1189	41.33340894	1100	39.5261393	1109	53.89863935	1547	50.86309856	1462	54.25825513	1577	0.850811082	0.348496469	normal	0.771859952	0.38854849	normal	0.337272773	0.49905831	normal	0.007643411	0.411353743	normal	[F]	Nucleotide transport and metabolism	Biological Process: tRNA wobble adenosine to inosine editing (GO:0002100);; Molecular Function: tRNA-specific adenosine deaminase activity (GO:0008251);; 	K01493|8.57074e-140|hsa:1635|DCTD; dCMP deaminase (EC:3.5.4.12); K01493 dCMP deaminase [EC:3.5.4.12] (A)	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Cytidine and deoxycytidylate deaminase zinc-binding region	Deoxycytidylate deaminase GN=DCTD OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: deoxycytidylate deaminase-like [Chrysochloris asiatica]
ENSG00000129194(SOX15)	--	1.149485	22	2.365517	41	1.27342	23	1.2758247	25	1.469046	28	1.426086	28	0.986984625	0.144145161	normal	0.949814801	-0.547060649	normal	0.983657676	0.259987386	normal	0.927934945	-0.10790181	normal	--	--	--	"K09271|8.3351e-144|hsa:6665|SOX15, SOX20, SOX26, SOX27; SRY (sex determining region Y)-box 15; K09271 transcription factor SOX, other (A)"	--	[K]	Transcription	HMG (high mobility group) box;; HMG-box domain	Protein SOX-15 GN=SOX15 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein SOX-15 [Galeopterus variegatus]
ENSG00000129195(FAM64A)	--	24.8700009	807	23.571625	739	22.51244869	762	21.25501172	687	20.27232	635	19.49793	637	0.92473022	-0.262548343	normal	0.936258669	-0.239714535	normal	0.921556016	-0.266210403	normal	0.193743278	-0.257971994	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1466)	Protein FAM64A GN=FAM64A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"Protein FAM64A, partial [Bos mutus]"
ENSG00000129197(RPAIN)	--	25.762007	577	29.037521	657	28.5587075	623	24.390845	540	23.293857	498	26.370942	572	0.965081139	-0.126096991	normal	0.676348051	-0.420059712	normal	0.965290942	-0.131176032	normal	0.304373863	-0.226979076	normal	--	--	--	--	--	--	--	Replication protein A interacting N-terminal;; Replication protein A interacting C-terminal;; Replication protein A interacting middle	RPA-interacting protein GN=RPAIN OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RPA-interacting protein isoform X3 [Equus caballus]
ENSG00000129204(USP6)	--	0.883645285	143	0.905378017	147	0.91904785	148	0.83403675	134	0.841330614	135	0.914854055	148	0.963626232	-0.123246092	normal	0.960129545	-0.142750272	normal	0.967885579	-0.008207576	normal	0.865273703	-0.091750793	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11837|0|hsa:9098|USP6, HRP1, TRE17, TRE2, TRESMCR, Tre-2, USP6-short; ubiquitin specific peptidase 6 (EC:3.4.19.12); K11837 ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Rab-GTPase-TBC domain;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 6 GN=USP6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 32 [Tupaia chinensis]
ENSG00000129214(SHBG)	--	0.419821334	4	0.6882225	7	0.933485821	14	0.199899001	3	0.099241399	1	0.541369996	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Laminin G domain;; Laminin G domain	Sex hormone-binding globulin (Precursor) GN=SHBG OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: sex hormone-binding globulin isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000129219(PLD2)	--	10.84563637	741	8.442600863	574	9.018140349	650	7.469532074	528	7.737926257	544	5.773192489	410	0.293395784	-0.518487467	normal	0.967732796	-0.098603745	normal	0.02590602	-0.671123461	normal	0.03777782	-0.428789862	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K01115|0|ggo:101135996|PLD2; phospholipase D2 isoform 1; K01115 phospholipase D1/2 [EC:3.1.4.4] (A)	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; Sphingolipid signaling pathway (ko04071);; Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666);; Glutamatergic synapse (ko04724);; GnRH signaling pathway (ko04912);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	PX domain;; Phospholipase D Active site motif;; PLD-like domain	Phospholipase D2 GN=PLD2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: phospholipase D2 isoform X1 [Camelus ferus]
ENSG00000129226(CD68)	--	23.2760037	856	19.343489	689	23.182067	865	57.86254	2109	46.023597	1650	56.98140346	2119	7.16E-12	1.268546395	up	1.24E-10	1.236655423	up	3.55E-12	1.282839479	up	2.04E-11	1.265255091	up	--	--	Cellular Component: membrane (GO:0016020);; 	K06501|1.55773e-141|ggo:101131454|CD68; macrosialin isoform 1; K06501 CD68 antigen (A)	Lysosome (ko04142)	[R]	General function prediction only	Lysosome-associated membrane glycoprotein (Lamp)	Macrosialin (Precursor) GN=CD68 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: macrosialin [Galeopterus variegatus]
ENSG00000129235(TXNDC17)	--	46.818811	783	50.2525566	860	62.3837481	848	64.022614	1063	50.120757	799	49.8577265	795	0.688776097	0.409533129	normal	0.969581034	-0.127335339	normal	0.972936023	-0.101214388	normal	0.813353695	0.070928298	normal	--	--	--	--	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF953)	Thioredoxin domain-containing protein 17 GN=TXNDC17 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: thioredoxin domain-containing protein 17 [Ceratotherium simum simum]
ENSG00000129244(ATP1B2)	--	0.036985827	2	0	0	0.02261719	0	0.091700198	4	0.13187907	5	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: sodium:potassium-exchanging ATPase complex (GO:0005890);; Biological Process: potassium ion transport (GO:0006813);; Biological Process: sodium ion transport (GO:0006814);; 	"K01540|0|ptr:749043|ATP1B2; ATPase, Na+/K+ transporting, beta 2 polypeptide; K01540 sodium/potassium-transporting ATPase subunit beta (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Insulin secretion (ko04911);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Proximal tubule bicarbonate reclamation (ko04964);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Carbohydrate digestion and absorption (ko04973);; Protein digestion and absorption (ko04974);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Sodium / potassium ATPase beta chain	Sodium/potassium-transporting ATPase subunit beta-2 GN=ATP1B2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium-transporting ATPase subunit beta-2 [Sus scrofa]
ENSG00000129245(FXR2)	--	24.62491538	1519	25.0031	1575	26.4524006	1665	24.19262502	1488	26.148398	1600	21.82620711	1350	0.982922489	-0.060517757	normal	0.984252442	0.001292288	normal	0.905930986	-0.310540367	normal	0.568669821	-0.122031797	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K15516|0|mcf:101867240|uncharacterized LOC101867240; K15516 fragile X mental retardation protein (A)	RNA transport (ko03013)	--	--	Fragile X-related 1 protein C terminal;; KH domain;; Agenet domain;; KH domain	Fragile X mental retardation syndrome-related protein 2 GN=FXR2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: fragile X mental retardation syndrome-related protein 2 [Mustela putorius furo]
ENSG00000129250(KIF1C)	--	40.00636082	5846	40.23752678	6191	44.9881842	6705	50.9534091	7544	41.5745146	6112	41.13799254	5844	0.946061794	0.336969448	normal	0.994041367	-0.039944653	normal	0.986624357	-0.20652266	normal	0.900709545	0.035355769	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10392|0|hsa:10749|KIF1C, LTXS1, SATX2, SAX2, SPAX2, SPG58; kinesin family member 1C; K10392 kinesin family member 1 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain;; FHA domain	Kinesin-like protein KIF1C GN=KIF1C OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF1C [Orcinus orca]
ENSG00000129255(MPDU1)	--	65.788468	1150	68.978409	1233	76.742734	1215	64.94195502	1220	64.542553	1162	69.778934	1341	0.98044374	0.054344529	normal	0.976908705	-0.106854259	normal	0.975396923	0.133902782	normal	0.924234057	0.028356776	normal	--	--	--	K09660|8.93492e-141|ggo:101130370|MPDU1; mannose-P-dolichol utilization defect 1 protein; K09660 mannose-P-dolichol utilization defect 1 (A)	--	[R]	General function prediction only	PQ loop repeat	Mannose-P-dolichol utilization defect 1 protein GN=MPDU1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	Mannose-P-dolichol utilization defect 1 protein [Tupaia chinensis]
ENSG00000129292(PHF20L1)	--	14.11779017	1308	14.68859235	1465	14.23836456	1278	14.95417746	1467	15.38974441	1471	15.68287183	1537	0.97640251	0.134524807	normal	0.98335629	-0.015513994	normal	0.943147556	0.257659497	normal	0.569524012	0.122389878	normal	[R]	General function prediction only	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K18402|0|ggo:101147021|PHF20L1; PHD finger protein 20-like protein 1 isoform 1; K18402 PHD finger protein 20 (A)	--	--	--	Protein of unknown function (DUF3776);; PHD-finger	PHD finger protein 20-like protein 1 GN=PHF20L1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: PHD finger protein 20-like 1 isoformX2 [Canis lupus familiaris] 
ENSG00000129295(LRRC6)	--	1.953113439	80	1.561177201	63	2.62306705	112	1.7294224	79	2.10187609	96	2.508755234	95	0.973092629	-0.048050932	normal	0.797906918	0.575000766	normal	0.953660636	-0.242235186	normal	0.937734595	0.062765396	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine-rich repeat;; Leucine rich repeat	Protein tilB homolog GN=LRRC6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein tilB homolog [Oryctolagus cuniculus]
ENSG00000129315(CCNT1)	--	11.9738806	1194	11.43550697	1258	19.2505514	1297	14.98713649	1331	14.94580861	1390	13.9559409	1427	0.976098709	0.1257222	normal	0.976767216	0.122386399	normal	0.976813338	0.129371555	normal	0.563343191	0.125032522	normal	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	--	"K15188|0|hsa:904|CCNT1, CCNT, CYCT1, HIVE1; cyclin T1; K15188 cyclin T (A)"	Transcriptional misregulation in cancer (ko05202)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-T1 GN=CCNT1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-T1 isoform X1 [Ursus maritimus]
ENSG00000129317(PUS7L)	--	5.064050834	640	5.816659788	602	4.617970056	554	6.014031058	841	4.800445162	712	5.05826218	645	0.805914753	0.362440618	normal	0.94391874	0.220178123	normal	0.946573597	0.210588508	normal	0.176210516	0.269193813	normal	[S]	Function unknown	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	K06176|0|hsa:83448|PUS7L; pseudouridylate synthase 7 homolog (S. cerevisiae)-like (EC:5.4.99.-); K06176 tRNA pseudouridine13 synthase [EC:5.4.99.27] (A)	--	[S]	Function unknown	tRNA pseudouridine synthase D (TruD)	Pseudouridylate synthase 7 homolog-like protein GN=PUS7L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pseudouridylate synthase 7 homolog-like protein [Galeopterus variegatus]
ENSG00000129347(KRI1)	--	6.982958708	590	7.539430018	514	8.197688389	631	6.544400709	557	6.657646467	559	4.75255	403	0.96700836	-0.113565447	normal	0.967172474	0.099372958	normal	0.038457445	-0.65317601	normal	0.399865595	-0.213578224	normal	--	--	--	K14786|0|hsa:65095|KRI1; KRI1 homolog (S. cerevisiae); K14786 protein KRI1 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	KRI1-like family C-terminal;; KRI1-like family	Protein KRI1 homolog GN=KRI1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: protein KRI1 homolog [Bos mutus]
ENSG00000129351(ILF3)	--	78.884114	6827	82.21896003	7271	81.707992	7077	91.085973	7685	90.71804415	7761	80.626715	6925	0.992666219	0.139931552	normal	0.994527527	0.072647575	normal	0.994800579	-0.039606734	normal	0.830751125	0.057796101	normal	--	--	--	"K13090|0|pps:100974824|ILF3; interleukin enhancer binding factor 3, 90kDa; K13090 interleukin enhancer-binding factor 3 (A)"	--	[R]	General function prediction only	DZF domain;; Double-stranded RNA binding motif;; double strand RNA binding domain from DEAD END PROTEIN 1	Interleukin enhancer-binding factor 3 GN=ILF3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: interleukin enhancer-binding factor 3 isoform X1 [Orycteropus afer afer]
ENSG00000129353(SLC44A2)	--	12.70838177	701	8.205522125	476	9.900139462	567	11.351555	643	15.1403835	829	8.799036783	501	0.962651836	-0.155072926	normal	0.002057917	0.777090531	normal	0.952734677	-0.186300595	normal	0.764420377	0.156356075	normal	--	--	--	"K15377|0|ptr:455711|SLC44A2; solute carrier family 44 (choline transporter), member 2; K15377 solute carrier family 44 (choline transporter-like protein), member 2/4/5 (A)"	Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Plasma-membrane choline transporter	Choline transporter-like protein 2 GN=SLC44A2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: choline transporter-like protein 2 isoform X1 [Tupaia chinensis]
ENSG00000129354(AP1M2)	--	10.92840891	175	20.04185032	253	16.29542965	268	26.59381128	389	19.8285706	237	40.01437067	508	4.70E-06	1.11485354	up	0.960283879	-0.114966692	normal	0.000210781	0.910510012	normal	0.24140204	0.684106173	normal	--	--	--	"K12393|0|hsa:10053|AP1M2, AP1-mu2, HSMU1B, MU-1B, MU1B, mu2; adaptor-related protein complex 1, mu 2 subunit; K12393 AP-1 complex subunit mu (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family;; Clathrin adaptor complex small chain	AP-1 complex subunit mu-2 GN=AP1M2 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-1 complex subunit mu-2 isoform X1 [Ursus maritimus]
ENSG00000129355(CDKN2D)	--	3.9677	78	2.75828	58	3.03183	65	3.82913	72	2.970631	53	4.059269	76	0.970580283	-0.143368973	normal	0.973612996	-0.147463229	normal	0.966665143	0.21268784	normal	0.987212077	-0.021175624	normal	[R]	General function prediction only	--	"K06623|5.70073e-113|ptr:745942|CDKN2D; cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); K06623 cyclin-dependent kinase inhibitor 2D (A)"	FoxO signaling pathway (ko04068);; Cell cycle (ko04110)	[R]	General function prediction only	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Cyclin-dependent kinase 4 inhibitor D GN=CDKN2D OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-dependent kinase 4 inhibitor D [Orycteropus afer afer]
ENSG00000129422(MTUS1)	--	34.10989008	4095	38.8045968	4675	33.21027553	4045	47.96813823	5792	72.1919819	9004	116.309897	14143	0.605495999	0.469217209	normal	6.85E-06	0.923954075	normal	0	1.797202101	up	0.10247278	1.156419271	normal	--	--	--	--	--	--	--	--	Microtubule-associated tumor suppressor 1 GN=MTUS1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: microtubule-associated tumor suppressor 1 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000129437(KLK14)	--	0.066288952	1	0	0	0.230776692	3	0.11840234	2	0	0	0.129887936	2	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09622|0|hsa:43847|KLK14, KLK-L6; kallikrein-related peptidase 14; K09622 kallikrein 14 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin	Kallikrein-14 (Precursor) GN=KLK14 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: kallikrein-14 [Ceratotherium simum simum]
ENSG00000129450(SIGLEC9)	--	0	0	0	0	0	0	0	0	0	0	0.036624899	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06740|0|hsa:27180|SIGLEC9, CD329, CDw329, FOAP-9, OBBP-LIKE, siglec-9; sialic acid binding Ig-like lectin 9; K06740 sialic acid binding Ig-like lectin 9 (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; CD80-like C2-set immunoglobulin domain	Sialic acid-binding Ig-like lectin 9 (Precursor) GN=SIGLEC9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: sialic acid-binding Ig-like lectin 8 isoform X2 [Galeopterus variegatus]
ENSG00000129451(KLK10)	--	0.086514996	2	0.385107343	9	0.208535177	4	0	0	0.041862036	0	0.085232747	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09619|0|hsa:5655|KLK10, NES1, PRSSL1; kallikrein-related peptidase 10 (EC:3.4.21.35); K09619 kallikrein 10 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin	Kallikrein-10 (Precursor) GN=KLK10 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: kallikrein-10-like [Ceratotherium simum simum] 
ENSG00000129455(KLK8)	--	0	0	0	0	0	0	0.0401757	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	K08650|0|pon:100437370|KLK8; kallikrein-related peptidase 8; K08650 kallikrein 8 (neuropsin/ovasin) [EC:3.4.21.118] (A)	--	[E]	Amino acid transport and metabolism	Trypsin	Kallikrein-8 (Precursor) GN=KLK8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: kallikrein-8 [Ursus maritimus]
ENSG00000129460(NGDN)	--	23.24600199	503	25.62362712	572	23.85055073	518	26.51512813	581	27.83408216	596	24.60738652	538	0.955190895	0.176645154	normal	0.972118191	0.037772791	normal	0.971451389	0.046230192	normal	0.772299949	0.084986681	normal	--	--	--	"K14765|2.46977e-155|ptr:452802|NGDN; neuroguidin, EIF4E binding protein; K14765 U3 small nucleolar ribonucleoprotein protein LCP5 (A)"	--	[A]	RNA processing and modification	Sas10/Utp3/C1D family	Neuroguidin GN=NGDN OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: neuroguidin [Galeopterus variegatus]
ENSG00000129472(RAB2B)	--	10.5881	474	10.3355	464	9.73651	433	8.86755	400	9.55548	427	10.737	485	0.911546881	-0.274748423	normal	0.959805708	-0.140836621	normal	0.958429969	0.15481514	normal	0.790226436	-0.08420568	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07878|1.59187e-160|tup:102468127|RAB2B; RAB2B, member RAS oncogene family; K07878 Ras-related protein Rab-2B (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase	Ras-related protein Rab-2B GN=RAB2B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-2B isoform 1 [Ceratotherium simum simum]
ENSG00000129480(DTD2)	--	26.62338536	2055	31.84645082	2503	30.69911331	2247	24.89291282	1642	23.68931807	1626	24.72184104	2032	0.857117403	-0.354219519	normal	0.026170608	-0.643271388	normal	0.980157517	-0.15328263	normal	0.028153043	-0.38123912	normal	--	--	Molecular Function: aminoacyl-tRNA editing activity (GO:0002161);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: D-aminoacyl-tRNA deacylase activity (GO:0051499);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	D-Tyr-tRNA(Tyr) deacylase	Probable D-tyrosyl-tRNA(Tyr) deacylase 2 GN=DTD2 OS=Homo sapiens (Human) PE=2 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: probable D-tyrosyl-tRNA(Tyr) deacylase 2 isoform X2 [Oryctolagus cuniculus]
ENSG00000129484(PARP2)	--	15.517914	599	14.98760268	572	17.19305774	654	15.75181	612	13.553563	505	13.25583113	509	0.973755946	0.000143023	normal	0.948022005	-0.20059345	normal	0.794935156	-0.368946734	normal	0.4226779	-0.188174694	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; Biological Process: protein ADP-ribosylation (GO:0006471);; 	K10798|0|ptr:465197|PARP2; poly (ADP-ribose) polymerase 2; K10798 poly [ADP-ribose] polymerase [EC:2.4.2.30] (A)	Base excision repair (ko03410)	[KLO]	"Transcription;; Replication, recombination and repair;; Posttranslational modification, protein turnover, chaperones"	"Poly(ADP-ribose) polymerase catalytic domain;; Poly(ADP-ribose) polymerase, regulatory domain;; WGR domain"	Poly [ADP-ribose] polymerase 2 GN=PARP2 OS=Homo sapiens (Human) PE=1 SV=2	KLO	"Transcription;; Replication, recombination and repair;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: poly [ADP-ribose] polymerase 2 isoform 1 [Ceratotherium simum simum]
ENSG00000129514(FOXA1)	--	2.301617	111	2.432605	116	2.53817	123	8.93672	435	9.50164	470	7.43368	370	0	1.925141958	up	0	1.983229403	up	2.02E-11	1.568897584	up	5.90E-19	1.843634266	up	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transcription factor binding (GO:0008134);; Molecular Function: protein domain specific binding (GO:0019904);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09387|0|hsa:3169|FOXA1, HNF3A, TCF3A; forkhead box A1; K09387 forkhead box protein A1, hepatocyte nuclear factor 3-alpha (A)"	--	[K]	Transcription	Fork head domain;; Forkhead N-terminal region;; HNF3 C-terminal domain	Hepatocyte nuclear factor 3-alpha GN=FOXA1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: hepatocyte nuclear factor 3-alpha [Leptonychotes weddellii]
ENSG00000129515(SNX6)	--	66.87875	2853	53.53113258	2179	66.97445425	2784	75.361286	3253	76.0288	3229	57.12908364	2477	0.983992526	0.158378898	normal	0.212094735	0.545681729	normal	0.979902191	-0.176754931	normal	0.536016591	0.175227577	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K17920|0|hsa:58533|SNX6, MSTP010, TFAF2; sorting nexin 6; K17920 sorting nexin-5/6/32 (A)"	--	[V]	Defense mechanisms	PX domain;; Vps5 C terminal like;; BAR domain	"Sorting nexin-6, N-terminally processed GN=SNX6 OS=Homo sapiens (Human) PE=1 SV=1"	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-6 isoform 1 [Dasypus novemcinctus]
ENSG00000129518(EAPP)	--	14.92609	385	13.78255093	367	14.53481	371	17.82894912	463	17.37605	445	15.36589003	398	0.933735542	0.23446732	normal	0.923039381	0.255640841	normal	0.965486298	0.092692942	normal	0.461816317	0.196158876	normal	--	--	--	--	--	[S]	Function unknown	E2F-associated phosphoprotein	E2F-associated phosphoprotein GN=EAPP OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: E2F-associated phosphoprotein [Ceratotherium simum simum]
ENSG00000129521(EGLN3)	--	15.017929	617	19.945518	829	13.456612	557	18.56021984	795	11.95716013	501	13.221721	538	0.853240839	0.334117517	normal	0.004126333	-0.746217446	normal	0.971271973	-0.058201799	normal	0.789589588	-0.150284806	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K09592|4.87888e-178|pps:100990967|EGLN3; egl-9 family hypoxia-inducible factor 3; K09592 hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] (A)	HIF-1 signaling pathway (ko04066);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily	Egl nine homolog 3 GN=EGLN3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: egl nine homolog 3 [Canis lupus familiaris] 
ENSG00000129534(MIS18BP1)	--	13.688982	1261	17.191228	1452	18.81287356	1455	14.856317	1379	15.59513806	1257	14.15253458	1308	0.979251383	0.098107591	normal	0.95503679	-0.229226503	normal	0.972587506	-0.161770625	normal	0.655552492	-0.100980044	normal	--	--	--	--	--	--	--	SANTA (SANT Associated)	Mis18-binding protein 1 GN=MIS18BP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mis18-binding protein 1 [Ceratotherium simum simum]
ENSG00000129535(NRL)	--	0.28844888	9	0.320940001	10	0.361906347	8	0.5561384	17	0.64511174	16	0.825157226	26	--	--	--	--	--	--	0.589184255	1.52480743	normal	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09038|7.48788e-127|ptr:452806|NRL; neural retina leucine zipper; K09038 neural retina-specific leucine zipper protein (A)	--	[K]	Transcription	bZIP Maf transcription factor;; Maf N-terminal region	Neural retina-specific leucine zipper protein GN=NRL OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: neural retina-specific leucine zipper protein [Odobenus rosmarus divergens]
ENSG00000129538(RNASE1)	--	0.098407058	1	0.387377845	4	0.1398431	1	0.367451445	3	0.351481312	3	0.216376475	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K01168|1.05938e-91|hsa:6035|RNASE1, RAC1, RIB1, RNS1; ribonuclease, RNase A family, 1 (pancreatic) (EC:3.1.27.5); K01168 pancreatic ribonuclease [EC:3.1.27.5] (A)"	--	--	--	Pancreatic ribonuclease	Ribonuclease pancreatic (Precursor) GN=RNASE1 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	RNase1 alpha [Murina leucogaster]
ENSG00000129559(NEDD8)	--	170.669233	1955	174.98545	2107	180.09826	2154	205.41403	2474	180.32253	2053	179.85753	2079	0.923218519	0.30862861	normal	0.986003243	-0.058840458	normal	0.986493854	-0.059377498	normal	0.786760395	0.066097992	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K12158|2.10015e-27|pale:102893164|NEDD8; neural precursor cell expressed, developmentally down-regulated 8; K12158 ubiquitin-like protein Nedd8 (A)"	--	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin-like domain	NEDD8 (Precursor) GN=NEDD8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NEDD8 [Pteropus alecto] 
ENSG00000129562(DAD1)	--	189.20105	1471	202.775386	1590	172.0274601	1350	230.6435911	1815	226.2074	1744	245.6443213	1937	0.939243574	0.272083824	normal	0.980738627	0.111845121	normal	0.288738757	0.512091682	normal	0.071704998	0.296022622	normal	--	--	Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity (GO:0004579);; Cellular Component: oligosaccharyltransferase complex (GO:0008250);; Cellular Component: integral component of membrane (GO:0016021);; 	K12668|4.8011e-64|umr:103681026|DAD1; defender against cell death 1; K12668 oligosaccharyltransferase complex subunit epsilon (A)	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	DAD family	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 GN=DAD1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1-like [Trichechus manatus latirostris]
ENSG00000129566(TEP1)	--	3.327738866	704	4.200480602	794	3.78922485	827	2.998704804	637	3.075341388	665	3.987856161	864	0.95842832	-0.174713234	normal	0.915506819	-0.276634626	normal	0.976472206	0.054754576	normal	0.668547181	-0.122324841	normal	[R]	General function prediction only	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	"K11127|0|hsa:7011|TEP1, TLP1, TP1, TROVE1, VAULT2, p240; telomerase-associated protein 1; K11127 telomerase protein component 1 (A)"	--	[R]	General function prediction only	"TROVE domain;; TEP1 N-terminal domain;; WD domain, G-beta repeat;; NACHT domain;; Domain of unknown function (DUF4062);; AAA ATPase domain"	Telomerase protein component 1 GN=TEP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: telomerase protein component 1 [Equus przewalskii] 
ENSG00000129595(EPB41L4A)	--	5.245227328	425	5.895855	437	5.079679265	359	5.201257	395	5.3784139	390	5.50355095	412	0.960602422	-0.135932542	normal	0.949971431	-0.184907912	normal	0.94918103	0.189622877	normal	0.893723959	-0.050034017	normal	--	--	--	--	--	[R]	General function prediction only	FERM central domain;; FERM N-terminal domain;; FERM C-terminal PH-like domain;; FERM adjacent (FA)	Band 4.1-like protein 4A GN=EPB41L4A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: band 4.1-like protein 4A [Vicugna pacos]
ENSG00000129625(REEP5)	--	46.76428835	2302	46.30703124	2295	48.99577576	2305	70.40152302	3464	61.22724068	3066	67.20180446	3239	0.151278807	0.558413113	normal	0.806160037	0.396210398	normal	0.463617823	0.482222137	normal	0.001051013	0.479762757	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K17279|1.51256e-137|ptr:737918|REEP5; receptor accessory protein 5; K17279 receptor expression-enhancing protein 5/6 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"TB2/DP1, HVA22 family"	Receptor expression-enhancing protein 5 GN=REEP5 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: receptor expression-enhancing protein 5 isoform 2 [Dasypus novemcinctus]
ENSG00000129636(ITFG1)	--	39.7705371	1756	39.8028	1589	35.287832	1522	39.50296	1621	37.485227	1566	38.43777891	1730	0.977776621	-0.146107908	normal	0.983651711	-0.042420801	normal	0.97265423	0.176347784	normal	0.985893701	-0.00641345	normal	--	--	--	"K17257|0|hsa:81533|ITFG1, TIP; integrin alpha FG-GAP repeat containing 1; K17257 integrin alpha FG-GAP repeat containing protein 1 (A)"	--	[S]	Function unknown	"Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella;; FG-GAP repeat"	T-cell immunomodulatory protein (Precursor) GN=ITFG1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: T-cell immunomodulatory protein isoform 2 [Canis lupus familiaris]
ENSG00000129646(QRICH2)	--	0.772490627	88	0.862285012	121	0.808599045	106	0.523290951	77	0.523447054	60	1.074810083	137	0.962794496	-0.21937881	normal	0.024991517	-1.01501084	normal	0.911115073	0.357324543	normal	0.765385531	-0.220650799	normal	[N]	Cell motility	--	--	--	--	--	--	Glutamine-rich protein 2 GN=QRICH2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: glutamine-rich protein 2 [Ceratotherium simum simum]
ENSG00000129654(FOXJ1)	--	0.0735784	4	0.0358798	2	0	0	0.0368344	2	0.0890358	4	0.0362218	2	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09402|0|hsa:2302|FOXJ1, FKHL13, HFH-4, HFH4; forkhead box J1; K09402 forkhead box protein J1 (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein J1 GN=FOXJ1 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: forkhead box protein J1 [Ceratotherium simum simum]
ENSG00000129657(SEC14L1)	--	28.77764459	2088	26.60863041	2093	27.49023722	2104	27.36595109	2032	23.32255275	1775	24.64371235	1929	0.985850937	-0.070001355	normal	0.951750097	-0.258976383	normal	0.981526931	-0.133472775	normal	0.437520451	-0.153259369	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	"PRELI-like family;; CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain"	SEC14-like protein 1 GN=SEC14L1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: SEC14-like protein 1 isoform X1 [Galeopterus variegatus] 
ENSG00000129667(RHBDF2)	--	30.19538256	1816	33.0741223	1568	31.67813596	1735	29.70235413	1570	28.76206752	1515	30.74242242	1601	0.955662737	-0.240612719	normal	0.98237981	-0.070964688	normal	0.980042869	-0.12414112	normal	0.46117442	-0.148575838	normal	[R]	General function prediction only	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[T]	Signal transduction mechanisms	Rhomboid serine protease;; Rhomboid family	Inactive rhomboid protein 2 GN=RHBDF2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inactive rhomboid protein 2 isoform X1 [Leptonychotes weddellii]
ENSG00000129673(AANAT)	--	0.81861225	7	0.0739349	2	0.882614204	6	0.2959357	5	0.550058069	1	0.148560072	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	K00669|1.0429e-169|pon:100433977|AANAT; aralkylamine N-acetyltransferase; K00669 arylalkylamine N-acetyltransferase [EC:2.3.1.87] (A)	Tryptophan metabolism (ko00380)	[R]	General function prediction only	Acetyltransferase (GNAT) family	Serotonin N-acetyltransferase GN=AANAT OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: serotonin N-acetyltransferase isoform X1 [Tupaia chinensis] 
ENSG00000129675(ARHGEF6)	--	0.28646779	26	0.16905571	16	0.163688226	14	0.12100111	11	0.07481372	6	0.08742288	8	0.852891829	-1.163295581	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K05729|0|hsa:9459|ARHGEF6, COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX; Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6; K05729 Rho guanine nucleotide exchange factor 6 (A)"	Regulation of actin cytoskeleton (ko04810);; Pancreatic cancer (ko05212)	[F]	Nucleotide transport and metabolism	RhoGEF domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; Calponin homology (CH) domain;; PH domain;; CAMSAP CH domain	Rho guanine nucleotide exchange factor 6 GN=ARHGEF6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 6 [Ceratotherium simum simum]
ENSG00000129680(MAP7D3)	--	6.287730092	639	6.65670145	679	7.469176773	707	5.663945855	573	5.385400005	553	4.917188739	489	0.953716952	-0.187636299	normal	0.87649502	-0.316775314	normal	0.23425971	-0.538773407	normal	0.070744544	-0.347913992	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: microtubule cytoskeleton (GO:0015630);; 	"K16807|0|hsa:79649|MAP7D3, MDP3; MAP7 domain containing 3; K16807 MAP7 domain-containing protein 3 (A)"	--	--	--	MAP7 (E-MAP-115) family	MAP7 domain-containing protein 3 GN=MAP7D3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: MAP7 domain-containing protein 3 [Ceratotherium simum simum]
ENSG00000129682(FGF13)	--	0.250667394	8	0.334058359	10	0.44743491	7	0.262369633	8	0.257884243	3	0.404673269	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|0|ptr:465886|FGF13; fibroblast growth factor 13; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 13 GN=FGF13 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 13-like isoform X1 [Ochotona princeps] 
ENSG00000129691(ASH2L)	--	10.89549692	617	8.899248994	517	9.783894582	557	10.27604451	575	10.23556818	584	10.42339613	581	0.964970959	-0.132199676	normal	0.95976724	0.153953627	normal	0.97197515	0.052430007	normal	0.959389613	0.020068321	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K14964|0|pps:100991595|ASH2L; ash2 (absent, small, or homeotic)-like (Drosophila); K14964 Set1/Ash2 histone methyltransferase complex subunit ASH2 (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	SPRY domain	Set1/Ash2 histone methyltransferase complex subunit ASH2 GN=ASH2L OS=Homo sapiens (Human) PE=1 SV=1	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: set1/Ash2 histone methyltransferase complex subunit ASH2 isoformX2 [Canis lupus familiaris]
ENSG00000129696(TTI2)	--	7.283793	322	6.982048586	318	7.129252043	323	8.510391617	382	8.906453048	391	8.394773895	380	0.941104776	0.214738117	normal	0.912129678	0.275531826	normal	0.937553473	0.225200727	normal	0.369882588	0.238616631	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2454)	TELO2-interacting protein 2 GN=TTI2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: TELO2-interacting protein 2 [Galeopterus variegatus]
ENSG00000129744(ART1)	--	0.0459127	1	0	0	0	0	0.092555	2	0	0	0.0453328	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity (GO:0003956);; Biological Process: protein ADP-ribosylation (GO:0006471);; 	"K06716|0|hsa:417|ART1, ART2, ARTC1, CD296, RT6; ADP-ribosyltransferase 1 (EC:2.4.2.31); K06716 ADP-ribosyltransferase 1 [EC:2.4.2.31] (A)"	--	--	--	NAD:arginine ADP-ribosyltransferase	GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 (Precursor) GN=ART1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 isoform 1 [Dasypus novemcinctus]
ENSG00000129757(CDKN1C)	--	1.647650772	37	0.66873145	16	0.738643256	17	0.545911714	12	1.31598307	30	0.9664321	23	0.180176589	-1.537840972	normal	0.92947482	0.827559754	normal	0.983845821	0.39732494	normal	0.937734595	-0.12680217	normal	--	--	Molecular Function: cyclin-dependent protein serine/threonine kinase inhibitor activity (GO:0004861);; Cellular Component: nucleus (GO:0005634);; Biological Process: cell cycle arrest (GO:0007050);; 	K09993|8.97627e-69|ggo:101140198|uncharacterized protein LOC101140198; K09993 cyclin-dependent kinase inhibitor 1C (A)	Cell cycle (ko04110)	[T]	Signal transduction mechanisms	Cyclin-dependent kinase inhibitor	Cyclin-dependent kinase inhibitor 1C GN=CDKN1C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cyclin-dependent kinase inhibitor 1C [Tupaia chinensis]
ENSG00000129810(SGO1)	--	10.01358478	433	10.99530095	445	12.28462692	509	8.362858607	364	7.766376945	320	7.790079762	317	0.908219311	-0.280174865	normal	0.478089348	-0.495165882	normal	0.0270968	-0.688856132	normal	0.017501395	-0.491905898	normal	--	--	"Cellular Component: chromosome, centromeric region (GO:0000775);; Cellular Component: nucleus (GO:0005634);; Biological Process: meiotic chromosome segregation (GO:0045132);; "	K11580|0|nle:100586546|SGOL1; shugoshin-like 1 (S. pombe); K11580 shugoshin-like 1 (A)	Oocyte meiosis (ko04114)	--	--	Shugoshin N-terminal coiled-coil region;; Shugoshin C terminus	Shugoshin-like 1 GN=SGOL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: shugoshin-like 1 isoform 1 [Ceratotherium simum simum]
ENSG00000129824(RPS4Y1)	--	226.959736	3978	213.5466036	3842	211.534483	3859	110.4207028	2007	121.0520026	2004	95.9664023	1688	1.01E-07	-1.017270256	down	1.65E-06	-0.959868739	normal	4.49E-11	-1.200471569	down	2.57E-15	-1.056808906	down	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02987|0|hsa:6192|RPS4Y1, RPS4Y, S4; ribosomal protein S4, Y-linked 1; K02987 small subunit ribosomal protein S4e (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal family S4e;; RS4NT (NUC023) domain;; S4 domain;; KOW motif	"40S ribosomal protein S4, Y isoform 1 GN=RPS4Y1 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S4-like isoform 1 [Sarcophilus harrisii] 
ENSG00000129910(CDH15)	--	0.0689247	4	0	0	0.0822283	4	0	0	0.0166504	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06809|0|hsa:1013|CDH15, CDH14, CDH3, CDHM, MCAD, MRD3; cadherin 15, type 1, M-cadherin (myotubule); K06809 cadherin 15, M-cadherin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-15 (Precursor) GN=CDH15 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cadherin-15 [Galeopterus variegatus]
ENSG00000129911(KLF16)	--	25.34181209	1058	18.74118651	918	21.7206997	989	19.29399286	803	16.4807155	757	13.45412293	643	0.625424203	-0.427983986	normal	0.899997282	-0.29908388	normal	0.040246961	-0.628242393	normal	0.005772431	-0.450358489	normal	[R]	General function prediction only	--	"K09208|6.68637e-89|hsa:83855|KLF16, BTEB4, DRRF, NSLP2; Kruppel-like factor 16; K09208 krueppel-like factor 9/13/14/16 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Krueppel-like factor 16 GN=KLF16 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: Krueppel-like factor 16, partial [Camelus bactrianus]"
ENSG00000129925(TMEM8A)	--	31.50361696	1738	29.01956138	1582	26.58606546	1511	28.39092049	1600	31.26132101	1610	31.87432346	1792	0.977108282	-0.150050132	normal	0.9843037	0.003880853	normal	0.956357878	0.237556965	normal	0.917992512	0.029179536	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3522)	Transmembrane protein 8A (Precursor) GN=TMEM8A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transmembrane protein 8A [Felis catus]
ENSG00000129932(DOHH)	--	9.39684	274	9.97266874	322	11.59824	359	10.61830443	316	10.366946	330	11.64211	310	0.952208608	0.174007297	normal	0.967267817	0.013914228	normal	0.939856944	-0.219013286	normal	0.970076248	-0.019394348	normal	[C]	Energy production and conversion	--	"K06072|0|hsa:83475|DOHH, HLRC1, hDOHH; deoxyhypusine hydroxylase/monooxygenase (EC:1.14.99.29); K06072 deoxyhypusine monooxygenase [EC:1.14.99.29] (A)"	--	[R]	General function prediction only	HEAT repeats;; PBS lyase HEAT-like repeat;; HEAT repeat;; HEAT-like repeat	Deoxyhypusine hydroxylase {ECO:0000255|HAMAP-Rule:MF_03101} OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: deoxyhypusine hydroxylase-like isoform X1 [Mustela putorius furo] 
ENSG00000129933(MAU2)	--	6.268470018	627	6.209056032	596	6.370753864	645	6.285674	623	6.616417683	657	6.979098077	700	0.973423354	-0.039967291	normal	0.966849568	0.118867138	normal	0.969519132	0.109517776	normal	0.83344726	0.063281184	normal	--	--	Biological Process: mitotic sister chromatid cohesion (GO:0007064);; 	"K11266|0|rno:290668|Mau2, RGD1308759; MAU2 sister chromatid cohesion factor; K11266 MAternally affected uncoordination (A)"	--	[S]	Function unknown	Cohesin loading factor;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	MAU2 chromatid cohesion factor homolog GN=MAU2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: MAU2 chromatid cohesion factor homolog [Camelus ferus] 
ENSG00000129946(SHC2)	--	1.500638329	59	1.401801206	63	0.943328099	42	2.08243362	90	3.00910103	122	1.706520632	78	0.831429691	0.566359812	normal	0.07977287	0.915964432	normal	0.440359116	0.861686444	normal	0.050859862	0.80035163	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17447|0|hsa:25759|SHC2, SCK, SHCB, SLI; SHC (Src homology 2 domain containing) transforming protein 2; K17447 SHC- transforming protein 2 (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Alcoholism (ko05034);; Bacterial invasion of epithelial cells (ko05100);; Glioma (ko05214);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; SH2 domain	SHC-transforming protein 2 GN=SHC2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: SHC-transforming protein 2 [Odobenus rosmarus divergens]
ENSG00000129951(PLPPR3)	--	11.54525931	357	8.639518	294	8.477707235	288	4.354554106	142	8.400677166	271	4.128934131	152	1.28E-08	-1.351303665	down	0.957521944	-0.138209118	normal	0.001519419	-0.923499385	normal	0.031073169	-0.753741168	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	PAP2 superfamily	Lipid phosphate phosphatase-related protein type 3 GN=LPPR3 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: lipid phosphate phosphatase-related protein type 3-like [Chrysochloris asiatica]
ENSG00000129968(ABHD17A)	--	32.76135065	866	27.73403516	776	29.71704326	829	33.01644119	900	32.5359149	869	28.64046501	790	0.977859791	0.024682757	normal	0.967413205	0.141612077	normal	0.974656943	-0.077665738	normal	0.926653849	0.028960807	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Prolyl oligopeptidase family;; Dienelactone hydrolase family	Alpha/beta hydrolase domain-containing protein 17A (Precursor) GN=ABHD17A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	hypothetical protein PANDA_015524 [Ailuropoda melanoleuca]
ENSG00000129988(LBP)	--	0.0292132	1	0	0	0.0573767	1	0.0580995	2	0.651276	22	0.63445	22	--	--	--	0.001214485	3.948623584	up	0.008435881	3.220813744	up	--	--	--	--	--	Molecular Function: lipid binding (GO:0008289);; 	"K05399|0|hsa:3929|LBP, BPIFD2; lipopolysaccharide binding protein; K05399 lipopolysaccharide-binding protein (A)"	NF-kappa B signaling pathway (ko04064);; Toll-like receptor signaling pathway (ko04620);; Salmonella infection (ko05132);; Tuberculosis (ko05152)	[V]	Defense mechanisms	"LBP / BPI / CETP family, C-terminal domain;; LBP / BPI / CETP family, N-terminal domain"	Lipopolysaccharide-binding protein (Precursor) GN=LBP OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: lipopolysaccharide-binding protein-like [Galeopterus variegatus]
ENSG00000129990(SYT5)	--	0.57906487	7	0.104965858	7	0.100214273	6	0.088925347	6	0.13565707	8	0.499430302	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-5 GN=SYT5 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-5 isoform X2 [Leptonychotes weddellii]
ENSG00000129991(TNNI3)	--	4.240752031	28	2.251886898	22	1.33595	17	1.373876562	22	2.984508031	33	2.027424058	25	0.981551304	-0.356623471	normal	0.965386526	0.533427165	normal	0.978313328	0.510461673	normal	0.812924527	0.234590745	normal	--	--	Cellular Component: troponin complex (GO:0005861);; 	"K12044|5.69657e-104|ptg:102964327|TNNI3; troponin I type 3 (cardiac); K12044 troponin I, cardiac muscle (A)"	cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Troponin;; Troponin I residues 1-32	"Troponin I, cardiac muscle GN=TNNI3 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: troponin I, cardiac muscle, partial [Panthera tigris altaica]"
ENSG00000129993(CBFA2T3)	--	0.237207556	12	0.129095858	5	0.105574074	7	0.043739981	1	0.222007414	15	0.066902686	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	NHR2 domain like;; NHR1 homology to TAF;; MYND finger	Protein CBFA2T3 GN=CBFA2T3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: protein CBFA2T3 isoform 1 [Ceratotherium simum simum]
ENSG00000130005(GAMT)	--	25.21555929	480	21.14428513	416	29.02864903	574	21.33566527	417	21.58847315	419	20.59533254	409	0.93460158	-0.233018207	normal	0.969232409	-0.011019926	normal	0.416563001	-0.4956866	normal	0.260537291	-0.260419007	normal	--	--	--	"K00542|6.12e-125|hsa:2593|GAMT, CCDS2, HEL-S-20, PIG2, TP53I2; guanidinoacetate N-methyltransferase (EC:2.1.1.2); K00542 guanidinoacetate N-methyltransferase [EC:2.1.1.2] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Arginine and proline metabolism (ko00330)"	[E]	Amino acid transport and metabolism	--	Guanidinoacetate N-methyltransferase GN=GAMT OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: guanidinoacetate N-methyltransferase [Orycteropus afer afer]
ENSG00000130021(PUDP)	--	16.186047	567	16.29601577	579	16.321843	567	19.41759013	690	19.92888168	695	23.97090109	848	0.928381227	0.251796085	normal	0.934196583	0.24144681	normal	0.130923149	0.571170249	normal	0.051199282	0.361849309	normal	[R]	General function prediction only	--	"K17623|0|hsa:8226|HDHD1, DXF68S1E, FAM16AX, GS1, HDHD1A; haloacid dehalogenase-like hydrolase domain containing 1 (EC:3.1.3.n6); K17623 pseudouridine-5'-monophosphatase [EC:3.1.3.-] (A)"	--	[R]	General function prediction only	Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like	Pseudouridine-5'-monophosphatase GN=HDHD1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: pseudouridine-5'-monophosphatase [Odobenus rosmarus divergens]
ENSG00000130023(ERMARD)	--	7.14135352	242	6.343854832	213	5.269904022	196	6.9137027	250	8.0341048	277	8.380575539	278	0.967013604	0.015988911	normal	0.858374569	0.355387825	normal	0.600522476	0.492732026	normal	0.342423194	0.285257866	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4209)	Endoplasmic reticulum membrane-associated RNA degradation protein GN=ERMARD OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein C6orf70 homolog [Ceratotherium simum simum]
ENSG00000130024(PHF10)	--	15.28677044	835	14.18024079	781	15.43865264	796	16.21122277	878	16.12569499	866	13.773581	804	0.977054789	0.041537942	normal	0.969455557	0.127383607	normal	0.977015937	0.006124052	normal	0.837129318	0.057686596	normal	--	--	--	--	--	[R]	General function prediction only	PHD-finger	PHD finger protein 10 GN=PHF10 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: PHD finger protein 10 isoform X1 [Monodelphis domestica]
ENSG00000130038(CRACR2A)	--	0.431896408	25	0.36138911	20	0.922375701	35	1.073897165	59	0.906676679	50	0.582684922	31	0.204495002	1.160279573	normal	0.234531123	1.239396797	normal	0.981911093	-0.175323887	normal	0.16915137	0.785267764	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K17199|0|hsa:84766|CRACR2A, EFCAB4B; calcium release activated channel regulator 2A; K17199 Ras and EF-hand domain-containing protein (A)"	--	--	--	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF-hand domain pair;; 50S ribosome-binding GTPase	EF-hand calcium-binding domain-containing protein 4B GN=CRACR2A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: EF-hand calcium-binding domain-containing protein 4B [Ceratotherium simum simum]
ENSG00000130045(NXNL2)	--	1.104374407	28	2.674955162	58	1.665269499	33	1.271821135	26	1.610778591	30	1.510904437	26	0.985572649	-0.130323981	normal	0.539234356	-0.937913294	normal	0.978576762	-0.334915899	normal	0.400701097	-0.558987266	normal	--	--	--	"K17609|9.51534e-113|hsa:158046|NXNL2, C9orf121, RDCVF2; nucleoredoxin-like 2 (EC:1.8.1.8); K17609 nucleoredoxin [EC:1.8.1.8] (A)"	--	[R]	General function prediction only	Thioredoxin-like	Nucleoredoxin-like protein 2 GN=NXNL2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: nucleoredoxin-like protein 2 [Condylura cristata]
ENSG00000130052(STARD8)	--	0.987080671	101	0.519274902	55	0.774727674	83	0.615564805	64	0.941101282	97	0.658768246	69	0.617188557	-0.676007067	normal	0.433946538	0.780763674	normal	0.958450974	-0.269414771	normal	0.921405102	-0.075930582	normal	--	--	Biological Process: signal transduction (GO:0007165);; Molecular Function: lipid binding (GO:0008289);; 	--	--	[T]	Signal transduction mechanisms	START domain;; RhoGAP domain	StAR-related lipid transfer protein 8 GN=STARD8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: stAR-related lipid transfer protein 8 isoform X1 [Galeopterus variegatus]
ENSG00000130054(FAM155B)	--	4.39232	204	4.89907	245	4.26286	206	4.57004	226	4.70759	216	4.87671	250	0.961472061	0.116090461	normal	0.945608449	-0.201849007	normal	0.92411759	0.269195815	normal	0.900535826	0.058171945	normal	--	--	--	--	--	--	--	--	Transmembrane protein FAM155B GN=FAM155B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein FAM155B [Eptesicus fuscus]
ENSG00000130055(GDPD2)	--	0	0	0	0	0	0	0.052117141	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; 	K01124|0|ptr:465687|GDPD2; glycerophosphodiester phosphodiesterase domain containing 2; K01124 glycerophosphoinositol inositolphosphodiesterase [EC:3.1.4.43] (A)	--	[C]	Energy production and conversion	Glycerophosphoryl diester phosphodiesterase family	Glycerophosphoinositol inositolphosphodiesterase GDPD2 GN=GDPD2 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: glycerophosphoinositol inositolphosphodiesterase GDPD2 isoform X1 [Galeopterus variegatus]
ENSG00000130066(SAT1)	--	144.4100581	3788	120.375353	3102	110.5654462	3021	208.0236473	4659	261.682499	6471	261.885046	6384	0.967604884	0.267653709	normal	7.84E-08	1.039005106	up	1.07E-08	1.070765776	up	0.001183183	0.801018877	normal	[KR]	Transcription;; General function prediction only	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	"K00657|1.50777e-124|ptr:465538|SAT1, SAT; spermidine/spermine N1-acetyltransferase 1; K00657 diamine N-acetyltransferase [EC:2.3.1.57] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain	Diamine acetyltransferase 1 GN=SAT1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: diamine acetyltransferase 1 [Tupaia chinensis]
ENSG00000130119(GNL3L)	--	17.441474	1924	21.3047	2293	21.36278	2266	15.07544	1650	16.63269	1756	16.91341	1878	0.952089835	-0.25225724	normal	0.755662694	-0.406063035	normal	0.942506348	-0.279037363	normal	0.0486261	-0.315727863	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	K14538|0|hsa:54552|GNL3L; guanine nucleotide binding protein-like 3 (nucleolar)-like; K14538 nuclear GTP-binding protein (A)	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	50S ribosome-binding GTPase;; Ferrous iron transport protein B;; Elongation factor Tu GTP binding domain	Guanine nucleotide-binding protein-like 3-like protein GN=GNL3L OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: guanine nucleotide-binding protein-like 3-like protein [Odobenus rosmarus divergens]
ENSG00000130147(SH3BP4)	--	39.13074263	3944	38.79559731	3983	38.60667776	3968	14.26391531	1455	13.57606217	1376	14.46631509	1482	0	-1.468489642	down	0	-1.553748687	down	6.66E-16	-1.428230522	down	1.77E-29	-1.484750891	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; ZU5 domain	SH3 domain-binding protein 4 GN=SH3BP4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH3 domain-binding protein 4 [Camelus ferus]
ENSG00000130150(MOSPD2)	--	8.991593	569	12.28120966	748	10.385884	627	7.545641032	455	6.755948083	410	9.595435	606	0.826110892	-0.352327858	normal	0.000148058	-0.886382189	normal	0.972630216	-0.057298508	normal	0.135600094	-0.422742088	normal	--	--	--	--	--	--	--	CRAL/TRIO domain;; MSP (Major sperm protein) domain;; Divergent CRAL/TRIO domain	Motile sperm domain-containing protein 2 GN=MOSPD2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: motile sperm domain-containing protein 2 isoform X2 [Canis lupus familiaris]
ENSG00000130158(DOCK6)	--	4.461697524	588	3.077450944	363	3.48929669	426	3.5779812	442	4.579689035	520	3.418220502	430	0.606321392	-0.441267006	normal	0.451497006	0.495382749	normal	0.970361951	0.005173507	normal	0.996330974	-0.005632948	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Dedicator of cytokinesis;; C2 domain in Dock180 and Zizimin proteins;; Domain of unknown function (DUF3398)	Dedicator of cytokinesis protein 6 GN=DOCK6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 6 isoform 2 [Orcinus orca]
ENSG00000130159(ECSIT)	--	14.4047398	511	17.64844851	581	15.436843	538	14.88736086	494	15.36140431	520	19.3618832	624	0.968888702	-0.079401677	normal	0.953837985	-0.180954916	normal	0.948054785	0.205112608	normal	0.974200785	-0.013482776	normal	--	--	--	K04405|0|pps:100982723|ECSIT; ECSIT signalling integrator; K04405 evolutionarily conserved signaling intermediate in Toll pathway (A)	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Evolutionarily conserved signalling intermediate in Toll pathway;; C-terminal domain of the ECSIT protein	"Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial (Precursor) GN=ECSIT OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial isoform 1 [Trichechus manatus latirostris]"
ENSG00000130164(LDLR)	--	27.45097834	2817	34.25077216	3566	34.24877308	3523	15.08604653	1553	14.03966523	1490	31.92181649	3343	1.37E-05	-0.889270391	normal	2.98E-12	-1.279553688	down	0.989810674	-0.083915578	normal	0.188983002	-0.652099068	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	"K12473|0|hsa:3949|LDLR, FH, FHC, LDLCQ2; low density lipoprotein receptor; K12473 low-density lipoprotein receptor (A)"	Endocytosis (ko04144);; Ovarian steroidogenesis (ko04913);; Bile secretion (ko04976);; Toxoplasmosis (ko05145);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; SMP-30/Gluconolaconase/LRE-like region;; EGF-like domain	Low-density lipoprotein receptor (Precursor) GN=LDLR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor [Ceratotherium simum simum]
ENSG00000130165(ELOF1)	--	45.98106515	654	51.2299434	759	52.48847884	775	56.52858188	834	53.84428649	759	45.18701149	644	0.873706832	0.319258968	normal	0.975612979	-0.021383952	normal	0.915798184	-0.274837851	normal	0.980068961	0.010140403	normal	[R]	General function prediction only	--	--	--	[S]	Function unknown	Transcription elongation factor Elf1 like	Transcription elongation factor 1 homolog GN=ELOF1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	transcription elongation factor 1-like protein [Camelus ferus]
ENSG00000130173(ANGPTL8)	--	0.192629	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Angiopoietin-like protein 8 {ECO:0000305} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: hepatocellular carcinoma-associated protein TD26 [Odobenus rosmarus divergens]
ENSG00000130175(PRKCSH)	--	97.84342757	4643	89.83664728	4398	94.09171092	4567	96.66147261	4679	94.84509334	4532	101.2247127	4871	0.993005208	-0.019682828	normal	0.992500061	0.021866292	normal	0.991997528	0.084652605	normal	0.922806793	0.028341528	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K08288|0|pps:100981178|PRKCSH; protein kinase C substrate 80K-H; K08288 protein kinase C substrate 80K-H (A)	Protein processing in endoplasmic reticulum (ko04141)	[T]	Signal transduction mechanisms	Glucosidase II beta subunit-like;; Glucosidase II beta subunit-like protein;; Glucosidase II beta subunit-like protein;; EF hand;; EF hand;; EF-hand domain	Glucosidase 2 subunit beta (Precursor) GN=PRKCSH OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: glucosidase 2 subunit beta isoform X7 [Balaenoptera acutorostrata scammoni]
ENSG00000130176(CNN1)	--	0.0592959	2	0.311800265	3	0	0	0.199304688	2	0.12749423	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Calponin family repeat;; Calponin homology (CH) domain	Calponin-1 GN=CNN1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: calponin-1 [Camelus ferus] 
ENSG00000130177(CDC16)	--	27.42046035	993	22.33568017	806	26.33457728	943	26.30208916	964	26.98912826	978	24.65216415	888	0.977198587	-0.073477439	normal	0.932280128	0.257189423	normal	0.974908282	-0.094832787	normal	0.940905081	0.024298282	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K03353|0|ptr:452688|CDC16; cell division cycle 16; K03353 anaphase-promoting complex subunit 6 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"Anaphase-promoting complex, cyclosome, subunit 3;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Cell division cycle protein 16 homolog GN=CDC16 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cell division cycle protein 16 homolog isoform X1 [Galeopterus variegatus] 
ENSG00000130182(ZSCAN10)	--	0	0	0	0	0	0	0.149003146	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09230|0|ptr:747677|ZSCAN10; zinc finger and SCAN domain containing 10; K09230 SCAN domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; SCAN domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and SCAN domain-containing protein 10 GN=ZSCAN10 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 10 [Equus przewalskii]
ENSG00000130193(THEM6)	--	25.35029	928	21.822524	826	25.01342	956	21.82646	806	20.38608	741	22.19092	818	0.943154475	-0.233761503	normal	0.959729176	-0.177750993	normal	0.94427401	-0.232802664	normal	0.271136083	-0.217455331	normal	--	--	--	--	--	[R]	General function prediction only	Thioesterase-like superfamily	Protein THEM6 (Precursor) GN=THEM6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein THEM6 [Lipotes vexillifer]
ENSG00000130202(NECTIN2)	--	69.31292007	2981	51.8208073	2374	57.9688458	2688	68.69725	3074	82.76857	3578	55.08334	2442	0.990267637	0.013481684	normal	0.141189122	0.570109151	normal	0.983141911	-0.146674766	normal	0.638639343	0.155548745	normal	--	--	--	"K06531|0|hsa:5819|PVRL2, CD112, HVEB, PRR2, PVRR2; poliovirus receptor-related 2 (herpesvirus entry mediator B); K06531 poliovirus receptor-related protein 2 (A)"	Cell adhesion molecules (CAMs) (ko04514);; Adherens junction (ko04520);; Herpes simplex infection (ko05168)	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain	Nectin-2 (Precursor) GN=PVRL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: poliovirus receptor-related protein 2 isoform X1 [Vicugna pacos]
ENSG00000130203(APOE)	--	33.45352084	601	34.40447992	666	30.71717782	600	10.29529157	194	20.061918	354	11.7629307	217	1.89E-15	-1.65428263	down	6.32E-05	-0.93025168	normal	2.54E-12	-1.469132123	down	5.44E-11	-1.307927772	down	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K04524|0|hsa:348|APOE, AD2, APO-E, LDLCQ5, LPG; apolipoprotein E; K04524 apolipoprotein E (A)"	Alzheimer's disease (ko05010)	--	--	Apolipoprotein A1/A4/E domain	Apolipoprotein E (Precursor) GN=APOE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: apolipoprotein E isoform X2 [Tupaia chinensis] 
ENSG00000130204(TOMM40)	--	102.74999	3605	112.3916026	3728	113.9498207	4011	125.1318212	4356	120.9938	4086	92.0175844	3066	0.974001429	0.242078465	normal	0.989482498	0.110817837	normal	0.821557001	-0.395724523	normal	1	-0.00129987	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: transmembrane transport (GO:0055085);; 	K11518|0|bacu:103004174|TOMM40; translocase of outer mitochondrial membrane 40 homolog (yeast); K11518 mitochondrial import receptor subunit TOM40 (A)	Amyotrophic lateral sclerosis (ALS) (ko05014)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Eukaryotic porin	Mitochondrial import receptor subunit TOM40 homolog GN=TOMM40 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import receptor subunit TOM40 homolog [Orcinus orca]
ENSG00000130208(APOC1)	--	65.99220148	414	81.38765491	464	84.19453356	536	23.52743101	100	17.77972889	109	12.87691589	99	0	-2.063518995	down	0	-2.095857596	down	0	-2.427143246	down	9.26E-28	-2.219602065	down	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	Apolipoprotein C-I (ApoC-1)	Truncated apolipoprotein C-I (Precursor) GN=APOC1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: apolipoprotein C-I [Ursus maritimus]
ENSG00000130222(GADD45G)	--	0.152499068	2	0	0	0	0	0.0658615	1	0.14741033	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04402|1.77938e-100|hsa:10912|GADD45G, CR6, DDIT2, GADD45gamma, GRP17; growth arrest and DNA-damage-inducible, gamma; K04402 growth arrest and DNA-damage-inducible protein (A)"	MAPK signaling pathway (ko04010);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115)	--	--	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	Growth arrest and DNA damage-inducible protein GADD45 gamma GN=GADD45G OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: growth arrest and DNA damage-inducible protein GADD45 gamma [Camelus bactrianus]
ENSG00000130224(LRCH2)	--	1.152596618	90	0.780011845	61	1.011604907	78	0.076971105	6	0.098913882	7	0.06445355	5	1.59E-14	-3.629818177	down	7.17E-08	-2.895785961	down	1.23E-12	-3.617191497	down	1.72E-13	-3.69070988	down	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Calponin homology (CH) domain;; Leucine rich repeat	Leucine-rich repeat and calponin homology domain-containing protein 2 GN=LRCH2 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: leucine-rich repeat and calponin homology domain-containing protein 2 [Oryctolagus cuniculus]
ENSG00000130227(XPO7)	--	32.47426783	2882	30.25260727	2674	33.94742414	2873	32.29776964	2851	31.27554796	2805	32.02637134	2899	0.989450961	-0.046409684	normal	0.988759365	0.047548491	normal	0.989934839	0.004703434	normal	1	0.000337067	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	K18460|0|fca:101091441|XPO7; exportin 7; K18460 exportin-7 (A)	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Importin-beta N-terminal domain	Exportin-7 GN=XPO7 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exportin-7 isoform 1 [Orcinus orca] 
ENSG00000130234(ACE2)	--	0	0	0	0	0	0	0.01550771	1	0.015260616	0	0.015594816	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: peptidyl-dipeptidase activity (GO:0008241);; Cellular Component: membrane (GO:0016020);; 	"K09708|0|hsa:59272|ACE2, ACEH; angiotensin I converting enzyme 2 (EC:3.4.17.23); K09708 angiotensin-converting enzyme 2 [EC:3.4.17.23] (A)"	Renin-angiotensin system (ko04614);; Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Angiotensin-converting enzyme	Processed angiotensin-converting enzyme 2 (Precursor) GN=ACE2 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: angiotensin-converting enzyme 2 [Equus przewalskii]
ENSG00000130244(FAM98C)	--	22.80641	422	20.238158	377	17.562949	351	19.821977	346	20.089118	337	18.930298	347	0.8787772	-0.316030003	normal	0.949739749	-0.182467826	normal	0.968506753	-0.024719692	normal	0.530077875	-0.180380736	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF2465)	Protein FAM98C GN=FAM98C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM98C [Galeopterus variegatus]
ENSG00000130254(SAFB2)	--	11.83890801	884	13.928773	1138	13.36281929	1041	17.29529	1244	16.76351924	1286	16.14661725	1236	0.49540874	0.461357131	normal	0.971295806	0.154769962	normal	0.946882739	0.2390981	normal	0.112464832	0.276902199	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[K]	Transcription	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; SAP domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Scaffold attachment factor B2 GN=SAFB2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: scaffold attachment factor B2 isoform X2 [Galeopterus variegatus]
ENSG00000130255(RPL36)	--	248.2176728	2204	246.8318943	2252	246.809485	2303	300.6383842	2737	285.7160121	2519	271.0386903	2427	0.946575458	0.2814626	normal	0.982636808	0.14012873	normal	0.987259636	0.067325186	normal	0.397095737	0.16334832	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02920|3.91315e-61|mcf:102136839|60S ribosomal protein L36-like; K02920 large subunit ribosomal protein L36e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L36e	60S ribosomal protein L36 GN=RPL36 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L36 isoform 1 [Orcinus orca]
ENSG00000130270(ATP8B3)	--	2.62587845	174	1.956052469	124	3.106156615	186	1.887938047	118	1.842154566	131	1.12058676	72	0.526157939	-0.58481911	normal	0.966599541	0.057122319	normal	5.62E-06	-1.359100528	down	0.109006295	-0.614289362	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:148229|ATP8B3, ATPIK; ATPase, aminophospholipid transporter, class I, type 8B, member 3 (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Phospholipid-transporting ATPase IK GN=ATP8B3 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: probable phospholipid-transporting ATPase IK [Sus scrofa]
ENSG00000130283(GDF1)	--	7.612308	241	6.39702541	198	7.7105039	255	7.778386357	246	8.0320343	254	8.049076511	270	0.967095491	-0.001199525	normal	0.881772296	0.335633121	normal	0.965046158	0.073745644	normal	0.729785971	0.129329821	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K05495|0|hsa:2657|GDF1, DORV, DTGA3, RAI; growth differentiation factor 1; K05495 growth differentiation factor 1/3 (A)"	--	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain;; TGF-beta propeptide	Embryonic growth/differentiation factor 1 (Precursor) GN=GDF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: embryonic growth/differentiation factor 1 [Odobenus rosmarus divergens]
ENSG00000130287(NCAN)	--	0	0	0	0	0	0	0.014754193	2	0.021405468	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	"K06794|0|hsa:1463|NCAN, CSPG3; neurocan; K06794 neurocan core protein (A)"	--	--	--	Extracellular link domain;; Lectin C-type domain;; Sushi domain (SCR repeat);; EGF-like domain;; Immunoglobulin V-set domain	Neurocan core protein (Precursor) GN=NCAN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neurocan core protein [Galeopterus variegatus]
ENSG00000130294(KIF1A)	--	0.286112543	39	0.125722517	26	0.4892047	29	0.141713553	18	0.864766944	24	0.10709904	21	0.679191623	-1.082086237	normal	0.985248344	-0.12908649	normal	0.97693167	-0.446485153	normal	0.399865595	-0.598063264	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10392|0|hsa:547|KIF1A, ATSV, C2orf20, HSN2C, MRD9, SPG30, UNC104; kinesin family member 1A; K10392 kinesin family member 1 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain;; Kinesin protein;; Kinesin protein 1B;; PH domain;; FHA domain	Kinesin-like protein KIF1B GN=KIF1B OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: kinesin family member 1A isoform X1 [Canis lupus familiaris] 
ENSG00000130299(GTPBP3)	--	9.17173345	410	8.008967544	374	8.67941	384	7.5381201	343	6.995926272	317	5.92291625	257	0.903831923	-0.28706954	normal	0.921751569	-0.258843633	normal	0.217028064	-0.584794914	normal	0.116946447	-0.371080809	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K03650|0|ptr:748414|tRNA modification GTPase GTPBP3, mitochondrial; K03650 tRNA modification GTPase [EC:3.6.-.-] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	"GTP-binding protein TrmE N-terminus;; 50S ribosome-binding GTPase;; Catalytic cysteine-containing C-terminus of GTPase, MnmE;; Dynamin family"	"tRNA modification GTPase GTPBP3, mitochondrial (Precursor) GN=GTPBP3 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tRNA modification GTPase GTPBP3, mitochondrial isoform X1 [Condylura cristata]"
ENSG00000130303(BST2)	--	0.0608421	1	0	0	0	0	0.059762	1	0.296123	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: defense response to virus (GO:0051607);; 	"K06731|7.62764e-84|hsa:684|BST2, CD317, TETHERIN; bone marrow stromal cell antigen 2; K06731 bone marrow stromal cell antigen 2 (A)"	--	--	--	--	Bone marrow stromal antigen 2 (Precursor) GN=BST2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bone marrow stromal antigen 2 [Galeopterus variegatus] 
ENSG00000130304(SLC27A1)	--	5.682135643	352	4.0899503	263	4.282957999	274	2.628226286	165	3.66924897	230	2.388385118	151	6.84E-06	-1.116643901	down	0.941940954	-0.213541302	normal	0.005993204	-0.861418755	normal	0.009724836	-0.724644455	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K08745|0|hsa:376497|SLC27A1, ACSVL5, FATP, FATP1; solute carrier family 27 (fatty acid transporter), member 1; K08745 solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] (A)"	PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	Long-chain fatty acid transport protein 1 GN=SLC27A1 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	long-chain fatty acid transport protein 1 precursor [Bos taurus] 
ENSG00000130305(NSUN5)	--	26.40138	754	23.01379781	661	26.04923243	749	27.02967165	760	24.06705501	669	26.0730326	725	0.976148365	-0.019358079	normal	0.974226025	-0.004061383	normal	0.974812902	-0.055162952	normal	0.93492335	-0.0279367	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; 	"K15264|0|hsa:55695|NSUN5, NOL1, NOL1R, NSUN5A, WBSCR20, WBSCR20A, p120; NOP2/Sun domain family, member 5; K15264 putative methyltransferase [EC:2.1.1.-] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	NOL1/NOP2/sun family	Probable 28S rRNA (cytosine-C(5))-methyltransferase GN=NSUN5 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: putative methyltransferase NSUN5 isoform X2 [Tupaia chinensis]
ENSG00000130307(USHBP1)	--	76.6417079	2198	66.0866743	2089	68.0122713	2132	69.91427	2091	71.3578864	2169	61.025206	1912	0.984622919	-0.102756931	normal	0.986839116	0.032767723	normal	0.977810704	-0.165292481	normal	0.740304548	-0.07801934	normal	--	--	--	--	--	--	--	PDZ domain of MCC-2 bdg protein for Usher syndrome	Usher syndrome type-1C protein-binding protein 1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: Usher syndrome type-1C protein-binding protein 1 [Galeopterus variegatus]
ENSG00000130309(COLGALT1)	--	62.260899	4176	63.70599	4400	61.17971301	4203	54.83277388	3763	50.03211076	3411	55.53452486	3670	0.984598469	-0.181000489	normal	0.854236915	-0.388583184	normal	0.981422016	-0.203852276	normal	0.135917219	-0.258229926	normal	--	--	--	"K11703|0|ptr:455843|GLT25D1; procollagen galactosyltransferase 1; K11703 collagen beta-1,O-galactosyltransferase [EC:2.4.1.50] (A)"	Lysine degradation (ko00310);; Other types of O-glycan biosynthesis (ko00514)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyltransferase family 25 (LPS biosynthesis protein);; Glycosyl transferase family 2	Procollagen galactosyltransferase 1 (Precursor) GN=COLGALT1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: procollagen galactosyltransferase 1 [Canis lupus familiaris]
ENSG00000130311(DDA1)	--	12.1158	880	11.5023	843	11.9762	878	13.7622	991	12.5129	901	11.5318	839	0.969893875	0.140318325	normal	0.975213856	0.074438737	normal	0.975642722	-0.073711677	normal	0.865273703	0.048703428	normal	--	--	--	K11792|4.00995e-71|pps:100989135|DDA1; DET1 and DDB1 associated 1; K11792 DET1- and DDB1-associated protein 1 (A)	--	[S]	Function unknown	Det1 complexing ubiquitin ligase	DET1- and DDB1-associated protein 1 GN=DDA1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DET1- and DDB1-associated protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000130312(MRPL34)	--	53.14728	489	46.00305	471	58.40382	537	47.25517005	477	53.838	458	53.07938	538	0.969387267	-0.066466003	normal	0.968584805	-0.061605419	normal	0.972567897	-0.005591625	normal	0.898386611	-0.043959955	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02914|5.74828e-75|pon:100454510|MRPL34; mitochondrial ribosomal protein L34; K02914 large subunit ribosomal protein L34 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L34	"39S ribosomal protein L34, mitochondrial (Precursor) GN=MRPL34 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L34, mitochondrial [Tupaia chinensis]"
ENSG00000130313(PGLS)	--	52.19010187	774	45.50748008	679	40.89170189	622	41.67189615	634	44.982897	664	52.37995918	780	0.874290795	-0.31798416	normal	0.973127937	-0.053534315	normal	0.875397995	0.3175772	normal	0.959389613	-0.01872877	normal	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K01057|2.0562e-143|hsa:25796|PGLS, 6PGL; 6-phosphogluconolactonase (EC:3.1.1.31); K01057 6-phosphogluconolactonase [EC:3.1.1.31] (A)"	Pentose phosphate pathway (ko00030);; Carbon metabolism (ko01200)	[G]	Carbohydrate transport and metabolism	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	6-phosphogluconolactonase GN=PGLS OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: 6-phosphogluconolactonase [Orcinus orca] 
ENSG00000130332(LSM7)	--	80.0235	500	74.17065	483	62.155558	413	89.54169	607	92.09997	576	84.90175	549	0.9288049	0.248242995	normal	0.936169789	0.231953322	normal	0.731242462	0.401094967	normal	0.173921941	0.289352496	normal	[K]	Transcription	--	"K12626|1.70229e-69|lve:103083602|LSM7; LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae); K12626 U6 snRNA-associated Sm-like protein LSm7 (A)"	RNA degradation (ko03018);; Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm7 GN=LSM7 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U6 snRNA-associated Sm-like protein LSm7 [Lipotes vexillifer]
ENSG00000130338(TULP4)	--	2.844094327	572	3.641476347	706	3.179984223	662	3.549763179	684	3.471792946	741	3.957351288	835	0.940727711	0.226591772	normal	0.974252807	0.048277857	normal	0.865860772	0.32598905	normal	0.356343007	0.199701821	normal	--	--	--	--	--	[R]	General function prediction only	"Tub family;; SOCS box;; WD domain, G-beta repeat"	Tubby-related protein 4 GN=TULP4 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: tubby-related protein 4 isoform X1 [Ochotona princeps]
ENSG00000130340(SNX9)	--	16.81958146	1156	18.3997719	1274	16.20012361	1115	13.13758624	898	12.17587914	838	12.98487848	915	0.735144108	-0.394589436	normal	0.043651204	-0.624848007	normal	0.909169486	-0.293051986	normal	0.005141342	-0.440585721	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17923|0|ptr:472172|SNX9; sorting nexin 9; K17923 sorting nexin-9/18/33 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	WASP-binding domain of Sorting nexin protein;; PX domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Sorting nexin-9 GN=SNX9 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-9 [Orcinus orca]
ENSG00000130347(RTN4IP1)	--	8.60167	227	7.949290045	214	7.9136314	209	7.39332	198	9.04515001	236	6.94545	183	0.941183241	-0.226381864	normal	0.959884981	0.118948854	normal	0.94939574	-0.19841523	normal	0.82445739	-0.096548937	normal	[CR]	Energy production and conversion;; General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[CR]	Energy production and conversion;; General function prediction only	Zinc-binding dehydrogenase;; Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	"Reticulon-4-interacting protein 1, mitochondrial (Precursor) GN=RTN4IP1 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: reticulon-4-interacting protein 1, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000130348(QRSL1)	--	4.113671	292	4.777210469	351	5.7854	380	5.571747	388	5.303576	356	5.613062	389	0.804102822	0.377527867	normal	0.96791223	-0.001016001	normal	0.969197053	0.025379466	normal	0.690306296	0.126393134	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02433|0|hsa:55278|QRSL1, GatA; glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 (EC:6.3.5.7); K02433 aspartyl-tRNA(Asn)/glutamyl-tRNA(Gln) amidotransferase subunit A [EC:6.3.5.6 6.3.5.7] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	Amidase	"Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03150} OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000130349(C6orf203)	--	6.93312567	103	6.920132	110	7.382575163	116	7.968272918	122	6.049283024	96	7.769570998	116	0.956951292	0.210516693	normal	0.956374231	-0.214661882	normal	0.969509408	-0.008184738	normal	1	0.000450075	normal	--	--	--	--	--	[S]	Function unknown	--	Uncharacterized protein C6orf203 GN=C6orf203 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C6orf203 homolog [Loxodonta africana]
ENSG00000130363(RSPH3)	--	1.998753429	222	2.536230764	252	2.646070031	283	3.591846461	339	2.840719	274	2.752268139	281	0.279155112	0.576642316	normal	0.961996632	0.09875714	normal	0.967458687	-0.018424558	normal	0.474741977	0.218443311	normal	--	--	--	--	--	--	--	Radial spoke protein 3	Radial spoke head protein 3 homolog GN=RSPH3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: radial spoke head protein 3 homolog [Odobenus rosmarus divergens]
ENSG00000130377(ACSBG2)	--	0.0196793	1	0	0	0	0	0	0	0.057433145	2	0.039092209	2	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K15013|0|hsa:81616|ACSBG2, BGR, BRGL, PRTD-NY3, PRTDNY3; acyl-CoA synthetase bubblegum family member 2 (EC:6.2.1.3); K15013 long-chain-fatty-acid--CoA ligase ACSBG [EC:6.2.1.3] (A)"	Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	AMP-binding enzyme	Long-chain-fatty-acid--CoA ligase ACSBG2 GN=ACSBG2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: long-chain-fatty-acid--CoA ligase ACSBG2 [Ceratotherium simum simum]
ENSG00000130382(MLLT1)	--	14.7159	1335	15.6247	1421	14.921	1384	14.524	1310	14.4776	1316	17.118	1571	0.981577748	-0.058037762	normal	0.976196893	-0.132027569	normal	0.971446331	0.174368855	normal	1	-0.000936515	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15187|0|hsa:4298|MLLT1, ENL, LTG19, YEATS1; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1; K15187 YEATS domain-containing protein 1/3 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	YEATS family	Protein ENL GN=MLLT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: protein ENL [Ochotona princeps]
ENSG00000130383(FUT5)	--	175.1008143	1006	172.9869347	1048	180.5799199	1077	179.0448847	1061	190.474688	1080	168.502421	1014	0.979145102	0.045893835	normal	0.979640893	0.021934858	normal	0.976595983	-0.095114372	normal	0.978774325	-0.010207226	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: fucosyltransferase activity (GO:0008417);; Cellular Component: membrane (GO:0016020);; 	"K07633|0|hsa:2527|FUT5, FUC-TV; fucosyltransferase 5 (alpha (1,3) fucosyltransferase) (EC:2.4.1.65); K07633 galactoside alpha-1,3-fucosyltransferase 5 [EC:2.4.1.65] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Glycosyltransferase family 10 (fucosyltransferase)	"Alpha-(1,3)-fucosyltransferase 5 GN=FUT5 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-(1,3)-fucosyltransferase 5-like [Galeopterus variegatus]"
ENSG00000130396(AFDN)	--	12.01921608	1631	10.62859919	1518	12.47088777	1481	11.93336423	1652	12.02092188	1642	11.32114586	1444	0.984926216	-0.012363786	normal	0.981524319	0.091767863	normal	0.983189557	-0.044746066	normal	0.972552315	0.011615544	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K05702|0|mcc:693560|MLLT4; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4; K05702 afadin (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Adherens junction (ko04520);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670)	[Z]	Cytoskeleton	Ras association (RalGDS/AF-6) domain;; DIL domain;; PDZ domain (Also known as DHR or GLGF);; FHA domain	Afadin GN=MLLT4 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	hypothetical protein PANDA_007256 [Ailuropoda melanoleuca]
ENSG00000130402(ACTN4)	--	453.6442342	32298	476.2432785	34281	519.0494589	37576	661.9850934	47256	631.0296924	44017	525.7998749	38232	0.731515439	0.518199934	normal	0.986459616	0.339211833	normal	0.998768683	0.016677066	normal	0.185117982	0.292675922	normal	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	"K05699|0|ptr:456010|ACTN4; actinin, alpha 4; K05699 actinin alpha (A)"	Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Amoebiasis (ko05146);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Ca2+ insensitive EF hand;; CAMSAP CH domain;; EF hand;; EF-hand domain	Alpha-actinin-4 GN=ACTN4 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	alpha-actinin-4 [Bos taurus] 
ENSG00000130413(STK33)	--	1.52481238	43	0.719326052	36	1.886410702	50	4.586344985	142	3.263490151	156	2.069342514	106	5.82E-07	1.658222673	up	1.66E-10	2.049137406	up	0.032329246	1.053401611	normal	2.17E-06	1.625572173	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K08813|0|ptr:466437|STK33; serine/threonine kinase 33; K08813 serine/threonine kinase 33 [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 33 GN=STK33 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 33 [Ceratotherium simum simum]
ENSG00000130414(NDUFA10)	--	59.11678597	1563	62.45939877	1650	60.77888473	1587	45.874505	1315	43.626705	1216	48.52847376	1331	0.930103345	-0.279786934	normal	0.526752013	-0.461254811	normal	0.94190562	-0.261810203	normal	0.037198766	-0.334907425	normal	--	--	--	"K03954|0|mcc:697681|NDUFA10; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa; K03954 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 10 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Deoxynucleoside kinase	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial (Precursor) GN=NDUFA10 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial isoform 1 [Equus caballus]"
ENSG00000130427(EPO)	--	0	0	0	0	0	0	0.0440311	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	"K05437|4.75735e-105|hsa:2056|EPO, EP, MVCD2; erythropoietin; K05437 erythropoietin (A)"	Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640)	--	--	Erythropoietin/thrombopoietin	Erythropoietin (Precursor) GN=EPO OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: erythropoietin isoform X1 [Galeopterus variegatus]
ENSG00000130429(ARPC1B)	--	239.6549382	6011	250.3856532	6339	237.6186951	5962	268.0255807	6852	253.5218614	6394	258.6755301	6449	0.990954389	0.158050012	normal	0.994377343	-0.008960953	normal	0.993015535	0.104962047	normal	0.73222535	0.083574728	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K05757|0|pps:100975648|ARPC1B; actin related protein 2/3 complex, subunit 1B, 41kDa; K05757 actin related protein 2/3 complex, subunit 1A/1B (A)"	Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Actin-related protein 2/3 complex subunit 1B GN=ARPC1B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: actin-related protein 2/3 complex subunit 1B [Ochotona princeps]
ENSG00000130433(CACNG6)	--	15.60055476	1365	13.72887797	1360	11.7893707	1212	6.9253108	478	10.19196123	687	7.504068049	526	2.22E-16	-1.541577037	down	1.03E-06	-1.005046821	down	4.91E-10	-1.210186501	down	2.06E-18	-1.240185557	down	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K04871|1.22268e-109|ptr:749208|CACNG6; calcium channel, voltage-dependent, gamma subunit 6; K04871 voltage-dependent calcium channel gamma-6 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	--	--	PMP-22/EMP/MP20/Claudin tight junction;; PMP-22/EMP/MP20/Claudin family	Voltage-dependent calcium channel gamma-6 subunit GN=CACNG6 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent calcium channel gamma-6 subunit isoform X1 [Leptonychotes weddellii]
ENSG00000130449(ZSWIM6)	--	4.95044	487	5.521195	533	5.37728	519	7.04605	680	6.59048	640	7.39107	720	0.56683624	0.449575559	normal	0.93280938	0.241882792	normal	0.513172429	0.462821035	normal	0.04091353	0.385539744	normal	[S]	Function unknown	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[S]	Function unknown	--	Zinc finger SWIM domain-containing protein 6 GN=ZSWIM6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger SWIM domain-containing protein 6 [Orcinus orca]
ENSG00000130475(FCHO1)	--	14.49305511	478	10.78998365	345	14.2018798	484	7.7206967	243	11.270091	348	4.84073727	160	2.40E-05	-1.002276881	down	0.967732948	-0.008896784	normal	2.81E-13	-1.596103587	down	0.032041459	-0.820918967	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Muniscin C-terminal mu homology domain;; Fes/CIP4, and EFC/F-BAR homology domain"	FCH domain only protein 1 GN=FCHO1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: FCH domain only protein 1 isoform X1 [Leptonychotes weddellii]
ENSG00000130477(UNC13A)	--	1.28719772	313	1.37694375	328	1.102931401	272	0.151907448	36	0.215545208	52	0.201500208	49	0	-3.096988175	down	0	-2.643464761	down	0	-2.445043746	down	1.15E-26	-2.756946022	down	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	"K15293|0|hsa:23025|UNC13A, Munc13-1; unc-13 homolog A (C. elegans); K15293 protein unc-13 (A)"	Synaptic vesicle cycle (ko04721)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Munc13 (mammalian uncoordinated) homology domain;; C2 domain;; Domain of Unknown Function (DUF1041);; Phorbol esters/diacylglycerol binding domain (C1 domain)	Protein unc-13 homolog A GN=UNC13A OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: protein unc-13 homolog A isoform X1 [Mustela putorius furo] 
ENSG00000130479(MAP1S)	--	11.39826888	732	9.425869289	651	9.565673694	689	13.0843971	676	10.04825287	660	8.476062122	600	0.965040789	-0.145335104	normal	0.97406362	-0.001614352	normal	0.948702667	-0.207344818	normal	0.637619715	-0.119454401	normal	--	--	--	"K10429|0|hsa:55201|MAP1S, BPY2IP1, C19orf5, MAP8, VCY2IP-1, VCY2IP1; microtubule-associated protein 1S; K10429 microtubule-associated protein 1 (A)"	--	[Z]	Cytoskeleton	--	MAP1S light chain GN=MAP1S OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: microtubule-associated protein 1S isoform X1 [Canis lupus familiaris]
ENSG00000130508(PXDN)	--	33.43799729	3969	19.6235328	2685	24.66559255	3334	14.85304805	2006	14.30095025	2036	14.81585019	1934	1.12E-07	-1.014722247	down	0.725883122	-0.420338252	normal	0.000313699	-0.793479212	normal	0.001757622	-0.762209485	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Animal haem peroxidase;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Leucine rich repeat;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; von Willebrand factor type C domain;; Leucine-rich repeat;; Leucine Rich Repeat;; Beta-microseminoprotein (PSP-94);; Zona-pellucida-binding protein (Sp38)	Peroxidasin homolog (Precursor) GN=PXDN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: peroxidasin homolog isoform 1 [Dasypus novemcinctus]
ENSG00000130511(SSBP4)	--	38.63838781	1143	35.2032791	1088	34.19646938	1081	31.14456362	880	30.30434481	900	21.93888425	668	0.69633548	-0.407455969	normal	0.908529949	-0.294657122	normal	0.007191975	-0.701477248	normal	0.00394065	-0.458046317	normal	--	--	--	--	--	[LKR]	"Replication, recombination and repair;; Transcription;; General function prediction only"	"Single-stranded DNA binding protein, SSDP"	Single-stranded DNA-binding protein 4 GN=SSBP4 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: single-stranded DNA-binding protein 4 isoform 1 [Odobenus rosmarus divergens]
ENSG00000130513(GDF15)	--	392.0135151	6556	432.7100417	7380	379.15829	6619	71.3087241	1221	100.28439	1694	279.6310204	4789	0	-2.454085691	down	0	-2.143609985	down	0.599658675	-0.475052099	normal	0.000721604	-1.433124946	down	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K05504|0|hsa:9518|GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB; growth differentiation factor 15; K05504 growth differentiation factor 15 (A)"	--	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain	Growth/differentiation factor 15 (Precursor) GN=GDF15 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: growth/differentiation factor 15 [Physeter catodon]
ENSG00000130517(PGPEP1)	--	5.51394706	606	6.584611497	592	5.581719735	558	4.155647288	464	3.7703808	365	4.215059069	576	0.6857135	-0.414819215	normal	0.013505831	-0.716771385	normal	0.972536799	0.037412447	normal	0.1595548	-0.342461726	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K01304|6.89432e-155|ptr:748692|PGPEP1; pyroglutamyl-peptidase I; K01304 pyroglutamyl-peptidase [EC:3.4.19.3] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Pyroglutamyl peptidase	Pyroglutamyl-peptidase 1 GN=PGPEP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	pyroglutamyl-peptidase 1 [Bos taurus] 
ENSG00000130518(KIAA1683)	--	0.629796662	20	0.23258751	23	0.307274985	28	0.233615341	20	0.156429536	12	0.16041998	17	0.989125045	-0.028632677	normal	0.950295282	-0.878800022	normal	0.961166391	-0.680572903	normal	0.494966685	-0.556516345	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	IQ calmodulin-binding motif	Uncharacterized protein KIAA1683 GN=KIAA1683 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein KIAA1683 homolog [Galeopterus variegatus]
ENSG00000130520(LSM4)	--	100.838311	2008	99.426803	2008	94.992897	1977	101.7151484	1937	87.0336979	1851	109.4784	2233	0.984854182	-0.082703142	normal	0.98013513	-0.138772037	normal	0.978101614	0.167258485	normal	0.965475915	-0.014095037	normal	[K]	Transcription	--	"K12623|2.28488e-63|mcf:102115467|LSM4; LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae); K12623 U6 snRNA-associated Sm-like protein LSm4 (A)"	RNA degradation (ko03018);; Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm4 GN=LSM4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U6 snRNA-associated Sm-like protein LSm4 [Sorex araneus]
ENSG00000130522(JUND)	--	125.8567	2945	117.6710638	3236	88.65992	2353	78.7881	2044	82.38052	2028	100.8061	2576	0.146353169	-0.557353507	normal	0.00725421	-0.695166164	normal	0.984779319	0.122264707	normal	0.13715447	-0.3813016	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04449|8.08776e-127|lve:103085721|JUND; jun D proto-oncogene; K04449 transcription factor jun-D (A)	MAPK signaling pathway (ko04010);; Osteoclast differentiation (ko04380)	[K]	Transcription	Jun-like transcription factor;; bZIP transcription factor;; bZIP Maf transcription factor;; Basic region leucine zipper	Transcription factor jun-D GN=JUND OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor jun-D [Camelus bactrianus] 
ENSG00000130528(HRC)	--	0	0	0.030431269	2	0	0	0.061680392	4	0.015330314	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Histidine-rich Calcium-binding repeat region	Sarcoplasmic reticulum histidine-rich calcium-binding protein (Precursor) GN=HRC OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: sarcoplasmic reticulum histidine-rich calcium-binding protein isoform X2 [Canis lupus familiaris]
ENSG00000130529(TRPM4)	--	9.550193564	625	8.823528247	535	7.926627292	535	5.886892636	383	6.782219934	437	5.401181	323	0.00692154	-0.735010908	normal	0.880554216	-0.312353357	normal	0.01004681	-0.733598541	normal	0.0015294	-0.590125041	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04979|0|pps:100968799|TRPM4; transient receptor potential cation channel, subfamily M, member 4; K04979 transient receptor potential cation channel subfamily M member 4 (A)"	Insulin secretion (ko04911)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein	Transient receptor potential cation channel subfamily M member 4 GN=TRPM4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily M member 4 isoform X2 [Mustela putorius furo] 
ENSG00000130544(ZNF557)	--	2.039107672	133	2.06884764	148	1.3659589	105	1.663390962	116	1.97320667	130	2.550710614	163	0.952172111	-0.225343515	normal	0.951547491	-0.206261458	normal	0.478096097	0.618980996	normal	0.915887742	0.062815618	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:79230|ZNF557; zinc finger protein 557; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger of C2H2 type"	Zinc finger protein 557 GN=ZNF557 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 558 [Tupaia chinensis]
ENSG00000130545(CRB3)	--	1.086179	11	2.928653	35	0.778079	10	6.83944	57	8.145006	80	7.25963	61	7.82E-05	2.19466657	up	0.059875402	1.137851416	normal	3.86E-06	2.433318699	up	0.000105573	1.799645237	up	--	--	--	K06090|3.13537e-43|ptr:100614722|CRB3; crumbs family member 3; K06090 crumbs 3 (A)	Tight junction (ko04530)	--	--	--	Protein crumbs homolog 3 (Precursor) GN=CRB3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein crumbs homolog 3 isoform X2 [Galeopterus variegatus]
ENSG00000130558(OLFM1)	--	5.348668964	210	5.80882606	220	5.252400236	187	4.066211808	146	3.080396804	110	4.06801221	147	0.533255483	-0.550394518	normal	0.00120108	-1.011392159	down	0.890169324	-0.35229223	normal	0.028624378	-0.636041534	normal	--	--	--	--	--	[W]	Extracellular structures	Olfactomedin-like domain;; Neurogenesis glycoprotein	Noelin (Precursor) GN=OLFM1 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: noelin isoform 2 [Equus caballus]
ENSG00000130559(CAMSAP1)	--	10.24395302	1599	9.99777736	1613	11.29810215	1806	10.57002983	1698	10.45929684	1652	9.949101368	1569	0.984082778	0.055782241	normal	0.984491438	0.013028621	normal	0.96550914	-0.211054206	normal	0.848304942	-0.049954538	normal	--	--	Molecular Function: calmodulin binding (GO:0005516);; Molecular Function: microtubule binding (GO:0008017);; Molecular Function: spectrin binding (GO:0030507);; Biological Process: neuron projection development (GO:0031175);; 	K17493|0|ptr:464848|CAMSAP1; calmodulin regulated spectrin-associated protein 1; K17493 calmodulin-regulated spectrin-associated protein (A)	--	[Z]	Cytoskeleton	Microtubule-binding calmodulin-regulated spectrin-associated;; CAMSAP CH domain;; Calponin homology (CH) domain	Calmodulin-regulated spectrin-associated protein 1 GN=CAMSAP1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: calmodulin-regulated spectrin-associated protein 1 [Erinaceus europaeus]
ENSG00000130560(UBAC1)	--	18.32169038	756	16.395077	688	18.54174071	785	19.77794615	816	17.911542	735	16.2551	672	0.974076514	0.079195718	normal	0.972690136	0.073752269	normal	0.940944187	-0.2320392	normal	0.942436071	-0.025502231	normal	--	--	--	K12174|0|pps:100971007|UBAC1; UBA domain containing 1; K12174 Kip1 ubiquitination-promoting complex protein 2 (A)	--	--	--	UBA/TS-N domain	Ubiquitin-associated domain-containing protein 1 GN=UBAC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ubiquitin-associated domain-containing protein 1 [Leptonychotes weddellii]
ENSG00000130584(ZBTB46)	--	1.350609373	121	1.352862683	110	0.777433457	69	0.995711513	91	0.9471321	78	0.375342701	35	0.876352735	-0.435500206	normal	0.827503566	-0.509030464	normal	0.360063381	-0.957523433	normal	0.352956672	-0.580795311	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10517|0|hsa:140685|ZBTB46, BTBD4, BZEL, RINZF, ZNF340, dJ583P15.7, dJ583P15.8; zinc finger and BTB domain containing 46; K10517 zinc finger and BTB domain-containing protein 46 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; C2H2-type zinc finger;; Domain of unknown function (DUF3342);; Zinc finger, C2H2 type"	Zinc finger and BTB domain-containing protein 46 GN=ZBTB46 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 46 [Galeopterus variegatus]
ENSG00000130589(HELZ2)	--	3.809996285	723	2.875475	541	3.483638775	680	3.365547655	642	3.494634	648	2.833025747	535	0.951172114	-0.201799165	normal	0.934695807	0.238329253	normal	0.823050403	-0.353399012	normal	0.685658172	-0.112613639	normal	[L]	"Replication, recombination and repair"	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	"AAA domain;; AAA domain;; RNB domain;; AAA domain;; Part of AAA domain;; AAA domain;; UvrD-like helicase C-terminal domain;; PhoH-like protein;; Type III restriction enzyme, res subunit"	Helicase with zinc finger domain 2 GN=HELZ2 OS=Homo sapiens (Human) PE=1 SV=6	AJ	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	PREDICTED: helicase with zinc finger domain 2 [Equus caballus]
ENSG00000130590(SAMD10)	--	0.12756192	5	0.099832389	4	0.097267072	3	0.076472308	3	0.098976313	3	0.02511165	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: sequence-specific DNA binding (GO:0043565);; 	--	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Sterile alpha motif (SAM)/Pointed domain	Sterile alpha motif domain-containing protein 10 GN=SAMD10 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: sterile alpha motif domain-containing protein 10 isoform X2 [Equus przewalskii]
ENSG00000130592(LSP1)	--	0.76985265	13	0.061018778	2	0.294138282	6	0.366891021	7	0.380612712	6	0.754959616	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K14957|0|pps:100971803|LSP1; lymphocyte-specific protein 1; K14957 lymphocyte-specific protein 1 (A)	Tuberculosis (ko05152)	[R]	General function prediction only	Caldesmon	Lymphocyte-specific protein 1 GN=LSP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lymphocyte-specific protein 1 [Ceratotherium simum simum]
ENSG00000130635(COL5A1)	--	15.35851682	2754	11.789213	2289	14.88503158	2554	51.23776796	9762	66.297119	12363	32.044945	6042	0	1.794249337	up	0	2.411044951	up	6.99E-12	1.23348676	up	0.000520714	1.868406646	up	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; 	"K06236|0|hsa:1289|COL5A1; collagen, type V, alpha 1; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; Laminin G domain	Collagen alpha-1(V) chain (Precursor) GN=COL5A1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: collagen alpha-1(V) chain [Vicugna pacos]
ENSG00000130638(ATXN10)	--	73.72099398	2565	79.60569896	2697	74.59335549	2566	74.13526508	2688	94.13686471	3177	78.20551599	2790	0.988920358	0.036720562	normal	0.974927537	0.214771952	normal	0.986299857	0.112388971	normal	0.556239147	0.123833876	normal	--	--	--	--	--	[S]	Function unknown	Spinocerebellar ataxia type 10 protein domain	Ataxin-10 GN=ATXN10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ataxin-10 isoformX1 [Canis lupus familiaris]
ENSG00000130640(TUBGCP2)	--	20.92589761	1692	20.915342	1766	21.05759701	1776	20.91061558	1715	23.22573575	1894	25.116581	2073	0.985304664	-0.011343025	normal	0.98386889	0.07945872	normal	0.967137594	0.214627777	normal	0.664425654	0.097917081	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: spindle pole (GO:0000922);; Cellular Component: microtubule organizing center (GO:0005815);; Biological Process: microtubule nucleation (GO:0007020);; Molecular Function: gamma-tubulin binding (GO:0043015);; 	"K16569|0|hsa:10844|TUBGCP2, GCP-2, GCP2, Grip103, SPBC97, Spc97p, h103p, hGCP2, hSpc97; tubulin, gamma complex associated protein 2; K16569 gamma-tubulin complex component 2 (A)"	--	[Z]	Cytoskeleton	Spc97 / Spc98 family;; Putative binding domain	Gamma-tubulin complex component 2 GN=TUBGCP2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: gamma-tubulin complex component 2 isoform X1 [Tupaia chinensis]
ENSG00000130643(CALY)	--	0.3705789	10	0.0466652	2	0.102323	4	0.187734	8	0.2851019	12	0.113954	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: dopamine receptor signaling pathway (GO:0007212);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: clathrin light chain binding (GO:0032051);; Biological Process: clathrin coat assembly (GO:0048268);; 	"K15493|3.28368e-120|hsa:50632|CALY, DRD1IP, NSG3; calcyon neuron-specific vesicular protein; K15493 neuron-specific vesicular protein calcyon (A)"	Dopaminergic synapse (ko04728)	--	--	D1 dopamine receptor-interacting protein (calcyon)	Neuron-specific vesicular protein calcyon GN=CALY OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: neuron-specific vesicular protein calcyon [Tupaia chinensis]
ENSG00000130649(CYP2E1)	--	0.140998776	2	0	0	0	0	0	0	0.251839158	0	0.064078691	2	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07415|0|hsa:1571|CYP2E1, CPE1, CYP2E, P450-J, P450C2E; cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7); K07415 cytochrome P450, family 2, subfamily E, polypeptide 1 [EC:1.14.13.-] (A)"	Steroid hormone biosynthesis (ko00140);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	"Cytochrome P450 2E1, N-terminally processed GN=CYP2E1 OS=Homo sapiens (Human) PE=1 SV=1"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2E1-like [Tupaia chinensis] 
ENSG00000130653(PNPLA7)	--	1.2035508	122	0.764326	79	0.67708656	71	0.388350117	38	0.581252506	59	0.738579571	76	2.01E-06	-1.673722356	down	0.92256092	-0.432938446	normal	0.972859115	0.088075445	normal	0.2274788	-0.67247254	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K14676|0|hsa:375775|PNPLA7, C9orf111, NTE-R1, NTEL1; patatin-like phospholipase domain containing 7; K14676 lysophospholipid hydrolase [EC:3.1.1.5] (A)"	Glycerophospholipid metabolism (ko00564)	[R]	General function prediction only	Cyclic nucleotide-binding domain;; Patatin-like phospholipase	Patatin-like phospholipase domain-containing protein 7 GN=PNPLA7 OS=Homo sapiens (Human) PE=2 SV=3	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: patatin-like phospholipase domain-containing protein 7 [Ailuropoda melanoleuca]
ENSG00000130656(HBZ)	--	0.112175	1	0	0	0	0	0	0	0.108195	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; 	"K13826|2.37746e-99|hsa:3050|HBZ, HBZ-T1, HBZ1; hemoglobin, zeta; K13826 hemoglobin subunit zeta (A)"	--	[C]	Energy production and conversion	Globin	Hemoglobin subunit zeta GN=HBZ OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: hemoglobin subunit zeta [Orycteropus afer afer]
ENSG00000130669(PAK4)	--	64.5687562	3918	53.67689597	3417	63.82671147	4072	55.20846799	3356	57.45356744	3477	59.01922511	3654	0.968809827	-0.254099144	normal	0.990937123	0.003684645	normal	0.985974249	-0.164487847	normal	0.48846016	-0.142027436	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05734|0|hsa:10298|PAK4; p21 protein (Cdc42/Rac)-activated kinase 4 (EC:2.7.11.1); K05734 p21-activated kinase 4 [EC:2.7.11.1] (A)	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Axon guidance (ko04360);; Focal adhesion (ko04510);; T cell receptor signaling pathway (ko04660);; Regulation of actin cytoskeleton (ko04810);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; P21-Rho-binding domain;; Kinase-like	Serine/threonine-protein kinase PAK 4 GN=PAK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase PAK 4 isoformX1 [Canis lupus familiaris] 
ENSG00000130675(MNX1)	--	3.967459468	142	3.297715326	116	3.763037993	139	9.250249233	262	6.932459262	238	7.037395679	232	0.009929938	0.846007869	normal	0.000972503	1.006066996	up	0.091585308	0.724582192	normal	0.000901567	0.861302464	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K08025|1.85181e-91|cjc:100393800|MNX1; motor neuron and pancreas homeobox 1; K08025 homeobox protein HB9 (A)	Maturity onset diabetes of the young (ko04950)	[R]	General function prediction only	Homeobox domain	Motor neuron and pancreas homeobox protein 1 GN=MNX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	"PREDICTED: motor neuron and pancreas homeobox protein 1, partial [Leptonychotes weddellii]"
ENSG00000130684(ZNF337)	--	13.150173	1714	15.921	2129	14.83446	1923	13.97684	1913	14.59207	1969	16.70013	2224	0.980731399	0.12752926	normal	0.981369331	-0.134040358	normal	0.971774744	0.201359216	normal	0.805295518	0.06187075	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:26152|ZNF337; zinc finger protein 337; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; CHY zinc finger;; NTF2 fold immunity protein;; Probable zinc-binding domain;; C2H2-type zinc finger"	Zinc finger protein 337 GN=ZNF337 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 337-like [Tupaia chinensis]
ENSG00000130695(CEP85)	--	36.5828	1301	34.503022	1298	39.54124301	1409	58.05441	1715	47.066952	1446	37.4080342	1250	0.82048613	0.367376459	normal	0.975964915	0.134202421	normal	0.968388774	-0.180828766	normal	0.630512823	0.116206828	normal	--	--	--	"K16766|0|ptr:456656|CEP85, CCDC21; centrosomal protein 85kDa; K16766 centrosomal protein CEP85 (A)"	--	--	--	--	Centrosomal protein of 85 kDa GN=CEP85 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centrosomal protein of 85 kDa isoform X1 [Ailuropoda melanoleuca] 
ENSG00000130699(TAF4)	--	7.6888	588	7.70437	597	7.505932614	602	8.2350512	648	7.895467856	630	6.109001	483	0.968395752	0.109073844	normal	0.971926934	0.056056105	normal	0.864818824	-0.325118004	normal	0.898038535	-0.043108339	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor TFIID complex (GO:0005669);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K03129|0|hsa:6874|TAF4, TAF2C, TAF2C1, TAF4A, TAFII130, TAFII135; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa; K03129 transcription initiation factor TFIID subunit 4 (A)"	Basal transcription factors (ko03022);; Huntington's disease (ko05016);; Herpes simplex infection (ko05168)	[K]	Transcription	Transcription initiation factor TFIID component TAF4 family;; NHR1 homology to TAF	Transcription initiation factor TFIID subunit 4 GN=TAF4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	"PREDICTED: transcription initiation factor TFIID subunit 4, partial [Eptesicus fuscus]"
ENSG00000130700(GATA5)	--	1.813380581	83	1.24167104	60	1.30434926	62	0.441646898	20	0.692927072	32	0.507711262	24	3.22E-06	-2.002244257	down	0.578750844	-0.896864198	normal	0.046135826	-1.323790436	normal	0.001347388	-1.452236547	down	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	K17896|0|pps:100972102|GATA5; GATA binding protein 5; K17896 GATA-binding protein 5 (A)	--	[K]	Transcription	"GATA-type transcription activator, N-terminal;; GATA zinc finger"	Transcription factor GATA-5 GN=GATA5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor GATA-5 [Ceratotherium simum simum]
ENSG00000130701(RBBP8NL)	--	0	0	0	0	0	0	0.0142472	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Tumour-suppressor protein CtIP N-terminal domain	RBBP8 N-terminal-like protein GN=RBBP8NL OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: RBBP8 N-terminal-like protein [Galeopterus variegatus]
ENSG00000130702(LAMA5)	--	94.752371	21723	84.51057	19684	86.505445	20468	84.20996	19161	75.257843	17215	82.444305	18993	0.994675761	-0.211866795	normal	0.993913618	-0.214766139	normal	0.997157441	-0.116184865	normal	0.426227704	-0.181540434	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Biological Process: cell adhesion (GO:0007155);; Biological Process: regulation of cell adhesion (GO:0030155);; Biological Process: regulation of cell migration (GO:0030334);; Biological Process: regulation of embryonic development (GO:0045995);; 	"K06240|0|hsa:3911|LAMA5; laminin, alpha 5; K06240 laminin, alpha 3/5 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin Domain I;; Laminin G domain;; Laminin N-terminal (Domain VI);; Laminin G domain;; Laminin Domain II;; Laminin B (Domain IV);; Concanavalin A-like lectin/glucanases superfamily	Laminin subunit alpha-5 (Precursor) GN=LAMA5 OS=Homo sapiens (Human) PE=1 SV=8	W	Extracellular structures	PREDICTED: laminin subunit alpha-5 [Ceratotherium simum simum]
ENSG00000130703(OSBPL2)	--	8.440833838	480	5.843318013	388	8.329566169	477	7.975525984	509	7.455321	549	7.407917946	540	0.970327952	0.053632272	normal	0.505712793	0.477750388	normal	0.95621792	0.17017134	normal	0.333884706	0.227892098	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Oxysterol-binding protein	Oxysterol-binding protein-related protein 2 GN=OSBPL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 2 [Galeopterus variegatus]
ENSG00000130706(ADRM1)	--	71.3295859	2003	61.76634981	1785	66.39025409	1942	62.50520868	1768	68.2566103	1920	54.976812	1568	0.967732137	-0.210704231	normal	0.983790819	0.083687308	normal	0.905881684	-0.316634127	normal	0.470321832	-0.145962745	normal	--	--	Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; 	--	--	[R]	General function prediction only	Proteasome complex subunit Rpn13 ubiquitin receptor	Proteasomal ubiquitin receptor ADRM1 GN=ADRM1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: proteasomal ubiquitin receptor ADRM1 isoform 1 [Tursiops truncatus] 
ENSG00000130707(ASS1)	--	22.58573349	717	15.87618864	511	15.28564267	479	14.19974965	458	21.9284425	698	21.23052115	679	0.020082567	-0.675629768	normal	0.652536087	0.427391019	normal	0.400494253	0.493778705	normal	0.889614979	0.083992715	normal	[E]	Amino acid transport and metabolism	Molecular Function: argininosuccinate synthase activity (GO:0004055);; Molecular Function: ATP binding (GO:0005524);; Biological Process: arginine biosynthetic process (GO:0006526);; 	"K01940|0|hsa:445|ASS1, ASS, CTLN1; argininosuccinate synthase 1 (EC:6.3.4.5); K01940 argininosuccinate synthase [EC:6.3.4.5] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Arginosuccinate synthase;; Queuosine biosynthesis protein QueC	Argininosuccinate synthase GN=ASS1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: argininosuccinate synthase [Ursus maritimus] 
ENSG00000130711(PRDM12)	--	0.141236	6	0.253094	11	0.0892009	3	0.351246	15	0.249627	10	0.207839	9	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; C2H2 type zinc-finger (2 copies);; SET domain"	PR domain zinc finger protein 12 GN=PRDM12 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: PR domain zinc finger protein 12 [Sus scrofa] 
ENSG00000130713(EXOSC2)	--	22.20052044	914	19.50736213	815	22.93146758	946	20.75630296	857	22.02554239	899	15.12683291	621	0.971417193	-0.123516739	normal	0.970948779	0.11988264	normal	0.055077839	-0.614317091	normal	0.458762106	-0.192204494	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; 	K03679|0|pps:100994305|EXOSC2; exosome component 2; K03679 exosome complex component RRP4 (A)	RNA degradation (ko03018)	[A]	RNA processing and modification	Exosome complex exonuclease RRP4 N-terminal region	Exosome complex component RRP4 GN=EXOSC2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component RRP4 [Ceratotherium simum simum]
ENSG00000130714(POMT1)	--	12.02941359	572	11.76891354	552	11.37940318	552	12.28020015	572	11.75377977	564	12.5948817	600	0.97272563	-0.030749668	normal	0.972190819	0.009574388	normal	0.967401653	0.111709172	normal	0.935206041	0.029664631	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: mannosyltransferase activity (GO:0000030);; Biological Process: protein O-linked glycosylation (GO:0006493);; Cellular Component: membrane (GO:0016020);; 	K00728|0|mcf:102140167|POMT1; protein-O-mannosyltransferase 1; K00728 dolichyl-phosphate-mannose-protein mannosyltransferase [EC:2.4.1.109] (A)	Other types of O-glycan biosynthesis (ko00514)	[O]	"Posttranslational modification, protein turnover, chaperones"	Dolichyl-phosphate-mannose-protein mannosyltransferase;; MIR domain	Protein O-mannosyl-transferase 1 GN=POMT1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein O-mannosyl-transferase 1 isoform 1 [Ceratotherium simum simum]
ENSG00000130717(UCK1)	--	11.669803	501	11.158088	492	12.348123	546	12.745008	556	14.80592812	633	11.972056	520	0.965383416	0.119095228	normal	0.845459001	0.3411939	normal	0.969694785	-0.078458067	normal	0.624874209	0.130040872	normal	[F]	Nucleotide transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Biological Process: metabolic process (GO:0008152);; Molecular Function: kinase activity (GO:0016301);; 	K00876|0|nle:100583889|UCK1; uridine-cytidine kinase 1; K00876 uridine kinase [EC:2.7.1.48] (A)	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Phosphoribulokinase / Uridine kinase family	Uridine-cytidine kinase 1 GN=UCK1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: uridine-cytidine kinase 1 isoform 1 [Ceratotherium simum simum]
ENSG00000130720(FIBCD1)	--	3.97244408	221	2.844375524	156	4.285713772	171	2.95938424	166	4.141922225	236	4.279550474	179	0.769259731	-0.440151042	normal	0.438132246	0.57128228	normal	0.966114095	0.057177553	normal	0.903211684	0.063449185	normal	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Fibrinogen C domain-containing protein 1 GN=FIBCD1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: fibrinogen C domain-containing protein 1 [Sus scrofa]
ENSG00000130723(PRRC2B)	--	38.76157955	6882	39.722813	7679	40.98205178	7493	39.61945173	6530	34.41917121	6391	43.39554482	8207	0.993431696	-0.106552738	normal	0.972975288	-0.286241427	normal	0.993695668	0.122996333	normal	0.739291315	-0.082381379	normal	--	--	--	--	--	[X]	--	BAT2 N-terminus	Protein PRRC2B GN=PRRC2B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein PRRC2B [Ceratotherium simum simum]
ENSG00000130724(CHMP2A)	--	119.26152	1860	123.56954	1932	108.52207	1753	104.7976	1662	113.58314	1717	105.1826	1603	0.970648688	-0.193045687	normal	0.971494741	-0.191472517	normal	0.978773837	-0.137219175	normal	0.356515721	-0.175876867	normal	[N]	Cell motility	Biological Process: vacuolar transport (GO:0007034);; 	K12191|6.42672e-69|umr:103677215|CHMP2A; charged multivesicular body protein 2A; K12191 charged multivesicular body protein 2A (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snf7	Charged multivesicular body protein 2a GN=CHMP2A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 2a isoform X3 [Myotis lucifugus]
ENSG00000130725(UBE2M)	--	103.714699	2706	99.557598	2730	101.736623	2849	100.87277	2686	93.46454	2477	95.0361	2522	0.989054421	-0.041511141	normal	0.981495402	-0.161639591	normal	0.979119488	-0.184074867	normal	0.533230455	-0.129778246	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10579|4.89621e-133|rno:361509|Ube2m; ubiquitin-conjugating enzyme E2M (EC:6.3.2.19); K10579 ubiquitin-conjugating enzyme E2 M [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	NEDD8-conjugating enzyme Ubc12 GN=UBE2M OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NEDD8-conjugating enzyme Ubc12 [Erinaceus europaeus]
ENSG00000130726(TRIM28)	--	212.6232049	11940	221.9062658	12710	227.987949	13013	227.390263	12596	216.815155	12118	203.479906	11222	0.996712453	0.046324759	normal	0.996145597	-0.090227981	normal	0.990900618	-0.221887426	normal	0.731740104	-0.089159291	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	"K08882|0|hsa:10155|TRIM28, KAP1, PPP1R157, RNF96, TF1B, TIF1B; tripartite motif containing 28; K08882 tripartite motif-containing protein 28 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	B-box zinc finger;; zinc-RING finger domain;; PHD-finger	Transcription intermediary factor 1-beta GN=TRIM28 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: transcription intermediary factor 1-beta isoform 1 [Odobenus rosmarus divergens]
ENSG00000130731(METTL26)	--	65.22151996	567	55.22205445	506	58.64648903	521	65.62740443	595	61.182572	563	55.463538	498	0.972650798	0.038606546	normal	0.963081341	0.132196296	normal	0.969598687	-0.073211689	normal	0.923805752	0.033316216	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF938);; Methyltransferase domain;; Protein of unknown function (DUF938)	UPF0585 protein C16orf13 GN=C16orf13 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0585 protein C16orf13 homolog isoform X2 [Myotis lucifugus]
ENSG00000130733(YIPF2)	--	13.74801699	475	11.65712749	427	13.52949169	482	19.62997019	675	21.49642926	703	17.91033019	585	0.473623574	0.47483352	normal	0.016568182	0.695922539	normal	0.915510617	0.270340993	normal	0.008176935	0.48280897	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Yip1 domain	Protein YIPF2 GN=YIPF2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein YIPF2 isoform X1 [Pteropus alecto] 
ENSG00000130734(ATG4D)	--	6.582077	179	8.083744803	192	5.608343291	151	7.703316	227	6.570838	182	6.41405967	196	0.906848248	0.309536665	normal	0.962272065	-0.097803061	normal	0.877562502	0.364798333	normal	0.622132343	0.190787698	normal	--	--	--	"K08342|0|ptr:455708|ATG4D; autophagy related 4D, cysteine peptidase; K08342 cysteine protease ATG4 [EC:3.4.22.-] (A)"	Regulation of autophagy (ko04140)	[ZU]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	Peptidase family C54	"Cysteine protease ATG4D, mitochondrial GN=ATG4D OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cysteine protease ATG4D isoform 1 [Canis lupus familiaris]
ENSG00000130741(EIF2S3)	--	114.116717	5336	116.8360029	5477	113.446349	5234	126.6640017	5970	117.2580021	5486	117.2170015	5501	0.991481926	0.131104301	normal	0.993630462	-0.01905256	normal	0.993225154	0.063470647	normal	0.824779183	0.058054004	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K03242|0|pps:100994055|EIF2S3; eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa; K03242 translation initiation factor 2 subunit 3 (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	"Elongation factor Tu GTP binding domain;; Initiation factor eIF2 gamma, C terminal;; Elongation factor Tu domain 2"	Eukaryotic translation initiation factor 2 subunit 3 GN=EIF2S3 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 2 subunit 3 [Galeopterus variegatus]
ENSG00000130748(TMEM160)	--	76.6654	500	66.2691	457	71.967	497	71.5371	485	79.6095	521	71.9563	477	0.969042888	-0.074543016	normal	0.955723442	0.16714435	normal	0.969529022	-0.067338857	normal	0.988196733	0.007384517	normal	--	--	--	--	--	--	--	--	Transmembrane protein 160 GN=TMEM160 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 160 [Eptesicus fuscus]
ENSG00000130749(ZC3H4)	--	9.62322806	1332	10.31131504	1465	8.865444015	1266	9.21519023	1284	9.593682565	1333	10.04441039	1390	0.980148819	-0.083682818	normal	0.973141265	-0.15747994	normal	0.976799555	0.126371925	normal	0.883063834	-0.041162128	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[A]	RNA processing and modification	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 4 GN=ZC3H4 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	"PREDICTED: zinc finger CCCH domain-containing protein 4-like, partial [Leptonychotes weddellii]"
ENSG00000130751(NPAS1)	--	4.67095667	111	3.228265429	85	3.912204456	96	2.097120796	56	3.283428382	81	4.753494687	131	0.04408748	-0.99805405	normal	0.969935056	-0.089339014	normal	0.867741502	0.434290375	normal	0.85721208	-0.142407167	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09098|0|hsa:4861|NPAS1, MOP5, PASD5, bHLHe11; neuronal PAS domain protein 1; K09098 neuronal PAS domain-containing protein 1/3 (A)"	--	[TK]	Signal transduction mechanisms;; Transcription	PAS fold;; PAS domain;; PAS fold;; Helix-loop-helix DNA-binding domain	Neuronal PAS domain-containing protein 1 GN=NPAS1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: neuronal PAS domain-containing protein 1 isoform X1 [Mustela putorius furo] 
ENSG00000130755(GMFG)	--	0	0	0	0	0.319286806	0	0.205437172	2	0.2863862	1	1.686896326	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	--	--	[W]	Extracellular structures	Cofilin/tropomyosin-type actin-binding protein	Glia maturation factor gamma GN=GMFG OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: glia maturation factor gamma isoform X1 [Tupaia chinensis] 
ENSG00000130758(MAP3K10)	--	16.465323	1004	15.598881	1073	17.728677	1060	17.31859	969	14.859168	889	19.681524	1233	0.976761887	-0.08189538	normal	0.910124489	-0.292367844	normal	0.958179102	0.209539667	normal	0.900137412	-0.041793153	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04418|0|hsa:4294|MAP3K10, MEKK10, MLK2, MST; mitogen-activated protein kinase kinase kinase 10 (EC:2.7.11.25); K04418 mitogen-activated protein kinase kinase kinase 10 [EC:2.7.11.25] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Mitogen-activated protein kinase kinase kinase 10 GN=MAP3K10 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 10 [Lipotes vexillifer]
ENSG00000130762(ARHGEF16)	--	3.989484619	215	2.449132612	164	2.65500075	178	3.083854899	179	3.516221715	208	3.016519883	197	0.917049041	-0.292911398	normal	0.903880102	0.318845185	normal	0.959772285	0.136920776	normal	0.92943707	0.047386906	normal	[T]	Signal transduction mechanisms	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Variant SH3 domain;; SH3 domain;; PH domain	Rho guanine nucleotide exchange factor 16 GN=ARHGEF16 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 16 [Galeopterus variegatus]
ENSG00000130764(LRRC47)	--	10.47354834	877	9.861826337	844	9.870932301	842	10.07698135	844	11.39610411	947	10.02986433	840	0.97473134	-0.086012484	normal	0.968239207	0.144450426	normal	0.977558435	-0.011701306	normal	0.963874332	0.016608206	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: phenylalanine-tRNA ligase activity (GO:0004826);; Molecular Function: protein binding (GO:0005515);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; B3/4 domain	Leucine-rich repeat-containing protein 47 GN=LRRC47 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: leucine-rich repeat-containing protein 47 [Chrysochloris asiatica]
ENSG00000130766(SESN2)	--	5.264849	343	7.949451	524	5.122263	339	5.794061	375	7.596043	490	10.175045	664	0.96444387	0.097432286	normal	0.964464395	-0.11785978	normal	2.32E-05	0.958494832	normal	0.579806989	0.322361614	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of response to reactive oxygen species (GO:1901031);; 	"K10141|0|hsa:83667|SESN2, HI95, SES2, SEST2; sestrin 2; K10141 sestrin (A)"	p53 signaling pathway (ko04115)	[S]	Function unknown	PA26 p53-induced protein (sestrin)	Sestrin-2 GN=SESN2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: sestrin-2 isoform X2 [Lipotes vexillifer]
ENSG00000130768(SMPDL3B)	--	2.285797269	81	3.303460954	116	1.944962117	72	0.54977182	20	0.998821895	35	1.061564968	39	6.56E-06	-1.967695337	down	2.59E-06	-1.707202613	down	0.490614273	-0.867677256	normal	0.000356596	-1.536729898	down	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	"K01128|0|ptr:456681|SMPDL3B; sphingomyelin phosphodiesterase, acid-like 3B; K01128 [EC:3.1.4.-] (A)"	--	[I]	Lipid transport and metabolism	Calcineurin-like phosphoesterase	Acid sphingomyelinase-like phosphodiesterase 3b (Precursor) GN=SMPDL3B OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: acid sphingomyelinase-like phosphodiesterase 3b [Dasypus novemcinctus]
ENSG00000130770(ATPIF1)	--	109.58202	656	108.508776	709	115.855999	753	118.490972	766	112.3815	672	99.799036	659	0.954630852	0.192399002	normal	0.970336734	-0.098535033	normal	0.952391345	-0.200232636	normal	0.910252232	-0.035893986	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; Biological Process: negative regulation of ATPase activity (GO:0032780);; Molecular Function: ATPase inhibitor activity (GO:0042030);; 	--	--	--	--	"Mitochondrial ATPase inhibitor, IATP"	"ATPase inhibitor, mitochondrial (Precursor) GN=ATPIF1 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: ATPase inhibitor, mitochondrial [Chrysochloris asiatica]"
ENSG00000130772(MED18)	--	11.59346	310	9.518690816	282	10.555838	278	10.319319	301	9.533453	276	9.5797	253	0.965551298	-0.072969939	normal	0.965342465	-0.052170644	normal	0.957831177	-0.143420775	normal	0.815138112	-0.089711457	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15135|1.07688e-142|ptr:456683|MED18; mediator complex subunit 18; K15135 mediator of RNA polymerase II transcription subunit 18 (A)	--	[S]	Function unknown	Med18 protein	Mediator of RNA polymerase II transcription subunit 18 GN=MED18 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 18 [Pteropus alecto] 
ENSG00000130775(THEMIS2)	--	1.632908928	54	0.311850124	17	0.735125706	36	0.406240099	14	0.95401056	29	0.42932829	14	0.001455504	-1.866658066	down	0.955015474	0.700886836	normal	0.509245699	-1.281671927	normal	0.354030185	-0.929125833	normal	--	--	--	--	--	--	--	"Cell-cycle sustaining, positive selection,"	Protein THEMIS2 GN=THEMIS2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein THEMIS2 isoform X1 [Galeopterus variegatus]
ENSG00000130779(CLIP1)	--	18.08770904	2383	21.62863492	2935	19.4397167	2678	22.89140448	3123	19.68310803	2626	22.74979932	3037	0.874039006	0.35911858	normal	0.979787847	-0.181821038	normal	0.981494349	0.173107655	normal	0.592181881	0.11454586	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	"K10421|0|hsa:6249|CLIP1, CLIP, CLIP-170, CLIP170, CYLN1, RSN; CAP-GLY domain containing linker protein 1; K10421 CAP-Gly domain-containing linker protein 1 (A)"	--	[ZR]	Cytoskeleton;; General function prediction only	CAP-Gly domain	CAP-Gly domain-containing linker protein 1 GN=CLIP1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: CAP-Gly domain-containing linker protein 1 isoform X2 [Camelus bactrianus]
ENSG00000130783(CCDC62)	--	0.121787079	8	0.209685934	12	0.157023096	9	0.138322442	9	0.059798589	3	0.020947506	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 62 GN=CCDC62 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 62 [Odobenus rosmarus divergens]
ENSG00000130787(HIP1R)	--	6.2643305	637	4.976494687	521	6.14012	590	7.191983	700	7.1919479	724	7.131482	709	0.969802482	0.104987675	normal	0.567373839	0.452161862	normal	0.926662879	0.256179442	normal	0.189197087	0.266122111	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: phospholipid binding (GO:0005543);; 	--	--	[Z]	Cytoskeleton	ANTH domain;; I/LWEQ domain;; ENTH domain	Huntingtin-interacting protein 1-related protein GN=HIP1R OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: huntingtin-interacting protein 1-related protein [Sus scrofa]
ENSG00000130803(ZNF317)	--	8.666	689	10.52658	676	9.137608	696	6.96097	556	8.039747	632	9.33776	661	0.844471856	-0.339406908	normal	0.96749226	-0.118251581	normal	0.972142045	-0.08254441	normal	0.435176531	-0.177205287	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100988083|ZNF317; zinc finger protein 317; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; C2H2 type zinc-finger (2 copies)"	Zinc finger protein 317 GN=ZNF317 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 317 [Galeopterus variegatus] 
ENSG00000130810(PPAN)	--	17.75346706	986	18.0508678	960	18.65529953	996	17.80621269	932	20.66478202	1205	17.72776448	1104	0.973831602	-0.11191055	normal	0.900558256	0.306069128	normal	0.971751519	0.140029057	normal	0.600318914	0.119077249	normal	--	--	--	"K14859|0|hsa:56342|PPAN, BXDC3, SSF, SSF-1, SSF1, SSF2; peter pan homolog (Drosophila); K14859 ribosome biogenesis protein SSF1/2 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Brix domain	Suppressor of SWI4 1 homolog GN=PPAN OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: suppressor of SWI4 1 homolog isoform X2 [Mustela putorius furo]
ENSG00000130811(EIF3G)	--	60.509261	1364	65.70402919	1464	56.69311	1314	66.597876	1529	71.28272701	1594	60.846246	1395	0.977072907	0.133770133	normal	0.980487911	0.101209306	normal	0.98094792	0.077921357	normal	0.640572455	0.103799067	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K03248|0|ptr:745388|EIF3G, EIF3S4; eukaryotic translation initiation factor 3, subunit G; K03248 translation initiation factor 3 subunit G (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	"Eukaryotic translation initiation factor 3 subunit G;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Eukaryotic translation initiation factor 3 subunit G {ECO:0000255|HAMAP-Rule:MF_03006} OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	eukaryotic translation initiation factor 3 subunit G [Bos taurus] 
ENSG00000130812(ANGPTL6)	--	1.208542796	30	0.754599663	19	0.700036674	18	0.951914473	23	1.207300054	29	1.070599121	27	0.978875131	-0.391209356	normal	0.969600721	0.552796263	normal	0.974476459	0.539450619	normal	0.830963033	0.216629199	normal	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-related protein 6 (Precursor) GN=ANGPTL6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: angiopoietin-related protein 6 isoform X1 [Mustela putorius furo]
ENSG00000130813(C19orf66)	--	4.0727874	181	3.141409	145	4.9826033	216	5.1466728	198	4.495241684	162	4.54364	188	0.963500455	0.097883913	normal	0.959889791	0.137160494	normal	0.947074172	-0.207035046	normal	0.999504621	-0.004986356	normal	--	--	--	--	--	--	--	Uncharacterised protein UPF0515	UPF0515 protein C19orf66 GN=C19orf66 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0515 protein C19orf66 homolog [Galeopterus variegatus]
ENSG00000130816(DNMT1)	--	25.12838928	3320	26.69771954	3563	27.48711736	3663	23.34072	3108	22.57288199	3022	27.23079815	2967	0.987218273	-0.125968732	normal	0.965336912	-0.258895906	normal	0.936794661	-0.312168736	normal	0.181038759	-0.234464085	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: chromatin binding (GO:0003682);; Molecular Function: zinc ion binding (GO:0008270);; 	"K00558|0|hsa:1786|DNMT1, ADCADN, AIM, CXXC9, DNMT, HSN1E, MCMT; DNA (cytosine-5-)-methyltransferase 1 (EC:2.1.1.37); K00558 DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37] (A)"	Cysteine and methionine metabolism (ko00270);; MicroRNAs in cancer (ko05206)	--	--	C-5 cytosine-specific DNA methylase;; BAH domain;; Cytosine specific DNA methyltransferase replication foci domain;; DMAP1-binding Domain;; CXXC zinc finger domain	DNA (cytosine-5)-methyltransferase 1 GN=DNMT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA (cytosine-5)-methyltransferase 1 isoform X1 [Loxodonta africana]
ENSG00000130818(ZNF426)	--	0.128686742	17	0.191145069	18	0.166551803	14	0.819489412	93	1.2478636	99	0.983892683	111	2.07E-08	2.321200461	up	5.39E-09	2.344482067	up	5.27E-13	2.850767627	up	2.24E-10	2.607412956	up	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100987402|ZNF426; zinc finger protein 426; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; NTF2 fold immunity protein"	Zinc finger protein 426 GN=ZNF426 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 426-like [Galeopterus variegatus]
ENSG00000130821(SLC6A8)	--	9.088149	452	7.946698143	322	6.574990134	333	8.781221339	411	10.61694054	566	5.386884001	278	0.95515113	-0.167419522	normal	0.003265793	0.789483185	normal	0.919306708	-0.267397769	normal	0.821227919	0.158951546	normal	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05039|0|rno:50690|Slc6a8, CHOT1, CHT1, CRT, CT1; solute carrier family 6 (neurotransmitter transporter), member 8; K05039 solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium- and chloride-dependent creatine transporter 1 GN=SLC6A8 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium- and chloride-dependent creatine transporter 1 isoform 1 [Ceratotherium simum simum]
ENSG00000130822(PNCK)	--	0.07304884	2	0	0	0	0	0	0	0.094434088	0	0.036088565	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08795|0|hsa:139728|PNCK, BSTK3, CaMK1b; pregnancy up-regulated nonubiquitous CaM kinase (EC:2.7.11.17); K08795 pregnancy upregulated non-ubiquitously expressed CaM kinase [EC:2.7.11.17] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Calcium/calmodulin-dependent protein kinase type 1B GN=PNCK OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type 1B isoform X1 [Leptonychotes weddellii] 
ENSG00000130826(DKC1)	--	50.74429126	2678	48.78816531	2666	49.64886123	2606	52.05042417	2794	54.53422314	2847	41.01588329	2182	0.989342686	0.030326763	normal	0.988108993	0.073298916	normal	0.954566753	-0.264309568	normal	0.867977277	-0.045109821	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; 	K11131|0|ggo:101149886|DKC1; H/ACA ribonucleoprotein complex subunit 4; K11131 H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[J]	"Translation, ribosomal structure and biogenesis"	DKCLD (NUC011) domain;; TruB family pseudouridylate synthase (N terminal domain);; PUA domain	H/ACA ribonucleoprotein complex subunit 4 GN=DKC1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: H/ACA ribonucleoprotein complex subunit 4 isoform X1 [Oryctolagus cuniculus]
ENSG00000130827(PLXNA3)	--	2.5505319	561	1.545357	343	2.296074	512	2.80262	613	2.721618	595	2.222772	490	0.96906788	0.096800381	normal	0.004435482	0.770644041	normal	0.969547236	-0.071437792	normal	0.490810223	0.240529198	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06820|0|hsa:55558|PLXNA3, 6.3, HSSEXGENE, PLXN3, PLXN4, XAP-6; plexin A3; K06820 plexin A (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; Sema domain;; IPT/TIG domain;; Plexin repeat	Plexin-A3 (Precursor) GN=PLXNA3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: plexin-A3 [Eptesicus fuscus]
ENSG00000130829(DUSP9)	--	1.01030442	39	0.695026808	28	0.633684599	25	0.5902165	23	0.853832317	33	0.185156512	7	0.909484039	-0.753575363	normal	0.9813864	0.205386206	normal	0.502873889	-1.646360853	normal	0.497728887	-0.569789963	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18498|0|hsa:1852|DUSP9, MKP-4, MKP4; dual specificity phosphatase 9 (EC:3.1.3.16 3.1.3.48); K18498 dual specificity phosphatase 9 [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain"	Dual specificity protein phosphatase 9 GN=DUSP9 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 9 [Oryctolagus cuniculus]
ENSG00000130830(MPP1)	--	9.334683073	370	8.812568676	337	10.09130653	372	5.210346	202	4.173344484	161	4.760141227	178	0.000835075	-0.898868624	normal	2.82E-05	-1.079938394	down	1.88E-05	-1.065312833	down	1.86E-06	-1.017554391	down	[F]	Nucleotide transport and metabolism	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Guanylate kinase;; PDZ domain (Also known as DHR or GLGF);; Variant SH3 domain;; SH3 domain	55 kDa erythrocyte membrane protein GN=MPP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	55 kDa erythrocyte membrane protein [Oryctolagus cuniculus] 
ENSG00000130844(ZNF331)	--	13.92955986	789	15.22726316	804	16.47574111	892	7.602402244	499	5.96703009	391	14.69782884	695	0.012960791	-0.690111801	normal	8.05E-07	-1.058533943	down	0.796866805	-0.367614189	normal	0.006917859	-0.668805868	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:55422|ZNF331, RITA, ZNF361, ZNF463; zinc finger protein 331; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain"	Zinc finger protein 331 GN=ZNF331 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	zinc finger protein 331 [Canis lupus familiaris] 
ENSG00000130856(ZNF236)	--	3.245715582	509	2.851829192	450	2.2356989	377	2.482831336	380	3.19833599	529	3.088952828	519	0.591847039	-0.450916838	normal	0.943441037	0.211260779	normal	0.591941305	0.451329252	normal	0.86133369	0.075482415	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 236 GN=ZNF236 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 236 [Ceratotherium simum simum]
ENSG00000130876(SLC7A10)	--	0.100834	3	0	0	0	0	0.16718	5	0.0650596	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13782|0|ggo:101145946|SLC7A10; asc-type amino acid transporter 1; K13782 solute carrier family 7 (L-type amino acid transporter), member 10 (A)"	--	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease	Asc-type amino acid transporter 1 GN=SLC7A10 OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: asc-type amino acid transporter 1 [Pteropus alecto]
ENSG00000130881(LRP3)	--	34.062493	2428	33.73742	2471	32.898966	2459	38.97885	2803	41.80962853	2993	39.954587	2889	0.979869795	0.176267185	normal	0.962295528	0.254928766	normal	0.971073879	0.224079759	normal	0.220078859	0.218146892	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; CUB domain	Low-density lipoprotein receptor-related protein 3 (Precursor) GN=LRP3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 3 isoform X1 [Sus scrofa]
ENSG00000130921(C12orf65)	--	9.748444	397	8.061976	353	9.496729	417	9.574969	400	10.716658	422	10.85599	453	0.969488897	-0.019894567	normal	0.93271954	0.23522559	normal	0.96461967	0.110786649	normal	0.73222535	0.10710082	normal	--	--	Molecular Function: translation release factor activity (GO:0003747);; Biological Process: translational termination (GO:0006415);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	RF-1 domain	"Probable peptide chain release factor C12orf65, mitochondrial (Precursor) GN=C12orf65 OS=Homo sapiens (Human) PE=2 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable peptide chain release factor C12orf65 homolog, mitochondrial [Galeopterus variegatus]"
ENSG00000130935(NOL11)	--	30.6197296	1494	31.35368098	1568	31.12720098	1544	32.89550083	1690	33.1116378	1680	27.53686606	1399	0.976820353	0.146868766	normal	0.982619008	0.078036397	normal	0.975275411	-0.150413392	normal	0.918339744	0.028475834	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	--	--	--	--	NUC205 domain	Nucleolar protein 11 GN=NOL11 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nucleolar protein 11 [Galeopterus variegatus]
ENSG00000130939(UBE4B)	--	10.0432573	1027	11.97683008	1261	11.836265	1198	10.83739171	1098	9.463525519	1003	11.95274315	1267	0.97863936	0.065514813	normal	0.843320363	-0.351199813	normal	0.980133467	0.072408285	normal	0.791269698	-0.070443763	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Cellular Component: ubiquitin ligase complex (GO:0000151);; Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: ubiquitin-ubiquitin ligase activity (GO:0034450);; 	"K10597|0|hsa:10277|UBE4B, E4, HDNB1, UBOX3, UFD2, UFD2A; ubiquitination factor E4B; K10597 ubiquitin conjugation factor E4 B [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin elongating factor core;; U-box domain	Ubiquitin conjugation factor E4 B {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin conjugation factor E4 B isoform X2 [Equus caballus]
ENSG00000130940(CASZ1)	--	0.470444371	54	0.21861832	34	0.392701437	42	1.247965096	146	0.605779	68	1.055276883	123	4.33E-05	1.379318898	up	0.396077219	0.948212458	normal	2.71E-05	1.508696332	up	0.017094891	1.352146134	normal	--	--	--	--	--	[R]	General function prediction only	--	Zinc finger protein castor homolog 1 GN=CASZ1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: zinc finger protein castor homolog 1 [Orcinus orca]
ENSG00000130943(PKDREJ)	--	0.0772493	10	0.0691843	9	0.122549	15	0.0308693	4	0.0748218	9	0.0767231	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Polycystin cation channel;; REJ domain;; PLAT/LH2 domain;; Ion transport protein	Polycystic kidney disease and receptor for egg jelly-related protein (Precursor) GN=PKDREJ OS=Homo sapiens (Human) PE=2 SV=2	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: polycystic kidney disease and receptor for egg jelly-related protein [Galeopterus variegatus]
ENSG00000130948(HSD17B3)	--	0.236590195	4	0	0	0	0	0	0	0.068354283	0	0.0579769	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K10207|0|hsa:3293|HSD17B3, EDH17B3, SDR12C2; hydroxysteroid (17-beta) dehydrogenase 3 (EC:1.1.1.64); K10207 testosterone 17beta-dehydrogenase (NADP+) [EC:1.1.1.64] (A)"	Steroid hormone biosynthesis (ko00140)	[I]	Lipid transport and metabolism	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase	Testosterone 17-beta-dehydrogenase 3 GN=HSD17B3 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: testosterone 17-beta-dehydrogenase 3-like [Physeter catodon]
ENSG00000130950(NUTM2F)	--	0.018529477	1	0	0	0	0	0	0	0.018075895	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	NUT protein N terminus;; NUT protein C terminal	NUT family member 2F GN=NUTM2F OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: NUT family member 2G-like [Equus caballus]
ENSG00000130956(HABP4)	--	14.15306591	758	15.16022773	819	15.38650214	850	10.2362193	561	10.85949479	572	11.4543165	617	0.500596948	-0.463931575	normal	0.23704053	-0.538079104	normal	0.473246651	-0.469499034	normal	0.003634522	-0.492604731	normal	--	--	--	--	--	[R]	General function prediction only	Hyaluronan / mRNA binding family	Intracellular hyaluronan-binding protein 4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: intracellular hyaluronan-binding protein 4 [Odobenus rosmarus divergens]
ENSG00000130957(FBP2)	--	0.0443761	1	0.0865481	2	0	0	0	0	0	0	0.307367	7	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	--	"K03841|0|hsa:8789|FBP2; fructose-1,6-bisphosphatase 2 (EC:3.1.3.11); K03841 fructose-1,6-bisphosphatase I [EC:3.1.3.11] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Carbon metabolism (ko01200);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Fructose-1-6-bisphosphatase;; Inositol monophosphatase family	"Fructose-1,6-bisphosphatase isozyme 2 GN=FBP2 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: fructose-1,6-bisphosphatase isozyme 2 [Equus caballus]"
ENSG00000130958(SLC35D2)	--	17.636024	367	14.9240504	319	15.329901	312	18.20826796	392	15.821176	335	15.573214	323	0.967425333	0.063982136	normal	0.966316059	0.048951653	normal	0.96743815	0.041498994	normal	0.895327936	0.051322052	normal	--	--	--	"K15281|0|ptr:742164|SLC35D2; solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2; K15281 solute carrier family 35 (A)"	--	[GOU]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Triose-phosphate Transporter family;; UAA transporter family	UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter GN=SLC35D2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter [Odobenus rosmarus divergens]
ENSG00000130962(PRRG1)	--	15.20705478	707	14.4425452	704	14.11938761	654	7.97762879	492	8.204958168	488	7.580365002	466	0.191002215	-0.552436251	normal	0.219726087	-0.54869663	normal	0.396200864	-0.495887007	normal	0.002370913	-0.535547309	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain	Transmembrane gamma-carboxyglutamic acid protein 1 (Precursor) GN=PRRG1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: transmembrane gamma-carboxyglutamic acid protein 1-like [Sus scrofa]
ENSG00000130985(UBA1)	--	114.4523108	7945	110.4178441	7719	116.0820041	8072	117.865085	8160	118.8793777	8175	111.1234291	7706	0.995537144	0.007688202	normal	0.994927238	0.061366532	normal	0.994857187	-0.075221006	normal	0.996314771	-0.002862296	normal	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	"K03178|0|hsa:7317|UBA1, A1S9, A1S9T, A1ST, AMCX1, CFAP124, GXP1, POC20, SMAX2, UBA1A, UBE1, UBE1X; ubiquitin-like modifier activating enzyme 1 (EC:6.3.2.19); K03178 ubiquitin-activating enzyme E1 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	ThiF family;; Ubiquitin-activating enzyme e1 C-terminal domain;; Repeat in ubiquitin-activating (UBA) protein;; Ubiquitin-activating enzyme active site	Ubiquitin-like modifier-activating enzyme 1 GN=UBA1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like modifier-activating enzyme 1 isoform X1 [Tupaia chinensis]
ENSG00000130988(RGN)	--	0.042865321	1	0.027109335	1	0	0	0.042569369	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	--	K01053|0|ggo:101127283|RGN; regucalcin isoform 1; K01053 gluconolactonase [EC:3.1.1.17] (A)	Pentose phosphate pathway (ko00030);; Ascorbate and aldarate metabolism (ko00053);; Carbon metabolism (ko01200);; Degradation of aromatic compounds (ko01220)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	SMP-30/Gluconolaconase/LRE-like region	Regucalcin GN=RGN OS=Homo sapiens (Human) PE=1 SV=1	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: regucalcin isoform X1 [Galeopterus variegatus]
ENSG00000130997(POLN)	--	5.456076121	340	7.328092971	386	6.38575709	349	6.196771589	333	4.515953481	267	6.390672365	352	0.966815874	-0.060568255	normal	0.325807257	-0.550578356	normal	0.968794591	0.004039521	normal	0.496589897	-0.196520078	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Biological Process: DNA replication (GO:0006260);; 	"K16618|0|hsa:353497|POLN, POL4P; polymerase (DNA directed) nu (EC:2.7.7.7); K16618 DNA polymerase nu [EC:2.7.7.7] (A)"	Fanconi anemia pathway (ko03460)	[R]	General function prediction only	DNA polymerase family A	DNA polymerase nu GN=POLN OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: DNA polymerase nu [Ceratotherium simum simum]
ENSG00000131013(PPIL4)	--	6.452345	286	7.827557439	342	8.14548007	355	8.829237627	397	8.573551862	374	7.75610402	341	0.66594009	0.440276328	normal	0.962572436	0.10716216	normal	0.966806333	-0.066051608	normal	0.604435796	0.156441984	normal	[R]	General function prediction only	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	K12735|0|cjc:100415209|PPIL4; peptidylprolyl isomerase (cyclophilin)-like 4; K12735 peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Peptidyl-prolyl cis-trans isomerase-like 4 GN=PPIL4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase-like 4 isoform 1 [Dasypus novemcinctus]
ENSG00000131015(ULBP2)	--	2.02936143	46	0.486623206	11	0.974625	21	4.779994	107	3.447012722	78	2.949926	67	0.009529089	1.160957342	up	1.22E-08	2.647904598	up	0.002579795	1.597728633	up	0.001094944	1.668950333	up	--	--	--	"K07986|6.09543e-161|hsa:80328|ULBP2, ALCAN-alpha, N2DL2, NKG2DL2, RAET1H; UL16 binding protein 2; K07986 UL16 binding protein (A)"	Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2"	NKG2D ligand 2 (Precursor) GN=ULBP2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: retinoic acid early transcript 1L protein-like [Tupaia chinensis]
ENSG00000131016(AKAP12)	--	64.09416	12726	58.4616464	11607	58.7852921	11682	26.494642	5220	20.35085652	3962	15.47970684	3039	8.02E-14	-1.316232768	down	0	-1.571752812	down	0	-1.950376559	down	6.99E-29	-1.582130107	down	--	--	Biological Process: protein targeting (GO:0006605);; Biological Process: signal transduction (GO:0007165);; 	"K16528|0|hsa:9590|AKAP12, AKAP250, SSeCKS; A kinase (PRKA) anchor protein 12; K16528 A-kinase anchor protein 12 (A)"	--	--	--	WSK motif;; RII binding domain	A-kinase anchor protein 12 GN=AKAP12 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 12 isoform X1 [Galeopterus variegatus]
ENSG00000131018(SYNE1)	--	3.420710524	934	3.293677872	1073	4.996581373	1391	7.082466401	1870	5.39455048	1392	7.721172077	2098	1.35E-06	0.969563064	normal	0.842923917	0.353643888	normal	0.081945409	0.58408022	normal	0.04726856	0.637174185	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Nuclear envelope localisation domain;; CAMSAP CH domain	Nesprin-1 GN=SYNE1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: nesprin-1 [Canis lupus familiaris]
ENSG00000131019(ULBP3)	--	2.24360793	39	1.968798857	35	1.878261989	33	2.0912758	37	3.210037	49	1.658831	26	0.981761974	-0.102629359	normal	0.954762111	0.447590227	normal	0.978576762	-0.334915899	normal	0.977448148	0.043859065	normal	--	--	--	"K07986|0|hsa:79465|ULBP3, RAET1N; UL16 binding protein 3; K07986 UL16 binding protein (A)"	Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2"	NKG2D ligand 3 (Precursor) GN=ULBP3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: NKG2D ligand 1-like [Equus caballus]
ENSG00000131023(LATS1)	--	4.365870895	503	5.345689941	635	4.426004	514	5.177732911	584	5.054517349	587	5.463283159	644	0.953324681	0.184055604	normal	0.96439297	-0.134489402	normal	0.875427304	0.316168174	normal	0.669976203	0.114623043	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08791|0|ggo:101129682|LATS1; serine/threonine-protein kinase LATS1; K08791 serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1] (A)	Hippo signaling pathway (ko04390)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; UBA/TS-N domain	Serine/threonine-protein kinase LATS1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase LATS1 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000131037(EPS8L1)	--	3.1291076	128	2.204476056	91	2.865666268	120	1.958092144	79	2.091517283	83	1.811417437	71	0.371594101	-0.715999458	normal	0.966009383	-0.15154361	normal	0.334572202	-0.752958195	normal	0.162211706	-0.562168344	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17277|0|pps:100996162|EPS8L1; EPS8-like 1; K17277 epidermal growth factor receptor kinase substrate 8 (A)	--	[T]	Signal transduction mechanisms	Phosphotyrosine-binding domain;; SH3 domain;; Variant SH3 domain;; Bacterial SH3 domain	Epidermal growth factor receptor kinase substrate 8-like protein 1 GN=EPS8L1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 1 [Ceratotherium simum simum]
ENSG00000131042(LILRB2)	--	0	0	0	0	0.03274348	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06512|0|hsa:10288|LILRB2, CD85D, ILT-4, ILT4, LIR-2, LIR2, MIR-10, MIR10; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2; K06512 leukocyte immunoglobulin-like receptor (A)"	Osteoclast differentiation (ko04380)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Leukocyte immunoglobulin-like receptor subfamily B member 2 (Precursor) GN=LILRB2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X1 [Equus przewalskii]
ENSG00000131043(AAR2)	--	16.43744	774	15.673624	742	14.478208	681	17.888072	846	21.54435069	1012	17.439387	821	0.972999128	0.097307046	normal	0.650033639	0.425546306	normal	0.926204914	0.260907578	normal	0.162301981	0.264810102	normal	--	--	--	"K13205|0|hsa:25980|AAR2, C20orf4; AAR2 splicing factor homolog (S. cerevisiae); K13205 A1 cistron-splicing factor AAR2 (A)"	--	[A]	RNA processing and modification	AAR2 protein	Protein AAR2 homolog GN=AAR2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: protein AAR2 homolog isoform X2 [Canis lupus familiaris] 
ENSG00000131044(TTLL9)	--	0.0438567	3	0	0	0	0	0	0	0.0423678	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16603|0|hsa:164395|TTLL9, C20orf125, dJ310O13.1; tubulin tyrosine ligase-like family, member 9; K16603 tubulin polyglutamylase TTLL9 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Probable tubulin polyglutamylase TTLL9 GN=TTLL9 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: probable tubulin polyglutamylase TTLL9 [Canis lupus familiaris]
ENSG00000131051(RBM39)	--	61.31122614	2886	75.9973392	3552	76.77210399	3378	72.17792957	3285	75.12620412	3333	84.31540334	3734	0.984360962	0.155911972	normal	0.988323234	-0.113187062	normal	0.98745154	0.136203139	normal	0.829074707	0.055934123	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13091|0|tup:102475988|RBM39; RNA binding motif protein 39; K13091 RNA-binding protein 39 (A)	--	[K]	Transcription	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; linker between RRM2 and RRM3 domains in RBM39 protein;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 39 GN=RBM39 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: RNA-binding protein 39 isoform X1 [Erinaceus europaeus]
ENSG00000131061(ZNF341)	--	2.415956326	179	2.636035515	199	1.98691492	150	1.8225208	131	1.657515711	124	2.12827838	161	0.754797672	-0.476423237	normal	0.183963761	-0.697078708	normal	0.964823617	0.09290252	normal	0.299426509	-0.364977349	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 341 GN=ZNF341 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 341 isoformX3 [Canis lupus familiaris]
ENSG00000131067(GGT7)	--	12.716636	538	8.442796805	380	11.81187304	517	5.507357747	245	6.315364381	274	8.327553042	347	1.50E-07	-1.160611664	down	0.526873381	-0.490938145	normal	0.163853204	-0.581430016	normal	0.005521842	-0.748468661	normal	[E]	Amino acid transport and metabolism	Biological Process: glutathione catabolic process (GO:0006751);; Molecular Function: glutathione hydrolase activity (GO:0036374);; 	"K00681|0|hsa:2686|GGT7, D20S101, GGT4, GGTL3, GGTL5, dJ18C9.2; gamma-glutamyltransferase 7 (EC:2.3.2.2 3.4.19.13); K00681 gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] (A)"	Taurine and hypotaurine metabolism (ko00430);; Cyanoamino acid metabolism (ko00460);; Glutathione metabolism (ko00480)	[E]	Amino acid transport and metabolism	Gamma-glutamyltranspeptidase	Gamma-glutamyltransferase 7 light chain (Precursor) GN=GGT7 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: gamma-glutamyltransferase 7 isoform X1 [Tupaia chinensis] 
ENSG00000131069(ACSS2)	--	18.03816249	1063	12.20860998	740	18.62309196	1036	5.890393645	340	6.457027788	380	11.12437278	637	0	-1.670854467	down	1.13E-05	-0.980103315	normal	0.006318778	-0.708617714	normal	0.001853735	-1.083935039	down	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01895|0|hsa:55902|ACSS2, ACAS2, ACECS, ACS, ACSA, dJ1161H23.1; acyl-CoA synthetase short-chain family member 2 (EC:6.2.1.1); K01895 acetyl-CoA synthetase [EC:6.2.1.1] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	"Acetyl-coenzyme A synthetase, cytoplasmic GN=ACSS2 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: acetyl-coenzyme A synthetase, cytoplasmic isoform X1 [Tupaia chinensis]"
ENSG00000131080(EDA2R)	--	11.13193	845	16.37815457	1204	13.396248	1007	9.701820534	758	9.478730051	730	14.50432359	1142	0.957999792	-0.187226082	normal	0.002936637	-0.742083322	normal	0.966408683	0.172963464	normal	0.601492541	-0.236658039	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05163|0|mcf:102116506|EDA2R; ectodysplasin A2 receptor; K05163 tumor necrosis factor receptor superfamily member 27 (A)	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 27 GN=UNQ2448/PRO5727/PRO34080 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 27-like isoform X1 [Lipotes vexillifer]
ENSG00000131089(ARHGEF9)	--	6.865928573	561	6.00186821	533	5.695527236	505	4.844920231	476	4.895788946	430	5.187937244	469	0.917081903	-0.267076268	normal	0.860848307	-0.330180172	normal	0.965234527	-0.114630607	normal	0.299781802	-0.239145697	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; PH domain	Rho guanine nucleotide exchange factor 9 GN=ARHGEF9 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 9 isoform X1 [Camelus dromedarius]
ENSG00000131094(C1QL1)	--	36.79807224	634	35.28875676	613	28.94651477	506	22.26037493	370	25.55476035	423	31.737171	543	0.001326168	-0.805202313	normal	0.218945572	-0.554997572	normal	0.968284471	0.093254278	normal	0.103529658	-0.41229374	normal	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	C1q-related factor (Precursor) GN=C1QL1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: C1q-related factor [Orycteropus afer afer]
ENSG00000131095(GFAP)	--	2.3308075	131	2.61748236	137	4.992653	181	3.812942	152	2.9335887	134	2.2213647	113	0.956904651	0.181692687	normal	0.966298441	-0.052780326	normal	0.258523633	-0.68069352	normal	0.670382696	-0.191848225	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	K05640|0|pps:100978176|GFAP; glial fibrillary acidic protein; K05640 glial fibrillary acidic protein (A)	--	--	--	Intermediate filament protein;; Intermediate filament head (DNA binding) region	Glial fibrillary acidic protein GN=GFAP OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: glial fibrillary acidic protein isoform X1 [Pteropus alecto] 
ENSG00000131096(PYY)	--	0.0736578	1	0	0	0	0	0.392992	2	0.142327	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05233|1.40711e-47|pps:100992835|PYY; peptide YY; K05233 peptide YY (A)	--	--	--	Pancreatic hormone peptide	Peptide YY(3-36) {ECO:0000303|PubMed:2587421} (Precursor) GN=PYY OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	peptide YY precursor [Sus scrofa] 
ENSG00000131097(HIGD1B)	--	0.621494	2	0	0	0.289216	0	0.283033	1	0.30483	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Hypoxia induced protein conserved region	HIG1 domain family member 1B GN=HIGD1B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: HIG1 domain family member 1B [Pteropus alecto]
ENSG00000131100(ATP6V1E1)	--	55.45562237	1522	64.62716503	1767	61.31286982	1663	46.422478	1280	45.44002006	1231	61.60009326	1684	0.928856635	-0.280347733	normal	0.198745312	-0.542338464	normal	0.985160987	0.009803668	normal	0.248831319	-0.259742934	normal	[C]	Energy production and conversion	"Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting two-sector ATPase complex, catalytic domain (GO:0033178);; Molecular Function: proton-transporting ATPase activity, rotational mechanism (GO:0046961);; "	"K02150|1.48147e-112|pps:100988766|ATP6V1E1; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1; K02150 V-type H+-transporting ATPase subunit E (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase (E/31 kDa) subunit	V-type proton ATPase subunit E 1 GN=ATP6V1E1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit E 1 isoform X1 [Canis lupus familiaris]
ENSG00000131115(ZNF227)	--	8.632593167	248	5.650629108	283	8.467425258	297	4.9575885	260	4.990803485	249	7.587833553	282	0.966627049	0.037114671	normal	0.943879367	-0.204914532	normal	0.964728306	-0.08262738	normal	0.824054838	-0.086746592	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7770|ZNF227; zinc finger protein 227; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger of C2H2 type"	Zinc finger protein 227 GN=ZNF227 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 227 [Galeopterus variegatus]
ENSG00000131116(ZNF428)	--	27.62842	622	26.81097708	668	32.21293	714	26.07951	615	25.557611	586	27.69228	659	0.973035645	-0.047043567	normal	0.946994615	-0.209866291	normal	0.96807806	-0.12366433	normal	0.607456448	-0.128418151	normal	--	--	--	--	--	--	--	--	Zinc finger protein 428 GN=ZNF428 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 428 [Condylura cristata]
ENSG00000131127(ZNF141)	--	1.065271802	132	1.181344872	137	2.0120036	176	2.08683872	213	2.464989964	263	2.232305149	244	0.253856553	0.653444589	normal	0.003360856	0.912072426	normal	0.715383868	0.45964575	normal	0.012018776	0.673966841	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7700|ZNF141, D4S90, PAPA6, pHZ-44; zinc finger protein 141; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; XPA protein N-terminal;; Putative zinc ribbon domain;; C1-like domain"	Zinc finger protein 141 GN=ZNF141 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000131143(COX4I1)	--	413.020908	3567	374.7658763	3385	389.3302797	3497	489.821041	4360	471.3445916	4071	444.5428055	3871	0.969179654	0.25868374	normal	0.972240084	0.244701026	normal	0.987638013	0.138240227	normal	0.236909688	0.213995374	normal	--	--	Molecular Function: cytochrome-c oxidase activity (GO:0004129);; 	"K02263|2.81429e-122|ptr:454391|COX4I1; cytochrome c oxidase subunit 4 isoform 1, mitochondrial (EC:1.9.3.1); K02263 cytochrome c oxidase subunit 4 (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome c oxidase subunit IV	"Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (Precursor) GN=COX4I1 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: cytochrome c oxidase subunit 4 isoform 1, mitochondrial-like isoform 2 [Dasypus novemcinctus]"
ENSG00000131148(EMC8)	--	25.61285	804	24.60886	785	25.86582	825	28.46251	908	29.52052	933	26.27552	835	0.96795633	0.14440476	normal	0.945849479	0.227355706	normal	0.977426135	0.009074103	normal	0.581785096	0.1273249	normal	--	--	--	--	--	[R]	General function prediction only	Uncharacterised protein family (UPF0172)	ER membrane protein complex subunit 8 GN=EMC8 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ER membrane protein complex subunit 8 isoform X2 [Galeopterus variegatus]
ENSG00000131149(GSE1)	--	28.17443294	3357	26.75319112	3222	25.29914426	3048	22.72791801	2584	20.9483864	2363	24.13711635	2883	0.771428354	-0.408185089	normal	0.555221041	-0.468505523	normal	0.988450665	-0.088538333	normal	0.046663948	-0.319105036	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3736)	Genetic suppressor element 1 GN=GSE1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: genetic suppressor element 1 isoform X1 [Pteropus alecto]
ENSG00000131153(GINS2)	--	13.4488	677	13.3408	679	16.774692	834	14.3645	730	12.4411	623	10.0981	511	0.972814906	0.07773845	normal	0.96350925	-0.145268062	normal	0.007332335	-0.713346156	normal	0.323841663	-0.254407039	normal	[S]	Function unknown	--	K10733|1.68289e-134|pon:100440406|GINS2; GINS complex subunit 2 (Psf2 homolog); K10733 GINS complex subunit 2 (A)	--	[S]	Function unknown	GINS complex protein	DNA replication complex GINS protein PSF2 GN=GINS2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA replication complex GINS protein PSF2 [Erinaceus europaeus]
ENSG00000131165(CHMP1A)	--	48.294081	2122	41.5178455	1856	46.9655841	2111	50.6326379	2215	50.7273814	2199	45.89534306	2029	0.987367011	0.03102779	normal	0.965875002	0.2230572	normal	0.98607865	-0.065401362	normal	0.810566276	0.060230994	normal	[N]	Cell motility	Biological Process: vacuolar transport (GO:0007034);; 	K12197|2.14011e-120|ptr:739819|CHMP1A; charged multivesicular body protein 1A; K12197 charged multivesicular body protein 1 (A)	Endocytosis (ko04144)	--	--	Snf7	Charged multivesicular body protein 1a OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 1a [Orcinus orca]
ENSG00000131171(SH3BGRL)	--	57.818	1512	66.3577	1720	55.602	1429	63.3242	1676	66.5301	1739	60.9628	1605	0.980014353	0.117618197	normal	0.98511741	-0.005572318	normal	0.974448366	0.159116969	normal	0.713453307	0.085519452	normal	--	--	--	--	--	[S]	Function unknown	"SH3-binding, glutamic acid-rich protein"	SH3 domain-binding glutamic acid-rich-like protein GN=SH3BGRL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SH3 domain-binding glutamic acid-rich-like protein-like isoform X1 [Equus caballus] 
ENSG00000131174(COX7B)	--	35.568421	1158	39.06523826	1263	39.81924555	1273	39.27469	1293	34.99552868	1137	38.91953921	1270	0.975414256	0.128093872	normal	0.96796729	-0.172830709	normal	0.98227358	-0.011681471	normal	0.955665903	-0.018885521	normal	--	--	--	"K02271|6.64191e-54|hsa:1349|COX7B, APLCC; cytochrome c oxidase subunit VIIb (EC:1.9.3.1); K02271 cytochrome c oxidase subunit 7b (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	Cytochrome C oxidase chain VIIB	"Cytochrome c oxidase subunit 7B, mitochondrial (Precursor) GN=COX7B OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: cytochrome c oxidase subunit 7B, mitochondrial-like [Pteropus alecto] "
ENSG00000131183(SLC34A1)	--	0	0	0	0	0.060692475	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: sodium-dependent phosphate transmembrane transporter activity (GO:0015321);; Cellular Component: membrane (GO:0016020);; Biological Process: sodium-dependent phosphate transport (GO:0044341);; 	"K14683|0|pps:100994547|SLC34A1; solute carrier family 34 (type II sodium/phosphate cotransporter), member 1; K14683 solute carrier family 34 (sodium-dependent phosphate cotransporter) (A)"	--	--	--	Na+/Pi-cotransporter	Sodium-dependent phosphate transport protein 2A GN=SLC34A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transport protein 2A [Felis catus]
ENSG00000131187(F12)	--	6.88889	260	5.27951	192	6.30543	243	6.1146	228	6.24368	235	4.55412	172	0.941629753	-0.218927246	normal	0.9247744	0.268215624	normal	0.611613601	-0.5030988	normal	0.688756215	-0.151974288	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	"K01328|0|hsa:2161|F12, HAE3, HAEX, HAF; coagulation factor XII (Hageman factor) (EC:3.4.21.38); K01328 coagulation factor XII (Hageman factor) [EC:3.4.21.38] (A)"	Complement and coagulation cascades (ko04610)	[T]	Signal transduction mechanisms	Trypsin;; Kringle domain;; Fibronectin type II domain;; EGF-like domain;; Fibronectin type I domain;; Human growth factor-like EGF	Coagulation factor XIIa light chain (Precursor) GN=F12 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: coagulation factor XII [Galeopterus variegatus]
ENSG00000131188(PRR7)	--	28.020961	523	24.37207	470	23.565113	466	20.910113	393	26.008196	501	18.31876	347	0.618376762	-0.441611484	normal	0.968478493	0.070503549	normal	0.664181279	-0.432054803	normal	0.276762493	-0.254932871	normal	--	--	--	--	--	--	--	WW domain-binding protein 1	Proline-rich protein 7 GN=PRR7 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: proline-rich protein 7 isoform X2 [Ochotona princeps]
ENSG00000131196(NFATC1)	--	4.312580653	295	3.799356794	230	4.150471178	252	2.662143799	165	2.805603552	192	2.222424604	147	0.004179997	-0.86298153	normal	0.919704053	-0.279936443	normal	0.031884423	-0.779697866	normal	0.011984899	-0.645916056	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K04446|0|hsa:4772|NFATC1, NF-ATC, NFAT2, NFATc; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1; K04446 nuclear factor of activated T-cells, cytoplasmic 1 (A)"	MAPK signaling pathway (ko04010);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Wnt signaling pathway (ko04310);; Osteoclast differentiation (ko04380);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Oxytocin signaling pathway (ko04921);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Inflammatory bowel disease (IBD) (ko05321)	--	--	Rel homology domain (RHD);; IPT/TIG domain	"Nuclear factor of activated T-cells, cytoplasmic 1 GN=NFATC1 OS=Homo sapiens (Human) PE=1 SV=3"	K	Transcription	"PREDICTED: nuclear factor of activated T-cells, cytoplasmic 1 [Oryctolagus cuniculus]"
ENSG00000131203(IDO1)	--	0	0	0	0	0	0	0.119593888	3	0.033111834	0	0.150674143	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: heme binding (GO:0020037);; 	"K00463|0|hsa:3620|IDO1, IDO, IDO-1, INDO; indoleamine 2,3-dioxygenase 1 (EC:1.13.11.52); K00463 indoleamine 2,3-dioxygenase [EC:1.13.11.52] (A)"	Tryptophan metabolism (ko00380);; African trypanosomiasis (ko05143)	--	--	"Indoleamine 2,3-dioxygenase"	"Indoleamine 2,3-dioxygenase 1 GN=IDO1 OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: indoleamine 2,3-dioxygenase 1 [Galeopterus variegatus]"
ENSG00000131233(GJA9)	--	9.826487311	346	9.611162069	300	9.723266309	300	14.01503409	469	11.36619673	406	8.595202002	307	0.73063607	0.406428384	normal	0.734485565	0.413293693	normal	0.967676899	0.024860826	normal	0.313054919	0.298799344	normal	--	--	--	"K07618|0|hsa:81025|GJA9, CX58, CX59, GJA10; gap junction protein, alpha 9, 59kDa; K07618 gap junction alpha-9 protein (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction alpha-9 protein GN=GJA9 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: gap junction alpha-9 protein [Tupaia chinensis]
ENSG00000131236(CAP1)	--	115.1344065	5186	117.3226558	5074	124.9238791	5411	123.6466932	5502	122.9332699	5219	108.1654892	4718	0.993378187	0.054485998	normal	0.993303614	0.019217677	normal	0.984318765	-0.205949571	normal	0.878898821	-0.043056743	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	K17261|0|ggo:101153402|CAP1; adenylyl cyclase-associated protein 1 isoform 1; K17261 adenylyl cyclase-associated protein (A)	--	[ZT]	Cytoskeleton;; Signal transduction mechanisms	Adenylate cyclase associated (CAP) N terminal;; Adenylate cyclase associated (CAP) C terminal	Adenylyl cyclase-associated protein 1 GN=CAP1 OS=Homo sapiens (Human) PE=1 SV=5	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: adenylyl cyclase-associated protein 1 [Tupaia chinensis] 
ENSG00000131238(PPT1)	--	36.27549269	1554	37.549418	1666	39.46593408	1671	27.10068697	1150	29.37358238	1240	31.415659	1319	0.485209741	-0.464648582	normal	0.586722822	-0.447002644	normal	0.854503381	-0.34920203	normal	0.00582654	-0.419811397	normal	[R]	General function prediction only	Molecular Function: palmitoyl hydrolase activity (GO:0098599);; 	"K01074|0|hsa:5538|PPT1, CLN1, INCL, PPT; palmitoyl-protein thioesterase 1 (EC:3.1.2.22); K01074 palmitoyl-protein thioesterase [EC:3.1.2.22] (A)"	Fatty acid elongation (ko00062);; Fatty acid metabolism (ko01212);; Lysosome (ko04142)	[IO]	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Palmitoyl protein thioesterase	Palmitoyl-protein thioesterase 1 (Precursor) GN=PPT1 OS=Homo sapiens (Human) PE=1 SV=1	IO	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: palmitoyl-protein thioesterase 1 [Ursus maritimus]
ENSG00000131242(RAB11FIP4)	--	2.287256559	226	1.75395019	171	1.366601948	161	1.499705695	134	1.943793	164	1.611964702	155	0.044488654	-0.777970076	normal	0.963847526	-0.080995556	normal	0.966327879	-0.062485684	normal	0.360462383	-0.321748225	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K12485|0|hsa:84440|RAB11FIP4, RAB11-FIP4; RAB11 family interacting protein 4 (class II); K12485 Rab11 family-interacting protein 3/4 (A)"	Endocytosis (ko04144)	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	FIP domain	Rab11 family-interacting protein 4 GN=RAB11FIP4 OS=Homo sapiens (Human) PE=1 SV=1	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: rab11 family-interacting protein 4 isoform X1 [Felis catus]
ENSG00000131263(RLIM)	--	13.84476465	1905	14.18799637	1943	14.93895865	2013	15.29420572	2121	16.48300813	2266	15.47707467	2133	0.982329529	0.124026533	normal	0.972157207	0.200290936	normal	0.985708712	0.07519047	normal	0.520753853	0.132666706	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K16271|0|hsa:51132|RLIM, NY-REN-43, RNF12; ring finger protein, LIM domain interacting; K16271 E3 ubiquitin-protein ligase RLIM [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Anaphase-promoting complex subunit 11 RING-H2 finger"	E3 ubiquitin-protein ligase RLIM GN=RLIM OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RLIM isoform X1 [Leptonychotes weddellii] 
ENSG00000131269(ABCB7)	--	13.40089147	543	15.6473338	650	10.53292528	511	11.17633333	563	15.20770438	564	13.48830625	635	0.972573873	0.021291297	normal	0.94059198	-0.225607058	normal	0.887954706	0.304332411	normal	0.942006284	0.027139999	normal	--	--	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05662|0|pps:100981467|ABCB7; ATP-binding cassette, sub-family B (MDR/TAP), member 7; K05662 ATP-binding cassette, subfamily B (MDR/TAP), member 7 (A)"	ABC transporters (ko02010)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ABC transporter;; ABC transporter transmembrane region	"ATP-binding cassette sub-family B member 7, mitochondrial (Precursor) GN=ABCB7 OS=Homo sapiens (Human) PE=1 SV=2"	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: ATP-binding cassette sub-family B member 7, mitochondrial isoform X1 [Oryctolagus cuniculus]"
ENSG00000131323(TRAF3)	--	14.19104293	1987	13.72522944	1985	15.32628971	2025	13.64088208	1870	14.10935005	2033	12.3653521	1764	0.982317413	-0.118291556	normal	0.986530487	0.013034837	normal	0.968764117	-0.207196858	normal	0.640130864	-0.102919767	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	K03174|0|ptr:453178|TRAF3; TNF receptor-associated factor 3; K03174 TNF receptor-associated factor 3 (A)	NF-kappa B signaling pathway (ko04064);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; TNF signaling pathway (ko04668);; Hepatitis C (ko05160);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	MATH domain;; TRAF-type zinc finger	TNF receptor-associated factor 3 GN=TRAF3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TNF receptor-associated factor 3 isoform X5 [Tupaia chinensis] 
ENSG00000131351(HAUS8)	--	5.810198	199	5.712460269	201	5.657540005	199	7.4076669	262	6.1063996	209	3.6270121	127	0.854720946	0.363513703	normal	0.965364935	0.034625403	normal	0.286542694	-0.649995727	normal	0.978713058	-0.025640761	normal	--	--	--	K16591|0|ggo:101140500|HAUS8; HAUS augmin-like complex subunit 8; K16591 HAUS augmin-like complex subunit 8 (A)	--	--	--	--	HAUS augmin-like complex subunit 8 GN=HAUS8 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: HAUS augmin-like complex subunit 8 isoform X1 [Galeopterus variegatus]
ENSG00000131368(MRPS25)	--	15.503813	1005	17.31752	1108	19.87004	1089	18.94217	1173	17.01483	1096	16.32795	1030	0.962081717	0.191903496	normal	0.979736462	-0.037085747	normal	0.977269869	-0.088524634	normal	0.947441852	0.021505257	normal	--	--	--	K17404|5.7324e-117|ptr:100614995|MRPS25; mitochondrial ribosomal protein S25; K17404 small subunit ribosomal protein S25 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain	"28S ribosomal protein S25, mitochondrial GN=MRPS25 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S25, mitochondrial [Trichechus manatus latirostris]"
ENSG00000131370(SH3BP5)	--	6.274995499	377	5.353958742	336	6.269987515	352	6.474381158	399	5.886720122	353	5.452659356	333	0.968291312	0.050790748	normal	0.966634918	0.049562751	normal	0.965123555	-0.087956121	normal	0.994752228	0.005082996	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	SH3 domain-binding protein 5 (SH3BP5)	SH3 domain-binding protein 5 GN=SH3BP5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SH3 domain-binding protein 5 [Orycteropus afer afer]
ENSG00000131373(HACL1)	--	13.61883155	489	11.36745716	401	12.82079795	454	12.505407	441	14.74283605	517	13.25300541	460	0.952984621	-0.179294499	normal	0.843919497	0.343990289	normal	0.970920486	0.010614994	normal	0.872387282	0.056409841	normal	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	"Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: catalytic activity (GO:0003824);; Biological Process: methanogenesis, from acetate (GO:0019385);; Molecular Function: thiamine pyrophosphate binding (GO:0030976);; "	K12261|0|pps:100982158|HACL1; 2-hydroxyacyl-CoA lyase 1; K12261 2-hydroxyacyl-CoA lyase 1 [EC:4.1.-.-] (A)	Peroxisome (ko04146)	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	"Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;; Thiamine pyrophosphate enzyme, central domain;; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;; CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit"	2-hydroxyacyl-CoA lyase 1 GN=HACL1 OS=Homo sapiens (Human) PE=1 SV=2	EH	Amino acid transport and metabolism;; Coenzyme transport and metabolism	PREDICTED: 2-hydroxyacyl-CoA lyase 1 isoform X1 [Galeopterus variegatus]
ENSG00000131374(TBC1D5)	--	23.96461734	2335	20.01312826	2189	30.6119222	2209	18.5607847	1809	18.026005	1892	23.3170283	2125	0.765489456	-0.398763361	normal	0.963484909	-0.231614129	normal	0.986559125	-0.06417722	normal	0.187641475	-0.229479049	normal	[R]	General function prediction only	--	"K18469|0|hsa:9779|TBC1D5; TBC1 domain family, member 5; K18469 TBC1 domain family member 5 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	TBC1 domain family member 5 GN=TBC1D5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 5 isoform X2 [Mustela putorius furo] 
ENSG00000131375(CAPN7)	--	11.37853005	857	12.81753036	959	10.913347	804	10.558073	798	9.577968993	718	12.066198	893	0.969143755	-0.133490628	normal	0.605440962	-0.438171917	normal	0.968201353	0.142918054	normal	0.530077875	-0.142272159	normal	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K08576|0|hsa:23473|CAPN7, CALPAIN7, PALBH; calpain 7; K08576 calpain-7 [EC:3.4.22.-] (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; MIT (microtubule interacting and transport) domain;; Calpain large subunit, domain III"	Calpain-7 GN=CAPN7 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-7 [Odobenus rosmarus divergens]
ENSG00000131378(RFTN1)	--	2.338213	147	2.945758254	190	2.303898877	150	5.25854541	335	8.62768836	442	8.7227775	557	5.22E-06	1.149343189	up	3.81E-07	1.190231675	up	0	1.873915377	up	0.000155181	1.433841093	up	--	--	--	--	--	--	--	Raftlin	Raftlin GN=RFTN1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: raftlin [Galeopterus variegatus]
ENSG00000131379(C3orf20)	--	4.260514785	388	4.186530758	373	3.734268991	331	4.52672478	431	4.634555274	418	5.027908907	421	0.962798818	0.120346673	normal	0.958521113	0.142355335	normal	0.856712429	0.337327895	normal	0.46713442	0.196354787	normal	--	--	--	--	--	--	--	FAM194 protein	Uncharacterized protein C3orf20 GN=C3orf20 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C3orf20 homolog [Galeopterus variegatus]
ENSG00000131381(RBSN)	--	6.283718911	797	6.032450594	807	6.000034301	770	6.11711247	856	6.620159302	889	7.6111628	1003	0.975174077	0.072064747	normal	0.971023975	0.117977492	normal	0.788375303	0.372457098	normal	0.357659501	0.190270752	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K12481|0|hsa:64145|RBSN, Rabenosyn-5, ZFYVE20; rabenosyn, RAB effector; K12481 rabenosyn-5 (A)"	Endocytosis (ko04144)	[R]	General function prediction only	Rabenosyn Rab binding domain;; FYVE zinc finger	Rabenosyn-5 GN=ZFYVE20 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rabenosyn-5 isoform 1 [Ceratotherium simum simum] 
ENSG00000131386(GALNT15)	--	0	0	0	0	0	0	0	0	0.037275707	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K00710|0|hsa:117248|GALNT15, GALNACT15, GALNT13, GALNT7, GALNTL2, PIH5; polypeptide N-acetylgalactosaminyltransferase 15 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 15 GN=GALNT15 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase-like protein 2 [Ceratotherium simum simum]
ENSG00000131389(SLC6A6)	--	50.57481	6280	51.35612	6492	44.231906	5357	33.63393	4059	30.930219	3715	39.612623	4839	0.017725885	-0.660269799	normal	0.000172094	-0.826469357	normal	0.989324272	-0.154961749	normal	0.001043547	-0.544404618	normal	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05039|0|hsa:6533|SLC6A6, TAUT; solute carrier family 6 (neurotransmitter transporter), member 6; K05039 solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium- and chloride-dependent taurine transporter GN=SLC6A6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium- and chloride-dependent taurine transporter isoform X1 [Oryctolagus cuniculus]
ENSG00000131398(KCNC3)	--	1.688734003	116	2.73054	161	1.572273346	95	0.493025905	47	0.777270018	52	1.100373	85	0.000705512	-1.306110028	down	2.00E-07	-1.623630785	down	0.965814627	-0.165961586	normal	0.027017591	-1.035706831	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04889|0|hsa:3748|KCNC3, KSHIIID, KV3.3, SCA13; potassium voltage-gated channel, Shaw-related subfamily, member 3; K04889 potassium voltage-gated channel Shaw-related subfamily C member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel;; Potassium voltage-gated channel	Potassium voltage-gated channel subfamily C member 3 GN=KCNC3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily C member 3 [Orcinus orca]
ENSG00000131400(NAPSA)	--	1.002613	36	0.438598	16	0.732478116	23	0.433012	16	0.7240742	25	0.898208641	32	0.692439453	-1.126785282	normal	0.973782047	0.578403367	normal	0.974432791	0.443336445	normal	0.97296766	-0.058197403	normal	--	--	--	"K08565|0|hsa:9476|NAPSA, KAP, Kdap, NAP1, NAPA, SNAPA; napsin A aspartic peptidase; K08565 napsin-A [EC:3.4.23.-] (A)"	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Eukaryotic aspartyl protease	Napsin-A (Precursor) GN=NAPSA OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: napsin-A [Galeopterus variegatus]
ENSG00000131408(NR1H2)	--	56.8710815	2057	60.61591127	2210	57.76094227	2173	45.0201695	1639	49.03067823	1760	58.38625605	2121	0.850031886	-0.35825766	normal	0.874091205	-0.349628754	normal	0.987058892	-0.04320456	normal	0.157830849	-0.242791267	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08535|0|ptr:456227|NR1H2; nuclear receptor subfamily 1, group H, member 2; K08535 liver X receptor beta (A)"	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Oxysterols receptor LXR-beta GN=NR1H2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: oxysterols receptor LXR-beta isoform X1 [Mustela putorius furo] 
ENSG00000131409(LRRC4B)	--	2.603632016	156	1.479237193	87	1.155132659	71	0.559119956	32	1.715459568	99	0.567744916	33	1.48E-12	-2.261858586	down	0.964116428	0.162339894	normal	0.1558714	-1.079138692	normal	0.322127043	-0.95831705	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K16360|0|ptr:468964|LRRC4B; leucine rich repeat containing 4B; K16360 netrin-G3 ligand (A)	Cell adhesion molecules (CAMs) (ko04514)	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Leucine rich repeat;; Immunoglobulin domain;; Leucine rich repeat N-terminal domain	Leucine-rich repeat-containing protein 4B (Precursor) GN=LRRC4B OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	leucine-rich repeat-containing protein 4B precursor [Bos taurus] 
ENSG00000131435(PDLIM4)	--	0	0	0.190624	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	PDZ domain (Also known as DHR or GLGF);; LIM domain	PDZ and LIM domain protein 4 GN=PDLIM4 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: PDZ and LIM domain protein 4 [Camelus bactrianus] 
ENSG00000131437(KIF3A)	--	7.794134569	688	6.842388206	673	8.01518749	755	6.662235946	624	6.315158712	589	6.054175959	576	0.958920957	-0.171292907	normal	0.945896746	-0.213252747	normal	0.725412233	-0.397784171	normal	0.193939593	-0.263432455	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10394|0|hsa:11127|KIF3A, FLA10, KLP-20; kinesin family member 3A; K10394 kinesin family member 3/17 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF3A GN=KIF3A OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF3A isoform X1 [Bison bison bison]
ENSG00000131446(MGAT1)	--	37.5064955	1806	34.18426674	1770	36.3747765	1769	32.1835957	1559	34.8073844	1660	35.02305215	1679	0.954629048	-0.242786663	normal	0.980936785	-0.113892171	normal	0.983387905	-0.083549935	normal	0.466182015	-0.146959528	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; 	"K00726|0|hsa:4245|MGAT1, GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, MGAT; mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.101); K00726 alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.101] (A)"	N-Glycan biosynthesis (ko00510)	[G]	Carbohydrate transport and metabolism	GNT-I family	"Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase GN=MGAT1 OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X2 [Galeopterus variegatus]"
ENSG00000131459(GFPT2)	--	24.94382615	1564	13.55088108	849	24.05704	1491	25.782966	1619	21.68987636	1354	16.35180868	1019	0.984547673	0.019011853	normal	0.02457239	0.651038649	normal	0.139548448	-0.556730353	normal	0.990393591	0.010115458	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: carbohydrate derivative binding (GO:0097367);; Biological Process: carbohydrate derivative metabolic process (GO:1901135);; 	K00820|0|pps:100990871|GFPT2; glutamine-fructose-6-phosphate transaminase 2; K00820 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] (A)	"Alanine, aspartate and glutamate metabolism (ko00250);; Amino sugar and nucleotide sugar metabolism (ko00520)"	[M]	Cell wall/membrane/envelope biogenesis	SIS domain;; Glutamine amidotransferases class-II;; Glutamine amidotransferase domain;; Glutamine amidotransferase domain;; Glutamine amidotransferases class-II	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 GN=GFPT2 OS=Homo sapiens (Human) PE=1 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: glutamine--fructose-6-phosphate aminotransferase [isomerizing] 2 isoform X2 [Lipotes vexillifer]
ENSG00000131462(TUBG1)	--	70.9121253	2160	57.6065	1778	76.4602	2379	60.191361	1844	52.0102286	1577	52.489314	1608	0.952130858	-0.258825401	normal	0.969399705	-0.194323593	normal	0.103915556	-0.572933398	normal	0.068908038	-0.350240483	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K10389|0|pps:100992055|TUBG1; tubulin, gamma 1; K10389 tubulin gamma (A)"	--	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin gamma-1 chain GN=TUBG1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tubulin gamma-1 chain [Galeopterus variegatus]
ENSG00000131467(PSME3)	--	84.33482783	4063	81.49144207	4120	88.1616	4094	115.2237221	5414	109.6227677	5395	87.962617	4418	0.872066187	0.383191364	normal	0.902148681	0.367433888	normal	0.99074793	0.101554755	normal	0.087366806	0.288934541	normal	--	--	Cellular Component: proteasome activator complex (GO:0008537);; 	"K06698|0|myb:102258135|PSME3; proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki); K06698 proteasome activator subunit 3 (PA28 gamma) (A)"	Proteasome (ko03050);; Antigen processing and presentation (ko04612);; Hepatitis C (ko05160)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome activator pa28 beta subunit;; Proteasome activator pa28 alpha subunit	Proteasome activator complex subunit 3 GN=PSME3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome activator complex subunit 3 isoform X1 [Myotis brandtii]
ENSG00000131469(RPL27)	--	1536.439221	7169	1545.795411	7375	1495.370953	7253	1858.033347	9471	1771.761877	8275	1525.015041	7403	0.925907717	0.370843269	normal	0.992710712	0.14466169	normal	0.995105548	0.021236355	normal	0.363563573	0.184412663	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02901|8.98206e-65|clv:102095478|RPL27; ribosomal protein L27; K02901 large subunit ribosomal protein L27e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L27e protein family	60S ribosomal protein L27 GN=RPL27 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L27-like [Bubalus bubalis]
ENSG00000131470(PSMC3IP)	--	15.38345795	397	14.83890437	436	18.69201717	501	15.880755	438	13.315617	331	12.93259515	353	0.964159066	0.110552178	normal	0.715839187	-0.417256682	normal	0.383737391	-0.511584521	normal	0.257224202	-0.271329334	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: reciprocal meiotic recombination (GO:0007131);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	"K06695|7.5424e-147|pon:100457033|PSMC3IP; PSMC3 interacting protein; K06695 26S proteasome regulatory subunit, ATPase 3, interacting protein (A)"	--	[T]	Signal transduction mechanisms	Tat binding protein 1(TBP-1)-interacting protein (TBPIP);; Penicillinase repressor	Homologous-pairing protein 2 homolog GN=PSMC3IP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: homologous-pairing protein 2 homolog [Felis catus]
ENSG00000131471(AOC3)	--	0.895377	51	0.947786252	67	0.589787255	40	0.331693557	18	0.316772368	18	0.37230843	27	0.051991209	-1.456318473	normal	0.000250772	-1.832339686	down	0.95374855	-0.549875161	normal	0.007380523	-1.347192241	down	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: copper ion binding (GO:0005507);; Molecular Function: primary amine oxidase activity (GO:0008131);; Biological Process: amine metabolic process (GO:0009308);; Molecular Function: quinone binding (GO:0048038);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00276|0|pps:100973737|AOC3; amine oxidase, copper containing 3; K00276 primary-amine oxidase [EC:1.4.3.21] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; beta-Alanine metabolism (ko00410)"	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Copper amine oxidase, enzyme domain;; Copper amine oxidase, N2 domain;; Copper amine oxidase, N3 domain"	Membrane primary amine oxidase GN=AOC3 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: membrane primary amine oxidase-like isoform X1 [Myotis brandtii] 
ENSG00000131473(ACLY)	--	181.0749813	16671	166.0524625	15302	204.5919866	18809	206.8050506	19088	193.082973	17838	182.8750449	16762	0.995921688	0.164478865	normal	0.994143661	0.199788781	normal	0.995546825	-0.174505421	normal	0.841859389	0.059013679	normal	[C]	Energy production and conversion	"Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer (GO:0046912);; Molecular Function: cofactor binding (GO:0048037);; "	"K01648|0|hsa:47|ACLY, ACL, ATPCL, CLATP; ATP citrate lyase (EC:2.3.3.8); K01648 ATP citrate (pro-S)-lyase [EC:2.3.3.8] (A)"	Citrate cycle (TCA cycle) (ko00020)	[C]	Energy production and conversion	Citrate synthase;; CoA-ligase;; CoA binding domain;; ATP-grasp domain	ATP-citrate synthase GN=ACLY OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: ATP-citrate synthase isoformX1 [Equus caballus] 
ENSG00000131475(VPS25)	--	52.09074421	993	50.427636	965	47.85904945	917	59.1816414	1142	63.85378035	1188	57.18945526	1102	0.966648225	0.170618459	normal	0.923783691	0.27811402	normal	0.935237451	0.256452832	normal	0.20477528	0.234115259	normal	--	--	--	K12189|1.93147e-117|ptr:100611125|VPS25; vacuolar protein sorting 25 homolog (S. cerevisiae); K12189 ESCRT-II complex subunit VPS25 (A)	Endocytosis (ko04144)	[S]	Function unknown	ESCRT-II complex subunit	Vacuolar protein-sorting-associated protein 25 GN=VPS25 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein-sorting-associated protein 25 [Tupaia chinensis] 
ENSG00000131477(RAMP2)	--	0.461027715	4	0.110297713	1	0	0	0.109669149	1	0.335099619	2	0.224876181	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: regulation of G-protein coupled receptor protein signaling pathway (GO:0008277);; Molecular Function: protein transporter activity (GO:0008565);; Cellular Component: integral component of membrane (GO:0016021);; 	K08448|2.23663e-108|hsa:10266|RAMP2; receptor (G protein-coupled) activity modifying protein 2; K08448 receptor activity modifying protein 2 (A)	Vascular smooth muscle contraction (ko04270)	--	--	Receptor activity modifying family	Receptor activity-modifying protein 2 (Precursor) GN=RAMP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor activity-modifying protein 2 [Canis lupus familiaris]
ENSG00000131480(AOC2)	--	1.895177	89	1.749587	84	1.568861	74	1.5029	69	1.504797	70	1.717828	80	0.929833976	-0.390364506	normal	0.954826948	-0.278951128	normal	0.971771798	0.10217463	normal	0.748078302	-0.194593996	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: copper ion binding (GO:0005507);; Molecular Function: primary amine oxidase activity (GO:0008131);; Biological Process: amine metabolic process (GO:0009308);; Molecular Function: quinone binding (GO:0048038);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00276|0|ptr:100610374|AOC2; amine oxidase, copper containing 2 (retina-specific); K00276 primary-amine oxidase [EC:1.4.3.21] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; beta-Alanine metabolism (ko00410)"	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Copper amine oxidase, enzyme domain;; Copper amine oxidase, N3 domain;; Copper amine oxidase, N2 domain"	Retina-specific copper amine oxidase (Precursor) GN=AOC2 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: retina-specific copper amine oxidase [Galeopterus variegatus]
ENSG00000131495(NDUFA2)	--	56.24008	562	62.2318	630	58.00954	595	75.411	792	70.0604	702	69.2081	701	0.503823472	0.463027158	normal	0.965528044	0.134386942	normal	0.940981187	0.227699595	normal	0.167018647	0.275059417	normal	--	--	--	"K03946|1.4128e-62|pps:100972118|NDUFA2; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa; K03946 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 2 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 GN=NDUFA2 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 [Oryctolagus cuniculus]
ENSG00000131503(ANKHD1)	--	25.41560726	2720	30.74836589	3349	26.94687715	3024	25.59829587	2830	25.72080912	2931	32.12294894	3518	0.989502239	0.026348547	normal	0.97629239	-0.213660742	normal	0.977682753	0.20990849	normal	0.985016047	0.008619079	normal	[R]	General function prediction only	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	K16726|0|ggo:101139552|ANKHD1; ankyrin repeat and KH domain-containing protein 1 isoform 1; K16726 ankyrin repeat domain-containing protein 17 (A)	--	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; KH domain;; KH domain	Ankyrin repeat and KH domain-containing protein 1 GN=ANKHD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	ankyrin repeat and KH domain-containing protein 1 [Equus caballus] 
ENSG00000131504(DIAPH1)	--	26.1081762	3059	25.63214447	3074	26.41208789	3172	36.09703394	4245	32.60562226	3774	28.3574746	3342	0.681004543	0.441683132	normal	0.960398798	0.274428674	normal	0.989933558	0.066996399	normal	0.116946447	0.266155731	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	"K05740|0|hsa:1729|DIAPH1, DFNA1, DIA1, DRF1, LFHL1, hDIA1; diaphanous-related formin 1; K05740 diaphanous 1 (A)"	Focal adhesion (ko04510);; Regulation of actin cytoskeleton (ko04810);; Shigellosis (ko05131)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain;; Formin Homology Region 1;; DRF Autoregulatory Domain	Protein diaphanous homolog 1 GN=DIAPH1 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: protein diaphanous homolog 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000131507(NDFIP1)	--	60.3341479	2243	66.10228	2530	64.576724	2345	67.621328	2623	60.725926	2287	68.364115	2525	0.975769968	0.19483242	normal	0.979810561	-0.167002527	normal	0.986178543	0.098342893	normal	0.878142483	0.041441082	normal	--	--	Biological Process: vacuolar transport (GO:0007034);; Biological Process: metal ion transport (GO:0030001);; 	--	--	[R]	General function prediction only	Protein of unknown function (DUF2370)	NEDD4 family-interacting protein 1 GN=NDFIP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: NEDD4 family-interacting protein 1 [Condylura cristata]
ENSG00000131508(UBE2D2)	--	116.2869515	2703	121.8268919	2855	115.0101952	2620	115.8910085	2756	111.6947703	2684	113.78352	2555	0.989519941	-0.002816302	normal	0.986471522	-0.110472266	normal	0.988654266	-0.044508946	normal	0.833277129	-0.054175829	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K06689|2.08086e-103|xtr:548818|ube2d3, Xubc4, e2(17)kb3, ubc4/5, ubch5c, ube2d3.1; ubiquitin-conjugating enzyme E2D 3; K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 D2 GN=UBE2D2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	ubiquitin-conjugating enzyme E2 D2 [Sus scrofa] 
ENSG00000131558(EXOC4)	--	30.00655	2490	28.16713005	2276	27.654745	2310	26.188264	2126	29.82740001	2449	29.33350109	2359	0.956055818	-0.258663452	normal	0.986267898	0.08421171	normal	0.988135944	0.021976887	normal	0.845186733	-0.050114682	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: protein transport (GO:0015031);; 	"K06111|0|ptr:463740|EXOC4, SEC8L1; exocyst complex component 4; K06111 exocyst complex component 4 (A)"	Tight junction (ko04530)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec8 exocyst complex component specific domain	Exocyst complex component 4 GN=EXOC4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 4 isoform 1 [Ceratotherium simum simum]
ENSG00000131584(ACAP3)	--	6.610537727	473	6.488177	466	5.232438145	416	7.5861512	538	7.348158371	548	7.314567473	502	0.959272761	0.15446306	normal	0.94361484	0.211785036	normal	0.920124507	0.261944354	normal	0.389155108	0.207343289	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	"K12489|0|hsa:116983|ACAP3, CENTB5; ArfGAP with coiled-coil, ankyrin repeat and PH domains 3; K12489 Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; Ankyrin repeat;; PH domain;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 GN=ACAP3 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 3 [Leptonychotes weddellii]"
ENSG00000131591(C1orf159)	--	9.91632842	313	8.115574263	290	9.889599707	338	8.504463898	289	7.932150214	274	8.358406331	297	0.957585331	-0.145183466	normal	0.961814873	-0.102752209	normal	0.947568965	-0.193925444	normal	0.639779573	-0.150766693	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4501)	Uncharacterized protein C1orf159 (Precursor) GN=C1orf159 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C1orf159 homolog isoform X2 [Galeopterus variegatus]
ENSG00000131620(ANO1)	--	0.04321459	3	0.201743552	4	0.149328281	4	0.135465158	9	0.2404358	13	0.028472235	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[S]	Function unknown	Calcium-activated chloride channel	Anoctamin-1 GN=ANO1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: anoctamin-1 isoform X2 [Loxodonta africana]
ENSG00000131626(PPFIA1)	--	12.95888286	1335	13.40946273	1482	12.62100475	1399	16.25961665	1556	15.93396786	1640	18.0171269	1705	0.967744562	0.189967404	normal	0.978765615	0.124602905	normal	0.934715732	0.276812869	normal	0.290718526	0.196264208	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Liprin-alpha-1 GN=PPFIA1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: liprin-alpha-1 isoform X5 [Tupaia chinensis]
ENSG00000131634(TMEM204)	--	0.132337	4	0.0740965	2	0.036137	0	0.228067	7	0.22356848	6	0.150809	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 204 GN=TMEM204 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 204 [Orcinus orca] 
ENSG00000131650(KREMEN2)	--	6.7238497	236	3.502773	123	4.641207	166	1.241894881	45	2.121882	70	0.6462595	23	0	-2.381938768	down	0.183766149	-0.821094941	normal	0	-2.780688108	down	0.000756544	-1.949908487	down	--	--	--	--	--	[GO]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Kringle domain;; WSC domain;; CUB domain	Kremen protein 2 (Precursor) GN=KREMEN2 OS=Homo sapiens (Human) PE=2 SV=1	GO	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: kremen protein 2 [Canis lupus familiaris]
ENSG00000131652(THOC6)	--	15.85311664	384	14.627409	366	15.418	386	12.792955	312	16.875692	404	17.75545842	433	0.868231764	-0.328929351	normal	0.961500142	0.120610622	normal	0.957089113	0.156894083	normal	0.996314771	-0.003700735	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K13175|0|pps:100994407|THOC6; THO complex 6 homolog (Drosophila); K13175 THO complex subunit 6 (A)	RNA transport (ko03013)	[R]	General function prediction only	"WD domain, G-beta repeat"	THO complex subunit 6 homolog GN=THOC6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: THO complex subunit 6 homolog isoform X2 [Ursus maritimus]
ENSG00000131653(TRAF7)	--	29.32390361	2310	25.88549052	2047	28.0079413	2180	27.28690517	2172	26.53790213	2043	30.08457175	2388	0.983942395	-0.119618941	normal	0.986591481	-0.024230538	normal	0.983884908	0.123101642	normal	0.98564369	-0.006418807	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10646|0|hsa:84231|TRAF7, RFWD1, RNF119; TNF receptor-associated factor 7, E3 ubiquitin protein ligase; K10646 E3 ubiquitin-protein ligase TRAF7 [EC:6.3.2.19] (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Zinc finger, C3HC4 type (RING finger);; TRAF-type zinc finger;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRAF7 GN=TRAF7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: E3 ubiquitin-protein ligase TRAF7 [Vicugna pacos]
ENSG00000131668(BARX1)	--	24.051566	493	19.585549	390	20.608501	432	13.457476	279	14.002918	303	11.821961	231	0.00094028	-0.848588502	normal	0.793958285	-0.383889113	normal	0.000403228	-0.907015939	normal	0.000374339	-0.715362696	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09361|2.63386e-136|ptr:745472|BARX1; BARX homeobox 1; K09361 BarH-like homeobox (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein BarH-like 1 GN=BARX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein BarH-like 1 [Lipotes vexillifer]
ENSG00000131669(NINJ1)	--	53.2186	1172	51.9934	1150	53.4824	1200	49.7965	1092	53.3435	1172	58.7255	1305	0.973756745	-0.132651761	normal	0.980812803	0.00590446	normal	0.977415859	0.112587865	normal	0.998954421	-0.001460311	normal	--	--	Biological Process: cell adhesion (GO:0007155);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: tissue regeneration (GO:0042246);; 	--	--	--	--	Ninjurin	Ninjurin-1 GN=NINJ1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ninjurin-1 [Erinaceus europaeus]
ENSG00000131697(NPHP4)	--	2.501317	246	2.787434	269	2.315882	229	2.803523	265	2.438152	245	2.294564	216	0.964777877	0.076044137	normal	0.954771633	-0.155335511	normal	0.963601921	-0.091982173	normal	0.899311644	-0.057352306	normal	--	--	--	K16478|0|pps:100980206|NPHP4; nephronophthisis 4; K16478 nephrocystin-4 (A)	--	--	--	--	Nephrocystin-4 GN=NPHP4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: nephrocystin-4 [Tupaia chinensis]
ENSG00000131711(MAP1B)	--	32.93679	9154	39.08625	10702	38.55137	10500	59.97795	16540	53.05864	14650	49.65905	13763	0.000214452	0.822548672	normal	0.870193558	0.431541359	normal	0.933059325	0.382066002	normal	0.000803591	0.544737142	normal	--	--	--	"K10429|0|hsa:4131|MAP1B, FUTSCH, MAP5, PPP1R102; microtubule-associated protein 1B; K10429 microtubule-associated protein 1 (A)"	--	[Z]	Cytoskeleton	Neuraxin and MAP1B repeat	MAP1 light chain LC1 GN=MAP1B OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: microtubule-associated protein 1B [Galeopterus variegatus]
ENSG00000131721(RHOXF2)	--	0.0209085	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[R]	General function prediction only	Homeobox domain	Rhox homeobox family member 2 GN=RHOXF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: rhox homeobox family member 2-like [Orycteropus afer afer]
ENSG00000131724(IL13RA1)	--	28.781129	2029	28.04622526	1994	28.25962	1905	41.285796	2913	40.29590373	2837	38.37200911	2721	0.41074092	0.490593041	normal	0.454431217	0.486963093	normal	0.335472632	0.50571688	normal	0.00067423	0.493505284	normal	--	--	--	"K05076|0|pps:100967748|IL13RA1; interleukin 13 receptor, alpha 1; K05076 interleukin 13 receptor alpha-1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	"Interleukin-6 receptor alpha chain, binding;; Fibronectin type III domain;; Tissue factor"	Interleukin-13 receptor subunit alpha-1 (Precursor) GN=IL13RA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-13 receptor subunit alpha-1 [Equus przewalskii]
ENSG00000131725(WDR44)	--	6.774141072	505	6.200193195	455	6.875073411	502	8.085943918	605	7.137320335	528	7.135132954	532	0.938049013	0.229181793	normal	0.949370542	0.192649997	normal	0.969605804	0.075227274	normal	0.510659965	0.166058341	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 44 GN=WDR44 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 44 isoformX1 [Equus caballus]
ENSG00000131730(CKMT2)	--	0	0	0	0	0	0	0.035685837	1	0	0	0.204257	1	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	"Molecular Function: kinase activity (GO:0016301);; Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	"K00933|0|ptr:461770|CKMT2; creatine kinase, mitochondrial 2 (sarcomeric); K00933 creatine kinase [EC:2.7.3.2] (A)"	Arginine and proline metabolism (ko00330)	[C]	Energy production and conversion	"ATP:guanido phosphotransferase, C-terminal catalytic domain;; ATP:guanido phosphotransferase, N-terminal domain"	"Creatine kinase S-type, mitochondrial (Precursor) GN=CKMT2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: creatine kinase S-type, mitochondrial [Galeopterus variegatus]"
ENSG00000131732(ZCCHC9)	--	14.30983112	433	12.63714	409	15.39377002	460	13.85374281	420	15.08600748	464	14.7124162	480	0.967688572	-0.074541377	normal	0.956107424	0.160041554	normal	0.969980104	0.052938718	normal	0.898714033	0.046520548	normal	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	"K17578|0|hsa:84240|ZCCHC9, PPP1R41; zinc finger, CCHC domain containing 9; K17578 zinc finger CCHC domain-containing protein 9 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Zinc knuckle	Zinc finger CCHC domain-containing protein 9 GN=ZCCHC9 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: zinc finger CCHC domain-containing protein 9 [Galeopterus variegatus]
ENSG00000131737(KRT34)	--	0.167532438	6	0.227283829	5	0.399444546	8	1.014203	25	0.298265949	10	0.457167	15	0.391896013	1.789220534	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3885|KRT34, HA4, Ha-4, KRTHA4, hHa4; keratin 34; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cuticular Ha4 GN=KRT34 OS=Homo sapiens (Human) PE=2 SV=2"	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: keratin, type I cuticular Ha4 [Oryctolagus cuniculus]"
ENSG00000131738(KRT33B)	--	0.0316548	1	0	0	0	0	0.0626056	2	0.0921361	2	0.0311771	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3884|KRT33B, HA3II, Ha-3II, K33B, KRTHA3A, KRTHA3B, hHa3-II; keratin 33B; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cuticular Ha3-II GN=KRT33B OS=Homo sapiens (Human) PE=2 SV=3"	Z	Cytoskeleton	"PREDICTED: keratin, type I cuticular Ha3-I-like [Ochotona princeps]"
ENSG00000131746(TNS4)	--	6.62069	648	3.110832	262	4.43988	417	80.8555	7993	88.7166	8929	63.63466	6780	0	3.590739095	up	0	5.061437521	up	0	4.009989606	up	4.36E-60	4.137241372	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K18080|0|hsa:84951|TNS4, CTEN; tensin 4; K18080 tensin (A)"	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Phosphotyrosine-binding domain;; SH2 domain	Tensin-4 (Precursor) GN=TNS4 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: tensin-4 [Loxodonta africana]
ENSG00000131747(TOP2A)	--	141.6980022	17213	131.6320025	15820	148.9390025	17647	142.867633	17434	128.0710027	15501	119.8041842	14501	0.997645818	-0.012426109	normal	0.997163513	-0.050809961	normal	0.984623945	-0.291534387	normal	0.642201639	-0.117063235	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase type II (ATP-hydrolyzing) activity (GO:0003918);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA topological change (GO:0006265);; 	"K03164|0|hsa:7153|TOP2A, TOP2, TP2A; topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3); K03164 DNA topoisomerase II [EC:5.99.1.3] (A)"	--	[B]	Chromatin structure and dynamics	"DNA gyrase/topoisomerase IV, subunit A;; DNA gyrase B;; DTHCT (NUC029) region;; Toprim domain;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	DNA topoisomerase 2-alpha GN=TOP2A OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: DNA topoisomerase 2-alpha [Galeopterus variegatus]
ENSG00000131748(STARD3)	--	29.5944892	1033	26.74421128	947	28.25826844	1047	31.12945818	1110	32.20724658	1141	32.78121044	1187	0.9783493	0.072782719	normal	0.941297648	0.247076016	normal	0.967144287	0.172532863	normal	0.427757343	0.162817323	normal	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[I]	Lipid transport and metabolism	Cholesterol-capturing domain;; START domain	StAR-related lipid transfer protein 3 GN=STARD3 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: stAR-related lipid transfer protein 3 isoform 1 [Trichechus manatus latirostris]
ENSG00000131759(RARA)	--	14.26557517	897	16.97345003	974	13.44665292	855	14.38016946	885	13.24213756	825	13.84442903	926	0.977217871	-0.050176266	normal	0.930563504	-0.260514124	normal	0.973463551	0.106615088	normal	0.793203414	-0.069699104	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08527|0|mdo:100015353|RARA; retinoic acid receptor, alpha; K08527 retinoic acid receptor alpha (A)"	Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Acute myeloid leukemia (ko05221)	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Retinoic acid receptor alpha GN=RARA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: retinoic acid receptor alpha isoform 1 [Odobenus rosmarus divergens]
ENSG00000131771(PPP1R1B)	--	0	0	0.072079959	2	0.053717987	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein phosphatase inhibitor activity (GO:0004864);; Biological Process: signal transduction (GO:0007165);; 	K15494|1.09366e-103|ggo:101139296|PPP1R1B; protein phosphatase 1 regulatory subunit 1B isoform 1; K15494 protein phosphatase 1 regulatory subunit 1B (A)	cAMP signaling pathway (ko04024);; Dopaminergic synapse (ko04728);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)	--	--	Protein phosphatase inhibitor 1/DARPP-32	Protein phosphatase 1 regulatory subunit 1B GN=PPP1R1B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 1B [Orcinus orca]
ENSG00000131773(KHDRBS3)	--	0.992828117	38	1.152282026	29	1.087276706	40	1.515467002	57	1.369501184	52	0.779083338	30	0.928190313	0.536323084	normal	0.807020238	0.789887047	normal	0.969445043	-0.405565402	normal	0.607456448	0.354978429	normal	[A]	RNA processing and modification	Molecular Function: RNA binding (GO:0003723);; 	"K14942|0|ptr:464413|KHDRBS3; KH domain containing, RNA binding, signal transduction associated 3; K14942 KH domain-containing, RNA-binding, signal transduction-associated protein 3 (A)"	--	[A]	RNA processing and modification	--	"KH domain-containing, RNA-binding, signal transduction-associated protein 3 GN=KHDRBS3 OS=Homo sapiens (Human) PE=1 SV=1"	A	RNA processing and modification	"PREDICTED: KH domain-containing, RNA-binding, signal transduction-associated protein 3 [Odobenus rosmarus divergens]"
ENSG00000131778(CHD1L)	--	20.56221778	1246	19.58282338	1201	19.74936137	1174	19.75853697	1191	19.83528822	1163	18.36002901	1107	0.978430416	-0.09584202	normal	0.97940862	-0.067724946	normal	0.977873578	-0.09294531	normal	0.719950803	-0.086665824	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[K]	Transcription	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; Class II histone deacetylase complex subunits 2 and 3;; DEAD/DEAH box helicase"	Chromodomain-helicase-DNA-binding protein 1-like GN=CHD1L OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: chromodomain-helicase-DNA-binding protein 1-like [Galeopterus variegatus]
ENSG00000131779(PEX11B)	--	12.35510482	310	12.42029388	323	12.44072431	320	16.36544197	425	16.09624364	408	12.26413861	314	0.702187594	0.422567323	normal	0.882206299	0.314296562	normal	0.967633651	-0.035429755	normal	0.353497208	0.245306617	normal	--	--	Cellular Component: integral component of peroxisomal membrane (GO:0005779);; Biological Process: peroxisome fission (GO:0016559);; 	K13352|1.50252e-139|ggo:101135235|PEX11B; peroxisomal membrane protein 11B isoform 1; K13352 peroxin-11B (A)	Peroxisome (ko04146)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Peroxisomal biogenesis factor 11 (PEX11)	Peroxisomal membrane protein 11B GN=PEX11B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein 11B isoform 1 [Ceratotherium simum simum]
ENSG00000131781(FMO5)	--	0.462665601	12	0.40770325	6	0.120076001	4	0.603153285	22	0.5741279	25	0.653082869	29	0.969604704	0.7699705	normal	0.356997995	1.800679255	normal	0.012092652	2.461718903	normal	0.006860043	1.767097469	up	[P]	Inorganic ion transport and metabolism	"Molecular Function: N,N-dimethylaniline monooxygenase activity (GO:0004499);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00485|0|ptr:469472|FMO5; flavin containing monooxygenase 5; K00485 dimethylaniline monooxygenase (N-oxide forming) [EC:1.14.13.8] (A)	Drug metabolism - cytochrome P450 (ko00982)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Flavin-binding monooxygenase-like;; Pyridine nucleotide-disulphide oxidoreductase;; L-lysine 6-monooxygenase (NADPH-requiring);; Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain	Dimethylaniline monooxygenase [N-oxide-forming] 5 GN=FMO5 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dimethylaniline monooxygenase [N-oxide-forming] 5 isoform X1 [Tupaia chinensis] 
ENSG00000131788(PIAS3)	--	22.22940073	877	19.85655197	728	19.10680846	788	14.648265	610	17.06251054	677	12.96237664	529	0.167999919	-0.553430203	normal	0.96745536	-0.125937807	normal	0.113789593	-0.581847235	normal	0.016871125	-0.419554601	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K16064|0|hsa:10401|PIAS3, ZMIZ5; protein inhibitor of activated STAT, 3; K16064 E3 SUMO-protein ligase PIAS3 [EC:6.3.2.-] (A)"	Ubiquitin mediated proteolysis (ko04120);; Jak-STAT signaling pathway (ko04630)	[K]	Transcription	PINIT domain;; MIZ/SP-RING zinc finger;; Zinc-finger of the MIZ type in Nse subunit	E3 SUMO-protein ligase PIAS3 GN=PIAS3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: E3 SUMO-protein ligase PIAS3 isoform X1 [Tupaia chinensis]
ENSG00000131791(PRKAB2)	--	6.277071799	544	5.126629499	437	5.731591	487	8.72824449	768	7.5784498	652	5.8490958	515	0.496437179	0.46555598	normal	0.215947206	0.55423227	normal	0.969496782	0.072141349	normal	0.173109132	0.37613921	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K07199|0|hsa:5565|PRKAB2; protein kinase, AMP-activated, beta 2 non-catalytic subunit; K07199 5'-AMP-activated protein kinase, regulatory beta subunit (A)"	FoxO signaling pathway (ko04068);; AMPK signaling pathway (ko04152);; Circadian rhythm (ko04710);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Oxytocin signaling pathway (ko04921);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hypertrophic cardiomyopathy (HCM) (ko05410)	[G]	Carbohydrate transport and metabolism	"5'-AMP-activated protein kinase beta subunit, interation domain"	5'-AMP-activated protein kinase subunit beta-2 GN=PRKAB2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	5'-AMP-activated protein kinase subunit beta-2 [Bos taurus] 
ENSG00000131828(PDHA1)	--	51.17962314	2212	42.39354425	2165	58.36475608	2392	57.14492375	2288	55.99478927	2324	45.65247906	2175	0.987852607	0.017891184	normal	0.985919273	0.080762031	normal	0.981868118	-0.14539699	normal	0.956980171	-0.01731976	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624);; "	K00161|0|mcf:102125852|PDHA1; pyruvate dehydrogenase (lipoamide) alpha 1; K00161 pyruvate dehydrogenase E1 component alpha subunit [EC:1.2.4.1] (A)	Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; HIF-1 signaling pathway (ko04066);; Central carbon metabolism in cancer (ko05230)	[C]	Energy production and conversion	Dehydrogenase E1 component	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (Precursor) GN=PDHA1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X1 [Mustela putorius furo]"
ENSG00000131831(RAI2)	--	0.025684278	1	0.025823368	1	0.022580327	0	0.069824112	3	0.156854278	6	0.101328216	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sine oculis-binding protein	Retinoic acid-induced protein 2 GN=RAI2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: retinoic acid-induced protein 2 isoform 3 [Ceratotherium simum simum]
ENSG00000131844(MCCC2)	--	33.2425351	1865	33.8622208	1898	33.40707235	1919	38.22096796	2228	38.27673231	2195	35.31207632	2031	0.965200418	0.22557115	normal	0.974058757	0.188174873	normal	0.985296581	0.073487787	normal	0.401274226	0.162377285	normal	[I]	Lipid transport and metabolism	--	"K01969|0|hsa:64087|MCCC2, MCCB; methylcrotonoyl-CoA carboxylase 2 (beta) (EC:6.4.1.4); K01969 3-methylcrotonyl-CoA carboxylase beta subunit [EC:6.4.1.4] (A)"	"Valine, leucine and isoleucine degradation (ko00280)"	[EI]	Amino acid transport and metabolism;; Lipid transport and metabolism	Carboxyl transferase domain	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial (Precursor) GN=MCCC2 OS=Homo sapiens (Human) PE=1 SV=1"	EI	Amino acid transport and metabolism;; Lipid transport and metabolism	"PREDICTED: methylcrotonoyl-CoA carboxylase beta chain, mitochondrial [Elephantulus edwardii]"
ENSG00000131845(ZNF304)	--	3.188344196	255	3.118122427	256	3.023341066	236	3.533295808	280	2.78907109	223	4.2069237	333	0.962636167	0.103502072	normal	0.94055808	-0.219138348	normal	0.570630765	0.485810749	normal	0.688186111	0.141501083	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:57343|ZNF304; zinc finger protein 304; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 304 GN=ZNF304 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 304-like [Equus przewalskii]
ENSG00000131848(ZSCAN5A)	--	6.989735	115	2.948896234	87	4.840919033	81	2.743661005	58	2.87049465	58	3.582111	63	0.036846959	-0.999167032	normal	0.802557898	-0.593661452	normal	0.943158168	-0.363153276	normal	0.108306967	-0.682108947	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:79149|ZSCAN5A, ZNF495, ZSCAN5; zinc finger and SCAN domain containing 5A; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger and SCAN domain-containing protein 5A GN=ZSCAN5A OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 5B-like isoform X2 [Equus przewalskii]
ENSG00000131849(ZNF132)	--	0.862025007	52	1.31671863	77	0.802036761	48	1.350710655	77	1.012766477	59	1.137425741	67	0.893933887	0.522752436	normal	0.935513849	-0.396642801	normal	0.932293682	0.460502837	normal	0.798793363	0.175409223	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7691|ZNF132, pHZ-12; zinc finger protein 132; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 132 GN=ZNF132 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 132-like [Galeopterus variegatus]
ENSG00000131864(USP29)	--	0	0	0	0	0	0	0	0	0	0	0.014300666	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11850|0|hsa:57663|USP29, HOM-TES-84/86; ubiquitin specific peptidase 29 (EC:3.4.19.12); K11850 ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 29 GN=USP29 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 29 [Ceratotherium simum simum]
ENSG00000131871(SELENOS)	--	39.9775617	763	37.10786572	717	38.364672	742	40.01592084	770	38.3870193	723	49.64529907	942	0.97632004	-0.017621553	normal	0.975133722	-0.009384319	normal	0.854991246	0.335408356	normal	0.652838342	0.111462086	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Cellular Component: integral component of endoplasmic reticulum membrane (GO:0030176);; 	"K14025|5.09786e-74|hsa:55829|VIMP, ADO15, SBBI8, SELS, SEPS1; VCP-interacting membrane protein; K14025 selenoprotein S (A)"	Protein processing in endoplasmic reticulum (ko04141)	--	--	Selenoprotein S (SelS)	Selenoprotein S GN=VIMP OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: selenoprotein S [Ovis aries]
ENSG00000131873(CHSY1)	--	13.40010827	1005	15.38179475	1168	13.79321701	1059	14.637451	1107	12.23672871	940	11.47857719	855	0.975455712	0.108469422	normal	0.866505424	-0.334250687	normal	0.883363453	-0.316493698	normal	0.38177421	-0.177459004	normal	--	--	"Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; Cellular Component: Golgi cisterna membrane (GO:0032580);; "	"K13499|0|hsa:22856|CHSY1, CHSY, CSS1, ChSy-1, TPBS; chondroitin sulfate synthase 1 (EC:2.4.1.175 2.4.1.226); K13499 chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[G]	Carbohydrate transport and metabolism	Chondroitin N-acetylgalactosaminyltransferase;; Fringe-like;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Chondroitin sulfate synthase 1 GN=CHSY1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: chondroitin sulfate synthase 1 [Loxodonta africana]
ENSG00000131876(SNRPA1)	--	54.43323228	925	47.10654059	797	56.30939579	959	50.03214062	840	51.33914851	862	42.97872755	725	0.963774723	-0.169600521	normal	0.973330976	0.091514592	normal	0.684101452	-0.411093156	normal	0.444706358	-0.164940839	normal	[S]	Function unknown	--	K11092|2.39177e-174|ptr:453692|SNRPA1; small nuclear ribonucleoprotein polypeptide A'; K11092 U2 small nuclear ribonucleoprotein A' (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	Leucine-rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeat	U2 small nuclear ribonucleoprotein A' GN=SNRPA1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U2 small nuclear ribonucleoprotein A' [Orycteropus afer afer]
ENSG00000131899(LLGL1)	--	14.33230905	1174	12.9068	1066	13.4748	1124	12.929	1048	15.585547	1261	14.0483	1151	0.961840307	-0.194356544	normal	0.954707058	0.220646204	normal	0.980847964	0.025919893	normal	0.954699822	0.019778892	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06094|0|hsa:3996|LLGL1, DLG4, HUGL, HUGL-1, HUGL1, LLGL; lethal giant larvae homolog 1 (Drosophila); K06094 lethal(2) giant larvae protein (A)"	Hippo signaling pathway (ko04390);; Tight junction (ko04530)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"LLGL2;; WD domain, G-beta repeat;; Lethal giant larvae(Lgl) like, C-terminal"	Lethal(2) giant larvae protein homolog 1 GN=LLGL1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: lethal(2) giant larvae protein homolog 1 isoform X2 [Canis lupus familiaris] 
ENSG00000131910(NR0B2)	--	0.059141	1	0	0	0	0	0	0	0.057505	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; "	"K08563|1.00791e-165|hsa:8431|NR0B2, SHP, SHP1; nuclear receptor subfamily 0, group B, member 2; K08563 nuclear receptor subfamily 0 group B member 2 (A)"	Bile secretion (ko04976)	[T]	Signal transduction mechanisms	Ligand-binding domain of nuclear hormone receptor	Nuclear receptor subfamily 0 group B member 2 GN=NR0B2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor subfamily 0 group B member 2 [Leptonychotes weddellii]
ENSG00000131914(LIN28A)	--	0	0	0.064649456	4	0	0	0.016338633	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	"K18754|4.9981e-132|hsa:79727|LIN28A, CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A; lin-28 homolog A (C. elegans); K18754 protein lin-28 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	'Cold-shock' DNA-binding domain;; Zinc knuckle	Protein lin-28 homolog A GN=LIN28A OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: protein lin-28 homolog A [Oryctolagus cuniculus] 
ENSG00000131931(THAP1)	--	6.88242377	215	7.032946902	213	6.473962146	201	7.286798	233	7.023039071	219	6.984809004	220	0.964115693	0.084580352	normal	0.965703525	0.018521198	normal	0.961024928	0.121145101	normal	0.871830381	0.073913685	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 1 GN=THAP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: THAP domain-containing protein 1 [Galeopterus variegatus]
ENSG00000131941(RHPN2)	--	51.7098	3276	49.5951	3152	50.4927	3199	40.1678	2556	39.9114	2519	41.3051	2625	0.820779267	-0.388672796	normal	0.900773358	-0.344657559	normal	0.944918887	-0.29344161	normal	0.029738633	-0.343344392	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[R]	General function prediction only	BRO1-like domain;; Hr1 repeat	Rhophilin-2 GN=RHPN2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rhophilin-2 [Felis catus]
ENSG00000131943(C19orf12)	--	24.98040596	1044	26.89171842	1042	28.33088898	1071	26.40804164	1035	26.70038958	1052	26.26901595	1009	0.979309592	-0.043259267	normal	0.979605579	-0.007636101	normal	0.976602436	-0.094186704	normal	0.858931685	-0.049347855	normal	--	--	--	--	--	--	--	--	Protein C19orf12 GN=C19orf12 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein C19orf12 homolog [Ceratotherium simum simum]
ENSG00000131944(FAAP24)	--	11.36651529	325	9.21684544	379	10.61067591	334	6.71532279	250	7.690245131	236	9.595310826	281	0.766782325	-0.407142093	normal	0.042483687	-0.701256653	normal	0.924910766	-0.256302549	normal	0.050972672	-0.457505355	normal	--	--	--	"K10898|5.2836e-153|nle:100583774|C10H19orf40; chromosome 10 open reading frame, human C19orf40; K10898 fanconi anemia-associated protein (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	Helix-hairpin-helix motif	Fanconi anemia-associated protein of 24 kDa GN=FAAP24 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	Fanconi anemia-associated protein of 24 kDa [Bos taurus] 
ENSG00000131966(ACTR10)	--	18.59926404	628	18.405779	598	20.32217304	661	20.88252676	714	21.3355351	670	23.103897	719	0.962815127	0.153973803	normal	0.96363972	0.142249068	normal	0.969472343	0.112802544	normal	0.581062896	0.135305224	normal	[Z]	Cytoskeleton	--	"K16576|0|hsa:55860|ACTR10, ACTR11, Arp11, HARP11; actin-related protein 10 homolog (S. cerevisiae); K16576 actin-related protein 10 (A)"	--	[Z]	Cytoskeleton	Actin	Actin-related protein 10 GN=ACTR10 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: actin-related protein 10 [Felis catus]
ENSG00000131969(ABHD12B)	--	0.043169402	1	0.0844431	2	0.126684	2	0.213441	5	0.0420721	0	0.171798	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Molecular Function: hydrolase activity (GO:0016787);; 	"K13705|0|hsa:145447|ABHD12B, BEM46L3, C14orf29, c14_5314; abhydrolase domain containing 12B; K13705 abhydrolase domain-containing protein 12B (A)"	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Putative lysophospholipase;; Prolyl oligopeptidase family;; X-Pro dipeptidyl-peptidase (S15 family);; Secretory lipase	Abhydrolase domain-containing protein 12B GN=ABHD12B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: abhydrolase domain-containing protein 12B [Pteropus alecto]
ENSG00000131979(GCH1)	--	3.09840749	128	2.275706313	92	2.314995	95	4.86234938	191	4.34262918	169	4.43731674	174	0.607177573	0.541246986	normal	0.053588574	0.845489554	normal	0.04006189	0.854596733	normal	0.016173016	0.739790054	normal	[H]	Coenzyme transport and metabolism	--	K01495|2.08987e-175|ptr:743728|GCH1; GTP cyclohydrolase 1; K01495 GTP cyclohydrolase I [EC:3.5.4.16] (A)	Folate biosynthesis (ko00790)	[H]	Coenzyme transport and metabolism	GTP cyclohydrolase I	GTP cyclohydrolase 1 GN=GCH1 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: GTP cyclohydrolase 1 [Loxodonta africana]
ENSG00000131981(LGALS3)	--	31.73624	483	29.34138	433	33.41125	525	66.30476	1035	58.19803	911	57.50551	938	1.86E-07	1.06633317	up	7.79E-07	1.049075489	up	0.000352867	0.827171967	normal	1.42E-10	0.979740323	normal	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	"K06831|3.73727e-94|pon:100453870|LGALS3; lectin, galactoside-binding, soluble, 3; K06831 galectin-3 (A)"	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-3 GN=LGALS3 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: galectin-3 [Dasypus novemcinctus]
ENSG00000132000(PODNL1)	--	0.94183883	18	0.450671352	8	0.891951012	7	0.581481677	13	0.2693757	3	0.317766739	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat	Podocan-like protein 1 (Precursor) GN=PODNL1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: podocan-like protein 1 [Eptesicus fuscus]
ENSG00000132002(DNAJB1)	--	57.53473815	2384	70.70929955	2973	77.05978792	3215	88.65140215	3745	78.02216893	3275	66.47199566	2790	0.040260681	0.620427738	normal	0.987164236	0.118091638	normal	0.97575239	-0.21273754	normal	0.545667731	0.172838007	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09507|0|pps:100971940|DNAJB1; DnaJ (Hsp40) homolog, subfamily B, member 1; K09507 DnaJ homolog subfamily B member 1 (A)"	Protein processing in endoplasmic reticulum (ko04141);; Influenza A (ko05164)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain	DnaJ homolog subfamily B member 1 GN=DNAJB1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 1 [Leptonychotes weddellii]
ENSG00000132003(ZSWIM4)	--	3.13992623	291	3.341634657	277	4.527547903	311	3.930398	343	4.862212394	420	5.121727517	444	0.944185049	0.205357652	normal	0.232324951	0.576503755	normal	0.441194127	0.503294998	normal	0.052789651	0.437280595	normal	[S]	Function unknown	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[S]	Function unknown	--	Zinc finger SWIM domain-containing protein 4 GN=ZSWIM4 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger SWIM domain-containing protein 4 isoform X1 [Sus scrofa]
ENSG00000132004(FBXW9)	--	5.568134	164	3.961502	118	4.309700526	131	4.981509	147	5.9645968	176	5.7366643	171	0.954664465	-0.186861611	normal	0.619429403	0.549560203	normal	0.883912043	0.372365192	normal	0.563526495	0.237621464	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10265|0|pon:100442624|FBXW9; F-box and WD repeat domain containing 9; K10265 F-box and WD-40 domain protein 9 (A)	--	--	--	"WD domain, G-beta repeat;; F-box-like;; F-box domain;; PQQ-like domain"	F-box/WD repeat-containing protein 9 GN=FBXW9 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box/WD repeat-containing protein 9 [Ceratotherium simum simum]
ENSG00000132005(RFX1)	--	4.0916957	303	4.8112383	361	4.158567854	347	3.543239136	303	4.621902	358	4.3019005	342	0.967450795	-0.030676711	normal	0.967549316	-0.033325618	normal	0.96831703	-0.029103018	normal	0.941666128	-0.03219321	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09173|0|hsa:5989|RFX1, EFC, RFX; regulatory factor X, 1 (influences HLA class II expression); K09173 regulatory factor X 1/2/3 (A)"	--	[K]	Transcription	RFX1 transcription activation region;; RFX DNA-binding domain	MHC class II regulatory factor RFX1 GN=RFX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: MHC class II regulatory factor RFX1 isoform X1 [Canis lupus familiaris] 
ENSG00000132010(ZNF20)	--	0.899743516	31	0.1934746	11	0.3685691	20	0.1935443	8	0.2385421	13	0.236385388	13	0.135106318	-1.798151986	normal	--	--	--	0.981534541	-0.575453989	normal	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:103785278|ZNF20; zinc finger protein 20; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 20 GN=ZNF20 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 709 [Galeopterus variegatus]
ENSG00000132016(C19orf57)	--	1.018770134	19	0.5515465	18	0.2510622	13	0.193333368	11	0.1697657	3	0.2942575	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C19orf57 GN=C19orf57 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C19orf57 homolog [Galeopterus variegatus]
ENSG00000132017(DCAF15)	--	9.064818002	368	8.380650159	323	8.568775024	368	7.705828	285	8.0402	288	6.943404	276	0.770541964	-0.397683473	normal	0.948505458	-0.185969197	normal	0.722937714	-0.42132257	normal	0.174859629	-0.339993852	normal	--	--	--	"K11791|0|hsa:90379|DCAF15, C19orf72; DDB1 and CUL4 associated factor 15; K11791 DDB1- and CUL4-associated factor 15 (A)"	--	--	--	"DDB1-and CUL4-substrate receptor 15, WD repeat"	DDB1- and CUL4-associated factor 15 GN=DCAF15 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 15 [Condylura cristata]
ENSG00000132024(CC2D1A)	--	9.15092408	753	7.444676656	647	7.531476621	618	8.211674243	655	9.450325604	780	8.899368381	765	0.94035912	-0.231480273	normal	0.932889138	0.247753801	normal	0.895180862	0.298902879	normal	0.689714633	0.103713456	normal	--	--	--	"K18260|0|hsa:54862|CC2D1A, FREUD-1, Freud-1/Aki1, MRT3; coiled-coil and C2 domain containing 1A; K18260 coiled-coil and C2 domain-containing protein 1 (A)"	--	[R]	General function prediction only	C2 domain	Coiled-coil and C2 domain-containing protein 1A GN=CC2D1A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: coiled-coil and C2 domain-containing protein 1A-like isoform X1 [Leptonychotes weddellii]
ENSG00000132026(RTBDN)	--	0.0721351	1	0.214336	3	0.143984823	3	0.266653	2	0.069424	0	0.128058926	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Folate receptor family	Retbindin (Precursor) GN=RTBDN OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: retbindin isoform 2 [Odobenus rosmarus divergens]
ENSG00000132031(MATN3)	--	3.711977	150	3.941984	161	3.464343001	140	2.716924081	110	4.779708612	192	2.486129753	101	0.802215363	-0.472613104	normal	0.941751455	0.230633227	normal	0.817611616	-0.473316457	normal	0.755656779	-0.183616262	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	von Willebrand factor type A domain;; Coagulation Factor Xa inhibitory site;; Trimeric coiled-coil oligomerisation domain of matrilin;; Complement Clr-like EGF-like;; von Willebrand factor type A domain;; Calcium-binding EGF domain;; EGF-like domain	Matrilin-3 (Precursor) GN=MATN3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: matrilin-3 [Balaenoptera acutorostrata scammoni]
ENSG00000132109(TRIM21)	--	6.367513813	266	6.458203126	276	6.555224	280	6.548186475	280	6.897849	289	7.498962649	318	0.966636278	0.042926647	normal	0.965705126	0.044735124	normal	0.952242698	0.17442397	normal	0.816059696	0.089038089	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10651|0|ptr:450975|TRIM21, SSA1; tripartite motif containing 21; K10651 tripartite motif-containing protein 21 [EC:6.3.2.19] (A)"	Systemic lupus erythematosus (ko05322)	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; zinc-RING finger domain;; RING-type zinc-finger;; Zinc-finger of the MIZ type in Nse subunit"	E3 ubiquitin-protein ligase TRIM21 GN=TRIM21 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM21 [Galeopterus variegatus]
ENSG00000132122(SPATA6)	--	2.635956185	109	2.511040216	98	1.544432033	72	0.925216203	58	2.147342654	97	1.138147585	56	0.104256438	-0.922896934	normal	0.969515624	-0.035670284	normal	0.949608061	-0.362212335	normal	0.384006779	-0.424591757	normal	--	--	--	--	--	--	--	Spermatogenesis-assoc protein 6	Spermatogenesis-associated protein 6 (Precursor) GN=SPATA6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: spermatogenesis-associated protein 6 isoform X1 [Pantholops hodgsonii]
ENSG00000132128(LRRC41)	--	18.2641601	981	18.132962	977	18.34127603	1003	20.45250732	1066	24.65151526	1274	20.68191629	1106	0.976713091	0.088916523	normal	0.825800279	0.361017625	normal	0.97282941	0.132547953	normal	0.308236705	0.197885858	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10347|0|hsa:10489|LRRC41, MUF1; leucine rich repeat containing 41; K10347 leucine-rich repeat-containing protein 41 (A)"	--	--	--	--	Leucine-rich repeat-containing protein 41 GN=LRRC41 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 41 [Odobenus rosmarus divergens]
ENSG00000132141(CCT6B)	--	1.284644	30	0.6970541	21	0.8772084	22	0.9726818	27	0.9987813	22	1.5182229	46	0.984317949	-0.173465489	normal	0.987382267	0.042684417	normal	0.6482758	1.006992909	normal	0.659045708	0.360271241	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09498|0|ptr:468211|CCT6B; chaperonin containing TCP1, subunit 6B (zeta 2); K09498 T-complex protein 1 subunit zeta (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit zeta-2 GN=CCT6B OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: T-complex protein 1 subunit zeta-2 isoform 1 [Dasypus novemcinctus]
ENSG00000132153(DHX30)	--	23.67163439	1865	22.41820669	1829	25.13974	1989	19.8295159	1567	24.1010108	1878	21.239142	1668	0.934486442	-0.281749096	normal	0.985732101	0.016701802	normal	0.948166836	-0.261997603	normal	0.36215843	-0.173271992	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	K13185|0|ptr:461011|DHX30; DEAH (Asp-Glu-Ala-His) box helicase 30; K13185 ATP-dependent RNA helicase DHX30 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; Double-stranded RNA binding motif;; DEAD/DEAH box helicase;; Oligonucleotide/oligosaccharide-binding (OB)-fold	Putative ATP-dependent RNA helicase DHX30 GN=DHX30 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: putative ATP-dependent RNA helicase DHX30 isoform 3 [Odobenus rosmarus divergens] 
ENSG00000132155(RAF1)	--	27.842869	1758	27.43776005	1766	29.895043	1882	25.82167371	1615	26.30811	1670	30.000953	1885	0.976852758	-0.153093511	normal	0.981851576	-0.101973983	normal	0.986322172	-0.005988738	normal	0.713277133	-0.085008009	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: receptor signaling protein activity (GO:0005057);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	K04366|0|bacu:103014337|RAF1; v-raf-1 murine leukemia viral oncogene homolog 1; K04366 RAF proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Alcoholism (ko05034);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Raf-like Ras-binding domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Kinase-like	RAF proto-oncogene serine/threonine-protein kinase GN=RAF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: RAF proto-oncogene serine/threonine-protein kinase isoform X1 [Camelus bactrianus]
ENSG00000132164(SLC6A11)	--	0	0	0.0459242	2	0.0230558	0	0.0138415	1	0	0	0.0137386	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05039|0|hsa:6538|SLC6A11, GAT-3, GAT3, GAT4; solute carrier family 6 (neurotransmitter transporter), member 11; K05039 solute carrier family 6 (neurotransmitter transporter, GABA) member 6/8/11/12/13 (A)"	GABAergic synapse (ko04727)	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium- and chloride-dependent GABA transporter 3 GN=SLC6A11 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium- and chloride-dependent GABA transporter 3 [Orcinus orca]
ENSG00000132170(PPARG)	--	31.42553695	974	27.60982624	889	28.56192554	939	30.15813956	901	27.59053009	899	34.68060215	1007	0.969546889	-0.142992318	normal	0.977743961	-0.00527993	normal	0.975883624	0.092431405	normal	0.957559452	-0.018262124	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08530|0|mcc:574190|PPARG, PPARGAMMA; peroxisome proliferator-activated receptor gamma; K08530 peroxisome proliferator-activated receptor gamma (A)"	PPAR signaling pathway (ko03320);; AMPK signaling pathway (ko04152);; Osteoclast differentiation (ko04380);; Huntington's disease (ko05016);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Thyroid cancer (ko05216)	[T]	Signal transduction mechanisms	"PPAR gamma N-terminal region;; Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Peroxisome proliferator-activated receptor gamma GN=PPARG OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	peroxisome proliferator-activated receptor gamma [Canis lupus familiaris] 
ENSG00000132182(NUP210)	--	52.3986	7721	48.199	7151	48.8358	7269	42.804	6267	45.5268	6677	43.4885	6422	0.951239966	-0.331771544	normal	0.99294971	-0.120345176	normal	0.989350195	-0.186984266	normal	0.264088999	-0.214304238	normal	--	--	--	"K14314|0|hsa:23225|NUP210, GP210, POM210; nucleoporin 210kDa; K14314 nuclear pore complex protein Nup210 (A)"	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Bacterial Ig-like domain (group 2)	Nuclear pore membrane glycoprotein 210 (Precursor) GN=NUP210 OS=Homo sapiens (Human) PE=1 SV=3	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear pore membrane glycoprotein 210 isoform X1 [Pteropus alecto]
ENSG00000132185(FCRLA)	--	0	0	0	0	0	0	0.028565133	1	0.040060185	0	0.097434829	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	Fc receptor-like A (Precursor) GN=UNQ291/PRO329 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: Fc receptor-like A [Balaenoptera acutorostrata scammoni]
ENSG00000132196(HSD17B7)	--	25.611283	430	27.15549	456	29.378483	488	12.031807	217	11.89566	217	22.719943	396	3.05E-05	-1.012277393	down	4.44E-06	-1.087413077	down	0.884362354	-0.30860848	normal	0.015301127	-0.746404658	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K13373|0|hsa:51478|HSD17B7, PRAP, SDR37C1; hydroxysteroid (17-beta) dehydrogenase 7 (EC:1.1.1.62 1.1.1.270); K13373 17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270] (A)"	Steroid biosynthesis (ko00100);; Steroid hormone biosynthesis (ko00140);; Ovarian steroidogenesis (ko04913)	[I]	Lipid transport and metabolism	short chain dehydrogenase;; KR domain;; NAD dependent epimerase/dehydratase family	3-keto-steroid reductase GN=HSD17B7 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 3-keto-steroid reductase isoform X2 [Galeopterus variegatus]
ENSG00000132199(ENOSF1)	--	11.70506141	571	14.7634409	710	11.76661629	538	12.1648118	591	11.60144411	585	14.51486339	725	0.973149571	0.018785438	normal	0.89413909	-0.300103502	normal	0.659457076	0.421060188	normal	0.910957211	0.042666504	normal	[MR]	Cell wall/membrane/envelope biogenesis;; General function prediction only	--	K18334|0|pps:100973408|ENOSF1; enolase superfamily member 1; K18334 L-fuconate dehydratase [EC:4.2.1.68] (A)	Fructose and mannose metabolism (ko00051)	--	--	"Mandelate racemase / muconate lactonizing enzyme, C-terminal domain;; Enolase C-terminal domain-like;; Mandelate racemase / muconate lactonizing enzyme, N-terminal domain;; Collagen triple helix repeat (20 copies)"	Mitochondrial enolase superfamily member 1 GN=ENOSF1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitochondrial enolase superfamily member 1 [Tupaia chinensis]
ENSG00000132205(EMILIN2)	--	5.531672847	215	5.710225358	170	4.176001801	185	5.674957842	211	8.313856137	272	5.8905601	206	0.965702183	-0.057511045	normal	0.17161372	0.652020841	normal	0.958431721	0.145698471	normal	0.456285437	0.252407647	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	EMI domain;; C1q domain	EMILIN-2 (Precursor) GN=EMILIN2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: EMILIN-2 [Tupaia chinensis]
ENSG00000132254(ARFIP2)	--	28.33694108	1111	24.65034123	1017	26.69686865	1042	29.79877543	1201	33.7311978	1373	31.74665127	1259	0.978762299	0.08143674	normal	0.705330536	0.411057554	normal	0.933934641	0.264282133	normal	0.155428525	0.252982397	normal	--	--	Molecular Function: protein domain specific binding (GO:0019904);; 	--	--	[T]	Signal transduction mechanisms	Arfaptin-like domain	Arfaptin-2 GN=ARFIP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: arfaptin-2 isoform X1 [Elephantulus edwardii]
ENSG00000132256(TRIM5)	--	9.613359	487	9.767467685	510	10.441991	491	8.802651	442	9.299410653	482	10.65739963	564	0.955164893	-0.170143906	normal	0.965987287	-0.10257772	normal	0.951247111	0.191131027	normal	0.959389613	-0.020491057	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10648|0|hsa:85363|TRIM5, RNF88, TRIM5alpha; tripartite motif containing 5; K10648 tripartite motif-containing protein 5 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger"	Tripartite motif-containing protein 5 GN=TRIM5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 5-like [Myotis lucifugus]
ENSG00000132259(CNGA4)	--	0.081472472	2	0.0308462	1	0.354771338	8	0.124063742	4	0.079023375	1	0.154705436	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04951|0|hsa:1262|CNGA4, CNCA2, CNG-4, CNG4, CNG5, CNGB2, OCNC2, OCNCBETA, OCNCb; cyclic nucleotide gated channel alpha 4; K04951 cyclic nucleotide gated channel alpha 4 (A)"	cAMP signaling pathway (ko04024);; Olfactory transduction (ko04740)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Cyclic nucleotide-binding domain;; Ion transport protein	Cyclic nucleotide-gated cation channel alpha-4 GN=CNGA4 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: cyclic nucleotide-gated cation channel alpha-4 [Eptesicus fuscus]
ENSG00000132274(TRIM22)	--	1.021936315	25	0.80707602	44	1.398416206	36	3.006013306	150	3.300303482	175	2.848581588	140	1.28E-13	2.483833107	up	2.12E-10	1.934461795	up	8.87E-09	1.907412153	up	1.34E-10	2.125518774	up	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K11999|0|pon:100294624|TRIM22; tripartite motif containing 22; K11999 tripartite motif-containing protein 6/22/34 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; B-box zinc finger;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRIM22 GN=TRIM22 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM22 isoform X1 [Tupaia chinensis] 
ENSG00000132275(RRP8)	--	4.361628	544	5.36453	621	5.664621	567	5.43931	736	5.44984	712	6.485332	685	0.707837916	0.404282006	normal	0.957762126	0.175458134	normal	0.921453072	0.263822729	normal	0.163723338	0.27896629	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Cellular Component: nucleolus (GO:0005730);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K14850|0|hsa:23378|RRP8, KIAA0409, NML; ribosomal RNA processing 8, methyltransferase, homolog (yeast); K14850 ribosomal RNA-processing protein 8 [EC:2.1.1.287] (A)"	--	[A]	RNA processing and modification	Hypothetical methyltransferase;; Methyltransferase domain	Ribosomal RNA-processing protein 8 GN=RRP8 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribosomal RNA-processing protein 8 [Loxodonta africana]
ENSG00000132286(TIMM10B)	--	13.118983	899	13.24215	930	15.2506	919	14.23676	856	12.55396059	886	14.46215	985	0.973686735	-0.101365015	normal	0.97455459	-0.091198617	normal	0.975668381	0.091621765	normal	0.913514069	-0.031835511	normal	--	--	--	"K17779|5.17654e-63|hsa:26515|TIMM10B, FXC1, TIM10B, Tim9b; translocase of inner mitochondrial membrane 10 homolog B (yeast); K17779 mitochondrial import inner membrane translocase subunit TIM10B (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim10/DDP family zinc finger	Mitochondrial import inner membrane translocase subunit Tim10 B GN=TIMM10B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim9 B [Ceratotherium simum simum]
ENSG00000132294(EFR3A)	--	30.44372886	2485	31.00197728	2493	30.9990466	2479	36.5519213	3012	34.13721628	2739	35.20773975	2878	0.965018359	0.246505054	normal	0.985662195	0.114273676	normal	0.975029938	0.206899637	normal	0.307714522	0.189227588	normal	--	--	--	--	--	[R]	General function prediction only	--	Protein EFR3 homolog A GN=EFR3A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein EFR3 homolog A [Ursus maritimus]
ENSG00000132300(PTCD3)	--	22.779305	1952	19.6233614	1886	25.97128561	2051	19.9093736	1694	17.45643472	1670	13.78103559	1397	0.959501122	-0.235152541	normal	0.969925402	-0.196740357	normal	0.127030523	-0.561781833	normal	0.039949998	-0.328348093	normal	--	--	--	"K17659|0|hsa:55037|PTCD3, MRP-S39; pentatricopeptide repeat domain 3; K17659 pentatricopeptide repeat domain-containing protein 3 (A)"	--	[S]	Function unknown	PPR repeat family;; Pentatricopeptide repeat domain;; PPR repeat	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial (Precursor) GN=PTCD3 OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	"PREDICTED: pentatricopeptide repeat domain-containing protein 3, mitochondrial [Pteropus alecto]"
ENSG00000132305(IMMT)	--	66.043887	3842	62.5790241	3621	63.48575448	3692	54.89909471	3184	53.17906491	3097	50.24655505	2932	0.94617861	-0.301716668	normal	0.969588473	-0.24683175	normal	0.910124491	-0.34065195	normal	0.071182906	-0.297383131	normal	--	--	--	"K17785|0|hsa:10989|IMMT, HMP, MINOS2, P87, P87/89, P89, PIG52; inner membrane protein, mitochondrial; K17785 mitofilin (A)"	--	[M]	Cell wall/membrane/envelope biogenesis	Mitochondrial inner membrane protein	MICOS complex subunit MIC60 (Precursor) GN=IMMT OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: mitochondrial inner membrane protein isoform X4 [Tupaia chinensis]
ENSG00000132313(MRPL35)	--	39.30762737	1090	40.60282881	1083	39.76306001	1190	32.27024075	909	26.30848083	830	28.4685315	771	0.908942568	-0.292356174	normal	0.716250256	-0.404629045	normal	0.032060352	-0.633442108	normal	0.005264174	-0.44358945	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02916|4.7581e-125|hsa:51318|MRPL35, L35mt, MRP-L35; mitochondrial ribosomal protein L35; K02916 large subunit ribosomal protein L35 (A)"	Ribosome (ko03010)	[S]	Function unknown	Ribosomal protein L35	"39S ribosomal protein L35, mitochondrial (Precursor) GN=MRPL35 OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L35, mitochondrial [Pteropus alecto]"
ENSG00000132323(ILKAP)	--	16.23482804	427	14.98465677	409	14.398738	389	12.21909415	326	10.86802083	289	10.5343545	281	0.708447158	-0.418467102	normal	0.411306352	-0.520157541	normal	0.564216979	-0.475307521	normal	0.031518739	-0.472998142	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	K17500|0|ptr:746056|ILKAP; integrin-linked kinase-associated serine/threonine phosphatase; K17500 integrin-linked kinase-associated serine/threonine phosphatase 2C [EC:3.1.3.16] (A)	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C;; Protein phosphatase 2C	Integrin-linked kinase-associated serine/threonine phosphatase 2C GN=ILKAP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: integrin-linked kinase-associated serine/threonine phosphatase 2C isoform 1 [Orcinus orca]
ENSG00000132326(PER2)	--	3.492827624	376	4.048074301	428	2.088394281	280	1.766653305	191	1.789067757	239	3.392270215	332	7.52E-05	-1.002130745	down	0.001473591	-0.857910273	normal	0.933783219	0.236291647	normal	0.196993182	-0.528669584	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K02633|0|hsa:8864|PER2, FASPS, FASPS1; period circadian clock 2; K02633 period circadian protein (A)"	Circadian rhythm (ko04710);; Circadian entrainment (ko04713);; Herpes simplex infection (ko05168);; Transcriptional misregulation in cancer (ko05202)	[T]	Signal transduction mechanisms	Period protein 2/3C-terminal region;; PAS domain;; PAS fold;; PAS fold	Period circadian protein homolog 2 GN=PER2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: period circadian protein homolog 2 [Galeopterus variegatus]
ENSG00000132330(SCLY)	--	14.52392345	571	13.17237262	560	16.94433492	688	9.586648794	364	9.980394506	380	9.18375813	414	0.026661902	-0.678078325	normal	0.168668365	-0.578943306	normal	0.00550299	-0.73895238	normal	0.000165535	-0.671945304	normal	[E]	Amino acid transport and metabolism	--	"K01763|0|hsa:51540|SCLY, SCL, hSCL; selenocysteine lyase (EC:4.4.1.16); K01763 selenocysteine lyase [EC:4.4.1.16] (A)"	Selenocompound metabolism (ko00450)	[E]	Amino acid transport and metabolism	Aminotransferase class-V	Selenocysteine lyase GN=SCLY OS=Homo sapiens (Human) PE=1 SV=4	E	Amino acid transport and metabolism	PREDICTED: selenocysteine lyase [Ceratotherium simum simum]
ENSG00000132334(PTPRE)	--	1.378618086	139	0.761559301	81	1.182149169	120	2.612046585	265	2.6111185	244	3.346415985	334	0.004162934	0.892813481	normal	7.75E-09	1.551950111	up	1.66E-09	1.457042227	up	3.48E-06	1.289730502	up	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18033|0|hsa:5791|PTPRE, HPTPE, PTPE, R-PTP-EPSILON; protein tyrosine phosphatase, receptor type, E (EC:3.1.3.48); K18033 receptor-type tyrosine-protein phosphatase epsilon [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain;; Tyrosine phosphatase family;; Inositol hexakisphosphate"	Receptor-type tyrosine-protein phosphatase epsilon (Precursor) GN=PTPRE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase epsilon isoformX1 [Canis lupus familiaris] 
ENSG00000132341(RAN)	--	284.2761079	8801	297.4893113	9432	282.5619134	8888	342.5196451	10984	318.5084117	10037	294.7257698	9476	0.978252159	0.288786703	normal	0.995618221	0.06825533	normal	0.995317461	0.084114077	normal	0.508742812	0.147549719	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07936|1.9043e-151|tup:102500543|RAN; RAN, member RAS oncogene family; K07936 GTP-binding nuclear protein Ran (A)"	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family	GTP-binding nuclear protein Ran GN=RAN OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	"GTP-binding nuclear protein Ran, partial [Bos mutus]"
ENSG00000132356(PRKAA1)	--	23.22544824	1664	24.63359311	1750	24.216755	1647	20.62030477	1487	21.65906472	1545	22.97162293	1618	0.968677517	-0.192894505	normal	0.9675406	-0.200989645	normal	0.984605908	-0.033888994	normal	0.483237391	-0.143194864	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07198|0|ptr:471564|PRKAA1; protein kinase, AMP-activated, alpha 1 catalytic subunit; K07198 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11] (A)"	FoxO signaling pathway (ko04068);; Regulation of autophagy (ko04140);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Circadian rhythm (ko04710);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Oxytocin signaling pathway (ko04921);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hypertrophic cardiomyopathy (HCM) (ko05410)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	5'-AMP-activated protein kinase catalytic subunit alpha-1 GN=PRKAA1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: 5'-AMP-activated protein kinase catalytic subunit alpha-1 isoform X1 [Leptonychotes weddellii]
ENSG00000132357(CARD6)	--	2.697970895	234	3.240020383	279	3.298072	261	3.785771012	329	4.781913503	412	5.842124853	508	0.653394601	0.45819894	normal	0.352829467	0.538536606	normal	8.18E-05	0.948476729	normal	0.025235844	0.670483387	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K12797|0|hsa:84674|CARD6, CINCIN1; caspase recruitment domain family, member 6; K12797 caspase recruitment domain-containing protein 6 (A)"	NOD-like receptor signaling pathway (ko04621)	--	--	Caspase recruitment domain	Caspase recruitment domain-containing protein 6 GN=CARD6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: caspase recruitment domain-containing protein 6 [Ceratotherium simum simum]
ENSG00000132359(RAP1GAP2)	--	7.04608579	1000	6.588147007	947	6.141667055	896	3.671191989	521	3.456761081	492	3.159752233	437	4.33E-06	-0.969374592	normal	8.93E-06	-0.963957103	normal	6.40E-07	-1.041584579	down	7.98E-11	-0.993198113	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	K17708|0|cjc:100393514|RAP1GAP2; RAP1 GTPase activating protein 2; K17708 RAP1 GTPase activating protein 2 (A)	--	[T]	Signal transduction mechanisms	Rap/ran-GAP	Rap1 GTPase-activating protein 2 GN=RAP1GAP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rap1 GTPase-activating protein 2 isoform X2 [Oryctolagus cuniculus]
ENSG00000132361(CLUH)	--	42.9559514	4400	40.08758919	4372	40.54610039	4522	46.48869112	4973	48.34016484	5113	43.20814693	4667	0.989269087	0.145732758	normal	0.98365701	0.20438464	normal	0.992750028	0.037230777	normal	0.54782169	0.128944293	normal	--	--	--	"K03255|0|hsa:23277|CLUH, CLU1, KIAA0664; clustered mitochondria (cluA/CLU1) homolog; K03255 protein TIF31 (A)"	--	[R]	General function prediction only	"Clustered mitochondria;; Translation initiation factor eIF3 subunit 135;; Mitochondrial function, CLU-N-term;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Clustered mitochondria protein homolog {ECO:0000255|HAMAP-Rule:MF_03013} GN=CLUH OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: clustered mitochondria protein homolog [Oryctolagus cuniculus]
ENSG00000132376(INPP5K)	--	12.19182668	693	12.02929612	669	11.30463607	621	13.09180153	727	11.42078548	668	14.67577774	819	0.974944114	0.038185092	normal	0.974063482	-0.023531434	normal	0.74444438	0.390148894	normal	0.567542048	0.13794122	normal	--	--	--	"K01106|0|pps:100976910|INPP5K; inositol polyphosphate-5-phosphatase K; K01106 inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endonuclease/Exonuclease/phosphatase family	Inositol polyphosphate 5-phosphatase K GN=INPP5K OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: inositol polyphosphate 5-phosphatase K isoform X1 [Galeopterus variegatus]
ENSG00000132382(MYBBP1A)	--	27.34275808	2729	27.55322279	2868	31.38563983	3254	30.37242225	2925	30.33106217	2960	25.36290357	2453	0.988752931	0.069194335	normal	0.989606257	0.024113079	normal	0.744921251	-0.415735157	normal	0.623727906	-0.107527679	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K02331|0|hsa:10514|MYBBP1A, P160, PAP2; MYB binding protein (P160) 1a; K02331 DNA polymerase phi [EC:2.7.7.7] (A)"	--	[K]	Transcription	DNA polymerase phi	Myb-binding protein 1A GN=MYBBP1A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: myb-binding protein 1A [Ceratotherium simum simum]
ENSG00000132383(RPA1)	--	55.16685977	3548	55.6663738	3548	61.70695311	3777	56.38423685	3426	49.76346729	3185	46.89167593	2886	0.990040419	-0.0812773	normal	0.982915607	-0.177059493	normal	0.814772354	-0.39627884	normal	0.228216428	-0.21679453	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; 	"K07466|0|hsa:6117|RPA1, HSSB, MST075, REPA1, RF-A, RP-A, RPA70; replication protein A1, 70kDa; K07466 replication factor A1 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	"Replication factor-A C terminal domain;; Replication factor-A protein 1, N-terminal domain;; OB-fold nucleic acid binding domain"	"Replication protein A 70 kDa DNA-binding subunit, N-terminally processed GN=RPA1 OS=Homo sapiens (Human) PE=1 SV=2"	L	"Replication, recombination and repair"	PREDICTED: replication protein A 70 kDa DNA-binding subunit [Galeopterus variegatus]
ENSG00000132386(SERPINF1)	--	0.58145742	17	0.533134958	9	0.8570502	15	0.80313307	21	0.719101108	20	0.733966762	21	0.98799675	0.25339159	normal	0.948856959	1.013952481	normal	0.984457445	0.439539399	normal	0.502541986	0.57582046	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Pigment epithelium-derived factor (Precursor) GN=SERPINF1 OS=Homo sapiens (Human) PE=1 SV=4	V	Defense mechanisms	PREDICTED: pigment epithelium-derived factor isoform X2 [Mustela putorius furo] 
ENSG00000132388(UBE2G1)	--	158.0508716	2908	143.1985001	2687	148.2627577	2771	125.2541744	2615	155.1689626	2697	111.87182	2087	0.979545852	-0.183946032	normal	0.989053226	-0.016058337	normal	0.724565685	-0.417004402	normal	0.276417541	-0.198977074	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10575|1.23489e-110|lve:103069736|UBE2G1; ubiquitin-conjugating enzyme E2G 1; K10575 ubiquitin-conjugating enzyme E2 G1 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	"Ubiquitin-conjugating enzyme E2 G1, N-terminally processed GN=UBE2G1 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 G1 [Echinops telfairi]
ENSG00000132394(EEFSEC)	--	6.058113	267	4.626038	203	5.633297	252	6.037185	266	6.938698	306	5.2805	236	0.966790083	-0.036037992	normal	0.351060365	0.567161874	normal	0.96271637	-0.102293838	normal	0.692392707	0.141115397	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	"Elongation factor Tu GTP binding domain;; Elongation factor Tu domain 2;; 50S ribosome-binding GTPase;; CobW/HypB/UreG, nucleotide-binding domain"	Selenocysteine-specific elongation factor GN=EEFSEC OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: selenocysteine-specific elongation factor [Odobenus rosmarus divergens]
ENSG00000132405(TBC1D14)	--	16.52231321	1406	18.08732669	1546	17.5870616	1546	19.32408931	1661	18.72146104	1529	18.90732149	1592	0.963931416	0.209412494	normal	0.983499966	-0.03734174	normal	0.984194598	0.033975823	normal	0.787087247	0.067047138	normal	[R]	General function prediction only	--	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 14 GN=TBC1D14 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: TBC1 domain family member 14 [Ceratotherium simum simum]
ENSG00000132406(TMEM128)	--	10.08037663	165	8.213719045	132	7.3117277	120	10.5916211	174	10.97688006	182	10.700212	180	0.966688972	0.045377542	normal	0.811042853	0.43768721	normal	0.554173986	0.570759697	normal	0.341105299	0.340800512	normal	--	--	--	--	--	--	--	--	Transmembrane protein 128 GN=TMEM128 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 128 isoform X1 [Equus caballus] 
ENSG00000132423(COQ3)	--	6.214743141	120	5.674325127	113	7.088285	131	7.939148385	161	6.940738341	128	5.861635686	114	0.878732659	0.388882495	normal	0.960674261	0.156426584	normal	0.955578573	-0.20626967	normal	0.813067828	0.124778139	normal	[H]	Coenzyme transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: S-adenosylmethionine-dependent methyltransferase activity (GO:0008757);; Biological Process: oligosaccharide biosynthetic process (GO:0009312);; Biological Process: nodulation (GO:0009877);; 	"K00591|0|hsa:51805|COQ3, DHHBMT, DHHBMTASE, UG0215E05, bA9819.1; coenzyme Q3 methyltransferase (EC:2.1.1.114 2.1.1.64 2.1.1.222); K00591 polyprenyldihydroxybenzoate methyltransferase / 3-demethylubiquinol 3-O-methyltransferase [EC:2.1.1.114 2.1.1.64] (A)"	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130)	[H]	Coenzyme transport and metabolism	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Mycolic acid cyclopropane synthetase;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; Methyltransferase domain;; Methyltransferase small domain;; Ribosomal protein L11 methyltransferase (PrmA);; Nodulation protein S (NodS)	"Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial (Precursor) GN=COQ3 OS=Homo sapiens (Human) PE=1 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: hexaprenyldihydroxybenzoate methyltransferase, mitochondrial [Galeopterus variegatus]"
ENSG00000132424(PNISR)	--	16.62293914	1694	18.512732	1820	16.76694901	1658	15.84666437	1519	15.02000095	1547	16.5066163	1654	0.970110265	-0.187964112	normal	0.949514483	-0.255661097	normal	0.985044577	-0.01176547	normal	0.441741201	-0.152988424	normal	--	--	--	"K13170|0|ptr:472080|PNISR, SFRS18; PNN-interacting serine/arginine-rich protein; K13170 splicing factor, arginine/serine-rich 18 (A)"	--	--	--	--	Arginine/serine-rich protein PNISR OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: arginine/serine-rich protein PNISR isoformX7 [Canis lupus familiaris] 
ENSG00000132429(POPDC3)	--	10.455377	249	9.528249348	241	12.899438	320	9.440005	237	10.06739606	244	7.938658269	200	0.962738976	-0.101449196	normal	0.966014154	-0.003556378	normal	0.07662577	-0.68224689	normal	0.365423975	-0.271390454	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Popeye protein conserved region	Popeye domain-containing protein 3 GN=POPDC3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: popeye domain-containing protein 3 [Galeopterus variegatus]
ENSG00000132432(SEC61G)	--	351.0897748	1155	353.9258282	1194	288.5741017	982	451.1655873	1615	329.5378587	1079	414.902523	1423	0.541294257	0.45229816	normal	0.96811275	-0.167311491	normal	0.232089808	0.526172417	normal	0.340828115	0.283548737	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K07342|2.00696e-28|phi:102101148|SEC61G; Sec61 gamma subunit; K07342 protein transport protein SEC61 subunit gamma and related proteins (A)	Protein export (ko03060);; Protein processing in endoplasmic reticulum (ko04141);; Phagosome (ko04145)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SecE/Sec61-gamma subunits of protein translocation complex	Protein transport protein Sec61 subunit gamma GN=SEC61G OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec61 subunit gamma-like [Bubalus bubalis]
ENSG00000132434(LANCL2)	--	2.519906	171	4.565163	259	3.223406473	165	3.7949	228	4.83359	305	3.99016	246	0.848676245	0.381230238	normal	0.941188594	0.213281976	normal	0.435003027	0.563643043	normal	0.326662251	0.367347007	normal	--	--	--	--	--	[V]	Defense mechanisms	Lanthionine synthetase C-like protein	LanC-like protein 2 GN=LANCL2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: lanC-like protein 2 isoform X2 [Mustela putorius furo] 
ENSG00000132436(FIGNL1)	--	15.38885835	765	14.3248485	767	15.61040347	746	18.45561351	816	13.96957921	686	12.94550416	642	0.975199593	0.062156264	normal	0.95748014	-0.18206474	normal	0.943421	-0.22440291	normal	0.666230489	-0.109469181	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; Vps4 C terminal oligomerisation domain;; Holliday junction DNA helicase ruvB N-terminus	Fidgetin-like protein 1 GN=FIGNL1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: fidgetin-like protein 1 [Galeopterus variegatus] 
ENSG00000132437(DDC)	--	0.0421557	1	0	0	0	0	0.6298354	18	0.612637099	18	0.2053278	7	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: cellular amino acid metabolic process (GO:0006520);; Molecular Function: lyase activity (GO:0016829);; Molecular Function: carboxy-lyase activity (GO:0016831);; Biological Process: carboxylic acid metabolic process (GO:0019752);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K01593|0|hsa:1644|DDC, AADC; dopa decarboxylase (aromatic L-amino acid decarboxylase) (EC:4.1.1.28); K01593 aromatic-L-amino-acid decarboxylase [EC:4.1.1.28] (A)"	Histidine metabolism (ko00340);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Tryptophan metabolism (ko00380);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)	[E]	Amino acid transport and metabolism	Pyridoxal-dependent decarboxylase conserved domain;; Beta-eliminating lyase	Aromatic-L-amino-acid decarboxylase GN=DDC OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: aromatic-L-amino-acid decarboxylase isoform X1 [Condylura cristata]
ENSG00000132463(GRSF1)	--	35.134784	1928	36.02764191	1963	41.470344	2143	44.71243	2327	38.72643439	2125	32.823501	1780	0.961211561	0.240359348	normal	0.984359502	0.092907307	normal	0.942684569	-0.275832147	normal	0.930893469	0.024780393	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	G-rich sequence factor 1 (Precursor) GN=GRSF1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: G-rich sequence factor 1 isoform X1 [Orycteropus afer afer]
ENSG00000132464(ENAM)	--	0	0	0	0	0	0	0.0180801	2	0.0261262	2	0.00889661	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Enamelin	Enamelin (Precursor) GN=ENAM OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: enamelin [Panthera tigris altaica]
ENSG00000132465(JCHAIN)	--	0	0	0	0	0.054381308	0	0	0	0.318695048	2	0.583312011	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin J chain	Immunoglobulin J chain (Precursor) GN=IGJ OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: immunoglobulin J chain [Tupaia chinensis]
ENSG00000132466(ANKRD17)	--	13.09804684	2306	14.0004173	2447	14.207777	2452	14.82340938	2568	15.0599049	2571	15.11215635	2605	0.984491205	0.124341898	normal	0.987966277	0.049858889	normal	0.987435621	0.078985683	normal	0.721808438	0.082980699	normal	[R]	General function prediction only	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	K16726|0|ptr:461263|ANKRD17; ankyrin repeat domain 17; K16726 ankyrin repeat domain-containing protein 17 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; KH domain;; KH domain	Ankyrin repeat domain-containing protein 17 GN=ANKRD17 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ankyrin repeat domain-containing protein 17 [Camelus dromedarius]
ENSG00000132467(UTP3)	--	15.5221	696	15.9295	732	16.1878	736	17.1653	782	16.5173	738	15.5437	695	0.967029402	0.136963698	normal	0.975376917	-0.009629577	normal	0.972122811	-0.090792221	normal	0.975756335	0.012105314	normal	--	--	--	"K14767|0|pon:100459621|UTP3; UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae); K14767 U3 small nucleolar RNA-associated protein 3 (A)"	--	[B]	Chromatin structure and dynamics	Sas10 C-terminal domain;; Sas10/Utp3/C1D family	Something about silencing protein 10 GN=UTP3 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: something about silencing protein 10 [Ceratotherium simum simum]
ENSG00000132470(ITGB4)	--	65.26620414	7824	31.97228193	3977	57.45429544	6899	44.72911933	5299	38.84968166	4556	29.91411452	3502	0.106116875	-0.592876042	normal	0.985867124	0.17459856	normal	3.36E-07	-0.986190258	normal	0.335333434	-0.507426926	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell communication (GO:0007154);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06525|0|hsa:3691|ITGB4, CD104; integrin, beta 4; K06525 integrin beta 4 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; Fibronectin type III domain;; Calx-beta domain;; Integrin beta tail domain;; SEA domain;; EGF-like domain"	Integrin beta-4 (Precursor) GN=ITGB4 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: integrin beta-4 isoform 1 [Odobenus rosmarus divergens]
ENSG00000132471(WBP2)	--	77.77550084	2577	77.75168478	2597	80.38090058	2695	73.34370704	2414	66.12943029	2204	80.7209788	2735	0.984715111	-0.125022088	normal	0.957919056	-0.25798506	normal	0.98943786	0.012956901	normal	0.575552504	-0.118634902	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	WW-domain ligand protein;; GRAM domain	WW domain-binding protein 2 GN=WBP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: WW domain-binding protein 2 isoform X1 [Equus przewalskii]
ENSG00000132475(H3F3B)	--	314.9701282	6364	343.49499	6518	346.6234335	6346	502.5016185	10175	444.7719258	8884	387.8141295	7539	0.034202648	0.646066405	normal	0.837034322	0.425268663	normal	0.983100201	0.240181635	normal	0.008218238	0.445985697	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|3.17643e-60|cin:100183235|histone H3.3; K11253 histone H3 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.3 GN=H3F3B OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	Histone H3.3 [Myotis davidii]
ENSG00000132478(UNK)	--	19.503123	1048	16.268593	830	16.154343	883	16.955213	779	19.61289	886	19.78303	899	0.508752641	-0.457993697	normal	0.975120168	0.072640692	normal	0.978163708	0.017586385	normal	0.577010037	-0.127582061	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	RING finger protein unkempt homolog GN=UNK OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein unkempt homolog isoform X1 [Equus caballus]
ENSG00000132481(TRIM47)	--	41.01370152	1500	32.73568	1201	39.967218	1498	46.50377306	1696	49.13204313	1803	41.337292	1499	0.97696025	0.146200516	normal	0.137932996	0.564153223	normal	0.98405235	-0.007321294	normal	0.193663156	0.230054045	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12023|0|hsa:91107|TRIM47, GOA, RNF100; tripartite motif containing 47; K12023 tripartite motif-containing protein 47 (A)"	--	--	--	"zinc finger of C3HC4-type, RING;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; zinc-RING finger domain;; RING-type zinc-finger;; SPRY-associated domain;; SPRY domain"	Tripartite motif-containing protein 47 GN=TRIM47 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 47 [Ceratotherium simum simum]
ENSG00000132485(ZRANB2)	--	24.02900259	1207	26.17877424	1313	25.57533497	1252	24.36833569	1223	21.65127426	1105	18.04432949	933	0.981720004	-0.011818591	normal	0.932523625	-0.269907746	normal	0.615124227	-0.431970331	normal	0.204100894	-0.232031928	normal	--	--	--	--	--	[R]	General function prediction only	Zn-finger in Ran binding protein and others	Zinc finger Ran-binding domain-containing protein 2 GN=ZRANB2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	Zinc finger Ran-binding domain-containing protein 2 [Pteropus alecto]
ENSG00000132507(EIF5A)	--	596.75444	13853	629.6671801	15071	632.14697	15115	773.30247	18412	671.340093	15497	539.117365	12596	0.948413714	0.379579023	normal	0.997235191	0.018785394	normal	0.986359678	-0.271276983	normal	0.867815531	0.056334682	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation elongation factor activity (GO:0003746);; Biological Process: translational frameshifting (GO:0006452);; Molecular Function: ribosome binding (GO:0043022);; Biological Process: positive regulation of translational elongation (GO:0045901);; Biological Process: positive regulation of translational termination (GO:0045905);; 	K03263|2.24794e-99|myb:102260948|EIF5A; eukaryotic translation initiation factor 5A; K03263 translation initiation factor 5A (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	"Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold"	Eukaryotic translation initiation factor 5A-1 GN=EIF5A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 5A-1 isoform X3 [Mustela putorius furo]
ENSG00000132510(KDM6B)	--	6.07187617	879	5.197722432	745	5.176299032	755	6.190904769	878	7.281623	1041	5.644375561	822	0.977631229	-0.032417793	normal	0.520845984	0.46043716	normal	0.97105094	0.114151119	normal	0.379341815	0.182986084	normal	--	--	--	"K11448|0|hsa:23135|KDM6B, JMJD3; lysine (K)-specific demethylase 6B; K11448 lysine-specific demethylase 6B [EC:1.14.11.-] (A)"	--	[R]	General function prediction only	"JmjC domain, hydroxylase"	Lysine-specific demethylase 6B GN=KDM6B OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: lysine-specific demethylase 6B [Ceratotherium simum simum]
ENSG00000132517(SLC52A1)	--	1.307204973	47	2.558628002	95	3.001149815	110	1.188240869	43	1.090694	39	2.263669	82	0.978299363	-0.153894402	normal	0.004887645	-1.273211854	down	0.895342239	-0.425302444	normal	0.418978174	-0.638236787	normal	--	--	Cellular Component: integral component of plasma membrane (GO:0005887);; Molecular Function: riboflavin transporter activity (GO:0032217);; Biological Process: riboflavin transport (GO:0032218);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1011)	"Solute carrier family 52, riboflavin transporter, member 1 GN=SLC52A1 OS=Homo sapiens (Human) PE=1 SV=2"	P	Inorganic ion transport and metabolism	"PREDICTED: solute carrier family 52, riboflavin transporter, member 2 [Galeopterus variegatus] "
ENSG00000132518(GUCY2D)	--	0.0757547	5	0.0147142	1	0.0849076	5	0	0	0.0144459	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: guanylate cyclase activity (GO:0004383);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: cGMP biosynthetic process (GO:0006182);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12321|0|hsa:3000|GUCY2D, CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC; guanylate cyclase 2D, membrane (retina-specific) (EC:4.6.1.2); K12321 guanylate cyclase 2D/E/F [EC:4.6.1.2] (A)"	Purine metabolism (ko00230);; Olfactory transduction (ko04740);; Phototransduction (ko04744)	[T]	Signal transduction mechanisms	Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein tyrosine kinase;; Protein kinase domain;; Heme NO binding associated	Retinal guanylyl cyclase 1 (Precursor) GN=GUCY2D OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: retinal guanylyl cyclase 1 isoform X1 [Equus przewalskii]
ENSG00000132522(GPS2)	--	39.27186498	1111	38.66452619	1143	42.86311069	1181	44.78974863	1292	42.89188793	1213	41.47772425	1186	0.965164421	0.186675436	normal	0.97952838	0.064245072	normal	0.981525293	-0.002193594	normal	0.732172607	0.082321813	normal	--	--	--	K15307|0|ptr:455229|GPS2; G protein pathway suppressor 2; K15307 G protein pathway suppressor 2 (A)	HTLV-I infection (ko05166)	--	--	--	G protein pathway suppressor 2 GN=GPS2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: G protein pathway suppressor 2 isoform X1 [Condylura cristata]
ENSG00000132530(XAF1)	--	0.012771105	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TRAF-type zinc finger	XIAP-associated factor 1 GN=XAF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: XIAP-associated factor 1 isoform X3 [Camelus bactrianus]
ENSG00000132535(DLG4)	--	11.463934	696	8.686865	536	12.138612	677	5.84145	396	6.2161	386	4.826296	269	0.000424833	-0.841920141	normal	0.449780854	-0.493410284	normal	1.17E-10	-1.334939837	down	4.74E-05	-0.883046685	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11828|0|ptr:468444|DLG4, LLGL1; discs, large homolog 4 (Drosophila); K11828 discs large protein 4 (A)"	Hippo signaling pathway (ko04390);; Glutamatergic synapse (ko04724);; Huntington's disease (ko05016);; Cocaine addiction (ko05030)	[F]	Nucleotide transport and metabolism	Guanylate kinase;; PDZ domain (Also known as DHR or GLGF);; PDZ-associated domain of NMDA receptors;; PDZ domain;; Polyubiquitination (PEST) N-terminal domain of MAGUK;; SH3 domain;; Variant SH3 domain;; L27_1	Disks large homolog 4 GN=DLG4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: disks large homolog 4 isoform X2 [Vicugna pacos]
ENSG00000132541(RIDA)	--	19.74359842	282	18.49270054	270	19.48697242	277	29.33150238	429	24.99335696	357	22.14969022	315	0.227885784	0.571907408	normal	0.80891776	0.379683376	normal	0.951842685	0.176271406	normal	0.108020108	0.387231688	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Endoribonuclease L-PSP	Ribonuclease UK114 GN=HRSP12 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribonuclease UK114 [Panthera tigris altaica]
ENSG00000132549(VPS13B)	--	5.383191584	1364	5.955320119	1398	4.454457	1181	4.686429432	1209	5.291933935	1360	5.90662099	1527	0.961822245	-0.204616652	normal	0.981537225	-0.061117233	normal	0.826267613	0.361990936	normal	0.907178732	0.034168284	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"N-terminal region of Chorein, a TM vesicle-mediated sorter;; Protein of unknown function (DUF1162);; ATG C terminal domain"	Vacuolar protein sorting-associated protein 13B GN=VPS13B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 13B isoform 1 [Ceratotherium simum simum]
ENSG00000132554(RGS22)	--	0.039115701	3	0	0	0.029117597	0	0.115387088	4	0.06315144	4	0.143990104	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Regulator of G protein signaling domain	Regulator of G-protein signaling 22 GN=RGS22 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 22 [Ceratotherium simum simum]
ENSG00000132561(MATN2)	--	3.305735831	273	4.518044088	325	3.245656004	261	5.077111164	411	4.967027791	385	4.264546088	347	0.282547307	0.556835263	normal	0.937808533	0.222041971	normal	0.773962958	0.400574998	normal	0.098764352	0.390129689	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	von Willebrand factor type A domain;; Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; EGF-like domain;; von Willebrand factor type A domain;; Trimeric coiled-coil oligomerisation domain of matrilin;; EGF domain	Matrilin-2 (Precursor) GN=MATN2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: matrilin-2 isoform X1 [Galeopterus variegatus]
ENSG00000132563(REEP2)	--	15.12205352	651	13.41433139	585	15.12382804	667	9.644732006	394	11.418738	486	7.0673668	309	0.004273877	-0.752983883	normal	0.902630465	-0.288088452	normal	2.12E-07	-1.114565589	down	0.000128168	-0.700037816	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K17338|2.62691e-159|ptr:462096|REEP2, C5orf19, SGC32445; receptor accessory protein 2; K17338 receptor expression-enhancing protein 1/2/3/4 (A)"	--	[V]	Defense mechanisms	"TB2/DP1, HVA22 family"	Receptor expression-enhancing protein 2 GN=REEP2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: receptor expression-enhancing protein 2 isoform X1 [Ailuropoda melanoleuca]
ENSG00000132581(SDF2)	--	39.363595	777	49.152261	895	51.733841	920	46.03014	943	44.198055	834	50.838141	1010	0.935964672	0.248065113	normal	0.97070645	-0.123051406	normal	0.972382984	0.126160097	normal	0.742517246	0.083752064	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[R]	General function prediction only	MIR domain	Stromal cell-derived factor 2 (Precursor) GN=SDF2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: stromal cell-derived factor 2 [Galeopterus variegatus]
ENSG00000132589(FLOT2)	--	60.54123749	3306	50.0954526	2844	58.93257098	3280	69.55216337	3861	64.26215096	3494	74.10206452	4124	0.981784478	0.19297252	normal	0.957909826	0.275399267	normal	0.933579068	0.321924431	normal	0.124821348	0.262775462	normal	[S]	Function unknown	--	K07192|0|ptr:454537|FLOT2; flotillin 2; K07192 flotillin (A)	Insulin signaling pathway (ko04910)	[UZ]	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	SPFH domain / Band 7 family	Flotillin-2 GN=FLOT2 OS=Homo sapiens (Human) PE=1 SV=2	UZ	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	hypothetical protein PANDA_000100 [Ailuropoda melanoleuca]
ENSG00000132591(ERAL1)	--	36.146631	1298	36.941458	1330	43.32437	1529	38.140816	1371	42.241552	1470	41.771234	1512	0.982033064	0.048050581	normal	0.977482984	0.122830467	normal	0.984039377	-0.024397443	normal	0.867890036	0.04586222	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	"50S ribosome-binding GTPase;; Miro-like protein;; Dynamin family;; AIG1 family;; Ferrous iron transport protein B;; Elongation factor Tu GTP binding domain;; CobW/HypB/UreG, nucleotide-binding domain;; ADP-ribosylation factor family"	"GTPase Era, mitochondrial (Precursor) GN=ERAL1 OS=Homo sapiens (Human) PE=1 SV=2"	DT	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	"PREDICTED: GTPase Era, mitochondrial [Ceratotherium simum simum]"
ENSG00000132603(NIP7)	--	24.600122	917	23.852885	858	20.060181	740	31.09932	1145	31.933608	1158	23.073713	852	0.912656959	0.289087515	normal	0.70055726	0.410534202	normal	0.955985556	0.194665682	normal	0.207776004	0.304820955	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K07565|8.77238e-133|ptr:454200|NIP7; NIP7, nucleolar pre-rRNA processing protein; K07565 60S ribosome subunit biogenesis protein NIP7 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Uncharacterised protein family (UPF0113)	60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosome subunit biogenesis protein NIP7 homolog isoform 1 [Ceratotherium simum simum] 
ENSG00000132604(TERF2)	--	59.25959291	2192	53.80560202	2059	51.69275693	1970	52.425645	2109	51.46402171	2092	55.57472426	2169	0.985556845	-0.086459176	normal	0.986875484	0.001511363	normal	0.982120692	0.130447514	normal	0.96991704	0.012916888	normal	--	--	Molecular Function: telomeric DNA binding (GO:0042162);; Molecular Function: protein homodimerization activity (GO:0042803);; 	"K11111|0|hsa:7014|TERF2, TRBF2, TRF2; telomeric repeat binding factor 2; K11111 telomeric repeat-binding factor 2 (A)"	--	--	--	Telomere repeat binding factor (TRF);; Myb-like DNA-binding domain;; Myb-like DNA-binding domain	Telomeric repeat-binding factor 2 GN=TERF2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: telomeric repeat-binding factor 2 isoform X1 [Lipotes vexillifer]
ENSG00000132612(VPS4A)	--	37.52944701	3096	39.184799	3168	39.72341214	3185	34.27333	2849	36.30127	2921	33.458554	2721	0.984461707	-0.150704116	normal	0.985524777	-0.138467673	normal	0.970025677	-0.235326835	normal	0.357070764	-0.175500709	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: DNA helicase activity (GO:0003678);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	"K12196|0|hsa:27183|VPS4A, SKD1, SKD1A, SKD2, VPS4, VPS4-1; vacuolar protein sorting 4 homolog A (S. cerevisiae) (EC:3.6.4.6); K12196 vacuolar protein-sorting-associated protein 4 (A)"	Endocytosis (ko04144)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; Vps4 C terminal oligomerisation domain;; MIT (microtubule interacting and transport) domain;; AAA domain;; IstB-like ATP binding protein;; TIP49 C-terminus;; AAA domain (dynein-related subfamily);; Holliday junction DNA helicase ruvB N-terminus	Vacuolar protein sorting-associated protein 4A OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: vacuolar protein sorting-associated protein 4A [Orcinus orca] 
ENSG00000132613(MTSS1L)	--	18.47116913	1932	18.15027953	1900	19.05461992	2054	21.85529471	2118	21.27844614	2005	17.78143974	1873	0.984054957	0.101697975	normal	0.985459378	0.056132766	normal	0.980397363	-0.141267761	normal	0.987369772	0.005285342	normal	--	--	Biological Process: plasma membrane organization (GO:0007009);; 	--	--	--	--	IRSp53/MIM homology domain	MTSS1-like protein GN=MTSS1L OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: MTSS1-like protein [Ceratotherium simum simum]
ENSG00000132622(HSPA12B)	--	1.844549127	110	2.051005613	125	1.38623901	91	1.525749297	85	1.850456296	108	1.426225096	81	0.909879873	-0.396481512	normal	0.951159327	-0.229335315	normal	0.966020249	-0.173183708	normal	0.577973863	-0.272343548	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Heat shock 70 kDa protein 12B GN=HSPA12B OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 12B isoform X1 [Pteropus alecto]
ENSG00000132623(ANKEF1)	--	9.423321215	793	9.35628388	792	8.905331277	752	8.939501763	764	9.575677474	807	9.311025508	781	0.97358737	-0.084413845	normal	0.97640491	0.005631034	normal	0.975659203	0.046207259	normal	0.97630573	-0.011958858	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat and EF-hand domain-containing protein 1 GN=ANKEF1 OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: ankyrin repeat and EF-hand domain-containing protein 1 [Tupaia chinensis]
ENSG00000132635(PCED1A)	--	25.85051109	861	23.401752	791	22.47308133	752	18.837913	596	22.0611453	730	25.8071021	829	0.15186584	-0.560323846	normal	0.967005722	-0.136935172	normal	0.968812374	0.132094902	normal	0.451145253	-0.178077644	normal	--	--	--	--	--	--	--	GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p	PC-esterase domain-containing protein 1A GN=PCED1A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: PC-esterase domain-containing protein 1A isoform X1 [Galeopterus variegatus]
ENSG00000132639(SNAP25)	--	18.93604945	1082	10.1733344	633	15.99575518	966	8.82518172	570	13.92714627	973	13.123738	883	5.85E-06	-0.953599198	normal	0.085834164	0.597647873	normal	0.970239542	-0.137675673	normal	0.789716958	-0.163719717	normal	--	--	--	"K18211|5.55104e-147|umr:103674434|SNAP25; synaptosomal-associated protein, 25kDa; K18211 synaptosomal-associated protein 25 (A)"	Synaptic vesicle cycle (ko04721);; Insulin secretion (ko04911)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain;; SNAP-25 family	Synaptosomal-associated protein 25 GN=SNAP25 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptosomal-associated protein 25 isoform X1 [Mustela putorius furo]
ENSG00000132640(BTBD3)	--	15.5931602	1118	14.86100487	1076	15.437922	1094	11.28172408	806	11.07569094	792	10.439789	747	0.324628012	-0.502083976	normal	0.509918143	-0.462770956	normal	0.14583151	-0.557785104	normal	0.001110554	-0.509024579	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10478|0|myd:102756452|BTB/POZ domain-containing protein 3-like; K10478 BTB/POZ domain-containing protein 3/6 (A)	--	[S]	Function unknown	PHR domain;; BTB/POZ domain;; BTB And C-terminal Kelch	BTB/POZ domain-containing protein 3 GN=BTBD3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 3-like isoform X1 [Myotis lucifugus]
ENSG00000132646(PCNA)	--	278.5442	6044	295.38437	6447	302.51194	6595	273.16652	6032	258.56403	5611	286.62824	6278	0.994226211	-0.033690922	normal	0.984208478	-0.22174082	normal	0.993856424	-0.079340423	normal	0.624077398	-0.11188268	normal	[L]	"Replication, recombination and repair"	Biological Process: DNA damage checkpoint (GO:0000077);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of DNA replication (GO:0006275);; Cellular Component: checkpoint clamp complex (GO:0030896);; 	K04802|0|ptr:458081|PCNA; proliferating cell nuclear antigen; K04802 proliferating cell nuclear antigen (A)	DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Cell cycle (ko04110);; Hepatitis B (ko05161);; HTLV-I infection (ko05166)	[L]	"Replication, recombination and repair"	"Proliferating cell nuclear antigen, C-terminal domain;; Proliferating cell nuclear antigen, N-terminal domain;; Repair protein Rad1/Rec1/Rad17;; Rad9"	Proliferating cell nuclear antigen GN=PCNA OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	proliferating cell nuclear antigen [Sus scrofa] 
ENSG00000132661(NXT1)	--	34.2151	642	31.0458	596	30.4104	586	34.6501	655	32.5706	608	28.7667	543	0.974521033	-0.001906138	normal	0.97305971	0.007314061	normal	0.966421705	-0.117923677	normal	0.913836245	-0.036134796	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	K14285|7.48571e-101|ptr:458138|NXT1; nuclear transport factor 2-like export factor 1; K14285 NTF2-related export protein 1/2 (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Influenza A (ko05164)	[A]	RNA processing and modification	Nuclear transport factor 2 (NTF2) domain	NTF2-related export protein 1 GN=NXT1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: NTF2-related export protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000132664(POLR3F)	--	7.77305	312	8.10103	326	8.02187	318	8.49956	344	7.87222	315	7.91528	318	0.962682414	0.109516549	normal	0.965023202	-0.070613429	normal	0.968162771	-0.008252198	normal	0.985893701	0.00988012	normal	[K]	Transcription	Cellular Component: DNA-directed RNA polymerase III complex (GO:0005666);; Biological Process: transcription from RNA polymerase III promoter (GO:0006383);; 	"K03025|0|ptr:458117|POLR3F; polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa; K03025 DNA-directed RNA polymerase III subunit RPC6 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpc34 subunit	DNA-directed RNA polymerase III subunit RPC6 GN=POLR3F OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC6 isoform X2 [Ailuropoda melanoleuca] 
ENSG00000132669(RIN2)	--	12.68976503	1052	17.72499291	1451	12.84705978	1059	17.95463722	1425	18.88942429	1489	19.69706573	1600	0.707585175	0.406483193	normal	0.983365889	0.015853366	normal	0.07896701	0.586391914	normal	0.139291545	0.320521258	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar sorting protein 9 (VPS9) domain;; Ras association (RalGDS/AF-6) domain	Ras and Rab interactor 2 GN=RIN2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras and Rab interactor 2 [Ceratotherium simum simum]
ENSG00000132670(PTPRA)	--	45.53649531	2875	43.77777768	2660	40.33198267	2608	46.32308585	2960	47.97272436	3054	47.79292401	3081	0.990004258	0.011197059	normal	0.980700011	0.177752887	normal	0.970176423	0.232039445	normal	0.499780458	0.138367579	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18032|0|hsa:5786|PTPRA, HEPTP, HLPR, HPTPA, HPTPalpha, LRP, PTPA, PTPRL2, R-PTP-alpha, RPTPA; protein tyrosine phosphatase, receptor type, A (EC:3.1.3.48); K18032 receptor-type tyrosine-protein phosphatase A [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain;; Tyrosine phosphatase family;; Inositol hexakisphosphate"	Receptor-type tyrosine-protein phosphatase alpha (Precursor) GN=PTPRA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase alpha isoform X1 [Galeopterus variegatus]
ENSG00000132671(SSTR4)	--	0	0	0.283419	5	0	0	0.115793	2	0.0573368	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04220|0|hsa:6754|SSTR4, SS-4-R, SS4-R, SS4R; somatostatin receptor 4; K04220 somatostatin receptor 4 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srx;; Serpentine type 7TM GPCR chemoreceptor Srw	Somatostatin receptor type 4 GN=SSTR4 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: somatostatin receptor type 4 [Dasypus novemcinctus]
ENSG00000132676(DAP3)	--	54.953686	1645	53.585772	1533	48.488955	1413	64.53931	1904	56.236823	1707	55.167365	1617	0.973355358	0.179957303	normal	0.978345871	0.133553908	normal	0.969538054	0.186080473	normal	0.391959827	0.165557107	normal	--	--	--	"K17408|0|hsa:7818|DAP3, DAP-3, MRP-S29, MRPS29, bMRP-10; death associated protein 3; K17408 small subunit ribosomal protein S29 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal death-associated protein 3	"28S ribosomal protein S29, mitochondrial (Precursor) GN=DAP3 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S29, mitochondrial isoform X2 [Galeopterus variegatus]"
ENSG00000132677(RHBG)	--	0.0361233	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; 	"K06580|0|pps:100977141|RHBG; Rh family, B glycoprotein; K06580 ammonium transporter Rh (A)"	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Ammonium Transporter Family	Ammonium transporter Rh type B GN=RHBG OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: ammonium transporter Rh type B [Galeopterus variegatus]
ENSG00000132680(KIAA0907)	--	17.79523065	1233	19.09984518	1296	18.9410285	1292	16.00940883	1050	16.43571332	1118	16.664827	1121	0.934697263	-0.26226112	normal	0.950443879	-0.234277437	normal	0.958166909	-0.212843531	normal	0.186987015	-0.237244942	normal	--	--	--	--	--	[A]	RNA processing and modification	--	UPF0469 protein KIAA0907 GN=KIAA0907 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: UPF0469 protein KIAA0907 homolog [Bison bison bison]
ENSG00000132688(NES)	--	0.833369783	123	0.46763303	71	0.643420622	96	0.551696189	81	0.937960088	132	0.326160096	48	0.612914335	-0.623819708	normal	0.107929066	0.859593337	normal	0.097920274	-0.98589793	normal	0.862801476	-0.173866322	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	K07609|0|hsa:10763|NES; nestin; K07609 nestin (A)	--	--	--	Intermediate filament protein	Nestin GN=NES OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: nestin [Ceratotherium simum simum]
ENSG00000132692(BCAN)	--	4.49661063	36	4.708860636	39	4.483085401	61	3.471098371	31	2.072021616	31	3.123729876	37	0.980478218	-0.23570852	normal	0.973080578	-0.337902825	normal	0.818870802	-0.706849326	normal	0.460042914	-0.477866473	normal	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	"K06795|0|hsa:63827|BCAN, BEHAB, CSPG7; brevican; K06795 brevican (A)"	--	--	--	Extracellular link domain;; Lectin C-type domain;; Immunoglobulin V-set domain;; Sushi domain (SCR repeat);; EGF-like domain	Brevican core protein (Precursor) GN=BCAN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: brevican core protein [Equus caballus]
ENSG00000132694(ARHGEF11)	--	9.213699302	1427	12.50481965	1675	11.28334655	1658	13.50008053	1417	10.32707234	1490	13.09810177	1727	0.982952826	-0.040933612	normal	0.969264157	-0.190093225	normal	0.984558425	0.050487511	normal	0.813796455	-0.05921354	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K12331|0|ggo:101128400|ARHGEF11; rho guanine nucleotide exchange factor 11 isoform 1; K12331 Rho guanine nucleotide exchange factor 11 (A)	Vascular smooth muscle contraction (ko04270);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	Regulator of G protein signalling-like domain;; RhoGEF domain;; PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Regulator of G protein signaling domain	Rho guanine nucleotide exchange factor 11 GN=ARHGEF11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 11 isoform X3 [Galeopterus variegatus]
ENSG00000132698(RAB25)	--	0.163892	3	0.107515	2	0.263732	4	0.0537485	1	0.106377	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07906|1.43927e-155|ptr:457382|RAB25; RAB25, member RAS oncogene family; K07906 Ras-related protein Rab-25 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-25 (Precursor) GN=RAB25 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-25 [Equus caballus] 
ENSG00000132702(HAPLN2)	--	0.03458605	1	0.203679388	6	0.032863207	0	0.071358875	2	0.03343257	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	"K06851|0|hsa:60484|HAPLN2, BRAL1; hyaluronan and proteoglycan link protein 2; K06851 hyaluronan and proteoglycan link protein 2 (A)"	--	--	--	Extracellular link domain;; Immunoglobulin V-set domain	Hyaluronan and proteoglycan link protein 2 (Precursor) GN=HAPLN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: hyaluronan and proteoglycan link protein 2 isoform X1 [Tupaia chinensis] 
ENSG00000132703(APCS)	--	0	0	0	0	0	0	0	0	0	0	0.0819739	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Pentaxin family	Serum amyloid P-component(1-203) (Precursor) GN=APCS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: serum amyloid P-component-like [Galeopterus variegatus]
ENSG00000132716(DCAF8)	--	43.70644257	2490	38.05707591	2276	43.14573498	2448	41.83636371	2450	46.58672387	2764	43.4185948	2396	0.988042793	-0.054162563	normal	0.958860848	0.258674328	normal	0.988201462	-0.039242587	normal	0.82617788	0.055981376	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11804|0|ptr:457434|DCAF8, WDR42A; DDB1 and CUL4 associated factor 8; K11804 WD repeat-containing protein 42A (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 8 GN=DCAF8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 8 isoform X1 [Oryctolagus cuniculus]
ENSG00000132718(SYT11)	--	2.43172	240	2.29404	226	2.12042	207	0.255133	25	0.358197	35	0.729937	72	0	-3.216034091	down	0	-2.660402107	down	8.32E-08	-1.512251161	down	9.09E-17	-2.368339642	down	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-11 GN=SYT11 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-11 isoform X1 [Galeopterus variegatus]
ENSG00000132740(IGHMBP2)	--	4.126083	346	4.1169755	359	6.013509	438	4.614032274	399	4.319046702	384	4.60019864	412	0.952718047	0.174064249	normal	0.965694617	0.075388818	normal	0.965963442	-0.096235315	normal	0.909622586	0.043467999	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[L]	"Replication, recombination and repair"	"AAA domain;; AAA domain;; Part of AAA domain;; R3H domain;; AAA domain;; Viral (Superfamily 1) RNA helicase;; AN1-like Zinc finger;; Type III restriction enzyme, res subunit;; Helicase;; DEAD/DEAH box helicase"	DNA-binding protein SMUBP-2 GN=IGHMBP2 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA-binding protein SMUBP-2 isoform X3 [Canis lupus familiaris]
ENSG00000132744(ACY3)	--	0.139105222	3	0.4826031	10	0.3183974	6	0.736076637	16	1.4250867	26	1.183322508	26	--	--	--	0.812799994	1.237471564	normal	0.258496703	1.865522991	normal	--	--	--	[E]	Amino acid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	"K18458|0|hsa:91703|ACY3, ACY-3, HCBP1; aspartoacylase (aminocyclase) 3 (EC:3.5.1.114); K18458 N-acyl-aromatic-L-amino acid amidohydrolase [EC:3.5.1.114] (A)"	--	--	--	Succinylglutamate desuccinylase / Aspartoacylase family	N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) GN=ACY3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) [Orycteropus afer afer]
ENSG00000132749(TESMIN)	--	5.299360929	182	5.103983456	190	6.1383486	183	7.020479171	217	4.876170565	200	4.592723259	149	0.943670651	0.221212456	normal	0.96482718	0.052169289	normal	0.919706329	-0.302051432	normal	0.996314771	0.00603479	normal	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	"Tesmin/TSO1-like CXC domain, cysteine-rich domain"	Tesmin GN=MTL5 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: tesmin [Leptonychotes weddellii]
ENSG00000132763(MMACHC)	--	1.959722	141	1.04147	102	2.06159	129	1.938157	147	2.256901	126	1.866579	147	0.967887644	0.028979463	normal	0.940923912	0.279691253	normal	0.957633313	0.17819547	normal	0.755117939	0.154001747	normal	--	--	--	"K14618|0|hsa:25974|MMACHC, cblC; methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria; K14618 methylmalonic aciduria homocystinuria type C protein (A)"	Vitamin digestion and absorption (ko04977)	--	--	--	Methylmalonic aciduria and homocystinuria type C protein GN=MMACHC OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: methylmalonic aciduria and homocystinuria type C protein [Galeopterus variegatus]
ENSG00000132768(DPH2)	--	10.77243188	462	11.78323613	516	12.74503068	554	12.14819861	524	12.70748631	547	11.775359	507	0.95978603	0.150371934	normal	0.969941868	0.062565107	normal	0.963209736	-0.135804015	normal	0.958460685	0.021633	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K17866|0|pps:100981385|DPH2; DPH2 homolog (S. cerevisiae); K17866 diphthamide biosynthesis protein 2 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Putative diphthamide synthesis protein	Diphthamide biosynthesis protein 2 GN=DPH2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: diphthamide biosynthesis protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000132773(TOE1)	--	4.683226	177	4.60532387	177	3.777111296	148	5.19383044	210	6.55551461	243	3.3921521	132	0.945967469	0.214099968	normal	0.769028719	0.432614039	normal	0.958315655	-0.171494082	normal	0.694316789	0.198215755	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K13202|0|hsa:114034|TOE1; target of EGR1, member 1 (nuclear); K13202 target of EGR1 protein 1 (A)"	--	[L]	"Replication, recombination and repair"	CAF1 family ribonuclease;; Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Target of EGR1 protein 1 GN=TOE1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: target of EGR1 protein 1 [Felis catus]
ENSG00000132780(NASP)	--	58.77786246	2385	58.7337486	2397	63.80536237	2420	59.55200446	2601	67.24147959	2708	46.67096067	2002	0.986618008	0.094186759	normal	0.982024988	0.154479535	normal	0.943009116	-0.281662689	normal	1	-0.000161014	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K11291|0|nle:100582677|NASP; nuclear autoantigenic sperm protein (histone-binding); K11291 nuclear autoantigenic sperm protein (A)	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	SHNi-TPR;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Nuclear autoantigenic sperm protein GN=NASP OS=Homo sapiens (Human) PE=1 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nuclear autoantigenic sperm protein isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000132781(MUTYH)	--	4.476175002	150	4.317223	138	5.495208701	190	5.271921344	151	3.4290937	115	4.031949165	120	0.967760001	-0.02103151	normal	0.936617368	-0.281081456	normal	0.272976088	-0.664541856	normal	0.385959786	-0.329877471	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Biological Process: base-excision repair (GO:0006284);; 	K03575|0|ptr:456539|MUTYH; mutY homolog; K03575 A/G-specific adenine glycosylase [EC:3.2.2.-] (A)	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	NUDIX domain;; HhH-GPD superfamily base excision DNA repair protein	A/G-specific adenine DNA glycosylase GN=MUTYH OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: A/G-specific adenine DNA glycosylase isoform X1 [Galeopterus variegatus]
ENSG00000132792(CTNNBL1)	--	22.71904506	928	22.26231314	944	23.27717043	967	24.14824799	1002	26.26484901	1055	19.75961128	808	0.976616032	0.079726491	normal	0.970734951	0.138747346	normal	0.92575291	-0.266994597	normal	0.985016047	-0.008519836	normal	--	--	--	"K12864|0|ptr:458233|CTNNBL1, PDGFRA; catenin, beta like 1; K12864 beta-catenin-like protein 1 (A)"	Spliceosome (ko03040)	[S]	Function unknown	"Catenin-beta-like, Arm-motif containing nuclear;; Armadillo/beta-catenin-like repeat"	Beta-catenin-like protein 1 GN=CTNNBL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: beta-catenin-like protein 1 isoform X2 [Mustela putorius furo] 
ENSG00000132793(LPIN3)	--	5.442100996	551	5.290163324	549	5.168822617	531	5.360816691	484	4.900385795	480	4.73536742	480	0.942185227	-0.217230638	normal	0.942789291	-0.214565632	normal	0.959634326	-0.153508849	normal	0.413513214	-0.196959839	normal	[R]	General function prediction only	--	"K15728|0|hsa:64900|LPIN3, LIPN3L, SMP2; lipin 3 (EC:3.1.3.4); K15728 phosphatidate phosphatase LPIN [EC:3.1.3.4] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[NI]	Cell motility;; Lipid transport and metabolism	"LNS2 (Lipin/Ned1/Smp2);; lipin, N-terminal conserved region"	Phosphatidate phosphatase LPIN3 GN=LPIN3 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: phosphatidate phosphatase LPIN3 [Galeopterus variegatus]
ENSG00000132801(ZSWIM3)	--	1.15373	62	1.23779	67	0.966574	52	0.873472	47	1.12123	60	1.16234	63	0.947556284	-0.418487194	normal	0.969875431	-0.176414828	normal	0.967244078	0.26162667	normal	0.891024712	-0.11112127	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K17604|0|hsa:140831|ZSWIM3, C20orf164, PPP1R174; zinc finger, SWIM-type containing 3; K17604 zinc finger SWIM domain-containing protein 3 (A)"	--	--	--	SWIM zinc finger;; MULE transposase domain;; Transposase	Zinc finger SWIM domain-containing protein 3 GN=ZSWIM3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger SWIM domain-containing protein 3 [Galeopterus variegatus]
ENSG00000132819(RBM38)	--	18.16914	664	16.61978081	625	17.95702	668	16.70468888	620	14.17506097	524	14.010777	495	0.966299087	-0.129437243	normal	0.91307138	-0.274988175	normal	0.603227715	-0.439550562	normal	0.177212351	-0.277665251	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 38 GN=RBM38 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	RNA-binding protein 38 [Sus scrofa] 
ENSG00000132821(VSTM2L)	--	2.491962139	89	2.389223074	87	2.537529	91	4.084129341	129	6.707431	203	5.527604	158	0.811982175	0.497492733	normal	9.14E-05	1.187073559	up	0.139495461	0.777766284	normal	0.006690323	0.855546116	normal	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	V-set and transmembrane domain-containing protein 2-like protein (Precursor) GN=VSTM2L OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: V-set and transmembrane domain-containing protein 2-like protein [Myotis lucifugus] 
ENSG00000132823(OSER1)	--	15.70250833	425	17.35720903	467	16.78230995	452	17.979584	491	18.27870699	493	20.91120591	571	0.953447049	0.176832804	normal	0.969187341	0.056560268	normal	0.861783101	0.32789835	normal	0.450305234	0.189636204	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF776)	Oxidative stress-responsive serine-rich protein 1 GN=OSER1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	hypothetical protein CB1_002228008 [Camelus ferus]
ENSG00000132824(SERINC3)	--	57.95371632	3003	55.89171351	2964	50.79838805	2700	65.87080725	3577	60.13870807	3068	78.27880652	4061	0.975454975	0.221409487	normal	0.989824093	0.028312279	normal	0.103082521	0.580317354	normal	0.136761042	0.283767242	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Serine incorporator (Serinc)	Serine incorporator 3 GN=SERINC3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: serine incorporator 3 [Tupaia chinensis] 
ENSG00000132825(PPP1R3D)	--	2.49425	134	2.26575	123	2.65717	144	2.59919	141	2.94483	158	3.16096	171	0.967902118	0.042158658	normal	0.909981479	0.336184563	normal	0.943981268	0.237346125	normal	0.631895398	0.208690098	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: starch binding (GO:2001070);; 	"K07189|8.89029e-171|hsa:5509|PPP1R3D, PPP1R6; protein phosphatase 1, regulatory subunit 3D (EC:3.1.3.16); K07189 protein phosphatase 1 regulatory subunit 3A/B/C/D/E (A)"	Insulin signaling pathway (ko04910)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Putative phosphatase regulatory subunit	Protein phosphatase 1 regulatory subunit 3D GN=PPP1R3D OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 3D [Galeopterus variegatus]
ENSG00000132842(AP3B1)	--	23.91339973	1753	24.72751832	1918	27.1120237	1947	28.3906466	2247	29.11039731	2193	27.12919286	2057	0.899960152	0.327088116	normal	0.976857566	0.171749818	normal	0.985537635	0.070943852	normal	0.310672382	0.188361906	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; 	"K12397|0|ptr:461789|AP3B1; adaptor-related protein complex 3, beta 1 subunit; K12397 AP-3 complex subunit beta (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Adaptin N terminal region;; Clathrin-adaptor complex-3 beta-1 subunit C-terminal;; Serine-rich region of AP3B1, clathrin-adaptor complex;; HEAT repeats;; non-SMC mitotic condensation complex subunit 1;; HEAT repeat;; HEAT-like repeat"	AP-3 complex subunit beta-1 GN=AP3B1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-3 complex subunit beta-1-like [Odobenus rosmarus divergens]
ENSG00000132846(ZBED3)	--	3.672600901	277	4.038068533	295	2.41960593	213	4.762495017	326	4.379523996	422	5.7009194	529	0.94494957	0.203114396	normal	0.500980488	0.492978269	normal	2.78E-09	1.298075476	up	0.060236878	0.681745801	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	BED zinc finger	Zinc finger BED domain-containing protein 3 GN=ZBED3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger BED domain-containing protein 3 [Bos taurus] 
ENSG00000132849(PATJ)	--	6.667293201	672	5.02993482	724	5.401137412	712	4.299078658	650	7.290276575	588	6.491910045	721	0.972010582	-0.078670872	normal	0.872468774	-0.320854907	normal	0.9757174	0.009809871	normal	0.60784187	-0.126664025	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06092|0|hsa:10207|INADL, Cipp, PATJ, hINADL; InaD-like (Drosophila); K06092 InaD-like protein (A)"	Hippo signaling pathway (ko04390);; Tight junction (ko04530)	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; L27_2;; Tricorn protease PDZ domain	InaD-like protein GN=INADL OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: inaD-like protein isoformX3 [Canis lupus familiaris]
ENSG00000132854(KANK4)	--	0	0	0.025271917	2	0	0	0.1887559	11	0.260532051	23	0.119423672	11	--	--	--	0.023127558	2.78687571	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	KN motif;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	KN motif and ankyrin repeat domain-containing protein 4 GN=KANK4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: KN motif and ankyrin repeat domain-containing protein 4 [Felis catus] 
ENSG00000132855(ANGPTL3)	--	0	0	0.111424	5	0.0668108	2	0.0214443	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-related protein 3 (Precursor) GN=ANGPTL3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: angiopoietin-related protein 3 [Galeopterus variegatus]
ENSG00000132879(FBXO44)	--	20.46289921	680	16.86715791	585	18.44594598	626	10.65090753	371	12.95140993	374	13.401829	412	9.25E-05	-0.902143107	normal	0.038478966	-0.664657004	normal	0.085651732	-0.609979798	normal	3.07E-05	-0.729629673	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10103|2.83789e-127|pps:100978399|FBXO44; F-box protein 44; K10103 F-box protein 44 (A)	--	--	--	F-box associated region;; F-box-like;; F-box domain;; F-box associated region	F-box only protein 44 GN=FBXO44 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: F-box only protein 44 isoform X1 [Tupaia chinensis]
ENSG00000132881(RSG1)	--	2.147339578	177	1.937101879	176	1.980160229	203	2.448559	179	1.963897493	127	2.595337381	197	0.967157396	-0.014496905	normal	0.740536872	-0.487221801	normal	0.966037423	-0.051188419	normal	0.690662532	-0.165307058	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[R]	General function prediction only	Miro-like protein;; Ras family	REM2- and Rab-like small GTPase 1 GN=RSG1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: REM2- and Rab-like small GTPase 1 isoform X1 [Equus caballus] 
ENSG00000132906(CASP9)	--	7.245301035	273	5.89344129	253	7.723863024	304	4.178412153	185	4.86059954	201	4.782445519	198	0.312045	-0.588159082	normal	0.867618752	-0.35100876	normal	0.188436715	-0.622992298	normal	0.038781906	-0.527818808	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K04399|0|hsa:842|CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56; caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62); K04399 caspase 9 [EC:3.4.22.62] (A)"	p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; VEGF signaling pathway (ko04370);; Thyroid hormone signaling pathway (ko04919);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Viral myocarditis (ko05416)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain;; Caspase recruitment domain	Caspase-9 subunit p10 (Precursor) GN=CASP9 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-9 [Ceratotherium simum simum]
ENSG00000132911(NMUR2)	--	0.0645626	2	0	0	0	0	0.290066	9	0.376098	11	0.15928	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05053|0|hsa:56923|NMUR2, FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1; neuromedin U receptor 2; K05053 neuromedin U receptor 2 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srw	Neuromedin-U receptor 2 GN=NMUR2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: neuromedin-U receptor 2 [Camelus dromedarius]
ENSG00000132912(DCTN4)	--	13.22123145	1059	14.28205848	1121	13.11253695	996	14.89015352	1186	14.39534555	1210	16.086053	1271	0.973644852	0.132387601	normal	0.977975835	0.088679047	normal	0.852338515	0.342992839	normal	0.340499156	0.186238533	normal	--	--	Cellular Component: dynactin complex (GO:0005869);; 	"K10426|0|hsa:51164|DCTN4, DYN4, P62; dynactin 4 (p62); K10426 dynactin 4 (A)"	Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016)	[N]	Cell motility	Dynactin p62 family	Dynactin subunit 4 GN=DCTN4 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: dynactin subunit 4 isoform X1 [Mustela putorius furo] 
ENSG00000132915(PDE6A)	--	0.19370672	15	0.09874685	10	0.105343634	8	0.095891629	8	0.175270021	14	0.161966407	14	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; "	"K08718|0|hsa:5145|PDE6A, CGPR-A, PDEA, RP43; phosphodiesterase 6A, cGMP-specific, rod, alpha (EC:3.1.4.35); K08718 rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha [EC:3.1.4.35] (A)"	Purine metabolism (ko00230);; Phototransduction (ko04744)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; GAF domain;; GAF domain;; GAF domain	"Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha (Precursor) GN=PDE6A OS=Homo sapiens (Human) PE=1 SV=4"	T	Signal transduction mechanisms	"PREDICTED: rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha isoform X1 [Orycteropus afer afer]"
ENSG00000132932(ATP8A2)	--	0	0	0	0	0	0	0	0	0.00528321	0	0.033184516	2	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	"K14802|0|hsa:51761|ATP8A2, ATP, ATPIB, CAMRQ4, IB, ML-1; ATPase, aminophospholipid transporter, class I, type 8A, member 2 (EC:3.6.3.1); K14802 phospholipid-transporting ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase	Phospholipid-transporting ATPase IB GN=ATP8A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IB isoformX1 [Canis lupus familiaris]
ENSG00000132938(MTUS2)	--	0	0	0	0	0	0	0	0	0.024727604	1	0.025833901	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Microtubule-associated tumor suppressor candidate 2 GN=MTUS2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: microtubule-associated tumor suppressor candidate 2 isoform 1 [Ceratotherium simum simum]
ENSG00000132950(ZMYM5)	--	4.379441765	175	4.402306001	186	3.603208383	155	3.691633547	162	4.070475	186	4.243922522	191	0.960099547	-0.140907106	normal	0.965735675	-0.021253755	normal	0.923271744	0.290455787	normal	0.943862623	0.041970337	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	MYM-type Zinc finger with FCS sequence motif	Zinc finger MYM-type protein 5 GN=ZMYM5 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: zinc finger MYM-type protein 5 isoform X1 [Galeopterus variegatus]
ENSG00000132952(USPL1)	--	6.367538162	477	7.685966	563	6.587859499	481	6.002115997	447	7.067536327	537	6.070566495	474	0.963355624	-0.124133544	normal	0.968400017	-0.089393493	normal	0.971009001	-0.029348324	normal	0.789634621	-0.082139185	normal	--	--	Molecular Function: SUMO binding (GO:0032183);; Molecular Function: SUMO-specific isopeptidase activity (GO:0070140);; 	--	--	--	--	"Domain of unknown function (DUF4650);; Ubiquitin-specific peptidase-like, SUMO isopeptidase"	SUMO-specific isopeptidase USPL1 GN=USPL1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: SUMO-specific isopeptidase USPL1 [Ceratotherium simum simum]
ENSG00000132953(XPO4)	--	5.82923197	854	6.743671717	932	6.587199342	924	6.882740901	1005	6.479080212	935	5.851533069	852	0.955782417	0.203717137	normal	0.978164919	-0.016762992	normal	0.971359418	-0.125117543	normal	0.949678474	0.02136588	normal	--	--	--	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	CRM1 C terminal	Exportin-4 GN=XPO4 OS=Homo sapiens (Human) PE=1 SV=2	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: exportin-4 isoform X6 [Canis lupus familiaris] 
ENSG00000132963(POMP)	--	66.47491	1054	76.307112	1215	78.42828	1228	84.508438	1375	74.882393	1187	76.126491	1213	0.838814344	0.352273787	normal	0.980165835	-0.054993682	normal	0.981640445	-0.025990248	normal	0.707950128	0.088853082	normal	--	--	--	K11599|5.50351e-86|pps:100976592|POMP; proteasome maturation protein; K11599 proteasome maturation protein (A)	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome maturation factor UMP1	Proteasome maturation protein OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	proteasome maturation protein [Bos taurus] 
ENSG00000132964(CDK8)	--	7.779536351	414	7.452987274	396	8.128440417	429	8.181066776	435	7.168893908	382	8.043640525	431	0.969463383	0.040406079	normal	0.966230705	-0.073070211	normal	0.970413968	-0.001575679	normal	0.984925516	-0.010720072	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02208|0|pps:100984451|CDK8; cyclin-dependent kinase 8; K02208 cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23] (A)	--	[K]	Transcription	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 8 GN=CDK8 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cyclin-dependent kinase 8 isoform X1 [Capra hircus] 
ENSG00000132965(ALOX5AP)	--	1.249871032	14	0.97904521	11	0.613745401	6	4.062261353	46	5.17888176	58	3.23938147	37	0.049152971	1.584566647	normal	4.50E-05	2.229982825	up	0.002367728	2.350700615	up	5.15E-05	2.162695642	up	--	--	--	--	--	--	--	MAPEG family	Arachidonate 5-lipoxygenase-activating protein GN=ALOX5AP OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: arachidonate 5-lipoxygenase-activating protein [Canis lupus familiaris]
ENSG00000132970(WASF3)	--	0.686812423	55	0.55569141	45	0.440305	34	0.242978234	20	0.397430772	31	0.17518756	14	0.042306797	-1.421713482	normal	0.944410593	-0.53720676	normal	0.659828706	-1.202617568	normal	0.052413331	-1.06602454	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	"K06083|0|pps:100983777|WASF3; WAS protein family, member 3; K06083 WAS protein family, member 3 (A)"	Adherens junction (ko04520);; Fc gamma R-mediated phagocytosis (ko04666);; Choline metabolism in cancer (ko05231)	[Z]	Cytoskeleton	WH2 motif	Wiskott-Aldrich syndrome protein family member 3 GN=WASF3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: wiskott-Aldrich syndrome protein family member 3 isoform X2 [Ailuropoda melanoleuca] 
ENSG00000133019(CHRM3)	--	0.09653	10	0.109551757	17	0.04793309	6	0.08307668	12	1.0095872	28	0.529596898	30	--	--	--	0.962818574	0.652830231	normal	0.05578208	2.061332449	normal	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04131|0|hsa:1131|CHRM3, EGBRS, HM3; cholinergic receptor, muscarinic 3; K04131 muscarinic acetylcholine receptor M3 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725);; Regulation of actin cytoskeleton (ko04810);; Insulin secretion (ko04911);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Muscarinic acetylcholine receptor M3 GN=CHRM3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: muscarinic acetylcholine receptor M3-like [Ceratotherium simum simum]
ENSG00000133026(MYH10)	--	25.671776	4932	23.37010748	4531	26.47119229	5115	22.39535964	4318	23.38090223	4482	17.94686695	3452	0.980642243	-0.222567648	normal	0.992420314	-0.037100949	normal	0.125488051	-0.575384765	normal	0.114929925	-0.272376813	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10352|0|cjc:100408747|MYH10; myosin, heavy chain 10, non-muscle; K10352 myosin heavy chain (A)"	Tight junction (ko04530)	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; Myosin N-terminal SH3-like domain;; IQ calmodulin-binding motif	Myosin-10 GN=MYH10 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: myosin-10 [Elephantulus edwardii]
ENSG00000133027(PEMT)	--	60.32710069	872	50.39160877	739	53.52760828	796	31.11358157	456	38.79274573	560	35.090188	515	7.56E-06	-0.963734559	normal	0.669750453	-0.420581906	normal	0.042112641	-0.634975518	normal	3.74E-05	-0.673506981	normal	--	--	--	K00551|8.24659e-132|pps:100972213|PEMT; phosphatidylethanolamine N-methyltransferase; K00551 phosphatidylethanolamine N-methyltransferase [EC:2.1.1.17] (A)	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Phospholipid methyltransferase	Phosphatidylethanolamine N-methyltransferase GN=PEMT OS=Homo sapiens (Human) PE=1 SV=4	I	Lipid transport and metabolism	PREDICTED: phosphatidylethanolamine N-methyltransferase [Condylura cristata]
ENSG00000133028(SCO1)	--	44.48589393	1927	40.47869406	1812	42.28416087	1801	50.5251097	2357	51.59706365	2511	38.38879554	1909	0.953593721	0.25957554	normal	0.612200804	0.448932955	normal	0.98455797	0.07566576	normal	0.121440242	0.269000134	normal	[R]	General function prediction only	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07152|0|hsa:6341|SCO1, SCOD1; SCO1 cytochrome c oxidase assembly protein; K07152 protein SCO1/2 (A)"	--	[C]	Energy production and conversion	SCO1/SenC;; AhpC/TSA family	"Protein SCO1 homolog, mitochondrial (Precursor) GN=SCO1 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: protein SCO1 homolog, mitochondrial [Galeopterus variegatus]"
ENSG00000133030(MPRIP)	--	85.50656524	9152	78.31994721	9942	84.31683975	9828	86.892024	10337	91.09362473	10323	71.49176497	9468	0.994061514	0.144803445	normal	0.996060485	0.032822832	normal	0.995800702	-0.062119854	normal	0.900147375	0.037544401	normal	--	--	--	--	--	[Z]	Cytoskeleton	--	Myosin phosphatase Rho-interacting protein OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: myosin phosphatase Rho-interacting protein isoform X1 [Galeopterus variegatus]
ENSG00000133048(CHI3L1)	--	0	0	0	0	0	0	0	0	0	0	0.033822993	1	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K17523|0|hsa:1116|CHI3L1, ASRT7, CGP-39, GP-39, GP39, HC-gp39, HCGP-3P, YKL-40, YKL40, YYL-40, hCGP-39; chitinase 3-like 1 (cartilage glycoprotein-39); K17523 chitinase-3-like protein 1/2 (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 18	Chitinase-3-like protein 1 (Precursor) GN=CHI3L1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: chitinase-3-like protein 1 isoform X3 [Tupaia chinensis] 
ENSG00000133055(MYBPH)	--	0	0	0	0	0	0	0	0	0	0	0.02601574	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Myosin-binding protein H GN=MYBPH OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: myosin-binding protein H [Tupaia chinensis]
ENSG00000133056(PIK3C2B)	--	5.039649197	651	6.190764704	657	5.262388865	697	5.592546874	578	5.593725105	682	6.654914956	768	0.949625244	-0.201914176	normal	0.973868756	0.032378661	normal	0.967873102	0.13138455	normal	0.992813832	-0.003750722	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K00923|0|hsa:5287|PIK3C2B, C2-PI3K; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta (EC:2.7.1.154); K00923 phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	"Phosphatidylinositol 3- and 4-kinase;; Phosphoinositide 3-kinase family, accessory domain (PIK domain);; Phosphoinositide 3-kinase C2;; PI3-kinase family, ras-binding domain;; PX domain;; C2 domain"	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta GN=PIK3C2B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta [Galeopterus variegatus]
ENSG00000133059(DSTYK)	--	5.427544	801	5.779455524	869	5.277605117	776	6.942724	1031	6.463293219	937	5.948736423	833	0.860293014	0.332774065	normal	0.974787009	0.087120288	normal	0.97333418	0.093791951	normal	0.406125815	0.173540556	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16288|0|hsa:25778|DSTYK, CAKUT1, DustyPK, RIP5, RIPK5; dual serine/threonine and tyrosine protein kinase (EC:2.7.12.1); K16288 receptor-interacting serine/threonine-protein kinase 5 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Dual serine/threonine and tyrosine protein kinase GN=DSTYK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual serine/threonine and tyrosine protein kinase isoform 1 [Trichechus manatus latirostris]
ENSG00000133065(SLC41A1)	--	11.07714054	1012	12.510067	1121	14.060088	1255	12.499558	1124	12.51930631	1133	11.93312026	1086	0.974368031	0.12042695	normal	0.980470577	-0.006056847	normal	0.956280018	-0.216673765	normal	0.887347976	-0.040288305	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; 	"K15122|0|ptr:469655|SLC41A1; solute carrier family 41 (magnesium transporter), member 1; K15122 solute carrier family 41 (A)"	--	[P]	Inorganic ion transport and metabolism	Divalent cation transporter	Solute carrier family 41 member 1 GN=SLC41A1 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 41 member 1 [Galeopterus variegatus]
ENSG00000133067(LGR6)	--	0.354399731	21	0.145670818	8	0.38047601	20	0.494675979	29	1.064607603	66	0.302152287	17	0.979520956	0.40926613	normal	5.43E-08	2.80780313	up	0.988216208	-0.224339101	normal	0.38695326	1.171821442	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K08399|0|hsa:59352|LGR6, GPCR, VTS20631; leucine-rich repeat containing G protein-coupled receptor 6; K08399 leucine-rich repeat-containing G protein-coupled receptor 6 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine-rich repeat;; 7 transmembrane receptor (rhodopsin family);; Leucine rich repeat N-terminal domain	Leucine-rich repeat-containing G-protein coupled receptor 6 (Precursor) GN=LGR6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing G-protein coupled receptor 6 isoform 1 [Trichechus manatus latirostris]
ENSG00000133069(TMCC2)	--	1.892063301	142	1.649446785	117	2.85126926	225	2.884669012	211	2.11374527	161	1.852485648	137	0.581422814	0.535737242	normal	0.835054281	0.434321991	normal	0.106167356	-0.717793846	normal	0.956074846	0.051194872	normal	--	--	--	--	--	[S]	Function unknown	Predicted transmembrane and coiled-coil 2 protein	Transmembrane and coiled-coil domains protein 2 GN=TMCC2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transmembrane and coiled-coil domains protein 2 isoform X3 [Ailuropoda melanoleuca]
ENSG00000133083(DCLK1)	--	0.605164019	42	0.14166799	9	0.481833866	31	1.239049318	71	0.70845502	39	0.417746284	29	0.767968399	0.70652035	normal	0.017482232	1.926797938	normal	0.984301829	-0.099487853	normal	0.485042379	0.737927322	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	K08805|0|cjc:100401876|DCLK1; doublecortin-like kinase 1; K08805 doublecortin-like kinase 1/2 [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Doublecortin;; Protein tyrosine kinase	Serine/threonine-protein kinase DCLK1 GN=DCLK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase DCLK1 isoform X2 [Ailuropoda melanoleuca]
ENSG00000133101(CCNA1)	--	0.086939373	3	0	0	0	0	0	0	0	0	0.031065528	1	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	K06627|0|pps:100983938|CCNA1; cyclin A1; K06627 cyclin A (A)	Cell cycle (ko04110);; AMPK signaling pathway (ko04152);; Progesterone-mediated oocyte maturation (ko04914);; Hepatitis B (ko05161);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	Cyclin-A1 GN=CCNA1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-A1 isoform X1 [Equus caballus]
ENSG00000133103(COG6)	--	5.764782869	326	4.82400702	282	5.323660528	299	5.411366831	318	5.513104475	313	5.4639002	307	0.966230972	-0.066360776	normal	0.959032721	0.128387217	normal	0.967556868	0.029653711	normal	0.955958996	0.027195047	normal	--	--	--	--	--	[S]	Function unknown	Conserved oligomeric complex COG6	Conserved oligomeric Golgi complex subunit 6 GN=COG6 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: conserved oligomeric Golgi complex subunit 6 [Ceratotherium simum simum]
ENSG00000133104(SPG20)	--	17.59366224	1100	18.68696048	1157	18.58138656	1150	16.82731743	1068	20.76100829	1284	21.70950563	1348	0.978473819	-0.073320198	normal	0.974944257	0.128670084	normal	0.956273514	0.220626955	normal	0.674722709	0.098586275	normal	--	--	--	--	--	[S]	Function unknown	Senescence-associated protein;; MIT (microtubule interacting and transport) domain	Spartin GN=SPG20 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: spartin-like isoform X1 [Tupaia chinensis]
ENSG00000133106(EPSTI1)	--	0	0	0	0	0.037372276	1	0.097382184	2	0.19108044	6	0.048905763	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Epithelial-stromal interaction protein 1 GN=EPSTI1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: epithelial-stromal interaction protein 1 [Ceratotherium simum simum]
ENSG00000133107(TRPC4)	--	0.020676261	1	0.022154338	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04967|0|ptr:452544|TRPC4; transient receptor potential cation channel, subfamily C, member 4; K04967 transient receptor potential cation channel subfamily C member 4 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Transient receptor ion channel II;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Short transient receptor potential channel 4 GN=TRPC4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: short transient receptor potential channel 4 isoform X1 [Oryctolagus cuniculus] 
ENSG00000133110(POSTN)	--	0.0325766	2	0	0	0	0	0	0	0.016938313	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	--	--	--	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Fasciclin domain	Periostin (Precursor) GN=POSTN OS=Homo sapiens (Human) PE=1 SV=2	MW	Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: periostin isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000133111(RFXAP)	--	2.69476	93	1.54613	55	1.76588	62	1.83839	65	1.83869	64	1.93655	68	0.843555125	-0.536951364	normal	0.970188755	0.192308364	normal	0.973420877	0.122129752	normal	0.880880834	-0.113450467	normal	--	--	--	K08063|1.08339e-102|hsa:5994|RFXAP; regulatory factor X-associated protein; K08063 regulatory factor X-associated protein (A)	Antigen processing and presentation (ko04612);; Tuberculosis (ko05152);; Primary immunodeficiency (ko05340)	--	--	Regulatory factor X-associated C-terminal binding domain	Regulatory factor X-associated protein GN=RFXAP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: regulatory factor X-associated protein [Ceratotherium simum simum]
ENSG00000133112(TPT1)	--	921.3557398	17494	906.0819639	16909	899.0218362	16856	914.3653618	17214	926.5899195	17431	1011.329359	19057	0.997506172	-0.054105298	normal	0.997482343	0.022435463	normal	0.995762557	0.168753116	normal	0.883493494	0.046251886	normal	--	--	--	--	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Translationally controlled tumour protein	Translationally-controlled tumor protein GN=TPT1 OS=Homo sapiens (Human) PE=1 SV=1	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: translationally-controlled tumor protein isoform X1 [Vicugna pacos]
ENSG00000133114(GPALPP1)	--	5.735305821	397	7.8332513	392	8.310985501	425	8.088948169	452	8.12437	491	7.584830002	430	0.957409518	0.155786204	normal	0.890504722	0.30239854	normal	0.970331191	0.008552123	normal	0.573132395	0.156423611	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF3752)	GPALPP motifs-containing protein 1 GN=GPALPP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: GPALPP motifs-containing protein 1 isoform X2 [Loxodonta africana]
ENSG00000133116(KL)	--	0.0126956	1	0	0	0.0251561	1	0.0126378	1	0	0	0.0125849	1	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	K14756|0|hsa:9365|KL; klotho (EC:3.2.1.31); K14756 klotho [EC:3.2.1.31] (A)	Pentose and glucuronate interconversions (ko00040);; Starch and sucrose metabolism (ko00500);; Endocrine and other factor-regulated calcium reabsorption (ko04961)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 1	Klotho peptide (Precursor) GN=KL OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: klotho [Leptonychotes weddellii]
ENSG00000133119(RFC3)	--	22.782363	811	26.26434864	931	26.67916	932	25.243166	902	26.01732	925	19.790135	705	0.971074757	0.122373366	normal	0.977843183	-0.030704324	normal	0.686828645	-0.410230212	normal	0.685025699	-0.100454101	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K10756|0|ptg:102967482|RFC3; replication factor C (activator 1) 3, 38kDa; K10756 replication factor C subunit 3/5 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430)	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	"Replication factor C C-terminal domain;; DNA polymerase III, delta subunit;; ATPase family associated with various cellular activities (AAA);; Rad17 cell cycle checkpoint protein;; DNA polymerase III, delta subunit"	Replication factor C subunit 3 GN=RFC3 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: replication factor C subunit 3 [Ceratotherium simum simum]
ENSG00000133121(STARD13)	--	0.902448008	104	1.301909738	135	0.962370608	116	1.752787813	213	1.278201704	156	1.664642651	203	0.001990661	0.992983801	normal	0.954327963	0.18522854	normal	0.05500884	0.791168468	normal	0.027118352	0.66660762	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Molecular Function: lipid binding (GO:0008289);; 	--	--	[T]	Signal transduction mechanisms	START domain;; RhoGAP domain;; SAM domain (Sterile alpha motif)	StAR-related lipid transfer protein 13 GN=STARD13 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: stAR-related lipid transfer protein 13 [Equus caballus]
ENSG00000133131(MORC4)	--	41.85592979	3118	22.68330586	1693	34.82974137	2456	65.10333387	4562	85.52695482	5820	55.07441694	3812	0.329383977	0.518001103	normal	0	1.759109665	up	0.035772142	0.625634471	normal	0.00830858	0.94451301	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	"Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; CW-type Zinc Finger;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	MORC family CW-type zinc finger protein 4 GN=MORC4 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: MORC family CW-type zinc finger protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000133134(BEX2)	--	5.579112161	81	8.401390331	117	5.925973	87	2.143009284	31	1.980623	28	4.034314264	59	0.00481748	-1.372791209	down	1.97E-08	-2.026389879	down	0.843111766	-0.556766621	normal	0.001074023	-1.291706505	down	--	--	--	--	--	--	--	Brain expressed X-linked like family	Protein BEX2 GN=BEX2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"Protein BEX2, partial [Pteropus alecto]"
ENSG00000133135(RNF128)	--	0.139521755	5	0.027744837	1	0.09881034	3	0.074160737	3	0.1936374	7	0.027595753	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10629|0|pps:100975786|RNF128; ring finger protein 128, E3 ubiquitin protein ligase; K10629 E3 ubiquitin-protein ligase RNF128 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; PA domain;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	E3 ubiquitin-protein ligase RNF128 (Precursor) GN=RNF128 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF128 isoform X1 [Felis catus]
ENSG00000133138(TBC1D8B)	--	4.564925	435	4.593972	414	4.4254884	414	3.491603	342	3.846564909	343	3.367734	335	0.796202195	-0.376347974	normal	0.900431221	-0.29167624	normal	0.883270951	-0.312489678	normal	0.159552511	-0.329560542	normal	--	--	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; GRAM domain	TBC1 domain family member 8B GN=TBC1D8B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: TBC1 domain family member 8B [Ceratotherium simum simum]
ENSG00000133142(TCEAL4)	--	45.54135342	1350	49.96747491	1564	50.053515	1528	45.27769782	1399	42.87723955	1269	44.01129998	1333	0.982981458	0.020581282	normal	0.892852953	-0.32262796	normal	0.963896124	-0.205041753	normal	0.375580777	-0.172165274	normal	--	--	--	--	--	--	--	Brain expressed X-linked like family	Transcription elongation factor A protein-like 4 GN=TCEAL4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription elongation factor A protein-like 4 [Trichechus manatus latirostris]
ENSG00000133193(FAM104A)	--	23.25419	1023	21.6941218	980	22.285415	1042	22.0933	1054	21.356204	980	20.567207	871	0.97992944	0.01221838	normal	0.978678675	-0.021393545	normal	0.927846234	-0.266478483	normal	0.717480866	-0.089576896	normal	--	--	--	--	--	--	--	Family 104	Protein FAM104A GN=FAM104A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM104A isoform X1 [Mustela putorius furo] 
ENSG00000133195(SLC39A11)	--	46.34942	1023	35.14425542	829	44.49978	878	27.6555664	593	30.13561416	740	25.89555	573	0.000387459	-0.815903421	normal	0.957992493	-0.184916114	normal	0.049356267	-0.622639384	normal	0.002391309	-0.53956025	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14717|0|hsa:201266|SLC39A11, C17orf26, ZIP11; solute carrier family 39, member 11; K14717 solute carrier family 39 (zinc transporter), member 11 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP11 GN=SLC39A11 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP11 isoform 1 [Ceratotherium simum simum]
ENSG00000133216(EPHB2)	--	35.78205448	3081	31.9286708	2623	31.9527306	2673	79.01828094	7288	84.3503502	7897	62.5564051	5494	1.97E-11	1.210887782	up	0	1.568113256	up	5.80E-08	1.030690185	up	1.40E-07	1.281709312	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05111|0|hsa:2048|EPHB2, CAPB, DRT, EK5, EPHT3, ERK, Hek5, PCBC, Tyro5; EPH receptor B2 (EC:2.7.10.1); K05111 Eph receptor B2 [EC:2.7.10.1] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; GCC2 and GCC3	Ephrin type-B receptor 2 (Precursor) GN=EPHB2 OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: ephrin type-B receptor 2 isoform X1 [Orycteropus afer afer]
ENSG00000133226(SRRM1)	--	16.7697263	1518	17.3989685	1532	18.03150099	1594	16.88174635	1506	17.967651	1629	15.5383796	1412	0.983581693	-0.042239362	normal	0.982825785	0.06707953	normal	0.970049098	-0.183018372	normal	0.843370735	-0.051693347	normal	--	--	Biological Process: mRNA processing (GO:0006397);; 	K13171|2.22766e-70|ssc:100521629|SRRM1; serine/arginine repetitive matrix 1; K13171 serine/arginine repetitive matrix protein 1 (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[AR]	RNA processing and modification;; General function prediction only	PWI domain	Serine/arginine repetitive matrix protein 1 GN=SRRM1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: serine/arginine repetitive matrix protein 1 isoform X6 [Bos taurus] 
ENSG00000133243(BTBD2)	--	41.31717605	1908	35.63165668	1686	34.81581146	1672	35.30288237	1630	42.18949866	1922	39.01034003	1798	0.949212983	-0.257796578	normal	0.975531262	0.167436504	normal	0.982696294	0.096442598	normal	0.999834061	0.001891764	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10477|0|hsa:55643|BTBD2; BTB (POZ) domain containing 2; K10477 BTB/POZ domain-containing protein 1/2 (A)	--	[S]	Function unknown	PHR domain;; BTB/POZ domain;; BTB And C-terminal Kelch	BTB/POZ domain-containing protein 2 GN=BTBD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 2 [Vicugna pacos]
ENSG00000133246(PRAM1)	--	0.070372209	4	0.03682495	2	0.102509316	5	0.054762394	3	0	0	0.035621435	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Helically-extended SH3 domain;; Variant SH3 domain	PML-RARA-regulated adapter molecule 1 GN=PRAM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: PML-RARA-regulated adapter molecule 1 [Galeopterus variegatus]
ENSG00000133247(KMT5C)	--	5.051806626	226	6.270857264	276	6.17714087	283	5.8016049	251	6.352914758	282	5.237664362	236	0.960895089	0.119759566	normal	0.966464112	0.009548579	normal	0.921423534	-0.268731817	normal	0.9074175	-0.050818916	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11429|0|hsa:84787|SUV420H2, KMT5C; suppressor of variegation 4-20 homolog 2 (Drosophila) (EC:2.1.1.43); K11429 histone-lysine N-methyltransferase SUV420H [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[B]	Chromatin structure and dynamics	SET domain	Histone-lysine N-methyltransferase SUV420H2 GN=SUV420H2 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	hypothetical protein PANDA_016084 [Ailuropoda melanoleuca]
ENSG00000133250(ZNF414)	--	10.52128986	173	6.195528361	165	7.028033344	146	9.563167593	128	9.533011768	139	12.25629644	163	0.787304957	-0.460683874	normal	0.934982952	-0.266146301	normal	0.959905468	0.149149378	normal	0.65636697	-0.191376293	normal	--	--	--	--	--	[R]	General function prediction only	--	Zinc finger protein 414 GN=ZNF414 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 414 [Galeopterus variegatus]
ENSG00000133256(PDE6B)	--	0.038278697	2	0	0	0	0	0	0	0.018593258	0	0.018928019	1	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; "	"K13756|0|hsa:5158|PDE6B, CSNB3, CSNBAD2, PDEB, RP40, rd1; phosphodiesterase 6B, cGMP-specific, rod, beta (EC:3.1.4.35); K13756 rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta [EC:3.1.4.35] (A)"	Purine metabolism (ko00230);; Phototransduction (ko04744)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; GAF domain;; GAF domain;; GAF domain	"Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta (Precursor) GN=PDE6B OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta isoform X2 [Mustela putorius furo] "
ENSG00000133265(HSPBP1)	--	55.742236	1477	54.77034328	1592	57.86473239	1647	55.58313344	1518	54.62190795	1462	54.88067807	1506	0.984003814	0.008660815	normal	0.976302781	-0.144180606	normal	0.977923236	-0.137278359	normal	0.683826939	-0.093247106	normal	--	--	--	"K09562|7.69138e-166|hsa:23640|HSPBP1, FES1; HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1; K09562 hsp70-interacting protein (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Armadillo/beta-catenin-like repeat	Hsp70-binding protein 1 GN=HSPBP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: hsp70-binding protein 1 [Loxodonta africana]
ENSG00000133275(CSNK1G2)	--	25.82722719	1396	23.89922265	1348	26.31736009	1454	26.5116733	1436	29.47275531	1594	27.96798065	1497	0.983405341	0.009913786	normal	0.959919387	0.220177208	normal	0.983555591	0.033720944	normal	0.708148899	0.087946205	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08958|0|hsa:1455|CSNK1G2, CK1g2; casein kinase 1, gamma 2 (EC:2.7.11.1); K08958 casein kinase 1, gamma [EC:2.7.11.1] (A)"	Hedgehog signaling pathway (ko04340)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Casein kinase 1 gamma C terminal	Casein kinase I isoform gamma-2 GN=CSNK1G2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: casein kinase I isoform gamma-2 isoform 2 [Ceratotherium simum simum]
ENSG00000133302(SLF1)	--	6.193955025	570	6.418948002	587	6.914476282	619	5.801124	540	5.263206	481	5.113140669	472	0.967218052	-0.108534143	normal	0.885011897	-0.307872306	normal	0.730838961	-0.398326013	normal	0.204100894	-0.271928146	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; BRCA1 C Terminus (BRCT) domain	Ankyrin repeat domain-containing protein 32 GN=ANKRD32 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: ankyrin repeat domain-containing protein 32 [Equus caballus] 
ENSG00000133313(CNDP2)	--	47.77325089	2024	40.64836771	1869	50.08871312	2085	46.62866252	1912	41.1363595	1812	38.80325417	1747	0.982978077	-0.112870855	normal	0.984518458	-0.066055885	normal	0.948853636	-0.263250334	normal	0.456726606	-0.149183449	normal	[E]	Amino acid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	K08660|0|ptr:455473|CNDP2; CNDP dipeptidase 2 (metallopeptidase M20 family) (EC:3.4.13.18); K08660 cytosolic nonspecific dipeptidase [EC:3.4.13.18] (A)	Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; beta-Alanine metabolism (ko00410)	[E]	Amino acid transport and metabolism	Peptidase family M20/M25/M40;; Peptidase dimerisation domain	Cytosolic non-specific dipeptidase GN=CNDP2 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: cytosolic non-specific dipeptidase [Galeopterus variegatus]
ENSG00000133315(MACROD1)	--	10.59675	196	6.35848	120	7.89828	151	3.961412	73	5.923055	111	3.62989	68	6.49E-07	-1.43649513	down	0.96339737	-0.132168872	normal	0.001225244	-1.141745685	down	0.024050279	-0.911103304	normal	[R]	General function prediction only	--	--	--	[BK]	Chromatin structure and dynamics;; Transcription	Macro domain	O-acetyl-ADP-ribose deacetylase MACROD1 GN=MACROD1 OS=Homo sapiens (Human) PE=1 SV=2	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: O-acetyl-ADP-ribose deacetylase MACROD1 [Orcinus orca]
ENSG00000133316(WDR74)	--	19.99105071	487	20.39952033	489	25.9699797	637	23.80602005	584	25.20278608	598	24.46599588	608	0.937067804	0.230549432	normal	0.917129941	0.268133541	normal	0.971653092	-0.075330415	normal	0.623331118	0.129648394	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K14841|0|hsa:54663|WDR74; WD repeat domain 74; K14841 ribosome biogenesis protein NSA1 (A)	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 74 GN=WDR74 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 74 [Equus przewalskii]
ENSG00000133318(RTN3)	--	113.4671467	4327	111.6774917	4253	104.7609469	3965	111.5633679	4333	107.9412883	4140	116.7044329	4492	0.992518312	-0.02882292	normal	0.991621894	-0.060254928	normal	0.986220268	0.171684063	normal	0.928816517	0.026270831	normal	--	--	--	--	--	--	--	Reticulon	Reticulon-3 GN=RTN3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: reticulon-3 [Camelus dromedarius]
ENSG00000133321(RARRES3)	--	0.696286517	7	1.148176299	12	0.105924508	0	3.648177209	38	3.619902827	37	4.37171808	45	0.005346373	2.184015252	up	0.233262849	1.491240265	normal	1.04E-09	4.938801562	up	5.92E-06	2.635409855	up	--	--	--	--	--	--	--	Lecithin retinol acyltransferase	Retinoic acid receptor responder protein 3 GN=RARRES3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: retinoic acid receptor responder protein 3-like [Tupaia chinensis]
ENSG00000133328(HRASLS2)	--	0.0982616	1	0	0	0	0	0.287814	3	0.191577	1	0.484509	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lecithin retinol acyltransferase	HRAS-like suppressor 2 GN=HRASLS2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: HRAS-like suppressor 2 isoform X1 [Equus caballus] 
ENSG00000133392(MYH11)	--	0.0291593	5	0.005697639	1	0.0242401	4	0.030154641	6	0.019421222	3	0.023116063	4	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10352|0|mcf:102129058|MYH11; myosin, heavy chain 11, smooth muscle; K10352 myosin heavy chain (A)"	Tight junction (ko04530)	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; Myosin N-terminal SH3-like domain	Myosin-11 GN=MYH11 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: myosin-11 isoform X1 [Galeopterus variegatus]
ENSG00000133393(FOPNL)	--	37.6486879	1155	34.849467	1021	37.22452603	1065	31.89321188	998	32.65229224	1022	25.77957673	818	0.944393267	-0.241267733	normal	0.979192285	-0.019984642	normal	0.751171021	-0.388341014	normal	0.264835604	-0.213282575	normal	--	--	--	"K16535|6.90057e-118|hsa:123811|FOPNL, C16orf63, FOR20, PHSECRG2; FGFR1OP N-terminal like; K16535 lisH domain-containing protein FOPNL (A)"	--	--	--	FOP N terminal dimerisation domain	LisH domain-containing protein FOPNL GN=FOPNL OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lisH domain-containing protein FOPNL [Erinaceus europaeus]
ENSG00000133398(MED10)	--	34.2902	628	30.9207	580	32.0985	599	41.7965	778	41.4349	754	35.3466	649	0.913223239	0.277562303	normal	0.821923326	0.356268288	normal	0.968864662	0.107111178	normal	0.22119148	0.249696022	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15151|4.71676e-95|ptr:743557|MED10; mediator complex subunit 10; K15151 mediator of RNA polymerase II transcription subunit 10 (A)	--	[K]	Transcription	Transcription factor subunit Med10 of Mediator complex	Mediator of RNA polymerase II transcription subunit 10 GN=MED10 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 10 [Orcinus orca]
ENSG00000133401(PDZD2)	--	0.019018508	5	0.003779151	1	0.018670785	4	0.034423689	9	0.018469417	4	0.018862195	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PDZ domain (Also known as DHR or GLGF);; PDZ domain	Processed PDZ domain-containing protein 2 GN=PDZD2 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: PDZ domain-containing protein 2 [Ceratotherium simum simum]
ENSG00000133422(MORC2)	--	9.860846455	1285	11.008881	1375	10.55039	1389	9.4012457	1268	9.79931	1320	10.25754719	1333	0.981472993	-0.04998571	normal	0.980325684	-0.080230177	normal	0.981536222	-0.06758614	normal	0.788332447	-0.067304958	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; CW-type Zinc Finger;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	MORC family CW-type zinc finger protein 2 GN=MORC2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: MORC family CW-type zinc finger protein 2 [Ceratotherium simum simum]
ENSG00000133424(LARGE1)	--	1.49806485	132	2.620431294	150	1.920099394	156	5.068919655	291	3.411538095	302	3.121623788	268	3.99E-05	1.100808712	up	0.000480061	0.981053867	normal	0.033164105	0.766658292	normal	6.40E-05	0.953849931	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	K09668|0|mcf:101925387|hypothetical protein; K09668 glycosyltransferase-like protein LARGE (A)	--	[G]	Carbohydrate transport and metabolism	Glycosyl-transferase for dystroglycan;; Glycosyl transferase family 8	"Beta-1,3-glucuronyltransferase LARGE {ECO:0000305} GN=LARGE OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	PREDICTED: glycosyltransferase-like protein LARGE1 [Ochotona princeps]
ENSG00000133433(GSTT2B)	--	0	0	0	0	0	0	0.091618202	1	0.1891461	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K00799|2.34318e-178|hsa:653689|GSTT2B, GSTT2P; glutathione S-transferase theta 2B (gene/pseudogene) (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Glutathione S-transferase theta-2B GN=GSTT2B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase theta-2B-like isoform X1 [Galeopterus variegatus]
ENSG00000133454(MYO18B)	--	0.00949761	2	0.00462456	1	0.01365662	2	0.02373393	5	0.05203704	11	0.029338142	5	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	K10362|0|hsa:84700|MYO18B; myosin XVIIIB; K10362 myosin XVIII (A)	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail	Unconventional myosin-XVIIIb GN=MYO18B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: unconventional myosin-XVIIIb isoform X1 [Tupaia chinensis] 
ENSG00000133460(SLC2A11)	--	532.6101964	6680	472.3715355	6108	497.5276743	6490	545.8093866	6896	461.3444661	5845	503.5026025	6422	0.994847619	0.015075995	normal	0.993170251	-0.084902104	normal	0.994565718	-0.023481755	normal	0.918920187	-0.030061291	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08148|0|ptr:458704|SLC2A11; solute carrier family 2 (facilitated glucose transporter), member 11; K08148 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 11 (A)"	--	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 11 GN=SLC2A11 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 11 [Physeter catodon]"
ENSG00000133466(C1QTNF6)	--	5.437568563	434	5.333078384	415	5.477660946	383	6.121967616	404	9.101154077	508	10.84460475	739	0.961119173	-0.13368134	normal	0.915272052	0.269402018	normal	2.98E-05	0.9372273	normal	0.406465021	0.402783581	normal	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	Complement C1q tumor necrosis factor-related protein 6 (Precursor) GN=C1QTNF6 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	hypothetical protein PANDA_002483 [Ailuropoda melanoleuca]
ENSG00000133475(GGT2)	--	0.06803495	3	0.02205703	1	0.114806076	3	0.202422702	9	0.087947828	2	0.029746505	1	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: glutathione catabolic process (GO:0006751);; Molecular Function: glutathione hydrolase activity (GO:0036374);; 	K18592|0|ptr:470168|GGT1; gamma-glutamyltransferase 1; K18592 gamma-glutamyltranspeptidase / glutathione hydrolase / leukotriene-C4 hydrolase [EC:2.3.2.2 3.4.19.13 3.4.19.14] (A)	Taurine and hypotaurine metabolism (ko00430);; Cyanoamino acid metabolism (ko00460);; Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590)	[E]	Amino acid transport and metabolism	Gamma-glutamyltranspeptidase	Inactive gamma-glutamyltranspeptidase 2 (Precursor) GN=GGT2 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: gamma-glutamyltranspeptidase 1 [Camelus dromedarius]
ENSG00000133477(FAM83F)	--	0	0	0.010100991	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF1669);; PLD-like domain	Protein FAM83F GN=FAM83F OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM83F [Ceratotherium simum simum]
ENSG00000133488(SEC14L4)	--	7.303296	643	6.185547231	563	7.198910238	616	5.6912275	494	5.3680658	507	5.3138924	492	0.695801449	-0.410018465	normal	0.955638489	-0.172088346	normal	0.856387181	-0.331650424	normal	0.133576454	-0.308425686	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	"CRAL/TRIO domain;; Golgi-dynamics membrane-trafficking;; CRAL/TRIO, N-terminal domain;; Divergent CRAL/TRIO domain"	SEC14-like protein 4 GN=SEC14L4 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: SEC14-like protein 4 [Camelus dromedarius]
ENSG00000133606(MKRN1)	--	38.3913642	1941	38.77002414	2018	36.9110453	1920	38.88090191	1877	39.16112857	1981	40.8242416	2154	0.984683814	-0.079140021	normal	0.98592664	-0.04808748	normal	0.978964451	0.157503314	normal	0.974455136	0.011440798	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	K15687|0|nle:100581949|MKRN1; makorin ring finger protein 1; K15687 E3 ubiquitin-protein ligase makorin [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase makorin-1 GN=MKRN1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase makorin-1 [Ceratotherium simum simum]
ENSG00000133612(AGAP3)	--	20.23756315	1037	20.0573874	1096	20.36735952	1139	22.87128772	1181	23.07075431	1162	19.64299103	1058	0.969893746	0.156543369	normal	0.979078255	0.062851483	normal	0.975478333	-0.114561698	normal	0.903805973	0.034396407	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: GTP binding (GO:0005525);; 	"K12491|0|ptr:472624|AGAP3; ArfGAP with GTPase domain, ankyrin repeat and PH domain 3; K12491 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3 (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Miro-like protein;; Ras family;; Ankyrin repeats (3 copies);; PH domain;; Ankyrin repeat;; Ankyrin repeats (many copies)	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 GN=AGAP3 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 [Oryctolagus cuniculus]"
ENSG00000133619(KRBA1)	--	3.279637987	227	2.906474906	208	3.491123414	242	2.409247028	204	2.6094067	178	2.5570052	230	0.951503065	-0.183643383	normal	0.935946879	-0.244211234	normal	0.9643928	-0.08114442	normal	0.654839969	-0.166302518	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	KRBA1 family repeat;; KRAB box	Protein KRBA1 GN=KRBA1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein KRBA1 isoform X2 [Oryctolagus cuniculus]
ENSG00000133627(ACTR3B)	--	4.191185849	140	3.487373199	129	4.119529	142	4.821837043	168	4.497992173	156	4.15177152	139	0.946426733	0.229896588	normal	0.941540495	0.250079169	normal	0.967744197	-0.038681106	normal	0.74863308	0.150237861	normal	[Z]	Cytoskeleton	--	K18584|0|pon:100454564|ACTR3B; ARP3 actin-related protein 3 homolog B (yeast); K18584 actin-related protein 3 (A)	--	[Z]	Cytoskeleton	Actin	Actin-related protein 3B GN=ACTR3B OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: actin-related protein 3B isoform X2 [Canis lupus familiaris] 
ENSG00000133636(NTS)	--	0.17442442	3	0.467729148	8	0.466664209	7	2.173040494	38	2.401015	39	1.32655017	23	4.07E-05	3.098536587	up	0.007516246	2.071172514	up	0.710780513	1.518587237	normal	6.06E-05	2.451770529	up	--	--	Molecular Function: neuropeptide hormone activity (GO:0005184);; Cellular Component: extracellular region (GO:0005576);; 	"K05235|1.47508e-102|hsa:4922|NTS, NMN-125, NN, NT, NT/N, NTS1; neurotensin; K05235 neurotensin (A)"	--	--	--	Neurotensin/neuromedin N precursor	Tail peptide (Precursor) GN=NTS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: neurotensin/neuromedin N [Vicugna pacos]
ENSG00000133639(BTG1)	--	43.49691253	1614	43.63353079	1620	38.4014148	1411	71.38322928	2681	76.32381015	2836	97.08129324	3628	0.004837679	0.70077569	normal	0.000577474	0.785875826	normal	3.55E-14	1.353227006	up	2.14E-05	0.956778064	normal	--	--	--	"K14443|7.78838e-126|ptr:452121|BTG1; B-cell translocation gene 1, anti-proliferative; K14443 protein Tob/BTG (A)"	RNA degradation (ko03018)	[TR]	Signal transduction mechanisms;; General function prediction only	BTG family	Protein BTG1 GN=BTG1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	protein BTG1 [Bos taurus] 
ENSG00000133640(LRRIQ1)	--	1.613075082	86	3.31460177	106	2.01165342	89	2.139072808	107	0.974271791	117	1.11247858	117	0.949169251	0.279880303	normal	0.964771223	0.119395932	normal	0.912563674	0.380681807	normal	0.595231857	0.258129171	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat;; IQ calmodulin-binding motif;; Leucine Rich Repeat	Leucine-rich repeat and IQ domain-containing protein 1 GN=LRRIQ1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and IQ domain-containing protein 1 [Pteropus alecto]
ENSG00000133641(C12orf29)	--	9.19855	379	8.675	353	8.776	352	12.1301	509	10.9872	456	8.72551	362	0.754135024	0.393255661	normal	0.843569105	0.34662941	normal	0.968480649	0.031987309	normal	0.262263828	0.269572095	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C12orf29 GN=C12orf29 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C12orf29 homolog [Pteropus alecto] 
ENSG00000133657(ATP13A3)	--	32.7374724	3200	32.96747402	3136	35.69816976	3180	32.25693857	3115	31.27013794	2905	29.24668153	2876	0.989639409	-0.069638114	normal	0.985949079	-0.131747921	normal	0.98441651	-0.153177897	normal	0.579236144	-0.11863353	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; 	"K14951|0|hsa:79572|ATP13A3, AFURS1; ATPase type 13A3; K14951 cation-transporting ATPase 13A3/4/5 [EC:3.6.3.-] (A)"	--	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; P5-type ATPase cation transporter;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus"	Probable cation-transporting ATPase 13A3 GN=ATP13A3 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: probable cation-transporting ATPase 13A3 isoform X2 [Ursus maritimus]
ENSG00000133661(SFTPD)	--	0.291431	5	0.19446266	5	0.11003402	2	0.0383647	1	0.152266	3	0.115307928	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10068|7.47196e-176|hsa:6441|SFTPD, COLEC7, PSP-D, SFTP4, SP-D; surfactant protein D; K10068 pulmonary surfactant-associated protein D (A)"	Phagosome (ko04145)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Collagen triple helix repeat (20 copies);; Lung surfactant protein D coiled-coil trimerisation;; Lectin C-type domain	Pulmonary surfactant-associated protein D (Precursor) GN=SFTPD OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: pulmonary surfactant-associated protein D [Galeopterus variegatus]
ENSG00000133665(DYDC2)	--	0.029701128	1	0	0	0.556797612	2	0.340223022	8	0.375343911	10	0.049748567	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Dpy-30 motif	DPY30 domain-containing protein 2 GN=DYDC2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: DPY30 domain-containing protein 2 [Galeopterus variegatus] 
ENSG00000133678(TMEM254)	--	13.77895842	289	13.404683	310	10.11757621	246	12.61018689	287	9.752055869	258	16.45444638	324	0.96691851	-0.04063424	normal	0.909623092	-0.284798339	normal	0.80445447	0.386965002	normal	0.971889593	0.019173387	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4499)	Transmembrane protein 254 GN=TMEM254 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 254 [Myotis brandtii] 
ENSG00000133687(TMTC1)	--	0.092798978	8	0.03998875	2	0.021162667	2	0.060293575	3	0.05139071	3	0.007001793	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Domain of unknown function (DUF1736);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; NMDA receptor-regulated protein 1;; FAT domain;; Tetratricopeptide repeat;; ChAPs (Chs5p-Arf1p-binding proteins)"	Transmembrane and TPR repeat-containing protein 1 GN=TMTC1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transmembrane and TPR repeat-containing protein 1 isoform X1 [Lipotes vexillifer]
ENSG00000133703(KRAS)	--	15.24369247	1149	13.02427967	955	14.4466086	1055	13.24810382	1018	14.878518	1117	11.93017637	902	0.95828046	-0.205181776	normal	0.957592204	0.204330563	normal	0.945794497	-0.233971988	normal	0.755656779	-0.078234792	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07827|5.22029e-129|ptr:473387|KRAS; Kirsten rat sarcoma viral oncogene homolog; K07827 GTPase KRas (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; Dorso-ventral axis formation (ko04320);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Tight junction (ko04530);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Aldosterone-regulated sodium reabsorption (ko04960);; Alcoholism (ko05034);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	"GTPase KRas, N-terminally processed (Precursor) GN=KRAS OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	PREDICTED: GTPase KRas isoform 1 [Ovis aries] 
ENSG00000133704(IPO8)	--	18.68255762	1539	18.82765212	1481	18.07399687	1532	20.97150379	1806	20.4738969	1725	18.60740304	1673	0.968131357	0.199788134	normal	0.967610877	0.198410293	normal	0.980041769	0.118617626	normal	0.370660252	0.171731354	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	K18755|0|pps:100974188|IPO8; importin 8; K18755 importin-8 (A)	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Importin-beta N-terminal domain;; Cse1	Importin-8 GN=IPO8 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin-8 [Tupaia chinensis]
ENSG00000133706(LARS)	--	47.09637991	3641	45.27456163	3661	43.28861469	3606	47.99577021	3863	45.424295	3555	50.47171372	3749	0.991252494	0.054532332	normal	0.990515191	-0.063788031	normal	0.991223177	0.047795327	normal	0.971083755	0.012520038	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01869|0|hsa:51520|LARS, HSPC192, ILFS1, LARS1, LEURS, LEUS, LFIS, LRS, PIG44, RNTLS, hr025Cl; leucyl-tRNA synthetase (EC:6.1.1.4); K01869 leucyl-tRNA synthetase [EC:6.1.1.4] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (I, L, M and V);; tRNA synthetases class I (M);; Anticodon-binding domain of tRNA;; tRNA synthetases class I (C) catalytic domain"	"Leucine--tRNA ligase, cytoplasmic GN=LARS OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: leucine--tRNA ligase, cytoplasmic [Oryctolagus cuniculus]"
ENSG00000133731(IMPA1)	--	18.73983112	631	18.95275942	642	21.5581433	640	16.892619	578	16.24071682	546	18.29546909	629	0.960879277	-0.157003157	normal	0.926391756	-0.254448143	normal	0.973909801	-0.033224138	normal	0.550641055	-0.146971553	normal	[G]	Carbohydrate transport and metabolism	Biological Process: phosphatidylinositol phosphorylation (GO:0046854);; 	"K01092|0|hsa:3612|IMPA1, IMP, IMPA; inositol(myo)-1(or 4)-monophosphatase 1 (EC:3.1.3.25 3.1.3.94); K01092 myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[G]	Carbohydrate transport and metabolism	Inositol monophosphatase family	Inositol monophosphatase 1 GN=IMPA1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: inositol monophosphatase 1 isoform X1 [Loxodonta africana]
ENSG00000133739(LRRCC1)	--	2.500128305	197	2.014075638	156	2.13449305	163	1.677518942	132	2.107218859	166	1.349985	107	0.414808898	-0.602705799	normal	0.964736946	0.067575563	normal	0.501810694	-0.608532478	normal	0.295867467	-0.371118619	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16475|0|hsa:85444|LRRCC1, CLERC, SAP2, VFL1; leucine rich repeat and coiled-coil centrosomal protein 1; K16475 leucine-rich repeat and coiled-coil domain-containing protein 1 (A)"	--	--	--	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich Repeat	Leucine-rich repeat and coiled-coil domain-containing protein 1 GN=LRRCC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and coiled-coil domain-containing protein 1 isoform X1 [Tupaia chinensis]
ENSG00000133740(E2F5)	--	12.97913228	328	12.420662	316	12.52830454	329	10.04964636	270	10.132573	255	9.659617203	246	0.891049142	-0.30996531	normal	0.875927069	-0.329096858	normal	0.730035555	-0.425450901	normal	0.1626484	-0.357138303	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K04682|0|ptr:747256|E2F5; E2F transcription factor 5, p130-binding; K04682 transcription factor E2F4/5 (A)"	Cell cycle (ko04110);; TGF-beta signaling pathway (ko04350)	[K]	Transcription	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F5 GN=E2F5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor E2F5 isoform X1 [Sus scrofa]
ENSG00000133773(CCDC59)	--	15.27003	318	18.35784	384	16.74836	369	15.28823	367	15.68216	364	20.80641	382	0.9521549	0.175132918	normal	0.963824391	-0.098197145	normal	0.968536414	0.04149324	normal	0.935206041	0.034471423	normal	--	--	--	--	--	[S]	Function unknown	rRNA processing	Thyroid transcription factor 1-associated protein 26 GN=CCDC59 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: thyroid transcription factor 1-associated protein 26 [Ceratotherium simum simum]
ENSG00000133789(SWAP70)	--	13.47616467	1175	18.41521861	1609	16.48492344	1463	17.30865191	1527	15.05616377	1341	17.68636938	1555	0.853034349	0.346808294	normal	0.929315706	-0.283988805	normal	0.982105497	0.079613535	normal	0.908434478	0.037412489	normal	--	--	--	--	--	--	--	PH domain	Switch-associated protein 70 GN=SWAP70 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: switch-associated protein 70 [Galeopterus variegatus]
ENSG00000133794(ARNTL)	--	6.023632489	241	4.218921279	211	5.004748733	184	9.607749074	457	9.756978064	448	11.2065023	328	0.000539637	0.888151808	normal	1.14E-05	1.059500005	up	0.006833929	0.820578893	normal	7.89E-05	0.93267265	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K02296|0|ptr:451034|ARNTL; aryl hydrocarbon receptor nuclear translocator-like; K02296 aryl hydrocarbon receptor nuclear translocator-like protein 1 (A)	Circadian rhythm (ko04710);; Dopaminergic synapse (ko04728);; Herpes simplex infection (ko05168)	[K]	Transcription	PAS domain;; PAS fold;; PAS fold;; Helix-loop-helix DNA-binding domain;; PAS domain;; PAS fold	Aryl hydrocarbon receptor nuclear translocator-like protein 1 GN=ARNTL OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: aryl hydrocarbon receptor nuclear translocator-like protein 1 isoform X4 [Pteropus alecto]
ENSG00000133805(AMPD3)	--	3.955995168	288	4.521742942	327	5.155394341	370	5.6217172	402	4.281114077	311	5.791769987	414	0.64170841	0.448262207	normal	0.963241148	-0.093359816	normal	0.957481734	0.153221735	normal	0.555175939	0.173392176	normal	--	--	Molecular Function: deaminase activity (GO:0019239);; 	K01490|0|hsa:272|AMPD3; adenosine monophosphate deaminase 3 (EC:3.5.4.6); K01490 AMP deaminase [EC:3.5.4.6] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	Adenosine/AMP deaminase	AMP deaminase 3 GN=AMPD3 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: AMP deaminase 3 isoform X1 [Galeopterus variegatus]
ENSG00000133808(MICALCL)	--	0.460665437	31	0.917941572	14	0.235828886	15	0.142685449	9	0.272721323	17	0.141057981	9	0.241352483	-1.654523104	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF3585)	MICAL C-terminal-like protein GN=MICALCL OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: MICAL C-terminal-like protein [Galeopterus variegatus]
ENSG00000133812(SBF2)	--	12.87938405	1742	11.67663995	1623	12.77491162	1594	10.07624857	1365	11.22671464	1469	11.79407405	1652	0.788123647	-0.382293923	normal	0.973514729	-0.165093384	normal	0.984329421	0.043230326	normal	0.394686977	-0.165311688	normal	--	--	--	"K18061|0|hsa:81846|SBF2, CMT4B2, DENND7B, MTMR13; SET binding factor 2; K18061 myotubularin-related protein 5/13 (A)"	--	[R]	General function prediction only	Myotubularin protein;; Myotubularin-like phosphatase domain;; DENN (AEX-3) domain;; uDENN domain;; dDENN domain;; PH domain;; GRAM domain	Myotubularin-related protein 13 GN=SBF2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: myotubularin-related protein 13 isoform X2 [Sus scrofa]
ENSG00000133816(MICAL2)	--	30.51400784	4064	24.3954523	3254	33.165716	4053	22.73749591	3048	18.48521681	2488	14.045797	1751	0.660646551	-0.445674436	normal	0.780576632	-0.408436521	normal	1.87E-11	-1.218390143	down	0.010877846	-0.664530221	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; Molecular Function: FAD binding (GO:0071949);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Calponin homology (CH) domain;; CAMSAP CH domain;; LIM domain;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase;; Putative NAD(P)-binding	Protein-methionine sulfoxide oxidase MICAL2 GN=MICAL2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: protein-methionine sulfoxide oxidase MICAL2 isoform X2 [Felis catus] 
ENSG00000133818(RRAS2)	--	44.63087538	649	48.41936648	749	44.57049215	727	57.30165727	1020	47.75244713	882	46.45071	909	0.046887494	0.620266192	normal	0.949903996	0.213987873	normal	0.882973535	0.31344923	normal	0.025784199	0.38207131	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07830|3.24328e-141|rno:365355|Rras2; related RAS viral (r-ras) oncogene homolog 2; K07830 Ras-related protein R-Ras2 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; Tight junction (ko04530);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein R-Ras2 (Precursor) GN=RRAS2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein R-Ras2 [Orycteropus afer afer]
ENSG00000133835(HSD17B4)	--	44.51821321	2214	44.65323756	2259	41.8427353	2077	44.23972254	2229	44.00809739	2178	45.36304286	2247	0.987713296	-0.021076292	normal	0.986091268	-0.07405638	normal	0.984562457	0.105133854	normal	0.999953487	0.001418667	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K12405|0|hsa:3295|HSD17B4, DBP, MFE-2, MPF-2, PRLTS1, SDR8C1; hydroxysteroid (17-beta) dehydrogenase 4 (EC:4.2.1.107 4.2.1.119 1.1.1.n12); K12405 3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase [EC:1.1.1.35 4.2.1.107] (A)"	Primary bile acid biosynthesis (ko00120);; Peroxisome (ko04146)	--	--	MaoC like domain;; short chain dehydrogenase;; SCP-2 sterol transfer family;; KR domain;; N-terminal half of MaoC dehydratase	Enoyl-CoA hydratase 2 GN=HSD17B4 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: peroxisomal multifunctional enzyme type 2 [Galeopterus variegatus]
ENSG00000133858(ZFC3H1)	--	8.183840003	1165	9.0579293	1262	9.2192911	1277	8.91254	1272	8.477612	1184	7.841219	1093	0.978415702	0.095815501	normal	0.976598182	-0.113329147	normal	0.950654609	-0.232458685	normal	0.730012906	-0.083242315	normal	--	--	--	--	--	[S]	Function unknown	Tetratricopeptide repeat;; Putative zinc-finger domain;; Tetratricopeptide repeat	Zinc finger C3H1 domain-containing protein GN=ZFC3H1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: zinc finger C3H1 domain-containing protein [Panthera tigris altaica]
ENSG00000133863(TEX15)	--	0.537627349	108	0.610404445	118	0.521437287	102	0.4053245	84	0.36209799	75	0.254260352	54	0.915673977	-0.387138812	normal	0.546348663	-0.664474833	normal	0.157587493	-0.90704091	normal	0.106475561	-0.645475738	normal	--	--	--	--	--	--	--	Testis expressed sequence 15;; Protein of unknown function (DUF3715)	Testis-expressed sequence 15 protein GN=TEX15 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: testis-expressed sequence 15 protein [Equus przewalskii]
ENSG00000133872(SARAF)	--	104.5048992	3241	94.97685488	2916	88.57189763	2738	136.5178543	4296	147.1183341	4577	138.0088691	4276	0.868261216	0.375567633	normal	0.04357057	0.628722696	normal	0.029807757	0.634565236	normal	0.000183052	0.542538605	normal	--	--	Cellular Component: integral component of endoplasmic reticulum membrane (GO:0030176);; Biological Process: regulation of store-operated calcium entry (GO:2001256);; 	--	--	--	--	Protein of unknown function (DUF1183)	Store-operated calcium entry-associated regulatory factor (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: store-operated calcium entry-associated regulatory factor-like [Chrysochloris asiatica]
ENSG00000133874(RNF122)	--	3.52845	112	4.74348	151	4.021357	128	3.481151	109	4.24515	132	3.592262	114	0.968918233	-0.069042711	normal	0.949937851	-0.213151937	normal	0.960249087	-0.173231412	normal	0.748749669	-0.160429699	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metal ion binding (GO:0046872);; 	K15699|4.8774e-111|ptr:746203|RNF122; ring finger protein 122; K15699 RING finger protein 122 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 122 GN=RNF122 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 122 isoform X4 [Felis catus] 
ENSG00000133878(DUSP26)	--	0.0613408	2	0.267606	9	0.119436153	0	0	0	0.1822007	5	0.120916042	4	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14165|6.95215e-130|ptr:464104|DUSP26; dual specificity phosphatase 26 (putative); K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 26 GN=DUSP26 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 26 isoform X1 [Equus caballus] 
ENSG00000133884(DPF2)	--	14.27771199	758	14.37542956	744	16.0325982	799	15.35160756	783	15.31100651	790	17.39378726	911	0.976400723	0.015950386	normal	0.974159835	0.064995258	normal	0.960883299	0.180643698	normal	0.728697096	0.089773477	normal	--	--	--	"K13196|0|ngi:103724981|Dpf2; D4, zinc and double PHD fingers family 2; K13196 zinc finger protein ubi-d4 (A)"	--	[K]	Transcription	N-terminal domain of DPF2/REQ.;; PHD-finger	Zinc finger protein ubi-d4 GN=DPF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein ubi-d4 isoform 1 [Dasypus novemcinctus]
ENSG00000133895(MEN1)	--	30.17009445	1082	28.19393137	1030	30.95927394	1211	29.5714484	1170	27.44296458	1028	27.46909557	1043	0.978408623	0.081863966	normal	0.979211147	-0.024195072	normal	0.953073636	-0.223450172	normal	0.830156026	-0.057366952	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K14970|0|hsa:4221|MEN1, MEAI, SCG2; multiple endocrine neoplasia I; K14970 menin (A)"	Transcriptional misregulation in cancer (ko05202)	--	--	Menin	Menin GN=MEN1 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	menin [Canis lupus familiaris] 
ENSG00000133935(C14orf1)	--	24.752154	1079	21.947912	954	24.60802	1066	13.344605	586	14.260813	620	22.31996	981	2.30E-05	-0.909767474	normal	0.035993384	-0.641875044	normal	0.972990474	-0.127984509	normal	0.072640106	-0.522379794	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Erg28 like protein	Probable ergosterol biosynthetic protein 28 GN=C14orf1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: probable ergosterol biosynthetic protein 28 [Galeopterus variegatus]
ENSG00000133937(GSC)	--	0.562134	10	0.265985	5	0.362101	6	0.217816	4	0.268879	4	0.327934	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09324|2.67214e-153|hsa:145258|GSC, SAMS; goosecoid homeobox; K09324 homeobox protein goosecoid (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein goosecoid GN=GSC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein goosecoid [Ceratotherium simum simum]
ENSG00000133943(C14orf159)	--	10.71095188	412	11.33456202	439	14.31718426	505	12.0679515	538	12.83533605	575	12.51297767	543	0.827210805	0.35297482	normal	0.806009796	0.366807416	normal	0.968005969	0.096099787	normal	0.227578509	0.267521967	normal	[S]	Function unknown	--	--	--	--	--	Domain of unknown function (DUF4392);; Protein of unknown function (DUF1445)	"UPF0317 protein C14orf159, mitochondrial (Precursor) GN=C14orf159 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: UPF0317 protein C14orf159 homolog, mitochondrial isoform X1 [Tupaia chinensis] "
ENSG00000133961(NUMB)	--	31.21196959	1482	26.69964174	1462	28.32286099	1452	35.24655229	1676	25.00700148	1347	35.83419604	1581	0.97675041	0.146501558	normal	0.975683691	-0.139469664	normal	0.979722363	0.114390267	normal	0.866978052	0.045209853	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06057|0|hsa:8650|NUMB, C14orf41, S171, c14_5527; numb homolog (Drosophila); K06057 numb (A)"	Notch signaling pathway (ko04330)	[T]	Signal transduction mechanisms	NUMB domain;; Phosphotyrosine interaction domain (PTB/PID);; Phosphotyrosine-binding domain	Protein numb homolog GN=NUMB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein numb homolog isoform X1 [Sus scrofa]
ENSG00000133962(CATSPERB)	--	2.883028388	157	2.901988985	175	1.966731814	121	3.367901294	202	5.251578616	278	6.614414738	362	0.900702596	0.329906056	normal	0.18611978	0.641866273	normal	3.36E-11	1.56085465	up	0.045816189	0.874300108	normal	--	--	Cellular Component: CatSper complex (GO:0036128);; 	"K16893|0|hsa:79820|CATSPERB, C14orf161, CatSper(beta); catsper channel auxiliary subunit beta; K16893 cation channel sperm-associated protein subunit beta (A)"	--	--	--	Cation channel sperm-associated protein subunit beta protein family	Cation channel sperm-associated protein subunit beta GN=CATSPERB OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: cation channel sperm-associated protein subunit beta [Ceratotherium simum simum]
ENSG00000133983(COX16)	--	35.37652822	1738	44.58295003	1936	40.8128659	1897	51.28411554	2136	41.93768001	1882	40.3139	1912	0.947377435	0.266438541	normal	0.985037861	-0.062189609	normal	0.986433185	0.003068966	normal	0.778202521	0.068564601	normal	--	--	Cellular Component: mitochondrial membrane (GO:0031966);; 	K18182|2.0885e-71|pon:100172069|COX16; COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) pseudogene; K18182 cytochrome c oxidase assembly protein subunit 16 (A)	--	--	--	Cytochrome c oxidase assembly protein COX16	"Cytochrome c oxidase assembly protein COX16 homolog, mitochondrial (Precursor) GN=COX16 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: cytochrome c oxidase assembly protein COX16 homolog, mitochondrial [Galeopterus variegatus]"
ENSG00000133985(TTC9)	--	1.17638	115	1.3133	128	1.37845	134	2.50572	244	2.26777	221	2.13152	209	0.000366865	1.044623206	up	0.070007435	0.759567365	normal	0.325741504	0.627265374	normal	0.002608796	0.816667531	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 9A GN=TTC9 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 9A [Sus scrofa]
ENSG00000133997(MED6)	--	13.53513	456	20.989025	605	14.99008	506	16.94047445	538	16.37443693	549	16.321775	569	0.94542773	0.207097137	normal	0.958955816	-0.161132524	normal	0.958908226	0.160547107	normal	0.856654246	0.058536647	normal	[K]	Transcription	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15128|4.06736e-168|lve:103083102|MED6; mediator complex subunit 6; K15128 mediator of RNA polymerase II transcription subunit 6 (A)	--	[K]	Transcription	MED6 mediator sub complex component	Mediator of RNA polymerase II transcription subunit 6 GN=MED6 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 6 isoform X1 [Lipotes vexillifer]
ENSG00000134001(EIF2S1)	--	35.45915	2117	37.57397037	2291	37.55091	2152	43.02655001	2662	36.77781	2401	32.57938214	2035	0.933624202	0.299462878	normal	0.987458487	0.046201596	normal	0.985168565	-0.088876489	normal	0.683169758	0.091674028	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation initiation factor activity (GO:0003743);; 	"K03237|0|ptr:452980|EIF2S1; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; K03237 translation initiation factor 2 subunit 1 (A)"	RNA transport (ko03013);; Protein processing in endoplasmic reticulum (ko04141);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[J]	"Translation, ribosomal structure and biogenesis"	Eukaryotic translation initiation factor 2 alpha subunit;; S1 RNA binding domain	Eukaryotic translation initiation factor 2 subunit 1 GN=EIF2S1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	Eukaryotic translation initiation factor 2 subunit 1 [Myotis brandtii]
ENSG00000134007(ADAM20)	--	0.0617916	3	0.0203261	1	0	0	0.0410629	2	0.0602455	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K08609|0|hsa:8748|ADAM20; ADAM metallopeptidase domain 20; K08609 disintegrin and metalloproteinase domain-containing protein 20 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Reprolysin family propeptide;; Disintegrin;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 20 (Precursor) GN=ADAM20 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: disintegrin and metalloproteinase domain-containing protein 20-like, partial [Ceratotherium simum simum]"
ENSG00000134013(LOXL2)	--	208.3052216	16265	177.3036072	13992	168.7223498	13406	180.1521858	13979	134.4407858	10763	143.9506305	11404	0.990121044	-0.249316491	normal	0.9185545	-0.399899054	normal	0.989174399	-0.241600752	normal	0.129255448	-0.294671698	normal	--	--	"Molecular Function: scavenger receptor activity (GO:0005044);; Molecular Function: copper ion binding (GO:0005507);; Cellular Component: membrane (GO:0016020);; Molecular Function: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (GO:0016641);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00280|0|hsa:4017|LOXL2, LOR2, WS9-14; lysyl oxidase-like 2 (EC:1.4.3.-); K00280 lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] (A)"	--	--	--	Lysyl oxidase;; Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	Lysyl oxidase homolog 2 (Precursor) GN=LOXL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: lysyl oxidase homolog 2 [Galeopterus variegatus]
ENSG00000134014(ELP3)	--	16.57783405	896	17.60604452	866	18.59510724	921	15.76230903	850	14.84054921	830	16.79341365	892	0.97310388	-0.1066803	normal	0.974320709	-0.082535007	normal	0.977329873	-0.054358187	normal	0.748610372	-0.081928015	normal	[KB]	Transcription;; Chromatin structure and dynamics	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	K07739|0|ptr:464081|ELP3; elongator acetyltransferase complex subunit 3; K07739 elongator complex protein 3 [EC:2.3.1.48] (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	Radical SAM superfamily;; Acetyltransferase (GNAT) family	Elongator complex protein 3 GN=ELP3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: elongator complex protein 3 [Oryctolagus cuniculus]
ENSG00000134020(PEBP4)	--	0.139611	2	0	0	0	0	0.28061	1	0.298126	0	0.592343	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Phosphatidylethanolamine-binding protein	Phosphatidylethanolamine-binding protein 4 (Precursor) GN=PEBP4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: phosphatidylethanolamine-binding protein 4 isoform X1 [Equus caballus] 
ENSG00000134030(CTIF)	--	6.43367051	750	5.63051143	648	6.209107759	773	8.273864588	833	8.967802264	968	8.225194057	966	0.970244046	0.120359615	normal	0.172688486	0.556517459	normal	0.885220983	0.312714989	normal	0.064669282	0.329468438	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	MIF4G domain	CBP80/20-dependent translation initiation factor GN=CTIF OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: CBP80/20-dependent translation initiation factor isoform X1 [Ursus maritimus] 
ENSG00000134042(MRO)	--	0.039549408	2	0	0	0	0	0.01229113	1	0.133949825	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	HEAT repeat	Protein maestro GN=MRO OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein maestro isoform X1 [Tupaia chinensis] 
ENSG00000134046(MBD2)	--	11.15018584	912	12.99007396	1081	12.51901918	1028	14.77433776	1228	13.1850503	1076	11.46774609	950	0.727913031	0.397793222	normal	0.979692767	-0.028075635	normal	0.973236932	-0.12194562	normal	0.725058255	0.085234943	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	K11590|0|tup:102481344|MBD2; methyl-CpG binding domain protein 2; K11590 methyl-CpG-binding domain protein 2 (A)	--	[KB]	Transcription;; Chromatin structure and dynamics	C-terminal domain of methyl-CpG binding protein 2 and 3;; Methyl-CpG binding domain	Methyl-CpG-binding domain protein 2 GN=MBD2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: methyl-CpG-binding domain protein 2 [Tupaia chinensis]
ENSG00000134049(IER3IP1)	--	13.1586434	667	12.68810102	678	14.47705833	734	13.45413782	726	12.62761157	657	13.68529115	703	0.971627368	0.091249025	normal	0.972359158	-0.066667391	normal	0.973675128	-0.070398593	normal	0.967095709	-0.016321908	normal	--	--	--	--	--	[S]	Function unknown	Yos1-like	Immediate early response 3-interacting protein 1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: immediate early response 3-interacting protein 1 [Condylura cristata] 
ENSG00000134056(MRPS36)	--	20.677964	319	21.62968	333	23.917574	364	20.889865	332	18.453737	284	23.0741	359	0.967930513	0.026668649	normal	0.926922942	-0.249827749	normal	0.968672128	-0.028128373	normal	0.825301222	-0.080259053	normal	--	--	--	K17414|6.09848e-69|ptr:742363|MRPS36; mitochondrial ribosomal protein S36; K17414 small subunit ribosomal protein S36 (A)	--	--	--	Protein of unknown function (DUF2638)	"28S ribosomal protein S36, mitochondrial GN=MRPS36 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S36, mitochondrial [Felis catus] "
ENSG00000134057(CCNB1)	--	117.3425254	3413	110.9196941	3130	117.5298099	3431	116.1498239	3409	113.726941	3340	85.25992428	2605	0.990953917	-0.032509435	normal	0.989463744	0.072225104	normal	0.781464738	-0.405431434	normal	0.598083532	-0.114404542	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	"K05868|0|hsa:891|CCNB1, CCNB; cyclin B1; K05868 cyclin B (A)"	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Oocyte meiosis (ko04114);; p53 signaling pathway (ko04115);; Progesterone-mediated oocyte maturation (ko04914)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G2/mitotic-specific cyclin-B1 GN=CCNB1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: G2/mitotic-specific cyclin-B1 [Ceratotherium simum simum]
ENSG00000134058(CDK7)	--	29.50012819	633	31.56019958	682	33.68091473	712	33.36572799	737	26.7724693	593	28.690869	604	0.955252091	0.188203212	normal	0.942510032	-0.222636248	normal	0.933016761	-0.245054339	normal	0.744401532	-0.089504104	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02202|0|ptr:462378|CDK7; cyclin-dependent kinase 7; K02202 cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23] (A)	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420);; Cell cycle (ko04110)	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Seadornavirus VP7	Cyclin-dependent kinase 7 GN=CDK7 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 7 [Orycteropus afer afer]
ENSG00000134070(IRAK2)	--	14.2233	965	14.4234	980	12.8254	870	14.3767	968	16.0473	1079	23.1986	1570	0.978895022	-0.02631233	normal	0.973816222	0.117242187	normal	0.000106562	0.842280383	normal	0.402314023	0.341721769	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; 	"K04731|0|hsa:3656|IRAK2, IRAK-2; interleukin-1 receptor-associated kinase 2; K04731 interleukin-1 receptor-associated kinase 2 [EC:2.7.11.1] (A)"	Apoptosis (ko04210);; Neurotrophin signaling pathway (ko04722);; Tuberculosis (ko05152)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Death domain	Interleukin-1 receptor-associated kinase-like 2 GN=IRAK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor-associated kinase-like 2 isoform 1 [Ceratotherium simum simum]
ENSG00000134072(CAMK1)	--	12.73621	360	12.2067	313	13.154003	362	13.1561393	358	11.305396	323	13.45849002	360	0.968212221	-0.038703938	normal	0.96694929	0.023831603	normal	0.96889374	-0.0162163	normal	0.982154068	-0.012718414	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08794|0|hsa:8536|CAMK1, CAMKI; calcium/calmodulin-dependent protein kinase I (EC:2.7.11.17); K08794 calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] (A)"	Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Calcium/calmodulin-dependent protein kinase type 1 GN=CAMK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	Calcium/calmodulin-dependent protein kinase type 1 [Pteropus alecto]
ENSG00000134077(THUMPD3)	--	24.38876784	1304	24.9892	1338	25.11262	1271	23.692208	1329	25.575955	1267	25.648662	1305	0.982647896	-0.003431024	normal	0.978577125	-0.099972012	normal	0.982165779	0.029759389	normal	0.932682156	-0.025765287	normal	[L]	"Replication, recombination and repair"	Molecular Function: RNA binding (GO:0003723);; 	--	--	--	--	Putative RNA methylase family UPF0020;; Methyltransferase domain;; THUMP domain	THUMP domain-containing protein 3 GN=THUMPD3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: THUMP domain containing 3 [Tupaia chinensis]
ENSG00000134086(VHL)	--	25.84569471	1595	25.931709	1578	23.69733121	1451	27.41804	1609	27.834529	1689	27.3146	1646	0.984626739	-0.0182069	normal	0.982757647	0.076574625	normal	0.972383069	0.173455537	normal	0.753839695	0.075284945	normal	--	--	--	"K03871|7.37663e-112|ptr:749769|VHL; von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase; K03871 von Hippel-Lindau disease tumor supressor (A)"	HIF-1 signaling pathway (ko04066);; Ubiquitin mediated proteolysis (ko04120);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[O]	"Posttranslational modification, protein turnover, chaperones"	von Hippel-Lindau disease tumour suppressor protein	Von Hippel-Lindau disease tumor suppressor GN=VHL OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: von Hippel-Lindau disease tumor suppressor [Myotis lucifugus]
ENSG00000134107(BHLHE40)	--	69.46312263	4336	61.5033093	3820	54.45627	3377	77.9515721	4849	69.700858	4323	81.97399655	5145	0.990009497	0.13044651	normal	0.98696708	0.156975196	normal	0.075442173	0.598918601	normal	0.083883881	0.290597906	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K03729|0|ptr:460136|BHLHE40, BHLHB2; basic helix-loop-helix family, member e40; K03729 class B basic helix-loop-helix protein 2 (A)"	Circadian rhythm (ko04710)	[K]	Transcription	Helix-loop-helix DNA-binding domain;; Hairy Orange	Class E basic helix-loop-helix protein 40 GN=BHLHE40 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: class E basic helix-loop-helix protein 40 [Ceratotherium simum simum]
ENSG00000134108(ARL8B)	--	41.51832342	1761	49.68851267	2104	39.093392	1635	43.5823912	1874	44.65051126	1888	60.57953	2569	0.984992599	0.05884401	normal	0.975517082	-0.177567683	normal	0.021585646	0.643146301	normal	0.607295183	0.182414905	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07955|8.39877e-136|tup:102475308|ARL8B; ADP-ribosylation factor-like 8B; K07955 ADP-ribosylation factor-like protein 8 (A)	--	[R]	General function prediction only	ADP-ribosylation factor family;; Ras family;; Miro-like protein;; Gtr1/RagA G protein conserved region;; Signal recognition particle receptor beta subunit;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	ADP-ribosylation factor-like protein 8B GN=ARL8B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: ADP-ribosylation factor-like 8B [Trichechus manatus latirostris]
ENSG00000134109(EDEM1)	--	24.760609	2402	24.56882	2405	21.511078	2076	24.242909	2348	22.471076	2156	28.65275	2779	0.987423726	-0.06359486	normal	0.977334419	-0.17898733	normal	0.740259098	0.412207533	normal	0.82927863	0.060513913	normal	--	--	"Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: membrane (GO:0016020);; "	"K10084|0|hsa:9695|EDEM1, EDEM; ER degradation enhancer, mannosidase alpha-like 1; K10084 ER degradation enhancer, mannosidase alpha-like 1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 47	ER degradation-enhancing alpha-mannosidase-like protein 1 GN=EDEM1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	ER degradation-enhancing alpha-mannosidase-like protein 1 [Bos taurus] 
ENSG00000134121(CHL1)	--	0	0	0	0	0	0	0.009577711	1	0.05272306	4	0.03817384	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K06758|0|pps:100991475|CHL1; cell adhesion molecule L1-like; K06758 L1 cell adhesion molecule like protein (A)	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Bravo-like intracellular region;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Processed neural cell adhesion molecule L1-like protein (Precursor) GN=CHL1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: neural cell adhesion molecule L1-like protein isoform X1 [Ursus maritimus]
ENSG00000134138(MEIS2)	--	4.773228526	253	4.47748257	224	5.044178486	274	4.391790117	254	6.94994016	285	6.415592917	261	0.966931578	-0.024989694	normal	0.885362504	0.324092797	normal	0.964813106	-0.077976513	normal	0.868288796	0.070412178	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K16670|0|ocu:100338587|MEIS2; Meis homeobox 2; K16670 homeobox protein Meis2 (A)	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein Meis2 GN=MEIS2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein Meis2 isoform X1 [Oryctolagus cuniculus]
ENSG00000134146(DPH6)	--	9.475283225	156	6.492186411	157	4.354122049	115	9.067278281	159	7.49505675	162	7.846634818	141	0.967673873	-0.003319148	normal	0.966131743	0.023579108	normal	0.93774107	0.282410562	normal	0.867818769	0.08825714	normal	[R]	General function prediction only	--	K06927|0|ggo:101153919|ATPBD4; ATP-binding domain-containing protein 4 isoform 1; K06927 diphthine-ammonia ligase [EC:6.3.1.14] (A)	--	[R]	General function prediction only	ATP-binding region	Diphthine--ammonia ligase GN=DPH6 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: diphthine--ammonia ligase isoform X1 [Mustela putorius furo] 
ENSG00000134152(KATNBL1)	--	19.18572584	618	21.112034	654	21.76009697	704	21.29244732	688	19.12586377	565	23.56369832	703	0.967288243	0.123677963	normal	0.937982739	-0.231888819	normal	0.975503559	-0.010319997	normal	0.911176514	-0.03571717	normal	--	--	--	--	--	--	--	con80 domain of Katanin	KATNB1-like protein 1 GN=KATNBL1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: KATNB1-like protein 1 [Odobenus rosmarus divergens]
ENSG00000134153(EMC7)	--	71.21611584	1254	70.36203749	1280	61.3369217	1104	77.73472515	1394	69.25695654	1204	75.968779	1318	0.977180194	0.121719464	normal	0.977149948	-0.109601432	normal	0.944662941	0.247008705	normal	0.722056836	0.084569749	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF2012)	ER membrane protein complex subunit 7 (Precursor) GN=EMC7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ER membrane protein complex subunit 7 [Condylura cristata]
ENSG00000134183(GNAT2)	--	0.0851418	2	0	0	0	0	0.0421088	1	0.166277144	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04631|0|ptr:469402|GNAT2; guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2; K04631 guanine nucleotide-binding protein G(t) subunit alpha (A)"	Phototransduction (ko04744)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Guanine nucleotide-binding protein G(t) subunit alpha-2 GN=GNAT2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(t) subunit alpha-2 isoform X1 [Galeopterus variegatus]
ENSG00000134184(GSTM1)	--	7.817397031	208	6.212880786	167	5.7919802	147	3.87057302	98	6.432416963	160	5.679026396	142	0.000264041	-1.104385445	down	0.96387698	-0.082439971	normal	0.967015966	-0.057613575	normal	0.265375946	-0.404444251	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K00799|6.16883e-139|hsa:2944|GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1; glutathione S-transferase mu 1 (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain"	Glutathione S-transferase Mu 1 GN=GSTM1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase Mu 1 [Bison bison bison]
ENSG00000134186(PRPF38B)	--	12.144705	788	13.61792	958	15.10606	991	18.086112	1215	19.537655	1321	17.674234	1199	0.074193263	0.592918957	normal	0.597561904	0.441510516	normal	0.931428861	0.266213398	normal	0.006585098	0.427526914	normal	--	--	--	K12850|1.84973e-132|pon:100433336|PRPF38B; pre-mRNA processing factor 38B; K12850 pre-mRNA-splicing factor 38B (A)	Spliceosome (ko03040)	[R]	General function prediction only	PRP38 family	Pre-mRNA-splicing factor 38B GN=PRPF38B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pre-mRNA-splicing factor 38B [Loxodonta africana]
ENSG00000134193(REG4)	--	0	0	2.814359193	63	2.80725316	64	0	0	0	0	0	0	--	--	--	2.49E-14	-5.425269058	down	1.70E-14	-5.441016135	down	--	--	--	--	--	--	--	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	Regenerating islet-derived protein 4 (Precursor) GN=REG4 OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: regenerating islet-derived protein 4-like isoform X1 [Tupaia chinensis] 
ENSG00000134198(TSPAN2)	--	0.969666741	46	0.382602345	18	0.759768606	35	2.305451042	84	2.41981224	88	0.658154975	30	0.478299951	0.817447729	normal	2.79E-07	2.17728764	up	0.980999236	-0.220388347	normal	0.251337541	1.005788066	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17354|6.40905e-140|pps:100967588|TSPAN2; tetraspanin 2; K17354 tetraspanin-2 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-2 GN=TSPAN2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: tetraspanin-2 isoform X1 [Orycteropus afer afer]
ENSG00000134202(GSTM3)	--	7.646186239	168	4.403739091	115	3.595291329	90	5.991060038	133	6.479248054	162	2.08151539	63	0.890072292	-0.364114827	normal	0.793992293	0.467728515	normal	0.869904205	-0.512517239	normal	0.945361045	-0.082578502	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K00799|9.92886e-168|hsa:2947|GSTM3, GST5, GSTB, GSTM3-3, GTM3; glutathione S-transferase mu 3 (brain) (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain"	Glutathione S-transferase Mu 3 GN=GSTM3 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase Mu 3 [Tupaia chinensis] 
ENSG00000134207(SYT6)	--	0.03690602	3	0.030476572	1	0	0	0.72272772	52	0.859032323	70	0.608977729	45	2.83E-08	3.535717836	up	2.54E-14	4.816379449	up	1.04E-09	4.938801562	up	3.28E-15	5.359960065	up	[R]	General function prediction only	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-6 GN=SYT6 OS=Homo sapiens (Human) PE=1 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-6 [Equus caballus]
ENSG00000134215(VAV3)	--	2.34980652	119	1.97437928	84	2.1564116	91	1.560606328	86	2.15512547	128	2.42123155	136	0.830795019	-0.491878756	normal	0.691273222	0.577773326	normal	0.692782605	0.56366555	normal	0.639651132	0.23161879	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Biological Process: intracellular signal transduction (GO:0035556);; 	K05730|0|mcf:101865181|uncharacterized LOC101865181; K05730 guanine nucleotide exchange factor VAV (A)	cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	RhoGEF domain;; Variant SH3 domain;; CAMSAP CH domain;; Variant SH3 domain;; SH3 domain;; SH2 domain;; Calponin homology (CH) domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; PH domain;; CDC24 Calponin	Guanine nucleotide exchange factor VAV3 GN=VAV3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide exchange factor VAV3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000134222(PSRC1)	--	7.353810259	272	7.608929585	279	8.948824834	329	9.061434221	330	9.230872306	305	9.717793092	346	0.929361869	0.246760144	normal	0.961549456	0.106564996	normal	0.966727696	0.06410565	normal	0.683251619	0.135985748	normal	--	--	--	--	--	--	--	G-2 and S-phase expressed 1	Proline/serine-rich coiled-coil protein 1 GN=PSRC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: proline/serine-rich coiled-coil protein 1 [Condylura cristata]
ENSG00000134242(PTPN22)	--	0	0	0	0	0.053838496	1	0	0	0.103646006	3	0.041018428	1	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18024|0|pps:100974686|PTPN22; protein tyrosine phosphatase, non-receptor type 22 (lymphoid); K18024 tyrosine-protein phosphatase non-receptor type 12/18/22 [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase	Tyrosine-protein phosphatase non-receptor type 22 GN=PTPN22 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 22 isoform X1 [Galeopterus variegatus]
ENSG00000134243(SORT1)	--	10.00203727	1237	11.85187636	1472	9.350819718	1120	13.79725915	1706	14.58767261	1793	19.36243583	2394	0.625619288	0.43248077	normal	0.945076962	0.262926176	normal	1.14E-08	1.086605551	up	0.033255756	0.601487356	normal	--	--	--	K12388|0|ptr:457090|SORT1; sortilin 1; K12388 sortilin (A)	Lysosome (ko04142);; Neurotrophin signaling pathway (ko04722)	[R]	General function prediction only	BNR/Asp-box repeat	Sortilin (Precursor) GN=SORT1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: sortilin isoform X1 [Orycteropus afer afer]
ENSG00000134245(WNT2B)	--	0.3047528	41	0.10941454	22	0.483997144	49	0.553364972	52	0.505845788	61	0.449396808	46	0.970060096	0.301988664	normal	0.032035499	1.390246598	normal	0.978542678	-0.096369076	normal	0.42303916	0.485056231	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00182|0|ggo:101129834|WNT2B; protein Wnt-2b; K00182 wingless-type MMTV integration site family, member 2 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-2b (Precursor) GN=WNT2B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-2b [Orcinus orca] 
ENSG00000134247(PTGFRN)	--	9.195121	1069	8.56473	1001	8.082579	948	14.43489	1664	14.52438	1667	12.57736	1456	0.051085217	0.606857078	normal	0.005004863	0.713541703	normal	0.049320077	0.609968932	normal	6.80E-06	0.643838888	normal	--	--	--	"K06729|0|hsa:5738|PTGFRN, CD315, CD9P-1, EWI-F, FPRP, SMAP-6; prostaglandin F2 receptor inhibitor; K06729 prostaglandin F2 receptor negative regulator (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Prostaglandin F2 receptor negative regulator (Precursor) GN=PTGFRN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: prostaglandin F2 receptor negative regulator [Galeopterus variegatus]
ENSG00000134248(LAMTOR5)	--	101.6727017	813	108.5929433	886	106.1361645	867	120.8845256	1002	107.635846	848	115.4424621	932	0.923722699	0.270262261	normal	0.974462757	-0.08452151	normal	0.974590253	0.095845245	normal	0.69997298	0.095140838	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: viral genome replication (GO:0019079);; Biological Process: negative regulation of apoptotic process (GO:0043066);; Biological Process: negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0043154);; Cellular Component: Ragulator complex (GO:0071986);; 	"K16344|1.50968e-123|hsa:10542|LAMTOR5, HBXIP, XIP; late endosomal/lysosomal adaptor, MAPK and MTOR activator 5; K16344 hepatitis B virus X-interacting protein (A)"	Hepatitis B (ko05161)	--	--	--	Ragulator complex protein LAMTOR5 GN=LAMTOR5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ragulator complex protein LAMTOR5 [Galeopterus variegatus]
ENSG00000134250(NOTCH2)	--	14.53202258	3228	12.92348623	2872	14.17545515	3112	23.83207364	5222	21.1306936	4614	18.34815602	4040	0.015445612	0.662879371	normal	0.019084508	0.662258157	normal	0.877261256	0.368064384	normal	0.000111079	0.56909845	normal	[R]	General function prediction only	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: cell differentiation (GO:0030154);; 	K02599|0|mcf:101864989|uncharacterized LOC101864989; K02599 Notch (A)	Dorso-ventral axis formation (ko04320);; Notch signaling pathway (ko04330);; Thyroid hormone signaling pathway (ko04919);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	EGF-like domain;; Calcium-binding EGF domain;; Human growth factor-like EGF;; Ankyrin repeat;; Ankyrin repeats (3 copies);; NOTCH protein;; Domain of unknown function (DUF3454);; Ankyrin repeats (many copies);; LNR domain;; NOTCH protein;; Ankyrin repeat;; EGF-like domain;; Ankyrin repeats (many copies)	Notch 2 intracellular domain (Precursor) GN=NOTCH2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neurogenic locus notch homolog protein 2 [Ceratotherium simum simum]
ENSG00000134253(TRIM45)	--	1.50974539	91	1.790519684	122	1.844407034	121	1.27582922	82	0.93207351	64	1.262568102	87	0.965798568	-0.177908639	normal	0.059881097	-0.935865217	normal	0.842852663	-0.477146232	normal	0.184064564	-0.54046273	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Cellular Component: intracellular (GO:0005622);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; Molecular Function: metal ion binding (GO:0046872);; 	K12021|0|pps:100975468|TRIM45; tripartite motif containing 45; K12021 tripartite motif-containing protein 45 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Filamin/ABP280 repeat;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 45 GN=TRIM45 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 45 [Panthera tigris altaica]
ENSG00000134255(CEPT1)	--	9.200411847	280	8.5784	261	8.195259895	246	9.1789028	282	8.16652	242	10.20858248	310	0.967341997	-0.020452103	normal	0.958559212	-0.12968869	normal	0.882751403	0.323542936	normal	0.883261986	0.062558312	normal	[I]	Lipid transport and metabolism	"Biological Process: phospholipid biosynthetic process (GO:0008654);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, for other substituted phosphate groups (GO:0016780);; "	K13644|0|ptr:457116|CEPT1; choline/ethanolamine phosphotransferase 1; K13644 choline/ethanolamine phosphotransferase [EC:2.7.8.1 2.7.8.2] (A)	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565)	[I]	Lipid transport and metabolism	CDP-alcohol phosphatidyltransferase	Choline/ethanolaminephosphotransferase 1 GN=CEPT1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: choline/ethanolaminephosphotransferase 1 isoform X1 [Oryctolagus cuniculus] 
ENSG00000134256(CD101)	--	0.05809734	4	0.100903093	7	0.114316067	7	0.05809106	4	0.112967508	7	0.130069267	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06522|0|hsa:9398|CD101, EWI-101, IGSF2, V7; CD101 molecule; K06522 immunoglobulin superfamily, member 2/3 (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	Immunoglobulin superfamily member 2 (Precursor) GN=CD101 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 2 isoform X1 [Galeopterus variegatus]
ENSG00000134258(VTCN1)	--	0	0	0	0	0	0	0.107290892	5	0.2697651	12	0.10600406	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06747|0|nle:100602199|VTCN1; V-set domain containing T cell activation inhibitor 1; K06747 immune costimulatory protein B7-H4 (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain	V-set domain-containing T-cell activation inhibitor 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: V-set domain-containing T-cell activation inhibitor 1 isoform X1 [Galeopterus variegatus]
ENSG00000134259(NGF)	--	0.632422	10	0.250334	4	0.0612643	0	0.557371	9	0.73464	11	0.186842	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; 	"K02582|1.25505e-163|hsa:4803|NGF, Beta-NGF, HSAN5, NGFB; nerve growth factor (beta polypeptide); K02582 nerve growth factor, beta (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Neurotrophin signaling pathway (ko04722);; Inflammatory mediator regulation of TRP channels (ko04750)	--	--	Nerve growth factor family	Beta-nerve growth factor (Precursor) GN=NGF OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: beta-nerve growth factor isoform X1 [Equus caballus] 
ENSG00000134262(AP4B1)	--	3.415660353	162	2.722755187	136	3.360499581	166	4.238856617	207	5.097826995	248	4.669185137	219	0.905208427	0.320113443	normal	0.014970994	0.838306509	normal	0.84440286	0.388366538	normal	0.073173205	0.517911939	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K12401|0|hsa:10717|AP4B1, BETA-4, CPSQ5, SPG47; adaptor-related protein complex 4, beta 1 subunit; K12401 AP-4 complex subunit beta-1 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Adaptin N terminal region;; Beta2-adaptin appendage, C-terminal sub-domain;; HEAT repeats;; non-SMC mitotic condensation complex subunit 1;; HEAT repeat"	AP-4 complex subunit beta-1 GN=AP4B1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-4 complex subunit beta-1 isoform X1 [Panthera tigris altaica] 
ENSG00000134265(NAPG)	--	8.176724	419	6.489124	337	8.605343	432	8.461038	415	8.580121	436	6.713021	349	0.96915743	-0.044507181	normal	0.842229473	0.348773664	normal	0.880127544	-0.314866958	normal	0.990396904	-0.00683451	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Soluble NSF attachment protein, SNAP"	Gamma-soluble NSF attachment protein GN=NAPG OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: gamma-soluble NSF attachment protein [Dasypus novemcinctus]
ENSG00000134278(SPIRE1)	--	7.955035748	791	9.394569	857	7.627174	752	7.25988963	724	7.77218068	767	9.907660615	991	0.963748963	-0.15819892	normal	0.959496229	-0.181157061	normal	0.747680621	0.38917712	normal	0.948073478	0.028037119	normal	--	--	--	"K02098|0|hsa:56907|SPIRE1, Spir-1; spire-type actin nucleation factor 1; K02098 spire (A)"	Dorso-ventral axis formation (ko04320)	--	--	--	Protein spire homolog 1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein spire homolog 1 [Oryctolagus cuniculus]
ENSG00000134283(PPHLN1)	--	23.16337115	981	26.1738505	1108	26.60376028	1069	32.797694	1282	37.60558206	1398	28.3469981	1187	0.831363275	0.354751718	normal	0.897963828	0.313598129	normal	0.972444506	0.142575153	normal	0.120712638	0.270873281	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: viral capsid (GO:0019028);; 	--	--	[R]	General function prediction only	Retroviral GAG p10 protein;; RNase H;; Reverse transcriptase (RNA-dependent DNA polymerase)	Integrase GN=ERVK-8 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: endogenous retrovirus group K member 11 Pol protein-like [Bison bison bison]
ENSG00000134285(FKBP11)	--	92.49409505	5231	86.86691043	5235	91.58058616	5434	102.7996698	6030	105.5160794	5855	82.36955705	4780	0.988766584	0.174191288	normal	0.990689975	0.140014816	normal	0.985962764	-0.193238007	normal	0.866895467	0.046030307	normal	--	--	--	"K09576|2.32502e-104|pon:100440375|FKBP11; FK506 binding protein 11, 19 kDa; K09576 FK506-binding protein 11 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase	Peptidyl-prolyl cis-trans isomerase FKBP11 (Precursor) GN=FKBP11 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP11 [Odobenus rosmarus divergens]
ENSG00000134291(TMEM106C)	--	74.7497866	1625	83.21517782	1666	81.863115	1666	93.182902	2032	80.96579525	1718	99.152589	2147	0.929798507	0.291381638	normal	0.984755295	0.022894613	normal	0.854080516	0.357355871	normal	0.191160967	0.229431058	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1356)	Transmembrane protein 106C GN=TMEM106C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 106C [Ursus maritimus] 
ENSG00000134294(SLC38A2)	--	151.60721	9414	219.59231	13770	188.72641	11354	108.62297	7061	117.74907	7360	213.2154	13321	0.773417022	-0.445683279	normal	7.64E-06	-0.925036098	normal	0.991003972	0.222182952	normal	0.557843429	-0.335498911	normal	[E]	Amino acid transport and metabolism	--	"K14207|0|hsa:54407|SLC38A2, ATA2, PRO1068, SAT2, SNAT2; solute carrier family 38, member 2; K14207 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 2 (A)"	Glutamatergic synapse (ko04724);; GABAergic synapse (ko04727);; Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Sodium-coupled neutral amino acid transporter 2 GN=SLC38A2 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: sodium-coupled neutral amino acid transporter 2 isoform X1 [Orycteropus afer afer]
ENSG00000134308(YWHAQ)	--	395.568574	13501	386.547032	13125	421.3116	14165	402.4233804	13884	367.9162115	12542	303.116145	10383	0.997131557	0.009523668	normal	0.996293961	-0.086966304	normal	0.789741807	-0.456341554	normal	0.444885155	-0.170114482	normal	--	--	--	"K16197|1.11117e-167|umr:103675032|YWHAQ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta; K16197 14-3-3 protein beta/theta/zeta (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; Hippo signaling pathway (ko04390);; Hepatitis B (ko05161);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein	14-3-3 protein theta GN=YWHAQ OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 14-3-3 protein theta [Erinaceus europaeus]
ENSG00000134313(KIDINS220)	--	14.40799874	2045	16.64685694	2334	16.06818821	2174	15.26850202	2178	14.41253535	2080	17.11548179	2402	0.98643551	0.060027145	normal	0.975425933	-0.187518798	normal	0.982852414	0.135503062	normal	0.998020245	0.002402811	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K12460|0|hsa:57498|KIDINS220, ARMS; kinase D-interacting substrate, 220kDa; K12460 ankyrin repeat-rich membrane spanning protein (A)"	Neurotrophin signaling pathway (ko04722)	[R]	General function prediction only	KAP family P-loop domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Kinase D-interacting substrate of 220 kDa GN=KIDINS220 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: kinase D-interacting substrate of 220 kDa isoformX1 [Canis lupus familiaris]
ENSG00000134317(GRHL1)	--	0.655748802	43	0.62799474	41	0.710759628	46	0.425680711	28	0.265505828	17	0.277406394	8	0.933877936	-0.621988285	normal	0.439413419	-1.21956711	normal	0.000266644	-2.327936845	down	0.015724671	-1.318948515	normal	--	--	--	"K09275|0|hsa:29841|GRHL1, LBP32, MGR, NH32, TFCP2L2; grainyhead-like 1 (Drosophila); K09275 transcription factor CP2 and related proteins (A)"	--	[K]	Transcription	CP2 transcription factor	Grainyhead-like protein 1 homolog GN=GRHL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: grainyhead-like protein 1 homolog [Trichechus manatus latirostris]
ENSG00000134318(ROCK2)	--	26.3825077	4221	33.31208919	5296	32.24076271	5075	23.1811867	3697	23.7684504	3728	24.13267408	3863	0.978412548	-0.221975631	normal	0.333907664	-0.527747204	normal	0.828552745	-0.401839895	normal	0.012355336	-0.391374327	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Molecular Function: Rho GTPase binding (GO:0017048);; 	"K17388|0|hsa:9475|ROCK2, ROCK-II; Rho-associated, coiled-coil containing protein kinase 2 (EC:2.7.11.1); K17388 Rho-associated protein kinase 2 [EC:2.7.11.1] (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Pathogenic Escherichia coli infection (ko05130);; Shigellosis (ko05131);; Salmonella infection (ko05132);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Protein kinase domain;; Rho Binding;; Protein tyrosine kinase;; Hr1 repeat;; PH domain	Rho-associated protein kinase 2 GN=ROCK2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: rho-associated protein kinase 2 [Galeopterus variegatus]
ENSG00000134321(RSAD2)	--	0	0	0.017769805	1	0	0	0	0	0	0	0.048573782	3	--	--	--	--	--	--	--	--	--	--	--	--	[H]	Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	"K15045|0|hsa:91543|RSAD2, 2510004L01Rik, cig33, cig5, vig1; radical S-adenosyl methionine domain containing 2; K15045 radical S-adenosyl methionine domain-containing protein 2 (A)"	Influenza A (ko05164)	--	--	Radical SAM superfamily;; 4Fe-4S single cluster domain;; 4Fe-4S single cluster domain	Radical S-adenosyl methionine domain-containing protein 2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: radical S-adenosyl methionine domain-containing protein 2 [Loxodonta africana]
ENSG00000134323(MYCN)	--	0.034596913	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09109|0|hsa:4613|MYCN, MODED, N-myc, NMYC, ODED, bHLHe37; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; K09109 N-myc proto-oncogene protein (A)"	Transcriptional misregulation in cancer (ko05202)	--	--	Myc amino-terminal region;; Helix-loop-helix DNA-binding domain	N-myc proto-oncogene protein GN=MYCN OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: N-myc proto-oncogene protein isoform X1 [Loxodonta africana] 
ENSG00000134324(LPIN1)	--	18.26354001	1892	23.23687241	2422	18.37453608	1916	8.373878299	875	8.972913252	904	17.04807345	1805	1.69E-09	-1.141989909	down	3.00E-15	-1.441695252	down	0.983612966	-0.094313457	normal	0.045065823	-0.816912029	normal	[R]	General function prediction only	--	K15728|0|ptr:459036|LPIN1; lipin 1; K15728 phosphatidate phosphatase LPIN [EC:3.1.3.4] (A)	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[NI]	Cell motility;; Lipid transport and metabolism	"LNS2 (Lipin/Ned1/Smp2);; lipin, N-terminal conserved region"	Phosphatidate phosphatase LPIN1 GN=LPIN1 OS=Homo sapiens (Human) PE=1 SV=2	IN	Lipid transport and metabolism;; Cell motility	PREDICTED: phosphatidate phosphatase LPIN1 isoform X1 [Tupaia chinensis]
ENSG00000134326(CMPK2)	--	0.246361114	8	0.577712016	22	0.083528655	3	0.0213351	1	0.103691997	4	0.106073	5	--	--	--	0.234427656	-2.110492538	normal	--	--	--	--	--	--	--	--	--	"K13809|0|ptr:459005|CMPK2; cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial; K13809 UMP-CMP kinase 2, mitochondrial [EC:2.7.4.14] (A)"	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Thymidylate kinase;; AAA domain;; AAA domain	"UMP-CMP kinase 2, mitochondrial (Precursor) GN=CMPK2 OS=Homo sapiens (Human) PE=1 SV=3"	F	Nucleotide transport and metabolism	"PREDICTED: UMP-CMP kinase 2, mitochondrial [Tupaia chinensis]"
ENSG00000134330(IAH1)	--	46.361273	807	43.822447	740	44.529826	784	30.950934	531	32.815609	590	31.76627	549	0.042098394	-0.633191003	normal	0.836255384	-0.34743978	normal	0.281042811	-0.521131149	normal	0.003317009	-0.50209969	normal	[E]	Amino acid transport and metabolism	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	--	--	[I]	Lipid transport and metabolism	GDSL-like Lipase/Acylhydrolase;; GDSL-like Lipase/Acylhydrolase family	Isoamyl acetate-hydrolyzing esterase 1 homolog GN=IAH1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: isoamyl acetate-hydrolyzing esterase 1 homolog [Ceratotherium simum simum]
ENSG00000134333(LDHA)	--	1338.362867	47571	1073.998332	38976	1248.303297	42867	1219.999612	44086	781.94163	27799	912.6129569	32600	0.998437781	-0.140589313	normal	0.763498476	-0.508956106	normal	0.961051789	-0.403270566	normal	0.250809028	-0.331016287	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00016|0|mcf:101867330|uncharacterized LOC101867330; K00016 L-lactate dehydrogenase [EC:1.1.1.27] (A)	Glycolysis / Gluconeogenesis (ko00010);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640)	[C]	Energy production and conversion	"lactate/malate dehydrogenase, NAD binding domain;; lactate/malate dehydrogenase, alpha/beta C-terminal domain"	L-lactate dehydrogenase A chain GN=LDHA OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	L-lactate dehydrogenase A chain [Pteropus alecto]
ENSG00000134339(SAA2)	--	0	0	0	0	0	0	1.594517091	12	1.682451086	14	3.509659048	31	--	--	--	--	--	--	4.36E-06	4.422232783	up	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; 	"K17310|2.88002e-66|ptr:748829|SAA2, SAA4; serum amyloid A2; K17310 serum amyloid A protein (A)"	--	--	--	Serum amyloid A protein	Serum amyloid A-2 protein (Precursor) GN=SAA2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: serum amyloid A-1 protein-like [Trichechus manatus latirostris]
ENSG00000134343(ANO3)	--	0.018765818	1	0	0	0	0	0.022113146	2	0.017551752	0	0.022081832	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[S]	Function unknown	Calcium-activated chloride channel	Anoctamin-3 GN=ANO3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: anoctamin-3 [Tupaia chinensis]
ENSG00000134352(IL6ST)	--	51.24469232	7126	47.3829524	6503	49.42135031	6712	38.58486186	5470	34.98308127	4723	45.20270098	6279	0.836810548	-0.412282112	normal	0.588465609	-0.482696117	normal	0.993282057	-0.104475003	normal	0.05379968	-0.325221424	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05060|0|ptr:461866|IL6ST; interleukin 6 signal transducer; K05060 interleukin 6 signal transducer (A)	Cytokine-cytokine receptor interaction (ko04060);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; Viral carcinogenesis (ko05203)	--	--	"Ig-like C2-type domain;; Fibronectin type III domain;; Interleukin-6 receptor alpha chain, binding;; Erythropoietin receptor, ligand binding;; Interferon-alpha/beta receptor, fibronectin type III"	Interleukin-6 receptor subunit beta (Precursor) GN=IL6ST OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-6 receptor subunit beta isoform X1 [Galeopterus variegatus]
ENSG00000134363(FST)	--	0.51785044	22	0.412276179	11	0.458363764	19	1.811662364	78	1.230047	52	3.3907481	125	0.000195986	1.727190338	up	0.000505988	2.076695979	up	8.10E-13	2.616780948	up	0.004719196	2.274519528	up	--	--	Molecular Function: protein binding (GO:0005515);; 	K04661|0|ptr:461879|FST; follistatin; K04661 follistatin (A)	TGF-beta signaling pathway (ko04350)	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Follistatin/Osteonectin-like EGF domain	Follistatin (Precursor) GN=FST OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: follistatin isoform X1 [Galeopterus variegatus]
ENSG00000134369(NAV1)	--	1.308273047	345	1.170086111	278	2.36952002	296	5.662965429	1180	5.891796245	1529	4.727098128	1049	0	1.738841169	up	0	2.431672997	up	0	1.811807473	up	2.72E-11	2.010444226	up	--	--	--	K16776|0|mcf:102141619|NAV1; neuron navigator 1; K16776 neuron navigator 1 (A)	--	--	--	--	Neuron navigator 1 GN=NAV1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: neuron navigator 1 isoform 1 [Trichechus manatus latirostris]
ENSG00000134371(CDC73)	--	16.40321345	1367	17.69084952	1485	17.10214284	1374	14.38109269	1241	15.33746077	1281	14.04786402	1170	0.970105796	-0.170141577	normal	0.953591281	-0.234361767	normal	0.949156274	-0.239878474	normal	0.236089793	-0.216304179	normal	--	--	--	K15175|0|ptr:745351|CDC73; cell division cycle 73; K15175 parafibromin (A)	--	[K]	Transcription	"RNA pol II accessory factor, Cdc73 family"	Parafibromin GN=CDC73 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: parafibromin [Condylura cristata] 
ENSG00000134375(TIMM17A)	--	51.6944	1203	54.6392	1275	58.8101	1354	53.1681	1263	54.5985	1268	52.9428	1241	0.981399556	0.039336701	normal	0.981572549	-0.02933417	normal	0.97562211	-0.133859843	normal	0.874611439	-0.043850287	normal	--	--	--	K17795|8.49619e-81|ptg:102972483|TIMM17A; translocase of inner mitochondrial membrane 17 homolog A (yeast); K17795 mitochondrial import inner membrane translocase subunit TIM17 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim17/Tim22/Tim23/Pmp24 family	Mitochondrial import inner membrane translocase subunit Tim17-A GN=TIMM17A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim17-A [Echinops telfairi]
ENSG00000134398(ERN2)	--	0	0	0.10436499	8	0.0434545	2	0	0	0.0292956	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: ribonuclease activity (GO:0004540);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: mRNA processing (GO:0006397);; Biological Process: protein phosphorylation (GO:0006468);; 	"K11715|0|hsa:10595|ERN2, IRE1-BETA, IRE1b; endoplasmic reticulum to nucleus signaling 2 (EC:2.7.11.1); K11715 serine/threonine-protein kinase/endoribonuclease IRE2 [EC:2.7.11.1 3.1.26.-] (A)"	--	[T]	Signal transduction mechanisms	Ribonuclease 2-5A;; Protein kinase domain;; Protein tyrosine kinase	Endoribonuclease (Precursor) OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase/endoribonuclease IRE2 [Trichechus manatus latirostris]
ENSG00000134419(RPS15A)	--	2004.044437	15688	1813.676175	14786	1756.241807	14342	1944.150554	17965	1946.880195	16095	1863.220058	16221	0.99570217	0.164680152	normal	0.996639177	0.100944303	normal	0.995134841	0.169308301	normal	0.542395782	0.144372722	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02957|3.46892e-91|cjc:100394618|RPS15A; ribosomal protein S15a; K02957 small subunit ribosomal protein S15Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S8	40S ribosomal protein S15a GN=RPS15A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	"40S ribosomal protein S15a, partial [Bos mutus]"
ENSG00000134438(RAX)	--	0	0	0	0	0	0	0.036467997	2	0.020024234	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09332|2.57563e-142|ptr:468552|RAX; retina and anterior neural fold homeobox; K09332 retina and anterior neural fold homeobox protein (A)	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Retinal homeobox protein Rx GN=RAX OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: retinal homeobox protein Rx [Ceratotherium simum simum]
ENSG00000134440(NARS)	--	63.07510113	3607	77.3972243	3935	65.07462542	3624	61.03624428	3461	61.1430667	3215	73.10469812	3888	0.98982137	-0.090403428	normal	0.941004132	-0.312838187	normal	0.990156911	0.0931163	normal	0.651760683	-0.100924459	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01893|0|hsa:4677|NARS, ASNRS, NARS1; asparaginyl-tRNA synthetase (EC:6.1.1.22); K01893 asparaginyl-tRNA synthetase [EC:6.1.1.22] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class II (D, K and N);; OB-fold nucleic acid binding domain"	"Asparagine--tRNA ligase, cytoplasmic GN=NARS OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: asparagine--tRNA ligase, cytoplasmic isoform X1 [Ailuropoda melanoleuca]"
ENSG00000134444(KIAA1468)	--	7.616928	724	7.964536561	739	7.286343117	688	9.801283	781	7.939499201	724	8.845211206	742	0.973596943	0.078340504	normal	0.97428188	-0.050905975	normal	0.971223921	0.100506406	normal	0.893723959	0.04151104	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	HEAT repeat;; HEAT repeats	LisH domain and HEAT repeat-containing protein KIAA1468 GN=KIAA1468 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: lisH domain and HEAT repeat-containing protein KIAA1468 homolog isoform X2 [Sus scrofa]
ENSG00000134452(FBXO18)	--	17.32521662	1266	16.3170499	1208	16.8782199	1248	19.068363	1401	19.743414	1444	18.166912	1338	0.977921919	0.115214338	normal	0.952025761	0.235753491	normal	0.979500603	0.092060982	normal	0.475726871	0.147189584	normal	[L]	"Replication, recombination and repair"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K10300|0|ggo:101129472|FBXO18; F-box only protein 18; K10300 F-box protein, helicase, 18 [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	UvrD/REP helicase N-terminal domain;; UvrD-like helicase C-terminal domain;; UvrD-like helicase C-terminal domain;; F-box-like;; F-box domain;; Viral (Superfamily 1) RNA helicase	F-box only protein 18 GN=FBXO18 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: F-box only protein 18 [Equus caballus]
ENSG00000134453(RBM17)	--	28.59601147	1264	28.92421363	1373	36.67167407	1482	33.8883085	1480	36.1846144	1545	32.77129488	1332	0.965197212	0.196547495	normal	0.97502894	0.148694197	normal	0.972825043	-0.162068272	normal	0.815579992	0.059789116	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12840|0|pps:100994906|RBM17; RNA binding motif protein 17; K12840 splicing factor 45 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"G-patch domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing factor 45 GN=RBM17 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: splicing factor 45 [Elephantulus edwardii]
ENSG00000134461(ANKRD16)	--	6.613891723	314	5.1529615	280	7.382151442	320	5.868471247	247	5.957308	272	4.232968554	204	0.823111939	-0.375011083	normal	0.964760834	-0.06290202	normal	0.115572462	-0.653890653	normal	0.17161844	-0.359673771	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 16 GN=ANKRD16 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: uncharacterized protein LOC101343099 [Trichechus manatus latirostris]
ENSG00000134463(ECHDC3)	--	7.33723707	185	5.559333444	152	6.880558987	184	5.74521564	150	6.229036545	165	5.201141223	126	0.904290581	-0.330341644	normal	0.963185296	0.096050782	normal	0.596505676	-0.549086946	normal	0.499215526	-0.261897169	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	--	--	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family	"Enoyl-CoA hydratase domain-containing protein 3, mitochondrial (Precursor) GN=ECHDC3 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: enoyl-CoA hydratase domain-containing protein 3, mitochondrial [Chrysochloris asiatica]"
ENSG00000134470(IL15RA)	--	0.710672121	15	0.687812941	17	1.138391742	20	2.273723338	67	2.546080263	63	1.391259574	38	5.34E-05	2.022166262	up	0.000887916	1.780790635	up	0.868092851	0.869299086	normal	0.00070042	1.669592181	up	--	--	--	"K05074|5.01656e-150|hsa:3601|IL15RA, CD215; interleukin 15 receptor, alpha; K05074 interleukin 15 receptor alpha (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Intestinal immune network for IgA production (ko04672);; HTLV-I infection (ko05166)	--	--	--	Soluble interleukin-15 receptor subunit alpha (Precursor) GN=IL15RA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-15 receptor subunit alpha isoform X1 [Tupaia chinensis]
ENSG00000134480(CCNH)	--	24.97778284	553	20.74792312	460	20.97497153	453	21.49617813	476	21.39103614	453	17.42438238	383	0.929092731	-0.246411374	normal	0.969288604	-0.043405569	normal	0.926805013	-0.249550938	normal	0.484059674	-0.182081085	normal	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	--	K06634|0|ptr:739351|CCNH; cyclin H; K06634 cyclin H (A)	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420);; Cell cycle (ko04110)	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	"Cyclin, N-terminal domain"	Cyclin-H GN=CCNH OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-H [Pteropus alecto] 
ENSG00000134490(TMEM241)	--	3.574072804	169	6.619192701	190	4.889055824	191	4.040516419	160	3.882495059	156	2.374058868	115	0.963376216	-0.108767124	normal	0.915557614	-0.303211682	normal	0.134424979	-0.732673482	normal	0.274663114	-0.373733355	normal	--	--	--	--	--	[GOU]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	--	Transmembrane protein 241 GN=TMEM241 OS=Homo sapiens (Human) PE=2 SV=1	GOU	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane protein 241 [Equus caballus]
ENSG00000134504(KCTD1)	--	19.75357549	885	18.35002003	808	18.24985201	885	17.97076	831	16.11685	764	12.9455593	629	0.971234652	-0.121443605	normal	0.971695534	-0.102012824	normal	0.348870763	-0.499890567	normal	0.233395144	-0.234991033	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD1 GN=KCTD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000134508(CABLES1)	--	7.3397881	501	6.838694	463	5.9598005	429	6.07724193	407	8.146657543	420	7.230906328	489	0.86060051	-0.329490574	normal	0.955925629	-0.161495315	normal	0.952882793	0.179970764	normal	0.731290332	-0.102868118	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	CDK5 and ABL1 enzyme substrate 1 GN=CABLES1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: CDK5 and ABL1 enzyme substrate 1 [Equus caballus]
ENSG00000134516(DOCK2)	--	0.167077363	14	0.313037532	18	0.225643611	13	1.89411551	190	2.012338094	211	1.110915837	87	0	3.594704339	up	0	3.424571485	up	2.16E-09	2.600814181	up	1.93E-05	3.415571896	up	--	--	--	K12367|0|hsa:1794|DOCK2; dedicator of cytokinesis 2; K12367 dedicator of cytokinesis protein 2 (A)	Chemokine signaling pathway (ko04062);; Fc gamma R-mediated phagocytosis (ko04666)	[T]	Signal transduction mechanisms	C2 domain in Dock180 and Zizimin proteins;; Dedicator of cytokinesis;; Variant SH3 domain	Dedicator of cytokinesis protein 2 GN=DOCK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 2 [Canis lupus familiaris]
ENSG00000134531(EMP1)	--	2.948631846	189	6.199071687	162	2.518951832	168	5.697523936	303	5.678549601	250	3.117073803	214	0.146086114	0.645917642	normal	0.330787233	0.599966764	normal	0.89115709	0.338154906	normal	0.042503815	0.541182034	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Epithelial membrane protein 1 GN=EMP1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: epithelial membrane protein 1 [Canis lupus familiaris]
ENSG00000134533(RERG)	--	0.716494814	24	0.631185981	22	0.8154457	30	0.94397777	36	1.22651952	46	1.644140501	63	0.964629163	0.526460119	normal	0.660110409	0.994489295	normal	0.330950923	1.025664169	normal	0.09739485	0.912978039	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07855|1.27479e-145|pon:100433565|RERG; RAS-like, estrogen-regulated, growth inhibitor; K07855 Ras-related and estrogen-regulated growth inhibitor (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Ras-related and estrogen-regulated growth inhibitor GN=RERG OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related and estrogen-regulated growth inhibitor isoform 2 [Dasypus novemcinctus]
ENSG00000134538(SLCO1B1)	--	0.162827135	5	0.097821572	3	0.360103	11	0.582357	22	0.76843	25	0.835561229	33	0.519431993	1.822114655	normal	0.029251932	2.537508905	normal	0.395849046	1.456155813	normal	0.001499562	2.056074969	up	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K05043|0|hsa:10599|SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6; solute carrier organic anion transporter family, member 1B1; K05043 solute carrier organic anion transporter family, member 1B (A)"	Bile secretion (ko04976)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain	Solute carrier organic anion transporter family member 1B1 GN=SLCO1B1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 1B3-like [Galeopterus variegatus]
ENSG00000134539(KLRD1)	--	0	0	0	0	0	0	0	0	0	0	0.105844085	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06516|6.96102e-129|hsa:3824|KLRD1, CD94; killer cell lectin-like receptor subfamily D, member 1; K06516 killer cell lectin-like receptor subfamily D member 1 (A)"	Antigen processing and presentation (ko04612);; Natural killer cell mediated cytotoxicity (ko04650);; Graft-versus-host disease (ko05332)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	Natural killer cells antigen CD94 GN=KLRD1 OS=Homo sapiens (Human) PE=1 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: natural killer cells antigen CD94 [Ceratotherium simum simum]
ENSG00000134545(KLRC1)	--	2.906089514	41	1.902093022	31	1.77064186	24	2.842299061	41	3.306824952	49	4.5782112	68	0.981526369	-0.029718599	normal	0.917535705	0.615041815	normal	0.010026438	1.438120235	normal	0.209530558	0.698541963	normal	--	--	--	"K06541|2.8464e-148|hsa:3821|KLRC1, CD159A, NKG2, NKG2A; killer cell lectin-like receptor subfamily C, member 1; K06541 killer cell lectin-like receptor subfamily C (A)"	Antigen processing and presentation (ko04612);; Natural killer cell mediated cytotoxicity (ko04650);; Graft-versus-host disease (ko05332)	--	--	Lectin C-type domain;; UL45 protein	NKG2-A/NKG2-B type II integral membrane protein GN=KLRC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: NKG2-A/NKG2-B type II integral membrane protein-like [Equus caballus]
ENSG00000134548(SPX)	--	2.20843	71	0.911594	29	1.8771	59	1.86711	61	2.31433	75	3	98	0.965711124	-0.244135713	normal	0.018486651	1.305617286	normal	0.576837996	0.709521713	normal	0.35428838	0.538187497	normal	--	--	Molecular Function: neuropeptide hormone activity (GO:0005184);; 	--	--	--	--	"Neuropeptide secretory protein family, NPQ, spexin"	Spexin-2 (Precursor) GN=SPX OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: spexin [Tursiops truncatus]
ENSG00000134569(LRP4)	--	5.103574	914	3.952227	717	4.339385727	786	5.029122	896	5.850504057	1037	4.362056381	780	0.976997569	-0.059426797	normal	0.321696188	0.510045142	normal	0.976632638	-0.019309336	normal	0.598083532	0.145190354	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor repeat class B;; Low-density lipoprotein receptor domain class A;; Coagulation Factor Xa inhibitory site;; SMP-30/Gluconolaconase/LRE-like region;; Complement Clr-like EGF-like;; Calcium-binding EGF domain	Low-density lipoprotein receptor-related protein 4 (Precursor) GN=LRP4 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 4 [Camelus bactrianus]
ENSG00000134571(MYBPC3)	--	0.05279781	5	0.04120061	4	0.06044555	5	0.02103579	2	0.01025664	0	0.01045055	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12568|0|hsa:4607|MYBPC3, CMD1MM, CMH4, FHC, LVNC10, MYBP-C; myosin binding protein C, cardiac; K12568 myosin-binding protein C, cardiac-type (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	--	--	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain;; Alphaherpesvirus glycoprotein I	"Myosin-binding protein C, cardiac-type GN=MYBPC3 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: myosin-binding protein C, cardiac-type [Mustela putorius furo]"
ENSG00000134574(DDB2)	--	37.32477003	1313	39.81922123	1420	38.79668995	1396	37.05315506	1356	38.4108469	1392	44.68045792	1617	0.982718748	0.01563999	normal	0.982164599	-0.05010438	normal	0.965300339	0.203524268	normal	0.818502798	0.059542395	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10140|0|ptr:451165|DDB2; damage-specific DNA binding protein 2, 48kDa; K10140 DNA damage-binding protein 2 (A)"	Nucleotide excision repair (ko03420);; p53 signaling pathway (ko04115);; Ubiquitin mediated proteolysis (ko04120);; Hepatitis B (ko05161)	[S]	Function unknown	"WD domain, G-beta repeat"	DNA damage-binding protein 2 GN=DDB2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DNA damage-binding protein 2 [Ceratotherium simum simum]
ENSG00000134575(ACP2)	--	14.74740077	577	11.64510001	464	12.085245	482	17.97865842	707	20.225473	781	18.0827848	711	0.922798775	0.261676308	normal	0.00712903	0.727923104	normal	0.198015663	0.551092663	normal	0.003586665	0.508723655	normal	--	--	Molecular Function: acid phosphatase activity (GO:0003993);; 	"K14410|0|pon:100174154|ACP2, LAP; acid phosphatase 2, lysosomal (EC:3.1.3.2); K14410 acid phosphatase [EC:3.1.3.2] (A)"	Riboflavin metabolism (ko00740)	[I]	Lipid transport and metabolism	Histidine phosphatase superfamily (branch 2)	Lysosomal acid phosphatase (Precursor) GN=ACP2 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: lysosomal acid phosphatase [Ursus maritimus]
ENSG00000134590(FAM127A)	--	92.0656	1506	91.8083	1509	97.9326	1645	115.789	1926	98.4542	1609	102.162	1701	0.896647229	0.323760987	normal	0.982494372	0.071075975	normal	0.984721735	0.03996798	normal	0.468246626	0.146656302	normal	--	--	--	--	--	--	--	--	Protein FAM127A GN=FAM127A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM127A [Galeopterus variegatus]
ENSG00000134594(RAB33A)	--	0.532369	12	0.344255	8	0.336924	7	0.043228	1	0.128549	2	0.173707	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07919|4.82572e-178|hsa:9363|RAB33A, RabS10; RAB33A, member RAS oncogene family; K07919 Ras-related protein Rab-33A (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase;; Signal recognition particle receptor beta subunit;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-33A GN=RAB33A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-33A [Equus przewalskii]
ENSG00000134597(RBMX2)	--	14.53112537	549	15.72052475	565	15.32105624	561	14.98343898	563	14.79389023	536	15.89636476	576	0.972817012	0.005481362	normal	0.96769439	-0.097177331	normal	0.972792255	0.029697591	normal	0.957636091	-0.021136481	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13107|4.43945e-152|hsa:51634|RBMX2, CGI-79; RNA binding motif protein, X-linked 2; K13107 RNA-binding motif protein, X-linked 2 (A)"	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"RNA-binding motif protein, X-linked 2 GN=RBMX2 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: RNA-binding motif protein, X-linked 2 [Orcinus orca]"
ENSG00000134602(STK26)	--	12.69413745	626	12.7203105	631	12.59018384	610	11.00476598	553	9.89016187	487	8.213591895	412	0.946630282	-0.209168765	normal	0.746614356	-0.394066433	normal	0.159928553	-0.572717315	normal	0.0470826	-0.384805715	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08838|0|mcf:102127894|serine/threonine-protein kinase MST4-like; K08838 serine/threonine-protein kinase 24/25/MST4 [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 26 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase MST4-like isoform 1 [Odobenus rosmarus divergens] 
ENSG00000134627(PIWIL4)	--	0.082054272	5	0	0	0.032906521	1	0.016499859	1	0.176565097	10	0.21677212	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	"K02156|0|hsa:143689|PIWIL4, HIWI2, MIWI2; piwi-like RNA-mediated gene silencing 4; K02156 aubergine (A)"	Dorso-ventral axis formation (ko04320)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Piwi domain;; PAZ domain	Piwi-like protein 4 GN=PIWIL4 OS=Homo sapiens (Human) PE=2 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: piwi-like protein 4 [Ceratotherium simum simum]
ENSG00000134644(PUM1)	--	20.47531908	1898	21.22663014	1983	20.97869031	1970	23.33077951	2265	25.49344955	2340	23.30665528	2248	0.966015214	0.224032619	normal	0.968728828	0.217244639	normal	0.975817774	0.18202407	normal	0.249932624	0.206881275	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; 	K17943|0|mcc:704848|PUM1; pumilio homolog 1 (Drosophila); K17943 pumilio RNA-binding family (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Pumilio-family RNA binding repeat	Pumilio homolog 1 GN=PUM1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: pumilio homolog 1 isoform X1 [Sorex araneus]
ENSG00000134668(SPOCD1)	--	1.853588813	88	1.254696076	66	2.440433499	113	9.281128483	413	6.204109082	298	3.260751748	167	0	2.180440996	up	2.22E-16	2.128260668	up	0.639209891	0.54915189	normal	0.015400431	1.694415634	normal	--	--	"Biological Process: transcription, DNA-templated (GO:0006351);; "	"K17596|0|hsa:90853|SPOCD1, PPP1R146; SPOC domain containing 1; K17596 SPOC domain-containing protein 1 (A)"	--	[K]	Transcription	"Transcription factor S-II (TFIIS), central domain;; SPOC domain"	SPOC domain-containing protein 1 GN=SPOCD1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: SPOC domain-containing protein 1 [Galeopterus variegatus]
ENSG00000134684(YARS)	--	52.02316	2754	50.68964	2842	55.91537	2878	40.79739	2176	37.36929	2017	54.17259	2965	0.846350442	-0.370449129	normal	0.321956788	-0.515794503	normal	0.989785232	0.034656129	normal	0.283500181	-0.263732341	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: tRNA binding (GO:0000049);; Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01866|0|hsa:8565|YARS, CMTDIC, TYRRS, YRS, YTS; tyrosyl-tRNA synthetase (EC:6.1.1.1); K01866 tyrosyl-tRNA synthetase [EC:6.1.1.1] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class I (W and Y);; Putative tRNA binding domain	"Tyrosine--tRNA ligase, cytoplasmic, N-terminally processed GN=YARS OS=Homo sapiens (Human) PE=1 SV=4"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tyrosine--tRNA ligase, cytoplasmic isoform X1 [Oryctolagus cuniculus]"
ENSG00000134686(PHC2)	--	22.24634636	1108	19.71329764	990	22.13652804	1130	29.39374908	1458	29.60390832	1458	26.19321046	1302	0.817382901	0.36475848	normal	0.21859538	0.536384682	normal	0.963234816	0.195870839	normal	0.02274069	0.36458025	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K11457|0|pps:100986640|PHC2; polyhomeotic homolog 2 (Drosophila); K11457 polyhomeotic-like protein 2 (A)	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Polyhomeotic-like protein 2 GN=PHC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: polyhomeotic-like protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000134690(CDCA8)	--	14.9056	709	13.50894	650	16.95712	806	17.44052	833	17.21362	818	13.90455	664	0.953247043	0.201295847	normal	0.886798311	0.30959127	normal	0.906634341	-0.287293167	normal	0.784353301	0.075167005	normal	--	--	--	"K11514|0|pon:100174395|CDCA8, Borealin; cell division cycle associated 8; K11514 Borealin (A)"	--	--	--	Cell division cycle-associated protein 8;; Nbl1 / Borealin N terminal	Borealin GN=CDCA8 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: borealin [Equus przewalskii]
ENSG00000134697(GNL2)	--	15.538794	767	17.073734	849	16.11286	790	14.99359908	754	15.6926443	778	14.73261911	735	0.975082453	-0.055382421	normal	0.966384295	-0.147147039	normal	0.970836835	-0.112177161	normal	0.666965354	-0.107153208	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K14537|0|hsa:29889|GNL2, HUMAUANTIG, NGP1, Ngp-1; guanine nucleotide binding protein-like 2 (nucleolar); K14537 nuclear GTP-binding protein (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	NGP1NT (NUC091) domain;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B	Nucleolar GTP-binding protein 2 GN=GNL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: nucleolar GTP-binding protein 2 [Equus caballus]
ENSG00000134698(AGO4)	--	2.286285369	272	2.336089758	284	2.2743911	270	2.396244	280	1.80187444	212	2.779593759	320	0.96739786	0.010927079	normal	0.723879461	-0.440527667	normal	0.9343228	0.235607534	normal	0.914921183	-0.045618055	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	"K11593|0|ptr:469278|AGO4, EIF2C4; argonaute RISC catalytic component 4; K11593 eukaryotic translation initiation factor 2C (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Piwi domain;; PAZ domain;; Domain of unknown function (DUF1785)	Protein argonaute-4 {ECO:0000255|HAMAP-Rule:MF_03033} GN=AGO4 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: protein argonaute-4 [Odobenus rosmarus divergens] 
ENSG00000134709(HOOK1)	--	2.378596117	237	2.29666071	228	2.74765763	269	1.419888	142	1.530044702	150	1.221374	121	0.04765362	-0.763360431	normal	0.305404815	-0.620385625	normal	1.99E-05	-1.150984759	down	0.000946239	-0.850947395	normal	--	--	--	"K16612|0|hsa:51361|HOOK1, HK1; hook microtubule-tethering protein 1; K16612 protein HOOK1 (A)"	--	--	--	HOOK protein	Protein Hook homolog 1 GN=HOOK1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein Hook homolog 1 [Orcinus orca] 
ENSG00000134716(CYP2J2)	--	0.396172	14	0.542998	19	0.448529	15	0.113155	4	0.0550099	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07418|0|hsa:1573|CYP2J2, CPJ2; cytochrome P450, family 2, subfamily J, polypeptide 2 (EC:1.14.14.1); K07418 cytochrome P450, family 2, subfamily J [EC:1.14.14.1] (A)"	Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; Serotonergic synapse (ko04726);; Inflammatory mediator regulation of TRP channels (ko04750);; Ovarian steroidogenesis (ko04913)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2J2 GN=CYP2J2 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2J2 [Galeopterus variegatus]
ENSG00000134717(BTF3L4)	--	31.008061	796	28.74311	749	32.180061	818	31.99200003	775	32.2177216	831	31.78022094	807	0.974730588	-0.069268873	normal	0.968759594	0.128210363	normal	0.97690478	-0.027771919	normal	0.984371613	0.00928593	normal	--	--	--	K01527|5.74811e-87|gga:424638|BTF3L4; basic transcription factor 3-like 4; K01527 nascent polypeptide-associated complex subunit beta (A)	--	[K]	Transcription	NAC domain	Transcription factor BTF3 homolog 4 GN=BTF3L4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor BTF3 homolog 4 [Galeopterus variegatus]
ENSG00000134744(ZCCHC11)	--	10.19132941	1030	12.00637608	1085	11.14836678	1002	7.435531	771	11.07525625	787	10.77067103	896	0.549777419	-0.44789852	normal	0.423086169	-0.483890447	normal	0.965131384	-0.169332895	normal	0.029586799	-0.365875615	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K13291|0|hsa:23318|ZCCHC11, PAPD3, TUT4; zinc finger, CCHC domain containing 11 (EC:2.7.7.52); K13291 terminal uridylyltransferase [EC:2.7.7.52] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cid1 family poly A polymerase;; Zinc knuckle;; Nucleotidyltransferase domain	Terminal uridylyltransferase 4 GN=ZCCHC11 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: terminal uridylyltransferase 4 isoform X3 [Galeopterus variegatus]
ENSG00000134748(PRPF38A)	--	4.04754	416	4.23837	435	4.68897	475	4.72417	489	5.2519	539	4.27506	441	0.94639933	0.201730929	normal	0.903134662	0.28694568	normal	0.964583597	-0.115060017	normal	0.654762812	0.126536138	normal	--	--	--	K12849|2.42369e-143|ptg:102955085|PRPF38A; pre-mRNA processing factor 38A; K12849 pre-mRNA-splicing factor 38A (A)	Spliceosome (ko03040)	[S]	Function unknown	PRP38 family;; Pre-mRNA-splicing factor 38-associated hydrophilic C-term	Pre-mRNA-splicing factor 38A GN=PRPF38A OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	hypothetical protein PANDA_003790 [Ailuropoda melanoleuca]
ENSG00000134755(DSC2)	--	2.324682568	209	2.649196193	256	2.284755366	205	3.147295	323	3.97776312	387	2.514381	248	0.246918953	0.593663646	normal	0.265276331	0.571997007	normal	0.926302738	0.264647282	normal	0.11726806	0.493855934	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K07601|0|pps:100995156|DSC2; desmocollin 2; K07601 desmocollin 2 (A)	Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin prodomain like	Desmocollin-2 (Precursor) GN=DSC2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: desmocollin-2 isoform 1 [Ceratotherium simum simum]
ENSG00000134757(DSG3)	--	0.0203332	2	0	0	0	0	0	0	0	0	0.0100811	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K07598|0|hsa:1830|DSG3, CDHF6, PVA; desmoglein 3; K07598 desmoglein 3 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Desmoglein-3 (Precursor) GN=DSG3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: desmoglein-3 [Odobenus rosmarus divergens]
ENSG00000134758(RNF138)	--	11.1797	279	6.153087	247	6.758857	268	9.151404	348	8.387447	315	6.301742	266	0.907184399	0.286574577	normal	0.878106783	0.327634141	normal	0.967246017	-0.018990633	normal	0.501092842	0.204617739	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10668|0|pon:100461071|RNF138; ring finger protein 138, E3 ubiquitin protein ligase; K10668 E3 ubiquitin-protein ligase RNF138 [EC:6.3.2.19] (A)"	--	--	--	"Drought induced 19 protein (Di19), zinc-binding;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain;; RING-type zinc-finger;; Zinc finger, C3HC4 type (RING finger);; MIZ/SP-RING zinc finger;; Zinc-finger of the MIZ type in Nse subunit"	E3 ubiquitin-protein ligase RNF138 GN=RNF138 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF138 isoformX1 [Sus scrofa] 
ENSG00000134759(ELP2)	--	13.19013943	768	15.31855849	864	14.82559701	749	18.3231341	1008	14.67556387	881	17.96953248	931	0.811892582	0.360853397	normal	0.977445809	0.006672583	normal	0.892805226	0.304970678	normal	0.253230572	0.222469339	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11374|0|hsa:55250|ELP2, SHINC-2, STATIP1, StIP; elongator acetyltransferase complex subunit 2; K11374 elongator complex protein 2 (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	"WD domain, G-beta repeat"	Elongator complex protein 2 GN=ELP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: elongator complex protein 2 isoform X4 [Physeter catodon]
ENSG00000134762(DSC3)	--	2.031221	209	2.010537048	245	1.9247065	217	2.368782	251	2.4397947	291	2.709978	314	0.938380081	0.231795604	normal	0.937573101	0.225532218	normal	0.475025692	0.521738902	normal	0.236846741	0.330688976	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K07602|0|hsa:1825|DSC3, CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP; desmocollin 3; K07602 desmocollin 3 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin prodomain like	Desmocollin-3 (Precursor) GN=DSC3 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: desmocollin-3 [Felis catus]
ENSG00000134769(DTNA)	--	0.384490205	19	0.471354399	28	0.864306099	20	0.422938133	17	0.055043307	2	0.143845043	6	--	--	--	0.001069547	-3.087104043	down	0.800331012	-1.52500227	normal	--	--	--	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[Z]	Cytoskeleton	"EF hand;; EF-hand;; Zinc finger, ZZ type"	Dystrobrevin alpha GN=DTNA OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: dystrobrevin alpha isoform X2 [Elephantulus edwardii]
ENSG00000134775(FHOD3)	--	6.890522541	780	5.4466064	635	6.993016054	796	9.090694	1039	12.9887205	1474	8.071213	925	0.765304197	0.38216323	normal	1.06E-09	1.191565537	up	0.953188571	0.208026548	normal	0.087054037	0.615851883	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain	FH1/FH2 domain-containing protein 3 GN=FHOD3 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: FH1/FH2 domain-containing protein 3 [Erinaceus europaeus]
ENSG00000134779(TPGS2)	--	51.49490103	1595	55.238622	1642	54.11280736	1566	60.63661209	1960	54.14022864	1759	56.95589396	1822	0.944964562	0.266233296	normal	0.983145837	0.077805556	normal	0.965873698	0.209959165	normal	0.324778138	0.184697255	normal	--	--	--	K16605|0|mcf:102116965|TPGS2; tubulin polyglutamylase complex subunit 2; K16605 tubulin polyglutamylase complex subunit 2 (A)	--	--	--	--	Tubulin polyglutamylase complex subunit 2 GN=TPGS2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: tubulin polyglutamylase complex subunit 2 isoform X4 [Equus caballus]
ENSG00000134780(DAGLA)	--	2.6954308	299	3.314026825	374	3.119328257	355	2.82401166	312	2.601931	286	2.996877508	335	0.967495864	0.030415282	normal	0.755379667	-0.406563563	normal	0.964857044	-0.091547842	normal	0.601492541	-0.160859216	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K13806|0|pps:100979217|DAGLA; diacylglycerol lipase, alpha; K13806 sn1-specific diacylglycerol lipase [EC:3.1.1.-] (A)"	Retrograde endocannabinoid signaling (ko04723)	[IOT]	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Lipase (class 3)	Sn1-specific diacylglycerol lipase alpha GN=DAGLA OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: sn1-specific diacylglycerol lipase alpha [Galeopterus variegatus]
ENSG00000134802(SLC43A3)	--	0.226127583	2	0.174495908	4	0	0	0.373367949	5	0.104435633	3	0.240328084	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Solute carrier family 43 member 3 GN=SLC43A3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: UPF0764 protein C16orf89-like [Camelus ferus]
ENSG00000134809(TIMM10)	--	73.31696699	593	71.82321423	600	80.41654882	670	84.319864	712	83.61553622	666	77.15784954	628	0.938704636	0.232462626	normal	0.965660395	0.128824832	normal	0.969936401	-0.101451407	normal	0.758315786	0.085331952	normal	--	--	--	K17778|8.77052e-60|tup:102486808|TIMM10; translocase of inner mitochondrial membrane 10 homolog (yeast); K17778 mitochondrial import inner membrane translocase subunit TIM10 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim10/DDP family zinc finger	Mitochondrial import inner membrane translocase subunit Tim10 GN=TIMM10 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim10 [Sorex araneus]
ENSG00000134815(DHX34)	--	13.39796	1232	15.1457	1400	14.833257	1381	11.14271	1021	10.624995	962	14.84969	1365	0.904116075	-0.301437967	normal	0.143498298	-0.562007605	normal	0.982948015	-0.02507619	normal	0.231945514	-0.28166701	normal	[L]	"Replication, recombination and repair"	Molecular Function: helicase activity (GO:0004386);; 	--	--	[A]	RNA processing and modification	Helicase associated domain (HA2);; Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase	Probable ATP-dependent RNA helicase DHX34 GN=DHX34 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DHX34 [Galeopterus variegatus]
ENSG00000134817(APLNR)	--	0	0	0	0	0	0	0.1076887	5	0.049584786	2	0.0167512	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K04174|0|hsa:187|APLNR, AGTRL1, APJ, APJR, HG11; apelin receptor; K04174 apelin receptor (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv;; Mammalian taste receptor protein (TAS2R)	Apelin receptor GN=APLNR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: apelin receptor [Odobenus rosmarus divergens]
ENSG00000134824(FADS2)	--	402.624515	18804	493.325647	22754	462.892897	21772	254.705821	12396	258.697761	12117	525.417757	24509	0.073278953	-0.631933087	normal	8.42E-06	-0.930427975	normal	0.996720925	0.162535592	normal	0.470429339	-0.388528846	normal	[CI]	Energy production and conversion;; Lipid transport and metabolism	Biological Process: lipid metabolic process (GO:0006629);; 	K10226|0|pps:100980611|FADS2; fatty acid desaturase 2; K10226 fatty acid desaturase 2 (delta-6 desaturase) [EC:1.14.19.-] (A)	alpha-Linolenic acid metabolism (ko00592);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	Fatty acid desaturase;; Cytochrome b5-like Heme/Steroid binding domain	Fatty acid desaturase 2 GN=FADS2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: fatty acid desaturase 2 isoform X2 [Mustela putorius furo]
ENSG00000134825(TMEM258)	--	115.075632	525	104.299	477	101.441153	463	142.93617	668	135.225702	614	124.826936	574	0.875324259	0.315877272	normal	0.844651514	0.341865306	normal	0.89101908	0.300862919	normal	0.116258856	0.319522889	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised protein family (UPF0197)	Transmembrane protein 258 GN=TMEM258 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	transmembrane protein 258 [Bos taurus] 
ENSG00000134827(TCN1)	--	0.116635223	3	0.274338323	7	0.3226088	7	0.855678	20	1.4944	38	1.422636126	37	--	--	--	0.004578851	2.195570189	up	0.006473122	2.170307942	up	--	--	--	--	--	Biological Process: cobalamin transport (GO:0015889);; Molecular Function: cobalamin binding (GO:0031419);; 	--	--	--	--	Eukaryotic cobalamin-binding protein;; Domain of unknown function (DUF4430)	Transcobalamin-1 (Precursor) GN=TCN1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: transcobalamin-1 [Tupaia chinensis]
ENSG00000134830(C5AR2)	--	0	0	0.016813222	2	0.176043011	2	0.125677832	3	0.016576536	1	0.080323397	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04171|0|hsa:27202|C5AR2, C5L2, GPF77, GPR77; complement component 5a receptor 2; K04171 G protein-coupled receptor 77 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	C5a anaphylatoxin chemotactic receptor 2 GN=C5AR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: C5a anaphylatoxin chemotactic receptor 2 [Lipotes vexillifer]
ENSG00000134851(TMEM165)	--	41.80585373	1055	43.639704	1135	36.37159317	929	58.05009865	1500	50.56076706	1289	53.88375	1375	0.433663476	0.476302874	normal	0.970114081	0.161930847	normal	0.141671291	0.556640232	normal	0.012018776	0.395071628	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Uncharacterized protein family UPF0016	Transmembrane protein 165 (Precursor) GN=TMEM165 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 165 [Orcinus orca] 
ENSG00000134852(CLOCK)	--	3.79002539	632	4.790359577	764	4.75583071	708	3.66865143	619	3.954378038	661	4.028838783	677	0.97251046	-0.060668376	normal	0.941337325	-0.229859262	normal	0.973084156	-0.072726093	normal	0.613385829	-0.125407941	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K02223|0|hsa:9575|CLOCK, KAT13D, bHLHe8; clock circadian regulator (EC:2.3.1.48); K02223 circadian locomoter output cycles kaput protein [EC:2.3.1.48] (A)"	Circadian rhythm (ko04710);; Dopaminergic synapse (ko04728);; Herpes simplex infection (ko05168)	[K]	Transcription	PAS domain;; PAS fold;; PAS fold;; Helix-loop-helix DNA-binding domain	Circadian locomoter output cycles protein kaput GN=CLOCK OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: circadian locomoter output cycles protein kaput isoform X1 [Myotis davidii] 
ENSG00000134853(PDGFRA)	--	9.511551112	465	9.682512583	424	8.56148604	418	10.08482673	496	10.80167048	509	8.814717976	425	0.969590838	0.062078527	normal	0.930738964	0.241388144	normal	0.970132253	0.015612439	normal	0.715986195	0.108077796	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04363|0|hsa:5156|PDGFRA, CD140A, PDGFR-2, PDGFR2, RHEPDGFRA; platelet-derived growth factor receptor, alpha polypeptide (EC:2.7.10.1); K04363 platelet-derived growth factor receptor alpha [EC:2.7.10.1] (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; Cytokine-cytokine receptor interaction (ko04060);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Platelet-derived growth factor receptor alpha (Precursor) GN=PDGFRA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: platelet-derived growth factor receptor alpha isoform X1 [Equus caballus] 
ENSG00000134864(GGACT)	--	14.24100928	159	4.804309553	138	8.389360767	110	7.175474442	133	9.699460002	177	12.988901	173	0.931819701	-0.285412425	normal	0.903939177	0.334411513	normal	0.394731595	0.637926634	normal	0.589171473	0.226167618	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	AIG2-like family	Gamma-glutamylaminecyclotransferase GN=GGACT OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: gamma-glutamylaminecyclotransferase isoform X1 [Mustela putorius furo] 
ENSG00000134871(COL4A2)	--	29.192817	4731	25.1384645	4179	30.176076	4996	59.802292	9700	72.762612	11621	46.2127026	7532	1.77E-07	1.004774808	up	2.22E-16	1.453749013	up	0.127104087	0.583823168	normal	0.000282319	1.031529784	up	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Cellular Component: collagen trimer (GO:0005581);; 	"K06237|0|hsa:1284|COL4A2, ICH, POREN2; collagen, type IV, alpha 2; K06237 collagen, type IV, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; C-terminal tandem repeated domain in type 4 procollagen	Canstatin (Precursor) GN=COL4A2 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: collagen alpha-2(IV) chain-like [Chrysochloris asiatica]
ENSG00000134873(CLDN10)	--	0	0	0	0	0	0	0	0	0	0	0.0291192	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|4.44621e-165|pps:100978259|CLDN10; claudin 10; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-10 GN=CLDN10 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: claudin-10 isoform 1 [Orcinus orca] 
ENSG00000134874(DZIP1)	--	9.542977186	954	8.900611955	881	10.03919525	953	7.9632744	805	9.4839593	940	7.71787928	769	0.919387066	-0.275349273	normal	0.975913804	0.071972565	normal	0.879708058	-0.317222542	normal	0.419100504	-0.170386024	normal	--	--	--	K16470|0|ggo:101135733|DZIP1; zinc finger protein DZIP1 isoform 1; K16470 zinc finger protein DZIP1 (A)	--	--	--	Iguana/Dzip1-like DAZ-interacting protein N-terminal	Zinc finger protein DZIP1 GN=DZIP1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: zinc finger protein DZIP1 [Odobenus rosmarus divergens]
ENSG00000134882(UBAC2)	--	32.04975276	1119	29.72407564	1101	28.2016886	1038	35.98299936	1295	36.09323771	1333	34.38898147	1310	0.966830727	0.179680324	normal	0.941587845	0.254118131	normal	0.876918958	0.327043882	normal	0.15478197	0.252223253	normal	--	--	--	--	--	[S]	Function unknown	UBA/TS-N domain	Ubiquitin-associated domain-containing protein 2 (Precursor) GN=UBAC2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: ubiquitin-associated domain-containing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000134884(ARGLU1)	--	24.52149293	1808	26.94606526	1971	25.1961913	1862	25.273634	1843	27.09324138	1979	26.632898	1982	0.98601388	-0.003168204	normal	0.986352634	-0.015570799	normal	0.984640889	0.081748086	normal	0.950458395	0.020104265	normal	--	--	--	K13173|4.68707e-19|tup:102492766|ARGLU1; arginine and glutamate rich 1; K13173 arginine and glutamate-rich protein 1 (A)	--	--	--	Arginine and glutamate-rich 1	Arginine and glutamate-rich protein 1 GN=ARGLU1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: arginine and glutamate-rich protein 1, partial [Camelus dromedarius]"
ENSG00000134897(BIVM)	--	13.37118935	935	12.74596509	914	14.47048351	1014	14.70441803	1041	14.99913973	1055	14.48687451	1061	0.972878606	0.123906517	normal	0.96177654	0.185264865	normal	0.978830163	0.056992462	normal	0.59683371	0.120074447	normal	--	--	--	--	--	--	--	--	Basic immunoglobulin-like variable motif-containing protein GN=BIVM OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: basic immunoglobulin-like variable motif-containing protein [Galeopterus variegatus] 
ENSG00000134900(TPP2)	--	11.241044	881	11.103609	883	10.691811	854	10.5477976	863	9.6499628	782	11.5786702	886	0.976491515	-0.060507101	normal	0.955915608	-0.196313848	normal	0.977219221	0.044701468	normal	0.794101537	-0.069971328	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	K01280|0|mcf:101865014|uncharacterized LOC101865014; K01280 tripeptidyl-peptidase II [EC:3.4.14.10] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tripeptidyl peptidase II;; Subtilase family	Tripeptidyl-peptidase 2 GN=TPP2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripeptidyl-peptidase 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000134901(KDELC1)	--	3.732467073	135	4.472953385	167	4.195001	155	5.4486496	204	5.3148	196	6.5635505	245	0.531505982	0.559564468	normal	0.946881936	0.207840225	normal	0.207849832	0.64715768	normal	0.114343904	0.476439944	normal	--	--	--	--	--	[R]	General function prediction only	Glycosyl transferase family 90;; Filamin/ABP280 repeat	KDEL motif-containing protein 1 (Precursor) GN=KDELC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: KDEL motif-containing protein 1 [Ailuropoda melanoleuca]
ENSG00000134905(CARS2)	--	22.51544965	666	22.51056547	688	25.679297	801	34.03947802	1041	26.34486121	802	40.16948928	1210	0.054279702	0.61240522	normal	0.953095573	0.199360926	normal	0.085191584	0.585935195	normal	0.087853452	0.482006848	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01883|0|hsa:79587|CARS2; cysteinyl-tRNA synthetase 2, mitochondrial (putative) (EC:6.1.1.16); K01883 cysteinyl-tRNA synthetase [EC:6.1.1.16] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (C) catalytic domain;; tRNA synthetases class I (M);; tRNA synthetases class I (I, L, M and V);; tRNA synthetases class I (K)"	"Probable cysteine--tRNA ligase, mitochondrial (Precursor) GN=CARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable cysteine--tRNA ligase, mitochondrial [Orycteropus afer afer]"
ENSG00000134909(ARHGAP32)	--	3.467423096	706	3.37536566	632	3.284584236	637	2.775296651	561	2.567682387	490	2.458469692	490	0.807002325	-0.36161456	normal	0.761583986	-0.387513139	normal	0.759867453	-0.385755767	normal	0.046150392	-0.379690565	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; PX domain	Rho GTPase-activating protein 32 GN=ARHGAP32 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 32 isoform 1 [Ceratotherium simum simum]
ENSG00000134910(STT3A)	--	61.75117917	2465	63.50199937	2560	64.3163893	2498	72.71712976	2923	65.05549442	2537	89.8131812	3473	0.973387739	0.214906798	normal	0.988401286	-0.03442642	normal	0.545769196	0.466876734	normal	0.302360918	0.227087631	normal	[R]	General function prediction only	Molecular Function: oligosaccharyl transferase activity (GO:0004576);; Biological Process: protein glycosylation (GO:0006486);; Cellular Component: membrane (GO:0016020);; 	"K07151|0|ptr:451648|STT3A; STT3A, subunit of the oligosaccharyltransferase complex (catalytic); K07151 dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.99.18] (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Oligosaccharyl transferase STT3 subunit;; Dolichyl-phosphate-mannose-protein mannosyltransferase	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A GN=STT3A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A [Oryctolagus cuniculus] 
ENSG00000134917(ADAMTS8)	--	0.0257474	2	0.012436	1	0.0366126	2	0.166645	13	0.287537	22	0.216206	17	--	--	--	0.008811808	3.212065668	up	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08623|0|hsa:11095|ADAMTS8, ADAM-TS8, METH2; ADAM metallopeptidase with thrombospondin type 1 motif, 8; K08623 a disintegrin and metalloproteinase with thrombospondin motifs 8 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Thrombospondin type 1 domain;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 8 (Precursor) GN=ADAMTS8 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 8 [Odobenus rosmarus divergens]
ENSG00000134940(ACRV1)	--	0.0597706	1	0.05973258	2	0.3429106	6	0.0388023	1	0.0379209	0	0.0911291	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Acrosomal protein SP-10 (Precursor) GN=ACRV1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sperm acrosomal protein FSA-ACR.1 isoformX3 [Canis lupus familiaris]
ENSG00000134954(ETS1)	--	5.600260744	540	6.83953259	654	6.680972591	634	12.66535364	1233	8.011297126	770	7.800108552	751	3.77E-09	1.158069697	up	0.947627911	0.213685466	normal	0.938507921	0.235521874	normal	0.175912675	0.568421615	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K02678|0|hsa:2113|ETS1, ETS-1, EWSR2, p54; v-ets avian erythroblastosis virus E26 oncogene homolog 1; K02678 c-ets proto-oncogene protein (A)"	Ras signaling pathway (ko04014);; Dorso-ventral axis formation (ko04320);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	Protein C-ets-1 GN=ETS1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transforming protein p68/c-ets-1 isoform X5 [Canis lupus familiaris]
ENSG00000134955(SLC37A2)	--	0.315161087	26	0.310317732	30	0.469691569	41	0.56417566	47	0.285838848	27	0.346208371	34	0.854029753	0.7882414	normal	0.983154104	-0.164674913	normal	0.976703619	-0.267529014	normal	0.894413486	0.133193228	normal	[G]	Carbohydrate transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13783|0|hsa:219855|SLC37A2, pp11662; solute carrier family 37 (glucose-6-phosphate transporter), member 2; K13783 MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Sugar phosphate exchanger 2 GN=SLC37A2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sugar phosphate exchanger 2 isoform X1 [Equus caballus] 
ENSG00000134962(KLB)	--	0.0846733	9	0.0755149	8	0.0655275	6	0.0654572	7	0.208536	22	0.194923	21	--	--	--	0.862770199	1.286516976	normal	0.742597605	1.576210168	normal	--	--	--	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 1	Beta-klotho GN=KLB OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: beta-klotho isoform X1 [Galeopterus variegatus]
ENSG00000134970(TMED7)	--	64.07199119	2943	66.18445955	3039	70.13369316	3155	67.19282403	3105	68.98390019	3089	64.02001858	3001	0.989859353	0.046449854	normal	0.990100238	0.002115594	normal	0.989070603	-0.080448585	normal	0.971868697	-0.012063633	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	K14825|2.09614e-161|ptr:471605|TMED7; transmembrane emp24 protein transport domain containing 7; K14825 protein ERP2 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 7 (Precursor) GN=TMED7 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 7 isoform X1 [Galeopterus variegatus]
ENSG00000134982(APC)	--	5.34695896	1119	5.318296059	1161	5.578980967	1160	5.261637441	1017	4.538644895	994	7.063696409	990	0.967117888	-0.168479836	normal	0.943011102	-0.245131284	normal	0.946704596	-0.236581581	normal	0.243798979	-0.218213489	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: beta-catenin binding (GO:0008013);; Molecular Function: microtubule binding (GO:0008017);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K02085|0|hsa:324|APC, BTPS2, DP2, DP2.5, DP3, GS, PPP1R46; adenomatous polyposis coli; K02085 adenomatosis polyposis coli protein (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Basal cell carcinoma (ko05217)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	APC basic domain;; EB-1 Binding Domain;; APC cysteine-rich region;; Armadillo/beta-catenin-like repeat;; Adenomatous polyposis coli tumour suppressor protein;; SAMP Motif;; APC 15 residue motif	Adenomatous polyposis coli protein GN=APC OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: adenomatous polyposis coli protein isoform 1 [Odobenus rosmarus divergens] 
ENSG00000134986(NREP)	--	11.67956374	334	7.936190275	226	7.392965679	204	8.062514684	256	13.2018513	367	10.51764706	266	0.753081294	-0.412362527	normal	0.07270916	0.674456872	normal	0.843277216	0.372143004	normal	0.713453307	0.197262331	normal	--	--	--	--	--	--	--	Neuronal protein 3.1 (p311)	Neuronal regeneration-related protein GN=NREP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuronal regeneration-related protein isoformX1 [Equus caballus] 
ENSG00000134987(WDR36)	--	12.73952367	1219	14.3177741	1329	14.60342776	1317	13.27182173	1247	14.17231928	1242	11.764698	1076	0.981928627	0.001928672	normal	0.976725988	-0.118962423	normal	0.908351456	-0.299487563	normal	0.514354901	-0.138115125	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: rRNA processing (GO:0006364);; Cellular Component: small-subunit processome (GO:0032040);; 	"K14554|0|hsa:134430|WDR36, GLC1G, TA-WDRP, TAWDRP, UTP21; WD repeat domain 36; K14554 U3 small nucleolar RNA-associated protein 21 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	"Utp21 specific WD40 associated putative domain;; WD domain, G-beta repeat"	WD repeat-containing protein 36 GN=WDR36 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 36 [Equus przewalskii]
ENSG00000134996(OSTF1)	--	8.597423	193	7.32265	167	7.755729	175	13.210662	301	11.121912	249	10.268945	232	0.23630711	0.60643618	normal	0.477054517	0.550761828	normal	0.829385036	0.395500774	normal	0.047634761	0.525583096	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Ankyrin repeat	Osteoclast-stimulating factor 1 GN=OSTF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: osteoclast-stimulating factor 1 [Galeopterus variegatus]
ENSG00000135002(RFK)	--	49.851407	1784	55.60880223	1994	47.96600184	1692	44.97440473	1638	53.51320293	1923	59.46870312	2140	0.976955936	-0.153874159	normal	0.984855771	-0.0736763	normal	0.894287861	0.330326688	normal	0.900681346	0.039087921	normal	[H]	Coenzyme transport and metabolism	Molecular Function: riboflavin kinase activity (GO:0008531);; Biological Process: riboflavin biosynthetic process (GO:0009231);; 	"K00861|1.32343e-112|hsa:55312|RFK, RIFK; riboflavin kinase (EC:2.7.1.26); K00861 riboflavin kinase [EC:2.7.1.26] (A)"	Riboflavin metabolism (ko00740)	[H]	Coenzyme transport and metabolism	Riboflavin kinase	Riboflavin kinase GN=RFK OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: riboflavin kinase isoform X1 [Sus scrofa]
ENSG00000135018(UBQLN1)	--	72.43345058	4771	74.30244588	4956	72.9945648	4720	72.027067	4755	70.9932371	4675	61.82779297	4074	0.992997554	-0.035667103	normal	0.991243434	-0.105603195	normal	0.980209761	-0.220556185	normal	0.587616794	-0.119062618	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K04523|0|cjc:100394790|UBQLN1; ubiquilin 1; K04523 ubiquilin (A)	Protein processing in endoplasmic reticulum (ko04141)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like;; UBA/TS-N domain	Ubiquilin-1 GN=UBQLN1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ubiquilin-1 [Equus caballus]
ENSG00000135040(NAA35)	--	18.7749708	937	18.70123	922	16.1432119	789	16.630631	824	17.64039007	872	17.129172	843	0.950705429	-0.215859189	normal	0.973492459	-0.101693626	normal	0.974067392	0.087054439	normal	0.750819832	-0.082017333	normal	--	--	--	--	--	[R]	General function prediction only	"Mak10 subunit, NatC N(alpha)-terminal acetyltransferase"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit GN=NAA35 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: N-alpha-acetyltransferase 35, NatC auxiliary subunit isoformX1 [Canis lupus familiaris]"
ENSG00000135045(C9orf40)	--	9.28543	284	9.04156	283	9.56453	296	14.0091	439	14.8755	458	14.7077	454	0.165073602	0.594890871	normal	0.052408594	0.670278119	normal	0.133758613	0.60628411	normal	0.002067505	0.625603618	normal	--	--	--	--	--	--	--	Drug resistance and apoptosis regulator	Uncharacterized protein C9orf40 GN=C9orf40 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf40 homolog [Physeter catodon]
ENSG00000135046(ANXA1)	--	606.4723261	17706	505.4458603	14613	647.2323882	18541	706.4119799	20718	668.0340591	19429	528.802239	15466	0.995114687	0.195798431	normal	0.945090522	0.389497638	normal	0.988630519	-0.269886244	normal	0.713453307	0.107165828	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	K17091|0|pps:100994302|ANXA1; annexin A1; K17091 annexin A1 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A1 GN=ANXA1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A1 [Orycteropus afer afer]
ENSG00000135047(CTSL)	--	279.56351	8061	286.7485029	8700	272.91011	8180	177.19816	5298	162.39365	4688	265.95576	7761	0.038105959	-0.636192459	normal	9.56E-06	-0.913249509	normal	0.994745153	-0.08413376	normal	0.045752977	-0.511071189	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K01365|0|ptr:737449|CTSL, CTSL1; cathepsin L; K01365 cathepsin L [EC:3.4.22.15] (A)"	Lysosome (ko04142);; Phagosome (ko04145);; Antigen processing and presentation (ko04612);; Proteoglycans in cancer (ko05205);; Rheumatoid arthritis (ko05323)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin propeptide inhibitor domain (I29);; Peptidase C1-like family	Cathepsin L1 light chain (Precursor) GN=CTSL OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin L1 [Galeopterus variegatus]
ENSG00000135048(TMEM2)	--	49.96263927	5493	49.46822285	5687	52.41206083	5932	42.22535013	4906	47.32026345	5346	58.96601183	6692	0.986145181	-0.193821915	normal	0.991949396	-0.110604182	normal	0.990296127	0.165587639	normal	0.91179757	-0.034392298	normal	--	--	--	--	--	--	--	G8 domain	Transmembrane protein 2 GN=TMEM2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 2 isoform X1 [Leptonychotes weddellii]
ENSG00000135049(AGTPBP1)	--	10.1188998	816	8.421781978	670	8.35060893	657	8.31184964	686	8.478188496	681	9.26347906	758	0.912028295	-0.280615686	normal	0.974414346	0.002062527	normal	0.953232031	0.197589277	normal	0.916032746	-0.033244374	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[E]	Amino acid transport and metabolism	Zinc carboxypeptidase	Cytosolic carboxypeptidase 1 GN=AGTPBP1 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: cytosolic carboxypeptidase 1 isoform X2 [Equus caballus]
ENSG00000135052(GOLM1)	--	74.49363408	5016	65.80721635	4513	73.32767054	4955	97.305112	6632	93.99387608	6318	87.77907383	5933	0.903904583	0.371975034	normal	0.66763572	0.463822677	normal	0.977216332	0.251515043	normal	0.026845798	0.361199265	normal	--	--	--	--	--	--	--	--	Golgi membrane protein 1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi membrane protein 1 isoform X1 [Physeter catodon]
ENSG00000135063(FAM189A2)	--	0.086342226	3	0.297533069	12	0.194956328	7	0.299155	12	0.241840098	9	0.197429664	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	CD20-like family	Protein FAM189A2 (Precursor) GN=FAM189A2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM189A2 [Tupaia chinensis]
ENSG00000135069(PSAT1)	--	151.5544216	4884	156.7567147	5092	147.4905935	4730	96.47303294	3161	79.61230313	2564	159.7541226	5214	0.016745264	-0.658254798	normal	2.27E-07	-1.010830952	down	0.990487491	0.13221868	normal	0.27146356	-0.44671371	normal	[HE]	Coenzyme transport and metabolism;; Amino acid transport and metabolism	--	K00831|0|pps:100984963|PSAT1; phosphoserine aminotransferase 1; K00831 phosphoserine aminotransferase [EC:2.6.1.52] (A)	"Glycine, serine and threonine metabolism (ko00260);; Vitamin B6 metabolism (ko00750);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[HE]	Coenzyme transport and metabolism;; Amino acid transport and metabolism	Aminotransferase class-V	Phosphoserine aminotransferase GN=PSAT1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: phosphoserine aminotransferase [Pteropus alecto]
ENSG00000135070(ISCA1)	--	31.00078591	843	27.53608147	774	29.94232384	821	31.67013484	844	26.969236	764	30.65862092	818	0.977231461	-0.029068947	normal	0.97530063	-0.040108608	normal	0.977238563	-0.01354782	normal	0.929935575	-0.028397279	normal	[S]	Function unknown	--	K13628|5.35742e-90|ptr:736509|ISCA1; iron-sulfur cluster assembly 1 homolog (S. cerevisiae) (EC:2.7.7.52); K13628 iron-sulfur cluster assembly protein (A)	--	[P]	Inorganic ion transport and metabolism	Iron-sulphur cluster biosynthesis	"Iron-sulfur cluster assembly 1 homolog, mitochondrial (Precursor) GN=ISCA1 OS=Homo sapiens (Human) PE=2 SV=1"	P	Inorganic ion transport and metabolism	"PREDICTED: iron-sulfur cluster assembly 1 homolog, mitochondrial [Ochotona princeps] "
ENSG00000135074(ADAM19)	--	6.636572954	854	6.571948094	841	6.333735511	816	16.49635087	2161	19.60828633	2517	10.06670109	1329	1.18E-12	1.307029567	up	0	1.558401239	up	0.007293419	0.694390452	normal	0.00470935	1.236055844	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K08608|0|mcf:102143685|ADAM19; ADAM metallopeptidase domain 19; K08608 disintegrin and metalloproteinase domain-containing protein 19 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Reprolysin family propeptide;; Disintegrin;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 19 (Precursor) GN=ADAM19 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 19 [Ceratotherium simum simum]
ENSG00000135077(HAVCR2)	--	9.40282512	400	9.5065758	404	9.1980978	384	9.1929988	397	7.296653007	313	7.73983	353	0.968895935	-0.041533121	normal	0.78412416	-0.387964339	normal	0.960987601	-0.129198706	normal	0.519581419	-0.182127859	normal	--	--	--	--	--	--	--	Immunoglobulin V-set domain	Hepatitis A virus cellular receptor 2 (Precursor) GN=HAVCR2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: hepatitis A virus cellular receptor 2 isoform X1 [Galeopterus variegatus]
ENSG00000135083(CCNJL)	--	9.358549234	591	11.41018798	714	9.532074914	599	6.95229004	448	6.989303475	447	8.33632254	546	0.644666898	-0.429205383	normal	0.015909679	-0.695196822	normal	0.96315689	-0.141571974	normal	0.024797462	-0.42276775	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	--	--	--	--	"Cyclin, C-terminal domain;; Cyclin, N-terminal domain"	Cyclin-J-like protein GN=CCNJL OS=Homo sapiens (Human) PE=2 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-J-like protein [Galeopterus variegatus]
ENSG00000135090(TAOK3)	--	11.64783707	826	11.5939117	914	8.941915734	810	10.38208472	820	10.12244147	782	9.761649467	837	0.976594944	-0.041273083	normal	0.937170056	-0.246011532	normal	0.976761706	0.038942746	normal	0.739931605	-0.08550468	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04429|0|hsa:51347|TAOK3, DPK, JIK, MAP3K18; TAO kinase 3 (EC:2.7.11.1); K04429 thousand and one amino acid protein kinase [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase TAO3 GN=TAOK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase TAO3 isoform X1 [Pteropus alecto] 
ENSG00000135093(USP30)	--	4.766805255	297	4.71738013	275	3.70740716	230	4.783515302	313	4.891446051	269	3.885912037	251	0.967024562	0.044642496	normal	0.965206395	-0.052957539	normal	0.961242021	0.117025293	normal	0.946007535	0.032466385	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11851|0|ptr:452215|USP30; ubiquitin specific peptidase 30; K11851 ubiquitin carboxyl-terminal hydrolase 30 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 30 GN=USP30 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 30 [Trichechus manatus latirostris]
ENSG00000135094(SDS)	--	0.0747583	2	0	0	0	0	0.0745553	2	0.218552045	5	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	--	"K17989|0|hsa:10993|SDS, SDH; serine dehydratase (EC:4.3.1.17 4.3.1.19); K17989 L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Cysteine and methionine metabolism (ko00270);; Valine, leucine and isoleucine biosynthesis (ko00290);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Pyridoxal-phosphate dependent enzyme	L-serine dehydratase/L-threonine deaminase GN=SDS OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: L-serine dehydratase/L-threonine deaminase [Leptonychotes weddellii]
ENSG00000135097(MSI1)	--	0.911413677	49	0.4118171	23	0.5036274	27	0.6976505	37	0.829283921	44	0.427743668	23	0.960031014	-0.420849386	normal	0.809621555	0.872341375	normal	0.984652679	-0.225894447	normal	0.976887251	0.048542516	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K14411|0|hsa:4440|MSI1; musashi RNA-binding protein 1; K14411 RNA-binding protein Musashi (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein Musashi homolog 1 GN=MSI1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein Musashi homolog 1 [Oryctolagus cuniculus]
ENSG00000135100(HNF1A)	--	0	0	0.070862	3	0	0	2.559009205	127	3.241075344	163	2.709668	147	0	6.37125568	up	0	5.170458591	up	0	6.613607468	up	7.39E-37	7.162540393	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	"K08036|0|hsa:6927|HNF1A, HNF-1A, HNF1, IDDM20, LFB1, MODY3, TCF-1, TCF1; HNF1 homeobox A; K08036 transcription factor 1, hepatocyte nuclear factor 1-alpha (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550);; Maturity onset diabetes of the young (ko04950)	--	--	"Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus;; Hepatocyte nuclear factor 1 (HNF-1), N terminus;; Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus;; Homeobox domain"	Hepatocyte nuclear factor 1-alpha GN=HNF1A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: hepatocyte nuclear factor 1-alpha isoform 1 [Ceratotherium simum simum]
ENSG00000135108(FBXO21)	--	24.32065842	1698	23.69653007	1606	23.09135513	1578	24.69712372	1669	26.27303211	1828	23.93951043	1594	0.98431755	-0.05563399	normal	0.975110452	0.165221716	normal	0.984638445	0.006257016	normal	0.887107961	0.039145277	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; 	K10301|0|ptr:452287|FBXO21; F-box protein 21; K10301 F-box protein 21 (A)	--	--	--	Transglutaminase-like superfamily;; Hemimethylated DNA-binding protein YccV like;; F-box-like	F-box only protein 21 GN=FBXO21 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: F-box only protein 21 isoform X1 [Galeopterus variegatus]
ENSG00000135111(TBX3)	--	6.15505	471	4.56474	340	4.60254	348	7.25504	553	10.18359	778	5.82138	449	0.948005994	0.200117234	normal	2.95E-08	1.169275937	up	0.826396244	0.357963691	normal	0.176210516	0.597313677	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10177|0|ptr:740308|TBX3; T-box 3; K10177 T-box protein 3 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[K]	Transcription	T-box;; T-box transcription factor	T-box transcription factor TBX3 GN=TBX3 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: T-box transcription factor TBX3 isoform 1 [Trichechus manatus latirostris]
ENSG00000135114(OASL)	--	0.157618908	10	0.173933675	9	0.156085377	10	1.325742535	67	1.794408002	90	0.477654898	22	4.43E-07	2.542236874	up	6.24E-12	3.10218098	up	0.937668826	1.022760185	normal	0.025179632	2.602838294	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K14608|0|ptr:452317|OASL; 2'-5'-oligoadenylate synthetase-like; K14608 2'-5'-oligoadenylate synthase-like protein (A)	--	--	--	"2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus;; Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like"	2'-5'-oligoadenylate synthase-like protein GN=OASL OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 2'-5'-oligoadenylate synthase-like protein [Ceratotherium simum simum]
ENSG00000135116(HRK)	--	0.01054316	1	0.093287471	9	0.031038955	2	0.179339958	17	0.030871683	2	0.304847371	29	--	--	--	--	--	--	0.000812502	3.112607241	up	--	--	--	--	--	--	"K02512|2.56258e-32|hgl:101715325|Hrk; harakiri, BCL2 interacting protein (contains only BH3 domain); K02512 activator of apoptosis harakiri (neural death protein DP5), BCL2-interacting (A)"	--	--	--	Activator of apoptosis harakiri	Activator of apoptosis harakiri GN=HRK OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: activator of apoptosis harakiri [Lipotes vexillifer]
ENSG00000135119(RNFT2)	--	3.4776807	239	4.169746645	258	3.3663108	261	3.2362261	212	2.540213351	161	3.560525325	242	0.94692476	-0.202396027	normal	0.105109012	-0.696518474	normal	0.961283316	-0.116632194	normal	0.276895413	-0.322436365	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[S]	Function unknown	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger and transmembrane domain-containing protein 2 GN=RNFT2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger and transmembrane domain-containing protein 2 [Orycteropus afer afer]
ENSG00000135124(P2RX4)	--	12.13490886	451	11.51480405	429	10.2504069	385	9.994570932	315	8.682841137	316	17.42511943	647	0.285139744	-0.546367417	normal	0.598906341	-0.460579888	normal	0.006345228	0.738354075	normal	0.998695285	-0.004469704	normal	--	--	Molecular Function: purinergic nucleotide receptor activity (GO:0001614);; Molecular Function: extracellular ATP-gated cation channel activity (GO:0004931);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: response to ATP (GO:0033198);; Biological Process: cation transmembrane transport (GO:0098655);; 	"K05218|0|hsa:5025|P2RX4, P2X4, P2X4R; purinergic receptor P2X, ligand-gated ion channel, 4; K05218 P2X purinoceptor 4 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	--	--	ATP P2X receptor	P2X purinoceptor 4 GN=P2RX4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: P2X purinoceptor 4 isoform X1 [Eptesicus fuscus]
ENSG00000135127(BICDL1)	--	5.176765083	393	5.294598057	424	3.843576095	312	1.018577468	79	1.34100306	94	2.932987177	227	0	-2.32292254	down	0	-2.176661379	down	0.645673299	-0.464494251	normal	0.000106247	-1.515466333	down	--	--	--	"K16756|0|hsa:92558|CCDC64, BICDR-1, H_267D11.1; coiled-coil domain containing 64; K16756 coiled-coil domain-containing protein 64 (A)"	--	--	--	--	Bicaudal D-related protein 1 GN=CCDC64 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: bicaudal D-related protein 1 isoform X1 [Mustela putorius furo]
ENSG00000135144(DTX1)	--	0.7866038	63	0.144855075	12	0.532674	40	0.1994408	16	0.524095	39	0.126293263	9	0.000220135	-1.908870891	down	0.130914234	1.564260229	normal	0.009099992	-1.989005814	down	0.566439982	-0.866663022	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K06058|0|hsa:1840|DTX1, hDx-1; deltex 1, E3 ubiquitin ligase; K06058 deltex (A)"	Notch signaling pathway (ko04330)	--	--	"WWE domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase DTX1 GN=DTX1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase DTX1 [Orcinus orca]
ENSG00000135148(TRAFD1)	--	8.243259716	451	10.34915061	578	9.327883372	518	13.5465594	749	13.48003705	735	13.09614679	722	0.011993355	0.699139736	normal	0.868195414	0.324493738	normal	0.486963386	0.469588937	normal	0.005132373	0.490622945	normal	--	--	--	--	--	--	--	--	TRAF-type zinc finger domain-containing protein 1 GN=TRAFD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: TRAF-type zinc finger domain-containing protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000135164(DMTF1)	--	14.63033655	970	12.49159375	961	13.00677316	881	16.0036131	937	14.15904225	900	15.06477173	952	0.976418044	-0.080637993	normal	0.97257102	-0.115849557	normal	0.974158413	0.103357402	normal	0.911176091	-0.03316706	normal	[KAD]	"Transcription;; RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	--	--	--	[K]	Transcription	Myb-like DNA-binding domain;; Myb-like DNA-binding domain	Cyclin-D-binding Myb-like transcription factor 1 GN=DMTF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cyclin-D-binding Myb-like transcription factor 1 isoform X1 [Galeopterus variegatus] 
ENSG00000135185(TMEM243)	--	13.021705	231	12.219214	225	11.67732891	214	14.913131	271	15.181106	266	15.612006	275	0.947087339	0.198348795	normal	0.940476499	0.218721374	normal	0.863305275	0.351333785	normal	0.402534623	0.256059805	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2678)	Transmembrane protein 243 GN=TMEM243 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 243 [Galeopterus variegatus] 
ENSG00000135205(CCDC146)	--	1.3575534	117	1.028532107	70	0.736602051	62	0.900280351	78	1.654634398	146	1.03539512	58	0.673596632	-0.605977169	normal	0.009558406	1.023481887	up	0.975207217	-0.101935539	normal	0.895327936	0.157567475	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 146 GN=CCDC146 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 146 [Galeopterus variegatus]
ENSG00000135211(TMEM60)	--	21.6772	267	26.7745	335	24.3448	300	17.7723	222	18.2141	224	22.769	282	0.90806099	-0.2952459	normal	0.226412062	-0.598759707	normal	0.963544505	-0.097054069	normal	0.220711329	-0.32972908	normal	--	--	--	--	--	[S]	Function unknown	Transmembrane Fragile-X-F protein	Transmembrane protein 60 GN=TMEM60 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 60 [Orycteropus afer afer]
ENSG00000135218(CD36)	--	0.204578667	5	0.403470062	3	0.036683212	0	0.237025223	4	0.410759076	12	0.189489416	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	"K06259|0|hsa:948|CD36, BDPLT10, CHDS7, FAT, GP3B, GP4, GPIV, PASIV, SCARB3; CD36 molecule (thrombospondin receptor); K06259 CD36 antigen (A)"	PPAR signaling pathway (ko03320);; Phagosome (ko04145);; AMPK signaling pathway (ko04152);; ECM-receptor interaction (ko04512);; Hematopoietic cell lineage (ko04640);; Adipocytokine signaling pathway (ko04920);; Fat digestion and absorption (ko04975);; Malaria (ko05144)	[T]	Signal transduction mechanisms	CD36 family	Platelet glycoprotein 4 GN=CD36 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: platelet glycoprotein 4 [Oryctolagus cuniculus] 
ENSG00000135220(UGT2A3)	--	0	0	0	0	0	0	0.115799	5	0.226955	9	0.139377	6	--	--	--	--	--	--	--	--	--	--	--	--	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00699|0|hsa:79799|UGT2A3; UDP glucuronosyltransferase 2 family, polypeptide A3 (EC:2.4.1.17); K00699 glucuronosyltransferase [EC:2.4.1.17] (A)"	Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Steroid hormone biosynthesis (ko00140);; Starch and sucrose metabolism (ko00500);; Retinol metabolism (ko00830);; Porphyrin and chlorophyll metabolism (ko00860);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain	UDP-glucuronosyltransferase 2A3 (Precursor) GN=UGT2A3 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronosyltransferase 2A3 isoform X1 [Galeopterus variegatus]
ENSG00000135241(PNPLA8)	--	7.812336139	468	9.940994909	585	9.402242972	556	8.168989707	496	7.970082971	487	14.7590581	900	0.970113146	0.052830847	normal	0.904961664	-0.285132252	normal	0.012904736	0.68507031	normal	0.765800969	0.207535024	normal	[R]	General function prediction only	Biological Process: lipid metabolic process (GO:0006629);; 	"K16815|0|hsa:50640|PNPLA8, IPLA2(GAMMA), IPLA2-2, IPLA2G, iPLA2gamma; patatin-like phospholipase domain containing 8 (EC:3.1.1.5); K16815 calcium-independent phospholipase A2-gamma (A)"	--	[I]	Lipid transport and metabolism	Patatin-like phospholipase	Calcium-independent phospholipase A2-gamma GN=PNPLA8 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: calcium-independent phospholipase A2-gamma isoform X1 [Tupaia chinensis]
ENSG00000135245(HILPDA)	--	74.44145	2503	90.45727	3094	78.05065	2432	28.49569	934	29.45917	1037	32.67271	1109	5.55E-16	-1.451475299	down	0	-1.597065621	down	1.20E-09	-1.140097923	down	1.08E-13	-1.403237676	down	--	--	--	--	--	--	--	Hypoxia-inducible lipid droplet-associated	Hypoxia-inducible lipid droplet-associated protein GN=HILPDA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: hypoxia-inducible lipid droplet-associated protein [Capra hircus]
ENSG00000135248(FAM71F1)	--	0	0	0.121065536	4	0	0	0	0	0.056063987	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF3699)	Protein FAM71F1 GN=FAM71F1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM71F1 [Galeopterus variegatus]
ENSG00000135249(RINT1)	--	8.471307296	441	9.08264	471	10.18208	521	9.371566	488	10.82502678	562	9.115317	472	0.964591452	0.114889629	normal	0.935566344	0.232731702	normal	0.960041176	-0.150329303	normal	0.839424806	0.065959623	normal	--	--	Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: Golgi vesicle transport (GO:0048193);; 	--	--	[UD]	"Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	RINT-1 / TIP-1 family	RAD50-interacting protein 1 GN=RINT1 OS=Homo sapiens (Human) PE=1 SV=1	DU	"Cell cycle control, cell division, chromosome partitioning;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: RAD50-interacting protein 1 [Sus scrofa]
ENSG00000135250(SRPK2)	--	20.3986021	1260	24.61390214	1476	18.74501576	1169	21.31020005	1358	20.67658904	1243	22.63345594	1337	0.980531228	0.077136871	normal	0.936458195	-0.268992228	normal	0.966382724	0.185208902	normal	0.981359573	-0.009440905	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08831|0|mcf:101867513|hypothetical protein; K08831 serine/threonine-protein kinase SRPK2 [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	SRSF protein kinase 2 C-terminal OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SRSF protein kinase 2 [Oryctolagus cuniculus]
ENSG00000135253(KCP)	--	0.023404446	2	0.034679208	3	0.033510643	2	0.094360784	8	0.102848354	8	0.334686371	30	--	--	--	--	--	--	0.000466589	3.159124861	up	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type C domain;; von Willebrand factor type D domain;; TILa domain	Kielin/chordin-like protein (Precursor) GN=KCP OS=Homo sapiens (Human) PE=2 SV=2	VW	Defense mechanisms;; Extracellular structures	PREDICTED: kielin/chordin-like protein isoform X5 [Mustela putorius furo]
ENSG00000135269(TES)	--	13.5289878	655	13.36253395	675	14.25734912	669	30.43959825	1486	25.90379168	1238	23.59463948	1154	2.86E-09	1.149197705	up	0.000151814	0.852194989	normal	0.000993581	0.776920259	normal	1.28E-09	0.934037642	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	PET Domain;; LIM domain	Testin GN=TES OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: testin [Capra hircus]
ENSG00000135272(MDFIC)	--	14.8599035	857	20.1740433	1059	17.1166933	881	12.2941702	782	12.991824	780	17.37789106	923	0.964050425	-0.162653437	normal	0.513936354	-0.461811424	normal	0.977064821	0.058798572	normal	0.354498536	-0.191535757	normal	--	--	--	--	--	--	--	MyoD family inhibitor	MyoD family inhibitor domain-containing protein OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: myoD family inhibitor domain-containing protein isoform 1 [Ceratotherium simum simum] 
ENSG00000135297(MTO1)	--	5.061091084	268	6.398825828	325	4.248141591	265	4.9569126	291	5.67642725	295	6.886052558	386	0.964153306	0.087472577	normal	0.954037102	-0.160367692	normal	0.379057645	0.531788267	normal	0.621092743	0.159384031	normal	--	--	Biological Process: tRNA processing (GO:0008033);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K03495|0|hsa:25821|MTO1, COXPD10; mitochondrial tRNA translation optimization 1; K03495 tRNA uridine 5-carboxymethylaminomethyl modification enzyme (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Glucose inhibited division protein A;; GidA associated domain 3;; FAD dependent oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain	"Protein MTO1 homolog, mitochondrial (Precursor) GN=MTO1 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: protein MTO1 homolog, mitochondrial isoform 2 [Orcinus orca]"
ENSG00000135298(ADGRB3)	--	0	0	0	0	0	0	0	0	0	0	0.00870279	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	K04598|0|ptr:462808|BAI3; brain-specific angiogenesis inhibitor 3; K04598 brain-specific angiogenesis inhibitor 3 (A)	--	--	--	7 transmembrane receptor (Secretin family);; Domain of unknown function (DUF3497);; Thrombospondin type 1 domain;; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain	Brain-specific angiogenesis inhibitor 3 (Precursor) GN=BAI3 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: brain-specific angiogenesis inhibitor 3 isoform X1 [Felis catus] 
ENSG00000135299(ANKRD6)	--	2.297671538	152	2.950614079	135	1.792415658	132	2.339413411	143	2.53403074	204	2.01447017	155	0.963494559	-0.117661937	normal	0.50744182	0.56896479	normal	0.949727608	0.221098974	normal	0.554453831	0.239813406	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 6 GN=ANKRD6 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 6 isoform X1 [Pteropus alecto]
ENSG00000135312(HTR1B)	--	2.006354	114	2.50729	134	1.736658	104	0.2881247	12	0.1873393	13	0.1324985	8	4.55E-15	-3.122302458	down	0	-3.243267635	down	1.44E-15	-3.479047813	down	8.93E-17	-3.437538546	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04153|0|ptr:462833|HTR1B; 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled; K04153 5-hydroxytryptamine receptor 1 (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Serotonergic synapse (ko04726)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	5-hydroxytryptamine receptor 1B GN=HTR1B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 5-hydroxytryptamine receptor 1B-like [Tupaia chinensis] 
ENSG00000135314(KHDC1)	--	3.89439876	100	2.971044363	79	5.97472584	122	3.23585696	78	5.386283542	111	2.94541357	73	0.923664362	-0.382610738	normal	0.869362068	0.461720342	normal	0.359063663	-0.73726085	normal	0.678807371	-0.220730114	normal	--	--	--	--	--	--	--	--	KH homology domain-containing protein 1 GN=KHDC1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: KH homology domain-containing protein 1-like [Galeopterus variegatus] 
ENSG00000135315(CEP162)	--	1.091404557	131	1.398888812	165	1.541755221	180	1.139492599	137	1.386927876	166	1.240724681	149	0.968270996	0.033393833	normal	0.966128948	-0.01259426	normal	0.929951289	-0.27840119	normal	0.850687514	-0.095188079	normal	--	--	--	K16809|0|pps:100980048|CEP162; centrosomal protein 162kDa; K16809 protein QN1 (A)	--	--	--	--	Centrosomal protein of 162 kDa GN=CEP162 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein QN1 homolog [Odobenus rosmarus divergens]
ENSG00000135316(SYNCRIP)	--	59.1095921	3642	66.00248659	3907	65.3267543	3910	71.39557983	4598	72.9694454	4449	63.61543604	4142	0.949409503	0.305328432	normal	0.986460843	0.165933065	normal	0.991235864	0.074839377	normal	0.345098712	0.181410372	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13160|0|ptr:462866|SYNCRIP; synaptotagmin binding, cytoplasmic RNA interacting protein; K13160 heterogeneous nuclear ribonucleoprotein Q (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoprotein Q GN=SYNCRIP OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein Q isoformX1 [Equus caballus]
ENSG00000135317(SNX14)	--	25.71442307	1195	23.22857924	1145	22.09680105	1119	19.61604893	1034	21.3912307	1090	20.78823232	1000	0.94611998	-0.2392756	normal	0.977183452	-0.092321029	normal	0.966739855	-0.170257935	normal	0.404658547	-0.16828006	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17926|0|pps:100983572|SNX14; sorting nexin 14; K17926 sorting nexin-14 (A)	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	PXA domain;; Sorting nexin C terminal;; PX domain;; Regulator of G protein signaling domain	Sorting nexin-14 GN=SNX14 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-14 isoform X1 [Tupaia chinensis]
ENSG00000135318(NT5E)	--	12.81308124	775	9.4158333	535	13.0033475	717	45.90344558	2525	30.99176129	1701	18.27095	1023	0	1.671243018	up	0	1.644595244	up	0.326058605	0.503575956	normal	0.049012387	1.349104524	normal	[F]	Nucleotide transport and metabolism	Biological Process: nucleotide catabolic process (GO:0009166);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01081|0|ptr:462864|NT5E; 5'-nucleotidase, ecto (CD73); K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	[F]	Nucleotide transport and metabolism	"5'-nucleotidase, C-terminal domain;; Calcineurin-like phosphoesterase"	5'-nucleotidase (Precursor) GN=NT5E OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: 5'-nucleotidase [Mustela putorius furo]
ENSG00000135324(MRAP2)	--	0.673076553	24	0.94953845	34	0.886012552	31	1.924303903	69	2.10286848	75	2.312154628	83	0.010014136	1.436241224	normal	0.123072643	1.086614568	normal	0.004654086	1.370151608	up	0.00241335	1.330239042	up	--	--	--	--	--	--	--	Melanocortin-2 receptor accessory protein family	Melanocortin-2 receptor accessory protein 2 GN=MRAP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: melanocortin-2 receptor accessory protein 2 [Panthera tigris altaica]
ENSG00000135333(EPHA7)	--	0	0	0	0	0	0	0.73371546	83	0.680191279	62	0.694105601	59	0	5.766819652	up	9.45E-14	5.381810483	up	3.65E-13	5.3183866	up	3.13E-22	Inf	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05108|0|tup:102474133|EPHA7; EPH receptor A7; K05108 EphA7 [EC:2.7.10.1] (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; GCC2 and GCC3	Ephrin type-A receptor 7 (Precursor) GN=EPHA7 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 7 isoform 2 [Trichechus manatus latirostris] 
ENSG00000135334(AKIRIN2)	--	33.7674	529	36.6699	632	31.927	549	35.3008	588	36.4638	598	38.9693	651	0.965702424	0.121381692	normal	0.968643906	-0.100957238	normal	0.935743609	0.236959858	normal	0.777826316	0.082330775	normal	--	--	--	--	--	[S]	Function unknown	--	Akirin-2 GN=AKIRIN2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: akirin-2 [Eptesicus fuscus]
ENSG00000135336(ORC3)	--	11.24230432	488	12.278618	529	14.29561357	607	12.48853319	552	10.63386897	468	10.75261008	475	0.96104244	0.146520936	normal	0.94807789	-0.197584763	normal	0.811173734	-0.36104096	normal	0.594330135	-0.140798606	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nuclear origin of replication recognition complex (GO:0005664);; Biological Process: DNA replication (GO:0006260);; 	"K02605|0|pps:100992107|ORC3; origin recognition complex, subunit 3; K02605 origin recognition complex subunit 3 (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	Origin recognition complex (ORC) subunit 3 N-terminus	Origin recognition complex subunit 3 GN=ORC3 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: origin recognition complex subunit 3 isoform X1 [Galeopterus variegatus]
ENSG00000135338(LCA5)	--	1.107232814	93	1.288633793	108	1.695285401	144	1.073201428	92	0.985703809	84	1.401481143	121	0.971399304	-0.045670505	normal	0.916774373	-0.377978258	normal	0.943677946	-0.256411711	normal	0.627811815	-0.235886562	normal	--	--	--	--	--	--	--	Ciliary protein causing Leber congenital amaurosis disease	Lebercilin GN=LCA5 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: lebercilin [Odobenus rosmarus divergens]
ENSG00000135341(MAP3K7)	--	11.42074079	878	12.21996233	940	12.15808215	937	11.746908	933	12.2893653	979	10.20449159	828	0.977121271	0.056727576	normal	0.978074066	0.03716296	normal	0.959980576	-0.186389485	normal	0.925424233	-0.029318228	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04427|0|umr:103660092|MAP3K7; mitogen-activated protein kinase kinase kinase 7; K04427 mitogen-activated protein kinase kinase kinase 7 [EC:2.7.11.25] (A)	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; AMPK signaling pathway (ko04152);; Wnt signaling pathway (ko04310);; Osteoclast differentiation (ko04380);; Adherens junction (ko04520);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; T cell receptor signaling pathway (ko04660);; TNF signaling pathway (ko04668);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Measles (ko05162);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Mitogen-activated protein kinase kinase kinase 7 GN=MAP3K7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 7 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000135362(PRR5L)	--	1.380795975	62	1.466177295	63	2.63455384	80	6.905897229	263	6.410104502	281	6.617118436	241	1.18E-14	2.027439725	up	4.44E-16	2.109549638	up	4.60E-09	1.564779702	up	1.38E-13	1.916137738	up	--	--	--	--	--	--	--	HbrB-like	Proline-rich protein 5-like GN=PRR5L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: proline-rich protein 5-like isoform X1 [Ochotona princeps]
ENSG00000135363(LMO2)	--	0.037239678	1	0.107418381	3	0	0	0.183398747	5	0.284706	9	0.110642059	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K15612|3.01848e-118|pon:100459801|LMO2; LIM domain only 2 (rhombotin-like 1); K15612 rhombotin-2 (A)	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	LIM domain	Rhombotin-2 GN=LMO2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: rhombotin-2 [Elephantulus edwardii]
ENSG00000135365(PHF21A)	--	10.19780406	1025	14.82937567	1074	12.85686586	918	10.34469547	844	7.923724101	659	8.995189297	849	0.888874084	-0.31062717	normal	0.0050348	-0.724753666	normal	0.971815356	-0.120814027	normal	0.023568377	-0.380754964	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[R]	General function prediction only	PHD-finger;; AT hook motif	PHD finger protein 21A GN=PHF21A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: PHD finger protein 21A isoform X3 [Loxodonta africana]
ENSG00000135372(NAT10)	--	21.36209317	1716	22.8417299	1795	22.68329742	1809	24.016138	1911	22.2488691	1759	20.66617574	1644	0.981028566	0.124340436	normal	0.984676483	-0.050611843	normal	0.978117222	-0.146145338	normal	0.940617376	-0.02323379	normal	[R]	General function prediction only	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	K14521|0|pps:100994927|NAT10; N-acetyltransferase 10 (GCN5-related); K14521 N-acetyltransferase 10 [EC:2.3.1.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	GNAT acetyltransferase 2;; Helicase;; Domain of unknown function (DUF1726);; Possible tRNA binding domain;; Acetyltransferase (GNAT) family	N-acetyltransferase 10 GN=NAT10 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: N-acetyltransferase 10 [Capra hircus]
ENSG00000135373(EHF)	--	0.628276957	47	0.666109446	30	0.77065949	36	7.491987032	506	14.50296809	905	7.519006754	635	0	3.35607262	up	0	4.8254456	up	0	4.076638728	up	2.64E-12	4.15802467	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K17102|0|pps:100992280|EHF; ets homologous factor; K17102 ETS homologous factor (A)	--	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	ETS homologous factor OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: ETS homologous factor isoform X3 [Capra hircus]
ENSG00000135374(ELF5)	--	0.095653207	3	0	0	0.063662316	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K17101|0|ptr:739906|ELF5; E74-like factor 5 (ets domain transcription factor); K17101 E74-like factor 5 (A)	Prolactin signaling pathway (ko04917)	[K]	Transcription	Sterile alpha motif (SAM)/Pointed domain;; Ets-domain	ETS-related transcription factor Elf-5 GN=ELF5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS-related transcription factor Elf-5 isoform X3 [Myotis brandtii]
ENSG00000135378(PRRG4)	--	0.30683106	26	0.349692256	29	0.533676	44	1.639322291	141	2.163214	184	1.395245	118	5.72E-12	2.342109464	up	2.22E-16	2.583244241	up	0.000237996	1.384729705	up	1.49E-08	2.141205432	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain	Transmembrane gamma-carboxyglutamic acid protein 4 (Precursor) GN=PRRG4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: transmembrane gamma-carboxyglutamic acid protein 4 [Ursus maritimus]
ENSG00000135387(CAPRIN1)	--	93.10948155	7240	89.83311067	6895	95.62030285	7270	107.3439392	8339	109.8339729	8502	89.327454	6885	0.991391908	0.173018196	normal	0.976243555	0.280769606	normal	0.994159107	-0.086771601	normal	0.575166093	0.126891596	normal	--	--	--	"K18743|0|hsa:4076|CAPRIN1, GPIAP1, GPIP137, GRIP137, M11S1, RNG105, p137GPI; cell cycle associated protein 1; K18743 caprin-1 (A)"	--	--	--	Cytoplasmic activation/proliferation-associated protein-1 C term	Caprin-1 GN=CAPRIN1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caprin-1 isoform 2 [Canis lupus familiaris]
ENSG00000135390(ATP5G2)	--	405.8343843	2719	398.931791	2646	399.1656069	2691	400.2571866	2727	408.4474388	2719	391.9354816	2661	0.989354075	-0.026578718	normal	0.98901066	0.017826481	normal	0.989232714	-0.024451504	normal	0.971851655	-0.012138762	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting two-sector ATPase complex, proton-transporting domain (GO:0033177);; "	"K02128|4.0993e-104|pps:100980736|ATP5G2; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9); K02128 F-type H+-transporting ATPase subunit c (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	ATP synthase subunit C	"ATP synthase F(0) complex subunit C2, mitochondrial (Precursor) GN=ATP5G2 OS=Homo sapiens (Human) PE=2 SV=1"	C	Energy production and conversion	"PREDICTED: LOW QUALITY PROTEIN: ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9) [Equus caballus]"
ENSG00000135392(DNAJC14)	--	61.17765703	1774	68.74112561	1861	59.6567667	1665	74.78772958	2094	79.94596219	2053	70.62493444	1842	0.968809589	0.208257014	normal	0.98201948	0.120136042	normal	0.979339745	0.137340798	normal	0.430205206	0.154608838	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09534|0|hsa:85406|DNAJC14, DNAJ, DRIP78, HDJ3, LIP6; DnaJ (Hsp40) homolog, subfamily C, member 14; K09534 DnaJ homolog subfamily C member 14 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cleavage inducing molecular chaperone;; DnaJ domain	DnaJ homolog subfamily C member 14 GN=DNAJC14 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 14 isoform X1 [Galeopterus variegatus]
ENSG00000135404(CD63)	--	387.001757	5155	469.6169814	6279	421.4589979	5758	639.912948	8677	565.456425	7401	727.2025893	9775	0.003890439	0.720224463	normal	0.986391174	0.215710949	normal	0.001427476	0.755083522	normal	0.002344647	0.567665267	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06497|8.80021e-145|mcf:102132387|CD63; CD63 molecule; K06497 CD63 antigen (A)	Lysosome (ko04142);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	Tetraspanin family	CD63 antigen GN=CD63 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: CD63 antigen [Panthera tigris altaica]
ENSG00000135406(PRPH)	--	0.35203067	21	0.333639233	18	0.238411112	14	0.397913606	15	0.276098504	16	0.374191329	16	0.983847336	-0.474959298	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07607|0|hsa:5630|PRPH, NEF4, PRPH1; peripherin; K07607 peripherin (A)"	Amyotrophic lateral sclerosis (ALS) (ko05014)	--	--	Intermediate filament protein;; Intermediate filament head (DNA binding) region	Peripherin GN=PRPH OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: peripherin [Mustela putorius furo] 
ENSG00000135407(AVIL)	--	0.0641253	3	0.211194	14	0.1912987	5	0.1937027	9	0.149201	9	0.167232	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	"K08017|0|hsa:10677|AVIL, ADVIL, DOC6, p92; advillin; K08017 advillin (A)"	--	[Z]	Cytoskeleton	Gelsolin repeat;; Villin headpiece domain	Advillin GN=AVIL OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: advillin isoform 1 [Equus caballus]
ENSG00000135409(AMHR2)	--	0.277913622	6	0.165120049	3	0.824378562	15	0.817797274	16	0.379551053	6	0.454763373	9	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	K04672|0|ggo:101149682|AMHR2; anti-Muellerian hormone type-2 receptor isoform 1; K04672 anti-mullerian hormone receptor type-2 [EC:2.7.11.30] (A)	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Activin types I and II receptor domain	Anti-Muellerian hormone type-2 receptor (Precursor) GN=AMHR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: anti-Muellerian hormone type-2 receptor isoform X1 [Galeopterus variegatus]
ENSG00000135414(GDF11)	--	4.14064	466	3.423451	337	3.848647	404	6.014199	665	4.535465	514	5.71988	538	0.452413662	0.480858833	normal	0.169743708	0.585451339	normal	0.726361946	0.403645826	normal	0.027682729	0.486603908	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K05497|0|ocu:100341680|GDF11; growth differentiation factor 11; K05497 growth differentiation factor 8/11 (A)	--	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Growth/differentiation factor 11 (Precursor) GN=GDF11 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: growth/differentiation factor 11 [Oryctolagus cuniculus]
ENSG00000135423(GLS2)	--	0.101185706	5	0.194332948	8	0.234429497	9	0.098153014	4	0.095625028	3	0.12173092	5	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: glutaminase activity (GO:0004359);; Molecular Function: protein binding (GO:0005515);; Biological Process: glutamine metabolic process (GO:0006541);; 	"K01425|0|pps:100969815|GLS2; glutaminase 2 (liver, mitochondrial); K01425 glutaminase [EC:3.5.1.2] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; D-Glutamine and D-glutamate metabolism (ko00471);; Glutamatergic synapse (ko04724);; GABAergic synapse (ko04727);; Proximal tubule bicarbonate reclamation (ko04964);; MicroRNAs in cancer (ko05206);; Central carbon metabolism in cancer (ko05230)"	[E]	Amino acid transport and metabolism	Glutaminase;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	"Glutaminase liver isoform, mitochondrial (Precursor) GN=GLS2 OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: glutaminase liver isoform, mitochondrial [Tupaia chinensis]"
ENSG00000135424(ITGA7)	--	0.625459064	37	0.370208974	18	0.3001367	23	0.532130681	40	0.75684523	59	0.675690373	45	0.98192312	0.078506784	normal	0.006577787	1.612516773	up	0.765297701	0.916205877	normal	0.121041616	0.863671145	normal	--	--	--	"K06583|0|hsa:3679|ITGA7; integrin, alpha 7; K06583 integrin alpha 7 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Integrin alpha-7 70 kDa form (Precursor) GN=ITGA7 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: integrin alpha-7 isoform X1 [Equus przewalskii]
ENSG00000135436(FAM186B)	--	0.2985047	29	0.133486	13	0.353792346	24	0.31251482	16	0.3011473	17	0.2912762	27	0.93595565	-0.828880965	normal	--	--	--	0.985576284	0.152565717	normal	0.895327936	-0.15672365	normal	--	--	--	--	--	--	--	--	Protein FAM186B GN=FAM186B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM186B [Ceratotherium simum simum]
ENSG00000135437(RDH5)	--	82.6753453	732	84.03243787	798	72.00828489	667	67.48865855	651	69.25940144	616	81.67881142	737	0.952077338	-0.199573834	normal	0.742156117	-0.394032418	normal	0.966716661	0.135394273	normal	0.51010041	-0.153760084	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00061|0|hsa:5959|RDH5, 9cRDH, HSD17B9, RDH1, SDR9C5; retinol dehydrogenase 5 (11-cis/9-cis) (EC:1.1.1.315); K00061 11-cis-retinol dehydrogenase [EC:1.1.1.315] (A)"	Retinol metabolism (ko00830)	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	short chain dehydrogenase	11-cis retinol dehydrogenase (Precursor) GN=RDH5 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 11-cis retinol dehydrogenase [Physeter catodon]
ENSG00000135439(AGAP2)	--	0.9907952	87	0.312848153	29	0.351530244	39	0.575343463	47	0.949623645	81	0.38194239	37	0.271796039	-0.897279333	normal	0.003720783	1.414519408	up	0.981661479	-0.081014624	normal	0.971576238	0.068388151	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; 	"K17848|0|hsa:116986|AGAP2, CENTG1, GGAP2, PIKE; ArfGAP with GTPase domain, ankyrin repeat and PH domain 2; K17848 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (A)"	FoxO signaling pathway (ko04068);; Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Miro-like protein;; Ras family;; Ankyrin repeats (3 copies);; Ankyrin repeat;; PH domain;; Ankyrin repeats (many copies)	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 GN=AGAP2 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2-like isoform X1 [Chrysochloris asiatica]"
ENSG00000135443(KRT85)	--	0	0	0	0	0	0	0.0767201	2	0	0	0.021395676	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|pps:100973401|KRT85; keratin, type II cuticular Hb5; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cuticular Hb5 GN=KRT85 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: keratin, type II cuticular Hb5 [Oryctolagus cuniculus]"
ENSG00000135446(CDK4)	--	73.319347	2369	85.9592064	2768	83.49473289	2757	114.7803164	3627	106.9147944	3410	104.6668843	3470	0.092600722	0.583358436	normal	0.95538994	0.279363514	normal	0.924805739	0.323386508	normal	0.010692121	0.391277529	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02089|0|pps:100976294|CDK4; cyclin-dependent kinase 4; K02089 cyclin-dependent kinase 4 [EC:2.7.11.22] (A)	Cell cycle (ko04110);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Tight junction (ko04530);; T cell receptor signaling pathway (ko04660);; Hepatitis B (ko05161);; Measles (ko05162);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Pancreatic cancer (ko05212);; Glioma (ko05214);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Cyclin-dependent kinase 4 GN=CDK4 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	cyclin-dependent kinase 4 [Sus scrofa] 
ENSG00000135447(PPP1R1A)	--	0	0	0.0261382	1	0	0	0.0311898	1	0.079483646	2	0.0311028	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein phosphatase inhibitor activity (GO:0004864);; Biological Process: signal transduction (GO:0007165);; 	"K08050|4.3597e-106|hsa:5502|PPP1R1A, I1, IPP1; protein phosphatase 1, regulatory (inhibitor) subunit 1A (EC:3.1.3.16); K08050 protein phosphatase 1 regulatory subunit 1A (A)"	Adrenergic signaling in cardiomyocytes (ko04261);; Long-term potentiation (ko04720)	--	--	Protein phosphatase inhibitor 1/DARPP-32	Protein phosphatase 1 regulatory subunit 1A GN=PPP1R1A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	protein phosphatase 1 regulatory subunit 1A [Canis lupus familiaris] 
ENSG00000135451(TROAP)	--	22.05942317	485	25.79724558	528	22.06978938	494	23.35214667	478	25.61476833	537	23.87663727	571	0.970167329	-0.051641599	normal	0.971715543	0.002949225	normal	0.948650077	0.200117985	normal	0.876382372	0.053015462	normal	--	--	--	--	--	--	--	--	Tastin GN=TROAP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: tastin [Galeopterus variegatus]
ENSG00000135452(TSPAN31)	--	14.9543398	357	14.38076961	316	13.140095	329	14.70772257	383	16.70149208	402	15.588902	381	0.966844825	0.070295947	normal	0.872798233	0.324464798	normal	0.945216726	0.202546101	normal	0.482291886	0.197496177	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17356|9.28158e-124|ptr:746219|TSPAN31; tetraspanin 31; K17356 tetraspanin-13/31 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-31 GN=TSPAN31 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetraspanin-31 isoform X1 [Equus przewalskii]
ENSG00000135454(B4GALNT1)	--	34.02629984	2044	35.84901503	2098	33.92417309	2040	25.30557073	1408	24.94228413	1342	24.6316837	1431	0.111325598	-0.56806233	normal	0.01533461	-0.665451497	normal	0.261270707	-0.519374731	normal	3.83E-05	-0.585419852	normal	--	--	--	"K00725|0|pps:100977739|B4GALNT1; beta-1,4-N-acetyl-galactosaminyl transferase 1; K00725 (N-Acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase [EC:2.4.1.92] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	--	--	Glycosyl transferase family 2	"Beta-1,4 N-acetylgalactosaminyltransferase 1 GN=B4GALNT1 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: beta-1,4 N-acetylgalactosaminyltransferase 1 isoform X2 [Galeopterus variegatus]"
ENSG00000135457(TFCP2)	--	10.9850841	671	10.3048797	615	10.1729525	631	10.86474801	675	10.61738923	644	10.72380685	633	0.974737862	-0.022206831	normal	0.972724734	0.044939728	normal	0.974329076	-0.003717053	normal	0.992544847	0.004698038	normal	--	--	--	K09275|0|ptr:450171|TFCP2; transcription factor CP2; K09275 transcription factor CP2 and related proteins (A)	--	[K]	Transcription	CP2 transcription factor	Alpha-globin transcription factor CP2 GN=TFCP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: alpha-globin transcription factor CP2 isoform X1 [Camelus ferus] 
ENSG00000135469(COQ10A)	--	14.34546096	335	18.10293933	431	16.4902061	382	16.93488151	388	17.35298478	399	21.28705414	492	0.951121828	0.180294466	normal	0.9605065	-0.132243263	normal	0.826419235	0.355550812	normal	0.647743816	0.135349059	normal	[I]	Lipid transport and metabolism	--	"K18588|1.04377e-164|ggo:101145761|COQ10A; coenzyme Q-binding protein COQ10 homolog A, mitochondrial isoform 1; K18588 coenzyme Q-binding protein COQ10 (A)"	--	[I]	Lipid transport and metabolism	Polyketide cyclase / dehydrase and lipid transport	"Coenzyme Q-binding protein COQ10 homolog A, mitochondrial (Precursor) GN=COQ10A OS=Homo sapiens (Human) PE=2 SV=2"	I	Lipid transport and metabolism	"PREDICTED: coenzyme Q-binding protein COQ10 homolog A, mitochondrial isoform X1 [Felis catus]"
ENSG00000135476(ESPL1)	--	12.52580172	1377	11.71446	1326	10.90429027	1391	12.0204406	1440	9.411669017	1208	11.9742951	1541	0.983017433	0.03367125	normal	0.971866671	-0.155700747	normal	0.976669334	0.139309048	normal	0.972791873	0.012090174	normal	--	--	--	"K02365|0|hsa:9700|ESPL1, ESP1, SEPA; extra spindle pole bodies homolog 1 (S. cerevisiae) (EC:3.4.22.49); K02365 separase [EC:3.4.22.49] (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Peptidase family C50	Separin GN=ESPL1 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: separin [Ceratotherium simum simum]
ENSG00000135480(KRT7)	--	1029.530156	36850	953.27348	34654	1074.96772	39466	1403.210398	50416	1449.767616	51700	1009.760362	36145	0.953656289	0.421369703	normal	0.589358041	0.555695859	normal	0.998183602	-0.135100245	normal	0.245054704	0.295376665	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:3855|KRT7, CK7, K2C7, K7, SCL; keratin 7; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 7 GN=KRT7 OS=Homo sapiens (Human) PE=1 SV=5"	Z	Cytoskeleton	"PREDICTED: keratin, type II cytoskeletal 7 [Mustela putorius furo] "
ENSG00000135482(ZC3H10)	--	37.73754112	3257	38.535304	3321	38.91499517	3424	44.46470501	3782	42.25028022	3448	35.157717	2962	0.982675838	0.184692475	normal	0.990616042	0.03270088	normal	0.975833055	-0.217299217	normal	0.986272296	0.005305992	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[K]	Transcription	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 10 GN=ZC3H10 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger CCCH domain-containing protein 10 isoform X1 [Canis lupus familiaris] 
ENSG00000135486(HNRNPA1)	--	690.6251833	18899	682.9582277	19141	675.1013657	18594	913.8503388	24572	889.496163	23904	818.6746351	22505	0.974661292	0.347848265	normal	0.986911214	0.299138105	normal	0.990568198	0.267097188	normal	0.126497932	0.304277557	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12741|5.60872e-138|umr:103675559|HNRNPA1; heterogeneous nuclear ribonucleoprotein A1; K12741 heterogeneous nuclear ribonucleoprotein A1/A3 (A)	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed GN=HNRNPA1 OS=Homo sapiens (Human) PE=1 SV=5"	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein A1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000135502(SLC26A10)	--	1.86994	78	1.5299	66	1.78867	77	1.14228	48	1.02735	42	1.13932	48	0.700721513	-0.71318173	normal	0.830415356	-0.65454148	normal	0.763099167	-0.67321681	normal	0.140541676	-0.700471925	normal	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14707|0|hsa:65012|SLC26A10; solute carrier family 26, member 10; K14707 solute carrier family 26, member 10 (A)"	--	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain	Solute carrier family 26 member 10 GN=SLC26A10 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 26 member 10 [Galeopterus variegatus]
ENSG00000135503(ACVR1B)	--	10.35414506	811	8.993215516	729	9.190430432	664	9.94096713	802	10.0571134	787	10.23802707	813	0.976152274	-0.0468427	normal	0.97237908	0.088840863	normal	0.910099841	0.283196835	normal	0.683873009	0.102721828	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K13567|0|ptr:451911|ACVR1B; activin A receptor, type IB; K13567 activin receptor type-1B [EC:2.7.11.30] (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Transforming growth factor beta type I GS-motif;; Activin types I and II receptor domain	Activin receptor type-1B (Precursor) GN=ACVR1B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: activin receptor type-1B isoform X1 [Orycteropus afer afer]
ENSG00000135506(OS9)	--	55.95113795	3481	51.59771588	3306	49.64514067	3132	53.75616178	3359	57.22081545	3515	61.17785513	3776	0.989859079	-0.082265314	normal	0.990016961	0.06698169	normal	0.965141385	0.261368016	normal	0.728697096	0.081623363	normal	--	--	--	"K10088|0|pps:100974599|OS9; osteosarcoma amplified 9, endoplasmic reticulum lectin; K10088 protein OS-9 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[R]	General function prediction only	Glucosidase II beta subunit-like protein	Protein OS-9 (Precursor) GN=OS9 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein OS-9 isoform X2 [Galeopterus variegatus]
ENSG00000135519(KCNH3)	--	5.96017	433	2.63513	195	3.91808	294	1.78608	129	2.241274	162	1.202965	88	2.89E-15	-1.765620575	down	0.922096682	-0.286465497	normal	3.74E-12	-1.731260652	down	0.041966434	-1.304488474	normal	[T]	Signal transduction mechanisms	"Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; "	"K04906|0|hsa:23416|KCNH3, BEC1, ELK2, Kv12.2; potassium voltage-gated channel, subfamily H (eag-related), member 3; K04906 potassium voltage-gated channel Eag-related subfamily H member 3 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PAS domain;; Ion transport protein;; Ion channel;; Cyclic nucleotide-binding domain;; PAS fold;; PAS fold	Potassium voltage-gated channel subfamily H member 3 GN=KCNH3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily H member 3 isoform X2 [Tupaia chinensis]
ENSG00000135521(LTV1)	--	16.964194	666	16.697283	662	18.34499	721	16.525093	657	19.326825	750	13.95122	547	0.973664509	-0.050344133	normal	0.962275614	0.158292927	normal	0.704773871	-0.405769518	normal	0.740304548	-0.089926493	normal	--	--	--	K14798|0|pon:100190824|LTV1; LTV1 ribosome biogenesis factor; K14798 protein LTV1 (A)	--	[S]	Function unknown	Low temperature viability protein	Protein LTV1 homolog GN=LTV1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein LTV1 homolog isoform X2 [Galeopterus variegatus]
ENSG00000135525(MAP7)	--	11.41981235	965	13.13715585	1143	12.23684709	1034	24.1846284	2071	28.37842784	2408	31.547751	2703	2.88E-08	1.069705076	up	7.93E-08	1.052602526	up	2.18E-14	1.376740709	up	1.56E-10	1.172258836	up	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: microtubule cytoskeleton (GO:0015630);; 	K10433|0|pps:100991347|MAP7; microtubule-associated protein 7; K10433 microtubule-associated protein 7 (A)	--	--	--	MAP7 (E-MAP-115) family	Ensconsin GN=MAP7 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: ensconsin isoform X1 [Pteropus alecto]
ENSG00000135535(CD164)	--	84.78217562	3094	87.45457611	3162	77.70249	2757	85.08501086	3120	79.804395	2912	87.7581447	3228	0.990425256	-0.018750159	normal	0.985362959	-0.14018368	normal	0.974314452	0.219138674	normal	0.95613985	0.017659169	normal	--	--	--	"K06546|3.89952e-98|ptr:462926|CD164; CD164 molecule, sialomucin; K06546 CD164 antigen (A)"	Lysosome (ko04142)	--	--	Multi-glycosylated core protein 24 (MGC-24)	Sialomucin core protein 24 (Precursor) GN=CD164 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sialomucin core protein 24 [Tupaia chinensis]
ENSG00000135537(LACE1)	--	1.053432073	71	1.590302775	81	1.720914217	87	1.759078992	97	0.88440729	72	1.384494905	75	0.917050236	0.411685862	normal	0.965551137	-0.187633379	normal	0.963019247	-0.218324958	normal	1	0.00799428	normal	[R]	General function prediction only	Molecular Function: ATP binding (GO:0005524);; 	"K18798|0|hsa:246269|LACE1, AFG1; lactation elevated 1; K18798 protein AFG1 (A)"	--	[R]	General function prediction only	AFG1-like ATPase;; ATPase family associated with various cellular activities (AAA)	Lactation elevated protein 1 GN=LACE1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: lactation elevated protein 1 [Panthera tigris altaica]
ENSG00000135540(NHSL1)	--	1.8917052	277	1.55560834	238	2.123812516	337	1.442278257	223	1.000811028	151	1.299749167	181	0.871089457	-0.341558176	normal	0.16750106	-0.672426869	normal	0.001263914	-0.899453173	normal	0.018999173	-0.639851473	normal	--	--	--	--	--	--	--	NHS-like	NHS-like protein 1 GN=NHSL1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: NHS-like protein 1 isoform X2 [Mustela putorius furo] 
ENSG00000135541(AHI1)	--	8.86237978	681	9.09014614	700	10.86126589	641	6.686113507	560	5.69383527	625	6.949140201	712	0.879498049	-0.312281788	normal	0.955448857	-0.184503172	normal	0.965033917	0.142941332	normal	0.660561833	-0.112659585	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K16740|0|hsa:54806|AHI1, AHI-1, JBTS3, ORF1, dJ71N10.1; Abelson helper integration site 1; K16740 jouberin (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain"	Jouberin GN=AHI1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: jouberin [Galeopterus variegatus]
ENSG00000135547(HEY2)	--	0.026564408	1	0	0	0	0	0.026557753	1	0.025700936	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K09091|1.512e-159|pps:100986179|HEY2; hes-related family bHLH transcription factor with YRPW motif 2; K09091 hairy and enhancer of split related with YRPW motif (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain;; Hairy Orange	Hairy/enhancer-of-split related with YRPW motif protein 2 GN=HEY2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hairy/enhancer-of-split related with YRPW motif protein 2 [Vicugna pacos] 
ENSG00000135549(PKIB)	--	3.850710056	92	4.061637811	95	3.842200173	92	6.428646	155	5.684447767	140	10.13359889	245	0.277096577	0.712470152	normal	0.738748594	0.53099858	normal	2.22E-07	1.390232734	up	0.044280079	0.932835303	normal	--	--	--	--	--	--	--	cAMP-dependent protein kinase inhibitor	cAMP-dependent protein kinase inhibitor beta GN=PKIB OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: cAMP-dependent protein kinase inhibitor beta [Galeopterus variegatus]
ENSG00000135587(SMPD2)	--	5.966721	171	6.316759	186	7.32231	193	4.41209	130	6.637538	176	6.458047	174	0.838083138	-0.42195338	normal	0.962197812	-0.100315132	normal	0.957396779	-0.156512746	normal	0.579236144	-0.216542772	normal	--	--	--	"K12351|0|hsa:6610|SMPD2, ISC1, NSMASE, NSMASE1; sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (EC:3.1.4.12); K12351 sphingomyelin phosphodiesterase 2 [EC:3.1.4.12] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[T]	Signal transduction mechanisms	Endonuclease/Exonuclease/phosphatase family	Sphingomyelin phosphodiesterase 2 GN=SMPD2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: sphingomyelin phosphodiesterase 2 [Ceratotherium simum simum]
ENSG00000135597(REPS1)	--	11.30204558	627	10.407819	571	10.7269561	622	12.40822961	627	12.53539285	705	9.060845265	551	0.973741167	-0.030756896	normal	0.909258233	0.282032665	normal	0.954818141	-0.182681481	normal	0.93870179	0.027719186	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cytoskeletal-regulatory complex EF hand	RalBP1-associated Eps domain-containing protein 1 GN=REPS1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ralBP1-associated Eps domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000135604(STX11)	--	0.794683513	27	0.78996347	27	0.686448402	23	0.293887652	10	0.338466641	11	0.408310391	14	0.720759353	-1.334554659	normal	0.801343047	-1.207802025	normal	0.972674163	-0.667725181	normal	0.083078847	-1.157962367	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K08487|0|hsa:8676|STX11, FHL4, HLH4, HPLH4; syntaxin 11; K08487 syntaxin 11 (A)"	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain;; Syntaxin	Syntaxin-11 GN=STX11 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-11 isoform X1 [Tupaia chinensis] 
ENSG00000135617(PRADC1)	--	10.424235	175	5.3554811	92	9.30108	161	12.11148623	220	11.638591	200	8.06679	140	0.915034596	0.29698677	normal	0.000613285	1.086467039	up	0.951408915	-0.207830035	normal	0.466248834	0.36584187	normal	--	--	--	--	--	[R]	General function prediction only	PA domain	Protease-associated domain-containing protein 1 (Precursor) GN=PRADC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protease-associated domain-containing protein 1 [Sus scrofa]
ENSG00000135622(SEMA4F)	--	13.31814572	885	13.679219	818	13.9033734	830	8.87250711	554	9.275696	509	8.146239	483	0.007986049	-0.705061258	normal	0.010987187	-0.704194946	normal	0.001224785	-0.78747529	normal	4.67E-06	-0.733950456	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06521|0|pps:100983489|SEMA4F; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F; K06521 semaphorin 4 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-4F (Precursor) GN=SEMA4F OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: semaphorin-4F isoform X1 [Equus caballus]
ENSG00000135624(CCT7)	--	283.597204	10313	278.063946	10321	299.526399	10995	224.4603784	8202	206.166985	7354	189.450361	6830	0.940291172	-0.361188187	normal	0.528147284	-0.510319192	normal	0.009253649	-0.69505909	normal	0.001064456	-0.520293538	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09499|0|pps:100994200|CCT7; chaperonin containing TCP1, subunit 7 (eta); K09499 T-complex protein 1 subunit eta (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit eta GN=CCT7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: T-complex protein 1 subunit eta [Pteropus alecto]
ENSG00000135631(RAB11FIP5)	--	25.32557747	2352	25.1357587	2282	25.64782613	2454	25.89515586	2380	25.16782175	2304	20.58000323	1824	0.988318117	-0.013749821	normal	0.987755127	-0.007579634	normal	0.642525848	-0.436008117	normal	0.47437796	-0.144975904	normal	--	--	--	K12484|0|ggo:101129368|RAB11FIP5; rab11 family-interacting protein 5 isoform 1; K12484 Rab11 family-interacting protein 1/2/5 (A)	Endocytosis (ko04144)	--	--	FIP domain;; C2 domain	Rab11 family-interacting protein 5 GN=RAB11FIP5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	Rab11 family-interacting protein 5 [Pteropus alecto]
ENSG00000135632(SMYD5)	--	22.68182216	1200	22.49171745	1207	21.64591817	1162	14.63912186	777	16.20372091	846	17.19742587	913	0.018483298	-0.656826032	normal	0.230472516	-0.533319986	normal	0.827029337	-0.355691185	normal	0.000798268	-0.513721299	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[B]	Chromatin structure and dynamics	SET domain	SET and MYND domain-containing protein 5 GN=SMYD5 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: SET and MYND domain-containing protein 5 [Oryctolagus cuniculus]
ENSG00000135636(DYSF)	--	0.147871826	23	0.19208481	30	0.286587189	45	1.765378135	275	1.110559263	172	2.194012262	343	0	3.464688649	up	1.39E-14	2.440232373	up	0	2.880733166	up	8.74E-07	2.991313279	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K18261|0|pps:100987146|DYSF; dysferlin; K18261 dysferlin (A)	--	[M]	Cell wall/membrane/envelope biogenesis	C2 domain;; FerB (NUC096) domain;; FerI (NUC094) domain;; FerA (NUC095) domain;; Integral peroxisomal membrane peroxin	Dysferlin GN=DYSF OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: dysferlin isoform X1 [Orycteropus afer afer]
ENSG00000135637(CCDC142)	--	3.996376	252	4.334953001	285	4.47958	278	2.492960887	161	3.57272	216	3.195856	200	0.142317996	-0.67202291	normal	0.765640443	-0.418795633	normal	0.632362033	-0.480281792	normal	0.044686608	-0.518664957	normal	--	--	--	--	--	--	--	Coiled-coil protein 142	Coiled-coil domain-containing protein 142 GN=CCDC142 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 142 [Galeopterus variegatus]
ENSG00000135638(EMX1)	--	0.105689	3	0	0	0	0	0	0	0	0	0.036851884	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09317|1.34544e-151|hsa:2016|EMX1; empty spiracles homeobox 1; K09317 homeobox protein EMX (A)	--	[K]	Transcription	Homeobox domain	Homeobox protein EMX1 GN=EMX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein EMX1 [Lipotes vexillifer]
ENSG00000135643(KCNMB4)	--	0.927058	68	0.880911079	65	0.648683903	47	1.122407	83	1.573441112	116	1.1373608	84	0.961435055	0.251592558	normal	0.266393098	0.800073707	normal	0.483825069	0.809692631	normal	0.14533625	0.631253407	normal	--	--	Biological Process: potassium ion transport (GO:0006813);; Molecular Function: calcium-activated potassium channel activity (GO:0015269);; Cellular Component: membrane (GO:0016020);; 	"K04941|1.43693e-143|ptr:742962|KCNMB4; potassium large conductance calcium-activated channel, subfamily M, beta member 4; K04941 potassium large conductance calcium-activated channel subfamily M beta member 4 (A)"	cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Insulin secretion (ko04911)	--	--	"Calcium-activated potassium channel, beta subunit"	Calcium-activated potassium channel subunit beta-4 GN=KCNMB4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: calcium-activated potassium channel subunit beta-4 [Ochotona princeps]
ENSG00000135655(USP15)	--	12.04675088	906	11.71343008	823	12.57896062	876	15.14506835	1132	13.63366074	1026	11.89333183	880	0.911532112	0.290018011	normal	0.905203925	0.296151606	normal	0.978111133	-0.001715833	normal	0.312120945	0.199946965	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11835|0|mcf:101865179|Ubiquitin carboxyl-terminal hydrolase 15; K11835 ubiquitin carboxyl-terminal hydrolase 4/11/15 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin-like domain;; Ubiquitin carboxyl-terminal hydrolase;; DUSP domain;; Ubiquitin-specific protease C-terminal	Ubiquitin carboxyl-terminal hydrolase 15 GN=USP15 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 15 isoform X1 [Camelus ferus] 
ENSG00000135677(GNS)	--	62.29370697	5415	59.95620997	5189	56.95194647	4818	62.65272682	5449	61.51951842	5329	70.41021569	6119	0.993798188	-0.021795946	normal	0.993427537	0.016976857	normal	0.938110115	0.336476135	normal	0.624874209	0.110756655	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	K01137|0|ptr:467054|GNS; glucosamine (N-acetyl)-6-sulfatase; K01137 N-acetylglucosamine-6-sulfatase [EC:3.1.6.14] (A)	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	Sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	N-acetylglucosamine-6-sulfatase (Precursor) GN=GNS OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: N-acetylglucosamine-6-sulfatase [Tupaia chinensis]
ENSG00000135678(CPM)	--	11.034716	281	8.822079	129	32.73416496	222	53.5501328	780	106.4912706	879	57.450766	410	1.04E-12	1.437157939	up	0	2.732873455	up	0.001099269	0.872333204	normal	0.004671356	1.688613468	up	--	--	"Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Biological Process: metabolic process (GO:0008152);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	K01296|0|hsa:1368|CPM; carboxypeptidase M (EC:3.4.17.12); K01296 carboxypeptidase M [EC:3.4.17.12] (A)	--	[R]	General function prediction only	Zinc carboxypeptidase;; Carboxypeptidase regulatory-like domain;; Succinylglutamate desuccinylase / Aspartoacylase family	Carboxypeptidase M (Precursor) GN=CPM OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carboxypeptidase M isoform X2 [Galeopterus variegatus]
ENSG00000135679(MDM2)	--	23.69771155	2274	39.30516509	3708	27.53434664	2793	36.24398196	3731	40.6336325	3868	56.17239665	5599	0.008049958	0.683134137	normal	0.991300305	0.039504218	normal	2.45E-07	0.994674201	normal	0.17219571	0.568646437	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06643|0|ptr:742141|MDM2; MDM2 proto-oncogene, E3 ubiquitin protein ligase; K06643 E3 ubiquitin-protein ligase Mdm2 [EC:6.3.2.19] (A)"	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115);; Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Thyroid hormone signaling pathway (ko04919);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220)	--	--	"SWIB/MDM2 domain;; Zinc finger, C3HC4 type (RING finger);; Zn-finger in Ran binding protein and others;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase Mdm2 GN=MDM2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase Mdm2 isoform X2 [Galeopterus variegatus]
ENSG00000135686(KLHL36)	--	14.209409	1289	11.87851038	1255	13.83221789	1365	12.996417	1401	13.512092	1274	15.641043	1399	0.980113858	0.08927035	normal	0.981794061	0.000251055	normal	0.982982129	0.027173831	normal	0.891433938	0.038544362	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13958|0|hsa:79786|KLHL36, C16orf44; kelch-like family member 36; K13958 kelch-like protein 36 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 36 GN=KLHL36 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 36 isoformX1 [Canis lupus familiaris] 
ENSG00000135697(BCO1)	--	1.155924096	34	0.912394	43	1.276684698	51	2.8515091	127	3.1811769	125	3.550499849	171	1.66E-07	1.824823851	up	3.76E-05	1.486067426	up	1.87E-08	1.707836451	up	4.39E-07	1.704677913	up	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00515|0|hsa:53630|BCO1, BCDO, BCDO1, BCMO, BCMO1, BCO; beta-carotene oxygenase 1 (EC:1.14.99.36); K00515 beta-carotene 15,15'-monooxygenase [EC:1.14.99.36] (A)"	Retinol metabolism (ko00830)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Retinal pigment epithelial membrane protein	"Beta,beta-carotene 15,15'-monooxygenase OS=Homo sapiens (Human) PE=1 SV=1"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: beta,beta-carotene 15,15'-monooxygenase [Ceratotherium simum simum]"
ENSG00000135698(MPHOSPH6)	--	20.829825	342	19.992647	360	23.69946	361	24.4974	402	20.04186	305	21.14594	334	0.945441775	0.201531173	normal	0.921703697	-0.259428658	normal	0.961876055	-0.119919754	normal	0.895762911	-0.052005555	normal	--	--	--	"K12593|8.45789e-83|hsa:10200|MPHOSPH6, MPP, MPP-6, MPP6; M-phase phosphoprotein 6; K12593 M-phase phosphoprotein 6, animal type (A)"	RNA degradation (ko03018)	[D]	"Cell cycle control, cell division, chromosome partitioning"	M-phase phosphoprotein 6	M-phase phosphoprotein 6 GN=MPHOSPH6 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: M-phase phosphoprotein 6 [Myotis lucifugus]
ENSG00000135702(CHST5)	--	0.1284282	5	0.11874561	6	0.152364358	4	0.039903197	2	0.173704485	8	0.157236657	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K09670|0|hsa:23563|CHST5, I-GlcNAc-6-ST, I-GlcNAc6ST, glcNAc6ST-3, gn6st-3, hIGn6ST; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5; K09670 carbohydrate 6-sulfotransferase 5 [EC:2.8.2.-] (A)"	--	--	--	Sulfotransferase domain;; Sulfotransferase family	Carbohydrate sulfotransferase 5 GN=CHST5 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: carbohydrate sulfotransferase 6 [Condylura cristata]
ENSG00000135709(KIAA0513)	--	2.57402159	360	3.269575209	468	2.993530401	436	2.89849516	343	2.082579595	293	2.857662514	352	0.964050038	-0.100182484	normal	0.031846943	-0.694172124	normal	0.87900605	-0.31582255	normal	0.097071099	-0.376557301	normal	--	--	--	--	--	--	--	Myotubularin protein	Uncharacterized protein KIAA0513 GN=KIAA0513 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA0513 homolog [Tupaia chinensis]
ENSG00000135720(DYNC1LI2)	--	32.20763959	3243	34.3591465	3367	34.52010259	3342	36.38671204	3511	37.15901658	3547	33.06588024	3278	0.989703033	0.083682602	normal	0.990427103	0.053685557	normal	0.990679606	-0.036170794	normal	0.903400159	0.03326251	normal	--	--	--	"K10416|0|ngi:103744501|Dync1li2; dynein, cytoplasmic 1, light intermediate chain 2; K10416 dynein light intermediate chain 1, cytosolic (A)"	Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Salmonella infection (ko05132)	[N]	Cell motility	Dynein light intermediate chain (DLIC)	Cytoplasmic dynein 1 light intermediate chain 2 GN=DYNC1LI2 OS=Homo sapiens (Human) PE=1 SV=1	N	Cell motility	PREDICTED: cytoplasmic dynein 1 light intermediate chain 2 isoform X1 [Mustela putorius furo]
ENSG00000135722(FBXL8)	--	10.302276	217	8.742591496	210	8.728442631	194	7.37714923	170	6.520214	146	6.4005378	136	0.852622395	-0.379944509	normal	0.563577215	-0.541146468	normal	0.65545574	-0.515912523	normal	0.11553709	-0.480329365	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10274|0|hsa:55336|FBXL8, FBL8; F-box and leucine-rich repeat protein 8; K10274 F-box and leucine-rich repeat protein 8 (A)"	--	--	--	F-box-like;; F-box domain	F-box/LRR-repeat protein 8 GN=FBXL8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: F-box/LRR-repeat protein 8 [Equus caballus]
ENSG00000135723(FHOD1)	--	16.68558885	1375	13.92186	1155	16.82875	1414	18.34472582	1497	20.21921932	1653	11.38641491	939	0.98074513	0.09171211	normal	0.379417445	0.495222654	normal	0.063423702	-0.598085922	normal	0.962333677	0.030049435	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain	FH1/FH2 domain-containing protein 1 GN=FHOD1 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: FH1/FH2 domain-containing protein 1 isoform X2 [Felis catus]
ENSG00000135736(CCDC102A)	--	5.665633261	277	6.667424923	341	5.855153385	303	5.353226	265	5.754321939	281	6.131372067	301	0.963517579	-0.094191649	normal	0.898061166	-0.299164035	normal	0.967781345	-0.017756829	normal	0.668518261	-0.141716455	normal	--	--	Molecular Function: motor activity (GO:0003774);; Cellular Component: myosin complex (GO:0016459);; 	K16759|0|hsa:92922|CCDC102A; coiled-coil domain containing 102A; K16759 coiled-coil domain-containing protein 102A (A)	--	--	--	--	Coiled-coil domain-containing protein 102A GN=CCDC102A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 102A [Odobenus rosmarus divergens]
ENSG00000135740(SLC9A5)	--	1.781184	105	1.324341	78	1.557888	89	1.376	76	1.591403	82	1.477699	82	0.858674887	-0.48870485	normal	0.97146397	0.049781855	normal	0.969342889	-0.124272277	normal	0.725058255	-0.201495851	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14723|0|hsa:6553|SLC9A5, NHE5; solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5; K14723 solute carrier family 9 (sodium/hydrogen exchanger), member 5 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 5 GN=SLC9A5 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 5 [Equus caballus]
ENSG00000135744(AGT)	--	0.0465221	2	0.068464	3	0.156594	6	0	0	0.0910331	3	0.41276	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K09821|0|hsa:183|AGT, ANHU, SERPINA8; angiotensinogen (serpin peptidase inhibitor, clade A, member 8); K09821 angiotensinogen (A)"	Renin-angiotensin system (ko04614)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Angiotensin 1-4 (Precursor) GN=AGT OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: angiotensinogen [Leptonychotes weddellii]
ENSG00000135749(PCNX2)	--	10.25149479	799	9.327920509	702	10.20015661	758	12.56326447	963	10.96146778	968	11.69692585	966	0.941458533	0.238090537	normal	0.594994613	0.441296742	normal	0.847112416	0.340929971	normal	0.052975186	0.337747004	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Pecanex protein (C-terminus)	Pecanex-like protein 2 GN=PCNXL2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: pecanex-like protein 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000135750(KCNK1)	--	11.80075655	329	10.96361636	274	12.13230122	338	14.24045731	405	12.125374	381	14.03905984	420	0.91680589	0.267872969	normal	0.647219224	0.452064028	normal	0.890868999	0.303852796	normal	0.159537845	0.337098794	normal	[P]	Inorganic ion transport and metabolism	--	"K04912|0|ptr:469712|KCNK1; potassium channel, subfamily K, member 1; K04912 potassium channel subfamily K member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 1 GN=KCNK1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	potassium channel subfamily K member 1 [Oryctolagus cuniculus] 
ENSG00000135763(URB2)	--	8.420146	878	8.23433	859	9.017004	933	8.959646	941	10.150151	1039	9.009836	852	0.976540645	0.069024837	normal	0.936211133	0.252634143	normal	0.969525394	-0.139079098	normal	0.813860466	0.063718178	normal	--	--	--	"K14862|0|hsa:9816|URB2, KIAA0133, NET10, NPA2; URB2 ribosome biogenesis 2 homolog (S. cerevisiae); K14862 nucleolar pre-ribosomal-associated protein 2 (A)"	--	--	--	Urb2/Npa2 family	Unhealthy ribosome biogenesis protein 2 homolog GN=URB2 OS=Homo sapiens (Human) PE=2 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: unhealthy ribosome biogenesis protein 2 homolog [Ceratotherium simum simum]
ENSG00000135766(EGLN1)	--	42.3271	2712	45.3628	2825	45.9277	2901	47.749	2992	44.3382	2962	54.6769	3510	0.987000477	0.110860925	normal	0.989215275	0.046869712	normal	0.961348656	0.266502812	normal	0.476894251	0.144896347	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K09592|0|hsa:54583|EGLN1, C1orf12, ECYT3, HALAH, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6; egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29); K09592 hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] (A)"	HIF-1 signaling pathway (ko04066);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	2OG-Fe(II) oxygenase superfamily;; MYND finger;; 2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily	Egl nine homolog 1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: egl nine homolog 1 [Tursiops truncatus]
ENSG00000135775(COG2)	--	11.63962761	622	10.78252458	574	11.78264915	623	12.09263568	649	13.03062321	696	10.55265318	564	0.973897431	0.030398126	normal	0.926455658	0.25599672	normal	0.961866471	-0.151441902	normal	0.880323281	0.048239209	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Domain of unknown function (DUF3510);; COG (conserved oligomeric Golgi) complex component, COG2"	Conserved oligomeric Golgi complex subunit 2 GN=COG2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: conserved oligomeric Golgi complex subunit 2 [Loxodonta africana]
ENSG00000135776(ABCB10)	--	12.749975	714	13.671487	776	12.35946	691	14.53031	821	11.65106	652	12.87677	720	0.961411031	0.170283978	normal	0.91834636	-0.272032042	normal	0.974488537	0.050910595	normal	0.973127428	-0.013922288	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05657|0|hsa:23456|ABCB10, EST20237, M-ABC2, MTABC2; ATP-binding cassette, sub-family B (MDR/TAP), member 10; K05657 ATP-binding cassette, subfamily B (MDR/TAP), member 10 (A)"	ABC transporters (ko02010)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ABC transporter transmembrane region;; ABC transporter;; AAA domain;; Predicted ATPase of the ABC class	"ATP-binding cassette sub-family B member 10, mitochondrial (Precursor) GN=ABCB10 OS=Homo sapiens (Human) PE=1 SV=2"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: ATP-binding cassette sub-family B member 10, mitochondrial, partial [Canis lupus familiaris]"
ENSG00000135778(NTPCR)	--	13.650732	1170	13.119591	1098	12.713353	1047	10.116259	941	11.435491	1029	14.468878	1271	0.846365094	-0.344568432	normal	0.974529029	-0.114898121	normal	0.929837597	0.271055283	normal	0.862636741	-0.052984046	normal	[F]	Nucleotide transport and metabolism	"Molecular Function: nucleotide phosphatase activity, acting on free nucleotides (GO:0098519);; "	"K06928|2.24273e-116|pps:100970719|NTPCR; nucleoside-triphosphatase, cancer-related; K06928 nucleoside-triphosphatase [EC:3.6.1.15] (A)"	Purine metabolism (ko00230);; Thiamine metabolism (ko00730)	--	--	NTPase;; AAA domain (dynein-related subfamily)	Cancer-related nucleoside-triphosphatase GN=NTPCR OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: cancer-related nucleoside-triphosphatase [Trichechus manatus latirostris]
ENSG00000135801(TAF5L)	--	9.087378	555	8.371592	527	9.018384964	572	9.7352917	618	11.270259	695	10.086127	619	0.965928403	0.123961505	normal	0.783247284	0.376839146	normal	0.968497792	0.105364976	normal	0.368620768	0.203126444	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03130|0|pps:100988287|TAF5L; TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; K03130 transcription initiation factor TFIID subunit 5 (A)"	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	"WD domain, G-beta repeat;; WD40 associated region in TFIID subunit;; Nucleoporin Nup120/160"	TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L GN=TAF5L OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L isoform X2 [Ursus maritimus]
ENSG00000135821(GLUL)	--	15.87981	1079	12.95303131	886	13.506476	922	7.759953209	528	10.61138185	718	8.122928769	555	1.74E-07	-1.059711414	down	0.871934697	-0.324133554	normal	0.003472842	-0.738991001	normal	0.000111676	-0.70174419	normal	[E]	Amino acid transport and metabolism	Molecular Function: glutamate-ammonia ligase activity (GO:0004356);; Biological Process: glutamine biosynthetic process (GO:0006542);; Biological Process: nitrogen compound metabolic process (GO:0006807);; 	K01915|0|pps:100975375|GLUL; glutamate-ammonia ligase; K01915 glutamine synthetase [EC:6.3.1.2] (A)	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; Glyoxylate and dicarboxylate metabolism (ko00630);; Nitrogen metabolism (ko00910);; Biosynthesis of amino acids (ko01230);; Glutamatergic synapse (ko04724);; GABAergic synapse (ko04727)"	[E]	Amino acid transport and metabolism	"Glutamine synthetase, catalytic domain;; Glutamine synthetase, beta-Grasp domain"	Glutamine synthetase GN=GLUL OS=Homo sapiens (Human) PE=1 SV=4	E	Amino acid transport and metabolism	PREDICTED: glutamine synthetase [Panthera tigris altaica]
ENSG00000135823(STX6)	--	14.241945	1154	15.433181	1270	14.789857	1197	16.605403	1360	15.191175	1223	15.26154	1238	0.96096053	0.205878462	normal	0.979633333	-0.075738738	normal	0.981286874	0.04024672	normal	0.830280218	0.056012689	normal	--	--	Cellular Component: membrane (GO:0016020);; Biological Process: Golgi vesicle transport (GO:0048193);; 	K08498|4.87347e-154|ptr:457561|STX6; syntaxin 6; K08498 syntaxin 6 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Syntaxin 6, N-terminal;; SNARE domain"	Syntaxin-6 GN=STX6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-6 [Camelus bactrianus] 
ENSG00000135828(RNASEL)	--	2.017874	166	2.21258	184	2.001745	165	1.984983983	165	2.010272	164	1.932666	159	0.966959498	-0.039185694	normal	0.95182927	-0.18581776	normal	0.966261761	-0.061159631	normal	0.839039608	-0.099108693	normal	[R]	General function prediction only	"Molecular Function: ribonuclease activity (GO:0004540);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: mRNA processing (GO:0006397);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K01165|0|hsa:6041|RNASEL, PRCA1, RNS4; ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) (EC:3.1.26.- 3.1.27.-); K01165 ribonuclease L (A)"	Hepatitis C (ko05160);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ribonuclease 2-5A;; Ankyrin repeats (many copies);; Ankyrin repeat;; Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	2-5A-dependent ribonuclease GN=RNASEL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: 2-5A-dependent ribonuclease [Galeopterus variegatus]
ENSG00000135829(DHX9)	--	67.77861	5694	73.10155	6178	74.4368	6189	76.25226	6425	73.01726	6090	59.216244	4966	0.991351653	0.143385261	normal	0.994006289	-0.042113817	normal	0.946861159	-0.325824434	normal	0.78986946	-0.068947844	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	K13184|0|pon:100449914|DHX9; DEAH (Asp-Glu-Ala-His) box helicase 9; K13184 ATP-dependent RNA helicase A [EC:3.6.4.13] (A)	--	[K]	Transcription	Double-stranded RNA binding motif;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; Oligonucleotide/oligosaccharide-binding (OB)-fold;; DEAD/DEAH box helicase	ATP-dependent RNA helicase A GN=DHX9 OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase A [Lipotes vexillifer]
ENSG00000135835(KIAA1614)	--	0.851534	101	0.822347752	81	0.4039718	68	0.3478631	51	0.978043179	77	0.87537686	78	0.069967616	-0.994896307	normal	0.97045741	-0.092714371	normal	0.968082096	0.185787402	normal	0.580427253	-0.299620351	normal	--	--	--	--	--	--	--	--	Uncharacterized protein KIAA1614 GN=KIAA1614 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein KIAA1614 homolog [Galeopterus variegatus]
ENSG00000135837(CEP350)	--	6.353348341	1594	7.289241231	1704	7.55170139	1723	8.834046273	1892	8.599708822	1865	7.442878869	1851	0.964593504	0.216236712	normal	0.981806255	0.108731478	normal	0.983119858	0.095010281	normal	0.500601368	0.13832364	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	"K16768|0|hsa:9857|CEP350, CAP350, GM133; centrosomal protein 350kDa; K16768 centrosomal protein CEP350 (A)"	--	[ZR]	Cytoskeleton;; General function prediction only	CAP-Gly domain	Centrosome-associated protein 350 GN=CEP350 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: centrosome-associated protein 350 [Ceratotherium simum simum]
ENSG00000135838(NPL)	--	1.500895886	51	1.439694275	54	1.529425003	55	1.100704871	42	1.551899282	60	2.050727603	78	0.97002847	-0.300932186	normal	0.973961741	0.127196158	normal	0.908023511	0.48451158	normal	0.845186733	0.150644668	normal	[EM]	Amino acid transport and metabolism;; Cell wall/membrane/envelope biogenesis	Biological Process: metabolic process (GO:0008152);; Molecular Function: lyase activity (GO:0016829);; 	K01639|0|pps:100978733|NPL; N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase); K01639 N-acetylneuraminate lyase [EC:4.1.3.3] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	--	--	Dihydrodipicolinate synthetase family	N-acetylneuraminate lyase GN=NPL OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: N-acetylneuraminate lyase isoform X2 [Equus caballus]
ENSG00000135842(FAM129A)	--	5.102152	643	5.95866	670	5.43881	616	1.5332267	205	1.830689	217	2.71686	338	4.44E-16	-1.672546232	down	2.33E-15	-1.641027668	down	0.000292278	-0.871266876	normal	2.89E-15	-1.363591613	down	--	--	--	--	--	--	--	--	Protein Niban GN=FAM129A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein Niban [Ceratotherium simum simum]
ENSG00000135845(PIGC)	--	23.719077	479	21.349357	443	26.553456	548	21.956704	456	24.735579	496	23.7085579	476	0.966183919	-0.101490387	normal	0.96025791	0.141151311	normal	0.944648304	-0.210880787	normal	0.848039481	-0.062511796	normal	--	--	Biological Process: GPI anchor biosynthetic process (GO:0006506);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: phosphatidylinositol N-acetylglucosaminyltransferase activity (GO:0017176);; 	"K03859|0|hsa:5279|PIGC, GPI2; phosphatidylinositol glycan anchor biosynthesis, class C (EC:2.4.1.198); K03859 phosphatidylinositol glycan, class C (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[I]	Lipid transport and metabolism	Phosphatidylinositol N-acetylglucosaminyltransferase	Phosphatidylinositol N-acetylglucosaminyltransferase subunit C GN=PIGC OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit C [Vicugna pacos]
ENSG00000135862(LAMC1)	--	66.70713968	9741	70.71623439	10004	68.33169611	9564	57.51704118	9170	61.176418	8538	62.22675939	8773	0.994763437	-0.117961234	normal	0.985191603	-0.249992496	normal	0.994141551	-0.132813369	normal	0.43379954	-0.167794746	normal	--	--	--	"K05635|0|hsa:3915|LAMC1, LAMB2; laminin, gamma 1 (formerly LAMB2); K05635 laminin, gamma 1 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Prion diseases (ko05020);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin N-terminal (Domain VI);; Laminin EGF-like (Domains III and V);; Laminin B (Domain IV)	Laminin subunit gamma-1 (Precursor) GN=LAMC1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	"PREDICTED: laminin subunit gamma-1, partial [Equus przewalskii]"
ENSG00000135870(RC3H1)	--	3.790270105	653	4.731346801	816	3.796544573	640	4.841285604	840	4.222252836	730	4.658606325	807	0.857308714	0.33178428	normal	0.958548468	-0.181742909	normal	0.86595531	0.325518885	normal	0.510489632	0.150923033	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K15690|0|ptr:457530|RC3H1; ring finger and CCCH-type domains 1; K15690 RING finger and CCCH-type zinc finger domain-containing protein (A)	--	--	--	"RING-type zinc-finger;; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Zinc finger, C3HC4 type (RING finger)"	Roquin-1 GN=RC3H1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: roquin-1 isoform X1 [Camelus ferus] 
ENSG00000135898(GPR55)	--	0	0	0	0	0.039182157	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08413|0|hsa:9290|GPR55, LPIR1; G protein-coupled receptor 55; K08413 G protein-coupled receptor 55 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 55 GN=GPR55 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 55 [Leptonychotes weddellii]
ENSG00000135899(SP110)	--	2.529168684	126	2.45959299	132	2.815285468	145	2.691728907	125	2.327160255	121	2.203357513	122	0.968575254	-0.041815962	normal	0.961131974	-0.145219037	normal	0.943920258	-0.254564978	normal	0.761082241	-0.15213972	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Sp100 domain;; SAND domain	Sp110 nuclear body protein GN=SP110 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: sp110 nuclear body protein [Ceratotherium simum simum]
ENSG00000135900(MRPL44)	--	28.75087	733	27.45017	723	31.87471	824	22.54562	601	22.61401	593	22.22336	586	0.875318941	-0.31654626	normal	0.887971976	-0.306680473	normal	0.358469185	-0.49894384	normal	0.037233018	-0.378189984	normal	--	--	--	"K17425|0|hsa:65080|MRPL44, COXPD16, L44MT, MRP-L44; mitochondrial ribosomal protein L44 (EC:3.1.26.-); K17425 large subunit ribosomal protein L44 [EC:3.1.26.-] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	--	"39S ribosomal protein L44, mitochondrial (Precursor) GN=MRPL44 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L44, mitochondrial [Canis lupus familiaris]"
ENSG00000135902(CHRND)	--	0.068892396	4	0.085016584	5	0	0	0	0	0	0	0.051175251	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04816|0|hsa:1144|CHRND, ACHRD, CMS2A, FCCMS, SCCMS; cholinergic receptor, nicotinic, delta (muscle); K04816 nicotinic acetylcholine receptor delta (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Acetylcholine receptor subunit delta (Precursor) GN=CHRND OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: acetylcholine receptor subunit delta isoform X1 [Galeopterus variegatus]
ENSG00000135905(DOCK10)	--	8.773439382	1370	10.8985798	1677	10.80578734	1648	9.805667155	1522	7.654803922	1194	7.525554521	1154	0.978449255	0.120831602	normal	0.31287568	-0.510957493	normal	0.2471958	-0.521789139	normal	0.150357672	-0.30080247	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Dedicator of cytokinesis;; C2 domain in Dock180 and Zizimin proteins;; Domain of unknown function (DUF3398);; PH domain	Dedicator of cytokinesis protein 10 GN=DOCK10 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 10 [Tupaia chinensis]
ENSG00000135912(TTLL4)	--	9.516933181	869	8.57032824	737	11.06467358	935	6.302934879	554	5.376112307	495	5.815934014	530	0.014848775	-0.678785525	normal	0.106847494	-0.594164491	normal	0.000363971	-0.82546783	normal	1.01E-05	-0.707441912	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16601|0|hsa:9654|TTLL4; tubulin tyrosine ligase-like family, member 4; K16601 tubulin polyglutamylase TTLL4 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin polyglutamylase TTLL4 GN=TTLL4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin polyglutamylase TTLL4 [Galeopterus variegatus]
ENSG00000135913(USP37)	--	5.276939756	717	5.912267753	805	5.397197264	679	2.97490252	410	3.575594331	490	3.489872349	468	0.00047517	-0.834782829	normal	0.005482538	-0.735842535	normal	0.22410412	-0.543727172	normal	2.32E-05	-0.707056424	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11850|0|hsa:57695|USP37; ubiquitin specific peptidase 37 (EC:3.4.19.12); K11850 ubiquitin carboxyl-terminal hydrolase 26/29/37 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin interaction motif	Ubiquitin carboxyl-terminal hydrolase 37 GN=USP37 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 37 [Ceratotherium simum simum]
ENSG00000135914(HTR2B)	--	0.147374	5	0.502686	17	0.23555	7	0.117519	4	0.0856661	2	0.058304	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04157|0|hsa:3357|HTR2B, 5-HT(2B), 5-HT2B; 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled; K04157 5-hydroxytryptamine receptor 2 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Gap junction (ko04540);; Serotonergic synapse (ko04726);; Inflammatory mediator regulation of TRP channels (ko04750)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv	5-hydroxytryptamine receptor 2B GN=HTR2B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 5-hydroxytryptamine receptor 2B [Equus caballus] 
ENSG00000135916(ITM2C)	--	63.88498572	2432	55.9176962	2091	58.000785	2264	36.08309211	1404	40.45461774	1572	40.60196438	1514	0.000131737	-0.822739182	normal	0.659570894	-0.432656168	normal	0.075148105	-0.588316304	normal	1.15E-05	-0.616947399	normal	--	--	--	K18265|1.5682e-161|ptr:459998|ITM2C; integral membrane protein 2C; K18265 integral membrane protein 2C (A)	--	[S]	Function unknown	BRICHOS domain	CT-BRI3 GN=ITM2C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: integral membrane protein 2C isoform X1 [Mustela putorius furo] 
ENSG00000135917(SLC19A3)	--	4.990406	277	3.3881	181	4.378657	223	2.517812003	141	3.770588	192	2.4107767	138	0.000398527	-0.99711615	normal	0.964430276	0.063177513	normal	0.144259932	-0.694620787	normal	0.103480798	-0.552962808	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14610|0|hsa:80704|SLC19A3, BBGD, THMD2, THTR2; solute carrier family 19 (thiamine transporter), member 3; K14610 solute carrier family 19 (thiamine transporter), member 2/3 (A)"	Vitamin digestion and absorption (ko04977)	[H]	Coenzyme transport and metabolism	Reduced folate carrier;; Major Facilitator Superfamily	Thiamine transporter 2 GN=SLC19A3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: thiamine transporter 2-like [Ceratotherium simum simum]
ENSG00000135919(SERPINE2)	--	49.89804013	1831	50.20964504	1801	55.31582345	1989	118.9196416	4356	113.6302379	4168	108.3976393	3973	1.85E-11	1.218856921	up	1.74E-10	1.188455861	up	3.28E-07	0.989351345	normal	1.99E-17	1.131386586	up	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K16643|0|ptr:459980|SERPINE2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; K16643 glia-derived nexin (A)"	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Glia-derived nexin (Precursor) GN=SERPINE2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: glia-derived nexin [Balaenoptera acutorostrata scammoni]
ENSG00000135924(DNAJB2)	--	18.647437	778	22.32229113	969	15.640654	724	19.4325363	779	20.2450825	807	21.65470543	851	0.976288934	-0.028922011	normal	0.913615263	-0.284866604	normal	0.945542116	0.224445133	normal	0.896561008	-0.041280879	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K09508|1.73588e-178|ggo:101142087|DNAJB2; dnaJ homolog subfamily B member 2; K09508 DnaJ homolog subfamily B member 2 (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily B member 2 GN=DNAJB2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 2 isoform X3 [Galeopterus variegatus]
ENSG00000135925(WNT10A)	--	0.028505279	1	0	0	0	0	0	0	0.135148652	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K01357|0|pps:100988140|WNT10A; wingless-type MMTV integration site family, member 10A; K01357 wingless-type MMTV integration site family, member 10 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-10a (Precursor) GN=WNT10A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein Wnt-10a isoform X1 [Mustela putorius furo] 
ENSG00000135926(TMBIM1)	--	79.81270844	2592	78.85807402	2621	84.5947357	2809	68.49671589	2063	53.66337369	1781	59.33511633	2035	0.8616657	-0.35991441	normal	0.109522743	-0.578448801	normal	0.492361003	-0.473018736	normal	0.001372399	-0.469554228	normal	[R]	General function prediction only	--	"K06890|2.94701e-140|hsa:64114|TMBIM1, LFG3, MST100, MSTP100, RECS1; transmembrane BAX inhibitor motif containing 1; K06890 (A)"	--	[T]	Signal transduction mechanisms	Inhibitor of apoptosis-promoting Bax1	Protein lifeguard 3 GN=TMBIM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein lifeguard 3 isoform X2 [Galeopterus variegatus] 
ENSG00000135929(CYP27A1)	--	0.031557772	1	0.0231798	1	0	0	0.031413729	1	0.061380025	1	0.091550484	1	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00488|0|hsa:1593|CYP27A1, CP27, CTX, CYP27; cytochrome P450, family 27, subfamily A, polypeptide 1 (EC:1.14.13.15); K00488 cholestanetriol 26-monooxygenase [EC:1.14.13.15] (A)"	Primary bile acid biosynthesis (ko00120);; PPAR signaling pathway (ko03320)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	"Sterol 26-hydroxylase, mitochondrial (Precursor) GN=CYP27A1 OS=Homo sapiens (Human) PE=1 SV=1"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: sterol 26-hydroxylase, mitochondrial-like isoform X1 [Myotis lucifugus]"
ENSG00000135930(EIF4E2)	--	46.07210691	1487	46.18555643	1581	38.395784	1403	34.45796503	1103	34.21589916	1198	34.20004109	1040	0.498459369	-0.461248418	normal	0.680065184	-0.421171578	normal	0.588754877	-0.439670344	normal	0.003766093	-0.441788989	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation initiation factor activity (GO:0003743);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: translational initiation (GO:0006413);; 	K03259|0|pps:100992392|EIF4E2; eukaryotic translation initiation factor 4E family member 2; K03259 translation initiation factor 4E (A)	RNA transport (ko03013);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Insulin signaling pathway (ko04910)	[J]	"Translation, ribosomal structure and biogenesis"	Eukaryotic initiation factor 4E	Eukaryotic translation initiation factor 4E type 2 GN=EIF4E2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4E type 2 isoform 1 [Orcinus orca] 
ENSG00000135931(ARMC9)	--	5.841855737	462	7.254578402	554	7.587546238	511	3.993973613	335	6.23488387	386	4.253953503	319	0.464600185	-0.492630769	normal	0.277819057	-0.540932348	normal	0.028704384	-0.685466574	normal	0.003028947	-0.575384812	normal	--	--	--	--	--	--	--	--	LisH domain-containing protein ARMC9 GN=ARMC9 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: lisH domain-containing protein ARMC9 isoform X3 [Equus caballus]
ENSG00000135932(CAB39)	--	23.26765818	1418	23.21335013	1370	22.61550863	1358	21.25626291	1315	22.64527162	1371	16.97576346	1051	0.975601859	-0.139470014	normal	0.982555518	-0.020351423	normal	0.786829871	-0.377532988	normal	0.383245793	-0.171636021	normal	--	--	--	K08272|0|tup:102491762|CAB39; calcium binding protein 39; K08272 calcium binding protein 39 (A)	mTOR signaling pathway (ko04150);; AMPK signaling pathway (ko04152)	[S]	Function unknown	Mo25-like	Calcium-binding protein 39 GN=CAB39 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: calcium-binding protein 39 isoform X1 [Bos taurus]
ENSG00000135940(COX5B)	--	144.505	1286	140.435	1284	141.983	1314	108.362	1014	108.116	955	114.21	1036	0.793908985	-0.373161788	normal	0.571441123	-0.447885009	normal	0.840656027	-0.350776934	normal	0.013962546	-0.391290039	normal	--	--	Molecular Function: cytochrome-c oxidase activity (GO:0004129);; Cellular Component: mitochondrial envelope (GO:0005740);; 	"K02265|1.30504e-78|hsa:1329|COX5B, COXVB; cytochrome c oxidase subunit Vb (EC:1.9.3.1); K02265 cytochrome c oxidase subunit 5b (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome c oxidase subunit Vb	"Cytochrome c oxidase subunit 5B, mitochondrial (Precursor) GN=COX5B OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: cytochrome c oxidase subunit 5B, mitochondrial-like [Physeter catodon]"
ENSG00000135945(REV1)	--	7.05593	586	7.1832591	658	5.92492	539	4.523309	383	4.776195	393	4.198488	351	0.050829105	-0.642288317	normal	0.004135962	-0.762690226	normal	0.079018672	-0.624915925	normal	0.000144023	-0.683504927	normal	[L]	"Replication, recombination and repair"	Molecular Function: damaged DNA binding (GO:0003684);; Biological Process: DNA repair (GO:0006281);; 	"K03515|0|hsa:51455|REV1, REV1L; REV1, polymerase (DNA directed); K03515 DNA repair protein REV1 [EC:2.7.7.-] (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	impB/mucB/samB family;; impB/mucB/samB family C-terminal domain;; Domain of unknown function (DUF4414);; BRCA1 C Terminus (BRCT) domain;; IMS family HHH motif;; twin BRCT domain	DNA repair protein REV1 GN=REV1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein REV1 isoform X1 [Canis lupus familiaris]
ENSG00000135951(TSGA10)	--	0.257535632	19	0.2382788	14	0.703426054	43	0.15884421	12	0.209711502	15	0.293404823	21	--	--	--	--	--	--	0.711512783	-0.991363071	normal	--	--	--	--	--	--	--	--	--	--	--	Testis-specific gene 10 protein GN=TSGA10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: testis-specific gene 10 protein isoform X1 [Ochotona princeps] 
ENSG00000135953(MFSD9)	--	5.35691293	423	5.844878927	469	6.035667621	490	3.99477574	317	4.516010694	356	4.423711751	352	0.637627518	-0.445132038	normal	0.707824293	-0.417586378	normal	0.488297631	-0.483728072	normal	0.031603964	-0.45182401	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Major Facilitator Superfamily;; Sugar (and other) transporter;; MFS/sugar transport protein	Major facilitator superfamily domain-containing protein 9 GN=MFSD9 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: major facilitator superfamily domain-containing protein 9 [Equus caballus]
ENSG00000135956(TMEM127)	--	25.90247	1925	29.39888	2184	28.940718	2089	22.950692	1699	22.15713	1702	25.74035	1949	0.966917975	-0.21082559	normal	0.816058108	-0.380868769	normal	0.983611746	-0.108288665	normal	0.180085465	-0.233050617	normal	--	--	--	--	--	--	--	--	Transmembrane protein 127 GN=TMEM127 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 127 [Camelus ferus]
ENSG00000135960(EDAR)	--	0.034943291	3	0.05769505	5	0	0	0.034923443	3	0.045324868	3	0.02299821	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05162|0|mcf:102120238|EDAR; ectodysplasin A receptor; K05162 tumor necrosis factor receptor superfamily member EDAR (A)	Cytokine-cytokine receptor interaction (ko04060)	--	--	Death domain	Tumor necrosis factor receptor superfamily member EDAR (Precursor) GN=EDAR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member EDAR isoform X1 [Canis lupus familiaris]
ENSG00000135966(TGFBRAP1)	--	10.9442964	1145	12.613393	1285	13.953064	1300	7.774410901	798	9.241489526	929	9.393218949	947	0.159665208	-0.550828474	normal	0.401242078	-0.488764682	normal	0.482288958	-0.464730579	normal	0.001031246	-0.500719793	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar sorting protein 39 domain 2;; Vacuolar sorting protein 39 domain 1;; Region in Clathrin and VPS;; CNH domain	Transforming growth factor-beta receptor-associated protein 1 GN=TGFBRAP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transforming growth factor-beta receptor-associated protein 1 [Ceratotherium simum simum]
ENSG00000135968(GCC2)	--	10.67447003	1243	11.681984	1264	12.15371301	1390	11.39792795	1364	10.94056543	1313	10.0215791	1362	0.978700444	0.10306345	normal	0.981634277	0.033404682	normal	0.982717939	-0.037608285	normal	0.913836245	0.030611295	normal	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	GRIP domain	GRIP and coiled-coil domain-containing protein 2 GN=GCC2 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: GRIP and coiled-coil domain-containing protein 2 [Oryctolagus cuniculus]
ENSG00000135972(MRPS9)	--	20.13200209	545	22.76293764	619	22.4012	592	14.651817	402	14.63344	391	10.88993342	296	0.521883997	-0.468348927	normal	0.025387095	-0.68208113	normal	9.55E-06	-1.004588447	down	8.03E-05	-0.711304324	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02996|0|hsa:64965|MRPS9, MRP-S9, RPMS9, S9mt; mitochondrial ribosomal protein S9; K02996 small subunit ribosomal protein S9 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S9/S16	"28S ribosomal protein S9, mitochondrial (Precursor) GN=MRPS9 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S9, mitochondrial [Galeopterus variegatus]"
ENSG00000135973(GPR45)	--	0.305981	5	0.36213	6	0.353241	5	0.18367	3	0.295081	4	0.120979	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08409|0|hsa:11250|GPR45, PSP24, PSP24(ALPHA), PSP24A; G protein-coupled receptor 45; K08409 G protein-coupled receptor 45 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srx;; Serpentine type 7TM GPCR chemoreceptor Srsx	Probable G-protein coupled receptor 45 GN=GPR45 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 45 [Oryctolagus cuniculus]
ENSG00000135974(C2orf49)	--	10.37764173	516	8.995426189	499	13.30247139	569	6.729917041	359	6.951846834	378	6.906328216	352	0.238788666	-0.552236119	normal	0.694340522	-0.420610387	normal	0.018278618	-0.698760314	normal	0.003422514	-0.561565801	normal	--	--	Biological Process: embryonic morphogenesis (GO:0048598);; Cellular Component: tRNA-splicing ligase complex (GO:0072669);; 	"K15432|4.08148e-121|pon:100451291|C2AH2orf49; chromosome 2A open reading frame, human C2orf49; K15432 ashwin (A)"	--	--	--	Developmental protein	Ashwin GN=C2orf49 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ashwin isoform X1 [Felis catus]
ENSG00000135976(ANKRD36)	--	2.469904578	347	2.71605643	382	2.291569256	327	1.707788815	224	1.788672071	207	1.726646043	252	0.090525774	-0.65860815	normal	0.000873451	-0.900447005	normal	0.810411437	-0.382139284	normal	0.003206412	-0.64974044	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 36A GN=ANKRD36 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like [Physeter catodon]
ENSG00000135999(EPC2)	--	5.892093018	427	7.567322128	505	5.798946977	401	4.617322022	319	4.724116599	353	5.733772959	410	0.622747692	-0.449632563	normal	0.310552978	-0.536110504	normal	0.969663618	0.023642053	normal	0.161446319	-0.321704585	normal	--	--	--	"K11322|0|hsa:26122|EPC2, EPC-LIKE; enhancer of polycomb homolog 2 (Drosophila); K11322 enhancer of polycomb-like protein (A)"	--	[K]	Transcription	Enhancer of Polycomb C-terminus;; Enhancer of polycomb-like	Enhancer of polycomb homolog 2 GN=EPC2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: enhancer of polycomb homolog 2 isoform X1 [Felis catus] 
ENSG00000136002(ARHGEF4)	--	2.1960284	282	1.312147889	166	1.762978836	242	1.44130274	200	1.485188745	210	1.938965906	245	0.499980484	-0.523124566	normal	0.905503642	0.315221305	normal	0.967105221	0.009424725	normal	0.851871876	-0.095438945	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K05769|0|mcf:102136064|uncharacterized LOC102136064; K05769 Rho guanine nucleotide exchange factor 4 (A)	Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	RhoGEF domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; PH domain	Rho guanine nucleotide exchange factor 4 GN=ARHGEF4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 4 isoform X1 [Oryctolagus cuniculus]
ENSG00000136003(ISCU)	--	48.89938859	811	54.81525276	922	55.09707469	922	56.15416472	937	56.53649025	936	66.01053215	1098	0.961891304	0.17720236	normal	0.978212231	0.000314709	normal	0.942135205	0.243381714	normal	0.522872308	0.141593794	normal	[C]	Energy production and conversion	Molecular Function: iron ion binding (GO:0005506);; Biological Process: iron-sulfur cluster assembly (GO:0016226);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	--	--	[C]	Energy production and conversion	NifU-like N terminal domain	"Iron-sulfur cluster assembly enzyme ISCU, mitochondrial (Precursor) GN=ISCU OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: iron-sulfur cluster assembly enzyme ISCU, mitochondrial [Loxodonta africana] "
ENSG00000136010(ALDH1L2)	--	3.324951327	448	3.455142426	442	3.130276	395	2.312308	294	2.067544578	276	4.680646922	608	0.083594198	-0.635801404	normal	0.033213415	-0.697754067	normal	0.086150686	0.612024385	normal	0.861169441	-0.144599473	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Biological Process: biosynthetic process (GO:0009058);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: hydroxymethyl-, formyl- and related transferase activity (GO:0016742);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00289|0|hsa:160428|ALDH1L2, mtFDH; aldehyde dehydrogenase 1 family, member L2 (EC:1.5.1.6); K00289 formyltetrahydrofolate dehydrogenase [EC:1.5.1.6] (A)"	One carbon pool by folate (ko00670)	[F]	Nucleotide transport and metabolism	"Aldehyde dehydrogenase family;; Formyl transferase;; Formyl transferase, C-terminal domain;; Phosphopantetheine attachment site"	Mitochondrial 10-formyltetrahydrofolate dehydrogenase GN=ALDH1L2 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: mitochondrial 10-formyltetrahydrofolate dehydrogenase-like [Myotis lucifugus]
ENSG00000136011(STAB2)	--	0.015634346	3	0.016137331	3	0.030813513	5	0.215010301	3	0.231244911	1	0.0103844	2	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	--	--	[T]	Signal transduction mechanisms	Fasciclin domain;; EGF domain;; Extracellular link domain	190 kDa form stabilin-2 (Precursor) OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: stabilin-2 [Ceratotherium simum simum]
ENSG00000136014(USP44)	--	1.183133482	65	0.453307614	22	0.876451928	37	0.369356793	22	0.636381602	29	0.211029605	12	0.005473192	-1.528717227	down	0.979677017	0.355768941	normal	0.201412091	-1.51871154	normal	0.312683427	-0.999335124	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11834|0|hsa:84101|USP44; ubiquitin specific peptidase 44 (EC:3.4.19.12); K11834 ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 44 GN=USP44 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 44 [Orcinus orca]
ENSG00000136021(SCYL2)	--	14.540143	1242	15.48328114	1284	16.32606655	1357	17.77287883	1538	17.06806693	1442	16.53177587	1423	0.93074067	0.277249391	normal	0.974403109	0.145837256	normal	0.982097296	0.060158026	normal	0.420956451	0.160001236	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17541|0|hsa:55681|SCYL2, CVAK104; SCY1-like 2 (S. cerevisiae); K17541 SCY1-like protein 2 (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	SCY1-like protein 2 GN=SCYL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SCY1-like protein 2 isoform X3 [Equus przewalskii]
ENSG00000136026(CKAP4)	--	74.285147	4354	65.83266192	3958	67.68978111	4078	79.3183	4691	83.88374227	4918	64.2005	3789	0.991969022	0.076695753	normal	0.959879288	0.291773386	normal	0.989605143	-0.114292095	normal	0.693589362	0.091101556	normal	--	--	--	"K13999|0|hsa:10970|CKAP4, CLIMP-63, ERGIC-63, p63; cytoskeleton-associated protein 4; K13999 cytoskeleton-associated protein 4 (A)"	Protein processing in endoplasmic reticulum (ko04141)	--	--	--	Cytoskeleton-associated protein 4 GN=CKAP4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: cytoskeleton-associated protein 4, partial [Tupaia chinensis]"
ENSG00000136040(PLXNC1)	--	0.1853	12	0.170476101	12	0.27786	17	0.2305597	16	0.402801	26	0.2199146	16	--	--	--	0.909251941	1.006165722	normal	--	--	--	--	--	--	--	--	--	"K06572|0|hsa:10154|PLXNC1, CD232, PLXN-C1, VESPR; plexin C1; K06572 plexin C (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; Plexin repeat;; IPT/TIG domain	Plexin-C1 (Precursor) GN=PLXNC1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: plexin-C1 [Odobenus rosmarus divergens]
ENSG00000136044(APPL2)	--	12.29619678	676	11.43599967	636	13.01417826	707	20.7524999	1160	22.23096503	1319	21.77033053	1241	0.002192941	0.746887021	normal	5.31E-07	1.029183793	up	0.000454848	0.802117792	normal	2.79E-09	0.860872377	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; PH domain;; Phosphotyrosine-binding domain	DCC-interacting protein 13-beta GN=APPL2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: DCC-interacting protein 13-beta isoform 1 [Ceratotherium simum simum]
ENSG00000136045(PWP1)	--	34.470843	1472	36.191056	1539	33.125367	1386	41.23187	1704	41.22928	1762	32.862797	1424	0.97146587	0.180140534	normal	0.973121712	0.173634584	normal	0.983094431	0.030697402	normal	0.527981335	0.131510372	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14791|0|pps:100967662|PWP1; PWP1 homolog (S. cerevisiae); K14791 periodic tryptophan protein 1 (A)	--	[S]	Function unknown	"WD domain, G-beta repeat"	Periodic tryptophan protein 1 homolog GN=PWP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: periodic tryptophan protein 1 homolog [Ailuropoda melanoleuca] 
ENSG00000136048(DRAM1)	--	22.51201497	1263	22.1909038	1260	22.00671986	1257	32.22655386	1845	32.44946145	1822	45.99855569	2626	0.273036041	0.515412402	normal	0.319621972	0.510160831	normal	3.70E-08	1.053694134	up	0.014188003	0.715210394	normal	--	--	--	--	--	[S]	Function unknown	Frag1/DRAM/Sfk1 family	DNA damage-regulated autophagy modulator protein 1 GN=DRAM1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DNA damage-regulated autophagy modulator protein 1 [Orycteropus afer afer]
ENSG00000136051(WASHC4)	--	16.11695378	1479	17.44387939	1570	19.16411288	1658	19.5220151	1785	17.903107	1593	21.52371552	1805	0.954872401	0.240242327	normal	0.984213676	-0.000444425	normal	0.981381245	0.114163562	normal	0.581785096	0.117912257	normal	--	--	--	"K18465|0|hsa:23325|MRT43, SWIP; KIAA1033; K18465 WASH complex subunit 7 (A)"	--	[S]	Function unknown	"WASH complex subunit 7, N-terminal;; WASH complex subunit 7;; WASH complex subunit 7, C-terminal"	WASH complex subunit 7 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	"WASH complex subunit 7, partial [Bos mutus]"
ENSG00000136052(SLC41A2)	--	11.04358522	452	8.543542113	498	8.641982929	379	17.39949426	916	16.34816763	828	19.64247853	907	3.76E-06	0.985792697	normal	0.009762793	0.710368589	normal	4.90E-10	1.247294918	up	4.47E-10	0.974523293	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; 	"K15122|0|hsa:84102|SLC41A2, SLC41A1-L1; solute carrier family 41 (magnesium transporter), member 2; K15122 solute carrier family 41 (A)"	--	[P]	Inorganic ion transport and metabolism	Divalent cation transporter	Solute carrier family 41 member 2 GN=SLC41A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 41 member 2 [Galeopterus variegatus]
ENSG00000136059(VILL)	--	0.189457263	7	0.262552544	10	0.116268369	5	0	0	0.078916179	2	0.053489824	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	--	--	[Z]	Cytoskeleton	Gelsolin repeat;; Villin headpiece domain	Villin-like protein GN=VILL OS=Homo sapiens (Human) PE=2 SV=3	Z	Cytoskeleton	PREDICTED: villin-like protein isoform X1 [Galeopterus variegatus]
ENSG00000136068(FLNB)	--	114.0983803	21066	106.215656	18882	106.3105	20516	154.4294301	27889	120.91041	22523	119.44376	22047	0.965982033	0.373923772	normal	0.993445665	0.23294376	normal	0.997570328	0.095534644	normal	0.261023389	0.239185122	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K04437|0|hsa:2317|FLNB, ABP-278, ABP-280, AOI, FH1, FLN-B, FLN1L, LRS1, SCT, TABP, TAP; filamin B, beta; K04437 filamin (A)"	MAPK signaling pathway (ko04010);; Focal adhesion (ko04510);; Salmonella infection (ko05132);; Proteoglycans in cancer (ko05205)	[Z]	Cytoskeleton	Filamin/ABP280 repeat;; Calponin homology (CH) domain;; Bacterial Ig-like domain (group 1);; Y_Y_Y domain;; Bacterial Ig-like domain (group 3);; YtkA-like;; Uncharacterized protein conserved in bacteria (DUF2141)	Filamin-B GN=FLNB OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: filamin-B isoform X4 [Panthera tigris altaica]
ENSG00000136098(NEK3)	--	3.476776797	148	3.203113584	140	2.923625742	130	2.827944612	119	3.28346848	142	1.775866849	78	0.912584691	-0.341505011	normal	0.966897446	-0.000952242	normal	0.324153675	-0.734112783	normal	0.429619118	-0.324487336	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08857|0|ptr:452737|NEK3; NIMA-related kinase 3; K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase Nek3 GN=NEK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Nek3 [Galeopterus variegatus]
ENSG00000136100(VPS36)	--	8.7899027	620	8.488336	600	8.192706002	571	9.338996	664	9.197132	646	8.973794	634	0.972378623	0.06792011	normal	0.9702358	0.084938759	normal	0.963642935	0.142342736	normal	0.722855124	0.096824668	normal	--	--	Molecular Function: phosphatidylinositol-3-phosphate binding (GO:0032266);; Molecular Function: ubiquitin binding (GO:0043130);; 	K12190|0|ggo:101131299|VPS36; vacuolar protein-sorting-associated protein 36 isoform 1; K12190 ESCRT-II complex subunit VPS36 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	EAP30/Vps36 family;; Vacuolar protein sorting protein 36 Vps36	Vacuolar protein-sorting-associated protein 36 GN=VPS36 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein-sorting-associated protein 36 isoform X8 [Canis lupus familiaris]
ENSG00000136104(RNASEH2B)	--	14.06101001	376	20.29206672	420	15.72862752	393	13.029528	350	12.06793382	343	13.342177	355	0.960123819	-0.133643793	normal	0.883066566	-0.312360341	normal	0.956977449	-0.154376398	normal	0.457997625	-0.203310246	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K10744|0|pon:100443564|RNASEH2B; ribonuclease H2, subunit B; K10744 ribonuclease H2 subunit B (A)"	DNA replication (ko03030)	[S]	Function unknown	Ydr279p protein family (RNase H2 complex component)	Ribonuclease H2 subunit B GN=RNASEH2B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: ribonuclease H2 subunit B [Eptesicus fuscus]
ENSG00000136108(CKAP2)	--	21.60830288	1346	23.04225697	1390	22.34081504	1328	26.25900078	1619	23.459575	1425	23.337661	1434	0.954507763	0.235347098	normal	0.982910163	0.014434968	normal	0.979547469	0.10238621	normal	0.581825633	0.118297297	normal	--	--	--	"K16769|0|hsa:26586|CKAP2, LB1, TMAP, se20-10; cytoskeleton associated protein 2; K16769 cytoskeleton-associated protein 2 (A)"	--	--	--	Cytoskeleton-associated protein 2 C-terminus	Cytoskeleton-associated protein 2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: cytoskeleton-associated protein 2 isoform 1 [Orcinus orca]
ENSG00000136110(CNMD)	--	0.0399665	1	0.039584793	1	0	0	0	0	0.03886	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	BRICHOS domain	Chondromodulin-1 (Precursor) GN=LECT1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	Leukocyte cell-derived chemotaxin 1 [Tupaia chinensis]
ENSG00000136111(TBC1D4)	--	8.624216024	1011	8.646664693	1015	8.494321409	986	8.03433454	939	7.53131281	883	6.0909626	703	0.970978244	-0.137201768	normal	0.949941935	-0.222065867	normal	0.359379366	-0.495450024	normal	0.129489969	-0.276492242	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17902|0|pps:100987740|TBC1D4; TBC1 domain family, member 4; K17902 TBC1 domain family member 4 (A)"	Thyroid hormone signaling pathway (ko04919)	[R]	General function prediction only	Rab-GTPase-TBC domain;; Domain of unknown function (DUF3350);; Phosphotyrosine interaction domain (PTB/PID)	TBC1 domain family member 4 GN=TBC1D4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: TBC1 domain family member 4 isoform 3 [Ceratotherium simum simum]
ENSG00000136114(THSD1)	--	3.822569572	251	2.876928393	160	3.27183736	207	6.478055	396	4.699676969	281	4.8813064	316	0.126402714	0.62391656	normal	0.023537848	0.785400782	normal	0.238913947	0.59843839	normal	0.021923727	0.662256544	normal	--	--	--	--	--	--	--	Thrombospondin type 1 domain	Thrombospondin type-1 domain-containing protein 1 (Precursor) GN=THSD1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: thrombospondin type-1 domain-containing protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000136122(BORA)	--	4.10125	134	4.897909001	139	3.387796	105	5.04986	173	5.97653	169	4.5127821	152	0.907675563	0.3343256	normal	0.937199278	0.257963166	normal	0.732675381	0.519142521	normal	0.320903061	0.364114505	normal	--	--	--	"K16831|0|hsa:79866|BORA, C13orf34; bora, aurora kinase A activator; K16831 protein aurora borealis (A)"	--	--	--	Protein aurora borealis N-terminus	Protein aurora borealis GN=BORA OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: protein aurora borealis isoform X1 [Galeopterus variegatus]
ENSG00000136141(LRCH1)	--	4.811138565	445	4.27689066	391	5.528469421	505	4.848054988	447	5.468406235	502	4.427059331	409	0.970376806	-0.02427913	normal	0.852450463	0.33793606	normal	0.881238242	-0.311435653	normal	0.999369473	-0.00281176	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Calponin homology (CH) domain;; Leucine rich repeat;; CAMSAP CH domain;; Leucine Rich repeat	Leucine-rich repeat and calponin homology domain-containing protein 1 GN=LRCH1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: leucine-rich repeat and calponin homology domain-containing protein 1 isoform X4 [Galeopterus variegatus]
ENSG00000136143(SUCLA2)	--	16.36847646	585	19.03046871	654	20.38898172	724	18.44388272	654	21.6752517	730	21.97552991	766	0.96579235	0.129699478	normal	0.965674352	0.136879579	normal	0.973949569	0.072915167	normal	0.667917074	0.110846939	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01900|0|hsa:8803|SUCLA2, A-BETA, MTDPS5, SCS-betaA; succinate-CoA ligase, ADP-forming, beta subunit (EC:6.2.1.5); K01900 succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] (A)"	Citrate cycle (TCA cycle) (ko00020);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	ATP-grasp domain;; CoA-ligase;; ATP-grasp domain	"Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial (Precursor) GN=SUCLA2 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial [Vicugna pacos]"
ENSG00000136144(RCBTB1)	--	11.173145	718	11.43086807	744	11.8352953	756	9.80104016	637	9.439384457	606	13.05457204	843	0.950652402	-0.20306104	normal	0.877634317	-0.316696699	normal	0.966413705	0.148573382	normal	0.705062122	-0.10884255	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: protein binding (GO:0005515);; 	K11494|0|ptr:452720|RCBTB1; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1; K11494 RCC1 and BTB domain-containing protein (A)	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat;; BTB/POZ domain;; BTB And C-terminal Kelch	RCC1 and BTB domain-containing protein 1 GN=RCBTB1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: RCC1 and BTB domain-containing protein 1 [Condylura cristata]
ENSG00000136146(MED4)	--	16.22232161	429	16.638759	443	17.3795001	483	18.5580744	496	17.96476115	470	17.18736124	438	0.953260734	0.177937182	normal	0.968282653	0.063716318	normal	0.959565677	-0.148893991	normal	0.940244611	0.029869711	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15146|1.79753e-158|pps:100972791|MED4; mediator complex subunit 4; K15146 mediator of RNA polymerase II transcription subunit 4 (A)	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	Vitamin-D-receptor interacting Mediator subunit 4	Mediator of RNA polymerase II transcription subunit 4 GN=MED4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 4 [Ceratotherium simum simum]
ENSG00000136147(PHF11)	--	4.272042545	98	5.063266647	115	4.209171385	92	5.422815072	129	5.159610408	117	7.215545501	161	0.914974778	0.360742922	normal	0.968235015	0.003403736	normal	0.116712887	0.789135127	normal	0.322417235	0.395362539	normal	--	--	--	--	--	[K]	Transcription	PHD-like zinc-binding domain;; PHD-zinc-finger like domain	PHD finger protein 11 GN=PHF11 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: PHD finger protein 11 isoform X2 [Ursus maritimus]
ENSG00000136152(COG3)	--	5.833529	393	5.4253792	399	5.210459	390	5.703736	412	6.174267467	444	6.47927501	479	0.969128073	0.037140946	normal	0.960627716	0.132268977	normal	0.902970632	0.287253355	normal	0.581237946	0.154852984	normal	--	--	Cellular Component: cis-Golgi network (GO:0005801);; Biological Process: intracellular protein transport (GO:0006886);; Cellular Component: membrane (GO:0016020);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec34-like family	Conserved oligomeric Golgi complex subunit 3 GN=COG3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: conserved oligomeric Golgi complex subunit 3 [Galeopterus variegatus]
ENSG00000136153(LMO7)	--	12.02636755	1094	14.20205791	1347	14.79994466	1232	13.56136783	1283	11.49624822	1061	14.017303	1275	0.961868809	0.198818133	normal	0.820382797	-0.365288437	normal	0.981590166	0.04115389	normal	0.879428893	-0.042689127	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06084|0|ggo:101137534|LMO7; LIM domain only protein 7 isoform 1; K06084 F-box protein 20 (A)	Adherens junction (ko04520)	--	--	Calponin homology (CH) domain;; PDZ domain (Also known as DHR or GLGF);; LIM domain	LIM domain only protein 7 GN=LMO7 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: LIM domain only protein 7 isoform X8 [Equus caballus]
ENSG00000136155(SCEL)	--	0.187005406	12	0.249560046	16	0.031843266	1	0.135530861	9	0.189695403	12	0.251878906	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	--	Sciellin GN=SCEL OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: sciellin [Camelus ferus]
ENSG00000136156(ITM2B)	--	57.179766	2905	72.320249	3188	68.383584	2933	86.4157571	3532	80.140057	3516	130.3974907	5149	0.967086808	0.250994376	normal	0.987713637	0.119802754	normal	0.00023871	0.803307097	normal	0.207816757	0.414209724	normal	--	--	--	"K18264|3.01312e-159|ptr:452714|ITM2B, Bri, imBRI2; integral membrane protein 2B; K18264 integral membrane protein 2B (A)"	--	[S]	Function unknown	BRICHOS domain	Bri23 peptide GN=ITM2B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: integral membrane protein 2B [Equus caballus] 
ENSG00000136158(SPRY2)	--	4.221034	166	5.054968	198	4.32673	170	5.549573	220	6.413742	254	4.664968	182	0.861125264	0.372485048	normal	0.881772296	0.335633121	normal	0.964390274	0.089344003	normal	0.415048244	0.275102715	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	K17383|0|ptr:452616|SPRY2; sprouty homolog 2 (Drosophila); K17383 protein sprouty homolog 2 (A)	Jak-STAT signaling pathway (ko04630);; MicroRNAs in cancer (ko05206)	--	--	Sprouty protein (Spry)	Protein sprouty homolog 2 GN=SPRY2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein sprouty homolog 2 [Galeopterus variegatus] 
ENSG00000136159(NUDT15)	--	14.44393337	464	13.03979966	422	13.63246	437	16.03152698	522	14.55463491	465	16.23598394	521	0.961811469	0.138659701	normal	0.963036369	0.118157678	normal	0.929831959	0.244582549	normal	0.522598383	0.167572417	normal	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	K03574|3.13737e-105|ptr:741013|NUDT15; nudix (nucleoside diphosphate linked moiety X)-type motif 15; K03574 8-oxo-dGTP diphosphatase [EC:3.6.1.55] (A)	--	--	--	NUDIX domain	Probable 8-oxo-dGTP diphosphatase NUDT15 GN=NUDT15 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: probable 8-oxo-dGTP diphosphatase NUDT15 [Ceratotherium simum simum]
ENSG00000136160(EDNRB)	--	0.044985688	2	0.016081722	1	0.032119541	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04198|0|pps:100986370|EDNRB; endothelin receptor type B; K04198 endothelin receptor type B (A)	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Neuroactive ligand-receptor interaction (ko04080);; Melanogenesis (ko04916);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Endothelin B receptor (Precursor) GN=EDNRB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: endothelin B receptor [Galeopterus variegatus]
ENSG00000136161(RCBTB2)	--	0.484326081	25	0.774838856	39	0.640152415	31	0.519027576	27	0.626788202	33	0.766122825	39	0.986462782	0.075720733	normal	0.977005659	-0.251806665	normal	0.976101068	0.309430627	normal	0.985026733	0.039277818	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: protein binding (GO:0005515);; 	K11494|0|mcf:102146617|RCBTB2; regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2; K11494 RCC1 and BTB domain-containing protein (A)	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat;; BTB/POZ domain;; BTB And C-terminal Kelch	RCC1 and BTB domain-containing protein 2 GN=RCBTB2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: RCC1 and BTB domain-containing protein 2 isoform X2 [Lipotes vexillifer]
ENSG00000136167(LCP1)	--	0.149495948	8	0.181034222	13	0	0	0.588490689	21	0.122703125	8	0.181147274	13	0.910248624	1.213437628	normal	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	"K17276|0|hsa:3936|LCP1, CP64, HEL-S-37, L-PLASTIN, LC64P, LPL, PLS2; lymphocyte cytosolic protein 1 (L-plastin); K17276 plastin-2 (A)"	--	[Z]	Cytoskeleton	Calponin homology (CH) domain;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF hand;; CAMSAP CH domain	Plastin-2 GN=LCP1 OS=Homo sapiens (Human) PE=1 SV=6	Z	Cytoskeleton	PREDICTED: plastin-2 isoform X2 [Panthera tigris altaica]
ENSG00000136169(SETDB2)	--	1.132200075	94	1.730752058	112	1.185028648	108	1.299781511	100	1.161422679	82	1.63264533	137	0.970629172	0.057523459	normal	0.863724545	-0.463877913	normal	0.922753225	0.33073228	normal	1	0.002548785	normal	[R]	General function prediction only	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; 	"K18494|0|ptr:452719|SETDB2; SET domain, bifurcated 2; K18494 histone-lysine N-methyltransferase SETDB2 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[B]	Chromatin structure and dynamics	SET domain;; Pre-SET motif;; Methyl-CpG binding domain	Histone-lysine N-methyltransferase SETDB2 GN=SETDB2 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase SETDB2 isoform X1 [Galeopterus variegatus]
ENSG00000136193(SCRN1)	--	43.83048535	4328	44.06557576	4368	45.5787241	4484	47.16109424	4665	45.37485381	4409	44.44922781	4365	0.991916563	0.077317878	normal	0.992462503	-0.007945199	normal	0.992404553	-0.047079972	normal	0.985612711	0.006727921	normal	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: dipeptidase activity (GO:0016805);; 	"K14358|0|hsa:9805|SCRN1, SES1; secernin 1; K14358 secernin (A)"	--	--	--	Peptidase family C69	Secernin-1 GN=SCRN1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: secernin-1 [Odobenus rosmarus divergens]
ENSG00000136197(C7orf25)	--	9.602221123	307	8.890819877	274	9.44105926	299	7.7510068	244	8.297071706	243	8.463501874	265	0.844323939	-0.360162724	normal	0.946967688	-0.193511188	normal	0.950733178	-0.181468987	normal	0.399073769	-0.247646829	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1308)	UPF0415 protein C7orf25 GN=C7orf25 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"hypothetical protein M91_15832, partial [Bos mutus]"
ENSG00000136205(TNS3)	--	80.03925015	12365	88.60528115	13323	88.1995371	13330	100.8781323	15136	105.1893526	15645	116.0074923	17508	0.987888318	0.260860155	normal	0.992853995	0.210334073	normal	0.941462145	0.385007841	normal	0.137157771	0.286850877	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K18080|0|hsa:64759|TNS3, TEM6, TENS1; tensin 3; K18080 tensin (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	Phosphotyrosine-binding domain;; C2 domain of PTEN tumour-suppressor protein;; SH2 domain	Tensin-3 GN=TNS3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: tensin-3-like [Tupaia chinensis]
ENSG00000136206(SPDYE1)	--	0.298752	13	0.31293	14	0.689983	30	0.135892	6	0.156673	6	0.342382	15	--	--	--	--	--	--	0.899385183	-0.94008728	normal	--	--	--	--	--	--	--	--	--	--	Cell cycle regulatory protein	Speedy protein E1 GN=SPDYE1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: speedy protein E4-like [Ursus maritimus]
ENSG00000136213(CHST12)	--	10.4466353	575	9.3955296	562	10.698814	549	10.49444641	633	9.226296416	547	7.879058009	449	0.968292589	0.107537359	normal	0.970548561	-0.0602914	normal	0.894089822	-0.297474446	normal	0.817737445	-0.071889999	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04742|0|hsa:55501|CHST12, C4S-2, C4ST-2, C4ST2; carbohydrate (chondroitin 4) sulfotransferase 12 (EC:2.8.2.5); K04742 chondroitin 4-sulfotransferase 12 [EC:2.8.2.5] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Sulfotransferase family	Carbohydrate sulfotransferase 12 GN=CHST12 OS=Homo sapiens (Human) PE=1 SV=2	MW	Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: carbohydrate sulfotransferase 12 isoform X1 [Tupaia chinensis] 
ENSG00000136231(IGF2BP3)	--	16.46647155	1210	16.3730266	1191	16.63757976	1150	23.202981	1701	22.67086	1662	16.83348878	1237	0.510296729	0.460049064	normal	0.537738869	0.458825157	normal	0.978149125	0.096797441	normal	0.088810939	0.351288709	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	K13197|0|ptr:744246|IGF2BP3; insulin-like growth factor 2 mRNA binding protein 3; K13197 insulin-like growth factor 2 mRNA-binding protein 3 (A)	--	[AR]	RNA processing and modification;; General function prediction only	"KH domain;; KH domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; KH domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; KH domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; NusA-like KH domain"	Insulin-like growth factor 2 mRNA-binding protein 3 GN=IGF2BP3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: insulin-like growth factor 2 mRNA-binding protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000136235(GPNMB)	--	0.658535	33	1.0665884	55	0.47971147	24	2.164585588	110	2.919096	150	5.7701	305	1.11E-05	1.661388754	up	2.52E-05	1.401765348	up	0	3.578655465	up	0.029917469	2.315494164	normal	--	--	--	--	--	--	--	PKD domain	Transmembrane glycoprotein NMB (Precursor) GN=GPNMB OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane glycoprotein NMB [Galeopterus variegatus]
ENSG00000136237(RAPGEF5)	--	0.488161473	58	0.257747544	30	0.325369203	36	0.09260885	11	0.133573982	16	0.054435724	7	2.25E-05	-2.276187884	down	0.91657371	-0.867534341	normal	0.008694241	-2.147132278	down	0.002919645	-1.888893444	down	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K08019|0|hsa:9771|RAPGEF5, GFR, MR-GEF, REPAC; Rap guanine nucleotide exchange factor (GEF) 5; K08019 Rap guanine nucleotide exchange factor 5 (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif	Rap guanine nucleotide exchange factor 5 GN=RAPGEF5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rap guanine nucleotide exchange factor 5 isoform X2 [Equus przewalskii]
ENSG00000136238(RAC1)	--	216.2029683	7012	221.6275249	7149	212.5171364	6850	254.1472106	8371	222.4085766	7289	222.9081788	7363	0.986630801	0.224696613	normal	0.994920349	0.006551518	normal	0.993969812	0.095877851	normal	0.635877617	0.110244551	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K04392|6.47501e-141|cjc:100404109|RAC1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); K04392 Ras-related C3 botulinum toxin substrate 1 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Sphingolipid signaling pathway (ko04071);; Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Toll-like receptor signaling pathway (ko04620);; Natural killer cell mediated cytotoxicity (ko04650);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Regulation of actin cytoskeleton (ko04810);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Pancreatic secretion (ko04972);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Choline metabolism in cancer (ko05231);; Viral myocarditis (ko05416)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Ras-related C3 botulinum toxin substrate 1 (Precursor) GN=RAC1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras-related C3 botulinum toxin substrate 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000136240(KDELR2)	--	117.8410445	4444	115.3835597	4264	120.342402	4460	143.9998831	5450	137.8545883	5186	120.1774162	4500	0.972349161	0.263482779	normal	0.972455855	0.260904193	normal	0.992811386	0.0045883	normal	0.356553136	0.179260384	normal	--	--	Biological Process: protein retention in ER lumen (GO:0006621);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ER retention sequence binding (GO:0046923);; 	K10949|7.42997e-151|pon:100444603|KDELR2; KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2; K10949 ER lumen protein retaining receptor (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ER lumen protein retaining receptor	ER lumen protein-retaining receptor 2 GN=KDELR2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ER lumen protein retaining receptor 2 [Erinaceus europaeus]
ENSG00000136243(NUPL2)-2	--	11.38977	301	11.25519286	315	12.12600617	346	14.60519913	418	11.86846225	335	12.89057124	363	0.655741842	0.440989634	normal	0.965326237	0.06707045	normal	0.967240809	0.060647256	normal	0.502782233	0.192720477	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000136243(NUPL2)-3	--	0	0	0	0	0	0	4.3455	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000136244(IL6)	--	1.352358151	20	1.273689	18	3.263562338	42	7.190234705	105	4.54892844	74	8.4928946	156	4.47E-09	2.276983408	up	3.98E-05	1.931946884	up	4.91E-09	1.847862036	up	0.002399775	2.047607981	up	--	--	Molecular Function: interleukin-6 receptor binding (GO:0005138);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; 	"K05405|6.95451e-133|hsa:3569|IL6, BSF2, HGF, HSF, IFNB2, IL-6; interleukin 6; K05405 interleukin 6 (A)"	Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; Cytosolic DNA-sensing pathway (ko04623);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; TNF signaling pathway (ko04668);; Intestinal immune network for IgA production (ko04672);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Prion diseases (ko05020);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Malaria (ko05144);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323);; Graft-versus-host disease (ko05332);; Hypertrophic cardiomyopathy (HCM) (ko05410)	--	--	Interleukin-6/G-CSF/MGF family	Interleukin-6 (Precursor) GN=IL6 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: interleukin-6 [Galeopterus variegatus]
ENSG00000136247(ZDHHC4)	--	30.04435897	616	25.20269672	521	26.62034063	524	31.1813858	647	29.25064581	588	34.66275424	690	0.973535964	0.039905977	normal	0.960093295	0.152688851	normal	0.753169249	0.387759943	normal	0.403153133	0.191656298	normal	[R]	General function prediction only	--	"K18932|0|hsa:55146|ZDHHC4, ZNF374; zinc finger, DHHC-type containing 4 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC4 GN=ZDHHC4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC4 isoform X1 [Tupaia chinensis] 
ENSG00000136261(BZW2)	--	42.76557881	1390	37.79141111	1187	40.42847165	1304	45.885381	1488	42.52840777	1306	40.055811	1246	0.982129667	0.067385386	normal	0.976558332	0.11626715	normal	0.980461776	-0.073843625	normal	0.896143991	0.036224924	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	eIF4-gamma/eIF5/eIF2-epsilon	Basic leucine zipper and W2 domain-containing protein 2 GN=BZW2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: basic leucine zipper and W2 domain-containing protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000136267(DGKB)	--	0.041502895	3	0	0	0	0	0	0	0.013501285	0	0.051125546	5	--	--	--	--	--	--	--	--	--	--	--	--	[IR]	Lipid transport and metabolism;; General function prediction only	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|hsa:1607|DGKB, DAGK2, DGK, DGK-BETA; diacylglycerol kinase, beta 90kDa (EC:2.7.1.107); K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase N-terminus;; Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Diacylglycerol kinase beta GN=DGKB OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: diacylglycerol kinase beta isoform 1 [Odobenus rosmarus divergens]
ENSG00000136270(TBRG4)	--	42.54262154	1639	41.95782492	1680	46.387466	1840	47.84830732	1806	45.31751104	1750	41.308077	1558	0.981684526	0.109052367	normal	0.984641035	0.037434115	normal	0.952744246	-0.248080121	normal	0.902702768	-0.034065742	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; 	--	--	--	--	"FAST kinase-like protein, subdomain 2;; FAST kinase-like protein, subdomain 1;; RAP domain"	Protein TBRG4 GN=TBRG4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein TBRG4 [Galeopterus variegatus] 
ENSG00000136271(DDX56)	--	40.14948787	1705	41.50410438	1752	41.82941117	1757	45.858762	1897	45.7728911	1930	39.94349407	1688	0.98106316	0.123010557	normal	0.981450518	0.118074385	normal	0.984197613	-0.066032739	normal	0.813067828	0.059499215	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K14810|0|ggo:101142401|DDX56; probable ATP-dependent RNA helicase DDX56 isoform 1; K14810 ATP-dependent RNA helicase DDX56/DBP9 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Probable ATP-dependent RNA helicase DDX56 GN=DDX56 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX56 [Galeopterus variegatus]
ENSG00000136273(HUS1)	--	8.95189881	599	12.00540872	650	8.941786738	625	8.472298717	574	8.758794356	508	12.46744307	694	0.969512384	-0.092096179	normal	0.785335387	-0.376045341	normal	0.964776738	0.142460777	normal	0.720246401	-0.098176301	normal	--	--	Biological Process: DNA damage checkpoint (GO:0000077);; Cellular Component: checkpoint clamp complex (GO:0030896);; 	K10903|0|ptr:463402|HUS1; HUS1 checkpoint homolog (S. pombe); K10903 HUS1 checkpoint protein (A)	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Hus1-like protein	Checkpoint protein HUS1 GN=HUS1 OS=Homo sapiens (Human) PE=1 SV=1	DL	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	PREDICTED: checkpoint protein HUS1 isoform X1 [Equus caballus] 
ENSG00000136274(NACAD)	--	0.208138	23	0.0902454	10	0.131294	14	0.0730688	8	0.140733	15	0.0447606	5	0.791307961	-1.390784608	normal	--	--	--	--	--	--	--	--	--	[K]	Transcription	--	--	--	[K]	Transcription	NAC domain	NAC-alpha domain-containing protein 1 GN=NACAD OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	"NAC-alpha domain-containing protein 1, partial [Bos mutus]"
ENSG00000136279(DBNL)	--	35.7806444	2123	34.3256096	2178	36.88902532	2143	43.35414163	2440	40.0776775	2310	33.02917681	1987	0.978854538	0.169829804	normal	0.986577812	0.063419579	normal	0.983209448	-0.117245471	normal	0.874328069	0.042358511	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; 	--	--	[Z]	Cytoskeleton	Cofilin/tropomyosin-type actin-binding protein;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Drebrin-like protein GN=DBNL OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: drebrin-like protein isoform X1 [Galeopterus variegatus]
ENSG00000136280(CCM2)	--	25.63206013	946	23.78103498	907	26.24880778	990	22.33238826	834	22.28221249	805	20.46073196	767	0.952189436	-0.212257588	normal	0.957278563	-0.19319815	normal	0.780439403	-0.375839285	normal	0.16012779	-0.262085958	normal	--	--	--	--	--	--	--	Phosphotyrosine interaction domain (PTB/PID)	Malcavernin GN=CCM2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: malcavernin [Galeopterus variegatus]
ENSG00000136286(MYO1G)	--	0	0	0.0284655	2	0.0139253	0	0	0	0	0	0.0143896	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10356|0|hsa:64005|MYO1G, HA2, HLA-HA2, MHAG; myosin IG; K10356 myosin I (A)"	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail	Minor histocompatibility antigen HA-2 {ECO:0000303|PubMed:11544309} GN=MYO1G OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-Ig [Galeopterus variegatus]
ENSG00000136295(TTYH3)	--	57.32379267	5074	55.83701888	5007	59.22342838	5271	68.33968776	5952	73.8458357	6421	65.9381349	5842	0.98612537	0.199362963	normal	0.941562679	0.337334811	normal	0.990882521	0.14005604	normal	0.222832775	0.225586765	normal	--	--	--	--	--	[R]	General function prediction only	Tweety	Protein tweety homolog 3 GN=TTYH3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein tweety homolog 3 [Condylura cristata]
ENSG00000136305(CIDEB)	--	5.760928	152	5.567217	143	6.149198	156	7.278033003	192	6.358821	165	4.947434	127	0.91763743	0.30346844	normal	0.953842001	0.183219324	normal	0.926958795	-0.301760922	normal	0.880007499	0.079594208	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: apoptotic process (GO:0006915);; 	--	--	--	--	CIDE-N domain	Cell death activator CIDE-B GN=CIDEB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cell death activator CIDE-B [Eptesicus fuscus]
ENSG00000136319(TTC5)	--	6.042969509	469	5.961532578	465	6.549651453	481	4.901112074	382	5.442949939	412	5.605478277	419	0.866351472	-0.325662942	normal	0.947550304	-0.19533753	normal	0.94497865	-0.206681264	normal	0.312683427	-0.243058439	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 5 GN=TTC5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 5 [Condylura cristata]
ENSG00000136327(NKX2-8)	--	4.60058	69	3.92444	61	3.20145	51	3.17674	49	2.09285	32	3.61179	56	0.911416379	-0.511072226	normal	0.526060084	-0.920133579	normal	0.976246685	0.123152137	normal	0.47250479	-0.423140835	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09347|1.56718e-108|hsa:26257|NKX2-8, NKX2.8, NKX2H, Nkx2-9; NK2 homeobox 8; K09347 homeobox protein Nkx-2.8 (A)"	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-2.8 GN=NKX2-8 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein Nkx-2.8 [Oryctolagus cuniculus]
ENSG00000136352(NKX2-1)	--	0.084445266	3	0	0	0	0	0.084158888	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09342|1.07552e-174|hsa:7080|NKX2-1, BCH, BHC, NK-2, NKX2.1, NKX2A, T/EBP, TEBP, TITF1, TTF-1, TTF1; NK2 homeobox 1; K09342 homeobox protein Nkx-2.1 (A)"	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-2.1 GN=NKX2-1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: thyroid transcription factor 1-like isoformX1 [Sus scrofa]
ENSG00000136367(ZFHX2)	--	1.4390532	250	1.270927966	256	1.668512144	331	1.112122222	235	0.805309	173	1.1366013	224	0.960926493	-0.119342911	normal	0.364038433	-0.582583453	normal	0.306578761	-0.568446394	normal	0.108537725	-0.426284796	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K09379|0|hsa:85446|ZFHX2, ZFH-5, ZNF409; zinc finger homeobox 2; K09379 zinc finger homeobox protein 2 (A)"	--	[R]	General function prediction only	Homeobox domain;; C2H2 type zinc-finger (2 copies);; Homeobox KN domain	Zinc finger homeobox protein 2 GN=ZFHX2 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger homeobox protein 2 [Galeopterus variegatus]
ENSG00000136371(MTHFS)	--	48.55979765	953	44.4295598	1027	48.86925148	1108	50.6463801	1206	46.96951701	1117	56.41447064	1283	0.895660507	0.308406699	normal	0.97604686	0.099625754	normal	0.960956944	0.203014135	normal	0.2878226	0.202875092	normal	[H]	Coenzyme transport and metabolism	--	K01934|5.33178e-108|hsa:100528021|ST20-MTHFS; ST20-MTHFS readthrough; K01934 5-formyltetrahydrofolate cyclo-ligase [EC:6.3.3.2] (A)	One carbon pool by folate (ko00670)	[H]	Coenzyme transport and metabolism	5-formyltetrahydrofolate cyclo-ligase family	5-formyltetrahydrofolate cyclo-ligase GN=MTHFS OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: 5-formyltetrahydrofolate cyclo-ligase isoform X1 [Tupaia chinensis]
ENSG00000136378(ADAMTS7)	--	4.184277441	381	2.604696376	298	3.043550002	352	4.761157876	508	5.368535987	580	3.676779643	390	0.776187236	0.382864244	normal	9.23E-05	0.935849875	normal	0.959557621	0.139039531	normal	0.068931006	0.497933531	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08622|0|hsa:11173|ADAMTS7, ADAM-TS_7, ADAM-TS7, ADAMTS-7; ADAM metallopeptidase with thrombospondin type 1 motif, 7 (EC:3.4.24.-); K08622 a disintegrin and metalloproteinase with thrombospondin motifs 7 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Thrombospondin type 1 domain;; Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 7 (Precursor) GN=ADAMTS7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 7 [Ceratotherium simum simum]
ENSG00000136379(ABHD17C)	--	17.30479967	534	14.6856275	455	16.26086275	473	21.60731239	644	19.96573423	618	18.560857	571	0.934345906	0.23876243	normal	0.683904309	0.419114286	normal	0.920360741	0.262593932	normal	0.139971855	0.304677423	normal	[R]	General function prediction only	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; 	--	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Prolyl oligopeptidase family;; Dienelactone hydrolase family	Alpha/beta hydrolase domain-containing protein 17C GN=ABHD17C OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	alpha/beta hydrolase domain-containing protein 17C [Bos taurus] 
ENSG00000136381(IREB2)	--	34.90333537	2947	30.68883036	3011	30.90148099	2962	31.41317343	3111	33.52127086	3288	29.27453089	2868	0.989856014	0.047275082	normal	0.987926927	0.105490321	normal	0.989390764	-0.054789629	normal	0.902537736	0.033667058	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; 	--	--	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	Aconitase family (aconitate hydratase);; Aconitase C-terminal domain	Iron-responsive element-binding protein 2 GN=IREB2 OS=Homo sapiens (Human) PE=1 SV=3	AJ	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	PREDICTED: iron-responsive element-binding protein 2 [Ovis aries]
ENSG00000136383(ALPK3)	--	0.187613	46	0.20784	52	0.189027	47	0.114542	28	0.174731	42	0.206301	51	0.89144386	-0.716069401	normal	0.966055804	-0.319198799	normal	0.977922379	0.106262017	normal	0.693737403	-0.280558358	normal	--	--	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08868|0|hsa:57538|ALPK3, MAK, MIDORI; alpha-kinase 3; K08868 alpha-kinase (A)"	--	--	--	Alpha-kinase family;; Immunoglobulin I-set domain;; Immunoglobulin domain	Alpha-protein kinase 3 GN=ALPK3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: alpha-protein kinase 3 [Galeopterus variegatus]
ENSG00000136404(TM6SF1)	--	0	0	0.21016424	5	0.0931382	1	0	0	0.19512	1	0.103367446	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF2781)	Transmembrane 6 superfamily member 1 GN=TM6SF1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane 6 superfamily member 1 [Physeter catodon] 
ENSG00000136425(CIB2)	--	17.25971565	452	11.71952972	295	16.102264	391	13.18379499	321	15.650093	379	11.33272406	271	0.364142049	-0.522462859	normal	0.859849816	0.338521807	normal	0.363755163	-0.534668997	normal	0.511245375	-0.250316916	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[R]	General function prediction only	EF-hand domain pair;; EF hand;; EF-hand domain	Calcium and integrin-binding family member 2 GN=CIB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: calcium and integrin-binding family member 2 isoform X1 [Galeopterus variegatus]
ENSG00000136436(CALCOCO2)	--	27.9173042	1577	26.16680885	1552	28.95220371	1629	32.55726026	1655	36.09528952	1764	31.55597849	1769	0.984362998	0.038779412	normal	0.974888219	0.163146257	normal	0.981442809	0.110557487	normal	0.639548205	0.103931104	normal	--	--	--	--	--	--	--	Calcium binding and coiled-coil domain (CALCOCO1) like	Calcium-binding and coiled-coil domain-containing protein 2 GN=CALCOCO2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: calcium-binding and coiled-coil domain-containing protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000136444(RSAD1)	--	25.089658	1113	20.468999	952	22.598289	1048	22.673474	1031	21.4676486	959	19.947808	908	0.971829479	-0.141039157	normal	0.978503568	-0.010840159	normal	0.953286317	-0.214832598	normal	0.579285972	-0.124767774	normal	[H]	Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	--	--	--	--	Radical SAM superfamily;; HemN C-terminal domain	"Radical S-adenosyl methionine domain-containing protein 1, mitochondrial (Precursor) GN=RSAD1 OS=Homo sapiens (Human) PE=2 SV=2"	R	General function prediction only	"PREDICTED: radical S-adenosyl methionine domain-containing protein 1, mitochondrial [Orcinus orca]"
ENSG00000136448(NMT1)	--	33.64495214	3389	33.92629759	3435	34.20933302	3449	35.57124956	3569	34.31922341	3426	35.65651923	3585	0.990927483	0.043808647	normal	0.990792674	-0.025200396	normal	0.99092452	0.047483126	normal	0.946424734	0.021306579	normal	[I]	Lipid transport and metabolism	Molecular Function: glycylpeptide N-tetradecanoyltransferase activity (GO:0004379);; 	K00671|0|ptr:454744|NMT1; N-myristoyltransferase 1; K00671 glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97] (A)	--	[I]	Lipid transport and metabolism	"Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain;; Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain"	Glycylpeptide N-tetradecanoyltransferase 1 GN=NMT1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: glycylpeptide N-tetradecanoyltransferase 1 [Ceratotherium simum simum]
ENSG00000136449(MYCBPAP)	--	0.929704492	54	0.798224998	53	0.66071488	40	0.45248593	17	0.313174581	22	0.471382859	23	0.011069488	-1.612196928	normal	0.17964435	-1.233606895	normal	0.898986361	-0.767917942	normal	0.015044406	-1.266214343	normal	--	--	--	--	--	--	--	MYCBP-associated protein family	MYCBP-associated protein OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: MYCBP-associated protein [Galeopterus variegatus]
ENSG00000136450(SRSF1)	--	178.8635161	7120	179.0981927	7109	186.5001452	7506	191.5979002	7649	220.101157	8340	167.6592095	6314	0.994650754	0.072546538	normal	0.988319152	0.208933121	normal	0.97969078	-0.257724781	normal	0.963328803	0.015672331	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12890|5.02064e-94|ptr:468417|SRSF1, SFRS1; serine/arginine-rich splicing factor 1; K12890 splicing factor, arginine/serine-rich 1/9 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Serine/arginine-rich splicing factor 1 GN=SRSF1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 1 isoform X1 [Erinaceus europaeus]
ENSG00000136451(VEZF1)	--	26.96895564	1979	27.70505616	2014	26.13344427	1877	29.68479458	2112	28.7761303	2095	32.20789033	2318	0.986031043	0.062958641	normal	0.986460301	0.035433915	normal	0.931547958	0.295945534	normal	0.525413809	0.131581696	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain"	Vascular endothelial zinc finger 1 GN=VEZF1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: vascular endothelial zinc finger 1 [Condylura cristata]
ENSG00000136457(CHAD)	--	0.324143991	10	0.457857728	14	0.398577427	12	0.2774684	9	0.5655846	18	0.095910248	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06248|0|hsa:1101|CHAD, SLRR4A; chondroadherin; K06248 chondroadherin (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512)	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeat;; Leucine rich repeat N-terminal domain;; Leucine rich repeat	Chondroadherin (Precursor) GN=CHAD OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: chondroadherin [Canis lupus familiaris]
ENSG00000136463(TACO1)	--	25.807	764	26.5143	799	28.7425	863	30.8986	924	31.7329	936	30.5554	908	0.938173671	0.243042995	normal	0.953543828	0.206525013	normal	0.976530299	0.064929363	normal	0.426352095	0.169208914	normal	[S]	Function unknown	--	"K18189|3.37802e-177|ptr:738517|CCDC44, TACO1; translational activator of cytochrome c oxidase 1; K18189 translational activator of cytochrome c oxidase 1 (A)"	--	[S]	Function unknown	Transcriptional regulator	Translational activator of cytochrome c oxidase 1 GN=TACO1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: translational activator of cytochrome c oxidase 1-like [Mustela putorius furo] 
ENSG00000136478(TEX2)	--	8.114039655	865	6.905063683	733	7.987357126	850	7.832512462	833	7.229933668	764	6.448319556	690	0.974632273	-0.085061919	normal	0.975028635	0.038255573	normal	0.887166895	-0.308547474	normal	0.621092743	-0.119757594	normal	--	--	--	--	--	[R]	General function prediction only	Putative integral membrane protein conserved region (DUF2404)	Testis-expressed sequence 2 protein GN=TEX2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: testis-expressed sequence 2 protein isoform X1 [Tupaia chinensis]
ENSG00000136485(DCAF7)	--	28.7331151	2758	26.81493017	2633	28.92438481	2741	33.02323187	3304	32.47754335	3404	31.26859754	3046	0.972027992	0.229641964	normal	0.899021931	0.348920278	normal	0.984766767	0.143846854	normal	0.164454006	0.241031484	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11805|0|umr:103665626|DCAF7; DDB1 and CUL4 associated factor 7; K11805 WD repeat-containing protein 68 (A)	--	[S]	Function unknown	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 7 GN=DCAF7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"DDB1- and CUL4-associated factor 7, partial [Bos mutus]"
ENSG00000136490(LIMD2)	--	10.770941	262	8.72985	254	7.05945	230	10.501938	249	11.726453	290	6.955529	176	0.962564365	-0.103629842	normal	0.952269248	0.168856448	normal	0.834625269	-0.391398915	normal	0.851244931	-0.08338596	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	LIM domain-containing protein 2 GN=LIMD2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LIM domain-containing protein 2 [Camelus ferus] 
ENSG00000136492(BRIP1)	--	6.285497521	643	6.98511	660	7.001573397	721	7.26905148	789	8.00014608	816	6.3698182	655	0.923160084	0.263804469	normal	0.910119589	0.284090211	normal	0.964672427	-0.146473325	normal	0.564429106	0.137626508	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Molecular Function: ATP binding (GO:0005524);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: ATP-dependent helicase activity (GO:0008026);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; "	"K15362|0|hsa:83990|BRIP1, BACH1, FANCJ, OF; BRCA1 interacting protein C-terminal helicase 1 (EC:3.6.4.13); K15362 fanconi anemia group J protein [EC:3.6.4.12] (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	Helicase C-terminal domain;; DEAD_2;; DEAD/DEAH box helicase	Fanconi anemia group J protein GN=BRIP1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: Fanconi anemia group J protein [Galeopterus variegatus]
ENSG00000136504(KAT7)	--	16.44308003	1142	17.81485	1209	18.79629305	1216	16.61910818	1157	16.76732	1192	18.77779	1315	0.981095139	-0.011990024	normal	0.980610049	-0.041803904	normal	0.978270651	0.104503124	normal	0.958484282	0.017950155	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K11307|0|pon:100457486|KAT7; K(lysine) acetyltransferase 7; K11307 histone acetyltransferase MYST2 [EC:2.3.1.48] (A)	--	[B]	Chromatin structure and dynamics	"MOZ/SAS family;; Zinc finger, C2HC type"	Histone acetyltransferase KAT7 GN=KAT7 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase KAT7 [Pteropus alecto] 
ENSG00000136518(ACTL6A)	--	27.41888631	859	28.223757	901	27.46160367	854	29.89237713	951	27.05891562	851	26.754703	849	0.972607411	0.11575812	normal	0.972993543	-0.103615548	normal	0.977647126	-0.016733239	normal	1	-0.001350898	normal	[Z]	Cytoskeleton	--	K11340|0|pps:100968810|ACTL6A; actin-like 6A; K11340 actin-like protein 6A (A)	--	[Z]	Cytoskeleton	Actin	Actin-like protein 6A GN=ACTL6A OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: actin-like protein 6A [Oryctolagus cuniculus]
ENSG00000136521(NDUFB5)	--	36.92121508	546	36.86131574	559	37.41484132	546	40.42865972	623	35.46656628	538	36.49205959	536	0.96002024	0.159079676	normal	0.969398979	-0.076457806	normal	0.97211853	-0.034861935	normal	0.964587023	0.017929236	normal	--	--	--	"K03961|7.39834e-109|ptr:471008|NDUFB5; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa; K03961 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 5 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial (Precursor) GN=NDUFB5 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial isoform X1 [Ochotona princeps]"
ENSG00000136522(MRPL47)	--	16.45217	302	16.057515	307	15.028002	269	16.033773	313	17.61796	337	16.73203024	308	0.967742737	0.020678509	normal	0.96133216	0.112554068	normal	0.949637341	0.186054547	normal	0.769218868	0.104392961	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: mitochondrial ribosome (GO:0005761);; Biological Process: translation (GO:0006412);; 	"K17428|9.9356e-170|hsa:57129|MRPL47, L47mt, MRP-L47, NCM1; mitochondrial ribosomal protein L47; K17428 large subunit ribosomal protein L47 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial 39-S ribosomal protein L47 (MRP-L47)	"39S ribosomal protein L47, mitochondrial (Precursor) GN=MRPL47 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L47, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000136527(TRA2B)	--	55.33608196	2258	54.003731	2265	57.947634	2408	60.43627854	2659	61.3096356	2517	54.96459809	2302	0.973961644	0.204877457	normal	0.983495608	0.13068481	normal	0.987012552	-0.073191983	normal	0.699842325	0.088086844	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12897|4.41422e-71|ptr:460905|TRA2B, SFRS10; transformer 2 beta homolog (Drosophila); K12897 transformer-2 protein (A)"	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Transformer-2 protein homolog beta GN=TRA2B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	hypothetical protein PANDA_003724 [Ailuropoda melanoleuca]
ENSG00000136531(SCN2A)	--	0.116785084	18	0.105914444	16	0.14436717	13	0.423354064	44	0.435579785	42	0.478783883	53	0.442804971	1.191752909	normal	0.333490576	1.292926355	normal	0.001524456	1.901562082	up	0.003573565	1.543261192	up	--	--	Cellular Component: voltage-gated sodium channel complex (GO:0001518);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated sodium channel activity (GO:0005248);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04834|0|hsa:6326|SCN2A, BFIC3, BFIS3, BFNIS, EIEE11, HBA, HBSCI, HBSCII, NAC2, Na(v)1.2, Nav1.2, SCN2A1, SCN2A2; sodium channel, voltage-gated, type II, alpha subunit; K04834 voltage-gated sodium channel type II alpha (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Sodium ion transport-associated;; Domain of unknown function (DUF3451);; Polycystin cation channel	Sodium channel protein type 2 subunit alpha GN=SCN2A OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel protein type 2 subunit alpha isoform X1 [Galeopterus variegatus] 
ENSG00000136535(TBR1)	--	0.01677626	1	0	0	0	0	0	0	0.103401836	2	0.016479142	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10174|0|ptr:739449|TBR1; T-box, brain, 1; K10174 T-box brain protein 1 (A)"	--	[K]	Transcription	T-box	T-box brain protein 1 GN=TBR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: T-box brain protein 1 [Elephantulus edwardii]
ENSG00000136536(MARCH7)	--	29.63224559	1881	35.496042	2103	32.363029	1986	23.48987	1437	20.693592	1290	23.6226845	1377	0.683440262	-0.418879232	normal	0.003257733	-0.725830878	normal	0.199947573	-0.536135392	normal	8.73E-05	-0.562090171	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10662|0|ptr:459681|MARCH7; membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase; K10662 E3 ubiquitin-protein ligase MARCH7 [EC:6.3.2.19] (A)"	--	[A]	RNA processing and modification	RING-variant domain	E3 ubiquitin-protein ligase MARCH7 GN=MARCH7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MARCH7 isoform X1 [Felis catus]
ENSG00000136542(GALNT5)	--	1.610072251	169	1.546176826	158	1.823333562	193	7.058714085	864	5.771502521	673	5.518734968	628	0	2.312848241	up	0	2.058876177	up	5.55E-16	1.686123988	up	8.96E-16	2.035866913	up	--	--	--	"K00710|0|hsa:11227|GALNT5, GALNAC-T5, GALNACT5; polypeptide N-acetylgalactosaminyltransferase 5 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; N-terminal domain of galactosyltransferase	Polypeptide N-acetylgalactosaminyltransferase 5 GN=GALNT5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 5 [Equus caballus]
ENSG00000136560(TANK)	--	18.52880297	629	20.84635211	679	20.806876	622	18.46062216	618	18.9591483	614	20.63916448	716	0.972710559	-0.056147074	normal	0.959421637	-0.166209982	normal	0.953373004	0.194312898	normal	0.985893701	-0.007476597	normal	--	--	--	"K12650|0|hsa:10010|TANK, I-TRAF, ITRAF, TRAF2; TRAF family member-associated NFKB activator; K12650 TRAF family member-associated NF-kappa-B activator (A)"	RIG-I-like receptor signaling pathway (ko04622)	--	--	TBD domain	TRAF family member-associated NF-kappa-B activator GN=TANK OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: TRAF family member-associated NF-kappa-B activator isoform X1 [Galeopterus variegatus]
ENSG00000136573(BLK)	--	0	0	0	0	0	0	0	0	0	0	0.026171462	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08890|0|hsa:640|BLK, MODY11; BLK proto-oncogene, Src family tyrosine kinase (EC:2.7.10.2); K08890 B lymphoid tyrosine kinase [EC:2.7.10.2] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Tyrosine-protein kinase Blk GN=BLK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase Blk [Eptesicus fuscus]
ENSG00000136574(GATA4)	--	1.736474311	93	1.592684717	84	1.437265125	88	1.092915146	67	1.215364816	72	1.014898107	63	0.876055059	-0.494235197	normal	0.959950558	-0.239163029	normal	0.893138781	-0.480635977	normal	0.397851982	-0.412940162	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	K09183|0|pon:100441924|GATA4; GATA binding protein 4; K09183 GATA-binding protein 4 (A)	cGMP-PKG signaling pathway (ko04022);; Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	"GATA-type transcription activator, N-terminal;; GATA zinc finger"	Transcription factor GATA-4 GN=GATA4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor GATA-4 isoform X1 [Orycteropus afer afer]
ENSG00000136603(SKIL)	--	16.24002218	1695	18.85252607	1897	12.75692465	1326	18.504613	2008	23.82312535	2477	19.8570612	1990	0.96660022	0.2134638	normal	0.858463803	0.363193587	normal	0.094731862	0.576855595	normal	0.126096839	0.375169782	normal	--	--	Molecular Function: SMAD binding (GO:0046332);; 	K18499|0|pps:100979585|SKIL; SKI-like proto-oncogene; K18499 Ski-like protein (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	--	--	c-SKI Smad4 binding domain;; SKI/SNO/DAC family	Ski-like protein GN=SKIL OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ski-like protein isoform 2 [Odobenus rosmarus divergens] 
ENSG00000136628(EPRS)	--	47.399948	5090	47.80959	5147	47.92337	5079	38.58095	4166	34.897903	3748	49.4118969	5326	0.94421067	-0.319728187	normal	0.570615798	-0.47887175	normal	0.993113736	0.060199007	normal	0.286504542	-0.230646799	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: proline-tRNA ligase activity (GO:0004827);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; Biological Process: prolyl-tRNA aminoacylation (GO:0006433);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	"K14163|0|hsa:2058|EPRS, EARS, GLUPRORS, PARS, QARS, QPRS; glutamyl-prolyl-tRNA synthetase (EC:6.1.1.15 6.1.1.17); K14163 bifunctional glutamyl/prolyl-tRNA synthetase [EC:6.1.1.17 6.1.1.15] (A)"	Porphyrin and chlorophyll metabolism (ko00860);; Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (E and Q), catalytic domain;; WHEP-TRS domain;; tRNA synthetases class I (E and Q), anti-codon binding domain;; Prolyl-tRNA synthetase, C-terminal;; tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain"	Proline--tRNA ligase GN=EPRS OS=Homo sapiens (Human) PE=1 SV=5	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: bifunctional glutamate/proline--tRNA ligase isoform 1 [Equus caballus]
ENSG00000136630(HLX)	--	1.848548818	67	1.89405	43	1.599417725	60	4.37297734	160	4.566903431	168	4.100977099	152	0.000334506	1.206575996	up	6.85E-10	1.908147277	up	8.40E-05	1.311258913	up	2.94E-06	1.476446458	up	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09339|0|hsa:3142|HLX, HB24, HLX1; H2.0-like homeobox; K09339 homeobox protein HLX1 (A)"	--	[R]	General function prediction only	Homeobox domain	H2.0-like homeobox protein GN=HLX OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: H2.0-like homeobox protein [Equus przewalskii]
ENSG00000136631(VPS45)	--	9.774862595	499	8.036995775	396	9.92356002	485	11.5462583	563	11.45088862	588	9.2938396	475	0.96190817	0.142848604	normal	0.252020986	0.547164107	normal	0.970792568	-0.038228225	normal	0.362357454	0.215234518	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K12479|0|pps:100983204|VPS45; vacuolar protein sorting 45 homolog (S. cerevisiae); K12479 vacuolar protein sorting-associated protein 45 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec1 family	Vacuolar protein sorting-associated protein 45 GN=VPS45 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	vacuolar protein sorting-associated protein 45 [Sus scrofa]
ENSG00000136636(KCTD3)	--	21.95230766	1462	23.09383839	1554	22.89114019	1483	22.52672068	1556	22.729461	1568	18.546077	1282	0.983011837	0.059006375	normal	0.984057057	-0.008479288	normal	0.959269811	-0.218174261	normal	0.844804995	-0.051881801	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD3 GN=KCTD3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD3 isoform 1 [Orcinus orca]
ENSG00000136643(RPS6KC1)	--	7.428919313	625	7.417917553	660	7.373232479	638	7.74793475	674	8.140453172	698	5.585634819	475	0.971846575	0.077875769	normal	0.972975348	0.059202539	normal	0.629630548	-0.432727143	normal	0.809168413	-0.080271554	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	--	--	[T]	Signal transduction mechanisms	Protein kinase domain;; MIT (microtubule interacting and transport) domain;; PX domain;; Protein tyrosine kinase	Ribosomal protein S6 kinase delta-1 GN=RPS6KC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ribosomal protein S6 kinase delta-1 isoform 1 [Canis lupus familiaris]
ENSG00000136682(CBWD2)	--	7.33844284	221	7.406427485	225	8.453194743	243	7.794380879	232	6.736458893	201	8.037988677	242	0.966402609	0.038981666	normal	0.950450847	-0.182854897	normal	0.967052509	-0.01415245	normal	0.912431504	-0.050592685	normal	[R]	General function prediction only	--	--	--	[H]	Coenzyme transport and metabolism	"CobW/HypB/UreG, nucleotide-binding domain;; Cobalamin synthesis protein cobW C-terminal domain"	COBW domain-containing protein 2 GN=CBWD2 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: COBW domain-containing protein 2 isoform X4 [Canis lupus familiaris]
ENSG00000136689(IL1RN)	--	0	0	0	0	0	0	0	0	0	0	0.034348058	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular space (GO:0005615);; Biological Process: inflammatory response (GO:0006954);; Biological Process: immune response (GO:0006955);; 	"K05481|9.50564e-115|hsa:3557|IL1RN, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4; interleukin 1 receptor antagonist; K05481 interleukin 1 receptor antagonist (A)"	--	--	--	Interleukin-1 / 18	Interleukin-1 receptor antagonist protein (Precursor) GN=IL1RN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor antagonist protein [Condylura cristata]
ENSG00000136695(IL36RN)	--	0	0	0	0	0	0	0	0	0	0	0.02020824	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular space (GO:0005615);; Biological Process: inflammatory response (GO:0006954);; Biological Process: immune response (GO:0006955);; 	"K05483|7.28184e-112|hsa:26525|IL36RN, FIL1, FIL1(DELTA), FIL1D, IL-36Ra, IL1F5, IL1HY1, IL1L1, IL1RP3, IL36RA, PSORP, PSORS14; interleukin 36 receptor antagonist; K05483 interleukin 1 family, member 5 (delta) (A)"	--	--	--	Interleukin-1 / 18	Interleukin-36 receptor antagonist protein GN=UNQ1896/PRO4342 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-36 receptor antagonist protein isoform X2 [Canis lupus familiaris] 
ENSG00000136696(IL36B)	--	0.072509	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05486|1.33686e-119|hsa:27177|IL36B, FIL1, FIL1-(ETA), FIL1H, FILI-(ETA), IL-1F8, IL-1H2, IL1-ETA, IL1F8, IL1H2; interleukin 36, beta; K05486 interleukin 1 family, member 8 (eta) (A)"	--	--	--	--	Interleukin-36 beta (Precursor) GN=IL36B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: interleukin-36 beta [Galeopterus variegatus]
ENSG00000136699(SMPD4)	--	35.25624319	2509	36.11522464	2532	38.87713181	2768	27.94811391	1906	26.76429748	1863	26.84618193	1936	0.678539235	-0.427095453	normal	0.54981643	-0.463751994	normal	0.259596535	-0.523712422	normal	0.001206818	-0.473894156	normal	--	--	Molecular Function: sphingomyelin phosphodiesterase D activity (GO:0050290);; 	K12353|0|ptr:459619|SMPD4; sphingomyelin phosphodiesterase 4; K12353 sphingomyelin phosphodiesterase 4 [EC:3.1.4.12] (A)	Sphingolipid metabolism (ko00600)	[S]	Function unknown	Mitochondrial-associated sphingomyelin phosphodiesterase	Sphingomyelin phosphodiesterase 4 GN=SMPD4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: sphingomyelin phosphodiesterase 4 isoform X1 [Galeopterus variegatus]
ENSG00000136709(WDR33)	--	32.2237852	2588	31.765989	2737	36.30329531	2762	25.22155366	2274	25.29800436	2176	25.7956993	2136	0.97096436	-0.217299876	normal	0.882807237	-0.352124695	normal	0.829151832	-0.378856554	normal	0.047347167	-0.317530873	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K15542|0|pps:100968909|WDR33; WD repeat domain 33; K15542 polyadenylation factor subunit 2 (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"WD domain, G-beta repeat;; Collagen triple helix repeat (20 copies);; Eukaryotic translation initiation factor eIF2A"	pre-mRNA 3' end processing protein WDR33 GN=WDR33 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: pre-mRNA 3' end processing protein WDR33 isoform X1 [Camelus dromedarius]
ENSG00000136710(CCDC115)	--	15.5447	441	13.945879	407	16.09819	455	10.43546	290	10.243711	289	11.66376	312	0.08981612	-0.632817466	normal	0.436483949	-0.513111416	normal	0.274323447	-0.550389414	normal	0.005914622	-0.569173936	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 115 GN=CCDC115 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 115-like [Sus scrofa]
ENSG00000136715(SAP130)	--	10.94309948	941	10.9845032	919	11.7748081	1007	7.320473	626	7.3579509	640	7.30723333	536	0.050718032	-0.61761852	normal	0.214679937	-0.542343782	normal	2.33E-05	-0.916132582	normal	8.71E-06	-0.691387422	normal	--	--	--	--	--	--	--	--	Histone deacetylase complex subunit SAP130 GN=SAP130 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone deacetylase complex subunit SAP130 isoform X1 [Galeopterus variegatus]
ENSG00000136717(BIN1)	--	21.95354903	883	17.92434561	735	20.254618	854	12.60783513	570	13.09611883	600	10.80549265	467	0.02166567	-0.660840102	normal	0.88103167	-0.313493011	normal	0.000106521	-0.876972421	normal	0.000165535	-0.616176065	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	BAR domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Myc box-dependent-interacting protein 1 GN=BIN1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: myc box-dependent-interacting protein 1 isoform X9 [Mustela putorius furo] 
ENSG00000136718(IMP4)	--	48.45505485	1478	43.40789585	1403	50.68211066	1478	37.43856325	1197	41.6785669	1210	28.18477206	991	0.871150461	-0.33466794	normal	0.952137995	-0.234661858	normal	0.083100605	-0.584245697	normal	0.01586663	-0.380943729	normal	[JA]	"Translation, ribosomal structure and biogenesis;; RNA processing and modification"	--	"K14561|0|hsa:92856|IMP4, BXDC4; IMP4, U3 small nucleolar ribonucleoprotein; K14561 U3 small nucleolar ribonucleoprotein protein IMP4 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	Brix domain	U3 small nucleolar ribonucleoprotein protein IMP4 GN=IMP4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U3 small nucleolar ribonucleoprotein protein IMP4 [Oryctolagus cuniculus]
ENSG00000136720(HS6ST1)	--	18.96882249	951	15.42661009	806	16.6734467	909	9.539475535	449	7.02573615	402	10.4127922	505	4.60E-08	-1.110885246	down	2.45E-06	-1.022237946	down	0.000174184	-0.854353396	normal	1.41E-10	-0.996112552	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	K02514|0|ptr:470530|HS6ST1; heparan sulfate 6-O-sulfotransferase 1; K02514 heparan sulfate 6-O-sulfotransferase HS6ST1 [EC:2.8.2.-] (A)	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	Sulfotransferase family	Heparan-sulfate 6-O-sulfotransferase 1 GN=HS6ST1 OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan-sulfate 6-O-sulfotransferase 1 [Odobenus rosmarus divergens]
ENSG00000136731(UGGT1)	--	23.03939	4698	20.77474	4237	21.93468	4409	16.20965	3304	16.90421	3420	14.30973	2911	0.242117648	-0.538454091	normal	0.930294763	-0.330341841	normal	0.058610363	-0.606969968	normal	0.000910383	-0.491346479	normal	--	--	Molecular Function: UDP-glucose:glycoprotein glucosyltransferase activity (GO:0003980);; Biological Process: protein glycosylation (GO:0006486);; 	"K11718|0|hsa:56886|UGGT1, HUGT1, UGCGL1, UGT1; UDP-glucose glycoprotein glucosyltransferase 1; K11718 UDP-glucose:glycoprotein glucosyltransferase [EC:2.4.1.-] (A)"	Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	UDP-glucose:Glycoprotein Glucosyltransferase	UDP-glucose:glycoprotein glucosyltransferase 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucose:glycoprotein glucosyltransferase 1 isoform X1 [Galeopterus variegatus]
ENSG00000136738(STAM)	--	13.762761	688	15.69870604	776	17.56592354	862	16.44931371	825	13.82683834	692	14.79490974	741	0.941921285	0.230682359	normal	0.956549654	-0.18632639	normal	0.945199422	-0.226077544	normal	0.821676867	-0.064115147	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; 	"K04705|0|hsa:8027|STAM, STAM-1, STAM1; signal transducing adaptor molecule (SH3 domain and ITAM motif) 1; K04705 signal transducing adaptor molecule (A)"	Endocytosis (ko04144);; Jak-STAT signaling pathway (ko04630)	[T]	Signal transduction mechanisms	VHS domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Ubiquitin interaction motif	Signal transducing adapter molecule 1 GN=STAM OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: signal transducing adapter molecule 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000136754(ABI1)	--	18.51197937	951	19.69328696	993	17.84882427	949	20.08218951	1053	18.44330659	949	19.41693039	980	0.973977364	0.115977816	normal	0.975775532	-0.086677141	normal	0.978655429	0.038022593	normal	0.946746066	0.022219321	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Abl-interactor HHR;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Abl interactor 1 GN=ABI1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: abl interactor 1 isoform 1 [Ceratotherium simum simum]
ENSG00000136758(YME1L1)	--	62.63363835	3940	63.38414608	4257	66.03250041	4214	62.65291313	4187	61.96563606	4070	60.507979	3985	0.991733129	0.056867512	normal	0.990907578	-0.08620353	normal	0.990941365	-0.088869231	normal	0.883063834	-0.041083991	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metalloendopeptidase activity (GO:0004222);; Molecular Function: ATP binding (GO:0005524);; Biological Process: proteolysis (GO:0006508);; 	K08955|0|ggo:101149193|YME1L1; ATP-dependent zinc metalloprotease YME1L1; K08955 ATP-dependent metalloprotease [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M41;; ATPase family associated with various cellular activities (AAA)	ATP-dependent zinc metalloprotease YME1L1 GN=YME1L1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	ATP-dependent zinc metalloprotease YME1L1 [Bos mutus]
ENSG00000136770(DNAJC1)	--	16.97969	689	16.73655	621	16.8601283	716	19.322	755	23.67719	905	21.05487	843	0.971182995	0.100925364	normal	0.289797607	0.520841599	normal	0.94437109	0.226839595	normal	0.135588077	0.284407798	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09521|0|hsa:64215|DNAJC1, DNAJL1, ERdj1, HTJ1, MTJ1; DnaJ (Hsp40) homolog, subfamily C, member 1; K09521 DnaJ homolog subfamily C member 1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain	DnaJ homolog subfamily C member 1 (Precursor) GN=DNAJC1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 1-like [Elephantulus edwardii]
ENSG00000136783(NIPSNAP3A)	--	11.8879	242	14.0632	287	15.1071	304	14.939	309	13.076	266	14.2765	292	0.885984466	0.319966132	normal	0.958580188	-0.130337443	normal	0.965956927	-0.066059065	normal	0.937849443	0.036512345	normal	--	--	--	--	--	[S]	Function unknown	NIPSNAP	Protein NipSnap homolog 3A GN=NIPSNAP3A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein NipSnap homolog 3A [Oryctolagus cuniculus]
ENSG00000136802(LRRC8A)	--	12.2582172	1092	13.89381603	1248	14.55110742	1322	25.650526	2283	23.784723	2108	20.20946532	1817	1.04E-07	1.032099895	up	0.002670034	0.734138489	normal	0.558851731	0.450103827	normal	1.98E-07	0.739833942	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine-rich repeat containing protein 8;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies)	Volume-regulated anion channel subunit LRRC8A GN=LRRC8A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 8A [Galeopterus variegatus]
ENSG00000136807(CDK9)	--	25.41394	1454	20.95367	1230	24.32344	1352	22.698127	1389	25.975687	1526	23.05392	1301	0.980291194	-0.096708362	normal	0.92314438	0.289350166	normal	0.981419347	-0.063692999	normal	0.880705945	0.041685136	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02211|0|ptr:464755|CDK9; cyclin-dependent kinase 9; K02211 cyclin-dependent kinase 9 [EC:2.7.11.22 2.7.11.23] (A)	Transcriptional misregulation in cancer (ko05202)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 9 GN=CDK9 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	cell division protein kinase 9 [Sus scrofa] 
ENSG00000136810(TXN)	--	573.469549	6464	715.5230001	8208	636.767991	7241	713.83562	8093	593.306782	6643	692.740523	7807	0.970886253	0.293352712	normal	0.957738913	-0.326555354	normal	0.994136273	0.100267705	normal	0.954684329	0.019431679	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Cellular Component: spliceosomal complex (GO:0005681);; Biological Process: cell redox homeostasis (GO:0045454);; "	K03671|1.07812e-70|ptr:740248|TXN; thioredoxin; K03671 thioredoxin 1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like;; Thioredoxin-like domain;; Mitosis protein DIM1	Thioredoxin GN=TXN OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: thioredoxin [Galeopterus variegatus]
ENSG00000136811(ODF2)	--	13.93134117	1210	11.04960398	1000	14.56945205	1240	11.5391872	1016	11.68257342	983	9.625285461	784	0.920165095	-0.282546764	normal	0.978193084	-0.046092929	normal	0.014066571	-0.668671202	normal	0.079597487	-0.331611395	normal	--	--	--	K16479|0|mcc:717505|ODF2; outer dense fiber of sperm tails 2; K16479 outer dense fiber protein 2 (A)	--	--	--	--	Outer dense fiber protein 2 GN=ODF2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: outer dense fiber protein 2 isoform X4 [Galeopterus variegatus]
ENSG00000136813(KIAA0368)	--	27.43015402	3652	33.00598742	3702	32.56929681	3817	33.80662326	3924	33.2138565	3922	28.459464	3665	0.990892162	0.072776473	normal	0.990943053	0.061833541	normal	0.990941654	-0.066890382	normal	0.943692233	0.021945007	normal	--	--	Molecular Function: protein complex scaffold (GO:0032947);; Biological Process: proteasome assembly (GO:0043248);; 	K11886|0|hsa:23392|ECM29; KIAA0368; K11886 proteasome component ECM29 (A)	--	[S]	Function unknown	Proteasome stabiliser;; HEAT repeat;; HEAT repeats;; HEAT-like repeat;; Vacuolar 14 Fab1-binding region	Proteasome-associated protein ECM29 homolog GN=ECM29 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: proteasome-associated protein ECM29 homolog [Eptesicus fuscus]
ENSG00000136816(TOR1B)	--	18.268934	870	15.71654646	759	17.28161509	829	16.493994	791	16.08440584	766	15.555998	735	0.963183681	-0.16785891	normal	0.975825294	-0.008165856	normal	0.959230311	-0.181567299	normal	0.608931201	-0.122224361	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	[R]	General function prediction only	Torsin;; ATPase family associated with various cellular activities (AAA)	Torsin-1B (Precursor) GN=TOR1B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: torsin-1B [Orycteropus afer afer]
ENSG00000136819(C9orf78)	--	20.96915	826	18.48358	736	23.0773	914	23.39193	923	24.03064	938	21.3237	839	0.9704996	0.129129312	normal	0.868277918	0.327857597	normal	0.970331519	-0.131587473	normal	0.670633868	0.103821151	normal	--	--	--	--	--	[S]	Function unknown	Hepatocellular carcinoma-associated antigen 59	Uncharacterized protein C9orf78 GN=C9orf78 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf78 homolog isoform 2 [Dasypus novemcinctus]
ENSG00000136824(SMC2)	--	25.50407805	3023	27.33551502	3218	28.95315473	3331	23.28569001	2781	20.88461304	2462	20.99196116	2512	0.984149652	-0.15112938	normal	0.781996532	-0.407540437	normal	0.749072771	-0.415192519	normal	0.042035004	-0.32512647	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: chromosome (GO:0005694);; Biological Process: chromosome organization (GO:0051276);; 	"K06674|0|hsa:10592|SMC2, CAP-E, CAPE, SMC-2, SMC2L1; structural maintenance of chromosomes 2; K06674 structural maintenance of chromosome 2 (A)"	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	RecF/RecN/SMC N terminal domain;; SMC proteins Flexible Hinge Domain;; AAA domain	Structural maintenance of chromosomes protein 2 GN=SMC2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: structural maintenance of chromosomes protein 2 [Galeopterus variegatus] 
ENSG00000136826(KLF4)	--	3.650644886	167	3.959161467	179	1.750569534	76	6.04778	267	3.919447395	168	4.123209391	183	0.193094718	0.64145367	normal	0.961430795	-0.11194842	normal	5.97E-05	1.243043371	up	0.360290855	0.52654352	normal	[R]	General function prediction only	--	K17846|0|ptr:464640|KLF4; Kruppel-like factor 4 (gut); K17846 krueppel-like factor 4 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain"	Krueppel-like factor 4 GN=KLF4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: Krueppel-like factor 4 isoform X2 [Camelus bactrianus]
ENSG00000136827(TOR1A)	--	33.5867	1240	31.9532	1184	33.1771	1222	34.9915	1295	36.4144	1336	29.3466	1082	0.981895786	0.031741229	normal	0.972232391	0.15264075	normal	0.965279881	-0.183593607	normal	0.989637954	0.00464397	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	[R]	General function prediction only	Torsin	Torsin-1A (Precursor) GN=TOR1A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: torsin-1A [Orycteropus afer afer]
ENSG00000136828(RALGPS1)	--	4.14404865	449	4.588335447	384	4.634451768	418	1.825208531	194	3.186124784	341	2.71910676	244	5.43E-08	-1.234864703	down	0.94735112	-0.191958329	normal	0.006859351	-0.781168795	normal	0.004070579	-0.703710014	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[T]	Signal transduction mechanisms	RasGEF domain;; PH domain	Ras-specific guanine nucleotide-releasing factor RalGPS1 GN=RALGPS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras-specific guanine nucleotide-releasing factor RalGPS1 isoform X2 [Camelus ferus]
ENSG00000136830(FAM129B)	--	75.2255	6397	73.5387	6403	77.1317	6741	100.4606	8559	95.6735	8068	93.0596	7931	0.895851558	0.389133458	normal	0.964105117	0.311970749	normal	0.985856737	0.226201883	normal	0.078022675	0.308352513	normal	--	--	--	--	--	--	--	--	Niban-like protein 1 GN=FAM129B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: niban-like protein 1 [Mustela putorius furo]
ENSG00000136834(OR1J1)	--	0.403963	4	0.404348	4	0.0995717	0	0.297238	3	0	0	0.395525	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:347168|OR1J1, OR9-18, hg32; olfactory receptor, family 1, subfamily J, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 1J1 GN=OR1J1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 1J1-like [Tupaia chinensis] 
ENSG00000136840(ST6GALNAC4)	--	19.42627746	630	12.9165093	413	17.86998002	552	10.4955788	335	12.37418633	364	10.31967574	316	4.36E-05	-0.938827552	normal	0.944511971	-0.202838109	normal	0.00173936	-0.810063287	normal	0.012993221	-0.673187885	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03374|0|hsa:27090|ST6GALNAC4, IV, SIAT3-C, SIAT3C, SIAT7-D, SIAT7D, ST6GALNACIV, ST6GalNAc; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 (EC:2.4.99.7); K03374 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7D) [EC:2.4.99.7] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase GN=ST6GALNAC4 OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase [Oryctolagus cuniculus]"
ENSG00000136842(TMOD1)	--	0.512056013	34	0.336804	23	0.468885192	30	0.70374886	48	0.997617898	68	0.7403608	50	0.958619543	0.449503047	normal	0.006953656	1.483230388	up	0.881601965	0.701031333	normal	0.079135252	0.911364865	normal	--	--	Molecular Function: tropomyosin binding (GO:0005523);; Biological Process: pointed-end actin filament capping (GO:0051694);; 	"K10370|0|hsa:7111|TMOD1, D9S57E, ETMOD, TMOD; tropomodulin 1; K10370 tropomodulin (A)"	--	[Z]	Cytoskeleton	Tropomodulin	Tropomodulin-1 GN=TMOD1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tropomodulin-1 [Elephantulus edwardii]
ENSG00000136848(DAB2IP)	--	7.287494514	988	6.941689612	953	7.696329891	905	7.527118006	1006	7.649990713	1024	7.064694891	888	0.97950549	-0.004777543	normal	0.976316378	0.082115317	normal	0.977865573	-0.035589518	normal	0.967635723	0.014412516	normal	--	--	Biological Process: regulation of GTPase activity (GO:0043087);; 	--	--	[R]	General function prediction only	Domain of unknown function (DUF3498);; GTPase-activator protein for Ras-like GTPase;; C2 domain	Disabled homolog 2-interacting protein GN=DAB2IP OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: disabled homolog 2-interacting protein isoform 1 [Odobenus rosmarus divergens]
ENSG00000136854(STXBP1)	--	25.33321359	1668	20.274675	1412	21.889348	1565	12.16405636	850	11.32500402	732	10.47033871	665	4.59E-07	-1.002097637	down	3.31E-06	-0.967784392	normal	5.36E-11	-1.241130741	down	9.87E-15	-1.069571295	down	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	"K15292|0|mmu:20910|Stxbp1, AI317162, AI326233, MMS10-G, Ms10g, Munc-18a, Munc18-1, N-sec1, Rb-sec1, Sxtbp1, Unc18-1, Unc18h, nsec1; syntaxin binding protein 1; K15292 syntaxin-binding protein 1 (A)"	Synaptic vesicle cycle (ko04721)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec1 family	Syntaxin-binding protein 1 GN=STXBP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-binding protein 1 isoform X1 [Bubalus bubalis]
ENSG00000136856(SLC2A8)	--	14.12721577	355	13.47201845	307	13.24221982	315	13.03910756	320	13.33045049	344	11.9661523	294	0.951045121	-0.179759437	normal	0.957381638	0.142081914	normal	0.962704608	-0.107293807	normal	0.902498766	-0.049765588	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08145|0|ptr:739414|SLC2A8; solute carrier family 2 (facilitated glucose transporter), member 8; K08145 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 8 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 8 GN=SLC2A8 OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 8 [Panthera tigris altaica]"
ENSG00000136859(ANGPTL2)	--	0	0	0.0214942	1	0	0	0	0	0.0417001	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-related protein 2 (Precursor) GN=ANGPTL2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: angiopoietin-related protein 2 [Galeopterus variegatus]
ENSG00000136861(CDK5RAP2)	--	12.07562387	1858	14.08352383	1968	13.039285	1929	11.92225841	1764	10.8399797	1594	12.16026363	1781	0.982545671	-0.105642531	normal	0.899972183	-0.325226876	normal	0.981438848	-0.123356392	normal	0.325309401	-0.184531493	normal	--	--	Cellular Component: microtubule organizing center (GO:0005815);; 	K16542|0|ptr:464695|CDK5RAP2; CDK5 regulatory subunit associated protein 2; K16542 CDK5 regulatory subunit-associated protein 2 (A)	--	--	--	Microtubule associated	CDK5 regulatory subunit-associated protein 2 GN=CDK5RAP2 OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: CDK5 regulatory subunit-associated protein 2 [Ceratotherium simum simum]
ENSG00000136866(ZFP37)	--	1.176578821	76	1.728130014	86	0.855957534	57	1.007764537	61	1.22474804	78	1.385589156	80	0.951111219	-0.340325279	normal	0.966435343	-0.159345439	normal	0.911139848	0.470170549	normal	0.986272296	-0.020955394	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7539|ZFP37, ZNF906, zfp-37; ZFP37 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; GATA zinc finger"	Zinc finger protein 37 homolog GN=ZFP37 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 37 homolog [Galeopterus variegatus]
ENSG00000136867(SLC31A2)	--	1.09704	32	0.474944	14	0.63844	18	0.549288	16	1.00329	29	0.748826	22	0.872718566	-0.964147888	normal	0.900273077	0.956127889	normal	0.98685416	0.261328499	normal	0.985893701	0.045705654	normal	--	--	Molecular Function: copper ion transmembrane transporter activity (GO:0005375);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: copper ion transmembrane transport (GO:0035434);; 	"K14687|3.41627e-88|pps:100994378|SLC31A2; solute carrier family 31 (copper transporter), member 2; K14687 solute carrier family 31 (copper transporter), member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Ctr copper transporter family	Probable low affinity copper uptake protein 2 GN=SLC31A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: probable low affinity copper uptake protein 2 [Galeopterus variegatus]
ENSG00000136868(SLC31A1)	--	17.2997	1399	17.152	1391	16.9183	1352	20.6788	1684	19.3851	1560	19.3119	1564	0.955012231	0.236426991	normal	0.975830636	0.143849316	normal	0.965163882	0.201644042	normal	0.299364901	0.193621575	normal	--	--	Molecular Function: copper ion transmembrane transporter activity (GO:0005375);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: copper ion transmembrane transport (GO:0035434);; 	"K14686|3.12523e-112|pon:100172583|SLC31A1; solute carrier family 31 (copper transporter), member 1; K14686 solute carrier family 31 (copper transporter), member 1 (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Ctr copper transporter family	High affinity copper uptake protein 1 GN=SLC31A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: high affinity copper uptake protein 1 [Camelus ferus] 
ENSG00000136869(TLR4)	--	0.669628148	63	0.812474157	75	1.09020204	97	1.221173101	114	1.537157369	138	1.842174782	162	0.261642947	0.809901438	normal	0.107673847	0.845530137	normal	0.22537058	0.722834002	normal	0.021469353	0.797455509	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K10160|0|ptr:743242|TLR4; toll-like receptor 4; K10160 toll-like receptor 4 (A)	NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Toll-like receptor signaling pathway (ko04620);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Malaria (ko05144);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Proteoglycans in cancer (ko05205);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323)	[T]	Signal transduction mechanisms	Leucine rich repeat;; TIR domain;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat;; TIR domain	Toll-like receptor 4 (Precursor) GN=TLR4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: toll-like receptor 4 isoform 1 [Ceratotherium simum simum]
ENSG00000136870(ZNF189)	--	5.595195561	379	5.13829047	361	6.163502778	404	5.445787036	382	5.65469797	384	6.515559995	445	0.969133703	-0.019379223	normal	0.966252037	0.067407106	normal	0.961806961	0.130692306	normal	0.867204305	0.061537159	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:472998|ZNF189; zinc finger protein 189; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 189 GN=ZNF189 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 189 isoformX1 [Equus caballus] 
ENSG00000136872(ALDOB)	--	0	0	0.04092118	1	0.023426554	0	0	0	0.022940328	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: fructose-bisphosphate aldolase activity (GO:0004332);; Biological Process: glycolytic process (GO:0006096);; 	"K01623|0|hsa:229|ALDOB, ALDB, ALDO2; aldolase B, fructose-bisphosphate (EC:4.1.2.13); K01623 fructose-bisphosphate aldolase, class I [EC:4.1.2.13] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Fructose-bisphosphate aldolase class-I	Fructose-bisphosphate aldolase B GN=ALDOB OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: fructose-bisphosphate aldolase B [Ursus maritimus]
ENSG00000136874(STX17)	--	9.717220018	828	9.567831437	857	10.71949049	904	10.43289185	1037	10.7265	960	11.68684132	1053	0.906141527	0.293393658	normal	0.968820297	0.142075674	normal	0.954431877	0.211491209	normal	0.26556388	0.21535667	normal	--	--	--	K08491|1.61404e-177|ptr:472994|STX17; syntaxin 17; K08491 syntaxin 17 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain	Syntaxin-17 GN=STX17 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-17 [Galeopterus variegatus]
ENSG00000136875(PRPF4)	--	26.1634	1444	27.1343	1486	28.0664	1540	29.2456	1614	30.0883	1626	25.4123	1386	0.978294049	0.129607094	normal	0.980159962	0.108361138	normal	0.973743702	-0.160128698	normal	0.921405102	0.027978852	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K12662|0|ptr:464671|PRPF4; pre-mRNA processing factor 4; K12662 U4/U6 small nuclear ribonucleoprotein PRP4 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"WD domain, G-beta repeat;; pre-mRNA processing factor 4 (PRP4) like"	U4/U6 small nuclear ribonucleoprotein Prp4 GN=PRPF4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U4/U6 small nuclear ribonucleoprotein Prp4 isoform X2 [Equus caballus] 
ENSG00000136877(FPGS)	--	25.57051004	986	21.07474895	822	25.11075521	990	29.599194	1106	29.96454691	1124	23.05561265	883	0.972327761	0.134661378	normal	0.638214947	0.429327235	normal	0.964131904	-0.173026497	normal	0.570471587	0.132332325	normal	[H]	Coenzyme transport and metabolism	--	"K01930|0|ggo:101143146|FPGS; folylpolyglutamate synthase, mitochondrial isoform 1; K01930 folylpolyglutamate synthase [EC:6.3.2.17] (A)"	Folate biosynthesis (ko00790)	[H]	Coenzyme transport and metabolism	Mur ligase middle domain	"Folylpolyglutamate synthase, mitochondrial (Precursor) GN=FPGS OS=Homo sapiens (Human) PE=1 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: folylpolyglutamate synthase, mitochondrial isoform X1 [Orycteropus afer afer]"
ENSG00000136878(USP20)	--	3.385322023	322	2.769294194	267	2.636445451	256	2.773270887	262	3.288190974	311	3.472540841	331	0.877383499	-0.32659489	normal	0.945587259	0.197610426	normal	0.840198081	0.360518138	normal	0.843912443	0.076706674	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11848|0|hsa:10868|USP20, LSFR3A, VDU2, hVDU2; ubiquitin specific peptidase 20 (EC:3.4.19.12); K11848 ubiquitin carboxyl-terminal hydrolase 20/33 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; DUSP domain;; Zn-finger in ubiquitin-hydrolases and other protein	Ubiquitin carboxyl-terminal hydrolase 20 GN=USP20 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 20 isoform 1 [Dasypus novemcinctus]
ENSG00000136881(BAAT)	--	9.859820481	471	9.940164907	472	9.596751848	446	14.39269218	711	14.75968589	721	15.02671076	740	0.169519687	0.561789271	normal	0.12197228	0.588250338	normal	0.00756278	0.720274325	normal	0.000255545	0.623813213	normal	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	"K00659|0|hsa:570|BAAT, BACAT, BAT; bile acid CoA:amino acid N-acyltransferase (EC:2.3.1.65 3.1.2.2); K00659 bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2] (A)"	Primary bile acid biosynthesis (ko00120);; Taurine and hypotaurine metabolism (ko00430);; Biosynthesis of unsaturated fatty acids (ko01040);; Peroxisome (ko04146);; Bile secretion (ko04976)	--	--	BAAT / Acyl-CoA thioester hydrolase C terminal;; Acyl-CoA thioester hydrolase/BAAT N-terminal region;; Dienelactone hydrolase family	Bile acid-CoA:amino acid N-acyltransferase GN=BAAT OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: bile acid-CoA:amino acid N-acyltransferase isoform X1 [Equus caballus] 
ENSG00000136883(KIF12)	--	0.961041034	36	0.185412788	6	1.143854533	25	0.841906326	32	1.719143516	57	1.612288782	24	0.981499341	-0.192057125	normal	2.30E-07	2.942423548	up	0.986746054	-0.063278113	normal	0.508742812	0.733241992	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10399|0|ggo:101136412|KIF12; kinesin-like protein KIF12; K10399 kinesin family member 12 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF12 GN=KIF12 OS=Homo sapiens (Human) PE=2 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF12 [Trichechus manatus latirostris]
ENSG00000136888(ATP6V1G1)	--	78.5239	1151	89.7055	1344	82.5268	1238	85.8735	1308	90.2211	1320	85.4242	1285	0.972012202	0.153450209	normal	0.981639932	-0.047367984	normal	0.981535301	0.045411152	normal	0.864771015	0.046663903	normal	--	--	--	"K02152|1.01217e-59|ptr:473030|ATP6V1G1; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1; K02152 V-type H+-transporting ATPase subunit G (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	Vacuolar (H+)-ATPase G subunit	V-type proton ATPase subunit G 1 GN=ATP6V1G1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit G 1 [Trichechus manatus latirostris]
ENSG00000136891(TEX10)	--	17.27236992	843	22.4250534	1038	21.4156257	1032	19.50383497	952	18.874283	913	17.8722439	871	0.968662886	0.144349014	normal	0.955879783	-0.206225608	normal	0.936025744	-0.252586377	normal	0.633300278	-0.111766131	normal	--	--	--	K14827|0|pps:100988922|TEX10; testis expressed 10; K14827 pre-rRNA-processing protein IPI1 (A)	--	[S]	Function unknown	Rix1 complex component involved in 60S ribosome maturation	Testis-expressed sequence 10 protein GN=TEX10 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: testis-expressed sequence 10 protein [Panthera tigris altaica]
ENSG00000136895(GARNL3)	--	1.818311001	118	2.6666864	103	2.068715903	104	1.606383068	68	2.047726664	88	1.18719927	33	0.219903298	-0.811902545	normal	0.953722964	-0.244605469	normal	2.93E-05	-1.620279355	down	0.037323733	-0.804718312	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	--	--	[T]	Signal transduction mechanisms	CNH domain;; Rap/ran-GAP	GTPase-activating Rap/Ran-GAP domain-like protein 3 GN=GARNL3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: GTPase-activating Rap/Ran-GAP domain-like protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000136908(DPM2)	--	58.575225	3337	58.911863	3711	56.94568	2952	60.762204	3725	66.208465	4254	68.815643	4644	0.987957149	0.127800765	normal	0.985030711	0.175518629	normal	0.023509721	0.645118116	normal	0.089093036	0.315215069	normal	--	--	Biological Process: dolichol metabolic process (GO:0019348);; Cellular Component: integral component of endoplasmic reticulum membrane (GO:0030176);; Molecular Function: enzyme regulator activity (GO:0030234);; 	"K09658|7.00637e-30|cjc:100388508|DPM2; dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit; K09658 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit (A)"	N-Glycan biosynthesis (ko00510);; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[O]	"Posttranslational modification, protein turnover, chaperones"	Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2)	Dolichol phosphate-mannose biosynthesis regulatory protein GN=DPM2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	"Dolichol phosphate-mannose biosynthesis regulatory protein, partial [Bos mutus]"
ENSG00000136925(TSTD2)	--	7.47088	587	6.99911	550	7.07274	551	8.27977	649	9.69965	758	8.98894	706	0.96785621	0.11374251	normal	0.606137444	0.440304424	normal	0.831242512	0.34847742	normal	0.125117241	0.303055564	normal	[R]	General function prediction only	--	--	--	--	--	Rhodanese-like domain	Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 GN=TSTD2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2 isoform X1 [Tupaia chinensis] 
ENSG00000136928(GABBR2)	--	0.025314658	3	0.016873973	2	0.0082735	0	0.027538334	3	0.04426146	4	0.058396479	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04615|0|mcf:102117646|GABBR2; gamma-aminobutyric acid (GABA) B receptor, 2; K04615 gamma-aminobutyric acid type B receptor (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; GABAergic synapse (ko04727);; Estrogen signaling pathway (ko04915);; Morphine addiction (ko05032)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	7 transmembrane sweet-taste receptor of 3 GCPR;; Receptor family ligand binding region;; Periplasmic binding protein	Gamma-aminobutyric acid type B receptor subunit 2 (Precursor) GN=GABBR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid type B receptor subunit 2 [Mustela putorius furo] 
ENSG00000136930(PSMB7)	--	149.16507	2149	149.18906	2172	144.35449	2082	153.00311	2268	152.77082	2179	133.78553	1958	0.987220767	0.04689026	normal	0.987235235	-0.016772805	normal	0.984354784	-0.096808222	normal	0.947441852	-0.021230427	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02739|0|hsa:5695|PSMB7, Z; proteasome (prosome, macropain) subunit, beta type, 7 (EC:3.4.25.1); K02739 20S proteasome subunit beta 2 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome beta subunits C terminal	Proteasome subunit beta type-7 (Precursor) GN=PSMB7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-7 [Galeopterus variegatus]
ENSG00000136931(NR5A1)	--	0.192707169	2	0.023660583	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08560|0|hsa:2516|NR5A1, AD4BP, ELP, FTZ1, FTZF1, POF7, SF-1, SF1, SPGF8, SRXY3; nuclear receptor subfamily 5, group A, member 1; K08560 steroidogenic factor 1 (A)"	--	[K]	Transcription	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Steroidogenic factor 1 GN=NR5A1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: steroidogenic factor 1 [Galeopterus variegatus]
ENSG00000136932(TRMO)	--	4.681212517	160	6.080991163	184	4.00567787	140	5.52442221	179	6.57039258	207	4.611771996	152	0.961260211	0.129875938	normal	0.956889012	0.147356128	normal	0.964154475	0.109220511	normal	0.771450822	0.130683521	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Uncharacterised protein family UPF0066	Nef-associated protein 1 GN=C9orf156 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nef-associated protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000136933(RABEPK)	--	19.27014172	530	18.94059442	520	22.422105	621	18.14948204	506	16.7185089	458	15.780575	449	0.967637362	-0.097398222	normal	0.945888855	-0.203958038	normal	0.483204158	-0.474803312	normal	0.231874146	-0.263213027	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Kelch motif"	Rab9 effector protein with kelch motifs GN=RABEPK OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rab9 effector protein with kelch motifs isoform 1 [Ceratotherium simum simum]
ENSG00000136935(GOLGA1)	--	9.707225376	1165	10.90235165	1284	11.00790453	1287	8.802367456	1042	9.338494758	1054	10.0634677	1193	0.962453001	-0.191539651	normal	0.903368265	-0.305798632	normal	0.976803155	-0.117565928	normal	0.275706157	-0.204568291	normal	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; 	"K16731|0|hsa:2800|GOLGA1, golgin-97; golgin A1; K16731 golgin subfamily A member 1 (A)"	--	--	--	GRIP domain	Golgin subfamily A member 1 GN=GOLGA1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: golgin subfamily A member 1 [Vicugna pacos]
ENSG00000136936(XPA)	--	8.62833	209	7.28949	169	6.81979	163	7.37645	174	8.580234	215	5.963571	146	0.91814129	-0.292884181	normal	0.899501266	0.323316479	normal	0.957846579	-0.16557104	normal	0.950946588	-0.037812009	normal	[L]	"Replication, recombination and repair"	--	"K10847|1.77858e-136|hsa:7507|XPA, XP1, XPAC; xeroderma pigmentosum, complementation group A; K10847 DNA-repair protein complementing XP-A cells (A)"	Nucleotide excision repair (ko03420)	[L]	"Replication, recombination and repair"	XPA protein C-terminus;; XPA protein N-terminal	DNA repair protein complementing XP-A cells GN=XPA OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein complementing XP-A cells isoform X1 [Pantholops hodgsonii]
ENSG00000136937(NCBP1)	--	22.202758	1879	20.94139763	1783	24.854921	2042	24.1108665	2049	21.67479441	1811	20.78386103	1740	0.984188287	0.094049	normal	0.985505258	0.0010524	normal	0.959036102	-0.23899504	normal	0.856384619	-0.048050668	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; Biological Process: RNA metabolic process (GO:0016070);; 	"K12882|0|ptr:464601|NCBP1; nuclear cap binding protein subunit 1, 80kDa; K12882 nuclear cap-binding protein subunit 1 (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040)	[A]	RNA processing and modification	MIF4G like;; MIF4G like;; MIF4G domain	Nuclear cap-binding protein subunit 1 GN=NCBP1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: nuclear cap-binding protein subunit 1 isoform X1 [Mustela putorius furo] 
ENSG00000136938(ANP32B)	--	151.701	5302	158.6632	5630	152.2495	5418	145.0038	5175	130.2516	4468	135.0668	4772	0.993083391	-0.065790772	normal	0.920259383	-0.354825039	normal	0.986140839	-0.191400825	normal	0.282685286	-0.203241423	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K18647|1.54135e-92|ggo:101153994|ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B; K18647 acidic leucine-rich nuclear phosphoprotein 32 family member B (A)	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine-rich repeat;; Leucine rich repeat	Acidic leucine-rich nuclear phosphoprotein 32 family member B GN=ANP32B OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: acidic leucine-rich nuclear phosphoprotein 32 family member B [Lipotes vexillifer]
ENSG00000136940(PDCL)	--	15.477924	684	18.3339665	812	16.52548265	699	16.698029	729	16.09455214	694	15.37648129	675	0.973910451	0.060957587	normal	0.934041643	-0.247471482	normal	0.973815596	-0.058567443	normal	0.747209522	-0.086789042	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Phosducin	Phosducin-like protein GN=PDCL OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: phosducin-like protein [Galeopterus variegatus]
ENSG00000136942(RPL35)	--	1848.59542	6981	1739.036379	6914	1840.13698	7477	2096.6145	8759	2012.7335	7602	1771.42734	7025	0.971520794	0.296441847	normal	0.993370099	0.115407784	normal	0.994011427	-0.098232248	normal	0.643260708	0.108175267	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02918|1.55886e-60|phd:102319720|60S ribosomal protein L35-like; K02918 large subunit ribosomal protein L35e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L29 protein	60S ribosomal protein L35 GN=RPL35 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	60S ribosomal protein L35 [Bos taurus] 
ENSG00000136943(CTSV)	--	13.8569	453	13.27114167	409	12.59864013	401	4.9890787	166	5.598282521	180	7.172711981	224	3.38E-11	-1.470559603	down	4.32E-07	-1.198656016	down	0.002118474	-0.844074843	normal	6.20E-09	-1.168217798	down	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K01375|0|hsa:1515|CTSV, CATL2, CTSL2, CTSU; cathepsin V (EC:3.4.22.43); K01375 cathepsin V [EC:3.4.22.43] (A)"	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin propeptide inhibitor domain (I29);; Peptidase C1-like family	Cathepsin L2 (Precursor) GN=CTSV OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin L1-like [Mustela putorius furo] 
ENSG00000136944(LMX1B)	--	1.681839233	132	1.071656986	83	1.299784954	101	0.633885911	71	0.611276385	76	0.975936844	99	0.055506499	-0.910783658	normal	0.967836516	-0.145761922	normal	0.970541573	-0.036592875	normal	0.399937717	-0.381475223	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09371|0|hsa:4010|LMX1B, LMX1.2, NPS1; LIM homeobox transcription factor 1, beta; K09371 LIM homeobox transcription factor 1 (A)"	--	[R]	General function prediction only	LIM domain;; Homeobox domain;; Homeobox KN domain	LIM homeobox transcription factor 1-beta GN=LMX1B OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LIM homeobox transcription factor 1-beta isoform X1 [Eptesicus fuscus]
ENSG00000136950(ARPC5L)	--	23.22983	613	23.20712	674	25.38882	708	30.82031	820	30.90999	789	21.40264	578	0.748783213	0.388061095	normal	0.950890779	0.205423795	normal	0.892892491	-0.300260205	normal	0.717518829	0.110581051	normal	--	--	Cellular Component: Arp2/3 protein complex (GO:0005885);; Cellular Component: actin cytoskeleton (GO:0015629);; Biological Process: regulation of actin filament polymerization (GO:0030833);; Biological Process: Arp2/3 complex-mediated actin nucleation (GO:0034314);; 	"K05754|6.9355e-100|ptr:739553|actin-related protein 2/3 complex subunit 5-like protein; K05754 actin related protein 2/3 complex, subunit 5 (A)"	Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	ARP2/3 complex 16 kDa subunit (p16-Arc)	Actin-related protein 2/3 complex subunit 5-like protein GN=ARPC5L OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	actin related protein 2/3 complex subunit 5-like protein [Sus scrofa] 
ENSG00000136960(ENPP2)	--	0.01661699	1	0	0	0	0	0	0	0.020345086	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: immune response (GO:0006955);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: polysaccharide binding (GO:0030247);; Molecular Function: metal ion binding (GO:0046872);; 	K01122|0|cfr:102509680|ENPP2; ectonucleotide pyrophosphatase/phosphodiesterase 2; K01122 ectonucleotide pyrophosphatase/phosphodiesterase family member 2 [EC:3.1.4.39] (A)	Ether lipid metabolism (ko00565)	[R]	General function prediction only	Type I phosphodiesterase / nucleotide pyrophosphatase;; Somatomedin B domain;; DNA/RNA non-specific endonuclease	Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Precursor) GN=ENPP2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform X6 [Felis catus]
ENSG00000136982(DSCC1)	--	10.1331	352	8.55484	299	10.3268	357	8.13465	288	8.11497	282	7.3526	256	0.881172812	-0.31879742	normal	0.961661149	-0.105328218	normal	0.551595135	-0.485630899	normal	0.239088943	-0.308602709	normal	--	--	Biological Process: mitotic sister chromatid cohesion (GO:0007064);; Cellular Component: Ctf18 RFC-like complex (GO:0031390);; 	"K11271|0|hsa:79075|DSCC1, DCC1; DNA replication and sister chromatid cohesion 1; K11271 sister chromatid cohesion protein DCC1 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Uncharacterized conserved protein (DUF2036)	Sister chromatid cohesion protein DCC1 GN=DSCC1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: sister chromatid cohesion protein DCC1 [Ceratotherium simum simum]
ENSG00000136986(DERL1)	--	39.23812758	1601	41.50900309	1414	41.33451872	1460	41.78880308	1538	43.48233414	1579	43.9622691	1731	0.982007076	-0.088663244	normal	0.976788666	0.137663117	normal	0.955707661	0.237120092	normal	0.679563542	0.094634561	normal	[S]	Function unknown	--	K11519|3.07591e-166|pps:100986783|DERL1; derlin 1; K11519 Derlin-1 (A)	Protein processing in endoplasmic reticulum (ko04141);; Amyotrophic lateral sclerosis (ALS) (ko05014)	[S]	Function unknown	Der1-like family	Derlin-1 GN=DERL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: derlin-1 [Loxodonta africana]
ENSG00000136997(MYC)	--	50.0059969	2075	55.62929841	2333	61.718429	2536	60.295079	2632	56.62239892	2495	46.017391	2109	0.922780707	0.312010364	normal	0.986839134	0.075379697	normal	0.94883563	-0.27410758	normal	0.889535588	0.037837217	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K04377|0|hsa:4609|MYC, MRTL, MYCC, bHLHe39, c-Myc; v-myc avian myelocytomatosis viral oncogene homolog; K04377 Myc proto-oncogene protein (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Cell cycle (ko04110);; PI3K-Akt signaling pathway (ko04151);; Wnt signaling pathway (ko04310);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; Thyroid hormone signaling pathway (ko04919);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Thyroid cancer (ko05216);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Central carbon metabolism in cancer (ko05230)	--	--	Myc amino-terminal region;; Myc leucine zipper domain;; Helix-loop-helix DNA-binding domain	Myc proto-oncogene protein GN=MYC OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myc proto-oncogene protein-like isoform X1 [Tupaia chinensis]
ENSG00000136999(NOV)	--	4.087633	188	6.695946	308	4.258464	195	4.526833	209	3.833250045	176	8.241327	381	0.961243214	0.120999889	normal	0.008596124	-0.82336073	normal	0.000246119	0.952643417	normal	0.900255264	0.128778248	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Insulin-like growth factor binding protein;; Cystine-knot domain;; von Willebrand factor type C domain;; Thrombospondin type 1 domain	Protein NOV homolog (Precursor) GN=NOV OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: protein NOV homolog [Galeopterus variegatus]
ENSG00000137033(IL33)	--	0.101283032	1	0.063041203	2	0.094640513	2	0.106293289	4	0.129544037	4	0.136225099	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; 	K12967|0|ptr:737537|IL33; interleukin 33; K12967 interleukin 33 (A)	Cytosolic DNA-sensing pathway (ko04623);; Influenza A (ko05164)	--	--	Interleukin 33	Interleukin-33 (109-270) (Precursor) GN=IL33 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: interleukin-33 isoform X2 [Physeter catodon]
ENSG00000137038(TMEM261)	--	13.74744	526	15.65579	599	14.59659	552	13.71879	531	12.20016	467	12.07353	465	0.972170497	-0.017133393	normal	0.780213482	-0.379471878	normal	0.924684191	-0.254966939	normal	0.347766377	-0.218643748	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4536)	Transmembrane protein 261 GN=TMEM261 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 261 [Felis catus] 
ENSG00000137040(RANBP6)	--	9.708075009	647	9.360960042	678	12.418337	795	16.80611656	1161	14.499221	992	12.91914207	896	0.00038995	0.811240988	normal	0.263331307	0.526651761	normal	0.964397186	0.163958487	normal	0.003836132	0.502598892	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	HEAT repeats;; HEAT repeat;; HEAT-like repeat;; Vacuolar 14 Fab1-binding region;; rRNA processing/ribosome biogenesis;; Armadillo/beta-catenin-like repeat	Ran-binding protein 6 GN=RANBP6 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	ran-binding protein 6 [Equus caballus]
ENSG00000137054(POLR1E)	--	20.053797	1325	18.86822367	1385	19.63083223	1344	22.3248036	1622	18.111103	1496	15.336426	1131	0.942586411	0.260675632	normal	0.980547838	0.089703385	normal	0.940123801	-0.256910109	normal	0.889273613	0.045551174	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K03005|0|ptr:747551|POLR1E; polymerase (RNA) I polypeptide E, 53kDa; K03005 DNA-directed RNA polymerase I subunit RPA49 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020)	[K]	Transcription	A49-like RNA polymerase I associated factor	DNA-directed RNA polymerase I subunit RPA49 GN=POLR1E OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase I subunit RPA49 [Ceratotherium simum simum]
ENSG00000137055(PLAA)	--	20.964307	1098	17.52902457	948	22.29315166	1028	21.80613235	1210	23.88234456	1196	21.978156	1119	0.976576205	0.109151204	normal	0.892697999	0.313385917	normal	0.975228179	0.113917663	normal	0.376138392	0.176137666	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14018|0|hsa:9373|PLAA, DOA1, PLA2P, PLAP; phospholipase A2-activating protein; K14018 phospholipase A-2-activating protein (A)"	Protein processing in endoplasmic reticulum (ko04141)	[I]	Lipid transport and metabolism	"PUL domain;; WD domain, G-beta repeat;; PFU (PLAA family ubiquitin binding)"	Phospholipase A-2-activating protein GN=PLAA OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: phospholipase A-2-activating protein [Oryctolagus cuniculus]
ENSG00000137070(IL11RA)	--	12.6113324	424	9.699999854	335	8.620888884	264	9.463963972	336	11.98494688	421	10.42991942	360	0.816856284	-0.364945814	normal	0.888146934	0.306994044	normal	0.689892672	0.437015567	normal	0.813963533	0.105381702	normal	--	--	--	"K05056|0|hsa:3590|IL11RA, CRSDA; interleukin 11 receptor, alpha; K05056 interleukin 11 receptor alpha (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640)	--	--	--	Interleukin-11 receptor subunit alpha (Precursor) GN=IL11RA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-11 receptor subunit alpha isoform X2 [Physeter catodon]
ENSG00000137073(UBAP2)	--	18.44905569	1476	19.60685252	1528	19.4609147	1612	18.320524	1451	18.3992147	1475	16.988345	1384	0.98281689	-0.05541928	normal	0.982018038	-0.072283327	normal	0.957640445	-0.22806809	normal	0.57654586	-0.120141654	normal	--	--	--	--	--	--	--	Ubiquitin-associated protein 2;; UBA/TS-N domain	Ubiquitin-associated protein 2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-associated protein 2 isoform X1 [Canis lupus familiaris]
ENSG00000137074(APTX)	--	17.80841353	618	16.92082701	590	17.7266388	634	22.04603472	766	21.09729251	732	22.62318996	798	0.912418291	0.278282914	normal	0.904214574	0.289035913	normal	0.86913528	0.322926451	normal	0.124567396	0.296857265	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10863|0|hsa:54840|APTX, AOA, AOA1, AXA1, EAOH, EOAHA, FHA-HIT; aprataxin; K10863 aprataxin [EC:3.-.-.-] (A)"	--	[R]	General function prediction only	Scavenger mRNA decapping enzyme C-term binding;; HIT domain;; FHA domain	Aprataxin GN=APTX OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	aprataxin [Sus scrofa] 
ENSG00000137075(RNF38)	--	5.55224363	406	5.679544516	414	4.690338736	341	7.204085174	527	6.65630674	492	7.36738298	546	0.840631752	0.344344515	normal	0.936917987	0.226840125	normal	0.035933796	0.668473909	normal	0.04567287	0.409355566	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF38 GN=RNF38 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 38-like isoform X2 [Tupaia chinensis]
ENSG00000137076(TLN1)	--	41.7275	8991	42.3587	9228	45.4828	9938	45.2051	9644	42.9897	9169	43.6379	9376	0.995611713	0.070306202	normal	0.995749639	-0.030675121	normal	0.995369798	-0.092259958	normal	0.955716397	-0.019498431	normal	--	--	Cellular Component: ruffle (GO:0001726);; Molecular Function: actin binding (GO:0003779);; Molecular Function: structural constituent of cytoskeleton (GO:0005200);; Cellular Component: focal adhesion (GO:0005925);; Biological Process: cytoskeletal anchoring at plasma membrane (GO:0007016);; Biological Process: protein metabolic process (GO:0019538);; 	"K06271|0|hsa:7094|TLN1, ILWEQ, TLN; talin 1; K06271 talin (A)"	Rap1 signaling pathway (ko04015);; Focal adhesion (ko04510);; Platelet activation (ko04611);; HTLV-I infection (ko05166)	[Z]	Cytoskeleton	"Talin, middle domain;; Vinculin Binding Site;; I/LWEQ domain;; FERM N-terminal domain;; FERM central domain;; PTB domain (IRS-1 type)"	Talin-1 GN=TLN1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: talin-1 [Camelus ferus]
ENSG00000137077(CCL21)	--	0	0	0	0	0	0	0	0	0.14792	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	K16062|9.10701e-68|ptr:746205|CCL21; chemokine (C-C motif) ligand 21; K16062 C-C motif chemokine 21 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	C-C motif chemokine 21 (Precursor) GN=CCL21 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: C-C motif chemokine 21 [Ursus maritimus]
ENSG00000137078(SIT1)	--	0	0	0	0	0	0	0.096679597	2	0.046877368	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"SHP2-interacting transmembrane adaptor protein, SIT"	Signaling threshold-regulating transmembrane adapter 1 (Precursor) GN=SIT1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: signaling threshold-regulating transmembrane adapter 1 [Galeopterus variegatus]
ENSG00000137094(DNAJB5)	--	2.876120274	134	3.285552822	124	2.733466134	134	3.752469	170	3.881094352	176	2.215784776	109	0.920729193	0.309314788	normal	0.758769217	0.478884069	normal	0.933579012	-0.302405329	normal	0.666230489	0.192803291	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09511|0|ptr:746375|DNAJB5; DnaJ (Hsp40) homolog, subfamily B, member 5; K09511 DnaJ homolog subfamily B member 5 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain	DnaJ homolog subfamily B member 5 GN=DNAJB5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 5 isoform 1 [Odobenus rosmarus divergens]
ENSG00000137098(SPAG8)	--	0.19634751	6	0.07332773	2	0.107423	2	0.188553	6	0.035680302	0	0.108630628	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sperm-associated antigen 8 GN=SPAG8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: sperm-associated antigen 8 [Physeter catodon]
ENSG00000137100(DCTN3)	--	57.8836215	646	58.41957582	674	59.43876753	686	82.11420175	945	74.68342376	823	68.06509844	768	0.280281829	0.516925976	normal	0.923120488	0.266176056	normal	0.964034515	0.15428469	normal	0.0845734	0.316449714	normal	--	--	--	K10425|2.52663e-131|pps:100975631|DCTN3; dynactin 3 (p22); K10425 dynactin 3 (A)	--	--	--	Dynactin subunit p22	Dynactin subunit 3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: dynactin subunit 3 [Galeopterus variegatus]
ENSG00000137101(CD72)	--	1.061396	42	1.25295	50	1.041	41	1.09149	43	0.923737	36	0.736645	29	0.981161321	0.003006379	normal	0.947555888	-0.47823352	normal	0.960661688	-0.486428031	normal	0.654852818	-0.323007942	normal	--	--	--	"K06504|0|hsa:971|CD72, CD72b, LYB2; CD72 molecule; K06504 CD72 antigen (A)"	B cell receptor signaling pathway (ko04662)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; UL45 protein	B-cell differentiation antigen CD72 GN=CD72 OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: B-cell differentiation antigen CD72 isoform X2 [Tupaia chinensis]
ENSG00000137103(TMEM8B)	--	5.552414448	248	3.783180051	174	4.1547405	199	3.322035641	150	4.165904601	181	4.508369508	207	0.050717014	-0.750166646	normal	0.965552048	0.035176078	normal	0.966132481	0.048211648	normal	0.531347473	-0.227222591	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3522)	Transmembrane protein 8B GN=TMEM8B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 8A-like isoform X3 [Mustela putorius furo] 
ENSG00000137106(GRHPR)	--	82.82731	1936	70.245322	1670	74.99831	1808	82.45714	1994	91.391829	2124	77.806074	1846	0.986676306	0.011745009	normal	0.902859081	0.325247395	normal	0.985914069	0.021698471	normal	0.578887906	0.118260283	normal	[CHR]	Energy production and conversion;; Coenzyme transport and metabolism;; General function prediction only	"Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00049|0|hsa:9380|GRHPR, GLXR, GLYD, PH2; glyoxylate reductase/hydroxypyruvate reductase (EC:1.1.1.79 1.1.1.81); K00049 glyoxylate/hydroxypyruvate reductase [EC:1.1.1.79 1.1.1.81] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Pyruvate metabolism (ko00620);; Glyoxylate and dicarboxylate metabolism (ko00630)"	[C]	Energy production and conversion	"D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain;; NAD binding domain of 6-phosphogluconate dehydrogenase;; NADP oxidoreductase coenzyme F420-dependent"	Glyoxylate reductase/hydroxypyruvate reductase GN=GRHPR OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: glyoxylate reductase/hydroxypyruvate reductase [Canis lupus familiaris]
ENSG00000137124(ALDH1B1)	--	29.64830904	1718	26.37600811	1549	31.61120725	1843	39.30990927	2288	37.58601025	2166	37.36651054	2169	0.80609133	0.382227685	normal	0.54322604	0.461886578	normal	0.964568338	0.226511035	normal	0.024050279	0.353039151	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00128|0|hsa:219|ALDH1B1, ALDH5, ALDHX; aldehyde dehydrogenase 1 family, member B1 (EC:1.2.1.3); K00128 aldehyde dehydrogenase (NAD+) [EC:1.2.1.3] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Glycerolipid metabolism (ko00561);; Pyruvate metabolism (ko00620)"	[C]	Energy production and conversion	Aldehyde dehydrogenase family	"Aldehyde dehydrogenase X, mitochondrial (Precursor) GN=ALDH1B1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: aldehyde dehydrogenase X, mitochondrial isoform X3 [Myotis brandtii] "
ENSG00000137133(HINT2)	--	58.7376	431	50.1754	388	51.8829	409	50.4481	391	50.1173	364	67.7957	513	0.954059881	-0.170712242	normal	0.962257917	-0.113089572	normal	0.874850921	0.317516141	normal	0.95619255	0.025857605	normal	[FGR]	Nucleotide transport and metabolism;; Carbohydrate transport and metabolism;; General function prediction only	--	--	--	[T]	Signal transduction mechanisms	HIT domain;; Scavenger mRNA decapping enzyme C-term binding	"Histidine triad nucleotide-binding protein 2, mitochondrial (Precursor) GN=HINT2 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: histidine triad nucleotide-binding protein 2, mitochondrial isoform X1 [Lipotes vexillifer]"
ENSG00000137135(ARHGEF39)	--	6.788436326	404	9.521997059	475	7.978308649	457	5.646453681	322	7.35535602	413	5.332114	350	0.831939762	-0.356603957	normal	0.938515313	-0.22245202	normal	0.764981946	-0.391645207	normal	0.162161165	-0.321030193	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	--	--	RhoGEF domain	Rho guanine nucleotide exchange factor 39 GN=ARHGEF39 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 39 [Myotis lucifugus]
ENSG00000137142(IGFBPL1)	--	2.601039078	149	3.020518	148	2.910795	154	5.545609126	320	6.723043	347	6.785084	355	5.04E-05	1.064268035	up	1.52E-06	1.199673745	up	1.23E-06	1.188689678	up	1.47E-07	1.159405926	up	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Kazal-type serine protease inhibitor domain;; Insulin-like growth factor binding protein;; Kazal-type serine protease inhibitor domain	Insulin-like growth factor-binding protein-like 1 (Precursor) GN=IGFBPL1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: insulin-like growth factor-binding protein-like 1 [Odobenus rosmarus divergens]
ENSG00000137145(DENND4C)	--	21.18377922	2613	28.57973939	3264	22.74399336	2681	17.943672	2115	15.70919924	1770	26.60762683	3169	0.898082117	-0.335661859	normal	1.26E-05	-0.903740315	normal	0.970509374	0.232844061	normal	0.490810223	-0.299041497	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; dDENN domain;; uDENN domain	DENN domain-containing protein 4C GN=DENND4C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 4C [Galeopterus variegatus]
ENSG00000137154(RPS6)	--	1477.286518	20420	1308.03742	17760	1360.810912	18175	1566.53535	22126	1569.35446	21671	1430.990653	19720	0.997698317	0.084921391	normal	0.990454435	0.265687079	normal	0.997152808	0.109404004	normal	0.531976893	0.151027458	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02991|2.70198e-150|tup:102489392|RPS6; ribosomal protein S6; K02991 small subunit ribosomal protein S6e (A)	Ribosome (ko03010);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Insulin signaling pathway (ko04910);; Proteoglycans in cancer (ko05205)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S6e	40S ribosomal protein S6 GN=RPS6 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S6 [Tursiops truncatus]
ENSG00000137161(CNPY3)	--	31.17825345	1031	34.22996946	1196	35.00197482	1184	23.868241	802	23.92391567	787	27.97737219	946	0.737991975	-0.392537173	normal	0.045399181	-0.624227798	normal	0.867220528	-0.331573595	normal	0.004489973	-0.448843681	normal	--	--	--	--	--	[S]	Function unknown	TLR4 regulator and MIR-interacting MSAP	Protein canopy homolog 3 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein canopy homolog 3 [Camelus bactrianus]
ENSG00000137166(FOXP4)	--	12.99981132	1156	12.97742216	1134	12.62173823	1129	13.21863846	1179	14.07373514	1266	12.51426823	1127	0.981317586	-0.002406776	normal	0.973651067	0.137256907	normal	0.980948248	-0.010834887	normal	0.882694946	0.041865803	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09409|0|hsa:116113|FOXP4, hFKHLA; forkhead box P4; K09409 forkhead box protein P (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein P4 GN=FOXP4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein P4 isoform X2 [Eptesicus fuscus]
ENSG00000137168(PPIL1)	--	25.3251	711	26.5216	741	28.2951	785	29.7816	844	28.35	794	25.3533	716	0.948305365	0.216132112	normal	0.973348591	0.078084941	normal	0.9668093	-0.140740499	normal	0.859655335	0.052008017	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	K12733|2.34112e-111|umr:103665441|PPIL1; peptidylprolyl isomerase (cyclophilin)-like 1; K12733 peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8] (A)	Spliceosome (ko03040)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase-like 1 GN=PPIL1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase-like 1 [Chrysochloris asiatica]
ENSG00000137171(KLC4)	--	4.638055499	201	4.998406384	200	3.516819522	208	4.451460371	226	4.808394624	229	5.096034457	243	0.959070907	0.137304861	normal	0.952352022	0.172699967	normal	0.943829236	0.214636231	normal	0.631716191	0.175878868	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10407|0|ptr:735843|KLC4; kinesin light chain 4; K10407 kinesin light chain (A)	Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Tetratricopeptide repeat;; Rabaptin-like protein;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Kinesin light chain 4 GN=KLC4 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin light chain 4 isoform X2 [Mustela putorius furo] 
ENSG00000137177(KIF13A)	--	13.43379078	1968	11.97201215	1719	14.05257075	1998	9.45145332	1419	8.637404036	1189	8.620725871	1261	0.328596161	-0.502223822	normal	0.167259897	-0.552659216	normal	0.010703294	-0.671634058	normal	5.62E-05	-0.57664337	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K17914|0|mcf:102116634|KIF13A; kinesin family member 13A; K17914 kinesin family member 13 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain;; Kinesin protein;; Kinesin protein 1B;; FHA domain	Kinesin-like protein KIF13A GN=KIF13A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin family member 13A isoform X1 [Equus caballus]
ENSG00000137185(ZSCAN9)	--	5.27316044	240	4.4670827	211	4.033276815	186	5.025749709	240	6.34654531	301	5.851381019	273	0.966696221	-0.030636138	normal	0.597883075	0.488150713	normal	0.461023213	0.54165042	normal	0.244560332	0.332699805	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:7746|ZSCAN9, PRD51, ZNF193; zinc finger and SCAN domain containing 9; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and SCAN domain-containing protein 9 GN=ZSCAN9 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 193 isoform 1 [Ceratotherium simum simum]
ENSG00000137193(PIM1)	--	11.9696	506	12.7596	546	13.1865	565	9.58067	406	7.78887	329	16.894	720	0.836583904	-0.347309793	normal	0.007945446	-0.749535379	normal	0.843585879	0.34064503	normal	0.802308514	-0.171634132	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K04702|0|mcf:102135814|PIM1; pim-1 oncogene; K04702 proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1] (A)	Jak-STAT signaling pathway (ko04630);; MicroRNAs in cancer (ko05206);; Acute myeloid leukemia (ko05221)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase pim-1 GN=PIM1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase pim-1, partial [Equus caballus]"
ENSG00000137198(GMPR)	--	0.377934	11	0.638664	19	0.0658572	1	0.16942	5	0.668655	19	0.405727	12	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00364|0|hsa:2766|GMPR, GMPR1; guanosine monophosphate reductase (EC:1.7.1.7); K00364 GMP reductase [EC:1.7.1.7] (A)"	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	IMP dehydrogenase / GMP reductase domain;; FMN-dependent dehydrogenase	GMP reductase 1 GN=GMPR OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: GMP reductase 1 [Ochotona princeps]
ENSG00000137200(CMTR1)	--	10.10282172	842	11.009232	914	10.87593878	914	11.22685355	934	11.69985633	943	12.0996773	1004	0.972028	0.118564582	normal	0.977993581	0.023598608	normal	0.972190839	0.127001198	normal	0.723064099	0.088809992	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: methylation (GO:0032259);; 	"K14589|0|pps:100973075|CMTR1, FTSJD2; cap methyltransferase 1; K14589 cap1 methyltransferase [EC:2.1.1.57] (A)"	--	[A]	RNA processing and modification	FtsJ-like methyltransferase;; G-patch domain	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 GN=CMTR1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1-like isoform X1 [Mustela putorius furo] 
ENSG00000137203(TFAP2A)	--	15.29720235	767	14.76359612	775	15.07410782	741	13.708594	732	15.65345863	835	12.8944499	682	0.971954528	-0.098014181	normal	0.973381091	0.085991652	normal	0.968001868	-0.127721453	normal	0.890037057	-0.04302334	normal	--	--	--	K09176|0|pon:100448058|TFAP2A; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); K09176 transcription factor AP-2 alpha/beta (A)	--	[K]	Transcription	Transcription factor AP-2	Transcription factor AP-2-alpha GN=TFAP2A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor AP-2-alpha-like isoform 1 [Odobenus rosmarus divergens] 
ENSG00000137207(YIPF3)	--	34.9724529	961	33.139629	910	32.7915789	914	36.65039123	986	39.80276002	1083	43.493741	1177	0.979221839	0.006209152	normal	0.948129131	0.229318544	normal	0.826711951	0.356036372	normal	0.307362686	0.200311153	normal	--	--	--	--	--	[S]	Function unknown	--	"Protein YIPF3, 36 kDa form III GN=YIPF3 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	PREDICTED: protein YIPF3 [Balaenoptera acutorostrata scammoni]
ENSG00000137210(TMEM14B)	--	108.8899734	1278	112.4593683	1322	109.0498404	1290	132.6001965	1593	100.908366	1175	111.214526	1318	0.924934801	0.286716926	normal	0.964668975	-0.191255746	normal	0.982424661	0.02266158	normal	0.857475623	0.048993939	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Putative binding domain;; Transmembrane proteins 14C	Transmembrane protein 14B GN=TMEM14B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 14C isoform X1 [Tupaia chinensis] 
ENSG00000137216(TMEM63B)	--	18.74732621	881	16.977591	758	20.71617069	899	18.33702268	857	17.72855192	830	21.2139311	976	0.97589977	-0.070554314	normal	0.971084344	0.109278535	normal	0.973797888	0.110090809	normal	0.868895966	0.04873557	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[R]	General function prediction only	"Domain of unknown function DUF221;; Late exocytosis, associated with Golgi transport;; Domain of unknown function (DUF4463)"	CSC1-like protein 2 GN=TMEM63B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 63B isoform X1 [Tupaia chinensis] 
ENSG00000137218(FRS3)	--	1.485053775	66	0.800990522	34	1.557829886	70	1.741958771	70	1.916968679	69	1.399229355	63	0.974946956	0.052861693	normal	0.346575163	0.968815815	normal	0.971525132	-0.156723766	normal	0.726530763	0.228087118	normal	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	--	--	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type)	Fibroblast growth factor receptor substrate 3 GN=FRS3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor receptor substrate 3 [Felis catus]
ENSG00000137221(TJAP1)	--	7.495370319	397	6.906588113	394	7.91346693	452	6.633336218	350	7.184908532	397	8.250066401	449	0.942177123	-0.211742832	normal	0.968761082	-0.010443249	normal	0.970697131	-0.017838886	normal	0.821676026	-0.075792444	normal	--	--	Cellular Component: tight junction (GO:0005923);; 	"K06105|0|hsa:93643|TJAP1, PILT, TJP4; tight junction associated protein 1 (peripheral); K06105 tight junction protein 4 (peripheral) (A)"	Tight junction (ko04530)	--	--	Protein incorporated later into Tight Junctions	Tight junction-associated protein 1 GN=TJAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: tight junction-associated protein 1 isoform X6 [Equus caballus] 
ENSG00000137225(CAPN11)	--	0	0	0	0	0	0	0.155720001	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K08580|0|hsa:11131|CAPN11, calpain11; calpain 11; K08580 calpain-11 [EC:3.4.22.-] (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III;; EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain"	Calpain-11 GN=CAPN11 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-11 [Oryctolagus cuniculus]
ENSG00000137251(TINAG)	--	0	0	0.03064409	1	0	0	0.0306265	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: proteolysis (GO:0006508);; Biological Process: immune response (GO:0006955);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; Molecular Function: polysaccharide binding (GO:0030247);; 	--	--	[R]	General function prediction only	Papain family cysteine protease;; Somatomedin B domain	Tubulointerstitial nephritis antigen GN=TINAG OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: tubulointerstitial nephritis antigen [Balaenoptera acutorostrata scammoni]
ENSG00000137261(KIAA0319)	--	2.240525849	277	3.334333509	407	2.529724359	326	2.735427686	334	2.248912708	297	4.175492636	528	0.932957787	0.237926701	normal	0.566772982	-0.473921778	normal	0.027827367	0.684854668	normal	0.787921283	0.178535703	normal	--	--	--	--	--	--	--	REJ domain;; Y_Y_Y domain;; PKD domain;; Domain of unknown function (DUF4625);; Putative Ig domain	Dyslexia-associated protein KIAA0319 (Precursor) GN=KIAA0319 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: dyslexia-associated protein KIAA0319 homolog isoform 1 [Equus caballus]
ENSG00000137265(IRF4)	--	0.0105454	1	0.0841458	8	0.0103993	0	0.0105333	1	0.0102208	0	0.0209008	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: regulatory region DNA binding (GO:0000975);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09445|0|ptr:462386|IRF4; interferon regulatory factor 4; K09445 interferon regulatory factor 4 (A)	--	--	--	Interferon-regulatory factor 3;; Interferon regulatory factor transcription factor	Interferon regulatory factor 4 GN=IRF4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: interferon regulatory factor 4 [Ceratotherium simum simum]
ENSG00000137266(SLC22A23)	--	8.016783457	702	6.679943356	576	7.392604782	654	7.073809384	559	7.166024648	651	7.6938162	700	0.812688289	-0.358573307	normal	0.960990252	0.154779751	normal	0.971544318	0.089572609	normal	0.9074175	-0.036930939	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08215|0|pps:100984712|SLC22A23; solute carrier family 22, member 23; K08215 MFS transporter, OCT family, solute carrier family 22 (organic anion transporter), member 23 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 23 GN=SLC22A23 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	"PREDICTED: solute carrier family 22 member 23, partial [Galeopterus variegatus]"
ENSG00000137267(TUBB2A)	--	8.94926	288	8.34218	275	7.81573	265	14.86651	489	10.76717	348	7.26966	243	0.013560375	0.729913128	normal	0.884136664	0.31667797	normal	0.959367096	-0.132537359	normal	0.493283727	0.359932595	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07375|0|rno:498736|Tubb2a; tubulin, beta 2A class IIa; K07375 tubulin beta (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta-2A chain GN=TUBB2A OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin beta-2A chain isoform 2 [Trichechus manatus latirostris]
ENSG00000137269(LRRC1)	--	3.68471366	190	4.418157	222	4.886378	216	4.269063004	237	4.796784	247	3.872393274	214	0.917867953	0.28598142	normal	0.958338478	0.13167416	normal	0.966815577	-0.021560302	normal	0.737108365	0.131075233	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine-rich repeat	Leucine-rich repeat-containing protein 1 GN=LRRC1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000137273(FOXF2)	--	13.1128	427	8.53423	282	9.39117	315	9.8421	323	12.2441	401	9.34307	308	0.673981295	-0.431741376	normal	0.540645218	0.484292396	normal	0.96737099	-0.040516201	normal	0.989067348	-0.01008478	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09399|3.33157e-161|ggo:101147343|FOXF2; forkhead box protein F2; K09399 forkhead box protein F (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein F2 GN=FOXF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: forkhead box protein F2 [Sus scrofa]
ENSG00000137274(BPHL)	--	11.60510527	350	9.66694011	309	12.83170005	370	13.32046804	374	13.39523135	387	11.72648383	337	0.967051249	0.064576835	normal	0.89373362	0.301977185	normal	0.958738681	-0.14245777	normal	0.841951529	0.072420839	normal	[R]	General function prediction only	--	"K18399|0|hsa:670|BPHL, BPH-RP, MCNAA, VACVASE; biphenyl hydrolase-like (serine hydrolase); K18399 valacyclovir hydrolase [EC:3.1.-.-] (A)"	--	[R]	General function prediction only	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Valacyclovir hydrolase (Precursor) GN=BPHL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: valacyclovir hydrolase isoform X1 [Felis catus]
ENSG00000137275(RIPK1)	--	6.0592695	554	5.919589	526	5.098727781	456	5.440167	479	6.578989884	582	5.630748	502	0.932363597	-0.239976032	normal	0.964639448	0.124190256	normal	0.963018058	0.129951208	normal	0.996330974	0.003895171	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; 	"K02861|0|hsa:8737|RIPK1, RIP, RIP1; receptor (TNFRSF)-interacting serine-threonine kinase 1 (EC:2.7.11.1); K02861 receptor-interacting serine/threonine-protein kinase 1 [EC:2.7.11.1] (A)"	NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; TNF signaling pathway (ko04668);; Hepatitis C (ko05160);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Death domain;; RIP homotypic interaction motif	Receptor-interacting serine/threonine-protein kinase 1 GN=RIPK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: receptor-interacting serine/threonine-protein kinase 1 [Vicugna pacos]
ENSG00000137285(TUBB2B)	--	2.64026	107	2.05894	85	2.62862	109	4.53151	185	4.94257	199	2.77506	113	0.124169634	0.750790725	normal	9.71E-05	1.191555185	up	0.969436674	0.043115663	normal	0.079245791	0.701397496	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07375|0|ssc:100153507|TUBB2B; tubulin, beta 2B class IIb; K07375 tubulin beta (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta-2B chain GN=TUBB2B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: tubulin beta-2B chain-like [Trichechus manatus latirostris]
ENSG00000137288(UQCC2)	--	32.3613	394	35.3083	399	36.4351	400	19.46895	258	24.36532	286	21.7803	290	0.098068841	-0.638554545	normal	0.487112117	-0.499552643	normal	0.574674563	-0.470141763	normal	0.013265344	-0.537273061	normal	--	--	--	"K17682|9.05727e-89|hsa:84300|UQCC2, C6orf125, Cbp6, M19, MNF1, bA6B20.2; ubiquinol-cytochrome c reductase complex assembly factor 2 (EC:2.7.4.21); K17682 mitochondrial nucleoid factor 1 (A)"	--	--	--	--	Ubiquinol-cytochrome-c reductase complex assembly factor 2 (Precursor) GN=UQCC2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ubiquinol-cytochrome-c reductase complex assembly factor 2 [Orycteropus afer afer]
ENSG00000137309(HMGA1)	--	378.438453	13083	321.48473	11108	370.833632	12993	376.239973	12908	329.63008	11343	252.96751	8845	0.996844045	-0.050254235	normal	0.996452175	0.008775433	normal	0.257461192	-0.563012044	normal	0.471362057	-0.190151345	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09282|6.67618e-11|rno:117062|Hmga1, Hmgi, Hmgiy; high mobility group AT-hook 1; K09282 high mobility group AT-hook protein 1 (A)"	--	--	--	AT hook motif	High mobility group protein HMG-I/HMG-Y GN=HMGA1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: high mobility group protein HMG-I/HMG-Y isoform X2 [Ochotona princeps]
ENSG00000137310(TCF19)	--	8.27167	517	7.96782	511	9.798757	635	7.61517	479	5.550578	349	6.64575	418	0.961625614	-0.140536827	normal	0.207420655	-0.569470295	normal	0.084729409	-0.609741943	normal	0.033420543	-0.437843816	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	FHA domain;; PHD-finger	Transcription factor 19 GN=TCF19 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor 19 [Equus caballus] 
ENSG00000137312(FLOT1)	--	44.14374829	1619	40.06239317	1570	45.17015134	1727	32.7201714	1291	34.1151251	1333	37.49194096	1441	0.838595002	-0.357065821	normal	0.944723933	-0.257245071	normal	0.940050493	-0.26923072	normal	0.074379104	-0.294937051	normal	[S]	Function unknown	--	K07192|0|hsa:10211|FLOT1; flotillin 1; K07192 flotillin (A)	Insulin signaling pathway (ko04910)	[UZ]	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	SPFH domain / Band 7 family	Flotillin-1 GN=FLOT1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: flotillin-1 [Leptonychotes weddellii]
ENSG00000137331(IER3)	--	184.06003	3447	147.27442	2789	135.8934	2594	120.48486	2297	121.46523	2282	101.94996	1934	0.043054634	-0.616083756	normal	0.929176021	-0.310689103	normal	0.665336796	-0.431589638	normal	0.024886356	-0.461020241	normal	--	--	--	--	--	--	--	--	Radiation-inducible immediate-early gene IEX-1 GN=IER3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: radiation-inducible immediate-early gene IEX-1 [Mustela putorius furo] 
ENSG00000137337(MDC1)	--	6.685060266	1205	6.693485922	1176	9.259971815	1423	7.1459515	943	5.907687	926	9.22402123	1075	0.765105954	-0.38398067	normal	0.81390914	-0.365699146	normal	0.689691781	-0.412384496	normal	0.014384153	-0.390222303	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	FHA domain;; BRCA1 C Terminus (BRCT) domain	Mediator of DNA damage checkpoint protein 1 GN=MDC1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: mediator of DNA damage checkpoint protein 1 [Lipotes vexillifer]
ENSG00000137338(PGBD1)	--	6.134273414	318	5.19390208	320	5.77282788	331	4.853646376	302	5.121351973	322	5.010309678	283	0.962940377	-0.104790838	normal	0.967188232	-0.012379454	normal	0.934978387	-0.233167244	normal	0.732504687	-0.116656962	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	Transposase IS4;; SCAN domain	PiggyBac transposable element-derived protein 1 GN=PGBD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: piggyBac transposable element-derived protein 1-like [Galeopterus variegatus]
ENSG00000137343(ATAT1)	--	4.15651138	176	5.2773638	199	5.294006553	211	3.714019946	147	5.11476704	185	4.007301225	168	0.926987048	-0.287837596	normal	0.959599208	-0.125678862	normal	0.894259702	-0.334381359	normal	0.49621365	-0.249499495	normal	--	--	Cellular Component: microtubule (GO:0005874);; Molecular Function: tubulin N-acetyltransferase activity (GO:0019799);; Biological Process: alpha-tubulin acetylation (GO:0071929);; 	--	--	[S]	Function unknown	Touch receptor neuron protein Mec-17	Alpha-tubulin N-acetyltransferase 1 {ECO:0000255|HAMAP-Rule:MF_03130} GN=Nbla00487 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: alpha-tubulin N-acetyltransferase isoformX2 [Equus caballus]
ENSG00000137364(TPMT)	--	8.522245154	330	6.214079	286	11.244577	427	8.954961	325	6.513414	272	5.4528538	251	0.967062401	-0.052611733	normal	0.962650687	-0.09332894	normal	0.00790932	-0.771234962	normal	0.321650542	-0.319976624	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: S-adenosylmethionine-dependent methyltransferase activity (GO:0008757);; 	K00569|0|hsa:7172|TPMT; thiopurine S-methyltransferase (EC:2.1.1.67); K00569 thiopurine S-methyltransferase [EC:2.1.1.67] (A)	Drug metabolism - other enzymes (ko00983)	--	--	Thiopurine S-methyltransferase (TPMT)	Thiopurine S-methyltransferase GN=TPMT OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: thiopurine S-methyltransferase [Camelus ferus] 
ENSG00000137393(RNF144B)	--	0.18450206	15	0.243783794	20	0.122023738	9	0.557164	45	0.309709202	24	0.526082179	43	0.116050501	1.463819583	normal	0.98548233	0.225992947	normal	0.003048055	2.074572812	up	0.021989069	1.325200069	normal	--	--	--	"K11975|0|ptr:462463|RNF144B, IBRDC2; ring finger protein 144B; K11975 E3 ubiquitin-protein ligase RNF144 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain	E3 ubiquitin-protein ligase RNF144B GN=RNF144B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	E3 ubiquitin-protein ligase RNF144B [Pteropus alecto]
ENSG00000137404(NRM)	--	13.41611107	299	12.96995855	280	14.89598715	324	18.6123591	413	16.82766299	371	17.49428797	383	0.678566581	0.433262634	normal	0.801045224	0.382764602	normal	0.934862167	0.232061821	normal	0.147600819	0.348770271	normal	--	--	--	--	--	--	--	NnrU protein	Nurim GN=NRM OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nurim isoform X1 [Galeopterus variegatus]
ENSG00000137409(MTCH1)	--	75.62020455	2699	73.58887664	2715	74.47772576	2741	83.49777585	3006	82.68385549	2950	77.83630586	2809	0.986133092	0.124520582	normal	0.987324249	0.09828367	normal	0.989488143	0.027048113	normal	0.722470756	0.082706994	normal	--	--	--	K17885|0|ptr:748005|MTCH1; mitochondrial carrier 1; K17885 mitochondrial carrier (A)	--	[R]	General function prediction only	Mitochondrial carrier protein	Mitochondrial carrier homolog 1 GN=MTCH1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial carrier homolog 1 isoform X2 [Sus scrofa]
ENSG00000137411(VARS2)	--	9.631861006	564	8.24964449	537	11.964024	536	7.762280674	437	8.846931003	502	8.322835602	527	0.735536933	-0.397659601	normal	0.964677819	-0.118316574	normal	0.971999249	-0.032628637	normal	0.466930052	-0.179807954	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01873|0|pps:100980341|VARS2; valyl-tRNA synthetase 2, mitochondrial; K01873 valyl-tRNA synthetase [EC:6.1.1.9] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (I, L, M and V);; Anticodon-binding domain of tRNA;; tRNA synthetases class I (M)"	"Valine--tRNA ligase, mitochondrial (Precursor) GN=VARS2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: valine--tRNA ligase, mitochondrial isoform X1 [Equus caballus]"
ENSG00000137413(TAF8)	--	7.615731684	378	6.448181936	383	5.499089199	355	3.852097304	304	4.588233176	324	6.455187698	386	0.85225034	-0.343586253	normal	0.920132205	-0.261652348	normal	0.96322279	0.112032578	normal	0.592767319	-0.15887925	normal	--	--	--	"K14649|9.67486e-175|pps:100971225|TAF8; TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa; K14649 transcription initiation factor TFIID subunit 8 (A)"	Basal transcription factors (ko03022)	[K]	Transcription	Bromodomain associated;; Transcription factor TFIID complex subunit 8 C-term;; Putative binding domain	Transcription initiation factor TFIID subunit 8 GN=TAF8 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 8 isoform X3 [Oryctolagus cuniculus]
ENSG00000137414(FAM8A1)	--	5.62007	374	5.899161	392	5.59452	367	5.714349	383	6.691956	448	5.709407	382	0.96925236	0.003459814	normal	0.953535344	0.170602522	normal	0.968197617	0.049301995	normal	0.822849126	0.077234368	normal	--	--	--	--	--	[S]	Function unknown	RDD family	Protein FAM8A1 GN=FAM8A1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM8A1 [Ceratotherium simum simum]
ENSG00000137434(C6orf52)	--	4.0288128	21	2.718935103	16	5.102140872	28	0.926257014	6	2.669064018	15	4.170697752	24	0.714710548	-1.606940957	normal	--	--	--	0.984286991	-0.217956745	normal	0.530575809	-0.547203953	normal	--	--	--	--	--	--	--	--	Putative uncharacterized protein C6orf52 GN=C6orf52 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized protein C6orf52 homolog [Ceratotherium simum simum]
ENSG00000137440(FGFBP1)	--	0.46633	13	0.644863	18	0.567001	15	0.936479	26	1.22221	34	1.03575	29	0.941175488	0.893324146	normal	0.90321693	0.843795422	normal	0.925366393	0.878144059	normal	0.160416574	0.931278085	normal	--	--	--	--	--	--	--	FGF binding protein 1 (FGF-BP1)	Fibroblast growth factor-binding protein 1 (Precursor) GN=FGFBP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor-binding protein 1-like [Galeopterus variegatus]
ENSG00000137449(CPEB2)	--	9.856779927	863	10.52591523	944	7.083486193	620	10.66277118	910	11.20799002	915	10.23956547	899	0.977324529	0.045594671	normal	0.976502467	-0.06633373	normal	0.250300017	0.526688655	normal	0.62496329	0.144688758	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K02602|0|mcf:102131520|CPEB2; cytoplasmic polyadenylation element binding protein 2; K02602 cytoplasmic polyadenylation element-binding protein (A)	Oocyte meiosis (ko04114);; Dorso-ventral axis formation (ko04320);; Progesterone-mediated oocyte maturation (ko04914)	[J]	"Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Cytoplasmic polyadenylation element-binding protein 2 GN=CPEB2 OS=Homo sapiens (Human) PE=2 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: cytoplasmic polyadenylation element-binding protein 2 isoform X4 [Monodelphis domestica]
ENSG00000137460(FHDC1)	--	0.21962517	30	0.208937289	28	0.139463108	18	0.551865269	75	0.499283281	69	0.415317986	56	0.032173997	1.249354339	normal	0.055353729	1.235911121	normal	0.015246788	1.551626159	normal	0.002871362	1.373138867	up	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain	FH2 domain-containing protein 1 GN=FHDC1 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: FH2 domain-containing protein 1 [Galeopterus variegatus]
ENSG00000137462(TLR2)	--	1.24E-07	0	4.41E-07	0	0.126153	8	0.0904968	6	1.92E-07	0	0.0419112	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K10159|0|hsa:7097|TLR2, CD282, TIL4; toll-like receptor 2; K10159 toll-like receptor 2 (A)"	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Toll-like receptor signaling pathway (ko04620);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Malaria (ko05144);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Measles (ko05162);; Herpes simplex infection (ko05168);; Proteoglycans in cancer (ko05205);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323)	[T]	Signal transduction mechanisms	TIR domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; TIR domain;; Leucine rich repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeat	Toll-like receptor 2 (Precursor) GN=TLR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	RecName: Full=Toll-like receptor 2; AltName: CD_antigen=CD282; Flags: Precursor [Canis lupus familiaris] 
ENSG00000137463(MGARP)	--	1.97352	49	0.876639	22	1.4157	35	0.918181	23	1.40347	35	1.03432	26	0.487011275	-1.07179539	normal	0.952428911	0.61467341	normal	0.97308518	-0.416197805	normal	0.643745166	-0.356138611	normal	--	--	--	--	--	--	--	Mitochondria Localisation Sequence	Protein MGARP GN=MGARP OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein MGARP [Ceratotherium simum simum]
ENSG00000137474(MYO7A)	--	1.9653	131	1.467106862	100	1.994747603	135	1.018681752	67	1.174684207	78	1.412438547	96	0.024313361	-0.981753498	normal	0.924215691	-0.373467833	normal	0.801480346	-0.493556102	normal	0.099887596	-0.622574711	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoskeleton (GO:0005856);; Cellular Component: myosin complex (GO:0016459);; 	"K10359|0|hsa:4647|MYO7A, DFNA11, DFNB2, MYOVIIA, MYU7A, NSRD2, USH1B; myosin VIIA; K10359 myosin VII (A)"	--	[N]	Cell motility	Myosin head (motor domain);; MyTH4 domain;; FERM central domain;; IQ calmodulin-binding motif;; FERM N-terminal domain;; Ras association (RalGDS/AF-6) domain	Unconventional myosin-VIIa GN=MYO7A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-VIIa isoform X1 [Canis lupus familiaris]
ENSG00000137478(FCHSD2)	--	5.925348845	458	7.421031705	500	8.105435646	556	7.903079122	603	7.346976169	588	7.976127876	635	0.803953553	0.364908466	normal	0.944379879	0.211870064	normal	0.954944916	0.182914415	normal	0.251200243	0.249527884	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	"SH3 domain;; Variant SH3 domain;; Fes/CIP4, and EFC/F-BAR homology domain;; Variant SH3 domain"	FCH and double SH3 domains protein 2 GN=FCHSD2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: FCH and double SH3 domains protein 2 isoform X2 [Tupaia chinensis]
ENSG00000137486(ARRB1)	--	4.584312751	383	1.888684421	193	3.232265138	316	1.649994129	187	3.306042678	306	1.928266244	247	1.73E-05	-1.058921815	down	0.163408874	0.639492177	normal	0.841416662	-0.361741705	normal	0.643959313	-0.289477811	normal	--	--	--	"K04439|0|ptr:451424|ARRB1; arrestin, beta 1; K04439 beta-arrestin (A)"	MAPK signaling pathway (ko04010);; Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Phototransduction (ko04744);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	"Arrestin (or S-antigen), N-terminal domain;; Arrestin (or S-antigen), C-terminal domain"	Beta-arrestin-1 GN=ARRB1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: beta-arrestin-1 [Loxodonta africana]
ENSG00000137491(SLCO2B1)	--	0.885335054	32	0.528193285	28	0.523799474	15	0.256663332	20	0.429438594	25	0.376824723	20	0.953568693	-0.667975255	normal	0.983928366	-0.174921111	normal	0.986502376	0.374000628	normal	0.823164267	-0.228560407	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14352|0|pps:100983626|SLCO2B1; solute carrier organic anion transporter family, member 2B1; K14352 solute carrier organic anion transporter family, member 2B (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily	Solute carrier organic anion transporter family member 2B1 GN=SLCO2B1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 2B1 [Physeter catodon]
ENSG00000137492(THAP12)	--	22.339531	1411	22.134735	1382	21.746669	1347	25.335043	1593	23.77412	1488	23.368692	1469	0.976349813	0.144048336	normal	0.980787298	0.085100597	normal	0.978563364	0.116667643	normal	0.59683371	0.114727479	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	--	--	THAP domain;; Domain of unknown function (DUF4371);; hAT family C-terminal dimerisation region	52 kDa repressor of the inhibitor of the protein kinase GN=PRKRIR OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: 52 kDa repressor of the inhibitor of the protein kinase [Camelus dromedarius]
ENSG00000137494(ANKRD42)	--	4.379598613	252	5.844970194	311	4.909663742	269	7.365366155	412	7.392295667	389	7.0398432	375	0.052984487	0.675139694	normal	0.895101818	0.300121798	normal	0.594192323	0.468751205	normal	0.033100633	0.477628603	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17593|0|hsa:338699|ANKRD42, PPP1R79, SARP; ankyrin repeat domain 42; K17593 ankyrin repeat domain-containing protein 42 (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 42 GN=ANKRD42 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 42 isoform 1 [Ceratotherium simum simum]
ENSG00000137496(IL18BP)	--	3.0153598	178	3.41478	176	2.786477	155	3.87656	212	4.230335	262	4.8541127	246	0.94445265	0.219616128	normal	0.46391127	0.548677531	normal	0.193483568	0.652998165	normal	0.090259711	0.479418335	normal	--	--	--	--	--	--	--	--	Interleukin-18-binding protein (Precursor) GN=IL18BP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: interleukin-18-binding protein isoform X7 [Galeopterus variegatus]
ENSG00000137497(NUMA1)	--	31.73671231	4715	28.8826708	4776	29.55358732	4664	33.70217186	4098	36.3433656	4291	43.45672619	4580	0.977877825	-0.233088492	normal	0.986389825	-0.175856712	normal	0.992813896	-0.034500343	normal	0.476322227	-0.147127585	normal	--	--	--	K16808|0|ptr:451398|NUMA1; nuclear mitotic apparatus protein 1; K16808 nuclear mitotic apparatus protein 1 (A)	--	--	--	--	Nuclear mitotic apparatus protein 1 {ECO:0000312|HGNC:HGNC:8059} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nuclear mitotic apparatus protein 1 isoform X1 [Galeopterus variegatus] 
ENSG00000137500(CCDC90B)	--	28.2755426	771	28.6525232	786	29.67013468	909	28.21329858	797	23.47204977	741	30.31678419	844	0.976589989	0.016983314	normal	0.970885704	-0.106271699	normal	0.972361598	-0.115129907	normal	0.792791575	-0.070772611	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1640)	"Coiled-coil domain-containing protein 90B, mitochondrial (Precursor) GN=CCDC90B OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: coiled-coil domain-containing protein 90B, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000137501(SYTL2)	--	7.196105958	428	7.270490392	399	8.817155892	436	20.99039969	1330	20.39394484	1382	13.51911578	882	0	1.601480055	up	0	1.767042645	up	2.21E-06	1.005656646	up	3.92E-06	1.486632968	up	--	--	--	K17598|0|mcf:102115536|SYTL2; synaptotagmin-like 2; K17598 synaptotagmin-like protein (A)	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; FYVE-type zinc finger	Synaptotagmin-like protein 2 GN=SYTL2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-like protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000137502(RAB30)	--	3.036463428	184	3.517483254	181	2.779712688	188	3.935171821	304	3.189076105	274	2.815394955	222	0.080097302	0.68901469	normal	0.373784749	0.572844076	normal	0.940811182	0.229832442	normal	0.052475015	0.510673427	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07917|1.14567e-148|umr:103675326|RAB30; RAB30, member RAS oncogene family; K07917 Ras-related protein Rab-30 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase;; Conserved hypothetical ATP binding protein	Ras-related protein Rab-30 (Precursor) GN=RAB30 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-30 isoform X1 [Monodelphis domestica]
ENSG00000137504(CREBZF)	--	35.10378289	2279	37.12099853	2431	40.02181079	2373	29.173933	2010	36.29646755	2375	36.873849	2482	0.969918934	-0.211885449	normal	0.987461991	-0.055014312	normal	0.98782578	0.056464386	normal	0.788556097	-0.065207057	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	bZIP transcription factor	CREB/ATF bZIP transcription factor GN=CREBZF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CREB/ATF bZIP transcription factor [Orcinus orca] 
ENSG00000137507(LRRC32)	--	0.060610256	4	0.084720384	7	0	0	0.082931017	2	0.038422884	2	0.024172546	2	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat N-terminal domain	Leucine-rich repeat-containing protein 32 (Precursor) GN=LRRC32 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 32 [Galeopterus variegatus]
ENSG00000137509(PRCP)	--	38.4621335	1413	33.96004	1339	31.6951961	1200	32.1987939	1192	35.6925356	1287	31.80198051	1144	0.9297111	-0.275882395	normal	0.980111706	-0.078480047	normal	0.979267388	-0.077139219	normal	0.480401223	-0.146882405	normal	--	--	--	"K01285|8.52123e-36|hsa:5547|PRCP, HUMPCP, PCP; prolylcarboxypeptidase (angiotensinase C) (EC:3.4.16.2); K01285 lysosomal Pro-X carboxypeptidase [EC:3.4.16.2] (A)"	Protein digestion and absorption (ko04974)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Putative binding domain	Endonuclease OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"hypothetical protein M91_14419, partial [Bos mutus]"
ENSG00000137513(NARS2)	--	13.4979577	488	15.20499433	547	11.74554056	482	12.3047275	492	13.38803805	534	15.0512769	562	0.97137438	-0.018995534	normal	0.970491884	-0.055971028	normal	0.944217869	0.212627165	normal	0.895946735	0.04506573	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01893|0|ggo:101145500|NARS2; probable asparagine--tRNA ligase, mitochondrial isoform 1; K01893 asparaginyl-tRNA synthetase [EC:6.1.1.22] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class II (D, K and N);; OB-fold nucleic acid binding domain;; tRNA synthetases class II core domain (F)"	"Probable asparagine--tRNA ligase, mitochondrial (Precursor) GN=NARS2 OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable asparagine--tRNA ligase, mitochondrial isoform X1 [Equus caballus] "
ENSG00000137522(RNF121)	--	15.21808761	656	17.32406559	780	15.8649679	694	26.57069339	1094	25.71388235	1099	23.59544197	1023	0.0065269	0.705720062	normal	0.471461986	0.472443685	normal	0.168724577	0.55051307	normal	0.000210682	0.57294868	normal	--	--	--	K15698|0|pps:100996086|RNF121; ring finger protein 121; K15698 RING finger protein 121 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ring finger domain	RING finger protein 121 GN=RNF121 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 121 isoform X1 [Camelus ferus]
ENSG00000137547(MRPL15)	--	40.07811773	724	46.99038042	860	41.04600034	739	52.82418478	976	44.26096272	801	49.68146931	906	0.7186043	0.399327	normal	0.970056577	-0.123735455	normal	0.910688736	0.285117435	normal	0.370083057	0.186196882	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02876|0|ptr:472764|MRPL15; mitochondrial ribosomal protein L15; K02876 large subunit ribosomal protein L15 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L18e/L15	"39S ribosomal protein L15, mitochondrial (Precursor) GN=MRPL15 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L15, mitochondrial [Ailuropoda melanoleuca] "
ENSG00000137561(TTPA)	--	1.1944528	56	1.325034616	67	1.550950908	75	0.815171	32	0.797752623	41	0.785803111	30	0.754747497	-0.808460141	normal	0.772724311	-0.709291851	normal	0.020073991	-1.2877875	normal	0.041966434	-0.963742579	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	"CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain"	Alpha-tocopherol transfer protein GN=TTPA OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: alpha-tocopherol transfer protein [Oryctolagus cuniculus]
ENSG00000137563(GGH)	--	82.3086	1924	81.0279	1926	75.9625	1796	58.4748	1382	55.5422	1296	63.7213	1496	0.304384528	-0.507702615	normal	0.079721783	-0.592397521	normal	0.939726431	-0.271717559	normal	0.002117368	-0.456906792	normal	--	--	Biological Process: glutamine metabolic process (GO:0006541);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01307|0|ptr:464204|GGH; gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase); K01307 gamma-glutamyl hydrolase [EC:3.4.19.9] (A)"	Folate biosynthesis (ko00790)	[H]	Coenzyme transport and metabolism	Peptidase C26;; Glutamine amidotransferase class-I	Gamma-glutamyl hydrolase (Precursor) GN=GGH OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: gamma-glutamyl hydrolase [Oryctolagus cuniculus]
ENSG00000137571(SLCO5A1)	--	0.173396813	14	0.021199494	3	0.02119101	2	0.349703153	29	0.661252881	69	0.411163346	35	0.911096512	0.946342602	normal	4.42E-12	3.948341137	up	2.93E-05	3.371565185	up	0.00646247	2.785527602	up	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14356|0|pps:100978893|SLCO5A1; solute carrier organic anion transporter family, member 5A1; K14356 solute carrier organic anion transporter family, member 5A (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Solute carrier organic anion transporter family member 5A1 GN=SLCO5A1 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 5A1 isoform X1 [Ursus maritimus]
ENSG00000137573(SULF1)	--	0	0	0	0	0	0	0	0	0	0	0.134268025	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K14607|0|hsa:23213|SULF1, HSULF-1, SULF-1; sulfatase 1; K14607 extracellular sulfatase Sulf [EC:3.1.6.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Sulfatase;; Sulfatase protein;; Type I phosphodiesterase / nucleotide pyrophosphatase	Extracellular sulfatase Sulf-1 (Precursor) GN=SULF1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: extracellular sulfatase Sulf-1 [Galeopterus variegatus]
ENSG00000137574(TGS1)	--	8.58056	666	8.25684	640	8.27816	635	8.36244	652	8.28729	641	7.06575	548	0.973078376	-0.061339451	normal	0.973641959	-0.019128941	normal	0.942769971	-0.220306806	normal	0.721029296	-0.098021073	normal	--	--	Biological Process: RNA methylation (GO:0001510);; Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: 7-methylguanosine RNA capping (GO:0009452);; 	"K14292|0|hsa:96764|TGS1, NCOA6IP, PIMT, PIPMT; trimethylguanosine synthase 1 (EC:2.1.1.-); K14292 trimethylguanosine synthase [EC:2.1.1.-] (A)"	RNA transport (ko03013)	[R]	General function prediction only	RNA cap guanine-N2 methyltransferase;; Methyltransferase domain;; Methyltransferase domain;; Putative RNA methylase family UPF0020;; Methyltransferase domain;; Met-10+ like-protein	Trimethylguanosine synthase GN=TGS1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: trimethylguanosine synthase isoform X1 [Galeopterus variegatus]
ENSG00000137575(SDCBP)	--	124.6137286	3712	116.1163488	3456	131.5391173	3837	158.423453	4794	137.2807238	4093	190.3796387	5667	0.925435081	0.338077523	normal	0.977511109	0.222539324	normal	0.199448564	0.554134177	normal	0.074180923	0.382643165	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17254|0|pon:100172825|SDCBP; syndecan binding protein (syntenin); K17254 syntenin-1 (A)	--	--	--	PDZ domain (Also known as DHR or GLGF);; PDZ domain	Syntenin-1 GN=SDCBP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: syntenin-1 [Oryctolagus cuniculus]
ENSG00000137601(NEK1)	--	1.696571683	184	1.52342315	167	1.784001162	191	2.243465057	247	2.361005515	211	2.137433887	233	0.828316759	0.391145449	normal	0.906292278	0.313438286	normal	0.922704758	0.276480842	normal	0.294989449	0.329133183	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08857|0|hsa:4750|NEK1, NY-REN-55, SRPS2, SRPS2A, SRTD6; NIMA-related kinase 1 (EC:2.7.11.1); K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)"	--	--	--	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase Nek1 GN=NEK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Nek1 [Ceratotherium simum simum]
ENSG00000137628(DDX60)	--	1.135059004	127	1.358391516	111	1.550459227	137	1.592145024	168	1.784045	140	1.827207	159	0.888891446	0.368909591	normal	0.927653348	0.309676681	normal	0.952346698	0.204462657	normal	0.461641628	0.295380169	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[R]	General function prediction only	"DEAD/DEAH box helicase;; Type III restriction enzyme, res subunit;; Helicase conserved C-terminal domain"	Probable ATP-dependent RNA helicase DDX60 GN=DDX60 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX60-like [Ceratotherium simum simum]
ENSG00000137634(NXPE4)	--	0.032701148	1	0	0	0.033034454	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Neurexophilin;; GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p	NXPE family member 4 (Precursor) GN=NXPE4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: NXPE family member 4-like isoform X1 [Galeopterus variegatus]
ENSG00000137642(SORL1)	--	3.013701	596	3.006012461	609	2.798475612	566	3.239181368	665	3.481685529	668	3.719774959	753	0.96640806	0.126899955	normal	0.967946863	0.111714379	normal	0.712630409	0.40262068	normal	0.321517072	0.215232419	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	"Low-density lipoprotein receptor domain class A;; Fibronectin type III domain;; Low-density lipoprotein receptor repeat class B;; Interferon-alpha/beta receptor, fibronectin type III"	Sortilin-related receptor (Precursor) GN=SORL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: sortilin-related receptor [Galeopterus variegatus]
ENSG00000137648(TMPRSS4)	--	0	0	0.24455275	3	0.057686368	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K09635|0|ptr:451581|TMPRSS4; transmembrane protease, serine 4; K09635 transmembrane protease, serine 4 (A)"	Influenza A (ko05164)	[E]	Amino acid transport and metabolism	Trypsin;; Scavenger receptor cysteine-rich domain;; Domain of unknown function (DUF1986);; Low-density lipoprotein receptor domain class A	Transmembrane protease serine 4 GN=TMPRSS4 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 4 isoform X1 [Equus przewalskii]
ENSG00000137656(BUD13)	--	5.484976579	267	5.406993367	263	4.310102505	209	4.699519	227	5.546755972	269	4.507812472	220	0.924816909	-0.263334036	normal	0.966255993	0.011053968	normal	0.965343256	0.065248926	normal	0.87954993	-0.067197456	normal	--	--	--	K13106|0|ptr:451562|BUD13; BUD13 homolog (S. cerevisiae); K13106 pre-mRNA-splicing factor CWC26 (A)	--	[S]	Function unknown	Pre-mRNA-splicing factor of RES complex	BUD13 homolog GN=BUD13 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: BUD13 homolog [Ursus maritimus]
ENSG00000137672(TRPC6)	--	0.043023972	2	0.086135786	5	0.026411228	1	1.62539803	120	1.210589701	88	1.232144773	95	0	5.079007282	up	2.46E-14	3.76209327	up	0	5.257909755	up	9.50E-23	5.21922414	up	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04969|0|hsa:7225|TRPC6, FSGS2, TRP6; transient receptor potential cation channel, subfamily C, member 6; K04969 transient receptor potential cation channel subfamily C member 6 (A)"	cGMP-PKG signaling pathway (ko04022)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Transient receptor ion channel II;; Ankyrin repeats (3 copies);; Polycystin cation channel;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Short transient receptor potential channel 6 GN=TRPC6 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: short transient receptor potential channel 6 isoform X1 [Oryctolagus cuniculus]
ENSG00000137673(MMP7)	--	10.5414	182	17.6749	308	12.9489	224	51.5457	908	57.3824	986	51.7405	900	0	2.278387495	up	0	1.6524442	up	0	1.99088442	up	3.39E-34	1.946900048	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K01397|0|hsa:4316|MMP7, MMP-7, MPSL1, PUMP-1; matrix metallopeptidase 7 (matrilysin, uterine) (EC:3.4.24.23); K01397 matrix metalloproteinase-7 (matrilysin, uterine) [EC:3.4.24.23] (A)"	Wnt signaling pathway (ko04310)	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Putative peptidoglycan binding domain	Matrilysin (Precursor) GN=MMP7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	matrilysin [Sus scrofa]
ENSG00000137674(MMP20)	--	0	0	0	0	0	0	0.0278487	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K07999|0|hsa:9313|MMP20, AI2A2, MMP-20; matrix metallopeptidase 20; K07999 matrix metalloproteinase-20 (enamelysin) [EC:3.4.24.-] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	Matrix metalloproteinase-20 (Precursor) GN=MMP20 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: matrix metalloproteinase-20 [Tupaia chinensis]
ENSG00000137691(C11orf70)	--	4.755393	71	2.254476621	69	3.626392773	69	5.800293	91	6.721547282	104	4.413676992	66	0.947572445	0.321065731	normal	0.79052336	0.560421178	normal	0.974396605	-0.070834245	normal	0.578617573	0.2986103	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4498)	Uncharacterized protein C11orf70 GN=C11orf70 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C11orf70 homolog isoform X1 [Galeopterus variegatus]
ENSG00000137692(DCUN1D5)	--	28.74911136	594	23.69308163	502	27.54033511	574	32.28501634	685	32.70061006	670	26.78600885	554	0.957821291	0.174388507	normal	0.745757999	0.394016557	normal	0.971534568	-0.05929717	normal	0.47250479	0.171313056	normal	--	--	--	"K17824|1.41952e-176|pps:100994234|DCUN1D5; DCN1, defective in cullin neddylation 1, domain containing 5; K17824 DCN1-like protein 4/5 (A)"	--	[S]	Function unknown	Cullin binding	DCN1-like protein 5 GN=DCUN1D5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DCN1-like protein 5 [Vicugna pacos]
ENSG00000137693(YAP1)	--	22.96431635	1991	23.68522367	2121	21.84957267	1932	24.2158462	2156	22.79730881	2020	23.99290568	2145	0.985295747	0.083969417	normal	0.984569123	-0.091748843	normal	0.980742087	0.14248522	normal	0.872762476	0.043294121	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K16687|0|mcf:102134227|YAP1; Yes-associated protein 1; K16687 protein yorkie (A)	Hippo signaling pathway (ko04390)	[O]	"Posttranslational modification, protein turnover, chaperones"	WW domain	Transcriptional coactivator YAP1 GN=YAP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: yorkie homolog isoform 1 [Orcinus orca]
ENSG00000137699(TRIM29)	--	0.246340521	9	0.2950473	7	0.162825098	5	1.154814791	50	0.792813018	30	0.909209	32	0.0002098	2.262078016	up	0.127936647	1.869287388	normal	0.008548018	2.356312341	up	4.46E-05	2.391525341	up	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	"K12010|0|hsa:23650|TRIM29, ATDC; tripartite motif containing 29; K12010 tripartite motif-containing protein 29 (A)"	--	--	--	B-box zinc finger	Tripartite motif-containing protein 29 GN=TRIM29 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: tripartite motif-containing protein 29 [Chrysochloris asiatica]
ENSG00000137700(SLC37A4)	--	13.40206463	429	10.156998	332	11.40116038	376	13.92722738	443	14.8907233	471	15.60976797	497	0.970324675	0.015442364	normal	0.518724383	0.481268236	normal	0.756967699	0.392843203	normal	0.20953203	0.290685461	normal	[G]	Carbohydrate transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08171|0|ptr:451599|SLC37A4; solute carrier family 37 (glucose-6-phosphate transporter), member 4; K08171 MFS transporter, OPA family, solute carrier family 37 (glycerol-6-phosphate transporter), member 4 (A)"	Carbohydrate digestion and absorption (ko04973)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Glucose-6-phosphate translocase GN=SLC37A4 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: glucose-6-phosphate translocase isoform X1 [Orycteropus afer afer]
ENSG00000137707(BTG4)	--	0.211576813	3	0	0	0.051384575	0	0.136397033	2	0.107756458	0	0.441622825	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K14443|8.71044e-168|hsa:54766|BTG4, PC3B; B-cell translocation gene 4; K14443 protein Tob/BTG (A)"	RNA degradation (ko03018)	[TR]	Signal transduction mechanisms;; General function prediction only	BTG family	Protein BTG4 GN=BTG4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein BTG4 isoform 1 [Ceratotherium simum simum]
ENSG00000137709(POU2F3)	--	0	0	0	0	0	0	0.037172224	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09364|0|hsa:25833|POU2F3, Epoc-1, OCT-11, OCT11, OTF-11, PLA-1, PLA1, Skn-1a; POU class 2 homeobox 3; K09364 POU domain transcription factor, class 2 (A)"	Herpes simplex infection (ko05168)	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 2, transcription factor 3 GN=POU2F3 OS=Homo sapiens (Human) PE=2 SV=3"	K	Transcription	"PREDICTED: POU domain, class 2, transcription factor 3 isoform 1 [Ceratotherium simum simum]"
ENSG00000137710(RDX)	--	40.715101	3342	32.95476435	2689	37.932438	3037	54.045075	4442	67.857028	5528	56.5569184	4610	0.863585844	0.379513625	normal	1.82E-07	1.017853735	up	0.081168852	0.593586797	normal	5.78E-05	0.664216148	normal	--	--	--	K05762|0|ptr:466776|RDX; radixin; K05762 radixin (A)	Regulation of actin cytoskeleton (ko04810);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	[R]	General function prediction only	Ezrin/radixin/moesin family;; FERM C-terminal PH-like domain;; FERM central domain;; FERM N-terminal domain	Radixin GN=RDX OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: radixin isoform 1 [Ceratotherium simum simum]
ENSG00000137713(PPP2R1B)	--	9.578672193	630	9.28067986	577	10.51573194	658	11.95902146	807	12.6345399	795	8.352471863	603	0.865039406	0.325681331	normal	0.605070737	0.439970801	normal	0.965551874	-0.133899439	normal	0.312316077	0.219805915	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03456|0|ptr:466778|PPP2R1B; protein phosphatase 2, regulatory subunit A, beta (EC:3.1.3.16); K03456 serine/threonine-protein phosphatase 2A regulatory subunit A (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	HEAT repeat;; HEAT repeats;; Vacuolar 14 Fab1-binding region;; HEAT-like repeat;; Adaptin N terminal region	Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform GN=PPP2R1B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform isoform 1 [Trichechus manatus latirostris]
ENSG00000137714(FDX1)	--	18.119711	420	18.96463	364	20.39584518	415	16.987907	404	22.76882	455	23.25629287	517	0.966459367	-0.086543459	normal	0.893649202	0.29938704	normal	0.884767694	0.307754822	normal	0.508742812	0.178343263	normal	[C]	Energy production and conversion	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	--	--	[C]	Energy production and conversion	2Fe-2S iron-sulfur cluster binding domain	"Adrenodoxin, mitochondrial (Precursor) GN=FDX1 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: adrenodoxin, mitochondrial [Loxodonta africana]"
ENSG00000137720(C11orf1)	--	12.580361	149	15.8313341	164	17.4297784	166	11.6680487	140	13.806144	159	16.05895	182	0.963532588	-0.119446773	normal	0.964815592	-0.06548232	normal	0.961681434	0.123389888	normal	0.98564369	-0.014292585	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	--	--	--	--	Protein of unknown function (DUF1143)	UPF0686 protein C11orf1 GN=C11orf1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0686 protein C11orf1 homolog isoform X1 [Tupaia chinensis] 
ENSG00000137726(FXYD6)	--	0.0262205	1	0.625349268	5	0	0	15.46637882	115	14.1143346	96	33.18052524	225	0	5.500549445	up	5.55E-16	3.885576706	up	0	7.222599941	up	3.80E-07	6.160994186	up	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	K13363|4.73062e-48|mcf:101867245|FXYD6; FXYD domain-containing ion transport regulator 6; K13363 FXYD domain-containing ion transport regulator 6 (A)	--	--	--	ATP1G1/PLM/MAT8 family	FXYD domain-containing ion transport regulator 6 (Precursor) GN=FXYD6 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: FXYD domain-containing ion transport regulator 6 isoform X2 [Galeopterus variegatus]
ENSG00000137727(ARHGAP20)	--	0.053379449	4	0.019947435	1	0	0	0.00879697	1	0.022585675	1	0.019412608	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Ras association (RalGDS/AF-6) domain	Rho GTPase-activating protein 20 GN=ARHGAP20 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 20 [Equus caballus]
ENSG00000137745(MMP13)	--	0	0	0	0	0.112414013	1	0	0	0.110665901	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	K07994|0|mcc:703980|MMP13; matrix metallopeptidase 13 (collagenase 3); K07994 matrix metalloproteinase-13 (collagenase 3) [EC:3.4.24.-] (A)	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative binding domain;; Putative peptidoglycan binding domain	Collagenase 3 (Precursor) GN=MMP13 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: collagenase 3-like [Myotis lucifugus]
ENSG00000137747(TMPRSS13)	--	0.031479761	2	0	0	0.128936104	6	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K09643|0|hsa:84000|TMPRSS13, MSP, MSPL, MSPS, TMPRSS11; transmembrane protease, serine 13; K09643 transmembrane protease, serine 13 (A)"	Influenza A (ko05164)	[E]	Amino acid transport and metabolism	Trypsin;; Scavenger receptor cysteine-rich domain;; Domain of unknown function (DUF1986)	Transmembrane protease serine 13 GN=TMPRSS13 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: transmembrane protease serine 13, partial [Galeopterus variegatus]"
ENSG00000137752(CASP1)	--	0.086921319	3	0.322728869	10	0.417180397	11	0.922713239	26	1.42672876	45	0.966499017	33	0.020763151	2.576957245	normal	0.003564863	1.994766831	up	0.395849046	1.456155813	normal	0.000401617	2.095955155	up	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K01370|0|ptr:101058924|CASP1; caspase 1, apoptosis-related cysteine peptidase; K01370 caspase 1 [EC:3.4.22.36] (A)"	NOD-like receptor signaling pathway (ko04621);; Cytosolic DNA-sensing pathway (ko04623);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Influenza A (ko05164)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain;; Caspase recruitment domain	Caspase-1 subunit p10 (Precursor) GN=CASP1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-1-like [Balaenoptera acutorostrata scammoni]
ENSG00000137757(CASP5)	--	0	0	0	0	0	0	0.135268676	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K04395|0|pps:100990344|CASP5; caspase 5, apoptosis-related cysteine peptidase; K04395 caspase 5 [EC:3.4.22.58] (A)"	NOD-like receptor signaling pathway (ko04621)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain;; Caspase recruitment domain	Caspase-5 subunit p10 (Precursor) GN=CASP5 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-13-like isoform X3 [Bubalus bubalis]
ENSG00000137760(ALKBH8)	--	3.468862087	240	3.7014909	257	4.066234392	256	3.768031555	246	4.15305803	274	3.74876762	269	0.967083066	0.004761539	normal	0.964173892	0.070578724	normal	0.965690446	0.062808934	normal	0.917111848	0.046528533	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	"Cellular Component: nucleolus (GO:0005730);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (GO:0016706);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K10770|0|hsa:91801|ALKBH8, ABH8; alkB, alkylation repair homolog 8 (E. coli) (EC:2.1.1.229); K10770 alkylated DNA repair protein alkB homolog 8 [EC:1.14.11.- 2.1.1.229] (A)"	--	[S]	Function unknown	2OG-Fe(II) oxygenase superfamily;; Methyltransferase domain;; Domain of unknown function (DUF1891);; Methyltransferase domain;; Methyltransferase domain;; 2OG-Fe(II) oxygenase superfamily;; Methyltransferase domain;; Hypothetical methyltransferase	Alkylated DNA repair protein alkB homolog 8 GN=ALKBH8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: alkylated DNA repair protein alkB homolog 8 [Ceratotherium simum simum]
ENSG00000137764(MAP2K5)	--	14.31678273	548	12.32541479	437	13.72072773	511	14.91165243	577	13.35147905	514	14.3379843	555	0.972121919	0.043444456	normal	0.942897776	0.212031361	normal	0.966662436	0.110559004	normal	0.674624401	0.11661301	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04463|0|pps:100994910|MAP2K5; mitogen-activated protein kinase kinase 5; K04463 mitogen-activated protein kinase kinase 5 [EC:2.7.12.2] (A)	MAPK signaling pathway (ko04010);; Gap junction (ko04540);; Neurotrophin signaling pathway (ko04722);; Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PB1 domain;; Kinase-like	Dual specificity mitogen-activated protein kinase kinase 5 GN=MAP2K5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity mitogen-activated protein kinase kinase 5 isoform 1 [Ceratotherium simum simum]
ENSG00000137766(UNC13C)	--	0	0	0	0	0	0	0.00830672	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	K15293|0|hsa:440279|UNC13C; unc-13 homolog C (C. elegans); K15293 protein unc-13 (A)	Synaptic vesicle cycle (ko04721)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Munc13 (mammalian uncoordinated) homology domain;; Domain of Unknown Function (DUF1041);; C2 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Protein unc-13 homolog C GN=UNC13C OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: protein unc-13 homolog C [Panthera tigris altaica]
ENSG00000137770(CTDSPL2)	--	9.098794097	706	9.915180261	687	8.628473667	649	8.189962	646	8.885595222	620	6.622382583	494	0.962046524	-0.158605272	normal	0.958951957	-0.169076446	normal	0.72201968	-0.400924626	normal	0.264088999	-0.236460466	normal	--	--	--	"K17616|0|hsa:51496|CTDSPL2, HSPC129; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 (EC:3.1.3.-); K17616 CTD small phosphatase-like protein 2 [EC:3.1.3.-] (A)"	--	[K]	Transcription	NLI interacting factor-like phosphatase	CTD small phosphatase-like protein 2 GN=CTDSPL2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CTD small phosphatase-like protein 2 isoform 1 [Ceratotherium simum simum] 
ENSG00000137776(SLTM)	--	26.057126	2345	27.431136	2591	26.4362335	2436	30.92654	2761	29.6441127	2731	32.015546	2829	0.974655549	0.204647031	normal	0.988359485	0.054462777	normal	0.974641494	0.20736704	normal	0.436050688	0.153535388	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; SAP domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	SAFB-like transcription modulator GN=SLTM OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	"PREDICTED: SAFB-like, transcription modulator isoform X7 [Sus scrofa]"
ENSG00000137801(THBS1)	--	8.71107354	1319	13.59623494	2114	10.88620901	1681	17.04532302	2535	16.9180155	2621	8.036973895	1253	7.50E-06	0.910930763	normal	0.942171913	0.288529745	normal	0.628889959	-0.431773157	normal	0.649305813	0.302662199	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Biological Process: cell adhesion (GO:0007155);; 	"K16857|0|hsa:7057|THBS1, THBS, THBS-1, TSP, TSP-1, TSP1; thrombospondin 1; K16857 thrombospondin 1 (A)"	Rap1 signaling pathway (ko04015);; p53 signaling pathway (ko04115);; Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; TGF-beta signaling pathway (ko04350);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Malaria (ko05144);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Bladder cancer (ko05219)	--	--	Thrombospondin C-terminal region;; Thrombospondin type 3 repeat;; Thrombospondin type 1 domain;; von Willebrand factor type C domain;; Complement Clr-like EGF-like;; Calcium-binding EGF domain	Thrombospondin-1 (Precursor) GN=THBS1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: thrombospondin-1 [Vicugna pacos]
ENSG00000137802(MAPKBP1)	--	8.501633198	2059	11.20417615	2448	10.79397133	2303	7.772857493	1854	8.91163518	1997	11.60974576	2449	0.974612234	-0.181991644	normal	0.920076568	-0.314979922	normal	0.986807301	0.080335758	normal	0.593958642	-0.132655603	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Mitogen-activated protein kinase-binding protein 1 GN=MAPKBP1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase-binding protein 1 isoform X2 [Leptonychotes weddellii]
ENSG00000137804(NUSAP1)	--	44.3869345	1891	38.57651633	1612	41.81735882	1752	37.746132	1629	35.638792	1541	39.76811559	1746	0.954516051	-0.245779613	normal	0.981837453	-0.086328596	normal	0.985573707	-0.013229219	normal	0.582625974	-0.117182819	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Biological Process: mitotic cytokinesis (GO:0000281);; Cellular Component: spindle (GO:0005819);; Cellular Component: microtubule (GO:0005874);; Biological Process: establishment of mitotic spindle localization (GO:0040001);; 	--	--	--	--	--	Nucleolar and spindle-associated protein 1 GN=NUSAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nucleolar and spindle-associated protein 1 [Eptesicus fuscus]
ENSG00000137806(NDUFAF1)	--	8.381707412	162	7.886981194	173	7.206423154	156	8.808479351	191	9.10270667	186	8.752977262	191	0.94944698	0.204954919	normal	0.963489068	0.082409196	normal	0.927029727	0.281267081	normal	0.638226796	0.188830347	normal	--	--	--	"K18159|0|hsa:51103|NDUFAF1, CGI65, CIA30; NADH dehydrogenase (ubiquinone) complex I, assembly factor 1; K18159 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 1 (A)"	--	[S]	Function unknown	Complex I intermediate-associated protein 30 (CIA30);; Carbohydrate binding domain (family 11)	"Complex I intermediate-associated protein 30, mitochondrial (Precursor) GN=NDUFAF1 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: complex I intermediate-associated protein 30, mitochondrial [Lipotes vexillifer]"
ENSG00000137807(KIF23)	--	34.36087859	2532	34.73351152	2524	38.15864567	2748	36.05096526	2677	32.73804567	2419	30.67477457	2275	0.988602127	0.049478271	normal	0.986773455	-0.082677092	normal	0.94766194	-0.280636895	normal	0.637294429	-0.103897548	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K17387|0|pps:100975782|KIF23; kinesin family member 23; K17387 kinesin family member 23 (A)	MicroRNAs in cancer (ko05206)	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF23 GN=KIF23 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF23-like [Mustela putorius furo]
ENSG00000137809(ITGA11)	--	0.126609815	16	0.251915391	28	0.10036	19	0.887950698	127	2.38885599	333	1.664345035	214	2.55E-14	2.844450062	up	0	3.48184238	up	0	3.385253092	up	0.000235749	3.399307125	up	--	--	--	"K06587|0|hsa:22801|ITGA11, HsT18964; integrin, alpha 11; K06587 integrin alpha 11 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; von Willebrand factor type A domain;; FG-GAP repeat	Integrin alpha-11 (Precursor) GN=ITGA11 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin alpha-11 isoform X1 [Equus caballus]
ENSG00000137812(KNL1)	--	5.212972229	896	5.713698639	898	5.691131011	970	5.166489636	887	4.997726358	818	4.998314242	889	0.977409885	-0.045318786	normal	0.965707974	-0.155766185	normal	0.970852166	-0.133874673	normal	0.633223924	-0.112655582	normal	--	--	--	"K11542|0|hsa:57082|CASC5, AF15Q14, CT29, D40, KNL1, PPP1R55, Spc7, hKNL-1, hSpc105; cancer susceptibility candidate 5; K11542 protein CASC5 (A)"	--	--	--	--	Protein CASC5 GN=CASC5 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: protein CASC5 [Galeopterus variegatus]
ENSG00000137814(HAUS2)	--	11.6721548	572	10.61770164	611	9.054128	554	15.39058573	720	13.878958	731	8.689674407	504	0.892310465	0.300428946	normal	0.937254216	0.236736183	normal	0.961782112	-0.144340417	normal	0.6301201	0.148334057	normal	--	--	Biological Process: microtubule organizing center organization (GO:0031023);; Biological Process: spindle assembly (GO:0051225);; 	"K16585|6.08645e-163|ptr:741061|HAUS2, CEP27; HAUS augmin-like complex, subunit 2; K16585 HAUS augmin-like complex subunit 2 (A)"	--	--	--	HAUS augmin-like complex subunit 2	HAUS augmin-like complex subunit 2 GN=HAUS2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: HAUS augmin-like complex subunit 2 isoform X1 [Orycteropus afer afer]
ENSG00000137815(RTF1)	--	10.939732	1111	9.368341151	1030	10.02911263	1094	11.54680316	1271	12.45080599	1363	8.930675295	982	0.969891259	0.163062011	normal	0.783833078	0.3822254	normal	0.967657776	-0.163870028	normal	0.577092767	0.138864062	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K15178|0|ptr:740192|RTF1; Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); K15178 RNA polymerase-associated protein RTF1 (A)"	--	[K]	Transcription	Plus-3 domain	RNA polymerase-associated protein RTF1 homolog GN=RTF1 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: RNA polymerase-associated protein RTF1 homolog [Mustela putorius furo]
ENSG00000137817(PARP6)	--	21.88870648	1415	19.40625651	1282	20.80632291	1257	17.57492546	1110	21.64307738	1312	23.65890164	1557	0.780568873	-0.380606692	normal	0.982030568	0.011930988	normal	0.913323609	0.300167789	normal	0.978774325	-0.011173256	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15258|0|hsa:56965|PARP6, ARTD17, PARP-6-B1, PARP-6-C, pART17; poly (ADP-ribose) polymerase family, member 6 (EC:2.4.2.30); K15258 poly [ADP-ribose] polymerase 6/8 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain	Poly [ADP-ribose] polymerase 6 GN=PARP6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: poly [ADP-ribose] polymerase 6 [Chrysochloris asiatica]
ENSG00000137818(RPLP1)	--	1168.773	18266	1160.773	19309	1146.486	18724	1290.051372	22282	1260.841	19911	1277.591	21100	0.99167598	0.25586622	normal	0.997745589	0.022863909	normal	0.996240893	0.164050398	normal	0.543659221	0.147521172	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02942|3.49226e-42|ocu:100342089|RPLP1; ribosomal protein, large, P1; K02942 large subunit ribosomal protein LP1 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	60s Acidic ribosomal protein	60S acidic ribosomal protein P1 GN=RPLP1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S acidic ribosomal protein P1 isoform X1 [Eptesicus fuscus] 
ENSG00000137819(PAQR5)	--	79.96825008	4485	51.20549122	2820	79.87887003	4340	31.9155456	1879	30.15746299	1677	41.7401	2239	6.23E-13	-1.285272238	down	0.000877187	-0.770696697	normal	8.63E-07	-0.962656228	normal	0.002220701	-1.027136639	down	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Membrane progestin receptor gamma GN=PAQR5 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: membrane progestin receptor gamma isoform X1 [Galeopterus variegatus]
ENSG00000137821(LRRC49)	--	6.213489126	327	6.813189969	337	7.221894171	335	5.216859008	239	6.906122757	333	5.049472811	257	0.585989925	-0.480459563	normal	0.966883427	-0.038479262	normal	0.797743492	-0.388674887	normal	0.277492135	-0.289935243	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K16606|0|hsa:54839|LRRC49, PGs4; leucine rich repeat containing 49; K16606 leucine-rich repeat-containing protein 49 (A)"	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 49 GN=LRRC49 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 49 isoform X3 [Equus caballus]
ENSG00000137822(TUBGCP4)	--	4.454244	328	4.209361053	309	4.823170588	377	4.178340691	311	4.286938	347	4.361164	323	0.962828632	-0.10709819	normal	0.956906832	0.145231267	normal	0.93557102	-0.230322587	normal	0.855595278	-0.068437824	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: spindle pole (GO:0000922);; Cellular Component: microtubule organizing center (GO:0005815);; Biological Process: microtubule nucleation (GO:0007020);; Molecular Function: gamma-tubulin binding (GO:0043015);; 	"K16571|0|pps:100975360|TUBGCP4; tubulin, gamma complex associated protein 4; K16571 gamma-tubulin complex component 4 (A)"	--	[Z]	Cytoskeleton	Spc97 / Spc98 family	Gamma-tubulin complex component 4 GN=TUBGCP4 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: gamma-tubulin complex component 4 isoform 1 [Dasypus novemcinctus]
ENSG00000137824(RMDN3)	--	8.390178877	348	8.558717	352	10.25454	382	13.3085269	522	11.88710574	502	11.353536	447	0.242719528	0.552127777	normal	0.480712461	0.488918069	normal	0.940675667	0.217613592	normal	0.0434216	0.42161897	normal	--	--	--	--	--	--	--	TPR repeat	Regulator of microtubule dynamics protein 3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: regulator of microtubule dynamics protein 3 isoform X1 [Felis catus]
ENSG00000137825(ITPKA)	--	2.062291509	74	1.885393314	67	2.647311	80	2.22454556	80	2.007853995	65	1.581896956	53	0.972778462	0.080043919	normal	0.973599069	-0.063688367	normal	0.837292711	-0.588535601	normal	0.785295833	-0.180741607	normal	--	--	"Molecular Function: inositol-1,4,5-trisphosphate 3-kinase activity (GO:0008440);; "	K00911|0|nle:100590762|ITPKA; inositol-trisphosphate 3-kinase A; K00911 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] (A)	Inositol phosphate metabolism (ko00562);; Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070)	[I]	Lipid transport and metabolism	Inositol polyphosphate kinase	Inositol-trisphosphate 3-kinase A GN=ITPKA OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	inositol-trisphosphate 3-kinase A [Bos taurus] 
ENSG00000137831(UACA)	--	16.77755096	2071	12.65129898	1564	15.52688486	1902	30.068358	3939	23.240264	3013	16.00147245	2029	1.03E-05	0.896179737	normal	6.84E-06	0.923878942	normal	0.984717393	0.084894814	normal	0.147367455	0.674780639	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Uveal autoantigen with coiled-coil domains and ankyrin repeats GN=UACA OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	uveal autoantigen [Bos taurus]
ENSG00000137834(SMAD6)	--	22.968427	2355	24.537886	2698	24.274995	2575	17.7853	1804	20.504	2043	21.698755	2193	0.715429721	-0.41504954	normal	0.719693618	-0.422354682	normal	0.964101904	-0.239805276	normal	0.021469353	-0.357333801	normal	--	--	"Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K04677|0|hsa:4091|SMAD6, AOVD2, HsT17432, MADH6, MADH7; SMAD family member 6; K04677 mothers against decapentaplegic homolog 6/7 (A)"	Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain	Mothers against decapentaplegic homolog 6 GN=SMAD6 OS=Homo sapiens (Human) PE=1 SV=2	KT	Transcription;; Signal transduction mechanisms	PREDICTED: mothers against decapentaplegic homolog 6 [Eptesicus fuscus]
ENSG00000137841(PLCB2)	--	0.029025142	3	0.019495423	2	0.030431339	2	0.071113541	7	0.028989663	2	0.009836237	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: lipid catabolic process (GO:0016042);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05858|0|pps:100969344|PLCB2; phospholipase C, beta 2; K05858 phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Chemokine signaling pathway (ko04062);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Huntington's disease (ko05016);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Pathways in cancer (ko05200)	[I]	Lipid transport and metabolism	"Phosphatidylinositol-specific phospholipase C, X domain;; PLC-beta C terminal;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 GN=PLCB2 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2 isoform X1 [Mustela putorius furo] "
ENSG00000137842(TMEM62)	--	5.68084186	237	5.9851562	252	6.87881666	284	9.83826	376	9.547726	392	10.042489	400	0.122533748	0.631735908	normal	0.158968536	0.613031526	normal	0.532597689	0.483637433	normal	0.008355706	0.574770991	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	--	--	--	Transmembrane protein 62 GN=TMEM62 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 62 [Galeopterus variegatus]
ENSG00000137843(PAK6)	--	16.73012509	1315	16.67265959	1307	17.26841994	1338	15.37774796	1210	13.78770033	1079	12.10851582	941	0.972870799	-0.150704374	normal	0.911599844	-0.297611175	normal	0.271296852	-0.515404593	normal	0.058581185	-0.315874948	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05735|0|hsa:56924|PAK6, PAK5; p21 protein (Cdc42/Rac)-activated kinase 6 (EC:2.7.11.1); K05735 p21-activated kinase 6 [EC:2.7.11.1] (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Axon guidance (ko04360);; Focal adhesion (ko04510);; T cell receptor signaling pathway (ko04660);; Regulation of actin cytoskeleton (ko04810);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; P21-Rho-binding domain;; Kinase-like	Serine/threonine-protein kinase PAK 6 GN=PAK6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase PAK 6 isoform X1 [Tupaia chinensis]
ENSG00000137845(ADAM10)	--	69.15751728	5431	68.588136	5983	61.51672194	5104	77.91111223	5967	71.06506455	5458	69.08029795	6027	0.992559923	0.104927325	normal	0.990145122	-0.153882484	normal	0.981624918	0.231457116	normal	0.82617788	0.057937177	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K06704|0|ptr:746942|ADAM10; ADAM metallopeptidase domain 10; K06704 disintegrin and metalloproteinase domain-containing protein 10 [EC:3.4.24.81] (A)	Alzheimer's disease (ko05010)	[W]	Extracellular structures	Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Disintegrin;; Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease	Disintegrin and metalloproteinase domain-containing protein 10 (Precursor) GN=ADAM10 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: disintegrin and metalloproteinase domain-containing protein 10 [Tupaia chinensis]
ENSG00000137857(DUOX1)	--	0.0896001	8	0.0110134	1	0.0650011	5	0.0224433	2	0.035898658	3	0.0333687	3	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13411|0|hsa:53905|DUOX1, LNOX1, NOXEF1, THOX1; dual oxidase 1 (EC:1.6.3.1); K13411 dual oxidase [EC:1.6.3.1 1.11.1.-] (A)"	--	[PQ]	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Animal haem peroxidase;; Ferric reductase NAD binding domain;; FAD-binding domain;; Ferric reductase like transmembrane component;; EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand;; Oxidoreductase NAD-binding domain	Dual oxidase 1 (Precursor) GN=DUOX1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual oxidase 1 [Ceratotherium simum simum]
ENSG00000137860(SLC28A2)	--	0.055361864	4	0.041043064	3	0.013673113	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	--	"K11536|0|hsa:9153|SLC28A2, CNT2, HCNT2, HsT17153, SPNT1; solute carrier family 28 (concentrative nucleoside transporter), member 2; K11536 pyrimidine nucleoside transport protein (A)"	--	[FP]	Nucleotide transport and metabolism;; Inorganic ion transport and metabolism	Na+ dependent nucleoside transporter C-terminus;; Na+ dependent nucleoside transporter N-terminus;; Nucleoside recognition	Sodium/nucleoside cotransporter 2 GN=SLC28A2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	Sodium/nucleoside cotransporter 2 [Tupaia chinensis]
ENSG00000137868(STRA6)	--	31.44901659	1545	22.30103326	923	27.03598527	1261	22.65047403	1097	40.66260412	1994	20.08313196	1001	0.235863346	-0.524253472	normal	2.70E-08	1.088593846	up	0.855443708	-0.340957732	normal	0.900535826	0.113106443	normal	--	--	--	--	--	--	--	Retinol binding protein receptor	Stimulated by retinoic acid gene 6 protein homolog GN=STRA6 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: stimulated by retinoic acid gene 6 protein homolog isoform X1 [Vicugna pacos]
ENSG00000137871(ZNF280D)	--	14.825704	891	14.977284	923	13.929659	882	13.402996	871	13.857892	888	12.899588	844	0.976465237	-0.063474266	normal	0.975536324	-0.077068779	normal	0.97583126	-0.071701409	normal	0.787087247	-0.0719646	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF4195)	Zinc finger protein 280D GN=ZNF280D OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 280D isoform X3 [Equus przewalskii]
ENSG00000137872(SEMA6D)	--	0	0	0	0	0.028045503	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06842|0|mcc:713885|SEMA6D; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D; K06842 semaphorin 6 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-6D (Precursor) GN=SEMA6D OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-6D isoform 1 [Equus caballus] 
ENSG00000137875(BCL2L10)	--	0.106752869	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K18451|2.78241e-90|hsa:10017|BCL2L10, BCL-B, Boo, Diva; BCL2-like 10 (apoptosis facilitator); K18451 Bcl-2-like protein 10 (A)"	--	--	--	"Apoptosis regulator proteins, Bcl-2 family"	Bcl-2-like protein 10 GN=BCL2L10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: bcl-2-like protein 10 [Oryctolagus cuniculus]
ENSG00000137876(RSL24D1)	--	113.6521837	2888	110.2757666	2951	112.0735559	2698	103.321793	2662	89.27047284	2455	117.949851	3068	0.983907572	-0.148310217	normal	0.947577963	-0.286746083	normal	0.981098528	0.177023584	normal	0.725058255	-0.081695423	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02896|8.89553e-104|pon:100174234|RSL24D1, C15orf15; ribosomal L24 domain containing 1; K02896 large subunit ribosomal protein L24e (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L24e	Probable ribosome biogenesis protein RLP24 GN=RSL24D1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: probable ribosome biogenesis protein RLP24-like [Chrysochloris asiatica]
ENSG00000137877(SPTBN5)	--	0.0781133	22	0.0477324	14	0.0700438	20	0.014181	4	0.027637	7	0.0176012	5	0.242805773	-2.11341146	normal	--	--	--	0.669984899	-1.73096205	normal	--	--	--	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K06115|0|hsa:51332|SPTBN5, BSPECV, HUBSPECV, HUSPECV; spectrin, beta, non-erythrocytic 5; K06115 spectrin beta (A)"	--	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; CAMSAP CH domain	"Spectrin beta chain, non-erythrocytic 5 GN=SPTBN5 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: spectrin beta chain, non-erythrocytic 5 [Galeopterus variegatus]"
ENSG00000137878(GCOM1)	--	25.10457498	1390	22.96197312	1258	23.69620127	1326	25.17822892	1467	28.18637106	1544	25.62451623	1482	0.982825957	0.04690126	normal	0.934391124	0.273816715	normal	0.974343421	0.152009168	normal	0.435584475	0.155979935	normal	--	--	"Cellular Component: DNA-directed RNA polymerase II, holoenzyme (GO:0016591);; "	--	--	--	--	Putative GRINL1B complex locus protein 2	Myocardial zonula adherens protein (Precursor) GN=MYZAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DNA-directed RNA polymerase II subunit GRINL1A-like isoform X2 [Tupaia chinensis]
ENSG00000137880(GCHFR)	--	2.11387	24	1.577218	16	1.653103	17	5.656859	62	9.264211	103	8.299482	93	0.069352776	1.285493793	normal	1.71E-10	2.556886825	up	1.29E-08	2.344132261	up	4.21E-07	2.158206933	up	--	--	--	--	--	--	--	GTP cyclohydrolase I feedback regulatory protein (GFRP)	GTP cyclohydrolase 1 feedback regulatory protein GN=GCHFR OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: GTP cyclohydrolase 1 feedback regulatory protein [Ceratotherium simum simum] 
ENSG00000137936(BCAR3)	--	12.25444891	840	9.795575951	679	12.72811532	897	23.77034406	1660	22.75107428	1577	19.10985352	1340	3.10E-06	0.950630389	normal	8.35E-10	1.192479885	up	0.111919131	0.569970339	normal	3.77E-09	0.90032893	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	--	--	SH2 domain;; RasGEF domain	Breast cancer anti-estrogen resistance protein 3 GN=BCAR3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: breast cancer anti-estrogen resistance protein 3 isoform X1 [Equus caballus] 
ENSG00000137941(TTLL7)	--	2.2885561	236	2.34550165	255	2.525804204	242	1.608232991	180	1.889282444	196	1.305243821	140	0.792801572	-0.418491685	normal	0.812476623	-0.398366895	normal	0.030297273	-0.791288632	normal	0.052910679	-0.528275203	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16583|0|hsa:79739|TTLL7; tubulin tyrosine ligase-like family, member 7; K16583 tubulin polyglutamylase TTLL7 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin polyglutamylase TTLL7 GN=TTLL7 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: tubulin polyglutamylase TTLL7-like [Tupaia chinensis]
ENSG00000137942(FNBP1L)	--	13.216396	1174	12.44181169	1064	13.11130981	1082	13.03706221	1114	11.77287951	998	11.89873965	1028	0.976736046	-0.106372499	normal	0.974228158	-0.113646166	normal	0.977667816	-0.082034031	normal	0.663532087	-0.101928022	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	"Fes/CIP4, and EFC/F-BAR homology domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Bacterial SH3 domain"	Formin-binding protein 1-like GN=FNBP1L OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: formin binding protein 1-like isoform X3 [Canis lupus familiaris]
ENSG00000137944(KYAT3)	--	14.23657218	479	11.03366784	428	10.90658072	398	11.17663128	440	11.51980924	444	14.44364107	531	0.958661012	-0.152842648	normal	0.969246201	0.031413346	normal	0.720692622	0.406310963	normal	0.755663259	0.095909587	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00816|0|hsa:56267|CCBL2, KAT3, KATIII; cysteine conjugate-beta lyase 2 (EC:2.6.1.7 4.4.1.13 2.6.1.63); K00816 kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64] (A)"	Tryptophan metabolism (ko00380);; Selenocompound metabolism (ko00450);; Chemical carcinogenesis (ko05204)	[E]	Amino acid transport and metabolism	Aminotransferase class I and II;; Cys/Met metabolism PLP-dependent enzyme	Kynurenine--oxoglutarate transaminase 3 GN=CCBL2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: kynurenine--oxoglutarate transaminase 3 [Felis catus] 
ENSG00000137947(GTF2B)	--	7.998002864	174	8.167077455	178	9.273044213	195	11.41334478	254	9.709777846	204	11.77196632	256	0.579996018	0.511153743	normal	0.952996933	0.173884581	normal	0.835386154	0.381786556	normal	0.227631145	0.36329959	normal	[K]	Transcription	Molecular Function: TBP-class protein binding (GO:0017025);; 	K03124|0|umr:103662925|GTF2B; general transcription factor IIB; K03124 transcription initiation factor TFIIB (A)	Basal transcription factors (ko03022);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	"Transcription factor TFIIB repeat;; TFIIB zinc-binding;; Cyclin, N-terminal domain"	Transcription initiation factor IIB GN=GTF2B OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	transcription initiation factor IIB [Bos taurus] 
ENSG00000137955(RABGGTB)	--	28.12612256	589	25.44425608	512	32.38715	598	31.25454	628	27.248181	549	24.1991552	489	0.972139353	0.061509266	normal	0.968827628	0.079010388	normal	0.893959909	-0.297768249	normal	0.881309871	-0.050076893	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; 	"K05956|0|ptr:100614714|RABGGTB; Rab geranylgeranyltransferase, beta subunit; K05956 geranylgeranyl transferase type-2 subunit beta [EC:2.5.1.60] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prenyltransferase and squalene oxidase repeat;; Prenyltransferase-like;; Prenyltransferase-like	Geranylgeranyl transferase type-2 subunit beta GN=RABGGTB OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: geranylgeranyl transferase type-2 subunit beta [Panthera tigris altaica]
ENSG00000137959(IFI44L)	--	0.031837003	3	0	0	0.085054447	7	0.223094435	22	0.312878359	30	0.124625343	12	0.141739578	2.350657755	normal	8.86E-06	4.370948265	up	--	--	--	--	--	--	--	--	Molecular Function: GTP binding (GO:0005525);; 	--	--	--	--	--	Interferon-induced protein 44-like GN=IFI44L OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: interferon-induced protein 44-like [Physeter catodon]
ENSG00000137960(GIPC2)	--	0	0	0.019003	1	0	0	0	0	0	0	0.0192312	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PDZ domain (Also known as DHR or GLGF)	PDZ domain-containing protein GIPC2 GN=GIPC2 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PDZ domain-containing protein GIPC2 isoformX1 [Sus scrofa]
ENSG00000137962(ARHGAP29)	--	8.67519698	931	8.764360103	929	11.48114042	1093	12.99943846	1407	8.6659089	916	9.986693798	1041	0.123077452	0.564174812	normal	0.977465008	-0.041689211	normal	0.978035435	-0.078503463	normal	0.658860259	0.165974121	normal	--	--	Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Rho GTPase-activating protein 29 GN=ARHGAP29 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 29 isoform X1 [Equus przewalskii]
ENSG00000137965(IFI44)	--	0.351648045	8	0.047975743	1	0.185735793	4	1.665524095	42	2.541789109	62	1.273233285	25	0.002440307	2.162893533	up	1.68E-12	4.645252568	up	0.081578368	2.259020716	normal	0.000279971	3.288857132	up	--	--	--	--	--	--	--	TLD	Interferon-induced protein 44 GN=IFI44 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: interferon-induced protein 44 [Galeopterus variegatus]
ENSG00000137968(SLC44A5)	--	0.686578	42	0.522065	31	0.512676	31	0.428994	26	0.725584	42	0.321045	20	0.91790135	-0.690308838	normal	0.966999814	0.3998819	normal	0.963051097	-0.603631284	normal	0.75598694	-0.262712635	normal	--	--	--	"K15377|0|ptr:456953|SLC44A5; solute carrier family 44, member 5; K15377 solute carrier family 44 (choline transporter-like protein), member 2/4/5 (A)"	Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Plasma-membrane choline transporter	Choline transporter-like protein 5 GN=SLC44A5 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: choline transporter-like protein 5 isoform X2 [Tupaia chinensis]
ENSG00000137975(CLCA2)	--	0.013719	1	0	0	0	0	0.0136948	1	0	0	0.0272287	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05028|0|hsa:9635|CLCA2, CACC, CACC3, CLCRG2, CaCC-3; chloride channel accessory 2; K05028 calcium-activated chloride channel regulator 2 (A)"	Olfactory transduction (ko04740);; Pancreatic secretion (ko04972)	--	--	Calcium-activated chloride channel;; Domain of unknown function (DUF1973);; von Willebrand factor type A domain;; von Willebrand factor type A domain	"Calcium-activated chloride channel regulator 2, 35 kDa form (Precursor) GN=CLCA2 OS=Homo sapiens (Human) PE=1 SV=2"	W	Extracellular structures	PREDICTED: calcium-activated chloride channel regulator 2 [Ceratotherium simum simum]
ENSG00000137992(DBT)	--	3.025980441	399	4.316661711	487	4.576238503	491	3.39017022	492	3.818311521	487	3.99471942	503	0.914410512	0.270497944	normal	0.9705775	-0.021360229	normal	0.971473484	0.026463403	normal	0.786144857	0.085036694	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K09699|0|hsa:1629|DBT, BCATE2, BCKAD-E2, BCKADE2, E2, E2B; dihydrolipoamide branched chain transacylase E2 (EC:2.3.1.168); K09699 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase) [EC:2.3.1.168] (A)"	"Valine, leucine and isoleucine degradation (ko00280)"	[C]	Energy production and conversion	2-oxoacid dehydrogenases acyltransferase (catalytic domain);; Biotin-requiring enzyme;; e3 binding domain	"Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial (Precursor) GN=DBT OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000137996(RTCA)	--	15.6894981	588	14.84792547	552	14.6748642	551	14.32367808	540	13.8924082	527	15.469896	573	0.960748943	-0.153270911	normal	0.968297282	-0.088044963	normal	0.972037372	0.048062018	normal	0.833277129	-0.065254749	normal	[A]	RNA processing and modification	--	"K01974|0|hsa:8634|RTCA, RPC, RTC1, RTCD1; RNA 3'-terminal phosphate cyclase (EC:6.5.1.4); K01974 RNA 3'-terminal phosphate cyclase (ATP) [EC:6.5.1.4] (A)"	--	[A]	RNA processing and modification	"RNA 3'-terminal phosphate cyclase;; RNA 3'-terminal phosphate cyclase (RTC), insert domain"	RNA 3'-terminal phosphate cyclase GN=RTCA OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA 3'-terminal phosphate cyclase isoform X4 [Bubalus bubalis]
ENSG00000138002(IFT172)	--	4.1202272	457	3.883601	460	4.256652	496	3.510549	381	3.393368235	373	3.998025011	440	0.898869964	-0.292157872	normal	0.871299914	-0.322704198	normal	0.952913649	-0.180543208	normal	0.260824799	-0.263596039	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[K]	Transcription	"Region in Clathrin and VPS;; WD domain, G-beta repeat"	Intraflagellar transport protein 172 homolog GN=IFT172 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: intraflagellar transport protein 172 homolog [Equus caballus] 
ENSG00000138018(SELENOI)	--	19.02815	2135	20.49209	2357	19.71790443	2213	18.67493431	2082	17.687534	1957	15.00060133	1717	0.986189874	-0.0670494	normal	0.93841021	-0.289530353	normal	0.823407112	-0.374113798	normal	0.162257761	-0.241969048	normal	--	--	"Biological Process: phospholipid biosynthetic process (GO:0008654);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, for other substituted phosphate groups (GO:0016780);; "	"K00993|0|ptr:100286802|EPT1, SELI; ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific) (EC:2.7.8.1); K00993 ethanolaminephosphotransferase [EC:2.7.8.1] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565)	[I]	Lipid transport and metabolism	CDP-alcohol phosphatidyltransferase	Ethanolaminephosphotransferase 1 GN=EPT1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	ethanolaminephosphotransferase 1 [Oryctolagus cuniculus]
ENSG00000138028(CGREF1)	--	6.487363873	256	6.311446488	266	4.706011	224	3.76541501	132	3.672147274	144	2.42046373	103	0.000871042	-0.978105817	normal	0.003688977	-0.899718822	normal	0.00013611	-1.11773712	down	8.32E-05	-0.999034173	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	EF-hand domain pair;; EF-hand domain	Cell growth regulator with EF hand domain protein 1 (Precursor) GN=CGREF1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: cell growth regulator with EF hand domain protein 1 [Galeopterus variegatus]
ENSG00000138029(HADHB)	--	83.585345	2474	76.225647	2437	72.126597	2223	68.207324	2059	67.5525966	2076	78.8475416	2140	0.934570139	-0.295532405	normal	0.958505146	-0.252556347	normal	0.986656629	-0.063144809	normal	0.251231883	-0.206339293	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	"K07509|0|hsa:3032|HADHB, ECHB, MTPB, TP-BETA; hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (EC:2.3.1.16); K07509 acetyl-CoA acyltransferase [EC:2.3.1.16] (A)"	"Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	"Thiolase, N-terminal domain;; Thiolase, C-terminal domain;; Beta-ketoacyl synthase, N-terminal domain"	3-ketoacyl-CoA thiolase (Precursor) GN=HADHB OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	"PREDICTED: trifunctional enzyme subunit beta, mitochondrial [Equus przewalskii] "
ENSG00000138030(KHK)	--	9.43464	430	7.076670007	332	10.2978044	484	5.273964003	242	4.880413108	220	4.767764	218	0.001233959	-0.856024751	normal	0.197115688	-0.611658022	normal	3.86E-07	-1.153456074	down	0.000141465	-0.894734091	normal	[G]	Carbohydrate transport and metabolism	--	K00846|0|pon:100447147|KHK; ketohexokinase (fructokinase) (EC:2.7.1.3); K00846 ketohexokinase [EC:2.7.1.3] (A)	Fructose and mannose metabolism (ko00051)	[G]	Carbohydrate transport and metabolism	pfkB family carbohydrate kinase	Ketohexokinase GN=KHK OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: ketohexokinase isoform X2 [Condylura cristata]
ENSG00000138031(ADCY3)	--	46.7048494	2947	38.580807	2742	38.27379142	2883	37.4734642	2122	33.12303492	2109	28.903761	1709	0.347112223	-0.504343227	normal	0.788164479	-0.399843784	normal	0.000827789	-0.762184544	normal	0.000115791	-0.550903137	normal	[T]	Signal transduction mechanisms	Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	K08043|0|pps:100995134|ADCY3; adenylate cyclase 3; K08043 adenylate cyclase 3 [EC:4.6.1.1] (A)	Purine metabolism (ko00230);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; GABAergic synapse (ko04727);; Olfactory transduction (ko04740);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Vasopressin-regulated water reabsorption (ko04962);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Morphine addiction (ko05032);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[C]	Energy production and conversion	Adenylate and Guanylate cyclase catalytic domain	Adenylate cyclase type 3 GN=ADCY3 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: adenylate cyclase type 3 [Tupaia chinensis]
ENSG00000138032(PPM1B)	--	25.00051187	1206	27.75211708	1399	27.27263609	1324	20.92490725	1043	20.43029266	975	21.60490933	1036	0.946000914	-0.239993868	normal	0.200683471	-0.541642936	normal	0.820390733	-0.36170229	normal	0.01586663	-0.384700771	normal	[T]	Signal transduction mechanisms	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: phosphoprotein phosphatase activity (GO:0004721);; Molecular Function: manganese ion binding (GO:0030145);; 	"K04461|0|pps:100970133|PPM1B; protein phosphatase, Mg2+/Mn2+ dependent, 1B; K04461 protein phosphatase 1B [EC:3.1.3.16] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	"Protein phosphatase 2C;; Protein serine/threonine phosphatase 2C, C-terminal domain;; Protein phosphatase 2C"	Protein phosphatase 1B GN=PPM1B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1B isoform X1 [Galeopterus variegatus] 
ENSG00000138035(PNPT1)	--	22.736141	1355	26.48868588	1511	23.33085599	1339	22.079619	1202	19.59245598	1139	16.3764599	1033	0.962032444	-0.203443097	normal	0.651188753	-0.428666513	normal	0.775005983	-0.382114367	normal	0.037026234	-0.339423465	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: 3'-5'-exoribonuclease activity (GO:0000175);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; 	"K00962|0|hsa:87178|PNPT1, COXPD13, DFNB70, OLD35, PNPASE, old-35; polyribonucleotide nucleotidyltransferase 1 (EC:2.7.7.8); K00962 polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA degradation (ko03018)	[R]	General function prediction only	"3' exoribonuclease family, domain 1;; 3' exoribonuclease family, domain 2;; Polyribonucleotide nucleotidyltransferase, RNA binding domain;; KH domain;; S1 RNA binding domain"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial (Precursor) GN=PNPT1 OS=Homo sapiens (Human) PE=1 SV=2"	A	RNA processing and modification	"PREDICTED: polyribonucleotide nucleotidyltransferase 1, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000138036(DYNC2LI1)	--	12.83377712	279	8.220830921	177	12.25420138	272	10.21608454	236	8.31501804	182	9.287241568	207	0.920394021	-0.270687413	normal	0.965841296	0.018605766	normal	0.803381736	-0.399711694	normal	0.542395782	-0.241373846	normal	--	--	--	"K10417|0|hsa:51626|DYNC2LI1, D2LIC, LIC3; dynein, cytoplasmic 2, light intermediate chain 1; K10417 dynein light intermediate chain 2, cytosolic (A)"	Vasopressin-regulated water reabsorption (ko04962)	[S]	Function unknown	Dynein light intermediate chain (DLIC)	Cytoplasmic dynein 2 light intermediate chain 1 GN=DYNC2LI1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: cytoplasmic dynein 2 light intermediate chain 1 isoform X2 [Mustela putorius furo] 
ENSG00000138050(THUMPD2)	--	9.357759	326	8.9682778	306	7.864182	277	6.935571	241	7.659906	268	6.986123586	253	0.63365404	-0.464116131	normal	0.94161143	-0.211606767	normal	0.958585907	-0.138249966	normal	0.328786743	-0.275704849	normal	[L]	"Replication, recombination and repair"	Molecular Function: RNA binding (GO:0003723);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	--	--	Putative RNA methylase family UPF0020;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase small domain;; THUMP domain;; ubiE/COQ5 methyltransferase family	THUMP domain-containing protein 2 GN=THUMPD2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: THUMP domain-containing protein 2 [Orcinus orca]
ENSG00000138061(CYP1B1)	--	44.8014604	3647	26.86212028	2204	24.69392249	2006	19.24492857	1585	27.56122447	2261	17.65301971	1450	1.01E-11	-1.232248027	down	0.987475823	0.015399778	normal	0.448795277	-0.476136033	normal	0.307401819	-0.590796636	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07410|0|hsa:1545|CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1; cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1); K07410 cytochrome P450, family 1, subfamily B, polypeptide 1 [EC:1.14.14.1] (A)"	Steroid hormone biosynthesis (ko00140);; Tryptophan metabolism (ko00380);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Ovarian steroidogenesis (ko04913);; Chemical carcinogenesis (ko05204);; MicroRNAs in cancer (ko05206)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 1B1 GN=CYP1B1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 1B1 [Galeopterus variegatus]
ENSG00000138069(RAB1A)	--	133.9452214	4429	146.906659	4885	141.39132	4493	121.7737342	3885	114.8758984	3753	123.95406	4005	0.979567073	-0.219817166	normal	0.835888097	-0.401598533	normal	0.986038178	-0.174106154	normal	0.121275256	-0.267136325	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07874|1.18215e-150|rno:81754|Rab1a, Ac2-048, Rab1, Rab1r; RAB1A, member RAS oncogene family; K07874 Ras-related protein Rab-1A (A)"	Legionellosis (ko05134)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase;; Signal recognition particle receptor beta subunit	Ras-related protein Rab-1A GN=RAB1A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	"Ras-related protein Rab-1A, partial [Bos mutus]"
ENSG00000138071(ACTR2)	--	170.7670409	9772	176.1230607	10162	180.1182316	10158	166.3169778	9643	150.7820542	8603	136.2570535	7797	0.995975296	-0.049996166	normal	0.9834481	-0.261656807	normal	0.906656252	-0.389850333	normal	0.238320253	-0.230299609	normal	--	--	--	K17260|0|tup:102474683|actin-related protein 2-like; K17260 actin-related protein 2 (A)	--	[Z]	Cytoskeleton	Actin	Actin-related protein 2 GN=ACTR2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: actin-related protein 2 isoform X1 [Orycteropus afer afer]
ENSG00000138073(PREB)	--	39.12326641	1401	32.18360013	1246	39.64037425	1488	27.92835544	1003	31.69523437	1100	27.89107739	1003	0.280370199	-0.512300136	normal	0.960991919	-0.200967299	normal	0.096381806	-0.576625804	normal	0.004880375	-0.433730233	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14003|0|hsa:10113|PREB, SEC12; prolactin regulatory element binding; K14003 prolactin regulatory element-binding protein (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"WD domain, G-beta repeat"	Prolactin regulatory element-binding protein GN=PREB OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: prolactin regulatory element-binding protein [Pteropus alecto] 
ENSG00000138074(SLC5A6)	--	33.29358102	1256	31.653637	1210	31.967214	1318	19.368967	801	21.402852	862	19.549725	864	0.010712897	-0.678745289	normal	0.315530179	-0.509914847	normal	0.043927955	-0.616658025	normal	4.84E-05	-0.603296794	normal	[ER]	Amino acid transport and metabolism;; General function prediction only	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14386|0|hsa:8884|SLC5A6, SMVT; solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6; K14386 solute carrier family 5 (sodium-dependent multivitamin transporter), member 6 (A)"	Vitamin digestion and absorption (ko04977)	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium-dependent multivitamin transporter GN=SLC5A6 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent multivitamin transporter isoform X7 [Tupaia chinensis] 
ENSG00000138078(PREPL)	--	29.30712815	2179	31.63956373	2223	30.61298107	2230	19.29382441	1437	17.38533902	1290	19.56399135	1471	0.028332938	-0.630886256	normal	0.000332729	-0.805834427	normal	0.048808597	-0.608026452	normal	1.02E-06	-0.680891199	normal	[E]	Amino acid transport and metabolism	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Molecular Function: serine-type exopeptidase activity (GO:0070008);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Prolyl oligopeptidase family;; Prolyl oligopeptidase, N-terminal beta-propeller domain"	Prolyl endopeptidase-like GN=PREPL OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prolyl endopeptidase-like isoformX2 [Equus caballus] 
ENSG00000138079(SLC3A1)	--	0.987916792	23	1.174203	22	0.8723277	20	0.5959338	17	0.6486965	19	0.183558516	8	0.983186853	-0.433150383	normal	0.986446869	-0.216874213	normal	0.921010626	-1.184637652	normal	0.484059674	-0.585972917	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K14210|0|hsa:6519|SLC3A1, ATR1, CSNU1, D2H, NBAT, RBAT; solute carrier family 3 (amino acid transporter heavy chain), member 1; K14210 solute carrier family 3 (neutral and basic amino acid transporter), member 1 (A)"	Protein digestion and absorption (ko04974)	[G]	Carbohydrate transport and metabolism	"Alpha amylase, catalytic domain"	Neutral and basic amino acid transport protein rBAT GN=SLC3A1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: neutral and basic amino acid transport protein rBAT [Tupaia chinensis]
ENSG00000138080(EMILIN1)	--	0.780851528	33	0.33745608	28	0.381973174	18	0.68912089	21	0.67364501	29	0.562976046	28	0.954418792	-0.644954529	normal	0.984479354	0.027727982	normal	0.969781089	0.589175127	normal	0.98598528	-0.039464022	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	EMI domain;; C1q domain;; Collagen triple helix repeat (20 copies)	EMILIN-1 (Precursor) GN=EMILIN1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: EMILIN-1 [Ceratotherium simum simum]
ENSG00000138081(FBXO11)	--	24.65121208	1717	26.49357501	1852	26.89030249	1852	20.5178124	1412	20.77325001	1443	20.83802527	1441	0.90488469	-0.312673085	normal	0.804365094	-0.381085804	normal	0.820776656	-0.369961784	normal	0.023169802	-0.3566308	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	K10297|0|ggo:101147773|FBXO11; F-box only protein 11 isoform 1; K10297 F-box protein 11 (A)	--	[R]	General function prediction only	Right handed beta helix region;; Periplasmic copper-binding protein (NosD);; F-box-like;; Putative zinc finger in N-recognin (UBR box);; F-box domain	F-box only protein 11 GN=FBXO11 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: F-box only protein 11 [Erinaceus europaeus]
ENSG00000138083(SIX3)	--	0.390766	15	0.289088	11	0.380865	14	0.600679	23	0.648319	25	0.10178	4	0.980252447	0.540841906	normal	0.901292344	1.063795233	normal	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox domain;; Homeobox KN domain	Homeobox protein SIX3 GN=SIX3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: homeobox protein SIX3 [Lipotes vexillifer]
ENSG00000138085(ATRAID)	--	127.05466	2049	106.13241	1722	118.715395	1979	92.344826	1522	95.155214	1525	87.522561	1450	0.52524553	-0.459382531	normal	0.968310461	-0.196518926	normal	0.536429201	-0.456600824	normal	0.015238114	-0.375794346	normal	--	--	--	--	--	--	--	--	All-trans retinoic acid-induced differentiation factor (Precursor) GN=ATRAID OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: all-trans retinoic acid-induced differentiation factor [Felis catus]
ENSG00000138092(CENPO)	--	14.0557	1168	13.77529	1152	15.0625	1253	11.73879	970	11.07088	907	9.70854	806	0.905396239	-0.298384421	normal	0.812849277	-0.365850119	normal	0.02474867	-0.643849164	normal	0.005840365	-0.434880703	normal	--	--	Cellular Component: kinetochore (GO:0000776);; Biological Process: centromere complex assembly (GO:0034508);; 	K11507|0|ptr:738568|CENPO; centromere protein O; K11507 centromere protein O (A)	--	--	--	Cenp-O kinetochore centromere component	Centromere protein O GN=CENPO OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein O [Galeopterus variegatus]
ENSG00000138095(LRPPRC)	--	88.98072844	8602	93.37990249	9184	88.94609458	8502	70.243123	6943	68.92653865	6565	63.37893519	6158	0.949646196	-0.339877497	normal	0.531856647	-0.505655205	normal	0.646842794	-0.473532419	normal	0.006357677	-0.440344042	normal	--	--	--	"K17964|0|hsa:10128|LRPPRC, CLONE-23970, GP130, LRP130, LSFC; leucine-rich pentatricopeptide repeat containing; K17964 leucine-rich PPR motif-containing protein, mitochondrial (A)"	--	[A]	RNA processing and modification	PPR repeat family;; PPR repeat;; Pentatricopeptide repeat domain;; PPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	"Leucine-rich PPR motif-containing protein, mitochondrial (Precursor) GN=LRPPRC OS=Homo sapiens (Human) PE=1 SV=3"	A	RNA processing and modification	"PREDICTED: leucine-rich PPR motif-containing protein, mitochondrial [Ceratotherium simum simum]"
ENSG00000138100(TRIM54)	--	0.024625663	1	0	0	0.070094728	2	0	0	0	0	0.072805164	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10653|0|hsa:57159|TRIM54, MURF, MURF-3, RNF30, muRF3; tripartite motif containing 54; K10653 tripartite motif-containing protein 54 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; RING-type zinc-finger;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; B-box zinc finger"	Tripartite motif-containing protein 54 GN=TRIM54 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 54 [Tupaia chinensis]
ENSG00000138101(DTNB)	--	6.9716278	348	5.220765	261	6.562088762	322	3.761271617	183	4.477602855	235	3.4805152	184	0.000338518	-0.952173143	normal	0.951861711	-0.171766155	normal	0.008541389	-0.810544025	normal	0.005435648	-0.649899531	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[Z]	Cytoskeleton	"EF hand;; EF-hand;; Zinc finger, ZZ type"	Dystrobrevin beta GN=DTNB OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: dystrobrevin beta isoform X1 [Tupaia chinensis]
ENSG00000138107(ACTR1A)	--	49.059627	2625	43.598149	2358	53.56501497	2891	62.101046	3340	61.66992	3268	53.821367	2879	0.928913796	0.316533845	normal	0.64010157	0.449172024	normal	0.98989548	-0.014284774	normal	0.150149796	0.247543897	normal	[Z]	Cytoskeleton	--	"K16575|0|umr:103680932|ACTR1A; ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); K16575 centractin (A)"	--	[Z]	Cytoskeleton	Actin	Alpha-centractin GN=ACTR1A OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	Alpha-centractin [Pteropus alecto]
ENSG00000138111(MFSD13A)	--	5.763152	181	6.459252802	178	8.151525978	200	2.970196	101	5.295452836	142	5.472202	144	0.028875549	-0.86251906	normal	0.896808789	-0.344131745	normal	0.725915379	-0.477944069	normal	0.077184764	-0.550405675	normal	--	--	--	--	--	--	--	MFS/sugar transport protein	Transmembrane protein 180 GN=TMEM180 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 180 [Trichechus manatus latirostris]
ENSG00000138119(MYOF)	--	115.253291	15341	134.948219	18504	124.7128	17315	116.214053	16530	86.311574	11900	121.090734	16685	0.997141017	0.076854518	normal	0.046453946	-0.658234491	normal	0.997381113	-0.061756648	normal	0.437085453	-0.202715695	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	C2 domain;; FerB (NUC096) domain;; FerI (NUC094) domain;; FerA (NUC095) domain	Myoferlin GN=MYOF OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: myoferlin isoform X3 [Oryctolagus cuniculus]
ENSG00000138131(LOXL4)	--	2.486742657	186	1.952154626	151	2.080419498	158	1.66867364	124	2.55533827	193	2.1507619	163	0.42471207	-0.609581893	normal	0.901522794	0.329698772	normal	0.967108872	0.036313754	normal	0.902498766	-0.064749569	normal	--	--	"Molecular Function: scavenger receptor activity (GO:0005044);; Molecular Function: copper ion binding (GO:0005507);; Cellular Component: membrane (GO:0016020);; Molecular Function: oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor (GO:0016641);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00280|0|hsa:84171|LOXL4, LOXC; lysyl oxidase-like 4; K00280 lysyl oxidase-like protein 2/3/4 [EC:1.4.3.-] (A)"	--	--	--	Lysyl oxidase;; Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	Lysyl oxidase homolog 4 (Precursor) GN=LOXL4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lysyl oxidase homolog 4 [Oryctolagus cuniculus]
ENSG00000138134(STAMBPL1)	--	10.33143113	497	9.579954053	454	11.97363979	581	12.025586	581	11.34341346	543	11.79333244	589	0.950460067	0.193905228	normal	0.933714469	0.236113396	normal	0.973427693	0.011408535	normal	0.590941452	0.140317932	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11867|0|pps:100988185|STAMBPL1; STAM binding protein-like 1; K11867 AMSH-like protease [EC:3.4.19.12] (A)	--	[T]	Signal transduction mechanisms	JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; USP8 dimerisation domain;; Prokaryotic homologs of the JAB domain	AMSH-like protease GN=STAMBPL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: AMSH-like protease isoform 1 [Dasypus novemcinctus] 
ENSG00000138135(CH25H)	--	0	0	0	0	0.0475249	0	0.0476199	1	0.0932186	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: iron ion binding (GO:0005506);; Biological Process: lipid biosynthetic process (GO:0008610);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K10223|1.0147e-175|hsa:9023|CH25H, C25H; cholesterol 25-hydroxylase (EC:1.14.99.38); K10223 cholesterol 25-hydroxylase [EC:1.14.99.38] (A)"	Primary bile acid biosynthesis (ko00120)	[I]	Lipid transport and metabolism	Fatty acid hydroxylase superfamily	Cholesterol 25-hydroxylase GN=CH25H OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: cholesterol 25-hydroxylase [Galeopterus variegatus] 
ENSG00000138138(ATAD1)	--	34.68976046	1385	42.63647164	1713	36.11406654	1422	39.75294876	1695	43.4021218	1722	50.81034262	2070	0.944025338	0.260305658	normal	0.985002833	-0.013854368	normal	0.2121161	0.53294542	normal	0.205967189	0.258896388	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain;; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (dynein-related subfamily)	ATPase family AAA domain-containing protein 1 GN=ATAD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	ATPase family AAA domain-containing protein 1 [Myotis brandtii]
ENSG00000138152(BTBD16)	--	0.1109919	2	0.2432408	4	0.1678964	3	0.447641	10	0.877523	13	0.2259771	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10487|0|hsa:118663|BTBD16, C10orf87; BTB (POZ) domain containing 16; K10487 BTB/POZ domain-containing protein 16 (A)"	--	[R]	General function prediction only	--	BTB/POZ domain-containing protein 16 GN=BTBD16 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: BTB/POZ domain-containing protein 16 [Trichechus manatus latirostris]
ENSG00000138160(KIF11)	--	26.7902	2376	23.5728	2074	26.4667	2287	26.02173	2326	25.17435	2232	21.53287	1917	0.987397983	-0.061475823	normal	0.985335432	0.08443522	normal	0.951723165	-0.262707468	normal	0.737792794	-0.078886681	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: structural molecule activity (GO:0005198);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10398|0|hsa:3832|KIF11, EG5, HKSP, KNSL1, MCLMR, TRIP5; kinesin family member 11; K10398 kinesin family member 11 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain;; Kinesin-associated microtubule-binding	Kinesin-like protein KIF11 GN=KIF11 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF11 [Galeopterus variegatus]
ENSG00000138161(CUZD1)	--	7.57587467	304	7.469155228	264	7.338578576	350	8.672437896	331	11.5109216	336	7.663604319	280	0.964305007	0.091484459	normal	0.878098937	0.324843858	normal	0.872786823	-0.328628561	normal	0.962336181	0.023653553	normal	--	--	--	--	--	--	--	Zona pellucida-like domain;; CUB domain	CUB and zona pellucida-like domain-containing protein 1 (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: CUB and zona pellucida-like domain-containing protein 1-like [Dasypus novemcinctus]
ENSG00000138162(TACC2)	--	15.43396565	1299	18.09773233	1623	15.58580445	1395	11.90284627	866	12.76536304	1161	18.6291214	1578	0.045034896	-0.614897287	normal	0.340033015	-0.504163338	normal	0.972449493	0.169367909	normal	0.504966001	-0.279559671	normal	--	--	--	"K14282|0|pps:100983705|TACC2; transforming, acidic coiled-coil containing protein 2; K14282 transforming acidic coiled-coil-containing protein 2 (A)"	--	--	--	Transforming acidic coiled-coil-containing protein (TACC)	Transforming acidic coiled-coil-containing protein 2 GN=TACC2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transforming acidic coiled-coil-containing protein 2 isoform X10 [Equus caballus]
ENSG00000138166(DUSP5)	--	16.3787	713	27.6344	1221	21.9533	970	12.6707	554	8.90375	388	31.0509	1360	0.735291205	-0.393882497	normal	0	-1.671479926	down	0.423095813	0.47862547	normal	0.739936328	-0.353605139	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K04459|0|hsa:1847|DUSP5, DUSP, HVH3; dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48); K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 5 GN=DUSP5 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 5 [Sus scrofa]
ENSG00000138172(CALHM2)	--	0.823345849	25	0.9043639	28	0.566493542	17	2.143503007	66	1.942419	60	1.522882	48	0.037602421	1.318101229	normal	0.353847346	1.038944684	normal	0.105673889	1.41147726	normal	0.008194803	1.290797676	up	--	--	--	--	--	--	--	Calcium homeostasis modulator	Calcium homeostasis modulator protein 2 GN=CALHM2 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: calcium homeostasis modulator protein 2 [Loxodonta africana] 
ENSG00000138175(ARL3)	--	25.74698269	776	26.13919574	806	27.60014469	840	22.18381715	772	24.86421917	862	22.27568	688	0.975965242	-0.038212215	normal	0.974588787	0.075344761	normal	0.899921042	-0.295682975	normal	0.75579935	-0.082161389	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07944|1.64156e-116|pps:100987836|ARL3; ADP-ribosylation factor-like 3; K07944 ADP-ribosylation factor-like protein 3 (A)	--	[R]	General function prediction only	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; G-protein alpha subunit;; Ras family;; Gtr1/RagA G protein conserved region;; Miro-like protein;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain;; ATPase family associated with various cellular activities (AAA)	ADP-ribosylation factor-like protein 3 GN=ARL3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	ADP-ribosylation factor-like protein 3 [Sus scrofa] 
ENSG00000138180(CEP55)	--	46.30400119	2459	45.1361035	2387	49.10130202	2569	42.45760183	2260	32.91660585	1747	33.10280134	1761	0.981512586	-0.152481802	normal	0.509656926	-0.471394873	normal	0.155752218	-0.552708039	normal	0.012233493	-0.384309751	normal	--	--	--	"K16456|0|hsa:55165|CEP55, C10orf3, CT111, URCC6; centrosomal protein 55kDa; K16456 centrosomal protein CEP55 (A)"	--	--	--	TSG101 and ALIX binding domain of CEP55	Centrosomal protein of 55 kDa GN=CEP55 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: centrosomal protein of 55 kDa isoform X1 [Oryctolagus cuniculus]
ENSG00000138182(KIF20B)	--	12.5347948	1484	12.31681294	1616	15.23050041	1694	16.16131452	1883	13.13924485	1545	12.34352492	1555	0.908185053	0.312421938	normal	0.981876505	-0.086164441	normal	0.978943551	-0.13168799	normal	0.900909615	0.034088367	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10402|0|hsa:9585|KIF20B, CT90, KRMP1, MPHOSPH1, MPP-1, MPP1; kinesin family member 20B; K10402 kinesin family member 20 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF20B GN=KIF20B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF20B isoform X3 [Galeopterus variegatus]
ENSG00000138185(ENTPD1)	--	1.289979465	117	1.348840102	119	1.5081868	134	0.7559201	67	0.893720029	78	0.93672	88	0.209311177	-0.820674001	normal	0.634158826	-0.621018876	normal	0.609562956	-0.606441162	normal	0.063020744	-0.687321966	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K01510|0|pps:100971059|ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1; K01510 apyrase [EC:3.6.1.5] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Epstein-Barr virus infection (ko05169)	[F]	Nucleotide transport and metabolism	GDA1/CD39 (nucleoside phosphatase) family	Ectonucleoside triphosphate diphosphohydrolase 1 GN=ENTPD1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: ectonucleoside triphosphate diphosphohydrolase 1 [Galeopterus variegatus]
ENSG00000138190(EXOC6)	--	11.22188097	666	11.78679219	694	12.77618354	739	21.93075711	741	22.64411405	726	13.69345735	810	0.968357997	0.122850342	normal	0.974210807	0.043514618	normal	0.969646657	0.123814015	normal	0.713277133	0.09663537	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: vesicle docking involved in exocytosis (GO:0006904);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex subunit Sec15-like	Exocyst complex component 6 GN=EXOC6 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 6 isoform 2 [Ceratotherium simum simum]
ENSG00000138193(PLCE1)	--	3.84128821	788	3.38124406	684	3.954992005	784	4.598769937	964	5.22633311	1016	4.98991386	990	0.9298356	0.259547109	normal	0.192493116	0.548404782	normal	0.86710389	0.32771967	normal	0.027069521	0.375754408	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05860|0|ptr:450620|PLCE1; phospholipase C, epsilon 1; K05860 phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Phosphatidylinositol signaling system (ko04070);; Thyroid hormone signaling pathway (ko04919);; Proteoglycans in cancer (ko05205)	--	--	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; RasGEF domain;; Ras association (RalGDS/AF-6) domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 GN=PLCE1 OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform 2 [Ceratotherium simum simum]"
ENSG00000138207(RBP4)	--	1.720658004	30	3.402072093	50	1.9689486	33	5.875615	103	7.684311911	135	6.259482542	112	1.40E-05	1.699058494	up	8.43E-05	1.385048921	up	4.05E-06	1.709611899	up	1.01E-05	1.609756606	up	--	--	--	"K18271|1.89492e-142|ptr:450617|RBP4; retinol binding protein 4, plasma; K18271 retinol-binding protein 4 (A)"	--	--	--	Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin-like domain	Plasma retinol-binding protein(1-176) (Precursor) GN=RBP4 OS=Homo sapiens (Human) PE=1 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: retinol-binding protein 4 [Mustela putorius furo] 
ENSG00000138231(DBR1)	--	7.588349109	333	7.652700568	341	6.885268953	302	7.52497	332	7.867594	342	6.067577235	267	0.967834406	-0.035009426	normal	0.967536868	-0.017126133	normal	0.949903987	-0.185014251	normal	0.844886194	-0.074634532	normal	--	--	"Biological Process: mRNA processing (GO:0006397);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	K18328|0|hsa:51163|DBR1; debranching RNA lariats 1; K18328 lariat debranching enzyme [EC:3.1.-.-] (A)	--	[A]	RNA processing and modification	"Lariat debranching enzyme, C-terminal domain;; Calcineurin-like phosphoesterase"	Lariat debranching enzyme GN=DBR1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: lariat debranching enzyme [Galeopterus variegatus]
ENSG00000138246(DNAJC13)	--	12.4537	1820	14.6458	2142	12.5938	1814	11.038	1619	10.603	1543	14.8563	2171	0.968756834	-0.199489035	normal	0.39653608	-0.494233848	normal	0.955684834	0.250702539	normal	0.67972844	-0.135648301	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09533|0|hsa:23317|DNAJC13, RME8; DnaJ (Hsp40) homolog, subfamily C, member 13; K09533 DnaJ homolog subfamily C member 13 (A)"	--	[UO]	"Intracellular trafficking, secretion, and vesicular transport;; Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; Domain of unknown function (DUF4339)	DnaJ homolog subfamily C member 13 GN=DNAJC13 OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 13 [Ursus maritimus]
ENSG00000138271(GPR87)	--	0.167759	4	0.138623	3	0.0458413	0	0.792175	19	0.998065	22	0.372666	9	--	--	--	0.123235152	2.364340611	normal	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08389|0|hsa:53836|GPR87, GPR95, KPG_002; G protein-coupled receptor 87; K08389 G protein-coupled receptor 87 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 87 GN=GPR87 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 87 [Orycteropus afer afer]
ENSG00000138279(ANXA7)	--	80.82669324	2111	80.74909655	2133	77.74026958	2123	68.501992	2170	77.26027146	2157	65.28244791	2118	0.987471581	0.00892979	normal	0.987169492	-0.005280624	normal	0.98738253	-0.011684891	normal	0.993303525	-0.003690255	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	K17095|0|mcc:707166|ANXA7; annexin A7; K17095 annexin A7/11 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A7 GN=ANXA7 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A7 isoform X1 [Capra hircus]
ENSG00000138286(FAM149B1)	--	5.155216922	369	5.4277588	419	3.608245653	344	4.8861558	393	5.066001	394	5.64717374	356	0.967692808	0.05983481	normal	0.963268088	-0.109772508	normal	0.968053852	0.041000049	normal	0.989936683	-0.007769334	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3719)	Protein FAM149B1 GN=FAM149B1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM149B1 [Camelus dromedarius]
ENSG00000138303(ASCC1)	--	34.88089673	1049	32.49976214	959	32.94445511	935	20.95931514	668	23.78325825	737	24.2379086	724	0.011787169	-0.680666033	normal	0.725511892	-0.400569896	normal	0.777798056	-0.376573981	normal	0.002436695	-0.488132935	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K18666|0|hsa:51008|ASCC1, ASC1p50, p50; activating signal cointegrator 1 complex subunit 1; K18666 activating signal cointegrator complex subunit 1 (A)"	--	[K]	Transcription	AKAP7 2'5' RNA ligase-like domain;; KH domain;; KH domain	Activating signal cointegrator 1 complex subunit 1 GN=ASCC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: activating signal cointegrator 1 complex subunit 1 [Oryctolagus cuniculus] 
ENSG00000138308(PLA2G12B)	--	0	0	0	0	0	0	0.0548976	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipase A2 activity (GO:0004623);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid catabolic process (GO:0016042);; 	"K01047|2.10889e-137|hsa:84647|PLA2G12B, GXIIB, GXIIIsPLA2, PLA2G13; phospholipase A2, group XIIB (EC:3.1.1.4); K01047 secretory phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; Pancreatic secretion (ko04972);; Fat digestion and absorption (ko04975)	--	--	Group XII secretory phospholipase A2 precursor (PLA2G12)	Group XIIB secretory phospholipase A2-like protein (Precursor) GN=PLA2G12B OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: group XIIB secretory phospholipase A2-like protein [Odobenus rosmarus divergens]
ENSG00000138311(ZNF365)	--	1.469182	72	1.225195702	64	0.99799124	70	1.611493403	97	1.479459086	100	0.896114813	50	0.924532762	0.391928037	normal	0.738070321	0.610797273	normal	0.920922119	-0.481356602	normal	0.679827713	0.239173787	normal	--	--	--	"K16737|0|hsa:22891|ZNF365, Su48, UAN, ZNF365D; zinc finger protein 365; K16737 protein ZNF365 (A)"	--	--	--	--	Protein ZNF365 GN=ZNF365 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	Protein ZNF365 [Tupaia chinensis]
ENSG00000138315(OIT3)	--	0	0	0.158996	7	0.035910672	0	0.0913332	4	0.0883034	3	0.112874475	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zona pellucida-like domain;; Coagulation Factor Xa inhibitory site	Oncoprotein-induced transcript 3 protein (Precursor) GN=OIT3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oncoprotein-induced transcript 3 protein [Tupaia chinensis]
ENSG00000138316(ADAMTS14)	--	0.05142307	6	0.01681313	2	0.00823662	0	0.0516124	6	0.07512838	8	0.02545389	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08628|0|hsa:140766|ADAMTS14; ADAM metallopeptidase with thrombospondin type 1 motif, 14; K08628 a disintegrin and metalloproteinase with thrombospondin motifs 14 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin family propeptide;; Thrombospondin type 1 domain;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 14 (Precursor) GN=ADAMTS14 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 14 isoform X2 [Tupaia chinensis]
ENSG00000138326(RPS24)	--	2026.962773	9660	2003.402063	9555	1994.537973	9630	2308.258769	12025	2186.467015	10694	2263.595189	11235	0.980650137	0.285068833	normal	0.994199648	0.14102614	normal	0.990436945	0.214069827	normal	0.288074742	0.213827732	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02974|0|pps:100968788|RPS24; ribosomal protein S24; K02974 small subunit ribosomal protein S24e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S24e	40S ribosomal protein S24 GN=RPS24 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	40S ribosomal protein S24 isoform 5 [Canis lupus familiaris] 
ENSG00000138336(TET1)	--	0.826867389	112	0.82671694	118	1.244899333	129	0.704690135	105	0.746200267	110	0.894028044	121	0.96648147	-0.122209723	normal	0.964377485	-0.121101973	normal	0.966166082	-0.099451416	normal	0.835971011	-0.11608521	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	"K13097|0|hsa:80312|TET1, CXXC6, LCX, bA119F7.1; tet methylcytosine dioxygenase 1 (EC:1.14.11.n2); K13097 methylcytosine dioxygenase [EC:1.14.11.-] (A)"	--	--	--	Oxygenase domain of the 2OGFeDO superfamily;; CXXC zinc finger domain	Methylcytosine dioxygenase TET1 GN=TET1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: methylcytosine dioxygenase TET1 [Ceratotherium simum simum]
ENSG00000138347(MYPN)	--	0.555664478	120	0.79862053	195	0.836769019	205	1.471414005	358	1.34996495	268	2.26560352	473	9.59E-11	1.534177259	up	0.749140268	0.434447521	normal	1.56E-07	1.191969947	up	0.018486762	1.059581554	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Myopalladin GN=MYPN OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: myopalladin isoform X1 [Leptonychotes weddellii] 
ENSG00000138356(AOX1)	--	2.877872	208	2.160266683	155	3.2377717	228	10.8524074	781	10.16999819	709	6.100656964	436	0	1.870267619	up	0	2.161283418	up	0.000280635	0.922502343	normal	9.78E-05	1.68210714	up	[F]	Nucleotide transport and metabolism	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: metal ion binding (GO:0046872);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00157|0|hsa:316|AOX1, AO, AOH1; aldehyde oxidase 1 (EC:1.2.3.1); K00157 aldehyde oxidase [EC:1.2.3.1] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Tyrosine metabolism (ko00350);; Tryptophan metabolism (ko00380);; Vitamin B6 metabolism (ko00750);; Nicotinate and nicotinamide metabolism (ko00760);; Retinol metabolism (ko00830);; Drug metabolism - cytochrome P450 (ko00982)"	[F]	Nucleotide transport and metabolism	"Molybdopterin-binding domain of aldehyde dehydrogenase;; FAD binding domain in molybdopterin dehydrogenase;; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;; [2Fe-2S] binding domain;; CO dehydrogenase flavoprotein C-terminal domain;; 2Fe-2S iron-sulfur cluster binding domain"	Aldehyde oxidase GN=AOX1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: aldehyde oxidase-like [Tupaia chinensis]
ENSG00000138363(ATIC)	--	88.53342253	3412	93.48676776	3759	90.16627506	3606	55.18864737	2223	55.14263465	2201	52.53463825	2111	0.019247001	-0.64857709	normal	0.000443445	-0.793194036	normal	0.000470638	-0.780331312	normal	6.98E-08	-0.74304046	normal	[F]	Nucleotide transport and metabolism	Molecular Function: IMP cyclohydrolase activity (GO:0003937);; Molecular Function: phosphoribosylaminoimidazolecarboxamide formyltransferase activity (GO:0004643);; Biological Process: purine nucleotide biosynthetic process (GO:0006164);; 	K00602|0|pps:100993618|ATIC; 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] (A)	Purine metabolism (ko00230);; One carbon pool by folate (ko00670)	[F]	Nucleotide transport and metabolism	AICARFT/IMPCHase bienzyme;; MGS-like domain	IMP cyclohydrolase GN=ATIC OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: bifunctional purine biosynthesis protein PURH isoform X2 [Mustela putorius furo]
ENSG00000138375(SMARCAL1)	--	14.38012858	802	9.675586514	564	12.82010533	696	7.072632333	417	6.415220774	372	7.920868312	438	7.66E-06	-0.971756344	normal	0.089240243	-0.619757197	normal	0.021957309	-0.67458332	normal	0.000596387	-0.769897778	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K14440|0|hsa:50485|SMARCAL1, HARP, HHARP; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; K14440 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 [EC:3.6.4.12] (A)"	--	[B]	Chromatin structure and dynamics	HepA-related protein (HARP);; SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 GN=SMARCAL1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000138376(BARD1)	--	5.555009951	439	5.785179235	452	6.156419758	479	3.909381567	293	3.35028667	260	2.985069792	219	0.125461212	-0.611513243	normal	0.003099612	-0.815591781	normal	7.58E-07	-1.131964234	down	1.44E-05	-0.849433586	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10683|0|hsa:580|BARD1; BRCA1 associated RING domain 1; K10683 BRCA1-associated RING domain protein 1 [EC:6.3.2.19] (A)	--	--	--	zf-RING of BARD1-type protein;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; BRCA1 C Terminus (BRCT) domain	BRCA1-associated RING domain protein 1 GN=BARD1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: BRCA1-associated RING domain protein 1 isoform X1 [Physeter catodon]
ENSG00000138378(STAT4)	--	6.805084984	247	6.335596735	258	7.523675641	215	5.221347745	188	7.303963569	242	7.035043029	258	0.780668617	-0.421594074	normal	0.960497479	-0.113105873	normal	0.930248566	0.253115619	normal	0.83571174	-0.086088577	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	K11222|0|ptr:100610925|STAT4; signal transducer and activator of transcription 4; K11222 signal transducer and activator of transcription 4 (A)	Jak-STAT signaling pathway (ko04630);; Hepatitis B (ko05161);; Inflammatory bowel disease (IBD) (ko05321)	[KT]	Transcription;; Signal transduction mechanisms	"STAT protein, DNA binding domain;; STAT protein, all-alpha domain;; STAT protein, protein interaction domain;; SH2 domain"	Signal transducer and activator of transcription 4 GN=STAT4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: signal transducer and activator of transcription 4 isoform X1 [Oryctolagus cuniculus] 
ENSG00000138379(MSTN)	--	0.0227897	1	0.0460222	2	0	0	0.0675366	3	0	0	0.0225302	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K05497|0|ggo:101135255|MSTN; growth/differentiation factor 8; K05497 growth differentiation factor 8/11 (A)	--	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Growth/differentiation factor 8 (Precursor) GN=MSTN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: growth/differentiation factor 8 [Galeopterus variegatus]
ENSG00000138380(CARF)	--	3.369611723	195	2.424310438	181	1.7239409	136	1.658253616	107	1.402698486	108	1.590553184	120	0.014855988	-0.887110629	normal	0.117841403	-0.758090683	normal	0.957643033	-0.186652581	normal	0.046729969	-0.633364075	normal	--	--	--	--	--	--	--	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8	Calcium-responsive transcription factor GN=CARF OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein [Ceratotherium simum simum]
ENSG00000138381(ASNSD1)	--	22.63231195	877	24.63539465	942	21.25704755	822	16.40576338	632	16.73321246	659	17.87935029	697	0.336648764	-0.502442416	normal	0.233538654	-0.535840763	normal	0.935038355	-0.245779535	normal	0.010980722	-0.430848923	normal	[E]	Amino acid transport and metabolism	Molecular Function: asparagine synthase (glutamine-hydrolyzing) activity (GO:0004066);; Biological Process: asparagine biosynthetic process (GO:0006529);; 	--	--	[E]	Amino acid transport and metabolism	Asparagine synthase;; Glutamine amidotransferase domain	Asparagine synthetase domain-containing protein 1 GN=ASNSD1 OS=Homo sapiens (Human) PE=2 SV=2	E	Amino acid transport and metabolism	PREDICTED: asparagine synthetase domain-containing protein 1 [Trichechus manatus latirostris]
ENSG00000138382(METTL5)	--	50.05950617	540	45.00491184	509	50.10210857	580	34.28885372	373	36.41296423	392	34.20874912	369	0.200904092	-0.562677569	normal	0.750280775	-0.39689065	normal	0.039016942	-0.658552026	normal	0.004370924	-0.543560304	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Methyltransferase small domain;; Methyltransferase domain;; Methyltransferase domain;; Ribosomal protein L11 methyltransferase (PrmA);; Putative RNA methylase family UPF0020;; Methyltransferase domain;; Conserved hypothetical protein 95;; RNA cap guanine-N2 methyltransferase;; Methyltransferase domain;; Methyltransferase domain	Methyltransferase-like protein 5 GN=METTL5 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	hypothetical protein PANDA_004629 [Ailuropoda melanoleuca]
ENSG00000138385(SSB)	--	96.591314	3071	100.914985	3272	120.2603101	3794	71.445188	2364	67.846604	2163	59.577964	1910	0.762952755	-0.408077272	normal	0.04935464	-0.618211527	normal	2.35E-07	-0.997866658	normal	2.87E-06	-0.676678336	normal	[OJ]	"Posttranslational modification, protein turnover, chaperones;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	K11090|0|pps:100978413|SSB; Sjogren syndrome antigen B (autoantigen La); K11090 lupus La protein (A)	Systemic lupus erythematosus (ko05322)	[A]	RNA processing and modification	"RNA binding motif;; La domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Lupus La protein GN=SSB OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: lupus La protein homolog isoform 1 [Equus caballus] 
ENSG00000138386(NAB1)	--	19.86040516	1299	16.86764816	1256	18.12104369	1309	13.00338578	966	15.03004909	1004	14.93802949	1063	0.510923594	-0.457508476	normal	0.854780405	-0.344039346	normal	0.899420936	-0.308219046	normal	0.021502562	-0.370195426	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	--	--	[K]	Transcription	Conserved region in Nab1;; NAB conserved region 2 (NCD2);; NAB conserved region 1 (NCD1)	NGFI-A-binding protein 1 GN=NAB1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: NGFI-A-binding protein 1 isoform X1 [Elephantulus edwardii]
ENSG00000138395(CDK15)	--	0.101904357	5	0	0	0.029377642	1	0.014704517	1	0.04093322	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K15594|0|hsa:65061|CDK15, ALS2CR7, PFTAIRE2, PFTK2; cyclin-dependent kinase 15 (EC:2.7.11.22); K15594 cyclin-dependent kinase 15 [EC:2.7.11.22] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 15 GN=CDK15 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 15 isoform 2 [Trichechus manatus latirostris]
ENSG00000138398(PPIG)	--	19.36626233	1415	23.52812259	1682	20.37402063	1557	16.74305459	1209	16.29739391	1270	14.34205904	1059	0.941139869	-0.257517176	normal	0.66603046	-0.426333039	normal	0.122481503	-0.5636897	normal	0.006562436	-0.417079327	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K09566|0|hsa:9360|PPIG, CARS-Cyp, CYP, SCAF10, SRCyp; peptidylprolyl isomerase G (cyclophilin G) (EC:5.2.1.8); K09566 peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase G GN=PPIG OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase G isoform X1 [Leptonychotes weddellii]
ENSG00000138399(FASTKD1)	--	13.97374675	631	14.93571887	628	13.45642608	538	10.32796693	464	11.12116001	486	10.142937	418	0.484639818	-0.472998403	normal	0.755803766	-0.390163544	normal	0.796129212	-0.371207626	normal	0.031807658	-0.415238183	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; 	--	--	--	--	"FAST kinase-like protein, subdomain 2;; FAST kinase-like protein, subdomain 1;; RAP domain"	FAST kinase domain-containing protein 1 GN=FASTKD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: FAST kinase domain-containing protein 1 [Galeopterus variegatus] 
ENSG00000138400(MDH1B)	--	1.322328902	46	1.170722	43	1.505019	52	0.73371	27	0.752726	27	0.7602713	29	0.866270672	-0.765731832	normal	0.918318964	-0.663114235	normal	0.782298117	-0.818448653	normal	0.165652897	-0.785194608	normal	[C]	Energy production and conversion	--	--	--	[C]	Energy production and conversion	"lactate/malate dehydrogenase, alpha/beta C-terminal domain"	Putative malate dehydrogenase 1B GN=MDH1B OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: putative malate dehydrogenase 1B isoform X1 [Galeopterus variegatus]
ENSG00000138411(HECW2)	--	2.271537579	175	2.006805517	247	2.3017959	209	2.1899041	141	2.590491666	170	1.664870668	141	0.902685884	-0.339167061	normal	0.456762186	-0.556272147	normal	0.481440692	-0.571035794	normal	0.092265435	-0.50249487	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	K12168|0|ggo:101143182|HECW2; E3 ubiquitin-protein ligase HECW2; K12168 E3 ubiquitin-protein ligase HECW2 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain;; C2 domain	E3 ubiquitin-protein ligase HECW2 GN=HECW2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase HECW2 isoform X1 [Tupaia chinensis]
ENSG00000138413(IDH1)	--	135.1224459	5494	136.1262244	5624	143.6482387	5782	75.9042611	3133	89.258099	3624	120.7171333	4882	6.67E-05	-0.840828603	normal	0.024557391	-0.655218827	normal	0.976679101	-0.252315845	normal	0.004730135	-0.557847044	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00031|0|hsa:3417|IDH1, HEL-216, HEL-S-26, IDCD, IDH, IDP, IDPC, PICD; isocitrate dehydrogenase 1 (NADP+), soluble (EC:1.1.1.42); K00031 isocitrate dehydrogenase [EC:1.1.1.42] (A)"	Citrate cycle (TCA cycle) (ko00020);; Glutathione metabolism (ko00480);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230);; Peroxisome (ko04146);; Central carbon metabolism in cancer (ko05230)	[C]	Energy production and conversion	Isocitrate/isopropylmalate dehydrogenase	Isocitrate dehydrogenase [NADP] cytoplasmic GN=IDH1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	Isocitrate dehydrogenase [NADP] cytoplasmic [Pteropus alecto]
ENSG00000138430(OLA1)	--	93.60696389	2658	81.94149905	2431	91.70648054	2691	69.38495943	2035	63.75426897	1837	58.39963255	1687	0.724017096	-0.415868896	normal	0.699559218	-0.425319359	normal	0.008060726	-0.681485651	normal	0.00046356	-0.50659027	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTP binding (GO:0005525);; 	K06942|0|mcf:101926459|uncharacterized LOC101926459; K06942 (A)	--	[R]	General function prediction only	Protein of unknown function (DUF933);; 50S ribosome-binding GTPase;; Ferrous iron transport protein B	Obg-like ATPase 1 {ECO:0000255|HAMAP-Rule:MF_03167} OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: obg-like ATPase 1 [Ursus maritimus]
ENSG00000138433(CIR1)	--	6.783561445	314	7.094313566	325	6.851867	311	6.619072231	288	6.447436015	297	5.398356076	249	0.955974155	-0.154737071	normal	0.955794516	-0.150669632	normal	0.879026274	-0.327277899	normal	0.484059674	-0.209497705	normal	--	--	--	"K06066|1.1261e-134|hgl:101713751|Cir1; corepressor interacting with RBPJ, 1; K06066 CBF1 interacting corepressor (A)"	Notch signaling pathway (ko04330)	[K]	Transcription	N-terminal domain of CBF1 interacting co-repressor CIR	Corepressor interacting with RBPJ 1 GN=CIR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: corepressor interacting with RBPJ 1 isoform X2 [Camelus dromedarius]
ENSG00000138434(SSFA2)	--	20.04273331	1881	18.04837296	1703	19.62605583	1831	25.23283213	2386	26.43672111	2396	19.05615161	1713	0.918588964	0.312035194	normal	0.512678468	0.470768914	normal	0.982410712	-0.104308992	normal	0.336096483	0.240372554	normal	--	--	Molecular Function: receptor binding (GO:0005102);; 	--	--	--	--	Sperm-specific antigen 2 C-terminus;; Ki-ras-induced actin-interacting protein-IP3R-interacting domain	Sperm-specific antigen 2 GN=SSFA2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: sperm-specific antigen 2 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000138435(CHRNA1)	--	0	0	0.089609346	2	0	0	0	0	0	0	0.039844638	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04803|0|pon:100449821|CHRNA1; cholinergic receptor, nicotinic, alpha 1 (muscle); K04803 nicotinic acetylcholine receptor alpha-1 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Acetylcholine receptor subunit alpha (Precursor) GN=CHRNA1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: acetylcholine receptor subunit alpha isoform X1 [Orycteropus afer afer]
ENSG00000138439(FAM117B)	--	3.22229	294	3.38903	309	2.45189	221	1.60518	147	2.61195	238	1.61759	148	0.000168801	-1.023111593	down	0.794855395	-0.395857424	normal	0.424710901	-0.581842281	normal	0.06100179	-0.649958549	normal	--	--	--	--	--	--	--	Protein Family FAM117	Protein FAM117B GN=FAM117B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM117B [Odobenus rosmarus divergens]
ENSG00000138442(WDR12)	--	15.403636	1008	16.149429	1100	17.224379	1074	9.757601	655	8.618614	708	8.671184	603	0.023592354	-0.651518688	normal	0.024162549	-0.655975027	normal	0.000193165	-0.839455678	normal	2.28E-06	-0.71602201	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14863|0|ptr:459888|WDR12; WD repeat domain 12; K14863 ribosome biogenesis protein YTM1 (A)	--	[Z]	Cytoskeleton	"WD domain, G-beta repeat;; NLE (NUC135) domain"	Ribosome biogenesis protein WDR12 {ECO:0000255|HAMAP-Rule:MF_03029} OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: ribosome biogenesis protein WDR12 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000138443(ABI2)	--	30.68740905	2111	24.68297771	1746	31.20472926	2095	19.30478902	1350	15.10571259	1077	14.2252883	1095	0.009484509	-0.675179328	normal	0.004300904	-0.71766225	normal	2.80E-06	-0.94335204	normal	1.43E-07	-0.778700918	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05751|0|ptr:459892|ABI2; abl-interactor 2; K05751 abl interactor 2 (A)	Regulation of actin cytoskeleton (ko04810)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Abl-interactor HHR;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Abl interactor 2 GN=ABI2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: abl interactor 2 isoform X3 [Erinaceus europaeus]
ENSG00000138448(ITGAV)	--	101.8738551	10302	106.8214886	10883	99.97231311	9940	91.73151165	9429	86.29708542	8690	66.02742811	6688	0.993588869	-0.158555302	normal	0.955436697	-0.346020843	normal	0.160700336	-0.579854171	normal	0.045283477	-0.349610594	normal	--	--	--	"K06487|0|ptr:459807|ITGAV; integrin, alpha V; K06487 integrin alpha V (A)"	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Regulation of actin cytoskeleton (ko04810);; Thyroid hormone signaling pathway (ko04919);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Small cell lung cancer (ko05222);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella;; Integrin alpha cytoplasmic region"	Integrin alpha-V light chain (Precursor) GN=ITGAV OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin alpha-V [Balaenoptera acutorostrata scammoni]
ENSG00000138449(SLC40A1)	--	5.146786153	281	6.608633605	361	5.335745742	287	4.029973562	221	5.211031716	283	4.50718773	243	0.832974168	-0.375037299	normal	0.820052424	-0.370863855	normal	0.930912343	-0.246969866	normal	0.205203664	-0.335633758	normal	--	--	Molecular Function: iron ion transmembrane transporter activity (GO:0005381);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: iron ion transmembrane transport (GO:0034755);; 	"K14685|0|pps:100993297|SLC40A1; solute carrier family 40 (iron-regulated transporter), member 1; K14685 solute carrier family 40 (iron-regulated transporter), member 1 (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Ferroportin1 (FPN1)	Solute carrier family 40 member 1 GN=SLC40A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 40 member 1 isoform X2 [Canis lupus familiaris]
ENSG00000138459(SLC35A5)	--	10.20062328	482	8.297738995	400	11.1906019	430	11.52045996	466	10.84768487	462	11.153233	503	0.96831414	-0.079278418	normal	0.950043327	0.18581219	normal	0.941526486	0.217223279	normal	0.728258727	0.104279243	normal	--	--	Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15274|0|hsa:55032|SLC35A5; solute carrier family 35, member A5; K15274 solute carrier family 35 (probable UDP-sugar transporter), member A5 (A)"	--	[G]	Carbohydrate transport and metabolism	Nucleotide-sugar transporter;; UAA transporter family;; EamA-like transporter family;; Triose-phosphate Transporter family	Probable UDP-sugar transporter protein SLC35A5 GN=SLC35A5 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: probable UDP-sugar transporter protein SLC35A5 isoform X4 [Equus przewalskii]
ENSG00000138463(DIRC2)	--	9.921244	829	8.871728	773	9.294003	757	8.300884	879	8.488687	922	11.666995	1049	0.976554203	0.053562392	normal	0.943451094	0.232454932	normal	0.49705355	0.461571371	normal	0.182243311	0.252041422	normal	--	--	--	"K15381|0|hsa:84925|DIRC2, RCC4; disrupted in renal carcinoma 2; K15381 MFS transporter, FLVCR family, disrupted in renal carcinoma protein 2 (A)"	--	[R]	General function prediction only	--	Disrupted in renal carcinoma protein 2 GN=DIRC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: disrupted in renal carcinoma protein 2 [Oryctolagus cuniculus]
ENSG00000138468(SENP7)	--	2.913202007	218	3.260201578	217	3.837562266	248	3.140866	233	2.535621631	182	3.265437	220	0.96533368	0.064728264	normal	0.924376361	-0.27310187	normal	0.951740933	-0.179962147	normal	0.749754128	-0.12636519	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	K08596|0|pps:100985684|SENP7; SUMO1/sentrin specific peptidase 7; K08596 sentrin-specific protease 7 [EC:3.4.22.68] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ulp1 protease family, C-terminal catalytic domain"	Sentrin-specific protease 7 GN=SENP7 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sentrin-specific protease 7 isoform X1 [Galeopterus variegatus]
ENSG00000138495(COX17)	--	66.72992	422	77.294079	480	49.326455	388	60.505507	471	47.954641	377	67.87777	459	0.962596907	0.127213258	normal	0.808161406	-0.368582586	normal	0.934499936	0.233309078	normal	1	-0.002771676	normal	--	--	--	K02260|2.62979e-31|ptr:100609675|COX17; cytochrome c oxidase copper chaperone; K02260 cytochrome c oxidase assembly protein subunit 17 (A)	Oxidative phosphorylation (ko00190)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cytochrome C oxidase copper chaperone (COX17)	Cytochrome c oxidase copper chaperone GN=COX17 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	Cytochrome c oxidase copper chaperone [Bos mutus]
ENSG00000138496(PARP9)	--	3.634185	265	3.811291972	271	4.097775926	275	7.75873476	532	6.798446942	473	7.789556326	541	4.00E-05	0.970554911	normal	0.006284548	0.778791196	normal	4.28E-05	0.964055008	normal	1.27E-06	0.909615649	normal	[R]	General function prediction only	--	"K15260|0|hsa:83666|PARP9, ARTD9, BAL, BAL1, MGC:7868; poly (ADP-ribose) polymerase family, member 9 (EC:2.4.2.30); K15260 poly [ADP-ribose] polymerase 9 [EC:2.4.2.30] (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	Macro domain;; Poly(ADP-ribose) polymerase catalytic domain	Poly [ADP-ribose] polymerase 9 GN=PARP9 OS=Homo sapiens (Human) PE=1 SV=2	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: poly [ADP-ribose] polymerase 9 [Galeopterus variegatus]
ENSG00000138587(MNS1)	--	3.70549	176	3.54316	169	4.44974	209	2.93348	141	2.54384	120	2.12673	101	0.897364399	-0.347316978	normal	0.710978676	-0.509971704	normal	0.000788671	-1.046308093	down	0.038040673	-0.635736489	normal	--	--	--	--	--	--	--	"Tumour suppressor, Mitostatin"	Meiosis-specific nuclear structural protein 1 GN=MNS1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: meiosis-specific nuclear structural protein 1 [Galeopterus variegatus]
ENSG00000138592(USP8)	--	23.43107237	1825	23.93129447	1881	23.57134546	1871	23.95417052	1914	26.60640757	1926	24.94187401	1863	0.98585214	0.037831002	normal	0.986021445	0.012671229	normal	0.986192724	-0.014461612	normal	0.974731668	0.010986041	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11839|0|hsa:9101|USP8, HumORF8, SPG59, UBPY; ubiquitin specific peptidase 8 (EC:3.4.19.12); K11839 ubiquitin carboxyl-terminal hydrolase 8 [EC:3.4.19.12] (A)"	Endocytosis (ko04144)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; USP8 dimerisation domain;; Ubiquitin carboxyl-terminal hydrolase;; Rhodanese-like domain	Ubiquitin carboxyl-terminal hydrolase 8 GN=USP8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 8 isoform X1 [Leptonychotes weddellii]
ENSG00000138593(SECISBP2L)	--	6.672060767	864	7.48137901	959	6.82656	868	6.750246036	861	6.163714	802	6.583467	814	0.977322537	-0.035786589	normal	0.917957091	-0.27887351	normal	0.97328168	-0.100776344	normal	0.532669515	-0.141037447	normal	--	--	--	--	--	--	--	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	Selenocysteine insertion sequence-binding protein 2-like GN=SECISBP2L OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	selenocysteine insertion sequence-binding protein 2-like [Sus scrofa]
ENSG00000138594(TMOD3)	--	43.90583346	4401	55.571786	5302	50.909103	4506	41.67745	4199	37.161697	3630	36.96111786	3514	0.990965829	-0.098582607	normal	0.171974952	-0.567796691	normal	0.88682905	-0.366884755	normal	0.031603964	-0.3469413	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: tropomyosin binding (GO:0005523);; Biological Process: pointed-end actin filament capping (GO:0051694);; 	"K10370|0|hsa:29766|TMOD3, UTMOD; tropomodulin 3 (ubiquitous); K10370 tropomodulin (A)"	--	[Z]	Cytoskeleton	Tropomodulin	Tropomodulin-3 GN=TMOD3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tropomodulin-3 [Trichechus manatus latirostris]
ENSG00000138600(SPPL2A)	--	51.46052291	2107	51.47412065	2355	46.62991954	2020	40.70143002	1948	42.42192555	1826	47.42843064	2167	0.98050722	-0.143919712	normal	0.804857452	-0.388182915	normal	0.984945705	0.092985196	normal	0.464720966	-0.146836947	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09596|0|hsa:84888|SPPL2A, IMP3, PSL2; signal peptide peptidase like 2A (EC:3.4.23.-); K09596 signal peptide peptidase-like 2A [EC:3.4.23.-] (A)"	--	[R]	General function prediction only	Signal peptide peptidase;; PA domain	Signal peptide peptidase-like 2A (Precursor) GN=SPPL2A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: signal peptide peptidase-like 2A [Leptonychotes weddellii]
ENSG00000138604(GLCE)	--	14.99529842	955	11.21698907	785	11.96162	790	10.318476	710	11.2002468	748	10.196598	670	0.512439386	-0.45765648	normal	0.972364351	-0.090901518	normal	0.934490432	-0.245472133	normal	0.156034004	-0.271082869	normal	--	--	"Biological Process: glycosaminoglycan biosynthetic process (GO:0006024);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: racemase and epimerase activity, acting on carbohydrates and derivatives (GO:0016857);; "	"K01793|0|hsa:26035|GLCE, HSEPI; glucuronic acid epimerase (EC:5.1.3.17); K01793 heparosan-N-sulfate-glucuronate 5-epimerase [EC:5.1.3.17] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[G]	Carbohydrate transport and metabolism	D-glucuronyl C5-epimerase C-terminus	D-glucuronyl C5-epimerase GN=GLCE OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: D-glucuronyl C5-epimerase isoform X1 [Canis lupus familiaris] 
ENSG00000138606(SHF)	--	1.353540315	56	1.778458519	43	1.05668542	36	0.813235608	26	1.196994922	42	0.264944014	11	0.321506305	-1.092693455	normal	0.979518348	-0.053471026	normal	0.163889806	-1.591640908	normal	0.215037552	-0.795992512	normal	--	--	--	--	--	--	--	SH2 domain	SH2 domain-containing adapter protein F OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"SH2 domain-containing adapter protein F, partial [Bos mutus]"
ENSG00000138613(APH1B)	--	14.04178586	671	12.97771381	648	10.19102581	606	11.3305664	535	9.958307641	524	12.15019581	572	0.816379789	-0.356689159	normal	0.864147192	-0.327003105	normal	0.969745669	-0.091359383	normal	0.214904952	-0.260246983	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein processing (GO:0016485);; Biological Process: positive regulation of catalytic activity (GO:0043085);; 	K06172|3.38935e-160|ptr:467700|APH1B; APH1B gamma secretase subunit; K06172 anterior pharynx defective 1 (A)	Notch signaling pathway (ko04330);; Alzheimer's disease (ko05010)	[S]	Function unknown	Aph-1 protein	Gamma-secretase subunit APH-1B GN=APH1B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: gamma-secretase subunit APH-1B isoform X1 [Leptonychotes weddellii] 
ENSG00000138614(INTS14)	--	26.99140488	1024	30.55450364	1150	26.77218889	969	31.834073	1235	38.141275	1392	34.98899672	1363	0.946458481	0.239135978	normal	0.942882722	0.253795055	normal	0.402963106	0.483286614	normal	0.051031102	0.323163944	normal	--	--	--	--	--	--	--	von Willebrand factor type A domain	von Willebrand factor A domain-containing protein 9 GN=VWA9 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	UPF0464 protein like protein [Myotis brandtii]
ENSG00000138615(CILP)	--	0.017183	2	0.0338788	4	0.0167821	1	0	0	0.00837622	0	0.0255946	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Mucin-2 protein WxxW repeating region;; Domain of unknown function (DUF4480);; Carboxypeptidase regulatory-like domain;; Immunoglobulin domain;; Thrombospondin type 1 domain;; Immunoglobulin I-set domain	Cartilage intermediate layer protein 1 C2 (Precursor) GN=CILP OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: cartilage intermediate layer protein 1 [Panthera tigris altaica]
ENSG00000138617(PARP16)	--	6.020317796	268	4.95381865	221	5.382919273	237	6.154119001	277	6.834550396	299	5.891751168	265	0.967285431	0.016726393	normal	0.773211345	0.412239137	normal	0.956567448	0.151896825	normal	0.557156575	0.190855896	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K00774|0|hsa:54956|PARP16, ARTD15, C15orf30, pART15; poly (ADP-ribose) polymerase family, member 16 (EC:2.4.2.31); K00774 poly [ADP-ribose] polymerase 16 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain	Mono [ADP-ribose] polymerase PARP16 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mono [ADP-ribose] polymerase PARP16 [Orycteropus afer afer]
ENSG00000138621(PPCDC)	--	12.51463547	248	16.30400168	311	14.99546125	303	9.094502949	224	11.95181895	185	15.17437664	324	0.952311794	-0.176522262	normal	0.022911903	-0.765930081	normal	0.964643375	0.087959966	normal	0.553641043	-0.253890019	normal	[H]	Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; 	K01598|1.3604e-133|ggo:101141249|PPCDC; phosphopantothenoylcysteine decarboxylase; K01598 phosphopantothenoylcysteine decarboxylase [EC:4.1.1.36] (A)	Pantothenate and CoA biosynthesis (ko00770)	[PD]	"Inorganic ion transport and metabolism;; Cell cycle control, cell division, chromosome partitioning"	Flavoprotein	Phosphopantothenoylcysteine decarboxylase GN=PPCDC OS=Homo sapiens (Human) PE=1 SV=2	DP	"Cell cycle control, cell division, chromosome partitioning;; Inorganic ion transport and metabolism"	PREDICTED: phosphopantothenoylcysteine decarboxylase [Ceratotherium simum simum]
ENSG00000138622(HCN4)	--	0.175654812	24	0.09347839	13	0.167590179	23	0.08741249	12	0.098590209	13	0.114755925	16	0.939249162	-0.943862785	normal	--	--	--	0.980960715	-0.492815241	normal	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04957|0|hsa:10021|HCN4, SSS2; hyperpolarization activated cyclic nucleotide-gated potassium channel 4; K04957 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 (A)"	cAMP signaling pathway (ko04024)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein N-terminal;; Cyclic nucleotide-binding domain;; Ion transport protein	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 GN=HCN4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 [Orycteropus afer afer]
ENSG00000138623(SEMA7A)	--	0.265125837	16	0.27819608	20	0.467082867	26	1.521798652	95	2.0214009	106	0.332624245	22	3.73E-09	2.431479393	up	2.87E-09	2.300746006	up	0.985025235	-0.234458102	normal	0.117468711	1.823486118	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06529|0|pon:100451776|SEMA7A; semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group); K06529 semaphorin 7 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat;; Immunoglobulin domain	Semaphorin-7A (Precursor) GN=SEMA7A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-7A isoform X1 [Galeopterus variegatus]
ENSG00000138629(UBL7)	--	21.4443759	479	22.1217651	511	22.04860247	513	18.9028555	395	17.76147429	403	19.56873435	452	0.884597073	-0.307915605	normal	0.815561161	-0.36275796	normal	0.950575349	-0.190329324	normal	0.201405885	-0.286657135	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; UBA/TS-N domain	Ubiquitin-like protein 7 GN=UBL7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like protein 7 [Orycteropus afer afer] 
ENSG00000138639(ARHGAP24)	--	3.34997783	220	3.664118865	193	3.7724204	169	4.114917562	231	3.467594395	198	4.0727979	197	0.966390695	0.039289288	normal	0.965753058	0.015354245	normal	0.947491251	0.211129511	normal	0.855582019	0.083106124	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; PH domain	Rho GTPase-activating protein 24 GN=ARHGAP24 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 24 isoform X1 [Orycteropus afer afer]
ENSG00000138640(FAM13A)	--	5.140009421	407	5.62257885	508	4.728587503	417	4.492682143	432	4.321396037	372	4.243554183	432	0.968726609	0.054968833	normal	0.543537011	-0.469312617	normal	0.969495322	0.042540905	normal	0.657499515	-0.129383361	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	RhoGAP domain	Protein FAM13A GN=FAM13A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein FAM13A isoform X4 [Ursus maritimus]
ENSG00000138641(HERC3)	--	1.474475006	118	2.205609795	100	1.531821857	113	4.576900072	319	3.961566758	316	3.226343465	264	1.69E-08	1.392477382	up	5.11E-11	1.623942105	up	7.39E-06	1.20506313	up	1.74E-09	1.419884249	up	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	K10614|0|ptr:461371|HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3; K10614 E3 ubiquitin-protein ligase HERC3 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Regulator of chromosome condensation (RCC1) repeat;; HECT-domain (ubiquitin-transferase);; Regulator of chromosome condensation (RCC1) repeat	Probable E3 ubiquitin-protein ligase HERC3 GN=HERC3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase HERC3 [Tupaia chinensis]
ENSG00000138642(HERC6)	--	2.077057312	151	2.738373852	196	2.617249813	189	3.253432402	237	3.344865401	242	3.653526701	266	0.30687563	0.614477922	normal	0.91832876	0.280774161	normal	0.643013604	0.48148601	normal	0.106796228	0.454262993	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat	Probable E3 ubiquitin-protein ligase HERC6 GN=HERC6 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase HERC6 [Trichechus manatus latirostris]
ENSG00000138646(HERC5)	--	5.376722	349	4.838885	316	5.203161294	338	3.070641912	203	3.7022	221	4.201804571	276	0.006642566	-0.80785531	normal	0.43751235	-0.534230135	normal	0.899061428	-0.29916252	normal	0.019884918	-0.539112998	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat	E3 ISG15--protein ligase HERC5 GN=HERC5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ISG15--protein ligase HERC5 isoform X1 [Camelus bactrianus]
ENSG00000138650(PCDH10)	--	0.083914633	7	0.1100892	10	0.02342724	2	0.397574	40	0.730405	75	0.3419936	34	0.002209654	2.255180947	up	1.32E-08	2.712709812	up	5.09E-05	3.331506258	up	0.001076041	2.948133276	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K16499|0|ptr:461488|PCDH10; protocadherin 10; K16499 protocadherin delta 2 (A)	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin-10 (Precursor) GN=PCDH10 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protocadherin-10-like isoform 3 [Ceratotherium simum simum]
ENSG00000138653(NDST4)	--	0.016837325	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Molecular Function: [heparan sulfate]-glucosamine N-sulfotransferase activity (GO:0015016);; Molecular Function: hydrolase activity (GO:0016787);; 	"K02579|0|hsa:64579|NDST4, NDST-4, NHSST4; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4 (EC:2.8.2.8); K02579 heparan sulfate N-deacetylase/N-sulfotransferase NDST4 [EC:3.1.1.- 2.8.2.-] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	heparan sulfate-N-deacetylase;; Sulfotransferase domain	Heparan sulfate N-sulfotransferase 4 GN=NDST4 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 4 [Camelus bactrianus]
ENSG00000138658(ZGRF1)	--	2.515263073	233	2.989419456	190	1.926658355	237	1.960062222	189	1.881011866	177	2.203860143	230	0.890630994	-0.330352062	normal	0.960128427	-0.122664779	normal	0.966022697	-0.051212901	normal	0.655552492	-0.167540722	normal	[L]	"Replication, recombination and repair"	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[A]	RNA processing and modification	AAA domain;; AAA domain;; Protein of unknown function (DUF2439);; GRF zinc finger;; Viral (Superfamily 1) RNA helicase	Protein ZGRF1 GN=ZGRF1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein ZGRF1 [Galeopterus variegatus]
ENSG00000138660(AP1AR)	--	10.061288	422	10.557703	443	10.886797	450	11.402108	482	11.22290719	472	12.53582302	528	0.957009226	0.160411144	normal	0.967920939	0.069822668	normal	0.940209143	0.221633196	normal	0.57654586	0.151610727	normal	--	--	"Biological Process: regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315);; Molecular Function: AP-1 adaptor complex binding (GO:0035650);; Biological Process: vesicle targeting, trans-Golgi to endosome (GO:0048203);; Biological Process: negative regulation of substrate adhesion-dependent cell spreading (GO:1900025);; Biological Process: negative regulation of cell motility (GO:2000146);; "	--	--	--	--	--	AP-1 complex-associated regulatory protein GN=AP1AR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: AP-1 complex-associated regulatory protein isoform X3 [Canis lupus familiaris]
ENSG00000138663(COPS4)	--	12.62814974	378	13.36030442	399	12.92691577	382	14.96849546	450	14.76944813	443	12.12196976	364	0.939591529	0.219886588	normal	0.9610905	0.129027135	normal	0.966507034	-0.077610837	normal	0.766111774	0.095293491	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12178|0|umr:103665367|COPS4; COP9 signalosome subunit 4; K12178 COP9 signalosome complex subunit 4 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PCI domain	COP9 signalosome complex subunit 4 GN=COPS4 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: COP9 signalosome complex subunit 4 isoform X1 [Felis catus] 
ENSG00000138668(HNRNPD)	--	119.7368443	3571	115.0639137	3525	123.321567	3712	143.5988374	4481	144.4847273	4176	127.1497469	3801	0.953690107	0.296546231	normal	0.97774212	0.22298392	normal	0.991646374	0.025880453	normal	0.335891629	0.183376244	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13044|2.58645e-144|bacu:103017017|HNRNPD; heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa); K13044 heterogeneous nuclear ribonucleoprotein A/B/D (A)"	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; CBFNT (NUC161) domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Heterogeneous nuclear ribonucleoprotein D0 GN=HNRNPD OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"PREDICTED: LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) [Balaenoptera acutorostrata scammoni]"
ENSG00000138669(PRKG2)	--	0.791716035	60	0.664105889	47	0.612601196	42	0.518316307	37	0.3620294	29	0.567422681	38	0.825342696	-0.705049932	normal	0.89340728	-0.689521498	normal	0.979830713	-0.147110174	normal	0.368937191	-0.540306655	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07376|0|ptr:461217|PRKG2; protein kinase, cGMP-dependent, type II; K07376 protein kinase, cGMP-dependent [EC:2.7.11.12] (A)"	cGMP-PKG signaling pathway (ko04022);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term depression (ko04730);; Olfactory transduction (ko04740);; Salivary secretion (ko04970)	[T]	Signal transduction mechanisms	Protein kinase domain;; Cyclic nucleotide-binding domain;; Protein tyrosine kinase	cGMP-dependent protein kinase 2 GN=PRKG2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cGMP-dependent protein kinase 2 isoform 1 [Equus caballus] 
ENSG00000138674(SEC31A)	--	38.67006373	2042	34.84213914	2061	36.96729461	1848	46.08733174	2520	48.44385501	2820	42.03636517	2480	0.949075704	0.27242382	normal	0.694694838	0.430652957	normal	0.717833736	0.415789187	normal	0.015588288	0.372680541	normal	[R]	General function prediction only	--	"K14005|0|ptr:461210|SEC31A, SEC31L1; SEC31 homolog A (S. cerevisiae); K14005 protein transport protein SEC31 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"WD domain, G-beta repeat;; Sec23-binding domain of Sec16"	Protein transport protein Sec31A GN=SEC31A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec31A isoform X20 [Canis lupus familiaris]
ENSG00000138675(FGF5)	--	0.259820179	20	0.384097502	28	0.49428615	33	0.5611655	44	0.487313694	39	0.488159784	39	0.64040778	1.051028312	normal	0.966700193	0.436566134	normal	0.979261258	0.223294419	normal	0.38177421	0.56983088	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|4.04983e-138|pps:100980043|FGF5; fibroblast growth factor 5; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 5 (Precursor) GN=FGF5 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 5 [Equus caballus]
ENSG00000138678(GPAT3)	--	22.3121733	971	20.61563267	905	19.2396755	830	15.68806363	686	14.99397144	647	10.67633562	463	0.226575205	-0.531089563	normal	0.348123205	-0.504576367	normal	0.000249726	-0.848291227	normal	0.000628174	-0.613836261	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	K13506|0|pon:100450687|AGPAT9; 1-acylglycerol-3-phosphate O-acyltransferase 9; K13506 glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] (A)	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	Glycerol-3-phosphate acyltransferase 3 GN=AGPAT9 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: glycerol-3-phosphate acyltransferase 3 isoform X2 [Oryctolagus cuniculus]
ENSG00000138685(FGF2)	--	21.20113437	1365	19.40237	1600	21.88797	1647	28.70198377	2466	26.69805	2117	23.40143267	1940	0.000142811	0.821742108	normal	0.810156997	0.382207835	normal	0.961753619	0.227731787	normal	0.002517794	0.478358909	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K18497|8.6188e-110|pps:100968351|FGF2; fibroblast growth factor 2 (basic); K18497 fibroblast growth factor 2 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 2 (Precursor) GN=FGF2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: fibroblast growth factor 2 [Ochotona princeps]
ENSG00000138686(BBS7)	--	5.451020018	314	6.177990061	341	5.383470016	305	5.607580101	330	5.09699095	279	5.78696066	314	0.967456132	0.040675058	normal	0.89023294	-0.309413276	normal	0.967561208	0.033500164	normal	0.835719276	-0.078260339	normal	--	--	--	K16749|0|pps:100986769|BBS7; Bardet-Biedl syndrome 7; K16749 Bardet-Biedl syndrome 7 protein (A)	--	--	--	--	Bardet-Biedl syndrome 7 protein GN=BBS7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Bardet-Biedl syndrome 7 protein isoform X1 [Mustela putorius furo] 
ENSG00000138688(KIAA1109)	--	6.475494286	1642	7.57856555	1540	5.739327421	1437	7.000275741	1558	6.80174791	1460	6.495148598	1437	0.981008085	-0.106488843	normal	0.980474069	-0.098289393	normal	0.983609949	-0.008282725	normal	0.762208716	-0.07376633	normal	--	--	--	--	--	[S]	Function unknown	Fragile site-associated protein C-terminus	Uncharacterized protein KIAA1109 GN=KIAA1109 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein KIAA1109 homolog [Panthera tigris altaica]
ENSG00000138696(BMPR1B)	--	5.651329634	394	6.306487126	503	4.451359589	324	5.8707931	490	9.234664801	767	8.486153268	711	0.905906587	0.282763539	normal	0.121554277	0.585805554	normal	1.30E-07	1.121939506	up	0.067643564	0.668034167	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K13578|0|pps:100991587|BMPR1B; bone morphogenetic protein receptor, type IB; K13578 bone morphogenetic protein receptor type-1B [EC:2.7.11.30] (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Transforming growth factor beta type I GS-motif;; Activin types I and II receptor domain	Bone morphogenetic protein receptor type-1B (Precursor) GN=BMPR1B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein receptor type-1B isoform X1 [Bubalus bubalis]
ENSG00000138698(RAP1GDS1)	--	12.56213315	573	11.91532412	626	14.98091945	679	17.39233705	909	17.3336865	853	14.11974936	681	0.038936496	0.633553295	normal	0.656042014	0.424075747	normal	0.975152984	-0.004039235	normal	0.060173328	0.357661469	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Armadillo/beta-catenin-like repeat;; HEAT repeats;; V-ATPase subunit H	Rap1 GTPase-GDP dissociation stimulator 1 GN=RAP1GDS1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rap1 GTPase-GDP dissociation stimulator 1 isoform X1 [Ursus maritimus] 
ENSG00000138709(LARP1B)	--	4.730665663	272	4.314238154	235	5.59500452	304	5.514132881	328	5.09022563	290	4.712345328	259	0.93305905	0.238031136	normal	0.913980142	0.280339075	normal	0.933744198	-0.238125838	normal	0.809923589	0.091326099	normal	[OJ]	"Posttranslational modification, protein turnover, chaperones;; Translation, ribosomal structure and biogenesis"	--	"K18757|0|pps:100986595|LARP1B; La ribonucleoprotein domain family, member 1B; K18757 la-related protein 1 (A)"	--	[OJ]	"Posttranslational modification, protein turnover, chaperones;; Translation, ribosomal structure and biogenesis"	La domain	La-related protein 1B GN=LARP1B OS=Homo sapiens (Human) PE=1 SV=2	JO	"Translation, ribosomal structure and biogenesis;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: la-related protein 1B isoform X1 [Leptonychotes weddellii]
ENSG00000138735(PDE5A)	--	1.021191	116	1.05873166	120	1.361872238	111	1.344327864	123	1.290038501	130	0.83171585	95	0.968700846	0.053019256	normal	0.965191876	0.092925355	normal	0.955859163	-0.229468787	normal	0.985893701	-0.01779607	normal	[T]	Signal transduction mechanisms	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; "	"K13762|0|hsa:8654|PDE5A, CGB-PDE, CN5A, PDE5; phosphodiesterase 5A, cGMP-specific (EC:3.1.4.35); K13762 cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; GAF domain;; GAF domain;; GAF domain	"cGMP-specific 3',5'-cyclic phosphodiesterase GN=PDE5A OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: cGMP-specific 3',5'-cyclic phosphodiesterase isoform X1 [Oryctolagus cuniculus] "
ENSG00000138738(PRDM5)	--	2.967193099	207	4.503375872	303	3.827734869	268	3.050056381	246	3.63461562	219	3.450943969	261	0.943147116	0.216718377	normal	0.594814829	-0.486941274	normal	0.966478743	-0.046210393	normal	0.746231109	-0.120854727	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger;; Drought induced 19 protein (Di19), zinc-binding"	PR domain zinc finger protein 5 GN=PRDM5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: PR domain zinc finger protein 5 isoform X1 [Galeopterus variegatus]
ENSG00000138741(TRPC3)	--	0.120275844	7	0.049733663	2	0.034004426	1	0	0	0.181985347	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04966|0|hsa:7222|TRPC3, TRP3; transient receptor potential cation channel, subfamily C, member 3; K04966 transient receptor potential cation channel subfamily C member 3 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Transient receptor ion channel II;; Ankyrin repeats (3 copies);; Polycystin cation channel;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Short transient receptor potential channel 3 GN=TRPC3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: short transient receptor potential channel 3 isoform X1 [Sus scrofa]
ENSG00000138744(NAAA)	--	17.075996	558	14.45795397	473	16.08807078	514	14.289144	455	15.69968957	470	11.356857	372	0.865581757	-0.3242401	normal	0.970038174	-0.030508133	normal	0.517546282	-0.473113605	normal	0.223499107	-0.274105155	normal	--	--	--	"K13720|0|ptr:739402|NAAA, ASAHL; N-acylethanolamine acid amidase; K13720 N-acylethanolamine-hydrolysing acid amidase [EC:3.5.1.-] (A)"	--	--	--	"beta subunit of N-acylethanolamine-hydrolyzing acid amidase;; Linear amide C-N hydrolases, choloylglycine hydrolase family"	N-acylethanolamine-hydrolyzing acid amidase subunit beta (Precursor) GN=NAAA OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	"PREDICTED: N-acylethanolamine-hydrolyzing acid amidase, partial [Galeopterus variegatus]"
ENSG00000138750(NUP54)	--	12.25368728	495	11.60061536	462	12.01300838	473	12.63470506	501	13.54563594	534	10.46781877	414	0.9716147	-0.013408817	normal	0.951094465	0.186950742	normal	0.947071815	-0.199817446	normal	1	-0.002619863	normal	--	--	--	K14308|0|ptr:461240|NUP54; nucleoporin 54kDa; K14308 nuclear pore complex protein Nup54 (A)	RNA transport (ko03013)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Nucleoporin complex subunit 54	Nucleoporin p54 GN=NUP54 OS=Homo sapiens (Human) PE=1 SV=2	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nucleoporin p54 isoform X1 [Equus przewalskii]
ENSG00000138756(BMP2K)	--	4.080418146	280	4.452216103	310	4.221822468	286	4.8928303	353	4.822425451	352	4.973098906	359	0.895966933	0.301930885	normal	0.954098462	0.16114257	normal	0.882032765	0.318172572	normal	0.338595519	0.259280164	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08854|0|pps:100983883|BMP2K; BMP2 inducible kinase; K08854 BMP2 inducible kinase [EC:2.7.11.1] (A)	Transcriptional misregulation in cancer (ko05202)	--	--	BMP-2-inducible protein kinase C-terminus;; Protein kinase domain;; Protein tyrosine kinase	BMP-2-inducible protein kinase GN=BMP2K OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: BMP-2-inducible protein kinase [Galeopterus variegatus]
ENSG00000138757(G3BP2)	--	61.28346825	3676	74.44327037	3884	64.69666323	3704	69.20242967	3949	63.63197097	3657	65.87683401	3695	0.990945095	0.072489104	normal	0.989324018	-0.108265679	normal	0.99163951	-0.011796354	normal	0.959389613	-0.016729065	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	--	--	[T]	Signal transduction mechanisms	"Nuclear transport factor 2 (NTF2) domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Ras GTPase-activating protein-binding protein 2 GN=G3BP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating protein-binding protein 2 isoform X1 [Oryctolagus cuniculus] 
ENSG00000138758(SEPT11)	--	20.41233951	1945	19.22430815	1822	21.34140918	2001	21.04144183	2014	19.95697896	1884	18.60710973	1686	0.986681556	0.019446169	normal	0.985609566	0.02682755	normal	0.951680772	-0.255197684	normal	0.781587836	-0.068363435	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K16939|0|ptr:461233|SEPT11; septin 11; K16939 septin 6/8/11 (A)	Bacterial invasion of epithelial cells (ko05100)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Septin;; 50S ribosome-binding GTPase	Septin-11 GN=SEPT11 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: septin-11 [Ovis aries]
ENSG00000138759(FRAS1)	--	4.808477529	1559	3.778322704	1177	4.019348026	1298	6.732085	2203	8.126354173	2693	7.479789231	2363	0.493504404	0.467626926	normal	5.99E-10	1.171650565	up	4.99E-05	0.855288397	normal	2.84E-07	0.826627977	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell communication (GO:0007154);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Calx-beta domain;; von Willebrand factor type C domain;; Growth factor receptor domain IV	Extracellular matrix protein FRAS1 (Precursor) GN=FRAS1 OS=Homo sapiens (Human) PE=1 SV=2	OPT	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism;; Signal transduction mechanisms"	PREDICTED: extracellular matrix protein FRAS1 [Equus caballus]
ENSG00000138760(SCARB2)	--	44.87181517	3305	44.108824	3353	42.36059598	3032	40.68252889	2953	37.3948716	2733	43.36018902	3196	0.979910945	-0.19320609	normal	0.932171621	-0.316235287	normal	0.98957003	0.067673333	normal	0.467548188	-0.146770963	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K12384|0|ptr:461239|SCARB2; scavenger receptor class B, member 2; K12384 lysosome membrane protein 2 (A)"	Lysosome (ko04142)	[T]	Signal transduction mechanisms	CD36 family	Lysosome membrane protein 2 GN=SCARB2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: lysosome membrane protein 2 [Tupaia chinensis]
ENSG00000138764(CCNG2)	--	7.2135282	287	13.541967	516	9.58322128	369	6.4026741	255	8.81020456	342	19.50113549	747	0.946130409	-0.200247584	normal	0.110796322	-0.612579497	normal	3.84E-06	1.006238464	up	0.891661594	0.179279602	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	K10146|0|ptr:461229|CCNG2; cyclin G2; K10146 cyclin G2 (A)	FoxO signaling pathway (ko04068);; p53 signaling pathway (ko04115)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-G2 GN=CCNG2 OS=Homo sapiens (Human) PE=2 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-G2 isoform X1 [Chrysochloris asiatica]
ENSG00000138767(CNOT6L)	--	7.085751849	533	6.166898434	577	9.201420098	599	7.901118329	739	7.736376524	625	6.467268212	558	0.59608372	0.439526429	normal	0.969054881	0.093622509	normal	0.967619628	-0.110293748	normal	0.54866009	0.147511623	normal	[A]	RNA processing and modification	Molecular Function: protein binding (GO:0005515);; 	"K12603|0|ptr:467690|CNOT6L; CCR4-NOT transcription complex, subunit 6-like; K12603 CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4] (A)"	RNA degradation (ko03018)	[K]	Transcription	Endonuclease/Exonuclease/phosphatase family;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat	CCR4-NOT transcription complex subunit 6-like GN=CNOT6L OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 6-like [Bubalus bubalis]
ENSG00000138768(USO1)	--	33.851425	2591	29.849397	2269	33.124935	2484	31.20377	2407	28.123695	2148	31.94798	2447	0.983744987	-0.137020808	normal	0.984763121	-0.100420372	normal	0.988500978	-0.029924159	normal	0.69230661	-0.089923608	normal	--	--	Cellular Component: Golgi membrane (GO:0000139);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: protein transporter activity (GO:0008565);; Cellular Component: membrane (GO:0016020);; Biological Process: vesicle fusion with Golgi apparatus (GO:0048280);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Uso1 / p115 like vesicle tethering protein, head region;; Uso1 / p115 like vesicle tethering protein, C terminal region"	General vesicular transport factor p115 GN=USO1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: general vesicular transport factor p115 isoform X2 [Lipotes vexillifer]
ENSG00000138769(CDKL2)	--	1.382981385	94	1.720307764	116	1.91692645	124	1.017614813	68	0.666341751	46	1.074220911	78	0.878048717	-0.488525422	normal	0.000577241	-1.327386728	down	0.515618056	-0.666741513	normal	0.031105838	-0.819394964	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08824|0|mcf:101926402|CDKL2; Cyclin-dependent kinase-like 2 (EC:2.7.11.22); K08824 cyclin-dependent kinase-like [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase-like 2 GN=CDKL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-dependent kinase-like 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000138771(SHROOM3)	--	2.884123	595	2.524827013	518	2.7336229	563	4.59833	937	4.172133	863	5.107449	1057	0.047056795	0.623035136	normal	0.008671499	0.713351963	normal	3.64E-05	0.898686713	normal	1.50E-06	0.748659021	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: actin filament binding (GO:0051015);; 	"K18625|0|hsa:57619|SHROOM3, APXL3, SHRM, ShrmL; shroom family member 3; K18625 protein Shroom (A)"	Tight junction (ko04530)	--	--	Apx/Shroom domain ASD2;; Apx/Shroom domain ASD1;; PDZ domain (Also known as DHR or GLGF)	Protein Shroom3 GN=SHROOM3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein Shroom3 [Ceratotherium simum simum]
ENSG00000138772(ANXA3)	--	36.18453507	1161	37.64756934	1240	40.62664818	1327	63.27429094	2069	50.83988075	1623	53.24573727	1726	0.000287714	0.801928183	normal	0.826828562	0.36650458	normal	0.81498173	0.370601307	normal	0.000681545	0.517686699	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	"K17089|0|hsa:306|ANXA3, ANX3; annexin A3 (EC:3.1.4.43); K17089 annexin A3 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A3 GN=ANXA3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A3 [Equus caballus] 
ENSG00000138777(PPA2)	--	29.18974911	704	22.749575	571	25.06669937	597	40.4622247	937	33.95173631	813	35.93453929	857	0.766660361	0.380918687	normal	0.425644256	0.487251435	normal	0.305736042	0.512184252	normal	0.006821014	0.456224726	normal	[C]	Energy production and conversion	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: inorganic diphosphatase activity (GO:0004427);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: phosphate-containing compound metabolic process (GO:0006796);; 	K01507|0|pps:100986409|PPA2; pyrophosphatase (inorganic) 2; K01507 inorganic pyrophosphatase [EC:3.6.1.1] (A)	Oxidative phosphorylation (ko00190)	[C]	Energy production and conversion	Inorganic pyrophosphatase	"Inorganic pyrophosphatase 2, mitochondrial (Precursor) GN=PPA2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: inorganic pyrophosphatase 2, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000138778(CENPE)	--	7.708018417	1565	7.849649908	1557	9.207402988	1768	7.6546845	1498	6.857374005	1368	6.276517748	1209	0.981388112	-0.093863095	normal	0.963444476	-0.207911651	normal	0.140379427	-0.556016776	normal	0.089181901	-0.284635584	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K11498|0|pps:100983618|CENPE; centromere protein E, 312kDa; K11498 centromeric protein E (A)"	--	--	--	Kinesin motor domain	Centromere-associated protein E (Precursor) GN=CENPE OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: centromere-associated protein E isoform X1 [Galeopterus variegatus]
ENSG00000138780(GSTCD)	--	6.299272143	430	6.037753171	401	6.097540001	421	7.670935491	473	6.516601826	435	6.399980693	434	0.965325431	0.106309013	normal	0.964986333	0.095640247	normal	0.96980538	0.035457917	normal	0.811030987	0.078716708	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Cellular Component: cytoplasm (GO:0005737);; Biological Process: rRNA processing (GO:0006364);; Molecular Function: rRNA methyltransferase activity (GO:0008649);; 	--	--	--	--	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; rRNA small subunit methyltransferase G;; Methyltransferase TRM13;; Methyltransferase small domain	Glutathione S-transferase C-terminal domain-containing protein GN=GSTCD OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: glutathione S-transferase C-terminal domain-containing protein isoform X5 [Oryctolagus cuniculus]
ENSG00000138785(INTS12)	--	6.8088912	192	5.673838	160	8.220901	214	7.3317914	185	7.709245	227	6.2690229	185	0.96451073	-0.083730634	normal	0.693814196	0.479372463	normal	0.944836462	-0.216728184	normal	0.910957211	0.056245453	normal	--	--	--	"K13149|0|pon:100172088|INTS12, PHF22; integrator complex subunit 12; K13149 integrator complex subunit 12 (A)"	--	[R]	General function prediction only	PHD-finger	Integrator complex subunit 12 GN=INTS12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: integrator complex subunit 12 isoform X1 [Physeter catodon] 
ENSG00000138792(ENPEP)	--	0.072968949	8	0.146134346	16	0.109857617	11	0.171613798	19	0.114592829	12	0.09934433	12	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	"K11141|0|hsa:2028|ENPEP, APA, CD249, gp160; glutamyl aminopeptidase (aminopeptidase A) (EC:3.4.11.7); K11141 glutamyl aminopeptidase [EC:3.4.11.7] (A)"	Renin-angiotensin system (ko04614)	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	Glutamyl aminopeptidase GN=ENPEP OS=Homo sapiens (Human) PE=1 SV=3	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: glutamyl aminopeptidase [Panthera tigris altaica]
ENSG00000138794(CASP6)	--	10.16840956	274	10.62928017	249	10.08567007	264	13.22582875	362	14.12071087	365	9.85745018	269	0.822223752	0.369175657	normal	0.421320644	0.527662512	normal	0.967244464	0.018670846	normal	0.222715088	0.317852672	normal	--	--	--	"K04396|0|hsa:839|CASP6, MCH2; caspase 6, apoptosis-related cysteine peptidase (EC:3.4.22.59); K04396 caspase 6 [EC:3.4.22.59] (A)"	Apoptosis (ko04210)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain	Caspase-6 subunit p11 (Precursor) GN=CASP6 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-6 isoform 2 [Canis lupus familiaris]
ENSG00000138795(LEF1)	--	0	0	0	0	0	0	0.054642496	3	0	0	0.019670031	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K04492|0|ptr:461425|LEF1; lymphoid enhancer-binding factor 1; K04492 lymphoid enhancer-binding factor 1 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Melanogenesis (ko04916);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Basal cell carcinoma (ko05217);; Acute myeloid leukemia (ko05221);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[K]	Transcription	N-terminal CTNNB1 binding;; HMG (high mobility group) box;; HMG-box domain	Lymphoid enhancer-binding factor 1 GN=LEF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: lymphoid enhancer-binding factor 1 isoform X2 [Galeopterus variegatus]
ENSG00000138796(HADH)	--	16.984391	533	13.642223	435	15.37090754	487	20.04870856	637	19.11860989	604	19.5232632	620	0.940149299	0.225729776	normal	0.587565812	0.450771283	normal	0.846146296	0.339119542	normal	0.097071099	0.333824418	normal	[I]	Lipid transport and metabolism	"Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Biological Process: fatty acid metabolic process (GO:0006631);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00022|0|pps:100995262|HADH; hydroxyacyl-CoA dehydrogenase; K00022 3-hydroxyacyl-CoA dehydrogenase [EC:1.1.1.35] (A)	"Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Butanoate metabolism (ko00650);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	"3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain;; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus;; Alanine dehydrogenase/PNT, C-terminal domain;; Pyridine nucleotide-disulphide oxidoreductase;; UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (Precursor) GN=HADH OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: hydroxyacyl-coenzyme A dehydrogenase, mitochondrial isoform 1 [Odobenus rosmarus divergens]"
ENSG00000138798(EGF)	--	0.112346331	10	0.128874228	9	0.046286032	3	0.075555728	7	0.208320256	18	0.035140011	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K04357|0|pps:100975632|EGF; epidermal growth factor; K04357 epidermal growth factor (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; Hepatitis C (ko05160);; Pathways in cancer (ko05200);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; EGF-like domain;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; EGF domain	Epidermal growth factor (Precursor) GN=EGF OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pro-epidermal growth factor isoform X1 [Galeopterus variegatus]
ENSG00000138801(PAPSS1)	--	19.1066968	899	18.08494895	867	17.7655278	833	19.683741	933	19.51381744	918	16.36932089	768	0.978328393	0.022685645	normal	0.976265782	0.060932309	normal	0.969913147	-0.12526471	normal	0.980122653	-0.010759798	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: sulfate adenylyltransferase (ATP) activity (GO:0004781);; 	K13811|0|nle:100595002|PAPSS1; 3'-phosphoadenosine 5'-phosphosulfate synthase 1; K13811 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] (A)	Purine metabolism (ko00230);; Selenocompound metabolism (ko00450);; Sulfur metabolism (ko00920)	[F]	Nucleotide transport and metabolism	Adenylylsulphate kinase;; ATP-sulfurylase;; PUA-like domain;; AAA domain;; AAA domain	Adenylyl-sulfate kinase GN=PAPSS1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 [Ochotona princeps]
ENSG00000138802(SEC24B)	--	13.69330095	1020	14.264684	1043	14.45765139	1022	13.64320787	1024	13.36317784	989	11.31602611	858	0.979569907	-0.025147895	normal	0.97548551	-0.097977377	normal	0.931351326	-0.260216275	normal	0.579087196	-0.125428088	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: COPII vesicle coat (GO:0030127);; 	K14007|0|ptr:461431|SEC24B; SEC24 family member B; K14007 protein transport protein SEC24 (A)	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec23/Sec24 trunk domain;; Sec23/Sec24 helical domain;; Sec23/Sec24 beta-sandwich domain;; Sec23/Sec24 zinc finger;; Gelsolin repeat	Protein transport protein Sec24B GN=SEC24B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec24B [Panthera tigris altaica]
ENSG00000138814(PPP3CA)	--	24.42563748	1629	23.91515653	1753	21.942723	1589	24.4262976	1765	24.79013077	1805	25.7283812	1595	0.983109076	0.084772494	normal	0.98528675	0.020728661	normal	0.984686012	-0.002851434	normal	0.902498766	0.033656216	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K04348|0|fca:101097144|PPP3CA; protein phosphatase 3, catalytic subunit, alpha isozyme; K04348 serine/threonine-protein phosphatase 2B catalytic subunit [EC:3.1.3.16] (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Oocyte meiosis (ko04114);; Apoptosis (ko04210);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Oxytocin signaling pathway (ko04921);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; HTLV-I infection (ko05166)	[R]	General function prediction only	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform GN=PPP3CA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform isoform X1 [Felis catus] 
ENSG00000138821(SLC39A8)	--	10.6705189	510	11.969734	578	13.117461	624	26.0876	1262	23.39122	1120	33.390444	1614	3.67E-11	1.273791069	up	1.76E-05	0.931150112	normal	2.82E-13	1.360604054	up	7.23E-06	1.202603683	up	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14714|0|ptr:461405|SLC39A8; solute carrier family 39 (zinc transporter), member 8; K14714 solute carrier family 39 (zinc transporter), member 8 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP8 GN=SLC39A8 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	"PREDICTED: zinc transporter ZIP8, partial [Ceratotherium simum simum]"
ENSG00000138823(MTTP)	--	0.0323968	2	0.0161535	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: lipid transporter activity (GO:0005319);; Biological Process: lipid transport (GO:0006869);; 	"K14463|0|ptr:471397|MTTP, MTP; microsomal triglyceride transfer protein; K14463 microsomal triglyceride transfer protein large subunit (A)"	Fat digestion and absorption (ko04975)	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	Lipoprotein amino terminal region	Microsomal triglyceride transfer protein large subunit (Precursor) GN=MTTP OS=Homo sapiens (Human) PE=1 SV=1	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: microsomal triglyceride transfer protein large subunit [Galeopterus variegatus]
ENSG00000138829(FBN2)	--	21.98976553	3260	16.95327084	2707	21.30037488	3337	31.788323	5090	35.7091691	5506	30.35530122	4998	0.055648254	0.611728972	normal	3.31E-07	1.002482538	up	0.12719358	0.574293704	normal	2.73E-07	0.724115055	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; TB domain;; EGF-like domain;; Coagulation Factor Xa inhibitory site;; EGF domain	Fibrillin-2 (Precursor) GN=FBN2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: fibrillin-2 [Orcinus orca]
ENSG00000138834(MAPK8IP3)	--	7.112813544	1077	7.793585211	1203	6.673505	1070	9.234038775	1383	9.3819133	1369	11.63867401	1776	0.874879225	0.329534897	normal	0.970569966	0.164864866	normal	0.003026459	0.721929074	normal	0.045327915	0.414118436	normal	--	--	--	"K04436|0|hsa:23162|MAPK8IP3, JIP3, JSAP1, SYD2, syd; mitogen-activated protein kinase 8 interacting protein 3; K04436 mitogen-activated protein kinase 8 interacting protein 3 (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	JNK_SAPK-associated protein-1	C-Jun-amino-terminal kinase-interacting protein 3 GN=MAPK8IP3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: C-Jun-amino-terminal kinase-interacting protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000138835(RGS3)	--	8.483804378	497	7.405458018	472	7.910949009	539	12.73419002	663	13.77660606	671	9.739446219	521	0.762502189	0.383900212	normal	0.453525059	0.48479051	normal	0.970983247	-0.057130295	normal	0.186310023	0.277164421	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K07524|0|pon:100445111|RGS3; regulator of G-protein signaling 3; K07524 regulator of G-protein signalling 3 (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain;; C2 domain;; PDZ domain (Also known as DHR or GLGF)	Regulator of G-protein signaling 3 GN=RGS3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 3 isoform X1 [Galeopterus variegatus]
ENSG00000138867(GUCD1)	--	15.02426129	1027	15.49893504	1081	16.0579129	1136	18.2846855	1237	18.32758379	1264	17.0157028	1213	0.947350757	0.237253287	normal	0.960126289	0.203939325	normal	0.978716971	0.086214188	normal	0.380546174	0.174097105	normal	--	--	--	--	--	[S]	Function unknown	Guanylylate cyclase;; Peptidase_C39 like family	Protein GUCD1 GN=GUCD1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein GUCD1 isoform X1 [Tupaia chinensis]
ENSG00000138942(RNF185)	--	9.39691973	563	9.917421598	592	9.684784	573	10.23895763	613	10.80610862	636	12.240379	729	0.969564596	0.091680079	normal	0.970307536	0.081801403	normal	0.847145095	0.338298843	normal	0.460223608	0.174241156	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: metal ion binding (GO:0046872);; 	K10666|3.50285e-75|mmu:193670|Rnf185; ring finger protein 185; K10666 E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19] (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain;; Anaphase-promoting complex subunit 11 RING-H2 finger"	E3 ubiquitin-protein ligase RNF185 GN=RNF185 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF185-like isoform X6 [Balaenoptera acutorostrata scammoni]
ENSG00000138944(KIAA1644)	--	1.00864488	147	1.249925528	184	0.78733594	115	0.974763375	142	1.45874	210	0.4826698	70	0.966138336	-0.079907637	normal	0.953747969	0.1679641	normal	0.457891164	-0.712369009	normal	0.92546828	-0.102841766	normal	--	--	--	--	--	--	--	--	Uncharacterized protein KIAA1644 (Precursor) GN=KIAA1644 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: uncharacterized protein KIAA1644 homolog [Galeopterus variegatus]
ENSG00000138964(PARVG)	--	23.18950368	695	18.57871191	630	19.15663485	584	19.566593	643	21.94116016	697	18.25627297	543	0.964792713	-0.142698408	normal	0.966920883	0.124096979	normal	0.967002193	-0.113004062	normal	0.899494571	-0.041572389	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06275|0|hsa:64098|PARVG; parvin, gamma; K06275 parvin (A)"	Focal adhesion (ko04510)	[Z]	Cytoskeleton	Calponin homology (CH) domain;; CAMSAP CH domain	Gamma-parvin GN=PARVG OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: gamma-parvin [Galeopterus variegatus]
ENSG00000139044(B4GALNT3)	--	0.1399668	15	0.047076311	2	0.0929845	8	0.1911817	10	0.330931	27	0.0951424	7	--	--	--	0.002631325	3.004861669	up	--	--	--	--	--	--	--	--	Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: Golgi cisterna membrane (GO:0032580);; 	"K09656|0|hsa:283358|B4GALNT3; beta-1,4-N-acetyl-galactosaminyl transferase 3 (EC:2.4.1.244); K09656 beta-1,4-N-acetylgalactosaminyltransferase 3 [EC:2.4.1.244] (A)"	--	--	--	PA14 domain;; Chondroitin N-acetylgalactosaminyltransferase;; N-terminal domain of galactosyltransferase	"Beta-1,4-N-acetylgalactosaminyltransferase 3 GN=B4GALNT3 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-N-acetylgalactosaminyltransferase 3 [Odobenus rosmarus divergens]"
ENSG00000139083(ETV6)	--	5.316819	514	6.479549	591	6.540053	536	6.21034	599	6.703908	691	6.565411	627	0.952124847	0.189430489	normal	0.949387925	0.203618776	normal	0.943687529	0.217373411	normal	0.369106961	0.203201631	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K03211|0|nle:100586940|ETV6; ets variant 6; K03211 ETS translocation variant 6/7 (A)	Dorso-ventral axis formation (ko04320);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	Transcription factor ETV6 GN=ETV6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor ETV6 [Loxodonta africana]
ENSG00000139112(GABARAPL1)	--	29.75899232	828	30.90502308	882	21.72769283	725	30.88405827	887	37.56843285	1112	35.3823424	1052	0.975852308	0.068348528	normal	0.891441779	0.312401702	normal	0.235867837	0.527871175	normal	0.090516264	0.304440635	normal	--	--	Biological Process: autophagic vacuole assembly (GO:0000045);; Cellular Component: cytoplasm (GO:0005737);; 	K08341|1.75423e-63|phi:102114705|GABARAPL1; GABA(A) receptor-associated protein like 1; K08341 GABA(A) receptor-associated protein (A)	FoxO signaling pathway (ko04068);; Regulation of autophagy (ko04140)	[Z]	Cytoskeleton	Autophagy protein Atg8 ubiquitin like;; Ubiquitin-like autophagy protein Apg12	Gamma-aminobutyric acid receptor-associated protein-like 1 (Precursor) GN=GABARAPL1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: GABA(A) receptor-associated protein like 1, partial [Elephantulus edwardii]"
ENSG00000139116(KIF21A)	--	8.916326502	1026	9.903509932	1264	9.0218941	1123	11.21037079	1367	11.64621286	1361	11.19741309	1457	0.773335107	0.382652373	normal	0.979699543	0.08514586	normal	0.813853231	0.366916547	normal	0.113635795	0.27310305	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10395|0|pon:100174470|KIF21A; kinesin family member 21A; K10395 kinesin family member 4/21/27 (A)	--	[Z]	Cytoskeleton	"Kinesin motor domain;; WD domain, G-beta repeat"	Kinesin-like protein KIF21A GN=KIF21A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF21A isoform X2 [Galeopterus variegatus]
ENSG00000139117(CPNE8)	--	8.173530664	443	11.3311134	604	11.95112786	632	10.0107265	546	7.853779797	404	12.42804787	595	0.914995968	0.26991755	normal	0.115113169	-0.599770452	normal	0.969878952	-0.095091781	normal	0.737792794	-0.14076356	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-8 GN=CPNE8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: copine-8 [Felis catus] 
ENSG00000139131(YARS2)	--	15.52968	455	16.86138	475	20.92832	593	18.9301	546	19.78565	576	16.69274	481	0.936025568	0.23148782	normal	0.924148161	0.25597372	normal	0.88259235	-0.309408849	normal	0.875334373	0.052803421	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01866|0|pps:100973857|YARS2; tyrosyl-tRNA synthetase 2, mitochondrial; K01866 tyrosyl-tRNA synthetase [EC:6.1.1.1] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class I (W and Y)	"Tyrosine--tRNA ligase, mitochondrial (Precursor) GN=YARS2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tyrosine--tRNA ligase, mitochondrial [Galeopterus variegatus]"
ENSG00000139132(FGD4)	--	0.856351912	102	1.030400442	122	0.872651587	108	2.507691106	300	1.974314208	246	2.409441227	317	1.42E-09	1.511668445	up	0.001287762	0.981615633	normal	3.79E-10	1.53204176	up	1.56E-08	1.356962572	up	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Molecular Function: metal ion binding (GO:0046872);; 	"K05723|0|mcf:102121238|FGD4; FYVE, RhoGEF and PH domain containing 4; K05723 FYVE, RhoGEF and PH domain containing 4 (A)"	--	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; FYVE zinc finger	"FYVE, RhoGEF and PH domain-containing protein 4 GN=FGD4 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: FYVE, RhoGEF and PH domain-containing protein 4 [Balaenoptera acutorostrata scammoni]"
ENSG00000139133(ALG10)	--	3.887450377	363	7.44692	399	5.590893325	403	3.822815624	351	3.924887838	303	6.36538	410	0.965994636	-0.078990745	normal	0.726727464	-0.41667896	normal	0.969811002	0.016491275	normal	0.60784187	-0.151534955	normal	--	--	Molecular Function: dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity (GO:0004583);; Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: dolichol-linked oligosaccharide biosynthetic process (GO:0006488);; 	"K03850|0|hsa:84920|ALG10, ALG10A, DIE2, KCR1; ALG10, alpha-1,2-glucosyltransferase (EC:2.4.1.256); K03850 alpha-1,2-glucosyltransferase [EC:2.4.1.256] (A)"	N-Glycan biosynthesis (ko00510)	[OKIT]	"Posttranslational modification, protein turnover, chaperones;; Transcription;; Lipid transport and metabolism;; Signal transduction mechanisms"	DIE2/ALG10 family	"Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase GN=ALG10 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase [Lipotes vexillifer]"
ENSG00000139144(PIK3C2G)	--	0.02258522	1	0	0	0	0	0.145368468	4	0.046460083	3	0.095136415	3	--	--	--	--	--	--	--	--	--	--	--	--	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K00923|0|hsa:5288|PIK3C2G, PI3K-C2-gamma, PI3K-C2GAMMA; phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma (EC:2.7.1.154); K00923 phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	"Phosphatidylinositol 3- and 4-kinase;; Phosphoinositide 3-kinase family, accessory domain (PIK domain);; Phosphoinositide 3-kinase C2;; PX domain;; PI3-kinase family, ras-binding domain;; C2 domain"	Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma GN=PIK3C2G OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma isoform 1 [Ceratotherium simum simum]
ENSG00000139146(FAM60A)	--	25.49027215	1237	23.47574714	1067	27.74055906	1330	31.857207	1545	30.07271	1470	30.71966936	1416	0.921621135	0.289606678	normal	0.606493015	0.440295704	normal	0.980873049	0.082013188	normal	0.125013795	0.264911368	normal	--	--	--	--	--	--	--	Protein Family FAM60A	Protein FAM60A GN=FAM60A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM60A isoform X1 [Canis lupus familiaris]
ENSG00000139151(PLCZ1)	--	0	0	0	0	0	0	0.098588733	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05861|0|hsa:89869|PLCZ1, NYD-SP27, PLC-zeta-1, PLCzeta; phospholipase C, zeta 1 (EC:3.1.4.11); K05861 phosphatidylinositol phospholipase C, zeta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Thyroid hormone signaling pathway (ko04919)	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 OS=Homo sapiens (Human) PE=2 SV=1"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1 isoform X1 [Tupaia chinensis]"
ENSG00000139154(AEBP2)	--	16.91650186	878	17.23956317	870	15.79677424	821	17.84654806	965	19.9832423	1043	15.99108431	896	0.973940823	0.10529994	normal	0.94271656	0.239844096	normal	0.97179354	0.117617625	normal	0.472219628	0.155381229	normal	[R]	General function prediction only	--	K17452|0|ssc:100522805|AEBP2; AE binding protein 2; K17452 zinc finger protein AEBP2 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain"	Zinc finger protein AEBP2 GN=AEBP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein AEBP2 [Mustela putorius furo]
ENSG00000139155(SLCO1C1)	--	0	0	0	0	0	0	0	0	0.042040605	1	0.023504013	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08747|0|ptr:743769|SLCO1C1; solute carrier organic anion transporter family, member 1C1; K08747 solute carrier organic anion transporter family, member 1C (A)"	Thyroid hormone signaling pathway (ko04919)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain;; Sugar (and other) transporter	Solute carrier organic anion transporter family member 1C1 GN=SLCO1C1 OS=Homo sapiens (Human) PE=2 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 1C1 isoform 2 [Equus caballus]
ENSG00000139160(ETFBKMT)	--	1.225143	42	0.711654286	32	0.387879806	23	0.40911	19	0.672329744	20	0.686922653	26	0.575824113	-1.113171084	normal	0.951500072	-0.659719273	normal	0.985956084	0.158763179	normal	0.394099676	-0.598509949	normal	[R]	General function prediction only	--	--	--	--	--	Ribosomal protein L11 methyltransferase (PrmA);; Putative methyltransferase	Protein N-lysine methyltransferase METTL20 (Precursor) GN=METTL20 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: methyltransferase-like protein 20 [Ceratotherium simum simum]
ENSG00000139163(ETNK1)	--	21.4574025	1343	20.97367003	1713	27.06172116	1695	28.4721922	1984	27.62887787	1832	30.23464435	2178	0.214888331	0.53161725	normal	0.983715058	0.075403418	normal	0.862168793	0.353148588	normal	0.062928201	0.314477633	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Choline/ethanolamine kinase;; Phosphotransferase enzyme family;; Ecdysteroid kinase	Ethanolamine kinase 1 GN=ETNK1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: ethanolamine kinase 1 [Ceratotherium simum simum]
ENSG00000139168(ZCRB1)	--	33.203554	911	29.560553	858	34.360134	903	32.29843	927	31.68876308	866	42.075218	1137	0.978553658	-0.005704442	normal	0.97729415	-0.008023105	normal	0.876466791	0.323658851	normal	0.637209576	0.112418035	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	K13154|1.72994e-126|ptr:466960|ZCRB1; zinc finger CCHC-type and RNA binding motif 1; K13154 U11/U12 small nuclear ribonucleoprotein 31 kDa protein (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Zinc knuckle"	Zinc finger CCHC-type and RNA-binding motif-containing protein 1 GN=ZCRB1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: zinc finger CCHC-type and RNA-binding motif-containing protein 1 [Lipotes vexillifer]
ENSG00000139173(TMEM117)	--	2.47229365	116	2.858902545	103	2.947960631	105	3.388549833	114	3.826555822	133	2.771000284	123	0.968975268	-0.055185892	normal	0.917727523	0.342914297	normal	0.95542377	0.21708602	normal	0.739891009	0.170579043	normal	--	--	--	--	--	--	--	TMEM117 protein family	Transmembrane protein 117 GN=TMEM117 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 117 isoform X1 [Tupaia chinensis]
ENSG00000139174(PRICKLE1)	--	1.883685081	132	1.966887334	140	2.3627673	191	1.836008312	160	1.91925852	168	1.957140243	166	0.944274775	0.244117831	normal	0.942387843	0.239246029	normal	0.948358676	-0.208905054	normal	0.892992905	0.073067744	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K04511|0|hsa:144165|PRICKLE1, EPM1B, RILP; prickle homolog 1 (Drosophila); K04511 prickle (A)"	Wnt signaling pathway (ko04310)	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	PET Domain;; LIM domain	Prickle-like protein 1 (Precursor) GN=PRICKLE1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: prickle-like protein 1 isoform X1 [Canis lupus familiaris] 
ENSG00000139178(C1RL)	--	13.35171179	737	11.24561895	579	10.93838787	586	10.84761681	667	14.06321461	778	19.85251402	1067	0.959157792	-0.174427662	normal	0.717379867	0.403867293	normal	0.000129547	0.854637664	normal	0.340499156	0.381389787	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin;; CUB domain	Complement C1r subcomponent-like protein (Precursor) GN=C1RL OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: complement C1r subcomponent-like protein [Equus przewalskii]
ENSG00000139180(NDUFA9)	--	7.050105649	1043	11.34218317	1065	14.12833141	1030	15.70957148	1315	13.38333349	1242	17.08317161	1227	0.904013165	0.303093022	normal	0.960873638	0.200121837	normal	0.944468587	0.24387102	normal	0.164082334	0.248612055	normal	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K03953|0|hsa:4704|NDUFA9, CC6, CI-39k, CI39k, NDUFS2L, SDR22E1; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa; K03953 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 9 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	NAD dependent epimerase/dehydratase family;; 3-beta hydroxysteroid dehydrogenase/isomerase family;; NmrA-like family;; NADH(P)-binding;; RmlD substrate binding domain;; Male sterility protein	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial (Precursor) GN=NDUFA9 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial [Lipotes vexillifer]"
ENSG00000139182(CLSTN3)	--	10.4214631	1524	9.493576012	1469	10.021301	1431	9.418141	1397	12.2269085	1790	15.73068329	2337	0.97426519	-0.156198595	normal	0.944752231	0.263452602	normal	0.005176028	0.69875911	normal	0.445169855	0.300643919	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	--	--	[W]	Extracellular structures	Cadherin domain;; Concanavalin A-like lectin/glucanases superfamily	Calsyntenin-3 (Precursor) GN=CLSTN3 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: calsyntenin-3 [Felis catus]
ENSG00000139187(KLRG1)	--	2.017433223	37	2.114004143	39	2.0642477	36	1.28029747	21	2.023485356	33	1.1750888	23	0.902102281	-0.803129498	normal	0.977005659	-0.251806665	normal	0.950563242	-0.621726648	normal	0.402534623	-0.56140874	normal	--	--	--	"K10076|1.64136e-111|hsa:10219|KLRG1, 2F1, CLEC15A, MAFA, MAFA-2F1, MAFA-L, MAFA-LIKE; killer cell lectin-like receptor subfamily G, member 1; K10076 killer cell lectin-like receptor subfamily G member 1 (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	Killer cell lectin-like receptor subfamily G member 1 GN=KLRG1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: killer cell lectin-like receptor subfamily G member 1 [Orycteropus afer afer]
ENSG00000139190(VAMP1)	--	7.898812257	418	7.730359429	431	8.908491077	417	3.859948047	182	3.789588087	182	3.905730029	221	1.27E-07	-1.223376179	down	5.72E-08	-1.258165259	down	0.000345814	-0.919633257	normal	1.62E-08	-1.134430489	down	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K08510|9.94871e-56|ptr:749463|VAMP1; vesicle-associated membrane protein 1 (synaptobrevin 1); K08510 vesicle-associated membrane protein 1 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Synaptobrevin	Vesicle-associated membrane protein 1 GN=VAMP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000139192(TAPBPL)	--	1.82805873	60	2.223636	78	1.47767	52	2.853111	98	2.797078	95	2.760963	95	0.671221303	0.663574081	normal	0.954438139	0.25847987	normal	0.318425836	0.842733099	normal	0.18406458	0.578241639	normal	--	--	--	--	--	--	--	Immunoglobulin C1-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain	Tapasin-related protein (Precursor) GN=TAPBPL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: tapasin-related protein [Trichechus manatus latirostris]
ENSG00000139193(CD27)	--	0.0845801	2	0.0418279	1	0.081642	1	0	0	0.0412581	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05144|0|ptr:451780|CD27, TNFRSF7; CD27 molecule; K05144 tumor necrosis factor receptor superfamily member 7 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNFR/NGFR cysteine-rich region	CD27 antigen (Precursor) GN=CD27 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: CD27 antigen [Ceratotherium simum simum]
ENSG00000139194(RBP5)	--	1.30912	20	1.219344	19	0.902825	15	1.03946	18	1.441559	22	1.44572	25	0.988883247	-0.169132097	normal	0.986964622	0.176978877	normal	0.9685592	0.675445873	normal	0.817737445	0.246858375	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family	Retinol-binding protein 5 GN=RBP5 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: retinol-binding protein 5 isoform X1 [Myotis brandtii] 
ENSG00000139197(PEX5)	--	19.07059547	910	17.97429413	944	16.58344717	856	18.6829877	1026	21.42789962	1060	17.371173	843	0.970141443	0.142034086	normal	0.969774525	0.145558798	normal	0.977368477	-0.030315637	normal	0.713665456	0.090273391	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K13342|0|ptr:451812|PEX5; peroxisomal biogenesis factor 5; K13342 peroxin-5 (A)	Peroxisome (ko04146)	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Peroxisomal targeting signal 1 receptor GN=PEX5 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal targeting signal 1 receptor isoformX1 [Canis lupus familiaris]
ENSG00000139200(PIANP)	--	2.706597366	76	1.118533	49	6.321153704	71	0.46140523	18	3.008313933	61	0.5237092	23	8.45E-06	-2.018019577	down	0.964565114	0.286658768	normal	0.001896757	-1.572669551	down	0.141850332	-0.962107651	normal	--	--	--	--	--	--	--	AJAP1/PANP C-terminus	PILR alpha-associated neural protein (Precursor) GN=PIANP OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: PILR alpha-associated neural protein [Panthera tigris altaica]
ENSG00000139209(SLC38A4)	--	0.022075534	1	0.088052439	4	0.043931345	1	0.043733406	2	0.055018451	2	0.043819539	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K14991|0|hsa:55089|SLC38A4, ATA3, NAT3, PAAT, SNAT4; solute carrier family 38, member 4; K14991 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 4 (A)"	--	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Sodium-coupled neutral amino acid transporter 4 GN=SLC38A4 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: sodium-coupled neutral amino acid transporter 4-like [Leptonychotes weddellii]
ENSG00000139211(AMIGO2)	--	167.1589	9456	235.26974	13259	167.75187	9329	337.648	18888	376.37072	21016	448.7658952	24835	1.09E-06	0.967222454	normal	0.074755079	0.64303084	normal	9.99E-16	1.404143878	up	1.60E-05	0.993804047	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies);; Immunoglobulin domain	Amphoterin-induced protein 2 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: amphoterin-induced protein 2 [Galeopterus variegatus]
ENSG00000139218(SCAF11)	--	23.21417901	2360	27.00098886	2931	28.19720078	2745	29.6744498	3240	31.07510625	3191	32.10613304	3216	0.707594127	0.42613706	normal	0.987887255	0.101139061	normal	0.974036721	0.220057701	normal	0.161961662	0.242411437	normal	--	--	--	--	--	[R]	General function prediction only	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	Protein SCAF11 GN=SCAF11 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein SCAF11 [Ceratotherium simum simum]
ENSG00000139219(COL2A1)	--	0	0	0	0	0	0	0.00859094	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Molecular Function: protein binding (GO:0005515);; 	"K06236|0|ptr:451860|COL2A1; collagen, type II, alpha 1; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; von Willebrand factor type C domain	Chondrocalcin (Precursor) GN=COL2A1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: collagen alpha-1(II) chain isoform X2 [Galeopterus variegatus]
ENSG00000139220(PPFIA2)	--	0	0	0.031579916	2	0.159088615	2	0.012468102	1	0	0	0.0313098	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Liprin-alpha-2 GN=PPFIA2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: liprin-alpha-2 isoform X7 [Tupaia chinensis]
ENSG00000139233(LLPH)	--	26.0303256	903	24.75445011	926	25.33388008	860	28.95674019	1082	29.35384023	1044	22.52853018	880	0.947672773	0.229712915	normal	0.968590054	0.151378123	normal	0.977765709	0.024832254	normal	0.527836266	0.138891679	normal	--	--	--	--	--	[S]	Function unknown	Learning-associated protein	Protein LLP homolog GN=LLPH OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C12orf31 homolog [Lipotes vexillifer]
ENSG00000139263(LRIG3)	--	3.11070528	251	3.28095464	264	3.82323532	283	3.203607139	257	3.4008001	266	3.604513086	288	0.967185157	0.003229198	normal	0.966247499	-0.010478445	normal	0.967532805	0.016885869	normal	1	0.002628292	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Immunoglobulin I-set domain;; Leucine Rich repeats (2 copies);; Immunoglobulin domain;; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Immunoglobulin domain;; Immunoglobulin domain;; Leucine-rich repeat;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Leucine-rich repeats and immunoglobulin-like domains protein 3 (Precursor) GN=LRIG3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeats and immunoglobulin-like domains protein 3 [Galeopterus variegatus]
ENSG00000139266(MARCH9)	--	7.058031	380	4.46102	246	7.430208	383	10.805957	581	10.438767	514	9.346686	504	0.15184728	0.57979787	normal	1.05E-05	1.037176987	up	0.769652537	0.386453723	normal	0.00133371	0.643047249	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10659|9.03723e-165|hsa:92979|MARCH9, MARCH-IX, RNF179; membrane-associated ring finger (C3HC4) 9; K10659 E3 ubiquitin-protein ligase MARCH4/9/11 [EC:6.3.2.19] (A)"	--	--	--	RING-variant domain	E3 ubiquitin-protein ligase MARCH9 GN=MARCH9 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: E3 ubiquitin-protein ligase MARCH9 [Loxodonta africana]
ENSG00000139269(INHBE)	--	0.317615099	13	0.481569019	21	0.448733584	19	0.195747092	9	0.368219611	15	0.256112774	12	--	--	--	0.982617252	-0.466898483	normal	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04667|0|hsa:83729|INHBE; inhibin, beta E; K04667 inhibin, beta (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain;; TGF-beta propeptide	Inhibin beta E chain (Precursor) GN=INHBE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inhibin beta E chain [Ceratotherium simum simum]
ENSG00000139278(GLIPR1)	--	28.949748	817	24.38961	708	30.21913	987	118.357152	3697	100.110382	3148	69.56593	2253	0	2.145038963	up	0	2.128830282	up	2.59E-10	1.181202249	up	3.46E-07	1.834608432	up	[S]	Function unknown	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family	Glioma pathogenesis-related protein 1 (Precursor) GN=GLIPR1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: glioma pathogenesis-related protein 1 [Galeopterus variegatus]
ENSG00000139289(PHLDA1)	--	53.74042	4934	51.938461	4714	58.3924	5267	36.719656	3379	39.371517	3610	44.507913	4104	0.119350884	-0.576775153	normal	0.821854709	-0.406230069	normal	0.895205071	-0.368122105	normal	0.003173622	-0.447548925	normal	--	--	--	--	--	--	--	--	Pleckstrin homology-like domain family A member 1 GN=PHLDA1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology-like domain family A member 1 [Galeopterus variegatus]
ENSG00000139291(TMEM19)	--	23.45526932	1064	28.21269871	1229	23.21281674	1087	18.86667215	1076	20.31873911	1067	23.13964213	1088	0.980252537	-0.014631327	normal	0.952869278	-0.225053794	normal	0.980558758	-0.006955154	normal	0.722315465	-0.086325195	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Integral membrane protein DUF92	Transmembrane protein 19 GN=TMEM19 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 19 [Odobenus rosmarus divergens]
ENSG00000139292(LGR5)	--	0	0	0	0	0	0	0.029593004	2	0	0	0.014709101	1	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K04308|0|pps:100979934|LGR5; leucine-rich repeat containing G protein-coupled receptor 5; K04308 leucine-rich repeat-containing G protein-coupled receptor 5 (A)	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Leucine rich repeat;; 7 transmembrane receptor (rhodopsin family);; Leucine Rich repeat;; Leucine-rich repeat;; Leucine rich repeat N-terminal domain	Leucine-rich repeat-containing G-protein coupled receptor 5 (Precursor) GN=LGR5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing G-protein coupled receptor 5 isoform 1 [Odobenus rosmarus divergens]
ENSG00000139304(PTPRQ)	--	0.039456137	6	0.03363393	5	0.02009186	2	0.019913619	3	0.057298994	8	0.072416645	9	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K16910|0|pon:100447358|PTPRQ; protein tyrosine phosphatase, receptor type, Q; K16910 receptor-type tyrosine-protein phosphatase Q [EC:3.1.3.48] (A)"	--	--	--	"Fibronectin type III domain;; Protein-tyrosine phosphatase;; Interferon-alpha/beta receptor, fibronectin type III"	Phosphatidylinositol phosphatase PTPRQ (Precursor) GN=PTPRQ OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol phosphatase PTPRQ [Balaenoptera acutorostrata scammoni]
ENSG00000139318(DUSP6)	--	5.846008408	237	6.941722007	286	6.204252011	288	3.88897272	191	5.356491402	238	3.998374708	185	0.882411663	-0.339688049	normal	0.91139893	-0.284826506	normal	0.162364509	-0.642590071	normal	0.118441402	-0.422478423	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K04459|0|hsa:1848|DUSP6, HH19, MKP3, PYST1; dual specificity phosphatase 6 (EC:3.1.3.16 3.1.3.48); K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010);; Transcriptional misregulation in cancer (ko05202)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 6 GN=DUSP6 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 6 isoform X1 [Condylura cristata]
ENSG00000139323(POC1B)	--	12.47364592	721	13.08584133	775	13.75730839	736	14.381248	839	14.73645666	887	17.6214018	1100	0.957463045	0.187468703	normal	0.961742811	0.172995514	normal	0.117365307	0.570469347	normal	0.106150452	0.319998555	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	K16482|0|ptr:100608235|POC1B; POC1 centriolar protein B; K16482 centriolar protein POC1 (A)	--	--	--	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A;; Nucleoporin Nup120/160"	POC1 centriolar protein homolog B GN=POC1B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: POC1 centriolar protein homolog B isoform X1 [Galeopterus variegatus]
ENSG00000139324(TMTC3)	--	13.17386446	1314	14.77206659	1459	15.088974	1412	14.70892153	1516	13.642637	1318	15.404941	1571	0.970459376	0.175281292	normal	0.971321208	-0.167872897	normal	0.976129351	0.145503846	normal	0.840331581	0.052778742	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Domain of unknown function (DUF1736);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; ChAPs (Chs5p-Arf1p-binding proteins)"	Transmembrane and TPR repeat-containing protein 3 GN=TMTC3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane and TPR repeat-containing protein 3 [Ceratotherium simum simum]
ENSG00000139329(LUM)	--	0.0710927	3	0.0241177	1	0.168229	6	0.892432	38	1.66823	71	1.63882	70	4.07E-05	3.098536587	up	1.52E-14	4.836410659	up	3.95E-10	3.243497816	up	4.52E-09	4.144757795	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08122|0|hsa:4060|LUM, LDC, SLRR2D; lumican; K08122 lumican (A)"	Proteoglycans in cancer (ko05205)	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain;; Leucine rich repeats (6 copies)	Lumican (Precursor) GN=LUM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	lumican precursor [Oryctolagus cuniculus]
ENSG00000139343(SNRPF)	--	40.9377983	718	46.9201018	834	48.30210014	842	57.97210015	1046	47.74478	837	45.842018	813	0.295501159	0.511084014	normal	0.976842806	-0.016216966	normal	0.976028101	-0.058748934	normal	0.513488598	0.149486593	normal	[K]	Transcription	--	K11098|1.8908e-23|mcf:102141572|small nuclear ribonucleoprotein F-like; K11098 small nuclear ribonucleoprotein F (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	Small nuclear ribonucleoprotein F GN=SNRPF OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"Small nuclear ribonucleoprotein F, partial [Bos mutus]"
ENSG00000139344(AMDHD1)	--	4.992686752	128	3.041252	106	7.048662735	152	3.383883482	62	3.863813326	61	5.127361003	91	0.01031669	-1.057978039	normal	0.308299517	-0.803306538	normal	0.222046034	-0.738820061	normal	0.01309952	-0.870518217	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: hydrolase activity (GO:0016787);; 	K01468|0|hsa:144193|AMDHD1; amidohydrolase domain containing 1 (EC:3.5.2.7); K01468 imidazolonepropionase [EC:3.5.2.7] (A)	Histidine metabolism (ko00340)	[FQ]	"Nucleotide transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Amidohydrolase;; Amidohydrolase family;; Amidohydrolase family;; Amidohydrolase	Probable imidazolonepropionase GN=AMDHD1 OS=Homo sapiens (Human) PE=2 SV=2	F	Nucleotide transport and metabolism	PREDICTED: probable imidazolonepropionase [Equus przewalskii]
ENSG00000139350(NEDD1)	--	18.72672672	967	20.473161	1055	20.59111576	1066	17.84572122	973	16.03965582	786	18.128066	916	0.979017602	-0.021873702	normal	0.578561442	-0.445325856	normal	0.949095986	-0.226732028	normal	0.227552083	-0.228524571	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K16547|0|hsa:121441|NEDD1, GCP-WD, TUBGCP7; neural precursor cell expressed, developmentally down-regulated 1; K16547 protein NEDD1 (A)"	--	[T]	Signal transduction mechanisms	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Protein NEDD1 GN=NEDD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein NEDD1 isoform X1 [Physeter catodon]
ENSG00000139351(SYCP3)	--	0	0	0.052107761	1	0	0	0.154187525	3	0.181616005	2	0.051967945	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cor1/Xlr/Xmr conserved region	Synaptonemal complex protein 3 GN=SYCP3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: synaptonemal complex protein 3 isoform X1 [Leptonychotes weddellii]
ENSG00000139354(GAS2L3)	--	5.872730377	531	6.39650855	594	6.325091185	485	6.815007571	557	5.103522605	425	6.695983224	577	0.971960651	0.038025775	normal	0.398912428	-0.502905335	normal	0.932122975	0.241603641	normal	0.838590586	-0.06792578	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: microtubule binding (GO:0008017);; 	--	--	[Z]	Cytoskeleton	Growth-Arrest-Specific Protein 2 Domain;; Calponin homology (CH) domain	GAS2-like protein 3 GN=GAS2L3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: GAS2-like protein 3 [Galeopterus variegatus] 
ENSG00000139364(TMEM132B)	--	0.005693547	1	0	0	0	0	0	0	0.014256031	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K17599|0|nle:100606383|TMEM132B; transmembrane protein 132B; K17599 transmembrane protein 132 (A)	--	[S]	Function unknown	--	Transmembrane protein 132B GN=TMEM132B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 132B-like [Trichechus manatus latirostris]
ENSG00000139370(SLC15A4)	--	20.77486	718	19.45134	696	20.93866	734	21.27895	773	17.47925	625	21.6329	777	0.973678598	0.075496593	normal	0.957460829	-0.176253298	normal	0.974069271	0.073695502	normal	0.997342977	-0.003175342	normal	[E]	Amino acid transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14638|0|hsa:121260|SLC15A4, PHT1, PTR4; solute carrier family 15 (oligopeptide transporter), member 4; K14638 solute carrier family 15 (peptide/histidine transporter), member 3/4 (A)"	--	[E]	Amino acid transport and metabolism	POT family;; Major Facilitator Superfamily	Solute carrier family 15 member 4 GN=SLC15A4 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: solute carrier family 15 member 4 [Galeopterus variegatus]
ENSG00000139372(TDG)	--	10.95379941	575	12.35569007	650	9.516482598	495	16.06173185	852	17.13424059	899	13.14483009	693	0.226535952	0.535277488	normal	0.580828929	0.445569873	normal	0.466880319	0.475901009	normal	0.014196969	0.484737819	normal	[L]	"Replication, recombination and repair"	--	K03649|0|ptr:452188|TDG; thymine-DNA glycosylase; K03649 TDG/mug DNA glycosylase family protein [EC:3.2.2.-] (A)	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	Uracil DNA glycosylase superfamily	G/T mismatch-specific thymine DNA glycosylase GN=TDG OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: G/T mismatch-specific thymine DNA glycosylase [Felis catus]
ENSG00000139405(RITA1)	--	16.9154687	639	20.8594064	790	19.5650829	746	18.539565	708	18.74149	714	20.29905	791	0.968553091	0.116834219	normal	0.961476775	-0.16701865	normal	0.974121156	0.076060865	normal	0.996010527	0.004157334	normal	--	--	Biological Process: Notch signaling pathway (GO:0007219);; Molecular Function: tubulin binding (GO:0015631);; Biological Process: nuclear export (GO:0051168);; 	--	--	--	--	--	RBPJ-interacting and tubulin-associated protein 1 GN=RITA1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RBPJ-interacting and tubulin-associated protein 1 [Felis catus]
ENSG00000139410(SDSL)	--	9.986937102	218	9.12981485	211	9.870068368	213	19.01622748	454	20.33016444	455	19.145927	453	2.12E-05	1.022433526	up	5.90E-06	1.081792592	up	5.20E-06	1.075010583	up	6.18E-08	1.063886168	up	[E]	Amino acid transport and metabolism	--	"K17989|0|hsa:113675|SDSL, SDH_2, SDS-RS1, TDH, cSDH; serine dehydratase-like (EC:4.3.1.17 4.3.1.19); K17989 L-serine/L-threonine ammonia-lyase [EC:4.3.1.17 4.3.1.19] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Cysteine and methionine metabolism (ko00270);; Valine, leucine and isoleucine biosynthesis (ko00290);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Pyridoxal-phosphate dependent enzyme	Serine dehydratase-like GN=SDSL OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: serine dehydratase-like [Ceratotherium simum simum]
ENSG00000139428(MMAB)	--	14.038962	605	16.173737	611	17.413728	695	10.397449	397	12.18539	412	19.013795	770	0.054147451	-0.636616413	normal	0.136610549	-0.588169511	normal	0.966699306	0.139266015	normal	0.584775034	-0.294256891	normal	[S]	Function unknown	--	"K00798|1.85481e-157|hsa:326625|MMAB, ATR, CFAP23, cblB, cob; methylmalonic aciduria (cobalamin deficiency) cblB type (EC:2.5.1.17); K00798 cob(I)alamin adenosyltransferase [EC:2.5.1.17] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	--	--	Cobalamin adenosyltransferase	"Cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial (Precursor) GN=MMAB OS=Homo sapiens (Human) PE=1 SV=1"	H	Coenzyme transport and metabolism	"PREDICTED: cob(I)yrinic acid a,c-diamide adenosyltransferase, mitochondrial [Galeopterus variegatus]"
ENSG00000139433(GLTP)	--	22.24747611	714	20.82279446	682	20.68441442	714	31.64777038	1100	26.2517836	879	27.00189374	961	0.079273794	0.591642389	normal	0.843902392	0.343991407	normal	0.656934243	0.419552249	normal	0.005131612	0.456928433	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Molecular Function: glycolipid transporter activity (GO:0017089);; Biological Process: glycolipid transport (GO:0046836);; Molecular Function: glycolipid binding (GO:0051861);; 	--	--	[G]	Carbohydrate transport and metabolism	Glycolipid transfer protein (GLTP)	Glycolipid transfer protein GN=GLTP OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: glycolipid transfer protein isoform X2 [Mustela putorius furo] 
ENSG00000139436(GIT2)	--	11.68100338	1190	12.15751254	1270	12.2416196	1231	13.48437093	1407	12.44725237	1290	14.38726276	1516	0.960209063	0.210578238	normal	0.981930029	0.001114694	normal	0.919699841	0.291823945	normal	0.388276341	0.169815786	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	K12487|0|pps:100980171|GIT2; G protein-coupled receptor kinase interacting ArfGAP 2; K12487 G protein-coupled receptor kinase interactor 2 (A)	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	G protein-coupled receptor kinase-interacting protein 1 C term;; Spa2 homology domain (SHD) of GIT;; Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies)	ARF GTPase-activating protein GIT2 GN=GIT2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ARF GTPase-activating protein GIT2 isoform X1 [Ailuropoda melanoleuca]
ENSG00000139437(TCHP)	--	6.629668	483	6.100924582	445	7.535415132	563	8.895711213	666	8.450790052	614	7.916222	590	0.630497986	0.431493495	normal	0.615857109	0.441723826	normal	0.971781222	0.059133417	normal	0.136546442	0.305562246	normal	--	--	--	"K16811|0|hsa:84260|TCHP, TpMs; trichoplein, keratin filament binding; K16811 trichoplein keratin filament-binding protein (A)"	--	--	--	"Tumour suppressor, Mitostatin"	Trichoplein keratin filament-binding protein OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: trichoplein keratin filament-binding protein isoform X1 [Tupaia chinensis]
ENSG00000139438(FAM222A)	--	1.559956081	92	1.7011395	108	1.144513946	70	1.585181691	99	2.143128875	135	1.032401612	66	0.970335404	0.073774597	normal	0.933507808	0.29677812	normal	0.973795841	-0.091151956	normal	0.866978052	0.129437588	normal	--	--	--	--	--	--	--	Protein family of FAM222A	Protein FAM222A GN=FAM222A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM222A [Pteropus alecto]
ENSG00000139445(FOXN4)	--	0.114924448	7	0	0	0.015961195	0	0.016474323	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09407|0|hsa:121643|FOXN4; forkhead box N4; K09407 forkhead box protein N (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein N4 GN=FOXN4 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: forkhead box protein N4 [Galeopterus variegatus]
ENSG00000139496(NUP58)	--	19.9680195	1430	19.93974752	1449	20.82929161	1465	17.50080732	1315	17.82828942	1319	16.094369	1190	0.97400435	-0.151614665	normal	0.973067182	-0.15686791	normal	0.903790249	-0.307877235	normal	0.266048494	-0.205371087	normal	--	--	--	K14307|0|pps:100986670|NUPL1; nucleoporin like 1; K14307 nucleoporin p58/p45 (A)	RNA transport (ko03013)	--	--	--	Nucleoporin p58/p45 GN=NUPL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nucleoporin p58/p45 [Ceratotherium simum simum]
ENSG00000139505(MTMR6)	--	8.4458701	703	8.583595483	710	8.88803967	726	9.136329173	770	8.825995313	739	8.713199675	727	0.971497514	0.100292018	normal	0.974698064	0.036253094	normal	0.975900355	-0.006292528	normal	0.891024712	0.042663386	normal	--	--	--	K18083|0|pps:100987222|MTMR6; myotubularin related protein 6; K18083 myotubularin-related protein 6/7/8 [EC:3.1.3.-] (A)	--	[R]	General function prediction only	Myotubularin-like phosphatase domain	Myotubularin-related protein 6 GN=MTMR6 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: myotubularin-related protein 6 [Odobenus rosmarus divergens]
ENSG00000139508(SLC46A3)	--	3.317448751	127	4.731238664	179	3.809770956	146	6.12014678	237	6.5153946	251	9.11233047	361	0.011263109	0.861483362	normal	0.704661064	0.462983897	normal	7.81E-08	1.288963112	up	0.013821678	0.889355493	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14613|0|hsa:283537|SLC46A3, FKSG16; solute carrier family 46, member 3; K14613 MFS transporter, PCFT/HCP family, solute carrier family 46 (folate transporter), member 1/3 (A)"	--	[R]	General function prediction only	Major Facilitator Superfamily	Solute carrier family 46 member 3 (Precursor) GN=SLC46A3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: solute carrier family 46 member 3 [Odobenus rosmarus divergens]
ENSG00000139514(SLC7A1)	--	22.00212996	2853	23.44320797	2964	21.06785885	2802	19.86078174	2621	18.85574029	2485	28.88253084	3834	0.983271827	-0.153108593	normal	0.953609876	-0.275572368	normal	0.660202446	0.443896319	normal	0.955905284	0.032614624	normal	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13863|0|hsa:6541|SLC7A1, ATRC1, CAT-1, ERR, HCAT1, REC1L; solute carrier family 7 (cationic amino acid transporter, y+ system), member 1; K13863 solute carrier family 7 (cationic amino acid transporter), member 1 (A)"	MicroRNAs in cancer (ko05206)	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease;; C-terminus of AA_permease	High affinity cationic amino acid transporter 1 GN=SLC7A1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: high affinity cationic amino acid transporter 1 [Ceratotherium simum simum]
ENSG00000139515(PDX1)	--	0	0	0.136992	5	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K07594|1.02912e-123|hsa:3651|PDX1, GSF, IDX-1, IPF1, IUF1, MODY4, PAGEN1, PDX-1, STF-1; pancreatic and duodenal homeobox 1; K07594 insulin promoter factor 1 (A)"	Insulin secretion (ko04911);; Type II diabetes mellitus (ko04930);; Maturity onset diabetes of the young (ko04950)	[R]	General function prediction only	Homeobox domain	Pancreas/duodenum homeobox protein 1 GN=PDX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: pancreas/duodenum homeobox protein 1 [Equus caballus]
ENSG00000139517(LNX2)	--	2.38757982	179	2.3319667	177	2.673489655	200	3.040279768	224	2.85287895	216	2.871526354	219	0.91760694	0.290474375	normal	0.928644633	0.263812201	normal	0.960973802	0.121759338	normal	0.531012117	0.224141717	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K10692|0|hsa:222484|LNX2, PDZRN1; ligand of numb-protein X 2; K10692 ligand of Numb protein X 1/2 (A)"	--	[S]	Function unknown	"PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	Ligand of Numb protein X 2 GN=LNX2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ligand of Numb protein X 2 isoform X2 [Equus przewalskii]
ENSG00000139531(SUOX)	--	8.611595798	362	10.00475022	358	9.294630264	340	7.313632389	336	7.907029143	344	7.223733891	324	0.959287025	-0.137753647	normal	0.965046584	-0.078638664	normal	0.965759279	-0.077479307	normal	0.771785816	-0.099677227	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: molybdenum ion binding (GO:0030151);; Biological Process: nitrate assimilation (GO:0042128);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00387|0|hsa:6821|SUOX; sulfite oxidase (EC:1.8.3.1); K00387 sulfite oxidase [EC:1.8.3.1] (A)	Sulfur metabolism (ko00920)	[C]	Energy production and conversion	Oxidoreductase molybdopterin binding domain;; Mo-co oxidoreductase dimerisation domain;; Cytochrome b5-like Heme/Steroid binding domain	"Sulfite oxidase, mitochondrial (Precursor) GN=SUOX OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"sulfite oxidase, mitochondrial [Camelus ferus]"
ENSG00000139537(CCDC65)	--	0.3396739	14	0.361260066	14	0.558797222	21	0.622078	26	0.603135	24	0.70524296	30	0.955566277	0.79723744	normal	0.967480046	0.698033852	normal	0.974514769	0.477387824	normal	0.353397633	0.687184485	normal	--	--	--	--	--	--	--	Sperm tail	Coiled-coil domain-containing protein 65 GN=CCDC65 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 65 [Galeopterus variegatus]
ENSG00000139540(SLC39A5)	--	0.034923557	1	0	0	0	0	0.034914381	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14711|1.99897e-170|hsa:283375|SLC39A5, LZT-Hs7, MYP24, ZIP5; solute carrier family 39 (zinc transporter), member 5; K14711 solute carrier family 39 (zinc transporter), member 5 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP5 (Precursor) GN=SLC39A5 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP5 [Galeopterus variegatus]
ENSG00000139546(TARBP2)	--	14.4811522	371	18.53717896	435	16.9409496	445	20.68705903	516	18.6661186	454	19.95102984	499	0.617711611	0.443555936	normal	0.969149844	0.040113831	normal	0.958375536	0.156440735	normal	0.395769503	0.210555614	normal	--	--	--	K18420|0|ptr:736926|TARBP2; TAR (HIV-1) RNA binding protein 2; K18420 RISC-loading complex subunit TARBP2 (A)	--	[UK]	"Intracellular trafficking, secretion, and vesicular transport;; Transcription"	Double-stranded RNA binding motif;; double strand RNA binding domain from DEAD END PROTEIN 1	RISC-loading complex subunit TARBP2 {ECO:0000255|HAMAP-Rule:MF_03034} OS=Homo sapiens (Human) PE=1 SV=3	KU	"Transcription;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: RISC-loading complex subunit TARBP2 isoform X1 [Felis catus]
ENSG00000139547(RDH16)	--	0.0937813	4	0.157435	7	0.0225416	0	0.0464397	2	0	0	0.0234243	1	--	--	--	--	--	--	--	--	--	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K11154|0|hsa:8608|RDH16, RODH-4, SDR9C8; retinol dehydrogenase 16 (all-trans); K11154 retinol dehydrogenase 16 [EC:1.1.1.-] (A)"	Retinol metabolism (ko00830)	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase	Retinol dehydrogenase 16 GN=RDH16 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: retinol dehydrogenase 16-like [Ceratotherium simum simum]
ENSG00000139549(DHH)	--	0.0361713	1	0.0343174	1	0	0	0.140916	4	0.0349343	0	0.0355036	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: proteolysis (GO:0006508);; Biological Process: cell-cell signaling (GO:0007267);; Molecular Function: peptidase activity (GO:0008233);; 	K11990|0|pps:100969105|DHH; desert hedgehog; K11990 desert hedgehog (A)	Hedgehog signaling pathway (ko04340)	[T]	Signal transduction mechanisms	Hedgehog amino-terminal signalling domain;; Hint module	Desert hedgehog protein C-product (Precursor) GN=DHH OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	Protein LMBR1L [Tupaia chinensis]
ENSG00000139567(ACVRL1)	--	0.014124696	1	0.027107514	1	0	0	0.876446268	7	0.056410573	2	0.013966694	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	K13594|0|ptr:451910|ACVRL1; activin A receptor type II-like 1; K13594 activin receptor-like kinase 1 [EC:2.7.11.30] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Transforming growth factor beta type I GS-motif;; Activin types I and II receptor domain	Serine/threonine-protein kinase receptor R3 (Precursor) GN=ACVRL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase receptor R3 isoform X1 [Canis lupus familiaris]
ENSG00000139572(GPR84)	--	0	0	0.0269365	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08421|0|hsa:53831|GPR84, EX33, GPCR4; G protein-coupled receptor 84; K08421 G protein-coupled receptor 84 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srx;; Serpentine type 7TM GPCR chemoreceptor Srsx	G-protein coupled receptor 84 GN=GPR84 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 84 [Orycteropus afer afer]
ENSG00000139574(NPFF)	--	10.3455902	691	12.9234193	845	12.83293248	728	11.91215099	757	11.3309085	811	13.66450353	896	0.971253685	0.10056166	normal	0.974156229	-0.080528858	normal	0.90565303	0.290723549	normal	0.688756215	0.101313676	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Molecular Function: neuropeptide hormone activity (GO:0005184);; 	"K05247|2.83313e-66|hsa:8620|NPFF, FMRFAL; neuropeptide FF-amide peptide precursor; K05247 neuropeptide FF-amide peptide (A)"	--	--	--	Neuropeptide FF	Neuropeptide AF (Precursor) GN=NPFF OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: pro-FMRFamide-related neuropeptide FF [Loxodonta africana]
ENSG00000139579(NABP2)	--	44.17416	1232	42.753025	1214	42.629243	1250	51.39193	1468	46.75818	1295	50.411823	1437	0.957392454	0.221763847	normal	0.979921005	0.071670668	normal	0.965898691	0.192623014	normal	0.411645173	0.163158635	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	OB-fold nucleic acid binding domain	SOSS complex subunit B1 GN=NABP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SOSS complex subunit B1 [Ochotona princeps]
ENSG00000139597(N4BP2L1)	--	0.633719168	13	0.704392083	11	0.5803184	8	0.165733071	3	0.946270355	16	0.818728308	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ATP binding (GO:0005524);; Molecular Function: kinase activity (GO:0016301);; 	--	--	[L]	"Replication, recombination and repair"	AAA domain;; AAA domain;; Zeta toxin;; AAA domain	NEDD4-binding protein 2-like 1 GN=N4BP2L1 OS=Homo sapiens (Human) PE=2 SV=1	L	"Replication, recombination and repair"	PREDICTED: NEDD4-binding protein 2-like 1 isoform 1 [Ceratotherium simum simum]
ENSG00000139613(SMARCC2)	--	26.004286	3100	25.18844229	3006	25.42945609	3046	22.43347101	2680	22.59610313	2702	22.875786	2749	0.968011747	-0.240739008	normal	0.98104419	-0.175150896	normal	0.983611177	-0.156218795	normal	0.300438778	-0.191760975	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11649|0|ptr:451985|SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; K11649 SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C (A)"	--	[B]	Chromatin structure and dynamics	SWIRM domain;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain	SWI/SNF complex subunit SMARCC2 GN=SMARCC2 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF complex subunit SMARCC2 isoform 2 [Orcinus orca]
ENSG00000139618(BRCA2)	--	3.621796355	833	3.741991529	842	4.529606737	1005	2.526529714	582	2.557241113	588	2.609690894	601	0.190026323	-0.546915558	normal	0.234059935	-0.538267067	normal	0.002439546	-0.748577023	normal	0.000108786	-0.618424493	normal	--	--	Biological Process: double-strand break repair via homologous recombination (GO:0000724);; 	"K08775|0|hsa:675|BRCA2, BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11; breast cancer 2, early onset; K08775 breast cancer 2 susceptibility protein (A)"	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460);; Pathways in cancer (ko05200);; Pancreatic cancer (ko05212)	[L]	"Replication, recombination and repair"	"BRCA2, helical;; BRCA2 repeat;; BRCA2, oligonucleotide/oligosaccharide-binding, domain 3;; BRCA2, oligonucleotide/oligosaccharide-binding, domain 1;; Tower"	Breast cancer type 2 susceptibility protein GN=BRCA2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: breast cancer type 2 susceptibility protein [Galeopterus variegatus]
ENSG00000139620(KANSL2)	--	12.5315932	428	10.22036267	394	10.01918325	416	13.96254644	494	13.57788206	551	14.12569519	555	0.953831696	0.175481283	normal	0.563733515	0.460927759	normal	0.717420372	0.406329724	normal	0.097831133	0.349289155	normal	--	--	--	K18401|0|mcf:102146410|KANSL2; KAT8 regulatory NSL complex subunit 2; K18401 KAT8 regulatory NSL complex subunit 2 (A)	--	--	--	Potential DNA-binding domain	KAT8 regulatory NSL complex subunit 2 GN=KANSL2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: KAT8 regulatory NSL complex subunit 2 isoform 1 [Ovis aries]
ENSG00000139624(CERS5)	--	20.31269523	652	19.77387644	593	19.55383272	628	25.18081146	794	22.445034	715	21.52691373	689	0.929953991	0.252894072	normal	0.931340447	0.247908121	normal	0.967339824	0.125160145	normal	0.329164226	0.209235551	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: DNA binding (GO:0003677);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04710|0|pon:100454836|CERS5, LASS5; ceramide synthase 5; K04710 ceramide synthetase [EC:2.3.1.24] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TLC domain;; Homeobox domain	Ceramide synthase 5 GN=CERS5 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ceramide synthase 5 [Camelus bactrianus]
ENSG00000139625(MAP3K12)	--	12.298636	1066	13.39927509	1150	11.62254664	1014	10.3782951	924	10.13679001	888	10.92125102	961	0.944719506	-0.236708096	normal	0.747976836	-0.39383764	normal	0.976591852	-0.085609587	normal	0.191160967	-0.241350766	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04423|0|hsa:7786|MAP3K12, DLK, MEKK12, MUK, ZPK, ZPKP1; mitogen-activated protein kinase kinase kinase 12 (EC:2.7.11.25); K04423 mitogen-activated protein kinase kinase kinase 12 [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Mitogen-activated protein kinase kinase kinase 12 GN=MAP3K12 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 12 isoform X1 [Oryctolagus cuniculus]
ENSG00000139626(ITGB7)	--	0.29922	11	0.432761351	12	0.358884111	7	0.331718326	9	0.0902957	4	0.188057147	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06590|0|hsa:3695|ITGB7; integrin, beta 7; K06590 integrin beta 7 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Intestinal immune network for IgA production (ko04672);; Regulation of actin cytoskeleton (ko04810);; Transcriptional misregulation in cancer (ko05202);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; Integrin beta cytoplasmic domain"	Integrin beta-7 (Precursor) GN=ITGB7 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: integrin beta-7 [Galeopterus variegatus]
ENSG00000139629(GALNT6)	--	8.514956006	512	3.959072612	317	7.773623412	444	1.914137158	200	5.113371622	363	2.035316933	145	2.04E-10	-1.380094381	down	0.951682326	0.173287171	normal	4.62E-13	-1.61267813	down	0.09316514	-0.86768522	normal	--	--	--	"K00710|0|hsa:11226|GALNT6, GALNAC-T6, GalNAcT6; polypeptide N-acetylgalactosaminyltransferase 6 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 6 GN=GALNT6 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 6 [Galeopterus variegatus]
ENSG00000139631(CSAD)	--	3.636560504	206	4.25062671	190	6.855569642	275	3.39026993	210	5.968839005	251	5.213184	274	0.966976317	-0.003064635	normal	0.842088356	0.377638829	normal	0.967418429	-0.013472942	normal	0.785295833	0.111694393	normal	[E]	Amino acid transport and metabolism	Biological Process: cellular amino acid metabolic process (GO:0006520);; Molecular Function: lyase activity (GO:0016829);; Molecular Function: carboxy-lyase activity (GO:0016831);; Biological Process: carboxylic acid metabolic process (GO:0019752);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K01594|0|hsa:51380|CSAD, CSD, PCAP; cysteine sulfinic acid decarboxylase (EC:4.1.1.29); K01594 sulfinoalanine decarboxylase [EC:4.1.1.29] (A)"	Taurine and hypotaurine metabolism (ko00430)	[E]	Amino acid transport and metabolism	Pyridoxal-dependent decarboxylase conserved domain;; Aminotransferase class-V;; Beta-eliminating lyase	Cysteine sulfinic acid decarboxylase GN=CSAD OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	hypothetical protein PANDA_012433 [Ailuropoda melanoleuca]
ENSG00000139636(LMBR1L)	--	5.017974993	203	5.956025387	197	6.740363343	244	8.02445157	291	6.958418486	259	6.467857901	252	0.609146497	0.485622874	normal	0.846947752	0.370840353	normal	0.966597621	0.038019269	normal	0.322039577	0.295260605	normal	--	--	--	--	--	[V]	Defense mechanisms	LMBR1-like membrane protein	Protein LMBR1L GN=LMBR1L OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: protein LMBR1L [Tupaia chinensis]
ENSG00000139637(C12orf10)	--	33.794271	644	33.3501764	662	37.1219033	663	36.3333209	601	39.67989912	705	31.44271106	567	0.965800023	-0.130206298	normal	0.972485206	0.06921226	normal	0.937739299	-0.233375325	normal	0.731290332	-0.093345212	normal	--	--	--	--	--	[R]	General function prediction only	Uncharacterised protein family (UPF0160)	"UPF0160 protein MYG1, mitochondrial (Precursor) GN=C12orf10 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: UPF0160 protein MYG1, mitochondrial [Camelus bactrianus]"
ENSG00000139644(TMBIM6)	--	304.1393254	12236	293.6259411	11864	271.922109	11296	414.1626862	17317	406.6004275	17087	423.3568028	17622	0.769457633	0.470174898	normal	0.645274923	0.504828169	normal	0.067998444	0.633205818	normal	0.001276371	0.534396903	normal	--	--	--	--	--	[V]	Defense mechanisms	Inhibitor of apoptosis-promoting Bax1	Bax inhibitor 1 GN=TMBIM6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: bax inhibitor 1 [Orycteropus afer afer]
ENSG00000139645(ANKRD52)	--	23.0653	4027	22.6233	3997	24.1333	4248	29.1734	5055	26.7648	4611	27.2431	4755	0.957096474	0.297072017	normal	0.984913992	0.184670439	normal	0.988298279	0.154318182	normal	0.250144511	0.211499893	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15504|0|hsa:283373|ANKRD52, ANKRD33; ankyrin repeat domain 52; K15504 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C GN=ANKRD52 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C isoform X1 [Bubalus bubalis]
ENSG00000139648(KRT71)	--	0	0	0	0	0	0	0.020057	1	0.0390297	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|pon:100172067|KRT71; keratin 71; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 71 GN=KRT71 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: keratin, type II cytoskeletal 71 [Tupaia chinensis]"
ENSG00000139651(ZNF740)	--	7.326025	845	7.844725124	913	7.475335211	865	7.301586611	824	8.823777554	988	9.827102897	1114	0.97560578	-0.067015864	normal	0.975054875	0.092322599	normal	0.824703243	0.356135706	normal	0.570902998	0.137400331	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 740 GN=ZNF740 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 740 isoform X1 [Equus caballus] 
ENSG00000139668(WDFY2)	--	10.23518356	653	8.83276114	521	8.361483026	643	5.67913428	521	7.1375014	505	4.53604411	412	0.818378918	-0.35569259	normal	0.969343715	-0.066231262	normal	0.041026895	-0.648544216	normal	0.070464581	-0.359123084	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat;; FYVE zinc finger"	WD repeat and FYVE domain-containing protein 2 GN=WDFY2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: WD repeat and FYVE domain-containing protein 2 isoform X2 [Oryctolagus cuniculus]
ENSG00000139675(HNRNPA1L2)	--	2.734382	144	2.800319	144	2.710107	142	2.88717	152	3.080656	161	2.232498954	119	0.967315051	0.046685408	normal	0.959841057	0.138192293	normal	0.943179635	-0.260189744	normal	0.986272296	-0.015127108	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12741|1.52106e-139|hsa:144983|HNRNPA1L2; heterogeneous nuclear ribonucleoprotein A1-like 2; K12741 heterogeneous nuclear ribonucleoprotein A1/A3 (A)	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Nuclear factor hnRNPA1"	Heterogeneous nuclear ribonucleoprotein A1-like 2 GN=HNRNPA1L2 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein A1 isoform X1 [Galeopterus variegatus] 
ENSG00000139679(LPAR6)	--	1.366847623	42	0.726051207	22	0.989527849	29	1.316026116	41	2.040327539	63	1.12267491	35	0.981133231	-0.063255511	normal	0.017978544	1.435672741	normal	0.980319804	0.251077452	normal	0.366634255	0.558432773	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04273|0|ptr:741241|LPAR6, P2RY5; lysophosphatidic acid receptor 6; K04273 lysophosphatidic acid receptor 6 (A)"	Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Pathways in cancer (ko05200)	--	--	7 transmembrane receptor (rhodopsin family)	Lysophosphatidic acid receptor 6 GN=LPAR6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: lysophosphatidic acid receptor 6 [Oryctolagus cuniculus]
ENSG00000139684(ESD)	--	60.27004517	1165	61.92776633	1211	63.48771647	1237	70.41473792	1354	61.16520078	1146	60.58281579	1143	0.966206175	0.185838029	normal	0.977205171	-0.100888843	normal	0.975765302	-0.122156132	normal	0.980890621	-0.009763077	normal	[R]	General function prediction only	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; 	"K01070|0|hsa:2098|ESD, FGH; esterase D (EC:3.1.2.12 3.1.1.56); K01070 S-formylglutathione hydrolase [EC:3.1.2.12] (A)"	Carbon metabolism (ko01200)	[R]	General function prediction only	Putative esterase;; Alpha/beta hydrolase family;; Prolyl oligopeptidase family;; Chlorophyllase enzyme;; Esterase PHB depolymerase;; Acetyl xylan esterase (AXE1)	S-formylglutathione hydrolase GN=ESD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: S-formylglutathione hydrolase isoform X1 [Leptonychotes weddellii]
ENSG00000139687(RB1)	--	14.44945	1111	15.04227	1142	15.94337	1191	15.31868	1192	13.061048	1011	14.738189	1144	0.979349307	0.070598891	normal	0.960448711	-0.19692884	normal	0.979806653	-0.066291909	normal	0.81162932	-0.062507788	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of cell cycle (GO:0051726);; 	K06618|0|pps:100973837|RB1; retinoblastoma 1; K06618 retinoblastoma-associated protein (A)	Cell cycle (ko04110);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Pancreatic cancer (ko05212);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Retinoblastoma-associated protein A domain;; Rb C-terminal domain;; Retinoblastoma-associated protein B domain;; Domain of unknown function (DUF3452)	Retinoblastoma-associated protein GN=RB1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: retinoblastoma-associated protein [Galeopterus variegatus]
ENSG00000139697(SBNO1)	--	20.92395221	2556	23.60811954	2780	23.35427678	2766	20.98586521	2529	18.106054	2318	20.89394484	2546	0.988479191	-0.046125189	normal	0.947541991	-0.283461738	normal	0.985165654	-0.127787333	normal	0.436464399	-0.15327846	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[KT]	Transcription;; Signal transduction mechanisms	"P-loop containing NTP hydrolase pore-1;; Helicase_C-like;; Type III restriction enzyme, res subunit"	Protein strawberry notch homolog 1 GN=SBNO1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein strawberry notch homolog 1 isoform X4 [Equus przewalskii]
ENSG00000139714(MORN3)	--	0.298748551	22	0.265319889	20	0.170676374	12	0.120643628	9	0.118865125	8	0.093788475	7	0.898869421	-1.187084963	normal	0.913015249	-1.196267544	normal	--	--	--	--	--	--	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat	MORN repeat-containing protein 3 GN=MORN3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	MORN repeat-containing protein 3 [Sus scrofa]
ENSG00000139718(SETD1B)	--	4.128915032	723	5.1968852	859	4.517191581	756	4.919397201	835	5.065690756	886	5.6114189	997	0.960190547	0.176598866	normal	0.977253865	0.023181825	normal	0.744986492	0.390234003	normal	0.339814618	0.196498739	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	"K11422|0|hsa:23067|SETD1B, KMT2G, Set1B; SET domain containing 1B (EC:2.1.1.43); K11422 histone-lysine N-methyltransferase SETD1 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[BK]	Chromatin structure and dynamics;; Transcription	"COMPASS (Complex proteins associated with Set1p) component N;; SET domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Histone-lysine N-methyltransferase SETD1B GN=SETD1B OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: histone-lysine N-methyltransferase SETD1B [Sus scrofa]
ENSG00000139719(VPS33A)	--	9.973674384	821	14.170633	930	10.30794307	816	11.894217	891	11.57496477	935	12.65249884	1044	0.974569284	0.087054542	normal	0.978187494	-0.013668742	normal	0.839785386	0.34661992	normal	0.531347473	0.140103387	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec1 family	Vacuolar protein sorting-associated protein 33A GN=VPS33A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 33A isoform X1 [Camelus ferus] 
ENSG00000139722(VPS37B)	--	14.736657	698	12.3841013	587	13.65316706	663	17.81230132	868	18.13400096	859	15.1772465	752	0.910902488	0.283076096	normal	0.273106335	0.526743053	normal	0.959747763	0.173061474	normal	0.075770234	0.326272931	normal	--	--	--	K12185|3.94013e-117|hsa:79720|VPS37B; vacuolar protein sorting 37 homolog B (S. cerevisiae); K12185 ESCRT-I complex subunit VPS37 (A)	Endocytosis (ko04144)	[S]	Function unknown	Modifier of rudimentary (Mod(r)) protein	Vacuolar protein sorting-associated protein 37B GN=VPS37B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 37B [Odobenus rosmarus divergens]
ENSG00000139725(RHOF)	--	50.4848284	2317	49.00016024	2213	57.25807122	2693	64.75516939	3029	47.35336067	2117	49.3569233	2296	0.877759477	0.355544551	normal	0.98535682	-0.0853491	normal	0.965617711	-0.238237975	normal	0.963648318	0.021222223	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07872|3.04898e-138|hsa:54509|RHOF, ARHF, RIF; ras homolog family member F (in filopodia); K07872 Ras homolog gene family, member F (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoF (Precursor) GN=RHOF OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoF [Camelus bactrianus] 
ENSG00000139726(DENR)	--	46.52081628	1970	48.64920907	2078	45.64951027	1913	55.67342643	2394	49.60491071	2095	51.26381221	2170	0.958093119	0.250218016	normal	0.9869017	-0.009664963	normal	0.976726343	0.173437916	normal	0.497383076	0.138104897	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	--	--	[R]	General function prediction only	Translation initiation factor SUI1	Density-regulated protein GN=DENR OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: density-regulated protein isoform X1 [Tupaia chinensis] 
ENSG00000139734(DIAPH3)	--	8.433419738	760	9.082829027	818	9.628872508	870	9.765862423	905	7.052542267	656	7.795299455	711	0.947809594	0.220676895	normal	0.850068473	-0.339129872	normal	0.897567455	-0.29888156	normal	0.613538258	-0.129545426	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	"K05745|0|hsa:81624|DIAPH3, AN, AUNA1, DIA2, DRF3, NSDAN, diap3, mDia2; diaphanous-related formin 3; K05745 diaphanous 3 (A)"	Regulation of actin cytoskeleton (ko04810)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain;; TPR/MLP1/MLP2-like protein;; DRF Autoregulatory Domain	Protein diaphanous homolog 3 GN=DIAPH3 OS=Homo sapiens (Human) PE=1 SV=4	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: protein diaphanous homolog 3 isoform X1 [Equus caballus]
ENSG00000139737(SLAIN1)	--	3.343190861	155	4.794626732	163	4.364493933	138	2.28978816	106	2.622431862	121	2.441132269	92	0.612807649	-0.57213346	normal	0.816478575	-0.44646472	normal	0.640651973	-0.585343794	normal	0.124274986	-0.537219596	normal	--	--	--	"K16580|0|pale:102891615|SLAIN1; SLAIN motif family, member 1; K16580 SLAIN motif-containing protein 1/2 (A)"	--	--	--	SLAIN motif-containing family	SLAIN motif-containing protein 1 GN=SLAIN1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: SLAIN motif-containing protein 1 [Pteropus alecto]
ENSG00000139746(RBM26)	--	11.47626388	1304	11.3095533	1278	13.31979369	1381	10.70684701	1190	9.397646618	1089	9.544003816	1096	0.970741138	-0.162613892	normal	0.941975689	-0.251987015	normal	0.858483962	-0.341336405	normal	0.152032823	-0.253043194	normal	--	--	Biological Process: mRNA processing (GO:0006397);; 	K13192|0|chx:102187238|RBM26; RNA binding motif protein 26; K13192 RNA-binding protein 26 (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Nup53/35/40-type RNA recognition motif;; PWI domain"	RNA-binding protein 26 GN=RBM26 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: RNA-binding protein 26 isoform X6 [Equus przewalskii]
ENSG00000139767(SRRM4)	--	0	0	0	0	0	0	0.00584327	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Serine/arginine repetitive matrix protein C-terminus	Serine/arginine repetitive matrix protein 4 GN=SRRM4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: serine/arginine repetitive matrix protein 4 [Pteropus alecto]
ENSG00000139793(MBNL2)	--	15.150771	1102	18.84259874	1338	21.7824856	1528	12.36862847	902	9.011874761	658	18.44297603	1348	0.880821698	-0.319264152	normal	2.86E-07	-1.043626266	down	0.96800482	-0.188916281	normal	0.294294285	-0.468024362	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K14943|0|ptr:467304|MBNL2; muscleblind-like splicing regulator 2; K14943 muscleblind (A)	--	[K]	Transcription	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Muscleblind-like protein 2 GN=MBNL2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: muscleblind-like protein 2 isoform X1 [Orycteropus afer afer]
ENSG00000139800(ZIC5)	--	2.208997939	165	2.625752058	175	1.906617803	149	3.120327371	229	2.881145762	233	3.352641263	242	0.769885668	0.438569531	normal	0.836875195	0.388629208	normal	0.135869453	0.685889256	normal	0.075188336	0.504476933	normal	[R]	General function prediction only	--	K09226|2.23251e-175|ggo:101125775|ZIC5; zinc finger protein ZIC 5; K09226 zinc finger protein ZIC 5 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein ZIC 5 GN=ZIC5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein ZIC 5 [Equus przewalskii]
ENSG00000139826(ABHD13)	--	5.90227	422	6.3811	456	5.03396	351	4.41906	320	5.01908	358	4.34295	310	0.685028468	-0.428206486	normal	0.809519296	-0.36911549	normal	0.949483784	-0.186638006	normal	0.154002984	-0.336516122	normal	[R]	General function prediction only	--	K06889|0|ptr:467322|ABHD13; abhydrolase domain containing 13; K06889 (A)	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Acetyl xylan esterase (AXE1);; Phospholipase/Carboxylesterase;; alpha/beta hydrolase fold	Alpha/beta hydrolase domain-containing protein 13 GN=ABHD13 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: alpha/beta hydrolase domain-containing protein 13 [Orcinus orca] 
ENSG00000139832(RAB20)	--	0.856776	25	0.556556	17	0.54686	16	1.20783	36	2.00473	58	1.31366	39	0.969524193	0.471007805	normal	0.004904198	1.664425335	up	0.538029495	1.202213308	normal	0.032153385	1.176177778	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07911|9.84908e-176|pps:100977562|RAB20; RAB20, member RAS oncogene family; K07911 Ras-related protein Rab-20 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-20 GN=RAB20 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-20 [Dasypus novemcinctus]
ENSG00000139835(GRTP1)	--	4.01142	111	2.8640354	77	3.511943282	94	2.9618561	80	3.158372663	87	3.107040645	80	0.842224422	-0.495206478	normal	0.96696891	0.151922122	normal	0.959083502	-0.236817676	normal	0.704388365	-0.212250457	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	Growth hormone-regulated TBC protein 1 GN=GRTP1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: growth hormone-regulated TBC protein 1 [Eptesicus fuscus]
ENSG00000139842(CUL4A)	--	31.87450106	1808	31.56761151	1834	31.69908802	1858	31.22832094	1808	30.232346	1724	31.60816199	1833	0.985663491	-0.030806085	normal	0.981643651	-0.110566367	normal	0.985929055	-0.027812366	normal	0.822849126	-0.056989017	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	K10609|0|ptr:452694|CUL4A; cullin 4A; K10609 cullin 4 (A)	Nucleotide excision repair (ko03420);; Ubiquitin mediated proteolysis (ko04120)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cullin family;; Cullin protein neddylation domain	Cullin-4A GN=CUL4A OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cullin-4A [Pteropus alecto]
ENSG00000139865(TTC6)	--	0.054579809	6	0.072968428	8	0.113406867	12	0.174488617	20	0.237367993	27	0.979889059	29	--	--	--	0.501665645	1.564565049	normal	0.803733772	1.167496426	normal	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Tetratricopeptide repeat protein 6 GN=TTC6 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: uncharacterized protein LOC101686827 isoform X2 [Mustela putorius furo]
ENSG00000139874(SSTR1)	--	0	0	0	0	0	0	0.0318744	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04217|0|phd:102337755|SSTR1; somatostatin receptor 1; K04217 somatostatin receptor 1 (A)	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srx	Somatostatin receptor type 1 GN=SSTR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: somatostatin receptor type 1, partial [Pantholops hodgsonii]"
ENSG00000139880(CDH24)	--	4.390188844	307	3.635260687	266	3.487098458	227	5.625308708	413	5.648593137	402	3.780273034	278	0.766439297	0.395359633	normal	0.256425355	0.571681598	normal	0.914898621	0.282398386	normal	0.169542323	0.427614539	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06814|0|hsa:64403|CDH24, CDH11L; cadherin 24, type 2; K06814 cadherin-like 24 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin-like	Cadherin-24 (Precursor) GN=CDH24 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cadherin-24 [Loxodonta africana]
ENSG00000139890(REM2)	--	0.372967211	13	0.277553845	10	0.244807127	8	0.437570238	16	0.383640019	13	0.262133567	8	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07848|0|hsa:161253|REM2; RAS (RAD and GEM)-like GTP binding 2; K07848 Rad and Gem related GTP binding protein 2 (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein	GTP-binding protein REM 2 GN=REM2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: GTP-binding protein REM 2 [Eptesicus fuscus]
ENSG00000139899(CBLN3)	--	1.22486	58	1.133691	51	1.403317	65	0.713618	27	1.340758	37	1.077359	39	0.292095303	-1.090571141	normal	0.948050662	-0.468033583	normal	0.778335388	-0.723303756	normal	0.134642319	-0.776152686	normal	--	--	--	--	--	--	--	C1q domain	Cerebellin-3 (Precursor) GN=CBLN3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cerebellin-3 [Orycteropus afer afer]
ENSG00000139908(TSSK4)	--	0.962260303	20	1.105476447	21	0.9871455	18	0.73295074	17	1.860062	27	1.069321426	25	0.988356403	-0.244869992	normal	0.98204812	0.320732491	normal	0.98118188	0.434544571	normal	0.851635345	0.205650827	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08811|0|hsa:283629|TSSK4, C14orf20, STK22E, TSK-4, TSK4, TSSK5; testis-specific serine kinase 4 (EC:2.7.11.1); K08811 testis-specific serine kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Testis-specific serine/threonine-protein kinase 4 GN=TSSK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: testis-specific serine/threonine-protein kinase 4 isoform 1 [Ceratotherium simum simum]
ENSG00000139910(NOVA1)	--	15.10510886	415	18.462368	521	20.29957187	512	11.99513123	356	14.64228667	456	11.73078444	391	0.925769189	-0.251061555	normal	0.942812807	-0.213014612	normal	0.747544874	-0.39592424	normal	0.205321542	-0.288123437	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K14944|0|hsa:4857|NOVA1, Nova-1; neuro-oncological ventral antigen 1; K14944 RNA-binding protein Nova (A)"	--	[AR]	RNA processing and modification;; General function prediction only	KH domain;; KH domain;; KH domain;; KH domain	RNA-binding protein Nova-1 GN=NOVA1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein Nova-1 [Camelus bactrianus]
ENSG00000139915(MDGA2)	--	0	0	0	0	0	0	0.11824818	6	0.287515242	14	0.215535163	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; MAM domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	MAM domain-containing glycosylphosphatidylinositol anchor protein 2 (Precursor) GN=MDGA2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: MAM domain-containing glycosylphosphatidylinositol anchor protein 2 isoform X1 [Vicugna pacos]
ENSG00000139921(TMX1)	--	36.3277014	1912	39.471695	2066	36.1672079	1854	38.95670247	2077	36.87211212	1942	34.95300127	1841	0.984660832	0.088518173	normal	0.983034545	-0.11064006	normal	0.986057595	-0.018427975	normal	0.966005434	-0.014789068	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Thioredoxin	Thioredoxin-related transmembrane protein 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin-related transmembrane protein 1 [Orycteropus afer afer]
ENSG00000139926(FRMD6)	--	6.071529094	459	7.053536493	489	7.857124642	565	21.93056371	1573	17.62078554	1302	14.980025	980	0	1.74277405	up	5.61E-13	1.388661896	up	0.00101738	0.784625092	normal	3.01E-05	1.327043899	up	--	--	--	K16822|0|ptr:467455|FRMD6; FERM domain containing 6; K16822 FERM domain-containing protein 6 (A)	Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	FERM central domain;; FERM C-terminal PH-like domain;; FERM N-terminal domain	FERM domain-containing protein 6 GN=FRMD6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: FERM domain-containing protein 6 isoform X1 [Galeopterus variegatus]
ENSG00000139946(PELI2)	--	2.53571553	167	2.66891512	89	1.247201452	111	3.177980861	188	3.503779906	213	3.7209337	254	0.959941519	0.138847893	normal	3.22E-05	1.223702674	up	1.88E-05	1.175098915	up	0.013513237	0.815320546	normal	--	--	Biological Process: Toll signaling pathway (GO:0008063);; 	K11964|0|hsa:57161|PELI2; pellino E3 ubiquitin protein ligase family member 2; K11964 pellino (A)	--	[T]	Signal transduction mechanisms	Pellino	E3 ubiquitin-protein ligase pellino homolog 2 GN=PELI2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: E3 ubiquitin-protein ligase pellino homolog 2-like isoform X1 [Tupaia chinensis]
ENSG00000139970(RTN1)	--	0.018617793	1	0.037493874	2	0.132421855	2	0.03715805	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Reticulon	Reticulon-1 GN=RTN1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: reticulon-1 isoform X1 [Eptesicus fuscus]
ENSG00000139971(C14orf37)	--	0.0807654	6	0.020371331	1	0.0159328	1	0.2449908	25	0.396293928	24	0.202582492	14	0.391896013	1.789220534	normal	0.002757646	3.329789018	up	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C14orf37 (Precursor) GN=C14orf37 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C14orf37 homolog [Equus przewalskii]
ENSG00000139973(SYT16)	--	0.259635235	47	0.600997474	80	0.336784093	37	0.296379444	21	0.226518419	42	0.235880731	43	0.429136878	-1.136100865	normal	0.283431423	-0.926450144	normal	0.978268984	0.200897022	normal	0.402102147	-0.649768091	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-16 GN=SYT16 OS=Homo sapiens (Human) PE=2 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-16 [Pteropus alecto]
ENSG00000139977(NAA30)	--	19.33929192	785	19.71361093	865	19.9309306	824	21.14709373	932	21.2625525	903	19.93131751	864	0.949993435	0.216415942	normal	0.976978382	0.040529945	normal	0.976202742	0.059988008	normal	0.668074155	0.104144177	normal	[R]	General function prediction only	"Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	"K00670|0|hsa:122830|NAA30, C14orf35, MAK3, Mak3p, NAT12, NAT12P; N(alpha)-acetyltransferase 30, NatC catalytic subunit (EC:2.3.1.88); K00670 peptide alpha-N-acetyltransferase [EC:2.3.1.88] (A)"	--	[R]	General function prediction only	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; FR47-like protein;; Acetyltransferase (GNAT) domain	N-alpha-acetyltransferase 30 GN=NAA30 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: N-alpha-acetyltransferase 30 [Bos mutus]
ENSG00000139985(ADAM21)	--	0.0875018	4	0.0649248	3	0	0	0.0655579	3	0.0426973	1	0.0656504	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08610|0|hsa:8747|ADAM21, ADAM_21, ADAM31; ADAM metallopeptidase domain 21; K08610 disintegrin and metalloproteinase domain-containing protein 21 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Reprolysin family propeptide;; Disintegrin;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 21 (Precursor) GN=ADAM21 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: disintegrin and metalloproteinase domain-containing protein 21-like [Galeopterus variegatus]
ENSG00000139988(RDH12)	--	0	0	0.060847199	2	0.029825608	0	0	0	0.060825647	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K11153|0|ptr:100615509|RDH12; retinol dehydrogenase 12 (all-trans/9-cis/11-cis); K11153 retinol dehydrogenase 12 [EC:1.1.1.300] (A)	Retinol metabolism (ko00830)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; NAD dependent epimerase/dehydratase family	Retinol dehydrogenase 12 GN=RDH12 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: retinol dehydrogenase 12 isoform X1 [Tupaia chinensis] 
ENSG00000139990(DCAF5)	--	11.94986413	1090	10.89892228	1004	11.49892287	1018	12.69459923	1220	14.66877461	1388	11.54217743	1102	0.974159912	0.131545428	normal	0.584804512	0.445249094	normal	0.975835147	0.105943919	normal	0.203538362	0.232159719	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	K11800|0|pps:100967825|DCAF5; DDB1 and CUL4 associated factor 5; K11800 WD repeat-containing protein 22 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 5 GN=DCAF5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 5 [Galeopterus variegatus]
ENSG00000139998(RAB15)	--	6.562835	467	7.913227008	574	7.852456	568	16.79506	1188	17.776241	1182	16.360377	1157	9.68E-12	1.313404433	up	9.79E-07	1.018771328	up	7.02E-07	1.016199448	up	2.04E-14	1.11113276	up	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07908|3.70134e-146|mmu:104886|Rab15, 2310012G06Rik, AI840042; RAB15, member RAS oncogene family; K07908 Ras-related protein Rab-15 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase	Ras-related protein Rab-15 GN=RAB15 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-15 [Ceratotherium simum simum]
ENSG00000140006(WDR89)	--	6.9932769	309	7.9930033	335	7.061476717	302	9.422629191	372	8.3780361	367	7.361151864	314	0.933216701	0.235793807	normal	0.962157333	0.10971909	normal	0.967035503	0.047690352	normal	0.679563542	0.132807025	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 89 GN=WDR89 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 89 isoform X2 [Galeopterus variegatus]
ENSG00000140009(ESR2)	--	0.1517627	10	0.0993066	10	0.0771632	6	0.1203324	10	0.097311	8	0.1723386	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K08551|0|ggo:101142471|ESR2; estrogen receptor beta isoform 1; K08551 estrogen receptor beta (A)	Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Estrogen receptor beta;; Zinc finger, C4 type (two domains)"	Estrogen receptor beta GN=ESR2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: estrogen receptor beta isoform X1 [Ursus maritimus]
ENSG00000140015(KCNH5)	--	0	0	0	0	0.098459218	4	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	"Molecular Function: ion channel activity (GO:0005216);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; "	"K04908|0|hsa:27133|KCNH5, EAG2, H-EAG2, Kv10.2, hEAG2; potassium voltage-gated channel, subfamily H (eag-related), member 5; K04908 potassium voltage-gated channel Eag-related subfamily H member 5 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; PAS domain;; Ion channel;; Cyclic nucleotide-binding domain;; PAS fold	Potassium voltage-gated channel subfamily H member 5 GN=KCNH5 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily H member 5 isoform X1 [Loxodonta africana]
ENSG00000140022(STON2)	--	0.934476112	94	1.037600448	119	1.047606346	116	2.9347121	216	2.295525161	227	2.258075161	255	9.30E-05	1.156658287	up	0.007443337	0.901870259	normal	6.08E-05	1.118002662	up	5.45E-05	1.064555974	up	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Stonin 2;; Adaptor complexes medium subunit family	Stonin-2 GN=STON2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: stonin-2 [Ceratotherium simum simum]
ENSG00000140025(EFCAB11)	--	8.86237455	177	5.622938517	141	9.941387442	186	7.738126031	172	7.197794044	169	7.882770825	178	0.965499511	-0.071543026	normal	0.942665747	0.23757153	normal	0.965340322	-0.071125619	normal	0.977062776	0.021547574	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair;; EF hand	EF-hand calcium-binding domain-containing protein 11 GN=EFCAB11 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: EF-hand calcium-binding domain-containing protein 11 [Leptonychotes weddellii]
ENSG00000140030(GPR65)	--	0	0	0	0	0	0	0	0	0	0	0.0151281	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08416|0|hsa:8477|GPR65, TDAG8, hTDAG8; G protein-coupled receptor 65; K08416 G protein-coupled receptor 65 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Psychosine receptor GN=GPR65 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: psychosine receptor [Galeopterus variegatus]
ENSG00000140044(JDP2)	--	21.194019	524	37.32616163	836	29.56464307	760	21.16121573	467	20.6855286	470	47.62609029	974	0.948856548	-0.196366174	normal	0.000300764	-0.850187839	normal	0.833929964	0.349015947	normal	0.845881627	-0.168576622	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09033|3.37518e-95|pon:100431566|JDP2; Jun dimerization protein 2; K09033 jun dimerization protein 2 (A)	--	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Jun dimerization protein 2 GN=JDP2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: jun dimerization protein 2 isoform X1 [Bubalus bubalis]
ENSG00000140057(AK7)	--	6.300213	362	4.87404019	246	5.240250997	299	2.61652	128	2.716676644	156	2.567321	141	8.75E-11	-1.519325968	down	0.155403414	-0.673294008	normal	4.32E-05	-1.084564248	down	2.18E-05	-1.114417466	down	--	--	--	"K00939|0|hsa:122481|AK7, AK_7; adenylate kinase 7 (EC:2.7.4.3 2.7.4.6); K00939 adenylate kinase [EC:2.7.4.3] (A)"	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	Dpy-30 motif;; Adenylate kinase;; AAA domain;; AAA domain	Adenylate kinase 7 GN=AK7 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: adenylate kinase 7 [Leptonychotes weddellii]
ENSG00000140090(SLC24A4)	--	0.18107847	19	0.038074187	3	1.823070363	11	0.081440047	14	0.086962972	6	0.919788469	5	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13752|0|hsa:123041|SLC24A4, AI2A5, NCKX4, SHEP6, SLC24A2; solute carrier family 24 (sodium/potassium/calcium exchanger), member 4; K13752 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Sodium/calcium exchanger protein	Sodium/potassium/calcium exchanger 4 (Precursor) GN=SLC24A4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium/calcium exchanger 4 isoform 1 [Ceratotherium simum simum]
ENSG00000140092(FBLN5)	--	2.540087681	131	3.508389886	134	2.33018327	116	1.321088974	67	2.279077133	117	2.244806179	116	0.024313361	-0.981753498	normal	0.952096791	-0.21455732	normal	0.969509408	-0.008184738	normal	0.379994636	-0.364627305	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K17340|0|ptr:453112|FBLN5; fibulin 5; K17340 fibulin 5 (A)	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Coagulation Factor Xa inhibitory site;; EGF domain	Fibulin-5 (Precursor) GN=FBLN5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	thyroid receptor-interacting protein 11-like protein [Camelus ferus]
ENSG00000140093(SERPINA10)	--	0.068983158	6	0	0	0.02302685	1	0.01143963	1	0.033415631	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Protein Z-dependent protease inhibitor (Precursor) GN=SERPINA10 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: protein Z-dependent protease inhibitor isoform 1 [Dasypus novemcinctus] 
ENSG00000140104(C14orf79)	--	5.245061295	305	5.1696383	307	5.28950844	322	7.080430095	372	5.505954237	322	5.990688714	351	0.924705242	0.254498785	normal	0.966155854	0.047168594	normal	0.962228062	0.11559876	normal	0.658860259	0.140673878	normal	--	--	--	--	--	--	--	"Clathrin-binding box of Aftiphilin, vesicle trafficking"	Uncharacterized protein C14orf79 GN=C14orf79 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C14orf79 homolog isoform X3 [Equus przewalskii]
ENSG00000140105(WARS)	--	39.8282127	1686	41.3251871	1700	43.28424718	1718	50.49106613	2058	43.99459945	1783	47.63628186	2035	0.9512997	0.256594263	normal	0.984556789	0.047304308	normal	0.960001711	0.235816376	normal	0.334108186	0.181943229	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	K01867|0|pps:100981300|WARS; tryptophanyl-tRNA synthetase; K01867 tryptophanyl-tRNA synthetase [EC:6.1.1.2] (A)	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class I (W and Y);; WHEP-TRS domain	T2-TrpRS GN=WARS OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tryptophan--tRNA ligase, cytoplasmic [Elephantulus edwardii]"
ENSG00000140153(WDR20)	--	12.48515185	451	12.17177845	508	15.5955202	551	14.25429745	516	12.99442187	486	10.39689014	442	0.95711812	0.162892306	normal	0.967649012	-0.085039885	normal	0.865175948	-0.325298433	normal	0.780259177	-0.085894498	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 20 GN=WDR20 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 20 isoform 1 [Trichechus manatus latirostris]
ENSG00000140157(NIPA2)	--	60.61182	1807	59.03842	1807	62.98533	1906	71.19642	2135	63.23841001	1839	63.05981	1920	0.968826387	0.209643171	normal	0.985642143	0.003895184	normal	0.986476002	0.002264959	normal	0.758998567	0.073108338	normal	--	--	Molecular Function: magnesium ion transmembrane transporter activity (GO:0015095);; Biological Process: magnesium ion transport (GO:0015693);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Magnesium transporter NIPA;; Multidrug resistance efflux transporter;; EamA-like transporter family	Magnesium transporter NIPA2 GN=NIPA2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: magnesium transporter NIPA2 isoform X1 [Leptonychotes weddellii]
ENSG00000140199(SLC12A6)	--	8.634188993	862	8.561278607	880	6.635534381	822	5.382606491	739	5.196741619	706	6.450758175	864	0.932117091	-0.252459169	normal	0.85217342	-0.338610755	normal	0.976008223	0.06348754	normal	0.422855972	-0.171985255	normal	[E]	Amino acid transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14427|0|ggo:101142838|SLC12A6; solute carrier family 12 member 6 isoform 1; K14427 solute carrier family 12 (potassium/chloride transporter), member 4/5/6 (A)"	--	[P]	Inorganic ion transport and metabolism	Amino acid permease;; K-Cl Co-transporter type 1 (KCC1);; Amino acid permease	Solute carrier family 12 member 6 GN=SLC12A6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 12 member 6 isoform X1 [Leptonychotes weddellii]
ENSG00000140254(DUOXA1)	--	0.418780073	9	0.69944329	13	0.125662	5	0.2031027	8	0.417267272	11	0.242665196	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of membrane (GO:0016021);; 	"K17233|0|hsa:90527|DUOXA1, NIP, NUMBIP, mol; dual oxidase maturation factor 1; K17233 dual oxidase maturation factor 1 (A)"	--	[S]	Function unknown	Dual oxidase maturation factor	Dual oxidase maturation factor 1 GN=DUOXA1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: dual oxidase maturation factor 1 isoform X1 [Galeopterus variegatus]
ENSG00000140259(MFAP1)	--	16.131	783	15.8045	777	15.7453	766	15.485	759	15.7157	758	15.1813	734	0.974099213	-0.075594012	normal	0.97459061	-0.057030921	normal	0.974235301	-0.069715154	normal	0.80579017	-0.06859448	normal	--	--	--	K13110|7.42887e-172|cge:100753487|Mfap1; microfibrillar-associated protein 1; K13110 microfibrillar-associated protein 1 (A)	--	[Z]	Cytoskeleton	"Splicing factor, Prp19-binding domain"	Microfibrillar-associated protein 1 GN=MFAP1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: microfibrillar-associated protein 1 [Sorex araneus] 
ENSG00000140262(TCF12)	--	21.91647901	1823	22.24564499	1950	22.76303808	1872	20.32549587	1822	22.22152035	1948	24.42325589	2004	0.985728133	-0.031597228	normal	0.986153548	-0.022889244	normal	0.984302098	0.089940396	normal	0.973900077	0.011682957	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K15603|0|mcf:101926020|uncharacterized LOC101926020; K15603 transcription factor 4/12 (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Transcription factor 12 GN=TCF12 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor 12 isoform X1 [Condylura cristata] 
ENSG00000140263(SORD)	--	20.24976285	1085	17.84020807	998	19.50892715	1033	20.34572136	1127	23.0920275	1232	12.0062167	658	0.980501103	0.023926965	normal	0.921942896	0.282078664	normal	0.020637517	-0.657755212	normal	0.902702768	-0.069019669	normal	[ER]	Amino acid transport and metabolism;; General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	"K00008|0|hsa:6652|SORD, HEL-S-95n, SORD1; sorbitol dehydrogenase (EC:1.1.1.14); K00008 L-iditol 2-dehydrogenase [EC:1.1.1.14] (A)"	Pentose and glucuronate interconversions (ko00040);; Fructose and mannose metabolism (ko00051)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	Sorbitol dehydrogenase GN=SORD OS=Homo sapiens (Human) PE=1 SV=4	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: sorbitol dehydrogenase [Galeopterus variegatus]
ENSG00000140264(SERF2)	--	220.031127	3387	232.463581	3914	220.1250683	3694	204.7483274	3288	206.379576	3160	225.6322111	3598	0.989949586	-0.073596065	normal	0.927071981	-0.330003544	normal	0.991192509	-0.046260931	normal	0.451575207	-0.151179151	normal	--	--	--	--	--	--	--	4F5 protein family	Small EDRK-rich factor 2 GN=SERF2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: small EDRK-rich factor 2 isoform 1 [Tursiops truncatus]
ENSG00000140265(ZSCAN29)	--	5.559423399	663	6.07615236	671	5.281202499	633	4.553658099	566	6.1009549	681	6.353670469	666	0.924228354	-0.258390157	normal	0.974424928	-8.43E-05	normal	0.972811409	0.064874122	normal	0.837459499	-0.060910204	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:146050|ZSCAN29, ZNF690, Zfp690; zinc finger and SCAN domain containing 29; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Myb/SANT-like DNA-binding domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Alcohol dehydrogenase transcription factor Myb/SANT-like"	Zinc finger and SCAN domain-containing protein 29 GN=ZSCAN29 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 29 [Pteropus alecto]
ENSG00000140274(DUOXA2)	--	0.0417395	1	0	0	0	0	0.0414931	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of membrane (GO:0016021);; 	"K17232|0|hsa:405753|DUOXA2, SIMNIPHOM, TDH5; dual oxidase maturation factor 2; K17232 dual oxidase maturation factor 2 (A)"	Thyroid hormone synthesis (ko04918)	[S]	Function unknown	Dual oxidase maturation factor	Dual oxidase maturation factor 2 GN=DUOXA2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: dual oxidase maturation factor 2 [Camelus ferus] 
ENSG00000140279(DUOX2)	--	0.0607104	8	0.085679792	11	0.022925817	2	0.06323497	8	0.082343395	10	0.031248165	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13411|0|hsa:50506|DUOX2, LNOX2, NOXEF2, P138-TOX, TDH6, THOX2; dual oxidase 2 (EC:1.6.3.1); K13411 dual oxidase [EC:1.6.3.1 1.11.1.-] (A)"	Thyroid hormone synthesis (ko04918)	[PQ]	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Animal haem peroxidase;; Ferric reductase NAD binding domain;; FAD-binding domain;; Ferric reductase like transmembrane component;; EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand;; Oxidoreductase NAD-binding domain	Dual oxidase 2 (Precursor) GN=DUOX2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual oxidase 2 [Galeopterus variegatus]
ENSG00000140280(LYSMD2)	--	12.960857	307	12.950156	314	12.254311	296	9.814219	240	10.00406	235	9.52027	220	0.812366673	-0.383857412	normal	0.714049695	-0.437087758	normal	0.729469021	-0.43380459	normal	0.097156012	-0.42143609	normal	[M]	Cell wall/membrane/envelope biogenesis	--	--	--	--	--	LysM domain	LysM and putative peptidoglycan-binding domain-containing protein 2 GN=LYSMD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 2 [Odobenus rosmarus divergens]
ENSG00000140284(SLC27A2)	--	38.50083	1604	29.3652185	1236	37.065755	1551	33.3005506	1403	38.629546	1595	38.156396	1586	0.959110008	-0.223761997	normal	0.861648649	0.346077488	normal	0.984367207	0.023879617	normal	0.886719891	0.041484522	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K08746|0|pps:100968109|SLC27A2; solute carrier family 27 (fatty acid transporter), member 2; K08746 solute carrier family 27 (fatty acid transporter), member 2 [EC:6.2.1.- 6.2.1.3] (A)"	PPAR signaling pathway (ko03320);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	Very long-chain acyl-CoA synthetase GN=SLC27A2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: very long-chain acyl-CoA synthetase isoform X1 [Orycteropus afer afer]
ENSG00000140285(FGF7)	--	0.119953	7	0.034564	2	0.225388	12	0.0675817	4	0.279707	18	0.118205	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|5.98355e-145|ptr:744975|FGF7; fibroblast growth factor 7; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 7 (Precursor) GN=FGF7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 7 [Tupaia chinensis]
ENSG00000140287(HDC)	--	0.1045204	5	0.023664666	1	0	0	0.024007985	1	0.0795788	3	0.023806819	1	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: carboxy-lyase activity (GO:0016831);; Biological Process: carboxylic acid metabolic process (GO:0019752);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	K01590|0|hsa:3067|HDC; histidine decarboxylase (EC:4.1.1.22); K01590 histidine decarboxylase [EC:4.1.1.22] (A)	Histidine metabolism (ko00340)	[E]	Amino acid transport and metabolism	Pyridoxal-dependent decarboxylase conserved domain;; Beta-eliminating lyase	Histidine decarboxylase GN=HDC OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: histidine decarboxylase [Canis lupus familiaris]
ENSG00000140297(GCNT3)	--	46.561016	2364	56.95837337	3003	47.58480715	2412	76.1099	3912	74.30474001	3718	99.4224236	5071	0.005794921	0.695489285	normal	0.954363374	0.286565832	normal	1.54E-08	1.063278674	up	0.005923048	0.686607177	normal	--	--	Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; 	"K09662|0|hsa:9245|GCNT3, C2/4GnT, C24GNT, C2GNT2, C2GNTM, GNTM; glucosaminyl (N-acetyl) transferase 3, mucin type (EC:2.4.1.102 2.4.1.150); K09662 N-acetylglucosaminyltransferase 3, mucin type [EC:2.4.1.-] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	Core-2/I-Branching enzyme	"Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 GN=GCNT3 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3 [Trichechus manatus latirostris]"
ENSG00000140299(BNIP2)	--	33.382096	1622	36.0547495	1792	33.06061995	1612	37.21959339	1811	33.33267284	1670	32.16407749	1598	0.979977825	0.128065623	normal	0.980268189	-0.123041501	normal	0.984643303	-0.020856126	normal	0.986272296	-0.006568157	normal	--	--	--	"K18448|0|hsa:663|BNIP2, BNIP-2, NIP2; BCL2/adenovirus E1B 19kDa interacting protein 2; K18448 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (A)"	--	--	--	Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2;; Divergent CRAL/TRIO domain;; CRAL/TRIO domain	BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 GN=BNIP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 [Trichechus manatus latirostris]
ENSG00000140307(GTF2A2)	--	73.858882	1260	57.55716608	1247	72.225374	1331	74.150466	1282	60.78904	1189	67.506997	1235	0.982255013	-0.00585266	normal	0.978453214	-0.090027481	normal	0.977397282	-0.116153927	normal	0.773660129	-0.07171011	normal	[K]	Transcription	Cellular Component: transcription factor TFIIA complex (GO:0005672);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	"K03123|5.15445e-74|ptr:453483|GTF2A2; general transcription factor IIA, 2, 12kDa; K03123 transcription initiation factor TFIIA small subunit (A)"	Basal transcription factors (ko03022);; Viral carcinogenesis (ko05203)	[K]	Transcription	"Transcription initiation factor IIA, gamma subunit;; Transcription initiation factor IIA, gamma subunit, helical domain"	Transcription initiation factor IIA subunit 2 GN=GTF2A2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor IIA subunit 2 [Ochotona princeps]
ENSG00000140319(SRP14)	--	108.0080118	1795	102.9567147	1726	103.9870072	1746	117.8520224	1978	119.233408	1976	118.0538342	1978	0.98274949	0.10913731	normal	0.974962589	0.1735817	normal	0.975626395	0.171557736	normal	0.451500224	0.150345534	normal	--	--	"Cellular Component: signal recognition particle, endoplasmic reticulum targeting (GO:0005786);; Biological Process: SRP-dependent cotranslational protein targeting to membrane (GO:0006614);; Molecular Function: 7S RNA binding (GO:0008312);; Molecular Function: endoplasmic reticulum signal peptide binding (GO:0030942);; "	K03104|1.57863e-70|cjc:100388844|SRP14; signal recognition particle 14kDa (homologous Alu RNA binding protein); K03104 signal recognition particle subunit SRP14 (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Signal recognition particle 14kD protein	Signal recognition particle 14 kDa protein GN=SRP14 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle 14 kDa protein [Tupaia chinensis]
ENSG00000140320(BAHD1)	--	5.769073791	551	5.184819922	503	5.825645114	569	6.663776827	624	5.311677819	505	4.947492626	476	0.962143264	0.148272772	normal	0.971026839	-0.015654598	normal	0.918861159	-0.264987424	normal	0.912431504	-0.038004109	normal	--	--	Molecular Function: chromatin binding (GO:0003682);; 	--	--	[K]	Transcription	BAH domain	Bromo adjacent homology domain-containing 1 protein GN=BAHD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: bromo adjacent homology domain-containing 1 protein isoform 1 [Dasypus novemcinctus]
ENSG00000140323(DISP2)	--	0.355638541	88	0.247184903	62	0.373671653	93	0.148875868	37	0.124731717	31	0.1908969	48	0.010505803	-1.246204009	normal	0.395123098	-0.986723829	normal	0.163510698	-0.940813772	normal	0.010924909	-1.086829898	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	--	Protein dispatched homolog 2 GN=DISP2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein dispatched homolog 2 [Canis lupus familiaris]
ENSG00000140326(CDAN1)	--	5.239052555	332	3.491850594	329	3.915839178	371	4.730470085	351	3.308873433	307	3.684269672	344	0.967463369	0.049233928	normal	0.960301553	-0.120700982	normal	0.96242803	-0.116807462	normal	0.867888667	-0.063656883	normal	--	--	--	--	--	--	--	Codanin-1 C-terminus	Codanin-1 GN=CDAN1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: codanin-1 [Ceratotherium simum simum]
ENSG00000140332(TLE3)	--	7.496746843	717	6.071023222	562	6.34129	600	6.364160535	624	7.440935998	717	4.863254374	435	0.93991477	-0.230728817	normal	0.862049458	0.3291905	normal	0.50253623	-0.470838599	normal	0.824780737	-0.103397071	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[B]	Chromatin structure and dynamics	"Groucho/TLE N-terminal Q-rich domain;; WD domain, G-beta repeat"	Transducin-like enhancer protein 3 GN=TLE3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: transducin-like enhancer protein 3-like isoform 1 [Tursiops truncatus]
ENSG00000140350(ANP32A)	--	122.4054532	3979	119.8689792	3742	134.9376365	4047	141.4354125	4675	125.0752648	4025	89.7206676	2996	0.983004295	0.201656309	normal	0.990485775	0.08372004	normal	0.675370846	-0.44191399	normal	0.946746066	-0.031233015	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K18646|7.67048e-97|ggo:101145293|ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A; K18646 acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D (A)	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat	Acidic leucine-rich nuclear phosphoprotein 32 family member A GN=ANP32A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	acidic leucine-rich nuclear phosphoprotein 32 family member A [Canis lupus familiaris] 
ENSG00000140365(COMMD4)	--	91.259867	1300	99.61400411	1439	106.3801356	1535	96.280934	1450	91.9777415	1322	93.68336379	1375	0.977180589	0.126567334	normal	0.97490612	-0.143613447	normal	0.972538768	-0.166924623	normal	0.79658904	-0.064714379	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 4 GN=COMMD4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COMM domain-containing protein 4 [Felis catus]
ENSG00000140367(UBE2Q2)	--	28.06735637	1320	30.97493743	1466	29.15252466	1374	33.53671539	1574	31.31601007	1473	33.6889058	1590	0.958545178	0.222827602	normal	0.98337617	-0.014539269	normal	0.965345891	0.202146323	normal	0.516550292	0.135373542	normal	--	--	--	K10582|0|ptr:453772|UBE2Q2; ubiquitin-conjugating enzyme E2Q family member 2; K10582 ubiquitin-conjugating enzyme E2 Q [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; RWD domain	Ubiquitin-conjugating enzyme E2 Q2 GN=UBE2Q2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 Q2 isoform 1 [Ovis aries] 
ENSG00000140374(ETFA)	--	207.6651939	3888	198.507498	3877	189.115797	3820	236.2827061	4488	234.7414478	4389	225.4756813	4381	0.985698743	0.176147366	normal	0.987072708	0.157467221	normal	0.98394199	0.189326096	normal	0.372496881	0.173313073	normal	[C]	Energy production and conversion	--	"K03522|0|hsa:2108|ETFA, EMA, GA2, MADD; electron-transfer-flavoprotein, alpha polypeptide; K03522 electron transfer flavoprotein alpha subunit (A)"	--	[C]	Energy production and conversion	Electron transfer flavoprotein FAD-binding domain;; Electron transfer flavoprotein domain	"Electron transfer flavoprotein subunit alpha, mitochondrial (Precursor) GN=ETFA OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: electron transfer flavoprotein subunit alpha, mitochondrial isoform X1 [Panthera tigris altaica]"
ENSG00000140379(BCL2A1)	--	3.002821	43	0.906302	12	1.694124	21	7.431684	116	6.920271681	106	7.99994	117	0.000369377	1.369950323	up	5.06E-13	2.9720811	up	9.99E-11	2.388292005	up	1.88E-08	2.135807847	up	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K02162|3.55458e-124|ggo:101151416|BCL2A1; bcl-2-related protein A1 isoform 1; K02162 hematopoietic BCL2-related protein A1 (A)	NF-kappa B signaling pathway (ko04064);; Transcriptional misregulation in cancer (ko05202)	[T]	Signal transduction mechanisms	"Apoptosis regulator proteins, Bcl-2 family"	Bcl-2-related protein A1 GN=BCL2A1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bcl-2-related protein A1 [Galeopterus variegatus]
ENSG00000140382(HMG20A)	--	17.278401	1115	16.01532973	1120	14.90481682	1009	16.66555625	1133	18.44451701	1271	18.0318607	1174	0.980869708	-0.007717563	normal	0.970080382	0.16083478	normal	0.957083204	0.20992285	normal	0.586559751	0.120168535	normal	--	--	--	--	--	[R]	General function prediction only	HMG (high mobility group) box;; HMG-box domain	High mobility group protein 20A GN=HMG20A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: high mobility group protein 20A [Sus scrofa] 
ENSG00000140386(SCAPER)	--	3.58633274	359	4.295247125	359	3.39480743	328	4.3030685	423	3.421596855	303	3.2854572	293	0.944518116	0.205032511	normal	0.918862575	-0.264876401	normal	0.953154479	-0.170255565	normal	0.881309871	-0.060323042	normal	--	--	--	--	--	[R]	General function prediction only	Zinc-finger of C2H2 type	S phase cyclin A-associated protein in the endoplasmic reticulum GN=SCAPER OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: S phase cyclin A-associated protein in the endoplasmic reticulum [Ceratotherium simum simum]
ENSG00000140391(TSPAN3)	--	212.1261031	5892	208.22418	5794	206.6485676	5624	296.3727691	7959	259.4089685	6989	321.45341	8592	0.865998779	0.402906793	normal	0.980446129	0.249040548	normal	0.089401654	0.602973822	normal	0.008466431	0.422424552	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17293|6.06258e-170|ptr:467832|TSPAN3; tetraspanin 3; K17293 tetraspanin-3 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-3 GN=TSPAN3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: tetraspanin-3 [Ailuropoda melanoleuca] 
ENSG00000140395(WDR61)	--	41.38843711	894	43.23886839	964	40.12128462	888	37.59201275	833	37.42894105	803	33.05704209	697	0.969878527	-0.13255452	normal	0.913722081	-0.284569803	normal	0.817807542	-0.357004458	normal	0.174410704	-0.256936223	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K12602|0|cjc:100415315|WDR61; WD repeat domain 61; K12602 WD repeat-containing protein 61 (A)	RNA degradation (ko03018)	[R]	General function prediction only	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A;; Cytochrome D1 heme domain;; Nucleoporin Nup120/160"	"WD repeat-containing protein 61, N-terminally processed GN=WDR61 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	PREDICTED: WD repeat-containing protein 61 [Loxodonta africana] 
ENSG00000140396(NCOA2)	--	5.843863964	951	6.331726529	1062	6.174145943	970	6.652146467	1097	6.276182858	1054	7.8207638	1186	0.96503879	0.174950692	normal	0.979374217	-0.032289303	normal	0.920493584	0.281358584	normal	0.514305344	0.140719333	normal	--	--	"Molecular Function: transcription coactivator activity (GO:0003713);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: nuclear hormone receptor binding (GO:0035257);; "	K11255|0|ptr:464226|NCOA2; nuclear receptor coactivator 2; K11255 nuclear receptor coactivator 2 (A)	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	PAS domain;; Domain of unknown function (DUF1518);; Steroid receptor coactivator;; Nuclear receptor coactivator;; PAS fold;; PAS domain	Nuclear receptor coactivator 2 GN=NCOA2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor coactivator 2 [Ceratotherium simum simum]
ENSG00000140398(NEIL1)	--	2.034488592	69	2.195368	92	2.888128	67	3.60150321	81	3.941109126	72	4.085160052	93	0.967093588	0.196452842	normal	0.931590486	-0.368203444	normal	0.899693209	0.456005548	normal	0.902819663	0.088414627	normal	--	--	"Molecular Function: damaged DNA binding (GO:0003684);; Molecular Function: DNA-(apurinic or apyrimidinic site) lyase activity (GO:0003906);; Biological Process: base-excision repair (GO:0006284);; Biological Process: nucleotide-excision repair (GO:0006289);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799);; "	"K10567|0|hsa:79661|NEIL1, FPG1, NEI1, hFPG1; nei endonuclease VIII-like 1 (E. coli) (EC:4.2.99.18); K10567 endonuclease VIII-like 1 [EC:3.2.2.- 4.2.99.18] (A)"	Base excision repair (ko03410)	--	--	"Endonuclease VIII-like 1, DNA bind;; Formamidopyrimidine-DNA glycosylase N-terminal domain;; Formamidopyrimidine-DNA glycosylase H2TH domain"	Endonuclease 8-like 1 GN=NEIL1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: endonuclease 8-like 1 [Bos mutus] 
ENSG00000140400(MAN2C1)	--	17.286465	920	14.32265643	886	12.86904922	880	11.408312	760	13.26098498	792	12.1562833	843	0.891283569	-0.305903588	normal	0.959614048	-0.182902416	normal	0.975903409	-0.070139171	normal	0.368489771	-0.186344503	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: alpha-mannosidase activity (GO:0004559);; Biological Process: mannose metabolic process (GO:0006013);; 	"K01191|0|hsa:4123|MAN2C1, MAN6A8, MANA, MANA1; mannosidase, alpha, class 2C, member 1 (EC:3.2.1.24); K01191 alpha-mannosidase [EC:3.2.1.24] (A)"	Other glycan degradation (ko00511)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolases family 38 N-terminal domain;; Glycosyl hydrolases family 38 C-terminal domain;; Alpha mannosidase, middle domain"	Alpha-mannosidase 2C1 GN=MAN2C1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: alpha-mannosidase 2C1 isoform X2 [Equus caballus]
ENSG00000140403(DNAJA4)	--	0.0195121	1	0.019195798	1	0.019169851	0	0.109357756	4	0.0371333	0	0.019383402	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: heat shock protein binding (GO:0031072);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K09505|0|pps:100989002|DNAJA4; DnaJ (Hsp40) homolog, subfamily A, member 4; K09505 DnaJ homolog subfamily A member 4 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain;; DnaJ central domain	DnaJ homolog subfamily A member 4 (Precursor) GN=DNAJA4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily A member 4 isoform X1 [Loxodonta africana]
ENSG00000140406(MESDC1)	--	10.3096	747	9.26012	686	9.34133	694	12.9346	945	12.6272	915	14.5027	1059	0.889473729	0.307809884	normal	0.744414172	0.393383408	normal	0.068260478	0.600336912	normal	0.008330627	0.435744335	normal	--	--	--	--	--	[Z]	Cytoskeleton	--	Mesoderm development candidate 1 GN=MESDC1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	mesoderm development candidate 1 [Equus caballus]
ENSG00000140416(TPM1)	--	129.063655	4693	140.7941616	5178	152.4053359	5558	506.1876947	19296	490.4749837	18245	322.143403	11839	0	2.00853607	up	0	1.795310023	up	6.92E-09	1.082411484	up	3.19E-06	1.655990642	up	--	--	--	K10373|4.3133e-158|phd:102334133|TPM1; tropomyosin 1 (alpha); K10373 tropomyosin 1 (A)	Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; MicroRNAs in cancer (ko05206);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Tropomyosin;; Tropomyosin like	Tropomyosin alpha-1 chain GN=TPM1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tropomyosin alpha-1 chain isoform X1 [Orycteropus afer afer]
ENSG00000140443(IGF1R)	--	49.4090411	9034	70.32363797	9482	55.14612365	9007	42.36600477	9061	47.260454	9436	52.56015839	10779	0.995892008	-0.026522394	normal	0.995856592	-0.028437986	normal	0.985726021	0.250774795	normal	0.800873711	0.068350086	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);; Cellular Component: membrane (GO:0016020);; 	"K05087|0|hsa:3480|IGF1R, CD221, IGFIR, IGFR, JTK13; insulin-like growth factor 1 receptor (EC:2.7.10.1); K05087 insulin-like growth factor 1 receptor [EC:2.7.10.1] (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Oocyte meiosis (ko04114);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Long-term depression (ko04730);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Receptor L domain;; Protein kinase domain;; Furin-like cysteine rich region;; Fibronectin type III domain	Insulin-like growth factor 1 receptor beta chain (Precursor) GN=IGF1R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: insulin-like growth factor 1 receptor isoform X1 [Bos taurus]
ENSG00000140450(ARRDC4)	--	0.504738	35	0.643618	45	0.329487	22	0.372569	26	0.363311	25	0.387389	27	0.972115793	-0.437317442	normal	0.824143041	-0.831417916	normal	0.983995618	0.270363974	normal	0.590374322	-0.409127707	normal	--	--	--	--	--	[R]	General function prediction only	"Arrestin (or S-antigen), N-terminal domain;; Arrestin (or S-antigen), C-terminal domain"	Arrestin domain-containing protein 4 GN=ARRDC4 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: arrestin domain-containing protein 4 [Trichechus manatus latirostris]
ENSG00000140451(PIF1)	--	5.614390305	319	5.821580377	343	5.407753579	292	4.39182986	249	4.03706925	235	4.3853364	254	0.805119051	-0.386131703	normal	0.317875202	-0.563951328	normal	0.944002105	-0.208273774	normal	0.121743891	-0.391759599	normal	[L]	"Replication, recombination and repair"	Biological Process: telomere maintenance (GO:0000723);; Molecular Function: DNA helicase activity (GO:0003678);; Biological Process: DNA repair (GO:0006281);; 	"K15255|0|hsa:80119|PIF1, C15orf20, PIF; PIF1 5'-to-3' DNA helicase (EC:3.6.4.12); K15255 ATP-dependent DNA helicase PIF1 [EC:3.6.4.12] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	PIF1-like helicase;; AAA domain;; Helicase	ATP-dependent DNA helicase PIF1 {ECO:0000255|HAMAP-Rule:MF_03176} OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: ATP-dependent DNA helicase PIF1 isoform X2 [Mustela putorius furo] 
ENSG00000140455(USP3)	--	24.905025	1243	26.79659712	1280	27.42512387	1177	23.95724588	1144	27.75997063	1359	23.36436155	1187	0.972061604	-0.150377672	normal	0.980852495	0.064900667	normal	0.981507456	0.003909171	normal	0.93492335	-0.025032823	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11986|0|pon:100454247|USP3; ubiquitin specific peptidase 3; K11986 ubiquitin carboxyl-terminal hydrolase 3 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein	Ubiquitin carboxyl-terminal hydrolase 3 GN=USP3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 3 isoform X1 [Orycteropus afer afer]
ENSG00000140459(CYP11A1)	--	0.031719971	1	0	0	0	0	0.031536847	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00498|0|hsa:1583|CYP11A1, CYP11A, CYPXIA1, P450SCC; cytochrome P450, family 11, subfamily A, polypeptide 1 (EC:1.14.15.6); K00498 cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6] (A)"	Steroid hormone biosynthesis (ko00140);; Ovarian steroidogenesis (ko04913)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	"Cholesterol side-chain cleavage enzyme, mitochondrial (Precursor) GN=CYP11A1 OS=Homo sapiens (Human) PE=1 SV=2"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: cholesterol side-chain cleavage enzyme, mitochondrial-like [Leptonychotes weddellii]"
ENSG00000140463(BBS4)	--	12.41172374	625	10.40138003	491	10.38578695	502	12.477796	637	14.69412937	716	15.20405858	701	0.974210187	-0.003386834	normal	0.30972799	0.521472735	normal	0.479788102	0.472226407	normal	0.099367069	0.323226089	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K16531|0|ggo:101139659|BBS4; Bardet-Biedl syndrome 4 protein isoform 1; K16531 Bardet-Biedl syndrome 4 protein (A)	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Bardet-Biedl syndrome 4 protein GN=BBS4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: Bardet-Biedl syndrome 4 protein isoform X1 [Panthera tigris altaica]
ENSG00000140464(PML)	--	8.387062568	441	9.102634853	428	11.13792914	502	11.63838152	608	11.9119227	713	12.83416362	669	0.638874029	0.431176298	normal	0.011330933	0.712893251	normal	0.710340917	0.404967144	normal	0.004118109	0.51696246	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	K10054|0|ptr:453736|PML; promyelocytic leukemia; K10054 probable transcription factor PML (A)	Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Acute myeloid leukemia (ko05221)	[O]	"Posttranslational modification, protein turnover, chaperones"	Protein of unknown function (DUF3583);; B-box zinc finger	Protein PML GN=PML OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: protein PML isoform X1 [Galeopterus variegatus]
ENSG00000140465(CYP1A1)	--	1.042440777	55	0.48586159	28	0.38312305	20	0.138512136	7	0.417330329	14	0.195181508	9	1.05E-06	-2.755110156	down	0.906712055	-0.947737632	normal	0.946489425	-1.040487926	normal	0.073763899	-1.800840368	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07408|0|hsa:1543|CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX; cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1); K07408 cytochrome P450, family 1, subfamily A, polypeptide 1 [EC:1.14.14.1] (A)"	Steroid hormone biosynthesis (ko00140);; Tryptophan metabolism (ko00380);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Ovarian steroidogenesis (ko04913);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 1A1 GN=CYP1A1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 1A1 [Galeopterus variegatus]
ENSG00000140470(ADAMTS17)	--	0	0	0	0	0.007798781	0	0	0	0	0	0.023880835	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08631|0|hsa:170691|ADAMTS17; ADAM metallopeptidase with thrombospondin type 1 motif, 17; K08631 a disintegrin and metalloproteinase with thrombospondin motifs 17 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thrombospondin type 1 domain;; Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; ADAM-TS Spacer 1;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; PLAC (protease and lacunin) domain	A disintegrin and metalloproteinase with thrombospondin motifs 17 (Precursor) GN=ADAMTS17 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 17 [Odobenus rosmarus divergens]
ENSG00000140471(LINS1)	--	5.807808406	267	5.793638086	282	5.569904777	263	5.5060785	276	5.435773666	299	7.587545684	337	0.967270297	0.016900609	normal	0.96498482	0.062697217	normal	0.854651723	0.34762424	normal	0.659705643	0.146882574	normal	--	--	--	--	--	--	--	Lines N-terminus;; Lines C-terminus	Protein Lines homolog GN=LINS OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: protein Lines homolog isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000140474(ULK3)	--	12.4631925	640	14.74381638	774	12.33686831	649	11.95055728	616	11.58557666	591	18.13103372	943	0.970853999	-0.085763928	normal	0.700579384	-0.409682889	normal	0.236555332	0.52971809	normal	0.954699822	0.039479156	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08269|0|ptr:453747|ULK3; unc-51 like kinase 3; K08269 serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1] (A)	Regulation of autophagy (ko04140);; mTOR signaling pathway (ko04150)	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Protein kinase domain;; Protein tyrosine kinase;; MIT (microtubule interacting and transport) domain;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase ULK3 GN=ULK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	serine/threonine-protein kinase ULK3 [Bos taurus] 
ENSG00000140478(GOLGA6D)	--	0.027100767	2	0.039409629	3	0	0	0.013391089	1	0.013182604	0	0.053745375	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Putative golgin subfamily A member 6D GN=GOLGA6D OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X2 [Felis catus]
ENSG00000140479(PCSK6)	--	3.746667235	274	5.3338819	356	4.308318367	269	8.76775736	694	10.57210739	742	7.723673896	658	3.30E-10	1.3051706	up	2.47E-06	1.035004302	up	1.15E-09	1.277446649	up	9.58E-13	1.19824121	up	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	K08672|0|ptr:743234|PCSK6; proprotein convertase subtilisin/kexin type 6; K08672 proprotein convertase subtilisin/kexin type 6 [EC:3.4.21.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family;; Proprotein convertase P-domain;; Growth factor receptor domain IV	Proprotein convertase subtilisin/kexin type 6 (Precursor) GN=PCSK6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: proprotein convertase subtilisin/kexin type 6, partial [Oryctolagus cuniculus]"
ENSG00000140481(CCDC33)	--	1.743219922	52	0.765569775	16	0.859200163	22	0.579393776	14	0.759835029	15	0.55965216	8	0.003105554	-1.813728674	down	--	--	--	0.853195633	-1.312916405	normal	--	--	--	--	--	--	--	--	--	--	C2 domain	Coiled-coil domain-containing protein 33 GN=CCDC33 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 33 isoform X2 [Galeopterus variegatus]
ENSG00000140488(CELF6)	--	0.138410658	10	0.246530066	20	0.132444641	8	0.099479875	8	0.219365924	16	0.347526008	24	--	--	--	0.986437258	-0.316541758	normal	0.752469114	1.415941459	normal	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13207|0|pps:100985107|CELF6; CUGBP, Elav-like family member 6; K13207 CUG-BP- and ETR3-like factor (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	CUGBP Elav-like family member 6 GN=CELF6 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: CUGBP Elav-like family member 6 isoform X1 [Equus przewalskii] 
ENSG00000140497(SCAMP2)	--	40.52330536	1558	39.4386914	1521	39.19126103	1534	46.23911316	1823	48.86284229	1909	53.25675203	2038	0.969308475	0.195608603	normal	0.917348554	0.306098228	normal	0.747645925	0.401219857	normal	0.064556011	0.302016066	normal	--	--	Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SCAMP family	Secretory carrier-associated membrane protein 2 GN=SCAMP2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: secretory carrier-associated membrane protein 2 [Oryctolagus cuniculus]
ENSG00000140511(HAPLN3)	--	7.62451167	219	5.006433535	147	7.3167564	220	10.58610443	312	12.95366544	373	8.038609829	235	0.614723736	0.476966674	normal	4.60E-08	1.313156533	up	0.964020457	0.086291778	normal	0.07819642	0.629359191	normal	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	"K06852|0|hsa:145864|HAPLN3, EXLD1, HsT19883; hyaluronan and proteoglycan link protein 3; K06852 hyaluronan and proteoglycan link protein 3 (A)"	--	--	--	Extracellular link domain;; Immunoglobulin V-set domain	Hyaluronan and proteoglycan link protein 3 (Precursor) GN=HAPLN3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: hyaluronan and proteoglycan link protein 3 isoform X2 [Sus scrofa]
ENSG00000140519(RHCG)	--	1.454511006	48	1.340266223	46	0.908861931	31	4.380197342	150	3.905787059	131	8.770790189	302	1.09E-06	1.582904139	up	3.62E-05	1.45879025	up	0	3.214619973	up	0.013524886	2.201851261	normal	--	--	Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; 	"K06580|0|hsa:51458|RHCG, C15orf6, PDRC2, RHGK, SLC42A3; Rh family, C glycoprotein; K06580 ammonium transporter Rh (A)"	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Ammonium Transporter Family	Ammonium transporter Rh type C GN=RHCG OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: ammonium transporter Rh type C isoform X3 [Tupaia chinensis]
ENSG00000140521(POLG)	--	16.83001433	1607	15.77058163	1569	16.0678446	1589	18.64792432	1781	19.02741138	1809	18.625885	1766	0.980799954	0.117378696	normal	0.971663789	0.183755444	normal	0.977981332	0.143944774	normal	0.46569539	0.14748555	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Biological Process: DNA replication (GO:0006260);; 	"K02332|0|hsa:5428|POLG, MDP1, MIRAS, MTDPS4A, MTDPS4B, PEO, POLG1, POLGA, SANDO, SCAE; polymerase (DNA directed), gamma (EC:2.7.7.7); K02332 DNA polymerase gamma 1 [EC:2.7.7.7] (A)"	--	[L]	"Replication, recombination and repair"	DNA polymerase family A	DNA polymerase subunit gamma-1 GN=POLG OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase subunit gamma-1 [Ceratotherium simum simum]
ENSG00000140522(RLBP1)	--	0	0	0	0	0.085592138	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	"CRAL/TRIO domain;; Divergent CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain"	Retinaldehyde-binding protein 1 GN=RLBP1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: retinaldehyde-binding protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000140525(FANCI)	--	54.563688	3362	49.944128	3145	60.09682359	3714	52.579653	3313	47.0861569	2931	50.941939	3029	0.990489102	-0.05198985	normal	0.986601996	-0.123032308	normal	0.94436326	-0.302287134	normal	0.408150727	-0.161677002	normal	--	--	--	"K10895|0|hsa:55215|FANCI, KIAA1794; Fanconi anemia, complementation group I; K10895 fanconi anemia group I protein (A)"	Fanconi anemia pathway (ko03460)	[S]	Function unknown	FANCI solenoid 4;; FANCI helical domain 2;; FANCI solenoid 3;; FANCI solenoid 1;; FANCI solenoid 2;; FANCI helical domain 1;; FANCI solenoid 1 cap	Fanconi anemia group I protein GN=FANCI OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: Fanconi anemia group I protein isoform X1 [Equus caballus] 
ENSG00000140526(ABHD2)	--	34.31848133	4991	40.1220946	5836	38.28238587	5463	35.71966057	5227	35.714092	5241	35.79427124	5185	0.993373464	0.03581122	normal	0.988256993	-0.176516036	normal	0.992749332	-0.083617113	normal	0.748052226	-0.078769592	normal	[R]	General function prediction only	--	"K13697|0|hsa:11057|ABHD2, HS1-2, LABH2, PHPS1-2; abhydrolase domain containing 2; K13697 abhydrolase domain-containing protein 2 (A)"	--	[R]	General function prediction only	alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Abhydrolase domain-containing protein 2 GN=ABHD2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: abhydrolase domain-containing protein 2 [Vicugna pacos]
ENSG00000140527(WDR93)	--	0.081468286	3	0.028818	1	0.0287582	0	0.0868303	3	0.140700844	5	0.051658178	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	WD repeat-containing protein 93 GN=WDR93 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: WD repeat-containing protein 93 [Galeopterus variegatus]
ENSG00000140534(TICRR)	--	7.6622	1132	8.1436	1193	8.98528	1316	6.959089	1022	7.553589	1112	8.7931	1300	0.965248236	-0.178056526	normal	0.974821088	-0.122702661	normal	0.982407313	-0.025909351	normal	0.642073578	-0.104692863	normal	--	--	--	--	--	--	--	Treslin N-terminus	Treslin GN=TICRR OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: treslin [Galeopterus variegatus]
ENSG00000140538(NTRK3)	--	2.703229926	195	2.467286958	175	2.933263948	203	11.35308884	601	15.41920176	1193	10.91948662	796	4.29E-14	1.585579035	up	0	2.737259948	up	0	1.955066291	up	0.000238406	2.15632602	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05101|0|cjc:100413191|NTRK3; neurotrophic tyrosine kinase, receptor, type 3; K05101 neurotrophic tyrosine kinase, receptor type 3 [EC:2.7.10.1] (A)"	Neurotrophin signaling pathway (ko04722);; Central carbon metabolism in cancer (ko05230)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Leucine rich repeat;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Leucine rich repeat N-terminal domain	NT-3 growth factor receptor (Precursor) GN=NTRK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: NT-3 growth factor receptor isoform X1 [Galeopterus variegatus]
ENSG00000140543(DET1)	--	4.467124	271	3.755837	257	3.27670894	193	3.571767829	201	3.392025	195	4.86454686	274	0.688872738	-0.458895982	normal	0.783616839	-0.41689477	normal	0.601218707	0.494018912	normal	0.775772614	-0.126635354	normal	--	--	--	K10571|0|mcf:102125653|DET1; de-etiolated homolog 1 (Arabidopsis); K10571 de-etiolated-1 (A)	Ubiquitin mediated proteolysis (ko04120)	[K]	Transcription	De-etiolated protein 1 Det1	DET1 homolog GN=DET1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DET1 homolog isoform X1 [Vicugna pacos]
ENSG00000140545(MFGE8)	--	117.9628762	3784	118.8479896	3894	120.9793972	3958	99.65492216	3205	123.149079	3936	102.8138062	3367	0.962044896	-0.270300571	normal	0.991772269	-0.005946924	normal	0.972569509	-0.241499173	normal	0.387606733	-0.16800905	normal	--	--	--	K17253|0|ptr:453631|MFGE8; milk fat globule-EGF factor 8 protein; K17253 lactadherin (A)	--	--	--	F5/8 type C domain;; EGF-like domain	Medin (Precursor) GN=MFGE8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"milk fat globule-EGF factor 8 splice variant, partial [Equus caballus]"
ENSG00000140548(ZNF710)	--	12.99933032	481	14.29649365	433	9.535077	388	10.32605109	535	8.21317679	549	7.229198	432	0.964538067	0.122299219	normal	0.872543769	0.320017946	normal	0.959068827	0.146143161	normal	0.425569631	0.197536057	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; CHY zinc finger"	Zinc finger protein 710 GN=ZNF710 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 710 [Balaenoptera acutorostrata scammoni]
ENSG00000140553(UNC45A)	--	33.82333232	2379	33.42120246	2415	36.09223036	2615	31.48301243	2216	32.89799916	2285	35.07372871	2463	0.983116	-0.133140532	normal	0.985364611	-0.101190426	normal	0.986778088	-0.094629362	normal	0.60808479	-0.110078878	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[ODR]	"Posttranslational modification, protein turnover, chaperones;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Myosin-binding striated muscle assembly central;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Protein unc-45 homolog A GN=UNC45A OS=Homo sapiens (Human) PE=1 SV=1	DO	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein unc-45 homolog A isoform X4 [Canis lupus familiaris]
ENSG00000140557(ST8SIA2)	--	0.037656213	3	0	0	0.00896973	0	0	0	0.05408822	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K06612|0|hsa:8128|ST8SIA2, HsT19690, SIAT8B, ST8SIA-II, STX; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2; K06612 alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8B) [EC:2.4.99.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-2,8-sialyltransferase 8B GN=ST8SIA2 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-2,8-sialyltransferase 8B isoform X1 [Bos taurus] "
ENSG00000140564(FURIN)	--	26.87947921	2264	25.10441701	1622	21.79642147	1882	42.15441169	3542	52.39951689	4396	31.49900114	2670	0.045565461	0.614522055	normal	3.44E-15	1.416156409	up	0.378690751	0.495945441	normal	0.014786019	0.857266291	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01349|0|hsa:5045|FURIN, FUR, PACE, PCSK3, SPC1; furin (paired basic amino acid cleaving enzyme) (EC:3.4.21.75); K01349 furin [EC:3.4.21.75] (A)"	Influenza A (ko05164)	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family;; Proprotein convertase P-domain	Furin (Precursor) GN=FURIN OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: furin isoform X2 [Vicugna pacos]
ENSG00000140575(IQGAP1)	--	60.0878728	9163	62.39974916	9327	60.31289764	9085	80.16743852	12077	65.51549183	9946	75.91112243	11450	0.940918846	0.36748412	normal	0.995543647	0.071265565	normal	0.966176194	0.325449378	normal	0.17439731	0.258164709	normal	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of GTPase activity (GO:0043087);; 	"K16848|0|hsa:8826|IQGAP1, HUMORFA01, SAR1, p195; IQ motif containing GTPase activating protein 1; K16848 Ras GTPase-activating-like protein IQGAP1 (A)"	Adherens junction (ko04520);; Regulation of actin cytoskeleton (ko04810);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; RasGAP C-terminus;; IQ calmodulin-binding motif;; Calponin homology (CH) domain	Ras GTPase-activating-like protein IQGAP1 GN=IQGAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating-like protein IQGAP1 [Galeopterus variegatus]
ENSG00000140577(CRTC3)	--	11.49977267	1102	11.192952	1024	10.07730992	920	10.55296685	970	10.46156154	1000	11.24133743	1042	0.954344051	-0.214580669	normal	0.978075228	-0.055559239	normal	0.965295195	0.17109365	normal	0.898038535	-0.037398516	normal	--	--	Molecular Function: cAMP response element binding protein binding (GO:0008140);; Biological Process: protein homotetramerization (GO:0051289);; 	"K16334|0|hsa:64784|CRTC3, TORC-3, TORC3; CREB regulated transcription coactivator 3; K16334 CREB-regulated transcription coactivator 3 (A)"	HTLV-I infection (ko05166)	--	--	"Transducer of regulated CREB activity middle domain;; Transducer of regulated CREB activity, C terminus;; Transducer of regulated CREB activity, N terminus"	CREB-regulated transcription coactivator 3 GN=CRTC3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CREB-regulated transcription coactivator 3 [Camelus dromedarius]
ENSG00000140598(EFL1)	--	13.394237	1084	13.61503251	1104	15.14532466	1133	17.45794429	1418	14.37365968	1144	17.41456418	1410	0.832929208	0.356217957	normal	0.980137019	0.029880114	normal	0.903236766	0.306887979	normal	0.186588154	0.237002627	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K14536|0|ptr:453590|EFTUD1; elongation factor Tu GTP binding domain containing 1; K14536 ribosome assembly protein 1 [EC:3.6.5.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[J]	"Translation, ribosomal structure and biogenesis"	"Elongation factor Tu GTP binding domain;; Elongation factor G C-terminus;; Elongation Factor G, domain II;; Elongation factor Tu domain 2;; Elongation factor G, domain IV"	Elongation factor Tu GTP-binding domain-containing protein 1 GN=EFTUD1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: elongation factor Tu GTP-binding domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000140600(SH3GL3)	--	0.43751309	15	0.115292293	4	0.05727453	1	0.232807523	8	0.140948343	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	K11247|0|nle:100602750|SH3GL3; SH3-domain GRB2-like 3; K11247 endophilin-A (A)	Endocytosis (ko04144)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	BAR domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Bin/amphiphysin/Rvs domain for vesicular trafficking	Endophilin-A3 GN=SH3GL3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endophilin-A3 isoform X1 [Tupaia chinensis]
ENSG00000140612(SEC11A)	--	196.5982314	3932	184.71773	3833	183.41371	3630	199.80491	4195	197.76124	3945	221.78921	4505	0.991616516	0.062551561	normal	0.991668188	0.020116921	normal	0.95025023	0.303152538	normal	0.543283311	0.129044943	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K13280|1.95848e-132|mcf:102139920|SEC11A; SEC11 homolog A (S. cerevisiae); K13280 signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-] (A)"	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Peptidase S24-like	Signal peptidase complex catalytic subunit SEC11A GN=SEC11A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: SEC11 homolog A (S. cerevisiae) [Tupaia chinensis]
ENSG00000140623(SEPT12)	--	0	0	0	0	0	0	0	0	0	0	0.046328318	1	--	--	--	--	--	--	--	--	--	--	--	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K16938|0|ptr:748303|SEPT12; septin 12; K16938 septin 3/9/12 (A)	Bacterial invasion of epithelial cells (ko05100)	[DTZ]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms;; Cytoskeleton"	Septin;; 50S ribosome-binding GTPase;; AIG1 family;; FtsK/SpoIIIE family	Septin-12 GN=SEPT12 OS=Homo sapiens (Human) PE=1 SV=1	DTZ	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms;; Cytoskeleton"	PREDICTED: septin-12 [Tupaia chinensis]
ENSG00000140632(GLYR1)	--	18.4961226	1404	19.05671968	1418	17.19765399	1329	23.01339889	1747	22.63207951	1735	22.59785016	1780	0.929889666	0.284225131	normal	0.940566257	0.269391467	normal	0.701064196	0.412837389	normal	0.046729969	0.32090897	normal	[I]	Lipid transport and metabolism	Molecular Function: DNA binding (GO:0003677);; Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[R]	General function prediction only	NAD binding domain of 6-phosphogluconate dehydrogenase;; NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase;; PWWP domain;; NADP oxidoreductase coenzyme F420-dependent	Putative oxidoreductase GLYR1 GN=GLYR1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: putative oxidoreductase GLYR1 isoform X3 [Loxodonta africana]
ENSG00000140650(PMM2)	--	30.40457542	1363	31.66457515	1436	28.19661906	1279	30.98845782	1412	37.76038176	1696	30.383211	1383	0.983089529	0.020100002	normal	0.961794077	0.218441986	normal	0.978924114	0.104374743	normal	0.584775034	0.117860522	normal	[R]	General function prediction only	Molecular Function: phosphomannomutase activity (GO:0004615);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: GDP-mannose biosynthetic process (GO:0009298);; 	"K17497|0|hsa:5373|PMM2, CDG1, CDG1a, CDGS, PMI, PMI1, PMM_2; phosphomannomutase 2 (EC:5.4.2.8); K17497 phosphomannomutase [EC:5.4.2.8] (A)"	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[I]	Lipid transport and metabolism	Eukaryotic phosphomannomutase;; haloacid dehalogenase-like hydrolase	Phosphomannomutase 2 GN=PMM2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: phosphomannomutase 2 [Oryctolagus cuniculus]
ENSG00000140675(SLC5A2)	--	0	0	0.41072	2	0	0	0	0	0.0608303	1	0.030934814	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14382|0|hsa:6524|SLC5A2, SGLT2; solute carrier family 5 (sodium/glucose cotransporter), member 2; K14382 solute carrier family 5 (sodium/glucose cotransporter), member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium/glucose cotransporter 2 GN=SLC5A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	sodium/glucose cotransporter 2 [Canis lupus familiaris] 
ENSG00000140678(ITGAX)	--	0.777064641	35	0.332806375	17	0.478194655	24	2.014654373	118	2.233134693	142	1.413371717	99	3.82E-06	1.680055704	up	4.44E-16	2.934180764	up	5.60E-07	1.970124365	up	2.60E-09	2.218389943	up	--	--	--	"K06462|0|hsa:3687|ITGAX, CD11C, SLEB6; integrin, alpha X (complement component 3 receptor 4 subunit); K06462 integrin alpha X (A)"	Regulation of actin cytoskeleton (ko04810);; Tuberculosis (ko05152)	[W]	Extracellular structures	Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; von Willebrand factor type A domain;; Integrin alpha cytoplasmic region	Integrin alpha-X (Precursor) GN=ITGAX OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: integrin alpha-X [Galeopterus variegatus]
ENSG00000140682(TGFB1I1)	--	14.13862431	394	21.61938496	590	18.00576631	512	32.64571508	898	30.07910861	833	23.5174964	657	1.53E-08	1.154624982	up	0.471349688	0.475145398	normal	0.82818854	0.350541849	normal	0.008401701	0.652606697	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain;; Paxillin family	Transforming growth factor beta-1-induced transcript 1 protein GN=TGFB1I1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: transforming growth factor beta-1-induced transcript 1 protein isoform X1 [Orycteropus afer afer]
ENSG00000140688(C16orf58)	--	22.9050006	1274	20.4014876	1157	19.708791	1122	20.22084675	1115	24.62424365	1343	22.07133105	1245	0.954377723	-0.222866253	normal	0.964143494	0.19340907	normal	0.973289166	0.141600369	normal	0.89250799	0.038739226	normal	--	--	--	--	--	[S]	Function unknown	Vitamin B6 photo-protection and homoeostasis	RUS1 family protein C16orf58 GN=C16orf58 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: RUS1 family protein C16orf58 homolog isoform X1 [Ailuropoda melanoleuca] 
ENSG00000140691(ARMC5)	--	3.8681901	263	4.52973065	293	4.236082499	293	3.180191163	209	3.980869441	242	4.843748725	306	0.856142104	-0.36002668	normal	0.90424007	-0.295638268	normal	0.966615286	0.054066465	normal	0.5643595	-0.185439658	normal	--	--	--	--	--	--	--	Armadillo/beta-catenin-like repeat	Armadillo repeat-containing protein 5 GN=ARMC5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: armadillo repeat-containing protein 5 [Equus przewalskii]
ENSG00000140694(PARN)	--	30.44134359	1742	28.30658236	1586	27.33800751	1572	26.01407815	1511	27.95276262	1594	24.40725102	1417	0.956555917	-0.235849631	normal	0.984211297	-0.014154237	normal	0.974415806	-0.157892835	normal	0.508496215	-0.137233712	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: poly(A)-specific ribonuclease activity (GO:0004535);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: mRNA catabolic process (GO:0006402);; Molecular Function: metal ion binding (GO:0046872);; 	K01148|0|ptr:453936|PARN; poly(A)-specific ribonuclease; K01148 poly(A)-specific ribonuclease [EC:3.1.13.4] (A)	RNA degradation (ko03018)	[L]	"Replication, recombination and repair"	CAF1 family ribonuclease;; RNA binding domain	Poly(A)-specific ribonuclease PARN GN=PARN OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: poly(A)-specific ribonuclease PARN isoform 1 [Ceratotherium simum simum]
ENSG00000140718(FTO)	--	32.03393309	1016	30.4728637	862	34.65356632	1055	31.0928801	916	41.66200583	1180	28.1699541	830	0.962935678	-0.180026266	normal	0.633447966	0.430951937	normal	0.82755255	-0.353778026	normal	0.958188686	-0.024499219	normal	--	--	--	--	--	--	--	FTO catalytic domain;; FTO C-terminal domain	Alpha-ketoglutarate-dependent dioxygenase FTO GN=FTO OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	alpha-ketoglutarate-dependent dioxygenase FTO [Oryctolagus cuniculus] 
ENSG00000140740(UQCRC2)	--	101.6736069	2735	107.542404	2648	117.871508	2830	128.1334089	3179	113.76138	3124	97.8337236	2491	0.980162617	0.186102884	normal	0.974164273	0.216950597	normal	0.977662236	-0.192258886	normal	0.742874168	0.076854641	normal	[R]	General function prediction only	--	"K00415|0|hsa:7385|UQCRC2, MC3DN5, QCR2, UQCR2; ubiquinol-cytochrome c reductase core protein II (EC:1.10.2.2); K00415 ubiquinol-cytochrome c reductase core subunit 2 (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Insulinase (Peptidase family M16);; Peptidase M16 inactive domain	"Cytochrome b-c1 complex subunit 2, mitochondrial (Precursor) GN=UQCRC2 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: cytochrome b-c1 complex subunit 2, mitochondrial [Oryctolagus cuniculus]"
ENSG00000140743(CDR2)	--	13.93080746	741	11.998205	738	13.87523171	850	21.52611	1179	17.83695104	1020	19.88365933	1135	0.029352636	0.638128511	normal	0.582042895	0.444671743	normal	0.695241835	0.408235465	normal	0.001542553	0.496432115	normal	--	--	--	--	--	--	--	--	Cerebellar degeneration-related protein 2 GN=CDR2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cerebellar degeneration-related protein 2 [Ceratotherium simum simum]
ENSG00000140749(IGSF6)	--	0.13447702	6	0.067507806	3	0.179512002	7	0.044550817	2	0.064822	2	0.177125374	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain	Immunoglobulin superfamily member 6 (Precursor) GN=IGSF6 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 6 [Galeopterus variegatus]
ENSG00000140750(ARHGAP17)	--	9.843025834	767	10.73697666	824	10.4961313	817	13.32400397	975	11.00121943	855	10.5655888	773	0.882356865	0.314783008	normal	0.976601854	0.031796237	normal	0.973669387	-0.087991635	normal	0.721029296	0.090465951	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	BAR domain;; RhoGAP domain	Rho GTPase-activating protein 17 GN=ARHGAP17 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 17 isoform X2 [Oryctolagus cuniculus]
ENSG00000140795(MYLK3)	--	0.0735218	8	0.036609819	5	0.079047976	8	0.026609194	3	0.008624691	0	0.035248172	4	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K00907|0|hsa:91807|MYLK3, MLCK, MLCK2, caMLCK; myosin light chain kinase 3 (EC:2.7.11.18); K00907 myosin-light-chain kinase [EC:2.7.11.18] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Myosin light chain kinase 3 GN=MYLK3 OS=Homo sapiens (Human) PE=2 SV=3	Z	Cytoskeleton	PREDICTED: myosin light chain kinase 3 [Ceratotherium simum simum]
ENSG00000140807(NKD1)	--	0.269023	97	0.125721	46	0.179303	65	0.122344	44	0.465571	167	0.0881825	32	0.017736126	-1.143706978	normal	5.37E-09	1.805491776	up	0.344575781	-0.996940809	normal	0.923805752	0.20351475	normal	--	--	--	"K03213|0|hsa:85407|NKD1, Naked1; naked cuticle homolog 1 (Drosophila); K03213 naked cuticle (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390)	--	--	--	Protein naked cuticle homolog 1 GN=NKD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	protein naked cuticle homolog 1 [Bos taurus] 
ENSG00000140829(DHX38)	--	14.40920402	1415	19.32886	1691	15.045346	1561	16.039731	1576	17.679004	1591	15.77407846	1633	0.978528592	0.124505083	normal	0.980761388	-0.109268616	normal	0.983747334	0.056709094	normal	0.95263579	0.019430986	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	"K12815|0|hsa:9785|DHX38, DDX38, PRP16, PRPF16; DEAH (Asp-Glu-Ala-His) box polypeptide 38 (EC:3.6.4.13); K12815 pre-mRNA-splicing factor ATP-dependent RNA helicase DHX38/PRP16 [EC:3.6.4.13] (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; AAA domain	Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 GN=DHX38 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 isoform X1 [Galeopterus variegatus]
ENSG00000140830(TXNL4B)	--	11.36604	404	10.94599	395	11.072	449	11.50110359	466	12.38775	462	13.80515	524	0.95358052	0.174524043	normal	0.944768007	0.203891264	normal	0.943091635	0.213892446	normal	0.436464399	0.19778864	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Cellular Component: spliceosomal complex (GO:0005681);; Biological Process: cell redox homeostasis (GO:0045454);; "	--	--	[AD]	"RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	Mitosis protein DIM1;; Thioredoxin	Thioredoxin-like protein 4B GN=TXNL4B OS=Homo sapiens (Human) PE=1 SV=1	AD	"RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: thioredoxin-like protein 4B [Eptesicus fuscus]
ENSG00000140832(MARVELD3)	--	0.166390554	7	0.203937407	10	0	0	0.297374549	16	0.114352446	5	0.313262487	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MARVEL domain-containing protein 3 GN=MARVELD3 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: MARVEL domain-containing protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000140835(CHST4)	--	0.335826523	14	0.284198	14	0.237622	9	0.203026771	8	0.336119014	13	0.202027331	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K04746|0|hsa:10164|CHST4, GST3, GlcNAc6ST2, HECGLCNAC6ST, LSST; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4; K04746 carbohydrate 6-sulfotransferase 4 [EC:2.8.2.-] (A)"	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533)	--	--	Sulfotransferase domain;; Sulfotransferase family	Carbohydrate sulfotransferase 4 GN=CHST4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	hypothetical protein PANDA_009823 [Ailuropoda melanoleuca]
ENSG00000140836(ZFHX3)	--	7.484661599	2269	10.25804286	3127	8.196103542	2482	8.77897	2640	8.307024031	2614	8.818751178	2807	0.977201146	0.187531252	normal	0.953076155	-0.279798407	normal	0.980989675	0.169137545	normal	0.977448148	0.011898685	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K09378|0|mcf:102126116|ZFHX3; zinc finger homeobox 3; K09378 AT-binding transcription factor 1 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[R]	General function prediction only	"Homeobox domain;; Homeobox KN domain;; Zinc finger, C2H2 type;; Zinc-finger of C2H2 type"	Zinc finger homeobox protein 3 GN=ZFHX3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger homeobox protein 3 [Equus caballus]
ENSG00000140839(CLEC18B)	--	0	0	0.022116819	1	0.054034055	1	0.141056844	5	0.245696369	8	0.13358224	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family;; Lectin C-type domain;; Human growth factor-like EGF	C-type lectin domain family 18 member B (Precursor) GN=CLEC18B OS=Homo sapiens (Human) PE=2 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 18 member A-like [Pteropus alecto]
ENSG00000140848(CPNE2)	--	22.89412876	1048	18.98741944	903	20.45938146	992	22.17276171	1038	19.79109007	965	19.32722651	925	0.97930528	-0.044598837	normal	0.976099014	0.074256089	normal	0.97420883	-0.109006066	normal	0.925960777	-0.028857657	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-2 GN=CPNE2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: copine-2 isoform X1 [Felis catus]
ENSG00000140853(NLRC5)	--	0.907864214	85	1.2089859	140	0.982133238	105	2.716512976	317	2.347675471	289	2.865941667	285	5.38E-14	1.849594089	up	0.000290572	1.016415544	up	2.38E-08	1.419366433	up	2.51E-09	1.411198528	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	NACHT domain;; Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat	Protein NLRC5 GN=NLRC5 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein NLRC5 [Balaenoptera acutorostrata scammoni]
ENSG00000140854(KATNB1)	--	11.99107772	696	11.48683092	621	15.5056683	863	11.31214933	647	9.421673156	545	9.086674188	507	0.965933317	-0.135842727	normal	0.946197207	-0.209219268	normal	0.00161351	-0.773875694	normal	0.126497932	-0.381085131	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K18643|0|hsa:10300|KATNB1, KAT; katanin p80 (WD repeat containing) subunit B 1; K18643 katanin p80 WD40 repeat-containing subunit B1 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"WD domain, G-beta repeat;; con80 domain of Katanin"	Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022} OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: katanin p80 WD40 repeat-containing subunit B1 [Tupaia chinensis]
ENSG00000140859(KIFC3)	--	94.427723	4982	87.12925699	4850	85.01954809	4913	99.33338988	5037	127.465021	6344	129.987032	6032	0.993417116	-0.014987957	normal	0.913614112	0.365881449	normal	0.966275443	0.287660703	normal	0.238320253	0.219352012	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10406|0|ggo:101142982|KIFC3; kinesin-like protein KIFC3 isoform 1; K10406 kinesin family member C2/C3 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIFC3 GN=KIFC3 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIFC3 [Vicugna pacos]
ENSG00000140873(ADAMTS18)	--	0.12482071	14	0.035255258	4	0.05251028	5	0.02671796	3	0.05186201	5	0.026586833	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; 	"K08632|0|hsa:170692|ADAMTS18, ADAMTS21, KNO2, MMCAT; ADAM metallopeptidase with thrombospondin type 1 motif, 18; K08632 a disintegrin and metalloproteinase with thrombospondin motifs 18 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin family propeptide;; Thrombospondin type 1 domain;; Reprolysin (M12B) family zinc metalloprotease;; PLAC (protease and lacunin) domain;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 18 (Precursor) GN=ADAMTS18 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 18 [Ceratotherium simum simum]
ENSG00000140876(NUDT7)	--	8.076876033	107	8.522591	110	8.469486	108	5.864267845	76	4.589576878	60	4.587540478	60	0.830871358	-0.515541454	normal	0.154141279	-0.879274033	normal	0.228276126	-0.840278481	normal	0.053643484	-0.751594167	normal	[LR]	"Replication, recombination and repair;; General function prediction only"	Molecular Function: hydrolase activity (GO:0016787);; 	K17879|6.32684e-175|hsa:283927|NUDT7; nudix (nucleoside diphosphate linked moiety X)-type motif 7 (EC:3.6.1.-); K17879 peroxisomal coenzyme A diphosphatase NUDT7 [EC:3.6.1.-] (A)	Peroxisome (ko04146)	[L]	"Replication, recombination and repair"	NUDIX domain	Peroxisomal coenzyme A diphosphatase NUDT7 GN=NUDT7 OS=Homo sapiens (Human) PE=2 SV=1	L	"Replication, recombination and repair"	PREDICTED: peroxisomal coenzyme A diphosphatase NUDT7 [Leptonychotes weddellii]
ENSG00000140905(GCSH)	--	48.8814257	1033	54.53194	1146	60.532344	1258	52.359195	1131	48.8225098	1023	43.300176	915	0.976563915	0.099784548	normal	0.963593702	-0.18496894	normal	0.472634869	-0.466918692	normal	0.350283491	-0.184968547	normal	[E]	Amino acid transport and metabolism	--	"K02437|3.42178e-110|ptr:742399|GCSH; glycine cleavage system H protein, mitochondrial; K02437 glycine cleavage system H protein (A)"	"Glycine, serine and threonine metabolism (ko00260);; Glyoxylate and dicarboxylate metabolism (ko00630)"	[E]	Amino acid transport and metabolism	Glycine cleavage H-protein	"Glycine cleavage system H protein, mitochondrial (Precursor) GN=GCSH OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"glycine cleavage system H protein, mitochondrial precursor [Oryctolagus cuniculus] "
ENSG00000140931(CMTM3)	--	53.44673237	1410	65.33484587	1653	61.65177305	1554	82.42276207	2156	81.39691452	1968	87.39739144	2094	0.08664956	0.581314033	normal	0.961311863	0.230023872	normal	0.682720133	0.42162877	normal	0.006950638	0.408174234	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	CKLF-like MARVEL transmembrane domain-containing protein 3 GN=CMTM3 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: CKLF-like MARVEL transmembrane domain-containing protein 3 [Dasypus novemcinctus]
ENSG00000140932(CMTM2)	--	0.075921392	1	0	0	0.141656257	1	0.071798362	1	0.26313444	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	--	CKLF-like MARVEL transmembrane domain-containing protein 2 GN=CMTM2 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	"PREDICTED: CKLF-like MARVEL transmembrane domain-containing protein 2-like, partial [Tupaia chinensis]"
ENSG00000140937(CDH11)	--	0	0	0	0	0	0	0.075784755	4	0.083381985	6	0.526943157	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06803|0|hsa:1009|CDH11, CAD11, CDHOB, OB, OSF-4; cadherin 11, type 2, OB-cadherin (osteoblast); K06803 cadherin 11, type 2, OB-cadherin (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-11 (Precursor) GN=CDH11 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cadherin-11-like isoform 1 [Orcinus orca] 
ENSG00000140939(NOL3)	--	15.35686719	419	20.08522328	558	16.70355713	479	15.32828429	406	15.49332255	402	12.9267493	329	0.967297475	-0.076019571	normal	0.445127666	-0.492914657	normal	0.269949158	-0.54812884	normal	0.076583264	-0.378633398	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	--	--	--	--	Caspase recruitment domain	Nucleolar protein 3 GN=NOL3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: heat shock factor protein 4-like isoform X5 [Tupaia chinensis]
ENSG00000140941(MAP1LC3B)	--	35.52340036	1557	38.29580111	1670	36.62440077	1597	44.80640094	1993	40.727982	1779	46.15680094	2042	0.896683076	0.325056396	normal	0.983669873	0.069730665	normal	0.869981333	0.346036632	normal	0.149569153	0.248099489	normal	--	--	Biological Process: autophagic vacuole assembly (GO:0000045);; Cellular Component: cytoplasm (GO:0005737);; 	K10435|1.38076e-86|ptr:746157|MAP1LC3B; microtubule-associated protein 1 light chain 3 beta; K10435 microtubule-associated protein 1 light chain (A)	--	[Z]	Cytoskeleton	Autophagy protein Atg8 ubiquitin like;; Ubiquitin-like autophagy protein Apg12	Microtubule-associated proteins 1A/1B light chain 3B (Precursor) GN=MAP1LC3B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: microtubule-associated proteins 1A/1B light chain 3B [Myotis davidii] 
ENSG00000140943(MBTPS1)	--	44.8754251	3498	38.89107864	3341	37.6514684	3236	40.00333048	3260	43.00636992	3185	45.60348057	3411	0.987261102	-0.132430315	normal	0.988911405	-0.090371266	normal	0.990067395	0.067660904	normal	0.83770879	-0.052860583	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K08653|0|hsa:8720|MBTPS1, PCSK8, S1P, SKI-1; membrane-bound transcription factor peptidase, site 1 (EC:3.4.21.112); K08653 membrane-bound transcription factor site-1 protease [EC:3.4.21.112] (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family	Membrane-bound transcription factor site-1 protease (Precursor) GN=MBTPS1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: membrane-bound transcription factor site-1 protease [Loxodonta africana]
ENSG00000140948(ZCCHC14)	--	6.529635632	891	6.7528544	932	6.67690797	898	7.812319041	1046	8.608143	1156	9.456986	1290	0.957602951	0.200234329	normal	0.914780901	0.288891384	normal	0.279428892	0.513566857	normal	0.043119996	0.339331144	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[JT]	"Translation, ribosomal structure and biogenesis;; Signal transduction mechanisms"	SAM domain (Sterile alpha motif);; Zinc knuckle	Zinc finger CCHC domain-containing protein 14 GN=ZCCHC14 OS=Homo sapiens (Human) PE=2 SV=1	JOT	"Translation, ribosomal structure and biogenesis;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: zinc finger CCHC domain-containing protein 14 [Vicugna pacos]
ENSG00000140950(TLDC1)	--	16.01038021	1244	13.529918	935	17.73223466	1187	17.13910969	1376	13.75348709	967	11.73193345	844	0.977752093	0.114527195	normal	0.978213483	0.027079899	normal	0.335670485	-0.499537944	normal	0.843370735	-0.101405433	normal	--	--	--	--	--	--	--	TLD	TLD domain-containing protein 1 GN=TLDC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: TLD domain-containing protein KIAA1609 homolog [Ceratotherium simum simum]
ENSG00000140968(IRF8)	--	0	0	0.097442575	2	0	0	0.438287852	11	0.812999529	23	0.302014979	7	--	--	--	0.023127558	2.78687571	normal	--	--	--	--	--	--	--	--	"Molecular Function: regulatory region DNA binding (GO:0000975);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10155|0|hsa:3394|IRF8, H-ICSBP, ICSBP, ICSBP1, IMD32A, IMD32B, IRF-8; interferon regulatory factor 8; K10155 interferon regulatory factor 8 (A)"	Pertussis (ko05133)	--	--	Interferon-regulatory factor 3;; Interferon regulatory factor transcription factor	Interferon regulatory factor 8 GN=IRF8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: interferon regulatory factor 8 isoform X2 [Pteropus alecto] 
ENSG00000140983(RHOT2)	--	26.906538	1263	20.47796866	1004	24.39150083	1207	28.22494459	1337	30.18321603	1431	23.29026855	1120	0.98162832	0.051251963	normal	0.401497487	0.489217665	normal	0.976099578	-0.116067379	normal	0.553656808	0.140972526	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07871|0|hsa:89941|RHOT2, ARHT2, C16orf39, MIRO-2, MIRO2, RASL; ras homolog family member T2 (EC:3.6.5.-); K07871 Ras homolog gene family, member T2 (A)"	--	[V]	Defense mechanisms	EF hand associated;; Miro-like protein;; EF hand associated;; Ras family;; 50S ribosome-binding GTPase;; ADP-ribosylation factor family	Mitochondrial Rho GTPase 2 GN=RHOT2 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: mitochondrial Rho GTPase 2 isoform X2 [Pteropus alecto]
ENSG00000140986(RPL3L)	--	0.150576352	6	0.291204194	12	0.215744826	8	0.074494341	3	0.097357429	3	0.07450832	3	--	--	--	--	--	--	--	--	--	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02925|0|pps:100996026|RPL3L; ribosomal protein L3-like; K02925 large subunit ribosomal protein L3e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L3	60S ribosomal protein L3-like GN=RPL3L OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	60S ribosomal protein L3-like [Bos taurus] 
ENSG00000140987(ZSCAN32)	--	4.692587661	295	4.93047535	259	5.308404919	316	6.65343088	351	6.568216002	407	5.520968653	261	0.939801123	0.218877755	normal	0.123249141	0.627703339	normal	0.91155784	-0.282675284	normal	0.55926066	0.206487158	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:54925|ZSCAN32, HCCS-5, ZNF434; zinc finger and SCAN domain containing 32; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Myb/SANT-like DNA-binding domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger and SCAN domain-containing protein 32 GN=ZSCAN32 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger and SCAN domain-containing protein 32 [Balaenoptera acutorostrata scammoni]
ENSG00000140988(RPS2)	--	2264.578678	32717	2002.286993	29993	2127.957591	31871	2805.742175	41596	2702.17395	39041	2626.201361	38385	0.989650575	0.315558903	normal	0.980118561	0.358921714	normal	0.99442884	0.259995663	normal	0.149569153	0.31020959	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02981|9.09896e-175|mcc:700955|40S ribosomal protein S2-like; K02981 small subunit ribosomal protein S2e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein S5, N-terminal domain;; Ribosomal protein S5, C-terminal domain"	40S ribosomal protein S2 GN=RPS2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: ribosomal protein S2 [Balaenoptera acutorostrata scammoni]
ENSG00000140990(NDUFB10)	--	130.19145	1394	119.546851	1305	132.17393	1503	114.9591154	1320	117.4328945	1313	114.101251	1303	0.978699434	-0.109400956	normal	0.982129272	-0.012594898	normal	0.96087991	-0.214067825	normal	0.59683371	-0.115360057	normal	--	--	--	"K03966|1.86041e-104|hsa:4716|NDUFB10, PDSW; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa; K03966 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 10 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	NADH-ubiquinone oxidoreductase subunit 10	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 GN=NDUFB10 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 [Galeopterus variegatus]
ENSG00000140992(PDPK1)	--	11.36247042	1464	11.69883	1560	12.61694871	1664	13.23576514	1742	11.70733994	1547	13.29758508	1762	0.961761483	0.219785153	normal	0.983693824	-0.033466811	normal	0.983782071	0.074201508	normal	0.711368628	0.08654879	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06276|0|cjc:100389944|PDPK1; 3-phosphoinositide dependent protein kinase 1; K06276 3-phosphoinositide dependent protein kinase-1 [EC:2.7.11.1] (A)	PPAR signaling pathway (ko03320);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Focal adhesion (ko04510);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Thyroid hormone signaling pathway (ko04919);; Aldosterone-regulated sodium reabsorption (ko04960);; Toxoplasmosis (ko05145);; Hepatitis C (ko05160);; Proteoglycans in cancer (ko05205);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; PH domain;; Protein tyrosine kinase;; Kinase-like	3-phosphoinositide-dependent protein kinase 1 GN=PDPK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 3-phosphoinositide-dependent protein kinase 1 isoform X1 [Lipotes vexillifer]
ENSG00000140993(TIGD7)	--	1.533967295	100	1.872874064	124	1.57474	102	2.380080005	159	1.821137	85	2.32119	153	0.467570186	0.63045158	normal	0.730528566	-0.557961846	normal	0.630649252	0.569729236	normal	0.623059952	0.262465824	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; Tc5 transposase DNA-binding domain;; CENP-B N-terminal DNA-binding domain	Tigger transposable element-derived protein 7 GN=TIGD7 OS=Homo sapiens (Human) PE=2 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: tigger transposable element-derived protein 7 [Ceratotherium simum simum]
ENSG00000140995(DEF8)	--	40.6713793	1100	48.43355396	1101	48.98670486	1238	45.94954371	1190	46.19666909	1206	49.4036212	1318	0.97857445	0.082514965	normal	0.976121502	0.109844689	normal	0.980021756	0.081950579	normal	0.705945714	0.090311214	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4206);; Phorbol esters/diacylglycerol binding domain (C1 domain)	Differentially expressed in FDCP 8 homolog GN=DEF8 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: differentially expressed in FDCP 8 homolog isoform X2 [Mustela putorius furo] 
ENSG00000141002(TCF25)	--	26.73344984	1138	27.23050861	1161	23.40055919	1116	22.20086164	1003	26.37528132	1176	25.65155328	1151	0.955640064	-0.212705053	normal	0.980896218	-0.002902713	normal	0.98058132	0.036211045	normal	0.828193378	-0.057153154	normal	--	--	--	--	--	[S]	Function unknown	Transcriptional repressor TCF25	Transcription factor 25 GN=TCF25 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor 25 isoform X2 [Equus przewalskii]
ENSG00000141012(GALNS)	--	32.63021601	1511	37.195074	1755	30.41830219	1463	16.24706448	764	16.75373968	781	26.06377125	1197	3.74E-07	-1.01321257	down	6.55E-10	-1.187924985	down	0.913782113	-0.297457528	normal	0.000578709	-0.806378335	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K01132|0|hsa:2588|GALNS, GALNAC6S, GAS, GalN6S, MPS4A; galactosamine (N-acetyl)-6-sulfatase (EC:3.1.6.4); K01132 N-acetylgalactosamine-6-sulfatase [EC:3.1.6.4] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	[R]	General function prediction only	Sulfatase;; C-terminal region of aryl-sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	N-acetylgalactosamine-6-sulfatase (Precursor) GN=GALNS OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: N-acetylgalactosamine-6-sulfatase isoform X1 [Equus przewalskii]
ENSG00000141013(GAS8)	--	9.83731807	616	9.337405025	564	8.3635897	662	7.7045624	539	9.937966	605	8.909674	539	0.94118121	-0.222882467	normal	0.969890344	0.079607305	normal	0.888491721	-0.304066161	normal	0.542395782	-0.151136252	normal	--	--	Cellular Component: motile cilium (GO:0031514);; Biological Process: cell motility (GO:0048870);; 	--	--	--	--	Growth-arrest specific micro-tubule binding	Growth arrest-specific protein 8 GN=GAS8 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: growth arrest-specific protein 8 isoform X2 [Oryctolagus cuniculus]
ENSG00000141026(MED9)	--	12.14513141	429	9.90177987	363	9.74555033	363	11.24241673	405	13.4626794	486	10.7167153	390	0.96381723	-0.113469655	normal	0.75195083	0.398122253	normal	0.965134361	0.09483191	normal	0.668074155	0.128071461	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C5orf17 GN=C5orf17 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: T-box transcription factor TBX1 [Condylura cristata]
ENSG00000141027(NCOR1)	--	48.42951946	5771	49.57704062	5465	44.87741176	5847	39.4939252	4742	37.61225083	4791	47.17362918	5172	0.952407775	-0.31406551	normal	0.983700061	-0.211258749	normal	0.987559627	-0.185214789	normal	0.189784829	-0.237104717	normal	--	--	--	K04650|0|ptr:468370|NCOR1; nuclear receptor corepressor 1; K04650 nuclear receptor co-repressor 1 (A)	Thyroid hormone signaling pathway (ko04919);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Myb-like DNA-binding domain	Nuclear receptor corepressor 1 GN=NCOR1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor corepressor 1 isoform 1 [Ceratotherium simum simum]
ENSG00000141030(COPS3)	--	74.69399473	1917	75.46083129	1929	77.90387192	1983	81.619658	2106	81.85485155	2110	67.41711293	1750	0.983783209	0.104742727	normal	0.983302931	0.107882413	normal	0.972650771	-0.188468089	normal	0.971576238	0.011883453	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12177|0|tup:102503187|COPS3; COP9 signalosome subunit 3; K12177 COP9 signalosome complex subunit 3 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PCI domain	COP9 signalosome complex subunit 3 GN=COPS3 OS=Homo sapiens (Human) PE=1 SV=3	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: COP9 signalosome complex subunit 3-like [Elephantulus edwardii]
ENSG00000141034(GID4)	--	7.079455432	493	7.816410453	545	9.508411742	636	7.929387	555	8.341819068	577	9.399880322	634	0.962293591	0.1396575	normal	0.97064927	0.060724761	normal	0.974318726	-0.012804872	normal	0.861169441	0.056752179	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar import and degradation protein	Glucose-induced degradation protein 4 homolog GN=GID4 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: glucose-induced degradation protein 4 homolog [Odobenus rosmarus divergens]
ENSG00000141040(ZNF287)	--	5.438928444	286	4.499001031	277	5.223119102	255	3.973499859	234	3.568562677	199	3.648752968	202	0.889428998	-0.318443811	normal	0.595530091	-0.495337913	normal	0.876451676	-0.342148225	normal	0.158951343	-0.387202514	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:57336|ZNF287, ZKSCAN13, ZSCAN45; zinc finger protein 287; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; SCAN domain;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; BED zinc finger"	Zinc finger protein 287 GN=ZNF287 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 287 [Ceratotherium simum simum]
ENSG00000141052(MYOCD)	--	0.13300243	20	0.067451409	11	0.024341394	3	0.136262126	23	0.3243789	52	0.119102848	16	0.987769446	0.159378777	normal	0.000505988	2.076695979	up	--	--	--	0.291560065	1.397169317	normal	--	--	--	--	--	--	--	RPEL repeat;; SAP domain	Myocardin GN=MYOCD OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myocardin isoform X2 [Tupaia chinensis]
ENSG00000141068(KSR1)	--	8.3692662	792	9.307642534	734	9.67142743	734	10.88849214	988	12.22086416	1023	17.08809417	1081	0.909958243	0.287677868	normal	0.535756902	0.456727221	normal	0.169147586	0.549284925	normal	0.008235451	0.431250376	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K14958|0|mcc:706388|KSR1; kinase suppressor of ras 1; K14958 kinase suppressor of Ras 1 (A)	Ras signaling pathway (ko04014);; Tuberculosis (ko05152)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SAM like domain present in kinase suppressor RAS 1;; Kinase-like	Kinase suppressor of Ras 1 GN=KSR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: kinase suppressor of Ras 1 [Ceratotherium simum simum]
ENSG00000141076(UTP4)	--	49.56155043	1863	45.889123	1726	48.666422	1805	51.080977	1784	43.639585	1662	40.6512765	1536	0.98343497	-0.093265709	normal	0.983205353	-0.07587089	normal	0.955330401	-0.240893021	normal	0.510321905	-0.136244403	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14548|0|hsa:84916|CIRH1A, CIRHIN, NAIC, TEX292, UTP4; cirrhosis, autosomal recessive 1A (cirhin); K14548 U3 small nucleolar RNA-associated protein 4 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	"WD domain, G-beta repeat"	Cirhin GN=CIRH1A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cirhin [Ceratotherium simum simum]
ENSG00000141084(RANBP10)	--	5.34572215	527	5.638125833	568	5.583569651	569	5.854497867	611	5.677508261	589	5.933122818	609	0.954397805	0.182043935	normal	0.972218605	0.030869436	normal	0.96990593	0.089492189	normal	0.721808438	0.099378794	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	CTLH/CRA C-terminal to LisH motif domain;; SPRY domain;; LisH	Ran-binding protein 10 GN=RANBP10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ran-binding protein 10 isoform X1 [Camelus ferus] 
ENSG00000141086(CTRL)	--	0.896857	26	1.258357	32	1.03988	30	0.692753808	17	1.07225	31	0.477926	14	0.972404278	-0.599671475	normal	0.983149093	-0.064149905	normal	0.862805684	-1.030191352	normal	0.48846016	-0.52647207	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09632|6.67942e-166|hsa:1506|CTRL, CTRL1; chymotrypsin-like (EC:3.4.21.-); K09632 chymotrypsin-like protease [EC:3.4.21.-] (A)"	Pancreatic secretion (ko04972);; Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Chymotrypsin-like protease CTRL-1 (Precursor) GN=CTRL OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: chymotrypsin-like protease CTRL-1 [Orycteropus afer afer]
ENSG00000141098(GFOD2)	--	8.883433	501	9.444875052	536	11.08146991	555	10.23229588	518	11.01517509	549	9.924234894	506	0.971790309	0.017257185	normal	0.971846163	0.013110043	normal	0.962336489	-0.141238612	normal	0.910252232	-0.03843179	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; 	--	--	[R]	General function prediction only	"Oxidoreductase family, NAD-binding Rossmann fold"	Glucose-fructose oxidoreductase domain-containing protein 2 (Precursor) GN=GFOD2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: glucose-fructose oxidoreductase domain-containing protein 2 isoform X1 [Canis lupus familiaris] 
ENSG00000141101(NOB1)	--	46.941	1647	43.9952	1543	39.94	1413	41.0727	1448	40.7432	1424	39.2106	1386	0.962105428	-0.216395726	normal	0.976751369	-0.137075576	normal	0.982938136	-0.036086653	normal	0.523249156	-0.133912127	normal	[R]	General function prediction only	--	"K11883|0|hsa:28987|NOB1, ART-4, MST158, NOB1P, PSMD8BP1; NIN1/RPN12 binding protein 1 homolog (S. cerevisiae); K11883 RNA-binding protein NOB1 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[O]	"Posttranslational modification, protein turnover, chaperones"	Drug resistance and apoptosis regulator;; Nin one binding (NOB1) Zn-ribbon like	RNA-binding protein NOB1 GN=NOB1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RNA-binding protein NOB1 [Felis catus]
ENSG00000141127(PRPSAP2)	--	26.91366778	785	31.6028507	867	29.4501074	817	30.8706673	880	25.95837244	735	27.6433572	793	0.969170701	0.133731312	normal	0.928771906	-0.259222571	normal	0.976041392	-0.051210434	normal	0.84006498	-0.05771067	normal	[FE]	Nucleotide transport and metabolism;; Amino acid transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: ribose phosphate diphosphokinase activity (GO:0004749);; Biological Process: nucleoside metabolic process (GO:0009116);; Biological Process: nucleotide biosynthetic process (GO:0009165);; 	--	--	[EF]	Amino acid transport and metabolism;; Nucleotide transport and metabolism	Phosphoribosyl synthetase-associated domain;; N-terminal domain of ribose phosphate pyrophosphokinase	Phosphoribosyl pyrophosphate synthase-associated protein 2 GN=PRPSAP2 OS=Homo sapiens (Human) PE=1 SV=1	EF	Amino acid transport and metabolism;; Nucleotide transport and metabolism	PREDICTED: phosphoribosyl pyrophosphate synthase-associated protein 2 [Ursus maritimus]
ENSG00000141161(UNC45B)	--	0	0	0	0	0	0	0.017587853	1	0.018394655	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[ODR]	"Posttranslational modification, protein turnover, chaperones;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Myosin-binding striated muscle assembly central;; TPR repeat;; HEAT repeats;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Armadillo/beta-catenin-like repeat	Protein unc-45 homolog B GN=UNC45B OS=Homo sapiens (Human) PE=1 SV=1	DO	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein unc-45 homolog B isoform X3 [Canis lupus familiaris] 
ENSG00000141179(PCTP)	--	14.326683	517	11.759536	431	11.76254	439	13.86468	505	14.068469	509	13.555518	493	0.970075651	-0.064519141	normal	0.940698084	0.217847201	normal	0.957835388	0.158559575	normal	0.739936328	0.098367541	normal	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[I]	Lipid transport and metabolism	START domain	Phosphatidylcholine transfer protein GN=PCTP OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: phosphatidylcholine transfer protein isoform X1 [Condylura cristata]
ENSG00000141198(TOM1L1)	--	34.68117601	949	34.352632	999	31.78026707	865	29.47674903	903	29.8942451	916	27.1452156	896	0.974304942	-0.102344468	normal	0.968980314	-0.146332208	normal	0.977440475	0.042434262	normal	0.782875373	-0.072575694	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: intracellular protein transport (GO:0006886);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	VHS domain;; GAT domain	TOM1-like protein 1 GN=TOM1L1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: target of myb1 (chicken)-like 1 [Equus caballus] 
ENSG00000141219(C17orf80)	--	9.36447176	647	9.5922178	675	9.507177076	665	9.948062622	705	9.5994146	670	10.062773	686	0.971122042	0.092814106	normal	0.973933658	-0.032080822	normal	0.974523607	0.036481109	normal	0.924184328	0.031467016	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C17orf80 GN=C17orf80 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C17orf80 homolog isoform X3 [Galeopterus variegatus]
ENSG00000141232(TOB1)	--	112.4742677	3658	119.7278521	3873	92.4499495	2968	43.75064422	1422	43.12454286	1402	61.8602199	2013	3.89E-15	-1.392990615	down	1.11E-16	-1.486383856	down	0.119865515	-0.568081616	normal	2.70E-07	-1.138650445	down	--	--	--	"K14443|0|ptr:468406|TOB1; transducer of ERBB2, 1; K14443 protein Tob/BTG (A)"	RNA degradation (ko03018)	[TR]	Signal transduction mechanisms;; General function prediction only	BTG family;; Ataxin-2 C-terminal region	Protein Tob1 GN=TOB1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein Tob1 [Pteropus alecto] 
ENSG00000141252(VPS53)	--	9.176795	1448	11.45853357	1632	12.86272417	1664	14.57265862	2134	14.60999754	1991	13.49477	1938	0.229086278	0.528202069	normal	0.946887014	0.265202805	normal	0.966682504	0.211443473	normal	0.036334145	0.332551714	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Vps53-like, N-terminal;; Protein of unknown function N-terminal domain (DUF2450)"	Vacuolar protein sorting-associated protein 53 homolog GN=VPS53 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 53 homolog [Leptonychotes weddellii]
ENSG00000141255(SPATA22)	--	0.201996526	23	0.18169886	21	0.18002456	20	0.170338494	19	0.179117229	20	0.183145333	21	0.986224321	-0.285453105	normal	0.987672176	-0.085505502	normal	0.988474233	0.057830205	normal	0.93492335	-0.114136545	normal	--	--	--	--	--	--	--	--	Spermatogenesis-associated protein 22 GN=SPATA22 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: spermatogenesis-associated protein 22 isoform X1 [Galeopterus variegatus]
ENSG00000141258(SGSM2)	--	22.8402813	2177	21.58053871	1891	19.10573834	1929	18.3561807	1712	19.56822658	1833	17.57849631	1680	0.815263845	-0.377189934	normal	0.984629455	-0.066315265	normal	0.967757658	-0.207508882	normal	0.214673933	-0.220075467	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	RUN domain;; Rab-GTPase-TBC domain	Small G protein signaling modulator 2 GN=SGSM2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: small G protein signaling modulator 2 isoform 1 [Ceratotherium simum simum]
ENSG00000141279(NPEPPS)	--	85.07130563	5251	76.73389842	5330	83.24880248	5380	80.15757312	5632	70.52758048	4654	77.34656449	5149	0.993200558	0.070203039	normal	0.982531399	-0.217024922	normal	0.992963173	-0.071584774	normal	0.783669322	-0.069861275	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	K08776|0|ptr:749281|NPEPPS; aminopeptidase puromycin sensitive; K08776 puromycin-sensitive aminopeptidase [EC:3.4.11.-] (A)	--	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	Puromycin-sensitive aminopeptidase GN=NPEPPS OS=Homo sapiens (Human) PE=1 SV=2	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: puromycin-sensitive aminopeptidase isoform X1 [Oryctolagus cuniculus]
ENSG00000141293(SKAP1)	--	0	0	0	0	0	0	0.044576908	1	0.069622039	1	0.044635601	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K17699|0|pps:100989898|SKAP1; src kinase associated phosphoprotein 1; K17699 src kinase associated phosphoprotein 1 (A)	Rap1 signaling pathway (ko04015)	--	--	PH domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Pleckstrin homology domain	Src kinase-associated phosphoprotein 1 GN=SKAP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: src kinase-associated phosphoprotein 1 isoform X1 [Tupaia chinensis]
ENSG00000141294(LRRC46)	--	1.21518	43	0.789001	28	1.70912	61	0.452007	16	0.881346	31	0.978213	35	0.205118814	-1.37357867	normal	0.983405763	0.119290045	normal	0.740026548	-0.783777168	normal	0.313585257	-0.704695146	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine rich repeat;; Leucine Rich Repeat	Leucine-rich repeat-containing protein 46 GN=LRRC46 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 46 [Physeter catodon]
ENSG00000141295(SCRN2)	--	25.4145626	719	23.08986197	713	24.77742076	739	16.268791	481	19.095849	537	15.8813978	477	0.074203408	-0.609183765	normal	0.64390824	-0.429353354	normal	0.042585175	-0.638237576	normal	0.001161482	-0.559306791	normal	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: dipeptidase activity (GO:0016805);; 	K14358|0|pps:100984172|SCRN2; secernin 2; K14358 secernin (A)	--	--	--	Peptidase family C69;; Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase	Secernin-2 GN=SCRN2 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: secernin-2 [Pteropus alecto] 
ENSG00000141298(SSH2)	--	24.33620236	904	21.58525752	836	19.45209681	787	16.35475759	985	18.50279433	1086	15.27020581	798	0.975375498	0.09281754	normal	0.830170161	0.355457123	normal	0.976866671	0.01171132	normal	0.49837855	0.161282011	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K05766|0|hsa:85464|SSH2, SSH-2, SSH-2L; slingshot protein phosphatase 2 (EC:3.1.3.16 3.1.3.48); K05766 protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48] (A)"	Regulation of actin cytoskeleton (ko04810)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; DEK C terminal domain"	Protein phosphatase Slingshot homolog 2 GN=SSH2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: protein phosphatase Slingshot homolog 2 isoform 1 [Trichechus manatus latirostris]
ENSG00000141314(RHBDL3)	--	2.068864352	167	1.361698545	129	2.363969232	206	1.259918004	71	2.28685167	154	1.458205577	72	9.98E-05	-1.24664748	down	0.946159182	0.231644692	normal	1.02E-07	-1.505315378	down	0.147841843	-0.777295336	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K02857|0|pps:100995298|RHBDL3; rhomboid, veinlet-like 3 (Drosophila); K02857 rhomboid-related protein 1/2/3 [EC:3.4.21.105] (A)"	--	[T]	Signal transduction mechanisms	Rhomboid family;; EF-hand domain pair;; Rhomboid family	Rhomboid-related protein 3 GN=RHBDL3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: rhomboid-related protein 3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000141337(ARSG)	--	4.801409003	169	1.9908931	121	2.064571904	108	2.346589875	72	2.982710862	94	2.0980116	101	9.53E-05	-1.243919669	down	0.906504914	-0.380292888	normal	0.967844953	-0.103468939	normal	0.111443173	-0.59649918	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	K12381|0|hsa:22901|ARSG; arylsulfatase G; K12381 arylsulfatase G [EC:3.1.6.-] (A)	Lysosome (ko04142)	[R]	General function prediction only	Sulfatase;; C-terminal region of aryl-sulfatase	Arylsulfatase G (Precursor) GN=ARSG OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: arylsulfatase G [Galeopterus variegatus]
ENSG00000141338(ABCA8)	--	0.154033297	15	0.111571959	11	0.148723172	8	0.275672012	25	0.48078765	48	0.355593071	36	0.971529474	0.653817917	normal	0.00247326	1.964636842	up	0.024163882	1.972033819	normal	0.004081985	1.659985951	up	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05650|0|hsa:10351|ABCA8; ATP-binding cassette, sub-family A (ABC1), member 8; K05650 ATP-binding cassette, subfamily A (ABC1), member 8 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	"ABC transporter;; ABC-2 family transporter protein;; AAA domain;; Protein of unknown function, DUF258;; P-loop containing region of AAA domain"	ATP-binding cassette sub-family A member 8 GN=ABCA8 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family A member 8 [Equus caballus]
ENSG00000141349(G6PC3)	--	93.232793	1723	85.510846	1554	88.129431	1702	109.803435	2064	101.727755	1841	103.193735	1901	0.962271169	0.229500831	normal	0.962164062	0.2228771	normal	0.978080085	0.151108951	normal	0.271403374	0.200300069	normal	--	--	--	"K01084|0|hsa:92579|G6PC3, SCN4, UGRP; glucose 6 phosphatase, catalytic, 3 (EC:3.1.3.9); K01084 glucose-6-phosphatase [EC:3.1.3.9] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Carbohydrate digestion and absorption (ko04973)	--	--	PAP2 superfamily	Glucose-6-phosphatase 3 GN=G6PC3 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: glucose-6-phosphatase 3 [Tupaia chinensis]
ENSG00000141367(CLTC)	--	201.0435377	21196	201.5776034	21340	208.7751156	21617	206.4893516	22003	203.2534446	21058	191.784087	20495	0.998032023	0.023074304	normal	0.997838366	-0.040615415	normal	0.997645409	-0.085179652	normal	0.913836245	-0.034867178	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: clathrin coat of trans-Golgi network vesicle (GO:0030130);; Cellular Component: clathrin coat of coated pit (GO:0030132);; 	"K04646|0|hsa:1213|CLTC, CHC, CHC17, CLH-17, CLTCL2, Hc; clathrin, heavy chain (Hc); K04646 clathrin heavy chain (A)"	Lysosome (ko04142);; Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016);; Bacterial invasion of epithelial cells (ko05100)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Region in Clathrin and VPS;; Clathrin propeller repeat;; Clathrin-H-link;; Clathrin, heavy-chain linker;; Coatomer WD associated region;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Clathrin heavy chain 1 GN=CLTC OS=Homo sapiens (Human) PE=1 SV=5	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: clathrin heavy chain 1 isoform X1 [Eptesicus fuscus] 
ENSG00000141371(C17orf64)	--	0.169112	2	0.930691	2	0.0792191	0	0.160058	2	0.081996	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Domain of unknown function (DUF4208)	Uncharacterized protein C17orf64 GN=C17orf64 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: uncharacterized protein C17orf64 homolog [Loxodonta africana]
ENSG00000141376(BCAS3)	--	12.14077088	740	12.96520732	649	11.8840066	725	7.3950388	493	10.2574149	647	9.017690877	591	0.064682861	-0.615193149	normal	0.973650536	-0.025819069	normal	0.891053496	-0.302414356	normal	0.113326625	-0.30884025	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"Breast carcinoma amplified sequence 3;; WD domain, G-beta repeat"	"Breast carcinoma-amplified sequence 3 {ECO:0000312|HGNC:HGNC:14347, ECO:0000312|MIM:607470} OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	PREDICTED: breast carcinoma-amplified sequence 3 isoform X1 [Condylura cristata]
ENSG00000141378(PTRH2)	--	44.46486	853	47.687479	940	44.955897	855	50.73011	965	52.73904	1030	40.87037	799	0.968442911	0.146902063	normal	0.973921989	0.110315534	normal	0.972572906	-0.105826686	normal	0.839429159	0.055673906	normal	[S]	Function unknown	Molecular Function: aminoacyl-tRNA hydrolase activity (GO:0004045);; 	"K04794|2.20532e-129|pps:103785900|PTRH2; peptidyl-tRNA hydrolase 2; K04794 peptidyl-tRNA hydrolase, PTH2 family [EC:3.1.1.29] (A)"	--	[S]	Function unknown	Peptidyl-tRNA hydrolase PTH2	"Peptidyl-tRNA hydrolase 2, mitochondrial (Precursor) GN=PTRH2 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: peptidyl-tRNA hydrolase 2, mitochondrial [Eptesicus fuscus]"
ENSG00000141380(SS18)	--	25.14127911	1463	28.55548228	1690	24.6476271	1421	26.39422999	1589	26.86536926	1535	26.13433852	1528	0.981688993	0.088268133	normal	0.974943897	-0.160060788	normal	0.980798505	0.096347647	normal	0.995749588	0.002868661	normal	--	--	Molecular Function: transcription coactivator activity (GO:0003713);; 	"K15623|8.76103e-138|hsa:6760|SS18, SSXT, SYT; synovial sarcoma translocation, chromosome 18; K15623 protein SSXT (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	SSXT protein (N-terminal region)	Protein SSXT GN=SS18 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	"PREDICTED: protein SSXT, partial [Galeopterus variegatus]"
ENSG00000141384(TAF4B)	--	2.215336505	215	2.191820611	216	1.314808521	129	1.509129688	150	1.611182098	151	1.542838348	154	0.53702775	-0.545511536	normal	0.573438172	-0.53341726	normal	0.944794392	0.244639845	normal	0.426308471	-0.321497727	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor TFIID complex (GO:0005669);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K03129|0|hsa:6875|TAF4B, SPGF13, TAF2C2, TAFII105; TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa; K03129 transcription initiation factor TFIID subunit 4 (A)"	Basal transcription factors (ko03022);; Huntington's disease (ko05016);; Herpes simplex infection (ko05168)	[K]	Transcription	Transcription initiation factor TFIID component TAF4 family;; NHR1 homology to TAF	Transcription initiation factor TFIID subunit 4B GN=TAF4B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 4B [Ceratotherium simum simum]
ENSG00000141385(AFG3L2)	--	19.829154	1221	23.98337054	1283	21.328217	1200	23.48651	1353	24.693071	1286	21.89452	1138	0.977263999	0.11712633	normal	0.981864	-0.018035852	normal	0.978763046	-0.084715643	normal	0.985884899	0.006380335	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metalloendopeptidase activity (GO:0004222);; Molecular Function: ATP binding (GO:0005524);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08956|0|hsa:10939|AFG3L2, SCA28, SPAX5; AFG3-like AAA ATPase 2; K08956 AFG3 family protein [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M41;; ATPase family associated with various cellular activities (AAA);; FtsH Extracellular	AFG3-like protein 2 GN=AFG3L2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: AFG3-like protein 2 [Ceratotherium simum simum]
ENSG00000141391(PRELID3A)	--	3.915649504	94	4.531197	133	3.18806413	85	3.524784873	107	4.286492487	111	5.027954119	127	0.965283569	0.15369029	normal	0.93859205	-0.278817514	normal	0.721037575	0.562759154	normal	0.829495962	0.123802087	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PRELI-like family	Protein slowmo homolog 1 GN=SLMO1 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein slowmo homolog 1 isoform X10 [Equus przewalskii]
ENSG00000141401(IMPA2)	--	36.33029494	879	37.31037087	879	31.16323209	758	22.9297776	522	27.31860003	630	28.09718603	648	0.001262494	-0.780852831	normal	0.364231543	-0.500914833	normal	0.939465772	-0.233990021	normal	0.002550666	-0.503898932	normal	[G]	Carbohydrate transport and metabolism	Biological Process: phosphatidylinositol phosphorylation (GO:0046854);; 	K01092|0|hsa:3613|IMPA2; inositol(myo)-1(or 4)-monophosphatase 2 (EC:3.1.3.25); K01092 myo-inositol-1(or 4)-monophosphatase [EC:3.1.3.25] (A)	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[G]	Carbohydrate transport and metabolism	Inositol monophosphatase family	Inositol monophosphatase 2 GN=IMPA2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: inositol monophosphatase 2 [Odobenus rosmarus divergens]
ENSG00000141404(GNAL)	--	8.721571557	556	12.21381224	629	13.9831	616	3.617466	191	5.8454703	251	4.115207542	265	1.43E-13	-1.564601152	down	2.61E-10	-1.341507588	down	1.11E-08	-1.220523556	down	9.87E-15	-1.369148432	down	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04633|0|nle:100597944|GNAL; guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type; K04633 guanine nucleotide-binding protein G(olf) subunit alpha (A)"	Calcium signaling pathway (ko04020);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Parkinson's disease (ko05012);; Chagas disease (American trypanosomiasis) (ko05142);; Amoebiasis (ko05146)	[T]	Signal transduction mechanisms	G-protein alpha subunit;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Guanine nucleotide-binding protein G(olf) subunit alpha GN=GNAL OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(olf) subunit alpha isoform X1 [Oryctolagus cuniculus]
ENSG00000141424(SLC39A6)	--	31.83008168	1786	29.810611	1746	31.46616782	1754	30.96180192	1723	29.53184	1685	30.81876843	1743	0.983609111	-0.082569316	normal	0.983492016	-0.072667451	normal	0.985535719	-0.017352612	normal	0.817737445	-0.058494199	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14712|0|ptr:468523|SLC39A6; solute carrier family 39 (zinc transporter), member 6; K14712 solute carrier family 39 (zinc transporter), member 6 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP6 (Precursor) GN=SLC39A6 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP6 isoform 1 [Ceratotherium simum simum]
ENSG00000141425(RPRD1A)	--	20.34357102	1280	20.05772076	1243	20.73291243	1253	20.0680965	1257	17.82836764	1067	20.24976743	1203	0.981142818	-0.056922473	normal	0.946396725	-0.241375353	normal	0.980371309	-0.06695873	normal	0.584775034	-0.119817037	normal	--	--	--	--	--	[A]	RNA processing and modification	RNA polymerase II-binding domain.	Regulation of nuclear pre-mRNA domain-containing protein 1A GN=RPRD1A OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: regulation of nuclear pre-mRNA domain-containing protein 1A isoform X2 [Oryctolagus cuniculus]
ENSG00000141428(C18orf21)	--	8.842919441	179	8.875123554	175	8.702535672	174	8.060501047	155	8.2421891	159	9.976487989	186	0.942937506	-0.236341234	normal	0.956572945	-0.15831871	normal	0.964438664	0.087190815	normal	0.835100739	-0.09928625	normal	--	--	--	--	--	--	--	--	UPF0711 protein C18orf21 GN=C18orf21 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0711 protein C18orf21 homolog isoform X1 [Galeopterus variegatus]
ENSG00000141429(GALNT1)	--	39.11387	2331	43.25926	2486	44.42406992	2340	109.45259	5240	94.9857	5242	94.9459	4936	6.50E-10	1.137272544	up	4.33E-08	1.054412895	up	1.28E-08	1.068056234	up	7.86E-16	1.085773324	up	--	--	--	K00710|0|ptr:468521|GALNT1; polypeptide N-acetylgalactosaminyltransferase 1; K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 1 soluble form GN=GALNT1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 1 isoform X2 [Galeopterus variegatus]
ENSG00000141434(MEP1B)	--	0.02444051	1	0	0	0	0	0.02421732	1	0.0473795	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K08606|0|hsa:4225|MEP1B; meprin A, beta (EC:3.4.24.63); K08606 meprin B [EC:3.4.24.63] (A)"	Protein digestion and absorption (ko04974)	[O]	"Posttranslational modification, protein turnover, chaperones"	Astacin (Peptidase family M12A);; MAM domain;; MATH domain	Meprin A subunit beta (Precursor) GN=MEP1B OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: meprin A subunit beta [Equus przewalskii]
ENSG00000141441(GAREM1)	--	1.712060047	137	1.476292044	148	1.4771065	179	1.1344906	137	1.5838105	181	1.739457126	222	0.968171302	-0.030490322	normal	0.932563569	0.266500108	normal	0.912792584	0.300028438	normal	0.65346163	0.199503806	normal	--	--	--	--	--	--	--	"Cell-cycle sustaining, positive selection,"	GRB2-associated and regulator of MAPK protein GN=GAREM OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: GRB2-associated and regulator of MAPK protein [Ceratotherium simum simum]
ENSG00000141446(ESCO1)	--	4.963213533	393	6.065562927	525	5.741002401	491	5.379043088	448	5.639656196	491	7.115011633	589	0.956990111	0.157559953	normal	0.964509996	-0.117670374	normal	0.925984094	0.253539266	normal	0.782702731	0.096670073	normal	--	--	--	"K11268|0|hsa:114799|ESCO1, A930014I12Rik, CTF, ECO1, EFO1, ESO1; establishment of sister chromatid cohesion N-acetyltransferase 1; K11268 N-acetyltransferase [EC:2.3.1.-] (A)"	--	--	--	ESCO1/2 acetyl-transferase;; zinc-finger of acetyl-transferase ESCO	N-acetyltransferase ESCO1 GN=ESCO1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: N-acetyltransferase ESCO1 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000141447(OSBPL1A)	--	9.423992231	613	9.85382279	665	9.6705585	548	8.96775956	519	8.194043901	475	9.850937127	576	0.915653386	-0.2702476	normal	0.3738387	-0.505486304	normal	0.97126152	0.063430724	normal	0.273453308	-0.239128411	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Oxysterol-binding protein;; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Oxysterol-binding protein-related protein 1 GN=OSBPL1A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 1 isoform X1 [Camelus ferus] 
ENSG00000141448(GATA6)	--	1.018280802	53	0.52755485	28	0.78687376	34	3.730684	175	3.25467337	158	3.20895106	161	3.68E-08	1.664409121	up	1.61E-13	2.41350388	up	4.91E-12	2.186082262	up	9.28E-11	2.081236012	up	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	K17897|0|hsa:2627|GATA6; GATA binding protein 6; K17897 GATA-binding protein 6 (A)	--	[K]	Transcription	"GATA-type transcription activator, N-terminal;; GATA zinc finger"	Transcription factor GATA-6 GN=GATA6 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor GATA-6-like [Lipotes vexillifer]
ENSG00000141449(GREB1L)	--	1.491523922	144	0.808073978	112	1.127020581	143	1.162516541	169	1.138287938	160	0.792592534	132	0.952663461	0.198168937	normal	0.768601797	0.487611924	normal	0.963658999	-0.122420742	normal	0.677882882	0.186740676	normal	--	--	--	--	--	--	--	--	GREB1-like protein GN=GREB1L OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: growth regulation by estrogen in breast cancer-like isoform X2 [Equus caballus]
ENSG00000141452(C18orf8)	--	8.697384	326	9.117750005	342	10.131888	378	6.117279	230	7.26017387	271	5.284396646	198	0.426003346	-0.531073735	normal	0.844150723	-0.355360364	normal	0.000358029	-0.93591249	normal	0.006949827	-0.602784754	normal	--	--	--	--	--	[S]	Function unknown	Colon cancer-associated protein Mic1-like	Uncharacterized protein C18orf8 GN=C18orf8 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C18orf8 homolog isoform X1 [Mustela putorius furo]
ENSG00000141456(PELP1)	--	39.44644521	2775	41.15936298	3000	41.66365929	3031	37.7483752	2699	39.66870775	2646	31.81922755	2300	0.988435305	-0.070855276	normal	0.976689414	-0.202467235	normal	0.767284509	-0.406217997	normal	0.201340458	-0.22553338	normal	--	--	--	"K16913|0|pps:100990218|PELP1; proline, glutamate and leucine rich protein 1; K16913 proline-, glutamic acid- and leucine-rich protein 1 (A)"	--	--	--	NUC202 domain;; rRNA processing/ribosome biogenesis	"Proline-, glutamic acid- and leucine-rich protein 1 GN=PELP1 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: proline-, glutamic acid- and leucine-rich protein 1 [Loxodonta africana]"
ENSG00000141458(NPC1)	--	44.98926085	3279	46.754185	3582	50.21671467	3769	62.502102	4572	45.551413	3193	150.001717	10965	0.662844314	0.44855853	normal	0.981717467	-0.187195578	normal	0	1.53198311	up	0.510086284	0.798939144	normal	--	--	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K12385|0|hsa:4864|NPC1, NPC; Niemann-Pick disease, type C1; K12385 Niemann-Pick C1 protein (A)"	Lysosome (ko04142)	[I]	Lipid transport and metabolism	Patched family;; Sterol-sensing domain of SREBP cleavage-activation;; MMPL family	Niemann-Pick C1 protein (Precursor) GN=NPC1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: niemann-Pick C1 protein [Tupaia chinensis]
ENSG00000141469(SLC14A1)	--	0	0	0	0	0	0	0.080602132	1	0.082082048	3	0.033080812	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: urea transmembrane transporter activity (GO:0015204);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: urea transmembrane transport (GO:0071918);; 	"K08716|0|hsa:6563|SLC14A1, HUT11, HsT1341, JK, RACH1, RACH2, UT-B1, UT1, UTE; solute carrier family 14 (urea transporter), member 1 (Kidd blood group); K08716 solute carrier family 14 (urea transporter) (A)"	--	--	--	Urea transporter	Urea transporter 1 GN=SLC14A1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: urea transporter 1 [Elephantulus edwardii]
ENSG00000141480(ARRB2)	--	40.86334343	1183	34.1824633	1032	36.55616041	1141	34.75907382	939	32.50897586	980	29.99413461	909	0.811509763	-0.363553908	normal	0.975528862	-0.095871682	normal	0.85991697	-0.335738358	normal	0.133584396	-0.268130915	normal	--	--	--	"K04439|0|hsa:409|ARRB2, ARB2, ARR2, BARR2; arrestin, beta 2; K04439 beta-arrestin (A)"	MAPK signaling pathway (ko04010);; Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Phototransduction (ko04744);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	"Arrestin (or S-antigen), N-terminal domain;; Arrestin (or S-antigen), C-terminal domain"	Beta-arrestin-2 GN=ARRB2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: beta-arrestin-2 isoform X1 [Condylura cristata]
ENSG00000141485(SLC13A5)	--	0.050999854	3	0.05074466	3	0.149911876	8	0.03379456	1	0.063338483	3	0.218937057	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14445|0|ptr:455245|SLC13A5; solute carrier family 13 (sodium-dependent citrate transporter), member 5; K14445 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:sulfate symporter transmembrane region;; Citrate transporter	Solute carrier family 13 member 5 GN=SLC13A5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 13 member 5 [Tupaia chinensis]
ENSG00000141497(ZMYND15)	--	0.105165154	5	0.102235426	5	0.06037474	2	0.104667478	5	0	0	0.145881037	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	MYND finger	Zinc finger MYND domain-containing protein 15 GN=ZMYND15 OS=Homo sapiens (Human) PE=2 SV=2	B	Chromatin structure and dynamics	PREDICTED: zinc finger MYND domain-containing protein 15 isoform 1 [Trichechus manatus latirostris]
ENSG00000141499(WRAP53)	--	18.70593746	714	16.97343263	658	21.02206562	767	19.6548321	745	20.71229112	766	16.50903	626	0.975484842	0.030420005	normal	0.95294091	0.197409424	normal	0.893531242	-0.30069791	normal	0.9508736	-0.022768607	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Telomerase Cajal body protein 1 GN=WRAP53 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: telomerase Cajal body protein 1 [Ceratotherium simum simum]
ENSG00000141503(MINK1)	--	34.36267424	3730	33.0336265	3463	35.578529	3791	32.10085917	3514	26.819207	3020	29.170092	3273	0.988828028	-0.116844104	normal	0.975788567	-0.218797983	normal	0.976908429	-0.220161684	normal	0.328937134	-0.184876092	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04413|0|ecb:100061370|MINK1; misshapen-like kinase 1; K04413 misshapen/NIK-related kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; CNH domain;; Protein tyrosine kinase	Misshapen-like kinase 1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: misshapen-like kinase 1 isoform 1 [Ceratotherium simum simum]
ENSG00000141504(SAT2)	--	54.2479	700	59.78993	783	57.74726	755	47.1069	599	56.55022	705	64.00645	818	0.926999729	-0.2550253	normal	0.960128342	-0.172464366	normal	0.971778967	0.107126561	normal	0.707684786	-0.097017654	normal	[KR]	Transcription;; General function prediction only	"Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	"K00657|9.25128e-122|hsa:112483|SAT2, SSAT2; spermidine/spermine N1-acetyltransferase family member 2 (EC:2.3.1.57); K00657 diamine N-acetyltransferase [EC:2.3.1.57] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; FR47-like protein;; Acetyltransferase (GNAT) domain	Diamine acetyltransferase 2 GN=SAT2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: diamine acetyltransferase 2 [Galeopterus variegatus]
ENSG00000141505(ASGR1)	--	1.535202662	36	0.759846693	12	0.53997937	16	0.505958324	12	0.966333264	21	0.268540993	7	0.23994052	-1.499893159	normal	0.97262599	0.716933044	normal	--	--	--	--	--	--	--	--	--	K10063|2.24646e-174|pps:100987509|ASGR1; asialoglycoprotein receptor 1; K10063 asialoglycoprotein receptor 1 (A)	Thyroid hormone synthesis (ko04918)	[TV]	Signal transduction mechanisms;; Defense mechanisms	"Hepatic lectin, N-terminal domain;; Lectin C-type domain"	Asialoglycoprotein receptor 1 GN=ASGR1 OS=Homo sapiens (Human) PE=1 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: asialoglycoprotein receptor 1 [Balaenoptera acutorostrata scammoni]
ENSG00000141506(PIK3R5)	--	0.01075086	1	0.042839144	4	0.073407142	6	0	0	0.020983064	1	0.010643412	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: phosphatidylinositol 3-kinase complex, class IB (GO:0005944);; Molecular Function: 1-phosphatidylinositol-3-kinase regulator activity (GO:0046935);; "	"K02649|0|hsa:23533|PIK3R5, F730038I15Rik, FOAP-2, P101-PI3K, p101; phosphoinositide-3-kinase, regulatory subunit 5; K02649 phosphoinositide-3-kinase, regulatory subunit (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; Carbohydrate digestion and absorption (ko04973);; Bacterial invasion of epithelial cells (ko05100);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	--	--	Phosphoinositide 3-kinase gamma adapter protein p101 subunit	Phosphoinositide 3-kinase regulatory subunit 5 GN=PIK3R5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosphoinositide 3-kinase regulatory subunit 5 isoform 1 [Ceratotherium simum simum]
ENSG00000141510(TP53)	--	56.19536107	2581	61.98553764	2748	60.939183	2672	60.63540627	2775	60.64163276	2761	72.2392823	3317	0.988142711	0.073683062	normal	0.989245137	-0.014609653	normal	0.93923429	0.303513101	normal	0.552736121	0.125306458	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: transcription regulatory region DNA binding (GO:0044212);; Biological Process: protein tetramerization (GO:0051262);; 	K04451|0|ptr:455214|TP53; tumor protein p53; K04451 tumor protein p53 (A)	MAPK signaling pathway (ko04010);; Sphingolipid signaling pathway (ko04071);; Cell cycle (ko04110);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Wnt signaling pathway (ko04310);; Neurotrophin signaling pathway (ko04722);; Thyroid hormone signaling pathway (ko04919);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Basal cell carcinoma (ko05217);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230)	--	--	P53 DNA-binding domain;; P53 tetramerisation motif;; P53 transactivation motif	Cellular tumor antigen p53 GN=TP53 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	tumor protein p53 [Tupaia chinensis] 
ENSG00000141519(CCDC40)	--	4.320835259	257	2.608777021	229	3.6968342	304	2.3811295	185	2.37097683	212	2.206075577	229	0.594412259	-0.501523739	normal	0.95842539	-0.13180495	normal	0.763504203	-0.414630471	normal	0.208798623	-0.355781553	normal	--	--	--	--	--	--	--	BRE1 E3 ubiquitin ligase	Coiled-coil domain-containing protein 40 GN=CCDC40 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 40 [Equus caballus]
ENSG00000141522(ARHGDIA)	--	185.5959568	6658	166.2106449	6052	198.7527555	7301	199.6959082	7221	200.7865499	7195	157.6564313	5699	0.994108813	0.086258393	normal	0.98441898	0.228103813	normal	0.918128278	-0.365590789	normal	0.968906504	-0.014072367	normal	--	--	Molecular Function: Rho GDP-dissociation inhibitor activity (GO:0005094);; Cellular Component: cytoplasm (GO:0005737);; 	K12462|2.0328e-99|ptr:454971|ARHGDIA; Rho GDP dissociation inhibitor (GDI) alpha; K12462 Rho GDP-dissociation inhibitor (A)	Neurotrophin signaling pathway (ko04722);; Vasopressin-regulated water reabsorption (ko04962)	[T]	Signal transduction mechanisms	RHO protein GDP dissociation inhibitor	Rho GDP-dissociation inhibitor 1 GN=ARHGDIA OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: Rho GDP dissociation inhibitor (GDI) alpha, partial [Myotis lucifugus]"
ENSG00000141524(TMC6)	--	9.49580805	439	4.784406068	252	6.4694539	308	4.968615182	199	6.525671989	264	5.597718248	252	4.55E-07	-1.166057178	down	0.965340014	0.045421321	normal	0.903610292	-0.296187464	normal	0.256430339	-0.503049993	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 6 GN=TMC6 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane channel-like protein 6 [Ceratotherium simum simum]
ENSG00000141526(SLC16A3)	--	203.5317774	5102	164.763347	4392	174.7204064	4627	243.921355	6408	180.9346316	4627	162.1442975	4126	0.963394668	0.297898797	normal	0.992188225	0.053754453	normal	0.986397443	-0.17356461	normal	0.853525777	0.079880638	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08180|0|hsa:9123|SLC16A3, MCT_3, MCT_4, MCT-3, MCT-4, MCT3, MCT4; solute carrier family 16 (monocarboxylate transporter), member 3; K08180 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 3 (A)"	Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 4 GN=SLC16A3 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 4 [Leptonychotes weddellii]
ENSG00000141527(CARD14)	--	0.276114173	23	0.344795355	27	0.443558688	33	0.4628189	39	0.695661114	55	0.631500104	51	0.930636024	0.695010097	normal	0.554243163	0.966409165	normal	0.920386765	0.597554543	normal	0.164888645	0.785033634	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	--	--	--	--	Caspase recruitment domain;; Guanylate kinase	Caspase recruitment domain-containing protein 14 GN=CARD14 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: caspase recruitment domain-containing protein 14 [Galeopterus variegatus]
ENSG00000141540(TTYH2)	--	1.771339055	120	0.946243066	64	1.250391486	85	1.71811016	115	1.79526487	119	1.287210475	84	0.967374451	-0.091041906	normal	0.153365587	0.858297991	normal	0.97245112	-0.024918971	normal	0.688756215	0.219425133	normal	--	--	--	--	--	[R]	General function prediction only	Tweety	Protein tweety homolog 2 GN=TTYH2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein tweety homolog 2 [Felis catus]
ENSG00000141542(RAB40B)	--	3.837176241	164	3.420818561	148	2.650128684	146	4.368760717	176	5.551083643	208	5.012057694	205	0.965673792	0.070410548	normal	0.742218779	0.465529929	normal	0.722709186	0.477173907	normal	0.315291606	0.342135846	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K07928|0|ptr:454998|RAB40B; RAB40B, member RAS oncogene family; K07928 Ras-related protein Rab-40 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; SOCS box;; ADP-ribosylation factor family	Ras-related protein Rab-40B GN=RAB40B OS=Homo sapiens (Human) PE=2 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-40B isoform 1 [Odobenus rosmarus divergens]
ENSG00000141543(EIF4A3)	--	64.99563	2230	64.4276433	2298	68.6874261	2459	69.17280098	2449	76.01404	2593	60.5119	2127	0.985429816	0.104248248	normal	0.981677944	0.152722194	normal	0.969842699	-0.217399251	normal	0.960928484	0.015709659	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K13025|0|ssc:100101926|EIF4A3, DDX48, eIF4A-III; eukaryotic translation initiation factor 4A3 (EC:3.6.4.13); K13025 ATP-dependent RNA helicase [EC:3.6.4.13] (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040)	[J]	"Translation, ribosomal structure and biogenesis"	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	"Eukaryotic initiation factor 4A-III, N-terminally processed GN=EIF4A3 OS=Homo sapiens (Human) PE=1 SV=4"	J	"Translation, ribosomal structure and biogenesis"	eukaryotic initiation factor 4A-III [Bos taurus] 
ENSG00000141551(CSNK1D)	--	76.5947	4535	68.637873	4298	70.614772	4228	71.242964	4396	83.27717	4881	73.50772	4578	0.991920471	-0.075717371	normal	0.98770102	0.162031185	normal	0.990797379	0.106414057	normal	0.800513651	0.064053588	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08959|0|ngi:103729985|Csnk1d; casein kinase 1, delta; K08959 casein kinase 1, delta [EC:2.7.11.1] (A)"	Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Gap junction (ko04540);; Circadian rhythm (ko04710)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Casein kinase I isoform delta GN=CSNK1D OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: casein kinase I isoform delta isoform X1 [Erinaceus europaeus]
ENSG00000141552(ANAPC11)	--	179.8402561	1472	176.1492656	1535	178.826927	1564	191.2594744	1607	190.4297713	1528	195.3158915	1609	0.981313353	0.095664413	normal	0.983643669	-0.027993028	normal	0.984336869	0.032601291	normal	0.9074175	0.032450691	normal	[OD]	"Posttranslational modification, protein turnover, chaperones;; Cell cycle control, cell division, chromosome partitioning"	--	"K03358|1.27894e-115|hsa:51529|ANAPC11, APC11, Apc11p; anaphase promoting complex subunit 11; K03358 anaphase-promoting complex subunit 11 (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	Anaphase-promoting complex subunit 11 RING-H2 finger;; RING-H2 zinc finger;; Anaphase-promoting complex subunit 11 RING-H2 finger;; RING-H2 zinc finger;; Ring finger domain	Anaphase-promoting complex subunit 11 GN=ANAPC11 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: uncharacterized protein LOC101361853 [Trichechus manatus latirostris]
ENSG00000141556(TBCD)	--	30.57524424	2372	29.10583328	2327	34.67185954	2772	30.39692042	2504	33.19525418	2629	27.59788917	1897	0.988089947	0.047268489	normal	0.981649399	0.154521853	normal	0.151448532	-0.55513066	normal	0.707323993	-0.109354441	normal	[OZ]	"Posttranslational modification, protein turnover, chaperones;; Cytoskeleton"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin folding cofactor D C terminal;; HEAT-like repeat	Tubulin-specific chaperone D GN=TBCD OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin-specific chaperone D [Oryctolagus cuniculus]
ENSG00000141560(FN3KRP)	--	34.74146296	1129	35.53762816	1186	36.77467026	1234	37.33605851	1146	34.5860487	1109	32.82440152	1074	0.980996224	-0.0092582	normal	0.975249935	-0.118115411	normal	0.958683784	-0.20836589	normal	0.613385829	-0.113601373	normal	[G]	Carbohydrate transport and metabolism	--	"K15523|0|hsa:79672|FN3KRP, FN3KL; fructosamine 3 kinase related protein; K15523 protein-ribulosamine 3-kinase [EC:2.7.1.172] (A)"	--	[R]	General function prediction only	Fructosamine kinase;; Phosphotransferase enzyme family	Ketosamine-3-kinase GN=FN3KRP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ketosamine-3-kinase isoform 1 [Odobenus rosmarus divergens]
ENSG00000141562(NARF)	--	27.64958656	1004	28.86498404	1053	27.21481011	941	30.01086688	1135	23.36189778	795	27.5523556	975	0.971051475	0.145890702	normal	0.647580589	-0.426198236	normal	0.978425982	0.042848401	normal	0.82927863	-0.067452412	normal	[R]	General function prediction only	--	--	--	[Y]	Nuclear structure	"Iron only hydrogenase large subunit, C-terminal domain;; Iron hydrogenase small subunit"	Nuclear prelamin A recognition factor GN=NARF OS=Homo sapiens (Human) PE=1 SV=1	Y	Nuclear structure	PREDICTED: nuclear prelamin A recognition factor isoform X1 [Mustela putorius furo] 
ENSG00000141564(RPTOR)	--	26.91152954	2114	28.766497	2278	25.25762934	2238	24.345575	1963	26.22540099	2180	22.99076479	2103	0.981236193	-0.137643617	normal	0.985675963	-0.08480861	normal	0.985042177	-0.097984312	normal	0.623093513	-0.107001851	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K07204|0|pps:100976440|RPTOR; regulatory associated protein of MTOR, complex 1; K07204 regulatory associated protein of mTOR (A)"	mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; MicroRNAs in cancer (ko05206)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Raptor N-terminal CASPase like domain;; HEAT repeat;; HEAT repeats;; WD domain, G-beta repeat;; non-SMC mitotic condensation complex subunit 1;; HEAT-like repeat"	Regulatory-associated protein of mTOR GN=RPTOR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: regulatory-associated protein of mTOR isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000141568(FOXK2)	--	31.09014942	2804	32.49265004	2875	31.46810743	2874	31.25840039	2874	32.83858817	2884	30.68054635	2808	0.989819433	0.004738884	normal	0.989576442	-0.016908469	normal	0.989457047	-0.041786323	normal	0.952709638	-0.019040136	normal	--	--	--	K09404|1.18441e-30|pps:100975385|forkhead box protein K2; K09404 forkhead box protein K (A)	--	[K]	Transcription	Putative binding domain	Forkhead box protein K2 GN=FOXK2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: forkhead box protein K2 [Equus przewalskii]
ENSG00000141569(TRIM65)	--	21.27108002	1313	17.94370707	1106	20.24963627	1249	22.70075118	1382	22.76538043	1333	19.74505155	1162	0.982295709	0.04300938	normal	0.944847903	0.247590094	normal	0.976942391	-0.112313827	normal	0.822074488	0.05835913	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K12031|0|ptr:737934|TRIM65; tripartite motif containing 65; K12031 tripartite motif-containing protein 65 (A)	--	--	--	"Zinc finger, C3HC4 type (RING finger);; SPRY domain;; zinc finger of C3HC4-type, RING;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger"	Tripartite motif-containing protein 65 GN=TRIM65 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 65 [Ceratotherium simum simum]
ENSG00000141570(CBX8)	--	11.29343285	480	13.47283063	439	12.27457001	455	10.9306081	345	9.512715107	350	12.98601337	433	0.411081306	-0.505352591	normal	0.843717358	-0.346950828	normal	0.967795701	-0.079519997	normal	0.182450863	-0.305134952	normal	--	--	--	"K11455|0|hsa:57332|CBX8, PC3, RC1; chromobox homolog 8; K11455 chromobox protein 8 (A)"	--	[B]	Chromatin structure and dynamics	Chromo (CHRromatin Organisation MOdifier) domain	Chromobox protein homolog 8 GN=CBX8 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: chromobox protein homolog 8 [Galeopterus variegatus]
ENSG00000141574(SECTM1)	--	0.207743144	8	0.29268701	6	0.29811901	8	2.042218065	79	4.335420615	107	1.965403981	52	2.00E-10	3.050061314	up	0	3.833342845	up	2.23E-05	2.484490799	up	7.22E-07	3.413723121	up	--	--	--	--	--	--	--	Alphaherpesvirus glycoprotein E	Secreted and transmembrane protein 1 (Precursor) GN=SECTM1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: secreted and transmembrane protein 1 [Leptonychotes weddellii]
ENSG00000141576(RNF157)	--	6.243450716	564	5.454853816	452	5.326367	480	6.457487293	584	7.995399528	726	6.688290119	519	0.973007921	0.019389037	normal	0.032743428	0.660461408	normal	0.966692682	0.10409323	normal	0.332407304	0.26852366	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 157 GN=RNF157 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 157 isoform X1 [Tupaia chinensis]
ENSG00000141577(CEP131)	--	7.524148009	466	7.289116078	400	7.240902558	529	7.259732029	435	7.394637297	486	4.687793193	290	0.962334278	-0.129704062	normal	0.921562209	0.258641466	normal	0.000454637	-0.872087586	normal	0.565217571	-0.225797121	normal	--	--	--	"K16540|0|pps:100973155|CEP131, AZI1; centrosomal protein 131kDa; K16540 5-azacytidine-induced protein 1 (A)"	--	--	--	--	Centrosomal protein of 131 kDa GN=CEP131 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: 5-azacytidine-induced protein 1 isoform X3 [Equus caballus]
ENSG00000141579(ZNF750)	--	0	0	0.139778	11	0.1895515	12	0.06311	5	0.0830515	5	0.0983743	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-finger	Zinc finger protein 750 GN=ZNF750 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 750 [Galeopterus variegatus]
ENSG00000141580(WDR45B)	--	46.77643	2236	42.68009	2050	43.13486	2063	43.65353	2086	48.89229	2335	42.69081	2044	0.982590779	-0.130920126	normal	0.978581686	0.166257102	normal	0.987010115	-0.021624142	normal	0.989156787	0.004890027	normal	[R]	General function prediction only	--	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat domain phosphoinositide-interacting protein 3 GN=WDR45B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: WD repeat domain phosphoinositide-interacting protein 3 [Chrysochloris asiatica]
ENSG00000141582(CBX4)	--	28.95685116	1573	24.22363609	1319	24.69011402	1385	24.16173201	1307	21.92355936	1190	29.19020572	1594	0.915987073	-0.297772158	normal	0.969312569	-0.169704588	normal	0.967395851	0.194276326	normal	0.772951985	-0.084821523	normal	--	--	--	K11452|0|ptr:744720|CBX4; chromobox homolog 4; K11452 chromobox protein 4 (A)	--	[B]	Chromatin structure and dynamics	Chromo (CHRromatin Organisation MOdifier) domain	E3 SUMO-protein ligase CBX4 GN=CBX4 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: E3 SUMO-protein ligase CBX4 [Odobenus rosmarus divergens]
ENSG00000141622(RNF165)	--	0.288924824	18	0.111013966	6	0.124317089	7	0.332972549	18	0.633574546	26	0.196913593	19	--	--	--	0.265693433	1.854071992	normal	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K17821|0|nle:100579724|RNF165; ring finger protein 165; K17821 RING finger protein 165 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	RING finger protein 165 GN=RNF165 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 165 isoform X1 [Pteropus alecto]
ENSG00000141627(DYM)	--	15.29388343	659	15.86362794	580	16.37197016	595	18.01591113	689	16.45665135	756	17.84069382	769	0.974488734	0.033317286	normal	0.815232801	0.360082303	normal	0.809157327	0.360993312	normal	0.218241502	0.250781805	normal	--	--	--	--	--	[R]	General function prediction only	Dyggve-Melchior-Clausen syndrome protein;; High-temperature-induced dauer-formation protein	Dymeclin GN=DYM OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: dymeclin [Capra hircus]
ENSG00000141639(MAPK4)	--	0	0	0	0	0	0	0.017131643	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06855|0|ptr:468536|MAPK4; mitogen-activated protein kinase 4; K06855 mitogen-activated protein kinase 4/6 [EC:2.7.11.24] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase 4 GN=MAPK4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 4 [Odobenus rosmarus divergens]
ENSG00000141642(ELAC1)	--	3.218449927	71	3.352246925	72	3.416491478	76	3.346463	90	2.998588792	92	3.938499283	106	0.951027829	0.30539312	normal	0.943311539	0.326137612	normal	0.877164162	0.463852371	normal	0.439378065	0.374538889	normal	[R]	General function prediction only	Biological Process: tRNA processing (GO:0008033);; 	"K00784|0|hsa:55520|ELAC1, D29; elaC ribonuclease Z 1 (EC:3.1.26.11); K00784 ribonuclease Z [EC:3.1.26.11] (A)"	RNA transport (ko03013)	[R]	General function prediction only	Beta-lactamase superfamily domain;; Metallo-beta-lactamase superfamily;; tRNase Z endonuclease	Zinc phosphodiesterase ELAC protein 1 GN=ELAC1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc phosphodiesterase ELAC protein 1 isoform X1 [Sus scrofa]
ENSG00000141644(MBD1)	--	12.08024165	687	12.97249382	770	10.71341181	714	12.31188038	812	13.01871023	842	14.08571302	924	0.94992222	0.209905198	normal	0.97148916	0.107333599	normal	0.806832285	0.362999695	normal	0.254723633	0.227031168	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; 	K11589|0|ptr:455418|MBD1; methyl-CpG binding domain protein 1; K11589 methyl-CpG-binding domain protein 1 (A)	--	--	--	CXXC zinc finger domain;; Methyl-CpG binding domain	Methyl-CpG-binding domain protein 1 GN=MBD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: methyl-CpG-binding domain protein 1 isoform X2 [Sus scrofa] 
ENSG00000141646(SMAD4)	--	13.27805775	805	16.02757757	1016	15.03226697	936	14.25102121	976	17.90952605	971	17.44541179	965	0.937454193	0.246632087	normal	0.976074638	-0.086651809	normal	0.978549874	0.035672207	normal	0.83307538	0.057693617	normal	--	--	"Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04501|0|ptr:468537|SMAD4; SMAD family member 4; K04501 mothers against decapentaplegic homolog 4 (A)	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Wnt signaling pathway (ko04310);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Chronic myeloid leukemia (ko05220)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain	Mothers against decapentaplegic homolog 4 GN=SMAD4 OS=Homo sapiens (Human) PE=1 SV=1	KT	Transcription;; Signal transduction mechanisms	PREDICTED: mothers against decapentaplegic homolog 4 [Chrysochloris asiatica]
ENSG00000141655(TNFRSF11A)	--	3.293030375	244	3.330089	243	4.182579605	225	3.527520384	266	3.43742701	233	2.023404142	156	0.963497841	0.093150973	normal	0.963215571	-0.081534663	normal	0.559572999	-0.532348894	normal	0.718634892	-0.143195557	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05147|0|ggo:101133276|TNFRSF11A; tumor necrosis factor receptor superfamily member 11A isoform 1; K05147 tumor necrosis factor receptor superfamily member 11A (A)	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Osteoclast differentiation (ko04380);; Prolactin signaling pathway (ko04917);; Rheumatoid arthritis (ko05323)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 11A (Precursor) GN=TNFRSF11A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 11A [Oryctolagus cuniculus]
ENSG00000141664(ZCCHC2)	--	4.386976367	417	4.961172	441	5.2038628	442	4.906378671	448	3.87483475	352	4.957108492	453	0.967954693	0.072361838	normal	0.84572442	-0.345301269	normal	0.970450885	0.02708171	normal	0.82445739	-0.074348511	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Zinc knuckle	Zinc finger CCHC domain-containing protein 2 GN=ZCCHC2 OS=Homo sapiens (Human) PE=1 SV=6	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: zinc finger CCHC domain-containing protein 2 [Galeopterus variegatus]
ENSG00000141665(FBXO15)	--	1.909674446	50	2.027540439	37	1.056921896	26	0.78587508	20	0.723764812	19	0.928187175	25	0.17049198	-1.288084763	normal	0.83331322	-0.929046543	normal	0.98634879	-0.06124203	normal	0.16872218	-0.841488004	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10298|0|hsa:201456|FBXO15, FBX15; F-box protein 15; K10298 F-box protein 15 (A)"	--	--	--	F-box-like;; F-box domain	F-box only protein 15 GN=FBXO15 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: F-box only protein 15 isoform X2 [Equus przewalskii]
ENSG00000141668(CBLN2)	--	0	0	0.025796756	1	0	0	0.192228233	8	0.101468297	3	0.23862008	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain	Cerebellin-2 (Precursor) GN=CBLN2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: cerebellin-2-like [Tursiops truncatus] 
ENSG00000141682(PMAIP1)	--	14.45190288	366	17.20473644	437	16.9232697	418	19.29131104	495	15.78907618	401	18.87080072	481	0.733304387	0.403292146	normal	0.958566455	-0.144933804	normal	0.949032407	0.19358911	normal	0.582785175	0.152129184	normal	--	--	Biological Process: release of cytochrome c from mitochondria (GO:0001836);; Biological Process: apoptotic process (GO:0006915);; Biological Process: activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919);; Biological Process: cellular response to DNA damage stimulus (GO:0006974);; 	K10131|3.604e-15|cjc:100404690|PMAIP1; phorbol-12-myristate-13-acetate-induced protein 1; K10131 phorbol-12-myristate-13-acetate-induced protein 1 (A)	p53 signaling pathway (ko04115);; Viral carcinogenesis (ko05203)	--	--	--	Phorbol-12-myristate-13-acetate-induced protein 1 GN=PMAIP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: phorbol-12-myristate-13-acetate-induced protein 1 [Leptonychotes weddellii]
ENSG00000141696(P3H4)	--	28.0326	1367	27.63469	1074	21.1595586	1103	24.6697219	1236	24.882176	1208	23.35304	1100	0.968941526	-0.175958655	normal	0.971398267	0.148003319	normal	0.980668382	-0.012203954	normal	0.948801382	-0.02164546	normal	--	--	--	--	--	[S]	Function unknown	--	Synaptonemal complex protein SC65 GN=LEPREL4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: synaptonemal complex protein SC65 [Lipotes vexillifer]
ENSG00000141698(NT5C3B)	--	58.03445176	1444	53.58464261	1366	59.18981417	1467	57.72141497	1454	54.218773	1343	57.33950225	1442	0.9835478	-0.020853625	normal	0.981876585	-0.045873517	normal	0.983418621	-0.033054779	normal	0.902883774	-0.034033431	normal	--	--	Molecular Function: magnesium ion binding (GO:0000287);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: 5'-nucleotidase activity (GO:0008253);; 	"K01081|0|ptr:743177|NT5C3B, NT5C3L; 5'-nucleotidase, cytosolic IIIB; K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	[S]	Function unknown	Pyrimidine 5'-nucleotidase (UMPH-1)	7-methylguanosine phosphate-specific 5'-nucleotidase GN=NT5C3B OS=Homo sapiens (Human) PE=1 SV=4	F	Nucleotide transport and metabolism	PREDICTED: 7-methylguanosine phosphate-specific 5'-nucleotidase isoform 1 [Canis lupus familiaris]
ENSG00000141699(FAM134C)	--	18.73304022	1183	19.8058843	1264	18.74847037	1188	23.13913718	1455	21.77103528	1357	23.34392742	1470	0.935537422	0.267423199	normal	0.979938971	0.080904269	normal	0.912687472	0.298647503	normal	0.238760718	0.215073724	normal	--	--	--	--	--	--	--	--	Protein FAM134C GN=FAM134C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM134C [Ovis aries]
ENSG00000141736(ERBB2)	--	20.29527795	1710	24.88806636	1842	21.34828358	1899	27.72285963	2283	29.70969251	2401	26.9394711	2393	0.79723885	0.385801381	normal	0.860781171	0.360675751	normal	0.90587594	0.325057961	normal	0.022680116	0.355694095	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);; Cellular Component: membrane (GO:0016020);; 	K05083|0|pps:100977227|ERBB2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; K05083 receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1] (A)	ErbB signaling pathway (ko04012);; Calcium signaling pathway (ko04020);; HIF-1 signaling pathway (ko04066);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Bladder cancer (ko05219);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Receptor L domain;; Growth factor receptor domain IV;; Protein kinase domain;; Furin-like cysteine rich region	Receptor tyrosine-protein kinase erbB-2 (Precursor) GN=ERBB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: receptor tyrosine-protein kinase erbB-2 [Equus caballus]
ENSG00000141738(GRB7)	--	2.6866111	99	2.713034363	103	3.62816685	134	4.412711475	155	5.3252741	163	3.217712182	122	0.538205149	0.608334478	normal	0.445372991	0.633349706	normal	0.962735496	-0.141963515	normal	0.346304322	0.367773134	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	BPS (Between PH and SH2);; SH2 domain;; Ras association (RalGDS/AF-6) domain;; PH domain	Growth factor receptor-bound protein 7 GN=GRB7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: growth factor receptor-bound protein 7 isoform X1 [Tupaia chinensis] 
ENSG00000141741(MIEN1)	--	54.14762	863	49.52725	820	57.69289	950	40.37462	660	42.86972	681	40.30965	652	0.664670597	-0.416875189	normal	0.906627085	-0.288810232	normal	0.173110902	-0.550283184	normal	0.013034092	-0.422736907	normal	--	--	--	"K07401|9.05044e-49|ptr:746327|MIEN1, C17H17orf37; migration and invasion enhancer 1; K07401 selenoprotein W-related protein (A)"	--	--	--	Rdx family	Migration and invasion enhancer 1 (Precursor) GN=MIEN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: migration and invasion enhancer 1 isoform X1 [Mustela putorius furo]
ENSG00000141750(STAC2)	--	0.177308	13	0.121123	9	0.132163	9	0.0410728	3	0.265921	19	0.108037	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	SH3 and cysteine-rich domain-containing protein 2 GN=STAC2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: SH3 and cysteine-rich domain-containing protein 2 [Orycteropus afer afer]
ENSG00000141753(IGFBP4)	--	1952.39	77315	1407.15	57423	1660.89	68062	1416.97	56874	1562.2	61423	1509.78	60125	0.91523288	-0.473800303	normal	0.999012119	0.075721787	normal	0.998337422	-0.187171571	normal	0.435466538	-0.205677121	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Thyroglobulin type-1 repeat;; Insulin-like growth factor binding protein	Insulin-like growth factor-binding protein 4 (Precursor) GN=IGFBP4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: insulin-like growth factor-binding protein 4, partial [Vicugna pacos]"
ENSG00000141756(FKBP10)	--	59.86486824	2916	51.02981579	2374	46.52909538	2341	50.25333178	2425	61.56859662	2765	42.09819653	2169	0.939746762	-0.29666653	normal	0.975899299	0.198415781	normal	0.984113837	-0.118306903	normal	0.804561531	-0.073940053	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K09575|0|hsa:60681|FKBP10, FKBP65, OI11, OI6, PPIASE, hFKBP65; FK506 binding protein 10, 65 kDa (EC:5.2.1.8); K09575 FK506-binding protein 9/10 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase;; EF hand;; EF hand;; EF-hand domain pair	Peptidyl-prolyl cis-trans isomerase FKBP10 (Precursor) GN=FKBP10 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP10 [Physeter catodon]
ENSG00000141759(TXNL4A)	--	59.40902	905	52.43489001	907	60.6443473	1020	65.14204045	1083	53.84623301	999	59.9741	964	0.948469962	0.227857303	normal	0.972678428	0.117768421	normal	0.976353616	-0.089618844	normal	0.735795444	0.083755624	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Cellular Component: spliceosomal complex (GO:0005681);; Biological Process: cell redox homeostasis (GO:0045454);; "	"K12859|5.46476e-103|cjc:100403127|TXNL4A; thioredoxin-like 4A; K12859 U5 snRNP protein, DIM1 family (A)"	Spliceosome (ko03040)	[AD]	"RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	Mitosis protein DIM1;; Thioredoxin	Thioredoxin-like protein 4A GN=TXNL4A OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: thioredoxin-like 4A isoform X1 [Equus caballus]
ENSG00000141837(CACNA1A)	--	0.132717791	12	0.279760237	24	0.14178411	7	0.013361231	2	0.108784852	3	0.079985495	9	--	--	--	0.036489226	-2.516466025	normal	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04344|0|bta:282648|CACNA1A, CAV2.1; calcium channel, voltage-dependent, P/Q type, alpha 1A subunit; K04344 voltage-dependent calcium channel P/Q type alpha-1A (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; Synaptic vesicle cycle (ko04721);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Taste transduction (ko04742);; Type II diabetes mellitus (ko04930);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Voltage gated calcium channel IQ domain;; Polycystin cation channel	Voltage-dependent P/Q-type calcium channel subunit alpha-1A GN=CACNA1A OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent P/Q-type calcium channel subunit alpha-1A isoform 1 [Orcinus orca]
ENSG00000141854(MISP3)	--	3.444951393	76	2.802073234	62	4.456373522	102	3.28549947	73	2.190784264	47	1.813246146	41	0.972988738	-0.087137568	normal	0.946530594	-0.409523027	normal	0.002394498	-1.291933623	down	0.208246841	-0.598299073	normal	--	--	--	--	--	--	--	A-kinase anchor protein 2 C-terminus	Uncharacterized protein LOC113230 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: uncharacterized protein LOC113230-like isoform X1 [Physeter catodon]
ENSG00000141858(SAMD1)	--	19.5798541	719	19.49944486	739	18.91243221	727	19.75355056	731	17.27136713	633	13.85612	518	0.975779007	-0.006937925	normal	0.934008854	-0.244254717	normal	0.382310532	-0.496066201	normal	0.250809028	-0.237592973	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SAM domain (Sterile alpha motif);; Sterile alpha motif (SAM)/Pointed domain	Atherin GN=SAMD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: atherin, partial [Galeopterus variegatus]"
ENSG00000141867(BRD4)	--	14.2083234	1875	16.87048502	2061	15.45431484	1973	14.510355	1711	16.75328466	1925	13.96863354	1858	0.976388009	-0.162743427	normal	0.98227531	-0.11982162	normal	0.983898606	-0.09485696	normal	0.546262873	-0.125973513	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	K11722|0|pps:100973498|BRD4; bromodomain containing 4; K11722 bromodomain-containing protein 4 (A)	--	[K]	Transcription	Bromodomain	Bromodomain-containing protein 4 GN=BRD4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: bromodomain-containing protein 4 isoform 1 [Canis lupus familiaris]
ENSG00000141873(SLC39A3)	--	28.0853621	807	29.83449551	834	25.80127257	776	20.70211677	530	24.37391638	632	24.19782824	603	0.039866592	-0.635902567	normal	0.666345042	-0.420670035	normal	0.788251039	-0.371366818	normal	0.005407408	-0.474405264	normal	--	--	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14709|0|hsa:29985|SLC39A3, ZIP-3, ZIP3; solute carrier family 39 (zinc transporter), member 3; K14709 solute carrier family 39 (zinc transporter), member 1/2/3 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP3 GN=SLC39A3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP3 [Canis lupus familiaris]
ENSG00000141905(NFIC)	--	17.6757774	2458	21.81638358	2692	20.51707061	2624	17.70121954	2267	19.8180838	2355	15.70099181	2159	0.982072863	-0.147436786	normal	0.972393502	-0.21424911	normal	0.940703661	-0.289511664	normal	0.218105957	-0.218443477	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09170|0|hsa:4782|NFIC, CTF, CTF5, NF-I, NFI; nuclear factor I/C (CCAAT-binding transcription factor); K09170 nuclear factor I/C (A)"	--	[K]	Transcription	CTF/NF-I family transcription modulation region;; Nuclear factor I protein pre-N-terminus;; MH1 domain	Nuclear factor 1 C-type GN=NFIC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear factor 1 C-type isoform 1 [Trichechus manatus latirostris]
ENSG00000141933(TPGS1)	--	17.2021	230	15.1739	215	14.517	210	15.1049	209	16.3527	221	19.0581	259	0.95434966	-0.167786749	normal	0.96571543	0.018157184	normal	0.911403001	0.292372208	normal	0.911558094	0.052373368	normal	--	--	--	"K16581|0|hsa:91978|TPGS1, C19orf20, GTRGEO22, PGs1; tubulin polyglutamylase complex subunit 1; K16581 tubulin polyglutamylase complex subunit 1 (A)"	--	--	--	--	Tubulin polyglutamylase complex subunit 1 GN=TPGS1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	hypothetical protein PANDA_012705 [Ailuropoda melanoleuca]
ENSG00000141934(PLPP2)	--	57.820164	1170	65.02972331	1355	57.43558117	1220	61.322671	1222	72.941577	1453	78.18168397	1580	0.98123836	0.03186255	normal	0.980865502	0.079229892	normal	0.823253857	0.364354043	normal	0.449158169	0.163706088	normal	[I]	Lipid transport and metabolism	--	"K01080|0|hsa:8612|PPAP2C, LPP2, PAP-2c, PAP2-g; phosphatidic acid phosphatase type 2C (EC:3.1.3.4); K01080 phosphatidate phosphatase [EC:3.1.3.4] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Sphingolipid metabolism (ko00600);; Fc gamma R-mediated phagocytosis (ko04666);; Fat digestion and absorption (ko04975);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	PAP2 superfamily	Lipid phosphate phosphohydrolase 2 GN=PPAP2C OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	hypothetical protein PANDA_012698 [Ailuropoda melanoleuca]
ENSG00000141956(PRDM15)	--	1.567887715	226	2.074940623	299	1.916784239	277	1.611564724	229	1.776900058	244	1.742982456	252	0.966947223	-0.011728231	normal	0.891529475	-0.312935404	normal	0.957755057	-0.143929504	normal	0.625080584	-0.166468076	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	PR domain zinc finger protein 15 GN=PRDM15 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	hypothetical protein PANDA_011487 [Ailuropoda melanoleuca]
ENSG00000141959(PFKL)	--	42.8227	2493	35.5575	2122	39.6381	2376	36.9562	2162	32.3683	1875	34.9188	2042	0.964721424	-0.236192142	normal	0.971366009	-0.199809014	normal	0.966556358	-0.226687616	normal	0.206141391	-0.223000085	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: 6-phosphofructokinase activity (GO:0003872);; Biological Process: glycolytic process (GO:0006096);; 	"K00850|0|ptr:458602|PFKL; phosphofructokinase, liver; K00850 6-phosphofructokinase 1 [EC:2.7.1.11] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; RNA degradation (ko03018);; AMPK signaling pathway (ko04152);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Phosphofructokinase	"ATP-dependent 6-phosphofructokinase, liver type {ECO:0000255|HAMAP-Rule:MF_03184} GN=PFKL OS=Homo sapiens (Human) PE=1 SV=6"	G	Carbohydrate transport and metabolism	"PREDICTED: 6-phosphofructokinase, liver type [Galeopterus variegatus]"
ENSG00000141965(FEM1A)	--	2.65889	530	2.58735	522	2.52009	508	2.91515	580	2.66589	529	2.82227	565	0.968219782	0.098954013	normal	0.971574914	-0.002202304	normal	0.961868134	0.144722238	normal	0.788665466	0.08038927	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Protein fem-1 homolog A GN=FEM1A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein fem-1 homolog A [Pteropus alecto] 
ENSG00000141968(VAV1)	--	3.160051029	186	1.721877466	104	2.708064964	163	3.885874169	232	4.098484867	240	3.200364253	190	0.918629924	0.285872127	normal	3.65E-05	1.173479633	up	0.948075706	0.211021019	normal	0.080208059	0.525946694	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Biological Process: intracellular signal transduction (GO:0035556);; 	K05730|0|mcf:101867234|uncharacterized LOC101867234; K05730 guanine nucleotide exchange factor VAV (A)	cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	RhoGEF domain;; SH3 domain;; Variant SH3 domain;; CAMSAP CH domain;; Variant SH3 domain;; SH2 domain;; Calponin homology (CH) domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; PH domain;; CDC24 Calponin	Proto-oncogene vav GN=VAV1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: proto-oncogene vav isoform 1 [Odobenus rosmarus divergens]
ENSG00000141971(MVB12A)	--	18.76741529	406	15.72076847	343	13.75487919	329	14.28517088	345	18.08812778	397	14.31962304	314	0.918491955	-0.264627768	normal	0.948301408	0.188729891	normal	0.965738114	-0.075260318	normal	0.895946735	-0.051295374	normal	--	--	Cellular Component: ESCRT I complex (GO:0000813);; 	"K12186|0|hsa:93343|MVB12A, CFBP, FAM125A; multivesicular body subunit 12A; K12186 ESCRT-I complex subunit MVB12 (A)"	Endocytosis (ko04144)	[S]	Function unknown	Protein of unknown function (DUF2464)	Multivesicular body subunit 12A GN=MVB12A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: multivesicular body subunit 12A isoform X1 [Galeopterus variegatus]
ENSG00000141985(SH3GL1)	--	19.21856214	1011	19.55492831	1038	19.50126828	1042	23.93694306	1240	24.34565284	1271	20.3875403	1075	0.933630102	0.263362973	normal	0.930911853	0.270374534	normal	0.979780765	0.036637588	normal	0.319585114	0.192767595	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	K11247|0|ggo:101137224|SH3GL1; endophilin-A2 isoform 1; K11247 endophilin-A (A)	Endocytosis (ko04144)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	BAR domain;; SH3 domain;; Variant SH3 domain;; Bin/amphiphysin/Rvs domain for vesicular trafficking;; Variant SH3 domain	Endophilin-A2 GN=SH3GL1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endophilin-A2 isoform X1 [Condylura cristata]
ENSG00000141994(DUS3L)	--	10.4474855	466	10.75661167	528	9.311610651	440	8.982424121	408	10.13088969	453	9.549095864	438	0.939106816	-0.221810737	normal	0.930963892	-0.24170518	normal	0.970504137	-0.014813067	normal	0.540073449	-0.16382261	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: tRNA processing (GO:0008033);; Molecular Function: tRNA dihydrouridine synthase activity (GO:0017150);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	K05544|0|pps:100980187|DUS3L; dihydrouridine synthase 3-like (S. cerevisiae); K05544 tRNA-dihydrouridine synthase 3 [EC:1.3.1.89] (A)	--	[R]	General function prediction only	Dihydrouridine synthase (Dus);; Zinc finger C-x8-C-x5-C-x3-H type (and similar)	tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like GN=DUS3L OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like isoform 1 [Orcinus orca]
ENSG00000142002(DPP9)	--	27.60083488	2179	34.91878559	2399	33.33500728	2683	34.11227267	2720	33.7116596	2566	36.08433207	2686	0.941782136	0.28892555	normal	0.98709013	0.075615362	normal	0.989376257	-0.006675431	normal	0.59655146	0.113796407	normal	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Molecular Function: hydrolase activity (GO:0016787);; 	"K08656|0|hsa:91039|DPP9, DP9, DPLP9, DPRP-2, DPRP2; dipeptidyl-peptidase 9 (EC:3.4.14.5); K08656 dipeptidyl-peptidase 9 [EC:3.4.14.5] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Dipeptidyl peptidase IV (DPP IV) N-terminal region;; Prolyl oligopeptidase family;; X-Pro dipeptidyl-peptidase (S15 family)	Dipeptidyl peptidase 9 GN=DPP9 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: dipeptidyl peptidase 9 [Vicugna pacos]
ENSG00000142039(CCDC97)	--	19.321026	1149	20.88875024	1298	20.640656	1214	19.557987	1020	21.95309	1293	26.76049	1526	0.959145231	-0.202354493	normal	0.981827918	-0.026963191	normal	0.890147592	0.321337328	normal	0.907178732	0.048484129	normal	--	--	--	--	--	[S]	Function unknown	Coiled-coil domain containing protein (DUF2052)	Coiled-coil domain-containing protein 97 GN=CCDC97 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 97 [Ceratotherium simum simum]
ENSG00000142046(TMEM91)	--	45.84490628	1578	37.2588835	1346	43.196481	1547	32.6843486	1200	38.38129022	1274	40.637127	1408	0.647938365	-0.425418362	normal	0.978600127	-0.100623464	normal	0.976200641	-0.143969721	normal	0.20998355	-0.224367716	normal	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced transmembrane protein	Transmembrane protein 91 GN=TMEM91 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 91 isoform X3 [Galeopterus variegatus]
ENSG00000142065(ZFP14)	--	3.825693	335	4.364486	391	4.512165922	381	2.239654	258	2.45882974	270	3.33525655	324	0.766152159	-0.405496186	normal	0.314590537	-0.553045936	normal	0.931050937	-0.24104988	normal	0.092890094	-0.39818588	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101142137|ZFP14; zinc finger protein 14 homolog; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain;; Uncharacterised protein (DUF2406)"	Zinc finger protein 14 homolog GN=ZFP14 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 14 homolog isoform X1 [Equus caballus]
ENSG00000142082(SIRT3)	--	13.00959925	446	11.47311717	394	10.02514192	409	12.2053718	389	11.10538417	384	13.48759913	430	0.936724234	-0.227266659	normal	0.96713812	-0.058289241	normal	0.968361498	0.063714595	normal	0.82445739	-0.075061738	normal	[K]	Transcription	Molecular Function: NAD+ binding (GO:0070403);; 	K11413|0|ptr:450911|SIRT3; sirtuin 3; K11413 NAD-dependent deacetylase sirtuin 3 [EC:3.5.1.-] (A)	Central carbon metabolism in cancer (ko05230)	[BK]	Chromatin structure and dynamics;; Transcription	Sir2 family	"NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Precursor) GN=SIRT3 OS=Homo sapiens (Human) PE=1 SV=2"	BK	Chromatin structure and dynamics;; Transcription	"PREDICTED: NAD-dependent protein deacetylase sirtuin-3, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000142089(IFITM3)	--	8.635405	49	6.82526669	37	5.202062261	34	23.80860171	187	31.93260229	231	23.63390261	181	2.24E-10	1.869208736	up	0	2.572980014	up	1.44E-14	2.353522825	up	1.93E-14	2.298022707	up	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06566|2.91608e-83|hsa:10410|IFITM3, 1-8U, DSPA2b, IP15; interferon induced transmembrane protein 3; K06566 interferon induced transmembrane protein (A)"	--	--	--	Interferon-induced transmembrane protein	Interferon-induced transmembrane protein 3 GN=IFITM3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: interferon-induced transmembrane protein 3-like [Ceratotherium simum simum]
ENSG00000142102(PGGHG)	--	7.77994386	711	6.353958955	560	5.623284629	546	2.636149208	234	4.140800425	345	3.746106158	347	7.77E-16	-1.627711821	down	0.014589619	-0.717762027	normal	0.041592849	-0.659943821	normal	3.66E-05	-0.992665027	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 65 central catalytic domain	Acid trehalase-like protein 1 GN=ATHL1 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: acid trehalase-like protein 1 [Galeopterus variegatus]
ENSG00000142149(HUNK)	--	0.545604472	74	0.8204937	93	1.753565	68	1.49639202	102	0.56065	84	0.500398	62	0.906397482	0.424603801	normal	0.964673428	-0.16543584	normal	0.972763072	-0.138334824	normal	0.947441852	0.054622643	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K08797|0|hsa:30811|HUNK; hormonally up-regulated Neu-associated kinase (EC:2.7.11.1); K08797 hormonally upregulated Neu-associated kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family	Hormonally up-regulated neu tumor-associated kinase GN=HUNK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: hormonally up-regulated neu tumor-associated kinase [Ceratotherium simum simum]
ENSG00000142156(COL6A1)	--	13.11442003	1254	9.256482019	898	13.0727246	1287	11.88552054	1138	10.58512217	1011	8.824012706	850	0.968569791	-0.17064945	normal	0.968436168	0.149331976	normal	0.055608182	-0.605886255	normal	0.508742812	-0.219169607	normal	--	--	--	"K06238|0|hsa:1291|COL6A1, OPLL; collagen, type VI, alpha 1; K06238 collagen, type VI, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974)	[W]	Extracellular structures	von Willebrand factor type A domain;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; von Willebrand factor type A domain	Collagen alpha-1(VI) chain (Precursor) GN=COL6A1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	Collagen alpha-1(VI) chain [Myotis davidii]
ENSG00000142166(IFNAR1)	--	16.586805	1206	13.04709	1221	11.50195	1098	19.980417	1271	12.98932	1089	16.23433	1501	0.981289027	0.044846205	normal	0.964429393	-0.186241388	normal	0.581296203	0.442231495	normal	0.691381908	0.11041928	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05130|0|hsa:3454|IFNAR1, AVP, IFN-alpha-REC, IFNAR, IFNBR, IFRC; interferon (alpha, beta and omega) receptor 1; K05130 interferon receptor 1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	"Interferon-alpha/beta receptor, fibronectin type III;; Tissue factor;; Fibronectin type III domain"	Interferon alpha/beta receptor 1 (Precursor) GN=IFNAR1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: interferon alpha/beta receptor 1 [Dasypus novemcinctus] 
ENSG00000142168(SOD1)	--	136.465087	2087	132.2040073	2097	143.022005	2231	149.082007	2317	134.2250051	2035	124.498471	1908	0.983705538	0.119911376	normal	0.98574307	-0.064677274	normal	0.962948025	-0.233749263	normal	0.824138446	-0.056973342	normal	[P]	Inorganic ion transport and metabolism	Biological Process: superoxide metabolic process (GO:0006801);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K04565|1.11188e-106|ptr:449637|SOD1; superoxide dismutase 1, soluble (EC:1.15.1.1); K04565 superoxide dismutase, Cu-Zn family [EC:1.15.1.1] (A)"	Peroxisome (ko04146);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Prion diseases (ko05020)	[P]	Inorganic ion transport and metabolism	Copper/zinc superoxide dismutase (SODC)	Superoxide dismutase [Cu-Zn] GN=SOD1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: superoxide dismutase [Cu-Zn] isoform X2 [Lipotes vexillifer]
ENSG00000142173(COL6A2)	--	17.6017103	1399	10.1710157	824	15.1387662	1249	8.839642685	706	10.26741734	818	5.153653583	414	4.01E-07	-1.015884999	down	0.976333199	-0.031911271	normal	0	-1.597827525	down	0.050704115	-0.863248863	normal	--	--	--	"K06238|0|hsa:1292|COL6A2, PP3610; collagen, type VI, alpha 2; K06238 collagen, type VI, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974)	[W]	Extracellular structures	von Willebrand factor type A domain;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; von Willebrand factor type A domain	Collagen alpha-2(VI) chain (Precursor) GN=COL6A2 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: collagen alpha-2(VI) chain [Oryctolagus cuniculus]
ENSG00000142178(SIK1)	--	0.108662	9	0.258732	22	0.162063	13	0.313568	26	0.386006	32	0.143325	12	0.750416596	1.358228544	normal	0.970124909	0.491021238	normal	--	--	--	0.486892398	0.646618964	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16311|0|hsa:150094|SIK1, MSK, SIK, SNF1LK; salt-inducible kinase 1 (EC:2.7.11.1); K19008 serine/threonine-protein kinase SIK1 [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase SIK1 GN=SIK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase SIK1 [Equus caballus]
ENSG00000142185(TRPM2)	--	0.12234172	7	0.088379715	3	0.028811537	0	6.98928136	240	5.744127861	200	5.158560086	174	0	4.794499119	up	0	5.463112974	up	0	6.854590708	up	5.36E-44	5.915548974	up	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04977|0|hsa:7226|TRPM2, EREG1, KNP3, LTRPC2, NUDT9H, NUDT9L1, TRPC7; transient receptor potential cation channel, subfamily M, member 2 (EC:3.6.1.13); K04977 transient receptor potential cation channel subfamily M member 2 (A)"	Oxytocin signaling pathway (ko04921)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein	Transient receptor potential cation channel subfamily M member 2 GN=TRPM2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily M member 2 [Galeopterus variegatus]
ENSG00000142186(SCYL1)	--	23.9260991	1390	21.5238838	1262	22.4950674	1327	20.66155766	1196	23.8131145	1372	20.95579151	1226	0.945926391	-0.247404589	normal	0.978779181	0.099028182	normal	0.976699534	-0.122355721	normal	0.702729371	-0.089713348	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08876|0|hsa:57410|SCYL1, GKLP, NKTL, NTKL, P105, TAPK, TEIF, TRAP; SCY1-like 1 (S. cerevisiae); K08876 SCY1-like protein 1 (A)"	--	[R]	General function prediction only	Protein kinase domain;; HEAT repeat;; Protein tyrosine kinase	N-terminal kinase-like protein GN=HT019 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	hypothetical protein TREES_T100019408 [Tupaia chinensis]
ENSG00000142188(TMEM50B)	--	9.54348	288	9.34338	283	8.6701	258	11.9013	364	12.11930334	366	10.4489	316	0.892301581	0.305584601	normal	0.850493614	0.347975993	normal	0.911648293	0.282762036	normal	0.224638275	0.313696403	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised protein family (UPF0220)	Transmembrane protein 50B GN=TMEM50B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	transmembrane protein 50B [Oryctolagus cuniculus] 
ENSG00000142192(APP)	--	239.7807192	18206	236.8560157	18117	213.3787292	16255	241.0824222	18311	242.5203891	18274	277.5850178	21054	0.997731536	-0.022533771	normal	0.997622423	-0.00897743	normal	0.962801811	0.364889447	normal	0.666965354	0.111607565	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Molecular Function: heparin binding (GO:0008201);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transition metal ion binding (GO:0046914);; 	"K04520|0|hsa:351|APP, AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2; amyloid beta (A4) precursor protein; K04520 amyloid beta A4 protein (A)"	Serotonergic synapse (ko04726);; Alzheimer's disease (ko05010)	[R]	General function prediction only	"E2 domain of amyloid precursor protein;; Amyloid A4 N-terminal heparin-binding;; beta-amyloid precursor protein C-terminus;; Beta-amyloid peptide (beta-APP);; Copper-binding of amyloid precursor, CuBD;; Kunitz/Bovine pancreatic trypsin inhibitor domain"	C31 (Precursor) GN=APP OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	"PREDICTED: amyloid beta A4 protein, partial [Galeopterus variegatus]"
ENSG00000142197(DOPEY2)	--	3.982722	473	2.368499355	377	3.569769	406	2.243410982	361	3.788922	352	1.829837	281	0.695338742	-0.419109844	normal	0.961197916	-0.119917698	normal	0.346500477	-0.536783807	normal	0.119513166	-0.359427719	normal	[K]	Transcription	--	--	--	[K]	Transcription	"Dopey, N-terminal"	Protein dopey-2 GN=DOPEY2 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: protein dopey-2 [Tupaia chinensis]
ENSG00000142207(URB1)	--	19.71978992	2099	18.2200692	1816	20.38015774	2159	19.84775841	1884	19.98161629	2017	15.9504043	1705	0.974060805	-0.186591204	normal	0.980906834	0.129917634	normal	0.869303568	-0.3486075	normal	0.50514576	-0.136885722	normal	--	--	--	"K14861|0|hsa:9875|URB1, C21orf108, NPA1; URB1 ribosome biogenesis 1 homolog (S. cerevisiae); K14861 nucleolar pre-ribosomal-associated protein 1 (A)"	--	[S]	Function unknown	Ribosome 60S biogenesis N-terminal	Nucleolar pre-ribosomal-associated protein 1 GN=URB1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: nucleolar pre-ribosomal-associated protein 1 isoform X1 [Equus caballus]
ENSG00000142208(AKT1)	--	61.21849771	3347	53.60989724	2975	55.57471328	3158	64.73574902	3564	67.05606149	3655	53.44780162	2910	0.990566302	0.059769932	normal	0.959117514	0.275428676	normal	0.986628583	-0.126220473	normal	0.756761838	0.073840885	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04456|0|pps:100969444|AKT1; v-akt murine thymoma viral oncogene homolog 1; K04456 RAC serine/threonine-protein kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Tight junction (ko04530);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Carbohydrate digestion and absorption (ko04973);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PH domain;; Kinase-like;; Protein kinase C terminal domain	RAC-alpha serine/threonine-protein kinase GN=AKT1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: RAC-alpha serine/threonine-protein kinase [Galeopterus variegatus]
ENSG00000142227(EMP3)	--	252.356155	2515	255.049609	2472	249.9258576	2622	254.0023948	2451	188.0336453	1884	204.9819126	2135	0.987680816	-0.06797811	normal	0.741403683	-0.413015929	normal	0.92967982	-0.304528051	normal	0.133630162	-0.25557368	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Epithelial membrane protein 3 GN=EMP3 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: epithelial membrane protein 3 [Tupaia chinensis] 
ENSG00000142230(SAE1)	--	105.560281	4139	111.74239	4472	122.2751872	4647	116.350485	4531	107.980613	4189	102.011167	4014	0.990972771	0.099679608	normal	0.990064675	-0.115700426	normal	0.980180502	-0.219473547	normal	0.740304548	-0.079621581	normal	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	K10684|0|ptr:456159|SAE1; SUMO1 activating enzyme subunit 1; K10684 ubiquitin-like 1-activating enzyme E1 A [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	ThiF family	"SUMO-activating enzyme subunit 1, N-terminally processed GN=SAE1 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: SUMO-activating enzyme subunit 1 [Galeopterus variegatus]
ENSG00000142233(NTN5)	--	0.885732853	14	0.569251245	17	0.139827061	3	0.293147282	8	0.250071222	6	0.301831009	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	UNC-6/NTR/C345C module;; Laminin EGF-like (Domains III and V)	Netrin-5 (Precursor) GN=NTN5 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: netrin-5 [Odobenus rosmarus divergens]
ENSG00000142235(LMTK3)	--	6.825379142	712	5.336210769	553	4.949824951	541	2.262401513	220	2.635423583	267	2.557805199	254	0	-1.718135063	down	2.93E-06	-1.067568317	down	1.12E-06	-1.094518488	down	2.96E-09	-1.306172604	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08899|0|hsa:114783|LMTK3, LMR3, PPP1R101, TYKLM3; lemur tyrosine kinase 3 (EC:2.7.11.1); K08899 lemur tyrosine kinase 3 [EC:2.7.10.1] (A)"	--	--	--	Protein tyrosine kinase;; Protein kinase domain	Serine/threonine-protein kinase LMTK3 (Precursor) GN=LMTK3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: lemur tyrosine kinase 3 [Ceratotherium simum simum]
ENSG00000142273(CBLC)	--	0	0	0.038795963	1	0.0335583	0	0	0	0	0	0.038974369	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: nucleus (GO:0005634);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Molecular Function: metal ion binding (GO:0046872);; 	"K04707|0|mcf:102135911|CBLC; Cbl proto-oncogene C, E3 ubiquitin protein ligase; K04707 E3 ubiquitin-protein ligase CBL [EC:6.3.2.19] (A)"	ErbB signaling pathway (ko04012);; Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; Jak-STAT signaling pathway (ko04630);; T cell receptor signaling pathway (ko04660);; Insulin signaling pathway (ko04910);; Bacterial invasion of epithelial cells (ko05100);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Chronic myeloid leukemia (ko05220)	[V]	Defense mechanisms	"CBL proto-oncogene N-terminus, SH2-like domain;; CBL proto-oncogene N-terminus, EF hand-like domain;; CBL proto-oncogene N-terminal domain 1;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase CBL-C GN=CBLC OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: E3 ubiquitin-protein ligase CBL-C [Galeopterus variegatus]
ENSG00000142303(ADAMTS10)	--	3.715803929	337	4.247669089	389	3.158468494	300	5.881075897	544	7.659092691	721	8.807833182	810	0.04461998	0.657645489	normal	0.000293122	0.866291529	normal	1.36E-12	1.420133216	up	0.000371534	0.99574075	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; 	"K08625|0|ptr:455676|ADAMTS10; ADAM metallopeptidase with thrombospondin type 1 motif, 10; K08625 a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease;; ADAM-TS Spacer 1;; Thrombospondin type 1 domain;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; PLAC (protease and lacunin) domain;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 10 (Precursor) GN=ADAMTS10 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 10 isoform X1 [Oryctolagus cuniculus]
ENSG00000142319(SLC6A3)	--	0	0	0	0	0.0262771	1	0.0270608	2	0.0393171	2	0.0400644	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05036|0|hsa:6531|SLC6A3, DAT, DAT1, PKDYS; solute carrier family 6 (neurotransmitter transporter), member 3; K05036 solute carrier family 6 (neurotransmitter transporter, dopamine) member 3 (A)"	Dopaminergic synapse (ko04728);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium-dependent dopamine transporter GN=SLC6A3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent dopamine transporter [Elephantulus edwardii]
ENSG00000142327(RNPEPL1)	--	25.79532315	1630	24.77374398	1730	21.9783841	1628	18.49857502	1264	18.06145344	1161	23.55893482	1442	0.743457364	-0.397281181	normal	0.073965206	-0.596189924	normal	0.970386227	-0.183140094	normal	0.012212603	-0.388152095	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	K09605|0|hsa:57140|RNPEPL1; arginyl aminopeptidase (aminopeptidase B)-like 1; K09605 arginyl aminopeptidase-like 1 [EC:3.4.11.-] (A)	--	[IOVE]	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms;; Amino acid transport and metabolism"	"Peptidase family M1;; Leukotriene A4 hydrolase, C-terminal;; Peptidase MA superfamily"	Arginyl aminopeptidase-like 1 GN=RNPEPL1 OS=Homo sapiens (Human) PE=2 SV=2	EIOV	"Amino acid transport and metabolism;; Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms"	PREDICTED: arginyl aminopeptidase-like 1 [Odobenus rosmarus divergens]
ENSG00000142330(CAPN10)	--	10.98733993	487	9.499437086	478	12.17400138	583	5.873394516	284	5.757831962	251	6.726381403	332	0.002583761	-0.805492051	normal	0.000129976	-0.946542796	normal	0.001261531	-0.817755354	normal	4.43E-06	-0.856724608	normal	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K08579|0|hsa:11132|CAPN10, CANP10, NIDDM1; calpain 10; K08579 calpain-10 [EC:3.4.22.-] (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III"	Calpain-10 GN=CAPN10 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-10 [Ceratotherium simum simum]
ENSG00000142347(MYO1F)	--	0.257639704	24	0.08481552	8	0.24864166	23	0.15010046	14	0.135074831	12	0.09564324	9	0.965120419	-0.745280728	normal	--	--	--	0.870332851	-1.228867774	normal	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	K10356|0|hsa:4542|MYO1F; myosin IF; K10356 myosin I (A)	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Unconventional myosin-If GN=MYO1F OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: unconventional myosin-If [Ceratotherium simum simum]
ENSG00000142396(ERVK3-1)	--	28.13746445	674	30.17830233	770	28.12740804	721	31.5174633	815	32.29387585	777	33.617563	858	0.935945376	0.242715469	normal	0.975995156	-0.008354072	normal	0.937569031	0.24222067	normal	0.487042359	0.157324372	normal	--	--	--	--	--	--	--	--	Periphilin-1 GN=PPHLN1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: periphilin-1-like [Myotis brandtii]
ENSG00000142405(NLRP12)	--	0.013911212	1	0.024775564	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	NACHT domain;; PAAD/DAPIN/Pyrin domain;; Fish-specific NACHT associated domain;; Leucine Rich repeat;; Leucine Rich repeats (2 copies)	"NACHT, LRR and PYD domains-containing protein 12 GN=NLRP12 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: NACHT, LRR and PYD domains-containing protein 12 [Ceratotherium simum simum]"
ENSG00000142409(ZNF787)	--	41.97633861	1274	40.06370985	1238	36.159327	1130	37.62949995	1165	40.744503	1245	36.746826	1134	0.970893586	-0.159666126	normal	0.981529731	-0.013275959	normal	0.981025348	-0.003189314	normal	0.816543769	-0.060756342	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; LYAR-type C2HC zinc finger;; XPA protein N-terminal"	Zinc finger protein 787 GN=ZNF787 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 787 [Ochotona princeps]
ENSG00000142444(TIMM29)	--	8.57632	220	8.25489	211	9.65282	244	9.35853	249	8.57315	222	9.25007	238	0.957437514	0.146845594	normal	0.964798819	0.051530048	normal	0.966346249	-0.043935289	normal	0.913836245	0.049761148	normal	--	--	Cellular Component: mitochondrial inner membrane protein insertion complex (GO:0042721);; 	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2366)	Uncharacterized protein C19orf52 GN=C19orf52 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	uncharacterized protein C19orf52 homolog [Bos taurus] 
ENSG00000142449(FBN3)	--	0	0	0	0	0	0	0	0	0.005302634	0	0.005408222	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; TB domain;; EGF-like domain;; Coagulation Factor Xa inhibitory site;; EGF domain	Fibrillin-3 (Precursor) GN=FBN3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: fibrillin-3 [Galeopterus variegatus]
ENSG00000142453(CARM1)	--	28.60275209	1312	32.49633807	1148	27.43673378	1193	32.41666546	1253	25.07374101	1246	22.84706382	1106	0.978982431	-0.097097197	normal	0.977734634	0.096632661	normal	0.975801448	-0.117379522	normal	0.887026098	-0.040639456	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K05931|0|hsa:10498|CARM1, PRMT4; coactivator-associated arginine methyltransferase 1 (EC:2.1.1.125); K05931 histone-arginine methyltransferase CARM1 [EC:2.1.1.125] (A)"	--	[OK]	"Posttranslational modification, protein turnover, chaperones;; Transcription"	Coactivator-associated arginine methyltransferase 1 N terminal;; PRMT5 arginine-N-methyltransferase;; Methyltransferase domain;; Ribosomal protein L11 methyltransferase (PrmA);; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase small domain;; Protein of unknown function (DUF1698);; Methyltransferase domain	Histone-arginine methyltransferase CARM1 GN=CARM1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: histone-arginine methyltransferase CARM1 [Orycteropus afer afer]
ENSG00000142459(EVI5L)	--	3.68435997	289	1.981561063	160	3.248335782	256	2.546793983	201	3.161197093	247	2.745969201	215	0.402979041	-0.551171335	normal	0.334478979	0.600412199	normal	0.928109842	-0.258430508	normal	0.843804337	-0.10916245	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	EVI5-like protein GN=EVI5L OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: EVI5-like protein isoform X2 [Pteropus alecto]
ENSG00000142484(TM4SF5)	--	0	0	0	0	0	0	0.137576	1	0.140767	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	L6 membrane protein	Transmembrane 4 L6 family member 5 GN=TM4SF5 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane 4 L6 family member 5 [Tupaia chinensis] 
ENSG00000142494(SLC47A1)	--	19.36048966	947	19.29435281	993	20.02031741	1004	10.98553254	556	11.43606333	559	13.66025005	701	0.000724918	-0.797401866	normal	0.00022596	-0.848624556	normal	0.245376242	-0.525611629	normal	3.19E-06	-0.717471258	normal	[V]	Defense mechanisms	Biological Process: drug transmembrane transport (GO:0006855);; Molecular Function: drug transmembrane transporter activity (GO:0015238);; Molecular Function: antiporter activity (GO:0015297);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K03327|0|hsa:55244|SLC47A1, MATE1; solute carrier family 47 (multidrug and toxin extrusion), member 1; K03327 multidrug resistance protein, MATE family (A)"	--	[R]	General function prediction only	MatE	Multidrug and toxin extrusion protein 1 GN=SLC47A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: multidrug and toxin extrusion protein 2-like [Ceratotherium simum simum]
ENSG00000142507(PSMB6)	--	190.5290089	2186	202.6610075	2400	204.6572	2435	184.0520073	2163	173.3240091	1973	149.98382	1739	0.987104777	-0.046059454	normal	0.928718819	-0.30385845	normal	0.382043397	-0.493590766	normal	0.093448386	-0.278838962	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02738|1.46228e-137|pps:100985958|PSMB6; proteasome (prosome, macropain) subunit, beta type, 6; K02738 20S proteasome subunit beta 1 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-6 (Precursor) GN=PSMB6 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-6 isoform X2 [Canis lupus familiaris]
ENSG00000142512(SIGLEC10)	--	0.02540797	1	0.055755099	2	0	0	0	0	0	0	0.03213151	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06749|0|pps:100984414|SIGLEC10; sialic acid binding Ig-like lectin 10; K06749 sialic acid binding Ig-like lectin 10 (A)	--	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Sialic acid-binding Ig-like lectin 10 (Precursor) GN=SIGLEC10 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: sialic acid-binding Ig-like lectin 10 [Ceratotherium simum simum]
ENSG00000142528(ZNF473)	--	4.05723328	371	3.69996179	319	3.76912094	297	3.5475517	341	4.3181126	376	2.437700889	234	0.957038396	-0.1518236	normal	0.940321422	0.214810841	normal	0.858920646	-0.350231803	normal	0.874698386	-0.075909909	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:25888|ZNF473, HZFP100, ZN473; zinc finger protein 473; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box"	Zinc finger protein 473 GN=ZNF473 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 473 [Galeopterus variegatus]
ENSG00000142530(FAM71E1)	--	1.307465	25	1.097864678	20	1.166706	22	1.557301	30	1.03585	19	2.019801	39	0.983950897	0.219856072	normal	0.988135588	-0.088556171	normal	0.902052039	0.777074593	normal	0.654520284	0.372839128	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3699)	Protein FAM71E1 GN=FAM71E1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM71E1 isoform X1 [Bos taurus]
ENSG00000142534(RPS11)	--	2287.593047	16940	2226.348391	16756	2233.22777	17011	2036.207697	15753	2128.163552	15676	2008.254493	15177	0.996350244	-0.135626776	normal	0.996524694	-0.117535899	normal	0.995219554	-0.172856471	normal	0.549922052	-0.142940783	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02949|1.06881e-112|umr:103657127|RPS11; ribosomal protein S11; K02949 small subunit ribosomal protein S11e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S17	40S ribosomal protein S11 GN=RPS11 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S11 [Camelus dromedarius]
ENSG00000142541(RPL13A)	--	2068.927643	44660	1825.776757	40090	1849.378151	40975	2018.887448	44275	2104.864962	45235	2025.557246	44472	0.998909329	-0.043321711	normal	0.99811242	0.152765069	normal	0.998566521	0.109858003	normal	0.829100354	0.070569253	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02872|3.77747e-130|ptr:456207|RPL13A; ribosomal protein L13a; K02872 large subunit ribosomal protein L13Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L13	60S ribosomal protein L13a GN=RPL13A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L13a isoform X2 [Camelus ferus] 
ENSG00000142544(CTU1)	--	9.239380652	352	9.730300375	371	9.021760802	374	8.5249075	334	9.774410603	350	10.02435131	372	0.963296822	-0.106084139	normal	0.962855192	-0.105049868	normal	0.969136757	-0.015962373	normal	0.831092618	-0.075762409	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	"K14168|3.33228e-154|hsa:90353|CTU1, ATPBD3, NCS6; cytosolic thiouridylase subunit 1; K14168 cytoplasmic tRNA 2-thiolation protein 1 [EC:2.7.7.-] (A)"	Sulfur relay system (ko04122)	[R]	General function prediction only	PP-loop family	Cytoplasmic tRNA 2-thiolation protein 1 {ECO:0000255|HAMAP-Rule:MF_03053} OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cytoplasmic tRNA 2-thiolation protein 1 [Bubalus bubalis]
ENSG00000142546(NOSIP)	--	44.23683667	796	39.35527012	716	48.192666	881	45.1307721	816	45.80334	806	38.07371	690	0.977020599	0.004959004	normal	0.965050003	0.149096759	normal	0.811740056	-0.36013675	normal	0.79583903	-0.071027452	normal	--	--	--	K13125|0|pon:100435614|NOSIP; nitric oxide synthase interacting protein; K13125 nitric oxide synthase-interacting protein (A)	--	[S]	Function unknown	Rtf2 RING-finger;; U-box domain;; Zinc-finger of the MIZ type in Nse subunit	Nitric oxide synthase-interacting protein GN=NOSIP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nitric oxide synthase-interacting protein [Sus scrofa]
ENSG00000142549(IGLON5)	--	0.265611	13	0.162334	8	0.237714	11	0.0610589	3	0.099134	4	0.0804859	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06773|0|pon:100443839|IGLON5; IgLON family member 5; K06773 opioid binding protein/cell adhesion molecule-like (A)	--	[T]	Signal transduction mechanisms	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	IgLON family member 5 (Precursor) GN=IGLON5 OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	"PREDICTED: igLON family member 5, partial [Ochotona princeps]"
ENSG00000142552(RCN3)	--	0.9854853	34	1.226389312	41	0.498429783	19	0.876962136	24	1.999083	39	1.1562079	34	0.968035971	-0.505979479	normal	0.979869589	-0.090165893	normal	0.924111161	0.784020644	normal	0.996295611	0.024134839	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair	Reticulocalbin-3 (Precursor) GN=RCN3 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: reticulocalbin-3 [Equus przewalskii]
ENSG00000142556(ZNF614)	--	3.61437993	308	3.136496489	256	3.374820175	285	4.329664255	370	3.362445238	276	3.768031333	326	0.934497886	0.232702433	normal	0.963056309	0.086605114	normal	0.949909481	0.184701604	normal	0.579236144	0.173539085	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:80110|ZNF614; zinc finger protein 614; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; zinc-finger;; Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7);; CpXC protein;; DNA directed RNA polymerase, 7 kDa subunit"	Zinc finger protein 614 GN=ZNF614 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 614 [Galeopterus variegatus]
ENSG00000142583(SLC2A5)	--	0.014545138	1	0	0	0.028321733	1	0.057821799	4	0.014182866	0	0.014457871	1	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08143|0|ptr:457916|SLC2A5; solute carrier family 2 (facilitated glucose/fructose transporter), member 5; K08143 MFS transporter, SP family, solute carrier family 2 (facilitated glucose/fructose transporter), member 5 (A)"	Carbohydrate digestion and absorption (ko04973)	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 5 GN=SLC2A5 OS=Homo sapiens (Human) PE=1 SV=1"	P	Inorganic ion transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 5 [Ailuropoda melanoleuca]"
ENSG00000142599(RERE)	--	25.18515798	1396	15.61123273	1907	16.97006914	1654	10.86821121	1324	8.84827849	1489	16.48577138	2111	0.978924887	-0.107107014	normal	0.813061798	-0.378047405	normal	0.875786187	0.343397327	normal	0.963294031	-0.02948814	normal	--	--	"Molecular Function: chromatin binding (GO:0003682);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K05628|0|pps:100967587|RERE; arginine-glutamic acid dipeptide (RE) repeats; K05628 arginine-glutamic acid dipeptide repeats protein (A)	--	[R]	General function prediction only	Atrophin-1 family;; BAH domain;; ELM2 domain;; GATA zinc finger	Arginine-glutamic acid dipeptide repeats protein GN=RERE OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: arginine-glutamic acid dipeptide repeats protein [Orycteropus afer afer]
ENSG00000142606(MMEL1)	--	7.49018	37	6.99806	36	8.52012	44	7.48307	39	12.0447	60	5.47968	28	0.98237778	0.043362703	normal	0.834512428	0.692780105	normal	0.927998772	-0.632881592	normal	0.922694728	0.097002494	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08635|0|hsa:79258|MMEL1, MMEL2, NEP2, NEPII, NL1, NL2, SEP; membrane metallo-endopeptidase-like 1 (EC:3.4.24.11); K08635 membrane metallo-endopeptidase-like 1 (A)"	--	[E]	Amino acid transport and metabolism	Peptidase family M13;; Peptidase family M13	"Membrane metallo-endopeptidase-like 1, soluble form GN=MMEL1 OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	PREDICTED: membrane metallo-endopeptidase-like 1 isoform X2 [Tupaia chinensis]
ENSG00000142609(CFAP74)	--	0.0078299	1	0.00774145	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Flagellar-associated PapD-like	Cilia- and flagella-associated protein 74 {ECO:0000312|HGNC:HGNC:29368} OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein LOC102502467 [Tupaia chinensis]
ENSG00000142611(PRDM16)	--	0.142530247	19	0.241052571	12	0.043761895	7	0.03926425	7	0.1912505	24	0.122413301	12	--	--	--	0.944988294	0.897328041	normal	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; BED zinc finger"	PR domain zinc finger protein 16 GN=PRDM16 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: PR domain zinc finger protein 16 [Tupaia chinensis]
ENSG00000142619(PADI3)	--	3.505159	235	1.768944411	119	2.834315	188	3.618622142	237	4.456549	292	1.846294466	121	0.966908946	-0.018485615	normal	1.19E-06	1.263003713	up	0.347432122	-0.63757212	normal	0.786144857	0.239829071	normal	--	--	Molecular Function: protein-arginine deiminase activity (GO:0004668);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein citrullination (GO:0018101);; 	"K01481|0|hsa:51702|PADI3, PAD3, PDI3; peptidyl arginine deiminase, type III (EC:3.5.3.15); K01481 protein-arginine deiminase [EC:3.5.3.15] (A)"	--	--	--	Protein-arginine deiminase (PAD);; Protein-arginine deiminase (PAD) middle domain;; Protein-arginine deiminase (PAD) N-terminal domain	Protein-arginine deiminase type-3 GN=PADI3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein-arginine deiminase type-3 [Canis lupus familiaris]
ENSG00000142621(FHAD1)	--	0.23131878	20	0.141095875	17	0.134659533	12	0.355530933	13	0.246874744	11	0.390077081	12	0.98129062	-0.595208085	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	FHA domain	Forkhead-associated domain-containing protein 1 GN=FHAD1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: forkhead-associated domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000142623(PADI1)	--	1.8314141	94	1.1212035	63	1.675143696	89	1.734931918	97	1.943637171	101	1.616914052	89	0.971459942	0.014262248	normal	0.676244831	0.647133579	normal	0.972000422	-0.008152908	normal	0.721808438	0.201302479	normal	--	--	Molecular Function: protein-arginine deiminase activity (GO:0004668);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein citrullination (GO:0018101);; 	"K01481|0|hsa:29943|PADI1, HPAD10, PAD1, PDI, PDI1; peptidyl arginine deiminase, type I (EC:3.5.3.15); K01481 protein-arginine deiminase [EC:3.5.3.15] (A)"	--	--	--	Protein-arginine deiminase (PAD);; Protein-arginine deiminase (PAD) middle domain;; Protein-arginine deiminase (PAD) N-terminal domain	Protein-arginine deiminase type-1 GN=PADI1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein-arginine deiminase type-1 [Galeopterus variegatus]
ENSG00000142627(EPHA2)	--	41.6099	3413	45.9179	3818	60.0599	5033	59.004	4822	53.0631	4332	52.7336	4338	0.585837205	0.467581114	normal	0.986663623	0.160729785	normal	0.980761845	-0.222607869	normal	0.715334529	0.116733602	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05103|0|hsa:1969|EPHA2, ARCC2, CTPA, CTPP1, CTRCT6, ECK; EPH receptor A2 (EC:2.7.10.1); K05103 Eph receptor A2 [EC:2.7.10.1] (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360)	[T]	Signal transduction mechanisms	"Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Interferon-alpha/beta receptor, fibronectin type III"	Ephrin type-A receptor 2 (Precursor) GN=EPHA2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 2 [Oryctolagus cuniculus]
ENSG00000142632(ARHGEF19)	--	3.219763291	117	3.973269166	151	3.774342095	145	3.316153733	114	4.4577015	157	2.794277172	112	0.96854548	-0.067410116	normal	0.966075418	0.034451077	normal	0.895655728	-0.376366604	normal	0.800386331	-0.129767138	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Rho guanine nucleotide exchange factor 19 GN=ARHGEF19 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 19 [Galeopterus variegatus]
ENSG00000142634(EFHD2)	--	107.7476751	5119	101.0900356	4933	113.510487	5597	90.162788	4315	61.76731498	2922	66.972897	3218	0.966772105	-0.277242939	normal	0.000767612	-0.776622577	normal	0.000216879	-0.806489724	normal	0.000617299	-0.603941402	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[R]	General function prediction only	EF-hand domain pair;; EF hand;; EF-hand domain	EF-hand domain-containing protein D2 GN=EFHD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: EF-hand domain-containing protein D2 [Bubalus bubalis]
ENSG00000142655(PEX14)	--	12.97648	369	8.96054	327	11.25168	382	11.06654	364	11.45723	334	10.13022	288	0.967894337	-0.050303737	normal	0.967405508	0.009089317	normal	0.734781069	-0.413901659	normal	0.62635848	-0.150382922	normal	--	--	--	K13343|0|ptr:457929|PEX14; peroxisomal biogenesis factor 14; K13343 peroxin-14 (A)	Peroxisome (ko04146)	[MOU]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Peroxisomal membrane anchor protein (Pex14p) conserved region	Peroxisomal membrane protein PEX14 GN=PEX14 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein PEX14 [Equus caballus] 
ENSG00000142657(PGD)	--	536.903248	19446	609.3742385	22229	514.8776063	18747	360.2035491	13085	367.9298006	13262	486.6858625	17581	0.15021367	-0.602333329	normal	0.002350153	-0.766502939	normal	0.99716134	-0.100925646	normal	0.012592067	-0.48046489	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Biological Process: pentose-phosphate shunt (GO:0006098);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00033|0|hsa:5226|PGD, 6PGD; phosphogluconate dehydrogenase (EC:1.1.1.44); K00033 6-phosphogluconate dehydrogenase [EC:1.1.1.44 1.1.1.343] (A)"	Pentose phosphate pathway (ko00030);; Glutathione metabolism (ko00480);; Carbon metabolism (ko01200)	[G]	Carbohydrate transport and metabolism	"6-phosphogluconate dehydrogenase, C-terminal domain;; NAD binding domain of 6-phosphogluconate dehydrogenase"	"6-phosphogluconate dehydrogenase, decarboxylating GN=PGD OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: 6-phosphogluconate dehydrogenase, decarboxylating [Elephantulus edwardii]"
ENSG00000142661(MYOM3)	--	4.41303204	674	3.983561166	601	4.041896	624	5.235496	783	4.778448	705	3.608682	554	0.957035233	0.185039842	normal	0.948104321	0.20834725	normal	0.955690933	-0.179489534	normal	0.779695264	0.082542785	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Tissue factor;; CD80-like C2-set immunoglobulin domain	Myomesin-3 GN=MYOM3 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: myomesin-3 [Equus caballus]
ENSG00000142675(CNKSR1)	--	0.069866618	4	0.14047258	8	0.135029742	7	0.214744601	12	0.03490127	1	0.017156	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[F]	Nucleotide transport and metabolism	Connector enhancer of kinase suppressor of ras;; PH domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Connector enhancer of kinase suppressor of ras 1 GN=CNKSR1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: connector enhancer of kinase suppressor of ras 1 isoform X1 [Galeopterus variegatus]
ENSG00000142676(RPL11)	--	886.1239855	7125	853.8569021	6939	845.3229752	6982	973.9192457	8332	889.1462302	7100	830.677213	6862	0.989744375	0.194901668	normal	0.994794482	0.011662187	normal	0.994802996	-0.033295398	normal	0.817737445	0.061279825	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02868|1.76917e-128|pale:102883699|RPL11; ribosomal protein L11; K02868 large subunit ribosomal protein L11e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	ribosomal L5P family C-terminus;; Ribosomal protein L5	60S ribosomal protein L11 GN=RPL11 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L11 [Pteropus alecto] 
ENSG00000142677(IL22RA1)	--	1.68336	100	1.507239	90	1.935699	116	1.294253857	76	1.3608097	80	0.788756	48	0.908461999	-0.419344533	normal	0.963456493	-0.187998673	normal	0.001508092	-1.255064559	down	0.146402093	-0.606884845	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05138|0|hsa:58985|IL22RA1, CRF2-9, IL22R, IL22R1; interleukin 22 receptor, alpha 1; K05138 interleukin 22 receptor alpha 1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	"Tissue factor;; Interferon-alpha/beta receptor, fibronectin type III"	Interleukin-22 receptor subunit alpha-1 (Precursor) GN=IL22RA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-22 receptor subunit alpha-1-like [Galeopterus variegatus]
ENSG00000142684(ZNF593)	--	28.1111	232	20.355197	171	24.809428	216	21.28670026	186	28.348992	235	21.5836	184	0.877729333	-0.347081212	normal	0.772490697	0.433951866	normal	0.938803637	-0.237810977	normal	0.911176091	-0.053907918	normal	[R]	General function prediction only	--	K14821|6.81641e-63|ptr:456653|ZNF593; zinc finger protein 593; K14821 bud site selection protein 20 (A)	--	[A]	RNA processing and modification	Zinc-finger double-stranded RNA-binding	Zinc finger protein 593 GN=ZNF593 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	hypothetical protein PANDA_001141 [Ailuropoda melanoleuca]
ENSG00000142686(C1orf216)	--	10.7946	586	10.57377	578	11.14764	616	8.41755	472	7.9791	429	8.82812	457	0.84158507	-0.341944791	normal	0.591813505	-0.450145803	normal	0.616103574	-0.437775063	normal	0.033866322	-0.411613235	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4653)	UPF0500 protein C1orf216 GN=C1orf216 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0500 protein C1orf216 homolog [Pteropus alecto] 
ENSG00000142687(KIAA0319L)	--	13.30059132	1427	12.95034837	1261	14.11072523	1481	13.27689388	1409	13.6464734	1406	15.64112151	1652	0.982683722	-0.049092791	normal	0.975410461	0.135447873	normal	0.97634481	0.149206283	normal	0.742874168	0.079078793	normal	[R]	General function prediction only	--	--	--	--	--	REJ domain;; Y_Y_Y domain;; PKD domain;; Bacterial Ig-like domain (group 3);; Domain of unknown function (DUF4625);; Putative Ig domain	Dyslexia-associated protein KIAA0319-like protein GN=KIAA0319L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: dyslexia-associated protein KIAA0319-like protein homolog isoform X1 [Galeopterus variegatus] 
ENSG00000142694(EVA1B)	--	14.846056	218	11.66608477	178	12.57903372	197	10.82105863	166	11.452554	169	11.44109357	170	0.802147123	-0.420568423	normal	0.962746212	-0.095448182	normal	0.945521585	-0.219139676	normal	0.488330055	-0.252824305	normal	--	--	--	--	--	--	--	FAM176 family	Protein eva-1 homolog B GN=EVA1B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein eva-1 homolog B [Galeopterus variegatus]
ENSG00000142700(DMRTA2)	--	0.055430727	2	0.079591692	3	0	0	0.257115358	11	0.316692	12	0.210228643	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	--	--	DM DNA binding domain;; DMRTA motif	Doublesex- and mab-3-related transcription factor A2 GN=DMRTA2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: doublesex- and mab-3-related transcription factor A2 [Chrysochloris asiatica]
ENSG00000142731(PLK4)	--	7.253292635	496	9.61661535	541	9.347504836	542	6.898519454	454	5.676200131	391	4.867124196	337	0.957975658	-0.157968381	normal	0.466869515	-0.488273412	normal	0.023072823	-0.691365833	normal	0.028722041	-0.43981707	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08863|0|ptr:461480|PLK4; polo-like kinase 4; K08863 polo-like kinase 4 [EC:2.7.11.21] (A)	FoxO signaling pathway (ko04068)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; POLO box duplicated region	Serine/threonine-protein kinase PLK4 GN=PLK4 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase PLK4 isoform X1 [Physeter catodon]
ENSG00000142733(MAP3K6)	--	3.282305195	267	3.543040634	293	2.797699191	235	1.9496886	157	2.028691518	161	2.333901895	170	0.021351859	-0.790897903	normal	0.003678529	-0.879050869	normal	0.696782265	-0.471831577	normal	0.003766093	-0.725346211	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04425|0|hsa:9064|MAP3K6, ASK2, MAPKKK6, MEKK6; mitogen-activated protein kinase kinase kinase 6 (EC:2.7.11.25); K04425 mitogen-activated protein kinase kinase kinase 6 [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4071);; Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase 6 GN=MAP3K6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 6 [Ceratotherium simum simum]
ENSG00000142751(GPN2)	--	7.736477	473	8.32211	475	5.450390347	411	8.762716	521	8.161475053	567	6.707320112	471	0.966041811	0.10827574	normal	0.935399364	0.233314053	normal	0.950549339	0.187651777	normal	0.488770315	0.176415104	normal	[R]	General function prediction only	--	"K06883|0|hsa:54707|GPN2, ATPBD1B; GPN-loop GTPase 2; K06883 (A)"	--	[R]	General function prediction only	Conserved hypothetical ATP binding protein	GPN-loop GTPase 2 {ECO:0000305} GN=ATPBD1B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: GPN-loop GTPase 2 [Mustela putorius furo] 
ENSG00000142765(SYTL1)	--	0.300146464	11	0.29099972	9	0.140836456	4	0.100070363	4	0.1155405	3	0.206066813	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17598|0|hsa:84958|SYTL1, JFC1, SLP1; synaptotagmin-like 1; K17598 synaptotagmin-like protein (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-like protein 1 GN=SYTL1 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-like 1 isoform X2 [Sus scrofa]
ENSG00000142784(WDTC1)	--	8.870767	788	6.95793358	629	7.65871	703	7.942319	720	7.91495188	710	8.070651	724	0.963188944	-0.160703026	normal	0.962517975	0.152986093	normal	0.975226226	0.034101278	normal	1	0.001811417	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11807|0|ptr:469244|WDTC1; WD and tetratricopeptide repeats 1; K11807 WD and tetratricopeptide repeats protein 1 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	WD and tetratricopeptide repeats protein 1 GN=WDTC1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD and tetratricopeptide repeats protein 1 isoform X1 [Camelus ferus]
ENSG00000142794(NBPF3)	--	4.339727976	307	4.22241111	241	4.426759171	305	3.700369849	262	4.924055	347	3.085319162	221	0.924791864	-0.258104017	normal	0.519222188	0.501838406	normal	0.635441598	-0.470302714	normal	0.903323627	-0.060638164	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220)	Neuroblastoma breakpoint family member 3 GN=NBPF3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"TPA: neuroblastoma breakpoint family, member 3-like [Bos taurus]"
ENSG00000142798(HSPG2)	--	21.44645903	6550	17.40857782	5436	21.885163	6933	35.65027125	10951	32.96499056	10071	20.75075719	6478	0.005923586	0.710533339	normal	5.23E-05	0.867982934	normal	0.99340108	-0.106198764	normal	0.160008173	0.517297044	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06255|0|hsa:3339|HSPG2, HSPG, PLC, PRCAN, SJA, SJS, SJS1; heparan sulfate proteoglycan 2; K06255 heparan sulfate proteoglycan 2 (perlecan) (A)"	ECM-receptor interaction (ko04512);; Hepatitis B (ko05161);; Proteoglycans in cancer (ko05205)	[O]	"Posttranslational modification, protein turnover, chaperones"	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Laminin G domain;; Laminin B (Domain IV);; Laminin G domain;; Laminin EGF-like (Domains III and V);; Low-density lipoprotein receptor domain class A;; Concanavalin A-like lectin/glucanases superfamily;; Immunoglobulin C2-set domain;; EGF-like domain;; Alphaherpesvirus glycoprotein I;; Natural killer cell receptor 2B4	LG3 peptide (Precursor) GN=HSPG2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: basement membrane-specific heparan sulfate proteoglycan core protein [Galeopterus variegatus]
ENSG00000142856(ITGB3BP)	--	19.950889	302	22.023924	303	24.076709	327	19.211815	305	17.143062	269	18.20301	275	0.967744865	-0.016488102	normal	0.947019238	-0.192119778	normal	0.924887343	-0.256853425	normal	0.629022553	-0.15597039	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: CENP-A containing nucleosome assembly (GO:0034080);; "	"K11510|2.37578e-157|hsa:23421|ITGB3BP, CENP-R, CENPR, HSU37139, NRIF3, TAP20; integrin beta 3 binding protein (beta3-endonexin); K11510 centromere protein R (A)"	--	--	--	"Kinetochore component, CENP-R;; Putative binding domain"	Centromere protein R GN=ITGB3BP OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: centromere protein R isoform X2 [Galeopterus variegatus]
ENSG00000142864(SERBP1)	--	111.0759054	5604	110.25351	5725	121.0522052	6046	135.3538055	6829	123.4777059	6121	103.2958154	5138	0.978836107	0.25432187	normal	0.993333323	0.075045944	normal	0.979519329	-0.242999519	normal	0.898038535	0.036102995	normal	--	--	--	K13199|5.06992e-166|mcf:101926017|uncharacterized LOC101926017; K13199 plasminogen activator inhibitor 1 RNA-binding protein (A)	--	[R]	General function prediction only	Hyaluronan / mRNA binding family	Plasminogen activator inhibitor 1 RNA-binding protein GN=SERBP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: plasminogen activator inhibitor 1 RNA-binding protein isoform X1 [Condylura cristata]
ENSG00000142867(BCL10)	--	7.405958	262	8.57595	251	7.83442	253	9.12656	329	9.663583	326	8.388685	316	0.902017886	0.296136097	normal	0.849694069	0.353882509	normal	0.892445277	0.310830051	normal	0.22373862	0.320809498	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K07368|1.09282e-136|pps:100977717|BCL10; B-cell CLL/lymphoma 10; K07368 B-cell CLL/lymphoma 10 (A)	NF-kappa B signaling pathway (ko04064);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Tuberculosis (ko05152)	--	--	Caspase recruitment domain	B-cell lymphoma/leukemia 10 GN=BCL10 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: B-cell lymphoma/leukemia 10 [Tupaia chinensis]
ENSG00000142871(CYR61)	--	17.9431	689	31.1656	1215	46.0914	1786	48.622	1875	29.8689	1142	35.028	1348	1.52E-14	1.411497459	up	0.976347184	-0.110678096	normal	0.698208226	-0.413798335	normal	0.788527221	0.221032529	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	"K06829|0|hsa:3491|CYR61, CCN1, GIG1, IGFBP10; cysteine-rich, angiogenic inducer, 61; K06829 cysteine rich protein 61 (A)"	--	--	--	Cystine-knot domain;; Insulin-like growth factor binding protein;; von Willebrand factor type C domain;; Thrombospondin type 1 domain	Protein CYR61 (Precursor) GN=CYR61 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: protein CYR61 [Balaenoptera acutorostrata scammoni]
ENSG00000142875(PRKACB)	--	9.751825751	623	12.2276228	750	12.01259349	756	11.62675514	703	9.870108182	627	9.914048618	633	0.96457851	0.143127846	normal	0.912553495	-0.279234965	normal	0.922948644	-0.263894472	normal	0.568621049	-0.138520745	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04345|0|nle:100583577|PRKACB; protein kinase, cAMP-dependent, catalytic, beta; K04345 protein kinase A [EC:2.7.11.11] (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Vasopressin-regulated water reabsorption (ko04962);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Bile secretion (ko04976);; Parkinson's disease (ko05012);; Prion diseases (ko05020);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Amoebiasis (ko05146);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	cAMP-dependent protein kinase catalytic subunit beta GN=PRKACB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cAMP-dependent protein kinase catalytic subunit beta isoform X1 [Orycteropus afer afer]
ENSG00000142892(PIGK)	--	12.845419	793	10.37241684	666	14.23355305	804	12.50134939	819	12.25560626	746	12.18107545	763	0.976931356	0.015680428	normal	0.965164505	0.141922287	normal	0.973823776	-0.083642365	normal	0.957142353	0.019632619	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; 	"K05290|0|ptr:456962|PIGK; phosphatidylinositol glycan anchor biosynthesis, class K; K05290 phosphatidylinositol glycan, class K [EC:2.6.-.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase C13 family	GPI-anchor transamidase (Precursor) GN=PIGK OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: GPI-anchor transamidase [Ceratotherium simum simum]
ENSG00000142910(TINAGL1)	--	0	0	0.100357834	4	0.059078739	1	0.061603653	2	0.15063297	4	0.263503636	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	--	--	[R]	General function prediction only	Papain family cysteine protease	Tubulointerstitial nephritis antigen-like (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tubulointerstitial nephritis antigen-like isoform X1 [Ochotona princeps]
ENSG00000142920(AZIN2)	--	0.767811366	26	0.9642734	34	0.587811162	19	0.95321334	32	1.4667285	46	0.775582318	28	0.982304632	0.255121364	normal	0.963553907	0.399353029	normal	0.974516355	0.517053995	normal	0.593446756	0.402023503	normal	[E]	Amino acid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; 	"K01583|0|hsa:113451|AZIN2, ADC, AZI2, AZIB1, ODC-p, ODC1L, ODCp; antizyme inhibitor 2; K01583 arginine decarboxylase [EC:4.1.1.19] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	"Pyridoxal-dependent decarboxylase, pyridoxal binding domain;; Pyridoxal-dependent decarboxylase, C-terminal sheet domain"	Antizyme inhibitor 2 GN=AZIN2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: arginine decarboxylase isoform X1 [Vicugna pacos]
ENSG00000142937(RPS8)	--	743.9997	9938	669.222	9108	643.4646	8868	758.4536	10540	764.2507	10253	725.1494	9960	0.996113093	0.054007049	normal	0.993678616	0.149389957	normal	0.993250286	0.159219896	normal	0.618063102	0.118273713	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02995|8.26714e-150|umr:103670787|RPS8; ribosomal protein S8; K02995 small subunit ribosomal protein S8e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S8e	40S ribosomal protein S8 GN=RPS8 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S8 [Equus caballus] 
ENSG00000142945(KIF2C)	--	18.31857489	1068	15.921265	910	17.8910535	1094	16.46302453	1007	17.10979438	1036	16.5767625	1011	0.974525392	-0.115509055	normal	0.965890915	0.165401244	normal	0.97409801	-0.121945777	normal	0.921081951	-0.029421611	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10393|0|pps:100971992|KIF2C; kinesin family member 2C; K10393 kinesin family member 2/24 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIF2C GN=KIF2C OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF2C isoform X1 [Equus przewalskii]
ENSG00000142949(PTPRF)	--	63.0629615	10244	63.996124	10576	60.70294296	10177	129.2347007	21087	133.7275142	21752	103.825319	16978	1.98E-07	1.01063462	up	2.72E-07	1.018823712	up	0.00436989	0.729977854	normal	1.85E-09	0.926633389	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K05695|0|hsa:5792|PTPRF, BNAH2, LAR; protein tyrosine phosphatase, receptor type, F (EC:3.1.3.48); K05695 receptor-type tyrosine-protein phosphatase F [EC:3.1.3.48] (A)"	Cell adhesion molecules (CAMs) (ko04514);; Adherens junction (ko04520);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Interferon-alpha/beta receptor, fibronectin type III;; Immunoglobulin domain;; Dual specificity phosphatase, catalytic domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Tyrosine phosphatase family"	Receptor-type tyrosine-protein phosphatase F (Precursor) GN=PTPRF OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase F isoform 1 [Trichechus manatus latirostris]
ENSG00000142959(BEST4)	--	0.0290807	1	0.0285602	1	0	0	0.0286902	1	0.0280299	0	0.17122	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13881|0|ptr:469186|BEST4, VMD2L2; bestrophin 4; K13881 bestrophin-4 (A)"	--	[R]	General function prediction only	"Bestrophin, RFP-TM, chloride channel"	Bestrophin-4 GN=BEST4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: bestrophin-4 isoform X1 [Erinaceus europaeus] 
ENSG00000143001(TMEM61)	--	0.30798	5	0.298624	5	0.173174	2	0.0603497	1	0.119095	1	0.480029	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMEM61 protein family	Transmembrane protein 61 GN=TMEM61 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 61 [Trichechus manatus latirostris]
ENSG00000143013(LMO4)	--	11.66325021	403	8.360240237	320	7.124830134	275	15.50687018	626	17.80291023	662	14.98197015	585	0.098288743	0.602693553	normal	5.26E-06	1.023897553	up	1.34E-06	1.07655966	up	4.11E-07	0.886486076	normal	--	--	--	--	--	[R]	General function prediction only	LIM domain	LIM domain transcription factor LMO4 GN=LMO4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	LIM domain transcription factor LMO4 [Myotis brandtii]
ENSG00000143028(SYPL2)	--	0.0502716	3	0	0	0.0163695	0	0.0335857	2	0.016306	0	0.0497654	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Membrane-associating domain	Synaptophysin-like protein 2 GN=SYPL2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: synaptophysin-like protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000143033(MTF2)	--	6.356272567	382	7.653634235	463	7.29060005	437	7.004746818	438	6.6700795	415	6.086794515	380	0.955090545	0.165902484	normal	0.95201098	-0.178710484	normal	0.943573985	-0.209148457	normal	0.817254412	-0.077811081	normal	--	--	--	K11485|0|pon:100173244|MTF2; metal response element binding transcription factor 2; K11485 polycomb-like protein 2 (A)	--	[R]	General function prediction only	Polycomb-like MTF2 factor 2;; PHD-finger	Metal-response element-binding transcription factor 2 GN=MTF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: metal-response element-binding transcription factor 2 isoform 1 [Orcinus orca] 
ENSG00000143036(SLC44A3)	--	2.25457601	69	1.634668305	55	2.495892939	49	2.81482509	84	2.519157605	77	2.694596297	78	0.961512578	0.247950706	normal	0.919364838	0.453420348	normal	0.79137612	0.646454966	normal	0.38177421	0.444446436	normal	--	--	--	"K15282|0|hsa:126969|SLC44A3, CTL3; solute carrier family 44, member 3; K15282 solute carrier family 44 (choline transporter-like protein), member 3 (A)"	Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Plasma-membrane choline transporter	Choline transporter-like protein 3 GN=SLC44A3 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: choline transporter-like protein 3 isoform X1 [Lipotes vexillifer]
ENSG00000143061(IGSF3)	--	14.74522533	2153	12.64697781	1854	16.22246595	2106	18.63956281	2717	20.30051931	2944	15.34870122	2243	0.930372136	0.304640104	normal	0.02575497	0.64528869	normal	0.985855253	0.082575278	normal	0.049446839	0.349176497	normal	--	--	--	"K06522|0|ptr:469428|IGSF3; immunoglobulin superfamily, member 3; K06522 immunoglobulin superfamily, member 2/3 (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Domain of unknown function (DUF3821)	Immunoglobulin superfamily member 3 (Precursor) GN=IGSF3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 3 isoform X1 [Galeopterus variegatus]
ENSG00000143067(ZNF697)	--	1.173678	96	1.032559451	91	1.226271	106	1.578411221	138	1.997925	171	1.6576227	144	0.80957331	0.486208864	normal	0.033672936	0.877824692	normal	0.859066196	0.428449385	normal	0.077603223	0.607885903	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Double zinc ribbon"	Zinc finger protein 697 GN=ZNF697 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 697 [Sus scrofa]
ENSG00000143079(CTTNBP2NL)	--	4.998237	491	5.00041	555	4.780729485	493	6.8197	683	6.93116428	715	8.412971668	840	0.585697245	0.444147272	normal	0.842622141	0.343203068	normal	0.002501311	0.758706653	normal	0.002721168	0.519513302	normal	--	--	--	--	--	[S]	Function unknown	Cortactin-binding protein-2	CTTNBP2 N-terminal-like protein GN=CTTNBP2NL OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: CTTNBP2 N-terminal-like protein [Tupaia chinensis]
ENSG00000143093(STRIP1)	--	7.1884981	603	6.401981003	594	6.953720375	618	7.9754706	623	7.2873103	679	7.945279112	696	0.973778612	0.016201286	normal	0.958106203	0.17111439	normal	0.960950413	0.162813401	normal	0.649305813	0.117812716	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF3402);; N1221-like protein	Striatin-interacting protein 1 GN=STRIP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: striatin-interacting protein 1 [Ceratotherium simum simum]
ENSG00000143106(PSMA5)	--	37.97666201	1278	36.27835638	1222	34.57249088	1221	44.2116517	1480	39.89904011	1337	34.71669221	1145	0.968936629	0.180675106	normal	0.977655097	0.10820058	normal	0.977713528	-0.100877994	normal	0.782360903	0.06855552	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: endopeptidase activity (GO:0004175);; Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Cellular Component: proteasome core complex, alpha-subunit complex (GO:0019773);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; "	"K02729|4.00638e-178|umr:103674995|PSMA5; proteasome (prosome, macropain) subunit, alpha type, 5; K02729 20S proteasome subunit alpha 5 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome subunit A N-terminal signature	Proteasome subunit alpha type-5 GN=PSMA5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit alpha type-5 [Oryctolagus cuniculus] 
ENSG00000143107(FNDC7)	--	0	0	0	0	0.038289671	0	0	0	0.01512431	0	0.038411317	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Fibronectin type III domain	Fibronectin type III domain-containing protein 7 (Precursor) GN=FNDC7 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: fibronectin type III domain-containing protein 7 [Canis lupus familiaris]
ENSG00000143110(C1orf162)	--	0.250324318	3	0.933523207	11	0	0	0	0	0.080629179	0	0.0808608	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein C1orf162 GN=C1orf162 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein C1orf162 homolog [Camelus ferus]
ENSG00000143119(CD53)	--	0	0	0	0	0	0	0.0847807	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06489|4.6793e-137|ptr:745007|CD53; CD53 molecule; K06489 CD53 antigen (A)	--	[R]	General function prediction only	Tetraspanin family	Leukocyte surface antigen CD53 GN=CD53 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: leukocyte surface antigen CD53 [Lipotes vexillifer]
ENSG00000143126(CELSR2)	--	6.681627	1518	6.189594	1425	5.98778934	1398	5.25985144	1186	6.083573	1374	7.271065	1659	0.769326667	-0.386456209	normal	0.981119007	-0.073926569	normal	0.954167702	0.238421058	normal	0.841362315	-0.06137815	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04601|0|hsa:1952|CELSR2, CDHF10, EGFL2, Flamingo1, MEGF3; cadherin, EGF LAG seven-pass G-type receptor 2; K04601 cadherin EGF LAG seven-pass G-type receptor 2 (A)"	--	[T]	Signal transduction mechanisms	Cadherin domain;; Domain of unknown function (DUF3497);; Laminin G domain;; 7 transmembrane receptor (Secretin family);; Laminin G domain;; Latrophilin/CL-1-like GPS domain;; EGF-like domain;; Laminin EGF-like (Domains III and V);; Cadherin prodomain like;; Cadherin-like	Cadherin EGF LAG seven-pass G-type receptor 2 (Precursor) GN=CELSR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cadherin EGF LAG seven-pass G-type receptor 2 isoformX1 [Canis lupus familiaris]
ENSG00000143127(ITGA10)	--	0.391007065	41	0.296388825	29	0.357305532	35	0.144880229	15	0.179130304	18	0.321121165	31	0.228378198	-1.391892193	normal	0.958149283	-0.665072762	normal	0.981911093	-0.175323887	normal	0.254723633	-0.733184765	normal	--	--	--	"K06586|0|hsa:8515|ITGA10, PRO827; integrin, alpha 10; K06586 integrin alpha 10 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; von Willebrand factor type A domain	Integrin alpha-10 (Precursor) GN=ITGA10 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: integrin alpha-10 [Galeopterus variegatus]
ENSG00000143147(GPR161)	--	7.770467911	1061	7.019635631	904	6.717521062	895	7.464439104	909	7.313285056	863	4.75121393	632	0.936050375	-0.253507609	normal	0.974428288	-0.088237674	normal	0.312234801	-0.509225306	normal	0.2574678	-0.272891616	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08439|0|hsa:23432|GPR161, RE2; G protein-coupled receptor 161; K08439 G protein-coupled receptor 161 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 161 GN=GPR161 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 161 isoform X2 [Equus caballus]
ENSG00000143149(ALDH9A1)	--	21.74808	984	21.53638	981	23.18685	1057	32.87668	1462	29.89192	1333	26.62366	1185	0.187043231	0.539685481	normal	0.67395976	0.420367305	normal	0.970200747	0.156408789	normal	0.019062175	0.375578637	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00149|0|hsa:223|ALDH9A1, ALDH4, ALDH7, ALDH9, E3, TMABADH; aldehyde dehydrogenase 9 family, member A1 (EC:1.2.1.3 1.2.1.19 1.2.1.47); K00149 aldehyde dehydrogenase family 9 member A1 [EC:1.2.1.47 1.2.1.3] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Ascorbate and aldarate metabolism (ko00053);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Lysine degradation (ko00310);; Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Glycerolipid metabolism (ko00561);; Pyruvate metabolism (ko00620)"	[C]	Energy production and conversion	Aldehyde dehydrogenase family	4-trimethylaminobutyraldehyde dehydrogenase GN=ALDH9A1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: 4-trimethylaminobutyraldehyde dehydrogenase [Bos mutus] 
ENSG00000143153(ATP1B1)	--	126.9662	4124	135.3704	4314	130.13068	4046	173.690763	5751	205.757048	6626	234.315836	7562	0.693340145	0.448794085	normal	0.105137164	0.597515251	normal	1.17E-05	0.893731813	normal	0.000130107	0.655074295	normal	--	--	Cellular Component: sodium:potassium-exchanging ATPase complex (GO:0005890);; Biological Process: potassium ion transport (GO:0006813);; Biological Process: sodium ion transport (GO:0006814);; 	"K01540|0|hsa:481|ATP1B1, ATP1B; ATPase, Na+/K+ transporting, beta 1 polypeptide; K01540 sodium/potassium-transporting ATPase subunit beta (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Insulin secretion (ko04911);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Proximal tubule bicarbonate reclamation (ko04964);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Carbohydrate digestion and absorption (ko04973);; Protein digestion and absorption (ko04974);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Sodium / potassium ATPase beta chain	Sodium/potassium-transporting ATPase subunit beta-1 GN=ATP1B1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium-transporting ATPase subunit beta-1 isoform 1 [Ceratotherium simum simum] 
ENSG00000143155(TIPRL)	--	20.02627107	797	18.09739508	699	17.16703006	698	21.46665363	882	21.854998	904	19.94249708	832	0.97165442	0.115155592	normal	0.836567784	0.348938322	normal	0.935787216	0.24457911	normal	0.234630632	0.233474507	normal	--	--	--	K17607|0|pps:100976513|TIPRL; TOR signaling pathway regulator; K17607 type 2A phosphatase activator TIP41 (A)	--	[S]	Function unknown	TIP41-like family	TIP41-like protein GN=TIPRL OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: TIP41-like protein [Oryctolagus cuniculus]
ENSG00000143156(NME7)	--	13.8235	348	12.88411	330	16.19079	404	17.77001	452	18.43936	456	13.9417	349	0.844189002	0.34506329	normal	0.643861829	0.443405868	normal	0.940038278	-0.218538705	normal	0.474005542	0.194747264	normal	[F]	Nucleotide transport and metabolism	--	K00940|0|pps:100980228|NME7; NME/NM23 family member 7; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Nucleoside diphosphate kinase	Nucleoside diphosphate kinase 7 GN=NME7 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: nucleoside diphosphate kinase 7 [Loxodonta africana]
ENSG00000143157(POGK)	--	17.388246	1786	20.83795578	1953	20.69120503	1893	19.4619	1964	21.175415	1895	22.8157386	2017	0.9828945	0.106143493	normal	0.985021252	-0.064869662	normal	0.984747591	0.083180845	normal	0.884080262	0.040064637	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; Brinker DNA-binding domain;; KRAB box;; Tc5 transposase DNA-binding domain	Pogo transposable element with KRAB domain GN=POGK OS=Homo sapiens (Human) PE=1 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: pogo transposable element with KRAB domain [Physeter catodon]
ENSG00000143158(MPC2)	--	33.397501	697	31.701905	692	35.456208	768	32.077561	726	34.31692	740	35.732262	755	0.975254962	0.027918329	normal	0.972674107	0.075167807	normal	0.976020831	-0.032855856	normal	0.955437588	0.021302411	normal	--	--	Cellular Component: mitochondrial inner membrane (GO:0005743);; Biological Process: mitochondrial pyruvate transport (GO:0006850);; 	--	--	[S]	Function unknown	Uncharacterised protein family (UPF0041)	Mitochondrial pyruvate carrier 2 GN=MPC2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial pyruvate carrier 2 [Oryctolagus cuniculus]
ENSG00000143162(CREG1)	--	63.0986	1855	71.2975	2100	61.4146	1793	71.8061	2130	65.6578	1925	99.0076	2929	0.977080232	0.168471689	normal	0.979817746	-0.146846943	normal	0.005035463	0.699275275	normal	0.475744516	0.260528943	normal	--	--	--	--	--	[K]	Transcription	Pyridoxamine 5'-phosphate oxidase	Protein CREG1 (Precursor) GN=CREG1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein CREG1 [Myotis davidii]
ENSG00000143164(DCAF6)	--	19.05988537	1273	19.18575579	1287	19.93490332	1318	17.03475726	1141	18.00799	1199	19.89654706	1329	0.964840169	-0.188525386	normal	0.97579747	-0.123456614	normal	0.982749429	0.00369507	normal	0.657499515	-0.100605157	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11795|0|mcc:698686|DCAF6, IQWD1; DDB1 and CUL4 associated factor 6; K11795 nuclear receptor interaction protein (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 6 GN=DCAF6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 6 isoform 1 [Trichechus manatus latirostris]
ENSG00000143167(GPA33)	--	0	0	0.020028593	1	0.019747687	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06790|7.82049e-178|hsa:10223|GPA33, A33; glycoprotein A33 (transmembrane); K06790 cell surface A33 antigen (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Wnt and FGF inhibitory regulator;; Alphaherpesvirus glycoprotein E	Cell surface A33 antigen (Precursor) GN=GPA33 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cell surface A33 antigen [Galeopterus variegatus]
ENSG00000143178(TBX19)	--	0.471531172	23	0.59250341	23	0.604820893	20	0.97344414	45	0.611694762	24	0.56432916	26	0.793761418	0.894076063	normal	0.986510818	0.037556569	normal	0.982927792	0.347143028	normal	0.501549978	0.502017436	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10184|0|pps:100977737|TBX19; T-box 19; K10184 T-box protein 19 (A)	--	[K]	Transcription	T-box	T-box transcription factor TBX19 GN=TBX19 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: T-box transcription factor TBX19 [Galeopterus variegatus]
ENSG00000143179(UCK2)	--	44.979373	2006	46.453749	2211	51.445262	2294	43.22322	1960	41.270071	2003	37.735722	1863	0.985688976	-0.064250428	normal	0.97836061	-0.163845359	normal	0.921094491	-0.308303198	normal	0.334017149	-0.18155404	normal	[F]	Nucleotide transport and metabolism	Molecular Function: dephospho-CoA kinase activity (GO:0004140);; Molecular Function: ATP binding (GO:0005524);; Biological Process: metabolic process (GO:0008152);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; Molecular Function: kinase activity (GO:0016301);; 	K00876|0|ptr:748077|UCK2; uridine-cytidine kinase 2; K00876 uridine kinase [EC:2.7.1.48] (A)	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Phosphoribulokinase / Uridine kinase family;; AAA domain;; Dephospho-CoA kinase	Uridine-cytidine kinase 2 GN=UCK2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: uridine-cytidine kinase 2 [Ochotona princeps]
ENSG00000143183(TMCO1)	--	47.90794439	1188	52.17275576	1301	46.68446063	1062	69.33615038	1698	66.30671948	1658	61.97357554	1492	0.403745921	0.483943398	normal	0.888334224	0.328057972	normal	0.411557301	0.481591056	normal	0.00492586	0.427313689	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Integral membrane protein DUF106	Transmembrane and coiled-coil domain-containing protein 1 GN=TMCO1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane and coiled-coil domain-containing protein 1 [Oryctolagus cuniculus]
ENSG00000143190(POU2F1)	--	4.046885511	930	3.922925228	897	4.01238439	896	3.777615758	866	4.138122629	945	2.895574972	667	0.970310725	-0.133467378	normal	0.976989442	0.053691592	normal	0.61012271	-0.43325269	normal	0.484059674	-0.157860958	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09364|0|pps:100971611|POU2F1; POU class 2 homeobox 1; K09364 POU domain transcription factor, class 2 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 2, transcription factor 1 GN=POU2F1 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: POU domain, class 2, transcription factor 1 isoform 2 [Orcinus orca] "
ENSG00000143194(MAEL)	--	0	0	0.042860509	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of gene silencing by miRNA (GO:0060964);; 	K18411|0|ggo:101131399|MAEL; protein maelstrom homolog isoform 1; K18411 protein maelstrom (A)	--	--	--	piRNA pathway germ-plasm component;; HMG-box domain;; HMG (high mobility group) box	Protein maelstrom homolog GN=MAEL OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein maelstrom homolog isoform X1 [Leptonychotes weddellii]
ENSG00000143195(ILDR2)	--	0	0	0.048194842	2	0.005154257	0	0.015416958	3	0.068096702	3	0.020540981	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lipolysis stimulated receptor (LSR)	Immunoglobulin-like domain-containing receptor 2 (Precursor) GN=ILDR2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: immunoglobulin-like domain-containing receptor 2 [Orcinus orca]
ENSG00000143198(MGST3)	--	109.3100695	1264	95.17827451	1142	105.5952206	1212	132.8307424	1517	119.8613107	1382	141.5315306	1661	0.954259566	0.232134522	normal	0.942863984	0.253462909	normal	0.571254306	0.445893782	normal	0.057322496	0.312913111	normal	--	--	--	"K00799|6.15498e-107|hsa:4259|MGST3, GST-III; microsomal glutathione S-transferase 3 (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	--	--	MAPEG family	Microsomal glutathione S-transferase 3 GN=MGST3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: microsomal glutathione S-transferase 3 [Chrysochloris asiatica]
ENSG00000143199(ADCY10)	--	0.020557357	2	0.157089324	3	0	0	0	0	0.009951497	0	0.134201	1	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	K11265|0|pps:100974597|ADCY10; adenylate cyclase 10 (soluble); K11265 adenylate cyclase 10 [EC:4.6.1.1] (A)	Purine metabolism (ko00230);; cAMP signaling pathway (ko04024);; Circadian entrainment (ko04713)	--	--	Adenylate and Guanylate cyclase catalytic domain	Adenylate cyclase type 10 GN=ADCY10 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: adenylate cyclase type 10 [Leptonychotes weddellii]
ENSG00000143207(RFWD2)	--	15.01427617	581	14.5804449	614	15.77720488	626	16.03312105	638	14.37839844	625	17.35207421	709	0.968790078	0.103923688	normal	0.973403006	0.00418077	normal	0.959402524	0.170943263	normal	0.731192655	0.09410996	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K10143|0|pon:100447738|RFWD2; ring finger and WD repeat domain 2, E3 ubiquitin protein ligase; K10143 E3 ubiquitin-protein ligase RFWD2 [EC:6.3.2.19] (A)"	p53 signaling pathway (ko04115);; Ubiquitin mediated proteolysis (ko04120)	--	--	"WD domain, G-beta repeat;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain"	E3 ubiquitin-protein ligase RFWD2 GN=RFWD2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RFWD2 [Camelus dromedarius]
ENSG00000143217(NECTIN4)	--	0.300140735	19	0.443351603	29	0.460739	30	0.549910832	35	0.576533	37	0.446627	29	0.917820304	0.802118404	normal	0.97589956	0.315453581	normal	0.984835451	-0.054411154	normal	0.659045708	0.351486285	normal	--	--	--	K06593|0|pps:100983947|PVRL4; poliovirus receptor-related 4; K06593 poliovirus receptor-related 4 (A)	Adherens junction (ko04520)	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	Processed poliovirus receptor-related protein 4 (Precursor) GN=PVRL4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: nectin-4 isoform X1 [Galeopterus variegatus]
ENSG00000143222(UFC1)	--	34.333645	686	38.454276	769	40.245164	812	42.026077	827	42.236526	818	45.015955	877	0.938383506	0.23835973	normal	0.974437897	0.067561855	normal	0.973156193	0.102621729	normal	0.570921028	0.132937985	normal	--	--	--	K12165|6.77024e-122|ssc:100157692|UFC1; ubiquitin-fold modifier conjugating enzyme 1; K12165 ufm1-conjugating enzyme 1 (A)	--	[S]	Function unknown	Ubiquitin-fold modifier-conjugating enzyme 1	Ubiquitin-fold modifier-conjugating enzyme 1 GN=UFC1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: ubiquitin-fold modifier-conjugating enzyme 1 [Elephantulus edwardii] 
ENSG00000143224(PPOX)	--	7.122931034	179	5.293594	144	7.873592	191	7.041085	175	6.951601	176	6.892631391	182	0.965860256	-0.062890946	normal	0.933705799	0.265553955	normal	0.964924357	-0.077298577	normal	0.960928484	0.031647035	normal	[H]	Coenzyme transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00231|0|ptr:457450|PPOX; protoporphyrinogen oxidase; K00231 oxygen-dependent protoporphyrinogen oxidase [EC:1.3.3.4] (A)	Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	Flavin containing amine oxidoreductase;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase	Protoporphyrinogen oxidase GN=PPOX OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: protoporphyrinogen oxidase [Elephantulus edwardii]
ENSG00000143226(FCGR2A)	--	0	0	0	0	0	0	0.044730086	2	0.043351195	1	0.022077	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06472|0|hsa:2212|FCGR2A, CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2; Fc fragment of IgG, low affinity IIa, receptor (CD32); K06472 low affinity immunoglobulin gamma Fc region receptor II-a (A)"	Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Platelet activation (ko04611);; Fc gamma R-mediated phagocytosis (ko04666);; Leishmaniasis (ko05140);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Systemic lupus erythematosus (ko05322)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	Low affinity immunoglobulin gamma Fc region receptor II-a (Precursor) GN=FCGR2A OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: low affinity immunoglobulin gamma Fc region receptor II-b isoform 3 [Ceratotherium simum simum]
ENSG00000143228(NUF2)	--	16.15032552	641	15.28286228	593	15.78899378	612	13.14881721	525	11.31923571	441	13.362146	528	0.872656693	-0.317995294	normal	0.598503467	-0.447351805	normal	0.942155355	-0.220697458	normal	0.106150452	-0.326472186	normal	--	--	"Biological Process: mitotic cell cycle (GO:0000278);; Cellular Component: chromosome, centromeric region (GO:0000775);; "	"K11548|0|ptr:457472|NUF2, CDCA1; NUF2, NDC80 kinetochore complex component; K11548 kinetochore protein Nuf2 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Nuf2 family	Kinetochore protein Nuf2 GN=NUF2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: kinetochore protein Nuf2 isoform X1 [Physeter catodon] 
ENSG00000143248(RGS5)	--	1.087035825	28	1.464531686	29	3.825694001	39	0.455051709	10	0.786924533	16	1.13901935	13	0.644236297	-1.384273292	normal	0.933166163	-0.820993347	normal	0.18311114	-1.488789265	normal	0.030348921	-1.319286941	normal	--	--	--	K16449|1.55964e-99|pps:100989294|RGS5; regulator of G-protein signaling 5; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 5 GN=RGS5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"Regulator of G-protein signaling 5, partial [Bos mutus]"
ENSG00000143252(SDHC)	--	105.0224894	2377	128.5845649	2536	119.1534166	2577	126.5031288	2762	111.844917	2744	114.1690306	2850	0.978207066	0.18562777	normal	0.986959208	0.092246288	normal	0.98466333	0.136901517	normal	0.50586514	0.13682067	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; "	"K00236|3.19218e-111|nle:100607083|SDHC; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; K00236 succinate dehydrogenase (ubiquinone) cytochrome b560 subunit (A)"	Citrate cycle (TCA cycle) (ko00020);; Oxidative phosphorylation (ko00190);; Carbon metabolism (ko01200);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[G]	Carbohydrate transport and metabolism	Succinate dehydrogenase/Fumarate reductase transmembrane subunit	"Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (Precursor) GN=SDHC OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: succinate dehydrogenase cytochrome b560 subunit, mitochondrial [Oryctolagus cuniculus]"
ENSG00000143256(PFDN2)	--	71.371	759	59.3951	674	64.6402	737	62.2652	705	68.4244	726	53.5631	584	0.966913501	-0.137020995	normal	0.971624542	0.085609298	normal	0.839709144	-0.343194722	normal	0.600651479	-0.12851453	normal	--	--	Biological Process: protein folding (GO:0006457);; Cellular Component: prefoldin complex (GO:0016272);; Molecular Function: unfolded protein binding (GO:0051082);; 	K09549|3.32885e-79|ptr:457446|PFDN2; prefoldin subunit 2; K09549 prefoldin subunit 2 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prefoldin subunit	Prefoldin subunit 2 GN=PFDN2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prefoldin subunit 2 [Bubalus bubalis]
ENSG00000143257(NR1I3)	--	0.3708785	8	0.3395915	6	0.486334	10	0.672325	12	0.2605902	4	0.733303	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08541|0|mcf:102117522|NR1I3; nuclear receptor subfamily 1, group I, member 3; K08541 constitutive androstane receptor (A)"	--	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor subfamily 1 group I member 3 GN=NR1I3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor subfamily 1 group I member 3 isoformX6 [Equus caballus]
ENSG00000143258(USP21)	--	9.4831558	377	8.63021695	370	10.51522191	426	9.80358066	395	9.564242	377	10.07386645	408	0.968821748	0.036311294	normal	0.968321549	0.005590061	normal	0.96789789	-0.070320613	normal	0.981359573	-0.012286666	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11833|0|mcf:101867013|hypothetical protein; K11833 ubiquitin carboxyl-terminal hydrolase 2/21 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 21 GN=USP21 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 21 isoformX1 [Sus scrofa] 
ENSG00000143278(F13B)	--	0	0	0	0	0.0241556	0	0.0238714	1	0.070506	2	0.0720619	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K03906|0|hsa:2165|F13B, FXIIIB; coagulation factor XIII, B polypeptide (EC:2.3.2.13); K03906 coagulation factor XIII B polypeptide (A)"	Complement and coagulation cascades (ko04610)	--	--	Sushi domain (SCR repeat);; Beta-2-glycoprotein-1 fifth domain	Coagulation factor XIII B chain (Precursor) GN=F13B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: coagulation factor XIII B chain [Trichechus manatus latirostris]
ENSG00000143294(PRCC)	--	27.78624483	1164	27.99774374	1153	26.05614694	1105	31.46499177	1315	34.6124897	1429	32.1496388	1364	0.973407386	0.144959387	normal	0.922148379	0.287847162	normal	0.913323785	0.295141639	normal	0.172985525	0.242471804	normal	--	--	--	K13105|0|ptr:457405|PRCC; papillary renal cell carcinoma (translocation-associated); K13105 proline-rich protein PRCC (A)	Transcriptional misregulation in cancer (ko05202)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Mitotic checkpoint regulator, MAD2B-interacting"	Proline-rich protein PRCC GN=PRCC OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: proline-rich protein PRCC [Pantholops hodgsonii]
ENSG00000143303(RRNAD1)	--	13.411484	387	12.331133	367	11.6882569	401	12.119761	384	14.535245	406	16.65858	469	0.968620146	-0.041892551	normal	0.961111988	0.123787998	normal	0.941169767	0.216937033	normal	0.743975553	0.103917768	normal	--	--	--	--	--	[A]	RNA processing and modification	Methyltransferase domain	Protein RRNAD1 GN=RRNAD1 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: protein RRNAD1 [Ceratotherium simum simum]
ENSG00000143314(MRPL24)	--	83.912383	1203	79.550873	1171	82.512148	1209	78.981469	1173	81.76297	1155	68.81776	989	0.979913238	-0.067178998	normal	0.980255832	-0.041221179	normal	0.907346844	-0.297650879	normal	0.539707827	-0.132910266	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02895|1.94084e-156|ptr:457403|MRPL24; mitochondrial ribosomal protein L24; K02895 large subunit ribosomal protein L24 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	KOW motif	"39S ribosomal protein L24, mitochondrial (Precursor) GN=MRPL24 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L24, mitochondrial isoform X2 [Oryctolagus cuniculus]"
ENSG00000143315(PIGM)	--	8.73492	636	7.66851	556	8.94188	603	8.20766	609	7.25596	538	7.79221	593	0.970109188	-0.093186713	normal	0.96989487	-0.068715253	normal	0.973274281	-0.032335561	normal	0.828193378	-0.066170464	normal	--	--	"Biological Process: GPI anchor biosynthetic process (GO:0006506);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: attachment of GPI anchor to protein (GO:0016255);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; Cellular Component: GPI-anchor transamidase complex (GO:0042765);; "	"K05284|0|ptr:746576|PIGM; phosphatidylinositol glycan anchor biosynthesis, class M; K05284 phosphatidylinositol glycan, class M [EC:2.4.1.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[G]	Carbohydrate transport and metabolism	Mannosyltransferase (PIG-M);; GPI transamidase subunit PIG-U	GPI mannosyltransferase 1 GN=PIGM OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: GPI mannosyltransferase 1 [Pteropus alecto] 
ENSG00000143319(ISG20L2)	--	13.88222985	854	12.56935806	745	13.770304	852	18.13756	1138	17.52392135	1061	14.487066	872	0.766133884	0.38276204	normal	0.40898701	0.487852005	normal	0.977651556	0.025139155	normal	0.084918353	0.303529511	normal	[L]	"Replication, recombination and repair"	--	K18329|0|hsa:81875|ISG20L2; interferon stimulated exonuclease gene 20kDa-like 2; K18329 interferon-stimulated 20 kDa exonuclease-like 2 [EC:3.1.-.-] (A)	--	[L]	"Replication, recombination and repair"	Exonuclease	Interferon-stimulated 20 kDa exonuclease-like 2 GN=ISG20L2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: interferon-stimulated 20 kDa exonuclease-like 2 [Galeopterus variegatus]
ENSG00000143320(CRABP2)	--	6.755596939	118	4.850106151	72	2.883123666	52	5.790594004	101	8.649150196	147	2.672104216	47	0.9505654	-0.251716813	normal	0.013870481	0.993427888	normal	0.976583105	-0.149565037	normal	0.82445739	0.262380235	normal	--	--	--	K17289|3.39818e-96|ptr:469838|CRABP2; cellular retinoic acid binding protein 2; K17289 cellular retinoic acid-binding protein 2 (A)	--	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin / cytosolic fatty-acid binding protein family	Cellular retinoic acid-binding protein 2 GN=CRABP2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	"Cellular retinoic acid-binding protein 2, partial [Bos mutus]"
ENSG00000143321(HDGF)	--	146.5720275	7388	143.6324869	7390	158.5967837	8052	196.1841466	9837	181.9732769	9054	186.6270901	9282	0.914721734	0.382133202	normal	0.979604687	0.271504116	normal	0.990442764	0.196762637	normal	0.122570504	0.282146253	normal	--	--	--	"K16641|1.66002e-143|hsa:3068|HDGF, HMG1L2; hepatoma-derived growth factor; K16641 hepatoma-derived growth factor (A)"	--	[K]	Transcription	PWWP domain	Hepatoma-derived growth factor GN=HDGF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hepatoma-derived growth factor isoform X1 [Equus caballus]
ENSG00000143322(ABL2)	--	7.54456797	1688	8.003515625	1801	8.889388263	1959	11.32356818	2499	10.6243618	2290	13.39155301	2953	0.211659229	0.534801379	normal	0.90673546	0.324880428	normal	0.087492851	0.583403193	normal	0.004663662	0.486446754	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: non-membrane spanning protein tyrosine kinase activity (GO:0004715);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08887|0|ptr:457552|ABL2; ABL proto-oncogene 2, non-receptor tyrosine kinase; K08887 abelson tyrosine-protein kinase 2 [EC:2.7.10.2] (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Viral myocarditis (ko05416)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; F-actin binding;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Bacterial SH3 domain	Abelson tyrosine-protein kinase 2 GN=ABL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: Abelson tyrosine-protein kinase 2 isoform X1 [Galeopterus variegatus]
ENSG00000143324(XPR1)	--	23.34202824	2065	26.37938618	2200	23.51007331	1912	33.56689402	2932	35.73217516	3119	34.36648115	2967	0.487941378	0.474613373	normal	0.488703134	0.481873989	normal	0.033950697	0.625230866	normal	0.000263906	0.524574852	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	EXS family;; SPX domain	Xenotropic and polytropic retrovirus receptor 1 GN=XPR1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: xenotropic and polytropic retrovirus receptor 1 isoform X1 [Mustela putorius furo]
ENSG00000143333(RGS16)	--	0.0414586	2	0	0	0	0	0.0623093	3	0.0809579	3	0.082632	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16449|7.35916e-131|hsa:6004|RGS16, A28-RGS14, A28-RGS14P, RGS-R; regulator of G-protein signaling 16; K16449 regulator of G-protein signaling (A)"	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 16 GN=RGS16 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 16 isoform X1 [Equus caballus] 
ENSG00000143337(TOR1AIP1)	--	18.23044548	1199	21.8113188	1382	18.67066115	1239	17.60638411	1195	17.45486372	1179	18.37728212	1240	0.981165616	-0.035607599	normal	0.944808816	-0.250323522	normal	0.982022039	-0.007118823	normal	0.658008667	-0.101165013	normal	--	--	--	--	--	--	--	Lamina-associated polypeptide 1C (LAP1C)	Torsin-1A-interacting protein 1 GN=TOR1AIP1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: torsin-1A-interacting protein 1 isoform X4 [Balaenoptera acutorostrata scammoni]
ENSG00000143341(HMCN1)	--	1.068398366	324	0.6663147	256	0.58605729	222	0.311326118	119	0.85577499	257	0.68658263	217	1.50E-09	-1.463912398	down	0.966078059	-0.01570939	normal	0.966356916	-0.040874437	normal	0.354207471	-0.455418545	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K17341|0|hsa:83872|HMCN1, ARMD1, FBLN6, FIBL-6, FIBL6; hemicentin 1; K17341 hemicentin (A)"	--	[RP]	General function prediction only;; Inorganic ion transport and metabolism	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; G2F domain;; Calcium-binding EGF domain;; Thrombospondin type 1 domain;; Complement Clr-like EGF-like;; Immunoglobulin C1-set domain;; Penicillin-Binding Protein C-terminus Family;; CD47 immunoglobulin-like domain;; Natural killer cell receptor 2B4;; Immunoglobulin C2-set domain;; Coagulation Factor Xa inhibitory site;; Alphaherpesvirus glycoprotein I;; von Willebrand factor type A domain;; EGF-like domain;; Alpha-2-macroglobulin family	Hemicentin-1 (Precursor) GN=HMCN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: hemicentin-1 isoform X1 [Equus przewalskii]
ENSG00000143344(RGL1)	--	1.093154488	111	1.252133603	126	1.163762547	121	1.2480022	126	2.5414018	249	2.271681897	225	0.963158976	0.150081153	normal	0.002045534	0.953010253	normal	0.010126606	0.878450266	normal	0.134015471	0.725523849	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: signal transduction (GO:0007165);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17635|0|mcf:102125141|RGL1; ral guanine nucleotide dissociation stimulator-like 1; K17635 ral guanine nucleotide dissociation stimulator-like 1 (A)	Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; Ras association (RalGDS/AF-6) domain	Ral guanine nucleotide dissociation stimulator-like 1 GN=RGL1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: ral guanine nucleotide dissociation stimulator-like 1 isoformX2 [Equus caballus]
ENSG00000143353(LYPLAL1)	--	12.53942	298	13.84252	327	11.40659	266	10.94098	268	12.43916	298	11.42285	274	0.950274921	-0.182916485	normal	0.95511137	-0.15465529	normal	0.966946249	0.034266253	normal	0.768535353	-0.106407863	normal	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	K06999|7.94796e-177|ptr:457743|LYPLAL1; lysophospholipase-like 1; K06999 phospholipase/carboxylesterase (A)	--	[I]	Lipid transport and metabolism	Phospholipase/Carboxylesterase;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; Dienelactone hydrolase family;; alpha/beta hydrolase fold;; Putative esterase	Lysophospholipase-like protein 1 GN=LYPLAL1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: lysophospholipase-like protein 1 [Ceratotherium simum simum]
ENSG00000143355(LHX9)	--	1.16922742	46	0.11254611	10	0.14098276	13	0.094787334	10	0.421991565	29	0.39135407	26	0.001430355	-2.071114255	down	0.61226833	1.38672792	normal	0.933863986	0.915169602	normal	0.971095564	-0.105672701	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K09373|0|ptr:469628|LHX9; LIM homeobox 9; K09373 LIM homeobox protein 2/9 (A)	--	[R]	General function prediction only	LIM domain;; Homeobox domain	LIM/homeobox protein Lhx9 GN=LHX9 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LIM/homeobox protein Lhx9 isoform X1 [Orycteropus afer afer]
ENSG00000143363(PRUNE1)	--	6.151740604	326	6.475124112	330	5.635461999	294	7.035392722	354	7.508384251	352	6.88469904	349	0.964995865	0.087648668	normal	0.965357192	0.071366159	normal	0.932781185	0.23799456	normal	0.688756215	0.129821489	normal	[C]	Energy production and conversion	Cellular Component: cytoplasm (GO:0005737);; Molecular Function: pyrophosphatase activity (GO:0016462);; 	"K01514|0|hsa:58497|PRUNE, DRES-17, DRES17, HTCD37; prune exopolyphosphatase (EC:3.6.1.1); K01514 exopolyphosphatase [EC:3.6.1.11] (A)"	Purine metabolism (ko00230)	[C]	Energy production and conversion	DHHA2 domain;; DHH family	Protein prune homolog GN=PRUNE OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: protein prune homolog [Galeopterus variegatus]
ENSG00000143365(RORC)	--	0	0	0.048973574	2	0.031334499	1	0	0	0.015813088	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08534|0|pon:100172603|RORC, NR1F3; RAR-related orphan receptor C; K08534 RAR-related orphan receptor gamma (A)"	Circadian rhythm (ko04710);; Inflammatory bowel disease (IBD) (ko05321)	[K]	Transcription	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor ROR-gamma GN=RORC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor ROR-gamma isoform X1 [Galeopterus variegatus]
ENSG00000143367(TUFT1)	--	7.39266937	437	8.93575283	523	12.3108329	733	17.53359608	1033	11.60025009	679	10.42136602	616	1.21E-09	1.207460397	up	0.825212831	0.354272778	normal	0.925793148	-0.258591534	normal	0.401697551	0.437358734	normal	--	--	--	--	--	--	--	Putative GRINL1B complex locus protein 2	Tuftelin GN=TUFT1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tuftelin isoform X1 [Tupaia chinensis]
ENSG00000143368(SF3B4)	--	57.48440209	1905	60.36961623	2001	56.11250824	1874	65.09920621	2107	65.72380631	2130	56.90460688	1883	0.98305949	0.114479239	normal	0.985589129	0.06865541	normal	0.986306105	-0.001378286	normal	0.806387137	0.060891151	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12831|1.21357e-157|mze:101470799|splicing factor 3B subunit 4-like; K12831 splicing factor 3B subunit 4 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing factor 3B subunit 4 GN=SF3B4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	myotubularin-related protein 11-like protein [Camelus ferus]
ENSG00000143369(ECM1)	--	1.2684563	53	0.95085392	39	1.020579557	42	1.769464758	72	1.1509315	48	1.509225526	63	0.943232979	0.401162704	normal	0.972162366	0.268727627	normal	0.904500604	0.560100929	normal	0.466278509	0.427721559	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	Extracellular matrix protein 1 (ECM1)	Extracellular matrix protein 1 (Precursor) GN=ECM1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: extracellular matrix protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000143373(ZNF687)	--	12.97913001	1185	10.442271	1040	11.1260289	1103	10.02935458	822	10.080099	958	10.7724081	1057	0.141051385	-0.557635534	normal	0.970610648	-0.13970079	normal	0.978698517	-0.069651295	normal	0.166874004	-0.250692907	normal	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 687 GN=ZNF687 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 687 [Galeopterus variegatus]
ENSG00000143374(TARS2)	--	12.87278435	670	12.24371533	640	13.33160818	706	13.44352232	716	12.96840229	665	13.49788682	702	0.973465423	0.064822425	normal	0.97352608	0.033777578	normal	0.975443988	-0.016453251	normal	0.941666128	0.026034676	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	"K01868|0|ptr:746922|TARS2, TARSL1; threonyl-tRNA synthetase 2, mitochondrial (putative) (EC:6.1.1.3); K01868 threonyl-tRNA synthetase [EC:6.1.1.3] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain;; TGS domain;; Threonyl and Alanyl tRNA synthetase second additional domain"	"Threonine--tRNA ligase, mitochondrial (Precursor) GN=TARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: threonine--tRNA ligase, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000143375(CGN)	--	2.141419	265	1.696335509	218	2.1140871	272	0.6774234	79	1.428541	135	0.48220076	59	7.42E-12	-1.757068009	down	0.135424581	-0.706504949	normal	0	-2.184470515	down	3.64E-08	-1.488814765	down	--	--	Molecular Function: motor activity (GO:0003774);; Cellular Component: myosin complex (GO:0016459);; 	K06102|0|hsa:57530|CGN; cingulin; K06102 cingulin (A)	Tight junction (ko04530)	--	--	Myosin tail	Cingulin GN=CGN OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: cingulin isoform X1 [Tupaia chinensis] 
ENSG00000143376(SNX27)	--	7.1156544	813	7.815805	903	8.829664	970	7.857748815	904	7.46707188	861	8.123025002	943	0.971150807	0.122016421	normal	0.974269761	-0.089984954	normal	0.978192993	-0.048941028	normal	0.982012688	-0.009115799	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17936|0|pps:100988024|SNX27; sorting nexin family member 27; K17936 sorting nexin-27 (A)	--	[RTU]	"General function prediction only;; Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PX domain;; PDZ domain (Also known as DHR or GLGF);; Ras association (RalGDS/AF-6) domain	Sorting nexin-27 GN=SNX27 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	sorting nexin-27 [Bos taurus] 
ENSG00000143379(SETDB1)	--	9.152291	661	9.161111	662	8.540433	622	7.5846289	601	8.843566	665	9.52202257	735	0.95920003	-0.167708506	normal	0.974114577	-0.014869543	normal	0.939785829	0.232018728	normal	0.958786346	0.020268577	normal	[R]	General function prediction only	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; 	"K11421|0|hsa:9869|SETDB1, ESET, H3-K9-HMTase4, KG1T, KMT1E, TDRD21; SET domain, bifurcated 1 (EC:2.1.1.43); K11421 histone-lysine N-methyltransferase SETDB1 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[B]	Chromatin structure and dynamics	SET domain;; Pre-SET motif;; Methyl-CpG binding domain	Histone-lysine N-methyltransferase SETDB1 GN=SETDB1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase SETDB1 isoform X2 [Bos taurus]
ENSG00000143382(ADAMTSL4)	--	1.546105	135	0.762747484	66	0.764305915	62	1.188443	95	1.842701589	159	0.80153	67	0.747540785	-0.530553781	normal	0.000263398	1.228376071	up	0.97422878	0.101225802	normal	0.812924527	0.265268492	normal	--	--	Molecular Function: peptidase activity (GO:0008233);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Thrombospondin type 1 domain;; PLAC (protease and lacunin) domain	ADAMTS-like protein 4 (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ADAMTS-like protein 4 isoform X1 [Equus przewalskii]
ENSG00000143384(MCL1)	--	55.4301621	3291	53.58807584	3235	56.77944101	3378	99.86973878	6038	89.7347999	5334	84.74508454	5066	6.32E-05	0.844417257	normal	0.007448265	0.699768301	normal	0.123059627	0.576174272	normal	5.50E-07	0.709270949	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K02539|1.42884e-177|ptr:457274|MCL1; myeloid cell leukemia 1; K02539 myeloid leukemia cell differntiation protein MCL-1 (A)	PI3K-Akt signaling pathway (ko04151);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	"Apoptosis regulator proteins, Bcl-2 family"	Induced myeloid leukemia cell differentiation protein Mcl-1 GN=MCL1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: induced myeloid leukemia cell differentiation protein Mcl-1 isoform X1 [Galeopterus variegatus]
ENSG00000143387(CTSK)	--	10.08698025	992	9.757783017	938	10.39282107	867	10.23910296	1014	12.76464488	1186	11.18511057	1087	0.97958268	0.000812119	normal	0.88889643	0.316562835	normal	0.882830424	0.317461064	normal	0.268180019	0.211795794	normal	--	--	Molecular Function: cysteine-type endopeptidase activity (GO:0004197);; Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K01371|0|hsa:1513|CTSK, CTS02, CTSO, CTSO1, CTSO2, PKND, PYCD; cathepsin K (EC:3.4.22.38); K01371 cathepsin K [EC:3.4.22.38] (A)"	Lysosome (ko04142);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; Rheumatoid arthritis (ko05323)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin propeptide inhibitor domain (I29);; Peptidase C1-like family	Cathepsin K (Precursor) GN=CTSK OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin K isoform X1 [Equus przewalskii]
ENSG00000143390(RFX5)	--	24.51694136	1410	19.51977165	1317	21.59307288	1342	15.96570955	1091	17.52993603	1120	19.7639416	1267	0.726195535	-0.400378766	normal	0.941261423	-0.254865413	normal	0.979676767	-0.091153855	normal	0.161964824	-0.247176425	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K08061|0|hsa:5993|RFX5; regulatory factor X, 5 (influences HLA class II expression); K08061 regulatory factor X 5 (A)"	Antigen processing and presentation (ko04612);; Tuberculosis (ko05152);; Primary immunodeficiency (ko05340)	[K]	Transcription	RFX5 DNA-binding domain;; RFX DNA-binding domain	DNA-binding protein RFX5 GN=RFX5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-binding protein RFX5 [Ceratotherium simum simum]
ENSG00000143393(PI4KB)	--	14.7051916	1066	13.5317934	1008	14.80935832	1058	15.89840074	1250	14.89593187	1089	15.71503507	1222	0.961426843	0.198623822	normal	0.976521335	0.089951902	normal	0.96108388	0.19934787	normal	0.420002806	0.163927595	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; 	"K00888|0|pon:100456185|PI4KB; phosphatidylinositol 4-kinase, catalytic, beta; K00888 phosphatidylinositol 4-kinase [EC:2.7.1.67] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Phosphatidylinositol 3- and 4-kinase	Phosphatidylinositol 4-kinase beta GN=PI4KB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-kinase beta isoform X1 [Bos mutus] 
ENSG00000143398(PIP5K1A)	--	28.5369875	1651	26.71481055	1559	32.4265433	1697	28.769118	1658	28.44693495	1764	28.17637774	1696	0.984873919	-0.024705435	normal	0.975864948	0.156660145	normal	0.985300176	-0.009133695	normal	0.886355032	0.039760213	normal	[T]	Signal transduction mechanisms	Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; 	"K00889|0|ptr:457288|PIP5K1A; phosphatidylinositol-4-phosphate 5-kinase, type I, alpha (EC:2.7.1.68); K00889 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Phosphatidylinositol-4-phosphate 5-Kinase	Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha GN=PIP5K1A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-phosphate 5-kinase type-1 alpha isoform X3 [Felis catus]
ENSG00000143401(ANP32E)	--	45.42291883	2421	42.30825346	2313	46.51583304	2458	50.59213608	2760	48.18345444	2542	41.97585386	2215	0.982035494	0.158138886	normal	0.984856565	0.114700654	normal	0.980707936	-0.158366967	normal	0.875086984	0.042002882	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K18648|5.81671e-99|pps:100979122|acidic leucine-rich nuclear phosphoprotein 32 family member E; K18648 acidic leucine-rich nuclear phosphoprotein 32 family member E (A)	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine-rich repeat;; Leucine Rich repeat;; Leucine rich repeat;; Leucine Rich Repeat	Acidic leucine-rich nuclear phosphoprotein 32 family member E GN=ANP32E OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: acidic leucine-rich nuclear phosphoprotein 32 family member E isoform X3 [Galeopterus variegatus]
ENSG00000143409(MINDY1)	--	2.940433209	221	2.877569675	206	2.924407205	230	3.239545165	248	3.110389426	213	3.657213067	251	0.959134598	0.134577977	normal	0.965551277	0.026590565	normal	0.961242021	0.117025293	normal	0.821676026	0.094910599	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Molecular Function: Lys48-specific deubiquitinase activity (GO:1990380);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF544)	Protein FAM63A GN=FAM63A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM63A isoform X1 [Galeopterus variegatus] 
ENSG00000143412(ANXA9)	--	0.615543	22	0.524439	19	0.403231	14	0.357125	13	0.545121	19	0.628498	23	0.971576593	-0.723417713	normal	--	--	--	0.973882261	0.652462165	normal	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	"K17090|0|hsa:8416|ANXA9, ANX31; annexin A9; K17090 annexin A9 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A9 GN=ANXA9 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A9 [Galeopterus variegatus]
ENSG00000143416(SELENBP1)	--	4.405090765	148	2.568605242	89	3.356554267	121	4.412225528	146	5.919891183	202	3.678689049	126	0.967253099	-0.049939086	normal	0.000194071	1.147762371	up	0.968379284	0.049518723	normal	0.419100504	0.383705285	normal	--	--	Molecular Function: selenium binding (GO:0008430);; 	K17285|0|ggo:101126573|selenium-binding protein 1-like isoform 1; K17285 selenium-binding protein 1 (A)	--	[P]	Inorganic ion transport and metabolism	"56kDa selenium binding protein (SBP56);; Lactonase, 7-bladed beta-propeller"	Selenium-binding protein 1 GN=SELENBP1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: selenium-binding protein 1 isoform X1 [Panthera tigris altaica]
ENSG00000143418(CERS2)	--	136.776269	4761	120.9687322	4328	120.6227958	4451	132.1482541	4676	128.3010083	4470	152.0497808	5317	0.992654262	-0.056803465	normal	0.992389285	0.025139131	normal	0.976158674	0.248114299	normal	0.763770602	0.074289456	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: DNA binding (GO:0003677);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04710|0|ptr:469482|CERS2, LASS2; ceramide synthase 2; K04710 ceramide synthetase [EC:2.3.1.24] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TLC domain;; Homeobox domain	Ceramide synthase 2 GN=CERS2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ceramide synthase 2 [Oryctolagus cuniculus]
ENSG00000143420(ENSA)	--	81.98064952	2460	75.22991092	2478	83.42062589	2500	82.40014738	2548	68.81839846	2150	97.51578401	2899	0.988742955	0.019862509	normal	0.967768806	-0.226117788	normal	0.975498325	0.205220418	normal	0.980122653	0.009662127	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Putative binding domain;; cAMP-regulated phosphoprotein/endosulfine conserved region	Alpha-endosulfine GN=ENSA OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: alpha-endosulfine isoform 1 [Ceratotherium simum simum]
ENSG00000143434(SEMA6C)	--	1.835230037	120	0.947444163	72	1.263021156	89	1.188807646	77	1.225264395	81	1.002023991	72	0.546448942	-0.66029038	normal	0.968487588	0.145613741	normal	0.949908799	-0.30826513	normal	0.543443874	-0.31030411	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06842|0|hsa:10500|SEMA6C, SEMAY, m-SemaY, m-SemaY2; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C; K06842 semaphorin 6 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-6C (Precursor) GN=SEMA6C OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: semaphorin-6C isoform X2 [Galeopterus variegatus]
ENSG00000143436(MRPL9)	--	27.85266	654	27.7732	654	29.659573	694	34.20741	825	29.41871	694	33.884543	804	0.891091624	0.303634953	normal	0.972620098	0.06407463	normal	0.952267121	0.203555949	normal	0.368937191	0.193309559	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02939|5.4454e-172|ggo:101138144|MRPL9; 39S ribosomal protein L9, mitochondrial; K02939 large subunit ribosomal protein L9 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein L9, N-terminal domain"	"39S ribosomal protein L9, mitochondrial (Precursor) GN=MRPL9 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L9, mitochondrial isoform X3 [Galeopterus variegatus]"
ENSG00000143442(POGZ)	--	12.68713797	1471	12.09067801	1526	11.88367727	1434	13.28149763	1443	12.87504537	1460	18.41149219	1834	0.982652942	-0.058496519	normal	0.981268012	-0.085126893	normal	0.863779165	0.346333434	normal	0.762719635	0.075771004	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	DDE superfamily endonuclease;; Tc5 transposase DNA-binding domain	Pogo transposable element with ZNF domain GN=Nbla00003 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: pogo transposable element with ZNF domain isoform X1 [Galeopterus variegatus] 
ENSG00000143443(C1orf56)	--	5.68346	204	5.13239	184	5.7871	209	3.67993	133	4.70414	169	4.07116	148	0.290485432	-0.641938037	normal	0.958106155	-0.142883249	normal	0.662915712	-0.501860114	normal	0.175796042	-0.428434441	normal	--	--	--	--	--	--	--	"Protein missing in infertile sperm 1, putative"	Protein MENT (Precursor) GN=MENT OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein MENT [Galeopterus variegatus]
ENSG00000143450(OAZ3)	--	1.373865753	18	1.709171	26	2.4931202	28	0.6126303	14	0.54565929	10	0.804513574	16	--	--	--	0.778153408	-1.276332322	normal	0.951124767	-0.760669194	normal	--	--	--	--	--	Molecular Function: ornithine decarboxylase inhibitor activity (GO:0008073);; 	K16614|2.90115e-172|ptr:469486|OAZ3; ornithine decarboxylase antizyme 3; K16614 ornithine decarboxylase antizyme 3 (A)	--	[E]	Amino acid transport and metabolism	Ornithine decarboxylase antizyme	Ornithine decarboxylase antizyme 3 GN=OAZ3 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	ornithine decarboxylase antizyme 3 isoform 1 [Mustela putorius furo]
ENSG00000143452(HORMAD1)	--	15.39559985	805	14.03372724	809	13.77362139	847	16.62850765	983	16.2993364	941	18.51242664	1064	0.931850273	0.256926036	normal	0.956780762	0.196287989	normal	0.878778127	0.320261604	normal	0.162943097	0.259044415	normal	--	--	--	--	--	[B]	Chromatin structure and dynamics	HORMA domain	HORMA domain-containing protein 1 GN=HORMAD1 OS=Homo sapiens (Human) PE=2 SV=1	B	Chromatin structure and dynamics	PREDICTED: HORMA domain-containing protein 1 isoform 1 [Equus caballus] 
ENSG00000143458(GABPB2)	--	1.87314077	183	1.366974582	181	1.59010452	174	1.719109	186	1.391345591	184	1.95261882	216	0.967121486	-0.007312396	normal	0.965928903	0.002270695	normal	0.913238142	0.301297968	normal	0.823286826	0.102458333	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K09454|0|hsa:126626|GABPB2; GA binding protein transcription factor, beta subunit 2; K09454 GA-binding protein transcription factor, beta (A)"	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	GA-binding protein subunit beta-2 GN=GABPB2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: GA-binding protein subunit beta-2 [Orycteropus afer afer]
ENSG00000143469(SYT14)	--	0.092611976	11	0.432998146	34	0.079516221	14	0.184689336	23	0.194607948	23	0.229037367	33	0.948212671	0.940819295	normal	0.96078137	-0.555122597	normal	0.743129996	1.145993024	normal	0.687336207	0.399999987	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-14 GN=SYT14 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-14 isoform X1 [Tupaia chinensis]
ENSG00000143473(KCNH1)	--	0.921523061	146	1.655441973	216	1.724914785	232	4.622202444	640	4.508931741	658	6.047778665	918	0	2.089824791	up	4.14E-14	1.578975118	up	0	1.969112607	up	3.12E-08	1.879693323	up	[T]	Signal transduction mechanisms	"Molecular Function: ion channel activity (GO:0005216);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; "	"K04904|0|mcf:102141217|KCNH1; potassium voltage-gated channel, subfamily H (eag-related), member 1; K04904 potassium voltage-gated channel Eag-related subfamily H member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; PAS domain;; Cyclic nucleotide-binding domain;; Ion channel;; PAS fold	Potassium voltage-gated channel subfamily H member 1 GN=KCNH1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily H member 1 [Equus caballus]
ENSG00000143476(DTL)	--	13.402223	1058	14.02730972	1094	16.14587083	1245	14.82674827	1170	14.44067317	1137	12.43656483	983	0.975611816	0.114178927	normal	0.979950713	0.034146657	normal	0.842159117	-0.348696031	normal	0.792609278	-0.0675914	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11790|0|ptr:469674|DTL; denticleless E3 ubiquitin protein ligase homolog (Drosophila); K11790 denticleless (A)	--	[S]	Function unknown	"WD domain, G-beta repeat"	Denticleless protein homolog GN=DTL OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: denticleless protein homolog isoform X1 [Oryctolagus cuniculus]
ENSG00000143479(DYRK3)	--	4.50748862	381	4.684649842	451	5.34819736	421	5.773896226	505	5.46066198	472	6.795070527	555	0.793015753	0.374345253	normal	0.969364738	0.044088356	normal	0.758437193	0.389154905	normal	0.237880712	0.269074184	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K18669|0|ggo:101128537|DYRK3; dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform 1; K18669 dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:2.7.12.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Dual specificity tyrosine-phosphorylation-regulated kinase 3 GN=DYRK3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 3 isoform X1 [Leptonychotes weddellii]
ENSG00000143486(EIF2D)	--	17.1883881	711	17.49136791	737	17.09947414	715	18.62621543	780	18.60870936	771	20.71652727	867	0.97142802	0.102580622	normal	0.974936885	0.043552307	normal	0.921748985	0.269279341	normal	0.549822625	0.139863469	normal	--	--	Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	"K15027|0|pon:100172724|EIF2D, LGTN; eukaryotic translation initiation factor 2D; K15027 translation initiation factor 2D (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Translation initiation factor SUI1	Eukaryotic translation initiation factor 2D GN=EIF2D OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 2D isoform X1 [Felis catus]
ENSG00000143493(INTS7)	--	10.3167698	622	13.44990909	689	11.56930303	638	13.65589441	772	15.76524927	885	16.44238568	955	0.911033174	0.280231706	normal	0.851433527	0.33908872	normal	0.120146907	0.572536338	normal	0.020562444	0.401820751	normal	--	--	--	K13144|0|pps:100974631|INTS7; integrator complex subunit 7; K13144 integrator complex subunit 7 (A)	--	[S]	Function unknown	HEAT repeats	Integrator complex subunit 7 GN=INTS7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: integrator complex subunit 7 isoform 1 [Ceratotherium simum simum]
ENSG00000143494(VASH2)	--	0.74752381	51	0.861682483	55	0.880535355	55	1.392863108	87	1.958635737	95	1.223839451	84	0.635782018	0.722838625	normal	0.512099745	0.75117603	normal	0.824928278	0.589459961	normal	0.109006295	0.703181981	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of angiogenesis (GO:0045765);; 	--	--	--	--	Vasohibin	Vasohibin-2 GN=VASH2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: vasohibin-2 isoform X1 [Felis catus] 
ENSG00000143498(TAF1A)	--	5.52503408	271	6.0226422	317	6.357002305	310	5.531779313	264	6.237474181	304	6.964314126	347	0.965373265	-0.068195434	normal	0.964084369	-0.081441286	normal	0.956504895	0.153667124	normal	0.995489851	0.006763953	normal	--	--	--	"K15212|0|hsa:9015|TAF1A, MGC:17061, RAFI48, SL1, TAFI48; TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa; K15212 TATA box-binding protein-associated factor RNA polymerase I subunit A (A)"	--	--	--	TAF RNA Polymerase I subunit A	TATA box-binding protein-associated factor RNA polymerase I subunit A GN=TAF1A OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TATA box-binding protein-associated factor RNA polymerase I subunit A [Tupaia chinensis]
ENSG00000143499(SMYD2)	--	14.0131316	454	15.89002021	520	13.25978	432	17.84842032	585	14.80117073	478	15.675794	507	0.853291614	0.333914363	normal	0.960690679	-0.142495164	normal	0.939765436	0.221945098	normal	0.609464101	0.137223667	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11426|0|hsa:56950|SMYD2, HSKM-B, KMT3C, ZMYND14; SET and MYND domain containing 2 (EC:2.1.1.43); K11426 SET and MYND domain-containing protein (A)"	--	[B]	Chromatin structure and dynamics	SET domain;; MYND finger	N-lysine methyltransferase SMYD2 GN=SMYD2 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	N-lysine methyltransferase SMYD2 [Bos taurus] 
ENSG00000143502(SUSD4)	--	0.020516828	1	0.060729019	2	0	0	0.120828469	7	0.176936654	5	0.113614882	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sushi domain (SCR repeat)	Sushi domain-containing protein 4 (Precursor) GN=SUSD4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: sushi domain-containing protein 4 [Bos mutus]
ENSG00000143507(DUSP10)	--	1.806604	78	3.74321	157	1.910786	88	3.712564	172	4.856625	227	5.818961	267	0.001237171	1.095152397	up	0.631589623	0.506423609	normal	9.58E-10	1.576632405	up	0.015277544	1.023482994	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K04459|0|hsa:11221|DUSP10, MKP-5, MKP5; dual specificity phosphatase 10 (EC:3.1.3.16 3.1.3.48); K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 10 GN=DUSP10 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 10 [Oryctolagus cuniculus] 
ENSG00000143512(HHIPL2)	--	4.638906603	228	2.948029665	157	3.035888519	165	2.593438868	121	2.883448	142	1.848858993	97	0.003320837	-0.936047933	normal	0.956902221	-0.16463187	normal	0.138077724	-0.765443196	normal	0.053337099	-0.633280743	normal	--	--	--	--	--	--	--	Glucose / Sorbosone dehydrogenase;; Folate receptor family	HHIP-like protein 2 (Precursor) GN=HHIPL2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: HHIP-like protein 2 [Tupaia chinensis]
ENSG00000143514(TP53BP2)	--	9.320657185	911	9.529211	926	11.03824615	1035	13.18415084	1287	11.45590187	1098	11.83117969	1126	0.471651539	0.466991318	normal	0.950513266	0.224031071	normal	0.975396014	0.113126104	normal	0.1308599	0.268389629	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K16823|0|hsa:7159|TP53BP2, 53BP2, ASPP2, BBP, P53BP2, PPP1R13A; tumor protein p53 binding protein 2; K16823 apoptosis-stimulating of p53 protein 2 (A)"	Hippo signaling pathway (ko04390)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Apoptosis-stimulating of p53 protein 2 GN=TP53BP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: apoptosis-stimulating of p53 protein 2 [Tupaia chinensis]
ENSG00000143515(ATP8B2)	--	12.8595177	1465	14.98323917	1658	12.47140519	1449	14.290726	1570	14.37397489	1569	13.60775598	1541	0.982656846	0.068961762	normal	0.981174856	-0.10093056	normal	0.981953939	0.08043641	normal	0.971576238	0.012287384	normal	[P]	Inorganic ion transport and metabolism	--	K01530|0|ggo:101129100|ATP8B2; probable phospholipid-transporting ATPase ID isoform 1; K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)	--	[R]	General function prediction only	haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase	Phospholipid-transporting ATPase ID GN=ATP8B2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase ID isoform X3 [Equus przewalskii]
ENSG00000143520(FLG2)	--	0.00432436	1	0.0128751	3	0.0170637	3	0.0518998	12	0.0376293	8	0.0299399	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10384|0|hsa:388698|FLG2, IFPS; filaggrin family member 2; K10384 filaggrin (A)"	--	--	--	S-100/ICaBP type calcium binding domain;; Uricase	Filaggrin-2 GN=FLG2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	Filaggrin-2 [Myotis davidii]
ENSG00000143537(ADAM15)	--	32.69035495	1793	32.58031546	1791	31.95715368	1786	45.58315181	2470	46.98260166	2552	30.539567	1687	0.661301231	0.430987468	normal	0.434257322	0.489088817	normal	0.983077566	-0.090484703	normal	0.300955342	0.299020557	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K06836|0|mcf:102134980|ADAM15; ADAM metallopeptidase domain 15; K06836 disintegrin and metalloproteinase domain-containing protein 15 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Disintegrin;; Reprolysin family propeptide;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 15 (Precursor) GN=ADAM15 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 15 isoform 1 [Ceratotherium simum simum]
ENSG00000143543(JTB)	--	95.66854	1772	90.95044	1769	95.579158	1863	113.409687	2192	110.23687	2087	117.78306	2241	0.942856669	0.275821584	normal	0.966546126	0.216899125	normal	0.953243237	0.258032301	normal	0.145146294	0.249791205	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Jumping translocation breakpoint protein (JTB)	Protein JTB (Precursor) GN=JTB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein JTB [Vicugna pacos]
ENSG00000143545(RAB13)	--	78.9738702	1814	62.775751	1482	73.534623	1734	86.54305	2068	83.531302	1909	67.0280162	1565	0.978169369	0.158103988	normal	0.874457739	0.343535503	normal	0.976154637	-0.156089321	normal	0.639479246	0.117989824	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K06109|8.76299e-148|ptr:467033|RAB13; RAB13, member RAS oncogene family; K06109 Ras-related protein Rab-13 (A)"	Tight junction (ko04530)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain;; Signal recognition particle receptor beta subunit	Ras-related protein Rab-13 (Precursor) GN=RAB13 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Rab-13 isoform 1 [Tursiops truncatus] 
ENSG00000143549(TPM3)	--	141.1240466	6310	143.2683467	6620	148.4353742	6734	192.9739452	8578	169.1817119	7539	133.4924074	5928	0.853496872	0.412082699	normal	0.990965825	0.166079826	normal	0.988205733	-0.192163686	normal	0.596275586	0.142690669	normal	--	--	--	K09290|2.0771e-135|myb:102259211|TPM3; tropomyosin 3; K09290 tropomyosin 3 (A)	Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Pathways in cancer (ko05200);; Thyroid cancer (ko05216);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Tropomyosin;; Tropomyosin like;; Laminin Domain II	Tropomyosin alpha-3 chain GN=TPM3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tropomyosin alpha-3 chain isoform X4 [Pantholops hodgsonii]
ENSG00000143553(SNAPIN)	--	30.1604	465	27.7564	431	25.9384	404	28.2485	439	33.2492	513	29.9888	466	0.964523959	-0.113456132	normal	0.93629606	0.2291068	normal	0.947788593	0.196996081	normal	0.728423576	0.104234328	normal	--	--	--	--	--	--	--	Snapin/Pallidin	SNARE-associated protein Snapin GN=SNAPIN OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: SNARE-associated protein Snapin [Tupaia chinensis] 
ENSG00000143554(SLC27A3)	--	13.78285871	1292	14.908036	1400	15.0785145	1520	15.57091492	1470	14.7259547	1390	18.30821726	1781	0.973531355	0.15520471	normal	0.982562109	-0.0317341	normal	0.962393828	0.220122232	normal	0.621581812	0.119489751	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K08772|0|pps:100983082|SLC27A3; solute carrier family 27 (fatty acid transporter), member 3; K08772 solute carrier family 27 (fatty acid transporter), member 3 [EC:6.2.1.-] (A)"	--	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	Long-chain fatty acid transport protein 3 OS=Homo sapiens (Human) PE=2 SV=3	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: long-chain fatty acid transport protein 3 [Loxodonta africana]
ENSG00000143569(UBAP2L)	--	44.97890696	2958	64.63397825	3614	56.53357743	3526	61.03540854	3820	55.96663842	3596	64.59861176	4100	0.914261756	0.3379635	normal	0.991100266	-0.028618038	normal	0.980106589	0.209216706	normal	0.386835714	0.168647913	normal	--	--	--	--	--	--	--	Ubiquitin-associated protein 2	Ubiquitin-associated protein 2-like GN=UBAP2L OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-associated protein 2-like isoform X11 [Myotis brandtii] 
ENSG00000143570(SLC39A1)	--	101.4274743	3447	90.58746326	3302	99.31321857	3518	135.2655806	4645	122.029238	4106	123.8538674	4260	0.825286488	0.399351209	normal	0.954119328	0.292846471	normal	0.965637348	0.26770178	normal	0.048799498	0.320305485	normal	--	--	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14709|2.76469e-175|nle:100598528|SLC39A1; solute carrier family 39 (zinc transporter), member 1; K14709 solute carrier family 39 (zinc transporter), member 1/2/3 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP1 GN=SLC39A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP1 [Condylura cristata]
ENSG00000143575(HAX1)	--	45.89883089	900	45.363176	959	42.9037591	929	40.33124	848	32.35336005	683	50.117241	1076	0.972070619	-0.116488081	normal	0.323415747	-0.510113651	normal	0.957500665	0.203328329	normal	0.74113452	-0.117397088	normal	--	--	--	K16220|2.65633e-160|pps:100974655|HAX1; HCLS1 associated protein X-1; K16220 HCLS1-associated protein X-1 (A)	--	--	--	--	HCLS1-associated protein X-1 GN=HAX1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: HCLS1-associated protein X-1 isoform 2 [Ovis aries]
ENSG00000143578(CREB3L4)	--	5.578067	166	4.621682819	157	4.65078	141	3.906671793	127	4.705504427	128	5.015513075	163	0.851693888	-0.412804018	normal	0.920138815	-0.31270495	normal	0.952898844	0.198899688	normal	0.705814122	-0.171302844	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09048|0|hsa:148327|CREB3L4, AIBZIP, ATCE1, CREB3, CREB4, JAL, hJAL; cAMP responsive element binding protein 3-like 4; K09048 cyclic AMP-responsive element-binding protein 3 (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Processed cyclic AMP-responsive element-binding protein 3-like protein 4 GN=CREB3L4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cyclic AMP-responsive element-binding protein 3-like protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000143590(EFNA3)	--	10.25145502	231	8.629466069	192	9.823547844	206	9.698964934	220	11.20009758	231	9.2336884	202	0.962852197	-0.100536268	normal	0.934449347	0.243608625	normal	0.966506725	-0.036311286	normal	0.954684329	0.032623539	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K05462|1.67295e-141|ptr:740911|EFNA3; ephrin-A3; K05462 ephrin-A (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Ephrin	Ephrin-A3 (Precursor) GN=EFNA3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ephrin-A3 [Oryctolagus cuniculus]
ENSG00000143603(KCNN3)	--	0	0	0.02426777	5	0	0	0	0	0.00415949	0	0.026797231	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calmodulin binding (GO:0005516);; Biological Process: potassium ion transport (GO:0006813);; Molecular Function: calcium-activated potassium channel activity (GO:0015269);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: small conductance calcium-activated potassium channel activity (GO:0016286);; 	"K04944|0|hsa:3782|KCNN3, KCa2.3, SK3, SKCA3, hSK3; potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3; K04944 potassium intermediate/small conductance calcium-activated channel subfamily N member 3 (A)"	Insulin secretion (ko04911)	[P]	Inorganic ion transport and metabolism	Calcium-activated SK potassium channel;; Calmodulin binding domain;; Ion channel	Small conductance calcium-activated potassium channel protein 3 GN=KCNN3 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: small conductance calcium-activated potassium channel protein 3 isoform X2 [Myotis lucifugus]
ENSG00000143612(C1orf43)	--	136.915647	3499	144.21808	3696	139.64227	3547	113.2556671	2933	100.567323	2566	157.34747	4017	0.95278478	-0.285260825	normal	0.214133478	-0.547599626	normal	0.985081956	0.171159076	normal	0.543671054	-0.195155516	normal	--	--	--	--	--	--	--	NICE-3 protein	Uncharacterized protein C1orf43 GN=C1orf43 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf43 homolog isoform X1 [Tupaia chinensis]
ENSG00000143614(GATAD2B)	--	6.386849235	789	6.773119744	895	5.971612653	804	6.528068669	797	7.653896415	909	7.303183678	964	0.97673637	-0.016246363	normal	0.977860239	0.000964437	normal	0.934097311	0.253110858	normal	0.755656779	0.081149023	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[S]	Function unknown	GATA zinc finger	Transcriptional repressor p66-beta GN=GATAD2B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transcriptional repressor p66-beta isoform X1 [Sus scrofa]
ENSG00000143621(ILF2)	--	105.13136	3342	94.539733	3006	105.70989	3351	126.386477	4032	125.862926	3951	101.169828	3227	0.973133775	0.239851139	normal	0.873762644	0.372782244	normal	0.990122708	-0.062660732	normal	0.318870666	0.187198022	normal	--	--	--	K13089|0|mcf:102144475|ILF2; interleukin enhancer binding factor 2; K13089 interleukin enhancer-binding factor 2 (A)	--	[K]	Transcription	DZF domain	Interleukin enhancer-binding factor 2 GN=ILF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: interleukin enhancer-binding factor 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000143622(RIT1)	--	10.51293248	459	10.80554651	496	10.12026423	394	13.85227464	592	14.23581112	600	18.58700288	757	0.85133386	0.335280338	normal	0.926501935	0.252494991	normal	3.28E-05	0.931182709	normal	0.014980277	0.510028407	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07832|2.62471e-174|pps:100986791|RIT1; Ras-like without CAAX 1; K07832 Ras-like without CAAX 1 (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	GTP-binding protein Rit1 GN=RIT1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: GTP-binding protein Rit1 [Equus caballus]
ENSG00000143627(PKLR)	--	0.0217596	1	0.0212386	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: pyruvate kinase activity (GO:0004743);; Biological Process: glycolytic process (GO:0006096);; Molecular Function: potassium ion binding (GO:0030955);; 	"K12406|0|hsa:5313|PKLR, PK1, PKL, PKR, PKRL, RPK; pyruvate kinase, liver and RBC (EC:2.7.1.40); K12406 pyruvate kinase isozymes R/L [EC:2.7.1.40] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Purine metabolism (ko00230);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; Insulin signaling pathway (ko04910);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Maturity onset diabetes of the young (ko04950)	[G]	Carbohydrate transport and metabolism	"Pyruvate kinase, barrel domain;; Pyruvate kinase, alpha/beta domain"	Pyruvate kinase PKLR GN=PKLR OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: pyruvate kinase PKLR [Loxodonta africana]
ENSG00000143630(HCN3)	--	5.175310765	276	5.666722986	313	7.641480436	350	3.615315956	162	3.77708577	183	4.702908378	270	0.018310864	-0.793667014	normal	0.014656839	-0.79068672	normal	0.806463419	-0.380808145	normal	0.025200007	-0.629901957	normal	[T]	Signal transduction mechanisms	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04956|0|hsa:57657|HCN3; hyperpolarization activated cyclic nucleotide-gated potassium channel 3; K04956 hyperpolarization activated cyclic nucleotide-gated potassium channel 3 (A)	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein N-terminal;; Ion transport protein;; Cyclic nucleotide-binding domain	Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 GN=HCN3 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 [Orycteropus afer afer]
ENSG00000143631(FLG)	--	0.436265	169	0.290274	112	0.435111	169	0.67183	257	0.600866	233	0.58751	229	0.401872626	0.569685722	normal	0.000760785	1.025600283	up	0.787651316	0.426740471	normal	0.015020032	0.654924255	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; 	--	--	--	--	Filaggrin;; S-100/ICaBP type calcium binding domain;; double strand RNA binding domain from DEAD END PROTEIN 1;; Hemolysin-type calcium-binding repeat (2 copies)	Filaggrin GN=FLG OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	Filaggrin [Myotis brandtii]
ENSG00000143632(ACTA1)	--	0.07324153	2	0.0364643	1	0	0	0	0	0.048708042	0	0.107497346	3	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	--	"K10354|0|ssc:100154254|ACTA1, ACTA; actin, alpha 1, skeletal muscle; K10354 actin, alpha skeletal muscle (A)"	--	[Z]	Cytoskeleton	Actin	"Actin, alpha skeletal muscle (Precursor) GN=ACTA1 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"Actin, alpha 1, skeletal muscle [Bos taurus]"
ENSG00000143633(C1orf131)	--	9.293604	275	8.796479002	262	8.9554201	257	9.009317	269	12.213194	359	9.37037	278	0.965754026	-0.062305727	normal	0.710211078	0.430858057	normal	0.962619647	0.10443409	normal	0.599578721	0.16935197	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4602)	Uncharacterized protein C1orf131 GN=C1orf131 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C1orf131 homolog isoform X2 [Equus caballus]
ENSG00000143641(GALNT2)	--	80.0727	6750	75.9205	6545	80.7825	6938	98.9525	8378	85.7408	7186	72.8027	6165	0.975606764	0.280828653	normal	0.993135942	0.113344186	normal	0.989653196	-0.178669048	normal	0.743716327	0.080870675	normal	--	--	--	K00710|0|mcf:102116800|GALNT2; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; N-terminal domain of galactosyltransferase	Polypeptide N-acetylgalactosaminyltransferase 2 soluble form GN=GALNT2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 2 [Oryctolagus cuniculus]
ENSG00000143643(TTC13)	--	8.490559077	548	8.119450288	545	7.3701356	484	8.43186	519	8.494607	562	7.291375702	458	0.966731068	-0.108959642	normal	0.971914028	0.022824973	normal	0.967689903	-0.087669253	normal	0.865024612	-0.056877612	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3"	Tetratricopeptide repeat protein 13 GN=TTC13 OS=Homo sapiens (Human) PE=2 SV=3	GOT	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: tetratricopeptide repeat protein 13 isoform X1 [Oryctolagus cuniculus]
ENSG00000143653(SCCPDH)	--	31.33145	1211	35.09094	1387	32.98320578	1286	35.289557	1382	34.583687	1338	36.304181	1407	0.97185607	0.159536922	normal	0.980837765	-0.073234924	normal	0.977521008	0.121303827	normal	0.791476416	0.066354254	normal	[S]	Function unknown	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[S]	Function unknown	Saccharopine dehydrogenase	Saccharopine dehydrogenase-like oxidoreductase GN=SCCPDH OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: saccharopine dehydrogenase-like oxidoreductase [Tursiops truncatus]
ENSG00000143669(LYST)	--	1.626744266	352	2.366171539	503	2.512441095	423	2.634100262	416	2.527289229	392	2.053817554	431	0.943058493	0.209334623	normal	0.785979379	-0.379833994	normal	0.970199261	0.018672629	normal	0.848276962	-0.065916502	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; PH domain associated with Beige/BEACH;; WD domain, G-beta repeat"	Lysosomal-trafficking regulator GN=LYST OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: lysosomal-trafficking regulator [Ceratotherium simum simum]
ENSG00000143674(MAP3K21)	--	11.80828412	1157	12.86644353	1155	14.083323	1261	11.903237	1134	11.766491	1149	12.13070031	1075	0.979829405	-0.059720378	normal	0.980447642	-0.02890267	normal	0.947879144	-0.238213294	normal	0.624077398	-0.110701394	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17534|0|hsa:84451|KIAA1804, MLK4, dJ862P8.3; mixed lineage kinase 4 (EC:2.7.11.25); K17534 mitogen-activated protein kinase kinase kinase MLK4 [EC:2.7.11.25] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Mitogen-activated protein kinase kinase kinase MLK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase MLK4-like [Ceratotherium simum simum]
ENSG00000143702(CEP170)	--	16.43219969	1938	16.81259358	2041	17.80235192	1969	26.67586784	2799	26.00671867	2981	19.24839989	2161	0.366594701	0.499179716	normal	0.287636257	0.52477013	normal	0.982502409	0.125852223	normal	0.045569431	0.395059663	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K16463|0|ptr:457860|CEP170; centrosomal protein 170kDa; K16463 centrosomal protein CEP170 (A)	--	--	--	CEP170 C-terminus;; FHA domain	Centrosomal protein of 170 kDa GN=CEP170 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: centrosomal protein of 170 kDa isoform X2 [Tupaia chinensis]
ENSG00000143727(ACP1)	--	98.302524	2366	102.742518	2493	98.144732	2354	80.67578366	1991	78.74278004	1891	75.21296303	1823	0.943673047	-0.27959089	normal	0.720355571	-0.41986661	normal	0.821827053	-0.376815335	normal	0.020733517	-0.359898537	normal	[T]	Signal transduction mechanisms	--	"K14394|1.61166e-116|pps:100993518|ACP1; acid phosphatase 1, soluble; K14394 low molecular weight phosphotyrosine protein phosphatase [EC:3.1.3.2 3.1.3.48] (A)"	Riboflavin metabolism (ko00740)	[T]	Signal transduction mechanisms	Low molecular weight phosphotyrosine protein phosphatase	Low molecular weight phosphotyrosine protein phosphatase GN=ACP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: low molecular weight phosphotyrosine protein phosphatase isoformX1 [Equus caballus] 
ENSG00000143740(SNAP47)	--	15.34880562	637	13.945656	583	16.529989	675	17.3799872	706	17.46725167	689	14.2080053	576	0.968461543	0.117273796	normal	0.943851305	0.219058356	normal	0.936505322	-0.236535814	normal	0.912431504	0.035179127	normal	--	--	--	"K18212|0|hsa:116841|SNAP47, C1orf142, HEL170, SNAP-47, SVAP1; synaptosomal-associated protein, 47kDa; K18212 synaptosomal-associated protein 47 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	Synaptosomal-associated protein 47 GN=SNAP47 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptosomal-associated protein 47 isoform X1 [Physeter catodon]
ENSG00000143742(SRP9)	--	193.927818	3197	205.115238	3641	196.2567127	3293	215.526902	3793	191.570219	3370	206.035379	3564	0.977631196	0.215693111	normal	0.987319459	-0.132955288	normal	0.98890021	0.105756688	normal	0.809075211	0.06095249	normal	--	--	--	K03109|9.24793e-58|ptr:736942|SRP9; signal recognition particle 9kDa; K03109 signal recognition particle subunit SRP9 (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Signal recognition particle 9 kDa protein (SRP9)	Signal recognition particle 9 kDa protein GN=SRP9 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle 9 kDa protein [Galeopterus variegatus]
ENSG00000143748(NVL)	--	7.046265099	404	7.978212008	395	6.58440448	403	8.506780953	528	9.18842401	541	7.791408008	480	0.825869856	0.35416925	normal	0.660359001	0.430934402	normal	0.930147355	0.243126164	normal	0.10781001	0.344487619	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	K14571|0|pps:100980160|NVL; nuclear VCP-like; K14571 ribosome biogenesis ATPase (A)	Ribosome biogenesis in eukaryotes (ko03008)	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATPase family associated with various cellular activities (AAA);; Holliday junction DNA helicase ruvB N-terminus;; AAA domain;; AAA ATPase domain;; AAA domain (Cdc48 subfamily);; AAA domain;; AAA domain;; AAA domain (dynein-related subfamily);; AAA domain;; Zeta toxin;; TIP49 C-terminus;; AAA domain;; Part of AAA domain;; IstB-like ATP binding protein;; Magnesium chelatase, subunit ChlI;; AAA domain;; RNA helicase;; NACHT domain;; AAA domain;; ABC transporter;; KaiC;; ATPase family associated with various cellular activities (AAA);; Viral (Superfamily 1) RNA helicase;; Sigma-54 interaction domain"	Nuclear valosin-containing protein-like GN=NVL OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nuclear valosin-containing protein-like [Orcinus orca]
ENSG00000143751(SDE2)	--	5.17099	308	5.39167	325	4.31138	256	5.70825	343	6.17123	366	4.35791	259	0.960924895	0.123860302	normal	0.956465316	0.149322345	normal	0.967251011	0.008467118	normal	0.776989412	0.100566343	normal	--	--	--	--	--	[S]	Function unknown	Telomere stability and silencing;; Telomere stability C-terminal	Protein SDE2 homolog GN=SDE2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein SDE2 homolog [Vicugna pacos]
ENSG00000143753(DEGS1)	--	54.17944837	1714	56.51072003	1781	58.93953398	1772	74.138307	2313	65.50024807	2012	58.94142056	1831	0.756400543	0.401255274	normal	0.978086547	0.154392832	normal	0.985486636	0.03892906	normal	0.25992812	0.203111708	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K04712|0|hsa:8560|DEGS1, DEGS, DEGS-1, DES1, Des-1, FADS7, MLD; delta(4)-desaturase, sphingolipid 1 (EC:1.14.-.-); K04712 sphingolipid delta-4 desaturase [EC:1.14.-.-] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[I]	Lipid transport and metabolism	Fatty acid desaturase;; Sphingolipid Delta4-desaturase (DES)	Sphingolipid delta(4)-desaturase DES1 GN=DEGS1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	sphingolipid delta(4)-desaturase DES1 [Bos taurus] 
ENSG00000143756(FBXO28)	--	9.627091182	730	10.49046192	759	9.641813306	731	12.35263282	949	12.64026317	959	9.698846786	730	0.835881186	0.347037219	normal	0.883900804	0.315444124	normal	0.975936959	-0.010245175	normal	0.249129977	0.22696593	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10306|0|ptr:735792|FBXO28; F-box protein 28; K10306 F-box protein 28 (A)	--	--	--	F-box domain	F-box only protein 28 GN=FBXO28 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box only protein 28 [Vicugna pacos]
ENSG00000143761(ARF1)	--	162.849357	5425	161.6768356	5378	165.3119347	5555	193.016926	6506	190.0390657	6343	178.268992	6012	0.982659552	0.231255552	normal	0.984558303	0.216612891	normal	0.992588152	0.105738979	normal	0.352150257	0.184043965	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07937|5.11503e-132|ecb:100060911|ARF1; ADP-ribosylation factor 1; K07937 ADP-ribosylation factor 1 (A)	Endocytosis (ko04144);; Legionellosis (ko05134)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Ras family;; Gtr1/RagA G protein conserved region;; Miro-like protein;; 50S ribosome-binding GTPase	ADP-ribosylation factor 1 GN=ARF1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ADP-ribosylation factor 1 isoformX1 [Equus caballus] 
ENSG00000143771(CNIH4)	--	54.14707004	977	51.91138791	1057	48.754686	1002	67.67818002	1628	63.67541	1512	70.744775	1664	0.004949657	0.704970586	normal	0.380223936	0.494461822	normal	0.003072191	0.722626285	normal	7.61E-06	0.640863719	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Cornichon protein	Protein cornichon homolog 4 GN=CNIH4 OS=Homo sapiens (Human) PE=1 SV=1	OTU	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein cornichon homolog 4 isoform X1 [Mustela putorius furo] 
ENSG00000143772(ITPKB)	--	1.740436366	186	1.437600664	164	1.895743791	197	3.434598	370	3.9508815	421	2.68723441	287	0.00027263	0.955690403	normal	1.03E-08	1.330764635	up	0.475519984	0.531166322	normal	0.000106783	0.957223374	normal	--	--	"Molecular Function: inositol-1,4,5-trisphosphate 3-kinase activity (GO:0008440);; "	"K00911|0|hsa:3707|ITPKB, IP3-3KB, IP3K, IP3K-B, IP3KB, PIG37; inositol-trisphosphate 3-kinase B (EC:2.7.1.127); K00911 1D-myo-inositol-triphosphate 3-kinase [EC:2.7.1.127] (A)"	Inositol phosphate metabolism (ko00562);; Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070)	[I]	Lipid transport and metabolism	Inositol polyphosphate kinase	Inositol-trisphosphate 3-kinase B GN=ITPKB OS=Homo sapiens (Human) PE=1 SV=5	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: inositol-trisphosphate 3-kinase B [Equus caballus]
ENSG00000143774(GUK1)	--	52.98686913	852	57.14934197	946	49.90210651	841	84.90029531	1403	68.5319158	1065	73.5056058	1196	0.008307587	0.687781726	normal	0.969247168	0.149289761	normal	0.338326447	0.498992061	normal	0.007852684	0.451489604	normal	[F]	Nucleotide transport and metabolism	--	K00942|7.98293e-104|ptr:740432|GUK1; guanylate kinase 1; K00942 guanylate kinase [EC:2.7.4.8] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	Guanylate kinase;; Guanylate kinase	Guanylate kinase GN=GUK1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: guanylate kinase isoform X2 [Pteropus alecto] 
ENSG00000143776(CDC42BPA)	--	12.95964544	2497	14.72321583	2787	12.71372549	2346	12.82386246	2510	12.22411265	2400	13.2595932	2619	0.988710195	-0.023326405	normal	0.967047506	-0.236966439	normal	0.982362134	0.150429785	normal	0.882681313	-0.040541478	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	K16307|0|mcc:697811|CDC42BPA; CDC42 binding protein kinase alpha (DMPK-like); K16307 serine/threonine-protein kinase MRCK [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	CNH domain;; Protein kinase domain;; Protein tyrosine kinase;; DMPK coiled coil domain like;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Protein kinase C terminal domain	Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase MRCK alpha isoform X8 [Camelus bactrianus]
ENSG00000143786(CNIH3)	--	0.845109837	34	0.539093767	22	1.003261678	37	1.552045369	62	1.216676703	49	0.825027479	33	0.71224606	0.808491531	normal	0.478416115	1.082802752	normal	0.981288172	-0.166155704	normal	0.308175237	0.608350901	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Cornichon protein	Protein cornichon homolog 3 GN=CNIH3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	protein cornichon homolog 3 [Bos taurus] 
ENSG00000143793(C1orf35)	--	13.3191	392	12.2117	377	13.4534	419	17.117	514	17.5553	516	14.8788	445	0.819258528	0.358851009	normal	0.667871552	0.429900531	normal	0.967639637	0.078289428	normal	0.200237858	0.290767507	normal	--	--	--	--	--	[R]	General function prediction only	Kinase phosphorylation protein	Multiple myeloma tumor-associated protein 2 GN=MMTAG2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: multiple myeloma tumor-associated protein 2 [Oryctolagus cuniculus]
ENSG00000143797(MBOAT2)	--	9.219089651	986	7.327677819	854	8.12736976	929	8.402110089	992	8.646967776	961	5.74866441	673	0.97924139	-0.022045542	normal	0.967775352	0.148625594	normal	0.456162872	-0.472455885	normal	0.769995184	-0.098676085	normal	--	--	--	"K13517|0|hsa:129642|MBOAT2, LPCAT4, OACT2; membrane bound O-acyltransferase domain containing 2 (EC:2.3.1.51 2.3.1.n7); K13517 lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[S]	Function unknown	"MBOAT, membrane-bound O-acyltransferase family"	Lysophospholipid acyltransferase 2 GN=MBOAT2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: lysophospholipid acyltransferase 2 isoform X1 [Lipotes vexillifer]
ENSG00000143799(PARP1)	--	57.92824507	4281	50.69162342	4238	67.77621516	4543	73.579992	4753	61.86431461	4548	56.2429556	3737	0.990411659	0.120017413	normal	0.991436509	0.080394413	normal	0.957882624	-0.289949585	normal	0.938411638	-0.024398974	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; Biological Process: protein ADP-ribosylation (GO:0006471);; Molecular Function: zinc ion binding (GO:0008270);; 	"K10798|0|hsa:142|PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1; poly (ADP-ribose) polymerase 1 (EC:2.4.2.30); K10798 poly [ADP-ribose] polymerase [EC:2.4.2.30] (A)"	Base excision repair (ko03410);; NF-kappa B signaling pathway (ko04064)	[KLO]	"Transcription;; Replication, recombination and repair;; Posttranslational modification, protein turnover, chaperones"	"Poly(ADP-ribose) polymerase catalytic domain;; Poly(ADP-ribose) polymerase, regulatory domain;; Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region;; PADR1 (NUC008) domain;; WGR domain;; BRCA1 C Terminus (BRCT) domain"	Poly [ADP-ribose] polymerase 1 GN=PARP1 OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: poly [ADP-ribose] polymerase 1 [Tupaia chinensis]
ENSG00000143801(PSEN2)	--	14.19990044	550	13.78292537	525	13.71971861	538	13.9015783	529	15.53664312	585	15.83126302	605	0.969046787	-0.086749031	normal	0.96320596	0.134325968	normal	0.959612663	0.160611571	normal	0.818123765	0.071070805	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein processing (GO:0016485);; 	K04522|0|nle:100596029|PSEN2; presenilin 2 (Alzheimer disease 4); K04522 presenilin 2 [EC:3.4.23.-] (A)	Notch signaling pathway (ko04330);; Neurotrophin signaling pathway (ko04722);; Alzheimer's disease (ko05010)	[T]	Signal transduction mechanisms	Presenilin	Presenilin-2 CTF subunit GN=PSEN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: presenilin-2 isoform X1 [Sus scrofa]
ENSG00000143811(PYCR2)	--	39.726696	1150	35.84442503	1092	39.09321664	1203	33.99974541	1034	31.95415284	941	35.25004951	1057	0.964134452	-0.18397056	normal	0.945899005	-0.235780652	normal	0.96219254	-0.194691408	normal	0.281185526	-0.205262324	normal	[E]	Amino acid transport and metabolism	--	"K00286|0|pps:100969152|PYCR2; pyrroline-5-carboxylate reductase family, member 2; K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] (A)"	Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Pyrroline-5-carboxylate reductase dimerisation;; NADP oxidoreductase coenzyme F420-dependent;; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	Pyrroline-5-carboxylate reductase 2 GN=PYCR2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: pyrroline-5-carboxylate reductase 2 isoform X1 [Camelus ferus] 
ENSG00000143815(LBR)	--	40.47239	2050	37.410514	1885	38.49728513	1907	43.958985	2250	40.40671	2045	36.63165	1856	0.984595495	0.103394846	normal	0.983753479	0.096035779	normal	0.985710929	-0.047361503	normal	0.83571174	0.052547009	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Ergosterol biosynthesis ERG4/ERG24 family;; Lamin-B receptor of TUDOR domain;; Protein of unknown function (DUF1295);; Phospholipid methyltransferase	Lamin-B receptor GN=LBR OS=Homo sapiens (Human) PE=1 SV=2	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: lamin-B receptor [Orcinus orca]
ENSG00000143816(WNT9A)	--	2.458786	166	2.68789	192	2.669499	185	2.726173	185	1.446394	99	1.861169	126	0.961564978	0.124418622	normal	0.005111902	-0.966234933	normal	0.574638208	-0.556843059	normal	0.211781374	-0.428009338	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K01064|0|ptr:469697|WNT9A; wingless-type MMTV integration site family, member 9A; K01064 wingless-type MMTV integration site family, member 9 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-9a (Precursor) GN=WNT9A OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: basic proline-rich protein-like [Leptonychotes weddellii]
ENSG00000143819(EPHX1)	--	89.883865	2578	91.572855	2578	83.444557	2347	56.40306222	1693	77.81813154	2195	83.51285245	2466	0.02457086	-0.637030258	normal	0.959618686	-0.25329665	normal	0.987556776	0.063023895	normal	0.244202446	-0.260010466	normal	[R]	General function prediction only	--	"K01253|0|hsa:2052|EPHX1, EPHX, EPOX, HYL1, MEH; epoxide hydrolase 1, microsomal (xenobiotic) (EC:3.3.2.9); K01253 microsomal epoxide hydrolase [EC:3.3.2.9] (A)"	Metabolism of xenobiotics by cytochrome P450 (ko00980);; Bile secretion (ko04976);; Chemical carcinogenesis (ko05204)	[R]	General function prediction only	Epoxide hydrolase N terminus;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Epoxide hydrolase 1 GN=EPHX1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	Epoxide hydrolase 1 [Tupaia chinensis]
ENSG00000143839(REN)	--	1.490610515	4	0	0	1.712090431	4	0.370636951	2	0.371563229	2	0.661633931	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Biological Process: proteolysis (GO:0006508);; 	K01380|0|ptr:469651|REN; renin (EC:3.4.23.15); K01380 renin [EC:3.4.23.15] (A)	Renin-angiotensin system (ko04614)	[O]	"Posttranslational modification, protein turnover, chaperones"	Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal;; Xylanase inhibitor C-terminal;; A1 Propeptide;; Aspartyl protease	Renin (Precursor) GN=REN OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: renin [Galeopterus variegatus]
ENSG00000143842(SOX13)	--	4.394457698	355	4.59534466	351	4.649737705	375	4.872869706	385	4.400614007	333	3.865235584	282	0.965687052	0.085850326	normal	0.963320397	-0.096946506	normal	0.728994817	-0.41753836	normal	0.673671203	-0.134384708	normal	--	--	--	"K09269|0|hsa:9580|SOX13, ICA12, Sox-13; SRY (sex determining region Y)-box 13; K09269 transcription factor SOX5/6/13 (SOX group D) (A)"	--	[K]	Transcription	HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-13 GN=SOX13 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor SOX-13 [Orycteropus afer afer]
ENSG00000143845(ETNK2)	--	5.12879944	224	4.224700665	160	3.269605025	141	2.865863195	131	6.292454283	222	3.913089654	140	0.034276761	-0.797519837	normal	0.760197836	0.447456451	normal	0.968089641	-0.018362133	normal	0.880007499	-0.111929811	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K00894|0|hsa:55224|ETNK2, EKI2, HMFT1716; ethanolamine kinase 2 (EC:2.7.1.82); K00894 ethanolamine kinase [EC:2.7.1.82] (A)"	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Choline/ethanolamine kinase;; Phosphotransferase enzyme family	Ethanolamine kinase 2 GN=ETNK2 OS=Homo sapiens (Human) PE=2 SV=3	I	Lipid transport and metabolism	PREDICTED: ethanolamine kinase 2 isoform 1 [Orcinus orca] 
ENSG00000143847(PPFIA4)	--	1.08201809	143	1.220580023	171	0.88308396	116	0.709795384	97	0.30774004	45	0.5859297	56	0.62541189	-0.583131851	normal	3.39E-10	-1.911999625	down	0.023187438	-1.03899856	normal	0.002667011	-1.142710856	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Liprin-alpha-4 GN=PPFIA4 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: liprin-alpha-4 isoform X1 [Elephantulus edwardii]
ENSG00000143850(PLEKHA6)	--	18.39089604	579	3.711251179	599	16.9696025	627	44.8731381	1558	56.279474	1513	42.33342352	1931	7.54E-14	1.394882393	up	7.00E-12	1.313198727	up	0	1.612186508	up	4.44E-14	1.450042027	up	--	--	--	--	--	--	--	PH domain;; Pleckstrin homology domain	Pleckstrin homology domain-containing family A member 6 GN=PLEKHA6 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family A member 6 isoform X3 [Tupaia chinensis]
ENSG00000143851(PTPN7)	--	0	0	0.245907882	3	0.0558117	3	0.015367885	1	0.336299164	0	0.025456777	2	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18019|0|pps:100973100|PTPN7; protein tyrosine phosphatase, non-receptor type 7; K18019 tyrosine-protein phosphatase non-receptor type 7 [EC:3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase	Tyrosine-protein phosphatase non-receptor type 7 GN=PTPN7 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: tyrosine-protein phosphatase non-receptor type 7 [Tupaia chinensis]
ENSG00000143858(SYT2)	--	0.101859	16	0.124873909	20	0.080870757	12	0.057111317	9	0.062255556	9	0.069678629	11	--	--	--	0.941104135	-1.052217007	normal	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-2 GN=SYT2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-2 [Ochotona princeps]
ENSG00000143862(ARL8A)	--	23.343038	818	23.61470363	831	23.114308	820	24.153306	848	24.77632	862	25.155099	887	0.977238475	0.021092249	normal	0.976713367	0.031356806	normal	0.973080341	0.104832819	normal	0.857800023	0.051855997	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07955|7.69519e-136|pps:100974027|ARL8A; ADP-ribosylation factor-like 8A; K07955 ADP-ribosylation factor-like protein 8 (A)	--	[R]	General function prediction only	ADP-ribosylation factor family;; Ras family;; Miro-like protein;; Gtr1/RagA G protein conserved region;; Signal recognition particle receptor beta subunit;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	ADP-ribosylation factor-like protein 8A GN=ARL8A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 8A [Echinops telfairi]
ENSG00000143867(OSR1)	--	4.823634	158	4.546872	148	4.33754979	146	4.906601	161	5.185016437	170	3.417263	113	0.967616994	-0.003660869	normal	0.954434556	0.176824144	normal	0.896755577	-0.373526909	normal	0.940283296	-0.047897155	normal	[R]	General function prediction only	--	"K09215|2.89841e-180|hsa:130497|OSR1, ODD; odd-skipped related transciption factor 1; K09215 odd-skipped (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Protein odd-skipped-related 1 GN=OSR1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: protein odd-skipped-related 1 [Galeopterus variegatus] 
ENSG00000143869(GDF7)	--	0.0519513	9	0.0560921	10	0.0501624	8	0.0803852	14	0.0560598	9	0.034319	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04664|1.76634e-168|hsa:151449|GDF7, BMP12; growth differentiation factor 7; K04664 growth differentiation factor 5/6/7 (A)"	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390)	--	--	Transforming growth factor beta like domain;; TGF-beta propeptide	Growth/differentiation factor 7 (Precursor) GN=GDF7 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: growth/differentiation factor 7 [Ceratotherium simum simum]
ENSG00000143870(PDIA6)	--	288.7094462	10613	265.9821323	10280	271.3384424	10356	212.0612034	8075	199.2772634	7332	211.9448989	7879	0.8456995	-0.425059823	normal	0.534854057	-0.508899028	normal	0.888140235	-0.40260625	normal	0.006507852	-0.44565911	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	"K09584|0|hsa:10130|PDIA6, ERP5, P5, TXNDC7; protein disulfide isomerase family A, member 6 (EC:5.3.4.1); K09584 protein disulfide-isomerase A6 [EC:5.3.4.1] (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like;; Thioredoxin-like domain;; Thioredoxin-like	Protein disulfide-isomerase A6 (Precursor) GN=PDIA6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein disulfide-isomerase A6 [Equus caballus]
ENSG00000143878(RHOB)	--	62.9758	2430	47.4528	1871	56.7322	2254	49.3025	1921	40.6289	1568	49.2221	1911	0.839058387	-0.369667465	normal	0.9393552	-0.276066445	normal	0.958593605	-0.246271513	normal	0.135442932	-0.30079567	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07856|3.94151e-143|ssc:100144503|RHOB; ras homolog family member B; K07856 Ras homolog gene family, member B (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Rho-related GTP-binding protein RhoB (Precursor) GN=RHOB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoB-like [Myotis lucifugus] 
ENSG00000143882(ATP6V1C2)	--	0.456359491	26	0.615918279	35	0.314344311	17	0.168643711	10	0.11881787	6	0.45081383	26	0.78509553	-1.283061262	normal	0.004455639	-2.29988521	down	0.974401774	0.563868021	normal	0.323512648	-0.912208712	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V1 domain (GO:0033180);; "	"K02148|0|mcf:102137126|ATP6V1C2; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2; K02148 V-type H+-transporting ATPase subunit C (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	V-ATPase subunit C	V-type proton ATPase subunit C 2 GN=ATP6V1C2 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit C 2 [Felis catus]
ENSG00000143889(HNRNPLL)	--	19.0413583	927	24.32613586	1173	21.65691833	1042	19.69415002	953	18.67381316	904	18.15193636	863	0.978797377	0.009059802	normal	0.741089927	-0.396650554	normal	0.918394668	-0.279767396	normal	0.223420472	-0.229629599	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K13159|0|pale:102885077|HNRNPLL; heterogeneous nuclear ribonucleoprotein L-like; K13159 heterogeneous nuclear ribonucleoprotein L (A)	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoprotein L-like GN=HNRNPLL OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein L-like [Camelus dromedarius]
ENSG00000143891(GALM)	--	15.62484764	765	17.03213568	850	14.76950758	734	8.794603038	436	9.614685459	467	11.34391551	562	0.000359819	-0.839698375	normal	0.000118776	-0.883313411	normal	0.739587842	-0.392574166	normal	1.87E-05	-0.701765803	normal	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: isomerase activity (GO:0016853);; 	"K01785|0|hsa:130589|GALM, GLAT, HEL-S-63p, IBD1; galactose mutarotase (aldose 1-epimerase) (EC:5.1.3.3); K01785 aldose 1-epimerase [EC:5.1.3.3] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Galactose metabolism (ko00052)	[G]	Carbohydrate transport and metabolism	Aldose 1-epimerase	Aldose 1-epimerase GN=GALM OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: aldose 1-epimerase [Tupaia chinensis] 
ENSG00000143919(CAMKMT)	--	7.60734009	79	4.248099063	44	7.656770259	69	6.88446378	72	8.359506459	74	6.15759052	69	0.969426646	-0.161398375	normal	0.735380462	0.709599286	normal	0.974872947	-0.008113615	normal	0.840739223	0.142266715	normal	--	--	--	"K18826|0|hsa:79823|CAMKMT, C2orf34, CLNMT, CaM_KMT, Cam, KMT; calmodulin-lysine N-methyltransferase (EC:2.1.1.60); K18826 calmodulin-lysine N-methyltransferase [EC:2.1.1.60] (A)"	Lysine degradation (ko00310)	[S]	Function unknown	Putative methyltransferase	Calmodulin-lysine N-methyltransferase GN=CAMKMT OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: calmodulin-lysine N-methyltransferase [Equus caballus]
ENSG00000143924(EML4)	--	43.88152233	4475	46.99717904	4771	43.61533159	4379	20.33043286	2078	22.27880057	2262	18.84429199	1923	6.26E-10	-1.136936532	down	7.04E-09	-1.097601778	down	5.11E-11	-1.194893469	down	1.23E-17	-1.142789363	down	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K15420|0|pps:100968189|EML4; echinoderm microtubule associated protein like 4; K15420 echinoderm microtubule-associated protein-like 4 (A)	Non-small cell lung cancer (ko05223)	[S]	Function unknown	"HELP motif;; WD domain, G-beta repeat"	Echinoderm microtubule-associated protein-like 4 GN=EML4 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: echinoderm microtubule-associated protein-like 4 [Camelus dromedarius]
ENSG00000143933(CALM2)	--	607.226158	11730	612.3939126	12131	676.8476802	13039	504.3412505	9977	439.712955	8414	403.3008093	7725	0.984782204	-0.264319706	normal	0.350072019	-0.549178616	normal	0.001287525	-0.763401456	normal	0.001274083	-0.520532645	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	K02183|9.04353e-98|pss:102456219|calmodulin-like; K02183 calmodulin (A)	Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Phototransduction (ko04744);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916)	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain;; Cytoskeletal-regulatory complex EF hand;; Secreted protein acidic and rich in cysteine Ca binding region;; Ca2+ insensitive EF hand;; Uncharacterised protein family (UPF0154);; Putative binding domain	Calmodulin GN=CALM3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: calmodulin, partial [Equus przewalskii]"
ENSG00000143942(CHAC2)	--	10.27951	201	12.15943	237	12.16696	236	8.82667	176	10.24823	201	8.247553	163	0.944683919	-0.220648192	normal	0.928644531	-0.257332773	normal	0.525018904	-0.538033742	normal	0.275179421	-0.341005551	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: gamma-glutamylcyclotransferase activity (GO:0003839);; Biological Process: glutathione catabolic process (GO:0006751);; 	--	--	[P]	Inorganic ion transport and metabolism	ChaC-like protein	Putative glutathione-specific gamma-glutamylcyclotransferase 2 {ECO:0000250|UniProtKB:Q9BUX1} OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: cation transport regulator-like protein 2 [Erinaceus europaeus]
ENSG00000143947(RPS27A)	--	674.5827	9599	672.0645294	9848	631.9101508	9116	649.540441	9453	594.9449555	8471	521.502666	7530	0.995885513	-0.052935587	normal	0.986632792	-0.238685466	normal	0.976376008	-0.283990581	normal	0.363421068	-0.188253255	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: structural constituent of ribosome (GO:0003735);; Molecular Function: protein binding (GO:0005515);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02977|2.2042e-83|xtr:548926|rps27a; ribosomal protein S27a; K02977 small subunit ribosomal protein S27Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ubiquitin family;; Ribosomal protein S27a;; Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin-like domain	40S ribosomal protein S27a (Precursor) GN=RPS27A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ubiquitin-40S ribosomal protein S27a [Sarcophilus harrisii]
ENSG00000143951(WDPCP)	--	2.4662732	158	3.281270971	175	2.0217517	132	1.68612707	115	1.92478745	117	2.51893278	116	0.774770234	-0.48358527	normal	0.497752155	-0.595930029	normal	0.957399148	-0.192352036	normal	0.221392905	-0.439716494	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3312)	WD repeat-containing and planar cell polarity effector protein fritz homolog GN=WDPCP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: WD repeat-containing and planar cell polarity effector protein fritz homolog [Balaenoptera acutorostrata scammoni]
ENSG00000143952(VPS54)	--	11.1823	875	11.50153213	873	11.528776	857	9.310141432	764	10.65895973	845	10.791324	829	0.945362172	-0.226117309	normal	0.975399183	-0.068336538	normal	0.976377185	-0.05611386	normal	0.624077398	-0.116530299	normal	--	--	"Biological Process: retrograde transport, endosome to Golgi (GO:0042147);; "	K17600|0|nle:100583705|VPS54; vacuolar protein sorting 54 homolog (S. cerevisiae); K17600 vacuolar protein sorting-associated protein 54 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vps54-like protein;; Protein of unknown function N-terminal domain (DUF2450)	Vacuolar protein sorting-associated protein 54 GN=VPS54 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 54 isoform 1 [Odobenus rosmarus divergens]
ENSG00000143970(ASXL2)	--	10.87188673	2155	13.64646096	2645	13.00542336	2511	9.09586789	1830	8.806225534	1744	10.581997	2156	0.948226119	-0.266470033	normal	0.043398101	-0.621852993	normal	0.967296742	-0.228047917	normal	0.02408617	-0.372222306	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: transcription, DNA-templated (GO:0006351);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K11471|0|hsa:55252|ASXL2, ASXH2; additional sex combs like transcriptional regulator 2; K11471 additional sex combs-like protein (A)"	--	--	--	"Asx homology domain;; PHD domain of transcriptional enhancer, Asx;; HB1, ASXL, restriction endonuclease HTH domain"	Putative Polycomb group protein ASXL2 GN=ASXL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: putative Polycomb group protein ASXL2 [Galeopterus variegatus]
ENSG00000143971(ETAA1)	--	8.27193	532	7.98008	508	8.27409	519	7.33182	475	7.32828	471	7.07793	456	0.94980017	-0.193738423	normal	0.96241692	-0.130125565	normal	0.949501708	-0.194387424	normal	0.494096591	-0.174431272	normal	--	--	--	--	--	--	--	Ewing's tumour-associated antigen 1 homologue	Ewing's tumor-associated antigen 1 GN=ETAA1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ewing's tumor-associated antigen 1 homolog isoform X3 [Physeter catodon]
ENSG00000143977(SNRPG)	--	162.4914115	1210	175.9309494	1343	182.0528367	1383	181.6246114	1397	164.854023	1219	146.2719746	1099	0.968869188	0.176284263	normal	0.971185661	-0.160997354	normal	0.861426009	-0.339483821	normal	0.642689264	-0.10517573	normal	[K]	Transcription	--	K11099|3.9316e-55|ggo:101144036|SNRPG; small nuclear ribonucleoprotein G; K11099 small nuclear ribonucleoprotein G (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	Small nuclear ribonucleoprotein G GN=SNRPG OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: small nuclear ribonucleoprotein G-like [Odobenus rosmarus divergens]
ENSG00000143994(ABHD1)	--	0.770423	17	0.855255	19	1.775875	25	0.043784833	1	0.23679243	4	0.489322	7	--	--	--	--	--	--	0.502873889	-1.646360853	normal	--	--	--	[R]	General function prediction only	--	"K13696|0|hsa:84696|ABHD1, LABH1; abhydrolase domain containing 1; K13696 abhydrolase domain-containing protein 1/3 (A)"	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold	Abhydrolase domain-containing protein 1 GN=ABHD1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: abhydrolase domain-containing protein 1 [Orycteropus afer afer]
ENSG00000143995(MEIS1)	--	1.398084108	68	0.958567498	44	0.9474506	65	0.695101428	44	0.9765346	49	1.140920547	63	0.838438265	-0.640718813	normal	0.976974529	0.129628435	normal	0.975406281	-0.052146913	normal	0.775110276	-0.201956513	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K15613|0|myd:102751967|MEIS1; Meis homeobox 1; K15613 homeobox protein Meis1 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein Meis1 GN=MEIS1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox protein Meis2 isoform X1 [Myotis davidii]
ENSG00000144021(CIAO1)	--	41.17962	1919	39.39727	1866	43.12978	1941	31.49017	1559	35.55579	1624	27.63416	1386	0.889287937	-0.330272038	normal	0.963161328	-0.221631189	normal	0.367100394	-0.493706873	normal	0.028030224	-0.347080097	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Anaphase-promoting complex subunit 4 WD40 domain;; Eukaryotic translation initiation factor eIF2A;; IKI3 family"	Probable cytosolic iron-sulfur protein assembly protein CIAO1 {ECO:0000255|HAMAP-Rule:MF_03037} OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: probable cytosolic iron-sulfur protein assembly protein CIAO1 [Orycteropus afer afer]
ENSG00000144026(ZNF514)	--	9.247532	914	9.8468945	925	10.14587461	858	6.641492628	570	6.30971549	550	5.137466	536	0.006751847	-0.710536738	normal	0.001992183	-0.769796773	normal	0.013331677	-0.685493012	normal	4.24E-06	-0.725153327	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:84874|ZNF514; zinc finger protein 514; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 514 GN=ZNF514 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 514 [Galeopterus variegatus]
ENSG00000144028(SNRNP200)	--	57.01193028	9276	60.64165345	9951	57.98192256	9464	36.95665425	5986	37.93695157	6109	40.481502	6554	0.020575183	-0.662604983	normal	0.004851825	-0.725189689	normal	0.330678698	-0.538261886	normal	2.20E-05	-0.642461063	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K12854|0|ptr:459413|SNRNP200, ASCC3L1; small nuclear ribonucleoprotein 200kDa (U5); K12854 pre-mRNA-splicing helicase BRR2 [EC:3.6.4.13] (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	"Sec63 Brl domain;; DEAD/DEAH box helicase;; Type III restriction enzyme, res subunit;; Helicase conserved C-terminal domain;; AAA domain;; PhoH-like protein"	U5 small nuclear ribonucleoprotein 200 kDa helicase GN=SNRNP200 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U5 small nuclear ribonucleoprotein 200 kDa helicase [Camelus ferus] 
ENSG00000144029(MRPS5)	--	40.4212	1299	38.1717	1257	40.2236	1312	26.4943	860	29	925	27.7451	892	0.036277909	-0.624909636	normal	0.508630573	-0.463233485	normal	0.124494087	-0.564149874	normal	0.000223914	-0.551964297	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02988|0|hsa:64969|MRPS5, MRP-S5, S5mt; mitochondrial ribosomal protein S5; K02988 small subunit ribosomal protein S5 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein S5, C-terminal domain;; Ribosomal protein S5, N-terminal domain"	"28S ribosomal protein S5, mitochondrial GN=MRPS5 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S5, mitochondrial [Mustela putorius furo]"
ENSG00000144031(ANKRD53)	--	0.0287702	1	0.022441881	1	0.087352986	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 53 GN=ANKRD53 OS=Homo sapiens (Human) PE=2 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 53-like [Galeopterus variegatus]
ENSG00000144034(TPRKB)	--	38.52179	391	36.63102	369	52.70992	530	37.47113	395	34.78688	341	29.95181	303	0.969437493	-0.016085333	normal	0.958983951	-0.134701172	normal	0.001858392	-0.811861656	normal	0.2819164	-0.333548221	normal	--	--	--	K15901|3.24837e-116|hsa:51002|TPRKB; TP53RK binding protein; K15901 EKC/KEOPS complex subunit CGI121/TPRKB (A)	--	[S]	Function unknown	Kinase binding protein CGI-121	EKC/KEOPS complex subunit TPRKB GN=TPRKB OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: EKC/KEOPS complex subunit TPRKB isoform X1 [Erinaceus europaeus]
ENSG00000144035(NAT8)	--	0	0	0.148964	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[KR]	Transcription;; General function prediction only	"Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	--	--	[R]	General function prediction only	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; GCN5-related N-acetyl-transferase;; Acetyltransferase (GNAT) domain;; FR47-like protein	N-acetyltransferase 8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: probable N-acetyltransferase 8-like isoform X1 [Myotis davidii] 
ENSG00000144036(EXOC6B)	--	14.04472582	1415	14.08156916	1482	12.81351808	1365	10.904916	1208	13.031197	1411	11.125274	1251	0.940477611	-0.258709434	normal	0.980449304	-0.092157626	normal	0.975723981	-0.133955524	normal	0.420584226	-0.160324808	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: vesicle docking involved in exocytosis (GO:0006904);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex subunit Sec15-like	Exocyst complex component 6B GN=EXOC6B OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 6B isoform X1 [Felis catus] 
ENSG00000144043(TEX261)	--	46.9498415	2527	49.9370003	2718	48.923613	2644	48.193661	2590	45.5216147	2420	47.1597598	2534	0.989002734	0.004691353	normal	0.97756752	-0.18885353	normal	0.987991879	-0.069556452	normal	0.711480135	-0.085794096	normal	--	--	--	--	--	[TI]	Signal transduction mechanisms;; Lipid transport and metabolism	Transmembrane adaptor Erv26	Protein TEX261 GN=TEX261 OS=Homo sapiens (Human) PE=2 SV=1	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: protein TEX261 isoform X1 [Ochotona princeps]
ENSG00000144045(DQX1)	--	0.020364283	1	0.147312439	8	0.10898799	5	0	0	0.03828856	1	0.081101674	4	--	--	--	--	--	--	--	--	--	--	--	--	[L]	"Replication, recombination and repair"	Molecular Function: helicase activity (GO:0004386);; 	K14433|0|hsa:165545|DQX1; DEAQ box RNA-dependent ATPase 1 (EC:3.6.4.12); K14433 ATP-dependent RNA helicase DQX1 [EC:3.6.4.12] (A)	--	[A]	RNA processing and modification	Helicase associated domain (HA2);; Oligonucleotide/oligosaccharide-binding (OB)-fold	ATP-dependent RNA helicase DQX1 GN=DQX1 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DQX1 [Galeopterus variegatus] 
ENSG00000144048(DUSP11)	--	16.732051	436	14.95117523	397	14.93097068	393	15.13723497	406	14.5592127	388	15.12919979	403	0.961231492	-0.133194113	normal	0.967419627	-0.054299677	normal	0.969413778	0.02785324	normal	0.879049896	-0.055846829	normal	--	--	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K14165|0|hsa:8446|DUSP11, PIR1; dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) (EC:3.1.3.16 3.1.3.48); K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	--	[A]	RNA processing and modification	"Dual specificity phosphatase, catalytic domain"	RNA/RNP complex-1-interacting phosphatase GN=DUSP11 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: RNA/RNP complex-1-interacting phosphatase [Ailuropoda melanoleuca]
ENSG00000144057(ST6GAL2)	--	0.200417111	17	0.268194584	28	0.334772538	23	2.770254	283	2.342442269	244	3.485645	307	0	3.910703756	up	0	3.035595965	up	0	3.645735535	up	1.05E-34	3.595366256	up	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K00779|0|hsa:84620|ST6GAL2, SIAT2, ST6GalII; ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 (EC:2.4.99.1); K00779 beta-galactoside alpha2,6-sialyltransferase (sialyltransferase 2) [EC:2.4.99.1] (A)"	N-Glycan biosynthesis (ko00510);; Other types of O-glycan biosynthesis (ko00514)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Beta-galactoside alpha-2,6-sialyltransferase 2 GN=ST6GAL2 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-galactoside alpha-2,6-sialyltransferase 2 [Felis catus]"
ENSG00000144061(NPHP1)	--	8.836277279	173	5.34310657	127	9.41335745	154	4.2596381	80	3.79216608	94	3.597171866	85	0.000577425	-1.128417115	down	0.855617071	-0.449278915	normal	0.061891162	-0.854230266	normal	0.010870721	-0.830570427	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Nephrocystin-1 GN=NPHP1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: nephrocystin-1 isoform X3 [Canis lupus familiaris]
ENSG00000144063(MALL)	--	84.438851	3588	78.5788355	3441	73.19618903	3204	78.16164	3364	64.50371562	2752	52.27540448	2279	0.98807735	-0.123779692	normal	0.906761756	-0.343604725	normal	0.379093828	-0.499483732	normal	0.141811262	-0.308162932	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Membrane-associating domain	MAL-like protein GN=MALL OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: MAL-like protein [Bubalus bubalis]
ENSG00000144118(RALB)	--	26.32135719	1052	26.79180342	1107	29.70720422	1202	34.71721765	1350	29.91368893	1182	22.62864723	913	0.875247329	0.328567926	normal	0.978724124	0.073051669	normal	0.708487763	-0.404455789	normal	0.975760373	0.01347291	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07835|3.9801e-133|pps:100972167|RALB; v-ral simian leukemia viral oncogene homolog B; K07835 Ras-related protein Ral-B (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Pathways in cancer (ko05200);; Pancreatic cancer (ko05212)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Signal recognition particle receptor beta subunit	Ras-related protein Ral-B (Precursor) GN=RALB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related protein Ral-B [Camelus ferus] 
ENSG00000144119(C1QL2)	--	0.130951	4	0	0	0.121602	3	0	0	0.0314714	0	0.0320838	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	Complement C1q-like protein 2 (Precursor) GN=C1QL2 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: complement C1q-like protein 2 [Orycteropus afer afer]
ENSG00000144120(TMEM177)	--	18.25987553	345	17.68585331	329	20.94933072	391	14.5443873	280	12.17848531	228	10.33994085	217	0.870832493	-0.330365147	normal	0.382468603	-0.547439459	normal	0.001900084	-0.853270184	normal	0.009813598	-0.576542396	normal	--	--	--	--	--	--	--	--	Transmembrane protein 177 GN=TMEM177 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 177 [Eptesicus fuscus]
ENSG00000144130(NT5DC4)	--	0.0611108	2	0.0899262	3	0	0	0.0303305	1	0	0	0.0906306	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	5' nucleotidase family	5'-nucleotidase domain-containing protein 4 GN=NT5DC4 OS=Homo sapiens (Human) PE=2 SV=2	F	Nucleotide transport and metabolism	PREDICTED: 5'-nucleotidase domain-containing protein 4 [Ceratotherium simum simum]
ENSG00000144134(RABL2A)	--	1.91788208	68	2.833603389	91	2.823837962	105	1.705171805	51	1.104908125	39	2.05519976	52	0.937647398	-0.434491327	normal	0.01272166	-1.212136962	normal	0.05718751	-1.001193175	normal	0.029138849	-0.915434653	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07931|3.11815e-151|mcf:102146752|RABL2B; RAB, member of RAS oncogene family-like 2B; K07931 Rab-like protein 2 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	Rab-like protein 2A GN=RABL2A OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab-like protein 2A-like isoform X2 [Equus caballus] 
ENSG00000144136(SLC20A1)	--	58.26088	3028	53.5681	2705	54.352128	2849	41.13666878	2179	40.988199	2132	49.51677	2562	0.345522066	-0.505227534	normal	0.862493013	-0.364617496	normal	0.982225389	-0.161386204	normal	0.030348921	-0.341086835	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: inorganic phosphate transmembrane transporter activity (GO:0005315);; Biological Process: phosphate ion transport (GO:0006817);; Cellular Component: membrane (GO:0016020);; 	"K14640|0|hsa:6574|SLC20A1, GLVR1, Glvr-1, PIT1, PiT-1; solute carrier family 20 (phosphate transporter), member 1; K14640 solute carrier family 20 (sodium-dependent phosphate transporter) (A)"	--	[P]	Inorganic ion transport and metabolism	Phosphate transporter family	Sodium-dependent phosphate transporter 1 GN=SLC20A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transporter 1 [Leptonychotes weddellii]
ENSG00000144152(FBLN7)	--	1.006599492	35	0.86785244	34	0.874188495	34	0.208890764	8	0.452421919	16	0.217009201	7	0.027625674	-1.965511192	normal	0.79527844	-1.039996066	normal	0.020965775	-2.068077919	normal	0.002750843	-1.753395037	down	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K17342|0|ptr:470481|FBLN7; fibulin 7; K17342 fibulin 7 (A)	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Sushi domain (SCR repeat);; EGF-like domain	Fibulin-7 (Precursor) GN=FBLN7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: fibulin-7 isoform 1 [Ceratotherium simum simum]
ENSG00000144161(ZC3H8)	--	8.570543	336	8.385110694	375	7.040719367	275	7.331138467	293	6.536919	247	5.94604876	226	0.936873605	-0.227278777	normal	0.148321961	-0.620698092	normal	0.910930567	-0.289640338	normal	0.123099924	-0.38671736	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[A]	RNA processing and modification	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 8 GN=ZC3H8 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: zinc finger CCCH domain-containing protein 8 isoform X1 [Panthera tigris altaica] 
ENSG00000144182(LIPT1)	--	28.098149	1354	24.33324857	1255	28.46216675	1362	21.54620327	1106	22.21094682	1101	17.97075847	901	0.88420812	-0.322303125	normal	0.958451229	-0.210029013	normal	0.057209629	-0.603589119	normal	0.019356102	-0.37516487	normal	[H]	Coenzyme transport and metabolism	--	K10105|0|hsa:51601|LIPT1; lipoyltransferase 1 (EC:2.3.1.181); K10105 lipoyltransferase 1 (A)	Lipoic acid metabolism (ko00785)	[H]	Coenzyme transport and metabolism	Biotin/lipoate A/B protein ligase family	"Lipoyltransferase 1, mitochondrial (Precursor) GN=LIPT1 OS=Homo sapiens (Human) PE=1 SV=1"	H	Coenzyme transport and metabolism	"PREDICTED: lipoyltransferase 1, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000144199(FAHD2B)	--	9.720138	239	9.579032497	232	8.725881801	215	5.441511	134	5.711674098	138	5.775233437	140	0.010329744	-0.858133548	normal	0.054078112	-0.764347315	normal	0.324022076	-0.621739754	normal	0.004829751	-0.756765702	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	Fumarylacetoacetate (FAA) hydrolase family	Fumarylacetoacetate hydrolase domain-containing protein 2B GN=FAHD2B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: fumarylacetoacetate hydrolase domain-containing protein 2A [Camelus ferus] 
ENSG00000144214(LYG1)	--	1.460251229	23	1.499066221	24	1.4310552	22	0.366143012	6	0.8045378	12	0.746758445	12	0.516541686	-1.729692783	normal	0.936054288	-0.936513071	normal	0.964545894	-0.806703784	normal	0.076688409	-1.220962999	normal	--	--	--	--	--	--	--	--	Lysozyme g-like protein 1 (Precursor) GN=LYG1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: lysozyme g-like protein 1 [Tupaia chinensis]
ENSG00000144218(AFF3)	--	0	0	0	0	0	0	0.196462864	6	0.009426699	0	0.009631917	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15195|0|hsa:3899|AFF3, LAF4, MLLT2-like; AF4/FMR2 family, member 3; K15195 AF4/FMR2 family member 3 (A)"	--	--	--	AF-4 proto-oncoprotein	AF4/FMR2 family member 3 GN=AFF3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: AF4/FMR2 family member 3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000144224(UBXN4)	--	41.707583	3034	41.682439	3036	39.39641592	2823	30.206059	2211	32.094373	2332	31.39808089	2272	0.432023245	-0.487064024	normal	0.792035511	-0.401801462	normal	0.917670656	-0.32136544	normal	0.007351537	-0.405167348	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	UBX domain	UBX domain-containing protein 4 GN=UBXN4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: UBX domain-containing protein 4 [Oryctolagus cuniculus]
ENSG00000144227(NXPH2)	--	0.111594	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16657|5.11736e-174|ptr:742551|NXPH2; neurexophilin 2; K16657 neurexophilin-2 (A)	--	--	--	Neurexophilin	Neurexophilin-2 (Precursor) GN=NXPH2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: neurexophilin-2 [Galeopterus variegatus]
ENSG00000144228(SPOPL)	--	5.87162	525	5.705761	511	5.503557038	481	4.100569032	371	3.854796177	345	3.501167	313	0.306722552	-0.529875484	normal	0.165863849	-0.58602827	normal	0.090828479	-0.625707813	normal	0.00277135	-0.581800219	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10523|0|ptr:460095|SPOPL; speckle-type POZ protein-like; K10523 speckle-type POZ protein (A)	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	BTB/POZ domain;; MATH domain	Speckle-type POZ protein-like GN=SPOPL OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: speckle-type POZ protein-like isoform 1 [Ceratotherium simum simum]
ENSG00000144230(GPR17)	--	0	0	0.0277715	1	0	0	0.170963	4	0.134976	4	0.082304	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08404|0|hsa:2840|GPR17; G protein-coupled receptor 17; K08404 G protein-coupled receptor 17 (A)	--	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Uracil nucleotide/cysteinyl leukotriene receptor GN=GPR17 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: uracil nucleotide/cysteinyl leukotriene receptor [Sorex araneus]
ENSG00000144233(AMMECR1L)	--	11.16614611	878	11.22087194	893	10.97269729	891	7.905314191	628	8.440002328	662	9.266514439	748	0.295934421	-0.513221146	normal	0.554412786	-0.452362144	normal	0.928352443	-0.260195954	normal	0.017530774	-0.406012947	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	AMMECR1	AMMECR1-like protein GN=AMMECR1L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: AMMECR1-like protein isoform X1 [Galeopterus variegatus] 
ENSG00000144278(GALNT13)	--	9.892982078	557	10.73901708	569	12.03535723	570	6.28991833	376	6.3573908	329	5.769464701	316	0.12008275	-0.595762578	normal	0.001972933	-0.808903188	normal	0.000532372	-0.856232817	normal	3.34E-05	-0.753883822	normal	--	--	--	"K00710|0|hsa:114805|GALNT13, GalNAc-T13; polypeptide N-acetylgalactosaminyltransferase 13 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 13 GN=GALNT13 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 13 isoform X1 [Sorex araneus]
ENSG00000144283(PKP4)	--	77.00155205	1451	55.62498604	1507	52.73099093	1588	16.77927966	1120	47.95313591	1025	32.25459167	1132	0.716880667	-0.403892688	normal	0.109190939	-0.576775585	normal	0.349694714	-0.496066105	normal	0.000939033	-0.493298054	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT repeat	Plakophilin-4 GN=PKP4 OS=Homo sapiens (Human) PE=1 SV=2	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: plakophilin-4 isoform X1 [Galeopterus variegatus]
ENSG00000144285(SCN1A)	--	0.036628621	4	0	0	0.018261638	1	0	0	0	0	0.007039652	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: voltage-gated sodium channel complex (GO:0001518);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated sodium channel activity (GO:0005248);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04833|0|hsa:6323|SCN1A, EIEE6, FEB3, FEB3A, FHM3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI; sodium channel, voltage-gated, type I, alpha subunit; K04833 voltage-gated sodium channel type I alpha (A)"	Dopaminergic synapse (ko04728)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Domain of unknown function (DUF3451);; Sodium ion transport-associated;; Polycystin cation channel	Sodium channel protein type 1 subunit alpha GN=SCN1A OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: sodium channel protein type 1 subunit alpha [Equus caballus]
ENSG00000144290(SLC4A10)	--	0.032129737	2	0.0316373	2	0.021567939	1	0.032345808	3	0.136483183	12	0.080640318	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13861|0|hsa:57282|SLC4A10, NBCn2, NCBE; solute carrier family 4, sodium bicarbonate transporter, member 10; K13861 solute carrier family 4 (sodium bicarbonate transporter), member 10 (A)"	--	[P]	Inorganic ion transport and metabolism	HCO3- transporter family;; Band 3 cytoplasmic domain	Sodium-driven chloride bicarbonate exchanger GN=SLC4A10 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium-driven chloride bicarbonate exchanger isoform 1 [Odobenus rosmarus divergens]
ENSG00000144306(SCRN3)	--	14.042323	457	15.22267368	409	11.03290601	375	11.927358	373	10.085366	352	9.908602	314	0.870235672	-0.32264764	normal	0.9319169	-0.237006305	normal	0.920204143	-0.263255676	normal	0.2574678	-0.278226981	normal	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: dipeptidase activity (GO:0016805);; 	K14358|0|pps:100989063|SCRN3; secernin 3; K14358 secernin (A)	--	--	--	Peptidase family C69	Secernin-3 GN=SCRN3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: secernin-3 [Vicugna pacos]
ENSG00000144320(LNPK)	--	9.923974946	789	10.76483257	936	12.35993473	905	8.21605641	728	6.212427675	527	7.010764217	560	0.965866212	-0.146621753	normal	0.000253786	-0.848279205	normal	0.009155174	-0.699282342	normal	0.00136381	-0.55717129	normal	[R]	General function prediction only	--	--	--	[S]	Function unknown	Predicted integral membrane metal-binding protein (DUF2296)	Protein lunapark GN=LNP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein lunapark isoformX1 [Equus caballus] 
ENSG00000144331(ZNF385B)	--	0.201160655	12	0	0	0.08508733	4	0.42443245	7	0.196892942	11	0.197034661	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; U1 zinc finger;; A-kinase anchoring protein 95 (AKAP95)	Zinc finger protein 385B GN=ZNF385B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 385B isoform X2 [Equus caballus]
ENSG00000144339(TMEFF2)	--	1.566259192	71	1.431407403	65	1.70622619	78	0.075416428	4	0.255277491	14	0.144854853	7	4.08E-12	-3.737899747	down	2.31E-05	-2.120348168	down	3.24E-11	-3.23103513	down	1.55E-10	-3.116920059	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Human growth factor-like EGF	Tomoregulin-2 (Precursor) GN=TMEFF2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tomoregulin-2 [Camelus ferus] 
ENSG00000144354(CDCA7)	--	32.91211551	1444	32.48866989	1448	36.22247907	1569	20.95706195	924	21.77174739	945	14.14646303	630	0.011056378	-0.674033544	normal	0.032629015	-0.636272686	normal	1.60E-12	-1.322630041	down	4.59E-09	-0.858031718	normal	--	--	--	--	--	--	--	Zinc-finger domain of monoamine-oxidase A repressor R1	Cell division cycle-associated protein 7 GN=CDCA7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cell division cycle-associated protein 7 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000144355(DLX1)	--	1.92723458	66	0.788330673	38	0.631573731	27	1.016895118	47	1.095018182	52	0.624768159	24	0.918567028	-0.506591102	normal	0.955947712	0.416855063	normal	0.985362064	-0.168217336	normal	0.931804253	-0.114497371	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09314|1.64947e-151|fca:101091802|DLX1; distal-less homeobox 1; K09314 homeobox protein DLX1/4/6 (A)	--	[K]	Transcription	Homeobox domain	Homeobox protein DLX-1 GN=DLX1 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: homeobox protein DLX-1 [Ailuropoda melanoleuca]
ENSG00000144357(UBR3)	--	8.72101869	1157	11.08122393	1408	9.845461708	1249	6.10407471	812	6.564900922	856	6.935591959	920	0.187419663	-0.540807233	normal	0.002839475	-0.738362974	normal	0.549008199	-0.44872355	normal	9.80E-05	-0.580363675	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K11978|0|hsa:130507|UBR3, ZNF650; ubiquitin protein ligase E3 component n-recognin 3 (putative) (EC:6.3.2.-); K11978 E3 ubiquitin-protein ligase UBR3 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Putative zinc finger in N-recognin (UBR box)	E3 ubiquitin-protein ligase UBR3 GN=UBR3 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase UBR3 [Pteropus alecto]
ENSG00000144362(PHOSPHO2)	--	14.6944123	851	12.79957895	776	15.21788277	871	9.27622964	538	7.855501637	466	7.791598318	430	0.011616248	-0.690801641	normal	0.003690837	-0.755232255	normal	1.24E-06	-1.024043533	down	2.69E-07	-0.822479814	normal	--	--	Molecular Function: phosphatase activity (GO:0016791);; 	"K13248|1.10636e-179|hsa:493911|PHOSPHO2; phosphatase, orphan 2 (EC:3.1.3.74); K13248 pyridoxal phosphate phosphatase PHOSPHO2 [EC:3.1.3.74] (A)"	Vitamin B6 metabolism (ko00750)	[R]	General function prediction only	Putative Phosphatase;; haloacid dehalogenase-like hydrolase;; Haloacid dehalogenase-like hydrolase	Pyridoxal phosphate phosphatase PHOSPHO2 GN=PHOSPHO2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: pyridoxal phosphate phosphatase PHOSPHO2 isoform X1 [Mustela putorius furo] 
ENSG00000144366(GULP1)	--	30.40975667	1211	32.297388	1436	28.9423741	1224	21.63821687	916	21.12247447	916	38.6547257	1642	0.608727201	-0.432977644	normal	0.015489483	-0.669172532	normal	0.688158944	0.415114781	normal	0.762955092	-0.175709156	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Phosphotyrosine interaction domain (PTB/PID);; Phosphotyrosine-binding domain;; Phosphotyrosine interaction domain (PTB/PID)	PTB domain-containing engulfment adapter protein 1 GN=GULP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: PTB domain-containing engulfment adapter protein 1 isoform X1 [Vicugna pacos]
ENSG00000144369(FAM171B)	--	5.810965632	535	6.683007	628	6.070452564	563	2.539541009	242	2.837612687	270	2.645835651	252	1.16E-07	-1.170229236	down	9.43E-09	-1.234558192	down	1.17E-07	-1.163204911	down	2.10E-11	-1.196899038	down	--	--	--	--	--	--	--	Uncharacterised protein family UPF0560	Protein FAM171B (Precursor) GN=FAM171B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM171B [Equus caballus] 
ENSG00000144381(HSPD1)	--	393.439243	18152	415.7084001	19637	453.8774433	20970	338.9935156	15654	291.5981178	13362	260.4224053	11937	0.991440485	-0.244407125	normal	0.288261453	-0.576810927	normal	0.000258729	-0.821098451	normal	0.001248416	-0.542699572	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K04077|0|hsa:3329|HSPD1, CPN60, GROEL, HLD4, HSP-60, HSP60, HSP65, HuCHA60, SPG13; heat shock 60kDa protein 1 (chaperonin); K04077 chaperonin GroEL (A)"	RNA degradation (ko03018);; Type I diabetes mellitus (ko04940);; Legionellosis (ko05134);; Tuberculosis (ko05152)	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	"60 kDa heat shock protein, mitochondrial (Precursor) GN=HSPD1 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: 60 kDa heat shock protein, mitochondrial isoform X1 [Tupaia chinensis] "
ENSG00000144395(CCDC150)	--	2.242697028	174	1.888631558	148	1.889203632	144	1.128753993	93	1.527846959	125	1.240423281	97	0.014224187	-0.923274631	normal	0.939460291	-0.262176675	normal	0.65172291	-0.570950105	normal	0.083189181	-0.586064836	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 150 GN=CCDC150 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 150 isoform X1 [Tupaia chinensis]
ENSG00000144401(METTL21A)	--	16.9378779	762	17.085865	782	17.58935251	782	10.6630328	507	7.637635721	439	7.216444611	472	0.060747301	-0.617100484	normal	0.000329207	-0.852142737	normal	0.004886252	-0.734824235	normal	7.35E-06	-0.735439922	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[A]	RNA processing and modification	Putative methyltransferase	Protein N-lysine methyltransferase METTL21A GN=METTL21A OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: protein N-lysine methyltransferase METTL21A [Galeopterus variegatus] 
ENSG00000144406(UNC80)	--	0.026811102	1	0	0	0	0	0	0	0.026095104	0	0.003578734	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein unc-80 homolog GN=UNC80 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein unc-80 homolog isoform X1 [Pteropus alecto]
ENSG00000144410(CPO)	--	0	0	0	0	0.251683	4	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[S]	Function unknown	Zinc carboxypeptidase	Carboxypeptidase O (Precursor) GN=CPO OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: carboxypeptidase O [Camelus ferus] 
ENSG00000144426(NBEAL1)	--	4.405788332	1120	4.668781746	1183	5.171561997	1241	3.0783237	781	2.432666062	622	2.84965651	724	0.162708741	-0.550027511	normal	8.97E-06	-0.947190161	normal	0.000729167	-0.784465919	normal	2.68E-07	-0.757956039	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; PH domain associated with Beige/BEACH;; WD domain, G-beta repeat;; Concanavalin A-like lectin/glucanases superfamily"	Neurobeachin-like protein 1 GN=NBEAL1 OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: neurobeachin-like protein 1 [Galeopterus variegatus]
ENSG00000144445(KANSL1L)	--	1.959840575	162	2.406529962	183	2.321975403	177	1.911310863	144	1.22737982	102	2.224548529	149	0.952879618	-0.198756354	normal	0.032983271	-0.855097087	normal	0.938368181	-0.254356777	normal	0.214389274	-0.423412948	normal	--	--	--	--	--	--	--	PEHE domain	KAT8 regulatory NSL complex subunit 1-like protein GN=KANSL1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: KAT8 regulatory NSL complex subunit 1-like protein isoform X1 [Leptonychotes weddellii]
ENSG00000144451(SPAG16)	--	12.77202571	235	15.72119991	300	12.86942321	239	9.958727813	185	10.38172101	189	7.807402293	146	0.851832319	-0.373210057	normal	0.0908912	-0.683620525	normal	0.096603937	-0.713498338	normal	0.022309339	-0.595877208	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	Sperm-associated antigen 16 protein GN=SPAG16 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: sperm-associated antigen 16 protein [Odobenus rosmarus divergens]
ENSG00000144452(ABCA12)	--	0.4724951	79	0.961644062	71	1.65518621	92	2.138954319	266	1.480638269	256	2.51372907	437	4.85E-11	1.701571697	up	8.04E-12	1.807203645	up	0	2.221179304	up	0.000183933	1.967222266	up	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05646|0|pps:100971773|ABCA12; ATP-binding cassette, sub-family A (ABC1), member 12; K05646 ATP-binding cassette, subfamily A (ABC1), member 12 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC transporter;; ABC-2 family transporter protein;; AAA domain	ATP-binding cassette sub-family A member 12 GN=ABCA12 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family A member 12-like isoform X2 [Tupaia chinensis]
ENSG00000144455(SUMF1)	--	22.25808389	769	23.84683835	783	22.43153332	750	24.47785847	803	23.95105987	779	27.28249562	882	0.976332479	0.031522493	normal	0.975806718	-0.028759848	normal	0.94589123	0.225177503	normal	0.775160352	0.077120782	normal	[S]	Function unknown	--	K13444|0|pps:100986538|SUMF1; sulfatase modifying factor 1; K13444 sulfatase modifying factor 1 (A)	Lysosome (ko04142)	--	--	Sulfatase-modifying factor enzyme 1	Sulfatase-modifying factor 1 (Precursor) GN=SUMF1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: sulfatase-modifying factor 1 isoform X1 [Tupaia chinensis]
ENSG00000144460(NYAP2)	--	0.028830025	2	0	0	0.042586824	2	0.07229911	5	0.139752517	9	0.156648535	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 GN=NYAP2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 [Ceratotherium simum simum]
ENSG00000144468(RHBDD1)	--	8.437505	646	6.567560025	559	9.729922445	569	4.590831264	368	3.821040744	349	5.63974339	397	0.000538423	-0.839976271	normal	0.021448114	-0.698632408	normal	0.309049002	-0.52589847	normal	0.000117713	-0.692318135	normal	[R]	General function prediction only	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09651|0|hsa:84236|RHBDD1, RRP4; rhomboid domain containing 1 (EC:3.4.21.105); K09651 rhomboid domain-containing protein 1 [EC:3.4.21.-] (A)"	--	[S]	Function unknown	Rhomboid family	Rhomboid-related protein 4 GN=RHBDD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rhomboid-related protein 4 isoform X1 [Galeopterus variegatus]
ENSG00000144476(ACKR3)	--	0.702922	15	0.609015446	11	0.386928805	10	0.402948466	10	0.579844	17	0.5592614	19	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04304|0|hsa:57007|ACKR3, CMKOR1, CXC-R7, CXCR-7, CXCR7, GPR159, RDC-1, RDC1; atypical chemokine receptor 3; K04304 C-X-C chemokine receptor type 7 (A)"	Cytokine-cytokine receptor interaction (ko04060)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Atypical chemokine receptor 3 GN=ACKR3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: atypical chemokine receptor 3 [Galeopterus variegatus]
ENSG00000144481(TRPM8)	--	0.216483655	7	0.082790807	4	0.043690384	1	0.156340245	4	0.378985588	12	0.37076752	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04983|0|hsa:79054|TRPM8, LTRPC6, TRPP8; transient receptor potential cation channel, subfamily M, member 8; K04983 transient receptor potential cation channel subfamily M member 8 (A)"	Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein	Transient receptor potential cation channel subfamily M member 8 GN=TRPM8 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily M member 8 [Felis catus]
ENSG00000144485(HES6)	--	14.27450215	308	12.01436081	251	12.75736698	294	9.012109957	166	7.424503126	153	6.802871055	152	0.001239148	-0.916248552	normal	0.071157655	-0.729889556	normal	0.000768672	-0.953093364	normal	0.000229189	-0.878161422	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K09087|5.98389e-119|mcf:102139892|HES6; hairy and enhancer of split 6 (Drosophila); K09087 hairy and enhancer of split 2/6/7 (A)	--	[K]	Transcription	Hairy Orange;; Helix-loop-helix DNA-binding domain	Transcription cofactor HES-6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription cofactor HES-6 [Odobenus rosmarus divergens]
ENSG00000144488(ESPNL)	--	0.310025084	23	0.277099033	24	0.235133472	19	0.029243388	2	0.014340486	0	0.058195564	4	0.018175146	-2.817726917	normal	0.000251742	-4.086503415	down	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Espin-like protein GN=ESPNL OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: espin-like protein [Eptesicus fuscus]
ENSG00000144504(ANKMY1)	--	5.5287042	278	12.57296982	286	4.627001036	272	3.1094643	157	3.6388073	173	5.564400411	262	0.006801801	-0.848819855	normal	0.04273082	-0.741572357	normal	0.965782517	-0.061980139	normal	0.050859862	-0.517627623	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies);; MORN repeat;; Ankyrin repeats (many copies);; MYND finger	Ankyrin repeat and MYND domain-containing protein 1 GN=ANKMY1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and MYND domain-containing protein 1 [Galeopterus variegatus]
ENSG00000144524(COPS7B)	--	17.52418069	726	15.61135342	716	17.80720693	744	12.77434079	551	13.78130238	548	11.04682417	452	0.635130152	-0.427706711	normal	0.711995495	-0.406226291	normal	0.006578249	-0.725359698	normal	0.002960812	-0.516760352	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12180|0|mcf:102135681|COPS7B; COP9 signalosome subunit 7B; K12180 COP9 signalosome complex subunit 7 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PCI domain	COP9 signalosome complex subunit 7b GN=COPS7B OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	hypothetical protein PANDA_005713 [Ailuropoda melanoleuca]
ENSG00000144535(DIS3L2)	--	10.08730691	912	14.67674851	953	12.39152579	1019	9.306576998	686	9.60642701	791	7.881885059	834	0.579634715	-0.440797963	normal	0.9092364	-0.289719607	normal	0.903230694	-0.296838397	normal	0.049706628	-0.339979447	normal	[K]	Transcription	--	K18758|0|pps:100991517|DIS3L2; DIS3 like 3'-5' exoribonuclease 2; K18758 DIS3-like exonuclease 2 [EC:3.1.13.-] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	RNB domain	DIS3-like exonuclease 2 {ECO:0000255|HAMAP-Rule:MF_03045} OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: DIS3-like exonuclease 2 [Ceratotherium simum simum]
ENSG00000144550(CPNE9)	--	0.07461835	3	0	0	0.165977252	1	0	0	0.096449185	3	0.050366173	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-9 GN=CPNE9 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: copine-9 isoform X1 [Mustela putorius furo] 
ENSG00000144554(FANCD2)	--	25.9349344	1269	11.663633	1153	14.35773	1400	9.095330422	904	8.780965498	852	8.5612076	855	0.255237142	-0.519380597	normal	0.532384016	-0.457193241	normal	0.003758223	-0.718718193	normal	0.000130477	-0.570813024	normal	--	--	Biological Process: DNA repair (GO:0006281);; 	"K10891|0|hsa:2177|FANCD2, FA-D2, FA4, FACD, FAD, FAD2, FANCD; Fanconi anemia, complementation group D2; K10891 fanconi anemia group D2 protein (A)"	Fanconi anemia pathway (ko03460)	[S]	Function unknown	Fanconi anaemia protein FancD2 nuclease	Fanconi anemia group D2 protein GN=FANCD2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Fanconi anemia group D2 protein isoform X6 [Canis lupus familiaris]
ENSG00000144559(TAMM41)	--	14.9415746	163	12.70068469	157	14.10197	181	15.333126	200	11.689786	174	11.73559028	167	0.932999067	0.262062738	normal	0.960447275	0.125745315	normal	0.961681259	-0.123359688	normal	0.85524416	0.08928054	normal	--	--	Molecular Function: phosphatidate cytidylyltransferase activity (GO:0004605);; Biological Process: cardiolipin biosynthetic process (GO:0032049);; 	"K17807|0|ptr:460174|TAMM41; TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); K17807 mitochondrial translocator assembly and maintenance protein 41 (A)"	--	[S]	Function unknown	Mitochondrial matrix Mmp37	"Phosphatidate cytidylyltransferase, mitochondrial (Precursor) GN=TAMM41 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: phosphatidate cytidylyltransferase, mitochondrial [Ailuropoda melanoleuca]"
ENSG00000144560(VGLL4)	--	16.47428447	771	18.38467926	1012	16.9673447	745	23.8875593	1137	25.370419	1198	25.80331127	1274	0.228794603	0.528724752	normal	0.95323788	0.22168729	normal	0.001235412	0.764560756	normal	0.003008319	0.492391828	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	Transcription cofactor vestigial-like protein 4	Transcription cofactor vestigial-like protein 4 GN=VGLL4 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: transcription cofactor vestigial-like protein 4 [Galeopterus variegatus]
ENSG00000144566(RAB5A)	--	28.25282422	1135	27.92121344	1130	28.43413701	1114	32.33775217	1293	29.04983979	1196	30.81847505	1266	0.971240774	0.156998502	normal	0.979549766	0.060389497	normal	0.96749135	0.176012452	normal	0.542945218	0.130904409	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07887|1.70051e-160|ggo:101144180|RAB5A; ras-related protein Rab-5A; K07887 Ras-related protein Rab-5A (A)	Ras signaling pathway (ko04014);; Endocytosis (ko04144);; Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Amoebiasis (ko05146);; Tuberculosis (ko05152)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-5A GN=RAB5A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	ras-related protein Rab-5A [Canis lupus familiaris] 
ENSG00000144567(FAM134A)	--	30.583686	1691	36.7357765	1991	27.676261	1691	21.112791	1140	20.311583	1104	23.75215041	1272	0.059199613	-0.599007485	normal	4.80E-05	-0.871277331	normal	0.677875306	-0.418636243	normal	8.06E-06	-0.632861574	normal	--	--	--	--	--	--	--	Reticulon	Protein FAM134A GN=FAM134A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM134A [Oryctolagus cuniculus]
ENSG00000144579(CTDSP1)	--	29.5540936	1422	30.64020859	1497	29.80569716	1441	21.23932947	1010	20.66435559	988	21.41197531	1034	0.237996605	-0.523723324	normal	0.045856676	-0.620140758	normal	0.389105972	-0.486519976	normal	0.000217516	-0.545220747	normal	[K]	Transcription	--	"K15731|2.0722e-173|bta:516199|CTDSP1; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (EC:3.1.3.16); K15731 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16] (A)"	--	[K]	Transcription	NLI interacting factor-like phosphatase	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 GN=CTDSP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 [Bos taurus] 
ENSG00000144580(CNOT9)	--	24.47204697	1226	27.99843675	1403	24.54434552	1176	18.6704378	957	18.2324002	945	18.62587094	894	0.756186336	-0.387648913	normal	0.084570495	-0.590774011	normal	0.711562136	-0.403236098	normal	0.002517794	-0.466137501	normal	[R]	General function prediction only	--	"K12606|0|hsa:9125|RQCD1, CNOT9, CT129, RCD-1, RCD1; RCD1 required for cell differentiation1 homolog (S. pombe); K12606 CCR4-NOT transcription complex subunit 9 (A)"	RNA degradation (ko03018)	[R]	General function prediction only	"Cell differentiation family, Rcd1-like"	Cell differentiation protein RCD1 homolog GN=RQCD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cell differentiation protein RCD1 homolog isoform X1 [Condylura cristata]
ENSG00000144583(MARCH4)	--	5.13206	481	5.01557	472	7.77267	729	9.86806	908	5.469518	501	5.32553	496	7.99E-05	0.883736353	normal	0.96888662	0.064396908	normal	0.163911346	-0.562446639	normal	0.843370735	0.157096671	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10659|0|hsa:57574|MARCH4, MARCH-IV, RNF174; membrane-associated ring finger (C3HC4) 4, E3 ubiquitin protein ligase; K10659 E3 ubiquitin-protein ligase MARCH4/9/11 [EC:6.3.2.19] (A)"	--	--	--	RING-variant domain	E3 ubiquitin-protein ligase MARCH4 (Precursor) GN=MARCH4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: E3 ubiquitin-protein ligase MARCH4 [Loxodonta africana]
ENSG00000144589(STK11IP)	--	7.278237633	521	8.945957175	624	6.9720359	511	3.855263	267	4.87662882	345	4.630303261	331	2.20E-05	-0.991112407	normal	0.000332196	-0.87348561	normal	0.074705571	-0.632439292	normal	4.85E-06	-0.833101307	normal	--	--	--	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat	Serine/threonine-protein kinase 11-interacting protein GN=STK11IP OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: serine/threonine-protein kinase 11-interacting protein [Galeopterus variegatus]
ENSG00000144591(GMPPA)	--	25.85753668	693	23.6923772	627	27.81767757	724	13.91534742	386	17.7797075	461	20.08976987	523	0.000193797	-0.872455394	normal	0.535926859	-0.463815006	normal	0.459685552	-0.476294325	normal	0.000575877	-0.597291977	normal	[MJ]	"Cell wall/membrane/envelope biogenesis;; Translation, ribosomal structure and biogenesis"	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	K00966|0|ptr:459966|GMPPA; GDP-mannose pyrophosphorylase A; K00966 mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] (A)	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[GMO]	"Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	Nucleotidyl transferase;; MobA-like NTP transferase domain;; Bacterial transferase hexapeptide (six repeats)	Mannose-1-phosphate guanyltransferase alpha GN=GMPPA OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: mannose-1-phosphate guanyltransferase alpha isoform X5 [Balaenoptera acutorostrata scammoni]
ENSG00000144596(GRIP2)	--	0.728677448	60	0.409515958	63	0.314959939	54	0.275865955	40	0.314937772	48	0.40624932	62	0.894672594	-0.596940144	normal	0.946899148	-0.402635572	normal	0.972366645	0.186148796	normal	0.696661854	-0.258895603	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Tricorn protease PDZ domain;; GRASP55/65 PDZ-like domain	Glutamate receptor-interacting protein 2 GN=GRIP2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: glutamate receptor-interacting protein 2 [Pteropus alecto]
ENSG00000144597(EAF1)	--	10.6735	870	10.5718	866	11.4329	925	10.161	831	11.0654	898	9.72775	793	0.973691856	-0.0968242	normal	0.977222089	0.030868926	normal	0.944849257	-0.230017362	normal	0.689714633	-0.098556054	normal	--	--	--	K15186|2.02697e-130|cjc:100415188|EAF1; ELL associated factor 1; K15186 ELL-associated factor (A)	--	[K]	Transcription	RNA polymerase II transcription elongation factor	ELL-associated factor 1 GN=EAF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ELL-associated factor 1 [Felis catus]
ENSG00000144619(CNTN4)	--	0	0	0	0	0	0	0.020399144	1	0.01413596	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06762|0|hsa:152330|CNTN4, AXCAM, BIG-2; contactin 4; K06762 contactin 4 (A)"	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Zona-pellucida-binding protein (Sp38);; CD47 immunoglobulin-like domain;; Immunoglobulin C2-set domain	Contactin-4 (Precursor) GN=CNTN4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: contactin-4 isoformX1 [Canis lupus familiaris] 
ENSG00000144635(DYNC1LI1)	--	19.49432162	828	20.11233679	859	20.21684987	848	16.81700511	732	19.79866755	851	17.31599713	741	0.951210841	-0.208208133	normal	0.976746519	-0.034863891	normal	0.953594672	-0.202495532	normal	0.517901781	-0.146449359	normal	--	--	--	"K10416|0|hsa:51143|DYNC1LI1, DNCLI1, LIC1; dynein, cytoplasmic 1, light intermediate chain 1; K10416 dynein light intermediate chain 1, cytosolic (A)"	Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Salmonella infection (ko05132)	[N]	Cell motility	Dynein light intermediate chain (DLIC);; Miro-like protein;; ABC transporter	Cytoplasmic dynein 1 light intermediate chain 1 GN=DYNC1LI1 OS=Homo sapiens (Human) PE=1 SV=3	N	Cell motility	PREDICTED: cytoplasmic dynein 1 light intermediate chain 1 isoform X1 [Leptonychotes weddellii]
ENSG00000144642(RBMS3)	--	0.575658339	28	0.608942773	26	0.319128218	28	3.025699212	252	3.084351195	245	1.630157015	134	0	3.071686831	up	0	3.142739592	up	1.57E-10	2.191003253	up	2.01E-07	2.921248427	up	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"RNA-binding motif, single-stranded-interacting protein 3 GN=RBMS3 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: RNA-binding motif, single-stranded-interacting protein 3 isoform X4 [Mustela putorius furo]"
ENSG00000144645(OSBPL10)	--	3.3956925	346	3.264584285	349	3.347814864	345	5.530622537	536	5.322778171	493	4.434717765	471	0.124139647	0.598478199	normal	0.531504856	0.475193772	normal	0.643184033	0.439185253	normal	0.011428352	0.506771954	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Oxysterol-binding protein;; Pleckstrin homology domain;; PH domain	Oxysterol-binding protein-related protein 10 GN=OSBPL10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein-related protein 10 [Felis catus]
ENSG00000144647(POMGNT2)	--	11.16091113	533	8.0042249	388	10.04294262	490	6.533418	307	7.360422	349	5.99015519	287	0.001337847	-0.823558519	normal	0.951998654	-0.173542561	normal	0.004932932	-0.776851674	normal	0.003975948	-0.602508	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K18207|0|hsa:84892|POMGNT2, AGO61, C3orf39, GTDC2, MDDGA8; protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) (EC:2.4.1.255); K18207 protein O-mannose beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.312] (A)"	--	[S]	Function unknown	Protein of unknown function (DUF563)	"Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2 {ECO:0000303|PubMed:23929950} GN=POMGNT2 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	PREDICTED: glycosyltransferase-like domain-containing protein 2 isoform X1 [Equus caballus] 
ENSG00000144648(ACKR2)	--	0.305270817	7	0.0166402	1	0.071744197	2	0	0	0.023700212	0	0.02394579	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04187|0|hsa:1238|ACKR2, CCBP2, CCR10, CCR9, CMKBR9, D6, hD6; atypical chemokine receptor 2; K04187 chemokine binding protein 2 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Atypical chemokine receptor 2 GN=ACKR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: atypical chemokine receptor 2 [Loxodonta africana]
ENSG00000144655(CSRNP1)	--	5.02825	285	4.106263721	246	4.503336	270	9.10162	522	8.777979	507	6.89864	393	0.001093909	0.838866884	normal	1.88E-05	1.017453239	up	0.377362862	0.530800284	normal	3.34E-05	0.806143766	normal	--	--	--	"K17494|0|hsa:64651|CSRNP1, AXUD1, CSRNP-1, FAM130B, TAIP-3, URAX1; cysteine-serine-rich nuclear protein 1; K17494 cysteine/serine-rich nuclear protein (A)"	--	[R]	General function prediction only	--	Cysteine/serine-rich nuclear protein 1 GN=CSRNP1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: cysteine/serine-rich nuclear protein 1 [Ceratotherium simum simum]
ENSG00000144659(SLC25A38)	--	20.66492091	693	21.433357	744	18.03915036	629	20.37048872	705	22.2215764	747	25.73298928	888	0.975362415	-0.006051058	normal	0.975485123	-0.015589313	normal	0.395764066	0.488215597	normal	0.488339402	0.158920731	normal	--	--	--	"K15118|0|ptr:460283|SLC25A38; solute carrier family 25, member 38; K15118 solute carrier family 25, member 38 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 38 {ECO:0000255|HAMAP-Rule:MF_03064} OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 38 isoform X1 [Myotis brandtii] 
ENSG00000144668(ITGA9)	--	0.025757676	4	0.025015919	4	0.056885459	8	0.023491481	3	0	0	0.023544562	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06585|0|hsa:3680|ITGA9, ALPHA-RLC, ITGA4L, RLC; integrin, alpha 9; K06585 integrin alpha 9 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Regulation of actin cytoskeleton (ko04810);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Integrin alpha-9 (Precursor) GN=ITGA9 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin alpha-9 [Ceratotherium simum simum]
ENSG00000144671(SLC22A14)	--	0.032306008	1	0	0	0.094533767	2	0.209388012	1	0.03157035	0	0.0261194	1	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08210|0|hsa:9389|SLC22A14, OCTL2, OCTL4, ORCTL4; solute carrier family 22, member 14; K08210 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 14 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 14 GN=SLC22A14 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: solute carrier family 22 member 14 [Ceratotherium simum simum]
ENSG00000144674(GOLGA4)	--	20.386119	3808	27.6132391	5169	26.96706388	5006	29.634108	5514	28.5671521	5418	31.68213269	5849	0.428538983	0.503063997	normal	0.993209467	0.046435364	normal	0.98373007	0.216179782	normal	0.180926608	0.242267158	normal	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	GRIP domain	Golgin subfamily A member 4 GN=GOLGA4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: golgin subfamily A member 4 isoform X3 [Galeopterus variegatus]
ENSG00000144677(CTDSPL)	--	15.609363	927	13.99571473	829	15.956474	971	9.332303082	635	9.132625865	595	10.02110236	631	0.113330367	-0.575484939	normal	0.376620296	-0.498829545	normal	0.040234409	-0.628898054	normal	0.000362145	-0.572265667	normal	[K]	Transcription	--	"K15731|0|hsa:10217|CTDSPL, C3orf8, HYA22, PSR1, RBSP3, SCP3; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like (EC:3.1.3.16); K15731 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16] (A)"	--	[K]	Transcription	NLI interacting factor-like phosphatase	CTD small phosphatase-like protein GN=CTDSPL OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CTD small phosphatase-like protein isoform X2 [Sus scrofa]
ENSG00000144681(STAC)	--	2.801502914	173	2.630718703	167	3.108065362	159	3.47187736	207	3.06890613	199	2.894892492	181	0.943146768	0.2261882	normal	0.941362207	0.229587238	normal	0.955046747	0.177091821	normal	0.579236144	0.212631992	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	SH3 and cysteine-rich domain-containing protein GN=STAC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH3 and cysteine-rich domain-containing protein isoform 1 [Trichechus manatus latirostris]
ENSG00000144711(IQSEC1)	--	11.42485249	1655	10.784002	1570	10.45841064	1530	10.495981	1513	10.14416453	1489	7.838337852	1143	0.974912873	-0.160095973	normal	0.98074972	-0.097750663	normal	0.636030773	-0.42850586	normal	0.222801065	-0.220100153	normal	--	--	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K12495|0|hsa:9922|IQSEC1, ARF-GEP100, ARFGEP100, BRAG2, GEP100; IQ motif and Sec7 domain 1; K12495 IQ motif and SEC7 domain-containing protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain	IQ motif and SEC7 domain-containing protein 1 GN=IQSEC1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: IQ motif and SEC7 domain-containing protein 1 isoform 2 [Trichechus manatus latirostris]
ENSG00000144712(CAND2)	--	0.963963	84	1.5340972	136	1.11247	99	0.4761089	41	0.916951	79	0.432982215	38	0.104614079	-1.037837794	normal	0.178570853	-0.793387156	normal	0.001384971	-1.355068981	down	0.033178484	-1.034904967	normal	--	--	--	--	--	[R]	General function prediction only	TATA-binding protein interacting (TIP20);; HEAT repeats;; HEAT repeat;; HEAT-like repeat;; non-SMC mitotic condensation complex subunit 1;; Adaptin N terminal region	Cullin-associated NEDD8-dissociated protein 2 GN=CAND2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: cullin-associated NEDD8-dissociated protein 2 isoform X1 [Eptesicus fuscus]
ENSG00000144713(RPL32)	--	552.1341646	7967	513.7638609	7592	539.2893034	7719	620.8294371	8935	591.9769498	8438	565.158891	8003	0.993717647	0.134574376	normal	0.9933784	0.130969783	normal	0.995231978	0.043827076	normal	0.668074155	0.102970657	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02912|7.88029e-80|umr:103669537|RPL32; ribosomal protein L32; K02912 large subunit ribosomal protein L32e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L32	60S ribosomal protein L32 GN=RPL32 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L32 [Ochotona princeps]
ENSG00000144724(PTPRG)	--	7.389340461	1144	7.449932503	1213	7.87234844	1231	4.802356131	770	5.122376546	750	6.491161344	973	0.063330246	-0.600998013	normal	0.005881734	-0.713900146	normal	0.844418864	-0.34712967	normal	0.000315571	-0.545741636	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K16667|0|hsa:5793|PTPRG, HPTPG, PTPG, R-PTP-GAMMA, RPTPG; protein tyrosine phosphatase, receptor type, G (EC:3.1.3.48); K16667 receptor-type tyrosine-protein phosphatase gamma [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase;; Eukaryotic-type carbonic anhydrase;; Fibronectin type III domain	Receptor-type tyrosine-protein phosphatase gamma (Precursor) GN=PTPRG OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase gamma isoform 1 [Ceratotherium simum simum]
ENSG00000144730(IL17RD)	--	1.943240653	279	0.980302492	155	1.50780622	228	0.862422911	137	0.80785781	114	0.590457937	88	0.000132107	-1.048499335	down	0.810175626	-0.459412382	normal	6.99E-07	-1.366607827	down	0.02166257	-0.987842304	normal	--	--	--	"K05167|0|hsa:54756|IL17RD, HH18, IL-17RD, IL17RLM, SEF; interleukin 17 receptor D; K05167 interleukin 17 receptor D (A)"	--	--	--	SEFIR domain	Interleukin-17 receptor D (Precursor) GN=IL17RD OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: interleukin-17 receptor D isoform X1 [Galeopterus variegatus]
ENSG00000144736(SHQ1)	--	7.600369528	402	8.788479149	473	10.51163731	475	10.72288413	544	10.62898922	551	9.320769802	484	0.723698279	0.404246422	normal	0.948168434	0.19819801	normal	0.971274385	0.01872902	normal	0.398456834	0.204669853	normal	--	--	--	"K14764|0|hsa:55164|SHQ1, Shq1p; SHQ1, H/ACA ribonucleoprotein assembly factor; K14764 protein SHQ1 (A)"	--	[S]	Function unknown	SHQ1 protein	Protein SHQ1 homolog GN=SHQ1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein SHQ1 homolog [Ceratotherium simum simum]
ENSG00000144741(SLC25A26)	--	13.5095857	263	11.95474579	230	14.01262	261	12.550499	246	13.8378023	274	13.20731301	243	0.960069809	-0.126472574	normal	0.936716473	0.229730121	normal	0.961913675	-0.110719904	normal	0.999834061	-0.003913538	normal	--	--	--	"K15111|8.84361e-177|pps:100974512|SLC25A26; solute carrier family 25 (S-adenosylmethionine carrier), member 26; K15111 solute carrier family 25 (mitochondrial S-adenosylmethionine transporter), member 26 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	S-adenosylmethionine mitochondrial carrier protein GN=SLC25A26 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: S-adenosylmethionine mitochondrial carrier protein [Pteropus alecto]
ENSG00000144744(UBA3)-2	--	18.18329626	631	18.51643411	621	18.15483205	621	19.55242923	691	21.90305806	730	16.22838939	565	0.970173402	0.099980766	normal	0.947579287	0.211401399	normal	0.963129264	-0.14426537	normal	0.831761381	0.062814215	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000144746(ARL6IP5)	--	55.107977	1687	48.6061022	1483	59.13140364	1776	74.452093	2288	65.044377	1980	66.387898	2031	0.733422743	0.408474313	normal	0.773608823	0.39520541	normal	0.973615444	0.185119711	normal	0.039851684	0.327492715	normal	--	--	--	--	--	[ET]	Amino acid transport and metabolism;; Signal transduction mechanisms	PRA1 family protein	PRA1 family protein 3 GN=ARL6IP5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PRA1 family protein 3 [Equus caballus] 
ENSG00000144747(TMF1)	--	6.256198	820	7.843171	1020	7.803286	1000	7.53931	998	7.41636	976	7.98003	1050	0.934938686	0.252154847	normal	0.976256907	-0.084913939	normal	0.978454655	0.062006367	normal	0.790313523	0.069623458	normal	--	--	--	--	--	[K]	Transcription	TATA element modulatory factor 1 TATA binding;; TATA element modulatory factor 1 DNA binding	TATA element modulatory factor GN=TMF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: TATA element modulatory factor [Ursus maritimus]
ENSG00000144749(LRIG1)	--	3.226789238	327	2.426852227	253	2.606748103	265	1.313235702	132	1.863546586	188	1.527225524	156	5.17E-08	-1.329402463	down	0.732742284	-0.446721325	normal	0.033381775	-0.766965783	normal	0.000396329	-0.848677959	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Immunoglobulin I-set domain;; Leucine Rich repeats (2 copies);; Immunoglobulin domain;; Immunoglobulin domain;; Leucine Rich Repeat;; Immunoglobulin domain;; Leucine rich repeats (6 copies);; Immunoglobulin V-set domain;; Leucine Rich repeat;; CD80-like C2-set immunoglobulin domain;; Leucine rich repeat;; Leucine-rich repeat;; Leucine rich repeat C-terminal domain	Leucine-rich repeats and immunoglobulin-like domains protein 1 (Precursor) GN=LRIG1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeats and immunoglobulin-like domains protein 1 [Ceratotherium simum simum]
ENSG00000144791(LIMD1)	--	21.40567555	2653	27.42093296	3450	26.87694402	3220	12.6947408	1546	11.45641702	1347	15.93890995	1968	0.000194247	-0.809294585	normal	2.94E-14	-1.377269801	down	0.002961871	-0.718185992	normal	5.03E-06	-0.960012803	normal	--	--	--	K16682|0|hsa:8994|LIMD1; LIM domains containing 1; K16682 LIM domain-containing protein (A)	Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	LIM domain	LIM domain-containing protein 1 GN=LIMD1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LIM domain-containing protein 1 [Vicugna pacos]
ENSG00000144792(ZNF660)	--	2.523335935	228	2.301445911	189	1.832404868	165	2.193798749	217	2.186961908	204	2.273433728	256	0.962786329	-0.101470023	normal	0.962855432	0.08807792	normal	0.254884485	0.620783184	normal	0.585518535	0.197049382	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Transposase zinc-ribbon domain;; DNA directed RNA polymerase, 7 kDa subunit;; Transcription factor S-II (TFIIS);; C1-like domain"	Zinc finger protein 660 GN=ZNF660 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 660 [Oryctolagus cuniculus] 
ENSG00000144802(NFKBIZ)	--	5.333721024	360	6.497996494	438	4.853660688	325	20.31381168	1333	15.24053491	1013	20.67944563	1382	0	1.853376612	up	5.19E-09	1.185437203	up	0	2.074858554	up	8.94E-13	1.709444413	up	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14242|0|pps:100990070|NFKBIZ; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta; K14242 NF-kappa-B inhibitor zeta (A)"	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	NF-kappa-B inhibitor zeta GN=NFKBIZ OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: NF-kappa-B inhibitor zeta [Ceratotherium simum simum]
ENSG00000144810(COL8A1)	--	0.055205256	6	0	0	0.013696871	0	0.018373173	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Collagen triple helix repeat (20 copies);; C1q domain	Vastatin (Precursor) GN=COL8A1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	collagen VIII [Sus scrofa]
ENSG00000144815(NXPE3)	--	27.40170521	1680	26.75568053	1758	29.37783282	1793	27.43709415	1739	25.54220217	1751	22.69191911	1527	0.985271915	0.018947405	normal	0.985064579	-0.027159135	normal	0.955634453	-0.239747498	normal	0.727994514	-0.08173211	normal	--	--	--	--	--	--	--	Neurexophilin	NXPE family member 3 (Precursor) GN=NXPE3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: NXPE family member 3 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000144821(MYH15)	--	0.358838926	55	0.185539483	29	0.38607214	62	0.548011883	85	0.624503024	96	0.543335355	86	0.830713123	0.5839868	normal	5.29E-05	1.655464247	up	0.909705559	0.454328774	normal	0.045005936	0.850627687	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10352|0|hsa:22989|MYH15; myosin, heavy chain 15; K10352 myosin heavy chain (A)"	Tight junction (ko04530)	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; Myosin N-terminal SH3-like domain	Myosin-15 GN=MYH15 OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: myosin-15 [Galeopterus variegatus]
ENSG00000144824(PHLDB2)	--	20.62542007	2242	14.8222949	1696	20.47767794	2386	37.53334662	4254	30.13157401	3553	26.83597406	3219	1.15E-05	0.892750236	normal	7.44E-08	1.044817148	up	0.717346566	0.423495169	normal	0.000178308	0.780338524	normal	--	--	--	--	--	--	--	PH domain	Pleckstrin homology-like domain family B member 2 GN=PHLDB2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: pleckstrin homology-like domain family B member 2 isoform 1 [Ceratotherium simum simum]
ENSG00000144827(ABHD10)	--	16.67622093	608	14.29476992	523	16.031305	574	17.58407996	652	17.84685599	653	14.538166	532	0.972040745	0.069798039	normal	0.894936589	0.298072789	normal	0.966228668	-0.117594029	normal	0.762702123	0.085904155	normal	[R]	General function prediction only	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; 	K13702|0|ptr:743016|ABHD10; abhydrolase domain containing 10; K13702 abhydrolase domain-containing protein 10 [EC:3.1.1.93] (A)	--	--	--	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Prolyl oligopeptidase family	"Mycophenolic acid acyl-glucuronide esterase, mitochondrial (Precursor) GN=ABHD10 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: mycophenolic acid acyl-glucuronide esterase, mitochondrial [Galeopterus variegatus]"
ENSG00000144837(PLA1A)	--	0.343618755	8	0.501317995	14	0.04233574	0	0.827737847	18	1.305780082	33	1.532582397	43	--	--	--	0.748731268	1.133786112	normal	3.35E-09	4.875399368	up	--	--	--	--	--	--	K13618|0|pps:100969100|PLA1A; phospholipase A1 member A; K13618 phospholipase A1 member A [EC:3.1.1.-] (A)	Ras signaling pathway (ko04014)	--	--	Lipase	Phospholipase A1 member A (Precursor) GN=PLA1A OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: phospholipase A1 member A [Physeter catodon]
ENSG00000144840(RABL3)	--	10.962756	472	12.539053	471	8.111591109	388	11.46875	577	11.37268728	548	8.436574053	417	0.922713168	0.258191057	normal	0.948645793	0.196437106	normal	0.965593493	0.095340775	normal	0.49143767	0.189869289	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07933|1.06857e-163|ptr:460614|RABL3; RAB, member of RAS oncogene family-like 3; K07933 Rab-like protein 3 (A)"	--	--	--	Ras family;; Miro-like protein;; Gtr1/RagA G protein conserved region;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase	Rab-like protein 3 GN=RABL3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: RAB, member of RAS oncogene family-like 3 isoform X3 [Canis lupus familiaris] "
ENSG00000144843(ADPRH)	--	3.268281386	180	2.55097605	156	2.612793153	160	1.89174662	113	2.05027576	103	1.635058784	98	0.22467831	-0.694947321	normal	0.512062043	-0.612960482	normal	0.262645971	-0.706886961	normal	0.033575044	-0.681266108	normal	--	--	--	"K01245|0|hsa:141|ADPRH, ARH1; ADP-ribosylarginine hydrolase (EC:3.2.2.19); K01245 ADP-ribosylarginine hydrolase [EC:3.2.2.19] (A)"	--	--	--	ADP-ribosylglycohydrolase	[Protein ADP-ribosylarginine] hydrolase GN=ADPRH OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ADP-ribosylarginine hydrolase [Loxodonta africana]
ENSG00000144847(IGSF11)	--	0.4779383	14	0.323952374	17	0.212438055	10	1.50235834	82	1.568467117	74	1.026966962	52	7.08E-08	2.397723256	up	1.83E-05	2.007891498	up	0.000173971	2.209065976	up	7.22E-07	2.319664651	up	--	--	--	"K06791|0|hsa:152404|IGSF11, BT-IgSF, CT119, CXADRL1, Igsf13, VSIG3; immunoglobulin superfamily, member 11; K06791 immunoglobulin superfamily, member 11 (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Immunoglobulin superfamily member 11 (Precursor) GN=IGSF11 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 11 [Leptonychotes weddellii]
ENSG00000144848(ATG3)	--	23.08706	764	22.15434	757	24.83852	833	30.44048	980	26.771126	842	24.85723	802	0.865981644	0.327793568	normal	0.968433439	0.131850541	normal	0.975669969	-0.062889333	normal	0.555175939	0.134986219	normal	--	--	--	K08343|0|ptr:470880|ATG3; autophagy related 3; K08343 ubiquitin-like-conjugating enzyme ATG3 [EC:6.3.2.19] (A)	Regulation of autophagy (ko04140)	[R]	General function prediction only	"Autophagocytosis associated protein (Atg3), N-terminal domain;; Autophagocytosis associated protein, active-site domain;; Autophagocytosis associated protein C-terminal"	Ubiquitin-like-conjugating enzyme ATG3 GN=ATG3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ubiquitin-like-conjugating enzyme ATG3 [Oryctolagus cuniculus]
ENSG00000144852(NR1I2)	--	0.011476673	1	0.011423093	1	0.039363281	1	0	0	0	0	0.04204222	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K08540|0|ggo:101124311|NR1I2; nuclear receptor subfamily 1 group I member 2 isoform 1; K08540 pregnane X receptor (A)	--	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor subfamily 1 group I member 2 GN=NR1I2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor subfamily 1 group I member 2 [Equus caballus]
ENSG00000144857(BOC)	--	2.232986129	172	3.110851809	172	2.414061325	176	4.341153792	143	4.133209	165	2.624188369	104	0.925357007	-0.294337211	normal	0.963841487	-0.080645077	normal	0.124319805	-0.758704572	normal	0.317266033	-0.357728047	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Brother of CDO (Precursor) GN=BOC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: brother of CDO isoform X2 [Equus caballus] 
ENSG00000144867(SRPRB)	--	20.5684	742	26.0961	957	21.93429	810	32.0067	1149	27.33843	1069	33.2968	1219	0.067279207	0.599051475	normal	0.971034243	0.138038002	normal	0.094214128	0.580523395	normal	0.006574689	0.432851066	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K12272|0|hsa:58477|SRPRB, APMCF1; signal recognition particle receptor, B subunit; K12272 signal recognition particle receptor subunit beta (A)"	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Signal recognition particle receptor beta subunit;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B;; Gtr1/RagA G protein conserved region	Signal recognition particle receptor subunit beta GN=SRPRB OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle receptor subunit beta [Trichechus manatus latirostris]
ENSG00000144868(TMEM108)	--	0.02195354	1	0	0	0	0	0.439616769	5	0.085433138	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 108 (Precursor) GN=TMEM108 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 108 [Odobenus rosmarus divergens]
ENSG00000144891(AGTR1)	--	0.340167165	11	0.31217385	9	0.198983642	6	1.26131522	41	1.678697268	58	1.081240009	38	0.041249046	1.734183377	normal	5.86E-06	2.481498285	up	0.001486047	2.387679049	up	1.36E-05	2.375631361	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04166|0|mcc:712773|AGTR1; angiotensin II receptor, type 1; K04166 angiotensin II receptor type 1 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Neuroactive ligand-receptor interaction (ko04080);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Renin-angiotensin system (ko04614);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Type-1 angiotensin II receptor GN=AGTR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: type-1 angiotensin II receptor isoform X1 [Oryctolagus cuniculus] 
ENSG00000144893(MED12L)	--	0.884916259	100	1.438262606	164	0.996440863	105	0.595010143	75	0.675897561	75	0.408785796	47	0.899161716	-0.438068232	normal	0.00084239	-1.134291874	down	0.011858922	-1.142701091	normal	0.043495747	-0.928308971	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Molecular Function: beta-catenin binding (GO:0008013);; Cellular Component: mediator complex (GO:0016592);; 	"K15162|0|hsa:116931|MED12L, NOPAR, TNRC11L, TRALP, TRALPUSH; mediator complex subunit 12-like; K15162 mediator of RNA polymerase II transcription subunit 12 (A)"	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	Eukaryotic Mediator 12 subunit domain;; Transcription mediator complex subunit Med12;; Eukaryotic Mediator 12 catenin-binding domain	Mediator of RNA polymerase II transcription subunit 12-like protein GN=PRO0314 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 12-like protein [Camelus dromedarius]
ENSG00000144895(EIF2A)	--	40.739713	1677	41.84865931	1716	41.236471	1628	35.39033388	1475	38.61776824	1589	37.76872308	1556	0.962671957	-0.215789002	normal	0.97876849	-0.132235841	normal	0.983021585	-0.073480255	normal	0.490810223	-0.141160122	normal	[R]	General function prediction only	--	"K15026|0|hsa:83939|EIF2A, EIF-2A, MST089, MSTP004, MSTP089; eukaryotic translation initiation factor 2A, 65kDa; K15026 translation initiation factor 2A (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Eukaryotic translation initiation factor eIF2A	"Eukaryotic translation initiation factor 2A, N-terminally processed GN=EIF2A OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 2A isoform X3 [Mustela putorius furo] 
ENSG00000144908(ALDH1L1)	--	0.350598596	19	0.221345086	15	0.186874759	10	0.017562748	1	0.014941674	0	0.107465912	3	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Biological Process: biosynthetic process (GO:0009058);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: hydroxymethyl-, formyl- and related transferase activity (GO:0016742);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00289|0|hsa:10840|ALDH1L1, 10-FTHFDH, 10-fTHF, FDH, FTHFD; aldehyde dehydrogenase 1 family, member L1 (EC:1.5.1.6); K00289 formyltetrahydrofolate dehydrogenase [EC:1.5.1.6] (A)"	One carbon pool by folate (ko00670)	[F]	Nucleotide transport and metabolism	"Aldehyde dehydrogenase family;; Formyl transferase;; Formyl transferase, C-terminal domain;; Phosphopantetheine attachment site;; Protein of unknown function (DUF1487)"	Cytosolic 10-formyltetrahydrofolate dehydrogenase GN=ALDH1L1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	Aldehyde dehydrogenase family 1 member L1 [Myotis brandtii]
ENSG00000144909(OSBPL11)	--	5.834737717	499	5.990908898	514	5.500271889	470	5.857034767	513	6.375455504	544	6.323782199	537	0.971815982	0.009059237	normal	0.970021674	0.060239446	normal	0.952870462	0.183417393	normal	0.786144857	0.082965766	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Oxysterol-binding protein;; PH domain;; Pleckstrin homology domain	Oxysterol-binding protein-related protein 11 GN=OSBPL11 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: oxysterol-binding protein-related protein 11 [Vicugna pacos]
ENSG00000144935(TRPC1)	--	9.88867886	579	9.7974408	576	10.57722104	597	9.571103632	574	8.821906282	506	8.495633304	489	0.972404747	-0.043229661	normal	0.945740459	-0.207775471	normal	0.89613136	-0.295359774	normal	0.455252974	-0.180802113	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04964|0|hsa:7220|TRPC1, HTRP-1, TRP1; transient receptor potential cation channel, subfamily C, member 1; K04964 transient receptor potential cation channel subfamily C member 1 (A)"	Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Pancreatic secretion (ko04972)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Transient receptor ion channel II;; Ion transport protein;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies)	Short transient receptor potential channel 1 GN=TRPC1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: short transient receptor potential channel 1 isoform X1 [Vicugna pacos]
ENSG00000144959(NCEH1)	--	29.13597002	2035	32.12462	1996	32.0087972	2201	37.68701474	2601	25.66605182	1785	29.3688375	1862	0.911510126	0.322989197	normal	0.973810009	-0.182467919	normal	0.956724036	-0.249410967	normal	0.971851655	-0.018512988	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14349|0|hsa:57552|NCEH1, AADACL1, NCEH; neutral cholesterol ester hydrolase 1 (EC:3.1.1.-); K14349 neutral cholesterol ester hydrolase 1 [EC:3.1.1.-] (A)"	Bile secretion (ko04976)	[V]	Defense mechanisms	alpha/beta hydrolase fold	Neutral cholesterol ester hydrolase 1 GN=NCEH1 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: LOW QUALITY PROTEIN: neutral cholesterol ester hydrolase 1 [Galeopterus variegatus]
ENSG00000145002(FAM86B2)	--	0.574181	8	0.334914	4	0.445904	4	0.350438	4	0.2555902	2	0.164795	2	--	--	--	--	--	--	--	--	--	--	--	--	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[R]	General function prediction only	Family of unknown function;; Putative methyltransferase	Putative protein N-methyltransferase FAM86B2 {ECO:0000305} GN=FAM86B2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM86A isoform X1 [Galeopterus variegatus]
ENSG00000145012(LPP)	--	24.36594564	3115	38.66991325	3783	28.69507217	3188	41.44279031	5679	57.39242159	5051	50.03223251	5342	8.51E-05	0.835263093	normal	0.850918064	0.395474463	normal	0.001952249	0.736164197	normal	5.35E-06	0.650595234	normal	--	--	--	K16676|0|hsa:4026|LPP; LIM domain containing preferred translocation partner in lipoma; K16676 lipoma-prefererred partner (A)	--	[T]	Signal transduction mechanisms	LIM domain	Lipoma-preferred partner GN=LPP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: lipoma-preferred partner isoform X1 [Panthera tigris altaica] 
ENSG00000145014(TMEM44)	--	9.056804037	362	7.311040564	275	8.949439	332	8.019247121	306	7.873689411	300	6.33963441	243	0.91519965	-0.272032682	normal	0.961798375	0.103558972	normal	0.654530755	-0.456079949	normal	0.476322227	-0.212420844	normal	--	--	--	--	--	--	--	--	Transmembrane protein 44 GN=TMEM44 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane protein 44 [Ceratotherium simum simum]
ENSG00000145016(RUBCN)	--	3.660848892	315	3.601803015	449	3.367598561	379	3.754935148	388	3.46712813	343	3.943492831	410	0.916692838	0.268690036	normal	0.733838646	-0.408354583	normal	0.964488362	0.104732737	normal	0.958499295	-0.023695629	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4206);; RUN domain	Run domain Beclin-1 interacting and cysteine-rich containing protein GN=KIAA0226 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	hypothetical protein PANDA_004914 [Ailuropoda melanoleuca]
ENSG00000145020(AMT)	--	11.4697584	405	9.029206003	330	9.309053943	311	10.59354347	345	10.55319991	354	9.885868608	350	0.920517283	-0.261083235	normal	0.964800153	0.079504964	normal	0.955079214	0.161408661	normal	0.973081533	-0.01724463	normal	[E]	Amino acid transport and metabolism	--	"K00605|0|hsa:275|AMT, GCE, GCST, GCVT, NKH; aminomethyltransferase (EC:2.1.2.10); K00605 aminomethyltransferase [EC:2.1.2.10] (A)"	"Glycine, serine and threonine metabolism (ko00260);; One carbon pool by folate (ko00670);; Carbon metabolism (ko01200)"	[E]	Amino acid transport and metabolism	Aminomethyltransferase folate-binding domain;; Glycine cleavage T-protein C-terminal barrel domain	"Aminomethyltransferase, mitochondrial (Precursor) GN=AMT OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: aminomethyltransferase, mitochondrial isoform 1 [Equus caballus] "
ENSG00000145022(TCTA)	--	11.69927015	440	12.69792	475	13.12591502	497	8.637332613	324	7.74874	277	11.02523684	415	0.551283904	-0.470419278	normal	0.004099613	-0.79610682	normal	0.916662257	-0.267533821	normal	0.015588288	-0.495204743	normal	--	--	--	--	--	--	--	T-cell leukemia translocation-altered	T-cell leukemia translocation-altered gene protein GN=TCTA OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: T-cell leukemia translocation-altered gene protein [Oryctolagus cuniculus]
ENSG00000145040(UCN2)	--	2.24595	60	2.13217	58	1.443	39	4.55217	123	5.22571	139	5.99853	162	0.035050701	0.986797453	normal	0.000808868	1.218397781	up	1.39E-10	2.004869236	up	2.18E-05	1.412269977	up	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	"K05257|2.27652e-24|hsa:90226|UCN2, SRP, UCN-II, UCNI, UR, URP; urocortin 2; K05257 urocortin 2/3 (A)"	--	--	--	"Agonist of corticotropin releasing factor R2, Urocortin-2"	Urocortin-2 (Precursor) GN=UCN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	urocortin-2 precursor [Bos taurus] 
ENSG00000145041(DCAF1)	--	8.62955229	1020	9.944088716	1146	8.454204109	995	7.443528549	884	9.046281574	1064	8.470984032	1000	0.943672652	-0.236899409	normal	0.97357435	-0.128359605	normal	0.979588389	-0.001058268	normal	0.587296998	-0.121581211	normal	--	--	--	K11789|0|ptr:470820|VPRBP; Vpr (HIV-1) binding protein; K11789 HIV-1 Vpr-binding protein (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	Protein VPRBP GN=VPRBP OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: protein VPRBP isoform X2 [Ursus maritimus]
ENSG00000145050(MANF)	--	38.6978	885	34.9102	831	34.0845	808	46.3621	1070	37.3656	844	41.9579	961	0.941501933	0.242645622	normal	0.976973127	0.000966219	normal	0.9401892	0.241474795	normal	0.430169146	0.16613593	normal	--	--	--	--	--	[R]	General function prediction only	Degradation arginine-rich protein for mis-folding	Mesencephalic astrocyte-derived neurotrophic factor (Precursor) GN=MANF OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: mesencephalic astrocyte-derived neurotrophic factor [Ochotona princeps]
ENSG00000145075(CCDC39)	--	0.4501569	7	0.721616	14	1.045498	13	0.4498474	9	0.3819956	2	0.8235734	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 39 GN=CCDC39 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 39 [Ceratotherium simum simum]
ENSG00000145087(STXBP5L)	--	0.01284406	2	0.038739306	6	0.058166934	8	0.025500051	4	0.037211336	5	0.012718277	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K08518|0|ptr:460617|STXBP5L; syntaxin binding protein 5-like; K08518 syntaxin-binding protein 5 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"LLGL2;; WD domain, G-beta repeat;; Lethal giant larvae(Lgl) like, C-terminal"	Syntaxin-binding protein 5-like GN=STXBP5L OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-binding protein 5-like [Ceratotherium simum simum]
ENSG00000145088(EAF2)	--	3.254673715	53	2.782811245	45	1.53107497	23	1.688773309	28	1.718571146	28	1.023998186	17	0.656566135	-0.914319885	normal	0.906520264	-0.676825428	normal	0.983349941	-0.412718949	normal	0.254723633	-0.752604152	normal	--	--	--	"K15186|1.08591e-141|hsa:55840|EAF2, BM040, TRAITS, U19; ELL associated factor 2; K15186 ELL-associated factor (A)"	--	[K]	Transcription	RNA polymerase II transcription elongation factor	ELL-associated factor 2 GN=EAF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ELL-associated factor 2 [Ursus maritimus]
ENSG00000145103(ILDR1)	--	0	0	0	0	0	0	0	0	0	0	0.019253645	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lipolysis stimulated receptor (LSR)	Immunoglobulin-like domain-containing receptor 1 (Precursor) GN=ILDR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: immunoglobulin-like domain-containing receptor 1 isoform X1 [Tupaia chinensis]
ENSG00000145107(TM4SF19)	--	4.345738663	237	4.98953306	278	7.267034337	271	5.698157143	246	4.1118518	184	6.741236133	340	0.966873462	0.022793954	normal	0.249083711	-0.612678215	normal	0.884557939	0.317366126	normal	0.939818422	-0.049888675	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	L6 membrane protein;; Putative binding domain	Transmembrane 4 L6 family member 19 GN=TM4SF19 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane 4 L6 family member 19 [Ursus maritimus] 
ENSG00000145113(MUC4)	--	0.026968	2	0.09283235	7	0.03901039	2	0	0	0.05239743	4	0.0398812	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell-matrix adhesion (GO:0007160);; 	--	--	--	--	Nidogen-like;; AMOP domain;; von Willebrand factor type D domain	Mucin-4 beta chain (Precursor) GN=MUC4 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: mucin-4 [Galeopterus variegatus]
ENSG00000145147(SLIT2)	--	0	0	0	0	0	0	0.040775402	4	0.125409273	4	0.050694582	5	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K06839|0|mcf:101866138|uncharacterized LOC101866138; K06839 slit 2 (A)	Axon guidance (ko04360)	[WT]	Extracellular structures;; Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; EGF-like domain;; Leucine rich repeats (6 copies);; Laminin G domain;; Leucine Rich Repeat;; Laminin G domain;; Leucine rich repeat N-terminal domain;; Leucine-rich repeat;; Leucine rich repeat C-terminal domain;; Human growth factor-like EGF	Slit homolog 2 protein C-product (Precursor) GN=SLIT2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: slit homolog 2 protein isoform 5 [Ovis aries]
ENSG00000145191(EIF2B5)	--	11.859851	582	12.17027	573	12.96923	619	14.64679	688	15.05143	724	13.12348	643	0.947305274	0.210046707	normal	0.878761557	0.315286271	normal	0.973387892	0.046476473	normal	0.395708748	0.190918379	normal	[MJ]	"Cell wall/membrane/envelope biogenesis;; Translation, ribosomal structure and biogenesis"	Molecular Function: protein binding (GO:0005515);; 	"K03240|0|hsa:8893|EIF2B5, CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM; eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; K03240 translation initiation factor eIF-2B subunit epsilon (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	eIF4-gamma/eIF5/eIF2-epsilon;; Bacterial transferase hexapeptide (six repeats)	Translation initiation factor eIF-2B subunit epsilon GN=EIF2B5 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: translation initiation factor eIF-2B subunit epsilon [Eptesicus fuscus]
ENSG00000145192(AHSG)	--	0.065186238	2	0.138860407	4	0	0	0.105227525	3	0.102366704	2	0.069312283	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	--	--	--	--	Cystatin domain	Alpha-2-HS-glycoprotein chain B (Precursor) GN=AHSG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: alpha-2-HS-glycoprotein [Pteropus alecto] 
ENSG00000145194(ECE2)	--	5.340780003	161	6.268580011	190	5.561790013	170	4.361020015	131	5.692920003	170	6.123500008	186	0.915330165	-0.324881878	normal	0.952418644	-0.180372519	normal	0.961828435	0.120451746	normal	0.799031518	-0.11756779	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	K01415|0|ggo:101149703|ECE2; endothelin-converting enzyme 2 isoform 1; K01415 endothelin-converting enzyme [EC:3.4.24.71] (A)	--	[E]	Amino acid transport and metabolism	Peptidase family M13;; Peptidase family M13;; Methyltransferase domain;; Methyltransferase domain	Endothelin-converting enzyme 2 region GN=ECE2 OS=Homo sapiens (Human) PE=1 SV=4	E	Amino acid transport and metabolism	PREDICTED: endothelin-converting enzyme 2 isoform 2 [Orcinus orca]
ENSG00000145198(VWA5B2)	--	0.96915327	72	0.5554447	41	0.563477138	40	0.404348311	32	0.60241788	46	0.244514746	17	0.074125905	-1.162532892	normal	0.977706042	0.139716309	normal	0.545016936	-1.172856989	normal	0.338237381	-0.710278016	normal	--	--	--	--	--	--	--	von Willebrand factor type A domain;; Vault protein inter-alpha-trypsin domain	von Willebrand factor A domain-containing protein 5B2 GN=VWA5B2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: von Willebrand factor A domain-containing protein 5B2 [Galeopterus variegatus]
ENSG00000145214(DGKQ)	--	3.880305448	348	3.827680777	310	3.300803026	309	3.832761074	342	4.143186831	323	3.27364015	296	0.967228205	-0.05567528	normal	0.966549067	0.037659411	normal	0.965787228	-0.069951283	normal	0.949356766	-0.030682947	normal	--	--	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Biological Process: signal transduction (GO:0007165);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|hsa:1609|DGKQ, DAGK, DAGK4, DAGK7; diacylglycerol kinase, theta 110kDa (EC:2.7.1.107); K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Ras association (RalGDS/AF-6) domain	Diacylglycerol kinase theta GN=DGKQ OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: diacylglycerol kinase theta [Odobenus rosmarus divergens]
ENSG00000145217(SLC26A1)	--	1.041075003	49	1.080156	54	0.839913	50	0.913425	50	0.990994	48	1.658912	87	0.979286637	-0.001635163	normal	0.97340045	-0.185828028	normal	0.531498164	0.77286223	normal	0.704308168	0.254402739	normal	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14700|0|hsa:10861|SLC26A1, EDM4, SAT-1, SAT1; solute carrier family 26 (anion exchanger), member 1; K14700 solute carrier family 26 (sulfate anion transporter), member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain	Sulfate anion transporter 1 GN=SLC26A1 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sulfate anion transporter 1 [Vicugna pacos]
ENSG00000145220(LYAR)	--	9.371449033	339	10.09563	365	9.49633106	343	10.70700276	391	11.26583776	405	7.012614022	254	0.952569215	0.174315011	normal	0.960491204	0.128094894	normal	0.690961694	-0.439411473	normal	0.977448148	-0.018197578	normal	--	--	--	"K15263|0|hsa:55646|LYAR, ZC2HC2, ZLYAR; Ly1 antibody reactive; K15263 cell growth-regulating nucleolar protein (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	LYAR-type C2HC zinc finger	Cell growth-regulating nucleolar protein GN=LYAR OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cell growth-regulating nucleolar protein [Equus caballus]
ENSG00000145241(CENPC)	--	1.678018436	195	2.139479674	246	1.996496337	226	1.725402427	202	1.826456883	213	1.731920391	202	0.966872255	0.019894894	normal	0.938398608	-0.227725432	normal	0.954326731	-0.16906164	normal	0.735613505	-0.133578096	normal	--	--	--	"K11497|0|hsa:1060|CENPC, CENP-C, CENPC1, MIF2, hcp-4; centromere protein C; K11497 centromere protein C (A)"	--	--	--	Kinetochore assembly subunit CENP-C N-terminal;; Centromere assembly component CENP-C middle DNMT3B-binding region;; Mif2/CENP-C like;; Cupin domain	Centromere protein C GN=CENPC OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centromere protein C isoform X1 [Galeopterus variegatus]
ENSG00000145242(EPHA5)	--	4.711021422	278	4.223912298	260	4.839636124	268	2.29853182	173	3.586895451	242	2.694739612	204	0.067820491	-0.710119793	normal	0.959243274	-0.124182236	normal	0.805725829	-0.399364066	normal	0.142418311	-0.4014296	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05106|0|hsa:2044|EPHA5, CEK7, EHK-1, EHK1, EK7, HEK7, TYRO4; EPH receptor A5 (EC:2.7.10.1); K05106 Eph receptor A5 [EC:2.7.10.1] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; SAM domain (Sterile alpha motif);; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif)	Ephrin type-A receptor 5 (Precursor) GN=EPHA5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 5 isoform X1 [Tupaia chinensis]
ENSG00000145244(CORIN)	--	0	0	0	0	0.023368321	1	0	0	0.022963891	1	0.023455898	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K09614|0|ptr:740125|CORIN; corin, serine peptidase; K09614 corin [EC:3.4.21.-] (A)"	--	[T]	Signal transduction mechanisms	Trypsin;; Low-density lipoprotein receptor domain class A;; Fz domain;; Scavenger receptor cysteine-rich domain	"Atrial natriuretic peptide-converting enzyme, 100 kDa soluble fragment GN=CORIN OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: atrial natriuretic peptide-converting enzyme [Panthera tigris altaica]
ENSG00000145246(ATP10D)	--	2.21527829	244	2.335934214	232	2.19850518	211	2.627184261	289	2.73963016	299	2.604318711	297	0.942920652	0.212127662	normal	0.866571708	0.342622247	normal	0.611902076	0.482003117	normal	0.2057802	0.344075779	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:57205|ATP10D, ATPVD; ATPase, class V, type 10D (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase VD GN=ATP10D OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase VD isoform X1 [Equus przewalskii]
ENSG00000145247(OCIAD2)	--	42.52549	681	42.34634	641	45.64102	687	93.86373	1476	85.42268	1308	75.53150437	1182	3.54E-08	1.083434159	up	1.18E-06	1.005844674	up	0.001064707	0.773243338	normal	1.52E-11	0.959416977	normal	--	--	--	--	--	--	--	Ovarian carcinoma immunoreactive antigen (OCIA)	OCIA domain-containing protein 2 GN=OCIAD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: OCIA domain-containing protein 2 isoform X1 [Orycteropus afer afer]
ENSG00000145248(SLC10A4)	--	4.72992	120	3.1829	82	4.74471	124	5.52313	143	5.15552	131	3.94906	102	0.952063248	0.219570751	normal	0.539930123	0.64495545	normal	0.941385981	-0.286207496	normal	0.713453307	0.184162261	normal	[R]	General function prediction only	Cellular Component: membrane (GO:0016020);; 	"K14344|0|hsa:201780|SLC10A4, P4; solute carrier family 10, member 4; K14344 solute carrier family 10 (sodium/bile acid cotransporter), member 4 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium Bile acid symporter family	Sodium/bile acid cotransporter 4 GN=SLC10A4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/bile acid cotransporter 4 [Chrysochloris asiatica]
ENSG00000145283(SLC10A6)	--	0	0	0	0	0	0	0	0	0	0	0.0433144	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Cellular Component: membrane (GO:0016020);; 	"K14346|0|hsa:345274|SLC10A6, SOAT; solute carrier family 10 (sodium/bile acid cotransporter), member 6; K14346 solute carrier family 10 (sodium/bile acid cotransporter), member 6 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium Bile acid symporter family	Solute carrier family 10 member 6 GN=SLC10A6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 10 member 6 isoform X1 [Felis catus]
ENSG00000145284(SCD5)	--	15.521181	701	13.569471	551	19.2472944	647	15.395586	587	14.303113	552	14.331034	514	0.905033664	-0.286199603	normal	0.971950117	-0.01875917	normal	0.845412188	-0.339396707	normal	0.316495253	-0.221632156	normal	[I]	Lipid transport and metabolism	Biological Process: lipid metabolic process (GO:0006629);; 	K00507|0|pps:100971802|SCD5; stearoyl-CoA desaturase 5; K00507 stearoyl-CoA desaturase (delta-9 desaturase) [EC:1.14.19.1] (A)	Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; AMPK signaling pathway (ko04152)	[I]	Lipid transport and metabolism	Fatty acid desaturase	Stearoyl-CoA desaturase 5 GN=SCD5 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: stearoyl-CoA desaturase 5 [Ceratotherium simum simum]
ENSG00000145287(PLAC8)	--	0.2564563	4	0.481595438	3	0.281357479	3	0.923435653	7	1.161172893	5	1.127836052	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PLAC8 family	Placenta-specific gene 8 protein GN=PLAC8 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: placenta-specific gene 8 protein [Leptonychotes weddellii]
ENSG00000145293(ENOPH1)	--	19.05345844	644	18.95089073	646	21.2379037	720	24.039834	824	20.6773945	683	21.212246	731	0.867452272	0.324066462	normal	0.972736174	0.058791	normal	0.975825033	0.013554802	normal	0.579236144	0.133585651	normal	[C]	Energy production and conversion	--	K09880|0|pps:100974648|ENOPH1; enolase-phosphatase 1; K09880 enolase-phosphatase E1 [EC:3.1.3.77] (A)	Cysteine and methionine metabolism (ko00270)	[E]	Amino acid transport and metabolism	Haloacid dehalogenase-like hydrolase	Enolase-phosphatase E1 {ECO:0000255|HAMAP-Rule:MF_03117} OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: enolase-phosphatase E1 isoform X1 [Oryctolagus cuniculus]
ENSG00000145331(TRMT10A)	--	2.290516716	94	2.766651313	97	1.411130647	70	2.352548274	112	2.138087458	100	1.916955826	82	0.957765492	0.218656575	normal	0.969592996	0.022176279	normal	0.964744517	0.215668629	normal	0.800513651	0.149129676	normal	--	--	--	"K15445|0|hsa:93587|TRMT10A, HEL-S-88, MSSGM, RG9MTD2, TRM10; tRNA methyltransferase 10 homolog A (S. cerevisiae); K15445 tRNA (guanine9-N1)-methyltransferase [EC:2.1.1.221] (A)"	--	[S]	Function unknown	tRNA (Guanine-1)-methyltransferase	tRNA methyltransferase 10 homolog A GN=TRMT10A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: tRNA methyltransferase 10 homolog A isoform X2 [Canis lupus familiaris]
ENSG00000145332(KLHL8)	--	4.941765801	379	4.694751653	374	4.684604195	394	5.878955442	488	6.832332242	555	6.157738434	492	0.857873055	0.332659973	normal	0.264577975	0.546199121	normal	0.881935052	0.311100602	normal	0.05433879	0.399360466	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10446|0|hsa:57563|KLHL8; kelch-like family member 8; K10446 kelch-like protein 8 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Kelch motif"	Kelch-like protein 8 GN=KLHL8 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 8 isoform X1 [Felis catus] 
ENSG00000145335(SNCA)	--	8.824597312	202	6.239907299	157	7.371452	162	5.457483303	121	5.81220789	129	7.311235705	167	0.077545987	-0.762598686	normal	0.924594439	-0.301609248	normal	0.967033921	0.035238844	normal	0.342009894	-0.341589347	normal	--	--	--	"K04528|4.6541e-67|ptr:461375|SNCA; synuclein, alpha (non A4 component of amyloid precursor); K04528 synuclein, alpha (non A4 component of amyloid precursor) (A)"	Alzheimer's disease (ko05010);; Parkinson's disease (ko05012)	--	--	Synuclein	Alpha-synuclein GN=SNCA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	alpha-synuclein [Sus scrofa] 
ENSG00000145337(PYURF)	--	42.0704	766	44.8606	836	44.7365	827	52.7773	978	47.7995	870	41.53	761	0.87474812	0.321086677	normal	0.976681155	0.036022025	normal	0.969436693	-0.12803816	normal	0.752767356	0.081226875	normal	[S]	Function unknown	--	--	--	--	--	Trm112p-like protein	"Protein preY, mitochondrial (Precursor) GN=PYURF OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit Y-like isoform 1 [Ovis aries]
ENSG00000145348(TBCK)	--	3.274856792	199	3.615003588	192	4.702784901	231	4.36349728	270	4.215299519	254	4.882912393	290	0.795289846	0.406654407	normal	0.83860667	0.379688063	normal	0.890108132	0.318006763	normal	0.189565437	0.367420707	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17544|0|hsa:93627|TBCK, TBCKL; TBC1 domain containing kinase; K17544 TBC domain-containing protein kinase-like protein (A)"	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; Protein kinase domain;; Protein tyrosine kinase;; Rhodanese-like domain;; Kinase-like	TBC domain-containing protein kinase-like protein GN=HSPC302 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: TBC domain-containing protein kinase-like protein isoform X1 [Mustela putorius furo] 
ENSG00000145349(CAMK2D)	--	24.07768344	1210	21.47646238	1179	27.11591963	1232	17.23688042	1040	26.44047182	1108	18.44201423	906	0.941702291	-0.248914447	normal	0.975919603	-0.110885645	normal	0.539216389	-0.451062455	normal	0.130877663	-0.267147929	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: calmodulin-dependent protein kinase activity (GO:0004683);; Molecular Function: calmodulin binding (GO:0005516);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04515|0|mcc:702504|CAMK2D; calcium/calmodulin-dependent protein kinase II delta; K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] (A)	ErbB signaling pathway (ko04012);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; HIF-1 signaling pathway (ko04066);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Wnt signaling pathway (ko04310);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; Proteoglycans in cancer (ko05205);; Glioma (ko05214)	[T]	Signal transduction mechanisms	Protein kinase domain;; Calcium/calmodulin dependent protein kinase II Association;; Protein tyrosine kinase;; Domain of unknown function (DUF4440);; SnoaL-like domain	Calcium/calmodulin-dependent protein kinase type II subunit delta GN=CAMK2D OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type II subunit delta isoform X2 [Ochotona princeps]
ENSG00000145354(CISD2)	--	28.3997	779	33.30124193	914	28.73338017	814	35.91124	997	29.28550201	807	33.21640028	987	0.870738005	0.324570877	normal	0.955219718	-0.200698372	normal	0.92456153	0.269274872	normal	0.555432618	0.133400238	normal	--	--	"Cellular Component: intracellular membrane-bounded organelle (GO:0043231);; Molecular Function: 2 iron, 2 sulfur cluster binding (GO:0051537);; "	--	--	[R]	General function prediction only	Iron-binding zinc finger CDGSH type;; Iron-containing outer mitochondrial membrane protein N-terminus	CDGSH iron-sulfur domain-containing protein 2 GN=CISD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CDGSH iron-sulfur domain-containing protein 2 [Capra hircus]
ENSG00000145358(DDIT4L)	--	2.155564766	76	2.210940529	82	1.58207347	57	2.873824	107	3.456167884	126	3.745100802	138	0.883725643	0.454924338	normal	0.676488276	0.589470378	normal	0.000506995	1.2454413	up	0.036723356	0.766110944	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: negative regulation of signal transduction (GO:0009968);; 	--	--	--	--	RTP801 C-terminal region	DNA damage-inducible transcript 4-like protein GN=DDIT4L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: DNA damage-inducible transcript 4-like protein [Ochotona princeps]
ENSG00000145362(ANK2)	--	2.74450157	411	2.657456105	459	4.110334429	477	3.383972868	502	2.072131112	379	3.29949616	580	0.922751214	0.256846792	normal	0.895656324	-0.296645407	normal	0.913636371	0.272986146	normal	0.805133092	0.096490521	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K10380|0|ggo:101133513|ANK2; ankyrin-2 isoform 1; K10380 ankyrin (A)	Proteoglycans in cancer (ko05205)	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; ZU5 domain;; Death domain	Ankyrin-2 GN=ANK2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: ankyrin-2 [Ursus maritimus]
ENSG00000145365(TIFA)	--	3.260345175	140	3.220421507	141	2.345254031	116	3.829875028	161	4.480093204	196	3.419163245	150	0.957801691	0.169070422	normal	0.780978817	0.44962524	normal	0.903724276	0.358426468	normal	0.370531019	0.331249686	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	FHA domain	TRAF-interacting protein with FHA domain-containing protein A GN=TIFA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: TRAF-interacting protein with FHA domain-containing protein A [Ceratotherium simum simum]
ENSG00000145375(SPATA5)	--	2.729466057	264	2.654053253	281	2.589226182	278	3.054219876	307	2.033513379	197	2.024851202	201	0.94957995	0.185864706	normal	0.488137396	-0.5303729	normal	0.650914701	-0.473140311	normal	0.453393299	-0.245930604	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	"K14575|0|hsa:166378|SPATA5, AFG2, SPAF; spermatogenesis associated 5; K14575 AAA family ATPase (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATPase family associated with various cellular activities (AAA);; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (dynein-related subfamily);; AAA ATPase domain;; TIP49 C-terminus;; AAA domain;; AAA domain;; AAA domain (Cdc48 subfamily);; Zeta toxin;; AAA domain;; Magnesium chelatase, subunit ChlI;; AAA domain;; AAA domain;; AAA domain;; IstB-like ATP binding protein;; RNA helicase;; ATPase family associated with various cellular activities (AAA);; Parvovirus non-structural protein NS1"	Spermatogenesis-associated protein 5 GN=SPATA5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: spermatogenesis-associated protein 5 isoform 1 [Ceratotherium simum simum]
ENSG00000145384(FABP2)	--	0.030076	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08751|3.74018e-90|hsa:2169|FABP2, FABPI, I-FABP; fatty acid binding protein 2, intestinal; K08751 fatty acid-binding protein 2, intestinal (A)"	PPAR signaling pathway (ko03320);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin / cytosolic fatty-acid binding protein family	"Fatty acid-binding protein, intestinal GN=FABP2 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: fatty acid-binding protein, intestinal [Dasypus novemcinctus]"
ENSG00000145386(CCNA2)	--	24.3695	1121	25.22708	1157	26.4349	1202	32.537528	1499	27.0106	1240	27.5748	1270	0.76421376	0.387920685	normal	0.97898691	0.078425671	normal	0.980240617	0.07101323	normal	0.345736184	0.182483685	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	"K06627|0|hsa:890|CCNA2, CCN1, CCNA; cyclin A2; K06627 cyclin A (A)"	Cell cycle (ko04110);; AMPK signaling pathway (ko04152);; Progesterone-mediated oocyte maturation (ko04914);; Hepatitis B (ko05161);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	Cyclin-A2 GN=CCNA2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-A2 [Ceratotherium simum simum]
ENSG00000145388(METTL14)	--	4.6472811	443	5.116263139	488	5.234940631	474	5.315740831	473	3.670260762	413	4.571640109	440	0.969047159	0.063488115	normal	0.920090319	-0.26128458	normal	0.964534493	-0.115293089	normal	0.726808553	-0.104938746	normal	--	--	Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: methyltransferase activity (GO:0008168);; 	K05925|0|ptr:461454|METTL14; methyltransferase like 14; K05925 mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] (A)	--	[K]	Transcription	MT-A70	N6-adenosine-methyltransferase subunit METTL14 GN=METTL14 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: methyltransferase-like protein 14 [Balaenoptera acutorostrata scammoni]
ENSG00000145390(USP53)	--	5.221827546	535	8.558171594	855	6.52086016	644	7.91524286	799	7.398987604	754	10.65498261	1074	0.198563035	0.546532351	normal	0.953501452	-0.202404922	normal	0.003807706	0.728231643	normal	0.393998785	0.34853389	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase	Inactive ubiquitin carboxyl-terminal hydrolase 53 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: inactive ubiquitin carboxyl-terminal hydrolase 53 [Galeopterus variegatus]
ENSG00000145391(SETD7)	--	25.05599205	2752	31.19404104	3230	29.3605172	3219	38.3849204	4161	33.974394	3730	32.91139058	3661	0.140996464	0.565359222	normal	0.982188279	0.186133757	normal	0.983307264	0.17725562	normal	0.060376359	0.306775629	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K11431|0|nle:100602353|uncharacterized LOC100602353; K11431 histone-lysine N-methyltransferase SETD7 [EC:2.1.1.43] (A)	Lysine degradation (ko00310);; FoxO signaling pathway (ko04068)	[K]	Transcription	MORN repeat;; SET domain	Histone-lysine N-methyltransferase SETD7 GN=SETD7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone-lysine N-methyltransferase SETD7 isoform X1 [Felis catus]
ENSG00000145414(NAF1)	--	9.857638	569	9.310487782	522	9.913187844	611	9.729393	531	9.957334	570	7.53858959	464	0.964321284	-0.13018505	normal	0.966769343	0.105193854	normal	0.71643047	-0.404187274	normal	0.581785096	-0.142352231	normal	--	--	Biological Process: pseudouridine synthesis (GO:0001522);; Biological Process: ribosome biogenesis (GO:0042254);; 	K14763|0|pps:100970826|NAF1; nuclear assembly factor 1 ribonucleoprotein; K14763 H/ACA ribonucleoprotein complex non-core subunit NAF1 (A)	--	[S]	Function unknown	Gar1/Naf1 RNA binding region	H/ACA ribonucleoprotein complex non-core subunit NAF1 GN=NAF1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: H/ACA ribonucleoprotein complex non-core subunit NAF1 [Equus przewalskii]
ENSG00000145416(MARCH1)	--	0.916150949	78	1.205197728	102	0.829374134	69	1.053850521	91	0.747982673	64	0.938898419	81	0.965413522	0.188127008	normal	0.598383272	-0.680987337	normal	0.964759912	0.218607745	normal	0.890265455	-0.099584541	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10656|0|pps:100969079|MARCH1; membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase; K10656 E3 ubiquitin-protein ligase MARCH1/8 [EC:6.3.2.19] (A)"	--	[A]	RNA processing and modification	RING-variant domain	E3 ubiquitin-protein ligase MARCH1 GN=MARCH1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	E3 ubiquitin-protein ligase MARCH1 [Pteropus alecto]
ENSG00000145423(SFRP2)	--	0	0	0	0	0	0	0	0	0	0	0.0298801	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K02176|0|mcf:102147309|SFRP2; secreted frizzled-related protein 2; K02176 secreted frizzled-related protein 2 (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Fz domain;; UNC-6/NTR/C345C module	Secreted frizzled-related protein 2 (Precursor) GN=SFRP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: secreted frizzled-related protein 2 [Elephantulus edwardii] 
ENSG00000145425(RPS3A)	--	852.5469228	12507	807.2865369	11801	804.7949546	11768	947.925206	14065	940.4816523	13671	851.6604364	12578	0.995577069	0.138525458	normal	0.993246582	0.190760374	normal	0.996239554	0.08773104	normal	0.552787831	0.138686654	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02984|0|myb:102249340|RPS3A; ribosomal protein S3A; K02984 small subunit ribosomal protein S3Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal S3Ae family	40S ribosomal protein S3a {ECO:0000255|HAMAP-Rule:MF_03122} OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S3a [Myotis brandtii]
ENSG00000145428(RNF175)	--	0.09923879	2	0.118406378	3	0.156166	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 175 GN=RNF175 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 175 isoform X1 [Oryctolagus cuniculus]
ENSG00000145431(PDGFC)	--	12.46307919	594	11.5208624	499	12.96257287	578	12.4617125	571	13.77161532	635	11.08225929	507	0.969830403	-0.087573386	normal	0.866098679	0.325414141	normal	0.949883548	-0.19682491	normal	0.972589608	0.014507038	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	"K05450|0|hsa:56034|PDGFC, FALLOTEIN, SCDGF; platelet derived growth factor C; K05450 platelet derived growth factor C/D (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; Prostate cancer (ko05215);; Melanoma (ko05218);; Choline metabolism in cancer (ko05231)	--	--	CUB domain;; PDGF/VEGF domain	"Platelet-derived growth factor C, receptor-binding form (Precursor) GN=PDGFC OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: platelet-derived growth factor C isoform X1 [Felis catus] 
ENSG00000145439(CBR4)	--	9.74256	399	8.929395	383	9.27233	373	8.70069	375	9.850249	408	10.008646	409	0.962449009	-0.119854227	normal	0.966601493	0.069532178	normal	0.962083251	0.124152923	normal	0.956980171	0.024513347	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K11539|3.74625e-146|hsa:84869|CBR4, SDR45C1; carbonyl reductase 4 (EC:1.1.1.-); K11539 carbonyl reductase 4 [EC:1.1.1.-] (A)"	--	[I]	Lipid transport and metabolism	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Carbonyl reductase family member 4 GN=CBR4 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: carbonyl reductase family member 4 [Tupaia chinensis]
ENSG00000145451(GLRA3)	--	0.03105644	4	0	0	0	0	0.044018673	3	0.00747396	0	0.043980924	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05195|0|pon:100443609|GLRA3; glycine receptor, alpha 3; K05195 glycine receptor alpha-3 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Glycine receptor subunit alpha-3 (Precursor) GN=GLRA3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: glycine receptor subunit alpha-3 isoform X1 [Equus przewalskii]
ENSG00000145476(CYP4V2)	--	2.034007773	157	1.85175527	130	1.761851	117	1.816346516	133	2.125818186	126	2.700606482	186	0.937980536	-0.267324243	normal	0.966256362	-0.065737632	normal	0.314210368	0.65374338	normal	0.817059731	0.118934441	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07427|0|hsa:285440|CYP4V2, BCD, CYP4AH1; cytochrome P450, family 4, subfamily V, polypeptide 2 (EC:1.14.13.199); K07427 cytochrome P450, family 4, subfamily V (A)"	--	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 4V2 GN=CYP4V2 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 4V2 [Galeopterus variegatus]
ENSG00000145491(ROPN1L)	--	0.713226	12	0.907066491	15	0.609757	10	0.708876	12	0.632827	10	0.362875708	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Ropporin-1-like protein GN=ROPN1L OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ropporin-1-like protein [Vicugna pacos]
ENSG00000145494(NDUFS6)	--	77.311877	723	83.14879	797	84.74076814	806	89.19031708	875	76.12121	720	81.88165	768	0.936613807	0.243983254	normal	0.961470559	-0.167674457	normal	0.974298134	-0.07781538	normal	1	0.001190821	normal	--	--	--	"K03939|1.26919e-69|ptr:742848|NDUFS6; NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase); K03939 NADH dehydrogenase (ubiquinone) Fe-S protein 6 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Zinc-finger domain	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial (Precursor) GN=NDUFS6 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial [Myotis davidii]"
ENSG00000145495(MARCH6)	--	49.76749174	3003	45.40409428	3089	46.580518	2961	45.89883731	3079	43.59668138	2872	44.86816053	3035	0.990331054	0.00522249	normal	0.986187192	-0.12644646	normal	0.990072171	0.027306808	normal	0.90801502	-0.032033476	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	K10661|0|ggo:101129287|MARCH6; E3 ubiquitin-protein ligase MARCH6; K10661 E3 ubiquitin-protein ligase MARCH6 [EC:6.3.2.19] (A)	Protein processing in endoplasmic reticulum (ko04141)	[A]	RNA processing and modification	RING-variant domain	E3 ubiquitin-protein ligase MARCH6 GN=MARCH6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MARCH6 [Oryctolagus cuniculus]
ENSG00000145506(NKD2)	--	7.460531036	304	3.154611451	137	5.7673326	238	2.925335911	121	3.321250289	131	1.5343921	78	6.13E-08	-1.348694788	down	0.965014783	-0.085075149	normal	2.15E-09	-1.599036345	down	0.075675262	-1.062889146	normal	--	--	--	K03213|0|ggo:101131815|NKD2; protein naked cuticle homolog 2; K03213 naked cuticle (A)	Wnt signaling pathway (ko04310)	--	--	--	Protein naked cuticle homolog 2 GN=NKD2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein naked cuticle homolog 2 [Eptesicus fuscus]
ENSG00000145526(CDH18)	--	0	0	0	0	0	0	0.090809883	5	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06805|0|pps:100977350|CDH18; cadherin 18, type 2; K06805 cadherin 18, type 2 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-18 (Precursor) GN=CDH18 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: cadherin-18 [Pteropus alecto] 
ENSG00000145536(ADAMTS16)	--	1.25434586	115	1.489675822	125	1.23241775	98	1.255453248	89	1.419912881	111	0.993994912	90	0.90666184	-0.39457793	normal	0.956988031	-0.190349445	normal	0.96774548	-0.129069136	normal	0.623331118	-0.242380651	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: peptidase activity (GO:0008233);; 	"K08630|0|hsa:170690|ADAMTS16, ADAMTS16s; ADAM metallopeptidase with thrombospondin type 1 motif, 16; K08630 a disintegrin and metalloproteinase with thrombospondin motifs 16 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; Thrombospondin type 1 domain;; PLAC (protease and lacunin) domain;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 16 (Precursor) GN=ADAMTS16 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 16 [Ceratotherium simum simum]
ENSG00000145545(SRD5A1)	--	5.738232	644	5.464175	616	5.472025	605	6.103976	686	5.66121	636	5.819531	651	0.973237178	0.060176515	normal	0.973271635	0.024610396	normal	0.969952707	0.097196699	normal	0.84268147	0.059781026	normal	--	--	"Cellular Component: cytoplasm (GO:0005737);; Biological Process: lipid metabolic process (GO:0006629);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; "	"K12343|1.06811e-173|ptr:743740|SRD5A1; steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1); K12343 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:1.3.1.22] (A)"	Steroid hormone biosynthesis (ko00140)	[I]	Lipid transport and metabolism	3-oxo-5-alpha-steroid 4-dehydrogenase;; Protein of unknown function (DUF1295);; Phospholipid methyltransferase	3-oxo-5-alpha-steroid 4-dehydrogenase 1 GN=SRD5A1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 1 [Odobenus rosmarus divergens]
ENSG00000145555(MYO10)	--	35.52695954	6590	34.63155386	6294	36.70790152	6637	27.26553893	5105	35.78372976	6329	29.9681556	5316	0.858842572	-0.399093715	normal	0.99432683	-0.013422953	normal	0.947647518	-0.328397822	normal	0.184806308	-0.241772095	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoskeleton (GO:0005856);; Biological Process: signal transduction (GO:0007165);; Cellular Component: myosin complex (GO:0016459);; 	K12559|0|hsa:4651|MYO10; myosin X; K12559 myosin X (A)	Fc gamma R-mediated phagocytosis (ko04666)	[N]	Cell motility	Myosin head (motor domain);; MyTH4 domain;; PH domain;; FERM central domain;; Pleckstrin homology domain;; Pleckstrin homology domain;; PH domain;; IQ calmodulin-binding motif;; Ras association (RalGDS/AF-6) domain	Unconventional myosin-X GN=MYO10 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: unconventional myosin-X isoform X1 [Oryctolagus cuniculus]
ENSG00000145569(FAM105A)	--	2.757551	193	2.088278	145	1.993575	137	2.826583	207	2.398245	175	1.728172	111	0.965185529	0.069662135	normal	0.939235245	0.247522758	normal	0.93069618	-0.308121851	normal	0.971083755	0.030439973	normal	--	--	--	--	--	--	--	--	Inactive ubiquitin thioesterase FAM105A GN=FAM105A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: inactive ubiquitin thioesterase FAM105A [Sus scrofa]
ENSG00000145592(RPL37)	--	300.8239302	7701	282.6955847	8145	311.0175509	7723	387.9202027	9206	313.69995	8111	325.2582832	8386	0.987365387	0.226654982	normal	0.995317798	-0.027456354	normal	0.994193057	0.110509245	normal	0.666893674	0.103471951	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02922|7.46021e-57|hgl:101722662|Rpl37; ribosomal protein L37; K02922 large subunit ribosomal protein L37e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L37e	60S ribosomal protein L37 GN=RPL37 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: ribosomal protein L37 [Capra hircus]
ENSG00000145604(SKP2)	--	9.655118474	414	12.07143132	510	8.526644019	408	12.99875379	623	13.14547978	583	10.75888008	476	0.198862598	0.55707337	normal	0.956107023	0.171097289	normal	0.942556634	0.213368113	normal	0.1434328	0.314364451	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03875|0|mcf:102114882|SKP2; S-phase kinase-associated protein 2, E3 ubiquitin protein ligase; K03875 F-box and leucine-rich repeat protein 1 (S-phase kinase-associated protein 2) (A)"	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Ubiquitin mediated proteolysis (ko04120);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Small cell lung cancer (ko05222)	[O]	"Posttranslational modification, protein turnover, chaperones"	F-box-like;; F-box domain	S-phase kinase-associated protein 2 GN=SKP2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: S-phase kinase-associated protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000145623(OSMR)	--	56.7749	5061	50.40551	4457	51.12617	4673	65.36776	6181	58.89526	5406	71.23386	6720	0.976386201	0.257514695	normal	0.974337657	0.256982717	normal	0.393819147	0.515680846	normal	0.035169427	0.346413518	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05057|0|ptr:461908|OSMR; oncostatin M receptor; K05057 oncostatin M receptor (A)	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630)	--	--	Fibronectin type III domain	Oncostatin-M-specific receptor subunit beta (Precursor) GN=OSMR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: oncostatin-M-specific receptor subunit beta isoform X1 [Equus caballus]
ENSG00000145632(PLK2)	--	49.217369	2786	64.99432151	3680	65.7038	3702	114.822031	6528	115.699403	6542	115.305097	6556	3.89E-11	1.197169757	up	0.000318504	0.808347025	normal	0.000167805	0.815965689	normal	2.34E-11	0.927751028	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08861|0|pps:100968426|PLK2; polo-like kinase 2; K08861 polo-like kinase 2 [EC:2.7.11.21] (A)	FoxO signaling pathway (ko04068)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; POLO box duplicated region;; Protein tyrosine kinase	Serine/threonine-protein kinase PLK2 GN=PLK2 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase PLK2 [Felis catus]
ENSG00000145642(FAM159B)	--	0	0	0.0750398	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Wnt and FGF inhibitory regulator	Membrane protein FAM159B GN=FAM159B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: membrane protein FAM159B [Bison bison bison]
ENSG00000145675(PIK3R1)	--	5.173228989	541	3.670287425	445	4.751275552	532	5.03692067	612	4.680378063	556	3.6735879	416	0.962197074	0.146678979	normal	0.893279204	0.29894251	normal	0.813049289	-0.361967515	normal	0.923805752	0.039298667	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K02649|0|pps:100994315|PIK3R1; phosphoinositide-3-kinase, regulatory subunit 1 (alpha); K02649 phosphoinositide-3-kinase, regulatory subunit (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; Carbohydrate digestion and absorption (ko04973);; Bacterial invasion of epithelial cells (ko05100);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	SH2 domain;; RhoGAP domain;; SH3 domain;; Variant SH3 domain	Phosphatidylinositol 3-kinase regulatory subunit alpha GN=PIK3R1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1 [Lipotes vexillifer]
ENSG00000145685(LHFPL2)	--	21.116298	1759	21.7281149	1817	20.57871319	1703	26.08621448	2192	27.94871851	2324	31.17981872	2607	0.936035929	0.286435566	normal	0.89783973	0.333379206	normal	0.052531663	0.605582869	normal	0.006332299	0.411460538	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Lipoma HMGIC fusion partner-like protein	Lipoma HMGIC fusion partner-like 2 protein GN=LHFPL2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: lipoma HMGIC fusion partner-like 2 protein [Orycteropus afer afer]
ENSG00000145687(SSBP2)	--	6.57101432	155	4.312530887	103	6.45781545	135	9.133625751	197	6.583852663	153	4.805583147	134	0.912030572	0.312343562	normal	0.687377315	0.54288231	normal	0.968353045	-0.018806392	normal	0.485544784	0.278226198	normal	--	--	--	--	--	[LKR]	"Replication, recombination and repair;; Transcription;; General function prediction only"	"Single-stranded DNA binding protein, SSDP"	Single-stranded DNA-binding protein 2 GN=SSBP2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: single-stranded DNA-binding protein 2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000145700(ANKRD31)	--	0.12793569	16	0.261114736	33	0.296498553	37	0.095737526	12	0.059295119	7	0.069880432	9	--	--	--	0.028165693	-2.038545996	normal	0.031016044	-1.880774435	normal	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies)	Putative ankyrin repeat domain-containing protein 31 GN=ANKRD31 OS=Homo sapiens (Human) PE=5 SV=2	R	General function prediction only	PREDICTED: putative ankyrin repeat domain-containing protein 31 isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000145703(IQGAP2)	--	9.103603844	1186	5.106234576	663	6.005992307	716	1.050072451	131	2.506086266	325	2.517174525	321	0	-3.194144038	down	2.44E-06	-1.046511144	down	3.22E-08	-1.161912673	down	0.00254973	-1.742035186	down	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of GTPase activity (GO:0043087);; 	K05767|0|ggo:101144088|IQGAP2; ras GTPase-activating-like protein IQGAP2; K05767 Ras GTPase-activating-like protein IQGAP2/3 (A)	Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; RasGAP C-terminus;; IQ calmodulin-binding motif;; Calponin homology (CH) domain	Ras GTPase-activating-like protein IQGAP2 GN=IQGAP2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating-like protein IQGAP2 [Ceratotherium simum simum]
ENSG00000145715(RASA1)	--	14.00572257	1153	14.59700959	1209	15.06012118	1190	12.48442483	1026	13.06498	1071	11.14939454	889	0.960225503	-0.198912842	normal	0.961772429	-0.196021615	normal	0.627391041	-0.428365546	normal	0.123619329	-0.271962171	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of GTPase activity (GO:0043087);; 	"K04352|0|hsa:5921|RASA1, CM-AVM, CMAVM, GAP, PKWS, RASA, RASGAP, p120GAP, p120RASGAP; RAS p21 protein activator (GTPase activating protein) 1; K04352 Ras GTPase-activating protein 1 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Axon guidance (ko04360)	[R]	General function prediction only	SH2 domain;; GTPase-activator protein for Ras-like GTPase;; PH domain;; SH3 domain;; C2 domain	Ras GTPase-activating protein 1 GN=RASA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating protein 1 [Odobenus rosmarus divergens]
ENSG00000145721(LIX1)	--	0	0	0	0	0.0301744	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Limb expression 1	Protein limb expression 1 homolog GN=LIX1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein limb expression 1 homolog [Sus scrofa] 
ENSG00000145723(GIN1)	--	2.09209207	113	1.7395811	92	2.49648	85	2.572154	115	2.752895	113	2.647425	134	0.969819591	-0.005447752	normal	0.946672937	0.271162731	normal	0.538014267	0.639273999	normal	0.512876976	0.298907491	normal	[L]	"Replication, recombination and repair"	--	--	--	[R]	General function prediction only	Integrase core domain;; His(2)-Cys(2) zinc finger	Gypsy retrotransposon integrase-like protein 1 GN=GIN1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: gypsy retrotransposon integrase-like protein 1 isoform X2 [Canis lupus familiaris] 
ENSG00000145725(PPIP5K2)	--	12.00589366	970	14.27284021	1060	19.60180651	1094	18.54100474	1272	14.71706862	1061	15.09701782	1087	0.82156545	0.359710927	normal	0.979633333	-0.020037593	normal	0.980498369	-0.017527932	normal	0.632235429	0.108987244	normal	--	--	Molecular Function: acid phosphatase activity (GO:0003993);; 	"K13024|0|ptr:461976|PPIP5K2, HISPPD1; diphosphoinositol pentakisphosphate kinase 2; K13024 inositol hexakisphosphate/diphosphoinositol-pentakisphosphate kinase [EC:2.7.4.21 2.7.4.24] (A)"	--	[Z]	Cytoskeleton	Histidine phosphatase superfamily (branch 2);; RimK-like ATP-grasp domain	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 GN=PPIP5K2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 isoform X2 [Equus caballus]
ENSG00000145730(PAM)	--	87.96210521	3433	76.93417435	2988	76.85345172	2834	96.66850762	3698	81.72409431	3024	92.41295961	3285	0.990352305	0.076410152	normal	0.989956047	-0.00414648	normal	0.977612895	0.204660647	normal	0.689284357	0.090883811	normal	[S]	Function unknown	"Molecular Function: monooxygenase activity (GO:0004497);; Molecular Function: copper ion binding (GO:0005507);; Molecular Function: protein binding (GO:0005515);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen (GO:0016715);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00504|0|hsa:5066|PAM, PAL, PHM; peptidylglycine alpha-amidating monooxygenase (EC:1.14.17.3 4.3.2.5); K00504 peptidylglycine monooxygenase [EC:1.14.17.3] K18200 peptidylamidoglycolate lyase [EC:4.3.2.5] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Copper type II ascorbate-dependent monooxygenase, C-terminal domain;; NHL repeat;; Copper type II ascorbate-dependent monooxygenase, N-terminal domain"	Peptidyl-alpha-hydroxyglycine alpha-amidating lyase (Precursor) GN=PAM OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-glycine alpha-amidating monooxygenase isoform 1 [Ceratotherium simum simum]
ENSG00000145734(BDP1)	--	6.786965	1711	7.758810003	1944	7.935030876	1943	7.702711	1950	7.450857	1869	6.96255	1749	0.977388062	0.157669415	normal	0.984377854	-0.078126218	normal	0.977255748	-0.159915799	normal	0.917111848	-0.029177991	normal	--	--	--	"K15198|0|hsa:55814|BDP1, HSA238520, TAF3B1, TFC5, TFIIIB'', TFIIIB150, TFIIIB90, TFNR; B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB; K15198 transcription factor TFIIIB component B'' (A)"	--	[K]	Transcription	--	Transcription factor TFIIIB component B'' homolog GN=BDP1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor TFIIIB component B'' homolog [Dasypus novemcinctus]
ENSG00000145736(GTF2H2)	--	5.74902704	226	4.851292	218	4.5918975	207	6.491205625	269	5.408073	246	5.530529	227	0.941475205	0.219084664	normal	0.955511219	0.151911152	normal	0.960639752	0.123905402	normal	0.639651132	0.166938129	normal	[KL]	"Transcription;; Replication, recombination and repair"	Biological Process: DNA repair (GO:0006281);; Molecular Function: zinc ion binding (GO:0008270);; 	"K03142|0|hsa:2966|GTF2H2, BTF2, BTF2P44, T-BTF2P44, TFIIH, p44; general transcription factor IIH, polypeptide 2, 44kDa; K03142 transcription initiation factor TFIIH subunit 2 (A)"	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420);; Viral carcinogenesis (ko05203)	[KL]	"Transcription;; Replication, recombination and repair"	Ssl1-like;; TFIIH C1-like domain;; von Willebrand factor type A domain	General transcription factor IIH subunit 2 GN=GTF2H2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor IIH subunit 2 [Loxodonta africana]
ENSG00000145740(SLC30A5)	--	25.7414681	1390	29.32262281	1553	31.032935	1466	27.97269025	1466	25.77145822	1303	28.93108236	1548	0.982851827	0.045918533	normal	0.934656393	-0.274355203	normal	0.98256631	0.070158488	normal	0.843804337	-0.051533372	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14692|0|nle:100606665|SLC30A5; solute carrier family 30 (zinc transporter), member 5; K14692 solute carrier family 30 (zinc transporter), member 5/7 (A)"	--	[P]	Inorganic ion transport and metabolism	Cation efflux family	Zinc transporter 5 GN=SLC30A5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	"PREDICTED: zinc transporter 5, partial [Tupaia chinensis]"
ENSG00000145741(BTF3)	--	428.4769149	6294	439.553202	6458	448.9861314	6573	491.7652462	7397	470.5851015	6865	463.1955012	6849	0.98801367	0.202085293	normal	0.994071871	0.066730564	normal	0.994500519	0.051038429	normal	0.649305813	0.106135107	normal	--	--	--	K01527|6.82365e-124|pps:100967391|BTF3; basic transcription factor 3; K01527 nascent polypeptide-associated complex subunit beta (A)	--	[K]	Transcription	NAC domain	Transcription factor BTF3 GN=BTF3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor BTF3 isoformX1 [Equus caballus]
ENSG00000145743(FBXL17)	--	10.25488508	590	10.76458463	676	9.74700671	588	8.923993694	579	8.340786575	546	8.868965998	574	0.971895791	-0.057831839	normal	0.862192302	-0.328728822	normal	0.972607998	-0.042945066	normal	0.554702225	-0.147353252	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10283|0|hsa:64839|FBXL17, FBXO13, Fbl17, Fbx13; F-box and leucine-rich repeat protein 17; K10283 F-box and leucine-rich repeat protein 17 (A)"	--	[R]	General function prediction only	F-box-like;; Leucine Rich repeat;; F-box domain;; Leucine Rich repeats (2 copies)	F-box/LRR-repeat protein 17 GN=FBXL17 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 17 [Ceratotherium simum simum]
ENSG00000145757(SPATA9)	--	0.0627058	1	0.125515	2	0	0	0.181122	3	0.0606789	0	0.121854	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Spermatogenesis-associated protein 9 GN=SPATA9 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	spermatogenesis-associated protein 9 [Sus scrofa] 
ENSG00000145777(TSLP)	--	0.056302683	2	0.0856338	3	0.142469153	4	0.055795434	2	0.0270736	0	0.083238259	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine activity (GO:0005125);; 	K05436|2.10456e-108|hsa:85480|TSLP; thymic stromal lymphopoietin; K05436 thymic stromal lymphopoietin (A)	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	Thymic stromal lymphopoietin	Thymic stromal lymphopoietin (Precursor) GN=TSLP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: thymic stromal lymphopoietin [Galeopterus variegatus]
ENSG00000145779(TNFAIP8)	--	16.15092121	432	23.95930425	533	21.9008652	542	41.17331583	1091	33.34710258	878	37.48872029	896	2.32E-11	1.302700204	up	0.012227506	0.697102791	normal	0.006457891	0.715346116	normal	2.58E-08	0.905156679	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF758)	Tumor necrosis factor alpha-induced protein 8 GN=TNFAIP8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor alpha-induced protein 8 isoform X2 [Galeopterus variegatus]
ENSG00000145780(FEM1C)	--	5.90583	469	6.46427	515	6.70588	523	7.81706	627	7.09815	563	7.94166	632	0.757402237	0.386945662	normal	0.966442188	0.106835822	normal	0.920296874	0.264126438	normal	0.243212099	0.252720856	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Protein fem-1 homolog C GN=FEM1C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	protein fem-1 homolog C [Bos taurus] 
ENSG00000145781(COMMD10)	--	27.098358	551	29.446956	570	30.395508	585	24.266823	485	27.2992622	550	22.74221	442	0.943306245	-0.214262452	normal	0.969894102	-0.072760321	normal	0.699642446	-0.411453874	normal	0.313582656	-0.229241734	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 10 GN=COMMD10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COMM domain-containing protein 10 isoform X1 [Equus caballus]
ENSG00000145782(ATG12)	--	16.23207145	811	17.85135	887	18.77047146	885	21.98715105	1007	17.69420159	826	18.241	854	0.915917769	0.28097915	normal	0.970458452	-0.123999739	normal	0.976583545	-0.059629093	normal	0.904901829	0.035240273	normal	--	--	Biological Process: autophagic vacuole assembly (GO:0000045);; Cellular Component: cytoplasm (GO:0005737);; 	K08336|2.61568e-79|tup:102481748|ATG12; autophagy related 12; K08336 ubiquitin-like protein ATG12 (A)	FoxO signaling pathway (ko04068);; Regulation of autophagy (ko04140);; RIG-I-like receptor signaling pathway (ko04622)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-like autophagy protein Apg12;; Autophagy protein Atg8 ubiquitin like	Ubiquitin-like protein ATG12 GN=ATG12 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like protein ATG12 [Tupaia chinensis]
ENSG00000145794(MEGF10)	--	0.024687218	2	0.024577002	1	0	0	0	0	0	0	0.025130392	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin EGF-like (Domains III and V);; Human growth factor-like EGF;; EGF-like domain	Multiple epidermal growth factor-like domains protein 10 (Precursor) GN=MEGF10 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: multiple EGF-like-domains 10 [Equus caballus]
ENSG00000145817(YIPF5)	--	28.47704476	1194	31.27180907	1259	25.14788308	1096	29.74418727	1277	32.37581082	1353	32.2242419	1275	0.980423585	0.066041247	normal	0.979810001	0.082361555	normal	0.958799265	0.209689515	normal	0.596312297	0.116541217	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: membrane (GO:0016020);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Yip1 domain	Protein YIPF5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein YIPF5 [Felis catus] 
ENSG00000145819(ARHGAP26)	--	17.49941573	2237	10.52115874	1421	16.45490711	1917	11.03292552	1522	10.66590364	1417	8.267434617	1124	0.077996865	-0.585937921	normal	0.982862746	-0.025466214	normal	0.000604489	-0.777688801	normal	0.150357672	-0.478297738	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; IRSp53/MIM homology domain	Rho GTPase-activating protein 26 GN=ARHGAP26 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 26 isoform 1 [Ceratotherium simum simum]
ENSG00000145826(LECT2)	--	0.0654794	1	0	0	0.567849777	6	0	0	0.126936049	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Peptidase family M23	Leukocyte cell-derived chemotaxin-2 (Precursor) GN=LECT2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leukocyte cell-derived chemotaxin-2 [Pteropus alecto] 
ENSG00000145832(SLC25A48)	--	0	0	0	0	0	0	0	0	0	0	0.0622059	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15124|1.49243e-160|ptr:471641|SLC25A48; solute carrier family 25, member 48; K15124 solute carrier family 25, member 48 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 48 GN=SLC25A48 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 48 isoform X4 [Tupaia chinensis]
ENSG00000145833(DDX46)	--	51.028264	4408	55.90947691	5379	51.30277116	4964	52.23064719	4975	49.44441887	4763	50.70828875	4791	0.98940789	0.143692875	normal	0.985382323	-0.196835145	normal	0.992768923	-0.059449307	normal	0.877074375	-0.043206136	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	K12811|0|ptr:462070|DDX46; DEAD (Asp-Glu-Ala-Asp) box polypeptide 46; K12811 ATP-dependent RNA helicase DDX46/PRP5 [EC:3.6.4.13] (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX46 GN=DDX46 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX46 isoform X1 [Capra hircus]
ENSG00000145850(TIMD4)	--	1.135322	26	0.908050361	25	0.530684205	14	1.633147551	46	1.782707005	49	1.142890966	33	0.877038548	0.758217256	normal	0.718706487	0.909478518	normal	0.743129996	1.145993024	normal	0.095530812	0.954687343	normal	--	--	--	--	--	--	--	Immunoglobulin V-set domain	T-cell immunoglobulin and mucin domain-containing protein 4 (Precursor) GN=TIMD4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: T-cell immunoglobulin and mucin domain-containing protein 4 [Tupaia chinensis]
ENSG00000145860(RNF145)	--	51.804345	2815	61.1564148	3466	49.2551143	2770	68.2502753	3897	78.75687	4316	86.994243	4815	0.683970783	0.438192698	normal	0.95457195	0.294881155	normal	0.000372546	0.789027564	normal	0.003372224	0.504658101	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"TRC8 N-terminal domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 145 GN=RNF145 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 145 [Galeopterus variegatus]
ENSG00000145861(C1QTNF2)	--	0.065462	3	0.17077	8	0.0842504	3	0.195048	9	0.190328	8	0.1723	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	Complement C1q tumor necrosis factor-related protein 2 (Precursor) GN=C1QTNF2 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: complement C1q tumor necrosis factor-related protein 2 [Orycteropus afer afer]
ENSG00000145868(FBXO38)	--	8.56040027	678	9.669962054	786	9.427739782	740	8.761350179	710	8.651345463	718	9.334960268	770	0.974759024	0.035622603	normal	0.96444559	-0.151666577	normal	0.975371218	0.048943674	normal	0.942531704	-0.024893512	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10313|0|ptr:462174|FBXO38; F-box protein 38; K10313 F-box protein 38 (A)	--	--	--	F-box domain	F-box only protein 38 GN=FBXO38 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	F-box only protein 38 [Bos taurus] 
ENSG00000145882(PCYOX1L)	--	5.997474741	271	4.071211349	182	5.527595114	250	3.54278345	158	3.980457333	177	3.282382568	146	0.016560303	-0.803159896	normal	0.964622002	-0.061100799	normal	0.033554623	-0.77801776	normal	0.039102426	-0.568564248	normal	--	--	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor (GO:0016670);; Biological Process: prenylcysteine catabolic process (GO:0030328);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	--	--	Prenylcysteine lyase;; NAD(P)-binding Rossmann-like domain	Prenylcysteine oxidase-like (Precursor) GN=PCYOX1L OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prenylcysteine oxidase-like [Trichechus manatus latirostris]
ENSG00000145888(GLRA1)	--	0	0	0	0	0	0	0	0	0.0311748	0	0.0317141	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05193|0|phd:102320782|GLRA1; glycine receptor, alpha 1; K05193 glycine receptor alpha-1 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Glycine receptor subunit alpha-1 (Precursor) GN=GLRA1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: glycine receptor subunit alpha-1 isoform X1 [Physeter catodon]
ENSG00000145901(TNIP1)	--	56.02106292	3468	52.49351472	3349	46.98921593	3298	75.180255	4680	64.223243	3831	87.66095855	5424	0.82097169	0.401418787	normal	0.9841795	0.172491224	normal	0.004328485	0.709218189	normal	0.043982703	0.44133941	normal	--	--	--	--	--	--	--	--	TNFAIP3-interacting protein 1 GN=TNIP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TNFAIP3-interacting protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000145907(G3BP1)	--	71.45622	4837	73.102628	4896	77.624946	4815	108.453538	7743	107.081417	7318	93.064333	5961	0.027870041	0.647783845	normal	0.237479852	0.558277374	normal	0.960708785	0.299642399	normal	0.000822877	0.509128843	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	K17265|0|pps:100987865|G3BP1; GTPase activating protein (SH3 domain) binding protein 1; K17265 Ras GTPase-activating protein-binding protein 1 [EC:3.6.4.12 3.6.4.13] (A)	--	[T]	Signal transduction mechanisms	"Nuclear transport factor 2 (NTF2) domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Ras GTPase-activating protein-binding protein 1 GN=G3BP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating protein-binding protein 1 [Felis catus] 
ENSG00000145908(ZNF300)	--	3.632914155	256	3.24228364	236	3.700026733	263	5.409342161	387	5.7423009	403	5.3739967	376	0.281318848	0.562593926	normal	0.017301528	0.746863075	normal	0.476920886	0.504937727	normal	0.005131397	0.605913297	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:91975|ZNF300; zinc finger protein 300; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; TFIIH C1-like domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 300 GN=ZNF300 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 300 isoform X1 [Felis catus] 
ENSG00000145911(N4BP3)	--	0.794826	102	0.327153	43	0.425152402	53	0.3622727	48	0.350052	44	0.241377145	33	0.023327413	-1.093701329	normal	0.979463885	0.011345848	normal	0.884240679	-0.667466123	normal	0.401740807	-0.686156558	normal	--	--	--	--	--	--	--	Fez1	NEDD4-binding protein 3 GN=N4BP3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: NEDD4-binding protein 3 [Ceratotherium simum simum]
ENSG00000145912(NHP2)	--	162.4110111	2000	183.30453	2251	196.6305574	2357	166.7023794	2042	167.1244007	1936	149.3109237	1831	0.98697245	-0.000848752	normal	0.961733975	-0.238740519	normal	0.831532678	-0.372339607	normal	0.249239147	-0.20727737	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K11129|3.89141e-108|pps:100990295|NHP2; NHP2 ribonucleoprotein; K11129 H/ACA ribonucleoprotein complex subunit 2 (A)	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	H/ACA ribonucleoprotein complex subunit 2 GN=NHP2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: H/ACA ribonucleoprotein complex subunit 2 [Ailuropoda melanoleuca] 
ENSG00000145916(RMND5B)	--	14.846496	554	13.4035996	548	14.97330756	545	14.64117005	566	14.650236	575	18.05039306	660	0.972906907	8.36E-05	normal	0.971292348	0.047830643	normal	0.918743249	0.267243528	normal	0.693531036	0.108202653	normal	[R]	General function prediction only	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	CTLH/CRA C-terminal to LisH motif domain;; RING-type zinc-finger	Protein RMD5 homolog B GN=RMND5B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein RMD5 homolog B [Chrysochloris asiatica] 
ENSG00000145919(BOD1)	--	38.30537782	1031	41.35071473	1163	39.790608	1088	39.50949419	1102	39.13292412	1084	45.59340168	1280	0.978703292	0.065153708	normal	0.974457345	-0.122747526	normal	0.953212284	0.225884049	normal	0.828576192	0.057896403	normal	--	--	--	--	--	--	--	COMPASS (Complex proteins associated with Set1p) component shg1	Biorientation of chromosomes in cell division protein 1 GN=BOD1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: biorientation of chromosomes in cell division protein 1-like [Myotis lucifugus]
ENSG00000145920(CPLX2)	--	2.3656694	221	3.3675919	259	2.807747566	216	4.753321106	488	12.09083071	1086	10.635328	987	1.54E-06	1.106697078	up	0	2.040258895	up	0	2.175905715	up	0.002825147	1.860131859	up	--	--	Biological Process: neurotransmitter transport (GO:0006836);; Molecular Function: syntaxin binding (GO:0019905);; 	K15294|3.68074e-55|umr:103664769|CPLX2; complexin 2; K15294 complexin-1/2 (A)	Synaptic vesicle cycle (ko04721)	--	--	Synaphin protein	Complexin-2 GN=CPLX2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: complexin-2 [Erinaceus europaeus]
ENSG00000145934(TENM2)	--	0.042740898	8	0.022980726	4	0.070650545	13	0.046458914	9	0.028111547	4	0.025505527	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Teneurin Intracellular Region;; GHH signature containing HNH/Endo VII superfamily nuclease toxin;; EGF-like domain;; NHL repeat;; RHS Repeat;; Human growth factor-like EGF	Ten-2 intracellular domain GN=TENM2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: teneurin-2 isoform X1 [Oryctolagus cuniculus] 
ENSG00000145945(FAM50B)	--	5.80315	174	4.74775	150	4.7833	148	3.40895	102	3.70341	110	4.63362	137	0.084290089	-0.792100283	normal	0.811768897	-0.463406445	normal	0.963646235	-0.118454336	normal	0.196523513	-0.455993241	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K13119|0|hsa:26240|FAM50B, D6S2654E, X5L; family with sequence similarity 50, member B; K13119 protein FAM50 (A)"	--	[S]	Function unknown	"XAP5, circadian clock regulator"	Protein FAM50B GN=FAM50B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM50B [Odobenus rosmarus divergens]
ENSG00000145949(MYLK4)	--	0.114339517	12	0.184743186	18	0.081886967	7	0.030937668	3	0.090776319	8	0.161165207	17	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K00907|0|hsa:340156|MYLK4, SgK085; myosin light chain kinase family, member 4 (EC:2.7.11.1); K00907 myosin-light-chain kinase [EC:2.7.11.18] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Myosin light chain kinase family member 4 GN=MYLK4 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: myosin light chain kinase family member 4 isoform X1 [Tupaia chinensis]
ENSG00000145979(TBC1D7)	--	16.52123	231	19.7131836	308	17.5897662	282	26.4564353	396	22.8367141	343	34.93085444	511	0.01730819	0.742959372	normal	0.95872159	0.133231567	normal	0.000966192	0.845918233	normal	0.054555449	0.586023247	normal	--	--	--	--	--	--	--	Rab-GTPase-TBC domain	TBC1 domain family member 7 GN=TBC1D7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: TBC1 domain family member 7 isoformX1 [Equus caballus] 
ENSG00000145982(FARS2)	--	9.351839792	258	9.82828368	265	10.17877192	288	9.442984	268	10.137764	299	10.76061106	314	0.967051013	0.023890084	normal	0.955366054	0.151910075	normal	0.961718418	0.115821695	normal	0.791452383	0.098917634	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: tRNA binding (GO:0000049);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: tRNA aminoacylation (GO:0043039);; 	"K01889|0|hsa:10667|FARS2, COXPD14, FARS1, HSPC320, PheRS, dJ520B18.2; phenylalanyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.20); K01889 phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class II core domain (F);; Ferredoxin-fold anticodon binding domain	"Phenylalanine--tRNA ligase, mitochondrial (Precursor) GN=FARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: phenylalanine--tRNA ligase, mitochondrial [Galeopterus variegatus] "
ENSG00000145990(GFOD1)	--	1.711305974	228	1.534585855	189	1.417692713	180	1.878951286	251	2.473160894	338	2.623028824	358	0.962206575	0.107133066	normal	0.008344441	0.812285933	normal	0.000185899	0.977734399	normal	0.013265344	0.645321899	normal	[R]	General function prediction only	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[R]	General function prediction only	"Oxidoreductase family, NAD-binding Rossmann fold;; Oxidoreductase family, C-terminal alpha/beta domain"	Glucose-fructose oxidoreductase domain-containing protein 1 (Precursor) GN=GFOD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: glucose-fructose oxidoreductase domain-containing protein 1 isoform X1 [Felis catus]
ENSG00000145996(CDKAL1)	--	3.950142586	181	6.179719341	252	5.658844397	255	4.878911507	204	4.098025	173	4.926511	231	0.959179938	0.140622395	normal	0.437757007	-0.559996862	normal	0.956932287	-0.149961012	normal	0.575238441	-0.198988577	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; Molecular Function: 4 iron, 4 sulfur cluster binding (GO:0051539);; "	K15865|0|hsa:54901|CDKAL1; CDK5 regulatory subunit associated protein 1-like 1 (EC:2.8.4.5); K15865 threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5] (A)	--	[R]	General function prediction only	Uncharacterized protein family UPF0004;; Radical SAM superfamily;; TRAM domain	Threonylcarbamoyladenosine tRNA methylthiotransferase GN=CDKAL1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: threonylcarbamoyladenosine tRNA methylthiotransferase isoform X1 [Sus scrofa] 
ENSG00000146005(PSD2)	--	0.0218366	2	0	0	0.0104882	0	0	0	0.0213073	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K12494|0|hsa:84249|PSD2, EFA6C; pleckstrin and Sec7 domain containing 2; K12494 PH and SEC7 domain-containing protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; Pleckstrin homology domain;; PH domain	PH and SEC7 domain-containing protein 2 GN=PSD2 OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PH and SEC7 domain-containing protein 2 [Equus przewalskii]
ENSG00000146006(LRRTM2)	--	0.062145471	6	0.0506386	2	0.042036101	3	0.041399	4	0.0594812	5	0.0583773	5	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K16665|0|ptr:746417|LRRTM2; leucine rich repeat transmembrane neuronal 2; K16665 leucine-rich repeat transmembrane neuronal protein 1/2 (A)	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine-rich repeat;; Leucine rich repeat	Leucine-rich repeat transmembrane neuronal protein 2 (Precursor) GN=LRRTM2 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: leucine-rich repeat transmembrane neuronal protein 2 [Tupaia chinensis]
ENSG00000146013(GFRA3)	--	0.0534125	2	0.030285567	1	0.05917588	1	0.0267096	1	0.030104641	0	0.061052825	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GDNF/GAS1 domain	GDNF family receptor alpha-3 (Precursor) GN=GFRA3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: GDNF family receptor alpha-3 [Galeopterus variegatus]
ENSG00000146021(KLHL3)	--	0.487487292	56	0.541714335	63	0.351183498	40	0.331412177	37	0.323369079	38	0.6326822	73	0.901598308	-0.608058206	normal	0.778688614	-0.728037992	normal	0.544575393	0.835883636	normal	0.894915588	-0.123243421	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10443|0|ggo:101143955|KLHL3; kelch-like protein 3 isoform 1; K10443 kelch-like protein 2/3 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 3 GN=KLHL3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 3 [Condylura cristata]
ENSG00000146038(DCDC2)	--	15.991374	1039	16.0712864	1193	19.66249241	1264	11.86582732	734	15.43763203	686	24.32125686	1168	0.222121465	-0.531236043	normal	0.000393623	-0.818353718	normal	0.97606718	-0.122095623	normal	0.179658141	-0.453468916	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Doublecortin	Doublecortin domain-containing protein 2 GN=DCDC2 OS=Homo sapiens (Human) PE=1 SV=2	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: doublecortin domain-containing protein 2 [Trichechus manatus latirostris]
ENSG00000146049(KAAG1)	--	9.00799	194	10.4236	226	8.63577	188	6.04063	132	6.30596	136	8.60635	189	0.484274687	-0.580737636	normal	0.073393346	-0.747621449	normal	0.967082495	-0.000632793	normal	0.167520969	-0.432226238	normal	--	--	--	--	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Kidney-associated antigen 1	Kidney-associated antigen 1 GN=KAAG1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: kidney-associated antigen 1 [Galeopterus variegatus]
ENSG00000146054(TRIM7)	--	14.67670832	332	17.52187902	313	18.52093349	390	11.42109771	244	10.2291827	202	10.36116298	209	0.605470163	-0.472571963	normal	0.134349528	-0.649295911	normal	0.000649123	-0.903398785	normal	0.002106362	-0.681432548	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K12000|0|ptr:741704|TRIM7; tripartite motif containing 7; K12000 tripartite motif-containing protein 7 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 7 GN=TRIM7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 7 isoform X2 [Oryctolagus cuniculus]
ENSG00000146063(TRIM41)	--	11.742571	867	12.59502292	977	13.114406	1010	10.25869887	758	12.227406	886	14.62452167	1098	0.94597234	-0.224240996	normal	0.965815581	-0.162214619	normal	0.975168642	0.11207034	normal	0.823164267	-0.077686723	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: intracellular (GO:0005622);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; Molecular Function: metal ion binding (GO:0046872);; 	"K12017|0|hsa:90933|TRIM41, RINCK; tripartite motif containing 41; K12017 tripartite motif-containing protein 41 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY-associated domain;; SPRY domain;; zinc finger of C3HC4-type, RING;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Protein of unknown function (DUF3631)"	E3 ubiquitin-protein ligase TRIM41 GN=TRIM41 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM41 [Condylura cristata]
ENSG00000146066(HIGD2A)	--	122.831	856	144.05	1018	135.868	969	115.587	822	112.769	789	134.566	954	0.974164759	-0.089141369	normal	0.758509102	-0.388409541	normal	0.978810653	-0.030750474	normal	0.419819814	-0.169201248	normal	--	--	--	--	--	[R]	General function prediction only	Hypoxia induced protein conserved region	"HIG1 domain family member 2A, mitochondrial GN=HIGD2A OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	PREDICTED: HIG1 domain family member 2A-like [Myotis brandtii] 
ENSG00000146067(FAM193B)	--	5.162395909	410	6.111690563	457	5.300089731	442	5.830799708	449	6.013945133	421	7.542622168	565	0.96555758	0.099901467	normal	0.959914263	-0.139319976	normal	0.838935344	0.344866933	normal	0.707137971	0.112064688	normal	--	--	--	--	--	--	--	--	Protein FAM193B GN=FAM193B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM193B isoform X4 [Galeopterus variegatus]
ENSG00000146070(PLA2G7)	--	0.216385765	6	0.13244	4	0.0358864	0	0	0	0.105134	2	0.035637787	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: 1-alkyl-2-acetylglycerophosphocholine esterase activity (GO:0003847);; Biological Process: chlorophyll catabolic process (GO:0015996);; Biological Process: lipid catabolic process (GO:0016042);; Molecular Function: chlorophyllase activity (GO:0047746);; 	"K01062|0|hsa:7941|PLA2G7, LDL-PLA2, LP-PLA2, PAFAD, PAFAH; phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) (EC:3.1.1.47); K01062 platelet-activating factor acetylhydrolase [EC:3.1.1.47] (A)"	Ether lipid metabolism (ko00565)	[I]	Lipid transport and metabolism	"Platelet-activating factor acetylhydrolase, isoform II;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; Chlorophyllase enzyme;; Chlorophyllase;; Prolyl oligopeptidase family"	Platelet-activating factor acetylhydrolase (Precursor) GN=PLA2G7 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: platelet-activating factor acetylhydrolase isoform X1 [Equus caballus]
ENSG00000146072(TNFRSF21)	--	32.26443	2098	31.34381	2028	32.53583	2105	34.11116	2195	30.47143	1968	24.02522	1560	0.987220067	0.034349405	normal	0.985409127	-0.064705006	normal	0.611626814	-0.44019686	normal	0.50687409	-0.144827232	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K05157|0|hsa:27242|TNFRSF21, BM-018, CD358, DR6; tumor necrosis factor receptor superfamily, member 21; K05157 tumor necrosis factor receptor superfamily member 21 (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	Death domain;; TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 21 (Precursor) GN=TNFRSF21 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 21 [Trichechus manatus latirostris]
ENSG00000146083(RNF44)	--	16.362539	1346	18.73587	1491	16.574655	1379	14.023698	1114	14.96745	1191	19.34709	1538	0.905166955	-0.303380091	normal	0.860452686	-0.345140794	normal	0.975336321	0.148986825	normal	0.549364121	-0.153939831	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	RING finger protein 44 GN=RNF44 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 44 isoform 1 [Orcinus orca] 
ENSG00000146085(MUT)	--	7.438086119	432	5.398617685	344	6.858768854	372	6.575580912	381	7.091301044	392	8.039427086	452	0.942610705	-0.211271772	normal	0.95355599	0.166333169	normal	0.914099674	0.271725102	normal	0.834343569	0.072949317	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: intramolecular transferase activity (GO:0016866);; Molecular Function: cobalamin binding (GO:0031419);; Molecular Function: metal ion binding (GO:0046872);; 	"K01847|0|hsa:4594|MUT, MCM; methylmalonyl CoA mutase (EC:5.4.99.2); K01847 methylmalonyl-CoA mutase [EC:5.4.99.2] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)"	--	--	Methylmalonyl-CoA mutase;; B12 binding domain	"Methylmalonyl-CoA mutase, mitochondrial (Precursor) GN=MUT OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"RecName: Full=Methylmalonyl-CoA mutase, mitochondrial; Short=MCM; AltName: Full=Methylmalonyl-CoA isomerase; Flags: Precursor [Bos taurus] "
ENSG00000146090(RASGEF1C)	--	0.04390484	2	0.021704076	1	0.105398605	4	0.024002422	1	0	0	0.021615068	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif	Ras-GEF domain-containing family member 1C GN=RASGEF1C OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: ras-GEF domain-containing family member 1C [Elephantulus edwardii]
ENSG00000146094(DOK3)	--	1.724161556	40	2.761775389	78	1.576490793	55	2.22918342	65	3.015217371	84	3.540943444	97	0.851112257	0.64986061	normal	0.970443951	0.083920575	normal	0.404598561	0.793622228	normal	0.322245291	0.487649393	normal	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	--	--	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type)	Docking protein 3 GN=DOK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: docking protein 3 [Ursus maritimus]
ENSG00000146109(ABT1)	--	8.39255	392	7.52016	356	7.31442	343	9.59689	453	8.91381	416	8.48048	399	0.952727647	0.177178743	normal	0.944588147	0.202483392	normal	0.94327232	0.209033474	normal	0.470171857	0.1951851	normal	--	--	--	K14785|9.80416e-174|ptr:462499|ABT1; activator of basal transcription 1; K14785 ESF2/ABP1 family protein (A)	--	[K]	Transcription	--	Activator of basal transcription 1 GN=ABT1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: activator of basal transcription 1 [Canis lupus familiaris]
ENSG00000146112(PPP1R18)	--	11.900495	739	10.939247	780	11.78559	773	18.952482	1259	18.04859	1287	14.732711	1099	0.002629452	0.73661367	normal	0.008116525	0.699972578	normal	0.342766494	0.49853757	normal	1.32E-05	0.647789382	normal	--	--	Molecular Function: phosphatase binding (GO:0019902);; 	"K17559|0|hsa:170954|PPP1R18, HKMT1098, KIAA1949; protein phosphatase 1, regulatory subunit 18; K17559 phostensin (A)"	--	--	--	"Phostensin PP1-binding and SH3-binding region;; PP1-regulatory protein, Phostensin N-terminal"	Phostensin GN=PPP1R18 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phostensin [Galeopterus variegatus] 
ENSG00000146122(DAAM2)	--	0.011198	1	0.007197754	1	0.00711816	0	0	0	0.007161427	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	K04512|0|pps:100983888|DAAM2; dishevelled associated activator of morphogenesis 2; K04512 dishevelled associated activator of morphogenesis (A)	Wnt signaling pathway (ko04310)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain	Disheveled-associated activator of morphogenesis 2 GN=DAAM2 OS=Homo sapiens (Human) PE=2 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: disheveled-associated activator of morphogenesis 2 isoform X2 [Equus caballus] 
ENSG00000146143(PRIM2)	--	10.42532444	397	11.6611035	364	12.15081425	409	12.38600433	457	11.5756697	383	11.80510316	397	0.954119486	0.171603552	normal	0.967133502	0.051769697	normal	0.968694335	-0.051061635	normal	0.871241551	0.058803133	normal	[L]	"Replication, recombination and repair"	"Molecular Function: DNA primase activity (GO:0003896);; Biological Process: DNA replication, synthesis of RNA primer (GO:0006269);; "	"K02685|0|hsa:5558|PRIM2, PRIM2A, p58; primase, DNA, polypeptide 2 (58kDa) (EC:2.7.7.-); K02685 DNA primase large subunit [EC:2.7.7.-] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030)	[L]	"Replication, recombination and repair"	"Eukaryotic and archaeal DNA primase, large subunit"	DNA primase large subunit GN=PRIM2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA primase large subunit-like [Ceratotherium simum simum]
ENSG00000146147(MLIP)	--	0.069438494	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Muscular LMNA-interacting protein	Muscular LMNA-interacting protein GN=MLIP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: mucin-5AC-like isoform X1 [Leptonychotes weddellii]
ENSG00000146151(HMGCLL1)	--	0.6581522	20	0.129091012	5	0.32838009	11	0.914007647	30	0.960355784	33	0.7370095	26	0.972897457	0.521257983	normal	0.005758443	2.387406076	up	0.870318049	1.129168036	normal	0.041865243	1.284334381	normal	[E]	Amino acid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; 	K01640|0|mcf:102125219|HMGCLL1; 3-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1; K01640 hydroxymethylglutaryl-CoA lyase [EC:4.1.3.4] (A)	"Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Butanoate metabolism (ko00650);; Peroxisome (ko04146)"	[CE]	Energy production and conversion;; Amino acid transport and metabolism	HMGL-like	"3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic GN=HMGCLL1 OS=Homo sapiens (Human) PE=1 SV=3"	CE	Energy production and conversion;; Amino acid transport and metabolism	"PREDICTED: 3-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic isoform 2 [Sus scrofa]"
ENSG00000146166(LGSN)	--	16.23746937	1203	12.66667128	931	13.93013476	1097	10.50087023	809	8.999862327	780	15.78683508	1234	0.060360604	-0.602312441	normal	0.919174587	-0.276242632	normal	0.969974326	0.161277691	normal	0.611223041	-0.214581583	normal	[E]	Amino acid transport and metabolism	Molecular Function: glutamate-ammonia ligase activity (GO:0004356);; Biological Process: nitrogen compound metabolic process (GO:0006807);; 	--	--	[E]	Amino acid transport and metabolism	"Glutamine synthetase, catalytic domain;; Glutamine synthetase, beta-Grasp domain"	Lengsin GN=LGSN OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: lengsin-like [Tupaia chinensis]
ENSG00000146192(FGD2)	--	0.0162679	1	0	0	0	0	0.0162836	1	0.0158253	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Molecular Function: metal ion binding (GO:0046872);; 	"K05721|0|hsa:221472|FGD2, ZFYVE4; FYVE, RhoGEF and PH domain containing 2; K05721 FYVE, RhoGEF and PH domain containing 2 (A)"	--	[T]	Signal transduction mechanisms	RhoGEF domain;; FYVE zinc finger;; PH domain;; FYVE-type zinc finger	"FYVE, RhoGEF and PH domain-containing protein 2 GN=FGD2 OS=Homo sapiens (Human) PE=2 SV=1"	T	Signal transduction mechanisms	"PREDICTED: FYVE, RhoGEF and PH domain-containing protein 2 [Pteropus alecto]"
ENSG00000146197(SCUBE3)	--	0.069565228	10	0.152798212	22	0.073972297	10	0.090984164	13	0.121786007	17	0.09668756	14	--	--	--	0.984223952	-0.364794124	normal	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; GCC2 and GCC3;; EGF-like domain;; EGF domain;; CUB domain	"Signal peptide, CUB and EGF-like domain-containing protein 3 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: signal peptide, CUB domain, EGF-like 3 isoformX1 [Equus caballus]"
ENSG00000146205(ANO7)	--	0.870230956	85	0.831680274	83	0.804776236	81	0.426717283	42	0.466987309	44	0.270460295	27	0.114837248	-1.021098263	normal	0.277273169	-0.913783886	normal	0.000850474	-1.541020738	down	0.005748723	-1.162158854	down	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[S]	Function unknown	Calcium-activated chloride channel	Anoctamin-7 GN=ANO7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: anoctamin-7 [Eptesicus fuscus]
ENSG00000146215(CRIP3)	--	0.290465902	4	0.2186864	3	0.140588	1	0.235224207	1	0.673259809	8	0.2322236	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	Cysteine-rich protein 3 GN=CRIP3 OS=Homo sapiens (Human) PE=2 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: cysteine-rich protein 3 isoform X1 [Oryctolagus cuniculus]
ENSG00000146216(TTBK1)	--	0.055147898	4	0.0434772	7	0.087875395	5	0.054429483	6	0.035770479	3	0.035883355	4	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08815|0|hsa:84630|TTBK1, BDTK; tau tubulin kinase 1 (EC:2.7.11.1); K08815 tau tubulin kinase [EC:2.7.11.26] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Tau-tubulin kinase 1 GN=TTBK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tau-tubulin kinase 1 [Elephantulus edwardii]
ENSG00000146221(TCTE1)	--	0.0457679	3	0.0153339	1	0	0	0.0154628	1	0.0446401	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeat;; Leucine Rich repeats (2 copies)	T-complex-associated testis-expressed protein 1 GN=TCTE1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: T-complex-associated testis-expressed protein 1 [Ceratotherium simum simum]
ENSG00000146223(RPL7L1)	--	40.77164	2793	36.744038	2673	35.65788	2605	42.91024	3084	42.188666	3089	35.17218	2563	0.987211333	0.112096232	normal	0.979494457	0.187154911	normal	0.988862416	-0.031722769	normal	0.681932859	0.092463682	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L30p/L7e;; Ribosomal L30 N-terminal domain	60S ribosomal protein L7-like 1 GN=RPL7L1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L7-like 1 [Tupaia chinensis]
ENSG00000146232(NFKBIE)	--	3.61730919	184	4.223317673	210	4.908550821	252	4.605604	232	3.701696	177	4.939050404	234	0.910583973	0.301341871	normal	0.928121945	-0.265977295	normal	0.961510144	-0.114493433	normal	0.961743152	-0.027569703	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K05872|0|hsa:4794|NFKBIE, IKBE; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon; K05872 NF-kappa-B inhibitor epsilon (A)"	T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Neurotrophin signaling pathway (ko04722);; Adipocytokine signaling pathway (ko04920);; Epstein-Barr virus infection (ko05169)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	NF-kappa-B inhibitor epsilon GN=NFKBIE OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: NF-kappa-B inhibitor epsilon [Oryctolagus cuniculus]
ENSG00000146233(CYP39A1)	--	1.074117537	35	0.3948415	13	0.6647499	22	0.395088764	13	0.5529223	18	0.658288167	21	0.437006892	-1.358215059	normal	--	--	--	0.987985949	-0.070448547	normal	0.624077398	-0.44854513	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	K07439|0|pps:100994949|24-hydroxycholesterol 7-alpha-hydroxylase; K07439 24-hydroxycholesterol 7alpha-hydroxylase [EC:1.14.13.99] (A)	Primary bile acid biosynthesis (ko00120)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	24-hydroxycholesterol 7-alpha-hydroxylase GN=CYP39A1 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 24-hydroxycholesterol 7-alpha-hydroxylase isoform X7 [Canis lupus familiaris]
ENSG00000146242(TPBG)	--	69.02751413	3292	62.8928993	3042	61.67231988	3031	55.42948522	2707	50.58876522	2450	60.66907397	2923	0.93214353	-0.312940335	normal	0.911752549	-0.333479823	normal	0.989412726	-0.060604671	normal	0.179622649	-0.233991839	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat N-terminal domain;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeat C-terminal domain	Trophoblast glycoprotein (Precursor) GN=TPBG OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: trophoblast glycoprotein [Orycteropus afer afer]
ENSG00000146243(IRAK1BP1)	--	1.268324132	96	1.089834382	90	1.372453584	111	1.455524412	117	1.403760956	114	1.793832809	128	0.951638743	0.250927709	normal	0.935860964	0.314899684	normal	0.957739577	0.194819101	normal	0.595744909	0.252919985	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF541)	Interleukin-1 receptor-associated kinase 1-binding protein 1 GN=IRAK1BP1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: interleukin-1 receptor-associated kinase 1-binding protein 1 [Sus scrofa]
ENSG00000146247(PHIP)	--	8.502795239	1600	10.2241104	1923	9.633130705	1773	9.755741586	1848	9.072582031	1704	9.087953585	1701	0.973436638	0.176902428	normal	0.970507743	-0.195696373	normal	0.984203689	-0.06804158	normal	0.904901829	-0.033249434	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11797|0|hsa:55023|PHIP, BRWD2, DCAF14, WDR11, ndrp; pleckstrin homology domain interacting protein; K11797 PH-interacting protein (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Bromodomain"	PH-interacting protein GN=PHIP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: PH-interacting protein [Leptonychotes weddellii]
ENSG00000146250(PRSS35)	--	0.159523	7	0.0896553	4	0.0897634	3	0.0224945	1	0.110653	4	0.112979	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	--	--	Trypsin	Inactive serine protease 35 (Precursor) GN=PRSS35 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: inactive serine protease 35 [Trichechus manatus latirostris]
ENSG00000146263(MMS22L)	--	5.775255289	612	7.146400114	756	6.794841283	727	5.722119888	669	4.975405497	509	4.756720865	537	0.970040142	0.097408361	normal	0.111201859	-0.590697038	normal	0.580440689	-0.444245235	normal	0.12518289	-0.310646904	normal	--	--	--	--	--	--	--	"S-phase genomic integrity recombination mediator, N-terminal;; S-phase genomic integrity recombination mediator, C-terminal"	Protein MMS22-like GN=MMS22L OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: protein MMS22-like [Galeopterus variegatus]
ENSG00000146267(FAXC)	--	2.662100311	117	2.433549579	139	2.46000757	123	2.1808037	118	2.315806467	89	1.520393264	86	0.969485644	-0.018314456	normal	0.469411739	-0.655642985	normal	0.795951382	-0.516900062	normal	0.340667982	-0.393656898	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: protein targeting to mitochondrion (GO:0006626);; 	--	--	[T]	Signal transduction mechanisms	"Glutathione S-transferase, C-terminal domain"	Failed axon connections homolog GN=FAXC OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_010960 [Ailuropoda melanoleuca]
ENSG00000146278(PNRC1)	--	26.133629	767	30.58874391	886	23.54939772	688	21.51420769	627	27.26597256	796	43.68264348	1288	0.870617568	-0.320881022	normal	0.961366513	-0.175648334	normal	2.80E-05	0.894899865	normal	0.790312837	0.192310477	normal	--	--	--	"K18774|1.00626e-175|hsa:10957|PNRC1, B4-2, PNAS-145, PROL2, PRR2; proline-rich nuclear receptor coactivator 1; K18774 proline-rich nuclear receptor coactivator 1 (A)"	--	--	--	Proline-rich nuclear receptor coactivator	Proline-rich nuclear receptor coactivator 1 GN=PNRC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: proline-rich nuclear receptor coactivator 1 [Tupaia chinensis]
ENSG00000146281(PM20D2)	--	11.1407	722	15.6056	1018	15.8497	1019	18.9219	1247	15.8454	1027	18.1932	1186	0.001585033	0.756319755	normal	0.979320973	-0.008715048	normal	0.957138714	0.210368869	normal	0.190367607	0.305421018	normal	[R]	General function prediction only	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	--	--	Peptidase dimerisation domain;; Peptidase family M20/M25/M40	Peptidase M20 domain-containing protein 2 GN=PM20D2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: peptidase M20 domain-containing protein 2 [Tupaia chinensis]
ENSG00000146282(RARS2)	--	14.74212395	533	14.01433239	507	13.75203014	491	14.4584574	509	14.79763882	527	10.4804561	378	0.96773617	-0.097015917	normal	0.970882849	0.034290335	normal	0.775200849	-0.384275313	normal	0.618863599	-0.136728999	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: arginine-tRNA ligase activity (GO:0004814);; Molecular Function: ATP binding (GO:0005524);; Biological Process: arginyl-tRNA aminoacylation (GO:0006420);; 	"K01887|0|pps:100991764|RARS2; arginyl-tRNA synthetase 2, mitochondrial; K01887 arginyl-tRNA synthetase [EC:6.1.1.19] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	tRNA synthetases class I (R);; DALR anticodon binding domain	"Probable arginine--tRNA ligase, mitochondrial (Precursor) GN=RARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable arginine--tRNA ligase, mitochondrial [Tupaia chinensis]"
ENSG00000146350(TBC1D32)	--	1.207869833	91	1.6073148	114	1.794673366	121	1.519794258	105	1.5526983	114	1.007419232	79	0.964035799	0.172899421	normal	0.968263864	-0.021146046	normal	0.645397061	-0.613807961	normal	0.788563773	-0.151173635	normal	--	--	--	--	--	--	--	Broad-minded protein	Protein broad-minded GN=TBC1D32 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: protein broad-minded [Ursus maritimus]
ENSG00000146352(CLVS2)	--	0.562882253	66	0.37633113	53	0.337917343	29	0.179784354	30	0.7035523	62	0.387236877	25	0.144001556	-1.128376002	normal	0.97041845	0.199580004	normal	0.983928077	-0.210578679	normal	0.72414429	-0.361275402	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	"CRAL/TRIO domain;; Divergent CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain"	Clavesin-2 GN=CLVS2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: clavesin-2 [Galeopterus variegatus]
ENSG00000146373(RNF217)	--	10.55523266	741	9.958479659	813	8.867163258	666	8.636619517	753	9.22760184	802	11.36263633	836	0.976121541	-0.007640227	normal	0.975864993	-0.041002881	normal	0.87470271	0.319041399	normal	0.743840289	0.085903902	normal	--	--	--	"K11977|0|hsa:154214|RNF217, C6orf172, IBRDC1, dJ84N20.1; ring finger protein 217; K11977 E3 ubiquitin-protein ligase RNF217 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain	Probable E3 ubiquitin-protein ligase RNF217 GN=RNF217 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase RNF217 [Lipotes vexillifer]
ENSG00000146374(RSPO3)	--	30.42074262	1628	34.35271759	1860	32.14252864	1687	23.170534	1271	36.087625	1912	35.59468943	1895	0.770458843	-0.38755375	normal	0.985885373	0.018338638	normal	0.976894599	0.159311617	normal	0.909622586	-0.047347761	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thrombospondin type 1 domain	R-spondin-3 (Precursor) GN=RSPO3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: R-spondin-3 [Galeopterus variegatus]
ENSG00000146376(ARHGAP18)	--	9.566641905	730	9.654251754	730	9.74814388	731	9.56226793	736	10.12384931	772	10.78531021	812	0.975778848	-0.018983171	normal	0.974210096	0.059158646	normal	0.966822656	0.143036	normal	0.830751125	0.061652169	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain	Rho GTPase-activating protein 18 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 18 isoform X1 [Galeopterus variegatus]
ENSG00000146386(ABRACL)	--	36.7391463	366	39.42454693	391	46.02472703	457	52.37017201	530	41.39866267	412	62.028227	621	0.410888203	0.501557999	normal	0.967630949	0.053846279	normal	0.632121142	0.43287422	normal	0.261670904	0.344076475	normal	--	--	--	--	--	[S]	Function unknown	Costars	Costars family protein ABRACL GN=ABRACL OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: costars family protein ABRACL [Equus przewalskii]
ENSG00000146409(SLC18B1)	--	7.283732606	228	5.3989077	176	4.966352173	154	8.893617456	282	8.977628	280	9.443014165	295	0.91894011	0.274165371	normal	0.179387141	0.644001258	normal	0.001433184	0.922833328	normal	0.016291317	0.597566648	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Major Facilitator Superfamily;; LacY proton/sugar symporter	MFS-type transporter SLC18B1 GN=SLC18B1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: MFS-type transporter SLC18B1 [Galeopterus variegatus]
ENSG00000146410(MTFR2)	--	9.487192369	240	9.076989861	237	7.798928293	203	6.106011775	163	5.460187507	133	6.118245504	160	0.375724491	-0.584423867	normal	0.014149685	-0.847563803	normal	0.886626973	-0.348765566	normal	0.0318767	-0.598116604	normal	--	--	--	--	--	--	--	Mitochondrial fission regulator	Mitochondrial fission regulator 2 GN=MTFR2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mitochondrial fission regulator 2 [Pteropus alecto]
ENSG00000146411(SLC2A12)	--	1.91287	138	1.46703	105	1.31171	92	1.17781	85	1.66044	119	1.14534	83	0.314521874	-0.719650829	normal	0.961663836	0.157020363	normal	0.967168358	-0.154145044	normal	0.621639164	-0.244587419	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08149|0|hsa:154091|SLC2A12, GLUT12, GLUT8; solute carrier family 2 (facilitated glucose transporter), member 12; K08149 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 12 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 12 GN=SLC2A12 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 12 [Tupaia chinensis] "
ENSG00000146414(SHPRH)	--	2.670950451	356	3.156221119	417	3.02507951	397	2.795619546	374	2.9317206	352	2.688055093	355	0.968273482	0.040159665	normal	0.917984234	-0.264851634	normal	0.954078417	-0.168930531	normal	0.656178816	-0.135489613	normal	[KL]	"Transcription;; Replication, recombination and repair"	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K15710|0|hsa:257218|SHPRH, bA545I5.2; SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase; K15710 E3 ubiquitin-protein ligase SHPRH [EC:3.6.4.- 6.3.2.19] (A)"	--	[L]	"Replication, recombination and repair"	"SNF2 family N-terminal domain;; linker histone H1 and H5 family;; Zinc finger, C3HC4 type (RING finger);; Helicase conserved C-terminal domain"	E3 ubiquitin-protein ligase SHPRH GN=SHPRH OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_011861 [Ailuropoda melanoleuca]
ENSG00000146416(AIG1)	--	25.96486106	423	31.79142762	518	27.99741713	379	30.61955147	499	28.1156174	428	39.29293003	585	0.944868019	0.20685754	normal	0.895892829	-0.295816118	normal	0.084139284	0.615954014	normal	0.601492541	0.174726974	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[W]	Extracellular structures	FAR-17a/AIG1-like protein	Androgen-induced gene 1 protein GN=AIG1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: androgen-induced gene 1 protein isoform X2 [Lipotes vexillifer]
ENSG00000146425(DYNLT1)	--	60.710966	612	56.79245264	575	60.04981354	599	71.971593	742	70.76299467	705	64.838046	663	0.932382411	0.246492597	normal	0.916562162	0.271987769	normal	0.964952141	0.137830543	normal	0.307401819	0.219014453	normal	--	--	--	"K10420|1.08588e-78|ptr:463098|DYNLT1; dynein, light chain, Tctex-type 1; K10420 dynein light chain Tctex-type 1 (A)"	--	[N]	Cell motility	Tctex-1 family	Dynein light chain Tctex-type 1 GN=DYNLT1 OS=Homo sapiens (Human) PE=1 SV=1	N	Cell motility	PREDICTED: dynein light chain Tctex-type 1 [Orcinus orca]
ENSG00000146426(TIAM2)	--	11.55649272	1163	14.07512776	1197	11.75624229	1112	10.81852734	1050	11.57317144	1182	11.12118507	1163	0.965715375	-0.178046332	normal	0.980566046	-0.039569366	normal	0.979948001	0.056327956	normal	0.841675955	-0.053312986	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K16847|0|pps:100974804|TIAM2; T-cell lymphoma invasion and metastasis 2; K16847 T-lymphoma invasion and metastasis-inducing protein 2 (A)	--	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; Pleckstrin homology domain;; PDZ domain (Also known as DHR or GLGF)	T-lymphoma invasion and metastasis-inducing protein 2 GN=TIAM2 OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: T-lymphoma invasion and metastasis-inducing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000146433(TMEM181)	--	17.30526	1468	17.41971774	1478	19.60740074	1625	19.176064	1643	17.506851	1486	19.4297	1652	0.978320029	0.131518095	normal	0.983474578	-0.013624808	normal	0.984908491	0.015468249	normal	0.873568706	0.043762001	normal	--	--	--	--	--	--	--	Wnt-binding factor required for Wnt secretion	Transmembrane protein 181 GN=TMEM181 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 181 [Odobenus rosmarus divergens]
ENSG00000146453(PNLDC1)	--	0.060635879	2	0.030346912	1	0.060065736	1	0	0	0.029478499	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CAF1 family ribonuclease	Poly(A)-specific ribonuclease PARN-like domain-containing protein 1 (Precursor) GN=PNLDC1 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: poly(A)-specific ribonuclease PARN-like domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000146457(WTAP)	--	31.219395	1088	28.67788	1008	29.27023	1018	38.50254	1324	41.827652	1426	44.27453	1511	0.941785543	0.252069218	normal	0.44756143	0.478445532	normal	0.130000975	0.560786551	normal	0.005132373	0.431608202	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: mRNA methylation (GO:0080009);; 	--	--	[A]	RNA processing and modification	--	Pre-mRNA-splicing regulator WTAP GN=WTAP OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: pre-mRNA-splicing regulator WTAP isoform X1 [Tupaia chinensis]
ENSG00000146463(ZMYM4)	--	10.23576146	1387	14.11770358	1630	11.09083327	1514	9.793834682	1371	11.03269375	1522	11.83020556	1643	0.982424607	-0.047518535	normal	0.97932145	-0.12021471	normal	0.980628386	0.109570746	normal	0.951818551	-0.019066169	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	Domain of unknown function (DUF3504);; MYM-type Zinc finger with FCS sequence motif	Zinc finger MYM-type protein 4 GN=ZMYM4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger MYM-type protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000146469(VIP)	--	0	0	0	0	0	0	0.128520871	3	0.04190639	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05264|4.86713e-107|pps:100978990|VIP; vasoactive intestinal peptide; K05264 vasoactive intestinal peptide (A)	--	--	--	Peptide hormone	Vasoactive intestinal peptide (Precursor) GN=VIP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: VIP peptides [Galeopterus variegatus]
ENSG00000146476(ARMT1)	--	14.11371358	510	14.838209	538	14.84421306	527	16.80621376	615	16.08451936	580	14.14821592	511	0.933881251	0.238601589	normal	0.96880004	0.086785191	normal	0.970989657	-0.052617766	normal	0.742874168	0.093536251	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function DUF89	UPF0364 protein C6orf211 GN=C6orf211 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0364 protein C6orf211 homolog [Canis lupus familiaris]
ENSG00000146477(SLC22A3)	--	13.0293	688	15.1508	808	12.0591	637	54.1148	2882	61.4489	3232	45.7845	2421	0	2.033350791	up	0	1.976575671	up	0	1.915438658	up	5.77E-21	1.978614223	up	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08200|0|hsa:6581|SLC22A3, EMT, EMTH, OCT3; solute carrier family 22 (organic cation transporter), member 3; K08200 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 3 (A)"	Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Major Facilitator Superfamily;; Sugar (and other) transporter	Solute carrier family 22 member 3 GN=SLC22A3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 22 member 3 [Sus scrofa]
ENSG00000146530(VWDE)	--	0.778748743	86	0.678651153	73	1.02876031	96	1.611852861	177	0.987644578	99	1.0100593	105	0.004866983	0.997833614	normal	0.911882209	0.410773675	normal	0.967452801	0.119195657	normal	0.281979647	0.556590618	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	EGF-like domain;; Human growth factor-like EGF;; EGF-like domain;; von Willebrand factor type D domain	von Willebrand factor D and EGF domain-containing protein (Precursor) GN=VWDE OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: von Willebrand factor D and EGF domain-containing protein [Galeopterus variegatus]
ENSG00000146535(GNA12)	--	30.36032362	2303	29.29751733	2240	30.27875211	2318	32.24242482	2442	31.76331393	2408	28.83392324	2193	0.987694631	0.053681745	normal	0.986168369	0.082856144	normal	0.985951514	-0.088207023	normal	0.95908328	0.016323893	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	K04346|0|ptr:463234|GNA12; guanine nucleotide binding protein (G protein) alpha 12; K04346 guanine nucleotide-binding protein subunit alpha-12 (A)	MAPK signaling pathway (ko04010);; cGMP-PKG signaling pathway (ko04022);; Sphingolipid signaling pathway (ko04071);; Vascular smooth muscle contraction (ko04270);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200)	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	G-protein alpha subunit;; ADP-ribosylation factor family	Guanine nucleotide-binding protein subunit alpha-12 GN=GNA12 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit alpha-12 [Orcinus orca]
ENSG00000146540(C7orf50)	--	67.90603117	1372	59.21737209	1332	61.49293909	1354	77.703552	1698	71.806682	1489	66.69349737	1449	0.934382967	0.276445019	normal	0.975764091	0.139173611	normal	0.980656403	0.089441831	normal	0.378745526	0.170416339	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2373)	Uncharacterized protein C7orf50 GN=C7orf50 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C7orf50 homolog [Tupaia chinensis]
ENSG00000146555(SDK1)	--	1.52955734	297	1.129421963	222	2.0017441	270	2.95311396	428	2.6559828	534	2.657181302	516	0.48233756	0.494175648	normal	2.68E-08	1.239241706	up	0.000148769	0.922319389	normal	3.69E-06	0.885104086	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K16353|0|ggo:101152284|SDK1; protein sidekick-1; K16353 protein sidekick (A)	--	[T]	Signal transduction mechanisms	"Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Interferon-alpha/beta receptor, fibronectin type III;; CD80-like C2-set immunoglobulin domain;; zinc-finger binding domain of transposase IS66"	Protein sidekick-1 (Precursor) GN=SDK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein sidekick-1-like isoform X2 [Tupaia chinensis]
ENSG00000146574(CCZ1B)	--	5.294363	213	4.565785	183	4.192653	167	6.2800776	250	5.517548	218	4.883319	195	0.947563245	0.198916967	normal	0.939876446	0.229319855	normal	0.947102257	0.213543397	normal	0.550076256	0.21365657	normal	--	--	--	--	--	[V]	Defense mechanisms	Fungal domain of unknown function (DUF1712)	Vacuolar fusion protein CCZ1 homolog GN=CCZ1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: vacuolar fusion protein CCZ1 homolog B-like [Chrysochloris asiatica]
ENSG00000146576(C7orf26)	--	10.48106634	370	11.2259337	396	12.68557302	459	14.47228409	510	16.38896304	581	14.18583101	504	0.658374529	0.430611048	normal	0.309933959	0.529931035	normal	0.96359955	0.126241083	normal	0.085538454	0.359944653	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4507)	Uncharacterized protein C7orf26 GN=C7orf26 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C7orf26 homolog [Tupaia chinensis] 
ENSG00000146587(RBAK)	--	8.057644076	949	8.2422642	984	8.223254001	932	8.87069108	1033	9.173478778	1049	8.74882	1007	0.976110154	0.091386167	normal	0.977373929	0.070752576	normal	0.974911746	0.103209235	normal	0.723148269	0.087284683	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:57786|RBAK, ZNF769; RB-associated KRAB zinc finger; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	RB-associated KRAB zinc finger protein GN=RBAK OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: RB-associated KRAB zinc finger protein [Galeopterus variegatus] 
ENSG00000146592(CREB5)	--	0.698801823	69	0.652978166	61	0.705229184	68	0.552360971	69	0.431235247	58	0.481932794	21	0.975038566	-0.030160677	normal	0.974368011	-0.091847377	normal	0.001509654	-1.634478097	down	0.46713442	-0.44382563	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09047|4.54003e-173|cjc:100392579|CREB5; cAMP responsive element binding protein 5; K09047 cyclic AMP-responsive element-binding protein 5 (A)	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Thyroid hormone synthesis (ko04918);; Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Cyclic AMP-responsive element-binding protein 5 GN=CREB5 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: cyclic AMP-responsive element-binding protein 5 isoform 1 [Orcinus orca]
ENSG00000146648(EGFR)	--	48.81365494	8760	45.0057314	8147	49.37915068	8758	55.56059405	10553	46.72498598	8459	57.9627314	10541	0.987342285	0.237780108	normal	0.995366518	0.032785683	normal	0.984108	0.259006121	normal	0.382514045	0.182287282	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);; Cellular Component: membrane (GO:0016020);; 	"K04361|0|hsa:1956|EGFR, ERBB, ERBB1, HER1, NISBD2, PIG61, mENA; epidermal growth factor receptor (EC:2.7.10.1); K04361 epidermal growth factor receptor [EC:2.7.10.1] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Dorso-ventral axis formation (ko04320);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Oxytocin signaling pathway (ko04921);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Hepatitis C (ko05160);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Bladder cancer (ko05219);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Receptor L domain;; Growth factor receptor domain IV;; Protein kinase domain;; Furin-like cysteine rich region	Epidermal growth factor receptor (Precursor) GN=EGFR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor receptor isoform X1 [Loxodonta africana]
ENSG00000146670(CDCA5)	--	31.862619	1457	33.401776	1543	36.2151889	1664	33.487971	1531	29.012174	1316	31.788775	1466	0.983489513	0.040599376	normal	0.94746249	-0.250738703	normal	0.969079039	-0.19087682	normal	0.520594041	-0.134084797	normal	--	--	--	"K17390|1.80605e-130|hsa:113130|CDCA5, SORORIN; cell division cycle associated 5; K17390 sororin (A)"	MicroRNAs in cancer (ko05206)	--	--	Sororin protein	Sororin GN=CDCA5 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: sororin-like [Pteropus alecto] 
ENSG00000146674(IGFBP3)	--	124.1155337	4721	75.78222016	2930	81.5821721	3126	159.9664399	5917	128.6682916	4787	109.0237592	4080	0.962630824	0.294855287	normal	0.010247769	0.686514752	normal	0.864547799	0.375800347	normal	0.256839739	0.433491822	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	K10138|2.65601e-177|mcf:102144139|IGFBP3; insulin-like growth factor binding protein 3; K10138 insulin-like growth factor-binding protein 3 (A)	p53 signaling pathway (ko04115);; Transcriptional misregulation in cancer (ko05202)	--	--	Thyroglobulin type-1 repeat;; Insulin-like growth factor binding protein	Insulin-like growth factor-binding protein 3 (Precursor) GN=IGFBP3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: insulin-like growth factor-binding protein 3, partial [Bubalus bubalis]"
ENSG00000146676(PURB)	--	9.75027	1367	9.30075	1308	9.21856	1274	13.139	1858	12.1664	1706	11.4935	1615	0.707179675	0.41150694	normal	0.839136943	0.361461665	normal	0.876730712	0.333525028	normal	0.018096298	0.369485742	normal	--	--	--	--	--	[K]	Transcription	PurA ssDNA and RNA-binding protein;; Protein of unknown function (DUF3276)	Transcriptional activator protein Pur-beta GN=PURB OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: transcriptional activator protein Pur-beta [Oryctolagus cuniculus]
ENSG00000146678(IGFBP1)	--	10.80416206	242	6.098083911	134	8.4174166	190	31.4216826	715	19.3759489	436	45.96814527	1036	6.89E-14	1.526200315	up	1.99E-13	1.669629876	up	0	2.42936689	up	0.006860043	1.930078824	up	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Thyroglobulin type-1 repeat;; Insulin-like growth factor binding protein	Insulin-like growth factor-binding protein 1 (Precursor) GN=IGFBP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: insulin-like growth factor-binding protein 1 [Tupaia chinensis]
ENSG00000146700(SSC4D)	--	0.31681	16	0.268486	14	0.206671	10	0.0784022	4	0.115546	5	0.273379	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	"Scavenger receptor cysteine-rich domain-containing group B protein {ECO:0000303|PubMed:12466895, ECO:0000312|HGNC:HGNC:14461} (Precursor) OS=Homo sapiens (Human) PE=2 SV=1"	R	General function prediction only	PREDICTED: scavenger receptor cysteine-rich domain-containing group B protein [Condylura cristata]
ENSG00000146701(MDH2)	--	134.7827911	4235	132.4491979	4143	148.5774231	4743	152.4616789	5035	145.939189	4812	140.4501134	4583	0.981304898	0.218724702	normal	0.984230524	0.19446835	normal	0.992539226	-0.057780282	normal	0.598083532	0.115953323	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00026|0|ptr:463484|MDH2; malate dehydrogenase 2, NAD (mitochondrial); K00026 malate dehydrogenase [EC:1.1.1.37] (A)"	Citrate cycle (TCA cycle) (ko00020);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Glyoxylate and dicarboxylate metabolism (ko00630);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	"lactate/malate dehydrogenase, alpha/beta C-terminal domain;; lactate/malate dehydrogenase, NAD binding domain;; Semialdehyde dehydrogenase, NAD binding domain"	"Malate dehydrogenase, mitochondrial (Precursor) GN=MDH2 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: malate dehydrogenase, mitochondrial [Condylura cristata]"
ENSG00000146707(POMZP3)	--	11.37788579	288	10.71816674	270	8.725654409	224	10.43658499	262	9.982618849	253	13.56796814	351	0.953796764	-0.166403033	normal	0.960394573	-0.114585411	normal	0.127258052	0.636221644	normal	0.740304548	0.126500355	normal	--	--	--	--	--	--	--	Putative binding domain;; Zona pellucida-like domain	POM121 and ZP3 fusion protein GN=POMZP3 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: zona pellucida sperm-binding protein 3 [Vicugna pacos]
ENSG00000146729(GBAS)	--	51.09903528	1577	52.13805398	1597	46.99923962	1428	47.87064137	1486	52.94862403	1638	43.40391558	1359	0.979628048	-0.116463889	normal	0.984379034	0.015130339	normal	0.981186816	-0.079655483	normal	0.817686114	-0.059357192	normal	--	--	--	--	--	[S]	Function unknown	NIPSNAP	Protein NipSnap homolog 2 GN=GBAS OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein NipSnap homolog 2 [Camelus dromedarius]
ENSG00000146733(PSPH)	--	21.2576395	652	26.25934784	826	26.83091231	870	22.20426398	691	18.54253184	598	34.62155777	1192	0.973716545	0.05286048	normal	0.425643537	-0.486371365	normal	0.562388769	0.445341513	normal	0.949356766	0.060201049	normal	[E]	Amino acid transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: 5'-nucleotidase activity (GO:0008253);; 	K01079|7.4435e-165|pon:100189699|PSPH; DKFZP468A2313 protein (EC:3.1.3.3); K01079 phosphoserine phosphatase [EC:3.1.3.3] (A)	"Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Haloacid dehalogenase-like hydrolase;; Pyrimidine 5'-nucleotidase (UMPH-1);; Putative Phosphatase	Phosphoserine phosphatase GN=PSPH OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: phosphoserine phosphatase [Myotis brandtii] 
ENSG00000146755(TRIM50)	--	0.0262549	1	0	0	0	0	0	0	0.06619224	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12024|0|hsa:135892|TRIM50, TRIM50A; tripartite motif containing 50; K12024 tripartite motif-containing protein 50/73/74 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; RING-type zinc-finger;; Ring finger domain"	E3 ubiquitin-protein ligase TRIM50 GN=TRIM50 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM50 isoform X1 [Vicugna pacos]
ENSG00000146757(ZNF92)	--	5.169318555	281	4.62701686	248	4.38114247	234	5.998278188	332	4.788455708	262	4.682563	253	0.943242606	0.208729991	normal	0.964782151	0.057459227	normal	0.962585884	0.103692789	normal	0.717190396	0.128397954	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; Zinc-finger double-stranded RNA-binding;; C1-like domain;; Desulfoferrodoxin, N-terminal domain;; Domain of unknown function (DUF1610)"	Zinc finger protein 92 GN=ZNF92 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000146776(ATXN7L1)	--	5.449171767	195	4.640382963	251	2.690647433	209	3.801587748	144	4.295959315	158	2.510778452	159	0.755257924	-0.463965305	normal	0.131051032	-0.683946854	normal	0.836681794	-0.399443301	normal	0.068545944	-0.527762023	normal	--	--	--	"K11318|0|hsa:222255|ATXN7L1, ATXN7L4; ataxin 7-like 1; K11318 ataxin-7 (A)"	--	[B]	Chromatin structure and dynamics	"SCA7, zinc-binding domain"	Ataxin-7-like protein 1 GN=ATXN7L1 OS=Homo sapiens (Human) PE=2 SV=3	B	Chromatin structure and dynamics	PREDICTED: ataxin-7-like protein 1 isoform X2 [Camelus dromedarius]
ENSG00000146802(TMEM168)	--	7.834818013	491	6.923197769	478	7.000957255	462	5.869572087	379	6.423137155	366	5.851226156	358	0.732466784	-0.402917751	normal	0.736050253	-0.405123984	normal	0.796757733	-0.37482698	normal	0.062038964	-0.397032061	normal	--	--	--	--	--	--	--	--	Transmembrane protein 168 GN=TMEM168 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 168 [Tupaia chinensis] 
ENSG00000146826(C7orf43)	--	6.226500269	260	5.544072658	233	4.698892407	204	6.357024608	278	9.480271449	385	6.330903537	267	0.965549924	0.065367409	normal	0.044158008	0.699535202	normal	0.836468519	0.377525867	normal	0.211018046	0.39465674	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C7orf43 GN=C7orf43 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C7orf43 homolog [Dasypus novemcinctus]
ENSG00000146828(SLC12A9)	--	12.47118127	532	9.562000878	452	15.68371602	620	12.75848774	589	12.60242035	615	9.863264387	454	0.966468977	0.115691506	normal	0.677079564	0.421623452	normal	0.550610442	-0.456560533	normal	0.956289101	0.026382884	normal	[E]	Amino acid transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14429|0|pps:100979915|SLC12A9; solute carrier family 12, member 9; K14429 solute carrier family 12 (potassium/chloride transporters), member 9 (A)"	--	[E]	Amino acid transport and metabolism	Amino acid permease	Solute carrier family 12 member 9 GN=SLC12A9 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 12 member 9 [Ceratotherium simum simum]
ENSG00000146830(GIGYF1)	--	11.007786	1465	11.40011358	1558	10.239159	1393	8.80445383	1158	9.552362	1246	13.041348	1735	0.807836461	-0.369660435	normal	0.86509556	-0.343444076	normal	0.909771176	0.308148637	normal	0.75833601	-0.113594771	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K18730|0|hsa:64599|GIGYF1, GYF1, PERQ1; GRB10 interacting GYF protein 1; K18730 PERQ amino acid-rich with GYF domain-containing protein (A)"	--	[R]	General function prediction only	GYF domain	PERQ amino acid-rich with GYF domain-containing protein 1 GN=GIGYF1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: PERQ amino acid-rich with GYF domain-containing protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000146833(TRIM4)	--	14.73889391	830	15.8597222	902	14.26836489	800	15.45768273	871	15.54719223	852	16.4912537	934	0.977063972	0.03865926	normal	0.97301783	-0.103521943	normal	0.951004811	0.214755046	normal	0.868332882	0.048367369	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K11998|0|hsa:89122|TRIM4, RNF87; tripartite motif containing 4; K11998 tripartite motif-containing protein 4 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; RING-type zinc-finger;; SPRY-associated domain;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	E3 ubiquitin-protein ligase TRIM4 GN=TRIM4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 4 isoform X2 [Equus przewalskii]
ENSG00000146834(MEPCE)	--	21.644441	1270	21.8874754	1300	20.020129	1176	19.83386044	1145	17.27613822	980	21.13552	1219	0.966783704	-0.180083572	normal	0.644769309	-0.428508301	normal	0.981004643	0.043463724	normal	0.341922798	-0.185009224	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	K15190|0|pps:100987184|MEPCE; methylphosphate capping enzyme; K15190 7SK snRNA methylphosphate capping enzyme [EC:2.1.1.-] (A)	--	[R]	General function prediction only	Bicoid-interacting protein 3 (Bin3);; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain	7SK snRNA methylphosphate capping enzyme GN=MEPCE OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: 7SK snRNA methylphosphate capping enzyme [Leptonychotes weddellii]
ENSG00000146842(TMEM209)	--	14.30549762	725	14.54066236	732	13.52673055	667	13.88152356	712	13.70210196	700	13.54334346	701	0.974334238	-0.056814516	normal	0.971910802	-0.085734135	normal	0.973507518	0.063296242	normal	0.932648816	-0.028885402	normal	--	--	--	--	--	[S]	Function unknown	"Cytochrome B561, N terminal"	Transmembrane protein 209 GN=TMEM209 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 209 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000146856(AGBL3)	--	1.60082775	46	1.694934925	43	1.740368237	42	1.942876452	41	1.40679713	36	1.653547908	42	0.97765002	-0.190111617	normal	0.974351827	-0.267471096	normal	0.980929166	-0.00800327	normal	0.854372158	-0.159869822	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[E]	Amino acid transport and metabolism	Zinc carboxypeptidase	Cytosolic carboxypeptidase 3 GN=AGBL3 OS=Homo sapiens (Human) PE=2 SV=2	E	Amino acid transport and metabolism	PREDICTED: cytosolic carboxypeptidase 3 [Odobenus rosmarus divergens]
ENSG00000146858(ZC3HAV1L)	--	11.93352902	933	14.55325748	1140	11.20975756	866	9.703824	730	10.96616887	854	11.42426673	895	0.758537252	-0.384095712	normal	0.608623851	-0.437479335	normal	0.97754629	0.039161942	normal	0.250809028	-0.266472448	normal	--	--	--	--	--	--	--	--	Zinc finger CCCH-type antiviral protein 1-like GN=ZC3HAV1L OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger CCCH-type antiviral protein 1-like [Tursiops truncatus]
ENSG00000146859(TMEM140)	--	12.002	428	13.7888	492	12.4866	446	12.7796	454	12.3845	438	14.7958	528	0.969212886	0.054060803	normal	0.949983756	-0.188539372	normal	0.934758272	0.234471275	normal	0.925960777	0.035086259	normal	--	--	--	--	--	--	--	TM140 protein family	Transmembrane protein 140 GN=TMEM140 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 140 [Galeopterus variegatus]
ENSG00000146872(TLK2)	--	14.53229488	997	14.13987352	976	14.73550258	980	15.84551656	1132	16.67146751	1203	14.74272798	1042	0.969989045	0.152156133	normal	0.922878931	0.279865834	normal	0.977261396	0.080090308	normal	0.394152521	0.172175892	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08864|0|hsa:11011|TLK2, HsHPK, PKU-ALPHA; tousled-like kinase 2 (EC:2.7.11.1); K08864 tousled-like kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase tousled-like 2 GN=TLK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_011027 [Ailuropoda melanoleuca]
ENSG00000146904(EPHA1)	--	0	0	0	0	0	0	0	0	0	0	0.0145042	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05102|0|hsa:2041|EPHA1, EPH, EPHT, EPHT1; EPH receptor A1 (EC:2.7.10.1); K05102 Eph receptor A1 [EC:2.7.10.1] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Ephrin type-A receptor 2 transmembrane domain	Ephrin type-A receptor 1 (Precursor) GN=EPHA1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 1 isoform X1 [Mustela putorius furo] 
ENSG00000146909(NOM1)	--	5.338536294	678	4.947187358	636	5.195729609	663	6.64719	849	6.977123848	883	5.896519565	751	0.90187248	0.293052553	normal	0.561127761	0.451046206	normal	0.960174889	0.171145587	normal	0.099555523	0.307304579	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	"K17583|0|hsa:64434|NOM1, C7orf3, PPP1R113, SGD1; nucleolar protein with MIF4G domain 1; K17583 nucleolar MIF4G domain-containing protein 1 (A)"	--	[T]	Signal transduction mechanisms	MA3 domain;; MIF4G domain	Nucleolar MIF4G domain-containing protein 1 GN=NOM1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: nucleolar MIF4G domain-containing protein 1, partial [Orycteropus afer afer]"
ENSG00000146910(CNPY1)	--	0	0	0	0	0	0	0	0	0	0	0.085220912	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	TLR4 regulator and MIR-interacting MSAP	Protein canopy homolog 1 GN=CNPY1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein canopy homolog 1 [Camelus bactrianus]
ENSG00000146918(NCAPG2)	--	31.358905	2248	28.89945	2070	33.75442349	2378	28.31698054	2043	24.84004878	1751	25.06577688	1773	0.978166008	-0.168664108	normal	0.949681018	-0.26266931	normal	0.657150839	-0.431528614	normal	0.080025982	-0.287878439	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K11492|0|hsa:54892|NCAPG2, CAP-G2, CAPG2, LUZP5, MTB, hCAP-G2; non-SMC condensin II complex, subunit G2; K11492 condensin-2 complex subunit G2 (A)"	--	[S]	Function unknown	Condensin II non structural maintenance of chromosomes subunit;; HEAT repeat	Condensin-2 complex subunit G2 GN=NCAPG2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: condensin-2 complex subunit G2 isoform X1 [Equus caballus] 
ENSG00000146938(NLGN4X)	--	0.009595172	1	0.009683579	1	0	0	0.009082556	1	0	0	0.030599815	2	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K07378|0|mcf:102145911|NLGN4X; neuroligin 4, X-linked; K07378 neuroligin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	"Neuroligin-4, X-linked (Precursor) GN=NLGN4X OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: neuroligin-4, X-linked [Equus caballus]"
ENSG00000146950(SHROOM2)	--	0.581996174	95	0.49786721	73	0.470454499	77	0.54530521	80	0.604935709	99	0.332091706	55	0.953567501	-0.273924973	normal	0.911882209	0.410773675	normal	0.909695945	-0.482454514	normal	0.903212386	-0.088333191	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: actin filament binding (GO:0051015);; 	"K18625|0|hsa:357|SHROOM2, APXL, HSAPXL; shroom family member 2; K18625 protein Shroom (A)"	Tight junction (ko04530)	--	--	Apx/Shroom domain ASD2;; Apx/Shroom domain ASD1;; PDZ domain (Also known as DHR or GLGF)	Protein Shroom2 GN=SHROOM2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: protein Shroom2 isoform X3 [Canis lupus familiaris]
ENSG00000146955(RAB19)	--	0	0	0.217621	2	0	0	0.0848252	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K17047|3.41893e-162|ptr:463777|RAB19; RAB19, member RAS oncogene family; K17047 Ras-related protein Rab-19 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-19 GN=RAB19 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-19 isoform X1 [Myotis brandtii] 
ENSG00000146963(LUC7L2)	--	43.3874927	1707	49.49552188	2048	48.51698879	1937	41.8880532	1691	42.978655	1875	44.36611863	1893	0.984747817	-0.044378529	normal	0.979269296	-0.148636921	normal	0.986027651	-0.041408281	normal	0.726846246	-0.081103286	normal	[A]	RNA processing and modification	Molecular Function: mRNA binding (GO:0003729);; Cellular Component: U1 snRNP (GO:0005685);; Biological Process: mRNA splice site selection (GO:0006376);; 	K13212|3.3271e-156|shr:100928142|LUC7L2; LUC7-like 2 (S. cerevisiae); K13212 RNA-binding protein Luc7-like 2 (A)	--	[A]	RNA processing and modification	LUC7 N_terminus	Putative RNA-binding protein Luc7-like 2 GN=LUC7L2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: putative RNA-binding protein Luc7-like 2 isoform 1 [Sarcophilus harrisii]
ENSG00000146966(DENND2A)	--	0.938797273	53	1.001755947	47	0.900531921	60	0.849810085	49	0.918406607	65	0.389838791	31	0.976811841	-0.139825687	normal	0.939239458	0.434421665	normal	0.538640205	-0.927886233	normal	0.835100739	-0.163725123	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; uDENN domain;; dDENN domain	DENN domain-containing protein 2A GN=DENND2A OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 2A [Ceratotherium simum simum]
ENSG00000147003(TMEM27)	--	0.252332	6	0.127855	3	0.169867	3	1.51018	36	0.82121	19	1.20843	29	0.004838353	2.289275462	up	--	--	--	0.003504749	2.750763264	up	--	--	--	--	--	--	--	--	--	--	--	Collectrin (Precursor) GN=TMEM27 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: collectrin [Ursus maritimus]
ENSG00000147010(SH3KBP1)	--	33.96648102	2588	29.33219448	2237	30.15737284	2287	42.99485481	3209	40.05249565	3016	29.34221433	2277	0.95269192	0.27930477	normal	0.769719289	0.409405457	normal	0.988005901	-0.014603838	normal	0.348758594	0.235341477	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12470|0|ggo:101130648|SH3KBP1; SH3 domain-containing kinase-binding protein 1 isoform 1; K12470 SH3 domain-containing kinase-binding protein 1 (A)	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Variant SH3 domain;; SH3 domain;; Variant SH3 domain	SH3 domain-containing kinase-binding protein 1 GN=SH3KBP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SH3 domain-containing kinase-binding protein 1 isoform 1 [Orcinus orca]
ENSG00000147027(TMEM47)	--	5.24748	279	5.55764	296	4.15426	217	9.84609	530	8.26424	441	8.96054	480	0.00030019	0.891277052	normal	0.294708047	0.551432768	normal	7.99E-07	1.131608472	up	9.46E-06	0.851417497	normal	--	--	--	--	--	[R]	General function prediction only	PMP-22/EMP/MP20/Claudin tight junction	Transmembrane protein 47 GN=TMEM47 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 47 [Sorex araneus]
ENSG00000147036(LANCL3)	--	0	0	0	0	0.013463203	1	0.044220016	3	0.0631591	2	0.00660713	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Lanthionine synthetase C-like protein	LanC-like protein 3 GN=LANCL3 OS=Homo sapiens (Human) PE=2 SV=2	V	Defense mechanisms	PREDICTED: lanC-like protein 3 [Ochotona princeps]
ENSG00000147041(SYTL5)	--	0	0	0.021394021	2	0	0	0.234875	22	0.520095	49	0.223048	21	0.001475622	3.922870012	up	1.70E-08	3.829664793	up	0.00217057	3.892046042	up	0.000105635	5.499413741	up	--	--	--	"K17598|0|hsa:94122|SYTL5, slp5; synaptotagmin-like 5; K17598 synaptotagmin-like protein (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; FYVE-type zinc finger	Synaptotagmin-like protein 5 GN=SYTL5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-like protein 5 [Tupaia chinensis]
ENSG00000147044(CASK)	--	24.9036322	1460	26.78695256	1551	28.15643101	1479	34.17680747	2130	30.7686977	1890	34.81448012	2086	0.285406122	0.513602962	normal	0.946263155	0.263527904	normal	0.399764912	0.487404021	normal	0.004985598	0.422163761	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06103|0|mcf:102144410|CASK; calcium/calmodulin-dependent serine protein kinase (MAGUK family); K06103 calcium/calmodulin-dependent serine protein kinase [EC:2.7.11.1] (A)	Tight junction (ko04530)	[T]	Signal transduction mechanisms	Protein kinase domain;; Guanylate kinase;; L27 domain;; Protein tyrosine kinase;; PDZ domain (Also known as DHR or GLGF);; Variant SH3 domain;; SH3 domain	Peripheral plasma membrane protein CASK GN=CASK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: peripheral plasma membrane protein CASK isoform X1 [Bubalus bubalis]
ENSG00000147050(KDM6A)	--	4.998274721	491	5.416476091	532	5.202108654	484	5.742511083	546	5.445373796	534	5.58679321	546	0.964797786	0.12198359	normal	0.971619407	-0.015967757	normal	0.957474317	0.165116456	normal	0.765556485	0.088337155	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11447|0|hsa:7403|KDM6A, KABUK2, UTX, bA386N14.2; lysine (K)-specific demethylase 6A; K11447 histone demethylase [EC:1.14.11.-] (A)"	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"JmjC domain, hydroxylase;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Lysine-specific demethylase 6A GN=KDM6A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lysine-specific demethylase 6A-like isoform 3 [Sus scrofa]
ENSG00000147059(SPIN2A)	--	0.176920216	8	0.187467378	7	0.34085429	17	0.268425103	14	0.193902587	8	0.149576339	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: gamete generation (GO:0007276);; 	--	--	--	--	Spin/Ssty Family	Spindlin-2A GN=SPIN2A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: spindlin-2B-like isoform 1 [Dasypus novemcinctus]
ENSG00000147065(MSN)	--	126.4210117	10494	109.9680111	9177	122.750009	10223	209.1650094	17349	194.6720108	15990	155.8630102	12931	0.012860341	0.694375718	normal	0.001267907	0.779550362	normal	0.966905542	0.33068019	normal	0.000518904	0.608285842	normal	--	--	--	K05763|0|pps:100980973|MSN; moesin; K05763 moesin (A)	Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Measles (ko05162);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	Ezrin/radixin/moesin family;; FERM C-terminal PH-like domain;; FERM central domain;; FERM N-terminal domain	Moesin GN=MSN OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: moesin [Oryctolagus cuniculus]
ENSG00000147082(CCNB3)	--	0.694938474	50	0.515623748	33	0.504517012	51	0.168963088	11	0.58410065	40	0.168711895	17	0.000641742	-2.067946185	down	0.977039114	0.245861492	normal	0.03664601	-1.51200523	normal	0.11854626	-0.997971289	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	K05868|0|hsa:85417|CCNB3; cyclin B3; K05868 cyclin B (A)	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115);; Progesterone-mediated oocyte maturation (ko04914)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G2/mitotic-specific cyclin-B3 GN=CCNB3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	"PREDICTED: G2/mitotic-specific cyclin-B3, partial [Equus przewalskii]"
ENSG00000147099(HDAC8)	--	10.73381794	377	10.178617	369	9.813583877	354	13.22058062	406	10.230476	353	12.6343752	393	0.966885162	0.075785292	normal	0.96474695	-0.085022886	normal	0.959138613	0.141912895	normal	0.905275811	0.045200752	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	K11405|0|pps:100988053|HDAC8; histone deacetylase 8; K11405 histone deacetylase 8 [EC:3.5.1.98] (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain	Histone deacetylase 8 GN=HDAC8 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 8 isoform X3 [Mustela putorius furo]
ENSG00000147100(SLC16A2)	--	23.26751611	1631	19.62367007	1378	28.7133109	2016	37.90880708	2648	32.15958001	2239	36.23164007	2551	0.011585876	0.667815946	normal	0.01129742	0.678262748	normal	0.902083211	0.331054567	normal	0.003155501	0.544992978	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08231|0|hsa:6567|SLC16A2, AHDS, DXS128, DXS128E, MCT_7, MCT_8, MCT7, MCT8, MRX22, XPCT; solute carrier family 16, member 2 (thyroid hormone transporter); K08231 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 2 (A)"	Thyroid hormone signaling pathway (ko04919)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 8 GN=SLC16A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: monocarboxylate transporter 8 [Ochotona princeps]
ENSG00000147117(ZNF157)	--	0.18284	8	0.0457886	2	0.0457667	1	0.0228173	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7712|ZNF157, HZF22; zinc finger protein 157; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; NTF2 fold immunity protein;; TFIIH C1-like domain"	Zinc finger protein 157 GN=ZNF157 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 157 [Tupaia chinensis]
ENSG00000147118(ZNF182)	--	3.400636418	258	3.645171998	270	3.602779	264	2.91610002	223	3.26678385	245	3.6501053	277	0.934974156	-0.239622996	normal	0.953849769	-0.160659094	normal	0.965887615	0.060717031	normal	0.773944744	-0.10879986	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101137613|ZNF182; zinc finger protein 182 isoform 1; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Prokaryotic RING finger family 1;; Phorbol esters/diacylglycerol binding domain (C1 domain);; TFIIH C1-like domain;; CpXC protein"	Zinc finger protein 182 GN=ZNF182 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 182 isoform X4 [Equus caballus] 
ENSG00000147119(CHST7)	--	19.4152	641	15.716791	545	19.12824	674	13.284204	474	14.282064	499	11.420466	388	0.512926596	-0.464967939	normal	0.960208504	-0.148212989	normal	0.001281161	-0.802579236	normal	0.011245533	-0.47205851	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	--	--	--	--	Sulfotransferase domain	Carbohydrate sulfotransferase 7 GN=CHST7 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: carbohydrate sulfotransferase 7 [Oryctolagus cuniculus]
ENSG00000147121(KRBOX4)	--	6.133543399	190	7.675053507	198	10.01508043	243	8.047566111	241	7.849951	261	8.775602034	272	0.903905261	0.309971624	normal	0.842004873	0.374623711	normal	0.956276959	0.153455801	normal	0.376442012	0.27429375	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	KRAB box	KRAB domain-containing protein 4 GN=KRBOX4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 674 isoform X1 [Equus przewalskii] 
ENSG00000147123(NDUFB11)	--	59.6592	1152	58.8117	1092	63.2612	1218	58.1842	1103	59.3087	1142	63.29	1216	0.977627009	-0.093412848	normal	0.979717834	0.043104862	normal	0.981798693	-0.010649114	normal	0.947441852	-0.021149849	normal	--	--	--	"K11351|1.2444e-93|nle:100598012|NDUFB11; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa; K11351 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 11 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[S]	Function unknown	ESSS subunit of NADH:ubiquinone oxidoreductase (complex I)	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial (Precursor) GN=NDUFB11 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial isoform 1 [Orcinus orca]"
ENSG00000147124(ZNF41)	--	2.265959315	212	2.625576972	220	2.382110591	217	2.476493338	237	2.268380374	206	3.056219691	286	0.959919306	0.129105315	normal	0.960338722	-0.115465306	normal	0.816121973	0.38766826	normal	0.695026169	0.147018654	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7592|ZNF41, MRX89; zinc finger protein 41; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain;; TFIIH C1-like domain"	Zinc finger protein 41 GN=ZNF41 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 41 isoform X1 [Galeopterus variegatus]
ENSG00000147127(RAB41)	--	0	0	0.1861268	3	0.21008648	1	0.1218877	2	0.12085316	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07896|1.07865e-162|hsa:347517|RAB41; RAB41, member RAS oncogene family; K07896 Ras-related protein Rab-41 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-41 GN=RAB41 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-6B isoform 1 [Ceratotherium simum simum]
ENSG00000147130(ZMYM3)	--	15.97140397	1709	15.45036792	1592	14.76470365	1649	13.54011152	1457	13.61939204	1412	11.9525468	1312	0.944614348	-0.260729579	normal	0.967373299	-0.194330648	normal	0.871838806	-0.337767053	normal	0.120876096	-0.26505991	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	MYM-type Zinc finger with FCS sequence motif;; Domain of unknown function (DUF3504)	Zinc finger MYM-type protein 3 GN=ZMYM3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger MYM-type protein 3 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000147133(TAF1)	--	6.479953535	1107	7.364315907	1267	7.657541405	1243	7.03620976	1164	8.019384922	1302	7.309272633	1248	0.980390029	0.041547337	normal	0.981863945	0.017865331	normal	0.982089904	-0.002496773	normal	0.959389613	0.017296813	normal	[K]	Transcription	Molecular Function: protein binding (GO:0005515);; 	"K03125|0|hsa:6872|TAF1, BA2R, CCG1, CCGS, DYT3, DYT3/TAF1, KAT4, N-TAF1, NSCL2, OF, P250, TAF(II)250, TAF2A, TAFII-250, TAFII250, XDP; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa (EC:2.3.1.48 2.7.11.1); K03125 transcription initiation factor TFIID subunit 1 (A)"	Basal transcription factors (ko03022)	[K]	Transcription	Protein of unknown function (DUF3591);; Bromodomain;; TATA box-binding protein binding;; Zinc knuckle	Transcription initiation factor TFIID subunit 1 GN=TAF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 1 isoform 1 [Ceratotherium simum simum]
ENSG00000147140(NONO)	--	170.6542662	9283	179.9795854	9879	192.4330913	9748	194.2175691	10061	191.2183762	9499	194.211727	9688	0.995529946	0.085264863	normal	0.995473586	-0.078003749	normal	0.996128799	-0.017196152	normal	0.990796408	-0.004533247	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13214|0|ptr:473661|NONO; non-POU domain containing, octamer-binding; K13214 non-POU domain-containing octamer-binding protein (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; NOPS (NUC059) domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Non-POU domain-containing octamer-binding protein GN=NONO OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: non-POU domain-containing octamer-binding protein isoform X1 [Ochotona princeps]
ENSG00000147144(CCDC120)	--	2.774968183	191	2.764698862	216	3.010527389	228	2.410331058	177	2.26967091	176	3.037378879	237	0.959596009	-0.139489512	normal	0.903854909	-0.314438812	normal	0.96617466	0.047254358	normal	0.757051399	-0.126190349	normal	--	--	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF3338)	Coiled-coil domain-containing protein 120 GN=CCDC120 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 120 isoformX2 [Canis lupus familiaris]
ENSG00000147145(LPAR4)	--	0.032656646	1	0	0	0	0	0.260621421	9	0.049005982	1	0.032527506	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04275|0|hsa:2846|LPAR4, GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9; lysophosphatidic acid receptor 4; K04275 lysophosphatidic acid receptor 4 (A)"	Rap1 signaling pathway (ko04015);; Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Pathways in cancer (ko05200)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Lysophosphatidic acid receptor 4 GN=LPAR4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: lysophosphatidic acid receptor 4 [Oryctolagus cuniculus]
ENSG00000147155(EBP)	--	84.549119	1605	70.96141248	1621	92.809451	1971	71.108168	1365	56.491976	1137	112.404485	2194	0.940871079	-0.264229955	normal	0.23073018	-0.532481883	normal	0.980607638	0.146237913	normal	0.77952704	-0.165650044	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sterol metabolic process (GO:0016125);; Molecular Function: cholestenol delta-isomerase activity (GO:0047750);; 	"K01824|8.71426e-148|hsa:10682|EBP, CDPX2, CHO2, CPX, CPXD; emopamil binding protein (sterol isomerase) (EC:5.3.3.5); K01824 cholestenol delta-isomerase [EC:5.3.3.5] (A)"	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	Emopamil binding protein	"3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase GN=EBP OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase [Ailuropoda melanoleuca] "
ENSG00000147162(OGT)	--	40.07520499	4797	37.85727334	4614	36.447539	4348	32.171634	3681	34.60305853	3881	43.215943	5222	0.795182583	-0.41271554	normal	0.967067515	-0.270919169	normal	0.97379926	0.25587776	normal	0.679075247	-0.126314045	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K09667|0|pps:100989146|OGT; O-linked N-acetylglucosamine (GlcNAc) transferase; K09667 protein O-GlcNAc transferase [EC:2.4.1.255] (A)	Other types of O-glycan biosynthesis (ko00514)	[GOT]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Glycosyl transferase family 41;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; NMDA receptor-regulated protein 1;; Tetratricopeptide repeat;; MIT (microtubule interacting and transport) domain;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Est1 DNA/RNA binding domain;; FAT domain"	UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit GN=OGT OS=Homo sapiens (Human) PE=1 SV=3	GOT	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit isoformX1 [Equus caballus] 
ENSG00000147164(SNX12)	--	54.02560522	1883	60.27768015	2096	48.27213401	1731	60.61281	2087	53.345056	1837	60.27580632	2139	0.982704906	0.117474266	normal	0.968349933	-0.211550465	normal	0.92791239	0.296805638	normal	0.790313523	0.065100639	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17918|2.63027e-114|ssc:100155023|SNX12; sorting nexin 12; K17918 sorting nexin-3/12 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain	Sorting nexin-12 GN=SNX12 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-12 isoform X3 [Bos taurus] 
ENSG00000147166(ITGB1BP2)	--	0.38760373	9	0.253513373	6	0.508119122	10	0.470563544	10	0.23262268	4	0.256900078	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16735|0|ptr:465698|ITGB1BP2; integrin beta 1 binding protein (melusin) 2; K16735 integrin beta-1-binding protein 2 (A)	--	[R]	General function prediction only	CHORD;; CS domain	Integrin beta-1-binding protein 2 GN=ITGB1BP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: integrin beta-1-binding protein 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000147168(IL2RG)	--	0	0	0	0	0	0	0	0	0.07661372	0	0.039342689	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05070|0|hsa:3561|IL2RG, CD132, CIDX, IL-2RG, IMD4, P64, SCIDX, SCIDX1; interleukin 2 receptor, gamma; K05070 interleukin 2 receptor gamma (A)"	Cytokine-cytokine receptor interaction (ko04060);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Measles (ko05162);; HTLV-I infection (ko05166);; Inflammatory bowel disease (IBD) (ko05321);; Primary immunodeficiency (ko05340)	--	--	"Interleukin-6 receptor alpha chain, binding;; Erythropoietin receptor, ligand binding;; Fibronectin type III domain"	Cytokine receptor common subunit gamma (Precursor) GN=IL2RG OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: cytokine receptor common subunit gamma [Camelus bactrianus]
ENSG00000147174(GCNA)	--	0.4281096	30	0.282283034	18	0.373414901	24	0.188479473	12	0.183812774	12	0.346296698	23	0.714106115	-1.248501321	normal	--	--	--	0.98715122	-0.065477064	normal	0.412971954	-0.634446471	normal	--	--	--	--	--	[S]	Function unknown	SprT-like family	Acidic repeat-containing protein GN=ACRC OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein PANDA_021120 [Ailuropoda melanoleuca]
ENSG00000147180(ZNF711)	--	2.691190728	212	2.1416866	175	2.210848354	170	2.22404153	165	2.323828587	185	1.58367659	123	0.845283737	-0.389223442	normal	0.96474015	0.058254153	normal	0.778955681	-0.470228348	normal	0.493909195	-0.257891073	normal	[R]	General function prediction only	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: metal ion binding (GO:0046872);; "	--	--	[R]	General function prediction only	"Zfx / Zfy transcription activation region;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc-finger domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 711 GN=ZNF711 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 711 isoform X1 [Galeopterus variegatus]
ENSG00000147202(DIAPH2)	--	5.43287302	708	6.191097141	838	6.068961264	785	6.46471	888	6.433534	833	6.298332791	857	0.900604199	0.295404657	normal	0.976591857	-0.030005994	normal	0.971134949	0.11809331	normal	0.598137803	0.123978103	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	K05741|0|ggo:101152796|protein diaphanous homolog 2-like; K05741 diaphanous 2 (A)	Regulation of actin cytoskeleton (ko04810)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain;; DRF Autoregulatory Domain	Protein diaphanous homolog 2 GN=DIAPH2 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: uncharacterized protein LOC101276728 [Orcinus orca]
ENSG00000147223(RIPPLY1)	--	0.0531548	1	0	0	0	0	0.0526653	1	0.364788	6	0.105506	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transcription Regulator	Protein ripply1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: protein ripply1 [Trichechus manatus latirostris]
ENSG00000147224(PRPS1)	--	57.3461422	1984	50.75957882	1780	55.78444976	1933	59.18458882	2065	56.76881721	1954	39.96984077	1359	0.986800499	0.026877091	normal	0.982019739	0.113034988	normal	0.272257883	-0.516103499	normal	0.755117939	-0.105383218	normal	[FE]	Nucleotide transport and metabolism;; Amino acid transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: ribose phosphate diphosphokinase activity (GO:0004749);; Biological Process: nucleoside metabolic process (GO:0009116);; Biological Process: nucleotide biosynthetic process (GO:0009165);; 	K00948|0|ssc:100517744|PRPS1; phosphoribosyl pyrophosphate synthetase 1; K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] (A)	Pentose phosphate pathway (ko00030);; Purine metabolism (ko00230);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[FE]	Nucleotide transport and metabolism;; Amino acid transport and metabolism	N-terminal domain of ribose phosphate pyrophosphokinase;; Phosphoribosyl synthetase-associated domain;; Phosphoribosyl transferase domain	Ribose-phosphate pyrophosphokinase 1 GN=PRPS1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	"Ribose-phosphate pyrophosphokinase 1, partial [Bos mutus]"
ENSG00000147231(CXorf57)	--	0.158696741	9	0.136823286	9	0.227730358	9	0.030154	2	0.087548353	3	0.044893177	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein CXorf57 GN=CXorf57 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein CXorf57 isoform X3 [Canis lupus familiaris]
ENSG00000147234(FRMPD3)	--	0.113498743	19	0.02574875	4	0.207565362	32	0.261763206	42	0.508673636	80	0.127886894	20	0.673156911	1.054901334	normal	1.54E-13	3.868008171	up	0.955906292	-0.647342138	normal	0.319837303	1.348472076	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	FERM central domain;; PDZ domain (Also known as DHR or GLGF)	FERM and PDZ domain-containing protein 3 GN=FRMPD3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: FERM and PDZ domain-containing protein 3 [Galeopterus variegatus]
ENSG00000147251(DOCK11)	--	3.486487668	460	3.497277761	463	2.676311926	362	2.614699046	338	3.201160393	428	3.9888128	528	0.532112027	-0.473589283	normal	0.960828959	-0.134371314	normal	0.29577822	0.534397675	normal	0.986622528	-0.010192888	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Dedicator of cytokinesis;; C2 domain in Dock180 and Zizimin proteins;; Domain of unknown function (DUF3398);; PH domain	Dedicator of cytokinesis protein 11 GN=DOCK11 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 11 isoform X1 [Galeopterus variegatus]
ENSG00000147255(IGSF1)	--	2.466038969	138	2.35989793	119	2.1969568	115	3.343049969	170	3.22323087	170	3.418470743	182	0.936151164	0.267348641	normal	0.752778914	0.48793402	normal	0.342622822	0.647191082	normal	0.165318086	0.4675935	normal	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain	Immunoglobulin superfamily member 1 (Precursor) GN=IGSF1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 1 isoform X1 [Galeopterus variegatus]
ENSG00000147257(GPC3)	--	0.081095783	2	0	0	0.09045411	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Cellular Component: membrane (GO:0016020);; Molecular Function: heparan sulfate proteoglycan binding (GO:0043395);; 	"K08109|0|hsa:2719|GPC3, DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1; glypican 3; K08109 glypican 3 (OCI-5) (A)"	Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Glypican	Secreted glypican-3 (Precursor) GN=GPC3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: glypican-3 isoform X4 [Equus caballus]
ENSG00000147274(RBMX)	--	115.523725	5378	123.756362	5755	109.676001	5069	114.536254	5750	116.549931	5739	110.768324	5335	0.993406574	0.0656418	normal	0.993829563	-0.025436418	normal	0.993017534	0.065476622	normal	0.907445288	0.032776088	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12885|2.01812e-126|oas:101103540|RBMX; RNA binding motif protein, X-linked; K12885 heterogeneous nuclear ribonucleoprotein G (A)"	Spliceosome (ko03040)	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RBM1CTR (NUC064) family;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"RNA-binding motif protein, X chromosome, N-terminally processed GN=RBMX OS=Homo sapiens (Human) PE=1 SV=3"	A	RNA processing and modification	"PREDICTED: RNA-binding motif protein, X chromosome [Ovis aries]"
ENSG00000147316(MCPH1)	--	5.175853005	330	4.904920019	304	5.404994	346	5.50929	386	5.988647542	420	5.326193	351	0.947398078	0.194464796	normal	0.656549653	0.443009188	normal	0.968696403	0.01235394	normal	0.422754976	0.218315381	normal	--	--	Biological Process: cerebral cortex development (GO:0021987);; 	--	--	[LK]	"Replication, recombination and repair;; Transcription"	Microcephalin protein;; BRCA1 C Terminus (BRCT) domain;; twin BRCT domain	Microcephalin GN=MCPH1 OS=Homo sapiens (Human) PE=1 SV=3	KL	"Transcription;; Replication, recombination and repair"	PREDICTED: microcephalin isoform X1 [Galeopterus variegatus]
ENSG00000147324(MFHAS1)	--	12.76142	1426	14.05438	1590	13.86071	1567	14.63383	1637	15.84765	1766	22.52428	2526	0.973068064	0.168078964	normal	0.979194171	0.129914737	normal	0.008441207	0.68003631	normal	0.332550712	0.35165294	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Malignant fibrous histiocytoma-amplified sequence 1 GN=MFHAS1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: malignant fibrous histiocytoma-amplified sequence 1 isoform X1 [Camelus bactrianus]
ENSG00000147364(FBXO25)	--	7.624609101	505	6.995429477	499	9.24770085	524	6.553021	455	5.620890353	380	8.221338	546	0.952926875	-0.180669651	normal	0.713744457	-0.413027685	normal	0.971385394	0.050898784	normal	0.519449374	-0.166562352	normal	--	--	--	K10305|0|ptr:463956|FBXO25; F-box protein 25; K10305 F-box protein 25/32 (A)	FoxO signaling pathway (ko04068)	[E]	Amino acid transport and metabolism	--	F-box only protein 25 GN=FBXO25 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: F-box only protein 25 isoform X1 [Tupaia chinensis] 
ENSG00000147381(MAGEA4)	--	0	0	0	0	0	0	0.077302028	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 4 GN=MAGEA4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: melanoma-associated antigen 8-like [Galeopterus variegatus]
ENSG00000147383(NSDHL)	--	31.5124059	1053	34.63918291	1160	37.95815941	1233	22.15482307	716	23.954316	786	35.68976482	1164	0.087570121	-0.586261711	normal	0.104550605	-0.582022112	normal	0.97862095	-0.091257966	normal	0.198275848	-0.389799554	normal	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07748|0|hsa:50814|NSDHL, H105E3, SDR31E1, XAP104; NAD(P) dependent steroid dehydrogenase-like (EC:1.1.1.170); K07748 sterol-4alpha-carboxylate 3-dehydrogenase (decarboxylating) [EC:1.1.1.170] (A)"	Steroid biosynthesis (ko00100)	[IE]	Lipid transport and metabolism;; Amino acid transport and metabolism	3-beta hydroxysteroid dehydrogenase/isomerase family;; NAD dependent epimerase/dehydratase family;; NADH(P)-binding;; RmlD substrate binding domain;; Male sterility protein;; Polysaccharide biosynthesis protein;; NmrA-like family	"Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating GN=NSDHL OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating [Ceratotherium simum simum]"
ENSG00000147394(ZNF185)	--	2.730541154	209	2.337810686	199	2.5967524	216	12.9802472	1179	11.59855186	993	4.681618634	394	0	2.456600792	up	0	2.288969067	up	0.001859735	0.854378844	normal	0.015779894	2.016145394	normal	--	--	--	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	--	Zinc finger protein 185 GN=ZNF185 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: zinc finger protein 185 [Galeopterus variegatus]
ENSG00000147400(CETN2)	--	47.44421178	1077	52.95631223	1196	54.43970839	1211	46.39991267	1048	47.41151232	1064	54.087243	1220	0.978408211	-0.070110396	normal	0.963160258	-0.189891052	normal	0.98182107	0.00238787	normal	0.723241561	-0.085005742	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K10840|5.37072e-103|ptr:738502|CETN2; centrin, EF-hand protein, 2; K10840 centrin-2 (A)"	Nucleotide excision repair (ko03420)	[ZD]	"Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning"	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain;; Cytoskeletal-regulatory complex EF hand	Centrin-2 GN=CETN2 OS=Homo sapiens (Human) PE=1 SV=1	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: centrin-2 [Physeter catodon]
ENSG00000147403(RPL10)	--	2629.499237	24265	2338.470682	21609	2303.64357	21571	2805.971679	25190	2734.069771	24685	2609.941787	23884	0.998246358	0.02314056	normal	0.996448448	0.170564603	normal	0.997146089	0.138650731	normal	0.689714633	0.107679775	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02866|2.17847e-157|tup:102492001|RPL10; ribosomal protein L10; K02866 large subunit ribosomal protein L10e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L16p/L10e	60S ribosomal protein L10 GN=RPL10 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L10 [Tupaia chinensis]
ENSG00000147408(CSGALNACT1)	--	23.83171176	1798	27.08631481	1853	25.1119112	1546	33.8180082	2490	32.14107169	2279	37.56491428	2703	0.63193901	0.438600754	normal	0.944575538	0.276907399	normal	0.000294797	0.797132514	normal	0.000518904	0.502533301	normal	--	--	Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: Golgi cisterna membrane (GO:0032580);; 	"K00746|0|hsa:55790|CSGALNACT1, CSGalNAcT-1, ChGn, beta4GalNAcT; chondroitin sulfate N-acetylgalactosaminyltransferase 1 (EC:2.4.1.174); K00746 chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[G]	Carbohydrate transport and metabolism	Chondroitin N-acetylgalactosaminyltransferase;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Chondroitin sulfate N-acetylgalactosaminyltransferase 1 GN=CSGALNACT1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: chondroitin sulfate N-acetylgalactosaminyltransferase 1 [Pteropus alecto] 
ENSG00000147416(ATP6V1B2)	--	29.74940539	1352	36.39651095	1671	30.87280498	1396	33.36250516	1526	35.53110586	1603	38.72580371	1758	0.975780381	0.143673805	normal	0.982550089	-0.081288746	normal	0.892885273	0.324031228	normal	0.55926066	0.124282023	normal	[C]	Energy production and conversion	Molecular Function: ATP binding (GO:0005524);; Biological Process: proton transport (GO:0015992);; Biological Process: ATP metabolic process (GO:0046034);; 	"K02147|0|pps:100986037|ATP6V1B2; ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; K02147 V-type H+-transporting ATPase subunit B (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	"ATP synthase alpha/beta family, nucleotide-binding domain;; ATP synthase alpha/beta chain, C terminal domain;; ATP synthase alpha/beta family, beta-barrel domain"	"V-type proton ATPase subunit B, brain isoform GN=ATP6V1B2 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: V-type proton ATPase subunit B, brain isoform [Tupaia chinensis]"
ENSG00000147419(CCDC25)	--	15.962309	963	14.40292	867	15.38259	912	18.07177	1099	19.44388	1164	16.61486	999	0.968218608	0.159513074	normal	0.723190261	0.402952045	normal	0.972633418	0.122964533	normal	0.22134578	0.229131422	normal	--	--	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF814)	Coiled-coil domain-containing protein 25 GN=CCDC25 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 25 [Odobenus rosmarus divergens] 
ENSG00000147421(HMBOX1)	--	5.633473292	521	5.695826905	551	6.255652302	517	4.659493502	478	5.219032146	449	6.111120461	578	0.959134743	-0.154628732	normal	0.876902363	-0.315801366	normal	0.960757009	0.152192541	normal	0.730012906	-0.099085686	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	--	--	--	--	"Hepatocyte nuclear factor 1 (HNF-1), N terminus;; Homeobox domain;; Homeobox KN domain"	Homeobox-containing protein 1 GN=HMBOX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox-containing protein 1 isoform X2 [Oryctolagus cuniculus]
ENSG00000147432(CHRNB3)	--	0	0	0.077499601	3	0	0	0	0	0	0	0.102575664	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04814|0|ptr:464500|CHRNB3; cholinergic receptor, nicotinic, beta 3 (neuronal); K04814 nicotinic acetylcholine receptor beta-3 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Neuronal acetylcholine receptor subunit beta-3 (Precursor) GN=CHRNB3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: neuronal acetylcholine receptor subunit beta-3 [Ceratotherium simum simum]
ENSG00000147439(BIN3)	--	11.52083019	396	12.92311422	374	12.272189	405	15.071425	460	14.73025052	484	13.14379969	455	0.950935904	0.184636065	normal	0.838184624	0.349297646	normal	0.957030219	0.159092445	normal	0.351713561	0.230649335	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	BAR domain;; Vps5 C terminal like	Bridging integrator 3 GN=BIN3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: bridging integrator 3 isoform X1 [Galeopterus variegatus]
ENSG00000147443(DOK2)	--	0	0	0.0269906	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	--	--	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type)	Docking protein 2 GN=DOK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: docking protein 2 [Equus przewalskii]
ENSG00000147454(SLC25A37)	--	25.997529	2626	24.31964	2466	24.004254	2403	33.044955	3349	30.132302	2961	32.431372	3101	0.926086415	0.319865141	normal	0.966364302	0.242349345	normal	0.873746958	0.359405811	normal	0.057888957	0.306862522	normal	--	--	--	"K15113|0|hsa:51312|SLC25A37, MFRN, MFRN1, MSC, MSCP, PRO1278, PRO1584, PRO2217; solute carrier family 25 (mitochondrial iron transporter), member 37; K15113 solute carrier family 25 (mitochondrial iron transporter), member 28/37 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitoferrin-1 GN=SLC25A37 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: mitoferrin-1 [Loxodonta africana]
ENSG00000147457(CHMP7)	--	18.69846772	1194	17.99127721	1179	18.25076124	1190	19.95387747	1283	20.58907982	1298	17.74253546	1125	0.980108434	0.072795697	normal	0.976382784	0.11715685	normal	0.978332359	-0.089211394	normal	0.900681346	0.035240778	normal	--	--	Biological Process: vacuolar transport (GO:0007034);; 	K15053|0|hsa:91782|CHMP7; charged multivesicular body protein 7; K15053 charged multivesicular body protein 7 (A)	Endocytosis (ko04144)	[S]	Function unknown	Snf7	Charged multivesicular body protein 7 GN=CHMP7 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 7 [Tupaia chinensis]
ENSG00000147459(DOCK5)	--	44.33760154	6109	51.36075056	7172	44.76356195	6650	41.74088279	5319	36.86874269	5164	40.47405442	5943	0.9822239	-0.230551261	normal	0.543193503	-0.495189391	normal	0.989947431	-0.170413384	normal	0.081338262	-0.299942742	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17707|0|hsa:80005|DOCK5; dedicator of cytokinesis 5; K17707 dedicator of cytokinesis protein 5 (A)	--	[T]	Signal transduction mechanisms	C2 domain in Dock180 and Zizimin proteins;; Dedicator of cytokinesis;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Dedicator of cytokinesis protein 5 GN=DOCK5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 5 [Mustela putorius furo] 
ENSG00000147465(STAR)	--	0	0	0	0	0.078518596	1	0.117960534	4	0.086628985	2	0.19630371	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: lipid binding (GO:0008289);; 	"K16931|0|hsa:6770|STAR, STARD1; steroidogenic acute regulatory protein; K16931 steroidogenic acute regulatory protein, mitochondrial (A)"	Ovarian steroidogenesis (ko04913)	[I]	Lipid transport and metabolism	START domain	"Steroidogenic acute regulatory protein, mitochondrial (Precursor) GN=STAR OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: steroidogenic acute regulatory protein, mitochondrial [Eptesicus fuscus]"
ENSG00000147471(PROSC)	--	25.2789885	944	19.55192856	800	28.42020241	983	25.34781835	1060	28.79706868	917	24.70355569	909	0.971497311	0.136164025	normal	0.961787779	0.175185677	normal	0.972732095	-0.121008914	normal	0.824138446	0.060309212	normal	[R]	General function prediction only	--	K06997|0|hsa:11212|PROSC; proline synthetase co-transcribed homolog (bacterial); K06997 (A)	--	[R]	General function prediction only	"Alanine racemase, N-terminal domain"	Proline synthase co-transcribed bacterial homolog protein GN=PROSC OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: proline synthase co-transcribed bacterial homolog protein [Myotis brandtii] 
ENSG00000147475(ERLIN2)	--	15.29078593	1286	14.7439955	1117	13.67046463	1146	12.90549003	1161	15.10866544	1164	15.51165574	1340	0.967431917	-0.178130814	normal	0.98011248	0.037984936	normal	0.95738671	0.217069362	normal	0.93492335	0.025574482	normal	--	--	--	--	--	[R]	General function prediction only	SPFH domain / Band 7 family	Erlin-2 GN=ERLIN2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: erlin-2 [Oryctolagus cuniculus] 
ENSG00000147485(PXDNL)	--	0	0	0	0	0	0	0	0	0.079215571	2	0.010414	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Animal haem peroxidase;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Leucine rich repeat;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Leucine Rich repeats (2 copies);; CD80-like C2-set immunoglobulin domain;; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; von Willebrand factor type C domain;; Beta-microseminoprotein (PSP-94)	Peroxidasin-like protein (Precursor) GN=PXDNL OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: peroxidasin-like protein [Odobenus rosmarus divergens]
ENSG00000147488(ST18)	--	0.008061352	1	0	0	0	0	0.016178675	2	0.023461254	2	0.032046946	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	--	--	[K]	Transcription	"Myelin transcription factor 1;; Zinc finger, C2HC type"	Suppression of tumorigenicity 18 protein GN=ST18 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: suppression of tumorigenicity 18 protein isoform X1 [Canis lupus familiaris] 
ENSG00000147509(RGS20)	--	10.29668075	225	14.74023861	326	13.27194141	304	6.8827743	169	5.073131969	126	6.875944967	150	0.765640306	-0.44025183	normal	1.95E-08	-1.382162777	down	0.00016103	-1.020025142	down	0.000209713	-0.96370294	normal	--	--	--	K16449|1.75581e-177|pps:100971603|RGS20; regulator of G-protein signaling 20; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 20 GN=RGS20 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 20 [Equus caballus]
ENSG00000147526(TACC1)	--	22.08896458	2487	23.57151963	2692	23.8316917	2787	25.90887909	2990	24.33062261	2744	23.0726526	2718	0.968611091	0.234774292	normal	0.989175593	0.00617208	normal	0.989158125	-0.044434572	normal	0.794544555	0.064055165	normal	--	--	--	"K14281|0|ptr:464124|TACC1; transforming, acidic coiled-coil containing protein 1; K14281 transforming acidic coiled-coil-containing protein 1 (A)"	--	--	--	Transforming acidic coiled-coil-containing protein (TACC)	Transforming acidic coiled-coil-containing protein 1 GN=TACC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transforming acidic coiled-coil-containing protein 1 [Galeopterus variegatus]
ENSG00000147533(GOLGA7)	--	35.39059854	977	34.10553531	941	38.78052945	1058	34.74105322	962	32.286854	890	37.6109856	1015	0.978116795	-0.053069823	normal	0.973770997	-0.10164794	normal	0.978285579	-0.068052022	normal	0.770554066	-0.074712809	normal	--	--	--	--	--	[S]	Function unknown	Golgin subfamily A member 7/ERF4 family	Golgin subfamily A member 7 GN=GOLGA7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: golgin subfamily A member 7 isoform 2 [Ovis aries]
ENSG00000147535(PLPP5)	--	12.07883332	216	12.53855689	227	11.53589686	226	15.2799545	322	17.68532178	344	15.21920764	308	0.403433628	0.542020864	normal	0.289289657	0.575156502	normal	0.719410001	0.435808589	normal	0.029156125	0.520669448	normal	[I]	Lipid transport and metabolism	--	--	--	[I]	Lipid transport and metabolism	PAP2 superfamily	Phosphatidate phosphatase PPAPDC1B GN=PPAPDC1B OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: phosphatidate phosphatase PPAPDC1B [Trichechus manatus latirostris]
ENSG00000147536(GINS4)	--	19.495178	1319	21.856071	1470	20.453627	1389	14.64894301	937	12.46913685	884	13.0882903	827	0.240012809	-0.52342852	normal	0.001821348	-0.754112608	normal	0.001437294	-0.75530086	normal	2.71E-06	-0.679503473	normal	[S]	Function unknown	--	"K10735|3.77034e-149|hsa:84296|GINS4, SLD5; GINS complex subunit 4 (Sld5 homolog); K10735 GINS complex subunit 4 (A)"	--	[L]	"Replication, recombination and repair"	GINS complex protein	"DNA replication complex GINS protein SLD5, N-terminally processed GN=GINS4 OS=Homo sapiens (Human) PE=1 SV=1"	L	"Replication, recombination and repair"	PREDICTED: DNA replication complex GINS protein SLD5 [Eptesicus fuscus]
ENSG00000147548(NSD3)	--	19.7924714	1925	18.06790223	1931	16.875929	1857	21.70577967	2078	19.81035101	2008	22.34271914	1911	0.985148563	0.07944391	normal	0.986066766	0.0349577	normal	0.986039444	0.033036	normal	0.851871876	0.048488567	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11425|0|pps:100989573|WHSC1L1; Wolf-Hirschhorn syndrome candidate 1-like 1; K11425 histone-lysine N-methyltransferase NSD3 [EC:2.1.1.43] (A)	Lysine degradation (ko00310)	[K]	Transcription	PWWP domain;; SET domain;; PHD-finger	Histone-lysine N-methyltransferase NSD3 GN=WHSC1L1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone-lysine N-methyltransferase NSD3 isoform X2 [Galeopterus variegatus]
ENSG00000147570(DNAJC5B)	--	0.129732	3	0.0429702	1	0.279887	3	0	0	0	0	0.306805066	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09525|7.42192e-130|hsa:85479|DNAJC5B, CSP-beta; DnaJ (Hsp40) homolog, subfamily C, member 5 beta; K09525 DnaJ homolog subfamily C member 5 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 5B GN=DNAJC5B OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 5B isoform X1 [Mustela putorius furo] 
ENSG00000147571(CRH)	--	0.128652	3	0.169314	4	0.247226	5	0.127857	3	0.0413572	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05256|2.99864e-46|ptr:464215|CRH; corticotropin releasing hormone; K05256 corticotropin-releasing hormone (A)	Long-term depression (ko04730);; Alcoholism (ko05034)	--	--	Corticotropin-releasing factor family	Corticoliberin (Precursor) GN=CRH OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: corticoliberin [Leptonychotes weddellii]
ENSG00000147573(TRIM55)	--	0.093390084	5	0.158571272	8	0.241036547	5	0.08004807	5	0.090235243	3	0.096149275	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K10654|0|cjc:100409202|TRIM55; tripartite motif containing 55; K10654 tripartite motif-containing protein 55 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; RING-type zinc-finger;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; zinc-RING finger domain"	Tripartite motif-containing protein 55 GN=TRIM55 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 55 isoformX1 [Canis lupus familiaris]
ENSG00000147576(ADHFE1)	--	54.9453751	1861	51.6561958	1815	54.05989531	1904	50.05543207	1724	52.7067507	1780	43.90594057	1500	0.979199754	-0.141029528	normal	0.984826761	-0.049477235	normal	0.856615396	-0.352046606	normal	0.347590057	-0.178659458	normal	[C]	Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K11173|0|hsa:137872|ADHFE1, ADH8, HOT; alcohol dehydrogenase, iron containing, 1 (EC:1.1.99.24); K11173 hydroxyacid-oxoacid transhydrogenase [EC:1.1.99.24] (A)"	--	[C]	Energy production and conversion	Iron-containing alcohol dehydrogenase;; Iron-containing alcohol dehydrogenase	"Hydroxyacid-oxoacid transhydrogenase, mitochondrial (Precursor) GN=ADHFE1 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: hydroxyacid-oxoacid transhydrogenase, mitochondrial isoform X2 [Mustela putorius furo] "
ENSG00000147586(MRPS28)	--	56.5736366	434	52.7521984	452	62.36521989	496	52.93331559	438	84.34883301	550	49.6986309	418	0.970296291	-0.017534646	normal	0.920915702	0.26088993	normal	0.924497923	-0.254282985	normal	0.997888878	0.003851283	normal	--	--	--	"K17407|2.95461e-111|hsa:28957|MRPS28, MRP-S28, MRP-S35, MRPS35; mitochondrial ribosomal protein S28; K17407 small subunit ribosomal protein S28 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal protein MRP-S35	"28S ribosomal protein S28, mitochondrial (Precursor) GN=MRPS28 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S28, mitochondrial isoform X2 [Camelus ferus]"
ENSG00000147588(PMP2)	--	0	0	0.111465051	5	0	0	0	0	0	0	0.053656867	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family	Myelin P2 protein GN=PMP2 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: myelin P2 protein [Ailuropoda melanoleuca] 
ENSG00000147592(LACTB2)	--	34.4953	641	37.8505	712	41.6889	735	76.8551	1424	84.6669	1537	84.2674	1569	1.04E-08	1.118875903	up	4.85E-08	1.087132462	up	2.86E-08	1.084174792	up	2.92E-15	1.096640512	up	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Metallo-beta-lactamase superfamily	Beta-lactamase-like protein 2 GN=LACTB2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: beta-lactamase-like protein 2 [Bison bison bison]
ENSG00000147601(TERF1)	--	14.53571054	639	16.20416	654	15.7334357	684	14.3464973	634	14.1275241	595	14.469906	657	0.973555356	-0.042063816	normal	0.960733258	-0.157445649	normal	0.973105811	-0.066244941	normal	0.745972401	-0.088998895	normal	--	--	Molecular Function: telomeric DNA binding (GO:0042162);; Molecular Function: protein homodimerization activity (GO:0042803);; 	K11110|0|ptr:745755|TERF1; telomeric repeat binding factor (NIMA-interacting) 1; K11110 telomeric repeat-binding factor 1 (A)	--	--	--	Telomere repeat binding factor (TRF);; Myb-like DNA-binding domain;; Myb-like DNA-binding domain	Telomeric repeat-binding factor 1 GN=TERF1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: telomeric repeat-binding factor 1 isoform X1 [Equus przewalskii]
ENSG00000147604(RPL7)	--	1288.73537	19841	1245.092915	19793	1254.45436	19288	1494.219774	22623	1395.321547	20789	1319.205719	19786	0.996615802	0.158461755	normal	0.997719817	0.049399826	normal	0.997814962	0.028482779	normal	0.779435951	0.079418874	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02937|2.08455e-155|pon:100172811|RPL7; ribosomal protein L7; K02937 large subunit ribosomal protein L7e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L30 N-terminal domain;; Ribosomal protein L30p/L7e	60S ribosomal protein L7 GN=RPL7 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L7 [Dasypus novemcinctus]
ENSG00000147606(SLC26A7)	--	0.333595631	5	0.1347555	3	0.744847022	3	0.131562008	2	0.030068792	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13962|0|nle:100588176|SLC26A7; solute carrier family 26, member 7; K13962 solute carrier family 26 (anion exchange transporter), member 7 (A)"	Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain	Anion exchange transporter OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: anion exchange transporter [Galeopterus variegatus]
ENSG00000147614(ATP6V0D2)	--	0.079483137	3	0.160876053	6	0.079833679	2	0.184668835	7	0.179480323	6	1.076003953	41	--	--	--	--	--	--	1.08E-06	3.59103878	up	--	--	--	[C]	Energy production and conversion	--	"K02146|0|ptr:472809|ATP6V0D2; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; K02146 V-type H+-transporting ATPase subunit d (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Tuberculosis (ko05152);; Viral carcinogenesis (ko05203);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase (C/AC39) subunit	V-type proton ATPase subunit d 2 GN=ATP6V0D2 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit d 2 [Galeopterus variegatus]
ENSG00000147642(SYBU)	--	4.468076064	213	3.575610395	174	6.004352044	195	3.471413332	176	2.910139568	145	3.516149209	168	0.911881841	-0.303695936	normal	0.927977367	-0.281774039	normal	0.945130426	-0.221452221	normal	0.450305234	-0.272545649	normal	--	--	--	--	--	--	--	Golgi-localised syntaxin-1-binding clamp	Syntabulin GN=SYBU OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: syntabulin isoform X1 [Loxodonta africana] 
ENSG00000147647(DPYS)	--	0	0	0	0	0	0	0	0	0.024724592	0	0.050531708	2	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K01464|0|hsa:1807|DPYS, DHP, DHPase; dihydropyrimidinase (EC:3.5.2.2); K01464 dihydropyrimidinase [EC:3.5.2.2] (A)"	Pyrimidine metabolism (ko00240);; beta-Alanine metabolism (ko00410);; Pantothenate and CoA biosynthesis (ko00770);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Amidohydrolase family;; Amidohydrolase;; Amidohydrolase;; Amidohydrolase family	Dihydropyrimidinase GN=DPYS OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: dihydropyrimidinase [Dasypus novemcinctus]
ENSG00000147649(MTDH)	--	39.75118573	4028	42.54338273	4109	41.06179238	3950	45.20858424	4666	43.95585158	4376	40.56441332	3968	0.985568375	0.181226093	normal	0.991489211	0.069374107	normal	0.992087486	-0.001731408	normal	0.720804296	0.084438221	normal	--	--	Biological Process: negative regulation of apoptotic process (GO:0043066);; Biological Process: positive regulation of I-kappaB kinase/NF-kappaB signaling (GO:0043123);; Biological Process: positive regulation of angiogenesis (GO:0045766);; 	--	--	--	--	--	Protein LYRIC GN=MTDH OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein LYRIC isoform X2 [Mustela putorius furo]
ENSG00000147650(LRP12)	--	20.02702	1162	15.28917428	1004	16.52865	953	13.28995	800	16.10983	927	12.10287	708	0.117147842	-0.568458713	normal	0.970575648	-0.136330801	normal	0.598037094	-0.436212137	normal	0.035889847	-0.378778487	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	CUB domain;; Low-density lipoprotein receptor domain class A	Low-density lipoprotein receptor-related protein 12 (Precursor) GN=LRP12 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 12 isoform 1 [Odobenus rosmarus divergens]
ENSG00000147654(EBAG9)	--	13.26617059	401	11.66290962	374	13.39539543	391	13.19808084	397	12.95426857	399	12.96186122	402	0.968765651	-0.045121737	normal	0.966269515	0.071643426	normal	0.969283721	0.031614856	normal	0.970761413	0.017943881	normal	--	--	--	--	--	--	--	--	Receptor-binding cancer antigen expressed on SiSo cells GN=EBAG9 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	hypothetical protein PANDA_021796 [Ailuropoda melanoleuca]
ENSG00000147669(POLR2K)	--	44.022065	591	49.846475	672	54.37335	723	57.748641	799	56.749274	757	48.007878	657	0.708459465	0.403300467	normal	0.963961958	0.150087141	normal	0.964780161	-0.146073065	normal	0.577046864	0.13460622	normal	[K]	Transcription	--	"K03009|4.69255e-33|mze:101476521|DNA-directed RNA polymerases I, II, and III subunit RPABC4-like; K03009 DNA-directed RNA polymerases I, II, and III subunit RPABC4 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623)	[K]	Transcription	"DNA directed RNA polymerase, 7 kDa subunit"	"DNA-directed RNA polymerases I, II, and III subunit RPABC4 GN=POLR2K OS=Homo sapiens (Human) PE=2 SV=1"	K	Transcription	"DNA-directed RNA polymerases I, II, and III subunit RPABC4 [Pteropus alecto]"
ENSG00000147676(MAL2)	--	0.422444395	15	0.405981035	15	0.108488356	3	0.269935174	10	1.288613328	47	2.019906119	75	--	--	--	0.055362582	1.534698926	normal	1.58E-13	4.076940825	up	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	Protein MAL2 GN=MAL2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	hypothetical protein PANDA_020561 [Ailuropoda melanoleuca]
ENSG00000147677(EIF3H)	--	229.91365	3682	228.032757	3623	239.9485601	3782	239.0244	3919	243.3989644	4088	235.240509	3972	0.991245089	0.059139762	normal	0.986776496	0.152723792	normal	0.991288858	0.062400468	normal	0.696162203	0.090578245	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03247|0|ptr:464344|EIF3H, EIF3S3; eukaryotic translation initiation factor 3, subunit H; K03247 translation initiation factor 3 subunit H (A)"	RNA transport (ko03013);; Measles (ko05162)	[J]	"Translation, ribosomal structure and biogenesis"	JAB1/Mov34/MPN/PAD-1 ubiquitin protease	Eukaryotic translation initiation factor 3 subunit H {ECO:0000255|HAMAP-Rule:MF_03007} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit H isoform 1 [Dasypus novemcinctus]
ENSG00000147679(UTP23)	--	9.58063	473	7.1481419	410	11.561311	441	13.40357	562	9.96841	514	8.867341	477	0.942167686	0.217249687	normal	0.889102264	0.303715544	normal	0.965805472	0.104574283	normal	0.389960109	0.208490983	normal	[R]	General function prediction only	Cellular Component: small-subunit processome (GO:0032040);; 	"K14773|1.17074e-167|hsa:84294|UTP23, C8orf53; UTP23, small subunit (SSU) processome component, homolog (yeast); K14773 U3 small nucleolar RNA-associated protein 23 (A)"	--	[R]	General function prediction only	Fcf1	rRNA-processing protein UTP23 homolog GN=UTP23 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rRNA-processing protein UTP23 homolog [Felis catus]
ENSG00000147684(NDUFB9)	--	140.469248	1259	134.760923	1238	138.040783	1269	168.978874	1582	169.787912	1515	143.298662	1299	0.915009431	0.298313717	normal	0.936447108	0.26958181	normal	0.982211789	0.025388015	normal	0.276354456	0.201441633	normal	--	--	--	"K03965|8.27879e-96|ptr:464380|NDUFB9; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa; K03965 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 9 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Complex 1 protein (LYR family);; Complex1_LYR-like	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 GN=NDUFB9 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 [Ceratotherium simum simum]
ENSG00000147687(TATDN1)	--	31.79483303	423	34.916632	430	32.529556	427	28.35363224	395	30.6371822	404	30.254224	402	0.961596907	-0.129151674	normal	0.963347905	-0.11100507	normal	0.965870429	-0.094985241	normal	0.713277133	-0.113033311	normal	[L]	"Replication, recombination and repair"	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	K03424|0|pps:100978389|TATDN1; TatD DNase domain containing 1; K03424 TatD DNase family protein [EC:3.1.21.-] (A)	--	[L]	"Replication, recombination and repair"	TatD related DNase	Putative deoxyribonuclease TATDN1 GN=TATDN1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	TatD DNase domain containing 1 [Sus scrofa]
ENSG00000147689(FAM83A)	--	0.239212525	16	0.110810655	7	0.097755053	7	0.199959577	10	0.425843042	41	0.143930939	14	--	--	--	0.001210876	2.301119773	up	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF1669)	Protein FAM83A GN=FAM83A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM83A [Bubalus bubalis]
ENSG00000147697(GSDMC)	--	0.090128945	3	0.089585998	3	0	0	0.059580984	2	0.06019366	2	0.05951635	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Gasdermin family	Gasdermin-C GN=GSDMC OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: gasdermin-C [Felis catus]
ENSG00000147789(ZNF7)	--	14.93941217	594	13.29991391	513	11.37366728	493	12.36556648	528	11.87968271	505	12.28254891	531	0.949008678	-0.200207571	normal	0.970382009	-0.043971347	normal	0.967522117	0.098541456	normal	0.871638016	-0.05419289	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7553|ZNF7, HF.16, KOX4, zf30; zinc finger protein 7; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain"	Zinc finger protein 7 GN=ZNF7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 7 [Galeopterus variegatus]
ENSG00000147799(ARHGAP39)	--	30.75192558	1725	27.842548	1647	27.37918838	1793	21.82770988	1563	22.98835341	1465	23.08447007	1479	0.973397037	-0.172948925	normal	0.968942272	-0.190181164	normal	0.930278073	-0.285779051	normal	0.223748124	-0.217854139	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	RhoGAP domain;; MyTH4 domain;; WW domain	Rho GTPase-activating protein 39 GN=ARHGAP39 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 39 [Odobenus rosmarus divergens]
ENSG00000147804(SLC39A4)	--	8.048756274	248	6.382319895	202	7.420687696	243	6.414327174	195	7.804581414	235	4.521917096	138	0.844654748	-0.375070449	normal	0.947570249	0.195520784	normal	0.019675476	-0.817735632	normal	0.355994337	-0.308707744	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14710|0|pps:100990959|SLC39A4; solute carrier family 39 (zinc transporter), member 4; K14710 solute carrier family 39 (zinc transporter), member 4 (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP4 (Precursor) GN=SLC39A4 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP4 [Ceratotherium simum simum]
ENSG00000147813(NAPRT)	--	2.186130209	64	3.065722641	86	3.608419935	110	5.510541456	166	7.160017	213	5.659837636	170	3.50E-05	1.32377574	up	1.24E-05	1.27233687	up	0.471416006	0.612910579	normal	0.000336933	1.057968721	up	[H]	Coenzyme transport and metabolism	--	"K00763|0|ptr:739858|NAPRT, NAPRT1; nicotinate phosphoribosyltransferase; K00763 nicotinate phosphoribosyltransferase [EC:6.3.4.21] (A)"	Nicotinate and nicotinamide metabolism (ko00760)	[H]	Coenzyme transport and metabolism	Nicotinate phosphoribosyltransferase (NAPRTase) family	Nicotinate phosphoribosyltransferase GN=NAPRT OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: nicotinate phosphoribosyltransferase [Eptesicus fuscus]
ENSG00000147852(VLDLR)	--	13.613709	1052	12.81973614	1092	13.1747612	1168	15.1041612	1259	13.72557623	1101	26.80735898	2246	0.951666483	0.228006609	normal	0.980133445	-0.009571744	normal	3.68E-06	0.934138691	normal	0.490810223	0.456527201	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain	Very low-density lipoprotein receptor (Precursor) GN=VLDLR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: very low-density lipoprotein receptor isoform X1 [Galeopterus variegatus]
ENSG00000147853(AK3)	--	47.51485558	1956	42.05763177	1746	51.7395352	2075	51.49824941	2138	47.97917731	2008	46.4959028	1946	0.984433508	0.097449991	normal	0.974082877	0.180133574	normal	0.984059396	-0.100815182	normal	0.828193378	0.055344695	normal	[F]	Nucleotide transport and metabolism	Molecular Function: adenylate kinase activity (GO:0004017);; 	"K00944|1.32705e-166|ggo:101147145|AK3; GTP:AMP phosphotransferase, mitochondrial isoform 1; K00944 nucleoside-triphosphate--adenylate kinase [EC:2.7.4.10] (A)"	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	"Adenylate kinase;; Adenylate kinase, active site lid;; AAA domain;; AAA domain"	"GTP:AMP phosphotransferase AK3, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03169} OS=Homo sapiens (Human) PE=1 SV=4"	F	Nucleotide transport and metabolism	"PREDICTED: GTP:AMP phosphotransferase AK3, mitochondrial isoform X1 [Physeter catodon] "
ENSG00000147854(UHRF2)	--	12.499777	958	15.163488	1181	15.376818	1150	17.301635	1311	14.201104	1086	17.408656	1355	0.654868012	0.421158426	normal	0.972153432	-0.142221432	normal	0.953612326	0.228090934	normal	0.428380067	0.168924171	normal	[V]	Defense mechanisms	Molecular Function: protein binding (GO:0005515);; Molecular Function: histone binding (GO:0042393);; 	"K15713|0|hsa:115426|UHRF2, NIRF, RNF107, URF2; ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase; K15713 E3 ubiquitin-protein ligase UHRF2 [EC:6.3.2.19] (A)"	--	--	--	SAD/SRA domain;; Protein of unknown function (DUF3590);; PHD-finger;; Ubiquitin family	E3 ubiquitin-protein ligase UHRF2 GN=UHRF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: E3 ubiquitin-protein ligase UHRF2 [Tupaia chinensis]
ENSG00000147862(NFIB)	--	8.567094079	1201	9.753129442	1364	8.832257894	1217	7.487417058	1005	6.781168541	950	7.494336586	1056	0.915974319	-0.287470234	normal	0.198206289	-0.542545769	normal	0.956992636	-0.212726741	normal	0.032443735	-0.350095999	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09169|0|ngi:103746572|Nfib; nuclear factor I/B; K09169 nuclear factor I/B (A)	--	[K]	Transcription	CTF/NF-I family transcription modulation region;; Nuclear factor I protein pre-N-terminus;; MH1 domain	Nuclear factor 1 B-type GN=NFIB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear factor 1 B-type isoform X1 [Ochotona princeps]
ENSG00000147872(PLIN2)	--	125.9492252	4699	125.4663453	4635	100.5552912	3714	90.4454154	3429	61.79911401	2306	115.6196101	4354	0.496938075	-0.485211536	normal	1.18E-07	-1.02811769	down	0.978837101	0.22099296	normal	0.305214581	-0.3920134	normal	--	--	--	"K17284|0|hsa:123|PLIN2, ADFP, ADRP; perilipin 2; K17284 perilipin-2 (A)"	--	--	--	Perilipin family	Perilipin-2 GN=PLIN2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: perilipin-2 [Galeopterus variegatus]
ENSG00000147874(HAUS6)	--	27.43461672	2958	30.18450554	3190	28.98955193	3008	20.8857515	2257	18.84318751	1992	20.818636	2185	0.717969685	-0.420796797	normal	0.006305339	-0.700341058	normal	0.517998009	-0.469184742	normal	0.000224008	-0.53039648	normal	--	--	--	"K16589|0|ptr:473117|HAUS6; HAUS augmin-like complex, subunit 6; K16589 HAUS augmin-like complex subunit 6 (A)"	--	--	--	HAUS augmin-like complex subunit 6 N-terminus	HAUS augmin-like complex subunit 6 GN=HAUS6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: HAUS augmin-like complex subunit 6 [Ceratotherium simum simum]
ENSG00000147894(C9orf72)	--	4.672871623	202	4.33625752	194	3.483678302	151	4.087789425	174	4.146224664	157	4.296331084	179	0.938053805	-0.244097472	normal	0.903694537	-0.323906082	normal	0.943554119	0.23495596	normal	0.787087247	-0.122647403	normal	--	--	--	--	--	--	--	C9orf72-like protein family	Protein C9orf72 GN=C9orf72 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein C9orf72 homolog [Erinaceus europaeus]
ENSG00000147905(ZCCHC7)	--	7.098002001	363	7.505869598	388	8.5716325	432	8.9617162	460	7.051386	345	8.692632	437	0.88386184	0.309665519	normal	0.947897434	-0.190100536	normal	0.970477461	0.0082817	normal	0.895442474	0.048979454	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	"K12597|0|hsa:84186|ZCCHC7, AIR1; zinc finger, CCHC domain containing 7; K12597 protein AIR1/2 (A)"	RNA degradation (ko03018)	[O]	"Posttranslational modification, protein turnover, chaperones"	Zinc knuckle	Zinc finger CCHC domain-containing protein 7 GN=ZCCHC7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: zinc finger CCHC domain-containing protein 7 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000147912(FBXO10)	--	3.36813224	331	3.978726002	397	4.32033077	346	3.107346398	304	3.920845805	383	4.771628097	470	0.956420144	-0.152851488	normal	0.966261049	-0.072938275	normal	0.664312229	0.431971272	normal	0.843804337	0.087391048	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10296|0|ggo:101132330|FBXO10; F-box only protein 10; K10296 F-box protein 10 (A)	--	[R]	General function prediction only	Right handed beta helix region;; Periplasmic copper-binding protein (NosD);; F-box-like;; F-box domain	F-box only protein 10 GN=FBXO10 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: F-box only protein 10 [Ailuropoda melanoleuca] 
ENSG00000147955(SIGMAR1)	--	77.962025	2215	81.13875	2266	81.537574	2357	93.429419	2606	86.455896	2375	91.085139	2566	0.973894981	0.203567836	normal	0.987357784	0.046322897	normal	0.98533249	0.114207722	normal	0.566941688	0.121140728	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	ERG2 and Sigma1 receptor like protein	Sigma non-opioid intracellular receptor 1 GN=SIGMAR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: sigma non-opioid intracellular receptor 1 isoform X1 [Tupaia chinensis] 
ENSG00000147996(CBWD5)	--	13.67119257	342	13.55266809	360	11.37050326	297	12.913613	351	14.8258666	348	13.35699388	340	0.968610299	0.006613117	normal	0.965707996	-0.070036896	normal	0.949629854	0.185895087	normal	0.93492335	0.035059523	normal	[R]	General function prediction only	--	--	--	[H]	Coenzyme transport and metabolism	"CobW/HypB/UreG, nucleotide-binding domain;; Cobalamin synthesis protein cobW C-terminal domain;; Elongation factor Tu GTP binding domain"	COBW domain-containing protein 5 GN=CBWD5 OS=Homo sapiens (Human) PE=2 SV=1	H	Coenzyme transport and metabolism	PREDICTED: COBW domain-containing protein 2 isoform X4 [Canis lupus familiaris]
ENSG00000148019(CEP78)	--	12.55495624	1064	12.14350762	1143	14.53311129	1295	13.95481304	1364	12.66413651	1142	11.70649439	1116	0.877626558	0.32709518	normal	0.980463544	-0.022659318	normal	0.954815695	-0.222626181	normal	0.926977546	0.027034107	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16765|0|hsa:84131|CEP78, C9orf81, IP63; centrosomal protein 78kDa; K16765 centrosomal protein CEP78 (A)"	--	[S]	Function unknown	Leucine Rich repeat	Centrosomal protein of 78 kDa GN=CEP78 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centrosomal protein of 78 kDa isoform X1 [Panthera tigris altaica]
ENSG00000148053(NTRK2)	--	0.016848421	2	0.042443972	5	0.028191015	1	0.023494527	3	0.008176206	0	0.016709684	2	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04360|0|ptr:735394|NTRK2; neurotrophic tyrosine kinase, receptor, type 2; K04360 neurotrophic tyrosine kinase receptor type 2 [EC:2.7.10.1] (A)"	MAPK signaling pathway (ko04010);; Neurotrophin signaling pathway (ko04722);; Alcoholism (ko05034)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Leucine rich repeat;; Leucine rich repeat N-terminal domain;; Immunoglobulin domain	BDNF/NT-3 growth factors receptor (Precursor) GN=NTRK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: BDNF/NT-3 growth factors receptor isoformX2 [Canis lupus familiaris]
ENSG00000148057(IDNK)	--	4.217538905	64	2.600619277	41	6.420554	78	4.803085115	59	4.295885	58	3.163130457	44	0.973705385	-0.144572994	normal	0.940824566	0.464534455	normal	0.530313106	-0.812996554	normal	0.766865679	-0.205934006	normal	[G]	Carbohydrate transport and metabolism	--	--	--	[G]	Carbohydrate transport and metabolism	Shikimate kinase;; AAA domain;; AAA domain	Probable gluconokinase GN=IDNK OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: probable gluconokinase isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000148082(SHC3)	--	1.317420403	123	1.3843125	106	1.258583862	125	2.000649983	255	1.754720463	236	1.970667596	208	0.000537505	1.012045853	up	0.000113047	1.122292932	up	0.128645563	0.719545379	normal	0.000272472	0.959941155	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17448|0|hsa:53358|SHC3, N-Shc, NSHC, RAI, SHCC; SHC (Src homology 2 domain containing) transforming protein 3; K17448 SHC- transforming protein 3 (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Alcoholism (ko05034);; Bacterial invasion of epithelial cells (ko05100);; Glioma (ko05214);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; SH2 domain	SHC-transforming protein 3 GN=SHC3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SHC-transforming protein 3 [Ochotona princeps]
ENSG00000148090(AUH)	--	12.52872552	262	12.43645526	258	12.46117724	289	7.984136523	183	10.92900728	215	9.54605819	216	0.46008278	-0.544710676	normal	0.915183581	-0.282643244	normal	0.749855686	-0.425743318	normal	0.122570504	-0.418359773	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	K05607|0|hsa:549|AUH; AU RNA binding protein/enoyl-CoA hydratase (EC:4.2.1.18); K05607 methylglutaconyl-CoA hydratase [EC:4.2.1.18] (A)	"Valine, leucine and isoleucine degradation (ko00280)"	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family	"Methylglutaconyl-CoA hydratase, mitochondrial (Precursor) GN=AUH OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: methylglutaconyl-CoA hydratase, mitochondrial [Leptonychotes weddellii]"
ENSG00000148110(MFSD14B)	--	52.13320623	2567	52.55050616	2613	48.79930704	2403	50.3066077	2492	42.65130558	2090	41.81572569	2067	0.987652238	-0.073566798	normal	0.892109488	-0.343407991	normal	0.967160591	-0.225436575	normal	0.238320253	-0.211580738	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Major Facilitator Superfamily	Hippocampus abundant transcript-like protein 1 GN=HIATL1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: hippocampus abundant transcript-like protein 1-like [Ceratotherium simum simum]
ENSG00000148120(C9orf3)	--	77.50963365	1769	95.45261418	2142	79.78099116	1831	56.23806781	1464	71.40548955	1688	70.88295112	1634	0.915107768	-0.303560413	normal	0.847146431	-0.364779254	normal	0.974380436	-0.172364461	normal	0.086448266	-0.283705889	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	"K09606|0|hsa:84909|C9orf3, AOPEP, AP-O, APO, C90RF3, ONPEP; chromosome 9 open reading frame 3; K09606 aminopeptidase O [EC:3.4.11.-] (A)"	--	[IOVE]	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms;; Amino acid transport and metabolism"	"Peptidase family M1;; Leukotriene A4 hydrolase, C-terminal;; Peptidase MA superfamily"	Aminopeptidase O GN=AOPEP OS=Homo sapiens (Human) PE=1 SV=2	EIOV	"Amino acid transport and metabolism;; Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms"	PREDICTED: aminopeptidase O isoform 1 [Odobenus rosmarus divergens]
ENSG00000148123(PLPPR1)	--	0	0	0	0	0.0784096	2	0.0262635	1	0.028888207	0	0.052206358	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	PAP2 superfamily	Lipid phosphate phosphatase-related protein type 1 GN=LPPR1 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: lipid phosphate phosphatase-related protein type 1-like isoformX1 [Sus scrofa]
ENSG00000148136(OR13C4)	--	0	0	0	0	0	0	0	0	0	0	0.207694	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:138804|OR13C4, HSHTPCRX17, HTPCRX17, OR2K1, OR37F, OR9-7; olfactory receptor, family 13, subfamily C, member 4; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 13C4 GN=OR13C4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: olfactory receptor 13C4-like [Galeopterus variegatus]
ENSG00000148143(ZNF462)	--	5.57429731	970	5.829102796	997	5.826281334	979	7.47506365	1104	4.295129182	882	6.55875125	905	0.968998536	0.155620099	normal	0.957631784	-0.197921977	normal	0.972617565	-0.121487266	normal	0.865024612	-0.049081771	normal	--	--	--	--	--	[R]	General function prediction only	C2H2-type zinc-finger domain	Zinc finger protein 462 GN=ZNF462 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 462 isoform X3 [Tupaia chinensis]
ENSG00000148153(INIP)	--	9.10196	471	11.574315	567	11.471843	583	10.413149	566	9.788874017	561	10.875402	605	0.935415609	0.233547014	normal	0.971765208	-0.036676179	normal	0.97276875	0.045033141	normal	0.805447386	0.074730236	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: DNA repair (GO:0006281);; Biological Process: cellular response to DNA damage stimulus (GO:0006974);; Cellular Component: SOSS complex (GO:0070876);; 	--	--	--	--	--	SOSS complex subunit C GN=INIP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	chromosome 9 open reading frame 80 ortholog [Sus scrofa] 
ENSG00000148154(UGCG)	--	19.0609	994	21.3142	1121	24.2277	1253	15.606	825	9.66329	505	17.3531	908	0.900054491	-0.299175502	normal	5.44E-09	-1.169442199	down	0.449804011	-0.472241118	normal	0.03125404	-0.610479967	normal	[M]	Cell wall/membrane/envelope biogenesis	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	K00720|0|ptr:464660|UGCG; UDP-glucose ceramide glucosyltransferase; K00720 ceramide glucosyltransferase [EC:2.4.1.80] (A)	Sphingolipid metabolism (ko00600)	[IM]	Lipid transport and metabolism;; Cell wall/membrane/envelope biogenesis	Glycosyl transferase family 21;; Glycosyltransferase like family 2;; Glycosyl transferase family group 2;; Glycosyl transferase family 2	Ceramide glucosyltransferase GN=UGCG OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	ceramide glucosyltransferase [Canis lupus familiaris]
ENSG00000148156(ACTL7B)	--	0.0238976	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Actin	Actin-like protein 7B GN=ACTL7B OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	actin-like protein 7B [Bos taurus] 
ENSG00000148158(SNX30)	--	3.49640476	459	4.71082053	475	3.798490962	514	4.902357	671	5.89701349	758	6.391983	822	0.320968173	0.515551472	normal	0.037511343	0.651188659	normal	0.021000273	0.667511693	normal	0.00027013	0.616109602	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17921|0|pon:100436039|SNX30; sorting nexin family member 30; K17921 sorting nexin-7/30 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain;; Vps5 C terminal like;; BAR domain	Sorting nexin-30 GN=SNX30 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-30 [Chrysochloris asiatica]
ENSG00000148175(STOM)	--	93.8374	3194	109.0893	3635	105.4694	3357	107.6006	3592	83.5671	2674	223.98225	7403	0.986850167	0.138527914	normal	0.58993478	-0.464156343	normal	7.17E-10	1.132293677	up	0.681723093	0.405323476	normal	--	--	--	K17286|0|pps:100989240|STOM; stomatin; K17286 erythrocyte band 7 integral membrane protein (A)	--	[C]	Energy production and conversion	SPFH domain / Band 7 family	Erythrocyte band 7 integral membrane protein GN=STOM OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: erythrocyte band 7 integral membrane protein isoform X1 [Equus caballus] 
ENSG00000148180(GSN)	--	47.29221934	2524	40.45567956	2170	45.36406401	2212	35.16426826	1907	45.984026	2481	29.18012126	1630	0.648893616	-0.434933593	normal	0.978672678	0.171688171	normal	0.58126413	-0.448412296	normal	0.461074641	-0.22006864	normal	--	--	--	"K05768|0|hsa:2934|GSN, ADF, AGEL; gelsolin; K05768 gelsolin (A)"	Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Viral carcinogenesis (ko05203)	[Z]	Cytoskeleton	Gelsolin repeat	Gelsolin (Precursor) GN=GSN OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: gelsolin isoform X1 [Panthera tigris altaica]
ENSG00000148187(MRRF)	--	27.98719057	823	30.73628563	828	28.75225015	786	28.50388109	872	31.61377973	960	33.65331096	933	0.976507882	0.052508206	normal	0.958440071	0.191651765	normal	0.94096978	0.238634427	normal	0.457997625	0.16113361	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02838|0|pon:100436808|MRRF; mitochondrial ribosome recycling factor; K02838 ribosome recycling factor (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Ribosome recycling factor	"Ribosome-recycling factor, mitochondrial (Precursor) GN=MRRF OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: ribosome-recycling factor, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000148200(NR6A1)	--	2.07796093	226	1.52277256	194	2.088079492	189	1.175267631	128	1.062961819	126	0.840015501	82	0.016338765	-0.843284745	normal	0.333003121	-0.637839632	normal	9.94E-05	-1.198007114	down	0.001781569	-0.8804797	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08561|0|ptr:464725|NR6A1, NR5A1; nuclear receptor subfamily 6, group A, member 1; K08561 germ cell nuclear factor (A)"	--	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor subfamily 6 group A member 1 GN=NR6A1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor subfamily 6 group A member 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000148204(CRB2)	--	0.0209418	2	0.111363	11	0.099306735	9	0.010451518	1	0.0101878	0	0.0207756	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K16681|0|hsa:286204|CRB2; crumbs family member 2; K16681 protein crumbs (A)	Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	EGF-like domain;; Laminin G domain;; Calcium-binding EGF domain;; Laminin G domain;; Human growth factor-like EGF	Protein crumbs homolog 2 (Precursor) GN=CRB2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein crumbs homolog 2 [Sus scrofa]
ENSG00000148218(ALAD)	--	8.385004626	543	7.24955	462	8.294499183	510	7.188333	454	8.982878	545	6.811419683	421	0.901501889	-0.288198882	normal	0.941924795	0.216284388	normal	0.905212365	-0.284039944	normal	0.688522978	-0.114651184	normal	[H]	Coenzyme transport and metabolism	Molecular Function: porphobilinogen synthase activity (GO:0004655);; Biological Process: tetrapyrrole biosynthetic process (GO:0033014);; Molecular Function: metal ion binding (GO:0046872);; 	"K01698|0|hsa:210|ALAD, ALADH, PBGS; aminolevulinate dehydratase (EC:4.2.1.24); K01698 porphobilinogen synthase [EC:4.2.1.24] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	Delta-aminolevulinic acid dehydratase	Delta-aminolevulinic acid dehydratase GN=ALAD OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: delta-aminolevulinic acid dehydratase isoform X1 [Tupaia chinensis] 
ENSG00000148219(ASTN2)	--	6.946624419	489	6.2163983	450	6.872815579	537	4.2588195	398	3.036451702	354	4.640168002	426	0.864293645	-0.32675789	normal	0.814829857	-0.366210927	normal	0.844834309	-0.341278511	normal	0.110188132	-0.346131204	normal	--	--	--	--	--	--	--	Coagulation Factor Xa inhibitory site;; MAC/Perforin domain	Astrotactin-2 (Precursor) GN=ASTN2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: astrotactin-2 isoform 1 [Trichechus manatus latirostris]
ENSG00000148225(WDR31)	--	2.376350241	265	2.092541306	223	2.027216568	217	2.125300842	233	2.292790546	246	1.93852755	209	0.942549158	-0.215163076	normal	0.959797202	0.119416802	normal	0.965507797	-0.062042931	normal	0.902065235	-0.056832889	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	"WD domain, G-beta repeat;; Nucleoporin Nup120/160"	WD repeat-containing protein 31 GN=WDR31 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: WD repeat-containing protein 31 [Galeopterus variegatus]
ENSG00000148229(POLE3)	--	42.46782	1515	45.2971	1644	43.05168	1530	53.36948	1920	52.21025	1852	42.49602	1516	0.910762149	0.310675845	normal	0.977447823	0.150316908	normal	0.984096369	-0.021531961	normal	0.445506324	0.151520694	normal	[B]	Chromatin structure and dynamics	--	"K02326|8.77742e-62|ptr:741748|POLE3; polymerase (DNA directed), epsilon 3, accessory subunit (EC:2.7.7.7); K02326 DNA polymerase epsilon subunit 3 [EC:2.7.7.7] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; HTLV-I infection (ko05166)	[K]	Transcription	Histone-like transcription factor (CBF/NF-Y) and archaeal histone	DNA polymerase epsilon subunit 3 GN=POLE3 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase epsilon subunit 3 [Trichechus manatus latirostris]
ENSG00000148248(SURF4)	--	133.885999	6292	127.6872678	6084	131.2992729	6228	148.8555204	7042	147.4614458	6900	145.078388	6845	0.992512452	0.131603907	normal	0.990702821	0.160112261	normal	0.992504651	0.127960507	normal	0.524923862	0.138812732	normal	[S]	Function unknown	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SURF4 family	Surfeit locus protein 4 GN=SURF4 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	surfeit locus protein 4 [Bos taurus] 
ENSG00000148288(GBGT1)	--	0.146977749	5	0.13791417	5	0.111577075	3	1.517682067	42	1.329874498	40	0.764820593	25	9.03E-05	2.708978803	up	0.000201468	2.653755255	up	0.027886096	2.548065078	normal	1.35E-06	3.017650644	up	--	--	"Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00722|0|ggo:101145846|GBGT1; globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 isoform 1; K00722 globoside alpha-N-acetylgalactosaminyltransferase [EC:2.4.1.88] (A)"	Glycosphingolipid biosynthesis - globo series (ko00603)	--	--	Glycosyltransferase family 6	"Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 GN=GBGT1 OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 isoform X1 [Galeopterus variegatus] "
ENSG00000148290(SURF1)	--	20.27208999	402	18.75670432	384	17.894753	363	21.91963344	446	23.690853	466	23.982766	478	0.963309356	0.118585542	normal	0.922430503	0.25687756	normal	0.77118325	0.387339168	normal	0.293460715	0.253606517	normal	[S]	Function unknown	Cellular Component: membrane (GO:0016020);; 	K14998|0|ptr:746511|SURF1; surfeit 1; K14998 surfeit locus 1 family protein (A)	--	[C]	Energy production and conversion	SURF1 family	Surfeit locus protein 1 GN=SURF1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: surfeit locus protein 1 isoform X2 [Canis lupus familiaris]
ENSG00000148291(SURF2)	--	13.3544	176	13.5899	187	12.3559	173	14.7483	207	17.782	235	16.911	229	0.94901347	0.201599015	normal	0.905909935	0.305984457	normal	0.833634767	0.393286715	normal	0.353875153	0.30313547	normal	--	--	--	--	--	--	--	Surfeit locus protein 2 (SURF2)	Surfeit locus protein 2 GN=SURF2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: surfeit locus protein 2 [Ceratotherium simum simum]
ENSG00000148296(SURF6)	--	24.53381653	1890	22.26419031	1791	23.88395033	1912	27.22237831	2077	28.22022931	2075	24.33360236	1856	0.983596537	0.105201122	normal	0.972608667	0.190769683	normal	0.985620129	-0.051136201	normal	0.724935669	0.08184744	normal	--	--	--	--	--	[S]	Function unknown	Surfeit locus protein 6	Surfeit locus protein 6 GN=SURF6 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: surfeit locus protein 6 [Orcinus orca]
ENSG00000148300(REXO4)	--	16.63579908	834	16.65813304	857	16.29353444	833	21.89953986	1112	19.75059277	991	18.86900916	947	0.763389502	0.383591454	normal	0.960013415	0.187854817	normal	0.962526463	0.176455851	normal	0.174410704	0.251365601	normal	[L]	"Replication, recombination and repair"	--	"K18327|0|pps:100981569|REXO4; REX4, RNA exonuclease 4 homolog (S. cerevisiae); K18327 RNA exonuclease 4 [EC:3.1.-.-] (A)"	--	[L]	"Replication, recombination and repair"	Exonuclease	RNA exonuclease 4 GN=REXO4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: RNA exonuclease 4 [Galeopterus variegatus]
ENSG00000148303(RPL7A)	--	1547.901157	23480	1410.041122	21668	1428.379876	22004	1541.116035	23985	1584.483514	23829	1488.26096	22749	0.998204807	-0.000132224	normal	0.997398265	0.115718152	normal	0.998019071	0.039743192	normal	0.875136822	0.050117584	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02936|2.9173e-162|rno:296596|Rpl7a; ribosomal protein L7a; K02936 large subunit ribosomal protein L7Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	60S ribosomal protein L7a GN=RPL7A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L7a [Panthera tigris altaica]
ENSG00000148308(GTF3C5)	--	24.60384602	1200	25.1470297	1225	25.92410338	1281	24.22545868	1196	26.91267264	1312	26.61842321	1308	0.981175231	-0.035603618	normal	0.979740557	0.077466995	normal	0.982357652	0.021775183	normal	0.949106958	0.021401199	normal	--	--	--	"K15202|0|hsa:9328|GTF3C5, TFIIIC63, TFIIICepsilon, TFiiiC2-63; general transcription factor IIIC, polypeptide 5, 63kDa; K15202 general transcription factor 3C polypeptide 5 (transcription factor C subunit 1) (A)"	--	[K]	Transcription	RNA polymerase III transcription factor (TF)IIIC subunit	General transcription factor 3C polypeptide 5 GN=GTF3C5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: general transcription factor 3C polypeptide 5 isoform 1 [Ceratotherium simum simum]
ENSG00000148331(ASB6)	--	9.74013342	803	8.817170314	771	8.001948324	698	8.481013213	739	10.17022249	870	7.95100113	702	0.965455151	-0.150357871	normal	0.965570005	0.152576128	normal	0.975490187	-4.73E-05	normal	0.996330974	0.003118256	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10328|0|ptr:742408|ASB6; ankyrin repeat and SOCS box containing 6; K10328 ankyrin repeat and SOCS box protein 6 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SOCS box	Ankyrin repeat and SOCS box protein 6 GN=ASB6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 6 isoform X1 [Camelus ferus] 
ENSG00000148334(PTGES2)	--	39.64839583	1777	40.82964504	1775	38.98938682	1712	35.550529	1533	38.889413	1678	37.8978432	1795	0.953842648	-0.243691134	normal	0.981879508	-0.102413108	normal	0.984611565	0.059957972	normal	0.679827713	-0.093266953	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Biological Process: cell redox homeostasis (GO:0045454);; 	K05309|0|ptr:464763|PTGES2; prostaglandin E synthase 2 (EC:5.3.99.3); K05309 microsomal prostaglandin-E synthase 2 [EC:5.3.99.3] (A)	Arachidonic acid metabolism (ko00590)	[R]	General function prediction only	"Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutaredoxin;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Prostaglandin E synthase 2 truncated form GN=PTGES2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: prostaglandin E synthase 2 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000148335(NTMT1)	--	23.757143	454	20.5310337	409	21.66262857	441	27.3694758	498	32.324488	557	22.1275451	408	0.966261967	0.102290594	normal	0.680876715	0.422805529	normal	0.963272957	-0.120072739	normal	0.597817075	0.144404337	normal	--	--	Biological Process: N-terminal protein amino acid methylation (GO:0006480);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: O-methyltransferase activity (GO:0008171);; 	K16219|1.31567e-164|nle:100603188|NTMT1; N-terminal Xaa-Pro-Lys N-methyltransferase 1; K16219 protein N-terminal methyltransferase [EC:2.1.1.244] (A)	--	[R]	General function prediction only	AdoMet dependent proline di-methyltransferase;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; O-methyltransferase	"N-terminal Xaa-Pro-Lys N-methyltransferase 1, N-terminally processed GN=NTMT1 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	PREDICTED: N-terminal Xaa-Pro-Lys N-methyltransferase 1 [Trichechus manatus latirostris]
ENSG00000148337(CIZ1)	--	28.43135455	2033	32.56358338	2307	31.96719769	2289	35.805973	2337	36.4833104	2514	37.6513961	2661	0.97819572	0.170095292	normal	0.985541097	0.102475726	normal	0.973263991	0.208831531	normal	0.413547487	0.159689885	normal	--	--	--	--	--	--	--	Zinc-finger double-stranded RNA-binding	Cip1-interacting zinc finger protein GN=CIZ1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cip1-interacting zinc finger protein isoform X1 [Lipotes vexillifer]
ENSG00000148339(SLC25A25)	--	5.3274016	355	5.543285295	379	5.282136004	346	4.998334722	335	4.625713116	297	5.506555	341	0.962442906	-0.113982249	normal	0.815962468	-0.371482429	normal	0.968296394	-0.029163342	normal	0.565054313	-0.171828943	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K14684|0|mcf:102140697|SLC25A25; solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25; K14684 solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41 (A)"	--	[F]	Nucleotide transport and metabolism	Mitochondrial carrier protein;; EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Cytoskeletal-regulatory complex EF hand	Calcium-binding mitochondrial carrier protein SCaMC-2 GN=UNQ549/PRO1106 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: calcium-binding mitochondrial carrier protein SCaMC-2 isoform X1 [Elephantulus edwardii]
ENSG00000148341(SH3GLB2)	--	23.88778869	1080	17.35135063	825	20.31378729	1017	19.36000354	856	20.86214046	960	17.31998084	782	0.804237396	-0.36559512	normal	0.956968466	0.19687892	normal	0.754445294	-0.386712864	normal	0.400812258	-0.190745918	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	K11248|0|ptr:464781|SH3GLB2; SH3-domain GRB2-like endophilin B2; K11248 endophilin-B (A)	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	BAR domain;; Variant SH3 domain;; Bin/amphiphysin/Rvs domain for vesicular trafficking;; Variant SH3 domain;; SH3 domain	Endophilin-B2 GN=SH3GLB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endophilin-B2 isoform X1 [Condylura cristata]
ENSG00000148343(MIGA2)	--	4.274033866	330	4.7164379	371	5.123057	404	6.312948	473	6.634824883	460	6.120479	472	0.486908721	0.486640468	normal	0.902728224	0.287733082	normal	0.941773542	0.215393492	normal	0.149736175	0.325555979	normal	--	--	Biological Process: mitochondrial fusion (GO:0008053);; 	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2217)	Protein FAM73B GN=FAM73B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM73B [Bubalus bubalis]
ENSG00000148344(PTGES)	--	140.615726	3995	110.4852765	3182	122.2551	3526	169.29256	4820	178.78303	5001	186.57832	5283	0.976349244	0.239921281	normal	0.043199749	0.630615243	normal	0.128917957	0.574830743	normal	0.001534513	0.47602332	normal	--	--	--	"K15729|3.10033e-108|hsa:9536|PTGES, MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1; prostaglandin E synthase (EC:5.3.99.3); K15729 microsomal prostaglandin-E synthase 1 [EC:5.3.99.3] (A)"	Arachidonic acid metabolism (ko00590)	--	--	MAPEG family	Prostaglandin E synthase GN=PTGES OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: prostaglandin E synthase [Orycteropus afer afer]
ENSG00000148346(LCN2)	--	1.623893033	17	2.567081647	27	0.92132298	9	30.4927861	336	35.54071152	377	65.99934036	716	0	4.157120489	up	0	3.709868893	up	0	6.085168664	up	8.43E-07	4.732530297	up	--	--	--	--	--	--	--	Lipocalin / cytosolic fatty-acid binding protein family	Neutrophil gelatinase-associated lipocalin (Precursor) GN=LCN2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: neutrophil gelatinase-associated lipocalin [Camelus dromedarius]
ENSG00000148356(LRSAM1)	--	9.264196944	677	6.761734335	503	8.056897744	600	6.964357182	509	8.277590041	600	7.892006984	580	0.59393713	-0.441163293	normal	0.936465751	0.23233729	normal	0.972149202	-0.05705477	normal	0.728258727	-0.096366436	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10641|0|hsa:90678|LRSAM1, CMT2P, RIFLE, TAL; leucine rich repeat and sterile alpha motif containing 1; K10641 E3 ubiquitin-protein ligase LRSAM1 [EC:6.3.2.19] (A)"	--	[R]	General function prediction only	"Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Zinc finger, C3HC4 type (RING finger);; Leucine rich repeat;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)"	E3 ubiquitin-protein ligase LRSAM1 GN=LRSAM1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: E3 ubiquitin-protein ligase LRSAM1 [Vicugna pacos]
ENSG00000148357(HMCN2)	--	0.00860437	3	0	0	0.011573405	0	0.07674914	2	0.0111465	3	0.07619845	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K17341|0|hsa:256158|HMCN2; hemicentin 2; K17341 hemicentin (A)	--	[RP]	General function prediction only;; Inorganic ion transport and metabolism	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Calcium-binding EGF domain;; G2F domain;; Penicillin-Binding Protein C-terminus Family;; Complement Clr-like EGF-like;; Immunoglobulin C1-set domain;; CD47 immunoglobulin-like domain;; Immunoglobulin C2-set domain;; Coagulation Factor Xa inhibitory site;; von Willebrand factor type A domain;; EGF-like domain;; Zona-pellucida-binding protein (Sp38);; Alphaherpesvirus glycoprotein I	Hemicentin-2 (Precursor) GN=HMCN2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: hemicentin-2 [Odobenus rosmarus divergens]
ENSG00000148358(GPR107)	--	25.48297045	3287	23.41225486	3055	24.36234784	3132	29.67385292	3846	30.01182762	3831	28.21605994	3577	0.981329498	0.195670426	normal	0.944813732	0.30498702	normal	0.982237807	0.183291594	normal	0.200653325	0.226997776	normal	--	--	Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: response to pheromone (GO:0019236);; 	--	--	[T]	Signal transduction mechanisms	Lung seven transmembrane receptor;; Rhodopsin-like GPCR transmembrane domain	Protein GPR107 (Precursor) GN=GPR107 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein GPR107 isoform X3 [Canis lupus familiaris]
ENSG00000148362(C9orf142)	--	28.60602	384	24.90737	338	30.64867	433	27.14637	385	25.64223	329	24.02661	332	0.969058703	-0.02697235	normal	0.96589777	-0.0600897	normal	0.772638504	-0.389915274	normal	0.575238441	-0.164341428	normal	--	--	Biological Process: double-strand break repair via nonhomologous end joining (GO:0006303);; 	--	--	--	--	Domain of unknown function (DUF4610)	Uncharacterized protein C9orf142 GN=C9orf142 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C9orf142 homolog [Galeopterus variegatus]
ENSG00000148377(IDI2)	--	2.56175	62	2.27041	56	2.62232	64	2.44194	60	3.26164	78	2.12857	52	0.975922975	-0.076217818	normal	0.920615372	0.446366501	normal	0.963081612	-0.299973901	normal	0.971095564	0.04083157	normal	[I]	Lipid transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K01823|6.95923e-145|hsa:91734|IDI2, IPPI2; isopentenyl-diphosphate delta isomerase 2 (EC:5.3.3.2); K01823 isopentenyl-diphosphate delta-isomerase [EC:5.3.3.2] (A)"	Terpenoid backbone biosynthesis (ko00900)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	NUDIX domain	Isopentenyl-diphosphate delta-isomerase 2 GN=IDI2 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: isopentenyl-diphosphate Delta-isomerase 2-like [Condylura cristata]
ENSG00000148384(INPP5E)	--	6.834994504	504	7.356489	544	7.98956	618	7.068603278	505	6.814590552	499	6.831644914	508	0.971481844	-0.02788768	normal	0.96066149	-0.145570694	normal	0.900743096	-0.290284975	normal	0.525184117	-0.160816214	normal	--	--	--	"K01099|0|hsa:56623|INPP5E, CORS1, CPD4, JBTS1, MORMS, PPI5PIV; inositol polyphosphate-5-phosphatase, 72 kDa (EC:3.1.3.36); K01099 phosphatidylinositol-bisphosphatase [EC:3.1.3.36] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endonuclease/Exonuclease/phosphatase family	72 kDa inositol polyphosphate 5-phosphatase (Precursor) GN=INPP5E OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: 72 kDa inositol polyphosphate 5-phosphatase isoform X1 [Equus caballus]
ENSG00000148396(SEC16A)	--	24.6756598	4105	24.04470232	4147	25.36650492	4368	25.15812119	4147	27.23139317	4798	25.80697656	4415	0.992319823	-0.016140428	normal	0.984875009	0.188874475	normal	0.992693619	0.007146678	normal	0.812661443	0.061366028	normal	--	--	--	--	--	[K]	Transcription	Sec23-binding domain of Sec16;; Vesicle coat trafficking protein Sec16 mid-region	Protein transport protein Sec16A GN=SEC16A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec16A isoform 1 [Ceratotherium simum simum]
ENSG00000148399(DPH7)	--	7.825662943	363	7.92980316	389	9.331677261	427	9.67569043	420	9.172927539	397	8.536198092	387	0.951832815	0.178883193	normal	0.968726763	0.007911848	normal	0.958402029	-0.14963702	normal	0.986272296	0.009046148	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17868|0|hsa:92715|DPH7, C9orf112, RRT2, WDR85; diphthamide biosynthesis 7; K17868 diphthamide biosynthesis protein 7 (A)"	--	[E]	Amino acid transport and metabolism	"WD domain, G-beta repeat"	Diphthamide biosynthesis protein 7 GN=DPH7 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	hypothetical protein PANDA_015786 [Ailuropoda melanoleuca]
ENSG00000148400(NOTCH1)	--	3.168523131	622	2.4045543	477	3.23252668	652	5.108600245	1002	4.245035627	837	3.959356631	787	0.022393325	0.655776514	normal	0.001554715	0.787902572	normal	0.924345101	0.262644977	normal	0.004113894	0.563086326	normal	[R]	General function prediction only	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: cell differentiation (GO:0030154);; 	"K02599|0|hsa:4851|NOTCH1, AOS5, AOVD1, TAN1, hN1; notch 1; K02599 Notch (A)"	Dorso-ventral axis formation (ko04320);; Notch signaling pathway (ko04330);; Thyroid hormone signaling pathway (ko04919);; Prion diseases (ko05020);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	EGF-like domain;; Ankyrin repeats (3 copies);; Calcium-binding EGF domain;; Ankyrin repeat;; Human growth factor-like EGF;; EGF-like domain;; LNR domain;; NOTCH protein;; Domain of unknown function (DUF3454);; Ankyrin repeats (many copies);; NOTCH protein;; Ankyrin repeat;; Ankyrin repeats (many copies)	Notch 1 intracellular domain (Precursor) GN=NOTCH1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: neurogenic locus notch homolog protein 1 [Ceratotherium simum simum]
ENSG00000148408(CACNA1B)	--	0.051029422	10	0.045987598	8	0.066120707	12	0.005099341	1	0.02990096	5	0.013706917	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04849|0|hsa:774|CACNA1B, BIII, CACNL1A5, CACNN, Cav2.2; calcium channel, voltage-dependent, N type, alpha 1B subunit; K04849 voltage-dependent calcium channel N type alpha-1B (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; Synaptic vesicle cycle (ko04721);; Retrograde endocannabinoid signaling (ko04723);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Taste transduction (ko04742);; Type II diabetes mellitus (ko04930);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Voltage gated calcium channel IQ domain;; Polycystin cation channel	Voltage-dependent N-type calcium channel subunit alpha-1B GN=CACNA1B OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	voltage-dependent N-type calcium channel subunit alpha-1B [Bos taurus] 
ENSG00000148411(NACC2)	--	19.64640973	2452	19.33452497	2467	20.43560867	2611	26.55707957	3320	27.18474795	3395	22.60716214	2844	0.774862404	0.406172559	normal	0.68443682	0.438997022	normal	0.986319512	0.114963748	normal	0.043442597	0.322724408	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10486|0|hsa:138151|NACC2, BEND9, BTBD14, BTBD14A, BTBD31, NAC-2, RBB; NACC family member 2, BEN and BTB (POZ) domain containing; K10486 BTB/POZ domain-containing protein 14 (A)"	--	[R]	General function prediction only	BTB/POZ domain;; BEN domain	Nucleus accumbens-associated protein 2 GN=NACC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nucleus accumbens-associated protein 2 [Galeopterus variegatus]
ENSG00000148426(PROSER2)	--	9.768717588	366	9.175750926	358	13.91866106	476	17.67032257	747	12.27199951	523	14.08589418	545	5.48E-06	0.995449	normal	0.350378694	0.523584882	normal	0.952202892	0.186449234	normal	0.050859862	0.575143088	normal	--	--	--	--	--	--	--	Specifically androgen-regulated gene protein	Proline and serine-rich protein 2 GN=PROSER2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: proline and serine-rich protein 2 [Ceratotherium simum simum]
ENSG00000148429(USP6NL)	--	9.136945039	748	9.84688727	742	8.78629895	727	9.597983299	760	7.810094076	666	9.345321594	734	0.976228653	-0.007855109	normal	0.958245622	-0.176942687	normal	0.975967012	0.005521825	normal	0.840002795	-0.058970251	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	USP6 N-terminal-like protein GN=USP6NL OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: USP6 N-terminal-like protein isoform X1 [Tupaia chinensis]
ENSG00000148444(COMMD3)	--	48.49417	1510	45.80718518	1439	52.35474307	1608	55.943812	1798	53.28845892	1646	60.67326	1918	0.962111481	0.220806119	normal	0.972248895	0.172301781	normal	0.954628494	0.245831924	normal	0.234686975	0.213815488	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 3 GN=COMMD3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COMM domain-containing protein 3 [Ailuropoda melanoleuca] 
ENSG00000148450(MSRB2)	--	10.44276093	235	5.9402041	209	11.97233008	267	10.63813342	223	10.54584349	270	8.367719368	244	0.962366931	-0.105739487	normal	0.869387133	0.345823115	normal	0.958703571	-0.137435435	normal	0.955474803	0.03132846	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: peptide-methionine (R)-S-oxide reductase activity (GO:0033743);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07305|4.18583e-101|hsa:22921|MSRB2, CBS-1, CBS1, MSRB, PILB; methionine sulfoxide reductase B2; K07305 peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SelR domain	"Methionine-R-sulfoxide reductase B2, mitochondrial (Precursor) GN=MSRB2 OS=Homo sapiens (Human) PE=2 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: methionine-R-sulfoxide reductase B2, mitochondrial isoform X2 [Canis lupus familiaris]"
ENSG00000148459(PDSS1)	--	5.31633	147	4.84754	134	5.00471	138	7.62159	213	7.24555	200	5.85773	163	0.666401525	0.499843297	normal	0.563498382	0.551217529	normal	0.946874086	0.229594756	normal	0.176543626	0.437156695	normal	[H]	Coenzyme transport and metabolism	Biological Process: isoprenoid biosynthetic process (GO:0008299);; 	"K12504|0|hsa:23590|PDSS1, COQ1, COQ10D2, DPS, SPS, TPRT, TPT, TPT_1, hDPS1; prenyl (decaprenyl) diphosphate synthase, subunit 1 (EC:2.5.1.91); K12504 decaprenyl-diphosphate synthase subunit 1 [EC:2.5.1.91] (A)"	Terpenoid backbone biosynthesis (ko00900)	[H]	Coenzyme transport and metabolism	Polyprenyl synthetase	Decaprenyl-diphosphate synthase subunit 1 GN=PDSS1 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: decaprenyl-diphosphate synthase subunit 1 [Trichechus manatus latirostris]
ENSG00000148468(FAM171A1)	--	20.496413	1083	21.3365586	1020	20.90967612	1098	19.42354932	1012	20.22742602	1064	11.740346	649	0.973171534	-0.128467619	normal	0.979000021	0.03944518	normal	0.001409225	-0.765491615	normal	0.394822885	-0.254454192	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0560	Protein FAM171A1 (Precursor) GN=FAM171A1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM171A1 [Orycteropus afer afer]
ENSG00000148481(MINDY3)	--	11.30851438	379	10.854536	363	13.0133059	416	10.76254019	363	9.486796279	301	10.919761	365	0.965119176	-0.092676614	normal	0.903158201	-0.290302258	normal	0.947396064	-0.19621641	normal	0.496045113	-0.19143309	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF4205)	Protein FAM188A GN=FAM188A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM188A-like [Tupaia chinensis]
ENSG00000148483(TMEM236)	--	0.076661953	6	0.0255542	2	0.0766417	5	0.164259226	13	0.037018372	2	0.189691824	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 236 GN=TMEM236 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	transmembrane protein 236 [Oryctolagus cuniculus]
ENSG00000148484(RSU1)	--	53.42752932	1742	56.98396758	1935	56.076983	1781	65.792004	2336	66.28961147	2223	61.775243	2096	0.782656615	0.392163784	normal	0.975960165	0.178617503	normal	0.963844768	0.226482304	normal	0.116468859	0.264473836	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Ras suppressor protein 1 GN=RSU1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	Cubilin [Myotis davidii]
ENSG00000148488(ST8SIA6)	--	0	0	0	0	0	0	0.140862719	3	0.055662121	1	0.0569952	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K06615|0|hsa:338596|ST8SIA6, SIA8F, SIAT8F, ST8SIA-VI; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 (EC:2.4.99.-); K06615 alpha-N-acetyl-neuraminate alpha-2,8-sialyltransferase (sialyltransferase 8F) [EC:2.4.99.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-2,8-sialyltransferase 8F GN=ST8SIA6 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-2,8-sialyltransferase 8F [Tupaia chinensis]"
ENSG00000148498(PARD3)	--	33.36463668	2753	31.15705485	2648	31.10957434	2599	62.99427951	5068	90.24002554	6838	87.9569957	6806	5.21E-05	0.849225282	normal	7.05E-14	1.34674856	up	4.00E-15	1.380043716	up	4.31E-08	1.205570446	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04237|0|hsa:56288|PARD3, ASIP, Baz, PAR3, PAR3alpha, PARD-3, PARD3A, PPP1R118, SE2-5L16, SE2-5LT1, SE2-5T2; par-3 family cell polarity regulator; K04237 partitioning defective protein 3 (A)"	Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Neuroactive ligand-receptor interaction (ko04080);; Endocytosis (ko04144);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Tight junction (ko04530)	[S]	Function unknown	Domain of unknown function (DUF3534);; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Partitioning defective 3 homolog GN=PARD3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: partitioning defective 3 homolog isoform X1 [Orycteropus afer afer]
ENSG00000148513(ANKRD30A)	--	0.039938688	2	0	0	0.020263339	0	0.91380083	61	1.270353617	79	1.33264802	84	3.65E-11	4.120571617	up	0	5.723929865	up	0	5.817259921	up	2.06E-21	6.785101259	up	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 30A GN=ANKRD30A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26 isoform X3 [Loxodonta africana]
ENSG00000148516(ZEB1)	--	8.051208172	685	7.740497856	700	8.315157365	738	7.767070657	679	5.848891984	567	6.038664572	487	0.974299673	-0.043426842	normal	0.867545682	-0.324651807	normal	0.077737987	-0.606449398	normal	0.106347544	-0.314936389	normal	[R]	General function prediction only	Molecular Function: DNA binding (GO:0003677);; 	"K09299|0|hsa:6935|ZEB1, AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A; zinc finger E-box binding homeobox 1; K09299 zinc finger homeobox protein 1/2 (A)"	Transcriptional misregulation in cancer (ko05202);; MicroRNAs in cancer (ko05206)	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; Drought induced 19 protein (Di19), zinc-binding;; C2H2-type zinc finger;; Homeobox domain"	Zinc finger E-box-binding homeobox 1 GN=ZEB1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger E-box-binding homeobox 1 isoform X1 [Orycteropus afer afer]
ENSG00000148541(FAM13C)	--	0.186422807	12	0.242189609	13	0.073038476	3	0.129147081	7	0.162113541	9	0.12816228	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM13C GN=FAM13C OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM13C isoform X1 [Ursus maritimus]
ENSG00000148572(NRBF2)	--	12.451066	438	11.76440618	415	9.674592896	339	14.87189	526	16.096431	564	14.201336	501	0.935259787	0.232554476	normal	0.688083677	0.419840301	normal	0.246789638	0.553191459	normal	0.053660268	0.394886477	normal	--	--	Biological Process: autophagy (GO:0006914);; 	--	--	--	--	Domain of unknown function (DUF1875)	Nuclear receptor-binding factor 2 GN=NRBF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor-binding factor 2 isoform X1 [Bison bison bison]
ENSG00000148584(A1CF)	--	0.095799414	5	0.02715182	4	0.034005216	4	0.167028438	22	0.176681371	25	0.233198116	26	0.519431993	1.822114655	normal	0.084883393	2.248064079	normal	0.051511169	2.312427065	normal	0.000276398	2.468564859	up	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; double strand RNA binding domain from DEAD END PROTEIN 1;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	APOBEC1 complementation factor GN=A1CF OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: APOBEC1 complementation factor isoform X1 [Physeter catodon]
ENSG00000148600(CDHR1)	--	0.122399581	10	0.155524267	14	0.128425518	16	0.052130004	5	0.081790877	6	0.2184489	20	--	--	--	--	--	--	0.987663316	0.289151398	normal	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16501|0|ptr:450564|CDHR1, PCDH21; cadherin-related family member 1; K16501 cadherin-related family member 1 (A)"	--	[S]	Function unknown	Cadherin domain	Cadherin-related family member 1 (Precursor) GN=CDHR1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cadherin-related family member 1 [Oryctolagus cuniculus]
ENSG00000148602(LRIT1)	--	0	0	0	0	0	0	0.0253514	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Leucine Rich Repeat;; Leucine rich repeat	"Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 (Precursor) GN=LRIT1 OS=Homo sapiens (Human) PE=2 SV=1"	T	Signal transduction mechanisms	"Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 1 [Pteropus alecto]"
ENSG00000148606(POLR3A)	--	7.267779629	1035	7.591427539	1087	8.266225536	1177	8.31004351	1186	8.254087928	1171	7.400371962	1057	0.96832208	0.165411473	normal	0.977765143	0.085847492	normal	0.968956842	-0.163208983	normal	0.925031587	0.028103825	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	"K03018|0|hsa:11128|POLR3A, ADDH, HLD7, RPC1, RPC155, hRPC155; polymerase (RNA) III (DNA directed) polypeptide A, 155kDa (EC:2.7.7.6); K03018 DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	"RNA polymerase Rpb1, domain 1;; RNA polymerase Rpb1, domain 5;; RNA polymerase Rpb1, domain 2;; RNA polymerase Rpb1, domain 3;; RNA polymerase Rpb1, domain 4"	DNA-directed RNA polymerase III subunit RPC1 GN=POLR3A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC1 [Ceratotherium simum simum]
ENSG00000148634(HERC4)	--	24.2941136	1513	26.79653983	1706	31.6002356	1960	36.34815461	2328	22.49216493	1422	28.21907702	1737	0.072178089	0.590360138	normal	0.931335623	-0.283846702	normal	0.973649625	-0.182397749	normal	0.905060143	0.061345459	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	K10615|0|pon:100443303|HERC4; HECT and RLD domain containing E3 ubiquitin protein ligase 4; K10615 E3 ubiquitin-protein ligase HERC4 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Regulator of chromosome condensation (RCC1) repeat;; HECT-domain (ubiquitin-transferase);; Regulator of chromosome condensation (RCC1) repeat	Probable E3 ubiquitin-protein ligase HERC4 GN=HERC4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase HERC4 isoform X4 [Oryctolagus cuniculus]
ENSG00000148655(C10orf11)	--	7.46805049	51	9.419349757	40	7.985203311	61	12.4565028	88	17.54406112	123	11.273672	81	0.598690599	0.739039223	normal	1.40E-05	1.563771606	up	0.936362415	0.39235401	normal	0.02221769	0.921282763	normal	--	--	--	--	--	[A]	RNA processing and modification	Leucine-rich repeat;; Leucine Rich repeats (2 copies)	Leucine-rich repeat-containing protein C10orf11 GN=C10orf11 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: leucine-rich repeat-containing protein C10orf11 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000148660(CAMK2G)	--	15.17484676	1134	13.31720779	997	13.44638032	983	13.18629192	988	14.05125122	1047	12.02485161	903	0.949297976	-0.229336724	normal	0.978446389	0.049096801	normal	0.971504752	-0.130547253	normal	0.653278166	-0.105447283	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: calmodulin-dependent protein kinase activity (GO:0004683);; Molecular Function: calmodulin binding (GO:0005516);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04515|0|ecb:100064138|CAMK2G; calcium/calmodulin-dependent protein kinase II gamma; K04515 calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17] (A)	ErbB signaling pathway (ko04012);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; HIF-1 signaling pathway (ko04066);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Wnt signaling pathway (ko04310);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Gastric acid secretion (ko04971);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; Proteoglycans in cancer (ko05205);; Glioma (ko05214)	[T]	Signal transduction mechanisms	Protein kinase domain;; Calcium/calmodulin dependent protein kinase II Association;; Protein tyrosine kinase;; Domain of unknown function (DUF4440);; SnoaL-like domain	Calcium/calmodulin-dependent protein kinase type II subunit gamma GN=CAMK2G OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X2 [Erinaceus europaeus]
ENSG00000148671(ADIRF)	--	2.15298	29	1.15575	16	1.47595	20	0.431345	6	0.358948	4	0.290805	4	0.068062556	-2.045488047	normal	--	--	--	0.475613848	-1.97130074	normal	--	--	--	--	--	--	--	--	--	--	--	Adipogenesis regulatory factor GN=ADIRF OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: adipogenesis regulatory factor [Bubalus bubalis]
ENSG00000148672(GLUD1)	--	57.4507	2608	50.2103	2307	56.3022	2533	60.8982	2776	53.801	2443	48.5876	2225	0.988636843	0.05919763	normal	0.987175669	0.061170334	normal	0.975375388	-0.195208737	normal	0.94261681	-0.022569916	normal	[E]	Amino acid transport and metabolism	Biological Process: cellular amino acid metabolic process (GO:0006520);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00261|0|pon:100443755|GLUD1; glutamate dehydrogenase 1; K00261 glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] (A)	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; D-Glutamine and D-glutamate metabolism (ko00471);; Nitrogen metabolism (ko00910);; Proximal tubule bicarbonate reclamation (ko04964)"	[E]	Amino acid transport and metabolism	"Glutamate/Leucine/Phenylalanine/Valine dehydrogenase;; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain"	"Glutamate dehydrogenase 1, mitochondrial (Precursor) GN=GLUD1 OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: glutamate dehydrogenase 1, mitochondrial [Tupaia chinensis]"
ENSG00000148677(ANKRD1)	--	0.550098245	21	1.14411949	43	0.69512537	26	6.416681724	251	4.766596327	183	8.826659	341	0	3.456470612	up	1.41E-11	2.030466546	up	0	3.629962451	up	8.50E-08	3.085349641	up	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 1 GN=ANKRD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ankyrin repeat domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000148680(HTR7)	--	0.07592452	4	0	0	0	0	0	0	0.055572153	2	0.094634908	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04163|0|ptr:466154|HTR7; 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; K04163 5-hydroxytryptamine receptor 7 (A)"	Ras signaling pathway (ko04014);; Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Serotonergic synapse (ko04726)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	5-hydroxytryptamine receptor 7 GN=HTR7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: 5-hydroxytryptamine receptor 7 isoform X1 [Condylura cristata]
ENSG00000148688(RPP30)	--	25.65037178	414	29.87377	466	28.835866	448	28.26136916	450	26.01403367	421	28.72321	465	0.966628877	0.089144605	normal	0.954726387	-0.167364543	normal	0.970044915	0.045290472	normal	0.980122653	-0.012449896	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: ribonuclease activity (GO:0004540);; Biological Process: tRNA processing (GO:0008033);; 	"K03539|0|hsa:10556|RPP30, TSG15; ribonuclease P/MRP 30kDa subunit (EC:3.1.26.5); K03539 ribonuclease P/MRP protein subunit RPP1 [EC:3.1.26.5] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	RNase P subunit p30;; Putative binding domain	Ribonuclease P protein subunit p30 GN=RPP30 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribonuclease P protein subunit p30 [Myotis lucifugus] 
ENSG00000148690(FRA10AC1)	--	7.80208	376	7.45099	361	7.94526	377	6.64384	326	6.30583	303	7.59138	366	0.93314465	-0.235657667	normal	0.914329738	-0.272858113	normal	0.968071491	-0.050805468	normal	0.524441549	-0.183811979	normal	--	--	--	"K13121|0|hsa:118924|FRA10AC1, C10orf4, F26C11.1-like, FRA10A; fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1; K13121 protein FRA10AC1 (A)"	--	[S]	Function unknown	Folate-sensitive fragile site protein Fra10Ac1	Protein FRA10AC1 GN=FRA10AC1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FRA10AC1 [Trichechus manatus latirostris]
ENSG00000148700(ADD3)	--	16.82014367	1336	12.56365803	992	13.43681543	1047	6.319774211	505	7.004521895	556	7.098698112	565	2.32E-14	-1.431607957	down	0.000190313	-0.854915396	normal	3.87E-05	-0.89643901	normal	6.57E-07	-1.07450926	down	[G]	Carbohydrate transport and metabolism	--	K18622|0|pps:100974605|ADD3; adducin 3 (gamma); K18622 adducin (A)	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Class II Aldolase and Adducin N-terminal domain	Gamma-adducin GN=ADD3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: gamma-adducin isoform X1 [Ailuropoda melanoleuca] 
ENSG00000148702(HABP2)	--	0	0	0	0	0	0	0.094075138	6	0.015105724	0	0.184535178	12	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	K08648|0|ptr:450744|HABP2; hyaluronan binding protein 2; K08648 hyaluronan binding protein 2 [EC:3.4.21.-] (A)	--	[T]	Signal transduction mechanisms	Trypsin;; Kringle domain;; EGF-like domain	Hyaluronan-binding protein 2 27 kDa light chain alternate form (Precursor) GN=HABP2 OS=Homo sapiens (Human) PE=1 SV=1	ET	Amino acid transport and metabolism;; Signal transduction mechanisms	PREDICTED: hyaluronan-binding protein 2 [Vicugna pacos]
ENSG00000148704(VAX1)	--	1.281881	55	0.8892474	33	0.56422644	27	0.725266001	33	0.679361457	34	0.4176512	20	0.826550399	-0.74078862	normal	0.982640539	0.020707289	normal	0.980040026	-0.414202958	normal	0.568202328	-0.425645702	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09318|1.81519e-172|hsa:11023|VAX1, MCOPS11; ventral anterior homeobox 1; K09318 homeobox protein ventral anterior (A)"	--	[K]	Transcription	Homeobox domain	Ventral anterior homeobox 1 GN=VAX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ventral anterior homeobox 1 [Odobenus rosmarus divergens]
ENSG00000148719(DNAJB12)	--	16.5858064	1170	20.48537144	1435	18.16040863	1292	17.41565246	1204	17.94807098	1270	20.46294402	1439	0.981467078	0.010481031	normal	0.964660915	-0.197427467	normal	0.97464329	0.147005965	normal	0.964587023	-0.014799911	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09518|0|hsa:54788|DNAJB12, DJ10; DnaJ (Hsp40) homolog, subfamily B, member 12; K09518 DnaJ homolog subfamily B member 12 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF1977);; DnaJ domain	DnaJ homolog subfamily B member 12 GN=DNAJB12 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: dnaJ homolog subfamily B member 12 [Pteropus alecto]
ENSG00000148730(EIF4EBP2)	--	9.6077	1068	10.1218	1119	9.82706	1071	17.2725	1923	16.0032	1767	17.6223	1958	0.000193328	0.816727517	normal	0.031125359	0.636974834	normal	4.74E-05	0.861218046	normal	2.43E-08	0.77253292	normal	--	--	Molecular Function: eukaryotic initiation factor 4E binding (GO:0008190);; Biological Process: negative regulation of translational initiation (GO:0045947);; 	K18644|1.16234e-75|ptr:100610028|EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2; K18644 eukaryotic translation initiation factor 4E binding protein 2 (A)	RNA transport (ko03013)	--	--	Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)	Eukaryotic translation initiation factor 4E-binding protein 2 GN=EIF4EBP2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	eukaryotic translation initiation factor 4E-binding protein 2 [Bos taurus] 
ENSG00000148734(NPFFR1)	--	0.00643818	1	0	0	0	0	0	0	0	0	0.00639255	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04240|0|hsa:64106|NPFFR1, GPR147, NPFF1, NPFF1R1, OT7T022; neuropeptide FF receptor 1; K04240 neuropeptide FF receptor 1 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuropeptide FF receptor 1 GN=NPFFR1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuropeptide FF receptor 1 isoform X2 [Bubalus bubalis]
ENSG00000148735(PLEKHS1)	--	0.049049113	4	0.112689873	7	0.015795421	0	0.016273644	1	0.101898174	5	0.030971019	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Pleckstrin homology domain	Pleckstrin homology domain-containing family S member 1 GN=PLEKHS1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family S member 1 [Trichechus manatus latirostris]
ENSG00000148737(TCF7L2)	--	9.483934332	549	10.10935618	636	10.79571057	649	8.977137008	499	8.295082842	527	8.948360865	529	0.956837922	-0.168104865	normal	0.900187096	-0.291886624	normal	0.88994114	-0.302460128	normal	0.224920498	-0.258938776	normal	--	--	--	"K04491|0|hgl:101710380|Tcf7l2; transcription factor 7-like 2 (T-cell specific, HMG-box); K04491 transcription factor 7-like 2 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Melanogenesis (ko04916);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Basal cell carcinoma (ko05217);; Acute myeloid leukemia (ko05221);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[K]	Transcription	N-terminal CTNNB1 binding;; HMG (high mobility group) box;; HMG-box domain	Transcription factor 7-like 2 GN=TCF7L2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor 7-like 2 isoform X1 [Orycteropus afer afer]
ENSG00000148773(MKI67)	--	31.985297	11190	32.884574	11257	34.641832	11857	34.3419022	11798	32.34084	11223	29.729264	10401	0.996533689	0.045493931	normal	0.996413314	-0.025787116	normal	0.992157462	-0.197281346	normal	0.835102099	-0.059043075	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17582|0|ggo:101126693|MKI67; antigen KI-67 isoform 1; K17582 antigen KI-67 (A)	--	--	--	K167R (NUC007) repeat;; Protein phosphatase 1 binding;; FHA domain	Antigen KI-67 GN=MKI67 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: antigen KI-67 [Galeopterus variegatus]
ENSG00000148798(INA)	--	48.6708	2130	65.6965	3072	54.9575	2580	34.46015	1634	31.72089	1419	36.7699	1680	0.713801138	-0.412936478	normal	2.08E-09	-1.134886822	down	0.031973965	-0.626742428	normal	0.001966217	-0.738647322	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07608|0|hsa:9118|INA, NEF5, NF-66, TXBP-1; internexin neuronal intermediate filament protein, alpha; K07608 internexin neuronal intermediate filament protein, alpha (A)"	--	--	--	Intermediate filament protein;; Intermediate filament head (DNA binding) region	Alpha-internexin GN=INA OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: alpha-internexin [Loxodonta africana]
ENSG00000148803(FUOM)	--	7.806649303	80	5.660735	57	7.45217	74	8.050240221	76	9.904615	96	4.1590534	39	0.971843741	-0.102806732	normal	0.577192468	0.71586087	normal	0.392911675	-0.906405521	normal	0.989052177	-0.022311563	normal	--	--	Biological Process: monosaccharide metabolic process (GO:0005996);; Molecular Function: isomerase activity (GO:0016853);; Molecular Function: monosaccharide binding (GO:0048029);; 	"K02431|4.2632e-106|hsa:282969|FUOM, C10orf125, FUCU, FucM; fucose mutarotase (EC:5.1.3.n2); K02431 L-fucose mutarotase [EC:5.1.3.29] (A)"	--	--	--	RbsD / FucU transport protein family	Fucose mutarotase GN=FUOM OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: fucose mutarotase isoform X1 [Tupaia chinensis] 
ENSG00000148814(LRRC27)	--	3.804976764	182	3.17294851	156	2.980984	147	2.646893949	140	2.82392443	154	3.317439533	165	0.846771501	-0.405428768	normal	0.965917945	-0.039655321	normal	0.958880209	0.156834766	normal	0.840331581	-0.100380867	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[K]	Transcription	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 27 GN=LRRC27 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 27 [Ceratotherium simum simum]
ENSG00000148824(MTG1)	--	31.91720795	895	30.82741794	912	30.10819256	879	30.15072101	852	29.92521366	839	28.51667649	812	0.973596416	-0.101687567	normal	0.968366205	-0.141544771	normal	0.97101458	-0.122455615	normal	0.59683371	-0.123180859	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	50S ribosome-binding GTPase;; Ferrous iron transport protein B;; Ethanolamine utilisation - propanediol utilisation;; Elongation factor Tu GTP binding domain	Mitochondrial ribosome-associated GTPase 1 (Precursor) GN=MTG1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: mitochondrial ribosome-associated GTPase 1 [Eptesicus fuscus]
ENSG00000148826(NKX6-2)	--	0.131366	5	0.277837	11	0.0981064	3	0.127846	5	0.250698	9	0.331529	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09350|1.66499e-165|hsa:84504|NKX6-2, GTX, NKX6.2, NKX6B; NK6 homeobox 2; K09350 homeobox protein Nkx-6.2 (A)"	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-6.2 GN=NKX6-2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein Nkx-6.2 [Ceratotherium simum simum]
ENSG00000148834(GSTO1)	--	82.712847	1189	82.194337	1214	89.89947451	1341	133.5277535	1996	109.5381252	1567	102.1652994	1474	0.0034061	0.715809512	normal	0.860253336	0.346429453	normal	0.977412841	0.127998119	normal	0.047676909	0.405995469	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K00799|8.39289e-177|ptr:450719|GSTO1; glutathione S-transferase omega 1 (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Glutathione S-transferase omega-1 GN=GSTO1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase omega-1 isoform 1 [Canis lupus familiaris]
ENSG00000148835(TAF5)	--	2.61015	153	2.4868	147	2.08418	122	2.37828	142	2.54012	149	2.64786	156	0.961744959	-0.137043976	normal	0.966641761	-0.001910857	normal	0.909305021	0.342608922	normal	0.912506757	0.0617871	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03130|0|hsa:6877|TAF5, TAF2D, TAFII100; TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa; K03130 transcription initiation factor TFIID subunit 5 (A)"	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	"WD domain, G-beta repeat;; WD40 associated region in TFIID subunit;; Nucleoporin Nup120/160"	Transcription initiation factor TFIID subunit 5 GN=TAF5 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 5 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000148840(PPRC1)	--	20.330355	2034	18.79860853	1916	18.005924	1889	17.982624	1879	19.529147	2045	16.283882	1802	0.979910707	-0.145072816	normal	0.985011597	0.072521314	normal	0.984480513	-0.076252623	normal	0.849439103	-0.049514502	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K17963|0|pps:100983135|PPRC1; peroxisome proliferator-activated receptor gamma, coactivator-related 1; K17963 peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (A)"	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 GN=PPRC1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1 [Equus caballus]
ENSG00000148841(ITPRIP)	--	11.81223892	1183	10.90392207	1059	12.450687	1217	18.135704	1753	17.74563002	1735	25.92713371	2521	0.198329957	0.535968547	normal	0.008893204	0.69002933	normal	6.27E-08	1.041456685	up	0.011428352	0.776828206	normal	--	--	--	--	--	--	--	Mab-21 protein	"Inositol 1,4,5-trisphosphate receptor-interacting protein (Precursor) GN=ITPRIP OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: inositol 1,4,5-trisphosphate receptor-interacting protein [Galeopterus variegatus]"
ENSG00000148842(CNNM2)	--	5.932618	604	6.88977	699	6.421272643	663	3.367239	384	5.150327147	518	6.79382	666	0.022519331	-0.682078214	normal	0.566305789	-0.452624727	normal	0.974896942	-0.001774098	normal	0.272567575	-0.34588037	normal	[R]	General function prediction only	--	K16302|0|ptr:450705|CNNM2; cyclin and CBS domain divalent metal cation transport mediator 2; K16302 metal transporter CNNM (A)	--	[S]	Function unknown	Domain of unknown function DUF21;; CBS domain	Metal transporter CNNM2 GN=CNNM2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: metal transporter CNNM2 isoform X1 [Chrysochloris asiatica]
ENSG00000148843(PDCD11)	--	14.41573	2231	15.39998	2413	16.27025	2530	17.52455	2696	16.2615	2488	14.14211	2169	0.963991734	0.242145847	normal	0.988219299	0.022717991	normal	0.966793372	-0.230249974	normal	0.965782714	0.013864509	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: nucleus (GO:0005634);; Biological Process: mRNA processing (GO:0006397);; 	"K14792|0|hsa:22984|PDCD11, ALG-4, ALG4, NFBP, RRP5; programmed cell death 11; K14792 rRNA biogenesis protein RRP5 (A)"	--	[A]	RNA processing and modification	S1 RNA binding domain;; Suppressor of forked protein (Suf);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Protein RRP5 homolog GN=PDCD11 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: protein RRP5 homolog isoform X2 [Galeopterus variegatus]
ENSG00000148848(ADAM12)	--	6.90127954	440	5.743014006	424	3.943830563	407	7.794570003	576	6.979358713	515	5.694892882	503	0.819547266	0.35664183	normal	0.922034151	0.258244759	normal	0.895445347	0.296246265	normal	0.16099349	0.304962541	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K06835|0|hsa:8038|ADAM12, ADAM12-OT1, CAR10, MCMP, MCMPMltna, MLTN, MLTNA; ADAM metallopeptidase domain 12; K06835 disintegrin and metalloproteinase domain-containing protein 12 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Reprolysin family propeptide;; Disintegrin;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 12 (Precursor) GN=ADAM12 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 12 isoform X1 [Equus caballus]
ENSG00000148908(RGS10)	--	27.42003534	318	22.57142723	285	27.30067222	323	17.69678381	230	18.66042912	244	13.25215002	178	0.548161464	-0.495396972	normal	0.930880295	-0.244105801	normal	0.00313996	-0.862427701	normal	0.029586799	-0.527817314	normal	--	--	--	K16449|1.47567e-111|hsa:6001|RGS10; regulator of G-protein signaling 10; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 10 GN=RGS10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 10 isoform 1 [Sus scrofa]
ENSG00000148925(BTBD10)	--	14.287557	622	16.00766029	693	15.38295862	685	23.96691693	1042	20.81893899	912	19.2897554	851	0.005872114	0.712163583	normal	0.789640882	0.374038419	normal	0.891752028	0.30416013	normal	0.004651101	0.466224987	normal	--	--	--	K10482|0|pon:100189693|DKFZP459H1039 protein; K10482 BTB/POZ domain-containing protein 10 (A)	--	[R]	General function prediction only	--	BTB/POZ domain-containing protein 10 GN=BTBD10 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 10 isoform X1 [Tupaia chinensis]
ENSG00000148926(ADM)	--	38.5980006	1029	47.59523632	1151	38.43361791	1051	34.89110168	910	29.208757	759	46.91889347	1238	0.955308251	-0.207806572	normal	0.049238602	-0.621129865	normal	0.951792336	0.22765507	normal	0.642378386	-0.172850605	normal	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K12333|3.42816e-120|ptr:451021|ADM; adrenomedullin; K12333 adrenomedullin (A)	--	--	--	Calcitonin / CGRP / IAPP family	Proadrenomedullin N-20 terminal peptide (Precursor) GN=ADM OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ADM [Ceratotherium simum simum]
ENSG00000148935(GAS2)	--	0.292050723	5	0	0	0.097986343	0	0.028745977	1	0.106890573	3	0.08348747	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: microtubule binding (GO:0008017);; 	--	--	[Z]	Cytoskeleton	Growth-Arrest-Specific Protein 2 Domain;; Calponin homology (CH) domain	Growth arrest-specific protein 2 GN=GAS2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: growth arrest-specific protein 2 isoform X2 [Myotis davidii] 
ENSG00000148942(SLC5A12)	--	0.00914768	1	0.0182954	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[ER]	Amino acid transport and metabolism;; General function prediction only	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14388|0|hsa:159963|SLC5A12, SMCT2; solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12; K14388 solute carrier family 5 (sodium-coupled monocarboxylate transporter), member 8/12 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium-coupled monocarboxylate transporter 2 GN=SLC5A12 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-coupled monocarboxylate transporter 2 [Panthera tigris altaica]
ENSG00000148943(LIN7C)	--	11.561037	683	13.55385395	802	11.374161	656	12.90178613	778	12.5718387	745	11.44974532	680	0.963480664	0.156721833	normal	0.96856882	-0.127538771	normal	0.974156947	0.043449106	normal	0.956980171	0.019351261	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	PDZ domain (Also known as DHR or GLGF);; L27 domain	Protein lin-7 homolog C GN=LIN7C OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein lin-7 homolog C [Trichechus manatus latirostris]
ENSG00000148950(IMMP1L)	--	10.046333	112	12.140896	82	15.58735074	91	18.052108	112	23.65297755	106	18.89934	104	0.9697512	-0.030415029	normal	0.931384187	0.343359294	normal	0.963030026	0.181529862	normal	0.785599926	0.154630418	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K09647|8.00461e-121|ptr:466478|IMMP1L; IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae); K09647 mitochondrial inner membrane protease subunit 1 [EC:3.4.21.-] (A)	Protein export (ko03060)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Peptidase S24-like;; Signal peptidase, peptidase S26"	Mitochondrial inner membrane protease subunit 1 GN=IMMP1L OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial inner membrane protease subunit 1 isoform X1 [Galeopterus variegatus]
ENSG00000148985(PGAP2)	--	27.09288434	665	20.42063325	557	25.33109843	641	21.09284979	511	17.90449457	478	21.64961537	546	0.694775499	-0.40977966	normal	0.931606459	-0.241384998	normal	0.934579774	-0.239102935	normal	0.142952324	-0.300290746	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Frag1/DRAM/Sfk1 family	Post-GPI attachment to proteins factor 2 GN=PGAP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: post-GPI attachment to proteins factor 2 isoform X5 [Ailuropoda melanoleuca]
ENSG00000149016(TUT1)	--	7.885984803	443	8.913084785	406	8.446315019	435	8.005263183	413	7.615575679	404	7.006046469	379	0.961617721	-0.131524593	normal	0.96865659	-0.028444779	normal	0.944482567	-0.206339826	normal	0.679827713	-0.123800955	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; 	"K18709|0|hsa:64852|TUT1, PAPD2, RBM21, STARPAP, TUTase; terminal uridylyl transferase 1, U6 snRNA-specific (EC:2.7.7.19 2.7.7.52); K18709 speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; Cid1 family poly A polymerase;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Zinc-finger of C2H2 type"	Speckle targeted PIP5K1A-regulated poly(A) polymerase GN=TUT1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: speckle targeted PIP5K1A-regulated poly(A) polymerase [Equus przewalskii]
ENSG00000149043(SYT8)	--	0	0	0.148296	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-8 GN=SYT8 OS=Homo sapiens (Human) PE=2 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-8 [Mustela putorius furo]
ENSG00000149050(ZNF214)	--	0.484616343	24	0.719518459	35	0.501139969	23	0.343421177	16	0.466286854	23	0.393224941	20	0.976987289	-0.570754908	normal	0.953953764	-0.595198856	normal	0.986945332	-0.196088414	normal	0.53154345	-0.495855676	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7761|ZNF214, BAZ-1, BAZ1; zinc finger protein 214; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc ribbon domain"	Zinc finger protein 214 GN=ZNF214 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 214 [Ceratotherium simum simum]
ENSG00000149054(ZNF215)	--	1.300174732	75	1.559864357	89	1.724794068	93	0.845741565	47	0.730090859	39	0.722118993	43	0.755790894	-0.687112915	normal	0.020262346	-1.180601754	normal	0.039430443	-1.094382507	normal	0.015575802	-1.01574008	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:7762|ZNF215, BAZ-2, BAZ2, ZKSCAN11, ZSCAN43; zinc finger protein 215; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 215 GN=ZNF215 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 215 [Ceratotherium simum simum]
ENSG00000149084(HSD17B12)	--	77.511177	2574	85.541004	2743	77.65452	2406	73.945468	2462	79.135142	2296	82.34852	2793	0.9866876	-0.094955592	normal	0.950152671	-0.277890824	normal	0.974551945	0.206766763	normal	0.833604957	-0.05353129	normal	[R]	General function prediction only	--	"K10251|0|hsa:51144|HSD17B12, KAR, SDR12C1; hydroxysteroid (17-beta) dehydrogenase 12 (EC:1.1.1.62); K10251 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase [EC:1.1.1.62 1.1.1.330] (A)"	Fatty acid elongation (ko00062);; Steroid hormone biosynthesis (ko00140);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Estradiol 17-beta-dehydrogenase 12 GN=HSD17B12 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: estradiol 17-beta-dehydrogenase 12 [Orycteropus afer afer]
ENSG00000149089(APIP)	--	21.1536	451	20.72581	445	22.34668	478	23.1441	489	22.6643	465	20.3976	431	0.967713757	0.085594696	normal	0.969311668	0.041859658	normal	0.957902742	-0.157090536	normal	0.985435375	-0.009939149	normal	[G]	Carbohydrate transport and metabolism	--	K08964|2.31508e-171|ptr:451118|APIP; APAF1 interacting protein; K08964 methylthioribulose-1-phosphate dehydratase [EC:4.2.1.109] (A)	Cysteine and methionine metabolism (ko00270)	[G]	Carbohydrate transport and metabolism	Class II Aldolase and Adducin N-terminal domain	Methylthioribulose-1-phosphate dehydratase {ECO:0000255|HAMAP-Rule:MF_03116} OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: methylthioribulose-1-phosphate dehydratase [Vicugna pacos]
ENSG00000149091(DGKZ)	--	12.29798732	984	12.92559846	1044	13.84190176	1025	14.07665427	1126	13.95621587	1115	14.86138751	1173	0.967868371	0.163405708	normal	0.977977603	0.07339256	normal	0.963866893	0.186030913	normal	0.51479596	0.140168972	normal	--	--	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|hsa:8525|DGKZ, DAGK5, DAGK6, DGK-ZETA, hDGKzeta; diacylglycerol kinase, zeta (EC:2.7.1.107); K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Phorbol esters/diacylglycerol binding domain (C1 domain);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Diacylglycerol kinase zeta GN=DGKZ OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: diacylglycerol kinase zeta isoform X4 [Felis catus]
ENSG00000149100(EIF3M)	--	139.3102515	2861	125.0991231	2767	145.3206153	2870	153.9908526	3099	165.4086258	3194	131.7635225	2692	0.988661261	0.084407435	normal	0.98020828	0.185520674	normal	0.987325682	-0.10060902	normal	0.815018457	0.058887268	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15030|0|umr:103659345|EIF3M; eukaryotic translation initiation factor 3, subunit M; K15030 translation initiation factor 3 subunit M (A)"	--	[R]	General function prediction only	PCI domain	Eukaryotic translation initiation factor 3 subunit M {ECO:0000255|HAMAP-Rule:MF_03012} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit M [Ochotona princeps]
ENSG00000149115(TNKS1BP1)	--	25.864603	3268	25.5682021	3594	31.03167472	3281	34.959641	3832	37.42853587	4246	43.75723	4514	0.980797698	0.198770948	normal	0.978770047	0.219002543	normal	0.648398535	0.451801116	normal	0.080831615	0.291243866	normal	--	--	--	--	--	--	--	Tankyrase binding protein C terminal domain	182 kDa tankyrase-1-binding protein GN=TNKS1BP1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: 182 kDa tankyrase-1-binding protein [Galeopterus variegatus]
ENSG00000149131(SERPING1)	--	0.696171678	22	0.67781083	12	0.058418113	1	0.20643921	7	0.384386599	11	0.2031343	5	0.758230056	-1.490238979	normal	--	--	--	--	--	--	--	--	--	--	--	--	"K04001|0|hsa:710|SERPING1, C1IN, C1INH, C1NH, HAE1, HAE2; serpin peptidase inhibitor, clade G (C1 inhibitor), member 1; K04001 C1 inhibitor (A)"	Complement and coagulation cascades (ko04610);; Pertussis (ko05133)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Plasma protease C1 inhibitor (Precursor) GN=SERPING1 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: plasma protease C1 inhibitor [Galeopterus variegatus]
ENSG00000149136(SSRP1)	--	90.56830976	6073	89.10039241	6004	93.62332797	6115	95.11032311	6328	90.74340916	6023	86.36760223	5736	0.99438504	0.028500903	normal	0.994091288	-0.016864035	normal	0.992891406	-0.100573231	normal	0.919487731	-0.029811431	normal	[KLB]	"Transcription;; Replication, recombination and repair;; Chromatin structure and dynamics"	--	K09272|0|pps:100970621|SSRP1; structure specific recognition protein 1; K09272 structure-specific recognition protein 1 (A)	--	[KLB]	"Transcription;; Replication, recombination and repair;; Chromatin structure and dynamics"	Structure-specific recognition protein (SSRP1);; Histone chaperone Rttp106-like;; HMG (high mobility group) box;; HMG-box domain	FACT complex subunit SSRP1 GN=SSRP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: FACT complex subunit SSRP1 isoform X2 [Tupaia chinensis]
ENSG00000149150(SLC43A1)	--	1.389675597	62	0.703169423	31	0.739446074	33	1.390286104	55	1.507463779	57	1.542297677	63	0.971868764	-0.198443645	normal	0.725258699	0.827103205	normal	0.560026725	0.894451262	normal	0.442492322	0.452728288	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08228|0|hsa:8501|SLC43A1, LAT3, PB39, POV1, R00504; solute carrier family 43 (amino acid system L transporter), member 1; K08228 MFS transporter, LAT3 family, solute carrier family 43, member 1 (A)"	--	--	--	Major Facilitator Superfamily	Large neutral amino acids transporter small subunit 3 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: large neutral amino acids transporter small subunit 3 isoform X2 [Galeopterus variegatus]
ENSG00000149177(PTPRJ)	--	29.01823205	4044	30.93646578	4419	27.53564516	3879	20.25311601	2906	18.37323249	2620	20.02405043	2935	0.366207601	-0.507352001	normal	0.000781449	-0.775230975	normal	0.779294588	-0.41043114	normal	8.28E-05	-0.56605475	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K05698|0|ptr:451181|PTPRJ; protein tyrosine phosphatase, receptor type, J; K05698 receptor-type tyrosine-protein phosphatase eta [EC:3.1.3.48] (A)"	Adherens junction (ko04520)	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Fibronectin type III domain;; Interferon-alpha/beta receptor, fibronectin type III"	Receptor-type tyrosine-protein phosphatase eta (Precursor) GN=PTPRJ OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase eta [Oryctolagus cuniculus]
ENSG00000149179(C11orf49)	--	22.75914799	671	21.276733	636	20.39306943	626	22.19877	619	27.747807	790	22.174456	579	0.963602775	-0.146855375	normal	0.904019206	0.290777921	normal	0.966848113	-0.120587756	normal	0.960928484	0.019185585	normal	--	--	--	--	--	--	--	--	UPF0705 protein C11orf49 GN=C11orf49 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"hypothetical protein M91_11657, partial [Bos mutus]"
ENSG00000149182(ARFGAP2)	--	11.88417577	649	9.60778522	563	10.9302087	590	14.72650099	800	15.15226017	763	13.38952216	689	0.918960845	0.270371918	normal	0.683061921	0.416158037	normal	0.945862512	0.214987185	normal	0.121039723	0.29996601	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; 	K12493|0|ggo:101124521|ARFGAP2; ADP-ribosylation factor GTPase-activating protein 2 isoform 1; K12493 ADP-ribosylation factor GTPase-activating protein 2/3 (A)	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf	ADP-ribosylation factor GTPase-activating protein 2 GN=ARFGAP2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor GTPase-activating protein 2 [Galeopterus variegatus]
ENSG00000149187(CELF1)	--	22.25639713	2315	24.91130963	2475	25.60224452	2478	27.54973758	2690	28.83779203	2772	30.56465081	3023	0.977808077	0.185647339	normal	0.983581624	0.141990163	normal	0.951662675	0.278359306	normal	0.264835604	0.202563961	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13207|0|pale:102881887|CELF1; CUGBP, Elav-like family member 1; K13207 CUG-BP- and ETR3-like factor (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding domain"	CUGBP Elav-like family member 1 GN=CELF1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	"PREDICTED: CUGBP, Elav-like family member 1 isoform X3 [Equus caballus] "
ENSG00000149196(HIKESHI)	--	23.158156	357	25.92893919	409	25.84352917	395	28.822161	441	28.572604	446	27.571397	389	0.913117166	0.272963793	normal	0.964433663	0.103151	normal	0.969230228	-0.030257206	normal	0.709106598	0.114765754	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF775)	Protein Hikeshi GN=C11orf73 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein Hikeshi [Ailuropoda melanoleuca] 
ENSG00000149201(CCDC81)	--	0.128348635	6	0.06880414	4	0.229011436	3	0.142351532	6	0.03404581	1	0.087351438	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4496)	Coiled-coil domain-containing protein 81 GN=CCDC81 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 81 [Ceratotherium simum simum]
ENSG00000149212(SESN3)	--	1.566386853	216	1.372756386	176	1.544294646	207	0.615866446	85	0.912595394	125	0.442485199	61	1.20E-06	-1.36032671	down	0.698686767	-0.509848601	normal	4.94E-10	-1.74608177	down	3.32E-05	-1.165832471	down	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of response to reactive oxygen species (GO:1901031);; 	K10141|0|pps:100979216|SESN3; sestrin 3; K10141 sestrin (A)	p53 signaling pathway (ko04115)	[S]	Function unknown	PA26 p53-induced protein (sestrin)	Sestrin-3 GN=SESN3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: sestrin-3 isoform 1 [Orcinus orca] 
ENSG00000149218(ENDOD1)	--	4.83014	385	4.69509	377	5.6864	450	6.71173	538	6.10998	485	5.93021	473	0.590139909	0.450388846	normal	0.849532481	0.340785652	normal	0.969243202	0.063415852	normal	0.214012566	0.282426947	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; 	K15049|0|hsa:23052|ENDOD1; endonuclease domain containing 1; K15049 endonuclease domain-containing 1 protein (A)	--	--	--	DNA/RNA non-specific endonuclease	Endonuclease domain-containing 1 protein (Precursor) GN=ENDOD1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: endonuclease domain-containing 1 protein [Galeopterus variegatus]
ENSG00000149231(CCDC82)	--	8.95950607	399	9.971918166	483	13.07390551	554	10.76284445	525	9.749802022	457	11.12154549	526	0.810097443	0.363871699	normal	0.965594428	-0.100930642	normal	0.969493248	-0.082882395	normal	0.887063668	0.049720062	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF4196);; Domain of unknown function (DUF4211)	Coiled-coil domain-containing protein 82 GN=CCDC82 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 82 isoform X4 [Canis lupus familiaris] 
ENSG00000149243(KLHL35)	--	0.876796479	19	0.504386066	12	0.476391464	10	0.88828592	20	0.970090758	21	1.455149	38	--	--	--	0.97262599	0.716933044	normal	0.050063853	1.771538664	normal	--	--	--	--	--	--	K10461|1.4713e-32|hsa:283212|KLHL35; kelch-like family member 35; K10461 kelch-like protein 24/35 (A)	--	--	--	--	Kelch-like protein 35 GN=KLHL35 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 35 [Leptonychotes weddellii]
ENSG00000149256(TENM4)	--	0.007901304	2	0.011806587	3	0	0	0.020373002	6	0.024168036	6	0.016753684	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Teneurin Intracellular Region;; GHH signature containing HNH/Endo VII superfamily nuclease toxin;; EGF-like domain;; NHL repeat;; RHS Repeat;; Human growth factor-like EGF	Teneurin-4 GN=TENM4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: teneurin-4 [Canis lupus familiaris]
ENSG00000149257(SERPINH1)	--	44.83536352	1584	42.5356006	1703	44.01105708	1720	73.09714055	2883	67.14718	2587	62.82345362	2444	9.53E-05	0.832559324	normal	0.103735334	0.581353372	normal	0.361417489	0.498174998	normal	4.88E-06	0.638820096	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09501|0|ptr:466899|SERPINH1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); K09501 serpin peptidase inhibitor, clade H, member 1 (A)"	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin H1 (Precursor) GN=SERPINH1 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	"serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) [Canis lupus familiaris]"
ENSG00000149260(CAPN5)	--	10.74982474	716	6.814749654	503	9.548687046	608	4.833283497	364	5.562374414	456	4.33276934	323	4.33E-06	-1.003771247	down	0.956534642	-0.162437949	normal	9.18E-05	-0.917644033	normal	0.008081541	-0.69794866	normal	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K08574|0|hsa:726|CAPN5, ADNIV, HTRA3, VRNI, nCL-3; calpain 5; K08574 calpain-5 [EC:3.4.22.-] (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III;; C2 domain"	Calpain-5 GN=CAPN5 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-5 [Galeopterus variegatus]
ENSG00000149262(INTS4)	--	12.93828	577	12.37464666	526	11.940803	605	10.93666006	506	11.2623	578	11.939976	556	0.94172825	-0.219641065	normal	0.965863647	0.114266663	normal	0.965144376	-0.129803131	normal	0.788563773	-0.079287524	normal	--	--	--	K13141|0|ptr:451444|INTS4; integrator complex subunit 4; K13141 integrator complex subunit 4 (A)	--	[S]	Function unknown	HEAT repeat;; HEAT repeats;; Adaptin N terminal region;; non-SMC mitotic condensation complex subunit 1;; HEAT-like repeat;; Vacuolar 14 Fab1-binding region;; HEAT repeat associated with sister chromatid cohesion;; CLASP N terminal	Integrator complex subunit 4 GN=INTS4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: integrator complex subunit 4 isoform X2 [Mustela putorius furo]
ENSG00000149269(PAK1)	--	14.82327919	998	12.57187626	853	15.42467402	1022	15.21407866	961	14.0162563	951	12.0078327	798	0.976440436	-0.085201962	normal	0.969706219	0.135245877	normal	0.805629281	-0.364613785	normal	0.657499515	-0.105749629	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04409|0|hsa:5058|PAK1, PAKalpha; p21 protein (Cdc42/Rac)-activated kinase 1 (EC:2.7.11.1); K04409 p21-activated kinase 1 [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Axon guidance (ko04360);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Proteoglycans in cancer (ko05205);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; P21-Rho-binding domain;; Kinase-like	Serine/threonine-protein kinase PAK 1 GN=PAK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase PAK 1 isoform 1 [Ovis aries]
ENSG00000149273(RPS3)	--	1176.028162	19425	1055.59083	18432	1105.26695	18975	1332.405966	22042	1259.068075	20697	1220.075105	20120	0.996703095	0.151497018	normal	0.996527984	0.145771195	normal	0.997568957	0.076233076	normal	0.62496329	0.123957229	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02985|0|mcf:101926445|uncharacterized LOC101926445; K02985 small subunit ribosomal protein S3e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein S3, C-terminal domain;; KH domain"	40S ribosomal protein S3 GN=RPS3 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S3 isoform X1 [Bos mutus]
ENSG00000149289(ZC3H12C)	--	3.975333079	558	4.297975977	622	4.115083696	568	4.12570704	594	4.27124002	600	6.85062	965	0.971650789	0.05920753	normal	0.970880346	-0.073197422	normal	0.002237751	0.754787157	normal	0.55303736	0.284833176	normal	--	--	--	K18668|0|pps:100989381|ZC3H12C; zinc finger CCCH-type containing 12C; K18668 ribonuclease ZC3H12 [EC:3.1.-.-] (A)	--	[S]	Function unknown	Zc3h12a-like Ribonuclease NYN domain	Probable ribonuclease ZC3H12C GN=ZC3H12C OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: probable ribonuclease ZC3H12C isoform X2 [Galeopterus variegatus]
ENSG00000149292(TTC12)	--	3.638991738	184	4.979592021	139	3.020713068	141	2.869898544	149	3.685462075	180	3.011383673	155	0.90357826	-0.332136998	normal	0.894667522	0.348148915	normal	0.962585729	0.126982218	normal	0.9508736	0.039721548	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 12 GN=TTC12 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tetratricopeptide repeat protein 12 [Galeopterus variegatus]
ENSG00000149294(NCAM1)	--	0.046965798	6	0.155659405	2	0.007739273	0	0.031024477	3	0.024823617	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K06491|0|pon:100439394|NCAM1; neural cell adhesion molecule 1; K06491 neural cell adhesion molecule (A)	Cell adhesion molecules (CAMs) (ko04514);; Prion diseases (ko05020)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Fibronectin type III domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Neural cell adhesion molecule 1 (Precursor) GN=NCAM1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neural cell adhesion molecule 1 isoform X1 [Chrysochloris asiatica]
ENSG00000149295(DRD2)	--	0	0	0	0	0	0	0.021518131	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04145|0|pps:100980993|DRD2; dopamine receptor D2; K04145 dopamine receptor D2 (A)	Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Gap junction (ko04540);; Dopaminergic synapse (ko04728);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Alcoholism (ko05034)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv	D(2) dopamine receptor GN=DRD2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: D(2) dopamine receptor isoform X3 [Equus caballus] 
ENSG00000149308(NPAT)	--	3.7146604	394	4.46224	473	5.082789	487	4.569678	439	3.10533	337	3.54417	385	0.962348823	0.124732116	normal	0.418662248	-0.508581796	normal	0.84035858	-0.346142958	normal	0.322515551	-0.243391827	normal	--	--	--	--	--	--	--	--	Protein NPAT GN=NPAT OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: protein NPAT isoform X1 [Galeopterus variegatus]
ENSG00000149311(ATM)	--	7.930922055	1425	8.622374	1574	9.463933391	1597	7.19101922	1335	7.359244121	1353	9.807538165	1566	0.977439373	-0.124815363	normal	0.952939116	-0.239451838	normal	0.984223729	-0.036536602	normal	0.526831031	-0.132186382	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: kinase activity (GO:0016301);; 	"K04728|0|hsa:472|ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1; ATM serine/threonine kinase (EC:2.7.11.1); K04728 ataxia telangiectasia mutated family protein [EC:2.7.11.1] (A)"	NF-kappa B signaling pathway (ko04064);; FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; p53 signaling pathway (ko04115);; Apoptosis (ko04210);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202);; MicroRNAs in cancer (ko05206)	[TBLD]	"Signal transduction mechanisms;; Chromatin structure and dynamics;; Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	FAT domain;; Phosphatidylinositol 3- and 4-kinase;; Telomere-length maintenance and DNA damage repair;; FATC domain	Serine-protein kinase ATM GN=ATM OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: serine-protein kinase ATM [Galeopterus variegatus]
ENSG00000149313(AASDHPPT)	--	24.56015578	993	22.5232274	930	25.260891	1026	19.03391621	774	19.08159165	785	19.18687741	782	0.745222455	-0.389607553	normal	0.926432501	-0.265494061	normal	0.719930541	-0.399405179	normal	0.038781906	-0.354118784	normal	[H]	Coenzyme transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: holo-[acyl-carrier-protein] synthase activity (GO:0008897);; 	K06133|0|pps:100987992|AASDHPPT; aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; K06133 4'-phosphopantetheinyl transferase [EC:2.7.8.-] (A)	Pantothenate and CoA biosynthesis (ko00770)	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	4'-phosphopantetheinyl transferase superfamily	L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase GN=AASDHPPT OS=Homo sapiens (Human) PE=1 SV=2	EH	Amino acid transport and metabolism;; Coenzyme transport and metabolism	PREDICTED: L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase [Galeopterus variegatus]
ENSG00000149328(GLB1L2)	--	0.824471752	52	0.667923889	43	0.47651296	30	0.696523529	44	0.78888731	49	0.7312696	47	0.971991245	-0.263369233	normal	0.976173411	0.161688889	normal	0.925746068	0.614472462	normal	0.872319994	0.14184177	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: beta-galactosidase activity (GO:0004565);; Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: beta-galactosidase complex (GO:0009341);; 	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 35;; Beta-galactosidase	Beta-galactosidase-1-like protein 2 (Precursor) GN=GLB1L2 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: beta-galactosidase-1-like protein 2 [Panthera tigris altaica]
ENSG00000149346(SLX4IP)	--	3.93621831	411	4.230250875	437	4.51793836	463	4.679867247	485	4.0635742	422	5.411083795	569	0.944510088	0.207300114	normal	0.967204582	-0.071564798	normal	0.902010563	0.288274243	normal	0.580229312	0.1504031	normal	--	--	--	--	--	--	--	--	Protein SLX4IP GN=SLX4IP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein SLX4IP [Ursus maritimus] 
ENSG00000149357(LAMTOR1)	--	62.19423	1206	68.436418	1369	66.41699	1339	72.992721	1428	65.78549	1263	80.426893	1570	0.959848869	0.212684583	normal	0.974981615	-0.137536131	normal	0.959384608	0.221086333	normal	0.653898038	0.101630914	normal	--	--	Biological Process: regulation of receptor recycling (GO:0001919);; Biological Process: lysosome organization (GO:0007040);; Cellular Component: late endosome membrane (GO:0031902);; Biological Process: positive regulation of TOR signaling (GO:0032008);; Biological Process: endosome localization (GO:0032439);; Biological Process: cholesterol homeostasis (GO:0042632);; Biological Process: positive regulation of MAPK cascade (GO:0043410);; Cellular Component: membrane raft (GO:0045121);; Biological Process: cellular response to amino acid stimulus (GO:0071230);; Cellular Component: Ragulator complex (GO:0071986);; 	--	--	--	--	Late endosomal/lysosomal adaptor and MAPK and MTOR activator	Ragulator complex protein LAMTOR1 GN=LAMTOR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	ragulator complex protein LAMTOR1 [Bos taurus] 
ENSG00000149380(P4HA3)	--	1.891922222	82	3.980738398	134	2.731906666	91	11.17604855	495	17.7492	619	10.368786	402	0	2.54092046	up	0	2.173755196	up	0	2.116687557	up	1.01E-10	2.281976272	up	--	--	"Molecular Function: procollagen-proline 4-dioxygenase activity (GO:0004656);; Molecular Function: protein binding (GO:0005515);; Cellular Component: endoplasmic reticulum (GO:0005783);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00472|0|hsa:283208|P4HA3; prolyl 4-hydroxylase, alpha polypeptide III (EC:1.14.11.2); K00472 prolyl 4-hydroxylase [EC:1.14.11.2] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	"Prolyl 4-Hydroxylase alpha-subunit, N-terminal region;; 2OG-Fe(II) oxygenase superfamily"	Prolyl 4-hydroxylase subunit alpha-3 (Precursor) GN=P4HA3 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: prolyl 4-hydroxylase subunit alpha-3 isoform X1 [Bos taurus]
ENSG00000149403(GRIK4)	--	0	0	0.014208776	1	0	0	0.014349749	1	0.027738619	1	0.070784373	5	--	--	--	--	--	--	--	--	--	--	--	--	[ET]	Amino acid transport and metabolism;; Signal transduction mechanisms	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05204|0|hsa:2900|GRIK4, EAA1, GRIK, GluK4, KA1; glutamate receptor, ionotropic, kainate 4; K05204 glutamate receptor, ionotropic kainate 4 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Receptor family ligand binding region;; Ligand-gated ion channel;; Ligated ion channel L-glutamate- and glycine-binding site;; Bacterial extracellular solute-binding proteins, family 3"	"Glutamate receptor ionotropic, kainate 4 (Precursor) GN=GRIK4 OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, kainate 4 [Canis lupus familiaris]"
ENSG00000149418(ST14)	--	0.0569893	4	0.0830072	6	0.0810743	5	0.112926	8	0.0689216	4	0.0841281	6	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; 	"K08670|0|hsa:6768|ST14, ARCI11, HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14; suppression of tumorigenicity 14 (colon carcinoma) (EC:3.4.21.109); K08670 suppressor of tumorigenicity protein 14 [EC:3.4.21.109] (A)"	MicroRNAs in cancer (ko05206)	[E]	Amino acid transport and metabolism	Trypsin;; Low-density lipoprotein receptor domain class A;; CUB domain;; SEA domain;; CUB-like domain	Suppressor of tumorigenicity 14 protein GN=ST14 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: suppressor of tumorigenicity 14 protein [Ochotona princeps]
ENSG00000149428(HYOU1)	--	27.3203257	2399	29.63909125	2252	30.73704047	2334	35.77492255	2976	33.92759516	3029	31.246402	2726	0.95005754	0.279947882	normal	0.779743904	0.405972353	normal	0.972128629	0.215560201	normal	0.064482582	0.300489951	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	"K09486|0|hsa:10525|HYOU1, GRP-170, Grp170, HSP12A, ORP-150, ORP150; hypoxia up-regulated 1; K09486 hypoxia up-regulated 1 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein	Hypoxia up-regulated protein 1 (Precursor) GN=HYOU1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: hypoxia up-regulated protein 1 isoform 2 [Dasypus novemcinctus]
ENSG00000149474(KAT14)	--	15.02435417	721	16.74879781	770	15.97688276	709	16.57021803	784	17.50410954	785	15.42021067	844	0.972711684	0.089838516	normal	0.976067485	0.006395211	normal	0.937022606	0.242690918	normal	0.64883605	0.112246699	normal	--	--	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	--	--	[R]	General function prediction only	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; FR47-like protein	Cysteine-rich protein 2-binding protein GN=CSRP2BP OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: cysteine-rich protein 2-binding protein-like isoform X1 [Tupaia chinensis]
ENSG00000149476(TKFC)	--	24.606211	1148	20.7515641	976	20.85347	1071	22.309104	922	21.170411	930	22.61118	1013	0.842287252	-0.346597408	normal	0.97521054	-0.090932629	normal	0.977062083	-0.088487254	normal	0.37596098	-0.178144753	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: glycerone kinase activity (GO:0004371);; Biological Process: glycerol metabolic process (GO:0006071);; 	K00863|0|ptr:466626|DAK; dihydroxyacetone kinase 2 homolog (S. cerevisiae); K00863 dihydroxyacetone kinase [EC:2.7.1.29] (A)	Glycerolipid metabolism (ko00561);; Carbon metabolism (ko01200);; RIG-I-like receptor signaling pathway (ko04622)	[G]	Carbohydrate transport and metabolism	Dak1 domain;; DAK2 domain	FAD-AMP lyase (cyclizing) GN=DAK OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: bifunctional ATP-dependent dihydroxyacetone kinase/FAD-AMP lyase (cyclizing) [Galeopterus variegatus]
ENSG00000149480(MTA2)	--	35.53678642	2247	33.35528728	2129	36.65084418	2347	35.38603569	2235	40.86134054	2556	34.71036115	2206	0.987536679	-0.038531139	normal	0.963145765	0.24212818	normal	0.985551745	-0.097611606	normal	0.895315041	0.036618405	normal	--	--	"Molecular Function: chromatin binding (GO:0003682);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K11660|0|ptr:451255|MTA2; metastasis associated 1 family, member 2; K11660 metastasis-associated protein MTA (A)"	--	[B]	Chromatin structure and dynamics	BAH domain;; ELM2 domain;; GATA zinc finger	Metastasis-associated protein MTA2 GN=MTA2 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: metastasis-associated protein MTA2 [Oryctolagus cuniculus]
ENSG00000149483(TMEM138)	--	22.068494	680	20.429991	643	24.312458	751	19.22927	590	18.749206	595	23.320866	724	0.937117121	-0.235081208	normal	0.964778728	-0.133030267	normal	0.97452991	-0.06098956	normal	0.56305018	-0.139945602	normal	--	--	--	--	--	--	--	Transmembrane protein 138	Transmembrane protein 138 GN=TMEM138 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 138 [Galeopterus variegatus]
ENSG00000149485(FADS1)	--	149.6530159	12824	174.2853051	14646	166.1047734	13675	118.7545789	10160	119.6208804	10045	231.2742446	20169	0.94488095	-0.366728698	normal	0.298619168	-0.565384752	normal	0.383475619	0.552256684	normal	0.95908328	-0.046429246	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K10224|0|hsa:3992|FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12; fatty acid desaturase 1 (EC:1.14.19.-); K10224 fatty acid desaturase 1 (delta-5 desaturase) [EC:1.14.19.-] (A)"	Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	Fatty acid desaturase;; Cytochrome b5-like Heme/Steroid binding domain	Fatty acid desaturase 1 GN=FADS1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: fatty acid desaturase 1 [Galeopterus variegatus]
ENSG00000149488(TMC2)	--	0.0152886	1	0	0	0.0745432	4	0	0	0.0148939	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 2 GN=TMC2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane channel-like protein 2 [Ceratotherium simum simum]
ENSG00000149489(ROM1)	--	1.2944283	27	1.814693624	38	2.047967	36	1.906868	29	1.415541	27	1.693914344	35	0.985717951	0.068499814	normal	0.96185756	-0.491165903	normal	0.982775636	-0.046933784	normal	0.858519474	-0.170961678	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17344|1.48669e-165|hsa:6094|ROM1, ROM, ROSP1, RP7, TSPAN23; retinal outer segment membrane protein 1; K17344 rod outer segment membrane protein 1 (A)"	--	[R]	General function prediction only	Tetraspanin family	Rod outer segment membrane protein 1 GN=ROM1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rod outer segment membrane protein 1 [Canis lupus familiaris]
ENSG00000149499(EML3)	--	13.3471174	725	7.474054643	436	9.728982402	588	11.39714023	586	13.4518522	688	9.729723986	504	0.848049066	-0.337116157	normal	0.056604556	0.634886693	normal	0.937776804	-0.230044128	normal	1	0.002364836	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K18596|0|hsa:256364|EML3, ELP95; echinoderm microtubule associated protein like 3; K18596 echinoderm microtubule-associated protein-like 3 (A)"	--	[S]	Function unknown	"HELP motif;; WD domain, G-beta repeat"	Echinoderm microtubule-associated protein-like 3 GN=EML3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: echinoderm microtubule-associated protein-like 3 isoform X1 [Orycteropus afer afer]
ENSG00000149503(INCENP)	--	22.54321734	1963	21.26347067	1943	22.49406554	2073	21.13341	1868	20.33978554	1772	18.36185973	1635	0.983414602	-0.102315873	normal	0.977834292	-0.154208116	normal	0.864073498	-0.350432356	normal	0.265885287	-0.202206968	normal	--	--	--	K11515|0|ggo:101141948|INCENP; inner centromere protein; K11515 inner centromere protein (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Chromosome passenger complex (CPC) protein INCENP N terminal;; Inner centromere protein, ARK binding region"	Inner centromere protein GN=INCENP OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: inner centromere protein [Equus przewalskii]
ENSG00000149506(ZP1)	--	0.0842084	3	0	0	0	0	0	0	0.0547974	1	0.0277924	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zona pellucida-like domain	Processed zona pellucida sperm-binding protein 1 (Precursor) GN=ZP1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: zona pellucida sperm-binding protein 1 [Trichechus manatus latirostris]
ENSG00000149527(PLCH2)	--	0.121500504	12	0.05526456	6	0.03138053	3	0.117575784	10	0.17071272	17	0.068744975	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain;; EF-hand domain pair;; EF hand;; EF-hand domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 GN=PLCH2 OS=Homo sapiens (Human) PE=2 SV=3"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2 [Galeopterus variegatus]"
ENSG00000149532(CPSF7)	--	25.49549405	1758	29.09748371	1855	26.003804	1676	27.2190577	1712	28.44312457	1938	31.32274522	2082	0.984128174	-0.069023499	normal	0.985559517	0.041689574	normal	0.920482564	0.304409579	normal	0.675118181	0.095317311	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K14398|0|mcf:102132185|CPSF7; cleavage and polyadenylation specific factor 7, 59kDa; K14398 cleavage and polyadenylation specificity factor subunit 6/7 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Cleavage and polyadenylation specificity factor subunit 7 GN=CPSF7 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	cleavage and polyadenylation specificity factor subunit 7 isoform 1 [Camelus ferus]
ENSG00000149541(B3GAT3)	--	31.66033848	978	31.36713	960	28.45391917	914	28.15608283	880	26.2260628	806	30.1594457	941	0.961590156	-0.182860164	normal	0.922042282	-0.273210726	normal	0.978315926	0.033654236	normal	0.530590071	-0.13968846	normal	--	--	Molecular Function: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity (GO:0015018);; Cellular Component: membrane (GO:0016020);; 	"K10158|0|ptr:740388|B3GAT3; beta-1,3-glucuronyltransferase 3 (EC:2.4.1.135); K10158 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [EC:2.4.1.135] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532);; Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyltransferase family 43	Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 GN=B3GAT3 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3 [Galeopterus variegatus]
ENSG00000149547(EI24)	--	66.8156622	2101	74.038905	2305	73.4935168	2137	81.22146039	2490	74.019811	2230	87.3387268	2683	0.970630681	0.214093374	normal	0.986487971	-0.069103501	normal	0.916730387	0.319766337	normal	0.422445983	0.157066469	normal	--	--	--	K10134|0|cjc:100403945|EI24; etoposide induced 2.4; K10134 etoposide-induced 2.4 mRNA (A)	p53 signaling pathway (ko04115)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Etoposide-induced protein 2.4 (EI24)	Etoposide-induced protein 2.4 homolog GN=EI24 OS=Homo sapiens (Human) PE=1 SV=4	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: etoposide-induced protein 2.4 homolog [Ceratotherium simum simum] 
ENSG00000149554(CHEK1)	--	17.12780254	686	19.59917695	635	20.83663071	779	17.47448191	655	15.75022057	624	13.7489952	533	0.970622775	-0.097322825	normal	0.972666822	-0.046525344	normal	0.177910327	-0.55446991	normal	0.263814332	-0.234265236	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K02216|0|hsa:1111|CHEK1, CHK1; checkpoint kinase 1 (EC:2.7.11.1); K02216 serine/threonine-protein kinase Chk1 [EC:2.7.11.1] (A)"	Cell cycle (ko04110);; p53 signaling pathway (ko04115);; HTLV-I infection (ko05166);; Viral carcinogenesis (ko05203)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase Chk1 GN=CHEK1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase Chk1 isoform X5 [Physeter catodon]
ENSG00000149557(FEZ1)	--	1.802299349	47	1.2516527	25	1.25708318	35	2.013386	62	2.44865411	71	2.035573807	72	0.95844155	0.358544239	normal	0.008248311	1.430972311	up	0.255158741	1.001568897	normal	0.052381932	0.917384038	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	FEZ-like protein	Fasciculation and elongation protein zeta-1 GN=FEZ1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: fasciculation and elongation protein zeta-1 [Panthera tigris altaica]
ENSG00000149571(KIRREL3)	--	4.158198	314	3.744748	270	4.926888	372	5.77254	427	7.6949	556	5.76593	421	0.729665733	0.410909287	normal	1.30E-05	1.016648279	up	0.954242026	0.169577775	normal	0.032967638	0.533855377	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Kin of IRRE-like protein 3 (Precursor) GN=UNQ5923/PRO4502/PRO19814 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: kin of IRRE-like protein 3 isoform X4 [Mustela putorius furo] 
ENSG00000149573(MPZL2)	--	0	0	0.056683	2	0	0	0.0837101	3	0.081745662	2	0.083764247	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain	Myelin protein zero-like protein 2 (Precursor) GN=MPZL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: myelin protein zero-like protein 2 [Ceratotherium simum simum]
ENSG00000149575(SCN2B)	--	0	0	0	0	0	0	0.00860438	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04846|5.59175e-126|nle:100579973|SCN2B; sodium channel, voltage-gated, type II, beta subunit; K04846 voltage-gated sodium channel type II beta (A)"	--	--	--	Immunoglobulin V-set domain	Sodium channel subunit beta-2 (Precursor) GN=SCN2B OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	sodium channel subunit beta-2 precursor [Canis lupus familiaris] 
ENSG00000149577(SIDT2)	--	4.971507226	381	4.27723213	299	3.813008503	287	4.251309132	322	4.938196784	361	3.030481639	226	0.91441795	-0.272366082	normal	0.926747856	0.249277959	normal	0.860405589	-0.350930452	normal	0.815844107	-0.111486429	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: dsRNA transport (GO:0033227);; Molecular Function: RNA transmembrane transporter activity (GO:0051033);; 	--	--	--	--	dsRNA-gated channel SID-1	SID1 transmembrane family member 2 (Precursor) GN=SIDT2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: SID1 transmembrane family member 2 isoform X2 [Mustela putorius furo]
ENSG00000149582(TMEM25)	--	0.561412073	9	0.30000443	9	0.4129077	18	0.320195836	11	0.318725767	10	0.407396096	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CD80-like C2-set immunoglobulin domain	Transmembrane protein 25 (Precursor) GN=TMEM25 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 25 isoform X2 [Felis catus] 
ENSG00000149591(TAGLN)	--	2.566294	65	3.845456	83	3.32078	76	33.180093	546	48.571626	747	13.649801	226	0	3.01030466	up	0	3.125579743	up	1.58E-08	1.545264518	up	0.005959918	2.738786908	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Calponin homology (CH) domain;; Calponin family repeat	Transgelin GN=TAGLN OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: transgelin [Loxodonta africana]
ENSG00000149596(JPH2)	--	1.432218	142	1.9757186	181	2.209503317	169	2.378757	219	3.137386851	286	3.732900567	302	0.415164298	0.58904003	normal	0.193796159	0.634348573	normal	0.008553155	0.823645197	normal	0.00584275	0.693747343	normal	--	--	--	--	--	[R]	General function prediction only	MORN repeat	Junctophilin-2 GN=JPH2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: junctophilin-2 [Ochotona princeps]
ENSG00000149599(DUSP15)	--	1.341845269	19	1.401384576	21	0.653532905	11	0.382620862	6	1.664653969	30	0.861856681	14	--	--	--	0.974017697	0.465009098	normal	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14165|5.70569e-97|pps:100976568|DUSP15; dual specificity phosphatase 15; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Inositol hexakisphosphate;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 15 GN=DUSP15 OS=Homo sapiens (Human) PE=1 SV=4	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 15 isoform 2 [Trichechus manatus latirostris]
ENSG00000149600(COMMD7)	--	32.18276	918	38.04187022	1165	34.03732	941	32.55054185	964	34.724172	1000	38.862338	1144	0.978237029	0.039641984	normal	0.944843702	-0.241417874	normal	0.925559015	0.273130285	normal	0.960928484	0.018618807	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 7 GN=COMMD7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: COMM domain-containing protein 7 [Orcinus orca] 
ENSG00000149609(C20orf144)	--	0.156011	1	0	0	0.290893	1	0	0	0.30131	1	0.304008	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative Bcl-2 like protein of testis	Uncharacterized protein C20orf144 GN=C20orf144 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C20orf144-like [Lipotes vexillifer]
ENSG00000149633(KIAA1755)	--	0.022081653	3	0.007294322	1	0.021480563	2	0.04102368	4	0.021529627	2	0.036507122	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Divergent CRAL/TRIO domain	Uncharacterized protein KIAA1755 GN=KIAA1755 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	"PREDICTED: uncharacterized protein KIAA1755 homolog, partial [Galeopterus variegatus]"
ENSG00000149634(SPATA25)	--	0.780444642	32	0.688228373	29	0.862933	28	0.532305303	22	0.946812	32	0.866218813	36	0.967853767	-0.539952536	normal	0.983047702	0.11488769	normal	0.976639589	0.338135615	normal	1	-0.003719555	normal	--	--	--	--	--	--	--	Spermatogenesis-associated protein 25	Spermatogenesis-associated protein 25 GN=SPATA25 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: spermatogenesis-associated protein 25 [Tupaia chinensis] 
ENSG00000149636(DSN1)	--	19.43364501	706	19.64453453	735	21.14159262	781	17.76013783	663	15.56102288	601	17.464226	619	0.968233024	-0.12121928	normal	0.883616534	-0.311096601	normal	0.840518952	-0.342926953	normal	0.194014419	-0.260118349	normal	--	--	Cellular Component: MIS12/MIND type complex (GO:0000444);; Biological Process: chromosome segregation (GO:0007059);; Biological Process: cell division (GO:0051301);; 	"K11544|0|hsa:79980|DSN1, C20orf172, KNL3, MIS13, dJ469A13.2, hKNL-3; DSN1, MIS12 kinetochore complex component; K11544 kinetochore-associated protein DSN1 (A)"	--	--	--	Mis12-Mtw1 protein family	Kinetochore-associated protein DSN1 homolog GN=DSN1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: kinetochore-associated protein DSN1 homolog isoform X1 [Galeopterus variegatus]
ENSG00000149639(SOGA1)	--	8.474349	2458	9.1584104	2669	9.101892772	2673	6.931727	1996	7.236212511	2087	6.8599552	1976	0.900672594	-0.330975379	normal	0.840535742	-0.376053624	normal	0.618862858	-0.4438751	normal	0.011690098	-0.385526018	normal	--	--	Cellular Component: extracellular space (GO:0005615);; Biological Process: regulation of autophagy (GO:0010506);; 	--	--	--	--	Protein of unknown function (DUF3166);; Domain of unknown function (DUF4482)	C-terminal 80 kDa form GN=SOGA1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein SOGA1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000149646(CNBD2)	--	2.5024482	20	2.428838998	23	5.3855101	40	4.4208402	33	2.77074	19	3.151146162	24	0.955298476	0.652292185	normal	0.985134297	-0.276992549	normal	0.918935843	-0.710240831	normal	0.892992905	-0.148394815	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Cyclic nucleotide-binding domain	Cyclic nucleotide-binding domain-containing protein 2 GN=CNBD2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: cyclic nucleotide-binding domain-containing protein 2-like [Ceratotherium simum simum]
ENSG00000149654(CDH22)	--	0.028832491	2	0	0	0.013600877	0	0.028523896	2	0.055343929	3	0.042323288	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06812|0|hsa:64405|CDH22, C20orf25, dJ998H6.1; cadherin 22, type 2; K06812 cadherin 22 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-22 (Precursor) GN=CDH22 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: cadherin-22 [Odobenus rosmarus divergens]
ENSG00000149657(LSM14B)	--	15.58915601	766	17.39608766	958	15.88973355	809	15.6060383	787	15.59020514	809	17.18113093	916	0.976567836	0.008170812	normal	0.927515748	-0.264856908	normal	0.963320931	0.170616548	normal	0.912431504	-0.032909831	normal	--	--	--	"K18749|0|hsa:149986|LSM14B, C20orf40, FAM61B, LSM13, RAP55B, bA11M20.3; LSM14B, SCD6 homolog B (S. cerevisiae); K18749 protein LSM14 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Scd6-like Sm domain;; FDF domain;; Ataxin 2 SM domain	Protein LSM14 homolog B GN=LSM14B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein LSM14 homolog B [Oryctolagus cuniculus]
ENSG00000149658(YTHDF1)	--	29.66697	1575	30.55845	1710	27.15000257	1516	39.56697	2236	43.724156	2448	38.73997	2142	0.463658075	0.474345996	normal	0.399703761	0.4958124	normal	0.389669003	0.489984103	normal	0.000863638	0.486292171	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	--	--	[R]	General function prediction only	YT521-B-like domain	YTH domain-containing family protein 1 GN=YTHDF1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: YTH domain-containing family protein 1 [Eptesicus fuscus]
ENSG00000149679(CABLES2)	--	8.59612105	641	6.649166812	492	8.425860621	628	5.913515517	436	5.871359951	437	5.563727	416	0.124324254	-0.585116325	normal	0.949059833	-0.191825519	normal	0.100000293	-0.600682346	normal	0.01307248	-0.471215912	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	CDK5 and ABL1 enzyme substrate 2 GN=CABLES2 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: LOW QUALITY PROTEIN: CDK5 and ABL1 enzyme substrate 2 [Canis lupus familiaris]
ENSG00000149716(ORAOV1)	--	17.79099272	452	17.57728302	462	19.6009569	481	18.663422	477	17.55760924	496	13.99381334	420	0.970035786	0.046679768	normal	0.967597299	0.080765533	normal	0.946105526	-0.203254569	normal	0.95613985	-0.023490786	normal	--	--	--	--	--	[S]	Function unknown	"Essential protein Yae1, N terminal"	Oral cancer-overexpressed protein 1 GN=ORAOV1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	"Oral cancer-overexpressed protein 1, partial [Tupaia chinensis]"
ENSG00000149743(TRPT1)	--	18.0807252	225	15.125974	198	15.31249	198	16.84117846	202	14.1276479	165	15.94267103	194	0.951293233	-0.185067337	normal	0.923415413	-0.282097012	normal	0.966517035	-0.037446272	normal	0.668074155	-0.168084965	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Biological Process: tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388);; Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	K10669|1.98176e-169|hsa:83707|TRPT1; tRNA phosphotransferase 1 (EC:2.7.1.160); K10669 2'-phosphotransferase [EC:2.7.1.160] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	"RNA 2'-phosphotransferase, Tpt1 / KptA family"	tRNA 2'-phosphotransferase 1 GN=TRPT1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA 2'-phosphotransferase 1 isoform X1 [Vicugna pacos]
ENSG00000149781(FERMT3)	--	0.385319218	9	0.525535	7	1.194487	32	0.433242148	13	0.897311	18	0.073457	1	--	--	--	--	--	--	2.06E-05	-3.743227073	down	--	--	--	--	--	--	K17084|0|pps:100984520|FERMT3; fermitin family member 3; K17084 kindlin 3 (A)	Platelet activation (ko04611)	[D]	"Cell cycle control, cell division, chromosome partitioning"	FERM central domain;; PH domain	Fermitin family homolog 3 GN=FERMT3 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: fermitin family homolog 3 isoform X2 [Galeopterus variegatus]
ENSG00000149782(PLCB3)	--	13.12188	1236	9.985875	961	12.857407	1246	15.52784	1470	14.446096	1361	10.14897121	968	0.958360086	0.219055226	normal	0.440039639	0.479994541	normal	0.796011056	-0.372002887	normal	0.76783972	0.11989336	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: lipid catabolic process (GO:0016042);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05858|0|hsa:5331|PLCB3; phospholipase C, beta 3 (phosphatidylinositol-specific) (EC:3.1.4.11); K05858 phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Chemokine signaling pathway (ko04062);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Huntington's disease (ko05016);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Pathways in cancer (ko05200)	[I]	Lipid transport and metabolism	"PLC-beta C terminal;; Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain;; Protein of unknown function (DUF1154)"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 GN=PLCB3 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 isoform 1 [Odobenus rosmarus divergens] "
ENSG00000149792(MRPL49)	--	32.7621	1202	39.0717	1267	34.40335	1232	31.391046	1120	34.290531	1199	43.800619	1464	0.974127242	-0.132594789	normal	0.977796277	-0.100887615	normal	0.950333513	0.240350896	normal	0.977607604	0.011213007	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K17430|1.53581e-119|hsa:740|MRPL49, C11orf4, L49mt, MRP-L49, NOF, NOF1; mitochondrial ribosomal protein L49; K17430 large subunit ribosomal protein L49 (A)"	--	[S]	Function unknown	Mitochondrial large subunit ribosomal protein (Img2)	"39S ribosomal protein L49, mitochondrial GN=MRPL49 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L49, mitochondrial [Ceratotherium simum simum]"
ENSG00000149806(FAU)	--	320.3804947	3022	339.816906	3255	321.954059	3165	396.7518324	3797	374.7415974	3565	318.9358742	3095	0.947188253	0.298388497	normal	0.988407173	0.109769233	normal	0.990212033	-0.040537944	normal	0.550000738	0.125521086	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02983|8.6964e-75|ptr:466658|FAU; Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed; K02983 small subunit ribosomal protein S30e (A)	Ribosome (ko03010)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ribosomal protein S30;; Ubiquitin family	Ubiquitin-like protein FUBI GN=FAU OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	ubiquitin-like protein FUBI precursor [Sus scrofa] 
ENSG00000149809(TM7SF2)	--	68.90013585	2077	60.63840434	1765	61.91667082	1898	39.59860091	1322	51.37502096	1645	53.24024714	1778	0.007981116	-0.681973081	normal	0.980088521	-0.122898052	normal	0.982959335	-0.102431768	normal	0.117482743	-0.294903981	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K00222|0|ggo:101135476|TM7SF2; delta(14)-sterol reductase isoform 1; K00222 delta14-sterol reductase [EC:1.3.1.70] (A)	Steroid biosynthesis (ko00100)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Ergosterol biosynthesis ERG4/ERG24 family;; Protein of unknown function (DUF1295)	Delta(14)-sterol reductase GN=TM7SF2 OS=Homo sapiens (Human) PE=2 SV=3	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: delta(14)-sterol reductase isoform X1 [Orycteropus afer afer]
ENSG00000149922(TBX6)	--	0.4650779	16	0.611752	20	0.306003065	10	0.2640499	9	0.5407522	19	0.71584109	25	--	--	--	0.988135588	-0.088556171	normal	0.855819862	1.195976258	normal	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10180|0|hsa:6911|TBX6, SCDO5; T-box 6; K10180 T-box protein 6 (A)"	--	[K]	Transcription	T-box	T-box transcription factor TBX6 GN=TBX6 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: T-box transcription factor TBX6 [Felis catus] 
ENSG00000149923(PPP4C)	--	70.680428	1778	78.1880037	2010	82.86765485	2151	84.637529	2155	83.89825137	2112	75.06392302	1930	0.957009985	0.246406643	normal	0.986166049	0.049951111	normal	0.978042945	-0.164575901	normal	0.883493494	0.040057003	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K15423|0|umr:103657830|PPP4C; protein phosphatase 4, catalytic subunit; K15423 serine/threonine-protein phosphatase 4 catalytic subunit [EC:3.1.3.16] (A)"	--	[GT]	Carbohydrate transport and metabolism;; Signal transduction mechanisms	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase 4 catalytic subunit GN=PPP4C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"Serine/threonine-protein phosphatase 4 catalytic subunit, partial [Bos mutus]"
ENSG00000149925(ALDOA)	--	1471.888518	37206	1381.777954	35947	1403.887799	36011	1194.914413	31967	820.849429	21084	1213.12745	31941	0.995034989	-0.249773059	normal	0.001531898	-0.791105332	normal	0.997277566	-0.181311534	normal	0.074502177	-0.382497102	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: fructose-bisphosphate aldolase activity (GO:0004332);; Biological Process: glycolytic process (GO:0006096);; 	"K01623|0|cjc:100394290|ALDOA; aldolase A, fructose-bisphosphate; K01623 fructose-bisphosphate aldolase, class I [EC:4.1.2.13] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Fructose-bisphosphate aldolase class-I	Fructose-bisphosphate aldolase A GN=ALDOA OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: fructose-bisphosphate aldolase A isoform X1 [Ochotona princeps]
ENSG00000149926(FAM57B)	--	0.928444966	32	0.35590576	14	0.8018213	30	0.251065729	6	0.2498272	8	0.189674835	8	0.017846112	-2.180754971	normal	--	--	--	0.209873682	-1.735483672	normal	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	TLC domain	Protein FAM57B GN=FAM57B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein FAM57B isoform X2 [Mustela putorius furo]
ENSG00000149927(DOC2A)	--	3.091328548	115	2.56764	94	2.823439709	104	1.995764315	73	2.519611629	92	2.405986054	88	0.53932914	-0.675074311	normal	0.969702509	-0.051614077	normal	0.955196261	-0.245415356	normal	0.492074617	-0.32756496	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Double C2-like domain-containing protein alpha GN=DOC2A OS=Homo sapiens (Human) PE=1 SV=5	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: double C2-like domains, alpha isoform X1 [Canis lupus familiaris]"
ENSG00000149929(HIRIP3)	--	5.71635	287	5.5538	247	5.55097	277	9.4928628	400	7.72144	361	7.92095	353	0.648712825	0.446086146	normal	0.438474454	0.523396033	normal	0.861009783	0.339843407	normal	0.061593315	0.436480531	normal	--	--	--	--	--	--	--	Histone chaperone domain CHZ	HIRA-interacting protein 3 GN=HIRIP3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: HIRA-interacting protein 3 [Galeopterus variegatus]
ENSG00000149930(TAOK2)	--	20.7823028	2198	19.936081	2165	19.806818	2175	19.53379105	2055	20.96965832	2192	19.55217537	2065	0.982675618	-0.127792843	normal	0.987312605	-0.003543325	normal	0.98558126	-0.083105751	normal	0.764061674	-0.071893154	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04429|0|ptr:454033|TAOK2; TAO kinase 2; K04429 thousand and one amino acid protein kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase TAO2 GN=UNQ2971/PRO7431 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase TAO2 isoform 1 [Dasypus novemcinctus]
ENSG00000149932(TMEM219)	--	46.66988459	775	38.24947148	640	49.0528831	769	41.73722442	684	44.09827616	731	40.29857795	675	0.949263882	-0.210587473	normal	0.95942198	0.169996875	normal	0.954039235	-0.195975863	normal	0.754018971	-0.084467048	normal	--	--	--	--	--	--	--	Transmembrane 219	Insulin-like growth factor-binding protein 3 receptor (Precursor) GN=TMEM219 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: insulin-like growth factor-binding protein 3 receptor isoform X4 [Ursus maritimus]
ENSG00000149948(HMGA2)	--	34.8811354	2118	34.668907	2135	41.42985945	2384	76.851252	4583	43.5517251	2569	40.770288	2399	7.44E-09	1.082211158	up	0.962127596	0.245385622	normal	0.988452046	0.000757001	normal	0.384341351	0.501900678	normal	--	--	--	--	--	--	--	Putative binding domain;; AT hook motif	Putative uncharacterized protein encoded by LINC00596 GN=LINC00596 OS=Homo sapiens (Human) PE=5 SV=1	K	Transcription	PREDICTED: high mobility group protein HMGI-C [Bos mutus]
ENSG00000149970(CNKSR2)	--	2.670650272	283	3.03710192	330	2.891379383	308	2.742461929	294	3.12607496	336	2.126324314	228	0.967380286	0.024053717	normal	0.967482678	0.004547996	normal	0.709541178	-0.439669159	normal	0.72050378	-0.124006186	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	K17536|0|ggo:101133794|CNKSR2; connector enhancer of kinase suppressor of ras 2 isoform 1; K17536 connector enhancer of kinase suppressor of Ras 2 (A)	--	[F]	Nucleotide transport and metabolism	Protein of unknown function (DUF1170);; Connector enhancer of kinase suppressor of ras;; SAM domain (Sterile alpha motif);; PH domain;; SAM domain (Sterile alpha motif);; PDZ domain (Also known as DHR or GLGF)	Connector enhancer of kinase suppressor of ras 2 GN=CNKSR2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: connector enhancer of kinase suppressor of ras 2 isoform X1 [Pteropus alecto]
ENSG00000149972(CNTN5)	--	0	0	0.013390102	1	0	0	0.026955788	2	0.052508101	3	0.013428888	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06763|0|hsa:53942|CNTN5, HNB-2s, NB-2; contactin 5; K06763 contactin 5 (A)"	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Tissue factor;; Immunoglobulin C2-set domain	Contactin-5 (Precursor) GN=CNTN5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: contactin-5 [Sus scrofa]
ENSG00000150045(KLRF1)	--	0	0	0	0	0	0	0.099186395	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10075|1.38176e-158|pps:100969720|KLRF1; killer cell lectin-like receptor subfamily F, member 1; K10075 killer cell lectin-like receptor subfamily F member 1 (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	Killer cell lectin-like receptor subfamily F member 1 GN=KLRF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: killer cell lectin-like receptor subfamily F member 1 [Ceratotherium simum simum]
ENSG00000150051(MKX)	--	0	0	0	0	0	0	0	0	0	0	0.036819983	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein Mohawk GN=MKX OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein Mohawk isoform X1 [Equus przewalskii] 
ENSG00000150054(MPP7)	--	0.227239611	18	0.356093218	24	0.23952606	15	0.076302536	4	0.118784715	7	0.122556949	6	--	--	--	0.57365288	-1.602462529	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Guanylate kinase;; L27 domain;; PDZ domain (Also known as DHR or GLGF);; Variant SH3 domain;; SH3 domain	MAGUK p55 subfamily member 7 GN=MPP7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: MAGUK p55 subfamily member 7 isoform X1 [Felis catus]
ENSG00000150093(ITGB1)	--	819.4392656	52514	777.480734	50711	744.985914	47277	1114.312727	72079	988.0657195	63523	886.5256748	56416	0.962384699	0.426033964	normal	0.993831724	0.303545664	normal	0.996529894	0.246667215	normal	0.146082858	0.329373668	normal	--	--	--	"K05719|0|ptr:450396|ITGB1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); K05719 integrin beta 1 (A)"	Rap1 signaling pathway (ko04015);; Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Cell adhesion molecules (CAMs) (ko04514);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Small cell lung cancer (ko05222);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; Integrin beta tail domain;; Integrin beta cytoplasmic domain;; EGF-like domain"	Integrin beta-1 (Precursor) GN=ITGB1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin beta-1 isoform X1 [Leptonychotes weddellii]
ENSG00000150275(PCDH15)	--	0	0	0	0	0	0	0	0	0.054383119	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16500|0|hsa:65217|PCDH15, CDHR15, DFNB23, USH1F; protocadherin-related 15; K16500 protocadherin-15 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin-15 (Precursor) GN=PCDH15 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protocadherin-15-like isoform X1 [Tupaia chinensis]
ENSG00000150281(CTF1)	--	0.447718547	8	0	0	0	0	0.278481975	5	0.215236073	3	0.330577973	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05422|3.55724e-70|hsa:1489|CTF1, CT-1, CT1; cardiotrophin 1; K05422 cardiotrophin 1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	--	Cardiotrophin-1 GN=CTF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	cardiotrophin-1 [Canis lupus familiaris]
ENSG00000150316(CWC15)	--	13.0327085	363	12.303685	342	11.163969	307	14.94146416	422	15.3596747	422	13.67888	384	0.95012271	0.185711677	normal	0.908204123	0.280700981	normal	0.884573132	0.313194035	normal	0.310352794	0.257427822	normal	--	--	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Cellular Component: spliceosomal complex (GO:0005681);; "	K12863|1.80755e-93|cfr:102519889|CWC15; CWC15 spliceosome-associated protein homolog (S. cerevisiae); K12863 protein CWC15 (A)	Spliceosome (ko03040)	[S]	Function unknown	Cwf15/Cwc15 cell cycle control protein	Spliceosome-associated protein CWC15 homolog GN=CWC15 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: spliceosome-associated protein CWC15 homolog isoform X1 [Camelus ferus] 
ENSG00000150337(FCGR1A)	--	0.172261001	6	0.4051945	5	0.142914052	4	0.0571172	2	0.027822262	0	0.141984	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06498|0|hsa:2209|FCGR1A, CD64, CD64A, FCRI, IGFR1; Fc fragment of IgG, high affinity Ia, receptor (CD64); K06498 high affinity immunoglobulin gamma Fc receptor I (A)"	Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Hematopoietic cell lineage (ko04640);; Fc gamma R-mediated phagocytosis (ko04666);; Leishmaniasis (ko05140);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain	High affinity immunoglobulin gamma Fc receptor I (Precursor) GN=FCGR1A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: high affinity immunoglobulin gamma Fc receptor I-like [Ceratotherium simum simum]
ENSG00000150347(ARID5B)	--	1.603814299	255	1.569126032	232	1.496736	227	1.33781772	205	1.26661495	196	2.471241241	380	0.874568529	-0.343392627	normal	0.926915806	-0.262831207	normal	0.023329922	0.731210204	normal	0.892992905	0.109978397	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	ARID/BRIGHT DNA binding domain	AT-rich interactive domain-containing protein 5B GN=ARID5B OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 5B isoform X1 [Equus caballus] 
ENSG00000150394(CDH8)	--	0.081061074	6	0.039116965	1	0.014641186	0	0.11723231	8	0.15992906	4	0.238237091	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06800|0|ptr:454141|CDH8; cadherin 8, type 2; K06800 cadherin 8, type 2 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Cadherin-8 (Precursor) GN=CDH8 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cadherin-8 [Equus caballus]
ENSG00000150401(DCUN1D2)	--	3.650360023	148	6.441894875	185	3.84981533	135	2.989566	144	5.474142295	177	4.374453056	164	0.966555964	-0.069627778	normal	0.963325547	-0.084496232	normal	0.936197215	0.269699873	normal	0.964739885	0.030329303	normal	--	--	--	"K17822|0|hsa:55208|DCUN1D2, C13orf17; DCN1, defective in cullin neddylation 1, domain containing 2; K17822 DCN1-like protein 1/2 (A)"	--	[S]	Function unknown	Cullin binding;; UBA-like domain	DCN1-like protein 2 GN=DCUN1D2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DCN1-like protein 2 [Eptesicus fuscus]
ENSG00000150403(TMCO3)	--	25.22796252	1307	24.59977081	1363	21.6242878	1155	26.70398033	1339	24.28270231	1282	20.364879	1086	0.982699443	0.004059841	normal	0.977973695	-0.109690341	normal	0.977331023	-0.097029148	normal	0.792609278	-0.06725179	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Transmembrane and coiled-coil domain-containing protein 3 (Precursor) GN=TMCO3 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: transmembrane and coiled-coil domain-containing protein 3 isoform X1 [Myotis brandtii] 
ENSG00000150433(TMEM218)	--	15.7615859	260	17.361875	308	18.99747212	277	13.9664085	227	12.30760554	224	15.51330287	273	0.939701855	-0.22522578	normal	0.615515119	-0.478093008	normal	0.96714821	-0.029116343	normal	0.418417897	-0.243697763	normal	--	--	--	--	--	--	--	--	Transmembrane protein 218 GN=TMEM218 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 218 [Loxodonta africana]
ENSG00000150455(TIRAP)	--	3.180620905	230	3.507311376	233	4.282736087	228	2.334869418	187	2.793287228	182	3.81379909	238	0.893768488	-0.327000157	normal	0.850203161	-0.375056036	normal	0.965932561	0.053290328	normal	0.55303736	-0.207508708	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K05403|4.84239e-133|ptr:451654|TIRAP; toll-interleukin 1 receptor (TIR) domain containing adaptor protein; K05403 toll-interleukin 1 receptor (TIR) domain-containing adaptor protein (A)	NF-kappa B signaling pathway (ko04064);; Toll-like receptor signaling pathway (ko04620);; Pertussis (ko05133);; Tuberculosis (ko05152);; Hepatitis B (ko05161)	--	--	TIR domain;; TIR domain	Toll/interleukin-1 receptor domain-containing adapter protein GN=TIRAP OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: toll/interleukin-1 receptor domain-containing adapter protein [Ceratotherium simum simum]
ENSG00000150456(EEF1AKMT1)	--	2.438575239	46	2.196361232	42	3.307061	58	4.354522036	89	3.633446952	66	2.883200753	53	0.270311474	0.899391817	normal	0.865127402	0.612912991	normal	0.975329941	-0.134677192	normal	0.358143367	0.488339431	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[S]	Function unknown	Probable N6-adenine methyltransferase	N(6)-adenine-specific DNA methyltransferase 2 GN=N6AMT2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: N(6)-adenine-specific DNA methyltransferase 2 isoform X1 [Equus caballus] 
ENSG00000150457(LATS2)	--	4.94849	523	7.63388	807	6.69207	711	4.62929	488	4.67332	493	6.40521	679	0.963369431	-0.130365463	normal	0.006158603	-0.730637085	normal	0.973004882	-0.074567112	normal	0.417583443	-0.318271142	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08791|0|hsa:26524|LATS2, KPM; large tumor suppressor kinase 2 (EC:2.7.11.1); K08791 serine/threonine-protein kinase LATS1/2 [EC:2.7.11.1] (A)"	Hippo signaling pathway (ko04390)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Protein kinase C terminal domain	Serine/threonine-protein kinase LATS2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase LATS2 [Tupaia chinensis]
ENSG00000150459(SAP18)	--	38.364704	1320	39.12009	1369	33.99056	1380	36.12577813	1489	34.1380392	1361	36.2055	1418	0.975540812	0.142816985	normal	0.98235865	-0.029848868	normal	0.9830451	0.030864456	normal	0.859501689	0.047555724	normal	--	--	--	"K14324|4.90679e-115|pps:100976455|SAP18; Sin3A-associated protein, 18kDa; K14324 histone deacetylase complex subunit SAP18 (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[K]	Transcription	Sin3 associated polypeptide p18 (SAP18)	Histone deacetylase complex subunit SAP18 GN=SAP18 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone deacetylase complex subunit SAP18 [Ochotona princeps]
ENSG00000150471(ADGRL3)	--	0	0	0	0	0	0	0.159928886	31	0.347680983	46	0.425012606	44	5.92E-06	4.38975142	up	7.12E-10	4.963161324	up	1.87E-09	4.90744873	up	3.33E-15	Inf	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: carbohydrate binding (GO:0030246);; 	K04594|0|cfa:482166|LPHN3; latrophilin-3-like; K04594 latrophilin 3 (A)	--	[T]	Signal transduction mechanisms	Latrophilin Cytoplasmic C-terminal region;; Olfactomedin-like domain;; Domain of unknown function (DUF3497);; 7 transmembrane receptor (Secretin family);; Galactose binding lectin domain;; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain	Latrophilin-3 (Precursor) GN=LPHN3 OS=Homo sapiens (Human) PE=1 SV=2	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: latrophilin-3-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000150477(KIAA1328)	--	2.1901503	94	2.142103	73	2.186513504	100	2.4430464	113	1.805711135	78	1.638282591	77	0.955774389	0.231306006	normal	0.971668312	0.072694102	normal	0.925122564	-0.378813827	normal	0.989936683	-0.016736607	normal	--	--	--	--	--	--	--	Uncharacterised protein KIAA1328	Uncharacterized protein KIAA1328 GN=KIAA1328 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA1328-like [Tupaia chinensis]
ENSG00000150510(FAM124A)	--	1.901779596	123	1.406610526	82	1.779749806	98	1.290062334	84	1.923883905	118	1.273663483	76	0.712181978	-0.572321844	normal	0.82889725	0.496001562	normal	0.929980536	-0.368597199	normal	0.804402757	-0.145471709	normal	--	--	--	--	--	--	--	FAM124 family	Protein FAM124A GN=FAM124A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM124A isoform X1 [Tupaia chinensis] 
ENSG00000150526(MIA2)	--	14.12007504	860	13.09467184	795	12.5474729	749	14.53412563	893	15.00881258	957	18.02257504	1049	0.977796042	0.023450139	normal	0.937991841	0.245710993	normal	0.433576951	0.476868319	normal	0.185879883	0.249261565	normal	--	--	--	--	--	--	--	Variant SH3 domain	Melanoma inhibitory activity protein 2 (Precursor) GN=MIA2 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: melanoma inhibitory activity protein 2 [Ceratotherium simum simum]
ENSG00000150540(HNMT)	--	0	0	0.055125609	1	0.054644117	0	0.475638059	19	1.422346377	34	1.488461575	32	--	--	--	8.53E-06	3.806736254	up	2.37E-06	4.46593213	up	--	--	--	--	--	--	K00546|0|ptr:742204|HNMT; histamine N-methyltransferase; K00546 histamine N-methyltransferase [EC:2.1.1.8] (A)	Histidine metabolism (ko00340)	--	--	Methyltransferase domain;; Methyltransferase domain	Histamine N-methyltransferase GN=HNMT OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: histamine N-methyltransferase [Ceratotherium simum simum]
ENSG00000150551(LYPD1)	--	13.115284	412	9.337252011	299	12.13236	396	26.41609	822	27.59657239	877	22.07856	704	1.04E-05	0.963071731	normal	2.36E-14	1.526284272	up	0.000783678	0.819404968	normal	3.25E-11	1.096878232	up	--	--	--	--	--	--	--	--	Ly6/PLAUR domain-containing protein 1 (Precursor) GN=LYPD1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ly6/PLAUR domain-containing protein 1-like [Tupaia chinensis]
ENSG00000150556(LYPD6B)	--	0.114369064	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Ly6/PLAUR domain-containing protein 6B (Precursor) GN=LYPD6B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: ly6/PLAUR domain-containing protein 6B [Ceratotherium simum simum]
ENSG00000150593(PDCD4)	--	9.966001012	477	8.884092442	498	10.45604235	515	14.38580384	736	15.00303109	705	19.48285	978	0.09931109	0.593334848	normal	0.470827275	0.47882329	normal	2.66E-05	0.914988016	normal	0.004875718	0.678827069	normal	--	--	--	K16865|0|ptr:450735|PDCD4; programmed cell death 4 (neoplastic transformation inhibitor); K16865 programmed cell death protein 4 (A)	Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	MA3 domain	Programmed cell death protein 4 GN=PDCD4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: programmed cell death protein 4 isoform X1 [Canis lupus familiaris] 
ENSG00000150594(ADRA2A)	--	0.0188335	1	0	0	0.0359105	1	0	0	0.0541766	2	0.0184628	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04138|0|pon:100459426|ADRA2A; adrenoceptor alpha 2A; K04138 adrenergic receptor alpha-2A (A)	cGMP-PKG signaling pathway (ko04022);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Alpha-2A adrenergic receptor GN=ADRA2A OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: alpha-2A adrenergic receptor [Chrysochloris asiatica]
ENSG00000150625(GPM6A)	--	0.087893191	3	0.029308716	1	0	0	0.753781318	7	0.353110655	5	0.02854037	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[X]	--	Myelin proteolipid protein (PLP or lipophilin)	Neuronal membrane glycoprotein M6-a GN=GPM6A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: neuronal membrane glycoprotein M6-a [Erinaceus europaeus]
ENSG00000150627(WDR17)	--	3.309345139	357	2.992654753	321	2.8969715	329	1.72841175	190	1.624713458	178	1.563976865	170	0.00043932	-0.935143267	normal	0.003316379	-0.866557592	normal	0.00044064	-0.954627885	normal	2.55E-05	-0.925947336	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 17 GN=WDR17 OS=Homo sapiens (Human) PE=2 SV=2	B	Chromatin structure and dynamics	PREDICTED: WD repeat-containing protein 17 isoform 1 [Ceratotherium simum simum]
ENSG00000150628(SPATA4)	--	0.315526194	5	0.272107	6	0.1882535	3	0.311433482	5	0.091320835	2	0.124447036	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of Unknown Function (DUF1042);; CAMSAP CH domain	Spermatogenesis-associated protein 4 GN=SPATA4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: spermatogenesis-associated protein 4 isoform X1 [Equus przewalskii] 
ENSG00000150630(VEGFC)	--	11.904195	487	11.691357	477	11.363649	466	10.477015	427	9.465547	386	10.755487	440	0.94016658	-0.219776783	normal	0.867508867	-0.325664805	normal	0.96704218	-0.090814526	normal	0.394800122	-0.211830466	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	"K05449|0|hsa:7424|VEGFC, Flt4-L, LMPH1D, VRP; vascular endothelial growth factor C; K05449 vascular endothelial growth factor C/D (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; TNF signaling pathway (ko04668);; Pathways in cancer (ko05200)	--	--	PDGF/VEGF domain;; CXCXC repeat	Vascular endothelial growth factor C (Precursor) GN=VEGFC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vascular endothelial growth factor C-like [Tupaia chinensis]
ENSG00000150636(CCDC102B)	--	0.25241085	3	0.0907632	2	0.045195994	0	0	0	0.059984255	1	0.03043524	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 102B GN=CCDC102B OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 102B [Ceratotherium simum simum]
ENSG00000150637(CD226)	--	0.206279711	35	0.682253284	19	0.227905355	25	0.19006321	19	0.421588918	20	0.482022201	26	0.892678145	-0.860179688	normal	0.988289644	0.048788958	normal	0.986415772	0.045587858	normal	0.739936328	-0.301676454	normal	--	--	--	"K06567|0|hsa:10666|CD226, DNAM-1, DNAM1, PTA1, TLiSA1; CD226 molecule; K06567 CD226 antigen (A)"	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	CD226 antigen (Precursor) GN=CD226 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: CD226 antigen [Ceratotherium simum simum]
ENSG00000150667(FSIP1)	--	0.757348325	42	1.239791654	66	0.862046842	34	0.51912884	29	0.69567633	36	0.753393624	36	0.952075393	-0.541203676	normal	0.550351831	-0.86854155	normal	0.982766211	0.071097181	normal	0.409287254	-0.512895658	normal	--	--	--	--	--	--	--	FSIP1 family	Fibrous sheath-interacting protein 1 GN=FSIP1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: fibrous sheath-interacting protein 1 [Pteropus alecto]
ENSG00000150672(DLG2)	--	0.581701	17	0.268488	8	0.268292	7	0.35061647	11	0.200015001	5	0.408939	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12075|0|hsa:1740|DLG2, PPP1R58, PSD-93, PSD93, chapsyn-110; discs, large homolog 2 (Drosophila); K12075 discs large protein 2/3 (A)"	Hippo signaling pathway (ko04390)	[F]	Nucleotide transport and metabolism	PDZ domain (Also known as DHR or GLGF);; Guanylate kinase;; Polyubiquitination (PEST) N-terminal domain of MAGUK;; PDZ-associated domain of NMDA receptors;; PDZ domain;; L27_1;; Variant SH3 domain;; SH3 domain	Disks large homolog 2 GN=DLG2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: disks large homolog 2 isoform X1 [Mustela putorius furo]
ENSG00000150687(PRSS23)	--	109.1949115	6628	119.2705622	7434	130.4248725	7862	201.7834209	12279	168.2561232	10329	170.4659736	10875	5.12E-05	0.858566915	normal	0.77649547	0.452984939	normal	0.74184542	0.459680191	normal	0.00015301	0.589473459	normal	[E]	Amino acid transport and metabolism	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09627|0|ggo:101141579|PRSS23; serine protease 23 isoform 1; K09627 protease, serine, 23 [EC:3.4.21.-] (A)"	--	--	--	Trypsin;; Trypsin-like peptidase domain	Serine protease 23 (Precursor) GN=PRSS23 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine protease 23 [Oryctolagus cuniculus]
ENSG00000150712(MTMR12)	--	11.0927689	968	11.43228771	1010	10.80167807	940	9.640350125	848	8.3706529	727	9.650837175	848	0.949223724	-0.221399236	normal	0.380533472	-0.494876935	normal	0.966664475	-0.156622511	normal	0.109530204	-0.289543826	normal	--	--	--	"K18085|0|hsa:54545|MTMR12, 3-PAP, PIP3AP; myotubularin related protein 12; K18085 myotubularin-related protein 10/11/12 (A)"	--	[R]	General function prediction only	Myotubularin-like phosphatase domain;; Myotubularin-associated protein	Myotubularin-related protein 12 GN=MTMR12 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: myotubularin-related protein 12 isoform 1 [Ceratotherium simum simum]
ENSG00000150722(PPP1R1C)	--	0.913046311	24	0	0	0.274071969	6	1.291886752	32	1.936437804	47	0.67626591	14	0.979012536	0.363973249	normal	4.02E-10	4.993203836	up	--	--	--	0.2150146	1.609124189	normal	--	--	Molecular Function: protein phosphatase inhibitor activity (GO:0004864);; Biological Process: signal transduction (GO:0007165);; 	"K17549|1.35191e-62|mcc:705440|PPP1R1C; protein phosphatase 1, regulatory (inhibitor) subunit 1C; K17549 protein phosphatase 1 regulatory subunit 1C (A)"	--	--	--	Protein phosphatase inhibitor 1/DARPP-32	Protein phosphatase 1 regulatory subunit 1C GN=PPP1R1C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 1C isoform 1 [Trichechus manatus latirostris]
ENSG00000150753(CCT5)	--	139.3233321	6377	130.3444149	6225	146.2631455	6861	157.6419115	7298	148.5443534	6784	115.4342015	5345	0.991048244	0.163754107	normal	0.993164252	0.102611891	normal	0.911128096	-0.368428104	normal	0.940882927	-0.024582383	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09497|0|pps:100979857|CCT5; chaperonin containing TCP1, subunit 5 (epsilon); K09497 T-complex protein 1 subunit epsilon (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit epsilon GN=CCT5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: T-complex protein 1 subunit epsilon isoform X1 [Leptonychotes weddellii]
ENSG00000150756(FAM173B)	--	8.961009371	221	10.41467388	214	10.41208609	247	9.8312881	276	11.43116499	286	11.523552	296	0.912039819	0.287995077	normal	0.806992799	0.394558451	normal	0.928736847	0.251386926	normal	0.273071578	0.310473709	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[S]	Function unknown	Methyltransferase domain	Protein FAM173B GN=FAM173B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM173B [Ceratotherium simum simum]
ENSG00000150760(DOCK1)	--	21.987428	2561	22.08921011	2524	22.77181529	2533	19.2305751	2324	18.02451958	2305	18.22690307	2293	0.979701955	-0.170821807	normal	0.981581292	-0.152276201	normal	0.981870694	-0.151806862	normal	0.412776507	-0.15945336	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13708|0|hsa:1793|DOCK1, DOCK180, ced5; dedicator of cytokinesis 1; K13708 dedicator of cytokinesis protein 1 (A)"	Focal adhesion (ko04510);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Shigellosis (ko05131)	[T]	Signal transduction mechanisms	C2 domain in Dock180 and Zizimin proteins;; Dedicator of cytokinesis;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Dedicator of cytokinesis protein 1 GN=DOCK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dedicator of cytokinesis protein 1 isoform X2 [Bos taurus]
ENSG00000150764(DIXDC1)	--	2.870484497	302	2.430178374	265	2.730573663	285	3.325153511	366	4.454639986	482	2.671271769	292	0.929167634	0.245327752	normal	0.001694367	0.838018238	normal	0.96740073	0.026575689	normal	0.267400513	0.398566029	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	DIX domain;; Calponin homology (CH) domain;; CAMSAP CH domain	Dixin GN=DIXDC1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: dixin isoform 1 [Ceratotherium simum simum]
ENSG00000150768(DLAT)	--	17.1747621	1103	16.90961	1087	18.426227	1209	16.751061	1059	17.240985	1129	16.63241241	1058	0.977387757	-0.089435307	normal	0.979893669	0.033221636	normal	0.960662475	-0.20049775	normal	0.71750797	-0.087419284	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K00627|0|hsa:1737|DLAT, DLTA, PDC-E2, PDCE2; dihydrolipoamide S-acetyltransferase (EC:2.3.1.12); K00627 pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) [EC:2.3.1.12] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	2-oxoacid dehydrogenases acyltransferase (catalytic domain);; Biotin-requiring enzyme;; e3 binding domain;; Biotin-lipoyl like	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (Precursor) GN=DLAT OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	Dixin [Tupaia chinensis]
ENSG00000150773(PIH1D2)	--	0.6287057	13	0.870268547	22	1.1449674	26	0.629851	17	0.614269581	15	0.559465036	13	--	--	--	0.97950944	-0.529631346	normal	0.929617703	-0.930432698	normal	--	--	--	--	--	--	--	--	[S]	Function unknown	pre-RNA processing PIH1/Nop17	PIH1 domain-containing protein 2 GN=PIH1D2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: PIH1 domain-containing protein 2 [Galeopterus variegatus]
ENSG00000150776(C11orf57)	--	7.865480146	503	8.95055621	449	7.52552281	463	10.181512	597	8.093211797	532	8.925023017	554	0.943387621	0.215734849	normal	0.939269092	0.222594813	normal	0.927517261	0.249835404	normal	0.319585114	0.228750439	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf57 GN=C11orf57 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C11orf57 homolog isoform X1 [Tupaia chinensis] 
ENSG00000150779(TIMM8B)	--	28.06070012	320	29.86557705	347	27.60056062	322	31.198319	373	31.98344	365	25.5371	298	0.948688669	0.189428457	normal	0.966789535	0.051316177	normal	0.961394446	-0.119456448	normal	0.908434478	0.04509617	normal	--	--	--	"K17780|1.00955e-66|hsa:26521|TIMM8B, DDP2, TIM8B; translocase of inner mitochondrial membrane 8 homolog B (yeast); K17780 mitochondrial import inner membrane translocase subunit TIM8 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim10/DDP family zinc finger	Mitochondrial import inner membrane translocase subunit Tim8 B GN=TIMM8B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim8 B [Felis catus]
ENSG00000150782(IL18)	--	51.53395	806	58.043749	907	55.37428	861	73.98232	1197	66.87266	1046	89.75048	1433	0.194342442	0.538891311	normal	0.961938475	0.183995976	normal	0.003121289	0.725663607	normal	0.017041342	0.493403979	normal	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular space (GO:0005615);; Biological Process: inflammatory response (GO:0006954);; Biological Process: immune response (GO:0006955);; 	K05482|1.05618e-138|ptr:739011|IL18; interleukin 18; K05482 interleukin 18 (A)	Cytokine-cytokine receptor interaction (ko04060);; NOD-like receptor signaling pathway (ko04621);; Cytosolic DNA-sensing pathway (ko04623);; Salmonella infection (ko05132);; Legionellosis (ko05134);; African trypanosomiasis (ko05143);; Malaria (ko05144);; Tuberculosis (ko05152);; Influenza A (ko05164);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323)	--	--	Interleukin-1 / 18	Interleukin-18 (Precursor) GN=IL18 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-18 isoform X1 [Galeopterus variegatus] 
ENSG00000150783(TEX12)	--	0	0	0	0	0.104142378	0	0.102143111	1	0.10143566	0	0.103517652	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testis-expressed 12	Testis-expressed sequence 12 protein GN=TEX12 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 12 protein [Ochotona princeps]
ENSG00000150787(PTS)	--	15.30417416	203	17.57830222	240	17.59910795	239	19.32500553	265	18.39220386	245	16.80360253	226	0.866222452	0.351347231	normal	0.965991557	0.008269215	normal	0.963863507	-0.088403955	normal	0.831128395	0.088366239	normal	[H]	Coenzyme transport and metabolism	--	"K01737|1.23375e-104|hsa:5805|PTS, PTPS; 6-pyruvoyltetrahydropterin synthase (EC:4.2.3.12); K01737 6-pyruvoyltetrahydropterin/6-carboxytetrahydropterin synthase [EC:4.2.3.12 4.1.2.50] (A)"	Folate biosynthesis (ko00790)	[H]	Coenzyme transport and metabolism	6-pyruvoyl tetrahydropterin synthase	6-pyruvoyl tetrahydrobiopterin synthase GN=PTS OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: 6-pyruvoyl tetrahydrobiopterin synthase [Trichechus manatus latirostris]
ENSG00000150867(PIP4K2A)	--	12.89664149	841	17.57664547	959	14.08719977	781	17.46677337	945	17.53061163	873	17.29828636	825	0.969683692	0.137139828	normal	0.966559	-0.156716579	normal	0.975006801	0.070647017	normal	0.972572149	0.012362387	normal	--	--	Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; 	"K00920|0|aml:100465472|PIP4K2A; phosphatidylinositol-5-phosphate 4-kinase, type II, alpha; K00920 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	Phosphatidylinositol-4-phosphate 5-Kinase	Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha GN=PIP4K2A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 alpha [Ailuropoda melanoleuca]
ENSG00000150873(C2orf50)	--	0.135599068	2	0.23687537	11	0.2460964	6	0	0	0	0	0.0859863	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf50 GN=C2orf50 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C2orf50 homolog [Equus caballus] 
ENSG00000150893(FREM2)	--	0	0	0	0	0	0	0	0	0.0065224	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell communication (GO:0007154);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Calx-beta domain	FRAS1-related extracellular matrix protein 2 (Precursor) GN=FREM2 OS=Homo sapiens (Human) PE=1 SV=2	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: FRAS1-related extracellular matrix protein 2 [Equus caballus]
ENSG00000150907(FOXO1)	--	1.754267587	157	1.842288144	164	1.302917111	115	1.847218576	166	1.856906176	166	1.342149	116	0.96677831	0.049118933	normal	0.966187464	-0.003903356	normal	0.969557356	0.004145227	normal	0.984445003	0.01647571	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K07201|0|ptr:467352|FOXO1, FOXO1A; forkhead box O1; K07201 forkhead box protein O1 (A)"	FoxO signaling pathway (ko04068);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Thyroid hormone signaling pathway (ko04919);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Prostate cancer (ko05215)	[K]	Transcription	Fork head domain	Forkhead box protein O1 GN=FOXO1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: forkhead box protein O1 [Odobenus rosmarus divergens]
ENSG00000150938(CRIM1)	--	116.6262553	12133	133.6295103	14127	126.8161339	13249	76.68469302	8001	58.86173219	6089	105.5412623	10946	0.055270123	-0.631417099	normal	1.37E-11	-1.235396824	down	0.982420572	-0.283735465	normal	0.007405051	-0.678501267	normal	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type C domain;; Antistasin family	Processed cysteine-rich motor neuron 1 protein (Precursor) GN=CRIM1 OS=Homo sapiens (Human) PE=1 SV=1	VW	Defense mechanisms;; Extracellular structures	PREDICTED: cysteine-rich motor neuron 1 protein [Ceratotherium simum simum]
ENSG00000150961(SEC24D)	--	7.200942902	513	7.379542878	520	6.755412	474	9.828834182	721	11.30578477	817	10.187762	715	0.526781811	0.459043615	normal	0.05382347	0.628927129	normal	0.120202593	0.583239316	normal	0.001080054	0.558870197	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: COPII vesicle coat (GO:0030127);; 	K14007|0|hsa:9871|SEC24D; SEC24 family member D; K14007 protein transport protein SEC24 (A)	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec23/Sec24 trunk domain;; Sec23/Sec24 helical domain;; Sec23/Sec24 beta-sandwich domain;; Sec23/Sec24 zinc finger;; Gelsolin repeat	Protein transport protein Sec24D GN=SEC24D OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec24D isoform 1 [Equus caballus]
ENSG00000150967(ABCB9)	--	4.273734	230	3.590685633	222	4.72150961	288	4.516354	265	4.326675	303	4.5611917	292	0.952902639	0.172452387	normal	0.747991789	0.424845426	normal	0.967665119	0.011547894	normal	0.541938217	0.196413807	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05656|0|ptr:452335|ABCB9; ATP-binding cassette, sub-family B (MDR/TAP), member 9; K05656 ATP-binding cassette, subfamily B (MDR/TAP), member 9 (A)"	ABC transporters (ko02010);; Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ABC transporter transmembrane region;; ABC transporter	ATP-binding cassette sub-family B member 9 GN=ABCB9 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ATP-binding cassette sub-family B member 9 isoform X1 [Tupaia chinensis] 
ENSG00000150977(RILPL2)	--	3.347496	235	3.126089	242	3.431775	257	3.754338	268	3.523173662	307	3.877512	277	0.955523033	0.157773593	normal	0.885614799	0.320025864	normal	0.963105226	0.099263443	normal	0.547508785	0.194175399	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	--	--	Rab interacting lysosomal protein	RILP-like protein 2 GN=RILPL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RILP-like protein 2 [Camelus bactrianus]
ENSG00000150990(DHX37)	--	17.018879	1622	17.90734828	1805	17.99984114	1829	17.62371304	1743	20.181641	1991	17.6315092	1727	0.9836155	0.072899867	normal	0.98166413	0.119972095	normal	0.983309661	-0.091000989	normal	0.902498766	0.034154508	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	"K14780|0|hsa:57647|DHX37, DDX37; DEAH (Asp-Glu-Ala-His) box polypeptide 37 (EC:3.6.4.13); K14780 ATP-dependent RNA helicase DHX37/DHR1 [EC:3.6.4.13] (A)"	--	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; AAA domain;; Type II/IV secretion system protein	Probable ATP-dependent RNA helicase DHX37 GN=DHX37 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DHX37 [Ceratotherium simum simum]
ENSG00000150991(UBC)	--	370.1446445	14063	396.0489439	15852	336.7343641	13412	414.8764888	16295	366.6362117	14312	438.4527331	17269	0.994688647	0.181674246	normal	0.995003786	-0.168849176	normal	0.96180525	0.356333214	normal	0.619013198	0.122743665	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K08770|0|rno:50522|Ubc; ubiquitin C; K08770 ubiquitin C (A)	PPAR signaling pathway (ko03320)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin-like domain;; Telomere stability and silencing;; Ubiquitin-2 like Rad60 SUMO-like;; DUF2407 ubiquitin-like domain;; Protein of unknown function (DUF2870);; GLUT4 regulating protein TUG;; FlgD Ig-like domain;; Ubiquitin-specific protease C-terminal;; Plexin cytoplasmic RasGAP domain	Ubiquitin (Precursor) GN=UBB OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polyubiquitin-like [Monodelphis domestica]
ENSG00000150995(ITPR1)	--	3.758876985	807	2.504404116	515	2.938525116	631	1.90313352	407	1.851688286	396	2.10230841	404	1.96E-06	-1.015592952	down	0.744481018	-0.399157646	normal	0.04118351	-0.649613944	normal	0.015571799	-0.715473706	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: calcium channel activity (GO:0005262);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04958|0|mcf:101865389|uncharacterized LOC101865389; K04958 inositol 1,4,5-triphosphate receptor type 1 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Huntington's disease (ko05016);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	"RIH domain;; Inositol 1,4,5-trisphosphate/ryanodine receptor;; MIR domain;; RyR and IP3R Homology associated;; Ion transport protein"	"Inositol 1,4,5-trisphosphate receptor type 1 GN=ITPR1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: inositol 1,4,5-trisphosphate receptor type 1 isoform X2 [Tupaia chinensis]"
ENSG00000151005(TKTL2)	--	0	0	0	0	0	0	0.0225884	1	0.02209	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624);; "	K00615|0|hsa:84076|TKTL2; transketolase-like 2 (EC:2.2.1.1); K00615 transketolase [EC:2.2.1.1] (A)	Pentose phosphate pathway (ko00030);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	"Transketolase, thiamine diphosphate binding domain;; Transketolase, pyrimidine binding domain;; Transketolase, C-terminal domain;; Dehydrogenase E1 component;; 1-deoxy-D-xylulose-5-phosphate synthase;; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain"	Transketolase-like protein 2 GN=TKTL2 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: transketolase-like protein 2 isoform X1 [Pteropus alecto] 
ENSG00000151006(PRSS53)	--	129.0360316	1442	110.8450997	1298	119.2502174	1372	126.495496	1456	122.0505239	1369	118.3333109	1334	0.983594296	-0.016875179	normal	0.981370985	0.055342718	normal	0.982215013	-0.04875875	normal	0.989936683	-0.00504174	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986);; Trypsin-like peptidase domain	Serine protease 53 (Precursor) GN=PRSS53 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine protease 53 [Camelus bactrianus] 
ENSG00000151012(SLC7A11)	--	42.5924	5778	55.9248	7555	44.4077	5876	42.4013	5823	37.5485	5093	65.6056	8921	0.994128277	-0.019634648	normal	0.13111261	-0.590197705	normal	0.111943862	0.59395466	normal	0.975714352	0.026207196	normal	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13869|0|ptr:471310|SLC7A11; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; K13869 solute carrier family 7 (L-type amino acid transporter), member 11 (A)"	--	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease	Cystine/glutamate transporter GN=SLC7A11 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: cystine/glutamate transporter [Equus caballus] 
ENSG00000151014(NOCT)	--	3.661472	172	4.563252751	252	6.741995	270	4.7316336	254	5.045279	233	4.940822221	274	0.532823342	0.52768721	normal	0.958046487	-0.133685723	normal	0.967391185	0.012853578	normal	0.774759408	0.112332455	normal	[A]	RNA processing and modification	--	"K18764|0|hsa:25819|CCRN4L, CCR4L, Ccr4c, NOC; CCR4 carbon catabolite repression 4-like (S. cerevisiae) (EC:3.1.13.4); K18764 nocturnin [EC:3.1.13.4] (A)"	--	[K]	Transcription	Endonuclease/Exonuclease/phosphatase family	Nocturnin GN=CCRN4L OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: nocturnin isoform 1 [Odobenus rosmarus divergens]
ENSG00000151023(ENKUR)	--	0	0	0	0	0.042618039	1	0.082547161	4	0.0907958	4	0.10291734	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Calmodulin-binding	Enkurin GN=ENKUR OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: enkurin [Tupaia chinensis]
ENSG00000151025(GPR158)	--	0.0368436	5	0.0148246	2	0.00732599	0	0.00735476	1	0.049866	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08469|0|hsa:57512|GPR158; G protein-coupled receptor 158; K08469 G protein-coupled receptor 158 (A)	--	[S]	Function unknown	7 transmembrane sweet-taste receptor of 3 GCPR	Probable G-protein coupled receptor 158 (Precursor) GN=GPR158 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: probable G-protein coupled receptor 158 [Ceratotherium simum simum]
ENSG00000151062(CACNA2D4)	--	0	0	0	0	0	0	0	0	0	0	0.0386772	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04861|0|hsa:93589|CACNA2D4, RCD4; calcium channel, voltage-dependent, alpha 2/delta subunit 4; K04861 voltage-dependent calcium channel alpha-2/delta-4 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	VWA N-terminal;; Cache domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Voltage-dependent calcium channel subunit delta-4 (Precursor) GN=CACNA2D4 OS=Homo sapiens (Human) PE=1 SV=2	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-4 [Felis catus]
ENSG00000151065(DCP1B)	--	5.114943113	234	4.49502375	190	5.186813312	225	5.842253195	281	6.759745114	291	6.709232144	310	0.93689444	0.231838763	normal	0.301889004	0.58977369	normal	0.681855449	0.451456118	normal	0.106796228	0.421819595	normal	--	--	Biological Process: deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0000290);; Molecular Function: enzyme activator activity (GO:0008047);; Biological Process: positive regulation of catalytic activity (GO:0043085);; 	"K12611|0|hsa:196513|DCP1B, DCP1, hDcp1b; decapping mRNA 1B; K12611 mRNA-decapping enzyme 1B [EC:3.-.-.-] (A)"	RNA degradation (ko03018)	[KA]	Transcription;; RNA processing and modification	Dcp1-like decapping family	mRNA-decapping enzyme 1B GN=DCP1B OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: mRNA-decapping enzyme 1B isoform 1 [Ceratotherium simum simum]
ENSG00000151067(CACNA1C)	--	0	0	0.170297	1	0	0	0.006652491	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04850|0|mcf:101865175|uncharacterized LOC101865175; K04850 voltage-dependent calcium channel L type alpha-1C (A)	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Alzheimer's disease (ko05010);; Amphetamine addiction (ko05031);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Voltage gated calcium channel IQ domain;; Polycystin cation channel	Voltage-dependent L-type calcium channel subunit alpha-1C GN=CACNA1C OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent L-type calcium channel subunit alpha-1C isoform X6 [Pteropus alecto]
ENSG00000151090(THRB)	--	5.286222862	353	4.608505831	268	4.647149949	306	2.733639535	251	1.760699439	158	3.404322286	240	0.437648973	-0.520113941	normal	0.028856399	-0.777948357	normal	0.849624281	-0.356792561	normal	0.051054464	-0.535860469	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08362|0|cjc:100394325|THRB; thyroid hormone receptor, beta; K08362 thyroid hormone receptor beta (A)"	Neuroactive ligand-receptor interaction (ko04080);; Thyroid hormone signaling pathway (ko04919)	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Thyroid hormone receptor beta GN=THRB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	hypothetical protein PANDA_017978 [Ailuropoda melanoleuca]
ENSG00000151092(NGLY1)	--	15.15899227	618	13.09812664	547	14.06830951	571	11.79023882	478	11.57365061	462	11.90877519	486	0.724059874	-0.400293304	normal	0.918914916	-0.264278422	normal	0.932796599	-0.240135706	normal	0.146033814	-0.304956864	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: glycoprotein catabolic process (GO:0006516);; 	K01456|0|ptr:460233|NGLY1; N-glycanase 1; K01456 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase [EC:3.5.1.52] (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	PUB domain;; Transglutaminase-like superfamily;; Rad4 transglutaminase-like domain;; Domain of unknown function (DUF750)	Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase GN=NGLY1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase isoform 1 [Odobenus rosmarus divergens]
ENSG00000151093(OXSM)	--	11.681747	269	13.286625	247	15.744692	237	11.850434	263	10.40073307	235	12.059054	267	0.965652632	-0.063011635	normal	0.962379825	-0.092694912	normal	0.954739308	0.16268271	normal	1	0.001483365	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	--	"K09458|0|ptr:460234|OXSM; 3-oxoacyl-ACP synthase, mitochondrial; K09458 3-oxoacyl-[acyl-carrier-protein] synthase II [EC:2.3.1.179] (A)"	Fatty acid biosynthesis (ko00061);; Biotin metabolism (ko00780);; Fatty acid metabolism (ko01212)	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	"Beta-ketoacyl synthase, N-terminal domain;; Beta-ketoacyl synthase, C-terminal domain;; Thiolase, N-terminal domain"	"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (Precursor) GN=OXSM OS=Homo sapiens (Human) PE=1 SV=1"	IQ	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial [Galeopterus variegatus]"
ENSG00000151116(UEVLD)	--	14.92568055	802	12.94376432	713	14.82674456	835	16.61592038	909	14.53956635	805	14.4583026	818	0.967092085	0.149576522	normal	0.964262326	0.153353896	normal	0.976838848	-0.037897448	normal	0.73761384	0.086269008	normal	[C]	Energy production and conversion	"Biological Process: cellular protein modification process (GO:0006464);; Biological Process: protein transport (GO:0015031);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	[C]	Energy production and conversion	"UEV domain;; lactate/malate dehydrogenase, NAD binding domain;; lactate/malate dehydrogenase, alpha/beta C-terminal domain"	Ubiquitin-conjugating enzyme E2 variant 3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 variant 3 isoform 1 [Dasypus novemcinctus]
ENSG00000151117(TMEM86A)	--	0.20897	14	0.0872423	6	0.0872567	5	0.432955	29	0.409478	27	0.40151	27	0.911096512	0.946342602	normal	0.190128747	1.905559034	normal	0.084483317	2.123238775	normal	0.007042687	1.70888777	up	[S]	Function unknown	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	YhhN-like protein	Lysoplasmalogenase-like protein TMEM86A GN=TMEM86A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: lysoplasmalogenase-like protein TMEM86A [Felis catus]
ENSG00000151131(C12orf45)	--	8.426034085	374	8.121257421	399	7.879599345	318	7.666612204	427	7.425002757	427	6.6624537	366	0.95620558	0.159751042	normal	0.966519424	0.076141771	normal	0.94769841	0.193666311	normal	0.638872502	0.139272939	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4598)	Uncharacterized protein C12orf45 GN=C12orf45 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C12orf45 homolog [Oryctolagus cuniculus]
ENSG00000151135(TMEM263)	--	25.42289336	1135	26.87614115	1257	24.92787149	1125	33.84609896	1582	34.5659924	1565	32.08227525	1460	0.559708489	0.447709646	normal	0.919967164	0.294433441	normal	0.813104169	0.367317321	normal	0.019902892	0.367938972	normal	--	--	--	--	--	--	--	"Transmembrane protein C12orf23, UPF0444"	Transmembrane protein 263 GN=TMEM263 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	transmembrane protein 263 [Bos taurus] 
ENSG00000151136(BTBD11)	--	24.92740913	2096	18.65103707	1654	25.75183355	1906	23.41125256	2106	24.434253	2080	17.02456459	1564	0.987182571	-0.023948031	normal	0.918216803	0.308945368	normal	0.92664733	-0.293341669	normal	0.998579403	0.001873248	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10483|0|ggo:101148139|BTBD11; ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform 1; K10483 BTB/POZ domain-containing protein 11 (A)	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; BTB/POZ domain;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies)	Ankyrin repeat and BTB/POZ domain-containing protein BTBD11 GN=BTBD11 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat and BTB/POZ domain-containing protein BTBD11 isoform 1 [Odobenus rosmarus divergens]
ENSG00000151148(UBE3B)	--	11.73347833	1091	9.120921621	998	10.90337419	1186	11.55412256	1177	10.64704867	1144	11.80688496	1215	0.978706844	0.078524477	normal	0.965498523	0.17530052	normal	0.981444841	0.026527442	normal	0.70953558	0.089765218	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	K10588|0|ggo:101133121|UBE3B; ubiquitin-protein ligase E3B isoform 1; K10588 ubiquitin-protein ligase E3 B [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; IQ calmodulin-binding motif	Ubiquitin-protein ligase E3B GN=UBE3B OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-protein ligase E3B isoform 1 [Odobenus rosmarus divergens] 
ENSG00000151150(ANK3)	--	2.046412964	70	1.621521572	118	1.38939846	67	2.439102054	126	3.382855627	204	3.140807858	211	0.211120004	0.803843512	normal	0.086211521	0.760853528	normal	6.29E-09	1.624941157	up	0.018558887	1.06479733	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K10380|0|pps:100978708|ANK3; ankyrin 3, node of Ranvier (ankyrin G); K10380 ankyrin (A)"	Proteoglycans in cancer (ko05205)	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; ZU5 domain;; Death domain	Ankyrin-3 GN=ANK3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ankyrin-3 isoform X3 [Equus przewalskii]
ENSG00000151151(IPMK)	--	4.4197359	345	4.290100975	333	4.696897468	354	6.273405321	496	5.618426001	439	6.482308081	504	0.461648405	0.49107877	normal	0.801345367	0.375781707	normal	0.427321984	0.49958533	normal	0.027355738	0.458512079	normal	--	--	"Molecular Function: inositol-1,4,5-trisphosphate 3-kinase activity (GO:0008440);; "	K00328|0|hsa:253430|IPMK; inositol polyphosphate multikinase (EC:2.7.1.151); K00328 inositol-polyphosphate multikinase [EC:2.7.1.151] (A)	Inositol phosphate metabolism (ko00562)	[KIT]	Transcription;; Lipid transport and metabolism;; Signal transduction mechanisms	Inositol polyphosphate kinase	Inositol polyphosphate multikinase GN=IPMK OS=Homo sapiens (Human) PE=1 SV=1	IKT	Lipid transport and metabolism;; Transcription;; Signal transduction mechanisms	PREDICTED: inositol polyphosphate multikinase isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000151164(RAD9B)	--	0.164197081	7	0	0	0.276584828	10	0.212713092	9	0.138326877	5	0.1933597	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: DNA damage checkpoint (GO:0000077);; Cellular Component: checkpoint clamp complex (GO:0030896);; 	K10995|0|ptr:452238|RAD9B; RAD9 homolog B (S. pombe); K10995 cell cycle checkpoint control protein RAD9B (A)	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Rad9	Cell cycle checkpoint control protein RAD9B GN=RAD9B OS=Homo sapiens (Human) PE=1 SV=2	DL	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	PREDICTED: cell cycle checkpoint control protein RAD9B [Odobenus rosmarus divergens]
ENSG00000151176(PLBD2)	--	33.76854	2806	37.68229	3077	31.94325	2626	34.93538	2852	38.8693	3201	40.29902	3362	0.989786661	-0.007369288	normal	0.990032174	0.035554543	normal	0.895561928	0.347983826	normal	0.553119185	0.125079189	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Phospholipase B	Putative phospholipase B-like 2 45 kDa form (Precursor) GN=PLBD2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: putative phospholipase B-like 2 [Pteropus alecto]
ENSG00000151208(DLG5)	--	16.1668655	2662	17.748316	2898	16.9035665	2774	18.29026116	2848	18.621483	3023	17.5878	2823	0.988618429	0.066569163	normal	0.989528172	0.039476656	normal	0.989646647	0.016960733	normal	0.884468846	0.039810573	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[F]	Nucleotide transport and metabolism	PDZ domain (Also known as DHR or GLGF);; Takusan;; PDZ domain;; Guanylate kinase	Disks large homolog 5 GN=DLG5 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: disks large homolog 5 [Ceratotherium simum simum]
ENSG00000151224(MAT1A)	--	0.043926274	3	0.071958162	5	0.085280677	5	0.04593648	3	0.085827849	5	0.261433563	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: methionine adenosyltransferase activity (GO:0004478);; Biological Process: S-adenosylmethionine biosynthetic process (GO:0006556);; 	"K00789|0|ptr:450555|MAT1A; methionine adenosyltransferase I, alpha; K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] (A)"	Cysteine and methionine metabolism (ko00270);; Biosynthesis of amino acids (ko01230)	[H]	Coenzyme transport and metabolism	"S-adenosylmethionine synthetase, C-terminal domain;; S-adenosylmethionine synthetase, central domain;; S-adenosylmethionine synthetase, N-terminal domain"	S-adenosylmethionine synthase isoform type-1 GN=MAT1A OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	S-adenosylmethionine synthase isoform type-1 [Sus scrofa] 
ENSG00000151229(SLC2A13)	--	9.981775906	450	9.474544415	489	7.203854093	393	8.983088518	476	9.1512989	473	10.28478	499	0.969856687	0.050038191	normal	0.968474888	-0.069203216	normal	0.854757691	0.335072227	normal	0.741325488	0.099086851	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08150|0|hsa:114134|SLC2A13, HMIT; solute carrier family 2 (facilitated glucose transporter), member 13; K08150 MFS transporter, SP family, solute carrier family 2 (myo-inositol transporter), member 13 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Proton myo-inositol cotransporter GN=SLC2A13 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	proton myo-inositol cotransporter [Bos taurus] 
ENSG00000151233(GXYLT1)	--	7.869688653	498	7.945766503	572	7.889156	533	9.749739	719	7.623699262	588	8.913860438	688	0.378104322	0.49772946	normal	0.972516254	0.018326662	normal	0.813099851	0.359082528	normal	0.146118406	0.294165088	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K13676|0|ptr:466957|GXYLT1, GLT8D3; glucoside xylosyltransferase 1; K13676 UDP-xylose:glucoside alpha-1,3-xylosyltransferase [EC:2.4.2.-] (A)"	Other types of O-glycan biosynthesis (ko00514)	[G]	Carbohydrate transport and metabolism	Glycosyl transferase family 8	Glucoside xylosyltransferase 1 GN=GXYLT1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: glucoside xylosyltransferase 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000151239(TWF1)	--	55.1436291	2572	61.14964345	2743	60.36224196	2746	78.8175325	3636	68.9474965	3211	66.86242	3072	0.543206829	0.468392935	normal	0.976914347	0.205736562	normal	0.983927727	0.153475199	normal	0.096018881	0.277554031	normal	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	"K08870|0|hsa:5756|TWF1, A6, PTK9; twinfilin actin-binding protein 1; K08870 twinfilin (A)"	--	[W]	Extracellular structures	Cofilin/tropomyosin-type actin-binding protein	Twinfilin-1 GN=TWF1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: twinfilin-1 [Galeopterus variegatus]
ENSG00000151240(DIP2C)	--	5.09387001	783	4.624996533	655	4.192116127	663	4.4405705	697	4.896814294	751	4.005681141	608	0.953543491	-0.198273238	normal	0.95854182	0.175512775	normal	0.96579884	-0.132912292	normal	0.863928711	-0.052850509	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	AMP-binding enzyme;; DMAP1-binding Domain	Disco-interacting protein 2 homolog C GN=DIP2C OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: disco-interacting protein 2 homolog C isoform X1 [Oryctolagus cuniculus]
ENSG00000151247(EIF4E)	--	56.35695013	1336	57.83031315	1404	55.68968103	1292	57.7011364	1481	52.01893413	1367	46.06456697	1137	0.97840732	0.117690786	normal	0.981641269	-0.05989087	normal	0.964104075	-0.192424985	normal	0.892283724	-0.038984727	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation initiation factor activity (GO:0003743);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: translational initiation (GO:0006413);; 	K03259|3.2739e-137|phd:102327611|EIF4E; eukaryotic translation initiation factor 4E; K03259 translation initiation factor 4E (A)	RNA transport (ko03013);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Insulin signaling pathway (ko04910)	[J]	"Translation, ribosomal structure and biogenesis"	Eukaryotic initiation factor 4E	Eukaryotic translation initiation factor 4E GN=EIF4E OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	"Eukaryotic translation initiation factor 4E, partial [Bos mutus]"
ENSG00000151276(MAGI1)	--	2.504656261	353	2.280573081	349	2.822957176	352	2.383662663	344	3.32736086	459	2.80054745	416	0.96660814	-0.067792959	normal	0.804646087	0.372429474	normal	0.934929187	0.231799604	normal	0.49764287	0.189284218	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05631|0|hsa:9223|MAGI1, AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, Magi1d, TNRC19, WWP3; membrane associated guanylate kinase, WW and PDZ domain containing 1; K05631 atrophin-1 interacting protein 3 (BAI1-associated protein 1) (A)"	Rap1 signaling pathway (ko04015);; Tight junction (ko04530)	[R]	General function prediction only	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; WW domain;; Guanylate kinase;; Tricorn protease PDZ domain	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 GN=MAGI1 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1-like isoform X11 [Bubalus bubalis]"
ENSG00000151287(TEX30)	--	9.530562127	162	10.19240171	167	11.40173439	194	8.74184302	149	6.97972199	118	6.73378627	116	0.959799697	-0.150029439	normal	0.701561049	-0.516889685	normal	0.114802411	-0.742653681	normal	0.158649208	-0.471200867	normal	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; Dienelactone hydrolase family	Testis-expressed sequence 30 protein GN=TEX30 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 30 protein isoform X1 [Equus caballus] 
ENSG00000151292(CSNK1G3)	--	17.41900586	1006	18.91829932	1000	15.58773764	1023	14.87013264	960	14.89786608	961	14.59299907	979	0.97546178	-0.098202699	normal	0.976448374	-0.078696807	normal	0.97766315	-0.071608601	normal	0.734790479	-0.08388087	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08958|0|ptr:462027|CSNK1G3; casein kinase 1, gamma 3; K08958 casein kinase 1, gamma [EC:2.7.11.1] (A)"	Hedgehog signaling pathway (ko04340)	[T]	Signal transduction mechanisms	Protein kinase domain;; Casein kinase 1 gamma C terminal;; Protein tyrosine kinase	Casein kinase I isoform gamma-3 GN=CSNK1G3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: casein kinase I isoform gamma-3 isoform X2 [Ailuropoda melanoleuca] 
ENSG00000151304(SRFBP1)	--	6.679578972	510	8.879710899	654	7.659394025	570	7.28844	563	8.07254	545	7.658069	543	0.966484512	0.111485677	normal	0.907106704	-0.283741087	normal	0.970189559	-0.078088869	normal	0.747209522	-0.092156071	normal	--	--	--	--	--	--	--	BUD22	Serum response factor-binding protein 1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: serum response factor-binding protein 1 [Galeopterus variegatus]
ENSG00000151320(AKAP6)	--	0.507712417	79	0.38656956	63	0.573258254	67	1.012896028	152	1.315531389	204	1.120993109	176	0.039225476	0.900483281	normal	7.87E-09	1.650482166	up	8.99E-06	1.365319606	up	9.36E-06	1.327209883	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16523|0|hsa:9472|AKAP6, ADAP100, ADAP6, AKAP100, PRKA6, mAKAP; A kinase (PRKA) anchor protein 6; K16523 A-kinase anchor protein 6 (A)"	--	--	--	Spectrin repeat	A-kinase anchor protein 6 GN=AKAP6 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 6 [Tupaia chinensis]
ENSG00000151322(NPAS3)	--	0.270246463	2	0	0	0.01029831	0	0	0	0	0	0.010333087	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09098|0|mcf:102126572|NPAS3; neuronal PAS domain protein 3; K09098 neuronal PAS domain-containing protein 1/3 (A)	--	[TK]	Signal transduction mechanisms;; Transcription	PAS fold;; PAS domain;; PAS fold;; PAS domain	Neuronal PAS domain-containing protein 3 GN=NPAS3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: neuronal PAS domain-containing protein 3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000151327(FAM177A1)	--	27.34859581	698	24.502536	738	26.66057696	720	30.50712086	840	26.85796986	724	30.29964305	698	0.93986762	0.23585626	normal	0.974356048	-0.048956389	normal	0.974458014	-0.052948355	normal	0.875136822	0.047445206	normal	--	--	--	--	--	--	--	FAM177 family	Protein FAM177A1 GN=FAM177A1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM177A1 [Orcinus orca]
ENSG00000151332(MBIP)	--	8.909389001	257	8.652129858	247	8.816380831	247	8.62821413	246	8.1859553	238	8.849051833	257	0.96346481	-0.093371672	normal	0.963712734	-0.074511237	normal	0.966253662	0.048673707	normal	0.932957405	-0.040442424	normal	--	--	--	--	--	--	--	--	MAP3K12-binding inhibitory protein 1 GN=MBIP OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: MAP3K12-binding inhibitory protein 1 [Orcinus orca]
ENSG00000151338(MIPOL1)-2	--	2.138116268	150	3.095974167	181	2.710788255	174	2.487365306	163	2.22649689	179	2.843142838	137	0.965145539	0.088210339	normal	0.965466738	-0.037144588	normal	0.897174486	-0.349768528	normal	0.843370735	-0.097797806	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000151338(MIPOL1)-3	--	0	0	0	0	0	0	0.0280264	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000151348(EXT2)	--	43.198676	2656	37.932642	2344	41.524536	2552	49.345968	3033	51.548236	3153	48.932853	2993	0.982921018	0.160571123	normal	0.78311492	0.406099397	normal	0.972380329	0.221551158	normal	0.12518289	0.260339465	normal	--	--	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K02367|0|hsa:2132|EXT2, SOTV; exostosin glycosyltransferase 2 (EC:2.4.1.225 2.4.1.224); K02367 glucuronyl/N-acetylglucosaminyl transferase EXT2 [EC:2.4.1.224 2.4.1.225] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[GMW]	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Extracellular structures	Glycosyl transferase family 64 domain;; Exostosin family	Exostosin-2 GN=EXT2 OS=Homo sapiens (Human) PE=1 SV=1	GMW	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: exostosin-2 isoform X3 [Canis lupus familiaris]
ENSG00000151353(TMEM18)	--	15.84222295	447	15.27232108	428	15.05742596	392	14.46863602	344	12.47937034	319	12.38126955	289	0.73093252	-0.407098205	normal	0.649200027	-0.443658025	normal	0.650440357	-0.446063427	normal	0.048245856	-0.434276721	normal	--	--	--	--	--	--	--	Transmembrane protein 18	Transmembrane protein 18 GN=TMEM18 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 18-like [Chrysochloris asiatica]
ENSG00000151364(KCTD14)	--	151.33689	1230	155.2308198	1374	164.335716	1307	212.4475006	1705	190.228582	1609	178.548878	1484	0.596417979	0.43981274	normal	0.9642858	0.20614592	normal	0.970427	0.174750636	normal	0.107111089	0.273276964	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD14 GN=KCTD14 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD14 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000151365(THRSP)	--	0	0	0	0	0	0	0	0	0.0986377	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Thyroid hormone-inducible hepatic protein Spot 14	Thyroid hormone-inducible hepatic protein GN=THRSP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: thyroid hormone-inducible hepatic protein [Ochotona princeps]
ENSG00000151376(ME3)	--	29.937642	462	17.93306671	429	29.36685636	510	26.80146162	562	34.02667782	596	32.37211146	584	0.926570872	0.251086988	normal	0.586297869	0.451552154	normal	0.952904768	0.186662073	normal	0.16787614	0.293500601	normal	[C]	Energy production and conversion	Molecular Function: malate dehydrogenase (decarboxylating) (NAD+) activity (GO:0004471);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00029|0|hsa:10873|ME3, NADP-ME; malic enzyme 3, NADP(+)-dependent, mitochondrial (EC:1.1.1.40); K00029 malate dehydrogenase (oxaloacetate-decarboxylating)(NADP+) [EC:1.1.1.40] (A)"	Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	"Malic enzyme, NAD binding domain;; Malic enzyme, N-terminal domain"	"NADP-dependent malic enzyme, mitochondrial (Precursor) GN=ME3 OS=Homo sapiens (Human) PE=2 SV=2"	C	Energy production and conversion	"PREDICTED: NADP-dependent malic enzyme, mitochondrial isoform 1 [Ceratotherium simum simum] "
ENSG00000151388(ADAMTS12)	--	2.51916948	205	3.347638117	265	6.603107842	266	1.416095691	47	0.698296953	38	0.707681599	37	9.60E-14	-2.119484901	down	0	-2.774784484	down	0	-2.804319625	down	9.01E-21	-2.61463491	down	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08626|0|hsa:81792|ADAMTS12, PRO4389; ADAM metallopeptidase with thrombospondin type 1 motif, 12; K08626 a disintegrin and metalloproteinase with thrombospondin motifs 12 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Thrombospondin type 1 domain;; Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 12 (Precursor) GN=ADAMTS12 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 12 [Lipotes vexillifer]
ENSG00000151413(NUBPL)	--	7.575596584	372	5.650265078	279	8.429769903	357	8.48026571	421	7.3635759	358	6.878699491	337	0.958502455	0.14711396	normal	0.864113078	0.336653373	normal	0.964934601	-0.091069797	normal	0.693558522	0.125164474	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	K03593|0|nle:100590062|NUBPL; nucleotide binding protein-like; K03593 ATP-binding protein involved in chromosome partitioning (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"ParA/MinD ATPase like;; CobQ/CobB/MinD/ParA nucleotide binding domain;; AAA domain;; ATPase MipZ;; 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family"	Iron-sulfur protein NUBPL (Precursor) GN=NUBPL OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	iron-sulfur protein NUBPL [Bos taurus] 
ENSG00000151414(NEK7)	--	13.81507397	705	14.36300038	735	11.95253746	642	21.52348316	1181	18.83552197	971	18.74585395	986	0.005170388	0.712270023	normal	0.778464287	0.379618981	normal	0.059344951	0.609555652	normal	0.00024484	0.569857231	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08857|0|ptr:736415|NEK7; NIMA-related kinase 7; K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase Nek7 GN=NEK7 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase Nek7 isoform X1 [Mustela putorius furo] 
ENSG00000151422(FER)	--	4.477795774	705	4.438783379	716	7.273875357	608	4.020039218	586	3.7140359	550	3.714871989	504	0.895660106	-0.296844047	normal	0.725900879	-0.40098511	normal	0.910263442	-0.278177898	normal	0.092143744	-0.328986075	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08889|0|hsa:2241|FER, FerT, PPP1R74, Pe1Fe10, Pe1Fe13, Pe1Fe3, Pe1Fe6, TYK3; fer (fps/fes related) tyrosine kinase (EC:2.7.10.2); K08889 tyrosine-protein kinase Fer [EC:2.7.10.2] (A)"	Adherens junction (ko04520)	[T]	Signal transduction mechanisms	"Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; Fes/CIP4, and EFC/F-BAR homology domain"	Tyrosine-protein kinase Fer GN=FER OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase Fer [Ursus maritimus]
ENSG00000151445(VIPAS39)	--	9.118209271	484	9.470442294	475	9.219745909	489	9.134599981	484	7.787359932	406	10.08951936	523	0.970994776	-0.030734699	normal	0.927667403	-0.247022656	normal	0.9683406	0.088420586	normal	0.868369867	-0.056295597	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: intracellular protein transport (GO:0006886);; 	--	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	"Golgin subfamily A member 5;; Vps16, C-terminal region"	Spermatogenesis-defective protein 39 homolog GN=VIPAS39 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: spermatogenesis-defective protein 39 homolog [Felis catus] 
ENSG00000151458(ANKRD50)	--	6.06364431	830	7.358398726	871	5.134914	744	9.704606971	1427	13.66608232	1792	9.711586606	1424	0.001655166	0.749899218	normal	4.27E-07	1.018141317	up	8.58E-06	0.926897803	normal	3.48E-07	0.903905784	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 50 GN=ANKRD50 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 50 isoform 1 [Ceratotherium simum simum]
ENSG00000151461(UPF2)	--	11.91207428	1506	12.51689116	1578	13.49420632	1680	10.52749501	1333	8.824911	1108	9.119701	1150	0.963198521	-0.206652975	normal	0.235847473	-0.530955213	normal	0.144262745	-0.554511784	normal	0.004818035	-0.429349056	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	"K14327|0|hsa:26019|UPF2, HUPF2, RENT2, smg-3; UPF2 regulator of nonsense transcripts homolog (yeast); K14327 regulator of nonsense transcripts 2 (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	MIF4G domain;; Up-frameshift suppressor 2	Regulator of nonsense transcripts 2 GN=UPF2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: regulator of nonsense transcripts 2 [Bos mutus]
ENSG00000151465(CDC123)	--	71.032807	1801	66.42787739	1694	71.65392507	1786	77.822967	1975	78.542678	1952	72.42896082	1833	0.983248019	0.102138985	normal	0.97310211	0.182940381	normal	0.985716211	0.029158891	normal	0.636377246	0.103911445	normal	--	--	Biological Process: cell cycle (GO:0007049);; 	--	--	[S]	Function unknown	D123	Cell division cycle protein 123 homolog GN=CDC123 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cell division cycle protein 123 homolog [Mustela putorius furo] 
ENSG00000151466(SCLT1)	--	3.202211934	137	6.319942748	228	3.853389215	173	6.039089514	247	4.814839	201	5.373703962	201	0.021359846	0.812625718	normal	0.94624665	-0.201837912	normal	0.948238626	0.206456267	normal	0.505322065	0.248523648	normal	--	--	--	--	--	--	--	--	Sodium channel and clathrin linker 1 GN=SCLT1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: sodium channel and clathrin linker 1 [Ceratotherium simum simum]
ENSG00000151468(CCDC3)	--	1.2296141	57	0.927221	43	0.849044	39	0.130765	6	0.253897	11	0.194098	9	1.07E-07	-2.984661447	down	0.011400246	-1.850626145	normal	0.013767421	-1.953823202	normal	6.76E-06	-2.438789203	down	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 3 (Precursor) GN=CCDC3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 3 [Oryctolagus cuniculus]
ENSG00000151470(C4orf33)	--	6.060584	154	6.655375573	166	4.7787803	118	5.455704921	141	6.913489684	175	6.452602977	171	0.959629076	-0.156435601	normal	0.965068956	0.054263636	normal	0.689625825	0.521337525	normal	0.782066727	0.131897155	normal	--	--	--	--	--	--	--	--	UPF0462 protein C4orf33 GN=C4orf33 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0462 protein C4orf33 homolog [Felis catus] 
ENSG00000151474(FRMD4A)	--	1.682517013	171	2.343712001	167	2.269943412	228	2.7246589	218	2.307905246	201	2.123147839	197	0.90438452	0.316972169	normal	0.937089036	0.243905238	normal	0.943741266	-0.217575626	normal	0.821676026	0.101179648	normal	--	--	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF3338);; FERM central domain;; FERM C-terminal PH-like domain;; FERM N-terminal domain	FERM domain-containing protein 4A GN=FRMD4A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: FERM domain-containing protein 4A-like isoform X1 [Elephantulus edwardii]
ENSG00000151490(PTPRO)	--	0.185916405	18	0.636604003	27	0.564539213	30	0.403603918	23	0.261009642	19	0.6254808	41	0.986318856	0.300103375	normal	0.975166622	-0.495163956	normal	0.967271012	0.424020386	normal	0.911866656	0.127250579	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18035|0|pps:100980526|PTPRO; protein tyrosine phosphatase, receptor type, O; K18035 receptor-type tyrosine-protein phosphatase O [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase;; Fibronectin type III domain	Receptor-type tyrosine-protein phosphatase O (Precursor) GN=PTPRO OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase O isoform X2 [Canis lupus familiaris] 
ENSG00000151491(EPS8)	--	15.62048951	1224	20.89942249	1440	15.32937169	1204	25.36384482	1991	24.0164571	1845	31.77199318	2486	0.011131671	0.670391659	normal	0.883402715	0.335813183	normal	7.64E-08	1.036773574	up	0.001559909	0.688020515	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17277|0|hsa:2059|EPS8, DFNB102; epidermal growth factor receptor pathway substrate 8; K17277 epidermal growth factor receptor kinase substrate 8 (A)"	--	[T]	Signal transduction mechanisms	Phosphotyrosine-binding domain;; SH3 domain;; Variant SH3 domain;; Phosphotyrosine interaction domain (PTB/PID);; Variant SH3 domain;; Bacterial SH3 domain	Epidermal growth factor receptor kinase substrate 8 GN=EPS8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor receptor kinase substrate 8 isoform 3 [Dasypus novemcinctus]
ENSG00000151498(ACAD8)	--	7.460054222	302	4.848306656	206	7.516825904	315	7.849673626	326	7.915979	313	7.633431894	315	0.965246012	0.079103768	normal	0.309081317	0.57862264	normal	0.968109474	-0.008251826	normal	0.53086332	0.192266287	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K11538|0|hsa:27034|ACAD8, ACAD-8, ARC42; acyl-CoA dehydrogenase family, member 8; K11538 isobutyryl-CoA dehydrogenase [EC:1.3.99.-] (A)"	"Valine, leucine and isoleucine degradation (ko00280)"	[I]	Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, middle domain"	"Isobutyryl-CoA dehydrogenase, mitochondrial (Precursor) GN=ACAD8 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: isobutyryl-CoA dehydrogenase, mitochondrial [Ceratotherium simum simum]"
ENSG00000151500(THYN1)	--	10.93570255	182	10.929743	188	11.375123	195	12.974736	214	14.51679681	243	12.94152	223	0.948660275	0.201271907	normal	0.875553436	0.346340762	normal	0.951746836	0.183943267	normal	0.474015043	0.246362757	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	EVE domain	Thymocyte nuclear protein 1 GN=THYN1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: thymocyte nuclear protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000151502(VPS26B)	--	10.99666155	713	10.24563467	671	10.14853685	701	9.566891411	655	11.83973456	772	10.27507461	663	0.963304015	-0.152895532	normal	0.957745327	0.180482059	normal	0.971727939	-0.088500666	normal	0.96328771	-0.017577341	normal	--	--	--	K18466|0|ptr:451681|VPS26B; vacuolar protein sorting 26 homolog B (S. pombe); K18466 vacuolar protein sorting-associated protein 26 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar protein sorting-associated protein 26	Vacuolar protein sorting-associated protein 26B GN=VPS26B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 26B [Myotis lucifugus] 
ENSG00000151503(NCAPD3)	--	14.64738851	1472	13.76618098	1404	16.066304	1645	14.91443469	1521	12.76234242	1272	13.060536	1252	0.983937045	0.016393385	normal	0.971436346	-0.163685496	normal	0.731613138	-0.401719773	normal	0.342357377	-0.182083478	normal	--	--	--	"K11491|0|hsa:23310|NCAPD3, CAP-D3, CAPD3, hCAP-D3, hHCP-6, hcp-6; non-SMC condensin II complex, subunit D3; K11491 condensin-2 complex subunit D3 (A)"	--	[S]	Function unknown	non-SMC mitotic condensation complex subunit 1;; HEAT repeats;; HEAT repeat;; HEAT repeat associated with sister chromatid cohesion	Condensin-2 complex subunit D3 GN=NCAPD3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: condensin-2 complex subunit D3 [Galeopterus variegatus]
ENSG00000151532(VTI1A)	--	7.918395	886	7.093381912	809	8.054209	880	7.308856	841	9.423825616	1035	8.097208	903	0.97304203	-0.10584473	normal	0.863389931	0.333440317	normal	0.977966877	0.028882023	normal	0.724007262	0.089187482	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Cellular Component: membrane (GO:0016020);; 	K08493|6.24797e-121|nle:100588779|VTI1A; vesicle transport through interaction with t-SNAREs 1A; K08493 vesicle transport through interaction with t-SNAREs 1 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vesicle transport v-SNARE protein N-terminus;; Snare region anchored in the vesicle membrane C-terminus	Vesicle transport through interaction with t-SNAREs homolog 1A GN=VTI1A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle transport through interaction with t-SNAREs homolog 1A [Odobenus rosmarus divergens]
ENSG00000151552(QDPR)	--	23.41777958	554	22.10281985	556	22.189998	533	32.66525447	808	30.88380728	754	28.2076429	688	0.309936663	0.512454074	normal	0.680698904	0.417075562	normal	0.813099851	0.359082528	normal	0.015507901	0.431850314	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00357|4.11935e-161|hsa:5860|QDPR, DHPR, PKU2, SDR33C1; quinoid dihydropteridine reductase (EC:1.5.1.34); K00357 dihydropteridine reductase [EC:1.5.1.34] (A)"	Folate biosynthesis (ko00790)	[E]	Amino acid transport and metabolism	short chain dehydrogenase	Dihydropteridine reductase GN=QDPR OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: dihydropteridine reductase [Mustela putorius furo]
ENSG00000151553(FAM160B1)	--	6.937366476	595	7.781617625	662	7.310667686	613	8.11453086	701	9.55945036	784	9.745850894	817	0.949261659	0.205203932	normal	0.944732453	0.222129144	normal	0.703275063	0.405288636	normal	0.15478197	0.279075984	normal	--	--	--	--	--	[S]	Function unknown	Retinoic acid induced 16-like protein	Protein FAM160B1 GN=FAM160B1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM160B1 [Dasypus novemcinctus]
ENSG00000151572(ANO4)	--	0.051392026	2	0.029397592	2	0.051267511	1	0.051405372	2	0.09985261	3	0.02703413	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[S]	Function unknown	Calcium-activated chloride channel	Anoctamin-4 GN=ANO4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: anoctamin-4 [Tupaia chinensis]
ENSG00000151575(TEX9)	--	5.931056	173	6.208424	186	5.407347	153	5.36701	167	5.043552	156	6.19231508	176	0.965098963	-0.081023728	normal	0.92906572	-0.272758056	normal	0.952937911	0.191981772	normal	0.911866656	-0.058463455	normal	--	--	--	--	--	--	--	--	Testis-expressed sequence 9 protein GN=TEX9 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 9 protein isoform X1 [Equus przewalskii]
ENSG00000151576(QTRT2)	--	9.963735	668	11.12407718	737	11.780768	784	11.2056577	709	11.3693922	747	11.2264566	728	0.973909101	0.054982506	normal	0.9755254	-0.001978901	normal	0.970407099	-0.114976431	normal	0.945323837	-0.024204387	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Biological Process: tRNA modification (GO:0006400);; Molecular Function: transferase activity, transferring pentosyl groups (GO:0016763);; "	K15407|0|hsa:79691|QTRTD1; queuine tRNA-ribosyltransferase domain containing 1 (EC:2.4.2.29); K15407 queuine tRNA-ribosyltransferase subunit QTRTD1 [EC:2.4.2.29] (A)	--	[A]	RNA processing and modification	Queuine tRNA-ribosyltransferase	Queuine tRNA-ribosyltransferase subunit QTRTD1 {ECO:0000255|HAMAP-Rule:MF_03043} OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: queuine tRNA-ribosyltransferase subunit QTRTD1-like isoform X2 [Sus scrofa] 
ENSG00000151611(MMAA)	--	0.426165593	45	0.331431792	35	1.364998	66	0.927357	75	1.186423	70	0.68732	43	0.765923662	0.687771695	normal	0.368986041	0.949052811	normal	0.869160457	-0.609004179	normal	0.575552504	0.343105632	normal	[E]	Amino acid transport and metabolism	--	"K07588|0|hsa:166785|MMAA, cblA; methylmalonic aciduria (cobalamin deficiency) cblA type; K07588 LAO/AO transport system kinase [EC:2.7.-.-] (A)"	--	--	--	"ArgK protein;; CobW/HypB/UreG, nucleotide-binding domain"	"Methylmalonic aciduria type A protein, mitochondrial (Precursor) GN=MMAA OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: methylmalonic aciduria type A protein, mitochondrial [Equus caballus]"
ENSG00000151612(ZNF827)	--	3.784994739	403	2.881867366	468	2.46027682	385	3.989318975	486	3.677994638	548	3.285680175	456	0.932082086	0.238515235	normal	0.945730456	0.205626257	normal	0.933722144	0.235034693	normal	0.353036293	0.224935462	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc-finger domain;; Zinc-finger double domain"	Zinc finger protein 827 GN=ZNF827 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 827 isoform X2 [Tupaia chinensis]
ENSG00000151617(EDNRA)	--	0.485383157	22	0.30475691	19	0.207895587	10	0.738275107	45	0.889349004	55	0.589745377	37	0.737059596	0.954146826	normal	0.040649117	1.44172623	normal	0.072251514	1.734560231	normal	0.008480584	1.402971512	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04197|0|ptr:461530|EDNRA; endothelin receptor type A; K04197 endothelin receptor type A (A)	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Vascular smooth muscle contraction (ko04270);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Endothelin-1 receptor (Precursor) GN=EDNRA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endothelin-1 receptor isoform X1 [Eptesicus fuscus]
ENSG00000151623(NR3C2)	--	0.435046529	39	0.41029171	40	0.3627463	36	0.478454173	49	0.926957446	94	1.477087694	154	0.972505508	0.288325132	normal	0.016324733	1.181281248	normal	1.64E-10	2.043509413	up	0.1473735	1.350675092	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08555|0|hsa:4306|NR3C2, MCR, MLR, MR, NR3C2VIT; nuclear receptor subfamily 3, group C, member 2; K08555 mineralocorticoid receptor (A)"	Aldosterone-regulated sodium reabsorption (ko04960)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Mineralocorticoid receptor GN=NR3C2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mineralocorticoid receptor isoform X1 [Equus przewalskii] 
ENSG00000151632(AKR1C2)	--	167.6746336	3595	216.1071816	4710	163.4968335	3336	727.8116196	16015	889.8854657	20033	1261.971417	27441	0	2.124057862	up	0	2.066802967	up	0	3.031278173	up	2.19E-07	2.427279209	up	[R]	General function prediction only	--	"K00212|0|hsa:1645|AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB; aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112); K00089 3alpha-hydroxysteroid dehydrogenase (A-specific) [EC:1.1.1.213] K00212 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.20] (A)"	Steroid hormone biosynthesis (ko00140);; Metabolism of xenobiotics by cytochrome P450 (ko00980)	[R]	General function prediction only	Aldo/keto reductase family	Aldo-keto reductase family 1 member C2 GN=AKR1C2 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: aldo-keto reductase family 1 member C23-like [Equus caballus] 
ENSG00000151640(DPYSL4)	--	9.205970307	500	8.714965	483	9.325192035	523	11.90527868	654	10.269074	556	8.993816324	488	0.819119409	0.355572521	normal	0.953094436	0.181106288	normal	0.966403933	-0.107898178	normal	0.553535676	0.151139908	normal	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[F]	Nucleotide transport and metabolism	Amidohydrolase family;; Amidohydrolase;; Amidohydrolase;; Amidohydrolase family	Dihydropyrimidinase-related protein 4 GN=DPYSL4 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: dihydropyrimidinase-related protein 4 isoform X1 [Tupaia chinensis]
ENSG00000151651(ADAM8)	--	1.208208356	87	1.434317626	111	1.138155723	84	1.045959414	79	0.740220708	59	1.178727703	96	0.967407041	-0.166900244	normal	0.106455644	-0.915797354	normal	0.964515418	0.181298452	normal	0.575371615	-0.290226311	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K06540|0|hsa:101|ADAM8, CD156, CD156a, MS2; ADAM metallopeptidase domain 8 (EC:3.4.24.-); K06540 disintegrin and metalloproteinase domain-containing protein 8 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; Disintegrin;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; ADAM cysteine-rich	Disintegrin and metalloproteinase domain-containing protein 8 (Precursor) GN=ADAM8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 8 [Camelus ferus]
ENSG00000151655(ITIH2)	--	0.198652193	13	0.016538633	1	0.102143806	6	0.5656766	38	1.027687814	57	1.235435282	88	0.305198003	1.414903488	normal	2.43E-11	4.526978255	up	9.40E-14	3.567374768	up	0.000236382	3.175150021	up	[R]	General function prediction only	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Biological Process: hyaluronan metabolic process (GO:0030212);; 	--	--	--	--	Inter-alpha-trypsin inhibitor heavy chain C-terminus;; Vault protein inter-alpha-trypsin domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Inter-alpha-trypsin inhibitor heavy chain H2 (Precursor) GN=ITIH2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: inter-alpha-trypsin inhibitor heavy chain H2 isoform X1 [Tupaia chinensis] 
ENSG00000151657(KIN)	--	2.815934856	268	3.154351	298	3.25683455	313	2.197047	217	2.362903139	227	3.129134792	310	0.880463158	-0.333242425	normal	0.772387482	-0.411645011	normal	0.967869006	-0.022078693	normal	0.412563112	-0.241263496	normal	--	--	--	"K13102|0|ptg:102971593|KIN; KIN, antigenic determinant of recA protein homolog (mouse); K13102 DNA/RNA-binding protein KIN17 (A)"	--	[A]	RNA processing and modification	Domain of Kin17 curved DNA-binding protein	DNA/RNA-binding protein KIN17 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: DNA/RNA-binding protein KIN17 [Felis catus] 
ENSG00000151665(PIGF)	--	40.28141706	647	43.92236047	701	38.279006	602	34.139945	549	32.864782	525	41.296197	660	0.918357068	-0.267102283	normal	0.618523305	-0.437428982	normal	0.966944374	0.124113234	normal	0.402102147	-0.190252209	normal	--	--	--	"K05287|1.38772e-155|hsa:5281|PIGF; phosphatidylinositol glycan anchor biosynthesis, class F (EC:2.7.8.1); K05287 phosphatidylinositol glycan, class F [EC:2.7.-.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[MO]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	GPI biosynthesis protein family Pig-F	Phosphatidylinositol-glycan biosynthesis class F protein GN=PIGF OS=Homo sapiens (Human) PE=1 SV=1	MO	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: phosphatidylinositol-glycan biosynthesis class F protein [Pteropus alecto] 
ENSG00000151687(ANKAR)	--	0.71025868	41	0.691454515	37	0.850630697	50	0.321727472	18	0.280642757	17	0.599935252	33	0.546049917	-1.151593556	normal	0.712443393	-1.076966454	normal	0.92567401	-0.585794571	normal	0.102762644	-0.93140635	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Armadillo/beta-catenin-like repeat;; Ankyrin repeats (3 copies);; HEAT repeats;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin and armadillo repeat-containing protein GN=ANKAR OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: ankyrin and armadillo repeat-containing protein [Ceratotherium simum simum]
ENSG00000151689(INPP1)	--	5.887969	207	4.612129236	167	7.616595	238	10.950445	327	9.308932256	329	9.293281653	328	0.167477866	0.625107206	normal	0.000606396	0.95056871	normal	0.669106571	0.451986352	normal	0.003746072	0.664442325	normal	--	--	Biological Process: phosphatidylinositol phosphorylation (GO:0046854);; 	K01107|0|hsa:3628|INPP1; inositol polyphosphate-1-phosphatase (EC:3.1.3.57); K01107 inositol polyphosphate 1-phosphatase [EC:3.1.3.57] (A)	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[F]	Nucleotide transport and metabolism	Inositol monophosphatase family	Inositol polyphosphate 1-phosphatase GN=INPP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inositol polyphosphate 1-phosphatase [Galeopterus variegatus]
ENSG00000151690(MFSD6)	--	13.956098	1210	15.94411694	1380	14.59973426	1296	8.369304915	758	7.722583139	676	8.815938	801	0.005881842	-0.704428212	normal	2.18E-07	-1.049320292	down	0.00616887	-0.701431611	normal	1.20E-08	-0.81911459	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Major Facilitator Superfamily;; MFS_1 like family;; MFS/sugar transport protein;; Nucleoside H+ symporter;; LacY proton/sugar symporter	Major facilitator superfamily domain-containing protein 6 GN=MFSD6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: major facilitator superfamily domain-containing protein 6 [Equus caballus] 
ENSG00000151692(RNF144A)	--	7.259290002	700	6.095907999	587	6.889219116	651	5.451523739	432	4.887806288	424	3.54506881	329	0.007066432	-0.7251086	normal	0.451086074	-0.489232696	normal	1.00E-05	-0.989564024	normal	2.56E-05	-0.731550727	normal	--	--	--	"K11975|0|hsa:9781|RNF144A, RNF144, UBCE7IP4; ring finger protein 144A; K11975 E3 ubiquitin-protein ligase RNF144 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain	E3 ubiquitin-protein ligase RNF144A GN=RNF144A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase RNF144A isoform X4 [Canis lupus familiaris]
ENSG00000151693(ASAP2)	--	12.38253541	997	12.94290247	1061	12.599149	1037	12.966522	1065	9.10449932	750	8.122168	685	0.978336953	0.064259937	normal	0.27794423	-0.521000678	normal	0.062021885	-0.60543711	normal	0.193809064	-0.330663749	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	"K12488|0|ggo:101147540|ASAP2; arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform 1; K12488 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein (A)"	Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Variant SH3 domain;; PH domain;; SH3 domain;; Ankyrin repeats (many copies);; Variant SH3 domain;; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 GN=ASAP2 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 2 isoform 1 [Odobenus rosmarus divergens]"
ENSG00000151694(ADAM17)	--	26.30335179	2023	30.1863781	2337	27.09460895	2059	22.94750081	1778	22.72279145	1741	25.34691443	1944	0.966218896	-0.216897385	normal	0.618362946	-0.445832511	normal	0.984581085	-0.091138152	normal	0.136508185	-0.253725986	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K06059|0|ptr:459018|ADAM17; ADAM metallopeptidase domain 17; K06059 disintegrin and metalloproteinase domain-containing protein 17 [EC:3.4.24.86] (A)	Notch signaling pathway (ko04330);; Alzheimer's disease (ko05010)	[W]	Extracellular structures	Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Disintegrin;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12B Reprolysin-like;; Reprolysin family propeptide	Disintegrin and metalloproteinase domain-containing protein 17 (Precursor) GN=ADAM17 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: disintegrin and metalloproteinase domain-containing protein 17 isoform 1 [Ceratotherium simum simum]
ENSG00000151702(FLI1)	--	0.014945406	1	0	0	0.017885051	0	0	0	0.017355069	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09436|0|pps:100971241|FLI1; Fli-1 proto-oncogene, ETS transcription factor; K09436 friend leukemia integration 1 transcription factor (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	Friend leukemia integration 1 transcription factor GN=FLI1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: Friend leukemia integration 1 transcription factor isoform 1 [Ceratotherium simum simum]
ENSG00000151704(KCNJ1)	--	0.043792818	2	0.128400348	6	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04995|0|hsa:3758|KCNJ1, KIR1.1, ROMK, ROMK1; potassium inwardly-rectifying channel, subfamily J, member 1; K04995 potassium inwardly-rectifying channel subfamily J member 1 (A)"	Aldosterone-regulated sodium reabsorption (ko04960);; Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	ATP-sensitive inward rectifier potassium channel 1 GN=KCNJ1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: ATP-sensitive inward rectifier potassium channel 1 isoform 1 [Ceratotherium simum simum]
ENSG00000151715(TMEM45B)	--	0.120873008	3	0.149172201	5	0.08357839	2	0.040140289	1	0.039168638	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Family of unknown function (DUF716)	Transmembrane protein 45B GN=TMEM45B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 45B [Galeopterus variegatus]
ENSG00000151718(WWC2)	--	9.3695228	1009	9.550337926	1164	10.52014522	1241	9.369855597	1119	7.47181205	943	9.423718532	1171	0.974552819	0.118280527	normal	0.878978807	-0.324718247	normal	0.978649756	-0.091938126	normal	0.669140257	-0.09950558	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	WW domain	Protein WWC2 GN=WWC2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein WWC2 [Sus scrofa]
ENSG00000151725(CENPU)	--	11.8327	458	10.862501	410	14.2014	537	9.77513	383	10.255057	388	9.800834	379	0.902285573	-0.28777805	normal	0.964099504	-0.100612263	normal	0.37834042	-0.509299544	normal	0.171211868	-0.309728475	normal	--	--	--	"K11513|0|hsa:79682|CENPU, CENP50, CENPU50, KLIP1, MLF1IP, PBIP1; centromere protein U; K11513 centromere protein U (A)"	--	--	--	CENP-A nucleosome associated complex (NAC) subunit	Centromere protein U GN=CENPU OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: centromere protein U isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000151726(ACSL1)	--	15.69540495	993	12.35582981	878	11.46570322	801	9.769851401	700	10.84307177	757	13.91693386	983	0.214944154	-0.53428085	normal	0.941676952	-0.234917959	normal	0.911319386	0.286608468	normal	0.633308535	-0.151455448	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01897|0|hsa:2180|ACSL1, ACS1, FACL1, FACL2, LACS, LACS1, LACS2; acyl-CoA synthetase long-chain family member 1 (EC:6.2.1.3); K01897 long-chain acyl-CoA synthetase [EC:6.2.1.3] (A)"	Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	AMP-binding enzyme	Long-chain-fatty-acid--CoA ligase 1 GN=ACSL1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: long-chain-fatty-acid--CoA ligase 1 isoform X2 [Tupaia chinensis]
ENSG00000151729(SLC25A4)	--	13.28157824	275	12.46073206	290	14.78063433	323	12.2452851	292	13.42459349	291	13.59182971	310	0.966242567	0.055404078	normal	0.966579257	-0.016375061	normal	0.966177478	-0.067236031	normal	0.983948554	-0.012681786	normal	--	--	--	"K05863|0|pon:100437258|SLC25A4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Parkinson's disease (ko05012);; Huntington's disease (ko05016);; HTLV-I infection (ko05166)	[C]	Energy production and conversion	Mitochondrial carrier protein	ADP/ATP translocase 1 GN=SLC25A4 OS=Homo sapiens (Human) PE=1 SV=4	C	Energy production and conversion	PREDICTED: ADP/ATP translocase 1 [Galeopterus variegatus]
ENSG00000151743(AMN1)	--	11.55405087	268	8.121975813	203	8.116903657	205	5.9596695	118	6.4297315	129	5.820873919	142	5.84E-06	-1.203575834	down	0.23441625	-0.66922508	normal	0.593019376	-0.533270753	normal	0.002345144	-0.818057738	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Protein AMN1 homolog GN=AMN1 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: protein AMN1 homolog isoform X1 [Galeopterus variegatus]
ENSG00000151746(BICD1)	--	7.85621	524	8.056000749	563	10.236988	661	7.259548725	629	5.740144389	510	6.606897632	512	0.937225591	0.232039299	normal	0.957543833	-0.163602271	normal	0.780706876	-0.375818183	normal	0.710108451	-0.103907235	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; Biological Process: transport (GO:0006810);; 	K18739|0|mcf:102119076|BICD1; bicaudal D homolog 1 (Drosophila); K18739 protein bicaudal D (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Microtubule-associated protein Bicaudal-D	Protein bicaudal D homolog 1 GN=BICD1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein bicaudal D homolog 1 isoform 1 [Ceratotherium simum simum]
ENSG00000151748(SAV1)	--	10.92458	436	14.31488	553	10.403217	477	17.17546101	671	14.00165003	588	18.10039704	827	0.114632807	0.589466307	normal	0.970476659	0.066932596	normal	0.001382087	0.783696348	normal	0.055252262	0.488125313	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K16686|0|hsa:60485|SAV1, SAV, WW45, WWP4; salvador family WW domain containing protein 1; K16686 scaffold protein salvador (A)"	Hippo signaling pathway (ko04390)	[R]	General function prediction only	WW domain	Protein salvador homolog 1 GN=SAV1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein salvador homolog 1 [Mustela putorius furo] 
ENSG00000151773(CCDC122)	--	2.954729	72	2.290424	66	2.961655	74	2.549264	58	1.723119	42	2.875809	65	0.954443484	-0.334798547	normal	0.830415356	-0.65454148	normal	0.968620514	-0.191204685	normal	0.493909195	-0.382425945	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 122 GN=CCDC122 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 122 [Ceratotherium simum simum]
ENSG00000151779(NBAS)	--	10.28123472	1219	10.39238309	1242	11.04898438	1364	8.555244189	1073	8.7510559	1119	7.711783095	1033	0.956396322	-0.214591768	normal	0.967918005	-0.171661364	normal	0.699601583	-0.408772305	normal	0.126856085	-0.267244688	normal	--	--	"Biological Process: retrograde vesicle-mediated transport, Golgi to ER (GO:0006890);; "	--	--	[S]	Function unknown	"Neuroblastoma-amplified sequence, N terminal;; Secretory pathway protein Sec39"	Neuroblastoma-amplified sequence GN=NBAS OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: neuroblastoma-amplified sequence [Equus caballus]
ENSG00000151789(ZNF385D)	--	0.0237246	4	0.0177683	3	0.00593927	0	0.0352589	6	0.0171553	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; A-kinase anchoring protein 95 (AKAP95);; U1 zinc finger	Zinc finger protein 385D GN=ZNF385D OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 385D-like [Sorex araneus]
ENSG00000151790(TDO2)	--	0.512985562	11	0.483286267	16	0.708818219	21	0.870267238	26	1.415541341	30	1.757962309	45	0.885489667	1.107130049	normal	0.92947482	0.827559754	normal	0.624076568	1.039021063	normal	0.088810939	1.054480075	normal	[E]	Amino acid transport and metabolism	"Molecular Function: tryptophan 2,3-dioxygenase activity (GO:0004833);; Biological Process: tryptophan catabolic process to kynurenine (GO:0019441);; Molecular Function: heme binding (GO:0020037);; "	"K00453|0|pps:100984006|TDO2; tryptophan 2,3-dioxygenase; K00453 tryptophan 2,3-dioxygenase [EC:1.13.11.11] (A)"	Tryptophan metabolism (ko00380)	[E]	Amino acid transport and metabolism	"Tryptophan 2,3-dioxygenase"	"Tryptophan 2,3-dioxygenase {ECO:0000255|HAMAP-Rule:MF_03020} OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: tryptophan 2,3-dioxygenase [Chrysochloris asiatica]"
ENSG00000151806(GUF1)	--	8.150545	618	8.081319	614	8.116725515	602	8.81792	676	8.514727	651	8.131999	618	0.970071526	0.098350318	normal	0.971925542	0.062842004	normal	0.973569101	0.029478819	normal	0.832164389	0.063282035	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; GTP-binding protein LepA C-terminus;; Elongation factor G C-terminus;; Elongation factor Tu domain 2;; 50S ribosome-binding GTPase;; Ras family;; Signal recognition particle receptor beta subunit	"Translation factor GUF1, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03137} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: translation factor GUF1, mitochondrial [Galeopterus variegatus]"
ENSG00000151835(SACS)	--	8.519136109	2199	8.347888006	2195	8.32727014	2175	10.64246648	2906	9.147668507	2490	7.32291172	1985	0.847719354	0.371128651	normal	0.980243932	0.16039444	normal	0.981256864	-0.140065853	normal	0.595411495	0.14580511	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17592|0|ggo:101134889|SACS; sacsin; K17592 sacsin (A)	--	--	--	"HEPN domain;; Ubiquitin family;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	Sacsin GN=SACS OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sacsin [Tupaia chinensis]
ENSG00000151838(CCDC175)	--	0.0515407	3	0.104212	6	0.0345705	1	0.0512248	3	0.0175393	0	0.102225	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 175 GN=CCDC175 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 175 [Galeopterus variegatus]
ENSG00000151849(CENPJ)	--	4.729335281	496	4.967879489	495	5.786818143	623	3.7895314	395	3.458399887	335	3.44717736	381	0.820704728	-0.358073641	normal	0.179499645	-0.582516016	normal	0.011004661	-0.715488876	normal	0.003315962	-0.559728511	normal	--	--	--	"K11502|0|hsa:55835|CENPJ, BM032, CENP-J, CPAP, LAP, LIP1, MCPH6, SASS4, SCKL4, Sas-4; centromere protein J; K11502 centromere protein J (A)"	--	--	--	T-complex protein 10 C-terminus	Centromere protein J GN=CENPJ OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centromere protein J [Leptonychotes weddellii]
ENSG00000151876(FBXO4)	--	4.189557	105	5.267649	128	4.1862738	105	7.048838	175	7.263011	182	5.558286	138	0.244112192	0.698143059	normal	0.746058733	0.4815745	normal	0.89787229	0.381184675	normal	0.1178487	0.528386824	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10291|0|pps:100979662|FBXO4; F-box protein 4; K10291 F-box protein 4 (A)	Ubiquitin mediated proteolysis (ko04120)	--	--	F-box-like;; F-box domain	F-box only protein 4 GN=FBXO4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box only protein 4 isoform X1 [Pteropus alecto] 
ENSG00000151881(TMEM267)	--	13.27416874	367	13.90443803	407	15.18467159	366	12.25416787	348	13.57981907	342	14.43334993	398	0.963436003	-0.107064631	normal	0.914250342	-0.271357501	normal	0.963416498	0.112188699	normal	0.794298891	-0.088282158	normal	--	--	--	--	--	--	--	--	Transmembrane protein C5orf28 GN=C5orf28 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein C5orf28 homolog [Loxodonta africana] 
ENSG00000151882(CCL28)	--	0	0	0	0	0.02188881	0	0.417299729	13	0.16664964	7	0.148578828	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	K05513|1.7744e-73|ggo:101139674|CCL28; c-C motif chemokine 28; K05513 C-C motif chemokine 28 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Intestinal immune network for IgA production (ko04672)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	C-C motif chemokine 28 (Precursor) GN=CCL28 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	C-C motif chemokine 28 precursor [Sus scrofa] 
ENSG00000151883(PARP8)	--	2.130622411	98	1.746400199	119	5.107895569	99	2.450602841	88	1.595002601	70	1.863208385	75	0.963984485	-0.183079539	normal	0.29148847	-0.773982753	normal	0.91724353	-0.40175564	normal	0.288529096	-0.46156766	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15258|0|hsa:79668|PARP8, ARTD16, pART16; poly (ADP-ribose) polymerase family, member 8 (EC:2.4.2.30); K15258 poly [ADP-ribose] polymerase 6/8 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain	Poly [ADP-ribose] polymerase 8 GN=PARP8 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: poly [ADP-ribose] polymerase 8-like isoform 1 [Odobenus rosmarus divergens] 
ENSG00000151892(GFRA1)	--	2.098572609	296	2.76342505	460	3.061649003	375	4.717112211	616	3.69423	530	4.984918099	723	5.24E-06	1.0227435	up	0.952236562	0.182373013	normal	3.29E-05	0.93604707	normal	0.008049655	0.703790814	normal	--	--	--	--	--	--	--	GDNF/GAS1 domain	GDNF family receptor alpha-1 (Precursor) GN=GFRA1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: GDNF family receptor alpha-1 isoform X1 [Myotis lucifugus]
ENSG00000151893(CACUL1)	--	6.973432073	1300	7.550121641	1404	7.245595304	1330	8.560511929	1609	7.706559356	1438	7.605300376	1422	0.932640777	0.276526232	normal	0.983025521	0.013080261	normal	0.980522992	0.088106875	normal	0.55243967	0.126101364	normal	--	--	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cullin family	CDK2-associated and cullin domain-containing protein 1 GN=CACUL1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: CDK2-associated and cullin domain-containing protein 1-like [Tupaia chinensis]
ENSG00000151914(DST)	--	17.57643447	6121	21.89055049	7201	21.72200539	7127	25.35829989	9297	20.45058971	7566	21.23477348	8067	0.181262246	0.572048352	normal	0.994755738	0.049896728	normal	0.991332126	0.170411882	normal	0.149063632	0.26423792	normal	[Z]	Cytoskeleton	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoskeleton (GO:0005856);; Molecular Function: microtubule binding (GO:0008017);; 	K10382|0|hgl:101717284|dystonin-like; K10382 dystonin (A)	--	[Z]	Cytoskeleton	Spectrin repeat;; Plectin repeat;; Calponin homology (CH) domain;; Growth-Arrest-Specific Protein 2 Domain;; EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair;; CAMSAP CH domain	Dystonin GN=DST OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: dystonin isoform X13 [Bos taurus]
ENSG00000151917(BEND6)	--	0.503752557	25	0.410775825	23	0.402229647	23	1.231832001	66	0.8449992	43	1.013321959	53	0.037602421	1.318101229	normal	0.841028807	0.840296916	normal	0.306823655	1.145155659	normal	0.021502562	1.167972497	normal	--	--	--	--	--	--	--	BEN domain	BEN domain-containing protein 6 GN=BEND6 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: BEN domain-containing protein 6 isoform X1 [Leptonychotes weddellii]
ENSG00000151923(TIAL1)	--	38.96263586	1543	45.1012875	1742	47.69499201	1809	44.65780229	1720	50.0584127	1854	46.142515	1840	0.979551185	0.125719637	normal	0.98417211	0.068412489	normal	0.985957939	0.016208481	normal	0.787087247	0.067085818	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13201|0|umr:103657729|TIAL1; TIA1 cytotoxic granule-associated RNA binding protein-like 1; K13201 nucleolysin TIA-1/TIAR (A)	--	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Calcipressin"	Nucleolysin TIAR GN=TIAL1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: nucleolysin TIAR isoform 1 [Trichechus manatus latirostris]
ENSG00000151929(BAG3)	--	31.7430482	1738	32.855469	1766	40.787901	2219	38.6573654	2090	33.43823955	1830	30.02108614	1662	0.960626876	0.235052904	normal	0.985263225	0.02990659	normal	0.675764852	-0.424944882	normal	0.856106482	-0.057454296	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Molecular Function: chaperone binding (GO:0051087);; 	"K09557|0|hsa:9531|BAG3, BAG-3, BIS, CAIR-1, MFM6; BCL2-associated athanogene 3; K09557 BCL2-associated athanogene 3 (A)"	--	[T]	Signal transduction mechanisms	BAG domain;; WW domain	BAG family molecular chaperone regulator 3 GN=BAG3 OS=Homo sapiens (Human) PE=1 SV=3	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: BAG family molecular chaperone regulator 3 [Ceratotherium simum simum]
ENSG00000151967(SCHIP1)	--	8.093963982	324	12.443667	435	11.93896087	430	11.12039079	424	10.20609976	391	14.73064019	579	0.832086201	0.35575975	normal	0.952491576	-0.174632613	normal	0.678073962	0.419658849	normal	0.611813597	0.209367137	normal	--	--	--	--	--	[R]	General function prediction only	Schwannomin-interacting protein 1	Schwannomin-interacting protein 1 GN=SCHIP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: schwannomin-interacting protein 1 isoform X5 [Sus scrofa] 
ENSG00000152049(KCNE4)	--	0.138667	8	0.0171216	1	0.0169163	0	0.585547	34	0.370422	21	0.274761	16	0.066829633	1.870091973	normal	0.015703412	3.149394022	normal	--	--	--	--	--	--	--	--	Molecular Function: voltage-gated potassium channel activity (GO:0005249);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	"K04898|9.48671e-128|hsa:23704|KCNE4, MIRP3; potassium voltage-gated channel, Isk-related family, member 4; K04898 potassium voltage-gated channel Isk-related subfamily E member 4 (A)"	--	--	--	Slow voltage-gated potassium channel	Potassium voltage-gated channel subfamily E member 4 GN=KCNE4 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: potassium voltage-gated channel subfamily E member 4 [Ochotona princeps]
ENSG00000152056(AP1S3)	--	14.098108	770	11.176231	696	12.860337	764	21.989991	1355	18.4987	1082	15.77319014	1030	0.00069815	0.783337464	normal	0.059534589	0.614036597	normal	0.648611747	0.421986392	normal	0.000500899	0.614647932	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K12395|2.11828e-99|ptr:459979|AP1S3; adaptor-related protein complex 1, sigma 3 subunit; K12395 AP-1 complex subunit sigma-3 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	AP-1 complex subunit sigma-3 GN=AP1S3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-1 complex subunit sigma-3 [Bubalus bubalis]
ENSG00000152061(RABGAP1L)	--	6.601742298	503	6.537897545	480	6.531528944	470	5.15055327	331	6.620402699	477	5.0135012	364	0.074947799	-0.632160062	normal	0.970190885	-0.030375696	normal	0.794326224	-0.375636453	normal	0.133152099	-0.330893155	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; Kinesin protein;; Phosphotyrosine interaction domain (PTB/PID)	Rab GTPase-activating protein 1-like OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"PREDICTED: rab GTPase-activating protein 1-like, isoform 10-like isoform 1 [Ceratotherium simum simum]"
ENSG00000152076(CCDC74B)	--	6.206385254	146	6.791480098	144	5.258407034	121	1.641361342	42	3.066095783	64	2.5088804	61	2.75E-08	-1.790902825	down	0.001097847	-1.172371456	down	0.038182079	-0.978854718	normal	7.88E-05	-1.31963107	down	--	--	--	--	--	--	--	"Coiled coil protein 74, C terminal;; Coiled-coil domain of unknown function"	Coiled-coil domain-containing protein 74B GN=CCDC74B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: coiled-coil domain-containing protein 74B-like, partial [Equus przewalskii]"
ENSG00000152082(MZT2B)	--	192.34263	2036	176.46205	2022	193.06607	2271	150.419302	1717	144.32951	1587	150.5543	1715	0.940784848	-0.276452269	normal	0.832410364	-0.370593712	normal	0.71928822	-0.413092941	normal	0.02274069	-0.355597526	normal	--	--	--	K16574|5.02782e-89|mcf:102146666|MZT2B; mitotic spindle organizing protein 2B; K16574 mitotic-spindle organizing protein 2A/2B (A)	--	--	--	Mitotic-spindle organizing gamma-tubulin ring associated	Mitotic-spindle organizing protein 2B GN=MZT2B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitotic-spindle organizing protein 2B isoform X1 [Myotis lucifugus]
ENSG00000152086(TUBA3E)	--	0.0341271	1	0	0	0.132305	3	0	0	0.0331136	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07374|0|hsa:112714|TUBA3E; tubulin, alpha 3e; K07374 tubulin alpha (A)"	Phagosome (ko04145);; Gap junction (ko04540);; Pathogenic Escherichia coli infection (ko05130)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha-3E chain GN=TUBA3E OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	Tubulin alpha-3 chain [Myotis davidii]
ENSG00000152102(FAM168B)	--	42.88465872	3682	54.13861	3955	39.48801965	3393	33.06178	2758	39.37873	3117	36.205577	2815	0.640395187	-0.447482823	normal	0.887105634	-0.364788562	normal	0.955596825	-0.277581911	normal	0.019529334	-0.365295049	normal	--	--	--	--	--	--	--	Tongue Cancer Chemotherapy Resistant Protein 1	Myelin-associated neurite-outgrowth inhibitor GN=FAM168B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: myelin-associated neurite-outgrowth inhibitor [Camelus ferus] 
ENSG00000152104(PTPN14)	--	7.513849976	1851	7.922792581	1945	9.461362891	2312	12.16276414	2976	9.987469743	2453	9.66833249	2371	0.016735623	0.653805708	normal	0.921259935	0.313133303	normal	0.988089681	0.028044708	normal	0.076812381	0.331190343	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18025|0|hsa:5784|PTPN14, PEZ, PTP36; protein tyrosine phosphatase, non-receptor type 14 (EC:3.1.3.48); K18025 tyrosine-protein phosphatase non-receptor type 14/21 [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; FERM central domain;; FERM N-terminal domain;; FERM C-terminal PH-like domain;; Dual specificity phosphatase, catalytic domain"	Tyrosine-protein phosphatase non-receptor type 14 GN=PTPN14 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 14 [Ceratotherium simum simum]
ENSG00000152127(MGAT5)	--	12.001522	1941	10.31663955	1694	11.62821314	1877	8.0711547	1311	7.3103291	1176	6.802442	1092	0.062046503	-0.596386196	normal	0.182636813	-0.547382368	normal	0.000441321	-0.788903492	normal	5.22E-06	-0.644689397	normal	--	--	--	"K00744|0|ptr:459625|MGAT5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; K00744 alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155] (A)"	N-Glycan biosynthesis (ko00510)	--	--	Glycosyltransferase family 18;; Domain of unknown function (DUF4525)	"Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A GN=MGAT5 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A [Felis catus] "
ENSG00000152128(TMEM163)	--	0.0740542	2	0	0	0.0359206	0	0.145905	4	0.46566	12	0.218731	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 163 GN=TMEM163 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 163 [Chrysochloris asiatica]
ENSG00000152133(GPATCH11)	--	4.538617	333	4.565449	332	5.559609	400	4.488183	329	4.588265	329	4.83361	357	0.967329183	-0.048043839	normal	0.966926395	-0.034364968	normal	0.953507837	-0.171679913	normal	0.79471399	-0.089985104	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	Domain of unknown function (DUF4187);; G-patch domain;; DExH-box splicing factor binding site	G patch domain-containing protein 11 GN=GPATCH11 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: G patch domain-containing protein 11 isoform X2 [Equus caballus] 
ENSG00000152137(HSPB8)	--	10.0351	371	11.5085	427	11.0194	408	21.636854	790	16.6692	612	19.4465	720	6.85E-07	1.056535377	up	0.421921493	0.49639332	normal	0.000969818	0.808849779	normal	2.62E-06	0.793617948	normal	--	--	--	K08879|1.26925e-127|ptr:452295|HSPB8; heat shock 22kDa protein 8; K08879 heat shock protein beta-8 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp20/alpha crystallin family	Heat shock protein beta-8 GN=HSPB8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein beta-8 [Trichechus manatus latirostris]
ENSG00000152147(GEMIN6)	--	18.35138941	587	16.911128	563	18.05391999	538	13.07682121	447	10.41610929	409	10.77685035	389	0.66520997	-0.422645729	normal	0.487409092	-0.480937968	normal	0.504960319	-0.47455164	normal	0.01750989	-0.460900353	normal	--	--	Biological Process: spliceosomal complex assembly (GO:0000245);; Cellular Component: nucleus (GO:0005634);; 	K13134|6.41007e-122|ptr:459168|GEMIN6; gem (nuclear organelle) associated protein 6; K13134 gem associated protein 6 (A)	RNA transport (ko03013)	--	--	Gemin6 protein	Gem-associated protein 6 GN=GEMIN6 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: gem-associated protein 6 [Galeopterus variegatus]
ENSG00000152154(TMEM178A)	--	0.39013439	9	0.77313942	18	0.335864483	7	0.2382673	5	0.544817231	12	0.128856465	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin tight junction	Transmembrane protein 178A (Precursor) GN=TMEM178A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 178A [Leptonychotes weddellii]
ENSG00000152192(POU4F1)	--	1.7339	134	1.4286	112	1.78046	139	1.25005	97	1.65205	127	1.56679	122	0.80571358	-0.490368512	normal	0.960640167	0.157900067	normal	0.956226279	-0.194237784	normal	0.72414429	-0.174274198	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09366|0|hsa:5457|POU4F1, BRN3A, Oct-T1, RDC-1, brn-3A; POU class 4 homeobox 1; K09366 POU domain transcription factor, class 4 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 4, transcription factor 1 GN=POU4F1 OS=Homo sapiens (Human) PE=2 SV=4"	K	Transcription	"PREDICTED: POU domain, class 4, transcription factor 1 [Chrysochloris asiatica]"
ENSG00000152193(RNF219)	--	6.32003	383	5.78296	348	6.52582	385	6.57846	401	6.39725	387	5.18004	313	0.968975515	0.035287237	normal	0.959703695	0.131278548	normal	0.890891213	-0.305653184	normal	0.916365523	-0.041285708	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 219 GN=RNF219 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 219 [Ceratotherium simum simum]
ENSG00000152208(GRID2)	--	0.054550486	5	0.00986429	1	0	0	0	0	0.04036943	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05207|0|ptr:743067|GRID2; glutamate receptor, ionotropic, delta 2; K05207 glutamate receptor delta-2 subunit (A)"	Neuroactive ligand-receptor interaction (ko04080);; Long-term depression (ko04730)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Receptor family ligand binding region;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site"	"Glutamate receptor ionotropic, delta-2 (Precursor) GN=GRID2 OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	PREDICTED: glutamate receptor delta-2 subunit [Ovis aries] 
ENSG00000152217(SETBP1)	--	0.6238629	67	0.485700032	59	0.2061502	45	0.574958798	127	0.687993858	154	0.565544993	127	0.103301791	0.876931498	normal	5.45E-05	1.340673889	up	4.22E-05	1.458114627	up	0.000258783	1.23295148	up	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	--	SET-binding protein GN=SETBP1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: SET-binding protein isoform X1 [Equus caballus]
ENSG00000152219(ARL14EP)	--	11.932908	494	16.323914	624	15.089418	570	12.113327	489	11.5944198	511	12.44763	470	0.970647256	-0.045367019	normal	0.884335672	-0.308820675	normal	0.90404659	-0.285756324	normal	0.339467893	-0.220783311	normal	--	--	--	--	--	[S]	Function unknown	ARF7 effector protein C-terminus	ARL14 effector protein GN=ARL14EP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ARL14 effector protein isoform X2 [Oryctolagus cuniculus] 
ENSG00000152223(EPG5)	--	5.637999103	879	6.589682753	1016	5.158916173	1022	5.678977865	960	5.26049072	849	6.985773266	1225	0.974746207	0.096178087	normal	0.918534626	-0.280033818	normal	0.939887926	0.25275306	normal	0.93492335	0.03633933	normal	--	--	--	--	--	[S]	Function unknown	--	Ectopic P granules protein 5 homolog GN=EPG5 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: ectopic P granules protein 5 homolog [Equus caballus]
ENSG00000152229(PSTPIP2)	--	0	0	0	0	0	0	0.056181032	3	0.091134706	4	0.092990407	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Fes/CIP4, and EFC/F-BAR homology domain"	Proline-serine-threonine phosphatase-interacting protein 2 GN=PSTPIP2 OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: proline-serine-threonine phosphatase-interacting protein 2 [Tupaia chinensis]
ENSG00000152234(ATP5A1)	--	215.2445116	6064	200.551037	5925	198.045799	5643	216.778526	6314	219.6065337	6199	191.147261	5434	0.994383575	0.027445429	normal	0.993929975	0.043782867	normal	0.993406055	-0.062722096	normal	0.990690818	0.003837454	normal	[C]	Energy production and conversion	Molecular Function: ATP binding (GO:0005524);; Biological Process: ATP synthesis coupled proton transport (GO:0015986);; Biological Process: proton transport (GO:0015992);; Biological Process: ATP metabolic process (GO:0046034);; 	"K02132|0|ptr:455397|ATP5A1; ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle; K02132 F-type H+-transporting ATPase subunit alpha (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"ATP synthase alpha/beta family, nucleotide-binding domain;; ATP synthase alpha/beta chain, C terminal domain;; ATP synthase alpha/beta family, beta-barrel domain"	"ATP synthase subunit alpha, mitochondrial (Precursor) GN=ATP5A1 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: ATP synthase subunit alpha, mitochondrial [Pteropus alecto] "
ENSG00000152240(HAUS1)	--	18.471447	335	18.328728	329	25.07307292	401	24.537186	458	21.739248	389	16.503193	295	0.703012277	0.418706155	normal	0.938796587	0.219327982	normal	0.637656386	-0.449195654	normal	0.853525777	0.078583481	normal	--	--	--	"K16584|0|ptr:739317|HAUS1, CCDC5; HAUS augmin-like complex, subunit 1; K16584 HAUS augmin-like complex subunit 1 (A)"	--	--	--	--	HAUS augmin-like complex subunit 1 GN=HAUS1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: HAUS augmin-like complex subunit 1 isoform 1 [Ceratotherium simum simum]
ENSG00000152242(C18orf25)	--	7.2569295	567	7.480866	580	6.216386	493	9.4214632	693	11.06180075	838	7.8503482	592	0.924775757	0.258041051	normal	0.34172754	0.508362364	normal	0.925195228	0.255003328	normal	0.150883387	0.350656861	normal	--	--	--	--	--	--	--	E3 ubiquitin-protein ligase Arkadia N-terminus	Uncharacterized protein C18orf25 GN=C18orf25 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C18orf25 homolog isoform 1 [Odobenus rosmarus divergens]
ENSG00000152253(SPC25)	--	17.680489	359	18.0787039	370	22.85984687	463	10.177301	211	10.437862	212	8.897847	183	0.008090006	-0.793089882	normal	0.005062684	-0.820397892	normal	2.00E-09	-1.340243826	down	1.06E-06	-0.997127833	normal	--	--	--	"K11550|1.01824e-161|mcf:102133152|SPC25; SPC25, NDC80 kinetochore complex component; K11550 kinetochore protein Spc25, animal type (A)"	--	[S]	Function unknown	Chromosome segregation protein Spc25	Kinetochore protein Spc25 GN=SPC25 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: kinetochore protein Spc25 [Ceratotherium simum simum]
ENSG00000152256(PDK1)	--	6.088775395	437	6.70663318	632	4.96730225	431	4.930895699	356	1.74539037	203	3.858088173	304	0.868312694	-0.325318416	normal	2.78E-15	-1.65250683	down	0.423693327	-0.509767138	normal	0.031297005	-0.819939103	normal	[T]	Signal transduction mechanisms	--	"K12077|0|hsa:5163|PDK1; pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2); K12077 pyruvate dehydrogenase kinase isoform 1 [EC:2.7.11.2] (A)"	HIF-1 signaling pathway (ko04066);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	"Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Precursor) GN=PDK1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial isoform X2 [Felis catus]"
ENSG00000152270(PDE3B)	--	2.308255414	220	3.035632732	287	3.111003905	294	1.997715539	190	1.805102344	169	1.45828094	139	0.937409217	-0.240526779	normal	0.022765473	-0.780032437	normal	5.21E-05	-1.080747425	down	0.004686425	-0.707547814	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13296|0|hsa:5140|PDE3B, HcGIP1, cGIPDE1; phosphodiesterase 3B, cGMP-inhibited (EC:3.1.4.17); K13296 cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:3.1.4.17] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Morphine addiction (ko05032)	--	--	3'5'-cyclic nucleotide phosphodiesterase	"cGMP-inhibited 3',5'-cyclic phosphodiesterase B GN=PDE3B OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: cGMP-inhibited 3',5'-cyclic phosphodiesterase B [Odobenus rosmarus divergens]"
ENSG00000152284(TCF7L1)	--	4.5432031	258	3.859370019	223	4.115587616	203	2.597312065	129	2.570830062	150	1.676571392	91	0.00035351	-1.022043856	down	0.404279141	-0.588607065	normal	0.000136725	-1.152663632	down	0.000620523	-0.908697951	normal	--	--	--	"K04490|0|hsa:83439|TCF7L1, TCF-3, TCF3; transcription factor 7-like 1 (T-cell specific, HMG-box); K04490 transcription factor 7-like 1 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Melanogenesis (ko04916);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Basal cell carcinoma (ko05217);; Acute myeloid leukemia (ko05221);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[K]	Transcription	N-terminal CTNNB1 binding;; HMG (high mobility group) box;; HMG-box domain	Transcription factor 7-like 1 GN=TCF7L1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor 7-like 1 [Canis lupus familiaris]
ENSG00000152291(TGOLN2)	--	97.864565	11317	88.6129	10310	91.229605	10500	70.954694	8237	68.97048	7903	64.31317533	7365	0.622297223	-0.489054741	normal	0.891262491	-0.404930516	normal	0.445227959	-0.51983346	normal	0.003634712	-0.472369436	normal	--	--	--	--	--	--	--	--	Trans-Golgi network integral membrane protein 2 (Precursor) GN=TGOLN2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trans-Golgi network integral membrane protein 2-like [Pteropus alecto]
ENSG00000152292(SH2D6)	--	0.0721575	3	0.0470664	2	0.254234	10	0.0717875	3	0.0468702	1	0.0948353	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SH2 domain	SH2 domain-containing protein 6 GN=SH2D6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SH2 domain-containing protein 6 [Physeter catodon]
ENSG00000152332(UHMK1)	--	28.64607588	3298	32.8562861	3790	33.11286662	3732	33.23656355	3869	27.6021354	3172	30.879659	3554	0.980823144	0.199451213	normal	0.959303997	-0.278110149	normal	0.990423625	-0.078764037	normal	0.843370735	-0.051785428	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08877|0|rno:246332|Uhmk1, KIS, Kist; U2AF homology motif (UHM) kinase 1 (EC:2.7.11.1); K08877 U2AF homology motif (UHM) kinase 1 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	"Protein kinase domain;; Protein tyrosine kinase;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Kinase-like"	Serine/threonine-protein kinase Kist GN=UHMK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Kist [Oryctolagus cuniculus] 
ENSG00000152348(ATG10)	--	18.18495671	341	15.19676869	345	14.60242465	326	14.86804402	320	12.39447525	263	13.77718326	281	0.961244317	-0.121964666	normal	0.755726482	-0.41089032	normal	0.939301848	-0.221485524	normal	0.368620768	-0.249861968	normal	--	--	--	"K17888|8.72966e-166|hsa:83734|ATG10, APG10, APG10L, pp12616; autophagy related 10; K17888 ubiquitin-like-conjugating enzyme ATG10, animal type [EC:6.3.2.19] (A)"	Regulation of autophagy (ko04140)	[S]	Function unknown	"Autophagocytosis associated protein, active-site domain"	Ubiquitin-like-conjugating enzyme ATG10 GN=ATG10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ubiquitin-like-conjugating enzyme ATG10 [Trichechus manatus latirostris]
ENSG00000152359(POC5)	--	8.252592684	205	5.65547131	193	6.990587277	181	5.4502337	175	6.36557944	200	6.41916586	207	0.933473458	-0.257013703	normal	0.965508081	0.02974365	normal	0.952439646	0.183911784	normal	0.98564369	-0.013355615	normal	--	--	--	"K16483|0|hsa:134359|POC5, C5orf37; POC5 centriolar protein; K16483 centrosomal protein POC5 (A)"	--	--	--	--	Centrosomal protein POC5 GN=POC5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein POC5 isoform X2 [Canis lupus familiaris]
ENSG00000152377(SPOCK1)	--	12.40334434	610	11.15220419	480	10.74154043	637	10.107369	850	18.79158064	1035	12.76750743	719	0.561481906	0.446864058	normal	1.59E-07	1.084715416	up	0.960703707	0.166035729	normal	0.030388879	0.571292692	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	"K08136|0|hsa:6695|SPOCK1, SPOCK, TESTICAN, TIC1; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1; K08136 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) (A)"	--	[R]	General function prediction only	Secreted protein acidic and rich in cysteine Ca binding region;; Thyroglobulin type-1 repeat;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Testican-1 (Precursor) GN=SPOCK1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: testican-1 isoform X1 [Equus caballus] 
ENSG00000152380(FAM151B)	--	0.484728848	11	0.395283827	9	0.625689619	15	0.479916	12	0.659776286	15	0.804324351	20	--	--	--	--	--	--	0.986502376	0.374000628	normal	--	--	--	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2181)	Protein FAM151B GN=FAM151B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM151B isoform X1 [Mustela putorius furo]
ENSG00000152382(TADA1)	--	8.99983	305	8.15225	276	6.46559	216	8.45101	288	8.42703	284	8.40051	285	0.961898516	-0.112986833	normal	0.966354866	0.019689751	normal	0.814215116	0.389259372	normal	0.830845173	0.083015603	normal	--	--	Cellular Component: SAGA-type complex (GO:0070461);; 	"K11317|0|ptr:457482|TADA1, TADA1L; transcriptional adaptor 1; K11317 transcriptional adapter 1 (A)"	--	--	--	"Transcriptional regulator of RNA polII, SAGA, subunit"	Transcriptional adapter 1 GN=TADA1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcriptional adapter 1 [Canis lupus familiaris]
ENSG00000152402(GUCY1A2)	--	2.756926473	467	3.015952033	621	2.340104843	460	0.203992858	24	0.252362692	48	0.31800809	53	0	-4.227384292	down	0	-3.673317085	down	0	-3.089878518	down	1.40E-27	-3.649705585	down	[T]	Signal transduction mechanisms	Molecular Function: guanylate cyclase activity (GO:0004383);; Biological Process: cGMP biosynthetic process (GO:0006182);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Molecular Function: heme binding (GO:0020037);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12318|0|mcf:102127299|GUCY1A2; guanylate cyclase 1, soluble, alpha 2; K12318 guanylate cyclase soluble subunit alpha [EC:4.6.1.2] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term depression (ko04730);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970)	[F]	Nucleotide transport and metabolism	Heme NO binding associated;; Adenylate and Guanylate cyclase catalytic domain;; Heme NO binding	Guanylate cyclase soluble subunit alpha-2 GN=GUCY1A2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: guanylate cyclase soluble subunit alpha-2 [Trichechus manatus latirostris]
ENSG00000152404(CWF19L2)	--	2.932356762	195	3.400860758	224	3.086412735	223	2.594814359	194	2.361498074	168	2.766039873	205	0.966518582	-0.037949952	normal	0.779137302	-0.433075325	normal	0.960119904	-0.128799938	normal	0.585003091	-0.200229793	normal	--	--	--	--	--	[S]	Function unknown	Protein similar to CwfJ C-terminus 1;; Protein similar to CwfJ C-terminus 2	CWF19-like protein 2 GN=CWF19L2 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: CWF19-like protein 2 isoform X1 [Tupaia chinensis] 
ENSG00000152409(JMY)	--	2.613671701	412	3.229312434	511	3.063697412	480	3.475641736	549	3.239430789	511	4.89241639	774	0.773687275	0.382091598	normal	0.971079707	-0.021363335	normal	0.017517923	0.679306687	normal	0.307544477	0.366322132	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	--	--	--	--	--	Junction-mediating and -regulatory protein GN=JMY OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: junction-mediating and -regulatory protein [Ceratotherium simum simum]
ENSG00000152413(HOMER1)	--	4.380866067	417	5.080785511	429	4.797749688	409	3.78927989	342	4.549675696	394	3.034081194	284	0.879464506	-0.315596794	normal	0.958626804	-0.143679861	normal	0.360100143	-0.532126779	normal	0.17439731	-0.320771415	normal	--	--	--	K15010|0|umr:103681462|HOMER1; homer homolog 1 (Drosophila); K15010 homer (A)	FoxO signaling pathway (ko04068);; Glutamatergic synapse (ko04724)	--	--	WH1 domain	Homer protein homolog 1 GN=HOMER1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: homer protein homolog 1 [Loxodonta africana]
ENSG00000152422(XRCC4)	--	9.28739054	286	9.592484407	243	9.685627849	259	9.108302	274	10.15172873	290	7.96271952	245	0.963774183	-0.092165592	normal	0.93526437	0.232345005	normal	0.963962744	-0.087933804	normal	0.977448148	0.016484064	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: double-strand break repair (GO:0006302);; Biological Process: DNA recombination (GO:0006310);; 	K10886|0|hsa:7518|XRCC4; X-ray repair complementing defective repair in Chinese hamster cells 4; K10886 DNA-repair protein XRCC4 (A)	Non-homologous end-joining (ko03450)	--	--	DNA double-strand break repair and V(D)J recombination protein XRCC4	DNA repair protein XRCC4 GN=XRCC4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein XRCC4 isoform 1 [Orcinus orca]
ENSG00000152430(BOLL)	--	0.086463674	3	0	0	0	0	0	0	0.026168848	0	0.051990669	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Protein boule-like GN=BOLL OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein boule-like isoform X1 [Mustela putorius furo] 
ENSG00000152433(ZNF547)	--	21.88579958	506	22.429469	540	26.9332833	527	28.11696433	625	22.1025607	509	30.1295759	705	0.91366379	0.2731392	normal	0.966190247	-0.106413292	normal	0.692540351	0.410506932	normal	0.375580777	0.204490363	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:284306|ZNF547; zinc finger protein 547; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; XPA protein N-terminal"	Zinc finger protein 547 GN=ZNF547 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 548 [Mustela putorius furo] 
ENSG00000152439(ZNF773)	--	4.675775102	160	3.50576487	148	4.474885956	174	5.636636827	182	3.7778799	162	3.325944213	152	0.958437125	0.153650254	normal	0.962463157	0.107915883	normal	0.951304566	-0.201432778	normal	0.979218376	0.01979128	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:374928|ZNF773, ZNF419B; zinc finger protein 773; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2H2-type zinc-finger domain;; XPA protein N-terminal"	Zinc finger protein 773 GN=ZNF773 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 773 [Tupaia chinensis]
ENSG00000152443(ZNF776)	--	9.873920717	862	12.72045605	853	8.404111867	743	9.471477884	779	6.460782982	566	10.019353	764	0.961048225	-0.176565554	normal	0.070332235	-0.611828656	normal	0.97592255	0.031855044	normal	0.272197994	-0.242568855	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 776 GN=ZNF776 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 154-like [Equus przewalskii]
ENSG00000152454(ZNF256)	--	0.901199332	40	0.896774362	39	0.737916201	31	1.275311852	60	0.91223046	41	1.160943038	55	0.922099289	0.537185903	normal	0.98033636	0.048874791	normal	0.787384997	0.789591844	normal	0.42829059	0.481997059	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:10172|ZNF256, BMZF-3, BMZF3; zinc finger protein 256; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; XPA protein N-terminal"	Zinc finger protein 256 GN=ZNF256 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 256-like isoform X1 [Galeopterus variegatus]
ENSG00000152455(SUV39H2)	--	11.6475459	432	11.782748	496	12.92929981	503	14.464168	506	11.609516	461	12.1806464	455	0.948265243	0.196627166	normal	0.962680506	-0.126599427	normal	0.959277756	-0.152500996	normal	0.938411638	-0.030517888	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; 	"K11419|0|hsa:79723|SUV39H2, KMT1B; suppressor of variegation 3-9 homolog 2 (Drosophila) (EC:2.1.1.43); K11419 histone-lysine N-methyltransferase SUV39H [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[BK]	Chromatin structure and dynamics;; Transcription	SET domain;; Pre-SET motif;; Chromo (CHRromatin Organisation MOdifier) domain	Histone-lysine N-methyltransferase SUV39H2 GN=SUV39H2 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase SUV39H2 isoform 1 [Trichechus manatus latirostris]
ENSG00000152457(DCLRE1C)	--	4.116212075	309	3.999755817	285	5.734555311	354	5.3272771	378	4.843885557	326	4.21002505	312	0.922395306	0.25878222	normal	0.951754569	0.171631477	normal	0.948730032	-0.189631245	normal	0.831092618	0.078472135	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K10887|0|hsa:64421|DCLRE1C, A-SCID, DCLREC1C, RS-SCID, SCIDA, SNM1C; DNA cross-link repair 1C; K10887 DNA cross-link repair 1C protein [EC:3.1.-.-] (A)"	Non-homologous end-joining (ko03450);; Primary immunodeficiency (ko05340)	[L]	"Replication, recombination and repair"	DNA repair metallo-beta-lactamase;; Beta-lactamase superfamily domain;; Metallo-beta-lactamase superfamily	Protein artemis GN=DCLRE1C OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: protein artemis isoform 1 [Ceratotherium simum simum]
ENSG00000152463(OLAH)	--	0.115646352	3	0	0	0	0	0	0	0.037227801	0	0.139536099	2	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Biological Process: biosynthetic process (GO:0009058);; Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	"K01071|0|hsa:55301|OLAH, AURA1, SAST, THEDC1; oleoyl-ACP hydrolase (EC:3.1.2.14); K01071 medium-chain acyl-[acyl-carrier-protein] hydrolase [EC:3.1.2.21] (A)"	Fatty acid biosynthesis (ko00061)	--	--	Thioesterase domain;; Alpha/beta hydrolase family	"S-acyl fatty acid synthase thioesterase, medium chain GN=OLAH OS=Homo sapiens (Human) PE=2 SV=1"	I	Lipid transport and metabolism	"PREDICTED: S-acyl fatty acid synthase thioesterase, medium chain [Tupaia chinensis]"
ENSG00000152464(RPP38)	--	15.736599	358	12.97579806	303	15.10558	347	15.39043069	351	16.23287	385	14.08272213	331	0.96722864	-0.059064805	normal	0.875725645	0.322682396	normal	0.9659841	-0.076056465	normal	0.874611439	0.06089196	normal	--	--	--	K14523|2.04269e-159|hsa:10557|RPP38; ribonuclease P/MRP 38kDa subunit (EC:3.1.26.5); K14523 ribonucleases P/MRP protein subunit RPP38 [EC:3.1.26.5] (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	Ribonuclease P protein subunit p38 GN=RPP38 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribonuclease P protein subunit p38 [Galeopterus variegatus] 
ENSG00000152465(NMT2)	--	14.061814	749	12.222531	671	17.348165	871	11.948332	663	10.385201	561	8.463405	457	0.950201661	-0.20633886	normal	0.910995643	-0.279049681	normal	1.83E-05	-0.936485634	normal	0.04020673	-0.468566393	normal	[I]	Lipid transport and metabolism	Molecular Function: glycylpeptide N-tetradecanoyltransferase activity (GO:0004379);; 	K00671|0|hsa:9397|NMT2; N-myristoyltransferase 2 (EC:2.3.1.97); K00671 glycylpeptide N-tetradecanoyltransferase [EC:2.3.1.97] (A)	--	[I]	Lipid transport and metabolism	"Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain;; Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain"	Glycylpeptide N-tetradecanoyltransferase 2 GN=NMT2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: glycylpeptide N-tetradecanoyltransferase 2 isoform X1 [Elephantulus edwardii]
ENSG00000152475(ZNF837)	--	1.929977	64	2.79572	97	1.790281	64	1.587149	53	2.81402	94	2.358425	81	0.96381955	-0.295113164	normal	0.969044675	-0.065709811	normal	0.951154496	0.32472369	normal	1	-0.001259781	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 837 GN=ZNF837 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 837 [Odobenus rosmarus divergens]
ENSG00000152484(USP12)	--	16.25890952	1033	19.99732128	1309	18.35063213	1159	15.00163591	873	10.82520594	720	12.945053	855	0.922892872	-0.273176333	normal	5.47E-05	-0.88242675	normal	0.557230646	-0.446494669	normal	0.000902697	-0.537571351	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11842|0|ptr:735835|USP12, USP12P1; ubiquitin specific peptidase 12; K11842 ubiquitin carboxyl-terminal hydrolase 12/46 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 12 GN=USP12 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 12 [Orcinus orca]
ENSG00000152492(CCDC50)	--	8.698800966	985	8.348007913	943	10.38400539	1019	14.924875	1667	12.53129623	1500	10.52683169	1138	0.002714019	0.727344865	normal	0.025638099	0.647376195	normal	0.970519478	0.150843131	normal	0.022578037	0.524597794	normal	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 50  N-terminus	Coiled-coil domain-containing protein 50 GN=CCDC50 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 50 isoform X2 [Physeter catodon]
ENSG00000152495(CAMK4)	--	0.544561	51	0.383508722	41	0.748465149	55	0.101708322	11	0.09812191	9	0.073425517	14	0.000424045	-2.095680475	down	0.005166316	-2.035308035	down	0.001261889	-1.872929456	down	4.40E-05	-2.132367521	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05869|0|hsa:814|CAMK4, CaMK_IV, CaMK-GR, IV, caMK; calcium/calmodulin-dependent protein kinase IV (EC:2.7.11.17); K05869 calcium/calmodulin-dependent protein kinase IV [EC:2.7.11.17] (A)"	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Osteoclast differentiation (ko04380);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Oxytocin signaling pathway (ko04921);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Calcium/calmodulin-dependent protein kinase type IV GN=CAMK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type IV [Orcinus orca]
ENSG00000152503(TRIM36)	--	1.29479436	65	0.978629542	63	0.903188857	53	1.068683019	54	0.832253888	53	1.186708597	68	0.963777484	-0.29075962	normal	0.965218663	-0.263870728	normal	0.955770591	0.342600317	normal	0.940617376	-0.069473717	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K12013|0|mcf:101865566|uncharacterized LOC101865566; K12013 tripartite motif-containing protein 36 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"B-box zinc finger;; Fibronectin type III domain;; SPRY domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRIM36 GN=TRIM36 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM36 [Camelus ferus]
ENSG00000152518(ZFP36L2)	--	17.7217	913	19.7028	1015	15.775	822	11.9607	620	13.2651	690	12.9776	679	0.091383729	-0.587969905	normal	0.119366119	-0.577188052	normal	0.910192955	-0.28344358	normal	0.002865812	-0.488571181	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	K18753|5.99477e-162|ecb:100069189|ZFP36L2; ZFP36 ring finger protein-like 2; K18753 butyrate response factor 1 (A)	--	[R]	General function prediction only	"Tis11B like protein, N terminus;; Zinc finger C-x8-C-x5-C-x3-H type (and similar)"	"Zinc finger protein 36, C3H1 type-like 2 GN=ZFP36L2 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: ZFP36 ring finger protein-like 2 [Equus caballus]
ENSG00000152520(PAN3)	--	6.928963091	574	7.286144	577	6.938749454	570	5.500282947	466	7.167131914	599	6.49595081	553	0.857464012	-0.330568888	normal	0.97235873	0.03247459	normal	0.971861048	-0.051834253	normal	0.688756215	-0.10966295	normal	--	--	--	K12572|0|mcf:102142167|PAN3; PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae); K12572 PAB-dependent poly(A)-specific ribonuclease subunit 3 (A)	RNA degradation (ko03018)	[A]	RNA processing and modification	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	PAB-dependent poly(A)-specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181} OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: PAB-dependent poly(A)-specific ribonuclease subunit 3 [Leptonychotes weddellii]
ENSG00000152527(PLEKHH2)	--	3.071084989	468	3.347193286	495	2.658715297	386	1.383423861	202	1.975966244	297	1.704365248	259	3.82E-08	-1.23661531	down	0.008671783	-0.755378754	normal	0.225404976	-0.581141831	normal	4.46E-05	-0.852377724	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; 	--	--	[Z]	Cytoskeleton	PH domain;; MyTH4 domain;; FERM central domain;; Pleckstrin homology domain;; PH domain	Pleckstrin homology domain-containing family H member 2 GN=PLEKHH2 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: pleckstrin homology domain-containing family H member 2 [Ceratotherium simum simum]
ENSG00000152556(PFKM)	--	26.6039925	1642	25.65521705	1567	25.25559534	1464	24.52455495	1474	23.64243315	1358	28.5632253	1551	0.96990909	-0.18636569	normal	0.957316178	-0.227711952	normal	0.982339622	0.074916497	normal	0.60106109	-0.113657833	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: 6-phosphofructokinase activity (GO:0003872);; Biological Process: glycolytic process (GO:0006096);; 	"K00850|0|ptr:451863|PFKM; phosphofructokinase, muscle; K00850 6-phosphofructokinase 1 [EC:2.7.1.11] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; RNA degradation (ko03018);; AMPK signaling pathway (ko04152);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Phosphofructokinase	"ATP-dependent 6-phosphofructokinase, muscle type {ECO:0000255|HAMAP-Rule:MF_03184} GN=PFKM OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: 6-phosphofructokinase, muscle type isoform X2 [Tupaia chinensis] "
ENSG00000152558(TMEM123)	--	151.9507969	7685	156.325226	7488	166.9631863	7798	140.564178	7305	137.6942284	6808	135.887637	7053	0.994066552	-0.103971926	normal	0.991465956	-0.158742317	normal	0.992152047	-0.153127317	normal	0.528898375	-0.139330061	normal	--	--	--	--	--	--	--	--	Porimin (Precursor) GN=TMEM123 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: porimin [Tupaia chinensis]
ENSG00000152578(GRIA4)	--	0.021344149	2	0.074879218	4	0.01865376	0	0	0	0.023987782	0	0.018766983	1	--	--	--	--	--	--	--	--	--	--	--	--	[ET]	Amino acid transport and metabolism;; Signal transduction mechanisms	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05200|0|hsa:2893|GRIA4, GLUR4, GLUR4C, GLURD, GluA4; glutamate receptor, ionotropic, AMPA 4; K05200 glutamate receptor 4 (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Receptor family ligand binding region;; Ligated ion channel L-glutamate- and glycine-binding site;; Bacterial extracellular solute-binding proteins, family 3"	Glutamate receptor 4 (Precursor) GN=GRIA4 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: glutamate receptor 4 isoform X1 [Mustela putorius furo] 
ENSG00000152580(IGSF10)	--	0.438932257	98	0.48165	106	0.314421175	68	0.22450049	49	0.29138075	64	0.161018018	36	0.07018622	-1.008025866	normal	0.455757674	-0.735692679	normal	0.482894319	-0.897938885	normal	0.032041459	-0.890752789	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Leucine rich repeat;; CD80-like C2-set immunoglobulin domain;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Zona-pellucida-binding protein (Sp38)	Immunoglobulin superfamily member 10 (Precursor) GN=IGSF10 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 10 isoform X1 [Ursus maritimus]
ENSG00000152582(SPEF2)	--	1.39648878	112	0.911513786	68	1.508102086	110	1.694643232	114	1.057875222	81	1.59387508	119	0.969896295	-0.005226112	normal	0.962597479	0.226343816	normal	0.966810555	0.103794366	normal	0.884824168	0.093970123	normal	[F]	Nucleotide transport and metabolism	--	--	--	--	--	Domain of Unknown Function (DUF1042);; Adenylate kinase	Sperm flagellar protein 2 GN=SPEF2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sperm flagellar protein 2 isoform X3 [Oryctolagus cuniculus]
ENSG00000152583(SPARCL1)	--	0	0	0.032657962	2	0	0	0.193534082	1	0.015834819	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	Secreted protein acidic and rich in cysteine Ca binding region;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Follistatin/Osteonectin-like EGF domain	SPARC-like protein 1 (Precursor) GN=SPARCL1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: SPARC-like protein 1 [Equus przewalskii]
ENSG00000152601(MBNL1)	--	46.09449466	2917	54.22069878	3733	55.10453587	3404	53.0031463	3846	51.786213	3269	50.83643462	3474	0.873641228	0.367871912	normal	0.978181804	-0.212820476	normal	0.991103586	0.021066011	normal	0.835382416	0.053226058	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K14943|0|tup:102488526|MBNL1; muscleblind-like splicing regulator 1; K14943 muscleblind (A)	--	[K]	Transcription	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Muscleblind-like protein 1 GN=MBNL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: muscleblind-like protein 1 isoform 1 [Dasypus novemcinctus] 
ENSG00000152620(NADK2)	--	10.38967937	486	9.10729471	440	9.083379228	451	8.494746982	441	9.108207936	448	8.747438404	398	0.95507695	-0.170443945	normal	0.969849885	0.004553142	normal	0.950186693	-0.187978986	normal	0.687126832	-0.119000054	normal	--	--	Molecular Function: NAD+ kinase activity (GO:0003951);; Biological Process: NADP biosynthetic process (GO:0006741);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	ATP-NAD kinase	"NAD kinase 2, mitochondrial (Precursor) GN=NADK2 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: NAD kinase 2, mitochondrial isoform X2 [Canis lupus familiaris]"
ENSG00000152642(GPD1L)	--	7.3231728	499	6.572302231	440	8.1580786	549	10.98335807	668	10.47788193	694	6.1029684	422	0.750564645	0.388937878	normal	0.056750968	0.634255842	normal	0.764087586	-0.386636187	normal	0.556964795	0.239728615	normal	[C]	Energy production and conversion	"Molecular Function: glycerol-3-phosphate dehydrogenase [NAD+] activity (GO:0004367);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: glycerol-3-phosphate catabolic process (GO:0046168);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00006|0|pps:100983363|GPD1L; glycerol-3-phosphate dehydrogenase 1-like; K00006 glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] (A)	Glycerophospholipid metabolism (ko00564)	[C]	Energy production and conversion	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus;; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	Glycerol-3-phosphate dehydrogenase 1-like protein GN=GPD1L OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: glycerol-3-phosphate dehydrogenase 1-like protein [Orycteropus afer afer]
ENSG00000152661(GJA1)	--	86.0372	3967	90.6507	4200	81.2291	3697	118.468	5507	114.6202	5248	144.5958	6665	0.712931403	0.442240009	normal	0.957859992	0.299855075	normal	7.08E-05	0.84169831	normal	0.001489963	0.53331972	normal	--	--	--	"K07372|0|hsa:2697|GJA1, AVSD3, CMDR, CX43, GJAL, HLHS1, HSS, ODDD; gap junction protein, alpha 1, 43kDa; K07372 gap junction protein, alpha 1 (A)"	Gap junction (ko04540);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	--	--	Connexin;; Gap junction channel protein cysteine-rich domain;; Gap junction alpha-1 protein (Cx43)	Gap junction alpha-1 protein GN=GJA1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	gap junction alpha-1 protein [Oryctolagus cuniculus] 
ENSG00000152669(CCNO)	--	5.5868669	175	5.079258	172	4.7880592	169	5.5632714	189	5.8371394	211	5.655163	224	0.964898135	0.079527121	normal	0.926379363	0.271251476	normal	0.834079431	0.395103463	normal	0.479733385	0.253472058	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	"K10861|0|hsa:10309|CCNO, CCNU, CILD29, UDG2; cyclin O; K10861 uracil-DNA glycosylase 2 [EC:3.2.2.-] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	Cyclin-O GN=CCNO OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-O [Oryctolagus cuniculus]
ENSG00000152672(CLEC4F)	--	0	0	0	0	0	0	0	0	0	0	0.022402395	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10060|0|pps:100974761|CLEC4F; C-type lectin domain family 4, member F; K10060 C-type lectin domain family 4 member F (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; Golgin subfamily A member 5	C-type lectin domain family 4 member F GN=CLEC4F OS=Homo sapiens (Human) PE=2 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: LOW QUALITY PROTEIN: C-type lectin domain family 4 member F [Physeter catodon]
ENSG00000152683(SLC30A6)	--	19.21934038	1229	18.41076195	1192	19.7830253	1274	18.244478	1114	15.80180746	1058	16.75817569	1070	0.967887218	-0.172341518	normal	0.962249751	-0.193210792	normal	0.937133027	-0.259709078	normal	0.261956251	-0.209916342	normal	--	--	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14693|0|hsa:55676|SLC30A6, MST103, MSTP103, ZNT6; solute carrier family 30 (zinc transporter), member 6; K14693 solute carrier family 30 (zinc transporter), member 6 (A)"	--	[P]	Inorganic ion transport and metabolism	Cation efflux family	Zinc transporter 6 GN=SLC30A6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	hypothetical protein PANDA_019256 [Ailuropoda melanoleuca]
ENSG00000152684(PELO)	--	11.36112	894	14.373784	1041	13.782868	1011	12.875343	929	13.771736	1006	12.73607	903	0.978236778	0.024530146	normal	0.977473835	-0.070661891	normal	0.964917693	-0.171005728	normal	0.770759472	-0.075056182	normal	[R]	General function prediction only	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	eRF1 domain 1;; eRF1 domain 2;; eRF1 domain 3	Protein pelota homolog GN=PELO OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	protein pelota homolog [Bos taurus] 
ENSG00000152689(RASGRP3)	--	0.157225631	13	0.186952904	8	0.130095813	10	1.852295903	81	2.41650743	198	1.293098907	83	3.74E-08	2.476438955	up	0	4.370899934	up	3.19E-10	2.868313905	up	0.002750843	3.52500897	up	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12362|0|hsa:25780|RASGRP3, GRP3; RAS guanyl releasing protein 3 (calcium and DAG-regulated); K12362 RAS guanyl-releasing protein 3 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; B cell receptor signaling pathway (ko04662);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	RasGEF domain;; EF-hand domain pair;; Phorbol esters/diacylglycerol binding domain (C1 domain);; EF hand;; RasGEF N-terminal motif;; EF-hand domain;; EF hand	Ras guanyl-releasing protein 3 GN=RASGRP3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: ras guanyl-releasing protein 3 isoform X1 [Myotis lucifugus]
ENSG00000152700(SAR1B)	--	18.20810439	971	19.82051871	922	23.10646089	937	19.898441	933	18.7417163	968	21.86550996	1002	0.975849619	-0.08828395	normal	0.977505303	0.048735722	normal	0.976154777	0.088332229	normal	0.965782714	0.015768946	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07953|8.37234e-145|hsa:51128|SAR1B, ANDD, CMRD, GTBPB, SARA2; secretion associated, Ras related GTPase 1B; K07953 GTP-binding protein SAR1 [EC:3.6.5.-] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Legionellosis (ko05134)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Miro-like protein;; Ras family;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	GTP-binding protein SAR1b GN=SAR1B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	GTP-binding protein SAR1b [Sus scrofa] 
ENSG00000152749(GPR180)	--	4.026705	488	4.03105887	484	3.584412566	423	3.890024777	477	3.673198	444	3.447040668	419	0.969556058	-0.063521847	normal	0.959434164	-0.145399408	normal	0.970018037	-0.02192012	normal	0.804842596	-0.079858603	normal	--	--	Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: response to pheromone (GO:0019236);; 	--	--	[S]	Function unknown	Rhodopsin-like GPCR transmembrane domain;; Lung seven transmembrane receptor	Integral membrane protein GPR180 (Precursor) GN=GPR180 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: integral membrane protein GPR180 [Ceratotherium simum simum]
ENSG00000152763(WDR78)	--	0.731683743	31	0.67674636	30	0.74597254	26	0.571298282	24	0.280795318	19	0.597497765	24	0.978613548	-0.378675388	normal	0.958845871	-0.639548754	normal	0.986173767	-0.116701652	normal	0.625892863	-0.398420739	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 78 GN=WDR78 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: WD repeat-containing protein 78 [Mustela putorius furo] 
ENSG00000152766(ANKRD22)	--	2.35831123	88	0.507129766	25	1.426972	62	2.022124951	87	2.033987	83	1.250871288	54	0.972002994	-0.046503788	normal	0.00023556	1.651876211	up	0.971424948	-0.202308376	normal	0.702729371	0.334087037	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 22 GN=ANKRD22 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 22 [Vicugna pacos]
ENSG00000152767(FARP1)	--	8.727171405	799	7.823178	767	7.208329	712	8.877753	747	10.112448	853	9.65693743	726	0.969003564	-0.127665553	normal	0.968647827	0.131646393	normal	0.975636193	0.019759303	normal	0.984787135	0.008732324	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K17477|0|ptr:452632|FARP1; FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived); K17477 FERM, RhoGEF and pleckstrin domain-containing protein 1 (A)"	--	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; FERM C-terminal PH-like domain;; FERM N-terminal domain;; FERM adjacent (FA);; FERM central domain	"FERM, RhoGEF and pleckstrin domain-containing protein 1 GN=FARP1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: FERM, RhoGEF and pleckstrin domain-containing protein 1 isoform X1 [Orycteropus afer afer]"
ENSG00000152778(IFIT5)	--	8.53343	518	7.54104	454	8.74679	520	7.87489	483	8.49619	516	7.84569	479	0.963118591	-0.131357556	normal	0.956577003	0.162743461	normal	0.963955505	-0.126394294	normal	0.923778512	-0.034625922	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Interferon-induced protein with tetratricopeptide repeats 5 GN=IFIT5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: interferon-induced protein with tetratricopeptide repeats 5 [Pteropus alecto] 
ENSG00000152779(SLC16A12)	--	0.04271154	3	0.028398762	2	0.09950335	6	0.16989794	12	0.06912821	4	0.19836283	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K11810|0|hsa:387700|SLC16A12, CJMG, MCT12; solute carrier family 16, member 12; K11810 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 12 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 12 GN=SLC16A12 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: monocarboxylate transporter 12 [Ceratotherium simum simum]
ENSG00000152782(PANK1)	--	4.367809	202	5.987567	278	5.270412404	227	5.006177	238	5.810462	257	6.371162862	300	0.946729753	0.204340984	normal	0.958033942	-0.133984773	normal	0.805042744	0.39170184	normal	0.678187501	0.148585855	normal	[H]	Coenzyme transport and metabolism	Molecular Function: pantothenate kinase activity (GO:0004594);; Molecular Function: ATP binding (GO:0005524);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; 	K09680|0|mcf:102115196|PANK1; pantothenate kinase 1; K09680 type II pantothenate kinase [EC:2.7.1.33] (A)	Pantothenate and CoA biosynthesis (ko00770)	[H]	Coenzyme transport and metabolism	Fumble	Pantothenate kinase 1 GN=PANK1 OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: pantothenate kinase 1 isoform X1 [Mustela putorius furo]
ENSG00000152784(PRDM8)	--	1.043205489	62	0.748816576	40	0.594085671	34	0.416920865	21	0.427156306	24	0.530413159	28	0.008120759	-1.52473179	down	0.910423659	-0.722747443	normal	0.980032271	-0.274905001	normal	0.100683277	-0.918523488	normal	--	--	--	--	--	[K]	Transcription	"Zinc finger, C2H2 type"	PR domain zinc finger protein 8 GN=PRDM8 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: PR domain zinc finger protein 8 [Ochotona princeps]
ENSG00000152795(HNRNPDL)	--	99.783053	3273	95.826085	3003	105.0270047	3271	119.745963	3937	132.0983508	4249	93.78511273	3060	0.973801235	0.235549919	normal	0.541183276	0.479088554	normal	0.988289907	-0.104441614	normal	0.347621152	0.214585293	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13044|0|pps:100973515|HNRNPDL, HNRPDL; heterogeneous nuclear ribonucleoprotein D-like; K13044 heterogeneous nuclear ribonucleoprotein A/B/D (A)"	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Heterogeneous nuclear ribonucleoprotein D-like GN=HNRNPDL OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein D-like isoform 1 [Dasypus novemcinctus] 
ENSG00000152804(HHEX)	--	9.440640259	238	10.959069	267	10.19482509	260	11.18253012	299	15.90887554	402	14.96373018	392	0.904376567	0.296640164	normal	0.272088229	0.566298423	normal	0.223042778	0.581278412	normal	0.032110725	0.494462829	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K08024|4.49016e-137|ptr:450612|HHEX; hematopoietically expressed homeobox; K08024 homeobox protein HEX (A)	Maturity onset diabetes of the young (ko04950);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Homeobox domain	Hematopoietically-expressed homeobox protein HHEX GN=HHEX OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	hematopoietically-expressed homeobox protein HHEX [Sus scrofa]
ENSG00000152818(UTRN)	--	9.936370039	1841	12.13447281	1817	19.62101768	1898	8.818350951	1355	9.357876391	1294	8.737893206	1383	0.458079968	-0.472567286	normal	0.316708209	-0.510641117	normal	0.498042116	-0.4645348	normal	0.001020856	-0.483630249	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[NTZ]	Cell motility;; Signal transduction mechanisms;; Cytoskeleton	"Spectrin repeat;; EF hand;; EF-hand;; Calponin homology (CH) domain;; Zinc finger, ZZ type;; WW domain;; CAMSAP CH domain"	Utrophin GN=UTRN OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: utrophin isoform X6 [Balaenoptera acutorostrata scammoni]
ENSG00000152822(GRM1)	--	0.016147362	2	0.026368584	2	0.012971282	0	0.013246616	1	0.01567753	1	0.079204702	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04603|0|hsa:2911|GRM1, GPRC1A, MGLU1, MGLUR1, PPP1R85, SCAR13; glutamate receptor, metabotropic 1; K04603 metabotropic glutamate receptor 1 (A)"	Calcium signaling pathway (ko04020);; FoxO signaling pathway (ko04068);; Neuroactive ligand-receptor interaction (ko04080);; Gap junction (ko04540);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Long-term depression (ko04730);; Estrogen signaling pathway (ko04915)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Homer-binding domain of metabotropic glutamate receptor;; Nine Cysteines Domain of family 3 GPCR	Metabotropic glutamate receptor 1 (Precursor) GN=GRM1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: metabotropic glutamate receptor 1 isoform X1 [Tupaia chinensis] 
ENSG00000152894(PTPRK)	--	10.79879108	1073	10.68018231	1109	10.26717776	1000	22.94068861	2444	21.711202	2216	20.84764663	2248	6.73E-10	1.155635988	up	1.40E-06	0.976312078	normal	6.59E-10	1.15914973	up	2.22E-16	1.096700814	up	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; Cellular Component: membrane (GO:0016020);; 	"K06776|0|cfr:102518793|PTPRK; protein tyrosine phosphatase, receptor type, K; K06776 receptor-type tyrosine-protein phosphatase kappa [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; MAM domain;; Fibronectin type III domain;; Dual specificity phosphatase, catalytic domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Tyrosine phosphatase family"	Receptor-type tyrosine-protein phosphatase kappa (Precursor) GN=PTPRK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase kappa isoform X1 [Vicugna pacos]
ENSG00000152904(GGPS1)	--	18.09386	550	21.16835	593	13.603618	440	16.55908081	520	15.22354	498	16.481312	560	0.966476394	-0.111432047	normal	0.914224911	-0.272553332	normal	0.84800608	0.338597927	normal	0.948073478	-0.026019032	normal	[H]	Coenzyme transport and metabolism	Biological Process: isoprenoid biosynthetic process (GO:0008299);; 	"K00804|0|ptr:100610192|GGPS1; geranylgeranyl diphosphate synthase 1; K00804 geranylgeranyl diphosphate synthase, type III [EC:2.5.1.1 2.5.1.10 2.5.1.29] (A)"	Terpenoid backbone biosynthesis (ko00900)	[H]	Coenzyme transport and metabolism	Polyprenyl synthetase	Geranylgeranyl pyrophosphate synthase GN=GGPS1 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: geranylgeranyl pyrophosphate synthase isoform X1 [Oryctolagus cuniculus]
ENSG00000152910(CNTNAP4)	--	0.014051505	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; F5/8 type C domain;; Concanavalin A-like lectin/glucanases superfamily	Contactin-associated protein-like 4 (Precursor) GN=CNTNAP4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: contactin-associated protein-like 4 [Ailuropoda melanoleuca]
ENSG00000152926(ZNF117)	--	2.96867959	168	4.123302291	182	3.124660614	137	4.085461622	249	4.993194956	295	4.057322359	276	0.525247414	0.532826936	normal	0.116367338	0.670931586	normal	0.000476756	0.994314095	normal	0.003246206	0.730441569	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; C1-like domain"	Zinc finger protein 117 GN=ZNF117 OS=Homo sapiens (Human) PE=2 SV=5	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 708-like [Ursus maritimus]
ENSG00000152936(LMNTD1)	--	0.045520133	1	0	0	0	0	0.322231496	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[DY]	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	Lamin Tail Domain	Lamin tail domain-containing protein 1 GN=LMNTD1 OS=Homo sapiens (Human) PE=2 SV=2	DY	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	PREDICTED: intermediate filament tail domain-containing protein 1 [Lipotes vexillifer]
ENSG00000152939(MARVELD2)	--	1.278616939	93	1.576495358	103	1.946420684	121	1.986190266	141	1.605570331	116	1.610989698	119	0.685915306	0.561972616	normal	0.962812047	0.148005375	normal	0.968990318	-0.031934445	normal	0.637294429	0.224842916	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K17291|0|hsa:153562|MARVELD2, DFNB49, MARVD2, MRVLDC2, Tric; MARVEL domain containing 2; K17291 MARVEL domain-containing protein 2 (A)"	--	--	--	Occludin homology domain;; Membrane-associating domain	MARVEL domain-containing protein 2 GN=MARVELD2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: MARVEL domain-containing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000152942(RAD17)	--	10.95873498	553	10.916415	500	10.74430218	545	9.248423649	482	8.437541884	440	10.0190669	494	0.937671165	-0.228398201	normal	0.945109613	-0.205189016	normal	0.960653568	-0.149600417	normal	0.42098713	-0.195520602	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	K06662|0|pon:100190842|RAD17; RAD17 homolog (S. pombe); K06662 cell cycle checkpoint protein (A)	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Rad17 cell cycle checkpoint protein;; AAA domain;; ATPase family associated with various cellular activities (AAA);; Holliday junction DNA helicase ruvB N-terminus	Cell cycle checkpoint protein RAD17 GN=RAD17 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: cell cycle checkpoint protein RAD17 [Vicugna pacos]
ENSG00000152944(MED21)	--	20.97382215	856	19.98447183	858	25.8732817	980	24.890537	1087	25.28675132	1026	23.28187307	986	0.886975431	0.313336923	normal	0.944032397	0.236173535	normal	0.979420128	0.000513665	normal	0.372489554	0.180809173	normal	--	--	--	"K15152|8.64336e-93|ptr:465356|MED21, SURB7; mediator complex subunit 21; K15152 mediator of RNA polymerase II transcription subunit 21 (A)"	--	[K]	Transcription	Subunit 21 of Mediator complex	Mediator of RNA polymerase II transcription subunit 21 GN=MED21 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 21 [Dasypus novemcinctus]
ENSG00000152952(PLOD2)	--	179.6144459	11358	165.595727	10388	182.503967	11164	268.9418274	17100	157.4285499	9944	176.3225926	11059	0.317141445	0.559393188	normal	0.995553404	-0.084433711	normal	0.996521276	-0.021921551	normal	0.70229351	0.188643765	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13645|0|nle:100605215|PLOD2; procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; K13645 procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 [EC:1.14.11.4] (A)"	Lysine degradation (ko00310)	[O]	"Posttranslational modification, protein turnover, chaperones"	2OG-Fe(II) oxygenase superfamily	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (Precursor) GN=PLOD2 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 isoform X1 [Leptonychotes weddellii]"
ENSG00000152953(STK32B)	--	8.828051462	603	8.337273413	574	11.02969932	756	4.9721309	325	4.005301945	268	6.133118183	421	8.53E-05	-0.919305773	normal	6.12E-07	-1.115833969	down	0.000291199	-0.850544317	normal	0.000105635	-0.95078075	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08793|0|hsa:55351|STK32B, HSA250839, STK32, STKG6, YANK2; serine/threonine kinase 32B (EC:2.7.11.1); K08793 serine/threonine kinase 32 [EC:2.7.11.1] (A)"	--	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase 32B GN=UNQ3003/PRO9744 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 32B [Orcinus orca]
ENSG00000152954(NRSN1)	--	0	0	0	0	0	0	0	0	0.049077092	1	0.073978866	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Neurensin	Neurensin-1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: neurensin-1 [Equus caballus]
ENSG00000152977(ZIC1)	--	0.0402942	2	0.0126336	1	0	0	0.059761682	3	0.3442803	6	0.13248084	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09224|0|ggo:101126140|ZIC1; zinc finger protein ZIC 1; K09224 zinc finger protein ZIC 1 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein ZIC 1 GN=ZIC1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein ZIC 1 [Tupaia chinensis] 
ENSG00000152990(ADGRA3)	--	15.53327271	1283	13.88470333	1145	13.76202421	1132	12.623815	1051	13.240265	1088	12.261637	1021	0.887277969	-0.318168947	normal	0.976970521	-0.094966906	normal	0.969481876	-0.15696163	normal	0.318798778	-0.19329896	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: protein binding (GO:0005515);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08462|0|hsa:166647|GPR125, PGR21, TEM5L, ADGRA3; G protein-coupled receptor 125; K08462 G protein-coupled receptor 125 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; 7 transmembrane receptor (Secretin family);; Leucine Rich repeats (2 copies);; Latrophilin/CL-1-like GPS domain;; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Hormone receptor domain	Probable G-protein coupled receptor 125 (Precursor) GN=GPR125 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 125 [Equus przewalskii]
ENSG00000153006(SREK1IP1)	--	5.23788	513	5.0388	491	4.83906	462	6.34649	630	6.05318	594	6.00871	592	0.919363075	0.264843981	normal	0.926333621	0.2526051	normal	0.832824026	0.34840296	normal	0.17097777	0.287351693	normal	--	--	--	--	--	[S]	Function unknown	Zinc knuckle	Protein SREK1IP1 GN=SREK1IP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein SREK1IP1 [Galeopterus variegatus]
ENSG00000153012(LGI2)	--	0.359323674	6	0.0258399	3	0.114552178	2	0.034693828	4	0.0337482	3	0.0172699	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	EPTP domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat	Leucine-rich repeat LGI family member 2 (Precursor) GN=LGI2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat LGI family member 2 [Orycteropus afer afer]
ENSG00000153015(CWC27)	--	10.792652	493	10.0894514	468	10.99012714	503	13.518798	618	12.5682144	578	10.51381317	485	0.896685307	0.294366151	normal	0.90697343	0.282312241	normal	0.970067928	-0.060679293	normal	0.472204644	0.177610981	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	K12737|0|nle:100597891|CWC27; CWC27 spliceosome-associated protein homolog (S. cerevisiae); K12737 peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase CWC27 homolog GN=CWC27 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase CWC27 homolog [Trichechus manatus latirostris]
ENSG00000153029(MR1)	--	6.966671412	463	5.353006136	375	5.904977979	388	10.64435215	704	13.53185357	855	10.40918958	722	0.145566117	0.57218108	normal	2.24E-08	1.164412378	up	0.000134021	0.885081996	normal	1.03E-07	0.874597621	normal	--	--	--	--	--	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain"	Major histocompatibility complex class I-related gene protein (Precursor) GN=MR1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: major histocompatibility complex class I-related gene protein-like isoform 1 [Ceratotherium simum simum]
ENSG00000153037(SRP19)	--	26.42977812	532	24.80735168	547	24.70064556	467	25.00173831	499	27.679083	541	27.12729371	514	0.96463611	-0.122852247	normal	0.971346062	-0.037235283	normal	0.963299199	0.129654031	normal	0.975756335	-0.01387462	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: SRP-dependent cotranslational protein targeting to membrane (GO:0006614);; Molecular Function: 7S RNA binding (GO:0008312);; Cellular Component: signal recognition particle (GO:0048500);; 	K03105|1.39517e-96|pon:100172362|SRP19; signal recognition particle 19kDa (EC:3.6.5.4); K03105 signal recognition particle subunit SRP19 (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SRP19 protein	Signal recognition particle 19 kDa protein GN=SRP19 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle 19 kDa protein [Felis catus] 
ENSG00000153044(CENPH)	--	25.84989	560	20.598109	436	22.21890476	483	18.93985046	420	18.3864705	399	18.61890901	407	0.601038905	-0.444456157	normal	0.957857458	-0.148826106	normal	0.924343029	-0.254416935	normal	0.194954257	-0.291964164	normal	--	--	Cellular Component: kinetochore (GO:0000776);; Biological Process: kinetochore assembly (GO:0051382);; 	K11500|2.25661e-158|hsa:64946|CENPH; centromere protein H; K11500 centromere protein H (A)	--	--	--	Centromere protein H (CENP-H)	Centromere protein H OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein H [Equus caballus]
ENSG00000153046(CDYL)	--	10.44383029	685	10.64155414	709	10.04741961	665	14.00109716	919	15.39188475	1019	11.19121638	732	0.737492091	0.392366481	normal	0.357747175	0.500974167	normal	0.967447843	0.129916173	normal	0.084373938	0.353086672	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	--	--	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family;; Chromo (CHRromatin Organisation MOdifier) domain	Chromodomain Y-like protein GN=CDYL OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_013583 [Ailuropoda melanoleuca]
ENSG00000153048(CARHSP1)	--	88.27343706	1673	90.12098586	1568	81.68699812	1577	79.65952088	1748	82.9034945	1704	66.637078	1370	0.985078679	0.032406361	normal	0.981498908	0.098482089	normal	0.962777856	-0.211080842	normal	0.950458395	-0.020695896	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[J]	"Translation, ribosomal structure and biogenesis"	'Cold-shock' DNA-binding domain	Calcium-regulated heat stable protein 1 GN=CARHSP1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: calcium-regulated heat stable protein 1 [Ceratotherium simum simum]
ENSG00000153060(TEKT5)	--	0	0	0.241066189	3	0.0303998	0	0.0311885	1	0.030641	0	0.0739453	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18632|0|hsa:146279|TEKT5, CT149; tektin 5; K18632 tektin-5 (A)"	--	[Z]	Cytoskeleton	Tektin family	Tektin-5 GN=TEKT5 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: tektin-5 [Loxodonta africana]
ENSG00000153064(BANK1)	--	0.422572121	29	0.889040093	50	0.598555804	41	1.355550351	92	1.74249881	117	1.875998298	127	0.00019019	1.585192171	up	0.004283426	1.181072782	up	5.85E-06	1.587859313	up	7.48E-05	1.465187021	up	--	--	--	--	--	--	--	"Dof, BCAP, and BANK (DBB) motif,"	B-cell scaffold protein with ankyrin repeats GN=BANK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: B-cell scaffold protein with ankyrin repeats [Orcinus orca]
ENSG00000153066(TXNDC11)	--	14.32061809	823	13.86533994	801	13.01268622	754	13.13953918	755	11.35438331	650	14.58472957	843	0.964964061	-0.154945903	normal	0.872431364	-0.322112595	normal	0.965730524	0.152387475	normal	0.685891421	-0.102156518	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain	Thioredoxin domain-containing protein 11 GN=TXNDC11 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin domain-containing protein 11 [Trichechus manatus latirostris]
ENSG00000153071(DAB2)	--	7.388263445	558	8.684114306	668	8.69606374	676	8.824598207	690	9.165587259	723	16.69920727	1297	0.913519522	0.274817484	normal	0.970966197	0.092519626	normal	9.11E-06	0.930263288	normal	0.420950848	0.491635349	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12475|0|pps:100973481|DAB2; Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila); K12475 disabled homolog 2 (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID)	Disabled homolog 2 GN=DAB2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: disabled homolog 2 isoform X4 [Mustela putorius furo] 
ENSG00000153093(ACOXL)	--	0.02340726	1	0	0	0	0	0	0	0	0	0.023261407	1	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	"Molecular Function: acyl-CoA oxidase activity (GO:0003997);; Cellular Component: peroxisome (GO:0005777);; Biological Process: fatty acid beta-oxidation (GO:0006635);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	"Acyl-CoA oxidase;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	Acyl-coenzyme A oxidase-like protein GN=ACOXL OS=Homo sapiens (Human) PE=2 SV=3	I	Lipid transport and metabolism	PREDICTED: acyl-coenzyme A oxidase-like protein [Ursus maritimus]
ENSG00000153094(BCL2L11)	--	5.745106543	455	5.351511622	391	4.219612299	332	3.303195991	226	3.856980799	295	3.953315701	320	1.28E-05	-1.035308569	down	0.707497548	-0.425976566	normal	0.966693893	-0.061119183	normal	0.051586989	-0.506663653	normal	--	--	--	K16341|5.81967e-120|pps:100973549|BCL2L11; BCL2-like 11 (apoptosis facilitator); K16341 Bcl-2-like protein 11 (A)	FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; MicroRNAs in cancer (ko05206)	--	--	"Bcl-x interacting, BH3 domain;; Bim protein N-terminus"	Bcl-2-like protein 11 GN=BCL2L11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bcl-2-like protein 11-like isoform X3 [Tupaia chinensis]
ENSG00000153107(ANAPC1)	--	21.7462363	2932	23.27308241	3160	23.73890258	3169	15.87000142	2201	15.39191154	2080	14.37052819	1942	0.626558863	-0.444288454	normal	0.042417644	-0.624396401	normal	0.003299516	-0.714335978	normal	2.52E-05	-0.595066023	normal	--	--	Cellular Component: anaphase-promoting complex (GO:0005680);; 	"K03348|0|hsa:64682|ANAPC1, APC1, MCPR, TSG24; anaphase promoting complex subunit 1; K03348 anaphase-promoting complex subunit 1 (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	Anaphase-promoting complex subunit 1;; Proteasome/cyclosome repeat	Anaphase-promoting complex subunit 1 GN=ANAPC1 OS=Homo sapiens (Human) PE=1 SV=1	DO	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: anaphase-promoting complex subunit 1 [Ailuropoda melanoleuca] 
ENSG00000153113(CAST)	--	87.59329242	5859	92.51478363	6169	93.91400142	5961	92.47441977	6657	93.59255266	6605	87.29469428	6031	0.991033887	0.153347712	normal	0.993681312	0.077077095	normal	0.99428988	0.008549263	normal	0.748052226	0.079474012	normal	--	--	--	K04281|0|mcf:101866970|uncharacterized LOC101866970; K04281 calpastatin (A)	--	--	--	Calpain inhibitor	Calpastatin GN=CAST OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: calpastatin isoform X1 [Galeopterus variegatus]
ENSG00000153130(SCOC)	--	45.58218152	1058	46.29969353	1075	51.18494467	1134	44.41614772	1039	39.89529055	899	42.5010061	981	0.978896323	-0.056892861	normal	0.920821924	-0.278940436	normal	0.95405871	-0.217075502	normal	0.357030962	-0.183808095	normal	--	--	--	--	--	[R]	General function prediction only	Predicted coiled-coil protein (DUF2205)	Short coiled-coil protein GN=SCOC OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: short coiled-coil protein isoform X1 [Capra hircus]
ENSG00000153132(CLGN)	--	9.306244248	587	8.652946604	547	9.617079237	589	10.330338	646	10.89808425	675	11.92137	746	0.968588166	0.107074189	normal	0.909290682	0.281219125	normal	0.856520793	0.331857776	normal	0.249698436	0.24194253	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: protein folding (GO:0006457);; Molecular Function: unfolded protein binding (GO:0051082);; 	K09551|0|hsa:1047|CLGN; calmegin; K09551 calmegin (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Calreticulin family	Calmegin (Precursor) GN=CLGN OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	Calmegin [Pteropus alecto]
ENSG00000153140(CETN3)	--	15.51769777	366	14.29427972	325	18.271364	362	13.09316698	312	11.43835046	261	12.0437975	259	0.921830588	-0.259946418	normal	0.868065365	-0.336067552	normal	0.537679658	-0.488902837	normal	0.146306432	-0.361553957	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K16466|3.78555e-132|hsa:1070|CETN3, CDC31, CEN3; centrin, EF-hand protein, 3; K16466 centrin-3 (A)"	--	[ZD]	"Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning"	EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand	Centrin-3 GN=CETN3 OS=Homo sapiens (Human) PE=1 SV=2	DTZ	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms;; Cytoskeleton"	PREDICTED: centrin-3 isoform X2 [Canis lupus familiaris] 
ENSG00000153147(SMARCA5)	--	15.43439188	2151	15.75146588	2184	15.06560454	2057	18.98163147	2661	19.24966028	2681	16.27909955	2271	0.948811494	0.27595124	normal	0.950950603	0.274200185	normal	0.982292079	0.134400397	normal	0.184806308	0.230489558	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Biological Process: chromatin remodeling (GO:0006338);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; Molecular Function: nucleosome binding (GO:0031491);; Biological Process: ATP-dependent chromatin remodeling (GO:0043044);; "	"K11654|0|hsa:8467|SMARCA5, ISWI, SNF2H, WCRF135, hISWI, hSNF2H; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5; K11654 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [EC:3.6.4.-] (A)"	--	[K]	Transcription	"SNF2 family N-terminal domain;; SLIDE;; HAND;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase;; Class II histone deacetylase complex subunits 2 and 3;; DNA-binding domain"	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 GN=SMARCA5 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 [Odobenus rosmarus divergens]
ENSG00000153157(SYCP2L)	--	1.738528016	108	1.8853413	114	1.748236018	105	1.618146852	100	1.08656382	67	1.520708257	94	0.965820212	-0.139796031	normal	0.318402965	-0.774661484	normal	0.964187681	-0.16542856	normal	0.451417836	-0.346917855	normal	--	--	--	--	--	--	--	--	Synaptonemal complex protein 2-like GN=SYCP2L OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: synaptonemal complex protein 2-like [Panthera tigris altaica]
ENSG00000153162(BMP6)	--	0.93617	47	1.0523	54	0.613958	31	1.16835	59	1.88364	95	1.7281	88	0.967529205	0.288782332	normal	0.457684552	0.776938638	normal	0.001191051	1.453072086	up	0.053978952	0.853688872	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K16620|0|hsa:654|BMP6, VGR, VGR1; bone morphogenetic protein 6; K16620 bone morphogenetic protein 6 (A)"	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Ovarian steroidogenesis (ko04913)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Bone morphogenetic protein 6 (Precursor) GN=BMP6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: bone morphogenetic protein 6, partial [Eptesicus fuscus]"
ENSG00000153165(RGPD3)	--	0.074245375	8	0.138757961	15	0.157390423	16	0.055231419	6	0.054020273	5	0.082917767	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:653489|RGPD3, RGP3; RANBP2-like and GRIP domain containing 3; K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; GRIP domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RanBP2-like and GRIP domain-containing protein 3 GN=RGPD3 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ceratotherium simum simum]
ENSG00000153179(RASSF3)	--	20.31864469	1100	21.11774816	1144	19.34920824	1019	24.54260075	1326	19.37941501	1035	24.723502	1293	0.948444299	0.238441313	normal	0.967724166	-0.165652498	normal	0.865548794	0.33483465	normal	0.503145036	0.141720161	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	K09852|1.94683e-146|ptr:743444|RASSF3; Ras association (RalGDS/AF-6) domain family member 3; K09852 Ras association domain-containing protein 3 (A)	--	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain	Ras association domain-containing protein 3 GN=RASSF3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	Ras association domain-containing protein 3 [Pteropus alecto]
ENSG00000153187(HNRNPU)	--	186.0981176	13717	171.4004641	12906	186.8089609	14006	210.8680089	15564	204.7857618	15201	179.3444068	13231	0.995584157	0.151399706	normal	0.992393636	0.214674547	normal	0.996540374	-0.090404285	normal	0.721371218	0.093323399	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12888|0|ptr:457867|HNRNPU, HNRPU; heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); K12888 heterogeneous nuclear ribonucleoprotein U (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	AAA domain;; SPRY domain;; SAP domain;; Zeta toxin	Heterogeneous nuclear ribonucleoprotein U GN=HNRNPU OS=Homo sapiens (Human) PE=1 SV=6	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein U isoform X1 [Bubalus bubalis]
ENSG00000153201(RANBP2)	--	19.0038288	4354	20.2113742	4604	21.35985515	4779	15.63307821	3589	14.99434208	3422	13.48841417	3079	0.945527532	-0.309471238	normal	0.683543802	-0.449302758	normal	0.025467019	-0.642283033	normal	0.001862597	-0.466669945	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein folding (GO:0006457);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:5903|RANBP2, ADANE, ANE1, IIAE3, NUP358, TRP1, TRP2; RAN binding protein 2 (EC:5.2.1.8); K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; Zn-finger in Ran binding protein and others;; Nup358/RanBP2 E3 ligase domain;; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD;; WH1 domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat	E3 SUMO-protein ligase RanBP2 GN=RANBP2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ailuropoda melanoleuca]
ENSG00000153207(AHCTF1)	--	23.14399934	3379	21.68684891	3366	25.34382265	3615	19.00677805	3157	19.6394511	3256	20.719852	2681	0.987188558	-0.128813739	normal	0.98973348	-0.069329362	normal	0.671862116	-0.439301645	normal	0.246886862	-0.209519728	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	Nuclear pore complex assembly	Protein ELYS GN=AHCTF1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: protein ELYS [Ceratotherium simum simum]
ENSG00000153208(MERTK)	--	2.223395251	158	2.333666	121	2.040957	126	0.7424492	46	0.7500166	51	0.36970447	25	1.15E-08	-1.776964985	down	0.001325975	-1.243185283	down	1.13E-10	-2.273908989	down	3.03E-07	-1.753735586	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05117|0|hsa:10461|MERTK, MER, RP38, Tyro12, c-Eyk, c-mer; MER proto-oncogene, tyrosine kinase (EC:2.7.10.1); K05117 c-mer proto-oncogene tyrosine kinase [EC:2.7.10.1] (A)"	--	--	--	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Tyrosine-protein kinase Mer (Precursor) GN=MERTK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase Mer [Tupaia chinensis]
ENSG00000153214(TMEM87B)	--	14.87328	1069	12.33674406	818	13.667173	927	11.62633	843	10.5938527	729	9.3200993	666	0.78801816	-0.372884404	normal	0.957158202	-0.187241651	normal	0.407539025	-0.484401905	normal	0.080928635	-0.352314352	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Lung seven transmembrane receptor	Transmembrane protein 87B (Precursor) GN=TMEM87B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 87B [Trichechus manatus latirostris]
ENSG00000153233(PTPRR)	--	0.235523555	11	0.384591064	18	0.224241617	9	0.533217084	25	0.354034446	16	1.085609278	51	0.912310889	1.053795306	normal	--	--	--	0.000100062	2.31300275	up	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K04458|0|nle:100583678|PTPRR; protein tyrosine phosphatase, receptor type, R; K04458 receptor-type tyrosine-protein phosphatase R [EC:3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain"	Receptor-type tyrosine-protein phosphatase R (Precursor) GN=PTPRR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase R isoform X1 [Loxodonta africana]
ENSG00000153234(NR4A2)	--	1.64528019	80	2.637079791	151	1.141464975	70	0.250530509	16	0.59071783	38	1.120670711	57	3.42E-07	-2.246278214	down	8.58E-10	-1.969462484	down	0.960421004	-0.297548151	normal	0.076194904	-1.457946135	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08558|0|phd:102322653|NR4A2; nuclear receptor subfamily 4, group A, member 2; K08558 nuclear receptor subfamily 4 group A member 2 (A)"	--	[K]	Transcription	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Nuclear receptor subfamily 4 group A member 2 GN=NR4A2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor subfamily 4 group A member 2 isoform 2 [Ovis aries] 
ENSG00000153237(CCDC148)	--	0.606059823	20	0.064587951	3	0.215927082	9	0.268592489	9	0.150737503	7	0.376127634	12	0.944539841	-1.058875335	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 148 GN=CCDC148 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 148 [Loxodonta africana]
ENSG00000153246(PLA2R1)	--	3.727118	508	3.689838441	468	3.1001467	405	1.652264744	269	1.997901358	319	1.54478274	224	8.31E-05	-0.944060525	normal	0.216649891	-0.572124748	normal	0.001510141	-0.858341132	normal	5.81E-05	-0.788025397	normal	--	--	--	"K06560|0|pps:100988259|PLA2R1; phospholipase A2 receptor 1, 180kDa; K06560 mannose receptor, C type (A)"	Phagosome (ko04145);; Tuberculosis (ko05152)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; Fibronectin type II domain;; UL45 protein	Soluble secretory phospholipase A2 receptor (Precursor) GN=PLA2R1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: secretory phospholipase A2 receptor isoform X1 [Equus przewalskii]
ENSG00000153250(RBMS1)	--	19.98631673	1357	27.107707	1841	22.83271799	1502	16.06694095	1082	14.49393576	957	18.13082869	1217	0.829923738	-0.357098549	normal	2.47E-06	-0.964206269	normal	0.900923269	-0.311497986	normal	0.014041825	-0.5506285	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"RNA-binding motif, single-stranded-interacting protein 1 GN=RBMS1 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: RNA-binding motif, single-stranded-interacting protein 1 isoform X2 [Ochotona princeps]"
ENSG00000153253(SCN3A)	--	0.17073243	27	0.161299395	18	0.251048292	14	0.155267234	25	0.468409677	57	0.185392082	27	0.985959729	-0.133940092	normal	0.012587587	1.564037423	normal	0.93746089	0.870504945	normal	0.339904189	0.864272154	normal	--	--	Cellular Component: voltage-gated sodium channel complex (GO:0001518);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated sodium channel activity (GO:0005248);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04836|0|pps:100978393|SCN3A; sodium channel, voltage-gated, type III, alpha subunit; K04836 voltage-gated sodium channel type III alpha (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Sodium ion transport-associated;; Domain of unknown function (DUF3451);; Polycystin cation channel	Sodium channel protein type 3 subunit alpha GN=SCN3A OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel protein type 3 subunit alpha isoform X1 [Galeopterus variegatus]
ENSG00000153283(CD96)	--	0	0	0	0	0	0	0.243449068	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06517|0|pon:100437719|CD96; CD96 molecule; K06517 CD96 antigen (A)	--	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	T-cell surface protein tactile (Precursor) GN=CD96 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: T-cell surface protein tactile [Mustela putorius furo] 
ENSG00000153291(SLC25A27)	--	1.73260725	131	2.700024962	111	3.118176	171	1.307912508	88	1.355949616	92	1.719378629	124	0.639055197	-0.596231032	normal	0.943116597	-0.28796402	normal	0.782291791	-0.46707566	normal	0.220224069	-0.461557998	normal	--	--	--	"K15112|0|pps:100996093|SLC25A27; solute carrier family 25, member 27; K15112 solute carrier family 25 (mitochondrial uncoupling protein), member 27 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial uncoupling protein 4 GN=SLC25A27 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial uncoupling protein 4 isoform X1 [Galeopterus variegatus]
ENSG00000153294(ADGRF4)	--	4.174598346	225	4.687672411	241	4.417922814	236	7.749570911	432	11.10514503	608	9.321218324	507	0.000443345	0.905736932	normal	1.24E-09	1.308264279	up	1.89E-06	1.090027763	up	9.74E-07	1.119332248	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08457|0|hsa:221393|GPR115, PGR18, ADGRF4; G protein-coupled receptor 115; K08457 G protein-coupled receptor 115 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Latrophilin/CL-1-like GPS domain	Probable G-protein coupled receptor 115 (Precursor) GN=GPR115 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 115 [Galeopterus variegatus]
ENSG00000153310(FAM49B)	--	71.47922285	2260	66.599091	2272	68.788604	2218	70.0692258	2298	64.6739963	2229	63.85184187	2175	0.988030974	-0.006771673	normal	0.987022025	-0.048959874	normal	0.987399119	-0.036510268	normal	0.908958444	-0.031689594	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1394)	Protein FAM49B GN=FAM49B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM49B-like isoform X1 [Echinops telfairi]
ENSG00000153317(ASAP1)	--	39.46736003	5238	43.6314	5654	43.86521891	5810	38.51104429	5099	38.109101	5010	41.6348027	5633	0.992933274	-0.069613288	normal	0.986037551	-0.195832152	normal	0.993724747	-0.052912146	normal	0.640061201	-0.10620811	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; 	"K12488|0|cjc:100407033|ASAP1; ArfGAP with SH3 domain, ankyrin repeat and PH domain 1; K12488 Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein (A)"	Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Ankyrin repeats (3 copies);; SH3 domain;; Variant SH3 domain;; Ankyrin repeat;; PH domain;; Variant SH3 domain;; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 GN=ASAP1 OS=Homo sapiens (Human) PE=1 SV=4"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 isoform 2 [Ceratotherium simum simum]"
ENSG00000153339(TRAPPC8)	--	7.528796446	712	8.148885508	786	7.963201723	721	8.459819186	775	7.784262982	745	8.85888734	846	0.972437027	0.091297944	normal	0.971676612	-0.098520709	normal	0.946457196	0.221936794	normal	0.79583903	0.071500818	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	ER-Golgi trafficking TRAPP I complex 85 kDa subunit	Trafficking protein particle complex subunit 8 GN=TRAPPC8 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 8 isoformX1 [Equus caballus] 
ENSG00000153347(FAM81B)	--	0	0	0	0	0	0	0	0	0	0	0.037253652	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM81B GN=FAM81B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM81B [Canis lupus familiaris]
ENSG00000153391(INO80C)	--	11.58838077	150	11.80399815	163	12.04649629	138	20.93222012	312	24.40052625	366	22.38513885	322	0.00015942	1.01836776	up	4.87E-06	1.138313139	up	1.66E-06	1.205201187	up	4.06E-07	1.127542551	up	[S]	Function unknown	--	K11667|1.80343e-140|pps:100985867|INO80C; INO80 complex subunit C; K11667 INO80 complex subunit C (A)	--	[S]	Function unknown	YL1 nuclear protein C-terminal domain	INO80 complex subunit C GN=INO80C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: INO80 complex subunit C isoform 1 [Ceratotherium simum simum]
ENSG00000153395(LPCAT1)	--	40.4193	2734	45.2246	3096	47.2579	3245	93.1614	6355	75.3819	5103	84.8933	5780	6.73E-11	1.185597217	up	0.007430513	0.699244966	normal	0.000122897	0.824267816	normal	5.20E-11	0.904219045	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	"Molecular Function: calcium ion binding (GO:0005509);; Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13510|0|hsa:79888|LPCAT1, AYTL2, PFAAP3, lpcat; lysophosphatidylcholine acyltransferase 1 (EC:2.3.1.23 2.3.1.67); K13510 lysophosphatidylcholine acyltransferase / lyso-PAF acetyltransferase [EC:2.3.1.23 2.3.1.67] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565)	[I]	Lipid transport and metabolism	Acyltransferase;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair	Lysophosphatidylcholine acyltransferase 1 GN=LPCAT1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: lysophosphatidylcholine acyltransferase 1 [Orcinus orca]
ENSG00000153404(PLEKHG4B)	--	0.569067144	63	0.299260486	50	0.335216641	42	1.157883945	70	0.921474998	79	0.3676476	52	0.9735599	0.118430097	normal	0.80792514	0.623381548	normal	0.970119751	0.290417138	normal	0.547466088	0.35260601	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Pleckstrin homology domain-containing family G member 4B GN=PLEKHG4B OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family G member 4B isoform X1 [Canis lupus familiaris]
ENSG00000153406(NMRAL1)	--	32.32079325	711	30.69562676	691	28.9638815	668	28.25901997	627	30.21424131	657	26.70457854	590	0.947492476	-0.211728736	normal	0.970447689	-0.094007869	normal	0.954590833	-0.186973874	normal	0.482291886	-0.164916237	normal	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	Biological Process: potassium ion transport (GO:0006813);; 	--	--	--	--	NmrA-like family;; NADH(P)-binding;; short chain dehydrogenase;; TrkA-N domain	NmrA-like family domain-containing protein 1 GN=NMRAL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nmrA-like family domain-containing protein 1 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000153443(UBALD1)	--	31.62380909	646	29.83634873	621	26.94234845	697	32.9304522	719	34.1424758	693	39.29160346	806	0.967898343	0.12334719	normal	0.965023387	0.1365207	normal	0.953158042	0.200924016	normal	0.509389078	0.154774214	normal	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: UBA-like domain-containing protein 1 [Leptonychotes weddellii]
ENSG00000153446(C16orf89)	--	0	0	0	0	0	0	0.0305921	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative binding domain	UPF0764 protein C16orf89 (Precursor) GN=C16orf89 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0764 protein C16orf89 homolog isoform X1 [Mustela putorius furo] 
ENSG00000153487(ING1)	--	3.452979633	168	6.3176084	128	2.121742214	130	3.819605215	176	3.575936059	166	2.95982847	172	0.966895592	0.035960618	normal	0.899277059	0.349973194	normal	0.868215977	0.391632593	normal	0.530077875	0.249468063	normal	--	--	--	--	--	[B]	Chromatin structure and dynamics	Inhibitor of growth proteins N-terminal histone-binding;; PHD-finger	Inhibitor of growth protein 1 GN=ING1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: inhibitor of growth protein 1 [Odobenus rosmarus divergens]
ENSG00000153495(TEX29)	--	0	0	0	0	0	0	0	0	0	0	0.225051	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testis-expressed sequence 29 protein GN=TEX29 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 29 protein [Ursus maritimus]
ENSG00000153531(ADPRHL1)	--	11.31899087	307	8.866395288	249	10.0608024	295	8.403792391	296	9.738834782	266	9.737312865	281	0.964772123	-0.083050404	normal	0.963907363	0.073422468	normal	0.965044317	-0.07802638	normal	0.941236754	-0.034863869	normal	--	--	--	--	--	--	--	ADP-ribosylglycohydrolase	[Protein ADP-ribosylarginine] hydrolase-like protein 1 GN=ADPRHL1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: collagen alpha-1(I) chain-like isoform X2 [Equus przewalskii]
ENSG00000153551(CMTM7)	--	18.30684982	361	15.51178117	329	16.54153622	321	14.695304	315	17.49009637	341	10.009392	230	0.936923746	-0.2264465	normal	0.967134251	0.030121599	normal	0.576305909	-0.486510281	normal	0.46834268	-0.212460656	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	CKLF-like MARVEL transmembrane domain-containing protein 7 GN=CMTM7 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: CKLF-like MARVEL transmembrane domain-containing protein 7 isoform 1 [Orcinus orca]
ENSG00000153558(FBXL2)	--	5.089187	301	5.891396	330	5.632903	280	8.442404888	379	5.462322239	286	7.4389801	346	0.895609572	0.300233921	normal	0.936302925	-0.226760066	normal	0.901227566	0.295614964	normal	0.696556357	0.128433986	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10268|0|pps:100978208|FBXL2; F-box and leucine-rich repeat protein 2; K10268 F-box and leucine-rich repeat protein 2/20 (A)	--	[R]	General function prediction only	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; F-box-like;; Leucine rich repeat;; Leucine Rich Repeat;; F-box domain	F-box/LRR-repeat protein 2 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 2 [Mustela putorius furo] 
ENSG00000153560(UBP1)	--	26.68352875	1858	28.03619783	1925	30.56483717	2110	35.29766505	2440	32.50473052	2228	30.44804706	2108	0.852865623	0.362036458	normal	0.974087391	0.189325881	normal	0.987344812	-0.009652652	normal	0.338795405	0.179979619	normal	--	--	--	K09275|0|ptr:460257|UBP1; upstream binding protein 1 (LBP-1a); K09275 transcription factor CP2 and related proteins (A)	--	[K]	Transcription	CP2 transcription factor	Upstream-binding protein 1 GN=UBP1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: upstream-binding protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000153561(RMND5A)	--	9.88227	990	10.726	1081	8.96654	889	7.13734	720	8.32048	830	11.6593	1166	0.380889244	-0.489369064	normal	0.723848248	-0.401966019	normal	0.768771298	0.382451278	normal	0.735795444	-0.144140895	normal	[R]	General function prediction only	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	CTLH/CRA C-terminal to LisH motif domain;; RING-type zinc-finger	Protein RMD5 homolog A GN=RMND5A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein RMD5 homolog A [Trichechus manatus latirostris]
ENSG00000153563(CD8A)	--	0.34191752	17	0.577674135	22	0.135327215	6	0.213412353	8	0.345114825	17	0.297751047	15	--	--	--	0.984223952	-0.364794124	normal	--	--	--	--	--	--	--	--	--	"K06458|1.59817e-127|hsa:925|CD8A, CD8, Leu2, MAL, p32; CD8a molecule; K06458 CD8A antigen, alpha polypeptide (A)"	Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Hematopoietic cell lineage (ko04640);; T cell receptor signaling pathway (ko04660);; Primary immunodeficiency (ko05340)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain	T-cell surface glycoprotein CD8 alpha chain (Precursor) GN=CD8A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: T-cell surface glycoprotein CD8 alpha chain [Galeopterus variegatus]
ENSG00000153574(RPIA)	--	11.9447	378	14.4609	475	12.4858	403	9.68598	312	10.3706	326	8.08761	256	0.890142789	-0.306299563	normal	0.241226548	-0.562307469	normal	0.06922306	-0.659793848	normal	0.016903837	-0.512327504	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: ribose-5-phosphate isomerase activity (GO:0004751);; Biological Process: pentose-phosphate shunt, non-oxidative branch (GO:0009052);; "	K01807|0|pon:100447020|RPIA; ribose 5-phosphate isomerase A; K01807 ribose 5-phosphate isomerase A [EC:5.3.1.6] (A)	Pentose phosphate pathway (ko00030);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Ribose 5-phosphate isomerase A (phosphoriboisomerase A)	Ribose-5-phosphate isomerase GN=RPIA OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: ribose-5-phosphate isomerase [Odobenus rosmarus divergens]
ENSG00000153684(GOLGA8F)	--	0.112645894	11	0.0809715	8	0.100932657	9	0.081394275	8	0.059586644	5	0.172681549	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8C GN=GOLGA8CP OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000153707(PTPRD)	--	0.00934252	1	0.015013375	2	0.007445858	0	0.5152648	27	0.478027208	42	0.281057413	49	0.000579503	3.471273636	up	7.29E-07	3.614504878	up	1.03E-10	5.057813369	up	1.17E-11	5.275363141	up	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K06777|0|nle:100591501|PTPRD; protein tyrosine phosphatase, receptor type, D; K06777 receptor-type tyrosine-protein phosphatase delta [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Interferon-alpha/beta receptor, fibronectin type III;; Dual specificity phosphatase, catalytic domain;; Immunoglobulin V-set domain;; Tyrosine phosphatase family;; Inositol hexakisphosphate;; CD80-like C2-set immunoglobulin domain"	Receptor-type tyrosine-protein phosphatase delta (Precursor) GN=PTPRD OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase delta isoform X8 [Equus caballus]
ENSG00000153714(LURAP1L)	--	10.047163	339	11.408549	382	8.908375	307	5.910098	197	7.231454	238	9.907965	347	0.007126294	-0.809048648	normal	0.042339576	-0.700489796	normal	0.953801615	0.16762844	normal	0.23979163	-0.41439765	normal	--	--	--	--	--	--	--	Leucine rich adaptor protein	Leucine rich adaptor protein 1-like GN=LURAP1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: leucine rich adaptor protein 1-like [Loxodonta africana]
ENSG00000153721(CNKSR3)	--	2.769439	245	3.078224	292	3.035834	354	2.99540399	298	2.988335357	269	2.619203	230	0.929071312	0.250273465	normal	0.957386734	-0.139038242	normal	0.140672983	-0.627057382	normal	0.57584589	-0.182321151	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	--	--	[F]	Nucleotide transport and metabolism	Protein of unknown function (DUF1170);; Connector enhancer of kinase suppressor of ras;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; PDZ domain (Also known as DHR or GLGF)	Connector enhancer of kinase suppressor of ras 3 GN=CNKSR3 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: connector enhancer of kinase suppressor of ras 3 [Ceratotherium simum simum]
ENSG00000153767(GTF2E1)	--	7.864098023	417	7.579684688	409	8.580819	454	7.356711867	396	8.42799	439	7.918598337	396	0.964577157	-0.10498221	normal	0.966435482	0.080406542	normal	0.945231891	-0.204752421	normal	0.817059731	-0.077269546	normal	[K]	Transcription	--	"K03136|0|hsa:2960|GTF2E1, FE, TF2E1, TFIIE-A; general transcription factor IIE, polypeptide 1, alpha 56kDa; K03136 transcription initiation factor TFIIE subunit alpha (A)"	Basal transcription factors (ko03022);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	C-terminal general transcription factor TFIIE alpha;; TFIIE alpha subunit;; TFIIB zinc-binding	General transcription factor IIE subunit 1 GN=GTF2E1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: general transcription factor IIE subunit 1 [Ailuropoda melanoleuca] 
ENSG00000153774(CFDP1)	--	37.84768266	1267	34.985318	1217	35.06792284	1212	37.728084	1368	42.879428	1439	42.09439032	1478	0.980460231	0.07972639	normal	0.957751593	0.220059152	normal	0.929718828	0.277650923	normal	0.311077887	0.192351689	normal	--	--	--	--	--	[S]	Function unknown	Bucentaur or craniofacial development	Craniofacial development protein 1 GN=CFDP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: craniofacial development protein 1 [Ceratotherium simum simum]
ENSG00000153779(TGIF2LX)	--	0.0655098	1	0	0	0.128316	1	0	0	0	0	0.06450303	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein TGIF2LX GN=TGIF2LX OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox protein TGIF2LX [Canis lupus familiaris]
ENSG00000153786(ZDHHC7)	--	39.67614108	2142	44.649266	2327	36.71433013	2055	39.2821135	2250	36.41162578	2002	45.49026006	2427	0.987318406	0.040106189	normal	0.962649231	-0.238288651	normal	0.965374068	0.231587282	normal	0.970713142	0.012692889	normal	--	--	--	"K18932|0|hsa:55625|ZDHHC7, DHHC7, SERZ-B, SERZ1, ZNF370; zinc finger, DHHC-type containing 7 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC7 GN=ZDHHC7 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	hypothetical protein PANDA_001248 [Ailuropoda melanoleuca]
ENSG00000153790(C7orf31)	--	2.790727737	116	1.823225916	72	4.319476577	114	1.686519247	80	3.904407219	99	3.632908584	99	0.756698367	-0.557931287	normal	0.902965985	0.430269572	normal	0.958087253	-0.208849234	normal	0.813067828	-0.139523519	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4555)	Uncharacterized protein C7orf31 GN=C7orf31 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C7orf31 homolog [Ceratotherium simum simum]
ENSG00000153814(JAZF1)	--	5.671292303	189	3.317595097	135	5.36626087	222	3.44339	158	6.343780005	189	3.090369002	106	0.924703077	-0.28674038	normal	0.773042171	0.459630393	normal	0.000399541	-1.064057662	down	0.580229312	-0.290786687	normal	[KD]	"Transcription;; Cell cycle control, cell division, chromosome partitioning"	--	--	--	[KD]	"Transcription;; Cell cycle control, cell division, chromosome partitioning"	"Zinc finger, C2H2 type"	Juxtaposed with another zinc finger protein 1 GN=JAZF1 OS=Homo sapiens (Human) PE=1 SV=2	DK	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	PREDICTED: juxtaposed with another zinc finger protein 1 [Orycteropus afer afer]
ENSG00000153815(CMIP)	--	65.14857423	5542	60.492707	5059	67.84826207	5703	52.4849327	4413	52.92192878	4430	45.917416	3936	0.910549222	-0.359367293	normal	0.98248526	-0.212904026	normal	0.243158786	-0.543107872	normal	0.01979436	-0.372796719	normal	--	--	--	--	--	--	--	--	C-Maf-inducing protein GN=CMIP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: c-Maf-inducing protein [Chrysochloris asiatica]
ENSG00000153820(SPHKAP)	--	0.01326869	2	0	0	0	0	0	0	0.006411418	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	A-kinase anchor protein 110 kDa (AKAP 110)	A-kinase anchor protein SPHKAP GN=SPHKAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: A-kinase anchor protein SPHKAP isoform X2 [Equus przewalskii]
ENSG00000153822(KCNJ16)	--	0.125140446	4	0.069749489	4	0	0	0.752235418	48	0.998737434	65	1.350941721	77	1.15E-06	3.135380723	up	2.13E-10	3.574656335	up	0	5.694053179	up	1.51E-14	4.547407176	up	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05009|0|ptr:468311|KCNJ16; potassium inwardly-rectifying channel, subfamily J, member 16; K05009 potassium inwardly-rectifying channel subfamily J member 16 (A)"	Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	Inward rectifier potassium channel 16 GN=KCNJ16 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: inward rectifier potassium channel 16 isoform X1 [Equus caballus] 
ENSG00000153823(PID1)	--	5.720713467	260	6.173084619	263	6.546226	272	5.1501107	233	7.537977451	321	7.035012399	276	0.949679017	-0.187840566	normal	0.920403654	0.26470431	normal	0.967419782	0.012700076	normal	0.928019045	0.041634842	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Phosphotyrosine interaction domain (PTB/PID);; Phosphotyrosine interaction domain (PTB/PID)	"PTB-containing, cubilin and LRP1-interacting protein GN=PID1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: PTB-containing, cubilin and LRP1-interacting protein [Galeopterus variegatus]"
ENSG00000153827(TRIP12)	--	44.40980271	5864	44.11345623	6243	43.83950144	6316	30.89947647	4298	33.244297	4692	30.95664235	4411	0.562154892	-0.478904649	normal	0.777665256	-0.433341473	normal	0.332923675	-0.526045298	normal	0.00164566	-0.480173478	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	"K10590|0|hsa:9320|TRIP12, TRIP-12, ULF; thyroid hormone receptor interactor 12; K10590 E3 ubiquitin-protein ligase TRIP12 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase)	E3 ubiquitin-protein ligase TRIP12 GN=TRIP12 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIP12 isoform X5 [Loxodonta africana]
ENSG00000153832(FBXO36)	--	3.048759	144	2.3488403	107	2.675834	123	1.203411	57	1.763765	83	1.065692	48	6.70E-05	-1.344237858	down	0.915977868	-0.381710943	normal	0.000302848	-1.338544062	down	0.003983556	-1.01366038	down	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10312|4.03865e-125|hsa:130888|FBXO36, Fbx36; F-box protein 36; K10312 F-box protein 36 (A)"	--	[R]	General function prediction only	F-box domain;; F-box-like	F-box only protein 36 GN=FBXO36 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: F-box only protein 36 [Leptonychotes weddellii]
ENSG00000153879(CEBPG)	--	30.893471	1958	32.577557	2103	29.87631175	1869	27.236857	1713	26.14276198	1642	33.39421	2126	0.963546521	-0.223500192	normal	0.819446077	-0.378112692	normal	0.975744996	0.177448878	normal	0.539907804	-0.134324156	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10049|3.04447e-85|pps:100989464|CEBPG; CCAAT/enhancer binding protein (C/EBP), gamma; K10049 CCAAT/enhancer binding protein (C/EBP), gamma (A)"	Tuberculosis (ko05152)	[K]	Transcription	Basic region leucine zipper;; bZIP transcription factor	CCAAT/enhancer-binding protein gamma GN=CEBPG OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: CCAAT/enhancer-binding protein gamma isoform X1 [Tupaia chinensis] 
ENSG00000153885(KCTD15)	--	24.18281645	1235	32.46040495	1492	22.54006139	1212	18.66347575	934	17.11091578	901	17.45137558	868	0.60823025	-0.433226778	normal	0.002113832	-0.748088385	normal	0.377894048	-0.489189461	normal	0.000148106	-0.564923869	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD15 GN=KCTD15 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD15 [Galeopterus variegatus]
ENSG00000153896(ZNF599)	--	8.619677	97	9.518897	92	9.0677513	91	3.3664282	42	2.6021766	49	4.322345	54	0.008546378	-1.208481099	down	0.211963407	-0.909454126	normal	0.550550634	-0.744948579	normal	0.016626372	-0.969845655	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:148103|ZNF599; zinc finger protein 599; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; CHY zinc finger"	Zinc finger protein 599 GN=ZNF599 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 599 [Balaenoptera acutorostrata scammoni]
ENSG00000153898(MCOLN2)	--	4.477292808	266	4.085598707	221	3.926730001	222	3.056237589	163	2.705548759	154	2.282797167	124	0.05486033	-0.731927921	normal	0.552195382	-0.538105991	normal	0.018954743	-0.840738972	normal	0.007914568	-0.707089686	normal	--	--	--	"K04993|0|hsa:255231|MCOLN2, TRP-ML2, TRPML2; mucolipin 2; K04993 mucolipin 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Polycystin cation channel	Mucolipin-2 GN=MCOLN2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: mucolipin-2 [Galeopterus variegatus]
ENSG00000153902(LGI4)	--	0.329000336	18	0.05227205	3	0.050713273	0	0.106509044	2	0.072325103	3	0.247980972	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	EPTP domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies)	Leucine-rich repeat LGI family member 4 (Precursor) GN=LGI4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat LGI family member 4 [Ceratotherium simum simum]
ENSG00000153904(DDAH1)	--	5.379500173	329	4.283015252	248	6.139855987	375	11.92640423	718	9.622506138	594	9.301487698	566	3.41E-07	1.091530642	up	1.61E-08	1.233685984	up	0.146245553	0.583690937	normal	1.87E-06	0.95874022	normal	[E]	Amino acid transport and metabolism	--	K01482|0|mcf:102134245|DDAH1; dimethylarginine dimethylaminohydrolase 1; K01482 dimethylargininase [EC:3.5.3.18] (A)	--	--	--	Amidinotransferase	"N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 GN=DDAH1 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 [Elephantulus edwardii]"
ENSG00000153914(SREK1)	--	13.25909142	1652	15.16521595	1819	13.39500513	1645	14.53463419	1889	14.656121	1647	16.53154143	1867	0.976216568	0.162435403	normal	0.97536903	-0.164587668	normal	0.974274304	0.174192493	normal	0.821676867	0.057343163	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13165|0|mcf:101867067|uncharacterized LOC101867067; K13165 splicing factor, arginine/serine-rich 12 (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing regulatory glutamine/lysine-rich protein 1 GN=SREK1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: splicing regulatory glutamine/lysine-rich protein 1 [Loxodonta africana]
ENSG00000153922(CHD1)	--	11.224859	1607	11.3185619	1589	11.613575	1607	10.810484	1573	12.094509	1733	10.93594065	1565	0.983491333	-0.061623968	normal	0.981320193	0.103631512	normal	0.984003156	-0.046454413	normal	1	-0.000854759	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K11367|0|hsa:1105|CHD1; chromodomain helicase DNA binding protein 1 (EC:3.6.4.12); K11367 chromodomain-helicase-DNA-binding protein 1 [EC:3.6.4.12] (A)	--	[K]	Transcription	"SNF2 family N-terminal domain;; Domain of unknown function (DUF4208);; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Chromodomain-helicase-DNA-binding protein 1 GN=CHD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: chromodomain-helicase-DNA-binding protein 1 isoform X2 [Leptonychotes weddellii]
ENSG00000153930(ANKFN1)	--	0.062534871	4	0	0	0.020193982	0	0.027429027	1	0.05395103	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Fibronectin type III domain;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies)	Ankyrin repeat and fibronectin type-III domain-containing protein 1 GN=ANKFN1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and fibronectin type-III domain-containing protein 1 isoform X1 [Tupaia chinensis]
ENSG00000153933(DGKE)	--	4.062980761	371	3.897836716	408	3.985038992	277	3.987576864	385	3.965755663	379	4.132865735	408	0.969023211	0.022515464	normal	0.960778771	-0.127308116	normal	0.310957754	0.547912139	normal	0.677626342	0.12874185	normal	--	--	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|hsa:8526|DGKE, DAGK5, DAGK6, DGK, NPHS7; diacylglycerol kinase, epsilon 64kDa (EC:2.7.1.107); K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Diacylglycerol kinase epsilon GN=DGKE OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: diacylglycerol kinase epsilon [Camelus bactrianus] 
ENSG00000153936(HS2ST1)	--	23.00419454	1781	22.72310327	1773	21.43451162	1656	16.02277752	1293	19.14412815	1415	17.71255034	1452	0.367561294	-0.49229666	normal	0.866890094	-0.346485438	normal	0.967354589	-0.197759644	normal	0.029448869	-0.345642565	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	K02513|0|pps:100984243|HS2ST1; heparan sulfate 2-O-sulfotransferase 1; K02513 heparan sulfate 2-O-sulfotransferase HS2ST1 [EC:2.8.2.-] (A)	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase family	Heparan sulfate 2-O-sulfotransferase 1 GN=HS2ST1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan sulfate 2-O-sulfotransferase 1 [Ceratotherium simum simum]
ENSG00000153944(MSI2)	--	22.04628947	1468	22.8250171	1568	22.70087623	1522	23.34125066	1613	25.79445514	1650	28.83861791	1982	0.980645354	0.10495739	normal	0.983580851	0.052064954	normal	0.819590881	0.372372033	normal	0.339233462	0.181950956	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K14411|0|ocu:100342991|MSI2; musashi RNA-binding protein 2; K14411 RNA-binding protein Musashi (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein Musashi homolog 2 GN=MSI2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein Musashi homolog 2 [Oryctolagus cuniculus]
ENSG00000153956(CACNA2D1)	--	8.019017051	949	7.813124303	922	7.55916282	876	5.544218017	661	5.163066635	567	6.200494971	700	0.167555138	-0.551513699	normal	0.006442763	-0.72132014	normal	0.859609735	-0.331226313	normal	0.001017047	-0.531949001	normal	--	--	--	"K04858|0|mcf:102131750|CACNA2D1; calcium channel, voltage-dependent, alpha 2/delta subunit 1; K04858 voltage-dependent calcium channel alpha-2/delta-1 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Neuronal voltage-dependent calcium channel alpha 2acd;; VWA N-terminal;; Cache domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Voltage-dependent calcium channel subunit delta-1 (Precursor) GN=CACNA2D1 OS=Homo sapiens (Human) PE=1 SV=3	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-1 isoform X2 [Mustela putorius furo] 
ENSG00000153975(ZUFSP)	--	3.331915087	131	3.952317284	153	4.075644608	154	4.671982575	184	4.707188005	186	3.807319935	147	0.788008345	0.45478748	normal	0.934552301	0.25802826	normal	0.966048903	-0.074655187	normal	0.592766436	0.217567369	normal	--	--	--	--	--	[S]	Function unknown	Peptidase family C78;; C2H2-type zinc finger	Zinc finger with UFM1-specific peptidase domain protein GN=ZUFSP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger with UFM1-specific peptidase domain protein [Galeopterus variegatus]
ENSG00000153976(HS3ST3A1)	--	0	0	0.097175158	1	0	0	0.0472947	2	0.56879	8	0.097101651	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	K07809|0|pps:100974193|HS3ST3A1; heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1; K07809 [heparan sulfate]-glucosamine 3-sulfotransferase 3 [EC:2.8.2.30] (A)	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase domain	Heparan sulfate glucosamine 3-O-sulfotransferase 3A1 GN=HS3ST3A1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan sulfate glucosamine 3-O-sulfotransferase 3A1 [Pteropus alecto] 
ENSG00000153982(GDPD1)	--	3.787682	93	1.793777441	46	2.927954391	73	2.318609394	57	3.676083249	92	2.04956727	50	0.578493421	-0.721712277	normal	0.156915236	0.955942957	normal	0.889418743	-0.540647332	normal	0.904901829	-0.112285732	normal	[C]	Energy production and conversion	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; 	--	--	[C]	Energy production and conversion	Glycerophosphoryl diester phosphodiesterase family	Glycerophosphodiester phosphodiesterase domain-containing protein 1 GN=GDPD1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 1 isoform X1 [Panthera tigris altaica] 
ENSG00000153989(NUS1)	--	23.22546048	1520	25.07320001	1654	21.66325008	1402	23.64656623	1572	22.23878086	1454	21.92723487	1436	0.9842631	0.017680058	normal	0.964857487	-0.20715634	normal	0.983281199	0.02624998	normal	0.822776504	-0.058112735	normal	[I]	Lipid transport and metabolism	"Molecular Function: transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765);; "	--	--	[I]	Lipid transport and metabolism	Putative undecaprenyl diphosphate synthase	Dehydrodolichyl diphosphate syntase complex subunit NUS1 {ECO:0000305} GN=NUS1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	nogo-B receptor [Bos taurus] 
ENSG00000153993(SEMA3D)	--	0.540043526	57	0.465704055	48	0.645060471	69	0.114465003	12	0.130579664	13	0.219775015	23	8.65E-05	-2.141162242	down	0.0072363	-1.790494826	down	0.003536668	-1.532316297	down	0.000109536	-1.876664415	down	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06840|0|hsa:223117|SEMA3D, Sema-Z2, coll-2; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; K06840 semaphorin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Immunoglobulin V-set domain	Semaphorin-3D (Precursor) GN=SEMA3D OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: semaphorin-3D [Galeopterus variegatus]
ENSG00000154001(PPP2R5E)	--	25.3476	1647	25.21350763	1714	24.53818	1755	24.72248297	1801	24.905071	1820	25.94477055	1770	0.982483166	0.098037889	normal	0.984120101	0.065089048	normal	0.985692503	0.00398347	normal	0.832628963	0.054378858	normal	--	--	Cellular Component: protein phosphatase type 2A complex (GO:0000159);; Biological Process: signal transduction (GO:0007165);; Molecular Function: protein phosphatase regulator activity (GO:0019888);; 	"K11584|0|fab:101822058|PPP2R5E; protein phosphatase 2, regulatory subunit B', epsilon isoform; K11584 serine/threonine-protein phosphatase 2A regulatory subunit B' (A)"	mRNA surveillance pathway (ko03015);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261)	[T]	Signal transduction mechanisms	Protein phosphatase 2A regulatory B subunit (B56 family)	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform GN=PPP2R5E OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform [Myotis brandtii]
ENSG00000154016(GRAP)	--	0.154349	6	0.0878742	2	0.074144	2	0.102297	4	0.300491	11	0.2309641	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; SH2 domain;; Bacterial SH3 domain	GRB2-related adapter protein GN=GRAP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: GRB2-related adapter protein [Tupaia chinensis] 
ENSG00000154025(SLC5A10)	--	0.119896	4	0.08873746	3	0.14442682	4	0.06015159	4	0.408587852	14	0.266951638	10	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14390|0|mcf:102128088|SLC5A10; solute carrier family 5 (sodium/sugar cotransporter), member 10; K14390 solute carrier family 5 (sodium/glucose cotransporter), member 10 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium/glucose cotransporter 5 GN=SLC5A10 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/glucose cotransporter 5 isoform X1 [Leptonychotes weddellii]
ENSG00000154027(AK5)	--	3.437032626	178	2.748075001	142	4.5378869	199	2.710410657	134	2.757968	138	1.797323735	101	0.815010148	-0.436121393	normal	0.965757306	-0.061979611	normal	0.003442515	-0.976092811	normal	0.133293023	-0.498025402	normal	[F]	Nucleotide transport and metabolism	--	K00939|0|pps:100981802|AK5; adenylate kinase 5; K00939 adenylate kinase [EC:2.7.4.3] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	Adenylate kinase;; AAA domain;; AAA domain;; AAA domain;; Thymidylate kinase;; Zeta toxin;; Cytidylate kinase-like family;; Deoxynucleoside kinase	Adenylate kinase isoenzyme 5 GN=AK5 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: adenylate kinase isoenzyme 5 isoform X2 [Canis lupus familiaris]
ENSG00000154040(CABYR)	--	6.730979119	202	5.795104206	183	7.001020886	230	5.193815045	167	5.02211395	154	5.198838645	163	0.914653745	-0.302801852	normal	0.931273832	-0.267922887	normal	0.634261543	-0.501119672	normal	0.255595881	-0.366526764	normal	--	--	--	--	--	--	--	Regulatory subunit of type II PKA R-subunit	Calcium-binding tyrosine phosphorylation-regulated protein GN=CABYR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: calcium-binding tyrosine phosphorylation-regulated protein [Tupaia chinensis]
ENSG00000154059(IMPACT)	--	9.002433969	533	7.22197345	429	9.219098905	479	9.826969464	558	9.787594306	569	8.884975797	524	0.972081981	0.035198162	normal	0.771704112	0.384843015	normal	0.964739488	0.120884709	normal	0.485739364	0.174959749	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Uncharacterized protein family UPF0029;; RWD domain	Protein IMPACT GN=IMPACT OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein IMPACT isoform X2 [Leptonychotes weddellii]
ENSG00000154065(ANKRD29)	--	11.56117863	713	15.62957673	707	12.125901	593	7.693457196	446	8.75779619	531	9.582199585	542	0.010570207	-0.705748575	normal	0.631458794	-0.433351324	normal	0.963686653	-0.137663338	normal	0.020616613	-0.427104449	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 29 GN=ANKRD29 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 29 isoform X2 [Tupaia chinensis]
ENSG00000154079(SDHAF4)	--	6.450623327	125	5.12149072	96	6.285696177	122	6.825324	133	4.780716554	103	5.206679954	106	0.967913733	0.057975025	normal	0.96815699	0.078911246	normal	0.956730445	-0.208335386	normal	0.977447219	-0.025959493	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1674)	"Succinate dehydrogenase assembly factor 4, mitochondrial {ECO:0000303|PubMed:24954416} (Precursor) OS=Homo sapiens (Human) PE=2 SV=1"	S	Function unknown	PREDICTED: UPF0369 protein C6orf57 homolog [Galeopterus variegatus]
ENSG00000154096(THY1)	--	21.55352484	709	14.01670904	596	16.09930812	637	8.772628483	319	14.61279215	478	5.258902415	177	1.73E-08	-1.1791452	down	0.848896377	-0.338766252	normal	0	-1.846937497	down	0.002265563	-1.017724462	down	--	--	--	K06514|1.5578e-85|ptr:451611|THY1; Thy-1 cell surface antigen; K06514 Thy-1 cell surface antigen (A)	Leukocyte transendothelial migration (ko04670)	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain	Thy-1 membrane glycoprotein (Precursor) GN=THY1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: thy-1 membrane glycoprotein [Orcinus orca] 
ENSG00000154099(DNAAF1)	--	0.0160735	1	0.088234372	5	0.051772332	2	0.122724798	7	0.0883397	4	0.2760714	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Dynein assembly factor 1, axonemal GN=DNAAF1 OS=Homo sapiens (Human) PE=1 SV=5"	Z	Cytoskeleton	"PREDICTED: dynein assembly factor 1, axonemal [Balaenoptera acutorostrata scammoni]"
ENSG00000154102(C16orf74)	--	10.73047983	145	5.13977765	73	7.413324001	111	8.416952169	108	9.561702138	120	7.697393522	101	0.834972156	-0.45030284	normal	0.501306699	0.684476144	normal	0.965150276	-0.14246028	normal	0.984925516	-0.021138819	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4597)	Uncharacterized protein C16orf74 GN=C16orf74 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C16orf74 homolog [Mustela putorius furo]
ENSG00000154114(TBCEL)	--	5.161379963	383	7.004045841	450	5.686982639	384	5.764605495	421	5.772143215	386	5.86075051	458	0.96444993	0.105240821	normal	0.92994042	-0.241872059	normal	0.929067303	0.24506506	normal	0.929516481	0.034650571	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Ubiquitin-like domain	Tubulin-specific chaperone cofactor E-like protein GN=TBCEL OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin-specific chaperone cofactor E-like protein isoform X1 [Ochotona princeps] 
ENSG00000154118(JPH3)	--	0.899468	72	0.500901	41	0.710993	59	0.64346	52	0.971918	78	0.867706	71	0.915361112	-0.488005615	normal	0.400161494	0.882456227	normal	0.964877418	0.252895987	normal	0.761457182	0.204782622	normal	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat	Junctophilin-3 GN=JPH3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: junctophilin-3 [Ceratotherium simum simum]
ENSG00000154122(ANKH)	--	8.11684	433	8.68741	452	5.6766	331	9.05986	521	9.24701	531	8.6216	491	0.933942522	0.235322034	normal	0.943809761	0.210312765	normal	0.235203172	0.558492205	normal	0.138758368	0.321754184	normal	--	--	Molecular Function: phosphate ion transmembrane transporter activity (GO:0015114);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: phosphate ion transmembrane transport (GO:0035435);; 	--	--	--	--	Progressive ankylosis protein (ANKH)	Progressive ankylosis protein homolog GN=ANKH OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: progressive ankylosis protein homolog [Oryctolagus cuniculus]
ENSG00000154124(OTULIN)	--	4.770252056	676	6.2065767	742	6.384917397	781	7.4355337	966	6.6271495	898	5.792974173	807	0.409939535	0.483244607	normal	0.932562483	0.253399647	normal	0.976333019	0.038880617	normal	0.173404601	0.258965357	normal	--	--	--	"K18343|0|hsa:90268|OTULIN, FAM105B, GUM; OTU deubiquitinase with linear linkage specificity (EC:3.4.19.12); K18343 ubiquitin thioesterase otulin [EC:3.4.19.12] (A)"	--	--	--	--	Ubiquitin thioesterase otulin GN=OTULIN OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: ubiquitin thioesterase otulin [Oryctolagus cuniculus]
ENSG00000154127(UBASH3B)	--	26.00399	3043	22.85175	2674	28.353	3276	18.81026	2205	16.39036	1908	16.95336	1985	0.392924279	-0.49525275	normal	0.351385393	-0.508022968	normal	0.002075125	-0.730649845	normal	4.02E-05	-0.581752319	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	--	--	[G]	Carbohydrate transport and metabolism	Histidine phosphatase superfamily (branch 1);; Variant SH3 domain;; 2'-5' RNA ligase superfamily;; SH3 domain;; UBA/TS-N domain	Ubiquitin-associated and SH3 domain-containing protein B GN=UBASH3B OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: ubiquitin-associated and SH3 domain-containing protein B [Ceratotherium simum simum]
ENSG00000154133(ROBO4)	--	0	0	0	0	0.016111165	0	0	0	0.021478623	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06784|0|pps:100988251|ROBO4; roundabout, axon guidance receptor, homolog 4 (Drosophila); K06784 roundabout, axon guidance receptor 4 (A)"	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain	Roundabout homolog 4 (Precursor) GN=ROBO4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: roundabout homolog 4 isoform X1 [Sus scrofa]
ENSG00000154134(ROBO3)	--	1.348974957	45	1.004796689	31	0.77206793	32	1.003834406	34	1.358571105	45	0.96082051	33	0.964107477	-0.418718147	normal	0.952653263	0.496046916	normal	0.983852366	0.034497232	normal	0.986486033	0.031137684	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06755|0|hsa:64221|ROBO3, HGPPS, HGPS, RBIG1, RIG1; roundabout, axon guidance receptor, homolog 3 (Drosophila); K06755 roundabout, axon guidance receptor 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Roundabout homolog 3 (Precursor) GN=ROBO3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: roundabout homolog 3 [Galeopterus variegatus]
ENSG00000154144(TBRG1)	--	11.86709	406	9.78897	408	7.940182	434	9.46218	383	9.55019	400	10.10615	473	0.963254045	-0.114521285	normal	0.967881047	-0.049809246	normal	0.964437387	0.115468189	normal	0.982012688	-0.01122747	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	--	--	[R]	General function prediction only	F/Y-rich N-terminus;; F/Y rich C-terminus	Transforming growth factor beta regulator 1 GN=TBRG1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transforming growth factor beta regulator 1 [Equus caballus] 
ENSG00000154146(NRGN)	--	3.58711149	69	3.870269	73	6.05745	117	7.62794	143	8.81746	163	6.43178	117	0.013356228	1.004659612	normal	0.001211783	1.121534424	up	0.969440186	-0.008185639	normal	0.048980534	0.687018102	normal	--	--	--	--	--	--	--	IQ calmodulin-binding motif	NEUG(55-78) GN=NRGN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: neurogranin, partial [Myotis brandtii]"
ENSG00000154153(FAM134B)	--	5.054443289	219	4.419619	219	4.2486	206	4.151939951	125	2.915852608	115	3.074935007	116	0.021939174	-0.832001638	normal	0.004123309	-0.941590962	normal	0.030014428	-0.82859302	normal	0.001382956	-0.876731218	normal	--	--	--	--	--	--	--	Reticulon	Protein FAM134B GN=FAM134B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM134B isoform 1 [Ceratotherium simum simum]
ENSG00000154162(CDH12)	--	0.032457726	2	0	0	0.016108585	0	0.127814969	10	0.110486388	6	0.112927647	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06804|0|hsa:1010|CDH12, CDHB; cadherin 12, type 2 (N-cadherin 2); K06804 cadherin 12, type 2, N-cadherin 2 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin-like	Cadherin-12 (Precursor) GN=CDH12 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: cadherin-12 isoform 2 [Canis lupus familiaris]
ENSG00000154174(TOMM70)	--	29.80286	2156	27.6148	2049	30.747834	2255	32.84368	2423	33.3861	2415	27.57556	1972	0.982654558	0.137512492	normal	0.969778915	0.215529989	normal	0.972066765	-0.20161462	normal	0.829876916	0.054513753	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K17768|0|hsa:9868|TOMM70A; translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae); K17768 mitochondrial import receptor subunit TOM70 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; MIT (microtubule interacting and transport) domain;; Anaphase-promoting complex, cyclosome, subunit 3"	Mitochondrial import receptor subunit TOM70 GN=TOMM70A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import receptor subunit TOM70 [Condylura cristata]
ENSG00000154175(ABI3BP)	--	0.08743856	9	0.090492084	8	0.024798579	1	3.250562201	181	1.630023563	142	0.648323481	56	0	4.086267162	up	0	3.89562829	up	3.22E-11	4.511111404	up	8.43E-05	4.369810435	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Fibronectin type III domain;; Interferon-alpha/beta receptor, fibronectin type III"	Target of Nesh-SH3 (Precursor) GN=ABI3BP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: target of Nesh-SH3 isoform X4 [Canis lupus familiaris]
ENSG00000154188(ANGPT1)	--	0.501304803	33	0.25862541	20	0.370123598	23	0.34543787	27	0.577215338	43	0.397582597	28	0.979995977	-0.304630171	normal	0.669196078	1.028733294	normal	0.983657676	0.259987386	normal	0.670656817	0.345787877	normal	--	--	--	K05465|0|pon:100443653|ANGPT1; angiopoietin 1; K05465 angiopoietin 1 (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; HIF-1 signaling pathway (ko04066);; PI3K-Akt signaling pathway (ko04151);; Rheumatoid arthritis (ko05323)	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-1 (Precursor) GN=ANGPT1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: angiopoietin-1 isoform X1 [Erinaceus europaeus]
ENSG00000154217(PITPNC1)	--	5.12263144	235	3.440752933	139	3.121620939	163	4.633415879	209	4.328797258	240	3.160532878	147	0.947984536	-0.198612096	normal	0.055011715	0.760156113	normal	0.959067922	-0.155824159	normal	0.841951529	0.128279827	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Phosphatidylinositol transfer protein	Cytoplasmic phosphatidylinositol transfer protein 1 GN=PITPNC1 OS=Homo sapiens (Human) PE=1 SV=3	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: cytoplasmic phosphatidylinositol transfer protein 1 isoform X1 [Tupaia chinensis]
ENSG00000154222(CC2D1B)	--	9.264480917	846	10.187648	934	8.444427201	788	9.900860367	902	10.02797017	886	11.5597466	1054	0.976457202	0.061529281	normal	0.974070266	-0.097380494	normal	0.686363494	0.410632187	normal	0.584775034	0.125283836	normal	--	--	--	K18260|0|hsa:200014|CC2D1B; coiled-coil and C2 domain containing 1B; K18260 coiled-coil and C2 domain-containing protein 1 (A)	--	[R]	General function prediction only	C2 domain	Coiled-coil and C2 domain-containing protein 1B GN=CC2D1B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: coiled-coil and C2 domain-containing protein 1B [Ceratotherium simum simum]
ENSG00000154229(PRKCA)	--	32.0278	5650	28.4795	5006	30.80539	5364	26.5737	4674	24.42212	4277	19.78424	3496	0.957247564	-0.30433424	normal	0.975400139	-0.248404358	normal	0.040603685	-0.625675278	normal	0.015004615	-0.386068029	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K02677|0|hsa:5578|PRKCA, AAG6, PKC-alpha, PKCA, PRKACA; protein kinase C, alpha (EC:2.7.11.13); K02677 classical protein kinase C [EC:2.7.11.13] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; HIF-1 signaling pathway (ko04066);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Tight junction (ko04530);; Gap junction (ko04540);; Natural killer cell mediated cytotoxicity (ko04650);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Vibrio cholerae infection (ko05110);; Pathogenic Escherichia coli infection (ko05130);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2 domain;; Protein kinase C terminal domain	Protein kinase C alpha type GN=PRKCA OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: protein kinase C alpha type [Tupaia chinensis]
ENSG00000154237(LRRK1)	--	10.48891989	1669	10.40690996	1647	10.30310211	1682	9.771236863	1488	9.910123083	1593	9.549703188	1518	0.967933579	-0.196250214	normal	0.983004507	-0.069455994	normal	0.975696751	-0.156149502	normal	0.491182459	-0.141097709	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: GTP binding (GO:0005525);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K08843|0|hsa:79705|LRRK1, RIPK6, Roco1; leucine-rich repeat kinase 1 (EC:2.7.11.1); K08843 leucine-rich repeat kinase 1 [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Miro-like protein;; Ankyrin repeat;; ADP-ribosylation factor family;; Leucine rich repeat;; Ras family;; Ankyrin repeats (many copies)	Leucine-rich repeat serine/threonine-protein kinase 1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat serine/threonine-protein kinase 1 isoform X1 [Equus caballus]
ENSG00000154240(CEP112)	--	5.658159709	473	5.606017541	468	5.304886655	433	4.3795219	366	4.645597055	400	4.37293782	372	0.743769407	-0.399349453	normal	0.927580166	-0.247070475	normal	0.937167611	-0.226501498	normal	0.206510342	-0.293121246	normal	--	--	--	"K16767|0|ptr:468302|CEP112, CCDC46; centrosomal protein 112kDa; K16767 centrosomal protein CEP112 (A)"	--	--	--	Domain of unknown function (DUF4485)	Centrosomal protein of 112 kDa GN=CEP112 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 112 kDa isoform X2 [Tupaia chinensis]
ENSG00000154252(GAL3ST2)	--	1.108309682	40	1.421582	47	1.307314211	49	0.24627111	9	0.311502	7	0.87083035	32	0.007651384	-2.007001692	down	4.89E-05	-2.529921583	down	0.923958967	-0.599924445	normal	0.004081985	-1.519533258	down	--	--	Molecular Function: galactosylceramide sulfotransferase activity (GO:0001733);; Cellular Component: Golgi apparatus (GO:0005794);; Biological Process: glycolipid biosynthetic process (GO:0009247);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09675|0|hsa:64090|GAL3ST2, GAL3ST-2, GP3ST; galactose-3-O-sulfotransferase 2; K09675 galactose-3-O-sulfotransferase 2 [EC:2.8.2.-] (A)"	--	--	--	Galactose-3-O-sulfotransferase	Galactose-3-O-sulfotransferase 2 GN=GAL3ST2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	galactose-3-O-sulfotransferase 2 [Sus scrofa] 
ENSG00000154258(ABCA9)	--	0.009075032	1	0.017969334	2	0	0	0.018049727	2	0.017698168	1	0.027080838	3	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05651|0|hsa:10350|ABCA9, EST640918; ATP-binding cassette, sub-family A (ABC1), member 9; K05651 ATP-binding cassette, subfamily A (ABC1), member 9 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	"ABC transporter;; ABC-2 family transporter protein;; AAA domain;; Protein of unknown function, DUF258;; P-loop containing region of AAA domain"	ATP-binding cassette sub-family A member 9 GN=ABCA9 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family A member 9 isoformX2 [Canis lupus familiaris]
ENSG00000154262(ABCA6)	--	0.0847689	3	0.0107647	1	0	0	0.0762754	2	0.0104404	0	0.0597787	3	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05649|0|hsa:23460|ABCA6, EST155051; ATP-binding cassette, sub-family A (ABC1), member 6; K05649 ATP-binding cassette, subfamily A (ABC1), member 6 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	"ABC transporter;; ABC-2 family transporter protein;; AAA domain;; Protein of unknown function, DUF258"	ATP-binding cassette sub-family A member 6 GN=ABCA6 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 6 [Galeopterus variegatus]
ENSG00000154263(ABCA10)	--	4.803070526	379	3.916355023	337	4.67607703	335	4.223080908	370	4.914954239	308	7.972681403	577	0.967258967	-0.065237163	normal	0.955946081	-0.15053787	normal	0.003671064	0.773426442	normal	0.686778393	0.235962241	normal	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05652|0|hsa:10349|ABCA10, EST698739; ATP-binding cassette, sub-family A (ABC1), member 10; K05652 ATP-binding cassette, subfamily A (ABC1), member 10 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	"ABC transporter;; ABC-2 family transporter protein;; AAA domain;; Protein of unknown function, DUF258;; AAA domain;; P-loop containing region of AAA domain"	ATP-binding cassette sub-family A member 10 GN=ABCA10 OS=Homo sapiens (Human) PE=2 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family A member 10 [Equus przewalskii]
ENSG00000154269(ENPP3)	--	0.019096548	1	0.073404384	4	0	0	0.019178662	1	0.01860662	0	0.019071229	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: immune response (GO:0006955);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: polysaccharide binding (GO:0030247);; Molecular Function: metal ion binding (GO:0046872);; 	"K01513|0|hsa:5169|ENPP3, B10, CD203c, NPP3, PD-IBETA, PDNP3; ectonucleotide pyrophosphatase/phosphodiesterase 3 (EC:3.1.4.1 3.6.1.9); K01513 ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] (A)"	Purine metabolism (ko00230);; Starch and sucrose metabolism (ko00500);; Riboflavin metabolism (ko00740);; Nicotinate and nicotinamide metabolism (ko00760);; Pantothenate and CoA biosynthesis (ko00770)	[R]	General function prediction only	Type I phosphodiesterase / nucleotide pyrophosphatase;; Somatomedin B domain;; DNA/RNA non-specific endonuclease	Nucleotide pyrophosphatase GN=ENPP3 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: ectonucleotide pyrophosphatase/phosphodiesterase family member 3 [Odobenus rosmarus divergens]
ENSG00000154274(C4orf19)	--	0	0	0	0	0	0	0.126949343	5	0.074753262	2	0.152142	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C4orf19 GN=C4orf19 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C4orf19 homolog isoform X1 [Tupaia chinensis] 
ENSG00000154277(UCHL1)	--	472.0415882	8895	468.5555177	9056	437.5603907	8338	461.2790842	8841	434.1931243	8145	450.2767815	8433	0.995746377	-0.039610445	normal	0.991810696	-0.174355098	normal	0.995651036	0.008051688	normal	0.792657495	-0.070046644	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Cellular Component: intracellular (GO:0005622);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; 	K05611|1.56293e-129|ptr:461185|UCHL1; ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase); K05611 ubiquitin carboxyl-terminal hydrolase L1 [EC:3.4.19.12] (A)	Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ubiquitin carboxyl-terminal hydrolase, family 1"	Ubiquitin carboxyl-terminal hydrolase isozyme L1 (Precursor) GN=UCHL1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase isozyme L1 isoform X1 [Mustela putorius furo] 
ENSG00000154305(MIA3)	--	11.56940731	1170	9.662706084	1029	11.08872271	1056	12.96536015	1366	13.7199659	1479	11.48174281	1222	0.964765631	0.192382714	normal	0.350943356	0.501334863	normal	0.960295399	0.202073774	normal	0.074854729	0.29982174	normal	--	--	--	--	--	--	--	Variant SH3 domain	Melanoma inhibitory activity protein 3 (Precursor) GN=UNQ6077/PRO20088 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: melanoma inhibitory activity protein 3 [Trichechus manatus latirostris]
ENSG00000154309(DISP1)	--	5.608835489	137	9.246789334	140	6.238568128	137	5.780851701	160	7.321573001	146	7.597816652	144	0.954718569	0.191079422	normal	0.966359704	0.038705564	normal	0.967000034	0.062923926	normal	0.850199793	0.098739778	normal	--	--	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[T]	Signal transduction mechanisms	Patched family;; MMPL family;; Sterol-sensing domain of SREBP cleavage-activation	Protein dispatched homolog 1 GN=DISP1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: protein dispatched homolog 1 isoform X1 [Tupaia chinensis] 
ENSG00000154310(TNIK)	--	1.891761507	273	1.603963887	237	2.780173036	288	3.00815074	368	2.960257117	266	2.030271105	269	0.772630922	0.398037035	normal	0.956546502	0.144243498	normal	0.962535114	-0.106177063	normal	0.632997494	0.156310924	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08840|0|ptr:460849|TNIK; TRAF2 and NCK interacting kinase; K08840 TRAF2 and NCK interacting kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; CNH domain;; Protein tyrosine kinase	TRAF2 and NCK-interacting protein kinase GN=TNIK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TRAF2 and NCK-interacting protein kinase isoform X3 [Oryctolagus cuniculus]
ENSG00000154319(FAM167A)	--	1.514814886	125	1.173365646	97	0.919856523	64	3.306253321	271	4.888081308	400	4.268986798	341	0.000104412	1.076337824	up	0	2.005846782	up	0	2.378140861	up	2.18E-08	1.801889789	up	--	--	--	--	--	--	--	Protein of unknown function (DUF3259)	Protein FAM167A GN=FAM167A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM167A [Tupaia chinensis] 
ENSG00000154328(NEIL2)	--	12.52534	495	9.090774944	377	12.002968	491	10.15608976	407	9.365936277	365	6.84728406	266	0.880051944	-0.312161392	normal	0.966200007	-0.067818119	normal	0.000389197	-0.888809832	normal	0.139025083	-0.415097185	normal	[L]	"Replication, recombination and repair"	"Molecular Function: damaged DNA binding (GO:0003684);; Molecular Function: DNA-(apurinic or apyrimidinic site) lyase activity (GO:0003906);; Biological Process: nucleotide-excision repair (GO:0006289);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, hydrolyzing N-glycosyl compounds (GO:0016799);; "	"K10568|0|hsa:252969|NEIL2, NEH2, NEI2; nei endonuclease VIII-like 2 (E. coli) (EC:4.2.99.18); K10568 endonuclease VIII-like 2 [EC:3.2.2.- 4.2.99.18] (A)"	Base excision repair (ko03410)	--	--	Formamidopyrimidine-DNA glycosylase H2TH domain;; Formamidopyrimidine-DNA glycosylase N-terminal domain	Endonuclease 8-like 2 GN=NEIL2 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: endonuclease 8-like 2 isoform X1 [Equus caballus] 
ENSG00000154330(PGM5)	--	1.255916613	67	2.1999227	129	1.505764	77	0.502097819	30	0.762145063	38	1.82559476	94	0.115552131	-1.14958623	normal	3.94E-07	-1.744704739	down	0.953919694	0.274621936	normal	0.384792933	-0.771251422	normal	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: intramolecular transferase activity, phosphotransferases (GO:0016868);; "	"K15636|0|hsa:5239|PGM5, PGMRP; phosphoglucomutase 5; K15636 phosphoglucomutase-like protein 5 (A)"	--	[G]	Carbohydrate transport and metabolism	"Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II"	Phosphoglucomutase-like protein 5 GN=PGM5 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: phosphoglucomutase-like protein 5 [Orcinus orca]
ENSG00000154342(WNT3A)	--	0.0411189	2	0.0200076	1	0.0195103	0	0.0409642	2	0	0	0.0201881	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00312|0|nle:100606846|WNT3A; wingless-type MMTV integration site family, member 3A; K00312 wingless-type MMTV integration site family, member 3 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-3a (Precursor) GN=WNT3A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-3a [Tupaia chinensis] 
ENSG00000154358(OBSCN)	--	4.27447536	1311	4.055279488	1216	4.123286173	1155	1.976955867	560	2.5789638	786	2.685588514	890	5.14E-11	-1.255677904	down	0.025983791	-0.64995467	normal	0.765283588	-0.383732995	normal	6.96E-05	-0.739503052	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K17531|0|pps:100978824|OBSCN; obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; K17531 Obscurin-RhoGEF [EC:2.7.11.1] (A)"	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Protein kinase domain;; Protein tyrosine kinase;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain;; Fibronectin type III domain;; RhoGEF domain;; Penicillin-Binding Protein C-terminus Family;; IQ calmodulin-binding motif	Obscurin GN=OBSCN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: obscurin [Orycteropus afer afer]
ENSG00000154359(LONRF1)	--	5.621499369	323	5.405685595	307	4.984082037	284	5.405423498	320	5.49236378	317	7.502023033	356	0.967323802	-0.044083844	normal	0.966817239	0.024697901	normal	0.884076474	0.316188044	normal	0.782633671	0.098544638	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATP-dependent protease La (LON) domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc finger of C3HC4-type, RING;; TPR repeat;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; U-box domain"	LON peptidase N-terminal domain and RING finger protein 1 GN=LONRF1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LON peptidase N-terminal domain and RING finger protein 1 [Odobenus rosmarus divergens]
ENSG00000154370(TRIM11)	--	13.69307581	830	15.878107	981	14.15944271	883	14.1842	850	15.45445236	955	16.00186439	969	0.977509026	0.003512816	normal	0.977324069	-0.060085079	normal	0.971877599	0.1255864	normal	0.951807697	0.021370898	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K10650|0|pps:100973897|TRIM11; tripartite motif containing 11; K10650 tripartite motif-containing protein 11 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY-associated domain;; SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; RING-type zinc-finger;; B-box zinc finger"	E3 ubiquitin-protein ligase TRIM11 GN=TRIM11 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM11 isoform X1 [Tupaia chinensis]
ENSG00000154380(ENAH)	--	42.43354165	4240	39.72438729	4071	44.46992606	4470	48.87898549	5208	52.18191645	5113	33.75337045	3301	0.970704581	0.265745911	normal	0.953151373	0.30725821	normal	0.673763715	-0.445487053	normal	0.873172277	0.069704034	normal	--	--	--	K05746|0|ggo:101129354|uncharacterized protein LOC101129354; K05746 enabled (A)	Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	WH1 domain;; VASP tetramerisation domain	Protein enabled homolog GN=ENAH OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein enabled homolog [Vicugna pacos]
ENSG00000154429(CCSAP)	--	3.64008078	281	4.55326323	350	4.36337	332	3.959261066	309	4.381620001	339	4.4640244	344	0.962664487	0.105653446	normal	0.965698563	-0.06720115	normal	0.967762084	0.042742605	normal	0.965782714	0.022008819	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; 	"K16454|6.43417e-136|hsa:126731|CCSAP, C1orf96, CSAP; centriole, cilia and spindle-associated protein; K16454 centriole, cilia and spindle-associated protein (A)"	--	--	--	--	"Centriole, cilia and spindle-associated protein GN=CCSAP OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: centriole, cilia and spindle-associated protein [Felis catus] "
ENSG00000154438(ASZ1)	--	0	0	0	0	0	0	0	0	0.069469356	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K18410|0|ptr:450111|ASZ1, GASZ; ankyrin repeat, SAM and basic leucine zipper domain containing 1; K18410 ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	"Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 OS=Homo sapiens (Human) PE=2 SV=1"	R	General function prediction only	"PREDICTED: ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1 [Ursus maritimus]"
ENSG00000154447(SH3RF1)	--	7.00496	693	7.428081431	733	7.838366401	768	11.16764624	1098	10.5319447	1034	10.4203632	1030	0.035005538	0.631996474	normal	0.465887003	0.474097286	normal	0.673791382	0.414467521	normal	0.001372815	0.506001074	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	K12171|0|pps:100989963|SH3RF1; SH3 domain containing ring finger 1; K12171 E3 ubiquitin-protein ligase SH3RF [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain;; RING-type zinc-finger;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase SH3RF1 GN=SH3RF1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase SH3RF1 [Ceratotherium simum simum]
ENSG00000154451(GBP5)	--	0	0	0	0	0	0	0	0	0.049778105	1	0.101064143	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	"Guanylate-binding protein, N-terminal domain;; Guanylate-binding protein, C-terminal domain"	Guanylate-binding protein 5 (Precursor) GN=GBP5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: guanylate-binding protein 5-like [Ceratotherium simum simum]
ENSG00000154473(BUB3)	--	79.731849	2677	77.98265711	2518	79.98513247	2546	79.881933	2621	76.3999245	2537	72.33309909	2267	0.988450253	-0.061296493	normal	0.988571071	-0.010574994	normal	0.978813987	-0.175628848	normal	0.726846246	-0.081754669	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K02180|0|umr:103657966|BUB3; BUB3 mitotic checkpoint protein; K02180 cell cycle arrest protein BUB3 (A)	Cell cycle (ko04110);; HTLV-I infection (ko05166)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"WD domain, G-beta repeat"	Mitotic checkpoint protein BUB3 GN=BUB3 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: mitotic checkpoint protein BUB3 isoform 1 [Ceratotherium simum simum]
ENSG00000154479(CCDC173)	--	0.08474266	3	0.056195996	3	0.056178107	2	0.041837739	2	0.020408974	0	0.129764298	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Tumour suppressor, Mitostatin"	Coiled-coil domain-containing protein 173 GN=CCDC173 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 173 [Pantholops hodgsonii]
ENSG00000154485(MMP21)	--	0.0318319	1	0	0	0.0306635	0	0	0	0	0	0.031218	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K08000|0|hsa:118856|MMP21, MMP-21; matrix metallopeptidase 21; K08000 matrix metalloproteinase-21 [EC:3.4.24.-] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	Matrix metalloproteinase-21 (Precursor) GN=MMP21 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: matrix metalloproteinase-21 [Tupaia chinensis] 
ENSG00000154493(C10orf90)	--	0.208679244	6	0.105414231	3	0.034735339	0	0.105272827	4	0.134722187	3	0.052637548	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16773|0|hsa:118611|C10orf90, FATS, bA422P15.2; chromosome 10 open reading frame 90; K16773 fragile-site associated tumor suppressor (A)"	--	--	--	ALMS motif	Centrosomal protein C10orf90 GN=C10orf90 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: centrosomal protein C10orf90 homolog isoform X1 [Equus caballus]
ENSG00000154511(FAM69A)	--	13.53734904	540	12.04597319	450	12.82456571	513	11.99047563	466	10.53447181	413	9.073341351	355	0.930794417	-0.242717455	normal	0.958863825	-0.144701971	normal	0.289594739	-0.5375154	normal	0.167520969	-0.306406934	normal	--	--	--	--	--	--	--	"Protein-kinase domain of FAM69;; N-term cysteine-rich ER, FAM69"	Protein FAM69A GN=FAM69A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM69A isoform X1 [Chrysochloris asiatica] 
ENSG00000154518(ATP5G3)	--	196.27818	2788	185.21053	2691	193.03064	2921	180.29483	2483	148.35946	2083	129.89601	1902	0.976527528	-0.197862933	normal	0.809490908	-0.39065582	normal	0.032447175	-0.626831211	normal	0.008562092	-0.398979869	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting two-sector ATPase complex, proton-transporting domain (GO:0033177);; "	"K02128|4.18884e-79|rno:114630|Atp5g3; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9); K02128 F-type H+-transporting ATPase subunit c (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	ATP synthase subunit C	"ATP synthase F(0) complex subunit C3, mitochondrial (Precursor) GN=ATP5G3 OS=Homo sapiens (Human) PE=2 SV=1"	C	Energy production and conversion	"PREDICTED: ATP synthase lipid-binding protein, mitochondrial-like [Condylura cristata]"
ENSG00000154529(CNTNAP3B)	--	26.86178205	2426	24.61187304	2337	24.02589932	2136	12.91262171	1145	13.27081249	1273	13.24876541	1318	3.42E-09	-1.113012566	down	1.86E-05	-0.897052644	normal	0.004512695	-0.704211685	normal	1.93E-11	-0.905819301	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; F5/8 type C domain;; Concanavalin A-like lectin/glucanases superfamily	Contactin-associated protein-like 3B (Precursor) GN=CNTNAP3B OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: contactin-associated protein-like 3-like [Odobenus rosmarus divergens]
ENSG00000154545(MAGED4)	--	0.0171851	1	0.018180747	1	0	0	0.0171291	1	0.0357238	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MAGE family	Melanoma-associated antigen D4 GN=MAGED4B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: melanoma-associated antigen D4 [Galeopterus variegatus]
ENSG00000154548(SRSF12)	--	0.492194259	26	0.666850647	35	0.71802687	37	0.962570979	53	1.01430325	55	0.881004	49	0.616507627	0.956339831	normal	0.902215106	0.609486383	normal	0.964184215	0.383311023	normal	0.242199964	0.658829121	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Serine/arginine-rich splicing factor 12 GN=SRSF12 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 12 [Oryctolagus cuniculus]
ENSG00000154553(PDLIM3)	--	0	0	0	0	0.063610665	1	0.080987026	3	0.128265975	3	0.065177937	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	PDZ domain (Also known as DHR or GLGF);; LIM domain	PDZ and LIM domain protein 3 GN=PDLIM3 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: PDZ and LIM domain protein 3 isoform X2 [Mustela putorius furo] 
ENSG00000154556(SORBS2)	--	0.49590693	7	0.640192838	6	0.044307041	2	0.565787746	5	0.442381211	11	1.044770179	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	SH3 domain;; Variant SH3 domain;; Sorbin homologous domain;; Variant SH3 domain	Sorbin and SH3 domain-containing protein 2 GN=SORBS2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: sorbin and SH3 domain-containing protein 2 isoform X1 [Ursus maritimus]
ENSG00000154582(ELOC)	--	68.3601344	1044	68.1138369	1057	61.1876556	923	83.4002325	1246	67.65800573	982	67.6744899	1014	0.952986232	0.224047979	normal	0.97252872	-0.127417814	normal	0.972308779	0.12716481	normal	0.750743297	0.078288019	normal	--	--	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; 	"K03872|2.24123e-78|xtr:549174|tceb1; transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C); K03872 transcription elongation factor B, polypeptide 1 (A)"	Ubiquitin mediated proteolysis (ko04120)	[K]	Transcription	"Skp1 family, tetramerisation domain"	Transcription elongation factor B polypeptide 1 GN=TCEB1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription elongation factor B polypeptide 1 isoform X3 [Physeter catodon]
ENSG00000154589(LY96)	--	0.196816	1	0	0	0.774784	3	1.882832041	10	1.33964	6	1.193147	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05400|1.96486e-90|ptr:746178|LY96, MD2; lymphocyte antigen 96; K05400 lymphocyte antigen 96 (A)"	NF-kappa B signaling pathway (ko04064);; Toll-like receptor signaling pathway (ko04620);; Pertussis (ko05133);; Toxoplasmosis (ko05145)	--	--	ML domain	Lymphocyte antigen 96 (Precursor) GN=LY96 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lymphocyte antigen 96 isoform 1 [Dasypus novemcinctus]
ENSG00000154620(TMSB4Y)	--	1.464515392	37	1.961753242	43	1.318103953	33	0.311737374	8	0.647923121	16	0.6310814	16	0.011757529	-2.042432002	normal	0.207593174	-1.365973663	normal	0.851104452	-0.986494319	normal	0.007405051	-1.517820141	down	--	--	--	"K05764|2.87422e-22|hsa:9087|TMSB4Y, TB4Y; thymosin beta 4, Y-linked; K05764 thymosin, beta 4 (A)"	Regulation of actin cytoskeleton (ko04810)	[N]	Cell motility	--	"Thymosin beta-4, Y-chromosomal GN=TMSB4Y OS=Homo sapiens (Human) PE=2 SV=3"	N	Cell motility	"PREDICTED: thymosin beta-4, Y-chromosomal-like [Odobenus rosmarus divergens]"
ENSG00000154639(CXADR)	--	6.927546524	497	5.950261	504	5.692278195	433	5.854726221	486	6.4560019	445	6.699799159	490	0.969774828	-0.062925075	normal	0.946718943	-0.200404507	normal	0.955407824	0.16956625	normal	0.926324851	-0.034598185	normal	--	--	--	"K06788|0|pon:100174624|CXADR, CAR; coxsackie virus and adenovirus receptor; K06788 coxsackievirus and adenovirus receptor (A)"	Viral myocarditis (ko05416)	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD47 immunoglobulin-like domain	Coxsackievirus and adenovirus receptor (Precursor) GN=CXADR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: coxsackievirus and adenovirus receptor isoform X1 [Equus przewalskii]
ENSG00000154640(BTG3)	--	19.75596241	464	18.50183971	443	20.545422	483	16.628072	398	16.11022021	372	11.991872	285	0.925631453	-0.251289091	normal	0.913267092	-0.272414329	normal	0.006404797	-0.766192859	normal	0.048721093	-0.419841955	normal	--	--	--	"K14443|0|hsa:10950|BTG3, ANA, TOB5, TOB55, TOFA; BTG family, member 3; K14443 protein Tob/BTG (A)"	RNA degradation (ko03018)	[TR]	Signal transduction mechanisms;; General function prediction only	BTG family	Protein BTG3 GN=BTG3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	hypothetical protein PANDA_002392 [Ailuropoda melanoleuca]
ENSG00000154642(C21orf91)	--	1.530984202	101	2.069924544	121	1.258549346	87	0.721835543	54	0.946165531	66	0.831754748	62	0.14852366	-0.914804456	normal	0.110294594	-0.880758774	normal	0.891294726	-0.486963907	normal	0.047625845	-0.784842154	normal	--	--	--	--	--	--	--	EURL protein	Protein EURL homolog GN=EURL OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein EURL homolog isoform X1 [Equus przewalskii]
ENSG00000154646(TMPRSS15)	--	0.015381386	1	0	0	0	0	0.045830726	3	0.02987429	1	0.112341009	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: scavenger receptor activity (GO:0005044);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K01316|0|hsa:5651|TMPRSS15, ENTK, PRSS7; transmembrane protease, serine 15 (EC:3.4.21.9); K01316 protease, serine, 7 (enterokinase) [EC:3.4.21.9] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; CUB domain;; MAM domain;; SEA domain;; Low-density lipoprotein receptor domain class A;; Domain of unknown function (DUF1986);; Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	Enteropeptidase catalytic light chain (Precursor) GN=TMPRSS15 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: enteropeptidase isoform 2 [Equus caballus]
ENSG00000154654(NCAM2)	--	0	0	0	0	0	0	0.011299952	1	0.011012094	0	0.011304944	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06491|0|hsa:4685|NCAM2, NCAM21; neural cell adhesion molecule 2; K06491 neural cell adhesion molecule (A)"	Cell adhesion molecules (CAMs) (ko04514);; Prion diseases (ko05020)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Fibronectin type III domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Neural cell adhesion molecule 2 (Precursor) GN=NCAM2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neural cell adhesion molecule 2-like [Mustela putorius furo] 
ENSG00000154655(L3MBTL4)	--	0.184733082	1	0	0	0	0	0.030541903	2	0.059519967	3	0.091220556	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	--	--	[K]	Transcription	"mbt repeat;; SAM domain (Sterile alpha motif);; Zinc finger, C2HC type;; SAM domain (Sterile alpha motif)"	Lethal(3)malignant brain tumor-like protein 4 GN=L3MBTL4 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: lethal(3)malignant brain tumor-like protein 4 isoform X5 [Mustela putorius furo] 
ENSG00000154678(PDE1C)	--	0.457291147	52	0.294818097	42	0.817439744	72	2.5570596	299	2.3575355	283	1.4060222	169	0	2.458634967	up	0	2.687998889	up	0.000210707	1.205648988	up	3.52E-06	2.155801728	up	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13755|0|bta:526211|PDE1C; phosphodiesterase 1C, calmodulin-dependent 70kDa; K13755 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17] (A)"	Purine metabolism (ko00230);; Calcium signaling pathway (ko04020);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; 3'5'-cyclic nucleotide phosphodiesterase N-terminal	"Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C GN=PDE1C OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C isoform X1 [Condylura cristata]"
ENSG00000154710(RABGEF1)	--	8.969048115	685	11.0004989	736	9.507391179	629	11.5954062	850	11.8013629	833	9.600482465	754	0.91297129	0.279962007	normal	0.964111314	0.156881029	normal	0.929666179	0.252657532	normal	0.258180176	0.227726538	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar sorting protein 9 (VPS9) domain;; A20-like zinc finger	Rab5 GDP/GTP exchange factor GN=RABGEF1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab5 GDP/GTP exchange factor isoform X3 [Sus scrofa]
ENSG00000154719(MRPL39)	--	17.43515308	283	17.90323904	292	18.16155764	292	20.19425578	334	17.6840005	282	17.06995588	278	0.943695433	0.207177567	normal	0.964417304	-0.071323852	normal	0.964954513	-0.078756846	normal	0.964587023	0.022465192	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K17420|0|hsa:54148|MRPL39, C21orf92, L39mt, MRP-L5, MRPL5, PRED22, PRED66, RPML5; mitochondrial ribosomal protein L39; K17420 large subunit ribosomal protein L39 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	--	"39S ribosomal protein L39, mitochondrial OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L39, mitochondrial [Galeopterus variegatus]"
ENSG00000154721(JAM2)	--	0.096116074	7	0.131205472	5	0.054714138	3	0.027405667	2	0.066370775	4	0.027129126	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06735|0|hsa:58494|JAM2, C21orf43, CD322, JAM-B, JAMB, PRO245, VE-JAM, VEJAM; junctional adhesion molecule 2; K06735 junctional adhesion molecule 2 (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Epithelial cell signaling in Helicobacter pylori infection (ko05120)	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Junctional adhesion molecule B (Precursor) GN=JAM2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: junctional adhesion molecule B [Ursus maritimus]
ENSG00000154723(ATP5J)	--	100.0346925	717	109.392345	832	113.446986	850	112.275681	864	110.102471	786	108.924648	802	0.939479619	0.237761288	normal	0.971956462	-0.103287581	normal	0.973827823	-0.091983539	normal	0.980122653	0.010219616	normal	--	--	"Cellular Component: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) (GO:0000276);; Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP synthesis coupled proton transport (GO:0015986);; "	"K02131|1.11865e-63|hsa:522|ATP5J, ATP5, ATP5A, ATPM, CF6, F6; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 (EC:3.6.1.14); K02131 F-type H+-transporting ATPase subunit 6 (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Mitochondrial ATP synthase coupling factor 6	"ATP synthase-coupling factor 6, mitochondrial (Precursor) GN=ATP5J OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: ATP synthase-coupling factor 6, mitochondrial isoform X1 [Tupaia chinensis] "
ENSG00000154727(GABPA)	--	7.05495	525	6.319944	462	6.475922	468	6.783418	507	7.863235	581	6.846426	504	0.969045862	-0.080922922	normal	0.88459643	0.308317104	normal	0.96700969	0.098317559	normal	0.704654063	0.108623321	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09441|0|ptr:474079|GABPA; GA binding protein transcription factor, alpha subunit 60kDa; K09441 GA-binding protein transcription factor, alpha (A)"	--	[K]	Transcription	GA-binding protein alpha chain;; Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	GA-binding protein alpha chain GN=GABPA OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: GA-binding protein alpha chain [Orycteropus afer afer]
ENSG00000154734(ADAMTS1)	--	0.050951652	5	0.06413796	6	0.10457416	7	0.026291766	2	0.02572772	1	0.013159455	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08617|0|hsa:9510|ADAMTS1, C3-C5, METH1; ADAM metallopeptidase with thrombospondin type 1 motif, 1; K08617 a disintegrin and metalloproteinase with thrombospondin motifs 1 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease;; Thrombospondin type 1 domain;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 1 (Precursor) GN=ADAMTS1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: A disintegrin and metalloproteinase with thrombospondin motifs 1 [Vicugna pacos]
ENSG00000154743(TSEN2)	--	10.50517812	336	12.72555781	345	12.33466495	373	12.13963375	385	11.30167791	327	11.28156145	338	0.954572112	0.16486033	normal	0.963080801	-0.098289663	normal	0.95752826	-0.149805499	normal	0.954960941	-0.026969374	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: tRNA-intron endonuclease activity (GO:0000213);; Biological Process: tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388);; "	"K15322|0|hsa:80746|TSEN2, PCH2B, SEN2, SEN2L; TSEN2 tRNA splicing endonuclease subunit (EC:4.6.1.16); K15322 tRNA-splicing endonuclease subunit Sen2 [EC:3.1.27.9] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA intron endonuclease, catalytic C-terminal domain;; tRNA intron endonuclease, N-terminal domain"	tRNA-splicing endonuclease subunit Sen2 GN=TSEN2 OS=Homo sapiens (Human) PE=2 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-splicing endonuclease subunit Sen2 isoform X1 [Galeopterus variegatus]
ENSG00000154760(SLFN13)	--	6.520308476	557	7.179642904	578	9.855139557	601	7.4720157	513	7.33142369	506	5.513540739	412	0.960909783	-0.149121969	normal	0.944030828	-0.212763176	normal	0.218753613	-0.551326338	normal	0.154277352	-0.30043357	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	Divergent AAA domain;; Uncharacterized conserved protein (DUF2075)	Schlafen family member 13 GN=SLFN13 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: schlafen family member 11 isoform X1 [Equus caballus] 
ENSG00000154764(WNT7A)	--	0	0	0	0	0	0	0.134058	10	0.091677	6	0.013373	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00572|0|pps:100995012|WNT7A; wingless-type MMTV integration site family, member 7A; K00572 wingless-type MMTV integration site family, member 7 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-7a (Precursor) GN=WNT7A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-7a [Ailuropoda melanoleuca] 
ENSG00000154767(XPC)	--	17.764536	1653	17.81976675	1687	19.16433438	1807	16.506797	1537	15.74893085	1450	18.302854	1701	0.978224326	-0.135671003	normal	0.954561473	-0.239601694	normal	0.982888637	-0.095422482	normal	0.429830998	-0.155538206	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; 	"K10838|0|hsa:7508|XPC, RAD4, XP3, XPCC, p125; xeroderma pigmentosum, complementation group C; K10838 xeroderma pigmentosum group C-complementing protein (A)"	Nucleotide excision repair (ko03420)	[L]	"Replication, recombination and repair"	Rad4 transglutaminase-like domain;; Rad4 beta-hairpin domain 3;; Rad4 beta-hairpin domain 2;; Rad4 beta-hairpin domain 1	DNA repair protein complementing XP-C cells GN=XPC OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein complementing XP-C cells [Galeopterus variegatus]
ENSG00000154783(FGD5)	--	0.007602129	1	0	0	0	0	0	0	0.014758698	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Molecular Function: metal ion binding (GO:0046872);; 	"K05724|0|hsa:152273|FGD5, ZFYVE23; FYVE, RhoGEF and PH domain containing 5; K05724 FYVE, RhoGEF and PH domain containing 5/6 (A)"	--	[R]	General function prediction only	RhoGEF domain;; PH domain;; FYVE zinc finger	"FYVE, RhoGEF and PH domain-containing protein 5 GN=FGD5 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: FYVE, RhoGEF and PH domain-containing protein 5 [Myotis brandtii]"
ENSG00000154803(FLCN)	--	15.82744	981	21.47365	1266	17.30179	974	13.77533	805	15.077697	926	26.41066	1627	0.882015895	-0.315549975	normal	0.472196965	-0.471957741	normal	0.00248618	0.731041489	normal	0.968742065	0.04071751	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; 	K09594|0|ggo:101136366|FLCN; folliculin; K09594 folliculin (A)	Renal cell carcinoma (ko05211)	[UE]	"Intracellular trafficking, secretion, and vesicular transport;; Amino acid transport and metabolism"	Vesicle coat protein involved in Golgi to plasma membrane transport	Folliculin GN=FLCN OS=Homo sapiens (Human) PE=1 SV=1	EU	"Amino acid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: folliculin [Condylura cristata]
ENSG00000154813(DPH3)	--	14.09944	735	12.34928	639	13.72693	696	14.90951	776	13.42552	696	12.94537	674	0.975343217	0.047383739	normal	0.969592047	0.101614348	normal	0.973981734	-0.054509792	normal	0.925899693	0.030431346	normal	[S]	Function unknown	--	K15455|4.80631e-53|pps:100979998|DPH3; diphthamide biosynthesis 3; K15455 diphthamide biosynthesis protein 3 (A)	--	[S]	Function unknown	CSL zinc finger	DPH3 homolog GN=DPH3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DPH3 homolog isoform 1 [Dasypus novemcinctus]
ENSG00000154814(OXNAD1)	--	5.315735717	230	5.837038805	246	6.935246467	287	6.4868308	271	5.299974001	239	6.521864316	275	0.945494024	0.20456678	normal	0.964402097	-0.062683286	normal	0.965514188	-0.06953621	normal	0.972555047	0.020138689	normal	[C]	Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Oxidoreductase NAD-binding domain;; Ferric reductase NAD binding domain	Oxidoreductase NAD-binding domain-containing protein 1 (Precursor) GN=OXNAD1 OS=Homo sapiens (Human) PE=1 SV=1	CH	Energy production and conversion;; Coenzyme transport and metabolism	PREDICTED: oxidoreductase NAD-binding domain-containing protein 1 isoform 2 [Trichechus manatus latirostris]
ENSG00000154822(PLCL2)	--	2.027930359	175	2.222988769	171	2.441086582	199	3.920649137	322	2.96604278	241	3.501260732	293	0.004877999	0.843337173	normal	0.698847711	0.47009288	normal	0.42011865	0.546398289	normal	0.010752151	0.630004163	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	K15370|0|ptr:470763|PLCL2; phospholipase C-like 2; K15370 inactive phospholipase C-like protein 2 (A)	--	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain"	Inactive phospholipase C-like protein 2 GN=PLCL2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: phospholipase C-like 2 isoformX1 [Canis lupus familiaris]
ENSG00000154832(CXXC1)	--	13.96013	554	11.80306003	584	14.15863502	579	13.51187094	606	12.76440341	566	12.975989	580	0.96877979	0.098338747	normal	0.970606106	-0.066418157	normal	0.973367133	-0.005786789	normal	0.986194426	0.007789381	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	K14960|0|ptr:455419|CXXC1; CXXC finger protein 1; K14960 COMPASS component SPP1 (A)	--	[R]	General function prediction only	CpG binding protein zinc finger C terminal domain;; CXXC zinc finger domain;; PHD-finger	CXXC-type zinc finger protein 1 GN=CXXC1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cpG-binding protein isoform X1 [Leptonychotes weddellii]
ENSG00000154839(SKA1)	--	7.969133618	366	10.5013816	463	8.940530482	394	8.766885203	392	7.989214054	325	7.126362801	318	0.967174359	0.067902292	normal	0.349266477	-0.529921532	normal	0.881043769	-0.316107069	normal	0.297321432	-0.262816967	normal	--	--	Biological Process: chromosome segregation (GO:0007059);; Molecular Function: microtubule binding (GO:0008017);; Biological Process: cell division (GO:0051301);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1395)	Spindle and kinetochore-associated protein 1 GN=SKA1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: spindle and kinetochore-associated protein 1 isoform X1 [Galeopterus variegatus] 
ENSG00000154845(PPP4R1)	--	16.67806077	1237	18.14283863	1338	17.35468158	1224	19.24108692	1428	20.08865323	1478	19.10937816	1418	0.969278416	0.176114503	normal	0.977642239	0.12201035	normal	0.962693697	0.203728478	normal	0.401274226	0.165453559	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15424|0|hsa:9989|PPP4R1, MEG1, PP4(Rmeg), PP4R1; protein phosphatase 4, regulatory subunit 1; K15424 serine/threonine-protein phosphatase 4 regulatory subunit 1 (A)"	--	[T]	Signal transduction mechanisms	HEAT repeat;; HEAT repeats	Serine/threonine-protein phosphatase 4 regulatory subunit 1 GN=PPP4R1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 1 [Ceratotherium simum simum]
ENSG00000154856(APCDD1)	--	0.026375706	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Adenomatosis polyposis coli down-regulated 1	Protein APCDD1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protein APCDD1 [Ochotona princeps]
ENSG00000154864(PIEZO2)	--	3.713523465	368	3.621555413	316	4.165516174	363	3.279963698	229	3.169974304	413	3.11892725	380	0.0339819	-0.71138716	normal	0.824383245	0.363265995	normal	0.967740174	0.057504266	normal	0.923805752	-0.054399772	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF3595)	Piezo-type mechanosensitive ion channel component 2 GN=PIEZO2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: piezo-type mechanosensitive ion channel component 2 [Tupaia chinensis]
ENSG00000154889(MPPE1)	--	13.94640122	436	15.17704798	467	10.88323313	410	11.4647946	370	12.09602901	354	14.31144775	408	0.916986056	-0.266613816	normal	0.703344644	-0.419533865	normal	0.96987976	-0.015289665	normal	0.349515448	-0.23510055	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[L]	"Replication, recombination and repair"	Calcineurin-like phosphoesterase;; Calcineurin-like phosphoesterase superfamily domain	Metallophosphoesterase 1 GN=MPPE1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: metallophosphoesterase 1 isoform X1 [Equus caballus]
ENSG00000154914(USP43)	--	1.3898751	113	1.797716469	147	1.396529784	115	1.573260608	124	1.7942746	137	2.604304545	206	0.966723882	0.101862701	normal	0.962028577	-0.121768836	normal	0.032704742	0.82450723	normal	0.555035344	0.296594796	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11856|0|ggo:101137096|USP43; ubiquitin carboxyl-terminal hydrolase 43; K11856 ubiquitin carboxyl-terminal hydrolase 43 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 43 GN=USP43 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 43 [Galeopterus variegatus]
ENSG00000154917(RAB6B)	--	5.134100271	257	5.592358254	230	5.580898295	209	2.015113878	116	2.357923244	144	2.783846146	97	1.75E-05	-1.167798407	down	0.144278325	-0.691193013	normal	0.000278353	-1.103726867	down	0.000173661	-0.984920539	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07894|3.19204e-152|ssc:100522830|RAB6B; RAB6B, member RAS oncogene family; K07894 Ras-related protein Rab-6B (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Signal recognition particle receptor beta subunit;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B	Ras-related protein Rab-6B GN=RAB6B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-6B isoform X1 [Bos mutus]
ENSG00000154920(EME1)	--	8.474672161	441	7.104903161	355	8.250229218	436	6.864798356	327	6.272657713	326	6.048032986	318	0.583531389	-0.460449461	normal	0.957336302	-0.143734412	normal	0.584787657	-0.46170961	normal	0.115419089	-0.364513642	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: nuclease activity (GO:0004518);; 	"K10882|0|hsa:146956|EME1, MMS4L, SLX2A; essential meiotic structure-specific endonuclease 1; K10882 crossover junction endonuclease EME1 [EC:3.1.22.-] (A)"	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	--	--	ERCC4 domain	Crossover junction endonuclease EME1 GN=EME1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: crossover junction endonuclease EME1 isoform X3 [Galeopterus variegatus]
ENSG00000154930(ACSS1)	--	4.40224441	316	4.593173375	334	5.50221084	401	5.516288182	399	4.583759123	323	5.46699554	391	0.891212077	0.304312766	normal	0.965248591	-0.069420841	normal	0.968833392	-0.0445549	normal	0.87084398	0.061721366	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01895|0|ggo:101124103|ACSS1; acetyl-coenzyme A synthetase 2-like, mitochondrial isoform 1; K01895 acetyl-CoA synthetase [EC:6.2.1.1] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	"Acetyl-coenzyme A synthetase 2-like, mitochondrial (Precursor) GN=ACSS1 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: acetyl-coenzyme A synthetase 2-like, mitochondrial, partial [Ceratotherium simum simum]"
ENSG00000154945(ANKRD40)	--	26.3074	1986	26.53862	2012	23.67242	1778	25.4555	1917	27.915522	2096	25.77883	1942	0.984787412	-0.081783144	normal	0.986417868	0.037554198	normal	0.981850276	0.118899641	normal	0.940575645	0.022718184	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 40 GN=ANKRD40 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ankyrin repeat domain-containing protein 40-like isoform X1 [Physeter catodon]
ENSG00000154957(ZNF18)	--	3.62988199	218	3.010659586	179	3.037183704	179	2.511629594	140	2.134544734	122	2.524919401	151	0.208827448	-0.663843778	normal	0.558289089	-0.568648099	normal	0.938942424	-0.251387164	normal	0.110377206	-0.501091537	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:7566|ZNF18, HDSG1, KOX11, ZKSCAN6, ZNF535, ZSCAN38, Zfp535; zinc finger protein 18; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 18 GN=ZNF18 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 18 isoform X1 [Galeopterus variegatus]
ENSG00000154978(VOPP1)	--	60.94060475	3135	63.70738757	3355	67.22046218	3503	76.65166643	3978	69.52059621	3564	69.89337475	3617	0.939186618	0.312609299	normal	0.990155886	0.065729265	normal	0.99115748	0.037895067	normal	0.505470341	0.137830351	normal	--	--	--	--	--	--	--	--	"Vesicular, overexpressed in cancer, prosurvival protein 1 (Precursor) GN=VOPP1 OS=Homo sapiens (Human) PE=2 SV=1"	S	Function unknown	"PREDICTED: vesicular, overexpressed in cancer, prosurvival protein 1 [Felis catus]"
ENSG00000155008(APOOL)	--	8.0181528	550	9.74368261	688	7.513470582	554	8.287738625	578	7.455545217	566	8.136227255	587	0.97225388	0.040694716	normal	0.891650429	-0.302299144	normal	0.970684689	0.074984211	normal	0.813067828	-0.071359263	normal	--	--	Biological Process: cristae formation (GO:0042407);; Cellular Component: MICOS complex (GO:0061617);; 	--	--	[S]	Function unknown	Apolipoprotein O	MICOS complex subunit MIC27 (Precursor) GN=UNQ8193/PRO23204 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: apolipoprotein O-like isoform X1 [Ursus maritimus]
ENSG00000155011(DKK2)	--	0	0	0	0	0	0	0.071479465	1	0.059726784	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: negative regulation of Wnt signaling pathway (GO:0030178);; 	"K02165|1.13454e-178|hsa:27123|DKK2, DKK-2; dickkopf WNT signaling pathway inhibitor 2; K02165 dickkopf (A)"	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Dickkopf N-terminal cysteine-rich region	Dickkopf-related protein 2 (Precursor) GN=DKK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dickkopf-related protein 2 [Pteropus alecto] 
ENSG00000155016(CYP2U1)	--	2.388524863	183	2.718469349	195	2.74883575	203	3.636573164	269	3.575254644	270	3.257655524	247	0.531003627	0.521300745	normal	0.726924053	0.445113518	normal	0.922741458	0.272894101	normal	0.136173434	0.414689155	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07422|0|ggo:101138067|cytochrome P450 2U1-like; K07422 cytochrome P450, family 2, subfamily U, polypeptide 1 (A)"	Arachidonic acid metabolism (ko00590)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2U1 GN=CYP2U1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2U1-like [Mustela putorius furo]
ENSG00000155026(RSPH10B)	--	0.486994	28	0.639939	37	0.378339	21	0.985992	57	0.76057	43	0.622606	36	0.553303991	0.95721254	normal	0.977575363	0.188242922	normal	0.929974488	0.728804755	normal	0.289356656	0.637775324	normal	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat	Radial spoke head 10 homolog B GN=RSPH10B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: radial spoke head 10 homolog B2 [Tupaia chinensis]
ENSG00000155034(FBXL18)	--	15.66353	1355	16.438286	1512	18.627005	1626	17.29969905	1642	16.78020041	1525	18.74891006	1785	0.950256671	0.246075242	normal	0.983764021	-0.009066425	normal	0.980123897	0.12619332	normal	0.579168883	0.119563576	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10284|0|hsa:80028|FBXL18, Fbl18; F-box and leucine-rich repeat protein 18; K10284 F-box and leucine-rich repeat protein 18 (A)"	--	--	--	F-box-like;; F-box domain	F-box/LRR-repeat protein 18 GN=FBXL18 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 18 isoform X1 [Tupaia chinensis]
ENSG00000155066(PROM2)	--	0.054121047	4	0.06572339	6	0.03167555	2	0.027028331	2	0.092183366	6	0.086914351	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K15602|0|hsa:150696|PROM2, PROML2; prominin 2; K15602 prominin 2 (A)"	--	[R]	General function prediction only	Prominin	Prominin-2 (Precursor) GN=PROM2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: prominin-2 [Tupaia chinensis]
ENSG00000155085(AK9)	--	2.10802259	65	1.785221393	60	1.318420193	55	1.579989669	57	1.777014828	55	1.559357437	54	0.969953443	-0.214881216	normal	0.973210625	-0.143186527	normal	0.977619307	-0.033825006	normal	0.858519474	-0.138374598	normal	[F]	Nucleotide transport and metabolism	--	"K18533|0|hsa:221264|AK9, AK_9, AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1; adenylate kinase 9 (EC:2.7.4.6 2.7.4.4); K18533 adenylate/nucleoside-diphosphate kinase [EC:2.7.4.3 2.7.4.6] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Adenylate kinase;; AAA domain;; ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA domain;; AAA domain;; AAA domain;; AAA domain;; Zeta toxin;; AAA domain;; AAA ATPase domain;; Molybdopterin guanine dinucleotide synthesis protein B;; NACHT domain;; YHS domain;; RNA helicase;; AAA domain (dynein-related subfamily);; NTPase;; 50S ribosome-binding GTPase;; ABC transporter;; Holliday junction DNA helicase ruvB N-terminus;; Miro-like protein;; Ethanolamine utilisation - propanediol utilisation	Adenylate kinase 9 GN=AK9 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: adenylate kinase 9 [Equus przewalskii]
ENSG00000155090(KLF10)	--	28.45681	1611	23.229093	1299	25.330709	1406	32.472425	1819	22.350979	1254	20.700371	1165	0.978199154	0.144227286	normal	0.980111601	-0.072205078	normal	0.927239894	-0.279227626	normal	0.926926189	-0.049010479	normal	[R]	General function prediction only	--	K09209|0|pps:100976607|KLF10; Kruppel-like factor 10; K09209 krueppel-like factor 10/11 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Krueppel-like factor 10 GN=KLF10 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: Krueppel-like factor 10 [Ursus maritimus]
ENSG00000155093(PTPRN2)	--	1.36246192	134	0.815227158	54	0.760131073	60	0.192929551	8	0.059292899	5	0.160234407	7	0	-3.857256505	down	1.24E-07	-3.110219345	down	1.35E-07	-2.860708863	down	0.001634743	-3.65463073	down	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K07817|0|hsa:5799|PTPRN2, IA-2beta, IAR, ICAAR, PTPRP, R-PTP-N2; protein tyrosine phosphatase, receptor type, N polypeptide 2 (EC:3.1.3.48); K07817 receptor-type tyrosine-protein phosphatase N [EC:3.1.3.48] (A)"	Type I diabetes mellitus (ko04940)	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase;; Protein-tyrosine phosphatase receptor IA-2;; RESP18 domain	Receptor-type tyrosine-protein phosphatase N2 (Precursor) GN=PTPRN2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase N2 [Oryctolagus cuniculus]
ENSG00000155096(AZIN1)	--	55.17605	3111	57.04783272	3185	64.55534005	3526	71.85324178	3979	61.76189626	3412	59.61934135	3220	0.929917619	0.324053435	normal	0.989440605	0.077861994	normal	0.986734818	-0.139200729	normal	0.694750469	0.089806992	normal	[E]	Amino acid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; 	--	--	[E]	Amino acid transport and metabolism	"Pyridoxal-dependent decarboxylase, pyridoxal binding domain;; Pyridoxal-dependent decarboxylase, C-terminal sheet domain"	Antizyme inhibitor 1 GN=AZIN1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	antizyme inhibitor 1 [Leptonychotes weddellii] 
ENSG00000155097(ATP6V1C1)	--	29.72014217	1609	39.57003604	2055	36.01489542	1711	28.85876063	1565	27.21655568	1551	36.64299996	1923	0.983083873	-0.07076541	normal	0.678673699	-0.427003249	normal	0.976993631	0.160094019	normal	0.690306296	-0.113891027	normal	--	--	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V1 domain (GO:0033180);; "	"K02148|0|ptr:464326|ATP6V1C1; ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1; K02148 V-type H+-transporting ATPase subunit C (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	V-ATPase subunit C	V-type proton ATPase subunit C 1 GN=ATP6V1C1 OS=Homo sapiens (Human) PE=1 SV=4	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit C 1 [Oryctolagus cuniculus] 
ENSG00000155099(TMEM55A)	--	5.48062544	190	6.618377827	214	6.341565479	209	3.8921669	134	3.993038024	139	4.395636182	139	0.62798289	-0.529471838	normal	0.286021083	-0.638309904	normal	0.422930634	-0.591425186	normal	0.043056142	-0.594270349	normal	--	--	"Molecular Function: phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity (GO:0034597);; Biological Process: phosphatidylinositol dephosphorylation (GO:0046856);; "	"K13084|0|ptr:464281|TMEM55A; transmembrane protein 55A; K13084 phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78] (A)"	--	[R]	General function prediction only	Transmembrane protein 55A	"Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase GN=TMEM55A OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase [Camelus bactrianus]"
ENSG00000155100(OTUD6B)	--	10.271365	489	9.861673	469	11.95376	556	10.402992	502	8.6768646	411	8.663762	412	0.971620543	0.006998932	normal	0.942570068	-0.211148155	normal	0.621313694	-0.439338437	normal	0.378310302	-0.213950647	normal	--	--	--	K18342|0|ptr:464282|OTUD6B; OTU domain containing 6B; K18342 OTU domain-containing protein 6 [EC:3.4.19.12] (A)	--	[TO]	"Signal transduction mechanisms;; Posttranslational modification, protein turnover, chaperones"	OTU-like cysteine protease;; Peptidase C65 Otubain	OTU domain-containing protein 6B GN=OTUD6B OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: OTU domain-containing protein 6B [Odobenus rosmarus divergens]
ENSG00000155111(CDK19)	--	5.145203464	535	6.792558552	641	6.131496858	578	5.229819392	547	5.175761411	467	6.390016	664	0.972540684	0.001166365	normal	0.485174801	-0.477003919	normal	0.953185403	0.191354849	normal	0.800513651	-0.084643444	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02208|0|pps:100977722|CDK19; cyclin-dependent kinase 19; K02208 cyclin-dependent kinase 8/11 [EC:2.7.11.22 2.7.11.23] (A)	--	[K]	Transcription	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 19 GN=CDK19 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cyclin-dependent kinase 19 [Pteropus alecto] 
ENSG00000155115(GTF3C6)	--	30.3673	460	42.4485	645	35.52224	577	39.59542	656	29.70910959	489	38.3105	588	0.457862898	0.479881332	normal	0.678193211	-0.41975698	normal	0.973283276	0.018904312	normal	0.965782714	0.02144398	normal	--	--	--	"K15203|3.03289e-138|nle:100582308|GTF3C6; general transcription factor IIIC, polypeptide 6, alpha 35kDa; K15203 general transcription factor 3C polypeptide 6 (A)"	--	--	--	TFIIIC subunit	General transcription factor 3C polypeptide 6 GN=GTF3C6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor 3C polypeptide 6 [Pteropus alecto] 
ENSG00000155158(TTC39B)	--	2.463054841	226	1.641892517	174	2.747645396	181	1.45497271	135	1.550304924	134	1.127810879	119	0.051881681	-0.767366101	normal	0.861303107	-0.394363052	normal	0.450701166	-0.607018407	normal	0.045082278	-0.604136402	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF3808);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 39B GN=TTC39B OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: tetratricopeptide repeat domain 39B [Ceratotherium simum simum]
ENSG00000155189(AGPAT5)	--	30.92760821	1800	30.538802	1790	30.84906	1741	30.9030388	1820	25.47361272	1520	26.52456688	1544	0.985874533	-0.01487809	normal	0.948384431	-0.25707882	normal	0.971886517	-0.181367493	normal	0.465069267	-0.148148402	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	--	--	[I]	Lipid transport and metabolism	Acyltransferase	1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon GN=AGPAT5 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon-like isoform X1 [Tupaia chinensis]
ENSG00000155229(MMS19)	--	23.07582916	1409	19.62268151	1221	20.38873382	1295	23.31158554	1451	24.0302406	1484	20.39364022	1268	0.983499165	0.011531254	normal	0.94149505	0.259709173	normal	0.981907389	-0.038643188	normal	0.748078302	0.077190104	normal	--	--	--	K15075|0|ggo:101149547|MMS19; MMS19 nucleotide excision repair protein homolog isoform 1; K15075 DNA repair/transcription protein MET18/MMS19 (A)	--	[LK]	"Replication, recombination and repair;; Transcription"	RNAPII transcription regulator C-terminal;; Dos2-interacting transcription regulator of RNA-Pol-II;; HEAT repeats	MMS19 nucleotide excision repair protein homolog GN=MMS19 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: MMS19 nucleotide excision repair protein homolog isoform X1 [Physeter catodon]
ENSG00000155252(PI4K2A)	--	17.35024123	1329	18.74580313	1459	19.6446508	1534	20.32019543	1519	18.90369957	1383	20.87671858	1584	0.972967071	0.161773479	normal	0.979789582	-0.098500401	normal	0.984041269	0.037945596	normal	0.9074175	0.032777692	normal	--	--	Molecular Function: kinase activity (GO:0016301);; 	K13711|0|ptr:450656|PI4K2A; phosphatidylinositol 4-kinase type 2 alpha; K13711 phosphatidylinositol 4-kinase type 2 [EC:2.7.1.67] (A)	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	Phosphatidylinositol 3- and 4-kinase	Phosphatidylinositol 4-kinase type 2-alpha GN=PI4K2A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-kinase type 2-alpha [Mustela putorius furo]
ENSG00000155254(MARVELD1)	--	38.8065	2026	45.5021	2390	42.7448	2260	36.8761	1920	33.0806	1721	40.3488	2113	0.98334099	-0.108275761	normal	0.40209808	-0.494819307	normal	0.98467893	-0.105248595	normal	0.174410704	-0.235365048	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	MARVEL domain-containing protein 1 GN=MARVELD1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: MARVEL domain-containing protein 1 [Dasypus novemcinctus]
ENSG00000155256(ZFYVE27)	--	9.990097263	573	10.46487456	616	10.83860793	648	10.83690977	624	10.06637681	575	10.99441519	642	0.969745392	0.09194235	normal	0.966019498	-0.120488706	normal	0.974365119	-0.02166117	normal	0.964064609	-0.017862357	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	FYVE zinc finger	Protrudin GN=ZFYVE27 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protrudin isoform X1 [Oryctolagus cuniculus] 
ENSG00000155265(GOLGA7B)	--	1.654644425	170	2.104241563	191	1.574943073	171	2.877240019	282	3.221359631	237	4.082282111	339	0.087793966	0.694408301	normal	0.915469327	0.287838583	normal	0.000268951	0.972771043	normal	0.006260404	0.668727094	normal	--	--	--	--	--	[S]	Function unknown	Golgin subfamily A member 7/ERF4 family	Golgin subfamily A member 7B GN=GOLGA7B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: golgin subfamily A member 7B [Canis lupus familiaris] 
ENSG00000155269(GPR78)	--	0	0	0	0	0	0	0	0	0	0	0.0482569	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08418|0|hsa:27201|GPR78; G protein-coupled receptor 78; K08418 G protein-coupled receptor 78 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 78 GN=GPR78 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 78 [Tupaia chinensis]
ENSG00000155275(TRMT44)	--	1.775288962	315	1.962905071	338	2.6307449	332	2.52355745	302	2.257076485	269	2.595899	382	0.964206289	-0.091181265	normal	0.852237235	-0.349088607	normal	0.947899115	0.19327659	normal	0.857800023	-0.068161831	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	"K15447|0|hsa:152992|TRMT44, C4orf23, METTL19, TRM44; tRNA methyltransferase 44 homolog (S. cerevisiae) (EC:2.1.1.211); K15447 tRNASer (uridine44-2'-O)-methyltransferase [EC:2.1.1.211] (A)"	--	[S]	Function unknown	Predicted AdoMet-dependent methyltransferase	Probable tRNA (uracil-O(2)-)-methyltransferase GN=TRMT44 OS=Homo sapiens (Human) PE=2 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: probable tRNA (uracil-O(2)-)-methyltransferase [Galeopterus variegatus]
ENSG00000155287(SLC25A28)	--	12.3185269	332	13.3900996	338	10.8378596	317	11.86469	316	11.8329336	332	11.02145143	353	0.963461004	-0.101608876	normal	0.966557101	-0.047054134	normal	0.9578642	0.146232529	normal	1	-0.000631264	normal	--	--	--	"K15113|0|mcf:102141779|SLC25A28; solute carrier family 25 (mitochondrial iron transporter), member 28; K15113 solute carrier family 25 (mitochondrial iron transporter), member 28/37 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitoferrin-2 GN=SLC25A28 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: mitoferrin-2 [Galeopterus variegatus]
ENSG00000155304(HSPA13)	--	16.001	975	19.9715	1209	19.4056	1152	13.8096	851	12.2262	745	18.3894	1121	0.947228456	-0.226692597	normal	0.005234143	-0.718771281	normal	0.980271588	-0.047582556	normal	0.259034915	-0.316458622	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	"K09491|0|hsa:6782|HSPA13, STCH; heat shock protein 70kDa family, member 13; K09491 stress 70 protein chaperone microsome-associated 60kDa protein (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein	Heat shock 70 kDa protein 13 (Precursor) GN=HSPA13 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 13 [Canis lupus familiaris]
ENSG00000155307(SAMSN1)	--	0.047729092	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Lymphocyte signaling adaptor protein;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Variant SH3 domain	SAM domain-containing protein SAMSN-1 GN=SAMSN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SAM domain-containing protein SAMSN-1 isoform X2 [Ursus maritimus]
ENSG00000155313(USP25)	--	11.19349476	964	10.62006911	917	10.86968102	933	8.886299957	753	9.823317724	826	8.938227293	777	0.752835516	-0.386516457	normal	0.962776905	-0.171907627	normal	0.921670688	-0.271770503	normal	0.132349113	-0.277339121	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11849|0|hsa:29761|USP25, USP21; ubiquitin specific peptidase 25 (EC:3.4.19.12); K11849 ubiquitin carboxyl-terminal hydrolase 25/28 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin interaction motif	Ubiquitin carboxyl-terminal hydrolase 25 GN=USP25 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 25 [Galeopterus variegatus]
ENSG00000155324(GRAMD3)	--	2.000645056	96	2.992104494	129	2.906498928	142	5.747366467	236	4.245167823	196	9.345149715	364	6.79E-06	1.253645589	up	0.504591156	0.576536366	normal	1.78E-08	1.340515031	up	0.033854162	1.097457163	normal	--	--	--	--	--	[S]	Function unknown	GRAM domain	GRAM domain-containing protein 3 GN=GRAMD3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: GRAM domain-containing protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000155329(ZCCHC10)	--	10.84993723	212	12.874702	197	8.86484149	219	21.019054	227	12.75995985	209	12.1716384	224	0.965200311	0.067324215	normal	0.964281553	0.063408151	normal	0.966783259	0.024111786	normal	0.915887742	0.050576909	normal	--	--	--	--	--	[R]	General function prediction only	Zinc knuckle	Zinc finger CCHC domain-containing protein 10 GN=ZCCHC10 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger CCHC domain-containing protein 10 [Oryctolagus cuniculus]
ENSG00000155330(C16orf87)	--	7.648318151	245	7.230720547	244	6.599950432	221	5.89172105	205	6.309259476	207	7.203320712	242	0.916005409	-0.286026025	normal	0.928212399	-0.256945694	normal	0.960740321	0.121872045	normal	0.713816578	-0.139408912	normal	--	--	--	--	--	--	--	--	UPF0547 protein C16orf87 GN=C16orf87 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0547 protein C16orf87 homolog isoform 2 [Dasypus novemcinctus]
ENSG00000155363(MOV10)	--	14.862299	1097	14.11979	1055	13.43295	1018	10.474527	769	12.118357	888	12.91153	955	0.184897971	-0.542427577	normal	0.926797885	-0.269616115	normal	0.975406644	-0.100302494	normal	0.086223808	-0.29993494	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K18422|0|ptr:457099|MOV10; Mov10 RISC complex RNA helicase; K18422 helicase MOV-10 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	AAA domain;; AAA domain;; AAA domain;; Part of AAA domain	Putative helicase MOV-10 GN=MOV10 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: putative helicase MOV-10 isoform X1 [Galeopterus variegatus] 
ENSG00000155366(RHOC)	--	101.229203	2325	97.41745541	2166	95.19548288	2265	144.1647951	3291	141.4321454	3153	107.7225949	2427	0.522211008	0.470200727	normal	0.312847506	0.519962851	normal	0.986180341	0.091312709	normal	0.049128993	0.370929611	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07857|3.10142e-90|oaa:100681498|RHOC; ras homolog family member C; K07857 Ras homolog gene family, member C (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoC (Precursor) GN=RHOC OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoC [Ornithorhynchus anatinus]
ENSG00000155368(DBI)	--	256.6934023	1996	282.3695106	2260	287.052262	2315	187.8968945	1550	159.2782392	1232	278.060541	2221	0.762889224	-0.395329373	normal	1.98E-05	-0.895922006	normal	0.986851608	-0.068048854	normal	0.213702534	-0.413342546	normal	[I]	Lipid transport and metabolism	Molecular Function: fatty-acyl-CoA binding (GO:0000062);; 	"K08762|5.5332e-71|pon:100434084|DBI; diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein); K08762 diazepam-binding inhibitor (GABA receptor modulator, acyl-CoA-binding protein) (A)"	PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	Acyl CoA binding protein	Acyl-CoA-binding protein GN=DBI OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	"Chain A, Structure Of Bovine Acyl-Coa Binding Protein In Orthorhombic Crystal Form "
ENSG00000155380(SLC16A1)	--	22.61852764	1326	22.97471369	1321	22.13970003	1264	34.60255525	2026	32.33765655	1864	29.65438811	1715	0.088385551	0.580173626	normal	0.474659	0.474885113	normal	0.631250747	0.431475834	normal	0.000673393	0.497400956	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08179|0|hsa:6566|SLC16A1, HHF7, MCT, MCT1, MCT1D; solute carrier family 16 (monocarboxylate transporter), member 1; K08179 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 1 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; MFS_1 like family	Monocarboxylate transporter 1 GN=SLC16A1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: monocarboxylate transporter 1 [Galeopterus variegatus] 
ENSG00000155393(HEATR3)	--	8.06828	474	9.53828	557	9.77208	567	10.33861	628	9.5424	572	9.8138	575	0.785327393	0.373989131	normal	0.97223539	0.016866075	normal	0.973160951	0.011890287	normal	0.620321721	0.130208823	normal	--	--	--	--	--	--	--	HEAT repeats;; HEAT repeat;; HEAT-like repeat;; Armadillo/beta-catenin-like repeat	HEAT repeat-containing protein 3 GN=HEATR3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: HEAT repeat-containing protein 3 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000155428(TRIM74)	--	0.27422306	6	0	0	0.129290402	2	0.318241457	7	0.267382362	5	0.405014316	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12024|0|hsa:378108|TRIM74, TRIM50C; tripartite motif containing 74; K12024 tripartite motif-containing protein 50/73/74 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; RING-type zinc-finger;; Ring finger domain"	Tripartite motif-containing protein 74 GN=TRIM74 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM50 [Tupaia chinensis] 
ENSG00000155438(NIFK)	--	33.54366709	827	33.15474279	819	32.10904254	757	25.264386	695	27.41113129	696	23.68059258	611	0.911871688	-0.281135978	normal	0.929693213	-0.255689891	normal	0.876074676	-0.316706706	normal	0.136907442	-0.285077184	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K14838|0|hsa:84365|NIFK, MKI67IP, Nopp34; nucleolar protein interacting with the FHA domain of MKI67; K14838 nucleolar protein 15 (A)"	--	[R]	General function prediction only	"FHA Ki67 binding domain of hNIFK;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	MKI67 FHA domain-interacting nucleolar phosphoprotein GN=NIFK OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: MKI67 FHA domain-interacting nucleolar phosphoprotein-like [Oryctolagus cuniculus]
ENSG00000155463(OXA1L)	--	102.470646	2515	103.799139	2547	96.2448664	2361	100.7556802	2484	112.1567207	2734	114.4200378	2850	0.988277857	-0.048695556	normal	0.987455806	0.080741449	normal	0.957374041	0.263118827	normal	0.655661167	0.099326654	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein insertion into membrane (GO:0051205);; 	"K03217|0|hsa:5018|OXA1L, OXA1; oxidase (cytochrome c) assembly 1-like; K03217 YidC/Oxa1 family membrane protein insertase (A)"	Protein export (ko03060)	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	60Kd inner membrane protein	Mitochondrial inner membrane protein OXA1L (Precursor) GN=OXA1L OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: mitochondrial inner membrane protein OXA1L-like [Lipotes vexillifer]
ENSG00000155465(SLC7A7)	--	0.464245127	8	0.390774973	13	0.24987281	7	5.313933778	152	7.585698406	210	12.430117	346	0	3.98078866	up	0	3.845161238	up	0	5.343836432	up	5.98E-07	4.640710185	up	[E]	Amino acid transport and metabolism	Biological Process: amino acid transmembrane transport (GO:0003333);; Biological Process: transport (GO:0006810);; Molecular Function: amino acid transmembrane transporter activity (GO:0015171);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K13867|0|ptr:452786|SLC7A7; solute carrier family 7 (amino acid transporter light chain, y+L system), member 7; K13867 solute carrier family 7 (L-type amino acid transporter), member 7 (A)"	Protein digestion and absorption (ko04974)	[E]	Amino acid transport and metabolism	Amino acid permease;; Amino acid permease	Y+L amino acid transporter 1 GN=SLC7A7 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: Y+L amino acid transporter 1 isoform X1 [Tupaia chinensis] 
ENSG00000155495(MAGEC1)	--	0.0158515	1	0.0478132	3	0.031441	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family	Melanoma-associated antigen C1 GN=MAGEC1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: melanoma-associated antigen C2-like [Galeopterus variegatus]
ENSG00000155506(LARP1)	--	51.99454311	7413	56.39898824	8008	52.03921382	7572	57.049359	7968	58.69600453	8208	59.522541	8359	0.99481327	0.073313215	normal	0.9953604	0.014159558	normal	0.993375082	0.134338962	normal	0.782485592	0.072562139	normal	[OJ]	"Posttranslational modification, protein turnover, chaperones;; Translation, ribosomal structure and biogenesis"	--	"K18757|0|hsa:23367|LARP1, LARP; La ribonucleoprotein domain family, member 1; K18757 la-related protein 1 (A)"	--	[OJ]	"Posttranslational modification, protein turnover, chaperones;; Translation, ribosomal structure and biogenesis"	La domain	La-related protein 1 GN=LARP1 OS=Homo sapiens (Human) PE=1 SV=2	JO	"Translation, ribosomal structure and biogenesis;; Posttranslational modification, protein turnover, chaperones"	"PREDICTED: LOW QUALITY PROTEIN: La ribonucleoprotein domain family, member 1 [Odobenus rosmarus divergens]"
ENSG00000155508(CNOT8)	--	20.32058385	790	22.12140824	866	22.54004014	860	23.3219214	885	22.86161047	864	25.79242001	999	0.969394446	0.132748533	normal	0.977124204	-0.024719054	normal	0.954770113	0.207517708	normal	0.659599028	0.106452631	normal	[A]	RNA processing and modification	--	"K12581|0|umr:103664556|CNOT8; CCR4-NOT transcription complex, subunit 8; K12581 CCR4-NOT transcription complex subunit 7/8 (A)"	RNA degradation (ko03018)	[A]	RNA processing and modification	CAF1 family ribonuclease	CCR4-NOT transcription complex subunit 8 GN=CNOT8 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 8 isoform X2 [Monodelphis domestica]
ENSG00000155530(LRGUK)	--	0.118762541	5	0.164410083	7	0.234600382	9	0.1096316	5	0.4608225	20	0.072945606	4	--	--	--	0.884358178	1.318772788	normal	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	--	--	--	[F]	Nucleotide transport and metabolism	Guanylate kinase;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich Repeat;; Leucine rich repeat	Leucine-rich repeat and guanylate kinase domain-containing protein GN=LRGUK OS=Homo sapiens (Human) PE=2 SV=1	FT	Nucleotide transport and metabolism;; Signal transduction mechanisms	PREDICTED: leucine-rich repeat and guanylate kinase domain-containing protein [Tupaia chinensis]
ENSG00000155542(SETD9)	--	3.568656116	59	3.157195	58	3.8380781	74	3.264956395	63	3.495210543	58	4.145629512	49	0.976191437	0.06223612	normal	0.975770149	-0.020882089	normal	0.85701553	-0.588161334	normal	0.786760395	-0.189520924	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SET domain	SET domain-containing protein 9 GN=SETD9 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: SET domain-containing protein 9 [Orycteropus afer afer]
ENSG00000155545(MIER3)	--	7.437316602	570	7.398418979	563	7.073734724	528	6.37502009	492	7.375370417	563	6.582269567	504	0.931403946	-0.242431689	normal	0.972133247	-0.021369159	normal	0.969591603	-0.075185202	normal	0.685025699	-0.112604695	normal	--	--	--	--	--	--	--	ELM2 domain;; Myb-like DNA-binding domain	Mesoderm induction early response protein 3 GN=MIER3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: mesoderm induction early response protein 3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000155561(NUP205)	--	24.997123	2783	24.421759	2720	26.38645	2906	27.394754	3054	26.57954	2940	22.36658	2489	0.987635714	0.103172506	normal	0.98766459	0.090734416	normal	0.969238149	-0.231629528	normal	0.981741102	-0.009021877	normal	--	--	Cellular Component: nuclear pore (GO:0005643);; 	"K14310|0|hsa:23165|NUP205, C7orf14; nucleoporin 205kDa; K14310 nuclear pore complex protein Nup205 (A)"	RNA transport (ko03013)	[S]	Function unknown	Protein of unknown function (DUF3414)	Nuclear pore complex protein Nup205 GN=NUP205 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: nuclear pore complex protein Nup205 isoform X2 [Equus przewalskii]
ENSG00000155592(ZKSCAN2)	--	1.77365	262	2.00417	297	1.71517	252	1.54661	229	1.74706	257	1.68259	249	0.940109342	-0.223647267	normal	0.936150391	-0.228867073	normal	0.966945421	-0.025415991	normal	0.632646487	-0.163065475	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:342357|ZKSCAN2, ZNF694, ZSCAN31, ZSCAN34; zinc finger with KRAB and SCAN domains 2; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Myb/SANT-like DNA-binding domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Myb-like DNA-binding domain;; KRAB box"	Zinc finger protein with KRAB and SCAN domains 2 GN=ZKSCAN2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein with KRAB and SCAN domains 2 [Ceratotherium simum simum]
ENSG00000155621(C9orf85)	--	8.269850099	213	7.444450104	207	10.04028	262	13.240084	341	10.5159832	276	11.36578268	290	0.120825264	0.644381948	normal	0.815691919	0.391128767	normal	0.958726548	0.137440316	normal	0.136043971	0.389980624	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2039)	Uncharacterized protein C9orf85 GN=C9orf85 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: chromosome unknown open reading frame, human C9orf85 [Chrysochloris asiatica]"
ENSG00000155629(PIK3AP1)	--	1.356910217	121	1.093715526	104	1.492440992	126	1.7297678	160	2.423736705	229	2.17902755	206	0.893659925	0.368156358	normal	0.000186425	1.106229899	up	0.175360389	0.694348423	normal	0.011107675	0.741294953	normal	--	--	--	"K12230|0|hsa:118788|PIK3AP1, BCAP; phosphoinositide-3-kinase adaptor protein 1; K12230 phosphoinositide 3-kinase adapter protein 1 (A)"	PI3K-Akt signaling pathway (ko04151);; B cell receptor signaling pathway (ko04662)	--	--	"Dof, BCAP, and BANK (DBB) motif,"	Phosphoinositide 3-kinase adapter protein 1 GN=PIK3AP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphoinositide 3-kinase adapter protein 1 [Ceratotherium simum simum]
ENSG00000155636(RBM45)	--	6.0164232	236	7.603307943	294	6.928200794	244	4.952944442	179	5.62137801	205	4.595815302	173	0.78015515	-0.426460067	normal	0.448304429	-0.538283772	normal	0.616622025	-0.500696587	normal	0.064462578	-0.496054649	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 45 GN=RBM45 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: RNA-binding protein 45 isoform X1 [Oryctolagus cuniculus]
ENSG00000155657(TTN)	--	0.060999442	114	0.060722066	112	0.055805199	103	0.061721017	117	0.045725942	84	0.06293565	117	0.969705613	0.006555236	normal	0.887198912	-0.429739194	normal	0.961796112	0.173185524	normal	0.912431504	-0.07055969	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K12567|0|hsa:7273|TTN, CMD1G, CMH9, CMPD4, EOMFC, HMERF, LGMD2J, MYLK5, TMD; titin (EC:2.7.11.1); K12567 titin [EC:2.7.11.1] (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; PPAK motif;; CD80-like C2-set immunoglobulin domain;; Titin Z;; Protein kinase domain;; Tissue factor;; Natural killer cell receptor 2B4;; Immunoglobulin C1-set domain;; SusE outer membrane protein;; Protein tyrosine kinase;; Alphaherpesvirus glycoprotein I;; Y_Y_Y domain	Titin GN=TTN OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: titin-like [Tupaia chinensis]
ENSG00000155659(VSIG4)	--	0	0	0	0	0	0	0	0	0	0	0.053233024	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	V-set and immunoglobulin domain-containing protein 4 (Precursor) GN=VSIG4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: V-set and immunoglobulin domain-containing protein 4-like isoform X1 [Physeter catodon]
ENSG00000155660(PDIA4)	--	138.366509	8161	124.50606	7384	131.272498	7762	130.535395	7710	125.60204	7363	121.426729	7152	0.994103175	-0.112825487	normal	0.994944622	-0.025530173	normal	0.993315096	-0.126347486	normal	0.717992377	-0.089980626	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: cell redox homeostasis (GO:0045454);; 	"K09582|0|hsa:9601|PDIA4, ERP70, ERP72, ERp-72; protein disulfide isomerase family A, member 4 (EC:5.3.4.1); K09582 protein disulfide-isomerase A4 [EC:5.3.4.1] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Thyroid hormone synthesis (ko04918);; Vibrio cholerae infection (ko05110)	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like domain;; Thioredoxin-like;; Thioredoxin-like;; Calsequestrin;; AhpC/TSA family;; Thioredoxin;; Redoxin	Protein disulfide-isomerase A4 (Precursor) GN=PDIA4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein disulfide-isomerase A4 [Galeopterus variegatus]
ENSG00000155666(KDM8)	--	0.960588791	51	1.847657011	83	1.00074818	48	1.140232855	61	1.404984041	75	1.032766402	54	0.971396879	0.221375825	normal	0.966713042	-0.164492763	normal	0.975867046	0.156968659	normal	0.971095564	0.040005156	normal	--	--	--	--	--	[BT]	Chromatin structure and dynamics;; Signal transduction mechanisms	Cupin-like domain;; Cupin superfamily protein	Lysine-specific demethylase 8 GN=KDM8 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: lysine-specific demethylase 8 [Galeopterus variegatus] 
ENSG00000155714(PDZD9)	--	0.120819209	2	0	0	0	0	0.059862155	1	0.058818259	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PDZ domain;; PDZ domain (Also known as DHR or GLGF)	PDZ domain-containing protein 9 GN=PDZD9 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: PDZ domain-containing protein 9 [Galeopterus variegatus]
ENSG00000155719(OTOA)	--	0.039639237	2	0	0	0.03886058	1	0.01988957	1	0	0	0.019713093	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Otoancorin (Precursor) GN=OTOA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: otoancorin isoform 1 [Odobenus rosmarus divergens]
ENSG00000155729(KCTD18)	--	11.352	527	9.57696	449	11.20656	510	6.47225	302	6.56	304	7.89537	361	0.00116567	-0.830842555	normal	0.199758313	-0.581673612	normal	0.403810467	-0.505000889	normal	0.000928557	-0.640401619	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD18 GN=KCTD18 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD18 isoform 1 [Dasypus novemcinctus]
ENSG00000155744(FAM126B)	--	1.898260523	260	2.304442305	286	2.7420169	289	1.9536618	269	2.13712	251	1.8733151	235	0.967167415	0.018156803	normal	0.9428036	-0.208576068	normal	0.899625004	-0.304927399	normal	0.620321721	-0.166815687	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Hyccin	Protein FAM126B GN=FAM126B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein FAM126B [Orcinus orca]
ENSG00000155749(ALS2CR12)	--	0	0	0	0	0.100755093	3	0.025754519	1	0.165572052	3	0.130422324	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein GN=ALS2CR12 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: amyotrophic lateral sclerosis 2 chromosomal region candidate gene 12 protein isoform X1 [Tupaia chinensis] 
ENSG00000155754(ALS2CR11)	--	0.00909072	1	0	0	0.07318585	4	0.0181081	2	0	0	0.0448774	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 11 protein GN=ALS2CR11 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: putative leucine-rich repeat-containing protein DDB_G0290503-like [Balaenoptera acutorostrata scammoni]
ENSG00000155755(TMEM237)	--	18.583491	815	15.88478204	652	19.11223196	839	10.00654449	507	9.652670893	474	8.754783915	414	0.007239612	-0.713922752	normal	0.471668547	-0.480099434	normal	1.38E-06	-1.024646662	down	1.15E-05	-0.746618577	normal	--	--	--	--	--	--	--	Transmembrane protein 237	Transmembrane protein 237 GN=TMEM237 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 237 isoform 2 [Orcinus orca]
ENSG00000155760(FZD7)	--	8.07649	487	8.06924	494	7.20949	440	2.57966	157	3.92114	236	3.86545	234	2.76E-14	-1.654285832	down	3.38E-06	-1.082244323	down	0.000312946	-0.914901875	normal	3.98E-10	-1.200526016	down	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	K02432|0|ggo:101150664|FZD7; LOW QUALITY PROTEIN: frizzled-7; K02432 frizzled 1/7 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-7 (Precursor) GN=FZD7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: frizzled-7 [Galeopterus variegatus]
ENSG00000155761(SPAG17)	--	0.02942664	5	0.0879511	10	0.1025851	12	0.0724756	5	0.0564619	5	0.0434412	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Flagellar-associated PapD-like	Sperm-associated antigen 17 GN=SPAG17 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: sperm-associated antigen 17 [Ceratotherium simum simum]
ENSG00000155792(DEPTOR)	--	1.553881745	72	1.492461347	70	1.189850848	53	0.796567425	37	1.341982983	62	1.328924662	62	0.309526213	-0.962130958	normal	0.968128638	-0.192100335	normal	0.970984912	0.21237655	normal	0.629099757	-0.296548563	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	"Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	DEP domain-containing mTOR-interacting protein GN=DEPTOR OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: DEP domain-containing mTOR-interacting protein [Mustela putorius furo]
ENSG00000155816(FMN2)	--	4.1643981	500	3.9323638	468	3.981695081	482	3.579804717	429	2.798110061	307	2.737565	334	0.926044374	-0.25094918	normal	0.099568897	-0.627174498	normal	0.309443101	-0.535446738	normal	0.025420539	-0.460538288	normal	--	--	--	K02184|0|hsa:56776|FMN2; formin 2; K02184 formin 2 (A)	Dorso-ventral axis formation (ko04320)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Formin Homology Region 1	Formin-2 GN=FMN2 OS=Homo sapiens (Human) PE=1 SV=4	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: formin-2 [Ceratotherium simum simum]
ENSG00000155827(RNF20)	--	18.79379436	1751	22.11468558	1819	22.13800389	1890	19.956758	1760	21.8723779	1756	23.16459232	1674	0.985484942	-0.023415425	normal	0.983956629	-0.072218143	normal	0.972891476	-0.183222267	normal	0.677267823	-0.094396254	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10696|0|ptr:464625|RNF20; ring finger protein 20, E3 ubiquitin protein ligase; K10696 E3 ubiquitin-protein ligase BRE1 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase BRE1A GN=RNF20 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase BRE1A [Ceratotherium simum simum]
ENSG00000155846(PPARGC1B)	--	1.598316462	341	1.102386046	246	1.364301269	290	1.502789716	332	1.377725819	299	1.074223853	240	0.966309334	-0.069105182	normal	0.924315474	0.258616642	normal	0.915179375	-0.279704079	normal	0.9508736	-0.031988163	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K17962|0|ptr:471692|PPARGC1B; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; K17962 peroxisome proliferator-activated receptor gamma coactivator 1-beta (A)"	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Peroxisome proliferator-activated receptor gamma coactivator 1-beta GN=PPARGC1B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: peroxisome proliferator-activated receptor gamma coactivator 1-beta isoform X1 [Galeopterus variegatus]
ENSG00000155849(ELMO1)	--	4.102479217	214	4.508630661	204	2.193737595	154	1.38011417	43	0.826679625	69	1.787320464	118	5.55E-16	-2.305063269	down	3.79E-08	-1.564396005	down	0.882123212	-0.388068287	normal	0.000400979	-1.333159485	down	--	--	--	K12366|0|ptr:463354|ELMO1; engulfment and cell motility 1; K12366 engulfment and cell motility protein 1 (A)	Chemokine signaling pathway (ko04062);; Bacterial invasion of epithelial cells (ko05100)	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3361);; ELMO/CED-12 family	Engulfment and cell motility protein 1 GN=ELMO1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: engulfment and cell motility protein 1 isoform 1 [Dasypus novemcinctus] 
ENSG00000155850(SLC26A2)	--	14.376412	1770	14.487277	1763	16.2493	1981	19.6745	2469	15.9088	1981	18.239	2273	0.58733474	0.449013879	normal	0.978848196	0.146651127	normal	0.974532524	0.189941897	normal	0.1164934	0.264677084	normal	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14701|0|hsa:1836|SLC26A2, D5S1708, DTD, DTDST, EDM4, MST153, MSTP157; solute carrier family 26 (anion exchanger), member 2; K14701 solute carrier family 26 (sulfate anion transporter), member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; STAS domain;; Sulfate transporter N-terminal domain with GLY motif	Sulfate transporter GN=SLC26A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	sulfate transporter [Equus caballus] 
ENSG00000155858(LSM11)	--	1.908256	195	1.631034296	168	2.03949785	207	2.420118241	250	3.1689684	324	2.6291211	270	0.89176172	0.325352943	normal	0.001207344	0.92004093	normal	0.84134302	0.372646802	normal	0.032066349	0.545696947	normal	--	--	--	--	--	--	--	LSM domain	U7 snRNA-associated Sm-like protein LSm11 GN=LSM11 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U7 snRNA-associated Sm-like protein LSm11 [Loxodonta africana]
ENSG00000155875(SAXO1)	--	0.032073556	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	STOP protein	Protein FAM154A GN=FAM154A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM154A [Oryctolagus cuniculus]
ENSG00000155876(RRAGA)	--	107.632	2723	95.8648	2470	89.0634	2290	73.8495	1881	64.3744	1623	77.5647	1966	0.125814855	-0.564143974	normal	0.03842015	-0.626797452	normal	0.965315193	-0.228212896	normal	0.00123855	-0.473398697	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K16185|0|ssc:100153321|RRAGA; Ras-related GTP binding A; K16185 Ras-related GTP-binding protein A/B (A)	mTOR signaling pathway (ko04150)	[T]	Signal transduction mechanisms	Gtr1/RagA G protein conserved region;; Ras family;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Miro-like protein	Ras-related GTP-binding protein A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ras-related GTP-binding protein A [Bison bison bison]
ENSG00000155886(SLC24A2)	--	0.005325503	1	0	0	0	0	0	0	0	0	0.00527374	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13750|0|ggo:101132958|SLC24A2; sodium/potassium/calcium exchanger 2; K13750 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Sodium/calcium exchanger protein	Sodium/potassium/calcium exchanger 2 GN=SLC24A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	sodium/potassium/calcium exchanger 2 [Sus scrofa]
ENSG00000155893(PXYLP1)	--	3.767432276	227	2.90294854	165	3.520576883	217	4.348316743	268	4.859809931	289	2.916643516	186	0.944823492	0.207415326	normal	0.022997861	0.781697043	normal	0.941335406	-0.228958585	normal	0.493756328	0.265097335	normal	--	--	Molecular Function: acid phosphatase activity (GO:0003993);; 	--	--	[R]	General function prediction only	Histidine phosphatase superfamily (branch 2)	2-phosphoxylose phosphatase 1 {ECO:0000303|PubMed:24425863} GN=UNQ370/PRO706 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: acid phosphatase-like protein 2 isoform X1 [Pteropus alecto] 
ENSG00000155897(ADCY8)	--	0.079359622	1	0	0	0.092937952	4	0.018775983	1	0	0	0.082439205	5	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: adenylate cyclase activity (GO:0004016);; Cellular Component: plasma membrane (GO:0005886);; Biological Process: cAMP biosynthetic process (GO:0006171);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	K08048|0|nle:100592592|ADCY8; adenylate cyclase 8 (brain); K08048 adenylate cyclase 8 [EC:4.6.1.1] (A)	Purine metabolism (ko00230);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; GABAergic synapse (ko04727);; Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Morphine addiction (ko05032);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[C]	Energy production and conversion	Adenylate and Guanylate cyclase catalytic domain;; Domain of Unknown Function (DUF1053)	Adenylate cyclase type 8 GN=ADCY8 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: adenylate cyclase type 8 isoform 1 [Odobenus rosmarus divergens]
ENSG00000155903(RASA2)	--	4.237414217	389	4.284259029	388	4.154708666	372	8.010444622	742	7.007339874	643	7.01537291	647	8.92E-05	0.898206452	normal	0.015584288	0.705179193	normal	0.002045984	0.787713214	normal	2.88E-06	0.800794014	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; Biological Process: regulation of GTPase activity (GO:0043087);; 	K08053|0|ptr:460741|RASA2; RAS p21 protein activator 2; K08053 Ras GTPase-activating protein 2 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Viral carcinogenesis (ko05203)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; C2 domain;; BTK motif;; PH domain	Ras GTPase-activating protein 2 GN=RASA2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating protein 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000155906(RMND1)	--	6.7732026	227	7.3338531	245	7.625556439	251	6.6685764	226	6.43434287	222	6.226142951	215	0.966463668	-0.036951134	normal	0.953734741	-0.162593764	normal	0.938787953	-0.230142345	normal	0.69475287	-0.146224347	normal	--	--	--	--	--	[S]	Function unknown	"Uncharacterised ACR, YagE family COG1723"	Required for meiotic nuclear division protein 1 homolog (Precursor) GN=RMND1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: required for meiotic nuclear division protein 1 homolog [Trichechus manatus latirostris]
ENSG00000155918(RAET1L)	--	0	0	0	0	0	0	0.086288606	1	0.217335164	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07987|1.60078e-154|hsa:154064|RAET1L, ULBP6; retinoic acid early transcript 1L; K07987 retinoic acid early transcript 1 (A)"	Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2"	Retinoic acid early transcript 1L protein (Precursor) GN=RAET1L OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: NKG2D ligand 1-like [Equus caballus]
ENSG00000155926(SLA)	--	0.031719546	2	0	0	0.026396707	0	0.031956722	2	0.06263861	3	0.079857828	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SH2 domain;; SH3 domain	Src-like-adapter GN=SLA OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: src-like-adapter isoform X1 [Galeopterus variegatus]
ENSG00000155957(TMBIM4)	--	37.40155136	504	34.60290831	505	28.9571531	444	54.340561	753	36.50325018	654	34.69841444	567	0.203298306	0.547021432	normal	0.83118884	0.350655698	normal	0.840933967	0.343459966	normal	0.024744671	0.419810235	normal	[R]	General function prediction only	--	"K06890|3.64222e-150|hsa:51643|TMBIM4, GAAP, LFG4, S1R, ZPRO; transmembrane BAX inhibitor motif containing 4; K06890 (A)"	--	[T]	Signal transduction mechanisms	Inhibitor of apoptosis-promoting Bax1	Protein lifeguard 4 GN=TMBIM4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	Transmembrane BAX inhibitor motif-containing protein 4 [Bos mutus]
ENSG00000155959(VBP1)	--	40.44401	1008	44.87851016	1094	39.82401	990	40.99495	1026	38.38073	953	32.5332689	823	0.979733541	-0.005289181	normal	0.952195809	-0.220164786	normal	0.921172776	-0.274367172	normal	0.432973051	-0.16404042	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prefoldin subunit;; Prefoldin subunit	Prefoldin subunit 3 GN=VBP1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prefoldin subunit 3 [Equus caballus]
ENSG00000155961(RAB39B)	--	1.66021	102	1.98267	123	1.6903	103	0.177601	11	0.189287	11	0.35431	22	1.67E-13	-3.074650334	down	0	-3.334872558	down	2.16E-08	-2.160150537	down	5.86E-13	-2.917397281	down	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07925|9.57357e-146|tup:102501152|RAB39B; RAB39B, member RAS oncogene family; K07925 Ras-related protein Rab-39B (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-39B GN=RAB39B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	ras-related protein Rab-39B [Bos taurus] 
ENSG00000155962(CLIC2)	--	0.110728975	5	0.089357259	4	0	0	0.153148311	7	0.0213809	0	0.109202155	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K05022|0|ptr:741540|CLIC2; chloride intracellular channel 2; K05022 chloride intracellular channel protein 2 (A)	--	[P]	Inorganic ion transport and metabolism	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutaredoxin"	Chloride intracellular channel protein 2 GN=CLIC2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: chloride intracellular channel protein 2 [Loxodonta africana]
ENSG00000155970(MICU3)	--	5.11190517	460	3.772697777	338	4.302767869	372	3.611517099	328	3.948820514	352	3.706614648	360	0.380116346	-0.516715571	normal	0.967133235	0.036963563	normal	0.967743584	-0.055368335	normal	0.495619638	-0.190874304	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[P]	Inorganic ion transport and metabolism	EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair	"Calcium uptake protein 3, mitochondrial GN=MICU3 OS=Homo sapiens (Human) PE=2 SV=1"	P	Inorganic ion transport and metabolism	PREDICTED: EF-hand domain-containing family member A2 [Sorex araneus]
ENSG00000155974(GRIP1)	--	1.935544629	105	1.397768935	112	2.410420158	135	1.61493339	89	1.207573113	91	1.898217128	132	0.951755028	-0.265124729	normal	0.935555639	-0.316240273	normal	0.968037644	-0.040256848	normal	0.701627286	-0.193652699	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Tricorn protease PDZ domain	Glutamate receptor-interacting protein 1 GN=GRIP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: glutamate receptor-interacting protein 1 [Tupaia chinensis]
ENSG00000155975(VPS37A)	--	16.71798	794	18.75674	764	19.79859	832	19.049776	928	19.556294	862	17.99149667	802	0.957363166	0.193806388	normal	0.965461046	0.15240454	normal	0.975752874	-0.061159499	normal	0.704308168	0.095550103	normal	--	--	--	K12185|0|pon:100431650|VPS37A; vacuolar protein sorting 37 homolog A (S. cerevisiae); K12185 ESCRT-I complex subunit VPS37 (A)	Endocytosis (ko04144)	[S]	Function unknown	Modifier of rudimentary (Mod(r)) protein	Vacuolar protein sorting-associated protein 37A GN=VPS37A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 37A isoform X1 [Galeopterus variegatus]
ENSG00000155980(KIF5A)	--	0.970607951	127	0.605953671	81	0.690493775	91	0.225080592	31	0.364053957	47	0.151614263	20	5.35E-09	-2.011967979	down	0.542564349	-0.787155007	normal	2.75E-07	-2.112416262	down	0.000122844	-1.631314454	down	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10396|0|mcf:101865454|Neuronal kinesin heavy chain; K10396 kinesin family member 5 (A)	Dopaminergic synapse (ko04728)	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin heavy chain isoform 5A GN=KIF5A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin heavy chain isoform 5A [Galeopterus variegatus]
ENSG00000156009(MAGEA8)	--	0	0	0.030910251	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 8 GN=MAGEA8 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: putative MAGE domain-containing protein MAGEA13P-like [Ceratotherium simum simum]
ENSG00000156011(PSD3)	--	8.833072617	1501	6.779081084	1098	8.932302921	1294	8.119497558	1381	8.885240379	1600	5.048088502	869	0.974842544	-0.150881838	normal	0.272875682	0.521169433	normal	0.089751284	-0.581865532	normal	0.958484282	-0.038186064	normal	[R]	General function prediction only	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	"K12494|0|hsa:23362|PSD3, EFA6D, EFA6R, HCA67; pleckstrin and Sec7 domain containing 3; K12494 PH and SEC7 domain-containing protein (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; Pleckstrin homology domain;; PH domain	PH and SEC7 domain-containing protein 3 GN=PSD3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PH and SEC7 domain-containing protein 3 [Loxodonta africana]
ENSG00000156017(CARNMT1)	--	12.8134	660	13.28676	730	12.82928738	698	15.516793	865	12.922895	702	13.86956	734	0.813462786	0.358670645	normal	0.972510165	-0.077687857	normal	0.97400291	0.064126088	normal	0.629099757	0.118356052	normal	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	N2227-like protein	UPF0586 protein C9orf41 GN=C9orf41 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: UPF0586 protein C9orf41 homolog [Bison bison bison]
ENSG00000156026(MCU)	--	21.22396729	1044	27.98931349	1372	23.00331709	1113	33.52012745	1652	35.24356358	1718	36.70122219	1799	0.030264338	0.630516189	normal	0.916293966	0.302724268	normal	0.008169758	0.683712588	normal	0.000282319	0.529496663	normal	--	--	--	--	--	[R]	General function prediction only	"Protein of unknown function, DUF607"	"Calcium uniporter protein, mitochondrial (Precursor) GN=MCU OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: calcium uniporter protein, mitochondrial isoform X2 [Mustela putorius furo]"
ENSG00000156030(ELMSAN1)	--	9.008197265	1406	9.40295471	1483	10.47941091	1661	7.79822675	1208	6.557589066	1014	7.178184009	1120	0.945175292	-0.249513885	normal	0.125686669	-0.569181028	normal	0.0959634	-0.576201657	normal	0.001962475	-0.466402972	normal	--	--	--	--	--	--	--	ELM2 domain	ELM2 and SANT domain-containing protein 1 GN=ELMSAN1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ELM2 and SANT domain-containing protein 1 [Galeopterus variegatus]
ENSG00000156042(CFAP70)	--	0.261285412	20	0.246117812	10	0.189259686	13	0.230456653	16	0.22398301	16	0.136042583	10	0.987479158	-0.32480531	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 18 GN=TTC18 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 18 isoform X1 [Equus caballus] 
ENSG00000156049(GNA14)	--	0.0245402	1	0.0242866	1	0	0	0.0242828	1	0.0237496	0	0.024334	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04636|0|hsa:9630|GNA14; guanine nucleotide binding protein (G protein), alpha 14; K04636 guanine nucleotide-binding protein subunit alpha-14 (A)"	Calcium signaling pathway (ko04020);; Chagas disease (American trypanosomiasis) (ko05142);; Amoebiasis (ko05146)	[T]	Signal transduction mechanisms	G-protein alpha subunit;; ADP-ribosylation factor family	Guanine nucleotide-binding protein subunit alpha-14 GN=GNA14 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit alpha-14 [Ceratotherium simum simum]
ENSG00000156050(FAM161B)	--	6.611250043	233	6.305898	205	8.04619	299	8.11719	296	9.586158	315	9.166885	297	0.893525474	0.312602559	normal	0.261365722	0.59473696	normal	0.967713784	-0.017883241	normal	0.323280127	0.280490452	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0564	Protein FAM161B GN=FAM161B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM161B [Galeopterus variegatus]
ENSG00000156052(GNAQ)	--	16.81016004	1593	20.88397656	1912	19.45218007	1701	20.16552063	1864	19.25755336	1746	16.84782377	1715	0.969704151	0.195648755	normal	0.977854146	-0.152329385	normal	0.985386593	0.003530867	normal	0.974092614	0.01106124	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: GTP binding (GO:0005525);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: guanyl nucleotide binding (GO:0019001);; Molecular Function: G-protein beta/gamma-subunit complex binding (GO:0031683);; 	"K04634|0|ssc:654405|GNAQ; guanine nucleotide binding protein (G protein), q polypeptide; K04634 guanine nucleotide-binding protein G(q) subunit alpha (A)"	Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Huntington's disease (ko05016);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	G-protein alpha subunit;; ADP-ribosylation factor family	Guanine nucleotide-binding protein G(q) subunit alpha GN=GNAQ OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(q) subunit alpha [Trichechus manatus latirostris] 
ENSG00000156076(WIF1)	--	0.142683651	5	0	0	0.028759598	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K01691|0|hsa:11197|WIF1, WIF-1; WNT inhibitory factor 1; K01691 WNT inhibitory factor 1 (A)"	Wnt signaling pathway (ko04310)	[TW]	Signal transduction mechanisms;; Extracellular structures	WIF domain;; EGF-like domain;; EGF-like domain;; Human growth factor-like EGF	Wnt inhibitory factor 1 (Precursor) GN=WIF1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: wnt inhibitory factor 1 [Trichechus manatus latirostris]
ENSG00000156097(GPR61)	--	0.030029592	2	0	0	0	0	0.029918942	2	0.014658102	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08414|0|ptr:100615011|GPR61; G protein-coupled receptor 61; K08414 G protein-coupled receptor 61 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 61 GN=GPR61 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 61 [Galeopterus variegatus]
ENSG00000156103(MMP16)	--	3.178477	403	4.90966	333	2.682383086	469	1.451724831	262	1.685370435	302	1.57429	209	0.080323728	-0.648950965	normal	0.953863702	-0.161629026	normal	3.05E-07	-1.168576286	down	0.009560128	-0.66169087	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	K07996|0|ptr:736322|MMP16; matrix metallopeptidase 16 (membrane-inserted); K07996 matrix metalloproteinase-16 (membrane-inserted) [EC:3.4.24.-] (A)	MicroRNAs in cancer (ko05206)	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Domain of unknown function (DUF3377);; Putative peptidoglycan binding domain;; Astacin (Peptidase family M12A)	Matrix metalloproteinase-16 (Precursor) GN=MMP16 OS=Homo sapiens (Human) PE=1 SV=2	OW	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	PREDICTED: matrix metalloproteinase-16 [Oryctolagus cuniculus]
ENSG00000156110(ADK)	--	33.747924	892	32.55838703	875	39.44839831	1005	40.974225	1101	35.33563613	928	36.63980787	934	0.924525801	0.272443583	normal	0.976270676	0.063308977	normal	0.973867554	-0.113814788	normal	0.771863419	0.074624149	normal	[G]	Carbohydrate transport and metabolism	--	K00856|0|mcf:102134008|ADK; adenosine kinase; K00856 adenosine kinase [EC:2.7.1.20] (A)	Purine metabolism (ko00230)	[G]	Carbohydrate transport and metabolism	pfkB family carbohydrate kinase	Adenosine kinase GN=ADK OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: adenosine kinase isoform X1 [Oryctolagus cuniculus]
ENSG00000156113(KCNMA1)	--	26.37940455	1562	28.02737344	1507	28.31000161	1487	40.11217334	2456	30.06898279	1835	27.96456375	1531	0.036036073	0.621592475	normal	0.945989263	0.262435104	normal	0.983792185	0.033744371	normal	0.3207312	0.331016338	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04936|0|hgl:101726007|Kcnma1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; K04936 potassium large conductance calcium-activated channel subfamily M alpha member 1 (A)"	cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Insulin secretion (ko04911);; Salivary secretion (ko04970);; Pancreatic secretion (ko04972)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Calcium-activated BK potassium channel alpha subunit;; Ion transport protein;; Ion channel;; TrkA-N domain	Calcium-activated potassium channel subunit alpha-1 GN=KCNMA1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: calcium-activated potassium channel subunit alpha-1 isoform X1 [Erinaceus europaeus]
ENSG00000156136(DCK)	--	18.15972004	641	18.12881303	641	18.91334872	658	17.16281203	613	14.9870427	530	14.06881074	498	0.970024633	-0.09503657	normal	0.897587657	-0.29499186	normal	0.699096538	-0.409148755	normal	0.20869073	-0.263284677	normal	[F]	Nucleotide transport and metabolism	--	K00893|0|hsa:1633|DCK; deoxycytidine kinase (EC:2.7.1.74); K00893 deoxycitidine kinase [EC:2.7.1.74] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Deoxynucleoside kinase;; Putative binding domain;; AAA domain	Deoxycytidine kinase GN=DCK OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: deoxycytidine kinase [Lipotes vexillifer]
ENSG00000156140(ADAMTS3)	--	0.2220992	24	0.099179685	9	0.1879461	19	0	0	0	0	0.025089207	3	0.000264897	-4.069429567	down	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08619|0|hsa:9508|ADAMTS3, ADAMTS-4; ADAM metallopeptidase with thrombospondin type 1 motif, 3 (EC:3.4.24.-); K08619 a disintegrin and metalloproteinase with thrombospondin motifs 3 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin family propeptide;; ADAM-TS Spacer 1;; Thrombospondin type 1 domain;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 3 (Precursor) GN=ADAMTS3 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 3 [Orycteropus afer afer]
ENSG00000156150(ALX3)	--	0.755126	25	0.979245	33	0.433562	14	0.539357	18	0.761506	25	0.802342	27	0.980167777	-0.470534008	normal	0.974201962	-0.400795003	normal	0.93746089	0.870504945	normal	0.972775049	-0.061783174	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09323|0|hsa:257|ALX3, FND, FND1; ALX homeobox 3; K09323 homeobox protein aristaless-like 3 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein aristaless-like 3 GN=ALX3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein aristaless-like 3 [Odobenus rosmarus divergens]
ENSG00000156162(DPY19L4)	--	15.11253413	1104	12.26013984	968	14.90743524	1055	14.50176278	1151	13.3850475	1064	13.46708619	991	0.980620393	0.029275496	normal	0.97388891	0.1148215	normal	0.976041234	-0.098431869	normal	0.967377887	0.014409841	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Q-cell neuroblast polarisation	Probable C-mannosyltransferase DPY19L4 GN=DPY19L4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein dpy-19 homolog 4 [Mustela putorius furo]
ENSG00000156170(NDUFAF6)	--	8.811532	305	9.64723	342	8.4211552	299	9.367559	304	8.18856	258	8.86077	303	0.967340841	-0.035391605	normal	0.725702252	-0.425875817	normal	0.967848499	0.010826472	normal	0.640868972	-0.150577421	normal	[I]	Lipid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: transferase activity (GO:0016740);; 	"K18163|0|pps:100982455|NDUFAF6; NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; K18163 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 6 (A)"	--	[I]	Lipid transport and metabolism	Squalene/phytoene synthase	"NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 (Precursor) GN=NDUFAF6 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 [Pteropus alecto]"
ENSG00000156171(DRAM2)	--	11.2079916	282	10.719558	269	11.043191	271	15.55502	397	15.432646	391	14.152973	359	0.608243669	0.460488128	normal	0.44253609	0.515718296	normal	0.779711389	0.395476104	normal	0.044198058	0.459164296	normal	--	--	--	--	--	[S]	Function unknown	Frag1/DRAM/Sfk1 family	DNA damage-regulated autophagy modulator protein 2 GN=DRAM2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DNA damage-regulated autophagy modulator protein 2 [Loxodonta africana]
ENSG00000156172(C8orf37)	--	6.774249	406	7.978614	451	7.435122	404	3.265482316	185	4.025934	232	4.21979	251	9.40E-07	-1.15811858	down	8.03E-05	-0.975779868	normal	0.040297361	-0.691643189	normal	3.38E-06	-0.937022944	normal	--	--	--	--	--	--	--	Retinal Maintenance	Protein C8orf37 GN=C8orf37 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein C8orf37 homolog isoform X1 [Galeopterus variegatus]
ENSG00000156194(PPEF2)	--	0	0	0	0	0	0	0	0	0	0	0.0150458	1	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Molecular Function: hydrolase activity (GO:0016787);; 	"K13807|0|hsa:5470|PPEF2, PPP7CB; protein phosphatase, EF-hand calcium binding domain 2 (EC:3.1.3.16); K13807 serine/threonine-protein phosphatase with EF-hands [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Calcineurin-like phosphoesterase;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF-hand domain pair;; EF hand;; PPP5 TPR repeat region	Serine/threonine-protein phosphatase with EF-hands 2 GN=PPEF2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase with EF-hands 2 [Loxodonta africana]
ENSG00000156218(ADAMTSL3)	--	0.020343734	3	0	0	0.020062005	2	0.027134096	4	0.052726404	7	0.026988834	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: peptidase activity (GO:0008233);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thrombospondin type 1 domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; PLAC (protease and lacunin) domain	ADAMTS-like protein 3 (Precursor) GN=ADAMTSL3 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ADAMTS-like protein 3 [Ceratotherium simum simum]
ENSG00000156222(SLC28A1)	--	0.02200775	1	0	0	0.027040243	0	0.111118438	4	0.171704648	7	0.135496004	5	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	--	K11536|0|ggo:101123963|SLC28A1; sodium/nucleoside cotransporter 1 isoform 1; K11536 pyrimidine nucleoside transport protein (A)	--	[FP]	Nucleotide transport and metabolism;; Inorganic ion transport and metabolism	Na+ dependent nucleoside transporter C-terminus;; Na+ dependent nucleoside transporter N-terminus;; Nucleoside recognition	Sodium/nucleoside cotransporter 1 GN=SLC28A1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/nucleoside cotransporter 1 isoform X1 [Galeopterus variegatus]
ENSG00000156232(WHAMM)	--	3.136468041	290	3.813499787	356	3.372713743	314	4.201681722	389	3.768514822	350	4.43361709	413	0.780161724	0.391090528	normal	0.96697519	-0.045752857	normal	0.785440476	0.38546223	normal	0.362091914	0.241881082	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	--	--	--	--	--	"WASP homolog-associated protein with actin, membranes and microtubules GN=WHAMM OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: WASP homolog-associated protein with actin, membranes and microtubules [Lipotes vexillifer]"
ENSG00000156239(N6AMT1)	--	3.435934902	185	3.44078856	202	3.819013199	192	2.454912429	144	3.01309839	204	3.12152123	183	0.861228139	-0.38861952	normal	0.965801461	-0.007159364	normal	0.96492968	-0.076933346	normal	0.726971437	-0.145281535	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; 	"K02493|4.60783e-143|hsa:29104|N6AMT1, C21orf127, HEMK2, MTQ2, N6AMT, m.HsaHemK2P; N-6 adenine-specific DNA methyltransferase 1 (putative) (EC:2.1.1.72); K02493 release factor glutamine methyltransferase [EC:2.1.1.297] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Methyltransferase domain;; Methyltransferase small domain;; Methyltransferase domain;; Ribosomal protein L11 methyltransferase (PrmA)	HemK methyltransferase family member 2 GN=N6AMT1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: hemK methyltransferase family member 2-like isoform X1 [Pantholops hodgsonii]
ENSG00000156253(RWDD2B)	--	5.780336	288	3.852069135	190	4.589143656	224	4.807146974	239	3.946512595	196	4.330058433	215	0.903792749	-0.298141409	normal	0.965653272	0.023245514	normal	0.965243404	-0.066991825	normal	0.731740104	-0.132652424	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Protein of unknown function (DUF1115);; RWD domain	RWD domain-containing protein 2B GN=RWDD2B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: RWD domain-containing protein 2B [Odobenus rosmarus divergens]
ENSG00000156256(USP16)	--	11.40203878	687	13.12860337	818	11.00577823	655	10.87605776	661	11.77556879	723	11.83234874	743	0.971656991	-0.086295314	normal	0.953749727	-0.199139849	normal	0.95954024	0.173200174	normal	0.890128429	-0.043308267	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11844|0|hsa:10600|USP16, UBP-M, UBPM; ubiquitin specific peptidase 16 (EC:3.4.19.12); K11844 ubiquitin carboxyl-terminal hydrolase 16/45 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 16 {ECO:0000255|HAMAP-Rule:MF_03062} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 16 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000156261(CCT8)	--	117.7876537	3800	113.5320603	3721	123.6320726	3980	114.5623789	3770	104.0169975	3335	93.34719104	3013	0.99152551	-0.042250008	normal	0.98321645	-0.179353144	normal	0.78408735	-0.409679688	normal	0.259034915	-0.206607259	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09500|0|pon:100172606|CCT8; chaperonin containing TCP1, subunit 8 (theta); K09500 T-complex protein 1 subunit theta (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit theta GN=CCT8 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: T-complex protein 1 subunit theta [Pteropus alecto]
ENSG00000156265(MAP3K7CL)	--	1.198288523	43	0.764642159	34	0.845202558	25	0.846209036	38	1.764346254	48	0.930280379	41	0.978445029	-0.201504486	normal	0.954299449	0.458825191	normal	0.926948451	0.673311235	normal	0.696661854	0.294736332	normal	--	--	--	--	--	--	--	--	MAP3K7 C-terminal-like protein GN=MAP3K7CL OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MAP3K7 C-terminal-like protein isoform X2 [Oryctolagus cuniculus] 
ENSG00000156273(BACH1)	--	7.650912839	565	6.686952313	615	7.422479529	611	7.557236	707	5.958473776	524	9.549547089	862	0.900024953	0.291916252	normal	0.927335585	-0.2517746	normal	0.401990562	0.487203974	normal	0.600550124	0.204160704	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09042|0|hsa:571|BACH1, BACH-1, BTBD24; BTB and CNC homology 1, basic leucine zipper transcription factor 1; K09042 transcription regulator BACH (A)"	--	[K]	Transcription	BTB/POZ domain;; bZIP Maf transcription factor;; bZIP transcription factor;; Basic region leucine zipper	Transcription regulator protein BACH1 GN=BACH1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription regulator protein BACH1-like [Tupaia chinensis]
ENSG00000156299(TIAM1)	--	0.289817085	35	0.18492158	19	0.28089698	36	0.77820017	114	0.974069	135	0.56533513	81	1.15E-05	1.630960045	up	4.29E-14	2.713952529	up	0.059106773	1.129197394	normal	5.47E-06	1.853186336	up	--	--	Molecular Function: receptor signaling protein activity (GO:0005057);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K05731|0|hsa:7074|TIAM1; T-cell lymphoma invasion and metastasis 1; K05731 T-lymphoma invasion and metastasis-inducing protein 1 (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Regulation of actin cytoskeleton (ko04810);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; Raf-like Ras-binding domain;; Pleckstrin homology domain;; PDZ domain (Also known as DHR or GLGF)	T-lymphoma invasion and metastasis-inducing protein 1 GN=TIAM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: T-lymphoma invasion and metastasis-inducing protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000156304(SCAF4)	--	9.243736	793	10.220878	874	8.948672701	767	8.843176194	753	9.663811344	831	8.533837725	737	0.971641011	-0.105293869	normal	0.973490843	-0.094044453	normal	0.974503667	-0.065721197	normal	0.727453367	-0.089942709	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13167|0|lve:103076402|SCAF4; SR-related CTD-associated factor 4; K13167 splicing factor, arginine/serine-rich 15 (A)"	--	[AK]	RNA processing and modification;; Transcription	"RNA polymerase II-binding domain.;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	"Splicing factor, arginine/serine-rich 15 GN=SCAF4 OS=Homo sapiens (Human) PE=1 SV=3"	A	RNA processing and modification	"PREDICTED: LOW QUALITY PROTEIN: splicing factor, arginine/serine-rich 15 [Lipotes vexillifer]"
ENSG00000156313(RPGR)	--	5.8831182	351	5.50549078	366	5.823021278	334	3.655138795	246	4.90908212	281	3.884770479	251	0.370790236	-0.540800793	normal	0.768845417	-0.400803993	normal	0.74308871	-0.418259937	normal	0.053660268	-0.455118033	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	--	--	--	[S]	Function unknown	"Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat;; Galactose oxidase, central domain"	X-linked retinitis pigmentosa GTPase regulator (Precursor) GN=RPGR OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: X-linked retinitis pigmentosa GTPase regulator isoform 1 [Ceratotherium simum simum]
ENSG00000156345(CDK20)	--	4.539511301	178	3.78174259	148	4.156514454	160	3.10976482	127	3.89797605	152	4.4371466	163	0.688772387	-0.512615216	normal	0.966488383	0.016877422	normal	0.967404079	0.018336902	normal	0.725513278	-0.157318746	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08817|0|hsa:23552|CDK20, CCRK, CDCH, P42, PNQALRE; cyclin-dependent kinase 20 (EC:2.7.11.22); K08817 cell cycle related kinase [EC:2.7.11.22] (A)"	--	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 20 GN=CDK20 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 20-like isoform 1 [Dasypus novemcinctus]
ENSG00000156374(PCGF6)	--	7.356307403	254	7.064373	247	6.897211254	243	9.162541116	327	10.07234236	354	6.086974389	214	0.872844832	0.331856833	normal	0.5348006	0.495266441	normal	0.94968903	-0.190373549	normal	0.513298746	0.244333892	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K11470|0|ptr:450710|PCGF6; polycomb group ring finger 6; K11470 polycomb group RING finger protein 6 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[S]	Function unknown	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	Polycomb group RING finger protein 6 GN=PCGF6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polycomb group RING finger protein 6 isoform X1 [Mustela putorius furo]
ENSG00000156381(ANKRD9)	--	36.18698	1313	35.166618	1326	31.910953	1319	33.959927	1217	31.17224	1149	27.557332	1194	0.97438796	-0.140199544	normal	0.953500721	-0.227849094	normal	0.972714754	-0.151750218	normal	0.374552614	-0.174164608	normal	--	--	--	--	--	[R]	General function prediction only	Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 9 GN=ANKRD9 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 9 isoformX1 [Sus scrofa] 
ENSG00000156384(SFR1)	--	10.07322893	225	7.382492168	172	10.02511215	220	11.27705734	258	9.884725	221	6.125316942	139	0.954288567	0.165557499	normal	0.888367572	0.337586795	normal	0.207020916	-0.664908948	normal	0.984445003	-0.020318771	normal	--	--	--	--	--	--	--	Double-strand recombination repair protein	Swi5-dependent recombination DNA repair protein 1 homolog GN=SFR1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: swi5-dependent recombination DNA repair protein 1 homolog [Galeopterus variegatus]
ENSG00000156398(SFXN2)	--	1.168883266	114	1.168070358	82	1.357894844	95	1.902859896	142	1.621703968	112	1.067979807	109	0.937955142	0.282606763	normal	0.893865165	0.421698249	normal	0.961604624	0.187252499	normal	0.513913922	0.29689059	normal	--	--	Biological Process: ion transport (GO:0006811);; Molecular Function: ion transmembrane transporter activity (GO:0015075);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Tricarboxylate carrier	Sideroflexin-2 GN=SFXN2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sideroflexin-2 [Galeopterus variegatus]
ENSG00000156411(C14orf2)	--	143.5689782	960	158.935395	1064	148.7122294	981	157.1900363	1087	150.71112	983	163.3383307	1084	0.970027234	0.148190388	normal	0.971556823	-0.135461009	normal	0.972128471	0.135549416	normal	0.862636741	0.048498681	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; 	K18193|2.65342e-57|ggo:101151160|uncharacterized protein C14orf178-like; K18193 6.8 kDa mitochondrial proteolipid (A)	--	--	--	Mitochondrial proteolipid	6.8 kDa mitochondrial proteolipid GN=MP68 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: 6.8 kDa mitochondrial proteolipid [Galeopterus variegatus] 
ENSG00000156413(FUT6)	--	0	0	0	0	0.039092954	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: fucosyltransferase activity (GO:0008417);; Cellular Component: membrane (GO:0016020);; 	"K07634|0|hsa:2528|FUT6, FCT3A, FT1A, Fuc-TVI, FucT-VI; fucosyltransferase 6 (alpha (1,3) fucosyltransferase) (EC:2.4.1.65); K07634 galactoside alpha-1,3-fucosyltransferase 6 [EC:2.4.1.65] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Glycosyltransferase family 10 (fucosyltransferase)	"Alpha-(1,3)-fucosyltransferase 6 GN=FUT6 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	PREDICTED: galactoside 3(4)-L-fucosyltransferase-like [Canis lupus familiaris]
ENSG00000156427(FGF18)	--	0.104481	4	0	0	0.124378	4	0.051484	2	0.150189	5	0.101467	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|3.99475e-123|pon:100460498|FGF18; fibroblast growth factor 18; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 18 (Precursor) GN=FGF18 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 18 [Orcinus orca] 
ENSG00000156453(PCDH1)	--	0.7120463	67	0.277613154	23	0.587062593	47	1.773443753	152	1.705896624	162	0.893495146	75	0.001497428	1.133305106	up	4.44E-16	2.717155512	up	0.802454982	0.649260974	normal	0.022122322	1.483061097	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K16498|0|ptr:750154|PCDH1; protocadherin 1; K16498 protocadherin delta 1 (A)	--	--	--	Cadherin domain;; Protocadherin;; Cadherin-like	Protocadherin-1 (Precursor) GN=PCDH1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protocadherin-1 [Ceratotherium simum simum]
ENSG00000156463(SH3RF2)	--	2.618362	228	2.286398	201	2.989914	264	4.68748	461	4.62973	418	3.950303	364	5.74E-05	0.980165834	normal	3.39E-05	1.029395676	up	0.646244874	0.4528906	normal	6.14E-05	0.821413648	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K12171|0|hsa:153769|SH3RF2, HEPP1, POSHER, PPP1R39, RNF158; SH3 domain containing ring finger 2; K12171 E3 ubiquitin-protein ligase SH3RF [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; RING-type zinc-finger;; Ring finger domain"	Putative E3 ubiquitin-protein ligase SH3RF2 GN=SH3RF2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	Putative E3 ubiquitin-protein ligase SH3RF2 [Tupaia chinensis]
ENSG00000156466(GDF6)	--	0.337349248	12	0.104057188	7	0.156507019	1	0.254947808	17	0.528765159	35	0.354450187	20	--	--	--	0.016883996	2.081684562	normal	0.026972074	3.092584572	normal	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04664|0|hsa:392255|GDF6, BMP-13, BMP13, CDMP2, KFM, KFS, KFS1, KFSL, LCA17, MCOP4, MCOPCB6, SCDO4, SGM1; growth differentiation factor 6; K04664 growth differentiation factor 5/6/7 (A)"	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain;; TGF-beta propeptide	Growth/differentiation factor 6 (Precursor) GN=GDF6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: growth/differentiation factor 6 [Odobenus rosmarus divergens]
ENSG00000156467(UQCRB)	--	59.66870785	1966	59.91789396	1947	65.75401495	2096	68.07197099	2347	67.79791866	2228	58.4050285	2127	0.96660002	0.224561478	normal	0.97690962	0.172944145	normal	0.987336837	0.012880649	normal	0.506902737	0.136105891	normal	--	--	"Cellular Component: mitochondrial respiratory chain complex III (GO:0005750);; Biological Process: mitochondrial electron transport, ubiquinol to cytochrome c (GO:0006122);; "	K00417|5.34696e-86|mcf:102117303|cytochrome b-c1 complex subunit 7-like; K00417 ubiquinol-cytochrome c reductase subunit 7 (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Ubiquinol-cytochrome C reductase complex 14kD subunit	Cytochrome b-c1 complex subunit 7 GN=UQCRB OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: cytochrome b-c1 complex subunit 7-like [Ochotona princeps]
ENSG00000156469(MTERF3)	--	16.57513101	389	15.430856	351	17.93004335	413	14.037849	325	12.83275079	304	13.3517475	316	0.903191918	-0.28891222	normal	0.9357389	-0.227770708	normal	0.770734977	-0.392859015	normal	0.212460794	-0.308083228	normal	--	--	"Molecular Function: double-stranded DNA binding (GO:0003690);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15032|0|ptr:464295|MTERF3, MTERFD1; mitochondrial transcription termination factor 3; K15032 mTERF domain-containing protein, mitochondrial (A)"	--	[KR]	Transcription;; General function prediction only	mTERF	"Transcription termination factor 3, mitochondrial (Precursor) GN=MTERF3 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: mTERF domain-containing protein 1, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000156471(PTDSS1)	--	37.73658493	2063	33.86141759	1928	33.404632	1880	44.17948931	2515	41.46472129	2152	34.883244	1919	0.957439758	0.254810222	normal	0.981008865	0.137044686	normal	0.986289643	0.021313638	normal	0.474005542	0.143676034	normal	--	--	Biological Process: phosphatidylserine biosynthetic process (GO:0006659);; 	K08729|0|ptr:464296|PTDSS1; phosphatidylserine synthase 1; K08729 phosphatidylserine synthase 1 [EC:2.7.8.-] (A)	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Phosphatidyl serine synthase	Phosphatidylserine synthase 1 GN=PTDSS1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: phosphatidylserine synthase 1 [Galeopterus variegatus]
ENSG00000156475(PPP2R2B)	--	0.437975864	21	0.087034925	5	0.534296249	21	0.291974387	12	0.444333882	20	0.234875128	11	0.97115279	-0.763441752	normal	0.689662297	1.705740547	normal	0.96332522	-0.854878976	normal	0.933325159	-0.14829806	normal	[T]	Signal transduction mechanisms	--	"K04354|0|ecb:100060957|PPP2R2B; protein phosphatase 2, regulatory subunit B, beta; K04354 serine/threonine-protein phosphatase 2A regulatory subunit B (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Dopaminergic synapse (ko04728);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	"WD domain, G-beta repeat"	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform GN=PPP2R2B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform 3 [Orcinus orca] 
ENSG00000156482(RPL30)	--	1161.467766	6532	1139.865852	6456	1077.209879	6341	1226.5767	7468	1156.57734	6566	1173.079701	6908	0.991299846	0.162329146	normal	0.994485163	0.002946929	normal	0.993049072	0.115239925	normal	0.695122811	0.094118144	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02908|7.6774e-79|tup:102501337|RPL30; ribosomal protein L30; K02908 large subunit ribosomal protein L30e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	60S ribosomal protein L30 GN=RPL30 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L30-like [Bubalus bubalis]
ENSG00000156486(KCNS2)	--	0.07017868	5	0.011710733	1	0	0	0.027897615	2	0.011614252	0	0.013939139	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04932|0|hsa:3788|KCNS2, KV9.2; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2; K04932 potassium voltage-gated channel delayed-rectifier subfamily S member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	BTB/POZ domain;; Ion transport protein;; Ion channel	Potassium voltage-gated channel subfamily S member 2 GN=KCNS2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily S member 2 [Camelus ferus] 
ENSG00000156500(FAM122C)	--	0.3108561	9	0.3620562	10	1.08899139	26	0.748126	18	0.602884664	13	0.4543099	11	--	--	--	--	--	--	0.861322568	-1.144293023	normal	--	--	--	--	--	--	--	--	--	--	--	Protein FAM122C GN=FAM122C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM122C-like [Vicugna pacos]
ENSG00000156502(SUPV3L1)	--	11.82440762	493	11.28140876	472	11.55730652	478	12.32921963	519	14.04839429	576	15.0204208	625	0.971020522	0.04318346	normal	0.918731036	0.265085488	normal	0.778830362	0.377506659	normal	0.307312415	0.232713394	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	"Molecular Function: hydrolase activity, acting on acid anhydrides (GO:0016817);; "	"K17675|0|pps:100969288|SUPV3L1; suppressor of var1, 3-like 1 (S. cerevisiae); K17675 ATP-dependent RNA helicase SUPV3L1/SUV3 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	Mitochondrial degradasome RNA helicase subunit C terminal;; Helicase conserved C-terminal domain	"ATP-dependent RNA helicase SUPV3L1, mitochondrial (Precursor) GN=SUPV3L1 OS=Homo sapiens (Human) PE=1 SV=1"	A	RNA processing and modification	"PREDICTED: ATP-dependent RNA helicase SUPV3L1, mitochondrial [Equus caballus]"
ENSG00000156504(FAM122B)	--	27.06275016	1555	29.58957198	1668	31.607749	1823	25.00362225	1474	22.017894	1283	22.5930267	1296	0.980219372	-0.107900794	normal	0.750477118	-0.399610261	normal	0.336662076	-0.50004584	normal	0.034875738	-0.337563876	normal	--	--	--	--	--	--	--	--	Protein FAM122B GN=FAM122B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM122B isoform X1 [Felis catus]
ENSG00000156508(EEF1A1)	--	4319.322268	184944	3534.546462	153931	3597.461759	154490	3505.123055	150394	3540.654313	149443	2872.21832	122071	0.996552547	-0.32917071	normal	0.999569539	-0.0641144	normal	0.994508733	-0.348080552	normal	0.386971333	-0.247603293	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K03231|0|tup:102493820|EEF1A1; eukaryotic translation elongation factor 1 alpha 1; K03231 elongation factor 1-alpha (A)	RNA transport (ko03013);; Legionellosis (ko05134)	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2	Elongation factor 1-alpha 1 GN=EEF1A1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: elongation factor 1-alpha 1 [Tupaia chinensis] 
ENSG00000156509(FBXO43)	--	3.370006619	160	3.841763274	165	3.956677723	174	2.482080425	133	2.25051539	108	2.636666372	123	0.928389076	-0.294372176	normal	0.449173847	-0.625717202	normal	0.716708327	-0.50348928	normal	0.162435332	-0.476502414	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10318|0|hsa:286151|FBXO43, EMI2, ERP1, FBX43; F-box protein 43; K10318 F-box protein 43 (A)"	Oocyte meiosis (ko04114)	--	--	IBR domain	F-box only protein 43 GN=FBXO43 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: F-box only protein 43 [Equus caballus]
ENSG00000156510(HKDC1)	--	17.25721098	1487	22.0584014	1947	22.32945332	1953	39.23637847	3405	36.79092538	3137	58.43995	5030	2.91E-10	1.16360168	up	0.015499254	0.666294746	normal	1.90E-14	1.355896443	up	0.005708685	1.083228486	up	[G]	Carbohydrate transport and metabolism	"Molecular Function: ATP binding (GO:0005524);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K00844|0|hsa:80201|HKDC1; hexokinase domain containing 1 (EC:2.7.1.1); K00844 hexokinase [EC:2.7.1.1] (A)	Glycolysis / Gluconeogenesis (ko00010);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520);; Butirosin and neomycin biosynthesis (ko00524);; Carbon metabolism (ko01200);; HIF-1 signaling pathway (ko04066);; Insulin signaling pathway (ko04910);; Type II diabetes mellitus (ko04930);; Carbohydrate digestion and absorption (ko04973);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Hexokinase;; Hexokinase	Putative hexokinase HKDC1 GN=HKDC1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: putative hexokinase HKDC1 [Equus caballus]
ENSG00000156515(HK1)	--	26.32713289	2083	20.88742592	1684	23.87264014	1910	31.25833931	2478	27.0121897	2105	26.62376378	2098	0.969122177	0.219532483	normal	0.926040946	0.300259931	normal	0.9820401	0.127054581	normal	0.230949028	0.213257685	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: ATP binding (GO:0005524);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K00844|0|pps:100969975|HK1; hexokinase 1; K00844 hexokinase [EC:2.7.1.1] (A)	Glycolysis / Gluconeogenesis (ko00010);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520);; Butirosin and neomycin biosynthesis (ko00524);; Carbon metabolism (ko01200);; HIF-1 signaling pathway (ko04066);; Insulin signaling pathway (ko04910);; Type II diabetes mellitus (ko04930);; Carbohydrate digestion and absorption (ko04973);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Hexokinase;; Hexokinase	Hexokinase-1 GN=HK1 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: hexokinase-1 isoform X1 [Oryctolagus cuniculus]
ENSG00000156531(PHF6)	--	19.83900909	1374	19.5884696	1346	21.8666473	1478	20.261463	1420	17.10490842	1184	17.2292726	1199	0.98320356	0.016658339	normal	0.961018846	-0.206188681	normal	0.902166838	-0.30975349	normal	0.408305774	-0.164175756	normal	--	--	--	--	--	[K]	Transcription	PHD-like zinc-binding domain;; PHD-zinc-finger like domain	PHD finger protein 6 GN=PHF6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: PHD finger protein 6 isoform X1 [Oryctolagus cuniculus] 
ENSG00000156535(CD109)	--	27.60443214	4018	30.382945	4387	29.43331	4173	34.4577008	5055	28.16703678	4081	34.47705946	5012	0.955391933	0.300298706	normal	0.989394991	-0.125693616	normal	0.972997042	0.255925312	normal	0.471714671	0.148351564	normal	--	--	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	K06530|0|ptr:462825|CD109; CD109 molecule; K06530 CD109 antigen (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; Alpha-2-macroglobulin family N-terminal region;; Alpha-2-macroglobulin family;; A-macroglobulin receptor;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region	CD109 antigen (Precursor) GN=CD109 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: CD109 antigen isoform 3 [Canis lupus familiaris]
ENSG00000156574(NODAL)	--	0.119601801	2	0.234739	6	0	0	0.219661937	7	0.250371264	7	0.058859793	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04666|0|hsa:4838|NODAL, HTX5; nodal growth differentiation factor; K04666 nodal (A)"	TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	--	--	Transforming growth factor beta like domain;; TGF-beta propeptide	Nodal homolog (Precursor) GN=NODAL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: nodal homolog [Galeopterus variegatus]
ENSG00000156587(UBE2L6)	--	23.69813559	596	16.60365627	425	19.74287838	507	28.40501572	722	33.17905336	834	29.0418385	738	0.93260518	0.245279076	normal	2.13E-05	0.948704555	normal	0.251903096	0.532020848	normal	0.000878258	0.565226067	normal	--	--	--	K04553|2.43234e-108|pps:100967273|UBE2L6; ubiquitin-conjugating enzyme E2L 6; K04553 ubiquitin-conjugating enzyme E2 L6 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; RWD domain	Ubiquitin/ISG15-conjugating enzyme E2 L6 GN=UBE2L6 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin/ISG15-conjugating enzyme E2 L6 isoform X3 [Tupaia chinensis]
ENSG00000156599(ZDHHC5)	--	35.62083135	2923	34.25049258	2978	34.36198	2990	40.09910356	3446	39.99224134	3448	40.13158092	3506	0.977890627	0.206540538	normal	0.980616388	0.189899779	normal	0.975259977	0.22128561	normal	0.259250666	0.205050182	normal	[R]	General function prediction only	--	"K18932|0|ptr:451199|ZDHHC5; zinc finger, DHHC-type containing 5 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC5 GN=ZDHHC5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC5 [Galeopterus variegatus] 
ENSG00000156603(MED19)	--	11.39819816	268	13.35956022	316	11.220678	269	14.25734	336	14.86858	351	14.8349433	351	0.903040951	0.293888673	normal	0.959367554	0.129531548	normal	0.81771186	0.373728937	normal	0.337790512	0.26196729	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15137|2.27138e-114|pps:100993175|MED19; mediator complex subunit 19; K15137 mediator of RNA polymerase II transcription subunit 19 (A)	--	[S]	Function unknown	Mediator of RNA pol II transcription subunit 19	Mediator of RNA polymerase II transcription subunit 19 GN=MED19 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 19 [Camelus bactrianus]
ENSG00000156639(ZFAND3)	--	44.16636496	1584	58.99048718	1675	39.71642568	1509	46.02706549	1581	39.87148017	1674	49.87921532	1645	0.984264821	-0.033534673	normal	0.984659681	-0.022268015	normal	0.980065336	0.116091875	normal	0.955958996	0.018203558	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	AN1-like Zinc finger;; A20-like zinc finger	AN1-type zinc finger protein 3 GN=ZFAND3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: AN1-type zinc finger protein 3 [Orcinus orca]
ENSG00000156642(NPTN)	--	161.852072	4282	173.09569	4589	153.526137	4017	145.068945	3657	131.9247479	3376	160.485704	4047	0.969351676	-0.258355991	normal	0.621487136	-0.464112376	normal	0.992198214	0.00244203	normal	0.174921106	-0.239185927	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Neuroplastin (Precursor) GN=NPTN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuroplastin isoform 1 [Odobenus rosmarus divergens]
ENSG00000156650(KAT6B)	--	3.751920159	716	4.692727904	892	4.096026493	769	2.690902085	506	2.873311054	553	3.56984848	697	0.256932408	-0.530293245	normal	0.008766337	-0.709647346	normal	0.964967244	-0.149806799	normal	0.032237774	-0.457203804	normal	[B]	Chromatin structure and dynamics	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K11306|0|pps:100988776|KAT6B; K(lysine) acetyltransferase 6B; K11306 histone acetyltransferase MYST4 [EC:2.3.1.48] (A)	--	[B]	Chromatin structure and dynamics	MOZ/SAS family;; PHD-finger;; linker histone H1 and H5 family	Histone acetyltransferase KAT6B GN=KAT6B OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase KAT6B [Galeopterus variegatus]
ENSG00000156671(SAMD8)	--	12.54932754	1191	11.63389071	1229	11.43768373	1094	10.89734896	1041	10.84800144	981	9.586592981	938	0.952213748	-0.224725215	normal	0.850667592	-0.34610861	normal	0.948328877	-0.229900776	normal	0.129676848	-0.269208907	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PAP2 superfamily C-terminal;; SAM domain (Sterile alpha motif)	Sphingomyelin synthase-related protein 1 GN=SAMD8 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: sphingomyelin synthase-related protein 1 [Pteropus alecto]
ENSG00000156675(RAB11FIP1)	--	7.956425447	1013	8.300746	1109	7.392412002	949	10.49601528	1361	10.637259	1378	9.094424001	1196	0.740907423	0.394682582	normal	0.918051671	0.291532726	normal	0.876397706	0.324983666	normal	0.040869722	0.33590843	normal	--	--	--	"K12484|0|hsa:80223|RAB11FIP1, NOEL1A, RCP, rab11-FIP1; RAB11 family interacting protein 1 (class I); K12484 Rab11 family-interacting protein 1/2/5 (A)"	Endocytosis (ko04144)	--	--	FIP domain;; C2 domain	Rab11 family-interacting protein 1 GN=RAB11FIP1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: rab11 family-interacting protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000156687(UNC5D)	--	4.218068826	668	3.826167238	580	3.161863711	462	1.957335913	304	3.175097364	453	2.590146557	423	4.13E-08	-1.162537388	down	0.78637071	-0.376853429	normal	0.961511243	-0.135064418	normal	0.067616867	-0.555832878	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K07521|0|hsa:137970|UNC5D, PRO34692, Unc5h4; unc-5 homolog D (C. elegans); K07521 netrin receptor unc-5 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	ZU5 domain;; Immunoglobulin I-set domain;; Thrombospondin type 1 domain;; Immunoglobulin domain;; Death domain;; Immunoglobulin domain	Netrin receptor UNC5D (Precursor) GN=UNC5D OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: netrin receptor UNC5D isoform X1 [Myotis lucifugus]
ENSG00000156689(GLYATL2)	--	0.24858389	6	0.041711768	1	0.124570211	2	0	0	0.040392723	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: mitochondrion (GO:0005739);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; Molecular Function: glycine N-acyltransferase activity (GO:0047961);; "	--	--	--	--	"Aralkyl acyl-CoA:amino acid N-acyltransferase;; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region;; FR47-like protein"	Glycine N-acyltransferase-like protein 2 GN=GLYATL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: glycine N-acyltransferase-like protein 2 [Galeopterus variegatus]
ENSG00000156697(UTP14A)	--	17.3432652	1138	18.75629936	1240	16.82507424	1114	18.90310066	1253	20.580251	1350	16.90618888	1117	0.977158269	0.107914714	normal	0.978404347	0.101074567	normal	0.980856662	-0.004405516	normal	0.781587836	0.069661876	normal	--	--	Biological Process: rRNA processing (GO:0006364);; Cellular Component: small-subunit processome (GO:0032040);; 	K14567|0|ggo:101142781|UTP14A; U3 small nucleolar RNA-associated protein 14 homolog A isoform 1; K14567 U3 small nucleolar RNA-associated protein 14 (A)	Ribosome biogenesis in eukaryotes (ko03008)	[S]	Function unknown	Utp14 protein	U3 small nucleolar RNA-associated protein 14 homolog A GN=UTP14A OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U3 small nucleolar RNA-associated protein 14 homolog A isoform 1 [Ceratotherium simum simum]
ENSG00000156709(AIFM1)	--	40.38115771	1831	42.36807694	1970	46.05837168	2081	44.27830746	2013	41.70138442	1866	45.77080751	2067	0.983201137	0.105798431	normal	0.983277863	-0.099594631	normal	0.987136509	-0.018016881	normal	0.987212077	-0.005382454	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: protein dimerization activity (GO:0046983);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K04727|0|pps:100991065|AIFM1; apoptosis-inducing factor, mitochondrion-associated, 1; K04727 programmed cell death 8 (apoptosis-inducing factor) [EC:1.-.-.-] (A)"	Apoptosis (ko04210)	[T]	Signal transduction mechanisms	"Apoptosis-inducing factor, mitochondrion-associated, C-term;; Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; Mitochondria Localisation Sequence"	"Apoptosis-inducing factor 1, mitochondrial (Precursor) GN=AIFM1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: apoptosis-inducing factor 1, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000156711(MAPK13)	--	0.251291606	31	0.330886326	21	0.182394166	21	0.162639293	14	0.369548471	25	0.145850395	18	0.813063661	-1.094978899	normal	0.985088018	0.215852711	normal	0.987784349	-0.214021374	normal	0.670957779	-0.377521806	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04441|0|hsa:5603|MAPK13, MAPK_13, MAPK-13, PRKM13, SAPK4, p38delta; mitogen-activated protein kinase 13 (EC:2.7.11.24); K04441 p38 MAP kinase [EC:2.7.11.24] (A)"	MAPK signaling pathway (ko04010);; Rap1 signaling pathway (ko04015);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Prolactin signaling pathway (ko04917);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Shigellosis (ko05131);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase 13 GN=MAPK13 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 13 [Ceratotherium simum simum]
ENSG00000156735(BAG4)	--	8.351570041	544	8.371022603	510	8.708500014	562	7.94079	522	9.296694217	607	7.118056207	455	0.968622395	-0.09012921	normal	0.937996676	0.229149237	normal	0.879907078	-0.312059959	normal	0.881859229	-0.050185952	normal	--	--	Molecular Function: chaperone binding (GO:0051087);; 	K09558|0|pps:100992629|BAG4; BCL2-associated athanogene 4; K09558 BCL2-associated athanogene 4 (A)	TNF signaling pathway (ko04668)	[T]	Signal transduction mechanisms	BAG domain	BAG family molecular chaperone regulator 4 GN=BAG4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: BAG family molecular chaperone regulator 4 isoform 2 [Ceratotherium simum simum]
ENSG00000156738(MS4A1)	--	0	0	0	0	0	0	0	0	0.023877669	0	0.067491112	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06466|0|hsa:931|MS4A1, B1, Bp35, CD20, CVID5, LEU-16, MS4A2, S7; membrane-spanning 4-domains, subfamily A, member 1; K06466 membrane-spanning 4-domains, subfamily A, member 1 (A)"	Hematopoietic cell lineage (ko04640)	--	--	CD20-like family	B-lymphocyte antigen CD20 GN=MS4A1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: B-lymphocyte antigen CD20 [Oryctolagus cuniculus]
ENSG00000156787(TBC1D31)	--	23.78866617	500	20.257479	439	22.32127222	456	24.0630711	457	18.87124965	412	24.7495241	474	0.95762483	-0.160051508	normal	0.963341479	-0.112602661	normal	0.970130414	0.047407577	normal	0.815138112	-0.075958257	normal	[R]	General function prediction only	--	--	--	[S]	Function unknown	"Rab-GTPase-TBC domain;; WD domain, G-beta repeat"	TBC1 domain family member 31 GN=TBC1D31 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: TBC1 domain family member 31 isoform X1 [Ailuropoda melanoleuca]
ENSG00000156795(WDYHV1)	--	18.75703372	316	13.35125701	269	15.07880026	275	10.61524363	221	14.18657803	286	11.33241618	207	0.395850565	-0.54353173	normal	0.964567145	0.06661917	normal	0.776422368	-0.415449887	normal	0.312281383	-0.289701163	normal	--	--	"Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811);; "	--	--	[S]	Function unknown	N-terminal glutamine amidase	Protein N-terminal glutamine amidohydrolase GN=WDYHV1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein N-terminal glutamine amidohydrolase isoform X3 [Galeopterus variegatus] 
ENSG00000156802(ATAD2)	--	22.08628356	2314	21.91830063	2284	25.27161604	2617	24.75730604	2627	22.52626005	2360	20.90009582	2182	0.982109785	0.152100248	normal	0.987720084	0.025780858	normal	0.951718747	-0.270382901	normal	0.91179757	-0.030751182	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; Bromodomain;; AAA ATPase domain;; IstB-like ATP binding protein;; AAA domain (Cdc48 subfamily)	ATPase family AAA domain-containing protein 2 GN=ATAD2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ATPase family AAA domain-containing protein 2 isoform 1 [Ceratotherium simum simum] 
ENSG00000156804(FBXO32)	--	2.668433835	98	2.922755981	115	3.698206196	127	12.19708736	788	12.79309939	784	17.917562	1116	0	2.957144369	up	0	2.73188483	up	0	3.112075426	up	3.61E-15	2.963059032	up	--	--	--	K10305|0|pps:100983214|FBXO32; F-box protein 32; K10305 F-box protein 25/32 (A)	FoxO signaling pathway (ko04068)	[E]	Amino acid transport and metabolism	--	F-box only protein 32 GN=FBXO32 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: F-box only protein 32 isoform 1 [Orcinus orca] 
ENSG00000156831(NSMCE2)	--	23.08786475	434	30.526674	574	28.28775	515	24.523648	480	24.689287	453	25.955959	480	0.964531487	0.114122842	normal	0.814002371	-0.361890193	normal	0.966057856	-0.10949634	normal	0.639329075	-0.12938668	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	Zinc-finger of the MIZ type in Nse subunit;; RING-type zinc-finger;; U-box domain	E3 SUMO-protein ligase NSE2 GN=NSMCE2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: E3 SUMO-protein ligase NSE2 isoform X2 [Oryctolagus cuniculus]
ENSG00000156853(ZNF689)	--	5.226433171	330	5.386594	338	5.041166482	324	4.793997587	305	5.409478592	339	5.178837937	326	0.957947105	-0.143792401	normal	0.967476325	-0.017088189	normal	0.968318367	0.000583992	normal	0.894142912	-0.053364535	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:467951|ZNF689; zinc finger protein 689; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 689 GN=ZNF689 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 689-like [Dasypus novemcinctus]
ENSG00000156858(PRR14)	--	12.14032782	554	10.77789973	482	12.628758	525	12.09819204	565	10.62626641	502	12.16839187	576	0.972894949	-0.002460615	normal	0.970270204	0.037113558	normal	0.965184369	0.125115763	normal	0.874673854	0.052729614	normal	--	--	--	--	--	--	--	Drosophila Tantalus-like	Proline-rich protein 14 GN=PRR14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: proline-rich protein 14 isoform X1 [Felis catus]
ENSG00000156860(FBRS)	--	20.74907	1750	21.18953	1809	20.73178	1807	23.28303	1883	20.99108	1745	20.72712	1761	0.984351578	0.074782514	normal	0.983844406	-0.073329508	normal	0.985235062	-0.045454503	normal	0.964068925	-0.015222317	normal	--	--	--	--	--	--	--	Autism susceptibility gene 2 protein	Probable fibrosin-1 GN=FBRS OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	"Putative fibrosin-1 long transcript protein, partial [Pteropus alecto]"
ENSG00000156869(FRRS1)	--	1.61984403	96	1.326131645	80	1.201875241	70	1.857875451	113	1.975641258	119	2.323346569	131	0.959736789	0.201410736	normal	0.771772196	0.542997423	normal	0.084345169	0.881706618	normal	0.170333942	0.540216952	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Reeler domain;; DOMON domain	Ferric-chelate reductase 1 GN=FRRS1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ferric-chelate reductase 1 [Ceratotherium simum simum]
ENSG00000156876(SASS6)	--	4.448087	278	5.413223116	334	5.243227	318	4.523883638	286	4.131601	259	4.105281	258	0.967487947	0.010043277	normal	0.802540442	-0.386330259	normal	0.893953734	-0.308316225	normal	0.423099788	-0.233327782	normal	--	--	--	K16487|0|pps:100971523|SASS6; spindle assembly 6 homolog (C. elegans); K16487 spindle assembly abnormal protein 6 (A)	--	--	--	--	Spindle assembly abnormal protein 6 homolog GN=SASS6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: spindle assembly abnormal protein 6 homolog isoform X1 [Galeopterus variegatus]
ENSG00000156886(ITGAD)	--	0.0117541	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06594|0|hsa:3681|ITGAD, ADB2, CD11D; integrin, alpha D; K06594 integrin alpha D (A)"	Regulation of actin cytoskeleton (ko04810)	[W]	Extracellular structures	Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; von Willebrand factor type A domain;; Integrin alpha cytoplasmic region	Integrin alpha-D (Precursor) GN=ITGAD OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin alpha-D [Galeopterus variegatus]
ENSG00000156928(MALSU1)	--	8.456741	408	8.50322	407	9.913235	469	8.805521	429	8.141543	393	8.13716	395	0.969302745	0.041424103	normal	0.966562163	-0.07165507	normal	0.923893467	-0.25512913	normal	0.755021989	-0.098522367	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Oligomerisation domain	Mitochondrial assembly of ribosomal large subunit protein 1 GN=MALSU1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: mitochondrial assembly of ribosomal large subunit 1 [Balaenoptera acutorostrata scammoni]
ENSG00000156931(VPS8)	--	7.831499633	677	8.840118331	731	8.076343126	698	7.206166143	632	8.039460294	700	9.293052716	785	0.966499459	-0.129758657	normal	0.972055232	-0.083765932	normal	0.96305455	0.160845397	normal	0.972572149	-0.013043833	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Golgi CORVET complex core vacuolar protein 8;; Region in Clathrin and VPS	Vacuolar protein sorting-associated protein 8 homolog GN=VPS8 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 8 homolog isoformX1 [Equus caballus] 
ENSG00000156958(GALK2)	--	14.85941124	521	11.44214792	415	13.35101114	494	12.40945398	498	12.44497078	439	13.93496506	544	0.967630059	-0.095681241	normal	0.967887645	0.059472322	normal	0.963778677	0.130423563	normal	0.940283296	0.029718252	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Molecular Function: galactose binding (GO:0005534);; 	K18674|0|ptr:744911|GALK2; galactokinase 2; K18674 N-acetylgalactosamine kinase [EC:2.7.1.157] (A)	--	[G]	Carbohydrate transport and metabolism	Galactokinase galactose-binding signature;; GHMP kinases N terminal domain;; GHMP kinases C terminal	N-acetylgalactosamine kinase GN=GALK2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: N-acetylgalactosamine kinase isoform 1 [Ceratotherium simum simum]
ENSG00000156959(LHFPL4)	--	0.0608269	6	0.0581819	6	0.115585	11	0.0503613	5	0.0496606	4	0.0603863	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Lipoma HMGIC fusion partner-like protein	Lipoma HMGIC fusion partner-like 4 protein GN=LHFPL4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: lipoma HMGIC fusion partner-like 4 protein [Tupaia chinensis]
ENSG00000156966(B3GNT7)	--	1.48545	105	1.41128	101	0.957798	69	0.543423	38	0.831894	58	0.352156	25	0.000205269	-1.460102148	down	0.338091528	-0.80553364	normal	0.01021591	-1.419179564	normal	0.003054937	-1.206921604	down	--	--	"Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K09664|0|hsa:93010|B3GNT7, beta3GnT7; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7; K09664 beta-1,3-N-acetylglucosaminyltransferase 7 [EC:2.4.1.-] (A)"	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase;; Fringe-like	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 GN=B3GNT7 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7 [Felis catus]"
ENSG00000156968(MPV17L)	--	42.602214	1881	38.754796	1772	37.123092	1835	27.42038643	1313	27.3358311	1296	24.312826	1088	0.158259378	-0.548925306	normal	0.482894212	-0.47226606	normal	0.000985121	-0.761568355	normal	3.50E-05	-0.591608589	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K13349|1.76368e-142|hsa:255027|MPV17L, M-LPH, MLPH1, MLPH2, MPV17L1; MPV17 mitochondrial membrane protein-like; K13349 Mpv17-like protein (A)"	Peroxisome (ko04146)	[R]	General function prediction only	Mpv17 / PMP22 family	Mpv17-like protein GN=MPV17L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mpv17-like protein [Odobenus rosmarus divergens]
ENSG00000156973(PDE6D)	--	23.01839	452	16.71022	327	20.97391	415	11.939451	241	13.72718	261	14.81698	286	0.000170021	-0.933699222	normal	0.858630362	-0.344877902	normal	0.320349837	-0.542990025	normal	0.00346563	-0.620020637	normal	--	--	--	"K13758|4.33703e-107|ptr:738319|PDE6D; phosphodiesterase 6D, cGMP-specific, rod, delta; K13758 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta (A)"	Purine metabolism (ko00230)	[T]	Signal transduction mechanisms	"GMP-PDE, delta subunit"	"Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta GN=PDE6D OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [Bos taurus] "
ENSG00000156976(EIF4A2)	--	76.13398855	2878	67.74340264	2632	76.47107571	2833	72.57644728	2830	73.89465328	2935	80.50594051	3071	0.989227668	-0.055067155	normal	0.9847781	0.135700595	normal	0.987477535	0.108031067	normal	0.804842596	0.061958742	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K03257|0|phd:102331535|EIF4A2; eukaryotic translation initiation factor 4A2; K03257 translation initiation factor 4A (A)	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Eukaryotic initiation factor 4A-II GN=EIF4A2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic initiation factor 4A-II isoform 1 [Dasypus novemcinctus] 
ENSG00000156983(BRPF1)	--	6.386749	707	5.36313759	598	5.16394219	575	5.469219	600	6.2965805	698	5.246242	582	0.919624773	-0.266949362	normal	0.950323833	0.201183703	normal	0.973326624	0.009141856	normal	0.95613985	-0.021372157	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11348|0|hsa:7862|BRPF1, BR140; bromodomain and PHD finger containing, 1; K11348 bromodomain and PHD finger-containing protein 1 (A)"	--	[R]	General function prediction only	PHD-zinc-finger like domain;; Enhancer of polycomb-like;; PHD-like zinc-binding domain;; Bromodomain;; PWWP domain;; PHD-finger;; PHD-finger	Peregrin GN=BRPF1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: peregrin isoform 2 [Odobenus rosmarus divergens]
ENSG00000156990(RPUSD3)	--	26.003809	554	27.424978	604	28.762164	632	25.562692	553	22.849983	485	21.622446	463	0.972298522	-0.033346196	normal	0.851165682	-0.337046493	normal	0.550796388	-0.45592389	normal	0.194954257	-0.275651416	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	--	--	[A]	RNA processing and modification	RNA pseudouridylate synthase	RNA pseudouridylate synthase domain-containing protein 3 GN=RPUSD3 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: RNA pseudouridylate synthase domain-containing protein 3 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000157014(TATDN2)	--	16.8941671	1663	17.17587	1646	17.6818	1690	17.107018	1673	23.52448	1964	15.92492	1578	0.984990561	-0.022162573	normal	0.960181837	0.233207676	normal	0.981246569	-0.107118263	normal	0.884831751	0.039813354	normal	[L]	"Replication, recombination and repair"	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	K03424|0|hsa:9797|TATDN2; TatD DNase domain containing 2; K03424 TatD DNase family protein [EC:3.1.21.-] (A)	--	[L]	"Replication, recombination and repair"	TatD related DNase	Putative deoxyribonuclease TATDN2 GN=TATDN2 OS=Homo sapiens (Human) PE=2 SV=2	L	"Replication, recombination and repair"	PREDICTED: putative deoxyribonuclease TATDN2 [Trichechus manatus latirostris]
ENSG00000157017(GHRL)	--	0	0	0	0	0.038104647	0	0.039172035	1	0.038019444	0	0.038432062	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05254|1.87062e-53|ptr:100609092|GHRL; appetite-regulating hormone; K05254 ghrelin (A)	cAMP signaling pathway (ko04024)	--	--	Motilin/ghrelin-associated peptide;; Motilin/ghrelin	Obestatin (Precursor) GN=GHRL OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: appetite-regulating hormone isoform X1 [Galeopterus variegatus]
ENSG00000157020(SEC13)	--	65.09053756	1735	59.49244322	1631	60.69114332	1664	73.86512096	1999	80.09938924	2119	67.67168869	1831	0.975317719	0.173367434	normal	0.86115288	0.355909998	normal	0.980103912	0.129572618	normal	0.212935694	0.220689269	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14004|0|hsa:6396|SEC13, D3S1231E, SEC13L1, SEC13R, npp-20; SEC13 homolog (S. cerevisiae); K14004 protein transport protein SEC13 (A)"	RNA transport (ko03013);; Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"WD domain, G-beta repeat"	Protein SEC13 homolog GN=SEC13 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein SEC13 homolog [Camelus ferus]
ENSG00000157036(EXOG)	--	6.786601918	677	7.45213266	715	34.8285499	622	8.805722307	706	9.27196865	784	8.01879003	665	0.974883498	0.029614273	normal	0.970094973	0.111259076	normal	0.971071706	0.0879415	normal	0.785812781	0.076124329	normal	[F]	Nucleotide transport and metabolism	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; 	"K15050|0|pps:100993303|EXOG; endo/exonuclease (5'-3'), endonuclease G-like; K15050 nuclease EXOG, mitochondrial (A)"	--	[F]	Nucleotide transport and metabolism	DNA/RNA non-specific endonuclease	"Nuclease EXOG, mitochondrial (Precursor) GN=EXOG OS=Homo sapiens (Human) PE=1 SV=2"	F	Nucleotide transport and metabolism	"PREDICTED: nuclease EXOG, mitochondrial isoform 1 [Equus caballus] "
ENSG00000157045(NTAN1)	--	29.852791	565	26.638825	514	32.770412	631	27.324374	526	27.843489	522	29.600359	565	0.96371106	-0.133643551	normal	0.971422777	0.000852401	normal	0.95876763	-0.167256721	normal	0.705814122	-0.104928496	normal	--	--	Molecular Function: protein-N-terminal asparagine amidohydrolase activity (GO:0008418);; 	K14662|0|mcf:102126239|NTAN1; N-terminal asparagine amidase; K14662 protein N-terminal asparagine amidohydrolase [EC:3.5.1.-] (A)	--	--	--	Protein N-terminal asparagine amidohydrolase	Protein N-terminal asparagine amidohydrolase GN=NTAN1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein N-terminal asparagine amidohydrolase isoform X1 [Vicugna pacos]
ENSG00000157064(NMNAT2)	--	0.57456246	67	0.555456167	65	0.5854451	67	0.803506296	91	0.939617	104	0.838745	93	0.925821583	0.402919432	normal	0.665888918	0.64468879	normal	0.899693209	0.456005548	normal	0.251882291	0.512274983	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; Biological Process: biosynthetic process (GO:0009058);; 	K06210|0|cfa:610576|NMNAT2; nicotinamide nucleotide adenylyltransferase 2; K06210 nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] (A)	Nicotinate and nicotinamide metabolism (ko00760)	[H]	Coenzyme transport and metabolism	Cytidylyltransferase	Nicotinamide mononucleotide adenylyltransferase 2 GN=NMNAT2 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: nicotinamide mononucleotide adenylyltransferase 2 isoform X6 [Canis lupus familiaris] 
ENSG00000157077(ZFYVE9)	--	4.703418951	494	5.72880555	574	4.798326001	497	4.978998626	529	4.723334	489	5.170788154	540	0.969877916	0.067720866	normal	0.926489339	-0.25192283	normal	0.966302123	0.111097721	normal	0.942531704	-0.027789987	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K04679|0|hsa:9372|ZFYVE9, MADHIP, NSP, PPP1R173, SARA, SMADIP; zinc finger, FYVE domain containing 9; K04679 MAD, mothers against decapentaplegic interacting protein (A)"	Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350)	[V]	Defense mechanisms	Domain of unknown function (DUF3480);; Smad anchor for receptor activation (SARA);; FYVE zinc finger	Zinc finger FYVE domain-containing protein 9 GN=ZFYVE9 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: zinc finger FYVE domain-containing protein 9 isoform X1 [Galeopterus variegatus]
ENSG00000157087(ATP2B2)	--	0	0	0	0	0.029218258	4	0	0	0.005754846	0	0.021932201	2	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: calcium-transporting ATPase activity (GO:0005388);; 	"K05850|0|mcf:101866950|uncharacterized LOC101866950; K05850 Ca2+ transporting ATPase, plasma membrane [EC:3.6.3.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Salivary secretion (ko04970);; Pancreatic secretion (ko04972)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; Plasma membrane calcium transporter ATPase C terminal;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; haloacid dehalogenase-like hydrolase;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase"	Plasma membrane calcium-transporting ATPase 2 GN=ATP2B2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: plasma membrane calcium-transporting ATPase 2 isoformX1 [Canis lupus familiaris] 
ENSG00000157106(SMG1)	--	20.324916	5806	23.46532807	6391	22.22952055	5758	18.5217688	5136	21.5940287	5500	21.47879301	5870	0.985055884	-0.207673153	normal	0.981472716	-0.237975857	normal	0.994109227	0.019496201	normal	0.505119527	-0.142294705	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	"Biological Process: nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: kinase activity (GO:0016301);; Biological Process: phosphorylation (GO:0016310);; "	"K08873|0|hsa:23049|SMG1, 61E3.4, ATX, LIP; SMG1 phosphatidylinositol 3-kinase-related kinase (EC:2.7.11.1); K08873 PI-3-kinase-related kinase SMG-1 (A)"	mRNA surveillance pathway (ko03015)	[L]	"Replication, recombination and repair"	Phosphatidylinositol 3- and 4-kinase;; FATC domain	Serine/threonine-protein kinase SMG1 GN=SMG1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	serine/threonine-protein kinase SMG1 [Bos taurus] 
ENSG00000157107(FCHO2)	--	7.044042121	588	8.352294912	688	7.471535751	580	8.692851674	731	7.216492122	604	8.712303476	730	0.90835621	0.282559766	normal	0.947806004	-0.208796329	normal	0.868265113	0.322800331	normal	0.591760296	0.132462907	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Muniscin C-terminal mu homology domain;; Fes/CIP4, and EFC/F-BAR homology domain"	FCH domain only protein 2 GN=FCHO2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: FCH domain only protein 2 isoform X1 [Myotis lucifugus]
ENSG00000157110(RBPMS)	--	46.2711335	1113	61.75792895	1260	57.4723055	1145	58.36466343	1361	53.74926533	1298	73.30972235	1702	0.938670253	0.25905739	normal	0.981769551	0.021414769	normal	0.123895207	0.562978243	normal	0.173728381	0.289265976	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein with multiple splicing GN=RBPMS OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein with multiple splicing isoform X1 [Loxodonta africana]
ENSG00000157111(TMEM171)	--	0.809885	18	0.930625	21	1.536988	32	1.100824	24	0.533310604	12	0.357680566	7	0.984670975	0.357696978	normal	0.96921607	-0.755948823	normal	0.049201327	-1.984439256	normal	0.351833094	-0.747498428	normal	--	--	--	--	--	--	--	Transmembrane protein family 171	Transmembrane protein 171 GN=TMEM171 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane protein 171 [Physeter catodon]
ENSG00000157150(TIMP4)	--	16.134579	796	13.58777005	764	13.69739555	716	10.54035057	507	15.40461834	751	10.491118	549	0.016025805	-0.67995523	normal	0.974903681	-0.04609426	normal	0.745329705	-0.390500088	normal	0.127467274	-0.353833464	normal	--	--	Molecular Function: metalloendopeptidase inhibitor activity (GO:0008191);; 	--	--	[R]	General function prediction only	Tissue inhibitor of metalloproteinase	Metalloproteinase inhibitor 4 (Precursor) GN=TIMP4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	metalloproteinase inhibitor 4 precursor [Oryctolagus cuniculus]
ENSG00000157152(SYN2)	--	0.1797772	11	0.040132	2	0.1409533	8	0.0598376	4	0.1372772	8	0.1598658	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Synapsin, ATP binding domain;; Synapsin, N-terminal domain;; Synapsin N-terminal;; RimK-like ATP-grasp domain"	Synapsin-2 GN=SYN2 OS=Homo sapiens (Human) PE=1 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synapsin-2 [Ceratotherium simum simum]
ENSG00000157168(NRG1)	--	65.11968379	3171	74.2288594	3705	76.06467371	3494	97.72934651	5279	119.1925852	6184	88.40086576	5069	0.004947901	0.704227443	normal	0.004835127	0.717411223	normal	0.294502197	0.528339195	normal	5.47E-06	0.651632153	normal	--	--	--	K05455|0|mcc:696275|NRG1; neuregulin 1; K05455 neuregulin 1 (A)	ErbB signaling pathway (ko04012)	--	--	Neuregulin family;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Neuregulin-1 (Precursor) GN=NRG1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: pro-neuregulin-2, membrane-bound isoform isoform 1 [Odobenus rosmarus divergens]"
ENSG00000157181(C1orf27)	--	8.993172697	572	8.848338	624	9.6309596	667	10.46342789	654	9.878966108	626	9.58749	671	0.960014363	0.162035981	normal	0.973393965	-0.016769354	normal	0.974974549	0.000333808	normal	0.888223748	0.045634755	normal	--	--	--	--	--	[S]	Function unknown	Olfactory receptor 4-like	Protein odr-4 homolog GN=ODR4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein odr-4 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000157184(CPT2)	--	5.814759061	333	3.946068305	225	4.699673642	268	6.0065702	336	5.874339212	336	5.477364503	301	0.968267151	-0.017811397	normal	0.360891654	0.554043677	normal	0.955380788	0.158395238	normal	0.46569764	0.214821374	normal	--	--	"Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K08766|0|hsa:1376|CPT2, CPT1, CPTASE, IIAE4; carnitine palmitoyltransferase 2 (EC:2.3.1.21); K08766 carnitine O-palmitoyltransferase 2 [EC:2.3.1.21] (A)"	Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	Choline/Carnitine o-acyltransferase	"Carnitine O-palmitoyltransferase 2, mitochondrial (Precursor) GN=CPT2 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: carnitine O-palmitoyltransferase 2, mitochondrial [Myotis lucifugus]"
ENSG00000157191(NECAP2)	--	13.05600325	548	12.21009777	517	13.87104102	584	18.36176498	770	17.99838465	752	15.82319779	666	0.522411839	0.458760655	normal	0.317014029	0.517879047	normal	0.956120376	0.180823604	normal	0.035647861	0.38660373	normal	--	--	Biological Process: endocytosis (GO:0006897);; Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1681)	Adaptin ear-binding coat-associated protein 2 GN=NECAP2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: adaptin ear-binding coat-associated protein 2 isoform X2 [Galeopterus variegatus]
ENSG00000157193(LRP8)	--	17.60040318	1710	18.41278351	1792	19.45837054	1746	12.1471473	1262	14.17781537	1417	15.44571402	1496	0.471860613	-0.468624404	normal	0.845466477	-0.359815084	normal	0.958369263	-0.231018427	normal	0.026370725	-0.350663784	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; SMP-30/Gluconolaconase/LRE-like region;; Complement Clr-like EGF-like;; Calcium-binding EGF domain	Low-density lipoprotein receptor-related protein 8 (Precursor) GN=LRP8 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 8 isoform X1 [Orycteropus afer afer]
ENSG00000157211(CDCP2)	--	0	0	0.034711895	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CUB domain;; Zona pellucida-like domain;; CUB-like domain	CUB domain-containing protein 2 (Precursor) GN=CDCP2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: CUB domain-containing protein 2 [Galeopterus variegatus]
ENSG00000157212(PAXIP1)	--	8.972819689	681	8.560586834	670	9.624025369	724	8.551452488	647	9.72869679	755	7.205005547	552	0.969789529	-0.104479468	normal	0.96383679	0.150568701	normal	0.72411756	-0.398656178	normal	0.678111511	-0.108063485	normal	--	--	--	"K14972|0|hsa:22976|PAXIP1, CAGF29, PACIP1, PAXIP1L, PTIP, TNRC2; PAX interacting (with transcription-activation domain) protein 1; K14972 PAX-interacting protein 1 (A)"	--	[KTDL]	"Transcription;; Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	twin BRCT domain;; BRCA1 C Terminus (BRCT) domain	PAX-interacting protein 1 GN=PAXIP1 OS=Homo sapiens (Human) PE=1 SV=2	DKLT	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair;; Signal transduction mechanisms"	PREDICTED: PAX-interacting protein 1 isoform 2 [Dasypus novemcinctus] 
ENSG00000157214(STEAP2)	--	15.30940366	1284	11.43220167	988	13.70521799	1230	11.97358341	1037	13.43863448	1172	15.51619055	1272	0.859396798	-0.338609689	normal	0.951667987	0.224647041	normal	0.981597053	0.040100429	normal	0.930150169	-0.029038295	normal	[R]	General function prediction only	--	"K14738|0|hsa:261729|STEAP2, IPCA1, PCANAP1, PUMPCn, STAMP1, STMP; STEAP family member 2, metalloreductase; K14738 metalloreductase STEAP2 [EC:1.16.1.-] (A)"	Mineral absorption (ko04978)	--	--	Ferric reductase like transmembrane component;; NADP oxidoreductase coenzyme F420-dependent	Metalloreductase STEAP2 GN=STEAP2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: metalloreductase STEAP2 [Ailuropoda melanoleuca] 
ENSG00000157216(SSBP3)	--	6.484617686	302	5.579075917	230	4.17951652	229	5.789199654	341	8.897308953	387	4.83488503	232	0.957997445	0.143702645	normal	0.027929059	0.725556579	normal	0.967004917	0.010417416	normal	0.458884652	0.312867186	normal	--	--	--	--	--	[LKR]	"Replication, recombination and repair;; Transcription;; General function prediction only"	"Single-stranded DNA binding protein, SSDP"	Single-stranded DNA-binding protein 3 GN=SSBP3 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: single-stranded DNA-binding protein 3 [Camelus bactrianus] 
ENSG00000157227(MMP14)	--	1.2883342	73	0.6506194	54	0.500766141	49	0.701205	66	2.169464	100	1.150484	83	0.970201269	-0.17244349	normal	0.270364337	0.849800201	normal	0.636579972	0.734433589	normal	0.328937134	0.479789977	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	K07763|0|pps:100990208|MMP14; matrix metallopeptidase 14 (membrane-inserted); K07763 matrix metalloproteinase-14 (membrane-inserted) [EC:3.4.24.80] (A)	TNF signaling pathway (ko04668);; GnRH signaling pathway (ko04912)	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Domain of unknown function (DUF3377);; Putative peptidoglycan binding domain	Matrix metalloproteinase-14 (Precursor) GN=MMP14 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: matrix metalloproteinase-14 [Equus przewalskii]
ENSG00000157240(FZD1)	--	4.26496	437	3.34258	346	2.95494	304	1.68112	174	2.0191	207	1.81775	187	2.04E-09	-1.351569302	down	0.019621307	-0.758233819	normal	0.061008863	-0.704809502	normal	0.000150769	-0.957673654	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	K02432|0|hsa:8321|FZD1; frizzled class receptor 1; K02432 frizzled 1/7 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain;; Slime mold cyclic AMP receptor	Frizzled-1 (Precursor) GN=FZD1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: frizzled-1 [Ceratotherium simum simum]
ENSG00000157259(GATAD1)	--	17.96246	1093	17.605112	1078	15.82914	969	20.690144	1266	21.89446	1346	21.05626	1285	0.966157216	0.180915293	normal	0.91132639	0.298519236	normal	0.729106737	0.398366743	normal	0.089121178	0.290290332	normal	--	--	--	--	--	--	--	GATA zinc finger	GATA zinc finger domain-containing protein 1 GN=GATAD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GATA zinc finger domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000157303(SUSD3)	--	0.51553791	8	0.380394831	2	1.569712226	14	0.181026615	3	0.055638255	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sushi domain (SCR repeat)	Sushi domain-containing protein 3 GN=SUSD3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: sushi domain-containing protein 3 [Tupaia chinensis] 
ENSG00000157315(TMED6)	--	0	0	0	0	0.0743661	0	0.373098	5	0.296029	3	0.14975	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 6 (Precursor) GN=TMED6 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 6 [Tursiops truncatus]
ENSG00000157322(CLEC18A)	--	0.026007881	1	0	0	0.206517019	0	0.13473874	6	0.211658023	0	0.212778022	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family;; Lectin C-type domain;; Human growth factor-like EGF	C-type lectin domain family 18 member B (Precursor) GN=CLEC18B OS=Homo sapiens (Human) PE=2 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 18 member A-like [Pteropus alecto]
ENSG00000157326(DHRS4)	--	24.53258926	471	27.56946	513	26.167347	518	21.193983	372	13.322693	247	17.7942193	319	0.80307156	-0.369895295	normal	3.79E-06	-1.071218214	down	0.019144988	-0.705038017	normal	0.00024484	-0.701009113	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K11147|1.42973e-173|pon:100172190|DHRS4, PSCD; dehydrogenase/reductase (SDR family) member 4 (EC:1.1.1.184); K11147 dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-] (A)"	Retinol metabolism (ko00830);; Peroxisome (ko04146)	[R]	General function prediction only	Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase;; KR domain	Dehydrogenase/reductase SDR family member 4 GN=DHRS4 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 4-like isoform X1 [Myotis lucifugus]
ENSG00000157330(C1orf158)	--	0.0135361	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf158 GN=C1orf158 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C1orf158 homolog [Oryctolagus cuniculus]
ENSG00000157335(CLEC18C)	--	0	0	0	0	0	0	0.056167611	2	0.373420393	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family;; Lectin C-type domain;; Human growth factor-like EGF	C-type lectin domain family 18 member B (Precursor) GN=CLEC18B OS=Homo sapiens (Human) PE=2 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 18 member A-like [Pteropus alecto]
ENSG00000157343(ARMC12)	--	0.66550713	25	0.859246009	29	0.60791328	21	0.284004043	8	0.231960213	8	0.458808	16	0.639118592	-1.503906128	normal	0.259436842	-1.700719134	normal	0.985773403	-0.370000054	normal	0.061556242	-1.2483628	normal	--	--	--	--	--	--	--	Armadillo-like;; HEAT-like repeat	Armadillo repeat-containing protein 12 GN=ARMC12 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing protein 12 [Galeopterus variegatus]
ENSG00000157349(DDX19B)	--	27.1877209	1470	29.1561103	1668	28.64030398	1592	28.87994083	1509	27.88210051	1581	28.71463382	1595	0.983956099	0.006937231	normal	0.98141679	-0.098616626	normal	0.984688879	-0.005570068	normal	0.900147375	-0.034798459	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K18655|0|ptr:454213|DDX19B, DDX19, DDX19A; DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B (EC:3.6.4.13); K18655 ATP-dependent RNA helicase DDX19/DBP5 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	ATP-dependent RNA helicase DDX19B GN=DDX19B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX19B isoform X7 [Canis lupus familiaris]
ENSG00000157350(ST3GAL2)	--	15.1768203	1408	12.267102	1158	13.517847	1283	12.488495	1173	12.116128	1147	10.363704	989	0.915518506	-0.293924588	normal	0.980312735	-0.035150296	normal	0.770318161	-0.383254145	normal	0.182675431	-0.239712066	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03368|0|hsa:6483|ST3GAL2, Gal-NAc6S, SIAT4B, ST3GALII, ST3GalA.2; ST3 beta-galactoside alpha-2,3-sialyltransferase 2 (EC:2.4.99.4); K03368 beta-galactoside alpha-2,3-sialyltransferase (sialyltransferase 4B) [EC:2.4.99.4] (A)"	Mucin type O-Glycan biosynthesis (ko00512);; Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - globo series (ko00603);; Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 GN=ST3GAL2 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 2 [Oryctolagus cuniculus]"
ENSG00000157353(FUK)	--	3.791134357	297	3.5151724	286	3.600805873	282	3.926093941	302	4.5765585	351	4.212064974	322	0.967776281	-0.006712211	normal	0.914942598	0.272725682	normal	0.950512413	0.182159296	normal	0.639296125	0.151714296	normal	--	--	"Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	"K05305|0|hsa:197258|FUK, 1110046B12Rik; fucokinase (EC:2.7.1.52); K05305 fucokinase [EC:2.7.1.52] (A)"	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	L-fucokinase;; GHMP kinases C terminal	L-fucose kinase GN=FUK OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: L-fucose kinase [Equus caballus]
ENSG00000157368(IL34)	--	0.126996018	3	0.119628934	3	0.285419065	2	0.036415676	1	0	0	0.072590232	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: positive regulation of protein phosphorylation (GO:0001934);; Molecular Function: macrophage colony-stimulating factor receptor binding (GO:0005157);; Cellular Component: extracellular space (GO:0005615);; Biological Process: positive regulation of cell proliferation (GO:0008284);; 	--	--	--	--	Interleukin 34	Interleukin-34 (Precursor) GN=IL34 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: interleukin-34 [Galeopterus variegatus]
ENSG00000157379(DHRS1)	--	8.2216	194	6.47368	156	8.423802	202	10.7813	256	10.7526	253	7.3862	175	0.853248951	0.366719858	normal	0.15677426	0.671010881	normal	0.946456952	-0.213572402	normal	0.377810787	0.287445467	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K11163|0|hsa:115817|DHRS1, SDR19C1; dehydrogenase/reductase (SDR family) member 1; K11163 dehydrogenase/reductase SDR family member 1 [EC:1.1.-.-] (A)"	--	[R]	General function prediction only	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Dehydrogenase/reductase SDR family member 1 GN=DHRS1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 1 [Galeopterus variegatus]
ENSG00000157388(CACNA1D)	--	0.100220065	18	0.094726571	13	0.248563638	15	0.16122327	21	0.25247019	35	0.25455888	32	0.988582944	0.177522884	normal	0.505287576	1.311240867	normal	0.850635719	1.013425486	normal	0.170322516	0.915984644	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04851|0|hsa:776|CACNA1D, CACH3, CACN4, CACNL1A2, CCHL1A2, Cav1.3, PASNA, SANDD; calcium channel, voltage-dependent, L type, alpha 1D subunit; K04851 voltage-dependent calcium channel L type alpha-1D (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Carbohydrate digestion and absorption (ko04973);; Alzheimer's disease (ko05010);; Amphetamine addiction (ko05031);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Voltage gated calcium channel IQ domain;; Polycystin cation channel	Voltage-dependent L-type calcium channel subunit alpha-1D GN=CACNA1D OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent L-type calcium channel subunit alpha-1D isoform 1 [Ceratotherium simum simum]
ENSG00000157399(ARSE)	--	20.70844228	674	22.40144308	657	20.203669	641	23.4608492	821	29.092991	967	45.18528	1441	0.930330748	0.25327758	normal	0.236188021	0.535174763	normal	2.10E-09	1.158510319	up	0.113697918	0.691865306	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K18222|0|hsa:415|ARSE, ASE, CDPX, CDPX1, CDPXR; arylsulfatase E (chondrodysplasia punctata 1) (EC:3.1.6.1); K18222 arylsulfatase E [EC:3.1.6.-] (A)"	--	[R]	General function prediction only	Sulfatase;; C-terminal region of aryl-sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	Arylsulfatase E (Precursor) GN=ARSE OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: arylsulfatase E [Ceratotherium simum simum]
ENSG00000157423(HYDIN)	--	0.620431762	33	1.031616549	45	1.050733772	24	0.996056737	51	1.277285845	59	0.716803624	36	0.929413914	0.575502982	normal	0.957870909	0.358805727	normal	0.960923251	0.548292407	normal	0.426308471	0.494567824	normal	--	--	--	"K17570|0|pps:100970183|HYDIN; HYDIN, axonemal central pair apparatus protein; K17570 hydrocephalus-inducing protein (A)"	--	--	--	Flagellar-associated PapD-like;; MSP (Major sperm protein) domain	Hydrocephalus-inducing protein homolog GN=HYDIN OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: hydrocephalus-inducing protein homolog isoform X1 [Canis lupus familiaris] 
ENSG00000157426(AASDH)	--	3.31849942	186	3.073480001	171	2.677891728	150	3.87687358	223	3.547104955	202	4.151403	234	0.941033624	0.229178121	normal	0.944280746	0.217163741	normal	0.272316808	0.628144087	normal	0.257269258	0.356917972	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K00142|0|ptr:471237|AASDH; aminoadipate-semialdehyde dehydrogenase; K00142 acyl-CoA synthetase [EC:6.2.1.-] (A)	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	AMP-binding enzyme;; PQQ-like domain;; PQQ-like domain;; PQQ enzyme repeat;; Phosphopantetheine attachment site	Acyl-CoA synthetase family member 4 GN=AASDH OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: acyl-CoA synthetase family member 4 [Orcinus orca]
ENSG00000157429(ZNF19)	--	1.56765561	86	1.467390177	70	2.184766691	89	1.285999546	68	1.844455943	62	1.118881875	56	0.939996114	-0.362335409	normal	0.968128638	-0.192100335	normal	0.71213273	-0.662356594	normal	0.407844355	-0.418973012	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7567|ZNF19, KOX12; zinc finger protein 19; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 19 GN=ZNF19 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: zinc finger protein 19 isoform X1 [Felis catus]
ENSG00000157445(CACNA2D3)	--	0.121018902	4	0.399354164	10	0.595816717	4	0.285823398	9	0.99812903	17	0.441544966	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04860|0|hsa:55799|CACNA2D3, HSA272268; calcium channel, voltage-dependent, alpha 2/delta subunit 3; K04860 voltage-dependent calcium channel alpha-2/delta-3 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	VWA N-terminal;; Cache domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Voltage-dependent calcium channel subunit delta-3 (Precursor) GN=CACNA2D3 OS=Homo sapiens (Human) PE=1 SV=1	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: voltage-dependent calcium channel subunit alpha-2/delta-3 [Physeter catodon]
ENSG00000157450(RNF111)	--	16.46206293	1389	18.6401108	1488	16.3968517	1400	15.1086836	1309	17.42722544	1509	15.05812488	1374	0.977993184	-0.116281237	normal	0.983647638	-0.00120706	normal	0.982859093	-0.035297776	normal	0.849439103	-0.050006181	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K10635|0|mcf:102127303|RNF111; ring finger protein 111; K10635 E3 ubiquitin-protein ligase Arkadia [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"E3 ubiquitin-protein ligase Arkadia N-terminus;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase Arkadia GN=RNF111 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase Arkadia isoform 1 [Ceratotherium simum simum]
ENSG00000157456(CCNB2)	--	48.520308	1333	41.91282137	1157	42.95736693	1180	49.01723931	1375	49.44241256	1371	45.12813777	1262	0.982893155	0.013906793	normal	0.95563269	0.22314495	normal	0.97903983	0.088523887	normal	0.638226796	0.105614085	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	"K05868|0|hsa:9133|CCNB2, HsT17299; cyclin B2; K05868 cyclin B (A)"	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Oocyte meiosis (ko04114);; p53 signaling pathway (ko04115);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G2/mitotic-specific cyclin-B2 GN=CCNB2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: G2/mitotic-specific cyclin-B2 [Ceratotherium simum simum]
ENSG00000157470(FAM81A)	--	6.695838422	369	7.10610262	364	8.306200819	483	6.9491236	312	6.274148455	274	8.080591898	386	0.91518289	-0.271675073	normal	0.709614172	-0.42912667	normal	0.860849204	-0.330553519	normal	0.241491081	-0.34319999	normal	--	--	--	--	--	--	--	--	Protein FAM81A GN=FAM81A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM81A isoform X2 [Canis lupus familiaris]
ENSG00000157483(MYO1E)	--	87.82108879	10259	69.1251114	8648	86.04834037	9651	80.357896	9012	75.27885987	8734	98.43883556	11218	0.989545173	-0.217768326	normal	0.995628559	-0.007149306	normal	0.990881264	0.208743339	normal	1	-0.000119176	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10356|0|hsa:4643|MYO1E, FSGS6, HuncM-IC, MYO1C; myosin IE; K10356 myosin I (A)"	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Unconventional myosin-Ie GN=MYO1E OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-Ie isoform X2 [Canis lupus familiaris]
ENSG00000157500(APPL1)	--	9.911077782	935	10.67532077	1018	10.52609647	976	11.09514021	1062	9.478522136	899	8.686973555	825	0.968913103	0.152677721	normal	0.957276221	-0.200453971	normal	0.936017429	-0.250356012	normal	0.70378006	-0.094220121	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08733|0|ptr:460469|APPL1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; K08733 DCC-interacting protein 13 alpha (A)"	Pathways in cancer (ko05200);; Colorectal cancer (ko05210)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; PH domain	DCC-interacting protein 13-alpha OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: DCC-interacting protein 13-alpha isoformX2 [Canis lupus familiaris]
ENSG00000157510(AFAP1L1)	--	2.127281951	200	2.540199893	242	2.620799	219	2.447701932	231	1.891259054	176	1.8625684	161	0.953042519	0.175803179	normal	0.677420732	-0.477344433	normal	0.758684255	-0.448534674	normal	0.490810223	-0.241182906	normal	--	--	--	--	--	--	--	PH domain	Actin filament-associated protein 1-like 1 GN=AFAP1L1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: actin filament-associated protein 1-like 1 [Tupaia chinensis]
ENSG00000157514(TSC22D3)	--	12.12711451	356	11.06186307	292	11.17190968	300	6.228564484	183	7.320644163	231	9.125797322	225	0.00014665	-0.984822076	normal	0.851486456	-0.357415619	normal	0.753513837	-0.420870452	normal	0.012045626	-0.589683672	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	TSC-22/dip/bun family	TSC22 domain family protein 3 GN=TSC22D3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: TSC22 domain family protein 3 isoform X1 [Tupaia chinensis] 
ENSG00000157538(DSCR3)	--	12.2181347	595	12.21010387	681	10.61920647	538	9.037745	473	8.029486005	410	12.347607	640	0.810780837	-0.360834012	normal	0.005027798	-0.751282957	normal	0.933280115	0.241551032	normal	0.4171927	-0.272907611	normal	--	--	--	--	--	[R]	General function prediction only	"Vacuolar protein sorting-associated protein 26;; Arrestin (or S-antigen), N-terminal domain"	Down syndrome critical region protein 3 GN=DSCR3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: Down syndrome critical region protein 3 [Tupaia chinensis]
ENSG00000157540(DYRK1A)	--	10.30223023	693	7.646277762	772	5.817641959	617	5.85282154	646	6.328983927	660	8.521837901	890	0.9664906	-0.131850584	normal	0.933336034	-0.247037376	normal	0.277184464	0.519178152	normal	0.895946735	0.05634649	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08825|0|pps:100976158|DYRK1A; dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A; K08825 dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:2.7.12.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Dual specificity tyrosine-phosphorylation-regulated kinase 1A GN=DYRK1A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity tyrosine-phosphorylation-regulated kinase 1A isoform X1 [Bubalus bubalis]
ENSG00000157542(KCNJ6)	--	0.0487533	17	0.060762	21	0.031701	10	0.0229652	8	0.0639003	22	0.0341076	12	--	--	--	0.987382267	0.042684417	normal	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05000|0|tup:102502044|KCNJ6; potassium inwardly-rectifying channel, subfamily J, member 6; K05000 potassium inwardly-rectifying channel subfamily J member 6 (A)"	Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Estrogen signaling pathway (ko04915);; Oxytocin signaling pathway (ko04921);; Morphine addiction (ko05032)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	G protein-activated inward rectifier potassium channel 2 GN=KCNJ6 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: G protein-activated inward rectifier potassium channel 2 isoform X1 [Bos taurus]
ENSG00000157551(KCNJ15)	--	0.028384022	4	0	0	0	0	0.021233062	3	0.249902756	4	0.021368037	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05008|0|ptr:747512|KCNJ15; potassium inwardly-rectifying channel, subfamily J, member 15; K05008 potassium inwardly-rectifying channel subfamily J member 15 (A)"	Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	ATP-sensitive inward rectifier potassium channel 15 GN=KCNJ15 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: ATP-sensitive inward rectifier potassium channel 15 isoformX3 [Canis lupus familiaris] 
ENSG00000157557(ETS2)	--	8.592917171	570	7.552327829	492	9.048981534	590	32.27327693	2102	32.73372574	2106	29.04289212	1887	0	1.849119786	up	0	2.072997085	up	0	1.666492603	up	4.33E-43	1.86215339	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K02678|0|ptr:473996|ETS2; v-ets avian erythroblastosis virus E26 oncogene homolog 2; K02678 c-ets proto-oncogene protein (A)	Ras signaling pathway (ko04014);; Dorso-ventral axis formation (ko04320);; HTLV-I infection (ko05166)	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	Protein C-ets-2 GN=ETS2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein C-ets-2 isoform X1 [Tupaia chinensis] 
ENSG00000157570(TSPAN18)	--	2.94181172	235	2.191591558	151	3.794993482	196	3.75792639	241	5.40277342	403	2.85437432	185	0.967044317	0.005504589	normal	3.06E-09	1.385977756	up	0.963984266	-0.090897814	normal	0.492909278	0.489009903	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17353|8.81776e-122|pps:100976724|TSPAN18; tetraspanin 18; K17353 tetraspanin-18 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-18 GN=TSPAN18 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: tetraspanin-18 [Camelus ferus]
ENSG00000157578(LCA5L)	--	0.547575143	22	1.149541921	37	0.510079	19	0.74130434	30	0.532845136	19	0.555683521	20	0.979357232	0.393048355	normal	0.83331322	-0.929046543	normal	0.988910859	0.060978196	normal	0.848276962	-0.200364962	normal	--	--	--	--	--	--	--	Ciliary protein causing Leber congenital amaurosis disease	Lebercilin-like protein GN=LCA5L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: lebercilin-like protein [Galeopterus variegatus]
ENSG00000157593(SLC35B2)	--	47.28111486	1473	45.87282977	1468	44.08443176	1409	42.06583997	1312	40.36481593	1241	49.04967743	1530	0.965246801	-0.197603415	normal	0.939516882	-0.263479797	normal	0.979665686	0.110454804	normal	0.607456448	-0.112222043	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Biological Process: transmembrane transport (GO:0055085);; 	"K15276|0|pps:100975440|SLC35B2; solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2; K15276 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 (A)"	--	[G]	Carbohydrate transport and metabolism	UAA transporter family;; EamA-like transporter family	Adenosine 3'-phospho 5'-phosphosulfate transporter 1 GN=SLC35B2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: adenosine 3'-phospho 5'-phosphosulfate transporter 1 isoform X1 [Galeopterus variegatus]
ENSG00000157600(TMEM164)	--	17.799821	1673	17.49824126	1690	17.52445918	1682	18.876432	1770	17.919807	1677	19.8794	1892	0.984706456	0.05043462	normal	0.984553021	-0.032537887	normal	0.976576112	0.161306125	normal	0.811018345	0.060695507	normal	--	--	--	--	--	--	--	TMEM164 family	Transmembrane protein 164 GN=TMEM164 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 164 [Oryctolagus cuniculus]
ENSG00000157601(MX1)	--	0.199772338	15	0.19889533	13	1.51590544	15	0.9699561	48	1.155355949	76	0.741844509	48	0.045931005	1.553918036	normal	2.37E-07	2.397049131	up	0.036294252	1.57646146	normal	5.98E-05	1.979212624	up	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K14754|0|hsa:4599|MX1, IFI-78K, IFI78, MX, MxA; MX dynamin-like GTPase 1; K14754 interferon-induced GTP-binding protein Mx1 (A)"	Measles (ko05162);; Influenza A (ko05164)	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Dynamin central region;; Dynamin family;; Dynamin GTPase effector domain	"Interferon-induced GTP-binding protein Mx1, N-terminally processed GN=MX1 OS=Homo sapiens (Human) PE=1 SV=4"	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: interferon-induced GTP-binding protein Mx1 [Tupaia chinensis]
ENSG00000157613(CREB3L1)	--	1.6926865	91	1.0494119	49	1.291446	63	1.20822187	71	1.953576909	97	0.562991615	34	0.930980686	-0.381565268	normal	0.145114192	0.942727938	normal	0.596704971	-0.869273381	normal	0.986743899	-0.029714594	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09048|0|hsa:90993|CREB3L1, OASIS; cAMP responsive element binding protein 3-like 1; K09048 cyclic AMP-responsive element-binding protein 3 (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Processed cyclic AMP-responsive element-binding protein 3-like protein 1 GN=CREB3L1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cyclic AMP-responsive element-binding protein 3-like protein 1 [Mustela putorius furo] 
ENSG00000157617(C2CD2)	--	4.042373366	459	4.001603268	446	3.857056119	440	4.1059144	470	3.744955837	428	3.615605826	415	0.971009768	0.003323346	normal	0.966710594	-0.080580525	normal	0.966379076	-0.092356722	normal	0.874611439	-0.056368157	normal	--	--	--	--	--	--	--	C2 domain	C2 domain-containing protein 2 (Precursor) GN=C2CD2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: C2 domain-containing protein 2 [Ceratotherium simum simum]
ENSG00000157625(TAB3)	--	7.696126372	886	8.358946021	858	8.79111994	886	7.617614769	864	7.43294843	839	7.912849056	903	0.976190651	-0.066990004	normal	0.9759861	-0.053637787	normal	0.978188054	0.019095561	normal	0.908716207	-0.034263319	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12793|0|ptr:473550|TAB3; TGF-beta activated kinase 1/MAP3K7 binding protein 3; K12793 TAK1-binding protein 3 (A)	NF-kappa B signaling pathway (ko04064);; NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668)	--	--	CUE domain	TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 GN=TAB3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 isoformX1 [Canis lupus familiaris] 
ENSG00000157637(SLC38A10)	--	61.232984	4669	50.662811	4061	53.09305421	4216	42.050018	3290	47.95921859	3676	53.376956	4098	0.253114348	-0.535647083	normal	0.985759926	-0.165060179	normal	0.991992659	-0.049228413	normal	0.157255696	-0.247183287	normal	--	--	--	"K14996|0|hsa:124565|SLC38A10; solute carrier family 38, member 10; K14996 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 10 (A)"	--	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Putative sodium-coupled neutral amino acid transporter 10 GN=SLC38A10 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: putative sodium-coupled neutral amino acid transporter 10 isoform X2 [Galeopterus variegatus]
ENSG00000157653(C9orf43)	--	0.390508552	16	0.073726046	3	0.3140831	12	0.31680004	13	0.4007435	16	0.750770726	31	--	--	--	--	--	--	0.685466858	1.259078507	normal	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4647)	Uncharacterized protein C9orf43 GN=C9orf43 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf43 homolog [Galeopterus variegatus]
ENSG00000157654(PALM2-AKAP2)	--	16.77996361	2351	15.61638074	2217	18.06715966	2481	25.90061945	3661	20.24850463	2843	21.0969935	2994	0.053838526	0.607810306	normal	0.903578468	0.33717521	normal	0.958845666	0.262715069	normal	0.012008937	0.408462535	normal	--	--	Biological Process: regulation of cell shape (GO:0008360);; Cellular Component: membrane (GO:0016020);; 	"K16519|0|hsa:445815|PALM2-AKAP2, AKAP2; PALM2-AKAP2 readthrough; K16519 A-kinase anchor protein 2 (A)"	--	--	--	A-kinase anchor protein 2 C-terminus;; Paralemmin;; RII binding domain	A-kinase anchor protein 2 GN=AKAP2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: A-kinase anchor protein 2 isoform X2 [Tupaia chinensis]
ENSG00000157657(ZNF618)	--	6.047537352	1108	8.180966396	1378	6.600596099	1186	7.021238889	1282	9.143765212	1575	7.798737973	1310	0.966723382	0.179374735	normal	0.971729102	0.17117357	normal	0.974923785	0.1350075	normal	0.47637683	0.161290395	normal	--	--	--	--	--	[L]	"Replication, recombination and repair"	"C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc finger, C2H2 type"	Zinc finger protein 618 GN=ZNF618 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: zinc finger protein 618 isoform 1 [Odobenus rosmarus divergens]
ENSG00000157680(DGKI)	--	0	0	0	0	0	0	0.035431278	2	0.02316862	1	0.064821235	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: diacylglycerol kinase activity (GO:0004143);; Biological Process: protein kinase C-activating G-protein coupled receptor signaling pathway (GO:0007205);; Molecular Function: kinase activity (GO:0016301);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K00901|0|oas:101108481|DGKI; diacylglycerol kinase, iota; K00901 diacylglycerol kinase (ATP) [EC:2.7.1.107] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Diacylglycerol kinase accessory domain;; Diacylglycerol kinase catalytic domain;; Ankyrin repeats (3 copies);; Phorbol esters/diacylglycerol binding domain (C1 domain);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Diacylglycerol kinase iota GN=DGKI OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: diacylglycerol kinase iota [Ovis aries]
ENSG00000157693(TMEM268)	--	6.285307682	471	6.764959928	561	5.553680655	423	5.150818	401	6.332195	488	7.177423	575	0.919627448	-0.262029475	normal	0.940232532	-0.221904195	normal	0.637853782	0.433279245	normal	0.985016047	-0.011581169	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4481)	Transmembrane protein C9orf91 GN=C9orf91 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein C9orf91 homolog isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000157703(SVOPL)	--	0.050366307	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Major Facilitator Superfamily;; Sugar (and other) transporter	Putative transporter SVOPL GN=SVOPL OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: putative transporter SVOPL [Oryctolagus cuniculus]
ENSG00000157734(SNX22)	--	1.34793	97	1.03836	77	0.963308	71	0.664117	48	0.851683	61	0.619833	45	0.063842639	-1.022280383	normal	0.946274775	-0.349739694	normal	0.819200509	-0.648683772	normal	0.128414852	-0.691373139	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17941|3.38679e-139|pps:100974618|SNX22; sorting nexin 22; K17941 sorting nexin-22/24 (A)	--	[ZUD]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	PX domain	Sorting nexin-22 GN=SNX22 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-22 isoform X1 [Galeopterus variegatus]
ENSG00000157741(UBN2)	--	3.520218748	600	4.862079239	834	3.47198092	629	3.111301316	596	3.161901527	573	4.396301527	810	0.972913918	-0.040378688	normal	0.167374814	-0.561702261	normal	0.818997221	0.35581468	normal	0.873271495	-0.080564307	normal	--	--	--	K17492|0|hsa:254048|UBN2; ubinuclein 2; K17492 ubinuclein (A)	--	[KT]	Transcription;; Signal transduction mechanisms	Ubinuclein conserved middle domain;; HPC2 and ubinuclein domain	Ubinuclein-2 GN=UBN2 OS=Homo sapiens (Human) PE=1 SV=2	KT	Transcription;; Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ubinuclein-2 [Equus caballus]
ENSG00000157764(BRAF)	--	5.26593	475	5.71768	500	5.34313	486	5.27452	512	6.8609	636	6.53778	582	0.968863699	0.077143668	normal	0.866840293	0.324799259	normal	0.927260791	0.251056617	normal	0.332467214	0.22306265	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: receptor signaling protein activity (GO:0005057);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K04365|0|pps:100971666|BRAF; B-Raf proto-oncogene, serine/threonine kinase; K04365 B-Raf proto-oncogene serine/threonine-protein kinase [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; FoxO signaling pathway (ko04068);; mTOR signaling pathway (ko04150);; Vascular smooth muscle contraction (ko04270);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Alcoholism (ko05034);; Hepatitis C (ko05160);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Raf-like Ras-binding domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Kinase-like	Serine/threonine-protein kinase B-raf GN=BRAF OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase B-raf isoform X2 [Eptesicus fuscus]
ENSG00000157765(SLC34A2)	--	0.014160769	1	0	0	0	0	0.04250187	3	0.063579649	2	0.028029476	2	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: sodium-dependent phosphate transmembrane transporter activity (GO:0015321);; Cellular Component: membrane (GO:0016020);; Biological Process: sodium-dependent phosphate transport (GO:0044341);; 	"K14683|0|pps:100994104|SLC34A2; solute carrier family 34 (type II sodium/phosphate cotransporter), member 2; K14683 solute carrier family 34 (sodium-dependent phosphate cotransporter) (A)"	--	--	--	Na+/Pi-cotransporter	Sodium-dependent phosphate transport protein 2B GN=SLC34A2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transport protein 2B [Oryctolagus cuniculus]
ENSG00000157766(ACAN)	--	0	0	0	0	0	0	0.012290236	2	0	0	0.012209814	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	"K06792|0|hsa:176|ACAN, AGC1, AGCAN, CSPG1, CSPGCP, MSK16, SEDK; aggrecan; K06792 aggrecan 1 (A)"	--	--	--	Extracellular link domain;; Lectin C-type domain;; Immunoglobulin V-set domain;; Sushi domain (SCR repeat);; EGF-like domain;; Human growth factor-like EGF	Aggrecan core protein 2 (Precursor) GN=ACAN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: aggrecan core protein isoform X1 [Sus scrofa]
ENSG00000157778(PSMG3)	--	31.997609	454	35.221245	500	31.115037	442	34.311191	490	33.39864	461	32.955694	474	0.968283461	0.078999819	normal	0.960995808	-0.138152578	normal	0.967012181	0.092244425	normal	0.986272296	0.008198132	normal	--	--	--	"K11877|8.22014e-82|pps:100972721|PSMG3; proteasome (prosome, macropain) assembly chaperone 3; K11877 proteasome assembly chaperone 3 (A)"	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2372)	Proteasome assembly chaperone 3 GN=PSMG3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome assembly chaperone 3 [Tupaia chinensis]
ENSG00000157782(CABP1)	--	0.177898505	6	0	0	0	0	0.073509806	2	0.243039635	6	0.148660127	4	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain;; EF-hand domain pair;; EF-hand domain pair;; EF hand	Calcium-binding protein 1 GN=CABP1 OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: calcium-binding protein 1 isoform X1 [Eptesicus fuscus]
ENSG00000157796(WDR19)	--	3.817890871	331	4.027454726	341	3.726857635	299	6.474862524	349	4.51757344	323	4.228966	347	0.967599801	0.04535851	normal	0.962919122	-0.09921197	normal	0.944273468	0.20553295	normal	0.903211684	0.048160609	normal	--	--	--	--	--	[R]	General function prediction only	"Region in Clathrin and VPS;; TPR repeat;; Coatomer WD associated region;; WD domain, G-beta repeat;; Anaphase-promoting complex, cyclosome, subunit 3"	WD repeat-containing protein 19 GN=WDR19 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 19 isoform 1 [Ceratotherium simum simum]
ENSG00000157800(SLC37A3)	--	18.37856152	864	16.65267622	873	16.42350181	757	18.07876028	849	15.46417555	748	16.60202236	819	0.976489512	-0.055998562	normal	0.937284849	-0.243912941	normal	0.972013325	0.105076852	normal	0.807636512	-0.067434839	normal	[G]	Carbohydrate transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K03447|0|ptr:472534|SLC37A3; solute carrier family 37, member 3; K03447 MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 3 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; Sugar (and other) transporter	Sugar phosphate exchanger 3 GN=SLC37A3 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sugar phosphate exchanger 3 [Vicugna pacos]
ENSG00000157823(AP3S2)	--	61.17913006	3469	59.89408571	3206	58.24970585	3450	73.02654593	4253	68.30476826	4348	69.97505463	4054	0.967154587	0.263023398	normal	0.781813462	0.417981066	normal	0.977020264	0.224367465	normal	0.069138421	0.30055584	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K12399|8.01626e-148|pps:100978041|AP3S2; adaptor-related protein complex 3, sigma 2 subunit; K12399 AP-3 complex subunit sigma (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	AP-3 complex subunit sigma-2 GN=AP3S2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-3 complex subunit sigma-2 [Capra hircus]
ENSG00000157827(FMNL2)	--	38.322967	4335	41.954931	4709	38.539259	4280	17.43487015	1966	12.44025241	1397	19.22463	2169	1.40E-10	-1.170967624	down	0	-1.77340257	down	3.23E-07	-0.988371965	normal	3.04E-22	-1.289298553	down	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain	Formin-like protein 2 GN=FMNL2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: formin-like protein 2 isoform X5 [Mustela putorius furo] 
ENSG00000157833(GAREM2)	--	9.218123497	702	8.08884	622	7.466391	568	5.1444231	377	6.05178474	452	3.9332491	303	4.50E-05	-0.924928918	normal	0.475213305	-0.480641199	normal	0.000135182	-0.911486368	normal	8.43E-05	-0.762914367	normal	--	--	--	--	--	--	--	"Cell-cycle sustaining, positive selection,"	GRB2-associated and regulator of MAPK protein-like GN=GAREML OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: GRB2-associated and regulator of MAPK protein-like isoform X1 [Sus scrofa]
ENSG00000157837(SPPL3)	--	34.62513256	1248	25.78098034	1266	29.6820476	1170	34.866802	1270	36.3000656	1292	38.29828737	1391	0.982151192	-0.005614849	normal	0.981900873	0.007892775	normal	0.948795093	0.241036383	normal	0.737792794	0.080626485	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Cellular Component: integral component of membrane (GO:0016021);; 	K09598|0|ptr:452314|SPPL3; signal peptide peptidase like 3; K09598 signal peptide peptidase-like 3 [EC:3.4.23.-] (A)	--	[S]	Function unknown	Signal peptide peptidase	Signal peptide peptidase-like 3 GN=SPPL3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: signal peptide peptidase-like 3 [Galeopterus variegatus]
ENSG00000157851(DPYSL5)	--	9.040981402	849	6.107995982	639	8.144954596	830	4.562072147	380	5.883776579	508	3.783629506	338	5.14E-09	-1.187294448	down	0.829742064	-0.351478773	normal	1.04E-10	-1.300539227	down	8.25E-05	-0.939982472	normal	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	K07529|0|mcf:102136498|DPYSL5; dihydropyrimidinase-like 5; K07529 dihydropyrimidinase-like 5 (A)	Axon guidance (ko04360)	[F]	Nucleotide transport and metabolism	Amidohydrolase family;; Amidohydrolase;; Amidohydrolase	Dihydropyrimidinase-related protein 5 GN=DPYSL5 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: dihydropyrimidinase-related protein 5 [Pteropus alecto]
ENSG00000157856(DRC1)	--	0.016628	1	0	0	0.0321103	1	0.0164127	1	0.0162378	0	0.032982	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sperm tail;; Sperm tail C-terminal domain	Dynein regulatory complex protein 1 GN=DRC1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 164 [Trichechus manatus latirostris]
ENSG00000157869(RAB28)	--	9.825095545	205	8.399401001	203	12.87461526	247	8.36650902	212	7.979725874	179	11.87177731	259	0.966864513	0.017479272	normal	0.947624683	-0.201348066	normal	0.965759255	0.059792087	normal	0.954960941	-0.031352402	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07915|5.28316e-164|ptr:461120|RAB28; RAB28, member RAS oncogene family; K07915 Ras-related protein Rab-28 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-28 (Precursor) GN=RAB28 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-28 isoform X1 [Eptesicus fuscus]
ENSG00000157870(FAM213B)	--	9.753936311	396	9.452091589	355	8.193243354	349	13.25174847	572	12.07109242	544	8.01039636	335	0.409941458	0.498066613	normal	0.145707172	0.592308474	normal	0.966633864	-0.06706076	normal	0.329164226	0.376848772	normal	--	--	--	"K15717|4.88144e-154|hsa:127281|FAM213B, C1orf93; family with sequence similarity 213, member B (EC:1.11.1.20); K15717 prostamide/prostaglandin F2alpha synthase [EC:1.11.1.20] (A)"	Arachidonic acid metabolism (ko00590)	[S]	Function unknown	AhpC/TSA antioxidant enzyme	Prostamide/prostaglandin F synthase GN=FAM213B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"hypothetical protein M91_10893, partial [Bos mutus]"
ENSG00000157873(TNFRSF14)	--	0.274291671	5	0.60165876	19	0.613154352	15	0.0323641	1	0.24468855	4	0.160375956	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K05152|0|ggo:101133688|TNFRSF14; tumor necrosis factor receptor superfamily member 14; K05152 tumor necrosis factor receptor superfamily member 14 (A)	Cytokine-cytokine receptor interaction (ko04060);; Herpes simplex infection (ko05168)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 14 (Precursor) GN=TNFRSF14 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: tumor necrosis factor receptor superfamily member 14 [Galeopterus variegatus]
ENSG00000157881(PANK4)	--	5.691826703	299	5.278935	280	5.436348	290	5.707273	300	5.023873	262	5.405264394	286	0.967511045	-0.025882472	normal	0.960232835	-0.116635183	normal	0.967356509	-0.02818121	normal	0.89250799	-0.056665557	normal	[H]	Coenzyme transport and metabolism	Molecular Function: pantothenate kinase activity (GO:0004594);; Molecular Function: ATP binding (GO:0005524);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; 	K09680|0|cjc:100396782|PANK4; pantothenate kinase 4; K09680 type II pantothenate kinase [EC:2.7.1.33] (A)	Pantothenate and CoA biosynthesis (ko00770)	[H]	Coenzyme transport and metabolism	Fumble;; Protein of unknown function DUF89	Pantothenate kinase 4 GN=PANK4 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: pantothenate kinase 4 [Sus scrofa]
ENSG00000157890(MEGF11)	--	0.1830185	18	0.293429796	7	0.251773651	18	0.949279251	21	0.691926755	37	0.726992644	21	0.988582944	0.177522884	normal	0.007099711	2.158598281	up	0.987968866	0.198638097	normal	0.223420472	0.857481828	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin EGF-like (Domains III and V);; Human growth factor-like EGF	Multiple epidermal growth factor-like domains protein 11 (Precursor) GN=MEGF11 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: multiple epidermal growth factor-like domains protein 11 isoform X4 [Bos taurus]
ENSG00000157895(C12orf43)	--	7.657916033	438	8.33498909	494	6.12032106	414	8.416254917	647	7.522679863	665	7.230911807	623	0.274550098	0.530462966	normal	0.715103367	0.406341083	normal	0.142675328	0.579572501	normal	0.005856591	0.502146448	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C12orf43 GN=C12orf43 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C12orf43 homolog isoform X2 [Galeopterus variegatus]
ENSG00000157911(PEX10)	--	14.537587	699	14.45892	739	13.04800002	662	16.526008	840	16.4505504	849	14.92460271	778	0.940830695	0.233795326	normal	0.959764015	0.178422773	normal	0.944105661	0.224174631	normal	0.306858496	0.210819931	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metal ion binding (GO:0046872);; 	"K13346|2.07786e-168|hsa:5192|PEX10, NALD, PBD6A, PBD6B, RNF69; peroxisomal biogenesis factor 10; K13346 peroxin-10 (A)"	Peroxisome (ko04146)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Pex2 / Pex12 amino terminal region;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	Peroxisome biogenesis factor 10 GN=PEX10 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxisome biogenesis factor 10 [Tupaia chinensis] 
ENSG00000157916(RER1)	--	58.5192721	1311	59.15313785	1263	48.421462	1342	74.960624	1511	69.040075	1505	64.3295584	1473	0.970692961	0.173813859	normal	0.954765077	0.231228392	normal	0.977632729	0.125945805	normal	0.362559214	0.175838614	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rer1 family	Protein RER1 GN=RER1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein RER1 [Tupaia chinensis]
ENSG00000157927(RADIL)	--	2.308995709	130	1.134259386	82	1.668491022	123	1.237577626	72	1.740698928	101	0.98067385	59	0.093686582	-0.869261069	normal	0.949827579	0.274661938	normal	0.015078029	-1.049125566	normal	0.198617048	-0.551143349	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[Z]	Cytoskeleton	DIL domain;; Ras association (RalGDS/AF-6) domain;; PDZ domain (Also known as DHR or GLGF)	Ras-associating and dilute domain-containing protein GN=RADIL OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: ras-associating and dilute domain-containing protein isoform X3 [Tupaia chinensis] 
ENSG00000157933(SKI)	--	9.0773	901	10.58535	1062	8.69722	886	11.18766	1115	11.20636	1107	11.09803	1111	0.92216345	0.276188431	normal	0.979506673	0.038391351	normal	0.883190114	0.317703529	normal	0.286545473	0.204951905	normal	--	--	Molecular Function: SMAD binding (GO:0046332);; 	--	--	--	--	c-SKI Smad4 binding domain;; SKI/SNO/DAC family	Ski oncogene GN=SKI OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	ski oncogene [Equus caballus] 
ENSG00000157954(WIPI2)	--	25.96420746	1263	26.22410364	1338	27.6461951	1355	30.94248428	1512	28.56101612	1383	26.83920765	1323	0.955583216	0.228516907	normal	0.982383611	0.026267281	normal	0.982283596	-0.042722975	normal	0.773040981	0.070971118	normal	[R]	General function prediction only	--	"K17908|0|ptr:737922|WIPI2; WD repeat domain, phosphoinositide interacting 2; K17908 autophagy-related protein 18 (A)"	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat domain phosphoinositide-interacting protein 2 GN=WIPI2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat domain phosphoinositide-interacting protein 2 isoform X1 [Tupaia chinensis]
ENSG00000157978(LDLRAP1)	--	7.33108	423	7.3169	426	6.90601	403	8.34214	478	7.29381	417	6.43999	371	0.959880528	0.145024963	normal	0.968155631	-0.052045855	normal	0.961601845	-0.127154625	normal	0.994839332	-0.006019229	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12474|0|hsa:26119|LDLRAP1, ARH, ARH1, ARH2, FHCB1, FHCB2; low density lipoprotein receptor adaptor protein 1; K12474 low density lipoprotein receptor adapter protein 1 (A)"	Endocytosis (ko04144)	[R]	General function prediction only	Phosphotyrosine interaction domain (PTB/PID);; Phosphotyrosine interaction domain (PTB/PID);; Phosphotyrosine-binding domain	Low density lipoprotein receptor adapter protein 1 GN=LDLRAP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: low density lipoprotein receptor adapter protein 1 [Odobenus rosmarus divergens]
ENSG00000157985(AGAP1)	--	12.49713252	1738	14.029818	1678	14.24637603	1642	10.075412	1193	9.083782	1234	10.55989103	1146	0.100546034	-0.57305084	normal	0.514434673	-0.464336789	normal	0.229976134	-0.526554804	normal	0.000351885	-0.522771906	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; 	"K12491|0|ocu:100344961|AGAP1; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1; K12491 Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1/3 (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Miro-like protein;; Ras family;; Ankyrin repeats (3 copies);; Ankyrin repeat;; PH domain;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 GN=AGAP1 OS=Homo sapiens (Human) PE=1 SV=4"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X5 [Mustela putorius furo]"
ENSG00000157992(KRTCAP3)	--	0.784231	4	0.165077	2	0.370884	3	0.09903801	1	0.375877	3	0.0958442	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Beta-casein like protein	Keratinocyte-associated protein 3 GN=KRTCAP3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: keratinocyte-associated protein 3 isoform X2 [Mustela putorius furo] 
ENSG00000157999(ANKRD61)	--	0.569955	13	0.882993	20	1.12053	25	1.17773	27	1.14221	26	1.03171	24	0.925049627	0.944757258	normal	0.982359267	0.334830628	normal	0.986746054	-0.063278113	normal	0.655552492	0.387984484	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 61 GN=ANKRD61 OS=Homo sapiens (Human) PE=3 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: ankyrin repeat domain-containing protein 61-like [Odobenus rosmarus divergens]
ENSG00000158006(PAFAH2)	--	5.200067199	308	4.3111303	277	5.583215519	327	5.480274152	318	4.141229712	243	5.367472066	311	0.967920006	0.015189582	normal	0.942823597	-0.209136137	normal	0.965335262	-0.080286714	normal	0.818937265	-0.085861766	normal	--	--	Molecular Function: 1-alkyl-2-acetylglycerophosphocholine esterase activity (GO:0003847);; Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Biological Process: chlorophyll catabolic process (GO:0015996);; Biological Process: lipid catabolic process (GO:0016042);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: chlorophyllase activity (GO:0047746);; 	"K01062|0|hsa:5051|PAFAH2, HSD-PLA2; platelet-activating factor acetylhydrolase 2, 40kDa (EC:3.1.1.47); K01062 platelet-activating factor acetylhydrolase [EC:3.1.1.47] (A)"	Ether lipid metabolism (ko00565)	[I]	Lipid transport and metabolism	"Platelet-activating factor acetylhydrolase, isoform II;; Alpha/beta hydrolase family;; Chlorophyllase enzyme;; Alpha/beta hydrolase family;; Chlorophyllase;; Prolyl oligopeptidase family;; Putative esterase"	"Platelet-activating factor acetylhydrolase 2, cytoplasmic GN=PAFAH2 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: platelet-activating factor acetylhydrolase 2, cytoplasmic [Dasypus novemcinctus]"
ENSG00000158008(EXTL1)	--	0.0139473	1	0.0406808	3	0.0531328	3	0	0	0.027114	1	0.0274914	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K02368|0|hsa:2134|EXTL1, EXTL; exostosin-like glycosyltransferase 1 (EC:2.4.1.224); K02368 alpha-1,4-N-acetylglucosaminyltransferase EXTL1 [EC:2.4.1.224] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[GMW]	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Extracellular structures	Glycosyl transferase family 64 domain;; Exostosin family	Exostosin-like 1 GN=EXTL1 OS=Homo sapiens (Human) PE=2 SV=2	GMW	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: exostosin-like 1 [Galeopterus variegatus]
ENSG00000158019(BRE)	--	53.85631835	1569	38.94758921	1121	44.9573525	1294	44.85304215	1308	54.10807473	1563	48.94516186	1423	0.920025595	-0.293000299	normal	0.539816334	0.457579982	normal	0.976857189	0.128663165	normal	0.784672406	0.087236188	normal	--	--	Cellular Component: BRCA1-A complex (GO:0070531);; Cellular Component: BRISC complex (GO:0070552);; 	K12173|0|mcf:102138281|BRE; brain and reproductive organ-expressed (TNFRSF1A modulator); K12173 BRCA1-A complex subunit BRE (A)	--	--	--	Brain and reproductive organ-expressed protein (BRE)	BRCA1-A complex subunit BRE OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	BRCA1-A complex subunit BRE [Myotis brandtii]
ENSG00000158042(MRPL17)	--	39.315113	1207	37.4620597	1195	38.5424319	1263	40.1548444	1297	39.184419	1180	36.61678125	1138	0.980236211	0.072831098	normal	0.980545593	-0.039599884	normal	0.970937306	-0.158445557	normal	0.884468846	-0.041327959	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02879|1.97611e-109|hsa:63875|MRPL17, L17mt, LIP2, MRP-L17, MRP-L26, RPL17L, RPML26; mitochondrial ribosomal protein L17; K02879 large subunit ribosomal protein L17 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L17	"39S ribosomal protein L17, mitochondrial (Precursor) GN=MRPL17 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L17, mitochondrial [Felis catus]"
ENSG00000158050(DUSP2)	--	0	0	0.0767464	2	0	0	0.157773	4	0.077662	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K04459|0|hsa:1844|DUSP2, PAC-1, PAC1; dual specificity phosphatase 2 (EC:3.1.3.16 3.1.3.48); K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 2 GN=DUSP2 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 2 [Felis catus]
ENSG00000158055(GRHL3)	--	1.732567	104	2.429910095	148	1.99842	122	0.392049372	22	0.24562	13	0.4773295	27	9.64E-09	-2.194373124	down	0	-3.38511921	down	2.16E-09	-2.123019647	down	2.83E-12	-2.61355199	down	--	--	--	K09275|0|mcf:102114920|GRHL3; grainyhead-like 3 (Drosophila); K09275 transcription factor CP2 and related proteins (A)	--	[K]	Transcription	CP2 transcription factor	Grainyhead-like protein 3 homolog GN=GRHL3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: grainyhead-like protein 3 homolog [Galeopterus variegatus]
ENSG00000158062(UBXN11)	--	5.154357742	160	6.82482596	178	6.796286257	184	5.55019608	181	5.996771602	173	5.804557359	192	0.959448251	0.145768933	normal	0.964649745	-0.061997446	normal	0.966088571	0.052685181	normal	0.940260108	0.043946896	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Y]	Nuclear structure	SEP domain	UBX domain-containing protein 11 GN=UBXN11 OS=Homo sapiens (Human) PE=2 SV=2	Y	Nuclear structure	PREDICTED: LOW QUALITY PROTEIN: UBX domain-containing protein 11 [Oryctolagus cuniculus]
ENSG00000158077(NLRP14)	--	0	0	0	0	0	0	0	0	0.0291136	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	NACHT domain;; PAAD/DAPIN/Pyrin domain;; Leucine Rich repeat	"NACHT, LRR and PYD domains-containing protein 14 GN=NLRP14 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: NACHT, LRR and PYD domains-containing protein 14 [Ceratotherium simum simum]"
ENSG00000158079(PTPDC1)	--	2.737632063	327	2.871066382	345	2.783075587	339	2.662576702	304	2.681200808	326	2.346943602	293	0.959216321	-0.135391578	normal	0.962634229	-0.102687812	normal	0.94045933	-0.217630774	normal	0.628904125	-0.152625052	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18078|0|hsa:138639|PTPDC1, PTP9Q22; protein tyrosine phosphatase domain containing 1 (EC:3.1.3.48); K18078 protein tyrosine phosphatase domain-containing protein 1 [EC:3.1.3.-] (A)"	--	--	--	"Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Protein tyrosine phosphatase domain-containing protein 1 GN=PTPDC1 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: protein tyrosine phosphatase domain-containing protein 1-like isoform X1 [Physeter catodon]
ENSG00000158089(GALNT14)	--	20.0273192	1131	19.89180659	1142	20.4523284	1167	15.23625513	846	13.64171939	763	15.52761355	894	0.544890639	-0.448993553	normal	0.071926157	-0.60225147	normal	0.743353959	-0.392166847	normal	0.002116781	-0.479777299	normal	--	--	--	"K00710|0|hsa:79623|GALNT14, GALNT15, GalNac-T10, GalNac-T14; polypeptide N-acetylgalactosaminyltransferase 14 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 14 GN=GALNT14 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 14 isoform 1 [Odobenus rosmarus divergens]
ENSG00000158092(NCK1)	--	17.00999995	410	19.06904078	443	17.08455208	440	19.81810536	510	19.46807375	509	26.06546217	648	0.905573238	0.283088401	normal	0.952840471	0.17836401	normal	0.216946628	0.548635639	normal	0.096893256	0.346083221	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K07365|0|ptr:460720|NCK1; NCK adaptor protein 1; K07365 NCK adaptor protein (A)	ErbB signaling pathway (ko04012);; T cell receptor signaling pathway (ko04660)	[T]	Signal transduction mechanisms	SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; SH2 domain;; Bacterial SH3 domain	Cytoplasmic protein NCK1 GN=NCK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cytoplasmic protein NCK1 isoformX2 [Canis lupus familiaris] 
ENSG00000158104(HPD)	--	0.197000587	7	0	0	0	0	0.064334569	2	0.095418055	2	0.032101177	1	--	--	--	--	--	--	--	--	--	--	--	--	[ER]	Amino acid transport and metabolism;; General function prediction only	--	K00457|0|ptr:473296|HPD; 4-hydroxyphenylpyruvate dioxygenase; K00457 4-hydroxyphenylpyruvate dioxygenase [EC:1.13.11.27] (A)	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360)	[E]	Amino acid transport and metabolism	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily;; Glyoxalase-like domain	4-hydroxyphenylpyruvate dioxygenase GN=HPD OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: 4-hydroxyphenylpyruvate dioxygenase [Tursiops truncatus]
ENSG00000158106(RHPN1)	--	8.07375405	762	7.425447013	745	7.118437026	688	6.11734088	553	6.7100144	592	6.341806088	591	0.389099259	-0.492173247	normal	0.828500208	-0.352265665	normal	0.94109102	-0.227002957	normal	0.052639451	-0.359576049	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[R]	General function prediction only	BRO1-like domain;; Hr1 repeat;; PDZ domain (Also known as DHR or GLGF)	Rhophilin-1 GN=RHPN1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: rhophilin-1 [Galeopterus variegatus]
ENSG00000158109(TPRG1L)	--	11.850829	497	13.07121335	560	12.31998781	518	18.06835262	755	16.80893924	705	16.85173508	706	0.141323636	0.570957129	normal	0.884110687	0.310022284	normal	0.607476219	0.437326818	normal	0.015039378	0.438210903	normal	--	--	--	--	--	--	--	Inositol phosphatase	Tumor protein p63-regulated gene 1-like protein GN=TPRG1L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: tumor protein p63-regulated gene 1-like protein [Ceratotherium simum simum]
ENSG00000158113(LRRC43)	--	0.148649081	2	0.025171867	1	0	0	0	0	0.211315508	3	0.025302136	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat	Leucine-rich repeat-containing protein 43 GN=LRRC43 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 43 [Pteropus alecto]
ENSG00000158122(AAED1)	--	7.649897227	295	8.593439919	333	7.198888058	277	8.057892747	315	7.854699007	303	6.915814939	270	0.966123656	0.063484618	normal	0.954762981	-0.156883682	normal	0.966634871	-0.044969329	normal	0.906273435	-0.049235539	normal	--	--	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[S]	Function unknown	AhpC/TSA antioxidant enzyme;; AhpC/TSA family;; Redoxin	Thioredoxin-like protein AAED1 GN=AAED1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: thioredoxin-like protein AAED1 isoform X1 [Orycteropus afer afer]
ENSG00000158125(XDH)	--	1.04714547	115	0.74457372	83	0.867244988	91	0.756721443	82	0.81920432	95	0.93346273	100	0.818877433	-0.510648875	normal	0.964187059	0.170484527	normal	0.9677339	0.125775553	normal	0.902702768	-0.08182989	normal	[F]	Nucleotide transport and metabolism	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: metal ion binding (GO:0046872);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00106|0|hsa:7498|XDH, XO, XOR; xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2); K00106 xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] (A)"	Purine metabolism (ko00230);; Caffeine metabolism (ko00232);; Drug metabolism - other enzymes (ko00983);; Peroxisome (ko04146)	[F]	Nucleotide transport and metabolism	"Molybdopterin-binding domain of aldehyde dehydrogenase;; FAD binding domain in molybdopterin dehydrogenase;; Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain;; [2Fe-2S] binding domain;; CO dehydrogenase flavoprotein C-terminal domain;; 2Fe-2S iron-sulfur cluster binding domain"	Xanthine oxidase GN=XDH OS=Homo sapiens (Human) PE=1 SV=4	F	Nucleotide transport and metabolism	PREDICTED: xanthine dehydrogenase/oxidase isoform X1 [Tupaia chinensis]
ENSG00000158156(XKR8)	--	4.42164068	168	3.710137672	133	4.366407043	141	4.336211155	163	4.166365941	161	3.72717684	133	0.965628511	-0.073736855	normal	0.940295119	0.251604413	normal	0.965816625	-0.091549187	normal	0.971095564	0.026338315	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	XK-related protein	"XK-related protein 8, processed form GN=XKR8 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	PREDICTED: XK-related protein 8 [Galeopterus variegatus]
ENSG00000158158(CNNM4)	--	8.94906	836	8.229394	775	8.560182554	807	5.006455	467	5.570902513	516	5.190273	486	0.000133904	-0.868744082	normal	0.082689223	-0.606790022	normal	0.00430672	-0.738101944	normal	5.03E-06	-0.739986503	normal	[R]	General function prediction only	--	"K16302|0|hsa:26504|CNNM4, ACDP4; cyclin and CBS domain divalent metal cation transport mediator 4; K16302 metal transporter CNNM (A)"	--	[S]	Function unknown	Domain of unknown function DUF21;; CBS domain	Metal transporter CNNM4 GN=CNNM4 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	Metal transporter CNNM4 [Tupaia chinensis]
ENSG00000158161(EYA3)	--	4.017731693	427	4.102218081	437	4.18680795	447	4.084696	440	4.164189	449	3.594757352	392	0.97031112	0.012391269	normal	0.969699874	0.017595536	normal	0.947551353	-0.197000356	normal	0.878802895	-0.054830199	normal	--	--	--	K17621|0|ptr:469248|EYA3; EYA transcriptional coactivator and phosphatase 3; K17621 eyes absent homolog 3 [EC:3.1.3.48] (A)	--	[R]	General function prediction only	--	Eyes absent homolog 3 GN=EYA3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: eyes absent homolog 3 isoform X1 [Pteropus alecto]
ENSG00000158163(DZIP1L)	--	2.401035584	112	1.367739309	121	1.801183406	86	1.947831187	117	2.272237744	117	2.794485122	101	0.969538842	0.031751375	normal	0.966737259	-0.069047415	normal	0.959520469	0.220080699	normal	0.947441852	0.048486908	normal	--	--	--	K16470|0|ptr:460723|DZIP1L; DAZ interacting zinc finger protein 1-like; K16470 zinc finger protein DZIP1 (A)	--	--	--	Iguana/Dzip1-like DAZ-interacting protein N-terminal	Zinc finger protein DZIP1L GN=DZIP1L OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein DZIP1L [Ceratotherium simum simum]
ENSG00000158164(TMSB15A)	--	0.260135	2	0	0	0.643536	4	0.894089	7	1.00917	7	0.128341	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[N]	Cell motility	--	Thymosin beta-15B GN=TMSB15B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: thymosin beta-15A-like [Sus scrofa] 
ENSG00000158169(FANCC)	--	8.372685	545	7.915881372	535	9.91550989	533	8.985854373	485	8.722524459	484	7.775576176	432	0.948585346	-0.198510058	normal	0.956549249	-0.165466395	normal	0.881853196	-0.310415477	normal	0.337514698	-0.224813079	normal	--	--	Biological Process: DNA repair (GO:0006281);; 	"K10890|0|hsa:2176|FANCC, FA3, FAC, FACC; Fanconi anemia, complementation group C; K10890 fanconi anemia group C protein (A)"	Fanconi anemia pathway (ko03460)	--	--	Fanconi anaemia group C protein	Fanconi anemia group C protein GN=FANCC OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: Fanconi anemia group C protein [Ceratotherium simum simum]
ENSG00000158186(MRAS)	--	4.835773111	411	4.860740998	422	4.564725406	362	4.220852311	343	8.604002	410	8.062435347	397	0.901211114	-0.290571058	normal	0.967464823	-0.062817251	normal	0.961844491	0.124361614	normal	0.82445739	-0.076329671	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07831|1.40997e-135|umr:103678665|MRAS; muscle RAS oncogene homolog; K07831 Ras-related protein M-Ras (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Tight junction (ko04530);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Proteoglycans in cancer (ko05205)	[R]	General function prediction only	Ras family;; Miro-like protein;; Elongation factor Tu GTP binding domain;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase	Ras-related protein M-Ras (Precursor) GN=MRAS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ras-related protein M-Ras isoform X1 [Equus caballus] 
ENSG00000158195(WASF2)	--	25.64692003	2781	26.16782003	2844	26.36202389	2854	22.83062661	2458	19.84642596	2134	25.45781564	2763	0.974258995	-0.20882827	normal	0.67860603	-0.435519487	normal	0.989089428	-0.055011587	normal	0.197888941	-0.22604839	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	"K05748|0|mcc:716082|wiskott-Aldrich syndrome protein family member 2-like; K05748 WAS protein family, member 2 (A)"	Adherens junction (ko04520);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132);; Choline metabolism in cancer (ko05231)	[Z]	Cytoskeleton	WH2 motif	Wiskott-Aldrich syndrome protein family member 2 GN=WASF2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: wiskott-Aldrich syndrome protein family member 2 [Galeopterus variegatus] 
ENSG00000158201(ABHD3)	--	12.03331282	353	14.77773447	432	14.42524687	443	13.82169796	410	9.773348728	291	18.74827567	573	0.950328257	0.184378339	normal	0.18947736	-0.588909452	normal	0.811317801	0.361848024	normal	0.970604033	0.032987957	normal	[R]	General function prediction only	--	"K13696|0|hsa:171586|ABHD3, LABH3; abhydrolase domain containing 3; K13696 abhydrolase domain-containing protein 1/3 (A)"	--	[R]	General function prediction only	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Abhydrolase domain-containing protein 3 GN=ABHD3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: abhydrolase domain-containing protein 3-like [Tupaia chinensis]
ENSG00000158220(ESYT3)	--	0.33134962	30	0.177082866	16	0.221467011	18	0.406159289	30	0.470981814	45	0.537271174	34	0.985137509	-0.029330151	normal	0.164551768	1.389091371	normal	0.902027773	0.856141775	normal	0.241675918	0.747232454	normal	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[R]	General function prediction only	C2 domain	Extended synaptotagmin-3 GN=ESYT3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: extended synaptotagmin-3 [Ceratotherium simum simum]
ENSG00000158234(FAIM)	--	4.442854245	68	7.890510502	120	7.973903891	131	9.132657057	150	9.2763224	152	8.2168193	131	0.002941884	1.093487893	up	0.921191344	0.316064234	normal	0.968607441	-0.008196817	normal	0.268823303	0.419783584	normal	--	--	Biological Process: negative regulation of apoptotic process (GO:0043066);; 	--	--	[T]	Signal transduction mechanisms	Fas apoptotic inhibitory molecule (FAIM1)	Fas apoptotic inhibitory molecule 1 GN=FAIM OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fas apoptotic inhibitory molecule 1 isoform X1 [Camelus ferus] 
ENSG00000158246(FAM46B)	--	0.686505	29	0.341875	15	0.515467	22	0.562426	24	0.275656	11	0.280764	12	0.982780427	-0.287103274	normal	--	--	--	0.964545894	-0.806703784	normal	0.550177513	-0.513421325	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF1693)	Protein FAM46B GN=FAM46B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM46B [Loxodonta africana]
ENSG00000158258(CLSTN2)	--	0.479154944	138	0.474681518	138	0.57806077	167	0.317493752	88	0.331063385	95	0.5908925	169	0.434604029	-0.670492835	normal	0.70053418	-0.552750211	normal	0.967344874	0.008804445	normal	0.485739364	-0.350598421	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	--	--	[W]	Extracellular structures	Cadherin domain;; Concanavalin A-like lectin/glucanases superfamily	Calsyntenin-2 (Precursor) GN=CLSTN2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: calsyntenin-2 [Felis catus]
ENSG00000158270(COLEC12)	--	0.00856493	1	0.0170383	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K10062|0|pon:100431455|COLEC12; collectin sub-family member 12; K10062 collectin sub-family member 12 (A)	Phagosome (ko04145)	--	--	Collagen triple helix repeat (20 copies);; Lectin C-type domain	Collectin-12 GN=COLEC12 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: collectin-12 [Orycteropus afer afer]
ENSG00000158286(RNF207)	--	3.30017	250	3.06272	235	3.37818	261	2.51063	190	2.38501	180	2.88376	219	0.775081715	-0.423762894	normal	0.815873146	-0.403116719	normal	0.92715984	-0.259765031	normal	0.214545104	-0.36155759	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Cellular Component: intracellular (GO:0005622);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	"B-box zinc finger;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 207 GN=RNF207 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 207 [Odobenus rosmarus divergens]
ENSG00000158290(CUL4B)	--	27.68557059	2243	30.69068742	2429	31.56453089	2456	27.58861966	2227	24.45794795	1958	27.39084146	2216	0.987461505	-0.04113205	normal	0.902071913	-0.332177432	normal	0.980922362	-0.156542595	normal	0.351624737	-0.17638786	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	K10609|0|mcc:696410|CUL4B; cullin 4B; K10609 cullin 4 (A)	Nucleotide excision repair (ko03420);; Ubiquitin mediated proteolysis (ko04120)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cullin family;; Cullin protein neddylation domain	Cullin-4B GN=CUL4B OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cullin-4B isoform X3 [Mustela putorius furo] 
ENSG00000158292(GPR153)	--	3.444442	249	2.18389595	134	2.377972981	185	2.265541	153	3.011123	209	1.6255617	118	0.069591067	-0.727657704	normal	0.369607989	0.614250724	normal	0.322238222	-0.650317089	normal	0.688522978	-0.26441488	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08437|0|hsa:387509|GPR153, PGR1; G protein-coupled receptor 153; K08437 G protein-coupled receptor 153 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 153 GN=GPR153 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 153 [Tupaia chinensis]
ENSG00000158296(SLC13A3)	--	6.680304213	341	5.895984845	323	5.986201091	287	8.221665291	407	8.312700967	416	7.664670186	390	0.937975208	0.223502128	normal	0.852178816	0.34220772	normal	0.68949213	0.432171124	normal	0.168492753	0.329528697	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14445|0|pps:100976844|SLC13A3; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3; K14445 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2/3/5 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:sulfate symporter transmembrane region;; Citrate transporter	Solute carrier family 13 member 3 GN=SLC13A3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	Solute carrier family 13 member 3 [Tupaia chinensis]
ENSG00000158301(GPRASP2)	--	4.181471755	327	4.480114001	365	4.979820725	391	4.95255234	389	4.014101351	309	3.651273112	282	0.939722746	0.218704224	normal	0.921028192	-0.260541383	normal	0.555806515	-0.477579909	normal	0.580739191	-0.166204746	normal	--	--	--	--	--	--	--	Armadillo-like	G-protein coupled receptor-associated sorting protein 2 GN=GPRASP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor-associated sorting protein 2 isoform X3 [Lipotes vexillifer]
ENSG00000158315(RHBDL2)	--	0.084657393	3	0.3054862	7	0	0	2.184201282	65	3.320860303	86	2.9422912	71	3.80E-11	3.849254679	up	1.82E-12	3.342529509	up	5.55E-16	5.579366814	up	7.96E-16	4.448738667	up	[R]	General function prediction only	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	"K02857|0|hsa:54933|RHBDL2, RRP2; rhomboid, veinlet-like 2 (Drosophila) (EC:3.4.21.105); K02857 rhomboid-related protein 1/2/3 [EC:3.4.21.105] (A)"	--	[T]	Signal transduction mechanisms	Rhomboid family	"Rhomboid-related protein 2, C-terminal fragment GN=RHBDL2 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: rhomboid-related protein 2 isoform X5 [Canis lupus familiaris] 
ENSG00000158321(AUTS2)	--	3.018843795	290	2.01596527	246	5.155364191	270	4.22472466	510	6.093469292	588	4.382887052	465	0.00430081	0.780455995	normal	1.88E-08	1.23068811	up	0.006289878	0.772642677	normal	5.73E-07	0.934161244	normal	--	--	--	--	--	--	--	Autism susceptibility gene 2 protein	Autism susceptibility gene 2 protein GN=AUTS2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: autism susceptibility gene 2 protein isoform 1 [Ceratotherium simum simum]
ENSG00000158352(SHROOM4)	--	0	0	0	0	0	0	0.007361811	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18625|0|hsa:57477|SHROOM4, SHAP; shroom family member 4; K18625 protein Shroom (A)"	Tight junction (ko04530)	--	--	Apx/Shroom domain ASD2;; PDZ domain (Also known as DHR or GLGF)	Protein Shroom4 GN=SHROOM4 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: protein Shroom4 [Ceratotherium simum simum]
ENSG00000158373(HIST1H2BD)	--	20.392039	352	17.239025	405	18.148896	347	13.481636	261	16.76708006	278	21.082383	372	0.628516311	-0.460016236	normal	0.278861844	-0.561715992	normal	0.965103382	0.091689515	normal	0.239088943	-0.297531776	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|2.78852e-62|umr:103665052|histone H2B type 1-M; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-D GN=HIST1H2BD OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2B type 1-M-like [Mustela putorius furo]
ENSG00000158402(CDC25C)	--	8.23180387	271	7.899445109	242	7.746895985	242	6.688617509	237	5.283548114	174	5.647327015	206	0.939990263	-0.222885495	normal	0.638440077	-0.493690248	normal	0.936412633	-0.239033288	normal	0.299586667	-0.313045265	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Cellular Component: intracellular (GO:0005622);; Biological Process: protein dephosphorylation (GO:0006470);; Biological Process: positive regulation of cell cycle G2/M phase transition (GO:1902751);; 	"K05867|0|hsa:995|CDC25C, CDC25, PPP1R60; cell division cycle 25C (EC:3.1.3.48); K05867 M-phase inducer phosphatase 3 [EC:3.1.3.48] (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914);; MicroRNAs in cancer (ko05206)	[D]	"Cell cycle control, cell division, chromosome partitioning"	M-phase inducer phosphatase;; Rhodanese-like domain	M-phase inducer phosphatase 3 GN=CDC25C OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: M-phase inducer phosphatase 3 isoform 1 [Ceratotherium simum simum]
ENSG00000158406(HIST1H4H)	--	27.07526419	555	11.68456621	383	13.056102	324	7.406313436	145	6.597306	153	8.979492	200	0	-1.955844468	down	1.59E-08	-1.336587687	down	0.056630507	-0.700085258	normal	0.00171347	-1.362256186	down	[B]	Chromatin structure and dynamics	--	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000158411(MITD1)	--	17.401591	238	18.065866	243	16.58179362	229	12.305417	170	15.852041	210	12.050103	166	0.590203298	-0.512325272	normal	0.937703484	-0.230449189	normal	0.709738724	-0.468803545	normal	0.172305283	-0.400146335	normal	--	--	--	--	--	[S]	Function unknown	MIT (microtubule interacting and transport) domain	MIT domain-containing protein 1 GN=MITD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MIT domain-containing protein 1 [Loxodonta africana]
ENSG00000158417(EIF5B)	--	38.07762104	4522	38.4747419	4528	40.9493188	4765	29.824038	3547	26.365748	3147	25.474813	2982	0.863365743	-0.381047321	normal	0.236690967	-0.546103255	normal	0.008327097	-0.684210322	normal	0.000247023	-0.535397949	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K03243|0|mcc:714129|EIF5B; eukaryotic translation initiation factor 5B; K03243 translation initiation factor 5B (A)	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Translation-initiation factor 2;; Elongation factor Tu domain 2;; Elongation factor Tu domain 4;; 50S ribosome-binding GTPase	Eukaryotic translation initiation factor 5B GN=EIF5B OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 5B [Odobenus rosmarus divergens]
ENSG00000158423(RIBC1)	--	0.978087003	38	0.454560649	15	0.455459573	17	0.6696869	22	0.4654078	16	0.61431	20	0.906008189	-0.777512927	normal	--	--	--	0.988395162	0.209016428	normal	0.794544555	-0.293453109	normal	--	--	--	--	--	--	--	RIB43A	RIB43A-like with coiled-coils protein 1 GN=RIBC1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: RIB43A-like with coiled-coils protein 1 isoform 2 [Dasypus novemcinctus] 
ENSG00000158427(TMSB15B)	--	0.844514486	19	0.71989137	13	1.287704722	24	0.416016	18	0.307069663	11	0.536520068	16	--	--	--	--	--	--	0.977509846	-0.550512402	normal	--	--	--	--	--	--	--	--	[N]	Cell motility	--	Thymosin beta-15B GN=TMSB15B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: thymosin beta-15A-like [Sus scrofa] 
ENSG00000158428(CATIP)	--	0.215748	5	0.042185	1	0.206949	4	0.0856058	2	0.0841176	1	0.128117	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Ciliogenesis-associated TTC17-interacting protein GN=CATIP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C2orf62 homolog [Ceratotherium simum simum]
ENSG00000158435(CNOT11)	--	31.27133	1100	29.83448	1101	32.40178	1166	21.884885	833	24.498627	933	25.63268	942	0.613729139	-0.431252633	normal	0.933879845	-0.259903722	normal	0.887338137	-0.315603949	normal	0.046519194	-0.334922293	normal	--	--	Cellular Component: CCR4-NOT complex (GO:0030014);; 	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2363)	CCR4-NOT transcription complex subunit 11 GN=CNOT11 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: CCR4-NOT transcription complex subunit 11 [Orycteropus afer afer]
ENSG00000158445(KCNB1)	--	0.430599	85	1.22816667	96	0.732192305	88	0.193160785	20	0.119966807	17	0.308721629	27	1.58E-06	-2.035985131	down	2.55E-09	-2.417486185	down	0.000102643	-1.658503438	down	4.52E-07	-2.091871873	down	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated potassium channel activity (GO:0005249);; Biological Process: ion transport (GO:0006811);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: voltage-gated potassium channel complex (GO:0008076);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04885|0|ptr:469965|KCNB1; potassium voltage-gated channel, Shab-related subfamily, member 1; K04885 potassium voltage-gated channel Shab-related subfamily B member 1 (A)"	Taste transduction (ko04742)	[P]	Inorganic ion transport and metabolism	Kv2 voltage-gated K+ channel;; Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily B member 1 GN=KCNB1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily B member 1 [Felis catus]
ENSG00000158457(TSPAN33)	--	6.429259	293	4.588014	193	4.0256123	187	4.970965	208	6.544563	294	5.693585677	251	0.490834822	-0.521883705	normal	0.320502866	0.582068378	normal	0.793987294	0.413461671	normal	0.789634621	0.141156861	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17346|0|ptr:741446|TSPAN33; tetraspanin 33; K17346 tetraspanin-33 (A)	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-33 GN=TSPAN33 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetraspanin-33 isoform X1 [Galeopterus variegatus]
ENSG00000158458(NRG2)	--	2.959320971	201	2.916984925	192	3.784745446	254	2.06717614	123	1.571014057	102	1.489381689	96	0.115459303	-0.732138512	normal	0.009928094	-0.923809451	normal	1.19E-07	-1.397939344	down	0.000141307	-1.032697137	down	--	--	--	K05456|0|ptr:100613749|NRG2; neuregulin 2; K05456 neuregulin 2 (A)	ErbB signaling pathway (ko04012)	--	--	Neuregulin family;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Neuregulin-2 (Precursor) GN=NRG2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: pro-neuregulin-2, membrane-bound isoform isoform 1 [Orcinus orca]"
ENSG00000158467(AHCYL2)	--	8.069430865	641	6.334188451	506	6.836595853	546	6.44673555	500	7.264228583	587	9.991155885	785	0.752465217	-0.388171899	normal	0.95068203	0.192262679	normal	0.306385123	0.514305941	normal	0.789107122	0.125127549	normal	[H]	Coenzyme transport and metabolism	Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	K01251|0|ssc:100514931|AHCYL2; adenosylhomocysteinase-like 2; K01251 adenosylhomocysteinase [EC:3.3.1.1] (A)	Cysteine and methionine metabolism (ko00270)	[H]	Coenzyme transport and metabolism	"S-adenosyl-L-homocysteine hydrolase;; S-adenosyl-L-homocysteine hydrolase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain"	Putative adenosylhomocysteinase 3 GN=AHCYL2 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: putative adenosylhomocysteinase 3 isoformX1 [Sus scrofa]
ENSG00000158470(B4GALT5)	--	75.6116	5876	57.4559	4489	58.8942	4553	37.0677	2886	37.8948	2924	39.7763	3092	1.83E-08	-1.056192446	down	0.032993589	-0.639608174	normal	0.143528084	-0.566338848	normal	9.24E-05	-0.766004087	normal	--	--	--	"K09905|0|hsa:9334|B4GALT5, B4Gal-T5, BETA4-GALT-IV, beta4Gal-T5, beta4GalT-V, gt-V; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 (EC:2.4.1.38); K09905 beta-1,4-galactosyltransferase 5 [EC:2.4.1.-] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	N-terminal region of glycosyl transferase group 7;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	"Beta-1,4-galactosyltransferase 5 GN=B4GALT5 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-galactosyltransferase 5 [Orcinus orca] "
ENSG00000158473(CD1D)	--	0.0482588	2	0	0	0	0	0	0	0.0702765	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06448|0|hsa:912|CD1D, CD1A, R3; CD1d molecule; K06448 CD1 antigen (A)"	Hematopoietic cell lineage (ko04640);; Amoebiasis (ko05146)	--	--	Immunoglobulin C1-set domain	Antigen-presenting glycoprotein CD1d (Precursor) GN=CD1D OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: antigen-presenting glycoprotein CD1d isoform X1 [Equus przewalskii]
ENSG00000158480(SPATA2)	--	5.686306059	389	5.227983791	356	5.085876121	349	4.785846816	325	5.425616588	371	5.104299541	351	0.903191918	-0.28891222	normal	0.967483119	0.037957437	normal	0.968791986	-4.72E-05	normal	0.810300485	-0.084357528	normal	--	--	--	"K17595|0|hsa:9825|SPATA2, PD1, PPP1R145, tamo; spermatogenesis associated 2; K17595 spermatogenesis-associated protein 2 (A)"	--	--	--	--	Spermatogenesis-associated protein 2 GN=SPATA2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: spermatogenesis-associated protein 2 [Galeopterus variegatus]
ENSG00000158483(FAM86C1)	--	5.27351095	345	3.925067194	277	5.28460373	332	4.101818683	320	4.361184696	269	4.32206205	276	0.958915014	-0.138715055	normal	0.964694775	-0.063355347	normal	0.916025537	-0.273438315	normal	0.610064152	-0.162827057	normal	--	--	--	--	--	[R]	General function prediction only	Family of unknown function	Protein FAM86C1 GN=FAM86C1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM86A-like isoform X3 [Bubalus bubalis]
ENSG00000158486(DNAH3)	--	0.18154447	25	0.116156941	15	0.140794257	22	0.148198155	20	0.15957625	23	0.190254	27	0.984221815	-0.330034588	normal	0.97792261	0.550180788	normal	0.983995618	0.270363974	normal	0.896585106	0.155082619	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:55567|DNAH3, DLP3, DNAHC3B, HEL-36, Hsadhc3, dnahc3-b; dynein, axonemal, heavy chain 3; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D4;; ATP-binding dynein motor region D5;; Microtubule-binding stalk of dynein motor;; P-loop containing dynein motor region D3;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA);; RNA helicase"	"Dynein heavy chain 3, axonemal GN=DNAH3 OS=Homo sapiens (Human) PE=2 SV=1"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 3, axonemal [Equus caballus]"
ENSG00000158517(NCF1)	--	0	0	0.038511256	1	0	0	0.038566085	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K08011|0|hsa:653361|NCF1, NCF1A, NOXO2, SH3PXD1A, p47phox; neutrophil cytosolic factor 1; K08011 neutrophil cytosolic factor 1 (A)"	Chemokine signaling pathway (ko04062);; Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Leishmaniasis (ko05140)	[C]	Energy production and conversion	"SH3 domain;; NADPH oxidase subunit p47Phox, C terminal domain;; Variant SH3 domain;; Variant SH3 domain;; PX domain"	Neutrophil cytosol factor 1 GN=NCF1 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: neutrophil cytosol factor 1 [Galeopterus variegatus]
ENSG00000158525(CPA5)	--	0	0	0	0	0.040062702	0	0.313914517	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: carboxypeptidase activity (GO:0004180);; Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	K08781|0|hsa:93979|CPA5; carboxypeptidase A5 (EC:3.4.17.1); K08781 carboxypeptidase A5 [EC:3.4.17.1] (A)	--	[S]	Function unknown	Zinc carboxypeptidase;; Carboxypeptidase activation peptide	Carboxypeptidase A5 (Precursor) GN=CPA5 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: carboxypeptidase A5 [Panthera tigris altaica]
ENSG00000158526(TSR2)	--	26.2388	797	26.5057	836	25.3472	790	29.5832	904	27.7447	826	27.6432	838	0.966822471	0.150638	normal	0.976287756	-0.038717258	normal	0.974789529	0.076663641	normal	0.82211564	0.0623356	normal	--	--	--	"K14800|9.69003e-123|pps:100978182|TSR2; TSR2, 20S rRNA accumulation, homolog (S. cerevisiae); K14800 pre-rRNA-processing protein TSR2 (A)"	--	[S]	Function unknown	Pre-rRNA-processing protein TSR2	Pre-rRNA-processing protein TSR2 homolog GN=TSR2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pre-rRNA-processing protein TSR2 homolog isoform X2 [Tupaia chinensis]
ENSG00000158528(PPP1R9A)	--	5.33440955	1111	7.149280883	1330	5.849622143	1183	4.968743382	984	4.572435277	927	7.171329809	1217	0.957478285	-0.205658404	normal	0.201957486	-0.541469775	normal	0.981317565	0.032546631	normal	0.272543059	-0.233020751	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17551|0|hsa:55607|PPP1R9A, NRB1, NRBI, Neurabin-I; protein phosphatase 1, regulatory subunit 9A; K17551 neurabin (A)"	--	--	--	SAM domain (Sterile alpha motif);; PDZ domain (Also known as DHR or GLGF);; SAM domain (Sterile alpha motif)	Neurabin-1 GN=PPP1R9A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: neurabin-1 [Odobenus rosmarus divergens]
ENSG00000158545(ZC3H18)	--	19.3584858	1740	20.82641993	1899	22.44248401	2034	20.96079817	1886	19.20524867	1706	20.76543442	1853	0.98380784	0.085337719	normal	0.974178486	-0.175900937	normal	0.980115461	-0.142637085	normal	0.731003084	-0.080279413	normal	--	--	--	"K13092|0|hsa:124245|ZC3H18, NHN1; zinc finger CCCH-type containing 18; K13092 nuclear protein NHN1 (A)"	--	--	--	--	Zinc finger CCCH domain-containing protein 18 GN=ZC3H18 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger CCCH domain-containing protein 18 [Galeopterus variegatus]
ENSG00000158552(ZFAND2B)	--	7.577576282	165	7.029276346	157	7.657718387	166	6.490089151	139	8.656931198	166	5.817022145	130	0.933800272	-0.275415071	normal	0.965118283	0.058444613	normal	0.896040585	-0.357275665	normal	0.666230489	-0.187066518	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	AN1-like Zinc finger	AN1-type zinc finger protein 2B GN=ZFAND2B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: AN1-type zinc finger protein 2B isoform X1 [Mustela putorius furo] 
ENSG00000158553(POM121L2)	--	0.0167308	1	0	0	0	0	0.0339408	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K14316|0|hsa:94026|POM121L2, POM121-L, POM121L; POM121 transmembrane nucleoporin-like 2; K14316 nuclear pore complex protein Nup121 (A)"	RNA transport (ko03013)	--	--	POM121 family	POM121-like protein 2 GN=POM121L2 OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	PREDICTED: uncharacterized protein LOC101397466 [Ceratotherium simum simum]
ENSG00000158555(GDPD5)	--	2.153390933	149	2.0526159	147	1.841974962	126	2.6219436	180	3.696559145	250	4.242551974	295	0.94248933	0.239601901	normal	0.066622043	0.738793524	normal	2.90E-06	1.209234478	up	0.025179632	0.76075554	normal	[C]	Energy production and conversion	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; 	--	--	[C]	Energy production and conversion	Glycerophosphoryl diester phosphodiesterase family	Glycerophosphodiester phosphodiesterase domain-containing protein 5 GN=GDPD5 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 5 isoform X4 [Panthera tigris altaica]
ENSG00000158560(DYNC1I1)	--	0	0	0	0	0	0	0	0	0.171648725	1	0.122975177	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasmic dynein complex (GO:0005868);; Biological Process: microtubule-based movement (GO:0007018);; 	"K10415|0|tup:102470486|DYNC1I1; dynein, cytoplasmic 1, intermediate chain 1; K10415 dynein intermediate chain, cytosolic (A)"	Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Cytoplasmic dynein 1 intermediate chain 2;; WD domain, G-beta repeat"	Cytoplasmic dynein 1 intermediate chain 1 GN=DYNC1I1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: cytoplasmic dynein 1 intermediate chain 1 isoform X1 [Tupaia chinensis]
ENSG00000158571(PFKFB1)	--	0.329969082	10	0.285550184	10	0.1618209	5	0.0263633	1	0.040143194	0	0.054062089	2	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: 6-phosphofructo-2-kinase activity (GO:0003873);; Molecular Function: ATP binding (GO:0005524);; Biological Process: fructose metabolic process (GO:0006000);; 	"K01103|0|ggo:101140929|PFKFB1; 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase 1 isoform 1; K19028 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 1 [EC:2.7.1.105 3.1.3.46] (A)"	Fructose and mannose metabolism (ko00051);; HIF-1 signaling pathway (ko04066);; AMPK signaling pathway (ko04152)	[G]	Carbohydrate transport and metabolism	6-phosphofructo-2-kinase;; Histidine phosphatase superfamily (branch 1);; AAA domain;; Zeta toxin	"Fructose-2,6-bisphosphatase GN=PFKFB1 OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 isoform X5 [Ursus maritimus]"
ENSG00000158604(TMED4)	--	49.76781	1644	47.20825	1575	48.71375	1600	45.21097	1497	42.78436	1404	42.82667	1410	0.973877688	-0.165805869	normal	0.968831045	-0.187045102	normal	0.968469186	-0.190476265	normal	0.33942079	-0.182099524	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 4 (Precursor) GN=TMED4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 4 [Tupaia chinensis]
ENSG00000158615(PPP1R15B)	--	19.79461	1562	21.28230896	1571	19.52763937	1502	19.273349	1489	19.225435	1484	21.3334321	1671	0.980930345	-0.099782419	normal	0.98031692	-0.1035161	normal	0.977022414	0.145396628	normal	0.955665903	-0.018133529	normal	--	--	--	"K17558|0|hsa:84919|PPP1R15B, CREP; protein phosphatase 1, regulatory subunit 15B; K17558 protein phosphatase 1 regulatory subunit 15B (A)"	--	--	--	eIF2-alpha phosphatase phosphorylation constitutive repressor;; Phosphatase-1 catalytic subunit binding region	Protein phosphatase 1 regulatory subunit 15B GN=PPP1R15B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 15B [Galeopterus variegatus]
ENSG00000158623(COPG2)	--	16.4915	960	14.0599	818	14.493219	834	15.014465	876	18.1324	1046	14.628756	848	0.965815799	-0.162663132	normal	0.864669616	0.332738358	normal	0.97751486	0.015697211	normal	0.815579992	0.063474216	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: COPI vesicle coat (GO:0030126);; 	"K17267|0|cjc:100414060|COPG2; coatomer protein complex, subunit gamma 2; K17267 coatomer protein complex, subunit gamma (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptin N terminal region;; Coatomer gamma subunit appendage platform subdomain;; HEAT repeats;; HEAT-like repeat;; HEAT repeat;; non-SMC mitotic condensation complex subunit 1	Coatomer subunit gamma-2 GN=COPG2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit gamma-2 [Tupaia chinensis]
ENSG00000158636(EMSY)	--	6.24800833	591	6.56217723	560	6.85656034	588	6.077131441	567	6.142749144	585	5.079528197	506	0.969516663	-0.090401685	normal	0.971763545	0.041473658	normal	0.94020906	-0.224347585	normal	0.753839695	-0.090242282	normal	--	--	--	--	--	[R]	General function prediction only	ENT domain	Protein EMSY GN=EMSY OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein EMSY isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000158639(PAGE5)	--	0.17762124	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GAGE protein	P antigen family member 5 GN=PAGE5 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: putative G antigen family E member 3-like [Equus caballus]
ENSG00000158669(GPAT4)	--	25.30074616	2148	24.91735646	2144	24.898976	2145	35.49218	3032	32.95130334	2930	32.36491793	2887	0.531688025	0.466161629	normal	0.704833182	0.42890946	normal	0.717985858	0.420045849	normal	0.003255752	0.437785759	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13506|0|hsa:137964|AGPAT6, 1-AGPAT_6, LPAAT-zeta, LPAATZ, TSARG7; 1-acylglycerol-3-phosphate O-acyltransferase 6 (EC:2.3.1.15); K13506 glycerol-3-phosphate O-acyltransferase 3/4 [EC:2.3.1.15] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	Glycerol-3-phosphate acyltransferase 4 (Precursor) GN=AGPAT6 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: glycerol-3-phosphate acyltransferase 6 isoform X1 [Ursus maritimus]
ENSG00000158683(PKD1L1)	--	0.313631728	5	0.067012057	12	0.027607455	4	0.172788272	4	0.01091496	1	0.016708161	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04987|0|hsa:168507|PKD1L1, PRO19563; polycystic kidney disease 1 like 1; K04987 polycystin 1L1 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	REJ domain;; Polycystin cation channel;; PLAT/LH2 domain;; PKD domain	Polycystic kidney disease protein 1-like 1 GN=PKD1L1 OS=Homo sapiens (Human) PE=1 SV=1	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: polycystic kidney disease protein 1-like 1 [Equus przewalskii]
ENSG00000158691(ZSCAN12)	--	2.705720274	357	2.494132731	338	2.148343752	308	2.049333	260	2.31135987	313	2.488576835	324	0.547424887	-0.485783363	normal	0.958949563	-0.131674732	normal	0.966332761	0.064463393	normal	0.54775489	-0.181836961	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger and SCAN domain-containing protein 12 GN=ZSCAN12 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 12 [Galeopterus variegatus]
ENSG00000158710(TAGLN2)	--	308.7065084	7124	356.9109351	8305	312.0512342	7357	503.409234	11590	459.3922071	10461	391.1409739	9042	0.01889525	0.671174371	normal	0.970624071	0.311491503	normal	0.974587015	0.289179176	normal	0.009648549	0.426396292	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Calponin homology (CH) domain;; Calponin family repeat	Transgelin-2 GN=TAGLN2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: transgelin-2 isoform X1 [Myotis lucifugus]
ENSG00000158711(ELK4)	--	6.59592	849	7.190839002	961	5.74169293	805	6.152432	876	5.858347	855	6.182546	849	0.977742478	0.014308561	normal	0.959248164	-0.189721825	normal	0.975503466	0.068359268	normal	0.892283724	-0.040956982	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K04376|0|hsa:2005|ELK4, SAP1; ELK4, ETS-domain protein (SRF accessory protein 1); K04376 ETS domain-containing protein Elk-4 (A)"	MAPK signaling pathway (ko04010);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Ets-domain	ETS domain-containing protein Elk-4 GN=ELK4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: ETS domain-containing protein Elk-4 [Capra hircus]
ENSG00000158714(SLAMF8)	--	0.095179537	5	0.152444907	8	0.056561495	2	0.076572256	4	0.223169	11	0.113174006	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16853|1.51988e-175|hsa:56833|SLAMF8, BLAME, CD353, SBBI42; SLAM family member 8; K16853 SLAM family member 8 (A)"	--	--	--	Immunoglobulin domain	SLAM family member 8 (Precursor) GN=SLAMF8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SLAM family member 8 [Galeopterus variegatus]
ENSG00000158715(SLC45A3)	--	3.885531687	223	2.511832	149	3.716711	210	4.632086	267	4.521725	252	2.399858	139	0.938933335	0.22752966	normal	0.072868852	0.730919387	normal	0.401054636	-0.598262359	normal	0.814196428	0.154512402	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K15379|0|hsa:85414|SLC45A3, IPCA-2, IPCA-6, IPCA-8, IPCA6, PCANAP2, PCANAP6, PCANAP8, PRST; solute carrier family 45, member 3; K15379 solute carrier family 45, member 3 (A)"	Transcriptional misregulation in cancer (ko05202);; MicroRNAs in cancer (ko05206)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; MFS/sugar transport protein	Solute carrier family 45 member 3 GN=SLC45A3 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 45 member 3 [Galeopterus variegatus]
ENSG00000158716(DUSP23)	--	49.78724	385	56.05994	450	49.38106	405	46.905	384	55.74373	434	47.174438	376	0.968854656	-0.034446752	normal	0.967348818	-0.073405301	normal	0.963241333	-0.11503477	normal	0.824138446	-0.075802868	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14165|5.31828e-93|ptr:746364|DUSP23; dual specificity phosphatase 23; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Inositol hexakisphosphate;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 23 GN=DUSP23 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 23 isoform X1 [Galeopterus variegatus]
ENSG00000158717(RNF166)	--	10.7505354	349	12.0719566	370	11.19126099	372	11.45702736	369	12.64318581	379	11.80807282	393	0.967787282	0.049350223	normal	0.968279703	0.013192743	normal	0.967177442	0.070655766	normal	0.910151281	0.043702697	normal	[T]	Signal transduction mechanisms	Molecular Function: metal ion binding (GO:0046872);; 	K17044|4.99249e-163|ptr:468071|RNF166; ring finger protein 166; K17044 RING finger protein 166 (A)	--	--	--	"Drought induced 19 protein (Di19), zinc-binding;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Rubredoxin"	RING finger protein 166 GN=RNF166 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 166 isoform 1 [Trichechus manatus latirostris]
ENSG00000158747(NBL1)	--	30.22697194	1543	28.31693222	1553	32.08504282	1688	39.00778287	2037	37.97922835	1795	32.68414534	1725	0.826387197	0.369554519	normal	0.970806817	0.187329665	normal	0.985231351	0.022969659	normal	0.290549745	0.19452222	normal	--	--	--	--	--	--	--	DAN domain;; Cystine-knot domain	Neuroblastoma suppressor of tumorigenicity 1 (Precursor) GN=NBL1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: neuroblastoma suppressor of tumorigenicity 1 isoform X1 [Myotis brandtii]
ENSG00000158748(HTR6)	--	0.708483991	37	0.318247163	11	0.88244189	36	0.21268583	11	0.274878094	8	0.111683645	5	0.104640717	-1.648421883	normal	--	--	--	0.001065436	-2.533288645	down	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04162|0|hsa:3362|HTR6, 5-HT6, 5-HT6R; 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled; K04162 5-hydroxytryptamine receptor 6 (A)"	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Serotonergic synapse (ko04726)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	5-hydroxytryptamine receptor 6 GN=HTR6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 5-hydroxytryptamine receptor 6 [Camelus bactrianus]
ENSG00000158769(F11R)	--	17.11013097	1408	12.39234668	1020	13.7930755	1118	25.8837	1967	28.02415617	2177	21.07055503	1726	0.558653855	0.451099204	normal	4.51E-08	1.07123343	up	0.040234868	0.617543396	normal	0.000149163	0.705614639	normal	--	--	--	K06089|0|ptr:469555|F11R; F11 receptor; K06089 junctional adhesion molecule 1 (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670)	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin C1-set domain;; CD80-like C2-set immunoglobulin domain	Junctional adhesion molecule A (Precursor) GN=F11R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: junctional adhesion molecule A [Galeopterus variegatus]
ENSG00000158773(USF1)	--	15.81680604	581	16.5148974	624	17.93930652	686	18.29144038	668	20.97819515	779	18.93899624	709	0.958510265	0.170058038	normal	0.897361319	0.298003219	normal	0.974805888	0.039200602	normal	0.466646442	0.168482987	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09106|0|pps:100985851|USF1; upstream transcription factor 1; K09106 upstream stimulatory factor (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Upstream stimulatory factor 1 GN=USF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: upstream stimulatory factor 1 isoform X1 [Galeopterus variegatus]
ENSG00000158792(SPATA2L)	--	8.279298704	349	7.652821001	312	7.299669	308	7.962415	309	6.437015	254	5.48670943	226	0.944090873	-0.205490255	normal	0.887305431	-0.316440788	normal	0.679691607	-0.452295848	normal	0.226795781	-0.31874673	normal	--	--	--	"K17595|0|hsa:124044|SPATA2L, C16orf76, tamo; spermatogenesis associated 2-like; K17595 spermatogenesis-associated protein 2 (A)"	--	--	--	--	Spermatogenesis-associated protein 2-like protein GN=SPATA2L OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: spermatogenesis-associated protein 2-like protein [Galeopterus variegatus]
ENSG00000158793(NIT1)	--	21.407111	489	23.09819402	541	23.956828	552	18.945013	435	19.56968656	436	18.34534391	423	0.947430055	-0.19898793	normal	0.858852843	-0.331691941	normal	0.753971368	-0.391074377	normal	0.150146469	-0.311068609	normal	[R]	General function prediction only	"Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; "	--	--	[E]	Amino acid transport and metabolism	Carbon-nitrogen hydrolase	Nitrilase homolog 1 GN=NIT1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: nitrilase homolog 1 isoform X2 [Oryctolagus cuniculus]
ENSG00000158796(DEDD)	--	13.75875383	535	14.24864103	519	15.44546593	573	13.13904656	525	15.49556521	593	14.5338116	555	0.970831607	-0.057885911	normal	0.956476107	0.170406226	normal	0.97179673	-0.054193471	normal	0.96328771	0.019408278	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	--	--	--	--	Death effector domain	Death effector domain-containing protein GN=DEDD OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: death effector domain-containing protein isoform 1 [Ceratotherium simum simum]
ENSG00000158805(ZNF276)	--	3.174863	582	3.2765583	628	3.0830093	573	3.305349063	605	3.753179	663	3.896506	598	0.973263708	0.025018946	normal	0.972496285	0.056684897	normal	0.97225352	0.053181502	normal	0.892100274	0.044359941	normal	[R]	General function prediction only	Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger associated domain (zf-AD);; Zinc-finger double domain"	Zinc finger protein 276 GN=ZNF276 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: zinc finger protein 276 isoform X2 [Canis lupus familiaris]
ENSG00000158806(NPM2)	--	0	0	0.103323984	2	0.2980414	0	0.291903937	1	0.113223309	1	0.053228967	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K11277|4.40271e-112|hsa:10361|NPM2; nucleophosmin/nucleoplasmin 2; K11277 nucleophosmin 2 (A)	--	--	--	Nucleoplasmin	Nucleoplasmin-2 GN=NPM2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nucleoplasmin-2 [Loxodonta africana]
ENSG00000158813(EDA)	--	2.126416703	125	0.935909125	59	1.878139635	82	0.455998453	30	0.923730793	49	0.341762602	25	4.84E-09	-2.034354033	down	0.965527339	-0.281431827	normal	0.000197136	-1.663307201	down	0.033092804	-1.376204928	normal	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	K05480|1.39261e-129|ocu:100340021|EDA; ectodysplasin A; K05480 ectodysplasin-A (A)	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNF(Tumour Necrosis Factor) family;; Collagen triple helix repeat (20 copies)	"Ectodysplasin-A, secreted form GN=EDA OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: ectodysplasin-A isoform X1 [Oryctolagus cuniculus]
ENSG00000158815(FGF17)	--	0	0	0.133828071	4	0	0	0	0	0.066246226	1	0.03358082	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|9.76561e-134|pps:100982572|FGF17; fibroblast growth factor 17; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 17 (Precursor) GN=FGF17 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 17 [Physeter catodon]
ENSG00000158825(CDA)	--	13.42234	189	8.927053	128	10.534054	153	37.01516	530	32.23336	452	33.67534	482	2.04E-11	1.44943808	up	2.33E-15	1.786786904	up	7.93E-14	1.637593075	up	1.03E-16	1.617661557	up	[F]	Nucleotide transport and metabolism	Molecular Function: cytidine deaminase activity (GO:0004126);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: cytidine deamination (GO:0009972);; 	K01489|1.77886e-105|ptr:744046|CDA; cytidine deaminase; K01489 cytidine deaminase [EC:3.5.4.5] (A)	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Cytidine and deoxycytidylate deaminase zinc-binding region;; Cytidine and deoxycytidylate deaminase zinc-binding region	Cytidine deaminase GN=CDA OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: cytidine deaminase [Ceratotherium simum simum]
ENSG00000158828(PINK1)	--	24.3593	1222	18.478	953	23.7869	1226	28.7527	1448	30.6039	1529	29.3639	1478	0.959800237	0.21373796	normal	0.01918749	0.659779952	normal	0.940175778	0.261102115	normal	0.02040636	0.368634166	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05688|0|hsa:65018|PINK1, BRPK, PARK6; PTEN induced putative kinase 1 (EC:2.7.11.1); K05688 PTEN induced putative kinase 1 [EC:2.7.11.1] (A)"	Parkinson's disease (ko05012)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	"Serine/threonine-protein kinase PINK1, mitochondrial (Precursor) GN=PINK1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: serine/threonine-protein kinase PINK1, mitochondrial [Eptesicus fuscus]"
ENSG00000158850(B4GALT3)	--	13.7759	490	13.43929	476	15.804182	559	14.67688	505	13.8355	486	12.48895	449	0.971611664	0.012630365	normal	0.970618124	0.008541327	normal	0.867254581	-0.323445884	normal	0.721808438	-0.10399882	normal	--	--	--	"K07968|0|hsa:8703|B4GALT3, beta4Gal-T3; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 (EC:2.4.1.90 2.4.1.38); K07968 beta-1,4-galactosyltransferase 3 [EC:2.4.1.90 2.4.1.38 2.4.1.-] (A)"	N-Glycan biosynthesis (ko00510);; Other types of O-glycan biosynthesis (ko00514);; Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	N-terminal region of glycosyl transferase group 7;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	"Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase GN=B4GALT3 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,4-galactosyltransferase 3 isoform X1 [Leptonychotes weddellii] "
ENSG00000158856(DMTN)	--	22.0362324	1132	23.56379107	1094	23.77158813	1221	34.48313899	1673	33.54408087	1656	42.78383149	2200	0.210642214	0.532133761	normal	0.11102738	0.576011904	normal	8.41E-05	0.840362464	normal	0.00239652	0.661465619	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Villin headpiece domain	Dematin GN=DMTN OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: dematin isoform X1 [Pteropus alecto] 
ENSG00000158859(ADAMTS4)	--	0.00517715	1	0.00507285	1	0	0	0	0	0	0	0.010271909	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K07764|0|hsa:9507|ADAMTS4, ADAMTS-2, ADAMTS-4, ADMP-1; ADAM metallopeptidase with thrombospondin type 1 motif, 4 (EC:3.4.24.82); K07764 a disintegrin and metalloproteinase with thrombospondin motifs 4 [EC:3.4.24.82] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Thrombospondin type 1 domain;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 4 (Precursor) GN=ADAMTS4 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 4 [Ceratotherium simum simum]
ENSG00000158863(FAM160B2)	--	17.7566571	1346	17.8720145	1279	16.86559155	1297	17.61483834	1322	21.19987317	1549	17.0515694	1270	0.981728431	-0.056723161	normal	0.945292676	0.254620405	normal	0.981925997	-0.038595945	normal	0.825692209	0.057170752	normal	--	--	--	--	--	[S]	Function unknown	Retinoic acid induced 16-like protein	Protein FAM160B2 GN=FAM160B2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM160B2 [Lipotes vexillifer]
ENSG00000158864(NDUFS2)	--	51.72109041	1995	49.83733034	1963	49.09175897	1922	46.56086207	1804	48.99657086	1869	45.10780034	1738	0.975200293	-0.175879145	normal	0.983711579	-0.092147398	normal	0.97801877	-0.153344754	normal	0.48846016	-0.141238869	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity, acting on NAD(P)H (GO:0016651);; Molecular Function: quinone binding (GO:0048038);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K03935|0|ptr:747334|NDUFS2; NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3); K03935 NADH dehydrogenase (ubiquinone) Fe-S protein 2 [EC:1.6.5.3 1.6.99.3] (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"Respiratory-chain NADH dehydrogenase, 49 Kd subunit"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial (Precursor) GN=NDUFS2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial precursor [Camelus ferus]"
ENSG00000158865(SLC5A11)	--	0.030750462	1	0.06046041	2	0.147430077	0	0.105482019	5	0.076224386	2	0.091196664	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14391|0|mcf:101866260|uncharacterized LOC101866260; K14391 solute carrier family 5 (sodium/myo-inositol cotransporter), member 11 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium/myo-inositol cotransporter 2 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/myo-inositol cotransporter 2 isoform 1 [Ceratotherium simum simum]
ENSG00000158869(FCER1G)	--	0	0	0	0	0	0	0.159641	1	0.482443	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07983|7.01792e-26|mcf:102120026|FCER1G, FcRgamma; Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide; K07983 Fc receptor, IgE, high affinity I, gamma polypeptide (A)"	Sphingolipid signaling pathway (ko04071);; Platelet activation (ko04611);; Natural killer cell mediated cytotoxicity (ko04650);; Fc epsilon RI signaling pathway (ko04664);; Tuberculosis (ko05152);; Asthma (ko05310)	--	--	T-cell surface glycoprotein CD3 zeta chain	High affinity immunoglobulin epsilon receptor subunit gamma (Precursor) GN=FCER1G OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: high affinity immunoglobulin epsilon receptor subunit gamma [Felis catus]
ENSG00000158882(TOMM40L)	--	3.952279	200	3.702758347	188	4.921686001	246	5.9821882	297	5.837355331	282	4.5024907	223	0.449950847	0.536230834	normal	0.402558621	0.559835942	normal	0.957175348	-0.148943929	normal	0.275555364	0.317582101	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: transmembrane transport (GO:0055085);; 	K11518|0|mcf:101925730|hypothetical protein; K11518 mitochondrial import receptor subunit TOM40 (A)	Amyotrophic lateral sclerosis (ALS) (ko05014)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Eukaryotic porin	Mitochondrial import receptor subunit TOM40B GN=TOMM40L OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import receptor subunit TOM40B isoformX1 [Equus caballus] 
ENSG00000158887(MPZ)	--	0.071760007	2	0.114572305	2	0.029901641	0	0.220108587	6	0.177498392	5	0.060598201	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06770|1.58994e-131|nle:100606740|MPZ; myelin protein zero; K06770 myelin protein zero (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Myelin-PO cytoplasmic C-term p65 binding region;; Immunoglobulin V-set domain;; Immunoglobulin domain	Myelin protein P0 (Precursor) GN=MPZ OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: myelin protein P0 [Vicugna pacos]
ENSG00000158941(CCAR2)	--	50.97837886	3027	57.56087526	3274	78.1684771	3195	65.87261072	2969	79.02087029	3463	70.18848988	3029	0.989529282	-0.058713753	normal	0.99011012	0.059514777	normal	0.988984467	-0.085224359	normal	0.926926189	-0.026371689	normal	--	--	--	--	--	--	--	DBC1;; S1-like	Cell cycle and apoptosis regulator protein 2 GN=CCAR2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cell cycle and apoptosis regulator protein 2 [Galeopterus variegatus] 
ENSG00000158966(CACHD1)	--	1.366244695	158	1.43512711	160	1.467248	162	1.15851185	132	1.777645098	203	1.200113099	139	0.931469271	-0.287158864	normal	0.904840273	0.319296567	normal	0.947462097	-0.226911237	normal	0.950946588	-0.038953029	normal	--	--	--	--	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	VWA N-terminal;; Cache domain;; von Willebrand factor type A domain	VWFA and cache domain-containing protein 1 (Precursor) GN=CACHD1 OS=Homo sapiens (Human) PE=2 SV=2	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: VWFA and cache domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000158985(CDC42SE2)	--	27.9415443	1440	30.48443239	1580	25.70482366	1314	31.382754	1647	27.46000458	1418	33.04208304	1710	0.974066702	0.162777001	normal	0.970885202	-0.177314328	normal	0.812782105	0.371363913	normal	0.580739191	0.118393381	normal	--	--	--	--	--	--	--	P21-Rho-binding domain	CDC42 small effector protein 2 GN=CDC42SE2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	CDC42 small effector protein 2 [Bos taurus] 
ENSG00000158987(RAPGEF6)	--	17.17298003	2020	24.22674648	2733	17.54949404	2004	16.61311381	1962	16.60532886	1908	23.95987607	2674	0.985397632	-0.072806321	normal	0.22375534	-0.539491489	normal	0.751226826	0.407558376	normal	0.895327936	-0.066853533	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K08020|0|hsa:51735|RAPGEF6, KIA001LB, PDZ-GEF2, PDZGEF2, RA-GEF-2, RAGEF2; Rap guanine nucleotide exchange factor (GEF) 6; K08020 Rap guanine nucleotide exchange factor 6 (A)"	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; PDZ domain (Also known as DHR or GLGF);; Ras association (RalGDS/AF-6) domain;; Cyclic nucleotide-binding domain	Rap guanine nucleotide exchange factor 6 GN=RAPGEF6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rap guanine nucleotide exchange factor 6 isoform X1 [Leptonychotes weddellii]
ENSG00000159023(EPB41)	--	5.351230917	585	4.953863449	530	5.4719166	594	5.8624799	628	4.853874883	552	7.398959021	670	0.971503907	0.071314883	normal	0.971284055	0.037145493	normal	0.959966397	0.165010944	normal	0.738761705	0.093453054	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: cytoskeleton (GO:0005856);; Molecular Function: cytoskeletal protein binding (GO:0008092);; Biological Process: cortical actin cytoskeleton organization (GO:0030866);; 	"K06107|0|hsa:2035|EPB41, 4.1R, EL1, HE; erythrocyte membrane protein band 4.1; K06107 erythrocyte membrane protein band 4.1 (A)"	Tight junction (ko04530)	[R]	General function prediction only	4.1 protein C-terminal domain (CTD);; SAB domain;; FERM C-terminal PH-like domain;; FERM N-terminal domain;; FERM central domain;; FERM adjacent (FA)	Protein 4.1 GN=EPB41 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: protein 4.1 isoform X4 [Canis lupus familiaris]
ENSG00000159063(ALG8)	--	51.06921019	984	57.85349675	1101	52.56451515	1002	53.93387004	1068	50.56088835	982	47.15828392	938	0.976869428	0.087218427	normal	0.962582685	-0.186175142	normal	0.974910232	-0.103352868	normal	0.792657495	-0.068713567	normal	--	--	"Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K03849|0|ggo:101143793|ALG8; probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase isoform 1; K03849 alpha-1,3-glucosyltransferase [EC:2.4.1.265] (A)"	N-Glycan biosynthesis (ko00510)	[K]	Transcription	"ALG6, ALG8 glycosyltransferase family"	"Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase GN=ALG8 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase [Vicugna pacos]"
ENSG00000159069(FBXW5)	--	36.98464973	1500	31.723307	1221	34.584591	1358	37.18509154	1508	43.60638026	1694	44.35896565	1760	0.983910972	-0.023134702	normal	0.573679687	0.450468523	normal	0.826944503	0.365442076	normal	0.127356123	0.262044944	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10263|0|hsa:54461|FBXW5, Fbw5; F-box and WD repeat domain containing 5; K10263 F-box and WD-40 domain protein 5 (A)"	--	--	--	"WD domain, G-beta repeat;; F-box-like;; F-box domain"	F-box/WD repeat-containing protein 5 GN=FBXW5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/WD repeat-containing protein 5 isoform X1 [Galeopterus variegatus]
ENSG00000159079(C21orf59)	--	19.47269216	605	19.20345041	572	21.78690574	650	19.07726278	589	20.44106933	592	19.28428531	588	0.971465339	-0.069321339	normal	0.972358414	0.028082491	normal	0.962192354	-0.152541688	normal	0.822709815	-0.067537272	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2870)	UPF0769 protein C21orf59 GN=C21orf59 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0769 protein C21orf59 homolog [Galeopterus variegatus]
ENSG00000159082(SYNJ1)	--	2.061674375	174	1.752576996	165	1.532393907	171	1.603131462	189	1.621681913	191	1.623108015	191	0.964396898	0.08772334	normal	0.951173535	0.188076784	normal	0.958386902	0.150028874	normal	0.739939017	0.141870554	normal	--	--	Molecular Function: phosphoric ester hydrolase activity (GO:0042578);; 	K01099|0|cjc:100395303|SYNJ1; synaptojanin 1; K01099 phosphatidylinositol-bisphosphatase [EC:3.1.3.36] (A)	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SacI homology domain;; Domain of unknown function (DUF1866);; Endonuclease/Exonuclease/phosphatase family	Synaptojanin-1 GN=SYNJ1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: synaptojanin-1 isoform 1 [Ceratotherium simum simum]
ENSG00000159086(PAXBP1)	--	9.935797024	1041	11.63431441	1181	9.2471844	963	9.917482957	1001	10.728045	1052	10.35290303	1016	0.976821955	-0.087229051	normal	0.963388205	-0.188045512	normal	0.977671116	0.068895913	normal	0.767869335	-0.07492046	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K13211|0|pps:100990314|PAXBP1, GCFC1; PAX3 and PAX7 binding protein 1; K13211 GC-rich sequence DNA-binding factor (A)"	--	[K]	Transcription	GC-rich sequence DNA-binding factor-like protein	PAX3- and PAX7-binding protein 1 GN=PAXBP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: GC-rich sequence DNA-binding factor 1 [Ceratotherium simum simum]
ENSG00000159110(IFNAR2)	--	30.8749092	1370	30.1725253	1432	28.3499099	1354	27.72529119	1297	26.63519326	1339	31.74395015	1613	0.978446824	-0.109703205	normal	0.977814771	-0.118172997	normal	0.951104432	0.243977296	normal	0.976471761	0.011313831	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05131|0|ptr:473965|IFNAR2; interferon (alpha, beta and omega) receptor 2; K05131 interferon receptor 2 (A)"	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	"Tissue factor;; Interferon-alpha/beta receptor, fibronectin type III"	Interferon alpha/beta receptor 2 (Precursor) GN=IFNAR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interferon alpha/beta receptor 2 [Ceratotherium simum simum]
ENSG00000159111(MRPL10)	--	47.642564	1384	38.67181604	1131	42.05801121	1228	42.15676346	1225	43.2988021	1241	46.51730375	1353	0.961512089	-0.20665041	normal	0.976262778	0.112334202	normal	0.975832995	0.131405614	normal	0.984925516	0.008103987	normal	[J]	"Translation, ribosomal structure and biogenesis"	Cellular Component: intracellular (GO:0005622);; Biological Process: ribosome biogenesis (GO:0042254);; 	K02864|4.70466e-154|mcf:102142919|MRPL10; mitochondrial ribosomal protein L10; K02864 large subunit ribosomal protein L10 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L10;; Putative binding domain	"39S ribosomal protein L10, mitochondrial (Precursor) GN=MRPL10 OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L10, mitochondrial [Erinaceus europaeus]"
ENSG00000159128(IFNGR2)	--	27.57282	869	28.77555	908	28.5299762	958	22.0206971	729	19.61402	643	22.70779	740	0.910781888	-0.283721072	normal	0.296545028	-0.518268871	normal	0.769845105	-0.380107135	normal	0.021181993	-0.394005055	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05133|0|pps:100988947|IFNGR2; interferon gamma receptor 2 (interferon gamma transducer 1); K05133 interferon gamma receptor 2 (A)	Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; Osteoclast differentiation (ko04380);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; Salmonella infection (ko05132);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Inflammatory bowel disease (IBD) (ko05321)	--	--	"Tissue factor;; Interferon-alpha/beta receptor, fibronectin type III;; Fibronectin type III domain"	Interferon gamma receptor 2 (Precursor) GN=IFNGR2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: interferon gamma receptor 2-like isoform X3 [Canis lupus familiaris]
ENSG00000159131(GART)	--	43.580571	2531	38.341585	2231	43.829165	2559	43.551245	2511	38.418584	2168	39.725146	2242	0.988486321	-0.042251991	normal	0.986416961	-0.062709192	normal	0.974800795	-0.198959596	normal	0.641802853	-0.102489758	normal	[F]	Nucleotide transport and metabolism	"Molecular Function: phosphoribosylamine-glycine ligase activity (GO:0004637);; Molecular Function: ATP binding (GO:0005524);; Biological Process: biosynthetic process (GO:0009058);; Biological Process: purine nucleobase biosynthetic process (GO:0009113);; Molecular Function: hydroxymethyl-, formyl- and related transferase activity (GO:0016742);; "	"K11787|0|hsa:2618|GART, AIRS, GARS, GARTF, PAIS, PGFT, PRGS; phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase (EC:2.1.2.2 6.3.3.1 6.3.4.13); K11787 phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1] (A)"	Purine metabolism (ko00230);; One carbon pool by folate (ko00670)	[F]	Nucleotide transport and metabolism	"Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain;; Formyl transferase;; AIR synthase related protein, C-terminal domain;; Phosphoribosylglycinamide synthetase, N domain;; Phosphoribosylglycinamide synthetase, C domain;; AIR synthase related protein, N-terminal domain;; ATP-grasp domain;; ATP-grasp domain;; Carbamoyl-phosphate synthase L chain, ATP binding domain;; ATP-grasp domain"	Phosphoribosylglycinamide formyltransferase GN=GART OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: trifunctional purine biosynthetic protein adenosine-3 [Ailuropoda melanoleuca] 
ENSG00000159140(SON)	--	40.87361	5744	44.626967	6433	40.13232	5718	44.01512	6218	46.409977	6533	37.952994	5702	0.993420731	0.083541124	normal	0.99446705	0.0008272	normal	0.994052213	-0.012330757	normal	0.942238902	0.022768899	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	G-patch domain;; double strand RNA binding domain from DEAD END PROTEIN 1;; DExH-box splicing factor binding site	Protein SON OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: protein SON isoform X3 [Equus przewalskii]
ENSG00000159147(DONSON)	--	108.260235	1486	108.309067	1524	108.214989	1493	116.6564912	1680	119.958995	1662	107.869236	1495	0.976844533	0.146052773	normal	0.98082028	0.103532524	normal	0.984025157	-0.006353692	normal	0.727252346	0.081694237	normal	--	--	--	--	--	[S]	Function unknown	--	Protein downstream neighbor of Son GN=DONSON OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein downstream neighbor of Son [Orcinus orca]
ENSG00000159164(SV2A)	--	0	0	0	0	0	0	0.0123459	1	0.03838891	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K06258|0|ocu:100349415|SV2A; synaptic vesicle glycoprotein 2A; K06258 MFS transporter, VNT family, synaptic vesicle glycoprotein 2 (A)"	ECM-receptor interaction (ko04512)	[R]	General function prediction only	Major Facilitator Superfamily;; Sugar (and other) transporter;; Pentapeptide repeats (9 copies)	Synaptic vesicle glycoprotein 2A GN=SV2A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: synaptic vesicle glycoprotein 2A [Oryctolagus cuniculus]
ENSG00000159167(STC1)	--	11.20880993	789	16.03628109	1113	10.19511378	705	16.1734459	1131	10.4233305	730	16.66151965	1171	0.384525655	0.48787219	normal	0.042726245	-0.628848391	normal	0.004014132	0.722539263	normal	0.721029296	0.196023464	normal	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Stanniocalcin family	Stanniocalcin-1 (Precursor) GN=STC1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: stanniocalcin-1-like [Odobenus rosmarus divergens]
ENSG00000159173(TNNI1)	--	0	0	0.030397846	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: troponin complex (GO:0005861);; 	"K10371|8.40825e-118|ocu:100337828|TNNI1; troponin I type 1 (skeletal, slow); K10371 troponin I, slow skeletal muscle (A)"	--	[Z]	Cytoskeleton	Troponin	"Troponin I, slow skeletal muscle GN=TNNI1 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: troponin I, slow skeletal muscle [Oryctolagus cuniculus] "
ENSG00000159176(CSRP1)	--	136.4575043	4445	139.7403468	4566	146.3641918	4680	248.0185133	7905	208.3781473	6745	183.2027242	5923	0.000310916	0.799539886	normal	0.301611169	0.541312652	normal	0.940825066	0.331432705	normal	0.000536059	0.565507007	normal	--	--	--	K09377|5.53978e-104|ptr:457621|CSRP1; cysteine and glycine-rich protein 1; K09377 cysteine and glycine-rich protein (A)	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	Cysteine and glycine-rich protein 1 GN=CSRP1 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: cysteine and glycine-rich protein 1 isoform X1 [Orycteropus afer afer]
ENSG00000159184(HOXB13)	--	2.74852	194	2.24586	163	2.02284	147	3.23599	230	3.48701	244	3.8741	275	0.944922672	0.213192897	normal	0.468521006	0.556337794	normal	0.003715214	0.888534733	normal	0.041581811	0.55059431	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	Hox protein A13 N terminal;; Homeobox domain	Homeobox protein Hox-B13 GN=HOXB13 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein Hox-B13 [Galeopterus variegatus]
ENSG00000159197(KCNE2)	--	0.0576228	1	0	0	0	0	0	0	0.0559699	0	0.0568824	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: voltage-gated potassium channel activity (GO:0005249);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	"K04896|4.82105e-87|pon:100447172|KCNE2; potassium voltage-gated channel, Isk-related family, member 2; K04896 potassium voltage-gated channel Isk-related subfamily E member 2 (A)"	Gastric acid secretion (ko04971)	--	--	Slow voltage-gated potassium channel	Potassium voltage-gated channel subfamily E member 2 GN=KCNE2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily E member 2 [Mustela putorius furo] 
ENSG00000159199(ATP5G1)	--	245.3488263	1671	246.8498613	1717	269.554746	1889	268.8517871	1905	249.19564	1673	182.7131588	1252	0.976985359	0.158110779	normal	0.983916935	-0.05882666	normal	0.056918127	-0.601084212	normal	0.61296192	-0.149897032	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting two-sector ATPase complex, proton-transporting domain (GO:0033177);; "	"K02128|4.91696e-75|ptr:455195|ATP5G1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9); K02128 F-type H+-transporting ATPase subunit c (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	ATP synthase subunit C	"ATP synthase F(0) complex subunit C1, mitochondrial (Precursor) GN=ATP5G1 OS=Homo sapiens (Human) PE=2 SV=2"	C	Energy production and conversion	"PREDICTED: ATP synthase F(0) complex subunit C1, mitochondrial isoform X2 [Galeopterus variegatus]"
ENSG00000159200(RCAN1)	--	6.731093668	271	6.942453954	276	6.92030993	278	8.80928957	357	10.96045652	440	10.33384311	406	0.829172495	0.364991272	normal	0.080017415	0.648570451	normal	0.352198287	0.535678226	normal	0.01684809	0.523457425	normal	--	--	Biological Process: calcium-mediated signaling (GO:0019722);; 	K17901|0|pps:100987139|RCAN1; regulator of calcineurin 1; K17901 calcipressin-1 (A)	Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921)	[TR]	Signal transduction mechanisms;; General function prediction only	Calcipressin	Calcipressin-1 GN=RCAN1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: calcipressin-1 isoform X2 [Elephantulus edwardii]
ENSG00000159202(UBE2Z)	--	68.67	3761	69.99765	3847	68.721278	3782	75.29819	4188	71.868221	3986	64.89371	3647	0.989189081	0.124264752	normal	0.991632932	0.029769826	normal	0.991038188	-0.060705885	normal	0.907481597	0.031973722	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10585|0|ssc:100523993|ubiquitin-conjugating enzyme E2 Z-like; K10585 ubiquitin-conjugating enzyme E2 Z [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 Z GN=UBE2Z OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 Z [Chrysochloris asiatica]
ENSG00000159208(CIART)	--	0.432524494	9	0.333846017	8	0.150345727	3	0.238834973	3	0.189827281	4	0.435861652	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transcription regulatory region sequence-specific DNA binding (GO:0000976);; Biological Process: circadian regulation of gene expression (GO:0032922);; 	--	--	--	--	--	Circadian-associated transcriptional repressor GN=CIART OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf51 homolog [Ceratotherium simum simum]
ENSG00000159210(SNF8)	--	73.75320928	1816	72.25540737	1847	71.46660645	1853	74.97710796	1868	70.78330847	1792	69.569172	1757	0.986075592	0.009889739	normal	0.984439468	-0.064985764	normal	0.983812287	-0.084968907	normal	0.857893181	-0.047489043	normal	--	--	--	"K12188|7.4914e-177|hsa:11267|SNF8, Dot3, EAP30, VPS22; SNF8, ESCRT-II complex subunit; K12188 ESCRT-II complex subunit VPS22 (A)"	Endocytosis (ko04144)	[K]	Transcription	EAP30/Vps36 family	Vacuolar-sorting protein SNF8 GN=SNF8 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: vacuolar-sorting protein SNF8 [Oryctolagus cuniculus]
ENSG00000159212(CLIC6)	--	0.040137801	3	0	0	0	0	0.05261993	4	0.103353967	7	0.026360064	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05026|0|hsa:54102|CLIC6, CLIC1L; chloride intracellular channel 6; K05026 chloride intracellular channel protein 6 (A)"	--	[P]	Inorganic ion transport and metabolism	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Chloride intracellular channel protein 6 GN=CLIC6 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: chloride intracellular channel protein 6 [Lipotes vexillifer]
ENSG00000159214(CCDC24)	--	5.193244	122	3.920917	98	5.20244	127	3.330856	79	3.619877	86	3.087526	74	0.56540899	-0.647569258	normal	0.959909462	-0.206467695	normal	0.250218364	-0.775282604	normal	0.160031677	-0.558935431	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 24 GN=CCDC24 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 24 isoform X1 [Galeopterus variegatus] 
ENSG00000159216(RUNX1)	--	4.12121573	396	4.325209361	392	3.5136099	366	6.765273772	725	7.189856517	665	4.770651168	493	0.000451293	0.839207902	normal	0.007208584	0.738861705	normal	0.691935185	0.419952177	normal	0.003691226	0.683991732	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K08367|0|ptr:101058316|RUNX1; runt-related transcription factor 1; K08367 runt-related transcription factor 1 (A)	Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221)	[K]	Transcription	Runt domain;; Runx inhibition domain	Runt-related transcription factor 1 GN=RUNX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: runt-related transcription factor 1 [Odobenus rosmarus divergens] 
ENSG00000159217(IGF2BP1)	--	23.3419191	3698	25.5519	3891	22.813949	3590	27.197054	4215	27.1938039	4268	27.213403	4263	0.98682371	0.157893668	normal	0.9897698	0.111951084	normal	0.974371398	0.239501079	normal	0.39113356	0.167997694	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	K17391|0|pon:100451737|IGF2BP1; insulin-like growth factor 2 mRNA binding protein 1; K17391 insulin-like growth factor 2 mRNA-binding protein 1 (A)	MicroRNAs in cancer (ko05206)	[AR]	RNA processing and modification;; General function prediction only	"KH domain;; KH domain;; KH domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; KH domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; NusA-like KH domain"	Insulin-like growth factor 2 mRNA-binding protein 1 GN=IGF2BP1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: insulin-like growth factor 2 mRNA-binding protein 1 isoform X1 [Tupaia chinensis]
ENSG00000159224(GIP)	--	3.761990448	26	5.135070102	34	5.338775	36	2.221698063	16	2.03945	13	2.77412316	18	0.966276905	-0.679606793	normal	0.516649699	-1.310897512	normal	0.838790706	-0.950783307	normal	0.093410215	-1.051012139	normal	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05258|9.62516e-83|hsa:2695|GIP; gastric inhibitory polypeptide; K05258 gastric inhibitory polypeptide (A)	Insulin secretion (ko04911)	--	--	Peptide hormone	Gastric inhibitory polypeptide (Precursor) GN=GIP OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: gastric inhibitory polypeptide isoform X1 [Sus scrofa]
ENSG00000159228(CBR1)	--	87.6900026	2145	80.845988	2024	84.631263	2133	73.910279	1822	73.97051801	1792	61.020558	1497	0.948296293	-0.26607987	normal	0.971156969	-0.196908733	normal	0.265810654	-0.518659875	normal	0.042832022	-0.323879605	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K00079|0|pps:100984486|CBR1; carbonyl reductase 1; K00079 carbonyl reductase 1 [EC:1.1.1.184 1.1.1.189 1.1.1.197] (A)	Arachidonic acid metabolism (ko00590);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain	Carbonyl reductase [NADPH] 1 GN=CBR1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: carbonyl reductase [NADPH] 1 [Orycteropus afer afer]
ENSG00000159231(CBR3)	--	7.02082	128	5.76102	109	7.04338	133	7.1827	134	8.23124	150	5.04975	93	0.96840355	0.034848105	normal	0.846251176	0.434054981	normal	0.773799318	-0.517342649	normal	1	0.005244848	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00084|0|hsa:874|CBR3, HEL-S-25, SDR21C2, hCBR3; carbonyl reductase 3 (EC:1.1.1.184); K00084 carbonyl reductase 3 [EC:1.1.1.184] (A)"	Arachidonic acid metabolism (ko00590);; Metabolism of xenobiotics by cytochrome P450 (ko00980)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase	Carbonyl reductase [NADPH] 3 GN=CBR3 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: carbonyl reductase [NADPH] 3 [Tupaia chinensis] 
ENSG00000159251(ACTC1)	--	0	0	0	0	0	0	0	0	0.0275938	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	--	"K12314|0|ptg:102958158|ACTC1; actin, alpha, cardiac muscle 1; K12314 actin, alpha cardiac muscle (A)"	Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Actin	"Actin, alpha cardiac muscle 1 (Precursor) GN=ACTC1 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: actin, alpha cardiac muscle 1 [Panthera tigris altaica]"
ENSG00000159256(MORC3)	--	4.7776744	383	4.5623343	362	4.879800084	390	5.222442725	424	4.125791159	333	4.680526	376	0.963301857	0.115447339	normal	0.957842313	-0.141278481	normal	0.967791691	-0.060792805	normal	0.958499295	-0.024111292	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"CW-type Zinc Finger;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	MORC family CW-type zinc finger protein 3 GN=MORC3 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: MORC family CW-type zinc finger protein 3 [Tupaia chinensis]
ENSG00000159259(CHAF1B)	--	7.661219903	625	7.781410005	632	8.092105156	654	6.635095689	539	7.254408354	588	4.989014004	406	0.93171405	-0.243757167	normal	0.96569679	-0.125224219	normal	0.016005408	-0.694045755	normal	0.085366245	-0.339768256	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10751|0|hsa:8208|CHAF1B, CAF-1, CAF-IP60, CAF1, CAF1A, CAF1P60, MPHOSPH7, MPP7; chromatin assembly factor 1, subunit B (p60); K10751 chromatin assembly factor 1 subunit B (A)"	--	[BL]	"Chromatin structure and dynamics;; Replication, recombination and repair"	"Chromatin assembly factor complex 1 subunit p60, C-terminal;; WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Chromatin assembly factor 1 subunit B GN=CHAF1B OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: chromatin assembly factor 1 subunit B [Galeopterus variegatus]
ENSG00000159261(CLDN14)	--	0.067788498	2	0.218116921	4	0	0	0.322183617	9	0.36136558	10	0.267840448	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06087|3.57402e-131|mcf:102137709|CLDN14, Claudin-14; claudin 14; K06087 claudin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-14 GN=CLDN14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: claudin-14 [Trichechus manatus latirostris]
ENSG00000159263(SIM2)	--	9.414124	844	10.976579	920	9.527251	737	5.2600688	465	7.207979	626	6.395826	545	7.50E-05	-0.888630588	normal	0.127595558	-0.57574285	normal	0.585264801	-0.442639472	normal	0.000376778	-0.633288676	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09100|0|hsa:6493|SIM2, HMC13F06, HMC29C01, SIM, bHLHe15; single-minded family bHLH transcription factor 2; K09100 single-minded (A)"	--	[K]	Transcription	Single-minded protein C-terminus;; PAS fold;; PAS domain;; PAS fold;; Helix-loop-helix DNA-binding domain	Single-minded homolog 2 GN=SIM2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: single-minded homolog 2 [Orcinus orca]
ENSG00000159267(HLCS)	--	6.681442765	629	7.993716269	579	5.882226587	546	5.700831464	534	5.836864711	667	5.852300615	616	0.918546014	-0.26634546	normal	0.955124647	0.182253058	normal	0.958825876	0.165306663	normal	0.933925177	0.030054727	normal	[H]	Coenzyme transport and metabolism	Biological Process: cellular protein modification process (GO:0006464);; 	"K01942|0|hsa:3141|HLCS, HCS; holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) (EC:6.3.4.10 6.3.4.11 6.3.4.15 6.3.4.9); K01942 biotin--protein ligase [EC:6.3.4.9 6.3.4.10 6.3.4.11 6.3.4.15] (A)"	Biotin metabolism (ko00780)	[H]	Coenzyme transport and metabolism	"Biotin/lipoate A/B protein ligase family;; Biotin protein ligase C terminal domain;; Biotin-protein ligase, N terminal"	Biotin--[acetyl-CoA-carboxylase] ligase GN=HLCS OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: biotin--protein ligase [Equus przewalskii] 
ENSG00000159289(GOLGA6A)	--	0.0518141	4	0	0	0	0	0.0386253	3	0	0	0.0128408	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 6A GN=GOLGA6A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X2 [Galeopterus variegatus]
ENSG00000159307(SCUBE1)	--	0.048642897	1	0.046695181	2	0.233357112	4	0	0	0.045446414	3	0.00438131	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; GCC2 and GCC3;; Calcium-binding EGF domain;; EGF-like domain;; EGF domain;; CUB domain	"Signal peptide, CUB and EGF-like domain-containing protein 1 (Precursor) GN=SCUBE1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: signal peptide, CUB and EGF-like domain-containing protein 1 [Galeopterus variegatus]"
ENSG00000159314(ARHGAP27)	--	7.297010551	540	7.5193161	565	8.45846956	588	6.422637068	470	5.948195	392	7.312391913	494	0.93656931	-0.230427434	normal	0.255180116	-0.547055349	normal	0.922905721	-0.258869205	normal	0.09739485	-0.341242941	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; WW domain;; PH domain;; Pleckstrin homology domain	Rho GTPase-activating protein 27 GN=ARHGAP27 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 27 [Orcinus orca]
ENSG00000159322(ADPGK)	--	47.068578	2040	42.1684797	1805	43.20666354	1956	46.833672	2101	44.4200846	1886	43.0353872	1885	0.987157985	0.011666089	normal	0.985284496	0.041869962	normal	0.985478043	-0.061584782	normal	0.993303525	-0.003942151	normal	--	--	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08074|0|hsa:83440|ADPGK, 2610017G09Rik, ADP-GK; ADP-dependent glucokinase (EC:2.7.1.147); K08074 ADP-dependent glucokinase [EC:2.7.1.147] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Carbon metabolism (ko01200)	[GR]	Carbohydrate transport and metabolism;; General function prediction only	ADP-specific Phosphofructokinase/Glucokinase conserved region	ADP-dependent glucokinase (Precursor) GN=ADPGK OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: ADP-dependent glucokinase isoform X2 [Equus przewalskii]
ENSG00000159335(PTMS)	--	370.4593202	6901	450.7153941	7638	404.7990696	7356	334.240726	6803	354.4384082	7057	350.5490449	7012	0.994622187	-0.051455069	normal	0.992730908	-0.135538539	normal	0.994413116	-0.077370632	normal	0.71373972	-0.090114674	normal	--	--	--	--	--	--	--	Prothymosin/parathymosin family	--	--	--	--
ENSG00000159337(PLA2G4D)	--	0	0	0.0714834	5	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipase activity (GO:0004620);; Biological Process: phospholipid catabolic process (GO:0009395);; 	"K16342|0|hsa:283748|PLA2G4D, cPLA2delta; phospholipase A2, group IVD (cytosolic) (EC:3.1.1.4); K16342 cytosolic phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Platelet activation (ko04611);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Oxytocin signaling pathway (ko04921);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Lysophospholipase catalytic domain;; C2 domain	Cytosolic phospholipase A2 delta GN=PLA2G4D OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: cytosolic phospholipase A2 delta [Galeopterus variegatus]
ENSG00000159339(PADI4)	--	0.0209194	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein-arginine deiminase activity (GO:0004668);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein citrullination (GO:0018101);; 	"K01481|0|hsa:23569|PADI4, PAD, PAD4, PADI5, PDI4, PDI5; peptidyl arginine deiminase, type IV (EC:3.5.3.15); K01481 protein-arginine deiminase [EC:3.5.3.15] (A)"	--	--	--	Protein-arginine deiminase (PAD);; Protein-arginine deiminase (PAD) middle domain;; Protein-arginine deiminase (PAD) N-terminal domain	Protein-arginine deiminase type-4 GN=PADI4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein-arginine deiminase type-4 [Galeopterus variegatus]
ENSG00000159346(ADIPOR1)	--	57.0735032	2074	50.37128043	1873	50.98883396	1896	47.01571759	1734	41.39366264	1507	53.61691355	1977	0.933064448	-0.288909803	normal	0.886063167	-0.334796009	normal	0.985861553	0.052021828	normal	0.32539467	-0.184119338	normal	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; 	K07297|0|ptr:457635|ADIPOR1; adiponectin receptor 1; K07297 adiponectin receptor (A)	AMPK signaling pathway (ko04152);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Adiponectin receptor protein 1 GN=ADIPOR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	adiponectin receptor protein 1 [Felis catus] 
ENSG00000159348(CYB5R1)	--	20.837388	427	19.09532304	406	15.201	360	23.708689	556	26.92044132	579	22.02408009	498	0.832678454	0.348913674	normal	0.4567383	0.489124148	normal	0.575201687	0.458213934	normal	0.030789758	0.431224962	normal	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00326|0|ptr:740001|NADH-cytochrome b5 reductase 1; K00326 cytochrome-b5 reductase [EC:1.6.2.2] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Oxidoreductase NAD-binding domain;; Oxidoreductase FAD-binding domain;; Ferric reductase NAD binding domain	NADH-cytochrome b5 reductase 1 GN=CYB5R1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADH-cytochrome b5 reductase 1 [Galeopterus variegatus]
ENSG00000159352(PSMD4)	--	94.74962271	2357	91.73260383	2360	93.45006296	2385	104.1276778	2663	101.0820343	2490	93.21360704	2326	0.983015228	0.145179338	normal	0.987514844	0.055897452	normal	0.987859047	-0.044401102	normal	0.834721539	0.053041222	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K03029|0|mcf:102138179|PSMD4; proteasome (prosome, macropain) 26S subunit, non-ATPase, 4; K03029 26S proteasome regulatory subunit N10 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	von Willebrand factor type A domain;; Ubiquitin interaction motif;; Ssl1-like	26S proteasome non-ATPase regulatory subunit 4 GN=PSMD4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 4 isoform 1 [Dasypus novemcinctus]
ENSG00000159363(ATP13A2)	--	14.50894533	892	12.68221506	881	14.13692502	994	21.6886051	1501	24.13033022	1666	22.23166183	1468	0.003607088	0.719011491	normal	2.72E-05	0.896610636	normal	0.148348393	0.553545516	normal	3.66E-07	0.723266432	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; 	"K13526|0|hsa:23400|ATP13A2, CLN12, HSA9947, KRPPD, PARK9; ATPase type 13A2 (EC:3.6.3.8); K13526 cation-transporting ATPase 13A2 [EC:3.6.3.-] (A)"	--	[P]	Inorganic ion transport and metabolism	E1-E2 ATPase;; P5-type ATPase cation transporter;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase	Probable cation-transporting ATPase 13A2 GN=ATP13A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: probable cation-transporting ATPase 13A2 [Galeopterus variegatus]
ENSG00000159377(PSMB4)	--	236.145	2921	234.783	3011	226.356	2904	242.348	3119	241.985	2981	237.924	3006	0.989448509	0.063756476	normal	0.989678607	-0.035854792	normal	0.989764373	0.041490876	normal	0.942238902	0.022068266	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02736|0|pps:100990503|PSMB4; proteasome (prosome, macropain) subunit, beta type, 4; K02736 20S proteasome subunit beta 7 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-4 (Precursor) GN=PSMB4 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-4 [Galeopterus variegatus]
ENSG00000159387(IRX6)	--	0	0	0.0167024	1	0.0162263	0	0	0	0	0	0.0167875	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	Homeobox KN domain;; Homeobox domain	Iroquois-class homeodomain protein IRX-6 GN=IRX6 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: iroquois-class homeodomain protein IRX-6 [Tupaia chinensis]
ENSG00000159388(BTG2)	--	8.07151	363	10.7665	489	8.95053	403	9.27646	418	14.4236	643	14.9788	675	0.95343096	0.172022236	normal	0.792999264	0.372550194	normal	0.006523116	0.733665934	normal	0.24334465	0.448172728	normal	--	--	--	"K14443|7.7817e-101|ptr:740912|BTG2; BTG family, member 2; K14443 protein Tob/BTG (A)"	RNA degradation (ko03018)	[TR]	Signal transduction mechanisms;; General function prediction only	BTG family	Protein BTG2 GN=BTG2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein BTG2 [Galeopterus variegatus]
ENSG00000159399(HK2)	--	1.237132901	140	1.164642352	134	0.941691791	107	1.847027079	210	0.853221227	95	0.920773751	104	0.547357914	0.549179595	normal	0.776790966	-0.510778264	normal	0.969783869	-0.048621643	normal	0.939158258	0.078108131	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: ATP binding (GO:0005524);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K00844|0|hsa:3099|HK2, HKII, HXK2; hexokinase 2 (EC:2.7.1.1); K00844 hexokinase [EC:2.7.1.1] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520);; Butirosin and neomycin biosynthesis (ko00524);; Carbon metabolism (ko01200);; HIF-1 signaling pathway (ko04066);; Insulin signaling pathway (ko04910);; Type II diabetes mellitus (ko04930);; Carbohydrate digestion and absorption (ko04973);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Hexokinase;; Hexokinase	Hexokinase-2 GN=HK2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: hexokinase-2 [Oryctolagus cuniculus]
ENSG00000159403(C1R)	--	5.232894423	291	5.402953393	306	4.335422477	242	36.31017248	1942	48.06051955	2576	59.71792119	3076	0	2.701256631	up	0	3.045895744	up	0	3.651434476	up	6.09E-15	3.157941299	up	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: proteolysis (GO:0006508);; 	"K01330|0|hsa:715|C1R; complement component 1, r subcomponent (EC:3.4.21.41); K01330 complement component 1, r subcomponent [EC:3.4.21.41] (A)"	Phagosome (ko04145);; Complement and coagulation cascades (ko04610);; Pertussis (ko05133);; Staphylococcus aureus infection (ko05150);; Systemic lupus erythematosus (ko05322)	[E]	Amino acid transport and metabolism	Trypsin;; CUB domain;; Sushi domain (SCR repeat);; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain;; Complement Clr-like EGF-like	Complement C1r subcomponent light chain (Precursor) GN=C1R OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: complement C1r subcomponent isoform 1 [Ceratotherium simum simum]
ENSG00000159409(CELF3)	--	0.022164469	1	0.067069328	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13207|0|lve:103088027|CELF3; CUGBP, Elav-like family member 3; K13207 CUG-BP- and ETR3-like factor (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	CUGBP Elav-like family member 3 GN=CELF3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: CUGBP Elav-like family member 3 isoform X2 [Bos taurus]
ENSG00000159423(ALDH4A1)	--	9.195755003	534	7.5007	459	8.62408812	523	10.39775668	576	11.74986873	649	10.22143069	610	0.970025221	0.0781802	normal	0.486625526	0.476970183	normal	0.944946949	0.21313568	normal	0.238320253	0.254666139	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00294|0|pps:100984082|ALDH4A1; aldehyde dehydrogenase 4 family, member A1; K00294 1-pyrroline-5-carboxylate dehydrogenase [EC:1.2.1.88] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330)"	[E]	Amino acid transport and metabolism	Aldehyde dehydrogenase family	"Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (Precursor) GN=ALDH4A1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial [Leptonychotes weddellii]"
ENSG00000159433(STARD9)	--	0.800916727	294	0.977138817	319	0.744328475	277	0.67908662	247	0.875335221	310	0.699197306	247	0.913980604	-0.280535417	normal	0.965411455	-0.062414597	normal	0.952755555	-0.172667494	normal	0.604034271	-0.167873041	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; Molecular Function: lipid binding (GO:0008289);; 	K16491|0|hsa:57519|STARD9; StAR-related lipid transfer (START) domain containing 9; K16491 StAR-related lipid transfer protein 9 (A)	--	--	--	Kinesin motor domain;; START domain;; FHA domain	StAR-related lipid transfer protein 9 GN=STARD9 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: stAR-related lipid transfer protein 9 [Ceratotherium simum simum]
ENSG00000159445(THEM4)	--	9.16747963	402	7.404948687	291	7.540858601	307	9.593056031	499	11.22737183	564	6.604025075	347	0.907844276	0.280049872	normal	0.000118553	0.929718615	normal	0.953801615	0.16762844	normal	0.205121037	0.473529319	normal	--	--	--	"K16339|3.45281e-179|hsa:117145|THEM4, CTMP; thioesterase superfamily member 4 (EC:3.1.2.2); K16339 thioesterase superfamily member 4 (A)"	PI3K-Akt signaling pathway (ko04151)	[S]	Function unknown	Thioesterase superfamily	Acyl-coenzyme A thioesterase THEM4 (Precursor) GN=THEM4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: acyl-coenzyme A thioesterase THEM4 [Tupaia chinensis]
ENSG00000159450(TCHH)	--	0.092178598	17	0.035979166	7	0.025083734	4	0.233858549	44	0.178022594	33	0.256857908	48	0.335582391	1.267621615	normal	0.039256579	2.000438317	normal	8.10E-07	3.160036304	up	0.000123664	2.136074355	up	--	--	--	"K18626|4.51736e-69|hsa:7062|TCHH, THH, THL, TRHY; trichohyalin; K18626 trichohyalin (A)"	--	--	--	S-100/ICaBP type calcium binding domain	Trichohyalin GN=TCHH OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: trichohyalin [Galeopterus variegatus]
ENSG00000159459(UBR1)	--	5.214932239	656	4.689918507	643	5.228656832	704	4.639792619	639	4.641306	625	4.507143472	616	0.972450659	-0.068549463	normal	0.971994975	-0.06224062	normal	0.951302282	-0.200475768	normal	0.664425654	-0.112578286	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein catabolic process (GO:0030163);; 	"K10625|0|hsa:197131|UBR1, JBS; ubiquitin protein ligase E3 component n-recognin 1; K10625 E3 ubiquitin-protein ligase UBR1 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATP-dependent Clp protease adaptor protein ClpS;; Putative zinc finger in N-recognin (UBR box)	E3 ubiquitin-protein ligase UBR1 GN=UBR1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase UBR1 [Odobenus rosmarus divergens]
ENSG00000159461(AMFR)	--	45.97238122	2859	43.85911787	2769	44.64688304	2589	52.14363019	3247	54.76453021	3355	54.21307732	3372	0.98455331	0.152687471	normal	0.964830174	0.255394275	normal	0.856191283	0.372726826	normal	0.129983792	0.258357447	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: metal ion binding (GO:0046872);; 	"K10636|0|hsa:267|AMFR, GP78, RNF45; autocrine motility factor receptor, E3 ubiquitin protein ligase (EC:6.3.2.19); K10636 autocrine motility factor receptor [EC:6.3.2.19] (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; CUE domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; RING-H2 zinc finger;; Anaphase-promoting complex subunit 11 RING-H2 finger"	E3 ubiquitin-protein ligase AMFR GN=AMFR OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase AMFR [Odobenus rosmarus divergens]
ENSG00000159479(MED8)	--	13.4143293	464	11.870621	423	15.04224	537	16.33464	575	14.333536	490	13.52734	484	0.909736294	0.277777371	normal	0.94938324	0.190065738	normal	0.958915624	-0.157738342	normal	0.731740104	0.09999742	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15129|0|ggo:101154489|MED8; mediator of RNA polymerase II transcription subunit 8; K15129 mediator of RNA polymerase II transcription subunit 8 (A)	Herpes simplex infection (ko05168)	[S]	Function unknown	Mediator of RNA polymerase II transcription complex subunit 8	Mediator of RNA polymerase II transcription subunit 8 GN=MED8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 8 isoformX1 [Equus caballus]
ENSG00000159496(RGL4)	--	0.72512071	43	0.941160198	55	0.509167	27	0.727730047	42	0.543051726	32	0.753644249	50	0.980841951	-0.062519169	normal	0.79029173	-0.774530856	normal	0.778569359	0.845382959	normal	0.985354717	-0.0333548	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[T]	Signal transduction mechanisms	RasGEF domain	Ral-GDS-related protein GN=RGL4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: ral-GDS-related protein-like [Oryctolagus cuniculus]
ENSG00000159556(ISL2)	--	3.619504612	136	3.344364108	115	3.373650596	125	2.596915328	94	3.37848421	127	3.084996046	114	0.701385404	-0.556102839	normal	0.963771471	0.120262757	normal	0.963806343	-0.139418797	normal	0.705643346	-0.187078484	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K18492|0|ptr:738258|ISL2; ISL LIM homeobox 2; K18492 insulin gene enhancer protein ISL-2 (A)	--	[R]	General function prediction only	LIM domain;; Homeobox domain	Insulin gene enhancer protein ISL-2 GN=ISL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: insulin gene enhancer protein ISL-2 [Dasypus novemcinctus]
ENSG00000159579(RSPRY1)	--	13.63806646	820	14.63295609	775	15.13168243	871	18.97751739	1154	17.31649143	1044	15.50215353	939	0.495343778	0.461383327	normal	0.706584917	0.40773916	normal	0.974303821	0.099993753	normal	0.059296814	0.325570105	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[A]	RNA processing and modification	"SPRY domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger and SPRY domain-containing protein 1 (Precursor) GN=RSPRY1 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger and SPRY domain-containing protein 1 [Ochotona princeps]
ENSG00000159588(CCDC17)	--	0.024997647	1	0.122386747	5	0.023848845	0	0.099071241	4	0	0	0.142329089	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 17 GN=CCDC17 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 17 isoform 1 [Ceratotherium simum simum]
ENSG00000159592(GPBP1L1)	--	17.321981	1131	17.83182	1163	17.798913	1147	15.561489	1019	15.889819	1033	19.4658	1271	0.964547751	-0.181017908	normal	0.962062632	-0.192172065	normal	0.973868598	0.139632239	normal	0.777970337	-0.070887343	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	--	--	--	--	Vascular protein family Vasculin-like 1	Vasculin-like protein 1 GN=GPBP1L1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: vasculin-like protein 1 [Condylura cristata]
ENSG00000159593(NAE1)	--	45.29528296	1385	45.22463082	1338	48.38114596	1454	51.9603234	1585	49.07061855	1485	39.21415373	1175	0.973329173	0.163594868	normal	0.976968979	0.128820009	normal	0.895506566	-0.315292436	normal	0.998695285	0.00139016	normal	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	K04532|0|ggo:101138325|NAE1; NEDD8-activating enzyme E1 regulatory subunit isoform 1; K04532 amyloid beta precursor protein binding protein 1 (A)	Alzheimer's disease (ko05010)	[O]	"Posttranslational modification, protein turnover, chaperones"	ThiF family	NEDD8-activating enzyme E1 regulatory subunit GN=NAE1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NEDD8-activating enzyme E1 regulatory subunit isoform X2 [Vicugna pacos]
ENSG00000159596(TMEM69)	--	18.08792	398	17.08458	368	14.85961	329	15.37948	335	16.71932	364	17.14462	394	0.910240614	-0.278266937	normal	0.967569382	-0.037040821	normal	0.926423877	0.250761986	normal	0.95908328	-0.023575487	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3429)	Transmembrane protein 69 GN=TMEM69 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 69 [Ursus maritimus]
ENSG00000159618(ADGRG5)	--	0	0	0	0	0	0	0.015716991	1	0.015263827	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08459|0|hsa:221188|GPR114, PGR27, ADGRG5; G protein-coupled receptor 114; K08459 G protein-coupled receptor 114 (A)"	--	--	--	7 transmembrane receptor (Secretin family);; Latrophilin/CL-1-like GPS domain	Probable G-protein coupled receptor 114 (Precursor) GN=GPR114 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 114 [Galeopterus variegatus]
ENSG00000159625(DRC7)	--	0.07430574	5	0	0	0.100251227	4	0.159268605	4	0.144534333	1	0.221567864	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein lobo homolog GN=CCDC135 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein lobo homolog [Bison bison bison]
ENSG00000159640(ACE)	--	0.337885433	22	0.14559856	8	0.129429293	13	0.048096643	5	0.069768852	6	0.03045248	3	0.436084999	-1.874519262	normal	--	--	--	--	--	--	--	--	--	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: peptidyl-dipeptidase activity (GO:0008241);; Cellular Component: membrane (GO:0016020);; 	"K01283|0|hsa:1636|ACE, ACE1, CD143, DCP, DCP1, ICH, MVCD3; angiotensin I converting enzyme (EC:3.4.15.1); K01283 peptidyl-dipeptidase A [EC:3.4.15.1] (A)"	Renin-angiotensin system (ko04614);; Chagas disease (American trypanosomiasis) (ko05142);; Hypertrophic cardiomyopathy (HCM) (ko05410)	[E]	Amino acid transport and metabolism	Angiotensin-converting enzyme	"Angiotensin-converting enzyme, soluble form (Precursor) GN=ACE OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	angiotensin-converting enzyme isoform 1 precursor [Oryctolagus cuniculus] 
ENSG00000159648(TEPP)	--	0.0772491	1	0	0	0	0	0	0	0	0	0.0759059	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Testis, prostate and placenta-expressed protein (Precursor) GN=TEPP OS=Homo sapiens (Human) PE=2 SV=3"	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: testis, prostate and placenta-expressed protein [Ceratotherium simum simum]"
ENSG00000159658(EFCAB14)	--	20.5647	2050	22.72141	2251	21.09501	2063	22.02353	2198	22.2308	2205	21.6682	2166	0.986153337	0.069684771	normal	0.986873804	-0.051179217	normal	0.986399227	0.061953654	normal	0.934578096	0.024422233	normal	--	--	--	--	--	--	--	--	EF-hand calcium-binding domain-containing protein 14 GN=EFCAB14 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: EF-hand calcium-binding domain-containing protein 14 isoform X1 [Galeopterus variegatus]
ENSG00000159674(SPON2)	--	0.246654933	7	0.353482819	11	1.09535648	6	0.210002447	4	0.385126583	11	1.484291947	44	--	--	--	--	--	--	8.84E-05	2.591612856	up	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Spondin_N	Spondin-2 (Precursor) GN=SPON2 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: spondin-2-like [Vicugna pacos]
ENSG00000159685(CHCHD6)	--	15.4252134	276	13.57682081	253	17.17203752	334	15.38262309	275	13.6489488	241	12.87531604	229	0.966904176	-0.035868875	normal	0.962551071	-0.090973557	normal	0.361837568	-0.549767503	normal	0.440026845	-0.233443639	normal	--	--	--	"K17564|5.38771e-132|hsa:84303|CHCHD6, CHCM1, PPP1R23; coiled-coil-helix-coiled-coil-helix domain containing 6; K17564 coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial (A)"	--	[K]	Transcription	Protein of unknown function (DUF737)	MICOS complex subunit MIC25 GN=CHCHD6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: coiled-coil-helix-coiled-coil-helix domain-containing protein 6, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000159692(CTBP1)	--	70.08643001	2483	50.9078261	2477	52.68275771	2537	54.57347553	2425	60.85889013	2658	64.250955	2898	0.987676637	-0.064891145	normal	0.987218982	0.080273362	normal	0.979362105	0.183540199	normal	0.777303073	0.069655384	normal	[HE]	Coenzyme transport and metabolism;; Amino acid transport and metabolism	"Molecular Function: phosphogluconate dehydrogenase (decarboxylating) activity (GO:0004616);; Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	K04496|0|cjc:100412920|CTBP1; C-terminal binding protein 1; K04496 C-terminal binding protein (A)	Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; Pathways in cancer (ko05200);; Chronic myeloid leukemia (ko05220)	[K]	Transcription	"D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain;; NAD binding domain of 6-phosphogluconate dehydrogenase"	C-terminal-binding protein 1 GN=CTBP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: C-terminal-binding protein 1 isoform X2 [Ornithorhynchus anatinus]
ENSG00000159708(LRRC36)	--	0.065041675	2	0.104906953	3	0.819934762	7	0.131209128	6	0.148137514	5	0.10424886	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K16594|0|pps:100985069|LRRC36; leucine rich repeat containing 36; K16594 leucine-rich repeat-containing protein 36 (A)	--	--	--	Leucine Rich repeats (2 copies);; Leucine rich repeat	Leucine-rich repeat-containing protein 36 GN=LRRC36 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 36 [Pteropus alecto]
ENSG00000159713(TPPP3)	--	2.463833279	50	0.953575041	23	2.182705205	45	1.087323778	22	1.542096484	31	0.796861572	16	0.329689944	-1.160062045	normal	0.976962713	0.387212669	normal	0.136128808	-1.417042975	normal	0.219089649	-0.795309776	normal	--	--	--	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	p25-alpha	Tubulin polymerization-promoting protein family member 3 GN=TPPP3 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin polymerization-promoting protein family member 3 isoform X1 [Equus caballus] 
ENSG00000159714(ZDHHC1)	--	8.776713	267	6.588938096	213	5.79246163	191	6.568165339	228	8.258597	271	8.742181	291	0.927588809	-0.257035503	normal	0.887706032	0.32396941	normal	0.275195786	0.595309253	normal	0.512874376	0.214766515	normal	--	--	--	"K18932|0|hsa:29800|ZDHHC1, C16orf1, HSU90653, ZNF377; zinc finger, DHHC-type containing 1 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC1 GN=ZDHHC1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: probable palmitoyltransferase ZDHHC1 [Equus caballus]
ENSG00000159720(ATP6V0D1)	--	53.26218174	1441	51.58213706	1428	52.28101501	1481	65.061395	1832	63.61940562	1711	69.00849677	1952	0.904091774	0.315218241	normal	0.954710465	0.239185555	normal	0.776800079	0.389742264	normal	0.050510626	0.316129776	normal	[C]	Energy production and conversion	--	"K02146|0|ocu:100350157|ATP6V0D1; ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; K02146 V-type H+-transporting ATPase subunit d (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Tuberculosis (ko05152);; Viral carcinogenesis (ko05203);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase (C/AC39) subunit	V-type proton ATPase subunit d 1 GN=ATP6V0D1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit d 1 [Oryctolagus cuniculus]
ENSG00000159723(AGRP)	--	0	0	0	0	0	0	0.193791	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: hormone-mediated signaling pathway (GO:0009755);; 	K05231|2.75536e-56|nle:100584369|AGRP; agouti related protein homolog (mouse); K05231 agouti related protein (A)	Adipocytokine signaling pathway (ko04920)	--	--	Agouti protein	Agouti-related protein (Precursor) GN=AGRP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: agouti-related protein [Odobenus rosmarus divergens]
ENSG00000159733(ZFYVE28)	--	1.733888696	129	0.938148812	63	1.359025637	81	1.206631386	85	0.935810825	68	0.567318402	39	0.588077606	-0.623449821	normal	0.973182312	0.086751695	normal	0.129138415	-1.034310119	normal	0.476215354	-0.531273071	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	FYVE zinc finger	Lateral signaling target protein 2 homolog GN=ZFYVE28 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: lateral signaling target protein 2 homolog [Oryctolagus cuniculus]
ENSG00000159753(CARMIL2)	--	0.41102	36	0.2619764	24	0.294887702	25	0.155603221	13	0.309980667	27	0.116920876	11	0.355924246	-1.397188056	normal	0.984910221	0.140168243	normal	0.894213537	-1.090869484	normal	0.276794376	-0.758297395	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[N]	Cell motility	Leucine Rich repeat;; Leucine Rich repeats (2 copies)	Leucine-rich repeat-containing protein 16C GN=RLTPR OS=Homo sapiens (Human) PE=1 SV=2	N	Cell motility	PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 16C [Pteropus alecto]
ENSG00000159761(C16orf86)	--	0.303444144	7	0.0825296	2	0.161028	3	0.295812	4	0.343811	4	0.0852991	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C16orf86 GN=C16orf86 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C16orf86 homolog [Ceratotherium simum simum]
ENSG00000159763(PIP)	--	0	0	0	0	0	0	1.87445	10	3.03057	15	3.59571	19	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Seminal vesicle autoantigen (SVA)	Prolactin-inducible protein (Precursor) GN=PIP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: prolactin-inducible protein homolog [Equus caballus] 
ENSG00000159784(FAM131B)	--	0.35063152	30	0.012960023	1	0.179787571	14	0.243450729	21	0.583014432	49	0.149769922	13	0.972481269	-0.513789847	normal	1.88E-09	4.314916866	up	--	--	--	0.623727906	0.861920697	normal	--	--	--	--	--	--	--	Putative cell signalling	Protein FAM131B GN=FAM131B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM131B [Camelus dromedarius]
ENSG00000159788(RGS12)	--	4.109397185	398	3.803587506	415	5.317035342	459	4.576530955	404	4.2712085	404	3.759817218	317	0.969676657	-0.009210113	normal	0.967487326	-0.059961134	normal	0.304934719	-0.540148764	normal	0.458762106	-0.198796343	normal	--	--	Molecular Function: receptor signaling protein activity (GO:0005057);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Molecular Function: GTPase regulator activity (GO:0030695);; 	K16449|0|pps:100994163|RGS12; regulator of G-protein signaling 12; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Raf-like Ras-binding domain;; Regulator of G protein signaling domain;; PDZ domain (Also known as DHR or GLGF);; GoLoco motif;; Phosphotyrosine interaction domain (PTB/PID)	Regulator of G-protein signaling 12 GN=RGS12 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 12 isoform X2 [Tupaia chinensis]
ENSG00000159792(PSKH1)	--	11.684821	752	12.267583	807	11.53309233	764	13.080566	857	13.817628	895	14.060894	933	0.964761132	0.157428838	normal	0.969885867	0.127665209	normal	0.915825568	0.279511555	normal	0.366689097	0.187957075	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08808|0|ptr:468116|PSKH1; protein serine kinase H1; K08808 protein serine kinase H [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Phosphotransferase enzyme family	Serine/threonine-protein kinase H1 GN=PSKH1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase H1 [Oryctolagus cuniculus]
ENSG00000159840(ZYX)	--	66.8258266	2951	65.97178612	2865	68.28240419	3112	93.35445186	3984	78.922862	3494	63.0889658	2847	0.804080302	0.40200075	normal	0.962338519	0.264791172	normal	0.985684532	-0.136621571	normal	0.410104153	0.187678599	normal	--	--	--	"K06273|0|hsa:7791|ZYX, ESP-2, HED-2; zyxin; K06273 zyxin (A)"	Focal adhesion (ko04510)	[T]	Signal transduction mechanisms	LIM domain	Zyxin GN=ZYX OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: zyxin [Galeopterus variegatus]
ENSG00000159842(ABR)	--	41.34887994	4462	35.66955281	4039	38.88466209	4420	48.04136687	5244	47.35099999	5176	36.74171208	4011	0.984355275	0.202080671	normal	0.933354737	0.336301433	normal	0.988154305	-0.14832255	normal	0.521725191	0.137633388	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: signal transduction (GO:0007165);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; RhoGEF domain;; PH domain;; C2 domain	Active breakpoint cluster region-related protein GN=ABR OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: active breakpoint cluster region-related protein isoform 1 [Odobenus rosmarus divergens]
ENSG00000159871(LYPD5)	--	0.15754258	6	0.078367304	3	0.362132407	14	0	0	0.18259022	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	u-PAR/Ly-6 domain	Ly6/PLAUR domain-containing protein 5 (Precursor) GN=LYPD5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ly6/PLAUR domain-containing protein 5 [Galeopterus variegatus]
ENSG00000159873(CCDC117)	--	10.32819845	527	11.03373472	595	10.31930004	558	9.792055002	586	10.16069089	602	7.920929281	472	0.965589052	0.121928244	normal	0.973008123	-0.004541264	normal	0.928041174	-0.249034947	normal	0.909104305	-0.039061595	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 117 GN=CCDC117 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	TPA: coiled-coil domain containing 117 [Bos taurus]
ENSG00000159882(ZNF230)	--	1.907041	127	1.76713891	119	3.4336993	130	1.615241	110	2.119329	143	1.73320914	118	0.951574574	-0.23509786	normal	0.945983766	0.2408319	normal	0.962730868	-0.146229955	normal	0.955958996	-0.040070352	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7773|ZNF230, FDZF2; zinc finger protein 230; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 230 GN=ZNF230 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein-like [Galeopterus variegatus]
ENSG00000159884(CCDC107)	--	9.465741	180	8.038986	169	9.034695	172	7.1557779	143	6.7714292	139	7.9602876	168	0.887603565	-0.359363744	normal	0.921859939	-0.300395648	normal	0.966739391	-0.041866302	normal	0.558343771	-0.232100972	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 107 (Precursor) GN=CCDC107 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 107-like [Galeopterus variegatus]
ENSG00000159885(ZNF222)	--	6.279760914	87	4.320773373	88	2.477909771	64	2.328503736	59	3.343256272	65	3.323773	77	0.822431451	-0.578640732	normal	0.905063213	-0.449466822	normal	0.962702001	0.253037044	normal	0.635096483	-0.270731739	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7673|ZNF222; zinc finger protein 222; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 222 GN=ZNF222 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 234 isoform 2 [Ceratotherium simum simum]
ENSG00000159899(NPR2)	--	2.020260051	76	1.68973	114	1.97195401	114	1.441069088	90	1.572614804	104	1.387431002	85	0.96379395	0.209203554	normal	0.962524652	-0.151768058	normal	0.891208969	-0.425234057	normal	0.804731887	-0.144809879	normal	[T]	Signal transduction mechanisms	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	K12324|0|mcf:102136908|NPR2; natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B); K12324 atrial natriuretic peptide receptor B [EC:4.6.1.2] (A)	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein tyrosine kinase;; Protein kinase domain;; Periplasmic binding protein	Atrial natriuretic peptide receptor 2 (Precursor) GN=NPR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: atrial natriuretic peptide receptor 2 isoform X2 [Ailuropoda melanoleuca] 
ENSG00000159905(ZNF221)	--	5.393002832	577	4.533378945	470	4.074556624	535	3.728187622	420	4.110331442	405	4.268631474	446	0.442730271	-0.487485579	normal	0.933099961	-0.235348749	normal	0.915296059	-0.269949663	normal	0.112872655	-0.336733907	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7638|ZNF221; zinc finger protein 221; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger"	Zinc finger protein 221 GN=ZNF221 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein-like [Galeopterus variegatus]
ENSG00000159915(ZNF233)	--	1.501376	51	2.136501	71	1.201514	54	1.97681531	51	0.788556	33	1.5997987	58	0.978821472	-0.029930579	normal	0.13760793	-1.091849082	normal	0.976401126	0.092307273	normal	0.599269878	-0.330928337	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:353355|ZNF233; zinc finger protein 233; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; BolA-like protein"	Zinc finger protein 233 GN=ZNF233 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 233 [Dasypus novemcinctus]
ENSG00000159917(ZNF235)	--	3.84282005	134	4.60906	159	5.219432	165	3.850628	128	4.669260023	146	5.83827	167	0.966068578	-0.095797423	normal	0.959303544	-0.143064401	normal	0.967384826	0.009008565	normal	0.890790288	-0.07476566	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:9310|ZNF235, ANF270, HZF6, ZFP93, ZNF270; zinc finger protein 235; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein 235 GN=ZNF235 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 235 isoform 1 [Ceratotherium simum simum]
ENSG00000159921(GNE)	--	13.70662205	1173	14.57962016	1228	15.07903692	1270	14.85314361	1251	14.20078606	1162	17.94887117	1494	0.980386611	0.061967912	normal	0.977378469	-0.100999162	normal	0.956639917	0.225812041	normal	0.785695034	0.069285383	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K12409|0|hsa:10020|GNE, DMRV, GLCNE, IBM2, NM, Uae1; glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (EC:2.7.1.60 3.2.1.183); K12409 bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:3.2.1.183 2.7.1.60] (A)"	Amino sugar and nucleotide sugar metabolism (ko00520)	--	--	UDP-N-acetylglucosamine 2-epimerase;; ROK family	N-acetylmannosamine kinase GN=GNE OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase [Tupaia chinensis]
ENSG00000159958(TNFRSF13C)	--	0.533498657	37	0.483204784	28	0.556398846	30	0.24597393	12	0.211201396	14	0.199535909	14	0.180176589	-1.537840972	normal	0.906712055	-0.947737632	normal	0.862805684	-1.030191352	normal	0.038558892	-1.268698142	normal	--	--	--	"K05151|1.50541e-71|hsa:115650|TNFRSF13C, BAFF-R, BAFFR, BROMIX, CD268, CVID4, prolixin; tumor necrosis factor receptor superfamily, member 13C; K05151 tumor necrosis factor receptor superfamily member 13C (A)"	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Intestinal immune network for IgA production (ko04672);; HTLV-I infection (ko05166);; Primary immunodeficiency (ko05340)	--	--	"BAFF-R, TALL-1 binding"	Tumor necrosis factor receptor superfamily member 13C GN=TNFRSF13C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 13C [Ceratotherium simum simum]
ENSG00000160007(ARHGAP35)	--	30.89363945	6045	30.11598135	5912	31.53021761	6205	25.1963849	4937	27.59753073	5369	27.28871829	5346	0.948416867	-0.322848971	normal	0.989619308	-0.160376353	normal	0.983467768	-0.223204149	normal	0.197313555	-0.235427858	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: signal transduction (GO:0007165);; 	K05732|0|pps:100975102|ARHGAP35; Rho GTPase activating protein 35; K05732 glucocorticoid receptor DNA-binding factor 1 (A)	Focal adhesion (ko04510);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	RhoGAP domain;; Ras family;; FF domain	Rho GTPase-activating protein 35 GN=ARHGAP35 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: rho GTPase-activating protein 35 [Leptonychotes weddellii]
ENSG00000160013(PTGIR)	--	0	0	0.0575119	2	0.055979645	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04263|0|hsa:5739|PTGIR, IP, PRIPR; prostaglandin I2 (prostacyclin) receptor (IP); K04263 prostacyclin receptor (A)"	Neuroactive ligand-receptor interaction (ko04080);; Vascular smooth muscle contraction (ko04270);; Platelet activation (ko04611)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srx	Prostacyclin receptor (Precursor) GN=PTGIR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: prostacyclin receptor [Ceratotherium simum simum]
ENSG00000160014(CALM3)	--	201.8405982	7876	170.574001	6669	198.8999534	7840	260.03554	10057	244.4900203	9292	223.7021775	8661	0.964474633	0.321777071	normal	0.748931534	0.457003987	normal	0.993522982	0.13536366	normal	0.090840964	0.301934666	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	K02183|3.74885e-103|mze:101482160|calmodulin-like; K02183 calmodulin (A)	Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Phototransduction (ko04744);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916)	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain;; Cytoskeletal-regulatory complex EF hand;; Secreted protein acidic and rich in cysteine Ca binding region;; Ca2+ insensitive EF hand;; Uncharacterised protein family (UPF0154)	Calmodulin GN=CALM3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	Calmodulin [Tupaia chinensis]
ENSG00000160049(DFFA)	--	20.930274	1605	19.87318	1503	24.24913477	1643	20.256944	1582	22.276058	1487	15.169242	1098	0.983869058	-0.0516062	normal	0.983209499	-0.036829664	normal	0.074186652	-0.589077988	normal	0.340078191	-0.211304967	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: apoptotic process (GO:0006915);; 	"K02310|0|hsa:1676|DFFA, DFF-45, DFF1, ICAD; DNA fragmentation factor, 45kDa, alpha polypeptide; K02310 DNA fragmentation factor, 45 kD, alpha subunit (A)"	Apoptosis (ko04210)	--	--	"DNA Fragmentation factor 45kDa, C terminal domain;; CIDE-N domain"	DNA fragmentation factor subunit alpha GN=DFFA OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA fragmentation factor subunit alpha [Equus caballus]
ENSG00000160050(CCDC28B)	--	1.469864	32	1.127237	29	0.906084	20	1.827096	40	2.324264	49	1.072727	23	0.977540609	0.279091991	normal	0.880167443	0.706669205	normal	0.987140429	0.180599947	normal	0.536237726	0.444489343	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4061)	Coiled-coil domain-containing protein 28B GN=CCDC28B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 28B isoform 1 [Dasypus novemcinctus] 
ENSG00000160051(IQCC)	--	1.16229633	62	0.874614664	47	1.042492287	56	1.115792	60	0.9233522	49	1.058362284	57	0.975922975	-0.076217818	normal	0.978092217	0.037512313	normal	0.977273492	0.016794118	normal	0.999834061	-0.01261243	normal	--	--	--	--	--	--	--	--	IQ domain-containing protein C GN=IQCC OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: IQ domain-containing protein C [Trichechus manatus latirostris]
ENSG00000160055(TMEM234)	--	4.21256	55	4.112539	66	3.344608	55	4.084638	60	5.005872	74	4.812322	72	0.976394896	0.092231454	normal	0.970184381	0.140589287	normal	0.948224768	0.371325606	normal	0.755536218	0.206269063	normal	--	--	--	--	--	[X]	--	Uncharacterised protein family UPF0546	Transmembrane protein 234 GN=TMEM234 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 234 [Trichechus manatus latirostris]
ENSG00000160058(BSDC1)	--	13.6478148	927	13.18054091	934	13.92270914	901	13.46046141	921	12.1008605	878	13.47909089	972	0.978011898	-0.040133711	normal	0.972775222	-0.110443688	normal	0.974661863	0.100974559	normal	0.963294031	-0.016418321	normal	--	--	--	--	--	[S]	Function unknown	BSD domain	BSD domain-containing protein 1 GN=BSDC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: BSD domain-containing protein 1 [Vicugna pacos]
ENSG00000160062(ZBTB8A)	--	2.249706042	151	2.083527149	162	1.863362348	158	1.761152717	186	2.814069897	216	2.742374577	215	0.933278171	0.267466263	normal	0.843033251	0.390444854	normal	0.789504672	0.432558158	normal	0.256182841	0.368829531	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10495|0|pon:100461930|ZBTB8A; zinc finger and BTB domain containing 8A; K10495 zinc finger and BTB domain-containing protein 8 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Domain of unknown function (DUF3342);; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 8A GN=ZBTB8A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 8A [Vicugna pacos]
ENSG00000160072(ATAD3B)	--	0.330756	16	0.158835	8	0.290426	14	0.51201	25	0.460196	22	0.305638	15	0.976546515	0.569029139	normal	0.862770199	1.286516976	normal	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K17681|0|hsa:83858|ATAD3B, AAA-TOB3, TOB3; ATPase family, AAA domain containing 3B; K17681 ATPase family AAA domain-containing protein 3A/B (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF3523);; ATPase family associated with various cellular activities (AAA);; AAA domain;; Holliday junction DNA helicase ruvB N-terminus	ATPase family AAA domain-containing protein 3B GN=ATAD3B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ATPase family AAA domain-containing protein 3-like [Odobenus rosmarus divergens]
ENSG00000160075(SSU72)	--	66.851307	1637	60.426052	1516	67.366694	1683	60.87253	1528	60.455922	1487	61.1531	1496	0.978723405	-0.1301156	normal	0.982923207	-0.049242065	normal	0.971973576	-0.178046645	normal	0.569860303	-0.121490835	normal	[K]	Transcription	Molecular Function: phosphoprotein phosphatase activity (GO:0004721);; Cellular Component: nucleus (GO:0005634);; Biological Process: mRNA processing (GO:0006397);; 	K15544|3.03672e-143|tup:102474206|SSU72; SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae); K15544 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16] (A)	mRNA surveillance pathway (ko03015)	[K]	Transcription	Ssu72-like protein	RNA polymerase II subunit A C-terminal domain phosphatase SSU72 GN=SSU72 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [Orcinus orca] 
ENSG00000160087(UBE2J2)	--	18.46721814	568	18.08117413	625	18.88603911	647	19.12900867	643	23.17995831	740	18.80138492	604	0.962616248	0.147719836	normal	0.943915306	0.221748945	normal	0.968883268	-0.107249094	normal	0.744993437	0.08973701	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K04554|9.40625e-180|hsa:118424|UBE2J2, NCUBE-2, NCUBE2, PRO2121; ubiquitin-conjugating enzyme E2, J2 (EC:6.3.2.19); K04554 ubiquitin-conjugating enzyme E2 J2 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; Putative binding domain	Ubiquitin-conjugating enzyme E2 J2 GN=UBE2J2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 J2 isoform X2 [Lipotes vexillifer]
ENSG00000160094(ZNF362)	--	8.62207362	473	10.66140187	527	7.928655717	425	5.035129	275	6.737451236	443	7.837871	420	0.00255228	-0.80974589	normal	0.914372441	-0.271073169	normal	0.969978888	-0.025274486	normal	0.256451241	-0.344659635	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; zinc-finger of a C2HC-type;; C2H2-type zinc finger"	Zinc finger protein 362 GN=ZNF362 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 362 isoformX2 [Canis lupus familiaris] 
ENSG00000160097(FNDC5)	--	0.059668102	3	0.215369309	11	0.056954262	2	0.019787571	1	0.157334705	7	0.059126175	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain	Irisin (Precursor) GN=FNDC5 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: fibronectin type III domain-containing protein 5 [Camelus bactrianus] 
ENSG00000160111(CPAMD8)	--	0.008162429	1	0.242226226	1	0.023578467	2	0.018296076	2	0.029180564	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; Alpha-2-macroglobulin family N-terminal region;; Farnesoic acid 0-methyl transferase;; Alpha-2-macroglobulin family;; A-macroglobulin receptor;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region;; Prenyltransferase-like;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	C3 and PZP-like alpha-2-macroglobulin domain-containing protein 8 (Precursor) GN=CPAMD8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: C3 and PZP-like, alpha-2-macroglobulin domain containing 8 [Sus scrofa]"
ENSG00000160117(ANKLE1)	--	0.231559871	13	0.249102343	13	0.192212	12	0.229435402	14	0.302337733	19	0.321452999	21	--	--	--	--	--	--	0.973152182	0.728891766	normal	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; LEM domain;; Ankyrin repeat	Ankyrin repeat and LEM domain-containing protein 1 GN=ANKLE1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and LEM domain-containing protein 1 [Galeopterus variegatus]
ENSG00000160124(CCDC58)	--	26.46921	197	42.58913	291	30.849257	219	30.634008	254	33.983472	231	34.94312	235	0.884652346	0.333504874	normal	0.857059808	-0.352491758	normal	0.963525326	0.092819586	normal	0.998023824	0.004558669	normal	--	--	--	--	--	[RD]	"General function prediction only;; Cell cycle control, cell division, chromosome partitioning"	Caffeine-induced death protein 2	Coiled-coil domain-containing protein 58 GN=CCDC58 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: coiled-coil domain-containing protein 58 [Orycteropus afer afer]
ENSG00000160131(VMA21)	--	23.86720499	1442	27.02660543	1615	26.77435092	1554	25.336503	1549	20.86010481	1265	25.63700564	1557	0.982332058	0.072359323	normal	0.81294483	-0.373427143	normal	0.984443603	-0.005503651	normal	0.663683138	-0.098376393	normal	--	--	Biological Process: vacuolar proton-transporting V-type ATPase complex assembly (GO:0070072);; 	--	--	[S]	Function unknown	VMA21-like domain	Vacuolar ATPase assembly integral membrane protein VMA21 {ECO:0000255|HAMAP-Rule:MF_03058} OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: vacuolar ATPase assembly integral membrane protein VMA21 isoformX1 [Sus scrofa] 
ENSG00000160145(KALRN)	--	0.947883756	71	1.686882574	99	1.651522044	92	0.404960247	55	0.422609861	64	0.527452444	63	0.945137501	-0.389611483	normal	0.692019733	-0.638552511	normal	0.841044056	-0.543709182	normal	0.233414659	-0.5462929	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K15048|0|hsa:8997|KALRN, ARHGEF24, CHD5, CHDS5, DUET, DUO, HAPIP, TRAD; kalirin, RhoGEF kinase (EC:2.7.11.1); K15048 kalirin [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Protein kinase domain;; Spectrin repeat;; Protein tyrosine kinase;; Divergent CRAL/TRIO domain;; Immunoglobulin I-set domain;; Fibronectin type III domain;; PH domain;; Immunoglobulin domain;; Immunoglobulin domain;; Pleckstrin homology domain;; SH3 domain;; Immunoglobulin V-set domain;; CRAL/TRIO domain;; Variant SH3 domain;; Immunoglobulin domain	Kalirin GN=KALRN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kalirin isoform 1 [Ceratotherium simum simum]
ENSG00000160161(CILP2)	--	0.23161431	18	0.32874622	26	0.15888514	12	0.2187719	17	0.24826824	19	0.22800601	18	--	--	--	0.978572975	-0.443635607	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Mucin-2 protein WxxW repeating region;; Carboxypeptidase regulatory-like domain;; Immunoglobulin domain;; Thrombospondin type 1 domain;; Domain of unknown function (DUF4480);; Immunoglobulin I-set domain	Cartilage intermediate layer protein 2 C2 (Precursor) GN=CILP2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cartilage intermediate layer protein 2 [Leptonychotes weddellii]
ENSG00000160179(ABCG1)	--	0.489807355	39	0.552249874	23	0.214779873	13	1.232969181	75	1.861515779	155	0.41627672	28	0.435783623	0.886988332	normal	3.44E-15	2.654036814	up	0.891539149	1.016393809	normal	0.249946795	1.758998962	normal	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Cellular Component: membrane (GO:0016020);; Molecular Function: ATPase activity (GO:0016887);; 	"K05679|0|ptr:458577|ABCG1; ATP-binding cassette, sub-family G (WHITE), member 1; K05679 ATP-binding cassette, subfamily G (WHITE), member 1 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC-2 type transporter;; ABC transporter;; AAA domain	ATP-binding cassette sub-family G member 1 GN=ABCG1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family G member 1 isoform X1 [Tupaia chinensis]
ENSG00000160180(TFF3)	--	0	0	0.510695437	9	0.747801052	5	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Trefoil factor 3 (Precursor) GN=TFF3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: trefoil factor 3 [Capra hircus]
ENSG00000160181(TFF2)	--	0	0	0	0	0.201363	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Trefoil (P-type) domain	Trefoil factor 2 (Precursor) GN=TFF2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	trefoil factor 2 precursor [Felis catus] 
ENSG00000160182(TFF1)	--	0.576931	3	0.744214	4	1.63652	8	0.72824	4	2.05083	10	0.372514	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Trefoil (P-type) domain	Trefoil factor 1 (Precursor) GN=TFF1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: trefoil factor 1 [Panthera tigris altaica]
ENSG00000160183(TMPRSS3)	--	0.101112104	2	0.021517329	1	0.021250887	0	0.195521068	4	0.147377697	3	0.086935398	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: scavenger receptor activity (GO:0005044);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K09634|0|hsa:64699|TMPRSS3, DFNB10, DFNB8, ECHOS1, TADG12; transmembrane protease, serine 3 (EC:3.4.21.-); K09634 transmembrane protease, serine 3 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain;; Domain of unknown function (DUF1986);; Low-density lipoprotein receptor domain class A	Transmembrane protease serine 3 GN=TMPRSS3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 3 isoform X2 [Tupaia chinensis]
ENSG00000160185(UBASH3A)	--	0	0	0.056232374	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[G]	Carbohydrate transport and metabolism	Histidine phosphatase superfamily (branch 1);; Variant SH3 domain;; SH3 domain	Ubiquitin-associated and SH3 domain-containing protein A GN=UBASH3A OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: ubiquitin-associated and SH3 domain-containing protein A [Galeopterus variegatus]
ENSG00000160188(RSPH1)	--	0.5832911	11	0.504916	16	0.4823276	14	0.506869	13	0.578932	17	0.533167	14	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat	Radial spoke head 1 homolog GN=RSPH1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: radial spoke head 1 homolog [Oryctolagus cuniculus]
ENSG00000160190(SLC37A1)	--	1.917135491	128	1.84694592	122	2.031024361	134	2.835308705	188	2.786018698	184	3.240273355	216	0.665928466	0.518592663	normal	0.561540119	0.565652113	normal	0.196685353	0.674456872	normal	0.049587127	0.594051696	normal	[G]	Carbohydrate transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13783|0|hsa:54020|SLC37A1, G3PP; solute carrier family 37 (glucose-6-phosphate transporter), member 1; K13783 MFS transporter, OPA family, solute carrier family 37 (glycerol-3-phosphate transporter), member 1/2 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Glycerol-3-phosphate transporter GN=SLC37A1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: glycerol-3-phosphate transporter [Tupaia chinensis]
ENSG00000160191(PDE9A)	--	4.135569243	121	2.950003872	63	3.375964368	87	5.438062765	102	5.652147071	136	2.564181851	90	0.945293299	-0.273482346	normal	0.007373913	1.070857039	up	0.971757741	0.039935621	normal	0.663650826	0.254100814	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13761|0|pps:100976834|PDE9A; phosphodiesterase 9A; K13761 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35] (A)"	Purine metabolism (ko00230)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase	"High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A GN=PDE9A OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A, partial [Bos mutus]"
ENSG00000160193(WDR4)	--	11.300307	430	12.210766	498	13.602447	527	9.96048	407	11.734163	463	7.826146	344	0.964285083	-0.109737014	normal	0.96278511	-0.126162652	normal	0.086199924	-0.621461428	normal	0.216499072	-0.282600375	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15443|0|hsa:10785|WDR4, TRM82, TRMT82; WD repeat domain 4; K15443 tRNA (guanine-N(7)-)-methyltransferase subunit TRM82 (A)"	--	[S]	Function unknown	"WD domain, G-beta repeat"	tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4 {ECO:0000255|HAMAP-Rule:MF_03056} OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 [Ceratotherium simum simum]
ENSG00000160194(NDUFV3)	--	8.999364	475	8.775481	470	9.569303	523	11.746658	582	9.921197	471	11.2994689	544	0.920778317	0.26149422	normal	0.970280845	-0.018301431	normal	0.971469094	0.048367126	normal	0.728523975	0.100210461	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; Cellular Component: mitochondrial respiratory chain complex I (GO:0005747);; 	--	--	--	--	--	"NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial (Precursor) GN=NDUFV3 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial-like isoform X1 [Tupaia chinensis]"
ENSG00000160199(PKNOX1)	--	2.296026924	195	2.1836316	190	2.366152	209	3.145608	271	2.4487253	209	3.329247	287	0.733099163	0.441027393	normal	0.960538111	0.115202485	normal	0.709005551	0.446488387	normal	0.234447611	0.347788472	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein PKNOX1 GN=PKNOX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein PKNOX1 isoform X1 [Tupaia chinensis]
ENSG00000160200(CBS)	--	2.602766814	111	2.919978495	128	1.899554574	87	1.03045821	41	0.860101125	38	2.861345356	115	0.000177613	-1.433685242	down	5.19E-07	-1.733607121	down	0.910502031	0.388365654	normal	0.271778041	-0.767382684	normal	[E]	Amino acid transport and metabolism	--	"K01697|0|hsa:875|CBS, HIP4; cystathionine-beta-synthase (EC:4.2.1.22); K01697 cystathionine beta-synthase [EC:4.2.1.22] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Cysteine and methionine metabolism (ko00270);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Pyridoxal-phosphate dependent enzyme;; CBS domain	Cystathionine beta-synthase GN=CBS OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: cystathionine beta-synthase isoform 2 [Odobenus rosmarus divergens]
ENSG00000160201(U2AF1)	--	0.104334069	3	0.10226165	3	0	0	0.102825839	3	0.304707522	8	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: metal ion binding (GO:0046872);; 	K12836|6.08625e-113|lcm:102364147|U2AF1; U2 small nuclear RNA auxiliary factor 1; K12836 splicing factor U2AF 35 kDa subunit (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"Zinc finger C-x8-C-x5-C-x3-H type (and similar);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing factor U2AF 35 kDa subunit GN=U2AF1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: splicing factor U2AF 35 kDa subunit isoform X1 [Echinops telfairi] 
ENSG00000160207(HSF2BP)	--	1.462936644	52	0.683640557	25	1.4294689	51	3.360252289	119	2.364666188	81	2.660669181	95	0.006365486	1.140682365	up	0.000432217	1.617328721	up	0.266412406	0.869950488	normal	0.002563724	1.183166226	up	--	--	--	--	--	--	--	--	Heat shock factor 2-binding protein GN=HSF2BP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: heat shock factor 2-binding protein [Trichechus manatus latirostris]
ENSG00000160208(RRP1B)	--	13.9629	1449	15.3821	1602	16.0297	1664	18.1027	1872	20.2008	2083	15.5325	1612	0.876137988	0.338374198	normal	0.858237125	0.357065785	normal	0.984108378	-0.054045225	normal	0.222174776	0.218258328	normal	--	--	"Biological Process: rRNA processing (GO:0006364);; Cellular Component: preribosome, small subunit precursor (GO:0030688);; "	"K14849|0|hsa:23076|RRP1B, KIAA0179, NNP1L, Nnp1, PPP1R136, RRP1; ribosomal RNA processing 1B; K14849 ribosomal RNA-processing protein 1 (A)"	--	[A]	RNA processing and modification	"Nucleolar protein,Nop52"	Ribosomal RNA processing protein 1 homolog B GN=RRP1B OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: ribosomal RNA processing protein 1 homolog B [Galeopterus variegatus]
ENSG00000160209(PDXK)	--	53.05179611	6618	67.46225971	8762	57.64434516	7360	77.87943172	10070	82.04043002	10504	96.90481565	12631	0.179908164	0.574655355	normal	0.986956903	0.240142246	normal	0.001004968	0.770777412	normal	0.00830858	0.525515175	normal	[H]	Coenzyme transport and metabolism	--	"K00868|0|hsa:8566|PDXK, C21orf124, C21orf97, HEL-S-1a, PKH, PNK; pyridoxal (pyridoxine, vitamin B6) kinase (EC:2.7.1.35); K00868 pyridoxine kinase [EC:2.7.1.35] (A)"	Vitamin B6 metabolism (ko00750)	[H]	Coenzyme transport and metabolism	pfkB family carbohydrate kinase;; Phosphomethylpyrimidine kinase	Pyridoxal kinase GN=PDXK OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: pyridoxal kinase [Equus caballus]
ENSG00000160211(G6PD)	--	702.460053	31308	819.764501	35424	737.299338	32577	495.5460893	21866	553.8914817	24259	539.447425	24372	0.492121987	-0.548641874	normal	0.444679104	-0.567604134	normal	0.927705757	-0.426897554	normal	0.004813817	-0.515265972	normal	--	--	Molecular Function: glucose-6-phosphate dehydrogenase activity (GO:0004345);; Biological Process: glucose metabolic process (GO:0006006);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00036|0|pps:100985592|G6PD; glucose-6-phosphate dehydrogenase; K00036 glucose-6-phosphate 1-dehydrogenase [EC:1.1.1.49] (A)	Pentose phosphate pathway (ko00030);; Glutathione metabolism (ko00480);; Carbon metabolism (ko01200);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	"Glucose-6-phosphate dehydrogenase, C-terminal domain;; Glucose-6-phosphate dehydrogenase, NAD binding domain"	Glucose-6-phosphate 1-dehydrogenase GN=G6PD OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: glucose-6-phosphate 1-dehydrogenase [Galeopterus variegatus] 
ENSG00000160213(CSTB)	--	57.505015	2065	61.8682486	2264	66.488986	2417	56.218551	2050	43.5293231	1558	72.267918	2611	0.986699145	-0.04131928	normal	0.1507272	-0.560151413	normal	0.986232286	0.103031505	normal	0.734776992	-0.137710595	normal	--	--	--	K13907|1.80154e-67|pon:100433135|CSTB; cystatin B (stefin B); K13907 cystatin-A/B (A)	--	--	--	Cystatin domain	Cystatin-B GN=CSTB OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cystatin-B [Galeopterus variegatus]
ENSG00000160216(AGPAT3)	--	21.40322425	1774	22.64331692	1720	19.65071164	1766	31.18239043	2368	26.83993593	2179	22.58668823	2042	0.800658024	0.385540942	normal	0.910016335	0.319580925	normal	0.970311944	0.201045847	normal	0.061062224	0.303378522	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13523|0|hsa:56894|AGPAT3, LPAAT-GAMMA1, LPAAT3; 1-acylglycerol-3-phosphate O-acyltransferase 3 (EC:2.3.1.51); K13523 lysophosphatidic acid acyltransferase / lysophosphatidylinositol acyltransferase [EC:2.3.1.51 2.3.1.-] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	1-acyl-sn-glycerol-3-phosphate acyltransferase gamma GN=AGPAT3 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma isoform X1 [Camelus bactrianus] 
ENSG00000160218(TRAPPC10)	--	10.25553217	655	10.726547	664	9.40907954	600	10.61147079	642	13.55488008	838	11.50481486	722	0.972984342	-0.059612625	normal	0.882820461	0.313703222	normal	0.925748821	0.258150956	normal	0.429258442	0.17754452	normal	--	--	--	--	--	[R]	General function prediction only	"Trafficking protein particle complex subunit 10, TRAPPC10"	Trafficking protein particle complex subunit 10 GN=TRAPPC10 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: trafficking protein particle complex subunit 10, partial [Tupaia chinensis]"
ENSG00000160219(GAB3)	--	0.125672182	12	0.17862709	11	0.085717372	7	0.076243831	7	0.085712619	7	0.013457317	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PH domain	GRB2-associated-binding protein 3 GN=GAB3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: GRB2-associated-binding protein 3 [Ceratotherium simum simum]
ENSG00000160221(C21orf33)	--	0.968075169	16	1.146572487	20	1.242201967	21	1.082853643	19	1.190270842	20	0.98241417	17	--	--	--	0.988106715	-0.019920322	normal	0.986993543	-0.289903763	normal	0.986856116	-0.046755337	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	--	--	--	--	--	DJ-1/PfpI family	"ES1 protein homolog, mitochondrial (Precursor) GN=C21orf33 OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	"PREDICTED: ES1 protein homolog, mitochondrial [Tupaia chinensis]"
ENSG00000160223(ICOSLG)	--	0.824868347	126	0.836092607	134	0.746635729	111	0.645279822	100	0.508890591	79	0.511114489	80	0.915596922	-0.359325098	normal	0.223934789	-0.772248553	normal	0.861909666	-0.473151908	normal	0.16322924	-0.540711624	normal	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	ICOS ligand (Precursor) GN=ICOSLG OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ICOS ligand [Galeopterus variegatus]
ENSG00000160226(C21orf2)	--	3.93720289	137	4.413237335	158	4.1395322	162	4.014371756	171	5.44889	187	3.895215812	170	0.929660099	0.286111496	normal	0.944921617	0.219751952	normal	0.966173211	0.060696338	normal	0.654520284	0.187329912	normal	--	--	--	--	--	[S]	Function unknown	Leucine Rich repeats (2 copies);; Leucine rich repeat	Protein C21orf2 GN=C21orf2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein C21orf2 homolog [Odobenus rosmarus divergens]
ENSG00000160229(ZNF66)	--	0	0	0.39609108	7	0.392296063	2	0	0	0	0	0.0665018	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:100613073|putative zinc finger protein 66; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; SprT-like family;; C1-like domain"	Putative zinc finger protein 66 GN=ZNF66 OS=Homo sapiens (Human) PE=5 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 420-like [Bison bison bison]
ENSG00000160233(LRRC3)	--	1.748732	206	1.265196	163	1.612199	193	1.562595	184	1.446326	172	0.7334954	86	0.950729024	-0.192252551	normal	0.965081381	0.055607784	normal	0.000168587	-1.160491351	down	0.417563393	-0.369487629	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[WT]	Extracellular structures;; Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat N-terminal domain;; Leucine Rich repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 3 (Precursor) GN=LRRC3 OS=Homo sapiens (Human) PE=1 SV=1	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: leucine-rich repeat-containing protein 3 [Odobenus rosmarus divergens]
ENSG00000160255(ITGB2)	--	0.65675665	47	0.603926051	44	0.655070573	41	1.001929155	61	0.697656978	44	1.207867494	82	0.961898387	0.33566305	normal	0.979291171	-0.020714606	normal	0.212132427	0.966039687	normal	0.391889357	0.481956665	normal	--	--	--	"K06464|0|hsa:3689|ITGB2, CD18, LAD, LCAMB, LFA-1, MAC-1, MF17, MFI7; integrin, beta 2 (complement component 3 receptor 3 and 4 subunit); K06464 integrin beta 2 (A)"	Rap1 signaling pathway (ko04015);; Phagosome (ko04145);; Hippo signaling pathway (ko04390);; Cell adhesion molecules (CAMs) (ko04514);; Natural killer cell mediated cytotoxicity (ko04650);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Malaria (ko05144);; Amoebiasis (ko05146);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; HTLV-I infection (ko05166);; Rheumatoid arthritis (ko05323);; Viral myocarditis (ko05416)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; Integrin beta tail domain;; Integrin beta cytoplasmic domain;; EGF-like domain"	Integrin beta-2 (Precursor) GN=ITGB2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin beta-2 [Lipotes vexillifer]
ENSG00000160256(FAM207A)	--	32.91461183	618	29.62329	621	33.37774	665	28.16667	583	29.250686	605	24.60427	476	0.967419839	-0.114649683	normal	0.971775824	-0.05893926	normal	0.418888117	-0.48936252	normal	0.332687579	-0.215957087	normal	--	--	--	--	--	--	--	Ribosome biogenesis protein SLX9	Protein FAM207A GN=FAM207A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM207A [Odobenus rosmarus divergens]
ENSG00000160271(RALGDS)	--	8.175540174	660	7.43505072	600	8.6947544	705	6.652134101	527	5.28235044	423	5.615758957	443	0.820228443	-0.35456931	normal	0.321063304	-0.524149352	normal	0.020622895	-0.676759815	normal	0.004003331	-0.517913809	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: signal transduction (GO:0007165);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K08732|0|ggo:101144743|RALGDS; ral guanine nucleotide dissociation stimulator isoform 1; K08732 ral guanine nucleotide dissociation stimulator (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; Ras association (RalGDS/AF-6) domain	Ral guanine nucleotide dissociation stimulator GN=RALGDS OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ral guanine nucleotide dissociation stimulator isoform X2 [Equus caballus]
ENSG00000160284(SPATC1L)	--	0	0	0	0	0.103362288	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Speriolin C-terminus;; Speriolin N terminus	Speriolin-like protein GN=SPATC1L OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: speriolin-like protein [Equus caballus]
ENSG00000160285(LSS)	--	30.20502544	2251	29.28335449	2326	30.43872779	2354	15.9194321	1159	16.2114638	1197	44.39815681	3188	5.01E-07	-0.987559937	normal	1.13E-06	-0.978950162	normal	0.696484519	0.429008164	normal	0.69230661	-0.340188406	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; 	"K01852|0|hsa:4047|LSS, OSC; lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) (EC:5.4.99.7); K01852 lanosterol synthase [EC:5.4.99.7] (A)"	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	Prenyltransferase-like;; Prenyltransferase and squalene oxidase repeat;; Prenyltransferase-like;; Pectic acid lyase	Lanosterol synthase GN=LSS OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: lanosterol synthase [Oryctolagus cuniculus]
ENSG00000160293(VAV2)	--	14.25797713	1390	12.11914971	1220	13.80423164	1418	15.25455527	1536	18.63969918	1844	10.554413	1084	0.979319175	0.113142073	normal	0.115271151	0.57394845	normal	0.742364066	-0.39530053	normal	0.781719923	0.126516233	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05730|0|hsa:7410|VAV2, VAV-2; vav 2 guanine nucleotide exchange factor; K05730 guanine nucleotide exchange factor VAV (A)"	Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	RhoGEF domain;; Variant SH3 domain;; CAMSAP CH domain;; Variant SH3 domain;; SH3 domain;; SH2 domain;; Calponin homology (CH) domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; PH domain	Guanine nucleotide exchange factor VAV2 GN=VAV2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: uncharacterized protein LOC101408723 [Ceratotherium simum simum]
ENSG00000160294(MCM3AP)	--	15.02986029	2076	15.13253378	2125	14.11483135	1967	15.885579	2198	16.36657991	2249	16.61597901	2291	0.986800028	0.051515625	normal	0.986432327	0.06035251	normal	0.969888934	0.211538226	normal	0.626141107	0.106339406	normal	[UD]	"Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	--	--	--	[UD]	"Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	SAC3/GANP/Nin1/mts3/eIF-3 p25 family	Germinal-center associated nuclear protein GN=MCM3AP OS=Homo sapiens (Human) PE=1 SV=2	DU	"Cell cycle control, cell division, chromosome partitioning;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: 80 kDa MCM3-associated protein [Odobenus rosmarus divergens]
ENSG00000160298(C21orf58)	--	6.942185705	509	6.984158969	530	7.459792	554	6.358826579	456	5.406191187	387	6.451473641	438	0.95078697	-0.188861378	normal	0.522740633	-0.47349719	normal	0.837177179	-0.346181214	normal	0.113635795	-0.335751135	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4587)	Uncharacterized protein C21orf58 GN=C21orf58 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C21orf58 homolog isoform X1 [Tupaia chinensis] 
ENSG00000160299(PCNT)	--	3.983832697	1081	4.138667663	1143	4.863172153	1257	3.874358819	1049	3.715914985	999	5.047658182	1337	0.978212222	-0.074077219	normal	0.954788728	-0.215390275	normal	0.980278217	0.080629304	normal	0.845329298	-0.060623946	normal	--	--	--	"K16481|0|hsa:5116|PCNT, KEN, MOPD2, PCN, PCNT2, PCNTB, PCTN2, SCKL4; pericentrin; K16481 pericentrin (A)"	--	--	--	Pericentrin-AKAP-450 domain of centrosomal targeting protein	Pericentrin GN=PCNT OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: pericentrin [Equus caballus]
ENSG00000160305(DIP2A)	--	6.421678783	777	5.318565462	729	6.455535566	807	6.473518274	811	4.832924213	614	5.016665474	638	0.976467929	0.030895255	normal	0.919653115	-0.26849894	normal	0.834951811	-0.346571504	normal	0.390685453	-0.186916517	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	--	--	[R]	General function prediction only	AMP-binding enzyme;; DMAP1-binding Domain	Disco-interacting protein 2 homolog A GN=DIP2A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: disco-interacting protein 2 homolog A isoform 1 [Odobenus rosmarus divergens]
ENSG00000160310(PRMT2)	--	29.85321	853	34.87850415	1042	35.0526965	954	32.4779924	1001	27.63212076	896	34.40005962	1078	0.956970801	0.199659827	normal	0.94348554	-0.238836973	normal	0.966549483	0.167754261	normal	0.888057186	0.041385179	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: protein binding (GO:0005515);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K11435|0|ptr:458620|PRMT2, HRMT1L1; protein arginine methyltransferase 2; K11435 protein arginine N-methyltransferase 2 [EC:2.1.1.-] (A)"	--	[OKT]	"Posttranslational modification, protein turnover, chaperones;; Transcription;; Signal transduction mechanisms"	Variant SH3 domain;; SH3 domain;; PRMT5 arginine-N-methyltransferase;; Variant SH3 domain;; Methyltransferase small domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Ribosomal protein L11 methyltransferase (PrmA);; Met-10+ like-protein;; Methyltransferase domain	Protein arginine N-methyltransferase 2 GN=PRMT2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: protein arginine N-methyltransferase 2 isoform X1 [Galeopterus variegatus]
ENSG00000160318(CLDND2)	--	2.310427974	10	0.907417932	3	1.678378263	10	2.443130563	9	1.543471483	3	1.25144989	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin family	Claudin domain-containing protein 2 GN=CLDND2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: claudin domain-containing protein 2 [Trichechus manatus latirostris]
ENSG00000160323(ADAMTS13)	--	1.275505385	133	1.113539553	120	1.648154252	140	0.464986767	46	0.851233492	84	1.069792355	102	7.11E-06	-1.531048458	down	0.78412159	-0.528002323	normal	0.833030444	-0.459311861	normal	0.026917416	-0.779108622	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08627|0|hsa:11093|ADAMTS13, ADAM-TS13, ADAMTS-13, C9orf8, VWFCP, vWF-CP; ADAM metallopeptidase with thrombospondin type 1 motif, 13 (EC:3.4.24.87); K08627 a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thrombospondin type 1 domain;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 13 (Precursor) GN=ADAMTS13 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: A disintegrin and metalloproteinase with thrombospondin motifs 13 [Sus scrofa]
ENSG00000160325(CACFD1)	--	4.952160538	241	5.29442999	281	3.348551814	179	2.764001501	134	2.961443933	150	4.447954662	228	0.008164599	-0.870080409	normal	0.002008316	-0.920141089	normal	0.887081718	0.338244954	normal	0.296753273	-0.473527356	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Uncharacterized conserved protein CG6151-P	Calcium channel flower homolog OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: calcium channel flower homolog isoform 2 [Sus scrofa]
ENSG00000160326(SLC2A6)	--	27.90928051	912	26.86246877	947	28.60448954	939	19.55757234	707	19.67520928	742	25.98924715	1040	0.723137124	-0.397393114	normal	0.793126751	-0.372697564	normal	0.971046515	0.138882406	normal	0.524567328	-0.188856904	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08144|0|pps:100983806|SLC2A6; solute carrier family 2 (facilitated glucose transporter), member 6; K08144 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 6 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 6 GN=SLC2A6 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 6 isoform X2 [Equus przewalskii]"
ENSG00000160336(ZNF761)	--	15.26684779	939	17.4301797	1076	16.88533615	1066	15.7075769	1083	15.497619	1026	18.3657672	1271	0.964870104	0.174737533	normal	0.976564131	-0.089944429	normal	0.944691387	0.245146269	normal	0.622427871	0.112957024	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:388561|ZNF761, ZNF468; zinc finger protein 761; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger double-stranded RNA-binding;; BolA-like protein;; Restriction endonuclease fold toxin 7"	Zinc finger protein 761 GN=ZNF761 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 665-like [Ursus maritimus]
ENSG00000160345(C9orf116)	--	11.27628	108	9.70098	93	9.18819	91	12.340117	104	13.53941	126	11.416771	96	0.968778563	-0.084061252	normal	0.887101624	0.410934379	normal	0.970532874	0.067779648	normal	0.812680279	0.137470839	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4490)	UPF0691 protein C9orf116 GN=C9orf116 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0691 protein C9orf116 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000160352(ZNF714)	--	3.570550013	341	3.628602604	401	2.918882465	340	2.697078084	342	3.008168919	387	2.967314259	293	0.968230071	-0.026488505	normal	0.966382004	-0.072417204	normal	0.939000431	-0.221861456	normal	0.757453292	-0.104016593	normal	[R]	General function prediction only	--	K09228|0|hsa:148206|ZNF714; zinc finger protein 714; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; Transposase zinc-ribbon domain;; C1-like domain;; SprT-like family"	Zinc finger protein 714 GN=ZNF714 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000160360(GPSM1)	--	11.41675537	766	9.02177281	632	9.606603964	680	8.152678013	549	7.367266774	525	5.427934218	380	0.319936552	-0.510155539	normal	0.903122435	-0.288275613	normal	0.000432962	-0.845275953	normal	0.005631538	-0.537365103	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: GTPase regulator activity (GO:0030695);; 	K15839|0|pon:100444986|GPSM1; G-protein signaling modulator 1; K15839 G-protein signaling modulator 1 (A)	Cocaine addiction (ko05030)	[T]	Signal transduction mechanisms	GoLoco motif;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Rapsyn N-terminal myristoylation and linker region	G-protein-signaling modulator 1 GN=GPSM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein-signaling modulator 1 [Vicugna pacos]
ENSG00000160392(C19orf47)	--	15.807663	618	16.15142	630	18.2059343	675	18.654485	651	16.1683581	627	13.769742	547	0.973435314	0.044111589	normal	0.973238777	-0.028244981	normal	0.881550649	-0.310862943	normal	0.723241561	-0.097007951	normal	--	--	--	--	--	[S]	Function unknown	--	Uncharacterized protein C19orf47 GN=C19orf47 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C19orf47 homolog isoform X1 [Tupaia chinensis]
ENSG00000160401(CFAP157)	--	0.044508101	2	0.090708102	4	0	0	0.163129221	7	0.160229	6	0.110451271	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf117 GN=C9orf117 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf117 homolog [Leptonychotes weddellii]
ENSG00000160404(TOR2A)	--	7.77753	190	5.45851106	136	5.615177	142	8.153233	206	8.807504	216	9.356831	236	0.964275013	0.085151283	normal	0.284884197	0.640302102	normal	0.094884013	0.718606523	normal	0.115545795	0.470632765	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	[R]	General function prediction only	Torsin	Torsin-2A (Precursor) GN=TOR2A OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: torsin-2A [Chrysochloris asiatica]
ENSG00000160408(ST6GALNAC6)	--	13.147569	589	11.8014717	528	14.3183068	622	13.78597634	585	13.67697695	597	10.77644981	449	0.972702032	-0.040557116	normal	0.959765898	0.155347811	normal	0.474278302	-0.477119006	normal	0.676356303	-0.114158851	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03376|0|hsa:30815|ST6GALNAC6, SIAT7-F, SIAT7F, ST6GALNACVI; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6; K03376 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7F) [EC:2.4.99.-] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 GN=ST6GALNAC6 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 isoform X1 [Loxodonta africana]"
ENSG00000160410(SHKBP1)	--	88.580754	3414	64.33897473	2661	82.725328	3320	70.00063	2715	78.44673633	3154	68.76629815	2603	0.877723792	-0.36116039	normal	0.972788155	0.223670719	normal	0.878908886	-0.359114155	normal	0.452891194	-0.170197167	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	SH3KBP1-binding protein 1 GN=SHKBP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: SH3KBP1-binding protein 1 isoform X2 [Tupaia chinensis]
ENSG00000160439(RDH13)	--	6.598741	286	5.978017689	257	7.156379797	294	6.489052818	284	6.621209996	286	5.119301	234	0.966872761	-0.040736866	normal	0.958312242	0.132083221	normal	0.874076302	-0.335659392	normal	0.841523796	-0.079570554	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K11161|0|hsa:112724|RDH13, SDR7C3; retinol dehydrogenase 13 (all-trans/9-cis) (EC:1.1.1.-); K11161 retinol dehydrogenase 13 [EC:1.1.1.300] (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; NAD dependent epimerase/dehydratase family	Retinol dehydrogenase 13 GN=RDH13 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: retinol dehydrogenase 13 [Ceratotherium simum simum]
ENSG00000160445(ZER1)	--	10.79356918	846	9.564063314	759	10.87812302	868	10.80462365	868	13.19070369	922	11.59436067	940	0.977733187	0.006194011	normal	0.930047705	0.258771887	normal	0.973674487	0.106495935	normal	0.602806052	0.121870081	normal	--	--	--	"K10350|0|hsa:10444|ZER1, C9orf60, ZYG, ZYG11BL; zyg-11 related, cell cycle regulator; K10350 Zyg-11 protein homolog (A)"	--	[R]	General function prediction only	Armadillo/beta-catenin-like repeat;; V-ATPase subunit H	Protein zer-1 homolog GN=ZER1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein zer-1 homolog [Trichechus manatus latirostris]
ENSG00000160446(ZDHHC12)	--	75.80385467	987	77.29141809	1021	75.34120992	997	60.495786	788	60.8933716	788	69.29427728	867	0.822679682	-0.355066584	normal	0.743023023	-0.394474747	normal	0.954174602	-0.209511866	normal	0.067165482	-0.319643071	normal	--	--	--	"K18932|5.46294e-96|pps:100978942|ZDHHC12; zinc finger, DHHC-type containing 12; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC12 GN=ZDHHC12 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	Putative palmitoyltransferase ZDHHC12 [Bos mutus]
ENSG00000160447(PKN3)	--	9.54464	663	7.59716	535	8.46471	602	7.70672	531	8.98723	617	7.53806	524	0.827549765	-0.350220187	normal	0.95365793	0.183820876	normal	0.946720307	-0.20792777	normal	0.624851727	-0.127511357	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; 	K06071|0|hsa:29941|PKN3; protein kinase N3 (EC:2.7.11.13); K06071 protein kinase N [EC:2.7.11.13] (A)	PI3K-Akt signaling pathway (ko04151);; Salmonella infection (ko05132)	[T]	Signal transduction mechanisms	Protein kinase domain;; Hr1 repeat;; Protein tyrosine kinase;; Protein kinase C terminal domain	Serine/threonine-protein kinase N3 GN=PKN3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase N3 isoform 1 [Trichechus manatus latirostris]
ENSG00000160460(SPTBN4)	--	1.719970121	86	0.85598592	66	1.074194257	78	1.03090092	67	1.0539739	90	0.98778091	64	0.93441865	-0.383228381	normal	0.917778049	0.417805818	normal	0.958062219	-0.287529191	normal	0.916858359	-0.078629528	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K06115|0|hsa:57731|SPTBN4, QV, SPNB4, SPTBN3; spectrin, beta, non-erythrocytic 4; K06115 spectrin beta (A)"	--	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Pleckstrin homology domain;; PH domain;; CAMSAP CH domain	"Spectrin beta chain, non-erythrocytic 4 GN=SPTBN4 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"spectrin beta chain, non-erythrocytic 4 [Bos taurus] "
ENSG00000160469(BRSK1)	--	4.59828983	220	2.841309621	152	4.211646197	167	3.914241466	165	3.756153491	163	1.734320056	83	0.766521587	-0.442289175	normal	0.964290048	0.078618666	normal	0.00550838	-1.003800818	down	0.397859629	-0.414129422	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08796|0|hsa:84446|BRSK1, hSAD1; BR serine/threonine kinase 1 (EC:2.7.11.1 2.7.11.26); K08796 BR serine/threonine kinase [EC:2.7.11.1] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Serine/threonine-protein kinase BRSK1 GN=BRSK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	TPA: BR serine/threonine-protein kinase 1-like [Bos taurus]
ENSG00000160471(COX6B2)	--	0.534443761	18	0.230965599	8	0.247106264	7	0.220651101	5	0.513605756	18	0.343554333	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K02267|6.55888e-61|hsa:125965|COX6B2, COXVIB2, CT59; cytochrome c oxidase subunit VIb polypeptide 2 (testis); K02267 cytochrome c oxidase subunit 6b (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome oxidase c subunit VIb	Cytochrome c oxidase subunit 6B2 GN=COX6B2 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: cytochrome c oxidase subunit 6B2 [Galeopterus variegatus] 
ENSG00000160472(TMEM190)	--	1.47243	10	0.558684	4	0.411774	2	0.701984	5	0.430772	2	0.431058	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 190	Transmembrane protein 190 (Precursor) GN=TMEM190 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 190 [Trichechus manatus latirostris]
ENSG00000160505(NLRP4)	--	0	0	0	0	0	0	0.016514415	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	NACHT domain;; PAAD/DAPIN/Pyrin domain;; Leucine Rich repeat	"NACHT, LRR and PYD domains-containing protein 4 GN=NLRP4 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: NACHT, LRR and PYD domains-containing protein 4 [Ceratotherium simum simum]"
ENSG00000160539(PLPP7)	--	0.0754429	2	0.136218131	2	0.0282663	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	PAP2 superfamily	Probable lipid phosphate phosphatase PPAPDC3 GN=PPAPDC3 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: probable lipid phosphate phosphatase PPAPDC3 [Lipotes vexillifer]
ENSG00000160551(TAOK1)	--	24.61797035	5025	27.332508	5582	25.35090003	5075	27.451038	5623	26.638083	5415	23.82374261	4871	0.991056736	0.13134621	normal	0.993127699	-0.065229401	normal	0.992726735	-0.06746076	normal	1	-0.000969156	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04429|0|ptr:454548|TAOK1; TAO kinase 1; K04429 thousand and one amino acid protein kinase [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase TAO1 GN=TAOK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase TAO1 isoform X1 [Condylura cristata] 
ENSG00000160563(MED27)	--	23.263688	461	17.90394163	371	21.37901946	459	17.08344343	364	19.26242759	431	14.54836607	333	0.803524828	-0.370268021	normal	0.947263661	0.194107497	normal	0.55006868	-0.46943953	normal	0.402534623	-0.215826489	normal	--	--	--	K15170|0|pps:100972519|MED27; mediator complex subunit 27; K15170 mediator of RNA polymerase II transcription subunit 27 (A)	Thyroid hormone signaling pathway (ko04919)	--	--	Mediator complex subunit 27	Mediator of RNA polymerase II transcription subunit 27 GN=MED27 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	mediator of RNA polymerase II transcription subunit 27 [Sus scrofa] 
ENSG00000160570(DEDD2)	--	26.02190201	741	27.98341676	843	37.26517848	1109	43.20254789	1289	39.5719672	1133	42.01434113	1218	0.001161397	0.766655101	normal	0.717959677	0.404488821	normal	0.974926211	0.126798283	normal	0.047035725	0.413919665	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	--	--	--	--	Death effector domain	DNA-binding death effector domain-containing protein 2 GN=DEDD2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-binding death effector domain-containing protein 2-like isoform X1 [Camelus ferus] 
ENSG00000160584(SIK3)	--	5.43340421	598	5.429569844	641	5.599659	634	4.0134803	458	3.4495109	404	4.072017166	459	0.68777384	-0.414409361	normal	0.02263211	-0.685339801	normal	0.487532021	-0.47294833	normal	0.004000373	-0.524932556	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K16311|0|mcf:102145089|SIK3; SIK family kinase 3; K19009 serine/threonine-protein kinase SIK3 [EC:2.7.11.1] (A)	--	--	--	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase SIK3 GN=SIK3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase SIK3 isoform X2 [Oryctolagus cuniculus]
ENSG00000160588(MPZL3)	--	0.218400422	12	0.252269795	14	0.166480796	8	0.2361511	13	0.44721265	24	0.730487231	29	--	--	--	0.967480046	0.698033852	normal	0.307576709	1.674099268	normal	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain	Myelin protein zero-like protein 3 (Precursor) GN=MPZL3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: myelin protein zero-like protein 3 isoform X1 [Camelus ferus] 
ENSG00000160602(NEK8)	--	2.878714	145	1.7215	130	2.698515	119	1.525968	84	2.125154	109	4.09255	199	0.126039503	-0.80704186	normal	0.941115141	-0.272147574	normal	0.132713233	0.726302241	normal	0.984154445	-0.026191537	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08857|0|hsa:284086|NEK8, JCK, NEK12A, NPHP9, RHPD2; NIMA-related kinase 8 (EC:2.7.11.1); K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Regulator of chromosome condensation (RCC1) repeat;; Protein tyrosine kinase;; Regulator of chromosome condensation (RCC1) repeat	Serine/threonine-protein kinase Nek8 GN=NEK8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Nek8 [Leptonychotes weddellii]
ENSG00000160606(TLCD1)	--	38.6463227	466	31.905993	394	34.73629	433	20.33131696	256	20.551762	254	23.983769	302	0.000420408	-0.890991768	normal	0.087997905	-0.651652028	normal	0.366656631	-0.525898406	normal	0.000643189	-0.69183445	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	TLC domain	Calfacilitin (Precursor) GN=TLCD1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: TLC domain-containing protein 1 [Ochotona princeps]
ENSG00000160613(PCSK7)	--	4.788357866	404	5.24577731	352	5.90311229	484	8.751088658	811	9.081619828	857	5.966905	529	8.38E-06	0.971856182	normal	8.25E-10	1.258716559	up	0.965008869	0.119611647	normal	0.019599467	0.803445727	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K08673|0|hsa:9159|PCSK7, LPC, PC7, PC8, SPC7; proprotein convertase subtilisin/kexin type 7 (EC:3.4.21.-); K08673 proprotein convertase subtilisin/kexin type 7 [EC:3.4.21.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family;; Proprotein convertase P-domain	Proprotein convertase subtilisin/kexin type 7 (Precursor) GN=PCSK7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proprotein convertase subtilisin/kexin type 7 [Ceratotherium simum simum]
ENSG00000160633(SAFB)	--	28.417238	1600	25.14269672	1707	23.55925353	1672	26.77806	1830	30.220368	2069	28.59113255	1744	0.975683091	0.162793234	normal	0.952483864	0.25583789	normal	0.98459089	0.052487265	normal	0.415458863	0.159363096	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[K]	Transcription	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; SAP domain"	Scaffold attachment factor B1 GN=SAFB OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: scaffold attachment factor B1 [Camelus ferus]
ENSG00000160678(S100A1)	--	0.4370033	4	0.176978	3	0.114472	1	0.256341	2	0.116854	1	0.443642	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	S-100/ICaBP type calcium binding domain;; EF hand;; EF-hand domain pair	Protein S100-A1 GN=S100A1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	"Protein S100-A1, partial [Bos mutus]"
ENSG00000160679(CHTOP)	--	44.79745238	1619	43.54726801	1602	43.71576773	1615	40.6420544	1508	46.29072359	1629	44.68915206	1622	0.978231894	-0.133167833	normal	0.984431411	0.002683386	normal	0.984853715	-0.002049872	normal	0.870341458	-0.044093508	normal	--	--	--	--	--	--	--	C-terminal duplication domain of Friend of PRMT1	Chromatin target of PRMT1 protein GN=CHTOP OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: chromatin target of PRMT1 protein isoform X1 [Erinaceus europaeus]
ENSG00000160685(ZBTB7B)	--	18.63985088	1321	18.15132429	1317	19.18307826	1404	16.10812069	1135	16.11734123	1144	17.88177224	1278	0.943613651	-0.24945704	normal	0.95465782	-0.224318209	normal	0.974826128	-0.143784146	normal	0.268922003	-0.205137143	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10494|0|cjc:100389139|ZBTB7B; zinc finger and BTB domain containing 7B; K10494 zinc finger and BTB domain-containing protein 7 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 7B GN=ZBTB7B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 7B isoform 1 [Ceratotherium simum simum] 
ENSG00000160688(FLAD1)	--	24.80799741	776	19.47225977	617	23.16619201	755	26.84888508	851	29.99096236	944	25.12887409	785	0.972608066	0.102077186	normal	0.098454569	0.59091072	normal	0.975649407	0.047830606	normal	0.21382058	0.243223759	normal	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K00953|0|lve:103074144|FLAD1; flavin adenine dinucleotide synthetase 1; K00953 FAD synthetase [EC:2.7.7.2] (A)	Riboflavin metabolism (ko00740)	[EH]	Amino acid transport and metabolism;; Coenzyme transport and metabolism	Probable molybdopterin binding domain;; Phosphoadenosine phosphosulfate reductase family	FAD synthase region (Precursor) GN=FLAD1 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: FAD synthase isoform X1 [Physeter catodon]
ENSG00000160691(SHC1)	--	101.97393	6493	94.387588	6146	100.098825	6507	107.0527546	6898	102.5606669	6519	86.686519	5576	0.994454197	0.056447696	normal	0.993878989	0.063561164	normal	0.982815561	-0.230995378	normal	0.909622586	-0.033311789	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06279|0|hsa:6464|SHC1, SHC, SHCA; SHC (Src homology 2 domain containing) transforming protein 1; K06279 SHC- transforming protein 1 (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Alcoholism (ko05034);; Bacterial invasion of epithelial cells (ko05100);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; SH2 domain	SHC-transforming protein 1 GN=SHC1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	SHC-transforming protein 1 isoform 3 [Camelus ferus]
ENSG00000160695(VPS11)	--	4.540204705	314	4.537963001	286	3.665685532	268	5.124188	322	5.059107569	348	4.689021635	342	0.968093228	0.005437592	normal	0.92165242	0.260395706	normal	0.860442839	0.341760726	normal	0.501758254	0.200284916	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Vacuolar protein sorting protein 11 C terminal;; Region in Clathrin and VPS;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	Vacuolar protein sorting-associated protein 11 homolog GN=VPS11 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 11 homolog [Ailuropoda melanoleuca]
ENSG00000160703(NLRX1)	--	8.518503931	577	8.339942439	582	9.233533557	640	7.575836261	513	9.042791622	597	10.07069927	671	0.948773687	-0.199879856	normal	0.97274436	0.015246106	normal	0.973200119	0.059811382	normal	0.913836245	-0.034696259	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12653|0|hsa:79671|NLRX1, CLR11.3, DLNB26, NOD26, NOD5, NOD9; NLR family member X1; K12653 NLR family member X1 (A)"	RIG-I-like receptor signaling pathway (ko04622);; Influenza A (ko05164)	[S]	Function unknown	NACHT domain;; Leucine Rich repeat	NLR family member X1 (Precursor) GN=NLRX1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: NLR family member X1 [Galeopterus variegatus]
ENSG00000160710(ADAR)	--	44.12802	6162	46.11834	6414	46.83668	6481	46.28019	6420	49.84005	6936	48.23013	6751	0.994451734	0.02833543	normal	0.993592118	0.091432253	normal	0.99444231	0.050581778	normal	0.835015996	0.056415215	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: double-stranded RNA adenosine deaminase activity (GO:0003726);; Molecular Function: adenosine deaminase activity (GO:0004000);; Biological Process: RNA processing (GO:0006396);; 	K12968|0|ggo:101134621|ADAR; double-stranded RNA-specific adenosine deaminase isoform 1; K12968 double-stranded RNA-specific adenosine deaminase [EC:3.5.4.37] (A)	Cytosolic DNA-sensing pathway (ko04623);; Measles (ko05162);; Influenza A (ko05164)	[A]	RNA processing and modification	Adenosine-deaminase (editase) domain;; Adenosine deaminase z-alpha domain;; Double-stranded RNA binding motif;; double strand RNA binding domain from DEAD END PROTEIN 1	Double-stranded RNA-specific adenosine deaminase GN=ADAR OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: double-stranded RNA-specific adenosine deaminase isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000160712(IL6R)	--	3.308407551	314	3.707283973	359	5.5684202	279	3.006802256	307	2.817386861	276	3.50094822	339	0.966238122	-0.063046162	normal	0.774460568	-0.398820016	normal	0.916959291	0.271392211	normal	0.864035842	-0.067491371	normal	--	--	--	"K05055|0|hsa:3570|IL6R, CD126, IL-6R-1, IL-6RA, IL6Q, IL6RA, IL6RQ, gp80; interleukin 6 receptor; K05055 interleukin 6 receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; HIF-1 signaling pathway (ko04066);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	--	--	"Interleukin-6 receptor alpha chain, binding;; Immunoglobulin domain"	Interleukin-6 receptor subunit alpha (Precursor) GN=IL6R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-6 receptor subunit alpha [Vicugna pacos]
ENSG00000160714(UBE2Q1)	--	20.429	1236	20.3625	1247	21.2735	1293	20.629	1255	24.4414	1469	22.6381	1371	0.982016688	-0.008812771	normal	0.959927483	0.214706255	normal	0.980850101	0.076128375	normal	0.678257533	0.096208019	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10582|0|ssc:100156747|UBE2Q1; ubiquitin-conjugating enzyme E2Q family member 1; K10582 ubiquitin-conjugating enzyme E2 Q [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; RWD domain	Ubiquitin-conjugating enzyme E2 Q1 GN=UBE2Q1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: ubiquitin-conjugating enzyme E2 Q1, partial [Lipotes vexillifer]"
ENSG00000160716(CHRNB2)	--	0.182637796	21	0.337775839	31	0.218624217	25	0.2686796	31	0.127090163	14	0.231107192	27	0.973022028	0.500742887	normal	0.808296456	-1.087457609	normal	0.985923298	0.097087557	normal	0.922328036	-0.119018149	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04813|0|ptr:740303|CHRNB2; cholinergic receptor, nicotinic, beta 2 (neuronal); K04813 nicotinic acetylcholine receptor beta-2 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Neuronal acetylcholine receptor subunit beta-2 (Precursor) GN=CHRNB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuronal acetylcholine receptor subunit beta-2 [Sus scrofa]
ENSG00000160741(CRTC2)	--	10.37757	509	11.81377	549	10.51176	511	13.68708	610	12.6772	607	13.57088	587	0.937923765	0.229677373	normal	0.965291507	0.123141125	normal	0.951672781	0.191217387	normal	0.453393299	0.179981936	normal	--	--	Molecular Function: cAMP response element binding protein binding (GO:0008140);; Biological Process: protein homotetramerization (GO:0051289);; 	"K16333|0|hsa:200186|CRTC2, TORC-2, TORC2; CREB regulated transcription coactivator 2; K16333 CREB-regulated transcription coactivator 2 (A)"	PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; HTLV-I infection (ko05166)	--	--	"Transducer of regulated CREB activity middle domain;; Transducer of regulated CREB activity, C terminus;; Transducer of regulated CREB activity, N terminus"	CREB-regulated transcription coactivator 2 GN=CRTC2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CREB-regulated transcription coactivator 2 [Equus przewalskii]
ENSG00000160746(ANO10)	--	20.02173811	742	22.66380524	820	14.86398	676	17.62352947	736	18.52253691	760	20.583956	787	0.975275797	-0.042457411	normal	0.968425223	-0.130800399	normal	0.949507539	0.210611888	normal	0.985893701	0.007466223	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Calcium-activated chloride channel	Anoctamin-10 GN=ANO10 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anoctamin-10 [Oryctolagus cuniculus]
ENSG00000160752(FDPS)	--	186.2768422	3987	157.991432	3436	209.8123256	4568	86.99618386	1905	85.79564752	1811	130.992613	2804	4.03E-09	-1.095719239	down	2.95E-06	-0.944787	normal	0.003748037	-0.712063796	normal	0.000318469	-0.89864119	normal	[H]	Coenzyme transport and metabolism	Biological Process: isoprenoid biosynthetic process (GO:0008299);; 	K00787|0|ptr:457366|FDPS; farnesyl diphosphate synthase; K00787 farnesyl diphosphate synthase [EC:2.5.1.1 2.5.1.10] (A)	Terpenoid backbone biosynthesis (ko00900);; Influenza A (ko05164);; HTLV-I infection (ko05166)	[H]	Coenzyme transport and metabolism	Polyprenyl synthetase	Farnesyl pyrophosphate synthase GN=FDPS OS=Homo sapiens (Human) PE=1 SV=4	H	Coenzyme transport and metabolism	PREDICTED: farnesyl pyrophosphate synthase [Oryctolagus cuniculus]
ENSG00000160753(RUSC1)	--	25.05665689	771	21.9884395	713	28.43422165	897	30.39539486	892	25.46676964	778	20.875356	680	0.960617071	0.179148474	normal	0.970763743	0.104229843	normal	0.696638411	-0.407073829	normal	0.902047384	-0.04055881	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	RUN domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	RUN and SH3 domain-containing protein 1 GN=RUSC1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: RUN and SH3 domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000160767(FAM189B)	--	30.41545675	1291	26.03045431	1206	31.60112815	1419	26.57369535	1183	25.4561878	1093	24.90152509	1121	0.971617367	-0.156676312	normal	0.969061256	-0.163148057	normal	0.848821774	-0.347961517	normal	0.213702534	-0.22624992	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	CD20-like family	Protein FAM189B GN=FAM189B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM189B [Galeopterus variegatus]
ENSG00000160781(PAQR6)	--	4.509609105	143	3.768838655	123	3.587594991	117	4.563102736	142	5.148282035	156	6.049800964	189	0.967705968	-0.040519594	normal	0.919061577	0.317982669	normal	0.250210599	0.676641767	normal	0.392553769	0.326056699	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Progestin and adipoQ receptor family member 6 GN=PAQR6 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: progestin and adipoQ receptor family member 6 isoform X4 [Bison bison bison]
ENSG00000160783(PMF1)	--	24.713523	467	25.207759	486	22.850975	446	22.650666	434	22.43866942	423	22.411331	429	0.961367744	-0.136095146	normal	0.939247749	-0.220987428	normal	0.968708558	-0.06413575	normal	0.608250354	-0.142860992	normal	--	--	--	K11546|2.85941e-130|ptr:457388|PMF1; polyamine-modulated factor 1; K11546 polyamine-modulated factor 1 (A)	--	--	--	Nnf1	Polyamine-modulated factor 1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: polyamine-modulated factor 1 isoform X2 [Galeopterus variegatus]
ENSG00000160785(SLC25A44)	--	13.599684	883	14.8649269	960	13.275956	856	15.94720833	1027	17.19469	1104	17.09472	1112	0.961044222	0.186816958	normal	0.963846998	0.179942807	normal	0.799464525	0.368609728	normal	0.186289457	0.24382735	normal	--	--	--	"K15121|0|hsa:9673|SLC25A44; solute carrier family 25, member 44; K15121 solute carrier family 25, member 44 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 44 GN=SLC25A44 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 44 isoform X1 [Camelus ferus]
ENSG00000160789(LMNA)	--	206.43931	10324	250.769875	13047	239.217027	12558	248.891181	12774	214.8191681	10185	195.316642	9721	0.983390441	0.276339018	normal	0.937810042	-0.378648876	normal	0.933272929	-0.377669682	normal	0.550414871	-0.158747888	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	K12641|0|ggo:101139250|LMNA; prelamin-A/C; K12641 lamin A/C (A)	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[DY]	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	Intermediate filament protein;; Lamin Tail Domain	Lamin-A/C (Precursor) GN=LMNA OS=Homo sapiens (Human) PE=1 SV=1	DY	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	PREDICTED: lamin [Camelus dromedarius]
ENSG00000160796(NBEAL2)	--	10.543974	1590	8.869725	1544	11.246028	1832	12.068678	1865	16.909321	2630	11.228078	1772	0.96888968	0.199138788	normal	0.001819555	0.746397088	normal	0.985018272	-0.056285096	normal	0.352424043	0.314855829	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; PH domain associated with Beige/BEACH;; WD domain, G-beta repeat;; Concanavalin A-like lectin/glucanases superfamily"	Neurobeachin-like protein 2 GN=NBEAL2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: neurobeachin-like 2 [Equus caballus]
ENSG00000160799(CCDC12)	--	16.20689	347	20.39614939	449	17.31930113	381	18.9587113	409	21.8292821	458	18.74437025	399	0.944257801	0.205494148	normal	0.970040734	0.007181646	normal	0.968078584	0.058081014	normal	0.800328473	0.083837691	normal	--	--	--	K12871|6.20512e-85|ggo:101132501|CCDC12; coiled-coil domain-containing protein 12; K12871 coiled-coil domain-containing protein 12 (A)	Spliceosome (ko03040)	[S]	Function unknown	cwf18 pre-mRNA splicing factor	Coiled-coil domain-containing protein 12 GN=CCDC12 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	coiled-coil domain-containing protein 12-like protein [Camelus ferus]
ENSG00000160801(PTH1R)	--	0.824167161	26	0.628758066	20	0.633465387	20	0.11511267	3	0.214823558	6	0.062960429	2	0.013327276	-2.626459099	normal	0.781819671	-1.536354643	normal	0.097094548	-2.620893773	normal	0.000210092	-2.606692147	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04585|0|hsa:5745|PTH1R, PFE, PTHR, PTHR1; parathyroid hormone 1 receptor; K04585 parathyroid hormone receptor 1 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Endocrine and other factor-regulated calcium reabsorption (ko04961)	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Hormone receptor domain	Parathyroid hormone/parathyroid hormone-related peptide receptor (Precursor) GN=PTH1R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: parathyroid hormone/parathyroid hormone-related peptide receptor isoform X1 [Galeopterus variegatus]
ENSG00000160803(UBQLN4)	--	31.0596	2330	27.8285	2106	29.3877	2231	25.0583	1866	24.9499	1855	21.8376	1648	0.869976626	-0.350954	normal	0.970198094	-0.204356322	normal	0.596963279	-0.444913424	normal	0.035169427	-0.333882249	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K04523|0|hsa:56893|UBQLN4, A1U, A1Up, C1orf6, CIP75, UBIN; ubiquilin 4; K04523 ubiquilin (A)"	Protein processing in endoplasmic reticulum (ko04141)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; UBA/TS-N domain;; Ubiquitin-2 like Rad60 SUMO-like	Ubiquilin-4 GN=UBQLN4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquilin-4 [Vicugna pacos]
ENSG00000160813(PPP1R35)	--	28.20646	407	24.5555	376	30.38155	466	31.04483	458	30.5618	451	25.54486	374	0.960535597	0.138991741	normal	0.930738757	0.240085524	normal	0.86868031	-0.324405502	normal	0.970604033	0.017339503	normal	--	--	--	"K17574|1.17263e-105|hsa:221908|PPP1R35, C7orf47; protein phosphatase 1, regulatory subunit 35; K17574 protein phosphatase 1 regulatory subunit 35 (A)"	--	--	--	Protein phosphatase 1 regulatory subunit 35 C-terminus	Protein phosphatase 1 regulatory subunit 35 GN=PPP1R35 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 35 [Tupaia chinensis] 
ENSG00000160818(GPATCH4)	--	16.4204797	923	14.874924	886	18.06368016	1068	19.00980589	1103	19.04836716	1098	16.76721454	960	0.949673972	0.225853716	normal	0.914340965	0.287631159	normal	0.967663145	-0.161854917	normal	0.617986668	0.114561163	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[AD]	"RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	G-patch domain	G patch domain-containing protein 4 GN=GPATCH4 OS=Homo sapiens (Human) PE=1 SV=2	AD	"RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: G patch domain-containing protein 4 isoform X1 [Galeopterus variegatus]
ENSG00000160838(LRRC71)	--	0.0260864	1	0	0	0.0748911	2	0.0257876	1	0.0504551	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine Rich repeat	Leucine-rich repeat-containing protein 71 GN=LRRC71 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 71 [Leptonychotes weddellii]
ENSG00000160867(FGFR4)	--	12.93308485	688	8.4175058	444	9.939854247	550	5.946125384	335	10.088695	532	8.464822777	484	7.78E-07	-1.065591515	down	0.932343766	0.23869645	normal	0.950741982	-0.192152381	normal	0.427745996	-0.336148429	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05095|0|ggo:101145205|FGFR4; fibroblast growth factor receptor 4 isoform 1; K05095 fibroblast growth factor receptor 4 [EC:2.7.10.1] (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Fibroblast growth factor receptor 4 (Precursor) GN=FGFR4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor receptor 4 isoform X1 [Loxodonta africana]
ENSG00000160868(CYP3A4)	--	0	0	0.024852342	1	0	0	0.076928664	3	0.120585028	4	0.0253567	1	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17689|0|hsa:1576|CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1; cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157); K17689 cytochrome P450, family 3, subfamily A, polypeptide 4 [EC:1.14.13.32 1.14.13.67 1.14.13.97 1.14.13.157 1.14.13.-] (A)"	Steroid hormone biosynthesis (ko00140);; Linoleic acid metabolism (ko00591);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Bile secretion (ko04976);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 3A4 GN=CYP3A4 OS=Homo sapiens (Human) PE=1 SV=4	Q	"Secondary metabolites biosynthesis, transport and catabolism"	cytochrome P450 3A89 [Equus caballus] 
ENSG00000160870(CYP3A7)	--	0.073935774	2	0	0	0	0	0.036487458	1	0	0	0.03671623	1	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17691|0|hsa:1551|CYP3A7, CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA; cytochrome P450, family 3, subfamily A, polypeptide 7 (EC:1.14.14.1); K17691 cytochrome P450, family 3, subfamily A, polypeptide 7 [EC:1.14.14.1] (A)"	Steroid hormone biosynthesis (ko00140);; Retinol metabolism (ko00830);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 3A7 GN=CYP3A7 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	cytochrome p450 3A94 [Equus caballus] 
ENSG00000160877(NACC1)	--	28.913695	2211	30.23699017	2302	29.43273	2322	25.52895001	2069	27.86532932	2188	24.8212078	1943	0.982860837	-0.12650674	normal	0.985257346	-0.094637872	normal	0.950922345	-0.265184443	normal	0.402534623	-0.16195709	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10486|0|pon:100455493|NACC1; nucleus accumbens associated 1, BEN and BTB (POZ) domain containing; K10486 BTB/POZ domain-containing protein 14 (A)"	--	[R]	General function prediction only	BTB/POZ domain;; BEN domain	Nucleus accumbens-associated protein 1 GN=NACC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nucleus accumbens-associated protein 1 [Chrysochloris asiatica]
ENSG00000160883(HK3)	--	0.0168574	1	0	0	0	0	0.0167243	1	0	0	0.0503221	3	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	"Molecular Function: ATP binding (GO:0005524);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K00844|0|hsa:3101|HK3, HKIII, HXK3; hexokinase 3 (white cell) (EC:2.7.1.1); K00844 hexokinase [EC:2.7.1.1] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520);; Butirosin and neomycin biosynthesis (ko00524);; Carbon metabolism (ko01200);; HIF-1 signaling pathway (ko04066);; Insulin signaling pathway (ko04910);; Type II diabetes mellitus (ko04930);; Carbohydrate digestion and absorption (ko04973);; Central carbon metabolism in cancer (ko05230)	[G]	Carbohydrate transport and metabolism	Hexokinase;; Hexokinase	Hexokinase-3 GN=HK3 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: hexokinase-3 [Physeter catodon]
ENSG00000160886(LY6K)	--	1.959361765	75	1.318147323	49	1.418902058	51	0.90423552	39	0.681367606	36	0.617614344	29	0.301785262	-0.946865311	normal	0.953480142	-0.449945064	normal	0.814725399	-0.791231264	normal	0.136907442	-0.773052803	normal	--	--	--	--	--	--	--	--	Lymphocyte antigen 6K (Precursor) GN=LY6K OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: lymphocyte antigen 6K-like [Tupaia chinensis]
ENSG00000160888(IER2)	--	38.69289845	1298	42.73394962	1513	35.05465394	1263	37.261644	1242	33.77859904	1145	29.7292	1044	0.979064905	-0.094343293	normal	0.671222452	-0.423003195	normal	0.921460765	-0.282651526	normal	0.120712638	-0.269750648	normal	--	--	--	--	--	--	--	Immediate early response protein (IER)	Immediate early response gene 2 protein GN=IER2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: immediate early response gene 2 protein [Camelus dromedarius]
ENSG00000160908(ZNF394)	--	7.189024	234	9.731685	315	5.36644	222	6.381381	247	8.45815	309	10.349878	322	0.966190288	0.046870701	normal	0.966037486	-0.048934344	normal	0.455673701	0.525222349	normal	0.647474419	0.166698293	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:84124|ZNF394, ZKSCAN14, ZSCAN46; zinc finger protein 394; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 394 GN=ZNF394 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 394 isoform X1 [Galeopterus variegatus]
ENSG00000160917(CPSF4)	--	21.43021696	637	15.39639391	482	17.0920738	523	20.94020558	621	23.5506312	695	18.83331981	556	0.972186252	-0.067367787	normal	0.372414263	0.505226459	normal	0.969723446	0.079758788	normal	0.50648397	0.167648475	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K14404|0|cjc:103788604|CPSF4; cleavage and polyadenylation specific factor 4, 30kDa; K14404 cleavage and polyadenylation specificity factor subunit 4 (A)"	mRNA surveillance pathway (ko03015);; Influenza A (ko05164)	[A]	RNA processing and modification	Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Zinc knuckle	Cleavage and polyadenylation specificity factor subunit 4 GN=CPSF4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: cleavage and polyadenylation specificity factor subunit 4 isoform 4 [Dasypus novemcinctus]
ENSG00000160932(LY6E)	--	128.0698076	2240	129.9437413	2304	119.221782	2117	100.1903343	1751	117.8700638	2016	107.1417533	1850	0.796752515	-0.385851686	normal	0.969571216	-0.213921395	normal	0.970701684	-0.202632469	normal	0.112464832	-0.267035695	normal	--	--	--	K04393|9.95369e-29|pps:103786242|rho-related protein racA-like; K04393 cell division control protein 42 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; T cell receptor signaling pathway (ko04660);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Regulation of actin cytoskeleton (ko04810);; GnRH signaling pathway (ko04912);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212)	--	--	u-PAR/Ly-6 domain	Lymphocyte antigen 6E (Precursor) GN=LY6E OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: lymphocyte antigen 6E [Galeopterus variegatus]
ENSG00000160948(VPS28)	--	44.9009273	707	46.03334237	693	42.2729159	687	53.29212215	800	54.23017599	825	53.3643928	863	0.965655817	0.147156764	normal	0.942532579	0.22965242	normal	0.873937086	0.320128983	normal	0.244560332	0.232570291	normal	--	--	--	K12184|1.34516e-141|pon:100448574|VPS28; vacuolar protein sorting 28 homolog (S. cerevisiae); K12184 ESCRT-I complex subunit VPS28 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	VPS28 protein	Vacuolar protein sorting-associated protein 28 homolog GN=VPS28 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 28 homolog [Orycteropus afer afer]
ENSG00000160949(TONSL)	--	7.99892235	762	7.539764003	733	9.118908347	901	9.889884426	935	9.000858628	853	9.291037905	890	0.92644703	0.263862153	normal	0.954872747	0.19692907	normal	0.978082561	-0.025969355	normal	0.539907804	0.139507885	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	"K09257|0|hsa:4796|TONSL, IKBR, NFKBIL2; tonsoku-like, DNA repair protein; K09257 NF-kappa-B inhibitor-like protein 2 (A)"	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Tetratricopeptide repeat;; Ankyrin repeats (many copies);; TPR repeat;; Leucine Rich repeat;; Ankyrin repeat;; Tetratricopeptide repeat;; Leucine Rich repeats (2 copies);; Tetratricopeptide repeat	Tonsoku-like protein GN=TONSL OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: tonsoku-like protein [Ceratotherium simum simum]
ENSG00000160951(PTGER1)	--	0.702598	10	0.0662395	1	0.192882	2	0	0	0	0	0.413119	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04258|1.71606e-115|hsa:5731|PTGER1, EP1; prostaglandin E receptor 1 (subtype EP1), 42kDa; K04258 prostaglandin E receptor 1 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Prostaglandin E2 receptor EP1 subtype GN=PTGER1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: prostaglandin E2 receptor EP1 subtype [Orcinus orca]
ENSG00000160953(MUM1)	--	11.62642757	859	10.31121924	783	11.65479236	899	9.421710661	709	9.198970335	657	8.136064917	565	0.888513638	-0.307099035	normal	0.917159018	-0.273966986	normal	0.015329055	-0.676912126	normal	0.015588288	-0.417717398	normal	--	--	--	--	--	--	--	PWWP domain	PWWP domain-containing protein MUM1 GN=MUM1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: PWWP domain-containing protein MUM1 isoform X3 [Galeopterus variegatus]
ENSG00000160957(RECQL4)	--	15.92946522	1219	15.00937361	1135	15.03250274	1192	17.26004265	1307	14.16869559	1106	14.18093384	1068	0.980506306	0.069643973	normal	0.979181759	-0.058688251	normal	0.968523006	-0.166540689	normal	0.861812408	-0.048502138	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K10730|0|hsa:9401|RECQL4, RECQ4; RecQ protein-like 4 (EC:3.6.4.12); K10730 ATP-dependent DNA helicase Q4 [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; DNA replication and checkpoint protein	ATP-dependent DNA helicase Q4 GN=RECQL4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ATP-dependent DNA helicase Q4 [Galeopterus variegatus]
ENSG00000160959(LRRC14)	--	15.74647	740	14.40005	715	16.23158	739	19.728512	896	16.93375	852	16.63618	813	0.936716512	0.244678977	normal	0.942533537	0.231035512	normal	0.96896845	0.12913751	normal	0.329392599	0.201695905	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine Rich repeats (2 copies)	Leucine-rich repeat-containing protein 14 GN=LRRC14 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 14 isoform X1 [Tupaia chinensis] 
ENSG00000160961(ZNF333)	--	1.0398344	73	0.560527	40	1.3513583	92	0.8779871	60	0.8186964	51	1.3083375	66	0.957997708	-0.306634371	normal	0.967222465	0.318388853	normal	0.888193798	-0.478137373	normal	0.742525931	-0.231818176	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100971043|ZNF333; zinc finger protein 333; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 333 GN=ZNF333 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	"PREDICTED: zinc finger protein 333, partial [Galeopterus variegatus]"
ENSG00000160963(COL26A1)	--	0.529721336	32	0.402004	26	0.692004	45	0.28474586	18	0.588527	37	0.17128	11	0.926538893	-0.808474675	normal	0.966392683	0.464825734	normal	0.006016585	-1.901921896	down	0.405511365	-0.662883318	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	EMI domain;; Collagen triple helix repeat (20 copies)	Collagen alpha-1(XXVI) chain (Precursor) GN=COL26A1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: collagen alpha-1(XXVI) chain [Ceratotherium simum simum]
ENSG00000160972(PPP1R16A)	--	20.825731	1194	20.54425342	1205	20.1654898	1183	22.13410594	1268	19.52913739	1115	18.10047562	1044	0.980828331	0.055849904	normal	0.973681263	-0.133242099	normal	0.963540817	-0.188363299	normal	0.72414429	-0.085647532	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17458|0|hsa:84988|PPP1R16A, MYPT3; protein phosphatase 1, regulatory subunit 16A; K17458 protein phosphatase 1 regulatory subunit 16A (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Protein phosphatase 1 regulatory subunit 16A (Precursor) GN=PPP1R16A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 16A [Galeopterus variegatus]
ENSG00000160973(FOXH1)	--	3.4803	155	3.95996	177	3.16107	143	3.69543	164	2.41249	107	3.39212	153	0.966805514	0.050112409	normal	0.153759773	-0.739351453	normal	0.96542963	0.088321923	normal	0.675100826	-0.185756144	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09400|0|hsa:8928|FOXH1, FAST-1, FAST1; forkhead box H1; K09400 forkhead box protein H (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein H1 GN=FOXH1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein H1 [Galeopterus variegatus]
ENSG00000160991(ORAI2)	--	29.76788196	1645	27.9289327	1715	31.0074952	1654	36.2840343	1876	35.1226165	1956	32.93178888	1653	0.97668897	0.1586012	normal	0.975690047	0.168132336	normal	0.985045165	-0.009155578	normal	0.621092743	0.107987839	normal	--	--	--	K16057|6.00328e-178|pps:100988709|ORAI2; ORAI calcium release-activated calcium modulator 2; K16057 calcium release-activated calcium channel protein 2 (A)	Calcium signaling pathway (ko04020)	[A]	RNA processing and modification	Mediator of CRAC channel activity	Protein orai-2 GN=ORAI2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: protein orai-2 [Ailuropoda melanoleuca] 
ENSG00000160993(ALKBH4)	--	5.56128	220	4.9058	198	5.35551	217	5.5802	222	6.21247	244	4.72234	188	0.966861036	-0.017653382	normal	0.919409624	0.278038263	normal	0.945414611	-0.213652683	normal	0.972589608	0.021051367	normal	--	--	--	"K10766|0|hsa:54784|ALKBH4, ABH4; alkB, alkylation repair homolog 4 (E. coli); K10766 alkylated DNA repair protein alkB homolog 4 [EC:1.14.11.-] (A)"	--	[R]	General function prediction only	2OG-Fe(II) oxygenase superfamily	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 GN=ALKBH4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 [Galeopterus variegatus]
ENSG00000160999(SH2B2)	--	5.014618761	160	3.541366241	118	4.178138804	155	5.649141797	150	2.567691929	92	3.464207057	109	0.962638288	-0.1227242	normal	0.911051195	-0.37504884	normal	0.739692504	-0.510263787	normal	0.42041232	-0.325051862	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K07193|0|hsa:10603|SH2B2, APS; SH2B adaptor protein 2; K07193 SH2B adapter protein 2 (A)"	Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910)	--	--	Phenylalanine zipper;; SH2 domain;; PH domain	SH2B adapter protein 2 GN=SH2B2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SH2B adapter protein 2 [Orcinus orca]
ENSG00000161010(MRNIP)	--	129.786086	4444	180.0759	6262	141.02976	4954	121.0040492	4025	92.858708	3102	160.08744	5501	0.98609019	-0.173639181	normal	8.79E-08	-1.034488773	down	0.990284312	0.142767217	normal	0.455402567	-0.330977729	normal	--	--	--	--	--	--	--	--	UPF0544 protein C5orf45 GN=C5orf45 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: UPF0544 protein C5orf45-like [Galeopterus variegatus]
ENSG00000161011(SQSTM1)	--	722.042989	20090	798.3701056	27804	948.84841	22628	682.2336	16854	489.788581	14165	876.000088	24122	0.987578766	-0.28419503	normal	8.06E-07	-0.99431113	normal	0.997853193	0.083943576	normal	0.349100212	-0.375265169	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	K14381|0|ptr:462333|SQSTM1; sequestosome 1; K14381 sequestosome 1 (A)	Osteoclast differentiation (ko04380)	--	--	"Zinc finger, ZZ type;; PB1 domain"	Sequestosome-1 GN=SQSTM1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sequestosome-1 [Camelus bactrianus]
ENSG00000161013(MGAT4B)	--	88.8390349	3972	96.925372	4424	91.720151	4229	117.705108	5234	102.0934745	4665	120.5230829	5459	0.895647899	0.367092008	normal	0.992212433	0.055080801	normal	0.908240133	0.359915119	normal	0.134591224	0.261581073	normal	--	--	"Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00738|0|pps:100981022|MGAT4B; mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B; K00738 alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase A/B [EC:2.4.1.145] (A)"	N-Glycan biosynthesis (ko00510)	--	--	N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region	"Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B GN=MGAT4B OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B, partial [Eptesicus fuscus]"
ENSG00000161016(RPL8)	--	1554.283463	23596	1400.06202	22153	1461.618631	23179	1711.542601	26994	1706.109543	25975	1461.607448	22406	0.996984638	0.163254251	normal	0.995381321	0.208181971	normal	0.997977809	-0.057220854	normal	0.691082661	0.107315471	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02938|5.60444e-177|lve:103074728|RPL8; ribosomal protein L8; K02938 large subunit ribosomal protein L8e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal Proteins L2, C-terminal domain;; Ribosomal Proteins L2, RNA binding domain"	60S ribosomal protein L8 GN=RPL8 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L8 [Lipotes vexillifer]
ENSG00000161021(MAML1)	--	8.18382	938	9.40301	1077	8.24127	948	9.48372	1075	11.248	1284	10.5303	1211	0.96668728	0.165591072	normal	0.950855315	0.231901853	normal	0.848142758	0.344461123	normal	0.170322516	0.247951652	normal	--	--	Molecular Function: transcription coactivator activity (GO:0003713);; Biological Process: Notch signaling pathway (GO:0007219);; Cellular Component: nuclear speck (GO:0016607);; Biological Process: positive regulation of transcription from RNA polymerase II promoter (GO:0045944);; 	"K06061|0|hsa:9794|MAML1, Mam-1, Mam1; mastermind-like 1 (Drosophila); K06061 mastermind (A)"	Notch signaling pathway (ko04330)	--	--	MamL-1 domain	Mastermind-like protein 1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: mastermind-like protein 1 [Sus scrofa]
ENSG00000161036(LRWD1)	--	15.90473753	640	14.3635832	609	17.69261622	740	14.17268343	548	14.74151503	590	13.3098347	549	0.926354681	-0.254068292	normal	0.971056098	-0.066984825	normal	0.601541776	-0.437967432	normal	0.213383495	-0.258404094	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Leucine Rich repeats (2 copies);; Leucine rich repeat;; WD domain, G-beta repeat;; Leucine Rich Repeat"	Leucine-rich repeat and WD repeat-containing protein 1 GN=LRWD1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leucine-rich repeat and WD repeat-containing protein 1 [Trichechus manatus latirostris]
ENSG00000161040(FBXL13)	--	0.5141303	14	0.183235	8	0.2471977	8	0.3205507	14	0.2528633	10	0.119079	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K10279|0|nle:100598241|FBXL13; F-box and leucine-rich repeat protein 13; K10279 F-box and leucine-rich repeat protein 13 (A)	--	[R]	General function prediction only	Leucine Rich repeat;; Leucine Rich Repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine rich repeat	F-box/LRR-repeat protein 13 GN=FBXL13 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 13 [Ursus maritimus]
ENSG00000161048(NAPEPLD)	--	5.124652	398	5.057570674	392	5.308091	411	6.613745005	523	6.162149	458	6.517029	498	0.813446327	0.361988051	normal	0.945196221	0.202344625	normal	0.916488574	0.267819381	normal	0.222832775	0.279068044	normal	[R]	General function prediction only	--	"K13985|0|hsa:222236|NAPEPLD, FMP30, NAPE-PLD; N-acyl phosphatidylethanolamine phospholipase D (EC:3.1.4.54); K13985 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D [EC:3.1.4.54] (A)"	Retrograde endocannabinoid signaling (ko04723)	[R]	General function prediction only	Beta-lactamase superfamily domain;; Beta-lactamase superfamily domain	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D GN=NAPEPLD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	N-acyl-phosphatidylethanolamine-hydrolyzing phospholipase D [Tupaia chinensis]
ENSG00000161057(PSMC2)	--	66.71454467	1932	76.98935308	2127	75.63677649	1987	80.4463112	2286	77.67486329	2276	69.39866106	1969	0.96959908	0.211743107	normal	0.985922292	0.076201586	normal	0.986668437	-0.021403839	normal	0.692157708	0.089669279	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K03061|0|umr:103658639|PSMC2; proteasome (prosome, macropain) 26S subunit, ATPase, 2; K03061 26S proteasome regulatory subunit T1 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily)	26S protease regulatory subunit 7 GN=PSMC2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: 26S protease regulatory subunit 7 [Lipotes vexillifer]
ENSG00000161082(CELF5)	--	0.998776	72	0.731614195	51	0.72534702	55	0.406019515	30	0.367601296	21	0.236179907	14	0.034333013	-1.251197756	normal	0.199478029	-1.242340804	normal	0.001261889	-1.872929456	down	0.00209908	-1.476953111	down	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13207|0|cfa:612072|CELF5, BRUNOL5; CUGBP, Elav-like family member 5; K13207 CUG-BP- and ETR3-like factor (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	CUGBP Elav-like family member 5 GN=CELF5 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: CUGBP Elav-like family member 5 isoform 1 [Odobenus rosmarus divergens]
ENSG00000161091(MFSD12)-2	--	46.332603	1410	56.61936	1856	49.07293153	1524	47.1087454	1495	50.18486259	1465	62.01398152	1871	0.982790951	0.053561376	normal	0.84282364	-0.362389383	normal	0.930351074	0.287397401	normal	0.985893701	-0.00842324	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000161091(MFSD12)-3	--	10.878	86	14.4218	118	13.2388	111	16.4938	142	17.7116	140	19.6183	165	0.401130899	0.683064518	normal	0.950096942	0.22259186	normal	0.625679584	0.557348004	normal	0.181333013	0.484254368	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000161179(YDJC)	--	30.479269	558	24.35656	460	27.01319	522	35.84016	669	34.02052	622	32.99505	610	0.938784678	0.230329021	normal	0.701276189	0.412683461	normal	0.943919033	0.215888874	normal	0.173404601	0.282430733	normal	[S]	Function unknown	--	--	--	--	--	YdjC-like protein	UPF0249 protein ydjC homolog GN=YDJC OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: UPF0249 protein ydjC homolog [Equus przewalskii]
ENSG00000161180(CCDC116)	--	0	0	0.06536618	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 116 GN=CCDC116 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 116 [Galeopterus variegatus]
ENSG00000161202(DVL3)	--	11.12953876	1100	11.50803421	1113	12.08810339	1154	12.45783292	1186	13.73933774	1351	12.50497199	1243	0.978856566	0.077663742	normal	0.939972694	0.257829135	normal	0.978046827	0.098766895	normal	0.487501218	0.146003387	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K02353|0|lve:103082466|DVL3; dishevelled segment polarity protein 3; K02353 segment polarity protein dishevelled (A)	Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[R]	General function prediction only	"Segment polarity protein dishevelled (Dsh) C terminal;; DIX domain;; Dishevelled specific domain;; PDZ domain (Also known as DHR or GLGF);; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	Segment polarity protein dishevelled homolog DVL-3 GN=DVL3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: segment polarity protein dishevelled homolog DVL-3 [Camelus bactrianus]
ENSG00000161203(AP2M1)	--	111.693247	4522	99.80043803	4092	120.1803446	4920	152.961791	6217	150.76797	6027	120.51673	4928	0.776398537	0.42830076	normal	0.306823729	0.53704288	normal	0.993324908	-0.005945676	normal	0.052378373	0.321899709	normal	--	--	--	"K11826|0|phd:102321207|AP2M1; adaptor-related protein complex 2, mu 1 subunit; K11826 AP-2 complex subunit mu-1 (A)"	Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family;; Clathrin adaptor complex small chain	AP-2 complex subunit mu GN=AP2M1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	AP-2 complex subunit mu-1 [Bos mutus]
ENSG00000161204(ABCF3)	--	12.15385676	661	10.28385314	573	12.20502316	679	11.43552794	625	12.756085	688	10.118945	550	0.96863841	-0.11136009	normal	0.933838128	0.24186365	normal	0.880902068	-0.311499044	normal	0.844956503	-0.059479294	normal	[R]	General function prediction only	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K06158|0|hsa:55324|ABCF3, EST201864; ATP-binding cassette, sub-family F (GCN20), member 3; K06158 ATP-binding cassette, subfamily F, member 3 (A)"	--	[EJ]	"Amino acid transport and metabolism;; Translation, ribosomal structure and biogenesis"	ABC transporter;; ABC transporter;; AAA domain;; RecF/RecN/SMC N terminal domain;; AAA domain;; AAA ATPase domain;; AAA domain;; NACHT domain;; Miro-like protein	ATP-binding cassette sub-family F member 3 GN=ABCF3 OS=Homo sapiens (Human) PE=1 SV=2	EJ	"Amino acid transport and metabolism;; Translation, ribosomal structure and biogenesis"	PREDICTED: ATP-binding cassette sub-family F member 3 [Capra hircus] 
ENSG00000161217(PCYT1A)	--	14.52825664	1051	12.21828179	1002	12.42962345	1050	20.86884862	1575	17.331915	1372	17.91958021	1379	0.150933119	0.552093581	normal	0.636641296	0.431412916	normal	0.770293322	0.384457081	normal	0.002611218	0.457784378	normal	[MI]	Cell wall/membrane/envelope biogenesis;; Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: biosynthetic process (GO:0009058);; 	"K00968|0|bta:100125779|PCYT1A; phosphate cytidylyltransferase 1, choline, alpha (EC:2.7.7.15); K00968 choline-phosphate cytidylyltransferase [EC:2.7.7.15] (A)"	Glycerophospholipid metabolism (ko00564);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Cytidylyltransferase	Choline-phosphate cytidylyltransferase A GN=PCYT1A OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	choline-phosphate cytidylyltransferase A [Bos taurus] 
ENSG00000161243(FBXO27)	--	30.6899894	823	26.22068198	721	21.31385911	854	2.843460629	114	4.885855449	80	3.576501539	142	0	-2.865833425	down	0	-3.169138012	down	0	-2.583854729	down	1.11E-57	-2.855722226	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	F-box associated region;; F-box domain;; F-box-like	F-box only protein 27 GN=FBXO27 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box only protein 27 [Canis lupus familiaris]
ENSG00000161249(DMKN)	--	17.28467001	130	16.12238197	106	15.47213669	129	40.29681816	301	32.69872267	259	33.37245737	268	6.55E-06	1.171072251	up	3.66E-06	1.255636178	up	0.000231887	1.037945261	up	1.91E-06	1.160341575	up	--	--	--	--	--	--	--	--	Dermokine (Precursor) GN=DMKN OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: uncharacterized protein LOC101377294 [Odobenus rosmarus divergens]
ENSG00000161265(U2AF1L4)	--	7.831584724	89	7.107183023	85	8.150139739	98	7.346841673	87	4.96932133	57	7.115301	84	0.971589873	-0.062530326	normal	0.818081549	-0.585127828	normal	0.959263465	-0.226898057	normal	0.604960598	-0.275838279	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: metal ion binding (GO:0046872);; 	K12836|1.47278e-142|ocu:100347194|U2AF1L4; U2 small nuclear RNA auxiliary factor 1-like 4; K12836 splicing factor U2AF 35 kDa subunit (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"Zinc finger C-x8-C-x5-C-x3-H type (and similar);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing factor U2AF 26 kDa subunit GN=U2AF1L4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: splicing factor U2AF 26 kDa subunit isoform X2 [Galeopterus variegatus]
ENSG00000161267(BDH1)	--	2.093352917	68	2.143773052	66	2.929019458	92	4.84437859	155	4.420216447	141	3.275249409	94	0.001184603	1.140316669	up	0.007306697	1.056791394	up	0.971455276	0.022371641	normal	0.034911146	0.765195148	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00019|0|hsa:622|BDH1, BDH, SDR9C1; 3-hydroxybutyrate dehydrogenase, type 1 (EC:1.1.1.30); K00019 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] (A)"	Synthesis and degradation of ketone bodies (ko00072);; Butanoate metabolism (ko00650)	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; Fungal family of unknown function (DUF1776)	"D-beta-hydroxybutyrate dehydrogenase, mitochondrial (Precursor) GN=BDH1 OS=Homo sapiens (Human) PE=1 SV=3"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: D-beta-hydroxybutyrate dehydrogenase, mitochondrial-like isoform X1 [Tupaia chinensis] "
ENSG00000161270(NPHS1)	--	0.810867323	56	0.872295076	54	0.50975853	40	0.225410514	19	0.492136068	34	1.177982696	96	0.018248918	-1.515555701	normal	0.875877803	-0.665167345	normal	0.008479002	1.223969456	up	0.992194587	-0.026868535	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Fibronectin type III domain;; Immunoglobulin C1-set domain	Nephrin (Precursor) GN=NPHS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: nephrin [Vicugna pacos]
ENSG00000161281(COX7A1)	--	0.548934	6	0	0	0.343013	3	0.171674	2	0.351903	3	0.529327	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K02270|9.00543e-52|hsa:1346|COX7A1, COX7A, COX7AH, COX7AM; cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) (EC:1.9.3.1); K02270 cytochrome c oxidase subunit 7a (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	Cytochrome c oxidase subunit VIIa	"Cytochrome c oxidase subunit 7A1, mitochondrial (Precursor) GN=COX7A1 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: cytochrome c oxidase subunit 7A1, mitochondrial-like [Physeter catodon]"
ENSG00000161298(ZNF382)	--	0.031627603	4	0	0	0	0	0.186866	4	0	0	0.0611806	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101146060|ZNF382; zinc finger protein 382 isoform 1; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Transposase zinc-ribbon domain"	Zinc finger protein 382 GN=ZNF382 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 382 isoform 1 [Ceratotherium simum simum]
ENSG00000161328(LRRC56)	--	0.368806	21	0.563687	33	0.267022	15	0.4217	24	0.256213	14	0.744651	43	0.987373504	0.151443816	normal	0.699607946	-1.173611524	normal	0.168905551	1.422892725	normal	0.883429944	0.210887764	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 56 GN=LRRC56 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 56 [Ceratotherium simum simum]
ENSG00000161381(PLXDC1)	--	0.326522683	23	0.017907598	2	0.941571104	14	0.175346265	2	0.212108105	11	0.216215392	9	0.018175146	-2.817726917	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Plexin repeat	Plexin domain-containing protein 1 (Precursor) GN=PLXDC1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: plexin domain-containing protein 1 [Canis lupus familiaris]
ENSG00000161395(PGAP3)	--	7.293244314	304	6.656102	311	5.653380006	274	6.2616494	277	6.823467	310	6.142042	273	0.954204804	-0.164148059	normal	0.96676331	-0.025946552	normal	0.967404604	-0.013491783	normal	0.86274829	-0.069220454	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Per1-like	Post-GPI attachment to proteins factor 3 (Precursor) GN=PGAP3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: post-GPI attachment to proteins factor 3 isoform 1 [Equus caballus]
ENSG00000161509(GRIN2C)	--	0.6783029	50	0.5398986	40	0.4758573	34	0.3473933	24	0.28802099	21	0.30635108	23	0.513532082	-1.042479706	normal	0.81938132	-0.90314244	normal	0.964235153	-0.542672289	normal	0.129255448	-0.888533172	normal	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05211|0|hsa:2905|GRIN2C, GluN2C, NMDAR2C, NR2C; glutamate receptor, ionotropic, N-methyl D-aspartate 2C; K05211 glutamate receptor ionotropic, NMDA 2C (A)"	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033);; Alcoholism (ko05034)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site;; Receptor family ligand binding region;; N-methyl D-aspartate receptor 2B3 C-terminus"	"Glutamate receptor ionotropic, NMDA 2C (Precursor) GN=GRIN2C OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, NMDA 2C [Ceratotherium simum simum]"
ENSG00000161513(FDXR)	--	53.34156728	1918	55.81480194	2098	53.97462305	2039	36.16049588	1331	32.990189	1176	48.891335	1779	0.135864306	-0.557385098	normal	7.52E-05	-0.855717198	normal	0.969461227	-0.204923855	normal	0.008296939	-0.518845028	normal	[ER]	Amino acid transport and metabolism;; General function prediction only	--	"K18914|0|hsa:2232|FDXR, ADXR; ferredoxin reductase (EC:1.18.1.6); K18914 adrenodoxin-NADP+ reductase [EC:1.18.1.6] (A)"	--	[F]	Nucleotide transport and metabolism	--	"NADPH:adrenodoxin oxidoreductase, mitochondrial (Precursor) GN=FDXR OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: NADPH:adrenodoxin oxidoreductase, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000161526(SAP30BP)	--	19.047681	1123	19.174962	1141	20.979887	1243	22.810325	1342	23.738713	1377	20.601544	1178	0.953897981	0.22591146	normal	0.944743487	0.249501821	normal	0.979129512	-0.085671116	normal	0.542009465	0.130767663	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	HCNGP-like protein	SAP30-binding protein OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: SAP30-binding protein [Ochotona princeps]
ENSG00000161533(ACOX1)	--	12.946265	1031	12.63088	1078	15.0904	1110	13.4316717	1205	13.44430016	1263	12.65292	1110	0.962045136	0.19388909	normal	0.959263375	0.206802653	normal	0.980783653	-0.008280161	normal	0.544435609	0.131240245	normal	[I]	Lipid transport and metabolism	"Molecular Function: acyl-CoA oxidase activity (GO:0003997);; Cellular Component: peroxisome (GO:0005777);; Biological Process: fatty acid beta-oxidation (GO:0006635);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00232|0|pps:100984758|ACOX1; acyl-CoA oxidase 1, palmitoyl; K00232 acyl-CoA oxidase [EC:1.3.3.6] (A)"	Fatty acid degradation (ko00071);; alpha-Linolenic acid metabolism (ko00592);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; cAMP signaling pathway (ko04024);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	"Acyl-CoA oxidase;; Acyl-coenzyme A oxidase N-terminal;; Acyl-CoA dehydrogenase, middle domain"	Peroxisomal acyl-coenzyme A oxidase 1 GN=ACOX1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: peroxisomal acyl-coenzyme A oxidase 1 isoform X2 [Tupaia chinensis]
ENSG00000161542(PRPSAP1)	--	23.7639926	969	18.55475994	807	23.653633	899	20.8461332	862	20.3415473	792	18.4779197	778	0.956883753	-0.199305746	normal	0.975472779	-0.048403238	normal	0.949782119	-0.216450634	normal	0.468744001	-0.158853858	normal	[FE]	Nucleotide transport and metabolism;; Amino acid transport and metabolism	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: ribose phosphate diphosphokinase activity (GO:0004749);; Biological Process: nucleoside metabolic process (GO:0009116);; Biological Process: nucleotide biosynthetic process (GO:0009165);; 	--	--	[EF]	Amino acid transport and metabolism;; Nucleotide transport and metabolism	Phosphoribosyl synthetase-associated domain;; N-terminal domain of ribose phosphate pyrophosphokinase	Phosphoribosyl pyrophosphate synthase-associated protein 1 GN=PRPSAP1 OS=Homo sapiens (Human) PE=1 SV=2	EF	Amino acid transport and metabolism;; Nucleotide transport and metabolism	PREDICTED: phosphoribosyl pyrophosphate synthase-associated protein 1 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000161544(CYGB)	--	2.075114221	109	3.742923	130	2.423998795	121	3.332180455	119	4.986738035	164	3.3029838	135	0.967528709	0.094525784	normal	0.91972732	0.310535241	normal	0.962176572	0.147910019	normal	0.678807371	0.194790064	normal	--	--	Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; 	--	--	[C]	Energy production and conversion	Globin	Cytoglobin GN=CYGB OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: cytoglobin [Loxodonta africana]
ENSG00000161547(SRSF2)	--	123.5049185	3631	120.37865	3446	117.77514	3350	132.443525	3811	153.0854614	4462	84.90630163	2566	0.991456034	0.038954325	normal	0.91125543	0.351205475	normal	0.812830007	-0.392728172	normal	0.952709638	0.033759334	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12891|1.73337e-53|oaa:100084322|SRSF2; serine/arginine-rich splicing factor 2; K12891 splicing factor, arginine/serine-rich 2 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Serine/arginine-rich splicing factor 2 GN=SRSF2 OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 2 [Ornithorhynchus anatinus] 
ENSG00000161551(ZNF577)	--	0.716963239	71	1.032819803	85	1.96403139	89	0.49101116	33	0.632064147	36	0.559851338	45	0.129621743	-1.100405729	normal	0.016579748	-1.226349203	normal	0.152745727	-0.968589135	normal	0.007998792	-1.123802096	down	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:748901|ZNF577; zinc finger protein 577; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 577 GN=ZNF577 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 577 isoform X1 [Equus caballus]
ENSG00000161558(TMEM143)	--	5.780231038	236	4.1464232	173	4.62455144	202	2.406102346	104	2.749192341	114	4.399929034	183	1.62E-05	-1.200915457	down	0.44873331	-0.616475753	normal	0.957999891	-0.149625664	normal	0.079225387	-0.627016708	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3754)	Transmembrane protein 143 GN=TMEM143 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 143 isoform X1 [Tupaia chinensis] 
ENSG00000161594(KLHL10)	--	0.1760663	3	0.027010879	1	0.256855612	5	0.0274093	1	0.1207382	1	0.137250019	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10448|0|hsa:317719|KLHL10, SPGF11; kelch-like family member 10; K10448 kelch-like protein 10 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 10 GN=KLHL10 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 10 isoformX1 [Equus caballus] 
ENSG00000161609(CCDC155)	--	0.01893213	1	0	0	0	0	0	0	0	0	0.09634489	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil region of CCDC155;; EF-hand domain	Protein KASH5 GN=CCDC155 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein KASH5 [Galeopterus variegatus]
ENSG00000161618(ALDH16A1)	--	11.030102	594	10.76810507	626	11.355615	643	12.024355	647	11.08694512	595	11.224556	604	0.970141318	0.092241874	normal	0.969178408	-0.094465432	normal	0.969763	-0.098322987	normal	0.916784659	-0.034563615	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[C]	Energy production and conversion	Aldehyde dehydrogenase family;; Protein of unknown function (DUF1487)	Aldehyde dehydrogenase family 16 member A1 GN=ALDH16A1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: aldehyde dehydrogenase family 16 member A1 isoform X1 [Eptesicus fuscus]
ENSG00000161638(ITGA5)	--	25.221842	2455	19.01012465	1870	22.03769423	2144	38.90382	3511	37.16548	3529	26.2205255	2575	0.457995395	0.485071667	normal	1.78E-05	0.894259705	normal	0.957883956	0.255811223	normal	0.02104216	0.549784055	normal	--	--	--	"K06484|0|hsa:3678|ITGA5, CD49e, FNRA, VLA-5, VLA5A; integrin, alpha 5 (fibronectin receptor, alpha polypeptide); K06484 integrin alpha 5 (A)"	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Hematopoietic cell lineage (ko04640);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Shigellosis (ko05131);; Pertussis (ko05133);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Integrin alpha-5 light chain (Precursor) GN=ITGA5 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin alpha-5 [Equus caballus]
ENSG00000161642(ZNF385A)	--	9.796159579	433	6.90427397	296	8.077109928	360	8.967395	397	8.792884887	378	8.544492225	387	0.957307586	-0.155483836	normal	0.869155383	0.329867928	normal	0.964999603	0.095657581	normal	0.837914133	0.072381696	normal	--	--	--	--	--	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; U1 zinc finger	Zinc finger protein 385A GN=ZNF385A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 385A isoform X1 [Orycteropus afer afer]
ENSG00000161647(MPP3)	--	4.997916538	431	4.491996275	398	4.93515232	419	3.697256651	316	4.59611616	352	3.207394238	267	0.534655616	-0.476602382	normal	0.945848152	-0.197819689	normal	0.069415606	-0.655413029	normal	0.04726856	-0.438112051	normal	[F]	Nucleotide transport and metabolism	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Guanylate kinase;; L27 domain;; PDZ domain (Also known as DHR or GLGF);; Variant SH3 domain	MAGUK p55 subfamily member 3 GN=MPP3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: MAGUK p55 subfamily member 3 isoform X1 [Tupaia chinensis] 
ENSG00000161649(CD300LG)	--	0.0353907	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16663|3.4687e-173|ggo:101125916|CD300LG; CMRF35-like molecule 9 isoform 1; K16663 CMRF35-like molecule 9 (A)	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain	CMRF35-like molecule 9 (Precursor) GN=CD300LG OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: CMRF35-like molecule 9 isoform X2 [Ailuropoda melanoleuca]
ENSG00000161653(NAGS)	--	0.930569634	22	0.680787233	18	0.82224235	19	1.002830468	25	1.059710125	23	0.466742186	12	0.986984625	0.144145161	normal	0.984843295	0.30918695	normal	--	--	--	1	0.001139341	normal	[E]	Amino acid transport and metabolism	--	K11067|0|ptr:468274|NAGS; N-acetylglutamate synthase; K11067 N-acetylglutamate synthase [EC:2.3.1.1] (A)	Arginine and proline metabolism (ko00330);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Protein of unknown function (DUF619)	N-acetylglutamate synthase conserved domain form (Precursor) GN=NAGS OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	"PREDICTED: N-acetylglutamate synthase, mitochondrial [Condylura cristata]"
ENSG00000161654(LSM12)	--	43.76765879	1501	48.56270794	1583	45.49091996	1479	45.72244041	1550	47.50706612	1596	38.81049788	1334	0.984146421	0.015496366	normal	0.98423945	-0.009618011	normal	0.973630242	-0.156985727	normal	0.858121989	-0.048144617	normal	--	--	--	--	--	[S]	Function unknown	Anticodon-binding domain	Protein LSM12 homolog GN=LSM12 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein LSM12 homolog [Mustela putorius furo]
ENSG00000161664(ASB16)	--	1.46039455	50	1.62656659	58	1.49016146	53	1.56545721	54	0.898045482	31	1.38546751	48	0.978037536	0.077895563	normal	0.611599451	-0.892858525	normal	0.976364315	-0.146844661	normal	0.659346557	-0.297521841	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10338|0|hsa:92591|ASB16; ankyrin repeat and SOCS box containing 16; K10338 ankyrin repeat and SOCS box protein 16 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SOCS box	Ankyrin repeat and SOCS box protein 16 GN=ASB16 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 16 isoform X1 [Bubalus bubalis]
ENSG00000161671(EMC10)	--	81.84306395	2908	85.23710578	3165	83.42776335	3025	106.8840084	3844	103.2635389	3663	116.524718	4231	0.867209174	0.37157758	normal	0.9815157	0.189309504	normal	0.529923512	0.475570159	normal	0.029331042	0.346610693	normal	--	--	--	--	--	[S]	Function unknown	--	ER membrane protein complex subunit 10 (Precursor) GN=EMC10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ER membrane protein complex subunit 10 [Bubalus bubalis]
ENSG00000161677(JOSD2)	--	43.62779	538	40.838929	529	48.733916	637	46.5127	598	50.10413	601	53.37651	658	0.965897155	0.121378175	normal	0.958446852	0.162235367	normal	0.973977948	0.038413039	normal	0.708013448	0.103467813	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Biological Process: protein deubiquitination (GO:0016579);; 	K15235|3.19423e-104|pps:100991032|JOSD2; Josephin domain containing 2; K15235 josephin [EC:3.4.19.12] (A)	--	[R]	General function prediction only	Josephin	Josephin-2 GN=JOSD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: josephin-2 isoform 1 [Ceratotherium simum simum] 
ENSG00000161681(SHANK1)	--	0.12097337	16	0.069667448	9	0.059537163	7	0.011474555	1	0.0546939	5	0.033350285	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K15009|0|lve:103082870|SHANK1; SH3 and multiple ankyrin repeat domains 1; K15009 SH3 and multiple ankyrin repeat domains protein (A)	Glutamatergic synapse (ko04724)	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; Ankyrin repeats (many copies);; Variant SH3 domain;; Ankyrin repeat;; SAM domain (Sterile alpha motif);; Variant SH3 domain;; PDZ domain (Also known as DHR or GLGF);; SH3 domain	SH3 and multiple ankyrin repeat domains protein 1 GN=SHANK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: SH3 and multiple ankyrin repeat domains protein 1 [Lipotes vexillifer]
ENSG00000161682(FAM171A2)	--	11.4304068	571	7.308555106	380	8.574078	457	7.461171042	377	11.123342	558	5.712581	291	0.068436045	-0.627663601	normal	0.312884377	0.531085153	normal	0.058587428	-0.656719501	normal	0.711841216	-0.221228304	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0560	Protein FAM171A2 (Precursor) GN=FAM171A2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM171A2 isoform X1 [Bos taurus]
ENSG00000161692(DBF4B)	--	7.144769571	850	8.501749216	963	9.18668401	1007	7.231245595	764	6.901828	781	7.4853147	855	0.958859675	-0.184370717	normal	0.875274619	-0.323075267	normal	0.940056387	-0.243960719	normal	0.176543626	-0.253349413	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[LD]	"Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	DBF zinc finger	Protein DBF4 homolog B GN=DBF4B OS=Homo sapiens (Human) PE=1 SV=1	DL	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: DBF4 zinc finger B [Lipotes vexillifer]
ENSG00000161714(PLCD3)	--	28.435418	2923	24.76671	2662	27.236949	3183	51.1616368	4864	43.302919	4458	44.764864	4519	0.004901504	0.703571606	normal	0.003767558	0.72213916	normal	0.431452125	0.49712575	normal	7.15E-06	0.637448089	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05857|0|hsa:113026|PLCD3, PLC-delta-3; phospholipase C, delta 3 (EC:3.1.4.11); K05857 phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070);; Thyroid hormone signaling pathway (ko04919)	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; EF hand;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain;; EF-hand domain pair"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 GN=PLCD3 OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 [Orycteropus afer afer]"
ENSG00000161791(FMNL3)	--	1.328253306	301	1.564614302	323	1.9241119	335	1.060128209	207	0.9307359	211	0.57596604	152	0.337521934	-0.567449728	normal	0.159599146	-0.632027236	normal	5.72E-06	-1.140537013	down	0.000666163	-0.772441347	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain	Formin-like protein 3 GN=FMNL3 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: formin-like protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000161798(AQP5)	--	0	0	0.222611	5	0.260835	5	0	0	0	0	0.0451466	1	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K09867|6.03129e-161|hsa:362|AQP5, AQP-5, PPKB; aquaporin 5; K09867 aquaporin-5 (A)"	Salivary secretion (ko04970)	[G]	Carbohydrate transport and metabolism	Major intrinsic protein	Aquaporin-5 GN=AQP5 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-5 [Galeopterus variegatus]
ENSG00000161800(RACGAP1)	--	40.27562398	2158	42.19579457	2203	38.65340362	2169	45.11097599	2364	38.76458919	2073	39.41978762	2046	0.985292535	0.100634439	normal	0.983868481	-0.109098715	normal	0.98504757	-0.092448972	normal	0.908582904	-0.032099896	normal	--	--	Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K16733|0|hsa:29127|RACGAP1, CYK4, HsCYK-4, ID-GAP, MgcRacGAP; Rac GTPase activating protein 1; K16733 Rac GTPase-activating protein 1 (A)"	--	[R]	General function prediction only	RhoGAP domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Rac GTPase-activating protein 1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rac GTPase-activating protein 1 [Galeopterus variegatus] 
ENSG00000161813(LARP4)	--	26.93266153	2156	29.02713643	2451	29.6651239	2441	29.31928305	2451	27.494646	2382	29.18081624	2545	0.980999357	0.154078015	normal	0.987295781	-0.062584456	normal	0.988175371	0.051870445	normal	0.867131421	0.045002994	normal	--	--	--	"K18763|0|ptr:452428|LARP4; La ribonucleoprotein domain family, member 4; K18763 la-related protein 4 (A)"	--	[T]	Signal transduction mechanisms	La domain	La-related protein 4 GN=LARP4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: la-related protein 4 isoform X2 [Equus caballus]
ENSG00000161835(GRASP)	--	0.484122418	13	0.159937864	4	0.420545426	6	0.092880164	3	0.214112172	3	0.124251972	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF)	General receptor for phosphoinositides 1-associated scaffold protein GN=GRASP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: general receptor for phosphoinositides 1-associated scaffold protein [Erinaceus europaeus]
ENSG00000161847(RAVER1)	--	20.91999158	1247	22.65767062	1315	21.57244342	1321	20.07779841	1170	20.1116989	1192	21.42745202	1272	0.97585757	-0.122629172	normal	0.970512986	-0.162908244	normal	0.981198193	-0.062750025	normal	0.595231857	-0.116508223	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Ribonucleoprotein PTB-binding 1 GN=RAVER1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ribonucleoprotein PTB-binding 1 [Camelus dromedarius]
ENSG00000161850(KRT82)	--	621.6	23026	514.283	19678	589.5599945	22715	934.738	35034	1048.17	38730	858.904538	32035	0.361371671	0.574628351	normal	4.92E-06	0.95538805	normal	0.79157075	0.487684772	normal	0.000117674	0.672317374	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:3888|KRT82, HB2, Hb-2, KRTHB2; keratin 82; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cuticular Hb2 GN=KRT82 OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	"PREDICTED: keratin, type II cuticular Hb2 [Chrysochloris asiatica]"
ENSG00000161860(SYCE2)	--	0.578517401	4	0.331365	9	0.1800559	4	0.1825094	5	0.145055	3	0.110889	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	--	Synaptonemal complex central element protein 2 GN=SYCE2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: synaptonemal complex central element protein 2 isoform X7 [Canis lupus familiaris]
ENSG00000161888(SPC24)	--	9.53671021	355	8.381413	262	11.335122	369	9.067521	336	5.299679	189	6.50752	237	0.962942116	-0.109701923	normal	0.627333117	-0.489266216	normal	0.103705449	-0.643706029	normal	0.337860627	-0.393974991	normal	--	--	--	"K11549|3.00615e-93|hsa:147841|SPC24, SPBC24; SPC24, NDC80 kinetochore complex component; K11549 kinetochore protein Spc24, animal type (A)"	--	--	--	Spc24 subunit of Ndc80	Kinetochore protein Spc24 GN=SPC24 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: kinetochore protein Spc24 isoform X1 [Ursus maritimus]
ENSG00000161896(IP6K3)	--	0.038571011	2	0.171172016	1	0	0	0	0	0.024359536	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: inositol-1,4,5-trisphosphate 3-kinase activity (GO:0008440);; "	"K07756|0|hsa:117283|IP6K3, IHPK3, INSP6K3; inositol hexakisphosphate kinase 3 (EC:2.7.4.21); K07756 inositol-hexakisphosphate kinase [EC:2.7.4.21] (A)"	--	[KIT]	Transcription;; Lipid transport and metabolism;; Signal transduction mechanisms	Inositol polyphosphate kinase	Inositol hexakisphosphate kinase 3 GN=IP6K3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inositol hexakisphosphate kinase 3 [Galeopterus variegatus]
ENSG00000161904(LEMD2)	--	29.95551767	1469	25.08947452	1271	26.61336352	1352	27.1054798	1353	28.84140295	1471	31.31832933	1576	0.974747214	-0.149341996	normal	0.966842303	0.189197262	normal	0.962170436	0.212660422	normal	0.72414429	0.08398637	normal	--	--	Cellular Component: integral component of nuclear inner membrane (GO:0005639);; 	--	--	--	--	Man1-Src1p-C-terminal domain;; LEM domain	LEM domain-containing protein 2 GN=LEMD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LEM domain-containing protein 2 isoform 2 [Orcinus orca]
ENSG00000161905(ALOX15)	--	0	0	0.168134028	1	0.164161011	0	0	0	0.022116836	0	0.022482553	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: protein binding (GO:0005515);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00460|0|hsa:246|ALOX15, 12-LOX, 15-LOX-1, 15LOX-1; arachidonate 15-lipoxygenase (EC:1.13.11.31 1.13.11.33); K00460 arachidonate 15-lipoxygenase [EC:1.13.11.33] (A)"	Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; Serotonergic synapse (ko04726)	--	--	Lipoxygenase;; PLAT/LH2 domain	Arachidonate 15-lipoxygenase GN=ALOX15 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	"PREDICTED: arachidonate 12-lipoxygenase, 12S-type-like isoform 1 [Ceratotherium simum simum]"
ENSG00000161920(MED11)	--	25.84671	345	27.46899	378	28.424967	395	22.802067	319	22.420246	304	24.24837	329	0.958199755	-0.143208695	normal	0.86393873	-0.334247027	normal	0.915359733	-0.270918327	normal	0.339233462	-0.252864066	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	K15131|1.54716e-79|ptr:748337|MED11; mediator complex subunit 11; K15131 mediator of RNA polymerase II transcription subunit 11 (A)	--	[S]	Function unknown	Mediator complex protein	Mediator of RNA polymerase II transcription subunit 11 GN=MED11 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 11 [Pteropus alecto]
ENSG00000161921(CXCL16)	--	12.33746558	395	13.01770094	425	10.09113963	337	6.214385489	204	7.206159579	240	8.185874443	271	0.00010331	-0.978716417	normal	0.002128453	-0.841812198	normal	0.881296869	-0.321136834	normal	0.00072708	-0.715049383	normal	--	--	--	"K10035|6.48941e-180|hsa:58191|CXCL16, CXCLG16, SR-PSOX, SRPSOX; chemokine (C-X-C motif) ligand 16; K10035 C-X-C motif chemokine 16 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	--	C-X-C motif chemokine 16 (Precursor) GN=CXCL16 OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	hypothetical protein PANDA_013822 [Ailuropoda melanoleuca]
ENSG00000161929(SCIMP)	--	0.212845665	8	0.02385702	1	0	0	0.174881208	4	0.051849152	1	0.1104101	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: immunological synapse (GO:0001772);; Cellular Component: integral component of membrane (GO:0016021);; Cellular Component: tetraspanin-enriched microdomain (GO:0097197);; 	--	--	--	--	SCIMP protein	SLP adapter and CSK-interacting membrane protein GN=SCIMP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: SLP adapter and CSK-interacting membrane protein [Galeopterus variegatus]
ENSG00000161939(RNASEK-C17orf49)	--	443.3483658	2601	401.4899907	2349	401.2056442	2341	441.4751896	2595	426.7673238	2395	460.0818541	2652	0.988876086	-0.034143932	normal	0.988050877	0.00654821	normal	0.979896031	0.171560211	normal	0.86011184	0.046595806	normal	--	--	--	--	--	[R]	General function prediction only	--	Chromatin complexes subunit BAP18 GN=BAP18 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"B-cell CLL/lymphoma 6, member B-like protein [Camelus ferus]"
ENSG00000161940(BCL6B)	--	0.0159551	1	0	0	0.078488801	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Zinc-finger double domain;; BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger of C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	B-cell CLL/lymphoma 6 member B protein GN=BCL6B OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: B-cell CLL/lymphoma 6 member B protein [Tupaia chinensis] 
ENSG00000161955(TNFSF13)	--	14.28284707	382	15.64460587	406	15.49127391	424	12.60465066	337	12.34562431	321	14.32989479	387	0.942445511	-0.210753045	normal	0.830665038	-0.358825998	normal	0.960095885	-0.139501136	normal	0.364982004	-0.234570935	normal	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	"K05475|4.2793e-161|ptr:100551504|TNFSF13; tumor necrosis factor (ligand) superfamily, member 13; K05475 tumor necrosis factor ligand superfamily member 13 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Intestinal immune network for IgA production (ko04672);; Rheumatoid arthritis (ko05323)	--	--	TNF(Tumour Necrosis Factor) family	Tumor necrosis factor ligand superfamily member 13 (Precursor) GN=TNFSF13 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor ligand superfamily member 13 [Galeopterus variegatus]
ENSG00000161956(SENP3)	--	40.378226	2027	35.49396493	1845	39.45837231	2055	38.844502	1993	42.20361611	2106	38.67033616	1956	0.986120023	-0.055194449	normal	0.976623858	0.169328083	normal	0.985190767	-0.079463519	normal	0.978728302	0.00974388	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	K08593|0|mcc:715884|SENP3; SUMO1/sentrin/SMT3 specific peptidase 3; K08593 sentrin-specific protease 3 [EC:3.4.22.68] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ulp1 protease family, C-terminal catalytic domain"	Sentrin-specific protease 3 GN=SENP3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sentrin-specific protease 3 [Leptonychotes weddellii]
ENSG00000161958(FGF11)	--	8.967542609	371	8.420512952	357	9.253204232	385	12.37637553	499	11.05904749	420	11.64815753	458	0.750834603	0.39537215	normal	0.941486457	0.212209189	normal	0.930863148	0.241327583	normal	0.222909366	0.285663216	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|1.50095e-158|ptr:748965|FGF11; fibroblast growth factor 11; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 11 GN=FGF11 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 11 isoform X1 [Sus scrofa] 
ENSG00000161960(EIF4A1)	--	574.2748728	17611	544.3952122	16947	556.8002257	17510	621.062664	19008	620.6613689	18861	495.4709376	15155	0.99743709	0.079290987	normal	0.996529447	0.132938456	normal	0.993211676	-0.216656542	normal	0.990067077	0.004479682	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K03257|0|tup:102471270|EIF4A1; eukaryotic translation initiation factor 4A1; K03257 translation initiation factor 4A (A)	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Eukaryotic initiation factor 4A-I GN=EIF4A1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: eukaryotic initiation factor 4A-I isoform X1 [Ochotona princeps]
ENSG00000161970(RPL26)	--	2484.28482	13088	2143.835986	11499	2136.530321	11729	2520.241926	14482	2661.019233	14141	2250.417818	12428	0.996220177	0.115171083	normal	0.984701611	0.276916294	normal	0.996375853	0.075213266	normal	0.49492751	0.155137822	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Biological Process: translation (GO:0006412);; Cellular Component: large ribosomal subunit (GO:0015934);; 	K02898|2.52539e-86|cjc:100414356|60S ribosomal protein L26-like; K02898 large subunit ribosomal protein L26e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	KOW motif	60S ribosomal protein L26 GN=RPL26 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L26 isoform X2 [Pantholops hodgsonii]
ENSG00000161980(POLR3K)	--	26.381049	497	24.518537	471	27.576119	512	23.927382	460	24.680452	462	19.82353	375	0.960980868	-0.141987827	normal	0.969264571	-0.049101579	normal	0.577354567	-0.455964431	normal	0.388641303	-0.212040243	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: zinc ion binding (GO:0008270);; "	"K03019|3.56911e-77|hsa:51728|POLR3K, C11, C11-RNP3, RPC10, RPC11, RPC12.5; polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa; K03019 DNA-directed RNA polymerase III subunit RPC11 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	Transcription factor S-II (TFIIS);; RNA polymerases M/15 Kd subunit	DNA-directed RNA polymerase III subunit RPC10 GN=POLR3K OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC10 [Orcinus orca] 
ENSG00000161981(SNRNP25)	--	28.87646771	620	28.85826133	633	30.87128026	676	37.63691097	820	28.17831736	608	29.11846135	632	0.786734148	0.371720245	normal	0.970627733	-0.079367241	normal	0.969650324	-0.105146802	normal	0.800390892	0.072817774	normal	--	--	--	K13153|2.1822e-92|ptr:467847|SNRNP25; small nuclear ribonucleoprotein 25kDa (U11/U12); K13153 U11/U12 small nuclear ribonucleoprotein 25 kDa protein (A)	--	--	--	Ubiquitin family	U11/U12 small nuclear ribonucleoprotein 25 kDa protein GN=SNRNP25 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U11/U12 small nuclear ribonucleoprotein 25 kDa protein [Camelus bactrianus]
ENSG00000161992(PRR35)	--	0.0993402	4	0	0	0	0	0	0	0.0239864	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-finger	Proline-rich protein 35 GN=PRR35 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: proline-rich protein 35 [Galeopterus variegatus]
ENSG00000161996(WDR90)	--	7.8540372	436	8.42672885	471	6.965389005	456	7.859461263	466	7.936957093	465	8.362752268	474	0.968815504	0.064948161	normal	0.969671185	-0.039794307	normal	0.970130414	0.047407577	normal	0.957636091	0.022640558	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	[K]	Transcription	"WD domain, G-beta repeat;; Protein of unknown function (DUF667);; Nucleoporin Nup120/160"	WD repeat-containing protein 90 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: WD repeat-containing protein 90 [Galeopterus variegatus]
ENSG00000161999(JMJD8)	--	29.25385343	1046	34.62048	1273	31.30058475	1141	33.69823023	1212	36.52595	1307	36.08907815	1300	0.96527636	0.181426857	normal	0.981926436	0.016580725	normal	0.967143835	0.179698113	normal	0.579869857	0.121399442	normal	--	--	--	--	--	[BT]	Chromatin structure and dynamics;; Signal transduction mechanisms	Cupin-like domain;; Cupin superfamily protein	JmjC domain-containing protein 8 GN=JMJD8 OS=Homo sapiens (Human) PE=2 SV=1	BT	Chromatin structure and dynamics;; Signal transduction mechanisms	hypothetical protein CB1_000054013 [Camelus ferus]
ENSG00000162004(CCDC78)	--	1.820018829	25	1.302565807	36	1.972074	33	0.755351585	22	0.539362426	16	1.0057748	23	0.98624294	-0.202011869	normal	0.688988688	-1.119065339	normal	0.969231784	-0.501458981	normal	0.356402082	-0.644975806	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4472)	Coiled-coil domain-containing protein 78 GN=CCDC78 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 78 [Camelus ferus]
ENSG00000162006(MSLNL)	--	0	0	0	0	0	0	0	0	0	0	0.027339435	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Pre-pro-megakaryocyte potentiating factor precursor (Mesothelin)	Mesothelin-like protein (Precursor) GN=MSLNL OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: mesothelin-like protein [Galeopterus variegatus]
ENSG00000162009(SSTR5)	--	0	0	0	0	0.234091	3	0.122248	2	0.0601026	0	0.0616228	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04221|0|hsa:6755|SSTR5, SS-5-R; somatostatin receptor 5; K04221 somatostatin receptor 5 (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv	Somatostatin receptor type 5 GN=SSTR5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: somatostatin receptor type 5 [Ceratotherium simum simum]
ENSG00000162039(MEIOB)	--	1.0592561	31	0.213311	6	0.817737019	26	1.876106	59	2.302597007	62	2.527100054	78	0.665795479	0.866033715	normal	2.22E-08	3.06069786	up	0.001514357	1.523116995	up	0.00038381	1.639875609	up	--	--	--	--	--	[L]	"Replication, recombination and repair"	--	Meiosis-specific with OB domain-containing protein GN=MEIOB OS=Homo sapiens (Human) PE=2 SV=3	L	"Replication, recombination and repair"	PREDICTED: meiosis-specific with OB domain-containing protein isoform X1 [Equus przewalskii]
ENSG00000162040(HS3ST6)	--	1.18171	20	1.08873	19	1.10044	19	0.696334	12	0.564314	9	0.634639	11	0.977026896	-0.697913188	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K09679|0|hsa:64711|HS3ST6, 3-OST-6, HS3ST5, h3-OST-6; heparan sulfate (glucosamine) 3-O-sulfotransferase 6 (EC:2.8.2.23); K09679 [heparan sulfate]-glucosamine 3-sulfotransferase 6 [EC:2.8.2.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase domain	Heparan sulfate glucosamine 3-O-sulfotransferase 6 GN=HS3ST6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan sulfate glucosamine 3-O-sulfotransferase 6 [Lipotes vexillifer]
ENSG00000162062(C16orf59)	--	10.7056854	319	11.98679424	341	13.07122363	382	11.34144335	338	10.29048472	286	11.18570209	341	0.967085971	0.052389418	normal	0.914437778	-0.273855036	normal	0.953352568	-0.171373846	normal	0.683169758	-0.131738626	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C16orf59 GN=C16orf59 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C16orf59 homolog isoformX1 [Equus caballus]
ENSG00000162063(CCNF)	--	10.288053	959	9.72888	914	9.34921	880	11.00253	1021	10.098144	934	8.97349	841	0.978077646	0.059455561	normal	0.978111228	0.00978581	normal	0.97568099	-0.073559841	normal	1	0.000486651	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	"K10289|0|hsa:899|CCNF, FBX1, FBXO1; cyclin F; K10289 F-box protein 1 (cyclin F) (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain;; F-box domain;; F-box-like"	Cyclin-F GN=CCNF OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-F [Equus caballus]
ENSG00000162065(TBC1D24)	--	199.7400679	3395	205.493162	3500	188.1470884	3305	201.1584655	3515	184.8058391	3164	247.2306361	4120	0.991164314	0.01927228	normal	0.983920858	-0.166955967	normal	0.942962111	0.309575508	normal	0.809572548	0.061485646	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TLD;; Rab-GTPase-TBC domain	TBC1 domain family member 24 GN=TBC1D24 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 24 isoform 2 [Equus caballus] 
ENSG00000162068(NTN3)	--	0.473428	14	0.363369	11	0.510495	15	0.0676024	2	0.162816	4	0.265959	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06844|0|hsa:4917|NTN3, NTN2L; netrin 3; K06844 netrin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Laminin EGF-like (Domains III and V);; Laminin N-terminal (Domain VI);; UNC-6/NTR/C345C module	Netrin-3 (Precursor) GN=NTN3 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: netrin-3 [Sus scrofa]
ENSG00000162069(BICDL2)	--	0.0295822	2	0.026024127	1	0.0141543	0	0.026925114	1	0.026193942	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16756|1.88132e-179|hsa:146439|CCDC64B, BICDR-2; coiled-coil domain containing 64B; K16756 coiled-coil domain-containing protein 64 (A)"	--	--	--	--	Bicaudal D-related protein 2 GN=CCDC64B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: bicaudal D-related protein 2 [Ursus maritimus]
ENSG00000162073(PAQR4)	--	20.5073	858	16.80595576	774	21.71372	916	20.64614602	830	17.362108	773	10.573984	498	0.975024669	-0.078555537	normal	0.975806401	-0.023246261	normal	7.12E-05	-0.885479368	normal	0.326583015	-0.300613893	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Progestin and adipoQ receptor family member 4 GN=PAQR4 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: progestin and adipoQ receptor family member 4 [Oryctolagus cuniculus]
ENSG00000162076(FLYWCH2)	--	26.24701095	493	27.45209395	510	24.75057861	474	26.97036603	513	31.74029	549	25.02771589	450	0.971482211	0.026458084	normal	0.968363434	0.084640413	normal	0.96789473	-0.082981743	normal	0.978728302	0.012181221	normal	--	--	--	--	--	--	--	FLYWCH-type zinc finger-containing protein	FLYWCH family member 2 GN=FLYWCH2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: FLYWCH family member 2 isoform X1 [Galeopterus variegatus]
ENSG00000162078(ZG16B)	--	0.729754812	34	0.847767609	29	0.70346505	22	0.725315465	25	0.465297879	15	0.929519202	43	0.972213335	-0.450597071	normal	0.91204623	-0.905764893	normal	0.791572754	0.912904779	normal	0.976471761	-0.05445377	normal	--	--	--	--	--	--	--	--	Zymogen granule protein 16 homolog B (Precursor) GN=ZG16B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: zymogen granule protein 16 homolog B [Galeopterus variegatus]
ENSG00000162086(ZNF75A)	--	5.340475965	436	5.104586264	394	6.686084405	453	7.911855132	570	5.901167457	462	9.46358082	704	0.822985374	0.354705591	normal	0.943583325	0.207534426	normal	0.057190164	0.626083149	normal	0.15731645	0.415797784	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09229|0|pps:100985879|zinc finger protein 75A; K09229 KRAB and SCAN domains-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 75A GN=ZNF75A OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 75D isoform X1 [Equus przewalskii] 
ENSG00000162104(ADCY9)	--	6.065942001	687	3.9936107	564	5.17602	588	7.524988386	941	7.309626308	858	7.41827	927	0.6469633	0.422242631	normal	0.119701051	0.582580831	normal	0.028766274	0.647125062	normal	0.000750638	0.546523444	normal	[T]	Signal transduction mechanisms	Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K08049|0|hsa:115|ADCY9, AC9; adenylate cyclase 9 (EC:4.6.1.1); K08049 adenylate cyclase 9 [EC:4.6.1.1] (A)"	Purine metabolism (ko00230);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; GABAergic synapse (ko04727);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Vasopressin-regulated water reabsorption (ko04962);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Morphine addiction (ko05032);; Vibrio cholerae infection (ko05110);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[R]	General function prediction only	Adenylate and Guanylate cyclase catalytic domain	Adenylate cyclase type 9 GN=ADCY9 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: adenylate cyclase type 9 [Equus caballus] 
ENSG00000162105(SHANK2)	--	6.3508878	1379	5.8914571	1268	9.035821364	1423	6.117182782	1068	5.491263377	1068	7.140266629	1142	0.729140262	-0.399036281	normal	0.932289053	-0.268719948	normal	0.882608722	-0.325277756	normal	0.041791485	-0.333059008	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15009|0|hsa:22941|SHANK2, AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3; SH3 and multiple ankyrin repeat domains 2; K15009 SH3 and multiple ankyrin repeat domains protein (A)"	Glutamatergic synapse (ko04724)	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; Ankyrin repeats (many copies);; SAM domain (Sterile alpha motif);; Ankyrin repeat;; Variant SH3 domain;; Variant SH3 domain;; PDZ domain (Also known as DHR or GLGF);; SH3 domain	SH3 and multiple ankyrin repeat domains protein 2 GN=SHANK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: SH3 and multiple ankyrin repeat domains protein 2 [Equus caballus]
ENSG00000162129(CLPB)	--	8.520531832	518	8.887047022	529	8.04720772	501	6.468610153	402	6.475192999	404	6.349267912	397	0.746474062	-0.395253932	normal	0.719373949	-0.4089966	normal	0.844248251	-0.342797898	normal	0.063354472	-0.385068419	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transcription factor binding (GO:0008134);; Molecular Function: ATPase activity (GO:0016887);; "	K03695|0|ptr:748346|CLPB; ClpB caseinolytic peptidase B homolog (E. coli); K03695 ATP-dependent Clp protease ATP-binding subunit ClpB (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"AAA domain (Cdc48 subfamily);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; C-terminal, D2-small domain, of ClpB protein;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA);; Zeta toxin;; Sigma-54 interaction domain"	Caseinolytic peptidase B protein homolog GN=CLPB OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: caseinolytic peptidase B protein homolog isoform X1 [Pantholops hodgsonii]
ENSG00000162139(NEU3)	--	4.097273	365	4.190115704	334	3.655974352	337	4.553324741	385	3.449719116	321	3.110783301	270	0.968245835	0.045941419	normal	0.964617524	-0.078339511	normal	0.876406919	-0.326440542	normal	0.75165603	-0.10839189	normal	--	--	--	"K12357|0|hsa:10825|NEU3, SIAL3; sialidase 3 (membrane sialidase) (EC:3.2.1.18); K12357 sialidase-2/3/4 [EC:3.2.1.18] (A)"	Other glycan degradation (ko00511);; Sphingolipid metabolism (ko00600)	--	--	BNR repeat-like domain	Sialidase-3 GN=NEU3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sialidase-3 [Galeopterus variegatus]
ENSG00000162144(CYB561A3)	--	46.299353	1620	43.180609	1609	47.495395	1714	44.9247495	1564	40.753597	1447	44.2423958	1616	0.982582255	-0.081506881	normal	0.971751147	-0.174353058	normal	0.982440523	-0.093146699	normal	0.587616794	-0.116328028	normal	--	--	--	K16295|2.5284e-165|ptr:451235|cytochrome b ascorbate-dependent protein 3; K16295 cytochrome b ascorbate-dependent protein 3 [EC:1.16.5.1] (A)	--	[C]	Energy production and conversion	Eukaryotic cytochrome b561	Cytochrome b ascorbate-dependent protein 3 GN=CYB561A3 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: cytochrome b ascorbate-dependent protein 3-like isoform 5 [Dasypus novemcinctus]
ENSG00000162148(PPP1R32)	--	35.89888109	678	35.5474529	684	40.13192694	661	45.15720307	708	41.58107216	767	38.63420559	656	0.974858112	0.031561833	normal	0.965293907	0.143503958	normal	0.974641405	-0.0192018	normal	0.858651877	0.053630626	normal	--	--	--	--	--	--	--	--	Protein phosphatase 1 regulatory subunit 32 GN=PPP1R32 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 32 isoform 1 [Ceratotherium simum simum]
ENSG00000162174(ASRGL1)	--	6.582105372	187	5.722023363	162	6.556942221	203	6.565982018	221	8.43417493	223	5.0577767	179	0.946575772	0.208597958	normal	0.778023965	0.436140034	normal	0.951753288	-0.188316534	normal	0.704388365	0.153122113	normal	[E]	Amino acid transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K13051|0|hsa:80150|ASRGL1, ALP, ALP1, CRASH; asparaginase like 1 (EC:3.5.1.1 3.4.19.5); K13051 beta-aspartyl-peptidase (threonine type) [EC:3.4.19.5] (A)"	--	[E]	Amino acid transport and metabolism	Asparaginase	Isoaspartyl peptidase/L-asparaginase beta chain (Precursor) GN=ASRGL1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: isoaspartyl peptidase/L-asparaginase [Ceratotherium simum simum]
ENSG00000162188(GNG3)	--	0.0955782	1	0.287525	3	0	0	0.564111	6	0.186058	1	0.375789	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04540|5.49046e-49|umr:103678196|GNG3; guanine nucleotide binding protein (G protein), gamma 3; K04540 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Taste transduction (ko04742);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3 (Precursor) GN=GNG3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-3-like protein [Camelus ferus]
ENSG00000162191(UBXN1)	--	47.69957506	1049	36.711267	882	40.85116032	984	48.07867402	1123	55.107187	1261	40.9790004	929	0.978807275	0.067415548	normal	0.382414177	0.493579936	normal	0.975772142	-0.091127	normal	0.507246378	0.163096975	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	UBX domain;; UBA/TS-N domain	UBX domain-containing protein 1 GN=UBXN1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: UBX domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000162194(LBHD1)	--	69.40602443	1330	59.5143259	1192	68.65148641	1339	83.72678926	1531	83.50069917	1530	70.97515981	1421	0.971255344	0.172030441	normal	0.87116528	0.338341117	normal	0.981196417	0.077374313	normal	0.302485627	0.193907501	normal	--	--	--	--	--	--	--	"Cardiac transcription factor regulator, Developmental protein"	LBH domain-containing protein 1 {ECO:0000312|HGNC:HGNC:28351} OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C11orf48 homolog isoform X1 [Bos taurus]
ENSG00000162222(TTC9C)	--	16.17748197	455	17.93725668	472	15.64855224	484	10.816596	329	15.611557	404	16.15223763	481	0.453658583	-0.496629365	normal	0.928632606	-0.245008622	normal	0.971359948	-0.017207662	normal	0.326747188	-0.236917693	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 9C GN=TTC9C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 9C isoform 1 [Equus caballus] 
ENSG00000162227(TAF6L)	--	44.133749	791	40.32875831	790	39.313052	774	46.72658	741	48.3861233	897	50.565685	888	0.969261828	-0.124785917	normal	0.964346613	0.161538428	normal	0.958119957	0.189588585	normal	0.761901642	0.080487757	normal	[K]	Transcription	"Cellular Component: nucleus (GO:0005634);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; Biological Process: regulation of sequence-specific DNA binding transcription factor activity (GO:0051090);; "	"K03131|0|hsa:10629|TAF6L, PAF65A; TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa; K03131 transcription initiation factor TFIID subunit 6 (A)"	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	TATA box binding protein associated factor (TAF);; Protein of unknown function (DUF1546)	TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L GN=TAF6L OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L [Galeopterus variegatus]
ENSG00000162231(NXF1)	--	14.75193846	825	17.20441377	890	16.77754459	907	19.33113783	1037	18.46718867	997	20.08166043	1128	0.901230566	0.298620693	normal	0.969379343	0.142133339	normal	0.89697424	0.305843042	normal	0.177118489	0.24929428	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: mRNA export from nucleus (GO:0006406);; Biological Process: transport (GO:0006810);; Biological Process: mRNA transport (GO:0051028);; 	K14284|0|pps:100995719|NXF1; nuclear RNA export factor 1; K14284 nuclear RNA export factor (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"Tap, RNA-binding;; Nuclear transport factor 2 (NTF2) domain;; TAP C-terminal domain;; Leucine Rich Repeat"	Nuclear RNA export factor 1 GN=NXF1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: nuclear RNA export factor 1 isoform X2 [Tupaia chinensis]
ENSG00000162236(STX5)	--	13.33168915	451	13.03950129	440	12.7305147	436	14.64322302	498	16.8182144	566	15.18432485	508	0.965166812	0.111823435	normal	0.846795743	0.340836723	normal	0.943683102	0.211528596	normal	0.348634804	0.223333207	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	K08490|0|pps:100967290|STX5; syntaxin 5; K08490 syntaxin 5 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain;; Syntaxin	Syntaxin-5 GN=STX5 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-5 [Ovis aries] 
ENSG00000162241(SLC25A45)	--	3.79824831	281	5.0717581	309	4.604518495	300	4.0787445	188	2.558741168	153	5.79728302	350	0.250304411	-0.606585073	normal	0.000143646	-1.028198305	down	0.941896786	0.21310551	normal	0.491612994	-0.384396701	normal	--	--	--	"K15123|0|pps:100980718|SLC25A45; solute carrier family 25, member 45; K15123 solute carrier family 25, member 45/47 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 45 GN=SLC25A45 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 45 [Galeopterus variegatus]
ENSG00000162244(RPL29)	--	930.8702112	9232	808.3300643	7975	809.1758463	8134	896.5545338	9144	920.684927	9161	835.7190007	8479	0.995832284	-0.044642619	normal	0.99152468	0.1785624	normal	0.995369569	0.051628291	normal	0.831204751	0.05843705	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02905|6.08963e-65|oas:101113539|RPL29; ribosomal protein L29; K02905 large subunit ribosomal protein L29e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L29e protein family	60S ribosomal protein L29 GN=RPL29 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L29 isoform X2 [Capra hircus]
ENSG00000162298(SYVN1)	--	16.71902	927	16.49656415	901	18.066436	1001	17.38382769	945	16.704733	917	23.170696	1288	0.978776117	-0.003082214	normal	0.97794669	0.003961479	normal	0.83217559	0.354925274	normal	0.689714633	0.13494928	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10601|0|phd:102343102|SYVN1; synovial apoptosis inhibitor 1, synoviolin; K10601 E3 ubiquitin-protein ligase synoviolin [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Kisspeptin"	E3 ubiquitin-protein ligase synoviolin (Precursor) GN=SYVN1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase synoviolin isoform X2 [Vicugna pacos]
ENSG00000162300(ZFPL1)	--	19.162542	391	19.189492	394	18.754213	380	20.288215	406	21.364138	419	23.889173	487	0.969419245	0.023388666	normal	0.966995062	0.067078373	normal	0.83739203	0.348403152	normal	0.596919322	0.1507285	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Zinc finger protein-like 1 GN=ZFPL1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: zinc finger protein-like 1 [Equus przewalskii] 
ENSG00000162302(RPS6KA4)	--	20.440045	1194	22.20868312	1334	21.5318864	1310	35.35201654	2087	28.53603242	1674	23.27174355	1379	0.000653623	0.77403308	normal	0.912528984	0.305804259	normal	0.981481148	0.065690284	normal	0.139907187	0.398990118	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16510|0|pps:100990698|RPS6KA4; ribosomal protein S6 kinase, 90kDa, polypeptide 4; K16510 ribosomal protein S6 kinase alpha-4 [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; TNF signaling pathway (ko04668)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Phosphotransferase enzyme family;; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family;; Protein kinase C terminal domain	Ribosomal protein S6 kinase alpha-4 GN=RPS6KA4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ribosomal protein S6 kinase alpha-4 [Vicugna pacos]
ENSG00000162337(LRP5)	--	47.05409	4628	38.82588	4129	40.62606	4354	30.67665	3275	31.79677	3341	30.54251	3030	0.278522834	-0.529516079	normal	0.932194916	-0.326805648	normal	0.266195357	-0.53109268	normal	0.001924834	-0.464149308	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K03068|0|ptr:451380|LRP5; low density lipoprotein receptor-related protein 5; K03068 low density lipoprotein receptor-related protein 5/6 (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; Low-density lipoprotein receptor domain class A;; SMP-30/Gluconolaconase/LRE-like region;; Arylesterase;; NHL repeat	Low-density lipoprotein receptor-related protein 5 (Precursor) GN=LRP5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 5 [Tupaia chinensis]
ENSG00000162341(TPCN2)	--	5.866082029	400	4.290873812	336	5.468893741	392	5.897438557	364	6.621038367	446	5.791674401	370	0.954587313	-0.166224151	normal	0.78282662	0.385644914	normal	0.965550804	-0.091257391	normal	0.908108189	0.044131751	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14077|0|hsa:219931|TPCN2, SHEP10, TPC2; two pore segment channel 2; K14077 two pore calcium channel protein 2 (A)"	Pancreatic secretion (ko04972)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein	Two pore calcium channel protein 2 GN=TPCN2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: two pore calcium channel protein 2 [Galeopterus variegatus]
ENSG00000162344(FGF19)	--	0.150773	6	0.270582	11	0.0239445	0	0	0	0.0485607	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K04358|5.0061e-146|hsa:9965|FGF19; fibroblast growth factor 19; K04358 fibroblast growth factor (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[T]	Signal transduction mechanisms	Fibroblast growth factor	Fibroblast growth factor 19 (Precursor) GN=FGF19 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor 19 [Felis catus]
ENSG00000162366(PDZK1IP1)	--	1.202740853	16	0.922038887	12	1.055365561	13	104.9348907	1372	88.68720012	1149	101.59748	1330	0	6.2619285	up	0	6.391647398	up	0	6.511792227	up	3.65E-185	6.532033016	up	--	--	--	--	--	--	--	--	PDZK1-interacting protein 1 GN=PDZK1IP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: PDZK1-interacting protein 1 [Felis catus]
ENSG00000162367(TAL1)	--	0.025468137	2	0	0	0	0	0	0	0.037160685	2	0.012646518	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09068|0|hsa:6886|TAL1, SCL, TCL5, bHLHa17, tal-1; T-cell acute lymphocytic leukemia 1; K09068 T-cell acute lymphocytic leukemia protein (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	T-cell acute lymphocytic leukemia protein 1 GN=TAL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: T-cell acute lymphocytic leukemia protein 1 [Galeopterus variegatus]
ENSG00000162368(CMPK1)	--	56.2668107	2169	59.93715558	2327	56.47891977	2143	75.639238	2898	66.09613122	2514	62.965619	2367	0.813296485	0.386957437	normal	0.986234643	0.090030582	normal	0.982723036	0.135045703	normal	0.248287699	0.206685685	normal	[F]	Nucleotide transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Molecular Function: kinase activity (GO:0016301);; 	"K13800|1.0654e-154|ptr:456837|CMPK1, CMPK; cytidine monophosphate (UMP-CMP) kinase 1, cytosolic; K13800 UMP-CMP kinase [EC:2.7.4.- 2.7.4.14] (A)"	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Adenylate kinase;; AAA domain;; AAA domain;; Thymidylate kinase;; AAA domain;; Zeta toxin	UMP-CMP kinase {ECO:0000255|HAMAP-Rule:MF_03172} OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: UMP-CMP kinase-like [Tupaia chinensis]
ENSG00000162373(BEND5)	--	0	0	0	0	0	0	0	0	0.0876397	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	BEN domain	BEN domain-containing protein 5 GN=BEND5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: BEN domain-containing protein 5-like [Odobenus rosmarus divergens] 
ENSG00000162374(ELAVL4)	--	0.022918638	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13208|0|hgl:101725151|Elavl4; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4; K13208 ELAV like protein 2/3/4 (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	ELAV-like protein 4 GN=ELAVL4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ELAV-like protein 4 isoform X1 [Camelus bactrianus]
ENSG00000162377(COA7)	--	8.982541	716	9.607753911	773	9.146378863	728	8.459477	678	9.676302	769	7.947722	634	0.969885815	-0.109265577	normal	0.975649253	-0.028854777	normal	0.949536625	-0.207285241	normal	0.653965111	-0.112685262	normal	[R]	General function prediction only	--	K18180|3.29486e-171|ptr:469326|SELRC1; Sel1 repeat containing 1; K18180 cytochrome c oxidase assembly factor 7 (A)	--	[S]	Function unknown	Sel1 repeat	Cytochrome c oxidase assembly factor 7 GN=COA7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cytochrome c oxidase assembly factor 7 [Galeopterus variegatus]
ENSG00000162378(ZYG11B)	--	6.918064729	891	7.65411196	981	7.61272725	959	6.553617551	850	6.726893	831	6.200795686	800	0.973833802	-0.098620711	normal	0.930801158	-0.260394491	normal	0.923968079	-0.269356525	normal	0.283165922	-0.211732118	normal	--	--	--	"K10350|0|ptr:738327|ZYG11B; zyg-11 family member B, cell cycle regulator; K10350 Zyg-11 protein homolog (A)"	--	[R]	General function prediction only	--	Protein zyg-11 homolog B GN=ZYG11B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein zyg-11 homolog B [Orcinus orca]
ENSG00000162384(C1orf123)	--	13.0341	247	13.0217	249	11.3728	217	11.9027	227	13.8975	261	15.3745	292	0.956668569	-0.151666475	normal	0.96527505	0.046203415	normal	0.765021263	0.417465101	normal	0.780259177	0.108918853	normal	--	--	--	--	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF866)	UPF0587 protein C1orf123 GN=C1orf123 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0587 protein C1orf123 homolog isoform X1 [Felis catus]
ENSG00000162385(MAGOH)	--	24.22109	239	26.63193	257	29.61848	289	35.18646	347	32.00362	307	29.45036	281	0.502423466	0.50438812	normal	0.934260632	0.23378372	normal	0.966647475	-0.048533237	normal	0.429830998	0.230696758	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K12877|3.20395e-103|tup:102484886|MAGOH; mago-nashi homolog, proliferation-associated (Drosophila); K12877 protein mago nashi (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040)	[A]	RNA processing and modification	Mago nashi protein	Protein mago nashi homolog GN=MAGOH OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"hypothetical protein M91_12348, partial [Bos mutus]"
ENSG00000162390(ACOT11)	--	1.6613249	113	1.266038644	89	1.4061583	112	0.30793346	26	0.60661241	35	0.607571506	34	1.14E-08	-2.086156673	down	0.004024028	-1.330535437	down	5.29E-06	-1.684517921	down	4.82E-06	-1.744863227	down	[I]	Lipid transport and metabolism	Molecular Function: lipid binding (GO:0008289);; 	"K12417|0|hsa:26027|ACOT11, BFIT, STARD14, THEA, THEM1; acyl-CoA thioesterase 11 (EC:3.1.2.-); K12417 acyl-CoA thioesteraes 11 [EC:3.1.2.-] (A)"	--	[I]	Lipid transport and metabolism	START domain;; Thioesterase superfamily	Acyl-coenzyme A thioesterase 11 GN=ACOT11 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-coenzyme A thioesterase 11 [Galeopterus variegatus]
ENSG00000162391(FAM151A)	--	0.560254	22	1.10206	44	0.417803	16	0.228994	9	0.346487	13	0.276762	11	0.898869421	-1.187084963	normal	0.031368373	-1.668935563	normal	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2181)	Protein FAM151A GN=FAM151A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM151A [Orycteropus afer afer]
ENSG00000162396(PARS2)	--	2.77703	120	2.298571	102	3.057768	134	3.35585	150	3.012747	133	3.168409	155	0.934254692	0.287794658	normal	0.911617178	0.35678633	normal	0.953611502	0.199647131	normal	0.509389078	0.278285976	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01881|0|hsa:25973|PARS2, MT-PRORS; prolyl-tRNA synthetase 2, mitochondrial (putative) (EC:6.1.1.15); K01881 prolyl-tRNA synthetase [EC:6.1.1.15] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain"	"Probable proline--tRNA ligase, mitochondrial (Precursor) GN=PARS2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable proline--tRNA ligase, mitochondrial [Galeopterus variegatus]"
ENSG00000162402(USP24)	--	11.74333609	2198	12.473861	2380	11.70491679	2127	10.33540223	1947	11.19598602	2066	11.332109	2099	0.970780831	-0.205617927	normal	0.967147827	-0.225394007	normal	0.98719727	-0.027389705	normal	0.430205206	-0.154685709	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11840|0|hsa:23358|USP24; ubiquitin specific peptidase 24 (EC:3.4.19.12); K11840 ubiquitin carboxyl-terminal hydrolase 9/24 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 24 GN=USP24 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 24 [Mustela putorius furo]
ENSG00000162407(PLPP3)	--	7.074741	411	5.946250465	346	5.509528733	320	5.301186	309	8.411312	491	10.476037	613	0.655553718	-0.440457519	normal	0.509672115	0.481748683	normal	7.33E-05	0.926306241	normal	0.494146558	0.372307504	normal	[I]	Lipid transport and metabolism	--	"K01080|0|hsa:8613|PPAP2B, Dri42, LPP3, PAP2B, VCIP; phosphatidic acid phosphatase type 2B (EC:3.1.3.4); K01080 phosphatidate phosphatase [EC:3.1.3.4] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Sphingolipid metabolism (ko00600);; Fc gamma R-mediated phagocytosis (ko04666);; Fat digestion and absorption (ko04975);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	PAP2 superfamily	Lipid phosphate phosphohydrolase 3 GN=PPAP2B OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: lipid phosphate phosphohydrolase 3 isoform X1 [Tupaia chinensis] 
ENSG00000162408(NOL9)	--	3.96614	439	4.42559	492	4.20942	464	4.72101	524	4.3889	484	3.90946	434	0.938960349	0.223795993	normal	0.969901094	-0.044938557	normal	0.965625452	-0.104369404	normal	0.948366015	0.026024728	normal	[R]	General function prediction only	--	"K06947|0|hsa:79707|NOL9, Grc3, NET6; nucleolar protein 9 (EC:2.3.1.50); K06947 polynucleotide 5'-hydroxyl-kinase GRC3/NOL9 [EC:2.7.1.-] (A)"	--	[R]	General function prediction only	Pre-mRNA cleavage complex II protein Clp1;; Molybdopterin guanine dinucleotide synthesis protein B	Polynucleotide 5'-hydroxyl-kinase NOL9 GN=NOL9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: polynucleotide 5'-hydroxyl-kinase NOL9 [Pteropus alecto] 
ENSG00000162409(PRKAA2)	--	4.575743318	617	4.86466283	642	5.260794953	684	4.447851129	605	4.849786992	654	4.014649563	542	0.972331579	-0.059019186	normal	0.973918584	0.005278462	normal	0.839665924	-0.343140635	normal	0.605068297	-0.130783727	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07198|0|ptr:741802|PRKAA2; protein kinase, AMP-activated, alpha 2 catalytic subunit; K07198 5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11] (A)"	FoxO signaling pathway (ko04068);; Regulation of autophagy (ko04140);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Circadian rhythm (ko04710);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Oxytocin signaling pathway (ko04921);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hypertrophic cardiomyopathy (HCM) (ko05410)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	5'-AMP-activated protein kinase catalytic subunit alpha-2 GN=PRKAA2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: 5'-AMP-activated protein kinase catalytic subunit alpha-2 [Dasypus novemcinctus]
ENSG00000162413(KLHL21)	--	8.013302663	534	7.379431775	621	6.708833504	500	10.69007036	877	11.4878402	896	15.3732377	1279	0.013883949	0.683356266	normal	0.343862038	0.506446894	normal	1.72E-12	1.344090096	up	0.00614961	0.862572616	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10458|0|ptr:457900|KLHL21; kelch-like family member 21; K10458 kelch-like protein 21 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 21 GN=KLHL21 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 21 [Ceratotherium simum simum]
ENSG00000162415(ZSWIM5)	--	0.462746731	43	0.788393381	62	0.46974164	34	0.920829529	82	1.12433772	111	0.84931516	80	0.377858562	0.877401988	normal	0.287645544	0.803947446	normal	0.03579274	1.190661261	normal	0.021416782	0.951928015	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[S]	Function unknown	--	Zinc finger SWIM domain-containing protein 5 GN=ZSWIM5 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	"PREDICTED: zinc finger SWIM domain-containing protein 5, partial [Bison bison bison]"
ENSG00000162419(GMEB1)	--	4.79948322	317	4.0745795	299	3.811842175	283	4.148670692	321	3.806249626	325	3.076874456	279	0.968055137	-0.012680731	normal	0.96265433	0.098390276	normal	0.967242081	-0.028674049	normal	0.970604033	0.019435087	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	SAND domain	Glucocorticoid modulatory element-binding protein 1 GN=GMEB1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: glucocorticoid modulatory element-binding protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000162426(SLC45A1)	--	7.6990257	337	7.056756227	304	6.181127072	273	1.332348068	64	2.427907358	101	2.051692043	88	0	-2.399342144	down	1.31E-10	-1.596649027	down	1.86E-10	-1.624911637	down	4.89E-15	-1.873480869	down	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K15378|0|hsa:50651|SLC45A1, DNB5; solute carrier family 45, member 1; K15378 solute carrier family 45, member 1/2/4 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; MFS/sugar transport protein	Proton-associated sugar transporter A GN=SLC45A1 OS=Homo sapiens (Human) PE=2 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: proton-associated sugar transporter A [Orycteropus afer afer]
ENSG00000162430(SELENON)	--	45.20834166	3729	37.8558522	3101	42.75253469	3536	36.29603856	2954	39.85552909	3262	33.92671948	2802	0.874502771	-0.366780989	normal	0.989856358	0.051572176	normal	0.904064658	-0.3437872	normal	0.21170629	-0.222154562	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	--	Selenoprotein N (Precursor) GN=SEPN1 OS=Homo sapiens (Human) PE=1 SV=5	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: selenoprotein N [Chrysochloris asiatica]
ENSG00000162433(AK4)	--	18.90925941	1192	24.22739503	1472	20.30966028	1159	21.31590379	1434	12.83707337	863	15.98376178	961	0.951548591	0.235551411	normal	0.000674008	-0.790697537	normal	0.922418916	-0.27816446	normal	0.542395782	-0.253677081	normal	[F]	Nucleotide transport and metabolism	Molecular Function: adenylate kinase activity (GO:0004017);; Molecular Function: cytidylate kinase activity (GO:0004127);; Molecular Function: ATP binding (GO:0005524);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; 	K00939|1.60989e-165|pps:100973225|AK4; adenylate kinase 4; K00939 adenylate kinase [EC:2.7.4.3] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	"Adenylate kinase;; Adenylate kinase, active site lid;; AAA domain;; AAA domain"	"Adenylate kinase 4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03170} OS=Homo sapiens (Human) PE=1 SV=1"	F	Nucleotide transport and metabolism	"PREDICTED: adenylate kinase isoenzyme 4, mitochondrial [Orcinus orca] "
ENSG00000162434(JAK1)	--	48.17759	5000	59.60539003	6176	54.10537	5568	62.808347	6517	61.72074	6360	68.69436	7108	0.927224043	0.351352836	normal	0.9942647	0.020922407	normal	0.938258751	0.343910161	normal	0.205599622	0.234275401	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K11217|0|hsa:3716|JAK1, JAK1A, JAK1B, JTK3; Janus kinase 1 (EC:2.7.10.2); K11217 Janus kinase 1 [EC:2.7.10.2] (A)"	PI3K-Akt signaling pathway (ko04151);; Osteoclast differentiation (ko04380);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Pancreatic cancer (ko05212)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Tyrosine-protein kinase JAK1 GN=JAK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase JAK1 [Odobenus rosmarus divergens]
ENSG00000162437(RAVER2)	--	5.05258005	357	5.96239	423	5.218129	366	5.03741	359	4.899377	346	4.19011	297	0.968627567	-0.02267518	normal	0.885022944	-0.310084094	normal	0.889914972	-0.308255548	normal	0.430205206	-0.215598269	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Ribonucleoprotein PTB-binding 2 GN=RAVER2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribonucleoprotein PTB-binding 2 [Loxodonta africana]
ENSG00000162438(CTRC)	--	0.01547174	1	0.0760722	5	0.0150268	0	0.015566667	1	0.030280908	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01311|0|hsa:11330|CTRC, CLCR, ELA4; chymotrypsin C (caldecrin) (EC:3.4.21.2); K01311 chymotrypsin C [EC:3.4.21.2] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin	Chymotrypsin-C (Precursor) GN=CTRC OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: chymotrypsin-C [Tupaia chinensis] 
ENSG00000162441(LZIC)	--	14.049126	670	17.23446025	835	13.946399	721	15.93511367	747	13.927082	628	14.18268679	814	0.968055329	0.125841504	normal	0.630978069	-0.431533646	normal	0.962420582	0.166409414	normal	0.890037057	-0.045312312	normal	--	--	Molecular Function: beta-catenin binding (GO:0008013);; 	--	--	--	--	Beta-catenin-interacting protein ICAT	Protein LZIC GN=LZIC OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein LZIC [Orcinus orca] 
ENSG00000162444(RBP7)	--	1.6572	13	1.63001	13	2.06821	16	0.477585	4	0.990634	7	0.49202	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family	Retinoid-binding protein 7 GN=RBP7 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	retinoid-binding protein 7 [Sus scrofa] 
ENSG00000162458(FBLIM1)	--	25.21048485	1062	17.60047159	886	23.41643594	975	21.29208886	1024	20.745602	1063	13.68878457	593	0.977370214	-0.083277605	normal	0.94261735	0.24096052	normal	0.004637511	-0.724206045	normal	0.754561271	-0.147694652	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	LIM domain	Filamin-binding LIM protein 1 GN=FBLIM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: filamin-binding LIM protein 1 [Vicugna pacos]
ENSG00000162460(TMEM82)	--	0.0491071	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 82 GN=TMEM82 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 82 [Galeopterus variegatus]
ENSG00000162461(SLC25A34)	--	0.181826	9	0.177786	9	0.175053	8	0.222108	11	0.353319	17	0.279749	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15117|0|hsa:284723|SLC25A34; solute carrier family 25, member 34; K15117 solute carrier family 25, member 34/35 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 34 GN=SLC25A34 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 34 [Trichechus manatus latirostris]
ENSG00000162482(AKR7A3)	--	0.102798	3	0.201202	6	0.0977065	2	0.101463	3	0.0992653	2	0.135163	4	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	--	"K15303|0|hsa:22977|AKR7A3, AFAR2; aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase); K15303 aflatoxin B1 aldehyde reductase (A)"	Metabolism of xenobiotics by cytochrome P450 (ko00980)	--	--	Aldo/keto reductase family	Aflatoxin B1 aldehyde reductase member 3 GN=AKR7A3 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: aflatoxin B1 aldehyde reductase member 4-like [Trichechus manatus latirostris]
ENSG00000162490(DRAXIN)	--	0.0194861	3	0.0128566	2	0.0381104	5	0.0713197	11	0.0504694	7	0.109294	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: axon guidance (GO:0007411);; Biological Process: Wnt signaling pathway (GO:0016055);; 	--	--	--	--	Draxin	Draxin {ECO:0000255|HAMAP-Rule:MF_03060} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: draxin [Tupaia chinensis] 
ENSG00000162493(PDPN)	--	0	0	0	0	0	0	0.140404186	1	0.022744403	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K16778|1.24593e-121|ptr:456453|PDPN; podoplanin; K16778 podoplanin (A)	--	--	--	Podoplanin	Podoplanin (Precursor) OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: podoplanin [Odobenus rosmarus divergens]
ENSG00000162494(LRRC38)	--	0	0	0	0	0	0	0.0264507	1	0.103468	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Leucine-rich repeat-containing protein 38 (Precursor) GN=LRRC38 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 38 [Sus scrofa]
ENSG00000162496(DHRS3)	--	40.702333	1477	43.60431008	1441	30.82519	1048	38.9159696	1273	43.197704	1524	44.6985285	1431	0.948607625	-0.244994833	normal	0.982426295	0.059305486	normal	0.586123278	0.440547364	normal	0.841306991	0.070958813	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K11146|0|ptr:737006|DHRS3; dehydrogenase/reductase (SDR family) member 3; K11146 short-chain dehydrogenase/reductase 3 [EC:1.1.1.300] (A)	Retinol metabolism (ko00830)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase;; Polysaccharide biosynthesis protein;; NAD dependent epimerase/dehydratase family	Short-chain dehydrogenase/reductase 3 GN=DHRS3 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: short-chain dehydrogenase/reductase 3 isoform X1 [Bos mutus] 
ENSG00000162510(MATN1)	--	0.0135342	1	0.0131372	1	0.221982	16	0.0134791	1	0.0396535	2	0.0269283	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	von Willebrand factor type A domain;; von Willebrand factor type A domain;; Trimeric coiled-coil oligomerisation domain of matrilin;; von Willebrand factor type A domain;; Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; Calcium-binding EGF domain	Cartilage matrix protein (Precursor) GN=MATN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cartilage matrix protein [Ceratotherium simum simum]
ENSG00000162511(LAPTM5)	--	0.097105592	3	0.130014658	4	0.2177638	6	0.556124363	18	0.558319	17	0.158351828	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K12387|3.93735e-172|hsa:7805|LAPTM5, CLAST6; lysosomal protein transmembrane 5; K12387 lysosomal-associated transmembrane protein (A)"	Lysosome (ko04142)	--	--	Golgi 4-transmembrane spanning transporter	Lysosomal-associated transmembrane protein 5 GN=LAPTM5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lysosomal-associated transmembrane protein 5 [Eptesicus fuscus]
ENSG00000162512(SDC3)	--	10.43850846	1160	9.21761902	1038	9.395256	1071	8.067406211	894	9.906299949	1088	7.174366	759	0.701315104	-0.405995781	normal	0.979018695	0.046379553	normal	0.320546633	-0.504228066	normal	0.182802281	-0.275663165	normal	--	--	--	K16337|1.01819e-86|ptr:744364|SDC3; syndecan 3; K16337 syndecan 3 (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Syndecan domain	Syndecan-3 GN=SDC3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: syndecan-3 isoform X2 [Chrysochloris asiatica]
ENSG00000162517(PEF1)	--	25.8475	708	29.3705	818	26.4834	735	29.4899	811	31.2794	848	30.6243	840	0.962436148	0.164785994	normal	0.976540453	0.030481517	normal	0.958717603	0.183999263	normal	0.605455032	0.123228036	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair	Peflin GN=PEF1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: peflin [Ochotona princeps]
ENSG00000162520(SYNC)	--	6.456458	415	6.500912	423	6.53525	470	6.59177	475	6.766861	464	6.06909	432	0.956249908	0.163418113	normal	0.963829736	0.111659345	normal	0.962516176	-0.129486165	normal	0.896585106	0.046610869	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K10377|0|pon:100460936|SYNC; syncoilin, intermediate filament protein; K10377 syncoilin 1 (A)"	--	--	--	Intermediate filament protein	Syncoilin GN=SYNC OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: syncoilin isoform X1 [Loxodonta africana]
ENSG00000162521(RBBP4)	--	53.21889558	2458	59.87051314	2677	61.06594725	2620	53.17516974	2598	51.36018427	2554	53.06454554	2347	0.988360275	0.049054426	normal	0.987018349	-0.089233556	normal	0.980445829	-0.166938547	normal	0.774678062	-0.06988518	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10752|0|acs:100561534|rbbp4; retinoblastoma binding protein 4; K10752 histone-binding protein RBBP4 (A)	--	[B]	Chromatin structure and dynamics	"WD domain, G-beta repeat;; Histone-binding protein RBBP4 or subunit C of CAF1 complex;; Eukaryotic translation initiation factor eIF2A"	Histone-binding protein RBBP4 GN=RBBP4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: histone-binding protein RBBP4 [Oryctolagus cuniculus]
ENSG00000162522(KIAA1522)	--	20.63346423	2221	22.99714305	2428	24.75291096	2656	24.10696801	2529	22.53195944	2411	22.92812263	2471	0.981123575	0.156423927	normal	0.98800265	-0.031543612	normal	0.985869426	-0.112385219	normal	1	-0.000264478	normal	--	--	--	--	--	--	--	NHS-like	Uncharacterized protein KIAA1522 GN=KIAA1522 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA1522 homolog [Equus caballus]
ENSG00000162526(TSSK3)	--	1.42448	35	2.86012	73	1.27881	32	1.64534	41	1.54691	38	4.28447	60	0.979906777	0.189735885	normal	0.340954083	-0.935976074	normal	0.640235991	0.86818201	normal	0.986717177	-0.031422457	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08811|0|hsa:81629|TSSK3, SPOGA3, STK22C, STK22D, TSK3; testis-specific serine kinase 3 (EC:2.7.11.1); K08811 testis-specific serine kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Testis-specific serine/threonine-protein kinase 3 GN=TSSK3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: testis-specific serine/threonine-protein kinase 3 [Condylura cristata]
ENSG00000162542(TMCO4)	--	2.49267555	159	2.179502877	139	2.162945709	143	2.348348697	148	2.478839669	156	2.679354893	167	0.961766428	-0.132930022	normal	0.959591132	0.14355968	normal	0.949779641	0.213450772	normal	0.892992905	0.074084322	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF726);; Alpha/beta hydrolase of unknown function (DUF900)	Transmembrane and coiled-coil domain-containing protein 4 GN=TMCO4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane and coiled-coil domain-containing protein 4 isoform X2 [Tupaia chinensis]
ENSG00000162545(CAMK2N1)	--	37.1509	1125	30.7186	933	36.2906	1107	35.6521	1086	44.5309	1357	45.7823	1398	0.978209947	-0.081619696	normal	0.283152675	0.518344779	normal	0.878126984	0.328018085	normal	0.222189846	0.259051494	normal	--	--	--	--	--	--	--	Calcium/calmodulin-dependent protein kinase II inhibitor	Calcium/calmodulin-dependent protein kinase II inhibitor 1 GN=CAMK2N1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	calcium/calmodulin-dependent protein kinase II inhibitor 1 [Bos taurus] 
ENSG00000162551(ALPL)	--	0.139971556	5	0.02170067	1	0.021621486	0	0.066919972	3	0.117515768	1	0.021569337	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: phosphatase activity (GO:0016791);; 	"K01077|0|hsa:249|ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP; alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1); K01077 alkaline phosphatase [EC:3.1.3.1] (A)"	Folate biosynthesis (ko00790)	[P]	Inorganic ion transport and metabolism	Alkaline phosphatase	"Alkaline phosphatase, tissue-nonspecific isozyme (Precursor) GN=ALPL OS=Homo sapiens (Human) PE=1 SV=4"	P	Inorganic ion transport and metabolism	"PREDICTED: alkaline phosphatase, tissue-nonspecific isozyme isoform X1 [Panthera tigris altaica] "
ENSG00000162552(WNT4)	--	0.231492326	20	0.103484428	9	0.157768851	13	0.069788952	6	0.311584631	11	0.057185018	5	0.791479127	-1.541412393	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00408|0|mcc:707864|WNT4; wingless-type MMTV integration site family, member 4; K00408 wingless-type MMTV integration site family, member 4 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; Thyroid hormone signaling pathway (ko04919);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-4 (Precursor) GN=WNT4 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	"PREDICTED: protein Wnt-4 isoform X1, partial [Sus scrofa]"
ENSG00000162572(SCNN1D)	--	1.753979814	107	1.821463416	96	1.093098569	75	0.766824959	44	0.984391505	41	1.23225774	74	0.001761452	-1.283179314	down	0.008500414	-1.218583439	down	0.973862348	-0.027106509	normal	0.045730928	-0.826169797	normal	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	"K04826|0|hsa:6339|SCNN1D, ENaCd, ENaCdelta, SCNED, dNaCh; sodium channel, non-voltage-gated 1, delta subunit; K04826 amiloride-sensitive sodium channel subunit delta (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Amiloride-sensitive sodium channel subunit delta GN=SCNN1D OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: amiloride-sensitive sodium channel subunit delta [Galeopterus variegatus]
ENSG00000162576(MXRA8)	--	0.873108527	34	1.069842824	41	1.234784119	48	1.193646527	46	0.76665862	32	0.935354163	38	0.966929351	0.390066879	normal	0.970027198	-0.363751748	normal	0.969067019	-0.333491373	normal	0.912673719	-0.10605663	normal	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	Matrix-remodeling-associated protein 8 (Precursor) GN=MXRA8 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: matrix-remodeling-associated protein 8 [Trichechus manatus latirostris]
ENSG00000162585(FAAP20)	--	41.7048	488	36.75973	438	37.19442	518	25.97782	355	27.4759	349	30.165114	395	0.46982115	-0.488084123	normal	0.842697182	-0.347781952	normal	0.741844358	-0.398055859	normal	0.047748787	-0.414539334	normal	--	--	--	--	--	--	--	--	Fanconi anemia-associated protein of 20 kDa GN=FAAP20 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: Fanconi anemia-associated protein of 20 kDa [Ceratotherium simum simum]
ENSG00000162591(MEGF6)	--	11.02031971	1330	8.605908949	1096	8.635180078	1171	4.1489344	554	3.633695561	431	5.578212488	700	1.07E-11	-1.291910239	down	3.09E-12	-1.3647984	down	0.001993848	-0.74933992	normal	5.72E-09	-1.114631419	down	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Coagulation Factor Xa inhibitory site;; Laminin EGF-like (Domains III and V);; Calcium-binding EGF domain;; Complement Clr-like EGF-like	Multiple epidermal growth factor-like domains protein 6 (Precursor) GN=MEGF6 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: multiple epidermal growth factor-like domains protein 6 [Galeopterus variegatus]
ENSG00000162595(DIRAS3)	--	0	0	0	0	0.0297192	0	0.878804	29	0.856182	28	1.08644	36	1.99E-05	4.298274664	up	2.99E-05	4.276384366	up	2.12E-07	4.628585253	up	1.06E-12	Inf	up	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07842|6.86023e-148|ptr:456930|DIRAS3; DIRAS family, GTP-binding RAS-like 3; K07842 DIRAS family, GTP-binding Ras-like 3 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; AAA domain	GTP-binding protein Di-Ras3 (Precursor) GN=DIRAS3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	GTP-binding protein Di-Ras3 [Sus scrofa] 
ENSG00000162599(NFIA)	--	3.323556747	255	4.193391216	293	4.3306246	256	4.807636145	371	5.5003284	430	4.529099726	344	0.473249592	0.507541358	normal	0.371502273	0.529739809	normal	0.745012114	0.415846793	normal	0.03078148	0.488624054	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09168|0|rno:25492|Nfia; nuclear factor I/A; K09168 nuclear factor I/A (A)	--	[K]	Transcription	CTF/NF-I family transcription modulation region;; Nuclear factor I protein pre-N-terminus;; MH1 domain	Nuclear factor 1 A-type GN=NFIA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear factor 1 A-type isoform X4 [Oryctolagus cuniculus]
ENSG00000162600(OMA1)	--	7.791797833	191	5.457828044	154	7.66924928	204	7.708560606	196	10.8030893	242	8.031622113	220	0.967036157	0.006397948	normal	0.274200404	0.625710143	normal	0.963021392	0.099929441	normal	0.494966685	0.240858828	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M48	"Metalloendopeptidase OMA1, mitochondrial (Precursor) GN=OMA1 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: metalloendopeptidase OMA1, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000162601(MYSM1)	--	5.490519255	638	5.200786708	587	5.594838059	625	5.558687969	660	5.977440801	655	5.63255916	642	0.974392022	0.018034637	normal	0.964300457	0.136375124	normal	0.973968908	0.030353199	normal	0.843370735	0.059906289	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11865|0|hsa:114803|MYSM1, 2A-DUB, 2ADUB; Myb-like, SWIRM and MPN domains 1 (EC:3.1.2.15); K11865 protein MYSM1 (A)"	--	[B]	Chromatin structure and dynamics	SWIRM domain;; JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Myb-like DNA-binding domain;; Prokaryotic homologs of the JAB domain	Histone H2A deubiquitinase MYSM1 GN=MYSM1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone H2A deubiquitinase MYSM1 isoform X1 [Galeopterus variegatus]
ENSG00000162604(TM2D1)	--	18.57793357	218	23.93605771	209	17.01964173	198	11.76934842	166	17.17810866	193	13.76420677	177	0.802147123	-0.420568423	normal	0.958295598	-0.135309454	normal	0.955393234	-0.168679115	normal	0.497383076	-0.242683843	normal	--	--	--	--	--	[R]	General function prediction only	TM2 domain	TM2 domain-containing protein 1 (Precursor) GN=TM2D1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: TM2 domain-containing protein 1 [Trichechus manatus latirostris]
ENSG00000162607(USP1)	--	14.62263978	1038	17.34172675	1232	16.36880848	1145	15.00763771	1078	15.8302596	1126	14.56445173	1040	0.979993776	0.023684071	normal	0.971466501	-0.151027985	normal	0.971344932	-0.146851911	normal	0.687403217	-0.095392917	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11832|0|hsa:7398|USP1, UBP; ubiquitin specific peptidase 1 (EC:3.4.19.12); K11832 ubiquitin carboxyl-terminal hydrolase 1 [EC:3.4.19.12] (A)"	Fanconi anemia pathway (ko03460)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 1 GN=USP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 1 isoform X1 [Mustela putorius furo] 
ENSG00000162613(FUBP1)	--	42.4905842	2363	49.7014184	2757	47.45207809	2512	51.03326329	2767	47.83385068	2686	38.311315	2094	0.976266493	0.196752441	normal	0.98843691	-0.059033712	normal	0.950372052	-0.270687716	normal	0.900709545	-0.038175818	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K13210|0|ptr:456968|FUBP1; far upstream element (FUSE) binding protein 1; K13210 far upstream element-binding protein (A)	--	[A]	RNA processing and modification	KH domain;; KH domain;; KH domain;; Domain of unknown function (DUF1897);; KH domain	Far upstream element-binding protein 1 GN=FUBP1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: far upstream element-binding protein 1 isoform X4 [Galeopterus variegatus]
ENSG00000162614(NEXN)	--	1.486224591	109	2.703925249	197	2.761313972	172	4.390808937	345	3.36056694	218	3.62968868	263	1.32E-11	1.617935038	up	0.959522826	0.123802249	normal	0.300019729	0.600065299	normal	0.049983048	0.766978234	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain	Nexilin OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: nexilin isoform X1 [Lipotes vexillifer]
ENSG00000162616(DNAJB4)	--	5.251618903	212	8.998987	363	9.93518	387	12.14322664	481	14.11897029	570	11.066573	444	5.66E-07	1.145483205	up	0.079549152	0.627463302	normal	0.949698747	0.189243762	normal	0.043802047	0.615189148	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09510|0|pps:100979528|DNAJB4; DnaJ (Hsp40) homolog, subfamily B, member 4; K09510 DnaJ homolog subfamily B member 4 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain	DnaJ homolog subfamily B member 4 GN=DNAJB4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 4 [Galeopterus variegatus] 
ENSG00000162618(ADGRL4)	--	0	0	0	0	0	0	0.0205101	1	0.275247863	1	0.1025912	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04595|0|hsa:64123|ELTD1, ETL, KPG_003, ADGRL4; EGF, latrophilin and seven transmembrane domain containing 1; K04595 latrophilin and seven transmembrane domain containing 1 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Domain of unknown function (DUF3497);; Latrophilin/CL-1-like GPS domain;; Calcium-binding EGF domain	"EGF, latrophilin and seven transmembrane domain-containing protein 1 (Precursor) GN=ELTD1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: EGF, latrophilin and seven transmembrane domain-containing protein 1 [Orcinus orca]"
ENSG00000162620(LRRIQ3)	--	1.9007839	62	3.449633	75	2.774042948	69	2.184073098	46	0.528702712	34	1.2308062	47	0.941227377	-0.448511338	normal	0.081312009	-1.128131755	normal	0.895089683	-0.547597761	normal	0.141261797	-0.719101896	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine rich repeat	Leucine-rich repeat and IQ domain-containing protein 3 GN=LRRIQ3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and IQ domain-containing protein 3 [Ursus maritimus]
ENSG00000162623(TYW3)	--	6.724664495	398	7.705842	458	7.610814	439	7.122014	407	6.819514137	402	7.6961728	456	0.969743132	0.001422669	normal	0.943186363	-0.208841982	normal	0.969815244	0.046364722	normal	0.878299154	-0.054662637	normal	[S]	Function unknown	--	K15450|1.09167e-179|pps:100989797|TYW3; tRNA-yW synthesizing protein 3 homolog (S. cerevisiae); K15450 tRNA wybutosine-synthesizing protein 3 [EC:2.1.1.282] (A)	--	[S]	Function unknown	Methyltransferase TYW3	tRNA wybutosine-synthesizing protein 3 homolog GN=TYW3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: tRNA wybutosine-synthesizing protein 3 homolog isoform X1 [Galeopterus variegatus]
ENSG00000162624(LHX8)	--	0	0	0	0	0	0	0.365227379	16	0.644489807	28	0.444465725	19	--	--	--	2.99E-05	4.276384366	up	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09375|0|pps:100988677|LHX8; LIM homeobox 8; K09375 LIM homeobox protein 6/8 (A)	--	[R]	General function prediction only	LIM domain;; Homeobox domain;; Homeobox KN domain	LIM/homeobox protein Lhx8 GN=LHX8 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LIM/homeobox protein Lhx8 isoform X4 [Bos taurus] 
ENSG00000162627(SNX7)	--	11.78599263	360	14.45836629	437	13.76551112	416	19.18943222	592	18.21177415	555	17.44731795	533	0.023368129	0.684468635	normal	0.869802768	0.322435772	normal	0.835290951	0.348139759	normal	0.022141486	0.448405976	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17921|0|hsa:51375|SNX7; sorting nexin 7; K17921 sorting nexin-7/30 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PX domain	Sorting nexin-7 GN=SNX7 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-7 [Oryctolagus cuniculus]
ENSG00000162630(B3GALT2)	--	0	0	0.093627	5	0.0186744	0	0.0184169	1	0.0179426	0	0.0366589	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K07820|0|ptr:469624|B3GALT2; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2; K07820 beta-1,3-galactosyltransferase 2 [EC:2.4.1.-] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"Beta-1,3-galactosyltransferase 2 GN=B3GALT2 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyltransferase 2 [Canis lupus familiaris]"
ENSG00000162636(FAM102B)	--	4.705403015	404	5.21933	444	4.432993	374	6.623731867	577	6.026978002	519	5.29353793	456	0.468650096	0.481843318	normal	0.945999479	0.203107931	normal	0.9108003	0.276689331	normal	0.136173434	0.322747005	normal	--	--	--	--	--	--	--	N-terminal C2 in EEIG1 and EHBP1 proteins	Protein FAM102B GN=FAM102B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM102B [Tupaia chinensis]
ENSG00000162639(HENMT1)	--	4.062643099	119	3.031275101	89	4.4157224	125	3.837955024	112	5.301877299	150	5.105586031	143	0.966079783	-0.116741067	normal	0.274330178	0.722108594	normal	0.957318388	0.18371615	normal	0.555814067	0.262394893	normal	--	--	--	--	--	[S]	Function unknown	Methyltransferase domain	Small RNA 2'-O-methyltransferase GN=HENMT1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: small RNA 2'-O-methyltransferase isoform X1 [Galeopterus variegatus]
ENSG00000162642(C1orf52)	--	10.01163259	179	8.666729	168	9.835167	199	11.14320488	226	10.36861852	223	9.997203	209	0.910633452	0.303210513	normal	0.846443988	0.384145727	normal	0.965548187	0.061983404	normal	0.478197495	0.248041152	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4660)	UPF0690 protein C1orf52 GN=C1orf52 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0690 protein C1orf52 homolog [Mustela putorius furo]
ENSG00000162643(WDR63)	--	0.372607868	23	1.93158069	48	0.738295909	44	0.685135119	23	0.233902	14	0.51015	32	0.987850059	-0.028901613	normal	0.014342364	-1.694430252	normal	0.961414909	-0.449532534	normal	0.256451241	-0.756986965	normal	--	--	--	--	--	[Z]	Cytoskeleton	"WD domain, G-beta repeat"	WD repeat-containing protein 63 GN=WDR63 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: WD repeat-containing protein 63 [Ceratotherium simum simum]
ENSG00000162645(GBP2)	--	2.591954	125	2.124654	102	2.142835	105	7.349693	353	7.58895	362	6.506374	311	1.06E-09	1.455802453	up	5.83E-14	1.790976605	up	3.37E-10	1.544680515	up	7.78E-13	1.606165564	up	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	"Guanylate-binding protein, C-terminal domain;; Guanylate-binding protein, N-terminal domain"	Interferon-induced guanylate-binding protein 2 (Precursor) GN=GBP2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: interferon-induced guanylate-binding protein 2 isoform X1 [Equus caballus] 
ENSG00000162650(ATXN7L2)	--	0.682846474	37	1.145649042	59	0.38410629	20	0.785203309	42	0.52968866	28	0.73051546	39	0.980455456	0.146326406	normal	0.32429901	-1.056522242	normal	0.838946218	0.905353346	normal	0.928816517	-0.112819469	normal	--	--	--	K11318|0|hsa:127002|ATXN7L2; ataxin 7-like 2; K11318 ataxin-7 (A)	--	--	--	"SCA7, zinc-binding domain"	Ataxin-7-like protein 2 GN=ATXN7L2 OS=Homo sapiens (Human) PE=2 SV=1	B	Chromatin structure and dynamics	PREDICTED: ataxin-7-like protein 2 isoform 3 [Dasypus novemcinctus]
ENSG00000162654(GBP4)	--	0.0300296	3	0.00997848	1	0	0	0.00996045	1	0.0680665	6	0.0198921	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	"Guanylate-binding protein, C-terminal domain;; Guanylate-binding protein, N-terminal domain"	Guanylate-binding protein 4 GN=GBP4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: guanylate-binding protein 4-like [Galeopterus variegatus]
ENSG00000162664(ZNF326)	--	17.589118	835	18.32487591	876	19.95700949	934	18.96733706	909	14.312544	741	20.62663955	972	0.974451283	0.091510427	normal	0.927066868	-0.262390701	normal	0.978138533	0.049164285	normal	0.910252232	-0.033528378	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	K13204|0|pps:100971268|ZNF326; zinc finger protein 326; K13204 zinc finger protein 326 (A)	--	--	--	A-kinase anchoring protein 95 (AKAP95)	DBIRD complex subunit ZNF326 GN=ZNF326 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DBIRD complex subunit ZNF326-like isoform X1 [Mustela putorius furo] 
ENSG00000162669(HFM1)	--	0.081340674	7	0.750190499	5	0	0	0.057259516	3	0.08676985	4	0.012688245	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K15271|0|hsa:164045|HFM1, MER3, POF9, SEC63D1, Si-11, Si-11-6, helicase; HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) (EC:3.6.4.12); K15271 ATP-dependent DNA helicase HFM1/MER3 [EC:3.6.4.12] (A)"	--	[A]	RNA processing and modification	"Sec63 Brl domain;; DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Probable ATP-dependent DNA helicase HFM1 GN=HFM1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	"PREDICTED: probable ATP-dependent DNA helicase HFM1, partial [Galeopterus variegatus]"
ENSG00000162670(BRINP3)	--	0	0	0	0	0	0	0	0	0.037522544	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MAC/Perforin domain	BMP/retinoic acid-inducible neural-specific protein 3 (Precursor) GN=BRINP3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM5C-like isoform X1 [Mustela putorius furo] 
ENSG00000162676(GFI1)	--	0.019947107	1	0.019757048	1	0.019343493	0	0.080040207	4	0.077231433	3	0.137981292	7	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09223|0|hsa:2672|GFI1, GFI-1, GFI1A, SCN2, ZNF163; growth factor independent 1 transcription repressor; K09223 growth factor independent 1 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein Gfi-1 GN=GFI1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	zinc finger protein Gfi-1 [Canis lupus familiaris] 
ENSG00000162687(KCNT2)	--	0.256600084	23	0.228150112	21	0.21749197	17	0.312804632	33	0.587904164	52	0.75288533	64	0.973179985	0.464011794	normal	0.214118751	1.228753457	normal	0.000522715	1.815425249	up	0.015132223	1.268768159	normal	[P]	Inorganic ion transport and metabolism	Biological Process: potassium ion transport (GO:0006813);; Cellular Component: membrane (GO:0016020);; 	"K04947|0|ptr:457600|KCNT2; potassium channel, subfamily T, member 2; K04947 potassium channel subfamily T member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Calcium-activated BK potassium channel alpha subunit;; Ion channel	Potassium channel subfamily T member 2 GN=KCNT2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily T member 2 [Tupaia chinensis]
ENSG00000162688(AGL)	--	5.92717901	716	6.387697259	771	5.756985905	680	4.880024878	594	6.011411834	722	4.667415894	555	0.893192324	-0.299621779	normal	0.969527212	-0.115923555	normal	0.892141311	-0.300597103	normal	0.261005815	-0.233320825	normal	[G]	Carbohydrate transport and metabolism	--	"K01196|0|hsa:178|AGL, GDE; amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase (EC:2.4.1.25 3.2.1.33); K01196 glycogen debranching enzyme [EC:2.4.1.25 3.2.1.33] (A)"	Starch and sucrose metabolism (ko00500)	[G]	Carbohydrate transport and metabolism	"glucanotransferase domain of human glycogen debranching enzyme;; Amylo-alpha-1,6-glucosidase;; central domain of human glycogen debranching enzyme;; N-terminal domain from the human glycogen debranching enzyme;; Alpha amylase, catalytic domain"	"Amylo-alpha-1,6-glucosidase GN=AGL OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: glycogen debranching enzyme [Tupaia chinensis]
ENSG00000162692(VCAM1)	--	0.050677714	3	0	0	0.040888561	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell adhesion (GO:0007155);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06527|0|hsa:7412|VCAM1, CD106, INCAM-100; vascular cell adhesion molecule 1; K06527 vascular cell adhesion molecule 1 (A)"	NF-kappa B signaling pathway (ko04064);; Cell adhesion molecules (CAMs) (ko04514);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; African trypanosomiasis (ko05143);; Malaria (ko05144);; HTLV-I infection (ko05166)	--	--	"Immunoglobulin I-set domain;; Immunoglobulin C2-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Intercellular adhesion molecule (ICAM), N-terminal domain;; Immunoglobulin C1-set domain"	Vascular cell adhesion protein 1 (Precursor) GN=VCAM1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	vascular cell adhesion protein 1 precursor [Oryctolagus cuniculus] 
ENSG00000162694(EXTL2)	--	9.66031	427	7.410011419	332	9.38451	404	7.3061572	331	8.143663	365	6.627430014	305	0.75840056	-0.396611172	normal	0.961525491	0.114787874	normal	0.732289136	-0.412056246	normal	0.367333054	-0.237597145	normal	--	--	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K02369|0|hsa:2135|EXTL2, EXTR2; exostosin-like glycosyltransferase 2 (EC:2.4.1.223); K02369 alpha-1,4-N-acetylglucosaminyltransferase EXTL2 [EC:2.4.1.223] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[GMW]	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Extracellular structures	Glycosyl transferase family 64 domain	Processed exostosin-like 2 GN=EXTL2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: exostosin-like 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000162695(SLC30A7)	--	4.97723	453	5.351078	433	4.130271957	380	7.083371	636	8.22637	669	6.512848	560	0.545510398	0.457368808	normal	0.099183225	0.604501683	normal	0.237595873	0.549324225	normal	0.003293614	0.53713972	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14692|0|hsa:148867|SLC30A7, ZNT7, ZnT-7, ZnTL2; solute carrier family 30 (zinc transporter), member 7; K14692 solute carrier family 30 (zinc transporter), member 5/7 (A)"	--	[P]	Inorganic ion transport and metabolism	Cation efflux family	Zinc transporter 7 GN=SLC30A7 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter 7 [Ceratotherium simum simum]
ENSG00000162702(ZNF281)	--	22.97087073	1928	31.69525688	2570	25.8216	2076	16.21224556	1348	18.84149467	1540	21.13717256	1752	0.16524265	-0.546592782	normal	0.001222157	-0.759680405	normal	0.953712574	-0.252894319	normal	0.020739717	-0.523239294	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 281 GN=ZNF281 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 281 [Galeopterus variegatus]
ENSG00000162704(ARPC5)	--	103.7810507	3445	119.1243808	3785	113.1015708	3653	163.8544009	5376	134.0782007	4387	130.6168908	4181	0.058055796	0.610977134	normal	0.983512529	0.191443749	normal	0.983757693	0.186402667	normal	0.039965527	0.335554943	normal	--	--	Cellular Component: Arp2/3 protein complex (GO:0005885);; Cellular Component: actin cytoskeleton (GO:0015629);; Biological Process: regulation of actin filament polymerization (GO:0030833);; Biological Process: Arp2/3 complex-mediated actin nucleation (GO:0034314);; 	"K05754|2.84977e-109|nle:100581707|ARPC5; actin related protein 2/3 complex, subunit 5, 16kDa; K05754 actin related protein 2/3 complex, subunit 5 (A)"	Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	ARP2/3 complex 16 kDa subunit (p16-Arc)	Actin-related protein 2/3 complex subunit 5 GN=ARPC5 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: actin-related protein 2/3 complex subunit 5 isoform X1 [Sus scrofa]
ENSG00000162706(CADM3)	--	0.056750588	3	0.0652249	5	0.064439051	4	0.013348395	1	0.038938743	2	0.10336232	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06780|0|ptr:457426|CADM3; cell adhesion molecule 3; K06780 cell adhesion molecule 3 (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin C1-set domain	Cell adhesion molecule 3 (Precursor) GN=UNQ225/PRO258 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cell adhesion molecule 3 [Oryctolagus cuniculus]
ENSG00000162711(NLRP3)	--	0	0	0	0	0	0	0.015424875	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12800|0|hsa:114548|NLRP3, AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCAS1, FCU, MWS, NALP3, PYPAF1; NLR family, pyrin domain containing 3; K12800 NACHT, LRR and PYD domains-containing protein 3 (A)"	NOD-like receptor signaling pathway (ko04621);; Pertussis (ko05133);; Influenza A (ko05164)	--	--	NACHT domain;; PAAD/DAPIN/Pyrin domain;; Fish-specific NACHT associated domain;; Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	"NACHT, LRR and PYD domains-containing protein 3 GN=NLRP3 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: NACHT, LRR and PYD domains-containing protein 3 isoform X3 [Galeopterus variegatus]"
ENSG00000162714(ZNF496)	--	9.898890679	1087	10.29167732	1068	8.301882203	864	9.101560405	963	9.619626542	1049	8.74563751	978	0.957180354	-0.205267996	normal	0.978942927	-0.047256008	normal	0.964451912	0.170231491	normal	0.903805973	-0.035400323	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:84838|ZNF496, NIZP1, ZFP496, ZKSCAN17, ZSCAN49; zinc finger protein 496; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 496 GN=ZNF496 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	zinc finger protein 496 [Ovis aries] 
ENSG00000162723(SLAMF9)	--	0	0	0	0	0	0	0.3467474	5	0.099602577	1	0.078383029	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	SLAM family member 9 (Precursor) GN=SLAMF9 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: SLAM family member 9 [Physeter catodon]
ENSG00000162728(KCNJ9)	--	0	0	0.00994747	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05002|0|pps:100969260|KCNJ9; potassium inwardly-rectifying channel, subfamily J, member 9; K05002 potassium inwardly-rectifying channel subfamily J member 9 (A)"	Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Estrogen signaling pathway (ko04915);; Oxytocin signaling pathway (ko04921);; Morphine addiction (ko05032)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	G protein-activated inward rectifier potassium channel 3 GN=KCNJ9 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	"TPA: potassium inwardly-rectifying channel, subfamily J, member 9 isoform 2 [Bos taurus]"
ENSG00000162729(IGSF8)	--	13.65499539	567	9.113624725	399	11.72191739	512	9.713120798	401	10.49505851	431	9.268607953	389	0.295958696	-0.528865151	normal	0.965483245	0.089545967	normal	0.730265414	-0.403294032	normal	0.208685463	-0.296636781	normal	--	--	--	"K06730|0|hsa:93185|IGSF8, CD316, CD81P3, EWI-2, EWI2, KCT-4, LIR-D1, PGRL; immunoglobulin superfamily, member 8; K06730 immunoglobulin superfamily, member 8 (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Immunoglobulin superfamily member 8 (Precursor) GN=IGSF8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 8 [Oryctolagus cuniculus]
ENSG00000162733(DDR2)	--	0.06584695	8	0.081289098	15	0.143283441	12	0.089710231	9	0.056631781	5	0.056949769	6	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05125|0|hsa:4921|DDR2, MIG20a, NTRKR3, TKT, TYRO10; discoidin domain receptor tyrosine kinase 2 (EC:2.7.10.1); K05125 discoidin domain receptor family member 2 [EC:2.7.10.1] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; F5/8 type C domain	Discoidin domain-containing receptor 2 (Precursor) GN=DDR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: discoidin domain-containing receptor 2 isoform X1 [Camelus bactrianus] 
ENSG00000162734(PEA15)	--	43.30001047	2188	48.99758387	2514	51.07012943	2647	90.07818967	4597	70.20292291	3568	71.80607698	3774	4.29E-08	1.039733003	up	0.497279859	0.483459153	normal	0.378952607	0.503202796	normal	6.93E-05	0.678356616	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Death effector domain	Astrocytic phosphoprotein PEA-15 GN=PEA15 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: astrocytic phosphoprotein PEA-15 isoform 1 [Orcinus orca] 
ENSG00000162736(NCSTN)	--	33.04903754	1609	27.25141503	1434	28.81220101	1452	37.843314	1923	35.49813374	1776	39.06583393	1929	0.961820701	0.226164429	normal	0.930070404	0.286887696	normal	0.743775373	0.401156588	normal	0.063315773	0.303028126	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein processing (GO:0016485);; 	K06171|0|ptr:457435|NCSTN; nicastrin; K06171 nicastrin (A)	Notch signaling pathway (ko04330);; Alzheimer's disease (ko05010)	[TO]	"Signal transduction mechanisms;; Posttranslational modification, protein turnover, chaperones"	Nicastrin	Nicastrin (Precursor) GN=NCSTN OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: nicastrin [Galeopterus variegatus]
ENSG00000162738(VANGL2)	--	2.114497	179	1.734225	148	1.773171	151	2.9129	245	4.67886	391	2.065553	177	0.790209262	0.418905763	normal	6.13E-09	1.371196829	up	0.947570622	0.218882687	normal	0.234686975	0.744524415	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: integral component of membrane (GO:0016021);; 	K04510|0|ngi:103740220|Vangl2; VANGL planar cell polarity protein 2; K04510 vang-like (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Strabismus protein	Vang-like protein 2 GN=VANGL2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: vang-like protein 2 isoform X1 [Leptonychotes weddellii]
ENSG00000162745(OLFML2B)	--	0.16157837	8	0.181994	12	0.138987993	5	0.2393867	16	0.243908161	16	0.167352804	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Olfactomedin-like domain	Olfactomedin-like protein 2B (Precursor) GN=OLFML2B OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: olfactomedin-like protein 2B isoform X1 [Orycteropus afer afer]
ENSG00000162746(FCRLB)	--	0.307815074	9	0.40588369	15	0.702194292	21	0.453949839	16	0.555010945	23	0.540736106	19	--	--	--	0.97792261	0.550180788	normal	0.988239312	-0.141931572	normal	--	--	--	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin domain	Fc receptor-like B (Precursor) GN=FCRLB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: Fc receptor-like B isoform X1 [Oryctolagus cuniculus]
ENSG00000162753(SLC9C2)	--	0	0	0	0	0.0459696	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14726|0|hsa:284525|SLC9C2, SLC9A11; solute carrier family 9, member C2 (putative); K14726 solute carrier family 9 (sodium/hydrogen exchanger), member 10/11 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Sodium/hydrogen exchanger family;; Cyclic nucleotide-binding domain	Sodium/hydrogen exchanger 11 GN=SLC9C2 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 11 [Balaenoptera acutorostrata scammoni]
ENSG00000162755(KLHDC9)	--	1.53032	30	0.886157174	18	1.418491085	27	1.366599355	25	1.93509814	36	1.091372818	23	0.982434387	-0.278233345	normal	0.853441877	0.922816048	normal	0.984652679	-0.225894447	normal	0.898038535	0.142624744	normal	--	--	--	--	--	[R]	General function prediction only	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Kelch motif"	Kelch domain-containing protein 9 GN=KLHDC9 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: kelch domain-containing protein 9 isoform X1 [Galeopterus variegatus]
ENSG00000162757(C1orf74)	--	2.19147	170	1.68636	132	1.78823	138	1.90954	150	1.34855	104	1.7607	137	0.950085875	-0.209388163	normal	0.909110294	-0.360713162	normal	0.96821685	-0.018579468	normal	0.674086689	-0.192079407	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4504)	UPF0739 protein C1orf74 GN=C1orf74 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0739 protein C1orf74 homolog [Ceratotherium simum simum]
ENSG00000162769(FLVCR1)	--	6.398999667	558	8.395277734	825	8.047896702	722	6.870038489	652	5.875509563	572	7.484014218	733	0.952059937	0.193281885	normal	0.204262786	-0.548590576	normal	0.975857422	0.013494866	normal	0.734432459	-0.126075683	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08220|0|hsa:28982|FLVCR1, AXPC1, FLVCR, MFSD7B, PCA, PCARP; feline leukemia virus subgroup C cellular receptor 1; K08220 MFS transporter, FLVCR family, feline leukemia virus subgroup C receptor-related protein (A)"	--	[R]	General function prediction only	Major Facilitator Superfamily	Feline leukemia virus subgroup C receptor-related protein 1 GN=FLVCR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: feline leukemia virus subgroup C receptor-related protein 1 isoform X1 [Equus caballus] 
ENSG00000162772(ATF3)	--	1.184461105	46	1.693525569	63	1.368549722	43	1.226975474	48	1.931696344	56	2.862943943	112	0.979851363	0.029600431	normal	0.970492591	-0.186597473	normal	0.000651845	1.34247755	up	0.58270226	0.487846754	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09032|1.62502e-100|pps:100971096|ATF3; activating transcription factor 3; K09032 activating transcription factor 3 (A)	HTLV-I infection (ko05166)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Cyclic AMP-dependent transcription factor ATF-3 GN=ATF3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cyclic AMP-dependent transcription factor ATF-3 isoform X1 [Ochotona princeps] 
ENSG00000162775(RBM15)	--	1.193123054	76	1.39869551	92	1.732056981	114	2.4794621	158	2.06163485	131	1.773088	115	0.007321698	1.010560911	up	0.821756538	0.481767241	normal	0.969628389	0.004252429	normal	0.189340215	0.497014766	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K13190|0|mcf:102131306|RBM15; RNA binding motif protein 15; K13190 RNA-binding protein 15 (A)	--	[R]	General function prediction only	"SPOC domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Putative RNA-binding protein 15 GN=RBM15 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: putative RNA-binding protein 15 isoform X1 [Leptonychotes weddellii]
ENSG00000162777(DENND2D)	--	0.350839214	12	0.13291078	5	0.323033747	10	0.774384886	26	1.374475854	46	0.6652	23	0.91932654	0.99626999	normal	1.10E-05	2.848468206	up	0.917631424	1.082839525	normal	0.012003014	1.794293564	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; uDENN domain;; dDENN domain	DENN domain-containing protein 2D GN=DENND2D OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 2D isoform X1 [Orycteropus afer afer]
ENSG00000162779(AXDND1)	--	0.228765815	3	0	0	0.22137201	1	0.219786942	5	0.014030673	0	0.357792686	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Axonemal dynein light chain	Axonemal dynein light chain domain-containing protein 1 GN=AXDND1 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: axonemal dynein light chain domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000162782(TDRD5)	--	0.144500592	9	0.191855799	11	0.2456986	14	0.029734629	2	0.058254521	3	0.117269575	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18407|0|hsa:163589|TDRD5, TUDOR3; tudor domain containing 5; K18407 tudor domain-containing protein 5 (A)"	--	[K]	Transcription	OST-HTH/LOTUS domain;; Tudor domain	Tudor domain-containing protein 5 GN=TDRD5 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: tudor domain-containing protein 5 isoform 1 [Odobenus rosmarus divergens]
ENSG00000162783(IER5)	--	42.5395	2787	38.2635	2558	38.8777	2588	41.7477	2779	41.0768	2698	36.6853	2423	0.989416189	-0.034960131	normal	0.988229565	0.055415625	normal	0.986189067	-0.103272274	normal	0.923805752	-0.027632272	normal	--	--	--	--	--	--	--	Immediate early response protein (IER)	Immediate early response gene 5 protein GN=IER5 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: immediate early response gene 5 protein [Bos taurus] 
ENSG00000162804(SNED1)	--	0.789878013	89	0.602109777	102	0.51431836	85	0.353779074	38	0.467556137	56	0.256713058	43	0.012244008	-1.225286453	normal	0.212058477	-0.868848238	normal	0.182522305	-0.966779524	normal	0.010917761	-1.031407445	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: cell-matrix adhesion (GO:0007160);; 	--	--	[T]	Signal transduction mechanisms	EGF-like domain;; Fibronectin type III domain;; Nidogen-like;; EGF-like domain;; Human growth factor-like EGF;; Calcium-binding EGF domain	"Sushi, nidogen and EGF-like domain-containing protein 1 (Precursor) GN=SNED1 OS=Homo sapiens (Human) PE=2 SV=2"	W	Extracellular structures	"PREDICTED: sushi, nidogen and EGF-like domain-containing protein 1 [Ceratotherium simum simum]"
ENSG00000162813(BPNT1)	--	15.85865297	584	13.82204403	438	14.18228737	514	17.96637855	641	19.83531465	691	21.36735631	728	0.968917611	0.10326436	normal	0.05667776	0.634569866	normal	0.396433674	0.492654776	normal	0.03108447	0.402743681	normal	[G]	Carbohydrate transport and metabolism	Biological Process: phosphatidylinositol phosphorylation (GO:0046854);; 	"K01082|0|pps:100992577|BPNT1; 3'(2'), 5'-bisphosphate nucleotidase 1; K01082 3'(2'), 5'-bisphosphate nucleotidase [EC:3.1.3.7] (A)"	Sulfur metabolism (ko00920)	[F]	Nucleotide transport and metabolism	Inositol monophosphatase family	"3'(2'),5'-bisphosphate nucleotidase 1 GN=BPNT1 OS=Homo sapiens (Human) PE=1 SV=1"	F	Nucleotide transport and metabolism	"PREDICTED: 3'(2'),5'-bisphosphate nucleotidase 1 isoform X2 [Loxodonta africana]"
ENSG00000162814(SPATA17)	--	0.278832809	14	0.165889096	3	0.244665446	11	4.883236122	87	6.1557822	123	4.6326544	94	1.02E-08	2.48157291	up	0	4.768583011	up	1.13E-11	2.92461602	up	8.54E-15	3.420485581	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	IQ calmodulin-binding motif	Spermatogenesis-associated protein 17 GN=SPATA17 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: spermatogenesis-associated protein 17 [Camelus dromedarius]
ENSG00000162817(C1orf115)	--	6.39746	444	5.16509	370	5.4483	386	5.48768	383	6.26815	431	5.61507	389	0.929668294	-0.2431406	normal	0.946135232	0.197985701	normal	0.969538108	0.002866678	normal	0.971083755	-0.01753589	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf115 GN=C1orf115 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf115 homolog [Orcinus orca] 
ENSG00000162819(BROX)	--	18.42420145	1130	21.38675119	1299	20.03152026	1206	18.30246842	1122	18.20980716	1097	24.49904814	1388	0.980315003	-0.041026379	normal	0.935271569	-0.264928374	normal	0.964846655	0.194258984	normal	0.911558094	-0.031771876	normal	--	--	--	--	--	--	--	BRO1-like domain	BRO1 domain-containing protein BROX (Precursor) GN=BROX OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: BRO1 domain-containing protein BROX [Odobenus rosmarus divergens]
ENSG00000162825(NBPF20)	--	1.275420364	140	1.213463898	137	2.022396011	195	1.696992942	178	1.452844773	149	1.18557301	134	0.916982964	0.312570084	normal	0.963712015	0.098665354	normal	0.584273551	-0.544409121	normal	0.922328036	-0.055455716	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220);; Euplotes octocarinatus mating pheromone protein	Neuroblastoma breakpoint family member 14 GN=NBPF14 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"TPA: neuroblastoma breakpoint family, member 3-like [Bos taurus]"
ENSG00000162836(ACP6)	--	5.357289926	304	5.652183069	310	5.630963326	312	7.925964169	481	11.64996349	554	6.712182312	417	0.088428679	0.628587717	normal	0.002025383	0.813184363	normal	0.737633054	0.408491528	normal	0.001447971	0.627501601	normal	--	--	Molecular Function: acid phosphatase activity (GO:0003993);; 	"K14395|0|hsa:51205|ACP6, ACPL1, LPAP, PACPL1; acid phosphatase 6, lysophosphatidic (EC:3.1.3.2); K14395 lysophosphatidic acid phosphatase type 6 [EC:3.1.3.2] (A)"	Riboflavin metabolism (ko00740)	[I]	Lipid transport and metabolism	Histidine phosphatase superfamily (branch 2)	Lysophosphatidic acid phosphatase type 6 (Precursor) GN=ACP6 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: lysophosphatidic acid phosphatase type 6 [Orycteropus afer afer]
ENSG00000162849(KIF26B)	--	0.01252151	3	0	0	0	0	0.05016218	13	0.030018188	6	0.012383403	3	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10404|0|hsa:55083|KIF26B; kinesin family member 26B; K10404 kinesin family member 26 (A)	--	--	--	Kinesin motor domain	Kinesin-like protein KIF26B GN=KIF26B OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: kinesin-like protein KIF26B [Equus caballus]
ENSG00000162851(TFB2M)	--	16.985685	486	20.42804	588	20.06851	568	20.0077077	582	20.746077	593	22.06393	632	0.937901138	0.228569586	normal	0.97282852	-0.00918708	normal	0.963077957	0.145375095	normal	0.661578003	0.117262111	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K17653|0|hsa:64216|TFB2M, Hkp1, mtTFB2; transcription factor B2, mitochondrial; K17653 dimethyladenosine transferase 2, mitochondrial [EC:2.1.1.-] (A)"	--	[A]	RNA processing and modification	Ribosomal RNA adenine dimethylase	"Dimethyladenosine transferase 2, mitochondrial (Precursor) GN=TFB2M OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: dimethyladenosine transferase 2, mitochondrial [Tupaia chinensis]"
ENSG00000162852(CNST)	--	5.166592355	461	5.585801436	478	4.902389858	407	5.570503	490	5.68241691	502	5.967954	525	0.969769602	0.056998469	normal	0.969761226	0.049098606	normal	0.820648062	0.357823539	normal	0.573295351	0.151306943	normal	--	--	Cellular Component: trans-Golgi network (GO:0005802);; Biological Process: positive regulation of Golgi to plasma membrane protein transport (GO:0042998);; Molecular Function: connexin binding (GO:0071253);; 	"K17581|0|nle:100580278|CNST; consortin, connexin sorting protein; K17581 consortin (A)"	--	--	--	Consortin C-terminus	Consortin GN=CNST OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: consortin [Orcinus orca]
ENSG00000162869(PPP1R21)	--	7.210977	458	5.922677442	386	6.383002709	413	5.880927432	385	7.023705025	456	4.84093878	314	0.90780669	-0.280294261	normal	0.939769531	0.218219095	normal	0.752075835	-0.401975122	normal	0.62400934	-0.143704615	normal	--	--	--	"K17562|0|pps:100987706|PPP1R21; protein phosphatase 1, regulatory subunit 21; K17562 protein phosphatase 1 regulatory subunit 21 (A)"	--	[S]	Function unknown	Predicted coiled-coil domain-containing protein;; Predicted coiled-coil domain-containing protein	Protein phosphatase 1 regulatory subunit 21 GN=PPP1R21 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 21 [Panthera tigris altaica]
ENSG00000162873(KLHDC8A)	--	0.330245152	16	0.233767459	4	0.94348789	15	0.246736478	13	0.386108403	13	0.138221442	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Kelch domain-containing protein 8A GN=KLHDC8A OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: kelch domain-containing protein 8A [Sus scrofa]
ENSG00000162878(PKDCC)	--	8.65957041	420	5.699883547	295	5.35177119	262	3.20823096	152	4.044718144	185	3.68416457	171	4.35E-11	-1.487697825	down	0.085838112	-0.69010626	normal	0.246877547	-0.619402416	normal	0.007405051	-0.964746943	normal	--	--	--	"K17548|0|hsa:91461|PKDCC, SGK493, Vlk; protein kinase domain containing, cytoplasmic (EC:2.7.10.2); K17548 protein kinase domain-containing protein, cytoplasmic (A)"	--	[T]	Signal transduction mechanisms	Protein-kinase domain of FAM69;; Protein kinase domain	Extracellular tyrosine-protein kinase PKDCC {ECO:0000305} (Precursor) OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	"PREDICTED: protein kinase domain-containing protein, cytoplasmic [Odobenus rosmarus divergens]"
ENSG00000162881(OXER1)	--	0.0396205	1	0.116065	3	0.0378436	0	0.117585	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K10043|0|ptr:737078|OXER1; oxoeicosanoid (OXE) receptor 1; K10043 oxoeicosanoid receptor 1 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	Oxoeicosanoid receptor 1 GN=OXER1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: oxoeicosanoid receptor 1 [Panthera tigris altaica]
ENSG00000162885(B3GALNT2)	--	12.429584	819	11.544751	826	12.807115	899	13.588623	917	12.06969	846	11.2495545	798	0.97000631	0.131991933	normal	0.976884409	0.013065687	normal	0.960946595	-0.179902394	normal	0.976503194	-0.011848971	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K09654|0|pon:100443319|B3GALNT2; beta-1,3-N-acetylgalactosaminyltransferase 2; K09654 beta-1,3-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 GN=B3GALNT2 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 2 [Ceratotherium simum simum]"
ENSG00000162889(MAPKAPK2)	--	22.4786794	1350	20.994974	1250	21.0398036	1284	31.5044396	1893	30.85718559	1852	28.55743267	1734	0.532595629	0.456442231	normal	0.191408909	0.545184351	normal	0.657418213	0.424735227	normal	0.001332356	0.474923385	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K04443|0|ptr:744091|MAPKAPK2; mitogen-activated protein kinase-activated protein kinase 2; K04443 mitogen-activated protein kinase-activated protein kinase 2 [EC:2.7.11.1] (A)	MAPK signaling pathway (ko04010);; VEGF signaling pathway (ko04370);; Neurotrophin signaling pathway (ko04722);; Viral carcinogenesis (ko05203)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	MAP kinase-activated protein kinase 2 GN=MAPKAPK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: MAP kinase-activated protein kinase 2 [Ochotona princeps]
ENSG00000162892(IL24)	--	0	0	0	0	0.035458637	0	0.07161412	2	0.035161163	0	0.1113684	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05444|1.27821e-143|hsa:11009|IL24, C49A, FISP, IL10B, MDA7, MOB5, ST16; interleukin 24; K05444 interleukin 19/20/24 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	--	Interleukin-24 (Precursor) GN=IL24 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-24-like [Galeopterus variegatus] 
ENSG00000162894(FCMR)	--	0.177293778	5	0.1784232	5	0.340231916	8	0.355489941	10	0.413617187	11	0.523409555	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain	Fas apoptotic inhibitory molecule 3 (Precursor) GN=FAIM3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fas apoptotic inhibitory molecule 3 [Ceratotherium simum simum]
ENSG00000162896(PIGR)	--	0	0	0.413317	37	0.264635	23	0	0	0	0	0.0112456	1	--	--	--	8.19E-08	-4.680844359	down	0.004176027	-3.291973349	down	--	--	--	--	--	--	K13073|0|hsa:5284|PIGR; polymeric immunoglobulin receptor; K13073 polymeric immunoglobulin receptor (A)	Intestinal immune network for IgA production (ko04672)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	Secretory component (Precursor) GN=PIGR OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: polymeric immunoglobulin receptor [Felis catus]
ENSG00000162909(CAPN2)	--	122.26424	8874	137.20238	10045	140.78647	10340	207.66542	15163	160.4357	11619	155.06615	11342	0.002815619	0.741967138	normal	0.992431148	0.188555373	normal	0.99509994	0.125129954	normal	0.098749429	0.359787801	normal	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K03853|0|ptr:457765|CAPN2; calpain 2, (m/II) large subunit; K03853 calpain-2 [EC:3.4.22.53] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Apoptosis (ko04210);; Focal adhesion (ko04510);; Alzheimer's disease (ko05010)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF-hand domain pair"	Calpain-2 catalytic subunit (Precursor) GN=CAPN2 OS=Homo sapiens (Human) PE=1 SV=6	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-2 catalytic subunit [Orycteropus afer afer]
ENSG00000162910(MRPL55)	--	42.20086882	346	45.94831072	368	47.30050982	391	49.17299808	405	49.03110735	384	34.34188721	279	0.947245173	0.195514547	normal	0.967682487	0.039813817	normal	0.505313988	-0.492926968	normal	0.845329298	-0.071189721	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: mitochondrial large ribosomal subunit (GO:0005762);; 	"K17436|3.17916e-68|hsa:128308|MRPL55, AAVG5835, L55nt, MRP-L55, PRO19675; mitochondrial ribosomal protein L55; K17436 large subunit ribosomal protein L55 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal protein L55	"39S ribosomal protein L55, mitochondrial (Precursor) GN=MRPL55 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L55, mitochondrial isoform X1 [Tupaia chinensis] "
ENSG00000162913(C1orf145)	--	0.470165	5	0.566249	6	0.828004	8	0.552871	6	0.541308	5	0.366782	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17531|7.66823e-44|nle:100600096|OBSCN; obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF; K17531 Obscurin-RhoGEF [EC:2.7.11.1] (A)"	--	--	--	Domain of unknown function (DUF4608)	Obscurin GN=OBSCN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	Obscurin [Tupaia chinensis]
ENSG00000162923(WDR26)	--	22.07969578	2432	20.7610356	2226	22.15613551	2279	25.22696723	2705	25.70736265	2823	21.39189434	2324	0.985187873	0.122579653	normal	0.919985223	0.321154838	normal	0.98803482	0.019904622	normal	0.420455992	0.157157545	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	WD repeat-containing protein 26 GN=WDR26 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: WD repeat-containing protein 26 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000162924(REL)	--	5.23109	1030	5.70554	1095	5.118772	986	4.25647	830	4.220689	833	4.24968	837	0.846964722	-0.341724199	normal	0.684070068	-0.415309149	normal	0.939459539	-0.244244391	normal	0.049012387	-0.33675467	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09254|0|ptr:470380|REL; v-rel avian reticuloendotheliosis viral oncogene homolog; K09254 c-Rel proto-oncogene protein (A)	Ras signaling pathway (ko04014);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203)	--	--	Rel homology domain (RHD)	Proto-oncogene c-Rel GN=REL OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: proto-oncogene c-Rel [Ceratotherium simum simum]
ENSG00000162927(PUS10)	--	1.675729141	51	2.161937647	56	2.135079276	62	1.582751384	47	2.200812727	63	1.879699009	62	0.977289287	-0.144143494	normal	0.972615139	0.144810029	normal	0.976161028	-0.008094015	normal	1	0.005325106	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K07583|0|hsa:150962|PUS10, CCDC139, DOBI; pseudouridylate synthase 10; K07583 tRNA pseudouridine synthase 10 [EC:5.4.99.-] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	--	Putative tRNA pseudouridine synthase Pus10 GN=PUS10 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: putative tRNA pseudouridine synthase Pus10 [Odobenus rosmarus divergens]
ENSG00000162928(PEX13)	--	14.42332605	788	14.33774401	819	15.499206	777	12.31105257	668	12.679974	669	12.41254043	624	0.920258457	-0.268610151	normal	0.883745128	-0.312643817	normal	0.867498366	-0.323954951	normal	0.109006295	-0.30323531	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Cellular Component: peroxisome (GO:0005777);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein import into peroxisome matrix, docking (GO:0016560);; "	"K13344|0|hsa:5194|PEX13, NALD, PBD11A, PBD11B, ZWS; peroxisomal biogenesis factor 13; K13344 peroxin-13 (A)"	Peroxisome (ko04146)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Peroxin 13, N-terminal region;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain"	Peroxisomal membrane protein PEX13 GN=PEX13 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein PEX13 [Leptonychotes weddellii]
ENSG00000162929(KIAA1841)	--	8.695638965	669	9.001181818	693	10.13413206	766	6.52531846	511	4.906612547	378	6.070231107	468	0.669064412	-0.418411858	normal	0.000150679	-0.893214159	normal	0.007559207	-0.717296852	normal	7.90E-05	-0.670467843	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF3342)	Uncharacterized protein KIAA1841 GN=KIAA1841 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA1841 homolog [Odobenus rosmarus divergens]
ENSG00000162931(TRIM17)	--	0.363494225	23	0.498476679	27	0.468214083	30	0.031612162	2	0.289482417	17	0.455869607	13	0.018175146	-2.817726917	normal	0.964827958	-0.643083868	normal	0.809287626	-1.126300008	normal	0.038366026	-1.339218757	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12007|0|hsa:51127|TRIM17, RBCC, RNF16, terf; tripartite motif containing 17; K12007 tripartite motif-containing protein 17 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; RING-type zinc-finger;; Ring finger domain"	E3 ubiquitin-protein ligase TRIM17 GN=TRIM17 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM17 isoform X3 [Tupaia chinensis]
ENSG00000162944(RFTN2)	--	0.10964969	10	0.221870833	20	0.110365417	9	0.043792211	4	0.10593844	9	0.09825317	9	--	--	--	0.941104135	-1.052217007	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Raftlin	Raftlin-2 GN=RFTN2 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: raftlin-2 [Ceratotherium simum simum]
ENSG00000162946(DISC1)	--	0.85965103	88	0.765440306	48	1.220973218	83	1.258773531	137	1.540133661	154	0.615564723	69	0.622846094	0.599321674	normal	3.89E-07	1.630174888	up	0.958450974	-0.269414771	normal	0.281210195	0.694843539	normal	--	--	--	K16534|0|ptr:742093|DISC1; disrupted in schizophrenia 1; K16534 disrupted in schizophrenia 1 protein (A)	--	--	--	--	Disrupted in schizophrenia 1 protein GN=DISC1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: disrupted in schizophrenia 1 protein [Equus caballus]
ENSG00000162949(CAPN13)	--	0	0	0	0	0	0	0.0188024	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	K08581|0|hsa:92291|CAPN13; calpain 13; K08581 calpain-13 [EC:3.4.22.-] (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III"	Calpain-13 GN=CAPN13 OS=Homo sapiens (Human) PE=1 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-13 [Tupaia chinensis]
ENSG00000162959(MEMO1)	--	40.0602105	934	47.1355653	1020	45.00871929	994	30.29550909	651	30.35718349	611	29.53145529	637	0.171307997	-0.550506001	normal	0.00227568	-0.759280112	normal	0.02580395	-0.649000064	normal	2.33E-05	-0.655762125	normal	[R]	General function prediction only	--	K06990|0|mcc:706051|protein MEMO1-like; K06990 (A)	--	[R]	General function prediction only	Memo-like protein	Protein MEMO1 GN=MEMO1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein MEMO1 [Canis lupus familiaris]
ENSG00000162961(DPY30)	--	74.60485	687	64.58196	597	68.62873	646	63.09127	603	61.18557	559	55.9137	530	0.94443274	-0.218462377	normal	0.966214949	-0.11600545	normal	0.898654179	-0.293074489	normal	0.343440688	-0.211417517	normal	--	--	--	K14965|1.23364e-65|tup:102471012|DPY30; dpy-30 homolog (C. elegans); K14965 protein dpy-30 (A)	--	[K]	Transcription	Dpy-30 motif	Protein dpy-30 homolog GN=DPY30 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"Protein dpy-30-like protein, partial [Bos mutus]"
ENSG00000162971(TYW5)	--	3.897857	300	3.448035	279	3.927164	301	3.110696	243	3.222553	250	2.605667	211	0.874776418	-0.332939703	normal	0.950275426	-0.178739469	normal	0.49929137	-0.517688696	normal	0.205321542	-0.343395404	normal	--	--	--	K18066|0|ptr:745971|TYW5; tRNA-yW synthesizing protein 5; K18066 tRNA wybutosine-synthesizing protein 5 [EC:1.14.11.42] (A)	--	[BT]	Chromatin structure and dynamics;; Signal transduction mechanisms	Cupin-like domain;; Cupin superfamily protein	tRNA wybutosine-synthesizing protein 5 GN=TYW5 OS=Homo sapiens (Human) PE=1 SV=1	BT	Chromatin structure and dynamics;; Signal transduction mechanisms	PREDICTED: tRNA wybutosine-synthesizing protein 5 [Leptonychotes weddellii]
ENSG00000162972(MAIP1)	--	18.90782261	352	18.56514583	373	20.86047446	401	12.09908421	242	14.27936596	276	11.9877834	258	0.283341725	-0.568389207	normal	0.642884274	-0.453786316	normal	0.093284346	-0.641481681	normal	0.01163152	-0.557851993	normal	--	--	--	--	--	--	--	--	"Uncharacterized protein C2orf47, mitochondrial (Precursor) GN=C2orf47 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: uncharacterized protein C2orf47 homolog, mitochondrial [Pteropus alecto]"
ENSG00000162975(KCNF1)	--	2.38707	94	2.8353	115	2.0545	85	2.23744	89	1.90841	76	1.9947	80	0.969483645	-0.107875234	normal	0.673405814	-0.609063658	normal	0.971159944	-0.094029559	normal	0.577037912	-0.285008576	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04899|0|nle:100584305|KCNF1; potassium voltage-gated channel, subfamily F, member 1; K04899 potassium voltage-gated channel subfamily F member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel;; Polycystin cation channel	Potassium voltage-gated channel subfamily F member 1 GN=KCNF1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily F member 1 [Camelus dromedarius]
ENSG00000162976(PQLC3)	--	38.84558203	978	41.69489147	981	32.392247	820	16.61656302	422	15.72752071	379	19.88689211	452	3.61E-10	-1.240365146	down	2.13E-12	-1.389899893	down	0.000161246	-0.865410499	normal	2.51E-14	-1.170522429	down	--	--	--	--	--	[R]	General function prediction only	PQ loop repeat	PQ-loop repeat-containing protein 3 (Precursor) GN=PQLC3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: PQ-loop repeat-containing protein 3 isoform X1 [Orycteropus afer afer]
ENSG00000162980(ARL5A)	--	20.13030694	1332	19.06510302	1190	23.65558053	1415	15.12676954	984	13.41304568	936	13.463724	771	0.470326029	-0.467066581	normal	0.811179892	-0.367280004	normal	3.42E-05	-0.88299223	normal	0.00012468	-0.570599421	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07949|1.78567e-130|ptr:736445|ARL5A; ADP-ribosylation factor-like 5A; K07949 ADP-ribosylation factor-like protein 5A (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Signal recognition particle receptor beta subunit;; Miro-like protein;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	ADP-ribosylation factor-like protein 5A GN=ARL5A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ADP-ribosylation factor-like protein 5A [Orcinus orca] 
ENSG00000162981(FAM84A)	--	1.051564305	69	0.720087636	49	1.20273055	80	0.136756467	10	0.149727304	12	0.272800554	21	6.78E-08	-2.640611278	down	0.002334662	-1.922269516	down	2.74E-05	-1.864240904	down	2.36E-06	-2.221421575	down	--	--	--	--	--	--	--	Lecithin retinol acyltransferase	Protein FAM84A GN=FAM84A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM84A [Camelus dromedarius]
ENSG00000162989(KCNJ3)	--	0.013428659	1	0.040355411	3	0.040112431	2	0.013309927	1	0	0	0.026493937	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04997|0|ptr:737029|KCNJ3; potassium inwardly-rectifying channel, subfamily J, member 3; K04997 potassium inwardly-rectifying channel subfamily J member 3 (A)"	Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Estrogen signaling pathway (ko04915);; Oxytocin signaling pathway (ko04921);; Morphine addiction (ko05032)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	G protein-activated inward rectifier potassium channel 1 GN=KCNJ3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: G protein-activated inward rectifier potassium channel 1 isoform X2 [Canis lupus familiaris]
ENSG00000162994(CLHC1)	--	2.4339051	50	2.00138668	46	1.774428677	46	1.180647164	25	2.032376	26	2.172551004	47	0.59847749	-0.987097298	normal	0.832276295	-0.808721283	normal	0.979656127	0.022019289	normal	0.361360581	-0.554375534	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin-H-link	Clathrin heavy chain linker domain-containing protein 1 GN=CLHC1 OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: clathrin heavy chain linker domain-containing protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000162998(FRZB)	--	0	0	0	0	0	0	0	0	0	0	0.0419744	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Fz domain;; UNC-6/NTR/C345C module	Secreted frizzled-related protein 3 (Precursor) GN=FRZB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: secreted frizzled-related protein 3-like [Tursiops truncatus]
ENSG00000162999(DUSP19)	--	1.04297098	69	1.6542013	88	1.43928286	92	0.426806925	25	0.809628403	41	0.733246427	51	0.007946105	-1.43999671	down	0.050699195	-1.095070305	normal	0.342120896	-0.840605901	normal	0.008361174	-1.108504915	down	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14165|4.0329e-160|pps:100979178|DUSP19; dual specificity phosphatase 19; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 19 GN=DUSP19 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 19 [Orcinus orca] 
ENSG00000163001(CFAP36)	--	26.619486	863	23.80155238	809	30.88149612	852	19.92913834	670	23.36864401	686	19.36733704	635	0.729097791	-0.395230663	normal	0.927616486	-0.258831562	normal	0.617773878	-0.431497804	normal	0.040856181	-0.363491777	normal	--	--	--	--	--	[S]	Function unknown	The ARF-like 2 binding protein BART	Cilia- and flagella-associated protein 36 {ECO:0000312|HGNC:HGNC:30540} GN=CFAP36 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 104 isoform X2 [Panthera tigris altaica]
ENSG00000163002(NUP35)	--	23.87220445	492	21.9599463	484	23.32597	529	13.87581204	310	11.786891	279	13.20728336	295	0.02514969	-0.694463862	normal	0.002730763	-0.812779268	normal	0.000816559	-0.847552753	normal	3.08E-05	-0.788875413	normal	--	--	--	K14313|0|pps:100978624|NUP35; nucleoporin 35kDa; K14313 nuclear pore complex protein Nup53 (A)	RNA transport (ko03013)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Nup53/35/40-type RNA recognition motif;; Nup53/35/40-type RNA recognition motif	Nucleoporin NUP53 GN=NUP35 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nucleoporin NUP53-like isoform X1 [Tupaia chinensis]
ENSG00000163006(CCDC138)	--	4.279696448	272	3.934262416	266	4.4637664	283	2.598124847	197	3.567326597	269	2.25400059	159	0.600737948	-0.492955505	normal	0.966317106	-0.005217136	normal	0.008680537	-0.834037561	normal	0.124526617	-0.414954418	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 138 GN=CCDC138 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 138 isoform 1 [Odobenus rosmarus divergens]
ENSG00000163013(FBXO41)	--	6.3887083	965	5.917794505	920	5.842812301	930	3.953260601	600	4.266957439	590	2.906601306	446	0.005697702	-0.714940336	normal	0.02485299	-0.66097685	normal	2.52E-07	-1.065918204	down	2.05E-07	-0.804962462	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10316|0|hsa:150726|FBXO41, FBX41; F-box protein 41; K10316 F-box protein 41 (A)"	--	[R]	General function prediction only	F-box-like;; F-box domain	F-box only protein 41 GN=FBXO41 OS=Homo sapiens (Human) PE=2 SV=5	R	General function prediction only	PREDICTED: F-box only protein 41 [Ceratotherium simum simum]
ENSG00000163017(ACTG2)	--	0.083674034	2	0.12578604	3	0.117303693	1	0	0	0.081819192	1	0.041565058	1	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	--	"K12315|0|cge:100768744|Actg2; actin, gamma 2, smooth muscle, enteric; K12315 actin, gamma-enteric smooth muscle (A)"	Vascular smooth muscle contraction (ko04270)	[Z]	Cytoskeleton	Actin	"Actin, gamma-enteric smooth muscle (Precursor) GN=ACTG2 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	hypothetical protein CB1_000252031 [Camelus ferus]
ENSG00000163026(WDCP)	--	9.278631187	574	9.339213242	573	11.14192528	641	7.648480314	469	7.691190973	474	7.611723608	463	0.86883981	-0.32134157	normal	0.897450432	-0.294219413	normal	0.47357895	-0.476275471	normal	0.063452411	-0.367762285	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4613)	WD repeat-containing protein C2orf44 GN=C2orf44 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: WD repeat-containing protein C2orf44 homolog isoform X1 [Galeopterus variegatus]
ENSG00000163029(SMC6)	--	17.6025026	1700	18.93112721	1907	18.918891	1923	13.75106984	1378	14.18332782	1414	13.509481	1380	0.879243801	-0.333455649	normal	0.573212041	-0.452530825	normal	0.39883745	-0.486528134	normal	0.004544227	-0.427615521	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	--	--	[L]	"Replication, recombination and repair"	RecF/RecN/SMC N terminal domain;; AAA domain	Structural maintenance of chromosomes protein 6 GN=SMC6 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: structural maintenance of chromosomes protein 6 isoform X1 [Equus przewalskii]
ENSG00000163032(VSNL1)	--	0.030609967	1	0.061239473	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain;; EF-hand domain pair;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Visinin-like protein 1 GN=VSNL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: visinin-like protein 1 isoform X1 [Lipotes vexillifer]
ENSG00000163040(CCDC74A)	--	6.936417065	203	7.78319967	225	6.770784551	206	3.855964398	114	5.308263735	150	4.725125	137	0.020714865	-0.854521197	normal	0.363695529	-0.60140261	normal	0.42990503	-0.591398764	normal	0.016096943	-0.681537908	normal	--	--	--	--	--	--	--	"Coiled coil protein 74, C terminal;; Coiled-coil domain of unknown function"	Coiled-coil domain-containing protein 74A GN=CCDC74A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: coiled-coil domain-containing protein 74B-like, partial [Equus przewalskii]"
ENSG00000163041(H3F3A)	--	323.7511089	4461	346.6468714	4855	343.3297373	4763	403.6430903	5690	407.0228702	5607	406.5794402	5662	0.947347168	0.320131416	normal	0.986816907	0.186277188	normal	0.978816062	0.241079472	normal	0.167109206	0.247322878	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	"K11253|5.5628e-93|xtr:100038101|h3f3b; H3 histone, family 3B (H3.3B); K11253 histone H3 (A)"	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.3 GN=H3F3B OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H3.3-like [Myotis lucifugus]
ENSG00000163050(COQ8A)	--	6.505553	403	6.563828	397	6.764964054	408	5.990034	362	5.046885	311	5.841524786	350	0.950216786	-0.184878225	normal	0.812213565	-0.372045352	normal	0.93622357	-0.228589916	normal	0.302955437	-0.26113341	normal	[R]	General function prediction only	--	"K08869|0|hsa:56997|ADCK3, ARCA2, CABC1, COQ10D4, COQ8, SCAR9; aarF domain containing kinase 3; K08869 aarF domain-containing kinase (A)"	--	[R]	General function prediction only	ABC1 family	"Chaperone activity of bc1 complex-like, mitochondrial (Precursor) GN=ADCK3 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: chaperone activity of bc1 complex-like, mitochondrial [Tupaia chinensis]"
ENSG00000163053(SLC16A14)	--	2.113831088	93	1.731613028	71	3.306304575	92	2.59782451	88	1.148334818	79	1.32693954	46	0.969588761	-0.10871273	normal	0.969632607	0.129981589	normal	0.117279249	-0.98494771	normal	0.598137803	-0.2879355	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08190|0|hsa:151473|SLC16A14, MCT14; solute carrier family 16, member 14; K08190 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 14 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 14 GN=SLC16A14 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 14 [Ceratotherium simum simum]
ENSG00000163064(EN1)	--	1.74717	72	1.24696	52	1.13212	48	1.2113	50	0.718642	30	0.617179	26	0.890307299	-0.542916734	normal	0.804514262	-0.7845654	normal	0.785396455	-0.855647431	normal	0.173708385	-0.722082405	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09319|8.61181e-145|hsa:2019|EN1; engrailed homeobox 1; K09319 homeobox protein engrailed (A)	--	[R]	General function prediction only	Homeobox domain;; Engrailed homeobox C-terminal signature domain	Homeobox protein engrailed-1 GN=EN1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein engrailed-1 [Orycteropus afer afer]
ENSG00000163069(SGCB)	--	22.16978	1386	22.28539	1495	21.54508	1381	22.97542	1438	18.29584	1126	21.27566	1264	0.983248465	0.022279908	normal	0.646294238	-0.429862331	normal	0.975648211	-0.135852741	normal	0.362871703	-0.176719896	normal	--	--	Cellular Component: sarcoglycan complex (GO:0016012);; Cellular Component: integral component of membrane (GO:0016021);; 	"K12566|0|hsa:6443|SGCB, A3b, LGMD2E, SGC; sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); K12566 beta-sarcoglycan (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	--	--	Sarcoglycan complex subunit protein	Beta-sarcoglycan GN=SGCB OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: beta-sarcoglycan [Trichechus manatus latirostris]
ENSG00000163071(SPATA18)	--	3.8278468	277	5.3515372	397	5.469589308	328	4.722885051	325	4.116831974	310	6.27086866	476	0.946191172	0.198703195	normal	0.80481895	-0.37666903	normal	0.342639176	0.526946306	normal	0.814970207	0.128791913	normal	--	--	--	--	--	--	--	--	Mitochondria-eating protein GN=SPATA18 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: mitochondria-eating protein [Vicugna pacos]
ENSG00000163072(NOSTRIN)	--	0.879389838	43	0.895695132	42	1.047712743	51	0.9099926	45	0.985140617	46	1.148507829	58	0.980647974	0.033583094	normal	0.978312466	0.106164577	normal	0.974143336	0.172465825	normal	0.90182151	0.111605795	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; Fes/CIP4, and EFC/F-BAR homology domain"	Nostrin GN=NOSTRIN OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: nostrin isoform X2 [Galeopterus variegatus]
ENSG00000163075(CFAP221)	--	0.140642267	3	0.057828088	1	0.114645647	1	0.116078696	3	0.127679749	3	0.123886371	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cilia- and flagella-associated protein 221 {ECO:0000312|HGNC:HGNC:33720} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: primary ciliary dyskinesia protein 1-like isoform X1 [Tupaia chinensis] 
ENSG00000163082(SGPP2)	--	1.067414	69	0.446178	32	0.345508	22	1.639684	126	1.883058	141	1.495445	118	0.176696799	0.824157756	normal	6.86E-10	2.067494801	up	1.78E-10	2.337699779	up	3.52E-06	1.623844564	up	[I]	Lipid transport and metabolism	--	"K04717|0|hsa:130367|SGPP2, SPP2; sphingosine-1-phosphate phosphatase 2; K04717 sphingosine-1-phosphate phosphotase 2 [EC:3.1.3.-] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[I]	Lipid transport and metabolism	PAP2 superfamily	Sphingosine-1-phosphate phosphatase 2 GN=SGPP2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: sphingosine-1-phosphate phosphatase 2 [Oryctolagus cuniculus]
ENSG00000163083(INHBB)	--	8.75272	586	12.45148	869	7.63203	538	7.23874	500	8.65408	586	5.57435	389	0.92245965	-0.259068514	normal	0.10547701	-0.588626005	normal	0.504960319	-0.47455164	normal	0.312281383	-0.456557785	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04667|0|hsa:3625|INHBB; inhibin, beta B; K04667 inhibin, beta (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain;; TGF-beta propeptide	Inhibin beta B chain (Precursor) GN=INHBB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: inhibin beta B chain [Condylura cristata]
ENSG00000163092(XIRP2)	--	0	0	0	0	0	0	0	0	0	0	0.01667081	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: actin cytoskeleton organization (GO:0030036);; Cellular Component: cell junction (GO:0030054);; 	--	--	--	--	Xin repeat	Xin actin-binding repeat-containing protein 2 GN=XIRP2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: xin actin-binding repeat-containing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000163093(BBS5)	--	4.5525571	248	4.03464954	224	4.3891016	243	2.86673031	156	4.2541177	223	2.4198879	128	0.111143939	-0.694151794	normal	0.965568498	-0.027694192	normal	0.003167602	-0.925035374	normal	0.062467687	-0.517336088	normal	--	--	Cellular Component: BBSome (GO:0034464);; 	K16748|0|pps:100981691|BBS5; Bardet-Biedl syndrome 5; K16748 Bardet-Biedl syndrome 5 protein (A)	--	--	--	Protein of unknown function (DUF1448);; Bacterial PH domain	Bardet-Biedl syndrome 5 protein GN=BBS5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: Bardet-Biedl syndrome 5 protein homolog isoform X1 [Sus scrofa]
ENSG00000163104(SMARCAD1)	--	12.448215	1008	13.36485218	1088	12.7261501	1003	10.93225473	881	11.364892	926	13.39213287	1088	0.948700238	-0.224747188	normal	0.9371021	-0.253638387	normal	0.975372125	0.108907809	normal	0.598137803	-0.118893059	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14439|0|hsa:56916|SMARCAD1, ADERM, ETL1, HEL1; SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 (EC:3.6.4.12); K14439 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 [EC:3.6.4.12] (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[B]	Chromatin structure and dynamics	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase;; CUE domain"	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 GN=SMARCAD1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 isoform X1 [Tupaia chinensis] 
ENSG00000163110(PDLIM5)	--	52.71871706	4295	43.85928129	3765	50.14428925	3779	53.0342789	4769	52.8076985	4940	43.53996353	4150	0.990429778	0.120155586	normal	0.892643995	0.370304414	normal	0.98900678	0.126766951	normal	0.265120902	0.205648038	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain;; PDZ domain (Also known as DHR or GLGF)	PDZ and LIM domain protein 5 GN=PDLIM5 OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: PDZ and LIM domain protein 5 isoform 1 [Trichechus manatus latirostris]
ENSG00000163116(STPG2)	--	0.041068863	1	0	0	0	0	0.040780242	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sperm-tail PG-rich repeat	Sperm-tail PG-rich repeat-containing protein 2 GN=STPG2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: sperm-tail PG-rich repeat-containing protein 2 [Ceratotherium simum simum]
ENSG00000163121(NEURL3)	--	0.356167042	9	0.296532205	7	0.126394758	2	0.496715878	13	0.441873142	10	1.19425008	28	--	--	--	--	--	--	0.001414652	3.06453961	up	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K15689|0|hsa:93082|NEURL3, LINCR; neuralized E3 ubiquitin protein ligase 3; K15689 E3 ubiquitin-protein ligase NEURL3 [EC:6.3.2.19] (A)"	--	[T]	Signal transduction mechanisms	"Neuralized;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase NEURL3 GN=NEURL3 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase NEURL3 [Tupaia chinensis]
ENSG00000163125(RPRD2)	--	8.868119	1017	10.207028	1090	8.760158	979	7.91004	1001	9.436185	1136	9.078539	1115	0.978573776	-0.053628302	normal	0.979820334	0.038156286	normal	0.96463852	0.17911208	normal	0.840739223	0.054617234	normal	--	--	--	--	--	[A]	RNA processing and modification	RNA polymerase II-binding domain.	Regulation of nuclear pre-mRNA domain-containing protein 2 GN=RPRD2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: regulation of nuclear pre-mRNA domain-containing protein 2 isoform X1 [Physeter catodon]
ENSG00000163126(ANKRD23)	--	10.44844574	538	10.821224	526	14.15672543	661	6.973145682	309	6.297701	308	6.0661356	259	0.001184556	-0.827669843	normal	0.003586483	-0.790551511	normal	6.85E-11	-1.3548537	down	2.23E-08	-0.998854604	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 23 GN=ANKRD23 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 23 [Orycteropus afer afer]
ENSG00000163131(CTSS)	--	10.04612105	512	13.28934117	592	10.25282099	557	25.06046134	1340	20.13503111	1067	30.23640102	1541	9.35E-13	1.354579132	up	0.000383276	0.826869594	normal	4.22E-15	1.457344902	up	7.31E-07	1.228196579	up	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	K01368|0|pps:100975000|CTSS; cathepsin S; K01368 cathepsin S [EC:3.4.22.27] (A)	Lysosome (ko04142);; Phagosome (ko04145);; Antigen processing and presentation (ko04612);; Tuberculosis (ko05152)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin propeptide inhibitor domain (I29)	Cathepsin S (Precursor) GN=CTSS OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin S isoform X1 [Galeopterus variegatus] 
ENSG00000163132(MSX1)	--	3.284285853	105	2.549073	78	3.135611005	103	4.798771355	155	4.47411	113	2.471143466	80	0.720046	0.524692771	normal	0.829117101	0.505171355	normal	0.927217658	-0.366737647	normal	0.645570781	0.260166696	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09341|4.87543e-142|ptr:461092|MSX1; msh homeobox 1; K09341 homeobox protein MSX (A)	HTLV-I infection (ko05166)	[R]	General function prediction only	Homeobox domain	Homeobox protein MSX-1 GN=MSX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein MSX-1 [Bos mutus] 
ENSG00000163138(PACRGL)	--	10.02824183	211	8.94603138	206	9.49641219	196	8.581025884	189	9.119123519	208	8.085141397	205	0.951266689	-0.188239758	normal	0.965798301	-0.007433064	normal	0.965837324	0.056055876	normal	0.926651929	-0.047141608	normal	--	--	--	--	--	[S]	Function unknown	Parkin co-regulated protein;; HEAT-like repeat	PACRG-like protein GN=PACRGL OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: PACRG-like protein [Loxodonta africana] 
ENSG00000163141(BNIPL)	--	0.079118117	3	0	0	0.092374042	2	0.09275898	4	0.024320153	0	0.049242209	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K18448|0|pps:100969521|BNIPL; BCL2/adenovirus E1B 19kD interacting protein like; K18448 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (A)	--	--	--	Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2;; Divergent CRAL/TRIO domain;; CRAL/TRIO domain	Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein GN=BNIPL OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein [Ceratotherium simum simum]
ENSG00000163154(TNFAIP8L2)	--	8.472339	189	6.99662277	150	11.261659	208	10.96815093	266	11.375248	258	11.654536	236	0.698578026	0.459048965	normal	0.048345566	0.755110844	normal	0.953448757	0.172732172	normal	0.103525287	0.453348723	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF758)	Tumor necrosis factor alpha-induced protein 8-like protein 2 GN=TNFAIP8L2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor alpha-induced protein 8-like protein 2 [Galeopterus variegatus]
ENSG00000163155(LYSMD1)	--	2.616986907	128	3.037585027	154	4.20290939	186	3.70660111	175	3.077166007	150	3.311111	161	0.844431386	0.416092651	normal	0.96539411	-0.058809224	normal	0.947520492	-0.21465576	normal	0.959389613	0.033425155	normal	--	--	--	--	--	--	--	LysM domain	LysM and putative peptidoglycan-binding domain-containing protein 1 GN=LYSMD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 1 isoform X1 [Vicugna pacos]
ENSG00000163157(TMOD4)	--	0	0	0	0	0.0482702	0	0.0487643	1	0.10849	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: tropomyosin binding (GO:0005523);; Biological Process: pointed-end actin filament capping (GO:0051694);; 	K10370|0|ptr:457286|TMOD4; tropomodulin 4 (muscle); K10370 tropomodulin (A)	--	[Z]	Cytoskeleton	Tropomodulin	Tropomodulin-4 GN=TMOD4 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: tropomodulin-4 [Tupaia chinensis] 
ENSG00000163159(VPS72)	--	24.4023486	688	22.92038369	655	27.634484	733	26.08681347	718	20.866048	588	25.94348	707	0.975047462	0.030675957	normal	0.956493866	-0.176674526	normal	0.974281691	-0.06026781	normal	0.822074488	-0.065617216	normal	--	--	--	"K11664|0|hsa:6944|VPS72, CFL1, Swc2, TCFL1, YL-1, YL1; vacuolar protein sorting 72 homolog (S. cerevisiae); K11664 vacuolar protein sorting-associated protein 72 (A)"	--	[R]	General function prediction only	YL1 nuclear protein;; YL1 nuclear protein C-terminal domain	Vacuolar protein sorting-associated protein 72 homolog GN=VPS72 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: vacuolar protein sorting-associated protein 72 homolog [Camelus ferus] 
ENSG00000163161(ERCC3)	--	22.28828	1246	26.34112	1338	26.24626	1423	15.6637	842	16.68751	866	15.69116	859	0.068568703	-0.595344835	normal	0.025832492	-0.648147504	normal	0.002394348	-0.735480122	normal	5.29E-06	-0.663392989	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K10843|0|hsa:2071|ERCC3, BTF2, GTF2H, RAD25, TFIIH, XPB; excision repair cross-complementation group 3 (EC:3.6.4.12); K10843 DNA excision repair protein ERCC-3 [EC:3.6.4.12] (A)"	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420)	[KL]	"Transcription;; Replication, recombination and repair"	"Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; SNF2 family N-terminal domain"	TFIIH basal transcription factor complex helicase XPB subunit GN=ERCC3 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: TFIIH basal transcription factor complex helicase XPB subunit isoform X1 [Tupaia chinensis] 
ENSG00000163162(RNF149)	--	25.99708466	986	27.03069352	1032	21.35358045	808	22.585901	859	22.53036027	843	22.49525597	844	0.946321522	-0.229378445	normal	0.889198672	-0.312756919	normal	0.976203502	0.054496459	normal	0.412655202	-0.172164663	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K15704|0|hsa:284996|RNF149, DNAPTP2; ring finger protein 149; K15704 E3 ubiquitin-protein ligase RNF149 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; PA domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF149 (Precursor) GN=RNF149 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF149 [Dasypus novemcinctus]
ENSG00000163166(IWS1)	--	18.98563187	1507	17.12510364	1372	19.03297965	1498	12.50610497	980	12.00985732	937	11.54371085	903	0.018942813	-0.650828223	normal	0.123191037	-0.570819776	normal	0.002179574	-0.737561667	normal	5.47E-06	-0.655593308	normal	[S]	Function unknown	Cellular Component: nucleus (GO:0005634);; 	K17498|0|hsa:55677|IWS1; IWS1 homolog (S. cerevisiae); K17498 transcription factor SPN1 (A)	--	[S]	Function unknown	TFIIS helical bundle-like domain	Protein IWS1 homolog GN=IWS1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein IWS1 homolog isoformX1 [Canis lupus familiaris]
ENSG00000163170(BOLA3)	--	74.9465	496	87.9134	552	80.3378	545	70.4431	483	53.8857	354	57.61288	405	0.969363074	-0.068932796	normal	0.045441352	-0.660067632	normal	0.636451133	-0.435219519	normal	0.064426599	-0.380901057	normal	[T]	Signal transduction mechanisms	--	--	--	[T]	Signal transduction mechanisms	BolA-like protein	BolA-like protein 3 GN=BOLA3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bolA-like protein 3 [Orycteropus afer afer]
ENSG00000163171(CDC42EP3)	--	16.4354233	1317	14.256935	1150	20.068133	1464	37.335443	2874	36.474246	2890	27.66667572	2076	6.74E-09	1.094087591	up	1.40E-12	1.30688754	up	0.364372693	0.495167799	normal	3.31E-05	0.974260077	normal	--	--	--	--	--	--	--	Cdc42 effector;; P21-Rho-binding domain	Cdc42 effector protein 3 GN=CDC42EP3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cdc42 effector protein 3 isoform 1 [Dasypus novemcinctus] 
ENSG00000163191(S100A11)	--	530.414	3309	516.597	3295	554.853	3581	838.651	5506	735.518	4584	694.322	4454	0.005128414	0.70352131	normal	0.660232991	0.45472435	normal	0.947898334	0.306331382	normal	0.000917251	0.492237634	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	S-100/ICaBP type calcium binding domain;; EF-hand domain pair;; EF hand;; EF-hand domain	"Protein S100-A11, N-terminally processed GN=S100A11 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	PREDICTED: protein S100-A11 [Tupaia chinensis]
ENSG00000163202(LCE3D)	--	0	0	0	0	0.502361	2	2.20374	13	4.26481	24	1.54393	9	--	--	--	0.000350324	4.066346934	up	--	--	--	--	--	--	--	--	--	--	--	--	--	Late cornified envelope	--	--	--	--
ENSG00000163207(IVL)	--	0	0	0	0	0	0	0.0689199	4	0.118438	6	0.085396	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: keratinization (GO:0031424);; 	--	--	--	--	Involucrin of squamous epithelia N-terminus;; Involucrin repeat	Involucrin GN=IVL OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	involucrin [Tupaia glis]
ENSG00000163214(DHX57)	--	11.462651	1119	11.82865411	1168	12.96778048	1293	10.126633	1007	9.767632876	980	8.368018062	817	0.963957566	-0.182713989	normal	0.926409873	-0.274224983	normal	0.013396715	-0.669611618	normal	0.021758186	-0.374027248	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: metal ion binding (GO:0046872);; 	"K13026|0|hsa:90957|DHX57, DDX57; DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 (EC:3.6.4.13); K13026 ATP-dependent RNA helicase DHX57 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	RWD domain;; Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Putative ATP-dependent RNA helicase DHX57 GN=DHX57 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: putative ATP-dependent RNA helicase DHX57 isoformX1 [Equus caballus] 
ENSG00000163216(SPRR2D)	--	0	0	0.277662	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Small proline-rich 2	--	--	--	--
ENSG00000163219(ARHGAP25)	--	0.296705535	18	0.12724045	7	0.113175397	5	0.184330053	11	0.128453361	7	0.146147344	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; PH domain	Rho GTPase-activating protein 25 GN=ARHGAP25 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 25 isoform X1 [Eptesicus fuscus]
ENSG00000163220(S100A9)	--	0	0	0	0	0.136991	0	0.136007	1	0.700543	4	0.138587	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A9 GN=S100A9 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein S100-A9-like isoform X3 [Equus przewalskii]
ENSG00000163235(TGFA)	--	6.667530969	500	7.60438437	386	9.188383689	615	8.401500146	629	8.507333965	617	8.087651017	514	0.89208949	0.299477727	normal	0.045783168	0.653201641	normal	0.918599853	-0.266391944	normal	0.533368121	0.208569612	normal	--	--	--	"K08774|1.42297e-87|pps:100973153|TGFA; transforming growth factor, alpha; K08774 transforming growth factor, alpha (A)"	ErbB signaling pathway (ko04012);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Glioma (ko05214);; Prostate cancer (ko05215);; Non-small cell lung cancer (ko05223)	--	--	--	Transforming growth factor alpha (Precursor) GN=TGFA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protransforming growth factor alpha isoform X1 [Galeopterus variegatus]
ENSG00000163239(TDRD10)	--	0.033446627	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"Tudor domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Tudor domain-containing protein 10 GN=TDRD10 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: tudor domain-containing protein 10 [Ceratotherium simum simum]
ENSG00000163249(CCNYL1)	--	24.69813697	1538	21.80495577	1372	24.0352588	1396	9.196207216	538	8.959660132	532	6.963336661	437	0	-1.543476619	down	4.02E-13	-1.385660804	down	0	-1.68044445	down	6.50E-28	-1.536473132	down	--	--	Biological Process: regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079);; Molecular Function: protein kinase binding (GO:0019901);; 	--	--	[R]	General function prediction only	"Cyclin, N-terminal domain;; Cyclin"	Cyclin-Y-like protein 1 GN=CCNYL1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cyclin-Y-like protein 1 [Pteropus alecto] 
ENSG00000163251(FZD5)	--	4.53949	507	4.47125	498	3.43916	391	4.09432	456	4.60313	496	4.49059	494	0.952301013	-0.183198414	normal	0.970664004	-0.027149569	normal	0.863700802	0.327920198	normal	0.940283296	0.029421902	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	"K02375|0|hsa:7855|FZD5, C2orf31, HFZ5; frizzled class receptor 5; K02375 frizzled 5/8 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-5 (Precursor) GN=FZD5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: frizzled-5 isoform X1 [Bubalus bubalis] 
ENSG00000163257(DCAF16)	--	5.695519	690	6.0176054	691	5.5035759	637	5.5900319	636	5.542064	645	5.005172	627	0.96375626	-0.148058324	normal	0.967483568	-0.120539983	normal	0.973925423	-0.031045082	normal	0.701627286	-0.102224887	normal	--	--	--	--	--	--	--	DDB1- and CUL4-associated factor 16	DDB1- and CUL4-associated factor 16 GN=DCAF16 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DDB1- and CUL4-associated factor 16 [Galeopterus variegatus] 
ENSG00000163273(NPPC)	--	0.0801246	1	0.385188	4	0.0766054	0	0.712427122	3	0.231067	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	"K12336|3.56153e-34|hsa:4880|NPPC, CNP, CNP2; natriuretic peptide C; K12336 natriuretic peptide C (A)"	--	--	--	Atrial natriuretic peptide	CNP-53 (Precursor) GN=NPPC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: C-type natriuretic peptide [Orcinus orca] 
ENSG00000163281(GNPDA2)	--	9.5416492	372	9.906753486	411	8.977221	350	9.338502115	361	8.937276	332	8.211080509	330	0.966545968	-0.073826494	normal	0.868030488	-0.328035882	normal	0.964661283	-0.092767471	normal	0.565946465	-0.169042104	normal	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; 	K02564|0|ptr:740946|GNPDA2; glucosamine-6-phosphate deaminase 2; K02564 glucosamine-6-phosphate deaminase [EC:3.5.99.6] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	Glucosamine-6-phosphate isomerase 2 GN=GNPDA2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: glucosamine-6-phosphate isomerase 2 isoform X1 [Felis catus] 
ENSG00000163283(ALPP)	--	0.0491204	3	0	0	0.0315166	1	0.0163606	1	0.0317359	1	0.0161225	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: phosphatase activity (GO:0016791);; 	"K01077|0|hsa:250|ALPP, ALP, PALP, PLAP, PLAP-1; alkaline phosphatase, placental (EC:3.1.3.1); K01077 alkaline phosphatase [EC:3.1.3.1] (A)"	Folate biosynthesis (ko00790)	[P]	Inorganic ion transport and metabolism	Alkaline phosphatase	"Alkaline phosphatase, placental type (Precursor) GN=ALPP OS=Homo sapiens (Human) PE=1 SV=2"	P	Inorganic ion transport and metabolism	PREDICTED: intestinal-type alkaline phosphatase [Equus caballus]
ENSG00000163286(ALPPL2)	--	0.0210671	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: phosphatase activity (GO:0016791);; 	"K01077|0|hsa:251|ALPPL2, ALPG, ALPPL, GCAP; alkaline phosphatase, placental-like 2 (EC:3.1.3.1); K01077 alkaline phosphatase [EC:3.1.3.1] (A)"	Folate biosynthesis (ko00790)	[P]	Inorganic ion transport and metabolism	Alkaline phosphatase	"Alkaline phosphatase, placental-like (Precursor) GN=ALPPL2 OS=Homo sapiens (Human) PE=1 SV=4"	P	Inorganic ion transport and metabolism	PREDICTED: intestinal-type alkaline phosphatase-like [Ceratotherium simum simum]
ENSG00000163291(PAQR3)	--	5.97543	645	6.23847	669	6.75918	718	7.22538	809	5.57596	621	6.06669	681	0.898839866	0.295378938	normal	0.965960908	-0.128537826	normal	0.97236446	-0.084437848	normal	0.915487858	0.033351688	normal	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Progestin and adipoQ receptor family member 3 GN=PAQR3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: progestin and adipoQ receptor family member 3 isoform X1 [Tupaia chinensis] 
ENSG00000163293(NIPAL1)	--	0.907596908	75	0.351437753	29	0.950844	68	1.154985734	96	1.208781998	100	0.481671105	40	0.945456899	0.319514414	normal	1.64E-05	1.713456139	up	0.722607033	-0.7517798	normal	0.639651132	0.433887687	normal	--	--	Molecular Function: magnesium ion transmembrane transporter activity (GO:0015095);; Biological Process: magnesium ion transport (GO:0015693);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Magnesium transporter NIPA;; Multidrug resistance efflux transporter;; EamA-like transporter family	Magnesium transporter NIPA3 GN=NIPAL1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: magnesium transporter NIPA3 [Equus caballus]
ENSG00000163297(ANTXR2)	--	2.585597932	183	2.090654433	140	3.013643816	170	2.813596598	202	4.158513617	299	2.205706855	148	0.962358697	0.110793811	normal	8.70E-05	1.065238485	up	0.950763643	-0.206260836	normal	0.522872308	0.375116248	normal	--	--	Molecular Function: receptor activity (GO:0004872);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Anthrax receptor C-terminus region;; Anthrax receptor extracellular domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Anthrax toxin receptor 2 (Precursor) GN=ANTXR2 OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: anthrax toxin receptor 2 isoform X2 [Camelus bactrianus]
ENSG00000163312(HELQ)	--	2.626230964	136	2.9301845	123	3.046959	150	2.532645	122	2.88406033	136	2.629574	124	0.957832338	-0.185345521	normal	0.962906904	0.122093791	normal	0.935980187	-0.2798063	normal	0.821219965	-0.119324832	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[R]	General function prediction only	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Helix-hairpin-helix domain	Helicase POLQ-like GN=HELQ OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: helicase POLQ-like [Odobenus rosmarus divergens]
ENSG00000163319(MRPS18C)	--	21.584583	215	23.402083	228	24.441003	237	23.2961805	250	24.252986	220	18.378838	180	0.950569977	0.185528836	normal	0.963758584	-0.072467493	normal	0.817198476	-0.402226991	normal	0.841951529	-0.087145268	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02963|4.6924e-102|pps:100995168|MRPS18C; mitochondrial ribosomal protein S18C; K02963 small subunit ribosomal protein S18 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S18	"28S ribosomal protein S18c, mitochondrial (Precursor) GN=MRPS18C OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S18c, mitochondrial isoform X1 [Physeter catodon]"
ENSG00000163320(CGGBP1)	--	32.85025701	1914	31.36951639	1768	31.17571211	1835	31.77225231	1950	33.83692221	2030	39.674044	2375	0.986551173	-0.003945831	normal	0.974671371	0.177792883	normal	0.849048311	0.363591922	normal	0.33023268	0.183416181	normal	--	--	--	--	--	--	--	--	CGG triplet repeat-binding protein 1 GN=CGGBP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CGG triplet repeat-binding protein 1 [Orycteropus afer afer]
ENSG00000163322(FAM175A)	--	5.998357	290	4.841243401	224	5.925233	275	7.0325388	331	6.6116048	294	5.519221925	257	0.955220994	0.159156406	normal	0.839117233	0.368712181	normal	0.962519655	-0.105355252	normal	0.684860601	0.138974668	normal	--	--	--	--	--	--	--	--	BRCA1-A complex subunit Abraxas GN=FAM175A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: BRCA1-A complex subunit Abraxas [Galeopterus variegatus]
ENSG00000163328(GPR155)	--	1.415807791	139	1.037068259	89	1.363510649	121	0.814679065	84	0.686184299	70	0.352204559	37	0.250322346	-0.746719762	normal	0.935712428	-0.360943512	normal	2.36E-06	-1.677613186	down	0.033813713	-0.892824098	normal	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: intracellular signal transduction (GO:0035556);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	--	--	"Membrane transport protein;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	Integral membrane protein GPR155 GN=GPR155 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: integral membrane protein GPR155 isoform X1 [Galeopterus variegatus] 
ENSG00000163331(DAPL1)	--	0.819588092	6	0.54178118	4	1.587875474	11	1.185407307	9	1.064086879	7	0.929888534	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	7 transmembrane receptor (rhodopsin family);; Death-associated protein	Olfactory receptor 7E24 GN=OR7E24 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: putative gustatory receptor clone PTE01 [Camelus bactrianus]
ENSG00000163344(PMVK)	--	24.9869	558	26.0477	606	28.4687	659	22.0981	507	21.4832	475	21.7673	489	0.95689993	-0.16862428	normal	0.795094281	-0.371766061	normal	0.611047458	-0.437565291	normal	0.101856811	-0.330627198	normal	--	--	Molecular Function: phosphomevalonate kinase activity (GO:0004631);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: cholesterol biosynthetic process (GO:0006695);; 	"K13273|1.99374e-138|hsa:10654|PMVK, HUMPMKI, PMK, PMKA, PMKASE; phosphomevalonate kinase (EC:2.7.4.2); K13273 phosphomevalonate kinase [EC:2.7.4.2] (A)"	Terpenoid backbone biosynthesis (ko00900);; Peroxisome (ko04146)	--	--	Phosphomevalonate kinase	Phosphomevalonate kinase GN=PMVK OS=Homo sapiens (Human) PE=1 SV=3	H	Coenzyme transport and metabolism	PREDICTED: phosphomevalonate kinase isoform X1 [Equus caballus] 
ENSG00000163346(PBXIP1)	--	18.27925	1310	16.55387	1225	18.26985	1349	16.1659368	1186	17.21931	1236	21.236949	1533	0.968605956	-0.174080363	normal	0.981463454	-0.008519094	normal	0.970723834	0.175990718	normal	0.990102128	0.005833793	normal	--	--	--	--	--	--	--	--	Pre-B-cell leukemia transcription factor-interacting protein 1 GN=PBXIP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: pre-B-cell leukemia transcription factor-interacting protein 1 [Tursiops truncatus]
ENSG00000163347(CLDN1)	--	59.6317	2726	59.9137	2741	64.725	2918	50.9669	2353	43.3556	1977	52.4351	2403	0.964446658	-0.242968937	normal	0.425116072	-0.492494521	normal	0.945066984	-0.288269772	normal	0.03242818	-0.337649729	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|1.79587e-103|ptr:460934|CLDN1; claudin 1; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-1 GN=CLDN1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: claudin-1 [Ailuropoda melanoleuca] 
ENSG00000163348(PYGO2)	--	15.68793	867	13.600773	766	15.779688	887	15.13835826	836	15.04613863	823	14.79545963	823	0.974806785	-0.083211128	normal	0.973513562	0.081965347	normal	0.971914538	-0.116127516	normal	0.88635226	-0.042981664	normal	--	--	--	--	--	--	--	PHD-finger	Pygopus homolog 2 GN=PYGO2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: pygopus homolog 2 [Balaenoptera acutorostrata scammoni]
ENSG00000163349(HIPK1)	--	10.2057659	1226	9.806492047	1229	10.80972537	1306	10.17290078	1216	10.845494	1317	9.8494512	1253	0.981202276	-0.042594415	normal	0.979739041	0.078250848	normal	0.980803033	-0.067979552	normal	0.974200785	-0.011392789	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K08826|0|pps:100973788|HIPK1; homeodomain interacting protein kinase 1; K08826 homeodomain interacting protein kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Homeodomain-interacting protein kinase 1 GN=HIPK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: homeodomain-interacting protein kinase 1 isoform 2 [Trichechus manatus latirostris]
ENSG00000163352(LENEP)	--	1.42319	7	0.195143	1	0.381841	1	0.192539	1	0.197151	0	0.195895	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lens epithelial cell protein LEP503	Lens epithelial cell protein LEP503 GN=LENEP OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: lens epithelial cell protein LEP503 [Bos mutus] 
ENSG00000163354(DCST2)	--	0.311301501	12	0.084060027	3	0.4324541	15	0.056731263	2	0.126110475	4	0.1349695	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	DC-STAMP-like protein	DC-STAMP domain-containing protein 2 GN=DCST2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: DC-STAMP domain-containing protein 2 [Galeopterus variegatus]
ENSG00000163357(DCST1)	--	0.073525457	3	0	0	0.118441916	4	0.048903432	2	0.166622887	6	0.048500785	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	DC-STAMP-like protein	DC-STAMP domain-containing protein 1 GN=DCST1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: DC-STAMP domain-containing protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000163359(COL6A3)	--	0.061189826	5	0.019454548	4	0.029218968	3	0.019797414	4	0.024031549	4	0.00982978	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; 	"K06238|0|hsa:1293|COL6A3; collagen, type VI, alpha 3; K06238 collagen, type VI, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974)	[W]	Extracellular structures	von Willebrand factor type A domain;; von Willebrand factor type A domain;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; Kunitz/Bovine pancreatic trypsin inhibitor domain	Collagen alpha-3(VI) chain (Precursor) GN=COL6A3 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: collagen alpha-3(VI) chain [Panthera tigris altaica]
ENSG00000163362(C1orf106)	--	6.550266499	546	7.585561548	641	6.958505426	590	22.26299953	1837	27.893943	2300	25.96696332	2168	0	1.716754688	up	0	1.819391888	up	0	1.866612759	up	1.44E-26	1.806375458	up	--	--	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF3338)	Uncharacterized protein C1orf106 GN=C1orf106 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C1orf106 homolog isoform X1 [Loxodonta africana]
ENSG00000163374(YY1AP1)	--	17.0962945	1008	17.623649	1015	15.358505	893	15.807677	908	15.35201102	906	16.51588697	976	0.962498933	-0.181272396	normal	0.961421567	-0.185031339	normal	0.972705926	0.119735518	normal	0.733009561	-0.084925705	normal	--	--	--	--	--	--	--	--	YY1-associated protein 1 GN=YY1AP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: GON-4-like protein isoform X4 [Equus przewalskii]
ENSG00000163376(KBTBD8)	--	0.788890904	25	0.246943263	17	0.365115881	24	0.379992932	26	0.50489879	32	0.488716	33	0.986854271	0.024287621	normal	0.917096323	0.836139132	normal	0.974369486	0.428053795	normal	0.575135028	0.443282296	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10475|0|hsa:84541|KBTBD8, TA-KRP; kelch repeat and BTB (POZ) domain containing 8; K10475 kelch repeat and BTB domain-containing protein 8 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"BTB And C-terminal Kelch;; BTB/POZ domain;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain"	Kelch repeat and BTB domain-containing protein 8 GN=KBTBD8 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch repeat and BTB domain-containing protein 8 isoform X2 [Tupaia chinensis]
ENSG00000163378(EOGT)	--	4.456228787	296	5.226400003	301	7.187411154	326	7.001187515	354	4.553041583	310	4.626096676	310	0.937146013	0.226244995	normal	0.966770308	0.020974334	normal	0.965302293	-0.080512136	normal	0.889452211	0.056115222	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K18134|0|hsa:285203|EOGT, AER61, AOS4, C3orf64, EOGT1; EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase (EC:2.4.1.255); K18134 protein O-GlcNAc transferase [EC:2.4.1.255] (A)"	Other types of O-glycan biosynthesis (ko00514)	[S]	Function unknown	Protein of unknown function (DUF563)	EGF domain-specific O-linked N-acetylglucosamine transferase (Precursor) GN=EOGT OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: EGF domain-specific O-linked N-acetylglucosamine transferase [Galeopterus variegatus]
ENSG00000163380(LMOD3)	--	0.011499264	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: tropomyosin binding (GO:0005523);; Biological Process: pointed-end actin filament capping (GO:0051694);; 	--	--	[Z]	Cytoskeleton	Tropomodulin	Leiomodin-3 GN=LMOD3 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: leiomodin-3 [Equus caballus] 
ENSG00000163382(NAXE)	--	95.83876	1688	82.979961	1542	94.96525	1622	87.15343	1523	92.586211	1620	86.435335	1547	0.971891176	-0.179059537	normal	0.983465072	0.049716918	normal	0.982820425	-0.076519004	normal	0.774759408	-0.070075537	normal	[S]	Function unknown	--	"K17759|0|hsa:128240|APOA1BP, AIBP, YJEFN1; apolipoprotein A-I binding protein (EC:5.1.99.6); K17759 NAD(P)H-hydrate epimerase [EC:5.1.99.6] (A)"	--	[S]	Function unknown	YjeF-related protein N-terminus	NAD(P)H-hydrate epimerase {ECO:0000255|HAMAP-Rule:MF_03159} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: NAD(P)H-hydrate epimerase [Galeopterus variegatus]
ENSG00000163389(POGLUT1)	--	5.095870514	273	5.343603888	269	6.73685056	302	6.149011432	301	7.603240947	340	6.04084219	324	0.96218696	0.109443551	normal	0.886325641	0.314924131	normal	0.964230091	0.092705554	normal	0.580311997	0.172562573	normal	--	--	--	"K13667|0|ptr:460605|POGLUT1, KTELC1; protein O-glucosyltransferase 1; K13667 protein glucosyltransferase [EC:2.4.1.-] (A)"	Other types of O-glycan biosynthesis (ko00514)	[R]	General function prediction only	Glycosyl transferase family 90	Protein O-glucosyltransferase 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein O-glucosyltransferase 1 [Condylura cristata]
ENSG00000163393(SLC22A15)	--	1.076257089	56	0.860017805	52	1.372021579	67	1.186456022	57	1.149989921	50	1.421971629	84	0.977636126	-0.005156934	normal	0.976826026	-0.075762881	normal	0.951912334	0.311642366	normal	0.895946735	0.106581525	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08211|0|hsa:55356|SLC22A15, FLIPT1, PRO34686; solute carrier family 22, member 15; K08211 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 15 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 15 GN=SLC22A15 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: solute carrier family 22 member 15 [Orycteropus afer afer]
ENSG00000163395(IGFN1)	--	0.01069051	3	0.010320912	3	0.010316706	2	0.042975	9	0.066415744	18	0.063797333	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Immunoglobulin-like and fibronectin type III domain-containing protein 1 GN=IGFN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: immunoglobulin-like and fibronectin type III domain-containing protein 1 [Ursus maritimus]
ENSG00000163399(ATP1A1)	--	95.24147961	6948	82.5555811	6051	87.10218448	6352	102.8651627	7524	100.7848741	7292	97.44758565	7123	0.994350849	0.084051968	normal	0.981329188	0.247657968	normal	0.991304008	0.156947332	normal	0.447272937	0.159723641	normal	--	--	--	"K01539|0|hsa:476|ATP1A1; ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9); K01539 sodium/potassium-transporting ATPase subunit alpha [EC:3.6.3.9] (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Insulin secretion (ko04911);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Proximal tubule bicarbonate reclamation (ko04964);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Carbohydrate digestion and absorption (ko04973);; Protein digestion and absorption (ko04974);; Bile secretion (ko04976);; Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Sodium/potassium-transporting ATPase subunit alpha-1 (Precursor) GN=ATP1A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium-transporting ATPase subunit alpha-1 isoform X2 [Tupaia chinensis]
ENSG00000163406(SLC15A2)	--	0.212641403	16	0.179436603	15	0.242349616	15	0.279277513	15	0.259470863	14	0.112343135	9	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K14637|0|ptr:460627|SLC15A2; solute carrier family 15 (oligopeptide transporter), member 2; K14637 solute carrier family 15 (oligopeptide transporter), member 2 (A)"	--	[E]	Amino acid transport and metabolism	POT family	Solute carrier family 15 member 2 GN=SLC15A2 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 15 member 2 isoform 1 [Ceratotherium simum simum]
ENSG00000163412(EIF4E3)	--	4.691182792	299	4.501621	302	4.100781505	257	6.496325227	415	6.974281486	430	6.165953633	360	0.659050426	0.440206144	normal	0.519338207	0.486311081	normal	0.582608556	0.475561979	normal	0.035300492	0.468158876	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation initiation factor activity (GO:0003743);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: translational initiation (GO:0006413);; 	--	--	--	--	Eukaryotic initiation factor 4E	Eukaryotic translation initiation factor 4E type 3 GN=EIF4E3 OS=Homo sapiens (Human) PE=2 SV=4	J	"Translation, ribosomal structure and biogenesis"	eukaryotic translation initiation factor 4E type 3 [Bos taurus] 
ENSG00000163428(LRRC58)	--	19.54474	2276	23.54198	2727	21.28948	2429	17.14162	2018	15.90496	1859	18.40885	2156	0.971735089	-0.204260091	normal	0.120989303	-0.573826534	normal	0.977408188	-0.180177608	normal	0.04344204	-0.321996826	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 58 GN=LRRC58 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 58 [Bubalus bubalis]
ENSG00000163430(FSTL1)	--	39.70348788	3119	40.9263448	2911	36.27722273	2866	79.45239314	6107	73.02192688	5706	63.0832507	4738	2.19E-06	0.938211899	normal	2.46E-06	0.949179767	normal	0.00334048	0.716651007	normal	4.09E-09	0.873697109	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Follistatin/Osteonectin-like EGF domain	Follistatin-related protein 1 (Precursor) GN=FSTL1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	Fstl1 [Sus scrofa]
ENSG00000163431(LMOD1)	--	0.207971	22	0.1696269	15	0.110264	11	0.0569043	6	0.06681659	6	0.06741116	7	0.621418684	-1.66962202	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: protein binding (GO:0005515);; Molecular Function: tropomyosin binding (GO:0005523);; Biological Process: pointed-end actin filament capping (GO:0051694);; 	--	--	[Z]	Cytoskeleton	Tropomodulin;; WH2 motif	Leiomodin-1 GN=LMOD1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: leiomodin-1 isoform X1 [Galeopterus variegatus] 
ENSG00000163435(ELF3)	--	80.03108264	4194	115.0698006	5596	77.49322335	4015	63.43490055	3334	61.22717992	3240	111.9791121	6024	0.890253822	-0.361755996	normal	0.000284353	-0.809537413	normal	0.131430207	0.576851773	normal	0.830751125	-0.151801217	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09429|0|ptr:739176|ELF3; E74-like factor 3 (ets domain transcription factor, epithelial-specific ); K09429 E74-like factor 3 (A)"	--	[K]	Transcription	Ets-domain;; Sterile alpha motif (SAM)/Pointed domain	ETS-related transcription factor Elf-3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ETS-related transcription factor Elf-3 [Galeopterus variegatus] 
ENSG00000163444(TMEM183A)	--	22.49812	1094	21.946668	1071	20.078506	968	25.489959	1248	27.26082	1318	27.590923	1340	0.970339473	0.158963808	normal	0.927133696	0.277611435	normal	0.502270292	0.460248878	normal	0.080091779	0.296996096	normal	--	--	--	--	--	--	--	--	Transmembrane protein 183A GN=TMEM183A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 183A [Oryctolagus cuniculus]
ENSG00000163449(TMEM169)	--	0.665716808	32	0.824675035	22	0.39223931	23	0.213648156	13	0.413228548	25	0.13006266	7	0.675622781	-1.234550663	normal	0.985707881	0.153119849	normal	0.693190767	-1.533185532	normal	0.266006162	-0.79703982	normal	--	--	--	--	--	--	--	TMEM169 protein family	Transmembrane protein 169 GN=TMEM169 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 169 isoform X1 [Equus caballus] 
ENSG00000163453(IGFBP7)	--	54.68215	1228	54.84965	1270	57.87477	1333	106.74499	2436	146.46253	3298	100.36682	2275	1.57E-06	0.956505988	normal	1.17E-13	1.354298479	up	0.000885252	0.762228667	normal	0.000130107	1.042818783	up	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Immunoglobulin I-set domain;; Kazal-type serine protease inhibitor domain;; Immunoglobulin domain;; Kazal-type serine protease inhibitor domain;; Insulin-like growth factor binding protein	Insulin-like growth factor-binding protein 7 (Precursor) GN=IGFBP7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: insulin-like growth factor-binding protein 7 [Trichechus manatus latirostris]
ENSG00000163462(TRIM46)	--	1.597867627	96	1.048158447	64	1.51439657	96	1.726362759	99	1.985858647	117	1.760386349	105	0.971253656	0.01335144	normal	0.19916799	0.834156656	normal	0.967452801	0.119195657	normal	0.527901597	0.305900326	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K12022|0|pps:100987001|TRIM46; tripartite motif containing 46; K12022 tripartite motif-containing protein 46 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"B-box zinc finger;; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 46 GN=TRIM46 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 46 isoform 1 [Dasypus novemcinctus]
ENSG00000163463(KRTCAP2)	--	117.694	538	120.95	567	109.196	517	130.991	626	142.035	651	143.062	668	0.953286629	0.1872282	normal	0.956010898	0.177440307	normal	0.810884695	0.360462368	normal	0.261049634	0.240884008	normal	--	--	--	--	--	[S]	Function unknown	Keratinocyte-associated protein 2	Keratinocyte-associated protein 2 GN=KRTCAP2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: keratinocyte-associated protein 2 [Tupaia chinensis]
ENSG00000163466(ARPC2)	--	145.421367	4004	147.2543786	4113	140.2106367	3909	131.396478	3658	114.4106113	3147	101.8438163	2827	0.986229991	-0.161154433	normal	0.805742611	-0.407468608	normal	0.519335092	-0.475601801	normal	0.032443735	-0.342312457	normal	--	--	Cellular Component: Arp2/3 protein complex (GO:0005885);; Cellular Component: actin cytoskeleton (GO:0015629);; Biological Process: regulation of actin filament polymerization (GO:0030833);; Biological Process: Arp2/3 complex-mediated actin nucleation (GO:0034314);; 	"K05758|0|umr:103662770|ARPC2; actin related protein 2/3 complex, subunit 2, 34kDa; K05758 actin related protein 2/3 complex, subunit 2 (A)"	Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Arp2/3 complex, 34 kD subunit p34-Arc"	Actin-related protein 2/3 complex subunit 2 GN=ARPC2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: actin-related protein 2/3 complex subunit 2 [Equus przewalskii]
ENSG00000163467(TSACC)	--	2.59972	13	1.25139	7	0.490527	3	1.971948	15	0.839788	4	1.622328	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: chaperone binding (GO:0051087);; 	--	--	--	--	--	TSSK6-activating co-chaperone protein GN=TSACC OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: TSSK6-activating co-chaperone protein [Ursus maritimus]
ENSG00000163468(CCT3)	--	195.7474947	8388	185.1163234	8017	212.7425078	9025	210.9769868	9106	212.2244741	8973	162.3601407	7012	0.995100485	0.087642925	normal	0.993315623	0.141076215	normal	0.921973894	-0.372321402	normal	0.891022858	-0.041074008	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09495|0|pps:100975912|CCT3; chaperonin containing TCP1, subunit 3 (gamma); K09495 T-complex protein 1 subunit gamma (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit gamma GN=CCT3 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: T-complex protein 1 subunit gamma [Loxodonta africana]
ENSG00000163472(TMEM79)	--	5.140031789	173	4.987084277	156	4.795008756	146	4.883463018	176	5.573627381	182	5.60819	204	0.967275648	-0.005976252	normal	0.94971835	0.19917687	normal	0.737216039	0.470171085	normal	0.570729717	0.221706872	normal	--	--	--	--	--	--	--	--	Transmembrane protein 79 GN=TMEM79 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 79 [Leptonychotes weddellii]
ENSG00000163479(SSR2)	--	142.072124	2291	123.5546328	1982	120.1336527	1917	172.5358694	2778	179.64525	2868	183.888942	2985	0.962935799	0.247086216	normal	0.342713416	0.511335473	normal	0.030159984	0.630187577	normal	0.001884644	0.458462296	normal	--	--	--	"K13250|9.39668e-122|tup:102490215|SSR2; signal sequence receptor, beta (translocon-associated protein beta); K13250 translocon-associated protein subunit beta (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Translocon-associated protein beta (TRAPB)	Translocon-associated protein subunit beta (Precursor) GN=SSR2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: translocon-associated protein subunit beta [Tupaia chinensis]
ENSG00000163481(RNF25)	--	11.74406	395	9.54598	331	10.5866	366	7.51112	269	8.78531	295	8.00165	273	0.212836027	-0.582315433	normal	0.948360128	-0.186638956	normal	0.705336181	-0.429173301	normal	0.08876281	-0.404719627	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10640|0|hsa:64320|RNF25, AO7; ring finger protein 25; K10640 E3 ubiquitin-protein ligase RNF25 [EC:6.3.2.19] (A)"	--	[S]	Function unknown	RWD domain;; Ring finger domain	E3 ubiquitin-protein ligase RNF25 GN=RNF25 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF25 [Galeopterus variegatus]
ENSG00000163482(STK36)	--	4.505624202	431	5.118670201	488	4.432756168	425	3.979729372	366	4.172116986	375	5.014756024	476	0.917608815	-0.265647422	normal	0.746121369	-0.399998555	normal	0.958286307	0.154686939	normal	0.548558093	-0.16378116	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06228|0|ptr:459948|STK36; serine/threonine kinase 36; K06228 fused [EC:2.7.11.1] (A)	Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; HEAT repeats;; HEAT repeat	Serine/threonine-protein kinase 36 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 36 [Ursus maritimus]
ENSG00000163485(ADORA1)	--	1.1160399	42	0.693668253	18	0.852582	37	2.475373269	78	3.6972189	114	0.757694587	38	0.495027554	0.839401596	normal	2.47E-11	2.545135579	up	0.982223	0.029012576	normal	0.168492753	1.223704799	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04265|0|hsa:134|ADORA1, RDC7; adenosine A1 receptor; K04265 adenosine A1 receptor (A)"	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Sphingolipid signaling pathway (ko04071);; Neuroactive ligand-receptor interaction (ko04080);; Morphine addiction (ko05032)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Adenosine receptor A1 GN=ADORA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: adenosine receptor A1 [Camelus ferus] 
ENSG00000163491(NEK10)	--	0.099708194	12	0.227805356	9	0.170946174	17	1.248843596	105	1.4361421	85	1.229277899	78	8.18E-13	2.947563866	up	5.24E-11	3.0211308	up	3.32E-06	2.094820698	up	1.76E-10	2.796985465	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08857|0|pps:100989416|NEK10; NIMA-related kinase 10; K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Phosphotransferase enzyme family;; RIO1 family	Serine/threonine-protein kinase Nek10 GN=NEK10 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Nek10 isoform X6 [Canis lupus familiaris] 
ENSG00000163501(IHH)	--	0.029259	1	0.11358	4	0.0277691	0	0	0	0.0568296	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: proteolysis (GO:0006508);; Biological Process: cell-cell signaling (GO:0007267);; Molecular Function: peptidase activity (GO:0008233);; 	"K11989|0|hsa:3549|IHH, BDA1, HHG2; indian hedgehog; K11989 indian hedgehog (A)"	Hedgehog signaling pathway (ko04340)	[T]	Signal transduction mechanisms	Hedgehog amino-terminal signalling domain;; Hint module	Indian hedgehog protein C-product (Precursor) GN=IHH OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: indian hedgehog protein [Tursiops truncatus]
ENSG00000163507(KIAA1524)	--	16.98695495	1279	18.783473	1368	21.13075029	1464	16.439164	1306	13.994553	1059	13.36234035	1011	0.982450155	-0.000692807	normal	0.764396322	-0.390300324	normal	0.1808127	-0.54174662	normal	0.06771212	-0.306034413	normal	--	--	--	--	--	--	--	--	Protein CIP2A GN=KIAA1524 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein CIP2A isoform X1 [Leptonychotes weddellii] 
ENSG00000163508(EOMES)	--	0.815553134	40	0.5597956	30	0.597969945	31	0.344575543	16	0.349585843	17	0.4709333	24	0.401910628	-1.272931667	normal	0.935745952	-0.787468666	normal	0.979064663	-0.357645661	normal	0.18398382	-0.845448866	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10173|0|hsa:8320|EOMES, TBR2; eomesodermin; K10173 eomesodermin protein (A)"	--	[K]	Transcription	T-box	Eomesodermin homolog GN=EOMES OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: eomesodermin homolog isoform 1 [Ceratotherium simum simum]
ENSG00000163510(CWC22)	--	7.657004451	537	8.79322893	583	7.084651314	479	4.802861318	348	5.846111527	421	4.973839995	337	0.046093759	-0.654321562	normal	0.450709211	-0.489600547	normal	0.385954265	-0.513624994	normal	0.003925005	-0.553278368	normal	--	--	--	"K13100|0|hsa:57703|CWC22, EIF4GL, NCM, fSAPb; CWC22 spliceosome-associated protein; K13100 pre-mRNA-splicing factor CWC22 (A)"	--	[R]	General function prediction only	MIF4G domain;; MA3 domain	Pre-mRNA-splicing factor CWC22 homolog GN=CWC22 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: pre-mRNA-splicing factor CWC22 homolog isoformX2 [Equus caballus] 
ENSG00000163512(AZI2)	--	15.83841163	796	14.23686545	755	13.22557173	719	13.29646364	669	15.37466587	637	15.47514835	782	0.911262698	-0.281001929	normal	0.921869985	-0.2660289	normal	0.970570625	0.112658127	normal	0.547546917	-0.141444672	normal	--	--	--	K12651|0|pps:100987620|AZI2; 5-azacytidine induced 2; K12651 5-azacytidine-induced protein 2 (A)	RIG-I-like receptor signaling pathway (ko04622)	--	--	TBD domain	5-azacytidine-induced protein 2 GN=AZI2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 5-azacytidine-induced protein 2 [Leptonychotes weddellii]
ENSG00000163513(TGFBR2)	--	67.9748	5847	66.112	5684	62.7411	5357	66.6536	5707	83.5715	7142	65.20237	5599	0.993604846	-0.065778795	normal	0.962680912	0.307921798	normal	0.993465276	0.055437133	normal	0.643850771	0.10622443	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transforming growth factor beta receptor activity, type II (GO:0005026);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: metal ion binding (GO:0046872);; "	"K04388|0|hsa:7048|TGFBR2, AAT3, FAA3, LDS1B, LDS2, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII; transforming growth factor, beta receptor II (70/80kDa) (EC:2.7.11.30); K04388 TGF-beta receptor type-2 [EC:2.7.11.30] (A)"	MAPK signaling pathway (ko04010);; Cytokine-cytokine receptor interaction (ko04060);; FoxO signaling pathway (ko04068);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350);; Osteoclast differentiation (ko04380);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Chagas disease (American trypanosomiasis) (ko05142);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Transforming growth factor beta receptor 2 ectodomain;; Protein kinase domain;; Protein tyrosine kinase	TGF-beta receptor type-2 (Precursor) GN=TGFBR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: TGF-beta receptor type-2 isoform X1 [Galeopterus variegatus]
ENSG00000163516(ANKZF1)	--	6.774484027	334	8.648836	444	8.647475	447	6.602180116	360	5.140277015	268	6.620507	341	0.965954047	0.076975441	normal	0.013230017	-0.746444248	normal	0.754940462	-0.397250923	normal	0.161964824	-0.359506968	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat and zinc finger domain-containing protein 1 GN=ANKZF1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and zinc finger domain-containing protein 1 isoform 2 [Ceratotherium simum simum]
ENSG00000163517(HDAC11)	--	7.537907	365	7.15932947	288	7.2468446	385	6.035537189	310	7.875136035	355	6.0711521	254	0.918989512	-0.265247298	normal	0.911097879	0.279002065	normal	0.166594558	-0.60537229	normal	0.520310849	-0.196944953	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	K11418|0|pon:100438699|HDAC11; histone deacetylase 11; K11418 histone deacetylase 11 [EC:3.5.1.98] (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain	Histone deacetylase 11 GN=HDAC11 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 11 isoform 1 [Ceratotherium simum simum]
ENSG00000163520(FBLN2)	--	0.200117719	18	0.142488386	12	0.153710895	13	0.419793191	15	0.698375713	61	0.109131759	9	--	--	--	3.43E-05	2.189899735	up	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; 	K17307|0|hsa:2199|FBLN2; fibulin 2; K17307 fibulin 1/2 (A)	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Coagulation Factor Xa inhibitory site;; Anaphylotoxin-like domain;; EGF-like domain	Fibulin-2 (Precursor) GN=FBLN2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: fibulin-2 isoform X1 [Galeopterus variegatus]
ENSG00000163521(GLB1L)	--	9.615512527	226	6.633517025	177	4.678919	160	3.9531094	146	3.82400664	121	3.8919438	120	0.212822451	-0.655593776	normal	0.574196119	-0.564300481	normal	0.852042569	-0.418742744	normal	0.069889357	-0.562989124	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: beta-galactosidase activity (GO:0004565);; Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: beta-galactosidase complex (GO:0009341);; 	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 35;; Beta-galactosidase	Beta-galactosidase-1-like protein (Precursor) GN=GLB1L OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: beta-galactosidase-1-like protein isoform X2 [Felis catus]
ENSG00000163527(STT3B)	--	102.91921	6716	101.92517	6688	98.5313	6335	89.25987	5872	90.04982	5862	105.07938	6890	0.98440647	-0.224527538	normal	0.98598118	-0.211557296	normal	0.993118241	0.112842085	normal	0.652249146	-0.104710063	normal	[R]	General function prediction only	Molecular Function: oligosaccharyl transferase activity (GO:0004576);; Biological Process: protein glycosylation (GO:0006486);; Cellular Component: membrane (GO:0016020);; 	"K07151|0|ptr:746396|STT3B; STT3B, subunit of the oligosaccharyltransferase complex (catalytic); K07151 dolichyl-diphosphooligosaccharide--protein glycosyltransferase [EC:2.4.99.18] (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Oligosaccharyl transferase STT3 subunit	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B GN=STT3B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B isoform 1 [Canis lupus familiaris] 
ENSG00000163528(CHCHD4)	--	17.34157	453	15.73863	419	18.45639	490	16.53176	440	17.53105	457	13.716048	358	0.968235419	-0.072589958	normal	0.964627018	0.103459743	normal	0.572388382	-0.45944765	normal	0.624077398	-0.139525336	normal	--	--	--	K17782|9.47619e-85|nle:100588720|CHCHD4; coiled-coil-helix-coiled-coil-helix domain containing 4; K17782 mitochondrial intermembrane space import and assembly protein 40 (A)	--	[S]	Function unknown	CHCH domain	Mitochondrial intermembrane space import and assembly protein 40 GN=CHCHD4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitochondrial intermembrane space import and assembly protein 40 [Dasypus novemcinctus]
ENSG00000163530(DPPA2)	--	0.0418374	1	0	0	0	0	0	0	0	0	0.0414048	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Dppa2/4 conserved region in higher vertebrates;; Dppa2/4 conserved region	Developmental pluripotency-associated protein 2 GN=DPPA2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: developmental pluripotency associated 2 [Trichechus manatus latirostris]
ENSG00000163531(NFASC)	--	0.559157268	64	0.679552045	58	0.499039622	60	0.878925741	73	0.833723002	47	0.663281491	40	0.971459726	0.155495434	normal	0.962849759	-0.315657723	normal	0.904415438	-0.575374678	normal	0.765989308	-0.209040474	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06757|0|hsa:23114|NFASC, NF, NRCAML; neurofascin; K06757 neurofascin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Bravo-like intracellular region;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein E;; Penicillin-Binding Protein C-terminus Family;; CD47 immunoglobulin-like domain	Neurofascin (Precursor) GN=NFASC OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: neurofascin isoform X2 [Vicugna pacos]
ENSG00000163535(SGO2)	--	12.08641909	1007	10.455413	862	13.08589931	1061	6.959749	574	6.621981	533	4.76861	421	0.000203432	-0.840051613	normal	0.008385455	-0.713371076	normal	5.45E-12	-1.338685023	down	8.50E-10	-0.96106115	normal	--	--	--	K11581|0|ptr:459862|SGOL2; shugoshin-like 2 (S. pombe); K11581 shugoshin-like 2 (A)	--	--	--	--	Shugoshin-like 2 GN=SGOL2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: shugoshin-like 2 [Galeopterus variegatus]
ENSG00000163536(SERPINI1)	--	6.750908887	184	7.458824833	190	7.170607	164	0.666556602	13	0.7467826	24	2.142527444	49	0	-3.70302914	down	0	-2.928879723	down	2.32E-08	-1.720361471	down	1.23E-16	-2.662907837	down	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Neuroserpin (Precursor) GN=SERPINI1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: neuroserpin isoform X3 [Canis lupus familiaris] 
ENSG00000163539(CLASP2)	--	11.6662982	1246	11.78437811	1370	15.31278782	1391	11.79234247	1328	12.43876657	1338	12.8098315	1454	0.981129394	0.061045897	normal	0.981548583	-0.055462382	normal	0.982532803	0.055554328	normal	0.954960941	0.019290091	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K16578|0|ptr:460258|CLASP2; cytoplasmic linker associated protein 2; K16578 CLIP-associating protein 1/2 (A)	--	[R]	General function prediction only	CLASP N terminal;; HEAT repeat;; HEAT repeats;; HEAT-like repeat;; Rix1 complex component involved in 60S ribosome maturation;; non-SMC mitotic condensation complex subunit 1	CLIP-associating protein 2 GN=CLASP2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: CLIP-associating protein 2 [Ceratotherium simum simum]
ENSG00000163541(SUCLG1)	--	50.1899	1190	47.5302	1143	44.8314	1071	50.8935	1221	48.4057	1137	39.6235	942	0.981664873	0.006261383	normal	0.980324193	-0.028981262	normal	0.96049015	-0.193159916	normal	0.797742141	-0.066841581	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; Molecular Function: cofactor binding (GO:0048037);; 	"K01899|0|hsa:8802|SUCLG1, GALPHA, MTDPS9, SUCLA1; succinate-CoA ligase, alpha subunit (EC:6.2.1.4 6.2.1.5); K01899 succinyl-CoA synthetase alpha subunit [EC:6.2.1.4 6.2.1.5] (A)"	Citrate cycle (TCA cycle) (ko00020);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	CoA binding domain;; CoA-ligase;; Succinyl-CoA ligase like flavodoxin domain;; CoA binding domain	"Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial (Precursor) GN=SUCLG1 OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"PREDICTED: succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000163545(NUAK2)	--	16.1183	1050	22.6719	1477	29.0368	1906	21.4861	1390	23.4353	1516	26.1138	1707	0.796346908	0.373387112	normal	0.983553788	0.016157041	normal	0.975855919	-0.167236213	normal	0.956592571	0.037574289	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08800|0|nle:100599279|NUAK2; NUAK family, SNF1-like kinase, 2; K08800 NUAK family, SNF1-like kinase [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family	NUAK family SNF1-like kinase 2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: NUAK family SNF1-like kinase 2 [Ceratotherium simum simum]
ENSG00000163554(SPTA1)	--	0.010281381	2	0.01099623	2	0.010942666	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06114|0|hsa:6708|SPTA1, EL2, HPP, HS3, SPH3, SPTA; spectrin, alpha, erythrocytic 1; K06114 spectrin alpha (A)"	--	[Z]	Cytoskeleton	Spectrin repeat;; Ca2+ insensitive EF hand;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	"Spectrin alpha chain, erythrocytic 1 GN=SPTA1 OS=Homo sapiens (Human) PE=1 SV=5"	Z	Cytoskeleton	"PREDICTED: spectrin alpha chain, erythrocytic 1 [Orycteropus afer afer]"
ENSG00000163558(PRKCI)	--	16.9503	1309	17.1746	1330	16.5837	1262	18.4813	1440	16.8586	1297	14.3947	1111	0.97908034	0.106652074	normal	0.981115156	-0.05760799	normal	0.96380899	-0.191899268	normal	0.883948186	-0.04177789	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K06069|0|pps:100979245|PRKCI; protein kinase C, iota; K06069 atypical protein kinase C iota type [EC:2.7.11.13] (A)"	Rap1 signaling pathway (ko04015);; Endocytosis (ko04144);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Platelet activation (ko04611);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PB1 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Protein kinase C terminal domain;; Kinase-like	Protein kinase C iota type GN=PRKCI OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein kinase C iota type [Camelus bactrianus] 
ENSG00000163564(PYHIN1)	--	0	0	0	0	0	0	0.036565019	1	0	0	0.072944164	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	HIN-200/IF120x domain;; PAAD/DAPIN/Pyrin domain	Pyrin and HIN domain-containing protein 1 GN=PYHIN1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myeloid cell nuclear differentiation antigen-like isoform X1 [Galeopterus variegatus] 
ENSG00000163565(IFI16)	--	5.78003179	289	6.927751	329	4.7796485	259	11.11874813	494	10.81399767	426	14.55296442	591	0.010918862	0.739569008	normal	0.841570742	0.349922334	normal	6.04E-08	1.177236854	up	0.000871215	0.763808833	normal	--	--	--	--	--	--	--	HIN-200/IF120x domain;; PAAD/DAPIN/Pyrin domain	Gamma-interferon-inducible protein 16 GN=IFI16 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	hypothetical protein PANDA_017077 [Ailuropoda melanoleuca]
ENSG00000163576(EFHB)	--	0.106637806	5	0.097207475	1	0.069241639	2	0.563319859	27	0.70740068	38	0.570140243	24	0.101683993	2.099847257	normal	8.75E-07	3.96067315	up	0.012860886	2.854449432	normal	6.05E-07	3.454093347	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand;; Secreted protein acidic and rich in cysteine Ca binding region	EF-hand domain-containing family member B GN=EFHB OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: EF-hand domain-containing family member B [Ceratotherium simum simum]
ENSG00000163577(EIF5A2)	--	6.430007646	431	5.691415246	407	8.123437693	426	5.217386306	350	4.434045088	317	5.05531577	367	0.863596779	-0.329857531	normal	0.797003364	-0.380366475	normal	0.938681438	-0.222512925	normal	0.188926597	-0.310812379	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation elongation factor activity (GO:0003746);; Biological Process: translational frameshifting (GO:0006452);; Molecular Function: ribosome binding (GO:0043022);; Biological Process: positive regulation of translational elongation (GO:0045901);; Biological Process: positive regulation of translational termination (GO:0045905);; 	"K03263|7.0502e-110|rno:310261|Eif5a2, eIF5AII; eukaryotic translation initiation factor 5A2; K03263 translation initiation factor 5A (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	"Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold"	Eukaryotic translation initiation factor 5A-2 GN=EIF5A2 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	"Eukaryotic translation initiation factor 5A-2, partial [Bos mutus]"
ENSG00000163584(RPL22L1)	--	105.66189	985	92.56587	799	131.8823	1150	108.69195	981	77.8721	745	50.78504	433	0.978848624	-0.036645574	normal	0.96923661	-0.122142157	normal	1.41E-13	-1.414332492	down	0.336318432	-0.465480311	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02891|8.49328e-57|ggo:101154166|RPL22L1; 60S ribosomal protein L22-like 1; K02891 large subunit ribosomal protein L22e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L22e protein family	60S ribosomal protein L22-like 1 GN=RPL22L1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L22-like 1-like isoform 2 [Dasypus novemcinctus]
ENSG00000163586(FABP1)	--	0	0	0.140265093	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08750|8.68623e-85|ptr:736471|FABP1; fatty acid binding protein 1, liver; K08750 fatty acid-binding protein 1, liver (A)"	PPAR signaling pathway (ko03320);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin / cytosolic fatty-acid binding protein family	"Fatty acid-binding protein, liver GN=FABP1 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: fatty acid-binding protein, liver [Ailuropoda melanoleuca]"
ENSG00000163590(PPM1L)	--	0.46478736	68	0.830270337	57	0.863739077	61	1.041640748	104	1.97319736	158	0.810506321	99	0.783188217	0.571632641	normal	1.04E-05	1.425807914	up	0.634246581	0.677031397	normal	0.015588288	0.935612307	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K17506|0|ptr:742596|PPM1L; protein phosphatase, Mg2+/Mn2+ dependent, 1L; K17506 protein phosphatase 1L [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C;; Protein phosphatase 2C;; Stage II sporulation protein E (SpoIIE)	Protein phosphatase 1L GN=PPM1L OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1L [Canis lupus familiaris] 
ENSG00000163596(ICA1L)	--	1.617652956	125	2.046277071	137	0.978904249	89	0.993505168	60	1.573057153	92	1.613543342	84	0.010031712	-1.070299757	normal	0.634637572	-0.587922442	normal	0.970705738	-0.090130776	normal	0.129255448	-0.593474198	normal	--	--	Molecular Function: protein domain specific binding (GO:0019904);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Islet cell autoantigen ICA69, C-terminal domain;; Arfaptin-like domain"	Islet cell autoantigen 1-like protein GN=ICA1L OS=Homo sapiens (Human) PE=2 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: islet cell autoantigen 1-like protein [Tupaia chinensis]
ENSG00000163602(RYBP)	--	6.475040202	795	5.931790067	724	5.441669267	655	6.385682228	786	6.658892	814	5.870420054	722	0.975900037	-0.047166135	normal	0.965504604	0.147322205	normal	0.966971498	0.131922278	normal	0.788761777	0.073379889	normal	--	--	--	K11469|1.36623e-75|ptr:460506|RYBP; RING1 and YY1 binding protein; K11469 RING1 and YY1-binding protein (A)	--	[K]	Transcription	Zn-finger in Ran binding protein and others	RING1 and YY1-binding protein GN=RYBP OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: RING1 and YY1-binding protein [Condylura cristata]
ENSG00000163605(PPP4R2)	--	30.47300187	1582	46.04964557	1645	37.11392102	1540	33.67049783	1708	32.76502736	1797	27.89659679	1633	0.983036348	0.079651655	normal	0.981575683	0.105983028	normal	0.9828457	0.076230294	normal	0.708707501	0.08675255	normal	--	--	Molecular Function: protein phosphatase regulator activity (GO:0019888);; Cellular Component: protein phosphatase 4 complex (GO:0030289);; 	"K15425|0|hsa:151987|PPP4R2, PP4R2; protein phosphatase 4, regulatory subunit 2; K15425 serine/threonine-protein phosphatase 4 regulatory subunit 2 (A)"	--	[R]	General function prediction only	PPP4R2	Serine/threonine-protein phosphatase 4 regulatory subunit 2 GN=PPP4R2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 2 isoform X2 [Leptonychotes weddellii]
ENSG00000163606(CD200R1)	--	0	0	0	0	0	0	0	0	0.03270257	0	0.06693486	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CD80-like C2-set immunoglobulin domain	Cell surface glycoprotein CD200 receptor 1 (Precursor) GN=UNQ2522/PRO6015 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cell surface glycoprotein CD200 receptor 1-like [Galeopterus variegatus]
ENSG00000163607(GTPBP8)	--	9.571665239	223	11.34784004	264	11.92808708	269	13.55927668	328	12.87124082	292	11.509313	271	0.459526087	0.522833427	normal	0.95949162	0.123331931	normal	0.967430519	0.002381896	normal	0.483683539	0.215402473	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	GTP-binding protein 8 GN=GTPBP8 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: GTP-binding protein 8 [Galeopterus variegatus]
ENSG00000163608(NEPRO)	--	13.86593401	1014	13.0851759	952	13.143696	937	14.04997809	1001	15.30168156	1120	12.34532856	911	0.978724244	-0.049372645	normal	0.954969357	0.212726871	normal	0.977786158	-0.048809539	normal	0.886955568	0.041277643	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4477)	Uncharacterized protein C3orf17 GN=C3orf17 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C3orf17 homolog isoform X1 [Galeopterus variegatus]
ENSG00000163611(SPICE1)	--	5.084246251	499	5.130789539	538	6.180921464	567	5.552589274	714	7.781031669	789	6.625799837	771	0.428758289	0.484798262	normal	0.270526231	0.529756034	normal	0.613361184	0.43409405	normal	0.005631538	0.482780856	normal	--	--	Biological Process: spindle assembly involved in mitosis (GO:0090307);; 	"K16490|0|hsa:152185|SPICE1, CCDC52, SPICE; spindle and centriole associated protein 1; K16490 spindle and centriole-associated protein 1 (A)"	--	--	--	--	Spindle and centriole-associated protein 1 GN=SPICE1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: spindle and centriole-associated protein 1 [Ceratotherium simum simum]
ENSG00000163617(CCDC191)	--	1.961156005	163	1.793915179	148	2.203197339	171	1.720219	164	1.846754	164	1.531903	151	0.967361486	-0.021803525	normal	0.960914351	0.125453957	normal	0.954259754	-0.185987633	normal	0.964739885	-0.030228339	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein KIAA1407 GN=KIAA1407 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein KIAA1407 homolog [Galeopterus variegatus]
ENSG00000163623(NKX6-1)	--	0.951890707	40	0.550145134	21	0.479028324	18	0.833989329	35	1.250847494	51	0.489499875	21	0.97928492	-0.214655096	normal	0.264421728	1.201544064	normal	0.987968866	0.198638097	normal	0.673078859	0.414925089	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K08030|2.29426e-132|ocu:100352599|NKX6-1; NK6 homeobox 1; K08030 homeobox protein Nkx-6.1 (A)	Maturity onset diabetes of the young (ko04950)	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-6.1 GN=NKX6-1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein Nkx-6.1 [Oryctolagus cuniculus]
ENSG00000163624(CDS1)	--	1.008647802	67	1.136656	75	1.0713058	70	2.202023863	150	1.889398503	124	1.442775998	98	0.00216208	1.114390805	up	0.460487502	0.692979509	normal	0.885705791	0.46854275	normal	0.030641247	0.788722784	normal	[I]	Lipid transport and metabolism	--	"K00981|0|hsa:1040|CDS1, CDS; CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (EC:2.7.7.41); K00981 phosphatidate cytidylyltransferase [EC:2.7.7.41] (A)"	Glycerophospholipid metabolism (ko00564);; Phosphatidylinositol signaling system (ko04070)	[I]	Lipid transport and metabolism	Cytidylyltransferase family	Phosphatidate cytidylyltransferase 1 GN=CDS1 OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: phosphatidate cytidylyltransferase 1 [Pteropus alecto]
ENSG00000163625(WDFY3)	--	4.770262676	1236	10.16261074	1284	5.411565971	1396	5.414659877	1399	5.295361321	1357	5.493121386	1424	0.973927624	0.147712296	normal	0.981143403	0.058282185	normal	0.983300504	0.020336949	normal	0.766323261	0.073151714	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; FYVE zinc finger;; PH domain associated with Beige/BEACH;; WD domain, G-beta repeat;; Concanavalin A-like lectin/glucanases superfamily"	WD repeat and FYVE domain-containing protein 3 GN=WDFY3 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: WD repeat and FYVE domain-containing protein 3 [Tupaia chinensis]
ENSG00000163626(COX18)	--	5.281616848	278	5.093203094	237	5.258579119	276	7.417320203	356	7.550140464	344	7.92044262	341	0.876478119	0.324372597	normal	0.484769528	0.513361682	normal	0.901749941	0.295353547	normal	0.132824849	0.375055568	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: protein insertion into membrane (GO:0051205);; 	K17797|0|ptr:461264|COX18; mitochondrial inner membrane protein COX18; K17797 mitochondrial inner membrane protein COX18 (A)	--	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	60Kd inner membrane protein	Mitochondrial inner membrane protein COX18 (Precursor) GN=COX18 OS=Homo sapiens (Human) PE=2 SV=1	OU	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial inner membrane protein COX18-like isoform X1 [Leptonychotes weddellii]
ENSG00000163629(PTPN13)	--	3.307067089	586	3.363263683	591	4.461566618	605	5.284390249	926	5.009346299	855	4.453027543	757	0.042987756	0.62795918	normal	0.333001433	0.51024857	normal	0.878762235	0.314362838	normal	0.003668298	0.488455542	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K02374|0|hsa:5783|PTPN13, FAP-1, PNP1, PTP-BAS, PTP-BL, PTP1E, PTPL1, PTPLE, hPTP1E; protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) (EC:3.1.3.48); K02374 tyrosine-protein phosphatase non-receptor type 13 (A)"	--	[T]	Signal transduction mechanisms	PDZ domain (Also known as DHR or GLGF);; Protein-tyrosine phosphatase;; FERM central domain;; PDZ domain;; FERM N-terminal domain;; FERM C-terminal PH-like domain	Tyrosine-protein phosphatase non-receptor type 13 GN=PTPN13 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 13 [Pteropus alecto]
ENSG00000163631(ALB)	--	0	0	0	0	0	0	0	0	0.040019921	0	0.04083176	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular space (GO:0005615);; 	"K16141|0|hsa:213|ALB, ANALBA, FDAH, PRO0883, PRO0903, PRO1341; albumin; K16141 serum albumin (A)"	--	--	--	"Serum albumin family;; Vitamin D binding protein, domain III"	Serum albumin (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: serum albumin isoform X2 [Panthera tigris altaica]
ENSG00000163633(C4orf36)	--	1.9051418	84	1.55572902	107	2.379949216	109	2.095126	114	1.063536389	65	2.844021001	178	0.905402215	0.403386365	normal	0.468293522	-0.727199284	normal	0.245192484	0.691676022	normal	0.802027024	0.23127429	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF4522)	Uncharacterized protein C4orf36 GN=C4orf36 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C4orf36 homolog [Oryctolagus cuniculus] 
ENSG00000163634(THOC7)	--	31.59630358	500	37.37417328	579	35.949193	561	42.30353	686	37.16889993	578	35.71651	554	0.651451656	0.424331036	normal	0.97238859	-0.023858046	normal	0.972666001	-0.026334798	normal	0.625739872	0.126811645	normal	--	--	Cellular Component: THO complex part of transcription export complex (GO:0000445);; Biological Process: mRNA processing (GO:0006397);; 	K13176|3.01349e-125|pps:100978758|THOC7; THO complex 7 homolog (Drosophila); K13176 THO complex subunit 7 (A)	RNA transport (ko03013)	[S]	Function unknown	Tho complex subunit 7	THO complex subunit 7 homolog GN=THOC7 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	THO complex subunit 7 homolog [Bos taurus] 
ENSG00000163635(ATXN7)	--	3.863326333	464	4.372823761	474	4.33384125	527	3.711221003	431	3.848691883	463	4.878707066	506	0.961196798	-0.136799035	normal	0.969020467	-0.05512347	normal	0.970163505	-0.066761487	normal	0.77952704	-0.085965015	normal	--	--	--	K11318|0|nle:100587199|ATXN7; ataxin 7; K11318 ataxin-7 (A)	--	[B]	Chromatin structure and dynamics	"SCA7, zinc-binding domain"	Ataxin-7 GN=ATXN7 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: ataxin-7 isoform 1 [Ceratotherium simum simum]
ENSG00000163636(PSMD6)	--	41.03417022	972	40.15675996	957	40.2458692	963	48.98800876	1165	52.47894554	1228	37.74630102	893	0.949087356	0.230136849	normal	0.862837652	0.337820842	normal	0.972929783	-0.116976251	normal	0.480747039	0.16241234	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K03037|0|hsa:9861|PSMD6, Rpn7, S10, SGA-113M, p42A, p44S10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 6; K03037 26S proteasome regulatory subunit N7 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	26S proteasome subunit RPN7;; PCI domain	26S proteasome non-ATPase regulatory subunit 6 GN=PSMD6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 6 isoform 1 [Ceratotherium simum simum]
ENSG00000163637(PRICKLE2)	--	1.658445604	258	1.54996411	244	1.39670092	225	2.878333135	434	5.033036932	781	3.38847464	524	0.02296436	0.71616961	normal	3.33E-16	1.650978302	up	5.28E-08	1.205883347	up	0.007042687	1.237599739	up	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	K04511|0|mcf:102129030|PRICKLE2; prickle homolog 2 (Drosophila); K04511 prickle (A)	Wnt signaling pathway (ko04310)	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	PET Domain;; LIM domain	Prickle-like protein 2 (Precursor) GN=PRICKLE2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: prickle-like protein 2 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000163638(ADAMTS9)	--	0.169355931	27	0.085411175	13	0.104727478	16	2.638195	420	4.829352229	762	4.192258055	654	0	3.854832378	up	0	5.697015746	up	0	5.218259459	up	1.93E-16	5.014935432	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	"K08624|0|hsa:56999|ADAMTS9; ADAM metallopeptidase with thrombospondin type 1 motif, 9; K08624 a disintegrin and metalloproteinase with thrombospondin motifs 9 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	GON domain;; Thrombospondin type 1 domain;; ADAM-TS Spacer 1;; Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 9 (Precursor) GN=ADAMTS9 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 9 [Equus caballus]
ENSG00000163644(PPM1K)	--	0.697666483	35	0.61718297	30	0.81493355	24	1.053125693	90	0.865664936	61	1.030265395	41	0.006375228	1.29508406	up	0.459793668	0.967572057	normal	0.909954481	0.728789395	normal	0.071107153	1.085190862	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K17505|0|ptr:461368|PPM1K; protein phosphatase, Mg2+/Mn2+ dependent, 1K; K17505 protein phosphatase 1K [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C;; Protein phosphatase 2C	"Protein phosphatase 1K, mitochondrial (Precursor) GN=PPM1K OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: protein phosphatase 1K, mitochondrial isoform 1 [Odobenus rosmarus divergens] "
ENSG00000163645(ERICH6)	--	0.099332196	4	0.233313104	4	0.473937142	4	0.178041069	1	0.0719633	2	0.0244455	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM194 protein	Glutamate-rich protein 6 GN=ERICH6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: glutamate-rich protein 6 [Ailuropoda melanoleuca]
ENSG00000163655(GMPS)	--	45.57948027	2764	43.9985103	2706	45.05140032	2779	43.50320054	2813	40.68040046	2775	29.30505082	2035	0.989681065	-0.005477309	normal	0.98920188	0.014891156	normal	0.563263629	-0.457536302	normal	0.553535676	-0.135878913	normal	[F]	Nucleotide transport and metabolism	Molecular Function: GMP synthase (glutamine-hydrolyzing) activity (GO:0003922);; Molecular Function: asparagine synthase (glutamine-hydrolyzing) activity (GO:0004066);; Molecular Function: ATP binding (GO:0005524);; Biological Process: purine nucleotide biosynthetic process (GO:0006164);; Biological Process: GMP biosynthetic process (GO:0006177);; Biological Process: asparagine biosynthetic process (GO:0006529);; Biological Process: glutamine metabolic process (GO:0006541);; Molecular Function: hydrolase activity (GO:0016787);; 	K01951|0|ggo:101133381|GMPS; GMP synthase [glutamine-hydrolyzing] isoform 1; K01951 GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] (A)	Purine metabolism (ko00230);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Glutamine amidotransferase class-I;; GMP synthase C terminal domain;; Peptidase C26;; NAD synthase;; Queuosine biosynthesis protein QueC;; Asparagine synthase;; tRNA methyl transferase;; PP-loop family	GMP synthase [glutamine-hydrolyzing] GN=GMPS OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: GMP synthase [glutamine-hydrolyzing] isoform 2 [Odobenus rosmarus divergens]
ENSG00000163659(TIPARP)	--	37.8337288	2467	31.96705192	2061	28.10395047	1848	25.35402085	1660	21.4571754	1392	14.66425034	1012	0.05567689	-0.60194641	normal	0.089032541	-0.587084066	normal	3.06E-05	-0.876063171	normal	0.012712717	-0.672687703	normal	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15259|0|hsa:25976|TIPARP, ARTD14, PARP7, pART14; TCDD-inducible poly(ADP-ribose) polymerase (EC:2.4.2.30); K15259 poly [ADP-ribose] polymerase 7/11/12/13 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain	TCDD-inducible poly [ADP-ribose] polymerase GN=TIPARP OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: TCDD-inducible poly [ADP-ribose] polymerase [Sus scrofa]
ENSG00000163660(CCNL1)	--	20.7738971	1352	21.716663	1400	15.84386523	1075	20.7989094	1445	19.21877304	1307	27.022469	1733	0.981909009	0.065070545	normal	0.97727757	-0.120459537	normal	0.009118919	0.67988327	normal	0.458892999	0.207774072	normal	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	Cellular Component: nucleus (GO:0005634);; 	--	--	[R]	General function prediction only	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain;; Transcription factor TFIIB repeat"	Cyclin-L1 GN=CCNL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-L1-like isoform X1 [Physeter catodon]
ENSG00000163661(PTX3)	--	2.93658	98	2.36732	81	3.75064	127	1.06426	36	0.698621	23	1.73278	58	0.000508066	-1.436895422	down	6.52E-05	-1.771673144	down	0.005096723	-1.118784127	down	0.000802022	-1.406097941	down	--	--	--	--	--	--	--	Pentaxin family;; Concanavalin A-like lectin/glucanases superfamily	Pentraxin-related protein PTX3 (Precursor) GN=PTX3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: pentraxin-related protein PTX3 [Odobenus rosmarus divergens]
ENSG00000163666(HESX1)	--	0.251796244	5	0.115529658	2	0.170096577	2	0.202940779	3	0.381981998	3	0.20256364	3	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K09354|6.05618e-136|hsa:8820|HESX1, ANF, CPHD5, RPX; HESX homeobox 1; K09354 homeobox protein expressed in ES cells 1 (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[R]	General function prediction only	Homeobox domain	Homeobox expressed in ES cells 1 GN=HESX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox expressed in ES cells 1 [Canis lupus familiaris]
ENSG00000163673(DCLK3)	--	0	0	0	0	0	0	0	0	0.016721923	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K17530|0|hsa:85443|DCLK3, CLR, DCAMKL3, DCDC3C, DCK3; doublecortin-like kinase 3 (EC:2.7.11.1); K17530 doublecortin-like kinase 3 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Doublecortin	Serine/threonine-protein kinase DCLK3 GN=DCLK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase DCLK3 [Pteropus alecto]
ENSG00000163681(SLMAP)	--	9.579020513	941	10.25688389	1032	10.15870483	1012	12.25825475	1201	10.30868962	1056	11.91495861	1180	0.881298923	0.32067286	normal	0.979542245	0.011723324	normal	0.956165457	0.212991103	normal	0.358453951	0.182146579	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	FHA domain;; Prefoldin subunit	Sarcolemmal membrane-associated protein GN=SLMAP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: sarcolemmal membrane-associated protein isoform X5 [Canis lupus familiaris]
ENSG00000163682(RPL9)	--	851.4228915	8091	789.7456	7596	754.948991	7314	907.161197	8833	875.47394	8289	852.9959042	8265	0.994804588	0.095735824	normal	0.994125976	0.104511677	normal	0.991645976	0.168030049	normal	0.599377817	0.120878328	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; Molecular Function: rRNA binding (GO:0019843);; 	K02940|4.8312e-128|ssc:100627537|RPL9; ribosomal protein L9; K02940 large subunit ribosomal protein L9e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L6	60S ribosomal protein L9 GN=RPL9P9 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L9 [Vicugna pacos]
ENSG00000163683(SMIM14)	--	12.28465527	896	10.08165023	817	9.656622291	732	9.897450823	960	13.27334159	996	10.79312769	999	0.976814243	0.068589775	normal	0.928669305	0.263940015	normal	0.585170452	0.439569218	normal	0.17700908	0.252015393	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2615)	Small integral membrane protein 14 GN=SMIM14 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 14 [Orycteropus afer afer]
ENSG00000163684(RPP14)	--	9.407999476	464	6.76004106	416	7.46054519	446	10.69993001	541	10.633153	555	8.605112491	464	0.950819938	0.190088196	normal	0.754809001	0.393236241	normal	0.969871901	0.048627989	normal	0.376220128	0.212925511	normal	--	--	Molecular Function: ribonuclease activity (GO:0004540);; Biological Process: tRNA processing (GO:0008033);; 	K14529|1.24406e-85|ptr:104001098|RPP14; ribonuclease P/MRP 14kDa subunit; K14529 ribonuclease P protein subunit RPP14 [EC:3.1.26.5] (A)	RNA transport (ko03013)	--	--	Rpp14/Pop5 family	Ribonuclease P protein subunit p14 GN=RPP14 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribonuclease P protein subunit p14 isoform X2 [Ursus maritimus]
ENSG00000163686(ABHD6)	--	8.917897376	405	7.404365174	323	7.739796737	351	4.582960607	206	4.807874864	203	4.708605214	209	5.42E-05	-1.000679743	down	0.073872723	-0.687382988	normal	0.019270455	-0.752012973	normal	0.000115912	-0.825183898	normal	[R]	General function prediction only	--	K13700|0|pps:100991016|ABHD6; abhydrolase domain containing 6; K13700 abhydrolase domain-containing protein 6 [EC:3.1.1.23] (A)	Retrograde endocannabinoid signaling (ko04723)	[R]	General function prediction only	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Ndr family;; Dienelactone hydrolase family	Monoacylglycerol lipase ABHD6 GN=ABHD6 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: monoacylglycerol lipase ABHD6 [Galeopterus variegatus]
ENSG00000163687(DNASE1L3)	--	0	0	0.224017111	1	0.081563631	1	0.039872182	1	0.119749556	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K11995|0|ptr:460477|DNASE1L3; deoxyribonuclease I-like 3; K11995 deoxyribonuclease-1-like protein [EC:3.1.21.-] (A)	--	--	--	Endonuclease/Exonuclease/phosphatase family	Deoxyribonuclease gamma (Precursor) GN=DNASE1L3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: deoxyribonuclease gamma isoform 1 [Ceratotherium simum simum]
ENSG00000163689(C3orf67)	--	3.365204439	76	2.601394749	73	3.98017536	91	2.307847013	63	2.044447975	61	2.971617702	86	0.958135426	-0.294920138	normal	0.959930901	-0.274288512	normal	0.970491555	-0.088311429	normal	0.723241561	-0.212544931	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C3orf67 GN=C3orf67 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: uncharacterized protein C3orf67 homolog isoform 1 [Dasypus novemcinctus]
ENSG00000163694(RBM47)	--	25.28795808	1778	27.82555014	1774	24.38260525	1772	34.41552809	2351	35.143093	2076	38.3220561	2604	0.831075711	0.371906701	normal	0.969447648	0.20521203	normal	0.17458069	0.546672232	normal	0.013341579	0.380275756	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 47 GN=RBM47 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: RNA-binding protein 47 isoform X1 [Capra hircus] 
ENSG00000163697(APBB2)	--	6.372099135	623	6.162246802	487	6.0040306	587	5.381649256	477	5.80804367	542	6.645283272	434	0.68368873	-0.414901778	normal	0.962591823	0.132554215	normal	0.60477466	-0.442625506	normal	0.271392407	-0.245167122	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04530|0|hsa:323|APBB2, FE65L, FE65L1; amyloid beta (A4) precursor protein-binding, family B, member 2; K04530 amyloid beta (A4) precursor protein-binding, family B, member 2 (Fe65-like) (A)"	--	--	--	Phosphotyrosine interaction domain (PTB/PID);; WW domain;; Phosphotyrosine-binding domain	Amyloid beta A4 precursor protein-binding family B member 2 GN=APBB2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: amyloid beta A4 precursor protein-binding family B member 2 isoform 1 [Ceratotherium simum simum]
ENSG00000163701(IL17RE)	--	0.155258	7	0.27794	13	0.150099655	6	0.289377102	12	0.635217	18	0.065804445	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05168|0|mcc:698972|IL17RE; interleukin 17 receptor E; K05168 interleukin 17 receptor E (A)	--	--	--	Interleukin-17 receptor extracellular region;; SEFIR domain	Interleukin-17 receptor E (Precursor) GN=IL17RE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-17 receptor E isoform X1 [Myotis lucifugus]
ENSG00000163702(IL17RC)	--	11.60064385	451	9.431721565	347	9.082314859	366	9.665635738	380	10.6953081	413	10.27266473	403	0.910216455	-0.276930936	normal	0.935302795	0.228864359	normal	0.961132587	0.130132156	normal	0.970629192	0.018048921	normal	--	--	--	K05166|0|ptr:460159|IL17RC; interleukin 17 receptor C; K05166 interleukin 17 receptor C (A)	--	--	--	Interleukin-17 receptor extracellular region;; SEFIR domain	Interleukin-17 receptor C (Precursor) GN=IL17RC OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-17 receptor C isoform X1 [Myotis lucifugus]
ENSG00000163703(CRELD1)	--	10.199815	369	7.12634	272	7.632267	295	7.30998	262	7.523111	269	7.239762	258	0.417458822	-0.522291371	normal	0.965791332	-0.037218952	normal	0.946092584	-0.20053518	normal	0.339702192	-0.26777825	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[S]	Function unknown	TLR4 regulator and MIR-interacting MSAP;; Calcium-binding EGF domain	Cysteine-rich with EGF-like domain protein 1 (Precursor) GN=CRELD1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	hypothetical protein PANDA_014506 [Ailuropoda melanoleuca]
ENSG00000163704(PRRT3)	--	1.87588	131	1.3464333	92	2.01391	144	1.54498	107	1.5855947	108	1.62995	115	0.929170073	-0.318644814	normal	0.958128093	0.206759532	normal	0.920270712	-0.328853417	normal	0.731059998	-0.17374752	normal	--	--	--	--	--	--	--	--	Proline-rich transmembrane protein 3 (Precursor) GN=PRRT3 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: proline-rich transmembrane protein 3 [Leptonychotes weddellii]
ENSG00000163705(FANCD2OS)	--	0	0	0	0	0.0629799	0	0.133825	2	0	0	0.066475193	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4563)	FANCD2 opposite strand protein GN=FANCD2OS OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: FANCD2 opposite strand protein [Eptesicus fuscus]
ENSG00000163710(PCOLCE2)	--	13.73840235	459	13.494898	454	13.71500038	461	10.63480309	358	9.346129	308	8.607873	284	0.770639116	-0.387892235	normal	0.204868715	-0.578831929	normal	0.024487292	-0.704194784	normal	0.006465203	-0.554281927	normal	--	--	--	--	--	--	--	CUB domain;; UNC-6/NTR/C345C module;; CUB-like domain	Procollagen C-endopeptidase enhancer 2 (Precursor) GN=PCOLCE2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: procollagen C-endopeptidase enhancer 2 [Dasypus novemcinctus]
ENSG00000163714(U2SURP)	--	38.6933121	2839	34.0660149	2578	35.090759	2702	36.29802868	2805	36.29103242	2913	31.5852749	2353	0.989291069	-0.048188105	normal	0.982888501	0.154741447	normal	0.973884901	-0.207693122	normal	0.913836245	-0.030174873	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; 	K12842|0|pps:100972098|U2SURP; U2 snRNP-associated SURP domain containing; K12842 U2-associated protein SR140 (A)	Spliceosome (ko03040)	[R]	General function prediction only	"Surp module;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; cwf21 domain"	U2 snRNP-associated SURP motif-containing protein GN=U2SURP OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U2 snRNP-associated SURP motif-containing protein isoform X2 [Equus caballus]
ENSG00000163719(MTMR14)	--	16.16975544	717	15.14693708	681	15.27179557	700	14.54104417	658	15.473512	678	18.82308387	848	0.963098228	-0.154372332	normal	0.974165625	-0.027734358	normal	0.922260835	0.267891316	normal	0.907234378	0.037532965	normal	--	--	--	"K18086|0|hsa:64419|MTMR14, C3orf29; myotubularin related protein 14; K18086 myotubularin-related protein 14 [EC:3.1.3.-] (A)"	--	--	--	--	Myotubularin-related protein 14 GN=MTMR14 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: myotubularin-related protein 14 isoform X1 [Galeopterus variegatus]
ENSG00000163728(TTC14)	--	14.36812036	861	17.38777	1124	16.732824	882	15.7137	829	15.866155	841	17.22949	929	0.974553032	-0.085318222	normal	0.602015359	-0.439205107	normal	0.976718097	0.066497394	normal	0.506931134	-0.162703674	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 14 GN=TTC14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 14 isoform X1 [Oryctolagus cuniculus]
ENSG00000163735(CXCL5)	--	139.211	4612	124.197	4165	121.498	3991	778.94	26247	541.705	17921	980.093	32541	0	2.477465789	up	0	2.083438975	up	0	3.018667199	up	1.67E-07	2.566062343	up	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K05506|8.56864e-53|hsa:6374|CXCL5, ENA-78, SCYB5; chemokine (C-X-C motif) ligand 5; K05506 C-X-C motif chemokine 5/6 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; TNF signaling pathway (ko04668);; Pertussis (ko05133);; Rheumatoid arthritis (ko05323)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	ENA-78(9-78) (Precursor) GN=CXCL5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: C-X-C motif chemokine 6 [Equus przewalskii]
ENSG00000163736(PPBP)	--	0	0	0	0	0	0	0.29813	3	0.204232	1	0.913602	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K10029|1.98255e-68|hsa:5473|PPBP, B-TG1, Beta-TG, CTAP-III, CTAP3, CTAPIII, CXCL7, LA-PF4, LDGF, MDGF, NAP-2, PBP, SCYB7, TC1, TC2, TGB, TGB1, THBGB, THBGB1; pro-platelet basic protein (chemokine (C-X-C motif) ligand 7); K10029 platelet basic protein (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	Neutrophil-activating peptide 2(1-63) (Precursor) GN=PPBP OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: platelet basic protein [Trichechus manatus latirostris]
ENSG00000163737(PF4)	--	0.810413	5	0.631608	4	0.762954	4	0.746669	5	1.57107	9	0.944394	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K05407|7.29284e-51|hsa:5196|PF4, CXCL4, PF-4, SCYB4; platelet factor 4; K05407 platelet factor 4 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	"Platelet factor 4, short form (Precursor) GN=PF4 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: platelet factor 4-like [Galeopterus variegatus]
ENSG00000163738(MTHFD2L)	--	10.75519522	204	8.33189542	166	9.099740994	185	8.860218453	190	9.881285	210	8.92919715	196	0.960027347	-0.132368647	normal	0.905503642	0.315221305	normal	0.965028857	0.074445643	normal	0.864496211	0.081817966	normal	[H]	Coenzyme transport and metabolism	Molecular Function: methylenetetrahydrofolate dehydrogenase (NADP+) activity (GO:0004488);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13403|0|hsa:441024|MTHFD2L; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like (EC:3.5.4.9 1.5.1.15); K13403 methylenetetrahydrofolate dehydrogenase(NAD+) / 5,10-methenyltetrahydrofolate cyclohydrolase [EC:1.5.1.15 3.5.4.9] (A)"	One carbon pool by folate (ko00670)	[H]	Coenzyme transport and metabolism	"Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain;; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain"	Methenyltetrahydrofolate cyclohydrolase GN=MTHFD2L OS=Homo sapiens (Human) PE=2 SV=3	H	Coenzyme transport and metabolism	PREDICTED: probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2 [Ceratotherium simum simum]
ENSG00000163739(CXCL1)	--	43.5342	695	49.264	788	32.6328	523	138.127	2264	120.38	1921	197.153	3184	0	1.670794099	up	2.68E-11	1.262561582	up	0	2.594199403	up	1.32E-05	1.856330214	up	--	--	--	"K05505|3.23051e-50|ptr:740567|CXCL1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); K05505 C-X-C motif chemokine 1/2/3 (A)"	Chemokine signaling pathway (ko04062);; TNF signaling pathway (ko04668);; Salmonella infection (ko05132);; Legionellosis (ko05134);; Amoebiasis (ko05146);; Rheumatoid arthritis (ko05323)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	GRO-alpha(6-73) (Precursor) GN=CXCL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: growth-regulated protein homolog-like [Myotis brandtii]
ENSG00000163743(RCHY1)	--	3.337184	137	5.4188862	171	5.489163158	163	7.573593	185	5.528223928	159	6.560519	182	0.854542469	0.398657564	normal	0.960508077	-0.12524709	normal	0.95884559	0.149462152	normal	0.75865949	0.138086477	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10144|0|pon:100446564|RCHY1; ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase; K10144 RING finger and CHY zinc finger domain-containing protein 1 [EC:6.3.2.19] (A)"	p53 signaling pathway (ko04115);; Ubiquitin mediated proteolysis (ko04120);; Measles (ko05162)	[R]	General function prediction only	"Zinc-ribbon;; CHY zinc finger;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger and CHY zinc finger domain-containing protein 1 GN=RCHY1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger and CHY zinc finger domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000163746(PLSCR2)	--	0	0	0.220017255	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Scramblase	Phospholipid scramblase 2 GN=PLSCR2 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: phospholipid scramblase 1-like [Tupaia chinensis]
ENSG00000163749(CCDC158)	--	0.0113987	1	0	0	0.0113186	0	0	0	0.0220369	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 158 GN=CCDC158 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 158 [Ceratotherium simum simum]
ENSG00000163754(GYG1)	--	24.03101825	736	27.06449038	827	26.98248585	818	26.16392742	807	22.27784153	679	25.36402267	773	0.971943773	0.101827603	normal	0.891659189	-0.305285077	normal	0.973535108	-0.08975315	normal	0.704918661	-0.097221027	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	K00750|0|ptr:460765|GYG1; glycogenin 1; K00750 glycogenin glucosyltransferase [EC:2.4.1.186] (A)	--	[G]	Carbohydrate transport and metabolism	Glycosyl transferase family 8	Glycogenin-1 GN=GYG1 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: glycogenin-1 isoform X3 [Canis lupus familiaris]
ENSG00000163755(HPS3)	--	34.709545	2257	30.636912	2052	30.758424	2078	24.039043	1563	18.505338	1232	20.26486	1356	0.130415653	-0.560459556	normal	0.001412274	-0.756727026	normal	0.034233856	-0.623563761	normal	4.68E-06	-0.643447228	normal	--	--	--	--	--	--	--	"Hermansky-Pudlak syndrome 3, C-terminal;; Hermansky-Pudlak syndrome 3, middle region;; Hermansky-Pudlak syndrome 3"	Hermansky-Pudlak syndrome 3 protein GN=HPS3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: Hermansky-Pudlak syndrome 3 protein isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000163762(TM4SF18)	--	18.20182	587	21.59229	755	19.51176567	667	36.14825843	1148	30.2119625	1013	37.64308	1207	1.02E-05	0.935077089	normal	0.722694689	0.401961745	normal	0.000135536	0.845929282	normal	1.35E-06	0.724254313	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	L6 membrane protein	Transmembrane 4 L6 family member 18 GN=TM4SF18 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane 4 L6 family member 18 isoform 2 [Dasypus novemcinctus]
ENSG00000163781(TOPBP1)	--	15.557313	1647	17.1862572	1783	16.97736905	1734	14.891574	1570	14.39605814	1498	13.99437454	1443	0.98156451	-0.099812875	normal	0.940038024	-0.272443165	normal	0.937825739	-0.273062593	normal	0.228028686	-0.21648402	normal	--	--	--	"K10728|0|hsa:11073|TOPBP1, TOP2BP1; topoisomerase (DNA) II binding protein 1; K10728 topoisomerase (DNA) II binding protein 1 (A)"	--	[L]	"Replication, recombination and repair"	BRCA1 C Terminus (BRCT) domain;; twin BRCT domain	DNA topoisomerase 2-binding protein 1 GN=TOPBP1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: DNA topoisomerase 2-binding protein 1 [Vicugna pacos]
ENSG00000163785(RYK)	--	20.58207	974	20.82717175	975	19.45364	908	21.98626	1033	20.40892	955	27.91562	1328	0.978486149	0.053931702	normal	0.977670168	-0.051247725	normal	0.189987177	0.539452243	normal	0.479077091	0.194346991	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05128|0|hsa:6259|RYK, D3S3195, JTK5, JTK5A, RYK1; receptor-like tyrosine kinase (EC:2.7.10.1); K05128 RYK receptor-like tyrosine kinase [EC:2.7.10.1] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; WIF domain;; Protein kinase domain	Tyrosine-protein kinase RYK (Precursor) GN=RYK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase RYK isoform 1 [Orcinus orca]
ENSG00000163788(SNRK)	--	2.637880937	236	3.49166209	324	2.6646909	245	2.692160468	250	3.413617121	312	2.803042698	252	0.965998442	0.051980168	normal	0.964647395	-0.075515125	normal	0.9667693	0.032154836	normal	0.997384872	-0.005312379	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08802|0|hsa:54861|SNRK, HSNFRK; SNF related kinase (EC:2.7.11.1); K08802 SNF related kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	SNF-related serine/threonine-protein kinase OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SNF-related serine/threonine-protein kinase isoform 1 [Ceratotherium simum simum] 
ENSG00000163794(UCN)	--	2.99974	28	3.59168	35	2.39629	23	1.90005	18	2.88382	27	3.80453	36	0.967040744	-0.62514561	normal	0.973834378	-0.377212897	normal	0.953468494	0.605989568	normal	0.927934945	-0.106145514	normal	--	--	--	--	--	--	--	Corticotropin-releasing factor family	Urocortin (Precursor) GN=UCN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: urocortin [Orcinus orca] 
ENSG00000163795(ZNF513)	--	10.758921	426	9.055092	385	8.296267	337	6.120102	247	8.297942	333	8.746009	350	0.003209302	-0.813271465	normal	0.934864197	-0.229791281	normal	0.967732218	0.046111833	normal	0.194604233	-0.324232208	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; C2H2-type zinc-finger domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 513 GN=ZNF513 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 513 [Balaenoptera acutorostrata scammoni]
ENSG00000163798(SLC4A1AP)	--	13.257031	844	14.14284	911	14.535741	930	13.3213815	847	13.0630499	832	12.56658133	786	0.977333093	-0.025666652	normal	0.966604845	-0.152029884	normal	0.934883807	-0.250549116	normal	0.518929093	-0.144647211	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	FHA domain;; Double-stranded RNA binding motif	Kanadaptin GN=SLC4A1AP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"PREDICTED: LOW QUALITY PROTEIN: kanadaptin, partial [Sus scrofa]"
ENSG00000163803(PLB1)	--	0.121370518	11	0.398443968	29	0.358059963	25	0.255244693	21	0.251641965	19	0.350426014	25	0.968616014	0.818238804	normal	0.965549167	-0.59300776	normal	0.986690324	-0.007818491	normal	1	-0.020473792	normal	--	--	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	"K14621|0|ptr:459117|PLB1; phospholipase B1; K14621 phospholipase B1, membrane-associated [EC:3.1.1.4 3.1.1.5] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; Vitamin digestion and absorption (ko04977)	[I]	Lipid transport and metabolism	GDSL-like Lipase/Acylhydrolase;; GDSL-like Lipase/Acylhydrolase family	Lysophospholipase (Precursor) GN=PLB1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	"PREDICTED: phospholipase B1, membrane-associated [Physeter catodon]"
ENSG00000163806(SPDYA)	--	0.076545547	2	0.151166135	3	0.109822	2	0	0	0.19666487	4	0.130331654	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K08694|0|ptr:459119|SPDYA; speedy/RINGO cell cycle regulator family member A; K08694 speedy (A)	Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914)	--	--	Cell cycle regulatory protein	Speedy protein A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: speedy protein A isoform X2 [Camelus dromedarius]
ENSG00000163807(KIAA1143)	--	10.2871	839	12.9059	1043	11.2982	901	13.2493	1090	11.5042	940	12.0848	992	0.840867618	0.346195622	normal	0.965072486	-0.171171475	normal	0.971581613	0.130313051	normal	0.686138746	0.097207662	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4604)	Uncharacterized protein KIAA1143 GN=KIAA1143 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA1143 homolog [Chrysochloris asiatica]
ENSG00000163808(KIF15)	--	3.847165872	442	3.767643588	403	4.623723823	499	4.06253148	466	3.099879	351	2.859230308	327	0.969878535	0.045297968	normal	0.938702268	-0.219850526	normal	0.101522093	-0.615717984	normal	0.335875802	-0.254480388	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10400|0|hsa:56992|KIF15, HKLP2, KNSL7, NY-BR-62; kinesin family member 15; K10400 kinesin family member 15 (A)"	--	--	--	Kinesin motor domain;; Kinesin motor	Kinesin-like protein KIF15 GN=KIF15 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF15 [Camelus dromedarius]
ENSG00000163810(TGM4)	--	0.0144062	1	0.057808	4	0.0285527	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein-glutamine gamma-glutamyltransferase activity (GO:0003810);; Biological Process: peptide cross-linking (GO:0018149);; 	"K05621|0|hsa:7047|TGM4, TGP, hTGP; transglutaminase 4 (EC:2.3.2.13); K05621 transglutaminase 4 [EC:2.3.2.13] (A)"	--	--	--	"Transglutaminase family;; Transglutaminase family, C-terminal ig like domain;; Transglutaminase-like superfamily"	Protein-glutamine gamma-glutamyltransferase 4 GN=TGM4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-glutamine gamma-glutamyltransferase 4 [Galeopterus variegatus]
ENSG00000163811(WDR43)	--	40.32717319	2569	41.61441041	2654	39.71094623	2420	33.08390155	2098	37.32578416	2373	28.28263468	1802	0.912002469	-0.322810399	normal	0.978199251	-0.182772617	normal	0.651574006	-0.433384448	normal	0.058098318	-0.306641445	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14546|0|hsa:23160|WDR43, NET12, UTP5; WD repeat domain 43; K14546 U3 small nucleolar RNA-associated protein 5 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	"WD domain, G-beta repeat;; Dip2/Utp12 Family"	WD repeat-containing protein 43 GN=WDR43 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: WD repeat-containing protein 43 [Tupaia chinensis]
ENSG00000163812(ZDHHC3)	--	20.08255238	1094	20.28238604	1095	21.77862279	1113	25.76800617	1348	23.41691197	1267	21.58446152	1191	0.931683563	0.270033358	normal	0.964203697	0.188816504	normal	0.978261554	0.08931105	normal	0.346641363	0.183401604	normal	[R]	General function prediction only	--	K18932|0|mcf:101925351|hypothetical protein; K18932 palmitoyltransferase [EC:2.3.1.225] (A)	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC3 GN=ZDHHC3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	Palmitoyltransferase ZDHHC3 [Bos mutus]
ENSG00000163814(CDCP1)	--	39.966005	4644	31.80790817	3691	38.954385	4500	39.7981122	4623	25.329084	2927	29.682606	3394	0.992824645	-0.037358485	normal	0.895395976	-0.355851412	normal	0.781211109	-0.415068707	normal	0.458762106	-0.25211931	normal	--	--	--	"K06732|0|hsa:64866|CDCP1, CD318, SIMA135, TRASK; CUB domain containing protein 1; K06732 CUB domain-containing protein 1 (A)"	--	--	--	CUB domain	CUB domain-containing protein 1 (Precursor) GN=CDCP1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: CUB domain-containing protein 1 [Felis catus]
ENSG00000163818(LZTFL1)	--	3.467942543	211	4.215597968	253	3.97239535	235	3.803440289	234	3.923542423	239	6.048940046	367	0.961233127	0.117619775	normal	0.961501807	-0.102920247	normal	0.126320923	0.631549664	normal	0.588737545	0.245238947	normal	--	--	--	--	--	--	--	Leucine zipper	Leucine zipper transcription factor-like protein 1 GN=LZTFL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: leucine zipper transcription factor-like protein 1 [Orcinus orca]
ENSG00000163820(FYCO1)	--	6.0247322	1038	6.004792669	1121	6.34285097	1150	4.9665531	862	4.31435093	821	5.525174	928	0.901967193	-0.298393406	normal	0.480001652	-0.470014527	normal	0.884931607	-0.317263216	normal	0.02923802	-0.362689427	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	FYVE zinc finger;; RUN domain	FYVE and coiled-coil domain-containing protein 1 GN=FYCO1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: FYVE and coiled-coil domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000163823(CCR1)	--	0	0	0	0	0	0	0.0219058	1	0.0213925	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04176|0|ggo:101150910|CCR1; c-C chemokine receptor type 1; K04176 C-C chemokine receptor type 1 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	C-C chemokine receptor type 1 GN=CCR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: c-C chemokine receptor type 1-like [Pantholops hodgsonii]
ENSG00000163832(ELP6)	--	13.67387572	266	12.76106185	279	13.7760038	299	12.80605454	262	14.29243061	280	16.29064112	342	0.966155678	-0.052386798	normal	0.96640088	-0.016177324	normal	0.949931318	0.184685395	normal	0.913514069	0.046569862	normal	--	--	Cellular Component: Elongator holoenzyme complex (GO:0033588);; 	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2348)	Elongator complex protein 6 GN=ELP6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: elongator complex protein 6 [Galeopterus variegatus]
ENSG00000163840(DTX3L)	--	4.2677145	466	4.48103	486	5.78094	621	7.535311479	823	6.43986	701	8.372630007	916	0.001275804	0.787751511	normal	0.369574239	0.505714612	normal	0.17355468	0.551350626	normal	0.003189128	0.612911138	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K06058|0|hsa:151636|DTX3L, BBAP; deltex 3 like, E3 ubiquitin ligase; K06058 deltex (A)"	Notch signaling pathway (ko04330)	--	--	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase DTX3L GN=DTX3L OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase DTX3L [Galeopterus variegatus]
ENSG00000163848(ZNF148)	--	8.821111185	862	10.87641315	944	8.330669654	862	9.326000353	861	10.28754824	878	8.955895223	889	0.977398964	-0.032449025	normal	0.971114241	-0.125783475	normal	0.977568871	0.03614167	normal	0.884742977	-0.042980447	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 148 GN=ZNF148 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	zinc finger protein 148 [Bos taurus] 
ENSG00000163864(NMNAT3)	--	1.802042401	57	1.2638288	40	1.851581738	49	1.039341861	27	1.381174017	38	0.863964002	23	0.346720669	-1.06612641	normal	0.980180326	-0.091863311	normal	0.523548473	-1.051040791	normal	0.181467214	-0.751681908	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; Biological Process: biosynthetic process (GO:0009058);; 	K06210|0|pps:100985370|NMNAT3; nicotinamide nucleotide adenylyltransferase 3; K06210 nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] (A)	Nicotinate and nicotinamide metabolism (ko00760)	[H]	Coenzyme transport and metabolism	Cytidylyltransferase	Nicotinamide mononucleotide adenylyltransferase 3 GN=NMNAT3 OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: nicotinamide mononucleotide adenylyltransferase 3 isoform X2 [Tupaia chinensis]
ENSG00000163866(SMIM12)	--	13.11422709	372	15.96093517	459	11.05764478	377	17.21804107	531	16.3326297	486	15.74366413	435	0.485707049	0.480906835	normal	0.968794199	0.060840786	normal	0.947236046	0.197421614	normal	0.308411638	0.243416893	normal	--	--	--	--	--	--	--	--	Small integral membrane protein 12 GN=SMIM12 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: small integral membrane protein 12 isoform X1 [Myotis davidii]
ENSG00000163867(ZMYM6)	--	5.61076253	281	4.822052756	270	5.69741643	282	5.85611811	318	6.282658424	359	5.43782581	312	0.957301191	0.146869186	normal	0.795602852	0.387708992	normal	0.95893465	0.136861393	normal	0.43411182	0.226530482	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	MYM-type Zinc finger with FCS sequence motif;; Domain of unknown function (DUF4371)	Zinc finger MYM-type protein 6 GN=ZMYM6 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger MYM-type protein 6 isoform X1 [Panthera tigris altaica] 
ENSG00000163870(TPRA1)	--	24.8905868	704	23.0559502	668	19.78420121	582	30.81281715	871	31.33366598	887	50.64200651	1442	0.916699697	0.275723224	normal	0.760224288	0.386897068	normal	6.93E-12	1.298472091	up	0.126949749	0.691691869	normal	--	--	--	--	--	[S]	Function unknown	Predicted membrane protein	Transmembrane protein adipocyte-associated 1 GN=TPRA1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein adipocyte-associated 1 [Ceratotherium simum simum]
ENSG00000163872(YEATS2)	--	7.774490572	1101	11.56552305	1430	10.65784755	1297	8.307483141	1124	6.62972336	965	7.76347857	1035	0.980772774	-0.001003311	normal	0.08877897	-0.588078551	normal	0.867910777	-0.333403012	normal	0.072403061	-0.314706789	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	YEATS family	YEATS domain-containing protein 2 GN=YEATS2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: YEATS domain-containing protein 2 isoform X2 [Myotis brandtii] 
ENSG00000163874(ZC3H12A)	--	7.873458	408	6.619522	368	5.659048886	316	19.930151	1086	17.658243	941	19.319078	1065	1.09E-12	1.378247275	up	3.56E-11	1.329523558	up	0	1.739750437	up	1.33E-22	1.479924796	up	--	--	--	"K18668|0|hsa:80149|ZC3H12A, MCPIP, MCPIP1, dJ423B22.1; zinc finger CCCH-type containing 12A; K18668 ribonuclease ZC3H12 [EC:3.1.-.-] (A)"	--	[S]	Function unknown	Zc3h12a-like Ribonuclease NYN domain	Ribonuclease ZC3H12A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ribonuclease ZC3H12A [Ceratotherium simum simum]
ENSG00000163875(MEAF6)	--	19.54272783	466	19.83740231	481	20.583301	494	19.21970839	449	16.04232527	402	19.8633815	471	0.967586903	-0.084164042	normal	0.908588416	-0.279305905	normal	0.968789568	-0.076834508	normal	0.595231857	-0.145375866	normal	--	--	Cellular Component: histone acetyltransferase complex (GO:0000123);; Biological Process: histone acetylation (GO:0016573);; 	K11344|8.11066e-97|ptr:456758|MEAF6; MYST/Esa1-associated factor 6; K11344 chromatin modification-related protein EAF6 (A)	--	[S]	Function unknown	Histone acetyltransferase subunit NuA4	Chromatin modification-related protein MEAF6 GN=MEAF6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: chromatin modification-related protein MEAF6 isoform 1 [Odobenus rosmarus divergens]
ENSG00000163877(SNIP1)	--	3.8837	298	3.51714	275	3.20662	247	3.6046	280	3.8384	294	3.79736	292	0.961002138	-0.120078905	normal	0.964165109	0.074561385	normal	0.936522749	0.23185886	normal	0.891306603	0.057458413	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13108|0|hsa:79753|SNIP1, PMRED; Smad nuclear interacting protein 1; K13108 smad nuclear-interacting protein 1 (A)"	--	[T]	Signal transduction mechanisms	FHA domain	Smad nuclear-interacting protein 1 GN=SNIP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: smad nuclear-interacting protein 1 [Galeopterus variegatus]
ENSG00000163879(DNALI1)	--	0.0415954	2	0.0615992	3	0.0203343	0	0.020573	1	0.100777	4	0.0204987	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10410|0|ptr:456760|DNALI1; dynein, axonemal, light intermediate chain 1; K10410 dynein light intermediate chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	Axonemal dynein light chain	Axonemal dynein light intermediate polypeptide 1 GN=DNALI1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: axonemal dynein light intermediate polypeptide 1 [Tupaia chinensis]
ENSG00000163882(POLR2H)	--	29.79974186	593	28.1777722	580	31.6109463	637	27.16684247	581	27.34868786	534	27.30733049	497	0.97181827	-0.060168702	normal	0.962330935	-0.140258441	normal	0.80234008	-0.365354364	normal	0.42212313	-0.188650573	normal	--	--	"Biological Process: transcription, DNA-templated (GO:0006351);; "	"K03016|2.89397e-114|hsa:5437|POLR2H, RPABC3, RPB17, RPB8; polymerase (RNA) II (DNA directed) polypeptide H (EC:2.7.7.6); K03016 DNA-directed RNA polymerases I, II, and III subunit RPABC3 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpb8	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 GN=POLR2H OS=Homo sapiens (Human) PE=1 SV=4"	K	Transcription	"PREDICTED: DNA-directed RNA polymerases I, II, and III subunit RPABC3 isoform X1 [Erinaceus europaeus]"
ENSG00000163884(KLF15)	--	0	0	0.0592804	3	0	0	0	0	0.0197926	0	0.0603312	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09210|0|hsa:28999|KLF15, KKLF; Kruppel-like factor 15; K09210 krueppel-like factor 15 (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 15 GN=KLF15 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: Krueppel-like factor 15 isoform X2 [Myotis lucifugus]
ENSG00000163888(CAMK2N2)	--	2.67653	46	1.99346	35	1.78075	32	1.9386	34	2.37927	41	0.954812	17	0.959591697	-0.449401845	normal	0.978075847	0.198896096	normal	0.910482554	-0.863972674	normal	0.68301153	-0.319587082	normal	--	--	--	--	--	--	--	Calcium/calmodulin-dependent protein kinase II inhibitor	Calcium/calmodulin-dependent protein kinase II inhibitor 2 GN=CAMK2N2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase II inhibitor 2 [Monodelphis domestica]
ENSG00000163898(LIPH)	--	9.379991602	657	10.65950782	674	9.344117998	659	11.2737903	614	7.90378358	561	9.116225385	645	0.966349104	-0.128176817	normal	0.906117896	-0.285471173	normal	0.974032925	-0.039179863	normal	0.536301206	-0.14993753	normal	--	--	--	--	--	--	--	Lipase	Lipase member H (Precursor) GN=LIPH OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lipase member H isoform X1 [Galeopterus variegatus]
ENSG00000163900(TMEM41A)	--	10.17600788	448	9.372980435	413	9.376328138	403	12.29249206	523	12.9199112	564	10.25411068	450	0.949976946	0.191870497	normal	0.668638769	0.426784677	normal	0.958637194	0.150319665	normal	0.254743346	0.260476639	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	SNARE associated Golgi protein	Transmembrane protein 41A (Precursor) GN=TMEM41A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 41A [Equus przewalskii]
ENSG00000163902(RPN1)	--	89.84210623	4154	89.1014059	4185	84.146875	3933	105.221769	4905	104.337912	4792	111.14715	5168	0.982553676	0.208848509	normal	0.986457785	0.173914963	normal	0.864508518	0.385554728	normal	0.14562846	0.255397069	normal	--	--	Molecular Function: dolichyl-diphosphooligosaccharide-protein glycotransferase activity (GO:0004579);; Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: protein glycosylation (GO:0006486);; Cellular Component: integral component of membrane (GO:0016021);; 	"K12666|0|hsa:6184|RPN1, OST1, RBPH1; ribophorin I (EC:2.4.99.18); K12666 oligosaccharyltransferase complex subunit alpha (ribophorin I) (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ribophorin I	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Precursor) GN=RPN1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 [Mustela putorius furo] 
ENSG00000163904(SENP2)	--	4.469445412	463	4.501764292	465	5.490311862	493	5.915554265	585	5.4286731	559	5.701973965	528	0.885894533	0.305688052	normal	0.93048992	0.243467993	normal	0.968259262	0.09039087	normal	0.362667182	0.213282112	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K03345|0|hsa:59343|SENP2, AXAM2, SMT3IP2; SUMO1/sentrin/SMT3 specific peptidase 2 (EC:3.4.22.68); K03345 sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68] (A)"	RNA transport (ko03013);; Wnt signaling pathway (ko04310)	--	--	"Ulp1 protease family, C-terminal catalytic domain"	Sentrin-specific protease 2 GN=SENP2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	Sentrin-specific protease 2 [Pteropus alecto]
ENSG00000163909(HEYL)	--	2.551281	221	1.9397486	164	2.1177	180	1.858944869	148	1.687029102	145	1.728672004	145	0.355535219	-0.604111815	normal	0.951402101	-0.197134752	normal	0.913282397	-0.317259659	normal	0.243420553	-0.388627722	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09091|0|hsa:26508|HEYL, HESR3, HEY3, HRT3, bHLHb33; hes-related family bHLH transcription factor with YRPW motif-like; K09091 hairy and enhancer of split related with YRPW motif (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain;; Hairy Orange	Hairy/enhancer-of-split related with YRPW motif-like protein GN=HEYL OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: hairy/enhancer-of-split related with YRPW motif-like protein [Odobenus rosmarus divergens]
ENSG00000163913(IFT122)	--	7.019193539	534	5.598031552	428	7.32611114	579	6.696699787	521	7.045053647	507	7.185121024	542	0.970305148	-0.0661958	normal	0.938990331	0.222226252	normal	0.968026736	-0.10328306	normal	0.991325506	0.00619723	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Coatomer WD associated region"	Intraflagellar transport protein 122 homolog GN=IFT122 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: intraflagellar transport protein 122 homolog isoform X2 [Equus przewalskii]
ENSG00000163914(RHO)	--	0.0223472	1	0.0220908	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04250|0|mcf:102128424|RHO, opsin; rhodopsin; K04250 rhodopsin (A)"	Phototransduction (ko04744)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Amino terminal of the G-protein receptor rhodopsin;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srw;; Serpentine type 7TM GPCR chemoreceptor Srsx	Rhodopsin GN=RHO OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	rhodopsin [Felis catus] 
ENSG00000163918(RFC4)	--	22.4911335	482	22.627505	431	31.05849	651	25.861418	492	22.3318934	418	21.320196	413	0.971470943	-0.001203298	normal	0.967495418	-0.065378532	normal	0.030507249	-0.662856908	normal	0.436464399	-0.262510069	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K10755|0|hsa:5984|RFC4, A1, RFC37; replication factor C (activator 1) 4, 37kDa; K10755 replication factor C subunit 2/4 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430)	[L]	"Replication, recombination and repair"	"ATPase family associated with various cellular activities (AAA);; Replication factor C C-terminal domain;; DNA polymerase III, delta subunit;; Rad17 cell cycle checkpoint protein;; Part of AAA domain;; Protein of unknown function (DUF815)"	Replication factor C subunit 4 GN=RFC4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: replication factor C subunit 4 [Pteropus alecto]
ENSG00000163923(RPL39L)	--	30.36767043	303	31.4265408	325	32.92394026	343	26.64046137	286	22.13254528	222	22.07464232	226	0.96181541	-0.113542166	normal	0.322033993	-0.568087589	normal	0.191650372	-0.60685666	normal	0.083934082	-0.425548421	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L39 protein	60S ribosomal protein L39-like GN=RPL39L OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L39-like [Myotis brandtii]
ENSG00000163930(BAP1)	--	15.74013429	1028	23.91213393	1190	18.09599458	1130	16.35369152	1107	19.34801415	1161	20.30700834	1193	0.978121295	0.075873406	normal	0.979831942	-0.056946888	normal	0.979559087	0.06988879	normal	0.929798672	0.026940554	normal	--	--	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Cellular Component: intracellular (GO:0005622);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; 	"K08588|0|hsa:8314|BAP1, HUCEP-13, UCHL2; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) (EC:3.4.19.12); K08588 ubiquitin carboxyl-terminal hydrolase BAP1 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ubiquitin carboxyl-terminal hydrolase, family 1"	Ubiquitin carboxyl-terminal hydrolase BAP1 GN=BAP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase BAP1 [Lipotes vexillifer]
ENSG00000163931(TKT)	--	814.6455633	33423	950.3323542	39159	835.7210156	35049	558.793351	22918	643.712037	26066	746.5868726	31045	0.349879975	-0.575160207	normal	0.241711061	-0.608572252	normal	0.997169369	-0.183295384	normal	0.019458791	-0.44786545	normal	[G]	Carbohydrate transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624);; "	"K00615|0|hsa:7086|TKT, HEL107, TK, TKT1; transketolase (EC:2.2.1.1); K00615 transketolase [EC:2.2.1.1] (A)"	Pentose phosphate pathway (ko00030);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	"Transketolase, thiamine diphosphate binding domain;; Transketolase, pyrimidine binding domain;; Transketolase, C-terminal domain;; Dehydrogenase E1 component;; 1-deoxy-D-xylulose-5-phosphate synthase"	Transketolase GN=TKT OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: transketolase isoform X1 [Condylura cristata]
ENSG00000163932(PRKCD)	--	6.961467122	414	4.73638213	265	6.503716465	392	6.55880165	390	5.767983774	343	4.066096207	241	0.963149607	-0.116543175	normal	0.852469484	0.349034646	normal	0.033060447	-0.706600493	normal	0.763057888	-0.159159316	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K06068|0|hsa:5580|PRKCD, ALPS3, CVID9, MAY1, PKCD, nPKC-delta; protein kinase C, delta (EC:2.7.10.2 2.7.11.13); K06068 novel protein kinase C delta type [EC:2.7.11.13] (A)"	Chemokine signaling pathway (ko04062);; Vascular smooth muscle contraction (ko04270);; Tight junction (ko04530);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Neurotrophin signaling pathway (ko04722);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Type II diabetes mellitus (ko04930)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Protein kinase C terminal domain	Protein kinase C delta type catalytic subunit GN=PRKCD OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein kinase C delta type [Tupaia chinensis] 
ENSG00000163933(RFT1)	--	23.18430956	592	19.53576018	540	21.49867232	587	25.62265154	706	24.80382303	673	19.30256692	530	0.942815047	0.222708949	normal	0.897568987	0.295478029	normal	0.960414482	-0.155238486	normal	0.611299089	0.129345309	normal	--	--	Molecular Function: lipid transporter activity (GO:0005319);; Biological Process: lipid transport (GO:0006869);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06316|0|hsa:91869|RFT1, CDG1N; RFT1 homolog (S. cerevisiae); K06316 oligosaccharide translocation protein RFT1 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Rft protein	Protein RFT1 homolog GN=RFT1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: protein RFT1 homolog [Equus przewalskii]
ENSG00000163935(SFMBT1)	--	3.958434529	385	4.390168095	414	4.629265895	370	4.00793258	420	3.525519137	417	3.4461588	359	0.965562472	0.094338113	normal	0.969189507	-0.010970015	normal	0.967895974	-0.051618671	normal	0.983948554	0.011173535	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	mbt repeat;; Protein of unknown function (DUF3588);; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Scm-like with four MBT domains protein 1 GN=SFMBT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: scm-like with four MBT domains protein 1 isoform X1 [Ursus maritimus] 
ENSG00000163938(GNL3)	--	34.164937	1450	33.352353	1416	31.617288	1329	32.891921	1392	36.20666	1523	25.244145	1070	0.980771125	-0.089629009	normal	0.981160377	0.083582036	normal	0.885844673	-0.320614318	normal	0.728501727	-0.096035066	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K14538|0|hsa:26354|GNL3, C77032, E2IG3, NNP47, NS; guanine nucleotide binding protein-like 3 (nucleolar); K14538 nuclear GTP-binding protein (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[R]	General function prediction only	GNL3L/Grn1 putative GTPase;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B;; Elongation factor Tu GTP binding domain	Guanine nucleotide-binding protein-like 3 GN=GNL3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: guanine nucleotide-binding protein-like 3 isoform X2 [Equus przewalskii]
ENSG00000163939(PBRM1)	--	6.248249594	932	10.235657	1140	8.545702494	1068	6.953783292	1056	7.307065824	1022	8.390382988	1147	0.969428745	0.149144631	normal	0.964928957	-0.178814502	normal	0.977374797	0.094533113	normal	0.959389613	0.017584867	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: chromatin binding (GO:0003682);; Molecular Function: protein binding (GO:0005515);; 	K11757|0|ptr:460430|PBRM1; polybromo 1; K11757 protein polybromo-1 (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	Bromodomain;; BAH domain;; HMG (high mobility group) box;; HMG-box domain	Protein polybromo-1 GN=PBRM1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein polybromo-1 isoform X6 [Mustela putorius furo] 
ENSG00000163945(UVSSA)	--	3.546388592	604	4.162119142	621	3.484499895	594	3.086519904	513	3.222008975	554	3.379729234	594	0.91857263	-0.265687626	normal	0.953450795	-0.185654858	normal	0.973620955	-0.008270386	normal	0.541412629	-0.15189113	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2043)	UV-stimulated scaffold protein A GN=UVSSA OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UV-stimulated scaffold protein A [Tupaia chinensis]
ENSG00000163946(FAM208A)	--	13.9691469	1807	13.57023495	1789	15.5258701	2031	12.79590884	1752	12.51039239	1703	12.2949653	1663	0.984117421	-0.075360914	normal	0.982655714	-0.092421424	normal	0.926477703	-0.296449144	normal	0.420566859	-0.157906768	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3715)	Protein FAM208A GN=FAM208A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM208A isoform 2 [Canis lupus familiaris]
ENSG00000163947(ARHGEF3)	--	7.71499979	391	8.447232369	386	5.966863426	375	4.7774251	266	5.705407536	321	5.107187674	283	0.211522228	-0.583774504	normal	0.905112708	-0.286222443	normal	0.740201238	-0.41245874	normal	0.06364225	-0.426039264	normal	[T]	Signal transduction mechanisms	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Pleckstrin homology domain	Rho guanine nucleotide exchange factor 3 GN=ARHGEF3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 3 isoform X1 [Ursus maritimus]
ENSG00000163950(SLBP)	--	36.33669991	1219	32.38179088	1106	33.56394553	1135	34.89728905	1196	36.27774056	1227	25.53373548	860	0.980515308	-0.05823889	normal	0.974354508	0.128190841	normal	0.696054072	-0.407948651	normal	0.740304548	-0.097811866	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K18710|2.44784e-146|nle:100585696|SLBP; stem-loop binding protein; K18710 histone RNA hairpin-binding protein (A)	--	[A]	RNA processing and modification	Histone RNA hairpin-binding protein RNA-binding domain	Histone RNA hairpin-binding protein GN=SLBP OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: histone RNA hairpin-binding protein isoform 4 [Canis lupus familiaris]
ENSG00000163956(LRPAP1)	--	12.82787	1597	14.10932	1794	12.915183	1633	12.00256	1503	12.44246	1550	13.345896	1664	0.979621006	-0.118234284	normal	0.958828468	-0.232127495	normal	0.984936164	0.018821933	normal	0.605720556	-0.111940672	normal	--	--	Cellular Component: endoplasmic reticulum (GO:0005783);; Molecular Function: heparin binding (GO:0008201);; Molecular Function: low-density lipoprotein particle receptor binding (GO:0050750);; 	--	--	[OUTIV]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms;; Lipid transport and metabolism;; Defense mechanisms"	"Alpha-2-macroglobulin RAP, C-terminal domain;; Alpha-2-macroglobulin RAP, N-terminal domain"	Alpha-2-macroglobulin receptor-associated protein (Precursor) GN=LRPAP1 OS=Homo sapiens (Human) PE=1 SV=1	IOTUV	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport;; Defense mechanisms"	Alpha-2-macroglobulin receptor-associated protein [Tupaia chinensis]
ENSG00000163958(ZDHHC19)	--	0	0	0.0543194	1	0	0	0	0	0.106042	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18932|8.98725e-173|hsa:131540|ZDHHC19, DHHC19; zinc finger, DHHC-type containing 19 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC19 GN=ZDHHC19 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC19 isoform X1 [Felis catus]
ENSG00000163959(SLC51A)	--	0.2063744	3	0.48816	6	0.4356549	4	0.3201875	4	0.4324875	4	0.1600839	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K14360|0|hsa:200931|SLC51A, OSTA, OSTalpha; solute carrier family 51, alpha subunit; K14360 organic solute transporter subunit alpha (A)"	Bile secretion (ko04976)	--	--	Organic solute transporter Ostalpha	Organic solute transporter subunit alpha GN=SLC51A OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: organic solute transporter subunit alpha [Eptesicus fuscus]
ENSG00000163960(UBXN7)	--	4.227086443	717	5.24777269	829	4.813807821	803	4.85176045	831	4.637886877	784	4.619025917	744	0.958845931	0.181681236	normal	0.972062748	-0.101754095	normal	0.970335412	-0.118157564	normal	0.968639418	-0.015357637	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	UBX domain;; UBA-like domain;; Thioredoxin-like	UBX domain-containing protein 7 GN=UBXN7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: UBX domain-containing protein 7 [Trichechus manatus latirostris]
ENSG00000163961(RNF168)	--	3.513448904	365	3.260002103	344	3.717614066	384	4.108579614	430	3.949621	407	4.259865	442	0.944654324	0.204812976	normal	0.938533146	0.220302446	normal	0.948348452	0.193936187	normal	0.437183298	0.205747454	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF168 GN=RNF168 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF168 [Camelus dromedarius]
ENSG00000163964(PIGX)	--	54.18067301	2687	61.76623355	2802	60.80147565	2723	53.54954216	2742	52.941713	2464	48.81214255	2404	0.989478006	-0.001599109	normal	0.974727461	-0.206762158	normal	0.977824357	-0.187940363	normal	0.527798614	-0.131473202	normal	--	--	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: GPI anchor biosynthetic process (GO:0006506);; 	"K07541|8.93055e-172|hsa:54965|PIGX, PIG-X; phosphatidylinositol glycan anchor biosynthesis, class X; K07541 phosphatidylinositol glycan, class X (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	--	--	PIG-X / PBN1	Phosphatidylinositol-glycan biosynthesis class X protein (Precursor) GN=PIGX OS=Homo sapiens (Human) PE=2 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: phosphatidylinositol-glycan biosynthesis class X protein [Ceratotherium simum simum]
ENSG00000163975(MELTF)	--	42.64116	2604	45.38039	2520	36.32406999	2501	55.50373	3331	49.00566	3161	46.82251	2700	0.921772412	0.324224148	normal	0.937570407	0.30536682	normal	0.986612174	0.102103475	normal	0.148250192	0.24781513	normal	--	--	--	"K06569|0|hsa:4241|MFI2, CD228, MAP97, MTF1; antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5; K06569 melanoma-associated antigen p97 (A)"	--	--	--	"Transferrin;; ABC transporter, phosphonate, periplasmic substrate-binding protein"	Melanotransferrin (Precursor) GN=MFI2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: melanotransferrin [Lipotes vexillifer]
ENSG00000163993(S100P)	--	0.679598	16	0.335409	8	0.412107	9	0.333598	8	0.953436	22	1.17506	28	--	--	--	0.862770199	1.286516976	normal	0.55363922	1.481756515	normal	--	--	--	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-P GN=S100P OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein S100-P [Galeopterus variegatus]
ENSG00000163995(ABLIM2)	--	0.470254139	27	0.188559998	7	0.12743632	4	0.057712134	3	0.072878394	3	0.113955521	6	0.007840771	-2.677952497	down	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	"K07520|0|hsa:84448|ABLIM2; actin binding LIM protein family, member 2; K07520 actin-binding LIM protein (A)"	Axon guidance (ko04360)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain;; Villin headpiece domain	Actin-binding LIM protein 2 GN=ABLIM2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: actin-binding LIM protein 2 isoform X11 [Canis lupus familiaris]
ENSG00000164002(EXO5)	--	2.994461718	118	1.931348754	92	2.972956504	112	2.265355631	110	1.987547718	101	1.983780301	94	0.965286097	-0.13035708	normal	0.967035642	0.11147373	normal	0.951088275	-0.257260792	normal	0.874328069	-0.099754296	normal	--	--	Molecular Function: single-stranded DNA 5'-3' exodeoxyribonuclease activity (GO:0045145);; 	"K17815|0|hsa:64789|EXO5, C1orf176, DEM1, Exo_V, hExo5; exonuclease 5; K17815 exonuclease V [EC:3.1.-.-] (A)"	--	[S]	Function unknown	Exonuclease V - a 5' deoxyribonuclease;; PD-(D/E)XK nuclease superfamily	Exonuclease V GN=EXO5 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: exonuclease V isoform X2 [Felis catus]
ENSG00000164007(CLDN19)	--	0.036046807	1	0	0	0.017799223	0	0	0	0.017942807	0	0.018104528	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|2.00639e-148|pps:100996190|CLDN19; claudin 19; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-19 GN=CLDN19 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: claudin-19 [Tupaia chinensis]
ENSG00000164008(C1orf50)	--	2.441736055	100	2.838573887	118	3.83016528	119	3.218858149	116	3.063708415	115	3.068280699	122	0.961530492	0.180712978	normal	0.967313064	-0.057828787	normal	0.969031045	0.027285664	normal	0.9508736	0.04599959	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2452)	Uncharacterized protein C1orf50 GN=C1orf50 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C1orf50 homolog isoform X1 [Tupaia chinensis] 
ENSG00000164010(ERMAP)	--	2.559760262	170	3.028896614	202	2.657309711	173	2.762567203	184	2.925160694	191	3.888436185	256	0.964825255	0.082620932	normal	0.961827942	-0.101428163	normal	0.450742715	0.55308148	normal	0.616984096	0.191011178	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06712|0|hsa:114625|ERMAP, BTN5, PRO2801, RD, SC; erythroblast membrane-associated protein (Scianna blood group); K06712 butyrophilin (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPRY domain;; SPRY-associated domain;; Immunoglobulin V-set domain	Erythroid membrane-associated protein (Precursor) GN=ERMAP OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: erythroid membrane-associated protein [Galeopterus variegatus]
ENSG00000164011(ZNF691)	--	4.131532345	148	3.814323375	140	4.232576904	167	3.350267342	149	4.945662664	184	5.518728168	194	0.967833252	-0.020900864	normal	0.878122857	0.369362677	normal	0.948803326	0.206183316	normal	0.646851954	0.191852246	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 691 GN=ZNF691 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 691 [Galeopterus variegatus]
ENSG00000164022(AIMP1)	--	18.80967	799	22.74005336	939	21.27569002	821	21.46445904	897	19.547306	826	20.503847	853	0.969130273	0.135833614	normal	0.954034451	-0.206055811	normal	0.976681968	0.046787523	normal	0.976471761	-0.011952255	normal	[R]	General function prediction only	Molecular Function: tRNA binding (GO:0000049);; 	K15437|0|pps:100991364|AIMP1; aminoacyl tRNA synthetase complex-interacting multifunctional protein 1; K15437 aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Putative tRNA binding domain	Endothelial monocyte-activating polypeptide 2 GN=AIMP1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: aminoacyl tRNA synthase complex-interacting multifunctional protein 1 isoform X3 [Canis lupus familiaris]
ENSG00000164023(SGMS2)	--	4.289172808	397	8.231292786	514	5.311054294	466	8.04931343	750	6.117693055	537	6.618608541	607	0.000126081	0.884390033	normal	0.97081046	0.041607403	normal	0.790838908	0.372014382	normal	0.073873163	0.437906777	normal	--	--	--	K04714|0|pon:100446194|SGMS2; sphingomyelin synthase 2; K04714 shingomyelin synthase [EC:2.7.8.27] (A)	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[S]	Function unknown	PAP2 superfamily C-terminal;; PAP2 superfamily	Phosphatidylcholine:ceramide cholinephosphotransferase 2 GN=SGMS2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: phosphatidylcholine:ceramide cholinephosphotransferase 2 [Orcinus orca]
ENSG00000164024(METAP1)	--	29.70970091	1390	29.73762047	1395	31.443479	1448	32.04227835	1500	28.36029942	1304	25.79150422	1201	0.981595007	0.078961327	normal	0.977418875	-0.118614778	normal	0.929155604	-0.27779783	normal	0.654520284	-0.101695017	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K01265|0|hsa:23173|METAP1, MAP1A, MetAP1A; methionyl aminopeptidase 1 (EC:3.4.11.18); K01265 methionyl aminopeptidase [EC:3.4.11.18] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Metallopeptidase family M24	Methionine aminopeptidase 1 {ECO:0000255|HAMAP-Rule:MF_03174} GN=METAP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: methionine aminopeptidase 1 isoform X1 [Galeopterus variegatus]
ENSG00000164031(DNAJB14)	--	10.473079	854	14.08374	1036	10.39026594	845	11.82285	840	9.070132294	758	14.05673	855	0.97641888	-0.054579992	normal	0.475497928	-0.471372822	normal	0.977706033	0.008666218	normal	0.394800122	-0.178414774	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09520|0|pps:100973855|DNAJB14; DnaJ (Hsp40) homolog, subfamily B, member 14; K09520 DnaJ homolog subfamily B member 14 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF1977);; DnaJ domain	DnaJ homolog subfamily B member 14 GN=DNAJB14 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 14 [Odobenus rosmarus divergens]
ENSG00000164032(H2AFZ)	--	261.623	4065	285.685	4558	290.053	4597	340.927	5420	304.574	4727	299.839	4721	0.870547316	0.384079147	normal	0.992652419	0.031087254	normal	0.992899974	0.030098604	normal	0.47437796	0.147930789	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|6.73134e-73|fch:102055451|histone H2A.Z-like; K11251 histone H2A (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H2A.Z GN=H2AFZ OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_017927 [Ailuropoda melanoleuca] 
ENSG00000164035(EMCN)	--	0	0	0	0	0	0	0.044070813	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16664|1.3774e-129|ggo:101144313|EMCN; endomucin isoform 1; K16664 endomucin (A)	--	--	--	Endomucin	Endomucin (Precursor) GN=EMCN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: endomucin-like [Physeter catodon]
ENSG00000164037(SLC9B1)	--	0.099764529	2	0	0	0.319682	1	0.09712691	2	0.139983	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 9B1 GN=SLC9B1 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 9B1 [Galeopterus variegatus]
ENSG00000164038(SLC9B2)	--	3.306982215	147	2.926906295	131	3.5122923	162	3.517208779	158	3.075303369	134	3.473164621	152	0.966149995	0.07254472	normal	0.967236181	0.01111279	normal	0.964336084	-0.099257176	normal	0.996314771	-0.008019349	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Mitochondrial sodium/hydrogen exchanger 9B2 GN=SLC9B2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: mitochondrial sodium/hydrogen exchanger 9B2 [Galeopterus variegatus]
ENSG00000164039(BDH2)	--	8.721179044	195	6.307057	138	8.268042428	158	13.24329575	309	15.42896535	354	15.19089968	330	0.174063743	0.629330164	normal	4.76E-08	1.328242361	up	5.90E-05	1.047161553	up	7.92E-06	0.995111987	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00019|2.28579e-165|ptr:461412|BDH2; 3-hydroxybutyrate dehydrogenase, type 2; K00019 3-hydroxybutyrate dehydrogenase [EC:1.1.1.30] (A)"	Synthesis and degradation of ketone bodies (ko00072);; Butanoate metabolism (ko00650)	[R]	General function prediction only	Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase	3-hydroxybutyrate dehydrogenase type 2 GN=BDH2 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 3-hydroxybutyrate dehydrogenase type 2 isoform X1 [Camelus dromedarius] 
ENSG00000164040(PGRMC2)	--	48.98969965	1713	52.81185267	1821	50.07032428	1701	63.57399816	2150	58.91602193	2084	79.04026105	2564	0.927694931	0.296741261	normal	0.975875214	0.173063371	normal	0.085192068	0.583296409	normal	0.022628655	0.356153781	normal	--	--	--	"K17278|4.15692e-94|hsa:10424|PGRMC2, DG6, PMBP; progesterone receptor membrane component 2; K17278 membrane-associated progesterone receptor component (A)"	--	[R]	General function prediction only	Cytochrome b5-like Heme/Steroid binding domain	Membrane-associated progesterone receptor component 2 GN=PGRMC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: membrane-associated progesterone receptor component 2 [Chrysochloris asiatica]
ENSG00000164045(CDC25A)	--	4.92261565	355	4.91153867	362	5.242424388	384	5.44608635	395	5.72416021	385	4.3303798	298	0.961851678	0.122697798	normal	0.966287833	0.067170075	normal	0.812563004	-0.372415899	normal	0.893793623	-0.052293215	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Cellular Component: intracellular (GO:0005622);; Biological Process: protein dephosphorylation (GO:0006470);; Biological Process: positive regulation of cell cycle G2/M phase transition (GO:1902751);; 	"K06645|0|hsa:993|CDC25A, CDC25A2; cell division cycle 25A (EC:3.1.3.48); K06645 M-phase inducer phosphatase 1 [EC:3.1.3.48] (A)"	Cell cycle (ko04110);; Progesterone-mediated oocyte maturation (ko04914);; MicroRNAs in cancer (ko05206)	[D]	"Cell cycle control, cell division, chromosome partitioning"	M-phase inducer phosphatase;; Rhodanese-like domain	M-phase inducer phosphatase 1 GN=CDC25A OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: M-phase inducer phosphatase 1 isoform X1 [Equus przewalskii]
ENSG00000164048(ZNF589)	--	2.99114752	185	2.631856	184	2.595264	184	2.376034003	152	2.213427	163	1.741360163	133	0.914429856	-0.311427343	normal	0.95023494	-0.194560147	normal	0.757527641	-0.471987815	normal	0.357941178	-0.325289507	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:51385|ZNF589, SZF1; zinc finger protein 589; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 589 GN=ZNF589 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 589 isoform X2 [Galeopterus variegatus]
ENSG00000164050(PLXNB1)	--	4.233133845	660	4.667168558	732	4.2590889	680	4.682018425	723	5.705768	880	5.895949733	912	0.970683823	0.100473847	normal	0.937224105	0.243773454	normal	0.674078187	0.414409086	normal	0.182675431	0.259012274	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06821|0|hsa:5364|PLXNB1, PLEXIN-B1, PLXN5, SEP; plexin B1; K06821 plexin B (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; IPT/TIG domain;; Sema domain;; Plexin repeat	Plexin-B1 (Precursor) GN=PLXNB1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: plexin-B1 [Galeopterus variegatus]
ENSG00000164051(CCDC51)	--	11.56587987	334	11.327013	336	10.890992	332	13.1457171	382	15.93192186	450	12.42204732	355	0.955084158	0.162194263	normal	0.756837464	0.398482548	normal	0.96513912	0.087956828	normal	0.40302901	0.223129533	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 51 GN=CCDC51 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 51 [Ceratotherium simum simum]
ENSG00000164053(ATRIP)	--	13.65544068	404	11.72474918	370	12.46997229	433	10.71414307	419	10.94880184	379	8.922140671	306	0.969718838	0.021681722	normal	0.968279703	0.013192743	normal	0.432231478	-0.507009541	normal	0.608513742	-0.150563929	normal	--	--	--	K10905|0|ggo:101145767|ATRIP; ATR-interacting protein isoform 1; K10905 ATR interacting protein (A)	Fanconi anemia pathway (ko03460)	--	--	--	ATR-interacting protein GN=ATRIP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ATR-interacting protein isoform X3 [Equus przewalskii]
ENSG00000164054(SHISA5)	--	69.56218089	2262	69.03636435	2286	67.85370025	2269	83.90234031	2749	81.0514391	2658	83.31170132	2733	0.96147978	0.250321291	normal	0.97572119	0.195968826	normal	0.957643667	0.259979312	normal	0.176472657	0.234667845	normal	--	--	--	K10135|1.48252e-73|ggo:101148514|SHISA5; protein shisa-5; K10135 scotin (A)	p53 signaling pathway (ko04115)	--	--	Wnt and FGF inhibitory regulator	Protein shisa-5 (Precursor) GN=SHISA5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein shisa-5 isoform X1 [Equus caballus]
ENSG00000164056(SPRY1)	--	1.639962543	80	2.491195647	111	0.930609065	45	1.789907042	79	1.9020858	88	2.629902605	120	0.973092629	-0.048050932	normal	0.925073038	-0.351026487	normal	0.000228742	1.37731334	up	0.724807845	0.261097428	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	"K04704|0|hsa:10252|SPRY1, hSPRY1; sprouty homolog 1, antagonist of FGF signaling (Drosophila); K04704 protein sprouty homolog 1 (A)"	Jak-STAT signaling pathway (ko04630)	--	--	Sprouty protein (Spry)	Protein sprouty homolog 1 GN=SPRY1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein sprouty homolog 1 [Echinops telfairi]
ENSG00000164061(BSN)	--	0.196406	71	0.25287503	91	0.143422204	52	0.087713961	31	0.09051744	33	0.102268211	37	0.065140023	-1.186426463	normal	0.000938086	-1.44331689	down	0.946694062	-0.482562867	normal	0.014513231	-1.104696588	normal	--	--	Cellular Component: synapse (GO:0045202);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	Piccolo Zn-finger	Protein bassoon GN=BSN OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: protein bassoon [Galeopterus variegatus]
ENSG00000164062(APEH)	--	32.37511685	1510	25.843512	1296	26.45830951	1338	28.12015808	1319	29.41772414	1409	23.73073269	1172	0.957085119	-0.225690298	normal	0.979114344	0.099068447	normal	0.9629683	-0.199156286	normal	0.624874209	-0.109069085	normal	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01303|0|hsa:327|APEH, AARE, ACPH, APH, D3F15S2, D3S48E, DNF15S2, OPH; acylaminoacyl-peptide hydrolase (EC:3.4.19.1); K01303 acylaminoacyl-peptidase [EC:3.4.19.1] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prolyl oligopeptidase family;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Dienelactone hydrolase family;; alpha/beta hydrolase fold	Acylamino-acid-releasing enzyme GN=APEH OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: acylamino-acid-releasing enzyme [Galeopterus variegatus]
ENSG00000164066(INTU)	--	1.051460769	222	1.310912182	273	1.093534473	222	0.998209719	211	1.24411912	253	1.136365463	218	0.962658258	-0.103414665	normal	0.958491166	-0.1304393	normal	0.966549975	-0.034287277	normal	0.822459709	-0.093443297	normal	--	--	--	--	--	--	--	--	Protein inturned GN=INTU OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein inturned [Ursus maritimus]
ENSG00000164068(RNF123)	--	6.451518365	566	6.795219075	566	6.407245718	573	5.362379741	417	6.018900393	488	6.873986994	556	0.510035363	-0.470093692	normal	0.934919493	-0.234671467	normal	0.971929555	-0.051603431	normal	0.273071578	-0.243104708	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12169|0|hsa:63891|RNF123, KPC1; ring finger protein 123; K12169 Kip1 ubiquitination-promoting complex protein 1 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF123 GN=RNF123 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF123 [Galeopterus variegatus]
ENSG00000164070(HSPA4L)	--	10.91684292	1089	13.29185287	1246	16.01749462	1431	16.60518208	1567	11.14918154	1026	12.29575664	1194	0.359327769	0.493585608	normal	0.906675091	-0.301296182	normal	0.934557038	-0.269200377	normal	0.984600345	-0.013855714	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	"K09485|0|hsa:22824|HSPA4L, APG-1, HSPH3, Osp94; heat shock 70kDa protein 4-like; K09485 heat shock protein 110kDa (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein	Heat shock 70 kDa protein 4L GN=HSPA4L OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 4L isoform X1 [Oryctolagus cuniculus]
ENSG00000164073(MFSD8)	--	6.05027167	316	5.99426	316	4.787264193	299	4.944469837	260	4.256640388	250	5.159503011	273	0.891794446	-0.310577261	normal	0.846283926	-0.357494654	normal	0.958576188	-0.138800995	normal	0.333454191	-0.270930738	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K12307|0|hsa:256471|MFSD8, CLN7; major facilitator superfamily domain containing 8; K12307 MFS transporter, ceroid-lipofuscinosis neuronal protein 7 (A)"	Lysosome (ko04142)	[R]	General function prediction only	Major Facilitator Superfamily;; Sugar (and other) transporter	Major facilitator superfamily domain-containing protein 8 GN=MFSD8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: major facilitator superfamily domain-containing protein 8 [Pantholops hodgsonii]
ENSG00000164074(ABHD18)	--	3.047869363	191	3.23061697	174	2.788694864	194	4.405732927	224	3.523198017	214	3.550838353	206	0.948928991	0.197624761	normal	0.924477221	0.274939015	normal	0.964727689	0.077708323	normal	0.629022553	0.182898891	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2048);; Alpha/beta hydrolase family	Uncharacterized protein C4orf29 (Precursor) GN=C4orf29 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C4orf29 homolog [Leptonychotes weddellii]
ENSG00000164076(CAMKV)	--	0.1816907	11	0	0	0.129815856	6	0.098113986	3	0.130830764	7	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08812|0|hsa:79012|CAMKV, 1G5, VACAMKL; CaM kinase-like vesicle-associated; K08812 CaM kinase-like vesicle-associated [EC:2.7.11.-] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	CaM kinase-like vesicle-associated protein GN=CAMKV OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: caM kinase-like vesicle-associated protein isoform X1 [Equus przewalskii]
ENSG00000164077(MON1A)	--	3.38458	115	3.35979	125	2.36605	89	3.32921	118	3.18305	103	3.29605	116	0.969634143	0.006238456	normal	0.936086953	-0.296748419	normal	0.918518129	0.368457228	normal	0.990301572	0.012835084	normal	--	--	--	--	--	[S]	Function unknown	Trafficking protein Mon1	Vacuolar fusion protein MON1 homolog A GN=MON1A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: vacuolar fusion protein MON1 homolog A [Felis catus]
ENSG00000164078(MST1R)	--	4.97933298	327	4.405598471	347	3.852547086	326	3.6727505	269	3.429186494	282	3.460648172	238	0.890392899	-0.310903048	normal	0.88154328	-0.319121183	normal	0.648744989	-0.459695484	normal	0.148769039	-0.363465269	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05100|0|pps:100982426|MST1R; macrophage stimulating 1 receptor (c-met-related tyrosine kinase); K05100 macrophage-stimulating 1 receptor [EC:2.7.10.1] (A)	--	[T]	Signal transduction mechanisms	Sema domain;; Protein tyrosine kinase;; Protein kinase domain;; IPT/TIG domain	Macrophage-stimulating protein receptor beta chain (Precursor) GN=MST1R OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: macrophage-stimulating protein receptor isoform X1 [Galeopterus variegatus]
ENSG00000164080(RAD54L2)	--	32.8392122	1309	33.79696448	1321	34.00607392	1334	31.5026533	1265	33.7653305	1497	38.56817792	1526	0.980172438	-0.080064371	normal	0.97302116	0.158846291	normal	0.96864899	0.185508092	normal	0.690903071	0.09278037	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K10876|0|hsa:23132|RAD54L2, ARIP4, HSPC325, SRISNF2L; RAD54-like 2 (S. cerevisiae) (EC:3.6.4.12); K10876 RAD54-like protein 2 [EC:3.6.4.12] (A)"	--	[R]	General function prediction only	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Helicase ARIP4 GN=RAD54L2 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: helicase ARIP4 isoform X7 [Canis lupus familiaris]
ENSG00000164082(GRM2)	--	0	0	0	0	0.0191329	0	0	0	0	0	0.027086345	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04605|0|hsa:2912|GRM2, GLUR2, GPRC1B, MGLUR2, mGlu2; glutamate receptor, metabotropic 2; K04605 metabotropic glutamate receptor 2/3 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724);; Cocaine addiction (ko05030)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Nine Cysteines Domain of family 3 GPCR	Metabotropic glutamate receptor 2 (Precursor) GN=GRM2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: metabotropic glutamate receptor 2 [Oryctolagus cuniculus]
ENSG00000164086(DUSP7)	--	3.41195	186	3.1570296	174	3.150477	176	7.340628	400	6.967374	382	3.8108764	210	1.31E-05	1.067712833	up	8.27E-06	1.106408751	up	0.937382639	0.244596102	normal	0.051945354	0.865255849	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K04459|0|ptr:470826|DUSP7; dual specificity phosphatase 7; K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 7 GN=DUSP7 OS=Homo sapiens (Human) PE=1 SV=4	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 7 [Condylura cristata]
ENSG00000164087(POC1A)	--	11.324309	446	9.084262	375	12.193812	490	9.93861	394	8.173246	326	8.416325	341	0.943572329	-0.208913983	normal	0.937631609	-0.222481973	normal	0.326420889	-0.529332119	normal	0.157621517	-0.326584273	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	K16482|0|pps:100987912|POC1A; POC1 centriolar protein A; K16482 centriolar protein POC1 (A)	--	--	--	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A;; Nucleoporin Nup120/160"	POC1 centriolar protein homolog A GN=POC1A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: POC1 centriolar protein homolog A isoform X1 [Camelus ferus]
ENSG00000164088(PPM1M)	--	3.465017414	162	2.74232412	135	3.672231084	175	2.554141844	124	3.811413725	152	3.26053213	147	0.855745889	-0.41200459	normal	0.959382873	0.14812098	normal	0.937775205	-0.257400023	normal	0.687901536	-0.178419726	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	K17507|0|ggo:101154405|PPM1M; protein phosphatase 1M isoform 1; K17507 protein phosphatase 1M [EC:3.1.3.16] (A)	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C;; Stage II sporulation protein E (SpoIIE);; Protein phosphatase 2C	Protein phosphatase 1M GN=PPM1M OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1M [Ceratotherium simum simum]
ENSG00000164089(ETNPPL)	--	0.260234338	9	0.167904307	7	0.240808459	6	0.143200416	6	0.046706676	1	0.095550833	4	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: transaminase activity (GO:0008483);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K14286|0|ptr:461428|ETNPPL, AGXT2L1; ethanolamine-phosphate phospho-lyase; K14286 ethanolamine-phosphate phospho-lyase [EC:4.2.3.2] (A)"	Glycerophospholipid metabolism (ko00564)	[R]	General function prediction only	Aminotransferase class-III	Ethanolamine-phosphate phospho-lyase GN=ETNPPL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ethanolamine-phosphate phospho-lyase isoform X2 [Galeopterus variegatus]
ENSG00000164091(WDR82)	--	25.366188	1900	25.89590779	1964	27.00792696	1987	32.781397	2458	35.290518	2625	33.220289	2487	0.887625359	0.340410659	normal	0.791423951	0.396830804	normal	0.917743139	0.315308264	normal	0.025096621	0.350534288	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14962|0|ssc:100522703|WDR82, WDR82P1; WD repeat domain 82; K14962 COMPASS component SWD2 (A)"	mRNA surveillance pathway (ko03015)	[ABO]	"RNA processing and modification;; Chromatin structure and dynamics;; Posttranslational modification, protein turnover, chaperones"	"WD domain, G-beta repeat"	WD repeat-containing protein 82 GN=WDR82 OS=Homo sapiens (Human) PE=1 SV=1	ABO	"RNA processing and modification;; Chromatin structure and dynamics;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: WD repeat-containing protein 82 [Physeter catodon] 
ENSG00000164093(PITX2)	--	2.211460281	78	1.673062407	59	1.807202044	66	2.289650009	80	2.84985737	103	2.581134629	92	0.973570873	0.005584987	normal	0.418637257	0.767368727	normal	0.898029433	0.461874307	normal	0.387253657	0.41725235	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K04686|0|ptr:461438|PITX2; paired-like homeodomain 2; K04686 paired-like homeodomain transcription factor 2 (A)	TGF-beta signaling pathway (ko04350)	[K]	Transcription	Homeobox domain;; OAR domain	Pituitary homeobox 2 GN=PITX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: pituitary homeobox 2 isoform X1 [Echinops telfairi]
ENSG00000164096(C4orf3)	--	21.80623	787	23.57346	796	23.94492	790	27.2307	822	11.95217	469	24.44132	736	0.976597826	0.031881593	normal	0.001837658	-0.782646154	normal	0.971060666	-0.110219681	normal	0.458762106	-0.249173755	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C4orf3 GN=C4orf3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C4orf3 homolog [Orycteropus afer afer]
ENSG00000164099(PRSS12)	--	1.9917667	134	1.442394637	93	1.115882212	81	1.662382001	124	2.16669645	145	1.512514902	118	0.962858518	-0.141043382	normal	0.563355267	0.611303286	normal	0.797316968	0.526315067	normal	0.482516868	0.307686506	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K09624|0|hsa:8492|PRSS12, BSSP-3, BSSP3, MRT1; protease, serine, 12 (neurotrypsin, motopsin); K09624 protease, serine, 12 (neurotrypsin, motopsin) [EC:3.4.21.-] (A)"	--	--	--	Scavenger receptor cysteine-rich domain;; Trypsin;; Scavenger receptor cysteine-rich domain;; Kringle domain	Neurotrypsin (Precursor) GN=PRSS12 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: neurotrypsin [Felis catus]
ENSG00000164100(NDST3)	--	0	0	0	0	0	0	0.0199185	2	0.0193435	1	0.0198111	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Molecular Function: [heparan sulfate]-glucosamine N-sulfotransferase activity (GO:0015016);; Molecular Function: hydrolase activity (GO:0016787);; 	"K02578|0|hsa:9348|NDST3, HSST3; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 (EC:2.8.2.8); K02578 heparan sulfate N-deacetylase/N-sulfotransferase NDST3 [EC:3.1.1.- 2.8.2.-] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	heparan sulfate-N-deacetylase;; Sulfotransferase domain	Heparan sulfate N-sulfotransferase 3 GN=NDST3 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 [Oryctolagus cuniculus]
ENSG00000164104(HMGB2)	--	39.708904	1203	38.62093521	1184	43.2751263	1359	50.1839394	1561	43.234562	1330	51.045742	1572	0.857673495	0.344614344	normal	0.973143953	0.146154402	normal	0.965285195	0.201555609	normal	0.194604233	0.23166222	normal	--	--	--	--	--	[R]	General function prediction only	HMG-box domain;; HMG (high mobility group) box	High mobility group protein B2 GN=HMGB2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: high mobility group protein B2 [Ovis aries]
ENSG00000164105(SAP30)	--	10.2443	183	11.08336	207	11.70302	218	16.3719	299	12.645903	227	14.125386	255	0.104281804	0.673008981	normal	0.960768028	0.11086138	normal	0.942790895	0.216487796	normal	0.242199964	0.339632763	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SAP30 zinc-finger;; Sin3 binding region of histone deacetylase complex subunit SAP30	Histone deacetylase complex subunit SAP30 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone deacetylase complex subunit SAP30 [Oryctolagus cuniculus]
ENSG00000164106(SCRG1)	--	0	0	0.013766	1	0	0	0	0	0.0131686	0	0.04048	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Scrapie-responsive protein 1	Scrapie-responsive protein 1 (Precursor) GN=SCRG1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: scrapie-responsive protein 1-like [Sus scrofa]
ENSG00000164107(HAND2)	--	1.04440337	49	0.602082262	29	0.974239	44	0.648234285	31	1.200263	47	0.979323	29	0.901060443	-0.664902716	normal	0.912424294	0.648398259	normal	0.939706542	-0.584813961	normal	0.800513651	-0.210065745	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K18486|2.68711e-109|rno:64637|Hand2; heart and neural crest derivatives expressed 2; K18486 heart-and neural crest derivatives-expressed protein 2 (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Heart- and neural crest derivatives-expressed protein 2 GN=HAND2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: heart- and neural crest derivatives-expressed protein 2 [Trichechus manatus latirostris]
ENSG00000164109(MAD2L1)	--	12.7503034	1003	12.53000787	985	14.2131425	1097	13.5972398	1080	11.499903	903	11.0199592	869	0.977822196	0.075765586	normal	0.968723241	-0.146589142	normal	0.845883239	-0.343892972	normal	0.542395782	-0.135013922	normal	--	--	--	K02537|3.64716e-148|ptr:461661|MAD2L1; MAD2 mitotic arrest deficient-like 1 (yeast); K02537 mitotic spindle assembly checkpoint protein MAD2 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	HORMA domain	Mitotic spindle assembly checkpoint protein MAD2A GN=MAD2L1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: mitotic spindle assembly checkpoint protein MAD2A [Galeopterus variegatus]
ENSG00000164111(ANXA5)	--	162.5422058	4815	170.6331981	5131	173.0936081	5128	206.605514	6160	173.3602791	5084	203.9589812	6036	0.947295931	0.324470561	normal	0.99315072	-0.034692281	normal	0.982445954	0.226843377	normal	0.375580777	0.175744955	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	K16646|0|ptr:461466|ANXA5; annexin A5; K16646 annexin A5 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A5 GN=ANXA5 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A5 [Lipotes vexillifer]
ENSG00000164112(TMEM155)	--	0.068281411	2	0.030373487	1	0	0	0.132512205	5	0.522400147	14	0.25997154	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein TMEM155 (Precursor) GN=TMEM155 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein TMEM155 [Ovis aries]
ENSG00000164114(MAP9)	--	8.246907132	788	8.099703001	830	7.956399795	833	7.622297448	828	7.066969308	789	9.057219	945	0.976393694	0.04052579	normal	0.972784787	-0.094336274	normal	0.96319402	0.173410637	normal	0.887347976	0.043118952	normal	--	--	--	"K10434|0|hsa:79884|MAP9, ASAP; microtubule-associated protein 9; K10434 microtubule-associated protein 9 (A)"	--	--	--	--	Microtubule-associated protein 9 GN=MAP9 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: microtubule-associated protein 9 [Ceratotherium simum simum]
ENSG00000164116(GUCY1A3)	--	0.040319739	2	0.020084576	1	0	0	0.12147849	7	0.158492208	11	0.123342988	9	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: guanylate cyclase activity (GO:0004383);; Biological Process: cGMP biosynthetic process (GO:0006182);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Molecular Function: heme binding (GO:0020037);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12318|0|hsa:2982|GUCY1A3, GC-SA3, GUC1A3, GUCA3, GUCSA3, GUCY1A1, MYMY6; guanylate cyclase 1, soluble, alpha 3 (EC:4.6.1.2); K12318 guanylate cyclase soluble subunit alpha [EC:4.6.1.2] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term depression (ko04730);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970)	[F]	Nucleotide transport and metabolism	Heme NO binding associated;; Adenylate and Guanylate cyclase catalytic domain;; Heme NO binding	Guanylate cyclase soluble subunit alpha-3 GN=GUCY1A3 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: guanylate cyclase soluble subunit alpha-3 isoform X1 [Galeopterus variegatus]
ENSG00000164117(FBXO8)	--	4.186543422	145	4.788419226	192	4.924155	184	6.073310024	196	6.40319	213	6.81052	241	0.845716905	0.400308524	normal	0.959205065	0.127367802	normal	0.845515381	0.378311303	normal	0.370688163	0.298696545	normal	--	--	Molecular Function: ARF guanyl-nucleotide exchange factor activity (GO:0005086);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of ARF protein signal transduction (GO:0032012);; 	K10294|0|ptr:461611|FBXO8; F-box protein 8; K10294 F-box protein 8 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec7 domain;; F-box-like	F-box only protein 8 GN=FBXO8 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: F-box only protein 8 [Oryctolagus cuniculus] 
ENSG00000164118(CEP44)	--	5.472201762	291	4.229512105	270	5.495232415	327	5.663308541	315	4.951688761	276	5.102527427	280	0.964785922	0.083078764	normal	0.966365639	0.010225655	normal	0.935877358	-0.230999525	normal	0.90591115	-0.049180727	normal	--	--	--	"K16761|0|hsa:80817|CEP44, KIAA1712, PS1TP3; centrosomal protein 44kDa; K16761 centrosomal protein CEP44 (A)"	--	--	--	"Centrosomal spindle body, CEP44"	Centrosomal protein of 44 kDa GN=CEP44 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 44 kDa [Galeopterus variegatus] 
ENSG00000164120(HPGD)	--	120.2106708	4370	90.4836833	3234	122.99805	4277	75.11047719	2813	87.47393185	3250	83.6966056	3087	0.013062505	-0.666061521	normal	0.990473085	-0.014299848	normal	0.517381922	-0.47848511	normal	0.057323636	-0.3973989	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K00069|0|ptr:461613|HPGD; hydroxyprostaglandin dehydrogenase 15-(NAD); K00069 15-hydroxyprostaglandin dehydrogenase (NAD) [EC:1.1.1.141] (A)	Transcriptional misregulation in cancer (ko05202)	[IR]	Lipid transport and metabolism;; General function prediction only	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; NAD dependent epimerase/dehydratase family	15-hydroxyprostaglandin dehydrogenase [NAD(+)] GN=HPGD OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 15-hydroxyprostaglandin dehydrogenase [NAD(+)] [Ursus maritimus]
ENSG00000164122(ASB5)	--	0	0	0	0	0.134427125	1	0	0	0.022510436	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10327|0|ptr:471357|ASB5; ankyrin repeat and SOCS box containing 5; K10327 ankyrin repeat and SOCS box protein 5 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 5 GN=ASB5 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 5 isoform X1 [Ochotona princeps]
ENSG00000164123(C4orf45)	--	0	0	0	0	0	0	0.0564348	1	0.0551754	0	0.0559997	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4562)	Uncharacterized protein C4orf45 GN=C4orf45 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C4orf45 homolog [Ceratotherium simum simum]
ENSG00000164124(TMEM144)	--	7.435604261	351	8.348990319	407	6.995050709	318	9.58478376	401	8.4247794	366	14.71395802	695	0.955641483	0.160640745	normal	0.952191247	-0.173929801	normal	1.75E-07	1.116014569	up	0.495969437	0.422400092	normal	--	--	Molecular Function: carbohydrate transmembrane transporter activity (GO:0015144);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: carbohydrate transmembrane transport (GO:0034219);; 	--	--	--	--	CEO family (DUF1632);; Sugar transport protein	Transmembrane protein 144 GN=TMEM144 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 144 [Orycteropus afer afer]
ENSG00000164125(FAM198B)	--	7.818458765	547	7.032408848	440	6.143821133	431	12.81637412	882	17.72763897	1255	17.12631662	1187	0.024548812	0.656939858	normal	9.33E-15	1.487522311	up	2.64E-14	1.45007212	up	3.02E-06	1.208629005	up	--	--	--	--	--	--	--	FAM198 protein	Protein FAM198B GN=FAM198B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM198B isoform 1 [Odobenus rosmarus divergens]
ENSG00000164128(NPY1R)	--	0.27564744	11	0.359250072	14	0.479476049	18	0.564641925	16	1.068265215	33	1.60869095	65	--	--	--	0.748731268	1.133786112	normal	0.000739881	1.761362074	up	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04204|0|hsa:4886|NPY1R, NPY1-R, NPYR; neuropeptide Y receptor Y1; K04204 neuropeptide Y receptor type 1 (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuropeptide Y receptor type 1 GN=NPY1R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuropeptide Y receptor type 1 [Chrysochloris asiatica]
ENSG00000164129(NPY5R)	--	0.0541795	1	0	0	0	0	0.0819391	2	0.086108	1	0.082109	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04207|0|ptr:461582|NPY5R; neuropeptide Y receptor Y5; K04207 neuropeptide Y receptor type 5 (A)	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuropeptide Y receptor type 5 GN=NPY5R OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: neuropeptide Y receptor Y5 [Pteropus alecto]
ENSG00000164134(NAA15)	--	19.67087001	2061	20.99153644	2192	22.2723582	2262	21.94906182	2315	22.78880825	2364	17.50739592	1818	0.982180502	0.13673921	normal	0.985757786	0.087497544	normal	0.90543853	-0.323296571	normal	0.931501826	-0.025710022	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K00670|0|hsa:80155|NAA15, Ga19, NARG1, NAT1P, NATH, TBDN, TBDN100; N(alpha)-acetyltransferase 15, NatA auxiliary subunit; K00670 peptide alpha-N-acetyltransferase [EC:2.3.1.88] (A)"	--	[B]	Chromatin structure and dynamics	NMDA receptor-regulated protein 1;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	"N-alpha-acetyltransferase 15, NatA auxiliary subunit GN=NAA15 OS=Homo sapiens (Human) PE=1 SV=1"	B	Chromatin structure and dynamics	"PREDICTED: N-alpha-acetyltransferase 15, NatA auxiliary subunit isoform X1 [Equus caballus] "
ENSG00000164136(IL15)	--	5.1400417	203	5.049197908	204	5.88421733	220	5.595781202	187	7.710479611	262	6.062945039	240	0.958117808	-0.148105313	normal	0.878626254	0.337359336	normal	0.961337255	0.116472683	normal	0.779113098	0.115804255	normal	--	--	Molecular Function: cytokine receptor binding (GO:0005126);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; 	K05433|4.14196e-98|ptr:737808|IL15; interleukin 15; K05433 interleukin 15 (A)	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; TNF signaling pathway (ko04668);; Intestinal immune network for IgA production (ko04672);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Rheumatoid arthritis (ko05323)	--	--	Interleukin 15	Interleukin-15 (Precursor) GN=IL15 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-15 [Galeopterus variegatus]
ENSG00000164142(FAM160A1)	--	0.502689743	63	0.890419026	69	0.937381943	72	1.195224393	179	1.594133506	154	2.521173759	208	1.62E-06	1.453769575	up	0.001767604	1.11998936	up	1.06E-07	1.502801293	up	3.35E-06	1.38639657	up	--	--	--	--	--	[S]	Function unknown	Retinoic acid induced 16-like protein	Protein FAM160A1 GN=FAM160A1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM160A1 [Ceratotherium simum simum]
ENSG00000164144(ARFIP1)	--	12.20887781	582	13.6477385	660	12.06252543	569	13.57590169	692	15.13934305	731	13.97352062	662	0.944259067	0.218391399	normal	0.967335745	0.125705056	normal	0.94727553	0.20959422	normal	0.42207014	0.181801777	normal	--	--	Molecular Function: protein domain specific binding (GO:0019904);; 	--	--	[T]	Signal transduction mechanisms	Arfaptin-like domain	Arfaptin-1 GN=ARFIP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: arfaptin-1 isoform X1 [Ursus maritimus] 
ENSG00000164151(ICE1)	--	12.321651	2027	14.3709826	2348	14.824882	2410	13.1032038	2161	14.1459951	2344	12.2637854	2031	0.986308395	0.061475588	normal	0.987834432	-0.023871009	normal	0.956686842	-0.254959845	normal	0.751610688	-0.075104797	normal	--	--	--	--	--	--	--	--	Little elongation complex subunit 1 GN=ICE1 OS=Homo sapiens (Human) PE=1 SV=5	S	Function unknown	PREDICTED: uncharacterized protein KIAA0947 homolog [Galeopterus variegatus]
ENSG00000164161(HHIP)	--	0.48291565	38	0.47606101	37	0.527091406	32	0.925266463	51	1.452762279	81	1.2644686	67	0.963917451	0.380352829	normal	0.09440833	1.078480626	normal	0.279804686	1.023659722	normal	0.070464581	0.874604803	normal	--	--	--	"K06231|0|hsa:64399|HHIP, HIP; hedgehog interacting protein; K06231 hedgehog interacting protein (A)"	cAMP signaling pathway (ko04024);; Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	--	--	Folate receptor family;; Glucose / Sorbosone dehydrogenase	Hedgehog-interacting protein (Precursor) GN=HHIP OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: hedgehog-interacting protein-like [Odobenus rosmarus divergens]
ENSG00000164162(ANAPC10)	--	6.6061204	100	9.886301	149	10.482957	138	9.445766	148	7.782285	118	9.074728	138	0.729565413	0.52805874	normal	0.903654322	-0.353905667	normal	0.96827594	-0.008201565	normal	0.954684329	0.040625397	normal	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	--	K03357|3.92581e-138|mcf:101867410|uncharacterized LOC101867410; K03357 anaphase-promoting complex subunit 10 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"Anaphase-promoting complex, subunit 10 (APC10)"	Anaphase-promoting complex subunit 10 GN=ANAPC10 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anaphase-promoting complex subunit 10 isoform X1 [Myotis brandtii] 
ENSG00000164163(ABCE1)	--	42.38512657	2363	41.7891455	2341	44.35279523	2438	44.68058653	2587	41.2784208	2387	35.53585481	2029	0.986254499	0.099766154	normal	0.988021606	0.006642825	normal	0.948236255	-0.273034777	normal	0.848304942	-0.050186753	normal	[R]	General function prediction only	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K06174|0|ptr:461523|ABCE1; ATP-binding cassette, sub-family E (OABP), member 1; K06174 ATP-binding cassette, sub-family E, member 1 (A)"	--	[A]	RNA processing and modification	"ABC transporter;; Possible Fer4-like domain in RNase L inhibitor, RLI;; AAA domain;; RecF/RecN/SMC N terminal domain;; AAA ATPase domain;; 4Fe-4S binding domain;; AAA ATPase domain;; AAA domain;; ATPase family associated with various cellular activities (AAA);; Protein of unknown function, DUF258;; Miro-like protein;; NACHT domain"	ATP-binding cassette sub-family E member 1 GN=OK/SW-cl.40 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ATP-binding cassette sub-family E member 1 [Eptesicus fuscus]
ENSG00000164164(OTUD4)	--	11.00180763	1379	10.34077995	1302	10.80629968	1367	12.41249252	1638	11.72956195	1531	11.65872636	1482	0.961260963	0.217258331	normal	0.961585537	0.212090901	normal	0.979470481	0.108125853	normal	0.35099152	0.178877403	normal	--	--	--	K13718|0|pon:100431477|OTUD4; OTU deubiquitinase 4; K13718 OTU domain-containing protein 4 [EC:3.4.19.12] (A)	--	--	--	OTU-like cysteine protease;; Peptidase C65 Otubain	OTU domain-containing protein 4 GN=OTUD4 OS=Homo sapiens (Human) PE=1 SV=4	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: OTU domain-containing protein 4 [Oryctolagus cuniculus]
ENSG00000164167(LSM6)	--	3.340454	95	6.250052001	188	5.742458977	176	6.896375	215	4.845017334	142	6.787761353	205	0.000144832	1.134986462	up	0.822136576	-0.422345299	normal	0.947145284	0.210082967	normal	0.632235429	0.270823589	normal	[K]	Transcription	--	"K12625|1.961e-52|pon:100436232|LSM6; LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae); K12625 U6 snRNA-associated Sm-like protein LSm6 (A)"	RNA degradation (ko03018);; Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm6 GN=LSM6 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U6 snRNA-associated Sm-like protein LSm6 isoform X1 [Galeopterus variegatus]
ENSG00000164168(TMEM184C)	--	12.97205858	887	14.3167	1056	13.62416313	882	13.67245805	944	13.4942156	959	16.78027108	1111	0.977151928	0.058921555	normal	0.9674512	-0.160192821	normal	0.875016156	0.324220455	normal	0.7814043	0.072510126	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Organic solute transporter Ostalpha	Transmembrane protein 184C GN=TMEM184C OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: transmembrane protein 184C [Lipotes vexillifer]
ENSG00000164169(PRMT9)	--	1.93667	116	1.86173	112	1.50234	89	2.39331	145	1.74787	104	1.55746	93	0.935645644	0.287682164	normal	0.964655327	-0.126567737	normal	0.97118042	0.054232407	normal	0.887815592	0.086453537	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	--	--	Ribosomal protein L11 methyltransferase (PrmA);; Tetratricopeptide repeat;; TPR repeat;; Methyltransferase domain;; Tetratricopeptide repeat;; Methyltransferase small domain	Putative protein arginine N-methyltransferase 9 GN=PRMT9 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: putative protein arginine N-methyltransferase 10 isoform 1 [Ceratotherium simum simum]
ENSG00000164171(ITGA2)	--	32.7436	4641	23.292	3276	27.5988	3824	26.572	3771	20.0663	2839	23.7978	3381	0.932123679	-0.330199278	normal	0.972746405	-0.227865956	normal	0.982811807	-0.185845732	normal	0.395358978	-0.254495204	normal	--	--	--	"K06481|0|hsa:3673|ITGA2, BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2; integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); K06481 integrin alpha 2 (A)"	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Hematopoietic cell lineage (ko04640);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Small cell lung cancer (ko05222);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[W]	Extracellular structures	"Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; von Willebrand factor type A domain;; FG-GAP repeat;; Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella"	Integrin alpha-2 (Precursor) GN=ITGA2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: integrin alpha-2 [Galeopterus variegatus]
ENSG00000164172(MOCS2)	--	29.08041656	655	27.12079185	604	28.31646651	624	30.95231535	709	28.59385711	654	28.83151768	652	0.972026366	0.083270694	normal	0.969657637	0.093091501	normal	0.973137719	0.054904312	normal	0.788665466	0.076284676	normal	[H]	Coenzyme transport and metabolism	Biological Process: Mo-molybdopterin cofactor biosynthetic process (GO:0006777);; 	"K03635|2.15595e-106|hsa:4338|MOCS2, MCBPE, MOCO1, MOCODB, MPTS; molybdenum cofactor synthesis 2 (EC:2.8.1.12); K03635 molybdopterin synthase catalytic subunit [EC:2.8.1.12] (A)"	Folate biosynthesis (ko00790);; Sulfur relay system (ko04122)	[H]	Coenzyme transport and metabolism	MoaE protein	Molybdopterin synthase catalytic subunit {ECO:0000255|HAMAP-Rule:MF_03052} OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: molybdenum cofactor synthesis 2 [Orcinus orca]
ENSG00000164175(SLC45A2)	--	0	0	0	0	0	0	0	0	0	0	0.110429027	1	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K15378|0|nle:100584203|SLC45A2; solute carrier family 45, member 2; K15378 solute carrier family 45, member 1/2/4 (A)"	--	[G]	Carbohydrate transport and metabolism	MFS/sugar transport protein;; Major Facilitator Superfamily	Membrane-associated transporter protein GN=SLC45A2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: membrane-associated transporter protein isoform 2 [Ceratotherium simum simum]
ENSG00000164176(EDIL3)	--	9.939616726	625	8.38701829	520	12.55642179	769	16.479033	1063	20.2700803	1277	19.757946	1260	0.003359646	0.733982763	normal	7.41E-11	1.272310052	up	0.006133094	0.702986053	normal	8.71E-07	0.891356773	normal	--	--	--	--	--	--	--	F5/8 type C domain;; EGF-like domain;; EGF-like domain	EGF-like repeat and discoidin I-like domain-containing protein 3 (Precursor) GN=EDIL3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: EGF-like repeat and discoidin I-like domain-containing protein 3-like [Tupaia chinensis]
ENSG00000164180(TMEM161B)	--	10.4986601	363	12.20651495	408	10.76446432	356	8.920166301	306	8.719399444	285	9.4123184	330	0.912777708	-0.275995914	normal	0.356531679	-0.536640174	normal	0.962141845	-0.117185476	normal	0.209372689	-0.31237933	normal	--	--	--	--	--	[S]	Function unknown	Predicted transmembrane protein 161AB	Transmembrane protein 161B GN=TMEM161B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein PANDA_001482 [Ailuropoda melanoleuca]
ENSG00000164181(ELOVL7)	--	9.449317829	495	13.64040801	625	9.652052694	438	15.73280063	724	12.91737741	537	19.35663691	858	0.307919833	0.516396525	normal	0.933730753	-0.239734153	normal	9.96E-06	0.95934488	normal	0.267723815	0.422431555	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K10250|0|hsa:79993|ELOVL7; ELOVL fatty acid elongase 7 (EC:2.3.1.199); K10250 elongation of very long chain fatty acids protein 7 [EC:2.3.1.199] (A)	Fatty acid elongation (ko00062)	[I]	Lipid transport and metabolism	GNS1/SUR4 family	Elongation of very long chain fatty acids protein 7 GN=ELOVL7 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: elongation of very long chain fatty acids protein 7 [Myotis davidii]
ENSG00000164182(NDUFAF2)	--	46.49888	491	47.373387	484	48.092363	531	56.207724	617	54.60563381	564	39.56745324	428	0.893487952	0.297882221	normal	0.948279869	0.198686023	normal	0.873463414	-0.318380482	normal	0.817737445	0.07337739	normal	--	--	Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; Molecular Function: electron carrier activity (GO:0009055);; Cellular Component: membrane (GO:0016020);; 	"K18160|4.62915e-106|ptr:461857|NDUFAF2, NDUFA12L; NADH dehydrogenase (ubiquinone) complex I, assembly factor 2; K18160 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 (A)"	--	--	--	NADH ubiquinone oxidoreductase subunit NDUFA12	"Mimitin, mitochondrial (Precursor) GN=NDUFAF2 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: mimitin, mitochondrial [Ceratotherium simum simum]"
ENSG00000164185(ZNF474)	--	0.106942206	4	0.0272403	1	0.309371112	2	0.0268182	1	0.103499591	3	0.185213	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"zinc-finger of a C2HC-type;; Zinc finger, C2H2 type"	Zinc finger protein 474 GN=ZNF474 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 474-like [Ceratotherium simum simum]
ENSG00000164187(LMBRD2)	--	4.401765	491	4.216493295	467	4.631305309	502	4.729879355	534	4.030895446	451	5.541776623	620	0.968202609	0.090014324	normal	0.967849102	-0.071486092	normal	0.896197861	0.295487025	normal	0.680962758	0.115889196	normal	--	--	--	--	--	[R]	General function prediction only	LMBR1-like membrane protein	LMBR1 domain-containing protein 2 GN=LMBRD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LMBR1 domain-containing protein 2 [Pteropus alecto]
ENSG00000164190(NIPBL)	--	8.136227	1617	10.218101	1956	9.033584	1849	7.263447	1444	7.571716	1457	7.5496	1573	0.967918904	-0.193886109	normal	0.602383398	-0.445930996	normal	0.955748561	-0.241303771	normal	0.068931006	-0.298174812	normal	--	--	--	K06672|0|pps:100976618|NIPBL; Nipped-B homolog (Drosophila); K06672 cohesin loading factor subunit SCC2 (A)	--	[BDL]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Sister chromatid cohesion C-terminus;; HEAT repeat associated with sister chromatid cohesion;; HEAT repeats;; HEAT-like repeat	Nipped-B-like protein GN=NIPBL OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nipped-B-like protein isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000164197(RNF180)	--	0.0351681	2	0.180158887	7	0.10926799	7	0.308282803	11	0.19634612	10	0.14693322	6	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: metal ion binding (GO:0046872);; 	"K15708|0|hsa:285671|RNF180, RINES; ring finger protein 180; K15708 E3 ubiquitin-protein ligase RNF180 [EC:6.3.2.19] (A)"	--	[V]	Defense mechanisms	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF180 GN=RNF180 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF180-like isoform X3 [Tupaia chinensis]
ENSG00000164199(ADGRV1)	--	0.0420981	1	0.1912017	7	0.09322962	1	2.149471295	51	2.3761398	53	1.34177	32	7.56E-10	4.35140679	up	5.35E-06	2.659737453	up	2.42E-05	3.73200943	up	4.11E-10	3.892990745	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: cell communication (GO:0007154);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K18263|0|hsa:84059|GPR98, FEB4, MASS1, USH2B, USH2C, VLGR1, VLGR1b, ADGRV1; G protein-coupled receptor 98; K18263 G-protein coupled receptor 98 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Calx-beta domain;; EPTP domain;; Concanavalin A-like lectin/glucanases superfamily;; 7 transmembrane receptor (Secretin family);; Latrophilin/CL-1-like GPS domain	G-protein coupled receptor 98 (Precursor) GN=GPR98 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 98 [Equus caballus]
ENSG00000164209(SLC25A46)	--	26.78017937	885	29.871431	924	31.89017289	968	33.49742031	1086	31.14001017	1022	28.8580891	953	0.929815458	0.264028125	normal	0.972277708	0.123811149	normal	0.97879795	-0.03077382	normal	0.60106109	0.119008105	normal	--	--	--	"K03454|0|ptr:461986|SLC25A46; solute carrier family 25, member 46; K03454 solute carrier family 25, member 46 (A)"	--	[R]	General function prediction only	Mitochondrial carrier protein	Solute carrier family 25 member 46 GN=SLC25A46 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 46 [Galeopterus variegatus]
ENSG00000164211(STARD4)	--	22.79067857	1125	24.74021802	1285	23.460984	1206	10.7974833	575	11.980308	647	23.85333669	1207	1.29E-06	-0.997180387	normal	9.97E-07	-1.009648401	down	0.981723912	-0.00708679	normal	0.150883387	-0.593009801	normal	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[I]	Lipid transport and metabolism	START domain	StAR-related lipid transfer protein 4 GN=STARD4 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: stAR-related lipid transfer protein 4-like [Tupaia chinensis]
ENSG00000164219(PGGT1B)	--	9.666463	500	9.084321	445	9.1665163	381	10.291661	588	10.04366	569	9.412258	459	0.947900222	0.202481587	normal	0.858047788	0.332196204	normal	0.921464838	0.25947212	normal	0.238320253	0.263127675	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: catalytic activity (GO:0003824);; 	"K11713|0|pps:100989189|PGGT1B; protein geranylgeranyltransferase type I, beta subunit; K11713 geranylgeranyl transferase type-1 subunit beta [EC:2.5.1.59] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prenyltransferase and squalene oxidase repeat;; Prenyltransferase-like	Geranylgeranyl transferase type-1 subunit beta GN=PGGT1B OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: geranylgeranyl transferase type-1 subunit beta isoform 1 [Equus caballus] 
ENSG00000164220(F2RL2)	--	3.956690094	185	5.11883	234	4.26955	194	2.003361606	93	1.45779	68	1.1896	56	0.002693525	-1.010969505	down	4.26E-11	-1.781587079	down	7.12E-10	-1.773467502	down	6.28E-08	-1.521171259	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04235|0|ptr:100614246|F2RL2; coagulation factor II (thrombin) receptor-like 2; K04235 coagulation factor II (thrombin) receptor-like 2 (A)	Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family)	Proteinase-activated receptor 3 (Precursor) GN=F2RL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: proteinase-activated receptor 3 isoform X2 [Panthera tigris altaica]
ENSG00000164221(CCDC112)	--	4.396513178	227	4.425946085	228	4.727298095	242	4.701143711	249	4.2759644	223	3.961904705	208	0.96269295	0.101962131	normal	0.964760032	-0.053060794	normal	0.940801219	-0.225195485	normal	0.901973769	-0.057262565	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 112 GN=CCDC112 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 112 [Galeopterus variegatus]
ENSG00000164236(ANKRD33B)	--	4.373662	762	4.474028235	785	6.067503782	1049	4.013947918	690	2.446094331	420	3.24806929	557	0.959834729	-0.173658721	normal	5.05E-05	-0.921262136	normal	1.91E-05	-0.919706358	normal	0.033454681	-0.660570457	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Ankyrin repeat domain-containing protein 33B GN=ANKRD33B OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 33B-like [Bubalus bubalis]
ENSG00000164237(CMBL)	--	16.3065	660	16.8259	683	19.1769	772	14.2839	585	13.111	529	14.8255	603	0.949001194	-0.204355952	normal	0.756189621	-0.389062622	normal	0.803411088	-0.36392551	normal	0.095918994	-0.321664332	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: hydrolase activity (GO:0016787);; 	"K01061|0|hsa:134147|CMBL, JS-1; carboxymethylenebutenolidase homolog (Pseudomonas) (EC:3.1.-.-); K01061 carboxymethylenebutenolidase [EC:3.1.1.45] (A)"	--	[R]	General function prediction only	Dienelactone hydrolase family;; Alpha/beta hydrolase family;; Prolyl oligopeptidase family;; Alpha/beta hydrolase family;; Phospholipase/Carboxylesterase;; BAAT / Acyl-CoA thioester hydrolase C terminal	Carboxymethylenebutenolidase homolog GN=CMBL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carboxymethylenebutenolidase homolog [Tupaia chinensis]
ENSG00000164241(C5orf63)	--	7.801638413	139	5.396742499	105	7.800128204	118	5.6445365	109	13.08428108	117	18.26496599	129	0.898700178	-0.376871546	normal	0.963860369	0.132879028	normal	0.965036755	0.118835739	normal	0.943924155	-0.048847501	normal	--	--	--	--	--	--	--	Glutaredoxin-like domain (DUF836)	Glutaredoxin-like protein C5orf63 GN=C5orf63 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: glutaredoxin-like protein C5orf63 homolog isoform X5 [Tupaia chinensis]
ENSG00000164244(PRRC1)	--	24.538122	1635	22.750762	1494	22.79019484	1475	25.02932672	1674	28.8908681	1904	25.38789281	1714	0.985045822	0.003173681	normal	0.894502452	0.328131924	normal	0.965166555	0.208162555	normal	0.344467776	0.179784108	normal	--	--	--	--	--	--	--	Protein of unknown function DUF84	Protein PRRC1 GN=PRRC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein PRRC1 isoform X1 [Tupaia chinensis] 
ENSG00000164251(F2RL1)	--	63.726985	3028	49.34858003	2396	53.55541841	2551	50.29642359	2295	60.62835641	2837	37.03996671	1769	0.685518271	-0.430451509	normal	0.971178481	0.222182685	normal	0.208710827	-0.536036494	normal	0.511298928	-0.230446751	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04234|0|hsa:2150|F2RL1, GPR11, PAR2; coagulation factor II (thrombin) receptor-like 1; K04234 coagulation factor II (thrombin) receptor-like 1 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Inflammatory mediator regulation of TRP channels (ko04750);; African trypanosomiasis (ko05143)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srw	"Proteinase-activated receptor 2, alternate cleaved 2 (Precursor) GN=F2RL1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	PREDICTED: proteinase-activated receptor 2 [Galeopterus variegatus]
ENSG00000164252(AGGF1)	--	13.000688	1098	15.269417	1288	13.96931826	1161	15.729972	1339	14.339672	1212	14.74193103	1249	0.940437232	0.255121957	normal	0.977285887	-0.109037447	normal	0.978255428	0.096992233	normal	0.748327185	0.077884013	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	FHA domain;; G-patch domain;; DExH-box splicing factor binding site	Angiogenic factor with G patch and FHA domains 1 GN=AGGF1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: angiogenic factor with G patch and FHA domains 1-like [Ceratotherium simum simum]
ENSG00000164253(WDR41)	--	17.6924923	916	16.55915808	824	17.8891675	841	19.681428	959	17.507678	809	18.07897958	911	0.978319301	0.035293098	normal	0.975752924	-0.047842575	normal	0.973221082	0.106869128	normal	0.913514069	0.03230751	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 41 GN=WDR41 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: WD repeat-containing protein 41 isoform X1 [Galeopterus variegatus]
ENSG00000164256(PRDM9)	--	0	0	0	0	0	0	0	0	0.14313545	2	0.0109655	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; SSXRD motif;; KRAB box;; Probable zinc-binding domain;; SET domain"	Histone-lysine N-methyltransferase PRDM9 GN=PRDM9 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	"PREDICTED: histone-lysine N-methyltransferase PRDM9-like, partial [Tursiops truncatus]"
ENSG00000164258(NDUFS4)	--	58.10056	497	52.88921	456	49.25824	423	67.29707	598	62.83899	532	55.83686	478	0.935102357	0.235403217	normal	0.947124467	0.200350228	normal	0.955655526	0.167497873	normal	0.398774836	0.202722588	normal	--	--	"Molecular Function: oxidoreductase activity, acting on NAD(P)H (GO:0016651);; Biological Process: electron transport chain (GO:0022900);; "	"K03937|6.38748e-112|hsa:4724|NDUFS4, AQDQ, CI-18; NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase); K03937 NADH dehydrogenase (ubiquinone) Fe-S protein 4 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	ETC complex I subunit conserved region	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (Precursor) GN=NDUFS4 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial [Pteropus alecto] "
ENSG00000164266(SPINK1)	--	0	0	0	0	0	0	0.956041	5	0.391686	1	2.53221	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Pancreatic secretory trypsin inhibitor (Precursor) GN=SPINK1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: pancreatic secretory trypsin inhibitor [Equus caballus] 
ENSG00000164283(ESM1)	--	0	0	0	0	0	0	0.027438656	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; 	--	--	[T]	Signal transduction mechanisms	Insulin-like growth factor binding protein	Endothelial cell-specific molecule 1 (Precursor) GN=ESM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: endothelial cell-specific molecule 1 isoform X1 [Orycteropus afer afer]
ENSG00000164284(GRPEL2)	--	7.149533125	410	6.956799106	399	7.041213747	397	5.949473	345	7.323150432	415	7.384405764	424	0.909653129	-0.278719449	normal	0.968505636	0.035165343	normal	0.966562175	0.086315609	normal	0.898477272	-0.047123103	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: adenyl-nucleotide exchange factor activity (GO:0000774);; Biological Process: protein folding (GO:0006457);; Molecular Function: protein homodimerization activity (GO:0042803);; Molecular Function: chaperone binding (GO:0051087);; 	"K03687|5.33743e-162|hsa:134266|GRPEL2, Mt-GrpE#2; GrpE-like 2, mitochondrial (E. coli); K03687 molecular chaperone GrpE (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	GrpE	"GrpE protein homolog 2, mitochondrial (Precursor) GN=GRPEL2 OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: grpE protein homolog 2, mitochondrial [Equus caballus] "
ENSG00000164287(CDC20B)	--	0.020942871	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"WD domain, G-beta repeat"	Cell division cycle protein 20 homolog B GN=CDC20B OS=Homo sapiens (Human) PE=2 SV=3	DO	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: cell division cycle protein 20 homolog B isoform X1 [Panthera tigris altaica]
ENSG00000164291(ARSK)	--	4.48454	186	4.20415	192	3.785122	168	5.16531	206	4.095003	183	4.168512	203	0.961834413	0.115601856	normal	0.962843595	-0.08996331	normal	0.9321626	0.262573869	normal	0.835102099	0.095197577	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K12376|0|hsa:153642|ARSK, TSULF; arylsulfatase family, member K; K12376 arylsulfatase K [EC:3.1.6.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Sulfatase	Arylsulfatase K (Precursor) GN=ARSK OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: arylsulfatase K [Galeopterus variegatus]
ENSG00000164292(RHOBTB3)	--	12.81615991	999	12.2109887	992	13.21092417	1041	14.910123	1240	15.85060838	1332	16.278335	1326	0.921832763	0.280563371	normal	0.727511933	0.403223301	normal	0.858145683	0.340380121	normal	0.037691801	0.341582783	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: protein binding (GO:0005515);; Molecular Function: GTP binding (GO:0005525);; 	K07869|0|hsa:22836|RHOBTB3; Rho-related BTB domain containing 3; K07869 Rho-related BTB domain-containing protein 3 (A)	--	--	--	BTB/POZ domain;; Ras family	Rho-related BTB domain-containing protein 3 GN=RHOBTB3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rho-related BTB domain-containing protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000164294(GPX8)	--	45.36817	1402	43.0008	1389	48.91831	1576	40.50427	1325	38.81842	1188	52.71651	1669	0.978512901	-0.112199744	normal	0.946693817	-0.246647605	normal	0.983185374	0.074355637	normal	0.792180681	-0.082766685	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: glutathione peroxidase activity (GO:0004602);; Biological Process: response to oxidative stress (GO:0006979);; Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00432|6.93138e-141|hsa:493869|GPX8, EPLA847, GPx-8, GSHPx-8, UNQ847; glutathione peroxidase 8 (putative) (EC:1.11.1.9); K00432 glutathione peroxidase [EC:1.11.1.9] (A)"	Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590);; Thyroid hormone synthesis (ko04918)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glutathione peroxidase;; AhpC/TSA family	Probable glutathione peroxidase 8 GN=GPX8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable glutathione peroxidase 8 [Galeopterus variegatus]
ENSG00000164296(TIGD6)	--	2.90857	160	2.58132	155	1.68929989	98	1.606462	92	2.182226	117	2.202237	123	0.080376845	-0.818691392	normal	0.850073561	-0.42242561	normal	0.933938818	0.31516345	normal	0.425120431	-0.336010399	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; Tc5 transposase DNA-binding domain;; CENP-B N-terminal DNA-binding domain	Tigger transposable element-derived protein 6 GN=TIGD6 OS=Homo sapiens (Human) PE=2 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: tigger transposable element-derived protein 6 [Galeopterus variegatus]
ENSG00000164300(SERINC5)	--	16.963003	1683	17.00801	1648	15.0559717	1519	11.50981244	1176	12.15604554	1231	20.18260437	2056	0.161950324	-0.547378005	normal	0.606631983	-0.441841085	normal	0.657499758	0.428059299	normal	0.795856834	-0.13963547	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Serine incorporator (Serinc)	Serine incorporator 5 GN=SERINC5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: serine incorporator 5 [Balaenoptera acutorostrata scammoni]
ENSG00000164304(CAGE1)	--	0.01811543	1	0	0	0.0293532	0	0.0579656	2	0	0	0.029102	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cancer-associated gene protein 1 family	Cancer-associated gene 1 protein GN=CAGE1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: cancer-associated gene 1 protein homolog [Pteropus alecto]
ENSG00000164305(CASP3)	--	9.712720023	389	9.719847459	369	8.530739087	328	12.34260472	505	13.12963093	531	10.6257186	434	0.841509041	0.344484003	normal	0.424266713	0.501941017	normal	0.764597646	0.394123138	normal	0.04726856	0.414986648	normal	--	--	--	"K02187|0|pps:100974934|CASP3; caspase 3, apoptosis-related cysteine peptidase; K02187 caspase 3 [EC:3.4.22.56] (A)"	MAPK signaling pathway (ko04010);; p53 signaling pathway (ko04115);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; TNF signaling pathway (ko04668);; Serotonergic synapse (ko04726);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Pertussis (ko05133);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Viral myocarditis (ko05416)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain	Caspase-3 subunit p12 (Precursor) GN=CASP3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-3 isoform X2 [Ursus maritimus]
ENSG00000164306(PRIMPOL)	--	4.311897	162	4.488888024	174	4.663289696	173	4.062274565	155	3.717507875	141	4.010856167	151	0.964714413	-0.093649703	normal	0.910716042	-0.321706284	normal	0.951171872	-0.202617546	normal	0.61339268	-0.208659615	normal	--	--	--	--	--	--	--	Herpesviridae UL52/UL70 DNA primase;; Eukaryotic and archaeal DNA primase small subunit	DNA-directed primase/polymerase protein GN=PRIMPOL OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 111 [Trichechus manatus latirostris]
ENSG00000164307(ERAP1)	--	8.764264	724	9.02525	649	9.954815	646	11.800339	853	12.00691	852	10.699788	793	0.952330801	0.205322027	normal	0.796231581	0.370452943	normal	0.906608517	0.286888092	normal	0.132256011	0.28566084	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	K09604|0|ptr:471835|ERAP1; endoplasmic reticulum aminopeptidase 1; K09604 adipocyte-derived leucine aminopeptidase [EC:3.4.11.-] (A)	--	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	Endoplasmic reticulum aminopeptidase 1 GN=ERAP1 OS=Homo sapiens (Human) PE=1 SV=3	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: endoplasmic reticulum aminopeptidase 1 [Galeopterus variegatus]
ENSG00000164308(ERAP2)	--	1.019119737	81	0.901839686	82	0.794176751	59	1.910585681	156	2.086831987	156	1.897671891	170	0.034444538	0.902187209	normal	0.039022884	0.894274276	normal	1.16E-06	1.494860616	up	0.000455128	1.096986574	up	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	"K13723|0|hsa:64167|ERAP2, L-RAP, LRAP; endoplasmic reticulum aminopeptidase 2 (EC:3.4.11.-); K13723 endoplasmic reticulum aminopeptidase 2 [EC:3.4.11.-] (A)"	--	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	Endoplasmic reticulum aminopeptidase 2 GN=ERAP2 OS=Homo sapiens (Human) PE=1 SV=2	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: endoplasmic reticulum aminopeptidase 2 isoform X1 [Galeopterus variegatus]
ENSG00000164309(CMYA5)	--	0.0158534	5	0.0160399	5	0.0318773	9	0.0222741	7	0.0122981	3	0.0189228	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Fibronectin type III domain;; SPRY domain	Cardiomyopathy-associated protein 5 GN=CMYA5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cardiomyopathy-associated protein 5 [Myotis lucifugus]
ENSG00000164318(EGFLAM)	--	0.044576657	2	0	0	0	0	0.016579916	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Laminin G domain;; Laminin G domain;; Fibronectin type III domain;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain	Pikachurin (Precursor) GN=EGFLAM OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: pikachurin isoform X1 [Equus przewalskii]
ENSG00000164323(CFAP97)	--	12.040397	885	11.107081	806	12.20658	883	11.1145611	836	11.4820864	853	9.51221	707	0.972269686	-0.112805234	normal	0.975388675	0.060229489	normal	0.863728671	-0.328364816	normal	0.595231857	-0.124913975	normal	--	--	--	--	--	--	--	KIAA1430 homologue	Cilia- and flagella-associated protein 97 {ECO:0000312|HGNC:HGNC:29276} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0501 protein KIAA1430 homolog [Physeter catodon]
ENSG00000164327(RICTOR)	--	6.906891353	1040	9.657763095	1436	7.789104154	1092	6.749662598	998	6.602704258	985	9.965989025	1334	0.976578358	-0.09016807	normal	0.136873851	-0.564564226	normal	0.924825007	0.280142804	normal	0.765057036	-0.125863897	normal	--	--	--	"K08267|0|hsa:253260|RICTOR, AVO3, PIA, hAVO3; RPTOR independent companion of MTOR, complex 2; K08267 rapamycin-insensitive companion of mTOR (A)"	mTOR signaling pathway (ko04150)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Rapamycin-insensitive companion of mTOR, N-term;; Rapamycin-insensitive companion of mTOR, middle domain;; Rapamycin-insensitive companion of mTOR, phosphorylation-site;; Rapamycin-insensitive companion of mTOR RasGEF_N domain;; Rapamycin-insensitive companion of mTOR, domain 5"	Rapamycin-insensitive companion of mTOR OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: rapamycin-insensitive companion of mTOR isoform X1 [Mustela putorius furo]
ENSG00000164329(PAPD4)	--	13.76050625	726	15.94714287	827	14.978535	760	16.03225565	849	16.16346529	853	14.74072757	784	0.955630697	0.194581667	normal	0.976796808	0.0231901	normal	0.976076189	0.0364913	normal	0.752471857	0.082592901	normal	[L]	"Replication, recombination and repair"	--	"K14079|0|hsa:167153|PAPD4, GLD2, TUT2; PAP associated domain containing 4 (EC:2.7.7.19); K14079 poly(A) RNA polymerase GLD2 [EC:2.7.7.19] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cid1 family poly A polymerase	Poly(A) RNA polymerase GLD2 GN=PAPD4 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: poly(A) RNA polymerase GLD2 isoformX2 [Canis lupus familiaris] 
ENSG00000164330(EBF1)	--	0.401867379	33	0.364376838	29	0.402312095	34	0.50081803	35	0.55201815	48	0.749267236	58	0.983640868	0.051718444	normal	0.897665567	0.67782791	normal	0.813680814	0.736859719	normal	0.391342023	0.535108659	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09103|0|nle:100604994|EBF1; early B-cell factor 1; K09103 early B-cell factor (A)	--	[K]	Transcription	IPT/TIG domain	Transcription factor COE1 GN=EBF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor COE1 isoform 1 [Trichechus manatus latirostris] 
ENSG00000164331(ANKRA2)	--	5.67602	195	5.42297	188	5.550690014	190	7.526643	251	5.781781	199	9.60858	333	0.887236559	0.331076729	normal	0.964499324	0.060138987	normal	0.01022248	0.79638228	normal	0.246159917	0.430068658	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat family A protein 2 GN=ANKRA2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat family A protein 2 isoform X1 [Tupaia chinensis]
ENSG00000164332(UBLCP1)	--	28.8566	1104	25.9509	975	28.1118	1043	30.5942	1171	28.7004	1095	26.7813	1028	0.979972979	0.054095539	normal	0.970230734	0.145816684	normal	0.979708664	-0.029147765	normal	0.834231328	0.055817448	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17618|0|umr:103664532|UBLCP1; ubiquitin-like domain containing CTD phosphatase 1; K17618 ubiquitin-like domain-containing CTD phosphatase 1 [EC:3.1.3.16] (A)	--	[K]	Transcription	NLI interacting factor-like phosphatase;; Ubiquitin family	Ubiquitin-like domain-containing CTD phosphatase 1 GN=UBLCP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ubiquitin-like domain-containing CTD phosphatase 1 [Erinaceus europaeus]
ENSG00000164338(UTP15)	--	10.758321	560	12.03226153	634	12.8210503	589	12.88064082	599	12.60342416	706	11.434519	567	0.971320192	0.066121494	normal	0.965746219	0.133457018	normal	0.971595116	-0.063045346	normal	0.879154087	0.048980352	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleolus (GO:0005730);; Biological Process: rRNA processing (GO:0006364);; 	K14549|0|ggo:101132539|UTP15; U3 small nucleolar RNA-associated protein 15 homolog isoform 1; K14549 U3 small nucleolar RNA-associated protein 15 (A)	Ribosome biogenesis in eukaryotes (ko03008)	[S]	Function unknown	"UTP15 C terminal;; WD domain, G-beta repeat"	U3 small nucleolar RNA-associated protein 15 homolog GN=UTP15 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: U3 small nucleolar RNA-associated protein 15 homolog [Ursus maritimus]
ENSG00000164342(TLR3)	--	0.787674499	36	1.1644854	68	0.447502198	24	3.051035253	120	2.365167735	100	2.514147192	94	3.91E-06	1.665017895	up	0.837217901	0.525280546	normal	2.88E-06	1.896514002	up	0.000819854	1.271312428	up	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K05401|0|hsa:7098|TLR3, CD283, IIAE2; toll-like receptor 3; K05401 toll-like receptor 3 (A)"	Toll-like receptor signaling pathway (ko04620);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; TIR domain;; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeat	Toll-like receptor 3 (Precursor) GN=TLR3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: toll-like receptor 3 [Galeopterus variegatus]
ENSG00000164346(NSA2)	--	34.5066	1441	37.2771	1630	35.6525	1554	39.079704	1704	35.697	1568	37.140078	1563	0.964041775	0.210815853	normal	0.982489163	-0.077299834	normal	0.984472171	3.98E-05	normal	0.875330728	0.042586125	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K14842|6.45515e-180|ptr:461806|NSA2; NSA2 ribosome biogenesis homolog (S. cerevisiae); K14842 ribosome biogenesis protein NSA2 (A)	--	[R]	General function prediction only	Ribosomal protein S8e	Ribosome biogenesis protein NSA2 homolog GN=NSA2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosome biogenesis protein NSA2 homolog [Dasypus novemcinctus]
ENSG00000164347(GFM2)	--	21.391084	1070	17.481879	831	20.241703	1021	22.755695	1081	19.388555	946	18.979868	922	0.980295909	-0.016053603	normal	0.96443941	0.165283088	normal	0.968195181	-0.15519364	normal	0.985016047	-0.008256301	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K02355|0|hsa:84340|GFM2, EF-G2mt, EFG2, MRRF2, MST027, RRF2, RRF2mt, hEFG2, mEF-G_2; G elongation factor, mitochondrial 2; K02355 elongation factor G (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	"Elongation factor Tu GTP binding domain;; Elongation Factor G, domain II;; Elongation factor G C-terminus;; Elongation factor G, domain IV;; Elongation factor Tu domain 2"	"Ribosome-releasing factor 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03059} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: ribosome-releasing factor 2, mitochondrial [Galeopterus variegatus]"
ENSG00000164362(TERT)	--	2.081607864	164	1.928591084	165	2.568979689	218	1.189301989	99	1.7405288	136	1.113987703	91	0.161453483	-0.749883701	normal	0.924134922	-0.297279545	normal	1.10E-05	-1.254779899	down	0.010554378	-0.767366553	normal	--	--	Molecular Function: RNA-directed DNA polymerase activity (GO:0003964);; 	K11126|0|ptr:101058547|TERT; telomerase reverse transcriptase; K11126 telomerase reverse transcriptase [EC:2.7.7.49] (A)	HTLV-I infection (ko05166)	[LB]	"Replication, recombination and repair;; Chromatin structure and dynamics"	Telomerase ribonucleoprotein complex - RNA binding domain;; Reverse transcriptase (RNA-dependent DNA polymerase)	Telomerase reverse transcriptase GN=TERT OS=Homo sapiens (Human) PE=1 SV=1	BL	"Chromatin structure and dynamics;; Replication, recombination and repair"	PREDICTED: telomerase reverse transcriptase isoform 1 [Odobenus rosmarus divergens]
ENSG00000164366(CCDC127)	--	4.057773618	508	4.759290939	631	3.078541209	514	3.536451	653	4.229212362	608	3.50285	645	0.857180712	0.330538571	normal	0.970934651	-0.074812564	normal	0.872866859	0.318401391	normal	0.428746443	0.183979136	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 127 GN=CCDC127 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 127 [Ceratotherium simum simum]
ENSG00000164379(FOXQ1)	--	8.28218	235	3.92415	114	6.73841	200	10.4695	304	10.5883	305	7.71755	224	0.869975904	0.338627337	normal	4.02E-08	1.386665125	up	0.956802105	0.154105703	normal	0.136877866	0.579906899	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09410|3.635e-151|hsa:94234|FOXQ1, HFH1; forkhead box Q1; K09410 forkhead box protein Q (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein Q1 GN=FOXQ1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: forkhead box protein Q1 [Eptesicus fuscus]
ENSG00000164398(ACSL6)	--	0.05786607	4	0.022096574	1	0.086901846	4	0.018910164	2	0.100551296	3	0.028358946	3	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01897|0|hsa:23305|ACSL6, ACS2, FACL6, LACS_6, LACS2, LACS5; acyl-CoA synthetase long-chain family member 6 (EC:6.2.1.3); K01897 long-chain acyl-CoA synthetase [EC:6.2.1.3] (A)"	Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	AMP-binding enzyme	Long-chain-fatty-acid--CoA ligase 6 GN=ACSL6 OS=Homo sapiens (Human) PE=2 SV=4	I	Lipid transport and metabolism	PREDICTED: long-chain-fatty-acid--CoA ligase 6 isoform X2 [Galeopterus variegatus]
ENSG00000164400(CSF2)	--	0.0916813	1	0	0	0	0	4.24968	48	1.78176	19	1.24983	14	3.94E-09	4.266605899	up	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: granulocyte macrophage colony-stimulating factor receptor binding (GO:0005129);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: growth factor activity (GO:0008083);; 	"K05427|7.79671e-90|hsa:1437|CSF2, GMCSF; colony stimulating factor 2 (granulocyte-macrophage); K05427 granulocyte-macrophage colony-stimulating factor (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Salmonella infection (ko05132);; Amoebiasis (ko05146);; HTLV-I infection (ko05166);; Transcriptional misregulation in cancer (ko05202);; Rheumatoid arthritis (ko05323)	--	--	Granulocyte-macrophage colony-stimulating factor	Granulocyte-macrophage colony-stimulating factor (Precursor) GN=CSF2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: granulocyte-macrophage colony-stimulating factor [Ceratotherium simum simum]
ENSG00000164402(SEPT8)	--	15.41776305	1152	12.07323018	971	15.23391106	1115	17.47457851	1417	17.24938149	1405	15.63185542	1216	0.934703812	0.26754459	normal	0.311642548	0.510935392	normal	0.976057078	0.116656527	normal	0.078477322	0.297053641	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K16939|0|mcf:101926198|uncharacterized LOC101926198; K16939 septin 6/8/11 (A)	Bacterial invasion of epithelial cells (ko05100)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Septin;; 50S ribosome-binding GTPase	Septin-8 GN=SEPT8 OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: septin-8 isoform X4 [Mustela putorius furo]
ENSG00000164403(SHROOM1)	--	5.72179658	334	6.473137799	328	6.474687578	343	5.420706474	293	5.713272408	293	4.36360977	233	0.93993379	-0.218704553	normal	0.949154201	-0.183326816	normal	0.311367873	-0.563138431	normal	0.225800461	-0.316993831	normal	--	--	Molecular Function: actin filament binding (GO:0051015);; 	"K18625|0|hsa:134549|SHROOM1, APXL2; shroom family member 1; K18625 protein Shroom (A)"	Tight junction (ko04530)	--	--	Apx/Shroom domain ASD2;; Apx/Shroom domain ASD1	Protein Shroom1 GN=SHROOM1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: protein Shroom1 [Lipotes vexillifer]
ENSG00000164404(GDF9)	--	0.603532476	21	0.201022384	7	0.461756047	19	0.161677	7	0.135124071	4	0.274439	10	0.822579826	-1.427557915	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K05498|0|ptr:471630|GDF9, AFF4; growth differentiation factor 9; K05498 growth differentiation factor 9/9B (A)"	Ovarian steroidogenesis (ko04913)	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain	Growth/differentiation factor 9 (Precursor) GN=GDF9 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: growth/differentiation factor 9 [Galeopterus variegatus]
ENSG00000164405(UQCRQ)	--	113.320994	925	131.67667	1129	137.23536	1156	161.4990627	1435	131.480214	1173	158.57253	1437	0.058635344	0.601884733	normal	0.980328851	0.033686701	normal	0.905553092	0.305268368	normal	0.084201127	0.312465039	normal	--	--	--	K00418|5.26503e-54|ptr:471631|UQCRQ; cytochrome b-c1 complex subunit 8; K00418 ubiquinol-cytochrome c reductase subunit 8 (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	UcrQ family	Cytochrome b-c1 complex subunit 8 GN=UQCRQ OS=Homo sapiens (Human) PE=1 SV=4	C	Energy production and conversion	PREDICTED: cytochrome b-c1 complex subunit 8-like [Dasypus novemcinctus] 
ENSG00000164411(GJB7)	--	0	0	0.0915875	3	0	0	0	0	0	0	0.0300874	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07626|1.18731e-161|hsa:375519|GJB7, CX25, bA136M9.1, connexin25; gap junction protein, beta 7, 25kDa; K07626 gap junction protein, beta 7 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction beta-7 protein GN=GJB7 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: gap junction beta-7 protein [Balaenoptera acutorostrata scammoni]
ENSG00000164414(SLC35A1)	--	8.568354965	221	7.651536881	196	7.655608159	192	8.515398945	222	7.536097805	196	8.42440848	218	0.966757212	-0.024151432	normal	0.965670749	-0.021262504	normal	0.953827533	0.173646039	normal	0.93870179	0.041166361	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K15272|0|ptr:462874|SLC35A1; solute carrier family 35 (CMP-sialic acid transporter), member A1; K15272 solute carrier family 35 (UDP-sugar transporter), member A1/2/3 (A)"	--	[G]	Carbohydrate transport and metabolism	Nucleotide-sugar transporter;; UAA transporter family;; Triose-phosphate Transporter family	CMP-sialic acid transporter GN=SLC35A1 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: CMP-sialic acid transporter isoform X1 [Pantholops hodgsonii]
ENSG00000164418(GRIK2)	--	0.288356415	3	0.082311574	1	0	0	0.47291627	30	0.225308924	18	0.48266067	23	0.0026499	2.772525696	up	--	--	--	0.000616501	4.014815783	up	--	--	--	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05202|0|ptr:462899|GRIK2, GRIK5; glutamate receptor, ionotropic, kainate 2; K05202 glutamate receptor, ionotropic kainate 2 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Receptor family ligand binding region;; Ligand-gated ion channel;; Ligated ion channel L-glutamate- and glycine-binding site;; Bacterial extracellular solute-binding proteins, family 3;; Periplasmic binding protein"	"Glutamate receptor ionotropic, kainate 2 (Precursor) GN=GRIK2 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, kainate 2-like isoform X1 [Chrysochloris asiatica]"
ENSG00000164430(MB21D1)	--	3.383988841	177	4.202966838	219	3.482408254	181	5.648683249	299	6.754508083	355	5.95555446	314	0.05163844	0.720700451	normal	0.080626087	0.671785104	normal	0.01604102	0.781465372	normal	0.001530579	0.725263998	normal	--	--	--	"K17834|0|hsa:115004|MB21D1, C6orf150, cGAS, h-cGAS; Mab-21 domain containing 1 (EC:2.7.7.86); K17834 cyclic GMP-AMP synthase [EC:2.7.7.86] (A)"	Cytosolic DNA-sensing pathway (ko04623)	--	--	Mab-21 protein	Cyclic GMP-AMP synthase GN=MB21D1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cyclic GMP-AMP synthase [Leptonychotes weddellii]
ENSG00000164440(TXLNB)	--	0	0	0	0	0	0	0.00961182	1	0.0186635	1	0.0286569	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: syntaxin binding (GO:0019905);; 	--	--	[Z]	Cytoskeleton	Myosin-like coiled-coil protein	Beta-taxilin GN=TXLNB OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: beta-taxilin [Galeopterus variegatus]
ENSG00000164442(CITED2)	--	16.26739301	555	20.99183411	698	20.11479198	684	12.1823677	434	10.21521542	344	17.51793855	634	0.766740467	-0.384418017	normal	2.49E-06	-1.038968883	down	0.968335241	-0.117534937	normal	0.18329784	-0.476058488	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	CITED	Cbp/p300-interacting transactivator 2 GN=CITED2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cbp/p300-interacting transactivator 2-like [Mustela putorius furo]
ENSG00000164463(CREBRF)	--	1.490416093	159	2.061236	259	1.52864474	178	1.4492829	176	1.18367909	150	2.841107926	336	0.962776558	0.11466302	normal	0.021393356	-0.803174051	normal	0.001238278	0.902619482	normal	0.900377638	0.131924529	normal	--	--	--	--	--	--	--	bZIP transcription factor	CREB3 regulatory factor GN=CREBRF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CREB3 regulatory factor isoform X1 [Sus scrofa] 
ENSG00000164465(DCBLD1)	--	25.27533	1616	31.22343	2041	28.57948	1823	35.75437	2328	40.79067	2641	40.41053	2638	0.36920701	0.495437221	normal	0.882829867	0.350152927	normal	0.2538019	0.524474884	normal	0.00223734	0.452317434	normal	--	--	--	--	--	--	--	F5/8 type C domain;; CUB domain;; LCCL domain	"Discoidin, CUB and LCCL domain-containing protein 1 (Precursor) GN=DCBLD1 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: discoidin, CUB and LCCL domain-containing protein 1 [Equus caballus]"
ENSG00000164466(SFXN1)	--	38.72275843	2328	37.43981094	2144	40.74232774	2276	33.4370423	2169	32.34671494	2058	27.74453915	1683	0.982892811	-0.132802436	normal	0.985280311	-0.08043057	normal	0.60508224	-0.443412853	normal	0.233818761	-0.213158049	normal	--	--	Biological Process: ion transport (GO:0006811);; Molecular Function: ion transmembrane transporter activity (GO:0015075);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Tricarboxylate carrier	Sideroflexin-1 GN=SFXN1 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: sideroflexin-1 [Leptonychotes weddellii]
ENSG00000164483(SAMD3)	--	0.028033676	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Sterile alpha motif domain-containing protein 3 GN=SAMD3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: sterile alpha motif domain-containing protein 3 [Ceratotherium simum simum]
ENSG00000164484(TMEM200A)	--	0.092524138	5	0	0	0.022967725	0	0.137429262	7	0.066660421	2	0.0689118	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2371)	Transmembrane protein 200A GN=TMEM200A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 200A [Loxodonta africana]
ENSG00000164485(IL22RA2)	--	0.026188944	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05139|0|hsa:116379|IL22RA2, CRF2-10, CRF2-S1, CRF2X, IL-22BP, IL-22R-alpha-2, IL-22RA2, ZCYTOR16; interleukin 22 receptor, alpha 2; K05139 interleukin 22 receptor alpha 2 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	"Tissue factor;; Interferon-alpha/beta receptor, fibronectin type III"	Interleukin-22 receptor subunit alpha-2 (Precursor) GN=IL22RA2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-22 receptor subunit alpha-2 [Galeopterus variegatus]
ENSG00000164488(DACT2)	--	0.031240244	1	0	0	0	0	0.065337187	4	0.215717037	11	0.412273952	23	--	--	--	--	--	--	0.000616501	4.014815783	up	--	--	--	--	--	--	--	--	--	--	Dapper	Dapper homolog 2 GN=DACT2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: dapper homolog 2 [Galeopterus variegatus]
ENSG00000164494(PDSS2)	--	16.93629861	338	6.158344172	290	7.490087393	314	9.688888526	410	9.896809522	433	7.66673661	386	0.928011992	0.246748785	normal	0.289453879	0.554506581	normal	0.904359755	0.288290472	normal	0.120712638	0.362396976	normal	[H]	Coenzyme transport and metabolism	Biological Process: isoprenoid biosynthetic process (GO:0008299);; 	"K12505|0|hsa:57107|PDSS2, C6orf210, COQ10D3, DLP1, bA59I9.3, hDLP1; prenyl (decaprenyl) diphosphate synthase, subunit 2 (EC:2.5.1.91); K12505 decaprenyl-diphosphate synthase subunit 2 [EC:2.5.1.91] (A)"	Terpenoid backbone biosynthesis (ko00900)	[H]	Coenzyme transport and metabolism	Polyprenyl synthetase	Decaprenyl-diphosphate synthase subunit 2 GN=PDSS2 OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: decaprenyl-diphosphate synthase subunit 2 [Camelus ferus]
ENSG00000164506(STXBP5)	--	5.768754975	687	5.490413982	706	7.654608151	777	7.494798322	900	10.23497744	1131	7.382874439	862	0.81510166	0.358081187	normal	0.023580002	0.657310239	normal	0.967966828	0.141220768	normal	0.043619849	0.393889	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08518|0|hsa:134957|STXBP5, LGL3, LLGL3, Nbla04300; syntaxin binding protein 5 (tomosyn); K08518 syntaxin-binding protein 5 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"LLGL2;; WD domain, G-beta repeat;; Lethal giant larvae(Lgl) like, C-terminal"	Syntaxin-binding protein 5 GN=STXBP5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-binding protein 5 isoform X1 [Leptonychotes weddellii]
ENSG00000164509(IL31RA)	--	0.644243277	82	0.583444663	56	0.936794042	113	2.810841045	352	2.11846615	288	2.14888121	255	0	2.050899128	up	0	2.310593532	up	2.79E-05	1.155313266	up	3.37E-11	1.813002783	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Fibronectin type III domain;; Interleukin-6 receptor alpha chain, binding;; Erythropoietin receptor, ligand binding"	Interleukin-31 receptor subunit alpha (Precursor) GN=IL31RA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: interleukin-31 receptor subunit alpha [Ceratotherium simum simum]
ENSG00000164512(ANKRD55)	--	0.173038403	5	0	0	0.0689896	1	0.0688979	2	0.06617267	2	0.022100997	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 55 GN=ANKRD55 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 55 [Loxodonta africana]
ENSG00000164520(RAET1E)	--	0.252465672	11	0.649463733	15	0.60744909	27	1.450338721	58	1.077292948	48	1.350290449	36	5.21E-05	2.219097709	up	0.040127874	1.564128576	normal	0.974116346	0.387875024	normal	0.007852684	1.40060306	up	--	--	--	K07987|1.77824e-167|ptr:463064|RAET1E; retinoic acid early transcript 1E; K07987 retinoic acid early transcript 1 (A)	Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2;; Class I Histocompatibility antigen, domains alpha 1 and 2"	NKG2D ligand 4 (Precursor) GN=RAET1E OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: NKG2D ligand 4 isoform X2 [Camelus dromedarius]
ENSG00000164530(PI16)	--	0	0	0	0	0	0	0.024413744	1	0	0	0.048212209	2	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family	Peptidase inhibitor 16 (Precursor) GN=PI16 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: peptidase inhibitor 16 isoform 1 [Orcinus orca] 
ENSG00000164532(TBX20)	--	1.49054866	134	1.73787936	152	1.755672774	151	1.349085222	121	1.399762115	125	0.995146401	87	0.959252664	-0.175934111	normal	0.926521086	-0.30026958	normal	0.132560488	-0.793155324	normal	0.27146356	-0.414065333	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10185|0|pon:100459652|TBX20; T-box 20; K10185 T-box protein 20 (A)	--	[K]	Transcription	T-box	T-box transcription factor TBX20 GN=TBX20 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: T-box transcription factor TBX20-like [Ochotona princeps]
ENSG00000164542(KIAA0895)	--	6.008910381	303	6.949921	364	7.629763	337	6.652133	341	6.227373018	318	7.060935001	376	0.958747825	0.138957247	normal	0.940109314	-0.215380018	normal	0.957670919	0.149059086	normal	0.962920831	0.022918923	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF1704)	Uncharacterized protein KIAA0895 GN=KIAA0895 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: uncharacterized protein KIAA0895 isoform X1 [Canis lupus familiaris]
ENSG00000164543(STK17A)	--	31.6273	1407	23.96568	1108	29.0052	1283	33.0779	1495	40.0254	1742	44.4436	1903	0.9826685	0.056630897	normal	0.035923487	0.630668222	normal	0.131281497	0.559917635	normal	0.026748158	0.416169425	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08804|0|hsa:9263|STK17A, DRAK1; serine/threonine kinase 17a (EC:2.7.11.1); K08804 serine/threonine kinase 17 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase 17A GN=STK17A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 17A isoform X1 [Oryctolagus cuniculus]
ENSG00000164548(TRA2A)	--	29.50315412	874	36.13969065	1088	38.89760846	1140	37.1335855	1117	35.2446567	1057	38.08869661	1164	0.876537145	0.322589078	normal	0.978448932	-0.063040832	normal	0.981061109	0.021737254	normal	0.728423576	0.084924186	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12897|1.21628e-79|ecb:100068009|TRA2A; transformer 2 alpha homolog (Drosophila); K12897 transformer-2 protein (A)	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Transformer-2 protein homolog alpha GN=TRA2A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: transformer-2 protein homolog alpha [Equus caballus]
ENSG00000164574(GALNT10)	--	72.86000045	8805	69.12640854	8308	75.58370661	9049	89.67171194	10618	100.4668956	11928	71.22121402	8396	0.987213646	0.239246815	normal	0.604063686	0.500276105	normal	0.99440528	-0.116327457	normal	0.359523571	0.220480537	normal	--	--	--	"K00710|0|hsa:55568|GALNT10, GALNACT10, PPGALNACT10, PPGANTASE10; polypeptide N-acetylgalactosaminyltransferase 10 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 10 GN=GALNT10 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 10 [Orcinus orca]
ENSG00000164576(SAP30L)	--	7.712117	842	7.745856001	835	8.421445	898	7.995597	839	7.425958	808	7.865413	844	0.977011982	-0.035916032	normal	0.974814666	-0.068720929	normal	0.974026044	-0.097594325	normal	0.798499626	-0.068907886	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SAP30 zinc-finger;; Sin3 binding region of histone deacetylase complex subunit SAP30	Histone deacetylase complex subunit SAP30L GN=SAP30L OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: histone deacetylase complex subunit SAP30L [Canis lupus familiaris]
ENSG00000164587(RPS14)	--	1031.176989	14970	1085.516852	15261	1043.34406	14471	1152.63772	16778	1119.069536	16058	988.497048	14666	0.996296062	0.133651305	normal	0.997154884	0.052011136	normal	0.99724511	0.011018238	normal	0.816629057	0.065985754	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02955|2.59127e-98|xtr:549476|uncharacterized LOC549476; K02955 small subunit ribosomal protein S14e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S11	40S ribosomal protein S14 GN=RPS14 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 40S ribosomal protein S14-like, partial [Bubalus bubalis]"
ENSG00000164591(MYOZ3)	--	0.295278208	6	0.382515636	12	0.131455386	4	0.173701121	3	0.016674797	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Calcineurin-binding protein (Calsarcin)	Myozenin-3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: myozenin-3 isoform X1 [Equus caballus]
ENSG00000164597(COG5)	--	15.408503	1083	17.8424	1119	16.257875	1072	17.4927989	1087	16.14738512	1091	15.33582	1112	0.980257212	-0.025477489	normal	0.979046751	-0.057906233	normal	0.979908788	0.044498802	normal	0.968208131	-0.014139989	normal	--	--	Biological Process: intra-Golgi vesicle-mediated transport (GO:0006891);; Cellular Component: Golgi transport complex (GO:0017119);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Golgi transport complex subunit 5;; Vps51/Vps67	Conserved oligomeric Golgi complex subunit 5 GN=COG5 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: conserved oligomeric Golgi complex subunit 5 [Ceratotherium simum simum]
ENSG00000164603(BMT2)	--	5.439821761	272	6.150816025	313	4.980132556	264	7.553469023	357	5.83435878	314	5.826916439	315	0.836355222	0.359707057	normal	0.966989358	-0.016743887	normal	0.930590624	0.245234858	normal	0.520746173	0.194004066	normal	--	--	Molecular Function: rRNA (adenine) methyltransferase activity (GO:0016433);; 	--	--	--	--	Putative methyltransferase (DUF3321)	Probable methyltransferase BTM2 homolog {ECO:0000255|HAMAP-Rule:MF_03044} GN=C7orf60 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0532 protein C7orf60 homolog [Ceratotherium simum simum]
ENSG00000164604(GPR85)	--	0.083419953	3	0.146350191	6	0.024427	0	0.024218654	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04302|0|umr:103659007|GPR85; G protein-coupled receptor 85; K04302 G protein-coupled receptor 85 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 85 GN=GPR85 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: probable G-protein coupled receptor 85 [Trichechus manatus latirostris] 
ENSG00000164609(SLU7)	--	14.484021	854	16.15789734	923	17.08549603	968	13.2505697	875	14.793374	874	14.270685	931	0.977843435	0.004207206	normal	0.973673168	-0.099955596	normal	0.977410831	-0.0644147	normal	0.840945713	-0.055442674	normal	--	--	--	"K12819|0|hsa:10569|SLU7, 9G8, hSlu7; SLU7 splicing factor homolog (S. cerevisiae); K12819 pre-mRNA-processing factor SLU7 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Pre-mRNA splicing Prp18-interacting factor	Pre-mRNA-splicing factor SLU7 GN=SLU7 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: pre-mRNA-splicing factor SLU7 [Panthera tigris altaica]
ENSG00000164610(RP9)	--	9.740250138	239	10.9415003	271	10.72240044	265	11.21730065	279	12.38480017	303	12.50190044	308	0.948635448	0.191283313	normal	0.957457037	0.138865259	normal	0.943982877	0.207546973	normal	0.579236144	0.178782323	normal	--	--	--	--	--	[K]	Transcription	--	Retinitis pigmentosa 9 protein GN=RP9 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: retinitis pigmentosa 9 protein isoform X1 [Mustela putorius furo]
ENSG00000164611(PTTG1)	--	116.588877	1266	93.34499945	1000	113.393674	1215	101.8581022	1124	96.23582327	1039	81.807036	898	0.961063552	-0.202206985	normal	0.978894406	0.03371907	normal	0.568438142	-0.443815316	normal	0.312281383	-0.207172024	normal	--	--	Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: chromosome organization (GO:0051276);; 	"K06635|6.06778e-133|hsa:9232|PTTG1, EAP1, HPTTG, PTTG, TUTR1; pituitary tumor-transforming 1; K06635 securin (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; HTLV-I infection (ko05166)	--	--	Securin sister-chromatid separation inhibitor	Securin GN=PTTG1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: securin isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000164615(CAMLG)	--	17.583302	542	14.48802	452	17.40385	538	19.63175	542	20.042785	608	18.515995	518	0.972148868	-0.03074511	normal	0.722121627	0.40514941	normal	0.970633602	-0.062765699	normal	0.722163476	0.101637034	normal	--	--	--	--	--	--	--	Calcium signal-modulating cyclophilin ligand	Calcium signal-modulating cyclophilin ligand GN=CAMLG OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: calcium signal-modulating cyclophilin ligand isoform X1 [Equus przewalskii]
ENSG00000164619(BMPER)	--	15.337582	1110	9.4924588	720	11.56269	828	5.3429883	383	3.94988954	264	2.532223468	186	2.22E-16	-1.562112284	down	1.10E-12	-1.463588412	down	0	-2.153528657	down	6.63E-06	-1.69742689	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type D domain;; von Willebrand factor type C domain;; C8 domain;; Trypsin Inhibitor like cysteine rich domain	BMP-binding endothelial regulator protein (Precursor) GN=BMPER OS=Homo sapiens (Human) PE=1 SV=3	VW	Defense mechanisms;; Extracellular structures	PREDICTED: BMP-binding endothelial regulator protein [Oryctolagus cuniculus]
ENSG00000164620(RELL2)	--	2.328806621	116	2.510721091	117	2.404750405	118	1.613055015	74	1.576961617	74	1.79563193	83	0.549441121	-0.668180338	normal	0.536111646	-0.671328612	normal	0.816732073	-0.508090729	normal	0.106981878	-0.624413582	normal	--	--	--	--	--	--	--	Tumour necrosis factor receptor superfamily member 19	RELT-like protein 2 GN=RELL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RELT-like protein 2 isoform X1 [Tupaia chinensis] 
ENSG00000164626(KCNK5)	--	0.759781609	54	0.765116976	56	0.723482416	53	1.147202445	78	1.445233954	104	0.638286675	47	0.908571994	0.48807303	normal	0.235577102	0.854477574	normal	0.975433668	-0.176278446	normal	0.424314758	0.468246832	normal	[P]	Inorganic ion transport and metabolism	--	"K04916|0|ptr:462666|KCNK5; potassium channel, subfamily K, member 5; K04916 potassium channel subfamily K member 5 (A)"	Protein digestion and absorption (ko04974)	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 5 GN=KCNK5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 5 [Orcinus orca]
ENSG00000164627(KIF6)	--	0.698037001	18	0.313040037	8	0.660087334	21	0.307835	8	0.445850901	11	0.153082	4	--	--	--	--	--	--	0.35980469	-2.036865402	normal	--	--	--	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10397|0|pps:100985225|KIF6; kinesin family member 6; K10397 kinesin family member 6/9 (A)	--	--	--	Kinesin motor domain	Kinesin-like protein KIF6 GN=KIF6 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF6 [Balaenoptera acutorostrata scammoni]
ENSG00000164631(ZNF12)	--	8.120492909	746	8.092151089	744	6.727290378	610	7.632304	707	7.07314388	649	7.321389314	671	0.970546778	-0.108069	normal	0.945689813	-0.218035743	normal	0.966471953	0.128907272	normal	0.799031518	-0.072764584	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100969518|ZNF12; zinc finger protein 12; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 12 GN=ZNF12 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 12 isoform X1 [Tupaia chinensis]
ENSG00000164638(SLC29A4)	--	30.670142	1678	22.9186411	1297	24.5197729	1432	12.594959	673	17.2448749	923	12.57382268	723	3.61E-13	-1.346877806	down	0.308419752	-0.511491822	normal	9.12E-07	-0.992750622	normal	2.06E-06	-0.947149355	normal	--	--	Molecular Function: nucleoside transmembrane transporter activity (GO:0005337);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	"K03323|0|hsa:222962|SLC29A4, ENT4, PMAT; solute carrier family 29 (equilibrative nucleoside transporter), member 4; K03323 solute carrier family 29 (equilibrative nucleoside transporter), member 4 (A)"	--	[F]	Nucleotide transport and metabolism	Nucleoside transporter	Equilibrative nucleoside transporter 4 GN=SLC29A4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: equilibrative nucleoside transporter 4 [Tupaia chinensis]
ENSG00000164647(STEAP1)	--	29.42461163	566	16.88541071	328	23.26382	445	22.377614	437	29.75291452	569	21.44681431	413	0.722670518	-0.402752788	normal	0.004882671	0.770576698	normal	0.963933606	-0.115547284	normal	0.917992512	0.062634445	normal	--	--	--	"K14737|0|hsa:26872|STEAP1, PRSS24, STEAP; six transmembrane epithelial antigen of the prostate 1; K14737 metalloreductase STEAP1 [EC:1.16.1.-] (A)"	Mineral absorption (ko04978)	--	--	Ferric reductase like transmembrane component	Metalloreductase STEAP1 GN=STEAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: metalloreductase STEAP1 [Canis lupus familiaris]
ENSG00000164649(CDCA7L)	--	14.765399	827	15.3796781	858	15.80386285	865	13.193389	747	12.927572	719	10.98424945	570	0.960221506	-0.177264626	normal	0.917614614	-0.275880452	normal	0.065501366	-0.608708927	normal	0.053104304	-0.346657264	normal	--	--	--	--	--	--	--	Zinc-finger domain of monoamine-oxidase A repressor R1	Cell division cycle-associated 7-like protein GN=CDCA7L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cell division cycle-associated 7-like protein [Leptonychotes weddellii]
ENSG00000164651(SP8)	--	0	0	0	0	0	0	0	0	0.051413061	1	0.021409408	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09198|0|hsa:221833|SP8, BTD; Sp8 transcription factor; K09198 transcription factor Sp8 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Transcription factor Sp8 GN=SP8 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: transcription factor Sp8 isoform X1 [Chrysochloris asiatica]
ENSG00000164654(MIOS)	--	8.559230531	508	10.035835	510	10.52182323	532	10.416672	589	11.231471	549	9.33855	506	0.953947518	0.182095075	normal	0.968363434	0.084640413	normal	0.969269468	-0.080346084	normal	0.840739223	0.06337487	normal	--	--	--	--	--	[S]	Function unknown	--	WD repeat-containing protein mio GN=MIOS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein mio isoform X2 [Ursus maritimus]
ENSG00000164659(KIAA1324L)	--	0.227177609	15	0.167322455	12	0.109718249	7	0.036614401	2	0.047169771	3	0.156258702	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	GCC2 and GCC3	UPF0577 protein KIAA1324-like (Precursor) GN=KIAA1324L OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: UPF0577 protein KIAA1324-like homolog isoform X1 [Oryctolagus cuniculus]
ENSG00000164663(USP49)	--	1.83245197	235	2.085955	256	1.899444	249	1.8396179	262	1.9043059	248	2.022768	224	0.960222012	0.125297728	normal	0.964255873	-0.06682912	normal	0.955404269	-0.159913938	normal	0.950044159	-0.03338672	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11834|0|hsa:25862|USP49; ubiquitin specific peptidase 49 (EC:3.4.19.12); K11834 ubiquitin carboxyl-terminal hydrolase 44/49 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 49 GN=USP49 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 49 [Galeopterus variegatus]
ENSG00000164674(SYTL3)	--	0.782651601	38	0.69651854	44	0.841735764	43	1.583901794	67	1.808693107	77	2.246302334	99	0.726355692	0.763800164	normal	0.628838888	0.765798125	normal	0.013302112	1.1670081	normal	0.032041459	0.93906911	normal	--	--	--	K17598|0|pps:100984261|SYTL3; synaptotagmin-like 3; K17598 synaptotagmin-like protein (A)	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; FYVE-type zinc finger	Synaptotagmin-like protein 3 GN=SYTL3 OS=Homo sapiens (Human) PE=2 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-like protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000164675(IQUB)	--	0.0724312	4	0.038544418	2	0.053126	2	0.0702648	4	0.0491271	2	0.033539845	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ubiquitin family	IQ and ubiquitin-like domain-containing protein GN=IQUB OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: IQ and ubiquitin-like domain-containing protein [Galeopterus variegatus]
ENSG00000164683(HEY1)	--	0.0930636	3	0	0	0.184648294	5	0.16229656	6	0.3829113	13	0.380719823	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K09091|2.03592e-177|ptr:464248|HEY1; hes-related family bHLH transcription factor with YRPW motif 1; K09091 hairy and enhancer of split related with YRPW motif (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain;; Hairy Orange	Hairy/enhancer-of-split related with YRPW motif protein 1 GN=HEY1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hairy/enhancer-of-split related with YRPW motif protein 1 isoform X2 [Sus scrofa]
ENSG00000164684(ZNF704)	--	4.226117628	510	5.852403	643	3.297091492	444	3.224192	320	5.190591	463	2.70675581	366	0.020873705	-0.700566998	normal	0.421597133	-0.493857644	normal	0.904380425	-0.285933046	normal	0.118945821	-0.496145053	normal	--	--	--	--	--	--	--	--	Zinc finger protein 704 GN=ZNF704 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 704 [Tupaia chinensis]
ENSG00000164687(FABP5)	--	96.342557	1214	100.262339	1323	95.796934	1265	116.018345	1536	91.487041	1150	68.555469	887	0.904374618	0.308230077	normal	0.955113529	-0.223331678	normal	0.256597329	-0.519676876	normal	0.800513651	-0.112521891	normal	--	--	--	"K08754|2.62088e-94|ptr:746909|FABP5, FABP5L2, FABP5L7; fatty acid binding protein 5 (psoriasis-associated); K08754 fatty acid-binding protein 5, epidermal (A)"	PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family	"Fatty acid-binding protein, epidermal GN=FABP5 OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: fatty acid-binding protein, epidermal [Galeopterus variegatus]"
ENSG00000164690(SHH)	--	0.835648064	55	0.8219556	53	0.729824174	51	0.49455777	33	1.015841699	39	0.372674782	24	0.826550399	-0.74078862	normal	0.948938252	-0.448951357	normal	0.48764171	-1.049389072	normal	0.168175461	-0.749894626	normal	--	--	Biological Process: proteolysis (GO:0006508);; Biological Process: cell-cell signaling (GO:0007267);; Molecular Function: peptidase activity (GO:0008233);; 	"K11988|0|hsa:6469|SHH, HHG1, HLP3, HPE3, MCOPCB5, SMMCI, TPT, TPTPS; sonic hedgehog; K11988 sonic hedgehog (A)"	Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Hedgehog amino-terminal signalling domain;; Hint module	Sonic hedgehog protein C-product (Precursor) GN=SHH OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: sonic hedgehog protein [Odobenus rosmarus divergens]
ENSG00000164692(COL1A2)	--	0.011570645	1	0.00940678	1	0.022080245	1	0.03456952	3	0.022699424	1	0.058836886	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; 	"K06236|0|ggo:101142769|COL1A2; collagen alpha-2(I) chain; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain	Collagen alpha-2(I) chain (Precursor) GN=COL1A2 OS=Homo sapiens (Human) PE=1 SV=7	W	Extracellular structures	PREDICTED: collagen alpha-2(I) chain [Ailuropoda melanoleuca]
ENSG00000164694(FNDC1)	--	0.029650079	4	0.067173303	9	0.0290323	3	0.037467406	5	0.100408864	13	0.021956088	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Fibronectin type III domain;; Interferon-alpha/beta receptor, fibronectin type III"	Fibronectin type III domain-containing protein 1 (Precursor) GN=FNDC1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: fibronectin type III domain-containing protein 1 isoform X5 [Canis lupus familiaris]
ENSG00000164695(CHMP4C)	--	4.92513	175	4.67845	168	5.83624	208	6.80255	244	6.82912	242	6.31797	226	0.745354198	0.445369422	normal	0.624495768	0.501340262	normal	0.962011876	0.110675645	normal	0.251337541	0.348786971	normal	--	--	Biological Process: vacuolar transport (GO:0007034);; 	"K12194|6.38227e-114|hsa:92421|CHMP4C, SNF7-3, Shax3, VPS32C; charged multivesicular body protein 4C; K12194 charged multivesicular body protein 4 (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snf7	Charged multivesicular body protein 4c GN=CHMP4C OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 4c [Tupaia chinensis] 
ENSG00000164707(SLC13A4)	--	0.041041069	2	0	0	0	0	0.061686857	3	0.019991516	0	0.0406636	2	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14444|0|nle:100591182|SLC13A4; solute carrier family 13 (sodium/sulfate symporters), member 4; K14444 solute carrier family 13 (sodium/sulfate cotransporter), member 1/4 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:sulfate symporter transmembrane region;; Citrate transporter;; DctM-like transporters	Solute carrier family 13 member 4 GN=SLC13A4 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 13 member 4 [Ceratotherium simum simum]
ENSG00000164708(PGAM2)	--	1.28449	18	1.26622	18	0.203909	2	0.416363	6	1.7214	24	1.32984	19	--	--	--	0.98298743	0.366848186	normal	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	--	"K01834|0|ptr:737767|PGAM2; phosphoglycerate mutase 2 (muscle); K01834 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; Central carbon metabolism in cancer (ko05230)"	[G]	Carbohydrate transport and metabolism	Histidine phosphatase superfamily (branch 1)	Phosphoglycerate mutase 2 GN=PGAM2 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: phosphoglycerate mutase 2 [Ailuropoda melanoleuca] 
ENSG00000164713(BRI3)	--	297.9065308	1911	314.2550729	2227	306.6991005	2080	293.897329	2227	261.1939894	1842	398.63645	2805	0.974054753	0.18980006	normal	0.932608789	-0.295034382	normal	0.705247068	0.422860104	normal	0.743470062	0.124116402	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2367)	Brain protein I3 GN=BRI3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: brain protein I3 [Oryctolagus cuniculus]
ENSG00000164715(LMTK2)	--	8.86644	1612	9.55437	1736	8.07549	1470	8.96243	1625	8.59625	1560	8.64116	1575	0.984720231	-0.019226038	normal	0.972796674	-0.175486116	normal	0.981527031	0.091153621	normal	0.889273613	-0.039009735	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08898|0|hsa:22853|LMTK2, AATYK2, BREK, KPI-2, KPI2, LMR2, PPP1R100, cprk; lemur tyrosine kinase 2 (EC:2.7.11.1); K08898 lemur tyrosine kinase 2 [EC:2.7.10.1] (A)"	--	--	--	Protein tyrosine kinase;; Protein kinase domain	Serine/threonine-protein kinase LMTK2 GN=LMTK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase LMTK2 [Ursus maritimus]
ENSG00000164733(CTSB)	--	302.4901694	13206	292.1155309	12107	305.802561	12763	343.3020226	15365	369.6676957	16504	466.5891716	20606	0.99414701	0.187601704	normal	0.891234665	0.425502059	normal	0.020164884	0.682741293	normal	0.031477225	0.442470061	normal	--	--	Molecular Function: cysteine-type endopeptidase activity (GO:0004197);; Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; Biological Process: regulation of catalytic activity (GO:0050790);; 	"K01363|0|hsa:1508|CTSB, APPS, CPSB; cathepsin B (EC:3.4.22.1); K01363 cathepsin B [EC:3.4.22.1] (A)"	Lysosome (ko04142);; Antigen processing and presentation (ko04612)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Peptidase family C1 propeptide	Cathepsin B heavy chain (Precursor) GN=CTSB OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin B isoform 1 [Ceratotherium simum simum] 
ENSG00000164736(SOX17)	--	1.22016	43	0.830242	30	0.964858	35	1.25654	45	1.03305	37	0.801928	29	0.980647974	0.033583094	normal	0.977734949	0.268912587	normal	0.979752248	-0.266905968	normal	0.999113997	0.017023106	normal	--	--	--	"K04495|0|hsa:64321|SOX17, VUR3; SRY (sex determining region Y)-box 17; K04495 transcription factor SOX17 (SOX group F) (A)"	Wnt signaling pathway (ko04310)	[K]	Transcription	Sox C-terminal transactivation domain;; HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-17 GN=SOX17 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor SOX-17-like [Sus scrofa]
ENSG00000164741(DLC1)	--	7.651051	924	6.915593963	840	11.03077557	1140	2.8478847	332	2.40206223	283	2.02438412	234	1.23E-14	-1.503180953	down	2.22E-15	-1.58584373	down	0	-2.285331476	down	2.36E-14	-1.795952768	down	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Molecular Function: lipid binding (GO:0008289);; 	--	--	[T]	Signal transduction mechanisms	START domain;; RhoGAP domain;; SAM domain (Sterile alpha motif)	Rho GTPase-activating protein 7 GN=DLC1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 7 isoform 1 [Ceratotherium simum simum]
ENSG00000164742(ADCY1)	--	1.9687408	235	1.537968104	246	1.832178669	272	3.497767917	603	2.862475399	459	3.124536232	514	4.91E-10	1.323073754	up	0.000877849	0.874413577	normal	0.000225054	0.906144807	normal	1.86E-08	1.043964555	up	[T]	Signal transduction mechanisms	Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	K08041|0|ptr:463392|ADCY1; adenylate cyclase 1 (brain); K08041 adenylate cyclase 1 [EC:4.6.1.1] (A)	Purine metabolism (ko00230);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; GABAergic synapse (ko04727);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Morphine addiction (ko05032);; Chagas disease (American trypanosomiasis) (ko05142);; Amoebiasis (ko05146);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[C]	Energy production and conversion	Adenylate and Guanylate cyclase catalytic domain	Adenylate cyclase type 1 GN=ADCY1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	adenylate cyclase type 1 [Bos taurus] 
ENSG00000164743(C8orf48)	--	0.676754	18	1.21165	32	0.969286	25	0.523101	14	0.255015	6	0.520067	14	--	--	--	0.017800383	-2.176153595	normal	0.95806551	-0.780900502	normal	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4606)	Uncharacterized protein C8orf48 GN=C8orf48 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C8orf48 homolog [Ceratotherium simum simum]
ENSG00000164744(SUN3)	--	0	0	0.086781229	1	0	0	0	0	0.288381326	1	0.138778909	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Sad1 / UNC-like C-terminal	SUN domain-containing protein 3 GN=SUN3 OS=Homo sapiens (Human) PE=2 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: SUN domain-containing protein 3 [Leptonychotes weddellii]
ENSG00000164746(C7orf57)	--	0.033520099	1	0.1338719	4	0	0	0.0293367	1	0	0	0.02888324	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C7orf57 GN=C7orf57 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C7orf57 homolog isoform X1 [Tupaia chinensis]
ENSG00000164749(HNF4G)	--	0.214832925	15	0.342374755	20	0.301016363	20	1.071417995	73	1.413348486	98	1.442386445	91	5.67E-06	2.143213041	up	4.62E-08	2.18920315	up	3.76E-07	2.096551793	up	1.61E-07	2.231786294	up	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08037|0|hsa:3174|HNF4G, NR2A2, NR2A3; hepatocyte nuclear factor 4, gamma; K08037 hepatocyte nuclear factor 4-gamma (A)"	Maturity onset diabetes of the young (ko04950)	[K]	Transcription	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Hepatocyte nuclear factor 4-gamma GN=HNF4G OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: hepatocyte nuclear factor 4-gamma isoform X1 [Oryctolagus cuniculus]
ENSG00000164751(PEX2)	--	14.9359731	490	14.35620375	506	19.12698873	507	18.26631871	591	16.82984184	580	13.23874465	508	0.933332046	0.238861383	normal	0.955118888	0.175000149	normal	0.971978595	-0.005432504	normal	0.598137803	0.138172016	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K06664|0|hsa:5828|PEX2, PAF1, PBD5A, PBD5B, PMP3, PMP35, PXMP3, RNF72, ZWS3; peroxisomal biogenesis factor 2; K06664 peroxin-2 (A)"	Peroxisome (ko04146)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Pex2 / Pex12 amino terminal region;; Zinc finger, C3HC4 type (RING finger)"	Peroxisome biogenesis factor 2 GN=PEX2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxisome biogenesis factor 2 [Galeopterus variegatus]
ENSG00000164754(RAD21)	--	68.01969334	4407	71.4960349	4380	66.22016187	4169	71.65060713	4475	66.22399383	4221	60.32037766	3971	0.992778744	-0.008738455	normal	0.991451106	-0.074746307	normal	0.991211134	-0.078461287	normal	0.837031477	-0.05418678	normal	--	--	Cellular Component: nuclear chromosome (GO:0000228);; Molecular Function: protein binding (GO:0005515);; 	K06670|0|pps:100988279|RAD21; RAD21 homolog (S. pombe); K06670 cohesin complex subunit SCC1 (A)	Cell cycle (ko04110)	[D]	"Cell cycle control, cell division, chromosome partitioning"	N terminus of Rad21 / Rec8 like protein;; Conserved region of Rad21 / Rec8 like protein;; ScpA/B protein	Double-strand-break repair protein rad21 homolog GN=RAD21 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: double-strand-break repair protein rad21 homolog isoformX1 [Canis lupus familiaris] 
ENSG00000164758(MED30)	--	6.808217	94	9.842077693	140	8.383960001	113	8.360266	118	6.5267096	94	7.362383	104	0.942574238	0.292941151	normal	0.623879507	-0.588311515	normal	0.96602548	-0.126268665	normal	0.772428007	-0.156827546	normal	--	--	--	"K15143|8.90527e-103|ptr:472911|MED30, THRAP6; mediator complex subunit 30; K15143 mediator of RNA polymerase II transcription subunit 30 (A)"	Thyroid hormone signaling pathway (ko04919)	--	--	Mediator complex subunit 30	Mediator of RNA polymerase II transcription subunit 30 GN=MED30 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 30 [Tupaia chinensis] 
ENSG00000164761(TNFRSF11B)	--	0.0719477	3	0.144693	6	0	0	0.071731	3	0.0692677	2	0.118439	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K05148|0|hsa:4982|TNFRSF11B, OCIF, OPG, TR1; tumor necrosis factor receptor superfamily, member 11b; K05148 tumor necrosis factor receptor superfamily member 11B (A)"	Cytokine-cytokine receptor interaction (ko04060);; Osteoclast differentiation (ko04380)	--	--	TNFR/NGFR cysteine-rich region;; Death domain	Tumor necrosis factor receptor superfamily member 11B (Precursor) GN=TNFRSF11B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: tumor necrosis factor receptor superfamily member 11B [Tupaia chinensis]
ENSG00000164764(SBSPON)	--	0.220858	12	0.218803	12	0.0726257	3	0.144703	8	0.141851	7	0.109023	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Somatomedin-B and thrombospondin type-1 domain-containing protein (Precursor) GN=SBSPON OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: somatomedin-B and thrombospondin type-1 domain-containing protein-like [Tupaia chinensis] 
ENSG00000164776(PHKG1)	--	4.1929189	189	4.39638679	201	4.6955984	216	4.8299272	219	4.252596	191	5.3335371	242	0.952634535	0.180349526	normal	0.962401361	-0.094321313	normal	0.956376338	0.154660796	normal	0.850413944	0.084776079	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K00871|0|hsa:5260|PHKG1, PHKG; phosphorylase kinase, gamma 1 (muscle) (EC:2.7.11.1 2.7.11.19 2.7.11.26); K00871 phosphorylase kinase gamma subunit [EC:2.7.11.19] (A)"	Calcium signaling pathway (ko04020);; Insulin signaling pathway (ko04910)	[G]	Carbohydrate transport and metabolism	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	"Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform GN=PHKG1 OS=Homo sapiens (Human) PE=2 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform 1 [Ceratotherium simum simum]"
ENSG00000164778(EN2)	--	0.813109	41	0.658287	34	0.437544	22	0.884369	45	0.707171	36	1.07226	55	0.980204988	0.099894995	normal	0.98192677	0.058506501	normal	0.142939535	1.25723581	normal	0.478938188	0.46607341	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09319|1.74139e-113|hsa:2020|EN2; engrailed homeobox 2; K09319 homeobox protein engrailed (A)	--	[R]	General function prediction only	Homeobox domain;; Engrailed homeobox C-terminal signature domain	Homeobox protein engrailed-2 GN=EN2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein engrailed-2 [Ochotona princeps]
ENSG00000164794(KCNV1)	--	3.42006	222	3.03073	212	2.719753	182	0.763803	50	1.156955	68	0.446541	30	9.44E-15	-2.147111169	down	4.53E-09	-1.640096758	down	2.22E-16	-2.549948571	down	6.82E-13	-2.079769106	down	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04934|0|pon:100172291|KCNV1; potassium channel, subfamily V, member 1; K04934 potassium channel subfamily V member 1 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily V member 1 GN=KCNV1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily V member 1 [Lipotes vexillifer]
ENSG00000164796(CSMD3)	--	0.060113801	12	0.017209446	2	0.086607771	11	0.366432459	74	0.397602852	73	0.228197731	47	2.15E-07	2.451553031	up	6.74E-14	4.390405456	up	0.003232038	1.94734349	up	4.95E-09	2.934803349	up	--	--	--	K17495|0|pps:100990418|CSMD3; CUB and Sushi multiple domains 3; K17495 CUB and sushi domain-containing protein (A)	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	CUB domain;; Sushi domain (SCR repeat);; CUB-like domain	CUB and sushi domain-containing protein 3 GN=CSMD3 OS=Homo sapiens (Human) PE=2 SV=3	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: CUB and sushi domain-containing protein 3-like isoform X1 [Mustela putorius furo] 
ENSG00000164808(SPIDR)	--	17.48203125	1128	14.5504163	1017	15.50189748	1007	13.75534169	944	15.76316908	974	14.60743586	1019	0.914282374	-0.287312084	normal	0.976314287	-0.083625478	normal	0.979737514	0.00878581	normal	0.582525764	-0.122967979	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4503);; Domain of unknown function (DUF4502)	DNA repair-scaffolding protein GN=SPIDR OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA0146 homolog [Ceratotherium simum simum]
ENSG00000164815(ORC5)	--	18.90614334	584	18.74364429	570	18.217846	554	19.96329606	622	21.071536	647	17.00282726	528	0.972121902	0.059961085	normal	0.959665094	0.160976165	normal	0.969931404	-0.077422976	normal	0.873092971	0.051610995	normal	--	--	Cellular Component: origin recognition complex (GO:0000808);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; 	"K02607|0|ptr:463636|ORC5, ORC5L; origin recognition complex, subunit 5; K02607 origin recognition complex subunit 5 (A)"	Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	Origin recognition complex (ORC) subunit 5 C-terminus;; AAA ATPase domain;; AAA domain	Origin recognition complex subunit 5 GN=ORC5 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: origin recognition complex subunit 5 [Dasypus novemcinctus]
ENSG00000164818(DNAAF5)	--	30.527677	1887	31.01373	1935	31.914064	2009	29.546069	1824	30.989255	1917	28.5770118	1780	0.984354629	-0.0797549	normal	0.985855708	-0.034882397	normal	0.973986696	-0.182745524	normal	0.65256774	-0.099955193	normal	--	--	--	--	--	--	--	HEAT repeats;; HEAT repeat;; Vacuolar 14 Fab1-binding region;; HEAT-like repeat;; non-SMC mitotic condensation complex subunit 1	"Dynein assembly factor 5, axonemal {ECO:0000303|PubMed:25232951} OS=Homo sapiens (Human) PE=1 SV=4"	S	Function unknown	HEAT repeat-containing protein 2 [Tupaia chinensis]
ENSG00000164823(OSGIN2)	--	31.9612	1716	38.66346	2081	34.86488	1829	28.157691	1473	26.28183	1450	40.8323	2151	0.949707905	-0.250881637	normal	0.202760313	-0.542175839	normal	0.964710544	0.225488911	normal	0.6515701	-0.169159868	normal	--	--	--	--	--	--	--	Pyridine nucleotide-disulphide oxidoreductase	Oxidative stress-induced growth inhibitor 2 GN=OSGIN2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: oxidative stress-induced growth inhibitor 2 [Equus przewalskii]
ENSG00000164825(DEFB1)	--	0	0	0	0	0	0	0	0	2.21359	6	1.25547	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Beta defensin	Beta-defensin 1 (Precursor) GN=DEFB1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: beta-defensin 1 [Equus caballus] 
ENSG00000164828(SUN1)	--	46.71093388	3369	42.53896482	3053	41.5905467	3027	29.29830229	2092	28.56098429	2060	28.58027724	2128	0.002938187	-0.717850105	normal	0.092392384	-0.588652378	normal	0.296757984	-0.516372638	normal	1.44E-05	-0.610624493	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	Mitochondrial RNA binding protein MRP;; Sad1 / UNC-like C-terminal	SUN domain-containing protein 1 GN=SUN1 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: SUN domain-containing protein 1 isoform X3 [Tupaia chinensis]
ENSG00000164830(OXR1)	--	6.8769631	460	7.905227432	472	7.532601667	484	8.91766333	543	9.60811094	532	7.007441414	408	0.945257204	0.207846572	normal	0.959294725	0.150757659	normal	0.924650897	-0.253864286	normal	0.896585106	0.044797902	normal	[L]	"Replication, recombination and repair"	--	--	--	[L]	"Replication, recombination and repair"	TLD;; LysM domain	Oxidation resistance protein 1 GN=OXR1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: oxidation resistance protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000164841(TMEM74)	--	0.863823	39	0.2966015	12	0.9418912	30	0.226827	10	0.41294	17	0.130902862	8	0.025459049	-1.84121392	normal	--	--	--	0.209873682	-1.735483672	normal	--	--	--	--	--	--	--	--	--	--	Neurensin	Transmembrane protein 74 GN=TMEM74 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 74 [Lipotes vexillifer]
ENSG00000164849(GPR146)	--	1.320833	31	1.06328	32	0.993171	27	0.67418459	20	0.26405875	7	0.846388	24	0.96133268	-0.624280445	normal	0.043131654	-1.996112053	normal	0.985362064	-0.168217336	normal	0.208246841	-0.840607961	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08431|0|hsa:115330|GPR146, PGR8; G protein-coupled receptor 146; K08431 G protein-coupled receptor 146 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 146 GN=GPR146 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 146 [Galeopterus variegatus]
ENSG00000164850(GPER1)	--	0.3414381	12	0.344177	16	0.0425123	0	0.170374313	7	0.428465884	19	0.26247728	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04246|0|pps:100967334|GPER1, GPER; G protein-coupled estrogen receptor 1; K04246 G protein-coupled receptor 30 (A)"	Estrogen signaling pathway (ko04915)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	G-protein coupled estrogen receptor 1 GN=GPER1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled estrogen receptor 1 [Galeopterus variegatus]
ENSG00000164853(UNCX)	--	0	0	0	0	0	0	0.0362339	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K09328|5.11404e-174|hsa:340260|UNCX, UNCX4.1; UNC homeobox; K09328 homeobox protein Unc-4 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein unc-4 homolog GN=UNCX OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox protein unc-4 homolog [Chrysochloris asiatica]
ENSG00000164855(TMEM184A)	--	5.231527393	668	6.464399585	794	5.41051	746	6.244924	783	6.72239	693	7.93434	1033	0.953310065	0.197911172	normal	0.947085893	-0.217266859	normal	0.501780772	0.460504586	normal	0.654011037	0.163973482	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Organic solute transporter Ostalpha	Transmembrane protein 184A GN=TMEM184A OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: transmembrane protein 184A isoform X1 [Ursus maritimus]
ENSG00000164867(NOS3)	--	0.068614312	5	0.0656406	6	0.158191	4	0	0	0.0322176	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[PE]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism	Molecular Function: nitric-oxide synthase activity (GO:0004517);; Biological Process: nitric oxide biosynthetic process (GO:0006809);; Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13242|0|ptr:463893|NOS3; nitric oxide synthase 3 (endothelial cell); K13242 nitric-oxide synthase, endothelial [EC:1.14.13.39] (A)"	Arginine and proline metabolism (ko00330);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; HIF-1 signaling pathway (ko04066);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; VEGF signaling pathway (ko04370);; Platelet activation (ko04611);; Estrogen signaling pathway (ko04915);; Oxytocin signaling pathway (ko04921)	[C]	Energy production and conversion	"Nitric oxide synthase, oxygenase domain;; FAD binding domain;; Flavodoxin;; Oxidoreductase NAD-binding domain"	"Nitric oxide synthase, endothelial GN=NOS3 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	nitric oxide synthase 3 [Oryctolagus cuniculus]
ENSG00000164877(MICALL2)	--	5.1881039	443	3.782946	380	4.520676	398	4.5070684	383	5.642026378	484	3.432919	314	0.931195614	-0.239898733	normal	0.866779343	0.326427561	normal	0.844372738	-0.348799562	normal	0.867818769	-0.069629972	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Protein of unknown function (DUF3585);; Calponin homology (CH) domain;; CAMSAP CH domain;; LIM domain	MICAL-like protein 2 GN=MICALL2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: MICAL-like protein 2 [Galeopterus variegatus]
ENSG00000164880(INTS1)	--	21.711752	3663	22.70301	3768	22.68795739	3970	19.111095	3290	20.69172	3478	19.75423	3479	0.982414158	-0.185688143	normal	0.987361959	-0.136910376	normal	0.981459313	-0.198676861	normal	0.361861285	-0.174846608	normal	--	--	--	"K13138|0|hsa:26173|INTS1, INT1, NET28; integrator complex subunit 1; K13138 integrator complex subunit 1 (A)"	--	[S]	Function unknown	Protein of unknown function (DUF3677)	Integrator complex subunit 1 GN=INTS1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: integrator complex subunit 1 [Galeopterus variegatus]
ENSG00000164885(CDK5)	--	17.23255	462	15.93248	417	17.99885	479	19.4902	534	19.35838	534	21.37092	537	0.95405108	0.177565033	normal	0.856065423	0.334292103	normal	0.959174104	0.156139188	normal	0.353497208	0.220098026	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02090|0|pps:100977790|CDK5; cyclin-dependent kinase 5; K02090 cyclin-dependent kinase 5 [EC:2.7.11.22] (A)	Axon guidance (ko04360);; Alzheimer's disease (ko05010);; Cocaine addiction (ko05030)	[UT]	"Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent-like kinase 5 GN=CDK5 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: cyclin-dependent kinase 5 isoform X1 [Myotis brandtii] 
ENSG00000164889(SLC4A2)	--	87.868336	6336	98.00390706	6982	89.989526	6564	109.059875	7091	116.75261	7517	113.849359	7525	0.992556203	0.131554333	normal	0.994136833	0.085072328	normal	0.989435482	0.18878425	normal	0.547443951	0.133699274	normal	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13855|0|hsa:6522|SLC4A2, AE2, BND3L, EPB3L1, HKB3, NBND3; solute carrier family 4 (anion exchanger), member 2; K13855 solute carrier family 4 (anion exchanger), member 2 (A)"	Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976)	[P]	Inorganic ion transport and metabolism	"HCO3- transporter family;; Band 3 cytoplasmic domain;; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2"	Anion exchange protein 2 GN=SLC4A2 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: anion exchange protein 2 [Galeopterus variegatus]
ENSG00000164896(FASTK)	--	30.97464262	931	28.3032056	882	30.18171054	927	32.093759	975	34.51010036	1017	32.69613646	1000	0.978501342	0.035731166	normal	0.961506726	0.183748967	normal	0.975039619	0.100908784	normal	0.654520284	0.105892454	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; 	K08290|0|pps:100978359|FASTK; Fas-activated serine/threonine kinase; K08290 Fas-activated serine/threonine kinase [EC:2.7.11.8] (A)	--	--	--	"FAST kinase-like protein, subdomain 2;; FAST kinase-like protein, subdomain 1;; RAP domain"	Fas-activated serine/threonine kinase GN=FASTK OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: fas-activated serine/threonine kinase isoform X1 [Oryctolagus cuniculus]
ENSG00000164897(TMUB1)	--	47.024312	997	39.38969164	838	44.03105786	985	44.07948857	940	43.28959453	926	38.83923709	840	0.973575388	-0.115581529	normal	0.971049699	0.122425161	normal	0.942672415	-0.237630319	normal	0.751448543	-0.080872793	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ubiquitin family	Transmembrane and ubiquitin-like domain-containing protein 1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane and ubiquitin-like domain containing 1 [Canis lupus familiaris]
ENSG00000164900(GBX1)	--	0.124985	2	0.0600256	1	0	0	0.122998	2	0.0603414	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09321|4.37145e-159|ptr:737612|GBX1; gastrulation brain homeobox 1; K09321 homeobox protein GBX (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein GBX-1 GN=GBX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: homeobox protein GBX-1 [Odobenus rosmarus divergens]
ENSG00000164902(PHAX)	--	10.63746572	927	10.21692578	907	10.65236941	931	12.78335707	1131	11.29271778	1000	9.781133635	867	0.935818848	0.255741184	normal	0.972524334	0.119209641	normal	0.973163253	-0.110853976	normal	0.693810868	0.094761148	normal	--	--	--	"K14291|0|ptr:462034|PHAX, RNUXA; phosphorylated adaptor for RNA export; K14291 phosphorylated adapter RNA export protein (A)"	RNA transport (ko03013)	[A]	RNA processing and modification	PHAX RNA-binding domain	Phosphorylated adapter RNA export protein GN=PHAX OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: phosphorylated adapter RNA export protein [Ceratotherium simum simum]
ENSG00000164904(ALDH7A1)	--	39.65659444	1520	38.31377929	1510	40.02798731	1590	35.49489215	1498	38.82177907	1545	43.80812315	1738	0.983276593	-0.051813205	normal	0.983809403	0.011620226	normal	0.980390269	0.120000676	normal	0.921405102	0.028760794	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K14085|0|hsa:501|ALDH7A1, ATQ1, EPD, PDE; aldehyde dehydrogenase 7 family, member A1 (EC:1.2.1.3 1.2.1.8 1.2.1.31); K14085 aldehyde dehydrogenase family 7 member A1 [EC:1.2.1.31 1.2.1.8 1.2.1.3] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Ascorbate and aldarate metabolism (ko00053);; Fatty acid degradation (ko00071);; Glycine, serine and threonine metabolism (ko00260);; Valine, leucine and isoleucine degradation (ko00280);; Lysine biosynthesis (ko00300);; Lysine degradation (ko00310);; Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tryptophan metabolism (ko00380);; beta-Alanine metabolism (ko00410);; Glycerolipid metabolism (ko00561);; Pyruvate metabolism (ko00620);; Biosynthesis of amino acids (ko01230)"	[C]	Energy production and conversion	Aldehyde dehydrogenase family	Alpha-aminoadipic semialdehyde dehydrogenase (Precursor) GN=ALDH7A1 OS=Homo sapiens (Human) PE=1 SV=5	C	Energy production and conversion	PREDICTED: alpha-aminoadipic semialdehyde dehydrogenase [Eptesicus fuscus]
ENSG00000164916(FOXK1)	--	9.612641	1786	9.898368691	1951	9.380643487	1961	9.830736755	1876	9.774785423	1778	9.884012262	2072	0.985599474	0.040061857	normal	0.977752486	-0.155258888	normal	0.985603562	0.071089686	normal	0.966740066	-0.013780957	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09404|0|hsa:221937|FOXK1, FOXK1L; forkhead box K1; K09404 forkhead box protein K (A)"	--	[K]	Transcription	Fork head domain;; FHA domain	Forkhead box protein K1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein K1 [Lipotes vexillifer]
ENSG00000164919(COX6C)	--	122.690842	892	129.137175	955	121.795802	897	157.1512822	1092	149.6075027	1000	147.1500767	1085	0.932077657	0.260618717	normal	0.978055207	0.044931271	normal	0.929134052	0.265815657	normal	0.340356447	0.190071945	normal	--	--	--	K02268|6.89811e-47|hsa:1345|COX6C; cytochrome c oxidase subunit VIc (EC:1.9.3.1); K02268 cytochrome c oxidase subunit 6c (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	Cytochrome c oxidase subunit VIc	Cytochrome c oxidase subunit 6C GN=COX6C OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: cytochrome c oxidase subunit 6C-like [Elephantulus edwardii]
ENSG00000164920(OSR2)	--	1.269186398	35	0.661024087	18	1.615142546	43	1.358989168	41	1.1709126	35	1.504699135	45	0.979906777	0.189735885	normal	0.88092133	0.883846691	normal	0.980111388	0.055392449	normal	0.682276928	0.313955105	normal	[R]	General function prediction only	--	K09215|0|ocu:100339888|OSR2; odd-skipped related transciption factor 2; K09215 odd-skipped (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger"	Protein odd-skipped-related 2 GN=OSR2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: protein odd-skipped-related 2 [Equus przewalskii]
ENSG00000164924(YWHAZ)	--	323.3672406	13111	333.4814716	13676	320.2050679	12965	481.0513408	18605	413.2229777	16530	354.1919658	14263	0.765645464	0.474033559	normal	0.989748541	0.251988462	normal	0.995846519	0.129349424	normal	0.128746887	0.291370747	normal	[T]	Signal transduction mechanisms	--	"K16197|1.12967e-170|umr:103661509|YWHAZ; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta; K16197 14-3-3 protein beta/theta/zeta (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; Hippo signaling pathway (ko04390);; Hepatitis B (ko05161);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein	14-3-3 protein zeta/delta GN=YWHAZ OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"Chain A, 14-3-3 Protein Zeta In Complex With Thr758 Phosphorylated Integrin Beta2 Peptide "
ENSG00000164929(BAALC)	--	0.086911433	4	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: cytoplasm (GO:0005737);; 	--	--	--	--	BAALC N-terminus	Brain and acute leukemia cytoplasmic protein GN=BAALC OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: brain and acute leukemia cytoplasmic protein [Odobenus rosmarus divergens]
ENSG00000164930(FZD6)	--	23.71806418	1379	27.15666992	1577	22.97881354	1310	19.05579161	1116	22.28032193	1287	23.94436608	1388	0.866678702	-0.335700997	normal	0.902402026	-0.314262916	normal	0.981056049	0.075065118	normal	0.316434747	-0.191059393	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	"K02376|0|hsa:8323|FZD6, FZ-6, FZ6, HFZ6, NDNC10; frizzled class receptor 6; K02376 frizzled 6 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-6 (Precursor) GN=FZD6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: frizzled-6 [Galeopterus variegatus]
ENSG00000164932(CTHRC1)	--	2.810402363	52	1.553790717	29	2.820956449	53	0.796671223	10	1.302633039	23	0.536439828	11	0.000110981	-2.242657323	down	0.979981864	-0.336119878	normal	0.000235593	-2.130911242	down	0.003118066	-1.626600744	down	--	--	--	--	--	--	--	Collagen triple helix repeat (20 copies)	Collagen triple helix repeat-containing protein 1 (Precursor) GN=CTHRC1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: collagen triple helix repeat-containing protein 1 [Ovis aries]
ENSG00000164933(SLC25A32)	--	12.9837	547	12.8407	541	13.1379	545	14.2548	605	13.3411	562	12.5136	528	0.966958181	0.114256816	normal	0.971612158	0.033423311	normal	0.971276925	-0.0538579	normal	0.926716713	0.032161073	normal	--	--	--	"K15115|0|pps:100981455|SLC25A32; solute carrier family 25 (mitochondrial folate carrier), member 32; K15115 solute carrier family 25 (mitochondrial folate transporter), member 32 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial folate transporter/carrier GN=SLC25A32 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: mitochondrial folate transporter/carrier isoform X2 [Equus przewalskii]
ENSG00000164934(DCAF13)	--	36.92573809	1217	38.920537	1276	43.19322686	1416	35.94267971	1207	35.597826	1178	34.2369863	1156	0.981115036	-0.042681648	normal	0.97408563	-0.13654686	normal	0.909737889	-0.300615335	normal	0.412464527	-0.163737501	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11806|0|hsa:25879|DCAF13, GM83, WDSOF1; DDB1 and CUL4 associated factor 13; K11806 WD repeat and SOF domain-containing protein 1 (A)"	--	[A]	RNA processing and modification	"Sof1-like domain;; WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	DDB1- and CUL4-associated factor 13 GN=DCAF13 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	"PREDICTED: LOW QUALITY PROTEIN: DDB1 and CUL4 associated factor 13, partial [Panthera tigris altaica]"
ENSG00000164938(TP53INP1)	--	4.86275	377	7.71426	597	5.74123	436	7.71252	602	8.58265	664	12.41307	962	0.051231294	0.642278188	normal	0.965196347	0.131709292	normal	2.52E-08	1.130708922	up	0.14424697	0.639978471	normal	--	--	--	K15310|1.32537e-161|pps:100983445|TP53INP1; tumor protein p53 inducible nuclear protein 1; K15310 tumor protein p53-inducible nuclear protein 1 (A)	HTLV-I infection (ko05166)	--	--	DOR family	Tumor protein p53-inducible nuclear protein 1 GN=TP53INP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: tumor protein p53-inducible nuclear protein 1 isoform 1 [Dasypus novemcinctus]
ENSG00000164941(INTS8)	--	19.83918581	979	20.985461	926	20.1904	961	23.13796034	999	21.21770265	978	20.22636795	814	0.979419238	-0.001653876	normal	0.977239238	0.057304646	normal	0.937288682	-0.247375584	normal	0.827154693	-0.059982951	normal	--	--	--	"K13145|0|hsa:55656|INTS8, C8orf52, INT8; integrator complex subunit 8; K13145 integrator complex subunit 8 (A)"	--	--	--	--	Integrator complex subunit 8 GN=INTS8 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: integrator complex subunit 8 [Sus scrofa]
ENSG00000164944(KIAA1429)	--	15.45938715	1815	15.52626843	1873	14.98146521	1742	15.15734051	1779	15.76066854	1816	14.52217197	1697	0.984855938	-0.059684266	normal	0.984544834	-0.065959166	normal	0.984849679	-0.046009032	normal	0.818126787	-0.058551313	normal	--	--	--	--	--	[AT]	RNA processing and modification;; Signal transduction mechanisms	--	Protein virilizer homolog GN=KIAA1429 OS=Homo sapiens (Human) PE=1 SV=2	AT	RNA processing and modification;; Signal transduction mechanisms	PREDICTED: protein virilizer homolog [Odobenus rosmarus divergens]
ENSG00000164949(GEM)	--	3.128237521	122	5.620559045	217	2.665721702	103	3.760368958	148	4.379936914	169	6.132341937	239	0.94612851	0.245078215	normal	0.85272399	-0.379096097	normal	1.97E-05	1.194232638	up	0.67040182	0.310344944	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07846|0|nle:100600274|GEM; GTP binding protein overexpressed in skeletal muscle; K07846 GTP binding protein overexpressed in skeletal muscle (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein;; Ferrous iron transport protein B	GTP-binding protein GEM GN=GEM OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GTP-binding protein GEM isoform X2 [Lipotes vexillifer]
ENSG00000164951(PDP1)	--	16.54449268	956	13.69034043	882	12.35889633	781	14.01287004	895	12.31900543	738	15.12799058	921	0.971757692	-0.125746273	normal	0.91661914	-0.278062392	normal	0.945018043	0.229178087	normal	0.836981988	-0.057713249	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K01102|0|hsa:54704|PDP1, PDH, PDP, PDPC, PPM2C; pyruvate dehyrogenase phosphatase catalytic subunit 1 (EC:3.1.3.43); K01102 pyruvate dehydrogenase phosphatase [EC:3.1.3.43] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C	"[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial (Precursor) GN=PDP1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000164953(TMEM67)	--	8.077782822	314	5.852911993	336	7.375449108	341	5.338962034	269	7.047449544	307	5.941052286	280	0.927015453	-0.252653313	normal	0.955864747	-0.150938116	normal	0.904472614	-0.291208716	normal	0.415123121	-0.232211651	normal	--	--	Biological Process: negative regulation of centrosome duplication (GO:0010826);; Cellular Component: TCTN-B9D complex (GO:0036038);; Biological Process: cilium morphogenesis (GO:0060271);; 	--	--	[S]	Function unknown	Meckelin (Transmembrane protein 67)	Meckelin GN=TMEM67 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: meckelin [Tupaia chinensis]
ENSG00000164961(WASHC5)	--	29.08529321	2260	32.305631	2465	29.35232442	2228	28.274711	2189	27.77973397	2150	29.04209699	2261	0.986327565	-0.076830005	normal	0.969700618	-0.218533854	normal	0.987873739	0.012911618	normal	0.667057014	-0.096393519	normal	--	--	Cellular Component: WASH complex (GO:0071203);; 	K18464|0|pps:100975560|KIAA0196 ortholog; K18464 WASH complex subunit strumpellin (A)	--	[S]	Function unknown	Hereditary spastic paraplegia protein strumpellin	WASH complex subunit strumpellin GN=KIAA0196 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: WASH complex subunit strumpellin isoform X1 [Vicugna pacos]
ENSG00000164967(RPP25L)	--	24.86859	347	24.82561	362	30.96776	446	29.02764	404	25.02785	343	24.12966	339	0.94936385	0.187816133	normal	0.963341542	-0.098783653	normal	0.743703474	-0.402479456	normal	0.731192624	-0.110224059	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K14525|1.12784e-76|ggo:101126918|RPP25L; ribonuclease P protein subunit p25-like protein isoform 1; K14525 ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5] (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[S]	Function unknown	Alba	Ribonuclease P protein subunit p25-like protein GN=RPP25L OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ribonuclease P protein subunit p25-like protein [Sorex araneus]
ENSG00000164970(FAM219A)	--	15.871415	1049	13.155197	888	15.760506	987	15.35948705	909	15.199684	823	11.212064	707	0.9441767	-0.237121241	normal	0.969555284	-0.130862235	normal	0.38643565	-0.488742276	normal	0.119789051	-0.283519678	normal	--	--	--	--	--	--	--	Protein family FAM219A	Protein FAM219A GN=FAM219A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM219A isoform X1 [Chrysochloris asiatica]
ENSG00000164972(C9orf24)	--	0.334580523	2	0	0	0.602757511	2	0.3517244	6	0.290905612	4	0.1601835	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18634|0|pps:100972923|chromosome unknown open reading frame, human C9orf24; K18634 spermatid-specific manchette-related protein 1 (A)"	--	--	--	Spermatid-specific manchette-related protein 1	Spermatid-specific manchette-related protein 1 GN=SMRP1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: spermatid-specific manchette-related protein 1 isoform X2 [Felis catus]
ENSG00000164975(SNAPC3)	--	12.014371	786	11.783359	783	12.93927724	744	10.915893	675	9.087726	556	11.172568	674	0.93180095	-0.249946202	normal	0.32365071	-0.514169286	normal	0.964375343	-0.15052387	normal	0.115399305	-0.301349717	normal	--	--	--	"K15210|0|pps:100980089|SNAPC3; small nuclear RNA activating complex, polypeptide 3, 50kDa; K15210 snRNA-activating protein complex subunit 3 (A)"	--	[K]	Transcription	snRNA-activating protein of 50kDa MW C terminal	snRNA-activating protein complex subunit 3 GN=SNAPC3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: snRNA-activating protein complex subunit 3 [Galeopterus variegatus]
ENSG00000164976(KIAA1161)	--	4.60454	547	2.970414	356	4.340409	517	5.328908	630	6.109646	718	4.552175	540	0.957171474	0.172526924	normal	1.10E-05	0.987667769	normal	0.971092435	0.054348124	normal	0.177614098	0.389783822	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 31	Uncharacterized family 31 glucosidase KIAA1161 GN=KIAA1161 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: uncharacterized family 31 glucosidase KIAA1161 isoform X1 [Canis lupus familiaris] 
ENSG00000164978(NUDT2)	--	13.07059312	190	11.294777	165	10.96857824	163	14.77319408	217	12.79620691	181	12.25345644	183	0.956185129	0.159654716	normal	0.961524105	0.11112446	normal	0.957795864	0.157302197	normal	0.731740104	0.143696232	normal	[LR]	"Replication, recombination and repair;; General function prediction only"	Molecular Function: hydrolase activity (GO:0016787);; 	K01518|7.42748e-105|ptr:465056|NUDT2; nudix (nucleoside diphosphate linked moiety X)-type motif 2; K01518 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[T]	Signal transduction mechanisms	NUDIX domain	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] GN=NUDT2 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: bis(5'-nucleosyl)-tetraphosphatase [asymmetrical] isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000164983(TMEM65)	--	7.941865995	930	8.582771154	1011	8.1076744	935	9.848885	1167	8.672204873	1017	8.820537409	1036	0.906833151	0.296232033	normal	0.97919013	-0.012870681	normal	0.970901493	0.139479889	normal	0.5129292	0.141316275	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF2453)	Transmembrane protein 65 GN=TMEM65 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 65 [Odobenus rosmarus divergens]
ENSG00000164985(PSIP1)	--	49.5088749	2953	44.264704	2747	45.40614245	2799	32.0260825	1997	37.544416	2101	29.33823	1864	0.06746068	-0.5948003	normal	0.766078047	-0.407949654	normal	0.067992307	-0.594404738	normal	0.00020483	-0.532860048	normal	--	--	--	--	--	[K]	Transcription	Lens epithelium-derived growth factor (LEDGF);; PWWP domain	PC4 and SFRS1-interacting protein GN=PSIP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: PC4 and SFRS1-interacting protein-like isoform X2 [Physeter catodon] 
ENSG00000164989(CCDC171)	--	0.742050829	86	0.943130135	87	1.117883434	103	0.325282436	38	0.318723181	36	0.582547154	69	0.025036955	-1.176662641	normal	0.010173003	-1.259326126	normal	0.77450098	-0.575868515	normal	0.017494075	-0.967715661	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 171 GN=CCDC171 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 171 isoform 2 [Ceratotherium simum simum]
ENSG00000165006(UBAP1)	--	21.0960713	1042	19.2438382	982	19.8747317	982	25.32025144	1282	26.4548624	1312	27.89727257	1390	0.931697541	0.267852152	normal	0.747079418	0.396016963	normal	0.36425628	0.492358104	normal	0.015724671	0.385386534	normal	--	--	--	--	--	--	--	UBA/TS-N domain	Ubiquitin-associated protein 1 GN=UBAP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-associated protein 1 isoform X2 [Myotis davidii]
ENSG00000165023(DIRAS2)	--	0.013232285	1	0.188360015	1	0	0	0	0	0.012840581	0	0.039462791	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07841|8.55421e-133|ptr:472981|DIRAS2; DIRAS family, GTP-binding RAS-like 2; K07841 DIRAS family, GTP-binding Ras-like 2 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein	GTP-binding protein Di-Ras2 (Precursor) GN=DIRAS2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GTP-binding protein Di-Ras2 [Oryctolagus cuniculus] 
ENSG00000165025(SYK)	--	0.038793099	4	0.190971679	20	0.14114592	14	0.124943489	13	0.084703187	8	0.113084691	12	--	--	--	0.913015249	-1.196267544	normal	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05855|0|pps:100978194|SYK; spleen tyrosine kinase; K05855 spleen tyrosine kinase [EC:2.7.10.2] (A)	NF-kappa B signaling pathway (ko04064);; PI3K-Akt signaling pathway (ko04151);; Osteoclast differentiation (ko04380);; Platelet activation (ko04611);; Natural killer cell mediated cytotoxicity (ko04650);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Tuberculosis (ko05152);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	--	--	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain	Tyrosine-protein kinase SYK GN=SYK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase SYK [Galeopterus variegatus]
ENSG00000165028(NIPSNAP3B)	--	1.628305574	148	1.338549273	109	1.548432554	139	1.087436648	74	1.063277508	88	1.184953911	85	0.008342545	-1.015612348	down	0.934373436	-0.325148102	normal	0.342821287	-0.707893683	normal	0.048800072	-0.701510039	normal	--	--	--	--	--	[S]	Function unknown	NIPSNAP	Protein NipSnap homolog 3B GN=NIPSNAP3B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein NipSnap homolog 3A-like isoform X1 [Mustela putorius furo] 
ENSG00000165029(ABCA1)	--	3.5662745	722	3.129996	635	2.608934	523	9.6935	1959	10.810863	2172	4.337086	875	1.54E-14	1.407323378	up	0	1.750374327	up	0.004433931	0.732525408	normal	0.037141873	1.389565368	normal	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05641|0|hsa:19|ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD; ATP-binding cassette, sub-family A (ABC1), member 1; K05641 ATP-binding cassette, subfamily A (ABC1), member 1 (A)"	ABC transporters (ko02010);; Fat digestion and absorption (ko04975)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC-2 family transporter protein;; ABC transporter;; AAA domain	ATP-binding cassette sub-family A member 1 GN=ABCA1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family A member 1 isoform X2 [Oryctolagus cuniculus]
ENSG00000165030(NFIL3)	--	11.77334893	476	13.16328323	525	9.027682328	359	5.894819972	239	5.826457147	235	11.95876986	485	1.53E-05	-1.020039433	down	1.70E-07	-1.175879341	down	0.682289658	0.424166644	normal	0.350283491	-0.523617615	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: circadian rhythm (GO:0007623);; "	"K09059|0|ptr:742792|NFIL3; nuclear factor, interleukin 3 regulated; K09059 nuclear factor, interleukin 3 regulated (A)"	--	[K]	Transcription	Vertebrate interleukin-3 regulated transcription factor;; Basic region leucine zipper;; bZIP transcription factor	Nuclear factor interleukin-3-regulated protein GN=NFIL3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear factor interleukin-3-regulated protein [Orycteropus afer afer]
ENSG00000165046(LETM2)	--	1.050505732	38	1.816654556	21	1.50841297	64	2.882038443	98	1.125202529	54	1.893002473	74	0.003235906	1.302045825	up	0.134179237	1.281679491	normal	0.968368349	0.196833179	normal	0.17643286	0.856888345	normal	--	--	--	--	--	[S]	Function unknown	LETM1-like protein	"LETM1 domain-containing protein LETM2, mitochondrial (Precursor) GN=LETM2 OS=Homo sapiens (Human) PE=2 SV=2"	S	Function unknown	"PREDICTED: LETM1 domain-containing protein LETM2, mitochondrial [Ursus maritimus] "
ENSG00000165055(METTL2B)	--	18.3587888	1039	18.70411434	1055	18.50278233	1112	18.1350412	1048	17.36995984	968	16.93116031	916	0.979919163	-0.018362165	normal	0.969965843	-0.14537297	normal	0.913824169	-0.287597072	normal	0.482232272	-0.150388053	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family	Methyltransferase-like protein 2B GN=METTL2B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: methyltransferase-like protein 2B [Galeopterus variegatus]
ENSG00000165060(FXN)	--	11.11573109	201	11.58052865	204	11.64071823	211	13.78285285	261	12.62827432	256	12.77956963	220	0.874363091	0.343711021	normal	0.903740922	0.304131807	normal	0.965968561	0.051606831	normal	0.474146437	0.237142094	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ferric iron binding (GO:0008199);; Biological Process: iron-sulfur cluster assembly (GO:0016226);; 	--	--	[P]	Inorganic ion transport and metabolism	Frataxin-like domain	Frataxin mature form (Precursor) GN=FXN OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	"PREDICTED: frataxin, mitochondrial [Orycteropus afer afer]"
ENSG00000165061(ZMAT4)	--	2.929304954	74	1.863831243	57	2.987065893	95	0.965334242	32	1.783609279	58	0.92662888	33	0.046005952	-1.201254858	normal	0.975935115	0.003570515	normal	0.000367809	-1.491647333	down	0.048881565	-0.897716651	normal	--	--	--	--	--	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; U1 zinc finger;; C2H2-type zinc finger	Zinc finger matrin-type protein 4 GN=ZMAT4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger matrin-type protein 4 isoform X2 [Oryctolagus cuniculus]
ENSG00000165066(NKX6-3)	--	0	0	0.103546455	4	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09351|9.76316e-178|ptr:736590|NKX6-3; NK6 homeobox 3; K09351 homeobox protein Nkx-6.3 (A)	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-6.3 GN=NKX6-3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox protein Nkx-6.3 [Eptesicus fuscus]
ENSG00000165071(TMEM71)	--	0.03481539	1	0	0	0.09660564	2	0.069099699	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMEM71 protein family	Transmembrane protein 71 GN=TMEM71 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 71 isoform X1 [Mustela putorius furo] 
ENSG00000165072(MAMDC2)	--	0.0470803	3	0.0623908	4	0.0155185	0	0.0936559	6	0.243632	15	0.186823	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	--	--	MAM domain	MAM domain-containing protein 2 (Precursor) GN=MAMDC2 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: MAM domain-containing protein 2 [Oryctolagus cuniculus]
ENSG00000165076(PRSS37)	--	0	0	0	0	0	0	0	0	0	0	0.105124	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin	Probable inactive serine protease 37 (Precursor) GN=PRSS37 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable inactive serine protease 37 isoform X1 [Galeopterus variegatus]
ENSG00000165078(CPA6)	--	0	0	0.0308376	1	0	0	0	0	0.21007	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: carboxypeptidase activity (GO:0004180);; Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	"K08782|0|hsa:57094|CPA6, CPAH, ETL5, FEB11; carboxypeptidase A6 (EC:3.4.17.1); K08782 carboxypeptidase A6 [EC:3.4.17.1] (A)"	--	[S]	Function unknown	Zinc carboxypeptidase;; Carboxypeptidase activation peptide	Carboxypeptidase A6 (Precursor) GN=CPA6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: carboxypeptidase A6 [Loxodonta africana]
ENSG00000165084(C8orf34)	--	0.103912967	6	0	0	0.063440629	3	0.069050604	3	0.149711284	5	0.019423389	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C8orf34 GN=C8orf34 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C8orf34 homolog [Odobenus rosmarus divergens]
ENSG00000165091(TMC1)	--	0	0	0	0	0	0	0.029732206	2	0	0	0.0149721	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 1 GN=TMC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane channel-like 1 isoform X1 [Sus scrofa] 
ENSG00000165092(ALDH1A1)	--	1965.138659	66630	2013.078921	69736	2032.402232	68403	2952.227748	101120	3226.226359	109126	2628.390218	89792	0.599986397	0.570981549	normal	0.329468968	0.624581885	normal	0.984525728	0.384228436	normal	0.011834257	0.529681471	normal	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07249|0|ptr:464529|ALDH1A1; aldehyde dehydrogenase 1 family, member A1 (EC:1.2.1.36); K07249 retinal dehydrogenase [EC:1.2.1.36] (A)"	Retinol metabolism (ko00830)	[C]	Energy production and conversion	Aldehyde dehydrogenase family;; Acyl-CoA reductase (LuxC)	Retinal dehydrogenase 1 GN=ALDH1A1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: retinal dehydrogenase 1-like [Tupaia chinensis]
ENSG00000165097(KDM1B)	--	7.627070122	571	4.852204271	392	7.051847339	542	5.451392546	421	4.352733749	352	3.654978263	296	0.512673147	-0.469026555	normal	0.951489863	-0.17598788	normal	0.00036797	-0.877622229	normal	0.080928635	-0.515476808	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: tRNA processing (GO:0008033);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; Molecular Function: FAD binding (GO:0071949);; 	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Flavin containing amine oxidoreductase;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; Thi4 family;; FAD-NAD(P)-binding;; Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase;; HI0933-like protein;; SWIRM domain;; FAD binding domain	Lysine-specific histone demethylase 1B GN=KDM1B OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: lysine-specific histone demethylase 1B isoform X1 [Galeopterus variegatus] 
ENSG00000165102(HGSNAT)	--	18.09375957	1525	17.52355453	1485	17.35839244	1401	27.0067612	2142	28.66132253	2274	29.08909677	2446	0.530761729	0.458925206	normal	0.080560241	0.592851448	normal	0.0003252	0.795018282	normal	1.20E-05	0.616619618	normal	[S]	Function unknown	--	"K10532|0|hsa:138050|HGSNAT, HGNAT, MPS3C, TMEM76; heparan-alpha-glucosaminide N-acetyltransferase (EC:2.3.1.78); K10532 heparan-alpha-glucosaminide N-acetyltransferase [EC:2.3.1.78] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	[S]	Function unknown	Protein of unknown function (DUF1624)	Heparan-alpha-glucosaminide N-acetyltransferase GN=HGSNAT OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: heparan-alpha-glucosaminide N-acetyltransferase [Odobenus rosmarus divergens]
ENSG00000165105(RASEF)	--	9.040813	633	13.2712781	929	10.6501028	732	14.52180083	1053	17.45940938	1299	20.659001	1597	0.007403141	0.702061516	normal	0.516835664	0.461586234	normal	8.31E-09	1.115557821	up	0.018283273	0.763493877	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K17199|0|hsa:158158|RASEF, RAB45; RAS and EF-hand domain containing; K17199 Ras and EF-hand domain-containing protein (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; EF hand;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF-hand domain pair;; 50S ribosome-binding GTPase	Ras and EF-hand domain-containing protein GN=RASEF OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras and EF-hand domain-containing protein-like [Ceratotherium simum simum]
ENSG00000165113(GKAP1)	--	5.04742	173	6.594643589	230	6.709901796	217	5.75277221	189	4.847610502	162	4.88019781	160	0.963835848	0.095966389	normal	0.578797225	-0.522947201	normal	0.767795197	-0.444294413	normal	0.375239879	-0.300610007	normal	--	--	--	--	--	--	--	--	G kinase-anchoring protein 1 GN=GKAP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G kinase-anchoring protein 1 [Pteropus alecto]
ENSG00000165115(KIF27)	--	3.3758891	216	4.00675483	234	3.647031909	236	2.313943142	190	2.690274698	200	3.181814054	253	0.945190031	-0.214237884	normal	0.93302669	-0.246211886	normal	0.96364709	0.091492745	normal	0.778228833	-0.113656887	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10395|0|nle:100600385|KIF27; kinesin family member 27; K10395 kinesin family member 4/21/27 (A)	--	--	--	Kinesin motor domain	Kinesin-like protein KIF27 GN=KIF27 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: kinesin family member 27 isoform X1 [Equus caballus]
ENSG00000165118(C9orf64)	--	18.52584702	772	15.79909383	679	16.6344395	715	14.718965	648	17.92233301	759	14.87049024	648	0.909264034	-0.282823955	normal	0.965885965	0.138968898	normal	0.963942941	-0.149907666	normal	0.713277133	-0.096997762	normal	--	--	--	--	--	[H]	Coenzyme transport and metabolism	Protein of unknown function (DUF2419)	UPF0553 protein C9orf64 GN=C9orf64 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: UPF0553 protein C9orf64 homolog [Tupaia chinensis] 
ENSG00000165119(HNRNPK)	--	271.8156306	10663	301.3185139	11923	285.1975909	10976	341.8955461	13571	325.2905685	12606	294.9946478	11511	0.973566655	0.317040802	normal	0.996461824	0.058929456	normal	0.996315275	0.06036122	normal	0.525184117	0.145519081	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K12886|0|umr:103667628|HNRNPK; heterogeneous nuclear ribonucleoprotein K; K12886 heterogeneous nuclear ribonucleoprotein K (A)	Spliceosome (ko03040);; Herpes simplex infection (ko05168);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206)	[AR]	RNA processing and modification;; General function prediction only	KH domain;; KH domain;; ROKNT (NUC014) domain;; KH domain;; KH domain	Heterogeneous nuclear ribonucleoprotein K GN=HNRNPK OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein K isoform X1 [Ochotona princeps] 
ENSG00000165124(SVEP1)	--	3.597333651	863	3.164901322	664	3.213804707	753	0.294952876	73	0.469759437	116	1.078924798	268	0	-3.566395377	down	0	-2.52291801	down	1.25E-13	-1.493453213	down	2.77E-15	-2.336193632	down	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K17495|0|hsa:79987|SVEP1, C9orf13, CCP22, POLYDOM, SEL-OB, SELOB; sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1; K17495 CUB and sushi domain-containing protein (A)"	--	[T]	Signal transduction mechanisms	Sushi domain (SCR repeat);; EGF-like domain;; GCC2 and GCC3;; HYR domain;; von Willebrand factor type A domain;; Pentaxin family;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain;; von Willebrand factor type A domain;; Calcium-binding EGF domain;; EGF domain;; Human growth factor-like EGF	"Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (Precursor) GN=SVEP1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 [Equus caballus]"
ENSG00000165125(TRPV6)	--	0.01708827	1	0.022735774	1	0	0	0	0	0.022558331	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04975|0|mcf:102117126|TRPV6; transient receptor potential cation channel, subfamily V, member 6; K04975 transient receptor potential cation channel subfamily V member 6 (A)"	Salivary secretion (ko04970);; Mineral absorption (ko04978)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ion transport protein	Transient receptor potential cation channel subfamily V member 6 GN=TRPV6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	Transient receptor potential cation channel subfamily V member 6 [Tupaia chinensis]
ENSG00000165138(ANKS6)	--	9.6610538	1336	8.547638985	1184	8.997887436	1279	8.900857261	1285	9.182452127	1336	8.865769729	1263	0.979968926	-0.086882019	normal	0.972232391	0.15264075	normal	0.982082916	-0.026421629	normal	0.976817231	0.010762877	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Ankyrin repeat and SAM domain-containing protein 6 GN=ANKS6 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ankyrin repeat and SAM domain-containing protein 6 isoform X3 [Bos taurus] 
ENSG00000165152(TMEM246)	--	15.4491321	956	15.71413078	952	14.4104701	897	14.94486382	953	14.28488568	895	16.70350781	1039	0.978537596	-0.03530983	normal	0.973050519	-0.110319668	normal	0.956823028	0.203405424	normal	0.953328303	0.020498379	normal	--	--	--	--	--	--	--	--	Transmembrane protein 246 GN=TMEM246 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 246 [Camelus ferus] 
ENSG00000165156(ZHX1)	--	24.67822892	1032	26.4679778	993	23.51930005	922	26.36356108	1194	25.74048733	1131	24.20277834	1014	0.965510771	0.179279306	normal	0.967201814	0.16606964	normal	0.972104305	0.128726155	normal	0.444530341	0.158345771	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	"Homeobox domain;; Homeodomain leucine-zipper encoding, Homez;; Homeobox KN domain"	Zinc fingers and homeoboxes protein 1 GN=ZHX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: zinc fingers and homeoboxes protein 1, isoform 2-like isoform 1 [Ceratotherium simum simum]"
ENSG00000165164(CFAP47)	--	0.01687111	1	0.0337775	2	0.010046107	0	0.045196771	3	0.130800469	13	0.090431294	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Calponin homology (CH) domain	Uncharacterized protein CXorf22 GN=CXorf22 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	"PREDICTED: uncharacterized protein LOC101675622, partial [Mustela putorius furo] "
ENSG00000165168(CYBB)	--	0.137755	10	0.0410458	3	0.0687483	4	0.109301	8	0.12057	8	0.0959527	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K08008|0|ptr:465566|cytochrome b-245 heavy chain; K08008 NADPH oxidase (A)	HIF-1 signaling pathway (ko04066);; Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Leukocyte transendothelial migration (ko04670)	[PQ]	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Ferric reductase NAD binding domain;; FAD-binding domain;; Ferric reductase like transmembrane component;; Oxidoreductase FAD-binding domain	Cytochrome b-245 heavy chain GN=CYBB OS=Homo sapiens (Human) PE=1 SV=2	PQ	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome b-245 heavy chain-like [Myotis davidii] 
ENSG00000165169(DYNLT3)	--	20.5122114	603	22.435488	647	20.217255	582	25.4177835	746	23.7749138	696	23.0707238	679	0.91406328	0.275553187	normal	0.971254129	0.083706373	normal	0.946178144	0.21358669	normal	0.393579068	0.189698209	normal	--	--	--	"K10420|2.50907e-73|ptr:738114|DYNLT3; dynein, light chain, Tctex-type 3; K10420 dynein light chain Tctex-type 1 (A)"	--	[N]	Cell motility	Tctex-1 family	Dynein light chain Tctex-type 3 GN=DYNLT3 OS=Homo sapiens (Human) PE=1 SV=1	N	Cell motility	PREDICTED: dynein light chain Tctex-type 3 [Oryctolagus cuniculus]
ENSG00000165171(WBSCR27)	--	9.930514	361	5.556939	249	8.73037	322	7.613235	281	6.571058	227	5.656809	236	0.785986277	-0.390372117	normal	0.955128724	-0.15390061	normal	0.666100436	-0.454064021	normal	0.202145482	-0.346656074	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family	Williams-Beuren syndrome chromosomal region 27 protein GN=WBSCR27 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: Williams-Beuren syndrome chromosomal region 27 protein [Eptesicus fuscus]
ENSG00000165175(MID1IP1)	--	29.80785445	1230	28.586299	1283	24.65104154	1127	30.30061636	1410	29.82809	1358	40.854436	1907	0.971030243	0.1660108	normal	0.981054126	0.060466472	normal	0.001363268	0.749743746	normal	0.222832775	0.340521445	normal	--	--	--	--	--	--	--	Thyroid hormone-inducible hepatic protein Spot 14	Mid1-interacting protein 1 GN=MID1IP1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: mid1-interacting protein 1 [Felis catus]
ENSG00000165181(C9orf84)	--	0.023820346	2	0.011600139	1	0.012117257	0	0.011854973	1	0.051559984	2	0.041541689	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf84 GN=C9orf84 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf84 homolog [Ceratotherium simum simum]
ENSG00000165182(CXorf58)	--	0.11469	3	0.11307	3	0.11266	2	0.0751034	2	0.0367121	0	0.150896	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative uncharacterized protein CXorf58 GN=CXorf58 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: putative uncharacterized protein CXorf58 homolog [Galeopterus variegatus]
ENSG00000165185(KIAA1958)	--	3.714355917	684	4.238797364	774	4.105433161	739	3.210732937	604	3.25060961	624	2.314065326	453	0.94762419	-0.209778161	normal	0.859938921	-0.33149118	normal	0.008895349	-0.712473558	normal	0.024587694	-0.408139846	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF3504)	Uncharacterized protein KIAA1958 GN=KIAA1958 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA1958 homolog isoform X2 [Galeopterus variegatus]
ENSG00000165186(PTCHD1)	--	0.004406594	1	0	0	0	0	0	0	0.008529802	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Patched family;; Sterol-sensing domain of SREBP cleavage-activation	Patched domain-containing protein 1 GN=PTCHD1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: patched domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000165188(RNF183)	--	0	0	0	0	0	0	0.021116668	1	0	0	0.020955236	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	zinc-RING finger domain;; Ring finger domain	RING finger protein 183 GN=RNF183 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 183 [Ceratotherium simum simum]
ENSG00000165194(PCDH19)	--	0.00639129	1	0	0	0	0	0.017888383	3	0.021784931	2	0.0252337	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K16499|0|ggo:101125719|PCDH19; protocadherin-19 isoform 1; K16499 protocadherin delta 2 (A)	--	--	--	Cadherin domain;; Cadherin-like	Protocadherin-19 (Precursor) GN=PCDH19 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protocadherin-19 isoform X1 [Equus caballus]
ENSG00000165195(PIGA)	--	5.286588512	262	6.501564781	326	5.184209232	250	6.122766679	312	5.670027333	248	5.747339351	292	0.939974174	0.219963787	normal	0.757043306	-0.413750325	normal	0.942197446	0.214546862	normal	1	0.002078827	normal	[M]	Cell wall/membrane/envelope biogenesis	Biological Process: GPI anchor biosynthetic process (GO:0006506);; 	"K03857|0|hsa:5277|PIGA, GPI3, MCAHS2, PIG-A, PNH1; phosphatidylinositol glycan anchor biosynthesis, class A (EC:2.4.1.198); K03857 phosphatidylinositol glycan, class A [EC:2.4.1.198] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[MOI]	"Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones;; Lipid transport and metabolism"	PIGA (GPI anchor biosynthesis);; Glycosyl transferases group 1;; Glycosyltransferase Family 4;; Glycosyl transferases group 1;; Glycosyl transferase 4-like domain	Phosphatidylinositol N-acetylglucosaminyltransferase subunit A GN=PIGA OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: phosphatidylinositol N-acetylglucosaminyltransferase subunit A isoform X1 [Leptonychotes weddellii]
ENSG00000165197(VEGFD)	--	0.285731	10	0.202703	7	0.630726	21	0.0865871	3	0.194749	6	0.199415	7	--	--	--	--	--	--	0.830667018	-1.410370345	normal	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	"K05449|0|hsa:2277|FIGF, VEGF-D, VEGFD; c-fos induced growth factor (vascular endothelial growth factor D); K05449 vascular endothelial growth factor C/D (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Pathways in cancer (ko05200)	--	--	PDGF/VEGF domain	Vascular endothelial growth factor D (Precursor) GN=FIGF OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vascular endothelial growth factor D [Galeopterus variegatus]
ENSG00000165202(OR1Q1)	--	0	0	0.289062	3	0	0	0.0931813	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:158131|OR1Q1, HSTPCR106, OR1Q2, OR1Q3, OR9-25, OR9-A, OST226, OST226OR9-A, TPCR106; olfactory receptor, family 1, subfamily Q, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 1Q1 GN=OR1Q1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 1Q1-like [Pteropus alecto] 
ENSG00000165209(STRBP)	--	14.75450101	1117	15.88390103	1207	15.97619329	1143	13.30079116	1001	12.26797043	968	13.89110628	998	0.96241992	-0.188745038	normal	0.860446253	-0.339297494	normal	0.958636465	-0.203716435	normal	0.174859629	-0.245938366	normal	--	--	--	K13200|0|ptr:464719|STRBP; spermatid perinuclear RNA binding protein; K13200 spermatid perinuclear RNA-binding protein (A)	--	[R]	General function prediction only	DZF domain;; Double-stranded RNA binding motif;; double strand RNA binding domain from DEAD END PROTEIN 1	Spermatid perinuclear RNA-binding protein GN=STRBP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: spermatid perinuclear RNA-binding protein [Orycteropus afer afer]
ENSG00000165215(CLDN3)	--	6.02712	115	4.79356	93	4.66938	92	2.66458	51	4.775	91	3.36119	65	0.00404358	-1.179568425	down	0.969813166	-0.05193692	normal	0.874759701	-0.499665189	normal	0.19326244	-0.555827133	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|3.03838e-111|ptr:742734|CLDN3; claudin 3; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-3 GN=CLDN3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: claudin-3 [Echinops telfairi]
ENSG00000165219(GAPVD1)	--	10.86650452	1254	12.60783421	1355	12.14081337	1224	12.00551548	1280	11.63794461	1411	8.693582003	1050	0.982230737	-0.001224317	normal	0.982347129	0.036958157	normal	0.951049485	-0.229199604	normal	0.831204751	-0.056829404	normal	--	--	Biological Process: regulation of GTPase activity (GO:0043087);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	GTPase-activator protein for Ras-like GTPase;; Vacuolar sorting protein 9 (VPS9) domain	GTPase-activating protein and VPS9 domain-containing protein 1 GN=GAPVD1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: GTPase-activating protein and VPS9 domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000165233(CARD19)	--	41.27022	472	38.05886	450	43.48946	532	32.05104	378	30.68548	347	23.98175	277	0.834851564	-0.34995685	normal	0.76275384	-0.394899914	normal	7.04E-05	-0.946037698	normal	0.004920587	-0.558952809	normal	--	--	--	--	--	--	--	--	Bcl10-interacting CARD protein GN=C9orf89 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: bcl10-interacting CARD protein isoform X1 [Camelus bactrianus]
ENSG00000165238(WNK2)	--	3.945314121	623	3.551247197	574	4.008351771	637	2.36417753	378	3.335953609	529	2.65434254	398	0.005067217	-0.749279216	normal	0.962441724	-0.138828432	normal	0.02022305	-0.684740436	normal	0.005449647	-0.511697092	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08867|0|hsa:65268|WNK2, NY-CO-43, P/OKcl.13, PRKWNK2, SDCCAG43; WNK lysine deficient protein kinase 2 (EC:2.7.11.1); K08867 WNK lysine deficient protein kinase [EC:2.7.11.1] (A)"	--	--	--	Protein kinase domain;; Protein tyrosine kinase;; Oxidative-stress-responsive kinase 1 C terminal	Serine/threonine-protein kinase WNK2 GN=WNK2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	"PREDICTED: serine/threonine-protein kinase WNK2, partial [Ceratotherium simum simum]"
ENSG00000165240(ATP7A)	--	7.927547	1063	9.011722	1204	7.610713061	1000	5.62084	761	5.519137	733	6.6174275	890	0.287943212	-0.512126079	normal	0.003408216	-0.736178885	normal	0.963594434	-0.176131684	normal	0.002594066	-0.475575319	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion binding (GO:0046872);; 	"K17686|0|hsa:538|ATP7A, DSMAX, MK, MNK, SMAX3; ATPase, Cu++ transporting, alpha polypeptide (EC:3.6.3.54); K17686 Cu+-exporting ATPase [EC:3.6.3.54] (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Heavy-metal-associated domain;; haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase	Copper-transporting ATPase 1 GN=ATP7A OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: copper-transporting ATPase 1 isoform X1 [Galeopterus variegatus]
ENSG00000165244(ZNF367)	--	8.584620057	489	11.319126	656	9.134001	536	7.789663	455	7.431043964	427	8.609217281	496	0.962074135	-0.134362383	normal	0.053758433	-0.639045388	normal	0.965181437	-0.119832754	normal	0.156423173	-0.307887355	normal	[R]	General function prediction only	--	--	--	--	--	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 367 GN=ZNF367 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 367 [Felis catus]
ENSG00000165246(NLGN4Y)	--	4.630460933	345	4.9900469	337	6.16828265	389	1.219998645	89	2.616753409	151	2.452151153	148	1.11E-16	-1.966938434	down	3.18E-06	-1.171555179	down	1.96E-09	-1.393337336	down	6.89E-12	-1.484250993	down	[I]	Lipid transport and metabolism	--	"K07378|0|ptr:449030|NLGN4Y, NLGN4X; neuroligin 4, Y-linked; K07378 neuroligin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	"Neuroligin-4, Y-linked (Precursor) GN=NLGN4Y OS=Homo sapiens (Human) PE=2 SV=1"	T	Signal transduction mechanisms	"PREDICTED: neuroligin-4, X-linked isoform X1 [Mustela putorius furo] "
ENSG00000165259(HDX)	--	1.746651217	87	2.576671144	92	1.561364015	82	1.607419747	98	2.417528585	115	1.467996864	81	0.967639606	0.138626578	normal	0.940405148	0.296140001	normal	0.972846962	-0.025519892	normal	0.800513651	0.150014857	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	Homeobox domain	Highly divergent homeobox GN=HDX OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: highly divergent homeobox [Equus caballus]
ENSG00000165264(NDUFB6)	--	39.53123	612	44.88747	740	46.32338	687	46.43514	750	40.43977	637	42.66775	702	0.923523765	0.261931866	normal	0.937510155	-0.237135551	normal	0.975183382	0.022819796	normal	0.972617855	0.013481321	normal	--	--	--	"K03962|2.07969e-73|ptr:100611615|NDUFB6, CI-B17; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa; K03962 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 6 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit"	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 GN=NDUFB6 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 [Tupaia chinensis]
ENSG00000165269(AQP7)	--	0.559392245	17	0.26729667	9	0.818423217	13	0.224614059	9	0.394679739	11	0.166645628	9	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K08771|0|hsa:364|AQP7, AQP7L, AQP9, AQPap, GLYCQTL; aquaporin 7; K08771 aquaporin-7 (A)"	PPAR signaling pathway (ko03320)	[G]	Carbohydrate transport and metabolism	Major intrinsic protein	Aquaporin-7 GN=AQP7 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-7 [Odobenus rosmarus divergens]
ENSG00000165271(NOL6)	--	18.97021689	1802	17.46919685	1697	19.73076263	1915	19.93408167	1889	21.41153027	2011	17.81360614	1671	0.985739792	0.037160481	normal	0.963919366	0.223316967	normal	0.968327386	-0.20475086	normal	0.950033783	0.019936382	normal	--	--	--	"K14544|0|hsa:65083|NOL6, NRAP, UTP22, bA311H10.1; nucleolar protein 6 (RNA-associated); K14544 U3 small nucleolar RNA-associated protein 22 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[S]	Function unknown	Nrap protein	Nucleolar protein 6 GN=NOL6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nucleolar protein 6 isoform X1 [Myotis davidii] 
ENSG00000165272(AQP3)	--	7.63399	228	1.91007	58	4.33812	131	0.903575	27	1.32007	39	1.27568	38	0	-3.037743466	down	0.905186027	-0.575582437	normal	2.64E-07	-1.753838304	down	0.084946813	-2.023483754	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K09876|0|hsa:360|AQP3, AQP-3, GIL; aquaporin 3 (Gill blood group); K09876 aquaporin-3 (A)"	Vasopressin-regulated water reabsorption (ko04962)	[G]	Carbohydrate transport and metabolism	Major intrinsic protein	Aquaporin-3 GN=AQP3 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-3 [Myotis brandtii] 
ENSG00000165275(TRMT10B)	--	3.660576213	170	2.982672585	139	3.566127319	160	3.897118732	177	3.918575348	175	3.682826905	160	0.967055754	0.027141948	normal	0.917828078	0.307852846	normal	0.9675284	-0.008213807	normal	0.828576192	0.10519047	normal	--	--	--	--	--	[S]	Function unknown	tRNA (Guanine-1)-methyltransferase	tRNA methyltransferase 10 homolog B GN=TRMT10B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tRNA methyltransferase 10 homolog B isoform X1 [Tupaia chinensis]
ENSG00000165280(VCP)	--	133.9826676	10529	135.6838323	11112	132.9055752	10680	151.291981	12083	161.4823402	12653	133.0854286	10710	0.993883536	0.167755147	normal	0.994043039	0.165913252	normal	0.996444381	-0.004244009	normal	0.645795854	0.111629561	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	K13525|0|lve:103080303|VCP; valosin containing protein; K13525 transitional endoplasmic reticulum ATPase (A)	Protein processing in endoplasmic reticulum (ko04141);; Legionellosis (ko05134)	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATPase family associated with various cellular activities (AAA);; Cell division protein 48 (CDC48), N-terminal domain;; AAA ATPase domain;; AAA domain;; Holliday junction DNA helicase ruvB N-terminus;; AAA domain;; AAA domain;; Cell division protein 48 (CDC48), domain 2;; AAA domain (dynein-related subfamily);; AAA domain (Cdc48 subfamily);; AAA domain;; TIP49 C-terminus;; IstB-like ATP binding protein;; AAA domain;; Zeta toxin;; AAA domain;; Archaeal ATPase;; Vps4 C terminal oligomerisation domain;; RNA helicase;; Part of AAA domain;; Magnesium chelatase, subunit ChlI;; AAA domain;; Parvovirus non-structural protein NS1;; ABC transporter;; NACHT domain;; Sigma-54 interaction domain;; KaiC;; Bacterial dnaA  protein;; Protein of unknown function (DUF815);; Type III restriction enzyme, res subunit;; Viral (Superfamily 1) RNA helicase;; Sigma-54 interaction domain"	Transitional endoplasmic reticulum ATPase GN=VCP OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transitional endoplasmic reticulum ATPase [Orcinus orca] 
ENSG00000165282(PIGO)	--	25.43016084	1487	25.22886002	1503	24.45591599	1445	22.881814	1338	24.13422321	1464	32.8057975	1915	0.968908981	-0.182959377	normal	0.982440918	-0.059295559	normal	0.753645463	0.397620833	normal	0.851681247	0.068757584	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; 	"K05288|0|ptr:465068|PIGO; phosphatidylinositol glycan anchor biosynthesis, class O; K05288 phosphatidylinositol glycan, class O (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[T]	Signal transduction mechanisms	Type I phosphodiesterase / nucleotide pyrophosphatase;; Metalloenzyme superfamily	GPI ethanolamine phosphate transferase 3 GN=PIGO OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: GPI ethanolamine phosphate transferase 3 isoform X1 [Galeopterus variegatus]
ENSG00000165283(STOML2)	--	106.70927	2488	106.71327	2533	115.21298	2750	134.42061	3180	133.63834	3112	117.002029	2744	0.92079767	0.323031203	normal	0.954668105	0.275419852	normal	0.989536981	-0.011436283	normal	0.283695781	0.196143694	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[C]	Energy production and conversion	SPFH domain / Band 7 family	"Stomatin-like protein 2, mitochondrial (Precursor) GN=STOML2 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: stomatin-like protein 2, mitochondrial isoform X1 [Leptonychotes weddellii]"
ENSG00000165288(BRWD3)	--	5.296110443	1035	5.811093086	1125	5.088934422	971	4.240792751	837	4.47407862	875	4.339116405	854	0.855107247	-0.336606604	normal	0.773536438	-0.38341052	normal	0.958736742	-0.193205569	normal	0.077603223	-0.308414005	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11798|0|hsa:254065|BRWD3, BRODL, MRX93; bromodomain and WD repeat domain containing 3; K11798 bromodomain and WD repeat domain containing protein 1/3 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Bromodomain"	Bromodomain and WD repeat-containing protein 3 GN=BRWD3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: bromodomain and WD repeat-containing protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000165300(SLITRK5)	--	1.680934192	454	1.575652191	407	1.597854707	421	1.278643527	349	1.24793291	322	1.115558233	295	0.725605477	-0.408714699	normal	0.831855499	-0.357895781	normal	0.396850059	-0.519156865	normal	0.049643087	-0.430014946	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat	SLIT and NTRK-like protein 5 (Precursor) GN=SLITRK5 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	"PREDICTED: SLIT and NTRK-like family, member 5 isoformX3 [Canis lupus familiaris] "
ENSG00000165304(MELK)	--	33.04090382	1446	35.73254714	1555	39.13925711	1702	40.29379807	1800	34.15567398	1485	35.29178201	1554	0.93045571	0.284825406	normal	0.98132156	-0.087790827	normal	0.97811571	-0.139406294	normal	0.9508736	0.019633149	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K08799|0|pps:100970650|MELK; maternal embryonic leucine zipper kinase; K08799 maternal embryonic leucine zipper kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase associated domain 1;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family;; Phosphotransferase enzyme family	Maternal embryonic leucine zipper kinase GN=MELK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: maternal embryonic leucine zipper kinase isoformX1 [Equus caballus]
ENSG00000165309(ARMC3)	--	0.252029785	5	0	0	0.023232085	0	0.0574043	3	0.500512368	4	0.114414838	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Armadillo/beta-catenin-like repeat;; HEAT repeats;; Ethylene-responsive protein kinase Le-CTR1;; HEAT repeat;; HEAT-like repeat;; V-ATPase subunit H;; V-ATPase subunit H;; Myosin-binding striated muscle assembly central;; non-SMC mitotic condensation complex subunit 1;; Armadillo-like	Armadillo repeat-containing protein 3 GN=ARMC3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	hypothetical protein PANDA_000978 [Ailuropoda melanoleuca]
ENSG00000165312(OTUD1)	--	3.36616	137	4.30058	179	3.65409	152	4.76035	197	5.32375	218	6.34802	260	0.713640828	0.48859621	normal	0.929499773	0.260941651	normal	0.040065423	0.760297966	normal	0.079724821	0.507901151	normal	--	--	--	"K13716|0|hsa:220213|OTUD1, DUBA7, OTDC1; OTU deubiquitinase 1 (EC:3.4.19.12); K13716 OTU domain-containing protein 1 [EC:3.4.19.12] (A)"	--	[TO]	"Signal transduction mechanisms;; Posttranslational modification, protein turnover, chaperones"	OTU-like cysteine protease	OTU domain-containing protein 1 GN=OTUD1 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: OTU domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000165322(ARHGAP12)	--	19.56148711	1512	16.68832658	1297	19.53213077	1515	19.944794	1592	19.603831	1554	17.25764822	1372	0.983819533	0.043506848	normal	0.952403781	0.239126459	normal	0.97488486	-0.151170114	normal	0.878575455	0.041879072	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Variant SH3 domain;; PH domain;; Pleckstrin homology domain;; WW domain;; SH3 domain	Rho GTPase-activating protein 12 GN=ARHGAP12 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 12 isoform X1 [Galeopterus variegatus]
ENSG00000165323(FAT3)	--	1.152093943	190	1.678545237	367	0.820952274	175	1.34460843	290	1.496608129	356	1.681188028	340	0.336730053	0.575429871	normal	0.966173856	-0.065057174	normal	0.000494724	0.943931301	normal	0.450086325	0.408175172	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16506|0|hsa:120114|FAT3, CDHF15, CDHR10; FAT atypical cadherin 3; K16506 protocadherin Fat 1/2/3 (A)"	--	[T]	Signal transduction mechanisms	Cadherin domain;; Laminin G domain;; Cadherin-like;; Laminin G domain;; EGF-like domain;; Cadherin prodomain like;; Calcium-binding EGF domain	Protocadherin Fat 3 (Precursor) GN=FAT3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protocadherin Fat 3 [Equus przewalskii]
ENSG00000165325(DEUP1)	--	0.054226781	3	0.029966232	1	0.234544514	1	0	0	0.160881603	2	0.109148112	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Deuterosome protein 1 GN=CCDC67 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 67 [Equus caballus]
ENSG00000165338(HECTD2)	--	4.19605373	256	3.799625739	231	4.442608875	277	4.75268428	284	3.842314254	256	5.211686145	314	0.961089213	0.11824093	normal	0.959013588	0.126040349	normal	0.95281512	0.171706152	normal	0.689284357	0.139981713	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	K12232|0|hsa:143279|HECTD2; HECT domain containing E3 ubiquitin protein ligase 2 (EC:6.3.2.-); K12232 E3 ubiquitin-protein ligase HECTD2 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase)	Probable E3 ubiquitin-protein ligase HECTD2 GN=HECTD2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase HECTD2 [Chrysochloris asiatica]
ENSG00000165355(FBXO33)	--	5.58628168	284	4.97654709	286	5.221792168	289	6.662629767	383	6.539984085	322	7.656245511	408	0.767079075	0.398757679	normal	0.956026722	0.148876765	normal	0.516696052	0.487053003	normal	0.15062618	0.352669815	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10310|0|hsa:254170|FBXO33, BMND12, Fbx33, c14_5247; F-box protein 33; K10310 F-box protein 33 (A)"	--	--	--	F-box-like;; F-box domain	F-box only protein 33 GN=FBXO33 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box only protein 33 [Ceratotherium simum simum]
ENSG00000165359(INTS6L)	--	1.544874021	103	1.890920784	125	0.969407343	67	0.16983645	11	0.348619422	24	0.123131364	8	1.10E-13	-3.088519833	down	5.74E-11	-2.33067682	down	2.01E-08	-2.856039371	down	8.37E-07	-2.800529056	down	--	--	--	K13180|0|pps:100985337|DDX26B; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B; K13180 ATP-dependent RNA helicase DDX26B [EC:3.6.4.-] (A)	--	[R]	General function prediction only	INTS6/SAGE1/DDX26B/CT45 C-terminus;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Protein DDX26B GN=DDX26B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein DDX26B-like isoform 1 [Ceratotherium simum simum]
ENSG00000165376(CLDN2)	--	1.332057	75	0.793082	45	1.41503	80	7.7970034	440	19.528876	1096	15.9182436	902	0	2.497844066	up	0	4.539417877	up	0	3.462247159	up	1.34E-05	3.589069086	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|6.01691e-121|ggo:101152797|CLDN2; claudin-2 isoform 1; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-2 GN=CLDN2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: claudin-2 [Tupaia chinensis]
ENSG00000165389(SPTSSA)	--	36.93823118	1404	26.00613325	998	30.15599215	1137	32.71667363	1270	36.5936592	1387	43.49130507	1659	0.969521471	-0.17534483	normal	0.554446462	0.452845055	normal	0.197922968	0.536196376	normal	0.35879938	0.265942828	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3317)	Serine palmitoyltransferase small subunit A GN=SPTSSA OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine palmitoyltransferase small subunit A-like [Myotis lucifugus]
ENSG00000165392(WRN)	--	6.67133	707	7.60234	828	7.24861	770	6.17762	671	6.85028	731	5.66828	609	0.970092517	-0.105993225	normal	0.953447062	-0.2007953	normal	0.83557792	-0.345941848	normal	0.293659476	-0.21828053	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: intracellular (GO:0005622);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Biological Process: DNA replication (GO:0006260);; Biological Process: DNA repair (GO:0006281);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; Molecular Function: ATP-dependent 3'-5' DNA helicase activity (GO:0043140);; 	"K10900|0|hsa:7486|WRN, RECQ3, RECQL2, RECQL3; Werner syndrome, RecQ helicase-like (EC:3.6.4.12); K10900 werner syndrome ATP-dependent helicase [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	3'-5' exonuclease;; DEAD/DEAH box helicase;; RQC domain;; Helicase conserved C-terminal domain;; Helix-turn-helix domain;; HRDC domain	Werner syndrome ATP-dependent helicase GN=WRN OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase [Lipotes vexillifer]
ENSG00000165406(MARCH8)	--	11.87011162	963	12.78829865	905	10.6898397	883	8.6511942	755	9.3717436	839	12.26462603	938	0.766114776	-0.381202552	normal	0.969886058	-0.130447075	normal	0.976043357	0.078752165	normal	0.530077875	-0.140291616	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10656|0|ptr:450431|MARCH8; membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase; K10656 E3 ubiquitin-protein ligase MARCH1/8 [EC:6.3.2.19] (A)"	--	[A]	RNA processing and modification	RING-variant domain	E3 ubiquitin-protein ligase MARCH8 GN=MARCH8 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: E3 ubiquitin-protein ligase MARCH8 isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000165409(TSHR)	--	0	0	0	0	0.0530605	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04249|0|hsa:7253|TSHR, CHNG1, LGR3, hTSHR-I; thyroid stimulating hormone receptor; K04249 thyroid stimulating hormone receptor (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Thyroid hormone synthesis (ko04918);; Autoimmune thyroid disease (ko05320)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family);; Leucine rich repeat;; Leucine rich repeats (6 copies)	Thyrotropin receptor (Precursor) GN=TSHR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: thyrotropin receptor [Leptonychotes weddellii]
ENSG00000165410(CFL2)	--	53.3464462	2178	52.5777554	2294	50.66157041	2251	60.58363791	2723	50.37742172	2196	56.240272	2482	0.940339568	0.291176754	normal	0.985768212	-0.08435705	normal	0.983505783	0.132560774	normal	0.580229312	0.117051061	normal	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	K05765|5.0958e-117|ssc:497233|CFL2; cofilin 2 (muscle); K05765 cofilin (A)	Axon guidance (ko04360);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Pertussis (ko05133)	[Z]	Cytoskeleton	Cofilin/tropomyosin-type actin-binding protein	Cofilin-2 GN=CFL2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: cofilin-2 isoform X2 [Equus caballus]
ENSG00000165416(SUGT1)	--	21.64111124	767	19.74996124	755	21.74530229	815	23.18208135	922	17.35559103	772	16.26584421	713	0.942369932	0.23427941	normal	0.975820709	0.010676497	normal	0.953477074	-0.200790764	normal	0.952709638	0.020696738	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K12795|0|ptr:452744|SUGT1; SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae); K12795 suppressor of G2 allele of SKP1 (A)"	NOD-like receptor signaling pathway (ko04621)	[T]	Signal transduction mechanisms	SGS domain;; CS domain;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Suppressor of G2 allele of SKP1 homolog GN=SUGT1 OS=Homo sapiens (Human) PE=1 SV=3	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: suppressor of G2 allele of SKP1 homolog [Ceratotherium simum simum]
ENSG00000165417(GTF2A1)	--	8.634345959	747	9.180761263	795	7.989452736	677	9.095693	795	8.410297093	729	8.963273237	778	0.975066011	0.058896923	normal	0.965580899	-0.146172117	normal	0.955328605	0.191922663	normal	0.920513145	0.031447572	normal	--	--	Cellular Component: transcription factor TFIIA complex (GO:0005672);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	"K03122|2.51039e-141|pps:100973812|GTF2A1; general transcription factor IIA, 1, 19/37kDa; K03122 transcription initiation factor TFIIA large subunit (A)"	Basal transcription factors (ko03022);; Viral carcinogenesis (ko05203)	[K]	Transcription	"Transcription factor IIA, alpha/beta subunit"	Transcription initiation factor IIA beta chain GN=GTF2A1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor IIA subunit 1 [Oryctolagus cuniculus]
ENSG00000165424(ZCCHC24)	--	5.648971005	513	4.66902509	310	4.1924956	379	4.44160375	389	4.428759346	400	2.179259248	198	0.660457856	-0.428541631	normal	0.850455291	0.344820867	normal	0.000325123	-0.939708978	normal	0.623727906	-0.307151969	normal	--	--	--	--	--	--	--	Zinc knuckle;; Zinc-binding domain	Zinc finger CCHC domain-containing protein 24 GN=ZCCHC24 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger CCHC domain-containing protein 24 [Canis lupus familiaris] 
ENSG00000165434(PGM2L1)	--	4.388077	573	4.132595767	564	4.517370449	604	9.862166	1238	10.09564486	1337	8.445252543	1152	6.88E-08	1.078558398	up	4.57E-10	1.221614298	up	1.52E-05	0.921529576	normal	6.30E-14	1.076872142	up	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: intramolecular transferase activity, phosphotransferases (GO:0016868);; Biological Process: organic substance metabolic process (GO:0071704);; "	"K11809|0|hsa:283209|PGM2L1, BM32A; phosphoglucomutase 2-like 1 (EC:2.7.1.106); K11809 glucose-1,6-bisphosphate synthase [EC:2.7.1.106] (A)"	Starch and sucrose metabolism (ko00500)	[G]	Carbohydrate transport and metabolism	"Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III;; Phosphoglucomutase/phosphomannomutase, C-terminal domain"	"Glucose 1,6-bisphosphate synthase GN=PGM2L1 OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: glucose 1,6-bisphosphate synthase [Physeter catodon]"
ENSG00000165443(PHYHIPL)	--	0.882774	45	0.834203	42	0.692788	34	0.388111007	20	0.358845	18	0.696475	36	0.466992634	-1.140803454	normal	0.474364947	-1.177263933	normal	0.982766211	0.071097181	normal	0.231874146	-0.729221196	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Fibronectin type III domain	Phytanoyl-CoA hydroxylase-interacting protein-like GN=PHYHIPL OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: phytanoyl-CoA hydroxylase-interacting protein-like isoform 2 [Dasypus novemcinctus] 
ENSG00000165449(SLC16A9)	--	1.597853562	91	2.48494762	147	1.620924288	90	1.44158849	87	1.105942698	68	0.969651101	60	0.970440048	-0.094058986	normal	0.002208664	-1.116326756	down	0.811143391	-0.581211845	normal	0.181004813	-0.632315631	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08186|0|hsa:220963|SLC16A9, C10orf36, MCT9; solute carrier family 16, member 9; K08186 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 9 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 9 GN=SLC16A9 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 9 [Tupaia chinensis] 
ENSG00000165458(INPPL1)	--	29.3757769	2847	33.01828164	3036	32.68691256	2869	35.16012424	2711	40.25377539	2966	34.59409403	2971	0.987289692	-0.101393559	normal	0.98933307	-0.055052006	normal	0.989662832	0.042087394	normal	0.889033249	-0.038191713	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15909|0|hsa:3636|INPPL1, OPSMD, SHIP2; inositol polyphosphate phosphatase-like 1 (EC:3.1.3.86); K15909 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2 [EC:3.1.3.86] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; B cell receptor signaling pathway (ko04662);; Fc gamma R-mediated phagocytosis (ko04666);; Insulin signaling pathway (ko04910)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endonuclease/Exonuclease/phosphatase family;; SH2 domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	"Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 GN=INPPL1 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2, partial [Felis catus]"
ENSG00000165474(GJB2)	--	1.428978212	53	0.505796939	19	0.926384186	34	0.773090391	29	0.993813385	37	0.426703944	16	0.718943829	-0.866310265	normal	0.862660504	0.88861445	normal	0.813781671	-1.027707628	normal	0.710572572	-0.392642053	normal	--	--	--	"K07621|2.807e-167|pps:100970213|GJB2; gap junction protein, beta 2, 26kDa; K07621 gap junction protein, beta 2 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction beta-2 protein GN=GJB2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: gap junction beta-2 protein [Tupaia chinensis] 
ENSG00000165475(CRYL1)	--	9.150630999	234	7.431866355	192	6.650629991	174	8.296305319	214	9.442254924	240	6.254997273	161	0.955780382	-0.158640265	normal	0.909446645	0.298395659	normal	0.962315158	-0.119240374	normal	0.985016047	0.013471817	normal	[I]	Lipid transport and metabolism	Molecular Function: 3-hydroxyacyl-CoA dehydrogenase activity (GO:0003857);; Biological Process: fatty acid metabolic process (GO:0006631);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K13247|0|pps:100972837|CRYL1; crystallin, lambda 1; K13247 L-gulonate 3-dehydrogenase [EC:1.1.1.45] (A)"	Pentose and glucuronate interconversions (ko00040)	[I]	Lipid transport and metabolism	"3-hydroxyacyl-CoA dehydrogenase, NAD binding domain;; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain"	Lambda-crystallin homolog GN=CRYL1 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: lambda-crystallin homolog isoform X2 [Mustela putorius furo]
ENSG00000165476(REEP3)	--	28.2669	1866	31.4651	2054	28.1087	1804	31.1845	2089	30.2881	2006	27.1094	1796	0.981396461	0.131928543	normal	0.985868387	-0.055499784	normal	0.985841324	-0.014691088	normal	0.949356766	0.019697431	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K17338|8.89609e-165|hsa:221035|REEP3, C10orf74; receptor accessory protein 3; K17338 receptor expression-enhancing protein 1/2/3/4 (A)"	--	[V]	Defense mechanisms	"TB2/DP1, HVA22 family"	Receptor expression-enhancing protein 3 GN=REEP3 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: receptor expression-enhancing protein 3-like [Pteropus alecto]
ENSG00000165480(SKA3)	--	7.139386	363	8.449186	429	8.454964	425	8.239367	416	7.496356	387	8.024736	410	0.954923403	0.165128494	normal	0.953577235	-0.169441411	normal	0.968540528	-0.059913303	normal	0.953297381	-0.025917744	normal	--	--	--	--	--	--	--	--	Spindle and kinetochore-associated protein 3 GN=SKA3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: spindle and kinetochore-associated protein 3 [Oryctolagus cuniculus]
ENSG00000165487(MICU2)	--	19.54665643	577	15.43604051	480	15.39171916	471	16.69900674	526	18.08152904	561	15.50170837	482	0.958343133	-0.163883495	normal	0.946868062	0.202947886	normal	0.971093745	0.0249355	normal	0.968686158	0.016651354	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[P]	Inorganic ion transport and metabolism	EF-hand domain pair;; EF hand;; EF-hand domain pair;; EF-hand domain	"Calcium uptake protein 2, mitochondrial (Precursor) GN=MICU2 OS=Homo sapiens (Human) PE=1 SV=2"	P	Inorganic ion transport and metabolism	PREDICTED: EF-hand domain-containing family member A1 [Ceratotherium simum simum]
ENSG00000165490(DDIAS)	--	10.53263808	523	9.036360441	488	11.41531129	624	9.504870278	504	9.475508874	433	9.70893881	482	0.968751808	-0.083968165	normal	0.948558698	-0.193304273	normal	0.773810782	-0.379754123	normal	0.331760229	-0.225403228	normal	--	--	--	--	--	--	--	Replication factor-A C terminal domain	DNA damage-induced apoptosis suppressor protein GN=DDIAS OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: nitric oxide-inducible gene protein [Ceratotherium simum simum]
ENSG00000165494(PCF11)	--	12.43785615	1174	15.06500832	1397	12.95357618	1172	14.0291002	1251	15.05626712	1219	14.93005829	1412	0.9804462	0.060740108	normal	0.95818789	-0.217807809	normal	0.93945989	0.260169812	normal	0.911558094	0.031557061	normal	--	--	--	K14400|0|hsa:51585|PCF11; PCF11 cleavage and polyadenylation factor subunit; K14400 pre-mRNA cleavage complex 2 protein Pcf11 (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	RNA polymerase II-binding domain.	Pre-mRNA cleavage complex 2 protein Pcf11 GN=PCF11 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: pre-mRNA cleavage complex 2 protein Pcf11 [Leptonychotes weddellii]
ENSG00000165495(PKNOX2)	--	0.01148281	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein PKNOX2 GN=PKNOX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein PKNOX2 isoform X1 [Orycteropus afer afer] 
ENSG00000165501(LRR1)	--	21.18191	375	20.21149	377	22.53869	422	23.66214	454	20.06419	369	17.96135	344	0.929252192	0.244059584	normal	0.967108657	-0.052158775	normal	0.892312708	-0.301925301	normal	0.94503496	-0.030505807	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K10348|0|hsa:122769|LRR1, 4-1BBLRR, LRR-1, PPIL5; leucine rich repeat protein 1; K10348 LRR-repeat protein 1 (A)"	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeat	Leucine-rich repeat protein 1 GN=LRR1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leucine-rich repeat protein 1 isoform X1 [Tupaia chinensis]
ENSG00000165502(RPL36AL)	--	179.291	1830	188.438	1977	192.74	2017	210.133	2241	199.697	2026	207.599	2157	0.951392063	0.261268248	normal	0.986489526	0.013884254	normal	0.985154873	0.088459505	normal	0.570896959	0.120205628	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02929|1.27958e-70|ptr:465760|RPL36A, RPL36AL; ribosomal protein L36a; K02929 large subunit ribosomal protein L44e (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L44	60S ribosomal protein L36a-like GN=RPL36AL OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L36a [Vicugna pacos]
ENSG00000165506(DNAAF2)	--	6.870905	326	8.3056	319	7.98518	366	8.46103	382	10.6924	455	9.1117	366	0.946653449	0.197010015	normal	0.499094087	0.488933502	normal	0.969078065	-0.008257323	normal	0.384792933	0.229883075	normal	--	--	--	--	--	--	--	pre-RNA processing PIH1/Nop17	Protein kintoun GN=DNAAF2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein kintoun [Felis catus]
ENSG00000165507(C10orf10)	--	0.857294	34	0.717552	29	0.219395	8	0.426502	17	0.320467	12	1.24602	50	0.85039664	-0.967821852	normal	0.769544178	-1.194815233	normal	5.45E-05	2.429541754	up	0.958786346	0.134536108	normal	--	--	--	--	--	--	--	Decidual protein induced by progesterone family	Protein DEPP GN=DEPP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein DEPP [Tupaia chinensis]
ENSG00000165512(ZNF22)	--	7.6279	284	6.08812	219	6.23151	221	8.19081	300	8.04744	294	7.17603	258	0.966692399	0.047986713	normal	0.793967309	0.401060805	normal	0.943464214	0.213678735	normal	0.497774267	0.213083882	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 22 GN=ZNF22 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 22 [Felis catus] 
ENSG00000165516(KLHDC2)	--	17.57575	580	16.12947003	513	15.38737386	507	15.61123032	520	17.05982003	559	17.75958	580	0.952450393	-0.187847646	normal	0.966876458	0.102174303	normal	0.953210839	0.185258709	normal	0.932053401	0.031290822	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Kelch motif"	Kelch domain-containing protein 2 GN=KLHDC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: kelch domain-containing protein 2 [Galeopterus variegatus]
ENSG00000165521(EML5)	--	2.383245948	411	2.52330461	437	2.364987261	403	2.053602012	357	2.260364503	389	2.419730005	417	0.934120104	-0.233110571	normal	0.948987237	-0.188597449	normal	0.969261633	0.040825491	normal	0.675239963	-0.126043069	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K18597|0|hsa:161436|EML5, EMAP-2; echinoderm microtubule associated protein like 5; K18597 echinoderm microtubule-associated protein-like 5 (A)"	--	[S]	Function unknown	"WD domain, G-beta repeat;; HELP motif;; Nup133 N terminal like"	Echinoderm microtubule-associated protein-like 5 GN=EML5 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: echinoderm microtubule-associated protein-like 5 [Ceratotherium simum simum]
ENSG00000165525(NEMF)	--	10.68165851	1106	14.57239829	1473	16.25051713	1492	14.07274872	1462	13.88944675	1281	14.53446783	1333	0.803447803	0.371309794	normal	0.957700151	-0.222668134	normal	0.971396936	-0.170679064	normal	0.95908328	-0.019536254	normal	[K]	Transcription	--	--	--	[R]	General function prediction only	Fibronectin-binding protein A N-terminus (FbpA);; Domain of unknown function (DUF3441);; Domain of unknown function (DUF814)	Nuclear export mediator factor NEMF GN=NEMF OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: nuclear export mediator factor NEMF [Panthera tigris altaica]
ENSG00000165526(RPUSD4)	--	7.458061043	355	7.354361	355	7.651264	343	6.603099	315	7.454042	351	7.878216442	374	0.945025088	-0.202368925	normal	0.967278736	-0.037613409	normal	0.962534927	0.116048128	normal	0.923805752	-0.038638397	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	--	--	[A]	RNA processing and modification	RNA pseudouridylate synthase	RNA pseudouridylate synthase domain-containing protein 4 GN=RPUSD4 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: RNA pseudouridylate synthase domain-containing protein 4 [Galeopterus variegatus]
ENSG00000165527(ARF6)	--	41.2446	2450	45.6121	2735	50.0474	2957	67.6381	4074	55.1114	3279	55.3747	3307	0.004810562	0.70248696	normal	0.969188442	0.240167091	normal	0.98480032	0.153023323	normal	0.028656077	0.367068708	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07941|1.51164e-127|umr:103665472|ARF6; ADP-ribosylation factor 6; K07941 ADP-ribosylation factor 6 (A)	Ras signaling pathway (ko04014);; Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Signal recognition particle receptor beta subunit;; Gtr1/RagA G protein conserved region;; Miro-like protein	ADP-ribosylation factor 6 GN=ARF6 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor 6 [Pteropus alecto] 
ENSG00000165533(TTC8)	--	18.94647549	598	20.36675026	603	19.88020254	609	20.84519943	597	20.65579384	637	20.77358767	589	0.97313655	-0.033161544	normal	0.971973911	0.057568335	normal	0.972355386	-0.056323808	normal	0.981071284	-0.01084042	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16781|0|hsa:123016|TTC8, BBS8, RP51; tetratricopeptide repeat domain 8; K16781 tetratricopeptide repeat protein 8 (A)"	--	[R]	General function prediction only	"Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat"	Tetratricopeptide repeat protein 8 GN=TTC8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 8 isoform X2 [Ursus maritimus]
ENSG00000165548(TMEM63C)	--	8.635938382	667	8.134977474	636	7.2626558	562	6.938004031	527	7.820944794	575	7.197166858	531	0.791726025	-0.369755256	normal	0.958464555	-0.166474834	normal	0.969034961	-0.089900796	normal	0.344197875	-0.213018057	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[R]	General function prediction only	"Domain of unknown function DUF221;; Late exocytosis, associated with Golgi transport;; Domain of unknown function (DUF4463)"	Calcium permeable stress-gated cation channel 1 GN=TMEM63C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 63C [Galeopterus variegatus]
ENSG00000165555(NOXRED1)	--	0.612038387	16	0.115183498	3	0.32067109	8	0.344736477	9	0.452013	12	0.46225661	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	NADP oxidoreductase coenzyme F420-dependent	NADP-dependent oxidoreductase domain-containing protein 1 GN=NOXRED1 OS=Homo sapiens (Human) PE=2 SV=2	E	Amino acid transport and metabolism	PREDICTED: NADP-dependent oxidoreductase domain-containing protein 1 [Galeopterus variegatus]
ENSG00000165556(CDX2)	--	0.329925	24	0.312134	23	0.265038	19	0.109329	8	0.158945	11	0.216074	16	0.722287791	-1.448453815	normal	0.9320855	-0.989630618	normal	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: multicellular organismal development (GO:0007275);; "	K09312|1.54038e-126|pps:100978486|CDX2; caudal type homeobox 2; K09312 homeobox protein CDX (A)	--	[K]	Transcription	Caudal like protein activation region;; Homeobox domain	Homeobox protein CDX-2 GN=CDX2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein CDX-2 [Loxodonta africana]
ENSG00000165568(AKR1E2)	--	5.936571327	299	6.549203021	302	9.111350746	371	8.830099327	447	7.788023519	356	7.991758528	459	0.292135827	0.546984562	normal	0.940277216	0.21491004	normal	0.894907081	0.297690638	normal	0.125208045	0.355859037	normal	[R]	General function prediction only	--	"K13981|0|hsa:83592|AKR1E2, AKR1CL2, AKRDC1, LoopADR, hTSP, htAKR; aldo-keto reductase family 1, member E2 (EC:1.1.1.263); K13981 1,5-anhydro-D-fructose reductase [EC:1.1.1.263] (A)"	--	[R]	General function prediction only	Aldo/keto reductase family	"1,5-anhydro-D-fructose reductase GN=AKR1E2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: LOW QUALITY PROTEIN: 1,5-anhydro-D-fructose reductase-like [Myotis davidii]"
ENSG00000165572(KBTBD6)	--	3.06245	259	3.92851	335	4.28478	361	3.62456	309	3.74517	316	3.64835	309	0.93916012	0.222612289	normal	0.962202675	-0.105174147	normal	0.935163295	-0.231633493	normal	0.895946735	-0.052941841	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10474|0|ptr:452556|KBTBD6; kelch repeat and BTB (POZ) domain containing 6; K10474 kelch repeat and BTB domain-containing protein 6/7 (A)	--	--	--	"BTB/POZ domain;; BTB And C-terminal Kelch;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif"	Kelch repeat and BTB domain-containing protein 6 GN=KBTBD6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: kelch repeat and BTB domain-containing protein 6 [Equus przewalskii]
ENSG00000165591(FAAH2)	--	0.0297414	1	0	0	0.0584289	1	0.323429	11	0.49293	16	0.473575	16	--	--	--	--	--	--	--	--	--	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	--	--	--	[JIT]	"Translation, ribosomal structure and biogenesis;; Lipid transport and metabolism;; Signal transduction mechanisms"	Amidase	Fatty-acid amide hydrolase 2 GN=FAAH2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: fatty-acid amide hydrolase 2-like [Vicugna pacos]
ENSG00000165609(NUDT5)	--	35.136336	1396	37.72635	1476	40.17703	1512	41.18579001	1687	37.963251	1778	39.873717	1607	0.952705352	0.242086118	normal	0.952471583	0.246905278	normal	0.982482572	0.079543167	normal	0.313199848	0.18909794	normal	[LR]	"Replication, recombination and repair;; General function prediction only"	Molecular Function: hydrolase activity (GO:0016787);; 	"K13987|5.70154e-149|hsa:11164|NUDT5, YSA1, YSA1H, YSAH1, hYSAH1; nudix (nucleoside diphosphate linked moiety X)-type motif 5 (EC:3.6.1.13 3.6.1.58); K13987 ADP-sugar pyrophosphatase / 8-oxo-dGDP phosphatase [EC:3.6.1.13 3.6.1.58 3.6.1.-] (A)"	Purine metabolism (ko00230)	[L]	"Replication, recombination and repair"	NUDIX domain	ADP-sugar pyrophosphatase GN=NUDT5 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: ADP-sugar pyrophosphatase isoform X1 [Tupaia chinensis] 
ENSG00000165617(DACT1)	--	0.258679657	10	0.194379525	13	0.136423658	7	1.016317616	63	1.5835394	104	1.039167052	70	2.39E-06	2.455501082	up	3.89E-12	2.841907743	up	1.74E-09	3.063105143	up	1.67E-08	2.960306958	up	--	--	--	--	--	--	--	Dapper	Dapper homolog 1 GN=DACT1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dapper homolog 1 isoform 1 [Trichechus manatus latirostris]
ENSG00000165621(OXGR1)	--	0.120935615	4	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08419|0|hsa:27199|OXGR1, GPR80, GPR99, P2RY15, P2Y15, aKGR; oxoglutarate (alpha-ketoglutarate) receptor 1; K08419 oxoglutarate (alpha-ketoglutarate) receptor 1 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	2-oxoglutarate receptor 1 GN=OXGR1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: 2-oxoglutarate receptor 1 [Balaenoptera acutorostrata scammoni]
ENSG00000165626(BEND7)	--	4.67851246	423	5.55695367	466	5.033933327	415	7.19823987	634	6.361741842	560	5.047063375	483	0.212487319	0.551347208	normal	0.930762192	0.242950258	normal	0.943869801	0.209910746	normal	0.1004009	0.340787762	normal	--	--	--	--	--	--	--	BEN domain	BEN domain-containing protein 7 GN=BEND7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: BEN domain-containing protein 7 [Orycteropus afer afer]
ENSG00000165629(ATP5C1)	--	110.28671	2202	102.1731	2036	107.39343	2149	116.44814	2349	111.3156	2183	107.4888	2146	0.987063434	0.062357852	normal	0.985373184	0.079091271	normal	0.987502357	-0.010299596	normal	0.873825493	0.042841558	normal	[C]	Energy production and conversion	"Biological Process: ATP synthesis coupled proton transport (GO:0015986);; Cellular Component: proton-transporting ATP synthase complex, catalytic core F(1) (GO:0045261);; Molecular Function: proton-transporting ATP synthase activity, rotational mechanism (GO:0046933);; "	"K02136|0|ptr:450294|ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; K02136 F-type H+-transporting ATPase subunit gamma (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	ATP synthase	"ATP synthase subunit gamma, mitochondrial (Precursor) GN=ATP5C1 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: ATP synthase subunit gamma, mitochondrial isoform X1 [Ochotona princeps] "
ENSG00000165630(PRPF18)	--	9.765233783	558	10.1541868	534	10.228618	579	10.09773696	521	9.902598034	628	9.503463209	631	0.964211343	-0.129445038	normal	0.945186706	0.211944291	normal	0.967529728	0.115496172	normal	0.818071942	0.070705978	normal	--	--	Cellular Component: spliceosomal complex (GO:0005681);; Biological Process: RNA splicing (GO:0008380);; 	K12817|0|ocu:100340516|PRPF18; pre-mRNA processing factor 18; K12817 pre-mRNA-splicing factor 18 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	Prp18 domain;; pre-mRNA processing factor 4 (PRP4) like	Pre-mRNA-splicing factor 18 GN=PRPF18 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pre-mRNA-splicing factor 18 [Oryctolagus cuniculus]
ENSG00000165632(TAF3)	--	4.061774	439	4.226796273	451	4.137144787	441	4.633707385	499	4.734512645	510	5.968262684	646	0.958713721	0.153482551	normal	0.957942359	0.155452847	normal	0.24074785	0.540922462	normal	0.175343418	0.293871872	normal	--	--	--	"K14650|0|hsa:83860|TAF3, TAF140, TAFII-140, TAFII140; TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa; K14650 transcription initiation factor TFIID subunit 3 (A)"	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	--	--	Bromodomain associated;; PHD-finger	Transcription initiation factor TFIID subunit 3 GN=TAF3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 3 [Ovis aries]
ENSG00000165633(VSTM4)	--	0.294246322	27	0.551607546	39	0.36554997	22	0.077531739	10	0.4487186	35	0.054151803	7	0.720759353	-1.334554659	normal	0.979317304	-0.17056042	normal	0.76969813	-1.473084436	normal	0.469077809	-0.780701192	normal	--	--	--	--	--	--	--	Immunoglobulin V-set domain	Peptide Lv (Precursor) GN=VSTM4 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: V-set and transmembrane domain-containing protein 4 [Bubalus bubalis]
ENSG00000165637(VDAC2)	--	152.4964406	3817	155.8268063	3873	153.9826925	3795	123.4875898	3137	109.9794032	2711	112.161746	2792	0.937472638	-0.313746343	normal	0.263846682	-0.53580145	normal	0.629869994	-0.450882058	normal	0.004128238	-0.432268544	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: transmembrane transport (GO:0055085);; 	"K15040|0|hsa:7417|VDAC2, POR; voltage-dependent anion channel 2; K15040 voltage-dependent anion channel protein 2 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Parkinson's disease (ko05012);; Huntington's disease (ko05016);; HTLV-I infection (ko05166)	[P]	Inorganic ion transport and metabolism	Eukaryotic porin	Voltage-dependent anion-selective channel protein 2 GN=VDAC2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent anion-selective channel protein 2 isoform X4 [Balaenoptera acutorostrata scammoni]
ENSG00000165644(COMTD1)	--	18.68490328	241	16.68200506	223	18.54230431	254	17.72590322	235	20.23230287	262	20.416203	267	0.965248654	-0.066773529	normal	0.943149666	0.209782915	normal	0.965641494	0.063351882	normal	0.875136822	0.068989908	normal	[R]	General function prediction only	Molecular Function: O-methyltransferase activity (GO:0008171);; 	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	O-methyltransferase;; Methyltransferase domain;; Methyltransferase domain	Catechol O-methyltransferase domain-containing protein 1 GN=COMTD1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: catechol O-methyltransferase domain-containing protein 1 [Galeopterus variegatus]
ENSG00000165646(SLC18A2)	--	0.0334335	2	0	0	0.0165834	0	0	0	0.016161	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08155|0|hsa:6571|SLC18A2, SVAT, SVMT, VAT2, VMAT2; solute carrier family 18 (vesicular monoamine transporter), member 2; K08155 MFS transporter, DHA1 family, solute carrier family 18 (vesicular amine transporter), member 1/2 (A)"	Synaptic vesicle cycle (ko04721);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Major Facilitator Superfamily;; Sugar (and other) transporter	Synaptic vesicular amine transporter GN=SLC18A2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptic vesicular amine transporter [Loxodonta africana]
ENSG00000165650(PDZD8)	--	22.6272	3569	22.0993	3454	21.4087	3307	25.994	4118	32.4885	5136	25.4029	4025	0.98481796	0.17552128	normal	0.230498859	0.550751614	normal	0.961273724	0.275060108	normal	0.050606164	0.341077904	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[R]	General function prediction only	PDZ domain;; PDZ domain (Also known as DHR or GLGF);; Phorbol esters/diacylglycerol binding domain (C1 domain)	PDZ domain-containing protein 8 GN=PDZD8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: PDZ domain containing 8 [Lipotes vexillifer]
ENSG00000165655(ZNF503)	--	18.05	982	11.0188	609	11.4913	647	15.4671	845	18.7088	1025	13.7593	759	0.937742773	-0.247186526	normal	0.005020807	0.72827442	normal	0.944769617	0.221564117	normal	0.643260708	0.21069504	normal	--	--	--	--	--	--	--	NocA-like zinc-finger protein 1	Zinc finger protein 503 GN=ZNF503 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 503 [Trichechus manatus latirostris]
ENSG00000165660(FAM175B)	--	8.62447	437	7.61025	380	9.12265	452	9.82166	498	9.5628	483	7.73055	392	0.957968832	0.157162342	normal	0.870077492	0.323453075	normal	0.94241877	-0.21299464	normal	0.768535353	0.092000804	normal	--	--	--	--	--	--	--	--	BRISC complex subunit Abro1 GN=FAM175B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: BRISC complex subunit Abro1 [Canis lupus familiaris]
ENSG00000165661(QSOX2)	--	25.06991595	2092	24.602864	2087	24.68479	2080	18.85933114	1573	17.32712288	1434	19.5475789	1623	0.603312619	-0.441820781	normal	0.143255961	-0.562317465	normal	0.836341983	-0.36590999	normal	0.00207248	-0.456066094	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Molecular Function: thiol oxidase activity (GO:0016972);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K10758|0|hsa:169714|QSOX2, QSCN6L1, SOXN; quiescin Q6 sulfhydryl oxidase 2 (EC:1.8.3.2); K10758 thiol oxidase [EC:1.8.3.2] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Erv1 / Alr family;; Thioredoxin	Sulfhydryl oxidase 2 (Precursor) GN=QSOX2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: uncharacterized protein LOC101388399 [Ceratotherium simum simum]
ENSG00000165669(FAM204A)	--	12.07663144	479	14.09165244	572	14.41310423	487	19.1689936	703	16.16968233	616	17.24837163	614	0.294367581	0.521279098	normal	0.969636602	0.085271375	normal	0.864813588	0.325124384	normal	0.127807431	0.307974155	normal	--	--	--	--	--	--	--	--	Protein FAM204A GN=FAM204A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM204A isoform X2 [Galeopterus variegatus]
ENSG00000165671(NSD1)	--	16.60662116	2454	17.24333234	2850	14.8855636	2572	13.94476329	2418	15.78846206	2869	17.35326666	2877	0.987973925	-0.052120393	normal	0.989552294	-0.01183425	normal	0.983182123	0.153297872	normal	0.911558094	0.031098083	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15588|0|hsa:64324|NSD1, ARA267, KMT3B, SOTOS, SOTOS1, STO; nuclear receptor binding SET domain protein 1 (EC:2.1.1.43); K15588 histone-lysine N-methyltransferase NSD1 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[K]	Transcription	PWWP domain;; SET domain;; PHD-finger;; PHD-finger	"Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific GN=NSD1 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific isoform 1 [Odobenus rosmarus divergens]"
ENSG00000165672(PRDX3)	--	210.63	4611	237.066	5127	234.641	5017	243.332	5369	221.132	4846	220.532	4839	0.986248272	0.188683171	normal	0.991579413	-0.102715881	normal	0.99281056	-0.060388905	normal	0.984925516	0.007441864	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: peroxiredoxin activity (GO:0051920);; Biological Process: oxidation-reduction process (GO:0055114);; 	K03386|0|ptr:741184|PRDX3; peroxiredoxin 3; K03386 peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	AhpC/TSA family;; Redoxin;; C-terminal domain of 1-Cys peroxiredoxin	"Thioredoxin-dependent peroxide reductase, mitochondrial (Precursor) GN=PRDX3 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: thioredoxin-dependent peroxide reductase, mitochondrial [Ailuropoda melanoleuca]"
ENSG00000165675(ENOX2)	--	5.827138265	262	4.396841011	292	4.809749805	296	7.007645102	327	7.264440138	340	6.6676543	326	0.907987223	0.287380601	normal	0.945624349	0.197192665	normal	0.959992515	0.130348553	normal	0.497361625	0.203255165	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Protein disulfide-thiol oxidoreductase GN=ENOX2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ecto-NOX disulfide-thiol exchanger 2 isoform X3 [Canis lupus familiaris]
ENSG00000165678(GHITM)	--	135.977	4248	143.038	4574	143.745	4501	168.933	5369	155.562	4819	166.239	5202	0.953591052	0.306938444	normal	0.992429847	0.053833536	normal	0.984520849	0.20046669	normal	0.333454191	0.186765812	normal	[R]	General function prediction only	--	--	--	[T]	Signal transduction mechanisms	Inhibitor of apoptosis-promoting Bax1;; Bax inhibitor 1 like	Growth hormone-inducible transmembrane protein (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: growth hormone-inducible transmembrane protein isoform 1 [Ceratotherium simum simum] 
ENSG00000165684(SNAPC4)	--	4.322337815	491	4.413737342	506	4.193541	486	5.749004	642	5.98406	669	4.649206	527	0.820254889	0.355043981	normal	0.77628328	0.380450544	normal	0.966383025	0.108231712	normal	0.1681546	0.287876999	normal	--	--	--	"K09453|0|hsa:6621|SNAPC4, PTFalpha, SNAP190; small nuclear RNA activating complex, polypeptide 4, 190kDa; K09453 snRNA-activating protein complex subunit 4 (A)"	--	[K]	Transcription	Myb-like DNA-binding domain;; Myb-like DNA-binding domain	snRNA-activating protein complex subunit 4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: snRNA-activating protein complex subunit 4 isoform X1 [Equus przewalskii]
ENSG00000165685(TMEM52B)	--	0.159143709	2	0	0	0.0473879	1	0.047712981	2	0.046562062	1	0.283759	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane 52	Transmembrane protein 52B (Precursor) GN=TMEM52B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 52B [Dasypus novemcinctus]
ENSG00000165688(PMPCA)	--	32.55699593	1406	30.58793038	1371	28.45676	1286	36.6548532	1622	36.65655516	1578	30.0063	1346	0.971613261	0.175166641	normal	0.969817823	0.181255598	normal	0.981588621	0.057430308	normal	0.496045113	0.140211987	normal	[R]	General function prediction only	--	K01412|0|ptr:464862|PMPCA; peptidase (mitochondrial processing) alpha (EC:3.4.24.64); K01412 mitochondrial-processing peptidase subunit alpha [EC:3.4.24.64] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Insulinase (Peptidase family M16);; Peptidase M16 inactive domain	Mitochondrial-processing peptidase subunit alpha (Precursor) GN=PMPCA OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial-processing peptidase subunit alpha [Vicugna pacos]
ENSG00000165689(SDCCAG3)	--	26.6735138	1054	21.52257326	907	23.851617	975	29.011252	1162	29.06548341	1190	25.2720945	1047	0.975976369	0.109750536	normal	0.805673673	0.369820769	normal	0.976221426	0.094354623	normal	0.334319554	0.189822688	normal	--	--	--	--	--	--	--	--	Serologically defined colon cancer antigen 3 GN=SDCCAG3 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: serologically defined colon cancer antigen 3 homolog isoform X1 [Canis lupus familiaris]
ENSG00000165695(AK8)	--	0.69968	29	0.641944	27	0.885192	37	0.359629	15	0.514263	21	0.61848	26	0.915403396	-0.913506388	normal	0.980628198	-0.361009835	normal	0.964987401	-0.493143482	normal	0.394822885	-0.603976425	normal	[F]	Nucleotide transport and metabolism	--	"K00939|0|hsa:158067|AK8, AK_8, C9orf98, DDX31; adenylate kinase 8 (EC:2.7.4.3 2.7.4.6); K00939 adenylate kinase [EC:2.7.4.3] (A)"	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	"Adenylate kinase;; AAA domain;; AAA domain;; AAA domain;; ATPase family associated with various cellular activities (AAA);; Adenylate kinase, active site lid;; Shikimate kinase;; AAA domain (dynein-related subfamily)"	Adenylate kinase 8 GN=AK8 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: adenylate kinase 8 [Orycteropus afer afer]
ENSG00000165698(SPACA9)	--	5.001897	189	2.988239374	120	3.74552962	143	2.78216703	93	2.49132628	97	3.54028481	140	0.001438402	-1.041581614	down	0.929776579	-0.323855383	normal	0.967706103	-0.038468593	normal	0.257224784	-0.473864991	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4561)	Uncharacterized protein C9orf9 GN=C9orf9 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf9 homolog isoform X1 [Camelus bactrianus] 
ENSG00000165699(TSC1)	--	6.69960685	942	9.017294959	1215	5.613481097	1019	5.582767856	884	7.312125127	1073	8.585672693	1335	0.971990235	-0.122306971	normal	0.960645058	-0.200467074	normal	0.77778459	0.38089894	normal	0.95613985	0.031652882	normal	--	--	--	"K07206|0|hsa:7248|TSC1, LAM, TSC; tuberous sclerosis 1; K07206 tuberous sclerosis 1 (A)"	mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Choline metabolism in cancer (ko05231)	--	--	Hamartin protein	Hamartin GN=TSC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: hamartin isoform 4 [Dasypus novemcinctus]
ENSG00000165704(HPRT1)	--	81.5717	1551	77.8042	1478	85.2627	1595	98.1583	1890	74.564	1412	67.7249	1284	0.950173817	0.254126947	normal	0.980750589	-0.087241399	normal	0.892733393	-0.320862894	normal	0.93594728	-0.034255018	normal	[F]	Nucleotide transport and metabolism	Biological Process: nucleoside metabolic process (GO:0009116);; 	K00760|9.62269e-159|pon:100447935|HPRT1; hypoxanthine phosphoribosyltransferase 1; K00760 hypoxanthine phosphoribosyltransferase [EC:2.4.2.8] (A)	Purine metabolism (ko00230);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Phosphoribosyl transferase domain	Hypoxanthine-guanine phosphoribosyltransferase GN=HPRT1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: hypoxanthine-guanine phosphoribosyltransferase [Orycteropus afer afer]
ENSG00000165714(BORCS5)	--	9.145391	279	8.793046736	247	3.611384081	223	5.601983663	207	6.326005	230	5.296253	218	0.683165936	-0.45852286	normal	0.959319477	-0.123519804	normal	0.966363157	-0.040727662	normal	0.520456388	-0.214721355	normal	--	--	--	--	--	[S]	Function unknown	Tumour suppressor protein	Loss of heterozygosity 12 chromosomal region 1 protein GN=LOH12CR1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: loss of heterozygosity 12 chromosomal region 1 protein [Ceratotherium simum simum]
ENSG00000165716(FAM69B)	--	18.9104	717	11.24627	464	14.55012	580	12.05485	429	17.95439	670	12.2486	478	0.002399516	-0.769670206	normal	0.369535333	0.507226919	normal	0.903515844	-0.286509477	normal	0.725058255	-0.179848647	normal	--	--	--	--	--	--	--	"Protein-kinase domain of FAM69;; N-term cysteine-rich ER, FAM69"	Protein FAM69B GN=FAM69B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM69B [Camelus bactrianus]
ENSG00000165724(ZMYND19)	--	19.79149002	496	21.85529555	570	21.880431	574	24.92884033	632	25.08216873	626	19.466651	491	0.872871918	0.317878114	normal	0.966920404	0.113486801	normal	0.936226256	-0.232954831	normal	0.814059135	0.071071633	normal	--	--	--	--	--	--	--	MYND finger;; HNH endonuclease	Zinc finger MYND domain-containing protein 19 GN=ZMYND19 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger MYND domain-containing protein 19 [Oryctolagus cuniculus]
ENSG00000165730(STOX1)	--	0.644974842	46	0.730935209	42	0.600970548	42	0.380921033	27	0.517363403	37	0.502393538	36	0.866270672	-0.765731832	normal	0.977462588	-0.196737589	normal	0.977912253	-0.222039843	normal	0.563343191	-0.398852587	normal	--	--	--	--	--	--	--	Winged helix Storkhead-box1 domain	Storkhead-box protein 1 GN=STOX1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: storkhead-box protein 1 isoform X1 [Lipotes vexillifer]
ENSG00000165731(RET)	--	0.204298326	5	0.071744995	6	0.137376404	7	0.060598982	6	0.073595763	5	0.239847908	20	--	--	--	--	--	--	0.884359527	1.330278725	normal	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K05126|0|ggo:101141559|RET; proto-oncogene tyrosine-protein kinase receptor Ret; K05126 proto-oncogene tyrosine-protein kinase Ret [EC:2.7.10.1] (A)	Endocytosis (ko04144);; Pathways in cancer (ko05200);; Thyroid cancer (ko05216);; Central carbon metabolism in cancer (ko05230)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Cadherin domain	Extracellular cell-membrane anchored RET cadherin 120 kDa fragment (Precursor) GN=RET OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: proto-oncogene tyrosine-protein kinase receptor Ret [Equus przewalskii]
ENSG00000165732(DDX21)	--	63.746756	5663	66.645122	5946	63.85543	5608	64.790844	5799	72.070964	6374	58.082477	5166	0.994116261	0.003404432	normal	0.993460683	0.078833631	normal	0.991328209	-0.12669454	normal	0.975714352	-0.011327178	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Molecular Function: hydrolase activity (GO:0016787);; 	K16911|0|pps:100995398|DDX21; DEAD (Asp-Glu-Ala-Asp) box helicase 21; K16911 ATP-dependent RNA helicase DDX21 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; GUCT (NUC152) domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Nucleolar RNA helicase 2 GN=DDX21 OS=Homo sapiens (Human) PE=1 SV=5	A	RNA processing and modification	PREDICTED: nucleolar RNA helicase 2 isoform X2 [Leptonychotes weddellii]
ENSG00000165733(BMS1)	--	12.1162247	1870	11.87782299	1844	12.492407	1908	15.91503006	2469	15.7337818	2406	12.984937	1991	0.83880845	0.369791169	normal	0.858475022	0.362110768	normal	0.985895301	0.053099405	normal	0.112364282	0.266653437	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: ribosome biogenesis (GO:0042254);; 	"K14569|0|hsa:9790|BMS1, ACC, BMS1L; BMS1 ribosome biogenesis factor; K14569 ribosome biogenesis protein BMS1 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[J]	"Translation, ribosomal structure and biogenesis"	Protein of unknown function (DUF663);; AARP2CN (NUC121) domain;; Elongation factor Tu GTP binding domain	Ribosome biogenesis protein BMS1 homolog GN=BMS1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosome biogenesis protein BMS1 homolog [Camelus ferus]
ENSG00000165752(STK32C)	--	39.6437721	759	27.28078892	596	28.85751105	716	22.89813831	548	26.15029935	569	22.86377638	531	0.360886238	-0.499560214	normal	0.969181016	-0.088081468	normal	0.601921231	-0.438459653	normal	0.065631326	-0.35071434	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08793|0|hsa:282974|STK32C, PKE, YANK3; serine/threonine kinase 32C (EC:2.7.11.1); K08793 serine/threonine kinase 32 [EC:2.7.11.1] (A)"	--	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase 32C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 32C [Pteropus alecto]
ENSG00000165757(KIAA1462)	--	2.834937	538	1.85858892	352	2.66242683	502	8.994846697	1702	7.59703478	1434	5.69406728	1081	0	1.627965969	up	0	2.000363963	up	5.52E-08	1.09601131	up	1.46E-06	1.576841803	up	--	--	Cellular Component: cell-cell junction (GO:0005911);; 	--	--	--	--	Junctional protein associated with coronary artery disease	Junctional protein associated with coronary artery disease GN=KIAA1462 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: junctional protein associated with coronary artery disease [Galeopterus variegatus] 
ENSG00000165775(FUNDC2)	--	5.9647248	597	6.211982985	628	5.6918542	564	7.2341572	730	7.6402699	761	8.3561445	837	0.925105914	0.258730317	normal	0.92839286	0.255146472	normal	0.158068976	0.560000674	normal	0.050226843	0.359003478	normal	--	--	--	--	--	[S]	Function unknown	FUN14 family	FUN14 domain-containing protein 2 GN=FUNDC2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: FUN14 domain-containing protein 2 [Equus caballus] 
ENSG00000165782(TMEM55B)	--	28.978292	805	28.553596	910	25.13094658	794	21.66229	652	24.30952	649	30.0845	940	0.853281362	-0.334238674	normal	0.334381654	-0.508069673	normal	0.942909889	0.234818806	normal	0.579973276	-0.183236922	normal	--	--	"Molecular Function: phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity (GO:0034597);; Biological Process: phosphatidylinositol dephosphorylation (GO:0046856);; "	"K13084|3.4946e-162|pale:102898278|TMEM55B; transmembrane protein 55B; K13084 phosphatidylinositol-4,5-bisphosphate 4-phosphatase [EC:3.1.3.78] (A)"	--	[R]	General function prediction only	Transmembrane protein 55A	"Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase GN=TMEM55B OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1 [Vicugna pacos] "
ENSG00000165792(METTL17)	--	26.87643032	742	25.68243664	708	29.72467431	782	28.13655133	776	31.58527897	873	32.36046629	866	0.975861098	0.033736892	normal	0.914458672	0.280265787	normal	0.968438072	0.138652079	normal	0.505560681	0.151542366	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: translation (GO:0006412);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial small ribosomal subunit Rsm22;; Methyltransferase domain	"Methyltransferase-like protein 17, mitochondrial (Precursor) GN=METTL17 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: methyltransferase-like protein 17, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000165794(SLC39A2)	--	0	0	0.115648951	2	0	0	0	0	0	0	0.054121927	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14709|1.66992e-162|ptr:465210|SLC39A2; solute carrier family 39 (zinc transporter), member 2; K14709 solute carrier family 39 (zinc transporter), member 1/2/3 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP2 GN=SLC39A2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP2 [Ceratotherium simum simum]
ENSG00000165795(NDRG2)	--	4.5885906	158	4.316902723	105	4.518129982	125	1.7402285	56	4.49623584	117	2.663275186	70	1.84E-06	-1.501609672	down	0.963860369	0.132879028	normal	0.160889555	-0.831168663	normal	0.133022006	-0.69542918	normal	--	--	--	--	--	[S]	Function unknown	Ndr family;; Alpha/beta hydrolase family	Protein NDRG2 GN=NDRG2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein NDRG2 isoform X1 [Orycteropus afer afer] 
ENSG00000165799(RNASE7)	--	0	0	0	0	0	0	0.038955	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K01172|1.76448e-103|hsa:84659|RNASE7; ribonuclease, RNase A family, 7; K01172 ribonuclease 6/7/8 [EC:3.1.27.-] (A)"	--	--	--	Pancreatic ribonuclease	Ribonuclease 7 (Precursor) GN=RNASE7 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ribonuclease 7-like [Eptesicus fuscus]
ENSG00000165801(ARHGEF40)	--	5.15743	677	4.04123	542	4.87279	656	6.16733	807	6.998246	892	3.7409366	485	0.945185421	0.222118425	normal	0.012368772	0.695796298	normal	0.593521777	-0.442810632	normal	0.698446637	0.197892395	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Rho guanine nucleotide exchange factor 40 GN=ARHGEF40 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 40 [Ceratotherium simum simum]
ENSG00000165802(NSMF)	--	15.16165591	1088	13.68602484	980	16.0560923	1144	16.09562322	1135	14.92918961	1070	14.50642653	1012	0.980437575	0.030139806	normal	0.974957616	0.105175229	normal	0.963805379	-0.184909137	normal	0.955958996	-0.019087621	normal	--	--	--	--	--	--	--	--	NMDA receptor synaptonuclear signaling and neuronal migration factor GN=NSMF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: uncharacterized protein LOC102742938, partial [Leptonychotes weddellii]"
ENSG00000165804(ZNF219)	--	25.18320409	948	25.00741914	1145	21.754577	1088	17.86976378	861	18.70039483	825	26.66340824	1072	0.964209251	-0.169417811	normal	0.382301613	-0.493536468	normal	0.980183611	-0.02962361	normal	0.290252958	-0.226386888	normal	--	--	--	--	--	--	--	--	Transmembrane protein 253 GN=TMEM253 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein TREES_T100013498 [Tupaia chinensis]
ENSG00000165805(C12orf50)	--	0.101660528	3	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	Uncharacterized protein C12orf50 GN=C12orf50 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C12orf50 homolog [Ursus maritimus]
ENSG00000165806(CASP7)	--	11.03888528	506	11.17273428	506	13.1282465	608	17.1661828	770	17.43442356	726	17.32924396	710	0.133949514	0.573467955	normal	0.394066122	0.498156495	normal	0.94630975	0.214961022	normal	0.018741163	0.42433367	normal	--	--	--	"K04397|0|mcf:102127213|CASP7; caspase 7, apoptosis-related cysteine peptidase; K04397 caspase 7 [EC:3.4.22.60] (A)"	Apoptosis (ko04210);; TNF signaling pathway (ko04668);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Pertussis (ko05133);; Legionellosis (ko05134)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain	Caspase-7 subunit p11 (Precursor) GN=CASP7 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	"PREDICTED: LOW QUALITY PROTEIN: caspase 7, apoptosis-related cysteine peptidase [Bubalus bubalis]"
ENSG00000165807(PPP1R36)	--	0.041402004	1	0.08153414	2	0.247917672	1	0	0	0.0396826	0	0.123431015	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: negative regulation of phosphatase activity (GO:0010923);; Molecular Function: phosphatase binding (GO:0019902);; 	"K17575|0|hsa:145376|PPP1R36, C14orf50; protein phosphatase 1, regulatory subunit 36; K17575 protein phosphatase 1 regulatory subunit 36 (A)"	--	--	--	Protein phosphatase 1 inhibitor	Protein phosphatase 1 regulatory subunit 36 GN=PPP1R36 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 36 [Odobenus rosmarus divergens]
ENSG00000165810(BTNL9)	--	0.9156039	44	0.355526464	20	0.3205339	17	0.399482654	24	0.477051882	24	0.5484911	33	0.816718996	-0.8638479	normal	0.98548233	0.225992947	normal	0.896206667	0.890855799	normal	1	-0.02105675	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06712|0|hsa:153579|BTNL9, BTN3, BTN8, VDLS1900; butyrophilin-like 9; K06712 butyrophilin (A)"	--	--	--	SPRY domain;; SPRY-associated domain;; Immunoglobulin V-set domain	Butyrophilin-like protein 9 (Precursor) GN=BTNL9 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: butyrophilin-like protein 9 [Equus przewalskii]
ENSG00000165813(CCDC186)	--	4.538895462	531	4.3383087	552	4.465251966	554	4.84366725	618	4.37332478	569	4.9719775	611	0.953033581	0.187559323	normal	0.972064106	0.022273725	normal	0.964761763	0.132650042	normal	0.672645406	0.114113576	normal	--	--	--	--	--	[S]	Function unknown	--	Coiled-coil domain-containing protein 186 GN=CCDC186 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C10orf118 homolog [Balaenoptera acutorostrata scammoni]
ENSG00000165816(VWA2)	--	0	0	0	0	0	0	0.0190696	1	0.038170246	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[W]	Extracellular structures	von Willebrand factor type A domain;; von Willebrand factor type A domain;; EGF-like domain;; EGF-like domain	von Willebrand factor A domain-containing protein 2 (Precursor) GN=VWA2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: von Willebrand factor A domain-containing protein 2 [Galeopterus variegatus]
ENSG00000165819(METTL3)	--	23.271	894	29.09669693	1098	26.5306	1026	26.0762	1008	21.8828	836	20.6723	795	0.969870834	0.142086584	normal	0.68802828	-0.414073942	normal	0.781593617	-0.375664592	normal	0.269834571	-0.215552342	normal	--	--	Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: methyltransferase activity (GO:0008168);; 	K05925|0|mcf:101867229|hypothetical protein; K05925 mRNA (2'-O-methyladenosine-N6-)-methyltransferase [EC:2.1.1.62] (A)	--	[A]	RNA processing and modification	MT-A70	N6-adenosine-methyltransferase 70 kDa subunit GN=METTL3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: N6-adenosine-methyltransferase 70 kDa subunit [Tupaia chinensis]
ENSG00000165821(SALL2)	--	4.732918949	433	3.672144301	337	4.270529803	439	1.809801792	126	1.898875739	195	0.627539306	65	9.99E-16	-1.799159381	down	0.008903239	-0.805884925	normal	0	-2.735672399	down	6.49E-08	-1.669100353	down	[R]	General function prediction only	--	--	--	[K]	Transcription	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	Sal-like protein 2 GN=SALL2 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: sal-like protein 2 isoform X1 [Sus scrofa]
ENSG00000165828(PRAP1)	--	20.879302	575	19.941431	563	20.33148	586	17.57735	489	18.01762	496	16.9728702	472	0.919372152	-0.263794362	normal	0.94685454	-0.203638119	normal	0.871608529	-0.319484691	normal	0.224890421	-0.263977214	normal	--	--	--	--	--	--	--	"Proline-rich acidic protein 1, pregnancy-specific uterine"	Proline-rich acidic protein 1 (Precursor) GN=PRAP1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: proline-rich acidic protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000165832(TRUB1)	--	15.7202	755	16.9328	806	17.5651	822	17.6326	851	17.6925	848	19.0697	915	0.967479827	0.141578745	normal	0.975743749	0.051763179	normal	0.96803481	0.146087058	normal	0.640655296	0.11258007	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: RNA processing (GO:0006396);; 	"K03177|0|hsa:142940|TRUB1, PUS4; TruB pseudouridine (psi) synthase family member 1; K03177 tRNA pseudouridine55 synthase [EC:5.4.99.25] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	TruB family pseudouridylate synthase (N terminal domain)	Probable tRNA pseudouridine synthase 1 GN=TRUB1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: probable tRNA pseudouridine synthase 1 [Condylura cristata]
ENSG00000165861(ZFYVE1)	--	5.15839508	428	6.334521117	500	5.832145256	450	5.6910746	462	5.890392057	447	9.458310127	783	0.967715354	0.079176196	normal	0.951761022	-0.182495668	normal	0.001347379	0.788761227	normal	0.628904125	0.276464981	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K17603|0|pon:100171453|ZFYVE1; zinc finger, FYVE domain containing 1; K17603 zinc finger FYVE domain-containing protein 1 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"FYVE zinc finger;; Guanylate-binding protein, N-terminal domain"	Zinc finger FYVE domain-containing protein 1 GN=PP10436 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: zinc finger FYVE domain-containing protein 1-like isoform X1 [Tupaia chinensis]
ENSG00000165868(HSPA12A)	--	8.79502408	928	8.335459762	849	7.753819	830	16.020231	1662	16.59402124	1697	12.73531226	1309	0.000275346	0.808877569	normal	1.96E-06	0.976469698	normal	0.022169094	0.648042274	normal	8.68E-07	0.818502345	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein	Heat shock 70 kDa protein 12A GN=HSPA12A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 12A [Equus przewalskii]
ENSG00000165879(FRAT1)	--	1.01291	42	1.38803	60	1.13332	49	1.33172	56	0.907157	38	2.20699	93	0.961004393	0.372375681	normal	0.853716443	-0.659326399	normal	0.236060164	0.89576653	normal	0.739936328	0.288680462	normal	--	--	--	K03069|4.43912e-133|hsa:10023|FRAT1; frequently rearranged in advanced T-cell lymphomas 1; K03069 frequently rearranged in advanced T-cell lymphomas 1 (A)	Wnt signaling pathway (ko04310)	--	--	Glycogen synthase kinase-3 binding	Proto-oncogene FRAT1 GN=FRAT1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: proto-oncogene FRAT1 [Odobenus rosmarus divergens]
ENSG00000165886(UBTD1)	--	11.1386	366	12.0796	405	11.4249	391	12.3903	410	11.3222	371	9.40896	313	0.960719849	0.132422605	normal	0.957540309	-0.147354157	normal	0.869551261	-0.32787697	normal	0.736046919	-0.108977636	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: ubiquitin binding (GO:0043130);; 	--	--	[S]	Function unknown	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like	Ubiquitin domain-containing protein 1 GN=UBTD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin domain-containing protein 1 [Galeopterus variegatus]
ENSG00000165887(ANKRD2)	--	2.5047269	55	2.788042664	68	2.5770273	81	3.966254	112	3.6474559	91	4.470219345	124	0.060734289	0.975697297	normal	0.926254505	0.391358609	normal	0.669669512	0.596982213	normal	0.099569136	0.660223153	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 2 GN=ANKRD2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 2 [Canis lupus familiaris]
ENSG00000165891(E2F7)	--	4.303157449	387	5.670525	530	5.224118182	499	5.431176	490	4.863700004	497	5.52876	570	0.884117642	0.308525317	normal	0.965100822	-0.113837556	normal	0.953591811	0.183111083	normal	0.683532013	0.116292357	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09391|0|hsa:144455|E2F7; E2F transcription factor 7; K09391 transcription factor E2F7/8 (A)	--	[K]	Transcription	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F7 GN=E2F7 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor E2F7 [Galeopterus variegatus]
ENSG00000165895(ARHGAP42)	--	3.482683727	337	2.77109321	349	3.250482508	401	3.635355216	454	3.428895809	412	4.6088849	547	0.753518838	0.397544985	normal	0.939710472	0.217124022	normal	0.62756692	0.438226677	normal	0.105576068	0.358014216	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain;; Variant SH3 domain;; SH3 domain	Rho GTPase-activating protein 42 GN=ARHGAP42 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: Rho GTPase activating protein 42 [Equus caballus]
ENSG00000165898(ISCA2)	--	13.890946	430	13.48459	447	21.18548	517	16.05020881	491	14.93031	435	16.060143	478	0.957255466	0.160018772	normal	0.968140645	-0.060478565	normal	0.964635749	-0.121076669	normal	0.983948554	-0.010715033	normal	[S]	Function unknown	--	--	--	[CU]	"Energy production and conversion;; Intracellular trafficking, secretion, and vesicular transport"	Iron-sulphur cluster biosynthesis	"Iron-sulfur cluster assembly 2 homolog, mitochondrial (Precursor) GN=ISCA2 OS=Homo sapiens (Human) PE=1 SV=2"	CU	"Energy production and conversion;; Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: iron-sulfur cluster assembly 2 homolog, mitochondrial [Ceratotherium simum simum]"
ENSG00000165899(OTOGL)	--	0.035305148	2	0	0	0	0	0	0	0	0	0.017443639	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: L-arabinose metabolic process (GO:0046373);; Molecular Function: alpha-L-arabinofuranosidase activity (GO:0046556);; 	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type D domain;; C8 domain;; Trypsin Inhibitor like cysteine rich domain;; Alpha-L-arabinofuranosidase B (ABFB)	Otogelin-like protein (Precursor) GN=OTOGL OS=Homo sapiens (Human) PE=2 SV=5	VW	Defense mechanisms;; Extracellular structures	PREDICTED: otogelin-like protein [Balaenoptera acutorostrata scammoni]
ENSG00000165905(LARGE2)	--	2.869042711	121	2.461175096	87	2.1879129	96	1.042754196	27	1.442742628	62	0.385640319	17	1.79E-09	-2.132141206	down	0.879658614	-0.499830438	normal	2.99E-09	-2.404989298	down	0.00042359	-1.541563859	down	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K09668|0|hsa:120071|GYLTL1B, LARGE2; glycosyltransferase-like 1B; K09668 glycosyltransferase-like protein LARGE (A)"	--	[G]	Carbohydrate transport and metabolism	Glycosyl-transferase for dystroglycan;; Glycosyl transferase family 8	"Beta-1,3-glucuronyltransferase LARGE2 {ECO:0000305} GN=GYLTL1B OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: glycosyltransferase-like protein LARGE2 [Ceratotherium simum simum]
ENSG00000165912(PACSIN3)	--	20.4081528	706	18.66946963	622	19.44843969	709	17.22815505	602	18.73207488	625	13.34072591	443	0.924032818	-0.260123101	normal	0.973396905	-0.014449901	normal	0.017237469	-0.684904813	normal	0.124549735	-0.308419185	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TUZ]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	"Fes/CIP4, and EFC/F-BAR homology domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain"	Protein kinase C and casein kinase substrate in neurons protein 3 GN=PACSIN3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein kinase C and casein kinase substrate in neurons protein 3 [Felis catus] 
ENSG00000165914(TTC7B)	--	19.65026432	598	19.99785514	552	21.27009289	603	16.21085074	505	18.20958765	474	14.78199854	462	0.912859657	-0.273927364	normal	0.931947118	-0.240495938	normal	0.748812952	-0.391431624	normal	0.146296949	-0.304121354	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	"Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Tetratricopeptide repeat protein 7B GN=TTC7B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tetratricopeptide repeat protein 7B [Ochotona princeps]
ENSG00000165915(SLC39A13)	--	19.62646185	854	18.69323198	784	21.68490877	934	25.77378655	1122	24.89320255	1029	23.49866827	1023	0.811799373	0.362362194	normal	0.800107259	0.370265747	normal	0.972979326	0.122830159	normal	0.115419089	0.28217772	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14719|0|hsa:91252|SLC39A13; solute carrier family 39 (zinc transporter), member 13; K14719 solute carrier family 39 (zinc transporter), member 13 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP13 GN=SLC39A13 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP13 isoform X1 [Galeopterus variegatus]
ENSG00000165916(PSMC3)	--	71.410836	2221	72.7619784	2333	76.481591	2426	77.06886028	2378	74.957126	2266	56.65240525	1730	0.986982805	0.06766182	normal	0.986812977	-0.063423286	normal	0.371909223	-0.495731211	normal	0.475324614	-0.15299059	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	"K03065|0|hsa:5702|PSMC3, TBP1; proteasome (prosome, macropain) 26S subunit, ATPase, 3; K03065 26S proteasome regulatory subunit T5 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily);; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (Cdc48 subfamily)	26S protease regulatory subunit 6A GN=PSMC3 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S protease regulatory subunit 6A [Galeopterus variegatus]
ENSG00000165917(RAPSN)	--	0.042749619	1	0.082203874	2	0.115475925	2	0.037927175	1	0.083132199	1	0.126520625	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: synaptic transmission (GO:0007268);; Molecular Function: acetylcholine receptor binding (GO:0033130);; Molecular Function: protein anchor (GO:0043495);; 	--	--	[W]	Extracellular structures	Rapsyn N-terminal myristoylation and linker region;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Ring finger domain	43 kDa receptor-associated protein of the synapse GN=RAPSN OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: 43 kDa receptor-associated protein of the synapse isoform X1 [Galeopterus variegatus]
ENSG00000165923(AGBL2)	--	1.107030335	52	2.013735861	51	3.126655003	69	1.157808501	33	1.009013654	33	1.069103432	32	0.890824149	-0.66210536	normal	0.904991456	-0.626193547	normal	0.171839026	-1.08119995	normal	0.106874436	-0.832275388	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallocarboxypeptidase activity (GO:0004181);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[E]	Amino acid transport and metabolism	Zinc carboxypeptidase;; Putative binding domain	Cytosolic carboxypeptidase 2 GN=AGBL2 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: cytosolic carboxypeptidase 2 [Trichechus manatus latirostris]
ENSG00000165934(CPSF2)	--	17.32931711	2048	16.78290027	2114	17.47009697	2165	17.5118871	2167	16.12694303	2231	16.51393705	1950	0.986694002	0.05061426	normal	0.986493491	0.056249408	normal	0.978906642	-0.159067208	normal	0.959389613	-0.016612127	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K14402|0|ptr:738846|CPSF2; cleavage and polyadenylation specific factor 2, 100kDa; K14402 cleavage and polyadenylation specificity factor subunit 2 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Cleavage and polyadenylation factor 2 C-terminal;; Beta-Casp domain;; RNA-metabolising metallo-beta-lactamase;; Metallo-beta-lactamase superfamily	Cleavage and polyadenylation specificity factor subunit 2 GN=CPSF2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	cleavage and polyadenylation specificity factor subunit 2 [Bos taurus] 
ENSG00000165935(SMCO2)	--	0.0499629	1	0.05024483	1	0.04975872	0	0.199527792	4	0.049198592	0	0.1000182	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMCO5 family	Single-pass membrane and coiled-coil domain-containing protein 2 GN=SMCO2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C12orf70 homolog [Ceratotherium simum simum]
ENSG00000165943(MOAP1)	--	10.43441	430	10.85547	460	11.19737	468	11.647484	486	11.27494	462	11.71199	485	0.959982535	0.145298856	normal	0.970124648	-0.015117975	normal	0.970543837	0.043048125	normal	0.870951568	0.056416701	normal	--	--	--	--	--	--	--	PNMA	Modulator of apoptosis 1 GN=MOAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: modulator of apoptosis 1 [Felis catus]
ENSG00000165948(IFI27L1)	--	14.09704877	118	9.8940432	110	16.32428314	154	8.931664277	85	8.154788	80	10.93375131	110	0.827968122	-0.496431045	normal	0.859415536	-0.473195736	normal	0.776506444	-0.488020788	normal	0.201431361	-0.494011984	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced 6-16 family	Interferon alpha-inducible protein 27-like protein 1 GN=IFI27L1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	--
ENSG00000165949(IFI27)	--	1.628227208	10	1.213277698	11	0.573799179	1	0.442203118	5	0.330188991	3	0.475577564	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced 6-16 family	"Interferon alpha-inducible protein 27, mitochondrial (Precursor) GN=IFI27 OS=Homo sapiens (Human) PE=2 SV=3"	S	Function unknown	--
ENSG00000165959(CLMN)	--	9.172287176	1896	7.031032213	1598	8.763616721	1741	5.532988611	1113	4.629351158	990	4.814058874	1078	0.000319162	-0.798482313	normal	0.005264227	-0.711329606	normal	0.005524959	-0.6990712	normal	1.24E-07	-0.74001443	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Calponin homology (CH) domain;; CAMSAP CH domain	Calmin GN=CLMN OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: calmin [Galeopterus variegatus]
ENSG00000165966(PDZRN4)	--	0	0	0	0	0	0	0.02750601	2	0	0	0.013667799	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K15682|0|hsa:29951|PDZRN4, LNX4, SAMCAP3L; PDZ domain containing ring finger 4; K15682 ligand of Numb protein X 3/4 (A)"	--	[S]	Function unknown	"PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	PDZ domain-containing RING finger protein 4 GN=PDZRN4 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: PDZ domain-containing RING finger protein 4-like isoform X1 [Elephantulus edwardii]
ENSG00000165972(CCDC38)	--	0.189656	7	0.519371981	20	0.107852	3	0.0268093	1	0.0523693	1	0.020252313	1	--	--	--	0.021529486	-3.112324918	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4200)	Coiled-coil domain-containing protein 38 GN=CCDC38 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 38 [Panthera tigris altaica]
ENSG00000165983(PTER)	--	10.76987854	537	8.360995235	427	7.928824656	413	10.33482261	543	10.09258097	521	8.623176881	421	0.97242811	-0.014760158	normal	0.918254685	0.264770646	normal	0.969982371	0.019316951	normal	0.78854852	0.086817049	normal	[R]	General function prediction only	"Molecular Function: zinc ion binding (GO:0008270);; Biological Process: catabolic process (GO:0009056);; Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	"K07048|0|hsa:9317|PTER, HPHRP, RPR-1; phosphotriesterase related; K07048 phosphotriesterase-related protein (A)"	--	--	--	Phosphotriesterase family;; TatD related DNase	Phosphotriesterase-related protein GN=PTER OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: phosphotriesterase-related protein isoform X1 [Galeopterus variegatus]
ENSG00000165985(C1QL3)	--	0.431805	16	0.899763	34	0.542519	20	0.66759	25	1.11516	41	0.396768	15	0.976546515	0.569029139	normal	0.976812754	0.238972355	normal	0.986152613	-0.38924126	normal	0.886955568	0.18809235	normal	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	Complement C1q-like protein 3 (Precursor) GN=C1QL3 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: complement C1q-like protein 3 [Erinaceus europaeus]
ENSG00000165995(CACNB2)	--	0.622068095	25	0.364006653	17	0.365398844	20	0.254661206	12	0.23657547	11	0.427646653	21	0.921041075	-0.999315099	normal	--	--	--	0.988474233	0.057830205	normal	0.554595163	-0.51426725	normal	--	--	Molecular Function: voltage-gated calcium channel activity (GO:0005245);; Cellular Component: voltage-gated calcium channel complex (GO:0005891);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04863|0|ptr:740138|CACNB2; calcium channel, voltage-dependent, beta 2 subunit; K04863 voltage-dependent calcium channel beta-2 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Guanylate kinase;; Voltage gated calcium channel subunit beta domain 4Aa N terminal	Voltage-dependent L-type calcium channel subunit beta-2 GN=CACNB2 OS=Homo sapiens (Human) PE=1 SV=3	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: voltage-dependent L-type calcium channel subunit beta-2 isoform X1 [Elephantulus edwardii]
ENSG00000165996(HACD1)	--	23.83240643	361	25.2067181	421	21.54028154	363	25.8095276	471	20.81084101	374	28.96941923	470	0.833601647	0.351582733	normal	0.947949884	-0.191478249	normal	0.816363726	0.363066973	normal	0.513064167	0.178249811	normal	--	--	--	"K10703|0|hsa:9200|PTPLA, CAP, HACD1; protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A (EC:4.2.1.134); K10703 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] (A)"	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[R]	General function prediction only	"Protein tyrosine phosphatase-like protein, PTPLA"	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 1 GN=PTPLA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 1 [Odobenus rosmarus divergens]
ENSG00000165997(ARL5B)	--	9.352098639	901	11.21103105	1070	8.678108	808	11.28058045	1101	12.879936	1245	10.65117247	1027	0.933860183	0.257984703	normal	0.961818012	0.196850269	normal	0.854501651	0.337156543	normal	0.205273087	0.257779768	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07950|5.61425e-131|umr:103664218|ARL5B; ADP-ribosylation factor-like 5B; K07950 ADP-ribosylation factor-like protein 5B (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Signal recognition particle receptor beta subunit;; Miro-like protein;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	ADP-ribosylation factor-like protein 5B GN=ARL5B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 5B isoform X1 [Equus caballus] 
ENSG00000166002(SMCO4)	--	10.93459845	125	11.53038974	129	13.39425936	134	11.87277478	162	9.671979963	122	12.32776538	154	0.909147964	0.339558885	normal	0.964693927	-0.100702315	normal	0.955189544	0.190400041	normal	0.749817961	0.153489845	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4519)	--	--	--	--
ENSG00000166004(CEP295)	--	3.5716106	550	4.59187	628	5.273907002	679	3.459928262	553	3.81865126	517	3.7835066	600	0.972516955	-0.022920548	normal	0.891765393	-0.301225935	normal	0.955001663	-0.186298809	normal	0.466156679	-0.173871738	normal	--	--	--	--	--	--	--	ALMS motif	Centrosomal protein of 295 kDa {ECO:0000312|HGNC:HGNC:29366} OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: centrosomal protein KIAA1731 homolog isoform X5 [Galeopterus variegatus]
ENSG00000166006(KCNC2)	--	0	0	0	0	0.042252487	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04888|0|pps:100974106|KCNC2; potassium voltage-gated channel, Shaw-related subfamily, member 2; K04888 potassium voltage-gated channel Shaw-related subfamily C member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily C member 2 GN=KCNC2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily C member 2 isoform X1 [Lipotes vexillifer]
ENSG00000166012(TAF1D)	--	12.25022	972	13.387864	868	12.98623	939	12.00028	1008	13.456236	1082	12.62369	950	0.979256648	0.021601627	normal	0.906766529	0.296044221	normal	0.978931668	0.008497308	normal	0.643252981	0.108256887	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Cellular Component: RNA polymerase transcription factor SL1 complex (GO:0005668);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15215|3.53774e-167|ptr:451484|TAF1D, JOSD3; TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa; K15215 TATA box-binding protein-associated factor RNA polymerase I subunit D (A)"	--	--	--	TATA box-binding protein-associated factor 1D	TATA box-binding protein-associated factor RNA polymerase I subunit D GN=TAF1D OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: TATA box-binding protein-associated factor RNA polymerase I subunit D [Odobenus rosmarus divergens]
ENSG00000166016(ABTB2)	--	14.4158	1383	16.3112	1589	13.9676	1374	12.3186	1180	11.9449	1141	14.7544	1424	0.939390268	-0.259534003	normal	0.362547521	-0.498684026	normal	0.982749133	0.043228961	normal	0.183844249	-0.235542273	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10521|0|hsa:25841|ABTB2, ABTB2A, BTBD22; ankyrin repeat and BTB (POZ) domain containing 2; K10521 ankyrin repeat and BTB/POZ domain-containing protein 2 (A)"	--	--	--	Ankyrin repeats (3 copies);; BTB/POZ domain;; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies)	Ankyrin repeat and BTB/POZ domain-containing protein 2 GN=ABTB2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and BTB/POZ domain-containing protein 2 [Trichechus manatus latirostris]
ENSG00000166024(R3HCC1L)	--	5.912351552	421	5.539626162	394	5.583600996	390	6.902210153	474	7.044065975	485	6.63026205	475	0.960707293	0.139753717	normal	0.90994076	0.277401431	normal	0.911679735	0.275193557	normal	0.348788579	0.229780773	normal	--	--	--	--	--	[S]	Function unknown	--	Coiled-coil domain-containing protein R3HCC1L GN=R3HCC1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: R3H and coiled-coil domain-containing protein 1-like [Ceratotherium simum simum]
ENSG00000166025(AMOTL1)	--	4.76491988	894	4.803971371	903	4.830308247	846	6.521035033	1211	6.871733	1160	4.780069648	893	0.701431195	0.406417764	normal	0.858480042	0.339397711	normal	0.976045959	0.069589979	normal	0.153254483	0.282327368	normal	--	--	--	K06104|0|ptr:451491|AMOTL1; angiomotin like 1; K06104 angiomotin like 1 (A)	Tight junction (ko04530)	--	--	Angiomotin C terminal	Angiomotin-like protein 1 GN=AMOTL1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: angiomotin-like protein 1 isoform X1 [Pteropus alecto]
ENSG00000166033(HTRA1)	--	33.09423062	1229	32.20586537	1211	28.4913129	1076	32.33937795	1203	38.75724067	1442	35.07204798	1307	0.98045226	-0.061602693	normal	0.954179662	0.230182048	normal	0.930024014	0.271942318	normal	0.478197495	0.147558506	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	K08784|0|pon:100437050|HTRA1; HtrA serine peptidase 1; K08784 HtrA serine peptidase 1 [EC:3.4.21.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Trypsin-like peptidase domain;; Trypsin;; PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Insulin-like growth factor binding protein;; Peptidase S46	Serine protease HTRA1 (Precursor) GN=HTRA1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: serine protease HTRA1-like [Sus scrofa]
ENSG00000166035(LIPC)	--	0.021249929	1	0	0	0	0	0	0	0.025635933	0	0.018462	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K01046|0|hsa:3990|LIPC, HDLCQ12, HL, HTGL, LIPH; lipase, hepatic (EC:3.1.1.3); K01046 triacylglycerol lipase [EC:3.1.1.3] (A)"	Glycerolipid metabolism (ko00561)	--	--	Lipase;; PLAT/LH2 domain	Hepatic triacylglycerol lipase (Precursor) GN=LIPC OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: hepatic triacylglycerol lipase [Loxodonta africana]
ENSG00000166037(CEP57)	--	10.9197788	541	12.34875185	655	12.26873336	633	11.15976944	619	9.021464725	504	12.61411038	670	0.959104338	0.163045442	normal	0.734813002	-0.398445682	normal	0.972306527	0.073493471	normal	0.877146756	-0.049656935	normal	--	--	Molecular Function: microtubule binding (GO:0008017);; Molecular Function: identical protein binding (GO:0042802);; Molecular Function: gamma-tubulin binding (GO:0043015);; 	"K16762|0|hsa:9702|CEP57, MVA2, PIG8, TSP57; centrosomal protein 57kDa; K16762 centrosomal protein CEP57 (A)"	--	--	--	Centrosome localisation domain of Cep57;; Centrosome microtubule-binding domain of Cep57	Centrosomal protein of 57 kDa GN=CEP57 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: centrosomal protein of 57 kDa isoform X1 [Leptonychotes weddellii]
ENSG00000166046(TCP11L2)	--	4.760384498	159	4.412403281	145	3.723224	114	3.430373543	111	2.70950042	97	5.440070856	185	0.666260858	-0.542982686	normal	0.595196408	-0.593797586	normal	0.245872965	0.683020797	normal	0.883493494	-0.109093661	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	T-complex protein 11	T-complex protein 11-like protein 2 GN=TCP11L2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: T-complex protein 11-like protein 2 [Ceratotherium simum simum]
ENSG00000166068(SPRED1)	--	8.043238	722	7.689915	751	7.698951348	668	7.980364024	702	7.681917958	666	8.055847515	655	0.973413574	-0.071206386	normal	0.953793162	-0.194301502	normal	0.974282917	-0.036561048	normal	0.691636075	-0.103375543	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	"K04703|0|ptr:467654|SPRED1; sprouty-related, EVH1 domain containing 1; K04703 sprouty-related, EVH1 domain-containing protein (A)"	Jak-STAT signaling pathway (ko04630)	[T]	Signal transduction mechanisms	Sprouty protein (Spry);; WH1 domain	"Sprouty-related, EVH1 domain-containing protein 1 GN=SPRED1 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: sprouty-related, EVH1 domain-containing protein 1 [Galeopterus variegatus]"
ENSG00000166073(GPR176)	--	4.62702093	357	4.800300352	359	5.254755056	399	3.042655752	226	2.330938156	184	4.68113703	362	0.055101481	-0.686684159	normal	0.000198624	-0.979827962	normal	0.95821343	-0.148100914	normal	0.117028191	-0.549957814	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08442|0|ggo:101135865|GPR176; probable G-protein coupled receptor 176 isoform 1; K08442 G protein-coupled receptor 176 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 176 GN=GPR176 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 176 [Condylura cristata]
ENSG00000166086(JAM3)	--	2.748275655	184	2.462149935	155	2.333234702	152	2.471855063	168	2.886063478	199	2.439764529	160	0.957191574	-0.160672033	normal	0.895721287	0.336172476	normal	0.966285454	0.065078005	normal	0.874611439	0.080701223	normal	--	--	--	K06785|0|ptr:451678|JAM3; junctional adhesion molecule 3; K06785 junctional adhesion molecule 3 (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670)	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain	Junctional adhesion molecule C (Precursor) GN=JAM3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: junctional adhesion molecule C [Trichechus manatus latirostris]
ENSG00000166105(GLB1L3)	--	0	0	0	0	0	0	0	0	0.0473158	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: beta-galactosidase activity (GO:0004565);; Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: beta-galactosidase complex (GO:0009341);; 	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 35;; Beta-galactosidase	Beta-galactosidase-1-like protein 3 GN=GLB1L3 OS=Homo sapiens (Human) PE=2 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: beta-galactosidase-1-like protein 3 [Panthera tigris altaica]
ENSG00000166106(ADAMTS15)	--	0.858747319	97	0.878461067	101	0.951486774	110	2.061394082	235	2.162588159	245	1.690847633	193	1.09E-05	1.232841125	up	7.18E-06	1.244659905	up	0.061972207	0.794455612	normal	3.68E-05	1.106171791	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K08629|0|hsa:170689|ADAMTS15; ADAM metallopeptidase with thrombospondin type 1 motif, 15; K08629 a disintegrin and metalloproteinase with thrombospondin motifs 15 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Reprolysin family propeptide;; Reprolysin (M12B) family zinc metalloprotease;; Thrombospondin type 1 domain;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 15 (Precursor) GN=ADAMTS15 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 15 [Galeopterus variegatus]
ENSG00000166123(GPT2)	--	7.610855101	556	10.75207647	611	8.282659092	620	11.1441615	851	12.45309859	756	17.6994359	1125	0.108879938	0.581933366	normal	0.907897358	0.285151784	normal	0.000136007	0.84973244	normal	0.036723356	0.592115895	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	K00814|0|ggo:101142979|GPT2; alanine aminotransferase 2 isoform 1; K00814 alanine transaminase [EC:2.6.1.2] (A)	"Alanine, aspartate and glutamate metabolism (ko00250);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Aminotransferase class I and II	Alanine aminotransferase 2 GN=GPT2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: alanine aminotransferase 2 isoform X1 [Mustela putorius furo] 
ENSG00000166126(AMN)	--	0.149038513	4	0.178864589	5	0.38653162	10	0.148147915	4	0.0357096	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18259|0|hsa:81693|AMN, PRO1028, amnionless; amnion associated transmembrane protein; K18259 protein amnionless (A)"	--	--	--	Amnionless	Protein amnionless (Precursor) GN=AMN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein amnionless [Orcinus orca]
ENSG00000166128(RAB8B)	--	16.124306	1032	13.05752528	869	15.5190527	1013	16.57390968	1117	16.71891	991	12.903641	861	0.977732752	0.083234827	normal	0.964670782	0.167828678	normal	0.940941546	-0.242447417	normal	0.988440292	0.005152435	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07902|1.24006e-149|ptr:453498|RAB8B; RAB8B, member RAS oncogene family; K07902 Ras-related protein Rab-8B (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Signal recognition particle receptor beta subunit;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-8B (Precursor) GN=RAB8B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-8B [Oryctolagus cuniculus]
ENSG00000166130(IKBIP)	--	40.92769	1595	44.22035	1829	41.47367	1705	50.60458	2155	42.91651	1712	45.2676	1918	0.745551729	0.402964158	normal	0.981099183	-0.116699173	normal	0.976761964	0.161404491	normal	0.442587717	0.151959403	normal	--	--	--	--	--	--	--	--	Inhibitor of nuclear factor kappa-B kinase-interacting protein GN=IKBIP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: inhibitor of nuclear factor kappa-B kinase-interacting protein isoform X1 [Physeter catodon]
ENSG00000166133(RPUSD2)	--	5.699053	221	6.631376	223	6.675246365	247	6.760475	247	7.91472	283	5.638699	224	0.959867693	0.128785244	normal	0.888567632	0.320399101	normal	0.95725286	-0.148349555	normal	0.791524454	0.104701108	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	--	--	[A]	RNA processing and modification	RNA pseudouridylate synthase	RNA pseudouridylate synthase domain-containing protein 2 GN=RPUSD2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: RNA pseudouridylate synthase domain-containing protein 2 isoform X1 [Lipotes vexillifer]
ENSG00000166135(HIF1AN)	--	9.417286977	1565	7.858984857	1591	9.23949821	1709	8.554161965	1681	8.340697204	1647	10.22231818	1745	0.983251347	0.072256352	normal	0.984217942	0.02845358	normal	0.985364832	0.021764138	normal	0.887313641	0.03945221	normal	--	--	--	"K18055|0|mcc:710425|HIF1AN; hypoxia inducible factor 1, alpha subunit inhibitor; K18055 hypoxia-inducible factor 1-alpha inhibitor (HIF hydroxylase) [EC:1.14.11.30] (A)"	--	[BT]	Chromatin structure and dynamics;; Signal transduction mechanisms	Cupin-like domain;; Cupin superfamily protein	Hypoxia-inducible factor 1-alpha inhibitor GN=HIF1AN OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: hypoxia-inducible factor 1-alpha inhibitor [Trichechus manatus latirostris]
ENSG00000166136(NDUFB8)	--	129.820685	1190	132.18436	1253	138.93495	1337	147.253656	1507	135.67672	1239	137.42238	1299	0.902303166	0.309529779	normal	0.981155518	-0.037591159	normal	0.981886703	-0.04983229	normal	0.753427657	0.076190467	normal	--	--	Molecular Function: NADH dehydrogenase activity (GO:0003954);; Cellular Component: mitochondrion (GO:0005739);; Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; 	"K03964|5.24788e-136|ptr:744716|NDUFB8; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa; K03964 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 8 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8)	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial (Precursor) GN=NDUFB8 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial [Equus caballus] "
ENSG00000166140(ZFYVE19)	--	9.55232059	362	7.585058855	259	12.52623463	350	12.8591619	427	14.69097894	498	14.79412984	481	0.944046367	0.206606041	normal	0.000243722	0.917836807	normal	0.611119798	0.448729947	normal	0.012592067	0.513552777	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	FYVE zinc finger	Abscission/NoCut checkpoint regulator GN=ZFYVE19 OS=Homo sapiens (Human) PE=1 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: zinc finger FYVE domain-containing protein 19 isoform X2 [Galeopterus variegatus]
ENSG00000166143(PPP1R14D)	--	0.096512712	1	0	0	0.1955125	1	0.594054	6	2.823569	28	0.574898	6	--	--	--	2.99E-05	4.276384366	up	--	--	--	--	--	--	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of phosphorylation (GO:0042325);; 	"K17557|3.05674e-117|hsa:54866|PPP1R14D, CPI17-like, GBPI-1, GBPI1; protein phosphatase 1, regulatory (inhibitor) subunit 14D; K17557 protein phosphatase 1 regulatory subunit 14D (A)"	--	--	--	PKC-activated protein phosphatase-1 inhibitor;; Putative binding domain	Protein phosphatase 1 regulatory subunit 14D GN=PPP1R14D OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 14D isoform X1 [Bison bison bison]
ENSG00000166145(SPINT1)	--	1.313755325	65	0.945378029	29	1.187325866	60	2.704953403	124	5.188111986	248	1.931240665	90	0.103051344	0.885601637	normal	0	3.010817953	up	0.828964625	0.564969826	normal	0.112945433	1.564159535	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; Molecular Function: protein binding (GO:0005515);; 	"K15619|0|ptr:453342|SPINT1; serine peptidase inhibitor, Kunitz type 1; K15619 Kunitz-type protease inhibitor 1 (A)"	Transcriptional misregulation in cancer (ko05202)	[O]	"Posttranslational modification, protein turnover, chaperones"	Kunitz/Bovine pancreatic trypsin inhibitor domain;; MANEC domain;; Low-density lipoprotein receptor domain class A	Kunitz-type protease inhibitor 1 (Precursor) GN=SPINT1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	hypothetical protein PANDA_001062 [Ailuropoda melanoleuca]
ENSG00000166147(FBN1)	--	5.986690705	1339	4.234841102	977	4.630937593	1065	6.567389689	1527	7.215120326	1686	4.992490802	1161	0.973583629	0.158541405	normal	0.001284788	0.764835733	normal	0.975495409	0.116065207	normal	0.255438096	0.349587948	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K06825|0|hsa:2200|FBN1, ACMICD, ECTOL1, FBN, GPHYSD2, MASS, MFS1, OCTD, SGS, SSKS, WMS, WMS2; fibrillin 1; K06825 fibrillin 1 (A)"	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; EGF-like domain;; TB domain;; Coagulation Factor Xa inhibitory site;; EGF domain	Fibrillin-1 (Precursor) GN=FBN1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: fibrillin-1 [Ovis aries]
ENSG00000166148(AVPR1A)	--	0.1376966	11	0.06982316	6	0.034177732	1	0.05642716	5	0.0996261	7	0.045123375	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04226|0|hsa:552|AVPR1A, AVPR_V1a, AVPR1, V1aR; arginine vasopressin receptor 1A; K04226 arginine vasopressin receptor 1A (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Vascular smooth muscle contraction (ko04270)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Domain of unknown function (DUF1856);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv	Vasopressin V1a receptor GN=AVPR1A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vasopressin V1a receptor [Ochotona princeps]
ENSG00000166153(DEPDC4)	--	1.423586154	40	1.45838676	41	3.06618777	53	0.7930833	31	1.135357	35	1.0773599	36	0.971527344	-0.381854906	normal	0.976466414	-0.240099576	normal	0.930084481	-0.547227511	normal	0.539707827	-0.413880984	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	"Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP)"	DEP domain-containing protein 4 GN=DEPDC4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: DEP domain-containing protein 7-like [Ceratotherium simum simum]
ENSG00000166159(LRTM2)	--	0	0	0	0	0	0	0	0	0	0	0.016195009	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat N-terminal domain;; Leucine rich repeats (6 copies)	Leucine-rich repeat and transmembrane domain-containing protein 2 (Precursor) GN=LRTM2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and transmembrane domain-containing protein 2 [Galeopterus variegatus]
ENSG00000166164(BRD7)	--	30.195662	2287	36.294924	2163	29.4659	2282	29.4328	2463	27.89928	2320	27.70035	2202	0.986970386	0.076078744	normal	0.985955972	0.079610832	normal	0.987019648	-0.059735463	normal	0.9074175	0.031752198	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	"K11723|0|hsa:29117|BRD7, BP75, CELTIX1, NAG4; bromodomain containing 7; K11723 bromodomain-containing protein 7/9 (A)"	--	[K]	Transcription	Domain of unknown function (DUF3512);; Bromodomain	Bromodomain-containing protein 7 GN=BRD7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: bromodomain-containing protein 7 [Odobenus rosmarus divergens]
ENSG00000166165(CKB)	--	33.05510308	790	21.84387552	540	27.71457176	720	34.9769746	1004	58.85634463	1517	31.54725606	848	0.883480242	0.314458891	normal	8.44E-15	1.466206629	up	0.94426646	0.227335478	normal	0.148694039	0.695570257	normal	[E]	Amino acid transport and metabolism	"Molecular Function: kinase activity (GO:0016301);; Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	"K00933|0|ptr:453185|CKB; creatine kinase, brain; K00933 creatine kinase [EC:2.7.3.2] (A)"	Arginine and proline metabolism (ko00330)	[C]	Energy production and conversion	"ATP:guanido phosphotransferase, C-terminal catalytic domain;; ATP:guanido phosphotransferase, N-terminal domain"	Creatine kinase B-type GN=CKB OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: creatine kinase B-type [Ochotona princeps]
ENSG00000166166(TRMT61A)	--	9.267925559	666	8.676592	627	8.149368362	575	10.96615114	723	10.439664	689	10.17761739	697	0.97191344	0.08744756	normal	0.968026966	0.114348819	normal	0.918478244	0.268662545	normal	0.517702162	0.153559852	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: tRNA (adenine-N1-)-methyltransferase activity (GO:0016429);; Biological Process: tRNA methylation (GO:0030488);; Cellular Component: tRNA (m1A) methyltransferase complex (GO:0031515);; 	K07442|0|pps:100977052|TRMT61A; tRNA methyltransferase 61 homolog A (S. cerevisiae); K07442 tRNA (adenine57-N1/adenine58-N1)-methyltransferase [EC:2.1.1.219 2.1.1.220] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	tRNA methyltransferase complex GCD14 subunit;; Methyltransferase domain	tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A GN=TRMT61A OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A [Canis lupus familiaris]
ENSG00000166167(BTRC)	--	9.418168816	661	10.42940895	679	13.00016855	766	10.64070304	740	8.18737917	732	7.341347383	608	0.967079156	0.131753203	normal	0.971626534	0.086819258	normal	0.843655385	-0.340807529	normal	0.90182151	-0.039407298	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: protein dimerization activity (GO:0046983);; 	K03362|0|umr:103678776|BTRC; beta-transducin repeat containing E3 ubiquitin protein ligase; K03362 F-box and WD-40 domain protein 1/11 (A)	Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Circadian rhythm (ko04710)	[S]	Function unknown	"WD domain, G-beta repeat;; D domain of beta-TrCP;; F-box-like;; F-box domain;; Nup133 N terminal like;; Nucleoporin Nup120/160"	F-box/WD repeat-containing protein 1A GN=BTRC OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/WD repeat-containing protein 1A isoform X1 [Oryctolagus cuniculus] 
ENSG00000166169(POLL)	--	8.393729308	415	7.775732252	385	8.308012147	395	9.07962821	442	8.296314071	398	10.40520008	523	0.968649082	0.059887919	normal	0.96841284	0.026381508	normal	0.747983992	0.395347318	normal	0.536569667	0.169035831	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Molecular Function: DNA polymerase activity (GO:0034061);; 	"K03512|0|hsa:27343|POLL, BETAN, POLKAPPA; polymerase (DNA directed), lambda (EC:2.7.7.7); K03512 DNA polymerase lambda [EC:2.7.7.7 4.2.99.-] (A)"	Base excision repair (ko03410);; Non-homologous end-joining (ko03450)	[L]	"Replication, recombination and repair"	DNA polymerase beta palm;; Fingers domain of DNA polymerase lambda;; DNA polymerase beta thumb;; Helix-hairpin-helix domain;; Helix-hairpin-helix domain	DNA polymerase lambda GN=POLL OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase lambda isoform X1 [Loxodonta africana]
ENSG00000166170(BAG5)	--	14.4179341	1127	12.147448	953	14.05853806	1075	13.8433577	1100	14.69016216	1170	13.135253	1048	0.979207845	-0.065725554	normal	0.926130043	0.274140656	normal	0.979566176	-0.044925374	normal	0.850199793	0.051483137	normal	--	--	Molecular Function: chaperone binding (GO:0051087);; 	K09559|0|mcf:101925651|hypothetical protein; K09559 BCL2-associated athanogene 5 (A)	--	[T]	Signal transduction mechanisms	BAG domain	BAG family molecular chaperone regulator 5 GN=BAG5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"BAG family molecular chaperone regulator 5, partial [Bos mutus]"
ENSG00000166171(DPCD)	--	15.0774264	199	21.77045	265	19.626954	249	25.863796	346	19.91025156	238	22.88564023	314	0.017292541	0.762653722	normal	0.951099077	-0.175400502	normal	0.88131351	0.324568277	normal	0.303140765	0.311218828	normal	--	--	--	--	--	--	--	DPCD protein family	Protein DPCD GN=DPCD OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein DPCD isoform X1 [Pteropus alecto]
ENSG00000166173(LARP6)	--	34.8565091	586	31.238937	565	27.89987	581	29.35273	606	29.0898079	604	28.68199	558	0.973448156	0.017539645	normal	0.970247798	0.074677785	normal	0.971233187	-0.066388141	normal	0.98571147	0.008289154	normal	--	--	--	"K18733|0|ptr:453549|LARP6; La ribonucleoprotein domain family, member 6; K18733 la-related protein 6 (A)"	--	[R]	General function prediction only	La domain;; SUZ-C motif	La-related protein 6 GN=LARP6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: la-related protein 6 isoform X1 [Sus scrofa]
ENSG00000166181(API5)	--	49.63956009	2906	53.26193627	3120	55.61672043	3176	57.93820761	3474	54.90159699	3182	48.73362553	2856	0.973724304	0.226621093	normal	0.990296617	0.006957909	normal	0.983535592	-0.161425277	normal	0.926716713	0.026104139	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Apoptosis inhibitory protein 5 (API5)	Apoptosis inhibitor 5 GN=API5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: apoptosis inhibitor 5 isoform X1 [Vicugna pacos]
ENSG00000166183(ASPG)	--	0	0	0	0	0	0	0	0	0.094281876	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[EJ]	"Amino acid transport and metabolism;; Translation, ribosomal structure and biogenesis"	Molecular Function: protein binding (GO:0005515);; 	"K13278|0|hsa:374569|ASPG, C14orf76, GPA/WT; asparaginase (EC:3.1.1.5 3.1.1.47 3.5.1.1); K13278 60kDa lysophospholipase [EC:3.1.1.5 3.1.1.47 3.5.1.1] (A)"	--	[E]	Amino acid transport and metabolism	Asparaginase;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Platelet-activating factor acetylhydrolase GN=ASPG OS=Homo sapiens (Human) PE=2 SV=3	E	Amino acid transport and metabolism	PREDICTED: 60 kDa lysophospholipase [Leptonychotes weddellii]
ENSG00000166188(ZNF319)	--	7.62488	643	9.39576	805	9.40283	807	10.3580652	857	10.21195	853	12.31235	1045	0.761461555	0.382849495	normal	0.975289879	0.062017214	normal	0.80747084	0.363969949	normal	0.205867452	0.268464999	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 319 GN=ZNF319 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 319 [Oryctolagus cuniculus]
ENSG00000166189(HPS6)	--	17.9638	884	15.3482	783	16.8708	864	19.1676	948	17.4684	853	16.8818	835	0.976578757	0.069891116	normal	0.972223007	0.101918247	normal	0.976407528	-0.057444273	normal	0.90091304	0.037133301	normal	--	--	--	--	--	--	--	--	Hermansky-Pudlak syndrome 6 protein GN=HPS6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: Hermansky-Pudlak syndrome 6 protein [Equus caballus]
ENSG00000166192(SENP8)	--	1.646717	76	0.858466	43	0.923606	36	1.035425	51	1.292796	58	1.128301	60	0.8472993	-0.591631682	normal	0.95310355	0.398193578	normal	0.827944316	0.705488989	normal	0.902758197	0.103400852	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K08597|3.32193e-158|hsa:123228|SENP8, DEN1, NEDP1, PRSC2; SUMO/sentrin specific peptidase family member 8 (EC:3.4.22.68); K08597 sentrin-specific protease 8 [EC:3.4.22.68] (A)"	--	[R]	General function prediction only	"Ulp1 protease family, C-terminal catalytic domain"	Sentrin-specific protease 8 GN=SENP8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sentrin-specific protease 8 [Orcinus orca] 
ENSG00000166197(NOLC1)	--	53.08735536	4537	52.792454	4449	58.559655	5039	66.7593	5841	61.06968	5204	44.64695149	3952	0.938390843	0.333544693	normal	0.983835006	0.204648934	normal	0.905355959	-0.358724072	normal	0.828051687	0.074577139	normal	--	--	--	--	--	[Y]	Nuclear structure	"SRP40, C-terminal domain"	Nucleolar and coiled-body phosphoprotein 1 GN=NOLC1 OS=Homo sapiens (Human) PE=1 SV=2	Y	Nuclear structure	PREDICTED: nucleolar and coiled-body phosphoprotein 1 isoform X2 [Tupaia chinensis]
ENSG00000166199(ALKBH3)	--	9.2379661	269	11.32705539	278	10.421167	283	8.451424801	253	10.5814709	288	11.004349	333	0.961014302	-0.118602367	normal	0.96620042	0.02940024	normal	0.937894465	0.22531758	normal	0.899311644	0.054222264	normal	[L]	"Replication, recombination and repair"	--	"K10860|0|ptr:741336|ALKBH3; alkB, alkylation repair homolog 3 (E. coli); K10860 alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 [EC:1.14.11.-] (A)"	--	--	--	2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 GN=ALKBH3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 [Loxodonta africana] 
ENSG00000166200(COPS2)	--	30.84422675	1260	36.63936609	1344	37.8056687	1218	36.50554685	1370	37.11105241	1374	31.53449676	1244	0.979801035	0.089814851	normal	0.982558644	0.010410723	normal	0.981797392	0.022153693	normal	0.886719891	0.039756678	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K12176|0|asn:102382649|COPS2; COP9 signalosome subunit 2; K12176 COP9 signalosome complex subunit 2 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"PCI domain;; COP9 signalosome, subunit CSN8"	COP9 signalosome complex subunit 2 GN=COPS2 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: COP9 signalosome complex subunit 2 isoform X3 [Ursus maritimus] 
ENSG00000166206(GABRB3)	--	63.52428201	4855	55.04555157	4080	54.68937114	4265	41.39566312	3224	55.33826287	4110	55.23489	4178	0.04299952	-0.621208708	normal	0.992039095	-0.010853308	normal	0.992245705	-0.038011073	normal	0.291149948	-0.217816942	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05181|0|hsa:2562|GABRB3, ECA5; gamma-aminobutyric acid (GABA) A receptor, beta 3; K05181 gamma-aminobutyric acid receptor subunit beta (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Gamma-aminobutyric acid receptor subunit beta-3 (Precursor) GN=GABRB3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit beta-3 isoform X2 [Orycteropus afer afer]
ENSG00000166211(SPIC)	--	0	0	0.054719	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09440|2.87384e-160|ptr:740458|SPIC; Spi-C transcription factor (Spi-1/PU.1 related); K09440 transcription factor Spi-C (A)	--	[K]	Transcription	Ets-domain	Transcription factor Spi-C GN=SPIC OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor Spi-C [Loxodonta africana]
ENSG00000166224(SGPL1)	--	21.515389	2162	19.69193	2025	21.11999	2034	22.67943	2324	27.13744	2754	28.21576	2894	0.986536926	0.073360994	normal	0.722386252	0.421908953	normal	0.366234548	0.500140492	normal	0.033040129	0.337255561	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: carboxy-lyase activity (GO:0016831);; Biological Process: carboxylic acid metabolic process (GO:0019752);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K01634|0|hsa:8879|SGPL1, S1PL, SPL; sphingosine-1-phosphate lyase 1 (EC:4.1.2.27); K01634 sphinganine-1-phosphate aldolase [EC:4.1.2.27] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[E]	Amino acid transport and metabolism	Pyridoxal-dependent decarboxylase conserved domain;; Aminotransferase class-V;; Aminotransferase class I and II	Sphingosine-1-phosphate lyase 1 GN=SGPL1 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: sphingosine-1-phosphate lyase 1 isoform X1 [Equus przewalskii]
ENSG00000166225(FRS2)	--	7.86758133	467	6.3154503	483	6.746674726	477	10.48335837	691	10.11728722	728	9.19802841	645	0.257031673	0.53298118	normal	0.163594113	0.569028111	normal	0.651382582	0.425853175	normal	0.004101542	0.511112633	normal	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	"K12461|0|hsa:10818|FRS2, FRS2A, FRS2alpha, SNT, SNT-1, SNT1; fibroblast growth factor receptor substrate 2; K12461 fibroblast growth factor receptor substrate 2 (A)"	Neurotrophin signaling pathway (ko04722);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type)	Fibroblast growth factor receptor substrate 2 GN=FRS2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: fibroblast growth factor receptor substrate 2 [Tupaia chinensis]
ENSG00000166226(CCT2)	--	146.75187	5070	137.6685304	4818	158.700657	5481	176.7694724	6186	177.36998	6073	129.9594081	4479	0.976751761	0.256118466	normal	0.955699087	0.312460893	normal	0.95855848	-0.299462345	normal	0.723064099	0.101248167	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	"K09494|0|ptr:452071|CCT2; chaperonin containing TCP1, subunit 2 (beta); K09494 T-complex protein 1 subunit beta (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	T-complex protein 1 subunit beta GN=CCT2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	T-complex protein 1 subunit beta [Sus scrofa] 
ENSG00000166228(PCBD1)	--	116.188	1817	118.99	1893	120.163	1920	109.689	1722	100.986	1568	102.667	1612	0.982086203	-0.108211528	normal	0.928345039	-0.292917857	normal	0.948038074	-0.260321931	normal	0.213450887	-0.221131391	normal	[H]	Coenzyme transport and metabolism	Biological Process: tetrahydrobiopterin biosynthetic process (GO:0006729);; Molecular Function: 4-alpha-hydroxytetrahydrobiopterin dehydratase activity (GO:0008124);; 	K01724|2.20348e-72|ssc:100155605|PCBD1; pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (EC:4.2.1.96); K01724 4a-hydroxytetrahydrobiopterin dehydratase [EC:4.2.1.96] (A)	--	[K]	Transcription	Pterin 4 alpha carbinolamine dehydratase	Pterin-4-alpha-carbinolamine dehydratase GN=PCBD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PCBD1 protein [Bos taurus]
ENSG00000166233(ARIH1)	--	25.37385646	2810	27.33382332	2966	29.8356497	2918	25.75323011	2843	23.847278	2664	23.0938537	2568	0.989751127	-0.013980695	normal	0.980717125	-0.176256191	normal	0.978079467	-0.192519687	normal	0.541338	-0.12805506	normal	--	--	--	K11968|0|umr:103679136|ARIH1; ariadne RBR E3 ubiquitin protein ligase 1; K11968 ariadne-1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"IBR domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase ARIH1 GN=ARIH1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase ARIH1 [Ursus maritimus]
ENSG00000166246(C16orf71)	--	0.408736	16	0.3778733	12	0.501788679	19	0.362136565	14	0.3291096	9	0.256891282	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C16orf71 GN=C16orf71 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C16orf71 homolog [Galeopterus variegatus]
ENSG00000166250(CLMP)	--	11.822814	1118	8.42163	747	10.25435054	990	7.457392	705	7.847565	712	5.025788136	489	0.007958509	-0.694843166	normal	0.971762861	-0.090469931	normal	8.29E-07	-1.02361371	down	0.051796844	-0.604886271	normal	--	--	--	K06789|0|ptr:736600|CLMP; CXADR-like membrane protein; K06789 adipocyte-specific adhesion molecule (A)	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD47 immunoglobulin-like domain	CXADR-like membrane protein (Precursor) GN=CLMP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CXADR-like membrane protein [Galeopterus variegatus]
ENSG00000166257(SCN3B)	--	0.118517212	12	0.132153251	13	0.404349254	15	0.066876876	6	0.093919908	8	0.166159943	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04847|2.13902e-148|ptr:466810|SCN3B; sodium channel, voltage-gated, type III, beta subunit; K04847 voltage-gated sodium channel type III beta (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain	Sodium channel subunit beta-3 (Precursor) GN=SCN3B OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel subunit beta-3 [Camelus ferus] 
ENSG00000166260(COX11)	--	40.17321099	1787	42.032055	1911	41.49190862	1769	44.39545365	1883	40.21760566	1863	41.0371016	1841	0.985512138	0.044623726	normal	0.985059591	-0.058080109	normal	0.985247931	0.049222886	normal	0.977448148	0.00997839	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: copper ion binding (GO:0005507);; 	"K02258|0|pps:100976343|cytochrome c oxidase assembly protein COX11, mitochondrial; K02258 cytochrome c oxidase assembly protein subunit 11 (A)"	Oxidative phosphorylation (ko00190)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cytochrome c oxidase assembly protein CtaG/Cox11	"Cytochrome c oxidase assembly protein COX11, mitochondrial (Precursor) GN=COX11 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: cytochrome c oxidase assembly protein COX11, mitochondrial-like [Equus caballus] "
ENSG00000166261(ZNF202)	--	3.550700427	281	2.9291553	244	3.069311433	254	3.00723777	231	3.58345666	274	3.53142515	294	0.895321864	-0.311626667	normal	0.956420363	0.145019666	normal	0.945856175	0.201579758	normal	0.980122653	0.016103001	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:7753|ZNF202, ZKSCAN10, ZSCAN42; zinc finger protein 202; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 202 GN=ZNF202 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: zinc finger protein 202 isoform X1 [Equus caballus] 
ENSG00000166262(FAM227B)	--	2.138328	29	1.3910949	23	0.348339	9	0.2885103	6	0.463457701	9	0.652970802	9	0.068062556	-2.045488047	normal	0.857343534	-1.240653385	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function	Protein FAM227B GN=FAM227B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM227B [Galeopterus variegatus]
ENSG00000166263(STXBP4)	--	5.28636	649	5.704076	747	5.685995	740	4.10391	650	5.611887	710	5.163669	750	0.974196275	-0.028543503	normal	0.971394998	-0.094519471	normal	0.976156287	0.011051449	normal	0.902047384	-0.038335093	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15302|0|hsa:252983|STXBP4, Synip; syntaxin binding protein 4; K15302 syntaxin-binding protein 4 (A)"	--	--	--	WW domain;; PDZ domain (Also known as DHR or GLGF)	Syntaxin-binding protein 4 GN=STXBP4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: syntaxin-binding protein 4 [Tupaia chinensis]
ENSG00000166265(CYYR1)	--	0	0	0	0	0	0	0	0	0	0	0.0203758	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF2668)	Cysteine and tyrosine-rich protein 1 (Precursor) GN=CYYR1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: cysteine and tyrosine-rich protein 1 [Galeopterus variegatus]
ENSG00000166266(CUL5)	--	7.929629343	788	9.612031412	955	8.932997025	849	8.138290677	770	8.762815604	829	8.908348835	886	0.974930227	-0.064043119	normal	0.947496345	-0.2251721	normal	0.976851187	0.053158008	normal	0.751610688	-0.081663172	normal	--	--	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	K10612|0|ssc:100525708|CUL5; cullin 5; K10612 cullin 5 (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cullin family;; Cullin protein neddylation domain	Cullin-5 GN=CUL5 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cullin-5 [Orcinus orca] 
ENSG00000166268(MYRFL)	--	0.015627516	1	0.015763556	1	0	0	0.015716009	1	0.093812732	1	0.031023846	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[S]	Function unknown	Myelin gene regulatory factor C-terminal domain 2;; NDT80 / PhoG like DNA-binding  family;; Myelin gene regulatory factor -C-terminal domain 1;; Chaperone of endosialidase	Myelin regulatory factor-like protein GN=MYRFL OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: myelin regulatory factor-like protein [Leptonychotes weddellii]
ENSG00000166272(WBP1L)	--	14.48499968	1162	13.67268253	1108	13.50313655	1096	16.94713512	1353	16.89046199	1346	15.65337682	1261	0.965558206	0.188488384	normal	0.93925022	0.25897285	normal	0.963196535	0.193779573	normal	0.248610433	0.213030312	normal	--	--	--	--	--	--	--	WW domain-binding protein 1	WW domain binding protein 1-like GN=WBP1L OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: WW domain binding protein 1-like isoform X1 [Felis catus]
ENSG00000166275(BORCS7)	--	12.03554	324	12.43669	379	11.42006	369	14.774333	465	13.745484	394	13.45124	432	0.484003254	0.488461938	normal	0.968086221	0.034436456	normal	0.94029186	0.218291438	normal	0.326068056	0.246757491	normal	--	--	--	--	--	--	--	--	UPF0693 protein C10orf32 GN=C10orf32 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0693 protein C10orf32 homolog isoform X1 [Tupaia chinensis]
ENSG00000166278(C2)	--	1.168658249	73	1.223487376	40	1.165695734	73	10.83349398	546	13.07490461	678	13.30683597	734	0	2.846465299	up	0	4.011876829	up	0	3.29500039	up	1.70E-33	3.376318603	up	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01332|0|hsa:717|C2, ARMD14, CO2; complement component 2 (EC:3.4.21.43); K01332 complement component 2 [EC:3.4.21.43] (A)"	Complement and coagulation cascades (ko04610);; Pertussis (ko05133);; Staphylococcus aureus infection (ko05150);; Systemic lupus erythematosus (ko05322)	[E]	Amino acid transport and metabolism	von Willebrand factor type A domain;; Trypsin;; Sushi domain (SCR repeat);; von Willebrand factor type A domain;; Hormone receptor domain	Complement C2a fragment (Precursor) GN=C2 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: complement C2 [Galeopterus variegatus]
ENSG00000166289(PLEKHF1)	--	3.765150784	128	3.010230594	118	3.776864517	145	4.424378594	162	3.94639483	144	3.271748996	123	0.924527239	0.305749471	normal	0.940643385	0.262802369	normal	0.946596376	-0.242931838	normal	0.830269031	0.11211435	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	FYVE zinc finger;; PH domain	Pleckstrin homology domain-containing family F member 1 GN=PLEKHF1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family F member 1 [Ceratotherium simum simum]
ENSG00000166292(TMEM100)	--	0.076410262	2	0.109777782	1	0	0	0.037817943	1	0.148467816	3	0.030597574	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Phosphoinositide-interacting protein family	Transmembrane protein 100 GN=TMEM100 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 100 [Oryctolagus cuniculus] 
ENSG00000166295(ANAPC16)	--	27.285033	1558	25.2574	1450	22.31	1294	23.533514	1350	21.431465	1218	25.830954	1502	0.953295755	-0.237316398	normal	0.933671148	-0.272654601	normal	0.963020036	0.206531526	normal	0.653771455	-0.101143539	normal	--	--	Cellular Component: anaphase-promoting complex (GO:0005680);; Biological Process: cell cycle (GO:0007049);; Biological Process: protein ubiquitination (GO:0016567);; 	--	--	--	--	--	Anaphase-promoting complex subunit 16 GN=ANAPC16 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: anaphase-promoting complex subunit 16 isoform X1 [Sorex araneus]
ENSG00000166311(SMPD1)	--	6.954017556	281	5.738629934	239	6.760537646	292	9.191777359	388	8.0448055	351	13.75254164	604	0.6895305	0.432633663	normal	0.42407067	0.530249704	normal	3.70E-06	1.036475605	up	0.119955879	0.706279767	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	"K12350|0|hsa:6609|SMPD1, ASM, ASMASE, NPD; sphingomyelin phosphodiesterase 1, acid lysosomal (EC:3.1.4.12); K12350 sphingomyelin phosphodiesterase [EC:3.1.4.12] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071);; Lysosome (ko04142)	[I]	Lipid transport and metabolism	Calcineurin-like phosphoesterase	Sphingomyelin phosphodiesterase (Precursor) GN=SMPD1 OS=Homo sapiens (Human) PE=1 SV=4	I	Lipid transport and metabolism	PREDICTED: sphingomyelin phosphodiesterase isoform X2 [Camelus ferus] 
ENSG00000166313(APBB1)	--	13.71522173	746	11.98786192	685	12.7155863	726	15.12950352	791	18.3264907	893	15.21656068	812	0.975282802	0.053562666	normal	0.81632233	0.36043091	normal	0.965088323	0.152917404	normal	0.370862981	0.189582983	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04529|0|pps:100993946|APBB1; amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65); K04529 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) (A)"	Alzheimer's disease (ko05010)	--	--	Phosphotyrosine interaction domain (PTB/PID);; WW domain;; Phosphotyrosine-binding domain	Amyloid beta A4 precursor protein-binding family B member 1 GN=APBB1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: amyloid beta A4 precursor protein-binding family B member 1 isoform X3 [Mustela putorius furo] 
ENSG00000166317(SYNPO2L)	--	0	0	0	0	0	0	0.023961838	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PDZ domain (Also known as DHR or GLGF);; Calcineurin-binding protein (Calsarcin)	Synaptopodin 2-like protein GN=SYNPO2L OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: synaptopodin 2-like isoform 1 [Sus scrofa]
ENSG00000166321(NUDT13)	--	2.85979992	100	2.658172	97	2.784840794	98	1.499519297	54	1.684843011	54	2.228499008	74	0.173300463	-0.900663055	normal	0.281705981	-0.848466778	normal	0.916286641	-0.406308664	normal	0.080642587	-0.717038788	normal	[L]	"Replication, recombination and repair"	Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[L]	"Replication, recombination and repair"	NUDIX domain;; NADH pyrophosphatase-like rudimentary NUDIX domain;; NADH pyrophosphatase zinc ribbon domain	Nucleoside diphosphate-linked moiety X motif 13 OS=Homo sapiens (Human) PE=2 SV=3	L	"Replication, recombination and repair"	PREDICTED: nucleoside diphosphate-linked moiety X motif 13 isoform X1 [Equus przewalskii] 
ENSG00000166323(C11orf65)	--	0.382605216	6	0.382335442	6	0.089883265	2	0.489813905	6	0.397069012	5	0.3213205	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf65 GN=C11orf65 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C11orf65 homolog [Ceratotherium simum simum]
ENSG00000166326(TRIM44)	--	20.50661044	2884	20.62731314	3143	20.24680931	2981	23.96391047	3583	27.747666	3849	26.27950948	3749	0.954519829	0.282129557	normal	0.962395835	0.270796929	normal	0.929218027	0.322271919	normal	0.079245791	0.290708971	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	K12020|6.5593e-173|ocu:100350550|TRIM44; tripartite motif containing 44; K12020 tripartite motif-containing protein 44 (A)	--	--	--	B-box zinc finger	Tripartite motif-containing protein 44 GN=TRIM44 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: tripartite motif-containing protein 44 [Oryctolagus cuniculus]
ENSG00000166333(ILK)	--	49.718755	1757	46.624828	1666	54.3296522	1947	51.384575	1666	47.95689502	1682	44.844249	1584	0.981746608	-0.107461531	normal	0.984781021	-0.00763036	normal	0.916863099	-0.305708241	normal	0.479153582	-0.143822872	normal	[R]	General function prediction only	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06272|0|cjc:100406751|ILK; integrin-linked kinase; K06272 integrin-linked kinase [EC:2.7.11.1] (A)	PPAR signaling pathway (ko03320);; Focal adhesion (ko04510);; Bacterial invasion of epithelial cells (ko05100);; Endometrial cancer (ko05213)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Protein kinase domain;; Ankyrin repeats (many copies);; Ankyrin repeat	Integrin-linked protein kinase GN=ILK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: integrin-linked protein kinase isoform 1 [Canis lupus familiaris] 
ENSG00000166337(TAF10)	--	73.43638872	1250	78.95686	1310	68.70657105	1251	72.70884463	1289	72.65436631	1243	61.86089807	1074	0.982191511	0.013475595	normal	0.978541898	-0.097052036	normal	0.951977579	-0.228081356	normal	0.658860259	-0.101526714	normal	[K]	Transcription	"Cellular Component: nucleus (GO:0005634);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	"K03134|1.64244e-77|pps:100987353|TAF10; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa; K03134 transcription initiation factor TFIID subunit 10 (A)"	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	Transcription initiation factor TFIID 23-30kDa subunit	Transcription initiation factor TFIID subunit 10 GN=TAF10 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: transcription initiation factor TFIID subunit 10, partial [Panthera tigris altaica]"
ENSG00000166340(TPP1)	--	52.12219815	2966	59.52299045	3384	48.81442392	2795	40.96172401	2340	43.97011998	2539	67.462744	3871	0.847464426	-0.372624417	normal	0.697274889	-0.435670108	normal	0.585410358	0.461353566	normal	0.878142483	-0.083630135	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type peptidase activity (GO:0008236);; 	"K01279|0|hsa:1200|TPP1, CLN2, LPIC, SCAR7, TPP-1; tripeptidyl peptidase I (EC:3.4.14.9); K01279 tripeptidyl-peptidase I [EC:3.4.14.9] (A)"	Lysosome (ko04142)	--	--	"Pro-kumamolisin, activation domain;; Subtilase family"	Tripeptidyl-peptidase 1 (Precursor) GN=TPP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: tripeptidyl-peptidase 1 [Loxodonta africana]
ENSG00000166341(DCHS1)	--	0.0573854	13	0.0649279	15	0.122933	28	0.0311424	7	0.0301169	6	0.0394461	9	--	--	--	--	--	--	0.5292784	-1.496721728	normal	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16507|0|hsa:8642|DCHS1, CDH19, CDH25, CDHR6, FIB1, PCDH16, VMLDS1; dachsous cadherin-related 1; K16507 protocadherin-16/23 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like;; Cadherin prodomain like	Protocadherin-16 (Precursor) GN=DCHS1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protocadherin-16 [Equus caballus] 
ENSG00000166342(NETO1)	--	0.0367245	2	0	0	0	0	0.0182314	1	0.071035222	3	0.042784215	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CUB domain;; Low-density lipoprotein receptor domain class A	Neuropilin and tolloid-like protein 1 (Precursor) GN=NETO1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: neuropilin and tolloid-like protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000166343(MSS51)	--	0.342729356	16	0.3388314	15	0.370991057	16	0.580975031	25	0.5490445	25	0.427597809	18	0.976546515	0.569029139	normal	0.968094103	0.663286968	normal	--	--	--	--	--	--	--	--	--	"K17656|0|hsa:118490|MSS51, ZMYND17; MSS51 mitochondrial translational activator; K17656 mitochondrial splicing suppressor protein 51 (A)"	--	--	--	MYND finger	"Putative protein MSS51 homolog, mitochondrial GN=MSS51 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: putative protein MSS51 homolog, mitochondrial isoform X1 [Equus caballus] "
ENSG00000166347(CYB5A)	--	72.7111396	971	54.05920304	791	64.15469002	940	56.87922	768	61.6583	838	71.18478	977	0.795295676	-0.368539777	normal	0.975084682	0.061731321	normal	0.978275782	0.047331668	normal	0.747209522	-0.085283835	normal	[CI]	Energy production and conversion;; Lipid transport and metabolism	--	--	--	[C]	Energy production and conversion	Cytochrome b5-like Heme/Steroid binding domain	Cytochrome b5 GN=CYB5A OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: cytochrome b5 [Galeopterus variegatus]
ENSG00000166348(USP54)	--	4.698013219	616	5.131835128	634	4.425417755	576	4.82287159	596	4.531264575	547	5.704947452	695	0.971021959	-0.07825184	normal	0.936708473	-0.233767607	normal	0.922796776	0.262025577	normal	0.978728302	-0.011471174	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase	Inactive ubiquitin carboxyl-terminal hydrolase 54 GN=USP54 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: inactive ubiquitin carboxyl-terminal hydrolase 54 isoform X1 [Galeopterus variegatus]
ENSG00000166349(RAG1)	--	0.114868	13	0.0704536	8	0.140732	15	0.105856	12	0.180477	20	0.105698	12	--	--	--	0.92514407	1.158327057	normal	--	--	--	--	--	--	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: endonuclease activity (GO:0004519);; Biological Process: V(D)J recombination (GO:0033151);; Molecular Function: sequence-specific DNA binding (GO:0043565);; Molecular Function: metal ion binding (GO:0046872);; Molecular Function: ubiquitin protein ligase activity (GO:0061630);; 	"K10628|0|hsa:5896|RAG1, RAG-1, RNF74; recombination activating gene 1; K10628 V(D)J recombination-activating protein 1 [EC:6.3.2.19] (A)"	FoxO signaling pathway (ko04068);; Primary immunodeficiency (ko05340)	--	--	"Recombination-activation protein 1 (RAG1);; Recombination-activating protein 1 zinc-finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RAG1 GN=RAG1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: V(D)J recombination-activating protein 1 [Myotis brandtii]
ENSG00000166352(C11orf74)	--	17.24778212	193	17.49135049	169	18.73171555	198	17.60940688	184	19.92989397	200	24.36928297	237	0.963435078	-0.098920692	normal	0.943804726	0.219740958	normal	0.933297391	0.249352257	normal	0.760391971	0.128928741	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf74 GN=C11orf74 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C11orf74 homolog isoform X1 [Galeopterus variegatus]
ENSG00000166359(WDR88)	--	0.3619484	14	0.835729	34	0.217980144	8	0.297184181	12	0.218286284	8	0.222254	9	--	--	--	0.041950347	-1.919721852	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Nucleoporin Nup120/160;; PQQ enzyme repeat"	WD repeat-containing protein 88 GN=WDR88 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 88 [Galeopterus variegatus]
ENSG00000166377(ATP9B)	--	4.930806567	331	5.483154922	383	4.746102351	338	8.234357815	607	7.832402337	549	10.286209	801	0.000677261	0.841109022	normal	0.438606965	0.496390067	normal	1.64E-09	1.232794527	up	0.00149329	0.87498662	normal	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:374868|ATP9B, ATPASEP, ATPIIB, NEO1L, hMMR1; ATPase, class II, type 9B (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[P]	Inorganic ion transport and metabolism	E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase IIB GN=ATP9B OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase IIB isoform X1 [Loxodonta africana]
ENSG00000166387(PPFIBP2)	--	7.630448166	530	10.16503319	740	8.31694085	624	5.667327482	394	5.310538026	352	11.61175409	726	0.565470538	-0.457085771	normal	4.15E-07	-1.090069112	down	0.948577326	0.209660588	normal	0.505119527	-0.383088933	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; DNA binding domain of tn916 integrase	Liprin-beta-2 GN=PPFIBP2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: liprin-beta-2 isoform X5 [Equus caballus]
ENSG00000166394(CYB5R2)	--	0.964510926	22	0.996777757	22	1.092031244	28	1.514538284	35	2.029042116	46	1.045082746	26	0.957313297	0.605261633	normal	0.660110409	0.994489295	normal	0.985402901	-0.109090774	normal	0.427630066	0.550250051	normal	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00326|0|hsa:51700|CYB5R2, B5R.2; cytochrome b5 reductase 2 (EC:1.6.2.2); K00326 cytochrome-b5 reductase [EC:1.6.2.2] (A)"	Amino sugar and nucleotide sugar metabolism (ko00520)	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Oxidoreductase FAD-binding domain;; Oxidoreductase NAD-binding domain;; Ferric reductase NAD binding domain	NADH-cytochrome b5 reductase 2 GN=CYB5R2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADH-cytochrome b5 reductase 2 isoform X2 [Galeopterus variegatus]
ENSG00000166396(SERPINB7)	--	2.14364557	49	1.441163277	43	2.72429796	72	2.404437	73	2.366921341	78	3.26327232	47	0.898259269	0.530575745	normal	0.528710102	0.81611535	normal	0.849264059	-0.60771212	normal	0.696661854	0.250426153	normal	--	--	--	"K13964|0|ptr:468623|SERPINB7; serpin peptidase inhibitor, clade B (ovalbumin), member 7; K13964 serpin B7 (A)"	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B7 GN=SERPINB7 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: serpin B7 isoform X2 [Canis lupus familiaris] 
ENSG00000166398(KIAA0355)	--	7.458878	969	9.405724747	1104	8.733306	1112	8.042903	1037	7.125744291	921	9.499988	1185	0.977863062	0.066912495	normal	0.918915292	-0.282469368	normal	0.978631909	0.083329035	normal	0.889086616	-0.039893745	normal	--	--	--	--	--	--	--	--	Uncharacterized protein KIAA0355 GN=KIAA0355 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA0355 homolog [Galeopterus variegatus]
ENSG00000166401(SERPINB8)	--	3.182487104	169	3.6820751	196	2.790023895	160	4.58249399	246	6.409461	325	7.482624074	388	0.602121722	0.506963085	normal	0.059121814	0.703899959	normal	9.12E-08	1.26178838	up	0.006933934	0.849135482	normal	--	--	--	"K13963|0|ptr:455461|SERPINB8; serpin peptidase inhibitor, clade B (ovalbumin), member 8; K13963 serpin B (A)"	Amoebiasis (ko05146)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B8 GN=SERPINB8 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: heparin cofactor 2-like [Ceratotherium simum simum]
ENSG00000166402(TUB)	--	10.63186861	1306	11.14852536	1391	12.47050025	1543	7.914607201	974	7.344419001	895	6.460040815	794	0.528488536	-0.453373339	normal	0.020955825	-0.656691646	normal	2.02E-06	-0.96547473	normal	1.56E-06	-0.692576286	normal	--	--	--	--	--	[R]	General function prediction only	Tub family	Tubby protein homolog GN=TUB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: tubby protein homolog [Equus caballus]
ENSG00000166405(RIC3)	--	1.855430594	64	2.128675	69	2.3618235	81	0.7346105	29	1.343223299	48	1.982476	67	0.160197774	-1.131459784	normal	0.898804182	-0.53095765	normal	0.958305271	-0.27637017	normal	0.233425462	-0.589960514	normal	--	--	--	--	--	--	--	Resistance to inhibitors of cholinesterase homologue 3	Protein RIC-3 (Precursor) GN=RIC3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein RIC-3 isoform 1 [Trichechus manatus latirostris]
ENSG00000166407(LMO1)	--	1.349019402	13	0.714203329	8	0.61513997	11	1.748153036	22	5.70078345	64	3.547446641	36	0.975998155	0.667024656	normal	1.32E-07	2.764425879	up	0.181900032	1.576394425	normal	0.051101264	1.911214544	normal	--	--	--	--	--	[R]	General function prediction only	LIM domain	Rhombotin-1 GN=LMO1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	hypothetical protein PANDA_004271 [Ailuropoda melanoleuca]
ENSG00000166411(IDH3A)	--	31.2812063	797	30.47841	770	35.1719935	891	33.5600708	789	27.0963186	737	30.3373545	722	0.976009239	-0.045298919	normal	0.972660289	-0.08445083	normal	0.885268189	-0.311130265	normal	0.509389078	-0.150071227	normal	[CE]	Energy production and conversion;; Amino acid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00030|0|hsa:3419|IDH3A; isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41); K00030 isocitrate dehydrogenase (NAD+) [EC:1.1.1.41] (A)	Citrate cycle (TCA cycle) (ko00020);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Isocitrate/isopropylmalate dehydrogenase	"Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial (Precursor) GN=IDH3A OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial [Loxodonta africana]"
ENSG00000166415(WDR72)	--	10.2564853	972	10.37681261	1006	10.451364	990	10.30487788	987	10.97086396	1076	12.477617	1217	0.979280556	-0.008724807	normal	0.97739724	0.075511446	normal	0.914965249	0.289138269	normal	0.581237946	0.123645555	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Nucleoporin Nup120/160"	WD repeat-containing protein 72 GN=WDR72 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 72 [Equus caballus]
ENSG00000166426(CRABP1)	--	0.351291	4	0.0858002	1	0.0835355	0	0.0853195	1	0.0845917	0	0.0860207	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K17337|3.1755e-98|ssc:100169745|CRABP1; cellular retinoic acid binding protein 1; K17337 cellular retinoic acid-binding protein 1 (A)	--	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin / cytosolic fatty-acid binding protein family	Cellular retinoic acid-binding protein 1 GN=CRABP1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: cellular retinoic acid-binding protein 1 [Odobenus rosmarus divergens] 
ENSG00000166428(PLD4)	--	0.030525746	4	0.251182886	4	0.007277178	0	0.030501424	4	0.014889765	1	0.00754136	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: catalytic activity (GO:0003824);; 	"K16860|0|hsa:122618|PLD4, C14orf175; phospholipase D family, member 4 (EC:3.1.4.4); K16860 phospholipase D3/4 [EC:3.1.4.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565)	[R]	General function prediction only	PLD-like domain;; PLD-like domain;; Phospholipase D Active site motif	Phospholipase D4 GN=PLD4 OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: phospholipase D4 [Galeopterus variegatus]
ENSG00000166432(ZMAT1)	--	0.155516335	11	0.028856204	2	0.114845245	7	0.04238655	3	0.068285465	4	0.12636559	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; U1 zinc finger	Zinc finger matrin-type protein 1 GN=ZMAT1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger matrin-type protein 1 isoform X1 [Equus caballus]
ENSG00000166435(XRRA1)	--	4.104455359	367	3.4698095	380	3.749353503	409	3.735039246	375	3.2878838	358	3.875591232	431	0.969107911	0.000277121	normal	0.962808205	-0.10702747	normal	0.968167815	0.06705404	normal	0.984748025	-0.010693877	normal	--	--	--	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	X-ray radiation resistance-associated protein 1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: X-ray radiation resistance-associated protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000166436(TRIM66)	--	2.450371038	457	2.228870241	416	1.974398794	370	1.69362	312	2.082631482	389	1.829475	344	0.188782303	-0.579108271	normal	0.96222305	-0.117796979	normal	0.96288176	-0.11292933	normal	0.270806532	-0.271406551	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	K12032|0|pps:100976248|TRIM66; tripartite motif containing 66; K12032 tripartite motif-containing protein 66 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Bromodomain;; B-box zinc finger;; PHD-finger	Tripartite motif-containing protein 66 GN=TRIM66 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 66 isoform X1 [Galeopterus variegatus]
ENSG00000166439(RNF169)	--	3.833367	503	3.964954049	537	4.114416003	517	4.427737	598	4.343929	553	5.053472	661	0.94248122	0.218143143	normal	0.971781057	0.02087291	normal	0.836519466	0.345299146	normal	0.395600158	0.197860994	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF169 GN=RNF169 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF169 [Orcinus orca]
ENSG00000166441(RPL27A)	--	741.5707052	9124	683.5056948	8588	726.2811298	8889	925.3272092	10743	836.8346755	10279	818.6668904	9800	0.990897068	0.204794502	normal	0.987032312	0.237840939	normal	0.994241261	0.132447712	normal	0.355341612	0.191034661	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02900|1.13857e-87|pps:100976591|RPL27A; ribosomal protein L27a; K02900 large subunit ribosomal protein L27Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L18e/L15	60S ribosomal protein L27a GN=RPL27A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L27a-like [Ovis aries] 
ENSG00000166444(ST5)	--	3.5371389	169	5.09206973	225	12.17522345	202	7.110228059	355	11.26283604	477	7.10625502	406	5.72E-05	1.033342378	up	8.73E-06	1.057645475	up	7.10E-05	0.993482403	normal	1.31E-06	1.033922309	up	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; uDENN domain;; dDENN domain	Suppression of tumorigenicity 5 protein GN=ST5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: suppression of tumorigenicity 5 protein isoform X1 [Galeopterus variegatus] 
ENSG00000166446(CDYL2)	--	0.3441111	47	0.279039676	40	0.369536313	48	0.407481507	54	0.361573668	44	0.1437093	20	0.976158004	0.164448498	normal	0.978847614	0.112037363	normal	0.303315274	-1.210499024	normal	0.787028745	-0.217700396	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	--	--	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family;; Chromo (CHRromatin Organisation MOdifier) domain	Chromodomain Y-like protein 2 GN=CDYL2 OS=Homo sapiens (Human) PE=1 SV=2	BI	Chromatin structure and dynamics;; Lipid transport and metabolism	PREDICTED: chromodomain Y-like protein 2 [Trichechus manatus latirostris]
ENSG00000166448(TMEM130)	--	0.749508622	47	0.401100308	23	0.418511894	24	0.226615785	13	0.472053793	28	0.506935896	28	0.010039701	-1.768107236	normal	0.98304497	0.247594001	normal	0.984591803	0.202290225	normal	0.609494883	-0.465562972	normal	--	--	--	--	--	--	--	PKD domain	Transmembrane protein 130 (Precursor) GN=TMEM130 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	Transmembrane protein 130 [Tupaia chinensis]
ENSG00000166450(PRTG)	--	9.589292207	850	8.398526106	761	10.60752296	758	5.990439079	488	8.279146894	525	5.023614775	435	0.000376881	-0.829408029	normal	0.191497341	-0.555667923	normal	0.000884135	-0.807319863	normal	7.35E-06	-0.73175522	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	"Fibronectin type III domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Interferon-alpha/beta receptor, fibronectin type III"	Protogenin (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protogenin [Panthera tigris altaica]
ENSG00000166451(CENPN)	--	25.53350416	1184	29.08081577	1283	27.88589728	1323	29.17760373	1216	28.98955231	1264	29.90752192	1306	0.981607115	0.007632112	normal	0.981261379	-0.042900318	normal	0.982444041	-0.026918637	normal	0.942531704	-0.022378593	normal	--	--	Biological Process: chromosome segregation (GO:0007059);; Biological Process: centromere complex assembly (GO:0034508);; 	K11506|0|mcf:102145649|CENPN; centromere protein N; K11506 centromere protein N (A)	--	--	--	Kinetochore protein CHL4 like	Centromere protein N GN=CENPN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centromere protein N [Camelus bactrianus]
ENSG00000166452(AKIP1)	--	23.8302402	408	23.976027	418	26.26040645	398	25.269349	398	23.35747427	414	30.61615	469	0.967755134	-0.066379877	normal	0.968703668	-0.035170874	normal	0.936952845	0.227730099	normal	0.903323627	0.044896663	normal	--	--	--	--	--	--	--	--	A-kinase-interacting protein 1 GN=AKIP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: A-kinase-interacting protein 1 [Galeopterus variegatus]
ENSG00000166454(ATMIN)	--	16.66384	1475	16.252137	1420	15.67376572	1367	18.29701323	1594	19.017143	1682	17.46450212	1547	0.982176088	0.081023216	normal	0.960281753	0.222642144	normal	0.972016201	0.16999163	normal	0.427917775	0.15706756	normal	--	--	--	--	--	[R]	General function prediction only	C2H2-type zinc finger	ATM interactor GN=ATMIN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ATM interactor [Loxodonta africana]
ENSG00000166471(TMEM41B)	--	26.36370768	1153	27.9259538	1257	26.82919014	1134	19.993092	911	22.56193543	987	31.31612529	1280	0.796512937	-0.370145412	normal	0.808227648	-0.369785792	normal	0.96964507	0.166222965	normal	0.494073163	-0.177557072	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	SNARE associated Golgi protein	Transmembrane protein 41B GN=TMEM41B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 41B [Tupaia chinensis]
ENSG00000166477(LEO1)	--	17.53512878	975	18.809574	1046	19.05080649	1053	19.29411122	1081	18.48024636	1015	16.46311185	909	0.974121896	0.117883669	normal	0.97787274	-0.064734666	normal	0.951447301	-0.220104125	normal	0.843370735	-0.054391888	normal	--	--	Biological Process: transcription elongation from RNA polymerase II promoter (GO:0006368);; Biological Process: histone modification (GO:0016570);; Cellular Component: Cdc73/Paf1 complex (GO:0016593);; 	"K15177|0|ptr:453438|LEO1; Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae); K15177 RNA polymerase-associated protein LEO1 (A)"	--	[S]	Function unknown	Leo1-like protein	RNA polymerase-associated protein LEO1 GN=LEO1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: RNA polymerase-associated protein LEO1-like isoform 1 [Ceratotherium simum simum]
ENSG00000166478(ZNF143)	--	5.629554501	277	5.356637376	293	5.995331856	316	7.67220985	394	8.584149121	361	5.135972752	273	0.564092684	0.475257126	normal	0.911255082	0.278375212	normal	0.940552921	-0.218190554	normal	0.516872354	0.192414202	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 143 GN=ZNF143 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 143 isoform X1 [Equus caballus] 
ENSG00000166479(TMX3)	--	20.046834	1362	20.589425	1383	21.823459	1402	20.524241	1372	18.660886	1264	18.416529	1215	0.982929706	-0.020255719	normal	0.97324501	-0.151058396	normal	0.95928027	-0.214572623	normal	0.54865854	-0.128369687	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	"K09585|0|hsa:54495|TMX3, PDIA13, TXNDC10; thioredoxin-related transmembrane protein 3 (EC:5.3.4.1); K09585 thioredoxin domain-containing protein 10 [EC:5.3.4.1] (A)"	--	[R]	General function prediction only	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like domain;; Calsequestrin	Protein disulfide-isomerase TMX3 (Precursor) GN=TMX3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein disulfide-isomerase TMX3 [Leptonychotes weddellii]
ENSG00000166482(MFAP4)	--	0.49113655	15	1.37692444	42	0.63895063	19	0.5578949	17	0.50896504	15	0.574231886	18	--	--	--	0.176962333	-1.417956064	normal	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Microfibril-associated glycoprotein 4 (Precursor) GN=MFAP4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	hypothetical protein PANDA_012254 [Ailuropoda melanoleuca]
ENSG00000166483(WEE1)	--	14.85666633	769	17.65721185	861	17.16867071	861	15.51218384	765	16.67634925	823	14.57271313	728	0.975855662	-0.038279433	normal	0.973943376	-0.08639214	normal	0.933695633	-0.24988831	normal	0.591922729	-0.126295575	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06632|0|ptr:466440|WEE1; WEE1 G2 checkpoint kinase; K06632 wee1-like protein kinase [EC:2.7.11.1] (A)	Cell cycle (ko04110)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase	Wee1-like protein kinase GN=WEE1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: wee1-like protein kinase isoform X1 [Sus scrofa]
ENSG00000166484(MAPK7)	--	8.66724	490	9.276575	528	10.39383449	508	9.369652074	505	8.532963753	479	9.468458985	518	0.971611664	0.012630365	normal	0.957261764	-0.161453083	normal	0.9719293	0.019773864	normal	0.898714033	-0.044026886	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04464|0|hsa:5598|MAPK7, BMK1, ERK4, ERK5, PRKM7; mitogen-activated protein kinase 7 (EC:2.7.11.24); K04464 mitogen-activated protein kinase 7 [EC:2.7.11.24] (A)"	MAPK signaling pathway (ko04010);; Gap junction (ko04540);; Neurotrophin signaling pathway (ko04722);; GnRH signaling pathway (ko04912);; Oxytocin signaling pathway (ko04921);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase 7 GN=MAPK7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 7 [Mustela putorius furo] 
ENSG00000166501(PRKCB)	--	0.017688748	1	0.123104759	8	0.018249	2	0	0	0	0	0.171419424	3	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K02677|0|hsa:5579|PRKCB, PKC-beta, PKCB, PRKCB1, PRKCB2; protein kinase C, beta (EC:2.7.11.13); K02677 classical protein kinase C [EC:2.7.11.13] (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Tight junction (ko04530);; Gap junction (ko04540);; Natural killer cell mediated cytotoxicity (ko04650);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Aldosterone-regulated sodium reabsorption (ko04960);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Carbohydrate digestion and absorption (ko04973);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Vibrio cholerae infection (ko05110);; Leishmaniasis (ko05140);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2 domain;; Protein kinase C terminal domain	Protein kinase C beta type GN=PRKCB OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: protein kinase C beta type isoform X1 [Ochotona princeps]
ENSG00000166503(RP11-382A20.3)	--	8.986515418	1693	9.201671	1647	9.7033775	1780	9.3285279	1727	10.0202111	1730	7.4628271	1416	0.985376952	-0.002144227	normal	0.984173387	0.049460612	normal	0.87513074	-0.338024693	normal	0.685770738	-0.092933704	normal	--	--	--	--	--	[K]	Transcription	PWWP domain	Hepatoma-derived growth factor-related protein 3 GN=HDGFRP3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hepatoma-derived growth factor-related protein 3-like [Ochotona princeps]
ENSG00000166507(NDST2)	--	6.920817279	408	5.205355933	361	5.816402	371	5.875811	354	4.689003273	297	7.102313	392	0.933439826	-0.234702181	normal	0.895041565	-0.30156717	normal	0.967143962	0.070861991	normal	0.620321721	-0.149291699	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Molecular Function: [heparan sulfate]-glucosamine N-sulfotransferase activity (GO:0015016);; Molecular Function: hydrolase activity (GO:0016787);; 	"K02577|0|hsa:8509|NDST2, HSST2, NST2; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (EC:2.8.2.8); K02577 heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.1.1.- 2.8.2.-] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	heparan sulfate-N-deacetylase;; Sulfotransferase domain	Heparan sulfate N-sulfotransferase 2 GN=NDST2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2 [Odobenus rosmarus divergens]
ENSG00000166508(MCM7)	--	91.40324	5545	97.30656	6019	98.69701935	6101	88.5759458	5391	89.999476	5430	77.433162	4707	0.993207468	-0.071446735	normal	0.989063278	-0.169953194	normal	0.882996875	-0.382421083	normal	0.272993668	-0.207493431	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; Molecular Function: ATPase activity (GO:0016887);; 	K02210|0|pps:100985652|MCM7; minichromosome maintenance complex component 7; K02210 DNA replication licensing factor MCM7 [EC:3.6.4.12] (A)	DNA replication (ko03030);; Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	"MCM2/3/5 family;; MCM N-terminal domain;; Magnesium chelatase, subunit ChlI;; AAA domain (dynein-related subfamily)"	DNA replication licensing factor MCM7 GN=MCM7 OS=Homo sapiens (Human) PE=1 SV=4	L	"Replication, recombination and repair"	PREDICTED: DNA replication licensing factor MCM7 [Ceratotherium simum simum]
ENSG00000166510(CCDC68)	--	2.295692678	163	1.62887655	98	2.067642411	144	1.983795647	144	3.290416596	234	2.329558473	167	0.95118626	-0.207552226	normal	1.65E-05	1.221660777	up	0.951680944	0.203501657	normal	0.398056835	0.40803158	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 68 GN=CCDC68 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 68 [Ceratotherium simum simum]
ENSG00000166523(CLEC4E)	--	0	0	0	0	0	0	0.432080212	9	0.235155566	7	1.065409936	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10059|1.92464e-161|hsa:26253|CLEC4E, CLECSF9, MINCLE; C-type lectin domain family 4, member E; K10059 C-type lectin domain family 4 member E (A)"	Tuberculosis (ko05152)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 4 member E GN=CLEC4E OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 4 member E [Pteropus alecto]
ENSG00000166526(ZNF3)	--	15.238388	594	12.647609	526	12.49576841	523	13.09606885	581	14.79582	639	16.2685009	651	0.971692203	-0.062593318	normal	0.923730119	0.258650996	normal	0.88563796	0.306758618	normal	0.493502905	0.166558928	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7551|ZNF3, A8-51, HF.12, KOX25, PP838, Zfp113; zinc finger protein 3; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 3 GN=ZNF3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 3-like isoform X1 [Leptonychotes weddellii]
ENSG00000166529(ZSCAN21)	--	4.168055295	87	4.738756647	91	4.341036	88	3.2742734	62	4.818713919	107	5.4703962	121	0.877863163	-0.508878826	normal	0.958051445	0.209039383	normal	0.871252544	0.44459858	normal	0.875330728	0.105355853	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09230|0|pps:103785590|ZSCAN21; zinc finger and SCAN domain containing 21; K09230 SCAN domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and SCAN domain-containing protein 21 GN=ZSCAN21 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 21 [Galeopterus variegatus]
ENSG00000166532(RIMKLB)	--	15.93241876	1250	14.64632625	1179	10.74305749	930	13.8399903	1069	14.28575303	1087	15.02911761	1192	0.938617386	-0.256157598	normal	0.972662377	-0.138453315	normal	0.839393119	0.349287256	normal	0.940617376	-0.026040858	normal	[HJ]	"Coenzyme transport and metabolism;; Translation, ribosomal structure and biogenesis"	Molecular Function: glutathione synthase activity (GO:0004363);; Molecular Function: ATP binding (GO:0005524);; Biological Process: glutathione biosynthetic process (GO:0006750);; Molecular Function: metal ion binding (GO:0046872);; 	"K18310|0|ptr:735860|RIMKLB, NAAGS; ribosomal modification protein rimK-like family member B; K18310 beta-citrylglutamate/N-acetylaspartylglutamate synthase [EC:6.3.1.17 6.3.2.41] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250)"	--	--	"RimK-like ATP-grasp domain;; Prokaryotic glutathione synthetase, ATP-grasp domain;; ATP-grasp domain;; ATP-grasp domain"	Beta-citrylglutamate synthase B GN=RIMKLB OS=Homo sapiens (Human) PE=2 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: beta-citryl-glutamate synthase B isoformX1 [Sus scrofa] 
ENSG00000166546(BEAN1)	--	6.309724468	284	5.164589216	227	4.762953313	237	4.22170051	233	5.676596348	286	3.251789765	162	0.892754546	-0.314511061	normal	0.895813954	0.310052559	normal	0.479763226	-0.552891348	normal	0.734969582	-0.157414699	normal	--	--	--	--	--	--	--	--	Protein BEAN1 GN=BEAN1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein BEAN1 [Camelus dromedarius]
ENSG00000166548(TK2)	--	13.50202002	769	12.12055762	718	12.7924191	705	13.46169654	756	16.74489878	895	13.99902844	785	0.975117004	-0.055318154	normal	0.902035585	0.295918061	normal	0.965762521	0.146480056	normal	0.579285972	0.131187545	normal	--	--	--	"K00857|0|pps:100987041|TK2; thymidine kinase 2, mitochondrial; K00857 thymidine kinase [EC:2.7.1.21] (A)"	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Deoxynucleoside kinase;; AAA domain;; AAA domain	"Thymidine kinase 2, mitochondrial (Precursor) GN=TK2 OS=Homo sapiens (Human) PE=1 SV=4"	F	Nucleotide transport and metabolism	"PREDICTED: thymidine kinase 2, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000166557(TMED3)	--	113.117873	2966	107.218597	2848	103.68285	2789	108.130617	2786	108.245906	2851	107.350187	2712	0.986463029	-0.121090865	normal	0.989472998	-0.019897105	normal	0.989066318	-0.048655442	normal	0.793791908	-0.064549006	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 3 (Precursor) GN=TMED3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 3 [Camelus ferus] 
ENSG00000166562(SEC11C)	--	24.82731	396	31.43084	503	26.711105	427	25.36476	422	18.503758	306	24.44887	431	0.968206823	0.060682223	normal	0.012513525	-0.735587104	normal	0.970382706	0.00514223	normal	0.462966553	-0.215610738	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K13280|6.52686e-137|pon:100174381|SEC11C, SEC11L3; SEC11 homolog C (S. cerevisiae) (EC:3.4.21.89); K13280 signal peptidase, endoplasmic reticulum-type [EC:3.4.-.-] (A)"	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Peptidase S24-like	Signal peptidase complex catalytic subunit SEC11C GN=SEC11C OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal peptidase complex catalytic subunit SEC11C [Orcinus orca] 
ENSG00000166569(CPLX4)	--	0	0	0	0	0	0	0	0	0	0	0.0264088	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: neurotransmitter transport (GO:0006836);; Molecular Function: syntaxin binding (GO:0019905);; 	K15295|3.39014e-90|nle:100592432|CPLX4; complexin 4; K15295 complexin-3/4 (A)	Synaptic vesicle cycle (ko04721)	--	--	Synaphin protein	Complexin-4 (Precursor) GN=CPLX4 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: complexin-4 [Equus caballus] 
ENSG00000166573(GALR1)	--	0.0064916	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04230|0|hsa:2587|GALR1, GALNR, GALNR1; galanin receptor 1; K04230 galanin receptor 1 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srw;; Serpentine type 7TM GPCR chemoreceptor Srv	Galanin receptor type 1 GN=GALR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: galanin receptor type 1 [Equus caballus]
ENSG00000166575(TMEM135)	--	15.31316064	680	16.56679957	738	13.28615346	571	10.96169219	521	16.12591717	687	15.41822458	695	0.681402916	-0.414011303	normal	0.967840262	-0.124472836	normal	0.914280458	0.274570657	normal	0.809572548	-0.084443245	normal	--	--	--	--	--	[S]	Function unknown	Tim17/Tim22/Tim23/Pmp24 family	Transmembrane protein 135 GN=TMEM135 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 135 isoform X1 [Galeopterus variegatus]
ENSG00000166578(IQCD)	--	3.79219228	145	3.84213104	143	2.615944074	102	1.809355149	67	2.005112	78	2.151672	84	0.00187698	-1.126640931	down	0.058462755	-0.883053113	normal	0.949266225	-0.283755944	normal	0.025752459	-0.789189313	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	IQ calmodulin-binding motif	IQ domain-containing protein D GN=IQCD OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: IQ domain-containing protein D [Galeopterus variegatus]
ENSG00000166579(NDEL1)	--	19.783883	737	21.793062	799	19.69027209	727	20.785872	767	19.6782116	733	21.055005	765	0.975928863	0.026675184	normal	0.965764739	-0.145521184	normal	0.974440582	0.065080956	normal	0.956592571	-0.020054468	normal	--	--	--	K16739|0|tup:102503281|NDEL1; nudE neurodevelopment protein 1-like 1; K16739 nuclear distribution protein NudE-like 1 (A)	--	[Z]	Cytoskeleton	"NUDE protein, C-terminal conserved region"	Nuclear distribution protein nudE-like 1 GN=NDEL1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: nuclear distribution protein nudE-like 1 [Camelus bactrianus]
ENSG00000166582(CENPV)	--	57.224	1074	58.3408	1128	57.8842	1135	61.2386	1170	61.0335	1147	49.3805	939	0.977613356	0.092555396	normal	0.980587358	0.002668218	normal	0.919408768	-0.281373844	normal	0.83152856	-0.057199085	normal	[S]	Function unknown	Biological Process: metabolic process (GO:0008152);; Molecular Function: carbon-sulfur lyase activity (GO:0016846);; 	--	--	[S]	Function unknown	Glutathione-dependent formaldehyde-activating enzyme	Centromere protein V GN=CENPV OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein V [Oryctolagus cuniculus]
ENSG00000166589(CDH16)	--	0.159473038	1	0	0	0	0	0.018987062	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06810|0|ptr:454148|CDH16; cadherin 16, KSP-cadherin; K06810 cadherin 16, KSP-cadherin (A)"	--	[S]	Function unknown	Cadherin domain	Cadherin-16 (Precursor) GN=CDH16 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cadherin-16 isoform 1 [Ceratotherium simum simum]
ENSG00000166592(RRAD)	--	1.961360362	49	1.258613418	34	1.796095408	47	6.242600996	157	5.17776325	131	2.606711174	68	3.36E-07	1.619203658	up	4.93E-08	1.878887853	up	0.914149203	0.510845792	normal	0.019668393	1.430265121	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07845|2.7504e-171|nle:100604971|RRAD; Ras-related associated with diabetes; K07845 Ras-related associated with diabetes (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein	GTP-binding protein RAD GN=RRAD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: GTP-binding protein RAD [Myotis lucifugus]
ENSG00000166595(FAM96B)	--	90.76135244	724	88.73116416	730	105.9000011	879	104.3804547	851	92.94060604	745	87.22450398	705	0.953398618	0.201941578	normal	0.9754286	0.007901201	normal	0.866950612	-0.325903933	normal	0.894142912	-0.041364844	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Domain of unknown function DUF59	Mitotic spindle-associated MMXD complex subunit MIP18 GN=FAM96B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitotic spindle-associated MMXD complex subunit MIP18 [Ochotona princeps]
ENSG00000166596(CFAP52)	--	0.025100494	1	0	0	0.252732038	1	0.261698948	5	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Cilia- and flagella-associated protein 52 {ECO:0000312|HGNC:HGNC:16053} OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: WD repeat-containing protein 16 isoformX2 [Canis lupus familiaris]
ENSG00000166598(HSP90B1)	--	302.151854	18286	296.2807737	17545	312.8250432	18032	347.5514104	21186	308.3099723	18773	318.463862	19107	0.99574301	0.18152526	normal	0.997317786	0.076166364	normal	0.997469805	0.075244284	normal	0.666596379	0.111511626	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: protein folding (GO:0006457);; Biological Process: response to stress (GO:0006950);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K09487|0|nle:100599149|HSP90B1; heat shock protein 90kDa beta (Grp94), member 1; K09487 heat shock protein 90kDa beta (A)"	Protein processing in endoplasmic reticulum (ko04141);; PI3K-Akt signaling pathway (ko04151);; NOD-like receptor signaling pathway (ko04621);; Estrogen signaling pathway (ko04915);; Thyroid hormone synthesis (ko04918);; Pathways in cancer (ko05200);; Prostate cancer (ko05215)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Hsp90 protein;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase;; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase"	Endoplasmin (Precursor) GN=HSP90B1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: endoplasmin [Tupaia chinensis] 
ENSG00000166603(MC4R)	--	0.158936	4	0.0796094	2	0.078835	1	0	0	0.0772837	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04202|0|pps:100980364|MC4R; melanocortin 4 receptor; K04202 melanocortin 4 receptor (A)	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Melanocortin receptor 4 GN=MC4R OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: melanocortin receptor 4 [Ceratotherium simum simum]
ENSG00000166619(BLCAP)	--	22.98895584	608	24.5657735	652	24.21410447	673	33.92145276	907	29.79068154	795	30.55581951	849	0.19173055	0.545064542	normal	0.923789152	0.264100828	normal	0.865843761	0.326212578	normal	0.031807658	0.378884779	normal	--	--	--	--	--	[S]	Function unknown	Bladder cancer-related protein BC10	Bladder cancer-associated protein GN=BLCAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: bladder cancer-associated protein isoform X1 [Elephantulus edwardii] 
ENSG00000166664(CHRFAM7A)	--	5.266357076	179	2.70977873	137	4.593797	179	3.498019323	129	2.725587203	134	4.161601251	158	0.715374173	-0.498356967	normal	0.966298441	-0.052780326	normal	0.953546804	-0.186646888	normal	0.524441549	-0.253914028	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	CHRNA7-FAM7A fusion protein GN=CHRFAM7A OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuronal acetylcholine receptor subunit alpha-7 [Canis lupus familiaris]
ENSG00000166669(ATF7IP2)	--	7.956311046	121	5.207323234	126	8.02143924	118	8.062772171	141	5.888306816	121	4.406379291	118	0.95729871	0.187647096	normal	0.965999473	-0.078877082	normal	0.969372357	-0.008186524	normal	0.959921389	0.036240525	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	--	Activating transcription factor 7-interacting protein 2 GN=ATF7IP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: activating transcription factor 7-interacting protein 2 isoform X1 [Galeopterus variegatus] 
ENSG00000166670(MMP10)	--	0.06413448	2	0	0	0	0	0.06401676	2	0.0308266	0	0.219293216	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K01396|0|hsa:4319|MMP10, SL-2, STMY2; matrix metallopeptidase 10 (stromelysin 2) (EC:3.4.24.22); K01396 matrix metalloproteinase-10 (stromelysin 2) [EC:3.4.24.22] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	Stromelysin-2 (Precursor) GN=MMP10 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: stromelysin-2 [Loxodonta africana]
ENSG00000166676(TVP23A)	--	0.60058927	31	0.280440103	14	0.397689681	19	0.604620177	30	0.704601229	35	0.398121924	20	0.984720994	-0.074389786	normal	0.621942439	1.215032357	normal	0.988910859	0.060978196	normal	0.641539133	0.387176973	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Eukaryotic protein of unknown function (DUF846)	Golgi apparatus membrane protein TVP23 homolog A GN=TVP23A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: Golgi apparatus membrane protein TVP23 homolog A [Bubalus bubalis]
ENSG00000166681(BEX3)	--	141.25006	2258	137.72627	2322	149.47693	2516	159.29006	2617	159.04781	2524	151.63667	2451	0.978011154	0.181921119	normal	0.985794842	0.098855617	normal	0.988278992	-0.046024851	normal	0.747209522	0.076252327	normal	--	--	--	K12465|5.91307e-42|pps:100987914|protein BEX3; K12465 nerve growth factor receptor-associated protein 1 (A)	Neurotrophin signaling pathway (ko04722)	--	--	Brain expressed X-linked like family	Protein BEX3 GN=NGFRAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein BEX3 isoform X1 [Galeopterus variegatus] 
ENSG00000166682(TMPRSS5)	--	0.06696612	2	0	0	0.0253233	0	0.094777258	3	0.075023246	1	0.034099236	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K09636|0|pps:100981325|TMPRSS5; transmembrane protease, serine 5; K09636 transmembrane protease, serine 5 (spinesin) [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Scavenger receptor cysteine-rich domain	Transmembrane protease serine 5 GN=TMPRSS5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 5 [Orycteropus afer afer]
ENSG00000166685(COG1)	--	10.188324	631	9.116574866	584	8.49833	545	9.729036074	625	9.899463	631	9.22582	601	0.973310268	-0.044507187	normal	0.969505724	0.090020786	normal	0.96459416	0.132467166	normal	0.857800023	0.055935988	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Vps51/Vps67	Conserved oligomeric Golgi complex subunit 1 GN=COG1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: conserved oligomeric Golgi complex subunit 1 [Ceratotherium simum simum]
ENSG00000166689(PLEKHA7)	--	4.620451287	518	5.340001242	610	5.230741834	598	9.836224518	1035	10.7798777	1067	8.193815949	944	5.00E-06	0.965710111	normal	0.001200288	0.783765201	normal	0.02718629	0.649032529	normal	1.61E-07	0.798135223	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	--	--	PH domain;; Pleckstrin homology domain;; WW domain	Pleckstrin homology domain-containing family A member 7 GN=PLEKHA7 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: pleckstrin homology domain-containing family A member 7 [Sus scrofa]
ENSG00000166704(ZNF606)	--	4.955626159	212	5.498453372	230	4.493248493	211	4.320275312	187	3.788444031	189	5.127460463	196	0.946430166	-0.210234574	normal	0.908117035	-0.30247625	normal	0.961868125	-0.11383405	normal	0.555175939	-0.212214288	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:80095|ZNF606, ZNF328; zinc finger protein 606; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 606 GN=ZNF606 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: uncharacterized protein LOC101363436 [Odobenus rosmarus divergens]
ENSG00000166707(ZCCHC18)	--	0.036746973	2	0.017716903	1	0.017694827	0	0.124294453	7	0.592966358	13	0.138825	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PNMA	Putative zinc finger CCHC domain-containing protein 18 GN=ZCCHC18 OS=Homo sapiens (Human) PE=5 SV=1	K	Transcription	PREDICTED: putative zinc finger CCHC domain-containing protein 18 [Ceratotherium simum simum]
ENSG00000166710(B2M)	--	132.53175	3025	115.993666	2665	123.881629	2706	239.61381	5378	235.45238	5184	214.26217	4851	0.000278088	0.798994095	normal	3.67E-06	0.938115188	normal	8.76E-05	0.833476146	normal	5.04E-10	0.854820449	normal	--	--	--	K08055|1.40091e-72|ptr:450170|B2M; beta-2-microglobulin; K08055 beta-2-microglobulin (A)	Antigen processing and presentation (ko04612)	--	--	Immunoglobulin C1-set domain	Beta-2-microglobulin form pI 5.3 (Precursor) GN=B2M OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: beta-2-microglobulin [Dasypus novemcinctus]
ENSG00000166716(ZNF592)	--	11.90223907	1973	11.54579561	1916	11.0397225	1837	9.274776222	1527	10.25922824	1682	12.12535769	2008	0.748016756	-0.400167811	normal	0.967217261	-0.209170056	normal	0.982150544	0.120021668	normal	0.429435303	-0.154765887	normal	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type"	Zinc finger protein 592 GN=ZNF592 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 592 isoform X1 [Galeopterus variegatus] 
ENSG00000166734(CASC4)	--	36.10058105	2274	34.33331677	2183	36.07019881	2262	39.47162207	2488	34.75163693	2196	36.30917043	2340	0.985920025	0.0988581	normal	0.987321033	-0.012851757	normal	0.987731568	0.040591476	normal	0.874611439	0.042657536	normal	--	--	--	--	--	--	--	--	Protein CASC4 GN=CASC4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein CASC4 isoform X1 [Ailuropoda melanoleuca]
ENSG00000166736(HTR3A)	--	0.047967795	2	0	0	0	0	0.110444699	4	0.138664544	5	0.05449758	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04819|0|mcf:102126027|HTR3A; 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic; K04819 5-hydroxytryptamine receptor 3 (A)"	Serotonergic synapse (ko04726)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	5-hydroxytryptamine receptor 3A (Precursor) GN=HTR3A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: 5-hydroxytryptamine receptor 3A isoform X2 [Pantholops hodgsonii]
ENSG00000166741(NNMT)	--	22.00810605	603	13.53209519	383	19.50344401	535	70.78711856	1959	75.82964129	2080	106.3987848	2954	0	1.66656618	up	0	2.415153821	up	0	2.453447463	up	1.49E-08	2.181169491	up	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	K00541|0|hsa:4837|NNMT; nicotinamide N-methyltransferase (EC:2.1.1.1); K00541 nicotinamide N-methyltransferase [EC:2.1.1.1] (A)	Nicotinate and nicotinamide metabolism (ko00760)	--	--	NNMT/PNMT/TEMT family;; Methyltransferase domain	Nicotinamide N-methyltransferase GN=NNMT OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nicotinamide N-methyltransferase-like [Balaenoptera acutorostrata scammoni]
ENSG00000166747(AP1G1)	--	28.9756987	3018	32.25414752	3230	32.5487252	3153	33.98492333	3395	33.50423547	3437	32.49159115	3322	0.986258096	0.138919801	normal	0.989812575	0.068158191	normal	0.989887844	0.067004149	normal	0.695122811	0.089925468	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K12391|0|ptr:454228|AP1G1; adaptor-related protein complex 1, gamma 1 subunit; K12391 AP-1 complex subunit gamma-1 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptin N terminal region;; Adaptin C-terminal domain	AP-1 complex subunit gamma-1 GN=AP1G1 OS=Homo sapiens (Human) PE=1 SV=5	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-1 complex subunit gamma-1 isoform X1 [Oryctolagus cuniculus]
ENSG00000166750(SLFN5)	--	7.578578	1090	4.70230612	691	5.864920016	802	11.6161807	1595	10.60781625	1564	13.90841036	1859	0.261454122	0.517789443	normal	3.62E-09	1.15533044	up	1.64E-10	1.203027657	up	3.54E-06	0.93722727	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	Divergent AAA domain;; Uncharacterized conserved protein (DUF2075)	Schlafen family member 5 GN=SLFN5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: schlafen family member 5 [Leptonychotes weddellii]
ENSG00000166762(CATSPER2)	--	4.699799215	11	0.144203746	7	0.04536576	2	0.083402293	5	2.891895177	13	0.117751817	7	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K16890|0|hsa:117155|CATSPER2; cation channel, sperm associated 2; K16890 cation channel sperm-associated protein 2 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein	Cation channel sperm-associated protein 2 GN=CATSPER2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: cation channel sperm-associated protein 2 [Galeopterus variegatus]
ENSG00000166783(KIAA0430)	--	12.89457213	1372	10.32278559	1303	13.26420459	1339	8.089277105	1086	8.998358052	1085	14.61456688	1616	0.809078847	-0.367624673	normal	0.92169168	-0.28520527	normal	0.941752872	0.262709339	normal	0.793319535	-0.103979405	normal	--	--	--	K17573|0|ptr:454336|KIAA0430 ortholog; K17573 meiosis arrest female protein 1 (A)	--	--	--	"OST-HTH/LOTUS domain;; Limkain b1;; NYN domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Meiosis arrest female protein 1 GN=KIAA0430 OS=Homo sapiens (Human) PE=1 SV=6	R	General function prediction only	PREDICTED: meiosis arrest female protein 1 isoform X3 [Canis lupus familiaris]
ENSG00000166788(SAAL1)	--	20.28099491	559	18.391401	508	20.0043114	545	19.57618272	539	19.07894521	519	17.37760734	464	0.969532843	-0.08316247	normal	0.971290827	0.009451647	normal	0.932597709	-0.239701186	normal	0.715986195	-0.104444332	normal	--	--	--	--	--	--	--	--	Protein SAAL1 GN=SAAL1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	hypothetical protein PANDA_018864 [Ailuropoda melanoleuca]
ENSG00000166793(YPEL4)	--	0.607910452	41	0.545967	40	0.321114	26	0.159401	13	0.249976164	20	0.2346179	14	0.08639248	-1.577669544	normal	0.76711614	-0.968660712	normal	0.947350776	-0.834324042	normal	0.04068552	-1.208382721	normal	--	--	--	--	--	[R]	General function prediction only	"Yippee zinc-binding/DNA-binding /Mis18, centromere assembly"	Protein yippee-like 4 GN=YPEL4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: protein yippee-like 4 isoform X1 [Myotis brandtii] 
ENSG00000166794(PPIB)	--	340.52	5852	364.12	6460	340.931	6077	473.365	8510	445.502	7652	469.469	8209	0.4652926	0.509285644	normal	0.985852678	0.222828175	normal	0.816600612	0.425464325	normal	0.019738605	0.384937402	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	K03768|1.98899e-142|pon:100456537|PPIB; peptidylprolyl isomerase B (cyclophilin B); K03768 peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase B (Precursor) GN=PPIB OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase B [Galeopterus variegatus]
ENSG00000166796(LDHC)	--	0.073913336	2	0	0	0.112555487	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00016|0|ptr:451064|LDHC; lactate dehydrogenase C; K00016 L-lactate dehydrogenase [EC:1.1.1.27] (A)	Glycolysis / Gluconeogenesis (ko00010);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640)	[C]	Energy production and conversion	"lactate/malate dehydrogenase, NAD binding domain;; lactate/malate dehydrogenase, alpha/beta C-terminal domain"	L-lactate dehydrogenase C chain GN=LDHC OS=Homo sapiens (Human) PE=1 SV=4	C	Energy production and conversion	PREDICTED: L-lactate dehydrogenase C chain isoform 1 [Ceratotherium simum simum]
ENSG00000166797(FAM96A)	--	68.73514204	1101	65.71227228	1082	72.30178	1144	86.9213553	1405	75.08014	1195	75.29765	1215	0.887150837	0.320526639	normal	0.97474111	0.121721633	normal	0.979261781	0.078477143	normal	0.370199981	0.175863318	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Domain of unknown function DUF59	MIP18 family protein FAM96A GN=FAM96A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	MIP18 family protein FAM96A precursor [Bos taurus] 
ENSG00000166800(LDHAL6A)	--	0.0768633	3	0	0	0.200557	7	0.0779814	2	0.15072048	5	0.101680973	4	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00016|0|pps:100990051|LDHAL6A; lactate dehydrogenase A-like 6A; K00016 L-lactate dehydrogenase [EC:1.1.1.27] (A)	Glycolysis / Gluconeogenesis (ko00010);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640)	[C]	Energy production and conversion	"lactate/malate dehydrogenase, NAD binding domain;; lactate/malate dehydrogenase, alpha/beta C-terminal domain"	L-lactate dehydrogenase A-like 6A GN=LDHAL6A OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: L-lactate dehydrogenase A-like 6A [Ursus maritimus]
ENSG00000166801(FAM111A)	--	13.04506455	918	16.09825939	1070	13.43637727	978	15.502516	1075	12.621813	876	17.048163	1357	0.959170516	0.196633989	normal	0.893695991	-0.309550136	normal	0.488087226	0.463611692	normal	0.725058255	0.136822671	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Trypsin-like peptidase domain;; Trypsin	Protein FAM111A GN=FAM111A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM111A [Ceratotherium simum simum]
ENSG00000166803(PCLAF)	--	235.0692547	1880	225.8117011	1889	251.507578	1891	270.6951299	2122	220.8587003	1797	250.0048408	1854	0.980331365	0.14374911	normal	0.983209663	-0.09338219	normal	0.98591059	-0.036769863	normal	0.985016047	0.00686475	normal	--	--	--	--	--	--	--	--	PCNA-associated factor GN=KIAA0101 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PCNA-associated factor [Camelus ferus]
ENSG00000166813(KIF7)	--	4.07784	404	3.82612	395	3.78786	395	2.90655	291	3.62844	358	2.18211	217	0.462802586	-0.501908047	normal	0.954456527	-0.162665127	normal	0.00134201	-0.867898101	normal	0.028452026	-0.485168068	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K18806|0|hsa:374654|KIF7, ACLS, HLS2, JBTS12, UNQ340; kinesin family member 7; K18806 kinesin family member 7 (A)"	--	--	--	Kinesin motor domain	Kinesin-like protein KIF7 GN=KIF7 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF7 [Orcinus orca]
ENSG00000166816(LDHD)	--	1.378043012	63	1.389609451	59	0.981186735	50	0.975616046	40	1.253361	54	1.053165149	47	0.841272477	-0.665631012	normal	0.973409847	-0.14528795	normal	0.978295934	-0.094606895	normal	0.635096483	-0.307660491	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00102|0|hsa:197257|LDHD, DLD; lactate dehydrogenase D (EC:1.1.2.4); K00102 D-lactate dehydrogenase (cytochrome) [EC:1.1.2.4] (A)"	Pyruvate metabolism (ko00620)	[C]	Energy production and conversion	"FAD linked oxidases, C-terminal domain;; FAD binding domain"	"Probable D-lactate dehydrogenase, mitochondrial (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: probable D-lactate dehydrogenase, mitochondrial isoform X1 [Equus caballus] "
ENSG00000166819(PLIN1)	--	0.136350059	7	0.096012327	5	0.14390659	5	0.058521862	3	0.018890601	0	0.096352007	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08768|0|hsa:5346|PLIN1, FPLD4, PERI, PLIN; perilipin 1; K08768 perilipin (A)"	PPAR signaling pathway (ko03320)	--	--	Perilipin family	Perilipin-1 GN=PLIN1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: perilipin-1 [Camelus dromedarius]
ENSG00000166821(PEX11A)	--	5.491889925	185	4.488923048	191	3.729069263	166	2.994177759	135	3.833776536	126	3.246090527	122	0.738888675	-0.480703152	normal	0.400979032	-0.615529592	normal	0.814394904	-0.447815603	normal	0.103917932	-0.522678823	normal	--	--	Cellular Component: integral component of peroxisomal membrane (GO:0005779);; Biological Process: peroxisome fission (GO:0016559);; 	K13351|8.87608e-144|ggo:101145909|PEX11A; peroxisomal membrane protein 11A isoform 1; K13351 peroxin-11A (A)	Peroxisome (ko04146)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Peroxisomal biogenesis factor 11 (PEX11)	Peroxisomal membrane protein 11A GN=PEX11A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein 11A isoform 1 [Ceratotherium simum simum]
ENSG00000166823(MESP1)	--	6.871976	126	5.342531	98	7.49468	144	6.255025	111	5.053979	95	4.276467	76	0.955706787	-0.210953304	normal	0.968944183	-0.065257928	normal	0.037254265	-0.916811514	normal	0.329270712	-0.405810514	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09076|8.82077e-124|hsa:55897|MESP1, bHLHc5; mesoderm posterior basic helix-loop-helix transcription factor 1; K09076 mesoderm posterior (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Mesoderm posterior protein 1 GN=MESP1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: mesoderm posterior protein 1 [Felis catus]
ENSG00000166825(ANPEP)	--	6.26558	498	1.63051	131	5.8532	483	9.0197396	669	5.256548007	417	4.404089001	324	0.73825487	0.39397626	normal	9.81E-13	1.637878239	up	0.174080527	-0.58208049	normal	0.762208716	0.320046559	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	"K11140|0|hsa:290|ANPEP, APN, CD13, GP150, LAP1, P150, PEPN; alanyl (membrane) aminopeptidase (EC:3.4.11.2); K11140 aminopeptidase N [EC:3.4.11.2] (A)"	Glutathione metabolism (ko00480);; Renin-angiotensin system (ko04614);; Hematopoietic cell lineage (ko04640)	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	Aminopeptidase N GN=ANPEP OS=Homo sapiens (Human) PE=1 SV=4	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: aminopeptidase N [Tupaia chinensis] 
ENSG00000166828(SCNN1G)	--	0	0	0	0	0	0	0.0134811	1	0.0130671	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	"K04827|0|hsa:6340|SCNN1G, BESC3, ENaCg, ENaCgamma, PHA1, SCNEG; sodium channel, non-voltage-gated 1, gamma subunit; K04827 amiloride-sensitive sodium channel subunit gamma (A)"	Taste transduction (ko04742);; Aldosterone-regulated sodium reabsorption (ko04960)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Amiloride-sensitive sodium channel subunit gamma GN=SCNN1G OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: amiloride-sensitive sodium channel subunit gamma [Tupaia chinensis]
ENSG00000166831(RBPMS2)	--	10.38622002	320	7.932009161	238	10.99916594	336	5.004411046	153	6.390031024	196	4.033596025	125	2.47E-05	-1.087640323	down	0.908563166	-0.299434149	normal	3.54E-09	-1.423885815	down	0.00066172	-0.936534205	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein with multiple splicing 2 GN=RBPMS2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein with multiple splicing 2 [Tupaia chinensis]
ENSG00000166833(NAV2)	--	2.410281126	411	1.908033101	419	2.094814556	427	7.519847442	1559	6.400529722	1261	5.703255546	1179	0	1.888688808	up	2.22E-16	1.564702364	up	2.35E-14	1.453733076	up	1.27E-16	1.647605655	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Calponin homology (CH) domain	Neuron navigator 2 GN=NAV2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: neuron navigator 2 isoform X1 [Orycteropus afer afer]
ENSG00000166839(ANKDD1A)	--	9.702793846	525	8.66870877	463	9.387167229	519	5.977092324	342	6.475294277	347	6.215872648	332	0.05463871	-0.646788517	normal	0.660796972	-0.435852428	normal	0.053397666	-0.650452903	normal	0.002750843	-0.582841304	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Death domain;; Putative binding domain	Ankyrin repeat and death domain-containing protein 1A GN=ANKDD1A OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: LOW QUALITY PROTEIN: ankyrin repeat and death domain-containing protein 1A [Equus przewalskii]
ENSG00000166840(GLYATL1)	--	0.069945487	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: mitochondrion (GO:0005739);; Molecular Function: glycine N-acyltransferase activity (GO:0047961);; 	--	--	--	--	"Aralkyl acyl-CoA:amino acid N-acyltransferase;; Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region"	Glycine N-acyltransferase-like protein 1 GN=GLYATL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: glycine N-acyltransferase-like protein 1 [Trichechus manatus latirostris]
ENSG00000166845(C18orf54)	--	3.138060758	275	3.074391483	274	3.996490941	338	3.234969551	285	2.416426338	215	2.967322503	263	0.967324741	0.020585066	normal	0.843007062	-0.368960682	normal	0.827764191	-0.368378319	normal	0.420584226	-0.238430313	normal	--	--	--	--	--	--	--	--	Lung adenoma susceptibility protein 2 (Precursor) GN=LAS2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: lung adenoma susceptibility protein 2 isoform X1 [Equus caballus] 
ENSG00000166847(DCTN5)	--	11.649086	1422	14.78552706	1557	15.69123714	1532	16.25264875	2048	17.17589406	2056	19.56840773	2008	0.363124805	0.495014136	normal	0.814572873	0.379323228	normal	0.799052549	0.381721438	normal	0.005689341	0.416991276	normal	--	--	--	K10427|1.15409e-117|tup:102495152|DCTN5; dynactin 5 (p25); K10427 dynactin 5 (A)	Vasopressin-regulated water reabsorption (ko04962)	[Z]	Cytoskeleton	Bacterial transferase hexapeptide (six repeats)	Dynactin subunit 5 GN=DCTN5 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	dynactin subunit 5 [Bos taurus] 
ENSG00000166848(TERF2IP)	--	15.03050015	582	18.25490017	725	18.22900013	719	20.9988608	824	20.54410013	793	20.4571339	792	0.474484664	0.469746137	normal	0.970645563	0.107698467	normal	0.968352115	0.130954689	normal	0.25909667	0.228613719	normal	--	--	--	"K11113|0|hsa:54386|TERF2IP, DRIP5, RAP1; telomeric repeat binding factor 2, interacting protein; K11113 telomeric repeat-binding factor 2-interacting protein 1 (A)"	--	--	--	Rap1 Myb domain;; TRF2-interacting telomeric protein/Rap1 - C terminal domain	Telomeric repeat-binding factor 2-interacting protein 1 GN=TERF2IP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: telomeric repeat-binding factor 2-interacting protein 1 [Sus scrofa]
ENSG00000166851(PLK1)	--	58.98972084	2477	52.79200318	2238	55.2566368	2357	54.93756465	2275	58.42188703	2435	46.60473727	1964	0.981491929	-0.153460218	normal	0.985350774	0.100220242	normal	0.948192419	-0.271257328	normal	0.632235429	-0.105086869	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K06631|0|pon:100437332|PLK1; polo-like kinase 1; K06631 polo-like kinase 1 [EC:2.7.11.21] (A)	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; POLO box duplicated region;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase PLK1 GN=PLK1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase PLK1 [Galeopterus variegatus]
ENSG00000166855(CLPX)	--	17.575321	1385	17.348883	1377	16.794656	1310	18.76775716	1492	18.25458	1440	18.3458	1449	0.981678585	0.07644758	normal	0.982392307	0.043067441	normal	0.976090666	0.137048853	normal	0.721808438	0.084145343	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	"Molecular Function: ATP binding (GO:0005524);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transcription factor binding (GO:0008134);; Molecular Function: ATPase activity (GO:0016887);; "	K03544|0|hsa:10845|CLPX; caseinolytic mitochondrial matrix peptidase chaperone subunit; K03544 ATP-dependent Clp protease ATP-binding subunit ClpX (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"AAA domain (Cdc48 subfamily);; C-terminal, D2-small domain, of ClpB protein;; ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily);; Sigma-54 interaction domain;; Magnesium chelatase, subunit ChlI"	"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (Precursor) GN=CLPX OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial [Sus scrofa]"
ENSG00000166856(GPR182)	--	0	0	0	0	0.1540807	5	0	0	0.03841485	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04242|0|ggo:101127457|GPR182; G-protein coupled receptor 182; K04242 adrenomedullin receptor (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 182 GN=GPR182 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 182 [Pteropus alecto] 
ENSG00000166860(ZBTB39)	--	3.09848	358	3.06556	354	2.46364	282	3.20846	368	3.60936	413	3.16047	364	0.968914727	0.008876343	normal	0.945255715	0.200173542	normal	0.837041044	0.358256466	normal	0.525432489	0.182477435	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10511|0|hsa:9880|ZBTB39, ZNF922; zinc finger and BTB domain containing 39; K10511 zinc finger and BTB domain-containing protein 39 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type"	Zinc finger and BTB domain-containing protein 39 GN=ZBTB39 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 39 [Vicugna pacos]
ENSG00000166863(TAC3)	--	0.131793254	4	0.025852647	2	0.064304798	4	0.026361832	2	0	0	0.017475975	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: tachykinin receptor signaling pathway (GO:0007217);; 	K05240|2.34941e-83|pps:100992350|TAC3; tachykinin 3; K05240 tachykinin 2/3 (A)	--	--	--	Neurokinin B	Neurokinin-B (Precursor) GN=TAC3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tachykinin-3 isoform X2 [Canis lupus familiaris]
ENSG00000166881(NEMP1)	--	17.24833	1454	19.66254525	1660	19.481804	1613	17.37972	1474	13.329969	1117	21.345069	1800	0.983752851	-0.011111347	normal	0.080190557	-0.592318178	normal	0.977484529	0.149825992	normal	0.733955685	-0.127020089	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2215)	Transmembrane protein 194A GN=TMEM194A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 194A isoform X1 [Bubalus bubalis]
ENSG00000166886(NAB2)	--	6.66151	380	6.2508	364	5.94696	342	4.3421	245	5.50667	309	5.76547	328	0.073993762	-0.660693979	normal	0.923061095	-0.256599602	normal	0.966431446	-0.068283605	normal	0.201218012	-0.320596715	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	--	--	[K]	Transcription	NAB conserved region 2 (NCD2);; NAB conserved region 1 (NCD1)	NGFI-A-binding protein 2 GN=NAB2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: NGFI-A-binding protein 2 [Camelus dromedarius]
ENSG00000166887(VPS39)	--	13.05548304	1304	11.92611848	1197	12.39411669	1237	11.42613324	1137	12.67552796	1254	13.29372086	1327	0.952825848	-0.22825557	normal	0.980728633	0.045631312	normal	0.979334186	0.092921729	normal	0.92086387	-0.02844854	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	CNH domain;; Vacuolar sorting protein 39 domain 2;; Vacuolar sorting protein 39 domain 1;; Region in Clathrin and VPS	Vam6/Vps39-like protein GN=VPS39 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vam6/Vps39-like protein [Camelus ferus]
ENSG00000166888(STAT6)	--	27.23052454	2255	29.54022466	2425	27.0833678	2256	30.10586652	2521	30.82804724	2605	30.99909371	2607	0.983816071	0.129952654	normal	0.986965119	0.08182283	normal	0.974759043	0.200207127	normal	0.508742812	0.13576915	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K11225|0|hsa:6778|STAT6, D12S1644, IL-4-STAT, STAT6B, STAT6C; signal transducer and activator of transcription 6, interleukin-4 induced; K11225 signal transducer and activator of transcription 6 (A)"	Jak-STAT signaling pathway (ko04630);; Hepatitis B (ko05161);; Inflammatory bowel disease (IBD) (ko05321)	[KT]	Transcription;; Signal transduction mechanisms	"STAT6 C-terminal;; STAT protein, DNA binding domain;; STAT protein, all-alpha domain;; STAT protein, protein interaction domain;; SH2 domain"	Signal transducer and activator of transcription 6 GN=STAT6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	signal transducer and activator of transcription 6 isoform 2 [Sus scrofa] 
ENSG00000166889(PATL1)	--	27.99009	2141	32.2323	2439	27.11065	2037	25.75807	1950	28.18243	2142	31.75812	2418	0.977924959	-0.165518409	normal	0.971897775	-0.208619689	normal	0.962856465	0.238913838	normal	0.869991257	-0.044288719	normal	--	--	--	"K12617|0|hsa:219988|PATL1, Pat1b, hPat1b; protein associated with topoisomerase II homolog 1 (yeast); K12617 DNA topoisomerase 2-associated protein PAT1 (A)"	RNA degradation (ko03018)	--	--	Topoisomerase II-associated protein PAT1	Protein PAT1 homolog 1 GN=PATL1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein PAT1 homolog 1 [Mustela putorius furo] 
ENSG00000166896(ATP23)	--	4.61216	82	4.459269081	82	5.304985	95	4.256926	78	5.981542	107	4.014888511	73	0.971566286	-0.101040572	normal	0.926509386	0.356714769	normal	0.92799212	-0.381376614	normal	0.980122653	-0.026491448	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; 	"K18156|0|hsa:91419|XRCC6BP1, KUB3; XRCC6 binding protein 1 (EC:3.4.24.-); K18156 mitochondrial inner membrane protease ATP23 [EC:3.4.24.-] (A)"	--	[L]	"Replication, recombination and repair"	Peptidase M76 family	Mitochondrial inner membrane protease ATP23 homolog GN=XRCC6BP1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: mitochondrial inner membrane protease ATP23 homolog [Lipotes vexillifer]
ENSG00000166897(ELFN2)	--	3.16948927	625	2.510185696	488	3.439247198	688	4.847973286	921	4.152230492	799	3.47703	670	0.245584597	0.527438664	normal	0.016544163	0.688205248	normal	0.974231991	-0.046435476	normal	0.13687273	0.386507022	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17568|0|hsa:114794|ELFN2, LRRC62, PPP1R29; extracellular leucine-rich repeat and fibronectin type III domain containing 2; K17568 protein phosphatase 1 regulatory subunit 29 (A)"	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat	Protein phosphatase 1 regulatory subunit 29 (Precursor) GN=ELFN2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein phosphatase 1 regulatory subunit 29 [Trichechus manatus latirostris]
ENSG00000166900(STX3)	--	10.45882832	613	14.67341966	821	11.4103	642	14.95921626	878	18.46374291	1062	28.85689188	1636	0.402892245	0.486477971	normal	0.839991596	0.349335938	normal	6.95E-13	1.339188259	up	0.138478241	0.764959108	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K08486|0|hsa:6809|STX3, STX3A; syntaxin 3; K08486 syntaxin 1B/2/3 (A)"	SNARE interactions in vesicular transport (ko04130);; Synaptic vesicle cycle (ko04721)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Syntaxin;; SNARE domain;; Syntaxin-like protein	Syntaxin-3 GN=STX3 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-3 [Elephantulus edwardii]
ENSG00000166902(MRPL16)	--	31.342093	588	33.14885748	637	32.64880861	627	37.807256	731	37.59627	690	30.95791867	592	0.90835621	0.282559766	normal	0.970269699	0.093662748	normal	0.970179001	-0.090933955	normal	0.713453307	0.098491927	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02878|7.31259e-172|pon:100173293|MRPL16; mitochondrial ribosomal protein L16; K02878 large subunit ribosomal protein L16 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L16p/L10e	"39S ribosomal protein L16, mitochondrial (Precursor) GN=MRPL16 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L16, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000166908(PIP4K2C)	--	20.81762709	1071	22.58789551	1196	20.79490896	1093	17.28537482	913	18.64871407	976	21.84129393	1146	0.932053376	-0.260698375	normal	0.892170684	-0.314250171	normal	0.979604232	0.059941201	normal	0.408150727	-0.167360172	normal	--	--	Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; 	"K00920|0|hsa:79837|PIP4K2C, PIP5K2C; phosphatidylinositol-5-phosphate 4-kinase, type II, gamma (EC:2.7.1.149); K00920 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	Phosphatidylinositol-4-phosphate 5-Kinase	Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma GN=PIP4K2C OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	Kinesin heavy chain isoform 5A [Tupaia chinensis]
ENSG00000166912(MTMR10)	--	8.694986	709	8.45072	706	8.456222	693	9.030102	723	9.339584	754	9.1675228	759	0.975651261	-0.002616629	normal	0.973038739	0.0733178	normal	0.968928156	0.122697167	normal	0.82445739	0.063980975	normal	--	--	--	K18085|0|hsa:54893|MTMR10; myotubularin related protein 10; K18085 myotubularin-related protein 10/11/12 (A)	--	[R]	General function prediction only	Myotubularin-like phosphatase domain;; Myotubularin-associated protein	Myotubularin-related protein 10 GN=MTMR10 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: myotubularin-related protein 10 [Galeopterus variegatus]
ENSG00000166913(YWHAB)	--	131.0396523	6898	141.449135	7480	137.5351435	7175	161.9771066	8541	151.1620919	7919	140.7628889	7425	0.976930177	0.277339003	normal	0.994802822	0.060841477	normal	0.994960465	0.041112234	normal	0.5762306	0.12657876	normal	--	--	--	"K16197|2.24931e-170|ssc:100153160|YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; K16197 14-3-3 protein beta/theta/zeta (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; Hippo signaling pathway (ko04390);; Hepatitis B (ko05161);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein	"14-3-3 protein beta/alpha, N-terminally processed GN=YWHAB OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein beta/alpha [Tupaia chinensis]
ENSG00000166920(C15orf48)	--	32.81334001	297	30.0999	286	22.5569119	207	102.028272	946	53.47000003	497	84.38740033	777	0	1.635546329	up	0.006331529	0.772667737	normal	0	1.89233408	up	0.001593396	1.467941891	up	--	--	--	--	--	--	--	NADH-ubiquinone reductase complex 1 MLRQ subunit	Normal mucosa of esophagus-specific gene 1 protein GN=NMES1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: normal mucosa of esophagus-specific gene 1 protein [Vicugna pacos]
ENSG00000166922(SCG5)	--	0.442524069	7	0.514050925	7	0.263265464	4	1.369596379	25	2.503133423	38	3.276975226	56	0.56874456	1.609101167	normal	0.004578851	2.195570189	up	1.42E-08	3.376102304	up	0.000430332	2.705168307	up	--	--	Biological Process: neuropeptide signaling pathway (GO:0007218);; Cellular Component: secretory granule (GO:0030141);; 	--	--	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Neuroendocrine protein 7B2 precursor (Secretogranin V)	C-terminal peptide (Precursor) GN=SCG5 OS=Homo sapiens (Human) PE=1 SV=2	OU	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Neuroendocrine protein 7B2 [Tupaia chinensis]
ENSG00000166923(GREM1)	--	12.1828382	989	27.57669114	2286	12.48363441	998	22.74880077	1753	21.90849628	1711	29.77844279	2376	0.00040713	0.794013079	normal	0.643131645	-0.439075168	normal	1.65E-11	1.241874056	up	0.548354514	0.429427422	normal	--	--	--	--	--	--	--	DAN domain	Gremlin-1 (Precursor) GN=GREM1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: gremlin-1 isoform X1 [Ursus maritimus]
ENSG00000166924(NYAP1)	--	1.929442023	155	2.223598614	176	2.500455236	204	0.544174025	38	0.375385048	29	0.70274646	56	1.74E-10	-2.015324561	down	4.44E-16	-2.561260949	down	6.70E-11	-1.845434436	down	4.27E-12	-2.140580948	down	--	--	--	--	--	--	--	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter;; Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter	Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 GN=NYAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 1 isoform X2 [Ailuropoda melanoleuca]
ENSG00000166925(TSC22D4)	--	32.56380099	1239	29.69093	1230	29.82939544	1283	23.00722983	918	17.484047	751	25.202526	1044	0.487945448	-0.462772857	normal	0.003711456	-0.732035849	normal	0.901778923	-0.305291238	normal	0.001420594	-0.488585325	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	TSC-22/dip/bun family	TSC22 domain family protein 4 GN=TSC22D4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: TSC22 domain family protein 4 isoform X2 [Galeopterus variegatus]
ENSG00000166927(MS4A7)	--	0	0	0	0	0	0	0	0	0.046359145	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	CD20-like family	Membrane-spanning 4-domains subfamily A member 7 GN=MS4A7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: membrane-spanning 4-domains subfamily A member 7 [Galeopterus variegatus]
ENSG00000166938(DIS3L)	--	19.77536926	1450	19.6316503	1467	20.89908878	1550	19.65255902	1493	20.10923301	1533	20.34036363	1542	0.98380354	0.011317184	normal	0.983114058	0.042019893	normal	0.984316085	-0.015741494	normal	0.975510055	0.011282798	normal	[K]	Transcription	--	K18681|0|nle:100607354|DIS3L; DIS3 mitotic control homolog (S. cerevisiae)-like; K18681 DIS3-like exonuclease 1 [EC:3.1.13.-] (A)	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	RNB domain	DIS3-like exonuclease 1 GN=DIS3L OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: DIS3-like exonuclease 1 isoform X1 [Pteropus alecto] 
ENSG00000166946(CCNDBP1)	--	6.894513	394	6.51124439	373	6.500494907	369	6.58218778	380	7.280355296	414	7.0285268	401	0.966279248	-0.082700056	normal	0.960597532	0.12853378	normal	0.963581504	0.111252492	normal	0.890790288	0.051996763	normal	--	--	--	--	--	--	--	Grap2 and cyclin-D-interacting	Cyclin-D1-binding protein 1 GN=CCNDBP1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cyclin-D1-binding protein 1 [Galeopterus variegatus]
ENSG00000166947(EPB42)	--	0.023394642	2	0.092486897	8	0.13758761	11	0.116681755	10	0.056506113	4	0.069626841	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein-glutamine gamma-glutamyltransferase activity (GO:0003810);; Biological Process: peptide cross-linking (GO:0018149);; 	--	--	--	--	"Transglutaminase family, C-terminal ig like domain;; Transglutaminase family;; Transglutaminase-like superfamily"	Erythrocyte membrane protein band 4.2 GN=EPB42 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: erythrocyte membrane protein band 4.2 isoform X1 [Galeopterus variegatus]
ENSG00000166949(SMAD3)	--	75.66850116	7440	81.52542865	8163	83.98387364	7999	88.02386264	8791	70.23477602	6916	77.1224179	7771	0.98880462	0.209852498	normal	0.980627775	-0.260535638	normal	0.995186106	-0.050001241	normal	0.925004422	-0.029243663	normal	--	--	"Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04500|0|tup:102473158|SMAD3; SMAD family member 3; K04500 mothers against decapentaplegic homolog 2/3 (A)	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Chagas disease (American trypanosomiasis) (ko05142);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Inflammatory bowel disease (IBD) (ko05321)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain;; Interferon-regulatory factor 3	Mothers against decapentaplegic homolog 3 GN=SMAD3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	mothers against decapentaplegic homolog 3 [Bos taurus] 
ENSG00000166963(MAP1A)	--	0.7438614	212	0.655103786	186	0.9112906	260	0.2819534	79	0.358573944	101	0.4037672	115	2.81E-07	-1.437195505	down	0.01820759	-0.892370394	normal	1.52E-05	-1.174610276	down	1.18E-05	-1.176896075	down	--	--	--	K10429|0|ggo:101150682|MAP1A; LOW QUALITY PROTEIN: microtubule-associated protein 1A; K10429 microtubule-associated protein 1 (A)	--	[Z]	Cytoskeleton	--	MAP1 light chain LC2 GN=MAP1A OS=Homo sapiens (Human) PE=1 SV=6	Z	Cytoskeleton	PREDICTED: microtubule-associated protein 1A isoform X1 [Galeopterus variegatus]
ENSG00000166965(RCCD1)	--	29.00409004	1279	27.67661244	1280	28.76994489	1300	20.96927328	945	19.95408373	886	24.56388296	1096	0.470937544	-0.466807082	normal	0.17330704	-0.551403972	normal	0.940726571	-0.254232753	normal	0.007329791	-0.419556284	normal	--	--	--	--	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat	RCC1 domain-containing protein 1 GN=RCCD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RCC1 domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000166971(AKTIP)	--	16.5719606	572	17.04834518	545	19.4096	595	18.881848	626	14.14137304	488	16.155325	531	0.96908209	0.099060854	normal	0.953253396	-0.180272674	normal	0.956947641	-0.172006199	normal	0.791022202	-0.079266937	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	AKT-interacting protein GN=AKTIP OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: AKT-interacting protein isoform X1 [Capra hircus]
ENSG00000166974(MAPRE2)	--	7.499635332	436	9.000112316	479	8.379373396	445	9.055386004	521	9.637903021	535	7.789819404	479	0.938260976	0.225395651	normal	0.961638449	0.137675245	normal	0.966584744	0.097609093	normal	0.564613796	0.153161399	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: protein binding (GO:0005515);; Molecular Function: microtubule binding (GO:0008017);; 	"K10436|0|hgl:101705572|Mapre2; microtubule-associated protein, RP/EB family, member 2; K10436 microtubule-associated protein, RP/EB family (A)"	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	EB1-like C-terminal motif;; Calponin homology (CH) domain	Microtubule-associated protein RP/EB family member 2 GN=MAPRE2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	microtubule-associated protein RP/EB family member 2 [Bos taurus] 
ENSG00000166979(EVA1C)	--	40.18153402	1321	22.529315	744	37.54568554	1245	10.66048989	354	13.13638694	426	12.81521227	431	0	-1.925985753	down	0.000758889	-0.823633171	normal	3.33E-16	-1.535355994	down	0.000471689	-1.470738396	down	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	--	--	[R]	General function prediction only	FAM176 family;; Galactose binding lectin domain	Protein eva-1 homolog C (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	protein eva-1 homolog C [Bos taurus] 
ENSG00000166986(MARS)	--	89.47847901	4685	83.800565	4413	88.3532	4669	71.061207	3199	62.191029	3220	94.40782	4851	0.106645839	-0.581028169	normal	0.562137891	-0.47593382	normal	0.992829387	0.046862257	normal	0.283074701	-0.308615534	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01874|0|hsa:4141|MARS, METRS, MRS, MTRNS, SPG70; methionyl-tRNA synthetase (EC:6.1.1.10); K01874 methionyl-tRNA synthetase [EC:6.1.1.10] (A)"	Selenocompound metabolism (ko00450);; Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (M);; WHEP-TRS domain;; tRNA synthetases class I (I, L, M and V);; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain"	"Methionine--tRNA ligase, cytoplasmic GN=MARS OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: methionine--tRNA ligase, cytoplasmic isoform X2 [Felis catus]"
ENSG00000166987(MBD6)	--	14.464579	895	18.170212	1079	17.86428043	1029	14.47536605	984	15.878124	1004	24.683571	1611	0.974153438	0.105765176	normal	0.973103048	-0.125180218	normal	0.025881317	0.637666976	normal	0.635125073	0.241518007	normal	--	--	--	--	--	--	--	--	Methyl-CpG-binding domain protein 6 GN=MBD6 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: methyl-CpG-binding domain protein 6 [Myotis davidii]
ENSG00000166997(CNPY4)	--	7.550343	236	7.372918	239	6.669072	222	7.34646	221	8.26049	248	6.238018	203	0.960389337	-0.124733356	normal	0.965621367	0.031705998	normal	0.959223557	-0.136399355	normal	0.867890036	-0.074169645	normal	--	--	--	--	--	[S]	Function unknown	TLR4 regulator and MIR-interacting MSAP	Protein canopy homolog 4 (Precursor) GN=CNPY4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: protein canopy homolog 4 [Ursus maritimus]
ENSG00000167004(PDIA3)	--	108.3192548	6992	107.0818889	6911	105.9348399	6748	131.604864	8560	123.4010382	7936	116.7323604	7543	0.980870055	0.26102144	normal	0.990539315	0.178054607	normal	0.991944182	0.152354701	normal	0.320407317	0.197535203	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	"K08056|0|ptr:742723|PDIA3; protein disulfide isomerase family A, member 3 (EC:5.3.4.1); K08056 protein disulfide isomerase family A, member 3 [EC:5.3.4.1] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Antigen processing and presentation (ko04612)	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like domain;; Thioredoxin-like;; Thioredoxin-like;; Thioredoxin;; AhpC/TSA family	Protein disulfide-isomerase A3 (Precursor) GN=PDIA3 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein disulfide-isomerase A3 isoform 1 [Ceratotherium simum simum]
ENSG00000167005(NUDT21)	--	32.680014	2064	37.10724	2238	40.83341	2189	40.63711529	2625	36.61151508	2327	35.41270636	2258	0.919115182	0.315833303	normal	0.987437027	0.034811548	normal	0.987507576	0.03645729	normal	0.530077875	0.129898098	normal	--	--	Molecular Function: mRNA binding (GO:0003729);; Cellular Component: mRNA cleavage factor complex (GO:0005849);; Biological Process: mRNA polyadenylation (GO:0006378);; 	K14397|8.56677e-167|ptr:454100|NUDT21; nudix (nucleoside diphosphate linked moiety X)-type motif 21; K14397 cleavage and polyadenylation specificity factor subunit 5 (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Nucleotide hydrolase	Cleavage and polyadenylation specificity factor subunit 5 GN=NUDT21 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	cleavage and polyadenylation specificity factor subunit 5 [Sus scrofa]
ENSG00000167011(NAT16)	--	0.043610706	2	0.021219145	1	0	0	0.045553722	2	0.042169268	1	0.021391539	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative N-acetyltransferase 16 GN=NAT16 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: putative N-acetyltransferase 16 [Orycteropus afer afer]
ENSG00000167034(NKX3-1)	--	3.51352898	152	2.762724821	161	2.67575014	155	7.513120142	437	6.641521947	383	5.502866633	318	4.75E-11	1.483491404	up	4.37E-07	1.221196157	up	0.000128362	1.021363722	up	2.01E-09	1.259754596	up	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09348|2.00706e-102|pps:100967944|NKX3-1; NK3 homeobox 1; K09348 homeobox protein Nkx-3.1 (A)	Pathways in cancer (ko05200);; Prostate cancer (ko05215)	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-3.1 GN=NKX3-1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox protein Nkx-3.1 [Loxodonta africana]
ENSG00000167037(SGSM1)	--	0.48700525	65	0.424029647	55	0.315078993	42	0.132203265	18	0.169011765	23	0.265615111	37	0.000452194	-1.797239366	down	0.161698235	-1.225538425	normal	0.979011431	-0.184088607	normal	0.034591765	-1.074044765	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	RUN domain;; Rab-GTPase-TBC domain	Small G protein signaling modulator 1 GN=SGSM1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: small G protein signaling modulator 1 isoform X1 [Sus scrofa]
ENSG00000167065(DUSP18)	--	4.0413178	202	4.470875	223	4.9565401	276	2.732635	165	2.569899	130	2.827462	174	0.905294356	-0.320022827	normal	0.040443846	-0.792828	normal	0.125336408	-0.669212741	normal	0.028365163	-0.60049339	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14165|2.85721e-139|ptr:458760|DUSP18; dual specificity phosphatase 18; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain"	Dual specificity protein phosphatase 18 GN=DUSP18 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 18 [Ceratotherium simum simum]
ENSG00000167074(TEF)	--	2.317624163	184	1.724493641	141	1.850314297	151	1.097250501	88	1.62514288	129	1.314618695	102	0.000857518	-1.081595455	down	0.960060195	-0.148089411	normal	0.638782953	-0.567313209	normal	0.072940774	-0.59810122	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09058|2.84804e-155|mcc:707009|TEF; thyrotrophic embryonic factor; K09058 thyrotrophic embryonic factor (A)	--	[K]	Transcription	Basic region leucine zipper;; bZIP transcription factor	Thyrotroph embryonic factor GN=TEF OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: thyrotroph embryonic factor isoform X1 [Mustela putorius furo]
ENSG00000167077(MEI1)	--	0.024215037	1	0.041145781	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Meiosis inhibitor protein 1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: meiosis inhibitor protein 1 [Ursus maritimus]
ENSG00000167080(B4GALNT2)	--	0.707353498	42	0.145022349	14	0.3660238	29	1.115365811	82	0.487822621	41	0.344392751	36	0.315322088	0.910176978	normal	0.196569841	1.434467568	normal	0.978575781	0.290054059	normal	0.339702192	0.879754297	normal	--	--	--	"K09655|0|hsa:124872|B4GALNT2, B4GALT, GALGT2; beta-1,4-N-acetyl-galactosaminyl transferase 2 (EC:2.4.1.-); K09655 beta-1,4-N-acetylgalactosaminyltransferase 2 [EC:2.4.1.-] (A)"	--	--	--	Glycosyl transferase family 2	"Beta-1,4 N-acetylgalactosaminyltransferase 2 GN=B4GALNT2 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: beta-1,4 N-acetylgalactosaminyltransferase 2 isoform X2 [Galeopterus variegatus]"
ENSG00000167081(PBX3)	--	9.79146207	402	8.813401559	443	9.710170692	485	9.391739643	478	9.1467017	442	8.294430893	359	0.940519492	0.218217295	normal	0.969559799	-0.024602806	normal	0.633697823	-0.440688974	normal	0.81388952	-0.078187322	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K15610|0|shr:100924707|pre-B-cell leukemia transcription factor 3-like; K15610 pre-B-cell leukemia transcription factor 3 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	PBC domain;; Homeobox domain;; Homeobox KN domain	Pre-B-cell leukemia transcription factor 3 GN=PBX3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: pre-B-cell leukemia transcription factor 3 isoform 1 [Orcinus orca] 
ENSG00000167083(GNGT2)	--	0	0	0.192148396	3	0.118027	1	0.307263671	5	0.0829252	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04549|5.09682e-37|ptr:749133|GNGT2; guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; K04549 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 (Precursor) GN=GNGT2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 isoform X1 [Equus caballus] 
ENSG00000167085(PHB)	--	181.7259775	4695	190.4007448	4987	208.1869575	5354	190.0133378	5159	182.8750559	4816	180.0808451	4826	0.991643541	0.105101208	normal	0.992343258	-0.071741229	normal	0.989096712	-0.158033626	normal	0.874691735	-0.043963837	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K17080|0|ptr:455205|PHB; prohibitin; K17080 prohibitin 1 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPFH domain / Band 7 family	Prohibitin GN=PHB OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	Prohibitin [Myotis brandtii]
ENSG00000167088(SNRPD1)	--	20.00358229	1034	19.11088614	1134	19.4345321	1076	25.4686836	1357	21.86432365	1161	16.48975003	947	0.821945879	0.360882972	normal	0.980636	0.012504294	normal	0.960823838	-0.192244967	normal	0.812287628	0.072783142	normal	[K]	Transcription	--	K11087|1.56555e-62|pbi:103064956|small nuclear ribonucleoprotein Sm D1-like; K11087 small nuclear ribonucleoprotein D1 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	Small nuclear ribonucleoprotein Sm D1 GN=SNRPD1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: small nuclear ribonucleoprotein Sm D1-like [Odobenus rosmarus divergens]
ENSG00000167094(TTC16)	--	0.0296802	2	0.014752	1	0.014263	0	0	0	0.0287675	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 16 GN=TTC16 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: tetratricopeptide repeat protein 16 [Galeopterus variegatus]
ENSG00000167100(SAMD14)	--	2.102723	181	1.949248	174	1.515287672	136	1.564129	135	1.769802153	153	1.82000553	157	0.794066121	-0.449427387	normal	0.949001299	-0.205079857	normal	0.953861297	0.196827843	normal	0.715334529	-0.163070406	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Sterile alpha motif domain-containing protein 14 GN=SAMD14 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: sterile alpha motif domain-containing protein 14 [Trichechus manatus latirostris]
ENSG00000167103(PIP5KL1)	--	1.895108917	65	1.3828794	54	1.321551	49	0.623630797	24	1.213993277	48	1.3711438	51	0.015710446	-1.411134889	normal	0.97340045	-0.185828028	normal	0.978577945	0.047972732	normal	0.42419064	-0.46914373	normal	--	--	Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; 	"K13712|0|hsa:138429|PIP5KL1, PIPKH, bA203J24.5; phosphatidylinositol-4-phosphate 5-kinase-like 1 (EC:2.7.1.68); K13712 phosphatidylinositol-4-phosphate 5-kinase-like protein 1 [EC:2.7.1.68] (A)"	Inositol phosphate metabolism (ko00562);; Endocytosis (ko04144)	[T]	Signal transduction mechanisms	Phosphatidylinositol-4-phosphate 5-Kinase	Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 GN=PIP5KL1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-phosphate 5-kinase-like protein 1 [Odobenus rosmarus divergens]
ENSG00000167105(TMEM92)	--	13.52016879	212	7.742358	149	7.507507989	201	15.3082935	332	13.09517093	306	9.002814455	220	0.190844767	0.612711679	normal	0.000250218	1.009496546	up	0.961024928	0.121145101	normal	0.054769901	0.588344578	normal	--	--	--	--	--	--	--	--	Transmembrane protein 92 (Precursor) GN=TMEM92 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 92 [Galeopterus variegatus]
ENSG00000167107(ACSF2)	--	12.07762308	608	10.391007	495	9.8572726	498	10.35369928	524	15.04327152	735	9.370637987	475	0.930921731	-0.244669991	normal	0.221281342	0.54750824	normal	0.968912656	-0.076272484	normal	0.845389714	0.09375481	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K00666|0|hsa:80221|ACSF2, ACSMW, AVYV493; acyl-CoA synthetase family member 2 (EC:6.2.1.-); K00666 fatty-acyl-CoA synthase [EC:6.2.1.-] (A)"	--	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	"Acyl-CoA synthetase family member 2, mitochondrial (Precursor) GN=ACSF2 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: acyl-CoA synthetase family member 2, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000167110(GOLGA2)	--	23.47048595	1692	23.3177445	1690	22.44866531	1710	19.26321603	1397	18.4043789	1373	20.58000552	1566	0.910156879	-0.306922519	normal	0.898205337	-0.320799046	normal	0.978687883	-0.135078677	normal	0.141850332	-0.252712072	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 2 GN=GOLGA2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X2 [Galeopterus variegatus]
ENSG00000167112(TRUB2)	--	8.682531013	999	9.805790757	1134	9.736193146	1121	10.26450127	1178	10.75270121	1230	11.33183305	1306	0.957880526	0.206657759	normal	0.97764391	0.09568857	normal	0.95860312	0.211812205	normal	0.396281904	0.169949855	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: RNA processing (GO:0006396);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	TruB family pseudouridylate synthase (N terminal domain)	Probable tRNA pseudouridine synthase 2 GN=TRUB2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: probable tRNA pseudouridine synthase 2 [Panthera tigris altaica]
ENSG00000167113(COQ4)	--	30.14488	496	29.26581	506	35.011125	592	30.41684	568	32.01913	546	32.28014	570	0.957833622	0.164242873	normal	0.968000253	0.088083546	normal	0.971668673	-0.06276329	normal	0.85721208	0.058349017	normal	[H]	Coenzyme transport and metabolism	Biological Process: ubiquinone biosynthetic process (GO:0006744);; 	"K18586|0|hsa:51117|COQ4, CGI-92; coenzyme Q4; K18586 ubiquinone biosynthesis protein COQ4 (A)"	--	[H]	Coenzyme transport and metabolism	Coenzyme Q (ubiquinone) biosynthesis protein Coq4	"Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03111} (Precursor) OS=Homo sapiens (Human) PE=2 SV=3"	H	Coenzyme transport and metabolism	"PREDICTED: ubiquinone biosynthesis protein COQ4 homolog, mitochondrial [Galeopterus variegatus]"
ENSG00000167114(SLC27A4)	--	17.436224	1076	18.052143	1073	19.538716	1136	20.841934	1242	18.771438	1147	19.3953529	1166	0.966935522	0.175920883	normal	0.978251315	0.074686937	normal	0.980916687	0.029275044	normal	0.695192068	0.092652788	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K08745|0|hsa:10999|SLC27A4, ACSVL4, FATP4, IPS; solute carrier family 27 (fatty acid transporter), member 4 (EC:6.2.1.-); K08745 solute carrier family 27 (fatty acid transporter), member 1/4 [EC:6.2.1.-] (A)"	PPAR signaling pathway (ko03320);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	Long-chain fatty acid transport protein 4 GN=SLC27A4 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: long-chain fatty acid transport protein 4 [Galeopterus variegatus]
ENSG00000167118(URM1)	--	23.37184621	1157	24.73777079	1254	26.56702834	1327	26.21335028	1299	25.32506119	1236	23.22511679	1158	0.974477716	0.136009788	normal	0.981019936	-0.04223386	normal	0.961268375	-0.204574779	normal	0.891433938	-0.03884669	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Cellular Component: cytoplasm (GO:0005737);; Biological Process: tRNA thio-modification (GO:0034227);; 	"K12161|7.26864e-80|hsa:81605|URM1, C9orf74; ubiquitin related modifier 1; K12161 ubiquitin related modifier 1 (A)"	Sulfur relay system (ko04122)	[O]	"Posttranslational modification, protein turnover, chaperones"	Urm1 (Ubiquitin related modifier)	Ubiquitin-related modifier 1 {ECO:0000255|HAMAP-Rule:MF_03048} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-related modifier 1 homolog isoform X2 [Canis lupus familiaris]
ENSG00000167123(CERCAM)	--	31.92777879	1457	30.64913988	1285	31.0898002	1375	32.169493	1385	34.989018	1485	26.89904275	1135	0.979748731	-0.103834838	normal	0.967500293	0.187063086	normal	0.922458129	-0.284685577	normal	0.812661443	-0.061432649	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyltransferase family 25 (LPS biosynthesis protein);; Glycosyl transferase family 2	Probable inactive glycosyltransferase 25 family member 3 (Precursor) GN=CERCAM OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable inactive glycosyltransferase 25 family member 3 [Galeopterus variegatus]
ENSG00000167130(DOLPP1)	--	10.40653	392	10.86555	415	10.49761	402	12.74085	482	13.07931	491	11.78905	447	0.917017073	0.266404268	normal	0.939426163	0.220445895	normal	0.959662337	0.144272977	normal	0.401274226	0.21067539	normal	[I]	Lipid transport and metabolism	--	K07252|4.77566e-163|pps:100984250|DOLPP1; dolichyldiphosphatase 1; K07252 dolichyldiphosphatase [EC:3.6.1.43] (A)	N-Glycan biosynthesis (ko00510)	[I]	Lipid transport and metabolism	PAP2 superfamily	Dolichyldiphosphatase 1 GN=DOLPP1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: dolichyldiphosphatase 1 isoform 1 [Orcinus orca] 
ENSG00000167131(CCDC103)	--	7.873064	182	8.737098	201	8.262143	191	7.293795	161	6.97906	154	6.409748	159	0.949654649	-0.205860777	normal	0.836441829	-0.402223242	normal	0.930896802	-0.270486604	normal	0.400659459	-0.297431344	normal	--	--	--	--	--	--	--	Potential Monad-binding region of RPAP3	Coiled-coil domain-containing protein 103 GN=CCDC103 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 103-like isoform X1 [Equus caballus] 
ENSG00000167136(ENDOG)	--	14.04385	223	15.81181	251	14.91664	222	13.85808	232	19.67038	288	12.9897	217	0.966735491	0.026072716	normal	0.950835518	0.17596455	normal	0.966356916	-0.040874437	normal	0.891521873	0.061193791	normal	[F]	Nucleotide transport and metabolism	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; 	"K01173|9.22925e-174|pon:100452114|ENDOG; endonuclease G; K01173 endonuclease G, mitochondrial (A)"	Apoptosis (ko04210)	[F]	Nucleotide transport and metabolism	DNA/RNA non-specific endonuclease	"Endonuclease G, mitochondrial (Precursor) GN=ENDOG OS=Homo sapiens (Human) PE=1 SV=4"	F	Nucleotide transport and metabolism	"PREDICTED: endonuclease G, mitochondrial [Ochotona princeps]"
ENSG00000167157(PRRX2)	--	4.22065	82	2.4328	49	1.85407	38	0.554998	11	2.01398	39	0.34981	7	8.01E-10	-2.764934636	down	0.96626197	-0.338980738	normal	0.003548364	-2.222078866	down	0.074854729	-1.589781906	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09329|1.86098e-97|ptr:464792|PRRX2; paired related homeobox 2; K09329 paired mesoderm homeobox protein (A)	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Paired mesoderm homeobox protein 2 GN=PRRX2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: paired mesoderm homeobox protein 2 [Loxodonta africana]
ENSG00000167165(UGT1A6)	--	0.30671058	11	0.106156352	4	0.132809699	4	15.6368498	567	24.9726415	917	15.12270228	530	0	5.474148682	up	0	7.362036584	up	0	6.584165986	up	5.52E-19	6.706083852	up	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00699|0|hsa:54578|UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F; UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17); K00699 glucuronosyltransferase [EC:2.4.1.17] (A)"	Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Steroid hormone biosynthesis (ko00140);; Starch and sucrose metabolism (ko00500);; Retinol metabolism (ko00830);; Porphyrin and chlorophyll metabolism (ko00860);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain;; Glycosyl transferase family 1	UDP-glucuronosyltransferase 1-6 (Precursor) GN=UGT1A6 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronosyltransferase 1-6 isoform X2 [Galeopterus variegatus]
ENSG00000167173(C15orf39)	--	18.07168358	1542	19.55423646	1711	15.58572565	1363	16.63101611	1440	17.58558465	1512	19.38710127	1716	0.977995413	-0.129432721	normal	0.96744992	-0.199620344	normal	0.892285439	0.323651837	normal	0.989389689	-0.004831944	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C15orf39 GN=C15orf39 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C15orf39 homolog [Orycteropus afer afer]
ENSG00000167178(ISLR2)	--	0.087306984	5	0	0	0.019881467	0	0	0	0.27305827	9	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Immunoglobulin domain;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Immunoglobulin superfamily containing leucine-rich repeat protein 2 (Precursor) GN=ISLR2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily containing leucine-rich repeat protein 2 [Ceratotherium simum simum]
ENSG00000167182(SP2)	--	6.343033055	381	7.222710909	462	6.546341883	364	6.30934368	396	8.030134689	523	7.214068198	480	0.969186729	0.024779156	normal	0.957900781	0.157008269	normal	0.766682924	0.389391438	normal	0.478499688	0.192128691	normal	[R]	General function prediction only	--	K09192|0|pon:100443291|SP2; Sp2 transcription factor; K09192 transcription factor Sp2 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Transcription factor Sp2 GN=SP2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor Sp2 isoform X2 [Equus przewalskii]
ENSG00000167183(PRR15L)	--	0.0686445	2	0.0339049	1	0	0	0.170339	5	0.400903	11	0.135962	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	ATPase family AAA domain containing 4	Proline-rich protein 15-like protein GN=PRR15L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: proline-rich protein 15-like protein isoform 1 [Dasypus novemcinctus] 
ENSG00000167186(COQ7)	--	11.47326518	316	10.03194413	321	11.05313345	335	9.568066255	302	10.42206536	321	14.34708009	420	0.963807893	-0.095732069	normal	0.96705772	-0.021326089	normal	0.879143158	0.316657565	normal	0.824780737	0.08159374	normal	[H]	Coenzyme transport and metabolism	Biological Process: ubiquinone biosynthetic process (GO:0006744);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K06134|1.07346e-124|pps:100984081|COQ7; coenzyme Q7 homolog, ubiquinone (yeast); K06134 ubiquinone biosynthesis monooxygenase Coq7 [EC:1.14.13.-] (A)"	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130)	[R]	General function prediction only	Ubiquinone biosynthesis protein COQ7	Ubiquinone biosynthesis protein COQ7 homolog (Precursor) GN=COQ7 OS=Homo sapiens (Human) PE=1 SV=3	H	Coenzyme transport and metabolism	PREDICTED: ubiquinone biosynthesis protein COQ7 homolog [Camelus bactrianus]
ENSG00000167191(GPRC5B)	--	16.740891	1188	16.56171	1183	18.70126053	1292	15.954299	1189	16.846067	1177	19.963581	1522	0.981220744	-0.029580145	normal	0.980729514	-0.028725497	normal	0.956311566	0.227824897	normal	0.821676026	0.065691287	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04619|0|hsa:51704|GPRC5B, RAIG-2, RAIG2; G protein-coupled receptor, class C, group 5, member B; K04619 G protein-coupled receptor family C group 5 member B (A)"	--	--	--	7 transmembrane sweet-taste receptor of 3 GCPR	G-protein coupled receptor family C group 5 member B (Precursor) GN=GPRC5B OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor family C group 5 member B isoform X1 [Vicugna pacos]
ENSG00000167193(CRK)	--	50.62453642	3032	50.92798372	3217	47.30192761	2949	57.23276135	3527	53.32357991	3349	51.01308989	3091	0.981412775	0.187251522	normal	0.990347437	0.036571033	normal	0.989550632	0.059526571	normal	0.677082128	0.094144415	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K04438|0|ecb:100072356|CRK; v-crk avian sarcoma virus CT10 oncogene homolog; K04438 proto-oncogene C-crk (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Fc gamma R-mediated phagocytosis (ko04666);; Neurotrophin signaling pathway (ko04722);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Bacterial invasion of epithelial cells (ko05100);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Variant SH3 domain;; SH2 domain;; SH3 domain;; Variant SH3 domain	Adapter molecule crk GN=CRK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: adapter molecule crk [Equus caballus] 
ENSG00000167196(FBXO22)	--	41.80354366	2253	40.33169938	2661	45.66503983	2416	44.56821589	2210	31.32674006	1943	44.06549215	2275	0.98700793	-0.058592862	normal	0.504793875	-0.474791973	normal	0.985992878	-0.094984071	normal	0.238662756	-0.210669791	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K10302|0|pps:100977252|FBXO22; F-box protein 22; K10302 F-box protein 22 (A)	--	--	--	FIST C domain;; F-box domain	F-box only protein 22 GN=FBXO22 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box only protein 22 isoform X2 [Felis catus] 
ENSG00000167202(TBC1D2B)	--	8.629935	1012	9.428093	1116	9.888699	1165	12.46499	1457	12.124969	1413	12.80998	1501	0.355132964	0.494330799	normal	0.89286862	0.318613407	normal	0.83527483	0.35689339	normal	0.013874423	0.387590814	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	TBC1 domain family member 2B GN=TBC1D2B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: TBC1 domain family member 2B, partial [Ceratotherium simum simum]"
ENSG00000167207(NOD2)	--	0.01209053	1	0	0	0	0	0	0	0.047196971	3	0.01199102	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K10165|0|ptr:454083|NOD2, CARD15; nucleotide-binding oligomerization domain containing 2; K10165 nucleotide-binding oligomerization domain-containing protein 2 (A)"	NOD-like receptor signaling pathway (ko04621);; TNF signaling pathway (ko04668);; Tuberculosis (ko05152);; Inflammatory bowel disease (IBD) (ko05321)	[S]	Function unknown	NACHT domain;; Caspase recruitment domain;; Leucine Rich repeat;; Leucine Rich repeats (2 copies)	Nucleotide-binding oligomerization domain-containing protein 2 GN=NOD2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: nucleotide-binding oligomerization domain-containing protein 2 [Galeopterus variegatus]
ENSG00000167216(KATNAL2)	--	4.405831	101	4.716082	89	2.948867475	101	1.294327	66	3.035591004	60	1.5817258	77	0.696191089	-0.632648966	normal	0.811789413	-0.578223204	normal	0.919058939	-0.392956908	normal	0.215636647	-0.540175257	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; LisH;; Holliday junction DNA helicase ruvB N-terminus	Katanin p60 ATPase-containing subunit A-like 2 {ECO:0000255|HAMAP-Rule:MF_03025} OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: katanin p60 ATPase-containing subunit A-like 2 isoform X1 [Tupaia chinensis]
ENSG00000167220(HDHD2)	--	7.08142934	261	6.481420107	225	7.780308	267	8.425216183	259	6.382981187	233	7.739403235	260	0.966537332	-0.041683645	normal	0.965575008	0.028788254	normal	0.966461952	-0.046353493	normal	0.967635723	-0.022940963	normal	[G]	Carbohydrate transport and metabolism	--	--	--	[R]	General function prediction only	Haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase	Haloacid dehalogenase-like hydrolase domain-containing protein 2 GN=HDHD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: haloacid dehalogenase-like hydrolase domain-containing protein 2 isoform X1 [Tupaia chinensis] 
ENSG00000167232(ZNF91)	--	0.782521041	66	1.156723869	70	1.043298888	73	0.480514251	51	0.594231989	62	0.989743525	49	0.948836242	-0.392378187	normal	0.968128638	-0.192100335	normal	0.872959965	-0.568927152	normal	0.488552458	-0.388579871	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:469069|ZNF91; zinc finger protein 91; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; SprT-like family;; C1-like domain"	Zinc finger protein 91 GN=ZNF91 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000167244(IGF2)	--	1.070818073	77	0.556443115	43	0.896360956	75	1.709660969	214	2.538473912	268	0.922599683	93	4.42E-07	1.426076471	up	0	2.577073003	up	0.950543511	0.296667281	normal	0.055293365	1.537793562	normal	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K13769|5.93186e-125|aml:100483184|insulin-like growth factor II-like; K13769 insulin-like growth factor 2 (A)	Proteoglycans in cancer (ko05205)	--	--	Insulin-like growth factor II E-peptide;; Insulin/IGF/Relaxin family	Preptin (Precursor) GN=IGF2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: insulin-like growth factor II isoform X5 [Camelus bactrianus] 
ENSG00000167257(RNF214)	--	6.0055315	275	4.598285096	253	7.0502738	259	3.490654901	199	4.413254	246	7.467227	317	0.593909244	-0.494233609	normal	0.964522483	-0.061532606	normal	0.912184298	0.281749915	normal	0.880654591	-0.066378406	normal	--	--	--	--	--	--	--	--	RING finger protein 214 GN=RNF214 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 214 [Galeopterus variegatus]
ENSG00000167258(CDK12)	--	23.42765791	3333	28.2996761	3927	25.53356599	3494	20.3746333	2841	22.53486087	3177	22.58910691	3188	0.962546383	-0.261124196	normal	0.929826443	-0.327048744	normal	0.98654603	-0.140455753	normal	0.157559097	-0.245142449	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08819|0|ggo:101137348|CDK12; cyclin-dependent kinase 12 isoform 1; K08819 cyclin-dependent kinase 12/13 [EC:2.7.11.22 2.7.11.23] (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 12 GN=CDK12 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 12 isoform X1 [Ursus maritimus]
ENSG00000167264(DUS2)	--	10.41411788	438	7.922842376	334	11.41934989	453	12.50669314	461	12.32113301	517	9.219889735	386	0.96988402	0.042857078	normal	0.12405608	0.606665547	normal	0.932230484	-0.238338709	normal	0.680962758	0.133822733	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: tRNA processing (GO:0008033);; Molecular Function: tRNA dihydrouridine synthase activity (GO:0017150);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K05543|0|hsa:54920|DUS2, DUS2L, SMM1, URLC8; dihydrouridine synthase 2; K05543 tRNA-dihydrouridine synthase 2 [EC:1.3.1.91] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Dihydrouridine synthase (Dus);; Double-stranded RNA binding motif	tRNA-dihydrouridine(20) synthase [NAD(P)+]-like GN=DUS2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like isoform X2 [Panthera tigris altaica] 
ENSG00000167272(POP5)	--	27.91952	322	28.62051	336	29.11764	341	31.0491	368	35.16549	403	31.37892	367	0.955148641	0.161093442	normal	0.930656312	0.239904995	normal	0.964483725	0.097300855	normal	0.573132395	0.166853595	normal	--	--	Molecular Function: ribonuclease activity (GO:0004540);; Biological Process: tRNA processing (GO:0008033);; 	"K03537|1.34179e-91|pps:100967999|POP5; processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae); K03537 ribonuclease P/MRP protein subunit POP5 [EC:3.1.26.5] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Rpp14/Pop5 family	Ribonuclease P/MRP protein subunit POP5 GN=POP5 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ribonuclease P/MRP protein subunit POP5 [Loxodonta africana]
ENSG00000167280(ENGASE)	--	10.735758	865	7.8574521	733	9.752692	849	10.69356225	880	9.709094	845	10.96366	932	0.977944961	-0.006018274	normal	0.95845847	0.183359022	normal	0.971273626	0.126059579	normal	0.694632285	0.097888346	normal	[G]	Carbohydrate transport and metabolism	Cellular Component: cytoplasm (GO:0005737);; Molecular Function: mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity (GO:0033925);; 	K01227|0|hsa:64772|ENGASE; endo-beta-N-acetylglucosaminidase (EC:3.2.1.96); K01227 mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase [EC:3.2.1.96] (A)	Other glycan degradation (ko00511)	[R]	General function prediction only	Glycosyl hydrolase family 85	Cytosolic endo-beta-N-acetylglucosaminidase GN=ENGASE OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cytosolic endo-beta-N-acetylglucosaminidase [Galeopterus variegatus]
ENSG00000167281(RBFOX3)	--	25.45941847	443	8.946813397	201	11.1675633	311	4.54427491	107	10.63271986	234	6.16933137	129	0	-2.064682561	down	0.947382817	0.196515119	normal	4.32E-07	-1.267950611	down	0.128791223	-1.043129462	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K14946|0|mcf:101867210|uncharacterized LOC101867210; K14946 RNA binding protein fox-1 (A)	--	[R]	General function prediction only	"Calcitonin gene-related peptide regulator C terminal;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA binding protein fox-1 homolog 3 GN=RBFOX3 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: RNA binding protein fox-1 homolog 3 isoform X2 [Mustela putorius furo]
ENSG00000167291(TBC1D16)	--	14.64200745	2706	11.8260058	2364	13.52665858	2677	16.04120351	3096	19.35850036	3559	16.63901767	3007	0.982855068	0.163324628	normal	0.145291053	0.568517018	normal	0.983048764	0.159331317	normal	0.068967907	0.297619745	normal	[R]	General function prediction only	--	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 16 GN=TBC1D16 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: TBC1 domain family member 16 isoform X1 [Equus caballus]
ENSG00000167302(TEPSIN)	--	9.638321111	515	10.28734935	568	10.19315546	573	11.02169711	535	8.361105929	457	12.795891	652	0.97197302	0.02406376	normal	0.855364207	-0.334129347	normal	0.956658742	0.177605677	normal	0.935206041	-0.031066669	normal	--	--	--	--	--	--	--	ENTH domain	AP-4 complex accessory subunit tepsin GN=ENTHD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: AP-4 complex accessory subunit tepsin [Galeopterus variegatus]
ENSG00000167306(MYO5B)	--	4.334802815	201	3.57542706	169	4.263677357	212	8.138629685	388	7.696186978	377	5.868425542	288	0.000574649	0.91292215	normal	5.09E-06	1.129175678	up	0.741026445	0.431065057	normal	0.000128168	0.833698076	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	K10357|0|hsa:4645|MYO5B; myosin VB; K10357 myosin V (A)	--	[Z]	Cytoskeleton	Myosin head (motor domain);; DIL domain;; IQ calmodulin-binding motif	Unconventional myosin-Vb GN=MYO5B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: unconventional myosin-Vb-like isoform X3 [Tupaia chinensis]
ENSG00000167311(ART5)	--	0	0	0.181400401	2	0	0	0.089610315	1	0	0	0.054694102	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: NAD(P)+-protein-arginine ADP-ribosyltransferase activity (GO:0003956);; Biological Process: protein ADP-ribosylation (GO:0006471);; 	"K00775|0|hsa:116969|ART5, ARTC5; ADP-ribosyltransferase 5 (EC:2.4.2.31); K00775 NAD(P)-arginine ADP-ribosyltransferase [EC:2.4.2.31] (A)"	--	--	--	NAD:arginine ADP-ribosyltransferase	Ecto-ADP-ribosyltransferase 5 (Precursor) GN=ART5 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ecto-ADP-ribosyltransferase 5 isoform X2 [Oryctolagus cuniculus]
ENSG00000167315(ACAA2)	--	38.66172067	1450	31.65832003	1209	34.16429885	1285	38.17168095	1426	37.68228822	1439	36.56187239	1349	0.982642739	-0.054852571	normal	0.95436649	0.229562315	normal	0.981418607	0.061759603	normal	0.760492236	0.074174837	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	"K07508|0|hsa:10449|ACAA2, DSAEC; acetyl-CoA acyltransferase 2 (EC:2.3.1.16); K07508 acetyl-CoA acyltransferase 2 [EC:2.3.1.16] (A)"	"Fatty acid elongation (ko00062);; Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	"Thiolase, N-terminal domain;; Thiolase, C-terminal domain"	"3-ketoacyl-CoA thiolase, mitochondrial GN=ACAA2 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: 3-ketoacyl-CoA thiolase, mitochondrial-like [Tupaia chinensis]"
ENSG00000167323(STIM1)	--	42.31388588	2661	33.85437055	2327	41.09938844	2695	38.16246495	2407	36.82085602	2382	47.2405714	2547	0.979568643	-0.17545805	normal	0.987962061	0.012267765	normal	0.987308127	-0.089725956	normal	0.702729366	-0.087537252	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16059|0|hsa:6786|STIM1, D11S4896E, GOK, IMD10, STRMK, TAM, TAM1; stromal interaction molecule 1; K16059 stromal interaction molecule 1 (A)"	Calcium signaling pathway (ko04020);; Platelet activation (ko04611)	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Stromal interaction molecule 1 (Precursor) GN=STIM1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: stromal interaction molecule 1 isoform X1 [Tupaia chinensis]
ENSG00000167325(RRM1)	--	52.04160458	2971	53.91990347	3075	56.12330293	3161	66.65640484	3821	61.36220472	3484	54.33140318	3098	0.920541481	0.332017656	normal	0.984559191	0.158658315	normal	0.990260483	-0.037317299	normal	0.434044983	0.154451678	normal	[F]	Nucleotide transport and metabolism	"Molecular Function: ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor (GO:0004748);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication (GO:0006260);; Biological Process: oxidation-reduction process (GO:0055114);; "	K10807|0|ptr:450974|RRM1; ribonucleotide reductase M1; K10807 ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Glutathione metabolism (ko00480)	[F]	Nucleotide transport and metabolism	"Ribonucleotide reductase, barrel domain;; Ribonucleotide reductase, all-alpha domain;; ATP cone domain"	Ribonucleoside-diphosphate reductase large subunit GN=RRM1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: ribonucleoside-diphosphate reductase large subunit [Oryctolagus cuniculus]
ENSG00000167333(TRIM68)	--	4.760006983	309	5.083533815	344	4.076517153	267	4.435929683	285	4.447215	273	4.889818539	316	0.957312618	-0.146717261	normal	0.846474444	-0.353186937	normal	0.935196371	0.233575967	normal	0.793355372	-0.095278156	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12033|0|hsa:55128|TRIM68, GC109, RNF137, SS-56, SS56; tripartite motif containing 68; K12033 tripartite motif-containing protein 68 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	E3 ubiquitin-protein ligase TRIM68 GN=TRIM68 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM68 [Odobenus rosmarus divergens]
ENSG00000167363(FN3K)	--	16.129463	381	19.802795	479	15.63473	383	11.208186	268	11.8105558	280	16.9682802	405	0.363052081	-0.535799261	normal	0.004311495	-0.792710714	normal	0.967316011	0.072009544	normal	0.196941423	-0.40348666	normal	[G]	Carbohydrate transport and metabolism	--	K15522|0|hsa:64122|FN3K; fructosamine 3 kinase (EC:2.7.1.-); K15522 protein-fructosamine 3-kinase [EC:2.7.1.171] (A)	--	[R]	General function prediction only	Fructosamine kinase;; Phosphotransferase enzyme family	Fructosamine-3-kinase GN=FN3K OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: fructosamine-3-kinase [Felis catus]
ENSG00000167371(PRRT2)	--	1.760356423	87	3.046795966	117	1.976545264	94	1.75926968	98	1.870560795	102	2.61122144	138	0.967639606	0.138626578	normal	0.954756125	-0.216367947	normal	0.731844206	0.538453075	normal	0.769508119	0.161332611	normal	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced transmembrane protein	Proline-rich transmembrane protein 2 GN=PRRT2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: proline-rich transmembrane protein 2 [Camelus bactrianus]
ENSG00000167377(ZNF23)	--	4.092446819	236	3.871744829	222	3.533416845	205	3.900332901	208	2.873512247	167	3.55996063	191	0.944746813	-0.21156717	normal	0.787359533	-0.428758278	normal	0.962362106	-0.109505609	normal	0.468744001	-0.249933527	normal	[R]	General function prediction only	--	"K09228|0|hsa:7571|ZNF23, KOX16, ZNF359, ZNF612, Zfp612; zinc finger protein 23; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; NTF2 fold immunity protein;; Zinc ribbon domain;; TFIIH C1-like domain;; Transposase zinc-ribbon domain;; Rapsyn N-terminal myristoylation and linker region"	Zinc finger protein 23 GN=ZNF23 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 23 isoform X1 [Galeopterus variegatus] 
ENSG00000167380(ZNF226)	--	27.36072617	422	20.32636191	353	21.35818609	403	17.16846914	333	16.91683259	350	20.60270385	410	0.807256978	-0.371028236	normal	0.967374848	-0.033595279	normal	0.969811002	0.016491275	normal	0.674825578	-0.128506911	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7769|ZNF226; zinc finger protein 226; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; KRAB box;; Zinc-finger of C2H2 type;; XPA protein N-terminal;; Zinc ribbon domain"	Zinc finger protein 226 GN=ZNF226 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 226 [Lipotes vexillifer]
ENSG00000167384(ZNF180)	--	6.89441643	389	4.968034558	271	4.416455548	280	6.396183587	361	4.270746812	280	4.884372365	223	0.959649744	-0.138037426	normal	0.966172673	0.025567057	normal	0.87760253	-0.334644734	normal	0.786760681	-0.144506141	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100972840|ZNF180; zinc finger protein 180; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; XPA protein N-terminal;; CpXC protein;; Zinc-finger double-stranded RNA-binding;; GATA zinc finger;; Zinc ribbon domain"	Zinc finger protein 180 GN=ZNF180 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 180 isoform X2 [Galeopterus variegatus]
ENSG00000167393(PPP2R3B)	--	17.981829	821	16.90775687	826	17.887846	863	12.50212877	510	10.6079195	443	13.16620007	529	0.00682961	-0.715999701	normal	4.86E-05	-0.917927963	normal	0.007099917	-0.712772674	normal	1.05E-06	-0.781202801	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K11583|0|hsa:28227|PPP2R3B, NYREN8, PPP2R3L, PPP2R3LY, PR48; protein phosphatase 2, regulatory subunit B'', beta; K11583 serine/threonine-protein phosphatase 2A regulatory subunit B'' (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Dopaminergic synapse (ko04728)	[A]	RNA processing and modification	EF-hand domain pair;; EF hand	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta GN=PPP2R3B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_018852 [Ailuropoda melanoleuca]
ENSG00000167394(ZNF668)	--	10.21096304	460	10.93369909	504	8.888244807	413	7.406219532	345	8.831125148	407	8.605906725	399	0.627725038	-0.444150046	normal	0.863237103	-0.328721535	normal	0.968418407	-0.057829027	normal	0.231945514	-0.279639031	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger of C2H2 type"	Zinc finger protein 668 GN=ZNF668 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 668 isoform X4 [Canis lupus familiaris]
ENSG00000167395(ZNF646)	--	6.316781618	829	7.983110259	915	6.75880743	799	7.127893432	758	6.8186201	815	8.036379114	932	0.96414637	-0.15969684	normal	0.958829955	-0.188068664	normal	0.951430441	0.21346857	normal	0.886719891	-0.042462123	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein 646 GN=ZNF646 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 646 [Ceratotherium simum simum]
ENSG00000167419(LPO)	--	0	0	0	0	0	0	0	0	0	0	0.0219997	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K12550|0|pps:100993002|LPO; lactoperoxidase; K12550 lactoperoxidase [EC:1.11.1.7] (A)	Salivary secretion (ko04970)	[R]	General function prediction only	Animal haem peroxidase	Lactoperoxidase (Precursor) GN=LPO OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lactoperoxidase isoform X1 [Galeopterus variegatus]
ENSG00000167460(TPM4)	--	210.952708	11367	206.018929	11237	204.0033985	11069	329.7690595	17964	316.6362896	16961	229.0198277	12202	0.076105768	0.629356614	normal	0.286587808	0.57247463	normal	0.995192882	0.132284083	normal	0.055792567	0.462680652	normal	--	--	--	K10375|2.82636e-117|lve:103089632|TPM4; tropomyosin 4; K10375 tropomyosin 4 (A)	Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Tropomyosin;; Tropomyosin like;; Laminin Domain II	Tropomyosin alpha-1 chain GN=TPM1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tropomyosin alpha-4 chain isoform 2 [Orcinus orca] 
ENSG00000167461(RAB8A)	--	18.75589724	1037	18.47783	928	18.08529892	1010	24.32831444	1218	21.69870379	1178	17.51812273	923	0.960251331	0.200990986	normal	0.882016197	0.322249213	normal	0.970832952	-0.138027908	normal	0.533930739	0.135980503	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07901|6.75781e-151|ssc:100511006|RAB8A; RAB8A, member RAS oncogene family; K07901 Ras-related protein Rab-8A (A)"	AMPK signaling pathway (ko04152);; Pancreatic secretion (ko04972)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-8A (Precursor) GN=RAB8A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	ras-related protein Rab-8A [Bos taurus] 
ENSG00000167468(GPX4)	--	162.2248004	1954	154.2653219	1886	141.2317305	1744	129.6776247	1616	149.380685	1811	171.6687028	2105	0.918079938	-0.304571708	normal	0.983964264	-0.079904296	normal	0.949133952	0.262920944	normal	0.90236579	-0.034047198	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K05361|3.88658e-147|hsa:2879|GPX4, GPx-4, GSHPx-4, MCSP, PHGPx, snGPx, snPHGPx; glutathione peroxidase 4 (EC:1.11.1.12); K05361 phospholipid-hydroperoxide glutathione peroxidase [EC:1.11.1.12] (A)"	Glutathione metabolism (ko00480)	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"Phospholipid hydroperoxide glutathione peroxidase, mitochondrial (Precursor) GN=GPX4 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"phospholipid hydroperoxide glutathione peroxidase, mitochondrial precursor [Sus scrofa] "
ENSG00000167470(MIDN)	--	22.756301	1357	25.17844	1386	20.46026117	1277	23.28483009	1416	26.139932	1340	31.90758	1903	0.982911357	0.030534437	normal	0.981001155	-0.070043083	normal	0.115532395	0.566672323	normal	0.53588097	0.192365043	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ubiquitin family	Midnolin GN=MIDN OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: midnolin isoformX2 [Canis lupus familiaris]
ENSG00000167476(JSRP1)	--	0	0	0.0931337	2	0	0	0.0467006	1	0	0	0.0472454	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Junctional sarcoplasmic reticulum protein	Junctional sarcoplasmic reticulum protein 1 GN=JSRP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: junctional sarcoplasmic reticulum protein 1 [Lipotes vexillifer]
ENSG00000167483(FAM129C)	--	0.139943037	5	0.248331165	9	0.193898526	6	0.056126979	2	0.168680083	5	0.034130078	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Niban-like protein 2 GN=FAM129C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: niban-like protein 2 isoform X2 [Galeopterus variegatus]
ENSG00000167487(KLHL26)	--	3.34450552	259	3.300895247	182	2.864127562	227	4.289153003	235	3.690347398	271	2.21287748	173	0.953357774	-0.170063907	normal	0.449883437	0.54916579	normal	0.829157173	-0.397171201	normal	1	0.001813889	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10463|0|hsa:55295|KLHL26; kelch-like family member 26; K10463 kelch-like protein 26 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; BTB And C-terminal Kelch;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 26 GN=KLHL26 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 26 isoform X3 [Canis lupus familiaris]
ENSG00000167491(GATAD2A)	--	14.88852313	1335	14.92218476	1422	13.84187417	1471	19.94209223	1802	19.74980119	1735	14.8088303	1237	0.736658183	0.40152798	normal	0.942845819	0.265331826	normal	0.941952902	-0.257953613	normal	0.60577763	0.153125308	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[S]	Function unknown	--	Transcriptional repressor p66-alpha GN=GATAD2A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transcriptional repressor p66-alpha isoform X1 [Camelus ferus] 
ENSG00000167508(MVD)	--	47.8977	1487	43.18412	1378	52.65007	1666	16.50942	493	16.12226871	519	32.232057	992	0	-1.620514184	down	6.27E-14	-1.427537865	down	0.001245235	-0.755369048	normal	1.86E-05	-1.195725272	down	[I]	Lipid transport and metabolism	Molecular Function: ATP binding (GO:0005524);; 	"K01597|0|hsa:4597|MVD, FP17780, MDDase, MPD; mevalonate (diphospho) decarboxylase (EC:4.1.1.33); K01597 diphosphomevalonate decarboxylase [EC:4.1.1.33] (A)"	Terpenoid backbone biosynthesis (ko00900)	[I]	Lipid transport and metabolism	GHMP kinases N terminal domain	Diphosphomevalonate decarboxylase GN=MVD OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: diphosphomevalonate decarboxylase [Equus przewalskii]
ENSG00000167513(CDT1)	--	18.34127983	1061	14.8215097	910	18.49450978	1153	16.88782813	1008	15.62534136	941	15.09338517	920	0.975564445	-0.10460584	normal	0.977891864	0.026857728	normal	0.863577721	-0.333487428	normal	0.506549243	-0.144005886	normal	--	--	--	"K10727|0|hsa:81620|CDT1, DUP, RIS2; chromatin licensing and DNA replication factor 1; K10727 chromatin licensing and DNA replication factor 1 (A)"	--	[L]	"Replication, recombination and repair"	DNA replication factor CDT1 like	DNA replication factor Cdt1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA replication factor Cdt1 [Galeopterus variegatus]
ENSG00000167515(TRAPPC2L)	--	23.4732953	452	22.191296	514	20.00491501	497	26.3702867	586	22.073203	606	38.08701822	699	0.84097642	0.342720108	normal	0.943414634	0.21553831	normal	0.440368517	0.482511375	normal	0.077603223	0.349578569	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Cellular Component: TRAPP complex (GO:0030008);; 	--	--	[S]	Function unknown	"Sedlin, N-terminal conserved region;; Sybindin-like family"	Trafficking protein particle complex subunit 2-like protein GN=TRAPPC2L OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 2-like protein isoform X2 [Galeopterus variegatus]
ENSG00000167522(ANKRD11)	--	26.20187906	4996	30.81940784	5779	27.24408048	5465	28.55225925	4811	31.90292803	5086	35.53033918	6095	0.992252561	-0.085242224	normal	0.985104372	-0.205657551	normal	0.990667574	0.149074204	normal	0.877074375	-0.042689011	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 11 GN=ANKRD11 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 11 isoform X1 [Pteropus alecto] 
ENSG00000167523(SPATA33)	--	5.709076	200	4.807484	166	5.654693	201	4.58538915	165	4.73799724	186	4.7285015	162	0.913583869	-0.305775283	normal	0.958306892	0.141474771	normal	0.90782889	-0.316832531	normal	0.688522978	-0.165354386	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4609)	Spermatogenesis-associated protein 33 GN=SPATA33 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: spermatogenesis-associated protein 33 isoform X1 [Tupaia chinensis] 
ENSG00000167525(PROCA1)	--	1.172298352	45	1.283081529	46	1.163299006	42	1.424412538	54	1.144476751	39	1.14005707	41	0.973732441	0.225176872	normal	0.973685557	-0.250626776	normal	0.980941279	-0.041542854	normal	1	-0.011508168	normal	--	--	Molecular Function: phospholipase A2 activity (GO:0004623);; Biological Process: phospholipid metabolic process (GO:0006644);; Biological Process: arachidonic acid secretion (GO:0050482);; 	--	--	--	--	Phospholipase A2	Protein PROCA1 GN=PROCA1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: protein PROCA1 isoform X2 [Mustela putorius furo] 
ENSG00000167526(RPL13)	--	1409.2353	18975	1262.503081	17176	1281.944441	17718	1427.430651	19440	1491.728898	20108	1370.765063	18445	0.997849487	0.004095742	normal	0.994404237	0.205932169	normal	0.997583287	0.049718425	normal	0.757113651	0.085097045	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02873|2.63628e-129|hsa:6137|RPL13, BBC1, D16S444E, D16S44E, L13; ribosomal protein L13 (EC:3.6.5.3); K02873 large subunit ribosomal protein L13e (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L13e	60S ribosomal protein L13 GN=RPL13 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L13 isoformX1 [Canis lupus familiaris] 
ENSG00000167528(ZNF641)	--	3.183085242	317	3.208519956	290	3.04326665	271	2.968521993	307	4.792133275	441	5.307506458	492	0.965393805	-0.076698665	normal	0.209903131	0.580826447	normal	0.001021756	0.848508989	normal	0.150845492	0.478100218	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:451864|ZNF641; zinc finger protein 641; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; KRAB box"	Zinc finger protein 641 GN=ZNF641 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 641 [Leptonychotes weddellii]
ENSG00000167535(CACNB3)	--	9.512845512	525	7.0388761	373	9.224237085	480	13.19590227	622	13.74369933	681	9.450513697	481	0.944824657	0.213191185	normal	0.000583322	0.844482402	normal	0.971436993	-0.00527236	normal	0.230379445	0.350929168	normal	--	--	Molecular Function: voltage-gated calcium channel activity (GO:0005245);; Cellular Component: voltage-gated calcium channel complex (GO:0005891);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04864|0|hsa:784|CACNB3, CAB3, CACNLB3; calcium channel, voltage-dependent, beta 3 subunit; K04864 voltage-dependent calcium channel beta-3 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Guanylate kinase;; Voltage gated calcium channel subunit beta domain 4Aa N terminal	Voltage-dependent L-type calcium channel subunit beta-3 GN=CACNB3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: voltage-dependent L-type calcium channel subunit beta-3 isoform X1 [Camelus dromedarius]
ENSG00000167543(TP53I13)	--	44.140354	1017	38.03107884	947	38.931932	1022	40.23284015	964	39.43595601	910	43.98046717	1014	0.974673961	-0.107879457	normal	0.975744623	-0.078796062	normal	0.979682444	-0.019599869	normal	0.790293296	-0.069123455	normal	--	--	--	--	--	--	--	--	Tumor protein p53-inducible protein 13 (Precursor) GN=TP53I13 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"PREDICTED: tumor protein p53-inducible protein 13, partial [Tursiops truncatus]"
ENSG00000167548(KMT2D)	--	38.58663545	4786	38.36258359	4963	33.95062157	4923	39.41975711	4571	39.91036634	5337	39.15193797	5497	0.991592187	-0.097110936	normal	0.992356806	0.0833655	normal	0.989773121	0.150771447	normal	0.856106482	0.049738978	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	"K09187|0|hsa:8085|KMT2D, AAD10, ALR, CAGL114, KABUK1, KMS, MLL2, MLL4, TNRC21; lysine (K)-specific methyltransferase 2D (EC:2.1.1.43); K09187 histone-lysine N-methyltransferase MLL2 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[R]	General function prediction only	PHD-finger;; F/Y rich C-terminus;; SET domain;; PHD-like zinc-binding domain;; F/Y-rich N-terminus;; PHD-zinc-finger like domain	Histone-lysine N-methyltransferase 2D GN=KMT2D OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: myeloid/lymphoid or mixed-lineage leukemia 2 [Ceratotherium simum simum]
ENSG00000167549(CORO6)	--	2.978511422	142	3.060495	152	2.914104119	148	2.310798327	115	3.683167	181	2.902524519	119	0.919892245	-0.331099814	normal	0.943457068	0.228407203	normal	0.922698475	-0.319281287	normal	0.827045882	-0.111803123	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K13886|0|nle:100583890|CORO6; coronin 6; K13886 coronin-1B/1C/6 (A)	--	[Z]	Cytoskeleton	"Domain of unknown function (DUF1900);; Domain of unknown function (DUF1899);; WD domain, G-beta repeat"	Coronin-6 GN=CORO6 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: coronin-6 isoform X2 [Camelus ferus] 
ENSG00000167550(RHEBL1)	--	1.781533513	35	2.566447928	51	2.376418924	46	1.029486647	20	0.884848746	17	2.726554353	53	0.916549246	-0.791639651	normal	0.031769659	-1.524414836	normal	0.975022443	0.190236315	normal	0.490571841	-0.570645513	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07849|2.41678e-132|hsa:121268|RHEBL1, RHEBL1c; Ras homolog enriched in brain like 1; K07849 Ras homolog enriched in brain like 1 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	GTPase RhebL1 (Precursor) GN=RHEBL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: GTPase RhebL1 [Orcinus orca] 
ENSG00000167552(TUBA1A)	--	137.8496883	4427	99.96149054	3400	122.405181	4211	230.7512284	7284	174.5192975	5505	161.5695203	5130	0.009189161	0.687381544	normal	0.015276154	0.673543681	normal	0.966757668	0.276414433	normal	0.037198766	0.551735396	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	K07374|0|dpe:Dper_GL12416|GL12416 gene product from transcript GL12416-RA; K07374 tubulin alpha (A)	Phagosome (ko04145)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha-1A chain GN=TUBA1A OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin alpha-1A chain isoform X2 [Orycteropus afer afer]
ENSG00000167553(TUBA1C)	--	506.770465	9600	494.9291291	9000	541.026083	10233	757.682557	14845	642.947117	11981	507.9165292	9746	0.139388246	0.59796101	normal	0.919501013	0.391267708	normal	0.995713493	-0.078626567	normal	0.256782076	0.320729391	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07374|0|nle:100602647|TUBA1C; tubulin, alpha 1c; K07374 tubulin alpha (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha-1C chain GN=TUBA1C OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: tubulin, alpha 1c [Trichechus manatus latirostris]"
ENSG00000167554(ZNF610)	--	0	0	0	0	0	0	0.035756396	1	0.035131757	0	0.02257445	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:162963|ZNF610; zinc finger protein 610; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Transposase zinc-ribbon domain;; C1-like domain"	Zinc finger protein 610 GN=ZNF610 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 160-like isoform X3 [Galeopterus variegatus]
ENSG00000167555(ZNF528)	--	2.011655999	29	1.754526708	33	1.177457801	40	1.62175315	20	0.834998582	25	0.83691233	22	0.972504563	-0.532708331	normal	0.974201962	-0.400795003	normal	0.872198927	-0.827997281	normal	0.356948612	-0.626708899	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:84436|ZNF528; zinc finger protein 528; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger double-stranded RNA-binding;; C1-like domain"	Zinc finger protein 528 GN=ZNF528 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 347-like [Galeopterus variegatus]
ENSG00000167562(ZNF701)	--	0.741454585	39	0.711646185	29	0.503983328	25	0.240722231	12	0.223555954	8	0.197824438	14	0.095214856	-1.610867328	normal	0.259436842	-1.700719134	normal	0.95806551	-0.780900502	normal	0.015918531	-1.473012725	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:55762|ZNF701; zinc finger protein 701; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; BolA-like protein;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 701 GN=ZNF701 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 83-like [Galeopterus variegatus]
ENSG00000167562(ZNF701)-3	--	0.380801341	22	0.358168649	19	0.206644373	12	0.595858094	33	0.461401653	26	0.342699865	24	0.968886625	0.524082557	normal	0.980403805	0.403539908	normal	0.945267363	0.909338618	normal	0.399865595	0.624069932	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000167565(SERTAD3)	--	33.79181838	881	30.16821	777	29.54903	795	23.30288	628	26.65606101	691	21.66375	578	0.277872907	-0.518133735	normal	0.955494178	-0.190262492	normal	0.487342963	-0.467130118	normal	0.026419175	-0.392232197	normal	--	--	--	--	--	--	--	SERTA motif	SERTA domain-containing protein 3 GN=SERTAD3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: SERTA domain-containing protein 3 [Galeopterus variegatus]
ENSG00000167566(NCKAP5L)	--	6.267517	690	5.7059173	664	6.010120377	705	6.871848	782	6.648073	749	6.256389	692	0.964928806	0.149427303	normal	0.963454627	0.152029762	normal	0.974953796	-0.035066736	normal	0.736811006	0.08909741	normal	--	--	--	--	--	--	--	"Nck-associated protein 5, Peripheral clock protein"	Nck-associated protein 5-like GN=NCKAP5L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nck-associated protein 5-like [Galeopterus variegatus] 
ENSG00000167578(RAB4B)	--	26.72325498	522	19.88439371	401	22.433801	458	12.75922766	257	13.83505079	272	18.88552472	369	4.56E-06	-1.048617616	down	0.232357565	-0.578754247	normal	0.874998315	-0.318842928	normal	0.00614961	-0.640994276	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07880|1.5028e-157|ssc:100523381|RAB4B; RAB4B, member RAS oncogene family; K07880 Ras-related protein Rab-4B (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-4B GN=RAB4B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	ras-related protein Rab-4B [Canis lupus familiaris] 
ENSG00000167588(GPD1)	--	0.033402016	2	0.01659577	1	0.067543926	2	0.13658098	8	0.033201455	0	0.033699792	1	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	"Molecular Function: glycerol-3-phosphate dehydrogenase [NAD+] activity (GO:0004367);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: glycerol-3-phosphate catabolic process (GO:0046168);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	K00006|0|ptr:741054|GPD1; glycerol-3-phosphate dehydrogenase 1 (soluble); K00006 glycerol-3-phosphate dehydrogenase (NAD+) [EC:1.1.1.8] (A)	Glycerophospholipid metabolism (ko00564)	[C]	Energy production and conversion	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus;; NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus	"Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic GN=GPD1 OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"PREDICTED: glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic [Galeopterus variegatus]"
ENSG00000167595(PROSER3)	--	14.00198215	978	13.46836068	1006	16.75307164	1084	11.99022001	901	13.15520476	904	16.76355626	1126	0.968640403	-0.148895816	normal	0.963547795	-0.175383896	normal	0.979980304	0.046486993	normal	0.723241561	-0.086287075	normal	--	--	--	--	--	--	--	--	Proline and serine-rich protein 3 GN=PROSER3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C19orf55 homolog [Camelus ferus]
ENSG00000167600(CYP2S1)	--	27.23574169	1298	33.43523234	1400	28.03594	1355	16.403166	726	14.74592921	756	18.52182931	859	5.94E-05	-0.86768712	normal	2.20E-05	-0.909036806	normal	0.014573267	-0.664913952	normal	1.25E-08	-0.81256029	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07420|0|hsa:29785|CYP2S1; cytochrome P450, family 2, subfamily S, polypeptide 1 (EC:1.14.14.1); K07420 cytochrome P450, family 2, subfamily S, polypeptide 1 [EC:1.14.14.1] (A)"	Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2S1 GN=CYP2S1 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2S1 [Galeopterus variegatus]
ENSG00000167601(AXL)	--	59.1174388	5337	50.14438871	4586	65.93619656	6084	98.3940247	9015	62.43491135	5591	55.05013918	5024	0.003412758	0.725303866	normal	0.972941291	0.26436437	normal	0.967877833	-0.284397212	normal	0.623059952	0.271605076	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05115|0|pps:100982279|AXL; AXL receptor tyrosine kinase; K05115 AXL receptor tyrosine kinase [EC:2.7.10.1] (A)	--	--	--	Protein tyrosine kinase;; Protein kinase domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	Tyrosine-protein kinase receptor UFO (Precursor) GN=AXL OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase receptor UFO [Odobenus rosmarus divergens]
ENSG00000167604(NFKBID)	--	4.01933338	201	3.592199655	160	2.900845153	154	2.174900604	109	1.86778157	102	2.204173692	105	0.010008258	-0.904160258	normal	0.369018787	-0.663011616	normal	0.658542254	-0.554200965	normal	0.019884918	-0.726198222	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14214|0|mcc:711338|NF-kappa-B inhibitor delta-like; K14214 NF-kappa-B inhibitor delta (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	NF-kappa-B inhibitor delta GN=NFKBID OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	CAP-Gly domain-containing linker protein 3 [Pteropus alecto]
ENSG00000167608(TMC4)	--	0.445136367	8	0.332820871	7	0.373924369	6	1.046940343	19	1.574070313	28	0.594536941	14	--	--	--	0.252533137	1.774723489	normal	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 4 GN=TMC4 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane channel-like protein 4 isoform 1 [Odobenus rosmarus divergens]
ENSG00000167614(TTYH1)	--	0.112638645	3	0.072590671	2	0.03171549	0	0.066310048	2	0.032333465	0	0.074013082	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Tweety	Protein tweety homolog 1 GN=TTYH1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: protein tweety homolog 1 isoform X1 [Galeopterus variegatus]
ENSG00000167615(LENG8)	--	66.81202963	5743	73.4330966	6085	64.74933879	5561	45.72165443	3767	54.01831903	4525	64.89809518	5341	0.029685312	-0.639007985	normal	0.723086092	-0.448636213	normal	0.993253734	-0.066507438	normal	0.036445631	-0.37132307	normal	--	--	--	--	--	[K]	Transcription	SAC3/GANP/Nin1/mts3/eIF-3 p25 family	Leukocyte receptor cluster member 8 GN=LENG8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: leukocyte receptor cluster member 8 homolog [Leptonychotes weddellii]
ENSG00000167617(CDC42EP5)	--	0.591804	6	0.284366	3	0.0920352	0	0.0976409	1	0.0945218	0	0.194215	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cdc42 effector;; P21-Rho-binding domain	Cdc42 effector protein 5 GN=CDC42EP5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cdc42 effector protein 5 [Dasypus novemcinctus] 
ENSG00000167619(TMEM145)	--	3.954518041	160	3.447297968	139	2.694903327	113	1.344249439	51	1.078897572	42	1.741081782	71	1.03E-07	-1.65070342	down	2.60E-07	-1.712140429	down	0.57142705	-0.667355245	normal	5.35E-05	-1.34963198	down	--	--	Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Biological Process: response to pheromone (GO:0019236);; 	--	--	[S]	Function unknown	Rhodopsin-like GPCR transmembrane domain	Transmembrane protein 145 GN=TMEM145 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 145 isoform X1 [Sus scrofa]
ENSG00000167625(ZNF526)	--	9.376216048	794	10.088468	867	9.808070958	817	7.980661064	673	9.795783001	823	9.925415179	810	0.920264893	-0.268798996	normal	0.973172044	-0.09639352	normal	0.977056411	-0.020667192	normal	0.59763494	-0.124418806	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 526 GN=ZNF526 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 526 [Galeopterus variegatus]
ENSG00000167632(TRAPPC9)	--	12.63666337	1034	9.514965008	870	9.477959696	874	8.875664698	762	14.6697136	1139	11.04718667	936	0.45773039	-0.470387755	normal	0.810492699	0.366695316	normal	0.975115197	0.090432579	normal	0.986622528	0.009736071	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit"	Trafficking protein particle complex subunit 9 GN=TRAPPC9 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 9 isoform X1 [Ailuropoda melanoleuca]
ENSG00000167635(ZNF146)	--	60.49315	3994	61.61423	4084	61.56712	4006	62.81502517	4206	62.75146	4120	69.85105	4633	0.992011145	0.043765847	normal	0.992056018	-0.008761856	normal	0.982984816	0.201422056	normal	0.739197536	0.079919893	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain;; Zinc ribbon domain;; BED zinc finger;; LIM domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Probable zinc-binding domain"	Zinc finger protein OZF GN=ZNF146 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein OZF [Orycteropus afer afer]
ENSG00000167637(ZNF283)	--	4.721889557	230	4.221828734	255	4.565118878	203	4.075605327	200	3.623288471	209	4.318300999	206	0.939662456	-0.230810955	normal	0.901833239	-0.306409925	normal	0.966935894	0.012778667	normal	0.613702275	-0.183233812	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pon:100432361|ZNF283; zinc finger protein 283; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Putative binding domain;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain;; Probable zinc-binding domain"	Zinc finger protein 283 GN=ZNF283 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: zinc finger protein 283-like isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000167641(PPP1R14A)	--	91.07412	958	70.753121	786	107.933596	1215	76.461796	834	66.894227	705	49.425687	529	0.945287596	-0.230414069	normal	0.958886267	-0.177970835	normal	5.82E-10	-1.20556729	down	0.134264606	-0.538734575	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of phosphorylation (GO:0042325);; 	"K12328|8.70108e-76|ptr:104003371|PPP1R14A; protein phosphatase 1, regulatory (inhibitor) subunit 14A; K12328 protein phosphatase 1 regulatory subunit 14A (A)"	Vascular smooth muscle contraction (ko04270)	--	--	PKC-activated protein phosphatase-1 inhibitor	Protein phosphatase 1 regulatory subunit 14A GN=PPP1R14A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 14A [Ceratotherium simum simum]
ENSG00000167642(SPINT2)	--	841.2172759	12312	803.2613764	11360	923.9961322	12552	1173.01172	13624	943.1592197	12146	848.9671426	10866	0.996020499	0.115239266	normal	0.996168324	0.075082214	normal	0.991110173	-0.216359704	normal	0.989997055	-0.005440036	normal	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Kunitz/Bovine pancreatic trypsin inhibitor domain	Kunitz-type protease inhibitor 2 (Precursor) GN=SPINT2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: kunitz-type protease inhibitor 2 [Felis catus] 
ENSG00000167645(YIF1B)	--	102.1236065	1623	88.65764841	1485	96.84051002	1600	81.53562776	1317	90.05971001	1447	98.70002902	1594	0.879247805	-0.331890374	normal	0.982327893	-0.05876394	normal	0.984665247	-0.013698746	normal	0.526314916	-0.131982167	normal	[S]	Function unknown	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	YIF1;; Yip1 domain	Protein YIF1B GN=YIF1B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein YIF1B isoform X1 [Leptonychotes weddellii]
ENSG00000167646(DNAAF3)	--	6.096460046	267	4.363302002	186	5.528515691	247	2.640303394	101	3.83382914	163	3.121199703	137	3.75E-08	-1.419493891	down	0.946940526	-0.210031467	normal	0.010618425	-0.851524168	normal	0.005012778	-0.823720716	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4471);; Domain of unknown function (DUF4470)	"Dynein assembly factor 3, axonemal GN=DNAAF3 OS=Homo sapiens (Human) PE=1 SV=3"	S	Function unknown	"PREDICTED: dynein assembly factor 3, axonemal [Orcinus orca]"
ENSG00000167653(PSCA)	--	1.70576	18	0.829652	11	1.53967071	19	0.998686	12	0.582734	6	0.341376569	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	u-PAR/Ly-6 domain	Prostate stem cell antigen (Precursor) GN=PSCA OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: prostate stem cell antigen [Felis catus]
ENSG00000167654(ATCAY)	--	0.00850342	1	0.047106344	3	0.016991976	1	0.008704279	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18450|0|hsa:85300|ATCAY, BNIP-H, CLAC; ataxia, cerebellar, Cayman type; K18450 caytaxin (A)"	--	--	--	Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2;; Divergent CRAL/TRIO domain;; CRAL/TRIO domain	Caytaxin GN=ATCAY OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: caytaxin [Sus scrofa]
ENSG00000167656(LY6D)	--	0	0	0	0	0	0	0.184768	2	0.180031	1	0.274326	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06846|7.61447e-39|hsa:8581|LY6D, E48, Ly-6D; lymphocyte antigen 6 complex, locus D; K06846 lymphocyte antigen 6 complex (A)"	--	--	--	u-PAR/Ly-6 domain	Lymphocyte antigen 6D (Precursor) GN=LY6D OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lymphocyte antigen 6D-like [Galeopterus variegatus]
ENSG00000167657(DAPK3)	--	19.72916	787	17.3510802	767	21.9540595	876	33.712484	1402	26.297721	1020	27.411923	991	0.00040946	0.801031807	normal	0.756700967	0.389176708	normal	0.964846167	0.169387655	normal	0.070158149	0.467941907	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K08803|0|ptr:455594|DAPK3; death-associated protein kinase 3 (EC:2.7.11.1); K08803 death-associated protein kinase [EC:2.7.11.1] (A)	Pathways in cancer (ko05200);; Bladder cancer (ko05219)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family	Death-associated protein kinase 3 GN=DAPK3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: death-associated protein kinase 3 [Galeopterus variegatus]
ENSG00000167658(EEF2)	--	616.52284	41210	546.79732	36669	533.12396	36216	596.30594	39942	628.12119	41864	641.45269	43069	0.998717009	-0.075917278	normal	0.997731841	0.169716129	normal	0.99586469	0.241721906	normal	0.710853062	0.109195255	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K03234|0|pps:100993607|EEF2; eukaryotic translation elongation factor 2; K03234 elongation factor 2 (A)	AMPK signaling pathway (ko04152);; Oxytocin signaling pathway (ko04921)	[J]	"Translation, ribosomal structure and biogenesis"	"Elongation factor Tu GTP binding domain;; Elongation factor G, domain IV;; Elongation factor G C-terminus;; Elongation Factor G, domain II;; Elongation factor Tu domain 2;; 50S ribosome-binding GTPase"	Elongation factor 2 GN=EEF2 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	"Chain 4, Structure Of The 80s Mammalian Ribosome Bound To Eef2 (this Entry Contains The Large Ribosomal Subunit Proteins)"
ENSG00000167664(TMIGD2)	--	0.043534555	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16668|1.19081e-176|hsa:126259|TMIGD2, IGPR-1, IGPR1; transmembrane and immunoglobulin domain containing 2; K16668 transmembrane and immunoglobulin domain-containing protein 2 (A)"	--	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain	Transmembrane and immunoglobulin domain-containing protein 2 (Precursor) GN=TMIGD2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: transmembrane and immunoglobulin domain-containing protein 2 isoform X1 [Bubalus bubalis]
ENSG00000167670(CHAF1A)	--	12.344994	966	12.32051136	1021	13.675073	1145	12.9986358	1060	13.283592	1036	11.098487	906	0.97541622	0.102980518	normal	0.979416791	-0.000384855	normal	0.844530695	-0.3455418	normal	0.739291315	-0.082540086	normal	--	--	--	"K10750|0|hsa:10036|CHAF1A, CAF-1, CAF1, CAF1B, CAF1P150, P150; chromatin assembly factor 1, subunit A (p150); K10750 chromatin assembly factor 1 subunit A (A)"	--	[B]	Chromatin structure and dynamics	"CAF1 complex subunit p150, region binding to CAF1-p60 at C-term;; CAF1 complex subunit p150, region binding to PCNA;; Chromatin assembly factor 1 complex p150 subunit, N-terminal;; Chromatin assembly factor 1 subunit A"	Chromatin assembly factor 1 subunit A GN=CHAF1A OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: chromatin assembly factor 1 subunit A [Odobenus rosmarus divergens]
ENSG00000167671(UBXN6)	--	26.11501361	945	23.21765116	864	22.17090276	835	20.75877873	763	26.73645377	976	26.7383017	984	0.849300552	-0.338849027	normal	0.967054935	0.154169271	normal	0.946732616	0.228209541	normal	0.951421275	0.021968353	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K14011|0|pps:100969881|UBXN6; UBX domain protein 6; K14011 UBX domain-containing protein 6 (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	PUB domain;; UBX domain	UBX domain-containing protein 6 GN=UBXN6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: UBX domain-containing protein 6 [Ceratotherium simum simum]
ENSG00000167674(CTB-50L17.10)	--	23.16072665	1367	20.315373	1206	23.03741022	1437	20.0935825	1219	22.6304046	1320	15.1457434	901	0.964275708	-0.195914027	normal	0.977435092	0.108751088	normal	0.009607458	-0.680839202	normal	0.329392599	-0.242886156	normal	--	--	--	--	--	[K]	Transcription	Lens epithelium-derived growth factor (LEDGF);; PWWP domain	Hepatoma-derived growth factor-related protein 2 GN=HDGFRP2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hepatoma-derived growth factor-related protein 2 [Galeopterus variegatus]
ENSG00000167676(PLIN4)	--	0.57893015	86	0.441669711	68	0.680267	105	0.195467516	29	0.235745822	35	0.257825	39	0.000419839	-1.54913682	down	0.377655028	-0.94963573	normal	0.000472985	-1.402666227	down	0.00101159	-1.349963848	down	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	Perilipin family;; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III	Perilipin-4 GN=PLIN4 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: perilipin-4 [Ailuropoda melanoleuca]
ENSG00000167680(SEMA6B)	--	23.87232507	1623	13.96828205	994	17.88576779	1291	14.18413949	985	21.292635	1448	14.943465	1009	0.001411675	-0.750377511	normal	0.274196996	0.520657427	normal	0.815953636	-0.363371518	normal	0.69254529	-0.204031103	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06842|0|hsa:10501|SEMA6B, SEM-SEMA-Y, SEMA-VIB, SEMAN, semaZ; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B; K06842 semaphorin 6 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-6B (Precursor) GN=SEMA6B OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: semaphorin-6B [Chrysochloris asiatica]
ENSG00000167685(ZNF444)	--	29.38155592	792	26.54256553	741	29.20557055	816	22.09286117	617	27.25467052	711	25.76593897	685	0.742891163	-0.390201985	normal	0.972455554	-0.080882006	normal	0.926614256	-0.260229513	normal	0.222832775	-0.243403186	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:55311|ZNF444, EZF-2, EZF2, ZSCAN17; zinc finger protein 444; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein 444 GN=ZNF444 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 444 isoform X2 [Galeopterus variegatus]
ENSG00000167693(NXN)	--	48.98365996	2772	48.49250148	2786	52.10803301	3030	20.5280089	1173	19.17973379	1092	24.532128	1394	2.71E-12	-1.270438736	down	6.22E-14	-1.371414661	down	1.47E-09	-1.127527723	down	2.40E-21	-1.251426018	down	--	--	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K17609|0|ocu:100338429|NXN; nucleoredoxin; K17609 nucleoredoxin [EC:1.8.1.8] (A)	--	[R]	General function prediction only	Thioredoxin-like;; Thioredoxin-like domain;; AhpC/TSA family;; Thioredoxin-like domain;; Thioredoxin;; Thioredoxin-like;; Redoxin	Nucleoredoxin GN=NXN OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nucleoredoxin isoform 1 [Dasypus novemcinctus]
ENSG00000167695(FAM57A)	--	20.79857009	725	24.105293	813	18.0850594	678	31.06859101	1030	24.93157443	860	25.356089	906	0.441378706	0.474910998	normal	0.97552726	0.059547049	normal	0.690559107	0.40914223	normal	0.079724821	0.313512178	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	TLC domain	Protein FAM57A GN=FAM57A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein FAM57A [Ochotona princeps]
ENSG00000167699(GLOD4)	--	49.418982	1546	68.01266858	1882	51.78876597	1569	69.418922	2022	54.28451076	1651	61.0967662	1841	0.851905556	0.356100187	normal	0.966603122	-0.210172598	normal	0.96244963	0.222154962	normal	0.574309661	0.120277464	normal	[E]	Amino acid transport and metabolism	--	--	--	[G]	Carbohydrate transport and metabolism	Glyoxalase-like domain;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	Glyoxalase domain-containing protein 4 GN=GLOD4 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: glyoxalase domain-containing protein 4 [Condylura cristata]
ENSG00000167700(MFSD3)	--	40.8949	809	35.9395	746	35.5414	740	33.529	673	45.456	897	33.1995	661	0.898789482	-0.295748578	normal	0.937470139	0.244054085	normal	0.960127261	-0.170796911	normal	0.848304942	-0.061954029	normal	--	--	Molecular Function: acetyl-CoA transporter activity (GO:0008521);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[P]	Inorganic ion transport and metabolism	Major Facilitator Superfamily	Major facilitator superfamily domain-containing protein 3 GN=MFSD3 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	Major facilitator superfamily domain-containing protein 3 [Myotis brandtii]
ENSG00000167701(GPT)	--	0.269188648	8	0.161234047	5	0.2832524	8	0.19871295	6	0.032577	0	0.264973501	8	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00814|0|hsa:2875|GPT, AAT1, ALT1, GPT1; glutamic-pyruvate transaminase (alanine aminotransferase) (EC:2.6.1.2); K00814 alanine transaminase [EC:2.6.1.2] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Aminotransferase class I and II	Alanine aminotransferase 1 GN=GPT OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: alanine aminotransferase 1 [Orcinus orca]
ENSG00000167702(KIFC2)	--	13.18759654	857	11.1423611	735	12.74353611	864	10.4568626	679	11.62904965	757	11.231333	739	0.798781503	-0.365976809	normal	0.975408808	0.021079756	normal	0.942082148	-0.233306358	normal	0.350283491	-0.196013997	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10406|0|hsa:90990|KIFC2; kinesin family member C2; K10406 kinesin family member C2/C3 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIFC2 GN=KIFC2 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	"PREDICTED: kinesin-like protein KIFC2, partial [Galeopterus variegatus]"
ENSG00000167703(SLC43A2)	--	4.68302415	287	4.273187231	325	3.203045514	251	5.883363607	367	5.774599284	384	4.033464683	289	0.877301476	0.322367797	normal	0.939142147	0.218304644	normal	0.947886958	0.194000559	normal	0.368965262	0.246989431	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08229|0|hsa:124935|SLC43A2, LAT4; solute carrier family 43 (amino acid system L transporter), member 2; K08229 MFS transporter, LAT3 family, solute carrier family 43, member 2 (A)"	--	--	--	Major Facilitator Superfamily	Large neutral amino acids transporter small subunit 4 GN=SLC43A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: large neutral amino acids transporter small subunit 4 isoform X1 [Tupaia chinensis] 
ENSG00000167705(RILP)	--	7.169537	191	6.261125898	173	5.218776218	155	7.097579627	178	6.3907302	165	6.674776889	187	0.960502243	-0.131432123	normal	0.963314887	-0.0889364	normal	0.935239056	0.26016451	normal	0.993071467	0.008922164	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K13883|0|hsa:83547|RILP; Rab interacting lysosomal protein; K13883 Rab-interacting lysosomal protein (A)	Phagosome (ko04145);; Salmonella infection (ko05132)	--	--	Rab interacting lysosomal protein;; JNK_SAPK-associated protein-1	Rab-interacting lysosomal protein GN=RILP OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: rab-interacting lysosomal protein [Eptesicus fuscus]
ENSG00000167711(SERPINF2)	--	0.84409872	30	0.820242959	30	0.912731443	32	1.636819634	58	1.682924868	61	1.508739065	53	0.647797091	0.887069058	normal	0.459793668	0.967572057	normal	0.871585458	0.693901934	normal	0.086070582	0.881416206	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K03983|0|hsa:5345|SERPINF2, A2AP, AAP, ALPHA-2-PI, API, PLI; serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2; K03983 alpha-2-antiplasmin (A)"	Complement and coagulation cascades (ko04610)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Alpha-2-antiplasmin (Precursor) GN=SERPINF2 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: alpha-2-antiplasmin isoformX1 [Equus caballus] 
ENSG00000167716(WDR81)	--	10.32486268	1377	15.48741085	1946	15.0000593	1666	11.10025026	1514	11.47427665	1520	18.83662623	2426	0.979780636	0.10589168	normal	0.81550335	-0.377534036	normal	0.215738624	0.533496106	normal	0.86133369	0.110306121	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K17601|0|ptr:468136|WDR81; WD repeat domain 81; K17601 WD repeat-containing protein 81 (A)	--	[S]	Function unknown	"Beige/BEACH domain;; WD domain, G-beta repeat"	WD repeat-containing protein 81 GN=WDR81 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein 81 isoform X1 [Equus caballus]
ENSG00000167720(SRR)	--	16.407158	315	16.752684	254	21.54669	287	9.448435	151	11.186153	202	10.250923	194	2.96E-05	-1.083819627	down	0.868702212	-0.349560308	normal	0.35279507	-0.569611125	normal	0.006020825	-0.666393089	normal	[E]	Amino acid transport and metabolism	--	"K12235|0|hsa:63826|SRR, ILV1, ISO1; serine racemase (EC:4.3.1.17 5.1.1.18 4.3.1.18); K12235 serine racemase [EC:5.1.1.18] (A)"	"Glycine, serine and threonine metabolism (ko00260)"	[TE]	Signal transduction mechanisms;; Amino acid transport and metabolism	Pyridoxal-phosphate dependent enzyme	Serine racemase GN=SRR OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: serine racemase [Galeopterus variegatus] 
ENSG00000167721(TSR1)	--	32.49072	3248	31.011147	3216	33.37803	3351	35.88027	3522	33.90342	3378	28.602174	2867	0.989639708	0.085971954	normal	0.990165097	0.049452673	normal	0.971606244	-0.233227308	normal	0.920488681	-0.028776994	normal	[S]	Function unknown	Cellular Component: nucleus (GO:0005634);; Biological Process: ribosome biogenesis (GO:0042254);; 	"K14799|0|hsa:55720|TSR1; TSR1, 20S rRNA accumulation, homolog (S. cerevisiae); K14799 pre-rRNA-processing protein TSR1 (A)"	--	[S]	Function unknown	Protein of unknown function (DUF663);; AARP2CN (NUC121) domain	Pre-rRNA-processing protein TSR1 homolog GN=TSR1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pre-rRNA-processing protein TSR1 homolog isoform X2 [Lipotes vexillifer]
ENSG00000167740(CYB5D2)	--	15.97266086	501	16.89369	529	13.175783	428	11.75067	373	12.79453	393	19.59159	594	0.581146142	-0.454843975	normal	0.606443888	-0.448670881	normal	0.533029568	0.463165553	normal	0.80267802	-0.12051151	normal	--	--	--	--	--	[R]	General function prediction only	Cytochrome b5-like Heme/Steroid binding domain	Neuferricin (Precursor) GN=CYB5D2 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: neuferricin [Galeopterus variegatus]
ENSG00000167741(GGT6)	--	0	0	0.024309116	1	0.047721715	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: glutathione catabolic process (GO:0006751);; Molecular Function: glutathione hydrolase activity (GO:0036374);; 	K00681|0|hsa:124975|GGT6; gamma-glutamyltransferase 6 (EC:2.3.2.2 3.4.19.13); K00681 gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13] (A)	Taurine and hypotaurine metabolism (ko00430);; Cyanoamino acid metabolism (ko00460);; Glutathione metabolism (ko00480)	[E]	Amino acid transport and metabolism	Gamma-glutamyltranspeptidase	Gamma-glutamyltransferase 6 light chain (Precursor) GN=GGT6 OS=Homo sapiens (Human) PE=2 SV=2	E	Amino acid transport and metabolism	PREDICTED: gamma-glutamyltransferase 6 [Ceratotherium simum simum]
ENSG00000167747(C19orf48)	--	94.7360155	2508	85.118751	2262	96.24543097	2652	96.948736	2527	102.92366	2713	91.03030965	2354	0.988789019	-0.019931783	normal	0.964961706	0.240716444	normal	0.978704389	-0.180148789	normal	0.972552315	0.011926198	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C19orf48 GN=C19orf48 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000167748(KLK1)	--	0	0	0.0819265	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01325|0|hsa:3816|KLK1, KLKR, Klk6, hK1; kallikrein 1 (EC:3.4.21.35); K01325 tissue kallikrein [EC:3.4.21.35] (A)"	Endocrine and other factor-regulated calcium reabsorption (ko04961)	[E]	Amino acid transport and metabolism	Trypsin	Kallikrein-1 (Precursor) GN=KLK1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: kallikrein-1 [Galeopterus variegatus]
ENSG00000167751(KLK2)	--	0.07264806	4	0.017769378	1	0	0	0.018072868	1	0.050309815	1	0.016645719	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	K01325|6.75418e-168|mcf:102139474|KLK2; kallikrein-related peptidase 2; K01325 tissue kallikrein [EC:3.4.21.35] (A)	Endocrine and other factor-regulated calcium reabsorption (ko04961)	[E]	Amino acid transport and metabolism	Trypsin	Kallikrein-2 (Precursor) GN=KLK2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: kallikrein-1-like [Ailuropoda melanoleuca]
ENSG00000167755(KLK6)	--	0.07823536	1	0.122051326	3	0.072407951	1	0	0	0.036301492	0	0.0305837	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K08667|1.2404e-169|pps:103782657|KLK6; kallikrein-related peptidase 6; K08667 kallikrein 6 (neurosin, zyme) [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Kallikrein-6 (Precursor) GN=KLK6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: kallikrein-6 isoform 1 [Ceratotherium simum simum]
ENSG00000167766(ZNF83)	--	1.37933566	55	0.743376479	44	0.845550749	46	0.1887496	10	0.311715021	15	0.243207289	12	3.04E-05	-2.321340584	down	0.099114657	-1.482805662	normal	0.008697776	-1.821724223	down	0.000133145	-1.991065359	down	[R]	General function prediction only	--	"K09228|0|hsa:55769|ZNF83, HPF1, ZNF816B; zinc finger protein 83; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Transposase zinc-ribbon domain;; Prokaryotic RING finger family 1;; BED zinc finger;; Zinc finger, ZZ type;; C1-like domain;; Desulfoferrodoxin, N-terminal domain"	Zinc finger protein 83 GN=ZNF83 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 83-like [Galeopterus variegatus]
ENSG00000167767(KRT80)	--	23.57853	1829	20.35582	1594	25.95301	2034	68.01006	5251	62.64092	4814	41.22525	3201	0	1.489932937	up	0	1.572256524	up	0.020911201	0.645525771	normal	0.000206619	1.259362392	up	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|pps:100974979|KRT80; keratin 80; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 80 GN=KRT80 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: keratin, type II cytoskeletal 80 isoform X1 [Tupaia chinensis]"
ENSG00000167770(OTUB1)	--	734.8456391	4189	752.748332	4215	746.468448	4278	699.0406632	4247	664.3822767	3944	722.0770031	4046	0.992473025	-0.010990036	normal	0.989527643	-0.117256135	normal	0.99105183	-0.088699358	normal	0.766323261	-0.07286134	normal	--	--	--	"K09602|1.85292e-157|rno:293705|Otub1; OTU deubiquitinase, ubiquitin aldehyde binding 1 (EC:3.4.19.12); K09602 ubiquitin thioesterase protein OTUB1 [EC:3.4.19.12] (A)"	--	[S]	Function unknown	Peptidase C65 Otubain;; OTU-like cysteine protease	Ubiquitin thioesterase OTUB1 GN=OTUB1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ubiquitin thioesterase OTUB1 [Ceratotherium simum simum]
ENSG00000167771(RCOR2)	--	3.25425	163	1.55829	79	1.520278	78	1.085648	54	1.533868	77	0.554964	28	2.23E-07	-1.597161719	down	0.971613689	-0.057309496	normal	0.003455924	-1.437862212	down	0.225070071	-1.031947098	normal	--	--	--	--	--	[K]	Transcription	Myb-like DNA-binding domain;; ELM2 domain	REST corepressor 2 GN=RCOR2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: REST corepressor 2 [Tupaia chinensis]
ENSG00000167772(ANGPTL4)	--	65.6953777	2266	40.16858409	1425	51.70450337	1872	50.5276128	1786	36.90661553	1235	12.72738992	452	0.82522356	-0.373961644	normal	0.955207039	-0.227617695	normal	0	-2.054806164	down	0.279250763	-0.704219744	normal	--	--	--	K08767|0|pps:100970952|ANGPTL4; angiopoietin-like 4; K08767 angiopoietin-like 4 (A)	PPAR signaling pathway (ko03320)	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-related protein 4 (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: angiopoietin-related protein 4 [Oryctolagus cuniculus]
ENSG00000167775(CD320)	--	45.374913	965	47.768857	1031	42.665921	933	41.922683	897	35.71250485	754	39.54069	846	0.970471897	-0.136028505	normal	0.472955965	-0.472021248	normal	0.967873324	-0.149256684	normal	0.177729146	-0.251787773	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K06734|3.56295e-141|pps:100972224|CD320; CD320 molecule; K06734 CD320 antigen (A)	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A	CD320 antigen (Precursor) GN=CD320 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CD320 antigen [Galeopterus variegatus]
ENSG00000167778(SPRYD3)	--	13.96998499	772	11.4357	655	13.3999	761	15.9011	886	13.9831	765	15.810813	877	0.963189027	0.167562132	normal	0.951459044	0.202106161	normal	0.95606618	0.196025795	normal	0.376445801	0.187247943	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SPRY domain	SPRY domain-containing protein 3 GN=SPRYD3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: SPRY domain-containing protein 3 isoform X1 [Ursus maritimus]
ENSG00000167779(IGFBP6)	--	64.995375	1326	42.85437	912	63.169325	1354	77.440285	1610	75.051634	1521	65.860453	1363	0.948438959	0.248885617	normal	0.004982214	0.715559649	normal	0.983034182	0.001264973	normal	0.213908596	0.301959649	normal	--	--	--	--	--	--	--	Thyroglobulin type-1 repeat;; Insulin-like growth factor binding protein	Insulin-like growth factor-binding protein 6 (Precursor) GN=IGFBP6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: insulin-like growth factor-binding protein 6 isoform X2 [Lipotes vexillifer]
ENSG00000167780(SOAT2)	--	0.123927608	4	0.060153623	2	0.088048277	2	0.060280942	2	0.030180546	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	--	"K00637|0|hsa:8435|SOAT2, ACACT2, ACAT2, ARGP2; sterol O-acyltransferase 2 (EC:2.3.1.26); K00637 sterol O-acyltransferase [EC:2.3.1.26] (A)"	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	"MBOAT, membrane-bound O-acyltransferase family"	Sterol O-acyltransferase 2 GN=SOAT2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: sterol O-acyltransferase 2 isoform X2 [Physeter catodon]
ENSG00000167785(ZNF558)	--	4.648036214	375	3.421167656	289	5.214061087	372	2.819892733	213	2.701980953	223	3.129347313	263	0.002635058	-0.842225617	normal	0.806159371	-0.393103404	normal	0.47400862	-0.506071915	normal	0.008840203	-0.587961111	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:148156|ZNF558; zinc finger protein 558; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 558 GN=ZNF558 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 558 [Galeopterus variegatus] 
ENSG00000167792(NDUFV1)	--	68.12732239	1849	60.19214927	1732	69.19767117	1941	75.89040899	2154	74.99962616	2083	72.81660218	2031	0.973597252	0.189294927	normal	0.957377188	0.244602374	normal	0.985955296	0.05705522	normal	0.404658547	0.161607244	normal	[C]	Energy production and conversion	"Molecular Function: 4 iron, 4 sulfur cluster binding (GO:0051539);; "	"K03942|0|ptr:747209|NDUFV1; NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa (EC:1.6.5.3 1.6.99.3); K03942 NADH dehydrogenase (ubiquinone) flavoprotein 1 [EC:1.6.5.3 1.6.99.3] (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Respiratory-chain NADH dehydrogenase 51 Kd subunit;; NADH-ubiquinone oxidoreductase-F iron-sulfur binding region;; SLBB domain	"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial (Precursor) GN=NDUFV1 OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial isoform X1 [Elephantulus edwardii]"
ENSG00000167797(CDK2AP2)	--	39.539553	725	30.326626	590	37.294256	696	46.791727	880	52.631634	968	44.932068	807	0.934484369	0.24821224	normal	0.012520805	0.691468585	normal	0.951925152	0.204776368	normal	0.029759275	0.379577238	normal	--	--	--	--	--	[TD]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning"	Cyclin-dependent kinase 2-associated protein	Cyclin-dependent kinase 2-associated protein 2 GN=CDK2AP2 OS=Homo sapiens (Human) PE=1 SV=1	DT	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	PREDICTED: cyclin-dependent kinase 2-associated protein 2 isoform 1 [Canis lupus familiaris] 
ENSG00000167799(NUDT8)	--	15.84349	148	10.95475	108	13.96811	138	13.02265	124	11.25854	104	7.77843	74	0.935403874	-0.282876014	normal	0.967626817	-0.074806801	normal	0.058669167	-0.893772335	normal	0.312281383	-0.406125144	normal	[LR]	"Replication, recombination and repair;; General function prediction only"	Molecular Function: hydrolase activity (GO:0016787);; 	K18665|8.62688e-154|ptr:466894|NUDT8; nudix (nucleoside diphosphate linked moiety X)-type motif 8; K18665 nudix motif 8 [EC:3.6.1.-] (A)	--	--	--	NUDIX domain	"Nucleoside diphosphate-linked moiety X motif 8, mitochondrial (Precursor) GN=NUDT8 OS=Homo sapiens (Human) PE=2 SV=2"	L	"Replication, recombination and repair"	"PREDICTED: LOW QUALITY PROTEIN: nucleoside diphosphate-linked moiety X motif 8, mitochondrial [Eptesicus fuscus]"
ENSG00000167800(TBX10)	--	0.0343779	1	0.0347355	1	0.100906	2	0.0345589	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10181|0|hsa:347853|TBX10, TBX13, TBX7; T-box 10; K10181 T-box protein 10 (A)"	--	[K]	Transcription	T-box	T-box transcription factor TBX10 GN=TBX10 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: T-box transcription factor TBX10 [Galeopterus variegatus]
ENSG00000167815(PRDX2)	--	0.0715762	1	0	0	0	0	0.276747252	4	0.416530242	5	0.349763289	5	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: antioxidant activity (GO:0016209);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: peroxiredoxin activity (GO:0051920);; Biological Process: oxidation-reduction process (GO:0055114);; 	K03386|7.22159e-144|ptr:468740|PRDX2; peroxiredoxin 2; K03386 peroxiredoxin (alkyl hydroperoxide reductase subunit C) [EC:1.11.1.15] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	AhpC/TSA family;; Redoxin;; C-terminal domain of 1-Cys peroxiredoxin	Peroxiredoxin-2 GN=PRDX2 OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peroxiredoxin-2 [Trichechus manatus latirostris]
ENSG00000167840(ZNF232)	--	3.60682	148	3.161762916	136	4.256821775	183	3.090344017	130	2.901497	123	3.379184501	142	0.951571028	-0.215528313	normal	0.958772856	-0.164451037	normal	0.878346097	-0.370756404	normal	0.520594041	-0.26203753	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:7775|ZNF232, ZSCAN11; zinc finger protein 232; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 232 GN=ZNF232 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 232 [Balaenoptera acutorostrata scammoni]
ENSG00000167842(MIS12)	--	15.799545	672	15.51599825	666	15.113694	662	15.419266	675	14.3969337	607	16.84755425	753	0.974704423	-0.024350445	normal	0.961483271	-0.154883661	normal	0.958782877	0.177147529	normal	0.996289322	0.004100139	normal	--	--	"Biological Process: mitotic cell cycle (GO:0000278);; Cellular Component: chromosome, centromeric region (GO:0000775);; Cellular Component: nucleus (GO:0005634);; Biological Process: cell cycle (GO:0007049);; "	K11543|5.00855e-148|ptr:468170|MIS12; MIS12 kinetochore complex component; K11543 kinetochore-associated protein MIS12 (A)	--	--	--	Mis12 protein	Protein MIS12 homolog OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein MIS12 homolog isoform X1 [Physeter catodon] 
ENSG00000167850(CD300C)	--	0	0	0	0	0	0	0.0333822	1	0.0324538	0	0.0659402	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06719|1.15311e-130|hsa:10871|CD300C, CLM-6, CMRF-35, CMRF-35A, CMRF35, CMRF35-A1, CMRF35A, CMRF35A1, IGSF16, LIR; CD300c molecule; K06719 CD300 antigen (A)"	--	--	--	Immunoglobulin V-set domain	CMRF35-like molecule 6 (Precursor) GN=CD300C OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: CMRF35-like molecule 6 [Galeopterus variegatus]
ENSG00000167858(TEKT1)	--	0	0	0	0	0	0	0.0158828	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K18628|0|hsa:83659|TEKT1; tektin 1; K18628 tektin-1 (A)	--	[Z]	Cytoskeleton	Tektin family	Tektin-1 GN=TEKT1 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: tektin-1 [Ceratotherium simum simum]
ENSG00000167861(HID1)	--	6.08208402	385	4.333068474	270	6.073211695	334	6.169327783	400	8.597073258	508	5.62652242	330	0.969279941	0.024214488	normal	0.000476349	0.886764354	normal	0.968165888	-0.025557102	normal	0.427477257	0.302546946	normal	--	--	--	--	--	[R]	General function prediction only	High-temperature-induced dauer-formation protein;; Dyggve-Melchior-Clausen syndrome protein	Protein HID1 GN=HID1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein HID1 [Ochotona princeps]
ENSG00000167862(MRPL58)	--	34.74612	487	28.43122	399	33.5324	462	40.0217	582	43.50948	609	39.48918	574	0.939163912	0.225613364	normal	0.142632645	0.586814255	normal	0.888061877	0.303972124	normal	0.06653678	0.367764578	normal	--	--	Molecular Function: translation release factor activity (GO:0003747);; Biological Process: translational termination (GO:0006415);; 	"K15033|5.63908e-139|hsa:3396|ICT1, DS-1, DS1, MRP-L58; immature colon carcinoma transcript 1 (EC:3.1.1.29); K15033 peptidyl-tRNA hydrolase ICT1 [EC:3.1.1.29] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	RF-1 domain	"Peptidyl-tRNA hydrolase ICT1, mitochondrial (Precursor) GN=ICT1 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: peptidyl-tRNA hydrolase ICT1, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000167863(ATP5H)	--	288.99853	1995	269.101263	1879	292.24385	2046	284.84522	2094	269.77947	1844	253.14454	1768	0.986682871	0.039011107	normal	0.98520826	-0.048513554	normal	0.965804555	-0.218805167	normal	0.755536218	-0.074737386	normal	--	--	--	"K02138|1.00581e-112|ptr:736468|ATP5H; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d; K02138 F-type H+-transporting ATPase subunit d (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"ATP synthase D chain, mitochondrial (ATP5H)"	"ATP synthase subunit d, mitochondrial GN=ATP5H OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: ATP synthase subunit d, mitochondrial [Felis catus] "
ENSG00000167874(TMEM88)	--	0.310042	3	0.204092	2	0.0977622	0	0.589260808	6	0.496268568	4	0.19929	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 88 GN=TMEM88 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 88 [Tupaia chinensis]
ENSG00000167880(EVPL)	--	7.32050904	1219	8.423709087	1454	8.62253935	1502	6.82711346	1140	6.44323291	1065	7.063257756	1176	0.974988874	-0.12733056	normal	0.483518331	-0.470026666	normal	0.827843506	-0.360876491	normal	0.04726856	-0.325276825	normal	--	--	Cellular Component: cytoskeleton (GO:0005856);; 	"K10383|0|hsa:2125|EVPL, EVPK; envoplakin; K10383 envoplakin (A)"	--	[Z]	Cytoskeleton	Plectin repeat	Envoplakin GN=EVPL OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: envoplakin isoform X2 [Galeopterus variegatus]
ENSG00000167881(SRP68)	--	42.518317	2132	43.65015201	2213	44.973556	2266	47.36571835	2371	47.95959665	2408	46.781734	2310	0.983764688	0.122372313	normal	0.98522889	0.100339638	normal	0.987988657	0.019440698	normal	0.733425894	0.079532603	normal	--	--	"Molecular Function: signal recognition particle binding (GO:0005047);; Cellular Component: signal recognition particle, endoplasmic reticulum targeting (GO:0005786);; Biological Process: SRP-dependent cotranslational protein targeting to membrane (GO:0006614);; Molecular Function: 7S RNA binding (GO:0008312);; Molecular Function: endoplasmic reticulum signal peptide binding (GO:0030942);; "	K03107|0|mcf:102114929|SRP68; signal recognition particle 68kDa; K03107 signal recognition particle subunit SRP68 (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	Signal recognition particle subunit SRP68 GN=SRP68 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle subunit SRP68 [Panthera tigris altaica]
ENSG00000167889(MGAT5B)	--	25.53743	2234	20.95543	1879	22.86844	2035	12.202104	1056	13.49715	1179	15.840989	1361	4.31E-09	-1.11071293	down	0.007863538	-0.693116892	normal	0.074976784	-0.58811504	normal	6.95E-09	-0.794126105	normal	--	--	--	"K09661|0|hsa:146664|MGAT5B, GnT-IX, GnT-VB; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B (EC:2.4.1.155); K09661 mannosyl alpha-1,6-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B [EC:2.4.1.-] (A)"	N-Glycan biosynthesis (ko00510);; Other types of O-glycan biosynthesis (ko00514)	--	--	Glycosyltransferase family 18	"Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B GN=MGAT5B OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B [Camelus dromedarius]"
ENSG00000167895(TMC8)	--	0.321238001	24	0.0739215	5	0.116004	7	0.151032	10	0.146109	9	0.163448	11	0.877265313	-1.174209377	normal	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 8 GN=TMC8 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane channel-like protein 8 [Odobenus rosmarus divergens]
ENSG00000167900(TK1)	--	110.41951	2984	126.638069	3201	130.6416356	3600	117.182674	3038	102.419378	2736	88.10978951	2542	0.990259521	-0.004955401	normal	0.966669851	-0.247754246	normal	0.341171581	-0.510067999	normal	0.134357373	-0.256158681	normal	[F]	Nucleotide transport and metabolism	Molecular Function: thymidine kinase activity (GO:0004797);; Molecular Function: ATP binding (GO:0005524);; 	"K00857|7.51432e-165|hsa:7083|TK1, TK2; thymidine kinase 1, soluble (EC:2.7.1.21); K00857 thymidine kinase [EC:2.7.1.21] (A)"	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Thymidine kinase	"Thymidine kinase, cytosolic GN=TK1 OS=Homo sapiens (Human) PE=1 SV=2"	F	Nucleotide transport and metabolism	"PREDICTED: thymidine kinase, cytosolic isoform X1 [Tupaia chinensis] "
ENSG00000167904(TMEM68)	--	16.09847531	430	14.21086875	392	13.72996391	400	13.80154352	387	14.87556901	371	16.10615076	424	0.951277703	-0.182148878	normal	0.963751371	-0.100462565	normal	0.967436227	0.07549556	normal	0.842500772	-0.068984227	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	--	--	[I]	Lipid transport and metabolism	Acyltransferase	Transmembrane protein 68 GN=TMEM68 OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: transmembrane protein 68 [Leptonychotes weddellii]
ENSG00000167920(TMEM99)	--	23.06134072	281	20.53970982	243	23.39089832	273	19.57811051	222	19.65705078	215	40.14570075	478	0.841044795	-0.368569338	normal	0.94689654	-0.196743532	normal	0.003536786	0.796441526	normal	0.851622546	0.180454018	normal	--	--	--	--	--	--	--	--	Transmembrane protein 99 (Precursor) GN=TMEM99 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	--
ENSG00000167925(GHDC)	--	14.94823266	692	12.64998164	608	15.31513292	732	11.05011901	502	13.60827313	620	12.92148762	599	0.397997861	-0.492626542	normal	0.973288577	0.006753699	normal	0.896520069	-0.296899821	normal	0.205678291	-0.260018335	normal	--	--	--	--	--	--	--	GH3 auxin-responsive promoter	GH3 domain-containing protein (Precursor) GN=GHDC OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: GH3 domain-containing protein [Ceratotherium simum simum]
ENSG00000167930(FAM234A)	--	48.7137754	1684	40.77849239	1398	40.58864102	1480	43.06266514	1456	42.791638	1547	43.58895066	1649	0.95386821	-0.24047782	normal	0.977991379	0.124554158	normal	0.976544662	0.147559875	normal	0.985612711	0.007346252	normal	--	--	--	"K17258|0|hsa:83986|ITFG3, C16orf9, gs19; integrin alpha FG-GAP repeat containing 3; K17258 integrin alpha FG-GAP repeat containing protein 3 (A)"	--	--	--	FG-GAP repeat	Protein ITFG3 GN=ITFG3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein ITFG3 [Galeopterus variegatus] 
ENSG00000167941(SOST)	--	0.0239765	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular space (GO:0005615);; 	"K16834|1.2439e-119|hsa:50964|SOST, CDD, SOST1, VBCH; sclerostin; K16834 sclerostin (A)"	Wnt signaling pathway (ko04310)	--	--	Sclerostin (SOST);; DAN domain	Sclerostin (Precursor) GN=SOST OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sclerostin [Tupaia chinensis] 
ENSG00000167945(PRR25)	--	0.160287	3	0.10461	2	0	0	0	0	0.0516563	0	0.157088	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Proline-rich protein 25 GN=PRR25 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	--
ENSG00000167962(ZNF598)	--	20.10412252	1326	20.620761	1384	17.381875	1211	21.334051	1405	20.365075	1324	18.36489632	1253	0.982136743	0.052597883	normal	0.980083519	-0.085272103	normal	0.981403892	0.04084596	normal	1	0.000528717	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Zinc finger protein 598 GN=ZNF598 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: zinc finger protein 598 [Camelus dromedarius]
ENSG00000167964(RAB26)	--	15.53922842	457	11.45747778	351	14.29688911	445	6.121939509	182	9.001603808	272	11.96480733	365	1.38E-09	-1.351621234	down	0.79649415	-0.38738926	normal	0.898880538	-0.293098605	normal	0.070713733	-0.632362638	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07913|4.57575e-169|hsa:25837|RAB26, V46133; RAB26, member RAS oncogene family; K07913 Ras-related protein Rab-26 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-26 GN=RAB26 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-26 [Pteropus alecto]
ENSG00000167965(MLST8)	--	24.68681407	801	26.41625655	851	27.2627129	825	20.398479	674	19.92817716	598	32.13473805	1064	0.912715107	-0.279300981	normal	0.262632338	-0.529311833	normal	0.819483594	0.358161085	normal	0.849854262	-0.104396514	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K08266|0|hsa:64223|MLST8, GBL, GbetaL, LST8, POP3, WAT1; MTOR associated protein, LST8 homolog (S. cerevisiae); K08266 G protein beta subunit-like (A)"	mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151)	[R]	General function prediction only	"WD domain, G-beta repeat"	Target of rapamycin complex subunit LST8 GN=MLST8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: target of rapamycin complex subunit LST8 isoform X1 [Mustela putorius furo] 
ENSG00000167967(E4F1)	--	9.373449245	495	8.677242511	516	8.397713773	470	8.404007404	491	9.781264125	543	8.720514315	497	0.970794918	-0.042405605	normal	0.970454173	0.052005989	normal	0.969144604	0.072068128	normal	0.946746066	0.026664167	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Transcription factor E4F1 GN=E4F1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor E4F1 isoform X4 [Bos taurus]
ENSG00000167969(ECI1)	--	42.540856	854	41.17118318	801	40.02408324	825	40.520414	796	38.987117	805	43.8839504	877	0.969303704	-0.132053742	normal	0.976390767	-0.01421325	normal	0.975131843	0.079749477	normal	0.949407055	-0.022059831	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	"K13238|0|ptr:750080|ECI1, DCI; enoyl-CoA delta isomerase 1; K13238 3,2-trans-enoyl-CoA isomerase, mitochondrial [EC:5.3.3.8] (A)"	Fatty acid degradation (ko00071)	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family	"Enoyl-CoA delta isomerase 1, mitochondrial (Precursor) GN=ECI1 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: enoyl-CoA delta isomerase 1, mitochondrial isoform X1 [Eptesicus fuscus]"
ENSG00000167971(CASKIN1)	--	5.12101	580	3.99684	458	4.8373	567	4.09456	462	4.08734	465	4.05668	465	0.816409302	-0.35792725	normal	0.970235352	0.000455069	normal	0.897568776	-0.293543425	normal	0.332467214	-0.22636885	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; SAM domain (Sterile alpha motif);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; Variant SH3 domain	Caskin-1 GN=CASKIN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: caskin-1 [Odobenus rosmarus divergens]
ENSG00000167972(ABCA3)	--	14.174305	1799	9.553728	1256	12.26451798	1621	17.13636	2217	16.611613	2101	17.711279	2288	0.946342297	0.270373014	normal	0.003884468	0.720135765	normal	0.400878588	0.488526064	normal	0.002431389	0.477562232	normal	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05643|0|hsa:21|ABCA3, ABC-C, ABC3, EST111653, LBM180, SMDP3; ATP-binding cassette, sub-family A (ABC1), member 3; K05643 ATP-binding cassette, subfamily A (ABC1), member 3 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC transporter;; ABC-2 family transporter protein;; AAA domain	ATP-binding cassette sub-family A member 3 GN=ABCA3 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family A member 3 [Equus przewalskii] 
ENSG00000167977(KCTD5)	--	18.13721748	756	18.20281001	770	16.52597012	699	21.77801508	911	20.749859	862	16.912873	706	0.940484563	0.237791828	normal	0.967369356	0.141140776	normal	0.975515628	0.006071216	normal	0.565071937	0.133883997	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD5 GN=KCTD5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD5 isoform X3 [Myotis lucifugus]
ENSG00000167978(SRRM2)	--	70.60646023	13767	75.441005	13918	76.10364	14415	55.16729624	10645	63.548178	12326	72.868476	14449	0.910212014	-0.401819365	normal	0.993100261	-0.196651052	normal	0.997229166	-0.004892118	normal	0.371104844	-0.190201759	normal	--	--	--	"K13172|0|hsa:23524|SRRM2, 300-KD, CWF21, Cwc21, SRL300, SRm300; serine/arginine repetitive matrix 2; K13172 serine/arginine repetitive matrix protein 2 (A)"	--	[A]	RNA processing and modification	cwf21 domain	Serine/arginine repetitive matrix protein 2 GN=SRRM2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: serine/arginine repetitive matrix protein 2-like [Equus caballus]
ENSG00000167981(ZNF597)	--	1.002910811	92	1.034867344	95	1.045815096	94	0.778998246	72	0.89736	82	1.091412651	101	0.931524888	-0.377325977	normal	0.957904703	-0.229788837	normal	0.969114461	0.093873953	normal	0.787624713	-0.160238854	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:146434|ZNF597; zinc finger protein 597; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box"	Zinc finger protein 597 GN=ZNF597 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 597 [Galeopterus variegatus]
ENSG00000167984(NLRC3)	--	0.2613908	34	0.120893194	16	0.037131275	4	0.115089148	15	0.20905763	27	0.167285978	22	0.728957512	-1.132382594	normal	0.962004018	0.683283147	normal	0.276112488	2.085804644	normal	0.898714033	0.223251554	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine Rich repeat;; NACHT domain;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat	Protein NLRC3 GN=NLRC3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	Protein NLRC3 [Pteropus alecto]
ENSG00000167986(DDB1)	--	66.31792269	5891	62.82630526	5641	67.34187832	6005	80.3416233	7097	80.38736126	7077	72.80526	6446	0.982691366	0.23780792	normal	0.963445835	0.305687124	normal	0.99334593	0.093925666	normal	0.265049312	0.212272635	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: nucleus (GO:0005634);; 	"K10610|0|ptr:451234|DDB1; damage-specific DNA binding protein 1, 127kDa; K10610 DNA damage-binding protein 1 (A)"	Nucleotide excision repair (ko03420);; Ubiquitin mediated proteolysis (ko04120);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203)	[L]	"Replication, recombination and repair"	Mono-functional DNA-alkylating methyl methanesulfonate N-term;; CPSF A subunit region	DNA damage-binding protein 1 GN=DDB1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA damage-binding protein 1 [Canis lupus familiaris] 
ENSG00000167987(VPS37C)	--	8.888196589	406	7.1491615	383	9.218606	401	7.6487689	405	11.32020498	402	8.75045309	467	0.969285796	-0.034260272	normal	0.967699312	0.048238632	normal	0.943344124	0.210791575	normal	0.819429101	0.077666824	normal	--	--	--	K12185|4.84755e-174|hsa:55048|VPS37C; vacuolar protein sorting 37 homolog C (S. cerevisiae); K12185 ESCRT-I complex subunit VPS37 (A)	Endocytosis (ko04144)	[S]	Function unknown	Modifier of rudimentary (Mod(r)) protein	Vacuolar protein sorting-associated protein 37C GN=VPS37C OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar protein sorting-associated protein 37C [Tupaia chinensis]
ENSG00000167992(VWCE)	--	0.311062	21	0.264640404	17	0.220165602	15	0.24425255	16	0.179912571	11	0.342316856	24	0.985749579	-0.390333875	normal	--	--	--	0.974115679	0.619986251	normal	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type C domain;; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Coagulation Factor Xa inhibitory site	von Willebrand factor C and EGF domain-containing protein (Precursor) GN=VWCE OS=Homo sapiens (Human) PE=2 SV=2	TVW	Signal transduction mechanisms;; Defense mechanisms;; Extracellular structures	PREDICTED: von Willebrand factor C and EGF domain-containing protein [Ceratotherium simum simum]
ENSG00000167994(RAB3IL1)	--	6.282742634	336	6.482306396	347	5.469370891	298	4.071918616	217	3.242405265	172	5.165466964	277	0.097317311	-0.657823017	normal	8.02E-05	-1.027458379	down	0.961883143	-0.113122211	normal	0.012367683	-0.579503109	normal	--	--	--	K16779|0|ptr:466629|RAB3IL1; RAB3A interacting protein (rabin3)-like 1; K16779 Rab-3A-interacting protein (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	GDP/GTP exchange factor Sec2p	Guanine nucleotide exchange factor for Rab-3A GN=RAB3IL1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: guanine nucleotide exchange factor for Rab-3A isoform X2 [Equus przewalskii]
ENSG00000167995(BEST1)	--	1.822067311	159	2.104815523	178	1.07898949	91	0.834062996	67	1.00838406	90	1.828244347	156	0.000120726	-1.258296333	down	0.004867137	-0.993204479	normal	0.174035907	0.759563599	normal	0.533590558	-0.471130734	normal	--	--	--	"K13878|0|hsa:7439|BEST1, ARB, BEST, BMD, RP50, TU15B, VMD2; bestrophin 1; K13878 bestrophin-1 (A)"	--	[R]	General function prediction only	"Bestrophin, RFP-TM, chloride channel"	Bestrophin-1 GN=BEST1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	Bestrophin-1 [Tupaia chinensis]
ENSG00000167996(FTH1)	--	9985.51236	116147	12163.60075	140571	9367.017272	111228	6771.84718	79164	5913.933228	70384	10168.1709	120355	0.550928539	-0.58385832	normal	9.91E-07	-1.019390319	down	0.999401531	0.105483246	normal	0.178749762	-0.467293424	normal	--	--	Biological Process: cellular iron ion homeostasis (GO:0006879);; Molecular Function: ferric iron binding (GO:0008199);; 	"K00522|1.66837e-134|ptr:738986|FTH1; ferritin, heavy polypeptide 1; K00522 ferritin heavy chain [EC:1.16.3.2] (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Ferritin-like domain	"Ferritin heavy chain, N-terminally processed GN=FTH1 OS=Homo sapiens (Human) PE=1 SV=2"	P	Inorganic ion transport and metabolism	Ferritin heavy chain [Tupaia chinensis]
ENSG00000168000(BSCL2)	--	76.91060393	5108	73.57069865	5143	75.374409	5117	79.08854151	5713	79.73827744	5321	86.29411553	5976	0.991204537	0.130620579	normal	0.993336818	0.027652698	normal	0.984087718	0.215531475	normal	0.568635952	0.125360519	normal	--	--	Biological Process: lipid storage (GO:0019915);; 	--	--	[S]	Function unknown	Putative adipose-regulatory protein (Seipin)	Seipin GN=BSCL2 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: seipin isoform X1 [Galeopterus variegatus]
ENSG00000168002(POLR2G)	--	86.483464	952	71.95420393	810	75.30244444	840	96.54591005	1109	92.831137	1019	87.01160645	975	0.961803175	0.189110651	normal	0.892295098	0.30921799	normal	0.954696275	0.206376288	normal	0.21739404	0.232400958	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K03015|1.97788e-112|cge:100754072|Polr2g; polymerase (RNA) II (DNA directed) polypeptide G; K03015 DNA-directed RNA polymerase II subunit RPB7 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	S1 RNA binding domain;; SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397;; RNA polymerase III subunit Rpc25	DNA-directed RNA polymerase II subunit RPB7 GN=POLR2G OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase II subunit RPB7 [Erinaceus europaeus]
ENSG00000168003(SLC3A2)	--	286.7988359	8929	352.8916575	11270	302.453543	9689	354.442929	10884	313.5902989	9761	482.6080932	14785	0.985223708	0.254766326	normal	0.989093083	-0.22878019	normal	0.128746035	0.601346591	normal	0.560847428	0.224976973	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K06519|0|hsa:6520|SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE; solute carrier family 3 (amino acid transporter heavy chain), member 2; K06519 solute carrier family 3, member 2 (A)"	Protein digestion and absorption (ko04974)	[G]	Carbohydrate transport and metabolism	"Alpha amylase, catalytic domain"	4F2 cell-surface antigen heavy chain GN=SLC3A2 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: 4F2 cell-surface antigen heavy chain [Galeopterus variegatus]
ENSG00000168004(HRASLS5)	--	0	0	0	0	0	0	0.018331556	1	0	0	0.03703694	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lecithin retinol acyltransferase	Ca(2+)-independent N-acyltransferase GN=HRASLS5 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: Ca(2+)-independent N-acyltransferase [Ceratotherium simum simum]
ENSG00000168005(C11orf84)	--	19.19540874	762	21.68277971	865	21.33682825	898	21.97819601	937	22.160207	948	18.039496	760	0.924464612	0.266939729	normal	0.972755041	0.110575664	normal	0.935256751	-0.248551912	normal	0.877071809	0.045396403	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf84 GN=C11orf84 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C11orf84 homolog [Odobenus rosmarus divergens]
ENSG00000168010(ATG16L2)	--	3.474794	125	3.3539985	106	3.846898	138	2.3735916	66	2.463936	81	2.973941785	108	0.052038057	-0.936108877	normal	0.90748253	-0.402900181	normal	0.910027475	-0.357488692	normal	0.15098221	-0.552474399	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	"K17890|0|hsa:89849|ATG16L2, ATG16B, WDR80; autophagy related 16-like 2 (S. cerevisiae); K17890 autophagy-related protein 16, animal type (A)"	Regulation of autophagy (ko04140)	[R]	General function prediction only	"WD domain, G-beta repeat;; Autophagy protein 16 (ATG16)"	Autophagy-related protein 16-2 GN=ATG16L2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: autophagy-related protein 16-2 [Physeter catodon]
ENSG00000168014(C2CD3)	--	9.905745184	1035	9.880299107	1016	11.5942915	1277	8.893240081	1061	9.724965483	1094	13.0665037	1280	0.980080249	0.004954361	normal	0.976944416	0.085163603	normal	0.982370549	-0.00490036	normal	0.945420517	0.025430539	normal	--	--	--	"K16751|0|hsa:26005|C2CD3, OFD14; C2 calcium-dependent domain containing 3; K16751 C2 domain-containing protein 3 (A)"	--	--	--	C2 domain	C2 domain-containing protein 3 GN=C2CD3 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: C2 domain-containing protein 3 [Ceratotherium simum simum]
ENSG00000168016(TRANK1)	--	1.38503371	325	2.054436597	273	1.512201164	268	4.184177568	548	3.38322561	666	4.3702059	770	0.013017272	0.720254454	normal	3.31E-09	1.260580391	up	6.10E-14	1.509078028	up	8.71E-07	1.175664753	up	--	--	--	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; UvrD-like helicase C-terminal domain;; UvrD/REP helicase N-terminal domain	TPR and ankyrin repeat-containing protein 1 GN=TRANK1 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: TPR and ankyrin repeat-containing protein 1 [Galeopterus variegatus]
ENSG00000168026(TTC21A)	--	0.353267	31	0.490292	43	0.5159138	44	0.3714821	32	0.468723	41	0.484436	44	0.984638598	0.014275078	normal	0.97926622	-0.087005242	normal	0.980367113	-0.008015934	normal	0.985435375	-0.032230304	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; PPR repeat;; Tetratricopeptide repeat"	Tetratricopeptide repeat protein 21A GN=TTC21A OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: tetratricopeptide repeat protein 21A [Pteropus alecto]
ENSG00000168028(RPSA)	--	1145.151555	19877	1021.9883	18184	1036.316875	18248	1319.208486	23470	1332.99571	23079	1336.104141	23494	0.995057784	0.208870678	normal	0.981797352	0.322460714	normal	0.970079649	0.356236483	normal	0.1434328	0.293629653	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02998|0|ptr:740423|40S ribosomal protein SA; K02998 small subunit ribosomal protein SAe (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S2	40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016} OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein SA isoform X1 [Orycteropus afer afer]
ENSG00000168032(ENTPD3)	--	0.07933735	4	0.06733511	2	0	0	0	0	0.032756199	0	0.078687344	4	--	--	--	--	--	--	--	--	--	--	--	--	[GO]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Molecular Function: hydrolase activity (GO:0016787);; 	"K01510|0|hsa:956|ENTPD3, CD39L3, HB6, NTPDase-3; ectonucleoside triphosphate diphosphohydrolase 3 (EC:3.6.1.5); K01510 apyrase [EC:3.6.1.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Epstein-Barr virus infection (ko05169)	[F]	Nucleotide transport and metabolism	GDA1/CD39 (nucleoside phosphatase) family	Ectonucleoside triphosphate diphosphohydrolase 3 GN=ENTPD3 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: ectonucleoside triphosphate diphosphohydrolase 3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000168036(CTNNB1)	--	88.62728093	5256	95.34668325	5703	87.9252114	5225	103.3455206	6164	109.3483639	6386	91.77214489	5420	0.986535681	0.199015561	normal	0.991210716	0.141729433	normal	0.993463906	0.044557709	normal	0.55243967	0.129405599	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K02105|0|ptr:450183|CTNNB1; catenin (cadherin-associated protein), beta 1, 88kDa; K02105 catenin beta 1 (A)"	Rap1 signaling pathway (ko04015);; Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Leukocyte transendothelial migration (ko04670);; Melanogenesis (ko04916);; Thyroid hormone signaling pathway (ko04919);; Bacterial invasion of epithelial cells (ko05100);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Basal cell carcinoma (ko05217);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT repeat;; Adaptin N terminal region;; Proteasome non-ATPase 26S subunit;; Kinesin-associated protein (KAP)	Catenin beta-1 GN=CTNNB1 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	catenin beta-1 [Sus scrofa] 
ENSG00000168038(ULK4)	--	1.426758542	90	1.664036331	58	0.481748981	38	1.321872877	57	1.733813304	73	1.70486401	83	0.683604738	-0.675179731	normal	0.9568485	0.303353885	normal	0.075423112	1.088801144	normal	0.828970441	0.174575244	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17545|0|hsa:54986|ULK4, FAM7C1, REC01035; unc-51 like kinase 4 (EC:2.7.11.1); K17545 serine/threonine-protein kinase ULK4 [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase ULK4 GN=ULK4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase ULK4 [Ceratotherium simum simum]
ENSG00000168040(FADD)	--	30.158	1082	25.5357	943	27.9064	1032	42.4345	1527	44.1668	1574	31.3189	1125	0.481200607	0.46560835	normal	0.004741276	0.716780413	normal	0.975072793	0.116027698	normal	0.04581543	0.445269958	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K02373|1.61932e-97|hsa:8772|FADD, MORT1; Fas (TNFRSF6)-associated via death domain; K02373 FAS-associated death domain protein (A)"	Apoptosis (ko04210);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; TNF signaling pathway (ko04668);; Alzheimer's disease (ko05010);; Chagas disease (American trypanosomiasis) (ko05142);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200)	--	--	Death domain;; Death effector domain	FAS-associated death domain protein GN=FADD OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: FAS-associated death domain protein [Galeopterus variegatus]
ENSG00000168056(LTBP3)	--	44.57876922	2822	40.70635356	2698	44.44032887	2656	62.59347796	3598	75.8009043	4524	61.99983887	3705	0.929536409	0.319490574	normal	0.003593106	0.723965354	normal	0.530992872	0.47169854	normal	0.000873267	0.511566825	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K08023|0|hsa:4054|LTBP3, LTBP-3, LTBP2, STHAG6, pp6425; latent transforming growth factor beta binding protein 3; K08023 latent transforming growth factor beta binding protein (A)"	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; TB domain;; EGF-like domain;; Coagulation Factor Xa inhibitory site;; EGF domain	Latent-transforming growth factor beta-binding protein 3 (Precursor) GN=LTBP3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: latent-transforming growth factor beta-binding protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000168060(NAALADL1)	--	0	0	0.020996889	1	0.1227523	1	0.12305	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K01301|0|hsa:10004|NAALADL1, I100, NAALADASEL; N-acetylated alpha-linked acidic dipeptidase-like 1 (EC:3.4.17.21); K01301 N-acetylated-alpha-linked acidic dipeptidase [EC:3.4.17.21] (A)"	--	[OPR]	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism;; General function prediction only"	Transferrin receptor-like dimerisation domain;; Peptidase family M28;; PA domain	N-acetylated-alpha-linked acidic dipeptidase-like protein GN=NAALADL1 OS=Homo sapiens (Human) PE=2 SV=2	OP	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism"	PREDICTED: N-acetylated-alpha-linked acidic dipeptidase-like protein [Galeopterus variegatus]
ENSG00000168061(SAC3D1)	--	32.46147383	660	30.63795	651	32.9832404	716	31.02799514	641	30.57954712	621	26.14029792	532	0.97223057	-0.072801946	normal	0.970138669	-0.089278458	normal	0.611263147	-0.435752992	normal	0.375239879	-0.197716046	normal	--	--	--	"K16734|1.16174e-170|hsa:29901|SAC3D1, HSU79266, SHD1; SAC3 domain containing 1; K16734 SAC3 domain-containing protein 1 (A)"	--	[UD]	"Intracellular trafficking, secretion, and vesicular transport;; Cell cycle control, cell division, chromosome partitioning"	SAC3/GANP/Nin1/mts3/eIF-3 p25 family	SAC3 domain-containing protein 1 GN=SAC3D1 OS=Homo sapiens (Human) PE=1 SV=2	DU	"Cell cycle control, cell division, chromosome partitioning;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: SAC3 domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000168062(BATF2)	--	0.764225914	25	0.360408667	12	0.407099789	16	0.617567475	25	0.7207046	29	0.907736051	39	0.987038705	-0.029047123	normal	0.806833973	1.155422078	normal	0.538029495	1.202213308	normal	0.239088943	0.791286125	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09034|5.23417e-151|pps:100969837|BATF2; basic leucine zipper transcription factor, ATF-like 2; K09034 ATF-like basic leucine zipper transcriptional factor (A)"	--	--	--	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Basic leucine zipper transcriptional factor ATF-like 2 GN=BATF2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	basic leucine zipper transcriptional factor ATF-like 2 [Bos taurus] 
ENSG00000168065(SLC22A11)	--	0.080803842	4	0	0	0.089230932	5	0.08109623	3	0.230188013	7	0.157560188	5	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08207|0|hsa:55867|SLC22A11, OAT4, hOAT4; solute carrier family 22 (organic anion/urate transporter), member 11; K08207 MFS transporter, OCT family, solute carrier family 22 (organic anion/cation transporter), member 11 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 11 GN=SLC22A11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: solute carrier family 22 member 11-like [Ursus maritimus]
ENSG00000168066(SF1)	--	77.84956972	4652	80.48149424	4613	71.16866702	4309	78.71851903	4571	87.76650411	5434	69.6693777	4350	0.992531231	-0.056154831	normal	0.982922185	0.214817771	normal	0.992615356	0.005368985	normal	0.818494955	0.059356839	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: zinc ion binding (GO:0008270);; 	K13095|0|nle:100604364|SF1; splicing factor 1; K13095 splicing factor 1 (A)	--	[A]	RNA processing and modification	KH domain;; KH domain;; Zinc knuckle	Splicing factor 1 GN=SF1 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: splicing factor 1 isoform X1 [Bos taurus]
ENSG00000168067(MAP4K2)	--	6.106980535	495	5.473429028	412	5.537218807	427	4.141568824	326	5.939683	431	4.249363503	338	0.078222165	-0.630956365	normal	0.968525059	0.043461	normal	0.847481058	-0.344131129	normal	0.187193416	-0.305844411	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04414|0|hsa:5871|MAP4K2, BL44, GCK, RAB8IP; mitogen-activated protein kinase kinase kinase kinase 2 (EC:2.7.11.1); K04414 mitogen-activated protein kinase kinase kinase kinase 2 [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010)	[T]	Signal transduction mechanisms	CNH domain;; Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase kinase 2 GN=MAP4K2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	mitogen-activated protein kinase kinase kinase kinase 2 (predicted) [Rhinolophus ferrumequinum]
ENSG00000168070(MAJIN)	--	0	0	0.07551856	1	0	0	0.064750706	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	Domain of unknown function (DUF4544)	Uncharacterized protein C11orf85 GN=C11orf85 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C11orf85 homolog isoform 1 [Orcinus orca]
ENSG00000168071(CCDC88B)	--	5.776206241	201	4.088376894	145	4.267427042	184	4.201887968	141	4.130474449	120	3.868543243	155	0.586290711	-0.537399732	normal	0.931665337	-0.291102099	normal	0.937612019	-0.25345641	normal	0.288338783	-0.370207452	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	HOOK protein	Coiled-coil domain-containing protein 88B GN=CCDC88B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 88B [Ceratotherium simum simum]
ENSG00000168077(SCARA3)	--	21.80129	1481	24.42583	1672	22.32628	1503	22.14757	1564	24.29365	1691	18.69519	1248	0.983492049	0.047788364	normal	0.98483533	-0.005120141	normal	0.931390477	-0.276213058	normal	0.798043519	-0.070048601	normal	--	--	--	--	--	--	--	Collagen triple helix repeat (20 copies)	Scavenger receptor class A member 3 GN=SCARA3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: scavenger receptor class A member 3 isoform X2 [Galeopterus variegatus]
ENSG00000168078(PBK)	--	49.80771181	1494	43.44475817	1357	52.7597186	1617	45.72302639	1448	39.12625395	1167	39.42904852	1203	0.981979055	-0.075871546	normal	0.949649385	-0.238755476	normal	0.61594527	-0.434501571	normal	0.156973379	-0.248397561	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08865|0|hsa:55872|PBK, CT84, HEL164, Nori-3, SPK, TOPK; PDZ binding kinase (EC:2.7.12.2); K08865 PDZ-binding kinase [EC:2.7.12.2] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Lymphokine-activated killer T-cell-originated protein kinase GN=PBK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: lymphokine-activated killer T-cell-originated protein kinase isoform X3 [Tupaia chinensis]
ENSG00000168079(SCARA5)	--	1.732621296	114	0.960610707	81	1.411537784	100	0.495692983	41	1.2913872	100	1.866394992	152	8.19E-05	-1.471646411	down	0.949586199	0.277902873	normal	0.590883373	0.588510924	normal	0.98564369	-0.027396636	normal	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Scavenger receptor cysteine-rich domain;; Collagen triple helix repeat (20 copies);; Scavenger receptor cysteine-rich domain	Scavenger receptor class A member 5 GN=SCARA5 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: scavenger receptor class A member 5 [Tupaia chinensis]
ENSG00000168090(COPS6)	--	77.68307507	2002	77.73023715	2057	76.59847515	2049	86.826709	2256	81.36968138	2097	69.76314182	1833	0.981378899	0.141390573	normal	0.986872341	0.006353883	normal	0.976683489	-0.168872788	normal	0.996295611	-0.003480599	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K12179|0|ptr:463587|COPS6; COP9 signalosome subunit 6; K12179 COP9 signalosome complex subunit 6 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Maintenance of mitochondrial structure and function;; JAB1/Mov34/MPN/PAD-1 ubiquitin protease	COP9 signalosome complex subunit 6 GN=COPS6 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: COP9 signalosome complex subunit 6 [Ceratotherium simum simum]
ENSG00000168092(PAFAH1B2)	--	25.93251291	1539	23.38958295	1393	23.77233127	1396	27.70303311	1663	26.27386909	1545	24.16445455	1440	0.98266675	0.080884984	normal	0.977620261	0.127853185	normal	0.983070217	0.03643956	normal	0.728697096	0.081217462	normal	--	--	--	"K16795|4.33947e-169|umr:103662355|PAFAH1B2; platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa); K16795 platelet-activating factor acetylhydrolase IB subunit beta/gamma [EC:3.1.1.47] (A)"	Ether lipid metabolism (ko00565)	[TV]	Signal transduction mechanisms;; Defense mechanisms	GDSL-like Lipase/Acylhydrolase family;; GDSL-like Lipase/Acylhydrolase	Platelet-activating factor acetylhydrolase IB subunit beta GN=PAFAH1B2 OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: platelet-activating factor acetylhydrolase IB subunit beta isoform X1 [Mustela putorius furo]
ENSG00000168096(ANKS3)	--	9.490737333	394	10.68489131	423	12.35372953	510	13.00436478	503	14.96588125	545	9.931431201	403	0.871538428	0.320422391	normal	0.844219328	0.34308887	normal	0.838072768	-0.346849055	normal	0.736194363	0.107554354	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Ankyrin repeat and SAM domain-containing protein 3 GN=ANKS3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SAM domain-containing protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000168101(NUDT16L1)	--	11.26530425	240	11.925248	255	12.79460676	275	16.78399411	364	19.28556234	402	15.76773659	343	0.285414346	0.56710489	normal	0.117509642	0.632261419	normal	0.891316803	0.308961277	normal	0.026823294	0.50521565	normal	--	--	--	K16867|3.29918e-84|mcf:101926597|uncharacterized LOC101926597; K16867 NUDT16-like protein 1 (A)	Proteoglycans in cancer (ko05205)	--	--	--	Protein syndesmos GN=NUDT16L1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	hypothetical protein PANDA_014021 [Ailuropoda melanoleuca]
ENSG00000168118(RAB4A)	--	11.91359	496	12.851181	538	13.070186	537	14.176065	598	13.376171	557	14.115648	590	0.933724511	0.23830008	normal	0.971664446	0.028565683	normal	0.965167643	0.127159673	normal	0.622401689	0.130337118	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07879|1.38665e-161|pps:100986270|RAB4A; RAB4A, member RAS oncogene family; K07879 Ras-related protein Rab-4A (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-4A GN=RAB4A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-4A isoform X1 [Equus caballus]
ENSG00000168124(OR1F1)	--	0.3942512	11	0.492118	13	0.562413559	17	0.46839254	15	0.601949	9	0.468453648	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:4992|OR1F1, OLFMF, OR16-36, OR16-37, OR16-88, OR16-89, OR16-90, OR1F10, OR1F13P, OR1F4, OR1F5, OR1F6, OR1F7, OR1F8, OR1F9, OR3-145, ORL1023; olfactory receptor, family 1, subfamily F, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 1F1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 1F1-like [Equus caballus]
ENSG00000168131(OR2B2)	--	0.0671911	1	0	0	0.13469	1	0	0	0	0	0.0665431	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:81697|OR2B2, OR2B2Q, OR2B9, OR6-1, dJ193B12.4, hs6M1-10; olfactory receptor, family 2, subfamily B, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 2B2 GN=OR2B2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 2B2 [Oryctolagus cuniculus] 
ENSG00000168135(KCNJ4)	--	0.0808838	3	0	0	0.125253	4	0	0	0.156001	5	0.0785798	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04998|0|ptr:470209|KCNJ4; potassium inwardly-rectifying channel, subfamily J, member 4; K04998 potassium inwardly-rectifying channel subfamily J member 4 (A)"	Cholinergic synapse (ko04725);; Oxytocin signaling pathway (ko04921)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	Inward rectifier potassium channel 4 GN=KCNJ4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: inward rectifier potassium channel 4 [Equus przewalskii]
ENSG00000168137(SETD5)	--	19.48881087	2720	21.73243189	2979	19.78858658	2713	17.6930656	2468	19.3799847	2691	22.04469527	3065	0.980503242	-0.170995063	normal	0.981836931	-0.168022497	normal	0.98231056	0.167618629	normal	0.83344726	-0.053248087	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SET domain	SET domain-containing protein 5 GN=SETD5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: SET domain-containing protein 5 isoform X7 [Galeopterus variegatus]
ENSG00000168140(VASN)	--	5.28119	267	4.19708	215	5.14973	270	3.56717	180	4.15625	210	4.8185	246	0.299704201	-0.59547219	normal	0.964650744	-0.054982558	normal	0.958084144	-0.141760362	normal	0.402602316	-0.261695963	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Fibronectin type III domain;; Leucine rich repeat N-terminal domain	Vasorin (Precursor) GN=VASN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vasorin [Tupaia chinensis]
ENSG00000168143(FAM83B)	--	0.016227138	1	0	0	0.014090754	0	0.4795529	38	0.377459535	31	0.278200505	18	1.06E-06	3.941419866	up	4.84E-06	4.416003034	up	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF1669);; PLD-like domain	Protein FAM83B GN=FAM83B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM83B [Leptonychotes weddellii]
ENSG00000168148(HIST3H3)	--	0.251539	1	0.96826	4	0	0	0	0	0.240466	0	0.240166	1	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	"K11253|2.75966e-94|hsa:8290|HIST3H3, H3.4, H3/g, H3FT, H3t; histone cluster 3, H3; K11253 histone H3 (A)"	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1t GN=HIST3H3 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H3.1t-like isoform 1 [Trichechus manatus latirostris]
ENSG00000168152(THAP9)	--	1.223126	67	0.866633	46	0.663723	37	1.19822	70	0.8280028	47	1.028032	58	0.975119798	0.031651465	normal	0.978625514	0.009297937	normal	0.891096214	0.619845445	normal	0.780958347	0.199824368	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: transposase activity (GO:0004803);; Biological Process: transposition, DNA-mediated (GO:0006313);; "	--	--	--	--	THAP domain	DNA transposase THAP9 GN=THAP9 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: DNA transposase THAP9 [Leptonychotes weddellii]
ENSG00000168159(RNF187)	--	56.7031	2449	56.9501	2441	63.1033	2712	59.1027	2525	63.016	2559	61.3006	2576	0.988736507	0.013250164	normal	0.988007332	0.046653065	normal	0.98769958	-0.082468836	normal	0.976887251	-0.009967275	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K15709|8.00623e-117|mcc:694637|RNF187; ring finger protein 187; K15709 E3 ubiquitin-protein ligase RNF187 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF187 GN=RNF187 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF187-like [Myotis lucifugus]
ENSG00000168172(HOOK3)	--	4.565596556	1044	4.730843139	1085	4.912213115	1111	6.304902	1298	5.761732236	1280	5.723308534	1144	0.921336753	0.28296235	normal	0.956371874	0.216743817	normal	0.980578528	0.03389133	normal	0.362871703	0.178613111	normal	--	--	--	K16536|0|ptr:464153|HOOK3; hook microtubule-tethering protein 3; K16536 protein HOOK3 (A)	--	--	--	HOOK protein	Protein Hook homolog 3 GN=HOOK3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein Hook homolog 3 [Leptonychotes weddellii]
ENSG00000168175(MAPK1IP1L)	--	35.8148356	2006	39.04533452	2169	36.357339	1953	41.74432924	2346	41.56614961	2258	37.35184749	2026	0.973906461	0.194910998	normal	0.987129859	0.036563889	normal	0.986315914	0.044616861	normal	0.683826939	0.091847147	normal	--	--	--	--	--	--	--	--	MAPK-interacting and spindle-stabilizing protein-like GN=MAPK1IP1L OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	hypothetical protein D623_10011183 [Myotis brandtii]
ENSG00000168209(DDIT4)	--	197.754	5831	176.407	5402	123.91	3775	92.0458	2750	126.55	3712	223.78	6634	1.47E-09	-1.114705564	down	0.191222657	-0.56253231	normal	0.000243065	0.804864533	normal	0.791508771	-0.215826164	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: negative regulation of signal transduction (GO:0009968);; 	"K08270|1.59356e-127|hsa:54541|DDIT4, Dig2, REDD-1, REDD1; DNA-damage-inducible transcript 4; K08270 DNA-damage-inducible transcript 4 (A)"	mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; MicroRNAs in cancer (ko05206)	--	--	RTP801 C-terminal region	DNA damage-inducible transcript 4 protein GN=DDIT4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: DNA damage-inducible transcript 4 protein [Tupaia chinensis]
ENSG00000168214(RBPJ)	--	11.02545495	771	15.03325018	949	14.22114169	848	11.34182083	853	10.64821909	774	12.36679647	844	0.971250286	0.114765135	normal	0.884490355	-0.314944258	normal	0.977592053	-0.015085741	normal	0.772016823	-0.076881897	normal	--	--	"Molecular Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding (GO:0000978);; Molecular Function: RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity (GO:0000982);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K06053|0|ptr:461152|RBPJ, RBPSUH; recombination signal binding protein for immunoglobulin kappa J region; K06053 recombining binding protein suppressor of hairless (A)"	Notch signaling pathway (ko04330);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	"Beta-trefoil DNA-binding domain;; LAG1, DNA binding;; IPT/TIG domain"	Recombining binding protein suppressor of hairless GN=RBPJ OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: recombining binding protein suppressor of hairless isoform X1 [Ursus maritimus]
ENSG00000168216(LMBRD1)	--	15.41411355	444	13.84104844	397	15.36461843	434	12.21801474	356	13.56146828	391	15.57602905	449	0.839589755	-0.348165968	normal	0.967943338	-0.043231018	normal	0.969918581	0.040589902	normal	0.712858859	-0.112686107	normal	--	--	--	"K14617|0|hsa:55788|LMBRD1, C6orf209, LMBD1, MAHCF, NESI; LMBR1 domain containing 1; K14617 LMBR1 domain-containing protein 1 (A)"	Vitamin digestion and absorption (ko04977)	--	--	LMBR1-like membrane protein	Probable lysosomal cobalamin transporter GN=LMBRD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: probable lysosomal cobalamin transporter [Tupaia chinensis]
ENSG00000168228(ZCCHC4)	--	3.39999192	142	5.20947579	173	3.078570871	126	4.0460889	162	3.8544174	159	3.095891928	131	0.959155225	0.157672634	normal	0.958690878	-0.141877663	normal	0.9681345	0.047294904	normal	0.986272296	0.013344352	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	GRF zinc finger;; Probable N6-adenine methyltransferase	Zinc finger CCHC domain-containing protein 4 GN=ZCCHC4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger CCHC domain-containing protein 4 isoform 1 [Ceratotherium simum simum] 
ENSG00000168234(TTC39C)	--	6.842856427	286	6.335371131	243	6.6122933	234	4.4429299	208	6.216613969	245	5.22653956	221	0.602390827	-0.48718042	normal	0.965997904	-0.009541983	normal	0.963731995	-0.090153971	normal	0.551414142	-0.200053802	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: mitotic sister chromatid cohesion (GO:0007064);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF3808);; Tetratricopeptide repeat;; Cohesin loading factor;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 39C GN=TTC39C OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 39C [Leptonychotes weddellii]
ENSG00000168237(GLYCTK)	--	1.998134021	41	2.288143554	50	2.088494467	49	2.38253455	63	2.71829566	68	2.989832158	80	0.902275917	0.571505883	normal	0.941367273	0.411472437	normal	0.737441179	0.682292759	normal	0.261670904	0.571438945	normal	[G]	Carbohydrate transport and metabolism	--	K15788|0|ptr:460420|GLYCTK; glycerate kinase; K15788 glycerate kinase [EC:2.7.1.31] (A)	"Glycine, serine and threonine metabolism (ko00260);; Glycerolipid metabolism (ko00561);; Glyoxylate and dicarboxylate metabolism (ko00630)"	[G]	Carbohydrate transport and metabolism	Domain of unknown function (DUF4147);; MOFRL family	Glycerate kinase GN=GLYCTK OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: glycerate kinase [Tupaia chinensis]
ENSG00000168243(GNG4)	--	6.120199087	221	4.911865951	167	5.037266927	172	8.167839431	275	7.192776183	246	5.276829684	165	0.91503658	0.28278778	normal	0.532257275	0.533381391	normal	0.965801163	-0.067626847	normal	0.529032004	0.270033024	normal	--	--	--	"K04541|7.44753e-49|ptr:743331|GNG4; guanine nucleotide binding protein (G protein), gamma 4; K04541 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 (Precursor) GN=GNG4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-4 isoform X2 [Felis catus] 
ENSG00000168246(UBTD2)	--	10.2799	563	11.1682	622	9.93814	546	12.886	711	14.9892	819	13.2933	728	0.887449603	0.305140002	normal	0.787085822	0.374726117	normal	0.704842216	0.405769538	normal	0.04965538	0.362224318	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: ubiquitin binding (GO:0043130);; 	--	--	[S]	Function unknown	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like	Ubiquitin domain-containing protein 2 GN=UBTD2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin domain-containing protein 2 isoform X1 [Loxodonta africana] 
ENSG00000168256(NKIRAS2)	--	26.04554177	1027	29.927969	1172	27.61713236	1120	28.209173	1103	30.69258021	1146	28.62581872	1130	0.978315728	0.072060313	normal	0.979791801	-0.053721979	normal	0.980951729	0.004526513	normal	0.990690818	0.004755083	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17197|2.00299e-117|tup:102489940|NKIRAS2; NFKB inhibitor interacting Ras-like 2; K17197 NF-kappa-B inhibitor-interacting Ras-like protein (A)	--	[T]	Signal transduction mechanisms	Ras family;; Miro-like protein	NF-kappa-B inhibitor-interacting Ras-like protein 2 GN=NKIRAS2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	hypothetical protein PANDA_011145 [Ailuropoda melanoleuca]
ENSG00000168259(DNAJC7)	--	44.59929803	1730	42.19838564	1617	48.12442824	1833	52.33791582	2046	53.12516707	2124	45.98977213	1675	0.967635813	0.211029357	normal	0.832625002	0.371733355	normal	0.979253452	-0.138217796	normal	0.439378065	0.152730807	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K09527|0|ptr:454674|DNAJC7; DnaJ (Hsp40) homolog, subfamily C, member 7; K09527 DnaJ homolog subfamily C member 7 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; DnaJ domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	DnaJ homolog subfamily C member 7 GN=DNAJC7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 7 isoform 1 [Orcinus orca]
ENSG00000168263(KCNV2)	--	0.223816	8	0.380304	14	0.184859	6	0.137703	5	0.0811625	2	0.274697	10	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04935|0|hsa:169522|KCNV2, KV11.1, Kv8.2, RCD3B; potassium channel, subfamily V, member 2; K04935 potassium channel subfamily V member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily V member 2 GN=KCNV2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily V member 2 [Vicugna pacos]
ENSG00000168264(IRF2BP2)	--	51.658049	3828	49.19762	3725	45.13420606	3390	61.90842	4641	62.27262	4637	77.918407	5739	0.97391323	0.246922488	normal	0.956942976	0.294417429	normal	0.001278118	0.750962269	normal	0.008933855	0.43583519	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Interferon regulatory factor 2-binding protein zinc finger	Interferon regulatory factor 2-binding protein 2 GN=IRF2BP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: interferon regulatory factor 2-binding protein 2 isoform 1 [Orcinus orca]
ENSG00000168268(NT5DC2)	--	28.36142732	863	33.50345545	1034	33.16830612	998	34.85353714	1037	36.996023	1088	28.97595704	873	0.945003309	0.233771088	normal	0.978792054	0.051941752	normal	0.956927199	-0.201023648	normal	0.923805752	0.028871805	normal	--	--	--	--	--	[F]	Nucleotide transport and metabolism	5' nucleotidase family	5'-nucleotidase domain-containing protein 2 GN=NT5DC2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: 5'-nucleotidase domain-containing protein 2 isoform X1 [Condylura cristata]
ENSG00000168269(FOXI1)	--	0	0	0.0259189	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09401|0|hsa:2299|FOXI1, FKH10, FKHL10, FREAC-6, FREAC6, HFH-3, HFH3; forkhead box I1; K09401 forkhead box protein I (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein I1 GN=FOXI1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: forkhead box protein I1 isoform X1 [Loxodonta africana]
ENSG00000168273(SMIM4)	--	37.75727	82	7.95314	91	9.97708	75	28.84343	71	21.751001	53	14.71937	74	0.963033475	-0.233921818	normal	0.461755372	-0.784017755	normal	0.973862348	-0.027106509	normal	0.513743471	-0.346304202	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0640	Small integral membrane protein 4 GN=SMIM4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein LOC102395778 isoform X1 [Bubalus bubalis]
ENSG00000168275(COA6)	--	46.363171	434	56.751774	548	60.351313	581	56.26341	547	50.801214	469	59.995668	585	0.889496101	0.302059306	normal	0.929523976	-0.245281982	normal	0.973445448	0.001602861	normal	0.976887251	0.013861307	normal	--	--	Molecular Function: cytochrome-c oxidase activity (GO:0004129);; Cellular Component: mitochondrion (GO:0005739);; 	K18179|4.49984e-109|ggo:101133107|uncharacterized protein C1orf31-like; K18179 cytochrome c oxidase assembly factor 6 (A)	--	[C]	Energy production and conversion	Cytochrome oxidase c subunit VIb	Cytochrome c oxidase assembly factor 6 homolog GN=COA6 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	"hypothetical protein M91_12181, partial [Bos mutus]"
ENSG00000168280(KIF5C)	--	2.92328883	411	1.739854566	245	2.316365	305	0.393068253	55	0.571437902	79	0.342527072	48	0	-2.897623699	down	7.65E-10	-1.635538265	down	0	-2.638230742	down	5.53E-08	-2.421929239	down	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10396|0|tup:102483958|KIF5C; kinesin family member 5C; K10396 kinesin family member 5 (A)	Dopaminergic synapse (ko04728)	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin heavy chain isoform 5C GN=KIF5C OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: kinesin heavy chain isoform 5C isoform X1 [Loxodonta africana]
ENSG00000168282(MGAT2)	--	25.84563	1189	27.73114	1272	26.91955	1206	29.84011	1368	27.89292	1250	30.57846	1369	0.969529201	0.171280794	normal	0.981036715	-0.046541315	normal	0.969148573	0.174395717	normal	0.664238334	0.09942657	normal	--	--	"Cellular Component: Golgi stack (GO:0005795);; Molecular Function: alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity (GO:0008455);; Biological Process: oligosaccharide biosynthetic process (GO:0009312);; Cellular Component: integral component of membrane (GO:0016021);; "	"K00736|0|hsa:4247|MGAT2, CDG2A, CDGS2, GLCNACTII, GNT-II, GNT2; mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase (EC:2.4.1.143); K00736 alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase [EC:2.4.1.143] (A)"	N-Glycan biosynthesis (ko00510)	[G]	Carbohydrate transport and metabolism	N-acetylglucosaminyltransferase II (MGAT2)	"Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase GN=MGAT2 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase isoform X1 [Tupaia chinensis] "
ENSG00000168286(THAP11)	--	26.1536	914	24.9606	898	28.0987	1019	23.626	830	28.7318	1008	24.4744	863	0.963580017	-0.169615724	normal	0.969088218	0.145051078	normal	0.938433268	-0.247613225	normal	0.72173641	-0.088583548	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 11 GN=THAP11 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: THAP domain-containing protein 11 [Odobenus rosmarus divergens]
ENSG00000168288(MMADHC)	--	64.58994158	1354	72.91917204	1526	69.90657929	1435	52.581074	1103	57.94156028	1204	47.703392	996	0.879175302	-0.326216218	normal	0.831006575	-0.362940141	normal	0.203728023	-0.534444608	normal	0.008786978	-0.407026605	normal	--	--	Biological Process: cobalamin metabolic process (GO:0009235);; 	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2246)	"Methylmalonic aciduria and homocystinuria type D protein, mitochondrial (Precursor) GN=MMADHC OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: methylmalonic aciduria and homocystinuria type D protein, mitochondrial isoform X1 [Tupaia chinensis]"
ENSG00000168291(PDHB)	--	37.60972959	916	34.83998758	868	38.92623467	954	28.08338074	695	30.93723771	746	28.66175613	697	0.624955621	-0.428339049	normal	0.939327069	-0.239495372	normal	0.504573695	-0.460264836	normal	0.028452026	-0.377869052	normal	[C]	Energy production and conversion	--	K00162|0|ptr:470832|PDHB; pyruvate dehydrogenase (lipoamide) beta (EC:1.2.4.1); K00162 pyruvate dehydrogenase E1 component beta subunit [EC:1.2.4.1] (A)	Glycolysis / Gluconeogenesis (ko00010);; Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; HIF-1 signaling pathway (ko04066);; Central carbon metabolism in cancer (ko05230)	[C]	Energy production and conversion	"Transketolase, pyrimidine binding domain;; Transketolase, C-terminal domain"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (Precursor) GN=PDHB OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: pyruvate dehydrogenase E1 component subunit beta, mitochondrial isoform X1 [Mustela putorius furo] "
ENSG00000168297(PXK)	--	4.441437037	215	3.4984104	167	4.283754332	183	5.159410301	227	4.9549672	194	4.211989418	189	0.966115644	0.047195138	normal	0.950037556	0.193157936	normal	0.966594781	0.037942601	normal	0.845186733	0.088745853	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17543|0|mcf:101926222|uncharacterized LOC101926222; K17543 PX domain-containing protein kinase-like protein (A)	--	--	--	PX domain;; Protein kinase domain;; WH2 motif;; Protein tyrosine kinase	PX domain-containing protein kinase-like protein OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: PX domain-containing protein kinase-like protein isoform X2 [Mustela putorius furo]
ENSG00000168298(HIST1H1E)	--	0.882846	9	0.566506	6	0	0	0.0927782	1	0.469799	4	0.18872	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11275|3.31705e-32|mcf:102123264|histone H1.4-like; K11275 histone H1/5 (A)	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	Histone H1.4 GN=HIST1H1E OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H1.4-like [Sorex araneus]
ENSG00000168300(PCMTD1)	--	11.63632858	600	12.12024866	656	13.12193522	669	12.61117386	697	10.61133874	573	13.05262079	667	0.955353822	0.184924248	normal	0.944490339	-0.216053823	normal	0.974891813	-0.012582406	normal	0.977244487	-0.012349035	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);; SOCS box	Protein-L-isoaspartate O-methyltransferase domain-containing protein 1 GN=PCMTD1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: protein-L-isoaspartate O-methyltransferase domain-containing protein 1 [Oryctolagus cuniculus]
ENSG00000168301(KCTD6)	--	5.446182737	130	5.87965578	150	4.834714382	120	3.505375993	81	3.557349718	88	4.071738	99	0.393309264	-0.702724392	normal	0.154846145	-0.780415779	normal	0.943677134	-0.281907797	normal	0.101038359	-0.598647065	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD6 GN=KCTD6 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	BTB/POZ domain-containing protein KCTD6 [Myotis brandtii]
ENSG00000168303(MPLKIP)	--	17.18054	399	16.37208	386	17.51928	394	22.02013	415	21.98453	465	18.75139	377	0.969539821	0.02579294	normal	0.927887637	0.246323001	normal	0.967173237	-0.071641408	normal	0.83571174	0.071054971	normal	--	--	--	--	--	--	--	M-phase-specific PLK1-interacting protein	M-phase-specific PLK1-interacting protein GN=MPLKIP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: M-phase-specific PLK1-interacting protein [Odobenus rosmarus divergens]
ENSG00000168306(ACOX2)	--	1.647782912	77	0.633019174	30	0.476871254	22	0.278067728	13	0.395529468	18	0.253784583	12	6.12E-08	-2.462587152	down	0.949225361	-0.711613756	normal	0.964545894	-0.806703784	normal	0.233528019	-1.607250447	normal	[I]	Lipid transport and metabolism	"Molecular Function: acyl-CoA oxidase activity (GO:0003997);; Cellular Component: peroxisome (GO:0005777);; Biological Process: fatty acid beta-oxidation (GO:0006635);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K10214|0|hsa:8309|ACOX2, BCOX, BRCACOX, BRCOX, THCCox; acyl-CoA oxidase 2, branched chain (EC:1.17.99.3); K10214 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase [EC:1.17.99.3] (A)"	Primary bile acid biosynthesis (ko00120);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	"Acyl-CoA oxidase;; Acyl-coenzyme A oxidase N-terminal;; Acyl-CoA dehydrogenase, middle domain"	Peroxisomal acyl-coenzyme A oxidase 2 GN=ACOX2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: peroxisomal acyl-coenzyme A oxidase 2 [Galeopterus variegatus]
ENSG00000168310(IRF2)	--	7.06554597	293	7.340475318	309	8.679934285	367	8.857110547	377	6.718295759	284	9.217662316	365	0.86735762	0.331296736	normal	0.957001417	-0.14241516	normal	0.968994583	-0.016108482	normal	0.875330728	0.061399079	normal	--	--	Molecular Function: regulatory region DNA binding (GO:0000975);; 	"K10153|0|hsa:3660|IRF2, IRF-2; interferon regulatory factor 2; K10153 interferon regulatory factor 2 (A)"	--	--	--	Interferon regulatory factor transcription factor	Interferon regulatory factor 2 GN=IRF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: interferon regulatory factor 2 isoform X1 [Equus caballus]
ENSG00000168329(CX3CR1)	--	0.018349277	1	0.018603385	1	0.01846055	0	0	0	0	0	0.036571745	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04192|0|hsa:1524|CX3CR1, CCRL1, CMKBRL1, CMKDR1, GPR13, GPRV28, V28; chemokine (C-X3-C motif) receptor 1; K04192 CX3C chemokine receptor 1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	CX3C chemokine receptor 1 GN=CX3CR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CX3C chemokine receptor 1 [Balaenoptera acutorostrata scammoni]
ENSG00000168348(INSM2)	--	0	0	0	0	0	0	0	0	0	0	0.0646013	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Insulinoma-associated protein 2 GN=INSM2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: insulinoma-associated protein 2 [Orcinus orca]
ENSG00000168350(DEGS2)	--	0.292561	24	0.283773	24	0.219692	18	0.4282688	28	0.378549	31	0.301114	25	0.985378854	0.180835478	normal	0.979185639	0.329499619	normal	0.98118188	0.434544571	normal	0.711768676	0.32600333	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K04712|0|hsa:123099|DEGS2, C14orf66, DES2, FADS8; delta(4)-desaturase, sphingolipid 2; K04712 sphingolipid delta-4 desaturase [EC:1.14.-.-] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[I]	Lipid transport and metabolism	Fatty acid desaturase;; Sphingolipid Delta4-desaturase (DES)	Sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: sphingolipid delta(4)-desaturase/C4-hydroxylase DES2 [Vicugna pacos]
ENSG00000168374(ARF4)	--	76.33361503	1617	81.3198183	1719	86.64936712	1820	93.5702037	2010	97.00449557	2047	87.46254971	1855	0.935585653	0.282802165	normal	0.962088121	0.230329118	normal	0.985997335	0.019173513	normal	0.353875153	0.176143836	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07939|1.00361e-129|ptr:747376|ARF4; ADP-ribosylation factor 4; K07939 ADP-ribosylation factor 4 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Ras family;; Gtr1/RagA G protein conserved region;; Miro-like protein;; 50S ribosome-binding GTPase	ADP-ribosylation factor 4 GN=ARF4 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor 4 [Orycteropus afer afer]
ENSG00000168385(SEPT2)	--	182.127704	9494	197.487997	9814	189.4742789	9453	155.657266	7931	147.1718426	7546	134.4380794	7010	0.975570226	-0.290294045	normal	0.894802278	-0.400485126	normal	0.792435105	-0.439567276	normal	0.026503179	-0.3766222	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K16942|0|mcf:102138146|SEPT2; septin 2; K16942 septin 2 (A)	Bacterial invasion of epithelial cells (ko05100)	[DZU]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	Septin;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain;; AIG1 family	Septin-2 GN=SEPT2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: septin-2 [Mustela putorius furo] 
ENSG00000168386(FILIP1L)	--	0.379617105	24	1.597358	27	0.436587892	29	0.55254274	44	0.803690012	63	0.39535606	24	0.864217402	0.805078714	normal	0.153235415	1.157382998	normal	0.982913349	-0.266038301	normal	0.347247674	0.689452287	normal	--	--	--	--	--	--	--	Cortactin-binding protein-2	Filamin A-interacting protein 1-like GN=FILIP1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: filamin A-interacting protein 1-like isoform 1 [Orcinus orca]
ENSG00000168389(MFSD2A)	--	2.594967617	84	1.134466801	40	1.532703299	54	3.830944426	124	6.226419307	195	4.3975949	144	0.79101537	0.523128253	normal	7.22E-14	2.222055327	up	4.26E-05	1.382126504	up	0.000984206	1.358457294	up	[G]	Carbohydrate transport and metabolism	--	--	--	[G]	Carbohydrate transport and metabolism	MFS/sugar transport protein;; Major Facilitator Superfamily	Sodium-dependent lysophosphatidylcholine symporter 1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: major facilitator superfamily domain-containing protein 2A [Camelus ferus] 
ENSG00000168393(DTYMK)	--	65.01797	1297	68.237203	1399	73.2408	1522	46.100316	959	42.7852	852	54.07764739	1096	0.47558065	-0.465763597	normal	0.003042399	-0.735866819	normal	0.412294128	-0.481445658	normal	0.000155181	-0.557664512	normal	[F]	Nucleotide transport and metabolism	--	K00943|1.80243e-154|pps:100984870|DTYMK; deoxythymidylate kinase (thymidylate kinase); K00943 dTMP kinase [EC:2.7.4.9] (A)	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Thymidylate kinase	Thymidylate kinase GN=DTYMK OS=Homo sapiens (Human) PE=1 SV=4	F	Nucleotide transport and metabolism	PREDICTED: small nuclear ribonucleoprotein-associated protein B' isoform X1 [Mustela putorius furo] 
ENSG00000168394(TAP1)	--	14.27802761	720	13.17109503	680	14.85866606	767	18.90474	932	17.30460918	867	19.76659144	1001	0.845610245	0.340859998	normal	0.865799571	0.328422459	normal	0.782133806	0.375202657	normal	0.046323509	0.348893556	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05653|0|hsa:6890|TAP1, ABC17, ABCB2, APT1, D6S114E, PSF-1, PSF1, RING4, TAP1*0102N, TAP1N; transporter 1, ATP-binding cassette, sub-family B (MDR/TAP); K05653 ATP-binding cassette, subfamily B (MDR/TAP), member 2 (A)"	ABC transporters (ko02010);; Phagosome (ko04145);; Antigen processing and presentation (ko04612);; Herpes simplex infection (ko05168);; Primary immunodeficiency (ko05340)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ABC transporter transmembrane region;; ABC transporter;; AAA ATPase domain;; Predicted ATPase of the ABC class	Antigen peptide transporter 1 GN=TAP1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: antigen peptide transporter 1 [Ceratotherium simum simum]
ENSG00000168395(ING5)	--	11.45908893	684	11.74006668	667	12.15535822	694	6.762781285	419	7.771947877	470	7.643341638	433	0.005778524	-0.735743876	normal	0.303002189	-0.525026671	normal	0.017014315	-0.686947025	normal	0.00016005	-0.65036267	normal	--	--	--	"K11345|3.28123e-145|ptr:460085|ING5; inhibitor of growth family, member 5; K11345 inhibitor of growth protein 5 (A)"	--	[B]	Chromatin structure and dynamics	Inhibitor of growth proteins N-terminal histone-binding	Inhibitor of growth protein 5 GN=ING5 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: inhibitor of growth protein 5 [Odobenus rosmarus divergens] 
ENSG00000168397(ATG4B)	--	21.819787	805	19.913139	863	20.166684	779	11.70690076	478	12.350238	499	15.108041	561	0.001470883	-0.780852723	normal	0.000809249	-0.809856427	normal	0.434931434	-0.480808997	normal	2.07E-05	-0.690804052	normal	--	--	--	"K08342|0|hsa:23192|ATG4B, APG4B, AUTL1; autophagy related 4B, cysteine peptidase; K08342 cysteine protease ATG4 [EC:3.4.22.-] (A)"	Regulation of autophagy (ko04140)	[ZU]	"Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	Peptidase family C54	Cysteine protease ATG4B GN=ATG4B OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cysteine protease ATG4B [Ceratotherium simum simum]
ENSG00000168404(MLKL)	--	7.989278774	331	7.851728495	355	11.17174818	399	13.96731525	546	11.44236602	468	10.42142487	463	0.024628319	0.688724696	normal	0.797756557	0.375864504	normal	0.945039254	0.205607964	normal	0.041985752	0.423501292	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08849|0|ptr:736069|MLKL; mixed lineage kinase domain-like; K08849 mixed lineage kinase domain-like [EC:2.7.11.1] (A)	TNF signaling pathway (ko04668)	--	--	Protein tyrosine kinase;; Protein kinase domain	Mixed lineage kinase domain-like protein OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mixed lineage kinase domain-like protein isoform X1 [Galeopterus variegatus]
ENSG00000168411(RFWD3)	--	22.21059572	2087	21.46006431	2028	23.680548	2180	25.159238	2370	24.32911882	2188	22.415587	2075	0.980748416	0.152518783	normal	0.984940585	0.088065296	normal	0.985783739	-0.07945174	normal	0.831647481	0.053965456	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K15691|0|hsa:55159|RFWD3, RNF201; ring finger and WD repeat domain 3; K15691 E3 ubiquitin-protein ligase RFWD3 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; WD domain, G-beta repeat"	E3 ubiquitin-protein ligase RFWD3 GN=RFWD3 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RFWD3 [Ceratotherium simum simum]
ENSG00000168412(MTNR1A)	--	0.0538345	1	0.417025	8	0.15424	2	0.157899	3	0.0517586	0	0.105603	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04285|0|hsa:4543|MTNR1A, MEL-1A-R, MT1; melatonin receptor 1A; K04285 melatonin receptor type 1A (A)"	Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Melatonin receptor type 1A GN=MTNR1A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: melatonin receptor type 1A [Ceratotherium simum simum]
ENSG00000168418(KCNG4)	--	0.0103037	1	0	0	0.0200867	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04903|0|hsa:93107|KCNG4, KV6.3, KV6.4; potassium voltage-gated channel, subfamily G, member 4; K04903 potassium voltage-gated channel subfamily G member 4 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily G member 4 GN=KCNG4 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily G member 4 [Galeopterus variegatus]
ENSG00000168421(RHOH)	--	0.263788304	3	0	0	0.03004408	0	0.104973987	2	0.104018514	1	0.052591732	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07873|1.49713e-126|hsa:399|RHOH, ARHH, TTF; ras homolog family member H; K07873 Ras homolog gene family, member H (A)"	Leukocyte transendothelial migration (ko04670)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoH (Precursor) GN=RHOH OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoH [Galeopterus variegatus]
ENSG00000168427(KLHL30)	--	0.2069976	12	0.3311484	19	0.18062739	9	0.018820205	1	0.073437447	3	0.260880716	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K10466|0|hsa:377007|KLHL30; kelch-like family member 30; K10466 kelch-like protein 30 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 30 GN=KLHL30 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 30 [Galeopterus variegatus]
ENSG00000168434(COG7)	--	8.051032003	474	8.233064005	484	7.987469	436	5.328075014	312	7.4307	433	6.87274	404	0.082288324	-0.631629622	normal	0.951713885	-0.181466734	normal	0.963468616	-0.117839556	normal	0.189967126	-0.299375263	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Cellular Component: Golgi transport complex (GO:0017119);; 	--	--	[S]	Function unknown	Golgi complex component 7 (COG7)	Conserved oligomeric Golgi complex subunit 7 GN=COG7 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: conserved oligomeric Golgi complex subunit 7 [Tupaia chinensis]
ENSG00000168438(CDC40)	--	6.99916	470	7.3174591	495	7.86692	513	6.96191	471	6.605258958	434	7.37332	491	0.970799781	-0.027675586	normal	0.943237121	-0.210472724	normal	0.969575999	-0.07131234	normal	0.725058255	-0.103350698	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K12816|0|ptr:462936|CDC40; cell division cycle 40; K12816 pre-mRNA-processing factor 17 (A)	Spliceosome (ko03040)	[S]	Function unknown	"WD domain, G-beta repeat"	Pre-mRNA-processing factor 17 GN=CDC40 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pre-mRNA-processing factor 17 [Equus przewalskii]
ENSG00000168439(STIP1)	--	127.5641116	6913	117.5120241	6346	137.331192	7494	132.1281595	7174	126.7718181	6785	96.61741446	5215	0.994970512	0.022628619	normal	0.99385704	0.075057437	normal	0.331323307	-0.531230931	normal	0.582785175	-0.136003103	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K09553|0|hsa:10963|STIP1, HEL-S-94n, HOP, IEF-SSP-3521, P60, STI1, STI1L; stress-induced phosphoprotein 1; K09553 stress-induced-phosphoprotein 1 (A)"	Prion diseases (ko05020)	[O]	"Posttranslational modification, protein turnover, chaperones"	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; NMDA receptor-regulated protein 1;; Tetratricopeptide repeat"	Stress-induced-phosphoprotein 1 GN=STIP1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: stress-induced-phosphoprotein 1 [Camelus ferus]
ENSG00000168447(SCNN1B)	--	0.062875361	3	0.283500476	11	0.100224969	1	0	0	0.040229598	1	0.020676147	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	"K04825|0|mcf:102144896|SCNN1B; sodium channel, non-voltage-gated 1, beta subunit; K04825 amiloride-sensitive sodium channel subunit beta (A)"	Taste transduction (ko04742);; Aldosterone-regulated sodium reabsorption (ko04960)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Amiloride-sensitive sodium channel subunit beta GN=SCNN1B OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: amiloride-sensitive sodium channel subunit beta isoform X1 [Canis lupus familiaris] 
ENSG00000168453(HR)	--	10.15075783	1248	4.625366558	584	7.117772761	909	2.828388082	343	7.415029093	906	1.969837417	241	0	-1.889408934	down	0.070140619	0.610836692	normal	0	-1.916879339	down	0.308194368	-0.900447972	normal	--	--	--	--	--	[K]	Transcription	"JmjC domain, hydroxylase"	Lysine-specific demethylase hairless GN=HR OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: lysine-specific demethylase hairless isoform X1 [Galeopterus variegatus]
ENSG00000168454(TXNDC2)	--	0.156415794	3	0	0	0	0	0.018665798	1	0.019238911	0	0.019528841	1	--	--	--	--	--	--	--	--	--	--	--	--	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; Molecular Function: nutrient reservoir activity (GO:0045735);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; High molecular weight glutenin subunit	Thioredoxin domain-containing protein 2 GN=TXNDC2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin domain-containing protein 2 [Pantholops hodgsonii]
ENSG00000168461(RAB31)	--	15.2916	1040	14.6004	999	11.8335	798	17.0724	1170	17.7677	1204	14.7276	1002	0.972553178	0.138899203	normal	0.942374641	0.247510545	normal	0.877969341	0.319588817	normal	0.246159917	0.228950143	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07891|3.24034e-145|ptr:468476|RAB31; RAB31, member RAS oncogene family; K07891 Ras-related protein Rab-22 (A)"	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-31 GN=RAB31 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-31 isoform X2 [Physeter catodon]
ENSG00000168476(REEP4)	--	48.583027	1289	38.94247899	965	38.1734143	1102	43.75566104	1093	45.0687449	1235	41.21818027	1034	0.932031346	-0.268443154	normal	0.868431753	0.334019904	normal	0.976463309	-0.100037727	normal	0.961362946	-0.018671467	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K17338|0|hsa:80346|REEP4, C8orf20; receptor accessory protein 4; K17338 receptor expression-enhancing protein 1/2/3/4 (A)"	--	[V]	Defense mechanisms	"TB2/DP1, HVA22 family"	Receptor expression-enhancing protein 4 GN=REEP4 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: receptor expression-enhancing protein 4 [Galeopterus variegatus]
ENSG00000168477(TNXB)	--	21.45800891	1233	24.24671071	1263	20.72092347	1178	22.39637237	1163	21.56017462	1137	27.82576625	1445	0.976532047	-0.115006373	normal	0.96796729	-0.172830709	normal	0.922745879	0.286106338	normal	0.986272296	0.006945626	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06252|0|hsa:7148|TNXB, EDS3, HXBL, TENX, TN-X, TNX, TNXB1, TNXB2, TNXBS, VUR8, XB, XBS; tenascin XB; K06252 tenascin (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; MicroRNAs in cancer (ko05206)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Fibronectin type III domain;; Fibrinogen beta and gamma chains, C-terminal globular domain;; EGF-like domain;; Human growth factor-like EGF;; Uncharacterised conserved protein (DUF2369)"	Tenascin-X (Precursor) GN=TNXB OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: tenascin-X [Pteropus alecto]
ENSG00000168481(LGI3)	--	0.882862812	52	0.3044361	18	0.405557139	23	0.616245448	36	1.568274024	85	0.335696194	20	0.933708491	-0.541987828	normal	8.14E-07	2.128113236	up	0.986945332	-0.196088414	normal	0.721687143	0.578308839	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	EPTP domain;; Leucine rich repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeats (2 copies)	Leucine-rich repeat LGI family member 3 (Precursor) GN=LGI3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat LGI family member 3 [Bos mutus]
ENSG00000168484(SFTPC)	--	0	0	0.237584	2	0.090821758	0	0.0619647	1	0.128389624	1	0.277205054	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Surfactant protein C, N terminal propeptide;; BRICHOS domain"	Pulmonary surfactant-associated protein C (Precursor) GN=SFTPC OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: pulmonary surfactant-associated protein C isoform X1 [Sorex araneus]
ENSG00000168487(BMP1)	--	13.611345	1052	15.181129	1097	13.53488	1040	32.07772	2438	37.590694	2844	27.36588612	2131	2.35E-10	1.180566715	up	1.80E-13	1.351731284	up	1.44E-07	1.025591711	up	9.20E-11	1.195434924	up	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: proteolysis (GO:0006508);; 	K05502|0|pon:100453093|BMP1; bone morphogenetic protein 1; K05502 bone morphogenetic protein 1 [EC:3.4.24.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	CUB domain;; Astacin (Peptidase family M12A);; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; EGF-like domain	Bone morphogenetic protein 1 (Precursor) GN=BMP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: bone morphogenetic protein 1 [Ovis aries]
ENSG00000168488(ATXN2L)	--	47.43903	3346	53.38714188	3805	51.52951446	3759	40.77878707	2824	43.16254119	2888	59.73440754	4153	0.956461679	-0.275391767	normal	0.765577504	-0.419060425	normal	0.988462642	0.135461647	normal	0.627811815	-0.165237334	normal	--	--	--	--	--	[A]	RNA processing and modification	Ataxin 2 SM domain;; LsmAD domain;; Ataxin-2 C-terminal region	Ataxin-2-like protein GN=ATXN2L OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ataxin-2-like protein isoform 1 [Orcinus orca] 
ENSG00000168490(PHYHIP)	--	0.256774543	12	0.189529697	9	0.398753135	6	0.608612254	24	0.271807535	12	0.550820931	26	0.951165332	0.887552839	normal	--	--	--	0.258496703	1.865522991	normal	--	--	--	--	--	--	--	--	--	--	--	Phytanoyl-CoA hydroxylase-interacting protein GN=PHYHIP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: phytanoyl-CoA hydroxylase-interacting protein [Trichechus manatus latirostris] 
ENSG00000168491(CCDC110)	--	0.104775228	3	0.018574973	1	0	0	0	0	0	0	0.017914761	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 110 GN=CCDC110 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 110 [Galeopterus variegatus]
ENSG00000168495(POLR3D)	--	11.399842	796	11.60857	834	12.931934	821	11.82645	840	13.79018359	952	12.98673	893	0.976319084	0.046700883	normal	0.963725972	0.169200308	normal	0.972311516	0.112787258	normal	0.645195644	0.110598885	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Cellular Component: DNA-directed RNA polymerase III complex (GO:0005666);; Biological Process: transcription from RNA polymerase III promoter (GO:0006383);; 	"K03026|0|ptr:464043|POLR3D; polymerase (RNA) III (DNA directed) polypeptide D, 44kDa; K03026 DNA-directed RNA polymerase III subunit RPC4 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase III RPC4	DNA-directed RNA polymerase III subunit RPC4 GN=POLR3D OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC4 [Ceratotherium simum simum]
ENSG00000168497(SDPR)	--	18.08	1136	19.0129	1193	21.2539	1331	8.51737	536	5.59402	351	6.81884	430	2.29E-08	-1.112245619	down	0	-1.782043271	down	0	-1.634947496	down	4.98E-25	-1.496426125	down	--	--	--	--	--	--	--	PTRF/SDPR family	Serum deprivation-response protein OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: serum deprivation-response protein [Galeopterus variegatus]
ENSG00000168502(MTCL1)	--	17.51622737	2637	17.97168104	2715	20.17047301	3031	25.03383574	3797	25.2233229	3757	23.36676651	3481	0.419239056	0.494888695	normal	0.665730665	0.446989864	normal	0.98072176	0.191327378	normal	0.015607827	0.375338491	normal	--	--	Cellular Component: extracellular space (GO:0005615);; Biological Process: regulation of autophagy (GO:0010506);; 	--	--	--	--	Protein of unknown function (DUF3166);; Domain of unknown function (DUF4482)	Microtubule cross-linking factor 1 GN=MTCL1 OS=Homo sapiens (Human) PE=1 SV=5	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: microtubule cross-linking factor 1 [Oryctolagus cuniculus]
ENSG00000168505(GBX2)	--	2.372303085	91	1.2026882	45	1.746929418	66	1.103022045	39	1.340639121	51	0.624123464	20	0.011173303	-1.2207935	normal	0.975738046	0.154273437	normal	0.001570588	-1.657896276	down	0.162257761	-0.899238168	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09321|0|nle:100596042|GBX2; gastrulation brain homeobox 2; K09321 homeobox protein GBX (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein GBX-2 GN=GBX2 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: homeobox protein GBX-2 [Canis lupus familiaris]
ENSG00000168517(HEXIM2)	--	10.70679645	281	13.19558647	288	11.4473613	293	10.15371231	212	8.078212612	189	15.78978501	289	0.734741958	-0.43459211	normal	0.20704417	-0.625026081	normal	0.967407037	-0.027977215	normal	0.211287867	-0.341338665	normal	--	--	Biological Process: negative regulation of transcription from RNA polymerase II promoter (GO:0000122);; Molecular Function: cyclin-dependent protein serine/threonine kinase inhibitor activity (GO:0004861);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: snRNA binding (GO:0017069);; 	K15189|0|ptr:454747|HEXIM2; hexamethylene bis-acetamide inducible 2; K15189 protein HEXIM1/2 (A)	--	--	--	Hexamethylene bis-acetamide-inducible protein	Protein HEXIM2 GN=HEXIM2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein HEXIM2 [Galeopterus variegatus]
ENSG00000168522(FNTA)	--	25.73986804	829	25.72314802	843	26.41409631	835	25.64721542	828	22.33271625	709	24.1949784	768	0.976934711	-0.032513303	normal	0.920913408	-0.270643385	normal	0.969474302	-0.128718168	normal	0.534325037	-0.142681763	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein prenyltransferase activity (GO:0008318);; Biological Process: protein prenylation (GO:0018342);; 	"K05955|0|hsa:2339|FNTA, FPTA, PGGT1A, PTAR2; farnesyltransferase, CAAX box, alpha (EC:2.5.1.59 2.5.1.58); K05955 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [EC:2.5.1.58 2.5.1.59] (A)"	Terpenoid backbone biosynthesis (ko00900)	[O]	"Posttranslational modification, protein turnover, chaperones"	Protein prenyltransferase alpha subunit repeat	Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha GN=FNTA OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha [Mustela putorius furo]
ENSG00000168528(SERINC2)	--	13.11290513	410	8.079273	221	12.42361963	384	24.47681201	745	28.12581634	862	27.922683	875	0.000557806	0.828449458	normal	0	1.934996705	up	7.57E-09	1.176729443	up	5.05E-10	1.269829786	up	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Serine incorporator (Serinc)	Serine incorporator 2 GN=SERINC2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: serine incorporator 2 [Orycteropus afer afer]
ENSG00000168538(TRAPPC11)	--	8.832446699	732	7.675963799	635	8.203384251	658	8.218580799	656	7.465717731	615	9.085132859	725	0.955374588	-0.18856173	normal	0.971520974	-0.067433541	normal	0.967116312	0.131314353	normal	0.895442474	-0.041771822	normal	--	--	--	--	--	[S]	Function unknown	"Gryzun, putative trafficking through Golgi;; Foie gras liver health family 1;; Gryzun, putative Golgi trafficking"	Trafficking protein particle complex subunit 11 GN=TRAPPC11 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 11 isoform X1 [Tupaia chinensis] 
ENSG00000168542(COL3A1)	--	0.00813096	1	0.015729901	2	0.023596766	2	0.123332608	14	0.097245844	10	0.065736755	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Molecular Function: protein binding (GO:0005515);; 	"K06236|1.38814e-152|ptr:459815|COL3A1; collagen, type III, alpha 1; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; von Willebrand factor type C domain	Collagen alpha-1(III) chain (Precursor) GN=COL3A1 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	"PREDICTED: collagen alpha-1(III) chain-like, partial [Tursiops truncatus]"
ENSG00000168546(GFRA2)	--	0.182960096	6	0.132430538	7	0.494047107	5	0.282653971	8	0.10929485	4	0.22432469	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GDNF/GAS1 domain	GDNF family receptor alpha-2 (Precursor) GN=GFRA2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: GDNF family receptor alpha-2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000168556(ING2)	--	6.351678	257	5.436308	212	6.9625	266	5.4386	195	6.298375	213	5.88941	207	0.766293907	-0.426190876	normal	0.965745425	-0.014533961	normal	0.847805621	-0.367710693	normal	0.375580777	-0.277865761	normal	--	--	--	--	--	[B]	Chromatin structure and dynamics	Inhibitor of growth proteins N-terminal histone-binding;; PHD-finger	Inhibitor of growth protein 2 GN=ING2 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: inhibitor of growth protein 2 isoform X1 [Sus scrofa]
ENSG00000168564(CDKN2AIP)	--	5.112001	230	4.996263803	223	5.395429	242	7.071284608	316	6.851034881	307	5.653721	249	0.739003036	0.425027456	normal	0.72051361	0.43723166	normal	0.966730269	0.032646128	normal	0.276794376	0.305594158	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3469)	CDKN2A-interacting protein GN=CDKN2AIP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: CDKN2A-interacting protein [Odobenus rosmarus divergens]
ENSG00000168566(SNRNP48)	--	5.250406	336	6.626793713	426	6.40537381	404	7.37626	477	6.588377	422	5.908581276	379	0.533186405	0.472872882	normal	0.968885275	-0.034912465	normal	0.964917696	-0.100062093	normal	0.721029296	0.110482683	normal	--	--	--	K13156|0|ptr:462421|SNRNP48; small nuclear ribonucleoprotein 48kDa (U11/U12); K13156 U11/U12 small nuclear ribonucleoprotein 48 kDa protein (A)	--	--	--	U11-48K-like CHHC zinc finger	U11/U12 small nuclear ribonucleoprotein 48 kDa protein GN=SNRNP48 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U11/U12 small nuclear ribonucleoprotein 48 kDa protein [Ceratotherium simum simum]
ENSG00000168569(TMEM223)	--	16.456021	286	15.715685	291	17.219951	304	19.737257	351	16.08266	278	16.929517	300	0.920735203	0.263344848	normal	0.963258934	-0.086898731	normal	0.967599124	-0.027263735	normal	0.892604815	0.054863212	normal	--	--	--	--	--	--	--	Transmembrane protein 223	Transmembrane protein 223 GN=TMEM223 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 223 [Equus caballus]
ENSG00000168575(SLC20A2)	--	13.898124	579	11.10762312	522	14.39920405	571	9.612376772	428	8.771296975	416	10.56155779	483	0.524158614	-0.465342386	normal	0.837996523	-0.347761547	normal	0.928231549	-0.249040955	normal	0.083250634	-0.354168308	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: inorganic phosphate transmembrane transporter activity (GO:0005315);; Biological Process: phosphate ion transport (GO:0006817);; Cellular Component: membrane (GO:0016020);; 	"K14640|0|hsa:6575|SLC20A2, GLVR-2, GLVR2, IBGC1, IBGC3, MLVAR, PIT-2, PIT2, RAM1; solute carrier family 20 (phosphate transporter), member 2; K14640 solute carrier family 20 (sodium-dependent phosphate transporter) (A)"	--	[P]	Inorganic ion transport and metabolism	Phosphate transporter family	Sodium-dependent phosphate transporter 2 GN=SLC20A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transporter 2 isoform X1 [Loxodonta africana]
ENSG00000168589(DYNLRB2)	--	0	0	0	0	0.488009	1	0.239474967	1	0.759806	2	0.43727968	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10419|1.78843e-63|ptr:454263|DYNLRB2; dynein, light chain, roadblock-type 2; K10419 dynein light chain roadblock-type (A)"	--	[DN]	"Cell cycle control, cell division, chromosome partitioning;; Cell motility"	Roadblock/LC7 domain	Dynein light chain roadblock-type 2 GN=DYNLRB2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	"hypothetical protein M91_21375, partial [Bos mutus]"
ENSG00000168591(TMUB2)	--	28.97488125	961	25.73200212	904	28.2570982	1012	24.3947848	819	25.63438866	872	29.30437947	999	0.929285452	-0.261052534	normal	0.975525367	-0.073296339	normal	0.979414562	-0.026903684	normal	0.609109298	-0.117390058	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ubiquitin family	Transmembrane and ubiquitin-like domain-containing protein 2 GN=TMUB2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane and ubiquitin-like domain-containing protein 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000168610(STAT3)	--	53.5595666	5316	53.40138583	5359	53.483423	5382	55.54129465	5609	52.3201485	5186	66.7178343	6680	0.993601548	0.046557115	normal	0.992829166	-0.068748445	normal	0.96210105	0.303337622	normal	0.664411696	0.101398528	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	K04692|0|myb:102239853|STAT3; signal transducer and activator of transcription 3 (acute-phase response factor); K04692 signal transducer and activator of transcription 3 (A)	Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Toxoplasmosis (ko05145);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Pancreatic cancer (ko05212);; Acute myeloid leukemia (ko05221);; Inflammatory bowel disease (IBD) (ko05321)	[KT]	Transcription;; Signal transduction mechanisms	"STAT protein, DNA binding domain;; STAT protein, all-alpha domain;; STAT protein, protein interaction domain;; SH2 domain"	Signal transducer and activator of transcription 3 GN=STAT3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: signal transducer and activator of transcription 3 isoform X1 [Myotis lucifugus]
ENSG00000168612(ZSWIM1)	--	5.03239	223	4.87391	217	4.01504	186	4.87859	209	5.39116	234	5.22733	231	0.96066657	-0.123493898	normal	0.962801332	0.0868043	normal	0.910069787	0.302090779	normal	0.845329298	0.085446013	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	SWIM zinc finger	Zinc finger SWIM domain-containing protein 1 GN=ZSWIM1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: zinc finger SWIM domain-containing protein 1 [Galeopterus variegatus]
ENSG00000168615(ADAM9)	--	138.696253	9111	157.563007	10396	142.8508127	9199	223.3229369	14770	198.8986793	12954	192.185506	12562	0.025516966	0.666067247	normal	0.979473928	0.295903925	normal	0.820559673	0.441163484	normal	0.004842386	0.467080909	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K06834|0|hsa:8754|ADAM9, CORD9, MCMP, MDC9, Mltng; ADAM metallopeptidase domain 9; K06834 disintegrin and metalloproteinase domain-containing protein 9 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; ADAM cysteine-rich;; Disintegrin;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 9 (Precursor) GN=ADAM9 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	disintegrin and metalloproteinase domain-containing protein 9 precursor [Canis lupus familiaris] 
ENSG00000168619(ADAM18)	--	0.0677162	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K16909|0|ptr:464132|ADAM18; disintegrin and metalloproteinase domain-containing protein 18; K16909 disintegrin and metalloproteinase domain-containing protein 18 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; Reprolysin family propeptide;; ADAM cysteine-rich;; Disintegrin;; Metallo-peptidase family M12B Reprolysin-like	Disintegrin and metalloproteinase domain-containing protein 18 (Precursor) GN=ADAM18 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 18 [Equus caballus]
ENSG00000168621(GDNF)	--	0.014011644	1	0.068707452	5	0	0	0.027808432	2	0.040934877	2	0.013875739	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K05452|1.46906e-130|pps:100969352|GDNF; glial cell derived neurotrophic factor; K05452 glial cell derived neurotrophic factor (A)	--	--	--	Transforming growth factor beta like domain	Glial cell line-derived neurotrophic factor (Precursor) GN=GDNF OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: glial cell line-derived neurotrophic factor isoform X1 [Camelus bactrianus]
ENSG00000168631(DPCR1)	--	0.034022975	3	0.030396198	5	0.023687488	3	0.017491996	2	0	0	0.067408248	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Mucin, catalytic, TM and cytoplasmic tail region"	Diffuse panbronchiolitis critical region protein 1 (Precursor) GN=DPCR1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: diffuse panbronchiolitis critical region protein 1-like [Equus caballus]
ENSG00000168634(WFDC13)	--	0	0	0	0	0	0	0.0458092	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	WAP four-disulfide core domain protein 13 (Precursor) GN=WFDC13 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"PREDICTED: WAP four-disulfide core domain protein 13, partial [Galeopterus variegatus]"
ENSG00000168646(AXIN2)	--	5.867959	517	3.116934302	282	3.149661984	283	1.4990984	117	3.231383199	281	1.449896455	112	0	-2.159701149	down	0.966248672	-0.026409712	normal	1.94E-07	-1.333856652	down	0.134264606	-1.106359631	normal	--	--	--	"K04385|0|hsa:8313|AXIN2, AXIL, ODCRCS; axin 2; K04385 axin 2 (A)"	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Endometrial cancer (ko05213);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	DIX domain;; Regulator of G protein signaling domain;; Axin beta-catenin binding domain	Axin-2 GN=AXIN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: axin-2 isoform X1 [Galeopterus variegatus]
ENSG00000168653(NDUFS5)	--	205.6314	1220	225.232	1374	232.046	1426	223.1512	1419	242.699	1434	243.042	1484	0.96678832	0.186942732	normal	0.982434046	0.040193159	normal	0.982998573	0.049174545	normal	0.706880123	0.088596894	normal	--	--	--	"K03938|1.30705e-73|ptr:456776|NDUFS5; NADH dehydrogenase (ubiquinone) Fe-S protein 5, 15kDa (NADH-coenzyme Q reductase); K03938 NADH dehydrogenase (ubiquinone) Fe-S protein 5 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"NADH:ubiquinone oxidoreductase, NDUFS5-15kDa;; Cytochrome c oxidase biogenesis protein Cmc1 like"	NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 GN=NDUFS5 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 [Elephantulus edwardii]
ENSG00000168661(ZNF30)	--	4.635599725	206	2.871179234	145	3.416538526	172	3.33690165	173	3.944999466	174	4.005500895	192	0.92430174	-0.280418775	normal	0.941557261	0.2393267	normal	0.958457915	0.149164432	normal	0.974413286	0.022626818	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:90075|ZNF30, KOX28; zinc finger protein 30; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; XPA protein N-terminal;; NTF2 fold immunity protein;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; NifU-like N terminal domain"	Zinc finger protein 30 GN=ZNF30 OS=Homo sapiens (Human) PE=2 SV=5	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 30 [Ceratotherium simum simum]
ENSG00000168672(FAM84B)	--	2.22525	176	2.593613	212	2.465655	193	4.718571	387	4.882197	399	7.05004	543	7.17E-06	1.099296678	up	0.001093859	0.886217173	normal	5.62E-12	1.47685561	up	2.25E-05	1.173499702	up	--	--	--	--	--	--	--	Lecithin retinol acyltransferase	Protein FAM84B GN=FAM84B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM84B [Galeopterus variegatus] 
ENSG00000168675(LDLRAD4)	--	0.327603882	20	0.218573615	21	0.586093853	13	2.016589611	95	2.146774395	156	1.965907801	100	1.46E-07	2.134805042	up	4.44E-16	2.786075808	up	1.19E-11	2.798509824	up	2.65E-07	2.678877394	up	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Low-density lipoprotein receptor domain class A	Low-density lipoprotein receptor class A domain-containing protein 4 GN=LDLRAD4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor class A domain-containing protein 4 isoform X1 [Tupaia chinensis]
ENSG00000168676(KCTD19)	--	1.523906914	33	0.311857033	6	0.235747	15	0.5743248	7	1.175738655	14	0.433989	14	0.028175864	-2.043782167	normal	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	--	--	BTB/POZ domain	BTB/POZ domain-containing protein KCTD19 GN=KCTD19 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: BTB/POZ domain-containing protein KCTD19 [Oryctolagus cuniculus]
ENSG00000168679(SLC16A4)	--	27.170945	937	22.727134	800	22.75710538	775	29.045543	992	35.328941	1201	32.86199796	1139	0.978114707	0.051376931	normal	0.144044737	0.56386222	normal	0.174954376	0.546323459	normal	0.018825571	0.386666934	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08181|0|pps:100968424|SLC16A4; solute carrier family 16, member 4; K08181 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 4 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 5 GN=SLC16A4 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 5 [Vicugna pacos]
ENSG00000168685(IL7R)	--	0.051416988	4	0	0	0.643191375	5	1.820482271	128	1.34450429	100	1.487972288	70	0	4.521880681	up	0	6.058261716	up	7.87E-11	3.449713901	up	4.84E-14	5.028349708	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05072|0|hsa:3575|IL7R, CD127, CDW127, IL-7R-alpha, IL7RA, ILRA; interleukin 7 receptor; K05072 interleukin 7 receptor (A)"	Cytokine-cytokine receptor interaction (ko04060);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Primary immunodeficiency (ko05340)	--	--	Fibronectin type III domain	Interleukin-7 receptor subunit alpha (Precursor) GN=IL7R OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-7 receptor subunit alpha [Galeopterus variegatus]
ENSG00000168701(TMEM208)	--	40.41351507	376	44.36699245	427	43.39990939	414	47.299408	453	40.90087108	378	51.041141	481	0.932517107	0.237062617	normal	0.946593918	-0.196536036	normal	0.944693745	0.207411181	normal	0.78854852	0.087377081	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF788)	Transmembrane protein 208 GN=TMEM208 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 208 [Equus caballus]
ENSG00000168702(LRP1B)	--	0.225286469	45	0.172021567	26	0.290160297	48	0.075723022	8	0.093690605	25	0.146906029	39	0.000336763	-2.314674995	down	0.985491421	-0.073641546	normal	0.971575717	-0.297437113	normal	0.361656164	-0.741440336	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; Low-density lipoprotein receptor repeat class B;; Coagulation Factor Xa inhibitory site;; SMP-30/Gluconolaconase/LRE-like region;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; EGF-like domain	Low-density lipoprotein receptor-related protein 1B (Precursor) GN=LRP1B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 1B [Canis lupus familiaris]
ENSG00000168710(AHCYL1)	--	49.69777161	3550	46.5166775	3374	45.24564953	3245	35.98552795	2576	41.76463507	2963	37.66039434	2687	0.41952671	-0.493266863	normal	0.977372909	-0.208727987	normal	0.952886662	-0.280369783	normal	0.040829495	-0.327019221	normal	[H]	Coenzyme transport and metabolism	Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; 	K01251|0|ssc:100512899|adenosylhomocysteinase-like protein 1; K01251 adenosylhomocysteinase [EC:3.3.1.1] (A)	Cysteine and methionine metabolism (ko00270)	[H]	Coenzyme transport and metabolism	"S-adenosyl-L-homocysteine hydrolase;; S-adenosyl-L-homocysteine hydrolase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; Acetohydroxy acid isomeroreductase, catalytic domain;; Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain"	Putative adenosylhomocysteinase 2 GN=AHCYL1 OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: putative adenosylhomocysteinase 2 isoform X1 [Condylura cristata]
ENSG00000168724(DNAJC21)	--	13.82381195	1053	11.2445172	964	11.56412797	966	14.10007573	1062	12.74990014	983	13.3097752	1012	0.980070908	-0.018527016	normal	0.978750983	0.006721271	normal	0.978178682	0.058732915	normal	0.968742065	0.013933988	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09506|0|pon:100459375|DNAJC21; DnaJ (Hsp40) homolog, subfamily C, member 21; K09506 DnaJ homolog subfamily A member 5 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; Zinc-finger of C2H2 type	DnaJ homolog subfamily C member 21 GN=DNAJC21 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 21 [Equus przewalskii]
ENSG00000168734(PKIG)	--	17.50409733	413	16.64338509	398	17.73122217	421	19.27066078	458	20.49250169	479	21.079212	502	0.963618708	0.117956743	normal	0.928661641	0.244981158	normal	0.929531548	0.244769535	normal	0.42207014	0.203234202	normal	--	--	--	--	--	--	--	cAMP-dependent protein kinase inhibitor	cAMP-dependent protein kinase inhibitor gamma GN=PKIG OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	cAMP-dependent protein kinase inhibitor gamma [Sus scrofa] 
ENSG00000168743(NPNT)	--	0.4485818	9	0.152536002	12	0.254860904	16	1.4837015	14	0.2353245	13	0.1530073	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: membrane (GO:0016020);; 	K06824|0|cfa:487891|NPNT; nephronectin; K06824 nephronectin (A)	--	[T]	Signal transduction mechanisms	MAM domain;; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Coagulation Factor Xa inhibitory site;; EGF domain;; EGF-like domain	Nephronectin (Precursor) GN=NPNT OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: nephronectin isoform X2 [Mustela putorius furo] 
ENSG00000168748(CA7)	--	0.140030003	4	0.0344943	1	0	0	0.069857307	2	0.034072103	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	K01672|0|nle:100603064|CA7; carbonic anhydrase VII; K01672 carbonic anhydrase [EC:4.2.1.1] (A)	Nitrogen metabolism (ko00910)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase 7 GN=CA7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carbonic anhydrase 7 [Mustela putorius furo] 
ENSG00000168758(SEMA4C)	--	10.96473459	703	10.33771436	680	9.807851295	631	5.579718628	346	6.553129	426	7.186391	453	1.14E-06	-1.050240481	down	0.017394683	-0.694138668	normal	0.442338708	-0.485041944	normal	1.64E-05	-0.73778785	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06521|0|hsa:54910|SEMA4C, M-SEMA-F, SEMACL1, SEMAF, SEMAI; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C; K06521 semaphorin 4 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-4C (Precursor) GN=SEMA4C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: semaphorin-4C [Vicugna pacos]
ENSG00000168763(CNNM3)	--	7.588001	547	9.075052	665	7.748406	554	5.255344	377	5.903737	404	7.199981	539	0.190216256	-0.565881741	normal	0.007002802	-0.738248136	normal	0.971752117	-0.047759965	normal	0.066032646	-0.44026861	normal	[R]	General function prediction only	--	"K16302|0|hsa:26505|CNNM3, ACDP3; cyclin and CBS domain divalent metal cation transport mediator 3; K16302 metal transporter CNNM (A)"	--	[S]	Function unknown	Domain of unknown function DUF21;; CBS domain	Metal transporter CNNM3 GN=CNNM3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: metal transporter CNNM3 isoform X1 [Sus scrofa]
ENSG00000168769(TET2)	--	1.671309436	346	2.076630996	430	1.762935888	353	1.6709973	345	1.791613756	376	2.003844344	419	0.968079886	-0.034852949	normal	0.940961489	-0.214224134	normal	0.932246761	0.238053476	normal	0.989936683	-0.006822456	normal	--	--	--	--	--	--	--	Oxygenase domain of the 2OGFeDO superfamily	Methylcytosine dioxygenase TET2 GN=TET2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: methylcytosine dioxygenase TET2 [Panthera tigris altaica]
ENSG00000168772(CXXC4)	--	1.031600725	77	1.308109222	107	0.879242188	66	1.2270691	94	1.506249702	121	1.579895739	122	0.957809948	0.252406043	normal	0.961702663	0.153923022	normal	0.131108852	0.863284741	normal	0.348758594	0.409821129	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	"K03344|1.93441e-174|hsa:80319|CXXC4, IDAX; CXXC finger protein 4; K03344 Dvl-binding protein IDAX (A)"	Wnt signaling pathway (ko04310)	--	--	CXXC zinc finger domain	CXXC-type zinc finger protein 4 GN=CXXC4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: CXXC-type zinc finger protein 4 [Vicugna pacos]
ENSG00000168778(TCTN2)	--	8.73809929	395	10.2318132	472	8.583565	388	10.115842	470	9.097892768	416	11.215139	514	0.940056793	0.219193492	normal	0.945344272	-0.202936744	normal	0.747485419	0.39607479	normal	0.630235954	0.136528657	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1619)	Tectonic-2 (Precursor) GN=TCTN2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: tectonic-2 [Ceratotherium simum simum]
ENSG00000168779(SHOX2)	--	3.20863	144	3.2619948	135	2.798689863	118	1.968885711	83	1.824184	70	1.8777145	86	0.119479993	-0.814124228	normal	0.031496834	-0.95384907	normal	0.863974122	-0.457768789	normal	0.032799742	-0.753564937	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	K09331|0|ptr:460809|SHOX2; short stature homeobox 2; K09331 short stature homeobox protein (A)	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Short stature homeobox protein 2 GN=SHOX2 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	short stature homeobox protein 2 [Bos taurus] 
ENSG00000168781(PPIP5K1)	--	4.467616517	475	4.512170098	437	3.986455135	448	5.067344502	442	4.540121701	487	5.586858068	507	0.961813793	-0.13426305	normal	0.961164957	0.134421134	normal	0.955703243	0.169656917	normal	0.867818769	0.057678396	normal	--	--	Molecular Function: acid phosphatase activity (GO:0003993);; 	"K13024|0|hsa:9677|PPIP5K1, HISPPD2A, IP6K, IPS1, VIP1, hsVIP1; diphosphoinositol pentakisphosphate kinase 1 (EC:2.7.4.21 2.7.4.24); K13024 inositol hexakisphosphate/diphosphoinositol-pentakisphosphate kinase [EC:2.7.4.21 2.7.4.24] (A)"	--	[Z]	Cytoskeleton	Histidine phosphatase superfamily (branch 2)	Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 GN=PPIP5K1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 isoform 1 [Ceratotherium simum simum]
ENSG00000168785(TSPAN5)	--	10.47361796	556	8.998981979	480	9.388130017	494	16.55748105	846	14.94304574	787	11.95644193	633	0.126282094	0.573447428	normal	0.016149091	0.690188256	normal	0.831882867	0.34845836	normal	0.002369083	0.544548117	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17345|0|rno:362048|Tspan5, Tm4sf9, Tspan-5; tetraspanin 5; K17345 tetraspanin-5 (A)"	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-5 GN=TSPAN5 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	tetraspanin-5 [Bos taurus] 
ENSG00000168792(ABHD15)	--	17.8383	1095	17.4716	1088	16.4447	1027	16.8068	1042	16.6524	1021	14.389	891	0.976203088	-0.102260739	normal	0.974608737	-0.11296013	normal	0.95357664	-0.212893415	normal	0.514218899	-0.141635631	normal	[R]	General function prediction only	--	K13707|0|hsa:116236|ABHD15; abhydrolase domain containing 15 (EC:3.1.1.-); K13707 abhydrolase domain-containing protein 15 (A)	--	[R]	General function prediction only	Alpha/beta hydrolase family	Abhydrolase domain-containing protein 15 (Precursor) GN=ABHD15 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: abhydrolase domain-containing protein 15 [Equus caballus]
ENSG00000168795(ZBTB5)	--	5.068848	411	5.33331	440	4.99056272	399	5.750445	466	6.611382	529	7.623985	619	0.958791685	0.149833049	normal	0.929963687	0.243573252	normal	0.069291771	0.623347589	normal	0.098185022	0.348255701	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10492|0|hsa:9925|ZBTB5; zinc finger and BTB domain containing 5; K10492 zinc finger and BTB domain-containing protein 5 (A)	--	[R]	General function prediction only	BTB/POZ domain;; Zinc-finger double domain;; C2H2-type zinc finger	Zinc finger and BTB domain-containing protein 5 GN=ZBTB5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 5 isoform X1 [Mustela putorius furo] 
ENSG00000168802(CHTF8)	--	48.02410922	1900	42.69398469	1738	42.21407923	1972	44.27583235	1945	39.22817023	1761	52.94938839	2168	0.98650626	0.002936127	normal	0.985238986	-0.002457606	normal	0.982315152	0.12831988	normal	0.866607998	0.045595402	normal	--	--	--	--	--	--	--	--	Chromosome transmission fidelity protein 8 homolog isoform 2 GN=CHTF8 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: chromosome transmission fidelity protein 8 homolog isoform 2-like isoform X2 [Vicugna pacos]
ENSG00000168803(ADAL)	--	3.637737664	177	3.626843479	197	4.153285476	178	2.179923255	141	2.399115693	132	2.842321735	144	0.891674124	-0.355421114	normal	0.447140722	-0.593479378	normal	0.91680663	-0.311155044	normal	0.198457502	-0.425887447	normal	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: deaminase activity (GO:0019239);; 	--	--	[F]	Nucleotide transport and metabolism	Adenosine/AMP deaminase	Adenosine deaminase-like protein GN=ADAL OS=Homo sapiens (Human) PE=2 SV=2	F	Nucleotide transport and metabolism	PREDICTED: adenosine deaminase-like protein isoform X1 [Panthera tigris altaica] 
ENSG00000168806(LCMT2)	--	3.684480224	253	3.351450582	254	4.274330232	260	3.782940149	227	3.712380168	220	3.639970225	205	0.950226081	-0.186083534	normal	0.93815181	-0.227295952	normal	0.869055867	-0.348888218	normal	0.415494223	-0.255794677	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: methylation (GO:0032259);; 	"K15451|0|hsa:9836|LCMT2, PPM2, TYW4; leucine carboxyl methyltransferase 2 (EC:2.1.1.290 2.3.1.231); K15451 tRNA wybutosine-synthesizing protein 4 [EC:2.1.1.290 2.3.1.231] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Leucine carboxyl methyltransferase;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif"	tRNA wybutosine-synthesizing protein 4 GN=LCMT2 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	leucine carboxyl methyltransferase 2 (predicted) [Rhinolophus ferrumequinum]
ENSG00000168811(IL12A)	--	0.873511735	23	1.128802586	30	1.075221186	28	0.549335608	13	0.406293351	10	0.526873491	14	0.964333081	-0.783488476	normal	0.460799313	-1.472245469	normal	0.915464738	-0.935579135	normal	0.07979123	-1.151429695	normal	--	--	Molecular Function: interleukin-12 receptor binding (GO:0005143);; Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: growth factor activity (GO:0008083);; 	"K05406|8.41194e-158|hsa:3592|IL12A, CLMF, IL-12A, NFSK, NKSF1, P35; interleukin 12A; K05406 interleukin 12A (A)"	Cytokine-cytokine receptor interaction (ko04060);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Jak-STAT signaling pathway (ko04630);; Type I diabetes mellitus (ko04940);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Malaria (ko05144);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Inflammatory bowel disease (IBD) (ko05321);; Allograft rejection (ko05330)	--	--	Interleukin-12 alpha subunit	Interleukin-12 subunit alpha (Precursor) GN=IL12A OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: interleukin-12 subunit alpha [Galeopterus variegatus]
ENSG00000168813(ZNF507)	--	10.56611476	1420	11.70050617	1586	10.33629883	1377	9.028883006	1231	9.432725224	1240	11.13803091	1425	0.951370012	-0.23661716	normal	0.806199925	-0.37607252	normal	0.982823138	0.041097548	normal	0.312281383	-0.190865087	normal	--	--	--	--	--	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc finger, C2H2 type;; C2H2-type zinc-finger domain;; Zinc-finger double domain"	Zinc finger protein 507 GN=ZNF507 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 507 isoform X1 [Physeter catodon] 
ENSG00000168818(STX18)	--	5.982474026	271	6.792875785	296	6.769153514	307	8.5402	390	9.329415362	416	7.3123	332	0.511929573	0.492012519	normal	0.586312757	0.467536102	normal	0.96323531	0.104159642	normal	0.136926856	0.359342074	normal	--	--	--	K08492|0|pps:100989818|STX18; syntaxin 18; K08492 syntaxin 18 (A)	SNARE interactions in vesicular transport (ko04130);; Phagosome (ko04145)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE-complex protein Syntaxin-18 N-terminus	Syntaxin-18 GN=STX18 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-18 [Orcinus orca]
ENSG00000168824(NSG1)	--	0.090678501	2	0.269799	6	0.2229918	3	0.18281253	5	0.3446097	10	0.134033741	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: dopamine receptor signaling pathway (GO:0007212);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: clathrin light chain binding (GO:0032051);; Biological Process: clathrin coat assembly (GO:0048268);; 	--	--	--	--	D1 dopamine receptor-interacting protein (calcyon)	Neuron-specific protein family member 1 GN=NSG1 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	hypothetical protein PANDA_012460 [Ailuropoda melanoleuca]
ENSG00000168826(ZBTB49)	--	1.39926303	60	1.344143938	65	1.00229599	53	0.883638987	50	1.303761848	70	1.2240821	67	0.966633298	-0.285835709	normal	0.972856215	0.08361384	normal	0.95921308	0.321696367	normal	0.961743152	0.050597117	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; BTB/POZ domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; GAGA factor"	Zinc finger and BTB domain-containing protein 49 GN=ZBTB49 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 49 isoform X1 [Galeopterus variegatus]
ENSG00000168827(GFM1)	--	24.03978978	1488	25.79192898	1591	24.783881	1490	28.72370286	1776	28.37095818	1751	26.06279387	1602	0.960724625	0.224212674	normal	0.980365478	0.116712915	normal	0.981375298	0.096176217	normal	0.474071407	0.145249247	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K02355|0|hsa:85476|GFM1, COXPD1, EFG, EFG1, EFGM, EGF1, GFM, hEFG1; G elongation factor, mitochondrial 1; K02355 elongation factor G (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	"Elongation factor Tu GTP binding domain;; Elongation factor G, domain IV;; Elongation Factor G, domain II;; Elongation factor G C-terminus;; Elongation factor Tu domain 2"	"Elongation factor G, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03061} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: elongation factor G, mitochondrial [Myotis lucifugus]"
ENSG00000168828(OR13J1)	--	0.0520626	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:392309|OR13J1, OR9-2; olfactory receptor, family 13, subfamily J, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 13J1 GN=OR13J1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 13J1 [Galeopterus variegatus]
ENSG00000168843(FSTL5)	--	0.115797112	7	0.073491023	4	0.103470902	6	0.012154637	1	0.047481246	3	0.056106721	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Kazal-type serine protease inhibitor domain;; Immunoglobulin V-set domain;; Kazal-type serine protease inhibitor domain	Follistatin-related protein 5 (Precursor) GN=FSTL5 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: follistatin-related protein 5 isoform X1 [Ailuropoda melanoleuca]
ENSG00000168874(ATOH8)	--	1.81302	78	1.20489	53	1.50309	67	0.302458	13	0.607164	26	0.800665	35	4.06E-08	-2.480844722	down	0.506253569	-1.007045864	normal	0.462541553	-0.916008909	normal	0.001715582	-1.438204737	down	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09084|2.74407e-149|hsa:84913|ATOH8, HATH6, bHLHa21; atonal homolog 8 (Drosophila); K09084 atonal protein 8 (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Protein atonal homolog 8 GN=ATOH8 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: protein atonal homolog 8 [Bison bison bison]
ENSG00000168876(ANKRD49)	--	7.077661	183	5.654838	148	4.868998842	147	4.551854	165	5.5427187	170	6.683782	196	0.954549538	-0.178629495	normal	0.954434556	0.176824144	normal	0.841516817	0.403142621	normal	0.7748974	0.130860534	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[K]	Transcription	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 49 GN=ANKRD49 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ankyrin repeat domain-containing protein 49 [Ursus maritimus] 
ENSG00000168878(SFTPB)	--	0.014176763	1	0	0	0.01751102	0	0.028733987	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	--	--	[IG]	Lipid transport and metabolism;; Carbohydrate transport and metabolism	"Saposin-like type B, region 2;; Saposin A-type domain;; Saposin-like type B, region 1"	Pulmonary surfactant-associated protein B (Precursor) GN=SFTPB OS=Homo sapiens (Human) PE=1 SV=3	GI	Carbohydrate transport and metabolism;; Lipid transport and metabolism	PREDICTED: pulmonary surfactant-associated protein B [Galeopterus variegatus]
ENSG00000168883(USP39)	--	40.35990033	1667	39.1930102	1610	39.77039174	1620	33.928986	1387	31.73381313	1297	28.85494983	1190	0.919788339	-0.295819159	normal	0.88135342	-0.33295955	normal	0.540462286	-0.45282844	normal	0.022947142	-0.3597347	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K12847|0|hsa:10713|USP39, 65K, HSPC332, SAD1, SNRNP65; ubiquitin specific peptidase 39; K12847 U4/U6.U5 tri-snRNP-associated protein 2 (A)"	Spliceosome (ko03040)	[Z]	Cytoskeleton	Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein;; Ubiquitin carboxyl-terminal hydrolase	U4/U6.U5 tri-snRNP-associated protein 2 GN=USP39 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: U4/U6.U5 tri-snRNP-associated protein 2 [Bubalus bubalis]
ENSG00000168884(TNIP2)	--	16.266504	661	14.6877467	621	15.66408041	667	16.485805	671	16.141837	647	14.05220367	575	0.974789769	-0.009148663	normal	0.973069652	0.037656045	normal	0.94279474	-0.221873909	normal	0.832164389	-0.063605707	normal	--	--	--	--	--	--	--	TSG101 and ALIX binding domain of CEP55	TNFAIP3-interacting protein 2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TNFAIP3-interacting protein 2 [Ceratotherium simum simum]
ENSG00000168887(C2orf68)	--	16.36313	856	13.28488	705	16.13861	797	8.94857	462	9.34626	481	9.16498	492	3.09E-05	-0.918268709	normal	0.158254415	-0.571519017	normal	0.00998736	-0.702499488	normal	6.33E-06	-0.737423874	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0561	UPF0561 protein C2orf68 GN=C2orf68 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0561 protein C2orf68 homolog [Equus caballus]
ENSG00000168890(TMEM150A)	--	7.722893689	184	8.96699	232	7.755212895	184	7.225393276	169	8.54882449	192	8.428396758	201	0.958324853	-0.152188207	normal	0.913310115	-0.292346743	normal	0.961645619	0.118268011	normal	0.790144514	-0.115301604	normal	--	--	--	--	--	[S]	Function unknown	Frag1/DRAM/Sfk1 family	Transmembrane protein 150A (Precursor) GN=TMEM150A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 150A [Ochotona princeps]
ENSG00000168894(RNF181)	--	100.478999	604	77.61676	481	78.57019	491	85.976426	536	80.758566	493	68.372046	424	0.948430812	-0.202600295	normal	0.970689454	0.014080468	normal	0.940633858	-0.219222903	normal	0.605757742	-0.139237079	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	E3 ubiquitin-protein ligase RNF181 GN=RNF181 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF181-like isoform X2 [Sus scrofa] 
ENSG00000168899(VAMP5)	--	0.337111	3	0.322208	3	0	0	0.104061	1	0.217759	1	0.214234	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K08514|1.32278e-62|hsa:10791|VAMP5; vesicle-associated membrane protein 5; K08514 vesicle-associated membrane protein 5 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Synaptobrevin	Vesicle-associated membrane protein 5 GN=VAMP5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-associated membrane protein 5 [Leptonychotes weddellii]
ENSG00000168904(LRRC28)	--	20.14641847	420	13.47686348	326	19.92334546	416	12.7052063	307	12.77631988	283	15.13005643	346	0.525537445	-0.480915719	normal	0.937199252	-0.224378218	normal	0.913667543	-0.273013051	normal	0.168478613	-0.332652054	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 28 GN=LRRC28 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 28 isoform X1 [Galeopterus variegatus]
ENSG00000168906(MAT2A)	--	238.48313	10188	178.6513345	7920	188.274145	8055	165.82003	7201	183.363191	7786	155.9175326	6651	0.378692463	-0.531338108	normal	0.995049707	-0.046035778	normal	0.973867397	-0.284545874	normal	0.149397525	-0.295469466	normal	[H]	Coenzyme transport and metabolism	Molecular Function: methionine adenosyltransferase activity (GO:0004478);; Biological Process: S-adenosylmethionine biosynthetic process (GO:0006556);; 	"K00789|0|pale:102898454|MAT2A; methionine adenosyltransferase II, alpha; K00789 S-adenosylmethionine synthetase [EC:2.5.1.6] (A)"	Cysteine and methionine metabolism (ko00270);; Biosynthesis of amino acids (ko01230)	[H]	Coenzyme transport and metabolism	"S-adenosylmethionine synthetase, C-terminal domain;; S-adenosylmethionine synthetase, central domain;; S-adenosylmethionine synthetase, N-terminal domain"	S-adenosylmethionine synthase isoform type-2 GN=MAT2A OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	S-adenosylmethionine synthetase isoform type-2 [Pteropus alecto]
ENSG00000168907(PLA2G4F)	--	0	0	0.0169334	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipase activity (GO:0004620);; Biological Process: phospholipid catabolic process (GO:0009395);; 	"K16342|0|hsa:255189|PLA2G4F, PLA2G4FZ; phospholipase A2, group IVF (EC:3.1.1.4); K16342 cytosolic phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Platelet activation (ko04611);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Oxytocin signaling pathway (ko04921);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Lysophospholipase catalytic domain;; C2 domain	Cytosolic phospholipase A2 zeta GN=PLA2G4F OS=Homo sapiens (Human) PE=2 SV=3	I	Lipid transport and metabolism	PREDICTED: cytosolic phospholipase A2 zeta [Galeopterus variegatus]
ENSG00000168913(ENHO)	--	1.47619	24	1.9667	33	2.31591	39	0.482281	8	0.712947	11	0.900555	15	0.722287791	-1.448453815	normal	0.339830213	-1.483427134	normal	0.394180114	-1.302576537	normal	0.011782317	-1.516291871	normal	--	--	--	--	--	--	--	--	Adropin (Precursor) GN=ENHO OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	TPA: hypothetical protein BOS_9159 [Bos taurus]
ENSG00000168916(ZNF608)	--	1.34263666	174	1.495764086	211	1.303814641	154	1.677997633	223	2.492757	347	2.25555609	310	0.898426476	0.324587132	normal	0.061481928	0.692359422	normal	0.000264282	0.994029489	normal	0.034524216	0.686649483	normal	[KD]	"Transcription;; Cell cycle control, cell division, chromosome partitioning"	--	--	--	--	--	--	Zinc finger protein 608 GN=ZNF608 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: zinc finger protein 608-like [Trichechus manatus latirostris]
ENSG00000168917(SLC35G2)	--	14.00344539	364	16.14567081	439	16.61615698	424	9.713336704	242	9.872834963	265	10.02307911	272	0.152234257	-0.61654771	normal	0.013612262	-0.746309197	normal	0.079459872	-0.64584893	normal	0.001139001	-0.676196321	normal	--	--	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	EamA-like transporter family;; UAA transporter family	Solute carrier family 35 member G2 {ECO:0000312|HGNC:HGNC:28480} OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: solute carrier family 35 member G2 [Panthera tigris altaica]
ENSG00000168918(INPP5D)	--	0.089367104	9	0.098412946	8	0.120542565	10	0.210510982	19	0.606929334	31	0.133563673	12	--	--	--	0.172987769	1.753896425	normal	--	--	--	--	--	--	--	--	--	"K03084|0|hsa:3635|INPP5D, SHIP, SHIP-1, SHIP1, SIP-145, hp51CN, p150Ship; inositol polyphosphate-5-phosphatase, 145kDa (EC:3.1.3.86); K03084 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 1 [EC:3.1.3.86] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endonuclease/Exonuclease/phosphatase family;; SH2 domain	"Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 GN=INPP5D OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 isoform 2 [Ceratotherium simum simum]"
ENSG00000168924(LETM1)	--	16.0806	1704	15.8483	1711	17.6668	1905	17.0998	1810	16.55	1746	13.8764	1470	0.984735173	0.056182944	normal	0.985102687	0.007780434	normal	0.795281069	-0.381920133	normal	0.640130864	-0.103590378	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K17800|0|hsa:3954|LETM1; leucine zipper-EF-hand containing transmembrane protein 1; K17800 LETM1 and EF-hand domain-containing protein 1, mitochondrial (A)"	--	[S]	Function unknown	LETM1-like protein	"LETM1 and EF-hand domain-containing protein 1, mitochondrial (Precursor) GN=LETM1 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: LETM1 and EF-hand domain-containing protein 1, mitochondrial isoform X1 [Equus caballus] "
ENSG00000168936(TMEM129)	--	20.715539	859	19.63231	877	19.36188056	828	18.68885	800	20.041593	846	20.62888	881	0.969212923	-0.133243359	normal	0.975145418	-0.07321718	normal	0.975090418	0.081076234	normal	0.88850861	-0.041946298	normal	--	--	--	--	--	[S]	Function unknown	Putative transmembrane protein precursor	E3 ubiquitin-protein ligase TM129 GN=TMEM129 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 129 [Galeopterus variegatus]
ENSG00000168938(PPIC)	--	11.919	236	12.1555	243	10.7594	212	12.3939	248	12.4803	245	15.0004	296	0.966426741	0.040464015	normal	0.965997904	-0.009541983	normal	0.64417038	0.470389148	normal	0.623331118	0.170441473	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K09563|6.30341e-124|hsa:5480|PPIC, CYPC; peptidylprolyl isomerase C (cyclophilin C) (EC:5.2.1.8); K09563 peptidyl-prolyl isomerase C (cyclophilin C) [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase C GN=PPIC OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase C [Camelus dromedarius]
ENSG00000168939(SPRY3)	--	0.479412903	68	0.333465854	47	0.310483877	42	0.175362048	25	0.245523186	35	0.34091783	49	0.010681114	-1.419392336	normal	0.95834813	-0.430617029	normal	0.975780045	0.207188273	normal	0.350937408	-0.546077185	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	K17384|0|nle:100581235|protein sprouty homolog 3-like; K17384 protein sprouty homolog 3 (A)	--	--	--	Sprouty protein (Spry)	Protein sprouty homolog 3 GN=SPRY3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein sprouty homolog 3-like isoform X1 [Tupaia chinensis] 
ENSG00000168944(CEP120)	--	8.437596648	756	7.79651186	698	8.569048	761	7.204802721	648	8.18086712	737	8.435700975	756	0.929587122	-0.252669342	normal	0.973763226	0.056891066	normal	0.97628628	-0.017766239	normal	0.802100085	-0.069620847	normal	--	--	--	K16459|0|ggo:101141632|CEP120; centrosomal protein of 120 kDa isoform 1; K16459 centrosomal protein CEP120 (A)	--	--	--	Cep120 protein	Centrosomal protein of 120 kDa GN=CEP120 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: centrosomal protein of 120 kDa [Ceratotherium simum simum]
ENSG00000168952(STXBP6)	--	2.94745997	102	2.526193307	95	3.237642212	96	2.267484249	72	3.378591643	110	2.4043093	81	0.833947837	-0.523888572	normal	0.959977063	0.187304746	normal	0.95689338	-0.249126209	normal	0.75579935	-0.176549417	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K08519|2.95048e-156|pps:100990563|STXBP6; syntaxin binding protein 6 (amisyn); K08519 syntaxin-binding protein 6 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component SEC3 N-terminal PIP2 binding PH;; Synaptobrevin	Syntaxin-binding protein 6 GN=STXBP6 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-binding protein 6 isoform 1 [Dasypus novemcinctus] 
ENSG00000168955(TM4SF20)	--	0.273313709	9	0.180465464	6	0.364839	14	2.209853	80	3.1176827	105	5.777935	202	5.06E-10	2.923760636	up	1.11E-16	3.806507104	up	0	3.705776041	up	0.000480207	3.721041457	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	L6 membrane protein	Transmembrane 4 L6 family member 20 GN=TM4SF20 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane 4 L6 family member 20 [Ursus maritimus]
ENSG00000168958(MFF)	--	64.7276109	1646	73.70534706	1830	72.24652294	1739	35.96414465	909	34.65223929	925	45.04095858	1195	2.39E-05	-0.88631356	normal	6.16E-07	-1.004553589	down	0.159220735	-0.548959386	normal	6.38E-09	-0.804228742	normal	--	--	--	--	--	--	--	Mitochondrial and peroxisomal fission factor Mff	Mitochondrial fission factor GN=MFF OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial fission factor isoform X2 [Tupaia chinensis]
ENSG00000168959(GRM5)	--	0	0	0.023979918	2	0	0	0.007432008	1	0	0	0.007392159	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04604|0|ptr:451472|GRM5; glutamate receptor, metabotropic 5; K04604 metabotropic glutamate receptor 5 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Gap junction (ko04540);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Huntington's disease (ko05016)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Homer-binding domain of metabotropic glutamate receptor;; Nine Cysteines Domain of family 3 GPCR;; Periplasmic binding protein	Metabotropic glutamate receptor 5 (Precursor) GN=GRM5 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: metabotropic glutamate receptor 5 isoform X1 [Lipotes vexillifer]
ENSG00000168961(LGALS9)	--	0.37650225	11	0.108025468	6	0.197845541	7	0.104762304	3	0.21666763	7	0.144083877	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	K10093|0|ptr:454519|LGALS9; galectin-9; K10093 galectin-9 (A)	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-9 GN=LGALS9 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: galectin-9 isoform X3 [Camelus dromedarius]
ENSG00000168970(JMJD7-PLA2G4B)	--	3.715885639	231	4.8883213	239	4.169937378	205	2.794270694	153	3.93660347	169	3.241816819	191	0.291452172	-0.620086761	normal	0.580372646	-0.517499071	normal	0.962362106	-0.109505609	normal	0.163058589	-0.416689183	normal	--	--	Molecular Function: phospholipase activity (GO:0004620);; Biological Process: phospholipid catabolic process (GO:0009395);; 	"K16342|0|hsa:8681|JMJD7-PLA2G4B, HsT16992, cPLA2-beta; JMJD7-PLA2G4B readthrough; K16342 cytosolic phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Platelet activation (ko04611);; Fc epsilon RI signaling pathway (ko04664);; Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Oxytocin signaling pathway (ko04921);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Cupin-like domain;; Lysophospholipase catalytic domain;; C2 domain	Cytosolic phospholipase A2 beta GN=PLA2G4B OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: cytosolic phospholipase A2 beta isoform X1 [Myotis lucifugus]
ENSG00000168993(CPLX1)	--	0.815842644	26	0.863319957	30	0.524793766	18	0.202827313	7	0.364730765	12	0.338708417	6	0.379620633	-1.716830834	normal	0.708126154	-1.241356227	normal	--	--	--	--	--	--	--	--	Biological Process: neurotransmitter transport (GO:0006836);; Molecular Function: syntaxin binding (GO:0019905);; 	"K15294|4.71574e-53|hsa:10815|CPLX1, CPX-I, CPX1; complexin 1; K15294 complexin-1/2 (A)"	Synaptic vesicle cycle (ko04721)	--	--	Synaphin protein	Complexin-1 GN=CPLX1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: complexin-1 [Felis catus] 
ENSG00000168994(PXDC1)	--	8.053873	293	8.884207797	340	8.361064	305	12.39149425	463	14.7074959	542	14.59382226	539	0.096324408	0.626644707	normal	0.058567114	0.649025851	normal	0.001892924	0.810123115	normal	0.000242356	0.698221756	normal	--	--	Molecular Function: phosphatidylinositol binding (GO:0035091);; 	--	--	--	--	PX domain	PX domain-containing protein 1 GN=PXDC1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: PX domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000169016(E2F6)	--	15.655889	843	16.11905585	878	14.13384342	761	10.018865	548	10.724834	575	10.237109	552	0.0281675	-0.650705604	normal	0.047954543	-0.630732409	normal	0.477974405	-0.470417134	normal	0.000338147	-0.588706505	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K09390|1.25195e-180|ptr:470148|E2F6; E2F transcription factor 6; K09390 transcription factor E2F6 (A)	--	[K]	Transcription	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F6 GN=E2F6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor E2F6 isoform X1 [Vicugna pacos]
ENSG00000169018(FEM1B)	--	13.94063	1520	15.04846	1646	13.06143	1402	15.104172	1630	16.40288	1783	15.80662	1723	0.98302826	0.069900142	normal	0.982350347	0.093832965	normal	0.926426921	0.288863374	normal	0.465152951	0.147864832	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10349|0|ptr:467716|FEM1B; fem-1 homolog b (C. elegans); K10349 Fem-1 homolog b (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Protein fem-1 homolog B GN=FEM1B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein fem-1 homolog B [Orycteropus afer afer]
ENSG00000169019(COMMD8)	--	12.472447	252	18.646974	379	14.37340321	287	14.85989	309	15.13367	305	14.65817	297	0.923249688	0.261906846	normal	0.864831139	-0.333329253	normal	0.967042047	0.040908845	normal	0.947133427	-0.032598907	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 8 GN=COMMD8 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COMM domain-containing protein 8 [Ceratotherium simum simum]
ENSG00000169020(ATP5I)	--	194.009	263	198.016	280	211.53	311	237.903	381	204.734	279	224.142	325	0.486430824	0.501449841	normal	0.966216273	-0.026445178	normal	0.966873788	0.05497219	normal	0.547539705	0.184305439	normal	--	--	--	"K02129|1.53887e-28|ptr:461042|ATP5I; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E; K02129 F-type H+-transporting ATPase subunit e (A)"	Oxidative phosphorylation (ko00190)	[C]	Energy production and conversion	ATP synthase E chain	"ATP synthase subunit e, mitochondrial GN=ATP5I OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: ATP synthase subunit e, mitochondrial [Ceratotherium simum simum]"
ENSG00000169021(UQCRFS1)	--	74.89680097	3968	70.21130071	3754	76.15670091	4003	75.567011	4026	76.91550088	4061	78.0264401	4131	0.992152688	-0.009893314	normal	0.990254046	0.091944202	normal	0.992028183	0.037104203	normal	0.891108288	0.038388805	normal	[C]	Energy production and conversion	"Molecular Function: ubiquinol-cytochrome-c reductase activity (GO:0008121);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: 2 iron, 2 sulfur cluster binding (GO:0051537);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00411|0|hsa:7386|UQCRFS1, RIP1, RIS1, RISP, UQCR5; ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 (EC:1.10.2.2); K00411 ubiquinol-cytochrome c reductase iron-sulfur subunit [EC:1.10.2.2] (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"Ubiquinol-cytochrome c reductase 8 kDa, N-terminal;; Ubiquinol cytochrome reductase transmembrane region;; Rieske [2Fe-2S] domain"	Cytochrome b-c1 complex subunit 11 (Precursor) GN=UQCRFS1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	"PREDICTED: cytochrome b-c1 complex subunit Rieske, mitochondrial [Ursus maritimus]"
ENSG00000169026(MFSD7)	--	0.280209	9	0.029796354	1	0.1955746	5	0.188546492	6	0.0827591	1	0.371682023	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12306|0|hsa:84179|MFSD7; major facilitator superfamily domain containing 7; K12306 MFS transporter, FLVCR family, MFS-domain-containing protein 7 (A)"	--	[R]	General function prediction only	Major Facilitator Superfamily	Major facilitator superfamily domain-containing protein 7 GN=MFSD7 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: major facilitator superfamily domain-containing protein 7 [Tupaia chinensis] 
ENSG00000169031(COL4A3)	--	1.736130107	218	1.826703896	208	1.2580674	163	0.803768929	117	1.150063045	156	1.148718095	156	0.005411518	-0.919654135	normal	0.792095926	-0.432816848	normal	0.965901463	-0.070944495	normal	0.126497932	-0.478018642	normal	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Cellular Component: collagen trimer (GO:0005581);; 	"K06237|0|hsa:1285|COL4A3; collagen, type IV, alpha 3 (Goodpasture antigen); K06237 collagen, type IV, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; C-terminal tandem repeated domain in type 4 procollagen	Tumstatin (Precursor) GN=COL4A3 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: collagen alpha-3(IV) chain isoform X2 [Bubalus bubalis]
ENSG00000169032(MAP2K1)	--	30.94081134	1727	33.178	1740	32.86926	1856	47.29896166	2498	32.79025	1736	32.07133064	1763	0.347728709	0.501300447	normal	0.985004822	-0.024725402	normal	0.983973974	-0.082386791	normal	0.653510869	0.149716654	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04368|0|bom:102280670|MAP2K1; mitogen-activated protein kinase kinase 1; K04368 mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; Vascular smooth muscle contraction (ko04270);; Dorso-ventral axis formation (ko04320);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Toll-like receptor signaling pathway (ko04620);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Prion diseases (ko05020);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Dual specificity mitogen-activated protein kinase kinase 1 GN=MAP2K1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dual specificity mitogen-activated protein kinase kinase 1 [Ceratotherium simum simum] 
ENSG00000169035(KLK7)	--	0	0	0.24475198	7	0.112420585	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K08668|3.03732e-163|ggo:101148068|KLK7; kallikrein-7; K08668 kallikrein 7 (chymotryptic, stratum corneum) [EC:3.4.21.117] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin	Kallikrein-7 (Precursor) GN=KLK7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: kallikrein-7 [Galeopterus variegatus]
ENSG00000169045(HNRNPH1)	--	157.7962928	5274	201.1571371	6445	164.6029934	5201	190.1371395	6163	182.2037947	5555	186.9006163	5696	0.987104738	0.193850677	normal	0.98198139	-0.235760353	normal	0.9915725	0.122834527	normal	0.9508736	0.019803027	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K12898|0|ngi:103749378|Hnrnph1; heterogeneous nuclear ribonucleoprotein H1 (H); K12898 heterogeneous nuclear ribonucleoprotein F/H (A)	--	[A]	RNA processing and modification	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNPHF zinc finger;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"Heterogeneous nuclear ribonucleoprotein H, N-terminally processed GN=HNRNPH1 OS=Homo sapiens (Human) PE=1 SV=4"	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein H isoform X1 [Camelus dromedarius]
ENSG00000169047(IRS1)	--	28.2723522	3675	27.097184	3496	30.24502001	3873	27.14829036	3650	26.23468	3466	24.03128003	3095	0.991330554	-0.040662991	normal	0.990801731	-0.033845384	normal	0.922148146	-0.331658348	normal	0.519151941	-0.134657866	normal	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	"K16172|0|hsa:3667|IRS1, HIRS-1; insulin receptor substrate 1; K16172 insulin receptor substrate 1 (A)"	cGMP-PKG signaling pathway (ko04022);; FoxO signaling pathway (ko04068);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; MicroRNAs in cancer (ko05206)	--	--	PTB domain (IRS-1 type);; PH domain	Insulin receptor substrate 1 GN=IRS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	insulin receptor substrate 1 [Sus scrofa]
ENSG00000169057(MECP2)	--	14.23751684	1977	21.43701417	2129	13.07260505	1945	16.41617126	1964	13.18762771	2168	14.50690058	2137	0.986312392	-0.040318767	normal	0.987185036	0.004758899	normal	0.982225758	0.127430755	normal	0.913597685	0.030046459	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; 	K11588|0|lve:103074598|MECP2; methyl CpG binding protein 2 (Rett syndrome); K11588 methyl CpG binding protein 2 (A)	--	[KB]	Transcription;; Chromatin structure and dynamics	Methyl-CpG binding domain	Methyl-CpG-binding protein 2 GN=MECP2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: methyl-CpG-binding protein 2 [Lipotes vexillifer]
ENSG00000169062(UPF3A)	--	12.925742	693	16.68995	723	12.49701	695	14.22937	758	13.601142	745	13.191472	712	0.971497185	0.098301809	normal	0.975202779	0.021773356	normal	0.97525529	0.026515816	normal	0.875334373	0.047969903	normal	--	--	--	K14328|0|ptr:452689|UPF3A; UPF3 regulator of nonsense transcripts homolog A (yeast); K14328 regulator of nonsense transcripts 3 (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Smg-4/UPF3 family	Regulator of nonsense transcripts 3A GN=UPF3A OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: regulator of nonsense transcripts 3A [Eptesicus fuscus]
ENSG00000169064(ZBBX)	--	0.099485538	6	0.016865341	1	0.033596032	1	0.074707253	5	0.121357752	7	0.108657226	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	B-box zinc finger	Zinc finger B-box domain-containing protein 1 GN=ZBBX OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: zinc finger B-box domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000169067(ACTBL2)	--	0	0	0	0	0	0	0.750546	32	0.3899	16	0.0936887	4	3.24E-06	4.433402816	up	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	--	--	--	[Z]	Cytoskeleton	Actin	Beta-actin-like protein 2 GN=ACTBL2 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: beta-actin-like protein 2-like [Elephantulus edwardii]
ENSG00000169071(ROR2)	--	1.00001419	79	0.883980231	70	1.25827412	96	0.033538979	2	0.117773127	9	0.149550816	10	9.99E-16	-4.533112564	down	1.58E-08	-2.785773838	down	8.82E-13	-3.090092032	down	1.43E-13	-3.561310147	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05123|0|hsa:4920|ROR2, BDB, BDB1, NTRKR2; receptor tyrosine kinase-like orphan receptor 2 (EC:2.7.10.1); K05123 receptor tyrosine kinase-like orphan receptor 2 [EC:2.7.10.1] (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Protein tyrosine kinase;; Protein kinase domain;; Kringle domain;; Fz domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Tyrosine-protein kinase transmembrane receptor ROR2 (Precursor) GN=ROR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase transmembrane receptor ROR2 [Ceratotherium simum simum]
ENSG00000169083(AR)	--	10.18782648	1666	11.29183359	1938	9.1670473	1648	6.327819183	1083	5.918322001	1076	7.198959824	1207	0.018049591	-0.651435962	normal	5.21E-05	-0.869392762	normal	0.522892039	-0.457089836	normal	2.84E-06	-0.662899284	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Molecular Function: androgen receptor activity (GO:0004882);; Molecular Function: steroid binding (GO:0005496);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: androgen receptor signaling pathway (GO:0030521);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08557|0|hsa:367|AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM; androgen receptor; K08557 androgen receptor (A)"	Oocyte meiosis (ko04114);; Pathways in cancer (ko05200);; Prostate cancer (ko05215)	[T]	Signal transduction mechanisms	"Androgen receptor;; Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Androgen receptor GN=AR OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	androgen receptor [Bos taurus] 
ENSG00000169084(DHRSX)	--	48.1433861	2272	54.78711841	2533	52.60355436	2265	31.40739075	1582	35.93470005	1826	44.5595295	1994	0.151300766	-0.552594938	normal	0.41430668	-0.493238352	normal	0.974168648	-0.192000354	normal	0.006574689	-0.408819352	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K11170|0|hsa:207063|DHRSX, CXorf11, DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6; dehydrogenase/reductase (SDR family) X-linked; K11170 dehydrogenase/reductase SDR family member X [EC:1.1.-.-] (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; NAD dependent epimerase/dehydratase family;; Enoyl-(Acyl carrier protein) reductase	Dehydrogenase/reductase SDR family member on chromosome X (Precursor) GN=DHRSX OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member on chromosome X-like isoform 2 [Odobenus rosmarus divergens]
ENSG00000169085(C8orf46)	--	0.249127234	13	0.221773986	11	0.42723155	15	0.718829235	35	0.946802547	47	0.488959924	26	0.539417421	1.301105874	normal	0.00366003	1.935207191	up	0.961424153	0.728852221	normal	0.013043547	1.448210192	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4648)	Uncharacterized protein C8orf46 GN=C8orf46 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C8orf46 homolog [Tupaia chinensis] 
ENSG00000169087(HSPBAP1)	--	2.00591	73	2.284930829	85	1.611108787	59	1.859426559	69	2.286554478	84	3.906303622	145	0.972901396	-0.109755808	normal	0.971023145	-0.037823141	normal	0.000247514	1.26757658	up	0.54254585	0.438124009	normal	--	--	--	--	--	[BT]	Chromatin structure and dynamics;; Signal transduction mechanisms	Cupin-like domain;; Cupin superfamily protein	HSPB1-associated protein 1 GN=HSPBAP1 OS=Homo sapiens (Human) PE=1 SV=1	BT	Chromatin structure and dynamics;; Signal transduction mechanisms	PREDICTED: HSPB1-associated protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000169093(ASMTL)	--	34.82137	1438	18.98449	814	22.233461	971	8.794533724	370	14.523736	607	4.836597	204	0	-1.984780634	down	0.589214478	-0.443800285	normal	0	-2.250746307	down	0.007281064	-1.470600226	down	[D]	"Cell cycle control, cell division, chromosome partitioning"	Molecular Function: O-methyltransferase activity (GO:0008171);; Molecular Function: nucleoside-triphosphate diphosphatase activity (GO:0047429);; 	--	--	[R]	General function prediction only	Maf-like protein;; O-methyltransferase;; Methyltransferase domain	N-acetylserotonin O-methyltransferase-like protein GN=ASMTL OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: N-acetylserotonin O-methyltransferase-like protein [Galeopterus variegatus]
ENSG00000169100(SLC25A6)	--	385.571	11204	339.868	10373	356.794	10953	227.3293	6653	256.4969	7552	242.2547	7135	0.000622831	-0.782628228	normal	0.67909079	-0.479246827	normal	0.058726218	-0.626524159	normal	4.33E-05	-0.629098921	normal	--	--	--	"K05863|0|mcf:102129825|SLC25A6; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6; K05863 solute carrier family 25 (mitochondrial adenine nucleotide translocator), member 4/5/6/31 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Parkinson's disease (ko05012);; Huntington's disease (ko05016);; HTLV-I infection (ko05166)	[C]	Energy production and conversion	Mitochondrial carrier protein	"ADP/ATP translocase 3, N-terminally processed GN=SLC25A6 OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	PREDICTED: ADP/ATP translocase 3 [Pteropus alecto]
ENSG00000169105(CHST14)	--	12.31320109	549	12.00729196	542	12.74835091	551	11.07338117	490	10.39279137	448	10.42682205	462	0.949962904	-0.194280726	normal	0.896343872	-0.295312805	normal	0.920721121	-0.261665533	normal	0.262315496	-0.25140441	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08105|0|hsa:113189|CHST14, ATCS, D4ST1, EDSMC1, HNK1ST; carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 (EC:2.8.2.35); K08105 dermatan 4-sulfotransferase 1 [EC:2.8.2.35] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Sulfotransferase family	Carbohydrate sulfotransferase 14 GN=CHST14 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: carbohydrate sulfotransferase 14 [Felis catus]
ENSG00000169116(PARM1)	--	1.20448827	109	1.17289261	105	0.830432747	74	0.605114164	54	0.702743907	63	0.65068082	59	0.036381371	-1.023206476	normal	0.442951978	-0.7443973	normal	0.954234889	-0.327588103	normal	0.077842721	-0.731968735	normal	--	--	--	--	--	--	--	--	Prostate androgen-regulated mucin-like protein 1 (Precursor) GN=PARM1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: prostate androgen-regulated mucin-like protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000169118(CSNK1G1)	--	8.514481488	1154	11.48339663	1403	10.7759176	1302	9.9935248	1462	9.895497	1424	9.10081407	1326	0.900561153	0.310100319	normal	0.983022292	7.57E-06	normal	0.982569715	0.018039123	normal	0.639329075	0.104800519	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08958|0|mcf:101925308|CSNK1G1; Casein kinase I isoform gamma-1; K08958 casein kinase 1, gamma [EC:2.7.11.1] (A)"	Hedgehog signaling pathway (ko04340)	[T]	Signal transduction mechanisms	Protein kinase domain;; Casein kinase 1 gamma C terminal;; Protein tyrosine kinase	Casein kinase I isoform gamma-1 GN=CSNK1G1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: casein kinase I isoform gamma-1 isoform X1 [Ochotona princeps]
ENSG00000169122(FAM110B)	--	7.421557042	282	6.15078179	221	14.62389674	234	5.74130049	143	5.409083418	261	7.39097171	189	0.000323769	-1.002685561	down	0.941095124	0.217207914	normal	0.902038738	-0.314150193	normal	0.409208517	-0.333942496	normal	--	--	--	--	--	--	--	Centrosome-associated N terminus;; Centrosome-associated C terminus	Protein FAM110B GN=FAM110B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM110B [Ailuropoda melanoleuca] 
ENSG00000169126(ARMC4)	--	0.092176324	4	0.12785928	9	0.138580029	6	0	0	0.028326828	0	0.022924178	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT repeat;; Armadillo-like;; HEAT-like repeat;; Adaptin N terminal region;; Kinesin-associated protein (KAP);; Proteasome non-ATPase 26S subunit	Armadillo repeat-containing protein 4 GN=ARMC4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing protein 4 [Tupaia chinensis]
ENSG00000169129(AFAP1L2)	--	6.673091834	578	5.294161004	456	6.460294141	573	9.420952034	776	10.55805603	862	5.205330009	456	0.736222026	0.393249956	normal	8.90E-05	0.895033829	normal	0.850041627	-0.336794084	normal	0.461589107	0.359715928	normal	--	--	--	--	--	--	--	PH domain	Actin filament-associated protein 1-like 2 GN=AFAP1L2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: actin filament-associated protein 1-like 2 [Ceratotherium simum simum]
ENSG00000169131(ZNF354A)	--	5.936588057	304	5.126060254	261	5.4780775	277	5.640619431	293	4.649344	240	5.975159	305	0.964691038	-0.083572637	normal	0.956937154	-0.141586119	normal	0.959853426	0.129955454	normal	0.955958996	-0.028031331	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:6940|ZNF354A, EZNF, HEL104, HKL1, KID-1, KID1, TCF17; zinc finger protein 354A; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; TFIIH C1-like domain"	Zinc finger protein 354A GN=ZNF354A OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 354A isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000169136(ATF5)	--	26.38385956	734	29.732422	889	26.75207507	793	32.01477	854	27.850402	748	28.36979	814	0.957806851	0.1872601	normal	0.922430984	-0.270070136	normal	0.976736476	0.029361219	normal	0.952824638	-0.021471001	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09044|6.41687e-99|hsa:22809|ATF5, ATFX, HMFN0395; activating transcription factor 5; K09044 activating transcription factor 5 (A)"	--	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper	Cyclic AMP-dependent transcription factor ATF-5 GN=ATF5 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: cyclic AMP-dependent transcription factor ATF-5 [Erinaceus europaeus]
ENSG00000169139(UBE2V2)	--	38.71995054	1015	38.507852	1100	39.582518	1116	43.16786009	1229	43.60113089	1158	45.0263807	1093	0.943631564	0.244835724	normal	0.979513715	0.052634643	normal	0.980229755	-0.038282647	normal	0.723148269	0.085643065	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10704|2.47095e-102|ptr:740505|UBE2V2; ubiquitin-conjugating enzyme E2 variant 2; K10704 ubiquitin-conjugating enzyme E2 variant (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 variant 2 GN=UBE2V2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 variant 2 isoform X1 [Bubalus bubalis]
ENSG00000169155(ZBTB43)	--	3.133512096	286	4.956821	378	3.134424	278	3.16669391	295	4.040935864	386	4.527683658	408	0.967574294	0.013794578	normal	0.968483521	0.008753401	normal	0.327630093	0.542741331	normal	0.605492951	0.188649331	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10514|0|ptr:473063|ZBTB43; zinc finger and BTB domain containing 43; K10514 zinc finger and BTB domain-containing protein 43 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 43 GN=ZBTB43 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 43 [Galeopterus variegatus]
ENSG00000169169(CPT1C)	--	3.73978524	75	1.94473483	71	2.714199165	74	1.1931265	51	2.43182627	73	1.35501279	43	0.864228316	-0.5729	normal	0.97309983	0.018267168	normal	0.644533304	-0.770575335	normal	0.432449872	-0.419010811	normal	--	--	"Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	K08765|0|pon:100172407|CPT1C; carnitine palmitoyltransferase 1C (EC:2.3.1.21); K08765 carnitine O-palmitoyltransferase 1 [EC:2.3.1.21] (A)	Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; AMPK signaling pathway (ko04152);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	Choline/Carnitine o-acyltransferase	"Carnitine O-palmitoyltransferase 1, brain isoform GN=CPT1C OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: carnitine O-palmitoyltransferase 1, brain isoform isoform X2 [Galeopterus variegatus]"
ENSG00000169174(PCSK9)	--	2.545889076	158	3.217021309	199	3.592688879	219	6.511719	393	9.086500231	563	25.23067298	1642	6.10E-08	1.275648594	up	9.14E-12	1.471997266	up	0	2.889592087	up	0.189783821	2.156548583	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K13050|0|hsa:255738|PCSK9, FH3, HCHOLA3, LDLCQ1, NARC-1, NARC1, PC9; proprotein convertase subtilisin/kexin type 9; K13050 proprotein convertase subtilisin/kexin type 9 [EC:3.4.21.-] (A)"	--	--	--	Subtilase family;; Peptidase inhibitor I9	Proprotein convertase subtilisin/kexin type 9 (Precursor) GN=PCSK9 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proprotein convertase subtilisin/kexin type 9 [Trichechus manatus latirostris]
ENSG00000169180(XPO6)	--	34.99008181	2731	34.069747	2747	42.17484206	3063	39.350706	3192	36.116454	2819	39.09669367	3055	0.978942101	0.194097996	normal	0.989316808	0.015891374	normal	0.990339508	-0.012058468	normal	0.792609278	0.064890417	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Exportin 1-like protein;; Importin-beta N-terminal domain	Exportin-6 GN=XPO6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exportin-6 [Sus scrofa]
ENSG00000169184(MN1)	--	0.504006	69	0.431754	60	0.377561	53	1.82861	251	2.00802	277	0.989933	138	7.54E-12	1.809647678	up	1.11E-16	2.157689416	up	0.000107092	1.34760732	up	0.000502808	1.848720102	up	--	--	--	--	--	--	--	--	Probable tumor suppressor protein MN1 GN=MN1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: probable tumor suppressor protein MN1 [Pteropus alecto]
ENSG00000169188(APEX2)	--	15.62385048	965	13.074577	821	15.783571	982	15.377782	945	14.96693348	914	13.496281	835	0.977579222	-0.06094881	normal	0.969427627	0.133152853	normal	0.94058137	-0.241833917	normal	0.825685166	-0.060434293	normal	[L]	"Replication, recombination and repair"	Molecular Function: zinc ion binding (GO:0008270);; 	K10772|0|pon:100434759|APEX2; APEX nuclease (apurinic/apyrimidinic endonuclease) 2; K10772 AP endonuclease 2 [EC:4.2.99.18] (A)	Base excision repair (ko03410)	[L]	"Replication, recombination and repair"	Endonuclease/Exonuclease/phosphatase family;; GRF zinc finger;; Endonuclease-reverse transcriptase	DNA-(apurinic or apyrimidinic site) lyase 2 GN=APEX2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA-(apurinic or apyrimidinic site) lyase 2 isoform 1 [Ceratotherium simum simum]
ENSG00000169189(NSMCE1)	--	30.42146881	523	26.40245505	452	30.12795101	521	29.79953753	520	33.08061341	576	31.21285992	540	0.971489895	-0.039016636	normal	0.863910464	0.327347221	normal	0.97161977	0.043261245	normal	0.704388365	0.108182155	normal	--	--	Biological Process: DNA repair (GO:0006281);; Cellular Component: Smc5-Smc6 complex (GO:0030915);; 	--	--	[B]	Chromatin structure and dynamics	Nse1 non-SMC component of SMC5-6 complex;; RING-like domain	Non-structural maintenance of chromosomes element 1 homolog GN=NSMCE1 OS=Homo sapiens (Human) PE=1 SV=5	B	Chromatin structure and dynamics	PREDICTED: non-structural maintenance of chromosomes element 1 homolog [Lipotes vexillifer]
ENSG00000169193(CCDC126)	--	2.849755937	94	2.918808032	104	2.640513774	85	2.315739548	80	3.838251857	114	1.75367938	60	0.956221044	-0.258899904	normal	0.96566181	0.109502552	normal	0.887346633	-0.500147472	normal	0.759741595	-0.177909147	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4525)	Coiled-coil domain-containing protein 126 (Precursor) GN=CCDC126 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 126 [Orcinus orca] 
ENSG00000169194(IL13)	--	0	0	0	0	0	0	0	0	0.0999825	1	0.0503261	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05435|9.95392e-89|hsa:3596|IL13, IL-13, P600; interleukin 13; K05435 interleukin 13 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Fc epsilon RI signaling pathway (ko04664);; Measles (ko05162);; Asthma (ko05310);; Inflammatory bowel disease (IBD) (ko05321)	--	--	Interleukin-13	Interleukin-13 (Precursor) GN=IL13 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-13 [Orcinus orca] 
ENSG00000169203(NPIPB12)	--	2.068653019	43	1.821822856	37	2.646084974	55	1.276330644	27	1.532220989	33	2.519208783	54	0.920180761	-0.671650715	normal	0.979948891	-0.178745165	normal	0.977619307	-0.033825006	normal	0.72414429	-0.26241418	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Putative NPIP-like protein LOC613037 OS=Homo sapiens (Human) PE=5 SV=4	S	Function unknown	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000169213(RAB3B)	--	5.613059	1381	3.6864	902	6.186973184	1500	11.41840673	2809	10.25279468	2515	10.03772659	2475	3.65E-07	0.992721289	normal	1.67E-15	1.456407325	up	0.00343015	0.713608763	normal	2.27E-09	1.022745494	up	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K06108|6.3362e-163|hsa:5865|RAB3B; RAB3B, member RAS oncogene family; K06108 Ras-related protein Rab-3B (A)"	Tight junction (ko04530)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Signal recognition particle receptor beta subunit;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-3B GN=RAB3B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-3B isoform 1 [Ceratotherium simum simum] 
ENSG00000169217(CD2BP2)	--	31.18812897	1962	30.52518695	2088	27.50427238	1875	33.82224633	2248	36.45596674	2402	32.58604069	2085	0.978332612	0.16536369	normal	0.976829436	0.180565873	normal	0.980117036	0.144754583	normal	0.397189596	0.16335927	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13099|0|hsa:10421|CD2BP2, FWP010, LIN1, PPP1R59, Snu40, U5-52K; CD2 (cytoplasmic tail) binding protein 2; K13099 CD2 antigen cytoplasmic tail-binding protein 2 (A)"	--	[R]	General function prediction only	GYF domain	CD2 antigen cytoplasmic tail-binding protein 2 GN=CD2BP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: CD2 antigen cytoplasmic tail-binding protein 2 isoform 2 [Dasypus novemcinctus]
ENSG00000169218(RSPO1)	--	0.019884643	1	0	0	0	0	0	0	0.073283747	3	0.039318938	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thrombospondin type 1 domain	R-spondin-1 (Precursor) GN=RSPO1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: R-spondin-1 [Tupaia chinensis]
ENSG00000169220(RGS14)	--	1.38519586	66	1.0099876	49	1.1635556	57	0.72372216	34	0.848872639	40	0.72163201	35	0.397604536	-0.956181354	normal	0.969016636	-0.303811487	normal	0.854180125	-0.688370138	normal	0.204732315	-0.679058943	normal	--	--	Molecular Function: receptor signaling protein activity (GO:0005057);; Biological Process: signal transduction (GO:0007165);; Molecular Function: GTPase regulator activity (GO:0030695);; 	K17706|0|hsa:10636|RGS14; regulator of G-protein signaling 14; K17706 regulator of G-protein signaling 14 (A)	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Raf-like Ras-binding domain;; Regulator of G protein signaling domain;; GoLoco motif	Regulator of G-protein signaling 14 GN=RGS14 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 14 [Physeter catodon]
ENSG00000169221(TBC1D10B)	--	20.32206867	1333	18.95163208	1282	22.12904895	1506	24.29359443	1592	20.81032772	1354	20.97662283	1387	0.957999386	0.225093652	normal	0.981158803	0.0573391	normal	0.977903294	-0.126912585	normal	0.845497176	0.050973172	normal	[R]	General function prediction only	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	TBC1 domain family member 10B GN=TBC1D10B OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TBC1 domain family member 10B [Equus przewalskii]
ENSG00000169223(LMAN2)	--	96.226889	2855	94.13012934	2856	95.957447	2835	107.8896387	3294	107.9357379	3198	113.8431014	3451	0.98214103	0.175429602	normal	0.98519411	0.14167648	normal	0.957042384	0.275241019	normal	0.282751224	0.1973529	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K10082|0|ggo:101150820|LMAN2; vesicular integral-membrane protein VIP36; K10082 lectin, mannose-binding 2 (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Legume-like lectin family	Vesicular integral-membrane protein VIP36 (Precursor) GN=LMAN2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicular integral-membrane protein VIP36 [Oryctolagus cuniculus]
ENSG00000169228(RAB24)	--	20.16776821	471	18.96027534	469	19.1710061	473	16.0320072	371	14.83637319	335	22.98628472	547	0.796176084	-0.373762564	normal	0.433288276	-0.504917192	normal	0.947974877	0.200811693	normal	0.60784187	-0.193407976	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07912|6.96727e-139|ptr:471755|RAB24; RAB24, member RAS oncogene family; K07912 Ras-related protein Rab-24 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Ras-related protein Rab-24 GN=RAB24 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-24 [Galeopterus variegatus]
ENSG00000169230(PRELID1)	--	90.22996	1963	95.165819	2099	94.225623	2108	98.16955	2170	92.74557	2014	95.017399	2094	0.983455537	0.113717932	normal	0.985035088	-0.081005453	normal	0.987254133	-0.017891988	normal	0.992544847	0.003764055	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PRELI-like family	"PRELI domain-containing protein 1, mitochondrial (Precursor) GN=PRELID1 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: PRELI domain-containing protein 1, mitochondrial isoform X1 [Equus przewalskii] "
ENSG00000169231(THBS3)	--	5.309429783	369	4.458317239	313	4.071099097	284	3.352678994	232	3.679912466	252	4.398050289	305	0.04350276	-0.696634581	normal	0.873301504	-0.332371843	normal	0.963848135	0.094143045	normal	0.234968302	-0.312646067	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: cell adhesion (GO:0007155);; 	K04659|0|ptr:457359|THBS3; thrombospondin 3; K04659 thrombospondin 2/3/4/5 (A)	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Malaria (ko05144)	--	--	Thrombospondin C-terminal region;; Thrombospondin type 3 repeat;; Cartilage oligomeric matrix protein;; Calcium-binding EGF domain;; Complement Clr-like EGF-like	Thrombospondin-3 (Precursor) GN=THBS3 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: thrombospondin-3 isoform 1 [Ceratotherium simum simum]
ENSG00000169239(CA5B)	--	8.70438281	583	7.42503462	714	8.64428937	686	6.65011877	726	9.18976602	666	12.51057075	863	0.906304469	0.284967338	normal	0.967783385	-0.121561792	normal	0.87130763	0.3222259	normal	0.503145036	0.164789865	normal	[P]	Inorganic ion transport and metabolism	--	"K01672|0|ptr:737324|CA5B; carbonic anhydrase VB, mitochondrial; K01672 carbonic anhydrase [EC:4.2.1.1] (A)"	Nitrogen metabolism (ko00910)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	"Carbonic anhydrase 5B, mitochondrial (Precursor) GN=CA5B OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: carbonic anhydrase 5B, mitochondrial [Felis catus] "
ENSG00000169241(SLC50A1)	--	33.399721	550	24.91343722	402	31.4942808	516	24.161974	394	25.967715	425	27.6921325	456	0.366317241	-0.51037499	normal	0.967641814	0.058626277	normal	0.951824411	-0.18604825	normal	0.354603077	-0.223883826	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K15382|1.60508e-139|pps:100988694|SLC50A1; solute carrier family 50 (sugar efflux transporter), member 1; K15382 solute carrier family 50 (sugar transporter) (A)"	--	[R]	General function prediction only	Sugar efflux transporter for intercellular exchange	Sugar transporter SWEET1 GN=SLC50A1 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sugar transporter SWEET1 isoform X3 [Pteropus alecto] 
ENSG00000169242(EFNA1)	--	8.88987	333	13.37687	490	10.2002	352	20.55434	766	29.84592	1071	41.52064	1553	2.12E-08	1.16734118	up	7.29E-08	1.104316294	up	0	2.128360076	up	0.008066616	1.509171552	up	--	--	Cellular Component: membrane (GO:0016020);; 	K05462|9.43982e-146|ptr:740136|EFNA1; ephrin-A1; K05462 ephrin-A (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Ephrin	"Ephrin-A1, secreted form (Precursor) GN=EFNA1 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: ephrin-A1 isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000169245(CXCL10)	--	0	0	0.0638248	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K12671|1.72908e-62|nle:100599244|CXCL10; chemokine (C-X-C motif) ligand 10; K12671 C-X-C motif chemokine 10 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; TNF signaling pathway (ko04668);; Influenza A (ko05164)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	CXCL10(1-73) (Precursor) GN=CXCL10 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	CXCL10 [Sus scrofa]
ENSG00000169246(NPIPB3)	--	9.349500499	126	8.914115598	132	11.962893	178	11.47754833	145	6.13345322	110	11.81279662	178	0.959130802	0.16986499	normal	0.938301207	-0.280929755	normal	0.967178569	-0.008221592	normal	0.967825638	-0.030029915	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B5 GN=NPIPB5 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	--
ENSG00000169247(SH3TC2)	--	0.10779392	10	0.09503978	9	0.26265903	24	0.34205567	29	0.295185148	21	0.357885647	29	0.644729764	1.376328435	normal	0.932024919	1.079470753	normal	0.983325141	0.250357856	normal	0.223420472	0.858006436	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"Tetratricopeptide repeat;; TPR repeat;; Variant SH3 domain;; Soluble NSF attachment protein, SNAP;; SH3 domain;; Variant SH3 domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	SH3 domain and tetratricopeptide repeat-containing protein 2 GN=SH3TC2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SH3 domain and tetratricopeptide repeat-containing protein 2 [Ceratotherium simum simum]
ENSG00000169249(ZRSR2)	--	3.239153	119	4.093774051	149	2.91433387	113	4.731757831	164	4.032133247	152	4.598004697	175	0.842605856	0.427186675	normal	0.966545978	0.007259487	normal	0.447406947	0.616065027	normal	0.356553136	0.344554137	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[A]	RNA processing and modification	"Zinc finger C-x8-C-x5-C-x3-H type (and similar);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 GN=ZRSR2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 [Oryctolagus cuniculus]
ENSG00000169251(NMD3)	--	25.8586692	1164	25.50365	1140	27.2826259	1267	26.81740606	1182	24.863063	1081	22.16307183	992	0.981347066	-0.008681914	normal	0.976662854	-0.097960387	normal	0.820358561	-0.360807968	normal	0.454242137	-0.155215941	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K07562|0|hsa:51068|NMD3; NMD3 ribosome export adaptor; K07562 nonsense-mediated mRNA decay protein 3 (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	NMD3 family	60S ribosomal export protein NMD3 GN=NMD3 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal export protein NMD3 isoform X1 [Oryctolagus cuniculus] 
ENSG00000169252(ADRB2)	--	0.413717	23	0.230245	13	0.385951	21	8.99E-05	0	0.783567	43	0.00100196	0	0.000501559	-4.01176036	down	0.063978787	1.596982709	normal	0.001939059	-3.899780498	down	0.892100274	-0.425924412	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04142|0|pps:100983950|ADRB2; adrenoceptor beta 2, surface; K04142 adrenergic receptor beta-2 (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Endocytosis (ko04144);; Adrenergic signaling in cardiomyocytes (ko04261);; Salivary secretion (ko04970)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Beta-2 adrenergic receptor GN=ADRB2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: beta-2 adrenergic receptor [Oryctolagus cuniculus]
ENSG00000169255(B3GALNT1)	--	0.525612492	13	0.414245613	22	0.2035255	4	0.072765114	2	0.210547474	5	0.0644209	2	--	--	--	0.424517732	-1.87042986	normal	--	--	--	--	--	--	--	--	"Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K00719|0|hsa:8706|B3GALNT1, B3GALT3, GLCT3, GLOB, Gb4Cer, P, P1, beta3Gal-T3, galT3; beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) (EC:2.4.1.79); K00719 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase [EC:2.4.1.79] (A)"	Glycosphingolipid biosynthesis - globo series (ko00603)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase;; Fringe-like	"UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 GN=B3GALNT1 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1 [Orycteropus afer afer]"
ENSG00000169258(GPRIN1)	--	5.40016	520	4.44132	434	4.72238	464	4.77429	461	5.64984	542	3.08877	298	0.946372443	-0.203936654	normal	0.893873532	0.298239678	normal	0.070351268	-0.644461098	normal	0.755021989	-0.146394464	normal	--	--	--	--	--	--	--	G protein-regulated inducer of neurite outgrowth C-terminus	G protein-regulated inducer of neurite outgrowth 1 GN=GPRIN1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: G protein-regulated inducer of neurite outgrowth 1 [Lipotes vexillifer]
ENSG00000169282(KCNAB1)	--	0.202922173	10	0.170081168	9	0.36086505	18	0.245224727	13	0.426901237	22	0.284408202	15	--	--	--	0.909292967	1.1421424	normal	--	--	--	--	--	--	[C]	Energy production and conversion	--	"K04882|0|pon:100462552|KCNAB1; potassium voltage-gated channel, shaker-related subfamily, beta member 1; K04882 potassium voltage-gated channel Shaker-related subfamily A, beta member 1 (A)"	--	[C]	Energy production and conversion	Aldo/keto reductase family	Voltage-gated potassium channel subunit beta-1 GN=KCNAB1 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: voltage-gated potassium channel subunit beta-1 isoform X1 [Orycteropus afer afer]
ENSG00000169288(MRPL1)	--	14.62130901	316	14.21559325	306	17.32758095	370	16.84026567	361	16.668688	364	12.76390487	277	0.955192803	0.16051149	normal	0.935643296	0.227946298	normal	0.716189122	-0.423921004	normal	0.991931398	-0.007089957	normal	--	--	--	"K02863|0|hsa:65008|MRPL1, BM022, L1MT, MRP-L1; mitochondrial ribosomal protein L1; K02863 large subunit ribosomal protein L1 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L1;; Ribosomal protein L1p/L10e family	"39S ribosomal protein L1, mitochondrial (Precursor) GN=MRPL1 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L1, mitochondrial isoform X1 [Pantholops hodgsonii]"
ENSG00000169291(SHE)	--	0	0	0	0	0	0	0.036799124	4	0.044807952	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SH2 domain	SH2 domain-containing adapter protein E GN=SHE OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SH2 domain-containing adapter protein E [Galeopterus variegatus]
ENSG00000169297(NR0B1)	--	19.16747	562	27.037293	860	21.28721	658	7.727858	240	5.616117	177	11.870869	370	6.32E-09	-1.252960078	down	0	-2.292164972	down	0.000590763	-0.83625467	normal	0.000169824	-1.422288778	down	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; "	"K08562|0|hsa:190|NR0B1, AHC, AHCH, AHX, DAX-1, DAX1, DSS, GTD, HHG, NROB1, SRXY2; nuclear receptor subfamily 0, group B, member 1; K08562 nuclear receptor subfamily 0 group B member 1 (A)"	--	[T]	Signal transduction mechanisms	Nuclear receptor repeat;; Ligand-binding domain of nuclear hormone receptor	Nuclear receptor subfamily 0 group B member 1 GN=NR0B1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor subfamily 0 group B member 1 [Oryctolagus cuniculus]
ENSG00000169299(PGM2)	--	9.294822	446	7.914138084	410	9.54523	455	7.907812	393	5.954065507	309	7.759379909	361	0.942309728	-0.212565888	normal	0.697506099	-0.427620159	normal	0.849503123	-0.340884209	normal	0.161961662	-0.323954298	normal	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: intramolecular transferase activity, phosphotransferases (GO:0016868);; Biological Process: organic substance metabolic process (GO:0071704);; "	K15779|0|hsa:55276|PGM2; phosphoglucomutase 2 (EC:5.4.2.2 5.4.2.7); K15779 phosphoglucomutase / phosphopentomutase [EC:5.4.2.2 5.4.2.7] (A)	Glycolysis / Gluconeogenesis (ko00010);; Pentose phosphate pathway (ko00030);; Galactose metabolism (ko00052);; Purine metabolism (ko00230);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	"Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II;; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III;; Phosphoglucomutase/phosphomannomutase, C-terminal domain"	Phosphoglucomutase-2 GN=PGM2 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: phosphoglucomutase-2 [Orcinus orca]
ENSG00000169302(STK32A)	--	0.096520577	9	0.089072058	8	0.088972014	7	0.311562841	28	0.5483261	49	0.2445923	23	0.595698793	1.459324087	normal	9.97E-05	2.389368173	up	0.710780513	1.518587237	normal	0.005957456	2.037292382	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08793|0|mcc:708524|STK32A, STK32B; serine/threonine kinase 32A; K08793 serine/threonine kinase 32 [EC:2.7.11.1] (A)"	--	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase 32A GN=STK32A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 32A isoform X1 [Loxodonta africana]
ENSG00000169306(IL1RAPL1)	--	0	0	0.0152688	1	0	0	0.0151746	1	0.089002458	5	0.076023971	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K05170|0|ptr:450116|IL1RAPL1; interleukin 1 receptor accessory protein-like 1; K05170 interleukin 1 receptor accessory protein-like (A)	--	--	--	TIR domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Interleukin-1 receptor accessory protein-like 1 (Precursor) GN=IL1RAPL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor accessory protein-like 1 [Ochotona princeps]
ENSG00000169330(KIAA1024)	--	0.578511	51	0.627119594	58	0.579567962	50	0.4235536	45	0.701981613	73	0.4063818	43	0.975302908	-0.204829922	normal	0.9568485	0.303353885	normal	0.974819723	-0.218741845	normal	1	-0.00317524	normal	--	--	--	--	--	--	--	Uncharacterised protein family (UPF0258)	UPF0258 protein KIAA1024 GN=KIAA1024 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: UPF0258 protein KIAA1024 homolog [Ceratotherium simum simum]
ENSG00000169359(SLC33A1)	--	19.7046292	824	20.608125	905	21.22727217	840	21.2715722	967	20.6714109	867	27.94835515	1239	0.956335855	0.199695304	normal	0.974841197	-0.083170347	normal	0.157392856	0.551600844	normal	0.39719767	0.23788178	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Molecular Function: acetyl-CoA transporter activity (GO:0008521);; Cellular Component: integral component of membrane (GO:0016021);; 	"K03372|0|hsa:9197|SLC33A1, ACATN, AT-1, AT1, CCHLND, SPG42; solute carrier family 33 (acetyl-CoA transporter), member 1; K03372 MFS transporter, PAT family, solute carrier family 33 (acetyl-CoA transportor), member 1 [EC:2.3.1.-] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	[P]	Inorganic ion transport and metabolism	Acetyl-coenzyme A transporter 1	Acetyl-coenzyme A transporter 1 GN=SLC33A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: acetyl-coenzyme A transporter 1 isoform X1 [Mustela putorius furo] 
ENSG00000169371(SNUPN)	--	17.49737376	530	20.11120723	601	20.00997332	554	15.87666274	442	14.07175452	400	16.68584233	466	0.898474776	-0.291850242	normal	0.103091783	-0.606905839	normal	0.923492236	-0.257081285	normal	0.053494348	-0.386527243	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13151|0|hsa:10073|SNUPN, KPNBL, RNUT1, Snurportin1; snurportin 1; K13151 snurportin-1 (A)"	RNA transport (ko03013)	[A]	RNA processing and modification	Snurportin1	Snurportin-1 GN=SNUPN OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: snurportin-1 isoform X1 [Equus przewalskii]
ENSG00000169372(CRADD)	--	6.625168189	117	7.522280863	140	6.53024961	122	7.084210642	134	9.230121	159	9.162125883	172	0.961054011	0.1628924	normal	0.957452598	0.160545277	normal	0.759142669	0.482178706	normal	0.50447543	0.274486174	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; Biological Process: regulation of apoptotic process (GO:0042981);; 	"K02832|1.77302e-130|hsa:8738|CRADD, MRT34, RAIDD; CASP2 and RIPK1 domain containing adaptor with death domain; K02832 CASP2 and RIPK1 domain containing adaptor with death domain (A)"	--	--	--	Caspase recruitment domain;; Death domain	Death domain-containing protein CRADD GN=CRADD OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: death domain-containing protein CRADD [Galeopterus variegatus] 
ENSG00000169375(SIN3A)	--	29.50548735	2679	23.61054773	2488	30.49153152	2559	19.11765952	2095	21.37829436	2084	17.06356177	1873	0.81202305	-0.385325966	normal	0.947737414	-0.276873605	normal	0.551672749	-0.458202849	normal	0.015367627	-0.37380733	normal	[B]	Chromatin structure and dynamics	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K11644|0|hsa:25942|SIN3A; SIN3 transcription regulator family member A; K11644 paired amphipathic helix protein Sin3a (A)	Thyroid hormone signaling pathway (ko04919);; Huntington's disease (ko05016);; Transcriptional misregulation in cancer (ko05202)	[B]	Chromatin structure and dynamics	Paired amphipathic helix repeat;; Sin3 family co-repressor	Paired amphipathic helix protein Sin3a OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: paired amphipathic helix protein Sin3a [Dasypus novemcinctus]
ENSG00000169379(ARL13B)	--	8.526162196	475	9.63577515	539	9.018504628	476	9.100316005	516	8.563556167	490	7.264837928	405	0.968002718	0.088337105	normal	0.95810981	-0.158463553	normal	0.931390193	-0.240501786	normal	0.735704067	-0.100607713	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07962|0|hsa:200894|ARL13B, ARL2L1, JBTS8; ADP-ribosylation factor-like 13B; K07962 ADP-ribosylation factor-like protein 13B (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Signal recognition particle receptor beta subunit	ADP-ribosylation factor-like protein 13B GN=ARL13B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 13B isoform X1 [Vicugna pacos]
ENSG00000169398(PTK2)	--	43.26021612	3195	44.5922084	3027	41.9610951	3134	45.72811178	3619	44.6476839	3444	42.14868102	3042	0.986074073	0.148875617	normal	0.983800938	0.164692731	normal	0.989913466	-0.051251365	normal	0.695199456	0.089438757	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein tyrosine kinase activity (GO:0004713);; Molecular Function: signal transducer activity (GO:0004871);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: focal adhesion (GO:0005925);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal complex assembly (GO:0007172);; 	K05725|0|nle:100589794|PTK2; PTK2 protein tyrosine kinase 2; K05725 focal adhesion kinase 1 [EC:2.7.10.2] (A)	ErbB signaling pathway (ko04012);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Bacterial invasion of epithelial cells (ko05100);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Proteoglycans in cancer (ko05205);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Focal adhesion targeting region;; Protein kinase domain;; FERM central domain	Focal adhesion kinase 1 GN=PTK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: focal adhesion kinase 1 isoform X5 [Equus caballus]
ENSG00000169402(RSPH10B2)	--	0	0	0	0	0.383904	2	0.033447811	2	0	0	0.016835383	1	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat	Radial spoke head 10 homolog B2 GN=RSPH10B2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: radial spoke head 10 homolog B2 [Tupaia chinensis]
ENSG00000169403(PTAFR)	--	0.382737873	18	0.17091382	14	0.21775313	17	0.381718528	27	0.34176494	27	0.380779784	31	0.976660628	0.517847242	normal	0.937424095	0.858358575	normal	0.932493748	0.80474194	normal	0.268268498	0.774053683	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04279|0|nle:100590550|PTAFR; platelet-activating factor receptor; K04279 platelet-activating factor receptor (A)	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Staphylococcus aureus infection (ko05150)	--	--	7 transmembrane receptor (rhodopsin family)	Platelet-activating factor receptor GN=PTAFR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: platelet-activating factor receptor [Orycteropus afer afer]
ENSG00000169410(PTPN9)	--	19.793133	1597	19.78413138	1545	18.36825526	1507	23.09200608	1876	25.09301929	1953	23.28452472	1834	0.968475649	0.20128444	normal	0.908509352	0.316382565	normal	0.938308958	0.274772454	normal	0.120712638	0.263352523	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18038|0|hsa:5780|PTPN9, MEG2, PTPMEG2; protein tyrosine phosphatase, non-receptor type 9 (EC:3.1.3.48); K18038 tyrosine-protein phosphatase non-receptor type 9 [EC:3.1.3.48] (A)"	--	--	--	"Protein-tyrosine phosphatase;; CRAL/TRIO domain;; Divergent CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain"	Tyrosine-protein phosphatase non-receptor type 9 GN=PTPN9 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: tyrosine-protein phosphatase non-receptor type 9 [Orycteropus afer afer]
ENSG00000169418(NPR1)	--	0.634870512	52	0.7141243	61	1.040382029	88	0.997745743	84	1.04239927	87	2.281041166	194	0.769123956	0.645904661	normal	0.893077491	0.480753597	normal	0.000360545	1.118912296	up	0.360022697	0.842877379	normal	[T]	Signal transduction mechanisms	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12323|0|hsa:4881|NPR1, ANPRA, ANPa, GUC2A, GUCY2A, NPRA; natriuretic peptide receptor 1 (EC:4.6.1.2); K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Vascular smooth muscle contraction (ko04270);; Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	Adenylate and Guanylate cyclase catalytic domain;; Receptor family ligand binding region;; Protein tyrosine kinase;; Protein kinase domain	Atrial natriuretic peptide receptor 1 (Precursor) GN=NPR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: atrial natriuretic peptide receptor 1, partial [Galeopterus variegatus]"
ENSG00000169427(KCNK9)	--	0.136966327	3	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	"K04919|0|ptr:464416|KCNK9; potassium channel, subfamily K, member 9; K04919 potassium channel subfamily K member 9 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel;; Ion transport protein	Potassium channel subfamily K member 9 GN=KCNK9 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 9 [Odobenus rosmarus divergens]
ENSG00000169429(CXCL8)	--	21.445156	527	26.04239	612	15.52040327	372	80.75069	1978	75.988128	1871	81.29193	1991	0	1.874312215	up	0	1.58841954	up	0	2.407089498	up	1.76E-45	1.928534544	up	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K10030|2.84956e-53|ptr:471205|CXCL8, IL8; chemokine (C-X-C motif) ligand 8; K10030 interleukin 8 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Chagas disease (American trypanosomiasis) (ko05142);; Malaria (ko05144);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Influenza A (ko05164);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Bladder cancer (ko05219);; Rheumatoid arthritis (ko05323)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	IL-8(9-77) (Precursor) GN=CXCL8 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	interleukin-8 precursor [Oryctolagus cuniculus] 
ENSG00000169432(SCN9A)	--	4.5758698	722	4.3530379	539	3.816872201	601	6.0544557	932	4.99278616	800	4.603975026	756	0.851779584	0.336866487	normal	0.214134443	0.54702085	normal	0.869609017	0.322005866	normal	0.035301214	0.396250665	normal	--	--	Cellular Component: voltage-gated sodium channel complex (GO:0001518);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated sodium channel activity (GO:0005248);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04841|0|ptr:459704|SCN9A; sodium channel, voltage-gated, type IX, alpha subunit; K04841 voltage-gated sodium channel type IX alpha (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Domain of unknown function (DUF3451);; Sodium ion transport-associated;; Polycystin cation channel	Sodium channel protein type 9 subunit alpha GN=SCN9A OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel protein type 9 subunit alpha [Tupaia chinensis]
ENSG00000169435(RASSF6)	--	0.532187938	45	0.222565119	24	0.358250059	36	1.756831117	180	2.50104005	214	2.4016221	267	1.12E-10	1.93363276	up	0	3.057789624	up	0	2.831451975	up	1.37E-13	2.634463567	up	--	--	Biological Process: signal transduction (GO:0007165);; 	K09854|0|ggo:101129647|RASSF6; ras association domain-containing protein 6 isoform 1; K09854 Ras association domain-containing protein 6 (A)	Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain	Ras association domain-containing protein 6 GN=RASSF6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras association domain-containing protein 6 [Chrysochloris asiatica]
ENSG00000169436(COL22A1)	--	0.489169103	26	0.646198094	33	0.385728582	19	0.101227095	9	0.612548688	24	0.025044303	4	0.684112758	-1.413676818	normal	0.970812511	-0.456239947	normal	--	--	--	0.174192125	-1.098445078	normal	--	--	--	"K16630|0|hsa:169044|COL22A1; collagen, type XXII, alpha 1; K16630 collagen, type XXII, alpha (A)"	Protein digestion and absorption (ko04974)	[T]	Signal transduction mechanisms	Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; von Willebrand factor type A domain	Collagen alpha-1(XXII) chain (Precursor) GN=COL22A1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(XXII) chain [Mustela putorius furo] 
ENSG00000169439(SDC2)	--	0.565116216	28	0.843356699	37	1.904009016	52	0.555268429	9	1.109642266	9	0.347847458	17	0.505664109	-1.514888848	normal	0.027007717	-1.892707379	normal	0.026527131	-1.53922262	normal	0.001660686	-1.759496357	down	--	--	--	"K16336|2.65888e-111|hsa:6383|SDC2, CD362, HSPG, HSPG1, SYND2; syndecan 2; K16336 syndecan 2 (A)"	Cell adhesion molecules (CAMs) (ko04514);; Malaria (ko05144);; Proteoglycans in cancer (ko05205)	--	--	Syndecan domain	Syndecan-2 (Precursor) GN=SDC2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: syndecan-2 [Odobenus rosmarus divergens]
ENSG00000169446(MMGT1)	--	17.2225	775	17.4692	779	17.0818	747	16.0525	730	14.8121	667	15.1215	683	0.970007839	-0.116893275	normal	0.934629642	-0.244848832	normal	0.966692002	-0.137223467	normal	0.458762106	-0.167168618	normal	--	--	--	--	--	[S]	Function unknown	Membrane magnesium transporter	Membrane magnesium transporter 1 (Precursor) GN=MMGT1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: membrane magnesium transporter 1 [Mustela putorius furo] 
ENSG00000169490(TM2D2)	--	25.61141601	921	25.99114538	956	25.08176763	986	35.64052626	1297	28.60136129	1082	30.35942389	1134	0.491250333	0.46242033	normal	0.968183648	0.156957923	normal	0.961408418	0.193193141	normal	0.121233733	0.273590575	normal	--	--	--	--	--	[R]	General function prediction only	TM2 domain	TM2 domain-containing protein 2 (Precursor) GN=TM2D2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: TM2 domain-containing protein 2 [Ceratotherium simum simum]
ENSG00000169495(HTRA4)	--	0.0593452	2	0	0	0	0	0	0	0	0	0.0294757	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	K08786|0|hsa:203100|HTRA4; HtrA serine peptidase 4; K08786 HtrA serine peptidase 4 [EC:3.4.21.-] (A)	--	--	--	Trypsin-like peptidase domain;; Trypsin;; PDZ domain;; PDZ domain (Also known as DHR or GLGF);; Kazal-type serine protease inhibitor domain;; Peptidase S46;; Kazal-type serine protease inhibitor domain	Serine protease HTRA4 (Precursor) GN=HTRA4 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: serine protease HTR4-like [Elephantulus edwardii]
ENSG00000169499(PLEKHA2)	--	9.707912301	863	9.763373308	934	11.22456752	1077	12.29897711	1122	8.091313	670	8.017852408	751	0.83994713	0.347264437	normal	0.36506772	-0.499727916	normal	0.235031465	-0.527532866	normal	0.641815909	-0.198889804	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: phospholipid binding (GO:0005543);; Cellular Component: cell cortex (GO:0005938);; Biological Process: cortical protein anchoring (GO:0032065);; 	--	--	--	--	PH domain;; Pleckstrin homology domain;; Pleckstrin homology domain;; Pleckstrin homology domain;; Meiotic cell cortex C-terminal pleckstrin homology	Pleckstrin homology domain-containing family A member 2 GN=PLEKHA2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family A member 2 [Orcinus orca]
ENSG00000169504(CLIC4)	--	40.223	2560	44.5781	2822	41.2101	2565	48.7169	3132	44.5545	2830	62.162	3960	0.960924067	0.259966893	normal	0.989428166	-0.017333217	normal	0.043591608	0.617954693	normal	0.231945514	0.29958723	normal	--	--	--	K05024|0|ptr:749398|CLIC4; chloride intracellular channel 4; K05024 chloride intracellular channel protein 4 (A)	--	[P]	Inorganic ion transport and metabolism	"Glutathione S-transferase, N-terminal domain"	Chloride intracellular channel protein 4 GN=CLIC4 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: chloride intracellular channel protein 4 [Orycteropus afer afer]
ENSG00000169509(CRCT1)	--	0	0	0	0	0	0	0.138123	1	0	0	0.142007	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000169515(CCDC8)	--	0.0574422	4	0.0693369	5	0.0682252	4	0.042765	3	0.0279624	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17561|0|hsa:83987|CCDC8, 3M3, PPP1R20, p90; coiled-coil domain containing 8; K17561 coiled-coil domain-containing protein 8 (A)"	--	--	--	PNMA	Coiled-coil domain-containing protein 8 GN=CCDC8 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 8-like [Galeopterus variegatus]
ENSG00000169519(METTL15)	--	8.813280982	580	7.941427394	559	7.864991502	547	9.466192039	639	9.058062	610	9.899256833	694	0.968276239	0.108656486	normal	0.967672492	0.104264328	normal	0.852749358	0.334281065	normal	0.428289421	0.183649034	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	MraW methylase family	Probable methyltransferase-like protein 15 GN=METTL15 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: probable methyltransferase-like protein 15 isoform X1 [Ursus maritimus] 
ENSG00000169548(ZNF280A)	--	1.434398	80	0.786506796	45	1.2335563	60	1.627445879	96	1.992983	100	1.283281501	67	0.960288869	0.228197309	normal	0.02618273	1.105051922	normal	0.972740159	0.147390116	normal	0.306858496	0.485493513	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF4195)	Zinc finger protein 280A GN=ZNF280A OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 280A [Galeopterus variegatus]
ENSG00000169551(CT55)	--	0.0463058	1	0.077573535	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S1-like	Cancer/testis antigen 55 GN=CT55 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein CXorf48-like [Tupaia chinensis]
ENSG00000169554(ZEB2)	--	2.404295277	245	2.59068097	242	2.746886083	288	2.277810098	238	3.84159489	292	3.125681538	293	0.964946555	-0.07219306	normal	0.929178303	0.248121499	normal	0.967615075	0.016454747	normal	0.877071809	0.066482813	normal	[R]	General function prediction only	--	K09299|0|pps:100974809|ZEB2; zinc finger E-box binding homeobox 2; K09299 zinc finger homeobox protein 1/2 (A)	MicroRNAs in cancer (ko05206)	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Drought induced 19 protein (Di19), zinc-binding;; Zinc-finger of C2H2 type;; Homeobox domain"	Zinc finger E-box-binding homeobox 2 GN=HRIHFB2411 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger E-box-binding homeobox 2 isoform X1 [Galeopterus variegatus] 
ENSG00000169564(PCBP1)	--	255.015	7039	265.922	7416	257.552	7226	198.61	5474	196.442	5426	182.848	5069	0.875116735	-0.393509615	normal	0.657628839	-0.472065713	normal	0.384523866	-0.519656981	normal	0.003090188	-0.462571267	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K12889|0|umr:103671366|PCBP1; poly(rC) binding protein 1; K12889 poly(rC)-binding protein 1 (A)	Spliceosome (ko03040)	[AR]	RNA processing and modification;; General function prediction only	KH domain;; KH domain;; KH domain;; KH domain	Poly(rC)-binding protein 1 GN=PCBP1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: poly(rC)-binding protein 1 [Bos mutus] 
ENSG00000169567(HINT1)	--	172.0425	2446	192.224719	2801	174.62275	2503	199.0834852	2878	179.053674	2507	201.1713972	2844	0.975548963	0.203691876	normal	0.979205592	-0.181303012	normal	0.980240834	0.175871984	normal	0.790313523	0.06512182	normal	[FGR]	Nucleotide transport and metabolism;; Carbohydrate transport and metabolism;; General function prediction only	--	K02503|9.68699e-88|ptr:462040|HINT1; histidine triad nucleotide binding protein 1; K02503 histidine triad (HIT) family protein (A)	--	[T]	Signal transduction mechanisms	HIT domain;; Scavenger mRNA decapping enzyme C-term binding	Histidine triad nucleotide-binding protein 1 GN=HINT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: histidine triad nucleotide-binding protein 1-like [Chrysochloris asiatica]
ENSG00000169570(DTWD2)	--	3.308105411	182	3.62128265	224	3.055492719	165	3.645626772	238	4.022470104	258	5.107741382	292	0.872005932	0.353574215	normal	0.950048581	0.181304518	normal	0.012334521	0.809559825	normal	0.105936558	0.443731534	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	DTW domain	DTW domain-containing protein 2 GN=DTWD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DTW domain-containing protein 2 [Odobenus rosmarus divergens]
ENSG00000169583(CLIC3)	--	1.47397	20	0.574784	8	1.11153	15	1.45598	20	2.1279	29	0.504874	7	0.989125045	-0.028632677	normal	0.316596534	1.662334362	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K05023|5.4172e-160|hsa:9022|CLIC3; chloride intracellular channel 3; K05023 chloride intracellular channel protein 3 (A)	--	[P]	Inorganic ion transport and metabolism	"Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, N-terminal domain"	Chloride intracellular channel protein 3 GN=CLIC3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: chloride intracellular channel protein 3 [Ceratotherium simum simum]
ENSG00000169592(INO80E)	--	43.720081	807	43.421638	731	46.88031	832	41.187718	748	39.60624	709	40.759898	792	0.967280175	-0.14008554	normal	0.973362301	-0.065374999	normal	0.974587749	-0.079226923	normal	0.705945714	-0.096486217	normal	--	--	--	"K11669|4.13704e-76|hsa:283899|INO80E, CCDC95; INO80 complex subunit E; K11669 INO80 complex subunit E (A)"	--	--	--	--	INO80 complex subunit E GN=INO80E OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: INO80 complex subunit E isoform X3 [Balaenoptera acutorostrata scammoni] 
ENSG00000169594(BNC1)	--	0.014286164	1	0	0	0.028328794	1	0.010456717	1	0.0202106	1	0.03096917	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Zinc-finger of C2H2 type;; C2H2-type zinc finger;; Zinc finger, C2H2 type"	Zinc finger protein basonuclin-1 GN=BNC1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein basonuclin-1 [Equus caballus]
ENSG00000169598(DFFB)	--	1.673666528	95	2.295866897	93	1.823068706	98	2.717109131	113	1.817281702	101	1.785873563	103	0.957875643	0.216280937	normal	0.96773412	0.096125939	normal	0.969908324	0.062557536	normal	0.831072444	0.127040445	normal	--	--	Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: apoptotic DNA fragmentation (GO:0006309);; Biological Process: apoptotic process (GO:0006915);; Molecular Function: hydrolase activity (GO:0016787);; 	"K02311|0|hsa:1677|DFFB, CAD, CPAN, DFF-40, DFF2, DFF40; DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase); K02311 DNA fragmentation factor, 40 kD, beta subunit [EC:3.-.-.-] (A)"	Apoptosis (ko04210)	--	--	DNA fragmentation factor 40 kDa;; CIDE-N domain	DNA fragmentation factor subunit beta GN=DFFB OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	DNA fragmentation factor subunit beta [Tupaia chinensis]
ENSG00000169599(NFU1)	--	24.58019416	497	24.627826	520	26.682695	516	19.22572024	350	20.39292272	395	17.18203935	326	0.301454969	-0.534742043	normal	0.701088973	-0.416690301	normal	0.038959637	-0.668304266	normal	0.005844745	-0.538692921	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: iron ion binding (GO:0005506);; Biological Process: iron-sulfur cluster assembly (GO:0016226);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Scaffold protein Nfu/NifU N terminal;; NifU-like domain	"NFU1 iron-sulfur cluster scaffold homolog, mitochondrial (Precursor) GN=NFU1 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: NFU1 iron-sulfur cluster scaffold homolog, mitochondrial isoform 1 [Orcinus orca]"
ENSG00000169604(ANTXR1)	--	48.12738825	4755	45.46190399	4334	51.484495	5076	52.43068173	5228	51.50930385	5161	64.69670071	6251	0.991697942	0.105948881	normal	0.979556472	0.230451154	normal	0.965376979	0.292024957	normal	0.2574678	0.211871991	normal	--	--	Molecular Function: receptor activity (GO:0004872);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Anthrax receptor extracellular domain;; Anthrax receptor C-terminus region;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Anthrax toxin receptor 1 (Precursor) GN=ANTXR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: anthrax toxin receptor 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000169605(GKN1)	--	0	0	0	0	0	0	0.0831926	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	BRICHOS domain	Gastrokine-1 (Precursor) GN=GKN1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: gastrokine-1 [Chrysochloris asiatica]
ENSG00000169607(CKAP2L)	--	9.03381	854	7.95159	735	9.97334	916	5.23017	494	4.57524	433	5.74897	546	0.000497872	-0.818594885	normal	0.002115851	-0.78267989	normal	0.002473122	-0.753109293	normal	8.70E-07	-0.786712003	normal	--	--	--	K16769|0|hsa:150468|CKAP2L; cytoskeleton associated protein 2-like; K16769 cytoskeleton-associated protein 2 (A)	--	--	--	Cytoskeleton-associated protein 2 C-terminus	Cytoskeleton-associated protein 2-like GN=CKAP2L OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: cytoskeleton-associated protein 2-like [Ceratotherium simum simum]
ENSG00000169609(C15orf40)	--	8.928496339	598	19.17482631	636	8.504639001	582	14.575292	608	9.685938095	641	9.897403	648	0.973690558	-0.006888871	normal	0.973716704	-0.010105033	normal	0.963222825	0.146322737	normal	0.898352323	0.041857766	normal	[S]	Function unknown	--	K09131|8.89814e-82|hsa:123207|C15orf40; chromosome 15 open reading frame 40; K09131 hypothetical protein (A)	--	[S]	Function unknown	"Uncharacterised ACR, YggU family COG1872"	UPF0235 protein C15orf40 GN=C15orf40 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0235 protein C15orf40 homolog [Loxodonta africana]
ENSG00000169612(FAM103A1)	--	29.9776	643	29.6437	640	28.7129	610	29.4526	646	35.0101	748	34.0318	734	0.974208908	-0.024059481	normal	0.950779985	0.203095543	normal	0.926034633	0.258095289	normal	0.53781129	0.147970536	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Cellular Component: mRNA cap binding complex (GO:0005845);; Biological Process: methylation (GO:0032259);; 	"K18708|1.00178e-51|hsa:83640|FAM103A1, C15orf18, HsT19360, RAM; family with sequence similarity 103, member A1; K18708 RNMT-activating mini protein (A)"	--	--	--	"mRNA cap methylation, RNMT-activating mini protein"	RNMT-activating mini protein GN=FAM103A1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RNMT-activating mini protein [Vicugna pacos] 
ENSG00000169621(APLF)-2	--	1.432044322	97	1.132362852	74	1.183836964	80	0.959944658	66	0.78569992	54	0.969466346	67	0.79340614	-0.57523215	normal	0.917570217	-0.464824429	normal	0.960841878	-0.258777814	normal	0.364987332	-0.445944395	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000169627(BOLA2B)	--	7.310834	31	5.018431	18	11.361899	34	5.169986	11	5.0764	16	8.146414	26	0.516930477	-1.404141867	normal	--	--	--	0.976099284	-0.376129208	normal	0.358230248	-0.665068562	normal	[T]	Signal transduction mechanisms	--	--	--	[T]	Signal transduction mechanisms	BolA-like protein	BolA-like protein 2 GN=BOLA2B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: bolA-like protein 2 [Ailuropoda melanoleuca]
ENSG00000169629(RGPD8)	--	1.0597301	116	0.785308519	85	0.801650451	86	0.836384	93	1.026240421	111	0.747767832	82	0.92704722	-0.344545754	normal	0.923646278	0.35801031	normal	0.971541906	-0.075641843	normal	0.979098518	-0.026653275	normal	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:727851|RGPD8, RANBP2L1, RGP8, RanBP2alpha; RANBP2-like and GRIP domain containing 8; K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; GRIP domain;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RANBP2-like and GRIP domain-containing protein 8 GN=RGPD8 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ceratotherium simum simum]
ENSG00000169635(HIC2)	--	2.0607514	268	1.767984491	236	1.606489038	215	1.424070456	186	1.471246648	182	1.550805302	204	0.422822782	-0.553927379	normal	0.827881836	-0.393395544	normal	0.964282353	-0.083456227	normal	0.240621618	-0.351154927	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	Hypermethylated in cancer 2 protein GN=HIC2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: hypermethylated in cancer 2 protein [Equus przewalskii] 
ENSG00000169641(LUZP1)	--	11.02787691	1608	12.7902828	1939	13.56983768	1876	17.27297438	2669	18.36991459	2772	22.09601859	3263	0.004985364	0.699675638	normal	0.419783269	0.493864181	normal	0.000357112	0.789758939	normal	1.44E-05	0.662058031	normal	--	--	--	--	--	--	--	--	Leucine zipper protein 1 GN=LUZP1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: leucine zipper protein 1 [Galeopterus variegatus]
ENSG00000169660(HEXDC)	--	7.590949003	287	8.212614	319	6.859357011	250	6.674588	238	7.984382602	294	9.00196755	326	0.903232449	-0.29915964	normal	0.957704882	-0.138482732	normal	0.825122363	0.372672777	normal	0.974305101	-0.017212904	normal	--	--	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K14459|0|hsa:284004|HEXDC; hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing (EC:3.2.1.52); K14459 hexosaminidase [EC:3.2.1.52] (A)"	Other glycan degradation (ko00511)	--	--	"Glycosyl hydrolase family 20, catalytic domain"	Hexosaminidase D GN=HEXDC OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: hexosaminidase D [Balaenoptera acutorostrata scammoni]
ENSG00000169679(BUB1)	--	25.92968999	1929	22.07397358	1641	24.11819884	1766	16.60986517	1253	14.2526376	1043	11.39284585	858	0.016944956	-0.652648508	normal	0.01297149	-0.674475881	normal	8.14E-08	-1.048410675	down	9.13E-07	-0.780900089	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02178|0|pps:100972278|BUB1; BUB1 mitotic checkpoint serine/threonine kinase; K02178 checkpoint serine/threonine-protein kinase [EC:2.7.11.1] (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Progesterone-mediated oocyte maturation (ko04914)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mad3/BUB1 homology region 1;; Protein kinase domain;; Protein tyrosine kinase	Mitotic checkpoint serine/threonine-protein kinase BUB1 GN=BUB1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: mitotic checkpoint serine/threonine-protein kinase BUB1 [Panthera tigris altaica]
ENSG00000169682(SPNS1)	--	34.4227121	1113	42.41864462	1398	35.17731068	1168	41.02409549	1324	38.28450385	1218	62.89883326	2054	0.956023224	0.219339394	normal	0.957464509	-0.220021555	normal	0.00025953	0.805307945	normal	0.549153652	0.301006457	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; Sugar (and other) transporter;; MFS/sugar transport protein;; Organic Anion Transporter Polypeptide (OATP) family	Protein spinster homolog 1 GN=SPNS1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: spinster homolog 1 isoform X1 [Sus scrofa]
ENSG00000169683(LRRC45)	--	9.853895086	545	8.28631	503	9.3189195	571	11.273589	663	11.94044698	697	8.5136856	476	0.928145731	0.25127732	normal	0.584638682	0.448024834	normal	0.915578218	-0.270036161	normal	0.600651479	0.159620523	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 45 GN=LRRC45 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 45 isoform X1 [Galeopterus variegatus]
ENSG00000169689(CENPX)	--	99.12229	1108	91.24709398	1062	100.28492	1195	106.5774989	1246	94.35127785	1044	79.87828649	909	0.973556941	0.138332971	normal	0.978922898	-0.046022512	normal	0.714683702	-0.402364137	normal	0.704654063	-0.094967585	normal	--	--	--	"K15360|4.06549e-24|hsa:201254|STRA13, CENP-X, CENPX, D9, FAAP10, MHF2; stimulated by retinoic acid 13; K15360 centromere protein X (A)"	Fanconi anemia pathway (ko03460)	--	--	CENP-S associating Centromere protein X	Centromere protein X GN=STRA13 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: centromere protein X [Oryctolagus cuniculus]
ENSG00000169692(AGPAT2)	--	83.18769291	1542	68.11752584	1342	75.95749771	1488	85.27320885	1666	90.16584413	1734	83.736	1615	0.982699107	0.080676028	normal	0.862897687	0.347946899	normal	0.980400487	0.109761094	normal	0.355994337	0.176791642	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	K13509|3.90699e-178|pps:100977572|AGPAT2; 1-acylglycerol-3-phosphate O-acyltransferase 2; K13509 lysophosphatidate acyltransferase [EC:2.3.1.51] (A)	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Acyltransferase	1-acyl-sn-glycerol-3-phosphate acyltransferase beta (Precursor) GN=AGPAT2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta isoform 2 [Ceratotherium simum simum]
ENSG00000169696(ASPSCR1)	--	18.5259806	536	18.36416697	521	16.8087083	527	15.91189621	467	17.85268962	496	16.27623107	510	0.937154119	-0.228938935	normal	0.967282004	-0.092095793	normal	0.970841222	-0.055435439	normal	0.644620054	-0.125723427	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15627|2.14264e-170|hsa:79058|ASPSCR1, ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9; alveolar soft part sarcoma chromosome region, candidate 1; K15627 tether containing UBX domain for GLUT4 (A)"	Transcriptional misregulation in cancer (ko05202)	[O]	"Posttranslational modification, protein turnover, chaperones"	GLUT4 regulating protein TUG;; UBX domain	Tether containing UBX domain for GLUT4 GN=ASPSCR1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tether containing UBX domain for GLUT4 [Odobenus rosmarus divergens]
ENSG00000169710(FASN)	--	106.3416515	16964	117.0393956	18923	114.4038719	18549	58.42525559	9428	68.5961744	10768	95.117617	14799	2.90E-05	-0.878176647	normal	0.000227829	-0.834727401	normal	0.973941678	-0.334102597	normal	0.001075162	-0.657210922	normal	--	--	"Biological Process: biosynthetic process (GO:0009058);; Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00665|0|hsa:2194|FASN, FAS, OA-519, SDR27X1; fatty acid synthase (EC:2.3.1.85 2.3.1.38 2.3.1.39 2.3.1.41 3.1.2.14 4.2.1.59 1.1.1.100 1.3.1.39); K00665 fatty acid synthase, animal type [EC:2.3.1.85] (A)"	Fatty acid biosynthesis (ko00061);; Fatty acid metabolism (ko01212);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910)	[I]	Lipid transport and metabolism	"Acyl transferase domain;; Beta-ketoacyl synthase, N-terminal domain;; Thioesterase domain;; KR domain;; short chain dehydrogenase;; Beta-ketoacyl synthase, C-terminal domain;; Polyketide synthase dehydratase;; Zinc-binding dehydrogenase;; Zinc-binding dehydrogenase;; Phosphopantetheine attachment site;; Methyltransferase domain;; Methyltransferase domain"	Oleoyl-[acyl-carrier-protein] hydrolase GN=FASN OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: fatty acid synthase [Ceratotherium simum simum]
ENSG00000169714(CNBP)	--	117.9920283	3188	121.9615341	3341	120.6890525	3273	138.5571581	3756	136.0746887	3658	114.1119043	3074	0.979365877	0.205621797	normal	0.988651464	0.109301242	normal	0.988582762	-0.098740794	normal	0.74863308	0.07584021	normal	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	--	"K09250|9.35402e-113|hsa:7555|CNBP, CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9; CCHC-type zinc finger, nucleic acid binding protein; K09250 cellular nucleic acid-binding protein (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Zinc knuckle;; Zinc knuckle;; GAG-polyprotein viral zinc-finger;; Zinc knuckle	Cellular nucleic acid-binding protein GN=CNBP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cellular nucleic acid-binding protein-like isoform X1 [Myotis brandtii]
ENSG00000169715(MT1E)	--	0	0	0	0	0.950695163	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Metallothionein	--	S	Function unknown	--
ENSG00000169718(DUS1L)	--	39.49407694	1127	37.64225442	1144	41.44793052	1258	55.247017	1663	55.20217166	1580	54.23118	1570	0.218265872	0.529870389	normal	0.596065435	0.44390966	normal	0.902952164	0.311005881	normal	0.005134321	0.42648731	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: tRNA processing (GO:0008033);; Molecular Function: tRNA dihydrouridine synthase activity (GO:0017150);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K05542|0|hsa:64118|DUS1L, DUS1, PP3111; dihydrouridine synthase 1-like (S. cerevisiae); K05542 tRNA-dihydrouridine synthase 1 [EC:1.3.1.88] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Dihydrouridine synthase (Dus)	tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like GN=DUS1L OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like [Equus caballus] 
ENSG00000169727(GPS1)	--	63.29725369	2296	56.74308893	2108	63.50867074	2373	62.34490964	2287	67.60463487	2535	61.71956836	2274	0.987771843	-0.036474084	normal	0.962121118	0.244524167	normal	0.987015835	-0.069725892	normal	0.866051976	0.04536437	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12175|0|ptr:747173|GPS1; G protein pathway suppressor 1; K12175 COP9 signalosome complex subunit 1 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	26S proteasome subunit RPN7;; PCI domain	COP9 signalosome complex subunit 1 GN=GPS1 OS=Homo sapiens (Human) PE=1 SV=4	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: COP9 signalosome complex subunit 1 [Leptonychotes weddellii]
ENSG00000169733(RFNG)	--	18.633483	564	16.979946	523	16.20173	536	16.420356	525	19.0244296	608	17.369469	551	0.963661486	-0.133831997	normal	0.950222644	0.195309645	normal	0.972265685	0.031440383	normal	0.928141344	0.032239243	normal	--	--	"Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	K05948|0|hsa:5986|RFNG; RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (EC:2.4.1.222); K05948 fringe [EC:2.4.1.222] (A)	Other types of O-glycan biosynthesis (ko00514);; Notch signaling pathway (ko04330)	--	--	Fringe-like	"Beta-1,3-N-acetylglucosaminyltransferase radical fringe GN=RFNG OS=Homo sapiens (Human) PE=2 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-N-acetylglucosaminyltransferase radical fringe, partial [Lipotes vexillifer]"
ENSG00000169738(DCXR)	--	32.40264463	502	22.776163	380	27.73140242	459	33.03158949	524	43.84901716	617	30.0598805	457	0.971567049	0.030954455	normal	0.029881939	0.675714832	normal	0.970897949	-0.014543409	normal	0.388731016	0.231636798	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K03331|9.5253e-165|hsa:51181|DCXR, DCR, HCR2, HCRII, KIDCR, P34H, PNTSU, SDR20C1, XR; dicarbonyl/L-xylulose reductase (EC:1.1.1.10); K03331 L-xylulose reductase [EC:1.1.1.10] (A)"	Pentose and glucuronate interconversions (ko00040)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase;; KR domain;; NADH(P)-binding;; Shikimate / quinate 5-dehydrogenase	L-xylulose reductase GN=DCXR OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: L-xylulose reductase [Trichechus manatus latirostris]
ENSG00000169740(ZNF32)	--	13.15179853	289	11.7555331	270	13.18694422	296	11.809583	271	12.26607802	271	13.34838629	299	0.960587288	-0.1229338	normal	0.966265631	-0.016003643	normal	0.967824239	0.006225221	normal	0.915487858	-0.044605275	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; TFIIH C1-like domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 32 GN=ZNF32 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 32 isoformX16 [Canis lupus familiaris] 
ENSG00000169750(RAC3)	--	17.055001	270	9.931680779	159	10.29390053	179	12.98058787	220	20.668419	343	8.283031551	133	0.887481831	-0.324239869	normal	2.84E-05	1.080593091	up	0.819852177	-0.432569177	normal	0.864506776	0.172844052	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07861|3.44025e-131|nle:100602123|RAC3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); K07861 Ras-related C3 botulinum toxin substrate 3 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Sphingolipid signaling pathway (ko04071);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Natural killer cell mediated cytotoxicity (ko04650);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Choline metabolism in cancer (ko05231);; Viral myocarditis (ko05416)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Ras-related C3 botulinum toxin substrate 3 (Precursor) GN=RAC3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras-related C3 botulinum toxin substrate 3 [Camelus bactrianus]
ENSG00000169752(NRG4)	--	0.432932528	7	0.54958824	9	1.375741366	22	0.715274131	12	1.155919305	19	0.871814819	15	--	--	--	--	--	--	0.981168735	-0.517520013	normal	--	--	--	--	--	--	"K05458|2.76361e-69|hsa:145957|NRG4, HRG4; neuregulin 4; K05458 neuregulin 4 (A)"	ErbB signaling pathway (ko04012)	--	--	--	Neuregulin-4 GN=NRG4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	"PREDICTED: pro-neuregulin-4, membrane-bound isoform [Orycteropus afer afer]"
ENSG00000169756(LIMS1)	--	23.18992477	1615	30.05770726	1789	23.97842045	1602	24.29342366	1402	19.62759729	1252	20.31614515	1383	0.955236556	-0.234640238	normal	0.220628126	-0.535800865	normal	0.960257933	-0.220140555	normal	0.038976172	-0.331783511	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	LIM and senescent cell antigen-like-containing domain protein 1 GN=LIMS1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: LIM and senescent cell antigen-like-containing domain protein 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000169758(TMEM266)	--	0.346188101	15	0.201568504	9	0.174383544	7	0.136754972	6	0.2692103	12	0.287362201	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein C15orf27 GN=C15orf27 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein C15orf27 homolog [Ceratotherium simum simum]
ENSG00000169760(NLGN1)	--	0.032491876	2	0.015653076	2	0.074161688	1	0.037361207	2	0.054802888	5	0.088927431	8	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K07378|0|hsa:22871|NLGN1, NL1; neuroligin 1; K07378 neuroligin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	Neuroligin-1 (Precursor) GN=NLGN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuroligin-1 isoform 3 [Trichechus manatus latirostris] 
ENSG00000169762(TAPT1)	--	4.05386173	275	3.580835346	248	3.980787858	271	5.765278593	399	5.641622579	385	6.6301753	455	0.466562745	0.503776361	normal	0.169215077	0.610083701	normal	0.013876531	0.736077706	normal	0.003183677	0.621230006	normal	--	--	--	--	--	[S]	Function unknown	Eukaryotic membrane protein family	Transmembrane anterior posterior transformation protein 1 homolog GN=TAPT1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane anterior posterior transformation protein 1 homolog [Ceratotherium simum simum]
ENSG00000169764(UGP2)	--	79.68737661	2621	65.22402619	2524	71.981337	2520	57.82542265	2192	65.45802824	2259	57.49578829	2098	0.941470976	-0.288516576	normal	0.977682082	-0.181339277	normal	0.949500007	-0.272520993	normal	0.147476847	-0.248330118	normal	[G]	Carbohydrate transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: uridylyltransferase activity (GO:0070569);; 	K00963|0|tup:102497956|UGP2; UDP-glucose pyrophosphorylase 2; K00963 UTP--glucose-1-phosphate uridylyltransferase [EC:2.7.7.9] (A)	Pentose and glucuronate interconversions (ko00040);; Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	UTP--glucose-1-phosphate uridylyltransferase	UTP--glucose-1-phosphate uridylyltransferase GN=UGP2 OS=Homo sapiens (Human) PE=1 SV=5	G	Carbohydrate transport and metabolism	PREDICTED: UTP--glucose-1-phosphate uridylyltransferase isoform X1 [Tupaia chinensis] 
ENSG00000169783(LINGO1)	--	1.57487301	92	1.952484633	69	1.993316527	86	1.814348462	99	2.916547292	149	1.721611395	95	0.970335404	0.073774597	normal	0.004291557	1.072845515	up	0.968045253	0.133072192	normal	0.282485155	0.452810613	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Immunoglobulin I-set domain;; Leucine rich repeat;; Immunoglobulin domain;; Leucine Rich repeat	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (Precursor) GN=LINGO1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 [Orcinus orca]
ENSG00000169813(HNRNPF)	--	134.279185	5367	126.28705	5421	131.36148	5408	154.8764	6641	153.26952	6288	154.11053	6354	0.972386559	0.276381112	normal	0.987312764	0.192565738	normal	0.983534057	0.224220593	normal	0.212544083	0.230357283	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12898|0|ptr:466053|HNRNPF, HNRPF; heterogeneous nuclear ribonucleoprotein F; K12898 heterogeneous nuclear ribonucleoprotein F/H (A)"	--	[A]	RNA processing and modification	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNPHF zinc finger;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"Heterogeneous nuclear ribonucleoprotein F, N-terminally processed GN=HNRNPF OS=Homo sapiens (Human) PE=1 SV=3"	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein F [Oryctolagus cuniculus] 
ENSG00000169814(BTD)	--	7.710464001	482	5.340132475	398	8.9400647	553	8.398904021	612	9.512925686	695	7.478240055	522	0.878547966	0.312779717	normal	0.002595414	0.78054618	normal	0.968732814	-0.09126419	normal	0.18416393	0.330945631	normal	--	--	"Biological Process: nitrogen compound metabolic process (GO:0006807);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds (GO:0016810);; "	K01435|0|hsa:686|BTD; biotinidase (EC:3.5.1.12); K01435 biotinidase [EC:3.5.1.12] (A)	Biotin metabolism (ko00780);; Vitamin digestion and absorption (ko04977)	[E]	Amino acid transport and metabolism	Carbon-nitrogen hydrolase	Biotinidase (Precursor) GN=BTD OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: biotinidase isoform X1 [Equus caballus]
ENSG00000169826(CSGALNACT2)	--	8.742208949	534	9.354944522	571	8.73281236	523	9.037791	553	7.51806269	455	12.04773315	732	0.972421525	0.019552195	normal	0.836128009	-0.348015733	normal	0.462390497	0.47557362	normal	0.87495885	0.075472339	normal	--	--	Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: Golgi cisterna membrane (GO:0032580);; 	K00746|0|ptr:450416|CSGALNACT2; chondroitin sulfate N-acetylgalactosaminyltransferase 2; K00746 chondroitin sulfate N-acetylgalactosaminyltransferase 1/2 [EC:2.4.1.174 2.4.1.175] (A)	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[G]	Carbohydrate transport and metabolism	Chondroitin N-acetylgalactosaminyltransferase;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Chondroitin sulfate N-acetylgalactosaminyltransferase 2 GN=CSGALNACT2 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: chondroitin sulfate N-acetylgalactosaminyltransferase 2 [Sus scrofa]
ENSG00000169836(TACR3)	--	0	0	0	0	0.0126539	0	0	0	0.0120653	0	0.01234	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04224|0|hsa:6870|TACR3, HH11, NK-3R, NK3R, NKR, TAC3RL; tachykinin receptor 3; K04224 tachykinin receptor 3 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuromedin-K receptor GN=TACR3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuromedin-K receptor [Pantholops hodgsonii]
ENSG00000169851(PCDH7)	--	2.4786907	264	2.782139308	316	2.775408273	287	3.305645772	372	3.438302759	371	3.250706234	371	0.617882918	0.461659416	normal	0.942159888	0.209143548	normal	0.832982585	0.360402369	normal	0.168175461	0.340395525	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16498|0|hsa:5099|PCDH7, BH-Pcdh, BHPCDH, PPP1R120; protocadherin 7; K16498 protocadherin delta 1 (A)"	--	--	--	Cadherin domain;; Protocadherin;; Cadherin-like	Protocadherin-7 (Precursor) GN=PCDH7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protocadherin-7-like isoform 1 [Tursiops truncatus]
ENSG00000169855(ROBO1)	--	3.94428251	674	3.571803565	594	3.81116968	605	13.47277867	2241	16.80975059	2781	12.75507192	2141	0	1.700239231	up	0	2.202791343	up	0	1.812416519	up	1.08E-19	1.913967254	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06753|0|mcf:102127979|ROBO1; roundabout, axon guidance receptor, homolog 1 (Drosophila); K06753 roundabout, axon guidance receptor 1 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Roundabout homolog 1 (Precursor) GN=ROBO1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: roundabout homolog 1 isoform X2 [Equus caballus]
ENSG00000169856(ONECUT1)	--	0.27396659	22	0.356953	27	0.386763	21	0.441528	26	0.5048326	36	0.736840451	55	0.986095546	0.197479904	normal	0.973612216	0.375353023	normal	0.094773629	1.319949901	normal	0.249620548	0.721796684	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K08026|0|ssc:100152052|ONECUT1; one cut homeobox 1; K08026 one cut domain, family member 1, hepatocyte nuclear factor 6 (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550);; Maturity onset diabetes of the young (ko04950)	[K]	Transcription	CUT domain;; Homeobox domain	Hepatocyte nuclear factor 6 GN=ONECUT1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: hepatocyte nuclear factor 6 isoform X1 [Sus scrofa]
ENSG00000169857(AVEN)	--	10.84547838	297	14.399053	417	13.82667	396	14.23071009	396	12.08567	331	13.157599	357	0.794101536	0.38248668	normal	0.837263837	-0.353201447	normal	0.956475585	-0.157235072	normal	0.884613309	-0.055651439	normal	--	--	--	--	--	--	--	--	Cell death regulator Aven GN=AVEN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cell death regulator Aven [Pteropus alecto]
ENSG00000169860(P2RY1)	--	1.68133	172	2.29841	235	1.65013	167	1.18618	122	1.16722	119	1.26538	130	0.683519822	-0.520805894	normal	0.001168938	-0.993958495	normal	0.889975465	-0.365862755	normal	0.030206963	-0.651057087	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04270|0|hsa:5028|P2RY1, P2Y1; purinergic receptor P2Y, G-protein coupled, 1; K04270 purinergic receptor P2Y, G protein-coupled, 1 (A)"	Rap1 signaling pathway (ko04015);; Neuroactive ligand-receptor interaction (ko04080);; Platelet activation (ko04611)	--	--	7 transmembrane receptor (rhodopsin family)	P2Y purinoceptor 1 GN=P2RY1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: P2Y purinoceptor 1-like [Tursiops truncatus]
ENSG00000169862(CTNND2)	--	0	0	0	0	0	0	0	0	0	0	0.015026629	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat;; HEAT repeats	Catenin delta-2 GN=CTNND2 OS=Homo sapiens (Human) PE=1 SV=3	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: catenin delta-2 [Odobenus rosmarus divergens]
ENSG00000169871(TRIM56)	--	12.83377298	2179	13.78289272	2541	12.90928746	2487	12.14401031	2151	9.80393449	1991	12.7285521	2428	0.986981606	-0.049455836	normal	0.842874157	-0.373078179	normal	0.988254635	-0.042903124	normal	0.430320405	-0.154308458	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12026|0|hsa:81844|TRIM56, RNF109; tripartite motif containing 56; K12026 tripartite motif-containing protein 56 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"B-box zinc finger;; RING-type zinc-finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRIM56 GN=TRIM56 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM56 isoform X1 [Pteropus alecto] 
ENSG00000169876(MUC17)	--	0	0	0.00358968	1	0.00351181	0	0.00353282	1	0.00335967	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SEA domain	Mucin-17 (Precursor) GN=MUC17 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mucin-17 [Equus caballus]
ENSG00000169884(WNT10B)	--	1.410483125	54	1.39842583	55	1.025325118	40	1.537097166	59	1.575986064	60	0.926611764	33	0.976588475	0.094354548	normal	0.97461655	0.10143355	normal	0.976928556	-0.274387083	normal	1	0.005616669	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K01357|0|hgl:101722280|Wnt10b; wingless-type MMTV integration site family, member 10B; K01357 wingless-type MMTV integration site family, member 10 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-10b (Precursor) GN=WNT10B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-10b [Chrysochloris asiatica]
ENSG00000169885(CALML6)	--	0.26002178	5	0.555286744	7	0.098510998	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K02183|1.80329e-132|hsa:163688|CALML6, CAGLP; calmodulin-like 6; K02183 calmodulin (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Phototransduction (ko04744);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Alzheimer's disease (ko05010);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Pertussis (ko05133);; Tuberculosis (ko05152);; Glioma (ko05214)	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain	Calmodulin-like protein 6 GN=CALML6 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: calmodulin-like protein 6 isoform X4 [Panthera tigris altaica]
ENSG00000169891(REPS2)	--	1.072977806	136	0.864779433	110	0.869014763	106	1.90438491	240	2.032928757	259	1.89080511	241	0.037856076	0.781864792	normal	1.15E-05	1.202929638	up	3.37E-05	1.165349011	up	4.17E-05	1.050602221	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cytoskeletal-regulatory complex EF hand	RalBP1-associated Eps domain-containing protein 2 GN=REPS2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ralBP1-associated Eps domain-containing protein 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000169894(MUC3A)	--	0.131861444	31	0.095098902	21	0.074362471	16	0.497982977	113	0.498371864	117	0.365054914	87	1.40E-06	1.785779765	up	1.62E-10	2.375681931	up	4.72E-08	2.329647569	up	2.07E-08	2.198322933	up	--	--	--	--	--	--	--	SEA domain	Mucin-3B (Precursor; Fragments) GN=MUC3B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: mucin-3A-like [Tupaia chinensis]
ENSG00000169895(SYAP1)	--	14.470732	1498	15.228404	1577	15.404257	1575	18.950064	1969	17.54156	1809	16.788759	1739	0.836970514	0.36326739	normal	0.973050809	0.176425131	normal	0.978899652	0.134491721	normal	0.203067423	0.225106914	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	BSD domain	Synapse-associated protein 1 GN=SYAP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synapse-associated protein 1-like isoform X1 [Physeter catodon]
ENSG00000169896(ITGAM)	--	0.344163534	28	0.240465612	23	0.411349125	35	0.615847105	52	0.651607465	62	0.834110994	53	0.783637288	0.82843661	normal	0.039070433	1.353020118	normal	0.924132479	0.570194674	normal	0.06936445	0.937024603	normal	--	--	--	"K06461|0|hsa:3684|ITGAM, CD11B, CR3A, MAC-1, MAC1A, MO1A, SLEB6; integrin, alpha M (complement component 3 receptor 3 subunit); K06461 integrin alpha M (A)"	Rap1 signaling pathway (ko04015);; Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Hematopoietic cell lineage (ko04640);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Amoebiasis (ko05146);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Transcriptional misregulation in cancer (ko05202)	[W]	Extracellular structures	Integrin alpha;; von Willebrand factor type A domain;; FG-GAP repeat;; Integrin alpha cytoplasmic region	Integrin alpha-M (Precursor) GN=ITGAM OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin alpha-M [Galeopterus variegatus]
ENSG00000169902(TPST1)	--	6.780662288	302	5.682887985	249	5.327461004	235	7.208777721	309	6.76	308	4.455573865	190	0.967890745	0.002214885	normal	0.910710206	0.283805773	normal	0.902752387	-0.312710374	normal	0.983948554	0.015376629	normal	[R]	General function prediction only	Molecular Function: sulfotransferase activity (GO:0008146);; 	K01021|0|ptr:472398|TPST1; tyrosylprotein sulfotransferase 1 (EC:2.8.2.20); K01021 protein-tyrosine sulfotransferase [EC:2.8.2.20] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase family;; Sulfotransferase domain	Protein-tyrosine sulfotransferase 1 GN=TPST1 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-tyrosine sulfotransferase 1 [Tupaia chinensis]
ENSG00000169903(TM4SF4)	--	0.499165541	15	0.661655712	20	0.265419249	7	7.662846443	232	10.460955	308	6.674857313	201	0	3.790626055	up	0	3.826142773	up	0	4.564794809	up	4.58E-20	4.118212138	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	L6 membrane protein	Transmembrane 4 L6 family member 4 GN=TM4SF4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane 4 L6 family member 4 [Felis catus] 
ENSG00000169905(TOR1AIP2)	--	17.602415	1567	14.520547	1603	19.442091	1806	18.455664	1741	15.53518507	1426	17.76734728	1621	0.980179363	0.120966206	normal	0.968486632	-0.190036785	normal	0.975546185	-0.16406016	normal	0.747230811	-0.076823283	normal	--	--	--	--	--	--	--	Lamina-associated polypeptide 1C (LAP1C)	Torsin-1A-interacting protein 2 GN=TOR1AIP2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: torsin-1A-interacting protein 2-like [Galeopterus variegatus]
ENSG00000169908(TM4SF1)	--	216.2676734	4707	260.5019375	5656	244.3494241	5245	273.7491845	5975	208.8665087	4522	303.61125	6637	0.953419985	0.313207679	normal	0.931000318	-0.344144535	normal	0.945457542	0.331211978	normal	0.743694397	0.11357399	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	L6 membrane protein	Transmembrane 4 L6 family member 1 GN=TM4SF1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane 4 L6 family member 1 isoform X1 [Panthera tigris altaica]
ENSG00000169914(OTUD3)	--	2.365048213	245	2.01883294	210	2.048154187	208	2.27844866	235	2.517010173	264	2.232072448	232	0.963674803	-0.090374491	normal	0.900955655	0.306748207	normal	0.957498086	0.14822894	normal	0.758998567	0.119577983	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K13717|0|hsa:23252|OTUD3, DUBA4; OTU deubiquitinase 3 (EC:3.4.19.12); K13717 OTU domain-containing protein 3 [EC:3.4.19.12] (A)"	--	--	--	OTU-like cysteine protease	OTU domain-containing protein 3 GN=OTUD3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: OTU domain-containing protein 3 [Ceratotherium simum simum]
ENSG00000169918(OTUD7A)	--	3.3741337	39	2.199141294	37	1.96851867	26	1.380342176	17	2.3348345	26	2.657174684	25	0.586362609	-1.157824133	normal	0.961644283	-0.505659744	normal	0.98634879	-0.06124203	normal	0.376445801	-0.605578499	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	"K11860|0|hsa:161725|OTUD7A, C15orf16, C16ORF15, CEZANNE2, OTUD7; OTU deubiquitinase 7A (EC:3.4.19.12); K11860 OTU domain-containing protein 7 [EC:3.4.19.12] (A)"	--	[T]	Signal transduction mechanisms	OTU-like cysteine protease;; UBA-like domain	OTU domain-containing protein 7A GN=OTUD7A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: OTU domain-containing protein 7A [Odobenus rosmarus divergens]
ENSG00000169919(GUSB)	--	15.95333162	689	13.01865335	568	14.23533927	601	16.13125345	699	18.28962307	788	18.75830006	807	0.975253744	-0.010021604	normal	0.570471253	0.449857159	normal	0.671272716	0.416005753	normal	0.147570267	0.283346129	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K01195|0|hsa:2990|GUSB, BG, MPS7; glucuronidase, beta (EC:3.2.1.31); K01195 beta-glucuronidase [EC:3.2.1.31] (A)"	Pentose and glucuronate interconversions (ko00040);; Starch and sucrose metabolism (ko00500);; Glycosaminoglycan degradation (ko00531);; Porphyrin and chlorophyll metabolism (ko00860);; Drug metabolism - other enzymes (ko00983);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolases family 2, TIM barrel domain;; Glycosyl hydrolases family 2, sugar binding domain;; Glycosyl hydrolases family 2"	Beta-glucuronidase (Precursor) GN=GUSB OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	beta-glucuronidase precursor [Felis catus] 
ENSG00000169925(BRD3)	--	12.31646668	1342	14.97614477	1622	15.60673441	1654	15.0375294	1566	15.735955	1673	15.30805009	1678	0.967460425	0.191664	normal	0.984478041	0.023215755	normal	0.985099154	0.01248071	normal	0.778228833	0.069711676	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	"K11721|0|hsa:8019|BRD3, ORFX, RING3L; bromodomain containing 3; K11721 bromodomain-containing protein 3 (A)"	--	[K]	Transcription	Bromodomain	Bromodomain-containing protein 3 GN=BRD3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: bromodomain-containing protein 3 [Erinaceus europaeus]
ENSG00000169926(KLF13)	--	29.53856267	3740	27.84427859	3546	25.938256	3362	23.32176448	2954	21.99332022	2792	25.03642095	3185	0.867408602	-0.371028733	normal	0.877918832	-0.366143706	normal	0.989353378	-0.086277915	normal	0.102132058	-0.274812935	normal	[R]	General function prediction only	--	K09208|9.36166e-131|ptr:453286|KLF13; Kruppel-like factor 13; K09208 krueppel-like factor 9/13/14/16 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 13 GN=KLF13 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	Kruppel-like factor 13 [Sus scrofa]
ENSG00000169933(FRMPD4)	--	0	0	0	0	0	0	0.034876151	3	0.055665377	6	0.012157133	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	FERM central domain;; PDZ domain (Also known as DHR or GLGF)	FERM and PDZ domain-containing protein 4 GN=FRMPD4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: FERM and PDZ domain-containing protein 4 isoform 1 [Ceratotherium simum simum]
ENSG00000169946(ZFPM2)	--	0.0815365	7	0.2500537	19	0.204720556	16	0.320849	13	0.0973836	7	0.057953	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17442|0|hsa:23414|ZFPM2, DIH3, FOG2, SRXY9, ZC2HC11B, ZNF89B, hFOG-2; zinc finger protein, FOG family member 2; K17442 zinc finger protein ZFPM2 (A)"	MicroRNAs in cancer (ko05206)	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; Zinc finger, C2H2 type"	Zinc finger protein ZFPM2 GN=ZFPM2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger protein ZFPM2 isoform X1 [Mustela putorius furo]
ENSG00000169951(ZNF764)	--	7.353175563	405	6.437638312	356	6.532261307	352	5.644202748	316	7.584389894	392	6.02505116	342	0.781639988	-0.387161882	normal	0.961729519	0.117075787	normal	0.967648079	-0.049654112	normal	0.749214567	-0.105042052	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:103784241|ZNF764; zinc finger protein 764; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; LYAR-type C2HC zinc finger"	Zinc finger protein 764 GN=ZNF764 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 764-like isoform X1 [Tupaia chinensis] 
ENSG00000169957(ZNF768)	--	25.89674064	1131	26.28701655	1156	24.904459	1117	20.38192193	914	20.21925485	862	23.63745742	1038	0.856254681	-0.337653723	normal	0.583811513	-0.444132694	normal	0.975280091	-0.113954099	normal	0.088027309	-0.295496297	normal	[R]	General function prediction only	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: DNA-directed RNA polymerase II, core complex (GO:0005665);; Biological Process: transcription from RNA polymerase II promoter (GO:0006366);; "	K09228|0|hsa:79724|ZNF768; zinc finger protein 768; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; Drought induced 19 protein (Di19), zinc-binding;; XPA protein N-terminal;; RNA polymerase Rpb1 C-terminal repeat"	Zinc finger protein 768 GN=ZNF768 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 768 [Vicugna pacos]
ENSG00000169962(TAS1R3)	--	0.17887	11	0.15814	10	0.0926344	5	0.178332	11	0.110238	6	0.272903	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04626|0|hsa:83756|TAS1R3, T1R3; taste receptor, type 1, member 3; K04626 taste receptor type 1 member 3 (A)"	Taste transduction (ko04742);; Carbohydrate digestion and absorption (ko04973)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Nine Cysteines Domain of family 3 GPCR;; Periplasmic binding protein	Taste receptor type 1 member 3 (Precursor) GN=TAS1R3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: taste receptor type 1 member 3 [Galeopterus variegatus]
ENSG00000169964(TMEM42)	--	10.63988	139	10.172563	137	9.212115	124	9.96186	131	10.035152	131	9.67484	127	0.964519181	-0.115040177	normal	0.965014783	-0.085075149	normal	0.968742359	0.025884992	normal	0.917992512	-0.061685747	normal	--	--	--	--	--	--	--	--	Transmembrane protein 42 GN=TMEM42 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 42 [Galeopterus variegatus]
ENSG00000169967(MAP3K2)	--	7.345994568	1083	8.480204712	1431	7.44673146	1062	7.13600595	1050	9.093614023	1166	7.369078343	1072	0.978153328	-0.075367579	normal	0.896185028	-0.316511151	normal	0.980349661	0.005222296	normal	0.617115539	-0.142565992	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04420|0|nle:100601802|MAP3K2; mitogen-activated protein kinase kinase kinase 2; K04420 mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25] (A)	MAPK signaling pathway (ko04010);; Gap junction (ko04540);; GnRH signaling pathway (ko04912)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PB1 domain	Mitogen-activated protein kinase kinase kinase 2 GN=MAP3K2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 2 [Galeopterus variegatus]
ENSG00000169972(PUSL1)	--	8.4944	169	6.97159	129	7.268974	148	11.4224	203	11.8104	223	9.101217	177	0.942027655	0.231700223	normal	0.066599746	0.761378497	normal	0.940479767	0.247544937	normal	0.196887235	0.413660593	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	--	--	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	tRNA pseudouridine synthase	tRNA pseudouridine synthase-like 1 GN=PUSL1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA pseudouridine synthase-like 1 isoform X3 [Tupaia chinensis]
ENSG00000169976(SF3B5)	--	102.21	898	95.8495	844	109.497	984	123.724	1101	112.522	989	125.178	1114	0.930937224	0.262788247	normal	0.954434002	0.206958111	normal	0.966522135	0.170481181	normal	0.270092678	0.212121032	normal	--	--	--	"K12832|1.45614e-60|umr:103666941|SF3B5; splicing factor 3b, subunit 5, 10kDa; K12832 splicing factor 3B subunit 5 (A)"	Spliceosome (ko03040)	[S]	Function unknown	Splicing factor 3B subunit 10 (SF3b10)	Splicing factor 3B subunit 5 GN=SF3B5 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: splicing factor 3B subunit 5 [Tupaia chinensis]
ENSG00000169981(ZNF35)	--	2.558054029	185	2.2419121	177	2.018630118	196	2.354626385	175	2.806387924	236	1.895639673	178	0.962733574	-0.110062581	normal	0.833047715	0.390711177	normal	0.958659243	-0.146084583	normal	0.909622586	0.057168808	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; CpXC protein;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 35 GN=ZNF35 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: zinc finger protein 197 [Ceratotherium simum simum]
ENSG00000169989(TIGD4)	--	0.242887	10	0.409569	17	0.337894	13	0.237693	10	0.235011	9	0.144447	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; Tc5 transposase DNA-binding domain;; CENP-B N-terminal DNA-binding domain	Tigger transposable element-derived protein 4 GN=TIGD4 OS=Homo sapiens (Human) PE=2 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: tigger transposable element-derived protein 4 [Panthera tigris altaica]
ENSG00000169991(IFFO2)	--	7.973549	908	7.673808895	916	10.77243553	1278	11.34934227	1325	10.01961924	1122	6.1228693	685	0.277785754	0.513672576	normal	0.927232728	0.270822038	normal	1.93E-05	-0.906513963	normal	0.996057513	-0.008485557	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	--	--	--	--	Intermediate filament protein	Intermediate filament family orphan 2 GN=IFFO2 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: intermediate filament family orphan 2 isoform X1 [Canis lupus familiaris]
ENSG00000169992(NLGN2)	--	24.47692236	2440	19.034648	1920	22.242792	2236	14.75153909	1381	20.85865495	1748	15.157316	1447	5.27E-05	-0.851277216	normal	0.97732725	-0.15669827	normal	0.025716127	-0.635607994	normal	0.001838268	-0.548352521	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	K07378|0|mcf:102122460|NLGN2; neuroligin 2; K07378 neuroligin (A)	Cell adhesion molecules (CAMs) (ko04514)	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	Neuroligin-2 (Precursor) GN=NLGN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuroligin-2 isoform X1 [Erinaceus europaeus]
ENSG00000169994(MYO7B)	--	0	0	0.006599669	1	0	0	0.054261415	4	0.078621994	5	0.013352693	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoskeleton (GO:0005856);; Cellular Component: myosin complex (GO:0016459);; 	K10359|0|hsa:4648|MYO7B; myosin VIIB; K10359 myosin VII (A)	--	[N]	Cell motility	Myosin head (motor domain);; MyTH4 domain;; FERM central domain;; IQ calmodulin-binding motif;; FERM N-terminal domain;; Variant SH3 domain	Unconventional myosin-VIIb GN=MYO7B OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-VIIb [Odobenus rosmarus divergens]
ENSG00000170004(CHD3)	--	38.23990381	5397	34.66899901	5278	38.47069604	5458	45.01956901	6272	48.60789415	6696	50.46300278	7481	0.988076709	0.185886487	normal	0.953531718	0.321799591	normal	0.738868599	0.44646121	normal	0.058538531	0.321404409	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: histone deacetylation (GO:0016575);; Molecular Function: hydrolase activity (GO:0016787);; Cellular Component: HDA1 complex (GO:0070823);; 	"K11642|0|hsa:1107|CHD3, Mi-2a, Mi2-ALPHA, ZFH; chromodomain helicase DNA binding protein 3 (EC:3.6.4.12); K11642 chromodomain-helicase-DNA-binding protein 3 [EC:3.6.4.12] (A)"	--	[R]	General function prediction only	"CHDCT2 (NUC038) domain;; SNF2 family N-terminal domain;; Domain of Unknown Function (DUF1086);; CHDNT (NUC034) domain;; Domain of Unknown Function (DUF1087);; PHD-finger;; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain;; Class II histone deacetylase complex subunits 2 and 3;; Type III restriction enzyme, res subunit"	Chromodomain-helicase-DNA-binding protein 3 GN=CHD3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: chromodomain-helicase-DNA-binding protein 3 [Orcinus orca]
ENSG00000170006(TMEM154)	--	0	0	0	0	0	0	1.336237389	97	0.677366003	84	1.2008949	95	0	5.987863745	up	0	5.810840858	up	0	5.991832455	up	5.25E-28	Inf	up	--	--	--	--	--	--	--	TMEM154 protein family	Transmembrane protein 154 (Precursor) GN=TMEM154 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 154 [Dasypus novemcinctus]
ENSG00000170011(MYRIP)	--	0.068075124	7	0.079358066	8	0.071627782	4	0.027543025	3	0.029848706	2	0.039606806	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Rab effector MyRIP/melanophilin C-terminus;; FYVE-type zinc finger	Rab effector MyRIP GN=MYRIP OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: rab effector MyRIP [Equus caballus]
ENSG00000170017(ALCAM)	--	65.2511	5336	74.50773014	6001	67.78453	5413	61.941223	5120	58.98114793	4830	83.26617776	6884	0.992495781	-0.090420537	normal	0.941529686	-0.334512127	normal	0.94140501	0.338443229	normal	0.978007411	-0.013218189	normal	--	--	--	K06547|0|pps:100984029|ALCAM; activated leukocyte cell adhesion molecule; K06547 activated leukocyte cell adhesion molecule (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin C1-set domain	CD166 antigen (Precursor) GN=ALCAM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: CD166 antigen isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000170027(YWHAG)	--	133.623	8402	142.451	9001	144.247	9054	165.794	10511	149.872	9407	151.499	9555	0.976520842	0.292215121	normal	0.995676518	0.042215916	normal	0.995584254	0.06939784	normal	0.555452923	0.134288062	normal	[T]	Signal transduction mechanisms	--	"K16198|2.56192e-174|ngi:103733474|Ywhag; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma; K16198 14-3-3 protein gamma/eta (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; PI3K-Akt signaling pathway (ko04151);; Hippo signaling pathway (ko04390);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein	"14-3-3 protein gamma, N-terminally processed GN=YWHAG OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 14-3-3 protein gamma [Chrysochloris asiatica]
ENSG00000170035(UBE2E3)	--	41.96904916	894	37.44046087	826	37.45750272	809	34.41043496	734	33.46898265	729	28.8541868	582	0.880769181	-0.314728919	normal	0.953261589	-0.201256995	normal	0.425547923	-0.482343983	normal	0.07151807	-0.328371727	normal	--	--	--	K06689|1.22817e-109|umr:103659630|UBE2E3; ubiquitin-conjugating enzyme E2E 3; K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 E3 GN=UBE2E3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 E3 isoform X1 [Equus przewalskii]
ENSG00000170037(CNTROB)	--	13.22687799	944	13.77897994	826	13.97574121	940	12.83031599	712	11.96618302	681	8.381313192	620	0.593349746	-0.436919949	normal	0.897454751	-0.299308956	normal	0.063273496	-0.607471704	normal	0.006917164	-0.450401735	normal	--	--	--	"K16468|0|hsa:116840|CNTROB, LIP8; centrobin, centrosomal BRCA2 interacting protein; K16468 centrobin (A)"	--	--	--	--	Centrobin GN=CNTROB OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centrobin isoform 1 [Trichechus manatus latirostris]
ENSG00000170043(TRAPPC1)	--	177.50084	1933	157.1685	1738	170.12147	1900	187.33527	2071	193.114156	2083	182.574095	2007	0.985611859	0.06860097	normal	0.959262571	0.239617534	normal	0.985302062	0.070695002	normal	0.554751699	0.124043291	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: TRAPP complex (GO:0030008);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sybindin-like family	Trafficking protein particle complex subunit 1 GN=TRAPPC1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 1 isoform X1 [Vicugna pacos] 
ENSG00000170044(ZPLD1)	--	0	0	0	0	0	0	0.093551005	5	0.057435314	3	0.044046964	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zona pellucida-like domain	Zona pellucida-like domain-containing protein 1 (Precursor) GN=ZPLD1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: zona pellucida-like domain-containing protein 1-like [Myotis brandtii]
ENSG00000170049(KCNAB3)	--	0.478459	22	0.507613	24	0.397627	18	0.452782	21	0.736759	34	0.578934	27	0.98825661	-0.091411341	normal	0.970306174	0.456790755	normal	0.974476459	0.539450619	normal	0.704308168	0.336780944	normal	[C]	Energy production and conversion	--	"K04884|0|nle:100585187|KCNAB3; potassium voltage-gated channel, shaker-related subfamily, beta member 3; K04884 potassium voltage-gated channel Shaker-related subfamily A, beta member 3 (A)"	--	[C]	Energy production and conversion	Aldo/keto reductase family	Voltage-gated potassium channel subunit beta-3 GN=KCNAB3 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-gated potassium channel subunit beta-3 [Orycteropus afer afer]
ENSG00000170074(FAM153A)	--	0	0	0.024643025	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM153B GN=FAM153B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000170075(GPR37L1)	--	0.14624	18	0.23114	29	0.14177	17	0.130903	16	0.182641	22	0.3064	38	--	--	--	0.977809359	-0.396181993	normal	0.701765693	1.086024079	normal	0.835102099	0.228642591	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04244|0|hsa:9283|GPR37L1, ET(B)R-LP-2, ETBR-LP-2; G protein-coupled receptor 37 like 1; K04244 endothelin type b receptor-like protein 2 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Prosaposin receptor GPR37L1 (Precursor) GN=GPR37L1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: endothelin B receptor-like protein 2 [Ceratotherium simum simum]
ENSG00000170085(SIMC1)	--	7.469065673	473	7.09927264	440	7.644285654	472	6.566450473	390	5.28963285	348	3.941316359	245	0.884570013	-0.308094124	normal	0.827654702	-0.35845392	normal	0.000101871	-0.949995069	normal	0.012008937	-0.517038539	normal	--	--	--	--	--	--	--	--	SUMO-interacting motif-containing protein 1 GN=SIMC1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: SUMO-interacting motif-containing protein 1 [Orcinus orca]
ENSG00000170088(TMEM192)	--	7.40608	480	8.85369	467	6.121557	469	9.33253	542	7.85519	524	11.70552669	648	0.961295484	0.143992271	normal	0.960299604	0.144276463	normal	0.545730913	0.456855954	normal	0.249812651	0.254854951	normal	--	--	--	--	--	--	--	TMEM192 family	Transmembrane protein 192 GN=TMEM192 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: transmembrane protein 192, partial [Orycteropus afer afer]"
ENSG00000170091(HMP19)	--	0	0	0	0	0	0	0	0	0	0	0.043010318	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: dopamine receptor signaling pathway (GO:0007212);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: clathrin light chain binding (GO:0032051);; Biological Process: clathrin coat assembly (GO:0048268);; 	--	--	--	--	D1 dopamine receptor-interacting protein (calcyon)	Neuron-specific protein family member 2 GN=NSG2 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: neuron-specific protein family member 2-like [Elephantulus edwardii]
ENSG00000170092(SPDYE5)	--	0.9853535	42	0.8458974	42	1.616158001	70	0.491817046	27	0.715983	30	1.22711778	49	0.93241642	-0.638875726	normal	0.957170564	-0.486048482	normal	0.910183277	-0.509636422	normal	0.360398524	-0.557285471	normal	--	--	--	--	--	--	--	Cell cycle regulatory protein	Putative speedy protein E6 GN=SPDYE6 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: speedy protein E4-like [Ursus maritimus]
ENSG00000170099(SERPINA6)	--	0.33184794	5	0.035674072	1	0.0702698	1	0.573833555	16	1.496939985	36	0.782422157	22	--	--	--	2.73E-06	3.88575688	up	0.008435881	3.220813744	up	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Corticosteroid-binding globulin (Precursor) GN=SERPINA6 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: corticosteroid-binding globulin [Galeopterus variegatus]
ENSG00000170100(ZNF778)	--	2.128307508	242	2.244788273	294	1.976616788	248	1.609367875	195	3.1943709	252	1.977879132	247	0.880868343	-0.339955264	normal	0.931180633	-0.242470269	normal	0.967097854	-0.014034765	normal	0.55303736	-0.196527941	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:197320|ZNF778; zinc finger protein 778; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; NTF2 fold immunity protein"	Zinc finger protein 778 GN=ZNF778 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 778-like [Galeopterus variegatus]
ENSG00000170113(NIPA1)	--	20.6718814	2002	23.5985	2103	21.50407	1912	15.910283	1440	16.236736	1454	19.3542781	1758	0.314315005	-0.505745443	normal	0.168135856	-0.553366642	normal	0.980752314	-0.129332178	normal	0.010256984	-0.391933806	normal	--	--	Molecular Function: magnesium ion transmembrane transporter activity (GO:0015095);; Biological Process: magnesium ion transport (GO:0015693);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Magnesium transporter NIPA	Magnesium transporter NIPA1 GN=NIPA1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: magnesium transporter NIPA1 isoform X3 [Canis lupus familiaris]
ENSG00000170122(FOXD4)	--	0.648677	20	0.638841	20	0.523653	16	0.80732	25	0.965204	30	0.790023	25	0.985618203	0.272354789	normal	0.969817012	0.530594278	normal	0.974284721	0.590596642	normal	0.541095963	0.493098482	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09397|0|hsa:2298|FOXD4, FKHL9, FOXD4A, FREAC-5, FREAC5; forkhead box D4; K09397 forkhead box protein D (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein D4 GN=FOXD4 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: forkhead box protein D4 [Bos mutus]
ENSG00000170128(GPR25)	--	0	0	0	0	0	0	0.0822442	1	0	0	0.164129	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08405|0|hsa:2848|GPR25; G protein-coupled receptor 25; K08405 G protein-coupled receptor 25 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 25 GN=GPR25 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 25 [Orycteropus afer afer]
ENSG00000170142(UBE2E1)	--	105.1979901	2115	99.89815057	1922	93.660935	1921	103.4978401	2042	101.80151	2069	94.42285	1910	0.985452056	-0.081446839	normal	0.984529175	0.084834408	normal	0.98641729	-0.016563246	normal	0.986272296	-0.006254945	normal	--	--	--	K06689|1.0821e-115|cge:100767156|Ube2e1; ubiquitin-conjugating enzyme E2E 1; K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 E1 GN=UBE2E1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 E1 isoform X1 [Erinaceus europaeus]
ENSG00000170144(HNRNPA3)	--	188.0375286	8684	198.2241505	9403	205.8614287	9568	157.7395503	7320	153.7091842	6955	124.2445936	5607	0.977597635	-0.277294823	normal	0.753758198	-0.456411456	normal	0.000652388	-0.779116936	normal	0.0016621	-0.497929628	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12741|1.24711e-136|mmu:229279|Hnrnpa3, 2410013L13Rik, 2610209F03Rik, 2610510D13Rik, Hnrpa3; heterogeneous nuclear ribonucleoprotein A3; K12741 heterogeneous nuclear ribonucleoprotein A1/A3 (A)"	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoprotein A3 GN=HNRNPA3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein A3-like isoform X2 [Chrysochloris asiatica]
ENSG00000170145(SIK2)	--	3.23363	625	3.37684	650	3.79822	728	3.64853	699	4.06632	781	3.99035	770	0.966547106	0.130301019	normal	0.935382086	0.242940031	normal	0.974042513	0.072482134	normal	0.534412931	0.147132826	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16311|0|hsa:23235|SIK2, LOH11CR1I, QIK, SNF1LK2; salt-inducible kinase 2 (EC:2.7.11.1); K16311 serine/threonine-protein kinase SIK2 [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase SIK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase SIK2 [Galeopterus variegatus]
ENSG00000170153(RNF150)	--	1.78001802	249	1.73640003	237	2.092651089	216	0.804445588	130	1.229673388	195	0.917334462	153	0.001407384	-0.960115381	normal	0.907984922	-0.300720252	normal	0.653065615	-0.50159737	normal	0.036460608	-0.575232642	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; PA domain;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 150 (Precursor) GN=RNF150 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 150 [Ceratotherium simum simum]
ENSG00000170160(CCDC144A)	--	8.035927324	2856	8.44279132	2950	11.66061964	2892	7.661694995	2585	7.362397507	2537	7.870281544	2812	0.980670446	-0.174565195	normal	0.967672504	-0.238885791	normal	0.989353061	-0.048736553	normal	0.435292501	-0.153601621	normal	--	--	--	--	--	--	--	CCDC144C protein coiled-coil region;; Domain of unknown function (DUF3496)	Coiled-coil domain-containing protein 144A GN=CCDC144A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	Ankyrin repeat domain-containing protein 26 [Pteropus alecto]
ENSG00000170162(VGLL2)	--	0	0	0	0	0	0	0.0585044	2	0	0	0.035014691	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	Vestigial/Tondu family	Transcription cofactor vestigial-like protein 2 GN=VGLL2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription cofactor vestigial-like protein 2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000170166(HOXD4)	--	0.337144	8	0.909013	22	0.161072	3	0.53442	13	0.283759	6	0.328303	8	--	--	--	0.609875312	-1.664672686	normal	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09304|6.73021e-122|hsa:3233|HOXD4, HHO.C13, HOX-5.1, HOX4, HOX4B, Hox-4.2; homeobox D4; K09304 homeobox protein HoxA/B/C/D4 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-D4 GN=HOXD4 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-D4 [Pteropus alecto] 
ENSG00000170175(CHRNB1)	--	5.908495375	117	4.280528716	84	5.351344003	102	6.96994185	140	6.318808181	127	5.113551872	103	0.951502115	0.225377729	normal	0.713864506	0.566591626	normal	0.970600566	0.00569965	normal	0.564982649	0.266223326	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04812|0|hsa:1140|CHRNB1, ACHRB, CHRNB, CMS1D, CMS2A, SCCMS; cholinergic receptor, nicotinic, beta 1 (muscle); K04812 nicotinic acetylcholine receptor beta-1 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel transmembrane region;; Neurotransmitter-gated ion-channel ligand binding domain	Acetylcholine receptor subunit beta (Precursor) GN=CHRNB1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: acetylcholine receptor subunit beta isoform X1 [Galeopterus variegatus]
ENSG00000170185(USP38)	--	5.284448	453	5.65686479	503	5.431294937	460	7.105566198	611	7.76185	657	7.063501213	605	0.727994703	0.399658196	normal	0.810553661	0.36295111	normal	0.761749348	0.385900293	normal	0.048962148	0.382264283	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11854|0|pps:100990061|USP38; ubiquitin specific peptidase 38; K11854 ubiquitin carboxyl-terminal hydrolase 35/38 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 38 GN=USP38 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 38 [Mustela putorius furo]
ENSG00000170190(SLC16A5)	--	28.541839	806	25.995335	735	27.14932904	786	24.12938	696	27.44885678	769	28.901909	811	0.936468136	-0.242027741	normal	0.97489834	0.043724835	normal	0.976463498	0.036811432	normal	0.856751286	-0.052626995	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08182|0|pps:100969614|SLC16A5; solute carrier family 16 (monocarboxylate transporter), member 5; K08182 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 5 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Monocarboxylate transporter 6 GN=SLC16A5 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 6 [Tupaia chinensis] 
ENSG00000170191(NANP)	--	8.078377692	486	7.430164769	446	6.99032207	413	7.89142	478	8.31763	500	7.687027324	464	0.970033358	-0.054603891	normal	0.960025768	0.142999702	normal	0.957180867	0.159141531	normal	0.802953995	0.079028632	normal	[R]	General function prediction only	--	"K01097|0|hsa:140838|NANP, C20orf147, HDHD4, dJ694B14.3; N-acetylneuraminic acid phosphatase (EC:3.1.3.29); K01097 N-acylneuraminate-9-phosphatase [EC:3.1.3.29] (A)"	Amino sugar and nucleotide sugar metabolism (ko00520)	[R]	General function prediction only	Haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; Protein of unknown function (DUF705)	N-acylneuraminate-9-phosphatase GN=NANP OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: N-acylneuraminate-9-phosphatase [Ceratotherium simum simum]
ENSG00000170209(ANKK1)	--	0.0365097	2	0.0179688	1	0.0175871	0	0.0366571	2	0	0	0.0181011	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16289|0|hsa:255239|ANKK1, PKK2; ankyrin repeat and kinase domain containing 1 (EC:2.7.11.1); K16289 ankyrin repeat and protein kinase domain-containing protein 1 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Protein tyrosine kinase;; Protein kinase domain	Ankyrin repeat and protein kinase domain-containing protein 1 GN=ANKK1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: ankyrin repeat and protein kinase domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000170214(ADRA1B)	--	5.455818218	203	4.793029219	205	4.074873546	190	7.762743	307	9.305765	364	9.165358	354	0.355454589	0.562443209	normal	0.008020982	0.802388494	normal	0.001471931	0.884221392	normal	0.000647848	0.756563203	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04136|0|hsa:147|ADRA1B, ADRA1, ALPHA1BAR; adrenoceptor alpha 1B; K04136 adrenergic receptor alpha-1B (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Neuroactive ligand-receptor interaction (ko04080);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Salivary secretion (ko04970)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Alpha-1B adrenergic receptor GN=ADRA1B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: alpha-1B adrenergic receptor [Mustela putorius furo] 
ENSG00000170222(ADPRM)	--	6.566989035	145	5.7242677	122	6.920722004	134	5.2197898	134	6.944450027	163	6.35514705	151	0.961740763	-0.14307453	normal	0.871963381	0.392343859	normal	0.959255444	0.162297739	normal	0.777925229	0.139170838	normal	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	"K01517|0|hsa:56985|ADPRM, C17orf48, NBLA03831; ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent (EC:3.6.1.13 3.6.1.16 3.6.1.53); K01517 manganese-dependent ADP-ribose/CDP-alcohol diphosphatase [EC:3.6.1.13 3.6.1.16 3.6.1.53] (A)"	Purine metabolism (ko00230);; Glycerophospholipid metabolism (ko00564)	--	--	Calcineurin-like phosphoesterase	Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase GN=ADPRM OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: manganese-dependent ADP-ribose/CDP-alcohol diphosphatase isoform X1 [Equus caballus] 
ENSG00000170231(FABP6)	--	0	0	0	0	0	0	1.062724414	14	2.071339	16	0.624212034	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08755|1.26903e-121|hsa:2172|FABP6, I-15P, I-BABP, I-BALB, I-BAP, ILBP, ILBP3, ILLBP; fatty acid binding protein 6, ileal; K08755 fatty acid-binding protein 6, ileal (gastrotropin) (A)"	PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family	Gastrotropin GN=FABP6 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: gastrotropin isoform X1 [Tupaia chinensis] 
ENSG00000170234(PWWP2A)	--	6.096143014	389	5.790293064	364	6.118888347	392	6.411589708	416	6.366009432	401	6.81861492	430	0.967777569	0.065730047	normal	0.961810991	0.117770935	normal	0.962385147	0.124731975	normal	0.74863308	0.102092296	normal	--	--	--	--	--	--	--	PWWP domain	PWWP domain-containing protein 2A GN=PWWP2A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: PWWP domain-containing protein 2A isoform X1 [Orycteropus afer afer]
ENSG00000170236(USP50)	--	0.170780931	4	0.128430353	3	0.04268942	0	0.0848059	2	0.1654907	3	0.084699094	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Inactive ubiquitin carboxyl-terminal hydrolase 50 GN=USP50 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: putative ubiquitin carboxyl-terminal hydrolase 50-like [Dasypus novemcinctus]
ENSG00000170242(USP47)	--	13.89713	1504	15.375253	1637	15.517061	1643	16.377286	1764	16.550864	1792	16.450336	1783	0.967878406	0.199025849	normal	0.981305529	0.1089935	normal	0.981617019	0.109585931	normal	0.50648397	0.137269244	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11857|0|mcf:102126415|USP47; ubiquitin specific peptidase 47; K11857 ubiquitin carboxyl-terminal hydrolase 47 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin-like domain	Ubiquitin carboxyl-terminal hydrolase 47 GN=USP47 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 47 isoform 1 [Odobenus rosmarus divergens]
ENSG00000170248(PDCD6IP)	--	38.52707876	3740	41.5806937	3898	41.66813235	3873	52.58338986	5254	58.41763648	5706	53.21154404	5092	0.635795407	0.459385773	normal	0.341500574	0.528148798	normal	0.861800688	0.386357513	normal	0.002550666	0.458528931	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K12200|0|hsa:10015|PDCD6IP, AIP1, ALIX, DRIP4, HP95; programmed cell death 6 interacting protein; K12200 programmed cell death 6-interacting protein (A)"	Endocytosis (ko04144)	[R]	General function prediction only	BRO1-like domain;; ALIX V-shaped domain binding to HIV	Programmed cell death 6-interacting protein GN=PDCD6IP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: programmed cell death 6-interacting protein isoform 1 [Ceratotherium simum simum]
ENSG00000170260(ZNF212)	--	4.921976	276	4.465518657	259	4.479710227	262	5.109801	293	5.420089	302	5.494857628	310	0.966270188	0.055102412	normal	0.945264861	0.199092513	normal	0.935502927	0.23317131	normal	0.620426589	0.162302885	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7988|ZNF212, C2H2-150, ZNF182, ZNFC150; zinc finger protein 212; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc finger protein;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein 212 GN=ZNF212 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 212 [Oryctolagus cuniculus]
ENSG00000170264(FAM161A)	--	7.800439483	528	8.6600853	580	8.675329568	573	4.687482277	323	5.00408121	334	4.960554225	326	0.009278073	-0.737063973	normal	0.00164563	-0.814794478	normal	0.001279752	-0.819050099	normal	1.19E-05	-0.795157362	normal	--	--	--	"K16772|0|hsa:84140|FAM161A, RP28; family with sequence similarity 161, member A; K16772 protein FAM161A (A)"	--	--	--	Uncharacterised protein family UPF0564	Protein FAM161A GN=FAM161A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM161A isoform X2 [Galeopterus variegatus]
ENSG00000170265(ZNF282)	--	12.536918	885	13.14108327	959	11.72420606	863	13.636092	968	14.15071	992	15.05346	1041	0.974657445	0.098334068	normal	0.978512635	0.027340357	normal	0.930662502	0.261827837	normal	0.573132395	0.127646384	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:745636|ZNF282; zinc finger protein 282; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; Zinc finger protein;; C2H2-type zinc finger"	Zinc finger protein 282 GN=ZNF282 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 282 [Oryctolagus cuniculus]
ENSG00000170266(GLB1)	--	38.71130885	1877	37.56935617	1796	34.54689189	1691	47.9854381	2299	47.76059104	2330	58.88942846	2851	0.951966868	0.261551842	normal	0.870005268	0.353853804	normal	0.001396608	0.744781253	normal	0.003992995	0.45903577	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: beta-galactosidase activity (GO:0004565);; Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: beta-galactosidase complex (GO:0009341);; 	"K12309|0|hsa:2720|GLB1, EBP, ELNR1, MPS4B; galactosidase, beta 1 (EC:3.2.1.23); K12309 beta-galactosidase [EC:3.2.1.23] (A)"	Galactose metabolism (ko00052);; Other glycan degradation (ko00511);; Glycosaminoglycan degradation (ko00531);; Sphingolipid metabolism (ko00600);; Glycosphingolipid biosynthesis - ganglio series (ko00604);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 35;; Beta-galactosidase;; Beta-galactosidase jelly roll domain	Beta-galactosidase (Precursor) GN=GLB1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: beta-galactosidase [Galeopterus variegatus]
ENSG00000170270(GON7)	--	10.2539	166	11.079887	180	15.105812	225	13.7776	232	11.4909	186	12.8216	211	0.749727112	0.448583197	normal	0.965690606	0.025667022	normal	0.962947046	-0.100277314	normal	0.781587836	0.118467913	normal	--	--	Cellular Component: EKC/KEOPS complex (GO:0000408);; 	--	--	--	--	Domain of unknown function (DUF4611)	Uncharacterized protein C14orf142 GN=C14orf142 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C14orf142 homolog [Equus przewalskii]
ENSG00000170271(FAXDC2)	--	0.095395188	6	0.095821297	6	0	0	0.2072186	14	0.263108508	16	0.04715	3	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Molecular Function: iron ion binding (GO:0005506);; Biological Process: lipid biosynthetic process (GO:0008610);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07750|0|hsa:10826|FAXDC2, C5orf4; fatty acid hydroxylase domain containing 2; K07750 methylsterol monooxygenase [EC:1.14.13.72] (A)"	Steroid biosynthesis (ko00100)	[I]	Lipid transport and metabolism	Fatty acid hydroxylase superfamily	Fatty acid hydroxylase domain-containing protein 2 GN=FAXDC2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: fatty acid hydroxylase domain-containing protein 2 isoform X1 [Loxodonta africana]
ENSG00000170275(CRTAP)	--	126.590418	6860	122.1829981	6401	121.918468	6408	150.1907677	8482	147.2284118	8277	162.0358311	9144	0.977348413	0.275308108	normal	0.942575994	0.349311341	normal	0.503165809	0.504559623	normal	0.024676028	0.376168336	normal	--	--	--	--	--	[S]	Function unknown	--	Cartilage-associated protein (Precursor) GN=CRTAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cartilage-associated protein [Ceratotherium simum simum]
ENSG00000170276(HSPB2)	--	0.141563	3	0	0	0.0909505	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural constituent of eye lens (GO:0005212);; 	K09543|6.64616e-116|mcf:102127928|HSPB2; heat shock 27kDa protein 2; K09543 heat shock protein beta-2 (A)	Epstein-Barr virus infection (ko05169);; Proteoglycans in cancer (ko05205)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp20/alpha crystallin family	Heat shock protein beta-2 GN=HSPB2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein beta-2 [Bos mutus] 
ENSG00000170290(SLN)	--	0.316933209	1	0.206167634	2	0	0	0.353285186	3	1.032164798	9	0.328545218	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sarcolipin GN=SLN OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sarcolipin [Odobenus rosmarus divergens] 
ENSG00000170291(ELP5)	--	52.91847442	732	51.93222272	818	57.10104003	823	45.64823406	785	44.46557019	719	53.55798151	856	0.974253417	0.069875105	normal	0.951196455	-0.207126849	normal	0.97665743	0.048339823	normal	0.928019045	-0.028812486	normal	--	--	--	--	--	--	--	Elongator subunit Iki1	Elongator complex protein 5 GN=ELP5 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: elongator complex protein 5 [Ceratotherium simum simum]
ENSG00000170293(CMTM8)	--	21.14684714	297	21.57861695	307	17.94071205	258	14.04285093	200	18.139701	238	15.5797239	223	0.25528065	-0.597501632	normal	0.809921073	-0.386534677	normal	0.942387188	-0.217247801	normal	0.126667074	-0.404124723	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	CKLF-like MARVEL transmembrane domain-containing protein 8 GN=CMTM8 OS=Homo sapiens (Human) PE=2 SV=2	V	Defense mechanisms	PREDICTED: CKLF-like MARVEL transmembrane domain-containing protein 8 isoform X2 [Balaenoptera acutorostrata scammoni] 
ENSG00000170296(GABARAP)	--	209.983462	3433	228.52315	3398	202.784408	3262	227.085781	3431	227.75988	3645	263.349009	4297	0.991006333	-0.031658822	normal	0.989885539	0.079772122	normal	0.842219205	0.389123897	normal	0.453694847	0.151662853	normal	--	--	Biological Process: autophagic vacuole assembly (GO:0000045);; Cellular Component: cytoplasm (GO:0005737);; 	K08341|4.11462e-80|ngi:103752156|Gabarap; GABA(A) receptor-associated protein; K08341 GABA(A) receptor-associated protein (A)	FoxO signaling pathway (ko04068);; Regulation of autophagy (ko04140);; GABAergic synapse (ko04727)	[Z]	Cytoskeleton	Autophagy protein Atg8 ubiquitin like;; Ubiquitin-like autophagy protein Apg12	Gamma-aminobutyric acid receptor-associated protein (Precursor) GN=GABARAP OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: gamma-aminobutyric acid receptor-associated protein [Mustela putorius furo] 
ENSG00000170298(LGALS9B)	--	0.064661831	2	0.0319848	1	0.125542892	3	0	0	0	0	0.0319452	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	"K10093|0|hsa:284194|LGALS9B; lectin, galactoside-binding, soluble, 9B; K10093 galectin-9 (A)"	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-9B GN=LGALS9B OS=Homo sapiens (Human) PE=2 SV=3	W	Extracellular structures	PREDICTED: galectin-9 isoform X2 [Camelus dromedarius]
ENSG00000170310(STX8)	--	43.77725501	626	37.68674973	522	38.33335004	549	40.30751	578	42.271087	604	39.15956	566	0.962946118	-0.145553501	normal	0.952091795	0.188563982	normal	0.972413076	0.035607858	normal	0.956592571	0.021457952	normal	--	--	--	K08501|3.6182e-135|ptr:455082|STX8; syntaxin 8; K08501 syntaxin 8 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain	Syntaxin-8 GN=STX8 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-8 [Tupaia chinensis]
ENSG00000170312(CDK1)	--	74.12809514	1873	67.32711685	1681	75.7450791	1869	72.21937731	1876	63.13798748	1597	59.73079407	1520	0.986052388	-0.028499975	normal	0.981742863	-0.095294	normal	0.914777577	-0.306211428	normal	0.492637279	-0.140939395	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02087|0|pps:100996071|CDK1; cyclin-dependent kinase 1; K02087 cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23] (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; p53 signaling pathway (ko04115);; Gap junction (ko04540);; Progesterone-mediated oocyte maturation (ko04914);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 1 GN=CDK1 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 1 isoformX1 [Canis lupus familiaris] 
ENSG00000170315(UBB)	--	792.3248431	9725	753.6672299	9395	641.0285134	7582	656.5889599	7653	790.8256249	9291	906.5571803	11973	0.921981862	-0.376437884	normal	0.99576335	-0.037479769	normal	0.033448047	0.650738716	normal	0.84356216	0.094737488	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K04551|3.18547e-162|ssc:100125968|UBB; ubiquitin B; K04551 ubiquitin B (A)	Parkinson's disease (ko05012)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin-like domain;; Telomere stability and silencing;; Ubiquitin-2 like Rad60 SUMO-like;; DUF2407 ubiquitin-like domain;; GLUT4 regulating protein TUG;; Protein of unknown function (DUF2870)	Ubiquitin (Precursor) GN=UBB OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polyubiquitin-C isoform X2 [Lipotes vexillifer] 
ENSG00000170322(NFRKB)	--	5.666853409	528	4.891050773	535	4.888892987	524	5.409194217	509	5.531405571	533	4.904071	470	0.968895009	-0.083457165	normal	0.971438457	-0.026754149	normal	0.957197031	-0.164695345	normal	0.757973181	-0.091250203	normal	--	--	--	K11671|0|ggo:101124157|NFRKB; nuclear factor related to kappa-B-binding protein; K11671 nuclear factor related to kappa-B-binding protein (A)	--	[K]	Transcription	NFRKB Winged Helix-like	Nuclear factor related to kappa-B-binding protein GN=NFRKB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear factor related to kappa-B-binding protein isoform 1 [Ceratotherium simum simum]
ENSG00000170323(FABP4)	--	0.202106	3	0	0	0	0	0.267955	4	0.0658164	0	0.200849	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08753|1.08883e-90|ptr:464255|FABP4; fatty acid binding protein 4, adipocyte; K08753 fatty acid-binding protein 4, adipocyte (A)"	PPAR signaling pathway (ko03320)	[I]	Lipid transport and metabolism	Lipocalin / cytosolic fatty-acid binding protein family;; Lipocalin / cytosolic fatty-acid binding protein family	"Fatty acid-binding protein, adipocyte GN=FABP4 OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: fatty acid-binding protein, adipocyte [Tupaia chinensis]"
ENSG00000170324(FRMPD2)	--	0.066709543	6	0.021884862	2	0.04061672	3	0.033383481	3	0.074517479	6	0.11348768	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; FERM central domain;; FERM C-terminal PH-like domain;; FERM N-terminal domain;; PDZ domain	FERM and PDZ domain-containing protein 2 GN=FRMPD2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: FERM and PDZ domain-containing protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000170325(PRDM10)	--	1.635763574	210	2.266026003	288	2.091813663	264	2.126721136	226	2.036177176	259	2.618548825	336	0.96478895	0.074575187	normal	0.951308912	-0.173581565	normal	0.86543364	0.337912143	normal	0.858551034	0.087635555	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	PR domain zinc finger protein 10 GN=PRDM10 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: PR domain zinc finger protein 10 isoform 1 [Ceratotherium simum simum]
ENSG00000170340(B3GNT2)	--	20.60707604	942	17.0565047	779	18.065523	817	11.37136321	521	11.65846137	531	10.05192894	459	6.77E-05	-0.883308371	normal	0.1455464	-0.572981903	normal	0.000340166	-0.83803459	normal	1.45E-06	-0.769760208	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K00741|0|ptr:745838|B3GNT2; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2; K00741 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149] (A)"	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 GN=B3GNT2 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 [Chrysochloris asiatica]"
ENSG00000170345(FOS)	--	0.858430402	22	1.205551601	41	0.670399852	25	0.621338461	19	0.516409937	19	1.337147479	20	0.987487411	-0.225382342	normal	0.64031985	-1.071647199	normal	0.984301266	-0.309263735	normal	0.389155108	-0.623022439	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K04379|0|hsa:2353|FOS, AP-1, C-FOS, p55; FBJ murine osteosarcoma viral oncogene homolog; K04379 proto-oncogene protein c-fos (A)"	MAPK signaling pathway (ko04010);; cAMP signaling pathway (ko04024);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; TNF signaling pathway (ko04668);; Circadian entrainment (ko04713);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Oxytocin signaling pathway (ko04921);; Amphetamine addiction (ko05031);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Choline metabolism in cancer (ko05231);; Rheumatoid arthritis (ko05323)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Proto-oncogene c-Fos GN=FOS OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: proto-oncogene c-Fos isoform 1 [Odobenus rosmarus divergens] 
ENSG00000170348(TMED10)	--	81.96995399	4689	83.241032	4734	75.87135	4244	80.016305	4599	82.65748825	4704	84.7975	4847	0.992526187	-0.058772899	normal	0.992751794	-0.030588401	normal	0.985796716	0.18331482	normal	0.919930835	0.028893822	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 10 (Precursor) GN=TMED10 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 10 [Tupaia chinensis] 
ENSG00000170364(SETMAR)	--	4.384886601	187	3.514336321	158	3.520369843	139	4.6485193	207	5.303425716	250	3.813761884	171	0.961884493	0.11486303	normal	0.236524963	0.635700741	normal	0.928602033	0.287792345	normal	0.274519506	0.353858613	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; 	K11433|0|pps:100986203|SETMAR; histone-lysine N-methyltransferase SETMAR; K11433 histone-lysine N-methyltransferase SETMAR [EC:2.1.1.43] (A)	Lysine degradation (ko00310)	--	--	Transposase (partial DDE domain);; SET domain;; Pre-SET motif;; DDE superfamily endonuclease;; Homeodomain-like domain;; Transposase;; Transposase	Transposon Hsmar1 transposase {ECO:0000303|PubMed:9461395} OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: mariner-like transposase isoform X1 [Bos taurus]
ENSG00000170365(SMAD1)	--	5.99831947	266	5.85644535	256	5.310699062	231	6.44038683	279	6.163258885	293	6.994180512	314	0.966805092	0.037793461	normal	0.951556941	0.172377919	normal	0.724110729	0.432144623	normal	0.490280938	0.213622913	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04676|0|cjc:100402435|SMAD1; SMAD family member 1; K04676 mothers against decapentaplegic homolog 1 (A)	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Transcriptional misregulation in cancer (ko05202)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain;; Interferon-regulatory factor 3	Mothers against decapentaplegic homolog 1 GN=SMAD1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	mothers against decapentaplegic homolog 1 [Sus scrofa] 
ENSG00000170369(CST2)	--	0.206409	2	0	0	0.294163	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	K13898|1.16714e-76|hsa:1470|CST2; cystatin SA; K13898 cystatin-SA (A)	Salivary secretion (ko04970)	--	--	Cystatin domain	Cystatin-SA (Precursor) GN=CST2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cystatin-C-like [Loxodonta africana]
ENSG00000170373(CST1)	--	0.3242884	3	0.616684082	6	0	0	0.09917574	1	0.100893	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cysteine-type endopeptidase inhibitor activity (GO:0004869);; 	K13897|7.47018e-87|hsa:1469|CST1; cystatin SN; K13897 cystatin-SN (A)	Salivary secretion (ko04970)	--	--	Cystatin domain	Cystatin-SN (Precursor) GN=CST1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: cystatin-C-like [Eptesicus fuscus]
ENSG00000170374(SP7)	--	0.03981148	2	0.039292762	2	0	0	0.019960479	1	0	0	0.07878425	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09197|0|ptr:467004|SP7; Sp7 transcription factor; K09197 transcription factor Sp7 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Transcription factor Sp7 GN=SP7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor Sp7 isoform 1 [Ceratotherium simum simum]
ENSG00000170379(TCAF2)	--	0.546333237	31	0.23823335	14	0.438389858	13	1.032211223	55	0.801202545	38	0.448983486	21	0.814032015	0.767438663	normal	0.393115451	1.328917984	normal	0.978443725	0.62585678	normal	0.276499796	0.950293309	normal	--	--	--	--	--	--	--	Peptidase M60-like family	Protein FAM115C GN=FAM115C OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM115C-like [Galeopterus variegatus]
ENSG00000170381(SEMA3E)	--	1.454561081	121	2.086436867	175	2.549939	151	4.147879004	372	5.269240116	329	3.99994417	359	1.67E-11	1.577462284	up	0.002342304	0.88364953	normal	3.62E-07	1.232890002	up	1.64E-08	1.224329083	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06840|0|pps:100982463|SEMA3E; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E; K06840 semaphorin 3 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Semaphorin-3E (Precursor) GN=SEMA3E OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-3E [Tupaia chinensis]
ENSG00000170382(LRRN2)	--	4.295016265	300	4.31697592	308	4.138705303	291	5.202736935	365	6.263291179	433	4.625373178	327	0.92658347	0.250935149	normal	0.577377881	0.46806336	normal	0.955328487	0.15919918	normal	0.231502474	0.302070001	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Immunoglobulin I-set domain;; Leucine Rich Repeat;; Leucine-rich repeat;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Leucine Rich repeat;; Immunoglobulin V-set domain;; Leucine rich repeat	Leucine-rich repeat neuronal protein 2 (Precursor) GN=LRRN2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat neuronal protein 2 [Galeopterus variegatus]
ENSG00000170385(SLC30A1)	--	18.0487	1371	17.7647	1347	14.9334	1111	18.0291	1388	23.5369	1791	19.4013	1477	0.983104467	-0.013038745	normal	0.782152464	0.389208835	normal	0.724425929	0.402043396	normal	0.243268033	0.260885239	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14688|0|hsa:7779|SLC30A1, ZNT1, ZRC1; solute carrier family 30 (zinc transporter), member 1; K14688 solute carrier family 30 (zinc transporter), member 1 (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Cation efflux family	Zinc transporter 1 GN=SLC30A1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter 1 [Galeopterus variegatus]
ENSG00000170390(DCLK2)	--	3.36156902	289	4.838332613	419	3.573895086	307	4.814615316	408	7.0911948	607	6.9249169	603	0.590343409	0.464579744	normal	0.366726465	0.51177703	normal	2.97E-05	0.962182962	normal	0.056508888	0.652416013	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	K08805|0|pps:100972828|DCLK2; doublecortin-like kinase 2; K08805 doublecortin-like kinase 1/2 [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Doublecortin;; Protein tyrosine kinase	Serine/threonine-protein kinase DCLK2 GN=DCLK2 OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase DCLK2 isoform 1 [Ceratotherium simum simum]
ENSG00000170396(ZNF804A)	--	0.120789242	11	0.332865651	30	0.209222854	18	0.208646047	19	0.224036425	17	0.063728769	5	--	--	--	0.935745952	-0.787468666	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-finger double-stranded RNA-binding	Zinc finger protein 804A GN=ZNF804A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 804A [Equus caballus]
ENSG00000170412(GPRC5C)	--	28.59488029	951	37.91509401	1087	30.97345499	1012	30.45759148	837	33.19811454	918	38.57614572	1220	0.951419388	-0.214679948	normal	0.930617341	-0.264810988	normal	0.935087078	0.261024673	normal	0.887671679	-0.056020336	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04620|0|ggo:101125552|GPRC5C; G-protein coupled receptor family C group 5 member C isoform 1; K04620 G protein-coupled receptor family C group 5 member C (A)	--	--	--	7 transmembrane sweet-taste receptor of 3 GCPR	G-protein coupled receptor family C group 5 member C (Precursor) GN=GPRC5C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor family C group 5 member C [Canis lupus familiaris]
ENSG00000170417(TMEM182)	--	3.180860038	129	2.842968262	112	3.6720626	141	2.03717511	83	2.44051293	94	1.323975747	52	0.509437192	-0.657177744	normal	0.946625263	-0.270204427	normal	2.57E-05	-1.421274483	down	0.034568522	-0.760161939	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin tight junction;; PMP-22/EMP/MP20/Claudin family	Transmembrane protein 182 (Precursor) GN=TMEM182 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 182 [Ceratotherium simum simum]
ENSG00000170421(KRT8)	--	1051.354892	42053	952.624477	38656	1060.718841	43480	1331.49044	53599	1372.344982	54737	1372.840651	54896	0.991220105	0.319154748	normal	0.884614565	0.480381583	normal	0.990140862	0.328047472	normal	0.080699865	0.37343161	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:3856|KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO; keratin 8; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 8 GN=KRT8 OS=Homo sapiens (Human) PE=1 SV=7"	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8 [Ovis aries]"
ENSG00000170423(KRT78)	--	0.020513654	1	0.052709026	2	0	0	0.020431403	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|pps:100969378|KRT78; keratin 78; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 78 GN=KRT78 OS=Homo sapiens (Human) PE=2 SV=2"	S	Function unknown	"PREDICTED: keratin, type II cytoskeletal 78 [Galeopterus variegatus]"
ENSG00000170425(ADORA2B)	--	20.59568	513	24.47029976	619	20.79388607	550	8.047858631	203	9.807867247	235	9.172787962	226	3.69E-10	-1.361585622	down	2.46E-11	-1.41287658	down	2.88E-09	-1.285701078	down	5.79E-14	-1.361834309	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04267|0|hsa:136|ADORA2B, ADORA2; adenosine A2b receptor; K04267 adenosine receptor A2b (A)"	Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Vascular smooth muscle contraction (ko04270);; Alcoholism (ko05034)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Adenosine receptor A2b GN=ADORA2B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	adenosine receptor A2b [Oryctolagus cuniculus] 
ENSG00000170426(SDR9C7)	--	0	0	0	0	0	0	0	0	0	0	0.0636026	2	--	--	--	--	--	--	--	--	--	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase	Short-chain dehydrogenase/reductase family 9C member 7 GN=SDR9C7 OS=Homo sapiens (Human) PE=2 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: short-chain dehydrogenase/reductase family 9C member 7 [Felis catus]
ENSG00000170430(MGMT)	--	46.04075	296	33.27449	227	36.61359	283	31.32006	244	35.47381	239	35.64902	209	0.896184941	-0.307785372	normal	0.964819841	0.05255056	normal	0.718436955	-0.442826138	normal	0.436464399	-0.241431962	normal	[L]	"Replication, recombination and repair"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: methylated-DNA-[protein]-cysteine S-methyltransferase activity (GO:0003908);; Biological Process: DNA repair (GO:0006281);; 	K00567|2.05538e-130|hsa:4255|MGMT; O-6-methylguanine-DNA methyltransferase (EC:2.1.1.63); K00567 methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63] (A)	--	[L]	"Replication, recombination and repair"	"6-O-methylguanine DNA methyltransferase, DNA binding domain;; 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain"	Methylated-DNA--protein-cysteine methyltransferase GN=MGMT OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: methylated-DNA--protein-cysteine methyltransferase isoform X1 [Tupaia chinensis]
ENSG00000170439(METTL7B)	--	4.532631	114	2.91344	75	3.20543	88	5.571895	140	6.91382	174	6.18687	161	0.943753322	0.262365593	normal	0.000323544	1.176686158	up	0.055287065	0.852208332	normal	0.019928819	0.757298686	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Cellular Component: nucleolus (GO:0005730);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; Hypothetical methyltransferase	Methyltransferase-like protein 7B (Precursor) GN=METTL7B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: methyltransferase-like protein 7B isoform X1 [Tupaia chinensis] 
ENSG00000170442(KRT86)	--	2.324205819	86	1.96593178	75	2.251163488	87	5.683239159	214	4.097620951	153	4.081245728	153	1.10E-05	1.269524023	up	0.011482216	0.992848241	normal	0.126824649	0.795591879	normal	0.00053782	1.045992232	up	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:3892|KRT86, HB6, Hb1, KRTHB1, KRTHB6, MNX, hHb6; keratin 86; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cuticular Hb6 GN=KRT86 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: keratin, type II cuticular Hb6 [Mustela putorius furo] "
ENSG00000170445(HARS)	--	32.99936516	1480	29.7028727	1432	32.77040302	1504	38.57796945	1791	41.0983622	1890	32.96687734	1487	0.953330129	0.244105267	normal	0.810662409	0.378579186	normal	0.983862396	-0.024666418	normal	0.258132191	0.205279762	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01892|0|ggo:101145423|HARS; histidine--tRNA ligase, cytoplasmic isoform 1; K01892 histidyl-tRNA synthetase [EC:6.1.1.21] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"Histidyl-tRNA synthetase;; tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain;; WHEP-TRS domain;; Anticodon binding domain of tRNAs"	"Histidine--tRNA ligase, cytoplasmic GN=HARS OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: histidine--tRNA ligase, cytoplasmic [Galeopterus variegatus]"
ENSG00000170448(NFXL1)	--	3.602651311	252	3.676461683	259	2.938823019	202	3.83648722	270	3.72677945	260	3.769334428	263	0.965304303	0.068301075	normal	0.966115668	-0.015775102	normal	0.846777636	0.369981904	normal	0.719693589	0.131732089	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	"K15683|0|hsa:152518|NFXL1, CDZFP, HOZFP, OZFP, URCC5; nuclear transcription factor, X-box binding-like 1; K15683 NF-X1-type zinc finger protein NFXL1 (A)"	--	[K]	Transcription	NF-X1 type zinc finger	NF-X1-type zinc finger protein NFXL1 GN=NFXL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: NF-X1-type zinc finger protein NFXL1 isoform X3 [Bubalus bubalis]
ENSG00000170456(DENND5B)	--	18.66624287	2416	15.39050632	2165	18.10398883	2429	11.14224146	1685	14.71466809	1807	10.804338	1398	0.159559326	-0.550282558	normal	0.940388726	-0.28198114	normal	0.000239805	-0.804620656	normal	0.000160005	-0.541092925	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; RUN domain;; uDENN domain;; dDENN domain;; PLAT/LH2 domain	DENN domain-containing protein 5B GN=DENND5B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 5B [Panthera tigris altaica]
ENSG00000170458(CD14)	--	5.324029129	149	3.53359629	99	3.305709717	90	3.463979935	94	6.918234381	191	6.1001965	158	0.347247125	-0.686416527	normal	0.012355529	0.916397427	normal	0.117790627	0.793446553	normal	0.577607009	0.370194581	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K04391|0|hsa:929|CD14; CD14 molecule; K04391 CD14 antigen (A)	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Phagosome (ko04145);; Toll-like receptor signaling pathway (ko04620);; Hematopoietic cell lineage (ko04640);; Regulation of actin cytoskeleton (ko04810);; Pathogenic Escherichia coli infection (ko05130);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Transcriptional misregulation in cancer (ko05202)	--	--	Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	"Monocyte differentiation antigen CD14, membrane-bound form (Precursor) GN=CD14 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: monocyte differentiation antigen CD14 [Galeopterus variegatus]
ENSG00000170464(DNAJC18)	--	3.125965989	265	3.170379296	256	2.864321025	225	3.05725201	283	3.687769229	313	3.074823572	272	0.965701718	0.063620471	normal	0.919519974	0.267162975	normal	0.924694635	0.263775491	normal	0.535298568	0.197031872	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09538|0|hsa:202052|DNAJC18; DnaJ (Hsp40) homolog, subfamily C, member 18; K09538 DnaJ homolog subfamily C member 18 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF1977);; DnaJ domain	DnaJ homolog subfamily C member 18 GN=DNAJC18 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	dnaJ homolog subfamily C member 18 [Bos taurus] 
ENSG00000170468(RIOX1)	--	7.53615	293	6.23688	248	7.7206	309	10.57	416	10.283	400	9.64746	378	0.560437647	0.472760802	normal	0.072097399	0.665011995	normal	0.90944533	0.281241505	normal	0.035889847	0.469072048	normal	--	--	--	"K16914|0|hsa:79697|C14orf169, MAPJD, NO66, ROX, hsNO66; chromosome 14 open reading frame 169 (EC:1.14.11.27); K16914 bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [EC:1.14.11.- 1.14.11.27] (A)"	--	[S]	Function unknown	Cupin superfamily protein;; Cupin-like domain	Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 GN=NO66 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66 [Equus caballus]
ENSG00000170469(SPATA24)	--	4.697408966	178	5.313395449	188	3.381868251	181	4.119045181	162	3.549188982	193	1.9098679	136	0.956885895	-0.165220026	normal	0.965768896	0.016312125	normal	0.836660219	-0.416644554	normal	0.668547181	-0.177385159	normal	--	--	--	--	--	--	--	Spermatogenesis-associated protein 24	Spermatogenesis-associated protein 24 GN=SPATA24 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: spermatogenesis-associated protein 24 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000170471(RALGAPB)	--	15.59229	2254	16.02150513	2289	15.539636	2291	14.10734874	2006	13.81630658	1897	15.01426916	2295	0.972767815	-0.19885438	normal	0.935585376	-0.292211916	normal	0.988089611	-0.005770941	normal	0.402102147	-0.161733663	normal	--	--	--	--	--	[S]	Function unknown	--	Ral GTPase-activating protein subunit beta GN=RALGAPB OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ral GTPase-activating protein subunit beta isoform X1 [Vicugna pacos]
ENSG00000170473(PYM1)	--	18.038684	366	14.590002	286	15.300865	333	22.488599	465	22.676742	460	18.0374	377	0.880087214	0.313385393	normal	0.060470143	0.661410338	normal	0.953568819	0.170024792	normal	0.089526467	0.380863602	normal	--	--	--	K14294|1.94061e-94|ptr:451975|WIBG; within bgcn homolog (Drosophila); K14294 partner of Y14 and mago (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[S]	Function unknown	Mago binding	Partner of Y14 and mago GN=WIBG OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: partner of Y14 and mago isoform X3 [Galeopterus variegatus]
ENSG00000170477(KRT4)	--	0.0367429	2	0.288041	16	0.0710096	3	0.018311	1	0.0179189	0	0.0914081	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:3851|KRT4, CK-4, CK4, CYK4, K4, WSN1; keratin 4; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 4 GN=KRT4 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: keratin, type II cytoskeletal 4 [Camelus dromedarius]"
ENSG00000170482(SLC23A1)	--	0.345608248	13	0.1844066	7	0.181623085	6	0.372950669	14	0.853275579	32	1.15820464	44	--	--	--	0.059060535	1.95803239	normal	8.84E-05	2.591612856	up	--	--	--	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14611|0|ptr:462104|SLC23A1, SLC23A2; solute carrier family 23 (ascorbic acid transporter), member 1; K14611 solute carrier family 23 (nucleobase transporter), member 1/2 (A)"	--	[F]	Nucleotide transport and metabolism	Permease family	Solute carrier family 23 member 1 GN=SLC23A1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 23 member 1 isoform X2 [Eptesicus fuscus]
ENSG00000170485(NPAS2)	--	44.52956496	3281	36.78856336	2754	40.68037378	3119	18.28449031	1278	18.55330182	1348	13.87331515	1047	5.66E-15	-1.389996302	down	6.60E-08	-1.051291119	down	0	-1.581722577	down	3.09E-24	-1.339033361	down	--	--	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09026|0|hsa:4862|NPAS2, MOP4, PASD4, bHLHe9; neuronal PAS domain protein 2; K09026 neuronal PAS domain-containing protein 2 (A)"	Circadian rhythm (ko04710)	[K]	Transcription	PAS domain;; PAS fold;; PAS fold;; Helix-loop-helix DNA-binding domain	Neuronal PAS domain-containing protein 2 GN=NPAS2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: neuronal PAS domain-containing protein 2 [Felis catus]
ENSG00000170500(LONRF2)	--	4.498895911	1024	4.686901428	1038	3.974677241	929	2.34352295	486	2.96333445	613	1.983515973	461	4.50E-08	-1.10355732	down	0.001321974	-0.779777654	normal	1.26E-06	-1.016804655	down	1.87E-10	-0.960465858	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATP-dependent protease La (LON) domain;; TPR repeat;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Ring finger domain;; Tetratricopeptide repeat;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Tetratricopeptide repeat;; Tetratricopeptide repeat"	LON peptidase N-terminal domain and RING finger protein 2 GN=LONRF2 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LON peptidase N-terminal domain and RING finger protein 2 [Odobenus rosmarus divergens]
ENSG00000170502(NUDT9)	--	15.30398492	480	15.2476798	470	14.96368056	475	12.36503013	419	14.50646237	426	17.03797273	523	0.937535814	-0.226140896	normal	0.955815003	-0.162683781	normal	0.963396322	0.130196822	normal	0.800513651	-0.079426225	normal	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	K13988|0|nle:100607477|NUDT9; nudix (nucleoside diphosphate linked moiety X)-type motif 9; K13988 ADP-ribose pyrophosphatase [EC:3.6.1.13] (A)	Purine metabolism (ko00230)	[P]	Inorganic ion transport and metabolism	NUDIX domain	"ADP-ribose pyrophosphatase, mitochondrial (Precursor) GN=NUDT9 OS=Homo sapiens (Human) PE=1 SV=1"	L	"Replication, recombination and repair"	"PREDICTED: ADP-ribose pyrophosphatase, mitochondrial [Tupaia chinensis]"
ENSG00000170509(HSD17B13)	--	0.058681024	2	0	0	0.176171537	5	0.053226203	2	0.028421387	0	0.106565673	4	--	--	--	--	--	--	--	--	--	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase	17-beta-hydroxysteroid dehydrogenase 13 (Precursor) GN=HSD17B13 OS=Homo sapiens (Human) PE=2 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 17-beta-hydroxysteroid dehydrogenase 13 isoform 1 [Ceratotherium simum simum]
ENSG00000170522(ELOVL6)	--	25.59297164	1706	28.108	1634	32.99754716	1614	21.66781915	1310	21.183095	1189	23.291884	1322	0.702047446	-0.411458797	normal	0.446565015	-0.47956313	normal	0.918589491	-0.295902959	normal	0.010305868	-0.395900556	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K10203|0|ptr:461436|ELOVL6; ELOVL fatty acid elongase 6; K10203 elongation of very long chain fatty acids protein 6 [EC:2.3.1.199] (A)	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	GNS1/SUR4 family	Elongation of very long chain fatty acids protein 6 GN=ELOVL6 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: elongation of very long chain fatty acids protein 6 [Ursus maritimus] 
ENSG00000170523(KRT83)	--	0.21199	8	0.128399	5	0.0251918	0	0	0	0.154221	5	0.131233	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:3889|KRT83, HB3, Hb-3, KRTHB3; keratin 83; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cuticular Hb3 GN=KRT83 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: keratin, type II microfibrillar, component 7C [Felis catus]"
ENSG00000170525(PFKFB3)	--	150.4220199	12181	152.6750671	13405	123.1686246	10796	140.3202495	12208	145.4754194	12557	146.1965812	11590	0.996793171	-0.027634491	normal	0.995861109	-0.115692458	normal	0.995868951	0.094079521	normal	0.949356766	-0.022700275	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: 6-phosphofructo-2-kinase activity (GO:0003873);; Molecular Function: ATP binding (GO:0005524);; Biological Process: fructose metabolic process (GO:0006000);; 	"K01103|0|pps:100995244|PFKFB3; 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; K01103 6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3  [EC:2.7.1.105 3.1.3.46] (A)"	Fructose and mannose metabolism (ko00051);; HIF-1 signaling pathway (ko04066);; AMPK signaling pathway (ko04152)	[G]	Carbohydrate transport and metabolism	6-phosphofructo-2-kinase;; Histidine phosphatase superfamily (branch 1);; AAA domain;; Chromatin associated protein KTI12	"Fructose-2,6-bisphosphatase GN=PFKFB3 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 isoform X2 [Tupaia chinensis]"
ENSG00000170537(TMC7)	--	1.915600373	138	2.280073	161	2.183841875	158	4.861748	336	6.122745	412	5.646614	401	4.94E-07	1.243808751	up	1.41E-08	1.326093699	up	1.10E-08	1.327128696	up	4.22E-10	1.309571303	up	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 7 GN=TMC7 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane channel-like protein 7 isoform X1 [Felis catus]
ENSG00000170542(SERPINB9)	--	3.922563	250	2.3735324	150	2.814854	178	8.726348	558	7.35301	468	5.72883	367	4.64E-07	1.12276878	up	5.84E-13	1.610442981	up	5.01E-05	1.029390618	up	8.17E-05	1.246522367	up	--	--	--	"K13963|0|hsa:5272|SERPINB9, CAP-3, CAP3, PI-9, PI9; serpin peptidase inhibitor, clade B (ovalbumin), member 9; K13963 serpin B (A)"	Amoebiasis (ko05146)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B9 GN=SERPINB9 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: serpin B9 [Ceratotherium simum simum]
ENSG00000170545(SMAGP)	--	4.518478	97	6.01316	101	6.299151	115	11.171626	263	11.451647	207	8.524139	190	1.10E-07	1.394234512	up	0.0021115	1.003144728	up	0.180153617	0.708749948	normal	9.77E-05	1.05432684	up	--	--	--	--	--	--	--	--	Small cell adhesion glycoprotein GN=SMAGP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: small cell adhesion glycoprotein isoform X1 [Mustela putorius furo] 
ENSG00000170558(CDH2)	--	16.45342147	1331	18.04091877	1457	17.58960847	1417	49.77635733	3971	51.14528558	4110	47.00436975	3738	0	1.545076913	up	2.22E-16	1.473760089	up	5.22E-15	1.39018613	up	6.33E-29	1.469607759	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06736|0|hsa:1000|CDH2, CD325, CDHN, CDw325, NCAD; cadherin 2, type 1, N-cadherin (neuronal); K06736 cadherin 2, type 1, N-cadherin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin prodomain like	Cadherin-2 (Precursor) GN=CDH2 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: cadherin-2 [Mustela putorius furo]
ENSG00000170561(IRX2)	--	0.0197443	1	0.055335958	2	0	0	1.370793	60	1.28738	57	0.737856423	38	5.81E-12	4.579463251	up	2.48E-10	4.041726182	up	6.42E-08	4.703514922	up	5.19E-15	5.665861413	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Iroquois-class homeodomain protein IRX-2 GN=IRX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: iroquois-class homeodomain protein IRX-2 [Loxodonta africana] 
ENSG00000170571(EMB)	--	15.03973	853	16.347445	956	15.340451	876	11.114344	656	10.78289818	596	9.07967661	515	0.690007786	-0.408839669	normal	0.009749136	-0.70170514	normal	0.00161389	-0.772888815	normal	9.12E-05	-0.625608525	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin C1-set domain	Embigin (Precursor) GN=EMB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: embigin [Camelus dromedarius]
ENSG00000170577(SIX2)	--	0.0593991	2	0	0	0.0841003	2	0.0293627	1	0	0	0.0582191	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox domain;; Homeobox KN domain	Homeobox protein SIX2 GN=SIX2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox protein SIX2 [Camelus dromedarius]
ENSG00000170579(DLGAP1)	--	0.01515445	1	0.01053908	1	0	0	0	0	0.020013728	1	0.026330064	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signaling (GO:0023052);; 	"K15008|0|pps:100980648|DLGAP1; discs, large (Drosophila) homolog-associated protein 1; K15008 discs, large-associated protein 1 (A)"	Glutamatergic synapse (ko04724)	[T]	Signal transduction mechanisms	Guanylate-kinase-associated protein (GKAP) protein	Disks large-associated protein 1 GN=DLGAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: disks large-associated protein 1 isoform 2 [Ceratotherium simum simum]
ENSG00000170581(STAT2)	--	5.376182902	486	4.47085234	406	5.8547457	517	6.58009586	603	7.140026722	633	10.138536	915	0.908675167	0.279574726	normal	0.084040596	0.617443271	normal	0.000533013	0.813503534	normal	0.093088739	0.59069927	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K11221|0|hsa:6773|STAT2, ISGF-3, P113, STAT113; signal transducer and activator of transcription 2, 113kDa; K11221 signal transducer and activator of transcription 2 (A)"	Chemokine signaling pathway (ko04062);; Osteoclast differentiation (ko04380);; Jak-STAT signaling pathway (ko04630);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[KT]	Transcription;; Signal transduction mechanisms	"STAT protein, DNA binding domain;; STAT protein, all-alpha domain;; STAT protein, protein interaction domain;; Signal transducer and activator of transcription 2 C terminal;; SH2 domain"	Signal transducer and activator of transcription 2 GN=STAT2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: signal transducer and activator of transcription 2 [Galeopterus variegatus]
ENSG00000170584(NUDCD2)	--	6.625185172	538	6.815460477	630	6.673135793	604	7.505269338	657	6.186459	561	7.151222196	614	0.924840671	0.256790457	normal	0.95291822	-0.188298295	normal	0.973822805	0.015360519	normal	0.941803782	0.026608337	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	CS domain	NudC domain-containing protein 2 GN=NUDCD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nudC domain-containing protein 2 [Canis lupus familiaris]
ENSG00000170604(IRF2BP1)	--	28.5939	1243	26.0529	1169	26.2078	1199	24.4952	1075	29.4037	1285	25.7058	1133	0.94670771	-0.240002541	normal	0.976474871	0.114925033	normal	0.97837777	-0.089858629	normal	0.785695034	-0.068884292	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Interferon regulatory factor 2-binding protein zinc finger;; Zinc finger, C3HC4 type (RING finger)"	Interferon regulatory factor 2-binding protein 1 GN=IRF2BP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: interferon regulatory factor 2-binding protein 1 [Camelus bactrianus]
ENSG00000170606(HSPA4)	--	95.45388151	6776	98.47952107	7174	106.8846331	7523	99.77042042	7636	93.64461877	7179	81.99725005	6120	0.992555601	0.141520725	normal	0.994857672	-0.020417103	normal	0.964209384	-0.305999552	normal	0.830963033	-0.058308536	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	"K09489|0|hsa:3308|HSPA4, APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY; heat shock 70kDa protein 4; K09489 heat shock 70kDa protein 4 (A)"	Antigen processing and presentation (ko04612)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein	Heat shock 70 kDa protein 4 GN=HSPA4 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 4 [Physeter catodon]
ENSG00000170608(FOXA3)	--	1.111391806	38	0.480858	17	0.686248	23	1.391940002	46	1.483225868	50	0.7276681	25	0.97644727	0.23611577	normal	0.06436665	1.45619665	normal	0.986703176	0.105356831	normal	0.377810787	0.610723579	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transcription factor binding (GO:0008134);; Molecular Function: protein domain specific binding (GO:0019904);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08038|1.20323e-155|ptr:456143|FOXA3; forkhead box A3; K08038 forkhead box protein A3, hepatocyte nuclear factor 3-gamma (A)"	Maturity onset diabetes of the young (ko04950)	[K]	Transcription	Fork head domain;; Forkhead N-terminal region;; HNF3 C-terminal domain	Hepatocyte nuclear factor 3-gamma GN=FOXA3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: hepatocyte nuclear factor 3-gamma [Erinaceus europaeus]
ENSG00000170619(COMMD5)	--	23.78703732	448	22.681858	454	22.05568536	463	25.553443	486	26.04415529	497	24.509919	493	0.967589025	0.086340985	normal	0.964855827	0.108780602	normal	0.968297726	0.082024342	normal	0.764023799	0.091702692	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 5 GN=COMMD5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COMM domain-containing protein 5 [Galeopterus variegatus]
ENSG00000170624(SGCD)	--	1.3119989	102	1.252152766	151	1.3244994	91	13.85908777	1591	14.76648485	1522	9.357774918	1042	0	3.912526735	up	0	3.299094036	up	0	3.487441102	up	2.19E-20	3.571402059	up	--	--	Cellular Component: sarcoglycan complex (GO:0016012);; Cellular Component: integral component of membrane (GO:0016021);; 	"K12563|0|ptr:462216|SGCD; sarcoglycan, delta (35kDa dystrophin-associated glycoprotein); K12563 delta-sarcoglycan (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	[Z]	Cytoskeleton	Sarcoglycan complex subunit protein	Delta-sarcoglycan GN=SGCD OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: delta-sarcoglycan [Vicugna pacos]
ENSG00000170627(GTSF1)	--	0.08791186	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	U11-48K-like CHHC zinc finger	Gametocyte-specific factor 1 GN=GTSF1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: gametocyte-specific factor 1 isoform X1 [Mustela putorius furo] 
ENSG00000170631(ZNF16)	--	2.682322671	141	2.62791031	141	1.9822757	104	2.374886	126	2.04888312	110	2.13798232	114	0.956459753	-0.19090161	normal	0.896165107	-0.375051208	normal	0.966230561	0.122457559	normal	0.747209522	-0.163302018	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal"	Zinc finger protein 16 GN=ZNF16 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 16 [Galeopterus variegatus]
ENSG00000170632(ARMC10)	--	26.41867201	906	25.999354	908	28.344705	951	31.35162712	1075	30.27066994	991	30.076367	1029	0.953058564	0.215585504	normal	0.973975946	0.104599413	normal	0.974995274	0.105273322	normal	0.517734466	0.141394665	normal	--	--	--	--	--	--	--	Armadillo-like;; V-ATPase subunit H	Armadillo repeat-containing protein 10 GN=ARMC10 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing protein 10 [Ceratotherium simum simum]
ENSG00000170633(RNF34)	--	15.71217494	601	17.00314413	657	18.0148648	688	18.875343	725	19.002158	675	19.24503623	714	0.935760053	0.239226295	normal	0.974120581	0.017527771	normal	0.974651591	0.045126694	normal	0.712441068	0.098344631	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Degradation arginine-rich protein for mis-folding"	E3 ubiquitin-protein ligase RNF34 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF34 [Tupaia chinensis]
ENSG00000170634(ACYP2)	--	8.025858752	86	9.310549537	102	7.727561885	89	6.216725677	73	7.025347319	78	7.34869399	85	0.95845814	-0.262181603	normal	0.911594167	-0.401618582	normal	0.971190853	-0.073358308	normal	0.639479246	-0.251957263	normal	[C]	Energy production and conversion	--	"K01512|5.29222e-81|ptr:459231|ACYP2; acylphosphatase 2, muscle type; K01512 acylphosphatase [EC:3.6.1.7] (A)"	Pyruvate metabolism (ko00620)	[C]	Energy production and conversion	Acylphosphatase	Acylphosphatase-2 GN=ACYP2 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: acylphosphatase-2 [Camelus ferus]
ENSG00000170638(TRABD)	--	20.11930934	851	19.0501582	820	20.97877681	910	20.18923349	856	20.4239811	856	18.2045065	767	0.977506876	-0.022340383	normal	0.976328664	0.040487247	normal	0.932216668	-0.254470183	normal	0.761457182	-0.079496221	normal	[S]	Function unknown	--	--	--	[T]	Signal transduction mechanisms	TraB family	TraB domain-containing protein GN=TRABD OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: traB domain-containing protein isoform X3 [Equus caballus]
ENSG00000170667(RASA4B)	--	0.519792581	26	0.327820173	18	0.245085006	12	0.059317521	3	0.406881925	20	0.078796521	4	0.013327276	-2.626459099	normal	0.988211803	0.120934917	normal	--	--	--	--	--	--	--	--	Biological Process: intracellular signal transduction (GO:0035556);; Biological Process: regulation of GTPase activity (GO:0043087);; 	K17630|0|hsa:100271927|RASA4B; RAS p21 protein activator 4B; K17630 Ras GTPase-activating protein 4 (A)	Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; C2 domain;; BTK motif;; PH domain	Putative Ras GTPase-activating protein 4B GN=RASA4B OS=Homo sapiens (Human) PE=5 SV=2	T	Signal transduction mechanisms	PREDICTED: putative Ras GTPase-activating protein 4B isoform X1 [Galeopterus variegatus]
ENSG00000170677(SOCS6)	--	33.07259205	2034	31.20139608	1931	27.70783878	1744	23.95704421	1694	31.96398243	2128	25.41444823	1804	0.928168015	-0.29447391	normal	0.982570786	0.118634901	normal	0.985299648	0.040473348	normal	0.876113984	-0.04224621	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	"K10322|0|hsa:9306|SOCS6, CIS-4, CIS4, HSPC060, SOCS-4, SOCS-6, SOCS4, SSI4, STAI4, STATI4; suppressor of cytokine signaling 6; K10322 suppressor of cytokine signaling 6 (A)"	Prolactin signaling pathway (ko04917)	[T]	Signal transduction mechanisms	SOCS box;; SH2 domain	Suppressor of cytokine signaling 6 GN=SOCS6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: suppressor of cytokine signaling 6 [Ursus maritimus]
ENSG00000170681(MURC)	--	0.409477	20	0.285	14	0.345706	16	0.545496	27	0.297884	14	0.628412	31	0.982112154	0.377122645	normal	--	--	--	0.911646663	0.884876909	normal	0.545132023	0.505050604	normal	--	--	--	--	--	--	--	PTRF/SDPR family	Muscle-related coiled-coil protein GN=MURC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: muscle-related coiled-coil protein [Mustela putorius furo] 
ENSG00000170684(ZNF296)	--	4.361546319	136	3.066834751	96	3.676055784	118	2.348854663	73	2.891741771	90	1.960766868	62	0.047152722	-0.914138036	normal	0.967434026	-0.112701926	normal	0.081286571	-0.920191578	normal	0.085741484	-0.658810711	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 296 GN=ZNF296 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 296 [Galeopterus variegatus]
ENSG00000170703(TTLL6)	--	0.721017442	47	0.631438097	45	0.3742624	29	1.073986379	76	1.804004399	135	1.647227766	135	0.806507679	0.64576702	normal	8.61E-06	1.532387443	up	2.54E-10	2.153528499	up	0.001721983	1.495526121	up	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16582|0|hsa:284076|TTLL6, TTL.6; tubulin tyrosine ligase-like family, member 6; K16582 tubulin polyglutamylase TTLL6/13 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin polyglutamylase TTLL6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: tubulin polyglutamylase TTLL6 [Physeter catodon]
ENSG00000170734(POLH)	--	6.393220673	408	8.686808729	554	8.438387	535	7.866775	502	5.787542309	368	8.097007798	520	0.91642604	0.267376945	normal	0.107412585	-0.609550029	normal	0.971316968	-0.049177702	normal	0.736046919	-0.128076549	normal	[L]	"Replication, recombination and repair"	Molecular Function: damaged DNA binding (GO:0003684);; Biological Process: DNA repair (GO:0006281);; 	"K03509|0|pps:100981423|POLH; polymerase (DNA directed), eta; K03509 DNA polymerase eta [EC:2.7.7.7] (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	impB/mucB/samB family;; impB/mucB/samB family C-terminal domain	DNA polymerase eta GN=POLH OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase eta [Myotis lucifugus]
ENSG00000170743(SYT9)	--	0.503953	40	0.201603	16	0.748057	59	0.326603	26	0.0977305	7	0.224543	18	0.941434524	-0.622436825	normal	--	--	--	0.004691082	-1.640711703	down	0.276476376	-1.194548019	normal	[R]	General function prediction only	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-9 GN=SYT9 OS=Homo sapiens (Human) PE=2 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-9 isoform X1 [Oryctolagus cuniculus]
ENSG00000170745(KCNS3)	--	4.001221097	159	2.4461759	98	2.419165398	96	2.295180534	91	2.936243936	114	1.945312948	73	0.075913535	-0.825235822	normal	0.958552873	0.193976245	normal	0.921976382	-0.396248673	normal	0.51196042	-0.366575022	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04933|0|hsa:3790|KCNS3, KV9.3; potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3; K04933 potassium voltage-gated channel delayed-rectifier subfamily S member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily S member 3 GN=KCNS3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily S member 3 [Felis catus] 
ENSG00000170759(KIF5B)	--	55.6526	5964	59.1195	6322	60.4696	6369	55.0042	5932	51.0969	5483	50.5295	5423	0.994112444	-0.038583957	normal	0.983209212	-0.226783809	normal	0.980857598	-0.240205262	normal	0.403410084	-0.169267559	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10396|0|hsa:3799|KIF5B, HEL-S-61, KINH, KNS, KNS1, UKHC; kinesin family member 5B; K10396 kinesin family member 5 (A)"	Dopaminergic synapse (ko04728)	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-1 heavy chain GN=KIF5B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: kinesin-1 heavy chain [Galeopterus variegatus]
ENSG00000170775(GPR37)	--	2.74046	144	3.9252	208	2.6453	140	1.65907	87	2.17067	114	3.63425	192	0.228993635	-0.747438909	normal	0.013908835	-0.880197496	normal	0.794320967	0.443283106	normal	0.608513742	-0.343437952	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04243|0|ggo:101152904|GPR37; probable G-protein coupled receptor 37; K04243 G protein-coupled receptor 37 (endothelin receptor type B-like) (A)	Parkinson's disease (ko05012)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Prosaposin receptor GPR37 (Precursor) GN=GPR37 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 37 [Ceratotherium simum simum]
ENSG00000170776(AKAP13)	--	11.19123371	2709	12.94580998	3514	13.46013698	2868	14.61709827	3720	16.40450203	3937	17.15075565	4256	0.721784023	0.426502794	normal	0.98722164	0.142498004	normal	0.15557492	0.560917357	normal	0.019152117	0.369047732	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K16529|0|pps:100991641|AKAP13; A kinase (PRKA) anchor protein 13; K16529 A-kinase anchor protein 13 (A)	--	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; RII binding domain	A-kinase anchor protein 13 GN=AKAP13 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: A-kinase anchor protein 13 [Loxodonta africana]
ENSG00000170779(CDCA4)	--	23.68158232	971	24.6341119	1029	25.50253814	1057	27.10372611	1117	23.38252308	957	24.38341401	1004	0.966199457	0.171001304	normal	0.972336063	-0.125886809	normal	0.97735114	-0.082386589	normal	0.976131828	-0.011606511	normal	--	--	--	--	--	--	--	SERTA motif	Cell division cycle-associated protein 4 GN=CDCA4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cell division cycle-associated protein 4 [Galeopterus variegatus]
ENSG00000170786(SDR16C5)	--	0.546634964	15	0.288063029	8	0.134078068	4	0.188251183	7	0.49842543	14	0.253724448	8	--	--	--	--	--	--	--	--	--	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K15734|0|ptr:472773|SDR16C5; short chain dehydrogenase/reductase family 16C, member 5; K15734 all-trans-retinol dehydrogenase (NAD+) [EC:1.1.1.105] (A)"	Retinol metabolism (ko00830)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase	Epidermal retinol dehydrogenase 2 GN=SDR16C5 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: epidermal retinol dehydrogenase 2 isoform X1 [Physeter catodon]
ENSG00000170788(DYDC1)	--	0	0	0	0	0	0	0.234383026	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Dpy-30 motif	DPY30 domain-containing protein 1 GN=DYDC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DPY30 domain-containing protein 1 isoform X1 [Canis lupus familiaris] 
ENSG00000170790(OR10A2)	--	0	0	0.164787	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:341276|OR10A2, OR10A2P, OR11-82, OR11-86, OST363; olfactory receptor, family 10, subfamily A, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 10A2 GN=OR10A2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 10A5-like [Equus caballus] 
ENSG00000170791(CHCHD7)	--	9.17734979	199	10.84062964	199	9.672298	192	10.2967645	232	13.66130788	267	9.364063084	164	0.950390075	0.189170493	normal	0.806791159	0.400012036	normal	0.94227696	-0.233708014	normal	0.709106598	0.146260665	normal	--	--	--	--	--	[S]	Function unknown	--	Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 GN=CHCHD7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil-helix-coiled-coil-helix domain-containing protein 7 [Vicugna pacos]
ENSG00000170801(HTRA3)	--	0.700607	26	0.528347	21	0.920809	35	0.2807238	12	0.691242	29	0.282108	11	0.897072156	-1.05271467	normal	0.977281706	0.418501804	normal	0.220954299	-1.552655147	normal	0.358143367	-0.677179131	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: regulation of cell growth (GO:0001558);; Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Molecular Function: insulin-like growth factor binding (GO:0005520);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; 	K08785|0|ggo:101151165|HTRA3; serine protease HTRA3 isoform 1; K08785 HtrA serine peptidase 3 [EC:3.4.21.-] (A)	--	--	--	Trypsin-like peptidase domain;; Trypsin;; PDZ domain;; Kazal-type serine protease inhibitor domain;; PDZ domain (Also known as DHR or GLGF);; Kazal-type serine protease inhibitor domain;; Peptidase S46	Serine protease HTRA3 (Precursor) GN=HTRA3 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: serine protease HTRA3 [Bubalus bubalis]
ENSG00000170802(FOXN2)	--	10.80808854	793	11.29090625	813	10.82498669	762	6.480208209	496	6.893982708	520	7.275359181	546	0.009001338	-0.706065998	normal	0.025885318	-0.664610817	normal	0.408543391	-0.488031811	normal	0.000171988	-0.621265029	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09407|0|ptr:459220|FOXN2, HTLF; forkhead box N2; K09407 forkhead box protein N (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein N2 GN=FOXN2 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: forkhead box protein N2-like [Canis lupus familiaris]
ENSG00000170832(USP32)	--	20.8355022	2531	22.82515866	2739	20.89803847	2456	16.68545119	1964	16.88264977	1981	22.40804309	2581	0.778718477	-0.396470771	normal	0.443640615	-0.488528269	normal	0.987949501	0.06329012	normal	0.172306456	-0.264048853	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-specific protease activity (GO:0004843);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11837|0|hsa:84669|USP32, NY-REN-60, USP10; ubiquitin specific peptidase 32 (EC:3.4.19.12); K11837 ubiquitin carboxyl-terminal hydrolase 6/32 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; DUSP domain;; Ubiquitin carboxyl-terminal hydrolase;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF hand;; Ubiquitin-like domain	Ubiquitin carboxyl-terminal hydrolase 32 (Precursor) GN=USP32 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 32 [Camelus bactrianus]
ENSG00000170835(CEL)	--	0.4568765	25	0.316531557	15	0.225729	11	0.355589	19	0.44503386	21	0.423658692	24	0.982526497	-0.398574625	normal	0.983931825	0.427447027	normal	0.924218451	1.020302065	normal	0.759741595	0.306270648	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K12298|0|hsa:1056|CEL, BAL, BSDL, BSSL, CELL, CEase, FAP, FAPP, LIPA, MODY8; carboxyl ester lipase (EC:3.1.1.13 3.1.1.3); K12298 bile salt-stimulated lipase [EC:3.1.1.3 3.1.1.13] (A)"	Steroid biosynthesis (ko00100);; Glycerolipid metabolism (ko00561);; Pancreatic secretion (ko04972);; Fat digestion and absorption (ko04975)	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	Bile salt-activated lipase (Precursor) GN=CEL OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: bile salt-activated lipase isoform 1 [Canis lupus familiaris]
ENSG00000170836(PPM1D)	--	6.720739	360	8.897224396	495	9.5037715	437	7.330992	446	7.513249	509	12.731152	718	0.910298312	0.277150235	normal	0.970936379	0.018754072	normal	0.010853486	0.706133623	normal	0.412971954	0.35304496	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K10147|0|hsa:8493|PPM1D, PP2C-DELTA, WIP1; protein phosphatase, Mg2+/Mn2+ dependent, 1D (EC:3.1.3.16); K10147 protein phosphatase 1D [EC:3.1.3.16] (A)"	p53 signaling pathway (ko04115)	[T]	Signal transduction mechanisms	Protein phosphatase 2C;; Protein phosphatase 2C	Protein phosphatase 1D GN=PPM1D OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1D [Felis catus]
ENSG00000170837(GPR27)	--	4.31444	135	4.87472	156	3.26854	104	2.64165	83	3.16251	99	2.61049	82	0.322806112	-0.72201914	normal	0.367532724	-0.669255002	normal	0.933412292	-0.345507577	normal	0.100833551	-0.603038116	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04301|5.82279e-145|pon:100462320|GPR27; G protein-coupled receptor 27; K04301 G protein-coupled receptor 27 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Probable G-protein coupled receptor 27 GN=GPR27 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 27 [Orcinus orca]
ENSG00000170852(KBTBD2)	--	13.86166801	797	14.97477899	861	13.83794854	789	13.24327755	763	14.17289138	795	18.91155805	1049	0.972866155	-0.093544597	normal	0.96833255	-0.136235825	normal	0.712918947	0.401955701	normal	0.838628801	0.071029422	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10470|0|nle:100606893|KBTBD2; kelch repeat and BTB (POZ) domain containing 2; K10470 kelch repeat and BTB domain-containing protein 2 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"BTB/POZ domain;; BTB And C-terminal Kelch;; Kelch motif;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain"	Kelch repeat and BTB domain-containing protein 2 GN=KBTBD2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch repeat and BTB domain-containing protein 2 [Equus caballus] 
ENSG00000170854(RIOX2)	--	15.420565	831	14.17223773	822	14.753928	850	18.554111	941	15.737583	852	19.59290664	1037	0.967837123	0.148256284	normal	0.976604363	0.030233844	normal	0.919381242	0.27814099	normal	0.474005542	0.156250515	normal	--	--	--	--	--	[S]	Function unknown	Cupin superfamily protein;; Cupin-like domain	Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA isoform X1 [Galeopterus variegatus]
ENSG00000170855(TRIAP1)	--	39.6128	634	42.1184	690	43.0755	696	55.9338	925	51.7878	823	58.8015	951	0.295768167	0.51310341	normal	0.94128941	0.232402627	normal	0.579737679	0.441243199	normal	0.021111484	0.396982712	normal	--	--	--	K17968|1.82218e-50|ptr:742486|TRIAP1; TP53 regulated inhibitor of apoptosis 1; K17968 TRIAP1/MDM35 family protein (A)	--	[S]	Function unknown	Uncharacterised protein family (UPF0203)	TP53-regulated inhibitor of apoptosis 1 GN=TRIAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: TP53-regulated inhibitor of apoptosis 1 [Bubalus bubalis]
ENSG00000170860(LSM3)	--	9.61159	655	10.8938	743	11.9658	808	12.6767	868	10.8321	734	12.4298	847	0.780643437	0.374602432	normal	0.97484933	-0.038928986	normal	0.975983011	0.059606264	normal	0.583066321	0.129661688	normal	[K]	Transcription	--	"K12622|6.37016e-50|umr:103669509|LSM3; LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae); K12622 U6 snRNA-associated Sm-like protein LSm3 (A)"	RNA degradation (ko03018);; Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm3 GN=LSM3 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: U6 snRNA-associated Sm-like protein LSm3-like [Odobenus rosmarus divergens]
ENSG00000170871(KIAA0232)	--	9.213294735	1169	9.13784	1115	10.20856456	1110	10.1089349	1275	12.02901734	1354	9.669123127	1263	0.978568877	0.094271396	normal	0.939700653	0.258438967	normal	0.967070058	0.177776315	normal	0.368904478	0.176304321	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4603)	Uncharacterized protein KIAA0232 GN=KIAA0232 OS=Homo sapiens (Human) PE=1 SV=5	R	General function prediction only	PREDICTED: uncharacterized protein KIAA0232 homolog isoform X1 [Tupaia chinensis]
ENSG00000170873(MTSS1)	--	0.830258998	53	0.71881569	34	0.599376098	49	0.979016042	90	0.909291731	84	0.49798789	45	0.625125867	0.716986074	normal	0.01618549	1.247032563	normal	0.978009672	-0.127055012	normal	0.216028275	0.664672633	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: plasma membrane organization (GO:0007009);; 	--	--	--	--	IRSp53/MIM homology domain;; WH2 motif	Metastasis suppressor protein 1 GN=MTSS1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: metastasis suppressor protein 1 isoform X3 [Balaenoptera acutorostrata scammoni]
ENSG00000170876(TMEM43)	--	29.9287	1795	26.2448	1574	28.8312	1722	37.7755	2260	32.9254	1962	32.1411	1929	0.92590465	0.301276431	normal	0.926622744	0.296207596	normal	0.977713401	0.155347596	normal	0.141501688	0.251228689	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1625)	Transmembrane protein 43 GN=TMEM43 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 43 [Ailuropoda melanoleuca]
ENSG00000170881(RNF139)	--	26.45949404	952	21.910791	839	21.70442826	798	29.13999776	1053	28.375136	1053	28.76237	1066	0.974146291	0.114464002	normal	0.896683842	0.305843171	normal	0.692355183	0.408782837	normal	0.132824849	0.271673051	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K15703|0|hsa:11236|RNF139, HRCA1, RCA1, TRC8; ring finger protein 139; K15703 E3 ubiquitin-protein ligase RNF139 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"TRC8 N-terminal domain;; Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF139 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF139 [Mustela putorius furo]
ENSG00000170889(RPS9)	--	925.5552842	9969	936.5325046	10103	935.2270617	10013	965.0992367	10552	887.459378	9604	889.59925	9995	0.996144554	0.051155844	normal	0.995267432	-0.094488493	normal	0.99623449	-0.01088561	normal	0.95908328	-0.018232492	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Cellular Component: intracellular (GO:0005622);; Molecular Function: rRNA binding (GO:0019843);; 	K02997|4.3144e-121|tgu:100189936|40S ribosomal protein S9-like; K02997 small subunit ribosomal protein S9e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S4/S9 N-terminal domain;; S4 domain	40S ribosomal protein S9 GN=RPS9 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S9 [Elephantulus edwardii]
ENSG00000170892(TSEN34)	--	84.1871481	1924	72.95396428	1720	83.06878239	1958	65.50146793	1518	67.73942318	1548	65.47766282	1494	0.817516159	-0.372433521	normal	0.973043278	-0.173268974	normal	0.753964757	-0.398138906	normal	0.048067707	-0.317973944	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: tRNA-intron endonuclease activity (GO:0000213);; Biological Process: tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388);; "	K15323|0|pps:100982064|TSEN34; TSEN34 tRNA splicing endonuclease subunit; K15323 tRNA-splicing endonuclease subunit Sen34 [EC:3.1.27.9] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA intron endonuclease, catalytic C-terminal domain"	tRNA-splicing endonuclease subunit Sen34 GN=TSEN34 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-splicing endonuclease subunit Sen34 isoform X2 [Bubalus bubalis]
ENSG00000170899(GSTA4)	--	7.333019196	149	5.86270136	119	7.284850081	139	5.525785136	113	6.143019419	122	4.209148212	85	0.855611554	-0.424774103	normal	0.967884571	0.014313372	normal	0.342821287	-0.707893683	normal	0.360193717	-0.368724012	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K00799|4.61219e-161|pon:100450954|GSTA4; glutathione S-transferase alpha 4; K00799 glutathione S-transferase [EC:2.5.1.18] (A)	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Glutathione S-transferase A4 GN=GSTA4 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase A4 isoform X1 [Oryctolagus cuniculus]
ENSG00000170903(MSANTD4)	--	6.097310104	374	5.8533504	401	7.687984382	511	6.797088001	435	7.03920656	499	7.434899	472	0.950097794	0.186434228	normal	0.898337078	0.293018723	normal	0.964329162	-0.122450699	normal	0.721371218	0.108313357	normal	--	--	--	--	--	--	--	Myb/SANT-like DNA-binding domain	Myb/SANT-like DNA-binding domain-containing protein 4 GN=MSANTD4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: myb/SANT-like DNA-binding domain-containing protein 4 [Leptonychotes weddellii]
ENSG00000170906(NDUFA3)	--	56.0602165	350	54.929074	326	48.361937	353	61.641757	443	54.187658	334	58.247566	354	0.886093564	0.307915802	normal	0.967352215	0.013487767	normal	0.96885278	-0.00419233	normal	0.722315465	0.114457623	normal	--	--	--	"K03947|6.8901e-54|ptr:100614219|NDUFA3, CI-B9; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa; K03947 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 3 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	NADH dehydrogenase 1 alpha subcomplex subunit 3	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 GN=NDUFA3 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 [Galeopterus variegatus]
ENSG00000170909(OSCAR)	--	0.837518031	28	1.143214155	28	0.956526559	25	0.304719878	6	0.434154	13	0.406781764	13	0.103467021	-1.997425906	normal	0.871973272	-1.043802206	normal	0.944909589	-0.877009159	normal	0.034865094	-1.359066535	normal	--	--	--	"K14377|0|hsa:126014|OSCAR, PIGR3, PIgR-3; osteoclast associated, immunoglobulin-like receptor; K14377 osteoclast-associated immunoglobulin-like receptor (A)"	Osteoclast differentiation (ko04380)	--	--	Immunoglobulin domain	Osteoclast-associated immunoglobulin-like receptor (Precursor) GN=OSCAR OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: osteoclast-associated immunoglobulin-like receptor [Camelus dromedarius]
ENSG00000170917(NUDT6)	--	11.055992	179	13.85978	181	13.70455	186	15.9783	202	19.31705	250	18.299139	233	0.959022728	0.142412314	normal	0.748542158	0.44136191	normal	0.902350118	0.314447105	normal	0.342398274	0.306560758	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[T]	Signal transduction mechanisms	NUDIX domain	Nucleoside diphosphate-linked moiety X motif 6 GN=NUDT6 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: nucleoside diphosphate-linked moiety X motif 6 isoform X1 [Ursus maritimus]
ENSG00000170921(TANC2)	--	22.77545473	3434	30.242508	3333	22.827938	3194	29.68241855	4943	42.92565828	5827	22.27045251	4951	0.456432619	0.494479302	normal	0.000652979	0.784233001	normal	0.041153635	0.623825105	normal	8.57E-06	0.637138421	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Protein TANC2 GN=TANC2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein TANC2 isoform X2 [Equus caballus]
ENSG00000170946(DNAJC24)	--	7.69072	320	7.72825	342	8.41404	363	7.81509	353	8.49751	359	6.372343	304	0.962728369	0.110259861	normal	0.966810289	0.048352272	normal	0.920644179	-0.262990763	normal	0.93870179	-0.034151292	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K17867|3.34401e-107|ptr:737351|DNAJC24, DPH4, ZCSL3; DnaJ (Hsp40) homolog, subfamily C, member 24; K17867 diphthamide biosynthesis protein 4 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; CSL zinc finger	DnaJ homolog subfamily C member 24 GN=DNAJC24 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 24 [Leptonychotes weddellii]
ENSG00000170949(ZNF160)	--	9.206070429	594	9.476089693	687	7.550949316	544	6.501663833	401	4.863154104	364	8.43941471	525	0.112324685	-0.595804001	normal	5.07E-05	-0.934921193	normal	0.970950912	-0.059412534	normal	0.025058264	-0.521259567	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:90338|ZNF160, F11, HKr18, HZF5, KR18; zinc finger protein 160; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; CHY zinc finger;; NTF2 fold immunity protein;; TFIIH C1-like domain;; Rad4 beta-hairpin domain 2;; Transposase zinc-ribbon domain;; Rad4 beta-hairpin domain 1;; DNA directed RNA polymerase, 7 kDa subunit"	Zinc finger protein 160 GN=ZNF160 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 665-like isoform X1 [Galeopterus variegatus]
ENSG00000170955(PRKCDBP)	--	0	0	0	0	0	0	14.813444	276	12.799095	233	15.66522	287	0	7.481656306	up	0	7.266180335	up	0	7.571637442	up	2.42E-68	Inf	up	--	--	--	--	--	--	--	PTRF/SDPR family	Protein kinase C delta-binding protein GN=PRKCDBP OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein kinase C delta-binding protein [Odobenus rosmarus divergens]
ENSG00000170959(DCDC1)	--	0.102321042	4	0.136976521	6	0.339849014	9	0.117579235	11	0.354253651	31	0.2503547	20	--	--	--	0.038565245	2.094890411	normal	0.949349559	1.025680715	normal	--	--	--	--	--	--	--	--	--	--	Doublecortin;; Ricin-type beta-trefoil lectin domain	Doublecortin domain-containing protein 5 GN=DCDC5 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100517025 [Sus scrofa]
ENSG00000170961(HAS2)	--	3.544352	228	3.627092	230	3.177048	199	6.39072	416	7.26725	468	5.375825	347	0.002532413	0.832506449	normal	4.30E-05	0.99875207	normal	0.010277818	0.789276685	normal	1.60E-05	0.884024924	normal	[M]	Cell wall/membrane/envelope biogenesis	--	K00752|0|ptr:472850|HAS2; hyaluronan synthase 2; K00752 hyaluronan synthase [EC:2.4.1.212] (A)	--	[M]	Cell wall/membrane/envelope biogenesis	Glycosyltransferase like family 2;; Chitin synthase;; Glycosyl transferase family 2;; Glycosyl transferase family group 2	Hyaluronan synthase 2 GN=HAS2 OS=Homo sapiens (Human) PE=2 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: hyaluronan synthase 2 [Galeopterus variegatus]
ENSG00000170962(PDGFD)	--	7.604565836	494	8.730985192	564	6.928844278	442	6.465544043	421	8.283665192	541	10.1212858	659	0.92052398	-0.260643775	normal	0.969120934	-0.081270603	normal	0.166700282	0.56634351	normal	0.845091561	0.091742442	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	K05450|0|pps:100992738|PDGFD; platelet derived growth factor D; K05450 platelet derived growth factor C/D (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; Prostate cancer (ko05215);; Melanoma (ko05218);; Choline metabolism in cancer (ko05231)	--	--	CUB domain;; PDGF/VEGF domain	"Platelet-derived growth factor D, receptor-binding form (Precursor) GN=PDGFD OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	platelet-derived growth factor D [Oryctolagus cuniculus]
ENSG00000170965(PLAC1)	--	0.956661601	14	0.780681787	13	0.459857244	6	0.61059104	9	1.391345368	23	0.468868809	7	--	--	--	0.96672321	0.736581126	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Zona pellucida-like domain	Placenta-specific protein 1 (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: placenta-specific protein 1 [Panthera tigris altaica]
ENSG00000170967(DDI1)	--	0.0461684	2	0.0685237	3	0.0225643	0	0.045872	2	0.0668834	2	0.0228151	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; 	K11885|0|hsa:414301|DDI1; DNA-damage inducible 1 homolog 1 (S. cerevisiae); K11885 DNA damage-inducible protein 1 (A)	--	[L]	"Replication, recombination and repair"	Aspartyl protease;; Aspartyl protease;; Ubiquitin family;; Retroviral aspartyl protease;; Retroviral aspartyl protease	Protein DDI1 homolog 1 GN=DDI1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: protein DDI1 homolog 1 [Tupaia chinensis]
ENSG00000170989(S1PR1)	--	0.761274	36	0.602294306	29	0.593807	27	0.130431473	6	0.201772922	9	0.267820619	13	0.002742823	-2.343392364	down	0.404681477	-1.556668597	normal	0.909689775	-0.981948382	normal	0.004340949	-1.735401425	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04288|0|hsa:1901|S1PR1, CD363, CHEDG1, D1S3362, ECGF1, EDG-1, EDG1, S1P1; sphingosine-1-phosphate receptor 1; K04288 sphingosine 1-phosphate receptor 1 (A)"	FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Sphingosine 1-phosphate receptor 1 GN=S1PR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	sphingosine 1-phosphate receptor 1 [Oryctolagus cuniculus] 
ENSG00000171004(HS6ST2)	--	0.245645957	18	0.13533285	10	0.2157589	15	0.066379363	4	0.26610874	9	0.175134034	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	K08102|0|hsa:90161|HS6ST2; heparan sulfate 6-O-sulfotransferase 2 (EC:2.8.2.-); K08102 heparan sulfate 6-O-sulfotransferase HS6ST2 [EC:2.8.2.-] (A)	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	Sulfotransferase family	Heparan-sulfate 6-O-sulfotransferase 2 GN=HS6ST2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan-sulfate 6-O-sulfotransferase 2 isoform X3 [Canis lupus familiaris]
ENSG00000171016(PYGO1)	--	7.1359215	777	7.657177	867	7.3257754	826	7.14724975	819	7.853874	896	8.1746123	901	0.976086439	0.04502986	normal	0.977323437	0.025995578	normal	0.971955848	0.116888921	normal	0.82445739	0.061960528	normal	--	--	--	--	--	--	--	PHD-finger	Pygopus homolog 1 GN=PYGO1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: pygopus homolog 1 [Vicugna pacos]
ENSG00000171017(LRRC8E)	--	5.213227147	286	4.059122	235	3.310576135	225	4.98474352	230	3.156284	193	3.934520782	147	0.867626049	-0.343153079	normal	0.906802058	-0.303328606	normal	0.315493447	-0.617228558	normal	0.150253332	-0.410934308	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine-rich repeat containing protein 8;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat	Volume-regulated anion channel subunit LRRC8E GN=LRRC8E OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 8E [Odobenus rosmarus divergens]
ENSG00000171033(PKIA)	--	1.518027003	56	0.897816001	48	1.479622111	59	1.236383768	46	1.277419354	42	1.058762566	33	0.966982108	-0.305364248	normal	0.974724201	-0.207090743	normal	0.716217668	-0.818124186	normal	0.457997625	-0.451742301	normal	--	--	--	"K15985|1.1409e-46|ssc:397408|PKIA; protein kinase (cAMP-dependent, catalytic) inhibitor alpha; K15985 cAMP-dependent protein kinase inhibitor alpha (A)"	Alcoholism (ko05034)	--	--	cAMP-dependent protein kinase inhibitor	cAMP-dependent protein kinase inhibitor alpha GN=PKIA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cAMP-dependent protein kinase inhibitor alpha isoform X3 [Canis lupus familiaris]
ENSG00000171044(XKR6)	--	0	0	0	0	0	0	0	0	0	0	0.086759626	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	XK-related protein	XK-related protein 6 GN=XKR6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: XK-related protein 6 [Odobenus rosmarus divergens]
ENSG00000171045(TSNARE1)	--	4.30302147	387	5.0900132	541	4.116390069	404	2.906118671	342	4.081653542	397	5.143721343	488	0.943271666	-0.20828911	normal	0.544591013	-0.466387643	normal	0.919234084	0.263336269	normal	0.747188466	-0.138889579	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K13814|0|mcc:701269|TSNARE1; t-SNARE domain containing 1; K13814 t-SNARE domain-containing protein 1 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Myb/SANT-like DNA-binding domain;; Syntaxin-like protein;; SNARE domain	t-SNARE domain-containing protein 1 GN=TSNARE1 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: t-SNARE domain-containing protein 1 [Galeopterus variegatus]
ENSG00000171049(FPR2)	--	0.04294751	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04173|0|hsa:2358|FPR2, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH1, FPRH2, FPRL1, HM63, LXA4R; formyl peptide receptor 2; K04173 formyl peptide receptor-like (A)"	Neuroactive ligand-receptor interaction (ko04080);; Staphylococcus aureus infection (ko05150)	--	--	7 transmembrane receptor (rhodopsin family)	N-formyl peptide receptor 2 GN=FPR2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: N-formyl peptide receptor 2 [Canis lupus familiaris]
ENSG00000171051(FPR1)	--	0.098045547	3	0	0	0.031990172	0	0.228832303	5	0.441732618	9	0.226534583	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04172|0|hsa:2357|FPR1, FMLP, FPR; formyl peptide receptor 1; K04172 formyl peptide receptor 1 (A)"	Rap1 signaling pathway (ko04015);; Neuroactive ligand-receptor interaction (ko04080);; Staphylococcus aureus infection (ko05150)	--	--	7 transmembrane receptor (rhodopsin family)	fMet-Leu-Phe receptor GN=FPR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	fMet-Leu-Phe receptor [Oryctolagus cuniculus] 
ENSG00000171054(OR13H1)	--	0	0	0	0	0.338858	2	0	0	0	0	0.111947	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:347468|OR13H1, ORX1; olfactory receptor, family 13, subfamily H, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 13H1 GN=OR13H1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 13H1 [Ursus maritimus]
ENSG00000171055(FEZ2)	--	39.70579919	1349	34.74785023	1192	37.62195434	1291	34.43349056	1153	32.9706122	1141	23.34280619	789	0.940138672	-0.257013061	normal	0.978286364	-0.084402541	normal	0.004117958	-0.717596863	normal	0.117468711	-0.335893005	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	FEZ-like protein	Fasciculation and elongation protein zeta-2 GN=FEZ2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: fasciculation and elongation protein zeta-2 isoform X1 [Bubalus bubalis]
ENSG00000171056(SOX7)	--	12.50799863	377	8.502205549	283	8.560258342	294	13.9929351	429	11.4476384	372	8.680440667	275	0.957178343	0.154988466	normal	0.8185863	0.371338503	normal	0.962798397	-0.10412208	normal	0.723241561	0.151007024	normal	--	--	--	K09270|0|hsa:83595|SOX7; SRY (sex determining region Y)-box 7; K09270 transcription factor SOX7/8/10/18 (SOX group E/F) (A)	--	[K]	Transcription	Sox C-terminal transactivation domain;; HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-7 GN=SOX7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor SOX-7 [Chrysochloris asiatica]
ENSG00000171067(C11orf24)	--	24.625028	797	27.31529056	885	28.26988046	937	24.92171242	839	28.21105242	933	20.67784042	736	0.976449255	0.043177696	normal	0.976784792	0.05468206	normal	0.820635011	-0.355984808	normal	0.744757447	-0.083777497	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf24 (Precursor) GN=C11orf24 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C11orf24 homolog [Tupaia chinensis]
ENSG00000171094(ALK)	--	0.009280735	1	0.009153868	1	0	0	0.009332426	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K05119|0|hsa:238|ALK, CD246, NBLST3; anaplastic lymphoma receptor tyrosine kinase (EC:2.7.10.1); K05119 anaplastic lymphoma kinase [EC:2.7.10.1] (A)"	Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; MAM domain;; Glycine rich protein	ALK tyrosine kinase receptor (Precursor) GN=ALK OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ALK tyrosine kinase receptor [Felis catus]
ENSG00000171097(KYAT1)	--	7.8576106	292	6.50474868	248	7.458549	282	6.15382507	224	6.689828742	214	6.568427	223	0.774174961	-0.410825559	normal	0.936736005	-0.232627185	normal	0.867673117	-0.34485826	normal	0.233425462	-0.335595932	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00816|0|pps:100980672|CCBL1; cysteine conjugate-beta lyase, cytoplasmic; K00816 kynurenine---oxoglutarate transaminase / cysteine-S-conjugate beta-lyase / glutamine---phenylpyruvate transaminase [EC:2.6.1.7 4.4.1.13 2.6.1.64] (A)"	Tryptophan metabolism (ko00380);; Selenocompound metabolism (ko00450);; Chemical carcinogenesis (ko05204)	[E]	Amino acid transport and metabolism	Aminotransferase class I and II;; Cys/Met metabolism PLP-dependent enzyme	Kynurenine--oxoglutarate transaminase 1 GN=CCBL1 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: kynurenine--oxoglutarate transaminase 1 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000171100(MTM1)	--	4.850258897	262	4.989254196	269	4.526751452	237	4.19921699	229	4.409759588	238	3.798470705	206	0.940109342	-0.223647267	normal	0.946223247	-0.196893478	normal	0.945489717	-0.209101769	normal	0.522028729	-0.212157149	normal	--	--	--	K01108|0|pps:100995776|MTM1; myotubularin 1; K01108 phosphatidylinositol-3-phosphatase [EC:3.1.3.64] (A)	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[IU]	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	Myotubularin-like phosphatase domain;; GRAM domain;; Protein-tyrosine phosphatase	Myotubularin GN=MTM1 OS=Homo sapiens (Human) PE=1 SV=2	IU	"Lipid transport and metabolism;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: myotubularin isoform 1 [Odobenus rosmarus divergens]
ENSG00000171103(TRMT61B)	--	13.133074	409	15.160904	483	13.46681753	410	9.35486129	291	10.034272	318	9.442998	298	0.398656413	-0.519587485	normal	0.103599554	-0.622004249	normal	0.580960767	-0.466575591	normal	0.009219651	-0.542814357	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: tRNA (adenine-N1-)-methyltransferase activity (GO:0016429);; Biological Process: tRNA methylation (GO:0030488);; Cellular Component: tRNA (m1A) methyltransferase complex (GO:0031515);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	tRNA methyltransferase complex GCD14 subunit;; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);; Methyltransferase domain;; Methyltransferase domain	"tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial (Precursor) GN=TRMT61B OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial [Equus caballus] "
ENSG00000171105(INSR)	--	3.127078955	537	2.825169443	497	2.52999856	428	2.7261842	459	2.257620001	369	2.6919717	452	0.923342229	-0.256465487	normal	0.611634433	-0.449458006	normal	0.968377034	0.070179214	normal	0.387084035	-0.213444678	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);; Cellular Component: membrane (GO:0016020);; 	"K04527|0|hsa:3643|INSR, CD220, HHF5; insulin receptor (EC:2.7.10.1); K04527 insulin receptor [EC:2.7.10.1] (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adherens junction (ko04520);; Insulin signaling pathway (ko04910);; Ovarian steroidogenesis (ko04913);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Receptor L domain;; Protein kinase domain;; Furin-like cysteine rich region;; Fibronectin type III domain	Insulin receptor subunit beta (Precursor) GN=INSR OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: insulin receptor isoform X1 [Bison bison bison]
ENSG00000171109(MFN1)	--	13.58734826	892	12.25021377	848	11.79073141	771	12.38914179	815	12.08407225	819	10.16401125	683	0.965043329	-0.160786037	normal	0.974832146	-0.071497617	normal	0.957800721	-0.182755608	normal	0.55243967	-0.137866373	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: mitochondrial fusion (GO:0008053);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06030|0|hsa:55669|MFN1, hfzo1, hfzo2; mitofusin 1; K06030 mitofusin [EC:3.6.5.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	fzo-like conserved region;; Dynamin family;; 50S ribosome-binding GTPase	Mitofusin-1 GN=MFN1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitofusin-1 isoform X2 [Canis lupus familiaris] 
ENSG00000171116(HSFX1)	--	0.166272	6	0.164877	6	0.0809735	2	0.138376	5	0.296569	10	0.109642	4	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	HSF-type DNA-binding	"Heat shock transcription factor, X-linked GN=HSFX2 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: heat shock transcription factor, X-linked-like [Dasypus novemcinctus]"
ENSG00000171119(NRTN)	--	1.901358	30	1.033664	16	1.185294	17	0.804616	12	1.193077	18	0.5360089	10	0.714106115	-1.248501321	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	--	--	--	--	Transforming growth factor beta like domain	Neurturin (Precursor) GN=NRTN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neurturin-like isoform X1 [Mustela putorius furo] 
ENSG00000171121(KCNMB3)	--	1.661972	155	1.964748	184	1.305143	120	2.028798	174	1.584681019	141	1.638183	153	0.960994003	0.134725956	normal	0.847889566	-0.40165397	normal	0.912658041	0.338420091	normal	0.998020245	0.00572798	normal	--	--	Biological Process: potassium ion transport (GO:0006813);; Molecular Function: calcium-activated potassium channel activity (GO:0015269);; Cellular Component: membrane (GO:0016020);; 	"K04939|0|ptr:745901|KCNMB3; potassium large conductance calcium-activated channel, subfamily M beta member 3; K04939 potassium large conductance calcium-activated channel subfamily M beta member 3 (A)"	cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Insulin secretion (ko04911)	--	--	"Calcium-activated potassium channel, beta subunit"	Calcium-activated potassium channel subunit beta-3 GN=KCNMB3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: calcium-activated potassium channel subunit beta-3 [Galeopterus variegatus]
ENSG00000171124(FUT3)	--	0.028457911	1	0.190782955	3	0.027508156	0	0.028434405	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: fucosyltransferase activity (GO:0008417);; Cellular Component: membrane (GO:0016020);; 	"K00716|0|hsa:2525|FUT3, CD174, FT3B, FucT-III, LE, Les; fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) (EC:2.4.1.65); K00716 galactoside 3(4)-fucosyltransferase 3 [EC:2.4.1.65] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Glycosyltransferase family 10 (fucosyltransferase)	Galactoside 3(4)-L-fucosyltransferase GN=FUT3 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-(1,3)-fucosyltransferase 5-like [Galeopterus variegatus]"
ENSG00000171126(KCNG3)	--	1.47091	76	1.335312	70	1.507851	79	0.464017233	24	0.511449896	26	0.36242	19	0.000526027	-1.631915099	down	0.010769917	-1.398726203	normal	8.80E-06	-1.980628489	down	8.03E-05	-1.726848315	down	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04902|0|hsa:170850|KCNG3, KV10.1, KV6.3; potassium voltage-gated channel, subfamily G, member 3; K04902 potassium voltage-gated channel subfamily G member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily G member 3 GN=KCNG3 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily G member 3 isoform X1 [Condylura cristata]
ENSG00000171130(ATP6V0E2)	--	61.5901468	1334	54.6857788	1300	59.55967522	1365	61.051348	1515	55.85653	1280	76.24251231	1600	0.974399559	0.152561908	normal	0.981384418	-0.043743088	normal	0.959936514	0.220653495	normal	0.598083532	0.115192119	normal	--	--	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V0 domain (GO:0033179);; "	"K02153|5.5351e-132|hsa:155066|ATP6V0E2, ATP6V0E2L, C7orf32; ATPase, H+ transporting V0 subunit e2; K02153 V-type H+-transporting ATPase subunit e (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase subunit H	V-type proton ATPase subunit e 2 GN=ATP6V0E2 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit e 2 [Canis lupus familiaris]
ENSG00000171132(PRKCE)	--	4.989016	379	5.645819554	442	5.926468	474	4.705700468	420	4.156876074	368	7.344703	537	0.963044683	0.116908893	normal	0.905017019	-0.284697917	normal	0.955913271	0.171230027	normal	0.985247992	0.012773084	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K18050|0|pps:100974922|PRKCE; protein kinase C, epsilon; K18050 novel protein kinase C epsilon type [EC:2.7.11.13] (A)"	cGMP-PKG signaling pathway (ko04022);; Sphingolipid signaling pathway (ko04071);; Vascular smooth muscle contraction (ko04270);; Tight junction (ko04530);; Fc gamma R-mediated phagocytosis (ko04666);; Inflammatory mediator regulation of TRP channels (ko04750);; Type II diabetes mellitus (ko04930);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2 domain;; Protein kinase C terminal domain	Protein kinase C epsilon type GN=PRKCE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein kinase C epsilon type isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000171135(JAGN1)	--	36.506535	891	31.0461	776	28.4226	700	34.885231	859	33.722416	818	29.139287	711	0.975133773	-0.083452986	normal	0.975167001	0.054514154	normal	0.975496579	0.014172814	normal	0.985016047	-0.009261209	normal	--	--	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: endoplasmic reticulum organization (GO:0007029);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1352)	Protein jagunal homolog 1 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	protein jagunal homolog 1 [Bos taurus] 
ENSG00000171148(TADA3)	--	30.074149	1484	29.61776958	1461	30.8050209	1549	29.0136079	1423	29.86550785	1431	35.076981	1734	0.980933981	-0.091291159	normal	0.982439682	-0.051305402	normal	0.976323032	0.154332834	normal	0.982012688	0.009348561	normal	--	--	--	K11315|0|umr:103669573|TADA3; transcriptional adaptor 3; K11315 transcriptional adapter 3 (A)	--	[B]	Chromatin structure and dynamics	Histone acetyltransferases subunit 3	Transcriptional adapter 3 GN=TADA3 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: transcriptional adapter 3 isoform X5 [Mustela putorius furo] 
ENSG00000171150(SOCS5)	--	13.55210975	902	13.04004981	884	12.21480174	809	14.25919869	958	15.72405869	1047	13.7809375	922	0.977479377	0.055973441	normal	0.950157885	0.222366726	normal	0.961233528	0.180020181	normal	0.483652919	0.152276065	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	K04698|0|ptr:459209|SOCS5; suppressor of cytokine signaling 5; K04698 suppressor of cytokine signaling 5 (A)	Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917)	[T]	Signal transduction mechanisms	Suppressor of cytokine signalling;; SOCS box;; SH2 domain	Suppressor of cytokine signaling 5 GN=SOCS5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: suppressor of cytokine signaling 5 [Bos mutus] 
ENSG00000171155(C1GALT1C1)	--	24.92116053	592	23.69621759	568	23.3355108	551	21.06023664	506	21.71053503	512	21.71411625	516	0.92404589	-0.256570871	normal	0.956069201	-0.17069473	normal	0.967543274	-0.102681412	normal	0.465023311	-0.17874728	normal	--	--	--	K09653|0|ptr:465837|C1GALT1C1; C1GALT1-specific chaperone 1; K09653 C1GALT1-specific chaperone 1 [EC:2.4.1.-] (A)	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	--	C1GALT1-specific chaperone 1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: C1GALT1-specific chaperone 1 [Balaenoptera acutorostrata scammoni]
ENSG00000171159(C9orf16)	--	52.8337	485	44.688	427	44.7034	448	42.5219	425	53.2453	489	46.3799	451	0.939816942	-0.220606897	normal	0.953607107	0.173596982	normal	0.970815559	0.001332775	normal	0.972552315	-0.015664628	normal	--	--	--	--	--	--	--	Uncharacterised protein family (UPF0184)	UPF0184 protein C9orf16 GN=C9orf16 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0184 protein C9orf16 homolog [Orcinus orca] 
ENSG00000171160(MORN4)	--	11.304806	279	9.454338	251	9.519863	275	9.179753028	243	6.684988022	164	11.626298	255	0.937755983	-0.228789658	normal	0.240368564	-0.630679773	normal	0.961334219	-0.116559983	normal	0.300596271	-0.303279088	normal	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat	MORN repeat-containing protein 4 GN=MORN4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: MORN repeat-containing protein 4 isoformX2 [Canis lupus familiaris] 
ENSG00000171161(ZNF672)	--	17.29523	825	16.65773	803	17.33491864	852	18.646712	888	18.1278	862	19.05532	918	0.975418219	0.075198296	normal	0.974202586	0.080714593	normal	0.974086404	0.099179652	normal	0.74242841	0.084401955	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 672 GN=ZNF672 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 672 [Loxodonta africana]
ENSG00000171163(ZNF692)	--	9.286285484	347	9.859432817	377	7.081454745	297	7.441027723	269	7.586455816	264	9.40157091	323	0.779542363	-0.396163277	normal	0.389737814	-0.532884239	normal	0.962237603	0.112231668	normal	0.306790268	-0.275322632	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger protein 692 GN=ZNF692 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 692 isoform X1 [Sus scrofa] 
ENSG00000171169(NAIF1)	--	4.06252	249	3.85665	226	3.46301	211	3.110559	205	2.384047	152	2.92029	177	0.901911133	-0.309247107	normal	0.39774513	-0.588840131	normal	0.932000017	-0.259749696	normal	0.205203664	-0.383329489	normal	--	--	--	--	--	--	--	Myb/SANT-like DNA-binding domain	Nuclear apoptosis-inducing factor 1 GN=NAIF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear apoptosis-inducing factor 1 [Dasypus novemcinctus]
ENSG00000171174(RBKS)	--	5.355621	177	4.001627	133	5.838606001	195	5.54693	186	4.84471	159	6.07145	202	0.966607817	0.040379074	normal	0.944966372	0.233740594	normal	0.966358863	0.042267647	normal	0.844804995	0.094725652	normal	[G]	Carbohydrate transport and metabolism	--	K00852|0|ggo:101124527|RBKS; ribokinase isoform 1; K00852 ribokinase [EC:2.7.1.15] (A)	Pentose phosphate pathway (ko00030)	[G]	Carbohydrate transport and metabolism	pfkB family carbohydrate kinase;; Phosphomethylpyrimidine kinase	Ribokinase GN=RBKS OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: ribokinase isoform X1 [Ursus maritimus]
ENSG00000171195(MUC7)	--	0	0	0	0	0	0	0	0	0.043618663	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13909|8.61155e-68|hsa:4589|MUC7, MG2; mucin 7, secreted; K13909 mucin-7 (A)"	Salivary secretion (ko04970)	--	--	--	Mucin-7 (Precursor) GN=MUC7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mucin-7 [Camelus dromedarius]
ENSG00000171202(TMEM126A)	--	33.503478	281	35.621759	305	41.428291	347	33.640139	284	36.305055	304	39.37037	331	0.967438381	-0.015427559	normal	0.966650837	-0.026035176	normal	0.9659841	-0.076056465	normal	0.917939476	-0.042239178	normal	--	--	--	K18157|9.35467e-141|pps:100978373|TMEM126A; transmembrane protein 126A; K18157 transmembrane protein 126A (A)	--	--	--	Protein of unknown function (DUF1370)	Transmembrane protein 126A GN=TMEM126A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 126A isoform X2 [Canis lupus familiaris] 
ENSG00000171204(TMEM126B)	--	33.34996	494	38.465414	544	39.97586	523	39.0938	573	35.466488	493	39.590695	561	0.953482439	0.182663991	normal	0.95727766	-0.16296942	normal	0.968695052	0.092639697	normal	0.910190277	0.038417209	normal	--	--	--	K18165|2.10722e-169|pps:100977453|TMEM126B; transmembrane protein 126B; K18165 complex I assembly factor TMEM126B (A)	--	--	--	Protein of unknown function (DUF1370)	"Complex I assembly factor TMEM126B, mitochondrial GN=TMEM126B OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: complex I assembly factor TMEM126B, mitochondrial isoform X2 [Oryctolagus cuniculus]"
ENSG00000171206(TRIM8)	--	14.65962195	854	13.36613	802	14.56176449	879	22.074643	1312	19.914596	1197	18.981984	1145	0.079998744	0.587768444	normal	0.165630466	0.55545983	normal	0.791668339	0.372557921	normal	0.000971158	0.505995372	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K12001|0|hsa:81603|TRIM8, GERP, RNF27; tripartite motif containing 8; K12001 tripartite motif-containing protein 8 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	Probable E3 ubiquitin-protein ligase TRIM8 GN=TRIM8 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	probable E3 ubiquitin-protein ligase TRIM8 [Bos taurus] 
ENSG00000171208(NETO2)	--	50.383532	2786	52.537394	2908	47.5939	2650	50.74542759	2912	47.14942	2602	40.87764572	2301	0.989624026	0.032965052	normal	0.979671443	-0.18173289	normal	0.97259303	-0.211892933	normal	0.587616794	-0.116531519	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CUB domain;; Low-density lipoprotein receptor domain class A	Neuropilin and tolloid-like protein 2 (Precursor) GN=NETO2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuropilin and tolloid-like protein 2 isoform X1 [Mustela putorius furo]
ENSG00000171217(CLDN20)	--	0.318733	6	0.210042	4	0.781655	14	0.683247	13	0.464101	8	0.525124	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|2.35737e-160|ptr:472215|CLDN20; claudin 20; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family	Claudin-20 GN=CLDN20 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: claudin-20 [Leptonychotes weddellii]
ENSG00000171219(CDC42BPG)	--	0.555876289	72	0.29600635	40	0.414939879	55	1.1271265	146	1.039501429	134	0.737042866	98	0.018067292	0.974190095	normal	8.13E-07	1.685896594	up	0.365601719	0.808192581	normal	0.000963306	1.156325027	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K16307|0|hsa:55561|CDC42BPG, DMPK2, HSMDPKIN, KAPPA-200, MRCKG, MRCKgamma; CDC42 binding protein kinase gamma (DMPK-like) (EC:2.7.11.1); K16307 serine/threonine-protein kinase MRCK [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; CNH domain;; Protein tyrosine kinase;; DMPK coiled coil domain like;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Kinase-like;; PH domain;; Protein kinase C terminal domain	Serine/threonine-protein kinase MRCK gamma OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase MRCK gamma [Camelus bactrianus]
ENSG00000171222(SCAND1)	--	79.28129172	957	80.13233	978	80.39413157	1012	83.47213151	1037	92.12433166	1118	88.14709	1087	0.976674543	0.084861903	normal	0.965947308	0.171339321	normal	0.976672504	0.094714617	normal	0.60784187	0.1166962	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	SCAN domain	SCAN domain-containing protein 1 GN=SCAND1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: SCAN domain-containing protein 1 [Leptonychotes weddellii]
ENSG00000171223(JUNB)	--	27.0853	857	29.8289	953	24.077	787	64.4662	2036	77.9124	2485	46.5344	1494	7.75E-11	1.216081497	up	1.72E-13	1.359884815	up	1.16E-05	0.915155322	normal	0.000568984	1.189619556	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09028|3.03301e-171|pps:100982854|JUNB; jun B proto-oncogene; K09028 transcription factor jun-B (A)	Osteoclast differentiation (ko04380);; TNF signaling pathway (ko04668)	[K]	Transcription	Jun-like transcription factor;; bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Transcription factor jun-B GN=JUNB OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor jun-B [Canis lupus familiaris]
ENSG00000171224(C10orf35)	--	17.5083962	261	18.76006621	294	16.77118279	259	21.72969042	333	16.74979575	244	19.6539586	292	0.883881246	0.318974396	normal	0.908446723	-0.28872863	normal	0.954390889	0.163823463	normal	0.85524416	0.07244499	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4605)	Uncharacterized protein C10orf35 GN=C10orf35 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C10orf35 homolog isoform X1 [Tupaia chinensis] 
ENSG00000171227(TMEM37)	--	3.253601625	78	1.877319692	42	2.724233076	56	1.292501512	31	2.934640376	67	1.077522598	26	0.010872317	-1.319365186	normal	0.84689134	0.634122141	normal	0.359771466	-1.071748658	normal	0.525184117	-0.526319143	normal	--	--	Molecular Function: voltage-gated ion channel activity (GO:0005244);; Molecular Function: calcium channel activity (GO:0005262);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Voltage-dependent calcium channel gamma-like subunit protein family	Voltage-dependent calcium channel gamma-like subunit OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent calcium channel gamma-like subunit [Orycteropus afer afer]
ENSG00000171234(UGT2B7)	--	0.085407638	2	0	0	0	0	0.290451897	9	0.410214402	12	0.32305325	10	--	--	--	--	--	--	--	--	--	--	--	--	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00699|0|hsa:7364|UGT2B7, UDPGT_2B9, UDPGT2B7, UDPGTH2, UGT2B9; UDP glucuronosyltransferase 2 family, polypeptide B7 (EC:2.4.1.17); K00699 glucuronosyltransferase [EC:2.4.1.17] (A)"	Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Steroid hormone biosynthesis (ko00140);; Starch and sucrose metabolism (ko00500);; Retinol metabolism (ko00830);; Porphyrin and chlorophyll metabolism (ko00860);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain	UDP-glucuronosyltransferase 2B7 (Precursor) GN=UGT2B7 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronosyltransferase 2B4-like isoform X3 [Oryctolagus cuniculus]
ENSG00000171236(LRG1)	--	0.0173888	1	0	0	0	0	0.0693624	4	0.135349	7	0.120019	7	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Leucine-rich alpha-2-glycoprotein (Precursor) GN=LRG1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leucine-rich alpha-2-glycoprotein [Galeopterus variegatus]
ENSG00000171241(SHCBP1)	--	22.0267289	1313	21.51838	1328	23.52831286	1423	23.589673	1446	19.214836	1154	20.081561	1207	0.978991721	0.108247645	normal	0.955040619	-0.22376486	normal	0.947419658	-0.245517777	normal	0.598314011	-0.115940576	normal	--	--	--	--	--	--	--	Right handed beta helix region;; Periplasmic copper-binding protein (NosD);; Pectate lyase superfamily protein	SHC SH2 domain-binding protein 1 GN=SHCBP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SHC SH2 domain-binding protein 1 [Physeter catodon]
ENSG00000171243(SOSTDC1)	--	0.034085914	1	0.034458262	1	0	0	0.102559715	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular space (GO:0005615);; 	--	--	--	--	Sclerostin (SOST);; Cystine-knot domain;; DAN domain	Sclerostin domain-containing protein 1 (Precursor) GN=SOSTDC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_005669 [Ailuropoda melanoleuca]
ENSG00000171246(NPTX1)	--	7.539913	741	8.949848	899	8.33266789	832	4.480415833	446	8.662397	848	2.334382441	230	0.002765077	-0.761204062	normal	0.972773071	-0.105500642	normal	0	-1.856371536	down	0.219089649	-0.719814355	normal	--	--	--	--	--	--	--	Pentaxin family;; Concanavalin A-like lectin/glucanases superfamily	Neuronal pentraxin-1 (Precursor) GN=NPTX1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	neuronal pentraxin-1 precursor [Bos taurus] 
ENSG00000171262(FAM98B)	--	11.11339062	750	10.34721716	704	11.77784456	773	13.78832471	740	10.87681509	734	8.435361494	572	0.975073363	-0.050094273	normal	0.974529666	0.038696667	normal	0.585580794	-0.441736146	normal	0.543659476	-0.144052001	normal	--	--	--	"K15434|0|hsa:283742|FAM98B; family with sequence similarity 98, member B; K15434 protein FAM98B (A)"	--	[S]	Function unknown	Protein of unknown function (DUF2465)	Protein FAM98B GN=FAM98B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM98B [Tupaia chinensis]
ENSG00000171295(ZNF440)	--	0.14654473	12	0.243127803	19	0.171956234	13	0.02521924	2	0.036805623	2	0.012555086	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:126070|ZNF440; zinc finger protein 440; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 440 GN=ZNF440 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 709-like [Mustela putorius furo]
ENSG00000171298(GAA)	--	45.76763248	3179	39.720041	2814	40.59133123	2887	34.16160707	2375	43.166945	2960	40.529189	2701	0.606112272	-0.451224437	normal	0.989100024	0.051521292	normal	0.987174571	-0.104312406	normal	0.392561971	-0.164856801	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K12316|0|hsa:2548|GAA, LYAG; glucosidase, alpha; acid (EC:3.2.1.20); K12316 lysosomal alpha-glucosidase [EC:3.2.1.20] (A)"	Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 31;; Trefoil (P-type) domain;; Galactose mutarotase-like	70 kDa lysosomal alpha-glucosidase (Precursor) GN=GAA OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: lysosomal alpha-glucosidase [Galeopterus variegatus]
ENSG00000171302(CANT1)	--	76.4709495	3330	66.06890266	2856	71.39887255	2977	72.96809777	3066	72.55071648	3139	70.02871205	2825	0.985336175	-0.149924623	normal	0.986967263	0.114824482	normal	0.988451677	-0.083856061	normal	0.876307067	-0.042526661	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: nucleoside-diphosphatase activity (GO:0017110);; 	"K12304|0|hsa:124583|CANT1, DBQD, SCAN-1, SCAN1, SHAPY; calcium activated nucleotidase 1 (EC:3.6.1.6); K12304 soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Apyrase	Soluble calcium-activated nucleotidase 1 GN=CANT1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: soluble calcium-activated nucleotidase 1 [Galeopterus variegatus]
ENSG00000171303(KCNK3)	--	1.12108199	86	0.621212784	42	0.818370497	43	0.78894413	54	0.868021699	71	0.619395389	59	0.689283676	-0.686583865	normal	0.746901136	0.715971827	normal	0.947673939	0.434977487	normal	0.932686461	0.084394353	normal	--	--	--	"K04914|0|pon:100449819|KCNK3; potassium channel, subfamily K, member 3; K04914 potassium channel subfamily K member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 3 GN=KCNK3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 3 [Odobenus rosmarus divergens]
ENSG00000171307(ZDHHC16)	--	28.04435768	767	28.83859817	815	32.24486919	878	34.6772328	976	30.15804783	826	37.51651327	1062	0.880632341	0.316259586	normal	0.976726518	-0.002081	normal	0.928630014	0.265782644	normal	0.326329167	0.198540832	normal	[R]	General function prediction only	--	K18932|0|ggo:101150383|probable palmitoyltransferase ZDHHC16-like; K18932 palmitoyltransferase [EC:2.3.1.225] (A)	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC16 GN=ZDHHC16 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC16 isoform X1 [Tupaia chinensis]
ENSG00000171310(CHST11)	--	14.25848045	823	13.445688	730	16.42527388	837	31.085751	1775	36.09096	1849	32.342298	1339	2.97E-08	1.07662188	up	2.82E-12	1.317575054	up	0.013563345	0.668601324	normal	1.11E-06	1.032460067	up	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	K01017|0|mcf:102145281|CHST11; carbohydrate (chondroitin 4) sulfotransferase 11; K01017 chondroitin 4-sulfotransferase 11 [EC:2.8.2.5] (A)	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Sulfotransferase family	Carbohydrate sulfotransferase 11 GN=CHST11 OS=Homo sapiens (Human) PE=1 SV=1	MW	Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: carbohydrate sulfotransferase 11 isoform X1 [Tupaia chinensis]
ENSG00000171311(EXOSC1)	--	24.81355139	332	27.54713531	378	21.10222078	289	34.72076784	477	32.32247555	440	27.95835758	388	0.473069518	0.490072594	normal	0.946565778	0.196959818	normal	0.731718631	0.414815888	normal	0.109006295	0.36330831	normal	[J]	"Translation, ribosomal structure and biogenesis"	Cellular Component: exosome (RNase complex) (GO:0000178);; Molecular Function: RNA binding (GO:0003723);; 	K07573|1.06735e-142|mcc:706097|EXOSC1; exosome component 1; K07573 exosome complex component CSL4 (A)	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	Exosome component EXOSC1/CSL4;; Exosome complex exonuclease RRP4 N-terminal region	Exosome complex component CSL4 GN=EXOSC1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component CSL4 [Trichechus manatus latirostris] 
ENSG00000171314(PGAM1)	--	404.001	13179	386.521	12767	393.738	12991	455.313	14840	334.826	10869	354.507	11562	0.995721292	0.140402492	normal	0.987319589	-0.253594308	normal	0.993863264	-0.176391174	normal	0.749615964	-0.085163535	normal	[G]	Carbohydrate transport and metabolism	--	"K01834|7.74756e-179|cfa:477786|PGAM1; phosphoglycerate mutase 1 (brain); K01834 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [EC:5.4.2.11] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230);; Central carbon metabolism in cancer (ko05230)"	[G]	Carbohydrate transport and metabolism	Histidine phosphatase superfamily (branch 1)	Phosphoglycerate mutase 1 GN=PGAM1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: phosphoglycerate mutase 1 [Eptesicus fuscus]
ENSG00000171316(CHD7)	--	4.926244999	884	2.933426419	786	3.782684453	883	4.5750352	944	5.105673526	920	3.662487719	599	0.976887761	0.063800913	normal	0.953619036	0.205312564	normal	0.136557207	-0.566962331	normal	0.862951462	-0.074030825	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on acid anhydrides (GO:0016817);; "	K14437|0|ptr:464198|CHD7; chromodomain helicase DNA binding protein 7; K14437 chromodomain-helicase-DNA-binding protein 7 [EC:3.6.4.12] (A)	--	[K]	Transcription	"SNF2 family N-terminal domain;; BRK domain;; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Chromodomain-helicase-DNA-binding protein 7 GN=CHD7 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: chromodomain-helicase-DNA-binding protein 7 isoform X1 [Bubalus bubalis]
ENSG00000171320(ESCO2)	--	9.58936507	671	11.37147203	758	13.17566338	838	11.06769304	761	9.120298117	647	10.6666968	720	0.964363389	0.15042785	normal	0.931801127	-0.249319639	normal	0.944382219	-0.226802761	normal	0.652227183	-0.112444705	normal	--	--	--	"K11268|0|hsa:157570|ESCO2, 2410004I17Rik, EFO2, RBS; establishment of sister chromatid cohesion N-acetyltransferase 2 (EC:2.3.1.-); K11268 N-acetyltransferase [EC:2.3.1.-] (A)"	--	--	--	ESCO1/2 acetyl-transferase;; zinc-finger of acetyl-transferase ESCO	N-acetyltransferase ESCO2 GN=ESCO2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: N-acetyltransferase ESCO2 [Ceratotherium simum simum]
ENSG00000171345(KRT19)	--	101.4930231	2691	75.18141572	2001	105.6830866	2900	416.6183225	11023	386.9655039	10233	288.396037	7667	0	2.002858885	up	0	2.332142468	up	1.78E-15	1.393853215	up	1.39E-12	1.907911667	up	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3880|KRT19, CK19, K19, K1CS; keratin 19; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 19 GN=KRT19 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 19 [Tupaia chinensis]"
ENSG00000171346(KRT15)	--	0.350334638	19	0.457476073	16	0.336448271	15	1.747160609	92	1.108401154	68	0.393472459	23	1.79E-07	2.157914969	up	7.20E-05	1.968632243	up	0.978446901	0.56230914	normal	0.080023246	1.84705391	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3866|KRT15, CK15, K15, K1CO; keratin 15; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 15 GN=KRT15 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 15 [Camelus ferus] "
ENSG00000171357(LURAP1)	--	0.0629675	2	0	0	0	0	0	0	0.0308697	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Leucine rich adaptor protein	Leucine rich adaptor protein 1 GN=LURAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine rich adaptor protein 1 [Orcinus orca] 
ENSG00000171365(CLCN5)	--	2.6865546	410	4.0067997	656	3.4583235	494	2.759469781	403	3.049971898	415	4.013158192	552	0.96844312	-0.055466674	normal	0.024389188	-0.680021815	normal	0.960385755	0.151427048	normal	0.658860259	-0.207859664	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05012|0|pps:100974807|CLCN5; chloride channel, voltage-sensitive 5; K05012 chloride channel 3/4/5 (A)"	--	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	H(+)/Cl(-) exchange transporter 5 GN=CLCN5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: H(+)/Cl(-) exchange transporter 5 isoform X1 [Galeopterus variegatus] 
ENSG00000171368(TPPP)	--	2.42416245	323	1.51399	203	1.80554	244	1.148248	153	1.417342	193	0.813355	109	1.71E-05	-1.101039232	down	0.962432755	-0.093590277	normal	3.27E-05	-1.159797611	down	0.050551669	-0.780893963	normal	--	--	--	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	p25-alpha	Tubulin polymerization-promoting protein GN=TPPP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tubulin polymerization-promoting protein [Galeopterus variegatus]
ENSG00000171388(APLN)	--	0.921936	54	0.46052	28	0.590206	35	0.856969	50	0.90357	52	0.679069	40	0.976579719	-0.137787932	normal	0.76240826	0.837979635	normal	0.980020329	0.177187668	normal	0.728258727	0.257490393	normal	--	--	--	"K05225|4.66487e-26|hsa:8862|APLN, APEL, XNPEP2; apelin; K05225 apelin (A)"	--	--	--	APJ endogenous ligand	Apelin-13 (Precursor) GN=APLN OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: apelin [Canis lupus familiaris]
ENSG00000171401(KRT13)	--	0	0	0.187530073	6	0.031239838	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|ptr:100610505|KRT13; keratin 13; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 13 GN=KRT13 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 13 [Pantholops hodgsonii]"
ENSG00000171408(PDE7B)	--	7.489269234	485	6.839981583	392	7.183953286	449	5.305810763	374	5.759635105	371	5.542572594	355	0.730144314	-0.404315432	normal	0.963751371	-0.100462565	normal	0.843349434	-0.345874593	normal	0.217738062	-0.29082466	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K18436|0|ptr:747541|PDE7B; phosphodiesterase 7B; K18436 high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase	"cAMP-specific 3',5'-cyclic phosphodiesterase 7B GN=PDE7B OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 7B isoform X2 [Myotis brandtii] "
ENSG00000171421(MRPL36)	--	66.5375023	436	70.56538725	473	71.876909	484	75.0659296	515	69.77435435	456	64.98414303	433	0.944477601	0.20873466	normal	0.967794924	-0.073991958	normal	0.9556201	-0.168374933	normal	0.985148518	-0.010294534	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02919|1.13745e-43|ptr:750868|MRPL36; mitochondrial ribosomal protein L36; K02919 large subunit ribosomal protein L36 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L36	"39S ribosomal protein L36, mitochondrial (Precursor) GN=MRPL36 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L36, mitochondrial [Myotis davidii]"
ENSG00000171425(ZNF581)	--	95.66470534	1947	86.24223296	1784	92.56506913	1849	89.28900533	1677	85.90415302	1716	84.87382057	1740	0.955162868	-0.245993047	normal	0.983488896	-0.077425693	normal	0.983117162	-0.095868517	normal	0.487577431	-0.141530229	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 581 GN=ZNF581 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 581 isoform X1 [Mustela putorius furo] 
ENSG00000171428(NAT1)	--	3.764149246	106	2.976443665	79	3.052681403	86	4.339676393	120	4.302127765	121	3.346796547	93	0.96417192	0.146146143	normal	0.702278333	0.584552472	normal	0.969769052	0.102862841	normal	0.561788322	0.279628295	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Biological Process: metabolic process (GO:0008152);; Molecular Function: acetyltransferase activity (GO:0016407);; 	K00622|0|pon:100435042|NAT1; N-acetyltransferase 1 (arylamine N-acetyltransferase); K00622 arylamine N-acetyltransferase [EC:2.3.1.5] (A)	Caffeine metabolism (ko00232);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	--	--	N-acetyltransferase	Arylamine N-acetyltransferase 1 GN=NAT1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: arylamine N-acetyltransferase 1 isoform X1 [Galeopterus variegatus]
ENSG00000171431(KRT20)	--	0.0561546	2	0	0	0.0827816	2	0.111104	4	0.108499	3	0.11092	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:54474|KRT20, CD20, CK-20, CK20, K20, KRT21; keratin 20; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 20 GN=KRT20 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 20 [Loxodonta africana]"
ENSG00000171435(KSR2)	--	0.369437496	50	0.432839147	52	0.148111201	37	0.373563021	74	0.65885493	143	0.800418672	87	0.900560367	0.521520486	normal	3.30E-05	1.412238353	up	0.021773101	1.192501097	normal	0.051064393	1.107950963	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K18529|0|ptr:742520|KSR2; kinase suppressor of ras 2; K18529 kinase suppressor of Ras 2 [EC:2.7.11.1] (A)	Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SAM like domain present in kinase suppressor RAS 1	Kinase suppressor of Ras 2 GN=KSR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kinase suppressor of Ras 2 [Camelus bactrianus]
ENSG00000171443(ZNF524)	--	18.252602	279	16.48743001	271	16.755393	259	12.9914687	195	11.670459	179	13.92368	217	0.438485605	-0.544018585	normal	0.250729215	-0.615501586	normal	0.926406917	-0.261875696	normal	0.072640106	-0.473993105	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 524 GN=ZNF524 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 524 [Leptonychotes weddellii]
ENSG00000171444(MCC)	--	1.49337014	242	1.447878	229	1.391820956	225	0.506082182	83	0.5900383	95	0.574789037	96	4.08E-09	-1.556946796	down	5.26E-06	-1.277247511	down	1.59E-05	-1.224132845	down	2.23E-07	-1.365700408	down	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	PDZ domain of MCC-2 bdg protein for Usher syndrome;; EF-hand domain pair;; EF hand;; EF-hand domain	Colorectal mutant cancer protein GN=MCC OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: colorectal mutant cancer protein isoform X1 [Equus caballus]
ENSG00000171446(KRT27)	--	0	0	0	0	0.0306246	0	0.0624359	2	0	0	0.0938007	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:342574|KRT27, KRT25C; keratin 27; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 27 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 27 [Tupaia chinensis]"
ENSG00000171448(ZBTB26)	--	3.989456	258	4.243846964	279	3.589679047	237	2.915364652	201	2.887940093	195	3.143734572	210	0.82418378	-0.388379611	normal	0.477196227	-0.534730797	normal	0.951703761	-0.181557629	normal	0.187029913	-0.374325643	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10505|0|mcf:102120027|ZBTB26; zinc finger and BTB domain containing 26; K10505 zinc finger and BTB domain-containing protein 26 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 26 GN=ZBTB26 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 26 isoform X2 [Oryctolagus cuniculus] 
ENSG00000171450(CDK5R2)	--	1.15203	42	0.56412	21	0.596602	22	0.867122	32	0.580447	21	0.723774	27	0.968023403	-0.406075524	normal	0.987648728	-0.019987229	normal	0.983995618	0.270363974	normal	0.927096463	-0.109823563	normal	--	--	Cellular Component: cyclin-dependent protein kinase 5 holoenzyme complex (GO:0016533);; Molecular Function: cyclin-dependent protein kinase 5 activator activity (GO:0016534);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cyclin-dependent kinase 5 activator protein	Cyclin-dependent kinase 5 activator 2 (Precursor) GN=CDK5R2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 5 activator 2 [Ceratotherium simum simum]
ENSG00000171451(DSEL)	--	1.32364	208	1.32027	206	1.13659	175	1.51806	239	1.4135	221	1.57621	247	0.95414609	0.168433521	normal	0.963327756	0.079412566	normal	0.654005826	0.485317872	normal	0.473303313	0.242025755	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	--	--	--	--	Sulfotransferase domain	Dermatan-sulfate epimerase-like protein (Precursor) GN=DSEL OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: dermatan-sulfate epimerase-like protein [Galeopterus variegatus] 
ENSG00000171453(POLR1C)	--	21.091985	326	21.366934	412	25.01942451	366	23.957144	414	20.78501873	376	28.60930649	448	0.883076571	0.312616591	normal	0.956687333	-0.152751058	normal	0.907001	0.28230763	normal	0.624874209	0.144208339	normal	[K]	Transcription	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K03027|0|ptr:736609|POLR1C; polymerase (RNA) I polypeptide C, 30kDa; K03027 DNA-directed RNA polymerases I and III subunit RPAC1 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpb3/RpoA insert domain;; RNA polymerase Rpb3/Rpb11 dimerisation domain	DNA-directed RNA polymerases I and III subunit RPAC1 GN=POLR1C OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerases I and III subunit RPAC1 [Tupaia chinensis] 
ENSG00000171456(ASXL1)	--	17.8832318	2283	18.02681171	2321	18.19859201	2343	18.04923491	2373	25.7761561	2558	19.6176121	2727	0.988075654	0.02493252	normal	0.984629872	0.118769451	normal	0.973309652	0.21054023	normal	0.574552898	0.119846469	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: transcription, DNA-templated (GO:0006351);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K11471|0|pps:100972931|ASXL1; additional sex combs like transcriptional regulator 1; K11471 additional sex combs-like protein (A)	--	--	--	"Asx homology domain;; PHD domain of transcriptional enhancer, Asx;; HB1, ASXL, restriction endonuclease HTH domain"	Putative Polycomb group protein ASXL1 GN=ASXL1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: putative Polycomb group protein ASXL1 [Ceratotherium simum simum]
ENSG00000171462(DLK2)	--	4.461152	92	2.928352	65	3.243558806	87	2.2414183	53	2.577299	57	1.55283837	42	0.403759811	-0.808452327	normal	0.968773646	-0.205787354	normal	0.097294497	-1.032531395	normal	0.120712638	-0.704307831	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	EGF-like domain;; Human growth factor-like EGF;; EGF-like domain	Protein delta homolog 2 (Precursor) GN=DLK2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein delta homolog 2 isoform X1 [Leptonychotes weddellii]
ENSG00000171466(ZNF562)	--	5.93119921	589	5.687688097	613	5.216891899	546	4.4755023	506	4.224132074	459	5.292568514	567	0.928142347	-0.249260149	normal	0.627353089	-0.437567218	normal	0.972016673	0.046031225	normal	0.358230248	-0.211361592	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:54811|ZNF562; zinc finger protein 562; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger"	Zinc finger protein 562 GN=ZNF562 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 426-like [Galeopterus variegatus]
ENSG00000171467(ZNF318)	--	4.010787567	666	4.2877881	747	4.508201371	737	3.388774894	598	3.2778127	553	3.980762336	699	0.954797316	-0.185756415	normal	0.556112605	-0.454182264	normal	0.972679679	-0.084485571	normal	0.249698436	-0.237520209	normal	--	--	--	--	--	--	--	--	Zinc finger protein 318 GN=ZNF318 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	"PREDICTED: zinc finger protein 318, partial [Ceratotherium simum simum]"
ENSG00000171469(ZNF561)	--	5.87957303	326	5.955760265	347	5.872344924	358	7.225318417	436	5.56533629	323	6.264219663	426	0.778186376	0.387041896	normal	0.960110763	-0.124266561	normal	0.930612289	0.241665467	normal	0.528927261	0.179543844	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:93134|ZNF561; zinc finger protein 561; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 561 GN=ZNF561 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 426-like [Galeopterus variegatus]
ENSG00000171475(WIPF2)	--	17.82864014	2093	17.99129835	2130	17.7633676	1993	17.65594674	2036	18.4842758	2037	18.02017069	2145	0.985848548	-0.070614452	normal	0.984942598	-0.085771728	normal	0.984554645	0.097673042	normal	0.947441852	-0.020678716	normal	--	--	Molecular Function: actin binding (GO:0003779);; 	--	--	[Z]	Cytoskeleton	WH2 motif	WAS/WASL-interacting protein family member 2 GN=WIPF2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: WAS/WASL-interacting protein family member 2 isoform X1 [Mustela putorius furo] 
ENSG00000171488(LRRC8C)	--	4.84965	503	4.58975	470	4.75676	480	7.19562	750	7.12965	740	3.92045	408	0.212222488	0.544130748	normal	0.055718408	0.631804881	normal	0.930742766	-0.241928985	normal	0.42617991	0.362725128	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine-rich repeat containing protein 8;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies)	Volume-regulated anion channel subunit LRRC8C GN=LRRC8C OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 8C isoform X3 [Canis lupus familiaris]
ENSG00000171490(RSL1D1)	--	78.47277829	4436	82.96463839	4567	78.42129146	4372	88.59361445	4737	78.3826769	4658	77.3083271	4191	0.992348887	0.063860638	normal	0.992750512	0.007034985	normal	0.991781714	-0.069265848	normal	0.999953667	0.000992039	normal	--	--	--	"K14775|0|hsa:26156|RSL1D1, CSIG, PBK1, UTP30; ribosomal L1 domain containing 1; K14775 ribosome biogenesis protein UTP30 (A)"	--	[S]	Function unknown	Ribosomal protein L1p/L10e family	Ribosomal L1 domain-containing protein 1 GN=L12 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: ribosomal L1 domain-containing protein 1 [Equus przewalskii]
ENSG00000171492(LRRC8D)	--	22.53999385	1215	22.18649079	1245	23.59203052	1262	19.25336062	1162	18.90834202	1066	24.512543	1313	0.978173611	-0.095055576	normal	0.944737564	-0.245042812	normal	0.981655655	0.048806223	normal	0.691174648	-0.092746153	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine-rich repeat containing protein 8;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies)	Volume-regulated anion channel subunit LRRC8D GN=LRRC8D OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 8D isoform X1 [Tupaia chinensis] 
ENSG00000171495(MROH2B)	--	0	0	0	0	0	0	0.013270749	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	HEAT repeat	Maestro heat-like repeat-containing protein family member 2B GN=MROH2B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: maestro heat-like repeat-containing protein family member 2B isoform X5 [Tupaia chinensis]
ENSG00000171496(OR1L8)	--	0	0	0	0	0	0	0.098608	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:138881|OR1L8, OR9-24; olfactory receptor, family 1, subfamily L, member 8; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 1L8 GN=OR1L8 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 1L8-like [Tupaia chinensis] 
ENSG00000171497(PPID)	--	22.93749086	686	21.4767	653	24.24013	724	27.38994	836	20.61080713	614	20.97969	629	0.930278189	0.253946234	normal	0.968053438	-0.110008102	normal	0.948235355	-0.210748419	normal	0.983948554	-0.010884858	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein folding (GO:0006457);; 	"K05864|0|hsa:5481|PPID, CYP-40, CYPD; peptidylprolyl isomerase D (EC:5.2.1.8); K05864 peptidyl-prolyl isomerase D [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Peptidyl-prolyl cis-trans isomerase D GN=PPID OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase D [Orycteropus afer afer]
ENSG00000171502(COL24A1)	--	0.0134619	2	0	0	0	0	0.00668693	1	0.0262511	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; 	"K06236|0|hsa:255631|COL24A1; collagen, type XXIV, alpha 1; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; Laminin G domain	Collagen alpha-1(XXIV) chain (Precursor) GN=COL24A1 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(XXIV) chain [Ceratotherium simum simum]
ENSG00000171503(ETFDH)	--	4.812481476	204	3.704222417	178	4.240173027	186	5.031096545	220	6.024636	247	3.50267961	168	0.964634804	0.077539699	normal	0.738420184	0.44796347	normal	0.958060497	-0.153816303	normal	0.730151798	0.139036491	normal	[C]	Energy production and conversion	--	K00311|0|ptr:461573|ETFDH; electron-transferring-flavoprotein dehydrogenase; K00311 electron-transferring-flavoprotein dehydrogenase [EC:1.5.5.1] (A)	--	[C]	Energy production and conversion	Electron transfer flavoprotein-ubiquinone oxidoreductase;; FAD dependent oxidoreductase;; FAD binding domain;; Thi4 family;; NAD(P)-binding Rossmann-like domain;; Pyridine nucleotide-disulphide oxidoreductase;; FAD-NAD(P)-binding;; FAD binding domain	"Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (Precursor) GN=ETFDH OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial [Felis catus] "
ENSG00000171517(LPAR3)	--	0.306120223	12	0.18345799	11	0.347647395	16	0.238924346	9	0.350910289	11	0.097237518	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04294|0|hsa:23566|LPAR3, EDG7, Edg-7, GPCR, HOFNH30, LP-A3, LPA3, RP4-678I3; lysophosphatidic acid receptor 3; K04294 lysophosphatidic acid receptor 3 (A)"	Rap1 signaling pathway (ko04015);; Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Lysophosphatidic acid receptor 3 GN=LPAR3 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: lysophosphatidic acid receptor 3 [Ceratotherium simum simum]
ENSG00000171522(PTGER4)	--	1.099250303	70	1.38095	81	1.936943	84	0.915298	46	0.858549	51	0.495675683	32	0.84691316	-0.619647004	normal	0.733850139	-0.672875612	normal	0.00453083	-1.359472599	down	0.045751031	-0.887165716	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04261|0|hsa:5734|PTGER4, EP4, EP4R; prostaglandin E receptor 4 (subtype EP4); K04261 prostaglandin E receptor 4 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Inflammatory mediator regulation of TRP channels (ko04750);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srx	Prostaglandin E2 receptor EP4 subtype GN=PTGER4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: prostaglandin E2 receptor EP4 subtype [Tupaia chinensis] 
ENSG00000171530(TBCA)	--	147.673228	1522	140.3137611	1478	145.1468796	1510	156.0853297	1677	149.0023563	1507	141.5018921	1484	0.98079075	0.108977241	normal	0.983591881	0.006599902	normal	0.983718404	-0.033315242	normal	0.920716157	0.028108045	normal	--	--	Biological Process: tubulin complex assembly (GO:0007021);; Biological Process: post-chaperonin tubulin folding pathway (GO:0007023);; Molecular Function: beta-tubulin binding (GO:0048487);; 	K17292|4.55153e-40|ptr:737862|TBCA; tubulin folding cofactor A; K17292 tubulin-specific chaperone A (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin binding cofactor A	Tubulin-specific chaperone A GN=TBCA OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin-specific chaperone A [Ochotona princeps]
ENSG00000171532(NEUROD2)	--	0	0	0.0324269	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09078|0|ngi:103743817|Neurod2; neuronal differentiation 2; K09078 neurogenic differentiation factor 2 (A)	--	[K]	Transcription	Neuronal helix-loop-helix transcription factor;; Helix-loop-helix DNA-binding domain	Neurogenic differentiation factor 2 GN=NEUROD2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: neurogenic differentiation factor 2 [Oryctolagus cuniculus]
ENSG00000171533(MAP6)	--	2.255145108	130	1.981977	128	1.237350223	78	1.060828769	68	1.8010316	119	1.654777	96	0.037261804	-0.949932627	normal	0.963168083	-0.125075753	normal	0.951230137	0.286257897	normal	0.643252981	-0.268552954	normal	--	--	--	"K10432|0|hsa:4135|MAP6, MTAP6, N-STOP, STOP; microtubule-associated protein 6; K10432 microtubule-associated protein 6 (A)"	--	--	--	STOP protein	Microtubule-associated protein 6 GN=MAP6 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: microtubule-associated protein 6 [Odobenus rosmarus divergens]
ENSG00000171540(OTP)	--	0.0352024	2	0.0869768	5	0.0168725	0	0.0349098	2	0.0675845	3	0.034457	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Homeobox protein orthopedia GN=OTP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: homeobox protein orthopedia [Loxodonta africana]
ENSG00000171551(ECEL1)	--	0.103302737	5	0.11582669	5	0.058292401	2	0	0	0	0	0.047180973	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K09610|0|ggo:101133364|ECEL1; endothelin-converting enzyme-like 1; K09610 endothelin-converting enzyme-like 1 [EC:3.4.24.-] (A)	--	[E]	Amino acid transport and metabolism	Peptidase family M13;; Peptidase family M13	Endothelin-converting enzyme-like 1 GN=ECEL1 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: endothelin-converting enzyme-like 1 isoform 2 [Ceratotherium simum simum]
ENSG00000171552(BCL2L1)	--	114.3940489	5341	105.6915356	4869	131.90553	6047	139.5713085	6409	126.81054	5857	149.7187962	6875	0.982313779	0.232096108	normal	0.978563045	0.245040362	normal	0.989678552	0.176807197	normal	0.255166606	0.214911917	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K04570|4.90704e-172|ptr:458156|BCL2L1; BCL2-like 1; K04570 BCL2-like 1 (apoptosis regulator Bcl-X) (A)	Ras signaling pathway (ko04014);; NF-kappa B signaling pathway (ko04064);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Jak-STAT signaling pathway (ko04630);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Toxoplasmosis (ko05145);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Pancreatic cancer (ko05212);; Chronic myeloid leukemia (ko05220);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	"Apoptosis regulator proteins, Bcl-2 family;; Bcl-2 homology region 4"	Bcl-2-like protein 1 GN=BCL2L1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bcl-2-like protein 1 isoform X1 [Panthera tigris altaica] 
ENSG00000171557(FGG)	--	0.268966969	8	0.163957322	5	0.422662384	10	4.374512665	116	7.692750969	235	7.935208243	246	0	3.595363024	up	0	5.163738254	up	0	4.418532169	up	3.31E-09	4.679869557	up	--	--	"Molecular Function: receptor binding (GO:0005102);; Cellular Component: fibrinogen complex (GO:0005577);; Biological Process: signal transduction (GO:0007165);; Biological Process: platelet activation (GO:0030168);; Molecular Function: protein binding, bridging (GO:0030674);; Biological Process: protein polymerization (GO:0051258);; "	K03905|0|mcc:698363|FGG; fibrinogen gamma chain; K03905 fibrinogen gamma chain (A)	Complement and coagulation cascades (ko04610);; Platelet activation (ko04611);; Staphylococcus aureus infection (ko05150)	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain;; Fibrinogen alpha/beta chain family"	Fibrinogen gamma chain (Precursor) GN=FGG OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: fibrinogen gamma chain isoform X1 [Galeopterus variegatus]
ENSG00000171560(FGA)	--	2.211044957	110	1.893038367	94	1.615656795	79	6.869008639	357	11.96462177	610	25.03105296	1288	2.87E-12	1.654050442	up	0	2.657392775	up	0	3.993264005	up	0.027260768	2.976307446	normal	--	--	"Molecular Function: receptor binding (GO:0005102);; Cellular Component: fibrinogen complex (GO:0005577);; Biological Process: signal transduction (GO:0007165);; Biological Process: platelet activation (GO:0030168);; Molecular Function: protein binding, bridging (GO:0030674);; Biological Process: protein polymerization (GO:0051258);; "	"K03903|0|hsa:2243|FGA, Fib2; fibrinogen alpha chain; K03903 fibrinogen alpha chain (A)"	Complement and coagulation cascades (ko04610);; Platelet activation (ko04611)	--	--	"Fibrinogen beta and gamma chains, C-terminal globular domain;; Fibrinogen alpha/beta chain family;; Fibrinogen alpha C domain"	Fibrinogen alpha chain (Precursor) GN=FGA OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: fibrinogen alpha chain [Oryctolagus cuniculus]
ENSG00000171564(FGB)	--	0.074944559	3	0.134208344	3	0.049520294	1	4.193858	165	6.964475955	278	11.17009	424	0	5.172661748	up	0	5.935134428	up	0	7.398275774	up	1.52E-09	6.932522942	up	--	--	"Molecular Function: receptor binding (GO:0005102);; Cellular Component: fibrinogen complex (GO:0005577);; Biological Process: signal transduction (GO:0007165);; Biological Process: platelet activation (GO:0030168);; Molecular Function: protein binding, bridging (GO:0030674);; Biological Process: protein polymerization (GO:0051258);; "	K03904|0|ggo:101133258|FGB; fibrinogen beta chain; K03904 fibrinogen beta chain (A)	Complement and coagulation cascades (ko04610);; Platelet activation (ko04611)	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain;; Fibrinogen alpha/beta chain family"	Fibrinogen beta chain (Precursor) GN=FGB OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: fibrinogen beta chain [Galeopterus variegatus]
ENSG00000171566(PLRG1)	--	21.45240216	1055	20.18169636	1025	19.48242998	975	20.5256208	932	24.10904322	977	21.95626013	1030	0.95527635	-0.20934875	normal	0.975888562	-0.090483242	normal	0.977725887	0.07077196	normal	0.760692128	-0.076836041	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K12862|0|ptr:461557|PLRG1; pleiotropic regulator 1; K12862 pleiotropic regulator 1 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"WD domain, G-beta repeat;; Nup133 N terminal like;; Nucleoporin Nup120/160"	Pleiotropic regulator 1 GN=PLRG1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: pleiotropic regulator 1 [Tupaia chinensis]
ENSG00000171574(ZNF584)	--	15.58319788	411	15.20115301	403	11.230579	390	15.80206391	402	15.34786147	415	15.5195793	343	0.968057085	-0.062538754	normal	0.968908139	0.020827921	normal	0.94812132	-0.192759377	normal	0.828193378	-0.075378362	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:201514|ZNF584; zinc finger protein 584; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 584 GN=ZNF584 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 584-like [Galeopterus variegatus]
ENSG00000171596(NMUR1)	--	0	0	0.0341705	2	0.0167837	0	0	0	0.0169266	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05052|0|hsa:10316|NMUR1, (FM-3), FM-3, FM3, GPC-R, GPR66, NMU1R; neuromedin U receptor 1; K05052 neuromedin U receptor 1 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srw	Neuromedin-U receptor 1 GN=NMUR1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuromedin-U receptor 1 [Ceratotherium simum simum]
ENSG00000171603(CLSTN1)	--	39.18422419	3798	39.8836296	3906	37.40353815	3715	50.6037402	4942	52.56851488	5100	49.55804	4824	0.915569544	0.348898811	normal	0.904203217	0.363255336	normal	0.888664342	0.368444276	normal	0.024668515	0.359274297	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	--	--	[W]	Extracellular structures	Cadherin domain;; Concanavalin A-like lectin/glucanases superfamily	CTF1-alpha (Precursor) GN=CLSTN1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: calsyntenin-1 isoform X1 [Tupaia chinensis]
ENSG00000171606(ZNF274)	--	8.57221571	504	7.91519961	425	8.584567371	525	10.10356766	592	8.68740959	446	10.81290271	574	0.948533709	0.200775997	normal	0.968639987	0.047987621	normal	0.96583142	0.120110889	normal	0.643296958	0.127668264	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K12458|0|pps:100975549|ZNF274; zinc finger protein 274; K12458 zinc finger protein 274 (A)	Neurotrophin signaling pathway (ko04722)	[R]	General function prediction only	"KRAB box;; SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding"	Neurotrophin receptor-interacting factor homolog GN=ZNF274 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: neurotrophin receptor-interacting factor homolog isoform X1 [Galeopterus variegatus]
ENSG00000171608(PIK3CD)	--	4.901811015	502	3.754683643	388	4.657693821	470	5.183700073	530	4.673448768	477	3.39370771	341	0.971050834	0.047331743	normal	0.911199899	0.275536023	normal	0.545916465	-0.469399462	normal	0.950033783	-0.035059035	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; 	"K00922|0|mcf:102143464|PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; K00922 phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153] (A)"	Inositol phosphate metabolism (ko00562);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; HIF-1 signaling pathway (ko04066);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Aldosterone-regulated sodium reabsorption (ko04960);; Carbohydrate digestion and absorption (ko04973);; Bacterial invasion of epithelial cells (ko05100);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Pancreatic cancer (ko05212);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	"Phosphatidylinositol 3- and 4-kinase;; Phosphoinositide 3-kinase family, accessory domain (PIK domain);; Phosphoinositide 3-kinase C2;; PI3-kinase family, p85-binding domain;; PI3-kinase family, ras-binding domain"	"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform GN=PIK3CD OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1 [Felis catus] "
ENSG00000171612(SLC25A33)	--	3.031328052	202	3.60651621	241	2.575983897	171	2.232035512	150	2.357377048	157	2.9206168	196	0.760597722	-0.456181845	normal	0.245820591	-0.634720705	normal	0.952453099	0.187019926	normal	0.360462383	-0.308555727	normal	--	--	--	"K15116|0|nle:100607867|SLC25A33; solute carrier family 25 (pyrimidine nucleotide carrier), member 33; K15116 solute carrier family 25, member 33/36 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Solute carrier family 25 member 33 GN=SLC25A33 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 33 isoform X2 [Canis lupus familiaris]
ENSG00000171617(ENC1)	--	20.91151318	2035	20.32362691	1997	23.87199572	2199	15.25432583	1456	14.11014563	1300	13.38402278	1246	0.283240906	-0.513390048	normal	0.028123307	-0.640143513	normal	0.000125719	-0.827068969	normal	2.53E-06	-0.66026571	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10462|0|hsa:8507|ENC1, CCL28, ENC-1, KLHL35, KLHL37, NRPB, PIG10, TP53I10; ectodermal-neural cortex 1 (with BTB domain); K10462 kelch-like protein 25/37 (ectoderm-neural cortex protein) (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; BTB/POZ domain;; BTB And C-terminal Kelch;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Ectoderm-neural cortex protein 1 GN=ENC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ectoderm-neural cortex protein 1 [Canis lupus familiaris]
ENSG00000171621(SPSB1)	--	12.18179519	587	9.258973839	543	9.464857656	521	10.93014147	634	12.22710152	642	16.1284445	833	0.970957246	0.080088347	normal	0.942615602	0.219631462	normal	0.020832106	0.667196396	normal	0.137459387	0.332708045	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10343|0|cfa:479598|SPSB1; splA/ryanodine receptor domain and SOCS box containing 1; K10343 SPRY domain-containing SOCS box protein 1/4 (A)	--	[R]	General function prediction only	SPRY domain;; SOCS box	SPRY domain-containing SOCS box protein 1 GN=SPSB1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SPRY domain-containing SOCS box protein 1 isoform X1 [Canis lupus familiaris]
ENSG00000171631(P2RY6)	--	4.250773953	117	4.2867065	132	3.886923633	59	9.131991772	265	11.00884832	292	6.97217249	171	3.27E-05	1.138458313	up	3.40E-05	1.115198353	up	9.30E-07	1.50324759	up	0.006072939	1.217619398	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04272|0|hsa:5031|P2RY6, P2Y6; pyrimidinergic receptor P2Y, G-protein coupled, 6; K04272 pyrimidinergic receptor P2Y, G protein-coupled, 6 (A)"	Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family)	P2Y purinoceptor 6 GN=P2RY6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: P2Y purinoceptor 6 isoform X1 [Physeter catodon] 
ENSG00000171634(BPTF)	--	15.57006942	3242	19.57127846	3697	19.74798094	3489	17.30223596	3116	19.35339971	3792	20.18120661	4100	0.989070101	-0.087978586	normal	0.991453076	0.015171235	normal	0.977191266	0.224429043	normal	0.837459499	0.057731991	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	K11728|0|ggo:101132650|BPTF; nucleosome-remodeling factor subunit BPTF; K11728 nucleosome-remodeling factor subunit BPTF (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	"Bromodomain;; DDT domain;; PHD-finger;; WSTF, HB1, Itc1p, MBD9 motif 1"	Nucleosome-remodeling factor subunit BPTF GN=BPTF OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nucleosome-remodeling factor subunit BPTF isoform X6 [Camelus bactrianus]
ENSG00000171649(ZIK1)	--	0	0	0	0	0	0	0	0	0	0	0.029789953	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:284307|ZIK1, ZNF762; zinc finger protein interacting with K protein 1; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box"	Zinc finger protein interacting with ribonucleoprotein K GN=ZIK1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein interacting with ribonucleoprotein K-like [Galeopterus variegatus]
ENSG00000171657(GPR82)	--	0	0	0.123102	6	0	0	0.0403133	2	0.0787576	3	0.0605676	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08420|0|hsa:27197|GPR82; G protein-coupled receptor 82; K08420 G protein-coupled receptor 82 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 82 GN=GPR82 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 82 [Galeopterus variegatus]
ENSG00000171659(GPR34)	--	0.182483	4	0	0	0.0669671	0	0.045234345	1	0.30572	5	0.22569096	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08383|0|ptr:473572|GPR34; G protein-coupled receptor 34; K08383 G protein-coupled receptor 34 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 34 GN=GPR34 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: probable G-protein coupled receptor 34 [Equus caballus]
ENSG00000171680(PLEKHG5)	--	2.931295096	243	1.137728385	114	3.120450525	191	3.376297762	266	3.71617503	311	1.600279596	189	0.962984789	0.09903905	normal	1.63E-08	1.414632116	up	0.966875809	-0.023292448	normal	0.389305572	0.461495757	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Pleckstrin homology domain-containing family G member 5 GN=PLEKHG5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family G member 5 isoform X1 [Galeopterus variegatus]
ENSG00000171681(ATF7IP)	--	6.428228246	854	6.079365419	651	8.046558491	650	8.443655503	1078	7.61717812	1128	7.25579851	1002	0.896160566	0.304728081	normal	0.001588953	0.770235603	normal	0.052792728	0.614918416	normal	0.000376778	0.552429452	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	--	Activating transcription factor 7-interacting protein 1 GN=ATF7IP OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: activating transcription factor 7-interacting protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000171695(LKAAEAR1)	--	0.575277318	6	0.501403	5	0.68888	7	0.686447	7	0.274542	2	0.371981383	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Family of unknown function with LKAAEAR motif	Protein LKAAEAR1 GN=LKAAEAR1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C20orf201 homolog [Odobenus rosmarus divergens]
ENSG00000171700(RGS19)	--	16.98549	435	12.4999	328	15.817245	430	11.17882	296	11.52041	296	9.3666	244	0.187349357	-0.583734058	normal	0.952405224	-0.168705944	normal	0.002716782	-0.821857784	normal	0.014036188	-0.53445283	normal	--	--	--	K16449|3.05728e-146|ptr:458459|RGS19; regulator of G-protein signaling 19; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 19 GN=RGS19 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 19 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000171703(TCEA2)	--	18.545791	494	13.297739	416	16.55630787	515	18.5217438	508	22.217365	581	16.31439589	435	0.971712842	0.00945619	normal	0.563454969	0.459109882	normal	0.92642749	-0.251045346	normal	0.811302178	0.07564512	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: zinc ion binding (GO:0008270);; "	"K03145|0|ptr:740775|TCEA2; transcription elongation factor A (SII), 2; K03145 transcription elongation factor S-II (A)"	--	[K]	Transcription	"Transcription factor S-II (TFIIS), central domain;; Transcription factor S-II (TFIIS);; TFIIS helical bundle-like domain"	Transcription elongation factor A protein 2 GN=TCEA2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription elongation factor A protein 2 [Orcinus orca]
ENSG00000171714(ANO5)	--	6.061041713	666	5.514725472	614	5.479373454	599	4.542877508	506	4.735389461	525	4.792384686	530	0.645452353	-0.426085272	normal	0.930026167	-0.246689921	normal	0.953903309	-0.184359928	normal	0.162301981	-0.288631196	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[S]	Function unknown	Calcium-activated chloride channel	Anoctamin-5 GN=ANO5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: anoctamin-5 [Pteropus alecto]
ENSG00000171720(HDAC3)	--	24.13407953	842	21.5474	748	20.35015179	712	27.18957307	948	26.77624306	922	24.60655108	848	0.969293951	0.139993727	normal	0.91602631	0.279791627	normal	0.936738067	0.243421265	normal	0.270596973	0.217981092	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	K11404|0|umr:103663723|HDAC3; histone deacetylase 3; K11404 histone deacetylase 3 [EC:3.5.1.98] (A)	Thyroid hormone signaling pathway (ko04919);; Alcoholism (ko05034);; Viral carcinogenesis (ko05203)	[B]	Chromatin structure and dynamics	Histone deacetylase domain	Histone deacetylase 3 GN=HDAC3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 3 isoform X1 [Mustela putorius furo] 
ENSG00000171722(SPATA46)	--	0	0	0	0	0.0328903	0	0.100779	3	0.0327869	0	0.0998028	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf111 GN=C1orf111 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C1orf111 homolog [Loxodonta africana]
ENSG00000171723(GPHN)	--	7.467066001	466	7.80255489	494	8.499700045	487	8.162890078	526	8.582274238	506	6.855383768	382	0.961076003	0.143455221	normal	0.970973419	0.01315998	normal	0.823646637	-0.357384309	normal	0.874673854	-0.055332454	normal	[H]	Coenzyme transport and metabolism	Biological Process: molybdopterin cofactor biosynthetic process (GO:0032324);; 	K15376|0|ptr:452976|GPHN; gephyrin; K15376 gephyrin [EC:2.10.1.1 2.7.7.75] (A)	GABAergic synapse (ko04727)	[H]	Coenzyme transport and metabolism	Probable molybdopterin binding domain;; MoeA N-terminal region (domain I and II);; MoeA C-terminal region (domain IV)	Molybdopterin molybdenumtransferase GN=GPHN OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: gephyrin isoform X1 [Orycteropus afer afer]
ENSG00000171724(VAT1L)	--	0	0	0	0	0	0	0.0135487	1	0.0396336	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[CR]	Energy production and conversion;; General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[CR]	Energy production and conversion;; General function prediction only	Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase;; Zinc-binding dehydrogenase	Synaptic vesicle membrane protein VAT-1 homolog-like GN=VAT1L OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: synaptic vesicle membrane protein VAT-1 homolog-like [Orycteropus afer afer]
ENSG00000171729(TMEM51)	--	14.94684152	503	14.20271181	480	15.63036757	550	18.21171931	623	17.503131	625	16.98278282	536	0.910784115	0.277079866	normal	0.818973638	0.358403137	normal	0.971783616	-0.045363704	normal	0.398456834	0.197378687	normal	--	--	--	--	--	--	--	Transmembrane protein 51	Transmembrane protein 51 GN=TMEM51 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 51 [Camelus ferus] 
ENSG00000171735(CAMTA1)	--	36.53790098	411	31.2607177	358	32.79068088	403	39.18298438	423	44.48024324	462	40.40331415	433	0.969990229	0.010647771	normal	0.845033616	0.345219962	normal	0.96594128	0.094951934	normal	0.602759672	0.148414519	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	--	--	[S]	Function unknown	CG-1 domain;; Ankyrin repeats (3 copies);; IPT/TIG domain;; Ankyrin repeats (many copies);; Ankyrin repeat;; IQ calmodulin-binding motif;; Ankyrin repeat	Calmodulin-binding transcription activator 1 GN=CAMTA1 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: calmodulin-binding transcription activator 1 [Equus caballus]
ENSG00000171747(LGALS4)	--	1.5827861	31	0.770701296	14	0.577320771	16	0.59809004	16	0.624008775	11	0.29597684	8	0.898963108	-0.920453079	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	"K10091|0|hsa:3960|LGALS4, GAL4, L36LBP; lectin, galactoside-binding, soluble, 4; K10091 galectin-4 (A)"	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-4 GN=LGALS4 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: galectin-4 [Physeter catodon]
ENSG00000171757(LRRC34)	--	0	0	0	0	0	0	0	0	0	0	0.290505073	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Leucine Rich repeat;; Leucine Rich Repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 34 GN=LRRC34 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 34 isoform X1 [Galeopterus variegatus]
ENSG00000171763(SPATA5L1)	--	4.706218259	192	4.488509001	184	4.248561	177	4.349186757	181	4.6478348	193	4.08293085	169	0.962109998	-0.115000834	normal	0.965068483	0.047090613	normal	0.965353557	-0.074367228	normal	0.930164126	-0.047762623	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA ATPase domain;; AAA domain (dynein-related subfamily);; Holliday junction DNA helicase ruvB N-terminus;; AAA domain;; AAA domain;; AAA domain;; AAA domain;; NTPase;; AAA domain (Cdc48 subfamily);; AAA domain;; TIP49 C-terminus;; Zeta toxin;; ATPase family associated with various cellular activities (AAA);; Viral (Superfamily 1) RNA helicase;; NACHT domain;; RNA helicase;; Vps4 C terminal oligomerisation domain;; Rad17 cell cycle checkpoint protein;; Protein of unknown function (DUF815)	Spermatogenesis-associated protein 5-like protein 1 GN=SPATA5L1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: spermatogenesis-associated protein 5-like protein 1 [Ceratotherium simum simum]
ENSG00000171766(GATM)	--	8.870931002	341	7.371961	286	8.106522688	311	5.759474789	237	6.5230858	267	6.564754472	268	0.341448009	-0.552711546	normal	0.959892708	-0.119945375	normal	0.939442758	-0.221809983	normal	0.262997853	-0.301752955	normal	--	--	--	"K00613|0|hsa:2628|GATM, AGAT, AT, CCDS3; glycine amidinotransferase (L-arginine:glycine amidinotransferase) (EC:2.1.4.1); K00613 glycine amidinotransferase [EC:2.1.4.1] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Arginine and proline metabolism (ko00330)"	--	--	Amidinotransferase	"Glycine amidinotransferase, mitochondrial (Precursor) GN=GATM OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"glycine amidinotransferase, mitochondrial [Canis lupus familiaris]"
ENSG00000171772(SYCE1)	--	0.353379	6	0.163844	3	0.374214	6	0.399273	7	0.283528	4	0.860446	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: synaptonemal complex (GO:0000795);; Biological Process: meiotic prophase I (GO:0007128);; Biological Process: synaptonemal complex assembly (GO:0007130);; Biological Process: synaptonemal complex organization (GO:0070193);; 	--	--	--	--	Synaptonemal complex central element protein 1	Synaptonemal complex central element protein 1 GN=SYCE1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: synaptonemal complex central element protein 1-like [Leptonychotes weddellii]
ENSG00000171773(NXNL1)	--	3.173842914	81	2.092231683	56	2.408730802	66	1.628883495	41	1.771051971	44	1.769999152	46	0.182289345	-0.9863198	normal	0.959402498	-0.358403	normal	0.915459713	-0.51491605	normal	0.191441632	-0.652730534	normal	--	--	--	--	--	[R]	General function prediction only	Thioredoxin-like;; Redoxin	Nucleoredoxin-like protein 1 GN=NXNL1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: nucleoredoxin-like protein 1 [Eptesicus fuscus]
ENSG00000171777(RASGRP4)	--	0.041611546	2	0.040996125	2	0.200728463	9	0.04159456	2	0.040555761	1	0.061593023	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	K12363|0|hsa:115727|RASGRP4; RAS guanyl releasing protein 4; K12363 RAS guanyl-releasing protein 4 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	RasGEF domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	RAS guanyl-releasing protein 4 GN=RASGRP4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: RAS guanyl-releasing protein 4 isoform X3 [Canis lupus familiaris]
ENSG00000171786(NHLH1)	--	0.228663	9	0.226435	9	0.246575	9	0.0253996	1	0.123612	4	0.125032	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09075|2.95354e-34|cge:100761552|Nhlh1; nescient helix loop helix 1; K09075 nescient helix-loop-helix protein (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Helix-loop-helix protein 1 GN=NHLH1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: helix-loop-helix protein 1 [Trichechus manatus latirostris]
ENSG00000171790(SLFNL1)	--	0.973244	73	1.31429	113	1.185459	98	1.34780051	113	1.59384	133	1.55999	132	0.727878322	0.589480904	normal	0.953146854	0.211070919	normal	0.880442994	0.415844457	normal	0.347590057	0.391818715	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	Divergent AAA domain	Schlafen-like protein 1 GN=SLFNL1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: schlafen-like protein 1 [Pteropus alecto]
ENSG00000171791(BCL2)	--	0.93028007	92	1.459542683	148	1.124103712	114	0.780400771	75	0.410764998	39	0.879830212	90	0.946308009	-0.319651168	normal	3.80E-09	-1.904750871	down	0.928365569	-0.344177604	normal	0.083189181	-0.81619978	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K02161|1.38084e-132|ptr:738409|BCL2; B-cell CLL/lymphoma 2; K02161 apoptosis regulator BCL-2 (A)	NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Sphingolipid signaling pathway (ko04071);; Protein processing in endoplasmic reticulum (ko04141);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; Focal adhesion (ko04510);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Colorectal cancer (ko05210);; Prostate cancer (ko05215);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	"Apoptosis regulator proteins, Bcl-2 family;; Bcl-2 homology region 4"	Apoptosis regulator Bcl-2 GN=BCL2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: apoptosis regulator Bcl-2 isoform X1 [Tupaia chinensis] 
ENSG00000171792(RHNO1)	--	28.649547	860	30.636967	838	27.378727	819	29.1083	852	25.29888244	761	32.5650137	980	0.976962086	-0.044236092	normal	0.963796245	-0.160176867	normal	0.93606881	0.250203976	normal	0.9508736	0.022037133	normal	--	--	Biological Process: DNA damage checkpoint (GO:0000077);; Cellular Component: nucleus (GO:0005634);; Biological Process: cellular response to ionizing radiation (GO:0071479);; 	--	--	--	--	"RAD9, RAD1, HUS1-interacting nuclear orphan protein"	"RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 GN=RHNO1 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: RAD9, HUS1, RAD1-interacting nuclear orphan protein 1 [Galeopterus variegatus] "
ENSG00000171793(CTPS1)	--	37.49469	2123	30.3198	1804	37.92055	2146	39.10897	2296	42.64276	2437	32.8952	1913	0.986020212	0.082128847	normal	0.741928578	0.412182062	normal	0.976560682	-0.173974714	normal	0.629591818	0.108633152	normal	[F]	Nucleotide transport and metabolism	Molecular Function: CTP synthase activity (GO:0003883);; Biological Process: pyrimidine nucleotide biosynthetic process (GO:0006221);; Biological Process: glutamine metabolic process (GO:0006541);; Molecular Function: hydrolase activity (GO:0016787);; 	K01937|0|pps:100975537|CTPS1; CTP synthase 1; K01937 CTP synthase [EC:6.3.4.2] (A)	Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	CTP synthase N-terminus;; Glutamine amidotransferase class-I;; Peptidase C26	CTP synthase 1 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: CTP synthase 1 [Lipotes vexillifer]
ENSG00000171794(UTF1)	--	0.143747	2	0	0	0.0666636	0	0	0	0	0	0.0689042	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Myb/SANT-like DNA-binding domain	Undifferentiated embryonic cell transcription factor 1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: undifferentiated embryonic cell transcription factor 1 [Eptesicus fuscus]
ENSG00000171798(KNDC1)	--	1.571445366	229	1.143459409	181	1.306779	184	0.343374967	56	0.481298943	59	0.374210018	49	8.19E-14	-2.032764109	down	5.80E-08	-1.613763602	down	1.53E-10	-1.884941975	down	9.40E-11	-1.878422721	down	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	--	--	RasGEF domain;; RasGEF N-terminal motif	Protein very KIND GN=hucep-9 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protein very KIND [Eptesicus fuscus]
ENSG00000171804(WDR87)	--	0.00407215	1	0	0	0	0	0	0	0.00398445	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 87 GN=WDR87 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: WD repeat-containing protein 87 isoform X1 [Galeopterus variegatus]
ENSG00000171806(METTL18)	--	3.9664031	93	4.324586683	109	3.94815161	100	4.7188167	108	3.54901	91	2.924953	69	0.962686374	0.182102895	normal	0.946045169	-0.277594711	normal	0.830150091	-0.533848541	normal	0.724807845	-0.194871873	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Putative methyltransferase;; Ribosomal protein L11 methyltransferase (PrmA);; Methyltransferase domain;; Methyltransferase small domain	Histidine protein methyltransferase 1 homolog GN=METTL18 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: histidine protein methyltransferase 1 homolog [Galeopterus variegatus]
ENSG00000171811(CFAP46)	--	0.4030001	11	0.4391212	14	0.551447517	14	0.739185388	22	1.6292565	41	0.7543105	31	0.959857696	0.88083056	normal	0.196569841	1.434467568	normal	0.837699707	1.059879165	normal	0.044341989	1.249267675	normal	--	--	--	--	--	--	--	--	Protein CFAP46 {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 40 [Equus przewalskii]
ENSG00000171812(COL8A2)	--	0.148856678	14	0.022652174	2	0.053211448	4	0.0492799	4	0.065390329	5	0.033127746	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Collagen triple helix repeat (20 copies);; C1q domain	Collagen alpha-2(VIII) chain (Precursor) GN=COL8A2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	hypothetical protein CB1_000884024 [Camelus ferus]
ENSG00000171813(PWWP2B)	--	16.50655	739	13.70328	634	14.95795	699	12.30052	572	12.75375	578	13.35695	627	0.719722559	-0.399444536	normal	0.96090589	-0.154453876	normal	0.960676672	-0.164741924	normal	0.24334465	-0.242434966	normal	--	--	--	--	--	--	--	PWWP domain	PWWP domain-containing protein 2B GN=PWWP2B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: PWWP domain-containing protein 2B [Tupaia chinensis]
ENSG00000171815(PCDHB1)	--	0	0	0.0149759	2	0	0	0	0	0	0	0.0148965	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:29930|PCDHB1, PCDH-BETA1; protocadherin beta 1; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-1 (Precursor) GN=PCDHB1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protocadherin beta-1 [Galeopterus variegatus]
ENSG00000171817(ZNF540)	--	0.101006622	5	0.050065	2	0.122536295	5	0.073934013	3	0.194244	7	0.402578	10	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:163255|ZNF540, Nbla10512; zinc finger protein 540; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; NTF2 fold immunity protein;; Transposase zinc-ribbon domain"	Zinc finger protein 540 GN=ZNF540 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 540 [Oryctolagus cuniculus] 
ENSG00000171819(ANGPTL7)	--	0	0	0	0	0	0	0.043815	2	0.0215405	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Angiopoietin-related protein 7 (Precursor) GN=ANGPTL7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: angiopoietin-related protein 7 [Galeopterus variegatus]
ENSG00000171823(FBXL14)	--	6.95269	246	7.8386	285	6.70452	245	8.19148	293	7.87715	278	8.95267	319	0.940366408	0.220149017	normal	0.965150247	-0.056997355	normal	0.829894309	0.370473657	normal	0.5827018	0.176611446	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10280|0|mcf:102127730|FBXL14; F-box and leucine-rich repeat protein 14; K10280 F-box and leucine-rich repeat protein 14 (A)	--	[R]	General function prediction only	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; F-box-like;; Leucine rich repeat;; F-box domain;; Leucine Rich Repeat	F-box/LRR-repeat protein 14 GN=FBXL14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 14 isoform X1 [Bos taurus]
ENSG00000171824(EXOSC10)	--	16.844748	1024	17.868585	1072	16.00221089	965	17.237654	1045	18.160029	1104	16.381796	1002	0.979939508	-0.001542745	normal	0.979917315	0.020979545	normal	0.978631794	0.045919595	normal	0.951471013	0.020379748	normal	--	--	Cellular Component: nuclear exosome (RNase complex) (GO:0000176);; Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Biological Process: RNA processing (GO:0006396);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	"K12591|0|hsa:5394|EXOSC10, PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4; exosome component 10; K12591 exosome complex exonuclease RRP6 [EC:3.1.13.-] (A)"	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	3'-5' exonuclease;; PMC2NT (NUC016) domain;; HRDC domain	Exosome component 10 GN=EXOSC10 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome component 10 isoform X1 [Galeopterus variegatus]
ENSG00000171827(ZNF570)	--	2.200963805	161	1.871855947	129	2.634048	134	1.2590137	125	1.36732667	118	1.688954	135	0.873962661	-0.391709546	normal	0.961145773	-0.148193544	normal	0.968452973	0.002407891	normal	0.688756215	-0.186759272	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:148268|ZNF570; zinc finger protein 570; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; BolA-like protein"	Zinc finger protein 570 GN=ZNF570 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 570 isoform X1 [Felis catus]
ENSG00000171840(NINJ2)	--	1.076372943	11	0.419227056	4	0.305426	2	1.015674379	10	0.440938122	3	0.27010795	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell adhesion (GO:0007155);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: tissue regeneration (GO:0042246);; 	--	--	--	--	Ninjurin	Ninjurin-2 GN=NINJ2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ninjurin-2 [Elephantulus edwardii]
ENSG00000171843(MLLT3)	--	13.73350372	707	15.81087539	843	12.36011729	792	14.40129136	849	13.52774892	718	12.83191263	853	0.941499933	0.232759995	normal	0.932070521	-0.252483945	normal	0.973192954	0.09857247	normal	0.938716194	0.026016901	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15187|0|nle:100599669|MLLT3; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3; K15187 YEATS domain-containing protein 1/3 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	YEATS family	Protein AF-9 GN=MLLT3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: protein AF-9 isoform X2 [Eptesicus fuscus]
ENSG00000171847(FAM90A1)	--	0.148700116	2	0.072720487	4	0.0176774	0	0.018259631	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc knuckle	Protein FAM90A1 GN=FAM90A1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	Putative protein FAM90A23 [Tupaia chinensis]
ENSG00000171848(RRM2)	--	81.22423526	3866	95.03870363	4564	103.2548976	4887	78.15135414	3791	54.56540245	2598	50.394904	2357	0.99130181	-0.059071736	normal	0.000124643	-0.833952553	normal	1.75E-08	-1.059805863	down	0.01448805	-0.629105583	normal	[F]	Nucleotide transport and metabolism	Biological Process: oxidation-reduction process (GO:0055114);; 	K10808|0|pps:100991344|RRM2; ribonucleotide reductase M2; K10808 ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Glutathione metabolism (ko00480);; p53 signaling pathway (ko04115)	[F]	Nucleotide transport and metabolism	"Ribonucleotide reductase, small chain"	Ribonucleoside-diphosphate reductase subunit M2 GN=RRM2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: ribonucleoside-diphosphate reductase subunit M2 [Oryctolagus cuniculus]
ENSG00000171853(TRAPPC12)	--	24.91701637	1104	25.52184413	966	22.6325525	1017	20.00671162	846	19.49058416	886	17.176594	774	0.673803978	-0.414182152	normal	0.968537463	-0.145904448	normal	0.713645238	-0.401519042	normal	0.063284479	-0.322224895	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Trafficking protein particle complex subunit 12 GN=TRAPPC12 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: trafficking protein particle complex subunit 12 [Orycteropus afer afer]
ENSG00000171858(RPS21)	--	1573.20998	2341	1580.42233	2502	1598.76989	2613	1892.56417	3351	1657.39781	2499	1501.557672	2388	0.446161925	0.486366428	normal	0.988387362	-0.023143449	normal	0.983651081	-0.138112084	normal	0.689741201	0.12169285	normal	--	--	--	K02971|2.54137e-62|pps:100988865|RPS21; ribosomal protein S21; K02971 small subunit ribosomal protein S21e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S21e	40S ribosomal protein S21 GN=RPS21 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S21 isoform 1 [Dasypus novemcinctus]
ENSG00000171860(C3AR1)	--	0	0	0.0321179	1	0.217911234	0	0.03201888	1	0.031273754	0	0.031851781	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04009|0|hsa:719|C3AR1, AZ3B, C3AR, HNFAG09; complement component 3a receptor 1; K04009 C3a anaphylatoxin chemotactic receptor (A)"	Neuroactive ligand-receptor interaction (ko04080);; Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	C3a anaphylatoxin chemotactic receptor GN=C3AR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C3a anaphylatoxin chemotactic receptor [Pteropus alecto] 
ENSG00000171861(MRM3)	--	13.9823	479	13.3304	469	13.94890001	488	18.2352	634	19.412	662	16.5344	567	0.787924684	0.372583277	normal	0.493516587	0.474523074	normal	0.946098864	0.20757885	normal	0.073734353	0.354163684	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; Molecular Function: RNA methyltransferase activity (GO:0008173);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	SpoU rRNA Methylase family;; RNA 2'-O ribose methyltransferase substrate binding	"rRNA methyltransferase 3, mitochondrial {ECO:0000303|PubMed:25009282} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2"	A	RNA processing and modification	PREDICTED: RNA methyltransferase-like protein 1 [Galeopterus variegatus]
ENSG00000171862(PTEN)	--	15.04728033	1697	16.75392841	1865	15.27127626	1672	18.73738022	2070	17.42103302	2121	21.3632345	2368	0.951927144	0.255602138	normal	0.977518064	0.164017655	normal	0.380814858	0.493425948	normal	0.060499266	0.304639479	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K01110|0|pps:100983152|PTEN; phosphatase and tensin homolog; K01110 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN [EC:3.1.3.16 3.1.3.48 3.1.3.67] (A)"	Inositol phosphate metabolism (ko00562);; FoxO signaling pathway (ko04068);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; p53 signaling pathway (ko04115);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Tight junction (ko04530);; Hepatitis B (ko05161);; Pathways in cancer (ko05200);; MicroRNAs in cancer (ko05206);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Small cell lung cancer (ko05222);; Central carbon metabolism in cancer (ko05230)	[TR]	Signal transduction mechanisms;; General function prediction only	"C2 domain of PTEN tumour-suppressor protein;; Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	"Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN GN=PTEN OS=Homo sapiens (Human) PE=1 SV=1"	V	Defense mechanisms	TPA: TPA_exp: mitochondrial PTENalpha [Orcinus orca]
ENSG00000171863(RPS7)	--	1295.147058	13322	1177.730063	12079	1173.27298	12279	1022.72783	10868	1059.12227	10947	884.21586	9344	0.970782151	-0.324514957	normal	0.993998563	-0.163370526	normal	0.900926638	-0.402315351	normal	0.113298496	-0.295781986	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02993|4.8695e-136|ssc:100736789|40S ribosomal protein S7-like; K02993 small subunit ribosomal protein S7e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S7e	40S ribosomal protein S7 GN=RPS7 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S7 [Odobenus rosmarus divergens]
ENSG00000171865(RNASEH1)	--	32.25542	2210	28.59666	2074	34.30933	2131	23.19535	1630	24.67723	1654	20.20935	1405	0.484524693	-0.469624831	normal	0.873576172	-0.34759872	normal	0.047999102	-0.608715942	normal	0.001276371	-0.473745857	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA-DNA hybrid ribonuclease activity (GO:0004523);; 	K03469|0|ptr:743012|RNASEH1; ribonuclease H1 (EC:3.1.26.4); K03469 ribonuclease HI [EC:3.1.26.4] (A)	DNA replication (ko03030)	[L]	"Replication, recombination and repair"	RNase H;; Caulimovirus viroplasmin	Ribonuclease H1 GN=RNASEH1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	ribonuclease H1 [Ceratotherium simum simum]
ENSG00000171867(PRNP)	--	135.39683	5624	123.3314356	5230	123.5262101	5069	121.6885605	5094	111.0191045	4607	101.0953765	4169	0.988394048	-0.173580043	normal	0.984117201	-0.204346899	normal	0.960834094	-0.290195607	normal	0.230907836	-0.221048174	normal	--	--	Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; 	"K05634|1.63914e-100|hsa:5621|PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30; prion protein; K05634 prion protein (A)"	Prion diseases (ko05020)	--	--	Prion/Doppel alpha-helical domain;; Major prion protein bPrPp - N terminal	Major prion protein (Precursor) GN=PRNP OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	"prion protein, partial [Galeopterus variegatus]"
ENSG00000171872(KLF17)	--	0.122542014	6	0.137496685	9	0.0117776	0	0.47804665	19	0.527313805	17	0.384006763	19	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09211|0|hsa:128209|KLF17, ZNF393, Zfp393; Kruppel-like factor 17; K09211 krueppel-like factor 17 (A)"	--	--	--	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 17 GN=KLF17 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: Krueppel-like factor 17 [Equus przewalskii]
ENSG00000171873(ADRA1D)	--	5.494718	234	5.624694443	264	3.109882024	147	1.560545	70	3.98806655	178	2.344724	104	6.04E-11	-1.749600126	down	0.342052307	-0.585971311	normal	0.769029431	-0.501361085	normal	0.121233733	-0.894515496	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04137|0|hsa:146|ADRA1D, ADRA1, ADRA1A, ADRA1R, ALPHA1, DAR, dJ779E11.2; adrenoceptor alpha 1D; K04137 adrenergic receptor alpha-1D (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Neuroactive ligand-receptor interaction (ko04080);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Salivary secretion (ko04970)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Alpha-1D adrenergic receptor GN=ADRA1D OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: alpha-1D adrenergic receptor [Ceratotherium simum simum]
ENSG00000171877(FRMD5)	--	2.630499245	218	3.034307279	259	3.070474738	269	3.877631811	371	4.97377658	423	4.700871406	425	0.024756277	0.732260225	normal	0.048446396	0.683128684	normal	0.076670879	0.64863961	normal	0.001038902	0.687887553	normal	--	--	--	--	--	--	--	FERM N-terminal domain;; FERM central domain;; FERM adjacent (FA);; FERM C-terminal PH-like domain	FERM domain-containing protein 5 GN=FRMD5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: FERM domain-containing protein 5 isoform X1 [Erinaceus europaeus]
ENSG00000171885(AQP4)	--	0.165203865	3	0.06185958	5	0.024855647	1	0.012209423	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K09866|0|hsa:361|AQP4, HMIWC2, MIWC; aquaporin 4; K09866 aquaporin-4 (A)"	Vasopressin-regulated water reabsorption (ko04962);; Bile secretion (ko04976)	[G]	Carbohydrate transport and metabolism	Major intrinsic protein	Aquaporin-4 GN=AQP4 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-4 isoform X1 [Tupaia chinensis]
ENSG00000171903(CYP4F11)	--	0.132994871	7	0.14179488	8	0.037656376	1	0.451361824	24	0.608818365	33	0.233742072	13	0.661531178	1.553718759	normal	0.085035307	1.839992586	normal	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17729|0|hsa:57834|CYP4F11, CYPIVF11; cytochrome P450, family 4, subfamily F, polypeptide 11 (EC:1.14.13.194); K17729 cytochrome P450, family 4, subfamily F, polypeptide 11 [EC:1.14.14.1 1.14.13.194] (A)"	--	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Phylloquinone omega-hydroxylase CYP4F11 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: leukotriene-B(4) omega-hydroxylase 1 isoform X2 [Ursus maritimus]
ENSG00000171914(TLN2)	--	3.99892631	950	3.6671578	929	4.563862859	1082	3.361950363	715	3.571405458	716	3.565800202	798	0.581712168	-0.439993127	normal	0.736398334	-0.396408229	normal	0.555985223	-0.446801217	normal	0.00865861	-0.430295407	normal	--	--	Cellular Component: ruffle (GO:0001726);; Molecular Function: actin binding (GO:0003779);; Molecular Function: structural constituent of cytoskeleton (GO:0005200);; Cellular Component: focal adhesion (GO:0005925);; Biological Process: cytoskeletal anchoring at plasma membrane (GO:0007016);; 	"K06271|0|hsa:83660|TLN2, ILWEQ; talin 2; K06271 talin (A)"	Rap1 signaling pathway (ko04015);; Focal adhesion (ko04510);; Platelet activation (ko04611);; HTLV-I infection (ko05166)	[Z]	Cytoskeleton	"Talin, middle domain;; Vinculin Binding Site;; I/LWEQ domain;; FERM N-terminal domain;; FERM central domain;; PTB domain (IRS-1 type)"	Talin-2 GN=TLN2 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: talin-2 isoform 2 [Odobenus rosmarus divergens]
ENSG00000171916(LGALS9C)	--	0.145482589	1	0	0	0.274064351	1	0	0	0.036605906	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: carbohydrate binding (GO:0030246);; 	"K10093|0|hsa:654346|LGALS9C; lectin, galactoside-binding, soluble, 9C; K10093 galectin-9 (A)"	--	[W]	Extracellular structures	Galactoside-binding lectin	Galectin-9C GN=LGALS9C OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: galectin-9 isoform X2 [Camelus dromedarius]
ENSG00000171928(TVP23B)	--	48.77875401	1100	51.5700309	1247	50.58812	1161	42.45055491	1044	39.04104071	926	43.40156209	1041	0.975902979	-0.106061981	normal	0.561658811	-0.450167833	normal	0.968305564	-0.165461612	normal	0.183551956	-0.241703029	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Eukaryotic protein of unknown function (DUF846)	Golgi apparatus membrane protein TVP23 homolog B GN=TVP23B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Golgi apparatus membrane protein TVP23 homolog B isoform X1 [Galeopterus variegatus]
ENSG00000171931(FBXW10)	--	0.58654818	43	0.20672521	15	0.518330514	38	0.75024309	56	0.693331414	51	0.722055403	53	0.964571556	0.339600691	normal	0.014713319	1.64897832	normal	0.950606063	0.456262325	normal	0.193411701	0.716263618	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10266|0|hsa:10517|FBXW10, Fbw10, HREP, SM25H2, SM2SH2, C17orf1, C17orf1A; F-box and WD repeat domain containing 10; K10266 F-box and WD-40 domain protein 10 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat"	F-box/WD repeat-containing protein 10 GN=FBXW10 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	F-box/WD repeat-containing protein 10 [Pteropus alecto]
ENSG00000171940(ZNF217)	--	23.93602	2228	33.47903375	3160	29.69831877	2741	23.14647304	2131	20.54309854	2070	29.4082351	2757	0.985248826	-0.094983918	normal	0.036052991	-0.63134406	normal	0.989569911	0.000105439	normal	0.455886474	-0.244886673	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain"	Zinc finger protein 217 GN=ZNF217 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 217 [Galeopterus variegatus]
ENSG00000171943(SRGAP2C)	--	2.936924868	354	2.969943109	377	3.32385081	374	3.300946847	393	2.6925533	311	2.741163851	318	0.962245577	0.119455497	normal	0.897132973	-0.297759131	normal	0.931031429	-0.241243826	normal	0.669140257	-0.134545445	normal	--	--	--	--	--	[Z]	Cytoskeleton	"Fes/CIP4, and EFC/F-BAR homology domain"	SLIT-ROBO Rho GTPase-activating protein 2C GN=SRGAP2C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SLIT-ROBO Rho GTPase-activating protein 2 isoform 2 [Ceratotherium simum simum]
ENSG00000171951(SCG2)	--	1.183729397	68	1.225860516	40	0.929973536	53	0.5141899	24	0.390690119	22	0.277468241	16	0.00638888	-1.474774744	down	0.858820626	-0.840470793	normal	0.010381048	-1.64603232	normal	0.005069131	-1.398964042	down	--	--	Cellular Component: secretory granule (GO:0030141);; 	--	--	--	--	Granin (chromogranin or secretogranin)	Secretoneurin (Precursor) GN=SCG2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: secretogranin-2 [Odobenus rosmarus divergens]
ENSG00000171953(ATPAF2)	--	11.71190607	337	10.06465619	319	10.13146016	290	10.36634439	312	12.50759983	367	13.76359433	364	0.958407051	-0.141364749	normal	0.950176621	0.180001011	normal	0.881650152	0.318110427	normal	0.720299797	0.119937273	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: proton-transporting ATP synthase complex assembly (GO:0043461);; 	"K07556|0|hsa:91647|ATPAF2, ATP12, ATP12p, MC5DN1; ATP synthase mitochondrial F1 complex assembly factor 2; K07556 ATP synthase mitochondrial F1 complex assembly factor 2 (A)"	--	[C]	Energy production and conversion	ATP12 chaperone protein	ATP synthase mitochondrial F1 complex assembly factor 2 (Precursor) GN=ATPAF2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: ATP synthase mitochondrial F1 complex assembly factor 2 isoform X1 [Galeopterus variegatus]
ENSG00000171960(PPIH)	--	22.81347332	211	27.37690509	262	29.7193797	284	32.97051503	321	30.14516019	278	29.66373743	279	0.313423373	0.571104473	normal	0.964631953	0.063734356	normal	0.96711622	-0.033736001	normal	0.544145742	0.192561578	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	K09567|2.96926e-127|umr:103670828|PPIH; peptidylprolyl isomerase H (cyclophilin H); K09567 peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8] (A)	Spliceosome (ko03040)	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase H GN=PPIH OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase H isoform X1 [Bos taurus] 
ENSG00000171962(DRC3)	--	0.7341313	27	0.789669805	20	0.84810421	20	0.383555006	12	1.3742865	14	0.236369732	10	0.86583497	-1.104208068	normal	0.982945439	-0.49137863	normal	0.961787956	-0.909441835	normal	0.210376342	-0.917948299	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine Rich repeats (2 copies);; Leucine-rich repeat;; Leucine rich repeat;; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 48 GN=LRRC48 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat-containing protein 48 [Loxodonta africana]
ENSG00000171970(ZNF57)	--	1.368605504	51	1.205912136	51	1.306913176	56	0.94447263	41	1.309949622	54	1.71067831	58	0.967407472	-0.334443517	normal	0.976697268	0.059325917	normal	0.976995126	0.041240269	normal	0.948324746	-0.066345532	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:126295|ZNF57, ZNF424; zinc finger protein 57; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Probable zinc-binding domain;; Uncharacterized protein conserved in bacteria (DUF2321)"	Zinc finger protein 57 GN=ZNF57 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 555-like isoform X1 [Mustela putorius furo]
ENSG00000171984(C20orf196)	--	3.435289368	40	7.004945602	66	4.793169796	64	3.560547925	39	6.074637696	97	4.880575026	57	0.981732222	-0.064835869	normal	0.844888777	0.524131452	normal	0.972393098	-0.171114495	normal	0.878142483	0.163366112	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF4521)	Uncharacterized protein C20orf196 GN=C20orf196 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C20orf196 homolog [Galeopterus variegatus]
ENSG00000171988(JMJD1C)	--	5.442313075	862	6.863619062	1132	6.531703268	1006	8.155626	1290	8.21896623	1368	8.02689616	1301	0.160163842	0.549972867	normal	0.943609949	0.251461745	normal	0.818472648	0.362219142	normal	0.018017095	0.379001246	normal	--	--	--	K11449|0|mcf:102143079|JMJD1C; jumonji domain containing 1C; K11449 jumonji domain-containing protein 1C [EC:1.14.11.-] (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	"JmjC domain, hydroxylase"	Probable JmjC domain-containing histone demethylation protein 2C GN=JMJD1C OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: probable JmjC domain-containing histone demethylation protein 2C isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000171989(LDHAL6B)	--	0.359601	10	0.464803	13	0.783888	21	0.356029	10	0.243707	6	0.605443	17	--	--	--	--	--	--	0.986993543	-0.289903763	normal	--	--	--	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00016|0|hsa:92483|LDHAL6B, LDH6B, LDHAL6, LDHL; lactate dehydrogenase A-like 6B (EC:1.1.1.27); K00016 L-lactate dehydrogenase [EC:1.1.1.27] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Cysteine and methionine metabolism (ko00270);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640)	[C]	Energy production and conversion	"lactate/malate dehydrogenase, NAD binding domain;; lactate/malate dehydrogenase, alpha/beta C-terminal domain"	L-lactate dehydrogenase A-like 6B GN=LDHAL6B OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: L-lactate dehydrogenase A-like 6B-like [Tupaia chinensis]
ENSG00000171992(SYNPO)	--	22.74607	2599	21.7845453	2524	23.474911	2726	30.55713866	3503	29.69020689	3418	34.63725105	4009	0.798192282	0.399597969	normal	0.763287044	0.415799107	normal	0.193977081	0.547913256	normal	0.002118094	0.45702475	normal	--	--	--	--	--	--	--	Calcineurin-binding protein (Calsarcin)	Synaptopodin GN=SYNPO OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: synaptopodin [Camelus ferus]
ENSG00000172006(ZNF554)	--	0.512747367	23	0.429482332	24	0.6560379	36	0.362489706	20	0.49630232	27	0.343261334	19	0.987064836	-0.216913067	normal	0.984910221	0.140168243	normal	0.877168572	-0.878693504	normal	0.683467759	-0.350997903	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:115196|ZNF554; zinc finger protein 554; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 554 GN=ZNF554 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 554 [Equus caballus]
ENSG00000172007(RAB33B)	--	2.324988426	146	2.180555362	138	2.457199834	151	2.798064171	178	2.780093	177	2.62495635	167	0.939181451	0.252665502	normal	0.903939177	0.334411513	normal	0.961110546	0.135715182	normal	0.542395782	0.241792196	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07920|6.64109e-153|ecb:100063290|RAB33B; RAB33B, member RAS oncogene family; K07920 Ras-related protein Rab-33B (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase;; Signal recognition particle receptor beta subunit	Ras-related protein Rab-33B GN=RAB33B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-33B [Equus caballus] 
ENSG00000172009(THOP1)	--	35.8105581	1262	39.9246736	1457	42.6358726	1533	42.106769	1440	37.16960111	1342	38.24388681	1348	0.972536447	0.159342942	normal	0.975579982	-0.139891415	normal	0.966946581	-0.193624796	normal	0.802027024	-0.063217188	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K01392|0|hsa:7064|THOP1, EP24.15, MEPD_HUMAN, MP78, TOP; thimet oligopeptidase 1 (EC:3.4.24.15); K01392 thimet oligopeptidase [EC:3.4.24.15] (A)"	Renin-angiotensin system (ko04614);; African trypanosomiasis (ko05143)	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M3	Thimet oligopeptidase GN=THOP1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thimet oligopeptidase [Myotis davidii] 
ENSG00000172014(ANKRD20A4)	--	0.12240647	10	0.084964461	7	0.219047187	17	0.120874027	10	0.061350051	4	0.075447534	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	CCDC144C protein coiled-coil region;; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 20A4 GN=ANKRD20A4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like isoform X4 [Bos taurus]
ENSG00000172020(GAP43)	--	0.092763065	4	0	0	0	0	0.023290308	1	0.04299251	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of growth (GO:0040008);; 	--	--	--	--	Neuromodulin;; Gap junction protein N-terminal region;; IQ calmodulin-binding motif	Neuromodulin GN=GAP43 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: neuromodulin [Panthera tigris altaica]
ENSG00000172031(EPHX4)	--	0.753523	14	0.957891	18	0.843899	15	1.00776	19	1.30794	24	1.17162	22	--	--	--	0.98298743	0.366848186	normal	0.981824864	0.5022298	normal	--	--	--	[R]	General function prediction only	--	--	--	[I]	Lipid transport and metabolism	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Ndr family	Epoxide hydrolase 4 GN=EPHX4 OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: epoxide hydrolase 4 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000172037(LAMB2)	--	24.03122553	2865	26.132944	3057	22.08699345	2693	16.91454817	2006	16.83886696	1987	17.83064215	2126	0.183520158	-0.544694638	normal	0.027388268	-0.642553708	normal	0.881263429	-0.34914287	normal	0.000360098	-0.514760024	normal	--	--	--	"K06243|0|hsa:3913|LAMB2, LAMS, NPHS5; laminin, beta 2 (laminin S); K06243 laminin, beta 2 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin N-terminal (Domain VI)	Laminin subunit beta-2 (Precursor) GN=LAMB2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: laminin subunit beta-2 isoform X1 [Equus caballus]
ENSG00000172046(USP19)	--	12.80531761	1153	10.34864069	1043	10.8114245	1096	9.302677216	926	10.73018064	1048	11.33473715	1124	0.842392114	-0.346624042	normal	0.979534383	-0.014506017	normal	0.980528408	0.028064556	normal	0.63570135	-0.108197165	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11847|0|hsa:10869|USP19, ZMYND9; ubiquitin specific peptidase 19 (EC:3.4.19.12); K11847 ubiquitin carboxyl-terminal hydrolase 19 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; CS domain;; MYND finger	Ubiquitin carboxyl-terminal hydrolase 19 GN=USP19 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 19 isoform X4 [Canis lupus familiaris]
ENSG00000172053(QARS)	--	94.62603066	2342	90.56731276	2047	97.70387428	2229	87.99220289	2132	98.87399051	2320	95.44064018	2345	0.979099629	-0.166251529	normal	0.979455701	0.1590767	normal	0.987036184	0.06485696	normal	0.957292879	0.017679446	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: glutamine-tRNA ligase activity (GO:0004819);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; Biological Process: glutaminyl-tRNA aminoacylation (GO:0006425);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	K01886|0|rno:100911132|glutamine--tRNA ligase-like; K01886 glutaminyl-tRNA synthetase [EC:6.1.1.18] (A)	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (E and Q), catalytic domain;; Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1;; tRNA synthetases class I (E and Q), anti-codon binding domain;; Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2"	Glutamine--tRNA ligase GN=QARS OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: glutamine--tRNA ligase [Galeopterus variegatus]
ENSG00000172058(SERF1A)	--	1.221513	14	0.753248	10	0.7384963	7	0.859373	10	0.741689009	8	0.834864	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	4F5 protein family	Small EDRK-rich factor 1 GN=SERF1B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: small EDRK-rich factor 1-like [Elephantulus edwardii]
ENSG00000172059(KLF11)	--	7.159265076	482	6.906320687	464	7.678689243	434	2.606532258	175	2.19693824	144	3.411639987	229	1.12E-11	-1.484307516	down	2.32E-14	-1.698958666	down	0.000253786	-0.926119613	normal	4.06E-12	-1.35300349	down	[R]	General function prediction only	--	K09209|0|nle:100607386|KLF11; Kruppel-like factor 11; K09209 krueppel-like factor 10/11 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Krueppel-like factor 11 GN=KLF11 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: Krueppel-like factor 11 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000172061(LRRC15)	--	0.138287121	13	0.051573326	3	0.05244069	5	0.04451494	5	0.03436928	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat;; Leucine-rich repeat	Leucine-rich repeat-containing protein 15 (Precursor) GN=LRRC15 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 15 [Oryctolagus cuniculus]
ENSG00000172062(SMN1)	--	3.838396	116	6.372889019	187	8.441982001	248	6.545694	196	8.000417019	236	7.239400019	209	0.154069735	0.718499678	normal	0.90207223	0.312071183	normal	0.930748326	-0.253442951	normal	0.723241561	0.19821078	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: mRNA processing (GO:0006397);; 	K13129|3.61946e-118|pps:100984482|SMN1; survival motor neuron protein; K13129 survival motor neuron protein (A)	RNA transport (ko03013)	[A]	RNA processing and modification	Survival motor neuron protein (SMN)	Survival motor neuron protein GN=SMN2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: survival of motor neuron protein-like isoform X1 [Panthera tigris altaica] 
ENSG00000172071(EIF2AK3)	--	5.838095914	504	6.577944481	578	6.236705456	542	5.640135265	494	5.287227423	452	6.474807505	568	0.970118296	-0.059561547	normal	0.789960033	-0.375060487	normal	0.971365574	0.059145419	normal	0.653965111	-0.122026302	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08860|0|hsa:9451|EIF2AK3, PEK, PERK, WRS; eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1); K08860 eukaryotic translation initiation factor 2-alpha kinase 3 [EC:2.7.11.1] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[J]	"Translation, ribosomal structure and biogenesis"	Protein kinase domain;; Protein tyrosine kinase;; PQQ enzyme repeat	Eukaryotic translation initiation factor 2-alpha kinase 3 (Precursor) GN=EIF2AK3 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 2-alpha kinase 3 [Equus przewalskii]
ENSG00000172081(MOB3A)	--	8.941109466	478	7.35428928	442	7.44811251	449	6.743807298	375	5.059590347	295	6.0124048	350	0.784488568	-0.379570893	normal	0.154500011	-0.602217569	normal	0.813009492	-0.366251023	normal	0.035169427	-0.446087959	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mob1/phocein family	MOB kinase activator 3A GN=MOB3A OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: MOB kinase activator 3A [Myotis davidii]
ENSG00000172086(KRCC1)	--	6.741439288	215	9.10212751	285	6.986694506	219	8.18676754	264	8.909939796	287	7.998860296	257	0.925411964	0.2636663	normal	0.966563127	-0.011278106	normal	0.941354568	0.221135048	normal	0.677980916	0.146855757	normal	--	--	--	--	--	--	--	--	Lysine-rich coiled-coil protein 1 GN=KRCC1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: lysine-rich coiled-coil protein 1 [Tupaia chinensis]
ENSG00000172113(NME6)	--	8.948698268	372	11.15220478	360	9.082434055	352	10.0136595	411	13.44298556	459	12.01012126	436	0.963420343	0.112561116	normal	0.866149988	0.327848404	normal	0.894156265	0.299303796	normal	0.321860452	0.247759244	normal	[F]	Nucleotide transport and metabolism	--	K00940|1.43531e-142|pps:100983985|NME6; NME/NM23 nucleoside diphosphate kinase 6; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	Nucleoside diphosphate kinase	Nucleoside diphosphate kinase 6 GN=NME6 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: nucleoside diphosphate kinase 6 isoform 1 [Ceratotherium simum simum] 
ENSG00000172115(CYCS)	--	86.2864	3018	92.48682	3372	109.8502	3557	102.069	3714	86.5185	2916	78.0943004	2722	0.961807781	0.268425387	normal	0.972524218	-0.230928887	normal	0.81476415	-0.39409322	normal	0.685055732	-0.111019036	normal	[C]	Energy production and conversion	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: heme binding (GO:0020037);; 	"K08738|2.81758e-71|ptr:744779|CYCS; cytochrome c, somatic; K08738 cytochrome c (A)"	Sulfur metabolism (ko00920);; p53 signaling pathway (ko04115);; Apoptosis (ko04210);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Small cell lung cancer (ko05222);; Viral myocarditis (ko05416)	[C]	Energy production and conversion	"Cytochrome c;; Cytochrome C oxidase, cbb3-type, subunit III"	Cytochrome c GN=CYCS OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: cytochrome c [Loxodonta africana] 
ENSG00000172123(SLFN12)	--	0.097235183	4	0.024256293	1	0	0	0	0	0.16565583	6	0.104472455	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	Divergent AAA domain	Schlafen family member 12 GN=SLFN12 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: schlafen family member 12 [Physeter catodon]
ENSG00000172137(CALB2)	--	1.329790294	37	0.483733304	15	1.079535708	33	4.166566002	129	5.305798972	159	1.676812701	52	6.00E-07	1.730120276	up	0	3.260727507	up	0.907963938	0.62476747	normal	0.026313539	1.977644429	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain;; EF-hand domain pair;; EF hand;; EF-hand domain pair	Calretinin GN=CALB2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calretinin [Equus caballus] 
ENSG00000172139(SLC9C1)	--	0	0	0	0	0	0	0	0	0	0	0.032657671	2	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14726|0|hsa:285335|SLC9C1, NHE, SLC9A10, sperm-NHE; solute carrier family 9, subfamily C (Na+-transporting carboxylic acid decarboxylase), member 1; K14726 solute carrier family 9 (sodium/hydrogen exchanger), member 10/11 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family;; Cyclic nucleotide-binding domain	Sodium/hydrogen exchanger 10 GN=SLC9C1 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 10 [Ursus maritimus]
ENSG00000172159(FRMD3)	--	2.320395615	211	1.895368988	168	2.501221612	224	1.724677441	158	1.195209507	108	1.0912853	99	0.77122893	-0.444396495	normal	0.371688684	-0.651480136	normal	4.51E-05	-1.174035422	down	0.009339308	-0.746660421	normal	--	--	--	--	--	[R]	General function prediction only	FERM N-terminal domain;; FERM C-terminal PH-like domain;; FERM central domain;; FERM adjacent (FA)	FERM domain-containing protein 3 GN=FRMD3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: FERM domain-containing protein 3 isoform X1 [Equus caballus]
ENSG00000172164(SNTB1)	--	3.59927373	253	4.8473651	354	3.85250097	255	2.42834459	183	2.47776038	171	6.07506261	443	0.61806755	-0.494577254	normal	3.07E-05	-1.064487363	down	0.005541268	0.784942465	normal	0.904901829	-0.131946756	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	PDZ domain (Also known as DHR or GLGF);; PH domain	Beta-1-syntrophin GN=SNTB1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: beta-1-syntrophin [Ceratotherium simum simum]
ENSG00000172167(MTBP)	--	4.9674	220	4.996749047	233	7.364613	320	4.38324	187	4.16072	205	3.542778	194	0.929345237	-0.263300307	normal	0.945347396	-0.204714911	normal	0.038505986	-0.725854467	normal	0.132961846	-0.41996693	normal	--	--	--	--	--	--	--	MDM2-binding;; MDM2-binding;; MDM2-binding	Mdm2-binding protein GN=MTBP OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: mdm2-binding protein [Equus caballus]
ENSG00000172171(TEFM)	--	8.19229	247	7.60475	230	9.09023	274	11.27542	345	8.66198	262	10.12873	307	0.668120283	0.448880997	normal	0.953072459	0.165486372	normal	0.956002592	0.154962923	normal	0.360366932	0.261979017	normal	--	--	--	"K17658|0|hsa:79736|TEFM, C17orf42; transcription elongation factor, mitochondrial; K17658 transcription elongation factor, mitochondrial (A)"	--	--	--	Helix-hairpin-helix motif	"Transcription elongation factor, mitochondrial (Precursor) GN=TEFM OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: transcription elongation factor, mitochondrial isoform X1 [Leptonychotes weddellii]"
ENSG00000172172(MRPL13)	--	34.04890266	551	34.06090217	557	37.3452034	607	44.98302639	743	41.99310216	676	38.051851	622	0.720627911	0.399515236	normal	0.925282142	0.257284453	normal	0.973714255	0.026860512	normal	0.282052368	0.229498464	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02871|9.37884e-131|hsa:28998|MRPL13, L13, L13A, L13mt, RPL13, RPML13; mitochondrial ribosomal protein L13; K02871 large subunit ribosomal protein L13 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L13	"39S ribosomal protein L13, mitochondrial GN=MRPL13 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L13, mitochondrial [Ceratotherium simum simum]"
ENSG00000172175(MALT1)	--	9.111376058	691	8.748426027	753	8.382556851	742	12.7424138	1031	15.23672028	1307	11.09925242	966	0.182070266	0.545455658	normal	0.001266084	0.772918465	normal	0.789441677	0.371646869	normal	0.00475676	0.574726056	normal	[R]	General function prediction only	--	"K07369|0|hsa:10892|MALT1, IMD12, MLT, MLT1; MALT1 paracaspase (EC:3.4.22.-); K07369 mucosa-associated lymphoid tissue lymphoma translocation protein 1 [EC:3.4.22.-] (A)"	NF-kappa B signaling pathway (ko04064);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Tuberculosis (ko05152)	--	--	Immunoglobulin domain;; Caspase domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain	Mucosa-associated lymphoid tissue lymphoma translocation protein 1 GN=MALT1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000172179(PRL)	--	0	0	0	0	0	0	0.050594309	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05439|1.83739e-156|hsa:5617|PRL; prolactin; K05439 prolactin (A)	Cytokine-cytokine receptor interaction (ko04060);; Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917)	--	--	Somatotropin hormone family	Prolactin (Precursor) GN=PRL OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: prolactin isoform X1 [Sus scrofa]
ENSG00000172183(ISG20)	--	5.038922552	110	3.661188696	93	5.581747056	106	3.854699066	77	3.472723339	66	4.429808923	92	0.80138324	-0.536399137	normal	0.863828252	-0.50636696	normal	0.959573783	-0.209439782	normal	0.356515721	-0.415550334	normal	[L]	"Replication, recombination and repair"	--	K12579|7.95279e-119|pps:100969307|ISG20; interferon stimulated exonuclease gene 20kDa; K12579 interferon-stimulated gene 20 kDa protein [EC:3.1.13.1] (A)	--	[L]	"Replication, recombination and repair"	Exonuclease	Interferon-stimulated gene 20 kDa protein GN=ISG20 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	interferon-stimulated gene 20 kDa protein [Sus scrofa] 
ENSG00000172197(MBOAT1)	--	4.311654279	90	2.072576	71	4.853979	71	2.608958	85	3.44694434	85	2.422909571	72	0.969916678	-0.111338179	normal	0.960662121	0.233663708	normal	0.974441866	0.011640233	normal	0.967635723	0.039077019	normal	--	--	--	"K13517|0|hsa:154141|MBOAT1, 1, LPEAT1, LPLAT, LPLAT_1, LPSAT, OACT1, dJ434O11.1; membrane bound O-acyltransferase domain containing 1 (EC:2.3.1.n6); K13517 lysophospholipid acyltransferase 1/2 [EC:2.3.1.51 2.3.1.-] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[S]	Function unknown	"MBOAT, membrane-bound O-acyltransferase family"	Lysophospholipid acyltransferase 1 GN=MBOAT1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: lysophospholipid acyltransferase 1 [Camelus ferus] 
ENSG00000172201(ID4)	--	0.0332308	1	0.12906	4	0.0318321	0	0.0324133	1	0.063741	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K17695|3.12426e-58|rno:291023|Id4, Idb4; inhibitor of DNA binding 4; K17695 DNA-binding protein inhibitor ID4 (A)"	TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	--	--	Helix-loop-helix DNA-binding domain	DNA-binding protein inhibitor ID-4 GN=ID4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-binding protein inhibitor ID-4 [Loxodonta africana]
ENSG00000172209(GPR22)	--	0	0	0.0465073	2	0	0	0	0	0.0441743	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04319|0|ptr:744517|GPR22; G protein-coupled receptor 22; K04319 G protein-coupled receptor 22 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 22 GN=GPR22 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 22 [Ursus maritimus] 
ENSG00000172215(CXCR6)	--	0.145826	7	0	0	0.0642561	1	0.0417722	2	0.122458	5	0.062359702	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04191|0|hsa:10663|CXCR6, BONZO, CD186, STRL33, TYMSTR; chemokine (C-X-C motif) receptor 6; K04191 C-X-C chemokine receptor type 6 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	C-X-C chemokine receptor type 6 GN=CXCR6 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: c-X-C chemokine receptor type 6 [Ceratotherium simum simum]
ENSG00000172216(CEBPB)	--	165.043	4365	158.423	4274	136.956	3815	128.908	3462	128.038	3447	221.479	5985	0.887907327	-0.365063525	normal	0.929629004	-0.331541256	normal	0.028989569	0.641172152	normal	0.971868697	0.030338158	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10048|1.17407e-155|ptr:469969|CEBPB; CCAAT/enhancer binding protein (C/EBP), beta; K10048 CCAAT/enhancer binding protein (C/EBP), beta (A)"	TNF signaling pathway (ko04668);; Tuberculosis (ko05152);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Basic region leucine zipper;; bZIP transcription factor	CCAAT/enhancer-binding protein beta GN=CEBPB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CCAAT/enhancer-binding protein beta [Ochotona princeps]
ENSG00000172232(AZU1)	--	1.235519708	47	1.974581648	73	1.108764332	45	0.40379097	16	1.163556806	37	0.356966756	10	0.063861332	-1.497704462	normal	0.277047363	-0.972947982	normal	0.002661644	-2.022049417	down	0.021223394	-1.411118275	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin	Azurocidin (Precursor) GN=AZU1 OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: azurocidin [Ovis aries]
ENSG00000172238(ATOH1)	--	0.0559631	2	0	0	0	0	0.055096	2	0	0	0.0274164	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09083|0|hsa:474|ATOH1, ATH1, HATH1, MATH-1, bHLHa14; atonal homolog 1 (Drosophila); K09083 atonal protein 1/7 (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Protein atonal homolog 1 GN=ATOH1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: protein atonal homolog 1 [Leptonychotes weddellii]
ENSG00000172239(PAIP1)	--	54.86208799	2141	61.16718604	2421	58.2113288	2208	57.2143793	2143	65.31639299	2240	56.75450168	2126	0.987283814	-0.029464075	normal	0.982978135	-0.133444217	normal	0.986603877	-0.062846148	normal	0.739936328	-0.07798816	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; 	K14322|0|hsa:10605|PAIP1; poly(A) binding protein interacting protein 1; K14322 polyadenylate-binding protein-interacting protein 1 (A)	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	MIF4G domain;; Ataxin-2 C-terminal region	Polyadenylate-binding protein-interacting protein 1 GN=PAIP1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: polyadenylate-binding protein-interacting protein 1 isoform 5 [Canis lupus familiaris]
ENSG00000172244(C5orf34)	--	3.85364505	166	3.809070725	168	4.5391794	182	3.3045257	135	2.841937	120	2.986564295	128	0.913175309	-0.32570622	normal	0.728253764	-0.501485291	normal	0.687639559	-0.510996551	normal	0.182243311	-0.451269987	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4524);; Domain of unknown function (DUF4520)	Uncharacterized protein C5orf34 GN=C5orf34 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C5orf34 homolog [Ceratotherium simum simum]
ENSG00000172247(C1QTNF4)	--	0.0491857	1	0.0966652	2	0	0	0	0	0.0934163	1	0.191328	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain	Complement C1q tumor necrosis factor-related protein 4 (Precursor) GN=C1QTNF4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: complement C1q tumor necrosis factor-related protein 4 [Canis lupus familiaris]
ENSG00000172262(ZNF131)	--	7.755742665	492	9.193372343	587	7.351466135	451	9.154149088	538	9.40062719	601	8.55103503	571	0.96751987	0.097823411	normal	0.972862896	0.012545987	normal	0.857762107	0.331083053	normal	0.593803359	0.139147983	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein 131 GN=ZNF131 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 131 isoform X1 [Mustela putorius furo] 
ENSG00000172264(MACROD2)	--	0.531953596	26	0.27375	7	0.66484221	27	0.381957	19	0.196529234	17	0.863768661	29	0.979914805	-0.451974197	normal	--	--	--	0.985173299	0.089940473	normal	0.958484282	0.096680943	normal	[R]	General function prediction only	--	--	--	[BK]	Chromatin structure and dynamics;; Transcription	Macro domain	O-acetyl-ADP-ribose deacetylase MACROD2 GN=MACROD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: O-acetyl-ADP-ribose deacetylase MACROD2-like [Myotis lucifugus]
ENSG00000172269(DPAGT1)	--	24.49119	734	22.788912	674	21.13217997	635	27.39588538	802	27.41071	817	32.39883859	979	0.972361325	0.096796042	normal	0.929403949	0.255639281	normal	0.05343277	0.615072146	normal	0.07293968	0.325946987	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: phospho-N-acetylmuramoyl-pentapeptide-transferase activity (GO:0008963);; Cellular Component: integral component of membrane (GO:0016021);; 	"K01001|0|hsa:1798|DPAGT1, ALG7, CDG-Ij, CDG1J, CMSTA2, D11S366, DGPT, DPAGT, DPAGT2, G1PT, GPT, UAGT, UGAT; dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (EC:2.7.8.15); K01001 UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase [EC:2.7.8.15] (A)"	N-Glycan biosynthesis (ko00510)	[G]	Carbohydrate transport and metabolism	Glycosyl transferase family 4	UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase GN=DPAGT1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase isoform 1 [Ceratotherium simum simum] 
ENSG00000172270(BSG)	--	338.7806835	8641	325.8251969	8472	311.052105	8089	314.61785	8166	316.8728141	8049	321.1577429	8269	0.994385011	-0.112380418	normal	0.994522781	-0.095302136	normal	0.995515558	0.023455729	normal	0.817059731	-0.062950605	normal	--	--	--	"K06535|0|hsa:682|BSG, 5F7, CD147, EMMPRIN, M6, OK, TCSF; basigin (Ok blood group); K06535 basigin (A)"	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Basigin (Precursor) GN=BSG OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: basigin isoform X1 [Orycteropus afer afer]
ENSG00000172273(HINFP)	--	3.73900234	158	4.489052976	187	3.282612383	180	4.071630022	185	4.124203017	200	6.897342294	271	0.951860647	0.195014627	normal	0.963731019	0.074949031	normal	0.352139033	0.578020169	normal	0.363889618	0.301373278	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Histone H4 transcription factor GN=HINFP OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: histone H4 transcription factor [Ailuropoda melanoleuca] 
ENSG00000172292(CERS6)	--	20.24979	2347	19.866491	2295	19.24049	2175	11.6294	1347	10.48534479	1212	10.97647	1263	0.000102694	-0.831172068	normal	4.21E-06	-0.941661937	normal	0.000373114	-0.791720712	normal	2.73E-10	-0.856341765	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: DNA binding (GO:0003677);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04710|0|ptr:741293|CERS6, LASS6; ceramide synthase 6; K04710 ceramide synthetase [EC:2.3.1.24] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TLC domain;; Homeobox domain	Ceramide synthase 6 GN=CERS6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ceramide synthase 6 isoform X1 [Galeopterus variegatus]
ENSG00000172296(SPTLC3)	--	0.175937805	16	0.144376331	15	0.197244872	10	0.454251164	20	0.464143953	33	0.659364172	18	--	--	--	0.815971711	1.043594284	normal	--	--	--	--	--	--	[H]	Coenzyme transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K00654|0|hsa:55304|SPTLC3, C20orf38, LCB2B, LCB3, SPT3, SPTLC2L, dJ718P11, dJ718P11.1, hLCB2b; serine palmitoyltransferase, long chain base subunit 3 (EC:2.3.1.50); K00654 serine palmitoyltransferase [EC:2.3.1.50] (A)"	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[O]	"Posttranslational modification, protein turnover, chaperones"	Aminotransferase class I and II;; Beta-eliminating lyase	Serine palmitoyltransferase 3 GN=SPTLC3 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine palmitoyltransferase 3 [Galeopterus variegatus]
ENSG00000172301(COPRS)	--	53.140792	838	73.584316	1196	67.10410072	1103	66.41717921	1079	52.1047014	814	70.278615	1123	0.860823182	0.333300729	normal	0.116215992	-0.575655101	normal	0.980728581	0.017609766	normal	0.858329622	-0.077866692	normal	--	--	Cellular Component: nucleus (GO:0005634);; Molecular Function: histone binding (GO:0042393);; Biological Process: histone H4-R3 methylation (GO:0043985);; 	--	--	--	--	Cooperator of PRMT5 family	Coordinator of PRMT5 and differentiation stimulator GN=COPRS OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: coordinator of PRMT5 and differentiation stimulator [Odobenus rosmarus divergens]
ENSG00000172318(B3GALT1)	--	0.458386	36	0.586776	46	0.753941	58	0.215426	17	0.271664	21	0.151566	12	0.768648386	-1.046849964	normal	0.499370458	-1.097953961	normal	7.52E-05	-2.146637731	down	0.004110075	-1.506727051	down	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K07819|0|umr:103659526|B3GALT1; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1; K07819 beta-1,3-galactosyltransferase 1 [EC:2.4.1.-] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"Beta-1,3-galactosyltransferase 1 GN=B3GALT1 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyltransferase 1 [Leptonychotes weddellii]"
ENSG00000172331(BPGM)	--	11.63739874	315	11.19624355	307	10.59984061	285	11.67362475	321	14.04809438	380	9.649248636	264	0.968100747	-0.003593433	normal	0.906320586	0.285069993	normal	0.961217275	-0.118064331	normal	0.86178335	0.067687363	normal	[G]	Carbohydrate transport and metabolism	--	"K01837|0|hsa:669|BPGM, DPGM; 2,3-bisphosphoglycerate mutase (EC:3.1.3.13 5.4.2.4 5.4.2.11); K01837 bisphosphoglycerate mutase [EC:5.4.2.4 5.4.2.11 3.1.3.13] (A)"	"Glycolysis / Gluconeogenesis (ko00010);; Glycine, serine and threonine metabolism (ko00260)"	[G]	Carbohydrate transport and metabolism	Histidine phosphatase superfamily (branch 1)	Bisphosphoglycerate mutase GN=BPGM OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	bisphosphoglycerate mutase [Oryctolagus cuniculus] 
ENSG00000172336(POP7)	--	46.52434695	635	40.12950362	566	42.48177929	604	47.54361606	668	42.22591678	576	37.77110465	520	0.973810952	0.042159789	normal	0.972480312	0.003830057	normal	0.940771299	-0.223724057	normal	0.864708978	-0.055082891	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ribonuclease P activity (GO:0004526);; Cellular Component: nucleus (GO:0005634);; Biological Process: tRNA processing (GO:0008033);; 	"K14527|3.77047e-86|ptr:463608|POP7; processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae); K14527 ribonuclease P/MRP protein subunit RPP20 [EC:3.1.26.5] (A)"	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	--	--	Rpp20 subunit of nuclear RNase MRP and P;; Alba	Ribonuclease P protein subunit p20 GN=POP7 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribonuclease P protein subunit p20 isoform X4 [Canis lupus familiaris] 
ENSG00000172339(ALG14)	--	5.004598	79	10.065671	108	6.009328	103	8.339104	132	7.40305	126	7.113025	88	0.408638704	0.699158821	normal	0.956073759	0.198391961	normal	0.957415982	-0.231676339	normal	0.636377246	0.232550419	normal	--	--	Biological Process: dolichol-linked oligosaccharide biosynthetic process (GO:0006488);; 	"K07441|1.68579e-129|hsa:199857|ALG14; ALG14, UDP-N-acetylglucosaminyltransferase subunit; K07441 beta-1,4-N-acetylglucosaminyltransferase [EC:2.4.1.141] (A)"	N-Glycan biosynthesis (ko00510)	[R]	General function prediction only	Oligosaccharide biosynthesis protein Alg14 like	UDP-N-acetylglucosamine transferase subunit ALG14 homolog GN=ALG14 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: UDP-N-acetylglucosamine transferase subunit ALG14 homolog isoform X1 [Ailuropoda melanoleuca]
ENSG00000172340(SUCLG2)	--	41.89646357	1564	40.75009473	1626	42.87883802	1597	45.6490265	1811	48.7604396	1783	47.93038411	1790	0.972410493	0.180548839	normal	0.981043513	0.111453875	normal	0.976522026	0.156164084	normal	0.461770153	0.148325515	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01900|0|hsa:8801|SUCLG2, GBETA; succinate-CoA ligase, GDP-forming, beta subunit (EC:6.2.1.4); K01900 succinyl-CoA synthetase beta subunit [EC:6.2.1.4 6.2.1.5] (A)"	Citrate cycle (TCA cycle) (ko00020);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)	[C]	Energy production and conversion	ATP-grasp domain;; CoA-ligase;; ATP-grasp domain	"Succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial (Precursor) GN=SUCLG2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial [Oryctolagus cuniculus]"
ENSG00000172345(STARD5)	--	0.6066613	55	0.541661	49	0.786141059	72	0.353494283	32	0.2696968	24	0.1561715	14	0.78947734	-0.783157958	normal	0.578438109	-1.005912926	normal	1.75E-06	-2.252375934	down	0.005086052	-1.353039156	down	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[I]	Lipid transport and metabolism	START domain	StAR-related lipid transfer protein 5 GN=STARD5 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: stAR-related lipid transfer protein 5 [Galeopterus variegatus]
ENSG00000172346(CSDC2)	--	1.76982	98	1.60002	90	1.66378	94	1.73532	96	2.2447	124	1.708814	86	0.970565293	-0.059634926	normal	0.873024483	0.434670791	normal	0.968039574	-0.134354906	normal	0.882495233	0.096531236	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[J]	"Translation, ribosomal structure and biogenesis"	'Cold-shock' DNA-binding domain	Cold shock domain-containing protein C2 GN=CSDC2 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: cold shock domain-containing protein C2 [Loxodonta africana] 
ENSG00000172348(RCAN2)	--	0.079273366	4	0.019162515	1	0.02628553	0	0.019816884	1	0.0255899	0	0.026094201	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: calcium-mediated signaling (GO:0019722);; 	K17903|1.20756e-168|pps:100968124|RCAN2; regulator of calcineurin 2; K17903 calcipressin-2 (A)	Thyroid hormone signaling pathway (ko04919)	[TR]	Signal transduction mechanisms;; General function prediction only	Calcipressin	Calcipressin-2 GN=RCAN2 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: calcipressin-2 isoform 1 [Dasypus novemcinctus] 
ENSG00000172349(IL16)	--	0	0	0.05630999	5	0	0	0.00482359	1	0.00467673	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PDZ domain (Also known as DHR or GLGF);; PDZ domain	Interleukin-16 GN=IL16 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: pro-interleukin-16 isoform X1 [Orycteropus afer afer]
ENSG00000172350(ABCG4)	--	0.574686602	27	0.515559983	13	0.257516082	18	0.163617522	11	0.401819379	27	0.116654724	8	0.807502939	-1.214788979	normal	0.915755712	0.954567085	normal	--	--	--	--	--	--	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Cellular Component: membrane (GO:0016020);; Molecular Function: ATPase activity (GO:0016887);; 	"K05680|0|ptr:466802|ABCG4; ATP-binding cassette, sub-family G (WHITE), member 4; K05680 ATP-binding cassette, subfamily G (WHITE), member 4 (A)"	ABC transporters (ko02010)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	ABC-2 type transporter;; ABC transporter;; AAA domain	ATP-binding cassette sub-family G member 4 GN=ABCG4 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: ATP-binding cassette sub-family G member 4 [Ceratotherium simum simum]
ENSG00000172354(GNB2)	--	144.1860843	3504	140.3958644	3446	135.658602	3477	156.230438	3640	163.1884279	3751	147.5332494	3624	0.991350616	0.024093047	normal	0.989267911	0.100883561	normal	0.990917692	0.051426536	normal	0.821676026	0.057968141	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K04537|0|tup:102484212|GNB2; guanine nucleotide binding protein (G protein), beta polypeptide 2; K04537 guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[R]	General function prediction only	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 GN=GNB2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 isoform 4 [Dasypus novemcinctus]
ENSG00000172361(CFAP53)	--	0.609721	19	0.244492	12	1.238696	24	0.376985	15	0.220618009	10	0.439345	16	--	--	--	--	--	--	0.977509846	-0.550512402	normal	--	--	--	--	--	--	--	--	--	--	"Tumour suppressor, Mitostatin"	Cilia- and flagella-associated protein 53 {ECO:0000312|HGNC:HGNC:26530} OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 11 [Ceratotherium simum simum]
ENSG00000172366(MCRIP2)	--	32.85095555	476	31.81449	433	32.0826	462	30.69229466	461	28.73481874	419	32.78152	395	0.968389064	-0.076775249	normal	0.967325169	-0.068599762	normal	0.934455722	-0.233504114	normal	0.66433168	-0.1263519	normal	--	--	--	--	--	--	--	FAM195 family	Protein FAM195A GN=FAM195A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM195A [Camelus bactrianus] 
ENSG00000172367(PDZD3)	--	0	0	0	0	0	0	0	0	0	0	0.021083299	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; Tricorn protease PDZ domain	Na(+)/H(+) exchange regulatory cofactor NHE-RF4 GN=PDZD3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF4 [Galeopterus variegatus]
ENSG00000172375(C2CD2L)	--	1.3459983	129	1.2293877	90	1.467159005	128	1.683641752	155	1.912710629	157	2.128600859	172	0.947908164	0.231546367	normal	0.157395046	0.771409984	normal	0.847808814	0.413741949	normal	0.191218076	0.459545746	normal	--	--	--	--	--	--	--	--	C2 domain-containing protein 2-like GN=C2CD2L OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: C2 domain-containing protein 2-like [Orcinus orca]
ENSG00000172379(ARNT2)	--	9.253479371	1274	9.855838235	1362	8.366599982	1152	7.645699424	1043	9.680523737	1320	8.483245284	1166	0.885979951	-0.3190323	normal	0.98097541	-0.066540278	normal	0.981264436	0.009123725	normal	0.572246299	-0.123200741	normal	[T]	Signal transduction mechanisms	"Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K15589|0|ptr:453583|ARNT2; aryl-hydrocarbon receptor nuclear translocator 2; K15589 aryl hydrocarbon receptor nuclear translocator 2 (A)	Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Renal cell carcinoma (ko05211)	[K]	Transcription	PAS domain;; PAS fold;; PAS fold;; Helix-loop-helix DNA-binding domain;; PAS domain	Aryl hydrocarbon receptor nuclear translocator 2 GN=ARNT2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: aryl hydrocarbon receptor nuclear translocator 2 [Oryctolagus cuniculus]
ENSG00000172380(GNG12)	--	71.31919	4227	70.72579	4173	76.09915	4425	86.69542	5194	72.79856	4313	77.5927	4622	0.970471023	0.266292198	normal	0.992165034	0.026170909	normal	0.992415879	0.054530127	normal	0.586683317	0.118178767	normal	--	--	--	"K04347|1.26579e-45|tup:102501535|GNG12; guanine nucleotide binding protein (G protein), gamma 12; K04347 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Regulation of actin cytoskeleton (ko04810);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Precursor) GN=GNG12 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 [Trichechus manatus latirostris] 
ENSG00000172382(PRSS27)	--	1.699091	60	0.730782535	33	1.677459	47	0.85262	30	1.561747	53	1.898635	62	0.419004477	-0.99411673	normal	0.896075348	0.638811448	normal	0.954241502	0.380622025	normal	0.985893701	0.03167565	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09628|0|hsa:83886|PRSS27, CAPH2, MPN; protease, serine 27; K09628 protease, serine 27 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Serine protease 27 (Precursor) GN=PRSS27 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine protease 27 [Orcinus orca]
ENSG00000172403(SYNPO2)	--	0.816776158	148	1.283694	245	0.830103309	150	1.518645222	284	1.348523169	244	2.143192909	411	0.002594418	0.902586686	normal	0.965741033	-0.027159175	normal	3.41E-10	1.436767424	up	0.116258856	0.769491069	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PDZ domain (Also known as DHR or GLGF);; Calcineurin-binding protein (Calsarcin)	Synaptopodin-2 GN=SYNPO2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: synaptopodin-2 [Galeopterus variegatus]
ENSG00000172404(DNAJB7)	--	0.418733	17	0.218739	9	0.342477	13	0.531979	22	0.2859	11	0.389502	16	0.986675758	0.315983346	normal	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09513|0|hsa:150353|DNAJB7, DJ5, HSC3; DnaJ (Hsp40) homolog, subfamily B, member 7; K09513 DnaJ homolog subfamily B member 7 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily B member 7 GN=DNAJB7 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 7 [Ceratotherium simum simum]
ENSG00000172409(CLP1)	--	11.21896005	338	11.34909717	371	10.159277	300	11.08529305	333	12.18016086	366	10.27837	340	0.967228703	-0.05209475	normal	0.967489848	-0.04083451	normal	0.952946945	0.171468399	normal	0.966060173	0.020878506	normal	[A]	RNA processing and modification	Biological Process: mRNA 3'-end processing (GO:0031124);; 	K14399|0|bacu:103006007|CLP1; cleavage and polyadenylation factor I subunit 1; K14399 polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78] (A)	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Pre-mRNA cleavage complex II protein Clp1;; Molybdopterin guanine dinucleotide synthesis protein B	Polyribonucleotide 5'-hydroxyl-kinase Clp1 {ECO:0000255|HAMAP-Rule:MF_03035} OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: polyribonucleotide 5'-hydroxyl-kinase Clp1 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000172421(EFCAB3)	--	0.194518197	5	0.196229696	5	0.31199944	7	0.154441289	4	0.1136271	2	0.116161309	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	EF-hand domain pair;; EF hand	EF-hand calcium-binding domain-containing protein 3 GN=EFCAB3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: EF-hand calcium-binding domain-containing protein 3 isoform 1 [Ceratotherium simum simum]
ENSG00000172426(RSPH9)	--	0.1941659	9	0.3792424	18	0.332764	15	0.1718665	8	0.3166064	14	0.321955123	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Radial spokehead-like protein	Radial spoke head protein 9 homolog GN=RSPH9 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: radial spoke head protein 9 homolog isoform X3 [Mustela putorius furo] 
ENSG00000172428(COPS9)	--	104.8362705	307	124.827	388	133.069577	425	100.693	330	98.1050204	286	97.9844774	300	0.965742492	0.073042493	normal	0.620011673	-0.459373837	normal	0.431060384	-0.508626455	normal	0.21269503	-0.311285323	normal	--	--	--	--	--	--	--	Myeloma-overexpressed-like	Myeloma-overexpressed gene 2 protein GN=MYEOV2 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: myeloma-overexpressed gene 2 protein homolog [Monodelphis domestica]
ENSG00000172432(GTPBP2)	--	10.39408725	611	8.182188318	486	10.28057632	581	9.557659129	577	9.67413779	554	11.75111614	615	0.967470733	-0.11314049	normal	0.9564306	0.16701608	normal	0.971311255	0.073570656	normal	0.913836245	0.036440749	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2	GTP-binding protein 2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: GTP-binding protein 2 [Loxodonta africana]
ENSG00000172456(FGGY)	--	2.170273	72	1.577021415	40	2.541634601	46	2.481568672	73	2.794751	91	2.3289442	63	0.974563851	-0.010705826	normal	0.031596583	1.135245401	normal	0.943722609	0.433210996	normal	0.323512648	0.501118359	normal	[C]	Energy production and conversion	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	--	--	[G]	Carbohydrate transport and metabolism	"FGGY family of carbohydrate kinases, C-terminal domain;; FGGY family of carbohydrate kinases, N-terminal domain"	FGGY carbohydrate kinase domain-containing protein GN=FGGY OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: FGGY carbohydrate kinase domain-containing protein [Myotis brandtii]
ENSG00000172458(IL17D)	--	4.140986735	84	3.234263474	59	3.094119	75	3.390242055	71	2.867992738	67	1.930386435	47	0.958406057	-0.268061934	normal	0.971043219	0.158212281	normal	0.782858624	-0.665421505	normal	0.669856706	-0.258954069	normal	--	--	Molecular Function: cytokine activity (GO:0005125);; Cellular Component: extracellular region (GO:0005576);; 	K05492|1.26562e-119|pps:100974554|IL17D; interleukin 17D; K05492 interleukin 17D (A)	--	--	--	Interleukin-17	Interleukin-17D (Precursor) GN=IL17D OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: interleukin-17D [Oryctolagus cuniculus]
ENSG00000172465(TCEAL1)	--	15.05563	275	15.600227	292	15.88459	296	21.0499	401	19.97138885	373	20.32608	377	0.440726499	0.510961954	normal	0.869198334	0.33026405	normal	0.858851889	0.339137074	normal	0.094247313	0.394124255	normal	--	--	--	--	--	--	--	Brain expressed X-linked like family	Transcription elongation factor A protein-like 1 GN=TCEAL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription elongation factor A protein-like 1 isoform X1 [Tupaia chinensis] 
ENSG00000172466(ZNF24)	--	13.3910743	1310	16.22213411	1587	12.6199342	1217	13.2482725	1314	13.1958321	1267	14.595262	1389	0.982387565	-0.026402881	normal	0.862172781	-0.345942342	normal	0.96773465	0.182213906	normal	0.776248753	-0.072790436	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:7572|ZNF24, KOX17, RSG-A, ZNF191, ZSCAN3, Zfp191; zinc finger protein 24; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 24 GN=ZNF24 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: uncharacterized protein LOC101282331 [Orcinus orca]
ENSG00000172469(MANEA)	--	5.508039	330	6.068462	329	5.121051747	303	3.861649	226	4.430128	262	5.48355	265	0.287536941	-0.573726485	normal	0.854714462	-0.348149727	normal	0.945985954	-0.200545723	normal	0.140764138	-0.374211439	normal	--	--	"Molecular Function: hydrolase activity, acting on glycosyl bonds (GO:0016798);; "	"K15538|0|hsa:79694|MANEA, ENDO, hEndo; mannosidase, endo-alpha (EC:3.2.1.130); K15538 glycoprotein endo-alpha-1,2-mannosidase [EC:3.2.1.130] (A)"	--	--	--	--	"Glycoprotein endo-alpha-1,2-mannosidase GN=MANEA OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: glycoprotein endo-alpha-1,2-mannosidase [Galeopterus variegatus]"
ENSG00000172476(RAB40A)	--	0.750603233	39	0.762788296	32	1.160623836	55	0.983947299	46	0.96563812	47	1.124521467	56	0.977727245	0.200064598	normal	0.946857081	0.513050897	normal	0.977492072	0.017234143	normal	0.771804782	0.222145169	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K07928|0|hsa:142684|RAB40A, RAR2, RAR2A; RAB40A, member RAS oncogene family; K07928 Ras-related protein Rab-40 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; SOCS box;; ADP-ribosylation factor family	Ras-related protein Rab-40A (Precursor) GN=RAB40A OS=Homo sapiens (Human) PE=2 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-40B isoform 1 [Trichechus manatus latirostris]
ENSG00000172493(AFF1)	--	7.193812225	1270	10.67261473	1497	8.250959724	1429	8.11241	1424	7.458442	1271	12.07761496	2100	0.976031645	0.134135085	normal	0.943425495	-0.257254341	normal	0.168513436	0.546611926	normal	0.72460536	0.172494688	normal	--	--	--	"K15184|0|hsa:4299|AFF1, AF4, MLLT2, PBM1; AF4/FMR2 family, member 1; K15184 AF4/FMR2 family member 1 (A)"	Transcriptional misregulation in cancer (ko05202)	--	--	AF-4 proto-oncoprotein	AF4/FMR2 family member 1 GN=AFF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: AF4/FMR2 family member 1 [Trichechus manatus latirostris]
ENSG00000172497(ACOT12)	--	0.3334715	3	0.0563638	2	0	0	0.1282108	2	0.14738106	0	0.291782015	2	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Molecular Function: lipid binding (GO:0008289);; 	"K01067|0|hsa:134526|ACOT12, CACH-1, Cach, STARD15, THEAL; acyl-CoA thioesterase 12 (EC:3.1.2.1); K01067 acetyl-CoA hydrolase [EC:3.1.2.1] (A)"	Pyruvate metabolism (ko00620)	[I]	Lipid transport and metabolism	Thioesterase superfamily;; START domain	Acyl-coenzyme A thioesterase 12 GN=ACOT12 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-coenzyme A thioesterase 12 [Orcinus orca]
ENSG00000172500(FIBP)	--	38.03293843	786	36.25159573	763	35.93228825	760	41.31435099	867	39.45413212	813	41.63970533	870	0.971962346	0.110464776	normal	0.974205429	0.070011298	normal	0.95865445	0.186377674	normal	0.60740737	0.12199535	normal	--	--	Molecular Function: fibroblast growth factor binding (GO:0017134);; 	--	--	--	--	Acidic fibroblast growth factor binding (FIBP)	Acidic fibroblast growth factor intracellular-binding protein GN=FIBP OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: acidic fibroblast growth factor intracellular-binding protein isoform X1 [Bubalus bubalis]
ENSG00000172508(CARNS1)	--	0.101659139	6	0.236673986	17	0.132832	6	0.072348689	5	0.248537748	15	0.028721961	2	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	--	"K14755|0|hsa:57571|CARNS1, ATPGD1; carnosine synthase 1 (EC:6.3.2.11); K14755 carnosine synthase [EC:6.3.2.11] (A)"	Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; beta-Alanine metabolism (ko00410)	--	--	ATP-grasp domain;; ATP-grasp domain	Carnosine synthase 1 GN=CARNS1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: carnosine synthase 1 [Camelus dromedarius]
ENSG00000172530(BANP)	--	4.2911181	174	6.564753916	280	8.924656352	334	6.778954928	274	3.836695432	149	6.486380165	258	0.234832273	0.619861092	normal	0.001874381	-0.924577981	normal	0.81358637	-0.378811349	normal	0.737434437	-0.231552908	normal	--	--	--	--	--	--	--	BEN domain	Protein BANP GN=BANP OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: protein BANP isoform X4 [Oryctolagus cuniculus]
ENSG00000172531(PPP1CA)	--	125.129649	3439	126.00972	3525	122.7083	3453	123.709014	3398	119.030811	3226	116.068735	3198	0.990734961	-0.048113901	normal	0.985729168	-0.149236422	normal	0.987945445	-0.118917704	normal	0.630477742	-0.106253453	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K06269|0|hsa:5499|PPP1CA, PP-1A, PP1A, PP1alpha, PPP1A; protein phosphatase 1, catalytic subunit, alpha isozyme (EC:3.1.3.16); K06269 serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] (A)"	mRNA surveillance pathway (ko03015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Long-term potentiation (ko04720);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Oxytocin signaling pathway (ko04921);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Herpes simplex infection (ko05168);; Proteoglycans in cancer (ko05205)	[TR]	Signal transduction mechanisms;; General function prediction only	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase PP1-alpha catalytic subunit GN=PPP1CA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase PP1-alpha catalytic subunit isoform X1 [Eptesicus fuscus]
ENSG00000172534(HCFC1)	--	18.43687111	3251	21.6947559	3772	18.82014135	3503	18.01470348	3159	22.75934496	3888	23.37480587	4279	0.989679209	-0.072213258	normal	0.991554676	0.022263194	normal	0.96060564	0.280281596	normal	0.770700335	0.085389506	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K14966|0|ptr:465933|HCFC1; host cell factor C1; K14966 host cell factor (A)	Herpes simplex infection (ko05168)	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	"Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Fibronectin type III domain"	HCF C-terminal chain 6 GN=HCFC1 OS=Homo sapiens (Human) PE=1 SV=2	DK	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	PREDICTED: host cell factor 1 isoform X3 [Oryctolagus cuniculus]
ENSG00000172543(CTSW)	--	0	0	0.045540535	1	0	0	0	0	0.0391616	0	0.0397201	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K08569|0|hsa:1521|CTSW, LYPN; cathepsin W; K08569 cathepsin W [EC:3.4.22.-] (A)"	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin propeptide inhibitor domain (I29)	Cathepsin W (Precursor) GN=CTSW OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin W [Orcinus orca]
ENSG00000172548(NIPAL4)	--	6.076651886	350	5.962386	346	4.831504262	282	17.12228471	1014	18.24264077	1063	13.1977929	788	9.99E-15	1.499754189	up	2.22E-16	1.593691983	up	2.43E-13	1.469289065	up	7.37E-13	1.528445703	up	--	--	Molecular Function: magnesium ion transmembrane transporter activity (GO:0015095);; Biological Process: magnesium ion transport (GO:0015693);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Magnesium transporter NIPA;; Multidrug resistance efflux transporter;; EamA-like transporter family	Magnesium transporter NIPA4 GN=NIPAL4 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: magnesium transporter NIPA4 [Chrysochloris asiatica]
ENSG00000172568(FNDC9)	--	0.027226	1	0.205768	2	0	0	0	0	0.0530044	1	0.117998	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Fibronectin type III domain-containing protein 9 GN=FNDC9 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: fibronectin type III domain-containing protein 9 [Equus caballus] 
ENSG00000172572(PDE3A)	--	0.070197095	9	0.1898696	23	0.102537	12	0.38901499	50	0.634536	78	0.768673751	99	0.0002098	2.262078016	up	0.000325131	1.677110877	up	5.21E-12	2.887262936	up	0.000103647	2.347244365	up	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13296|0|hsa:5139|PDE3A, CGI-PDE, CGI-PDE_A, CGI-PDE-A; phosphodiesterase 3A, cGMP-inhibited (EC:3.1.4.17); K19021 cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:3.1.4.17] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Insulin signaling pathway (ko04910);; Progesterone-mediated oocyte maturation (ko04914);; Morphine addiction (ko05032)	--	--	3'5'-cyclic nucleotide phosphodiesterase	"cGMP-inhibited 3',5'-cyclic phosphodiesterase A GN=PDE3A OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: cGMP-inhibited 3',5'-cyclic phosphodiesterase A [Ceratotherium simum simum]"
ENSG00000172575(RASGRP1)	--	0.3552386	30	0.577118192	42	0.938776388	30	1.410218532	122	2.722238318	226	1.292492284	113	4.96E-08	1.939954294	up	1.11E-16	2.365466662	up	4.56E-07	1.853478261	up	0.002642416	2.154795636	up	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	K04350|0|mcf:102124752|RASGRP1; RAS guanyl releasing protein 1 (calcium and DAG-regulated); K04350 RAS guanyl-releasing protein 1 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Platelet activation (ko04611);; T cell receptor signaling pathway (ko04660);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	RasGEF domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; RasGEF N-terminal motif;; EF-hand domain pair;; EF-hand domain;; EF hand	RAS guanyl-releasing protein 1 GN=RASGRP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: RAS guanyl-releasing protein 1 isoform X1 [Lipotes vexillifer]
ENSG00000172586(CHCHD1)	--	29.86817	349	32.75769	391	33.57063	396	41.66744	504	39.13286	456	37.0621	433	0.435255507	0.49753277	normal	0.94597707	0.199722801	normal	0.963063466	0.120136277	normal	0.246983024	0.272666765	normal	--	--	--	--	--	[S]	Function unknown	CHCH domain	Coiled-coil-helix-coiled-coil-helix domain-containing protein 1 GN=CHCHD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil-helix-coiled-coil-helix domain-containing protein 1 [Galeopterus variegatus]
ENSG00000172590(MRPL52)	--	46.44938561	380	41.37290953	383	64.57238769	451	80.30644503	447	53.01384978	425	44.44272495	350	0.945517632	0.202686945	normal	0.960855285	0.128211165	normal	0.801986993	-0.372641597	normal	0.983562217	-0.012098284	normal	--	--	--	K17433|2.31457e-71|hsa:122704|MRPL52; mitochondrial ribosomal protein L52; K17433 large subunit ribosomal protein L52 (A)	--	--	--	--	"39S ribosomal protein L52, mitochondrial (Precursor) GN=MRPL52 OS=Homo sapiens (Human) PE=2 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L52, mitochondrial isoform X1 [Panthera tigris altaica]"
ENSG00000172594(SMPDL3A)	--	2.402686	69	1.9931381	57	2.463421734	70	1.630333	47	1.611116	46	3.003832	87	0.883419737	-0.569308616	normal	0.962867913	-0.321247631	normal	0.952589347	0.299553652	normal	0.843804337	-0.141949382	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	"K01128|0|pps:100981031|SMPDL3A; sphingomyelin phosphodiesterase, acid-like 3A; K01128 [EC:3.1.4.-] (A)"	--	[I]	Lipid transport and metabolism	Calcineurin-like phosphoesterase	Acid sphingomyelinase-like phosphodiesterase 3a (Precursor) GN=SMPDL3A OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: acid sphingomyelinase-like phosphodiesterase 3a isoform X1 [Lipotes vexillifer]
ENSG00000172602(RND1)	--	0.611304146	15	0.643765321	22	0.746033	23	9.4955316	322	14.5356173	486	8.294490624	281	0	4.260878308	up	0	4.353247512	up	0	3.518723072	up	3.47E-12	4.160950159	up	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07531|1.33023e-169|ptr:466975|RND1; Rho family GTPase 1; K07531 Rho family GTPase 1 (A)	Axon guidance (ko04360)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein Rho6 (Precursor) GN=RND1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	rho-related GTP-binding protein Rho6 precursor [Bos taurus] 
ENSG00000172613(RAD9A)	--	8.452079	280	8.220874	283	6.91493643	289	10.266813	319	9.671821	320	9.072319	338	0.955653425	0.156492448	normal	0.954938924	0.15506369	normal	0.940828766	0.216613208	normal	0.57255009	0.176530873	normal	--	--	Biological Process: DNA damage checkpoint (GO:0000077);; Cellular Component: checkpoint clamp complex (GO:0030896);; 	K10994|0|pps:100984970|RAD9A; RAD9 homolog A (S. pombe); K10994 cell cycle checkpoint control protein RAD9A [EC:3.1.11.2] (A)	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Rad9	Cell cycle checkpoint control protein RAD9A GN=RAD9A OS=Homo sapiens (Human) PE=1 SV=1	DL	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	PREDICTED: cell cycle checkpoint control protein RAD9A isoform X2 [Tupaia chinensis] 
ENSG00000172638(EFEMP2)	--	1.35892161	47	0.771201381	28	1.098163281	36	0.957012085	34	0.357913409	12	1.127116818	35	0.954240471	-0.479446521	normal	0.820245953	-1.146722645	normal	0.982775636	-0.046933784	normal	0.512884238	-0.476016818	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; Complement Clr-like EGF-like;; Coagulation Factor Xa inhibitory site;; EGF domain;; EGF-like domain	EGF-containing fibulin-like extracellular matrix protein 2 (Precursor) GN=EFEMP2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: EGF-containing fibulin-like extracellular matrix protein 2 [Equus przewalskii]
ENSG00000172640(OR10AD1)	--	0.0603714	1	0	0	0.0603506	0	0	0	0.0588992	0	0.119342	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:121275|OR10AD1, OR10AD1P, OR12-1; olfactory receptor, family 10, subfamily AD, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 10AD1 GN=OR10AD1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 10AD1 [Felis catus]
ENSG00000172650(AGAP5)	--	3.568765087	432	3.075892227	357	3.231488114	367	2.918728096	404	3.417422865	393	4.191355844	458	0.962070312	-0.127040921	normal	0.961794528	0.116707367	normal	0.883809958	0.310129929	normal	0.762096755	0.0976237	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; PH domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Pleckstrin homology domain;; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 GN=AGAP5 OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X2 [Eptesicus fuscus]"
ENSG00000172661(WASHC2C)	--	9.10156998	1002	12.21193356	1336	10.53714651	1148	10.2913854	1126	10.214279	1122	14.36049705	1572	0.972219252	0.137293394	normal	0.931083277	-0.272936267	normal	0.573394321	0.444684553	normal	0.797742141	0.111704006	normal	--	--	--	"K18462|0|hsa:387680|FAM21A, FAM21B, bA56A21.1, bA98I6.1; family with sequence similarity 21, member A; K18462 WASH complex subunit FAM21 (A)"	--	--	--	"WASH complex subunit CAP-Z interacting, central region"	WASH complex subunit FAM21A GN=FAM21A OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: WASH complex subunit FAM21A-like [Equus caballus]
ENSG00000172663(TMEM134)	--	12.6067282	269	7.517615686	193	11.203122	258	8.9705863	212	10.691765	254	9.019163	224	0.840739649	-0.371974381	normal	0.847059538	0.372251515	normal	0.944189795	-0.210836287	normal	0.845186733	-0.082079993	normal	--	--	--	--	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF872)	Transmembrane protein 134 GN=TMEM134 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 134 isoform X1 [Chrysochloris asiatica]
ENSG00000172667(ZMAT3)	--	6.156884174	680	6.453497201	698	5.796745325	671	8.232837612	878	8.656020651	1039	9.438685291	1001	0.850152147	0.337181956	normal	0.182512952	0.551484869	normal	0.127827982	0.56771152	normal	0.002552363	0.489259873	normal	--	--	--	"K10137|0|hsa:64393|ZMAT3, PAG608, WIG-1, WIG1; zinc finger, matrin-type 3; K10137 zinc finger, matrin type 3 (A)"	p53 signaling pathway (ko04115)	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; U1 zinc finger	Zinc finger matrin-type protein 3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger matrin-type protein 3 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000172671(ZFAND4)	--	2.658910361	135	2.076423416	113	2.407387106	109	2.6803676	135	1.8490129	95	1.515224102	78	0.96827007	-0.030485313	normal	0.946810135	-0.267835082	normal	0.857102524	-0.483112913	normal	0.627433034	-0.236118285	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	"K12163|0|hsa:93550|ZFAND4, ANUBL1; zinc finger, AN1-type domain 4; K12163 AN1-type zinc finger and ubiquitin domain-containing protein 1 (A)"	--	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; AN1-like Zinc finger;; Ubiquitin-2 like Rad60 SUMO-like	AN1-type zinc finger protein 4 GN=ZFAND4 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: AN1-type zinc finger protein 4 [Leptonychotes weddellii]
ENSG00000172687(ZNF738)	--	1.109734271	24	0.553655549	14	1.764994482	29	1.549570661	39	1.353683274	29	1.857061	38	0.943364075	0.63734089	normal	0.900273077	0.956127889	normal	0.973910314	0.364983728	normal	0.340499156	0.641321961	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	KRAB box	Protein ZNF738 GN=ZNF738 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 92-like [Myotis davidii]
ENSG00000172716(SLFN11)	--	14.81462099	878	16.18860812	852	19.73799787	958	11.50891594	683	11.07982098	616	12.62671314	623	0.736744537	-0.392386723	normal	0.415779601	-0.488325417	normal	0.04152771	-0.627846192	normal	0.002089528	-0.505232451	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	Divergent AAA domain;; Uncharacterized conserved protein (DUF2075)	Schlafen family member 11 GN=SLFN11 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: schlafen family member 11 isoform X1 [Equus caballus] 
ENSG00000172725(CORO1B)	--	41.20736318	1457	54.0547604	1610	38.91733921	1262	45.28572597	1468	48.48626708	1607	59.06773157	2021	0.983657561	-0.019960204	normal	0.98422037	-0.024094664	normal	0.011092413	0.670425392	normal	0.479303151	0.214742107	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K13886|0|hsa:57175|CORO1B, CORONIN-2; coronin, actin binding protein, 1B; K13886 coronin-1B/1C/6 (A)"	--	[Z]	Cytoskeleton	"Domain of unknown function (DUF1900);; Domain of unknown function (DUF1899);; WD domain, G-beta repeat"	Coronin-1B GN=CORO1B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: coronin-1B [Pteropus alecto] 
ENSG00000172728(FUT10)	--	3.799818507	388	3.734923487	380	3.961772764	363	4.253182712	487	4.50451096	454	4.041607874	466	0.895489424	0.295984877	normal	0.933284361	0.234411922	normal	0.835474321	0.350776003	normal	0.203824662	0.2935829	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: fucosyltransferase activity (GO:0008417);; Cellular Component: membrane (GO:0016020);; 	"K09669|0|hsa:84750|FUT10; fucosyltransferase 10 (alpha (1,3) fucosyltransferase) (EC:2.4.1.69); K09669 alpha-1,3-fucosyltransferase 10 [EC:2.4.1.-] (A)"	--	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Glycosyltransferase family 10 (fucosyltransferase)	"Alpha-(1,3)-fucosyltransferase 10 GN=FUT10 OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-(1,3)-fucosyltransferase 10 isoform X1 [Equus przewalskii]"
ENSG00000172731(LRRC20)	--	18.27531159	1006	20.11076984	1006	22.29883197	1200	14.89827729	772	14.03944118	642	11.5529899	576	0.679491321	-0.412068975	normal	0.019758001	-0.668143131	normal	1.12E-07	-1.065203222	down	6.80E-06	-0.712490872	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 20 GN=LRRC20 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 20 [Elephantulus edwardii]
ENSG00000172732(MUS81)	--	13.15130788	543	12.79492065	553	13.49062374	577	16.80334332	703	13.075196	537	14.17568365	556	0.842477762	0.34089056	normal	0.97016645	-0.063607421	normal	0.971455331	-0.061613359	normal	0.782360903	0.080427231	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: nuclease activity (GO:0004518);; 	"K08991|0|hsa:80198|MUS81, SLX3; MUS81 structure-specific endonuclease subunit (EC:3.1.22.-); K08991 crossover junction endonuclease MUS81 [EC:3.1.22.-] (A)"	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	ERCC4 domain	Crossover junction endonuclease MUS81 GN=MUS81 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: crossover junction endonuclease MUS81 [Ceratotherium simum simum]
ENSG00000172733(PURG)	--	0.506216047	11	0.265999339	13	0.367587633	17	0	0	0.040169673	1	0.061530408	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	PurA ssDNA and RNA-binding protein;; Protein of unknown function (DUF3276)	Purine-rich element-binding protein gamma GN=PURG OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: purine-rich element-binding protein gamma isoform X1 [Mustela putorius furo]
ENSG00000172738(TMEM217)	--	0.0424434	1	0.087108965	2	0.386584079	8	0.170980589	4	0.083555684	1	0.127613453	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF4534)	Transmembrane protein 217 GN=TMEM217 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 217-like [Physeter catodon]
ENSG00000172748(ZNF596)	--	0.488659	25	1.6720137	17	0.562858	17	1.693749	28	0.848878	14	0.385356493	20	0.985859269	0.125383164	normal	--	--	--	0.988395162	0.209016428	normal	0.985148518	0.048665798	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:169270|ZNF596; zinc finger protein 596 (EC:2.1.1.43); K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; C2H2-type zinc finger;; BolA-like protein;; Protein of unknown function (DUF3936);; GAGA factor"	Zinc finger protein 596 GN=ZNF596 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 596 isoform X1 [Galeopterus variegatus] 
ENSG00000172752(COL6A5)	--	0	0	0	0	0	0	0.010507304	2	0.017377318	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06238|0|hsa:256076|COL6A5, COL29A1, VWA4; collagen, type VI, alpha 5; K06238 collagen, type VI, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974)	[W]	Extracellular structures	von Willebrand factor type A domain;; von Willebrand factor type A domain;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; vWA found in TerF C terminus;; VWA domain containing CoxE-like protein;; Radical SAM superfamily;; Copine	Collagen alpha-5(VI) chain (Precursor) GN=COL6A5 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: collagen alpha-5(VI) chain [Pteropus alecto]
ENSG00000172757(CFL1)	--	690.7097806	15810	719.590473	16667	716.4524894	16627	888.325276	20224	837.322415	18779	714.772433	16182	0.978778338	0.324370808	normal	0.996116021	0.150686348	normal	0.997390251	-0.04742503	normal	0.538605332	0.146626579	normal	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	K05765|7.62047e-115|umr:103679469|CFL1; cofilin 1 (non-muscle); K05765 cofilin (A)	Axon guidance (ko04360);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Pertussis (ko05133)	[Z]	Cytoskeleton	Cofilin/tropomyosin-type actin-binding protein	Cofilin-1 GN=CFL1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	Cofilin-1 [Pteropus alecto]
ENSG00000172765(TMCC1)	--	4.364772822	451	4.554849855	488	4.77459748	500	9.947378197	842	11.27384203	891	10.74258088	993	0.000148992	0.867664522	normal	0.000320622	0.845151645	normal	3.54E-06	0.979431509	normal	7.18E-09	0.901125169	normal	--	--	--	--	--	[S]	Function unknown	Predicted transmembrane and coiled-coil 2 protein	Transmembrane and coiled-coil domains protein 1 GN=TMCC1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transmembrane and coiled-coil domains protein 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000172766(NAA16)	--	4.362485013	302	4.6209019	336	4.79535724	350	3.794659962	270	5.288711888	375	3.580954214	243	0.948218131	-0.191390886	normal	0.958726334	0.136421395	normal	0.405206079	-0.531916118	normal	0.613861308	-0.175068608	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K00670|0|pps:100981235|NAA16; N(alpha)-acetyltransferase 16, NatA auxiliary subunit; K00670 peptide alpha-N-acetyltransferase [EC:2.3.1.88] (A)"	--	[B]	Chromatin structure and dynamics	"NMDA receptor-regulated protein 1;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	"N-alpha-acetyltransferase 16, NatA auxiliary subunit GN=NAA16 OS=Homo sapiens (Human) PE=1 SV=2"	B	Chromatin structure and dynamics	"PREDICTED: N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 1 [Ceratotherium simum simum]"
ENSG00000172771(EFCAB12)	--	0.3104733	14	0.222083022	10	0.31850054	11	0.266908709	12	0.238057207	9	0.373623353	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	--	EF-hand calcium-binding domain-containing protein 12 GN=EFCAB12 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: EF-hand calcium-binding domain-containing protein 12 [Pteropus alecto]
ENSG00000172775(FAM192A)	--	52.38238048	1547	49.1730668	1610	49.964988	1612	50.58654051	1732	56.2843266	1788	54.97921979	1675	0.978972447	0.132009522	normal	0.979375039	0.12974381	normal	0.984357691	0.046974676	normal	0.644620054	0.102205501	normal	--	--	--	--	--	[S]	Function unknown	N-terminal domain of NEFA-interacting nuclear protein NIP30	Protein FAM192A GN=FAM192A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM192A [Ceratotherium simum simum]
ENSG00000172780(RAB43)	--	16.88542247	1169	16.97240725	1137	16.67752201	1044	19.05487167	1218	19.72524567	1260	17.36276727	1013	0.981287825	0.02837041	normal	0.974922231	0.126604912	normal	0.978948395	-0.051702944	normal	0.894182217	0.03764947	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07930|8.59085e-146|ptr:100615763|RAB43; RAB43, member RAS oncogene family; K07930 Ras-related protein Rab-43 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-43 GN=RAB43 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-43 [Ochotona princeps]
ENSG00000172785(CBWD1)	--	9.071340532	292	9.814721302	334	10.36056646	337	10.25644581	347	10.64611966	347	9.858914576	343	0.940442384	0.217086242	normal	0.967149743	0.033512136	normal	0.968472454	0.017092514	normal	0.81295575	0.085697488	normal	[R]	General function prediction only	--	--	--	[H]	Coenzyme transport and metabolism	"CobW/HypB/UreG, nucleotide-binding domain;; Cobalamin synthesis protein cobW C-terminal domain"	COBW domain-containing protein 1 GN=CBWD1 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: COBW domain-containing protein 2 isoform X1 [Equus przewalskii]
ENSG00000172789(HOXC5)	--	2.251976	77	1.959508	68	2.915821147	71	2.0426485	66	2.646124	87	2.646650001	89	0.963247196	-0.247875927	normal	0.94562359	0.327599274	normal	0.949516567	0.311752455	normal	0.830638678	0.143709636	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09305|3.77361e-134|ptg:102962924|HOXC5; homeobox C5; K09305 homeobox protein HoxA/B/C5 (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-C5 GN=HOXC5 OS=Homo sapiens (Human) PE=3 SV=1	K	Transcription	PREDICTED: homeobox protein Hox-C5 [Panthera tigris altaica]
ENSG00000172794(RAB37)	--	0.322132464	15	0.117378803	6	0.14954117	4	0.461017002	22	2.00148476	86	0.755893367	37	0.983245498	0.480853171	normal	3.56E-13	3.523077763	up	0.000216395	2.797604689	up	0.091868574	2.515228835	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07914|4.02983e-141|ggo:101144199|RAB37; ras-related protein Rab-37 isoform 1; K07914 Ras-related protein Rab-37 (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-37 (Precursor) GN=RAB37 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-37 isoform X1 [Orycteropus afer afer]
ENSG00000172795(DCP2)	--	3.873562467	485	3.820386	469	3.999353213	490	4.05072928	510	4.536641878	561	4.7029921	587	0.970911947	0.04155187	normal	0.933945536	0.236288887	normal	0.927051494	0.25157702	normal	0.474388582	0.178680908	normal	[LR]	"Replication, recombination and repair;; General function prediction only"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: manganese ion binding (GO:0030145);; 	K12613|0|ptr:462001|DCP2; decapping mRNA 2; K12613 mRNA-decapping enzyme subunit 2 [EC:3.6.1.62] (A)	RNA degradation (ko03018)	[A]	RNA processing and modification	"Dcp2, box A domain;; NUDIX domain"	m7GpppN-mRNA hydrolase GN=DCP2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: m7GpppN-mRNA hydrolase isoform 1 [Ceratotherium simum simum]
ENSG00000172809(RPL38)	--	754.2690987	3502	854.487304	3705	731.4392057	3847	999.5476069	4607	828.2448069	3649	684.7418043	3444	0.890893208	0.364676389	normal	0.991046748	-0.043381107	normal	0.98502159	-0.167870344	normal	0.82765297	0.05990261	normal	--	--	--	K02923|1.27743e-25|ocu:100352574|60S ribosomal protein L38; K02923 large subunit ribosomal protein L38e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L38e protein family	60S ribosomal protein L38 GN=RPL38 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L38 [Oryctolagus cuniculus]
ENSG00000172817(CYP7B1)	--	0.183353082	10	0.4091776	21	0.1817677	7	0.635729241	35	0.442585	21	0.545447246	30	0.171657993	1.635005001	normal	0.987648728	-0.019987229	normal	0.122100887	1.880939776	normal	0.073873163	1.155037357	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07430|0|hsa:9420|CYP7B1, CBAS3, CP7B, SPG5A; cytochrome P450, family 7, subfamily B, polypeptide 1 (EC:1.14.13.100); K07430 oxysterol 7-alpha-hydroxylase [EC:1.14.13.100] (A)"	Primary bile acid biosynthesis (ko00120);; Steroid hormone biosynthesis (ko00140)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	25-hydroxycholesterol 7-alpha-hydroxylase GN=CYP7B1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: 25-hydroxycholesterol 7-alpha-hydroxylase-like isoform X1 [Mustela putorius furo] 
ENSG00000172818(OVOL1)	--	0.01789327	1	0.05902702	2	0	0	0	0	0.028898705	0	0.017693478	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09216|0|hsa:5017|OVOL1, HOVO1; ovo-like zinc finger 1; K09216 ovo (A)"	--	[K]	Transcription	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Putative transcription factor Ovo-like 1 GN=OVOL1 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: putative transcription factor Ovo-like 1 isoform X1 [Tupaia chinensis] 
ENSG00000172819(RARG)	--	15.57326295	833	12.82709965	738	13.56657662	726	11.0351224	492	11.16250544	539	10.81220091	449	0.001137863	-0.78857428	normal	0.484052288	-0.473621378	normal	0.012122722	-0.699674066	normal	8.04E-05	-0.655648508	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08529|0|mcf:102142840|RARG; retinoic acid receptor, gamma; K08529 retinoic acid receptor gamma (A)"	--	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Retinoic acid receptor gamma GN=RARG OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"Retinoic acid receptor gamma, partial [Bos mutus]"
ENSG00000172824(CES4A)	--	0.41497234	17	0.807555446	32	0.483415437	21	0.642178697	26	0.861334229	31	0.815342309	31	0.976622199	0.542282836	normal	0.983149093	-0.064149905	normal	0.970430642	0.522452285	normal	0.72414429	0.309123857	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	Carboxylesterase 4A (Precursor) GN=CES4A OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: carboxylesterase 4A isoform X1 [Tupaia chinensis]
ENSG00000172828(CES3)	--	1.823341227	131	1.623758986	129	1.376927149	103	1.329062	103	1.684542851	126	2.889561424	211	0.906081636	-0.372810005	normal	0.966672615	-0.054724728	normal	0.001340705	1.015671732	up	0.719950803	0.258096786	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	K15743|0|ggo:101143341|CES3; LOW QUALITY PROTEIN: carboxylesterase 3; K15743 carboxylesterase 3/5 [EC:3.1.1.1] (A)	--	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	Carboxylesterase 3 (Precursor) GN=CES3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	carboxylesterase 3 precursor [Sus scrofa]
ENSG00000172830(SSH3)	--	11.09248017	698	9.27027536	576	11.1633642	697	9.355271185	598	12.67763574	775	8.675731267	537	0.92795878	-0.253310652	normal	0.712245256	0.40577947	normal	0.762456695	-0.383577054	normal	0.867165512	-0.066467836	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K05766|0|hsa:54961|SSH3, SSH3L; slingshot protein phosphatase 3 (EC:3.1.3.16 3.1.3.48); K05766 protein phosphatase slingshot [EC:3.1.3.16 3.1.3.48] (A)"	Regulation of actin cytoskeleton (ko04810)	--	--	"Dual specificity phosphatase, catalytic domain;; DEK C terminal domain"	Protein phosphatase Slingshot homolog 3 GN=SSH3 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: protein phosphatase Slingshot homolog 3 [Eptesicus fuscus]
ENSG00000172831(CES2)	--	14.67119096	1163	13.451792	1071	14.04842146	1138	18.44929715	1482	19.4271748	1509	18.04212769	1369	0.891680452	0.318488611	normal	0.47417924	0.472643016	normal	0.939846467	0.258017416	normal	0.03024257	0.349380651	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K03927|0|hsa:8824|CES2, CE-2, CES2A1, PCE-2, iCE; carboxylesterase 2 (EC:3.1.1.1 3.1.1.84 3.1.1.56); K03927 carboxylesterase 2 [EC:3.1.1.1 3.1.1.84 3.1.1.56] (A)"	Drug metabolism - other enzymes (ko00983)	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold;; Prolyl oligopeptidase family	Cocaine esterase (Precursor) GN=CES2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cocaine esterase [Equus caballus]
ENSG00000172840(PDP2)	--	7.024385888	638	7.275178298	719	6.173033245	729	4.731811	461	5.74290657	494	7.043730459	692	0.387393798	-0.49820352	normal	0.181523077	-0.561473575	normal	0.972645796	-0.083260915	normal	0.158361145	-0.360767283	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K01102|0|hsa:57546|PDP2, PPM2C2; pyruvate dehyrogenase phosphatase catalytic subunit 2 (EC:3.1.3.43); K01102 pyruvate dehydrogenase phosphatase [EC:3.1.3.43] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C	"[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial (Precursor) GN=PDP2 OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial isoform X1 [Tupaia chinensis] "
ENSG00000172845(SP3)	--	29.85079007	1969	29.601334	2029	27.10299029	1789	20.03360062	1366	21.73931776	1405	20.27831334	1355	0.135034998	-0.557812063	normal	0.173952654	-0.551128661	normal	0.715009276	-0.408753622	normal	0.000465142	-0.509466066	normal	[R]	General function prediction only	--	K09193|0|ptr:459750|SP3; Sp3 transcription factor; K09193 transcription factor Sp3 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Transcription factor Sp3 GN=SP3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor Sp3 [Orcinus orca]
ENSG00000172869(DMXL1)	--	5.224743461	975	5.643154166	878	5.363202741	952	5.401323638	1009	5.413376567	952	6.036980994	1099	0.979325494	0.018590989	normal	0.974320415	0.09515665	normal	0.959322391	0.198572648	normal	0.658795579	0.104636715	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"RAVE protein 1 C terminal;; WD domain, G-beta repeat"	DmX-like protein 1 GN=DMXL1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: Dmx-like 1 isoform X2 [Equus caballus] 
ENSG00000172878(METAP1D)	--	5.265118982	219	4.060055088	190	3.707598457	168	2.472615847	108	2.53471647	111	3.11488	141	0.000631438	-1.040114535	down	0.070669872	-0.788552348	normal	0.93860482	-0.258514002	normal	0.017743836	-0.701282859	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K01265|0|ptr:100609894|METAP1D; methionyl aminopeptidase type 1D (mitochondrial); K01265 methionyl aminopeptidase [EC:3.4.11.18] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Metallopeptidase family M24	"Methionine aminopeptidase 1D, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03174} (Precursor) GN=METAP1D OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: LOW QUALITY PROTEIN: methionine aminopeptidase 1D, mitochondrial [Orcinus orca]"
ENSG00000172888(ZNF621)	--	7.132736182	786	7.50397495	817	7.833226804	777	6.272743985	680	6.889646225	748	6.876983057	732	0.937376793	-0.239323307	normal	0.965591577	-0.148437093	normal	0.972492332	-0.094173518	normal	0.474597818	-0.16092861	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:285268|ZNF621; zinc finger protein 621; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 621 GN=ZNF621 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 629-like [Ceratotherium simum simum]
ENSG00000172889(EGFL7)	--	49.77362611	899	49.18348052	802	56.17837	856	47.26479136	753	55.25330031	880	39.81713229	638	0.909646042	-0.285968637	normal	0.971546874	0.112272577	normal	0.617762116	-0.431459592	normal	0.357070764	-0.192616509	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	EMI domain;; Calcium-binding EGF domain;; EGF-like domain	Epidermal growth factor-like protein 7 (Precursor) GN=EGFL7 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neurogenic locus notch homolog protein 4 isoform X7 [Equus caballus]
ENSG00000172890(NADSYN1)-2	--	25.589722	1388	24.97120774	1325	28.38435094	1594	27.28852978	1516	25.7859607	1363	27.92247862	1483	0.980561606	0.096327877	normal	0.982350544	0.019344876	normal	0.980087972	-0.112313974	normal	0.996314771	-0.002688904	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000172890(NADSYN1)-3	--	2.15836	61	2.15828	61	1.61236	45	1.9032	54	2.05967	58	1.56846	45	0.972037698	-0.201289316	normal	0.974368011	-0.091847377	normal	0.980094014	-0.008021857	normal	0.895946735	-0.111227105	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000172893(DHCR7)	--	131.0854616	5265	131.2842713	5344	141.9351842	5825	54.9381992	2119	57.03715073	2202	133.5005453	5246	2.85E-14	-1.343241785	down	7.25E-13	-1.299939447	down	0.989698569	-0.159288085	normal	0.088810939	-0.798800295	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K00213|0|hsa:1717|DHCR7, SLOS; 7-dehydrocholesterol reductase (EC:1.3.1.21); K00213 7-dehydrocholesterol reductase [EC:1.3.1.21] (A)"	Steroid biosynthesis (ko00100)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Ergosterol biosynthesis ERG4/ERG24 family	7-dehydrocholesterol reductase GN=DHCR7 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: 7-dehydrocholesterol reductase [Camelus ferus]
ENSG00000172901(LVRN)	--	0.13427544	2	0.200450992	5	0	0	0.078032224	2	0.076599902	1	0.392001739	10	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	"K13724|0|hsa:206338|AQPEP, APQ, LVRN; laeverin; K13724 aminopeptidase Q [EC:3.4.11.-] (A)"	--	[EO]	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Peptidase family M1;; ERAP1-like C-terminal domain;; Peptidase MA superfamily	Aminopeptidase Q GN=AQPEP OS=Homo sapiens (Human) PE=1 SV=4	EO	"Amino acid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: aminopeptidase Q-like [Balaenoptera acutorostrata scammoni]
ENSG00000172915(NBEA)	--	3.37871938	650	4.53382107	737	3.706302612	654	3.276546288	639	5.325107026	762	3.90554926	722	0.973131783	-0.055324153	normal	0.975355912	0.026646049	normal	0.966639425	0.134121482	normal	0.910560202	0.035928513	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; Domain of Unknown Function (DUF1088);; PH domain associated with Beige/BEACH;; Concanavalin A-like lectin/glucanases superfamily;; WD domain, G-beta repeat"	Neurobeachin GN=NBEA OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: neurobeachin isoform X1 [Mustela putorius furo]
ENSG00000172922(RNASEH2C)	--	23.26238106	590	20.77124	618	19.87354781	580	21.1673501	511	18.27067	483	17.95437025	523	0.934149716	-0.23755846	normal	0.786488254	-0.37596661	normal	0.959902755	-0.157101813	normal	0.231231648	-0.258353097	normal	--	--	Biological Process: RNA catabolic process (GO:0006401);; Cellular Component: ribonuclease H2 complex (GO:0032299);; 	"K10745|6.15803e-108|hsa:84153|RNASEH2C, AGS3, AYP1; ribonuclease H2, subunit C; K10745 ribonuclease H2 subunit C (A)"	DNA replication (ko03030)	--	--	Ribonuclease H2 non-catalytic subunit (Ylr154p-like)	Ribonuclease H2 subunit C GN=RNASEH2C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ribonuclease H2 subunit C [Ailuropoda melanoleuca] 
ENSG00000172927(MYEOV)	--	19.86542	760	27.23415	1056	27.00221	1038	39.01233	1470	25.305851	949	21.16749	806	1.05E-05	0.91955319	normal	0.964392628	-0.175291437	normal	0.788778885	-0.37262834	normal	0.806387137	0.153332338	normal	--	--	--	--	--	--	--	--	Myeloma-overexpressed gene protein GN=MYEOV OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	--
ENSG00000172932(ANKRD13D)	--	11.31540201	454	10.87088701	463	10.85606425	453	7.228505465	349	8.39589601	399	9.556820347	454	0.725605477	-0.408714699	normal	0.933077053	-0.235221483	normal	0.970887156	-0.005093211	normal	0.407844355	-0.209151841	normal	--	--	--	--	--	[R]	General function prediction only	GPCR-chaperone;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 13D GN=ANKRD13D OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 13D [Ceratotherium simum simum]
ENSG00000172935(MRGPRF)	--	0.02854046	1	0	0	0.0818247	2	0	0	0	0	0.0280491	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08394|0|hsa:116535|MRGPRF, GPR140, GPR168, MRGF, RTA; MAS-related GPR, member F; K08394 Mas-related G protein-coupled receptor member F (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Mas-related G-protein coupled receptor member F GN=MRGPRF OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: mas-related G-protein coupled receptor member F isoform X1 [Equus caballus] 
ENSG00000172936(MYD88)	--	12.38676807	646	13.98589825	738	13.87806095	765	17.31087465	909	17.35791602	904	14.20664019	773	0.503409067	0.460985675	normal	0.92202126	0.270773341	normal	0.976554475	0.00670404	normal	0.207450642	0.245581879	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K04729|0|ptr:460269|MYD88; myeloid differentiation primary response 88; K04729 myeloid differentiation primary response protein MyD88 (A)	NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Toll-like receptor signaling pathway (ko04620);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Malaria (ko05144);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	--	--	TIR domain;; Death domain;; TIR domain	Myeloid differentiation primary response protein MyD88 GN=MYD88 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: myeloid differentiation primary response protein MyD88 [Galeopterus variegatus]
ENSG00000172938(MRGPRD)	--	0	0	0	0	0	0	0.167884	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08392|1.6969e-176|hsa:116512|MRGPRD, MRGD, TGR7; MAS-related GPR, member D; K08392 Mas-related G protein-coupled receptor member D (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Mas-related G-protein coupled receptor member D GN=MRGPRD OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: mas-related G-protein coupled receptor member D [Trichechus manatus latirostris]
ENSG00000172939(OXSR1)	--	16.587286	1427	17.685434	1539	17.38460308	1497	20.19420251	1749	16.37810461	1405	16.471057	1416	0.943741162	0.262457096	normal	0.974626807	-0.152692555	normal	0.981181241	-0.088452508	normal	0.970604033	0.012270718	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08835|0|hsa:9943|OXSR1, OSR1; oxidative stress responsive 1 (EC:2.7.11.1); K08835 serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Oxidative-stress-responsive kinase 1 C terminal	Serine/threonine-protein kinase OSR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase OSR1 isoform X1 [Equus caballus] 
ENSG00000172940(SLC22A13)	--	0.0218789	1	0.0433619	2	0.0639434	2	0.0218645	1	0.0213196	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08209|0|hsa:9390|SLC22A13, OAT10, OCTL1, OCTL3, ORCTL-3, ORCTL3; solute carrier family 22 (organic anion/urate transporter), member 13; K08209 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 13 (A)"	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 13 GN=SLC22A13 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: solute carrier family 22 member 13 isoform X1 [Ursus maritimus]
ENSG00000172943(PHF8)	--	4.95221117	598	5.11324886	645	4.992029918	603	5.67324522	685	6.13098971	675	5.79945662	652	0.960044715	0.164730585	normal	0.973316822	0.044060798	normal	0.969245587	0.10417122	normal	0.699370949	0.102827819	normal	--	--	--	"K11445|0|hsa:23133|PHF8, JHDM1F, MRXSSD, ZNF422; PHD finger protein 8 (EC:1.14.11.27); K11445 JmjC domain-containing histone demethylation protein 1D/E/F (A)"	--	[B]	Chromatin structure and dynamics	"JmjC domain, hydroxylase;; Cupin-like domain;; PHD-finger"	Histone lysine demethylase PHF8 GN=PHF8 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone lysine demethylase PHF8 isoform X2 [Vicugna pacos]
ENSG00000172954(LCLAT1)	--	17.41879	934	19.9064886	1181	25.994854	1015	16.23109933	893	14.40838388	816	16.98881703	826	0.974741793	-0.09543406	normal	0.16860484	-0.553935893	normal	0.894966464	-0.305052713	normal	0.059113826	-0.32575198	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13513|0|ptr:459129|LCLAT1, LYCAT; lysocardiolipin acyltransferase 1; K13513 lysocardiolipin and lysophospholipid acyltransferase [EC:2.3.1.- 2.3.1.51] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Acyltransferase	Lysocardiolipin acyltransferase 1 GN=LCLAT1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: lysocardiolipin acyltransferase 1 [Ochotona princeps]
ENSG00000172955(ADH6)	--	0	0	0.044703075	2	0	0	0.167148416	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Biological Process: oxidation-reduction process (GO:0055114);; 	K13952|0|pps:100970400|ADH6; alcohol dehydrogenase 6 (class V); K13952 alcohol dehydrogenase 6 [EC:1.1.1.1] (A)	Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase	Alcohol dehydrogenase 6 GN=ADH6 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: alcohol dehydrogenase 6 [Ceratotherium simum simum]
ENSG00000172967(XKR3)	--	0	0	0	0	0	0	0	0	0	0	0.0828579	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	XK-related protein	XK-related protein 3 GN=XKR3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: XK-related protein 3, partial [Equus przewalskii]"
ENSG00000172977(KAT5)	--	11.70503687	426	11.71561	455	10.83384095	401	10.47826873	418	11.65935448	417	13.08996249	491	0.968628178	-0.057971668	normal	0.958606476	-0.146736068	normal	0.906184401	0.282863756	normal	0.948073478	0.027782638	normal	[B]	Chromatin structure and dynamics	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	K11304|0|mcf:102125755|KAT5; K(lysine) acetyltransferase 5; K11304 histone acetyltransferase HTATIP [EC:2.3.1.48] (A)	HTLV-I infection (ko05166)	[B]	Chromatin structure and dynamics	MOZ/SAS family;; RNA binding activity-knot of a chromodomain	Histone acetyltransferase KAT5 GN=KAT5 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone acetyltransferase KAT5 isoform 1 [Orcinus orca] 
ENSG00000172985(SH3RF3)	--	1.06525	124	0.68053	80	0.934479	110	0.146938	17	0.18468	21	0.128289	15	4.64E-14	-2.789033811	down	2.32E-05	-1.876813073	down	1.69E-12	-2.763446288	down	1.17E-10	-2.587864893	down	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	"K12171|0|hsa:344558|SH3RF3, POSH2, SH3MD4; SH3 domain containing ring finger 3; K12171 E3 ubiquitin-protein ligase SH3RF [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	SH3 domain-containing RING finger protein 3 GN=SH3RF3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: SH3 domain-containing RING finger protein 3 [Odobenus rosmarus divergens]
ENSG00000172992(DCAKD)	--	15.927122	492	16.57164	473	17.198826	528	15.033348	432	12.931432	398	15.482563	453	0.941020333	-0.21773297	normal	0.915024125	-0.269557431	normal	0.937380692	-0.228610673	normal	0.311324218	-0.239607675	normal	[H]	Coenzyme transport and metabolism	Molecular Function: dephospho-CoA kinase activity (GO:0004140);; Molecular Function: ATP binding (GO:0005524);; Biological Process: coenzyme A biosynthetic process (GO:0015937);; 	--	--	[H]	Coenzyme transport and metabolism	Dephospho-CoA kinase	Dephospho-CoA kinase domain-containing protein GN=DCAKD OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: dephospho-CoA kinase domain-containing protein [Pteropus alecto] 
ENSG00000172995(ARPP21)	--	0.355355796	19	0.0794212	5	0.23346052	14	0.0480152	3	0.106462173	6	0.157359077	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	R3H domain	cAMP-regulated phosphoprotein 21 GN=ARPP21 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: cAMP-regulated phosphoprotein 21 isoform 2 [Ceratotherium simum simum]
ENSG00000173011(TADA2B)	--	5.347757351	425	5.581441487	426	6.799087385	429	6.454674071	516	6.735542229	483	6.23565723	477	0.927546586	0.248260457	normal	0.956647314	0.159212144	normal	0.960227801	0.144237779	normal	0.475738105	0.184122645	normal	--	--	--	K15127|0|ptr:471134|TADA2B; transcriptional adaptor 2B; K15127 transcriptional adapter 2-beta (A)	--	[B]	Chromatin structure and dynamics	"Myb-like DNA-binding domain;; Zinc finger, ZZ type;; Myb-like DNA-binding domain"	Transcriptional adapter 2-beta GN=TADA2B OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: transcriptional adapter 2-beta [Orcinus orca]
ENSG00000173013(CCDC96)	--	0.64091	31	0.687103	35	1.39001	71	1.08024	53	0.822153	39	0.9422	46	0.863453787	0.715493545	normal	0.98027813	0.129394568	normal	0.845027848	-0.617997836	normal	1	-0.009799356	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4201)	Coiled-coil domain-containing protein 96 GN=CCDC96 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 96 [Galeopterus variegatus]
ENSG00000173020(GRK2)	--	15.7990047	1082	16.0239018	1119	17.122002	1208	15.75060269	1078	14.02120377	956	14.26750163	980	0.979966725	-0.036124193	normal	0.940622986	-0.248190742	normal	0.895226094	-0.309627063	normal	0.304117219	-0.199025527	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K00910|0|ptr:451363|ADRBK1; adrenergic, beta, receptor kinase 1; K00910 beta-adrenergic-receptor kinase [EC:2.7.11.15] (A)"	Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Glutamatergic synapse (ko04724);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Regulator of G protein signaling domain;; PH domain	Beta-adrenergic receptor kinase 1 GN=ADRBK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: beta-adrenergic receptor kinase 1 [Oryctolagus cuniculus]
ENSG00000173039(RELA)	--	31.34435243	1603	32.76028413	1617	31.17347934	1526	37.49950802	1841	33.20280817	1618	37.35186181	1774	0.974813799	0.168731946	normal	0.984324919	-0.020515448	normal	0.965676734	0.208767553	normal	0.575638874	0.11947327	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04735|0|pon:100456049|RELA; v-rel avian reticuloendotheliosis viral oncogene homolog A; K04735 transcription factor p65 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Cocaine addiction (ko05030);; Salmonella infection (ko05132);; Pertussis (ko05133);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; Pancreatic cancer (ko05212);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Inflammatory bowel disease (IBD) (ko05321)	--	--	Rel homology domain (RHD)	Transcription factor p65 GN=RELA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor p65 [Camelus bactrianus]
ENSG00000173040(EVC2)	--	1.097593624	111	1.161348226	120	1.271789731	131	1.525228523	154	1.689148672	169	1.350809853	136	0.843156247	0.43639075	normal	0.785149519	0.46757528	normal	0.967915823	0.045235857	normal	0.414546265	0.321252699	normal	--	--	Biological Process: smoothened signaling pathway (GO:0007224);; 	--	--	--	--	Ellis van Creveld protein 2 like protein	Limbin (Precursor) GN=EVC2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: limbin [Tupaia chinensis]
ENSG00000173041(ZNF680)	--	3.987199	149	3.539744452	150	5.187837562	199	3.84970369	172	4.158724303	173	3.58347972	136	0.956196796	0.174587397	normal	0.953307172	0.182667029	normal	0.554954772	-0.55234469	normal	0.89361351	-0.071388156	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|nle:100603397|ZNF680; zinc finger protein 680; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Domain of unknown function (DUF1610);; C1-like domain"	Zinc finger protein 680 GN=ZNF680 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000173064(HECTD4)	--	7.36763806	2271	7.616601266	2334	7.37967	2332	7.53343814	2371	7.292111559	2245	8.2707153	2631	0.987963654	0.031314959	normal	0.986260012	-0.077464492	normal	0.980593358	0.165650827	normal	0.877313217	0.042180652	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; 	K17849|0|ptr:452261|HECTD4; HECT domain containing E3 ubiquitin protein ligase 4; K17849 E3 ubiquitin-protein ligase HECTD4 [EC:6.3.2.19] (A)	--	--	--	HECT-domain (ubiquitin-transferase)	Probable E3 ubiquitin-protein ligase HECTD4 GN=HECTD4 OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase HECTD4 isoform X5 [Bos taurus] 
ENSG00000173065(FAM222B)	--	11.77465604	676	14.25888299	760	13.04131266	802	14.09498426	786	11.75323254	772	13.29931706	861	0.956757808	0.186280898	normal	0.97590569	0.001172556	normal	0.973742019	0.093948553	normal	0.725058255	0.091446449	normal	--	--	--	--	--	--	--	Protein family of FAM222A	Protein FAM222B GN=FAM222B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM222B isoform X1 [Galeopterus variegatus]
ENSG00000173068(BNC2)	--	3.215761328	361	4.009202089	327	3.312585785	333	6.33180918	661	6.16443754	722	6.66902	591	0.000568103	0.839142541	normal	2.20E-07	1.117715331	up	0.00128409	0.816523747	normal	6.09E-08	0.929665215	normal	--	--	--	--	--	--	--	"C2H2-type zinc finger;; Zinc finger, C2H2 type;; Zinc-finger of C2H2 type"	Zinc finger protein basonuclin-2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein basonuclin-2 isoform X3 [Oryctolagus cuniculus]
ENSG00000173077(DEC1)	--	0	0	0	0	0	0	0.0398957	1	0.196399	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Deleted in esophageal cancer 1 GN=DEC1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: deleted in esophageal cancer 1, partial [Galeopterus variegatus]"
ENSG00000173080(RXFP4)	--	0	0	0	0	0	0	0.0680849	1	0.0676119	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08398|0|hsa:339403|RXFP4, GPCR142, GPR100, RLN3R2, RXFPR4; relaxin/insulin-like family peptide receptor 4; K08398 relaxin family peptide receptor 4 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Relaxin-3 receptor 2 GN=RXFP4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: relaxin-3 receptor 2 [Galeopterus variegatus]
ENSG00000173083(HPSE)	--	1.761854293	110	1.617322356	101	0.810444965	57	0.28082514	20	0.562557389	36	0.336078641	24	1.89E-10	-2.402181794	down	0.000274926	-1.471198314	down	0.164222905	-1.205485891	normal	0.000947641	-1.765576363	down	--	--	"Cellular Component: membrane (GO:0016020);; Molecular Function: hydrolase activity, acting on glycosyl bonds (GO:0016798);; "	"K07964|0|hsa:10855|HPSE, HPA, HPA1, HPR1, HPSE1, HSE1; heparanase (EC:3.2.1.166); K07964 heparanase 1 [EC:3.2.1.166] (A)"	Glycosaminoglycan degradation (ko00531);; Proteoglycans in cancer (ko05205)	--	--	"Glycosyl hydrolase family 79, N-terminal domain"	Heparanase 50 kDa subunit (Precursor) GN=HPSE OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: heparanase isoform 1 [Trichechus manatus latirostris]
ENSG00000173085(COQ2)	--	17.339207	387	19.18499	434	15.65631	350	19.240213	437	16.755514	373	20.93417	465	0.959328845	0.143929507	normal	0.931125931	-0.239046466	normal	0.74607594	0.400079791	normal	0.747864759	0.101378938	normal	[H]	Coenzyme transport and metabolism	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring alkyl or aryl (other than methyl) groups (GO:0016765);; "	"K06125|0|hsa:27235|COQ2, CL640, COQ10D1, MSA1; coenzyme Q2 4-hydroxybenzoate polyprenyltransferase (EC:2.5.1.39); K06125 4-hydroxybenzoate polyprenyltransferase [EC:2.5.1.39] (A)"	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130)	[H]	Coenzyme transport and metabolism	UbiA prenyltransferase family	"4-hydroxybenzoate polyprenyltransferase, mitochondrial (Precursor) GN=COQ2 OS=Homo sapiens (Human) PE=1 SV=1"	H	Coenzyme transport and metabolism	"PREDICTED: 4-hydroxybenzoate polyprenyltransferase, mitochondrial [Trichechus manatus latirostris]"
ENSG00000173093(CCDC63)	--	0	0	0	0	0	0	0	0	0	0	0.020227	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 63 GN=CCDC63 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 63 [Tupaia chinensis]
ENSG00000173110(HSPA6)	--	0.410079	20	0.0992815	5	0.214522	10	0.367697	18	0.239725	11	0.142212	7	0.988883247	-0.169132097	normal	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	K03283|0|hsa:3310|HSPA6; heat shock 70kDa protein 6 (HSP70B'); K03283 heat shock 70kDa protein 1/8 (A)	Spliceosome (ko03040);; MAPK signaling pathway (ko04010);; Protein processing in endoplasmic reticulum (ko04141);; Endocytosis (ko04144);; Antigen processing and presentation (ko04612);; Estrogen signaling pathway (ko04915);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Measles (ko05162);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein;; MreB/Mbl protein	Heat shock 70 kDa protein 6 GN=HSPA6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 6 [Tupaia chinensis] 
ENSG00000173113(TRMT112)	--	134.4451725	1703	123.9625581	1655	136.1074293	1787	137.2072143	1822	141.6972821	1742	128.814699	1711	0.984386298	0.066554206	normal	0.984145316	0.052440141	normal	0.98415363	-0.070929966	normal	0.964739885	0.014734188	normal	--	--	--	K15448|1.44431e-85|pps:100990347|TRMT112; tRNA methyltransferase 11-2 homolog (S. cerevisiae); K15448 multifunctional methyltransferase subunit TRM112 (A)	--	[S]	Function unknown	Trm112p-like protein	Multifunctional methyltransferase subunit TRM112-like protein GN=TRMT112 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: tRNA methyltransferase 112 homolog [Odobenus rosmarus divergens] 
ENSG00000173114(LRRN3)	--	0.019180097	1	0.058155469	3	0	0	0.1820118	10	0.194549	11	0.21573576	13	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Leucine Rich Repeat;; Fibronectin type III domain;; Immunoglobulin domain;; Leucine rich repeat N-terminal domain;; Leucine rich repeat	Leucine-rich repeat neuronal protein 3 (Precursor) GN=LRRN3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat neuronal protein 3 [Ceratotherium simum simum]
ENSG00000173120(KDM2A)	--	18.67717	2340	20.64244574	2580	20.30801005	2449	18.5293898	2372	17.430692	2198	17.16291783	2237	0.9882967	-0.01122946	normal	0.959968462	-0.25244572	normal	0.982828962	-0.138829226	normal	0.508742812	-0.135868006	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	"K10276|0|ptr:451362|KDM2A, FBXL11; lysine (K)-specific demethylase 2A; K10276 F-box and leucine-rich repeat protein 10/11 [EC:1.14.11.27] (A)"	--	[B]	Chromatin structure and dynamics	"CXXC zinc finger domain;; F-box domain;; F-box-like;; JmjC domain, hydroxylase"	Lysine-specific demethylase 2A GN=KDM2A OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: lysine-specific demethylase 2A isoform X1 [Eptesicus fuscus]
ENSG00000173137(ADCK5)	--	5.88294	189	4.31853	144	4.90847	165	6.1164	198	4.56055	146	5.22826	169	0.966581406	0.035996039	normal	0.966745916	-0.001511239	normal	0.967165591	0.026030043	normal	0.976471761	0.021041771	normal	[R]	General function prediction only	--	K08869|0|hsa:203054|ADCK5; aarF domain containing kinase 5; K08869 aarF domain-containing kinase (A)	--	[R]	General function prediction only	ABC1 family	Uncharacterized aarF domain-containing protein kinase 5 GN=ADCK5 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: uncharacterized aarF domain-containing protein kinase 5 [Ceratotherium simum simum]
ENSG00000173141(MRPL57)	--	14.0874	584	12.702	539	13.6074	573	14.4137	608	13.4015	555	12.8819	541	0.973260424	0.027200557	normal	0.971824053	0.020718655	normal	0.969151732	-0.090950908	normal	0.972791873	-0.01471985	normal	--	--	Cellular Component: mitochondrial ribosome (GO:0005761);; 	--	--	--	--	Mitochondrial ribosome protein 63	"Ribosomal protein 63, mitochondrial GN=MRPL57 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: ribosomal protein 63, mitochondrial [Trichechus manatus latirostris]"
ENSG00000173145(NOC3L)	--	14.046055	912	14.86867019	955	15.4664204	979	12.267764	803	11.10642991	718	12.08032	784	0.950851078	-0.214081398	normal	0.626777309	-0.432151279	normal	0.866292413	-0.328178933	normal	0.065090609	-0.325401629	normal	[JU]	"Translation, ribosomal structure and biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	--	"K14834|0|hsa:64318|NOC3L, AD24, C10orf117, FAD24; nucleolar complex associated 3 homolog (S. cerevisiae); K14834 nucleolar complex protein 3 (A)"	--	[JU]	"Translation, ribosomal structure and biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	CBF/Mak21 family;; Nucleolar complex-associated protein	Nucleolar complex protein 3 homolog GN=NOC3L OS=Homo sapiens (Human) PE=1 SV=1	JU	"Translation, ribosomal structure and biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: nucleolar complex protein 3 homolog [Vicugna pacos]
ENSG00000173153(ESRRA)	--	32.22654975	994	25.54347978	962	28.571666	1087	33.8470272	1181	35.2249567	1163	33.4641556	1085	0.95426108	0.21755016	normal	0.939269124	0.251955061	normal	0.980517919	-0.010933115	normal	0.47361543	0.151064358	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K08552|0|mcc:722085|steroid hormone receptor ERR1-like; K08552 estrogen-related receptor alpha (A)	--	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Steroid hormone receptor ERR1 GN=ESRRA OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: steroid hormone receptor ERR1 isoform X6 [Capra hircus] 
ENSG00000173156(RHOD)	--	9.859040933	162	13.585482	227	10.58600054	183	21.37683	352	23.72240039	391	23.513396	386	1.93E-05	1.081626169	up	0.0148439	0.759151686	normal	1.73E-05	1.062283873	up	5.09E-06	0.9598995	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07530|2.63005e-145|pps:100991450|RHOD; ras homolog family member D; K07530 Ras homolog gene family, member D (A)"	Axon guidance (ko04360)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Rho-related GTP-binding protein RhoD (Precursor) GN=RHOD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoD [Galeopterus variegatus]
ENSG00000173157(ADAMTS20)	--	0	0	0	0	0.021742385	0	0.043477345	2	0.01108117	0	0.051716389	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; 	"K09609|0|hsa:80070|ADAMTS20, ADAM-TS20, ADAMTS-20, GON-1; ADAM metallopeptidase with thrombospondin type 1 motif, 20; K09609 a disintegrin and metalloproteinase with thrombospondin motifs 20 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	GON domain;; Thrombospondin type 1 domain;; Reprolysin family propeptide;; ADAM-TS Spacer 1;; Reprolysin (M12B) family zinc metalloprotease;; Metallo-peptidase family M12;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like;; Metallo-peptidase family M12B Reprolysin-like	A disintegrin and metalloproteinase with thrombospondin motifs 20 (Precursor) GN=ADAMTS20 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: A disintegrin and metalloproteinase with thrombospondin motifs 20 [Ceratotherium simum simum]
ENSG00000173163(COMMD1)	--	25.61686313	358	32.12048016	454	30.05233237	427	20.86004264	298	21.8451418	300	20.033858	280	0.900901248	-0.294093754	normal	0.121627696	-0.616610428	normal	0.12750683	-0.614393218	normal	0.015963294	-0.51819493	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 1 GN=COMMD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COMM domain-containing protein 1 [Tupaia chinensis]
ENSG00000173166(RAPH1)	--	5.708719535	766	5.331871347	755	4.94687933	732	3.838738668	583	3.621312982	554	4.310845855	701	0.645826679	-0.423703142	normal	0.507839538	-0.466920668	normal	0.973630775	-0.070571644	normal	0.098007254	-0.314443038	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain;; PH domain	Ras-associated and pleckstrin homology domains-containing protein 1 GN=RAPH1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ras-associated and pleckstrin homology domains-containing protein 1 [Loxodonta africana]
ENSG00000173171(MTX1)	--	35.64845	684	32.34736	653	33.86432	651	30.55992	612	33.68832	643	30.74337	598	0.953732307	-0.19084342	normal	0.973122752	-0.043589081	normal	0.965934638	-0.130487122	normal	0.630235954	-0.122715524	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: protein targeting to mitochondrion (GO:0006626);; 	"K17776|0|hsa:4580|MTX1, MTX, MTXN; metaxin 1; K17776 metaxin (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Tom37 C-terminal domain;; Outer mitochondrial membrane transport complex protein;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain"	Metaxin-1 GN=MTX1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: metaxin-1 [Oryctolagus cuniculus]
ENSG00000173175(ADCY5)	--	0.211754606	18	0.114619428	16	0.117304315	16	0.160452255	22	0.330429671	30	0.100977922	14	0.987603894	0.24011464	normal	0.92947482	0.827559754	normal	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: adenylate cyclase activity (GO:0004016);; Cellular Component: plasma membrane (GO:0005886);; Biological Process: cAMP biosynthetic process (GO:0006171);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	K08045|0|nle:100580455|ADCY5; adenylate cyclase 5; K08045 adenylate cyclase 5 [EC:4.6.1.1] (A)	Purine metabolism (ko00230);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Alcoholism (ko05034);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[C]	Energy production and conversion	Adenylate and Guanylate cyclase catalytic domain;; Domain of Unknown Function (DUF1053)	Adenylate cyclase type 5 GN=ADCY5 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	adenylate cyclase type 5 [Bos taurus]
ENSG00000173193(PARP14)	--	6.233235824	992	6.981883	1125	6.672655828	1063	10.04415962	1623	10.5547504	1697	11.01689087	1776	0.009671975	0.678589452	normal	0.121729348	0.571005967	normal	0.002345195	0.731384904	normal	3.55E-06	0.659409661	normal	[R]	General function prediction only	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15261|0|hsa:54625|PARP14, ARTD8, BAL2, PARP-14, pART8; poly (ADP-ribose) polymerase family, member 14 (EC:2.4.2.30); K15261 poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30] (A)"	--	--	--	Macro domain;; Poly(ADP-ribose) polymerase catalytic domain;; WWE domain	Poly [ADP-ribose] polymerase 14 GN=PARP14 OS=Homo sapiens (Human) PE=1 SV=3	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: poly [ADP-ribose] polymerase 14 [Galeopterus variegatus]
ENSG00000173200(PARP15)	--	0.267807308	19	0.309326884	22	0.506602539	35	0.450817848	32	0.493130034	35	0.448881022	32	0.954073675	0.67856999	normal	0.952428911	0.61467341	normal	0.982542064	-0.13162454	normal	0.65235772	0.361289591	normal	[R]	General function prediction only	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15261|0|hsa:165631|PARP15, ARTD7, BAL3, pART7; poly (ADP-ribose) polymerase family, member 15 (EC:2.4.2.30); K15261 poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30] (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	Macro domain;; Poly(ADP-ribose) polymerase catalytic domain	Poly [ADP-ribose] polymerase 15 GN=PARP15 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: poly [ADP-ribose] polymerase 15 isoform X6 [Canis lupus familiaris]
ENSG00000173207(CKS1B)	--	226.81333	1972	200.91825	1775	222.80517	2042	204.11946	1941	199.12301	1735	200.61163	1876	0.985903472	-0.053649564	normal	0.984436431	-0.054263156	normal	0.98145254	-0.130513603	normal	0.726808553	-0.081467434	normal	--	--	--	K02219|3.27659e-42|cge:103160037|cyclin-dependent kinases regulatory subunit 1-like; K02219 cyclin-dependent kinase regulatory subunit CKS1 (A)	Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cyclin-dependent kinase regulatory subunit	Cyclin-dependent kinases regulatory subunit 1 GN=CKS1B OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinases regulatory subunit 1 [Monodelphis domestica]
ENSG00000173208(ABCD2)	--	0.0212523	2	0.042493	4	0.0427601	3	0	0	0	0	0.0105349	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05676|0|hsa:225|ABCD2, ABC39, ALDL1, ALDR, ALDRP, hALDR; ATP-binding cassette, sub-family D (ALD), member 2; K05676 ATP-binding cassette, subfamily D (ALD), member 2 (A)"	ABC transporters (ko02010);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	ABC transporter transmembrane region 2;; ABC transporter	ATP-binding cassette sub-family D member 2 GN=ABCD2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: ATP-binding cassette sub-family D member 2 [Ceratotherium simum simum]
ENSG00000173209(AHSA2)	--	20.371364	1820	21.08615701	1888	20.17806119	1640	11.680301	1022	12.79103059	1180	15.07219609	1197	4.60E-05	-0.862389485	normal	0.006801884	-0.698783537	normal	0.500845196	-0.462063241	normal	1.72E-06	-0.674793666	normal	--	--	--	--	--	[S]	Function unknown	--	Activator of 90 kDa heat shock protein ATPase homolog 2 GN=AHSA2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: activator of 90 kDa heat shock protein ATPase homolog 2 [Camelus ferus]
ENSG00000173210(ABLIM3)	--	3.99968888	349	2.72165945	245	4.00739842	349	10.51849217	923	9.9837823	851	7.238300428	617	4.52E-12	1.368426581	up	0	1.768719227	up	0.001312535	0.811073816	normal	4.63E-06	1.320342435	up	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	"K07520|0|hsa:22885|ABLIM3; actin binding LIM protein family, member 3; K07520 actin-binding LIM protein (A)"	Axon guidance (ko04360)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain;; Villin headpiece domain	Actin-binding LIM protein 3 GN=ABLIM3 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: actin-binding LIM protein 3 isoform X1 [Pteropus alecto]
ENSG00000173212(MAB21L3)	--	0.111182	7	0.0939264	6	0.0311448	1	0.126807	8	0.154735	9	0.142009	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Mab-21 protein	Protein mab-21-like 3 GN=MAB21L3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein mab-21-like 3 [Oryctolagus cuniculus] 
ENSG00000173214(MFSD4B)	--	1.843379	185	1.803643	183	2.08579	208	1.3527429	135	1.337591	136	1.534384	154	0.738888675	-0.480703152	normal	0.796869624	-0.445377287	normal	0.785618702	-0.438227481	normal	0.149569153	-0.459184746	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08175|0|hsa:91749|MFSD4B, NaGLT1; KIAA1919; K08175 MFS transporter, FHS family, Na+ dependent glucose transporter 1 (A)"	--	--	--	Major Facilitator Superfamily	Sodium-dependent glucose transporter 1 GN=NAGLT1 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: sodium-dependent glucose transporter 1 [Bos mutus]
ENSG00000173218(VANGL1)	--	12.72207885	1157	12.45042721	1134	11.3860326	1110	11.20021563	1134	13.75170038	1218	10.89484131	923	0.979829405	-0.059720378	normal	0.978559931	0.081561972	normal	0.92426565	-0.274038518	normal	0.761520447	-0.076204723	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: integral component of membrane (GO:0016021);; 	K04510|0|ptr:457149|VANGL1; VANGL planar cell polarity protein 1; K04510 vang-like (A)	Wnt signaling pathway (ko04310)	[T]	Signal transduction mechanisms	Strabismus protein	Vang-like protein 1 GN=VANGL1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vang-like protein 1 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000173221(GLRX)	--	39.96942	696	44.6850319	692	52.11429	778	41.090846	614	33.063456	522	53.003841	774	0.947372047	-0.211184136	normal	0.652562682	-0.427070292	normal	0.976579022	-0.015697439	normal	0.461168627	-0.201802501	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Biological Process: cell redox homeostasis (GO:0045454);; 	K03676|1.81233e-71|ptr:736317|GLRX; glutaredoxin (thioltransferase) (EC:1.8.4.1); K03676 glutaredoxin 3 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Glutaredoxin;; Glutaredoxin-like domain (DUF836)	Glutaredoxin-1 GN=GLRX OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutaredoxin-1 [Galeopterus variegatus]
ENSG00000173226(IQCB1)	--	11.49624266	546	13.00121799	564	10.48811026	482	13.97302382	584	14.63032857	657	13.66851318	646	0.971043775	0.066055414	normal	0.95035802	0.198278682	normal	0.689444927	0.413086223	normal	0.312683427	0.224150612	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16774|0|hsa:9657|IQCB1, NPHP5, PIQ, SLSN5; IQ motif containing B1; K16774 IQ calmodulin-binding motif-containing protein 1 (A)"	--	[Z]	Cytoskeleton	IQ calmodulin-binding motif	IQ calmodulin-binding motif-containing protein 1 GN=IQCB1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: IQ calmodulin-binding motif-containing protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000173227(SYT12)	--	4.11935407	293	2.758540565	207	2.613100551	216	2.7169487	188	3.13304319	223	1.7473688	124	0.112263865	-0.666597665	normal	0.962917135	0.085385305	normal	0.037844109	-0.801480956	normal	0.283310357	-0.442694433	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-12 GN=SYT12 OS=Homo sapiens (Human) PE=2 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-12 [Panthera tigris altaica]
ENSG00000173230(GOLGB1)	--	11.88717011	3274	14.24377331	4044	14.9084843	3720	15.06574886	4299	15.4202193	4397	15.8087866	4518	0.890414147	0.361965902	normal	0.990549456	0.099274368	normal	0.965415921	0.271989726	normal	0.177242939	0.23854025	normal	--	--	--	--	--	--	--	--	Golgin subfamily B member 1 GN=GOLGB1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: golgin subfamily B member 1 isoform 1 [Ceratotherium simum simum]
ENSG00000173237(C11orf86)	--	5.82554	125	2.99062	68	3.66422	84	7.37847	160	5.88037	123	3.76003	85	0.918414008	0.321808192	normal	0.195342849	0.819884815	normal	0.972554874	0.008627661	normal	0.535298568	0.38665515	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4633)	Uncharacterized protein C11orf86 GN=C11orf86 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C11orf86 homolog [Loxodonta africana]
ENSG00000173239(LIPM)	--	0.0521881	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Biological Process: lipid metabolic process (GO:0006629);; 	--	--	[I]	Lipid transport and metabolism	alpha/beta hydrolase fold;; Partial alpha/beta-hydrolase lipase region;; Alpha/beta hydrolase family;; Alpha/beta hydrolase family	Lipase member M (Precursor) GN=LIPM OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: lipase member M [Galeopterus variegatus]
ENSG00000173250(GPR151)	--	0	0	0	0	0	0	0	0	0	0	0.020183	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08435|0|hsa:134391|GPR151, GALR4, GALRL, GPCR, PGR7; G protein-coupled receptor 151; K08435 G protein-coupled receptor 151 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 151 GN=GPR151 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 151 [Equus przewalskii]
ENSG00000173253(DMRT2)	--	0.057090344	1	0	0	0	0	0	0	0.035628619	0	0.056133974	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	DM DNA binding domain	Doublesex- and mab-3-related transcription factor 2 GN=DMRT2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: doublesex- and mab-3-related transcription factor 2 isoform X1 [Pteropus alecto] 
ENSG00000173258(ZNF483)	--	1.205890026	66	1.0408889	55	0.943419	70	0.857324274	43	1.324689399	63	0.8560825	59	0.854260874	-0.630629235	normal	0.971581727	0.170120647	normal	0.965430169	-0.249063191	normal	0.725058255	-0.230990727	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09229|0|ggo:101146321|ZNF483; zinc finger protein 483; K09229 KRAB and SCAN domains-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 483 GN=ZNF483 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 483 [Galeopterus variegatus]
ENSG00000173261(PLAC8L1)	--	0.428578	3	0.281491	2	0.138648	0	0.139262	1	0.417824	2	0.420201	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PLAC8 family	PLAC8-like protein 1 GN=PLAC8L1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: PLAC8-like protein 1 [Galeopterus variegatus]
ENSG00000173262(SLC2A14)	--	0.073983901	3	0.041528448	1	0.205306955	4	1.018798777	41	1.438864685	51	0.67859256	23	8.49E-06	3.204010573	up	6.29E-10	4.370925315	up	0.190606238	2.145883984	normal	2.78E-06	3.824617312	up	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily;; Reduced folate carrier	"Solute carrier family 2, facilitated glucose transporter member 14 GN=SLC2A14 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	hypothetical protein PANDA_019307 [Ailuropoda melanoleuca]
ENSG00000173264(GPR137)	--	26.7312129	575	29.94546094	587	32.67510608	727	26.62994179	505	18.86757929	432	26.60028751	570	0.942531054	-0.217490144	normal	0.548367074	-0.462361306	normal	0.813857124	-0.358440655	normal	0.112872655	-0.346426023	normal	--	--	--	--	--	--	--	--	Integral membrane protein GPR137 GN=GPR137 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: integral membrane protein GPR137 isoform X6 [Equus caballus]
ENSG00000173267(SNCG)	--	8.751582	103	7.476886	92	6.79269	88	4.174807	51	6.377146	74	2.262516	27	0.048016163	-1.022769937	normal	0.94177162	-0.329483275	normal	0.000102643	-1.658503438	down	0.023670833	-0.919175013	normal	--	--	--	--	--	--	--	Synuclein	Gamma-synuclein GN=SNCG OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: gamma-synuclein [Oryctolagus cuniculus]
ENSG00000173269(MMRN2)	--	2.415754	104	1.140688939	47	1.516386846	65	0.719461629	33	0.537039312	25	0.332807277	16	1.98E-05	-1.641470982	down	0.751297633	-0.892170591	normal	0.000138831	-1.933092494	down	0.024713727	-1.568810798	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	C1q domain;; EMI domain	Multimerin-2 (Precursor) GN=MMRN2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: multimerin-2 [Sus scrofa]
ENSG00000173272(MZT2A)	--	110.124	827	102.469	821	99.0339	807	92.1213	728	87.111	655	93.5091	719	0.948989072	-0.214356308	normal	0.838738467	-0.3465974	normal	0.960544525	-0.174521651	normal	0.213702534	-0.24526847	normal	--	--	--	"K16574|4.37767e-82|hsa:653784|MZT2A, FAM128A, MOZART2A; mitotic spindle organizing protein 2A; K16574 mitotic-spindle organizing protein 2A/2B (A)"	--	--	--	Mitotic-spindle organizing gamma-tubulin ring associated	Mitotic-spindle organizing protein 2A GN=MZT2A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mitotic-spindle organizing protein 2B isoform 2 [Canis lupus familiaris]
ENSG00000173273(TNKS)	--	8.447721104	1390	9.804320641	1527	10.51781475	1436	9.455380369	1557	10.55018254	1641	10.39920655	1721	0.977449396	0.132713149	normal	0.982106322	0.082369919	normal	0.948733476	0.252656545	normal	0.435108402	0.155429089	normal	[R]	General function prediction only	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; Molecular Function: protein binding (GO:0005515);; 	"K10799|0|hsa:8658|TNKS, ARTD5, PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1, pART5; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase (EC:2.4.2.30); K10799 tankyrase [EC:2.4.2.30] (A)"	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Poly(ADP-ribose) polymerase catalytic domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Tankyrase-1 GN=TNKS OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: tankyrase-1 [Equus caballus]
ENSG00000173275(ZNF449)	--	3.401962925	245	3.629722506	259	4.750050153	294	2.6199584	196	2.361643468	183	4.22918879	267	0.871045681	-0.350298317	normal	0.549586713	-0.518911083	normal	0.957381951	-0.146476887	normal	0.257269258	-0.324872505	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:203523|ZNF449, ZSCAN19; zinc finger protein 449; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 449 GN=ZNF449 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 449 [Tupaia chinensis]
ENSG00000173276(ZBTB21)	--	4.956940005	527	6.825422	664	5.144132	543	5.57904634	549	4.477903438	468	6.41773863	627	0.97213518	0.028090686	normal	0.30482938	-0.524670093	normal	0.950205955	0.198706391	normal	0.760434294	-0.097964563	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 21 GN=ZBTB21 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 21 isoform X1 [Galeopterus variegatus]
ENSG00000173281(PPP1R3B)	--	4.03292065	399	4.953997862	491	4.494255	425	4.55402264	450	5.834665	559	8.86644318	877	0.959856503	0.14218823	normal	0.956929748	0.165221523	normal	9.11E-07	1.034205552	up	0.372610051	0.500947861	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: starch binding (GO:2001070);; 	"K07189|0|hsa:79660|PPP1R3B, GL, PPP1R4, PTG; protein phosphatase 1, regulatory subunit 3B; K07189 protein phosphatase 1 regulatory subunit 3A/B/C/D/E (A)"	Insulin signaling pathway (ko04910)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Putative phosphatase regulatory subunit	Protein phosphatase 1 regulatory subunit 3B GN=PPP1R3B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 3B [Orycteropus afer afer]
ENSG00000173320(STOX2)	--	2.260717251	407	3.0705908	513	1.911320507	344	1.446972511	279	2.106688406	307	1.71749555	299	0.230705145	-0.572966381	normal	0.007404519	-0.759220132	normal	0.943038267	-0.20956547	normal	0.046663948	-0.535739579	normal	--	--	--	--	--	[S]	Function unknown	Winged helix Storkhead-box1 domain	Storkhead-box protein 2 GN=STOX2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: storkhead-box protein 2 isoform X1 [Tupaia chinensis]
ENSG00000173327(MAP3K11)	--	20.7292176	1446	21.92441973	1508	21.60555551	1545	21.97493172	1524	24.21411055	1653	22.10843006	1509	0.983307466	0.044916598	normal	0.980149835	0.110917473	normal	0.983718361	-0.042263614	normal	0.892992905	0.03765464	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04419|0|hsa:4296|MAP3K11, MEKK11, MLK-3, MLK3, PTK1, SPRK; mitogen-activated protein kinase kinase kinase 11 (EC:2.7.11.25); K04419 mitogen-activated protein kinase kinase kinase 11 [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Mitogen-activated protein kinase kinase kinase 11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 11 [Ochotona princeps]
ENSG00000173334(TRIB1)	--	16.26695546	996	17.76933353	1055	14.83499327	904	16.55055189	996	17.55834068	1076	16.11119589	994	0.979151887	-0.030784775	normal	0.979813135	0.006998588	normal	0.971863023	0.128426684	normal	0.912673719	0.031815162	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08814|0|ggo:101130656|TRIB1; tribbles homolog 1; K08814 tribbles [EC:2.7.11.-] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Tribbles homolog 1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tribbles homolog 1 [Felis catus]
ENSG00000173338(KCNK7)	--	0.499727746	11	0.44976782	10	0.123018166	2	0.651167869	7	0.232569444	3	0.306900113	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04918|1.61291e-120|pps:100986184|KCNK7; potassium channel, subfamily K, member 7; K04918 potassium channel subfamily K member 7 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 7 GN=KCNK7 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 7 [Equus caballus]
ENSG00000173349(SFT2D3)	--	7.01944	372	5.62523	301	4.96879	264	5.62514	302	5.6306	300	5.33068	284	0.868165615	-0.330070053	normal	0.966577411	-0.026096214	normal	0.963411277	0.096528337	normal	0.777873668	-0.102469013	normal	--	--	Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	--	--	Got1/Sft2-like family	Vesicle transport protein SFT2C OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle transport protein SFT2C [Ceratotherium simum simum]
ENSG00000173366(RP11-330H6.5)	--	38.31468731	1192	33.18195556	1056	38.51467737	1235	51.1534293	1598	56.14703336	1745	41.52337618	1298	0.757750233	0.391613623	normal	0.006514116	0.702400404	normal	0.980895294	0.063412152	normal	0.040013062	0.392619281	normal	--	--	Molecular Function: actin binding (GO:0003779);; Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Biological Process: signal transduction (GO:0007165);; 	K10161|0|pps:100986336|TLR9; twinfilin-2; K10161 toll-like receptor 9 (A)	Toll-like receptor signaling pathway (ko04620);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Malaria (ko05144);; Tuberculosis (ko05152);; Measles (ko05162);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine Rich repeat;; Leucine rich repeat;; TIR domain;; Cofilin/tropomyosin-type actin-binding protein	Toll-like receptor 9 (Precursor) GN=TLR9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: toll-like receptor 9-like isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000173376(NDNF)	--	0.227644137	12	0.076389622	4	0.021372383	0	0.021334409	1	0.073438011	3	0.042349164	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2369);; Fibronectin type III domain	Protein NDNF (Precursor) GN=NDNF OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein NDNF-like isoform X2 [Sus scrofa]
ENSG00000173391(OLR1)	--	0.458043902	11	0.251663529	9	0.308173473	5	0.706609855	21	1.249591694	53	3.955250722	135	0.968616014	0.818238804	normal	5.01E-05	2.354917145	up	0	4.382439905	up	0.126856085	3.046108657	normal	--	--	--	K08763|3.97776e-175|pps:100994602|OLR1; oxidized low density lipoprotein (lectin-like) receptor 1; K08763 oxidised low-density lipoprotein receptor 1 (A)	PPAR signaling pathway (ko03320);; Phagosome (ko04145)	[TV]	Signal transduction mechanisms;; Defense mechanisms	"Lectin C-type domain;; UL45 protein;; Ly49-like protein, N-terminal region"	"Oxidized low-density lipoprotein receptor 1, soluble form GN=OLR1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	PREDICTED: oxidized low-density lipoprotein receptor 1 [Galeopterus variegatus]
ENSG00000173401(GLIPR1L1)	--	0	0	0.0745059	1	0	0	0.0976588	1	0.0971656	0	0.0731729	1	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family	GLIPR1-like protein 1 (Precursor) GN=GLIPR1L1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: GLIPR1-like protein 1 isoform X2 [Tupaia chinensis]
ENSG00000173402(DAG1)	--	45.91675667	4225	50.8301007	4854	44.2291043	4263	45.52252123	4500	46.09363128	4283	48.15461266	4507	0.992117766	0.060120211	normal	0.983544862	-0.201911967	normal	0.991866976	0.071982116	normal	0.926977546	-0.026979297	normal	--	--	Biological Process: cytoskeletal anchoring at plasma membrane (GO:0007016);; Cellular Component: dystrophin-associated glycoprotein complex (GO:0016010);; 	"K06265|0|hsa:1605|DAG1, 156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9; dystroglycan 1 (dystrophin-associated glycoprotein 1); K06265 dystroglycan 1 (A)"	ECM-receptor interaction (ko04512);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	[W]	Extracellular structures	Dystroglycan (Dystrophin-associated glycoprotein 1)	Beta-dystroglycan (Precursor) GN=DAG1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: dystroglycan isoform X1 [Physeter catodon] 
ENSG00000173409(ARV1)	--	22.08401	425	23.54693503	456	24.96462718	477	17.1493	339	15.72036787	305	14.188736	276	0.830943443	-0.35556696	normal	0.155425111	-0.599203866	normal	0.003643026	-0.794260066	normal	0.004081985	-0.583464255	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Arv1-like family	Protein ARV1 GN=ARV1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein ARV1 [Ailuropoda melanoleuca]
ENSG00000173418(NAA20)	--	80.66895	1298	91.45068	1491	78.55805	1272	110.315918	1773	102.07503	1625	84.890086	1371	0.679500965	0.41864441	normal	0.980614421	0.10263317	normal	0.979205119	0.099724234	normal	0.271441092	0.209719028	normal	[R]	General function prediction only	"Molecular Function: N-acetyltransferase activity (GO:0008080);; Molecular Function: transferase activity, transferring acyl groups other than amino-acyl groups (GO:0016747);; "	"K17972|8.63421e-130|pps:100978440|NAA20; N(alpha)-acetyltransferase 20, NatB catalytic subunit; K17972 N-terminal acetyltransferase B complex catalytic subunit [EC:2.3.1.88] (A)"	--	[R]	General function prediction only	Acetyltransferase (GNAT) family;; FR47-like protein;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain	N-alpha-acetyltransferase 20 GN=NAA20 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: N-alpha-acetyltransferase 20 [Camelus bactrianus] 
ENSG00000173421(CCDC36)	--	0.020234066	1	0.137895408	8	0	0	0.034934033	2	0	0	0.02005626	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: DNA recombination (GO:0006310);; Biological Process: meiotic DNA double-strand break formation (GO:0042138);; 	--	--	--	--	--	Coiled-coil domain-containing protein 36 GN=CCDC36 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 36 [Equus caballus] 
ENSG00000173432(SAA1)	--	0.780570028	5	0.503871661	3	1.173791834	7	2.625525035	18	3.032663882	19	6.488155784	43	--	--	--	--	--	--	0.000435131	2.379170822	up	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; 	"K17310|1.52726e-84|hsa:6288|SAA1, PIG4, SAA, SAA2, TP53I4; serum amyloid A1; K17310 serum amyloid A protein (A)"	--	--	--	Serum amyloid A protein	Serum amyloid protein A(4-101) (Precursor) GN=SAA1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: serum amyloid A-1 protein-like [Trichechus manatus latirostris]
ENSG00000173442(EHBP1L1)	--	32.3775136	2776	23.4841338	2429	25.46789837	2710	34.92551038	3187	34.6741684	2981	25.66434182	2325	0.982624375	0.16827222	normal	0.954193029	0.273853194	normal	0.96851815	-0.229215336	normal	0.775551266	0.079709773	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Protein of unknown function (DUF3585);; N-terminal C2 in EEIG1 and EHBP1 proteins;; Calponin homology (CH) domain;; CAMSAP CH domain	EH domain-binding protein 1-like protein 1 GN=EHBP1L1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: EH domain-binding protein 1-like protein 1 [Pteropus alecto] 
ENSG00000173451(THAP2)	--	3.671740814	169	4.555790599	220	5.644790081	244	3.721619044	240	4.196471261	217	3.253101395	202	0.695707858	0.471565408	normal	0.965190237	-0.040951595	normal	0.920064226	-0.278914426	normal	0.946734065	0.036719814	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 2 GN=THAP2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: THAP domain-containing protein 2 [Myotis davidii]
ENSG00000173456(RNF26)	--	28.6059	1302	27.1447	1249	29.1499	1347	23.5586	1072	26.8583	1214	25.0874	1146	0.896205461	-0.310851771	normal	0.980156264	-0.062355029	normal	0.948112733	-0.241140394	normal	0.273071578	-0.204518755	normal	--	--	--	K15693|0|hsa:79102|RNF26; ring finger protein 26; K15693 RING finger protein 26 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger)"	RING finger protein 26 GN=RNF26 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 26 [Galeopterus variegatus]
ENSG00000173457(PPP1R14B)	--	146.19956	2337	154.499281	2642	151.205586	2611	208.43295	3497	191.474973	3085	175.452645	2839	0.176538442	0.550330236	normal	0.976958411	0.202106322	normal	0.986467853	0.112426486	normal	0.077271738	0.290002859	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of phosphorylation (GO:0042325);; 	K17555|3.11328e-64|ptr:741983|PPP1R14B; protein phosphatase 1 regulatory subunit 14B; K17555 protein phosphatase 1 regulatory subunit 14B (A)	--	--	--	PKC-activated protein phosphatase-1 inhibitor	Protein phosphatase 1 regulatory subunit 14B GN=PPP1R14B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: protein phosphatase 1 regulatory subunit 14B, partial [Eptesicus fuscus]"
ENSG00000173465(SSSCA1)	--	49.8214902	883	45.78701199	777	59.32746617	957	63.72675348	1059	58.61382958	1096	57.436752	967	0.94665944	0.231017546	normal	0.46488274	0.47405439	normal	0.979154302	0.006694998	normal	0.215214677	0.233427673	normal	--	--	--	--	--	[DV]	"Cell cycle control, cell division, chromosome partitioning;; Defense mechanisms"	Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27)	Sjoegren syndrome/scleroderma autoantigen 1 GN=SSSCA1 OS=Homo sapiens (Human) PE=1 SV=1	DV	"Cell cycle control, cell division, chromosome partitioning;; Defense mechanisms"	PREDICTED: Sjoegren syndrome/scleroderma autoantigen 1 [Camelus ferus] 
ENSG00000173473(SMARCC1)	--	15.50069604	2087	16.21058361	2184	16.18712141	2161	20.44389707	2746	20.02328166	2672	17.66036272	2373	0.855626189	0.364833992	normal	0.953240678	0.269351733	normal	0.9835168	0.126636989	normal	0.13338175	0.254950971	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	"K11649|0|hsa:6599|SMARCC1, BAF155, CRACC1, Rsc8, SRG3, SWI3; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1; K11649 SWI/SNF related-matrix-associated actin-dependent regulator of chromatin subfamily C (A)"	--	[B]	Chromatin structure and dynamics	SWIRM domain;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain	SWI/SNF complex subunit SMARCC1 GN=SMARCC1 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: SWI/SNF complex subunit SMARCC1 [Ceratotherium simum simum]
ENSG00000173480(ZNF417)	--	5.132692169	280	5.637630573	291	6.154040461	278	3.837813957	234	4.892544	255	4.809637	270	0.910917742	-0.288018923	normal	0.942079545	-0.210777303	normal	0.966432478	-0.050140137	normal	0.574773832	-0.182464209	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:147687|ZNF417; zinc finger protein 417; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 417 GN=ZNF417 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 256-like isoform X1 [Galeopterus variegatus]
ENSG00000173482(PTPRM)	--	23.42227152	2585	22.12373078	2408	24.14334195	2449	18.96634197	2037	21.92638811	2207	22.13866063	2089	0.833957242	-0.374299252	normal	0.981560246	-0.147078797	normal	0.963755896	-0.237512742	normal	0.135807808	-0.253895959	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Molecular Function: protein binding (GO:0005515);; Biological Process: protein dephosphorylation (GO:0006470);; Cellular Component: membrane (GO:0016020);; 	"K05693|0|hsa:5797|PTPRM, PTPRL1, R-PTP-MU, RPTPM, RPTPU, hR-PTPu; protein tyrosine phosphatase, receptor type, M (EC:3.1.3.48); K05693 receptor-type tyrosine-protein phosphatase mu [EC:3.1.3.48] (A)"	Cell adhesion molecules (CAMs) (ko04514);; Adherens junction (ko04520)	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; MAM domain;; Fibronectin type III domain;; Dual specificity phosphatase, catalytic domain;; Immunoglobulin domain;; Tyrosine phosphatase family"	Receptor-type tyrosine-protein phosphatase mu (Precursor) GN=PTPRM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: receptor-type tyrosine-protein phosphatase mu isoform X1 [Felis catus]
ENSG00000173486(FKBP2)	--	65.4925	702	67.91919855	769	67.66471715	785	65.29806785	729	62.6157254	644	66.42065411	734	0.975413866	0.02356491	normal	0.91482761	-0.276753838	normal	0.971550353	-0.104994808	normal	0.626557214	-0.119702472	normal	--	--	--	"K09569|4.94312e-99|hsa:2286|FKBP2, FKBP-13, PPIase; FK506 binding protein 2, 13kDa (EC:5.2.1.8); K09569 FK506-binding protein 2 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase	Peptidyl-prolyl cis-trans isomerase FKBP2 (Precursor) GN=FKBP2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase FKBP2 isoform X2 [Tupaia chinensis] 
ENSG00000173511(VEGFB)	--	54.628112	973	64.03110902	1172	56.38266101	1051	56.08719184	1022	48.70643044	877	72.64241049	1353	0.978917725	0.039989608	normal	0.603125233	-0.439092887	normal	0.832860679	0.355655548	normal	0.997953243	0.004590189	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	K16858|7.82631e-101|mcf:102127655|VEGFB; vascular endothelial growth factor B; K16858 vascular endothelial growth factor B (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Pathways in cancer (ko05200)	--	--	PDGF/VEGF domain	Vascular endothelial growth factor B (Precursor) GN=VEGFB OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	vascular endothelial growth factor B186 precursor [Bos taurus]
ENSG00000173517(PEAK1)	--	7.329357163	1311	6.8984733	1307	9.75546132	1322	9.30503176	1796	8.231006469	1561	8.78612533	1368	0.665268281	0.422862488	normal	0.954347405	0.234536255	normal	0.982378754	0.041008494	normal	0.170103012	0.240115278	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17538|0|hsa:79834|PEAK1, SGK269; pseudopodium-enriched atypical kinase 1 (EC:2.7.10.2); K17538 pseudopodium-enriched atypical kinase 1 [EC:2.7.10.2] (A)"	--	--	--	Protein kinase domain;; Protein tyrosine kinase	Pseudopodium-enriched atypical kinase 1 GN=PEAK1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: pseudopodium-enriched atypical kinase 1-like [Ceratotherium simum simum]
ENSG00000173530(TNFRSF10D)	--	15.1683	883	14.8601	872	11.6672	678	20.8314	1217	23.2915	1350	23.9498	1397	0.615606725	0.431369846	normal	0.061175074	0.608278701	normal	2.44E-07	1.033043651	up	2.94E-06	0.683031129	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04722|0|hsa:8793|TNFRSF10D, CD264, DCR2, TRAIL-R4, TRAILR4, TRUNDD; tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain; K04722 tumor necrosis factor receptor superfamily member 10 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; Measles (ko05162);; Influenza A (ko05164)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 10D (Precursor) GN=UNQ251/PRO288 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 10A isoform X1 [Physeter catodon]
ENSG00000173531(MST1)	--	0.59205547	23	0.423378	21	0.899322	27	0.49137	24	0.880388	42	1.0513094	49	0.987649173	0.02869199	normal	0.784176492	0.930375699	normal	0.812419798	0.817103139	normal	0.292092001	0.677016909	normal	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	--	--	Kringle domain;; Trypsin;; PAN domain	Hepatocyte growth factor-like protein beta chain (Precursor) GN=MST1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: hepatocyte growth factor-like protein isoform X1 [Felis catus]
ENSG00000173535(TNFRSF10C)	--	3.542588163	116	3.399970368	113	3.116635615	91	5.626010544	261	5.759864	256	4.146189053	235	4.43E-05	1.128868789	up	3.97E-05	1.147916686	up	8.89E-07	1.346001062	up	2.09E-06	1.210786793	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K04722|2.71587e-132|hsa:8794|TNFRSF10C, CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain; K04722 tumor necrosis factor receptor superfamily member 10 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Apoptosis (ko04210);; Natural killer cell mediated cytotoxicity (ko04650);; Measles (ko05162);; Influenza A (ko05164)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 10C (Precursor) GN=UNQ321/PRO366 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 10A isoform X1 [Physeter catodon]
ENSG00000173540(GMPPB)	--	13.89895639	695	13.01462	721	14.56342	734	15.53434	770	15.9002242	816	14.63273	805	0.969647188	0.116767899	normal	0.96380911	0.156833975	normal	0.969448825	0.124671925	normal	0.578504254	0.132302185	normal	[MJ]	"Cell wall/membrane/envelope biogenesis;; Translation, ribosomal structure and biogenesis"	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; 	"K00966|0|hsa:29925|GMPPB, MDDGA14, MDDGB14, MDDGC14; GDP-mannose pyrophosphorylase B (EC:2.7.7.13); K00966 mannose-1-phosphate guanylyltransferase [EC:2.7.7.13] (A)"	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[M]	Cell wall/membrane/envelope biogenesis	Nucleotidyl transferase;; MobA-like NTP transferase domain;; Bacterial transferase hexapeptide (six repeats)	Mannose-1-phosphate guanyltransferase beta GN=GMPPB OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: mannose-1-phosphate guanyltransferase beta isoform X1 [Vicugna pacos]
ENSG00000173542(MOB1B)	--	8.863749657	731	9.313800651	816	8.257984137	704	7.36683322	688	7.91446567	689	6.43530037	594	0.969096403	-0.118039307	normal	0.924005737	-0.264956604	normal	0.928598388	-0.252811961	normal	0.313164772	-0.213413239	normal	--	--	--	"K06685|2.61916e-166|ptr:741698|MOB1B, MOBKL1A; MOB kinase activator 1B; K06685 MOB kinase activator 1 (A)"	Hippo signaling pathway (ko04390)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mob1/phocein family	MOB kinase activator 1B GN=MOB1B OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: MOB kinase activator 1B [Odobenus rosmarus divergens]
ENSG00000173545(ZNF622)	--	20.8057	707	19.7499	692	19.685	688	26.6596	923	23.8326	802	24.6083	838	0.824707593	0.353114896	normal	0.95555044	0.191015608	normal	0.916483219	0.275700298	normal	0.148021261	0.274843475	normal	--	--	--	"K14816|0|hsa:90441|ZNF622, ZPR9; zinc finger protein 622; K14816 pre-60S factor REI1 (A)"	--	[R]	General function prediction only	C2H2 type zinc-finger (2 copies);; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type	Zinc finger protein 622 GN=ZNF622 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 622 [Tupaia chinensis] 
ENSG00000173546(CSPG4)	--	0.358318	62	0.309979	55	0.275829	49	0.174083	30	0.264238	45	0.177325	31	0.310104448	-1.040272094	normal	0.965834134	-0.301744241	normal	0.909293622	-0.643623791	normal	0.220464286	-0.668293527	normal	--	--	--	"K08115|0|hsa:1464|CSPG4, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2; chondroitin sulfate proteoglycan 4; K08115 chondroitin sulfate proteoglycan 4 (A)"	--	[R]	General function prediction only	Laminin G domain;; Laminin G domain	Chondroitin sulfate proteoglycan 4 (Precursor) GN=CSPG4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: chondroitin sulfate proteoglycan 4 [Galeopterus variegatus]
ENSG00000173548(SNX33)	--	11.33296	1375	11.53212	1496	11.65671	1479	10.49565	1308	8.93714	1168	8.96544	1216	0.979106771	-0.102783564	normal	0.798560926	-0.378062707	normal	0.920193541	-0.290442189	normal	0.137802509	-0.258027702	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	"K17923|0|hsa:257364|SNX33, SH3PX3, SH3PXD3C, SNX30; sorting nexin 33; K17923 sorting nexin-9/18/33 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	WASP-binding domain of Sorting nexin protein;; PX domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Sorting nexin-33 GN=SNX33 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-33 [Ceratotherium simum simum]
ENSG00000173557(C2orf70)	--	0.402946156	16	0.418808298	12	0.177681031	5	0.191303897	4	0.073577391	2	0.0497182	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF2475)	UPF0573 protein C2orf70 GN=C2orf70 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0573 protein C2orf70 homolog [Galeopterus variegatus]
ENSG00000173559(NABP1)	--	15.03467473	1137	16.890492	1140	17.15719909	1096	14.69822969	1432	15.028629	1177	17.117918	1405	0.908404532	0.301603163	normal	0.98058954	0.024621794	normal	0.845386654	0.349603792	normal	0.204732315	0.229604025	normal	[L]	"Replication, recombination and repair"	--	--	--	[R]	General function prediction only	OB-fold nucleic acid binding domain	SOSS complex subunit B2 GN=NABP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SOSS complex subunit B2 isoform 1 [Ceratotherium simum simum]
ENSG00000173567(ADGRF3)	--	0.01619084	1	0.119692	9	0.039208	2	0.016298812	1	0.085724	5	0.0802242	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08456|0|hsa:165082|GPR113, PGR23, hGPCR37, ADGRF3; G protein-coupled receptor 113; K08456 G protein-coupled receptor 113 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Domain of unknown function (DUF3497);; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain	Probable G-protein coupled receptor 113 (Precursor) GN=GPR113 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 113 [Tupaia chinensis]
ENSG00000173575(CHD2)	--	43.59990837	2465	52.40570851	2898	43.43623184	2680	52.89516204	2730	51.96608985	2509	74.09876467	3747	0.985732862	0.116412076	normal	0.97005048	-0.229242983	normal	0.516581117	0.474983835	normal	0.723241561	0.139641808	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K11367|0|ptr:101057134|CHD2; chromodomain helicase DNA binding protein 2; K11367 chromodomain-helicase-DNA-binding protein 1 [EC:3.6.4.12] (A)	--	[K]	Transcription	SNF2 family N-terminal domain;; Domain of unknown function (DUF4208);; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain	Chromodomain-helicase-DNA-binding protein 2 GN=CHD2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: chromodomain-helicase-DNA-binding protein 2 isoform 1 [Dasypus novemcinctus]
ENSG00000173585(CCR9)	--	0	0	0	0	0	0	0	0	0.023891362	0	0.02440541	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04184|0|nle:100606852|CCR9; chemokine (C-C motif) receptor 9; K04184 C-C chemokine receptor type 9 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Intestinal immune network for IgA production (ko04672)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	C-C chemokine receptor type 9 GN=CCR9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C-C chemokine receptor type 9 [Galeopterus variegatus]
ENSG00000173588(CEP83)	--	3.817416554	216	4.257177423	279	4.411971304	298	4.54999999	280	3.986071253	248	3.1950347	219	0.872053987	0.341425265	normal	0.947680682	-0.190256972	normal	0.691986393	-0.449998219	normal	0.779278377	-0.107857023	normal	--	--	--	"K16754|0|hsa:51134|CEP83, CCDC41, NPHP18, NY-REN-58; centrosomal protein 83kDa; K16754 coiled-coil domain-containing protein 41 (A)"	--	--	--	--	Centrosomal protein of 83 kDa GN=CEP83 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 41 [Ceratotherium simum simum]
ENSG00000173597(SULT1B1)	--	0.145631389	13	0.101286673	9	0.079389756	6	0.188847917	3	0.076007645	6	0.122691883	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K01025|0|hsa:27284|SULT1B1, ST1B1, ST1B2, SULT1B2; sulfotransferase family, cytosolic, 1B, member 1 (EC:2.8.2.-); K01025 [EC:2.8.2.-] (A)"	--	[R]	General function prediction only	Sulfotransferase domain	Sulfotransferase family cytosolic 1B member 1 GN=SULT1B1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sulfotransferase family cytosolic 1B member 1 isoform X1 [Panthera tigris altaica]
ENSG00000173598(NUDT4)	--	13.6673236	866	14.025208	906	15.046638	931	21.366417	1393	19.469139	1272	19.805446	1288	0.018741535	0.654001369	normal	0.492206056	0.467427813	normal	0.50546546	0.459351022	normal	0.000457025	0.527012558	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K07766|5.71194e-120|ptr:736394|NUDT4; nudix (nucleoside diphosphate linked moiety X)-type motif 4; K07766 diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] (A)	--	[T]	Signal transduction mechanisms	NUDIX domain	Diphosphoinositol polyphosphate phosphohydrolase 2 GN=NUDT4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: diphosphoinositol polyphosphate phosphohydrolase 2 isoform 1 [Tursiops truncatus] 
ENSG00000173599(PC)	--	9.955105925	827	7.277699583	636	7.486518417	649	5.777958288	479	6.961584717	548	8.39927929	644	0.000557936	-0.816673649	normal	0.935879885	-0.235673068	normal	0.974430463	-0.019403842	normal	0.161964824	-0.35834264	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; 	"K01958|0|hsa:5091|PC, PCB; pyruvate carboxylase (EC:6.4.1.1); K01958 pyruvate carboxylase [EC:6.4.1.1] (A)"	Citrate cycle (TCA cycle) (ko00020);; Pyruvate metabolism (ko00620);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[C]	Energy production and conversion	"Carbamoyl-phosphate synthase L chain, ATP binding domain;; Conserved carboxylase domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; HMGL-like;; Biotin-requiring enzyme;; ATP-grasp domain;; D-ala D-ala ligase C-terminus;; Biotin-lipoyl like"	"Pyruvate carboxylase, mitochondrial (Precursor) GN=PC OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: pyruvate carboxylase, mitochondrial isoform X2 [Vicugna pacos] "
ENSG00000173612(GPRC6A)	--	0.024950892	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04622|0|pps:100969940|GPRC6A; G protein-coupled receptor, class C, group 6, member A; K04622 G protein-coupled receptor family C group 6 member A (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	7 transmembrane sweet-taste receptor of 3 GCPR;; Receptor family ligand binding region;; Nine Cysteines Domain of family 3 GPCR	G-protein coupled receptor family C group 6 member A (Precursor) GN=GPRC6A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor family C group 6 member A isoform 1 [Odobenus rosmarus divergens]
ENSG00000173614(NMNAT1)	--	1.85290901	117	1.813610155	128	2.11697353	130	3.409944295	183	2.766208493	162	2.782182023	179	0.450624655	0.608070836	normal	0.918367994	0.31510769	normal	0.800181234	0.448690404	normal	0.170799444	0.461456438	normal	--	--	Molecular Function: catalytic activity (GO:0003824);; Biological Process: biosynthetic process (GO:0009058);; 	"K06210|0|hsa:64802|NMNAT1, LCA9, NMNAT, PNAT1; nicotinamide nucleotide adenylyltransferase 1 (EC:2.7.7.1 2.7.7.18); K06210 nicotinamide mononucleotide adenylyltransferase [EC:2.7.7.1 2.7.7.18] (A)"	Nicotinate and nicotinamide metabolism (ko00760)	[H]	Coenzyme transport and metabolism	Cytidylyltransferase	Nicotinamide mononucleotide adenylyltransferase 1 GN=NMNAT1 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: nicotinamide mononucleotide adenylyltransferase 1 [Trichechus manatus latirostris]
ENSG00000173621(LRFN4)	--	27.8068	1201	27.7149	1225	24.2435	1109	31.622	1401	26.790488	1168	30.1217	1358	0.965538796	0.191161956	normal	0.978225075	-0.090054163	normal	0.922764022	0.28358265	normal	0.54260568	0.130189798	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K16357|0|hsa:78999|LRFN4, FIGLER6, SALM3, SALM3.; leucine rich repeat and fibronectin type III domain containing 4; K16357 leucine-rich repeat and fibronectin type-III domain-containing protein 4 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Immunoglobulin I-set domain;; Leucine Rich repeat;; Fibronectin type III domain;; Immunoglobulin domain;; Leucine rich repeat	Leucine-rich repeat and fibronectin type-III domain-containing protein 4 (Precursor) GN=LRFN4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeat and fibronectin type-III domain-containing protein 4 [Vicugna pacos]
ENSG00000173626(TRAPPC3L)	--	0.077975714	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Transport protein particle (TRAPP) component	Trafficking protein particle complex subunit 3-like protein GN=TRAPPC3L OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 3-like protein [Sorex araneus]
ENSG00000173627(APOBEC4)	--	0	0	0	0	0	0	0	0	0	0	0.0233621	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	"K18773|0|hsa:403314|APOBEC4, C1orf169; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative); K18773 C->U-editing enzyme APOBEC4 [EC:3.5.4.-] (A)"	--	--	--	APOBEC-like N-terminal domain	Putative C-	A	RNA processing and modification	PREDICTED: putative C-
ENSG00000173638(SLC19A1)	--	15.42913229	705	13.99672582	597	18.45377849	737	18.25002394	767	15.58162583	718	12.2320594	520	0.972370865	0.090581769	normal	0.933296379	0.244261486	normal	0.327329551	-0.51019161	normal	0.910974783	-0.046258459	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K14609|0|pps:100980570|SLC19A1; folate transporter 1; K14609 solute carrier family 19 (folate transporter), member 1 (A)"	Vitamin digestion and absorption (ko04977)	[H]	Coenzyme transport and metabolism	Reduced folate carrier	Folate transporter 1 GN=SLC19A1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: folate transporter 1 [Ceratotherium simum simum]
ENSG00000173641(HSPB7)	--	0	0	0.08614912	5	0.033808339	1	0.025216796	1	0.01685228	0	0.07927345	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K09546|1.92704e-93|hsa:27129|HSPB7, cvHSP; heat shock 27kDa protein family, member 7 (cardiovascular); K09546 heat shock protein beta-7 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp20/alpha crystallin family	Heat shock protein beta-7 GN=HSPB7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein beta-7 [Condylura cristata]
ENSG00000173653(RCE1)	--	26.57419927	629	27.52666819	630	22.38473992	589	27.26386656	648	29.52849525	671	29.47618265	692	0.974284561	0.01207248	normal	0.971872525	0.06937301	normal	0.942492951	0.223682579	normal	0.707950128	0.100847049	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K08658|1.01137e-176|ggo:101125752|RCE1; CAAX prenyl protease 2; K08658 prenyl protein peptidase [EC:3.4.22.-] (A)	Terpenoid backbone biosynthesis (ko00900)	[O]	"Posttranslational modification, protein turnover, chaperones"	CAAX protease self-immunity	CAAX prenyl protease 2 GN=RCE1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: CAAX prenyl protease 2 isoform X4 [Canis lupus familiaris]
ENSG00000173660(UQCRH)	--	206.546	1545	215.338	1673	211.711	1655	228.441	1793	215.385	1602	226.303	1727	0.971600249	0.183766637	normal	0.98241226	-0.083912332	normal	0.984468488	0.053097924	normal	0.845389714	0.050582419	normal	--	--	--	"K00416|3.84294e-50|ptr:742376|UQCRH; cytochrome b-c1 complex subunit 6, mitochondrial; K00416 ubiquinol-cytochrome c reductase subunit 6 (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Ubiquinol-cytochrome C reductase hinge protein	"Cytochrome b-c1 complex subunit 6, mitochondrial (Precursor) GN=UQCRH OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: cytochrome b-c1 complex subunit 6, mitochondrial [Oryctolagus cuniculus]"
ENSG00000173662(TAS1R1)	--	0	0	0	0	0.143429262	3	0.036572295	1	0	0	0.0816223	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04624|0|hsa:80835|TAS1R1, GPR70, T1R1, TR1; taste receptor, type 1, member 1; K04624 taste receptor type 1 member 1 (A)"	Taste transduction (ko04742)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Nine Cysteines Domain of family 3 GPCR;; Periplasmic binding protein	Taste receptor type 1 member 1 (Precursor) GN=TAS1R1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: taste receptor type 1 member 1 isoform X2 [Felis catus]
ENSG00000173673(HES3)	--	0.387416	3	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09088|3.93405e-92|hsa:390992|HES3, bHLHb43; hes family bHLH transcription factor 3; K09088 hairy and enhancer of split 3 (A)"	--	--	--	Helix-loop-helix DNA-binding domain	Transcription factor HES-3 GN=HES3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor HES-3 [Orcinus orca]
ENSG00000173674(EIF1AX)	--	50.18911001	3000	61.476393	3658	57.99180803	3476	69.849893	4210	57.06895	3360	53.945185	3292	0.611583372	0.457826712	normal	0.986544918	-0.143958277	normal	0.98959915	-0.086716415	normal	0.778109312	0.078109764	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	"K03236|7.18305e-66|cfa:611715|EIF1AX; eukaryotic translation initiation factor 1A, X-chromosomal-like; K03236 translation initiation factor 1A (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Translation initiation factor 1A / IF-1	"Eukaryotic translation initiation factor 1A, X-chromosomal GN=EIF1AX OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: eukaryotic translation initiation factor 1A, X-chromosomal isoform X1 [Canis lupus familiaris]"
ENSG00000173681(CXorf23)	--	2.84772593	270	4.097658094	339	3.551526057	318	3.389057161	302	3.566723708	333	2.9419981	305	0.959706953	0.13005688	normal	0.966580119	-0.046978199	normal	0.966038228	-0.068177869	normal	1	-0.000985721	normal	--	--	--	--	--	--	--	THRAP3/BCLAF1 family	Uncharacterized protein CXorf23 GN=CXorf23 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein CXorf23 homolog isoform X2 [Sus scrofa] 
ENSG00000173692(PSMD1)	--	66.25776358	4267	71.50077426	4693	75.80559966	4897	59.85266204	3917	54.29459341	3519	46.9099757	3046	0.98746835	-0.154247251	normal	0.732750176	-0.436608411	normal	0.006581264	-0.692999726	normal	0.005558839	-0.424499844	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K03032|0|ptr:470674|PSMD1; proteasome (prosome, macropain) 26S subunit, non-ATPase, 1; K03032 26S proteasome regulatory subunit N2 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome/cyclosome repeat;; HEAT repeats;; HEAT repeat;; HEAT-like repeat	26S proteasome non-ATPase regulatory subunit 1 GN=PSMD1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 1 isoform X1 [Physeter catodon]
ENSG00000173698(ADGRG2)	--	6.836145933	558	6.873306756	555	6.244546363	506	2.632507084	217	2.659938642	216	5.626433693	464	7.62E-11	-1.38703962	down	2.08E-10	-1.376639591	down	0.96271061	-0.132889123	normal	0.018621943	-0.870958917	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08451|0|hsa:10149|GPR64, EDDM6, HE6, TM7LN2, ADGRG2; G protein-coupled receptor 64; K08451 G protein-coupled receptor 64 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Latrophilin/CL-1-like GPS domain	G-protein coupled receptor 64 (Precursor) GN=GPR64 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 64 [Equus caballus]
ENSG00000173702(MUC13)	--	3.11861564	170	2.873565547	157	3.2504304	178	4.5660888	236	5.417568978	287	6.5390904	316	0.763375616	0.439039206	normal	0.008269293	0.842769881	normal	0.008669831	0.814493051	normal	0.003840842	0.712266575	normal	--	--	--	"K17298|0|hsa:56667|MUC13, DRCC1, MUC-13; mucin 13, cell surface associated; K17298 mucin-13 (A)"	--	--	--	SEA domain	Mucin-13 (Precursor) GN=MUC13 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mucin-13 isoform X1 [Bubalus bubalis]
ENSG00000173705(SUSD5)	--	0.553560152	53	0.522592863	51	0.490531355	47	0.605405935	58	0.529436494	50	0.530929644	51	0.976785491	0.096552232	normal	0.977329236	-0.048541956	normal	0.977922379	0.106262017	normal	0.962333677	0.052678334	normal	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	--	--	--	--	Extracellular link domain;; Sushi domain (SCR repeat)	Sushi domain-containing protein 5 (Precursor) GN=SUSD5 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: sushi domain-containing protein 5 [Ceratotherium simum simum]
ENSG00000173706(HEG1)	--	8.513319363	1628	9.47305905	1810	9.955071498	1894	10.79183	2016	8.7737995	1657	13.717321	2559	0.939271856	0.277327122	normal	0.977548554	-0.148712736	normal	0.686421583	0.425558987	normal	0.566716321	0.204636097	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	EGF-like domain;; Calcium-binding EGF domain	Protein HEG homolog 1 (Precursor) GN=HEG1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: protein HEG homolog 1, partial [Tupaia chinensis]"
ENSG00000173726(TOMM20)	--	88.6224	4382	88.9201	4461	81.9051	4012	109.041	5456	99.1437	4879	97.7356	4843	0.9646299	0.285332094	normal	0.990943469	0.10775684	normal	0.970087018	0.263197532	normal	0.233353616	0.217895757	normal	--	--	Cellular Component: mitochondrial outer membrane translocase complex (GO:0005742);; Biological Process: protein targeting (GO:0006605);; Biological Process: intracellular protein transport (GO:0006886);; 	K17770|5.89983e-83|ssc:100152814|TOMM20; translocase of outer mitochondrial membrane 20 homolog (yeast); K17770 mitochondrial import receptor subunit TOM20 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	MAS20 protein import receptor	Mitochondrial import receptor subunit TOM20 homolog GN=TOMM20 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	"Mitochondrial import receptor subunit TOM20-like protein, partial [Bos mutus]"
ENSG00000173744(AGFG1)	--	77.59644021	3489	86.619978	4047	74.72445425	3302	51.6147289	2383	49.20432466	2411	51.44995403	2502	0.096360986	-0.58055548	normal	0.000948931	-0.768271406	normal	0.76929969	-0.408334214	normal	3.01E-05	-0.592225667	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; 	"K15044|0|hsa:3267|AGFG1, HRB, RAB, RIP; ArfGAP with FG repeats 1; K15044 Arf-GAP domain and FG repeats-containing protein 1 (A)"	Influenza A (ko05164)	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf	Arf-GAP domain and FG repeat-containing protein 1 GN=AGFG1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: arf-GAP domain and FG repeat-containing protein 1 [Oryctolagus cuniculus]
ENSG00000173757(STAT5B)	--	14.93903033	1506	13.47728779	1376	15.94942664	1621	19.54784167	1963	17.31877743	1731	18.50094	1850	0.858683894	0.351191549	normal	0.910445698	0.309394951	normal	0.972639576	0.182190528	normal	0.095466886	0.278854897	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: signal transduction (GO:0007165);; "	"K11224|0|hsa:6777|STAT5B, STAT5; signal transducer and activator of transcription 5B; K11224 signal transducer and activator of transcription 5B (A)"	ErbB signaling pathway (ko04012);; Chemokine signaling pathway (ko04062);; Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917);; Hepatitis B (ko05161);; Measles (ko05162);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221)	[KT]	Transcription;; Signal transduction mechanisms	"STAT protein, DNA binding domain;; STAT protein, all-alpha domain;; STAT protein, protein interaction domain;; SH2 domain"	Signal transducer and activator of transcription 5B GN=STAT5B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: signal transducer and activator of transcription 5B [Ceratotherium simum simum]
ENSG00000173762(CD7)	--	0.047765334	1	0.372039135	5	0.285995446	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06457|5.64315e-122|hsa:924|CD7, GP40, LEU-9, TP41, Tp40; CD7 molecule; K06457 CD7 antigen (A)"	Hematopoietic cell lineage (ko04640)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	T-cell antigen CD7 (Precursor) GN=CD7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: T-cell antigen CD7 [Physeter catodon]
ENSG00000173786(CNP)	--	42.840048	2351	38.6803108	2254	44.7010442	2464	47.0058534	2610	49.9939991	2758	42.5206722	2356	0.985013523	0.119868636	normal	0.954041019	0.26954466	normal	0.987235205	-0.072908392	normal	0.624874209	0.106540457	normal	--	--	"Molecular Function: 2',3'-cyclic-nucleotide 3'-phosphodiesterase activity (GO:0004113);; Biological Process: cyclic nucleotide catabolic process (GO:0009214);; Cellular Component: membrane (GO:0016020);; "	"K01121|0|hsa:1267|CNP, CNP1; 2',3'-cyclic nucleotide 3' phosphodiesterase (EC:3.1.4.37); K01121 2',3'-cyclic-nucleotide 3'-phosphodiesterase [EC:3.1.4.37] (A)"	--	[L]	"Replication, recombination and repair"	"2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP or CNPase);; AAA domain;; AAA domain;; Zeta toxin"	"2',3'-cyclic-nucleotide 3'-phosphodiesterase (Precursor) GN=CNP OS=Homo sapiens (Human) PE=1 SV=2"	L	"Replication, recombination and repair"	"PREDICTED: 2',3'-cyclic-nucleotide 3'-phosphodiesterase [Vicugna pacos]"
ENSG00000173801(JUP)	--	109.5181663	6785	90.10450253	5830	97.66306311	6251	92.08899715	5874	105.361131	6636	110.120705	7018	0.982200984	-0.238779636	normal	0.990065692	0.165351221	normal	0.99109815	0.158645262	normal	0.923805752	0.029138277	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10056|0|pps:100974976|JUP; junction plakoglobin; K10056 junction plakoglobin (A)	Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Acute myeloid leukemia (ko05221);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT repeat;; V-ATPase subunit H;; Armadillo-like	Junction plakoglobin GN=JUP OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: junction plakoglobin isoform X1 [Camelus ferus] 
ENSG00000173805(HAP1)	--	1.589997043	132	0.882582401	75	1.238813102	99	0.850651024	59	0.701205406	59	0.779658914	64	0.001806657	-1.171620894	down	0.945690654	-0.359410404	normal	0.719122625	-0.625667811	normal	0.053417341	-0.770508134	normal	--	--	--	K04647|0|ptr:743382|HAP1; huntingtin-associated protein 1; K04647 huntingtin-associated protein 1 (A)	GABAergic synapse (ko04727);; Huntington's disease (ko05016)	[S]	Function unknown	HAP1 N-terminal conserved region	Huntingtin-associated protein 1 GN=HAP1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: huntingtin-associated protein 1 [Ceratotherium simum simum]
ENSG00000173809(TDRD12)	--	55.3418858	1367	48.04298132	1222	55.6586141	1319	51.85946173	1295	60.41547336	1464	43.59650216	1101	0.978504666	-0.108767781	normal	0.951025114	0.238974212	normal	0.932642422	-0.268583999	normal	0.890153671	-0.039315023	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	K18409|0|pps:100992985|TDRD12; putative ATP-dependent RNA helicase TDRD12; K18409 ATP-dependent RNA helicase TDRD12 [EC:3.6.4.13] (A)	--	--	--	Tudor domain;; DEAD/DEAH box helicase	Putative ATP-dependent RNA helicase TDRD12 GN=TDRD12 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: putative ATP-dependent RNA helicase TDRD12 [Pteropus alecto]
ENSG00000173812(EIF1)	--	535.38926	10081	597.353514	11195	550.7477833	9902	473.434091	9005	456.458515	8562	731.218305	13805	0.991449911	-0.19364159	normal	0.891971975	-0.408198083	normal	0.732914049	0.471046392	normal	0.985893701	-0.01111803	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	K03113|1.06034e-65|umr:103672555|EIF1; eukaryotic translation initiation factor 1; K03113 translation initiation factor 1 (A)	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Translation initiation factor SUI1	Eukaryotic translation initiation factor 1 GN=EIF1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	eukaryotic translation initiation factor 1 [Ursus thibetanus mupinensis] 
ENSG00000173818(ENDOV)	--	18.95773632	457	16.11624948	440	16.95567291	384	13.40810827	326	15.71255934	372	15.09964828	387	0.383802651	-0.516089212	normal	0.919151463	-0.262644371	normal	0.969497238	0.002924341	normal	0.289356656	-0.260485363	normal	[L]	"Replication, recombination and repair"	Molecular Function: endonuclease activity (GO:0004519);; Biological Process: DNA repair (GO:0006281);; 	--	--	[R]	General function prediction only	Endonuclease V	Endonuclease V GN=ENDOV OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: endonuclease V isoform X6 [Physeter catodon]
ENSG00000173821(RNF213)	--	46.61845006	16980	43.48225758	15937	47.475519	17533	37.420973	13361	45.4060151	15923	48.63614432	17503	0.948266789	-0.376602209	normal	0.997320177	-0.022692309	normal	0.997640304	-0.010761164	normal	0.595179408	-0.128976803	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	"ATPase family associated with various cellular activities (AAA);; Zinc finger, C3HC4 type (RING finger);; AAA domain (dynein-related subfamily)"	E3 ubiquitin-protein ligase RNF213 GN=RNF213 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF213 [Ceratotherium simum simum]
ENSG00000173825(TIGD3)	--	1.01757	35	0.7846	28	1.09856	39	0.749153	26	0.338663	11	0.660898	23	0.972115793	-0.437317442	normal	0.744164693	-1.257553241	normal	0.916014219	-0.73273533	normal	0.222795004	-0.787075765	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; CENP-B N-terminal DNA-binding domain;; Tc5 transposase DNA-binding domain;; Homeodomain-like domain;; Helix-turn-helix domain;; Helix-turn-helix	Tigger transposable element-derived protein 3 GN=TIGD3 OS=Homo sapiens (Human) PE=1 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: tigger transposable element-derived protein 3 [Equus przewalskii]
ENSG00000173838(MARCH10)	--	0.223343887	8	0.55265426	12	0.265607371	10	0.482320815	10	1.070375103	19	0.244016011	10	--	--	--	--	--	--	--	--	--	--	--	--	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10665|0|hsa:162333|MARCH10, MARCH-X, RNF190; membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase; K10665 E3 ubiquitin-protein ligase MARCH10 [EC:6.3.2.19] (A)"	--	[A]	RNA processing and modification	RING-variant domain	Probable E3 ubiquitin-protein ligase MARCH10 GN=MARCH10 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase MARCH10 [Ceratotherium simum simum]
ENSG00000173846(PLK3)	--	4.25668	188	5.88736	263	4.43906	201	5.93932	264	6.6169	294	10.68535	482	0.707418018	0.45581643	normal	0.957441092	0.138572892	normal	2.68E-08	1.247295586	up	0.23278135	0.653987849	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08862|0|hsa:1263|PLK3, CNK, FNK, PRK; polo-like kinase 3 (EC:2.7.11.21); K08862 polo-like kinase 3 [EC:2.7.11.21] (A)"	FoxO signaling pathway (ko04068);; Tuberculosis (ko05152)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; POLO box duplicated region;; Kinase-like	Serine/threonine-protein kinase PLK3 GN=PLK3 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase PLK3 [Chrysochloris asiatica]
ENSG00000173848(NET1)	--	16.379597	978	15.36193101	918	15.76135922	941	32.280538	1906	32.754536	1889	22.958941	1314	5.02E-06	0.930743854	normal	3.89E-07	1.018436097	up	0.448191978	0.472761367	normal	0.000791749	0.826509322	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; PH domain;; Pleckstrin homology domain	Neuroepithelial cell-transforming gene 1 protein GN=NET1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuroepithelial cell-transforming gene 1 protein isoform X1 [Galeopterus variegatus]
ENSG00000173852(DPY19L1)	--	60.24841276	3864	55.38170277	3647	50.95098515	3486	48.20419585	3319	46.49104234	3176	44.64558824	3057	0.969786645	-0.250071308	normal	0.976226399	-0.220827627	normal	0.979819855	-0.197655822	normal	0.207422968	-0.224792304	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Q-cell neuroblast polarisation	Probable C-mannosyltransferase DPY19L1 GN=DPY19L1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein dpy-19 homolog 1 [Odobenus rosmarus divergens]
ENSG00000173868(PHOSPHO1)	--	1.35876098	30	0.552476856	8	0.309912526	8	0.393412621	11	0.72006427	20	0.529301713	11	0.603241462	-1.359082232	normal	0.92514407	1.158327057	normal	--	--	--	--	--	--	--	--	Molecular Function: phosphatase activity (GO:0016791);; 	"K06124|0|hsa:162466|PHOSPHO1; phosphatase, orphan 1 (EC:3.1.3.75); K06124 phosphoethanolamine/phosphocholine phosphatase [EC:3.1.3.75] (A)"	Glycerophospholipid metabolism (ko00564)	[R]	General function prediction only	Putative Phosphatase;; haloacid dehalogenase-like hydrolase	Phosphoethanolamine/phosphocholine phosphatase GN=PHOSPHO1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: phosphoethanolamine/phosphocholine phosphatase isoform 1 [Odobenus rosmarus divergens]
ENSG00000173875(ZNF791)	--	2.924765112	308	3.475133958	353	3.461178	339	2.651447685	278	3.091285225	313	3.398910076	339	0.951394594	-0.177743889	normal	0.946533989	-0.194048595	normal	0.968550791	-0.008254618	normal	0.705814122	-0.125256302	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:163049|ZNF791; zinc finger protein 791; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Probable zinc-binding domain;; TFIIH C1-like domain"	Zinc finger protein 791 GN=ZNF791 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 791 [Galeopterus variegatus]
ENSG00000173889(PHC3)	--	12.0580284	1380	12.2766396	1696	11.1870422	1594	10.12734201	1712	12.23880821	1771	13.6169853	1848	0.932297386	0.279901952	normal	0.9846713	0.040965738	normal	0.967517271	0.204841043	normal	0.378024595	0.170052148	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11458|0|hsa:80012|PHC3, EDR3, HPH3; polyhomeotic homolog 3 (Drosophila); K11458 polyhomeotic-like protein 3 (A)"	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Polyhomeotic-like protein 3 GN=PHC3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: polyhomeotic-like protein 3 isoform X6 [Oryctolagus cuniculus]
ENSG00000173890(GPR160)	--	3.356001361	78	2.739001378	68	3.127482473	70	6.426585709	159	5.710175642	137	7.661676788	189	0.010539397	0.982825648	normal	0.025090638	0.973597503	normal	2.12E-06	1.405450118	up	0.000238653	1.146176478	up	--	--	--	"K08438|0|hsa:26996|GPR160, GPCR1, GPCR150; G protein-coupled receptor 160; K08438 G protein-coupled receptor 160 (A)"	--	--	--	--	Probable G-protein coupled receptor 160 GN=GPR160 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 160 [Leptonychotes weddellii]
ENSG00000173894(CBX2)	--	7.553373	676	6.5039961	609	7.453263	714	6.548202	620	7.800268	701	7.621236	634	0.962132542	-0.155218753	normal	0.956127196	0.181126168	normal	0.957551253	-0.179329337	normal	0.862951462	-0.052959128	normal	--	--	--	"K11451|0|hsa:84733|CBX2, CDCA6, M33, SRXY5; chromobox homolog 2; K11451 chromobox protein 2 (A)"	--	--	--	Chromo (CHRromatin Organisation MOdifier) domain	Chromobox protein homolog 2 GN=CBX2 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: chromobox protein homolog 2 [Tursiops truncatus]
ENSG00000173898(SPTBN2)	--	2.514918362	491	2.419609717	494	3.106086853	549	4.98997972	957	5.213955428	1013	4.160601415	808	1.84E-05	0.929843293	normal	1.81E-06	1.012415705	up	0.193255995	0.548005904	normal	7.78E-08	0.835338496	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K06115|0|hsa:6712|SPTBN2, GTRAP41, SCA5, SCAR14; spectrin, beta, non-erythrocytic 2; K06115 spectrin beta (A)"	--	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Pleckstrin homology domain;; PH domain;; CAMSAP CH domain	"Spectrin beta chain, non-erythrocytic 2 GN=SPTBN2 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: spectrin beta chain, non-erythrocytic 2 isoform X1 [Felis catus]"
ENSG00000173905(GOLIM4)	--	11.60915685	1140	12.85381281	1273	13.25438392	1306	12.40034717	1224	12.35097971	1213	11.32433968	1116	0.979609063	0.071644277	normal	0.978644936	-0.090968702	normal	0.950173917	-0.234814847	normal	0.715752894	-0.087201089	normal	--	--	--	--	--	--	--	--	Golgi integral membrane protein 4 GN=GOLIM4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi integral membrane protein 4 [Ceratotherium simum simum]
ENSG00000173914(RBM4B)	--	11.189964	333	10.410039	328	11.930011	371	10.979413	328	10.659389	326	10.868787	340	0.967124429	-0.052414945	normal	0.966977843	-0.030111153	normal	0.960137684	-0.133606781	normal	0.837358592	-0.074997378	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	K13187|0|mcf:101865670|RNA-binding motif protein 4B; K13187 RNA-binding protein 4 (A)	--	[AR]	RNA processing and modification;; General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Zinc knuckle;; Calcipressin"	RNA-binding protein 4B GN=RBM4B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein 4B [Ailuropoda melanoleuca] 
ENSG00000173915(USMG5)	--	381.2247068	755	368.634189	757	402.0794109	854	469.7723914	1080	397.6702148	801	425.972089	921	0.398600844	0.484821717	normal	0.974621612	0.05996592	normal	0.97400285	0.100502234	normal	0.288174473	0.222417573	normal	--	--	--	K18194|4.37924e-35|ptr:735405|USMG5; up-regulated during skeletal muscle growth 5 homolog (mouse); K18194 up-regulated during skeletal muscle growth protein 5 (A)	--	--	--	ATP synthase regulation	Up-regulated during skeletal muscle growth protein 5 GN=USMG5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: up-regulated during skeletal muscle growth protein 5 isoform 1 [Orcinus orca] 
ENSG00000173917(HOXB2)	--	0.80844293	17	1.045727673	22	0.880401	18	1.035799277	22	0.459525	9	0.662036	14	0.986675758	0.315983346	normal	0.893731276	-1.18053505	normal	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09302|1.81683e-155|hsa:3212|HOXB2, HOX2, HOX2H, Hox-2.8, K8; homeobox B2; K09302 homeobox protein HoxA/B2 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-B2 GN=HOXB2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: homeobox protein Hox-B2 [Loxodonta africana]
ENSG00000173918(C1QTNF1)	--	43.7304954	1954	26.38907614	1183	40.88749612	1784	50.43164326	2276	44.57728102	1975	62.01772708	2764	0.974551211	0.189099961	normal	0.004262992	0.717259075	normal	0.035459292	0.622923026	normal	0.1434328	0.491162402	normal	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	Complement C1q tumor necrosis factor-related protein 1 (Precursor) GN=C1QTNF1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	complement C1q tumor necrosis factor-related protein 1 precursor [Bos taurus] 
ENSG00000173926(MARCH3)	--	0.355975289	25	0.88144	41	1.252938629	51	0.525742171	29	0.573143613	20	0.654915891	42	0.98502969	0.173392783	normal	0.718966115	-1.00301135	normal	0.971195645	-0.27926014	normal	0.612274373	-0.381959784	normal	[A]	RNA processing and modification	Molecular Function: zinc ion binding (GO:0008270);; 	"K10658|0|hsa:115123|MARCH3, MARCH-III, RNF173; membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase (EC:6.3.2.19); K10658 E3 ubiquitin-protein ligase MARCH3 [EC:6.3.2.19] (A)"	--	[A]	RNA processing and modification	RING-variant domain	E3 ubiquitin-protein ligase MARCH3 GN=MARCH3 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MARCH3 [Orcinus orca] 
ENSG00000173928(SWSAP1)	--	1.4783	40	1.45432	40	1.60446	44	1.21241	33	1.17976	32	1.31091	36	0.976341389	-0.295834172	normal	0.972891635	-0.32940111	normal	0.9742931	-0.28687941	normal	0.670679714	-0.3167609	normal	--	--	--	--	--	--	--	NACHT domain	ATPase SWSAP1 GN=SWSAP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ATPase SWSAP1 isoform X2 [Sus scrofa]
ENSG00000173930(SLCO4C1)	--	0.64227	56	0.49492	43	0.47142	40	0.0341799	3	0.166518	14	0.511298	45	1.38E-09	-3.690040604	down	0.079892133	-1.540810535	normal	0.978720058	0.156067837	normal	0.161667388	-1.180280861	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14355|0|hsa:353189|SLCO4C1, OATP-H, OATP-M1, OATP4C1, OATPX, PRO2176, SLC21A20; solute carrier organic anion transporter family, member 4C1; K14355 solute carrier organic anion transporter family, member 4C (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain	Solute carrier organic anion transporter family member 4C1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 4C1 [Loxodonta africana]
ENSG00000173933(RBM4)	--	86.31238884	2512	99.6666344	3094	93.59251319	2864	115.881595	3611	102.8944929	3187	88.62442526	2721	0.425039973	0.492477245	normal	0.990193998	0.021289012	normal	0.988192096	-0.082141474	normal	0.544984325	0.146404875	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	K13187|0|mcc:713490|RBM4; RNA binding motif protein 4; K13187 RNA-binding protein 4 (A)	--	[AR]	RNA processing and modification;; General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Zinc knuckle;; Calcipressin"	RNA-binding protein 4 GN=RBM4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein 14 [Galeopterus variegatus]
ENSG00000173947(PIFO)	--	1.005309158	23	0.948250959	39	0.873387413	23	0.222361245	5	0.26047305	10	0.457363141	17	0.327762096	-1.934590025	normal	0.025933055	-1.834804758	normal	0.983349941	-0.412718949	normal	0.025744222	-1.427812366	normal	--	--	--	--	--	--	--	--	Protein pitchfork GN=PIFO OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein pitchfork [Galeopterus variegatus]
ENSG00000173950(XXYLT1)	--	8.961766737	442	9.693430887	470	9.712203092	473	9.054277356	471	7.689605408	397	9.989022518	498	0.96918122	0.060644205	normal	0.918386549	-0.264022701	normal	0.969591039	0.065809043	normal	0.908434478	-0.040974351	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl transferase family 8	Xyloside xylosyltransferase 1 GN=XXYLT1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	xyloside xylosyltransferase 1 [Bos taurus] 
ENSG00000173960(UBXN2A)	--	15.21821201	740	14.57550163	793	16.66771095	720	14.1965151	750	12.87436251	694	13.02541694	579	0.976061088	-0.011443339	normal	0.94849266	-0.2133764	normal	0.869185453	-0.321969312	normal	0.426227704	-0.177414433	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Y]	Nuclear structure	SEP domain;; UBX domain	UBX domain-containing protein 2A GN=UBXN2A OS=Homo sapiens (Human) PE=2 SV=1	Y	Nuclear structure	PREDICTED: UBX domain-containing protein 2A [Pantholops hodgsonii]
ENSG00000173988(LRRC63)	--	0.119208643	4	0	0	0.033950229	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 63 GN=LRRC63 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: leucine rich repeat containing 63 [Pteropus alecto]
ENSG00000173991(TCAP)	--	1.04932	32	1.073830007	45	1.208703	44	0.639268626	26	0.612400987	24	0.864998626	35	0.980298881	-0.313653046	normal	0.779070591	-0.88686286	normal	0.972080961	-0.325856016	normal	0.421912358	-0.529624324	normal	--	--	--	--	--	--	--	Telethonin protein	Telethonin GN=TCAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: telethonin [Felis catus]
ENSG00000173992(CCS)	--	15.410747	364	14.62273133	370	15.44163964	380	11.82145891	289	13.543999	321	13.110273	289	0.830349507	-0.361982015	normal	0.936559306	-0.225388513	normal	0.76177068	-0.401383765	normal	0.180114667	-0.330428372	normal	[P]	Inorganic ion transport and metabolism	Biological Process: superoxide metabolic process (GO:0006801);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; 	K04569|0|ptr:451348|CCS; copper chaperone for superoxide dismutase; K04569 copper chaperone for superoxide dismutase (A)	Amyotrophic lateral sclerosis (ALS) (ko05014)	[P]	Inorganic ion transport and metabolism	Copper/zinc superoxide dismutase (SODC);; Heavy-metal-associated domain	Copper chaperone for superoxide dismutase GN=CCS OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: copper chaperone for superoxide dismutase [Oryctolagus cuniculus]
ENSG00000174007(CEP19)	--	2.219908	85	2.65563	109	3.519965926	143	1.56167	64	1.787269	69	2.15648	88	0.919563565	-0.431207415	normal	0.582992033	-0.66931038	normal	0.346062002	-0.699212536	normal	0.110918233	-0.628250769	normal	--	--	--	"K16801|9.96879e-121|hsa:84984|CEP19, C3orf34, MOSPGF; centrosomal protein 19kDa; K16801 centrosomal protein CEP19 (A)"	--	--	--	CEP19-like protein	Centrosomal protein of 19 kDa GN=CEP19 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 19 kDa [Trichechus manatus latirostris]
ENSG00000174010(KLHL15)	--	4.84495285	437	5.609469575	504	4.991538275	438	4.813996963	434	4.127726269	372	5.028912701	453	0.969686333	-0.040627167	normal	0.582675195	-0.457941586	normal	0.970016828	0.040152414	normal	0.580102846	-0.152632318	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10452|0|hsa:80311|KLHL15, HEL-S-305; kelch-like family member 15; K10452 kelch-like protein 15 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Kelch motif;; Kelch motif"	Kelch-like protein 15 GN=KLHL15 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 15 [Galeopterus variegatus]
ENSG00000174013(FBXO45)	--	6.73988	445	5.600352918	389	6.883210128	471	6.92448	462	6.0307	419	5.84686	400	0.970550615	0.023176718	normal	0.965601128	0.08543347	normal	0.93007311	-0.243170266	normal	0.895327936	-0.048172419	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10319|0|bom:102264866|FBXO45; F-box protein 45; K10319 F-box protein 45 (A)	--	[R]	General function prediction only	SPRY domain;; F-box-like;; F-box domain	F-box/SPRY domain-containing protein 1 GN=FBXO45 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: F-box/SPRY domain-containing protein 1 [Bos mutus]
ENSG00000174015(SPERT)	--	0.447659006	2	0	0	0	0	0.034555497	1	0.033833889	0	0.034233012	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Chibby family	Spermatid-associated protein GN=SPERT OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: spermatid-associated protein [Condylura cristata]
ENSG00000174016(FAM46D)	--	0	0	0	0	0	0	0	0	0	0	0.02169736	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF1693)	Protein FAM46D GN=FAM46D OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM46D-like [Odobenus rosmarus divergens]
ENSG00000174021(GNG5)	--	97.03902	851	104.80667	940	89.028654	793	108.083511	970	93.74088	832	98.28719	906	0.966593402	0.157726499	normal	0.956778613	-0.197166368	normal	0.960054255	0.183571002	normal	0.874611439	0.045927354	normal	--	--	--	"K04542|7.99167e-42|rno:79218|Gng5; guanine nucleotide binding protein (G protein), gamma 5; K04542 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 (Precursor) GN=GNG5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5, partial [Bos mutus]"
ENSG00000174032(SLC25A30)	--	5.321157648	295	5.313171861	299	7.83912457	430	5.25278531	285	5.055005146	279	7.16637506	360	0.96483693	-0.080160498	normal	0.959927226	-0.120674903	normal	0.919182613	-0.263616527	normal	0.691086411	-0.168066909	normal	--	--	--	"K15106|0|hsa:253512|SLC25A30, KMCP1; solute carrier family 25, member 30; K15106 solute carrier family 25 (mitochondrial carrier), member 14/30 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Kidney mitochondrial carrier protein 1 GN=SLC25A30 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: kidney mitochondrial carrier protein 1 [Orycteropus afer afer]
ENSG00000174038(C9orf131)	--	0.29154446	12	0.499599429	18	0.224994324	4	0.097346447	7	0.134492825	9	0.178014079	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM75 family	Uncharacterized protein C9orf131 GN=C9orf131 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C9orf131 homolog [Ceratotherium simum simum]
ENSG00000174059(CD34)	--	0.072666526	4	0	0	0	0	0.01824443	1	0.045780513	1	0.046586396	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06474|0|hsa:947|CD34; CD34 molecule; K06474 CD34 antigen (A)	Cell adhesion molecules (CAMs) (ko04514);; Hematopoietic cell lineage (ko04640)	--	--	CD34/Podocalyxin family	Hematopoietic progenitor cell antigen CD34 (Precursor) GN=CD34 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: hematopoietic progenitor cell antigen CD34 isoform X1 [Physeter catodon]
ENSG00000174080(CTSF)	--	28.4779461	1057	29.4499943	1106	22.92406401	888	17.00503081	639	22.0725071	823	24.02590728	911	0.001853311	-0.755491257	normal	0.571931382	-0.447102085	normal	0.978078975	0.028551928	normal	0.096959704	-0.383024723	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K01373|0|hsa:8722|CTSF, CATSF, CLN13; cathepsin F (EC:3.4.22.41); K01373 cathepsin F [EC:3.4.22.41] (A)"	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Cathepsin propeptide inhibitor domain (I29);; Peptidase C1-like family	Cathepsin F (Precursor) GN=CTSF OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: cathepsin F [Ceratotherium simum simum]
ENSG00000174099(MSRB3)	--	15.69349557	982	16.75332078	1198	13.72751843	986	24.59278676	1483	18.75669478	1290	15.9495939	1109	0.124416245	0.56316985	normal	0.979030816	0.085212926	normal	0.968314457	0.161075303	normal	0.222832775	0.271849284	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: peptide-methionine (R)-S-oxide reductase activity (GO:0033743);; Biological Process: oxidation-reduction process (GO:0055114);; 	K07305|5.7347e-118|ptr:744605|MSRB3; methionine sulfoxide reductase B3; K07305 peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SelR domain	Methionine-R-sulfoxide reductase B3 (Precursor) GN=MSRB3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: methionine-R-sulfoxide reductase B3, mitochondrial-like [Tupaia chinensis] "
ENSG00000174106(LEMD3)	--	8.26704	640	9.30716	729	8.80729	683	10.7955	846	10.2025	790	10.1747	790	0.788432112	0.370976766	normal	0.971940892	0.094319296	normal	0.95272691	0.201260946	normal	0.281185526	0.220104171	normal	[R]	General function prediction only	Cellular Component: integral component of nuclear inner membrane (GO:0005639);; 	--	--	--	--	Man1-Src1p-C-terminal domain;; LEM domain	Inner nuclear membrane protein Man1 GN=LEMD3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	Inner nuclear membrane protein Man1 [Pteropus alecto]
ENSG00000174109(C16orf91)	--	11.2646	168	12.99	202	9.26623	144	12.9846	199	11.8896	177	13.3355	200	0.947355135	0.211694524	normal	0.945669964	-0.210348711	normal	0.757278107	0.461509581	normal	0.736046919	0.142603646	normal	--	--	--	--	--	--	--	CCSMST1 family	Protein CCSMST1 (Precursor) GN=CCSMST1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein CCSMST1 [Myotis davidii] 
ENSG00000174123(TLR10)	--	0.023933027	1	0.016861185	1	0.034816985	1	0.032955026	2	0.023141071	0	0.016981515	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K10171|0|hsa:81793|TLR10, CD290; toll-like receptor 10; K10171 toll-like receptor 10 (A)"	--	[T]	Signal transduction mechanisms	TIR domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; TIR domain;; Leucine rich repeat;; Leucine Rich repeat	Toll-like receptor 10 (Precursor) GN=TLR10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: toll-like receptor 10 [Galeopterus variegatus]
ENSG00000174125(TLR1)	--	5.68454491	417	7.355787844	518	5.05623267	413	5.6637103	512	5.360583411	437	6.160910878	524	0.918336463	0.264383841	normal	0.917579276	-0.265899028	normal	0.855124594	0.334045241	normal	0.71901827	0.10648072	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K05398|0|hsa:7096|TLR1, CD281, TIL, TIL._LPRS5, rsc786; toll-like receptor 1; K05398 toll-like receptor 1 (A)"	Toll-like receptor signaling pathway (ko04620);; Tuberculosis (ko05152)	[T]	Signal transduction mechanisms	TIR domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; TIR domain;; Leucine rich repeat	Toll-like receptor 1 (Precursor) GN=TLR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: toll-like receptor 1 [Ceratotherium simum simum]
ENSG00000174132(FAM174A)	--	10.7719	210	11.0055	219	13.3724	265	9.61616	190	10.8809	211	11.0433	215	0.953955565	-0.173883921	normal	0.963628151	-0.074589637	normal	0.900730497	-0.307992106	normal	0.586555815	-0.192414754	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1180)	Membrane protein FAM174A (Precursor) GN=FAM174A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: membrane protein FAM174A isoform X1 [Tupaia chinensis] 
ENSG00000174136(RGMB)	--	6.32692	452	5.774481557	420	4.858812313	352	8.33591	556	7.52124	508	7.861258	540	0.916926955	0.267110051	normal	0.92528962	0.252185926	normal	0.107097862	0.606971582	normal	0.075675262	0.368405393	normal	--	--	--	"K06847|0|hsa:285704|RGMB, DRAGON; repulsive guidance molecule family member b; K06847 RGM domain family (A)"	--	--	--	Repulsive guidance molecule (RGM) C-terminus;; Repulsive guidance molecule (RGM) N-terminus	RGM domain family member B (Precursor) GN=RGMB OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: RGM domain family member B [Lipotes vexillifer]
ENSG00000174137(FAM53A)	--	1.650569	54	2.758909959	46	1.397646348	41	0.858064965	29	1.18906429	39	0.945377912	16	0.673067911	-0.892532241	normal	0.973685557	-0.250626776	normal	0.360554879	-1.287298289	normal	0.176172227	-0.769851221	normal	--	--	--	--	--	--	--	Family of FAM53	Protein FAM53A GN=FAM53A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM53A isoform X8 [Tupaia chinensis] 
ENSG00000174151(CYB561D1)	--	3.509686365	244	3.01111596	249	3.6190412	248	4.429849809	336	3.9449145	283	4.246086033	273	0.721968337	0.428440423	normal	0.953526263	0.16230465	normal	0.959761753	0.129516386	normal	0.402534623	0.245708652	normal	--	--	--	--	--	--	--	Eukaryotic cytochrome b561	Cytochrome b561 domain-containing protein 1 GN=CYB561D1 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: cytochrome b561 domain-containing protein 1 [Galeopterus variegatus]
ENSG00000174165(ZDHHC24)	--	13.59547	797	10.81309	689	11.3792	716	9.31902	570	9.17669	564	11.24638	650	0.304401323	-0.513273891	normal	0.884501149	-0.309483161	normal	0.964399405	-0.147484231	normal	0.087236576	-0.32454586	normal	[R]	General function prediction only	--	"K18932|3.68759e-122|hsa:254359|ZDHHC24; zinc finger, DHHC-type containing 24 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC24 GN=ZDHHC24 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC24 [Felis catus]
ENSG00000174173(TRMT10C)	--	24.39451054	675	26.10871703	741	26.67518142	748	28.78045432	828	28.66053296	814	23.32638777	669	0.924311829	0.263368998	normal	0.970295135	0.113906842	normal	0.96069987	-0.168962086	normal	0.789634621	0.073123754	normal	--	--	--	"K17654|0|hsa:54931|TRMT10C, HNYA, MRPP1, RG9MTD1; tRNA methyltransferase 10 homolog C (S. cerevisiae); K17654 mitochondrial ribonuclease P protein 1 [EC:2.1.1.-] (A)"	--	[S]	Function unknown	tRNA (Guanine-1)-methyltransferase	Mitochondrial ribonuclease P protein 1 (Precursor) GN=TRMT10C OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: mitochondrial ribonuclease P protein 1 [Galeopterus variegatus] 
ENSG00000174177(CTU2)	--	10.59312947	331	9.022349	296	10.18910335	346	11.2405371	352	11.38017685	374	10.158571	323	0.967057329	0.057652433	normal	0.883952713	0.314581902	normal	0.963165087	-0.107044965	normal	0.806806495	0.087318916	normal	--	--	Molecular Function: tRNA binding (GO:0000049);; Biological Process: tRNA wobble uridine modification (GO:0002098);; Biological Process: tRNA thio-modification (GO:0034227);; 	"K14169|0|hsa:348180|CTU2, C16orf84, NCS2, UPF0432; cytosolic thiouridylase subunit 2 homolog (S. pombe); K14169 cytoplasmic tRNA 2-thiolation protein 2 (A)"	Sulfur relay system (ko04122)	--	--	Protein of unknown function (DUF2392)	Cytoplasmic tRNA 2-thiolation protein 2 {ECO:0000255|HAMAP-Rule:MF_03054} OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PANDA_001215 [Ailuropoda melanoleuca]
ENSG00000174206(C12orf66)	--	6.623331314	411	5.037171227	345	5.402974269	365	5.199828941	364	6.081415081	421	6.704073359	437	0.944424957	-0.20521636	normal	0.918092676	0.264745327	normal	0.92631743	0.250495663	normal	0.747209522	0.103820778	normal	--	--	--	--	--	--	--	Eukaryotic protein of unknown function (DUF2003)	UPF0536 protein C12orf66 GN=C12orf66 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: UPF0536 protein C12orf66 homolog isoform X1 [Loxodonta africana]
ENSG00000174225(ARL13A)	--	0	0	0.0579781	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K07961|2.57973e-178|hsa:392509|ARL13A, ARL13, dJ341D10.2; ADP-ribosylation factor-like 13A; K07961 ADP-ribosylation factor-like protein 13 (A)"	--	[UZ]	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Miro-like protein;; Ras family	ADP-ribosylation factor-like protein 13A GN=ARL13A OS=Homo sapiens (Human) PE=2 SV=2	UZ	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	PREDICTED: ADP-ribosylation factor-like protein 13A [Leptonychotes weddellii]
ENSG00000174227(PIGG)	--	12.856795	711	12.79619535	713	12.15373238	678	11.893775	642	11.93732027	652	14.337338	784	0.957832351	-0.177704163	normal	0.963322036	-0.150123551	normal	0.952733343	0.20085997	normal	0.904777782	-0.037256572	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; 	"K05310|0|hsa:54872|PIGG, GPI7, LAS21, PRO4405, RLGS1930; phosphatidylinositol glycan anchor biosynthesis, class G; K05310 ethanolaminephosphotransferase [EC:2.7.-.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[T]	Signal transduction mechanisms	Type I phosphodiesterase / nucleotide pyrophosphatase	GPI ethanolamine phosphate transferase 2 GN=PIGG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: GPI ethanolamine phosphate transferase 2 [Tupaia chinensis]
ENSG00000174231(PRPF8)	--	100.979521	15952	105.6334015	16141	106.99536	16720	91.451912	14209	91.97872	14249	101.571625	15902	0.99392992	-0.197744359	normal	0.993642356	-0.201275759	normal	0.997128286	-0.080650583	normal	0.491403142	-0.158796323	normal	[A]	RNA processing and modification	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: protein binding (GO:0005515);; Molecular Function: U6 snRNA binding (GO:0017070);; Molecular Function: U5 snRNA binding (GO:0030623);; "	K12856|0|tup:102493541|PRPF8; pre-mRNA processing factor 8; K12856 pre-mRNA-processing factor 8 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"PROCN (NUC071) domain;; PRP8 domain IV core;; U6-snRNA interacting domain of PrP8;; PRO8NT (NUC069), PrP8 N-terminal domain;; U5-snRNA binding site 2 of PrP8;; PROCT (NUC072) domain;; RNA recognition motif of the spliceosomal PrP8;; JAB1/Mov34/MPN/PAD-1 ubiquitin protease"	Pre-mRNA-processing-splicing factor 8 GN=PRPF8 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	Pre-mRNA-processing-splicing factor 8 [Myotis brandtii]
ENSG00000174233(ADCY6)	--	10.92330038	982	10.13512221	1103	9.96064611	1078	13.8092804	1457	13.4491399	1330	12.3415325	1323	0.193262468	0.53767906	normal	0.944470181	0.248256551	normal	0.919423349	0.286800662	normal	0.027319213	0.356375745	normal	[T]	Signal transduction mechanisms	Molecular Function: adenylate cyclase activity (GO:0004016);; Cellular Component: plasma membrane (GO:0005886);; Biological Process: cAMP biosynthetic process (GO:0006171);; Biological Process: cyclic nucleotide biosynthetic process (GO:0009190);; Molecular Function: phosphorus-oxygen lyase activity (GO:0016849);; Biological Process: intracellular signal transduction (GO:0035556);; 	K08046|0|ggo:101139873|ADCY6; adenylate cyclase type 6 isoform 1; K08046 adenylate cyclase 6 [EC:4.6.1.1] (A)	Purine metabolism (ko00230);; Rap1 signaling pathway (ko04015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; GABAergic synapse (ko04727);; Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Vasopressin-regulated water reabsorption (ko04962);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Bile secretion (ko04976);; Morphine addiction (ko05032);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Dilated cardiomyopathy (ko05414)	[C]	Energy production and conversion	Adenylate and Guanylate cyclase catalytic domain;; Domain of Unknown Function (DUF1053)	Adenylate cyclase type 6 GN=ADCY6 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: adenylate cyclase type 6 isoform X1 [Tupaia chinensis] 
ENSG00000174236(REP15)	--	0.297626	5	0.292862	5	0.6399	10	0.233574	4	0.290659	4	0.11789	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: receptor recycling (GO:0001881);; 	--	--	--	--	Rab15 effector	Rab15 effector protein GN=REP15 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: rab15 effector protein [Ceratotherium simum simum]
ENSG00000174238(PITPNA)	--	30.67239923	2241	29.14564248	2170	31.31379901	2247	38.4442659	2794	38.238066	2733	33.965385	2365	0.943799303	0.287180488	normal	0.927410529	0.311170256	normal	0.987090484	0.06550564	normal	0.203464088	0.223688376	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Phosphatidylinositol transfer protein	Phosphatidylinositol transfer protein alpha isoform GN=PITPNA OS=Homo sapiens (Human) PE=1 SV=2	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: phosphatidylinositol transfer protein alpha isoform [Ailuropoda melanoleuca] 
ENSG00000174243(DDX23)	--	34.48776448	2771	35.56044836	2884	36.2980874	2953	42.001862	3400	41.54502951	3323	35.42523203	2861	0.961301541	0.264163361	normal	0.981120038	0.182899165	normal	0.989389263	-0.053925243	normal	0.518351631	0.133349656	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	K12858|0|umr:103675446|DDX23; DEAD (Asp-Glu-Ala-Asp) box polypeptide 23; K12858 ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13] (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX23 GN=DDX23 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX23 [Tupaia chinensis] 
ENSG00000174276(ZNHIT2)	--	14.155884	249	10.741602	184	11.93130076	226	13.9089004	256	15.063229	264	11.53770038	211	0.967141089	0.009110365	normal	0.612637869	0.49598567	normal	0.962379807	-0.106632587	normal	0.737561593	0.128045801	normal	--	--	--	--	--	[S]	Function unknown	HIT zinc finger	Zinc finger HIT domain-containing protein 2 GN=ZNHIT2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger HIT domain-containing protein 2 [Galeopterus variegatus]
ENSG00000174279(EVX2)	--	0.0165971	1	0.0161793	1	0.0159096	0	0.0163353	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09320|0|hsa:344191|EVX2, EVX-2; even-skipped homeobox 2; K09320 homeobox even-skipped homolog protein (A)"	--	[K]	Transcription	Homeobox domain	Homeobox even-skipped homolog protein 2 GN=EVX2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox even-skipped homolog protein 2 [Odobenus rosmarus divergens]
ENSG00000174282(ZBTB4)	--	23.04908	2764	23.10668	2809	24.11619	2934	22.9728	2732	21.71802	2577	24.3045	2924	0.989089899	-0.047605778	normal	0.983557428	-0.145708712	normal	0.9900147	-0.013210181	normal	0.77952704	-0.068158795	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10491|0|hsa:57659|ZBTB4, KAISO-L1, ZNF903; zinc finger and BTB domain containing 4; K10491 zinc finger and BTB domain-containing protein 4 (A)"	--	--	--	"Zinc finger, C2H2 type;; BTB/POZ domain;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 4 GN=ZBTB4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 4 [Equus caballus]
ENSG00000174292(TNK1)	--	0.364725	22	0.325297247	20	0.52494259	32	0.944818991	57	1.05111397	63	1.03033764	63	0.107212554	1.285016425	normal	0.006002719	1.563990783	up	0.485969867	0.936876615	normal	0.007318853	1.286202206	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08885|0|hsa:8711|TNK1; tyrosine kinase, non-receptor, 1 (EC:2.7.10.2); K08885 non-receptor tyrosine-protein kinase TNK1 [EC:2.7.10.2] (A)"	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain	Non-receptor tyrosine-protein kinase TNK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: non-receptor tyrosine-protein kinase TNK1 isoform X1 [Equus caballus]
ENSG00000174306(ZHX3)	--	4.07260933	532	2.837089557	378	2.7646199	561	5.277815429	801	4.53796115	706	3.319721906	523	0.166468681	0.5582217	normal	0.000232995	0.877247634	normal	0.967008997	-0.109176384	normal	0.197709848	0.442727299	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	"Homeobox domain;; Homeodomain leucine-zipper encoding, Homez;; Homeobox KN domain"	Zinc fingers and homeoboxes protein 3 GN=ZHX3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc fingers and homeoboxes protein 3 [Ceratotherium simum simum]
ENSG00000174307(PHLDA3)	--	69.52111447	2364	86.64009303	3092	81.51957776	2909	85.72747596	2989	89.70550312	2946	118.447054	4111	0.931920931	0.307422576	normal	0.9882232	-0.091163761	normal	0.452290107	0.490459117	normal	0.484710361	0.243994247	normal	--	--	--	--	--	--	--	--	Pleckstrin homology-like domain family A member 3 GN=PHLDA3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology-like domain family A member 3 [Condylura cristata]
ENSG00000174326(SLC16A11)	--	0.256297525	6	0.526880522	13	0.08111226	1	0.171228926	4	0.432134675	2	0.383597609	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08188|4.9552e-109|hsa:162515|SLC16A11, MCT11; solute carrier family 16, member 11; K08188 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 11 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; MFS_1 like family	Monocarboxylate transporter 11 GN=SLC16A11 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: monocarboxylate transporter 11 [Equus przewalskii]
ENSG00000174327(SLC16A13)	--	28.8387	948	32.3103	1080	33.7945	1138	14.64226	496	13.01234	428	23.8413	779	6.07E-06	-0.963180832	normal	5.26E-12	-1.353652599	down	0.153130523	-0.554201139	normal	0.000329578	-0.914244375	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K08189|0|hsa:201232|SLC16A13, MCT13; solute carrier family 16, member 13; K08189 MFS transporter, MCP family, solute carrier family 16 (monocarboxylic acid transporters), member 13 (A)"	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; Vacuole effluxer Atg22 like	Monocarboxylate transporter 13 GN=SLC16A13 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: monocarboxylate transporter 13 isoform X1 [Equus caballus] 
ENSG00000174332(GLIS1)	--	0.037127577	2	0	0	0.0356353	1	0.0186499	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09232|0|ptr:738808|GLIS1; GLIS family zinc finger 1; K09232 zinc finger protein GLIS1/3 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein GLIS1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein GLIS1 [Pteropus alecto] 
ENSG00000174343(CHRNA9)	--	0.227787055	10	0.173821289	7	0.049401316	1	0.706639669	33	0.977771782	43	0.350191	18	0.303322797	1.553825925	normal	0.000494693	2.367426404	up	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04810|0|hsa:55584|CHRNA9, HSA243342, NACHRA9; cholinergic receptor, nicotinic, alpha 9 (neuronal); K04810 nicotinic acetylcholine receptor alpha-9 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Neuronal acetylcholine receptor subunit alpha-9 (Precursor) GN=CHRNA9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuronal acetylcholine receptor subunit alpha-9 [Camelus ferus] 
ENSG00000174370(C11orf45)	--	2.2962008	148	2.669653491	156	3.701841633	149	2.850349915	134	1.626783852	104	3.06642595	149	0.958213344	-0.172315386	normal	0.546429289	-0.599223503	normal	0.967851441	-0.008208133	normal	0.554595163	-0.248198129	normal	--	--	--	--	--	--	--	--	Putative uncharacterized protein C11orf45 (Precursor) GN=C11orf45 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000174371(EXO1)	--	10.45319249	663	12.78732449	716	16.72680602	857	12.5375212	748	10.68393267	729	12.1407614	739	0.965454838	0.142885276	normal	0.975201704	0.004523201	normal	0.946928909	-0.221590781	normal	0.912431504	-0.033806566	normal	[L]	"Replication, recombination and repair"	Molecular Function: nuclease activity (GO:0004518);; Biological Process: DNA repair (GO:0006281);; 	K10746|0|pps:100993288|EXO1; exonuclease 1; K10746 exonuclease 1 [EC:3.1.-.-] (A)	Mismatch repair (ko03430)	[L]	"Replication, recombination and repair"	XPG I-region;; XPG N-terminal domain	Exonuclease 1 GN=EXO1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: exonuclease 1 [Balaenoptera acutorostrata scammoni]
ENSG00000174373(RALGAPA1)	--	4.310038074	665	5.820766013	808	4.828143849	711	4.61661956	647	4.334124691	688	4.784218015	711	0.972496146	-0.070256316	normal	0.931034634	-0.252859764	normal	0.975640759	-0.008273844	normal	0.64476993	-0.115161916	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	--	--	[T]	Signal transduction mechanisms	Rap/ran-GAP	Ral GTPase-activating protein subunit alpha-1 GN=RALGAPA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ral GTPase-activating protein subunit alpha-1 isoform X4 [Mustela putorius furo]
ENSG00000174405(LIG4)	--	5.554028867	377	4.5058297	301	5.863893454	385	5.276849918	362	5.148218074	348	5.836968369	399	0.965415209	-0.089036737	normal	0.948317292	0.187022783	normal	0.968809165	0.043072657	normal	0.919930835	0.040472622	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA ligase (ATP) activity (GO:0003910);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; 	"K10777|0|hsa:3981|LIG4, LIG4S; ligase IV, DNA, ATP-dependent (EC:6.5.1.1); K10777 DNA ligase 4 [EC:6.5.1.1] (A)"	Non-homologous end-joining (ko03450)	[L]	"Replication, recombination and repair"	"ATP dependent DNA ligase domain;; DNA ligase N terminus;; DNA ligase IV;; BRCA1 C Terminus (BRCT) domain;; ATP dependent DNA ligase C terminal region;; mRNA capping enzyme, catalytic domain"	DNA ligase 4 GN=LIG4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: DNA ligase 4 isoform X1 [Galeopterus variegatus]
ENSG00000174428(GTF2IRD2B)	--	1.534265868	80	3.041298479	110	2.431582583	72	2.52381098	83	1.717691749	101	3.128380933	143	0.973135364	0.021866779	normal	0.963771516	-0.142529069	normal	0.020888529	0.966972065	normal	0.595231857	0.299622181	normal	--	--	--	--	--	--	--	GTF2I-like repeat	General transcription factor II-I repeat domain-containing protein 2B GN=GTF2IRD2B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: general transcription factor II-I repeat domain-containing protein 2-like [Balaenoptera acutorostrata scammoni]
ENSG00000174429(ABRA)	--	0	0	0	0	0	0	0.0183518	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Costars	Actin-binding Rho-activating protein OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	Actin-binding Rho-activating protein [Tupaia chinensis]
ENSG00000174437(ATP2A2)	--	217.5480578	19120	241.168825	21661	212.400651	18593	217.774425	19646	206.4449898	18141	246.995795	22303	0.997863592	0.008320158	normal	0.989234229	-0.277251237	normal	0.991791735	0.25416787	normal	0.993528143	-0.003745555	normal	[P]	Inorganic ion transport and metabolism	--	"K05853|0|mcf:101867359|uncharacterized LOC101867359; K05853 Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 GN=ATP2A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	sarcoplasmic/endoplasmic reticulum calcium ATPase 2 [Sus scrofa] 
ENSG00000174442(ZWILCH)	--	27.49433	1324	24.1359504	1205	31.09288411	1550	25.94042432	1378	20.55465525	1065	22.73228137	1154	0.982697884	0.026810007	normal	0.960801923	-0.199339959	normal	0.617858427	-0.433424496	normal	0.389049031	-0.202866138	normal	--	--	Biological Process: mitotic cell cycle checkpoint (GO:0007093);; Cellular Component: RZZ complex (GO:1990423);; 	K11579|0|pon:100172715|ZWILCH; zwilch kinetochore protein; K11579 protein zwilch (A)	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2352)	Protein zwilch homolog GN=ZWILCH OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein zwilch homolog isoform X2 [Equus przewalskii]
ENSG00000174444(RPL4)	--	2165.349096	37683	1965.61089	33963	1936.4457	33832	2078.47431	37092	2180.514927	38139	1955.64037	34470	0.998706411	-0.053635824	normal	0.997916244	0.145870427	normal	0.998652304	0.018660565	normal	0.919370232	0.035183842	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02930|0|mcc:710590|RPL4; ribosomal protein L4; K02930 large subunit ribosomal protein L4e (A)	Ribosome (ko03010)	[A]	RNA processing and modification	Ribosomal protein L4/L1 family;; 60S ribosomal protein L4 C-terminal domain	60S ribosomal protein L4 GN=RPL4 OS=Homo sapiens (Human) PE=1 SV=5	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L4-like [Myotis lucifugus]
ENSG00000174446(SNAPC5)	--	38.63957	567	35.07080853	523	35.9357515	546	33.308861	489	33.467739	491	38.863915	569	0.930744847	-0.24363481	normal	0.965157432	-0.112179626	normal	0.97181566	0.051097614	normal	0.726284261	-0.099563232	normal	--	--	--	"K15211|7.9932e-37|ptr:100612370|SNAPC5; small nuclear RNA activating complex, polypeptide 5, 19kDa; K15211 snRNA-activating protein complex subunit 5 (A)"	--	--	--	"snRNA-activating protein complex subunit 19, SNAPc subunit 19"	snRNA-activating protein complex subunit 5 GN=SNAPC5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: snRNA-activating protein complex subunit 5 [Galeopterus variegatus]
ENSG00000174448(STARD6)	--	0	0	0.112594	1	0	0	0.113935	1	0	0	0.152228	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: lipid binding (GO:0008289);; 	--	--	[I]	Lipid transport and metabolism	START domain	StAR-related lipid transfer protein 6 GN=STARD6 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: stAR-related lipid transfer protein 6 isoform X1 [Oryctolagus cuniculus] 
ENSG00000174450(GOLGA6L2)	--	0.029264302	1	0	0	0	0	0	0	0.027698757	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	Golgin subfamily A member 6-like protein 2 GN=GOLGA6L2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: golgin subfamily A member 2-like [Oryctolagus cuniculus]
ENSG00000174453(VWC2L)	--	0	0	0	0	0	0	0	0	0	0	0.013417031	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	von Willebrand factor type C domain	von Willebrand factor C domain-containing protein 2-like (Precursor) GN=VWC2L OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: von Willebrand factor C domain-containing protein 2-like [Oryctolagus cuniculus]
ENSG00000174456(C12orf76)	--	8.505954199	189	10.4103933	237	10.7853668	228	7.557528277	166	6.537410371	153	10.44931	230	0.946803293	-0.216158553	normal	0.221536608	-0.64759579	normal	0.967031928	0.004280328	normal	0.416147999	-0.272646224	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C12orf76 GN=C12orf76 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein PANDA_022526 [Ailuropoda melanoleuca]
ENSG00000174460(ZCCHC12)	--	0.0480469	2	0.140368	6	0	0	0.0717711	3	0.0702659	2	0.0714413	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PNMA	Zinc finger CCHC domain-containing protein 12 GN=ZCCHC12 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger CCHC domain-containing protein 12 [Galeopterus variegatus]
ENSG00000174469(CNTNAP2)	--	0	0	0.009875105	1	0	0	0	0	0.009533928	0	0.00975015	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07380|0|hsa:26047|CNTNAP2, AUTS15, CASPR2, CDFE, NRXN4, PTHSL1; contactin associated protein-like 2; K07380 contactin associated protein-like 2 (A)"	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; F5/8 type C domain;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain	Contactin-associated protein-like 2 (Precursor) GN=CNTNAP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: contactin-associated protein-like 2 [Oryctolagus cuniculus]
ENSG00000174473(GALNTL6)	--	0.041654765	2	0.0402709	2	0.0597787	2	0.209546063	9	0.284996114	14	0.187920553	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K00710|0|hsa:442117|GALNTL6, GALNACT20, GALNT17, GalNAc-T6L; polypeptide N-acetylgalactosaminyltransferase-like 6 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase-like 6 GN=GALNTL6 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase-like 6 [Pteropus alecto]
ENSG00000174482(LINGO2)	--	0.834020998	12	0.612459967	9	0.059226977	2	1.178880391	18	2.42582836	39	0.954747671	28	--	--	--	0.017482232	1.926797938	normal	0.001414652	3.06453961	up	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine rich repeats (6 copies);; Leucine Rich repeats (2 copies);; Immunoglobulin I-set domain;; Leucine Rich Repeat;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 (Precursor) GN=LINGO2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2-like [Chrysochloris asiatica]
ENSG00000174483(BBS1)	--	33.76951882	1675	36.33592247	1751	42.42756194	1868	32.84608483	1597	36.52917658	1538	35.62815764	1838	0.98178502	-0.099535526	normal	0.965661879	-0.208357967	normal	0.985906102	-0.031623321	normal	0.60740737	-0.110887891	normal	--	--	--	"K16746|0|hsa:582|BBS1, BBS2L2; Bardet-Biedl syndrome 1; K16746 Bardet-Biedl syndrome 1 protein (A)"	--	--	--	Ciliary BBSome complex subunit 1	Bardet-Biedl syndrome 1 protein GN=BBS1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: Bardet-Biedl syndrome 1 protein isoform X1 [Felis catus]
ENSG00000174485(DENND4A)	--	6.85257881	878	5.53977	709	6.834861624	800	6.5325926	873	6.558258	820	5.497243671	717	0.977405046	-0.039003102	normal	0.956734168	0.18803852	normal	0.962341228	-0.165986703	normal	0.985893701	-0.007868771	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; dDENN domain;; uDENN domain;; PPR repeat family	C-myc promoter-binding protein GN=DENND4A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C-myc promoter-binding protein isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000174498(IGDCC3)	--	0.03696622	3	0	0	0.0104767	0	0.061796589	4	0.035934639	2	0.024395167	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Immunoglobulin superfamily DCC subclass member 3 (Precursor) GN=IGDCC3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	"PREDICTED: immunoglobulin superfamily DCC subclass member 3, partial [Physeter catodon]"
ENSG00000174500(GCSAM)	--	0.3991301	20	0.09095737	5	0.1812153	9	0.50383	28	0.56261	31	0.4121207	24	0.979676882	0.426785075	normal	0.014721583	2.301309915	normal	0.837534376	1.271666338	normal	0.050510626	1.265765304	normal	--	--	Biological Process: regulation of B cell receptor signaling pathway (GO:0050855);; Biological Process: regulation of lymphocyte migration (GO:2000401);; 	--	--	--	--	--	Germinal center-associated signaling and motility protein GN=GCSAM OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: germinal center-associated signaling and motility protein [Galeopterus variegatus]
ENSG00000174501(ANKRD36C)	--	4.356339277	987	4.301058999	1004	5.077851006	1039	3.562886354	736	3.10029183	660	3.7461038	662	0.528786023	-0.453355986	normal	0.048533978	-0.625476804	normal	0.020716467	-0.657374881	normal	0.000206619	-0.579543778	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 36C GN=ANKRD36C OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like [Physeter catodon]
ENSG00000174502(SLC26A9)	--	0.044574662	4	0.022331169	2	0.021970651	1	0.03342478	3	0.274556455	25	0.164526887	15	--	--	--	0.007848367	2.89998189	up	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14706|0|pps:100967362|SLC26A9; solute carrier family 26 (anion exchanger), member 9; K14706 solute carrier family 26 (sulfate anion transporter), member 9 (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain	Solute carrier family 26 member 9 GN=SLC26A9 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 26 member 9 [Felis catus]
ENSG00000174514(MFSD4A)	--	0.690342961	22	0.420961365	24	0.487691687	26	0.713550246	39	0.714248233	39	0.52911511	29	0.913490436	0.75508086	normal	0.936938332	0.646775708	normal	0.984838306	0.141456156	normal	0.427630066	0.549776508	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	--	--	Major Facilitator Superfamily	Major facilitator superfamily domain-containing protein 4 GN=MFSD4 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: major facilitator superfamily domain-containing protein 4 [Ailuropoda melanoleuca]
ENSG00000174516(PELI3)	--	5.735153712	273	6.150388654	259	5.382375836	261	4.553635404	215	4.716580632	215	4.714482029	204	0.83813247	-0.373024374	normal	0.912108664	-0.288192055	normal	0.856273492	-0.361397349	normal	0.228421152	-0.344191426	normal	--	--	Biological Process: Toll signaling pathway (GO:0008063);; 	K11964|0|cjc:100397435|PELI3; pellino E3 ubiquitin protein ligase family member 3; K11964 pellino (A)	--	[T]	Signal transduction mechanisms	Pellino	E3 ubiquitin-protein ligase pellino homolog 3 GN=PELI3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: E3 ubiquitin-protein ligase pellino homolog 3 [Galeopterus variegatus]
ENSG00000174521(TTC9B)	--	0.101952	1	0	0	0	0	0.0968297	1	0	0	0.0977035	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 9B GN=TTC9B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 9B [Camelus ferus] 
ENSG00000174527(MYO1H)	--	0.011634092	1	0	0	0	0	0.011594822	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	K10356|0|hsa:283446|MYO1H; myosin IH; K10356 myosin I (A)	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail	Unconventional myosin-Ih GN=MYO1H OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-Ih [Galeopterus variegatus]
ENSG00000174529(TMEM81)	--	1.43255	29	1.63609	34	1.67998	34	1.30649	27	2.21544	44	2.04699	42	0.985192786	-0.12695301	normal	0.970218147	0.337323445	normal	0.975563945	0.285133754	normal	0.822498071	0.200529175	normal	--	--	--	--	--	--	--	--	Transmembrane protein 81 (Precursor) GN=TMEM81 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 81 [Ceratotherium simum simum]
ENSG00000174547(MRPL11)	--	29.382284	697	34.682833	819	32.311956	761	38.51108	925	35.030906	830	35.718618	853	0.776353204	0.376739528	normal	0.976784577	-0.002174684	normal	0.965217606	0.156064768	normal	0.414747385	0.174311475	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02867|1.27014e-118|pps:100973378|MRPL11; mitochondrial ribosomal protein L11; K02867 large subunit ribosomal protein L11 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein L11, N-terminal domain;; Ribosomal protein L11, RNA binding domain"	"39S ribosomal protein L11, mitochondrial (Precursor) GN=MRPL11 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L11, mitochondrial isoform X1 [Ursus maritimus]"
ENSG00000174564(IL20RB)	--	0.4030614	13	0.074688814	3	0.292919201	8	0.5315667	21	0.458892	15	0.552098283	22	0.980308599	0.6044329	normal	--	--	--	0.862173971	1.298185009	normal	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05137|0|hsa:53833|IL20RB, DIRS1, FNDC6, IL-20R2; interleukin 20 receptor beta; K05137 interleukin 20 receptor beta (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	"Tissue factor;; Fibronectin type III domain;; Interferon-alpha/beta receptor, fibronectin type III"	Interleukin-20 receptor subunit beta (Precursor) GN=IL20RB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-20 receptor subunit beta [Leptonychotes weddellii]
ENSG00000174567(GOLT1A)	--	6.941726	64	6.05262701	62	3.408392623	35	7.164825779	69	5.249497983	53	12.18204908	126	0.974798085	0.075936344	normal	0.967420034	-0.241328533	normal	2.51E-07	1.796111729	up	0.487278674	0.603007021	normal	--	--	Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[P]	Inorganic ion transport and metabolism	Got1/Sft2-like family	Vesicle transport protein GOT1A OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle transport protein GOT1A isoform X1 [Tupaia chinensis]
ENSG00000174574(AKIRIN1)	--	29.89184153	1211	26.91675908	1143	27.7310524	1125	30.93594539	1211	34.03246605	1336	27.54922106	1108	0.981408059	-0.030793196	normal	0.961366433	0.203418904	normal	0.980551736	-0.030217631	normal	0.853759328	0.04975999	normal	--	--	--	--	--	[S]	Function unknown	--	Akirin-1 GN=AKIRIN1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: akirin-1 isoform X1 [Lipotes vexillifer]
ENSG00000174579(MSL2)	--	4.44149858	310	4.911443	328	5.045362057	334	4.723323048	340	5.276950863	379	5.262305103	378	0.963435055	0.10195169	normal	0.948744977	0.186275964	normal	0.953688533	0.169524757	normal	0.616984096	0.153766642	normal	--	--	Molecular Function: ubiquitin protein ligase activity (GO:0061630);; 	K13164|0|ptr:470933|MSL2; male-specific lethal 2 homolog (Drosophila); K13164 male-specific lethal 2 (A)	--	--	--	--	E3 ubiquitin-protein ligase MSL2 GN=MSL2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: E3 ubiquitin-protein ligase MSL2 isoform X1 [Oryctolagus cuniculus]
ENSG00000174586(ZNF497)	--	3.713075387	206	3.874715	200	3.321888	197	3.45959496	206	4.117341	200	4.91254711	264	0.966634814	-0.030604008	normal	0.965656897	-0.021265761	normal	0.790142774	0.41131407	normal	0.743716327	0.131486719	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain;; LYAR-type C2HC zinc finger;; LIM domain"	Zinc finger protein 497 GN=ZNF497 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 497 [Odobenus rosmarus divergens]
ENSG00000174599(TRAM1L1)	--	1.89233	53	2.29949	65	1.59196	44	1.92453	55	2.06942	58	0.881125	25	0.978152701	0.021981472	normal	0.970178129	-0.181344055	normal	0.866719351	-0.787512147	normal	0.720010787	-0.254852872	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TRAM1-like protein;; TLC domain	Translocating chain-associated membrane protein 1-like 1 GN=TRAM1L1 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: translocating chain-associated membrane protein 1-like 1 [Galeopterus variegatus]
ENSG00000174606(ANGEL2)	--	9.196291503	663	8.123687987	585	9.735375656	692	9.087125844	658	10.30532951	735	10.23038143	739	0.973993893	-0.041656648	normal	0.8875701	0.307171323	normal	0.972487494	0.086328295	normal	0.651480545	0.115553509	normal	[A]	RNA processing and modification	--	K18729|0|pps:100995614|ANGEL2; angel homolog 2 (Drosophila); K18729 protein angel (A)	--	[K]	Transcription	Endonuclease/Exonuclease/phosphatase family	Protein angel homolog 2 GN=ANGEL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein angel homolog 2 isoform X1 [Camelus ferus] 
ENSG00000174607(UGT8)	--	0.595104249	37	0.46572586	26	0.281022123	13	1.930556841	115	2.592988907	143	1.636333983	86	2.60E-05	1.566470669	up	2.92E-12	2.372318594	up	3.23E-09	2.584422841	up	1.06E-06	2.155349015	up	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K04628|0|hsa:7368|UGT8, CGT, UGT4; UDP glycosyltransferase 8 (EC:2.4.1.45); K04628 2-hydroxyacylsphingosine 1-beta-galactosyltransferase [EC:2.4.1.45] (A)"	Ether lipid metabolism (ko00565);; Sphingolipid metabolism (ko00600)	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain	2-hydroxyacylsphingosine 1-beta-galactosyltransferase (Precursor) GN=UGT8 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: 2-hydroxyacylsphingosine 1-beta-galactosyltransferase isoform 1 [Odobenus rosmarus divergens] 
ENSG00000174611(KY)	--	0	0	0	0	0	0	0	0	0.056007725	2	0.036781311	2	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	--	--	--	--	Transglutaminase-like superfamily	Kyphoscoliosis peptidase GN=KY OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: kyphoscoliosis peptidase isoform 1 [Equus caballus]
ENSG00000174628(IQCK)	--	3.944344	85	6.175047	98	6.8076	130	6.490757	124	4.701619	98	4.6670357	114	0.811283214	0.506356452	normal	0.969651726	-0.021100944	normal	0.957272656	-0.195340768	normal	0.898477272	0.081382198	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	--	IQ domain-containing protein K GN=IQCK OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: IQ domain-containing protein K [Capra hircus]
ENSG00000174652(ZNF266)	--	3.939015182	235	3.58963487	247	3.41384181	209	4.065935894	235	3.790215529	210	4.848640701	227	0.966666879	-0.030631993	normal	0.929200012	-0.253860475	normal	0.962055477	0.110133074	normal	0.894182217	-0.061824381	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; XPA protein N-terminal;; Probable zinc-binding domain;; Transposase zinc-ribbon domain"	Zinc finger protein 266 GN=ZNF266 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 266 [Galeopterus variegatus] 
ENSG00000174669(SLC29A2)	--	13.68168487	619	12.3288729	572	13.00160218	620	4.42311703	195	5.628933378	249	6.36055087	293	3.33E-16	-1.689392487	down	2.98E-08	-1.216276656	down	7.36E-07	-1.085715151	down	7.40E-14	-1.316917114	down	--	--	Molecular Function: nucleoside transmembrane transporter activity (GO:0005337);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15014|0|hsa:3177|SLC29A2, DER12, ENT2, HNP36; solute carrier family 29 (equilibrative nucleoside transporter), member 2; K15014 solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3 (A)"	--	[F]	Nucleotide transport and metabolism	Nucleoside transporter	Equilibrative nucleoside transporter 2 GN=SLC29A2 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: equilibrative nucleoside transporter 2 [Ailuropoda melanoleuca]
ENSG00000174672(BRSK2)	--	6.391993502	437	5.344075231	372	5.561337642	382	4.844720422	345	5.519764896	359	4.373741361	291	0.806241856	-0.37039953	normal	0.965781829	-0.072445514	normal	0.765907283	-0.399029233	normal	0.259647061	-0.281092636	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08796|0|nle:100589265|BRSK2; BR serine/threonine kinase 2; K08796 BR serine/threonine kinase [EC:2.7.11.1] (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Serine/threonine-protein kinase BRSK2 GN=BRSK2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase BRSK2 isoform 2 [Odobenus rosmarus divergens]
ENSG00000174684(B4GAT1)	--	28.9889	949	20.9414	701	25.4766	855	24.4741	807	25.6236	836	21.6598	711	0.926993938	-0.26420718	normal	0.941667559	0.232202745	normal	0.918348542	-0.273834372	normal	0.676191309	-0.111079237	normal	--	--	--	"K00741|0|pps:100969129|B3GNT1; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; K00741 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.149] (A)"	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Glycosyl-transferase for dystroglycan	"Beta-1,4-glucuronyltransferase 1 {ECO:0000303|PubMed:25279697, ECO:0000303|PubMed:25279699} OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase [Galeopterus variegatus]"
ENSG00000174695(TMEM167A)	--	25.7829	1607	26.253	1644	27.052	1652	28.4582	1806	24.8453	1549	27.3023	1708	0.978914546	0.137471674	normal	0.980583022	-0.107198103	normal	0.984768913	0.039767043	normal	0.932896554	0.024928631	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1242)	Protein kish-A (Precursor) GN=TMEM167A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein kish-A [Capra hircus]
ENSG00000174697(LEP)	--	0	0	0	0	0	0	0.0149431	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; Biological Process: signal transduction (GO:0007165);; 	"K05424|2.04525e-118|hsa:3952|LEP, LEPD, OB, OBS; leptin; K05424 leptin (A)"	Cytokine-cytokine receptor interaction (ko04060);; Neuroactive ligand-receptor interaction (ko04080);; AMPK signaling pathway (ko04152);; Jak-STAT signaling pathway (ko04630);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932)	--	--	Leptin	Leptin (Precursor) GN=LEP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	leptin precursor [Equus caballus]
ENSG00000174705(SH3PXD2B)	--	10.99705056	1625	8.826216229	1430	8.444838517	1374	11.4162967	1840	11.27639953	1746	6.999452853	1164	0.977837898	0.148301958	normal	0.942465276	0.266356576	normal	0.945697574	-0.247286318	normal	0.857800023	0.078375232	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	--	--	--	--	SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; PX domain;; Bacterial SH3 domain;; Bacterial SH3 domain	SH3 and PX domain-containing protein 2B GN=SH3PXD2B OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: SH3 and PX domain-containing protein 2B [Odobenus rosmarus divergens]
ENSG00000174718(KIAA1551)	--	6.40999548	840	8.836609601	908	5.813898579	738	5.651679805	735	5.278258476	693	6.413428	842	0.945886407	-0.22304079	normal	0.696780839	-0.410478326	normal	0.959385101	0.181559434	normal	0.499849418	-0.152260248	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4617)	Uncharacterized protein KIAA1551 GN=KIAA1551 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: uncharacterized protein KIAA1551 homolog [Galeopterus variegatus]
ENSG00000174720(LARP7)	--	12.24312292	618	15.70561016	685	13.6076724	638	11.40441521	579	12.45701379	635	13.02013839	636	0.966109893	-0.124555741	normal	0.965991826	-0.130474683	normal	0.974354072	-0.012790734	normal	0.742525931	-0.090213899	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	"K15191|0|hsa:51574|LARP7, ALAZS, PIP7S; La ribonucleoprotein domain family, member 7; K15191 La-related protein 7 (A)"	--	--	--	"RNA binding motif;; La domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	La-related protein 7 GN=LARP7 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: la-related protein 7 [Vicugna pacos]
ENSG00000174721(FGFBP3)	--	3.08196	124	2.57602	108	3.8229	159	4.13387	170	2.47421	99	2.81612	114	0.844690305	0.419903257	normal	0.963859239	-0.144838301	normal	0.776163437	-0.482835521	normal	0.948801382	-0.051901156	normal	--	--	--	--	--	--	--	FGF binding protein 1 (FGF-BP1)	Fibroblast growth factor-binding protein 3 (Precursor) GN=FGFBP3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: fibroblast growth factor-binding protein 3 [Galeopterus variegatus]
ENSG00000174738(NR1D2)	--	10.1494	806	10.2226	815	9.06166	708	8.90519	715	9.09334	721	10.4093	827	0.952423689	-0.203257155	normal	0.954083133	-0.197836765	normal	0.948583711	0.215420386	normal	0.825301222	-0.062476701	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K08531|0|ggo:101149929|NR1D2; nuclear receptor subfamily 1 group D member 2 isoform 1; K08531 nuclear receptor subfamily 1 group D member 2 (A)	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Nuclear receptor subfamily 1 group D member 2 GN=NR1D2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nuclear receptor subfamily 1 group D member 2 isoform 1 [Canis lupus familiaris]
ENSG00000174740(PABPC5)	--	0.045560555	2	0	0	0	0	0.146692376	6	0.069645271	1	0.157941621	7	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13126|0|ptr:465742|PABPC5; poly(A) binding protein, cytoplasmic 5; K13126 polyadenylate-binding protein (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; RNA degradation (ko03018)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Polyadenylate-binding protein 5 GN=PABPC5 OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: polyadenylate-binding protein 5-like [Tupaia chinensis] 
ENSG00000174744(BRMS1)	--	29.48285984	875	30.14084607	940	34.10986926	1063	36.90444974	1113	39.3114502	1160	30.5165649	917	0.88483147	0.315773809	normal	0.920600668	0.281557186	normal	0.951259355	-0.221100403	normal	0.568862345	0.12708572	normal	--	--	--	--	--	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	Sds3-like	Breast cancer metastasis-suppressor 1 GN=BRMS1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: breast cancer metastasis-suppressor 1 homolog [Bos mutus]
ENSG00000174748(RPL15)	--	1222.127496	18443	1099.466268	16682	1089.479576	16502	1303.088841	20488	1280.134679	20232	1231.688641	18825	0.997091433	0.12086399	normal	0.990832585	0.256898946	normal	0.99526761	0.181701936	normal	0.412240654	0.184339632	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02877|2.20118e-128|mgp:100544398|RPL15; ribosomal protein L15; K02877 large subunit ribosomal protein L15e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L15	60S ribosomal protein L15 GN=RPL15 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	TPA: ribosomal protein L15-like [Bos taurus]
ENSG00000174749(C4orf32)	--	2.1163409	250	1.2252146	143	1.849060386	214	2.826798108	338	2.598971405	309	2.957067923	353	0.774488872	0.4021306	normal	4.99E-05	1.08219591	up	0.040368565	0.709820836	normal	0.001990474	0.699395812	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4605)	Uncharacterized protein C4orf32 GN=C4orf32 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C4orf32 homolog [Canis lupus familiaris]
ENSG00000174775(HRAS)	--	41.53662729	733	45.58579492	826	47.67406161	884	52.19815332	941	46.2062298	780	54.27924773	951	0.863448326	0.328939427	normal	0.971797279	-0.103898426	normal	0.974751645	0.096947597	normal	0.654520284	0.108228819	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K02833|2.97716e-130|rno:293621|Hras, HRAS1, c-H-ras; Harvey rat sarcoma virus oncogene; K02833 GTPase HRas (A)"	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Tight junction (ko04530);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Alcoholism (ko05034);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Thyroid cancer (ko05216);; Melanoma (ko05218);; Bladder cancer (ko05219);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	"GTPase HRas, N-terminally processed (Precursor) GN=HRAS OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	PREDICTED: GTPase HRas isoform X1 [Tupaia chinensis]
ENSG00000174780(SRP72)	--	36.43213219	1969	31.04712564	1888	34.77488112	2062	39.01366763	2212	39.47359721	2200	33.31548761	1849	0.981598575	0.136955149	normal	0.971898295	0.199070371	normal	0.977301026	-0.16546233	normal	0.812661443	0.059493668	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: SRP-dependent cotranslational protein targeting to membrane (GO:0006614);; Molecular Function: 7S RNA binding (GO:0008312);; Cellular Component: signal recognition particle (GO:0048500);; 	K03108|0|pps:100992230|SRP72; signal recognition particle 72kDa; K03108 signal recognition particle subunit SRP72 (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; SRP72 RNA-binding domain;; Anaphase-promoting complex, cyclosome, subunit 3;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Bacterial transcriptional activator domain;; PPR repeat;; Tetratricopeptide repeat"	Signal recognition particle subunit SRP72 GN=SRP72 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle subunit SRP72 isoformX1 [Equus caballus]
ENSG00000174788(PCP2)	--	0.492498	4	0.244058093	1	0.225486	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase regulator activity (GO:0030695);; 	--	--	[T]	Signal transduction mechanisms	GoLoco motif	Purkinje cell protein 2 homolog GN=PCP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: Purkinje cell protein 2 homolog isoform X4 [Canis lupus familiaris]
ENSG00000174791(RIN1)	--	10.50478008	516	9.742977321	485	11.32934019	578	10.452511	514	8.454385572	416	7.350417747	363	0.971451012	-0.036326594	normal	0.93021782	-0.242012037	normal	0.027405521	-0.677135226	normal	0.153054665	-0.310294462	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	K17638|0|hsa:9610|RIN1; Ras and Rab interactor 1; K17638 Ras and Rab interactor 1 (A)	Ras signaling pathway (ko04014)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar sorting protein 9 (VPS9) domain;; Ras association (RalGDS/AF-6) domain	Ras and Rab interactor 1 GN=RIN1 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras and Rab interactor 1 [Pteropus alecto] 
ENSG00000174792(C4orf26)	--	0	0	0	0	0	0	0.602363343	16	0.778590193	14	0.074769249	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C4orf26 (Precursor) GN=C4orf26 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C4orf26 homolog [Ursus maritimus]
ENSG00000174796(THAP6)	--	5.697308368	211	6.011429298	248	5.363467759	248	5.914302302	219	4.517212524	191	5.231545358	213	0.966777768	0.02269341	normal	0.819660348	-0.395437798	normal	0.940150943	-0.226287662	normal	0.558809994	-0.203703288	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 6 GN=THAP6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: THAP domain-containing protein 6 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000174799(CEP135)	--	3.410694	338	3.807385	365	3.93510253	374	3.428538	359	3.148745	323	5.071415	499	0.967277427	0.055881847	normal	0.945810908	-0.196920888	normal	0.725708028	0.40628315	normal	0.794767885	0.112854839	normal	--	--	--	"K16461|0|hsa:9662|CEP135, CEP4, KIAA0635, MCPH8; centrosomal protein 135kDa; K16461 centrosomal protein CEP135 (A)"	--	--	--	--	Centrosomal protein of 135 kDa GN=CEP135 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: centrosomal protein of 135 kDa [Equus przewalskii] 
ENSG00000174804(FZD4)	--	2.07565	249	1.6282	196	1.94265	231	2.57779	310	2.79489	333	2.44798	293	0.911470128	0.283718729	normal	0.031835082	0.738820693	normal	0.877238184	0.332777675	normal	0.072640106	0.44830135	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	K02354|0|cfa:485149|FZD4; frizzled family receptor 4; K02354 frizzled 4 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-4 (Precursor) GN=FZD4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: frizzled-4 [Canis lupus familiaris]
ENSG00000174807(CD248)	--	0	0	0.0198761	1	0.0193257	0	0.0202798	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K06706|0|hsa:57124|CD248, CD164L1, TEM1; CD248 molecule, endosialin; K06706 CD248 antigen, endosialin (A)"	--	--	--	Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; Lectin C-type domain;; Calcium-binding EGF domain	Endosialin (Precursor) GN=CD248 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: endosialin [Ceratotherium simum simum]
ENSG00000174808(BTC)	--	0.941638923	38	1.113319	46	1.574255	62	2.163992005	87	2.03263135	82	2.505774275	92	0.041901297	1.133122032	normal	0.535598412	0.79279624	normal	0.837068085	0.549994525	normal	0.057914776	0.817730688	normal	--	--	--	K09783|1.84864e-97|nle:100590411|BTC; betacellulin; K09783 betacellulin (A)	ErbB signaling pathway (ko04012)	--	--	EGF-like domain;; Human growth factor-like EGF	Betacellulin (Precursor) GN=BTC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: probetacellulin [Equus caballus] 
ENSG00000174827(PDZK1)	--	0.18497879	7	0.210822463	9	0.1453198	5	0.322571556	14	0.291452219	12	0.208550389	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; GRASP55/65 PDZ-like domain;; Tricorn protease PDZ domain	Na(+)/H(+) exchange regulatory cofactor NHE-RF3 GN=PDZK1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Na(+)/H(+) exchange regulatory cofactor NHE-RF3 isoform 1 [Ceratotherium simum simum]
ENSG00000174837(ADGRE1)	--	3.176276702	176	2.563384559	151	2.532985651	156	3.270250589	212	3.145282254	207	4.064387683	255	0.940032523	0.235779131	normal	0.799831333	0.429964288	normal	0.107112369	0.695336357	normal	0.120769357	0.460016069	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04591|0|pps:100995762|EMR1; egf-like module containing, mucin-like, hormone receptor-like 1; K04591 egf-like module containing, mucin-like, hormone receptor-like 1 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Calcium-binding EGF domain;; Complement Clr-like EGF-like;; EGF domain;; MSP1 EGF domain 1;; Latrophilin/CL-1-like GPS domain;; EGF-like domain	EGF-like module-containing mucin-like hormone receptor-like 1 (Precursor) GN=EMR1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: EGF-like module-containing mucin-like hormone receptor-like 1 [Eptesicus fuscus]
ENSG00000174839(DENND6A)	--	4.905746	350	5.457350612	391	4.133622003	290	4.97743835	360	5.588776	399	4.319895	310	0.968751157	0.009767445	normal	0.968771014	0.007763856	normal	0.964486426	0.087482566	normal	0.945223995	0.030249389	normal	--	--	--	--	--	[S]	Function unknown	Stabilization of polarity axis;; Transport protein Avl9;; DENN (AEX-3) domain	Protein DENND6A GN=DENND6A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein DENND6A [Condylura cristata]
ENSG00000174840(PDE12)	--	9.79625	754	9.01405	685	10.22685	723	10.15208	789	10.45293	786	9.08395	720	0.976030321	0.034559671	normal	0.958971215	0.176634505	normal	0.975753943	-0.014260293	normal	0.820323892	0.064716723	normal	[A]	RNA processing and modification	--	--	--	[K]	Transcription	Endonuclease/Exonuclease/phosphatase family	"2',5'-phosphodiesterase 12 (Precursor) GN=PDE12 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: 2',5'-phosphodiesterase 12 [Equus caballus]"
ENSG00000174842(GLMN)	--	5.512811173	168	6.308694291	191	5.246236	147	6.466240413	199	5.541193869	163	4.773551612	146	0.947355135	0.211694524	normal	0.936616533	-0.247999106	normal	0.967860541	-0.017953892	normal	0.985247992	-0.016851479	normal	--	--	--	--	--	--	--	"Uncharacterised protein family, YAP/Alf4/glomulin"	Glomulin GN=GLMN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: glomulin [Ceratotherium simum simum]
ENSG00000174844(DNAH12)	--	0.062458805	3	0.054582882	4	0	0	0.026955432	2	0.051218274	6	0.040864368	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:201625|DNAH12, DHC3, DLP12, DNAH12L, DNAH7L, DNAHC12, DNAHC3, DNHD2, HDHC3, HL-19, HL19; dynein, axonemal, heavy chain 12; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D4;; ATP-binding dynein motor region D5;; P-loop containing dynein motor region D3;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; AAA ATPase domain;; ATPase family associated with various cellular activities (AAA);; RNA helicase"	"Dynein heavy chain 12, axonemal OS=Homo sapiens (Human) PE=2 SV=2"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 12, axonemal isoform X1 [Bison bison bison]"
ENSG00000174851(YIF1A)	--	68.68694101	1130	59.94122109	1029	66.42269304	1125	61.33824	1040	64.81486654	1061	57.694218	986	0.970602003	-0.150358316	normal	0.979415868	0.02272223	normal	0.95995144	-0.198271973	normal	0.629591818	-0.110476598	normal	[S]	Function unknown	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	YIF1;; Yip1 domain	Protein YIF1A GN=YIF1A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein YIF1A isoform X1 [Galeopterus variegatus]
ENSG00000174871(CNIH2)	--	1.737734	35	0.905731	20	1.675323	34	0.508840477	10	0.911554	19	0.672793	14	0.114568551	-1.691266753	normal	0.988135588	-0.088556171	normal	0.659828706	-1.202617568	normal	0.096200137	-1.069059579	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Cornichon protein	Protein cornichon homolog 2 GN=CNIH2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: protein cornichon homolog 2 [Tursiops truncatus]
ENSG00000174891(RSRC1)	--	23.376574	754	28.99813428	901	26.32635953	821	20.625225	763	22.3456351	787	19.660934	705	0.97624736	-0.013686007	normal	0.94978186	-0.216201396	normal	0.943678911	-0.227597525	normal	0.487682981	-0.156320617	normal	--	--	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	--	Serine/Arginine-related protein 53 GN=RSRC1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	"Serine/Arginine-related protein 53, partial [Bos mutus]"
ENSG00000174899(PQLC2L)	--	5.211107083	67	4.769086023	63	3.206569096	40	2.133596805	29	3.322760181	41	3.328027022	41	0.080800272	-1.196049518	normal	0.865779228	-0.622488408	normal	0.981317946	0.026348517	normal	0.242250027	-0.635862858	normal	--	--	--	--	--	--	--	--	Putative uncharacterized protein PQLC2L {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized protein C3orf55 homolog [Equus przewalskii]
ENSG00000174903(RAB1B)	--	79.24878852	2935	79.65955362	3020	83.63561613	3185	82.1324348	3055	88.13320767	3237	84.45644391	3144	0.990078362	0.026965777	normal	0.988990518	0.078644216	normal	0.990470972	-0.026970707	normal	0.933794986	0.025020931	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07875|2.13161e-147|ecb:100058091|RAB1B; RAB1B, member RAS oncogene family; K07875 Ras-related protein Rab-1B (A)"	Legionellosis (ko05134)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase;; Signal recognition particle receptor beta subunit;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-1B GN=RAB1B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-1B isoform 1 [Equus caballus] 
ENSG00000174915(PTDSS2)	--	27.57512	1150	26.15189	1085	27.67475	1202	27.22908	1160	27.3667	1127	29.26118	1239	0.981082998	-0.018316954	normal	0.979870055	0.033320346	normal	0.981441287	0.035403975	normal	0.964032369	0.01601663	normal	--	--	Biological Process: phosphatidylserine biosynthetic process (GO:0006659);; 	"K08730|0|hsa:81490|PTDSS2, PSS2; phosphatidylserine synthase 2 (EC:2.7.8.29); K08730 phosphatidylserine synthase 2 [EC:2.7.8.29] (A)"	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Phosphatidyl serine synthase	Phosphatidylserine synthase 2 GN=PTDSS2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: phosphatidylserine synthase 2 [Odobenus rosmarus divergens]
ENSG00000174917(C19orf70)	--	26.053703	282	27.030811	306	26.036492	302	30.419828	336	29.352713	304	23.071101	254	0.939287287	0.220830514	normal	0.966544689	-0.030734496	normal	0.926048126	-0.2566085	normal	0.980078112	-0.015509781	normal	--	--	--	--	--	--	--	--	Protein QIL1 GN=QIL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PANDA_017622 [Ailuropoda melanoleuca]
ENSG00000174928(C3orf33)	--	6.992378	198	6.99821	200	6.80958	192	5.520434479	159	7.795228477	220	5.194612	148	0.890971909	-0.344317382	normal	0.960394218	0.115245896	normal	0.865661732	-0.380378229	normal	0.639329075	-0.184165317	normal	--	--	--	--	--	--	--	--	Protein C3orf33 GN=C3orf33 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C3orf33 homolog [Orcinus orca]
ENSG00000174938(SEZ6L2)	--	19.32555273	1448	16.96682677	1103	16.71191379	1220	8.42769922	629	12.14856673	799	9.31695696	657	9.37E-11	-1.231718255	down	0.414846033	-0.485805665	normal	2.60E-05	-0.899662898	normal	6.74E-06	-0.875870951	normal	--	--	--	--	--	--	--	Sushi domain (SCR repeat);; CUB domain	Seizure 6-like protein 2 (Precursor) GN=SEZ6L2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: seizure 6-like protein 2 isoform X1 [Vicugna pacos]
ENSG00000174939(ASPHD1)	--	20.80161266	394	22.56651165	444	19.45781229	391	11.521444	237	11.99240362	228	6.864318013	153	0.011695177	-0.760273929	normal	8.09E-05	-0.978213424	normal	6.00E-09	-1.353251133	down	6.58E-07	-1.014305353	down	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: peptidyl-amino acid modification (GO:0018193);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Aspartyl/Asparaginyl beta-hydroxylase	Aspartate beta-hydroxylase domain-containing protein 1 GN=ASPHD1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: aspartate beta-hydroxylase domain-containing protein 1 [Trichechus manatus latirostris]
ENSG00000174943(KCTD13)	--	8.909853798	343	9.2685534	328	10.72935202	350	7.18111	257	6.951501672	241	9.589770831	344	0.674341096	-0.444960788	normal	0.640929777	-0.463584998	normal	0.968256041	-0.033093564	normal	0.254312962	-0.298348411	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	K15074|0|ptr:454030|KCTD13; potassium channel tetramerization domain containing 13; K15074 BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein (A)	--	[P]	Inorganic ion transport and metabolism	BTB/POZ domain	BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 [Oryctolagus cuniculus]
ENSG00000174944(P2RY14)	--	0	0	0.0763554	2	0	0	0	0	0.0361315	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04299|0|hsa:9934|P2RY14, BPR105, GPR105, P2Y14; purinergic receptor P2Y, G-protein coupled, 14; K04299 purinergic receptor P2Y, G protein-coupled, 14 (A)"	Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family)	P2Y purinoceptor 14 GN=P2RY14 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: P2Y purinoceptor 14 [Leptonychotes weddellii]
ENSG00000174945(AMZ1)	--	0.018956963	2	0.064570267	7	0.045594654	4	0.028369097	3	0.00921822	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06974|0|ptr:738827|AMZ1; archaelysin family metallopeptidase 1; K06974 archaemetzincin [EC:3.4.-.-] (A)	--	--	--	Peptidase family M54	Archaemetzincin-1 GN=AMZ1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: archaemetzincin-1 isoform X1 [Tupaia chinensis] 
ENSG00000174946(GPR171)	--	0	0	0	0	0	0	0.0845163	2	0	0	0.087571852	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08441|0|ptr:738791|GPR171; G protein-coupled receptor 171; K08441 G protein-coupled receptor 171 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 171 GN=GPR171 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 171 [Balaenoptera acutorostrata scammoni]
ENSG00000174951(FUT1)	--	0.0418538	3	0.0136041	1	0.0134099	0	0	0	0	0	0.0689824	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: galactoside 2-alpha-L-fucosyltransferase activity (GO:0008107);; Cellular Component: membrane (GO:0016020);; 	"K00718|0|hsa:2523|FUT1, H, HH, HSC; fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) (EC:2.4.1.69); K00718 galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601);; Glycosphingolipid biosynthesis - globo series (ko00603)	--	--	Glycosyl transferase family 11	Galactoside 2-alpha-L-fucosyltransferase 1 GN=FUT1 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: galactoside 2-alpha-L-fucosyltransferase 1 [Canis lupus familiaris]
ENSG00000174953(DHX36)	--	25.99955291	1877	30.76560939	2255	30.26261699	2045	26.38576546	1945	27.77730635	2080	25.71944271	1829	0.986339141	0.020492763	normal	0.981700532	-0.137874154	normal	0.976601976	-0.169204825	normal	0.657148143	-0.098857358	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	K14442|0|pps:100973357|DHX36; DEAH (Asp-Glu-Ala-His) box polypeptide 36; K14442 ATP-dependent RNA helicase DHX36 [EC:3.6.4.13] (A)	RNA degradation (ko03018)	[A]	RNA processing and modification	Helicase associated domain (HA2);; Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; AAA domain	ATP-dependent RNA helicase DHX36 GN=DHX36 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DHX36 [Oryctolagus cuniculus]
ENSG00000174963(ZIC4)	--	0.016378195	1	0.183025037	6	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09225|0|hsa:84107|ZIC4; Zic family member 4; K09225 zinc finger protein ZIC 4 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein ZIC 4 GN=ZIC4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein ZIC 4 [Oryctolagus cuniculus]
ENSG00000174989(FBXW8)	--	6.243673142	619	5.5729832	612	5.182907	509	7.328078593	825	8.499090477	889	8.512098	911	0.761629818	0.382797033	normal	0.308064485	0.51616132	normal	0.00034895	0.829626008	normal	0.000444169	0.572031734	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10264|0|nle:100595548|FBXW8; F-box and WD repeat domain containing 8; K10264 F-box and WD-40 domain protein 8 (A)	Ubiquitin mediated proteolysis (ko04120)	[R]	General function prediction only	"F-box-like;; WD domain, G-beta repeat;; F-box domain"	F-box/WD repeat-containing protein 8 GN=FBXW8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box/WD repeat-containing protein 8 [Galeopterus variegatus]
ENSG00000174992(ZG16)	--	0	0	0.0156845	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Jacalin-like lectin domain	Zymogen granule membrane protein 16 (Precursor) GN=ZG16 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zymogen granule membrane protein 16 [Eptesicus fuscus]
ENSG00000174996(KLC2)	--	21.17009408	1272	18.39458937	1140	21.33261561	1309	19.60242243	1176	18.30605901	1134	20.04517061	1243	0.973401404	-0.143862081	normal	0.980293077	-0.029001169	normal	0.979952537	-0.082832026	normal	0.713277133	-0.087525188	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10407|0|ptr:466670|KLC2; kinesin light chain 2; K10407 kinesin light chain (A)	Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Tetratricopeptide repeat;; Rabaptin-like protein;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Soluble NSF attachment protein, SNAP"	Kinesin light chain 2 GN=KLC2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: kinesin light chain 2 [Tupaia chinensis]
ENSG00000175003(SLC22A1)	--	0.050201168	1	0.041590301	1	0.076268118	1	0.80072977	20	0.738836985	18	0.468016453	12	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08198|0|hsa:6580|SLC22A1, HOCT1, OCT1, oct1_cds; solute carrier family 22 (organic cation transporter), member 1; K08198 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 1 (A)"	Bile secretion (ko04976);; Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 1 GN=SLC22A1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: solute carrier family 22 member 1 [Ceratotherium simum simum]
ENSG00000175018(TEX36)	--	0	0	0	0	0	0	0	0	0	0	0.0697836	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function with conserved HDNR motif	Testis-expressed sequence 36 protein GN=TEX36 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 36 protein [Ailuropoda melanoleuca]
ENSG00000175029(CTBP2)	--	37.64383992	2237	34.65941377	2137	39.1277675	2181	39.58467423	2466	33.79768447	2231	37.38218069	2431	0.985142025	0.109703501	normal	0.986928465	0.040648894	normal	0.981691473	0.148171324	normal	0.652988426	0.099631107	normal	[HE]	Coenzyme transport and metabolism;; Amino acid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: NAD binding (GO:0051287);; Biological Process: oxidation-reduction process (GO:0055114);; "	K04496|0|pps:100983301|CTBP2; C-terminal binding protein 2; K04496 C-terminal binding protein (A)	Wnt signaling pathway (ko04310);; Notch signaling pathway (ko04330);; Pathways in cancer (ko05200);; Chronic myeloid leukemia (ko05220)	[K]	Transcription	"D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain;; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain"	C-terminal-binding protein 2 GN=CTBP2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: C-terminal-binding protein 2 isoform X1 [Galeopterus variegatus]
ENSG00000175040(CHST2)	--	1.33837	97	0.532879	40	1.09988	83	0.776825	57	0.91679	67	1.19397	88	0.420568167	-0.781509237	normal	0.787505161	0.702024511	normal	0.971358645	0.074777405	normal	0.945365239	-0.072805668	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	K04745|0|mcf:102116327|CHST2; carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2; K04745 carbohydrate 6-sulfotransferase 2 [EC:2.8.2.-] (A)	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533)	--	--	Sulfotransferase domain;; Sulfotransferase family	Carbohydrate sulfotransferase 2 GN=CHST2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: carbohydrate sulfotransferase 2 [Oryctolagus cuniculus]
ENSG00000175048(ZDHHC14)	--	2.94227325	191	2.062550698	160	3.253845734	219	2.504358651	164	2.034158593	140	1.910024388	121	0.937991025	-0.248548797	normal	0.949083499	-0.211928357	normal	0.015672168	-0.856144426	normal	0.1684059	-0.445176136	normal	[R]	General function prediction only	--	"K16675|0|pon:100452336|ZDHHC14; zinc finger, DHHC-type containing 14; K16675 palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC14 GN=ZDHHC14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	probable palmitoyltransferase ZDHHC14 [Bos taurus] 
ENSG00000175054(ATR)	--	9.280679152	1295	8.689632597	1325	9.07156914	1301	9.307370888	1365	9.839037862	1315	9.571644198	1352	0.982088999	0.045064512	normal	0.981934326	-0.032319091	normal	0.982045043	0.047129006	normal	0.954684329	0.019026623	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: protein binding (GO:0005515);; Molecular Function: kinase activity (GO:0016301);; 	"K06640|0|hsa:545|ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1; ATR serine/threonine kinase (EC:2.7.11.1); K06640 serine/threonine-protein kinase ATR [EC:2.7.11.1] (A)"	Fanconi anemia pathway (ko03460);; Cell cycle (ko04110);; p53 signaling pathway (ko04115);; HTLV-I infection (ko05166)	[TBLD]	"Signal transduction mechanisms;; Chromatin structure and dynamics;; Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	Phosphatidylinositol 3- and 4-kinase;; FAT domain;; UME (NUC010) domain;; FATC domain;; HEAT repeat	Serine/threonine-protein kinase ATR GN=ATR OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: serine/threonine-protein kinase ATR [Ailuropoda melanoleuca]
ENSG00000175063(UBE2C)	--	105.52494	1184	89.12790221	1060	104.358758	1213	91.904899	1083	78.003989	888	75.894048	877	0.969801803	-0.159251921	normal	0.92226256	-0.276427712	normal	0.435847506	-0.475521859	normal	0.080518967	-0.301303545	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 C GN=UBE2C OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 C isoform 1 [Equus caballus] 
ENSG00000175065(DSG4)	--	0.012261728	1	0.014044987	1	0.024361882	1	0.028220335	2	0	0	0.023597672	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K07599|0|hsa:147409|DSG4, CDGF13, CDHF13, HYPT6, LAH; desmoglein 4; K07599 desmoglein 4 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region	Desmoglein-4 (Precursor) GN=DSG4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: desmoglein-4 [Canis lupus familiaris]
ENSG00000175066(GK5)	--	2.697106561	436	3.334581	494	3.396588499	455	5.276626	526	3.131791511	447	2.7116993	438	0.932223429	0.239134324	normal	0.955773568	-0.165131062	normal	0.968960376	-0.063013637	normal	0.99253506	0.004973454	normal	[C]	Energy production and conversion	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	--	--	[G]	Carbohydrate transport and metabolism	"FGGY family of carbohydrate kinases, N-terminal domain;; FGGY family of carbohydrate kinases, C-terminal domain"	Putative glycerol kinase 5 GN=GK5 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: putative glycerol kinase 5 isoform 1 [Dasypus novemcinctus]
ENSG00000175073(VCPIP1)	--	5.2215	794	6.1392	936	5.92629	886	6.27503	964	5.63256	856	6.56618	1000	0.936127615	0.248624721	normal	0.967361311	-0.150070638	normal	0.965687472	0.166063005	normal	0.728258727	0.087207279	normal	--	--	--	"K11861|0|hsa:80124|VCPIP1, DUBA3, VCIP135; valosin containing protein (p97)/p47 complex interacting protein 1 (EC:3.4.19.12); K11861 deubiquitinating protein VCIP135 [EC:3.4.19.12] (A)"	--	[T]	Signal transduction mechanisms	OTU-like cysteine protease	Deubiquitinating protein VCIP135 GN=VCPIP1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: deubiquitinating protein VCIP135 [Galeopterus variegatus]
ENSG00000175084(DES)	--	0.0208084	1	0	0	0.0398946	1	0	0	0.020163	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	K07610|0|ptr:470657|DES; desmin; K07610 desmin (A)	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	--	--	Intermediate filament protein;; Intermediate filament head (DNA binding) region	Desmin GN=DES OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: desmin [Camelus dromedarius]
ENSG00000175087(PDIK1L)	--	2.073096032	128	2.0252107	119	2.063280639	120	2.40672978	151	2.861263297	134	2.840363	177	0.953411879	0.205301735	normal	0.960871394	0.148070854	normal	0.621071799	0.546716445	normal	0.431579487	0.311311313	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K17539|0|ptr:736983|PDIK1L; PDLIM1 interacting kinase 1 like; K17539 serine/threonine-protein kinase PDIK1L [EC:2.7.11.1] (A)	--	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase PDIK1L GN=PDIK1L OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase PDIK1L isoform X2 [Sus scrofa]
ENSG00000175093(SPSB4)	--	0.0399162	2	0.058455	3	0.0380407	1	0	0	0.019276	0	0.118044	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10343|0|ptr:460739|SPSB4; splA/ryanodine receptor domain and SOCS box containing 4; K10343 SPRY domain-containing SOCS box protein 1/4 (A)	--	[R]	General function prediction only	SPRY domain;; SOCS box	SPRY domain-containing SOCS box protein 4 GN=SPSB4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SPRY domain-containing SOCS box protein 4 [Orycteropus afer afer]
ENSG00000175104(TRAF6)	--	3.548144569	346	3.692531346	371	2.93248109	298	3.810799162	360	4.328982976	437	3.972277548	415	0.968450799	0.026278208	normal	0.941057797	0.213983133	normal	0.577142747	0.467488408	normal	0.368965262	0.234866795	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K03175|0|hsa:7189|TRAF6, MGC:3310, RNF85; TNF receptor-associated factor 6, E3 ubiquitin protein ligase; K03175 TNF receptor-associated factor 6 (A)"	MAPK signaling pathway (ko04010);; NF-kappa B signaling pathway (ko04064);; Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Neurotrophin signaling pathway (ko04722);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Measles (ko05162);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[T]	Signal transduction mechanisms	"TRAF-type zinc finger;; MATH domain;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	TNF receptor-associated factor 6 GN=TRAF6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: TNF receptor-associated factor 6 [Galeopterus variegatus]
ENSG00000175105(ZNF654)	--	2.9998671	320	3.79222	402	3.658032037	380	4.680907	483	3.637365	378	4.26096827	455	0.232536607	0.560913145	normal	0.962920963	-0.109809726	normal	0.926239398	0.250662893	normal	0.352956672	0.234598099	normal	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type"	Zinc finger protein 654 GN=ZNF654 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 654 [Oryctolagus cuniculus]
ENSG00000175106(TVP23C)	--	10.99095682	794	8.91527113	826	9.151343073	780	8.24024589	731	8.927704602	856	11.66777359	968	0.965393835	-0.149797638	normal	0.976667872	0.029988524	normal	0.896051243	0.302713673	normal	0.799642535	0.069882644	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Eukaryotic protein of unknown function (DUF846)	Golgi apparatus membrane protein TVP23 homolog C GN=TVP23C OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: Golgi apparatus membrane protein TVP23 homolog B isoform X1 [Galeopterus variegatus]
ENSG00000175110(MRPS22)	--	18.084202	337	18.912511	353	18.6618785	345	20.928902	397	23.207661	431	16.428434	307	0.944432651	0.204697617	normal	0.917554372	0.265562086	normal	0.952027836	-0.175831588	normal	0.72986082	0.111244152	normal	--	--	--	"K17401|0|hsa:56945|MRPS22, C3orf5, COXPD5, GIBT, MRP-S22, RPMS22; mitochondrial ribosomal protein S22; K17401 small subunit ribosomal protein S22 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial 28S ribosomal protein S22	"28S ribosomal protein S22, mitochondrial GN=MRPS22 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S22, mitochondrial [Ceratotherium simum simum]"
ENSG00000175115(PACS1)	--	24.5809	2336	21.67083925	1881	23.68383939	2316	33.84043895	3125	36.04446169	3645	27.20482459	2438	0.815274201	0.388761915	normal	4.72E-06	0.932444464	normal	0.98735909	0.065729595	normal	0.086858387	0.473628024	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PACS-1 cytosolic sorting protein	Phosphofurin acidic cluster sorting protein 1 GN=PACS1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: phosphofurin acidic cluster sorting protein 1, partial [Tupaia chinensis]"
ENSG00000175130(MARCKSL1)	--	27.8728	813	19.5497	588	27.6206	833	57.0099	1676	65.5522	1907	45.8011	1351	3.67E-07	1.011503857	up	0	1.673464095	up	0.008369343	0.688357209	normal	4.82E-06	1.121841057	up	--	--	Molecular Function: calmodulin binding (GO:0005516);; 	"K13536|3.69285e-48|rno:81520|Marcksl1, F52, Mlp; MARCKS-like 1; K13536 MARCKS-related protein (A)"	Fc gamma R-mediated phagocytosis (ko04666);; Leishmaniasis (ko05140)	--	--	MARCKS family	MARCKS-related protein GN=MARCKSL1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	TPA: MARCKS-related protein [Bos taurus]
ENSG00000175137(SH3BP5L)	--	8.95809753	593	8.712015066	610	9.722986396	629	12.55745817	837	12.2794	771	11.28506249	737	0.490819858	0.465344036	normal	0.879043078	0.3157973	normal	0.944999945	0.219824429	normal	0.071547081	0.334657458	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	SH3 domain-binding protein 5 (SH3BP5)	SH3 domain-binding protein 5-like GN=SH3BP5L OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH3 domain-binding protein 5-like isoform X1 [Sus scrofa] 
ENSG00000175155(YPEL2)	--	1.712497924	148	2.078882736	181	1.846966181	159	2.3119752	201	2.726579299	235	3.958994257	343	0.834932662	0.407127385	normal	0.872391945	0.35265225	normal	1.60E-05	1.093637508	up	0.122256733	0.655053652	normal	--	--	--	--	--	[R]	General function prediction only	"Yippee zinc-binding/DNA-binding /Mis18, centromere assembly"	Protein yippee-like 2 GN=YPEL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein yippee-like 2 isoform X2 [Monodelphis domestica]
ENSG00000175161(CADM2)	--	0.007674938	1	0.023158338	3	0.007744408	0	0.140614371	4	0.173144024	12	0.090656411	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06782|0|mcc:719312|CADM2; cell adhesion molecule 2; K06782 cell adhesion molecule 2 (A)	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin C1-set domain	Cell adhesion molecule 2 (Precursor) GN=CADM2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: cell adhesion molecule 2 isoform X1 [Bos taurus] 
ENSG00000175166(PSMD2)	--	97.110131	5721	99.3102583	5695	108.14726	6054	149.42066	8177	132.573854	7578	101.7899367	5647	0.587989077	0.484362718	normal	0.891151725	0.390604549	normal	0.992561023	-0.108667373	normal	0.265520316	0.270751196	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K03028|0|pon:100172819|PSMD2; proteasome (prosome, macropain) 26S subunit, non-ATPase, 2; K03028 26S proteasome regulatory subunit N1 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome/cyclosome repeat	26S proteasome non-ATPase regulatory subunit 2 GN=PSMD2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 2 [Bos mutus]
ENSG00000175170(FAM182B)	--	0	0	0.22776118	2	0.09705642	1	0.032770733	1	0	0	0.09793477	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM182B GN=FAM182B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	--
ENSG00000175175(PPM1E)	--	0.150166	17	0.0526023	6	0.113924	12	0.0704239	8	0.0428206	4	0.122741	14	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	"K17501|0|hsa:22843|PPM1E, CaMKP-N, POPX1, PP2CH, caMKN; protein phosphatase, Mg2+/Mn2+ dependent, 1E (EC:3.1.3.16); K17501 protein phosphatase 1E [EC:3.1.3.16] (A)"	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C	Protein phosphatase 1E GN=PPM1E OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protein phosphatase 1E [Equus caballus]
ENSG00000175182(FAM131A)	--	3.968640236	147	5.142804749	181	5.63682	170	5.62554	184	4.312266004	148	3.462642813	147	0.925171175	0.290340442	normal	0.91499174	-0.308958965	normal	0.948831091	-0.215942308	normal	0.883493494	-0.078045776	normal	--	--	--	--	--	--	--	Putative cell signalling	Protein FAM131A (Precursor) GN=FAM131A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM131A isoform X1 [Mustela putorius furo] 
ENSG00000175183(CSRP2)	--	17.99573356	246	17.49109637	235	19.96289116	278	19.90549484	280	14.96255137	196	17.11057808	240	0.955906763	0.15502827	normal	0.918463938	-0.281248757	normal	0.94114688	-0.219058166	normal	0.78854852	-0.105696162	normal	--	--	--	K09377|1.49714e-111|ptr:452089|CSRP2; cysteine and glycine-rich protein 2; K09377 cysteine and glycine-rich protein (A)	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	Cysteine and glycine-rich protein 2 GN=CSRP2 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: cysteine and glycine-rich protein 2 isoform X1 [Capra hircus]
ENSG00000175189(INHBC)	--	0.201085	7	0.0285679	1	0.0843941	2	0.0288689	1	0.0280061	0	0.0283018	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	"K04667|0|hsa:3626|INHBC, IHBC; inhibin, beta C; K04667 inhibin, beta (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[T]	Signal transduction mechanisms	Transforming growth factor beta like domain;; TGF-beta propeptide	Inhibin beta C chain (Precursor) GN=INHBC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inhibin beta C chain [Galeopterus variegatus]
ENSG00000175193(PARL)	--	33.25168363	695	32.31241216	661	30.5553324	641	39.45439187	798	36.522349	789	30.49358537	665	0.961451577	0.168196312	normal	0.940057065	0.233459066	normal	0.973851264	0.04463515	normal	0.514305344	0.151595846	normal	[R]	General function prediction only	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09650|0|ggo:101136818|PARL; presenilins-associated rhomboid-like protein, mitochondrial isoform 1; K09650 rhomboid-like protein [EC:3.4.21.105] (A)"	--	[T]	Signal transduction mechanisms	Rhomboid family	P-beta (Precursor) GN=PARL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: presenilins-associated rhomboid-like protein, mitochondrial [Ailuropoda melanoleuca] "
ENSG00000175197(DDIT3)	--	9.956776	177	11.96594118	217	9.22455	166	8.03694	145	6.192058	110	19.19653	346	0.914665759	-0.315496986	normal	0.001823496	-0.991718835	normal	4.82E-05	1.044561087	up	0.957636091	0.083137943	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04452|1.67578e-86|pps:100982590|DDIT3; DNA-damage-inducible transcript 3; K04452 DNA damage-inducible transcript 3 (A)	MAPK signaling pathway (ko04010);; Protein processing in endoplasmic reticulum (ko04141);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	Basic region leucine zipper	DNA damage-inducible transcript 3 protein GN=DDIT3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA damage-inducible transcript 3 protein isoform X2 [Galeopterus variegatus]
ENSG00000175198(PCCA)	--	8.712680633	374	8.340020528	345	9.745146852	341	9.512109545	387	14.61980775	408	12.47871038	457	0.969148077	0.018388771	normal	0.938772977	0.219659987	normal	0.718605833	0.412545186	normal	0.403410084	0.219404983	normal	[I]	Lipid transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; 	"K01965|0|hsa:5095|PCCA; propionyl CoA carboxylase, alpha polypeptide (EC:6.4.1.3); K01965 propionyl-CoA carboxylase alpha chain [EC:6.4.1.3] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; Glyoxylate and dicarboxylate metabolism (ko00630);; Propanoate metabolism (ko00640)"	[IE]	Lipid transport and metabolism;; Amino acid transport and metabolism	"Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; Biotin-requiring enzyme;; ATP-grasp domain;; D-ala D-ala ligase C-terminus;; Biotin-lipoyl like;; RimK-like ATP-grasp domain;; ATP-grasp domain;; HlyD family secretion protein"	"Propionyl-CoA carboxylase alpha chain, mitochondrial (Precursor) GN=PCCA OS=Homo sapiens (Human) PE=1 SV=4"	C	Energy production and conversion	"PREDICTED: propionyl-CoA carboxylase alpha chain, mitochondrial isoform X1 [Felis catus]"
ENSG00000175203(DCTN2)	--	55.4540239	2006	54.429294	1926	60.82457317	2195	67.335317	2399	71.696643	2522	71.096045	2425	0.966293207	0.227120058	normal	0.852429733	0.367281322	normal	0.982975672	0.135383592	normal	0.163677666	0.240857176	normal	--	--	Biological Process: mitotic cell cycle (GO:0000278);; Cellular Component: dynactin complex (GO:0005869);; Biological Process: microtubule-based process (GO:0007017);; 	K10424|0|tup:102498807|DCTN2; dynactin 2 (p50); K10424 dynactin 2 (A)	Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016)	[Z]	Cytoskeleton	Dynamitin	Dynactin subunit 2 GN=DCTN2 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: dynactin subunit 2 isoform X1 [Tupaia chinensis]
ENSG00000175206(NPPA)	--	0	0	0.074124778	1	0.0728147	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K12334|1.24988e-80|ptr:736416|NPPA; natriuretic peptide A; K12334 natriuretic peptide A (A)	HIF-1 signaling pathway (ko04066)	--	--	Atrial natriuretic peptide	Atrial natriuretic factor (Precursor) GN=NPPA OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: natriuretic peptides A [Pteropus alecto]
ENSG00000175213(ZNF408)	--	5.764259336	267	5.74914848	246	5.23862756	233	7.36883679	343	7.382235476	330	6.76931112	305	0.873629393	0.328863345	normal	0.782445046	0.400249963	normal	0.823374505	0.378037139	normal	0.147476847	0.368975826	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Drought induced 19 protein (Di19), zinc-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 408 GN=ZNF408 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 408 [Galeopterus variegatus]
ENSG00000175215(CTDSP2)	--	30.0067938	2303	29.69445296	2337	28.54919076	2212	32.64939527	2417	36.50592512	2649	41.86417615	3122	0.987981524	0.038845501	normal	0.981194725	0.159266702	normal	0.428891892	0.488545221	normal	0.189492162	0.236480718	normal	[K]	Transcription	--	"K15731|0|ptr:746009|CTDSP2; CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2; K15731 carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase [EC:3.1.3.16] (A)"	--	[K]	Transcription	NLI interacting factor-like phosphatase	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 GN=CTDSP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2-like [Ceratotherium simum simum]
ENSG00000175216(CKAP5)	--	35.6423298	5465	39.95093498	5389	46.04718484	5391	40.94303982	5804	35.54712946	5401	43.150965	5369	0.993631344	0.055978488	normal	0.993553921	-0.018212491	normal	0.99375644	-0.014186959	normal	0.984925516	0.007475243	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16803|0|hsa:9793|CKAP5, CHTOG, MSPS, TOG, TOGp, ch-TOG; cytoskeleton associated protein 5; K16803 cytoskeleton-associated protein 5 (A)"	--	[Z]	Cytoskeleton	CLASP N terminal;; HEAT repeat;; HEAT repeats;; Vacuolar 14 Fab1-binding region;; HEAT repeat associated with sister chromatid cohesion	Cytoskeleton-associated protein 5 GN=CKAP5 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: cytoskeleton-associated protein 5 isoform X1 [Physeter catodon] 
ENSG00000175220(ARHGAP1)	--	19.093439	1204	20.53471	1277	19.902553	1266	30.35098	1886	29.668209	1847	26.37882	1680	0.041057135	0.616029152	normal	0.318745358	0.510493485	normal	0.739484941	0.399476821	normal	0.000493787	0.509200879	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K18470|0|hsa:392|ARHGAP1, CDC42GAP, RHOGAP, RHOGAP1, p50rhoGAP; Rho GTPase activating protein 1; K18470 Rho GTPase-activating protein 1 (A)"	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	RhoGAP domain;; Divergent CRAL/TRIO domain;; CRAL/TRIO domain	Rho GTPase-activating protein 1 GN=ARHGAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 1 [Felis catus]
ENSG00000175221(MED16)	--	16.40210261	494	22.6057487	539	14.91166851	526	10.10115766	441	13.43869136	552	17.70585704	602	0.949054188	-0.193925825	normal	0.971908628	0.012920615	normal	0.953471015	0.185909276	normal	0.980122653	0.012718983	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K15159|0|hsa:10025|MED16, DRIP92, THRAP5, TRAP95; mediator complex subunit 16; K15159 mediator of RNA polymerase II transcription subunit 16 (A)"	Thyroid hormone signaling pathway (ko04919)	--	--	"Mediator complex subunit 16;; WD domain, G-beta repeat"	Mediator of RNA polymerase II transcription subunit 16 GN=MED16 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 16 isoform 1 [Ceratotherium simum simum] 
ENSG00000175224(ATG13)	--	24.11122842	1519	35.7943096	1995	28.96099764	1622	27.40040069	1522	25.65664746	1496	32.43095649	2009	0.983950526	-0.027957524	normal	0.641828892	-0.436321734	normal	0.922798743	0.300160387	normal	0.903207025	-0.051523787	normal	--	--	Biological Process: autophagy (GO:0006914);; Cellular Component: ATG1/UKL1 kinase complex (GO:1990316);; 	K08331|0|mcf:101865971|Autophagy-related protein 13; K08331 autophagy-related protein 13 (A)	Regulation of autophagy (ko04140)	[S]	Function unknown	Autophagy-related protein 13	Autophagy-related protein 13 GN=ATG13 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: autophagy-related protein 13 isoform X4 [Myotis brandtii] 
ENSG00000175229(GAL3ST3)	--	0	0	0.0674091	2	0.0323022	0	0	0	0.065770655	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: galactosylceramide sulfotransferase activity (GO:0001733);; Cellular Component: Golgi apparatus (GO:0005794);; Biological Process: glycolipid biosynthetic process (GO:0009247);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09676|0|hsa:89792|GAL3ST3, GAL3ST-3, GAL3ST2; galactose-3-O-sulfotransferase 3; K09676 galactose-3-O-sulfotransferase 3 [EC:2.8.2.-] (A)"	--	--	--	Galactose-3-O-sulfotransferase;; Sulfotransferase family	Galactose-3-O-sulfotransferase 3 GN=GAL3ST3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: galactose-3-O-sulfotransferase 3-like [Tupaia chinensis]
ENSG00000175262(C1orf127)	--	0	0	0	0	0.080723258	3	0	0	0.040647821	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4556)	Uncharacterized protein C1orf127 GN=C1orf127 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C1orf127 homolog [Galeopterus variegatus]
ENSG00000175264(CHST1)	--	0.595072	28	0.1858598	9	0.584181	28	0.402097342	19	0.612629	29	0.083721125	4	0.972503104	-0.553186227	normal	0.469893569	1.517959786	normal	0.017465671	-2.427534542	normal	0.831092618	-0.344286921	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	K01022|0|ptr:466500|CHST1; carbohydrate (keratan sulfate Gal-6) sulfotransferase 1; K01022 keratan sulfate 6-sulfotransferase 1 [EC:2.8.2.21] (A)	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533)	--	--	Sulfotransferase domain	Carbohydrate sulfotransferase 1 GN=CHST1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: carbohydrate sulfotransferase 1 [Physeter catodon]
ENSG00000175265(GOLGA8A)	--	2.929930963	270	2.853030744	267	2.844360419	264	2.207090771	204	2.730540812	250	3.071610662	283	0.746276827	-0.432381355	normal	0.960258161	-0.11566103	normal	0.963844011	0.091466539	normal	0.691174648	-0.140354593	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5;; Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8A GN=GOLGA8A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	"golgi autoantigen, golgin subfamily a, 2 isoform 1 [Camelus ferus]"
ENSG00000175274(TP53I11)	--	34.956212	1627	31.55677647	1320	48.70336203	1394	34.28696726	1554	43.018912	2114	36.824991	1721	0.981627915	-0.096966301	normal	0.018924549	0.657410585	normal	0.921085393	0.295436137	normal	0.243199655	0.291167828	normal	--	--	--	--	--	--	--	Tumour protein p53-inducible protein 11	Tumor protein p53-inducible protein 11 GN=TP53I11 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: tumor protein p53-inducible protein 11 [Galeopterus variegatus] 
ENSG00000175279(CENPS)	--	20.76258636	326	19.788063	340	21.770075	365	23.98540859	391	19.465329	323	20.34018296	335	0.935261742	0.230471529	normal	0.96331137	-0.094993573	normal	0.96036411	-0.131458086	normal	0.998695285	0.003397484	normal	--	--	Cellular Component: FANCM-MHF complex (GO:0071821);; 	"K11511|5.28206e-90|nle:100600088|APITD1; apoptosis-inducing, TAF9-like domain 1; K11511 centromere protein S (A)"	Fanconi anemia pathway (ko03460)	--	--	Kinetochore component CENP-S	Centromere protein S GN=APITD1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: centromere protein S-like isoform 2 [Ceratotherium simum simum]
ENSG00000175283(DOLK)	--	20.6909	665	24.3629	801	22.4165	734	18.7939	605	19.7884	631	22.1619	713	0.95947439	-0.166847096	normal	0.806659858	-0.36481073	normal	0.974823374	-0.050064765	normal	0.366634255	-0.19550407	normal	[I]	Lipid transport and metabolism	--	K00902|0|ssc:100152320|DOLK; dolichol kinase; K00902 dolichol kinase [EC:2.7.1.108] (A)	N-Glycan biosynthesis (ko00510)	[I]	Lipid transport and metabolism	--	Dolichol kinase GN=DOLK OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: dolichol kinase [Sus scrofa]
ENSG00000175294(CATSPER1)	--	0.428558906	21	0.288081179	14	0.158453219	7	0.6071933	30	0.829089	40	0.3983827	20	0.976612711	0.455729419	normal	0.253663922	1.400135292	normal	0.884359527	1.330278725	normal	0.100259253	1.076344505	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K16889|0|hsa:117144|CATSPER1, CATSPER, SPGF7; cation channel, sperm associated 1; K16889 cation channel sperm-associated protein 1 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Polycystin cation channel	Cation channel sperm-associated protein 1 GN=CATSPER1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: cation channel sperm-associated protein 1 [Oryctolagus cuniculus]
ENSG00000175305(CCNE2)	--	4.407025422	173	6.014954418	218	6.258346992	235	6.67719	268	5.043383232	198	4.193585	153	0.306169847	0.596343261	normal	0.954822025	-0.159095644	normal	0.282491911	-0.62241792	normal	0.958484282	-0.038848474	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cellular Component: nucleus (GO:0005634);; 	"K06626|0|hsa:9134|CCNE2, CYCE2; cyclin E2; K06626 cyclin E (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; p53 signaling pathway (ko04115);; PI3K-Akt signaling pathway (ko04151);; Hepatitis B (ko05161);; Measles (ko05162);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; MicroRNAs in cancer (ko05206);; Prostate cancer (ko05215);; Small cell lung cancer (ko05222)	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain;; Cyclin, C-terminal domain"	G1/S-specific cyclin-E2 GN=CCNE2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: G1/S-specific cyclin-E2 [Ursus maritimus]
ENSG00000175309(PHYKPL)	--	2.872014	96	3.271068	100	2.82954	84	2.56964315	89	3.58352	107	3.120103014	92	0.967664934	-0.137770504	normal	0.967873374	0.075086393	normal	0.969125933	0.120873126	normal	0.985893701	0.019361021	normal	[E]	Amino acid transport and metabolism	Molecular Function: transaminase activity (GO:0008483);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K18202|0|pps:100991193|PHYKPL, AGXT2L2; 5-phosphohydroxy-L-lysine phospho-lyase; K18202 5-phosphonooxy-L-lysine phospho-lyase [EC:4.2.3.134] (A)"	Lysine degradation (ko00310)	[R]	General function prediction only	Aminotransferase class-III	5-phosphohydroxy-L-lysine phospho-lyase GN=PHYKPL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: 5-phosphohydroxy-L-lysine phospho-lyase isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000175311(ANKS4B)	--	0	0	0	0	0	0	0.0344689	3	0.033775	2	0.0344061	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Ankyrin repeat and SAM domain-containing protein 4B GN=ANKS4B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	hypothetical protein PANDA_017437 [Ailuropoda melanoleuca]
ENSG00000175318(GRAMD2)	--	0.01661663	1	0	0	0	0	0.016651068	1	0.170175091	0	0.03315439	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	GRAM domain	GRAM domain-containing protein 2 GN=GRAMD2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: GRAM domain-containing protein 2 [Equus caballus]
ENSG00000175322(ZNF519)	--	2.530667726	83	2.52020647	86	4.153811037	133	1.663469656	62	1.919892352	62	2.387445	79	0.917703978	-0.44216819	normal	0.890911353	-0.483436198	normal	0.277468111	-0.748624039	normal	0.15874204	-0.592692225	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:162655|ZNF519, HsT2362; zinc finger protein 519; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain;; BolA-like protein;; Probable zinc-binding domain;; LIM domain"	Zinc finger protein 519 GN=ZNF519 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 420-like isoform X2 [Myotis brandtii]
ENSG00000175324(LSM1)	--	26.60114	470	26.03426	471	27.5573	496	34.84566	619	29.27458	514	32.11805	573	0.802416997	0.365402775	normal	0.965719279	0.104294126	normal	0.948936447	0.199337663	normal	0.324240973	0.226148886	normal	[K]	Transcription	--	"K12620|5.96186e-90|umr:103659125|LSM1; LSM1, U6 small nuclear RNA associated; K12620 U6 snRNA-associated Sm-like protein LSm1 (A)"	RNA degradation (ko03018)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm1 GN=LSM1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	U6 snRNA-associated Sm-like protein LSm1 [Bos taurus] 
ENSG00000175334(BANF1)	--	211.49598	2576	169.58099	2528	177.2788	2486	236.17644	2894	225.65512	2659	188.864224	2281	0.984735719	0.137022933	normal	0.988214382	0.051430756	normal	0.983609239	-0.1323672	normal	0.93492335	0.023718154	normal	--	--	--	--	--	[BL]	"Chromatin structure and dynamics;; Replication, recombination and repair"	Barrier to autointegration factor	"Barrier-to-autointegration factor, N-terminally processed GN=BANF1 OS=Homo sapiens (Human) PE=1 SV=1"	A	RNA processing and modification	PREDICTED: barrier-to-autointegration factor isoform X1 [Physeter catodon]
ENSG00000175344(CHRNA7)	--	2.584021548	71	3.023996531	82	1.99083653	55	1.998322492	64	2.189214839	53	1.67355228	55	0.97047967	-0.176552875	normal	0.775071116	-0.636342369	normal	0.977629683	-0.008069561	normal	0.623059952	-0.296483835	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04809|0|pon:100456533|CHRNA7; cholinergic receptor, nicotinic, alpha 7 (neuronal); K04809 nicotinic acetylcholine receptor alpha-7 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725);; Nicotine addiction (ko05033);; Chemical carcinogenesis (ko05204)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Neuronal acetylcholine receptor subunit alpha-7 (Precursor) GN=CHRNA7 OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: neuronal acetylcholine receptor subunit alpha-7 [Erinaceus europaeus]
ENSG00000175348(TMEM9B)	--	24.032917	631	24.79541908	598	21.63808001	550	32.53821852	793	31.86148305	768	29.4596062	710	0.895828108	0.298199767	normal	0.849676429	0.338776559	normal	0.812629277	0.359224379	normal	0.078650133	0.330569458	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	TMEM9	Transmembrane protein 9B (Precursor) GN=TMEM9B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 9B [Condylura cristata]
ENSG00000175352(NRIP3)	--	0.616617469	40	0.474162323	30	0.5291857	28	2.038004848	132	1.894675862	118	0.775564621	51	1.49E-06	1.654698503	up	1.50E-07	1.902395691	up	0.789780376	0.823379668	normal	0.026375057	1.595068868	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Biological Process: proteolysis (GO:0006508);; 	--	--	[L]	"Replication, recombination and repair"	Aspartyl protease;; Aspartyl protease	Nuclear receptor-interacting protein 3 GN=NRIP3 OS=Homo sapiens (Human) PE=2 SV=1	L	"Replication, recombination and repair"	PREDICTED: nuclear receptor-interacting protein 3 [Vicugna pacos]
ENSG00000175354(PTPN2)	--	13.96392564	534	13.62830948	527	11.2290462	445	10.53380333	405	11.90118946	472	13.85691843	553	0.656887476	-0.42832981	normal	0.952975753	-0.179896837	normal	0.88783762	0.304253457	normal	0.754018971	-0.095251945	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	K18026|0|mcf:101866630|uncharacterized LOC101866630; K18026 tyrosine-protein phosphatase non-receptor type 2 [EC:3.1.3.48] (A)	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase	Tyrosine-protein phosphatase non-receptor type 2 GN=PTPN2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000175356(SCUBE2)	--	0.142876632	11	0.589725951	18	0.048715999	2	0.16371312	11	0.283081333	3	0.16032488	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; GCC2 and GCC3;; Calcium-binding EGF domain;; EGF domain;; EGF-like domain;; CUB domain	"Signal peptide, CUB and EGF-like domain-containing protein 2 (Precursor) GN=SCUBE2 OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: signal peptide, CUB and EGF-like domain-containing protein 2 isoform X1 [Tupaia chinensis]"
ENSG00000175376(EIF1AD)	--	14.4117404	511	13.62735977	570	15.56097134	592	15.15830908	575	18.13587351	637	15.11984745	565	0.962795175	0.139012236	normal	0.963590508	0.13855703	normal	0.970810863	-0.075440462	normal	0.830677142	0.065969449	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	K15025|5.87318e-100|mcf:101866360|EIF1AD; Probable RNA-binding protein EIF1AD; K15025 probable RNA-binding protein EIF1AD (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Translation initiation factor 1A / IF-1	Probable RNA-binding protein EIF1AD GN=EIF1AD OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: probable RNA-binding protein EIF1AD isoform X1 [Mustela putorius furo] 
ENSG00000175387(SMAD2)	--	52.42702652	2535	50.10248426	2251	47.4236128	2251	37.78105952	1941	46.31552101	2313	52.37282106	2419	0.719948955	-0.41572895	normal	0.98765077	0.01776088	normal	0.985918062	0.095491373	normal	0.659975081	-0.097206286	normal	--	--	"Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04500|0|tup:102499541|SMAD2; SMAD family member 2; K04500 mothers against decapentaplegic homolog 2/3 (A)	FoxO signaling pathway (ko04068);; Cell cycle (ko04110);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Adherens junction (ko04520);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Chagas disease (American trypanosomiasis) (ko05142);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Colorectal cancer (ko05210);; Pancreatic cancer (ko05212);; Inflammatory bowel disease (IBD) (ko05321)	[TK]	Signal transduction mechanisms;; Transcription	MH2 domain;; MH1 domain;; Interferon-regulatory factor 3	Mothers against decapentaplegic homolog 2 GN=SMAD2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: mothers against decapentaplegic homolog 2 isoform X1 [Mustela putorius furo] 
ENSG00000175390(EIF3F)	--	396.126767	3901	414.9764141	3638	352.2049502	3538	359.0081951	3520	346.04767	3631	377.5142241	3717	0.984040194	-0.179026559	normal	0.991195999	-0.024195103	normal	0.990822364	0.062886971	normal	0.854463428	-0.04859469	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K03249|0|fca:101083449|EIF3F; eukaryotic translation initiation factor 3, subunit F; K03249 translation initiation factor 3 subunit F (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Maintenance of mitochondrial structure and function	Eukaryotic translation initiation factor 3 subunit F {ECO:0000255|HAMAP-Rule:MF_03005} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit F isoform X1 [Condylura cristata]
ENSG00000175395(ZNF25)	--	3.091233618	235	2.542220736	193	2.516111002	193	2.10087376	167	2.274045603	173	1.62607072	124	0.574757629	-0.519593397	normal	0.952701911	-0.1777831	normal	0.326895921	-0.64024194	normal	0.153054665	-0.442553193	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:219749|ZNF25, KOX19, Zfp9; zinc finger protein 25; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2H2-type zinc finger;; Zinc ribbon domain;; NTF2 fold immunity protein"	Zinc finger protein 25 GN=ZNF25 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 25 [Galeopterus variegatus]
ENSG00000175414(ARL10)	--	0.44490985	2	0.4392099	5	2.0623056	17	1.214898278	19	2.662468	32	1.075091786	20	--	--	--	0.009225023	2.345000149	up	0.988395162	0.209016428	normal	--	--	--	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	"K07958|8.79028e-83|hsa:285598|ARL10, ARL10A; ADP-ribosylation factor-like 10; K07958 ADP-ribosylation factor-like protein 10 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Miro-like protein;; 50S ribosome-binding GTPase;; Signal recognition particle receptor beta subunit;; Ras family;; Gtr1/RagA G protein conserved region	ADP-ribosylation factor-like protein 10 GN=ARL10 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ADP-ribosylation factor-like protein 10 [Camelus ferus]
ENSG00000175416(CLTB)	--	42.04388	971	37.503636	911	42.64751	1051	63.824832	1517	56.447066	1318	44.104703	1040	0.046571166	0.612064984	normal	0.3128358	0.510692368	normal	0.97992914	-0.023436682	normal	0.115734086	0.379735335	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: clathrin coat of trans-Golgi network vesicle (GO:0030130);; Cellular Component: clathrin coat of coated pit (GO:0030132);; 	"K04645|3.12344e-142|mcf:102141474|CLTB; clathrin, light chain B; K04645 clathrin light chain B (A)"	Lysosome (ko04142);; Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016);; Bacterial invasion of epithelial cells (ko05100)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin light chain	Clathrin light chain B GN=CLTB OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: clathrin light chain B isoform 1 [Odobenus rosmarus divergens] 
ENSG00000175426(PCSK1)	--	0.185683727	16	0.138929043	12	0.254239683	21	0.242857111	21	0.305363269	24	0.449299503	39	0.987036632	0.333472637	normal	0.944988294	0.897328041	normal	0.875289079	0.839788684	normal	0.283647559	0.759098041	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01359|0|hsa:5122|PCSK1, BMIQ12, NEC1, PC1, PC3, SPC3; proprotein convertase subtilisin/kexin type 1 (EC:3.4.21.93); K01359 proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Subtilase family;; Proprotein convertase P-domain;; Prohormone convertase enzyme	Neuroendocrine convertase 1 (Precursor) GN=PCSK1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: neuroendocrine convertase 1 [Galeopterus variegatus]
ENSG00000175445(LPL)	--	0	0	0	0	0	0	0	0	0	0	0.016613469	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K01059|0|hsa:4023|LPL, HDLCQ11, LIPD; lipoprotein lipase (EC:3.1.1.34); K01059 lipoprotein lipase [EC:3.1.1.34] (A)"	Glycerolipid metabolism (ko00561);; PPAR signaling pathway (ko03320);; Alzheimer's disease (ko05010)	--	--	Lipase;; PLAT/LH2 domain;; Alpha/beta hydrolase family	Lipoprotein lipase (Precursor) GN=LPL OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	RecName: Full=Lipoprotein lipase; Short=LPL; Flags: Precursor [Neovison vison] 
ENSG00000175449(RFESD)	--	2.018536976	63	1.8172221	44	1.166358695	48	0.839807511	32	1.047943632	28	0.802764645	32	0.408315189	-0.974142734	normal	0.920474579	-0.64546198	normal	0.9342244	-0.571074165	normal	0.157125445	-0.773925255	normal	--	--	"Molecular Function: nitrite reductase [NAD(P)H] activity (GO:0008942);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: nitrate assimilation (GO:0042128);; Molecular Function: 2 iron, 2 sulfur cluster binding (GO:0051537);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	--	--	Rieske-like [2Fe-2S] domain;; Rieske [2Fe-2S] domain	Rieske domain-containing protein GN=RFESD OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: Rieske domain-containing protein [Ceratotherium simum simum]
ENSG00000175455(CCDC14)	--	15.07659905	1727	14.24950124	1575	16.01720297	1943	15.9779226	1899	14.40375193	1724	15.0023986	1805	0.982512728	0.106049568	normal	0.98084257	0.108881441	normal	0.982302176	-0.114486031	normal	0.920619229	0.02841659	normal	--	--	--	K16541|0|hsa:64770|CCDC14; coiled-coil domain containing 14; K16541 coiled-coil domain-containing protein 14 (A)	--	--	--	Coiled-coil domain-containing protein 14	Coiled-coil domain-containing protein 14 GN=CCDC14 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 14 isoform X1 [Tupaia chinensis] 
ENSG00000175463(TBC1D10C)	--	0.039987142	1	0.116768	3	0.151737548	3	0.039793101	1	0.116504033	2	0.079088118	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rab-GTPase-TBC domain	Carabin GN=TBC1D10C OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: carabin isoform X1 [Equus caballus] 
ENSG00000175467(SART1)	--	21.676462	1684	20.93510217	1704	22.04930212	1796	22.36060235	1755	22.211671	1713	19.0227026	1480	0.985196426	0.02872096	normal	0.984950202	-0.013814514	normal	0.929274878	-0.287214763	normal	0.702635969	-0.088782298	normal	--	--	"Biological Process: mRNA splicing, via spliceosome (GO:0000398);; "	K11984|0|pps:100991800|SART1; squamous cell carcinoma antigen recognized by T cells; K11984 U4/U6.U5 tri-snRNP-associated protein 1 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	SART-1 family	U4/U6.U5 tri-snRNP-associated protein 1 GN=SART1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U4/U6.U5 tri-snRNP-associated protein 1 [Tupaia chinensis]
ENSG00000175470(PPP2R2D)	--	5.070030998	629	5.1788089	650	5.131053973	640	5.02729162	625	5.952569	728	5.2247248	643	0.973460485	-0.039938223	normal	0.964850481	0.141760407	normal	0.974500677	-0.001540977	normal	0.911866656	0.035719921	normal	[T]	Signal transduction mechanisms	--	"K04354|0|mcf:102142696|PPP2R2D; protein phosphatase 2, regulatory subunit B, delta; K04354 serine/threonine-protein phosphatase 2A regulatory subunit B (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Dopaminergic synapse (ko04728);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	"WD domain, G-beta repeat"	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform GN=PPP2R2D OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform [Odobenus rosmarus divergens]
ENSG00000175471(MCTP1)	--	15.13613448	545	16.8709857	629	21.15545927	659	26.02140313	595	11.93886783	391	29.43700033	870	0.968852259	0.09554335	normal	0.015543901	-0.705146251	normal	0.74028386	0.391660848	normal	1	-0.001929539	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	C2 domain;; Plant phosphoribosyltransferase C-terminal	Multiple C2 and transmembrane domain-containing protein 1 GN=MCTP1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: multiple C2 and transmembrane domain-containing protein 1 [Loxodonta africana]
ENSG00000175482(POLD4)	--	144.476484	2031	126.1233936	1983	124.6647064	1918	127.864767	1948	152.3428915	2106	114.937173	1805	0.984515263	-0.090958556	normal	0.985609335	0.065345841	normal	0.983527637	-0.095817433	normal	0.887016846	-0.039289422	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; 	"K03505|7.0699e-54|ptr:451366|POLD4; polymerase (DNA-directed), delta 4, accessory subunit; K03505 DNA polymerase delta subunit 4 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; HTLV-I infection (ko05166)	--	--	"DNA polymerase delta, subunit 4"	DNA polymerase delta subunit 4 GN=POLD4 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase delta subunit 4 [Leptonychotes weddellii]
ENSG00000175485(OR52W1)	--	0.0721513	1	0	0	0.0709451	0	0	0	0	0	0.0718937	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:120787|OR52W1, OR11-71, OR52W1P; olfactory receptor, family 52, subfamily W, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 52W1 GN=OR52W1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 52W1-like [Ochotona princeps]
ENSG00000175489(LRRC25)	--	0	0	0.029586674	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Leucine Rich repeats (2 copies)	Leucine-rich repeat-containing protein 25 (Precursor) GN=LRRC25 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 25 isoform X1 [Panthera tigris altaica]
ENSG00000175514(GPR152)	--	0	0	0	0	0.194466	3	0.0504176	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08436|0|hsa:390212|GPR152, PGR5; G protein-coupled receptor 152; K08436 G protein-coupled receptor 152 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 152 GN=GPR152 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 152 [Myotis brandtii]
ENSG00000175518(UBQLNL)	--	0.063278	3	0	0	0.0420524	1	0.0640268	3	0.0205295	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K04523|0|hsa:143630|UBQLNL; ubiquilin-like; K04523 ubiquilin (A)	Protein processing in endoplasmic reticulum (ko04141)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family	Ubiquilin-like protein GN=UBQLNL OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquilin-like protein [Tupaia chinensis] 
ENSG00000175536(LIPT2)	--	3.622758769	44	1.525839939	20	12.22974028	39	3.253102058	44	1.87714219	23	3.006585625	39	0.980662201	-0.029791969	normal	0.986537469	0.168331711	normal	0.981813549	-0.007981931	normal	0.998020245	0.020053898	normal	[H]	Coenzyme transport and metabolism	Biological Process: cellular protein modification process (GO:0006464);; 	K03801|4.73042e-155|hsa:387787|LIPT2; lipoyl(octanoyl) transferase 2 (putative) (EC:2.3.1.181); K03801 lipoyl(octanoyl) transferase [EC:2.3.1.181] (A)	Lipoic acid metabolism (ko00785)	[CH]	Energy production and conversion;; Coenzyme transport and metabolism	Biotin/lipoate A/B protein ligase family	"Putative lipoyltransferase 2, mitochondrial (Precursor) GN=LIPT2 OS=Homo sapiens (Human) PE=3 SV=1"	H	Coenzyme transport and metabolism	"PREDICTED: putative lipoyltransferase 2, mitochondrial [Leptonychotes weddellii]"
ENSG00000175538(KCNE3)	--	0	0	0.085490792	5	0.146382613	1	0.051526035	3	0.142742027	7	0.286691448	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: voltage-gated potassium channel activity (GO:0005249);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	"K04897|1.36966e-71|ptr:466706|KCNE3; potassium voltage-gated channel, Isk-related family, member 3; K04897 potassium voltage-gated channel Isk-related subfamily E member 3 (A)"	Protein digestion and absorption (ko04974)	--	--	Slow voltage-gated potassium channel	Potassium voltage-gated channel subfamily E member 3 GN=KCNE3 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily E member 3 [Orycteropus afer afer]
ENSG00000175544(CABP4)	--	0	0	0	0	0.03462158	1	0	0	0.04083005	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair	Calcium-binding protein 4 GN=CABP4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcium-binding protein 4 [Odobenus rosmarus divergens]
ENSG00000175548(ALG10B)	--	3.201924895	408	4.702621657	450	5.359093585	416	3.448983925	393	3.186200292	359	5.254937863	432	0.966395935	-0.084547659	normal	0.844102794	-0.346062552	normal	0.969346891	0.045992265	normal	0.670679714	-0.126721852	normal	--	--	Molecular Function: dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity (GO:0004583);; Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: dolichol-linked oligosaccharide biosynthetic process (GO:0006488);; 	"K03850|0|hsa:144245|ALG10B, ALG10, KCR1; ALG10B, alpha-1,2-glucosyltransferase (EC:2.4.1.256); K03850 alpha-1,2-glucosyltransferase [EC:2.4.1.256] (A)"	N-Glycan biosynthesis (ko00510)	[OKIT]	"Posttranslational modification, protein turnover, chaperones;; Transcription;; Lipid transport and metabolism;; Signal transduction mechanisms"	DIE2/ALG10 family	"Putative Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase GN=ALG10B OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase [Orcinus orca]"
ENSG00000175550(DRAP1)	--	100.997844	1795	88.27635092	1663	109.690858	2009	104.9927401	1933	91.024354	1601	61.621632	1117	0.984569876	0.075962868	normal	0.982775567	-0.076170816	normal	5.69E-05	-0.854264766	normal	0.46713442	-0.255687513	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	Histone-like transcription factor (CBF/NF-Y) and archaeal histone;; Core histone H2A/H2B/H3/H4	Dr1-associated corepressor GN=DRAP1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: dr1-associated corepressor isoform X1 [Mustela putorius furo]
ENSG00000175556(LONRF3)	--	5.920062348	810	5.855445985	738	6.073369	737	4.436702466	603	5.3982141	660	7.564051	875	0.528275204	-0.455590446	normal	0.956851689	-0.182186322	normal	0.939596269	0.23887659	normal	0.721622195	-0.116073384	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"ATP-dependent protease La (LON) domain;; TPR repeat;; Zinc finger, C3HC4 type (RING finger);; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Tetratricopeptide repeat;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Tetratricopeptide repeat;; RING-type zinc-finger;; Tetratricopeptide repeat"	LON peptidase N-terminal domain and RING finger protein 3 GN=LONRF3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LON peptidase N-terminal domain and RING finger protein 3 isoformX1 [Equus caballus]
ENSG00000175564(UCP3)	--	2.039438	34	0.514575543	26	1.726732	53	0.762342501	34	0.898439949	41	0.6269758	35	0.983738631	-0.029499229	normal	0.940182114	0.607347227	normal	0.918146996	-0.586204118	normal	0.964095232	-0.058694469	normal	--	--	--	"K15103|0|hsa:7352|UCP3, SLC25A9; uncoupling protein 3 (mitochondrial, proton carrier); K15103 solute carrier family 25 (mitochondrial uncoupling protein), member 8/9 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial uncoupling protein 3 GN=UCP3 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	uncoupling protein 3 [Sus scrofa]
ENSG00000175567(UCP2)	--	31.341702	868	19.739325	553	28.52998	815	22.111373	602	29.2798765	801	16.224346	416	0.158095227	-0.557571359	normal	0.332405592	0.511926898	normal	6.85E-06	-0.975924685	normal	0.552643643	-0.319317361	normal	--	--	--	"K15103|0|nle:100607053|UCP2; uncoupling protein 2 (mitochondrial, proton carrier); K15103 solute carrier family 25 (mitochondrial uncoupling protein), member 8/9 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial uncoupling protein 2 GN=UCP2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial uncoupling protein 2 [Ceratotherium simum simum]
ENSG00000175573(C11orf68)	--	22.56936	638	19.92384	575	27.11338	788	24.31448	694	14.63073	410	15.04367	430	0.971157799	0.090338356	normal	0.386131306	-0.507774931	normal	0.000119643	-0.879829048	normal	0.316434747	-0.405826902	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF1917)	UPF0696 protein C11orf68 GN=C11orf68 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0696 protein C11orf68 homolog isoform X1 [Loxodonta africana]
ENSG00000175575(PAAF1)	--	11.8341982	335	9.522529063	281	14.62408348	363	14.05218187	365	12.55925637	337	11.18203362	326	0.964746063	0.09249663	normal	0.931365984	0.239573233	normal	0.954977752	-0.162673513	normal	0.901973769	0.049251171	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11887|0|hsa:80227|PAAF1, PAAF, Rpn14, WDR71; proteasomal ATPase-associated factor 1; K11887 proteasomal ATPase-associated factor 1 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Proteasomal ATPase-associated factor 1 GN=PAAF1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: proteasomal ATPase-associated factor 1 isoform 1 [Orcinus orca]
ENSG00000175581(MRPL48)	--	13.64665023	270	13.14979587	290	13.12450908	269	10.83902454	288	12.7657806	277	12.822577	284	0.965852253	0.06193587	normal	0.963227027	-0.087128527	normal	0.965453668	0.069612401	normal	0.9842288	0.013062439	normal	--	--	--	"K17429|1.87983e-132|hsa:51642|MRPL48, HSPC290, L48MT, MRP-L48; mitochondrial ribosomal protein L48; K17429 large subunit ribosomal protein L48 (A)"	--	[S]	Function unknown	Ribosomal protein S10p/S20e	"39S ribosomal protein L48, mitochondrial (Precursor) GN=MRPL48 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L48, mitochondrial [Ceratotherium simum simum]"
ENSG00000175582(RAB6A)	--	48.59525905	2244	49.36038691	2372	51.0115919	2394	49.71250091	2333	48.43749943	2104	49.01577159	2359	0.98792348	0.025264403	normal	0.974430801	-0.194264261	normal	0.988197127	-0.02952039	normal	0.78854852	-0.06587689	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07893|1.54232e-151|myd:102762716|RAB6A; RAB6A, member RAS oncogene family; K07893 Ras-related protein Rab-6A (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Signal recognition particle receptor beta subunit;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-6A GN=RAB6A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-6A isoform X2 [Myotis lucifugus] 
ENSG00000175591(P2RY2)	--	1.407900693	167	1.939165539	163	2.122360188	160	7.985106	783	7.791911228	861	3.678142098	333	0	2.188118105	up	0	2.369040357	up	6.28E-05	1.042181393	up	0.006683923	1.989366169	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04269|0|ptr:466702|P2RY2; purinergic receptor P2Y, G-protein coupled, 2; K04269 purinergic receptor P2Y, G protein-coupled, 2 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Inflammatory mediator regulation of TRP channels (ko04750)	--	--	7 transmembrane receptor (rhodopsin family)	P2Y purinoceptor 2 GN=P2RY2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: P2Y purinoceptor 2 [Galeopterus variegatus]
ENSG00000175592(FOSL1)	--	21.83564285	657	21.69367833	653	27.17931301	827	38.82476974	1182	22.95190412	688	12.9401113	393	0.000342315	0.814992625	normal	0.973092144	0.053777677	normal	2.58E-07	-1.07872084	down	0.959389613	0.058633181	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04502|5.00219e-100|mcf:102115392|FOSL1; FOS-like antigen 1; K04502 fos-like antigen 1 (A)	Wnt signaling pathway (ko04310);; Osteoclast differentiation (ko04380);; HTLV-I infection (ko05166)	[K]	Transcription	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Fos-related antigen 1 GN=FOSL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: fos-related antigen 1 [Tupaia chinensis]
ENSG00000175595(ERCC4)	--	7.475410205	733	7.440483	660	6.0873922	595	6.383073	595	7.2091089	657	6.002789	560	0.856873998	-0.330984089	normal	0.973790798	-0.027935058	normal	0.969140221	-0.095504029	normal	0.519630456	-0.155281895	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: nuclease activity (GO:0004518);; 	"K10848|0|hsa:2072|ERCC4, ERCC11, FANCQ, RAD1, XPF; excision repair cross-complementation group 4; K10848 DNA excision repair protein ERCC-4 [EC:3.1.-.-] (A)"	Nucleotide excision repair (ko03420);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	ERCC4 domain	DNA repair endonuclease XPF GN=ERCC4 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA repair endonuclease XPF [Trichechus manatus latirostris]
ENSG00000175600(SUGCT)	--	3.508704034	87	3.159401267	82	1.542507433	43	0.865016862	22	1.909498	50	0.7893689	22	3.59E-06	-1.940932174	down	0.659453644	-0.717989914	normal	0.774353553	-0.928672669	normal	0.06645563	-1.19510724	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; 	"K18703|0|hsa:79783|SUGCT, C7orf10, DERP13, ORF19; succinyl-CoA:glutarate-CoA transferase (EC:2.8.3.13); K18703 succinate---hydroxymethylglutarate CoA-transferase [EC:2.8.3.13] (A)"	--	[I]	Lipid transport and metabolism	CoA-transferase family III	Succinate--hydroxymethylglutarate CoA-transferase (Precursor) GN=SUGCT OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: caiB/baiF CoA-transferase family protein C7orf10 homolog isoform X2 [Capra hircus]
ENSG00000175602(CCDC85B)	--	44.5431	975	32.8695	761	41.9513	987	55.8233	1265	50.3058	1106	32.6307	730	0.849061592	0.34435348	normal	0.292420019	0.51709953	normal	0.573186272	-0.44265333	normal	0.730012906	0.165106081	normal	--	--	--	K16758|4.74239e-61|tup:102497936|CCDC85B; coiled-coil domain containing 85B; K16758 coiled-coil domain-containing protein 85B (A)	--	[S]	Function unknown	Uncharacterized conserved proteins (DUF2216)	Coiled-coil domain-containing protein 85B GN=CCDC85B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 85B [Elephantulus edwardii]
ENSG00000175606(TMEM70)	--	39.07448777	499	43.01627763	607	45.89415425	573	45.45520909	619	58.135792	666	45.859129	594	0.909076629	0.279294034	normal	0.967859106	0.112132336	normal	0.972631142	0.043523526	normal	0.576309172	0.141127036	normal	--	--	--	"K17966|5.16197e-145|pps:100994022|TMEM70; transmembrane protein 70; K17966 transmembrane protein 70, mitochondrial (A)"	--	[S]	Function unknown	Protein of unknown function (DUF1301)	"Transmembrane protein 70, mitochondrial (Precursor) GN=TMEM70 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: transmembrane protein 70, mitochondrial [Galeopterus variegatus]"
ENSG00000175634(RPS6KB2)	--	19.22571409	623	17.673838	579	19.468065	645	28.344099	913	30.16045561	943	25.38761095	823	0.273700638	0.519486436	normal	0.016251948	0.680861462	normal	0.841614322	0.342589063	normal	0.001728439	0.515202879	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04688|0|hsa:6199|RPS6KB2, KLS, P70-beta, P70-beta-1, P70-beta-2, S6K-beta2, S6K2, SRK, STK14B, p70(S6K)-beta, p70S6Kb; ribosomal protein S6 kinase, 70kDa, polypeptide 2 (EC:2.7.11.1); K04688 p70 ribosomal S6 kinase [EC:2.7.11.1] (A)"	ErbB signaling pathway (ko04012);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; TGF-beta signaling pathway (ko04350);; Fc gamma R-mediated phagocytosis (ko04666);; Insulin signaling pathway (ko04910);; Proteoglycans in cancer (ko05205);; Acute myeloid leukemia (ko05221);; Choline metabolism in cancer (ko05231)	[RT]	General function prediction only;; Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Protein kinase C terminal domain	Ribosomal protein S6 kinase beta-2 GN=RPS6KB2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ribosomal protein S6 kinase beta-2 [Equus przewalskii]
ENSG00000175643(RMI2)	--	31.166532	625	28.91576289	609	33.24120864	690	27.97482204	565	25.84854753	523	25.76552005	513	0.956507583	-0.175982308	normal	0.933073064	-0.240412893	normal	0.616891551	-0.434819545	normal	0.163058589	-0.286423789	normal	--	--	--	"K15365|2.84809e-100|hsa:116028|RMI2, BLAP18, C16orf75; RecQ mediated genome instability 2; K15365 RecQ-mediated genome instability protein 2 (A)"	Fanconi anemia pathway (ko03460)	--	--	--	RecQ-mediated genome instability protein 2 GN=RMI2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: recQ-mediated genome instability protein 2 [Odobenus rosmarus divergens]
ENSG00000175662(TOM1L2)	--	12.01796715	1262	9.04510013	1042	11.68550934	1247	11.22578876	1299	11.36264853	1183	8.427527532	998	0.982308122	0.010844244	normal	0.968809062	0.161448221	normal	0.872366695	-0.32919396	normal	0.862636741	-0.050918233	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: intracellular protein transport (GO:0006886);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	VHS domain;; GAT domain	TOM1-like protein 2 GN=TOM1L2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TOM1-like protein 2 isoform X2 [Ailuropoda melanoleuca]
ENSG00000175691(ZNF77)	--	0.849706	35	1.0606	44	1.16978	48	0.551588	23	0.754954	31	0.360953	15	0.955818162	-0.603628197	normal	0.951505662	-0.505843312	normal	0.031087528	-1.592031719	normal	0.118944769	-0.901833401	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:58492|ZNF77, pT1; zinc finger protein 77; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain"	Zinc finger protein 77 GN=ZNF77 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 77 [Galeopterus variegatus]
ENSG00000175697(GPR156)	--	0.241718424	22	0.182142672	18	0.169509849	16	0.082942128	6	0.297571759	26	0.115437741	11	0.621418684	-1.66962202	normal	0.977684424	0.475685867	normal	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04617|0|ptr:470896|GPR156, GSK3B; G protein-coupled receptor 156; K04617 gamma-aminobutyric acid type B receptor-like (A)"	Neuroactive ligand-receptor interaction (ko04080)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	7 transmembrane sweet-taste receptor of 3 GCPR	Probable G-protein coupled receptor 156 GN=GPR156 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 156 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000175701(LINC00116)	--	98.43433973	357	105.968322	409	105.784726	413	66.27052159	265	66.52956337	240	63.14462164	239	0.630016003	-0.458464251	normal	0.007376667	-0.786648818	normal	0.005521212	-0.793554514	normal	0.001173128	-0.685609377	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1049)	Uncharacterized protein encoded by LINC00116 GN=LINC00116 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: putative uncharacterized protein encoded by LINC00116-like isoform X1 [Sus scrofa]
ENSG00000175707(KDF1)	--	0	0	0.032236099	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4656)	Keratinocyte differentiation factor 1 GN=KDF1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C1orf172 homolog [Myotis davidii]
ENSG00000175711(B3GNTL1)	--	6.81661	168	3.98923	99	6.096966	154	2.99592	74	2.56863	63	3.112612	78	0.000224019	-1.196729295	down	0.653683155	-0.660740229	normal	0.012483279	-0.975951115	normal	0.006860043	-0.990223212	normal	[M]	Cell wall/membrane/envelope biogenesis	--	--	--	[R]	General function prediction only	Glycosyl transferase family 2;; Glycosyltransferase like family 2;; Glycosyl transferase family 2;; Glycosyltransferase like family 2	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 GN=B3GNTL1 OS=Homo sapiens (Human) PE=2 SV=2"	R	General function prediction only	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 isoform X1 [Myotis brandtii]"
ENSG00000175718(RBMXL3)	--	0.0136467	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12885|0|hsa:139804|RBMXL3, CXorf55; RNA binding motif protein, X-linked-like 3; K12885 heterogeneous nuclear ribonucleoprotein G (A)"	Spliceosome (ko03040)	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	"RNA-binding motif protein, X-linked-like-3 GN=RBMXL3 OS=Homo sapiens (Human) PE=2 SV=2"	K	Transcription	"PREDICTED: RNA-binding motif protein, X chromosome-like [Lipotes vexillifer]"
ENSG00000175727(MLXIP)	--	9.287680939	1482	10.36977231	1580	10.67844488	1493	15.42431868	2440	16.77923664	2623	14.59063031	2217	0.006867158	0.687942334	normal	0.005009874	0.709334446	normal	0.128760444	0.561633364	normal	2.76E-06	0.655024087	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09113|0|hsa:22877|MLXIP, MIR, MONDOA, bHLHe36; MLX interacting protein; K09113 MAX-like protein X (A)"	Non-alcoholic fatty liver disease (NAFLD) (ko04932)	[K]	Transcription	Helix-loop-helix DNA-binding domain	MLX-interacting protein OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: MLX-interacting protein [Ceratotherium simum simum]
ENSG00000175745(NR2F1)	--	6.257370241	341	5.8131402	329	6.41852266	322	5.512204356	258	5.031959857	292	3.86859659	184	0.709599708	-0.430992163	normal	0.946841332	-0.192605347	normal	0.008541389	-0.810544025	normal	0.057687797	-0.4565873	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08547|0|mcf:102120142|NR2F1; nuclear receptor subfamily 2, group F, member 1; K08547 COUP transcription factor 1 (A)"	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	COUP transcription factor 1 GN=NR2F1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: COUP transcription factor 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000175756(AURKAIP1)	--	100.7211	2709	98.558121	2773	100.219332	2625	103.861528	2698	107.016049	2987	106.59249	2942	0.98915927	-0.036681462	normal	0.988027416	0.085777985	normal	0.983144517	0.156103391	normal	0.77952704	0.06871259	normal	--	--	--	"K16830|6.63787e-141|hsa:54998|AURKAIP1, AIP, AKIP, MRP-S38; aurora kinase A interacting protein 1; K16830 aurora kinase A-interacting protein (A)"	--	--	--	Mitochondrial domain of unknown function (DUF1713)	Aurora kinase A-interacting protein GN=AURKAIP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: aurora kinase A-interacting protein [Trichechus manatus latirostris]
ENSG00000175764(TTLL11)	--	1.575979044	60	0.942922574	32	0.903744351	47	2.86322479	112	2.854913719	117	3.264970588	101	0.194876681	0.853403389	normal	7.48E-07	1.801468159	up	0.03406786	1.071273672	normal	0.000996397	1.226103976	up	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16604|0|hsa:158135|TTLL11, C9orf20, bA244O19.1; tubulin tyrosine ligase-like family, member 11; K16604 tubulin polyglutamylase TTLL11 [EC:6.-.-.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin polyglutamylase TTLL11 GN=TTLL11 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: tubulin polyglutamylase TTLL11, partial [Tupaia chinensis]"
ENSG00000175768(TOMM5)	--	125.029226	1325	134.581229	1475	121.851629	1331	170.31301	1865	137.782309	1452	125.467407	1345	0.507426747	0.461897636	normal	0.982794024	-0.044054534	normal	0.982856413	0.006796478	normal	0.573298498	0.152089	normal	--	--	--	K17773|2.42813e-51|pps:100985579|TOMM5; translocase of outer mitochondrial membrane 5 homolog (yeast); K17773 mitochondrial import receptor subunit TOM5 (A)	--	--	--	Mitochondrial import receptor subunit TOM5 homolog	Mitochondrial import receptor subunit TOM5 homolog GN=TOMM5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: mitochondrial import receptor subunit TOM5 homolog [Vicugna pacos]
ENSG00000175782(SLC35E3)	--	15.36226221	610	16.675675	708	14.14136387	569	19.77265455	683	17.18705018	568	18.42414696	668	0.966005721	0.131929934	normal	0.84937369	-0.338475975	normal	0.942449325	0.222581485	normal	0.998020245	0.002631681	normal	--	--	--	"K15285|0|hsa:55508|SLC35E3, BLOV1; solute carrier family 35, member E3; K15285 solute carrier family 35, member E3 (A)"	--	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Triose-phosphate Transporter family;; EamA-like transporter family	Solute carrier family 35 member E3 GN=SLC35E3 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 35 member E3 [Galeopterus variegatus]
ENSG00000175785(PRIMA1)	--	0.198079483	8	0.170161124	13	0.058230873	3	0.044749188	3	0.137539531	9	0.073163132	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Proline-rich membrane anchor 1 (Precursor) GN=PRIMA1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: proline-rich membrane anchor 1 [Orycteropus afer afer]
ENSG00000175787(ZNF169)	--	2.532574697	147	2.276887103	132	2.983097807	176	1.588979071	92	2.468404394	156	1.990856863	123	0.327959091	-0.697635846	normal	0.948825636	0.217289497	normal	0.68049907	-0.519836538	normal	0.423320215	-0.314219602	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:465246|ZNF169; zinc finger protein 169; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Protein of unknown function (FYDLN_acid);; Zn-finger in ubiquitin-hydrolases and other protein"	Zinc finger protein 169 GN=ZNF169 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 169 [Galeopterus variegatus]
ENSG00000175792(RUVBL1)	--	45.2212965	1693	43.29563304	1605	49.006869	1847	47.0411376	1769	42.751494	1589	35.38653042	1320	0.98519685	0.032490966	normal	0.983936923	-0.035846785	normal	0.370318894	-0.4924581	normal	0.425156593	-0.15911226	normal	[K]	Transcription	Molecular Function: DNA helicase activity (GO:0003678);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	K04499|0|umr:103669488|RUVBL1; RuvB-like AAA ATPase 1; K04499 RuvB-like protein 1 (pontin 52) (A)	Wnt signaling pathway (ko04310)	[L]	"Replication, recombination and repair"	TIP49 C-terminus;; Holliday junction DNA helicase ruvB N-terminus;; ATPase family associated with various cellular activities (AAA);; AAA ATPase domain;; AAA domain;; AAA domain (dynein-related subfamily);; Sigma-54 interaction domain	RuvB-like 1 GN=RUVBL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ruvB-like 1 [Myotis lucifugus]
ENSG00000175793(SFN)	--	41.8991	1089	45.1749	1186	48.0361	1284	75.5594	1968	49.8486	1290	44.8639	1173	0.000161827	0.82201959	normal	0.977929793	0.099718557	normal	0.974249142	-0.138562821	normal	0.509389078	0.293439462	normal	--	--	--	K06644|5.60153e-171|ptr:737412|SFN; stratifin; K06644 stratifin (A)	Cell cycle (ko04110);; p53 signaling pathway (ko04115);; Aldosterone-regulated sodium reabsorption (ko04960)	[O]	"Posttranslational modification, protein turnover, chaperones"	14-3-3 protein	14-3-3 protein sigma GN=SFN OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 14-3-3 protein sigma [Vicugna pacos]
ENSG00000175806(MSRA)	--	9.970910666	234	11.02168577	259	12.30450064	224	9.391693224	221	9.543003085	216	13.21602806	269	0.961715283	-0.112533937	normal	0.915652926	-0.2815444	normal	0.929036888	0.254247618	normal	0.927666414	-0.043118141	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: peptide-methionine (S)-S-oxide reductase activity (GO:0008113);; Biological Process: oxidation-reduction process (GO:0055114);; 	K07304|7.42333e-174|mcf:102142280|MSRA; methionine sulfoxide reductase A; K07304 peptide-methionine (S)-S-oxide reductase [EC:1.8.4.11] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptide methionine sulfoxide reductase	Mitochondrial peptide methionine sulfoxide reductase (Precursor) GN=MSRA OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial peptide methionine sulfoxide reductase-like isoform X1 [Panthera tigris altaica] 
ENSG00000175820(CCDC168)	--	0.00186545	1	0	0	0	0	0.00372375	2	0.00360216	1	0.00184708	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 168 GN=CCDC168 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein LOC101399975 [Ceratotherium simum simum]
ENSG00000175826(CTDNEP1)	--	123.5410073	3332	128.6326468	3475	129.6576697	3735	125.678087	3469	132.6692848	3548	141.400586	3731	0.990987124	0.027286845	normal	0.991052801	0.008562786	normal	0.991704446	-0.009833341	normal	0.98564369	0.007111565	normal	[K]	Transcription	--	K17617|1.77947e-167|pps:100988088|CTDNEP1; CTD nuclear envelope phosphatase 1; K17617 CTD nuclear envelope phosphatase 1 [EC:3.1.3.16] (A)	--	[K]	Transcription	NLI interacting factor-like phosphatase	CTD nuclear envelope phosphatase 1 GN=CTDNEP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CTD nuclear envelope phosphatase 1 [Galeopterus variegatus]
ENSG00000175832(ETV4)	--	27.3603293	1117	20.13220456	877	22.12957101	923	12.109096	495	14.434607	609	11.637078	467	8.37E-10	-1.202404076	down	0.205736584	-0.54642371	normal	3.13E-06	-0.988876886	normal	1.26E-06	-0.91411289	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K15592|0|hsa:2118|ETV4, E1A-F, E1AF, PEA3, PEAS3; ets variant 4; K15592 ets translocation variant 4 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	PEA3 subfamily ETS-domain transcription factor N terminal domain;; Ets-domain	ETS translocation variant 4 GN=ETV4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: ETS translocation variant 4 isoform X1 [Tupaia chinensis] 
ENSG00000175854(SWI5)	--	26.969878	313	25.649121	305	29.621415	355	28.087051	337	23.68742	272	23.880392	283	0.965686843	0.075396958	normal	0.948588942	-0.185653728	normal	0.867032668	-0.33371266	normal	0.651112744	-0.146940311	normal	--	--	--	--	--	--	--	Swi5	DNA repair protein SWI5 homolog GN=SWI5 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: DNA repair protein SWI5 homolog [Vicugna pacos]
ENSG00000175866(BAIAP2)	--	27.06075043	794	27.34860312	819	26.57535945	829	30.57555665	890	20.19533654	705	34.24271033	987	0.969351459	0.13358982	normal	0.939291813	-0.237194167	normal	0.939999666	0.242979835	normal	0.845622306	0.059493579	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: plasma membrane organization (GO:0007009);; 	K05627|0|cjc:100413911|BAIAP2; BAI1-associated protein 2; K05627 BAI1-associated protein 2 (A)	Adherens junction (ko04520);; Regulation of actin cytoskeleton (ko04810)	--	--	IRSp53/MIM homology domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Brain-specific angiogenesis inhibitor 1-associated protein 2 GN=BAIAP2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: brain-specific angiogenesis inhibitor 1-associated protein 2 isoform X2 [Elephantulus edwardii]
ENSG00000175868(CALCB)	--	0	0	0.120352025	3	0.092680799	3	0	0	0.172766557	4	0.064643855	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	Calcitonin / CGRP / IAPP family	Calcitonin gene-related peptide 2 (Precursor) GN=CALCB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: calcitonin gene-related peptide 2 [Loxodonta africana]
ENSG00000175874(CREG2)	--	0.838311431	45	0.472592429	28	0.711164548	45	3.03971	172	2.373567	133	2.009811782	110	8.64E-10	1.868618257	up	3.60E-10	2.167593166	up	0.002375178	1.253418448	up	3.65E-07	1.792218513	up	--	--	--	--	--	[K]	Transcription	Pyridoxamine 5'-phosphate oxidase	Protein CREG2 (Precursor) GN=CREG2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein CREG2 [Ochotona princeps]
ENSG00000175877(WBSCR28)	--	0	0	0	0	0	0	0.0939189	1	0.377533	3	0.380457	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Williams-Beuren syndrome chromosomal region 28 protein homologue	Williams-Beuren syndrome chromosomal region 28 protein GN=WBSCR28 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: Williams-Beuren syndrome chromosomal region 28 protein [Galeopterus variegatus]
ENSG00000175879(HOXD8)	--	3.683091477	101	4.444710868	128	4.138770239	111	3.045498193	86	4.33729243	119	2.913885833	85	0.954089932	-0.258511693	normal	0.963168083	-0.125075753	normal	0.913503334	-0.387268852	normal	0.606269728	-0.250630818	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09308|2.19645e-130|ptr:459763|HOXD8; homeobox D8; K09308 homeobox protein HoxB/C/D8 (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-D8 GN=HOXD8 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: homeobox protein Hox-D8 [Sus scrofa]
ENSG00000175893(ZDHHC21)	--	5.255246	656	5.910002164	732	6.290021	760	5.026107	635	4.62576	572	5.575897	697	0.971807408	-0.077586771	normal	0.78332636	-0.376372957	normal	0.967594372	-0.132856055	normal	0.372603931	-0.194777631	normal	[R]	General function prediction only	--	"K18932|0|pps:100983116|ZDHHC21; zinc finger, DHHC-type containing 21; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC21 GN=ZDHHC21 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC21 [Tupaia chinensis]
ENSG00000175894(TSPEAR)	--	0.174809371	9	0.047373436	3	0.2622002	13	0.206312855	12	0.266578301	15	0.140928814	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	EPTP domain	Thrombospondin-type laminin G domain and EAR repeat-containing protein (Precursor) GN=TSPEAR OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	thrombospondin-type laminin G domain and EAR repeat-containing protein precursor [Bos taurus]
ENSG00000175895(PLEKHF2)	--	4.840896195	186	5.787613637	223	4.317024376	164	6.031806228	236	5.32099	205	6.333724841	245	0.904593308	0.310371587	normal	0.957214392	-0.141842723	normal	0.428130395	0.566493102	normal	0.488917353	0.238111792	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	FYVE zinc finger;; PH domain	Pleckstrin homology domain-containing family F member 2 GN=PLEKHF2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family F member 2 [Camelus ferus] 
ENSG00000175899(A2M)	--	0.0100598	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	"K03910|0|hsa:2|A2M, A2MD, CPAMD5, FWP007, S863-7; alpha-2-macroglobulin; K03910 alpha-2-macroglobulin (A)"	Complement and coagulation cascades (ko04610)	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; Alpha-2-macroglobulin family N-terminal region;; Alpha-2-macroglobulin family;; A-macroglobulin receptor;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region;; Prenyltransferase-like;; Seminal vesicle autoantigen (SVA)	Alpha-2-macroglobulin (Precursor) GN=A2M OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: alpha-2-macroglobulin [Pteropus alecto]
ENSG00000175906(ARL4D)	--	8.32732	232	6.16762	177	8.29286	237	11.6636	327	12.2694	337	7.4256	207	0.645279918	0.461746902	normal	0.001485403	0.901896872	normal	0.947202258	-0.202166276	normal	0.289195556	0.409134373	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07945|9.43981e-135|ptr:454713|ARL4D; ADP-ribosylation factor-like 4D; K07945 ADP-ribosylation factor-like protein 4 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Miro-like protein;; Signal recognition particle receptor beta subunit;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase;; Gtr1/RagA G protein conserved region	ADP-ribosylation factor-like protein 4D GN=ARL4D OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like 4D [Canis lupus familiaris] 
ENSG00000175920(DOK7)	--	0.147317306	6	0.332837736	14	0.046421176	1	0.122828568	5	0.095433384	3	0.145115316	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	--	--	--	--	PTB domain (IRS-1 type)	Protein Dok-7 GN=DOK7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein Dok-7 isoform X2 [Mustela putorius furo]
ENSG00000175928(LRRN1)	--	0.0471596	3	0	0	0.0472243	2	0.0157313	1	0.0151611	0	0.108789	7	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Immunoglobulin I-set domain;; Leucine Rich Repeat;; Leucine rich repeat;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Leucine-rich repeat;; Immunoglobulin domain;; Leucine Rich repeat;; Immunoglobulin domain	Leucine-rich repeat neuronal protein 1 (Precursor) GN=LRRN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat neuronal protein 1 [Equus przewalskii] 
ENSG00000175931(UBE2O)	--	12.79458316	1528	15.050655	1885	14.5573219	1762	13.013642	1594	12.738523	1526	14.220807	1736	0.984182623	0.030145145	normal	0.897186196	-0.325944875	normal	0.985374942	-0.029712726	normal	0.60106109	-0.112735574	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K10581|0|hsa:63893|UBE2O, E2-230K; ubiquitin-conjugating enzyme E2O (EC:6.3.2.19); K10581 ubiquitin-conjugating enzyme E2 O [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	E2/E3 hybrid ubiquitin-protein ligase UBE2O GN=UBE2O OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 O [Canis lupus familiaris]
ENSG00000175946(KLHL38)	--	0.0771361	3	0	0	0.0747569	2	0.0252969	1	0.0751216	2	0.202986	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13959|0|hsa:340359|KLHL38, C8ORFK36; kelch-like family member 38; K13959 kelch-like protein 38 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; BTB/POZ domain;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Kelch-like protein 38 GN=KLHL38 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 38 [Ceratotherium simum simum]
ENSG00000175970(UNC119B)	--	16.3926	1243	15.5746	1210	15.0223	1150	17.5781	1343	18.6118	1398	18.2237	1378	0.980176799	0.080704764	normal	0.966490991	0.186713507	normal	0.943076694	0.252347048	normal	0.381453204	0.171894165	normal	--	--	--	--	--	[UT]	"Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	"GMP-PDE, delta subunit"	Protein unc-119 homolog B GN=UNC119B OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein unc-119 homolog B [Odobenus rosmarus divergens]
ENSG00000175984(DENND2C)	--	0.537333453	59	0.377082548	36	0.485289313	46	0.217642889	22	0.264754625	29	0.201083119	22	0.034463861	-1.39234118	normal	0.976022344	-0.318436598	normal	0.621611713	-1.022778586	normal	0.075444683	-0.9707226	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; uDENN domain;; dDENN domain	DENN domain-containing protein 2C GN=DENND2C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 2C isoform X4 [Equus caballus]
ENSG00000175985(PLEKHD1)	--	0.0383802	4	0	0	0.00928871	0	0.0191883	2	0.0187597	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PH domain	Pleckstrin homology domain-containing family D member 1 GN=PLEKHD1 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family D member 1 [Camelus ferus]
ENSG00000176009(ASCL3)	--	0.162066	1	0	0	0.314124	1	0.311545	2	0.470502	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09067|1.70484e-130|hsa:56676|ASCL3, HASH3, SGN1, bHLHa42; achaete-scute family bHLH transcription factor 3; K09067 achaete-scute complex protein (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Achaete-scute homolog 3 GN=ASCL3 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: achaete-scute homolog 3 [Leptonychotes weddellii]
ENSG00000176014(TUBB6)	--	52.586244	1711	53.89416317	1713	57.0429569	1750	73.24141202	2452	66.25405603	2109	53.28084851	1754	0.407794992	0.487919223	normal	0.941279633	0.278385553	normal	0.985632098	-0.004993306	normal	0.200006351	0.265345176	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07375|0|ptr:455508|TUBB6; tubulin, beta 6 class V; K07375 tubulin beta (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta-6 chain GN=TUBB6 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin beta-5 chain-like [Ochotona princeps]
ENSG00000176018(LYSMD3)	--	6.79820528	405	9.182452	524	9.305526	497	8.271859	500	9.354775816	558	9.836521353	589	0.91325985	0.27224305	normal	0.969740344	0.069078544	normal	0.93499872	0.236069766	normal	0.447272937	0.187259312	normal	--	--	--	--	--	[R]	General function prediction only	LysM domain	LysM and putative peptidoglycan-binding domain-containing protein 3 GN=LYSMD3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lysM and putative peptidoglycan-binding domain-containing protein 3 [Trichechus manatus latirostris]
ENSG00000176022(B3GALT6)	--	19.4324	822	15.8898	692	16.4883	722	17.5634	750	18.4293	782	19.6723	838	0.963394607	-0.162761409	normal	0.963591398	0.154651937	normal	0.952057708	0.206258614	normal	0.824780737	0.063067637	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K00734|2.05895e-159|hsa:126792|B3GALT6, EDSP2, SEMDJL1, beta3GalT6; UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6 (EC:2.4.1.134); K00734 galactosylxylosylprotein 3-beta-galactosyltransferase [EC:2.4.1.134] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532);; Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"Beta-1,3-galactosyltransferase 6 GN=B3GALT6 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyltransferase 6 [Odobenus rosmarus divergens]"
ENSG00000176024(ZNF613)	--	1.60351626	98	1.526615094	66	1.752834	77	1.930148346	94	1.333983034	83	1.468218127	94	0.969688768	-0.089520029	normal	0.952115866	0.303016129	normal	0.953919694	0.274621936	normal	0.813067828	0.147986749	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:79898|ZNF613; zinc finger protein 613; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 613 GN=ZNF613 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 613 [Galeopterus variegatus]
ENSG00000176029(C11orf16)	--	0.06694	2	0.0325993	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4537)	Uncharacterized protein C11orf16 GN=C11orf16 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C11orf16 homolog [Pteropus alecto]
ENSG00000176040(TMPRSS7)	--	0.04860393	2	0.025143513	1	0.02494112	0	0.024259	1	0.024559904	0	0.100105433	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; 	"K09638|0|myb:102262503|TMPRSS7; transmembrane protease, serine 7; K09638 transmembrane protease, serine 7 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; SEA domain;; Low-density lipoprotein receptor domain class A;; CUB domain	Transmembrane protease serine 7 GN=TMPRSS7 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 7 [Myotis brandtii]
ENSG00000176046(NUPR1)	--	1.259122071	33	1.7603366	121	0.275029068	36	0.303157048	40	1.146742121	37	7.464510039	302	0.97902755	0.236681753	normal	2.02E-06	-1.690409355	down	0	3.008216097	up	0.733877458	0.979361646	normal	--	--	--	"K15626|9.52792e-41|hsa:26471|NUPR1, COM1, P8; nuclear protein, transcriptional regulator, 1; K15626 nuclear protein, 1 (A)"	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	DNA-binding nuclear phosphoprotein p8	Nuclear protein 1 GN=NUPR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: nuclear protein 1 [Vicugna pacos]
ENSG00000176049(JAKMIP2)	--	0.136568993	12	0.040721265	3	0.038100008	4	0.005864331	1	0	0	0.01347965	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Janus kinase and microtubule-interacting protein 2 GN=JAKMIP2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: janus kinase and microtubule-interacting protein 2 isoform X2 [Orycteropus afer afer]
ENSG00000176055(MBLAC2)	--	3.582015	198	3.347882	188	3.724817	201	3.467947	184	2.217914	120	3.797742	209	0.95982755	-0.135535554	normal	0.285758977	-0.662396914	normal	0.966143449	0.047664297	normal	0.5711589	-0.215278305	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Metallo-beta-lactamase superfamily;; Beta-lactamase superfamily domain	Metallo-beta-lactamase domain-containing protein 2 GN=MBLAC2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: metallo-beta-lactamase domain-containing protein 2 [Condylura cristata] 
ENSG00000176058(TPRN)	--	4.731561	235	5.221046	267	4.0097932	209	6.176077	310	4.6139624	232	5.3505514	271	0.837404413	0.366682309	normal	0.939051516	-0.22278648	normal	0.85078514	0.364178182	normal	0.612159422	0.171328514	normal	--	--	Molecular Function: phosphatase binding (GO:0019902);; 	--	--	--	--	"Phostensin PP1-binding and SH3-binding region;; PP1-regulatory protein, Phostensin N-terminal"	Taperin GN=TPRN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: taperin [Galeopterus variegatus]
ENSG00000176076(KCNE5)	--	0.0899375	2	0.0442967	1	0.257839	5	0.44352	10	0.216117	4	0.39506	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: voltage-gated potassium channel activity (GO:0005249);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	"K04895|1.44628e-62|hsa:23630|KCNE1L, KCNE5; KCNE1-like; K04895 potassium voltage-gated channel Isk-related subfamily E member 1-like (A)"	--	--	--	Slow voltage-gated potassium channel	Potassium voltage-gated channel subfamily E member 1-like protein GN=KCNE1L OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily E member 1-like protein [Ochotona princeps]
ENSG00000176087(SLC35A4)	--	44.221551	1968	53.682061	2111	52.852429	2179	52.256983	2039	52.406221	2079	54.075911	2286	0.986784911	0.020283734	normal	0.986485251	-0.043432025	normal	0.986944499	0.060826547	normal	0.971889593	0.01252642	normal	--	--	Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15273|6.58474e-110|ptr:471650|SLC35A4; solute carrier family 35, member A4; K15273 solute carrier family 35 (probable UDP-sugar transporter), member A4 (A)"	--	[G]	Carbohydrate transport and metabolism	Nucleotide-sugar transporter;; EamA-like transporter family	Probable UDP-sugar transporter protein SLC35A4 GN=SLC35A4 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: probable UDP-sugar transporter protein SLC35A4 [Vicugna pacos]
ENSG00000176092(AIM1L)	--	0.245515085	13	0.202432064	11	0.072303603	3	0.07630978	9	0.22065117	14	0.14540293	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Beta/Gamma crystallin;; Ricin-type beta-trefoil lectin domain	Absent in melanoma 1-like protein GN=AIM1L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC103014091 [Balaenoptera acutorostrata scammoni]
ENSG00000176095(IP6K1)	--	9.099461995	704	10.58496848	768	9.478301459	734	10.44907906	809	12.7317654	981	10.9068289	853	0.961390563	0.169386969	normal	0.865053957	0.331142071	normal	0.951743455	0.208076213	normal	0.219688605	0.239773253	normal	--	--	"Molecular Function: inositol-1,4,5-trisphosphate 3-kinase activity (GO:0008440);; "	"K07756|0|ptr:460379|IP6K1, IHPK1; inositol hexakisphosphate kinase 1; K07756 inositol-hexakisphosphate kinase [EC:2.7.4.21] (A)"	--	[KIT]	Transcription;; Lipid transport and metabolism;; Signal transduction mechanisms	Inositol polyphosphate kinase	Inositol hexakisphosphate kinase 1 GN=IP6K1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: inositol hexakisphosphate kinase 1 isoformX2 [Canis lupus familiaris]
ENSG00000176101(SSNA1)	--	66.00912	1201	69.61242	1322	70.57439	1340	70.96275	1293	70.59846	1242	72.67893	1300	0.98003854	0.07556069	normal	0.97741402	-0.111352113	normal	0.981830452	-0.051953288	normal	0.910957211	-0.031594776	normal	--	--	--	K16780|8.60753e-79|pps:100990725|SSNA1; Sjogren syndrome nuclear autoantigen 1; K16780 sjoegren syndrome nuclear autoantigen 1 (A)	--	--	--	--	Sjoegren syndrome nuclear autoantigen 1 GN=SSNA1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Sjoegren syndrome nuclear autoantigen 1 homolog [Vicugna pacos] 
ENSG00000176102(CSTF3)	--	27.571977	1039	30.273749	1115	30.72261901	1077	39.81393893	1555	29.01814838	1054	27.40272104	1120	0.156067445	0.55021756	normal	0.975972354	-0.102452453	normal	0.979854725	0.048122775	normal	0.573699711	0.184425356	normal	[A]	RNA processing and modification	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: mRNA processing (GO:0006397);; 	"K14408|0|ssc:100622040|CSTF3; cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa; K14408 cleavage stimulation factor subunit 3 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Suppressor of forked protein (Suf);; Tetratricopeptide repeat	Cleavage stimulation factor subunit 3 GN=CSTF3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: cleavage stimulation factor subunit 3 [Pantholops hodgsonii]
ENSG00000176105(YES1)	--	19.28299441	1395	18.7739565	1375	19.20424425	1368	18.906497	1381	18.20817578	1324	15.62314134	1136	0.982563562	-0.045333883	normal	0.980585593	-0.075870009	normal	0.92867145	-0.276061433	normal	0.546251926	-0.129214605	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05705|0|ptr:455322|YES1; YES proto-oncogene 1, Src family tyrosine kinase; K05705 tyrosine-protein kinase Yes [EC:2.7.10.2] (A)"	Adherens junction (ko04520);; Tight junction (ko04530)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Tyrosine-protein kinase Yes GN=YES1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase Yes isoform X2 [Equus caballus]
ENSG00000176108(CHMP6)	--	16.39912139	669	15.71929289	717	16.04260654	705	16.78621495	748	19.1820726	795	15.87132161	734	0.967492965	0.129917534	normal	0.968265488	0.127300119	normal	0.974768799	0.049760747	normal	0.691950546	0.101752067	normal	--	--	Biological Process: vacuolar transport (GO:0007034);; 	"K12195|3.71728e-72|hsa:79643|CHMP6, VPS20; charged multivesicular body protein 6; K12195 charged multivesicular body protein 6 (A)"	Endocytosis (ko04144)	[R]	General function prediction only	Snf7	Charged multivesicular body protein 6 GN=CHMP6 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 6 [Balaenoptera acutorostrata scammoni]
ENSG00000176124(DLEU1)	--	7.67952	169	6.57847	135	10.31855	210	5.676	124	5.838434	110	6.35482	143	0.77510508	-0.472478427	normal	0.927462983	-0.312990712	normal	0.516903435	-0.557767724	normal	0.164452913	-0.467371929	normal	--	--	--	--	--	--	--	--	Leukemia-associated protein 1 GN=DLEU1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	--
ENSG00000176125(UFSP1)	--	6.93532	91	3.75082	52	5.88293	83	5.09863	69	5.13328	68	2.89229	39	0.916684479	-0.421893166	normal	0.951889516	0.356507088	normal	0.087030935	-1.068864054	normal	0.494722325	-0.38299445	normal	--	--	--	--	--	[S]	Function unknown	Peptidase family C78	Inactive Ufm1-specific protease 1 GN=UFSP1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: inactive Ufm1-specific protease 1 [Orcinus orca]
ENSG00000176142(TMEM39A)	--	11.96856518	455	16.79295748	548	12.73519729	417	14.13991123	478	15.65927511	579	15.34479901	675	0.970332971	0.040179436	normal	0.970857263	0.057805697	normal	0.018870454	0.684578962	normal	0.38504904	0.266047151	normal	--	--	--	--	--	[S]	Function unknown	Putative transmembrane protein	Transmembrane protein 39A GN=TMEM39A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 39A [Orycteropus afer afer]
ENSG00000176148(TCP11L1)	--	12.27213096	933	12.84930291	896	15.48246846	1012	15.563575	1222	20.79466809	1465	16.34001972	1387	0.823461489	0.35794667	normal	0.010279373	0.686988103	normal	0.563327956	0.445895623	normal	0.000969811	0.499485057	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	T-complex protein 11	T-complex protein 11-like protein 1 GN=TCP11L1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: T-complex protein 11-like protein 1 [Galeopterus variegatus]
ENSG00000176153(GPX2)	--	2.379808	36	2.83302	41	1.70801	27	31.79356	471	56.236799	824	59.162637	891	0	3.623909445	up	0	4.258312024	up	0	4.96015177	up	5.07E-12	4.37368726	up	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K00432|1.14951e-137|ptr:467483|GPX2; glutathione peroxidase 2 (gastrointestinal) (EC:1.11.1.9); K00432 glutathione peroxidase [EC:1.11.1.9] (A)	Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590);; Thyroid hormone synthesis (ko04918)	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Glutathione peroxidase 2 GN=GPX2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: glutathione peroxidase 2 [Tupaia chinensis]
ENSG00000176155(CCDC57)	--	5.972973932	1088	5.456961207	1008	5.359093231	1093	5.146798892	943	5.401128639	964	5.469629115	1013	0.945118105	-0.236821527	normal	0.976045822	-0.085685675	normal	0.97456632	-0.117781346	normal	0.48846016	-0.148016167	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 57 GN=CCDC57 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	Coiled-coil domain-containing protein 57 [Bos mutus]
ENSG00000176160(HSF5)	--	0	0	0	0	0	0	0.0153627	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	--	--	HSF-type DNA-binding	Heat shock factor protein 5 GN=HSF5 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: heat shock factor protein 5 [Odobenus rosmarus divergens]
ENSG00000176165(FOXG1)	--	0.184727	14	0.130558	10	0.165598	12	0.104945	8	0.164781	12	0.12952	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09385|0|amj:102576222|forkhead box protein G1-like; K09385 forkhead box protein G (A)	FoxO signaling pathway (ko04068)	[K]	Transcription	Fork head domain	Forkhead box protein G1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: uncharacterized protein LOC101645050 [Echinops telfairi]
ENSG00000176170(SPHK1)	--	5.2956403	151	4.187746	129	4.583047012	138	11.04845984	280	12.331296	305	7.815486022	219	0.006766404	0.85357471	normal	2.94E-06	1.210509692	up	0.240683369	0.652248781	normal	0.000185284	0.921922914	normal	[IR]	Lipid transport and metabolism;; General function prediction only	Molecular Function: kinase activity (GO:0016301);; 	K04718|0|ptr:738821|SPHK1; sphingosine kinase 1; K04718 sphingosine kinase [EC:2.7.1.91] (A)	Sphingolipid metabolism (ko00600);; Calcium signaling pathway (ko04020);; Sphingolipid signaling pathway (ko04071);; VEGF signaling pathway (ko04370);; Fc gamma R-mediated phagocytosis (ko04666);; Tuberculosis (ko05152)	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase catalytic domain	Sphingosine kinase 1 GN=SPHK1 OS=Homo sapiens (Human) PE=1 SV=1	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: sphingosine kinase 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000176171(BNIP3)	--	61.72201061	2510	63.51812189	2418	59.40368972	2326	70.71385984	2815	35.63975344	1419	50.92721601	2058	0.984648291	0.134537504	normal	0.00051925	-0.78971341	normal	0.975956829	-0.184771755	normal	0.614117709	-0.227881717	normal	--	--	Cellular Component: mitochondrial envelope (GO:0005740);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: positive regulation of apoptotic process (GO:0043065);; 	K15464|6.02516e-134|ptr:450831|BNIP3; BCL2/adenovirus E1B 19kDa interacting protein 3; K15464 BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (A)	FoxO signaling pathway (ko04068);; Legionellosis (ko05134)	--	--	BNIP3	BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 GN=BNIP3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like [Tupaia chinensis]
ENSG00000176182(MYPOP)	--	10.66601	358	10.82792	359	10.95954	377	10.25051	337	10.793502	354	9.56788	321	0.962057304	-0.117523276	normal	0.96721455	-0.041485054	normal	0.931876379	-0.239241446	normal	0.671306451	-0.133605846	normal	--	--	--	--	--	--	--	Myb/SANT-like DNA-binding domain	"Myb-related transcription factor, partner of profilin GN=MYPOP OS=Homo sapiens (Human) PE=2 SV=2"	K	Transcription	"PREDICTED: myb-related transcription factor, partner of profilin, partial [Mustela putorius furo]"
ENSG00000176208(ATAD5)	--	5.884547116	817	6.344054924	860	6.403198491	832	4.963562471	711	5.71208376	802	5.018036222	681	0.942046787	-0.230852923	normal	0.970286442	-0.121938876	normal	0.898854012	-0.296623182	normal	0.290252958	-0.214811419	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	--	--	[L]	"Replication, recombination and repair"	ATPase family associated with various cellular activities (AAA)	ATPase family AAA domain-containing protein 5 GN=ATAD5 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ATPase family AAA domain-containing protein 5 [Ceratotherium simum simum]
ENSG00000176209(SMIM19)	--	17.09292943	249	18.003044	233	14.71667312	236	16.6231259	227	14.5440519	215	21.06154718	303	0.954746296	-0.163230297	normal	0.957792714	-0.136497256	normal	0.858053461	0.350253834	normal	0.951909417	0.032883322	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0697	Small integral membrane protein 19 GN=SMIM19 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: small integral membrane protein 19 [Elephantulus edwardii]
ENSG00000176222(ZNF404)	--	2.2029253	54	1.960449151	61	1.127452	24	0.761885903	32	2.001261	44	2.06856901	58	0.819801636	-0.757404089	normal	0.931854713	-0.478695106	normal	0.148834977	1.214054944	normal	0.955958996	-0.073595113	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:342908|ZNF404; zinc finger protein 404; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 404 GN=ZNF404 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 404 [Odobenus rosmarus divergens]
ENSG00000176225(RTTN)	--	7.910813067	1018	7.348310774	884	7.678714808	987	4.512966277	589	4.4259273	568	4.291218796	544	0.000362816	-0.818584232	normal	0.027315865	-0.658165169	normal	0.000106307	-0.865920812	normal	3.37E-07	-0.785516727	normal	--	--	--	K16484|0|hsa:25914|RTTN; rotatin; K16484 rotatin (A)	--	--	--	"Rotatin, an armadillo repeat protein, centriole functioning"	Rotatin GN=RTTN OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: rotatin [Ceratotherium simum simum]
ENSG00000176244(ACBD7)	--	1.214944	59	0.930227311	42	0.874124662	46	1.98495049	101	1.822708077	96	1.639338	83	0.521692932	0.730050615	normal	0.021720307	1.143273077	normal	0.466860543	0.822775134	normal	0.027319213	0.90776651	normal	[I]	Lipid transport and metabolism	--	--	--	[I]	Lipid transport and metabolism	Acyl CoA binding protein	Acyl-CoA-binding domain-containing protein 7 GN=ACBD7 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-CoA-binding domain-containing protein 7 [Eptesicus fuscus]
ENSG00000176248(ANAPC2)	--	17.85244	875	18.78357	969	18.86817	958	19.02116	947	20.32581	982	17.84711	896	0.975654847	0.083108854	normal	0.978790777	-0.002196793	normal	0.974191074	-0.104647514	normal	0.981777552	-0.009476316	normal	--	--	Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Molecular Function: ubiquitin protein ligase binding (GO:0031625);; 	"K03349|0|hsa:29882|ANAPC2, APC2; anaphase promoting complex subunit 2; K03349 anaphase-promoting complex subunit 2 (A)"	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	Cullin family;; Anaphase promoting complex (APC) subunit 2	Anaphase-promoting complex subunit 2 GN=ANAPC2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anaphase-promoting complex subunit 2 [Galeopterus variegatus]
ENSG00000176261(ZBTB8OS)	--	16.780388	226	17.263694	257	11.899255	187	11.890662	214	12.360739	173	13.978839	218	0.962136438	-0.108784072	normal	0.346126005	-0.588175278	normal	0.945988375	0.211413511	normal	0.653176852	-0.168921815	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Archease protein family (MTH1598/TM1083)	Protein archease GN=ZBTB8OS OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein archease [Pteropus alecto] 
ENSG00000176273(SLC35G1)	--	7.430491625	263	9.296877967	310	7.158787203	259	7.11664	270	6.933542	242	5.777212816	197	0.967306486	0.007023848	normal	0.823262998	-0.376602514	normal	0.808505125	-0.400358903	normal	0.402534623	-0.253121685	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	EamA-like transporter family	Solute carrier family 35 member G1 GN=SLC35G1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: solute carrier family 35 member G1 [Oryctolagus cuniculus]
ENSG00000176358(TAC4)	--	0	0	0	0	0	0	0	0	0	0	0.284773	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05241|3.43853e-58|pon:100457842|TAC4; tachykinin 4 (hemokinin); K05241 tachykinin 4 (A)	--	--	--	--	Endokinin-C (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: tachykinin-4 isoform X1 [Galeopterus variegatus]
ENSG00000176371(ZSCAN2)	--	9.350465083	288	10.27445483	296	8.868551092	260	6.41713428	242	9.320281624	285	6.843040052	306	0.91462212	-0.280260439	normal	0.964181258	-0.075667797	normal	0.938336266	0.225518242	normal	0.928754815	-0.039596773	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09230|0|ptr:453604|ZSCAN2; zinc finger and SCAN domain containing 2; K09230 SCAN domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; SCAN domain;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; TFIIH C1-like domain;; BED zinc finger"	Zinc finger and SCAN domain-containing protein 2 GN=ZSCAN2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 2 [Orycteropus afer afer]
ENSG00000176381(PRR18)	--	0.0445859	2	0.143629061	1	0	0	0.088448433	4	0.422846	12	0.0436526	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Proline-rich protein 18 GN=PRR18 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: proline-rich protein 18 [Orcinus orca]
ENSG00000176383(B3GNT4)	--	0.816709	23	0.629048465	26	0.349081	20	0.49801	25	0.449678297	18	0.260926198	13	0.987235526	0.084074398	normal	0.975287462	-0.515700609	normal	0.981534541	-0.575453989	normal	0.733747202	-0.324723877	normal	--	--	"Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K07971|0|hsa:79369|B3GNT4, B3GN-T4, beta3Gn-T4; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4; K07971 beta-1,3-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase;; Fringe-like	"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 GN=B3GNT4 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 isoform X1 [Myotis davidii] "
ENSG00000176386(CDC26)	--	19.9807	287	23.1	342	20.5594	305	27.5182	415	30.0436	430	29.446	437	0.473080061	0.49899581	normal	0.88720757	0.307698085	normal	0.426945463	0.508415667	normal	0.047347167	0.435787509	normal	--	--	--	K03359|4.94425e-42|ptr:473026|CDC26; cell division cycle 26; K03359 anaphase-promoting complex subunit 12 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	--	--	Anaphase-promoting complex APC subunit 1	Anaphase-promoting complex subunit CDC26 GN=CDC26 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anaphase-promoting complex subunit CDC26 [Galeopterus variegatus] 
ENSG00000176387(HSD11B2)	--	0.798094	23	0.541791232	15	0.724649	20	0.520109	15	0.4945753	14	0.592881	17	0.977058722	-0.597711125	normal	--	--	--	0.988216208	-0.224339101	normal	--	--	--	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K00071|0|hsa:3291|HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3; hydroxysteroid (11-beta) dehydrogenase 2 (EC:1.1.1.146); K00071 corticosteroid 11-beta-dehydrogenase isozyme 2 [EC:1.1.1.-] (A)"	Steroid hormone biosynthesis (ko00140);; Aldosterone-regulated sodium reabsorption (ko04960)	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase	Corticosteroid 11-beta-dehydrogenase isozyme 2 GN=HSD11B2 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: corticosteroid 11-beta-dehydrogenase isozyme 2 [Odobenus rosmarus divergens]
ENSG00000176390(CRLF3)	--	10.8364	518	11.0606	538	10.8276	518	9.592115	461	7.464731	352	7.66996	367	0.948119925	-0.198393364	normal	0.077909098	-0.631246152	normal	0.405454938	-0.503707507	normal	0.029917469	-0.437684257	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	--	Cytokine receptor-like factor 3 GN=CRLF3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: cytokine receptor-like factor 3 [Leptonychotes weddellii]
ENSG00000176393(RNPEP)	--	60.50967886	2556	59.11852	2454	57.8087979	2442	48.042129	2003	51.26427198	2170	54.624019	2294	0.815442306	-0.382297332	normal	0.974118216	-0.198736424	normal	0.985901971	-0.09842635	normal	0.198617048	-0.225335024	normal	[E]	Amino acid transport and metabolism	Molecular Function: metallopeptidase activity (GO:0008237);; Molecular Function: zinc ion binding (GO:0008270);; 	K01260|0|hsa:6051|RNPEP; arginyl aminopeptidase (aminopeptidase B) (EC:3.4.11.6); K01260 aminopeptidase B [EC:3.4.11.6] (A)	--	[IOVE]	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms;; Amino acid transport and metabolism"	"Peptidase family M1;; Leukotriene A4 hydrolase, C-terminal;; Peptidase MA superfamily"	Aminopeptidase B GN=RNPEP OS=Homo sapiens (Human) PE=1 SV=2	EIOV	"Amino acid transport and metabolism;; Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Defense mechanisms"	PREDICTED: LOW QUALITY PROTEIN: aminopeptidase B [Dasypus novemcinctus]
ENSG00000176396(EID2)	--	25.3229	678	21.8034	608	23.5829	656	29.7945	816	31.7806	856	24.2672	658	0.939296079	0.23596367	normal	0.485463774	0.471120954	normal	0.97476378	-0.003890717	normal	0.231513712	0.24111538	normal	--	--	--	--	--	--	--	--	EP300-interacting inhibitor of differentiation 2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: EP300-interacting inhibitor of differentiation 2 [Galeopterus variegatus]
ENSG00000176399(DMRTA1)	--	1.196398114	96	1.43327541	116	1.115909	89	0.849942	65	0.927032	70	1.354034885	110	0.788734523	-0.582029831	normal	0.388922489	-0.737610687	normal	0.944744199	0.29285117	normal	0.516550292	-0.31693518	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	DM DNA binding domain;; DMRTA motif	Doublesex- and mab-3-related transcription factor A1 GN=DMRTA1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: doublesex- and mab-3-related transcription factor A1 [Condylura cristata]
ENSG00000176401(EID2B)	--	4.65359	138	4.90645	148	4.88674	146	4.98441	151	5.5831	166	4.95111	148	0.965107653	0.09800473	normal	0.959078209	0.142781388	normal	0.967902886	0.011221915	normal	0.87495885	0.085031385	normal	--	--	--	--	--	--	--	--	EP300-interacting inhibitor of differentiation 2B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: EP300-interacting inhibitor of differentiation 2B [Oryctolagus cuniculus]
ENSG00000176402(GJC3)	--	0.116603	2	0.169091	3	0.222832	3	0.281906	5	0.22747	3	0.114364	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07628|3.66159e-160|hsa:349149|GJC3, CX29, CX30.2, CX31.3, GJE1; gap junction protein, gamma 3, 30.2kDa; K07628 gap junction protein, epsilon 1 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction gamma-3 protein GN=GJC3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: gap junction gamma-3 protein-like [Tupaia chinensis] 
ENSG00000176406(RIMS2)	--	1.512287161	160	1.537626974	165	1.823752544	174	0.776502202	66	0.745194971	80	0.951398705	92	6.89E-05	-1.288456078	down	0.002962223	-1.051669671	down	0.016406886	-0.916532853	normal	0.000368489	-1.088138072	down	--	--	--	K15297|0|cjc:100395285|regulating synaptic membrane exocytosis protein 2-like; K15297 regulating synaptic membrane exocytosis protein 2 (A)	Insulin secretion (ko04911)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	C2 domain;; PDZ domain (Also known as DHR or GLGF)	Regulating synaptic membrane exocytosis protein 2 GN=RIMS2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: regulating synaptic membrane exocytosis protein 2 isoform X5 [Equus przewalskii]
ENSG00000176407(KCMF1)	--	64.09436368	1668	74.13422472	1809	56.93555418	1592	41.4063812	1156	47.25528715	1206	43.85914941	1101	0.131041576	-0.559187571	normal	0.060529805	-0.605764289	normal	0.186424675	-0.53969723	normal	7.72E-05	-0.57114819	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	"Drought induced 19 protein (Di19), zinc-binding;; Zinc finger, ZZ type"	E3 ubiquitin-protein ligase KCMF1 GN=KCMF1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: E3 ubiquitin-protein ligase KCMF1 isoform X1 [Ornithorhynchus anatinus]
ENSG00000176410(DNAJC30)	--	8.754145	352	7.3429	299	8.378644	331	6.027606	241	8.35137	337	7.449998	302	0.265960073	-0.57432494	normal	0.955903126	0.150459434	normal	0.958664066	-0.13990466	normal	0.55936442	-0.178593663	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	DnaJ homolog subfamily C member 30 GN=DNAJC30 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 30 [Galeopterus variegatus]
ENSG00000176422(SPRYD4)	--	1.93179	390	1.66833	340	2.02484	407	1.37007	276	1.31969	264	1.51855	306	0.385511187	-0.527155745	normal	0.803919552	-0.384476955	normal	0.717634212	-0.417991121	normal	0.050197244	-0.447183849	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPRY domain;; SPRY-associated domain	SPRY domain-containing protein 4 GN=SPRYD4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: SPRY domain-containing protein 4 [Equus caballus] 
ENSG00000176428(VPS37D)	--	4.231698485	118	4.497844825	130	4.277943388	127	3.225853433	90	4.509195388	123	3.949061152	112	0.892647338	-0.415407616	normal	0.964656955	-0.100082725	normal	0.958735862	-0.187245255	normal	0.630372726	-0.226891247	normal	--	--	--	K12185|4.42878e-124|ptr:472409|VPS37D; vacuolar protein sorting 37 homolog D (S. cerevisiae); K12185 ESCRT-I complex subunit VPS37 (A)	Endocytosis (ko04144)	--	--	Modifier of rudimentary (Mod(r)) protein	Vacuolar protein sorting-associated protein 37D OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 37D [Condylura cristata]
ENSG00000176438(SYNE3)	--	0.235088832	30	0.090883482	10	0.161243367	14	0.173799298	19	0.110621534	11	0.053525586	6	0.960797301	-0.647760848	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Nuclear envelope localisation domain;; Spectrin repeat	Nesprin-3 GN=SYNE3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nesprin-3 [Galeopterus variegatus]
ENSG00000176444(CLK2)	--	10.53246	494	9.263701734	445	9.392058	477	9.435900358	438	11.61832947	553	12.204782	600	0.945992542	-0.203738937	normal	0.899863702	0.291158494	normal	0.868929299	0.321770319	normal	0.579236144	0.147943179	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08823|0|ggo:101132105|CLK2; dual specificity protein kinase CLK2; K08823 CDC-like kinase [EC:2.7.12.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Dual specificity protein kinase CLK2 GN=CLK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: dual specificity protein kinase CLK2 isoform X3 [Equus caballus] 
ENSG00000176454(LPCAT4)	--	33.65811	1208	25.596543	911	32.581931	1170	27.901687	1004	27.281561	959	26.841113	944	0.907485713	-0.297277986	normal	0.977222489	0.052568148	normal	0.885220638	-0.317483433	normal	0.318400357	-0.199262166	normal	[I]	Lipid transport and metabolism	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K13512|0|hsa:254531|LPCAT4, AGPAT7, AYTL3, LPAAT-eta, LPEAT2; lysophosphatidylcholine acyltransferase 4 (EC:2.3.1.23 2.3.1.67 2.3.1.n6 2.3.1.n7 2.3.1.121); K13512 lysophospholipid acyltransferase [EC:2.3.1.23 2.3.1.-] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565)	--	--	Acyltransferase	Lysophospholipid acyltransferase LPCAT4 GN=LPCAT4 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: lysophospholipid acyltransferase LPCAT4 [Elephantulus edwardii]
ENSG00000176463(SLCO3A1)	--	18.610414	1323	17.142727	1206	18.265695	1327	15.95428	1136	20.05818	1260	15.545503	1099	0.943185675	-0.250368326	normal	0.980917933	0.041716091	normal	0.924994792	-0.279917344	normal	0.416676536	-0.1629272	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Molecular Function: protein binding (GO:0005515);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14353|0|mcf:102137273|SLCO3A1; solute carrier organic anion transporter family, member 3A1; K14353 solute carrier organic anion transporter family, member 3A (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Organic Anion Transporter Polypeptide (OATP) family;; Major Facilitator Superfamily;; Kazal-type serine protease inhibitor domain	Solute carrier organic anion transporter family member 3A1 GN=SLCO3A1 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: solute carrier organic anion transporter family member 3A1 isoform 1 [Ceratotherium simum simum]
ENSG00000176472(ZNF575)	--	3.176367	61	2.467916028	49	2.7633611	54	1.6727137	30	1.426664	27	2.155214	44	0.363179432	-1.017378982	normal	0.775612898	-0.845588203	normal	0.968628916	-0.294591789	normal	0.181831429	-0.719389408	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 575 GN=ZNF575 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	"Zinc finger protein 575, partial [Bos mutus]"
ENSG00000176473(WDR25)	--	4.48626391	160	3.9896048	131	3.820709	135	4.4364176	159	4.1614512	146	4.566962	157	0.967114362	-0.039496933	normal	0.96123792	0.133514523	normal	0.952058176	0.2073579	normal	0.85524416	0.095686923	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat"	WD repeat-containing protein 25 GN=WDR25 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: WD repeat-containing protein 25-like [Galeopterus variegatus] 
ENSG00000176476(SGF29)	--	5.958133696	131	5.776384921	127	6.139533619	137	5.42377989	120	6.838367395	150	7.69142175	170	0.961809707	-0.155458765	normal	0.949790943	0.21633493	normal	0.924071396	0.300088347	normal	0.787921283	0.135639654	normal	--	--	--	K11364|0|ptr:454015|CCDC101; coiled-coil domain containing 101; K11364 SAGA-associated factor 29 (A)	--	[R]	General function prediction only	SGF29 tudor-like domain	SAGA-associated factor 29 homolog GN=CCDC101 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: SAGA-associated factor 29 homolog isoform X1 [Panthera tigris altaica]
ENSG00000176485(PLA2G16)	--	32.67486606	1056	27.74126242	1038	31.79654083	1096	56.25923634	2303	50.61163769	2017	63.42961989	2472	9.67E-09	1.092969586	up	6.14E-06	0.93598261	normal	4.47E-10	1.164040779	up	1.45E-15	1.069328119	up	--	--	--	"K16817|7.43386e-102|pps:100977983|PLA2G16; phospholipase A2, group XVI; K16817 HRAS-like suppressor 3 [EC:3.1.1.32 3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; Ras signaling pathway (ko04014)	--	--	Lecithin retinol acyltransferase	HRAS-like suppressor 3 GN=PLA2G16 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: HRAS-like suppressor 3 isoform X1 [Oryctolagus cuniculus]
ENSG00000176531(PHLDB3)	--	5.759087111	234	5.133347367	212	6.1564222	263	4.21086963	187	3.558969348	141	4.558043651	169	0.8731094	-0.3517129	normal	0.381851632	-0.604469772	normal	0.19250153	-0.641690003	normal	0.053918243	-0.533845087	normal	--	--	--	--	--	--	--	PH domain	Pleckstrin homology-like domain family B member 3 GN=PHLDB3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology-like domain family B member 3 [Ceratotherium simum simum]
ENSG00000176532(PRR15)	--	2.545002	62	2.4547133	81	2.236015798	78	5.180259928	188	10.49553	318	16.509635	482	1.55E-07	1.546484016	up	7.33E-15	1.932011008	up	0	2.596103182	up	0.007452707	2.142083369	up	--	--	--	--	--	--	--	ATPase family AAA domain containing 4	Proline-rich protein 15 GN=PRR15 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: collagen alpha-1(I) chain isoform X2 [Mustela putorius furo] 
ENSG00000176533(GNG7)	--	0.141674	11	0.0126537	1	0.0372212	2	0.0257016	2	0.12475	9	0.050641	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04543|7.62667e-43|ptr:744391|GNG7; guanine nucleotide binding protein (G protein), gamma 7; K04543 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (Precursor) GN=GNG7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 isoform 1 [Canis lupus familiaris]
ENSG00000176542(USF3)	--	2.193468541	526	2.1459263	493	1.864290104	437	1.948979791	466	2.046430777	489	1.970186527	475	0.946149049	-0.204928629	normal	0.970379367	-0.033077858	normal	0.964949773	0.11163216	normal	0.893041215	-0.047355814	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	--	--	Helix-loop-helix DNA-binding domain	Basic helix-loop-helix domain-containing protein KIAA2018 GN=KIAA2018 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: basic helix-loop-helix domain-containing protein KIAA2018 homolog [Ceratotherium simum simum]
ENSG00000176563(CNTD1)	--	0.0939498	3	0	0	0.189869	5	0.0627039	2	0.030719302	0	0.124479	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cyclin, N-terminal domain"	Cyclin N-terminal domain-containing protein 1 GN=CNTD1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: cyclin N-terminal domain-containing protein 1 [Camelus ferus] 
ENSG00000176595(KBTBD11)	--	3.98783	416	3.935412	421	3.895222	415	4.016039	424	4.058333	423	2.3945658	250	0.970097817	-0.003339311	normal	0.969290388	-0.014537034	normal	0.01692562	-0.735981633	normal	0.553119185	-0.213210648	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10476|0|hsa:9920|KBTBD11, KLHDC7C; kelch repeat and BTB (POZ) domain containing 11; K10476 kelch repeat and BTB domain-containing protein 11 (A)"	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain"	Kelch repeat and BTB domain-containing protein 11 GN=KBTBD11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: kelch repeat and BTB domain-containing protein 11 [Odobenus rosmarus divergens]
ENSG00000176597(B3GNT5)	--	3.91085	216	4.172106	235	3.858853	200	8.309017	454	7.11573	399	6.943876	379	1.51E-05	1.035637853	up	0.020608975	0.738613756	normal	0.000666714	0.908831373	normal	1.15E-05	0.898280224	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K03766|0|hsa:84002|B3GNT5, B3GN-T5, beta3Gn-T5; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 (EC:2.4.1.206); K03766 beta-1,3-N-acetylglucosaminyltransferase 5 [EC:2.4.1.206] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase;; Fringe-like	"Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase GN=B3GNT5 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase [Galeopterus variegatus]"
ENSG00000176601(MAP3K19)	--	0.283715549	3	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17533|0|pps:100992106|MAP3K19, YSK4; mitogen-activated protein kinase kinase kinase 19; K17533 mitogen-activated protein kinase kinase kinase 19 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Mitogen-activated protein kinase kinase kinase 19 GN=MAP3K19 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 19 isoform 1 [Equus caballus]
ENSG00000176619(LMNB2)	--	43.0197	4173	41.6315	4163	45.3032	4557	58.5439	5696	54.7332	5285	41.1737	4007	0.797430214	0.417899808	normal	0.944627761	0.322749083	normal	0.98390413	-0.19378467	normal	0.43411182	0.195207663	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07611|0|hsa:84823|LMNB2, LAMB2, LMN2; lamin B2; K07611 lamin B (A)"	--	[DY]	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	Intermediate filament protein;; Lamin Tail Domain	Lamin-B2 (Precursor) GN=LMNB2 OS=Homo sapiens (Human) PE=1 SV=3	DY	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	PREDICTED: lamin-B2 [Camelus dromedarius]
ENSG00000176623(RMDN1)	--	20.95192857	549	14.2224287	467	20.71689275	561	16.87821039	512	15.0007694	458	14.84739947	455	0.963779139	-0.131114517	normal	0.969167895	-0.049340165	normal	0.882565006	-0.309497481	normal	0.513298746	-0.167585552	normal	--	--	--	--	--	--	--	Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Regulator of microtubule dynamics protein 1 GN=RMDN1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: regulator of microtubule dynamics protein 1 [Trichechus manatus latirostris]
ENSG00000176624(MEX3C)	--	24.32861419	909	24.06880926	960	21.42121727	768	25.43509988	936	27.81578106	1024	27.94492742	1053	0.978559693	0.011377022	normal	0.977020647	0.071573669	normal	0.558645179	0.446282287	normal	0.409208517	0.171137935	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: metal ion binding (GO:0046872);; 	"K15686|0|hsa:51320|MEX3C, MEX-3C, RKHD2, RNF194; mex-3 RNA binding family member C; K15686 RNA-binding protein MEX3 (A)"	--	[R]	General function prediction only	"KH domain;; KH domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RNA-binding E3 ubiquitin-protein ligase MEX3C GN=MEX3C OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RNA-binding E3 ubiquitin-protein ligase MEX3C [Mustela putorius furo]
ENSG00000176641(RNF152)	--	0.224029213	6	0.022260425	3	0.022382703	2	0.029765536	4	0.029130154	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K15705|5.12545e-146|ptr:468559|RNF152; ring finger protein 152; K15705 E3 ubiquitin-protein ligase RNF152 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF152 GN=RNF152 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF152 [Ceratotherium simum simum] 
ENSG00000176658(MYO1D)	--	5.606521241	499	4.614391689	429	4.933060958	473	2.489515269	237	3.346537261	325	3.016395006	267	1.36E-06	-1.099950951	down	0.710320579	-0.420256433	normal	0.00171591	-0.829712215	normal	6.49E-05	-0.77766844	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10356|0|hsa:4642|MYO1D, PPP1R108, myr4; myosin ID; K10356 myosin I (A)"	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; IQ calmodulin-binding motif	Unconventional myosin-Id GN=MYO1D OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-Id [Canis lupus familiaris]
ENSG00000176678(FOXL1)	--	0.370738143	26	0.32469463	12	1.16659952	51	1.171162697	84	2.127153254	77	0.666708886	35	0.000357314	1.605500722	up	5.61E-08	2.518625578	up	0.937709709	-0.532273319	normal	0.184735642	1.117662739	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09405|8.1369e-121|hsa:2300|FOXL1, FKH6, FKHL11, FREAC7; forkhead box L1; K09405 forkhead box protein L (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein L1 GN=FOXL1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: forkhead box protein L1 [Ailuropoda melanoleuca] 
ENSG00000176679(TGIF2LY)	--	0	0	0	0	0.0649984	0	0	0	0.1282847	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein TGIF2LY GN=TGIF2LY OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox protein TGIF2LX [Felis catus]
ENSG00000176681(LRRC37A)	--	0.739083213	58	0.632809061	59	0.656336582	60	0.500389033	40	0.676143825	51	0.955182959	79	0.919209759	-0.549259217	normal	0.969627654	-0.225423377	normal	0.941033912	0.380222698	normal	0.928757012	-0.077330399	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	LRRC37A/B like protein 1 C-terminal domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 37A (Precursor) GN=LRRC37A OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 37A-like [Pteropus alecto]
ENSG00000176692(FOXC2)	--	0.154263	6	0.0257015	1	0.147113	5	0.458705	18	0.270319	10	0.300119	12	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09396|0|hsa:2303|FOXC2, FKHL14, LD, MFH-1, MFH1; forkhead box C2; K09396 forkhead box protein C (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein C2 GN=FOXC2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	forkhead box protein C2 [Equus caballus] 
ENSG00000176697(BDNF)	--	3.268739622	245	3.647080085	272	4.200241027	307	7.653368214	570	10.53040489	782	7.039344106	524	6.81E-08	1.182349703	up	1.98E-13	1.497003599	up	0.006120662	0.760137355	normal	0.000145707	1.166016688	up	--	--	Molecular Function: receptor binding (GO:0005102);; 	K04355|0|mcc:701245|BDNF; brain-derived neurotrophic factor; K04355 brain-derived neurotrophic factor (A)	MAPK signaling pathway (ko04010);; cAMP signaling pathway (ko04024);; Neurotrophin signaling pathway (ko04722);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Alcoholism (ko05034)	--	--	Nerve growth factor family	Brain-derived neurotrophic factor (Precursor) GN=BDNF OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: brain-derived neurotrophic factor [Panthera tigris altaica]
ENSG00000176714(CCDC121)	--	2.517369	115	3.551582	154	3.086494	123	0.938218	41	0.963165	39	1.940021	81	6.32E-05	-1.484081363	down	7.20E-10	-1.961519572	down	0.661124256	-0.601772341	normal	0.000134787	-1.30312577	down	--	--	--	--	--	--	--	Domain of unknown function (DUF4515)	Coiled-coil domain-containing protein 121 GN=CCDC121 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 121 [Ceratotherium simum simum]
ENSG00000176715(ACSF3)	--	10.03594173	434	8.154769088	419	11.99396947	432	9.477364534	402	11.48457377	447	11.58178159	531	0.959974021	-0.140813648	normal	0.96726813	0.071647644	normal	0.901750517	0.288476722	normal	0.799902955	0.082581204	normal	[IQ]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K18660|0|hsa:197322|ACSF3; acyl-CoA synthetase family member 3; K18660 malonyl-CoA/methylmalonyl-CoA synthetase [EC:6.2.1.-] (A)	"Valine, leucine and isoleucine degradation (ko00280)"	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	"Acyl-CoA synthetase family member 3, mitochondrial (Precursor) GN=ACSF3 OS=Homo sapiens (Human) PE=1 SV=3"	I	Lipid transport and metabolism	"PREDICTED: acyl-CoA synthetase family member 3, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000176720(BOK)	--	13.43845	692	10.915516	574	13.915961	745	8.209391	425	7.827115	398	4.263035	220	0.006158848	-0.732045217	normal	0.249813832	-0.547964707	normal	0	-1.761034014	down	0.000311332	-0.969717087	normal	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	K02561|3.11347e-150|pps:100986084|BOK; BCL2-related ovarian killer; K02561 BCL2-related ovarian killer protein (A)	--	[T]	Signal transduction mechanisms	"Apoptosis regulator proteins, Bcl-2 family"	Bcl-2-related ovarian killer protein GN=BOK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bcl-2-related ovarian killer protein [Oryctolagus cuniculus]
ENSG00000176723(ZNF843)	--	0.210641873	8	0.080748829	5	0.2942678	17	0.541619292	20	0.220438637	13	0.315881068	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type"	Zinc finger protein 843 GN=ZNF843 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 843 [Equus caballus]
ENSG00000176731(C8orf59)	--	49.101802	392	47.022295	338	52.209994	375	59.641375	442	61.649844	438	46.618572	352	0.95977307	0.141836717	normal	0.838959292	0.351097732	normal	0.964473841	-0.099193642	normal	0.650536767	0.135230596	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C8orf59 GN=C8orf59 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: uncharacterized protein C8orf59 homolog [Galeopterus variegatus]
ENSG00000176732(PFN4)	--	0.201467588	3	0.452185567	7	0.236	3	0.511071	8	0.652147	9	0.744898	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05759|1.59031e-81|hsa:375189|PFN4; profilin family, member 4; K05759 profilin (A)"	Rap1 signaling pathway (ko04015);; Regulation of actin cytoskeleton (ko04810);; Shigellosis (ko05131);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	Profilin	Profilin-4 GN=PFN4 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: profilin-4 [Capra hircus]
ENSG00000176746(MAGEB6)	--	0.221299	7	0.370782	12	0.246569	7	0.564302	18	0.923657	29	0.787175	25	--	--	--	0.806833973	1.155422078	normal	0.526385606	1.631723969	normal	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen B6 GN=MAGEB6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: melanoma-associated antigen B1-like [Equus przewalskii]
ENSG00000176749(CDK5R1)	--	2.538412402	199	2.393153721	189	1.918610683	156	1.930415983	152	1.879326415	148	1.442396346	115	0.822462508	-0.415843114	normal	0.873101639	-0.370853147	normal	0.830952219	-0.443180092	normal	0.22054865	-0.412808588	normal	--	--	Cellular Component: cyclin-dependent protein kinase 5 holoenzyme complex (GO:0016533);; Molecular Function: cyclin-dependent protein kinase 5 activator activity (GO:0016534);; 	"K11716|0|bacu:103012840|CDK5R1; cyclin-dependent kinase 5, regulatory subunit 1 (p35); K11716 cyclin-dependent kinase 5 activator 1 (A)"	Alzheimer's disease (ko05010);; Cocaine addiction (ko05030)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Cyclin-dependent kinase 5 activator protein	"Cyclin-dependent kinase 5 activator 1, p25 (Precursor) GN=CDK5R1 OS=Homo sapiens (Human) PE=1 SV=1"	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 5 activator 1 [Balaenoptera acutorostrata scammoni]
ENSG00000176769(TCERG1L)	--	0.0411401	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	FF domain	Transcription elongation regulator 1-like protein GN=TCERG1L OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: transcription elongation regulator 1-like protein-like [Tupaia chinensis]
ENSG00000176771(NCKAP5)	--	2.324455484	219	2.159981899	149	2.640103698	195	3.030337414	243	3.24861418	351	2.82439848	311	0.961082799	0.118404381	normal	1.18E-06	1.206519307	up	0.112015828	0.661053912	normal	0.020545452	0.664592117	normal	--	--	--	--	--	--	--	"Nck-associated protein 5, Peripheral clock protein"	Nck-associated protein 5 GN=NCKAP5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nck-associated protein 5 [Ceratotherium simum simum]
ENSG00000176783(RUFY1)	--	12.60146021	731	13.5765911	809	14.92874429	820	13.52042491	749	13.51301062	791	12.38078017	708	0.976027639	0.004253218	normal	0.975252889	-0.05378688	normal	0.946886449	-0.219729458	normal	0.724807845	-0.091362132	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K12482|0|cjc:100390572|RUFY1; RUN and FYVE domain containing 1; K12482 RUN and FYVE domain-containing protein 1 (A)	Endocytosis (ko04144)	[R]	General function prediction only	RUN domain;; FYVE zinc finger	RUN and FYVE domain-containing protein 1 GN=RUFY1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: RUN and FYVE domain-containing protein 1 [Chrysochloris asiatica]
ENSG00000176788(BASP1)	--	223.9122576	7835	219.96012	7832	220.0191162	7963	184.3395535	6539	210.58399	7399	262.3511944	9288	0.971230623	-0.29163281	normal	0.993956085	-0.103456467	normal	0.988898107	0.213726855	normal	0.893577081	-0.044982495	normal	--	--	--	"K17272|3.32348e-17|hsa:10409|BASP1, CAP-23, CAP23, NAP-22, NAP22; brain abundant, membrane attached signal protein 1; K17272 brain acid soluble protein 1 (A)"	--	--	--	Brain acid soluble protein 1 (BASP1 protein)	Brain acid soluble protein 1 GN=BASP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	hypothetical protein CB1_001692002 [Camelus ferus]
ENSG00000176809(LRRC37A3)	--	1.980492166	208	1.8159256	174	1.999825278	210	1.809199243	182	1.871239636	173	3.104631507	311	0.943843633	-0.221724768	normal	0.965740722	-0.029484827	normal	0.371917916	0.554929697	normal	0.82445739	0.150558752	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	LRRC37A/B like protein 1 C-terminal domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 37A3 (Precursor) GN=LRRC37A3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 37A-like [Pteropus alecto]
ENSG00000176834(VSIG10)	--	6.655232246	601	6.371970715	634	7.655145933	632	7.2274095	688	6.425428	571	6.993983251	670	0.960301329	0.163819686	normal	0.957171409	-0.171986128	normal	0.972141631	0.075768987	normal	0.943643227	0.025808074	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain	V-set and immunoglobulin domain-containing protein 10 (Precursor) GN=VSIG10 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: V-set and immunoglobulin domain-containing protein 10 isoform X1 [Equus caballus]
ENSG00000176842(IRX5)	--	1.377942654	54	1.351867057	54	1.477316862	53	0.999405859	40	1.095359382	43	0.864913207	35	0.950593439	-0.448892367	normal	0.962902642	-0.339374234	normal	0.918146996	-0.586204118	normal	0.434955362	-0.4698106	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Iroquois-class homeodomain protein IRX-5 GN=IRX5 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: iroquois-class homeodomain protein IRX-5 isoform X2 [Bubalus bubalis]
ENSG00000176845(METRNL)	--	9.023630732	185	5.803773562	109	8.229993231	170	11.80832085	240	8.577498078	178	10.52223299	213	0.881146635	0.342176079	normal	0.2824727	0.678686099	normal	0.906581733	0.314522689	normal	0.204274106	0.422192857	normal	--	--	--	--	--	--	--	--	Meteorin-like protein (Precursor) GN=METRNL OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: meteorin-like protein [Chrysochloris asiatica]
ENSG00000176853(FAM91A1)	--	23.44722	1865	26.35889354	2078	27.02647	2090	28.233085	2280	25.85103	2034	27.70424	2209	0.953034408	0.258832824	normal	0.986085056	-0.052264087	normal	0.986210613	0.071548672	normal	0.687950593	0.091410739	normal	--	--	--	--	--	[S]	Function unknown	FAM91 C-terminus;; FAM91 N-terminus	Protein FAM91A1 GN=FAM91A1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM91A1 isoform X1 [Oryctolagus cuniculus] 
ENSG00000176871(WSB2)	--	35.2992274	1481	36.30892466	1527	32.54734185	1379	50.8160115	2098	39.5428729	1646	48.13455076	2009	0.473329784	0.471198245	normal	0.981876533	0.08675495	normal	0.207479987	0.534075642	normal	0.017423041	0.369488036	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K10342|0|hsa:55884|WSB2, SBA2; WD repeat and SOCS box containing 2; K10342 WD repeat and SOCS box-containing protein 2 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat;; SOCS box;; Nucleoporin Nup120/160"	WD repeat and SOCS box-containing protein 2 GN=WSB2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: WD repeat and SOCS box-containing protein 2 [Capra hircus]
ENSG00000176884(GRIN1)	--	0.06480587	5	0.077565195	6	0.120415002	8	0.207515018	17	0.13426082	10	0.087897589	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05208|0|ngi:103732604|Grin1; glutamate receptor, ionotropic, N-methyl D-aspartate 1; K05208 glutamate receptor ionotropic, NMDA 1 (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033);; Alcoholism (ko05034)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Receptor family ligand binding region;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site;; Calmodulin-binding domain C0 of NMDA receptor NR1 subunit"	"Glutamate receptor ionotropic, NMDA 1 (Precursor) GN=GRIN1 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, NMDA 1 isoform 1 [Odobenus rosmarus divergens] "
ENSG00000176890(TYMS)	--	68.1538	1930	82.929	2380	86.04069	2433	69.60411	1987	58.50228	1632	62.673116	1777	0.986649009	0.011150014	normal	0.138304338	-0.565310521	normal	0.532912322	-0.461247182	normal	0.047625845	-0.342931463	normal	[F]	Nucleotide transport and metabolism	--	"K00560|0|hsa:7298|TYMS, HST422, TMS, TS; thymidylate synthetase (EC:2.1.1.45); K00560 thymidylate synthase [EC:2.1.1.45] (A)"	Pyrimidine metabolism (ko00240);; One carbon pool by folate (ko00670)	[F]	Nucleotide transport and metabolism	Thymidylate synthase	Thymidylate synthase GN=TYMS OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: thymidylate synthase isoform 1 [Orcinus orca] 
ENSG00000176894(PXMP2)	--	45.21113619	1680	38.20228116	1485	39.99837295	1614	48.13279545	1859	49.96157811	1876	45.4755955	1510	0.981525012	0.115133153	normal	0.907719087	0.315483931	normal	0.980919445	-0.10428243	normal	0.60106109	0.112554985	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K13347|3.6674e-138|ggo:101123945|PXMP2; peroxisomal membrane protein 2; K13347 peroxisomal membrane protein 2 (A)	Peroxisome (ko04146)	[R]	General function prediction only	Mpv17 / PMP22 family;; Mpv17 / PMP22 family	Peroxisomal membrane protein 2 GN=PXMP2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisomal membrane protein 2 [Sorex araneus]
ENSG00000176896(TCEANC)	--	0.80556553	34	0.955922927	21	0.62211134	21	0.332065974	13	0.346297	17	0.432121889	22	0.520318441	-1.318159945	normal	0.985995042	-0.302061262	normal	0.988046157	0.054955945	normal	0.471525268	-0.567452482	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	--	--	[K]	Transcription	"Transcription factor S-II (TFIIS), central domain;; TFIIS helical bundle-like domain"	Transcription elongation factor A N-terminal and central domain-containing protein GN=TCEANC OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: transcription elongation factor A N-terminal and central domain-containing protein [Galeopterus variegatus]
ENSG00000176903(PNMA1)	--	30.5923	1363	29.2904	1330	29.8151	1351	36.8146	1656	36.5529	1627	41.3571	1846	0.948722122	0.249829042	normal	0.938841029	0.269084421	normal	0.595452712	0.441658845	normal	0.04652691	0.322024557	normal	--	--	--	--	--	--	--	PNMA	Paraneoplastic antigen Ma1 GN=PNMA1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: paraneoplastic antigen Ma1 [Canis lupus familiaris]
ENSG00000176907(C8orf4)	--	131.703	3850	130.962	3843	134.947	3901	92.8544	2756	120.172	3498	122.363	3579	0.334303499	-0.512871643	normal	0.98593093	-0.157064431	normal	0.988160669	-0.132525241	normal	0.13203832	-0.258016618	normal	--	--	--	--	--	--	--	Thyroid cancer protein 1	Uncharacterized protein C8orf4 GN=C8orf4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C8orf4 homolog [Chrysochloris asiatica]
ENSG00000176909(MAMSTR)	--	0.64112373	33	0.75680124	30	0.74445917	40	0.525031214	31	0.372450999	21	0.503983138	19	0.983742795	-0.115481365	normal	0.97092908	-0.505394633	normal	0.724490602	-1.024884798	normal	0.424006056	-0.559110829	normal	--	--	--	--	--	--	--	SAP domain	MEF2-activating motif and SAP domain-containing transcriptional regulator GN=MAMSTR OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: MEF2-activating motif and SAP domain-containing transcriptional regulator isoform 2 [Trichechus manatus latirostris]
ENSG00000176915(ANKLE2)	--	24.57590122	2222	24.319592	2194	25.78725168	2335	34.67785036	3198	38.84543532	3550	34.81794366	3133	0.403064194	0.494192633	normal	0.013573779	0.672461251	normal	0.741142588	0.415597602	normal	0.000242062	0.528472683	normal	--	--	--	--	--	--	--	Ankyrin repeats (many copies);; LEM domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat	Ankyrin repeat and LEM domain-containing protein 2 GN=ANKLE2 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: ankyrin repeat and LEM domain-containing protein 2 isoform X1 [Galeopterus variegatus] 
ENSG00000176919(C8G)	--	0	0	0	0	0.214112888	0	0.312257294	3	0	0	0.218874	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K03999|1.13942e-130|hsa:733|C8G, C8C; complement component 8, gamma polypeptide; K03999 complement component 8 subunit gamma (A)"	Complement and coagulation cascades (ko04610);; Prion diseases (ko05020);; Amoebiasis (ko05146);; Systemic lupus erythematosus (ko05322)	--	--	Lipocalin / cytosolic fatty-acid binding protein family	Complement component C8 gamma chain (Precursor) GN=C8G OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: complement component C8 gamma chain [Camelus ferus]
ENSG00000176920(FUT2)	--	0.79870222	42	0.89557543	51	1.2277813	52	0.52341874	29	0.49958882	28	0.47199094	17	0.952075393	-0.541203676	normal	0.748836372	-0.851908375	normal	0.026527131	-1.53922262	normal	0.065444007	-0.992861974	normal	--	--	Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: galactoside 2-alpha-L-fucosyltransferase activity (GO:0008107);; Cellular Component: membrane (GO:0016020);; 	"K00718|0|hsa:2524|FUT2, B12QTL1, SE, SEC2, Se2, sej; fucosyltransferase 2 (secretor status included) (EC:2.4.1.69); K00718 galactoside 2-L-fucosyltransferase 1/2 [EC:2.4.1.69] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601);; Glycosphingolipid biosynthesis - globo series (ko00603)	--	--	Glycosyl transferase family 11	Galactoside 2-alpha-L-fucosyltransferase 2 GN=FUT2 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: galactoside 2-alpha-L-fucosyltransferase 2-like [Equus caballus]
ENSG00000176927(EFCAB5)	--	0.087825	5	0.1785482	13	0.112742	5	0.225628326	11	0.11485585	6	0.137158	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	EF-hand calcium-binding domain-containing protein 5 GN=EFCAB5 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: EF-hand calcium-binding domain-containing protein 5 [Tupaia chinensis]
ENSG00000176928(GCNT4)	--	1.75E-32	0	2.37E-25	0	2.38E-25	0	3.41E-12	0	0.0711541	5	4.99E-22	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; 	"K09663|0|hsa:51301|GCNT4, C2GNT3; glucosaminyl (N-acetyl) transferase 4, core 2 (EC:2.4.1.102); K09663 beta-1,6-N-acetylglucosaminyltransferase 4 [EC:2.4.1.-] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	Core-2/I-Branching enzyme	"Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 GN=GCNT4 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4 [Galeopterus variegatus]"
ENSG00000176945(MUC20)	--	1.27091425	55	0.921946008	47	0.998596382	39	0.544661632	21	0.831469941	36	1.445963944	54	0.068319856	-1.356282518	normal	0.962802382	-0.391647673	normal	0.951125253	0.446423842	normal	0.589171473	-0.3640387	normal	--	--	--	--	--	--	--	--	Mucin-20 (Precursor) GN=MUC20 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: mucin-20 [Galeopterus variegatus]
ENSG00000176946(THAP4)	--	23.57303911	1108	21.9373072	1044	24.76367279	1145	18.509053	830	20.25048308	899	15.69779603	718	0.553348937	-0.446888072	normal	0.944458234	-0.236785221	normal	0.01129543	-0.680437846	normal	0.004552243	-0.451543093	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[S]	Function unknown	Domain of unknown function (DUF1794);; THAP domain	THAP domain-containing protein 4 GN=THAP4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: THAP domain-containing protein 4 isoform 1 [Odobenus rosmarus divergens]
ENSG00000176953(NFATC2IP)	--	16.9001	1221	16.13737	1214	18.01385	1295	18.254138	1498	18.4661	1390	17.37154	1379	0.938536691	0.263842011	normal	0.969163748	0.173687584	normal	0.980541743	0.082285785	normal	0.375580777	0.17270201	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-2 like Rad60 SUMO-like	NFATC2-interacting protein GN=NFATC2IP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: NFATC2-interacting protein [Tupaia chinensis]
ENSG00000176971(FIBIN)	--	0.0585919	2	0	0	0	0	0	0	0.0285265	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Fin bud initiation factor homolog (Precursor) GN=FIBIN OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: fin bud initiation factor homolog [Mustela putorius furo] 
ENSG00000176974(SHMT1)	--	42.87865	1534	33.33391401	1437	33.83714	1409	35.44147867	1301	32.01481624	1282	37.88313911	1504	0.937178837	-0.268217663	normal	0.967448365	-0.185883109	normal	0.981344157	0.085752416	normal	0.575135028	-0.120741799	normal	[E]	Amino acid transport and metabolism	Biological Process: biosynthetic process (GO:0009058);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	K00600|0|pps:100969107|SHMT1; serine hydroxymethyltransferase 1 (soluble); K00600 glycine hydroxymethyltransferase [EC:2.1.2.1] (A)	"Glycine, serine and threonine metabolism (ko00260);; Cyanoamino acid metabolism (ko00460);; Glyoxylate and dicarboxylate metabolism (ko00630);; One carbon pool by folate (ko00670);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Serine hydroxymethyltransferase;; Aminotransferase class I and II	"Serine hydroxymethyltransferase, cytosolic GN=SHMT1 OS=Homo sapiens (Human) PE=1 SV=1"	E	Amino acid transport and metabolism	"PREDICTED: serine hydroxymethyltransferase, cytosolic [Pteropus alecto]"
ENSG00000176978(DPP7)	--	56.85483208	1515	63.98626095	1760	54.92166696	1500	53.57963157	1444	55.03320491	1482	65.09079904	1756	0.980543397	-0.099975444	normal	0.941525151	-0.269204101	normal	0.96250216	0.218834795	normal	0.850207812	-0.049174162	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; 	"K01276|0|hsa:29952|DPP7, DPP2, DPPII, QPP; dipeptidyl-peptidase 7 (EC:3.4.14.2); K01276 dipeptidyl-peptidase II [EC:3.4.14.2] (A)"	--	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Serine carboxypeptidase S28;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Dipeptidyl peptidase 2 (Precursor) GN=DPP7 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dipeptidyl peptidase 2 [Galeopterus variegatus]
ENSG00000176986(SEC24C)	--	33.36792	2846	33.833057	2863	34.51553	2952	37.32243086	3174	35.80908	3020	37.18474	3166	0.986534598	0.126469532	normal	0.989157539	0.055565743	normal	0.988539096	0.092631262	normal	0.691082661	0.090817794	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: COPII vesicle coat (GO:0030127);; 	K14007|0|hsa:9632|SEC24C; SEC24 family member C; K14007 protein transport protein SEC24 (A)	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec23/Sec24 trunk domain;; Sec23/Sec24 helical domain;; Sec23/Sec24 beta-sandwich domain;; Sec23/Sec24 zinc finger;; Gelsolin repeat	Protein transport protein Sec24C GN=SEC24C OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein transport protein Sec24C [Ailuropoda melanoleuca] 
ENSG00000176994(SMCR8)	--	10.3468	1772	13.2711	2282	10.0981	1728	10.6534	1810	11.2358	1908	15.2147	2604	0.98583197	-0.000220981	normal	0.943592056	-0.279461327	normal	0.086105171	0.582916384	normal	0.814970207	0.108374962	normal	--	--	--	--	--	--	--	Vesicle coat protein involved in Golgi to plasma membrane transport	Smith-Magenis syndrome chromosomal region candidate gene 8 protein GN=SMCR8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: smith-Magenis syndrome chromosomal region candidate gene 8 protein isoform X1 [Tupaia chinensis] 
ENSG00000177000(MTHFR)	--	7.2974988	668	7.492172	613	5.46333009	549	5.37695299	387	3.76673667	400	8.142413584	635	0.000904779	-0.81584853	normal	0.062051599	-0.635357559	normal	0.949589408	0.201143395	normal	0.27284134	-0.383874887	normal	[E]	Amino acid transport and metabolism	Molecular Function: methylenetetrahydrofolate reductase (NAD(P)H) activity (GO:0004489);; Biological Process: methionine metabolic process (GO:0006555);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00297|0|hsa:4524|MTHFR; methylenetetrahydrofolate reductase (NAD(P)H) (EC:1.5.1.20); K00297 methylenetetrahydrofolate reductase (NADPH) [EC:1.5.1.20] (A)	One carbon pool by folate (ko00670);; Carbon metabolism (ko01200)	[E]	Amino acid transport and metabolism	Methylenetetrahydrofolate reductase	Methylenetetrahydrofolate reductase GN=MTHFR OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: methylenetetrahydrofolate reductase isoform X1 [Galeopterus variegatus]
ENSG00000177025(C19orf18)	--	0	0	0	0	0.075404	0	0	0	0	0	0.150402	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C19orf18 (Precursor) GN=C19orf18 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C19orf18 homolog [Camelus ferus]
ENSG00000177030(DEAF1)	--	8.19945	400	8.58802	428	7.40291	373	9.33221	457	11.9177	584	11.0409	545	0.956489123	0.160783831	normal	0.669167603	0.425638873	normal	0.281250812	0.536977649	normal	0.066647883	0.380360734	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[DK]	"Cell cycle control, cell division, chromosome partitioning;; Transcription"	SAND domain;; MYND finger	Deformed epidermal autoregulatory factor 1 homolog GN=DEAF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: deformed epidermal autoregulatory factor 1 homolog [Chrysochloris asiatica]
ENSG00000177034(MTX3)	--	5.513935244	622	5.734990538	631	6.043585976	584	5.500459005	598	4.969454556	564	5.160197553	585	0.970378585	-0.087381198	normal	0.954398387	-0.182907429	normal	0.973460131	-0.005808159	normal	0.736237718	-0.093875595	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: protein targeting to mitochondrion (GO:0006626);; 	K17776|0|ptr:736479|MTX3; metaxin 3; K17776 metaxin (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Tom37 C-terminal domain;; Outer mitochondrial membrane transport complex protein;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain"	Metaxin-3 GN=MTX3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: metaxin-3 isoform X1 [Ailuropoda melanoleuca]
ENSG00000177042(TMEM80)	--	9.283636	200	13.0705906	242	10.7958	222	7.87052	168	7.006463	169	10.239823	230	0.925463645	-0.280020297	normal	0.525939215	-0.535383871	normal	0.966318899	0.04249831	normal	0.469077809	-0.24812777	normal	--	--	--	--	--	[S]	Function unknown	Predicted membrane protein	Transmembrane protein 80 GN=TMEM80 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane protein 80 [Physeter catodon]
ENSG00000177045(SIX5)	--	20.53766895	986	19.86136283	1024	19.73152396	1003	17.3049335	854	16.27515571	839	20.28836889	987	0.942534252	-0.237785264	normal	0.893632628	-0.308395446	normal	0.97919404	-0.031443266	normal	0.344499255	-0.189754301	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox domain;; Homeobox KN domain	Homeobox protein SIX5 GN=SIX5 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein SIX5 [Trichechus manatus latirostris]
ENSG00000177051(FBXO46)	--	14.713764	674	14.55365714	597	18.469424	756	12.903824	555	14.51626	616	18.62824	774	0.881579827	-0.310312065	normal	0.972925805	0.023713726	normal	0.976246291	0.025605268	normal	0.825235823	-0.07942283	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10320|0|pps:100984218|FBXO46; F-box protein 46; K10320 F-box protein 46 (A)	--	--	--	F-box-like;; F-box domain	F-box only protein 46 GN=FBXO46 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: F-box only protein 46 isoform X2 [Canis lupus familiaris] 
ENSG00000177054(ZDHHC13)	--	16.565794	608	18.84003207	688	18.602129	678	14.60517	542	13.387706	492	15.2294	563	0.950591103	-0.196085529	normal	0.375747478	-0.503860487	normal	0.913151247	-0.275765764	normal	0.097071099	-0.326822198	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K18932|0|pon:100174171|ZDHHC13; zinc finger, DHHC-type containing 13 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; DHHC palmitoyltransferase;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Palmitoyltransferase ZDHHC13 GN=ZDHHC13 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC13 [Camelus ferus] 
ENSG00000177058(SLC38A9)	--	13.27079015	436	15.49355762	426	10.60551538	366	19.30300076	494	15.23093879	438	15.36073863	491	0.959491832	0.148857629	normal	0.969446074	0.018585814	normal	0.707631778	0.414105578	normal	0.460792926	0.191084994	normal	--	--	--	"K14995|0|pps:100988415|SLC38A9; solute carrier family 38, member 9; K14995 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 9 (A)"	--	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Putative sodium-coupled neutral amino acid transporter 9 GN=SLC38A9 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: putative sodium-coupled neutral amino acid transporter 9 isoform X1 [Felis catus] 
ENSG00000177076(ACER2)	--	2.5969735	216	3.301019813	236	2.792210176	223	2.9979451	246	2.98326601	239	3.862150034	311	0.956122485	0.155756103	normal	0.965967515	-0.003182534	normal	0.636315183	0.468875053	normal	0.506224107	0.21732812	normal	--	--	"Biological Process: ceramide metabolic process (GO:0006672);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides (GO:0016811);; "	K01441|0|pps:100971165|ACER2; alkaline ceramidase 2; K01441 alkaline ceramidase [EC:3.5.1.23] (A)	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[I]	Lipid transport and metabolism	Ceramidase	Alkaline ceramidase 2 GN=ACER2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: alkaline ceramidase 2 isoform X2 [Oryctolagus cuniculus]
ENSG00000177082(WDR73)	--	9.404713922	1059	9.38299783	1069	8.405261	993	10.5546441	1204	11.71757204	1319	10.511188	1228	0.970618782	0.154090779	normal	0.924471522	0.281397215	normal	0.907584495	0.297745013	normal	0.174410704	0.244057835	normal	--	--	--	--	--	[B]	Chromatin structure and dynamics	"WD domain, G-beta repeat"	WD repeat-containing protein 73 GN=WDR73 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: WD repeat-containing protein 73 [Orcinus orca]
ENSG00000177084(POLE)	--	14.99883759	2507	14.72036319	2499	15.1074725	2514	14.22387513	2373	15.68545735	2583	15.49518821	2607	0.985521376	-0.110012845	normal	0.988485237	0.026254557	normal	0.988574325	0.044088446	normal	0.96950024	-0.012648145	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed DNA polymerase activity (GO:0003887);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	"K02324|0|hsa:5426|POLE, CRCS12, FILS, POLE1; polymerase (DNA directed), epsilon, catalytic subunit (EC:2.7.7.7); K02324 DNA polymerase epsilon subunit 1 [EC:2.7.7.7] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; DNA replication (ko03030);; Base excision repair (ko03410);; Nucleotide excision repair (ko03420);; HTLV-I infection (ko05166)	[L]	"Replication, recombination and repair"	"Domain of unknown function (DUF1744);; DNA polymerase family B, exonuclease domain;; DNA polymerase family B;; Predicted 3'-5' exonuclease related to the exonuclease domain of PolB;; RNase_H superfamily"	DNA polymerase epsilon catalytic subunit A GN=POLE OS=Homo sapiens (Human) PE=1 SV=5	L	"Replication, recombination and repair"	PREDICTED: DNA polymerase epsilon catalytic subunit A [Oryctolagus cuniculus]
ENSG00000177096(FAM109B)	--	0.049191801	2	0	0	0	0	0.024242572	1	0.024013818	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PH domain	Sesquipedalian-2 GN=FAM109B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sesquipedalian-2 [Equus przewalskii] 
ENSG00000177098(SCN4B)	--	0.045902458	4	0.06720832	6	0.037428335	2	0.012856591	1	0.025261137	1	0.012783231	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04848|5.25106e-123|pps:100981777|SCN4B; sodium channel, voltage-gated, type IV, beta subunit; K04848 voltage-gated sodium channel type IV beta (A)"	Adrenergic signaling in cardiomyocytes (ko04261)	--	--	Immunoglobulin V-set domain	Sodium channel subunit beta-4 (Precursor) GN=SCN4B OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel subunit beta-4 [Mustela putorius furo] 
ENSG00000177103(DSCAML1)	--	0.189821595	2	0.00712595	1	0	0	0.0190336	3	0.034214397	4	0.049547283	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K06768|0|hsa:57453|DSCAML1; Down syndrome cell adhesion molecule like 1; K06768 Down syndrome cell adhesion molecule-like protein 1 (A)	--	[T]	Signal transduction mechanisms	"Immunoglobulin I-set domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain;; Natural killer cell receptor 2B4;; Interferon-alpha/beta receptor, fibronectin type III"	Down syndrome cell adhesion molecule-like protein 1 (Precursor) GN=DSCAML1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: Down syndrome cell adhesion molecule-like protein 1 [Orycteropus afer afer]
ENSG00000177105(RHOG)	--	44.13418648	890	38.80139625	787	47.84441942	997	43.70980486	893	39.66547424	812	37.82805929	778	0.977952432	-0.025932732	normal	0.976193438	0.023644804	normal	0.803245805	-0.365485537	normal	0.579236144	-0.128195991	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07863|1.14337e-140|rno:308875|Rhog, Arhg; ras homolog family member G; K07863 Ras homolog gene family, member G (A)"	Bacterial invasion of epithelial cells (ko05100);; Salmonella infection (ko05132)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rho-related GTP-binding protein RhoG (Precursor) GN=RHOG OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rho-related GTP-binding protein RhoG isoform 1 [Odobenus rosmarus divergens]
ENSG00000177106(EPS8L2)	--	38.11465898	2129	37.87025954	2331	41.99636111	2352	55.33357117	3246	55.80002164	3343	57.01526595	3288	0.101633414	0.577315125	normal	0.417486353	0.498496396	normal	0.501436898	0.474771444	normal	0.000371184	0.514937857	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17277|0|hsa:64787|EPS8L2, EPS8R2; EPS8-like 2; K17277 epidermal growth factor receptor kinase substrate 8 (A)"	--	[T]	Signal transduction mechanisms	Phosphotyrosine-binding domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Epidermal growth factor receptor kinase substrate 8-like protein 2 GN=EPS8L2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 2 [Odobenus rosmarus divergens]
ENSG00000177108(ZDHHC22)	--	0.22123	14	0.184637095	12	0.0611724	3	0.126305	8	0.077430349	4	0.062794866	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K18932|0|ptr:467517|ZDHHC22; zinc finger, DHHC-type containing 22; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC22 GN=ZDHHC22 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC22 [Elephantulus edwardii]
ENSG00000177119(ANO6)	--	32.82840274	3412	34.1280372	3506	34.20442159	3410	43.14081559	4493	38.53969708	4002	37.58130206	3875	0.887121317	0.366085114	normal	0.985003286	0.169400184	normal	0.984124619	0.176059838	normal	0.173903194	0.238588817	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[S]	Function unknown	Calcium-activated chloride channel	Anoctamin-6 GN=ANO6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: anoctamin-6 [Tupaia chinensis]
ENSG00000177125(ZBTB34)	--	2.853573567	289	2.97633005	302	2.647508618	267	2.166528075	224	2.69586643	273	3.206685234	326	0.800264812	-0.396004238	normal	0.952788346	-0.166198356	normal	0.913655098	0.278311974	normal	0.834597542	-0.080325645	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10508|0|ptr:740152|ZBTB34; zinc finger and BTB domain containing 34; K10508 zinc finger and BTB domain-containing protein 34 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; BED zinc finger"	Zinc finger and BTB domain-containing protein 34 GN=ZBTB34 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 34 [Canis lupus familiaris]
ENSG00000177138(FAM9B)	--	0	0	0	0	0	0	0.079976321	3	0.078393381	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cor1/Xlr/Xmr conserved region	Protein FAM9B GN=FAM9B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000177144(NUDT4P1)	--	0.11264	2	0.221922	4	0.220257	3	0	0	0.109213	1	0.111755	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K07766|5.71194e-120|ptr:736394|NUDT4; nudix (nucleoside diphosphate linked moiety X)-type motif 4; K07766 diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] (A)	--	[T]	Signal transduction mechanisms	NUDIX domain	Diphosphoinositol polyphosphate phosphohydrolase 2 GN=NUDT4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: diphosphoinositol polyphosphate phosphohydrolase 2 isoform 1 [Tursiops truncatus] 
ENSG00000177150(FAM210A)	--	10.010113	434	13.867242	537	11.32956	453	11.1946013	475	8.640296	379	11.35717762	492	0.966151923	0.099064921	normal	0.345672466	-0.522390114	normal	0.965421484	0.110501763	normal	0.731424545	-0.102623519	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1279)	Protein FAM210A GN=FAM210A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM210A [Leptonychotes weddellii]
ENSG00000177156(TALDO1)	--	153.20179	3377	170.31042	3807	153.87168	3469	206.7709	4687	196.6392	4332	193.6762	4301	0.692895137	0.441919024	normal	0.986286763	0.16489068	normal	0.94956162	0.301742497	normal	0.069442706	0.30077852	normal	[G]	Carbohydrate transport and metabolism	Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K00616|0|hsa:6888|TALDO1, TAL, TAL-H, TALDOR, TALH; transaldolase 1 (EC:2.2.1.2); K00616 transaldolase [EC:2.2.1.2] (A)"	Pentose phosphate pathway (ko00030);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Transaldolase	Transaldolase GN=TALDO1 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: transaldolase [Leptonychotes weddellii]
ENSG00000177169(ULK1)	--	22.8936	2385	27.8583	2899	23.0408	2441	21.16	2178	23.0434	2398	28.1371	2956	0.979970668	-0.16170851	normal	0.942000133	-0.29498075	normal	0.956273407	0.267731587	normal	0.874050766	-0.056955031	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08269|0|hsa:8408|ULK1, ATG1, ATG1A, UNC51, Unc51.1, hATG1; unc-51 like autophagy activating kinase 1 (EC:2.7.11.1); K08269 serine/threonine-protein kinase ULK/ATG1 [EC:2.7.11.1] (A)"	Regulation of autophagy (ko04140);; mTOR signaling pathway (ko04150);; AMPK signaling pathway (ko04152)	[OUT]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport;; Signal transduction mechanisms"	Protein kinase domain;; Protein tyrosine kinase;; Domain of unknown function (DUF3543);; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family	Serine/threonine-protein kinase ULK1 GN=ULK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase ULK1 isoform X1 [Sus scrofa]
ENSG00000177181(RIMKLA)	--	1.081016586	148	1.446249915	209	1.138826835	126	0.913070458	114	0.277896715	48	0.637714266	92	0.875031199	-0.402617902	normal	1.34E-13	-2.109068291	down	0.855106885	-0.45558365	normal	0.055170931	-0.950159897	normal	[HJ]	"Coenzyme transport and metabolism;; Translation, ribosomal structure and biogenesis"	Molecular Function: glutathione synthase activity (GO:0004363);; Molecular Function: ATP binding (GO:0005524);; Biological Process: glutathione biosynthetic process (GO:0006750);; Molecular Function: metal ion binding (GO:0046872);; 	"K18311|0|ptr:748944|RIMKLA, FAM80A; ribosomal modification protein rimK-like family member A; K18311 N-acetylaspartylglutamate/N-acetylaspartylglutamylglutamate synthase [EC:6.3.2.41 6.3.2.42] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250)"	--	--	"RimK-like ATP-grasp domain;; Prokaryotic glutathione synthetase, ATP-grasp domain;; ATP-grasp domain;; ATP-grasp domain"	N-acetylaspartylglutamate synthase A GN=RIMKLA OS=Homo sapiens (Human) PE=2 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: N-acetylaspartyl-glutamate synthetase A isoform X1 [Tupaia chinensis] 
ENSG00000177182(CLVS1)	--	0.0210022	1	0.021184	1	0	0	0.020964	1	0.101981	4	0.0208463	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	"CRAL/TRIO domain;; CRAL/TRIO, N-terminal domain;; Divergent CRAL/TRIO domain"	Clavesin-1 GN=CLVS1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: clavesin-1 [Leptonychotes weddellii]
ENSG00000177189(RPS6KA3)	--	32.99543585	3806	36.83064087	4206	28.44565597	3487	36.9713811	4333	36.869336	4326	34.170276	3815	0.987240851	0.156199287	normal	0.992247427	0.019151468	normal	0.988618728	0.121354919	normal	0.674752071	0.09561646	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K04373|0|pps:100986115|RPS6KA3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; K04373 p90 ribosomal S6 kinase [EC:2.7.11.1] (A)"	MAPK signaling pathway (ko04010);; Oocyte meiosis (ko04114);; mTOR signaling pathway (ko04150);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Progesterone-mediated oocyte maturation (ko04914)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family;; Protein kinase C terminal domain;; PhoP regulatory network protein YrbL;; Phosphotransferase enzyme family	Ribosomal protein S6 kinase alpha-3 GN=RPS6KA3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ribosomal protein S6 kinase alpha-3 isoform X1 [Chrysochloris asiatica]
ENSG00000177191(B3GNT8)	--	0.13779	4	0.10171	3	0.0985639	2	0.171621	5	0.066641	1	0.135412	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K09665|0|hsa:374907|B3GNT8, B3GALT7, BGALT15, beta3Gn-T8; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8; K09665 beta-1,3-N-acetylglucosaminyltransferase 8 [EC:2.4.1.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8 [Orycteropus afer afer]"
ENSG00000177192(PUS1)	--	40.531514	1061	34.55651605	1027	34.59365884	979	37.50288611	957	34.838609	973	30.63323006	886	0.963827025	-0.179392392	normal	0.975170484	-0.099200929	normal	0.968111887	-0.1520466	normal	0.506902737	-0.144676027	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: pseudouridine synthesis (GO:0001522);; Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA modification (GO:0009451);; Molecular Function: pseudouridine synthase activity (GO:0009982);; 	K06173|0|pps:100992400|PUS1; pseudouridylate synthase 1; K06173 tRNA pseudouridine38-40 synthase [EC:5.4.99.12] (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	tRNA pseudouridine synthase	"tRNA pseudouridine synthase A, mitochondrial (Precursor) GN=PUS1 OS=Homo sapiens (Human) PE=1 SV=3"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: tRNA pseudouridine synthase A, mitochondrial [Galeopterus variegatus]"
ENSG00000177200(CHD9)	--	10.00943291	1707	12.31920689	2050	11.16884206	1852	13.0863962	2444	13.3119365	2660	11.1115705	2307	0.41377544	0.486581218	normal	0.877424858	0.354145858	normal	0.921010465	0.308416388	normal	0.01307887	0.380564065	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: hydrolase activity, acting on acid anhydrides (GO:0016817);; "	K14438|0|ptr:454088|CHD9; chromodomain helicase DNA binding protein 9; K14438 chromodomain-helicase-DNA-binding protein 9 [EC:3.6.4.12] (A)	--	[K]	Transcription	"SNF2 family N-terminal domain;; BRK domain;; Chromo (CHRromatin Organisation MOdifier) domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase"	Chromodomain-helicase-DNA-binding protein 9 GN=CHD9 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: chromodomain-helicase-DNA-binding protein 9 isoform X2 [Ailuropoda melanoleuca] 
ENSG00000177202(SPACA4)	--	0.908526	13	0.135633	2	0.331022	4	0	0	0	0	0.0683911	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	u-PAR/Ly-6 domain	Sperm acrosome membrane-associated protein 4 (Precursor) GN=SPACA4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sperm acrosome membrane-associated protein 4 [Balaenoptera acutorostrata scammoni]
ENSG00000177225(PDDC1)	--	24.71129982	1243	30.88096803	1288	24.10464632	1261	22.5485265	1123	23.29423719	1144	21.6946024	1047	0.96707671	-0.177070226	normal	0.963942925	-0.192232437	normal	0.92618541	-0.276234157	normal	0.243539241	-0.215767421	normal	--	--	--	--	--	--	--	DJ-1/PfpI family	Parkinson disease 7 domain-containing protein 1 (Precursor) GN=PDDC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: Parkinson disease 7 domain-containing protein 1 [Eptesicus fuscus]
ENSG00000177238(TRIM72)	--	0	0	0	0	0	0	0	0	0	0	0.040960107	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12036|0|ptr:467960|TRIM72; tripartite motif containing 72, E3 ubiquitin protein ligase; K12036 tripartite motif-containing protein 72 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	Tripartite motif-containing protein 72 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 72 [Galeopterus variegatus]
ENSG00000177239(MAN1B1)	--	29.23035012	1730	27.136742	1617	28.325126	1691	33.000338	1885	31.74437623	1803	33.89339455	2015	0.983345586	0.092881186	normal	0.978863359	0.135533079	normal	0.956447214	0.24441126	normal	0.421912358	0.157888571	normal	--	--	"Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: membrane (GO:0016020);; "	"K01230|0|hsa:11253|MAN1B1, ERMAN1, MANA-ER, MRT15; mannosidase, alpha, class 1B, member 1 (EC:3.2.1.113); K01230 mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 47	"Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase GN=MAN1B1 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase [Trichechus manatus latirostris]"
ENSG00000177272(KCNA3)	--	0.0241152	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04876|0|hsa:3738|KCNA3, HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3; potassium voltage-gated channel, shaker-related subfamily, member 3; K04876 potassium voltage-gated channel Shaker-related subfamily A member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel;; Polycystin cation channel	Potassium voltage-gated channel subfamily A member 3 GN=KCNA3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily A member 3 [Odobenus rosmarus divergens]
ENSG00000177283(FZD8)	--	5.33356	305	3.83414	228	3.69816	223	4.99796	291	7.06824	407	6.1175	355	0.96344331	-0.09811626	normal	0.004937214	0.810491765	normal	0.089814682	0.658911462	normal	0.109762229	0.457294042	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	K02375|0|rno:100909849|frizzled-8-like; K02375 frizzled 5/8 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-8 (Precursor) GN=FZD8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: frizzled family receptor 8 [Myotis lucifugus]
ENSG00000177291(GJD4)	--	0	0	0	0	0	0	0	0	0	0	0.0383087	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07630|0|hsa:219770|GJD4, CX40.1; gap junction protein, delta 4, 40.1kDa; K07630 Gap junction delta-4 protein (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction delta-4 protein GN=GJD4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: gap junction delta-4 protein [Equus przewalskii]
ENSG00000177300(CLDN22)	--	0.49142	20	0.147232	6	0.244757	9	0.557387	23	0.404923	16	0.510375	21	0.987769446	0.159378777	normal	--	--	--	0.932353947	1.091219486	normal	0.347766377	0.755606404	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06087|5.37147e-103|hsa:53842|CLDN22, CLDN21; claudin 22; K06087 claudin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-22 GN=CLDN22 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: claudin-22 [Galeopterus variegatus]
ENSG00000177301(KCNA2)	--	0.058987817	7	0.039998664	3	0.0405606	4	0	0	0.008260454	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04875|0|ptr:469413|KCNA2; potassium voltage-gated channel, shaker-related subfamily, member 2; K04875 potassium voltage-gated channel Shaker-related subfamily A member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily A member 2 GN=KCNA2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	potassium voltage-gated channel subfamily A member 2 [Bos taurus] 
ENSG00000177302(TOP3A)	--	13.18299805	1435	13.985579	1456	14.7466201	1452	13.619848	1586	13.39641	1494	14.804123	1602	0.979704969	0.113394259	normal	0.983403489	0.015727109	normal	0.977921728	0.133408922	normal	0.709106598	0.087252839	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase activity (GO:0003916);; Cellular Component: chromosome (GO:0005694);; Biological Process: DNA topological change (GO:0006265);; Molecular Function: zinc ion binding (GO:0008270);; 	"K03165|0|hsa:7156|TOP3A, TOP3, ZGRF7; topoisomerase (DNA) III alpha (EC:5.99.1.2); K03165 DNA topoisomerase III [EC:5.99.1.2] (A)"	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	DNA topoisomerase;; GRF zinc finger;; Toprim domain;; Topoisomerase DNA binding C4 zinc finger	DNA topoisomerase 3-alpha GN=TOP3A OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA topoisomerase 3-alpha isoform X1 [Condylura cristata]
ENSG00000177303(CASKIN2)	--	9.24121101	753	6.91054022	729	11.00807472	759	8.334371864	772	6.816743187	671	10.56275375	774	0.97637246	0.005108425	normal	0.965252676	-0.140728201	normal	0.976374602	0.019902968	normal	0.905931405	-0.036729007	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; SAM domain (Sterile alpha motif);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; Variant SH3 domain	Caskin-2 GN=CASKIN2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: caskin-2 isoform X1 [Felis catus] 
ENSG00000177311(ZBTB38)	--	19.4608954	2034	22.90905575	1981	22.84992279	2219	38.17549671	3810	41.7553205	4457	46.51346186	4684	2.23E-05	0.874149194	normal	9.61E-10	1.147817833	up	1.25E-08	1.069026957	up	1.18E-13	1.034479058	up	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10510|0|hsa:253461|ZBTB38, CIBZ, PPP1R171, ZNF921; zinc finger and BTB domain containing 38; K10510 zinc finger and BTB domain-containing protein 38 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; BTB/POZ domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 38 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 38 [Ursus maritimus]
ENSG00000177352(CCDC71)	--	9.00925	325	7.99659	292	8.74418	322	10.4652	379	9.29328	336	8.57813	314	0.948548681	0.190093104	normal	0.949905636	0.180195766	normal	0.967339609	-0.044376509	normal	0.743840289	0.110366276	normal	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 71L	Coiled-coil domain-containing protein 71 GN=CCDC71 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 71 [Ceratotherium simum simum]
ENSG00000177359(OVOS2)	--	2.690014721	25	1.668057846	16	3.162215909	26	0.135396325	3	1.774802369	14	1.100416592	10	0.02253483	-2.573059528	normal	--	--	--	0.797452564	-1.264420544	normal	--	--	--	--	--	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; Alpha-2-macroglobulin family N-terminal region;; Alpha-2-macroglobulin family;; A-macroglobulin receptor;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region;; Prenyltransferase-like	Ovostatin homolog 2 (Precursor) GN=OVOS2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ovostatin homolog 2 [Equus przewalskii]
ENSG00000177363(LRRN4CL)	--	0.162517	7	0.159168	7	0.0222563	0	0.0915039	4	0.0449181	1	0.0683726	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Fibronectin type III domain	LRRN4 C-terminal-like protein (Precursor) GN=LRRN4CL OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LRRN4 C-terminal-like protein [Tupaia chinensis]
ENSG00000177370(TIMM22)	--	11.8846	664	12.5561	710	12.7334	717	15.4194	865	15.6503	867	14.1962	795	0.829231539	0.349973399	normal	0.924106682	0.266272454	normal	0.966956419	0.140408944	normal	0.196372756	0.251879132	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K17790|3.47423e-92|rno:79463|Timm22; translocase of inner mitochondrial membrane 22 homolog (yeast); K17790 mitochondrial import inner membrane translocase subunit TIM22 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim17/Tim22/Tim23/Pmp24 family	Mitochondrial import inner membrane translocase subunit Tim22 GN=TIMM22 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim22 [Ceratotherium simum simum]
ENSG00000177374(HIC1)	--	0.569202	36	1.255520005	45	1.265954	53	0.778820836	38	1.020256753	39	2.109125	85	0.982684942	0.045288903	normal	0.975443755	-0.219930672	normal	0.742440899	0.658219625	normal	0.801265235	0.255484834	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; C2H2-type zinc finger;; C2H2 type zinc-finger (2 copies)"	Hypermethylated in cancer 1 protein GN=HIC1 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: hypermethylated in cancer 1 protein isoform X1 [Bubalus bubalis]
ENSG00000177380(PPFIA3)	--	5.455974343	305	2.891720653	201	3.877304112	272	2.30362477	113	2.739418	162	1.906783299	129	4.11E-09	-1.450799816	down	0.89815844	-0.329857862	normal	9.31E-05	-1.075640483	down	0.001313192	-0.965869661	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Liprin-alpha-3 GN=PPFIA3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: liprin-alpha-3 isoform 1 [Ceratotherium simum simum]
ENSG00000177383(MAGEF1)	--	19.3869	520	16.0879	448	18.888	520	23.9795	654	19.5277	523	20.7063	555	0.892631768	0.299157182	normal	0.946666219	0.201256389	normal	0.969231479	0.085444142	normal	0.402102147	0.197445866	normal	--	--	--	--	--	[S]	Function unknown	MAGE family	Melanoma-associated antigen F1 GN=MAGEF1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: melanoma-associated antigen F1-like [Bos mutus] 
ENSG00000177409(SAMD9L)	--	0.84878683	114	0.596979443	73	0.670529492	69	1.523465107	182	1.21937281	162	0.90306071	125	0.374210754	0.637220201	normal	0.001443319	1.112738737	up	0.158345612	0.835177944	normal	0.008594297	0.850759221	normal	--	--	--	--	--	--	--	--	Sterile alpha motif domain-containing protein 9-like GN=SAMD9L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: sterile alpha motif domain-containing protein 9-like [Galeopterus variegatus] 
ENSG00000177425(PAWR)	--	18.22713	1731	17.23582122	1797	21.69168427	1990	28.46369884	2761	27.456789	2559	27.78704414	2414	0.022131912	0.642297768	normal	0.438547554	0.488217243	normal	0.949310291	0.270179112	normal	0.0015294	0.465680276	normal	--	--	--	--	--	--	--	--	PRKC apoptosis WT1 regulator protein GN=PAWR OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: PRKC apoptosis WT1 regulator protein [Orycteropus afer afer]
ENSG00000177426(TGIF1)	--	80.70520377	1990	95.97902693	2271	76.82804115	2083	67.48811601	1645	70.98030415	1833	88.72015687	2306	0.918184824	-0.305253416	normal	0.900938154	-0.330302124	normal	0.98208494	0.138342736	normal	0.565217571	-0.15356745	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Homeobox protein TGIF1 GN=TGIF1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	Homeobox protein TGIF1 [Pteropus alecto]
ENSG00000177427(MIEF2)	--	10.69033077	322	7.700490364	330	11.92187704	353	9.1220586	373	8.59563594	274	11.010827	348	0.950946899	0.180482039	normal	0.906210443	-0.288264563	normal	0.968441486	-0.028748276	normal	0.93492335	-0.035832571	normal	--	--	--	--	--	--	--	Mab-21 protein	Mitochondrial dynamics protein MID49 GN=MIEF2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: mitochondrial dynamic protein MID49 isoform X1 [Equus caballus] 
ENSG00000177432(NAP1L5)	--	1.07858	47	0.874369	39	1.46784	65	1.72733	77	1.39785	61	1.74852	77	0.782170755	0.664250828	normal	0.886023872	0.605012769	normal	0.964816665	0.23118024	normal	0.352150257	0.489308227	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11283|7.1273e-56|pps:100995943|NAP1L5; nucleosome assembly protein 1-like 5; K11283 nucleosome assembly protein 1-like 5 (A)	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Nucleosome assembly protein (NAP)	Nucleosome assembly protein 1-like 5 GN=NAP1L5 OS=Homo sapiens (Human) PE=2 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nucleosome assembly protein 1-like 5 [Pantholops hodgsonii]
ENSG00000177453(NIM1K)	--	0.134484264	8	0.1061987	6	0.1946233	10	0.514467054	25	0.3531623	17	0.082220248	4	0.711215944	1.44899413	normal	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16310|0|hsa:167359|NIM1K, NIM1; NIM1 serine/threonine protein kinase (EC:2.7.11.1); K16310 serine/threonine-protein kinase NIM1 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase NIM1 GN=NIM1K OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase NIM1-like [Ceratotherium simum simum]
ENSG00000177459(ERICH5)	--	1.295602	56	1.429028	59	1.409612	50	3.7023	164	3.33403	147	3.189424	133	1.93E-06	1.494322856	up	0.000230267	1.274232524	up	9.46E-05	1.376626316	up	1.57E-05	1.406008422	up	--	--	--	--	--	--	--	Domain of unknown function (DUF4573)	Glutamate-rich protein 5 GN=ERICH5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: glutamate-rich protein 5 [Galeopterus variegatus]
ENSG00000177463(NR2C2)	--	15.04384754	1586	18.631746	1683	13.256693	1508	13.095644	1579	12.1033044	1668	19.277986	1755	0.984187194	-0.037177768	normal	0.98446963	-0.034311476	normal	0.965021924	0.210347449	normal	0.867131421	0.045383459	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08544|0|mcf:102121247|NR2C2; nuclear receptor subfamily 2, group C, member 2; K08544 testicular receptor 4 (A)"	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Nuclear receptor subfamily 2 group C member 2 GN=NR2C2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor subfamily 2 group C member 2 isoform X1 [Orycteropus afer afer]
ENSG00000177465(ACOT4)	--	1.146036	44	0.745143	29	1.008624648	38	1.557829	60	2.046522	78	1.243411	48	0.95328934	0.404491979	normal	0.008379406	1.361095666	up	0.970416107	0.317479084	normal	0.16012779	0.723317236	normal	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	K01068|0|ptr:453018|ACOT4; acyl-CoA thioesterase 4; K01068 acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] (A)	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040)	--	--	BAAT / Acyl-CoA thioester hydrolase C terminal;; Acyl-CoA thioester hydrolase/BAAT N-terminal region;; Dienelactone hydrolase family;; Alpha/beta hydrolase family	Acyl-coenzyme A thioesterase 4 GN=ACOT4 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: acyl-coenzyme A thioesterase 4 [Odobenus rosmarus divergens]
ENSG00000177469(PTRF)	--	171.700598	13834	174.0940643	14366	196.1210691	16245	214.8220891	17369	174.4830487	14002	153.3170383	12418	0.983207867	0.297434537	normal	0.996867348	-0.058445834	normal	0.926857191	-0.395812073	normal	0.900681346	-0.043452808	normal	--	--	--	--	--	--	--	PTRF/SDPR family	Polymerase I and transcript release factor OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: polymerase I and transcript release factor isoform 1 [Odobenus rosmarus divergens]
ENSG00000177479(ARIH2)	--	22.81305545	1579	21.2143098	1650	22.69111046	1650	22.61508806	1703	22.38045623	1690	24.56636609	1622	0.983085862	0.07816176	normal	0.984723115	0.013118784	normal	0.984646213	-0.032953184	normal	0.955474803	0.018369676	normal	--	--	--	K11969|0|pps:100971470|ARIH2; ariadne RBR E3 ubiquitin protein ligase 2; K11969 ariadne-2 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	IBR domain	E3 ubiquitin-protein ligase ARIH2 GN=ARIH2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase ARIH2 isoform X1 [Oryctolagus cuniculus]
ENSG00000177483(RBM44)	--	0.093170332	7	0.16201329	8	0.04580941	2	0.066284411	4	0.094104839	6	0.026348961	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 44 GN=RBM44 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: RNA-binding protein 44 [Ceratotherium simum simum]
ENSG00000177485(ZBTB33)	--	12.611523	991	13.408826	1045	13.41640229	1026	11.847936	937	11.25651553	882	12.20404	964	0.973945622	-0.111490469	normal	0.929099583	-0.265659885	normal	0.975712077	-0.098067969	normal	0.451619069	-0.15896284	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10507|0|hsa:10009|ZBTB33, ZNF-kaiso, ZNF348; zinc finger and BTB domain containing 33; K10507 zinc finger and BTB domain-containing protein 33 (A)"	--	[R]	General function prediction only	BTB/POZ domain;; Zinc-finger double domain	Transcriptional regulator Kaiso GN=ZBTB33 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: transcriptional regulator Kaiso [Tupaia chinensis]
ENSG00000177494(ZBED2)	--	0	0	0	0	0.0853961	3	0.542716	25	0.770728	35	0.239976	11	0.00023007	4.095834758	up	4.39E-07	4.583345439	up	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	BED zinc finger	Zinc finger BED domain-containing protein 2 GN=ZBED2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger BED domain-containing protein 2 [Canis lupus familiaris]
ENSG00000177508(IRX3)	--	2.189368	105	3.122189	135	2.319036593	103	2.32320402	109	1.716405423	87	2.855728636	108	0.970271404	0.022779398	normal	0.509594869	-0.646205991	normal	0.969512221	0.059245977	normal	0.705192102	-0.195778709	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox KN domain;; Homeobox domain	Iroquois-class homeodomain protein IRX-3 GN=IRX3 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: iroquois-class homeodomain protein IRX-3 [Trichechus manatus latirostris]
ENSG00000177519(RPRM)	--	0.0483163	1	0	0	0.0453813	0	0.0475232	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10128|2.06073e-73|ssc:100738077|protein reprimo-like; K10128 reprimo, TP53-dependent G2 arrest mediator candidate (A)"	p53 signaling pathway (ko04115)	--	--	--	Protein reprimo GN=RPRM OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	protein reprimo [Bos taurus] 
ENSG00000177542(SLC25A22)	--	17.99578881	790	14.6530163	695	18.7102819	816	16.48506843	695	14.26393535	609	10.3955796	482	0.947880858	-0.215225264	normal	0.947009625	-0.211505232	normal	0.002158489	-0.765958667	normal	0.042659247	-0.387592446	normal	--	--	--	"K15107|0|hsa:79751|SLC25A22, EIEE3, GC1, NET44; solute carrier family 25 (mitochondrial carrier: glutamate), member 22; K15107 solute carrier family 25 (mitochondrial glutamate transporter), member 18/22 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial glutamate carrier 1 GN=SLC25A22 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial glutamate carrier 1 [Galeopterus variegatus] 
ENSG00000177548(RABEP2)	--	4.61202596	250	7.266727	379	4.92691198	313	5.638547803	325	6.288034061	358	6.290489335	348	0.858819076	0.345810966	normal	0.963203116	-0.103240877	normal	0.958180551	0.143973223	normal	0.748610372	0.109201635	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: growth factor activity (GO:0008083);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Rabaptin;; Rabaptin-like protein	Rab GTPase-binding effector protein 2 GN=RABEP2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab GTPase-binding effector protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000177556(ATOX1)	--	127.6981092	546	120.1589676	527	116.571962	506	150.1592804	689	153.7805475	657	144.9846318	629	0.888300827	0.304007839	normal	0.896939354	0.295902045	normal	0.887430881	0.304812588	normal	0.135600094	0.301280771	normal	--	--	--	K07213|8.62802e-31|ptr:743743|ATOX1; antioxidant 1 copper chaperone; K07213 copper chaperone (A)	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Heavy-metal-associated domain	Copper transport protein ATOX1 GN=ATOX1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: copper transport protein ATOX1 [Ochotona princeps]
ENSG00000177565(TBL1XR1)	--	13.46357447	1162	14.78511775	1179	16.44895178	1107	15.53388882	1350	18.13075974	1427	16.45948272	1495	0.966282132	0.185289627	normal	0.943582456	0.253698895	normal	0.649013373	0.424697765	normal	0.088732924	0.288177998	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K04508|0|pps:100992638|TBL1XR1; transducin (beta)-like 1 X-linked receptor 1; K04508 transducin (beta)-like 1 (A)	Wnt signaling pathway (ko04310)	[B]	Chromatin structure and dynamics	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A;; LisH;; Anaphase-promoting complex subunit 4 WD40 domain"	F-box-like/WD repeat-containing protein TBL1XR1 GN=TBL1XR1 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: F-box-like/WD repeat-containing protein TBL1XR1 [Orycteropus afer afer]
ENSG00000177570(SAMD12)	--	3.090002753	124	1.502310537	73	2.2614456	121	2.75845728	83	3.46223141	107	1.189545885	89	0.65601593	-0.600824136	normal	0.825554136	0.521248328	normal	0.870072708	-0.444911886	normal	0.689714633	-0.209155798	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: sequence-specific DNA binding (GO:0043565);; 	--	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Sterile alpha motif (SAM)/Pointed domain	Sterile alpha motif domain-containing protein 12 GN=SAMD12 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: sterile alpha motif domain-containing protein 12 isoform 1 [Orcinus orca]
ENSG00000177575(CD163)	--	0.648581915	98	0.631890798	99	0.7174846	110	0.863589974	130	0.605930878	77	0.805712226	123	0.909222899	0.371751469	normal	0.92354075	-0.377440527	normal	0.963132167	0.150900565	normal	0.896556396	0.082823407	normal	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	"K06545|0|hsa:9332|CD163, M130, MM130; CD163 molecule; K06545 CD163 antigen (A)"	--	--	--	Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	Soluble CD163 (Precursor) GN=CD163 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: scavenger receptor cysteine-rich type 1 protein M130 [Trichechus manatus latirostris]
ENSG00000177576(C18orf32)	--	842.8341056	7570	820.4944667	7254	834.6558784	7482	932.7107872	8577	887.1705125	7972	773.5944469	7157	0.992878176	0.149319073	normal	0.993639143	0.114715589	normal	0.994583263	-0.072345476	normal	0.801164044	0.066119054	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4512)	UPF0729 protein C18orf32 GN=C18orf32 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	UPF0729 protein C18orf32 homolog [Bos taurus] 
ENSG00000177595(PIDD1)	--	6.7612123	361	6.420550001	350	7.530258266	413	6.058654239	323	5.693791	301	6.470080922	347	0.948394071	-0.190439465	normal	0.931766128	-0.237908288	normal	0.922221276	-0.258463673	normal	0.388702871	-0.231828287	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; Biological Process: apoptotic process (GO:0006915);; Biological Process: cellular response to DNA damage stimulus (GO:0006974);; Biological Process: signal transduction (GO:0007165);; 	"K10130|0|hsa:55367|PIDD1, LRDD, PIDD; p53-induced death domain protein 1; K10130 leucine-rich repeats and death domain-containing protein (A)"	NF-kappa B signaling pathway (ko04064);; p53 signaling pathway (ko04115)	[M]	Cell wall/membrane/envelope biogenesis	Leucine Rich repeats (2 copies);; Peptidase S68;; Leucine rich repeat;; Death domain;; Leucine Rich Repeat;; ZU5 domain	p53-induced death domain-containing protein 1 GN=PIDD1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: p53-induced protein with a death domain isoform X2 [Galeopterus variegatus]
ENSG00000177599(ZNF491)	--	0	0	0	0	0	0	0.022353713	1	0	0	0.147079084	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 491 GN=ZNF491 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 709-like [Odobenus rosmarus divergens]
ENSG00000177600(RPLP2)	--	706.602503	5986	656.0744451	5693	673.5482688	5917	776.4502755	6793	716.7227816	6115	662.4846575	5737	0.991279374	0.151587772	normal	0.99317329	0.081715894	normal	0.993816533	-0.052847101	normal	0.813067828	0.061859575	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02943|3.02523e-35|chx:102179549|RPLP2; ribosomal protein, large, P2; K02943 large subunit ribosomal protein LP2 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	60s Acidic ribosomal protein	60S acidic ribosomal protein P2 GN=RPLP2 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S acidic ribosomal protein P2 [Trichechus manatus latirostris]
ENSG00000177602(GSG2)	--	6.55856	451	6.875	477	7.45247	526	6.80608	466	6.4246	413	6.30386	411	0.970773614	0.016315578	normal	0.936120406	-0.228494717	normal	0.811610622	-0.363031964	normal	0.444930992	-0.194043482	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	"K16315|0|hsa:83903|GSG2, HASPIN; germ cell associated 2 (haspin) (EC:2.7.11.1); K16315 serine/threonine-protein kinase haspin [EC:2.7.11.1] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Domain of unknown function (DUF3635);; Protein kinase domain	Serine/threonine-protein kinase haspin GN=GSG2 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase haspin [Balaenoptera acutorostrata scammoni]
ENSG00000177606(JUN)	--	25.809	1632	23.4829	1524	26.9098	1759	55.424	3548	51.5344	3272	26.2782	1682	6.72E-09	1.088820877	up	1.98E-08	1.080134604	up	0.983895885	-0.072805202	normal	0.137802509	0.76774011	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04448|7.37474e-174|ptr:456893|JUN; jun proto-oncogene; K04448 transcription factor AP-1 (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; cAMP signaling pathway (ko04024);; Wnt signaling pathway (ko04310);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Toll-like receptor signaling pathway (ko04620);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Oxytocin signaling pathway (ko04921);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis B (ko05161);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Colorectal cancer (ko05210);; Renal cell carcinoma (ko05211);; Choline metabolism in cancer (ko05231);; Inflammatory bowel disease (IBD) (ko05321);; Rheumatoid arthritis (ko05323)	[K]	Transcription	Jun-like transcription factor;; bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Transcription factor AP-1 GN=JUN OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor AP-1 [Elephantulus edwardii]
ENSG00000177613(CSTF2T)	--	12.7541	949	12.604	947	12.4205	921	14.2585	1066	13.1222	971	12.1619	905	0.971504673	0.136686311	normal	0.97850915	0.014657197	normal	0.978135842	-0.033519282	normal	0.887671679	0.040893017	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: mRNA 3'-end processing (GO:0031124);; 	"K14407|0|hsa:23283|CSTF2T, CstF-64T; cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant; K14407 cleavage stimulation factor subunit 2 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"Hinge domain of cleavage stimulation factor subunit 2;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Transcription termination and cleavage factor C-terminal;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Cleavage stimulation factor subunit 2 tau variant GN=CSTF2T OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: cleavage stimulation factor subunit 2 tau variant-like isoform 4 [Tursiops truncatus]
ENSG00000177614(PGBD5)	--	0.105607406	12	0.107865621	6	0.046859683	9	0.349916384	19	0.331673834	27	0.146405154	24	--	--	--	0.190128747	1.905559034	normal	0.837534376	1.271666338	normal	--	--	--	--	--	--	--	--	--	--	Transposase IS4	PiggyBac transposable element-derived protein 5 GN=PGBD5 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: piggyBac transposable element-derived protein 5 [Oryctolagus cuniculus]
ENSG00000177628(GBA)	--	64.184324	2685	69.368688	2965	66.412148	2766	56.362605	2360	46.818959	1975	75.039694	3141	0.971772005	-0.216835024	normal	0.061613232	-0.607223733	normal	0.981674401	0.175041482	normal	0.565987966	-0.191308784	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K01201|0|hsa:2629|GBA, GBA1, GCB, GLUC; glucosidase, beta, acid (EC:3.2.1.45); K01201 glucosylceramidase [EC:3.2.1.45] (A)"	Other glycan degradation (ko00511);; Sphingolipid metabolism (ko00600);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	O-Glycosyl hydrolase family 30	Glucosylceramidase (Precursor) GN=GBA OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: glucosylceramidase isoform X1 [Galeopterus variegatus]
ENSG00000177646(ACAD9)	--	13.26410832	629	14.71070799	706	15.08150457	722	13.13480035	625	13.68630604	644	11.9568	568	0.973460485	-0.039938223	normal	0.96252108	-0.153689206	normal	0.822564362	-0.353562317	normal	0.413954286	-0.184501897	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K15980|0|ptr:460679|ACAD9; acyl-CoA dehydrogenase family, member 9; K15980 acyl-CoA dehydrogenase family member 9 [EC:1.3.99.-] (A)"	--	[I]	Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, middle domain;; Acyl-CoA dehydrogenase, C-terminal domain"	"Acyl-CoA dehydrogenase family member 9, mitochondrial (Precursor) GN=ACAD9 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: acyl-CoA dehydrogenase family member 9, mitochondrial [Galeopterus variegatus]"
ENSG00000177663(IL17RA)	--	3.918517984	679	3.240900407	571	3.595541895	631	3.3997876	589	3.551862797	613	3.0133444	526	0.936943576	-0.235403666	normal	0.969952684	0.080763306	normal	0.916328868	-0.270158452	normal	0.565987966	-0.143814192	normal	--	--	--	K05164|0|pps:100967401|IL17RA; interleukin 17 receptor A; K05164 interleukin 17 receptor (A)	Cytokine-cytokine receptor interaction (ko04060)	--	--	SEFIR domain	Interleukin-17 receptor A (Precursor) GN=IL17RA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-17 receptor A [Ceratotherium simum simum]
ENSG00000177666(PNPLA2)	--	37.73453	1519	25.34245	1020	33.78456	1395	32.965465	1322	39.5254	1584	32.63327	1321	0.955236393	-0.23098126	normal	0.053636441	0.61284202	normal	0.980450905	-0.086829353	normal	0.830156026	0.0827943	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K16816|0|hsa:57104|PNPLA2, 1110001C14Rik, ATGL, PEDF-R, TTS-2.2, TTS2, iPLA2zeta; patatin-like phospholipase domain containing 2 (EC:3.1.1.3); K16816 patatin-like phospholipase domain-containing protein 2 [EC:3.1.1.3] (A)"	Glycerolipid metabolism (ko00561)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Patatin-like phospholipase	Patatin-like phospholipase domain-containing protein 2 GN=PNPLA2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: patatin-like phospholipase domain-containing protein 2 [Pteropus alecto] 
ENSG00000177669(MBOAT4)	--	0	0	0.0450037	1	0.26819	5	0.0455667	1	0.0894901	1	0.0457108	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	"MBOAT, membrane-bound O-acyltransferase family"	Ghrelin O-acyltransferase GN=MBOAT4 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ghrelin O-acyltransferase [Equus caballus]
ENSG00000177674(AGTRAP)	--	49.13468743	737	47.02335875	708	47.61035142	732	66.06057555	1012	66.2382115	985	75.18628395	1155	0.633911267	0.425880104	normal	0.546528825	0.454122049	normal	0.023548843	0.648610081	normal	0.001166051	0.513142538	normal	--	--	Biological Process: angiotensin-activated signaling pathway (GO:0038166);; 	--	--	--	--	"Angiotensin II, type I receptor-associated protein (AGTRAP)"	Type-1 angiotensin II receptor-associated protein GN=AGTRAP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: type-1 angiotensin II receptor-associated protein isoform X1 [Tupaia chinensis]
ENSG00000177679(SRRM3)	--	2.915370994	229	2.176159205	174	1.922258	160	3.049033	246	3.913155	313	1.733361	139	0.964942722	0.072012258	normal	0.009212901	0.820261601	normal	0.951275396	-0.209155634	normal	0.677559263	0.287425461	normal	--	--	--	--	--	[A]	RNA processing and modification	Serine/arginine repetitive matrix protein C-terminus;; cwf21 domain	Serine/arginine repetitive matrix protein 3 GN=SRRM3 OS=Homo sapiens (Human) PE=2 SV=4	A	RNA processing and modification	PREDICTED: serine/arginine repetitive matrix protein 3-like [Leptonychotes weddellii]
ENSG00000177683(THAP5)	--	13.6224727	628	13.749634	632	13.66580042	654	10.581109	523	12.23538509	585	11.45856114	552	0.897161565	-0.293996354	normal	0.96462452	-0.132584629	normal	0.92789714	-0.25227803	normal	0.300465686	-0.226323302	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 5 GN=THAP5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: THAP domain-containing protein 5 isoform X1 [Galeopterus variegatus]
ENSG00000177685(CRACR2B)	--	1.81546675	40	3.267621591	59	1.802575822	43	1.903681131	38	1.518593854	30	1.411918148	39	0.981452919	-0.100857483	normal	0.483462394	-0.961958343	normal	0.979555493	-0.14383993	normal	0.511207687	-0.429827613	normal	--	--	--	"K17199|0|hsa:283229|CRACR2B, EFCAB4A; calcium release activated channel regulator 2B; K17199 Ras and EF-hand domain-containing protein (A)"	--	--	--	EF-hand domain	EF-hand calcium-binding domain-containing protein 4A GN=CRACR2B OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: EF-hand calcium-binding domain-containing protein 4A isoform X1 [Equus caballus]
ENSG00000177688(SUMO4)	--	0.191499	3	0.190314	3	0.063276	0	0.063496	1	0.248982	3	0.12724	2	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K12160|9.38207e-65|hsa:387082|SUMO4, IDDM5, SMT3H4, SUMO-4, dJ281H8.4; small ubiquitin-like modifier 4; K12160 small ubiquitin-related modifier (A)"	RNA transport (ko03013)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin family	Small ubiquitin-related modifier 4 (Precursor) GN=SUMO4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: small ubiquitin-related modifier 2 [Galeopterus variegatus]
ENSG00000177692(DNAJC28)	--	0.697202761	18	0.489600348	13	0.267580211	7	0.254836214	8	0.272491746	9	0.24127712	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF1992);; DnaJ domain	DnaJ homolog subfamily C member 28 GN=DNAJC28 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 28 [Odobenus rosmarus divergens]
ENSG00000177694(NAALADL2)	--	0.019279372	3	0	0	0	0	0.02554801	4	0.309089882	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[OPR]	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism;; General function prediction only"	Peptidase family M28	Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 GN=NAALADL2 OS=Homo sapiens (Human) PE=1 SV=3	OP	"Posttranslational modification, protein turnover, chaperones;; Inorganic ion transport and metabolism"	PREDICTED: inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X1 [Oryctolagus cuniculus]
ENSG00000177697(CD151)	--	267.8938615	6555	264.5593455	6819	273.0184038	6951	365.0316471	9143	360.5699319	8883	285.8311598	7179	0.756023081	0.449150077	normal	0.93670785	0.359990119	normal	0.994849474	0.038262719	normal	0.106596757	0.288659935	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06537|8.98431e-155|ggo:101147045|CD151; CD151 antigen; K06537 CD151 antigen (A)	--	[R]	General function prediction only	Tetraspanin family	CD151 antigen GN=CD151 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: CD151 antigen [Galeopterus variegatus]
ENSG00000177700(POLR2L)	--	172.166	2214	208.672	2719	204.131	2708	189.888	2505	165.968	2131	180.768	2367	0.982056816	0.147227026	normal	0.848272906	-0.372737295	normal	0.975054467	-0.202338514	normal	0.464227679	-0.147090549	normal	[K]	Transcription	--	"K03007|2.50278e-42|lcm:102351470|DNA-directed RNA polymerases I, II, and III subunit RPABC5-like; K03007 DNA-directed RNA polymerases I, II, and III subunit RPABC5 (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623)	[K]	Transcription	RNA polymerases N / 8 kDa subunit	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 GN=POLR2L OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	PREDICTED: translation initiation factor IF-2-like [Ochotona princeps]
ENSG00000177706(FAM20C)	--	23.0569128	977	21.86181022	1028	21.92101074	1031	18.29701818	821	18.3063895	745	17.12274988	759	0.91537635	-0.281325234	normal	0.419490325	-0.485112254	normal	0.546179072	-0.449392614	normal	0.014188003	-0.406359188	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1193)	Extracellular serine/threonine protein kinase FAM20C (Precursor) GN=FAM20C OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: extracellular serine/threonine protein kinase FAM20C [Tupaia chinensis]
ENSG00000177707(NECTIN3)	--	25.750649	2761	29.710138	2990	26.66875707	2747	37.9493238	3860	36.94060431	3633	39.94667321	3917	0.624203812	0.452363929	normal	0.965246261	0.259470109	normal	0.382466397	0.503367531	normal	0.008084022	0.403833185	normal	--	--	--	K06592|0|nle:100579224|PVRL3; poliovirus receptor-related 3; K06592 poliovirus receptor-related protein 3 (A)	Cell adhesion molecules (CAMs) (ko04514);; Adherens junction (ko04520)	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Nectin-3 (Precursor) GN=PVRL3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: poliovirus receptor-related protein 3 isoform 1 [Odobenus rosmarus divergens]
ENSG00000177710(SLC35G5)	--	0.0512662	1	0.551997	11	0	0	0.0509227	1	0.0500937	0	0.203034	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	EamA-like transporter family	Solute carrier family 35 member G5 GN=SLC35G5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: solute carrier family 35 member G3-like [Mustela putorius furo]
ENSG00000177721(ANXA2R)	--	1.512403	32	1.098284	21	0.900238	17	1.706439	33	2.104122	43	1.341578	30	0.984292609	0.012949607	normal	0.741117218	0.963148114	normal	0.945213276	0.75967748	normal	0.401096861	0.576725877	normal	--	--	Molecular Function: receptor activity (GO:0004872);; 	--	--	--	--	--	Annexin-2 receptor GN=ANXA2R OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: annexin-2 receptor-like [Ceratotherium simum simum] 
ENSG00000177728(TMEM94)	--	25.00808107	1967	31.38139043	2042	30.37765866	2003	25.7038395	1949	31.07569764	2205	33.73894055	2523	0.986166521	-0.044060556	normal	0.984953363	0.089305576	normal	0.909018484	0.324467607	normal	0.53086332	0.130942145	normal	--	--	--	--	--	[S]	Function unknown	"Cation transporting ATPase, C-terminus"	Uncharacterized protein KIAA0195 GN=KIAA0195 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA0195 homolog isoform X2 [Equus przewalskii]
ENSG00000177731(FLII)	--	62.45433472	5488	71.49939073	6261	69.63622876	5910	72.66170917	6356	67.786067	6035	72.551791	6286	0.988649013	0.180959274	normal	0.993543015	-0.074447571	normal	0.993554554	0.080672681	normal	0.822459709	0.059600534	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Gelsolin repeat;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Protein flightless-1 homolog GN=FLII OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein flightless-1 homolog isoform X1 [Felis catus]
ENSG00000177732(SOX12)	--	34.2128	2957	30.9209	2706	31.0549	2737	22.0174	1905	25.7721	2223	26.012	2270	0.012366392	-0.664741382	normal	0.932544452	-0.304892108	normal	0.949003151	-0.278025637	normal	0.005886643	-0.413440028	normal	--	--	--	K09268|3.58503e-49|ggo:101132208|SOX12; transcription factor SOX-12; K09268 transcription factor SOX4/11/12 (SOX group C) (A)	--	[K]	Transcription	HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-12 GN=SOX12 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: transcription factor SOX-12 [Ceratotherium simum simum]
ENSG00000177733(HNRNPA0)	--	30.9609	3764	29.8046	3694	29.7134	3593	36.4286	4511	41.3745	5026	32.9297	4010	0.977413111	0.230262449	normal	0.783882101	0.42265138	normal	0.987055292	0.150062046	normal	0.111162692	0.272295171	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12894|2.43723e-116|ggo:101147339|HNRNPA0; heterogeneous nuclear ribonucleoprotein A0; K12894 heterogeneous nuclear ribonucleoprotein A0 (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Heterogeneous nuclear ribonucleoprotein A0 GN=HNRNPA0 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"PREDICTED: heterogeneous nuclear ribonucleoprotein A0, partial [Camelus bactrianus]"
ENSG00000177807(KCNJ10)	--	0.088470663	5	0.024847017	2	0.037139631	2	0.160119114	2	0	0	0.014404701	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05003|0|ptr:457431|KCNJ10; potassium inwardly-rectifying channel, subfamily J, member 10; K05003 potassium inwardly-rectifying channel subfamily J member 10 (A)"	Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	ATP-sensitive inward rectifier potassium channel 10 GN=KCNJ10 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: ATP-sensitive inward rectifier potassium channel 10 [Sus scrofa]
ENSG00000177830(CHID1)	--	32.80615589	1155	32.12219967	1137	31.54145777	1160	31.64129633	1117	34.75790046	1147	28.91702852	1004	0.97871376	-0.078989072	normal	0.980609304	-0.008781792	normal	0.954775963	-0.216353514	normal	0.667064915	-0.100461458	normal	--	--	Biological Process: carbohydrate metabolic process (GO:0005975);; 	K17525|0|mcf:101865162|hypothetical protein; K17525 chitinase domain-containing protein 1 (A)	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 18	Chitinase domain-containing protein 1 (Precursor) GN=CHID1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: chitinase domain-containing protein 1 isoformX3 [Equus caballus]
ENSG00000177853(ZNF518A)	--	8.448765725	1196	9.304390833	1286	8.3010204	1105	7.559201475	1041	8.040515507	1108	10.20323846	1441	0.949876907	-0.230761504	normal	0.949522069	-0.236059928	normal	0.79708317	0.374282706	normal	0.964739885	-0.019232102	normal	--	--	--	--	--	[R]	General function prediction only	Zinc-finger double domain	Zinc finger protein 518A GN=ZNF518A OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 518A [Equus przewalskii] 
ENSG00000177854(TMEM187)	--	14.29614452	306	11.01447215	253	13.464211	270	8.932343	193	10.8257	214	9.61082571	214	0.071668699	-0.69135033	normal	0.925721947	-0.261252906	normal	0.873516981	-0.341486621	normal	0.09865505	-0.437649483	normal	--	--	--	--	--	--	--	TMEM187 protein family	Transmembrane protein 187 GN=TMEM187 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein PANDA_018917 [Ailuropoda melanoleuca]
ENSG00000177868(SVBP)	--	3.691645	89	4.3614	98	2.96328	73	5.9825156	127	3.966286	104	6.490029	121	0.839030952	0.475220384	normal	0.968522513	0.063354234	normal	0.43524056	0.70922006	normal	0.328788737	0.415193094	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 23 GN=CCDC23 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 23 [Orcinus orca] 
ENSG00000177875(CCDC184)	--	4.13587	173	3.548	151	4.35454	186	4.17485	175	3.49499	146	4.29808	181	0.967228623	-0.014124658	normal	0.965082381	-0.069300846	normal	0.96634294	-0.047215197	normal	0.940882927	-0.043700229	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 184 GN=CCDC184 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C12orf68 homolog [Mustela putorius furo] 
ENSG00000177879(AP3S1)	--	35.14283	818	35.24351931	917	34.8802	798	37.07251093	965	33.71272	817	35.028486	898	0.953884695	0.207237159	normal	0.958969212	-0.187684072	normal	0.964881375	0.161746152	normal	0.828193378	0.059736461	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K12399|6.78562e-140|pale:102884832|AP3S1; adaptor-related protein complex 3, sigma 1 subunit; K12399 AP-3 complex subunit sigma (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	AP-3 complex subunit sigma-1 GN=AP3S1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-3 complex subunit sigma-1-like [Leptonychotes weddellii]
ENSG00000177885(GRB2)	--	67.61117343	3269	62.44314128	3202	65.06895933	3335	69.99895433	3685	70.61251362	3737	60.0318566	3294	0.986835173	0.14192013	normal	0.979960425	0.201392584	normal	0.990806919	-0.026125728	normal	0.628037851	0.106604019	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K04364|5.84427e-162|umr:103665736|GRB2; growth factor receptor-bound protein 2; K04364 growth factor receptor-binding protein 2 (A)	MAPK signaling pathway (ko04010);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; FoxO signaling pathway (ko04068);; PI3K-Akt signaling pathway (ko04151);; Dorso-ventral axis formation (ko04320);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; Gap junction (ko04540);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Alcoholism (ko05034);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Renal cell carcinoma (ko05211);; Endometrial cancer (ko05213);; Glioma (ko05214);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Non-small cell lung cancer (ko05223);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; SH2 domain	Growth factor receptor-bound protein 2 GN=GRB2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: growth factor receptor-bound protein 2 isoform 1 [Dasypus novemcinctus] 
ENSG00000177888(ZBTB41)	--	4.00534	497	4.78785484	593	4.73814	572	4.711966	596	4.818517	603	5.0897556	638	0.937266241	0.230582603	normal	0.973003919	0.00269253	normal	0.962566005	0.148876976	normal	0.638667546	0.123495712	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10513|0|pps:100996126|ZBTB41; zinc finger and BTB domain containing 41; K10513 zinc finger and BTB domain-containing protein 41 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; BTB/POZ domain;; Zinc-finger of C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 41 GN=ZBTB41 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 41 [Galeopterus variegatus]
ENSG00000177889(UBE2N)	--	45.98649103	1609	54.05129	1628	54.95245	1549	77.9191	2112	62.93659	1896	50.64384	1551	0.845020958	0.361311324	normal	0.969398849	0.19826092	normal	0.984404129	-0.006423633	normal	0.336324248	0.193831926	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 N GN=UBE2N OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 N-like [Ovis aries]
ENSG00000177917(ARL6IP6)	--	19.4991	686	18.5387	671	18.8514	674	13.8473	498	11.9359	421	10.6069	376	0.40301974	-0.491596624	normal	0.018551444	-0.691931448	normal	0.000416052	-0.847723961	normal	9.96E-05	-0.671312243	normal	--	--	--	--	--	--	--	Haemopoietic lineage transmembrane helix	ADP-ribosylation factor-like protein 6-interacting protein 6 GN=ARL6IP6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ADP-ribosylation factor-like protein 6-interacting protein 6 [Pantholops hodgsonii]
ENSG00000177932(ZNF354C)	--	2.383373817	237	1.636422968	165	1.811426246	180	1.973047607	217	1.912189588	201	2.251927607	233	0.955990822	-0.156960376	normal	0.931471892	0.261131543	normal	0.865980969	0.361366132	normal	0.725513278	0.140508238	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:30832|ZNF354C, KID3; zinc finger protein 354C; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; Rapsyn N-terminal myristoylation and linker region"	Zinc finger protein 354C GN=ZNF354C OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 99-like [Odobenus rosmarus divergens]
ENSG00000177943(MAMDC4)	--	1.377668844	104	1.343892749	103	1.170292212	91	0.655941773	48	0.59064023	43	1.3355335	99	0.015293418	-1.121308259	normal	0.003611372	-1.252304576	down	0.968596838	0.111493679	normal	0.149063632	-0.66850144	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	MAM domain;; Low-density lipoprotein receptor domain class A	Apical endosomal glycoprotein (Precursor) GN=UNQ3001/PRO9742 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: apical endosomal glycoprotein-like [Galeopterus variegatus]
ENSG00000177946(CENPBD1)	--	7.31758	399	5.53455	307	4.82292	267	6.11565	336	5.49068	298	5.01125	274	0.910656456	-0.27759317	normal	0.965108662	-0.064032711	normal	0.967094214	0.028883216	normal	0.755656779	-0.121984576	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Tc5 transposase DNA-binding domain;; CENP-B N-terminal DNA-binding domain	CENPB DNA-binding domain-containing protein 1 GN=CENPBD1 OS=Homo sapiens (Human) PE=2 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: CENPB DNA-binding domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000177947(ODF3)	--	0	0	0.146519	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sperm-tail PG-rich repeat	Outer dense fiber protein 3 GN=ODF3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: outer dense fiber protein 3 isoform X1 [Ursus maritimus]
ENSG00000177951(BET1L)	--	23.70945793	1015	19.50758936	860	22.34417568	967	24.79175794	1132	28.070086	1281	22.6189565	1004	0.973750499	0.126380764	normal	0.171342234	0.552634249	normal	0.978659685	0.045809721	normal	0.180085465	0.24447887	normal	--	--	--	--	--	--	--	--	Putative protein FAM157B GN=FAM157B OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: BET1-like protein [Dasypus novemcinctus]
ENSG00000177954(RPS27)	--	3605.952787	5914	3537.004654	5962	3312.00456	5859	3575.951909	6992	3611.66609	5970	3667.649598	6488	0.986482073	0.210688295	normal	0.994042433	-0.019487062	normal	0.991668913	0.138793871	normal	0.624851727	0.111663967	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02978|2.75297e-46|xma:102225077|40S ribosomal protein S27-like; K02978 small subunit ribosomal protein S27e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S27	40S ribosomal protein S27 GN=RPS27 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S27-like [Capra hircus]
ENSG00000177963(RIC8A)	--	37.07719604	2193	37.55328819	2279	37.197907	2278	50.467561	2981	42.53675503	2614	38.258761	2372	0.7472321	0.411810002	normal	0.978741933	0.176322345	normal	0.987613909	0.050012282	normal	0.219509999	0.217277302	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Guanine nucleotide exchange factor synembryn	Synembryn-A GN=RIC8A OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	Synembryn-A [Bos mutus]
ENSG00000177971(IMP3)	--	64.875205	1022	68.466369	1113	60.12690032	977	81.16490051	1304	80.118219	1262	77.675268	1235	0.884648925	0.320289268	normal	0.970177218	0.159627973	normal	0.871668565	0.329334739	normal	0.128259017	0.267008505	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Cellular Component: intracellular (GO:0005622);; Molecular Function: rRNA binding (GO:0019843);; 	"K14560|5.20306e-120|ptr:453760|IMP3; IMP3, U3 small nucleolar ribonucleoprotein; K14560 U3 small nucleolar ribonucleoprotein protein IMP3 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	S4 domain	U3 small nucleolar ribonucleoprotein protein IMP3 GN=IMP3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U3 small nucleolar ribonucleoprotein protein IMP3 [Ceratotherium simum simum] 
ENSG00000177981(ASB8)	--	16.52489432	348	7.685211806	304	13.76106724	381	11.97945298	472	14.98693174	482	15.53758619	488	0.727941315	0.407318058	normal	0.079003659	0.640982124	normal	0.83850894	0.347576737	normal	0.026615257	0.460462825	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10330|0|pps:100986163|ASB8; ankyrin repeat and SOCS box containing 8; K10330 ankyrin repeat and SOCS box protein 8 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SOCS box	Ankyrin repeat and SOCS box protein 8 GN=ASB8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 8 isoformX1 [Canis lupus familiaris] 
ENSG00000177984(LCN15)	--	0.195245	2	0	0	0	0	0.0927635	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lipocalin / cytosolic fatty-acid binding protein family	Lipocalin-15 (Precursor) GN=LCN15 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lipocalin-15 [Pteropus alecto]
ENSG00000177989(ODF3B)	--	2.695460097	23	0.932751094	10	1.754134028	12	3.59487044	37	6.043763934	59	3.8533834	34	0.950749167	0.62204439	normal	1.11E-05	2.37430247	up	0.446846587	1.386395444	normal	0.008018812	1.509033578	up	--	--	--	--	--	--	--	--	Outer dense fiber protein 3B GN=ODF3B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: outer dense fiber protein 3B [Loxodonta africana]
ENSG00000177990(DPY19L2)	--	2.887473628	192	3.135813917	196	3.288576082	189	4.278097466	225	2.570740037	137	4.678304167	289	0.949119883	0.196532541	normal	0.610267354	-0.533156003	normal	0.263482789	0.600478179	normal	0.813067828	0.153476576	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Q-cell neuroblast polarisation	Probable C-mannosyltransferase DPY19L2 GN=DPY19L2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: probable C-mannosyltransferase DPY19L2-like [Leptonychotes weddellii]
ENSG00000177992(SPATA31E1)	--	0	0	0.0088447	1	0	0	0	0	0.00869592	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM75 family;; Domain of unknown function (DUF4599)	Spermatogenesis-associated protein 31E1 GN=SPATA31E1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: spermatogenesis-associated protein 31E1 [Galeopterus variegatus]
ENSG00000177994(C2orf73)	--	0	0	0.093331502	3	0.137764906	2	0	0	0	0	0.0451532	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf73 GN=C2orf73 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C2orf73 homolog [Ceratotherium simum simum]
ENSG00000178015(GPR150)	--	0.122547	3	0.234963	6	0.0380958	0	0.120649	3	0.117776	2	0.0797906	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08434|0|pon:100434752|GPR150; G protein-coupled receptor 150; K08434 G protein-coupled receptor 150 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 150 GN=GPR150 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 150 [Vicugna pacos]
ENSG00000178026(LRRC75B)	--	4.984685002	112	4.131481	117	4.089605954	103	3.835888834	99	5.135696716	126	4.672044807	127	0.958911288	-0.205824894	normal	0.965891486	0.084436832	normal	0.939694512	0.290051066	normal	0.922328036	0.06379627	normal	--	--	--	--	--	--	--	--	Leucine-rich repeat-containing protein 75B GN=LRRC75B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: leucine-rich repeat-containing protein 75B, partial [Camelus bactrianus]"
ENSG00000178028(DMAP1)	--	9.409476457	435	11.259627	449	9.329342541	420	9.917166025	407	11.24394208	502	10.53718143	454	0.962224625	-0.12635734	normal	0.960722264	0.13910211	normal	0.96545302	0.103652479	normal	0.90591115	0.042954148	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	K11324|0|ptr:456517|DMAP1; DNA methyltransferase 1 associated protein 1; K11324 DNA methyltransferase 1-associated protein 1 (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	DNA methyltransferase 1-associated protein 1 (DMAP1)	DNA methyltransferase 1-associated protein 1 GN=DMAP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA methyltransferase 1-associated protein 1 [Equus caballus]
ENSG00000178031(ADAMTSL1)	--	0	0	0	0	0	0	0.224674792	21	0.303145151	13	0.39219264	16	0.002751624	3.860278256	up	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: peptidase activity (GO:0008233);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Immunoglobulin I-set domain;; Thrombospondin type 1 domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; PLAC (protease and lacunin) domain	ADAMTS-like protein 1 (Precursor) GN=ADAMTSL1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ADAMTS-like 1 [Equus caballus]
ENSG00000178033(FAM26E)	--	0.2440457	40	0.259798571	43	0.248790893	40	0.385886583	64	0.336432948	55	0.344565916	57	0.869566804	0.628018682	normal	0.964380153	0.323585045	normal	0.939165961	0.487167915	normal	0.387844549	0.495240418	normal	--	--	--	--	--	--	--	Calcium homeostasis modulator	Protein FAM26E GN=FAM26E OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM26E [Ursus maritimus]
ENSG00000178035(IMPDH2)	--	109.7620794	3339	85.31499624	2632	91.66904816	2828	115.15805	3554	111.0545254	3346	79.87927096	2452	0.990561304	0.059168933	normal	0.924284286	0.324685594	normal	0.973267075	-0.213991577	normal	0.868989377	0.065679528	normal	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: N-acetylmannosamine metabolic process (GO:0006051);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: nitronate monooxygenase activity (GO:0018580);; Molecular Function: N-acylglucosamine-6-phosphate 2-epimerase activity (GO:0047465);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00088|0|hsa:3615|IMPDH2, IMPD2, IMPDH-II; IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205); K00088 IMP dehydrogenase [EC:1.1.1.205] (A)"	Purine metabolism (ko00230);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	IMP dehydrogenase / GMP reductase domain;; CBS domain;; Nitronate monooxygenase;; FMN-dependent dehydrogenase;; Histidine biosynthesis protein;; Putative N-acetylmannosamine-6-phosphate epimerase	Inosine-5'-monophosphate dehydrogenase 2 {ECO:0000255|HAMAP-Rule:MF_03156} OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: inosine-5'-monophosphate dehydrogenase 2 isoform X2 [Ailuropoda melanoleuca] 
ENSG00000178038(ALS2CL)	--	1.6111659	163	1.772801988	186	1.266262272	150	2.32117789	216	2.197237362	191	1.37328776	146	0.863064378	0.372270446	normal	0.965778086	0.016709395	normal	0.967227556	-0.046807227	normal	0.777925229	0.125628731	normal	[S]	Function unknown	--	--	--	[R]	General function prediction only	MORN repeat;; Vacuolar sorting protein 9 (VPS9) domain	ALS2 C-terminal-like protein GN=ALS2CL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ALS2 C-terminal-like protein isoform X2 [Bubalus bubalis]
ENSG00000178053(MLF1)	--	11.74038721	338	8.869556421	231	9.031899051	274	6.607195745	189	9.402357249	270	4.974303091	134	0.002440842	-0.864137543	normal	0.944895732	0.20241332	normal	0.000221539	-1.031915405	down	0.231098047	-0.529249161	normal	--	--	--	K15622|0|mcf:102138940|MLF1; myeloid leukemia factor 1; K15622 myeloid leukemia factor 1 (A)	Transcriptional misregulation in cancer (ko05202)	[S]	Function unknown	Myelodysplasia-myeloid leukemia factor 1-interacting protein	Myeloid leukemia factor 1 GN=MLF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: myeloid leukemia factor 1 isoform X1 [Tupaia chinensis]
ENSG00000178057(NDUFAF3)	--	20.606039	512	19.5353	526	19.2247	534	17.00738	441	16.79972	481	14.9462	379	0.929072046	-0.245402996	normal	0.95947939	-0.150001285	normal	0.408698302	-0.501239893	normal	0.179626905	-0.294474602	normal	[S]	Function unknown	--	"K09008|6.22038e-133|hsa:25915|NDUFAF3, 2P1, C3orf60, E3-3; NADH dehydrogenase (ubiquinone) complex I, assembly factor 3; K09008 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 (A)"	--	[S]	Function unknown	Protein of unknown function (DUF498/DUF598)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 GN=NDUFAF3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 isoform X2 [Galeopterus variegatus]
ENSG00000178074(C2orf69)	--	9.80915	504	9.45289	486	10.7788	544	7.80799	406	6.30321	324	6.64717	342	0.84476722	-0.341613289	normal	0.134903152	-0.604070128	normal	0.031188232	-0.675511684	normal	0.005873588	-0.538616283	normal	--	--	--	--	--	[R]	General function prediction only	Uncharacterised protein family UPF0565	UPF0565 protein C2orf69 (Precursor) GN=C2orf69 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0565 protein C2orf69 homolog [Equus przewalskii]
ENSG00000178075(GRAMD1C)	--	0.315752736	19	0.291740191	21	0.409753755	23	0.220666104	16	0.310984379	22	0.13081167	6	--	--	--	0.987382267	0.042684417	normal	0.535472749	-1.713382119	normal	0.531212578	-0.540508238	normal	--	--	--	--	--	[S]	Function unknown	GRAM domain	GRAM domain-containing protein 1C GN=GRAMD1C OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: GRAM domain-containing protein 1C [Galeopterus variegatus]
ENSG00000178078(STAP2)	--	0.042011369	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Signal-transducing adaptor protein 2 GN=STAP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: signal-transducing adaptor protein 2 [Galeopterus variegatus]
ENSG00000178093(TSSK6)	--	2.22272	49	1.62553	37	2.12411	49	0.932048	21	1.34339	30	1.4569	33	0.300383266	-1.194375881	normal	0.975774618	-0.309896094	normal	0.935478574	-0.557509932	normal	0.230813583	-0.704025935	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08811|0|hsa:83983|TSSK6, CT72, SSTK, TSSK4; testis-specific serine kinase 6 (EC:2.7.11.1); K08811 testis-specific serine kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	Testis-specific serine/threonine-protein kinase 6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	testis-specific serine kinase 6 [Sus scrofa] 
ENSG00000178096(BOLA1)	--	13.953139	209	13.316145	205	15.65327991	254	9.515318	156	8.089704024	112	9.475186	139	0.765570732	-0.448953703	normal	0.013777281	-0.884584518	normal	0.006823232	-0.870918657	normal	0.006975083	-0.736135513	normal	[T]	Signal transduction mechanisms	--	K05527|3.36128e-92|hsa:51027|BOLA1; bolA family member 1; K05527 BolA protein (A)	--	[T]	Signal transduction mechanisms	BolA-like protein	BolA-like protein 1 GN=BOLA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: bolA-like protein 1 [Loxodonta africana]
ENSG00000178104(PDE4DIP)	--	4.031998188	496	4.261311608	486	4.123506409	528	3.414958282	418	3.836137675	430	4.467823893	493	0.910129558	-0.276734248	normal	0.947311242	-0.197392719	normal	0.966615371	-0.106924717	normal	0.441745224	-0.191803952	normal	--	--	Cellular Component: microtubule organizing center (GO:0005815);; 	K16549|0|mcf:101866504|uncharacterized LOC101866504; K16549 myomegalin (A)	--	--	--	Microtubule associated;; Repeat of unknown function (DUF1220)	Myomegalin GN=PDE4DIP OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: myomegalin isoform X18 [Equus przewalskii]
ENSG00000178105(DDX10)	--	8.142183	637	8.45713	654	8.9312814	684	10.4576511	825	10.5944206	825	8.4973076	666	0.842515829	0.341542938	normal	0.88326137	0.313031202	normal	0.974154586	-0.046661036	normal	0.323753435	0.208119098	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14776|0|hsa:1662|DDX10, HRH-J8; DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 (EC:3.6.4.13); K14776 ATP-dependent RNA helicase DDX10/DBP4 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Domain of unknown function (DUF4217);; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX10 GN=DDX10 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX10 [Ceratotherium simum simum]
ENSG00000178115(GOLGA8Q)	--	0.0205273	1	0.0403106	2	0.0992238	4	0.0611042	3	0.0597899	2	0.0609835	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8N OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: golgin subfamily A member 2-like [Pteropus alecto]
ENSG00000178125(PPP1R42)	--	0.138148783	2	0.0697962	1	0	0	0	0	0.0666178	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17579|0|nle:100590906|PPP1R42; protein phosphatase 1, regulatory subunit 42; K17579 protein phosphatase 1 regulatory subunit 42 (A)"	--	[A]	RNA processing and modification	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich Repeat	Protein phosphatase 1 regulatory subunit 42 GN=PPP1R42 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 42 [Loxodonta africana]
ENSG00000178127(NDUFV2)	--	99.348104	1290	93.43669538	1231	95.32979054	1249	97.972198	1300	92.69111661	1200	109.5604958	1432	0.982345688	-0.019668371	normal	0.9801812	-0.058150556	normal	0.96677382	0.188752982	normal	0.888638208	0.039752379	normal	[C]	Energy production and conversion	--	"K03943|1.66213e-171|hsa:4729|NDUFV2, CI-24k; NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa (EC:1.6.5.3 1.6.99.3); K03943 NADH dehydrogenase (ubiquinone) flavoprotein 2 [EC:1.6.5.3 1.6.99.3] (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Thioredoxin-like [2Fe-2S] ferredoxin	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial (Precursor) GN=NDUFV2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000178149(DALRD3)	--	14.515249	361	12.291282	341	12.856513	363	15.194272	380	14.869002	403	14.9497353	406	0.968275557	0.042989982	normal	0.939091544	0.218688575	normal	0.957467927	0.152617255	normal	0.649305813	0.137996025	normal	--	--	Molecular Function: arginine-tRNA ligase activity (GO:0004814);; Molecular Function: ATP binding (GO:0005524);; Biological Process: arginyl-tRNA aminoacylation (GO:0006420);; 	--	--	--	--	DALR anticodon binding domain	DALR anticodon-binding domain-containing protein 3 GN=DALRD3 OS=Homo sapiens (Human) PE=2 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: DALR anticodon-binding domain-containing protein 3 [Galeopterus variegatus]
ENSG00000178150(ZNF114)	--	1.809754158	103	3.003887	97	1.584942519	83	2.441974138	140	1.978184098	94	4.247180557	205	0.881319343	0.406729129	normal	0.969044675	-0.065709811	normal	1.16E-05	1.280807697	up	0.312122385	0.613015029	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100968796|ZNF114; zinc finger protein 114; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; KRAB box;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 114 GN=ZNF114 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 114 [Ceratotherium simum simum]
ENSG00000178163(ZNF518B)	--	5.54648082	670	4.616696464	556	4.44210511	529	6.2763003	541	4.657741	561	4.66579799	531	0.845804958	-0.338498962	normal	0.97221025	-0.008487688	normal	0.972431766	-0.002839202	normal	0.635877617	-0.125380137	normal	--	--	--	--	--	--	--	C2H2-type zinc-finger domain;; Zinc-finger double domain	Zinc finger protein 518B GN=ZNF518B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 518B [Galeopterus variegatus]
ENSG00000178172(SPINK6)	--	0	0	0	0	0.295090377	1	0.823218	6	1.301192083	6	0.295254017	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Serine protease inhibitor Kazal-type 6 (Precursor) GN=SPINK6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: serine protease inhibitor Kazal-type 6 [Chrysochloris asiatica]
ENSG00000178177(LCORL)	--	3.75735923	350	3.7637313	343	4.3633847	405	3.6887453	355	4.43198002	419	3.72828015	342	0.968698921	-0.010323166	normal	0.917243434	0.266251512	normal	0.926079723	-0.251195023	normal	1	0.002552035	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4553)	Putative uncharacterized protein ENSP00000382790 OS=Homo sapiens (Human) PE=5 SV=3	S	Function unknown	PREDICTED: uncharacterized protein LOC101689974 isoform X2 [Mustela putorius furo]
ENSG00000178184(PARD6G)	--	4.577327435	208	3.0470686	152	3.61311623	184	3.322059067	132	3.506245414	171	3.050130295	127	0.192229393	-0.68050938	normal	0.958321899	0.147117879	normal	0.623911747	-0.537817298	normal	0.299637679	-0.36031275	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06093|0|hsa:84552|PARD6G, PAR-6G, PAR6gamma; par-6 family cell polarity regulator gamma; K06093 partitioning defective protein 6 (A)"	Rap1 signaling pathway (ko04015);; Endocytosis (ko04144);; Hippo signaling pathway (ko04390);; Tight junction (ko04530)	[T]	Signal transduction mechanisms	PB1 domain;; PDZ domain (Also known as DHR or GLGF)	Partitioning defective 6 homolog gamma GN=PARD6G OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: partitioning defective 6 homolog gamma [Ochotona princeps]
ENSG00000178188(SH2B1)	--	15.51948782	980	16.68787474	1083	16.0167666	1015	14.95738322	976	15.29528069	924	13.51863175	962	0.978787586	-0.036675248	normal	0.938859251	-0.250116463	normal	0.976610226	-0.085531452	normal	0.575135028	-0.126272296	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K12459|0|hsa:25970|SH2B1, PSM, SH2B; SH2B adaptor protein 1; K12459 SH2B adaptor protein 1/3 (A)"	Neurotrophin signaling pathway (ko04722)	--	--	Phenylalanine zipper;; PH domain;; SH2 domain	SH2B adapter protein 1 GN=SH2B1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	SH2B adapter protein 1 [Tupaia chinensis]
ENSG00000178199(ZC3H12D)	--	0.00958984	1	0.00946541	1	0.076228709	1	0	0	0.0651569	6	0.098958917	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18668|0|hsa:340152|ZC3H12D, C6orf95, MCPIP4, TFL, dJ281H8.1, p34; zinc finger CCCH-type containing 12D; K18668 ribonuclease ZC3H12 [EC:3.1.-.-] (A)"	--	[S]	Function unknown	Zc3h12a-like Ribonuclease NYN domain	Probable ribonuclease ZC3H12D OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: probable ribonuclease ZC3H12D [Oryctolagus cuniculus]
ENSG00000178201(VN1R1)	--	2.403493202	158	3.161868916	206	3.45083938	189	2.782299085	180	2.535526011	174	3.337482774	225	0.958265285	0.155819814	normal	0.929785734	-0.262880902	normal	0.936999018	0.241474407	normal	0.93492335	0.045751398	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: pheromone receptor activity (GO:0016503);; Biological Process: sensory perception of taste (GO:0050909);; 	"K04614|0|hsa:57191|VN1R1, V1RL1, VNR19I1, ZVNH1, ZVNR1; vomeronasal 1 receptor 1; K04614 vomeronasal1 receptor (A)"	--	--	--	"Vomeronasal organ pheromone receptor family, V1R;; Mammalian taste receptor protein (TAS2R);; 7 transmembrane receptor (rhodopsin family)"	Vomeronasal type-1 receptor 1 GN=VN1R1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	vomeronasal 1 receptor oryCunV1R1612 [Oryctolagus cuniculus]
ENSG00000178202(KDELC2)	--	9.14932014	674	10.146115	742	8.788162535	638	8.17102	600	7.172321	524	5.063462647	374	0.95131857	-0.198139274	normal	0.300912227	-0.522006023	normal	0.002695096	-0.776376904	normal	0.034327844	-0.478133618	normal	--	--	--	--	--	[R]	General function prediction only	Glycosyl transferase family 90;; Filamin/ABP280 repeat	KDEL motif-containing protein 2 (Precursor) GN=KDELC2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: KDEL motif-containing protein 2 [Ceratotherium simum simum]
ENSG00000178209(PLEC)	--	120.3099851	31733	123.698217	33369	132.4786464	36298	147.3757692	39661	125.3691203	31627	124.9528527	33101	0.992215049	0.290892253	normal	0.998212701	-0.098773697	normal	0.997973131	-0.141300531	normal	0.958759529	0.020271534	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoskeleton (GO:0005856);; 	"K10388|0|hsa:5339|PLEC, EBS1, EBSO, HD1, LGMD2Q, PCN, PLEC1, PLEC1b, PLTN; plectin; K10388 plectin (A)"	--	[Z]	Cytoskeleton	Plectin repeat;; Calponin homology (CH) domain;; Plectin/S10 domain;; TfuA-like protein;; CAMSAP CH domain	Plectin GN=PLEC OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: plectin isoform 5 [Ceratotherium simum simum]
ENSG00000178217(SH2D4B)	--	0.014034	1	0	0	0.0273362	1	0.027791213	2	0	0	0.019127215	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SH2 domain-containing protein 4B GN=SH2D4B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SH2 domain-containing protein 4B isoform X5 [Bos taurus]
ENSG00000178222(RNF212)	--	4.573428222	106	3.909220376	85	5.358719858	119	1.069965004	29	2.493850105	60	0.573073531	15	9.32E-07	-1.84605703	down	0.875274521	-0.513006326	normal	5.28E-14	-2.875428049	down	0.000117713	-1.597108111	down	--	--	--	--	--	[DR]	"Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	zinc-RING finger domain	Probable E3 SUMO-protein ligase RNF212 GN=RNF212 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 212 [Ceratotherium simum simum]
ENSG00000178226(PRSS36)	--	0.147031152	7	0.057750916	3	0.099320424	4	0.078471178	4	0.227557549	9	0.111816939	5	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09630|0|hsa:146547|PRSS36; protease, serine, 36; K09630 protease, serine, 36 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Polyserase-2 (Precursor) GN=PRSS36 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polyserase-2 isoform 1 [Ceratotherium simum simum]
ENSG00000178229(ZNF543)	--	1.292396127	89	1.987421	135	1.317036826	91	1.301642869	90	1.205591	81	1.525432308	106	0.972141002	-0.014464293	normal	0.269667583	-0.74746145	normal	0.959802982	0.208619291	normal	0.696556357	-0.206662447	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:125919|ZNF543; zinc finger protein 543; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 543 GN=ZNF543 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 805 [Equus caballus]
ENSG00000178233(TMEM151B)	--	0.1310863	4	0.1156524	3	0.101042	1	0.103441	2	0	0	0.052326	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMEM151 family	Transmembrane protein 151B GN=TMEM151B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 151B [Oryctolagus cuniculus]
ENSG00000178234(GALNT11)	--	20.44026495	917	17.85211514	867	17.99287616	892	18.07164322	801	18.99410615	789	15.89321319	720	0.946493888	-0.225547011	normal	0.964906813	-0.157145781	normal	0.878797076	-0.31673934	normal	0.231053499	-0.233661104	normal	--	--	--	"K00710|0|hsa:63917|GALNT11, GALNACT11; polypeptide N-acetylgalactosaminyltransferase 11 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 11 GN=GALNT11 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 11 [Galeopterus variegatus]
ENSG00000178235(SLITRK1)	--	0.0110149	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	SLIT and NTRK-like protein 1 (Precursor) GN=SLITRK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SLIT and NTRK-like protein 1 [Vicugna pacos]
ENSG00000178252(WDR6)	--	88.21568254	3017	100.438912	3289	67.08751225	3192	50.40726034	2803	53.84719454	3084	59.35684423	3339	0.985431033	-0.136902859	normal	0.987580226	-0.114218553	normal	0.990211558	0.056637762	normal	0.799994436	-0.062564467	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	WD repeat-containing protein 6 GN=WDR6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 6 [Odobenus rosmarus divergens]
ENSG00000178295(GEN1)	--	11.868058	1476	11.3102489	1595	11.4894379	1572	8.092741	1121	7.3123144	1073	10.516932	1356	0.637607981	-0.427226553	normal	0.079968666	-0.592643007	normal	0.959462428	-0.221306027	normal	0.007998792	-0.407859663	normal	[L]	"Replication, recombination and repair"	Molecular Function: nuclease activity (GO:0004518);; Biological Process: DNA repair (GO:0006281);; 	"K15338|0|hsa:348654|GEN1, Gen; GEN1 Holliday junction 5' flap endonuclease; K15338 flap endonuclease GEN [EC:3.1.-.-] (A)"	--	--	--	XPG I-region;; XPG N-terminal domain	Flap endonuclease GEN homolog 1 GN=GEN1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: flap endonuclease GEN homolog 1 [Ceratotherium simum simum]
ENSG00000178297(TMPRSS9)	--	0.01555854	1	0	0	0.02966721	1	0.076561676	5	0.037265542	1	0.077162656	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; 	"K09640|0|hsa:360200|TMPRSS9; transmembrane protease, serine 9; K09640 transmembrane protease, serine 9 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986);; Low-density lipoprotein receptor domain class A	Serase-3 GN=TMPRSS9 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 9 [Trichechus manatus latirostris]
ENSG00000178301(AQP11)	--	2.648026	83	2.429894	78	3.031536	98	2.538786	80	2.948706	96	3.12732	104	0.971966571	-0.082389957	normal	0.95177009	0.273349541	normal	0.969413662	0.076295416	normal	0.894182217	0.092471935	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; 	"K09870|5.40234e-173|hsa:282679|AQP11, AQPX1; aquaporin 11; K09870 aquaporin-11 (A)"	--	--	--	Major intrinsic protein	Aquaporin-11 GN=AQP11 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: aquaporin-11 [Galeopterus variegatus]
ENSG00000178307(TMEM11)	--	17.87606089	701	15.84030691	642	16.9077893	685	19.72423977	795	18.68087	742	17.83642229	709	0.964986855	0.150398482	normal	0.955426014	0.187009297	normal	0.97472585	0.041300571	normal	0.606223558	0.125812082	normal	--	--	Biological Process: mitochondrion organization (GO:0007005);; Cellular Component: integral component of mitochondrial inner membrane (GO:0031305);; 	--	--	--	--	Mitochondrial morphogenesis regulator	"Transmembrane protein 11, mitochondrial GN=TMEM11 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: transmembrane protein 11, mitochondrial isoform X1 [Pteropus alecto]"
ENSG00000178338(ZNF354B)	--	3.782263059	325	3.005006929	289	4.496742001	289	2.033820419	200	3.187676242	271	3.009084496	291	0.035264169	-0.726845377	normal	0.960658368	-0.113589241	normal	0.967720013	0.001649616	normal	0.351624737	-0.265057265	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:117608|ZNF354B, KID2; zinc finger protein 354B; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 354B GN=ZNF354B OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 354B [Leptonychotes weddellii]
ENSG00000178342(KCNG2)	--	0.211141	3	0.19768	3	0.0636588	0	0	0	0.337606	4	0.550326	8	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04901|0|hsa:26251|KCNG2, KCNF2, KV6.2; potassium voltage-gated channel, subfamily G, member 2; K04901 potassium voltage-gated channel subfamily G member 2 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion transport protein;; BTB/POZ domain;; Ion channel	Potassium voltage-gated channel subfamily G member 2 GN=KCNG2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily G member 2 isoform X1 [Sus scrofa] 
ENSG00000178343(SHISA3)	--	0.0363893	1	0	0	0	0	0.0729131	2	0	0	0.0359186	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Wnt and FGF inhibitory regulator	Protein shisa-3 homolog (Precursor) GN=SHISA3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: protein shisa-3 homolog [Galeopterus variegatus]
ENSG00000178358(OR2D3)	--	0.0882265	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:120775|OR2D3, OR11-89; olfactory receptor, family 2, subfamily D, member 3; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 2D3 GN=OR2D3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 2D3-like [Panthera tigris altaica]
ENSG00000178381(ZFAND2A)	--	19.05776129	240	27.039357	352	24.286253	304	25.41107755	340	29.424486	357	22.62649701	291	0.616009999	0.469133734	normal	0.967933083	-0.001073334	normal	0.965647688	-0.070982664	normal	0.72460536	0.119405015	normal	[R]	General function prediction only	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[R]	General function prediction only	AN1-like Zinc finger	AN1-type zinc finger protein 2A GN=ZFAND2A OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: AN1-type zinc finger protein 2A isoform X1 [Galeopterus variegatus] 
ENSG00000178385(PLEKHM3)	--	2.094598906	354	1.933817998	329	1.792850564	278	1.322056706	229	1.360975432	237	1.698177744	276	0.091160379	-0.655665441	normal	0.558902563	-0.491949925	normal	0.967384636	-0.018606475	normal	0.117468711	-0.394090812	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4206);; PH domain	Pleckstrin homology domain-containing family M member 3 GN=PLEKHM3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family M member 3 [Galeopterus variegatus]
ENSG00000178386(ZNF223)	--	2.4609745	119	2.378699	111	3.019667792	117	2.658708938	113	2.79049748	130	2.859585591	159	0.966809567	-0.104091635	normal	0.954686327	0.20395566	normal	0.843398542	0.429447611	normal	0.690662532	0.192146993	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7766|ZNF223; zinc finger protein 223; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 223 GN=ZNF223 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein-like [Galeopterus variegatus]
ENSG00000178395(CCDC185)	--	0	0	0.0201069	1	0.0392239	1	0	0	0.0405036	1	0.0206158	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4659)	Coiled-coil domain-containing protein 185 GN=CCDC185 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C1orf65 homolog [Ceratotherium simum simum]
ENSG00000178397(FAM220A)	--	12.360181	463	12.2377873	463	13.501721	510	13.535136	510	12.297188	459	12.92346	488	0.96582123	0.10831026	normal	0.969717894	-0.033833607	normal	0.969489522	-0.0716902	normal	1	-0.000243122	normal	--	--	--	--	--	--	--	FAM220 family	Protein FAM220A GN=FAM220A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM220A-like [Galeopterus variegatus]
ENSG00000178401(DNAJC22)	--	11.6337312	1002	11.27398159	1101	12.21957994	1087	14.34240456	1302	17.68367626	1463	13.31404006	1157	0.846527373	0.346547405	normal	0.772710429	0.388224762	normal	0.978453565	0.081635382	normal	0.110170041	0.276638724	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	--	--	DnaJ domain;; TM2 domain	DnaJ homolog subfamily C member 22 GN=DNAJC22 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily C member 22 [Galeopterus variegatus]
ENSG00000178409(BEND3)	--	1.88877585	232	1.969339952	239	1.605461787	194	1.750657039	211	2.1795881	266	1.184159535	146	0.954511049	-0.166556838	normal	0.958234858	0.132195923	normal	0.828949292	-0.414641018	normal	0.826776027	-0.116395255	normal	--	--	--	--	--	--	--	BEN domain	BEN domain-containing protein 3 GN=BEND3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: BEN domain-containing protein 3 [Equus przewalskii]
ENSG00000178425(NT5DC1)	--	20.85849	665	20.42629	596	16.71255	638	17.23144	625	18.58143	626	14.70135	552	0.967626327	-0.120044248	normal	0.972195588	0.049301702	normal	0.944268021	-0.216627047	normal	0.725958999	-0.096321117	normal	--	--	--	--	--	[F]	Nucleotide transport and metabolism	5' nucleotidase family	5'-nucleotidase domain-containing protein 1 GN=NT5DC1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: 5'-nucleotidase domain-containing protein 1 isoform X1 [Felis catus]
ENSG00000178445(GLDC)	--	9.467070661	671	7.884721902	537	8.084387121	630	6.857032081	494	7.223989283	545	5.3730891	431	0.483572984	-0.471370504	normal	0.971891397	-9.22E-05	normal	0.203234145	-0.554336703	normal	0.084702959	-0.343692414	normal	[E]	Amino acid transport and metabolism	Molecular Function: glycine dehydrogenase (decarboxylating) activity (GO:0004375);; Biological Process: cellular amino acid metabolic process (GO:0006520);; Biological Process: glycine catabolic process (GO:0006546);; Molecular Function: lyase activity (GO:0016829);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00281|0|hsa:2731|GLDC, GCE, GCSP, HYGN1; glycine dehydrogenase (decarboxylating) (EC:1.4.4.2); K00281 glycine dehydrogenase [EC:1.4.4.2] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Carbon metabolism (ko01200)"	[E]	Amino acid transport and metabolism	Glycine cleavage system P-protein;; Beta-eliminating lyase;; Aminotransferase class-V	"Glycine dehydrogenase (decarboxylating), mitochondrial (Precursor) GN=GLDC OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: glycine dehydrogenase [decarboxylating], mitochondrial [Tupaia chinensis]"
ENSG00000178449(COX14)	--	44.39577543	406	47.292705	446	44.83140257	428	55.948068	525	58.417372	532	66.87027181	620	0.848296836	0.338875123	normal	0.935262464	0.232234214	normal	0.299941863	0.524816751	normal	0.070983517	0.369026158	normal	--	--	--	K18181|2.23497e-35|ptr:100613511|cytochrome c oxidase assembly protein COX14; K18181 cytochrome c oxidase assembly factor 14 (A)	--	--	--	Cytochrome oxidase c assembly	Cytochrome c oxidase assembly protein COX14 GN=COX14 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cytochrome c oxidase assembly protein COX14-like [Tursiops truncatus]
ENSG00000178460(MCMDC2)	--	1.05736892	48	0.19160489	15	0.520568041	34	0.43987235	35	0.54864839	37	0.40075338	29	0.954567801	-0.468859618	normal	0.586154639	1.201754248	normal	0.981304387	-0.22683737	normal	0.985893701	0.03699599	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication initiation (GO:0006270);; 	--	--	[L]	"Replication, recombination and repair"	MCM2/3/5 family	MCM domain-containing protein 2 GN=MCMDC2 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: MCM domain-containing protein 2 [Bubalus bubalis]
ENSG00000178462(TUBAL3)	--	0.745961	21	0.381738	11	0.217866887	5	0.22043822	6	0.120076247	3	0.073751176	2	0.714710548	-1.606940957	normal	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07374|0|pps:100989319|TUBAL3; tubulin, alpha-like 3; K07374 tubulin alpha (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha chain-like 3 GN=TUBAL3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tubulin alpha chain-like 3 [Equus przewalskii]
ENSG00000178498(DTX3)	--	12.4210905	524	13.28669068	576	10.73880321	460	10.97919497	481	14.10182129	553	17.27325525	723	0.959339015	-0.153891005	normal	0.969464813	-0.0800015	normal	0.040642815	0.642371893	normal	0.705932918	0.151273303	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K06058|0|hsa:196403|DTX3, RNF154, deltex3; deltex 3, E3 ubiquitin ligase; K06058 deltex (A)"	Notch signaling pathway (ko04330)	--	--	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	Probable E3 ubiquitin-protein ligase DTX3 GN=DTX3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase DTX3 [Erinaceus europaeus]
ENSG00000178502(KLHL11)	--	2.867950962	324	3.376936006	381	3.062604199	341	2.65529815	302	3.018744255	340	2.3929199	269	0.959728985	-0.13163078	normal	0.949174632	-0.184905367	normal	0.852352212	-0.348711578	normal	0.434462447	-0.220880543	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10449|0|pps:100981519|KLHL11; kelch-like family member 11; K10449 kelch-like protein 11 (A)	--	[R]	General function prediction only	"BTB And C-terminal Kelch;; BTB/POZ domain;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain"	Kelch-like protein 11 (Precursor) GN=KLHL11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: kelch-like protein 11 [Orycteropus afer afer]
ENSG00000178531(CTXN1)	--	27.2172	470	17.468	315	21.3784	393	24.0224	424	26.3137	456	17.4025	307	0.95276841	-0.178812945	normal	0.424970956	0.51020902	normal	0.825412731	-0.362997512	normal	0.989052177	-0.01090895	normal	--	--	--	--	--	--	--	Cortexin of kidney	Cortexin-1 GN=CTXN1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	TPA: cortexin 1 [Bos taurus]
ENSG00000178537(SLC25A20)	--	7.838131015	272	6.732832965	237	8.200068568	280	6.73744047	236	6.197782334	213	6.637041201	228	0.936164072	-0.234230116	normal	0.951774185	-0.174286406	normal	0.90211749	-0.302868354	normal	0.440446209	-0.242002804	normal	--	--	--	"K15109|0|ptr:460354|SLC25A20; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; K15109 solute carrier family 25 (mitochondrial carnitine/acylcarnitine transporter), member 20/29 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial carnitine/acylcarnitine carrier protein GN=SLC25A20 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial carnitine/acylcarnitine carrier protein isoformX4 [Canis lupus familiaris]
ENSG00000178538(CA8)	--	8.64082	402	8.44929	392	8.4038	408	3.76344	183	2.786445	156	3.531768	203	9.68E-07	-1.159438278	down	1.11E-08	-1.342226826	down	4.47E-05	-1.009964688	down	8.89E-09	-1.169966033	down	[P]	Inorganic ion transport and metabolism	--	K01672|0|ptr:464196|CA8; carbonic anhydrase VIII; K01672 carbonic anhydrase [EC:4.2.1.1] (A)	Nitrogen metabolism (ko00910)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase-related protein GN=CA8 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: carbonic anhydrase-related protein [Canis lupus familiaris] 
ENSG00000178567(EPM2AIP1)	--	8.460344097	902	9.094639872	1032	9.096116091	997	8.24768803	926	7.677751897	883	8.911531849	1024	0.978482316	0.00704066	normal	0.939840196	-0.245994016	normal	0.979400675	0.030213642	normal	0.78854852	-0.06995133	normal	--	--	--	--	--	--	--	--	EPM2A-interacting protein 1 GN=EPM2AIP1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: EPM2A-interacting protein 1 [Tupaia chinensis]
ENSG00000178568(ERBB4)	--	0	0	0	0	0	0	0	0	0.009754588	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein tyrosine kinase activity (GO:0004714);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: transmembrane receptor protein tyrosine kinase signaling pathway (GO:0007169);; Cellular Component: membrane (GO:0016020);; 	K05085|0|mcf:102141308|ERBB4; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4; K05085 receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1] (A)	ErbB signaling pathway (ko04012);; Calcium signaling pathway (ko04020);; Endocytosis (ko04144);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Receptor L domain;; Growth factor receptor domain IV;; Protein kinase domain;; Furin-like cysteine rich region	ERBB4 intracellular domain (Precursor) GN=ERBB4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: receptor tyrosine-protein kinase erbB-4 [Oryctolagus cuniculus]
ENSG00000178573(MAF)	--	0.242936754	5	0.370448955	16	0.111807384	10	3.489785	195	5.991861	320	2.840074	220	0	4.883055827	up	0	4.177983486	up	0	4.258421723	up	1.48E-15	4.546449795	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09035|3.064e-177|ptr:454260|MAF; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog; K09035 transcription factor Maf (A)	Transcriptional misregulation in cancer (ko05202);; Inflammatory bowel disease (IBD) (ko05321)	[K]	Transcription	bZIP Maf transcription factor;; Maf N-terminal region	Transcription factor Maf GN=MAF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor Maf isoform 1 [Dasypus novemcinctus]
ENSG00000178585(CTNNBIP1)	--	9.506775959	345	7.655981398	282	8.95956198	311	7.793094667	293	9.298239841	352	7.981059	260	0.919622307	-0.2652444	normal	0.899311025	0.297025513	normal	0.921435194	-0.265281586	normal	0.849930177	-0.073036422	normal	--	--	--	"K04493|6.71279e-53|ptr:749394|CTNNBIP1; catenin, beta interacting protein 1; K04493 Beta-catenin-interacting protein 1 (Inhibitor of beta-catenin and Tcf-4) (A)"	Wnt signaling pathway (ko04310)	--	--	Beta-catenin-interacting protein ICAT	Beta-catenin-interacting protein 1 GN=CTNNBIP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: beta-catenin-interacting protein 1 [Condylura cristata]
ENSG00000178597(PSAPL1)	--	0.0601932	6	0.0981383	10	0.0675481	6	0.0302226	3	0	0	0.0299116	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	K12382|0|hsa:768239|PSAPL1; prosaposin-like 1 (gene/pseudogene); K12382 saposin (A)	Lysosome (ko04142)	[IG]	Lipid transport and metabolism;; Carbohydrate transport and metabolism	"Saposin A-type domain;; Saposin-like type B, region 1;; Saposin-like type B, region 2"	Saposin D-like (Precursor) GN=PSAPL1 OS=Homo sapiens (Human) PE=2 SV=2	GI	Carbohydrate transport and metabolism;; Lipid transport and metabolism	PREDICTED: proactivator polypeptide-like 1 [Galeopterus variegatus]
ENSG00000178605(GTPBP6)	--	23.2843	904	26.6207	1070	25.7485	1045	18.8487	742	21.3713	833	21.2019	832	0.880525204	-0.315143487	normal	0.775247673	-0.38203522	normal	0.855939834	-0.336591808	normal	0.041966434	-0.347579426	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	50S ribosome-binding GTPase	Putative GTP-binding protein 6 GN=GTPBP6 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: putative GTP-binding protein 6 [Leptonychotes weddellii]
ENSG00000178607(ERN1)	--	7.915857	854	12.18193	1234	5.67841	608	4.24224601	459	5.645842	638	10.73673	1268	2.61E-05	-0.924267081	normal	3.81E-06	-0.971453483	normal	1.70E-07	1.05027093	up	0.851622546	-0.208131405	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: ribonuclease activity (GO:0004540);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: mRNA processing (GO:0006397);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08852|0|hsa:2081|ERN1, IRE1, IRE1P, IRE1a, hIRE1p; endoplasmic reticulum to nucleus signaling 1 (EC:2.7.11.1); K08852 serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010)	[T]	Signal transduction mechanisms	Ribonuclease 2-5A;; Protein kinase domain;; Protein tyrosine kinase;; PQQ-like domain;; PQQ enzyme repeat	Endoribonuclease (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase/endoribonuclease IRE1 [Equus caballus]
ENSG00000178662(CSRNP3)	--	0.087285372	16	0.079014576	8	1.302666378	20	0.173982916	33	0.440797153	27	0.409458281	27	0.8780414	0.948966535	normal	0.501665645	1.564565049	normal	0.980718037	0.398642727	normal	0.147913306	0.96273453	normal	--	--	--	K17494|0|mcf:102118461|CSRNP3; cysteine-serine-rich nuclear protein 3; K17494 cysteine/serine-rich nuclear protein (A)	--	--	--	--	Cysteine/serine-rich nuclear protein 3 GN=CSRNP3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: cysteine/serine-rich nuclear protein 3 isoform X1 [Oryctolagus cuniculus] 
ENSG00000178685(PARP10)	--	0.47791578	32	0.815159409	44	0.674697222	38	1.744871851	80	1.553726926	96	1.790355556	113	0.021370162	1.251879046	normal	0.042606271	1.078423478	normal	4.85E-05	1.527051097	up	0.000816463	1.321828563	up	--	--	Molecular Function: NAD+ ADP-ribosyltransferase activity (GO:0003950);; 	"K15261|0|hsa:84875|PARP10, ARTD10; poly (ADP-ribose) polymerase family, member 10 (EC:2.4.2.30); K15261 poly [ADP-ribose] polymerase 10/14/15 [EC:2.4.2.30] (A)"	--	--	--	Poly(ADP-ribose) polymerase catalytic domain	Poly [ADP-ribose] polymerase 10 GN=PARP10 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: poly [ADP-ribose] polymerase 10 [Trichechus manatus latirostris]
ENSG00000178690(DYNAP)	--	0	0	0	0	0	0	0.032307315	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Dynactin-associated protein GN=DYNAP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: dynactin-associated protein, partial [Tupaia chinensis]"
ENSG00000178691(SUZ12)	--	30.78308	2276	31.73715	2355	31.05135	2243	30.65458	2287	29.77049	2208	27.34606	2039	0.987916527	-0.023860387	normal	0.98422491	-0.1143376	normal	0.98102174	-0.145756172	normal	0.675455817	-0.094769503	normal	--	--	--	"K11463|0|hsa:23512|SUZ12, CHET9, JJAZ1; SUZ12 polycomb repressive complex 2 subunit; K11463 polycomb protein SUZ12 (A)"	--	[R]	General function prediction only	VEFS-Box of polycomb protein	Polycomb protein SUZ12 GN=SUZ12 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: polycomb protein SUZ12 [Lipotes vexillifer]
ENSG00000178694(NSUN3)	--	3.45962	239	4.856191	311	4.541293	297	3.83002005	288	3.923127	266	4.522754	300	0.934824853	0.236837433	normal	0.929343869	-0.245621907	normal	0.967840813	0.006176834	normal	0.987937896	-0.009144692	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	NOL1/NOP2/sun family;; Methyltransferase domain	Putative methyltransferase NSUN3 GN=NSUN3 OS=Homo sapiens (Human) PE=2 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: putative methyltransferase NSUN3 [Bubalus bubalis]
ENSG00000178695(KCTD12)	--	6.67582	612	4.36057	401	6.62169	604	3.19678	296	3.18185	292	2.57117	237	1.00E-06	-1.074796618	down	0.560139685	-0.47694303	normal	1.51E-10	-1.352347443	down	0.001084667	-0.992241807	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD12 GN=KCTD12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD12 [Camelus bactrianus]
ENSG00000178700(DHFR2)	--	6.507536786	482	4.594375485	343	6.230996007	394	4.291243736	300	4.078159964	283	4.40331144	313	0.01864583	-0.711996917	normal	0.899217998	-0.297387064	normal	0.857070175	-0.338861789	normal	0.036130255	-0.465227904	normal	[H]	Coenzyme transport and metabolism	Molecular Function: dihydrofolate reductase activity (GO:0004146);; Biological Process: glycine biosynthetic process (GO:0006545);; Biological Process: nucleotide biosynthetic process (GO:0009165);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00287|8.62635e-137|hsa:200895|DHFRL1, DHFRP4; dihydrofolate reductase-like 1 (EC:1.5.1.3); K00287 dihydrofolate reductase [EC:1.5.1.3] (A)"	One carbon pool by folate (ko00670);; Folate biosynthesis (ko00790)	[H]	Coenzyme transport and metabolism	Dihydrofolate reductase	"Dihydrofolate reductase, mitochondrial GN=DHFRL1 OS=Homo sapiens (Human) PE=1 SV=1"	H	Coenzyme transport and metabolism	PREDICTED: dihydrofolate reductase [Tupaia chinensis] 
ENSG00000178718(RPP25)	--	17.0146	957	15.0855	866	14.2862	828	13.8091	781	15.2427	858	15.3385	872	0.871546439	-0.323452616	normal	0.976848395	-0.034754961	normal	0.975956627	0.066287939	normal	0.687403217	-0.099255804	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K14525|7.2775e-98|nle:100589509|RPP25; ribonuclease P/MRP 25kDa subunit; K14525 ribonucleases P/MRP protein subunit RPP25 [EC:3.1.26.5] (A)	Ribosome biogenesis in eukaryotes (ko03008);; RNA transport (ko03013)	[S]	Function unknown	Alba	Ribonuclease P protein subunit p25 GN=RPP25 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ribonuclease P protein subunit p25 [Balaenoptera acutorostrata scammoni]
ENSG00000178719(GRINA)	--	146.52482	4302	143.85845	4231	147.726164	4390	150.32373	4481	148.34746	4402	159.17187	4759	0.992605878	0.02797115	normal	0.992176245	0.035721384	normal	0.990998014	0.108110295	normal	0.826877892	0.057147275	normal	--	--	--	"K06890|8.07116e-146|pon:100445216|GRINA; glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); K06890 (A)"	--	[T]	Signal transduction mechanisms	Inhibitor of apoptosis-promoting Bax1	Protein lifeguard 1 GN=GRINA OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein lifeguard 1 [Galeopterus variegatus]
ENSG00000178726(THBD)	--	6.3652	400	5.41081	342	6.02318	383	31.987	2017	44.6201	2815	23.0118	1462	0	2.298945151	up	0	3.014102504	up	0	1.920062396	up	7.64E-06	2.462404069	up	--	--	Molecular Function: transmembrane signaling receptor activity (GO:0004888);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K03907|0|hsa:7056|THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM; thrombomodulin; K03907 thrombomodulin (A)"	Complement and coagulation cascades (ko04610)	--	--	"Coagulation Factor Xa inhibitory site;; Thrombomodulin like fifth domain, EGF-like;; Complement Clr-like EGF-like;; Calcium-binding EGF domain;; EGF-like domain"	Thrombomodulin (Precursor) GN=THBD OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	hypothetical protein PANDA_015023 [Ailuropoda melanoleuca]
ENSG00000178732(GP5)	--	0	0	0	0	0	0	0	0	0.0568401	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06260|0|hsa:2814|GP5, CD42d, GPV; glycoprotein V (platelet); K06260 platelet glycoprotein V (A)"	ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Hematopoietic cell lineage (ko04640)	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat	Platelet glycoprotein V (Precursor) GN=GP5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: glycoprotein V (platelet) [Ceratotherium simum simum]
ENSG00000178741(COX5A)	--	184.67876	2100	202.88308	2223	184.014259	2192	222.39529	2517	204.09182	2185	228.73687	2497	0.966331284	0.23032954	normal	0.986893908	-0.046269477	normal	0.977834824	0.17954045	normal	0.559207148	0.122767764	normal	--	--	Molecular Function: cytochrome-c oxidase activity (GO:0004129);; Cellular Component: mitochondrial inner membrane (GO:0005743);; 	"K02264|4.31775e-77|hsa:9377|COX5A, COX, COX-VA, VA; cytochrome c oxidase subunit Va (EC:1.9.3.1); K02264 cytochrome c oxidase subunit 5a (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome c oxidase subunit Va	"Cytochrome c oxidase subunit 5A, mitochondrial (Precursor) GN=COX5A OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: cytochrome c oxidase subunit 5A, mitochondrial-like [Lipotes vexillifer]"
ENSG00000178750(STX19)	--	0.0982506	2	0.0492157	1	0.0488811	0	0	0	0	0	0.0967932	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	K08487|0|hsa:415117|STX19; syntaxin 19; K08487 syntaxin 11 (A)	SNARE interactions in vesicular transport (ko04130)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SNARE domain;; Syntaxin	Syntaxin-19 GN=STX19 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: syntaxin-19 isoform X1 [Tupaia chinensis] 
ENSG00000178752(ERFE)	--	4.91921762	225	4.507938799	191	4.373751824	161	1.366292267	63	2.07797932	89	4.052087443	138	1.20E-11	-1.841917336	down	0.000479447	-1.109928359	down	0.947279458	-0.228364535	normal	0.004734443	-1.011793543	down	--	--	--	--	--	--	--	--	Erythroferrone (Precursor) GN=FAM132B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM132B [Odobenus rosmarus divergens]
ENSG00000178761(FAM219B)	--	20.64532201	863	14.348728	725	22.273607	865	15.6239451	728	17.77082	857	20.09951404	904	0.916905003	-0.27571912	normal	0.947353837	0.219466198	normal	0.976993053	0.055236728	normal	1	0.000697877	normal	--	--	--	--	--	--	--	Protein family FAM219A	Protein FAM219B GN=FAM219B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM219B isoform 2 [Dasypus novemcinctus]
ENSG00000178764(ZHX2)	--	1.7764184	171	1.406621561	137	1.870476298	164	3.338659428	248	2.73903	267	3.305814	297	0.613320526	0.50174925	normal	0.00212109	0.933724881	normal	0.006416972	0.842619428	normal	0.002188161	0.762210351	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	"Homeobox domain;; Homeobox KN domain;; Homeodomain leucine-zipper encoding, Homez;; C2H2-type zinc-finger domain"	Zinc fingers and homeoboxes protein 2 GN=ZHX2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc fingers and homeoboxes protein 2 [Ceratotherium simum simum]
ENSG00000178773(CPNE7)	--	25.74837	1080	30.16183	1292	24.52034	1082	30.34209	1209	25.050867	1031	30.20902	1267	0.974000779	0.131773431	normal	0.851984863	-0.346533149	normal	0.955491096	0.219141266	normal	1	0.000647959	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-7 GN=CPNE7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	"Copine-7, partial [Bos mutus]"
ENSG00000178776(C5orf46)	--	0	0	0.177913	1	0	0	0.883535	5	0.511348	2	0.34859	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4576)	Uncharacterized protein C5orf46 (Precursor) GN=C5orf46 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C5orf46 isoform X1 [Canis lupus familiaris]
ENSG00000178795(GDPD4)	--	0.04709821	2	0.0230437	1	0	0	0.0228419	1	0.02287326	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Biological Process: lipid metabolic process (GO:0006629);; Molecular Function: phosphoric diester hydrolase activity (GO:0008081);; 	--	--	[C]	Energy production and conversion	Glycerophosphoryl diester phosphodiesterase family	Glycerophosphodiester phosphodiesterase domain-containing protein 4 GN=GDPD4 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: glycerophosphodiester phosphodiesterase domain-containing protein 4 [Equus caballus]
ENSG00000178796(RIIAD1)	--	0	0	0	0	0	0	0	0	0.315441006	0	0.309931038	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Regulatory subunit of type II PKA R-subunit	RIIa domain-containing protein 1 GN=RIIAD1 OS=Homo sapiens (Human) PE=4 SV=1	T	Signal transduction mechanisms	PREDICTED: RIIa domain-containing protein 1 [Condylura cristata]
ENSG00000178802(MPI)	--	29.15152929	868	24.23100113	729	27.75227978	772	28.40915778	800	29.95821206	826	33.19057816	933	0.966965997	-0.148253846	normal	0.963673228	0.158487392	normal	0.926472261	0.264512796	normal	0.724578488	0.090546985	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: mannose-6-phosphate isomerase activity (GO:0004476);; Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: zinc ion binding (GO:0008270);; 	K01809|0|ggo:101133018|MPI; mannose-6-phosphate isomerase isoform 1; K01809 mannose-6-phosphate isomerase [EC:5.3.1.8] (A)	Fructose and mannose metabolism (ko00051);; Amino sugar and nucleotide sugar metabolism (ko00520)	[G]	Carbohydrate transport and metabolism	Phosphomannose isomerase type I	Mannose-6-phosphate isomerase GN=MPI OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: mannose-6-phosphate isomerase isoform X1 [Equus caballus]
ENSG00000178809(TRIM73)	--	2.784850695	117	3.500823614	136	3.3222161	140	2.424192207	94	2.496453962	112	3.113258846	126	0.927557849	-0.341592025	normal	0.932159715	-0.297878072	normal	0.960574435	-0.158489021	normal	0.55303736	-0.263484403	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12024|0|hsa:375593|TRIM73, TRIM50B; tripartite motif containing 73; K12024 tripartite motif-containing protein 50/73/74 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; RING-type zinc-finger;; Ring finger domain"	Tripartite motif-containing protein 73 GN=TRIM73 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM50 [Tupaia chinensis] 
ENSG00000178814(OPLAH)	--	5.968618012	457	5.060022932	397	4.861602274	391	2.479444449	188	3.26096344	246	3.777679632	291	5.77E-09	-1.305216613	down	0.034086168	-0.708444502	normal	0.687198387	-0.432494624	normal	8.45E-05	-0.80008723	normal	[EQ]	"Amino acid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01469|0|hsa:26873|OPLAH, 5-Opase, OPLA, OPLAHD; 5-oxoprolinase (ATP-hydrolysing) (EC:3.5.2.9); K01469 5-oxoprolinase (ATP-hydrolysing) [EC:3.5.2.9] (A)"	Glutathione metabolism (ko00480)	[E]	Amino acid transport and metabolism	Hydantoinase B/oxoprolinase;; Hydantoinase/oxoprolinase;; Hydantoinase/oxoprolinase N-terminal region	5-oxoprolinase GN=OPLAH OS=Homo sapiens (Human) PE=1 SV=3	E	Amino acid transport and metabolism	PREDICTED: 5-oxoprolinase [Ceratotherium simum simum]
ENSG00000178821(TMEM52)	--	2.251732477	15	1.59934246	6	0.934308505	16	0.262529199	2	0.3726347	4	0.52508242	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane 52	Transmembrane protein 52 (Precursor) GN=TMEM52 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: transmembrane protein 52, partial [Galeopterus variegatus]"
ENSG00000178826(TMEM139)	--	0.645515457	22	0.469767145	17	0.593471866	23	1.376020203	49	1.955324326	68	1.294128436	37	0.510745308	1.073069645	normal	0.000154539	1.888466618	up	0.944970887	0.643940804	normal	0.012018776	1.291287593	normal	--	--	--	--	--	--	--	--	Transmembrane protein 139 (Precursor) GN=TMEM139 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 139 [Galeopterus variegatus]
ENSG00000178852(EFCAB13)	--	2.714388364	221	4.825614766	222	3.103450276	240	2.708113747	147	1.76643727	116	2.408477191	173	0.328355321	-0.613790932	normal	0.003428247	-0.94875872	normal	0.679745361	-0.476997525	normal	0.01448805	-0.668201608	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	--	EF-hand calcium-binding domain-containing protein 13 GN=EFCAB13 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: EF-hand calcium-binding domain-containing protein 13 [Ursus maritimus]
ENSG00000178860(MSC)	--	5.92389	199	7.85989	272	3.98256	139	17.2149	586	22.2958	756	24.1892	829	6.28E-13	1.520139893	up	1.70E-12	1.448317699	up	0	2.555065934	up	1.06E-09	1.810428603	up	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09072|3.00642e-106|pps:100973508|MSC; musculin; K09072 musculin (activated B-cell factor-1) (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Musculin GN=MSC OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: musculin [Tupaia chinensis]
ENSG00000178878(APOLD1)	--	0.420006892	31	0.176733459	13	0.226282181	16	0.336120449	25	0.433091054	32	0.362976073	27	0.980606029	-0.32329298	normal	0.722695303	1.187588695	normal	0.962383661	0.69550269	normal	0.563509026	0.46421918	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	Apolipoprotein L	Apolipoprotein L domain-containing protein 1 GN=APOLD1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: apolipoprotein L domain-containing protein 1 [Pteropus alecto]
ENSG00000178882(RFLNA)	--	36.93409227	2802	41.50158391	3174	40.79157207	2923	39.602988	3025	37.763635	2806	47.344687	3623	0.988651843	0.079603909	normal	0.978167616	-0.199112701	normal	0.943950305	0.301303261	normal	0.800153572	0.066529459	normal	--	--	Molecular Function: filamin binding (GO:0031005);; Biological Process: regulation of chondrocyte development (GO:0061181);; Biological Process: actin filament bundle organization (GO:0061572);; 	--	--	--	--	FAM101 family	Filamin-interacting protein FAM101A {ECO:0000305} GN=FAM101A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM101A isoform X1 [Sus scrofa] 
ENSG00000178896(EXOSC4)	--	35.9846438	494	34.90135659	502	35.54549919	515	40.15641538	566	40.70877284	552	30.60065634	426	0.957632767	0.164979129	normal	0.965212532	0.115223246	normal	0.907408684	-0.281101422	normal	0.984925516	0.009264372	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K11600|2.94321e-119|cfr:102504123|EXOSC4; exosome component 4; K11600 exosome complex component RRP41 (A)	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	"3' exoribonuclease family, domain 1;; 3' exoribonuclease family, domain 2"	Exosome complex component RRP41 GN=EXOSC4 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: LOW QUALITY PROTEIN: exosome component 4 [Camelus ferus]
ENSG00000178904(DPY19L3)	--	9.670983317	898	8.03730411	743	9.69317406	881	9.56162713	898	9.271095153	869	10.66528078	984	0.977931475	-0.030779602	normal	0.952956801	0.204182816	normal	0.968285203	0.150979517	normal	0.667417991	0.104618256	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Q-cell neuroblast polarisation	Probable C-mannosyltransferase DPY19L3 GN=DPY19L3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein dpy-19 homolog 3 [Odobenus rosmarus divergens]
ENSG00000178913(TAF7)	--	42.16530055	1842	39.47120014	1735	41.43940082	1801	48.610301	2142	47.97520059	2090	41.75240037	1820	0.974010679	0.186708639	normal	0.956533192	0.246944372	normal	0.985943181	0.006843111	normal	0.456605666	0.148721775	normal	[K]	Transcription	Cellular Component: transcription factor TFIID complex (GO:0005669);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	"K03132|0|ptr:471669|TAF7; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa; K03132 transcription initiation factor TFIID subunit 7 (A)"	Basal transcription factors (ko03022)	[K]	Transcription	TAFII55 protein conserved region	Transcription initiation factor TFIID subunit 7 GN=TAF7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 7 [Ailuropoda melanoleuca]
ENSG00000178917(ZNF852)	--	1.190528846	62	1.756136	78	1.713137326	86	0.991110915	47	0.993608384	46	1.204680596	60	0.947556284	-0.418487194	normal	0.612342144	-0.76375896	normal	0.875262536	-0.516728843	normal	0.230154175	-0.582934637	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Transposase zinc-ribbon domain;; Zinc ribbon domain"	Zinc finger protein 852 GN=ZNF852 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: zinc finger protein with KRAB and SCAN domains 7-like [Physeter catodon]
ENSG00000178919(FOXE1)	--	6.94436	531	5.82287	444	4.973341	433	5.44186	432	5.60621	449	4.71648	375	0.862196106	-0.327460116	normal	0.969901256	-0.005252998	normal	0.941523017	-0.214960388	normal	0.47637683	-0.186526291	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09398|7.14318e-119|hsa:2304|FOXE1, FKHL15, FOXE2, HFKH4, HFKL5, TITF2, TTF-2, TTF2; forkhead box E1; K09398 forkhead box protein E (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein E1 GN=FOXE1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: forkhead box protein E1 [Odobenus rosmarus divergens]
ENSG00000178921(PFAS)	--	29.6344289	2727	33.81852125	3130	34.62697527	3207	27.73159574	2578	23.01220126	2310	24.48373712	2291	0.986252306	-0.111829884	normal	0.592294227	-0.459436883	normal	0.409026066	-0.493261795	normal	0.021898915	-0.357804965	normal	[F]	Nucleotide transport and metabolism	--	"K01952|0|hsa:5198|PFAS, FGAMS, FGAR-AT, FGARAT, PURL; phosphoribosylformylglycinamidine synthase (EC:6.3.5.3); K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] (A)"	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	"CobB/CobQ-like glutamine amidotransferase domain;; AIR synthase related protein, C-terminal domain;; AIR synthase related protein, N-terminal domain"	Phosphoribosylformylglycinamidine synthase GN=PFAS OS=Homo sapiens (Human) PE=1 SV=4	F	Nucleotide transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: phosphoribosylformylglycinamidine synthase [Equus caballus]
ENSG00000178922(HYI)	--	1.603987	25	1.480068	26	0.703659	13	9.79993	178	11.28824085	209	6.740731	129	0	2.728420606	up	0	2.914995718	up	2.22E-16	3.161027369	up	1.58E-12	2.988274586	up	[G]	Carbohydrate transport and metabolism	--	"K01816|3.75809e-172|hsa:81888|HYI, HT036; hydroxypyruvate isomerase (putative) (EC:5.3.1.22); K01816 hydroxypyruvate isomerase [EC:5.3.1.22] (A)"	Glyoxylate and dicarboxylate metabolism (ko00630)	[G]	Carbohydrate transport and metabolism	Xylose isomerase-like TIM barrel	Putative hydroxypyruvate isomerase GN=HYI OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	hydroxypyruvate isomerase (putative) [Panthera tigris altaica] 
ENSG00000178927(C17orf62)	--	41.58069801	1217	37.665783	1124	44.352963	1433	35.67811572	1192	38.623147	1321	41.29611	1238	0.980380364	-0.060699761	normal	0.958792637	0.211299406	normal	0.958241092	-0.219069766	normal	0.916032746	-0.029460133	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4564)	Uncharacterized protein C17orf62 GN=C17orf62 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C17orf62 homolog isoform X3 [Pantholops hodgsonii]
ENSG00000178935(ZNF552)	--	3.17401	141	2.65765	119	4.30919101	190	3.136117693	140	2.839611	124	3.92529	141	0.96779241	-0.040656001	normal	0.967495105	0.037485317	normal	0.807113522	-0.434565354	normal	0.707684786	-0.172479038	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:79818|ZNF552; zinc finger protein 552; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 552 GN=ZNF552 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 154-like [Galeopterus variegatus] 
ENSG00000178947(SMIM10L2A)	--	1.34193	147	0.625642	70	0.879427	97	0.489301	53	0.737803	79	0.69395	76	6.21E-06	-1.475762357	down	0.96866428	0.150019047	normal	0.935036579	-0.354025567	normal	0.320422207	-0.614290556	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4560)	Small integral membrane protein 10 GN=SMIM10 OS=Homo sapiens (Human) PE=4 SV=4	S	Function unknown	PREDICTED: uncharacterized protein LOC105082431 [Camelus bactrianus]
ENSG00000178950(GAK)	--	18.67474131	1165	18.15101975	1089	16.12212208	1185	18.74187989	1285	23.40646904	1517	18.44377536	1375	0.977245703	0.110467393	normal	0.543976771	0.456251524	normal	0.961427992	0.206008843	normal	0.137523278	0.259662254	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08855|0|pps:100981497|GAK; cyclin G associated kinase; K08855 cyclin G-associated kinase [EC:2.7.11.1] (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; C2 domain of PTEN tumour-suppressor protein;; DnaJ domain;; Kinase-like;; CXCXC repeat	Cyclin-G-associated kinase GN=GAK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cyclin-G-associated kinase isoform X2 [Tupaia chinensis]
ENSG00000178951(ZBTB7A)	--	18.747187	1555	19.555515	1736	15.5122158	1334	17.521787	1446	17.979581	1503	19.21371	1638	0.977400013	-0.135540366	normal	0.959130262	-0.229133756	normal	0.925697919	0.287590541	normal	0.9074175	-0.033102268	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10494|0|ptr:468671|ZBTB7A; zinc finger and BTB domain containing 7A; K10494 zinc finger and BTB domain-containing protein 7 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 7A GN=ZBTB7A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 7A isoform X2 [Sus scrofa]
ENSG00000178952(TUFM)	--	116.6390037	4750	113.0420044	4706	116.3810047	4854	127.3370051	5242	123.176582	4984	121.651896	4975	0.991500211	0.111323292	normal	0.992481443	0.06135703	normal	0.993215702	0.027222597	normal	0.794776162	0.065833957	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K02358|0|ptr:454018|TUFM; Tu translation elongation factor, mitochondrial; K02358 elongation factor Tu (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2	"Elongation factor Tu, mitochondrial (Precursor) GN=TUFM OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: elongation factor Tu, mitochondrial [Vicugna pacos] "
ENSG00000178966(RMI1)	--	10.81820505	505	10.74019146	506	11.13907888	551	9.7844	469	7.166257802	346	8.748093604	435	0.961955597	-0.137094762	normal	0.213903111	-0.567726773	normal	0.834183889	-0.348250016	normal	0.107006813	-0.342870926	normal	--	--	Molecular Function: nucleotide binding (GO:0000166);; 	"K10990|0|hsa:80010|RMI1, BLAP75, C9orf76, FAAP75; RecQ mediated genome instability 1; K10990 RecQ-mediated genome instability protein 1 (A)"	Fanconi anemia pathway (ko03460)	[S]	Function unknown	Domain of unknown function (DUF1767)	RecQ-mediated genome instability protein 1 GN=RMI1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: recQ-mediated genome instability protein 1 [Odobenus rosmarus divergens]
ENSG00000178971(CTC1)	--	11.5840032	885	6.9660488	703	10.53496124	967	7.9483462	674	5.427979	609	10.40431927	824	0.644268304	-0.422916803	normal	0.940767688	-0.22798156	normal	0.941754895	-0.238758037	normal	0.283310357	-0.298355845	normal	--	--	Molecular Function: single-stranded DNA binding (GO:0003697);; 	--	--	--	--	"CST, telomere maintenance, complex subunit CTC1"	CST complex subunit CTC1 GN=CTC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: CST complex subunit CTC1 isoform X1 [Equus przewalskii]
ENSG00000178974(FBXO34)	--	9.9820554	657	9.923408389	660	9.279478875	609	9.889006042	651	9.396544869	615	9.88108	633	0.973794677	-0.043964802	normal	0.966555874	-0.123014093	normal	0.973171066	0.047356478	normal	0.897981465	-0.041799445	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10311|0|hsa:55030|FBXO34, Fbx34; F-box protein 34; K10311 F-box protein 34 (A)"	--	--	--	--	F-box only protein 34 GN=FBXO34 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: F-box only protein 34 [Galeopterus variegatus]
ENSG00000178980(SELENOW)	--	74.8077527	889	49.25880426	589	70.22889901	835	69.422957	833	75.36094927	892	36.327396	431	0.970907358	-0.124476881	normal	0.130534843	0.576139498	normal	1.03E-05	-0.959915062	normal	0.864213737	-0.123818046	normal	--	--	--	--	--	--	--	Rdx family	Selenoprotein W GN=SEPW1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: selenoprotein W [Condylura cristata]
ENSG00000178982(EIF3K)	--	281.5685931	3796	247.5860735	3266	277.3258119	3739	270.6233933	3661	264.7983074	3500	241.0445588	3269	0.990481351	-0.083040254	normal	0.989622109	0.078368516	normal	0.980097422	-0.202007084	normal	0.768651092	-0.071815552	normal	--	--	--	"K15028|7.88865e-163|pps:100982948|EIF3K; eukaryotic translation initiation factor 3, subunit K; K15028 translation initiation factor 3 subunit K (A)"	--	[S]	Function unknown	"COP9 signalosome, subunit CSN8;; SAC3/GANP/Nin1/mts3/eIF-3 p25 family"	Eukaryotic translation initiation factor 3 subunit K {ECO:0000255|HAMAP-Rule:MF_03010} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	eukaryotic translation initiation factor 3 subunit K [Bos taurus] 
ENSG00000178988(MRFAP1L1)	--	25.76091	674	24.26567	653	23.78651	631	26.52558	709	26.41889	685	24.97517	650	0.974501646	0.042111176	normal	0.973342367	0.04748706	normal	0.97397957	0.034426975	normal	0.898477272	0.040486904	normal	--	--	--	--	--	--	--	MORF4 family-associated protein1	MORF4 family-associated protein 1-like 1 GN=MRFAP1L1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MORF4 family-associated protein 1-like 1 isoform 1 [Dasypus novemcinctus]
ENSG00000178996(SNX18)	--	10.96633449	790	8.876711899	664	10.00123392	686	6.49453095	447	8.364645154	559	7.564973512	556	0.000253067	-0.85018005	normal	0.917851948	-0.269092611	normal	0.881903388	-0.310652973	normal	0.007257928	-0.474772236	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17923|0|nle:100592166|SNX18; sorting nexin 18; K17923 sorting nexin-9/18/33 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	WASP-binding domain of Sorting nexin protein;; PX domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Sorting nexin-18 GN=SNX18 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-18 [Sus scrofa]
ENSG00000178997(EXD1)	--	0.533165764	12	0.080728004	4	0.045705421	1	0.06040609	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	"K18740|0|hsa:161829|EXD1, EXDL1; exonuclease 3'-5' domain containing 1; K18740 exonuclease 3'-5' domain-containing protein 1 (A)"	--	[L]	"Replication, recombination and repair"	3'-5' exonuclease	Exonuclease 3'-5' domain-containing protein 1 GN=EXD1 OS=Homo sapiens (Human) PE=2 SV=4	L	"Replication, recombination and repair"	PREDICTED: exonuclease 3'-5' domain-containing protein 1 [Galeopterus variegatus]
ENSG00000178999(AURKB)	--	45.07717167	974	40.73175249	904	52.22587806	1144	51.88056115	1147	49.37733	1062	45.38767012	985	0.957962406	0.204741591	normal	0.954606043	0.210637146	normal	0.951711349	-0.223863622	normal	0.826877892	0.058588042	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K11479|0|pon:100448258|AURKB; aurora kinase B; K11479 aurora kinase B [EC:2.7.11.1] (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase	Aurora kinase B GN=AURKB OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: aurora kinase B [Galeopterus variegatus]
ENSG00000179010(MRFAP1)	--	160.7928424	3929	152.3888581	3896	150.1796196	3873	191.8651776	4905	202.4374609	4985	171.975865	4088	0.960118757	0.289157337	normal	0.933624905	0.334058382	normal	0.991294669	0.069625788	normal	0.185256829	0.235211458	normal	--	--	--	--	--	--	--	MORF4 family-associated protein1	MORF4 family-associated protein 1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: MORF4 family-associated protein 1-like [Dasypus novemcinctus]
ENSG00000179021(C3orf38)	--	10.515192	424	11.130124	443	10.77548006	410	12.007	496	11.754	483	11.337434	463	0.948652618	0.194790498	normal	0.96522207	0.102953281	normal	0.95560504	0.16651854	normal	0.572246299	0.153813739	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4518)	Uncharacterized protein C3orf38 GN=C3orf38 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PANDA_016599 [Ailuropoda melanoleuca]
ENSG00000179023(KLHDC7A)	--	0.525305	58	1.45249	164	0.731992	83	2.22122	246	1.93783	214	5.69881	637	4.62E-14	2.025456633	up	0.873452571	0.359578301	normal	0	2.909273911	up	0.153688334	1.827740817	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain"	Kelch domain-containing protein 7A GN=KLHDC7A OS=Homo sapiens (Human) PE=2 SV=5	R	General function prediction only	PREDICTED: kelch domain-containing protein 7A isoform X2 [Tupaia chinensis]
ENSG00000179029(TMEM107)	--	14.064774	252	13.09728149	225	11.30827439	236	14.8039623	256	13.88146557	223	8.132576202	146	0.967163276	-0.008063412	normal	0.965415227	-0.034077779	normal	0.125690303	-0.695389559	normal	0.5643595	-0.212787042	normal	--	--	--	--	--	--	--	Transmembrane protein	Transmembrane protein 107 GN=TMEM107 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 107 isoform 1 [Ceratotherium simum simum]
ENSG00000179044(EXOC3L1)	--	0.099514435	4	0.024189989	1	0.095003123	3	0.200550385	8	0.04921068	1	0.050097499	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: exocytosis (GO:0006887);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec6	Exocyst complex component 3-like protein GN=EXOC3L1 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 3-like protein isoform 2 [Ceratotherium simum simum]
ENSG00000179046(TRIML2)	--	8.833709217	398	15.87966773	778	10.59442877	520	17.6861434	840	18.11190023	908	26.64814718	1353	8.08E-07	1.043953743	up	0.954696378	0.201133403	normal	4.49E-13	1.368725538	up	0.079751089	0.850481459	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	K12039|0|pps:100990538|TRIML2; tripartite motif family-like 2; K12039 tripartite motif family-like protein 2 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPRY domain;; SPRY-associated domain;; B-box zinc finger	Probable E3 ubiquitin-protein ligase TRIML2 GN=TRIML2 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase TRIML2 [Ceratotherium simum simum]
ENSG00000179051(RCC2)	--	32.536668	2334	35.19584	2532	33.538297	2429	39.09576	2758	42.78349	3019	36.30199	2597	0.97350566	0.209858439	normal	0.969751699	0.23223963	normal	0.986988624	0.088139003	normal	0.347745674	0.177688984	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	--	--	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat	Protein RCC2 GN=RCC2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein RCC2 [Camelus dromedarius]
ENSG00000179057(IGSF22)	--	0.00935792	1	0.00916865	1	0.00904778	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Alphaherpesvirus glycoprotein I;; Alphaherpesvirus glycoprotein E	Immunoglobulin superfamily member 22 GN=IGSF22 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 22 [Tupaia chinensis]
ENSG00000179058(C9orf50)	--	0	0	0	0	0.0348266	0	0.0366488	1	0	0	0.108957	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf50 GN=C9orf50 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf50 homolog [Camelus bactrianus]
ENSG00000179071(CCDC89)	--	0.0333059	1	0	0	0	0	0	0	0.0324772	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 89 GN=CCDC89 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 89 [Ceratotherium simum simum]
ENSG00000179083(FAM133A)	--	3.365704804	180	2.507539693	134	2.636157583	136	1.399391348	76	1.882915933	101	1.142194696	61	4.51E-05	-1.257708683	down	0.868656349	-0.42377578	normal	0.002293892	-1.145494383	down	0.003691226	-0.94070805	normal	--	--	--	--	--	--	--	--	Protein FAM133A GN=FAM133A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC101390261 [Ceratotherium simum simum]
ENSG00000179085(DPM3)	--	96.69013	286	94.146614	301	112.25902	353	94.54144	308	101.86101	299	97.926666	302	0.965241471	0.075691074	normal	0.966450899	-0.030888851	normal	0.934970615	-0.232333808	normal	0.858519474	-0.069305568	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; 	"K09659|7.52847e-62|hsa:54344|DPM3, CDG1O; dolichyl-phosphate mannosyltransferase polypeptide 3 (EC:2.4.1.83); K09659 dolichyl-phosphate mannosyltransferase polypeptide 3 (A)"	N-Glycan biosynthesis (ko00510)	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Dolichol-phosphate mannosyltransferase subunit 3 (DPM3)	Dolichol-phosphate mannosyltransferase subunit 3 GN=DPM3 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: dolichol-phosphate mannosyltransferase subunit 3 [Odobenus rosmarus divergens] 
ENSG00000179091(CYC1)	--	139.077	2869	130.089	2736	134.083	2842	137.257	2832	137.137	2804	132.702	2751	0.989342761	-0.049532267	normal	0.989291969	0.013983926	normal	0.98905008	-0.055211994	normal	0.909106449	-0.03152005	normal	[C]	Energy production and conversion	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: heme binding (GO:0020037);; 	"K00413|0|ptr:472893|CYC1; cytochrome c1, heme protein, mitochondrial; K00413 ubiquinol-cytochrome c reductase cytochrome c1 subunit (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Cytochrome C1 family	"Cytochrome c1, heme protein, mitochondrial (Precursor) GN=CYC1 OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"cytochrome c1, heme protein, mitochondrial [Bos taurus] "
ENSG00000179094(PER1)	--	47.82838356	1415	46.19136003	1267	44.60793265	1321	32.8256157	879	25.81096606	884	26.82308019	794	0.003821553	-0.716701719	normal	0.207712287	-0.539948752	normal	0.002167217	-0.741603826	normal	4.62E-06	-0.668094574	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K02633|0|hsa:5187|PER1, PER, RIGUI, hPER; period circadian clock 1; K02633 period circadian protein (A)"	Circadian rhythm (ko04710);; Circadian entrainment (ko04713);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Period protein 2/3C-terminal region;; PAS domain;; PAS fold;; PAS fold	Period circadian protein homolog 1 GN=PER1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: period circadian protein homolog 1 [Camelus ferus]
ENSG00000179097(HTR1F)	--	0.0684026	3	0.0456623	2	0	0	0.0892624	4	0.131996	5	0.0224573	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04153|0|ptr:470863|HTR1F, 5-HT-1F, 5-HT1F; 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled; K04153 5-hydroxytryptamine receptor 1 (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Serotonergic synapse (ko04726)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srx	5-hydroxytryptamine receptor 1F GN=HTR1F OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: 5-hydroxytryptamine receptor 1F [Eptesicus fuscus]
ENSG00000179104(TMTC2)	--	3.60784227	299	2.581169863	202	2.552041606	224	3.285632247	288	3.59199958	313	3.519622675	330	0.964556372	-0.084466636	normal	0.231831517	0.606705037	normal	0.375073855	0.54761157	normal	0.201603326	0.339923496	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	--	--	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Domain of unknown function (DUF1736);; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; NMDA receptor-regulated protein 1;; Dolichyl-phosphate-mannose-protein mannosyltransferase;; Tetratricopeptide repeat"	Transmembrane and TPR repeat-containing protein 2 GN=TMTC2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: transmembrane and TPR repeat-containing protein 2 isoform X1 [Bubalus bubalis] 
ENSG00000179111(HES7)	--	7.16529083	146	2.431610102	82	4.795255285	123	4.886085898	160	6.730951577	158	2.144173037	77	0.964522239	0.100263193	normal	0.02929062	0.91247617	normal	0.50487999	-0.673458987	normal	0.858651877	0.14767162	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09087|1.06662e-88|hsa:84667|HES7, SCDO4, bHLHb37; hes family bHLH transcription factor 7; K09087 hairy and enhancer of split 2/6/7 (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain;; Hairy Orange	Transcription factor HES-7 GN=HES7 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor HES-7 isoform X2 [Pteropus alecto]
ENSG00000179115(FARSA)	--	41.57584022	1418	41.44329594	1369	42.2373367	1426	46.5659246	1517	47.23121694	1492	40.79176793	1329	0.982393195	0.066461662	normal	0.979555097	0.102589955	normal	0.97890691	-0.109803668	normal	0.948073478	0.020672749	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: tRNA binding (GO:0000049);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: tRNA aminoacylation (GO:0043039);; 	K01889|0|mcf:101866236|uncharacterized LOC101866236; K01889 phenylalanyl-tRNA synthetase alpha chain [EC:6.1.1.20] (A)	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class II core domain (F);; tRNA synthetase class II core domain (G, H, P, S and T);; tRNA synthetases class II (D, K and N);; HTH domain"	Phenylalanine--tRNA ligase alpha subunit GN=FARSA OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: phenylalanine--tRNA ligase alpha subunit isoform X1 [Galeopterus variegatus]
ENSG00000179119(SPTY2D1)	--	8.71612	958	7.88538	865	7.68328	833	9.28221	1021	9.50601	1040	8.09109	890	0.978000043	0.060958337	normal	0.940673024	0.243995442	normal	0.97475346	0.087044493	normal	0.562271197	0.130263367	normal	--	--	--	"K15193|0|hsa:144108|SPTY2D1; SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae); K15193 protein SPT2 (A)"	--	--	--	SPT2 chromatin protein	Protein SPT2 homolog GN=SPTY2D1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein SPT2 homolog [Ovis aries]
ENSG00000179133(C10orf67)	--	0.0812375	4	0.0768834	3	0.154865605	3	0.12132342	6	0.138705252	6	0.155150089	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C10orf67 GN=C10orf67 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: girdin-like [Tupaia chinensis]
ENSG00000179134(SAMD4B)	--	44.11700442	3712	45.157527	3970	48.07754552	3809	45.22864904	3867	44.62184	3575	39.47111835	3598	0.991700554	0.028174365	normal	0.98475121	-0.172553017	normal	0.99015191	-0.090471579	normal	0.739931605	-0.079222512	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[JT]	"Translation, ribosomal structure and biogenesis;; Signal transduction mechanisms"	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; PHAT	Protein Smaug homolog 2 GN=SAMD4B OS=Homo sapiens (Human) PE=1 SV=1	JT	"Translation, ribosomal structure and biogenesis;; Signal transduction mechanisms"	PREDICTED: protein Smaug homolog 2 isoform X1 [Galeopterus variegatus]
ENSG00000179151(EDC3)	--	9.439784	575	9.866861	624	10.74788438	617	8.52893	559	11.07451027	670	9.159287553	578	0.970754846	-0.071352555	normal	0.971003563	0.080999043	normal	0.968869932	-0.102233492	normal	0.937734595	-0.028137277	normal	--	--	--	"K12615|0|hsa:80153|EDC3, LSM16, YJDC, YJEFN2; enhancer of mRNA decapping 3; K12615 enhancer of mRNA-decapping protein 3 (A)"	RNA degradation (ko03018)	[S]	Function unknown	YjeF-related protein N-terminus;; FDF domain;; Scd6-like Sm domain	Enhancer of mRNA-decapping protein 3 GN=EDC3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: enhancer of mRNA-decapping protein 3 [Lipotes vexillifer]
ENSG00000179152(TCAIM)	--	6.864260761	243	7.0663744	237	7.284419118	270	9.292683164	345	8.64605351	319	9.658947326	379	0.60348965	0.472290478	normal	0.777943152	0.405007988	normal	0.561029917	0.478673676	normal	0.05408269	0.455049134	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4461);; Domain of unknown function (DUF4460)	"T-cell activation inhibitor, mitochondrial GN=TCAIM OS=Homo sapiens (Human) PE=2 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: T-cell activation inhibitor, mitochondrial [Ceratotherium simum simum]"
ENSG00000179163(FUCA1)	--	10.8039	374	9.46104	329	8.42114	290	12.31718	428	13.09405	451	11.69106	404	0.955528533	0.163113554	normal	0.677155631	0.431911321	normal	0.58112278	0.467934459	normal	0.131859041	0.348036288	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: alpha-L-fucosidase activity (GO:0004560);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K01206|0|hsa:2517|FUCA1, FUCA; fucosidase, alpha-L- 1, tissue (EC:3.2.1.51); K01206 alpha-L-fucosidase [EC:3.2.1.51] (A)"	Other glycan degradation (ko00511);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	Alpha-L-fucosidase	Tissue alpha-L-fucosidase (Precursor) GN=FUCA1 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: tissue alpha-L-fucosidase [Galeopterus variegatus]
ENSG00000179165(PXT1)	--	0.0285749	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Peroxisomal testis-specific protein 1	Peroxisomal testis-specific protein 1 GN=PXT1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: peroxisomal testis-specific protein 1 [Galeopterus variegatus]
ENSG00000179168(GGN)	--	1.622935425	40	2.08918976	57	1.265054717	29	0.904442056	15	0.997281	32	1.389150323	32	0.291592955	-1.357557091	normal	0.71812531	-0.824715688	normal	0.983783301	0.127400935	normal	0.284497632	-0.693467669	normal	--	--	Biological Process: double-strand break repair (GO:0006302);; Biological Process: gamete generation (GO:0007276);; 	--	--	--	--	--	Gametogenetin GN=GGN OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: gametogenetin [Odobenus rosmarus divergens]
ENSG00000179178(TMEM125)	--	0.035110876	1	0.033990113	1	0	0	0	0	0.034695166	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMEM125 protein family	Transmembrane protein 125 GN=TMEM125 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 125 [Galeopterus variegatus]
ENSG00000179218(CALR)	--	360.5569293	15530	332.2530591	14287	334.454831	14411	436.7699319	18806	396.4403229	16975	383.2014133	16509	0.991460268	0.245280852	normal	0.992181014	0.227259916	normal	0.994455873	0.18777242	normal	0.293659476	0.219925581	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: protein folding (GO:0006457);; Molecular Function: unfolded protein binding (GO:0051082);; 	K08057|0|ptr:455756|CALR; calreticulin; K08057 calreticulin (A)	Protein processing in endoplasmic reticulum (ko04141);; Phagosome (ko04145);; Antigen processing and presentation (ko04612);; Chagas disease (American trypanosomiasis) (ko05142);; HTLV-I infection (ko05166)	[O]	"Posttranslational modification, protein turnover, chaperones"	Calreticulin family	Calreticulin (Precursor) GN=CALR OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: calreticulin [Ursus maritimus]
ENSG00000179222(MAGED1)	--	46.23183032	2780	41.77313989	2487	41.51913	2484	49.51164216	2943	64.022489	3823	48.616042	2929	0.989328235	0.051342816	normal	0.080758733	0.598576461	normal	0.969930219	0.229322871	normal	0.167018647	0.30171749	normal	--	--	--	"K12464|0|nle:100585204|MAGED1; melanoma antigen family D, 1; K12464 melanoma-associated antigen D1 (A)"	Neurotrophin signaling pathway (ko04722)	[S]	Function unknown	MAGE family	Melanoma-associated antigen D1 GN=MAGED1 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	hypothetical protein PANDA_021336 [Ailuropoda melanoleuca]
ENSG00000179240(RP11-111M22.2)	--	2.556433	273	2.0414442	243	2.728499	275	1.5745753	173	1.9664238	254	2.253776293	256	0.102512024	-0.684079545	normal	0.965352782	0.042188813	normal	0.961946906	-0.110946739	normal	0.464227679	-0.231637613	normal	--	--	--	--	--	--	--	Winged helix-turn helix;; Homeodomain-like domain	Putative uncharacterized protein FLJ37770 OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	"hypothetical protein M91_09003, partial [Bos mutus]"
ENSG00000179241(LDLRAD3)	--	12.68711236	767	9.094516926	543	9.732693146	601	9.925344871	620	9.729841781	575	8.115273816	497	0.848600681	-0.337038008	normal	0.970592555	0.06101805	normal	0.907564717	-0.281630058	normal	0.520746173	-0.197512632	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A	Low-density lipoprotein receptor class A domain-containing protein 3 (Precursor) GN=LDLRAD3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor class A domain-containing protein 3 isoform X1 [Bos taurus]
ENSG00000179242(CDH4)	--	2.028929986	280	1.563567237	214	1.204937625	167	2.665388038	365	4.251631644	570	3.345802718	468	0.84752867	0.349951408	normal	1.54E-10	1.385691346	up	3.18E-11	1.470068232	up	0.002376652	1.064857542	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06797|0|mcf:102134154|CDH4; cadherin 4, type 1, R-cadherin (retinal); K06797 cadherin 4, type 1, R-cadherin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin prodomain like	Cadherin-4 (Precursor) GN=CDH4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: cadherin-4 isoform X1 [Bos taurus] 
ENSG00000179256(SMCO3)	--	0.0589317	2	0.118449	4	0	0	0.0877231	3	0.0284264	0	0.0581912	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF4533)	Single-pass membrane and coiled-coil domain-containing protein 3 GN=SMCO3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C12orf69 homolog [Dasypus novemcinctus]
ENSG00000179262(RAD23A)	--	31.22304316	1148	31.83883812	1161	34.81798699	1295	27.48051567	1010	27.81632501	1018	28.59563596	1059	0.954923129	-0.215292143	normal	0.956642015	-0.210763532	normal	0.909051094	-0.298155237	normal	0.17486806	-0.244233538	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: damaged DNA binding (GO:0003684);; Molecular Function: protein binding (GO:0005515);; Biological Process: nucleotide-excision repair (GO:0006289);; Biological Process: proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161);; 	K10839|0|cjc:100402325|RAD23A; RAD23 homolog A (S. cerevisiae); K10839 UV excision repair protein RAD23 (A)	Nucleotide excision repair (ko03420);; Protein processing in endoplasmic reticulum (ko04141)	[L]	"Replication, recombination and repair"	XPC-binding domain;; UBA/TS-N domain;; Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like	UV excision repair protein RAD23 homolog A GN=RAD23A OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: UV excision repair protein RAD23 homolog A isoform X1 [Galeopterus variegatus]
ENSG00000179271(GADD45GIP1)	--	29.0904	1054	26.8153	1011	28.4001	1067	29.7178	1086	26.8144	964	26.5395	967	0.980272816	0.01229931	normal	0.975750394	-0.089966668	normal	0.969762086	-0.150040342	normal	0.766706621	-0.075478842	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: cell cycle (GO:0007049);; 	--	--	[WV]	Extracellular structures;; Defense mechanisms	Growth arrest and DNA-damage-inducible proteins-interacting protein 1	Growth arrest and DNA damage-inducible proteins-interacting protein 1 GN=GADD45GIP1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: growth arrest and DNA damage-inducible proteins-interacting protein 1 [Galeopterus variegatus]
ENSG00000179284(DAND5)	--	0.142083247	4	0.31831175	10	0.18773581	5	0	0	0.06293388	1	0.09577733	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	DAN domain	DAN domain family member 5 (Precursor) GN=DAND5 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: DAN domain family member 5 [Galeopterus variegatus]
ENSG00000179292(TMEM151A)	--	4.439736	184	3.276491055	140	4.014711	172	1.672423	68	1.673267389	70	1.275079881	54	1.03E-06	-1.446224949	down	0.013653549	-1.005749775	normal	4.57E-08	-1.652301139	down	6.20E-06	-1.390852801	down	--	--	--	--	--	--	--	TMEM151 family	Transmembrane protein 151A GN=TMEM151A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 151A [Ceratotherium simum simum]
ENSG00000179295(PTPN11)	--	47.11571903	5088	47.68122324	5251	50.21326106	5507	57.01514942	6294	49.90698717	5465	53.53400729	5980	0.971398311	0.275971205	normal	0.993388112	0.036192525	normal	0.992383601	0.110558292	normal	0.507485362	0.141510445	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K07293|0|cfa:477488|PTPN11, SHP-2; protein tyrosine phosphatase, non-receptor type 11; K07293 tyrosine-protein phosphatase non-receptor type 11 [EC:3.1.3.48] (A)"	Ras signaling pathway (ko04014);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Adipocytokine signaling pathway (ko04920);; Herpes simplex infection (ko05168);; Proteoglycans in cancer (ko05205);; Renal cell carcinoma (ko05211);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; SH2 domain;; Dual specificity phosphatase, catalytic domain"	Tyrosine-protein phosphatase non-receptor type 11 GN=PTPN11 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 11 isoform X1 [Equus przewalskii]
ENSG00000179299(NSUN7)	--	0.839815951	44	0.547304482	23	1.039117631	37	1.044471	47	1.5043243	71	0.587263792	28	0.979992743	0.062222602	normal	0.002824424	1.544178209	up	0.972894494	-0.391919275	normal	0.58418995	0.467657562	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	--	--	NOL1/NOP2/sun family	Putative methyltransferase NSUN7 GN=NSUN7 OS=Homo sapiens (Human) PE=2 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: putative methyltransferase NSUN7 [Ceratotherium simum simum]
ENSG00000179300(ZCCHC5)	--	0	0	0	0	0	0	0.0364134	2	0.0350024	1	0.0178099	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	Zinc knuckle	Zinc finger CCHC domain-containing protein 5 GN=ZCCHC5 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger CCHC domain-containing protein 5 [Ceratotherium simum simum]
ENSG00000179304(FAM156B)	--	0.099210323	2	0.0195552	1	0	0	0.60646582	10	0.06747789	0	0.34734496	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: methylated histone binding (GO:0035064);; 	--	--	--	--	PGC7/Stella/Dppa3 domain	Protein FAM156A/FAM156B GN=FAM156B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM156A/FAM156B [Galeopterus variegatus]
ENSG00000179314(WSCD1)	--	4.00387069	247	4.882294205	282	4.991903332	230	5.604489573	305	3.888962315	241	4.941236948	268	0.918413632	0.271941457	normal	0.929997038	-0.246656021	normal	0.943863889	0.211021183	normal	0.84356216	0.078971083	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	--	--	[GO]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	WSC domain;; Sulfotransferase domain	WSC domain-containing protein 1 GN=WSCD1 OS=Homo sapiens (Human) PE=2 SV=1	GO	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: WSC domain-containing protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000179331(RAB39A)	--	1.207348	83	1.879566	144	1.496559	136	0.547535	46	0.327964	24	0.38256	26	0.379639765	-0.860592841	normal	1.00E-13	-2.532557009	down	9.96E-12	-2.329430476	down	2.94E-05	-1.941918686	down	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07924|3.77667e-160|pps:100985066|RAB39A; RAB39A, member RAS oncogene family; K07924 Ras-related protein Rab-39A (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Ras-related protein Rab-39A GN=RAB39A OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-39A [Loxodonta africana]
ENSG00000179335(CLK3)	--	15.72236545	580	20.981846	726	19.72691943	680	24.0616768	674	21.31310708	715	18.48031564	664	0.954758164	0.185407512	normal	0.974398772	-0.043361846	normal	0.974260923	-0.042547188	normal	0.940283296	0.026698942	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08823|0|hsa:1198|CLK3, PHCLK3, PHCLK3/152; CDC-like kinase 3 (EC:2.7.12.1); K08823 CDC-like kinase [EC:2.7.12.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Dual specificity protein kinase CLK3 GN=CLK3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: dual specificity protein kinase CLK3 [Galeopterus variegatus]
ENSG00000179348(GATA2)	--	6.075738084	389	2.225551749	131	4.344913197	282	1.513136659	87	2.703669544	112	1.773451602	95	0	-2.17161751	down	0.947121697	-0.244439233	normal	6.19E-10	-1.562831085	down	0.073117127	-1.468264738	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K17894|0|pps:100982280|GATA2; GATA binding protein 2; K17894 GATA-binding protein 2 (A)	--	[K]	Transcription	GATA zinc finger	Endothelial transcription factor GATA-2 GN=GATA2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: endothelial transcription factor GATA-2 isoform 1 [Odobenus rosmarus divergens]
ENSG00000179361(ARID3B)	--	1.728206218	156	1.701777459	154	1.404532159	128	1.125064595	100	1.074862823	96	0.93201498	84	0.376108376	-0.664136446	normal	0.31275606	-0.69452887	normal	0.631236985	-0.607055047	normal	0.050859862	-0.667519217	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	ARID/BRIGHT DNA binding domain	AT-rich interactive domain-containing protein 3B GN=ARID3B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 3B isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000179364(PACS2)	--	15.040024	1452	14.3157601	1468	15.6230746	1500	12.229508	1267	12.77869302	1307	15.539472	1625	0.95564913	-0.227199568	normal	0.967170683	-0.188813101	normal	0.98070237	0.107082028	normal	0.677980916	-0.094406926	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PACS-1 cytosolic sorting protein	Phosphofurin acidic cluster sorting protein 2 GN=PACS2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: phosphofurin acidic cluster sorting protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000179387(ELMOD2)	--	10.89457606	586	11.54202124	576	10.23649627	523	11.9288172	658	13.63892193	690	13.38715281	707	0.964898286	0.136017991	normal	0.935501648	0.238528168	normal	0.646525359	0.425545662	normal	0.196941423	0.265248182	normal	--	--	--	--	--	[S]	Function unknown	ELMO/CED-12 family	ELMO domain-containing protein 2 GN=ELMOD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	ELMO domain-containing protein 2 [Bos taurus] 
ENSG00000179388(EGR3)	--	0.080858083	2	0.043840527	3	0	0	0	0	0.039395709	1	0.039715886	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K12497|0|ptr:464048|EGR3; early growth response 3; K12497 early growth response protein 3 (A)	Hepatitis B (ko05161);; Viral carcinogenesis (ko05203)	[R]	General function prediction only	"Zinc-finger double domain;; Domain of unknown function (DUF3446);; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Early growth response protein 3 GN=EGR3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	TPA: early growth response 3-like [Bos taurus]
ENSG00000179397(C1orf101)	--	0.077934997	4	0.043650871	2	0.102132838	4	0.141307273	7	0.059571505	2	0.104712445	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: CatSper complex (GO:0036128);; 	--	--	--	--	Cation channel sperm-associated protein subunit delta	Uncharacterized protein C1orf101 (Precursor) GN=C1orf101 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf101 homolog [Sus scrofa]
ENSG00000179399(GPC5)	--	0	0	0	0	0.0678347	1	0	0	0.01953073	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Cellular Component: membrane (GO:0016020);; Molecular Function: heparan sulfate proteoglycan binding (GO:0043395);; 	K08111|0|hsa:2262|GPC5; glypican 5; K08111 glypican 5 (A)	--	[T]	Signal transduction mechanisms	Glypican	Secreted glypican-5 (Precursor) GN=GPC5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: glypican-5 [Ceratotherium simum simum]
ENSG00000179403(VWA1)	--	18.41466725	998	15.45590408	734	14.605039	705	8.335860272	388	12.16030091	548	7.832825955	360	8.20E-13	-1.390248543	down	0.600534907	-0.441972748	normal	1.14E-05	-0.974935191	normal	0.002918783	-0.932509135	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[W]	Extracellular structures	von Willebrand factor type A domain;; Fibronectin type III domain;; von Willebrand factor type A domain	von Willebrand factor A domain-containing protein 1 (Precursor) GN=VWA1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: von Willebrand factor A domain-containing protein 1 isoform 2 [Odobenus rosmarus divergens]
ENSG00000179409(GEMIN4)	--	27.84303422	1982	27.39941657	1890	27.59303137	1982	30.06405805	2103	29.85404005	2095	20.42553114	1508	0.986284188	0.054618519	normal	0.981650314	0.127040872	normal	0.742671577	-0.402258962	normal	0.848694749	-0.058955854	normal	--	--	--	"K13132|0|hsa:50628|GEMIN4, HC56, HCAP1, HHRF-1, p97; gem (nuclear organelle) associated protein 4; K13132 gem associated protein 4 (A)"	RNA transport (ko03013)	--	--	--	Gem-associated protein 4 GN=GEMIN4 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: gem-associated protein 4 [Equus caballus] 
ENSG00000179431(FJX1)	--	18.1763	661	17.6159	662	17.0072	649	23.2759	857	20.2376	738	15.2274	560	0.84053941	0.343110619	normal	0.966104546	0.135070703	normal	0.942965755	-0.220529353	normal	0.753493309	0.105565972	normal	--	--	--	K16674|0|hsa:24147|FJX1; four jointed box 1 (Drosophila); K16674 four-jointed box protein 1 (A)	--	--	--	Protein of unknown function (DUF1193)	Four-jointed box protein 1 (Precursor) GN=FJX1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: four-jointed box protein 1 [Oryctolagus cuniculus]
ENSG00000179454(KLHL28)	--	4.750005	315	4.84940129	313	4.220677	265	3.165347	204	4.496994	311	4.137850248	288	0.116664044	-0.653619501	normal	0.966679146	-0.03052667	normal	0.961997335	0.111176268	normal	0.60106109	-0.173658559	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10464|0|hsa:54813|KLHL28, BTBD5; kelch-like family member 28; K10464 kelch-like protein 28 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 28 GN=KLHL28 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 28 isoform 1 [Ceratotherium simum simum]
ENSG00000179455(MKRN3)	--	2.100406416	95	2.628812726	124	1.622536	82	2.395383498	111	2.147943	109	2.483972384	117	0.96127878	0.190870184	normal	0.955192766	-0.204772694	normal	0.831967106	0.496812787	normal	0.800759939	0.141390512	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Cellular Component: anaphase-promoting complex (GO:0005680);; Molecular Function: metal ion binding (GO:0046872);; 	"K15687|0|hsa:7681|MKRN3, CPPB2, D15S9, RNF63, ZFP127, ZNF127; makorin ring finger protein 3; K15687 E3 ubiquitin-protein ligase makorin [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; Anaphase-promoting complex subunit 11 RING-H2 finger"	Probable E3 ubiquitin-protein ligase makorin-3 GN=MKRN3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable E3 ubiquitin-protein ligase makorin-3 [Oryctolagus cuniculus]
ENSG00000179456(ZBTB18)	--	6.034769589	491	6.244453689	494	6.800946284	536	11.67001144	931	10.7888228	867	8.699457576	757	6.28E-05	0.890170806	normal	0.001453663	0.788250216	normal	0.408000244	0.488603303	normal	5.92E-06	0.726659933	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 18 GN=ZBTB18 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 18 [Oryctolagus cuniculus]
ENSG00000179476(C14orf28)	--	2.303555606	90	1.970987513	77	1.68744788	66	1.851375071	74	1.765856544	57	2.01639563	80	0.94970116	-0.307433211	normal	0.920699235	-0.445122151	normal	0.960442639	0.263745786	normal	0.800546347	-0.164520455	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C14orf28 GN=C14orf28 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C14orf28 homolog [Equus caballus] 
ENSG00000179477(ALOX12B)	--	0.235066	10	0.302280005	13	0.068253392	2	0.0698462	3	0.204862288	8	0.107288034	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: protein binding (GO:0005515);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K08021|0|hsa:242|ALOX12B, 12R-LOX, ARCI2; arachidonate 12-lipoxygenase, 12R type (EC:1.13.11.-); K08021 arachidonate 12-lipoxygenase (R-type) [EC:1.13.11.-] (A)"	Arachidonic acid metabolism (ko00590);; Serotonergic synapse (ko04726)	--	--	Lipoxygenase;; PLAT/LH2 domain	"Arachidonate 12-lipoxygenase, 12R-type GN=ALOX12B OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: arachidonate 12-lipoxygenase, 12R-type [Ceratotherium simum simum]"
ENSG00000179520(SLC17A8)	--	0.014977654	1	0	0	0.044554913	2	0	0	0.029215595	1	0.044750752	3	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12302|0|ggo:101142214|SLC17A8; vesicular glutamate transporter 3 isoform 1; K12302 MFS transporter, ACS family, solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6/7/8 (A)"	Synaptic vesicle cycle (ko04721);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Nicotine addiction (ko05033)	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily	Vesicular glutamate transporter 3 GN=SLC17A8 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: vesicular glutamate transporter 3 isoform X1 [Pteropus alecto]
ENSG00000179526(SHARPIN)	--	23.2943	675	23.356971	699	21.482336	662	31.27977	907	34.413694	1029	33.57269	985	0.731436261	0.394605532	normal	0.231554547	0.535491735	normal	0.137243833	0.563938199	normal	0.001979713	0.499754058	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Zn-finger in Ran binding protein and others	Sharpin GN=SHARPIN OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: sharpin [Equus caballus]
ENSG00000179528(LBX2)	--	4.054661	67	4.144428	78	5.791361	105	3.203188	68	3.182254488	57	4.607037	91	0.975430378	-0.009248107	normal	0.912505579	-0.463384113	normal	0.959537864	-0.211467779	normal	0.689284357	-0.230590646	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09353|2.53062e-137|hsa:85474|LBX2; ladybird homeobox 2; K09353 homeobox protein LBX (A)	--	[R]	General function prediction only	Homeobox domain	Transcription factor LBX2 GN=LBX2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	Lbx2 [Sus scrofa]
ENSG00000179532(DNHD1)	--	3.054293889	516	2.714969	579	2.030333	423	1.72151	307	1.456185	287	3.125014	556	0.004163761	-0.776929212	normal	6.83E-06	-1.03003633	down	0.767560046	0.38493186	normal	0.406125815	-0.42039285	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Biological Process: microtubule-based movement (GO:0007018);; Cellular Component: dynein complex (GO:0030286);; 	--	--	[Z]	Cytoskeleton	"Dynein heavy chain, N-terminal region 2;; Dynein heavy chain and region D6 of dynein motor;; Microtubule-binding stalk of dynein motor;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D3;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA)"	Dynein heavy chain domain-containing protein 1 GN=UNQ5781/PRO12970 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: dynein heavy chain domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000179542(SLITRK4)	--	0.153192227	16	0.169128927	10	0.068203616	5	0.087126745	6	0.165335525	12	0.036787264	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat	SLIT and NTRK-like protein 4 (Precursor) GN=SLITRK4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: SLIT and NTRK-like protein 4-like [Tupaia chinensis]
ENSG00000179562(GCC1)	--	10.0487	907	10.4818	971	8.43374	777	9.41749	854	10.6603	954	13.4899	1217	0.972056894	-0.117493579	normal	0.97780568	-0.046834996	normal	0.028848523	0.63805084	normal	0.624077398	0.167755358	normal	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	GRIP domain	GRIP and coiled-coil domain-containing protein 1 GN=GCC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: GRIP and coiled-coil domain-containing protein 1 [Felis catus]
ENSG00000179564(LSMEM2)	--	0.0831621	2	0.0404497	1	0.120116	2	0	0	0.202254	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Leucine-rich single-pass membrane protein 2 GN=LSMEM2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich single-pass membrane protein 2 isoform X4 [Oryctolagus cuniculus]
ENSG00000179580(RNF151)	--	0.09900925	1	0	0	0	0	0	0	0.09536261	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[T]	Signal transduction mechanisms	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; TRAF-type zinc finger;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; U-box domain"	RING finger protein 151 GN=RNF151 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: RING finger protein 151 [Leptonychotes weddellii]
ENSG00000179583(CIITA)	--	0.057397732	11	0.088162078	17	0.112829264	21	0.089350336	17	0.106879744	21	0.103497729	22	--	--	--	0.986708894	0.262397803	normal	0.988046157	0.054955945	normal	0.800386331	0.272487209	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08060|0|hsa:4261|CIITA, C2TA, CIITAIV, MHC2TA, NLRA; class II, major histocompatibility complex, transactivator (EC:2.7.11.1); K08060 class II, major histocompatibility complex, transactivator (A)"	Antigen processing and presentation (ko04612);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Influenza A (ko05164);; Primary immunodeficiency (ko05340)	--	--	NACHT domain;; Leucine Rich repeat;; Leucine Rich repeats (2 copies)	MHC class II transactivator GN=CIITA OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: MHC class II transactivator [Galeopterus variegatus]
ENSG00000179588(ZFPM1)	--	5.0022146	479	4.69398222	456	4.52494204	461	3.367356704	313	3.889175	357	3.7788925	364	0.067979992	-0.642126278	normal	0.802777522	-0.373133878	normal	0.839744783	-0.347832521	normal	0.030206963	-0.453783191	normal	[R]	General function prediction only	--	"K17441|0|hsa:161882|ZFPM1, FOG, FOG1, ZC2HC11A, ZNF408, ZNF89A; zinc finger protein, FOG family member 1; K17441 zinc finger protein ZFPM1 (A)"	--	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; Zinc finger, C2H2 type;; Zinc-finger double domain"	Zinc finger protein ZFPM1 GN=ZFPM1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein ZFPM1 [Orcinus orca]
ENSG00000179593(ALOX15B)	--	0	0	0	0	0	0	0	0	0.037353015	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: protein binding (GO:0005515);; Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Molecular Function: metal ion binding (GO:0046872);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K08022|0|pps:100971127|ALOX15B; arachidonate 15-lipoxygenase, type B; K08022 arachidonate 15-lipoxygenase (second type) / 8-lipoxygenase (S-type) [EC:1.13.11.33 1.13.11.-] (A)"	Arachidonic acid metabolism (ko00590);; Serotonergic synapse (ko04726)	--	--	Lipoxygenase;; PLAT/LH2 domain	Arachidonate 15-lipoxygenase B GN=ALOX15B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: arachidonate 15-lipoxygenase B-like isoform 2 [Ceratotherium simum simum]
ENSG00000179598(PLD6)	--	8.09264	323	8.24275	336	5.52073	224	5.33945	215	5.3068	211	6.68196	269	0.18688766	-0.614420457	normal	0.066759781	-0.688696079	normal	0.929036888	0.254247618	normal	0.271634135	-0.366590135	normal	[I]	Lipid transport and metabolism	--	"K16862|1.91586e-141|hsa:201164|PLD6, ZUC; phospholipase D family, member 6 (EC:3.1.4.4); K16862 mitochondrial cardiolipin hydrolase [EC:3.1.4.-] (A)"	--	--	--	PLD-like domain	Mitochondrial cardiolipin hydrolase GN=PLD6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: mitochondrial cardiolipin hydrolase [Odobenus rosmarus divergens]
ENSG00000179603(GRM8)	--	0	0	0	0	0.16118602	0	0.0129315	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04608|0|hsa:2918|GRM8, GLUR8, GPRC1H, MGLUR8, mGlu8; glutamate receptor, metabotropic 8; K04608 metabotropic glutamate receptor 6/7/8 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Nine Cysteines Domain of family 3 GPCR;; Periplasmic binding protein	Metabotropic glutamate receptor 8 (Precursor) GN=GRM8 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: metabotropic glutamate receptor 8 isoform X2 [Galeopterus variegatus]
ENSG00000179604(CDC42EP4)	--	26.46068003	1637	22.44967	1416	26.947763	1653	27.160402	1574	24.838538	1468	22.88356463	1393	0.982346651	-0.087367409	normal	0.9829451	0.030572078	normal	0.946685224	-0.254928516	normal	0.629022553	-0.10695726	normal	--	--	--	--	--	--	--	Cdc42 effector;; P21-Rho-binding domain	Cdc42 effector protein 4 GN=CDC42EP4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cdc42 effector protein 4 [Loxodonta africana]
ENSG00000179627(ZBTB42)	--	2.497059	170	2.392037	173	1.77982417	135	1.268615811	90	1.801742249	132	1.1332506	77	0.013035008	-0.936532146	normal	0.849678947	-0.407568467	normal	0.161806564	-0.806206105	normal	0.0318767	-0.698619922	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 42 GN=ZBTB42 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 42 [Equus caballus]
ENSG00000179630(LACC1)	--	3.013498	212	3.671742	260	4.063239853	249	3.308034647	234	3.182139939	216	4.275655	268	0.96191693	0.110847184	normal	0.912612556	-0.287071951	normal	0.963230616	0.097226527	normal	0.960050947	-0.026783856	normal	[S]	Function unknown	--	"K05810|0|hsa:144811|LACC1, C13orf31; laccase (multicopper oxidoreductase) domain containing 1; K05810 conserved hypothetical protein (A)"	--	--	--	Multi-copper polyphenol oxidoreductase laccase	Laccase domain-containing protein 1 GN=LACC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: laccase domain-containing protein 1 [Galeopterus variegatus]
ENSG00000179632(MAF1)	--	71.83203794	2440	64.2159187	2227	70.605515	2437	77.9819051	2644	81.21412301	2773	99.333846	3387	0.987233707	0.084957368	normal	0.940125161	0.294739828	normal	0.545091996	0.46636374	normal	0.118701319	0.289172384	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: negative regulation of transcription from RNA polymerase III promoter (GO:0016480);; 	--	--	[K]	Transcription	Maf1 regulator	Repressor of RNA polymerase III transcription MAF1 homolog GN=MAF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: repressor of RNA polymerase III transcription MAF1 homolog [Eptesicus fuscus]
ENSG00000179639(FCER1A)	--	0	0	0	0	0	0	0	0	0	0	0.093334737	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K08089|0|hsa:2205|FCER1A, FCE1A, FcERI; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; K08089 Fc receptor, IgE, high affinity I, alpha polypeptide (A)"	Sphingolipid signaling pathway (ko04071);; Fc epsilon RI signaling pathway (ko04664);; Asthma (ko05310)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain	High affinity immunoglobulin epsilon receptor subunit alpha (Precursor) GN=FCER1A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: high affinity immunoglobulin epsilon receptor subunit alpha [Galeopterus variegatus]
ENSG00000179673(RPRML)	--	0.373975	5	0.775275	11	0.34228	4	0.218347	3	0.215444	2	0.146477	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Reprimo-like protein GN=RPRML OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: reprimo-like protein [Condylura cristata]
ENSG00000179674(ARL14)	--	0.313345	7	0.267523	6	0.0891475	1	1.15587	26	1.13587	25	0.71397	16	0.469400497	1.66243591	normal	0.356997995	1.800679255	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K17200|4.17614e-141|hsa:80117|ARL14, ARF7; ADP-ribosylation factor-like 14; K17200 ADP-ribosylation factor-like protein 14 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; G-protein alpha subunit;; Miro-like protein;; Gtr1/RagA G protein conserved region;; Signal recognition particle receptor beta subunit;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	ADP-ribosylation factor-like protein 14 GN=ARL14 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 14 [Felis catus]
ENSG00000179698(WDR97)	--	0.3356754	45	0.497344129	70	0.3847326	52	0.190566665	26	0.318886432	43	0.436495446	60	0.860682897	-0.786481246	normal	0.758879098	-0.704823537	normal	0.97264813	0.192932064	normal	0.533599114	-0.391518681	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"WD domain, G-beta repeat"	WD repeat-containing protein KIAA1875 GN=KIAA1875 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: WD repeat-containing protein KIAA1875 homolog [Ceratotherium simum simum]
ENSG00000179715(PCED1B)	--	9.815194	231	9.633400001	236	5.487189	142	182.384581	3780	212.20654	4161	247.538565	5000	0	3.992719432	up	0	4.110026007	up	0	5.1148717	up	2.03E-52	4.388204414	up	--	--	--	--	--	--	--	GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p	PC-esterase domain-containing protein 1B GN=PCED1B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: PC-esterase domain-containing protein 1B isoform X2 [Pteropus alecto] 
ENSG00000179761(PIPOX)	--	0.137012616	4	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00306|0|hsa:51268|PIPOX, LPIPOX; pipecolic acid oxidase (EC:1.5.3.1 1.5.3.7); K00306 sarcosine oxidase / L-pipecolate oxidase [EC:1.5.3.1 1.5.3.7] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Lysine degradation (ko00310);; Peroxisome (ko04146)"	[R]	General function prediction only	FAD dependent oxidoreductase;; NAD(P)-binding Rossmann-like domain	Peroxisomal sarcosine oxidase GN=PIPOX OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	peroxisomal sarcosine oxidase [Oryctolagus cuniculus] 
ENSG00000179772(FOXS1)	--	0	0	0	0	0	0	0.00303345	0	0.235272	4	3.73E-05	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09412|0|hsa:2307|FOXS1, FKHL18, FREAC10; forkhead box S1; K09412 forkhead-like 18 protein (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein S1 GN=FOXS1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: forkhead box protein S1 [Canis lupus familiaris]
ENSG00000179774(ATOH7)	--	0.337492	6	0	0	0.106547	1	0.165479	3	0.108167	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09083|3.23051e-77|ptr:466090|ATOH7; atonal homolog 7 (Drosophila); K09083 atonal protein 1/7 (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Protein atonal homolog 7 GN=ATOH7 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: protein atonal homolog 7 [Orcinus orca]
ENSG00000179776(CDH5)	--	0.098127453	5	0.066580438	4	0.08958183	4	0.353733788	14	0.116318032	10	0.513206446	37	--	--	--	--	--	--	0.000216395	2.797604689	up	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K06533|0|hsa:1003|CDH5, 7B4, CD144; cadherin 5, type 2 (vascular endothelium); K06533 cadherin 5, type 2, VE-cadherin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Leukocyte transendothelial migration (ko04670)	[S]	Function unknown	Cadherin domain;; Cadherin cytoplasmic region;; Cadherin-like	Cadherin-5 (Precursor) GN=CDH5 OS=Homo sapiens (Human) PE=1 SV=5	S	Function unknown	PREDICTED: cadherin-5 [Odobenus rosmarus divergens]
ENSG00000179820(MYADM)	--	148.6377614	5122	128.61619	4826	135.3611607	4873	105.8789094	3920	85.1745612	2928	95.65541137	3143	0.791300969	-0.416542542	normal	0.00213941	-0.742037101	normal	0.026717062	-0.640709768	normal	4.37E-05	-0.590953681	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	Myeloid-associated differentiation marker GN=MYADM OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: myeloid-associated differentiation marker [Felis catus] 
ENSG00000179832(MROH1)	--	6.1846928	731	5.7558373	788	7.38990703	744	8.517289492	1014	10.1261994	1053	10.129298	1486	0.580339029	0.440492947	normal	0.739359586	0.396151607	normal	1.02E-06	0.988318731	normal	0.035264202	0.63069841	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	HEAT repeats;; HEAT repeat;; HEAT-like repeat	Maestro heat-like repeat-containing protein family member 1 GN=MROH1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: HEAT repeat-containing protein 7A-like [Ceratotherium simum simum]
ENSG00000179833(SERTAD2)	--	9.26777	854	8.98798	819	10.28923	925	7.41322	686	5.98771	554	6.7228	623	0.835552508	-0.346163237	normal	0.117973958	-0.584083761	normal	0.111600659	-0.577354787	normal	0.002517794	-0.501157522	normal	--	--	--	--	--	--	--	SERTA motif	SERTA domain-containing protein 2 GN=SERTAD2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: SERTA domain-containing protein 2 isoform X1 [Tupaia chinensis] 
ENSG00000179841(AKAP5)	--	0.77345378	85	0.813742	88	0.869585	96	0.939105865	109	1.036467	111	0.6184814	70	0.938551388	0.322797967	normal	0.938729326	0.308823353	normal	0.895130036	-0.455532344	normal	0.897319559	0.086322265	normal	--	--	Biological Process: protein targeting (GO:0006605);; Biological Process: signal transduction (GO:0007165);; 	"K16522|0|hsa:9495|AKAP5, AKAP75, AKAP79, H21; A kinase (PRKA) anchor protein 5; K16522 A-kinase anchor protein 5 (A)"	--	--	--	WSK motif;; RII binding domain	A-kinase anchor protein 5 GN=AKAP5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 5 [Galeopterus variegatus]
ENSG00000179846(NKPD1)	--	0.4071169	24	0.450186	27	0.48164	24	0.128807	10	0.2015271	12	0.536901	34	0.877265313	-1.174209377	normal	0.860875011	-1.096971429	normal	0.970744645	0.469256873	normal	0.651659795	-0.439123624	normal	--	--	--	--	--	[R]	General function prediction only	KAP family P-loop domain	NTPase KAP family P-loop domain-containing protein 1 GN=NKPD1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: NTPase KAP family P-loop domain-containing protein 1 [Chrysochloris asiatica]
ENSG00000179855(GIPC3)	--	0.0717016	8	0.0465468	5	0.00894061	0	0.00914934	1	0.0173155	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PDZ domain (Also known as DHR or GLGF)	PDZ domain-containing protein GIPC3 GN=GIPC3 OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PDZ domain-containing protein GIPC3 [Galeopterus variegatus]
ENSG00000179859(AC025335.1)	--	1.90332471	63	1.716419816	67	1.634942	64	1.423079	57	1.541031	57	3.387689558	60	0.972909541	-0.170839528	normal	0.964916006	-0.24853633	normal	0.974834084	-0.098984715	normal	0.799360011	-0.178049406	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	"Domain of unknown function (DUF4632);; zinc-RING finger domain;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	Putative uncharacterized protein FLJ38447 OS=Homo sapiens (Human) PE=5 SV=3	R	General function prediction only	PREDICTED: putative uncharacterized protein FLJ38447 [Oryctolagus cuniculus]
ENSG00000179862(CITED4)	--	41.9784	648	22.9423	368	31.9926	527	54.1514	853	55.2291	865	43.2321	681	0.801001645	0.364963447	normal	4.70E-09	1.208233847	up	0.810340294	0.360647612	normal	0.028853016	0.615094567	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	CITED	Cbp/p300-interacting transactivator 4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	cbp/p300-interacting transactivator 4 [Bos taurus] 
ENSG00000179869(ABCA13)	--	0	0	0	0	0.0069026	1	0	0	0.00333127	0	0.014533469	1	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05647|0|hsa:154664|ABCA13; ATP-binding cassette, sub-family A (ABC1), member 13; K05647 ATP binding cassette, subfamily A (ABC1), member 13 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC transporter;; ABC-2 family transporter protein;; AAA domain	ATP-binding cassette sub-family A member 13 GN=ABCA13 OS=Homo sapiens (Human) PE=2 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: ATP-binding cassette sub-family A member 13 [Ceratotherium simum simum]
ENSG00000179873(NLRP11)	--	0.095901306	5	0.057314718	3	0.057029935	2	0.038195874	2	0	0	0.019075543	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	PAAD/DAPIN/Pyrin domain;; NACHT domain	"NACHT, LRR and PYD domains-containing protein 11 GN=NLRP11 OS=Homo sapiens (Human) PE=2 SV=2"	R	General function prediction only	"PREDICTED: NACHT, LRR and PYD domains-containing protein 11, partial [Galeopterus variegatus]"
ENSG00000179886(TIGD5)	--	6.92957	677	5.47385	553	5.55429	563	6.52638	641	7.65262	745	7.0116	689	0.96916381	-0.109408509	normal	0.70818018	0.407570938	normal	0.908231246	0.282390846	normal	0.398456834	0.189708711	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	DDE superfamily endonuclease;; Tc5 transposase DNA-binding domain;; CENP-B N-terminal DNA-binding domain	Tigger transposable element-derived protein 5 GN=TIGD5 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: tigger transposable element-derived protein 5 [Equus przewalskii]
ENSG00000179889(PDXDC1)	--	31.8865989	1952	33.57394344	2139	31.62594443	1985	42.41505442	2603	46.481492	2821	41.58212102	2450	0.811400725	0.384127403	normal	0.840664912	0.377610495	normal	0.934167113	0.295148547	normal	0.023902768	0.352595161	normal	[E]	Amino acid transport and metabolism	Molecular Function: carboxy-lyase activity (GO:0016831);; Biological Process: carboxylic acid metabolic process (GO:0019752);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	--	--	[E]	Amino acid transport and metabolism	Pyridoxal-dependent decarboxylase conserved domain	Pyridoxal-dependent decarboxylase domain-containing protein 1 GN=PDXDC1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: pyridoxal-dependent decarboxylase domain-containing protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000179902(C1orf194)	--	0.22201	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF3695)	Uncharacterized protein C1orf194 GN=C1orf194 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf194 homolog [Equus caballus]
ENSG00000179909(ZNF154)	--	0.208695	21	0.403857	41	0.187143	18	0.138528	14	0.0674593	6	0.305707	31	0.98109603	-0.564859695	normal	0.000261389	-2.519445671	down	0.9470928	0.728824838	normal	0.592181881	-0.66914663	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7710|ZNF154, pHZ-92; zinc finger protein 154; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; XPA protein N-terminal;; Transcription factor S-II (TFIIS)"	Zinc finger protein 154 GN=ZNF154 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 154 [Pteropus alecto]
ENSG00000179912(R3HDM2)	--	14.142758	1270	11.68708852	978	12.70422211	1150	11.51783385	1055	11.69115735	1061	41.20695219	1308	0.908385783	-0.29802149	normal	0.975686586	0.09594926	normal	0.967788315	0.177218581	normal	0.983948554	-0.009467889	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[A]	RNA processing and modification	R3H domain	R3H domain-containing protein 2 GN=R3HDM2 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: R3H domain-containing protein 2 isoform X8 [Oryctolagus cuniculus]
ENSG00000179913(B3GNT3)	--	4.336694421	201	2.543855055	90	2.547740051	110	7.014475019	290	5.880461042	268	4.793002592	204	0.584074832	0.494860565	normal	3.69E-09	1.537124252	up	0.016258634	0.873817247	normal	0.027436518	0.90370948	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K07970|0|hsa:10331|B3GNT3, B3GAL-T8, B3GN-T3, B3GNT-3, HP10328, TMEM3, beta3Gn-T3; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 (EC:2.4.1.146); K07970 beta-1,3-N-acetylglucosaminyltransferase 3 [EC:2.4.1.-] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 GN=B3GNT3 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 [Galeopterus variegatus]"
ENSG00000179914(ITLN1)	--	0	0	0.0473371	1	0	0	0	0	0.0472065	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17527|0|hsa:55600|ITLN1, HL-1, HL1, INTL, ITLN, LFR, hIntL, omentin; intelectin 1 (galactofuranose binding); K17527 intelectin (A)"	--	--	--	"Fibrinogen beta and gamma chains, C-terminal globular domain"	Intelectin-1 (Precursor) GN=ITLN1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: intelectin-1-like [Oryctolagus cuniculus]
ENSG00000179915(NRXN1)	--	0	0	0.035673632	2	0	0	0.107617632	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07377|0|hsa:9378|NRXN1, Hs.22998, PTHSL2, SCZD17; neurexin 1; K07377 neurexin (A)"	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Laminin G domain;; Laminin G domain;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain;; Syndecan domain	Neurexin-1 (Precursor) GN=NRXN1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: neurexin-1 [Vicugna pacos]
ENSG00000179918(SEPHS2)	--	36.883	1599	41.1776	1829	35.7499	1575	48.2756	2120	46.475	2008	52.5717	2286	0.815632893	0.375747626	normal	0.982329882	0.113188296	normal	0.230405988	0.528758354	normal	0.033040129	0.337260065	normal	--	--	--	"K01008|0|hsa:22928|SEPHS2, SPS2, SPS2b; selenophosphate synthetase 2 (EC:2.7.9.3); K01008 selenide, water dikinase [EC:2.7.9.3] (A)"	Selenocompound metabolism (ko00450)	[T]	Signal transduction mechanisms	"AIR synthase related protein, C-terminal domain;; AIR synthase related protein, N-terminal domain"	"Selenide, water dikinase 2 GN=SEPHS2 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: selenophosphate synthetase 2 [Odobenus rosmarus divergens]
ENSG00000179921(GPBAR1)	--	0	0	0.112649556	3	0.160136258	2	0.201822888	4	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08400|1.31085e-146|ggo:101124421|GPBAR1; G-protein coupled bile acid receptor 1 isoform 1; K08400 G protein-coupled bile acid receptor 1 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	G-protein coupled bile acid receptor 1 GN=GPBAR1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled bile acid receptor 1 [Ochotona princeps]
ENSG00000179922(ZNF784)	--	4.251578	156	3.553530994	138	2.976965257	116	2.514597	91	2.832988	103	2.844399	104	0.110801939	-0.798017788	normal	0.85278216	-0.437875029	normal	0.962760831	-0.163579268	normal	0.200476585	-0.481447013	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 784 GN=ZNF784 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 784 [Orcinus orca]
ENSG00000179930(ZNF648)	--	0.0298964	2	0	0	0	0	0.0149589	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 648 GN=ZNF648 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 648 [Galeopterus variegatus]
ENSG00000179933(C14orf119)	--	39.047308	959	37.2096	979	37.0021	1009	43.8925	1067	42.0645	1030	41.8026	1118	0.973343697	0.122938413	normal	0.978133961	0.051759063	normal	0.972013034	0.139503861	normal	0.654897996	0.104572089	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4508)	Uncharacterized protein C14orf119 GN=C14orf119 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C14orf119 homolog [Orcinus orca] 
ENSG00000179941(BBS10)	--	7.19077	360	7.79368	386	9.61358	467	5.61939	284	5.78012	289	6.64661	333	0.81779271	-0.37114995	normal	0.682069474	-0.43697185	normal	0.46025695	-0.494286996	normal	0.04726856	-0.441314999	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TCP-1/cpn60 chaperonin family	Bardet-Biedl syndrome 10 protein GN=BBS10 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: Bardet-Biedl syndrome 10 protein [Galeopterus variegatus]
ENSG00000179943(FIZ1)	--	15.36015944	609	17.09167939	606	13.90279544	630	11.06839679	433	13.754153	499	16.38678344	625	0.309958174	-0.521339163	normal	0.8918445	-0.30087562	normal	0.97409036	-0.019739508	normal	0.211688712	-0.264868763	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger"	Flt3-interacting zinc finger protein 1 GN=FIZ1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: flt3-interacting zinc finger protein 1 [Pteropus alecto] 
ENSG00000179950(PUF60)	--	127.497509	7259	128.62345	7464	139.643373	7841	140.9736501	8363	148.072807	8330	127.0237188	7798	0.991388156	0.173383273	normal	0.993078272	0.136914684	normal	0.995376213	-0.01622181	normal	0.690662532	0.096956373	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12838|0|pps:100971348|PUF60; poly-U binding splicing factor 60KDa; K12838 poly(U)-binding-splicing factor PUF60 (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Poly(U)-binding-splicing factor PUF60 GN=PUF60 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: poly(U)-binding-splicing factor PUF60 isoform 1 [Ceratotherium simum simum] 
ENSG00000179954(SSC5D)	--	1.288040958	34	0.19133978	21	0.3689618	41	1.06399483	33	3.562746169	54	0.749646516	32	0.983668596	-0.070659675	normal	0.134179237	1.281679491	normal	0.972447761	-0.351146604	normal	0.713453307	0.289703915	normal	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D (Precursor) GN=SSC5D OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: soluble scavenger receptor cysteine-rich domain-containing protein SSC5D [Galeopterus variegatus]
ENSG00000179958(DCTPP1)	--	74.88937663	1402	69.2018471	1345	81.29817297	1560	81.92461213	1545	82.422506	1537	49.70867	928	0.979751888	0.10917423	normal	0.971375824	0.170904575	normal	0.001258283	-0.756678762	normal	0.772036549	-0.125323938	normal	[R]	General function prediction only	Biological Process: nucleoside triphosphate catabolic process (GO:0009143);; Molecular Function: nucleoside-triphosphate diphosphatase activity (GO:0047429);; 	K16904|3.38746e-108|pps:100980571|DCTPP1; dCTP pyrophosphatase 1; K16904 dCTP diphosphatase [EC:3.6.1.12] (A)	Pyrimidine metabolism (ko00240)	--	--	MazG nucleotide pyrophosphohydrolase domain	dCTP pyrophosphatase 1 GN=DCTPP1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: dCTP pyrophosphatase 1 [Odobenus rosmarus divergens]
ENSG00000179965(ZNF771)	--	9.292634	216	8.9172195	226	6.6452004	181	5.8026711	141	6.957555796	169	6.631053507	158	0.267929743	-0.640483369	normal	0.770691163	-0.437329085	normal	0.950486238	-0.20254382	normal	0.161480971	-0.433867842	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; LYAR-type C2HC zinc finger"	Zinc finger protein 771 GN=ZNF771 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 771 isoform X2 [Leptonychotes weddellii]
ENSG00000179981(TSHZ1)	--	2.3625833	258	2.53028012	276	2.246790567	247	3.671215651	389	3.591740005	392	2.69533398	289	0.291281139	0.55883963	normal	0.551185984	0.482530023	normal	0.941510722	0.217037365	normal	0.069327767	0.432096839	normal	--	--	--	"K09236|0|ptr:455478|TSHZ1, ZNF407; teashirt homolog 1; K09236 teashirt (A)"	--	--	--	"C2H2 type zinc-finger (2 copies);; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Teashirt homolog 1 GN=TSHZ1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: teashirt homolog 1 [Leptonychotes weddellii]
ENSG00000179988(PSTK)	--	2.573744393	35	1.379031003	33	2.201316	28	2.675989	40	2.977401	48	1.75761	31	0.980990081	0.155427595	normal	0.94766436	0.500046605	normal	0.984128224	0.131783144	normal	0.713453307	0.287811763	normal	--	--	--	K10837|0|pon:100444035|PSTK; phosphoseryl-tRNA kinase; K10837 O-phosphoseryl-tRNA(Sec) kinase [EC:2.7.1.164] (A)	Selenocompound metabolism (ko00450);; Aminoacyl-tRNA biosynthesis (ko00970)	[R]	General function prediction only	Chromatin associated protein KTI12;; AAA domain;; AAA domain;; AAA domain;; AAA domain;; Adenylylsulphate kinase	L-seryl-tRNA(Sec) kinase GN=PSTK OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: L-seryl-tRNA(Sec) kinase [Equus caballus]
ENSG00000180008(SOCS4)	--	12.730186	1184	13.25371944	1274	14.70854505	1246	10.93686573	1050	11.44049819	1020	12.45813541	1152	0.959278942	-0.203830915	normal	0.858830747	-0.341768234	normal	0.975960444	-0.121301635	normal	0.227578509	-0.2220502	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	"K04697|0|hsa:122809|SOCS4, SOCS7; suppressor of cytokine signaling 4; K04697 suppressor of cytokine signaling 4 (A)"	Jak-STAT signaling pathway (ko04630);; Insulin signaling pathway (ko04910);; Prolactin signaling pathway (ko04917);; Type II diabetes mellitus (ko04930)	[T]	Signal transduction mechanisms	Suppressor of cytokine signalling;; SOCS box;; SH2 domain	Suppressor of cytokine signaling 4 GN=SOCS4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: suppressor of cytokine signaling 4 [Dasypus novemcinctus]
ENSG00000180011(ZADH2)	--	7.142952658	455	10.09176737	460	7.289014378	438	6.20303635	480	8.421866514	448	6.097631825	475	0.970118141	0.046183758	normal	0.968483972	-0.059363918	normal	0.965338355	0.108345896	normal	0.936829916	0.031024835	normal	[R]	General function prediction only	Biological Process: oxidation-reduction process (GO:0055114);; 	K07119|0|hsa:284273|ZADH2; zinc binding alcohol dehydrogenase domain containing 2; K07119 (A)	--	[R]	General function prediction only	Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase	Zinc-binding alcohol dehydrogenase domain-containing protein 2 GN=ZADH2 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: zinc-binding alcohol dehydrogenase domain-containing protein 2 [Ceratotherium simum simum]
ENSG00000180035(ZNF48)	--	7.93821358	536	9.27555248	621	8.628691422	603	6.102738837	427	7.368401415	494	8.035913002	529	0.81883629	-0.357677575	normal	0.831396909	-0.350549316	normal	0.950433668	-0.196654751	normal	0.150817579	-0.300001624	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Double zinc ribbon;; Drought induced 19 protein (Di19), zinc-binding;; Prokaryotic RING finger family 1;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 48 GN=ZNF48 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 48 [Bubalus bubalis]
ENSG00000180043(FAM71E2)	--	0	0	0	0	0	0	0.0295663	2	0.0284578	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF3699)	Putative protein FAM71E2 GN=FAM71E2 OS=Homo sapiens (Human) PE=5 SV=3	S	Function unknown	PREDICTED: putative protein FAM71E2 [Galeopterus variegatus]
ENSG00000180044(C3orf80)	--	0.403902	15	0.518249	20	0.30653	11	1.12631	43	2.19664	82	1.73976	66	0.201337732	1.400467878	normal	1.13E-05	1.936348152	up	1.34E-06	2.424107006	up	0.00013883	2.033173661	up	--	--	--	--	--	--	--	--	Uncharacterized membrane protein C3orf80 (Precursor) GN=C3orf80 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized membrane protein C3orf80 homolog [Orycteropus afer afer]
ENSG00000180061(TMEM150B)	--	0	0	0	0	0	0	0.086027912	1	0.0825039	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Frag1/DRAM/Sfk1 family	Transmembrane protein 150B (Precursor) GN=TMEM150B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 150B [Ceratotherium simum simum]
ENSG00000180071(ANKRD18A)	--	4.971341072	505	4.59905994	500	4.54001199	484	4.181019588	459	4.921254617	536	4.56664	498	0.955976761	-0.168084807	normal	0.968592087	0.078648574	normal	0.971187687	0.032746381	normal	0.968311023	-0.017081825	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	CCDC144C protein coiled-coil region;; Domain of unknown function (DUF3496);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 18A GN=ANKRD18A OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like [Trichechus manatus latirostris]
ENSG00000180089(TMEM86B)	--	3.35278	81	3.49038	86	2.53962	63	3.44136	83	4.63493	112	3.72109	91	0.973147162	0.004277023	normal	0.924426121	0.354192267	normal	0.86947299	0.511944529	normal	0.570902998	0.293091458	normal	[S]	Function unknown	Cellular Component: integral component of membrane (GO:0016021);; 	K18575|1.3379e-142|hsa:255043|TMEM86B; transmembrane protein 86B (EC:3.3.2.2 3.3.2.5); K18575 alkenylglycerophosphocholine/alkenylglycerophosphoethanolamine hydrolase [EC:3.3.2.2 3.3.2.5] (A)	Ether lipid metabolism (ko00565)	[R]	General function prediction only	YhhN-like protein	Lysoplasmalogenase GN=TMEM86B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: lysoplasmalogenase [Galeopterus variegatus]
ENSG00000180096(SEPT1)	--	2.40519	83	2.01508	71	1.97141	70	1.05988	37	1.4644	50	1.66222	58	0.03491982	-1.163286799	normal	0.90241715	-0.514197491	normal	0.963132781	-0.273102	normal	0.174859629	-0.647411757	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	"K13737|0|hsa:1731|SEPT1, DIFF6, LARP, PNUTL3, SEP1; septin 1 (EC:3.1.5.1); K13737 septin 1 (A)"	Bacterial invasion of epithelial cells (ko05100)	[DZU]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	"Septin;; 50S ribosome-binding GTPase;; Protein of unknown function, DUF258;; Elongation factor Tu GTP binding domain"	Septin-1 GN=SEPT1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: septin-1 isoform X1 [Pteropus alecto]
ENSG00000180098(TRNAU1AP)	--	5.753775	177	5.801425487	169	6.541213307	209	5.532684007	168	4.850194	151	5.202694	162	0.963370114	-0.105183039	normal	0.953482712	-0.182175537	normal	0.864344437	-0.372728706	normal	0.555432618	-0.227435888	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	tRNA selenocysteine 1-associated protein 1 GN=TRNAU1AP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tRNA selenocysteine 1-associated protein 1 isoform X1 [Leptonychotes weddellii]
ENSG00000180104(EXOC3)	--	17.80012001	1085	18.22496337	1109	16.60918053	1029	14.68169028	896	18.22760992	1097	17.51550178	992	0.895022239	-0.306478205	normal	0.979747559	-0.037071569	normal	0.978332708	-0.061031039	normal	0.548645989	-0.131604496	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: exocytosis (GO:0006887);; 	"K06110|0|hsa:11336|EXOC3, SEC6, SEC6L1, Sec6p; exocyst complex component 3; K06110 exocyst complex component 3 (A)"	Tight junction (ko04530)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec6	Exocyst complex component 3 GN=EXOC3 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 3 [Galeopterus variegatus]
ENSG00000180113(TDRD6)	--	0.184806295	10	0.006505854	1	0.045780237	6	0.036551147	5	0.038312342	5	0.031754013	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18405|0|hsa:221400|TDRD6, CT41.2, NY-CO-45, SPATA36, TDR2, bA446F17.4; tudor domain containing 6; K18405 tudor domain-containing protein 1/4/6/7 (A)"	--	[K]	Transcription	Tudor domain;; Domain of unknown function (DUF4537)	Tudor domain-containing protein 6 GN=TDRD6 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: tudor domain-containing protein 6 isoform 1 [Odobenus rosmarus divergens]
ENSG00000180155(LYNX1)	--	4.471648597	381	4.904108316	437	4.564183486	399	3.068342789	221	3.383427679	265	3.896685213	294	0.004618686	-0.812219395	normal	0.015603426	-0.739744036	normal	0.645119369	-0.446882956	normal	0.0015294	-0.662168804	normal	--	--	--	--	--	--	--	u-PAR/Ly-6 domain	Ly-6/neurotoxin-like protein 1 (Precursor) GN=LYNX1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: ly-6/neurotoxin-like protein 1-like isoform X1 [Leptonychotes weddellii] 
ENSG00000180182(MED14)	--	18.166819	2026	18.91472683	1957	20.19889478	2149	18.102557	1968	17.77387045	1974	16.5752858	1819	0.985433253	-0.072680289	normal	0.986348935	-0.008941444	normal	0.956452064	-0.248620979	normal	0.606419473	-0.111294251	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Cellular Component: mediator complex (GO:0016592);; 	"K15156|0|hsa:9282|MED14, CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, RGR1, TRAP170; mediator complex subunit 14; K15156 mediator of RNA polymerase II transcription subunit 14 (A)"	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	Mediator complex subunit MED14	Mediator of RNA polymerase II transcription subunit 14 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 14 [Ceratotherium simum simum]
ENSG00000180185(FAHD1)	--	26.481202	637	26.335669	761	31.824099	701	30.227479	761	27.81395091	677	31.96457702	762	0.942903663	0.225273206	normal	0.955299596	-0.189767076	normal	0.970328165	0.111853609	normal	0.880693386	0.046531524	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01557|0|hsa:81889|FAHD1, C16orf36, YISKL; fumarylacetoacetate hydrolase domain containing 1 (EC:3.7.1.5); K01557 acylpyruvate hydrolase [EC:3.7.1.5] (A)"	Tyrosine metabolism (ko00350)	[R]	General function prediction only	Fumarylacetoacetate (FAA) hydrolase family	"Acylpyruvase FAHD1, mitochondrial (Precursor) GN=FAHD1 OS=Homo sapiens (Human) PE=1 SV=2"	R	General function prediction only	"PREDICTED: acylpyruvase FAHD1, mitochondrial [Vicugna pacos]"
ENSG00000180190(TDRP)	--	15.39728256	884	14.222496	797	14.15581	807	13.0511	746	13.027067	741	9.742047	511	0.917809541	-0.275181587	normal	0.968652991	-0.126284156	normal	0.021908997	-0.665954559	normal	0.11171961	-0.338659165	normal	--	--	Biological Process: spermatogenesis (GO:0007283);; 	--	--	--	--	--	Testis development-related protein GN=TDRP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: testis development-related protein [Orycteropus afer afer]
ENSG00000180198(RCC1)	--	34.63645104	2242	37.18661198	2442	35.48302628	2374	47.71422802	2843	45.11094545	2628	41.1925832	2423	0.926385449	0.311605561	normal	0.986929592	0.084425113	normal	0.98837285	0.021169679	normal	0.490810223	0.139830283	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	--	"K11493|0|hsa:1104|RCC1, CHC1, RCC1-I, SNHG3-RCC1; regulator of chromosome condensation 1; K11493 regulator of chromosome condensation (A)"	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat	Regulator of chromosome condensation GN=RCC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: regulator of chromosome condensation-like isoform X1 [Vicugna pacos]
ENSG00000180210(F2)	--	0.059100379	1	0	0	0.046444439	1	0.442453398	13	0.67497066	24	0.408818963	17	--	--	--	0.000350324	4.066346934	up	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: proteolysis (GO:0006508);; Biological Process: blood coagulation (GO:0007596);; 	"K01313|0|hsa:2147|F2, PT, RPRGL2, THPH1; coagulation factor II (thrombin) (EC:3.4.21.5); K01313 coagulation factor II (thrombin) [EC:3.4.21.5] (A)"	Neuroactive ligand-receptor interaction (ko04080);; Complement and coagulation cascades (ko04610);; Regulation of actin cytoskeleton (ko04810)	--	--	Trypsin;; Kringle domain;; Thrombin light chain;; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain	Thrombin heavy chain (Precursor) GN=F2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: prothrombin [Felis catus]
ENSG00000180228(PRKRA)	--	17.453587	506	18.91950112	557	18.392738	525	14.80533	436	15.218863	435	11.8610154	346	0.929290985	-0.244839676	normal	0.787498454	-0.376927189	normal	0.108404991	-0.607664702	normal	0.04597151	-0.405732553	normal	--	--	--	--	--	[UK]	"Intracellular trafficking, secretion, and vesicular transport;; Transcription"	Double-stranded RNA binding motif;; double strand RNA binding domain from DEAD END PROTEIN 1	Interferon-inducible double-stranded RNA-dependent protein kinase activator A GN=PRKRA OS=Homo sapiens (Human) PE=1 SV=1	KU	"Transcription;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: interferon-inducible double stranded RNA-dependent protein kinase activator A [Canis lupus familiaris] 
ENSG00000180233(ZNRF2)	--	8.864384558	541	8.754730714	576	8.3336574	518	7.900510646	555	8.26188141	544	9.047341192	593	0.972660593	0.006010062	normal	0.967244232	-0.103608754	normal	0.953189199	0.186279927	normal	0.940283296	0.028287287	normal	--	--	--	"K10694|2.96489e-94|hsa:223082|ZNRF2, RNF202; zinc and ring finger 2, E3 ubiquitin protein ligase; K10694 E3 ubiquitin-protein ligase ZNRF1/2 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ring finger domain	E3 ubiquitin-protein ligase ZNRF2 GN=ZNRF2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	E3 ubiquitin-protein ligase ZNRF2 [Bos taurus] 
ENSG00000180245(RRH)	--	0.0500125	1	0	0	0	0	0.0995192	2	0.0487714	0	0.0992481	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04253|0|ptr:736907|RRH; retinal pigment epithelium-derived rhodopsin homolog; K04253 visual pigment-like receptor peropsin (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Visual pigment-like receptor peropsin GN=RRH OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: visual pigment-like receptor peropsin [Galeopterus variegatus]
ENSG00000180251(SLC9A4)	--	0.0686494	5	0.0685943	5	0.0136487	0	0.109143	8	0.0931158	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13961|0|hsa:389015|SLC9A4, NHE4; solute carrier family 9, subfamily A (NHE4, cation proton antiporter 4), member 4; K13961 solute carrier family 9 (sodium/hydrogen exchanger), member 4 (A)"	Gastric acid secretion (ko04971)	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 4 GN=SLC9A4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 4 [Canis lupus familiaris]
ENSG00000180257(ZNF816)	--	0.336475414	12	0.521267237	13	0.543478407	22	0.242827829	12	0.103979574	4	0.374715284	17	--	--	--	--	--	--	0.985398239	-0.352617853	normal	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:125893|ZNF816, ZNF816A; zinc finger protein 816; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger of C2H2 type;; BolA-like protein;; Bacterial dnaA protein helix-turn-helix"	Zinc finger protein 816 GN=ZNF816 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 347-like [Galeopterus variegatus]
ENSG00000180263(FGD6)	--	15.074039	2234	16.8513441	2429	16.47303315	2417	16.2431247	2310	15.56325188	2359	19.2803622	2884	0.987941345	0.017419621	normal	0.987179937	-0.063573463	normal	0.964255863	0.24642093	normal	0.763770602	0.072812783	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Molecular Function: metal ion binding (GO:0046872);; 	"K05724|0|hsa:55785|FGD6, ZFYVE24; FYVE, RhoGEF and PH domain containing 6; K05724 FYVE, RhoGEF and PH domain containing 5/6 (A)"	--	[R]	General function prediction only	RhoGEF domain;; FYVE zinc finger;; PH domain;; Pleckstrin homology domain	"FYVE, RhoGEF and PH domain-containing protein 6 GN=FGD6 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: FYVE, RhoGEF and PH domain-containing protein 6 [Ceratotherium simum simum]"
ENSG00000180264(ADGRD2)	--	0.0944068	5	0.200832	11	0.035767	1	0.0187849	1	0.0550291	2	0.0373987	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08466|0|hsa:347088|GPR144, PGR24, ADGRD2; G protein-coupled receptor 144; K08466 G protein-coupled receptor 144 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Pentaxin family;; Concanavalin A-like lectin/glucanases superfamily;; Latrophilin/CL-1-like GPS domain	Probable G-protein coupled receptor 144 GN=GPR144 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 144 isoform X1 [Bos taurus]
ENSG00000180287(PLD5)	--	10.47401321	357	12.38122	371	9.143608149	323	4.132551762	137	6.178428351	210	7.44492336	249	3.04E-09	-1.402449234	down	0.003549443	-0.837852999	normal	0.812299354	-0.381638832	normal	0.000189349	-0.838016726	normal	--	--	--	"K16861|0|mcf:102146079|PLD5; phospholipase D family, member 5; K16861 inactive phospholipase D5 (A)"	--	[R]	General function prediction only	PLD-like domain;; PLD-like domain;; Phospholipase D Active site motif	Inactive phospholipase D5 GN=PLD5 OS=Homo sapiens (Human) PE=2 SV=2	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: inactive phospholipase D5-like [Orcinus orca]
ENSG00000180304(OAZ2)	--	53.19265975	1515	46.072646	1360	52.63032386	1543	53.89789708	1575	55.45289682	1606	41.10808298	1187	0.984158791	0.02517673	normal	0.960706931	0.218215182	normal	0.7714149	-0.386276637	normal	0.903805973	-0.038192352	normal	--	--	Molecular Function: ornithine decarboxylase inhibitor activity (GO:0008073);; 	K16613|3.97272e-119|tup:102472904|OAZ2; ornithine decarboxylase antizyme 2; K16613 ornithine decarboxylase antizyme 2 (A)	--	[E]	Amino acid transport and metabolism	Ornithine decarboxylase antizyme	Ornithine decarboxylase antizyme 2 GN=OAZ2 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	ornithine decarboxylase antizyme 2 [Elephantulus edwardii] 
ENSG00000180316(PNPLA1)	--	0	0	0.021655379	1	0	0	0	0	0.021166299	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	K16813|0|pps:100981874|PNPLA1; patatin-like phospholipase domain containing 1; K16813 patatin-like phospholipase domain-containing protein 1 [EC:3.1.1.-] (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Patatin-like phospholipase	Patatin-like phospholipase domain-containing protein 1 GN=PNPLA1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: patatin-like phospholipase domain-containing protein 1 [Leptonychotes weddellii]
ENSG00000180318(ALX1)	--	4.795535849	107	4.518648515	105	3.506545119	77	4.844052257	106	6.974256475	157	5.243547291	127	0.969980524	-0.043747651	normal	0.658516263	0.552402557	normal	0.41822175	0.702753133	normal	0.30908062	0.41133427	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	"K09334|0|ptr:452109|ALX1, CART1; ALX homeobox 1; K09334 cartilage homeoprotein 1 (A)"	--	[R]	General function prediction only	Homeobox domain;; OAR domain;; Homeobox KN domain	ALX homeobox protein 1 GN=ALX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ALX homeobox protein 1 [Elephantulus edwardii]
ENSG00000180329(CCDC43)	--	18.005844	699	19.001688	757	17.364361	681	18.386986	735	17.717024	687	19.313798	752	0.974945776	0.041530508	normal	0.962079307	-0.161071817	normal	0.967123646	0.134502082	normal	0.996314771	0.003478177	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 43 GN=CCDC43 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 43 [Eptesicus fuscus]
ENSG00000180332(KCTD4)	--	0.0336334	1	0.238013	7	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD4 GN=KCTD4 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD4 [Dasypus novemcinctus]
ENSG00000180336(MEIOC)	--	8.335262199	617	6.637880182	494	8.958749607	577	6.45411601	345	4.867677827	326	3.113652099	234	0.000311565	-0.866577074	normal	0.106030521	-0.61871619	normal	1.08E-09	-1.30479925	down	7.34E-07	-0.921459979	normal	--	--	Biological Process: meiotic cell cycle (GO:0051321);; 	--	--	--	--	Domain of unknown function (DUF4582)	Uncharacterized protein C17orf104 GN=C17orf104 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C17orf104 homolog [Leptonychotes weddellii]
ENSG00000180340(FZD2)	--	60.203	2410	56.3212	2517	59.1002	2477	59.7498	2592	72.0127	3026	69.0278	2993	0.987519223	0.074154719	normal	0.966267656	0.244146272	normal	0.958036728	0.264559822	normal	0.282258046	0.197159298	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	K02235|0|bacu:102998345|FZD2; frizzled class receptor 2; K02235 frizzled 2 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain	Frizzled-2 (Precursor) GN=FZD2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: frizzled-2 [Camelus dromedarius]
ENSG00000180346(TIGD2)	--	3.691832652	204	3.839425063	211	4.25526056	232	7.226329597	402	5.922319305	328	6.934362882	385	0.000254576	0.942646298	normal	0.206188516	0.611484845	normal	0.028261117	0.718767437	normal	0.000342344	0.763990538	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; Tc5 transposase DNA-binding domain;; CENP-B N-terminal DNA-binding domain	Tigger transposable element-derived protein 2 GN=TIGD2 OS=Homo sapiens (Human) PE=2 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: tigger transposable element-derived protein 2 [Camelus ferus] 
ENSG00000180353(HCLS1)	--	0	0	0	0	0.0419501	1	0.02732131	1	0.064250435	2	0.02758049	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K06106|0|ptr:460623|HCLS1; hematopoietic cell-specific Lyn substrate 1; K06106 cortactin (A)	Tight junction (ko04530);; Bacterial invasion of epithelial cells (ko05100);; Proteoglycans in cancer (ko05205)	--	--	Repeat in HS1/Cortactin;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Hematopoietic lineage cell-specific protein GN=HCLS1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: hematopoietic lineage cell-specific protein [Equus caballus]
ENSG00000180354(MTURN)	--	3.719236073	238	1.648958849	132	2.81759477	205	2.304366344	226	2.687335564	198	2.723439313	178	0.962445382	-0.104776808	normal	0.549134237	0.558281065	normal	0.946990998	-0.210371183	normal	0.946734065	0.044578811	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4581)	Maturin GN=MTURN OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: UPF0452 protein C7orf41 homolog [Ceratotherium simum simum]
ENSG00000180357(ZNF609)	--	15.7084042	3153	17.491679	3522	16.896776	3376	16.025795	3186	17.7187673	3520	14.895994	2982	0.990588098	-0.015803506	normal	0.990997399	-0.022236488	normal	0.980999218	-0.187236784	normal	0.756831658	-0.074381227	normal	--	--	--	--	--	--	--	--	Zinc finger protein 609 GN=ZNF609 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 609 [Condylura cristata]
ENSG00000180376(CCDC66)	--	2.010635	141	2.743948031	192	2.24457	154	2.34885	168	2.176000004	155	2.56017	183	0.948635433	0.219738157	normal	0.902237518	-0.327388569	normal	0.942155856	0.238471169	normal	0.958358569	0.034038545	normal	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 66	Coiled-coil domain-containing protein 66 GN=CCDC66 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 66 isoform X1 [Equus caballus]
ENSG00000180398(MCFD2)	--	68.23420807	4711	67.961215	4208	69.101182	4584	77.30025325	5258	70.33053571	4737	60.64877637	4021	0.990768772	0.127609141	normal	0.98840704	0.149361796	normal	0.98350784	-0.197274607	normal	0.90801502	0.031884257	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[S]	Function unknown	EF-hand domain pair;; EF-hand domain;; EF hand	Multiple coagulation factor deficiency protein 2 (Precursor) GN=MCFD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: multiple coagulation factor deficiency protein 2 [Galeopterus variegatus] 
ENSG00000180423(HARBI1)	--	4.152619	162	3.930591	177	4.160413	145	3.242861	147	3.578203	159	4.272629	184	0.957402994	-0.169323169	normal	0.95412499	-0.174574504	normal	0.904347784	0.332278227	normal	1	-0.003028914	normal	--	--	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	--	--	[L]	"Replication, recombination and repair"	DDE superfamily endonuclease;; Plant transposon protein	Putative nuclease HARBI1 GN=HARBI1 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: putative nuclease HARBI1 [Camelus dromedarius]
ENSG00000180425(C11orf71)	--	2.26733	55	3.27271	80	1.46999	35	1.21568	30	1.98098	48	2.23675	55	0.68831985	-0.871822822	normal	0.637031537	-0.740131524	normal	0.899663674	0.62217373	normal	0.638526769	-0.374627944	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf71 GN=C11orf71 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C11orf71 homolog [Dasypus novemcinctus]
ENSG00000180447(GAS1)	--	0.0267321	1	0	0	0	0	0.0524553	2	0	0	0.0262021	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06232|9.24947e-128|cjc:100387787|GAS1; growth arrest-specific 1; K06232 growth arrest-specific 1 (A)	Hedgehog signaling pathway (ko04340)	--	--	GDNF/GAS1 domain	Growth arrest-specific protein 1 (Precursor) GN=GAS1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: growth arrest-specific protein 1 [Orcinus orca]
ENSG00000180448(ARHGAP45)	--	2.162234579	145	1.950193458	131	1.635638524	120	2.911702956	201	3.082487066	225	2.746642802	171	0.797429907	0.436368241	normal	0.073490775	0.752230392	normal	0.734953553	0.497393408	normal	0.058951648	0.570461033	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	"RhoGAP domain;; Fes/CIP4, and EFC/F-BAR homology domain"	Minor histocompatibility antigen HA-1 GN=HMHA1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: minor histocompatibility protein HA-1 isoform X2 [Galeopterus variegatus]
ENSG00000180479(ZNF571)	--	0.478604668	23	1.092574	46	0.730923493	28	0.54276271	25	0.692481122	27	0.9999126	47	0.987235526	0.084074398	normal	0.864736198	-0.757234241	normal	0.891350282	0.709084679	normal	1	0.009650261	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:51276|ZNF571; zinc finger protein 571; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; NTF2 fold immunity protein;; Transposase zinc-ribbon domain;; Probable zinc-binding domain"	Zinc finger protein 571 GN=ZNF571 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 571 [Leptonychotes weddellii]
ENSG00000180481(GLIPR1L2)	--	0.52551605	10	0.189366856	6	0.534834534	15	0.209588177	6	0.313002654	4	0.231892142	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Cysteine-rich secretory protein family	GLIPR1-like protein 2 GN=GLIPR1L2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: GLIPR1-like protein 2, partial [Tupaia chinensis]"
ENSG00000180488(MIGA1)	--	6.106471498	546	6.036928878	548	6.877883213	613	6.47673911	626	5.642812539	491	6.870458591	622	0.95859802	0.165992979	normal	0.953549401	-0.179356202	normal	0.974007984	0.012704948	normal	0.991031416	0.005681881	normal	--	--	Biological Process: mitochondrial fusion (GO:0008053);; 	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2217)	Protein FAM73A GN=FAM73A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM73A [Tupaia chinensis]
ENSG00000180509(KCNE1)	--	0.083215051	1	0	0	0.015549421	0	0	0	0	0	0.108603276	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: voltage-gated potassium channel activity (GO:0005249);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	"K04894|1.28973e-92|hsa:3753|KCNE1, ISK, JLNS, JLNS2, LQT2/5, LQT5, MinK; potassium voltage-gated channel, Isk-related family, member 1; K04894 potassium voltage-gated channel Isk-related subfamily E member 1 (A)"	Adrenergic signaling in cardiomyocytes (ko04261)	--	--	Slow voltage-gated potassium channel	Potassium voltage-gated channel subfamily E member 1 GN=KCNE1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily E member 1 [Ursus maritimus]
ENSG00000180525(PRR26)	--	0.065346614	4	0.194805946	8	0.084909164	3	0.6177469	38	0.862077	56	0.5010451	36	0.000173373	2.81019469	up	4.55E-06	2.576564977	up	8.69E-05	3.048697815	up	1.43E-07	3.093128703	up	--	--	--	--	--	--	--	--	Proline-rich protein 26 GN=PRR26 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000180530(NRIP1)	--	21.012	2878	19.57005	2645	18.75898	2498	18.456521	2520	18.473083	2405	15.20562	2080	0.97169476	-0.222348146	normal	0.981455518	-0.158562266	normal	0.949357462	-0.272300466	normal	0.222832775	-0.217293204	normal	--	--	--	"K17965|0|hsa:8204|NRIP1, RIP140; nuclear receptor interacting protein 1; K17965 nuclear receptor-interacting protein 1 (A)"	--	--	--	--	Nuclear receptor-interacting protein 1 GN=NRIP1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor-interacting protein 1-like [Tupaia chinensis] 
ENSG00000180535(BHLHA15)	--	0.472092158	5	0.360455688	4	0.305155574	2	0.456364901	5	0.105963147	0	0.734535349	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K08040|7.16238e-97|ptr:472455|BHLHA15, BHLHB8; basic helix-loop-helix family, member a15; K08040 class B basic helix-loop-helix protein 8 (A)"	Maturity onset diabetes of the young (ko04950)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Class A basic helix-loop-helix protein 15 GN=BHLHA15 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: class A basic helix-loop-helix protein 15 [Condylura cristata]
ENSG00000180537(RNF182)	--	6.326734563	342	6.170701937	267	6.82154579	332	7.507658511	299	4.367378827	224	3.984896689	194	0.938136448	-0.223607692	normal	0.919193519	-0.273076442	normal	0.013921856	-0.778721208	normal	0.135600094	-0.414588983	normal	--	--	--	K11983|3.91694e-138|ptr:471860|RNF182; ring finger protein 182; K11983 E3 ubiquitin-protein ligase RNF182 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	E3 ubiquitin-protein ligase RNF182 GN=RNF182 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF182 [Odobenus rosmarus divergens]
ENSG00000180543(TSPYL5)	--	14.102	1051	14.0015	1061	13.225	991	12.9911	974	14.3022	1059	11.3001	844	0.971076787	-0.140387989	normal	0.97956318	-0.024114222	normal	0.941893268	-0.239536952	normal	0.557156575	-0.130733926	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11288|0|hsa:85453|TSPYL5; TSPY-like 5; K11288 TSPY-like 5 (A)	--	[L]	"Replication, recombination and repair"	Nucleosome assembly protein (NAP)	Testis-specific Y-encoded-like protein 5 GN=TSPYL5 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: testis-specific Y-encoded-like protein 5 isoform X1 [Mustela putorius furo] 
ENSG00000180549(FUT7)	--	0.0444364	2	0.105892	5	0.06243	2	0	0	0.0216672	0	0.0218158	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: fucosyltransferase activity (GO:0008417);; Cellular Component: membrane (GO:0016020);; 	"K07635|0|hsa:2529|FUT7, FucT-VII; fucosyltransferase 7 (alpha (1,3) fucosyltransferase) (EC:2.4.1.-); K07635 galactoside alpha-1,3-fucosyltransferase 7 [EC:2.4.1.-] (A)"	Other types of O-glycan biosynthesis (ko00514);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Glycosyltransferase family 10 (fucosyltransferase)	"Alpha-(1,3)-fucosyltransferase 7 GN=FUT7 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-(1,3)-fucosyltransferase-like [Ceratotherium simum simum]"
ENSG00000180573(HIST1H2AC)	--	26.07183	592	26.87837	608	28.66514	641	20.01164	461	19.92581	447	29.49571	670	0.75009413	-0.390510699	normal	0.539047483	-0.463871648	normal	0.973423994	0.055417406	normal	0.417072694	-0.242361358	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.13362e-70|ptr:462490|HIST1H2AC; histone H2A type 1-C; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1-C GN=HIST1H2AC OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 1-E-like [Leptonychotes weddellii]
ENSG00000180592(SKIDA1)	--	1.357464081	132	1.776837324	148	1.723291004	150	0.665676029	57	0.82859436	74	0.690173	69	0.00089972	-1.220076325	down	0.010206394	-1.006584361	normal	0.00201639	-1.111649349	down	0.000588405	-1.124787821	down	--	--	--	--	--	--	--	Domain of unknown function (DUF4584);; SKI/SNO/DAC family	SKI/DACH domain-containing protein 1 GN=SKIDA1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SKI/DACH domain-containing protein 1 [Sus scrofa]
ENSG00000180596(HIST1H2BC)	--	2.986620902	56	2.129042	47	3.019557	46	3.14742415	45	2.296772	40	2.393775404	54	0.96410548	-0.336026533	normal	0.973470447	-0.245514095	normal	0.973546056	0.216459925	normal	0.890265455	-0.121080763	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|5.83049e-60|lve:103082925|histone H2B type 1-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-N GN=HIST1H2BN OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5-like [Bubalus bubalis]
ENSG00000180611(MB21D2)	--	2.30889	113	2.3883039	129	2.0894052	111	3.689537442	185	3.743642	186	2.879048	148	0.273639761	0.673152145	normal	0.703442591	0.50158347	normal	0.876940209	0.401987699	normal	0.104529234	0.534103647	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Mab-21 protein	Protein MB21D2 GN=MB21D2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein MB21D2 [Loxodonta africana] 
ENSG00000180616(SSTR2)	--	0.0738615	11	0.0732021	11	0.0530158	7	0.0601575	9	0.0586861	8	0.0597926	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04218|0|ptr:454854|SSTR2; somatostatin receptor 2; K04218 somatostatin receptor 2 (A)	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Gastric acid secretion (ko04971)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srx	Somatostatin receptor type 2 GN=SSTR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: somatostatin receptor type 2 [Trichechus manatus latirostris]
ENSG00000180626(ZNF594)	--	2.36065658	260	1.781105706	198	1.767745224	184	1.6768582	161	2.416200705	174	2.77619386	159	0.072640683	-0.716844616	normal	0.946891496	-0.206158608	normal	0.947169871	-0.217049591	normal	0.197709848	-0.399557099	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 594 GN=ZNF594 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 594 [Orcinus orca]
ENSG00000180628(PCGF5)	--	12.7201	1275	13.46474044	1332	13.43780348	1304	14.59777034	1478	11.26302324	1131	13.386506	1347	0.968602765	0.182112802	normal	0.940371294	-0.257104518	normal	0.982284595	0.03847064	normal	0.990286694	-0.005098017	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K11489|4.9941e-169|pon:100460419|PCGF5; polycomb group ring finger 5; K11489 polycomb group RING finger protein 5 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[S]	Function unknown	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	Polycomb group RING finger protein 5 GN=PCGF5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polycomb group RING finger protein 5 [Condylura cristata]
ENSG00000180638(SLC47A2)	--	0.095919912	3	0.07996076	3	0.105521181	3	0.0272639	1	0.08019487	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Biological Process: drug transmembrane transport (GO:0006855);; Molecular Function: drug transmembrane transporter activity (GO:0015238);; Molecular Function: antiporter activity (GO:0015297);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K03327|0|hsa:146802|SLC47A2, MATE2, MATE2-B, MATE2-K, MATE2K; solute carrier family 47 (multidrug and toxin extrusion), member 2; K03327 multidrug resistance protein, MATE family (A)"	--	[R]	General function prediction only	MatE	Multidrug and toxin extrusion protein 2 GN=SLC47A2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: multidrug and toxin extrusion protein 2 [Odobenus rosmarus divergens]
ENSG00000180660(MAB21L1)	--	0.0181294	1	0	0	0.0177974	0	0	0	0	0	0.0357236	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Mab-21 protein	Protein mab-21-like 1 GN=MAB21L1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protein mab-21-like 1 [Ceratotherium simum simum]
ENSG00000180667(YOD1)	--	3.988604	355	4.365145219	386	4.889436838	424	8.027759	723	6.053280581	539	6.671742453	595	6.76E-06	0.992275494	normal	0.573950147	0.45873058	normal	0.474274654	0.479084864	normal	0.000569898	0.650960601	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K13719|0|pps:100986255|YOD1; YOD1 deubiquitinase; K13719 ubiquitin thioesterase OTU1 [EC:3.1.2.-] (A)	Protein processing in endoplasmic reticulum (ko04141)	[TO]	"Signal transduction mechanisms;; Posttranslational modification, protein turnover, chaperones"	OTU-like cysteine protease	Ubiquitin thioesterase OTU1 GN=YOD1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin thioesterase OTU1 [Galeopterus variegatus]
ENSG00000180694(TMEM64)	--	16.56459711	857	19.85381661	1042	17.96262316	950	17.78941582	949	17.50792952	941	14.8143098	791	0.972540869	0.116082802	normal	0.965661796	-0.168258099	normal	0.921866133	-0.272065925	normal	0.644620054	-0.109409677	normal	--	--	--	--	--	[S]	Function unknown	SNARE associated Golgi protein	Transmembrane protein 64 GN=TMEM64 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 64-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000180720(CHRM4)	--	0.0825164	2	0.289953	7	0	0	0.0826481	2	0.0796683	1	0.0406901	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04132|0|pps:100979240|CHRM4; cholinergic receptor, muscarinic 4; K04132 muscarinic acetylcholine receptor M4 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Muscarinic acetylcholine receptor M4 GN=CHRM4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: muscarinic acetylcholine receptor M4 [Tupaia chinensis] 
ENSG00000180739(S1PR5)	--	4.255140041	158	4.061203014	151	4.753193442	181	3.350885013	125	4.075094536	150	1.383176379	45	0.894800465	-0.364829602	normal	0.966261613	-0.03070408	normal	2.76E-11	-1.980432075	down	0.207422968	-0.637584763	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04295|0|hsa:53637|S1PR5, EDG8, Edg-8, S1P5, SPPR-1, SPPR-2; sphingosine-1-phosphate receptor 5; K04295 sphingosine 1-phosphate receptor 5 (A)"	Sphingolipid signaling pathway (ko04071);; Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family)	Sphingosine 1-phosphate receptor 5 GN=S1PR5 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: sphingosine 1-phosphate receptor 5 isoform X1 [Canis lupus familiaris] 
ENSG00000180745(CLRN3)	--	0	0	0	0	0	0	0	0	0	0	0.0654141	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PMP-22/EMP/MP20/Claudin tight junction	Clarin-3 GN=CLRN3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: clarin-3 [Galeopterus variegatus]
ENSG00000180758(GPR157)	--	3.365688699	316	3.128226444	297	2.974953262	283	2.1623149	203	2.816683222	264	21.7968913	282	0.098442046	-0.66520604	normal	0.947499889	-0.190322953	normal	0.967533555	-0.01332699	normal	0.322929403	-0.278835695	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	K08467|0|hsa:80045|GPR157; G protein-coupled receptor 157; K08467 G protein-coupled receptor 157 (A)	--	--	--	7 transmembrane receptor (Secretin family);; Slime mold cyclic AMP receptor;; 7 transmembrane receptor (rhodopsin family);; Frizzled/Smoothened family membrane region	Probable G-protein coupled receptor 157 GN=GPR157 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	"PREDICTED: probable G-protein coupled receptor 157, partial [Mustela putorius furo]"
ENSG00000180767(CHST13)	--	1.608720692	36	1.590481454	37	1.404453848	33	0.441737	8	1.060442	20	1.034129948	24	0.018076497	-2.004484189	normal	0.871517883	-0.860410694	normal	0.973241038	-0.44378187	normal	0.081997098	-1.045916149	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	"K07779|0|hsa:166012|CHST13, C4ST3; carbohydrate (chondroitin 4) sulfotransferase 13 (EC:2.8.2.5); K07779 chondroitin 4-sulfotransferase 13 [EC:2.8.2.5] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[MW]	Cell wall/membrane/envelope biogenesis;; Extracellular structures	Sulfotransferase family	Carbohydrate sulfotransferase 13 GN=CHST13 OS=Homo sapiens (Human) PE=2 SV=1	MW	Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: carbohydrate sulfotransferase 13 [Odobenus rosmarus divergens]
ENSG00000180772(AGTR2)	--	0.0294188	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04167|0|hsa:186|AGTR2, AT2, ATGR2, MRX88; angiotensin II receptor, type 2; K04167 angiotensin II receptor type 2 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Adrenergic signaling in cardiomyocytes (ko04261);; Renin-angiotensin system (ko04614)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Type-2 angiotensin II receptor GN=AGTR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: type-2 angiotensin II receptor-like [Tupaia chinensis] 
ENSG00000180773(SLC36A4)	--	11.18760687	616	15.2196494	697	12.72446734	616	12.941212	670	12.133841	607	14.409166	738	0.970747316	0.090182772	normal	0.943740113	-0.220375838	normal	0.92979117	0.251833463	normal	0.896393976	0.041840421	normal	--	--	--	"K14209|0|ptr:466748|SLC36A4; solute carrier family 36 (proton/amino acid symporter), member 4; K14209 solute carrier family 36 (proton-coupled amino acid transporter) (A)"	--	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Proton-coupled amino acid transporter 4 GN=SLC36A4 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: proton-coupled amino acid transporter 4 [Canis lupus familiaris]
ENSG00000180776(ZDHHC20)	--	19.58729913	1544	20.03064876	1477	18.00925587	1400	20.04502735	1583	21.66448073	1490	20.19690857	1399	0.984465877	0.005151177	normal	0.983518212	-0.008775108	normal	0.983324665	-0.009312244	normal	0.990244084	-0.005139299	normal	[R]	General function prediction only	--	"K18932|0|mcf:102137570|ZDHHC20; zinc finger, DHHC-type containing 20; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC20 GN=ZDHHC20 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC20 isoformX2 [Canis lupus familiaris]
ENSG00000180777(ANKRD30B)	--	0	0	0	0	0	0	0.0477825	5	0.0373198	3	0.0191196	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 30B GN=ANKRD30B OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: ankyrin repeat domain-containing protein 26 isoform X3 [Loxodonta africana]
ENSG00000180787(ZFP3)	--	0.269904258	24	0.1343366	12	0.257586036	22	0.774978785	69	0.72013	64	0.97269277	87	0.010014136	1.436241224	normal	1.04E-05	2.257513594	up	6.93E-06	1.904508854	up	2.13E-05	1.903349604	up	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 3 homolog GN=ZFP3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 3 homolog [Balaenoptera acutorostrata scammoni]
ENSG00000180801(ARSJ)	--	5.397708795	479	5.299266427	469	6.354198259	550	6.922416573	616	5.293742064	465	3.999451167	353	0.856577917	0.331133789	normal	0.969851328	-0.033674715	normal	0.0533034	-0.645819784	normal	0.867488765	-0.085603041	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K12375|0|hsa:79642|ARSJ; arylsulfatase family, member J (EC:3.1.6.12); K12375 arylsulfatase I/J [EC:3.1.6.-] (A)"	--	[R]	General function prediction only	Sulfatase	Arylsulfatase J (Precursor) GN=ARSJ OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: arylsulfatase J [Galeopterus variegatus]
ENSG00000180806(HOXC9)	--	1.95267287	52	2.76249349	74	2.080984041	56	5.366357643	144	5.228948266	141	4.25165	116	2.88E-05	1.412559598	up	0.057407499	0.895204653	normal	0.029079426	1.022740403	normal	0.001051567	1.117597412	up	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K09294|0|ptr:735639|HOXC9; homeobox C9; K09294 homeobox protein HoxA/B/C/D9 (A)	--	[K]	Transcription	Hox9 activation region;; Homeobox domain	Homeobox protein Hox-C9 GN=HOXC9 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-C9 [Chrysochloris asiatica]
ENSG00000180815(MAP3K15)	--	2.57416	217	3.25752	276	2.56781	217	1.82989	154	1.30108	109	2.03069	171	0.599274411	-0.521192734	normal	2.06E-07	-1.349566426	down	0.881443858	-0.34924169	normal	0.005746345	-0.731408928	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K13986|0|hsa:389840|MAP3K15, ASK3, bA723P2.3; mitogen-activated protein kinase kinase kinase 15 (EC:2.7.11.25); K13986 mitogen-activated protein kinase kinase kinase 15 [EC:2.7.11.25] (A)"	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4071);; Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase 15 GN=MAP3K15 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 15 [Odobenus rosmarus divergens]
ENSG00000180817(PPA1)	--	77.549387	1652	74.710528	1616	82.99074	1745	134.874908	2931	125.43083	2574	106.6944611	2292	0.000302379	0.795784318	normal	0.022794541	0.649672499	normal	0.80102683	0.384796725	normal	1.15E-05	0.615425114	normal	[C]	Energy production and conversion	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: inorganic diphosphatase activity (GO:0004427);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: phosphate-containing compound metabolic process (GO:0006796);; 	"K01507|0|hsa:5464|PPA1, HEL-S-66p, IOPPP, PP, PP1, SID6-8061; pyrophosphatase (inorganic) 1 (EC:3.6.1.1); K01507 inorganic pyrophosphatase [EC:3.6.1.1] (A)"	Oxidative phosphorylation (ko00190)	[C]	Energy production and conversion	Inorganic pyrophosphatase	Inorganic pyrophosphatase GN=PPA1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: inorganic pyrophosphatase [Mustela putorius furo] 
ENSG00000180822(PSMG4)	--	14.7000177	182	15.4978932	229	15.9414006	241	17.2237226	223	13.936388	199	12.782307	195	0.93075488	0.260285289	normal	0.940881582	-0.22242848	normal	0.902282789	-0.311672007	normal	0.814970207	-0.100979345	normal	--	--	Biological Process: proteasome assembly (GO:0043248);; 	"K11878|5.15258e-98|mcf:102116637|PSMG4; proteasome (prosome, macropain) assembly chaperone 4; K11878 proteasome assembly chaperone 4 (A)"	--	--	--	--	Proteasome assembly chaperone 4 GN=PSMG4 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: proteasome assembly chaperone 4 [Ceratotherium simum simum]
ENSG00000180855(ZNF443)	--	2.327808705	122	2.21472402	109	2.0511621	90	2.0237939	99	1.823677933	95	1.851791035	97	0.929926086	-0.327622993	normal	0.956329279	-0.216534336	normal	0.969428812	0.098178924	normal	0.769995184	-0.163218049	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:10224|ZNF443, ZK1; zinc finger protein 443; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; NTF2 fold immunity protein"	Zinc finger protein 443 GN=ZNF443 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 709 [Oryctolagus cuniculus]
ENSG00000180875(GREM2)	--	0.495634064	37	0.520088	39	0.260443343	19	0.126985181	9	0.110428719	7	0.140780985	10	0.026674978	-1.898803119	normal	0.001943525	-2.269864974	down	--	--	--	--	--	--	--	--	--	--	--	--	--	DAN domain;; Cystine-knot domain	Gremlin-2 (Precursor) GN=GREM2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: gremlin-2 isoform X1 [Panthera tigris altaica] 
ENSG00000180878(C11orf42)	--	0.503106	9	0.222505	4	0.162602	2	0.55654	10	0.163203	2	0.274608	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf42 GN=C11orf42 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C11orf42 homolog isoform X2 [Felis catus]
ENSG00000180879(SSR4)	--	212.573323	1464	216.843993	1516	205.461937	1484	273.23535	1982	277.46465	1897	247.93766	1773	0.730197431	0.40584189	normal	0.920875739	0.30175379	normal	0.951606375	0.248178337	normal	0.047295892	0.318891469	normal	--	--	Cellular Component: endoplasmic reticulum (GO:0005783);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04571|1.02803e-107|pon:100174257|SSR4; signal sequence receptor, delta; K04571 translocon-associated protein subunit delta (A)"	Protein processing in endoplasmic reticulum (ko04141)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Translocon-associated protein, delta subunit precursor (TRAP-delta)"	Translocon-associated protein subunit delta (Precursor) GN=SSR4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: translocon-associated protein subunit delta isoform X1 [Galeopterus variegatus]
ENSG00000180881(CAPS2)	--	3.117546983	141	1.83177526	91	3.094027057	120	2.90496621	152	3.800362214	177	2.319976	114	0.966208723	0.076738454	normal	0.014700529	0.927145793	normal	0.967721899	-0.081241454	normal	0.454449733	0.310059018	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF-hand domain;; EF hand	Calcyphosin-2 GN=CAPS2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: calcyphosin-2-like [Myotis lucifugus]
ENSG00000180884(ZNF792)	--	1.533550137	119	1.33969189	106	1.3910085	110	1.4284011	110	1.55055684	121	1.67734138	132	0.964279258	-0.142377599	normal	0.960426295	0.167281274	normal	0.94749766	0.251581571	normal	0.874698386	0.095163696	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:126375|ZNF792; zinc finger protein 792; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc-finger domain"	Zinc finger protein 792 GN=ZNF792 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 792 [Galeopterus variegatus]
ENSG00000180891(CUEDC1)	--	47.654117	3820	45.35350369	3838	43.570511	3642	30.33902827	2304	38.67070451	3175	36.55261484	2906	0.000862104	-0.759866101	normal	0.951363931	-0.294896703	normal	0.916960784	-0.333832132	normal	0.002457081	-0.450955088	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	CUE domain	CUE domain-containing protein 1 GN=CUEDC1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: CUE domain-containing protein 1 [Orycteropus afer afer]
ENSG00000180901(KCTD2)	--	13.582237	940	12.49361663	876	12.99361625	908	13.866641	957	13.790853	946	12.63632022	876	0.978925212	-0.004966051	normal	0.974732862	0.089334329	normal	0.976877119	-0.059951206	normal	0.985612711	0.007418004	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD2 GN=KCTD2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: BTB/POZ domain-containing protein KCTD2 [Myotis lucifugus]
ENSG00000180902(D2HGDH)	--	15.97476191	543	14.89373762	567	15.96707697	536	10.60875578	339	13.82528066	380	11.261399	339	0.01600889	-0.707938561	normal	0.128024979	-0.596817599	normal	0.037635078	-0.66685224	normal	0.000382486	-0.65882257	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[C]	Energy production and conversion	"FAD linked oxidases, C-terminal domain;; FAD binding domain"	"D-2-hydroxyglutarate dehydrogenase, mitochondrial (Precursor) GN=D2HGDH OS=Homo sapiens (Human) PE=1 SV=3"	C	Energy production and conversion	"PREDICTED: D-2-hydroxyglutarate dehydrogenase, mitochondrial [Galeopterus variegatus]"
ENSG00000180914(OXTR)	--	2.778880137	195	4.078471125	188	3.006924695	231	6.627060407	373	4.417962033	317	2.738726	210	0.00089689	0.899660618	normal	0.04305938	0.727767428	normal	0.957973623	-0.144800319	normal	0.1774249	0.529235615	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04229|0|ggo:101127687|OXTR; oxytocin receptor; K04229 oxytocin receptor (A)	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Oxytocin signaling pathway (ko04921)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv;; Serpentine type 7TM GPCR chemoreceptor Srsx	Oxytocin receptor GN=OXTR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oxytocin receptor [Leptonychotes weddellii]
ENSG00000180917(CMTR2)	--	10.8725738	639	12.45884753	729	11.22081412	641	11.09753524	679	10.50803329	617	14.48511191	855	0.973315446	0.05663128	normal	0.924136445	-0.261484469	normal	0.699121193	0.406475533	normal	0.820652348	0.077848044	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: methylation (GO:0032259);; 	"K14590|0|hsa:55783|CMTR2, AFT, FTSJD1, HMTr2, MTr2; cap methyltransferase 2 (EC:2.1.1.296); K14590 cap2 methyltransferase [EC:2.1.1.296] (A)"	--	[A]	RNA processing and modification	FtsJ-like methyltransferase	Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 GN=CMTR2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 [Camelus dromedarius]
ENSG00000180919(OR56B4)	--	0.0697971	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:196335|OR56B4, OR11-67; olfactory receptor, family 56, subfamily B, member 4; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 56B4 GN=OR56B4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 56B4 [Ailuropoda melanoleuca]
ENSG00000180921(FAM83H)	--	22.61216	2763	24.53641	3056	21.62499	2844	28.55327	3450	29.08169	3534	32.56282	4137	0.949410699	0.28938429	normal	0.981204418	0.1881443	normal	0.25699609	0.532136107	normal	0.033040129	0.339632769	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1669)	Protein FAM83H GN=FAM83H OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM83H isoform X2 [Bos taurus] 
ENSG00000180929(GPR62)	--	0.0931783	3	0.119411	4	0.0291602	0	0.0303183	1	0.0599619	1	0.0304017	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08415|1.44693e-93|hsa:118442|GPR62, GPCR8, KPG_005; G protein-coupled receptor 62; K08415 G protein-coupled receptor 62 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 62 GN=GPR62 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: probable G-protein coupled receptor 62 [Ceratotherium simum simum]
ENSG00000180938(ZNF572)	--	0.646222	37	0.767204	44	0.367022	20	0.645265	37	0.680644	39	0.696136	40	0.982755411	-0.029603004	normal	0.976913783	-0.188567224	normal	0.803834054	0.940528502	normal	0.842457863	0.177695517	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 572 GN=ZNF572 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 572 isoform X1 [Equus caballus]
ENSG00000180957(PITPNB)	--	22.2428452	1124	24.04342634	1201	20.65442164	1031	22.6807593	1122	21.07510194	1059	18.93392114	919	0.980488524	-0.033355987	normal	0.959784885	-0.202688107	normal	0.964597961	-0.173928625	normal	0.53187707	-0.136465706	normal	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Phosphatidylinositol transfer protein	Phosphatidylinositol transfer protein beta isoform GN=PITPNB OS=Homo sapiens (Human) PE=1 SV=2	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: phosphatidylinositol transfer protein beta isoform [Bison bison bison]
ENSG00000180964(TCEAL8)	--	35.09006407	664	28.795259	550	31.9306106	602	34.8603867	683	38.87060867	728	33.13420561	635	0.974910196	0.009847607	normal	0.771363567	0.382164275	normal	0.97202553	0.068534016	normal	0.53221912	0.150717411	normal	--	--	--	--	--	--	--	Brain expressed X-linked like family	Transcription elongation factor A protein-like 8 GN=TCEAL8 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription elongation factor A protein-like 8 [Equus caballus] 
ENSG00000180979(LRRC57)	--	4.052591397	223	4.58484853	231	4.608063034	204	4.618536	254	4.072215	227	4.380833008	207	0.955976926	0.155945321	normal	0.965047565	-0.046321196	normal	0.966934661	0.012676881	normal	0.93111329	0.042307165	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat	Leucine-rich repeat-containing protein 57 GN=LRRC57 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 57 [Vicugna pacos]
ENSG00000180992(MRPL14)	--	31.3114	501	30.5164	498	32.6979	536	32.9992	538	31.2509	496	31.0676	501	0.969774308	0.07175095	normal	0.970664004	-0.027149569	normal	0.966946231	-0.105406163	normal	0.95908182	-0.021299502	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02874|4.24147e-104|hsa:64928|MRPL14, L14mt, L32mt, MRP-L14, MRP-L32, MRPL32, RMPL32, RPML32; mitochondrial ribosomal protein L14; K02874 large subunit ribosomal protein L14 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L14p/L23e	"39S ribosomal protein L14, mitochondrial (Precursor) GN=MRPL14 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L14, mitochondrial isoform X1 [Equus caballus]"
ENSG00000180998(GPR137C)	--	0.393744582	21	0.206731121	11	0.131740201	6	0.148315765	8	0.19878309	10	0.196067203	10	0.88715445	-1.268032782	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Integral membrane protein GPR137C GN=GPR137C OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: integral membrane protein GPR137C [Oryctolagus cuniculus]
ENSG00000180999(C1orf105)	--	0	0	0	0	0	0	0.333081031	5	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4548)	Uncharacterized protein C1orf105 GN=C1orf105 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf105 homolog isoform X2 [Canis lupus familiaris]
ENSG00000181004(BBS12)	--	1.608129157	85	1.564186575	83	1.661154409	87	1.501653914	80	2.048777342	98	2.082223975	111	0.970507352	-0.11613083	normal	0.959346601	0.214641511	normal	0.932327135	0.337968024	normal	0.788665466	0.160451618	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	TCP-1/cpn60 chaperonin family	Bardet-Biedl syndrome 12 protein GN=BBS12 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: Bardet-Biedl syndrome 12 protein-like [Galeopterus variegatus]
ENSG00000181007(ZFP82)	--	2.645595041	149	2.614346116	131	1.951256757	103	3.0888814	170	2.9732709	158	2.391317531	135	0.958592841	0.157865439	normal	0.942137941	0.246338688	normal	0.902099872	0.377172714	normal	0.545373684	0.251318888	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:284406|ZFP82, ZNF545; ZFP82 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; TFIIH C1-like domain;; NTF2 fold immunity protein"	Zinc finger protein 82 homolog GN=ZFP82 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 82 homolog isoform X1 [Panthera tigris altaica]
ENSG00000181013(C17orf47)	--	0	0	0	0	0	0	0	0	0	0	0.0221647	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4655)	Uncharacterized protein C17orf47 GN=C17orf47 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C17orf47 homolog [Ceratotherium simum simum]
ENSG00000181019(NQO1)	--	1118.25235	26467	1190.456792	31327	1059.682077	27137	677.5345681	17134	663.6452183	16273	794.9268531	19882	0.047576235	-0.658117052	normal	2.65E-06	-0.966286997	normal	0.861243273	-0.45705991	normal	3.75E-05	-0.693375305	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; 	"K00355|0|pon:100172039|NQO1; NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2); K00355 NAD(P)H dehydrogenase (quinone) [EC:1.6.5.2] (A)"	Ubiquinone and other terpenoid-quinone biosynthesis (ko00130)	--	--	Flavodoxin-like fold;; NADPH-dependent FMN reductase	NAD(P)H dehydrogenase [quinone] 1 GN=NQO1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NAD(P)H dehydrogenase [quinone] 1 isoform X1 [Vicugna pacos]
ENSG00000181026(AEN)	--	35.60367146	2014	40.50545542	2356	37.03808611	2126	36.04640259	2010	40.19134508	2233	44.07119416	2437	0.986639496	-0.03367473	normal	0.985258525	-0.098717747	normal	0.975915798	0.188547853	normal	0.95263579	0.019617942	normal	[L]	"Replication, recombination and repair"	--	"K18340|0|hsa:64782|AEN, ISG20L1, pp12744; apoptosis enhancing nuclease; K18340 apoptosis-enhancing nuclease [EC:3.1.-.-] (A)"	--	[L]	"Replication, recombination and repair"	Exonuclease	Apoptosis-enhancing nuclease GN=AEN OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: apoptosis-enhancing nuclease isoform X1 [Sus scrofa] 
ENSG00000181027(FKRP)	--	16.86954795	761	19.07958611	903	17.21477896	787	13.97213953	591	20.81298585	792	21.30275065	813	0.7318734	-0.39466361	normal	0.951910239	-0.210275767	normal	0.976432959	0.038527432	normal	0.496045113	-0.178824512	normal	[M]	Cell wall/membrane/envelope biogenesis	--	--	--	--	--	LicD family	Fukutin-related protein GN=FKRP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: fukutin-related protein [Orcinus orca]
ENSG00000181029(TRAPPC5)	--	60.93034571	646	52.86023496	559	51.33749837	553	47.85916587	487	58.91297331	551	58.98037742	560	0.611113159	-0.437242379	normal	0.971396563	-0.042107781	normal	0.972905266	0.009829193	normal	0.524567328	-0.158527861	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Transport protein particle (TRAPP) component	Trafficking protein particle complex subunit 5 GN=TRAPPC5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 5 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000181031(RPH3AL)	--	22.00458161	1135	25.03619657	1119	24.92421472	1110	16.54447428	965	19.63661949	1026	23.68073362	1123	0.931117776	-0.264534819	normal	0.970707122	-0.146399154	normal	0.980847992	0.008495302	normal	0.542842435	-0.13216107	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	FYVE-type zinc finger	Rab effector Noc2 GN=RPH3AL OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: rab effector Noc2 [Ailuropoda melanoleuca]
ENSG00000181035(SLC25A42)	--	1.209182	64	1.049414379	57	0.997233196	54	1.186778053	63	1.284612863	68	0.746663294	40	0.975815195	-0.052287136	normal	0.966631726	0.227611799	normal	0.953848574	-0.42729618	normal	0.958484282	-0.055806655	normal	--	--	--	"K15085|0|ptr:736307|SLC25A42; solute carrier family 25, member 42; K15085 solute carrier family 25, member 42 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial coenzyme A transporter SLC25A42 GN=SLC25A42 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: mitochondrial coenzyme A transporter SLC25A42 [Ceratotherium simum simum]
ENSG00000181045(SLC26A11)	--	9.924217481	400	10.42191401	354	6.956322866	319	10.16031601	374	9.8312708	408	10.7094983	425	0.961452359	-0.127288209	normal	0.950008902	0.182665892	normal	0.745730291	0.403950456	normal	0.615744084	0.148725622	normal	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14708|0|hsa:284129|SLC26A11; solute carrier family 26 (anion exchanger), member 11; K14708 solute carrier family 26 (sodium-independent sulfate anion transporter), member 11 (A)"	--	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain	Sodium-independent sulfate anion transporter OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-independent sulfate anion transporter [Equus caballus] 
ENSG00000181061(HIGD1A)	--	67.59502236	1168	73.03991076	1273	73.20355596	1240	88.06305701	1552	76.0294837	1312	67.10041875	1162	0.789120667	0.378822491	normal	0.98187792	0.022082902	normal	0.977823185	-0.101893097	normal	0.630351554	0.107170392	normal	--	--	--	--	--	[R]	General function prediction only	Hypoxia induced protein conserved region	"HIG1 domain family member 1A, mitochondrial GN=HIGD1A OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: HIG1 domain family member 1A, mitochondrial isoform X2 [Oryctolagus cuniculus]"
ENSG00000181085(MAPK15)	--	0.025708332	1	0.02500628	1	0.1222617	4	0	0	0.174576585	2	0.123070187	5	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08293|0|hsa:225689|MAPK15, ERK7, ERK8; mitogen-activated protein kinase 15 (EC:2.7.11.24); K08293 mitogen-activated protein kinase [EC:2.7.11.24] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase 15 GN=MAPK15 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 15 isoform X2 [Galeopterus variegatus]
ENSG00000181090(EHMT1)	--	21.526331	1784	22.10182606	1818	21.25566144	1904	20.23535939	1898	24.50770674	1891	18.55495269	1697	0.98513575	0.05848328	normal	0.98547246	0.03534178	normal	0.974677742	-0.174191717	normal	0.926977546	-0.026648445	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; 	K11420|0|pps:100968253|EHMT1; euchromatic histone-lysine N-methyltransferase 1; K11420 euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] (A)	Lysine degradation (ko00310)	[BK]	Chromatin structure and dynamics;; Transcription	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SET domain;; Pre-SET motif	Histone-lysine N-methyltransferase EHMT1 GN=EHMT1 OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase EHMT1 [Galeopterus variegatus]
ENSG00000181104(F2R)	--	40.424414	2383	29.4172	1763	34.822	2068	23.1628	1392	23.4857	1404	17.93050004	1076	0.000225793	-0.805763418	normal	0.861798197	-0.349579259	normal	2.26E-06	-0.949869087	normal	0.000898343	-0.704252059	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K03914|0|hsa:2149|F2R, CF2R, HTR, PAR-1, PAR1, TR; coagulation factor II (thrombin) receptor; K03914 coagulation factor II (thrombin) receptor (A)"	Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Complement and coagulation cascades (ko04610);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Pathways in cancer (ko05200)	--	--	7 transmembrane receptor (rhodopsin family)	Proteinase-activated receptor 1 (Precursor) GN=F2R OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: proteinase-activated receptor 1 [Odobenus rosmarus divergens]
ENSG00000181135(ZNF707)	--	5.57514852	271	7.168558667	330	7.97523285	326	7.395252921	351	8.849793311	384	8.170516906	384	0.860392047	0.340645033	normal	0.946070343	0.196378836	normal	0.936868442	0.226971773	normal	0.348758594	0.250784153	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:286075|ZNF707; zinc finger protein 707; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 707 GN=ZNF707 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 707 [Galeopterus variegatus]
ENSG00000181143(MUC16)	--	0.03316812	25	0.01114187	8	0	0	0.01778795	18	0.00844946	8	0.013408096	14	0.980167777	-0.470534008	normal	--	--	--	--	--	--	--	--	--	--	--	--	"K16145|0|hsa:94025|MUC16, CA125; mucin 16, cell surface associated; K16145 mucin-16 (A)"	--	--	--	SEA domain	Mucin-16 GN=MUC16 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mucin-16-like [Ceratotherium simum simum]
ENSG00000181163(NPM1)	--	644.956225	19761	698.6973	21691	656.712546	20171	771.44136	24261	727.24022	22115	662.790186	20641	0.99138767	0.265132168	normal	0.997965299	0.00650167	normal	0.997902251	0.024936968	normal	0.713737845	0.099302829	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K11276|2.14981e-173|ptr:740704|NPM1; nucleophosmin (nucleolar phosphoprotein B23, numatrin); K11276 nucleophosmin 1 (A)"	--	--	--	Nucleoplasmin	Nucleophosmin GN=NPM1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	nucleophosmin [Oryctolagus cuniculus] 
ENSG00000181191(PJA1)	--	9.7104353	495	8.12145157	487	8.722743786	472	9.675359085	506	10.07486671	525	6.742563472	394	0.971742393	0.000873913	normal	0.967692735	0.086709727	normal	0.916383448	-0.267941697	normal	0.885548055	-0.050958629	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10633|0|mcf:102123650|PJA1; praja ring finger 1, E3 ubiquitin protein ligase; K10633 E3 ubiquitin-protein ligase Praja1 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase Praja-1 GN=PJA1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase Praja-1 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000181192(DHTKD1)	--	11.189296	1135	8.797545258	867	9.56677767	979	9.700041304	995	11.43047186	1148	8.250610196	822	0.952825583	-0.220437124	normal	0.775027662	0.383009912	normal	0.930486826	-0.260022968	normal	0.949718104	-0.029346153	normal	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624);; "	"K15791|0|hsa:55526|DHTKD1, AMOXAD, CMT2Q; dehydrogenase E1 and transketolase domain containing 1 (EC:1.2.4.2); K15791 probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 [EC:1.2.4.2] (A)"	--	[G]	Carbohydrate transport and metabolism	"Transketolase, pyrimidine binding domain;; Dehydrogenase E1 component"	"Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (Precursor) GN=DHTKD1 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000181218(HIST3H2A)	--	11.9533	149	10.5919	135	8.05662	104	5.87528	75	7.5704	95	10.055	128	0.009186808	-1.006259164	down	0.759511919	-0.521386281	normal	0.940061578	0.287494346	normal	0.320270042	-0.400835051	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|2.39697e-71|oas:101104790|histone H2A type 1-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 3 GN=HIST3H2A OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 1-like [Ovis aries]
ENSG00000181220(ZNF746)	--	8.235625	638	9.032516596	709	8.00996072	633	8.155136	625	8.988286	692	8.679504	673	0.9726356	-0.060385566	normal	0.97350602	-0.05631855	normal	0.971878667	0.079924356	normal	0.972572149	-0.013795614	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:155061|ZNF746, PARIS; zinc finger protein 746; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; Zinc finger protein;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein 746 GN=ZNF746 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 746 [Odobenus rosmarus divergens]
ENSG00000181222(POLR2A)	--	38.625801	5625	38.859891	5629	37.402002	5444	30.1914515	4349	27.35830115	3961	35.64180148	5210	0.838611768	-0.401876411	normal	0.339344799	-0.528270373	normal	0.99302713	-0.071654787	normal	0.048962148	-0.325330438	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Cellular Component: DNA-directed RNA polymerase II, core complex (GO:0005665);; Biological Process: transcription, DNA-templated (GO:0006351);; Biological Process: transcription from RNA polymerase II promoter (GO:0006366);; "	"K03006|0|hgl:101725588|Polr2a; polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; K03006 DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Huntington's disease (ko05016);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	"RNA polymerase Rpb1, domain 1;; RNA polymerase Rpb1, domain 5;; RNA polymerase Rpb1, domain 6;; RNA polymerase Rpb1, domain 2;; RNA polymerase Rpb1, domain 7;; RNA polymerase Rpb1, domain 3;; RNA polymerase Rpb1, domain 4;; RNA polymerase Rpb1 C-terminal repeat"	DNA-directed RNA polymerase II subunit RPB1 GN=POLR2A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase II subunit RPB1 [Mustela putorius furo]
ENSG00000181234(TMEM132C)	--	0	0	0	0	0	0	0.00954325	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17599|0|hsa:92293|TMEM132C, PPP1R152; transmembrane protein 132C; K17599 transmembrane protein 132 (A)"	--	[S]	Function unknown	--	Transmembrane protein 132C (Precursor) GN=TMEM132C OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 132C [Equus przewalskii]
ENSG00000181240(SLC25A41)	--	0.321545	8	0.234772	6	0.268887	6	0.0782078	2	0.195255	4	0.118586	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K14684|0|hsa:284427|SLC25A41, APC4; solute carrier family 25, member 41; K14684 solute carrier family 25 (mitochondrial phosphate transporter), member 23/24/25/41 (A)"	--	[F]	Nucleotide transport and metabolism	Mitochondrial carrier protein	Solute carrier family 25 member 41 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 41 [Camelus ferus] 
ENSG00000181264(TMEM136)	--	6.509779039	235	5.878863424	265	7.636714171	301	5.761291132	249	4.979742726	224	6.13731635	270	0.965977973	0.052320397	normal	0.924376936	-0.262289929	normal	0.954302157	-0.164223879	normal	0.721808438	-0.129118582	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	TLC domain	Transmembrane protein 136 GN=TMEM136 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 136 isoform 1 [Dasypus novemcinctus]
ENSG00000181274(FRAT2)	--	2.73371	90	3.07331	106	2.59262	90	3.105	104	4.34236	144	6.90463	231	0.964024386	0.174973981	normal	0.868069487	0.415474899	normal	1.27E-06	1.337073608	up	0.263700548	0.724995761	normal	--	--	--	K03096|1.57055e-111|hsa:23401|FRAT2; frequently rearranged in advanced T-cell lymphomas 2; K03096 frequently rearranged in advanced T-cell lymphomas 2 (A)	Wnt signaling pathway (ko04310)	--	--	Glycogen synthase kinase-3 binding	GSK-3-binding protein FRAT2 GN=FRAT2 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: GSK-3-binding protein FRAT2 [Orycteropus afer afer]
ENSG00000181291(TMEM132E)	--	0.011570436	1	0	0	0	0	0.01167395	1	0.022548322	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K17599|0|cjc:100385808|TMEM132E; transmembrane protein 132E; K17599 transmembrane protein 132 (A)	--	[S]	Function unknown	--	Transmembrane protein 132E (Precursor) GN=TMEM132E OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 132E [Mustela putorius furo]
ENSG00000181315(ZNF322)	--	5.565343049	433	6.679481853	539	5.517624406	439	4.486557662	359	5.257412226	418	6.238746254	472	0.892947409	-0.300044117	normal	0.768585034	-0.38697231	normal	0.966611858	0.095955632	normal	0.443040152	-0.196523128	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; TFIIH C1-like domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 322 GN=ZNF322 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 322-like [Orcinus orca]
ENSG00000181322(NME9)	--	0.213439	8	0.58959508	10	0.89002023	9	0.69791305	14	0.5895815	9	0.46441785	11	--	--	--	--	--	--	--	--	--	--	--	--	[F]	Nucleotide transport and metabolism	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Nucleoside diphosphate kinase;; Thioredoxin	Thioredoxin domain-containing protein 6 GN=NME9 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin domain-containing protein 6 [Physeter catodon]
ENSG00000181333(HEPHL1)	--	0.00972589	1	0.0097164	1	0	0	0.0484695	5	0.00946358	0	0.0193216	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Multicopper oxidase;; Multicopper oxidase	Hephaestin-like protein 1 (Precursor) GN=HEPHL1 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: hephaestin-like protein 1 [Galeopterus variegatus]
ENSG00000181350(LRRC75A)	--	1.356519109	76	0.723949379	42	1.222898035	61	0.68468439	38	0.562001	26	0.489602	28	0.204214297	-1.001618606	normal	0.915946979	-0.681812132	normal	0.252485569	-1.090802743	normal	0.046729969	-0.982369192	normal	--	--	--	--	--	--	--	--	Leucine-rich repeat-containing protein 75A GN=LRRC75A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein FAM211A [Equus caballus]
ENSG00000181355(OFCC1)	--	0.082860656	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Orofacial cleft 1 candidate gene 1 protein GN=OFCC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC102892169 [Pteropus alecto]
ENSG00000181378(CFAP65)	--	0.0353088	1	0.018655829	1	0.00717901	0	0.057285879	4	0.05579058	3	0.014621081	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MSP (Major sperm protein) domain	Coiled-coil domain-containing protein 108 GN=CCDC108 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 108, partial [Ceratotherium simum simum]"
ENSG00000181381(DDX60L)	--	5.915699286	550	4.412747061	524	5.237400508	630	10.37510339	1140	12.47177253	993	10.46370418	959	6.92E-07	1.018680178	up	5.85E-05	0.898885258	normal	0.07734213	0.596718277	normal	2.87E-08	0.838169083	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[R]	General function prediction only	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Probable ATP-dependent RNA helicase DDX60-like GN=DDX60L OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: probable ATP-dependent RNA helicase DDX60-like [Ceratotherium simum simum]
ENSG00000181392(SYNE4)	--	31.45845829	500	25.25216692	423	37.31724786	595	23.43508745	365	23.58365942	357	28.6364105	450	0.483098939	-0.483118268	normal	0.917785452	-0.265126949	normal	0.702332355	-0.410053652	normal	0.126146119	-0.393279251	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Nuclear envelope localisation domain	Nesprin-4 GN=SYNE4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: nesprin-4 [Galeopterus variegatus]
ENSG00000181396(OGFOD3)	--	13.404862	720	14.5303769	828	11.8479357	691	12.962073	766	14.08961994	803	13.4017053	718	0.974646189	0.058394407	normal	0.974903815	-0.065535785	normal	0.974639779	0.04690598	normal	0.983948554	0.009035318	normal	--	--	--	--	--	--	--	2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily	2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 GN=OGFOD3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 isoform X2 [Canis lupus familiaris]
ENSG00000181404(WASHC1)	--	14.05031377	603	15.19081036	671	15.15446927	645	13.42629043	581	13.72518502	587	15.3691924	696	0.970291864	-0.084233426	normal	0.945630385	-0.213863027	normal	0.970349098	0.101268086	normal	0.833277129	-0.062613164	normal	--	--	--	"K18461|0|hsa:100287171|WASH1, FAM39E, WASH; WAS protein family homolog 1; K18461 WAS protein family homolog 1 (A)"	--	--	--	WAHD domain of WASH complex	WAS protein family homolog 1 GN=WASH1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: WAS protein family homolog 1-like [Pteropus alecto]
ENSG00000181408(UTS2R)	--	0	0	0	0	0.0606831	0	0.0637806	1	0.0630661	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04241|0|hsa:2837|UTS2R, GPR14, UR-2-R, UTR, UTR2; urotensin 2 receptor; K04241 urotensin 2 receptor (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Urotensin-2 receptor GN=UTS2R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: urotensin-2 receptor [Equus przewalskii]
ENSG00000181409(AATK)	--	0.363454003	36	0.311275154	31	0.282416713	28	0.144307721	14	0.34158271	34	0.173186	17	0.479554134	-1.301311102	normal	0.98235223	0.106861204	normal	0.961166391	-0.680572903	normal	0.427808745	-0.568102242	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17480|0|hsa:9625|AATK, AATYK, AATYK1, LMR1, LMTK1, PPP1R77, p35BP; apoptosis-associated tyrosine kinase (EC:2.7.11.1); K17480 lemur tyrosine kinase 1 [EC:2.7.10.1] (A)"	--	--	--	Protein tyrosine kinase;; Protein kinase domain	Serine/threonine-protein kinase LMTK1 GN=AATK OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase LMTK1 isoform X1 [Bubalus bubalis]
ENSG00000181418(DDN)	--	0.267176	20	0.400324	31	0.266352	20	0.423372	32	0.335949	25	0.144748	11	0.962467021	0.609922847	normal	0.979350761	-0.314641088	normal	0.97131957	-0.789314314	normal	0.957142353	-0.086738841	normal	--	--	--	--	--	--	--	"Nephrin and CD2AP-binding protein, Dendrin"	Dendrin GN=DDN OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: dendrin [Galeopterus variegatus]
ENSG00000181444(ZNF467)	--	10.25002	336	6.35766	223	6.70326	234	2.031683	75	3.337968	120	2.106487	71	0	-2.171276632	down	0.006800592	-0.906913252	normal	2.01E-10	-1.707683288	down	2.94E-05	-1.597171527	down	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 467 GN=ZNF467 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 467 [Oryctolagus cuniculus]
ENSG00000181449(SOX2)	--	3.08718	138	2.43481	110	2.42534	110	6.24493	281	8.80944	395	6.31511	285	0.00052574	0.987216132	normal	8.66E-15	1.808922456	up	1.23E-07	1.353180978	up	1.79E-06	1.403443729	up	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K16796|0|hsa:6657|SOX2, ANOP3, MCOPS3; SRY (sex determining region Y)-box 2; K16796 transcription factor SOX2 (SOX group B) (A)"	Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550)	[K]	Transcription	SOX transcription factor;; HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-2 GN=SOX2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor SOX-2 [Dasypus novemcinctus]
ENSG00000181450(ZNF678)	--	1.990051079	200	1.783200582	219	1.691270946	153	2.298235174	201	1.869004712	167	2.00241665	190	0.966803541	-0.023457013	normal	0.816892012	-0.409262195	normal	0.918591353	0.301497256	normal	0.910062506	-0.057742703	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; C1-like domain"	Zinc finger protein 678 GN=ZNF678 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 420-like [Ursus maritimus]
ENSG00000181458(TMEM45A)	--	5.20493791	121	4.730872967	103	4.41121332	101	3.118075028	71	1.517061343	34	4.259978906	98	0.252313075	-0.786745131	normal	5.71E-05	-1.578097687	down	0.970307089	-0.051017546	normal	0.118441402	-0.699443877	normal	--	--	--	--	--	--	--	Family of unknown function (DUF716)	Transmembrane protein 45A GN=TMEM45A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 45A isoform X3 [Galeopterus variegatus]
ENSG00000181467(RAP2B)	--	9.9769	1188	13.3904	1606	8.90149	1048	11.0056	1324	11.0868	1318	14.6312	1742	0.976065034	0.125382376	normal	0.911063727	-0.306229181	normal	0.002890842	0.723995601	normal	0.699842325	0.169450174	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07838|1.05738e-120|umr:103677700|RAP2B; RAP2B, member of RAS oncogene family; K07838 Ras-related protein Rap-2B (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	Ras-related protein Rap-2b (Precursor) GN=RAP2B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	ras-related protein Rap-2b [Bos taurus] 
ENSG00000181472(ZBTB2)	--	4.665732	275	5.641765	329	5.6037736	326	6.780015837	398	6.050719479	356	5.175082512	307	0.479457385	0.500170098	normal	0.96378521	0.091956696	normal	0.964126278	-0.094473061	normal	0.578327059	0.168257973	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10489|0|pps:100982274|ZBTB2; zinc finger and BTB domain containing 2; K10489 zinc finger and BTB domain-containing protein 2 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 2 GN=ZBTB2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 2 [Oryctolagus cuniculus] 
ENSG00000181481(RNF135)	--	21.36953147	726	19.80715146	630	17.8579523	614	18.881192	653	25.28671353	793	20.32472745	670	0.956689491	-0.183309508	normal	0.885941497	0.309878214	normal	0.968026185	0.117354221	normal	0.766701535	0.081982125	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	K16272|0|pon:100439670|RNF135; ring finger protein 135; K16272 E3 ubiquitin-protein ligase RNF135 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF135 GN=RNF135 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF135 isoform X1 [Loxodonta africana]
ENSG00000181513(ACBD4)	--	13.70506916	479	10.747918	385	12.67354725	453	11.189554	392	9.672072	335	8.974768	312	0.873481686	-0.318871368	normal	0.938123245	-0.22119159	normal	0.295345976	-0.544054959	normal	0.106596757	-0.36384412	normal	[I]	Lipid transport and metabolism	Molecular Function: fatty-acyl-CoA binding (GO:0000062);; 	--	--	[I]	Lipid transport and metabolism	Acyl CoA binding protein	Acyl-CoA-binding domain-containing protein 4 GN=ACBD4 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: acyl-CoA-binding domain-containing protein 4 [Camelus bactrianus]
ENSG00000181523(SGSH)	--	8.4730859	626	6.966471939	560	8.118083117	629	10.191136	688	12.15866	795	11.577837	790	0.969568529	0.105167382	normal	0.444002987	0.483001658	normal	0.872872947	0.319813683	normal	0.115623026	0.304021021	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K01565|0|hsa:6448|SGSH, HSS, MPS3A, SFMD; N-sulfoglucosamine sulfohydrolase (EC:3.10.1.1); K01565 N-sulfoglucosamine sulfohydrolase [EC:3.10.1.1] (A)"	Glycosaminoglycan degradation (ko00531);; Lysosome (ko04142)	[R]	General function prediction only	Sulfatase;; Type I phosphodiesterase / nucleotide pyrophosphatase	N-sulphoglucosamine sulphohydrolase (Precursor) GN=SGSH OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: N-sulphoglucosamine sulphohydrolase [Equus caballus]
ENSG00000181541(MAB21L2)	--	0	0	0	0	0.0819998	4	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Mab-21 protein	Protein mab-21-like 2 GN=MAB21L2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein mab-21-like 2 [Physeter catodon]
ENSG00000181544(FANCB)	--	4.170671642	519	5.145053638	589	5.466805924	632	3.576386303	475	3.04726113	432	3.865144243	484	0.958389221	-0.158149671	normal	0.530665207	-0.467255942	normal	0.745191793	-0.392133425	normal	0.090516264	-0.343925775	normal	--	--	--	"K10889|0|hsa:2187|FANCB, FA2, FAAP90, FAAP95, FAB, FACB; Fanconi anemia, complementation group B; K10889 fanconi anemia group B protein (A)"	Fanconi anemia pathway (ko03460)	--	--	--	Fanconi anemia group B protein GN=FANCB OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: Fanconi anemia group B protein [Ailuropoda melanoleuca]
ENSG00000181555(SETD2)	--	8.981307728	1614	9.588261778	1714	9.52314607	1663	9.040859712	1643	11.29553145	1891	9.316441433	1668	0.984882058	-0.005135517	normal	0.981007694	0.120254655	normal	0.985136667	-0.003956729	normal	0.889452211	0.038650878	normal	[R]	General function prediction only	"Molecular Function: protein binding (GO:0005515);; Cellular Component: chromosome (GO:0005694);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; "	"K11423|0|hsa:29072|SETD2, HBP231, HIF-1, HIP-1, HYPB, KMT3A, SET2, p231HBP; SET domain containing 2 (EC:2.1.1.43); K11423 histone-lysine N-methyltransferase SETD2 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SRI (Set2 Rpb1 interacting) domain;; SET domain;; WW domain	Histone-lysine N-methyltransferase SETD2 GN=HSPC069 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: histone-lysine N-methyltransferase SETD2 [Equus caballus] 
ENSG00000181577(C6orf223)	--	0.0809102	5	0.0793101	4	0.11469635	6	0.3698187	27	0.34972293	31	0.2751076	16	0.101683993	2.099847257	normal	0.004830972	2.542275235	up	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C6orf223 GN=C6orf223 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C6orf223 homolog [Orcinus orca]
ENSG00000181585(TMIE)	--	0.0994947	4	0	0	0.166556	6	0.0494235	2	0.097402	3	0.0494962	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane inner ear expressed protein (Precursor) GN=TMIE OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane inner ear expressed protein [Camelus ferus]
ENSG00000181588(MEX3D)	--	12.8748	509	12.08171565	520	13.1622	535	17.082	698	17.94191	727	11.748438	496	0.65261899	0.423633232	normal	0.535421764	0.460878806	normal	0.96551339	-0.11714621	normal	0.300955342	0.274635268	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K15686|0|hsa:399664|MEX3D, MEX-3D, MEX3, OK/SW-cl.4, RKHD1, RNF193, TINO; mex-3 RNA binding family member D; K15686 RNA-binding protein MEX3 (A)"	--	[R]	General function prediction only	"KH domain;; KH domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RNA-binding protein MEX3D GN=MEX3D OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RNA-binding protein MEX3D [Odobenus rosmarus divergens]
ENSG00000181609(OR52D1)	--	0	0	0	0	0.261382	2	0	0	0	0	0.174605	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:390066|OR52D1, OR11-43; olfactory receptor, family 52, subfamily D, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 52D1 GN=OR52D1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	"olfactory receptor, family 52, subfamily D, member 1 (predicted) [Sorex araneus]"
ENSG00000181610(MRPS23)	--	50.55263513	1215	41.862223	1105	53.567964	1180	55.79899	1242	54.3454263	1292	44.25016	1100	0.981889065	0.000875501	normal	0.960576413	0.203874895	normal	0.976476387	-0.109429489	normal	0.90801502	0.032760892	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K17402|7.18261e-138|hsa:51649|MRPS23, HSPC329, MRP-S23; mitochondrial ribosomal protein S23; K17402 small subunit ribosomal protein S23 (A)"	--	--	--	Mitochondrial ribosomal protein S23;; Mitochondrial ribosomal protein S25	"28S ribosomal protein S23, mitochondrial GN=MRPS23 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S23, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000181617(FDCSP)	--	0.191691	1	0	0	0.187053	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Follicular dendritic cell secreted peptide	Follicular dendritic cell secreted peptide (Precursor) GN=FDCSP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	--
ENSG00000181625(SLX1B)	--	1.445821087	4	0	0	0.168713	1	0	0	0	0	0.338371139	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15078|5.45381e-164|hsa:548593|SLX1A, GIYD1; SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae); K15078 structure-specific endonuclease subunit SLX1 [EC:3.6.1.-] (A)"	Fanconi anemia pathway (ko03460)	[R]	General function prediction only	GIY-YIG catalytic domain	Structure-specific endonuclease subunit SLX1 {ECO:0000255|HAMAP-Rule:MF_03100} OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: structure-specific endonuclease subunit SLX1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000181626(ANKRD62)	--	0.0616468	4	0	0	0.0614147	3	0	0	0.0149219	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 62 GN=ANKRD62 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	"hypothetical protein M91_10244, partial [Bos mutus]"
ENSG00000181631(P2RY13)	--	0	0	0.0496697	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08388|0|hsa:53829|P2RY13, GPCR1, GPR86, GPR94, P2Y13, SP174; purinergic receptor P2Y, G-protein coupled, 13; K08388 purinergic receptor P2Y, G protein-coupled, 13 (A)"	Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv	P2Y purinoceptor 13 GN=P2RY13 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	hypothetical protein PANDA_004457 [Ailuropoda melanoleuca]
ENSG00000181634(TNFSF15)	--	0.065985766	7	0.121458996	9	0.056571777	5	0.74098769	86	1.57147144	178	1.2939673	148	2.04E-12	3.330386791	up	0	4.074139404	up	0	4.513669152	up	4.35E-09	4.273771444	up	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	K05478|0|ggo:101141431|TNFSF15; tumor necrosis factor ligand superfamily member 15; K05478 tumor necrosis factor ligand superfamily member 15 (A)	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNF(Tumour Necrosis Factor) family	"Tumor necrosis factor ligand superfamily member 15, secreted form GN=TNFSF15 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor ligand superfamily member 15 [Ailuropoda melanoleuca] 
ENSG00000181638(ZFP41)	--	39.165789	1513	38.75930505	1603	36.81871001	1574	29.70173936	1284	29.309114	1304	35.676703	1589	0.93733581	-0.267303978	normal	0.898067557	-0.318922852	normal	0.984612611	0.00538699	normal	0.318400357	-0.187677279	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 41 homolog GN=ZFP41 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 41 homolog [Galeopterus variegatus]
ENSG00000181649(PHLDA2)	--	34.3366	412	24.1794	292	35.0495	438	34.5025	421	31.0481	380	25.7678	316	0.970030632	0.000342369	normal	0.837388803	0.356979726	normal	0.532430917	-0.477348506	normal	0.909580528	-0.053494036	normal	--	--	--	--	--	--	--	--	Pleckstrin homology-like domain family A member 2 GN=PHLDA2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology-like domain family A member 2 [Sorex araneus]
ENSG00000181652(ATG9B)	--	0.083747701	6	0.016354753	1	0.063446287	4	0.16842	12	0.184899246	17	0.090892551	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K17907|0|hsa:285973|ATG9B, APG9L2, NOS3AS, SONE; autophagy related 9B; K17907 autophagy-related protein 9 (A)"	--	[R]	General function prediction only	Autophagy protein Apg9	Autophagy-related protein 9B GN=ATG9B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: autophagy-related protein 9B isoform X1 [Oryctolagus cuniculus]
ENSG00000181656(GPR88)	--	0	0	0	0	0	0	0.0217476	1	0.0423718	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08422|4.54237e-100|ptr:735527|GPR88; G protein-coupled receptor 88; K08422 G protein-coupled receptor 88 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srx	Probable G-protein coupled receptor 88 GN=GPR88 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 88 [Odobenus rosmarus divergens]
ENSG00000181666(HKR1)	--	7.440868259	474	8.569248631	525	6.46850886	421	9.090342084	496	8.450497955	504	9.292430504	536	0.97090023	0.034511441	normal	0.968417391	-0.080084778	normal	0.848124311	0.339039496	normal	0.75865949	0.09201037	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:284459|HKR1, ZNF875; HKR1, GLI-Kruppel zinc finger family member; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Probable zinc-binding domain"	Krueppel-related zinc finger protein 1 GN=HKR1 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: Krueppel-related zinc finger protein 1 isoform X2 [Galeopterus variegatus]
ENSG00000181690(PLAG1)	--	0.897372237	72	0.45440276	47	0.577881525	62	0.640774062	58	0.438733783	45	0.489927062	43	0.954443484	-0.334798547	normal	0.978128442	-0.081482587	normal	0.920751583	-0.520883961	normal	0.594330135	-0.332043128	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein PLAG1 GN=PLAG1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein PLAG1 isoform X1 [Tupaia chinensis] 
ENSG00000181704(YIPF6)	--	15.61029	1539	16.29387	1582	14.89653	1441	15.63703	1516	14.65429	1426	18.00907	1760	0.98338589	-0.052502929	normal	0.972078995	-0.171029875	normal	0.933612596	0.279947394	normal	0.942436071	0.022685263	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Yip1 domain	Protein YIPF6 GN=YIPF6 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein YIPF6 [Condylura cristata]
ENSG00000181722(ZBTB20)	--	2.704101916	1214	3.706121724	1638	3.680451119	1607	3.823584298	1717	4.016868014	1803	3.902340865	1760	0.47198259	0.46878829	normal	0.980711809	0.116934555	normal	0.98028011	0.122803596	normal	0.213664258	0.222884117	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10501|0|ptr:470888|ZBTB20; zinc finger and BTB domain containing 20; K10501 zinc finger and BTB domain-containing protein 20 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 20 GN=ZBTB20 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 20 isoformX2 [Canis lupus familiaris] 
ENSG00000181744(C3orf58)	--	9.987187324	568	11.57497854	663	11.42164279	607	9.039785	503	8.416174294	470	9.70681222	556	0.946717989	-0.205573397	normal	0.334403306	-0.516368324	normal	0.964459389	-0.134552686	normal	0.168578689	-0.286530685	normal	--	--	--	--	--	--	--	Protein-kinase domain of FAM69	Deleted in autism protein 1 (Precursor) GN=C3orf58 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	deleted in autism protein 1 [Bos taurus] 
ENSG00000181751(C5orf30)	--	16.156876	720	15.23524026	677	15.29331488	663	10.36618163	463	10.31520342	449	10.32402429	484	0.024413614	-0.666028891	normal	0.084246828	-0.612175203	normal	0.526931394	-0.461057162	normal	0.000820624	-0.582497656	normal	--	--	--	--	--	--	--	UNC119-binding protein C5orf30 homologue	UNC119-binding protein C5orf30 GN=C5orf30 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: UNC119-binding protein C5orf30 homolog [Echinops telfairi]
ENSG00000181754(AMIGO1)	--	1.033602	101	0.933614449	86	0.870445077	78	1.0564273	84	0.94636685	88	0.836990388	68	0.94809804	-0.2918499	normal	0.970959711	0.011539707	normal	0.966804782	-0.202032202	normal	0.788665466	-0.164957431	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain	Amphoterin-induced protein 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: amphoterin-induced protein 1 [Canis lupus familiaris]
ENSG00000181773(GPR3)	--	1.19985	38	1.15754	37	1.39035	44	0.882282	28	0.491733	15	0.690501	22	0.9681375	-0.450117894	normal	0.516551024	-1.241803675	normal	0.729603243	-0.96072822	normal	0.132363332	-0.894412196	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04311|1.41134e-171|pps:100978876|GPR3; G protein-coupled receptor 3; K04311 G protein-coupled receptor 3 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 3 GN=GPR3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 3 [Oryctolagus cuniculus] 
ENSG00000181781(ODF3L2)	--	0.042702375	1	0	0	0	0	0	0	0.08241866	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sperm-tail PG-rich repeat	Outer dense fiber protein 3-like protein 2 GN=ODF3L2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: outer dense fiber protein 3-like protein 2 [Galeopterus variegatus]
ENSG00000181788(SIAH2)	--	10.995381	377	9.998906556	373	9.638644988	361	11.53953	410	13.31077145	490	12.84355001	476	0.965793183	0.089875843	normal	0.804295921	0.370864092	normal	0.767556247	0.389246942	normal	0.220280848	0.287862291	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Biological Process: multicellular organismal development (GO:0007275);; 	K08742|0|ptr:460781|SIAH2; siah E3 ubiquitin protein ligase 2; K08742 E3 ubiquitin-protein ligase SIAH2 [EC:6.3.2.19] (A)	--	[R]	General function prediction only	Seven in absentia protein family	E3 ubiquitin-protein ligase SIAH2 GN=SIAH2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase SIAH2 [Mustela putorius furo]
ENSG00000181789(COPG1)	--	37.974593	2318	36.188873	2173	32.73912544	2071	37.98388716	2300	45.34380546	2610	38.29571622	2416	0.987732682	-0.042050987	normal	0.963401525	0.242780727	normal	0.970305908	0.213856744	normal	0.50090687	0.137773177	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: COPI vesicle coat (GO:0030126);; 	"K17267|0|pps:100988002|COPG1; coatomer protein complex, subunit gamma 1; K17267 coatomer protein complex, subunit gamma (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptin N terminal region;; Coatomer gamma subunit appendage platform subdomain;; HEAT repeats;; HEAT repeat;; HEAT-like repeat	Coatomer subunit gamma-1 GN=COPG1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit gamma-1 isoform X1 [Leptonychotes weddellii]
ENSG00000181790(ADGRB1)	--	0.718855118	70	0.506748472	56	0.499723189	50	0.331470502	38	0.675170813	78	0.224500027	26	0.476592694	-0.885396869	normal	0.920615372	0.446366501	normal	0.701599746	-0.912782349	normal	0.707950128	-0.331506492	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04596|0|hsa:575|BAI1, GDAIF, ADGRB1; brain-specific angiogenesis inhibitor 1; K04596 brain-specific angiogenesis inhibitor 1 (A)"	p53 signaling pathway (ko04115)	--	--	7 transmembrane receptor (Secretin family);; Thrombospondin type 1 domain;; Domain of unknown function (DUF3497);; Latrophilin/CL-1-like GPS domain;; Hormone receptor domain	Brain-specific angiogenesis inhibitor 1 (Precursor) GN=BAI1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	brain-specific angiogenesis inhibitor 1 precursor [Bos taurus] 
ENSG00000181804(SLC9A9)	--	0.894108319	37	0.882152145	19	0.285286272	13	0.614989187	26	1.4143719	39	0.897101965	38	0.963265584	-0.514238253	normal	0.795287429	0.961634415	normal	0.264286338	1.43732566	normal	0.429782446	0.556957921	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14725|0|pps:100971069|SLC9A9; solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9; K14725 solute carrier family 9 (sodium/hydrogen exchanger), member 9 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 9 GN=SLC9A9 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 9 [Oryctolagus cuniculus]
ENSG00000181817(LSM10)	--	28.4619	363	22.4295	293	28.0265	369	27.48514	366	27.0803	342	27.59774	357	0.968823911	-0.018878587	normal	0.944643362	0.200709494	normal	0.967665448	-0.055755855	normal	0.937817123	0.034197923	normal	[K]	Transcription	--	--	--	[A]	RNA processing and modification	LSM domain	U7 snRNA-associated Sm-like protein LSm10 GN=LSM10 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U7 snRNA-associated Sm-like protein LSm10 isoform X1 [Tupaia chinensis] 
ENSG00000181826(RELL1)	--	4.9785615	278	4.272889322	242	3.60651003	205	4.96444723	287	5.603536	300	4.278703253	236	0.967442277	0.01505172	normal	0.909459024	0.28691593	normal	0.949277435	0.19353984	normal	0.636377246	0.160852613	normal	--	--	--	--	--	--	--	Tumour necrosis factor receptor superfamily member 19	RELT-like protein 1 (Precursor) GN=RELL1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: RELT-like protein 1 isoform X1 [Camelus bactrianus] 
ENSG00000181827(RFX7)	--	7.54836513	1439	8.4894478	1580	7.615071	1405	7.8939883	1474	8.6922456	1647	8.55915696	1612	0.983731091	0.003833625	normal	0.983983482	0.03845339	normal	0.968652892	0.189799309	normal	0.750777125	0.076372136	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	RFX DNA-binding domain;; Poxvirus D5 protein-like	DNA-binding protein RFX7 GN=RFX7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-binding protein RFX7 [Oryctolagus cuniculus]
ENSG00000181830(SLC35C1)	--	11.166263	752	11.534819	789	11.656834	782	15.6387025	979	14.97393122	929	12.95116	861	0.832997124	0.349117274	normal	0.950921141	0.213848661	normal	0.969592256	0.130312938	normal	0.231601037	0.231822051	normal	--	--	--	"K15279|0|pps:100980689|SLC35C1; solute carrier family 35 (GDP-fucose transporter), member C1; K15279 solute carrier family 35 (GDP-fucose transporter), member C1 (A)"	--	[GOU]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Triose-phosphate Transporter family;; UAA transporter family;; EamA-like transporter family	GDP-fucose transporter 1 GN=SLC35C1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: GDP-fucose transporter 1 [Galeopterus variegatus]
ENSG00000181847(TIGIT)	--	0.020762939	1	0	0	0	0	0.020519993	1	0.172335989	0	0.041323646	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16350|0|ggo:101133621|TIGIT; T-cell immunoreceptor with Ig and ITIM domains; K16350 T-cell immunoreceptor with Ig and ITIM domains (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain	T-cell immunoreceptor with Ig and ITIM domains (Precursor) GN=TIGIT OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: T-cell immunoreceptor with Ig and ITIM domains [Galeopterus variegatus]
ENSG00000181852(RNF41)	--	11.27806996	659	12.72441857	686	12.22779681	673	13.94409081	889	15.16583146	836	15.52333174	918	0.715764013	0.400266663	normal	0.925231573	0.26334121	normal	0.589928895	0.438748799	normal	0.036184873	0.368121033	normal	--	--	Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: acid-amino acid ligase activity (GO:0016881);; Molecular Function: protein tag (GO:0031386);; Molecular Function: metal ion binding (GO:0046872);; 	"K11981|0|ptr:451989|RNF41; ring finger protein 41, E3 ubiquitin protein ligase; K11981 E3 ubiquitin-protein ligase NRDP1 [EC:6.3.2.19] (A)"	Endocytosis (ko04144)	[T]	Signal transduction mechanisms	"USP8 interacting;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc-finger of the MIZ type in Nse subunit;; U-box domain"	E3 ubiquitin-protein ligase NRDP1 GN=RNF41 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	E3 ubiquitin-protein ligase NRDP1 [Bos taurus] 
ENSG00000181856(SLC2A4)	--	0.627118674	29	0.190914603	6	0.150175	8	0.118796434	5	0.13509401	7	0.078888881	4	0.027357802	-2.250385289	normal	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K07191|0|hsa:6517|SLC2A4, GLUT4; solute carrier family 2 (facilitated glucose transporter), member 4; K07191 MFS transporter, SP family, solute carrier family 2 (facilitated glucose transporter), member 4 (A)"	FoxO signaling pathway (ko04068);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930)	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 4 GN=SLC2A4 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 4 isoform 2 [Ceratotherium simum simum]"
ENSG00000181873(IBA57)	--	1.40942	212	1.41623	217	1.32493	201	1.60554	241	1.86249	277	1.62665	244	0.956618143	0.15309552	normal	0.882907853	0.328732323	normal	0.924560267	0.269550836	normal	0.426227704	0.253238248	normal	[R]	General function prediction only	--	"K06980|0|hsa:200205|IBA57, C1orf69, MMDS3; IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae); K06980 (A)"	--	[K]	Transcription	Aminomethyltransferase folate-binding domain;; Glycine cleavage T-protein C-terminal barrel domain	"Putative transferase CAF17, mitochondrial (Precursor) GN=IBA57 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: putative transferase CAF17, mitochondrial [Camelus bactrianus]"
ENSG00000181885(CLDN7)	--	0.186737	3	0.536261	9	0.254243	2	0.4620574	5	0.7492334	11	0.323876	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06087|6.34587e-152|hsa:1366|CLDN7, CEPTRL2, CLDN-7, CPETRL2, Hs.84359, claudin-1; claudin 7; K06087 claudin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-7 GN=CLDN7 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: claudin-7 [Vicugna pacos] 
ENSG00000181894(ZNF329)	--	1.912513325	137	1.966432491	145	1.787261165	126	2.991123178	217	2.7821622	161	2.608675467	186	0.312714662	0.627055301	normal	0.960801774	0.128310853	normal	0.597171309	0.548140018	normal	0.172227103	0.445120544	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal"	Zinc finger protein 329 GN=ZNF329 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 329 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000181896(ZNF101)	--	2.046443606	147	2.444075	169	2.12588088	138	3.21484847	157	2.246656503	160	1.485396428	130	0.966571089	0.063474155	normal	0.962722911	-0.099463012	normal	0.965892945	-0.093393423	normal	0.946007535	-0.044367693	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100986332|ZNF101; zinc finger protein 101; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 101 GN=ZNF101 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 709-like [Orcinus orca]
ENSG00000181915(ADO)	--	15.6861	832	15.352	821	15.134	808	15.0218	805	17.4324	928	14.3039	765	0.974659606	-0.078280033	normal	0.966111758	0.155047274	normal	0.973611496	-0.087019578	normal	1	0.000245396	normal	--	--	"Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Biological Process: oxidation-reduction process (GO:0055114);; "	K10712|2.88395e-157|pps:100991144|ADO; 2-aminoethanethiol (cysteamine) dioxygenase; K10712 cysteamine dioxygenase [EC:1.13.11.19] (A)	Taurine and hypotaurine metabolism (ko00430)	[S]	Function unknown	Protein of unknown function (DUF1637)	2-aminoethanethiol dioxygenase GN=ADO OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: 2-aminoethanethiol dioxygenase [Physeter catodon]
ENSG00000181924(COA4)	--	72.70192	1135	69.64077	1068	82.310289	1300	72.41448	1169	74.274235	1165	66.50863	1051	0.981119851	0.011734717	normal	0.9762256	0.103850925	normal	0.892134342	-0.314632524	normal	0.780487663	-0.070598731	normal	--	--	--	"K18177|2.26114e-51|ptr:451415|COA4, CHCHD8; cytochrome c oxidase assembly factor 4 homolog (S. cerevisiae); K18177 cytochrome c oxidase assembly factor 4 (A)"	--	[R]	General function prediction only	CHCH domain	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial GN=COA4 OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	"PREDICTED: cytochrome c oxidase assembly factor 4 homolog, mitochondrial [Galeopterus variegatus] "
ENSG00000181938(GINS3)	--	10.617838	430	9.6420501	379	10.53024429	411	11.57087097	467	13.33387986	534	11.04806305	452	0.967070565	0.087952033	normal	0.53132389	0.471622907	normal	0.962270409	0.128442127	normal	0.342771923	0.231005839	normal	[S]	Function unknown	--	"K10734|0|hsa:64785|GINS3, PSF3; GINS complex subunit 3 (Psf3 homolog); K10734 GINS complex subunit 3 (A)"	--	[S]	Function unknown	GINS complex protein	DNA replication complex GINS protein PSF3 GN=GINS3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DNA replication complex GINS protein PSF3 isoform X1 [Eptesicus fuscus]
ENSG00000181982(CCDC149)	--	0.959226733	79	1.524594865	105	1.186880609	88	0.897385178	90	1.495067409	124	1.538554838	121	0.968017825	0.154424996	normal	0.953925613	0.215663364	normal	0.871252544	0.44459858	normal	0.56305018	0.280161146	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized coiled-coil protein (DUF2353)	Coiled-coil domain-containing protein 149 GN=CCDC149 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 149 isoform X1 [Bos taurus]
ENSG00000181991(MRPS11)	--	27.891538	1017	24.949903	945	26.134071	1030	27.557115	1122	26.961174	1074	25.788208	1079	0.975402908	0.110761388	normal	0.966959602	0.16293649	normal	0.978949682	0.05867491	normal	0.63570135	0.109170801	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02948|3.34237e-118|hsa:64963|MRPS11, HCC-2; mitochondrial ribosomal protein S11; K02948 small subunit ribosomal protein S11 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S11	"28S ribosomal protein S11, mitochondrial (Precursor) GN=MRPS11 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S11, mitochondrial isoform X1 [Vicugna pacos]"
ENSG00000182004(SNRPE)	--	65.23975247	691	72.6087584	778	75.76241612	796	95.67977647	1037	78.22294	810	83.41917438	885	0.159028215	0.553814665	normal	0.975792578	0.036655365	normal	0.967835602	0.144357372	normal	0.192609879	0.248790814	normal	[K]	Transcription	--	"K11097|6.47392e-51|ssc:100038330|SNRPE, Sm-E, SmE, snRNP-E; small nuclear ribonucleoprotein polypeptide E; K11097 small nuclear ribonucleoprotein E (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	Small nuclear ribonucleoprotein E GN=SNRPE OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	small nuclear ribonucleoprotein E [Sus scrofa] 
ENSG00000182010(RTKN2)	--	3.048653	132	2.19048427	171	3.150186836	169	3.7904262	178	2.858545849	152	2.397126158	125	0.861178587	0.396520139	normal	0.9521077	-0.189572092	normal	0.822110164	-0.438803307	normal	0.89145072	-0.075024355	normal	--	--	--	--	--	--	--	Cell division protein anillin;; PH domain	Rhotekin-2 GN=RTKN2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: rhotekin-2 [Galeopterus variegatus]
ENSG00000182013(PNMAL1)	--	10.267056	774	8.921013307	691	10.168377	767	11.42306	864	12.734157	954	8.513685	637	0.969782552	0.127625624	normal	0.588795597	0.443048547	normal	0.915040908	-0.275627408	normal	0.730104847	0.115583836	normal	--	--	--	--	--	--	--	PNMA	PNMA-like protein 1 GN=PNMAL1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: PNMA-like protein 1 [Odobenus rosmarus divergens]
ENSG00000182022(CHST15)	--	9.943867447	803	10.379303	684	11.355618	780	14.36066466	1047	13.03820298	973	10.046206	772	0.83071653	0.351367078	normal	0.419245713	0.48611155	normal	0.976462911	-0.023119661	normal	0.183951724	0.278580308	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K08106|0|hsa:51363|CHST15, BRAG, GALNAC4S-6ST; carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 (EC:2.8.2.33); K08106 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase [EC:2.8.2.33] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	--	--	Sulfotransferase domain;; Sulfotransferase family	Carbohydrate sulfotransferase 15 GN=CHST15 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carbohydrate sulfotransferase 15 [Tupaia chinensis]
ENSG00000182040(USH1G)	--	0.059519	4	0	0	0	0	0	0	0	0	0.0147412	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; SAM domain (Sterile alpha motif)	Usher syndrome type-1G protein GN=USH1G OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: Usher syndrome type-1G protein isoform X1 [Tupaia chinensis] 
ENSG00000182050(MGAT4C)	--	0.055257093	2	0.006216259	2	0.106699524	7	0.006042738	2	0.008833268	2	0.06566322	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K13748|0|ptr:467085|MGAT4C; MGAT4 family, member C; K13748 alpha-1,3-mannosylglycoprotein beta-1,4-N-acetylglucosaminyltransferase C [EC:2.4.1.201 2.4.1.145] (A)"	N-Glycan biosynthesis (ko00510)	--	--	N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region	"Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C GN=MGAT4C OS=Homo sapiens (Human) PE=2 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C [Loxodonta africana]"
ENSG00000182054(IDH2)	--	32.04040618	1338	23.23783669	981	25.11250553	1052	33.79900342	1423	34.11570516	1426	30.45390723	1276	0.982059583	0.057960742	normal	0.285923948	0.517557089	normal	0.930747223	0.269849443	normal	0.164628825	0.269629395	normal	[C]	Energy production and conversion	"Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00031|0|ptr:453645|IDH2; isocitrate dehydrogenase 2 (NADP+), mitochondrial; K00031 isocitrate dehydrogenase [EC:1.1.1.42] (A)"	Citrate cycle (TCA cycle) (ko00020);; Glutathione metabolism (ko00480);; Carbon metabolism (ko01200);; 2-Oxocarboxylic acid metabolism (ko01210);; Biosynthesis of amino acids (ko01230);; Peroxisome (ko04146)	[C]	Energy production and conversion	Isocitrate/isopropylmalate dehydrogenase	"Isocitrate dehydrogenase [NADP], mitochondrial (Precursor) GN=IDH2 OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: isocitrate dehydrogenase [NADP], mitochondrial [Oryctolagus cuniculus]"
ENSG00000182087(TMEM259)	--	61.73777421	2668	57.35917644	2567	55.20833146	2467	57.27862874	2513	56.51819206	2395	60.09252822	2471	0.985674371	-0.117110752	normal	0.984635386	-0.121410128	normal	0.988707971	-0.005950502	normal	0.72173641	-0.083160829	normal	--	--	--	--	--	[S]	Function unknown	Tumour-associated protein	Membralin GN=TMEM259 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: membralin isoform X1 [Sus scrofa]
ENSG00000182093(WRB)-2	--	33.31529417	645	27.2407747	531	25.49114024	500	34.12842868	665	32.783441	622	30.0882838	591	0.974560682	0.013191969	normal	0.947043459	0.206233025	normal	0.936771765	0.232291664	normal	0.57046325	0.142385285	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000182095(TNRC18)	--	35.782437	5943	32.3853692	6316	32.1848608	6078	28.03382128	4664	24.99928709	4697	38.21655832	7170	0.885110042	-0.380344541	normal	0.7282669	-0.448573088	normal	0.984126193	0.23003225	normal	0.653249262	-0.169517244	normal	--	--	Molecular Function: chromatin binding (GO:0003682);; 	--	--	--	--	BAH domain	Trinucleotide repeat-containing gene 18 protein GN=TNRC18 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: trinucleotide repeat-containing gene 18 protein [Orcinus orca]
ENSG00000182103(FAM181B)	--	0.0832142	5	0.257333	16	0	0	0.0490782	3	0	0	0.0328429	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM181	Protein FAM181B GN=FAM181B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM181B [Odobenus rosmarus divergens]
ENSG00000182107(TMEM30B)	--	0.316935	21	0.434138	29	0.324869	21	0.19359	13	0.391444	26	0.178188	12	0.977089228	-0.660736649	normal	0.983537351	-0.169620962	normal	0.971898459	-0.743989693	normal	0.551378432	-0.498664236	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[DKT]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Signal transduction mechanisms"	LEM3 (ligand-effect modulator 3) family / CDC50 family	Cell cycle control protein 50B GN=TMEM30B OS=Homo sapiens (Human) PE=1 SV=1	DKT	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Signal transduction mechanisms"	PREDICTED: cell cycle control protein 50B [Sus scrofa]
ENSG00000182108(DEXI)	--	20.515698	508	21.56785	547	22.30736	570	22.455411	565	22.00961	546	18.73253	469	0.965135862	0.122239446	normal	0.971752436	-0.024000027	normal	0.901567151	-0.288819264	normal	0.8458954	-0.062104068	normal	--	--	--	--	--	--	--	Dexamethasone-induced	Dexamethasone-induced protein GN=DEXI OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: dexamethasone-induced protein [Chrysochloris asiatica]
ENSG00000182117(NOP10)	--	308.39992	1925	329.70405	2091	297.62038	1919	312.536677	2052	304.665124	1906	332.089823	2141	0.985811179	0.061292637	normal	0.978766622	-0.154954066	normal	0.979898796	0.149527033	normal	0.955870285	0.018129124	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K11130|6.56132e-41|rno:691534|Nop10, Nola3; NOP10 ribonucleoprotein; K11130 H/ACA ribonucleoprotein complex subunit 3 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	"Nucleolar RNA-binding protein, Nop10p family"	H/ACA ribonucleoprotein complex subunit 3 GN=NOP10 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: H/ACA ribonucleoprotein complex subunit 3 [Oryctolagus cuniculus] 
ENSG00000182118(FAM89A)	--	12.5843	257	9.59637	204	10.5637	224	10.7857	224	11.0848	226	9.86609	203	0.939074954	-0.227642688	normal	0.959243931	0.125443295	normal	0.957476329	-0.149251502	normal	0.832826563	-0.090474026	normal	--	--	--	--	--	--	--	--	Protein FAM89A GN=FAM89A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: protein FAM89A, partial [Equus przewalskii]"
ENSG00000182134(TDRKH)	--	8.6306438	532	9.30072418	575	9.477792453	579	6.631045201	383	6.046326	364	7.188633676	442	0.398518456	-0.503192723	normal	0.030167201	-0.678785578	normal	0.738428504	-0.396619035	normal	0.005534899	-0.524581345	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	"K18406|0|hsa:11022|TDRKH, TDRD2; tudor and KH domain containing; K18406 tudor domain-containing protein 2 (A)"	--	[T]	Signal transduction mechanisms	KH domain;; Tudor domain;; KH domain;; KH domain	Tudor and KH domain-containing protein GN=TDRKH OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tudor and KH domain-containing protein isoform 1 [Equus caballus] 
ENSG00000182141(ZNF708)	--	1.061174816	63	0.940485377	73	1.39527231	73	1.308020109	98	1.3100153	75	1.2176737	92	0.774309787	0.594883214	normal	0.97277787	0.017215723	normal	0.946542551	0.319537333	normal	0.541679846	0.321082898	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101141027|ZNF708; zinc finger protein 708 isoform 1; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; C1-like domain;; DNA directed RNA polymerase, 7 kDa subunit;; CHY zinc finger;; Rad4 beta-hairpin domain 1;; TFIIH C1-like domain;; Desulfoferrodoxin, N-terminal domain"	Zinc finger protein 708 GN=ZNF708 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	TPA: repressor transcriptional factor-like [Bos taurus]
ENSG00000182149(IST1)	--	84.35008485	3612	87.81974106	3620	77.47833115	3359	99.0453809	3806	103.4388294	4201	92.13657618	3808	0.991350726	0.044626912	normal	0.982740073	0.193241538	normal	0.984318097	0.172637199	normal	0.511604827	0.136516838	normal	--	--	Biological Process: protein transport (GO:0015031);; 	--	--	[Z]	Cytoskeleton	Regulator of Vps4 activity in the MVB pathway	IST1 homolog GN=IST1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: IST1 homolog isoform X1 [Echinops telfairi]
ENSG00000182150(ERCC6L2)	--	5.331989599	622	5.520971	597	4.566106146	538	4.01725899	491	4.614108416	549	4.855063839	536	0.790641477	-0.370989574	normal	0.962397231	-0.141976159	normal	0.972491291	-0.01362624	normal	0.4626528	-0.177945394	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[KL]	"Transcription;; Replication, recombination and repair"	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase;; Class II histone deacetylase complex subunits 2 and 3;; Type III restriction enzyme, res subunit"	DNA excision repair protein ERCC-6-like 2 GN=ERCC6L2 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: putative DNA repair and recombination protein RAD26 isoform X1 [Vicugna pacos]
ENSG00000182154(MRPL41)	--	76.6612	1286	69.8888	1217	70.9943	1274	77.4305	1338	78.6706	1337	77.4449	1340	0.982384644	0.026324377	normal	0.977092759	0.114108425	normal	0.981210031	0.064501618	normal	0.79004013	0.067021944	normal	--	--	--	K17422|1.3672e-84|ptr:737212|MRPL41; mitochondrial ribosomal protein L41; K17422 large subunit ribosomal protein L41 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal protein L27	"39S ribosomal protein L41, mitochondrial (Precursor) GN=MRPL41 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L41, mitochondrial [Tupaia chinensis] "
ENSG00000182158(CREB3L2)	--	12.4646245	1511	12.95288576	1583	14.02618965	1650	19.11040379	2386	20.1997498	2549	20.25291641	2603	0.03113102	0.627746155	normal	0.015537303	0.665338222	normal	0.018713172	0.648940301	normal	3.71E-06	0.647274882	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09048|0|ptr:738928|CREB3L2; cAMP responsive element binding protein 3-like 2; K09048 cyclic AMP-responsive element-binding protein 3 (A)	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; TNF signaling pathway (ko04668);; Cholinergic synapse (ko04725);; Dopaminergic synapse (ko04728);; Insulin secretion (ko04911);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203);; Prostate cancer (ko05215)	--	--	bZIP transcription factor;; Basic region leucine zipper;; bZIP Maf transcription factor	Processed cyclic AMP-responsive element-binding protein 3-like protein 2 GN=CREB3L2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: cAMP responsive element binding protein 3-like 2 [Canis lupus familiaris]
ENSG00000182162(P2RY8)	--	0.035559084	3	0.011687786	1	0	0	0	0	0.011524474	0	0.011772969	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08386|0|hsa:286530|P2RY8, P2Y8; purinergic receptor P2Y, G-protein coupled, 8; K08386 purinergic receptor P2Y, G protein-coupled, 8 (A)"	Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family)	P2Y purinoceptor 8 GN=P2RY8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: P2Y purinoceptor 8 [Galeopterus variegatus]
ENSG00000182168(UNC5C)	--	0.157779365	26	0.22485107	37	0.097022774	15	0.169560429	28	0.211899375	36	0.126525229	21	0.986086942	0.071983592	normal	0.981400607	-0.058529563	normal	0.984457445	0.439539399	normal	0.93492335	0.101027162	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K07521|0|pps:100993093|UNC5C; unc-5 homolog C (C. elegans); K07521 netrin receptor unc-5 (A)	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	ZU5 domain;; Death domain;; Immunoglobulin I-set domain;; Thrombospondin type 1 domain;; Immunoglobulin domain	Netrin receptor UNC5C (Precursor) GN=UNC5C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: netrin receptor UNC5C isoform X2 [Chrysochloris asiatica]
ENSG00000182173(TSEN54)	--	15.027563	551	13.6529137	525	16.625402	618	16.348559	607	16.212658	578	14.65706365	522	0.967686549	0.108523559	normal	0.965518291	0.11700422	normal	0.927844846	-0.251178844	normal	0.983948554	-0.010336861	normal	--	--	--	"K15326|0|hsa:283989|TSEN54, PCH2A, PCH4, SEN54L, sen54; TSEN54 tRNA splicing endonuclease subunit; K15326 tRNA-splicing endonuclease subunit Sen54 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	tRNA-splicing endonuclease subunit sen54 N-term	tRNA-splicing endonuclease subunit Sen54 GN=TSEN54 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-splicing endonuclease subunit Sen54 [Pteropus alecto]
ENSG00000182175(RGMA)	--	0.016824504	2	0.033866132	2	0.064291677	9	0.153492352	10	0.032850124	1	0.217281505	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06847|0|hsa:56963|RGMA, RGM; repulsive guidance molecule family member a; K06847 RGM domain family (A)"	--	--	--	Repulsive guidance molecule (RGM) C-terminus;; Repulsive guidance molecule (RGM) N-terminus	Repulsive guidance molecule A (Precursor) GN=RGMA OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: repulsive guidance molecule A [Ceratotherium simum simum]
ENSG00000182177(ASB18)	--	0	0	0.112988032	2	0.053588862	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K10340|0|hsa:401036|ASB18, ASB-18; ankyrin repeat and SOCS box containing 18; K10340 ankyrin repeat and SOCS box protein 18 (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SOCS box	Ankyrin repeat and SOCS box protein 18 GN=ASB18 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 18 [Tursiops truncatus]
ENSG00000182179(UBA7)	--	0.058700431	4	0.202393535	14	0.132215754	8	0.280199361	19	0.502481722	34	0.364444624	25	--	--	--	0.689502969	1.174981088	normal	0.676904938	1.471401081	normal	--	--	--	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	"K10698|0|hsa:7318|UBA7, D8, UBA1B, UBE1L, UBE2; ubiquitin-like modifier activating enzyme 7; K10698 ubiquitin-activating enzyme E1-like [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	ThiF family;; Repeat in ubiquitin-activating (UBA) protein;; Ubiquitin-activating enzyme e1 C-terminal domain;; Ubiquitin-activating enzyme active site	Ubiquitin-like modifier-activating enzyme 7 GN=UBA7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like modifier-activating enzyme 7 [Ceratotherium simum simum]
ENSG00000182180(MRPS16)	--	109.4729702	3553	106.6022101	3631	104.2797905	3661	105.47583	3754	94.06882558	3628	88.96781002	3305	0.99118375	0.048538278	normal	0.991199683	-0.022609612	normal	0.985690813	-0.155811171	normal	0.877071809	-0.042699476	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02959|5.89744e-87|ptr:450894|MRPS16; mitochondrial ribosomal protein S16; K02959 small subunit ribosomal protein S16 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S16	"28S ribosomal protein S16, mitochondrial (Precursor) GN=MRPS16 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S16, mitochondrial isoform X2 [Tupaia chinensis]"
ENSG00000182185(RAD51B)	--	6.392102386	123	6.348735485	92	5.595300955	110	5.49303395	119	5.434493046	109	7.528518876	152	0.967714452	-0.077544139	normal	0.956245384	0.219872228	normal	0.825901619	0.452957066	normal	0.675169034	0.205168249	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA helicase activity (GO:0003678);; Molecular Function: single-stranded DNA binding (GO:0003697);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication (GO:0006260);; Biological Process: DNA repair (GO:0006281);; 	"K10869|0|hsa:5890|RAD51B, R51H2, RAD51L1, REC2; RAD51 paralog B; K10869 RAD51-like protein 1 (A)"	Homologous recombination (ko03440)	[L]	"Replication, recombination and repair"	Rad51;; AAA domain;; KaiC;; DnaB-like helicase C terminal domain;; recA bacterial DNA recombination protein	DNA repair protein RAD51 homolog 2 GN=RAD51B OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	"DNA repair protein RAD51-like protein 2, partial [Bos mutus]"
ENSG00000182195(LDOC1)	--	62.718	1344	52.4338	1120	58.1046	1261	51.5844	1108	48.0998	1032	48.4472	1050	0.899315705	-0.309017717	normal	0.971779977	-0.139286321	normal	0.929056364	-0.272112234	normal	0.172227103	-0.244977583	normal	--	--	--	--	--	--	--	--	Protein LDOC1 GN=LDOC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein LDOC1 [Camelus dromedarius]
ENSG00000182197(EXT1)	--	36.58718971	2146	33.78946321	2050	30.18163591	2008	47.56273866	2877	42.53159412	2468	38.22365332	2475	0.800680065	0.391839851	normal	0.960910823	0.246126252	normal	0.935959057	0.293178589	normal	0.051314941	0.312206185	normal	--	--	"Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K02366|0|hsa:2131|EXT1, EXT, LGCR, LGS, TRPS2, TTV; exostosin glycosyltransferase 1 (EC:2.4.1.225 2.4.1.224); K02366 glucuronyl/N-acetylglucosaminyl transferase EXT1 [EC:2.4.1.224 2.4.1.225] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[GMW]	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Extracellular structures	Glycosyl transferase family 64 domain;; Exostosin family	Exostosin-1 GN=EXT1 OS=Homo sapiens (Human) PE=1 SV=2	GMW	Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Extracellular structures	PREDICTED: exostosin-1 isoform X1 [Galeopterus variegatus]
ENSG00000182199(SHMT2)	--	56.66279478	1913	49.57297415	1533	56.54628758	1874	76.45461274	2486	81.38237777	2578	74.40589901	2413	0.878983917	0.346912163	normal	0.003040238	0.727908401	normal	0.863254797	0.356161588	normal	0.001371425	0.469982257	normal	[E]	Amino acid transport and metabolism	--	"K00600|0|ggo:101134424|SHMT2; serine hydroxymethyltransferase, mitochondrial isoform 1; K00600 glycine hydroxymethyltransferase [EC:2.1.2.1] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Cyanoamino acid metabolism (ko00460);; Glyoxylate and dicarboxylate metabolism (ko00630);; One carbon pool by folate (ko00670);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Serine hydroxymethyltransferase	"Serine hydroxymethyltransferase, mitochondrial (Precursor) GN=SHMT2 OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: serine hydroxymethyltransferase, mitochondrial isoformX1 [Equus caballus]"
ENSG00000182208(MOB2)	--	16.91612437	373	16.35569279	384	19.184958	429	19.77379876	430	18.25903127	409	19.87854898	441	0.953221717	0.173662142	normal	0.966637813	0.069303494	normal	0.97008113	0.03140039	normal	0.786500082	0.089125877	normal	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Mob1/phocein family	MOB kinase activator 2 GN=MOB2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: MOB kinase activator 2 [Tupaia chinensis]
ENSG00000182218(HHIPL1)	--	0.079825	7	0.0135449	2	0.0133588	1	0.0525785	5	0.1027746	8	0.048240035	7	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Glucose / Sorbosone dehydrogenase;; Scavenger receptor cysteine-rich domain;; Folate receptor family	HHIP-like protein 1 (Precursor) GN=HHIPL1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: HHIP-like protein 1 [Mustela putorius furo]
ENSG00000182220(ATP6AP2)	--	92.09513972	2777	83.00495865	2530	78.715541	2419	93.495734	2875	91.16497459	2761	100.3104193	3062	0.989712064	0.01919208	normal	0.986350639	0.104567101	normal	0.910567348	0.331587414	normal	0.453393299	0.14979609	normal	--	--	Molecular Function: receptor activity (GO:0004872);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[C]	Energy production and conversion	Renin receptor-like protein	Renin receptor (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: renin receptor [Galeopterus variegatus]
ENSG00000182223(ZAR1)	--	0.0513039	1	0	0	0.0466329	0	0.0493202	1	0.195174	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18762|0|hsa:326340|ZAR1, Z3CXXC6; zygote arrest 1; K18762 zygote arrest protein 1 (A)"	--	--	--	Zinc-binding domain	Zygote arrest protein 1 GN=ZAR1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: zygote arrest protein 1 [Odobenus rosmarus divergens]
ENSG00000182224(CYB5D1)	--	8.94605	575	9.87808	643	10.85292	697	12.11065	786	11.18937	716	9.41398	610	0.661213286	0.419173752	normal	0.965942425	0.133416834	normal	0.951253309	-0.20017622	normal	0.634286763	0.119553894	normal	--	--	--	--	--	[C]	Energy production and conversion	Cytochrome b5-like Heme/Steroid binding domain	Cytochrome b5 domain-containing protein 1 GN=CYB5D1 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: cytochrome b5 domain-containing protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000182230(FAM153B)	--	0.309198034	2	0.367108772	16	0.250581096	4	0.146202039	1	0.097229082	3	0.093826904	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM153B GN=FAM153B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000182240(BACE2)	--	17.4080952	1010	14.64993582	840	15.2142161	901	16.9891047	1029	16.28282604	931	16.98792883	999	0.97976636	-0.003938638	normal	0.970570988	0.126748466	normal	0.970224576	0.140442177	normal	0.737184545	0.083826236	normal	--	--	--	"K07747|0|hsa:25825|BACE2, AEPLC, ALP56, ASP1, ASP21, BAE2, CEAP1, DRAP; beta-site APP-cleaving enzyme 2 (EC:3.4.23.45); K07747 beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:3.4.23.45] (A)"	Alzheimer's disease (ko05010)	[O]	"Posttranslational modification, protein turnover, chaperones"	Eukaryotic aspartyl protease;; Xylanase inhibitor C-terminal	Beta-secretase 2 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: beta-secretase 2 [Equus caballus]
ENSG00000182247(UBE2E2)	--	55.2446944	782	32.03137139	728	54.55353241	705	42.931705	614	53.8472896	698	30.2282747	510	0.770324478	-0.378919639	normal	0.972147663	-0.081964067	normal	0.470497566	-0.474216066	normal	0.117398122	-0.303485985	normal	--	--	--	K06689|2.83835e-105|cge:100766861|Ube2e2; ubiquitin-conjugating enzyme E2E 2; K06689 ubiquitin-conjugating enzyme E2 D/E [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 E2 GN=UBE2E2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 E2 [Erinaceus europaeus]
ENSG00000182253(SYNM)	--	19.492592	2734	29.207569	4431	21.7260547	3401	15.941704	2304	14.2454441	2204	18.073815	2556	0.949402066	-0.277534633	normal	1.18E-07	-1.028426388	down	0.735057546	-0.420146348	normal	0.07209531	-0.601970765	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K10376|0|ptr:467773|SYNM, DMN; synemin, intermediate filament protein; K10376 desmuslin (A)"	--	--	--	Intermediate filament protein	Synemin GN=SYNM OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: synemin isoform 1 [Ceratotherium simum simum]
ENSG00000182256(GABRG3)	--	0.584114276	11	0.169194999	3	0.964521897	17	0	0	0.107851693	1	0.148655555	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05186|0|nle:100596679|GABRG3; gamma-aminobutyric acid (GABA) A receptor, gamma 3; K05186 gmma-aminobutyric acid receptor subunit gamma (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Gamma-aminobutyric acid receptor subunit gamma-3 (Precursor) GN=GABRG3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit gamma-3 [Orcinus orca]
ENSG00000182257(PRR34)	--	0.125566	7	0.088976	5	0.0698988	3	0.0361387	2	0.0698589	3	0.035547	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Proline-rich protein 34 GN=PRR34 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized protein C22orf26 homolog [Elephantulus edwardii]
ENSG00000182263(FIGN)	--	2.651073501	401	3.180845022	472	3.877131361	569	1.418808469	214	1.396089571	210	1.811723731	274	0.000288887	-0.931850999	normal	2.56E-07	-1.183976124	down	2.47E-06	-1.058398991	down	1.43E-05	-1.066779347	down	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily)	Fidgetin GN=FIGN OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: fidgetin isoform X2 [Equus przewalskii]
ENSG00000182272(B4GALNT4)	--	14.67622	969	9.4426	641	10.03041	696	9.09854	605	11.7756	782	6.39787	428	0.006546242	-0.708956831	normal	0.923010543	0.26485119	normal	0.010819029	-0.707787083	normal	0.457854539	-0.367447414	normal	--	--	Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: Golgi cisterna membrane (GO:0032580);; 	"K09657|0|hsa:338707|B4GALNT4; beta-1,4-N-acetyl-galactosaminyl transferase 4 (EC:2.4.1.244); K09657 beta-1,4-N-acetylgalactosaminyltransferase 4 [EC:2.4.1.244] (A)"	--	[G]	Carbohydrate transport and metabolism	Chondroitin N-acetylgalactosaminyltransferase;; PA14 domain;; N-terminal domain of galactosyltransferase	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 GN=B4GALNT4 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1 [Ceratotherium simum simum]
ENSG00000182287(AP1S2)	--	14.80296257	455	14.0060923	426	17.45796741	531	24.40385999	759	17.63471279	545	13.74302196	429	0.010217766	0.705538067	normal	0.857526661	0.332929029	normal	0.877092081	-0.315025505	normal	0.555432618	0.272915244	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	"K12394|6.7264e-113|pps:100983447|AP1S2; adaptor-related protein complex 1, sigma 2 subunit; K12394 AP-1 complex subunit sigma 1/2 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Clathrin adaptor complex small chain	AP-1 complex subunit sigma-2 GN=AP1S2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-1 complex subunit sigma-2 isoform X2 [Vicugna pacos]
ENSG00000182307(C8orf33)	--	25.9924	1202	28.4108	1334	23.2362	1082	34.224	1597	36.4506	1679	28.4587	1318	0.791048655	0.37867403	normal	0.908560079	0.310103055	normal	0.927461557	0.276008366	normal	0.07626606	0.322590138	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4615)	UPF0488 protein C8orf33 GN=C8orf33 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0488 protein C8orf33 homolog [Trichechus manatus latirostris]
ENSG00000182308(DCAF4L1)	--	0.0994028	8	0.171613	14	0.147499	11	0.171692	14	0.168269	13	0.295284	24	--	--	--	--	--	--	0.924218451	1.020302065	normal	--	--	--	--	--	--	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 4-like protein 1 GN=DCAF4L1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 4 isoform X5 [Vicugna pacos]
ENSG00000182310(SPACA6)	--	5.274337	241	2.822553589	200	3.068483936	154	2.199433849	121	1.899262029	149	1.808105249	140	0.000584265	-1.015531767	down	0.78505368	-0.442225055	normal	0.96094725	-0.144308071	normal	0.072826928	-0.558514798	normal	--	--	--	--	--	--	--	Immunoglobulin domain	--	S	Function unknown	PREDICTED: uncharacterized protein LOC103554203 isoform X2 [Equus przewalskii]
ENSG00000182318(ZSCAN22)	--	1.57681	139	1.39542	123	1.30715	115	1.33024	116	1.48084	129	1.87178	165	0.936221207	-0.288298284	normal	0.96699851	0.046725214	normal	0.728534543	0.506946548	normal	0.856751286	0.100726953	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:342945|ZSCAN22, HKR2, ZNF50; zinc finger and SCAN domain containing 22; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger and SCAN domain-containing protein 22 GN=ZSCAN22 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger and SCAN domain-containing protein 22 [Ursus maritimus] 
ENSG00000182325(FBXL6)	--	13.1430191	406	10.863539	356	11.554834	373	12.032897	377	13.634828	418	10.522434	344	0.960064531	-0.137208438	normal	0.942413742	0.209377617	normal	0.961459212	-0.124532591	normal	0.974200785	-0.016309441	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10272|0|hsa:26233|FBXL6, FBL6, FBL6A, PP14630; F-box and leucine-rich repeat protein 6; K10272 F-box and leucine-rich repeat protein 6 (A)"	--	[R]	General function prediction only	F-box-like;; F-box domain	F-box/LRR-repeat protein 6 GN=FBXL6 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: F-box/LRR-repeat protein 6 [Bubalus bubalis]
ENSG00000182326(C1S)	--	11.16374765	664	11.18668884	669	8.976620014	538	39.29137196	2364	46.09857929	2722	64.32286	3832	0	1.798791096	up	0	2.00073625	up	0	2.820660893	up	1.62E-07	2.232800949	up	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: proteolysis (GO:0006508);; 	"K01331|0|hsa:716|C1S; complement component 1, s subcomponent (EC:3.4.21.42); K01331 complement component 1, s subcomponent [EC:3.4.21.42] (A)"	Complement and coagulation cascades (ko04610);; Pertussis (ko05133);; Staphylococcus aureus infection (ko05150);; Systemic lupus erythematosus (ko05322)	[E]	Amino acid transport and metabolism	Trypsin;; CUB domain;; Sushi domain (SCR repeat);; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain;; CUB-like domain	Complement C1s subcomponent light chain (Precursor) GN=C1S OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: complement C1s subcomponent isoform 1 [Odobenus rosmarus divergens] 
ENSG00000182327(GLTPD2)	--	2.18341	28	1.16762	16	1.28157	17	0.830453	11	0.675185	8	0.684928	9	0.750737149	-1.264507612	normal	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: cytoplasm (GO:0005737);; Molecular Function: glycolipid transporter activity (GO:0017089);; Biological Process: glycolipid transport (GO:0046836);; Molecular Function: glycolipid binding (GO:0051861);; 	--	--	--	--	Glycolipid transfer protein (GLTP)	Glycolipid transfer protein domain-containing protein 2 GN=GLTPD2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: glycolipid transfer protein domain-containing protein 2 isoform X1 [Equus caballus]
ENSG00000182329(KIAA2012)	--	0.04819109	5	0.009968092	1	0.091171904	9	0.01988519	2	0.061607911	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Uncharacterized protein KIAA2012 {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein KIAA2012 homolog [Vicugna pacos]
ENSG00000182359(KBTBD3)	--	1.603154	66	1.222781142	56	1.413773	56	1.2997867	57	0.974632	39	0.625103348	35	0.968127537	-0.236407932	normal	0.92676035	-0.526255619	normal	0.87406218	-0.663498875	normal	0.421119935	-0.465230548	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10471|0|ptr:451523|KBTBD3; kelch repeat and BTB (POZ) domain containing 3; K10471 kelch repeat and BTB domain-containing protein 3 (A)	--	--	--	"BTB And C-terminal Kelch;; BTB/POZ domain;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain"	Kelch repeat and BTB domain-containing protein 3 GN=KBTBD3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch repeat and BTB domain-containing protein 3 isoform X2 [Oryctolagus cuniculus]
ENSG00000182362(YBEY)	--	22.971529	231	22.9932	230	20.79463418	216	17.51774101	185	20.513072	209	21.096143	217	0.87674537	-0.348602695	normal	0.954661516	-0.158463936	normal	0.966993318	-0.001616421	normal	0.649305813	-0.168782532	normal	[R]	General function prediction only	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: rRNA processing (GO:0006364);; 	--	--	--	--	Uncharacterized protein family UPF0054	Putative ribonuclease GN=YBEY OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: putative ribonuclease isoform X1 [Equus caballus] 
ENSG00000182372(CLN8)	--	8.284108367	535	12.06190814	769	8.378434403	551	13.61769962	766	10.17366339	753	14.709165	840	0.417352753	0.485801798	normal	0.974732345	-0.051657627	normal	0.081334659	0.598705143	normal	0.172227103	0.325455842	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K12360|0|hsa:2055|CLN8, C8orf61, EPMR; ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation); K12360 ceroid-lipofuscinosis neuronal protein 8 (A)"	--	[TR]	Signal transduction mechanisms;; General function prediction only	TLC domain	Protein CLN8 GN=CLN8 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein CLN8 [Galeopterus variegatus]
ENSG00000182378(PLCXD1)	--	71.33206465	4770	71.7520483	4813	71.2704112	4719	35.21837662	1939	28.52408021	1791	30.58176156	2111	6.65E-14	-1.328813442	down	5.55E-16	-1.446820804	down	1.62E-10	-1.168270848	down	5.14E-23	-1.312933199	down	--	--	--	--	--	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain"	PI-PLC X domain-containing protein 1 GN=PLCXD1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: PI-PLC X domain-containing protein 1 [Odobenus rosmarus divergens]
ENSG00000182379(NXPH4)	--	4.197438	106	4.11455	103	3.753086	99	3.385023	85	4.481616	114	2.909506304	77	0.932766047	-0.343784119	normal	0.964843078	0.123242469	normal	0.930599665	-0.364530724	normal	0.745796906	-0.179623567	normal	--	--	--	--	--	--	--	Neurexophilin	Neurexophilin-4 (Precursor) GN=NXPH4 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: neurexophilin-4 [Pteropus alecto]
ENSG00000182389(CACNB4)	--	0.226055045	18	0.115819522	8	0.87594732	12	0.174209339	11	0.118578601	7	0.14242294	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: voltage-gated calcium channel activity (GO:0005245);; Cellular Component: voltage-gated calcium channel complex (GO:0005891);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04865|0|pps:100976785|CACNB4; calcium channel, voltage-dependent, beta 4 subunit; K04865 voltage-dependent calcium channel beta-4 (A)"	MAPK signaling pathway (ko04010);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Oxytocin signaling pathway (ko04921);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Guanylate kinase;; Voltage gated calcium channel subunit beta domain 4Aa N terminal	Voltage-dependent L-type calcium channel subunit beta-4 GN=CACNB4 OS=Homo sapiens (Human) PE=1 SV=2	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: voltage-dependent L-type calcium channel subunit beta-4 isoform 1 [Ceratotherium simum simum]
ENSG00000182400(TRAPPC6B)	--	8.20285302	365	7.541659	360	7.416824164	347	7.473129	358	6.596640445	312	8.99534	427	0.967390913	-0.058520397	normal	0.936036105	-0.226852761	normal	0.901888527	0.289868229	normal	0.983948554	0.012466287	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Transport protein particle (TRAPP) component	Trafficking protein particle complex subunit 6B GN=TRAPPC6B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	trafficking protein particle complex subunit 6B [Bos taurus] 
ENSG00000182405(PGBD4)	--	2.42739	275	2.02539	227	2.41541	269	1.88017	213	1.70452	193	1.85263	210	0.804788383	-0.396883034	normal	0.930920074	-0.253682814	normal	0.851937883	-0.363191273	normal	0.233602767	-0.344910012	normal	--	--	--	--	--	--	--	Transposase IS4;; DDE_Tnp_1-like zinc-ribbon	PiggyBac transposable element-derived protein 4 GN=PGBD4 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: piggyBac transposable element-derived protein 4-like [Orycteropus afer afer]
ENSG00000182446(NPLOC4)	--	65.33170762	5366	63.72882604	5264	63.20607743	5343	70.75926317	5742	81.04426853	6146	67.34017371	5487	0.993374829	0.066855506	normal	0.986054901	0.202007968	normal	0.993696535	0.030067718	normal	0.667150588	0.10011768	normal	--	--	--	"K14015|0|hsa:55666|NPLOC4, NPL4; nuclear protein localization 4 homolog (S. cerevisiae); K14015 nuclear protein localization protein 4 homolog (A)"	Protein processing in endoplasmic reticulum (ko04141)	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	"NPL4 family;; NPL4 family, putative zinc binding region;; Nuclear pore localisation protein NPL4"	Nuclear protein localization protein 4 homolog GN=NPLOC4 OS=Homo sapiens (Human) PE=1 SV=3	UY	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	PREDICTED: nuclear protein localization protein 4 homolog isoform X2 [Equus przewalskii]
ENSG00000182450(KCNK4)	--	0.082392285	2	0.186571694	5	0.182303076	4	0.08947917	2	0	0	0.10144488	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04915|0|pon:100452369|KCNK4; potassium channel, subfamily K, member 4; K04915 potassium channel subfamily K member 4 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel;; Ion transport protein	Potassium channel subfamily K member 4 GN=KCNK4 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel subfamily K member 4 isoform X1 [Galeopterus variegatus]
ENSG00000182459(TEX19)	--	0.103338	4	0.0756657	3	0.0997913	3	0.0515526	2	0.177522	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testis-expressed protein 19	Testis-expressed sequence 19 protein GN=TEX19 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 19 protein [Lipotes vexillifer]
ENSG00000182463(TSHZ2)	--	0	0	0	0	0	0	0.009174631	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K09236|0|ptr:458344|TSHZ2; teashirt zinc finger homeobox 2; K09236 teashirt (A)	--	--	--	C2H2 type zinc-finger (2 copies);; C2H2-type zinc finger	Teashirt homolog 2 GN=TSHZ2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: teashirt homolog 2 [Equus przewalskii] 
ENSG00000182472(CAPN12)	--	18.485312	234	16.07799299	197	17.2838119	220	21.24334817	262	18.6805819	222	14.1090961	175	0.959461134	0.131410332	normal	0.956188096	0.149853374	normal	0.890669667	-0.33584573	normal	1	-0.004693473	normal	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	K04740|0|hsa:147968|CAPN12; calpain 12; K04740 calpain-12 [EC:3.4.22.-] (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III"	Calpain-12 GN=CAPN12 OS=Homo sapiens (Human) PE=2 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-12 [Sus scrofa]
ENSG00000182473(EXOC7)	--	30.8865238	2973	32.45308243	3191	29.22724937	2955	30.58350665	3080	32.32894848	3201	29.8949776	3040	0.990220343	0.020168384	normal	0.99035504	-0.016904491	normal	0.990006872	0.032605299	normal	0.976471761	0.010317975	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: exocytosis (GO:0006887);; 	K07195|0|mcf:101865185|uncharacterized LOC101865185; K07195 exocyst complex component 7 (A)	Insulin signaling pathway (ko04910)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exo70 exocyst complex subunit	Exocyst complex component 7 GN=EXOC7 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 7 isoformX2 [Equus caballus]
ENSG00000182481(KPNA2)	--	279.936836	10581	278.2651345	10520	281.64388	10574	289.4201586	11059	278.1720085	10490	229.2488441	8714	0.996430121	0.032908018	normal	0.996209485	-0.025542907	normal	0.978062194	-0.287360309	normal	0.734432459	-0.087649662	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein import into nucleus (GO:0006606);; Molecular Function: protein transporter activity (GO:0008565);; 	"K15043|0|hsa:3838|KPNA2, IPOA1, QIP2, RCH1, SRP1alpha; karyopherin alpha 2 (RAG cohort 1, importin alpha 1); K15043 importin subunit alpha-2 (A)"	Influenza A (ko05164)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Armadillo/beta-catenin-like repeat;; Importin beta binding domain;; HEAT repeats;; HEAT-like repeat;; HEAT repeat;; Armadillo-like	Importin subunit alpha-1 GN=KPNA2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin subunit alpha-2 [Ceratotherium simum simum]
ENSG00000182489(XKRX)	--	0.064923186	3	0.028326954	1	0.085571653	3	0.107569545	5	0.126150306	5	0.128899329	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	XK-related protein	XK-related protein 2 GN=XKRX OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: XK-related protein 2 [Erinaceus europaeus]
ENSG00000182492(BGN)	--	0.0233447	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K08118|0|hsa:633|BGN, DSPG1, PG-S1, PGI, SLRR1A; biglycan; K08118 biglycan (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat N-terminal domain;; Leucine-rich repeat;; Leucine rich repeat	Biglycan (Precursor) GN=BGN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	biglycan precursor [Canis lupus familiaris] 
ENSG00000182504(CEP97)	--	3.976771749	440	4.02510856	423	4.260814265	511	4.861981496	554	3.941949596	451	3.997285456	475	0.890812229	0.300613028	normal	0.967412176	0.070798064	normal	0.965514758	-0.113339229	normal	0.782273299	0.085795605	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16717|0|hsa:79598|CEP97, 2810403B08Rik, LRRIQ2; centrosomal protein 97kDa; K16717 centrosomal protein CEP97 (A)"	--	--	--	Leucine Rich repeats (2 copies);; Leucine-rich repeat;; Leucine rich repeat;; IQ calmodulin-binding motif	Centrosomal protein of 97 kDa GN=CEP97 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: centrosomal protein of 97 kDa [Ceratotherium simum simum]
ENSG00000182511(FES)	--	2.02338411	130	2.348939476	155	2.278413	144	1.34886873	86	1.219436528	78	1.231576992	78	0.596324043	-0.61788832	normal	0.009096697	-0.998145466	normal	0.058415672	-0.880060752	normal	0.011399572	-0.847500834	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07527|0|pps:100978064|FES; FES proto-oncogene, tyrosine kinase; K07527 tyrosine-protein kinase Fes/Fps [EC:2.7.10.2] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	"Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; Fes/CIP4, and EFC/F-BAR homology domain"	Tyrosine-protein kinase Fes/Fps GN=FES OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase Fes/Fps isoform 1 [Sus scrofa]
ENSG00000182512(GLRX5)	--	37.716384	840	39.257825	902	39.727045	914	49.41549	1116	44.869379	997	44.503884	996	0.776150596	0.378441286	normal	0.972044585	0.122843559	normal	0.97347949	0.115477055	normal	0.291396354	0.205700931	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Biological Process: cell redox homeostasis (GO:0045454);; 	K07390|1.43152e-66|pon:100431569|GLRX5; glutaredoxin 5; K07390 monothiol glutaredoxin (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Glutaredoxin	"Glutaredoxin-related protein 5, mitochondrial (Precursor) GN=GLRX5 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: glutaredoxin-related protein 5, mitochondrial [Condylura cristata]"
ENSG00000182518(FAM104B)	--	11.23769396	176	9.997954123	156	10.744645	175	11.31582757	188	9.294285	144	8.579006	136	0.965726201	0.063786168	normal	0.960253621	-0.135535753	normal	0.884124097	-0.368418408	normal	0.764305421	-0.137617975	normal	--	--	--	--	--	--	--	Family 104	Protein FAM104B GN=FAM104B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein CB1_002327003 [Camelus ferus]
ENSG00000182521(TBPL2)	--	0	0	0	0	0	0	0.029361851	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	"K03120|0|hsa:387332|TBPL2, TBP2, TRF3; TATA box binding protein like 2; K03120 transcription initiation factor TFIID TATA-box-binding protein (A)"	Basal transcription factors (ko03022);; Huntington's disease (ko05016);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	"Transcription factor TFIID (or TATA-binding protein, TBP)"	TATA box-binding protein-like protein 2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: TATA box-binding protein-like protein 2 [Galeopterus variegatus]
ENSG00000182534(MXRA7)	--	57.01476683	2068	52.00349372	1902	54.73128404	1996	71.28251305	2623	63.58234937	2357	60.29021331	2178	0.922696434	0.311943177	normal	0.939059089	0.287802057	normal	0.983304383	0.117515533	normal	0.161854293	0.241056357	normal	--	--	--	--	--	--	--	--	Matrix-remodeling-associated protein 7 GN=MXRA7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	Matrix-remodeling-associated protein 7 [Tupaia chinensis]
ENSG00000182541(LIMK2)	--	2.080773766	146	1.43410195	109	2.052089568	155	2.749462671	209	3.166656985	213	2.028509418	150	0.709435456	0.482439297	normal	0.005641977	0.935649061	normal	0.966797619	-0.05505113	normal	0.155159646	0.458765342	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; Biological Process: regulation of phosphorylation (GO:0042325);; "	K05744|0|hsa:3985|LIMK2; LIM domain kinase 2 (EC:2.7.11.1); K05744 LIM domain kinase 2 [EC:2.7.11.1] (A)	Axon guidance (ko04360);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810)	--	--	Protein kinase domain;; Protein tyrosine kinase;; PKC-activated protein phosphatase-1 inhibitor;; PDZ domain (Also known as DHR or GLGF);; LIM domain;; Lipopolysaccharide kinase (Kdo/WaaP) family	LIM domain kinase 2 GN=LIMK2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LIM domain kinase 2 isoform X1 [Ursus maritimus]
ENSG00000182544(MFSD5)	--	34.42446526	799	38.96046611	922	34.491717	829	34.29661921	812	35.160843	809	40.31338671	933	0.977001608	-0.007533669	normal	0.95249762	-0.209686124	normal	0.965432559	0.161934936	normal	0.957636091	-0.018622876	normal	--	--	Molecular Function: molybdate ion transmembrane transporter activity (GO:0015098);; Biological Process: molybdate ion transport (GO:0015689);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[G]	Carbohydrate transport and metabolism	Protein of unknown function (DUF791);; Major Facilitator Superfamily	Molybdate-anion transporter GN=MFSD5 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	Major facilitator superfamily domain-containing protein 5 [Tupaia chinensis]
ENSG00000182545(RNASE10)	--	0.653071	12	0.954345	18	0.569311	10	0.368345	7	1.11158	20	1.60416	30	--	--	--	0.988211803	0.120934917	normal	0.517731381	1.445192065	normal	--	--	--	--	--	--	--	--	--	--	Pancreatic ribonuclease	Inactive ribonuclease-like protein 10 (Precursor) GN=RNASE10 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: inactive ribonuclease-like protein 10 [Ceratotherium simum simum]
ENSG00000182551(ADI1)	--	21.15203537	761	22.47384599	816	24.70094883	886	29.40101317	1070	23.97169775	856	32.73121208	1166	0.501924266	0.460023606	normal	0.976048705	0.047529082	normal	0.756319536	0.387319727	normal	0.153049444	0.307295682	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: acireductone dioxygenase [iron(II)-requiring] activity (GO:0010309);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K08967|2.50624e-130|hsa:55256|ADI1, APL1, ARD, Fe-ARD, MTCBP1, Ni-ARD, SIPL, mtnD; acireductone dioxygenase 1 (EC:1.13.11.54); K08967 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [EC:1.13.11.53 1.13.11.54] (A)"	Cysteine and methionine metabolism (ko00270)	[S]	Function unknown	ARD/ARD' family;; Cupin domain;; AraC-like ligand binding domain	"1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase {ECO:0000255|HAMAP-Rule:MF_03154} OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase [Ailuropoda melanoleuca] "
ENSG00000182552(RWDD4)	--	12.00954631	408	11.51707034	363	12.11862363	404	14.4352271	511	12.58455429	425	11.44000709	381	0.897782945	0.29293451	normal	0.943819328	0.20527573	normal	0.965663052	-0.092499129	normal	0.618863599	0.142589737	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	RWD domain	RWD domain-containing protein 4 GN=RWDD4 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: RWD domain-containing protein 4 [Ceratotherium simum simum]
ENSG00000182557(SPNS3)	--	0.0281732	1	0.0272965	1	0.026889	0	0.111589	4	0.109839	3	0.0278295	1	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; Sugar (and other) transporter;; Organic Anion Transporter Polypeptide (OATP) family	Protein spinster homolog 3 GN=SPNS3 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: protein spinster homolog 3 [Galeopterus variegatus]
ENSG00000182568(SATB1)	--	0.182468021	22	0.234312862	21	0.136136852	10	0.122925069	12	0.254825231	14	0.058867508	6	0.963356682	-0.826122815	normal	0.97971155	-0.55696381	normal	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	CUT domain;; Homeobox domain	DNA-binding protein SATB1 GN=SATB1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-binding protein SATB1-like isoform X1 [Chrysochloris asiatica]
ENSG00000182575(NXPH3)	--	0.042133773	2	0.062246662	2	0.030322656	0	0.084037413	4	0.143778334	6	0.0417576	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16658|1.0714e-161|pps:100970793|NXPH3; neurexophilin 3; K16658 neurexophilin-3 (A)	--	--	--	Neurexophilin	Neurexophilin-3 (Precursor) GN=NXPH3 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: neurexophilin-3 [Canis lupus familiaris]
ENSG00000182578(CSF1R)	--	0	0	0.011985664	1	0.011781852	0	0.08584997	7	0.071511484	5	0.034363892	3	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05090|0|hsa:1436|CSF1R, C-FMS, CD115, CSF-1R, CSFR, FIM2, FMS, HDLS, M-CSF-R; colony stimulating factor 1 receptor (EC:2.7.10.1); K05090 macrophage colony-stimulating factor 1 receptor [EC:2.7.10.1] (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; Endocytosis (ko04144);; PI3K-Akt signaling pathway (ko04151);; Osteoclast differentiation (ko04380);; Hematopoietic cell lineage (ko04640);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Macrophage colony-stimulating factor 1 receptor (Precursor) GN=CSF1R OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: macrophage colony-stimulating factor 1 receptor [Galeopterus variegatus]
ENSG00000182580(EPHB3)	--	0.108925	9	0.16631	14	0.127768	10	0.145439	12	0.093987	7	0.227367	19	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05112|0|hsa:2049|EPHB3, ETK2, HEK2, TYRO6; EPH receptor B3 (EC:2.7.10.1); K05112 Eph receptor B3 [EC:2.7.10.1] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; GCC2 and GCC3	Ephrin type-B receptor 3 (Precursor) GN=EPHB3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	ephrin type-B receptor 3 precursor [Bos taurus]
ENSG00000182583(VCX)	--	0	0	0.0952896	2	0	0	0	0	0.0489828	0	0.098485884	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Variable charge X/Y family	--	--	--	--
ENSG00000182584(ACTL10)	--	0.163957	5	0.217317	7	0.181541	5	0.0958929	3	0.0947256	2	0.160673	5	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	--	--	--	[Z]	Cytoskeleton	Actin	Actin-like protein 10 GN=ACTL10 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: actin-like protein 10 [Ursus maritimus]
ENSG00000182585(EPGN)	--	0.154121001	2	0	0	0.314693	2	0	0	0	0	1.237932	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Epigen (Precursor) GN=EPGN OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: epigen isoform X1 [Tupaia chinensis]
ENSG00000182600(C2orf82)	--	22.96168875	1925	22.20839452	2127	21.17845581	1956	14.18383147	1406	22.49205891	1409	19.08798052	1608	0.410206261	-0.483640332	normal	0.049518022	-0.615033644	normal	0.929624768	-0.290682117	normal	0.001738628	-0.462742353	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf82 (Precursor) GN=C2orf82 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C2orf82 homolog [Physeter catodon]
ENSG00000182606(TRAK1)	--	13.70252969	1417	14.82164022	1522	14.76512791	1490	13.82840496	1412	12.617417	1291	14.15714889	1447	0.983019522	-0.035892946	normal	0.943160649	-0.258626528	normal	0.983058894	-0.050486851	normal	0.59683371	-0.115016829	normal	--	--	--	"K15369|0|hsa:22906|TRAK1, MILT1, OIP106; trafficking protein, kinesin binding 1; K15369 trafficking kinesin-binding protein 1 (A)"	--	[S]	Function unknown	HAP1 N-terminal conserved region;; Kinesin associated protein	Trafficking kinesin-binding protein 1 GN=TRAK1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: trafficking kinesin-binding protein 1 isoform X2 [Bison bison bison]
ENSG00000182612(TSPAN10)	--	5.047683501	140	3.718187556	106	6.062884	160	6.114957	169	5.576189251	157	6.93158	196	0.94429505	0.238380414	normal	0.685721398	0.538919461	normal	0.925808524	0.282077598	normal	0.347745674	0.342328759	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17351|0|hsa:83882|TSPAN10, OCSP; tetraspanin 10; K17351 tetraspanin-10 (A)"	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-10 GN=TSPAN10 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tetraspanin-10 [Galeopterus variegatus]
ENSG00000182621(PLCB1)	--	1.23581132	90	1.20827022	90	0.919520143	54	1.355810271	88	1.221121452	109	1.152700531	80	0.971467309	-0.062180184	normal	0.951529392	0.251066492	normal	0.870735762	0.546108815	normal	0.691636075	0.221237151	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: lipid catabolic process (GO:0016042);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05858|0|ptr:469875|PLCB1; phospholipase C, beta 1 (phosphoinositide-specific); K05858 phosphatidylinositol phospholipase C, beta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Chemokine signaling pathway (ko04062);; Phosphatidylinositol signaling system (ko04070);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010);; Huntington's disease (ko05016);; Chagas disease (American trypanosomiasis) (ko05142);; African trypanosomiasis (ko05143);; Amoebiasis (ko05146);; Pathways in cancer (ko05200)	[I]	Lipid transport and metabolism	"PLC-beta C terminal;; Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 GN=PLCB1 OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform X1 [Mustela putorius furo]"
ENSG00000182628(SKA2)	--	43.658877	1142	55.3733856	1346	50.69762	1213	61.14543	1517	57.206891	1381	59.84368276	1375	0.788961587	0.378383224	normal	0.982551739	0.015591058	normal	0.969630699	0.172358677	normal	0.331194775	0.185742565	normal	--	--	Cellular Component: condensed chromosome outer kinetochore (GO:0000940);; Cellular Component: spindle microtubule (GO:0005876);; Biological Process: chromosome segregation (GO:0007059);; Molecular Function: microtubule binding (GO:0008017);; Biological Process: cell division (GO:0051301);; 	--	--	--	--	--	Spindle and kinetochore-associated protein 2 GN=SKA2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: spindle and kinetochore-associated protein 2 [Oryctolagus cuniculus]
ENSG00000182636(NDN)	--	1.38886	42	1.29017	40	0.792023	24	0.0975955	3	0.0319083	0	0.325067	10	2.41E-06	-3.287655987	down	1.35E-08	-4.789094378	down	0.883655164	-1.155518845	normal	1.25E-06	-3.045330983	down	--	--	--	--	--	[S]	Function unknown	MAGE family	Necdin GN=NDN OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: necdin-like [Equus caballus] 
ENSG00000182652(OR4Q3)	--	0	0	0.206699	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:441669|OR4Q3, C14orf13, HSA6, OR14-3, OR4Q4, c14_5008; olfactory receptor, family 4, subfamily Q, member 3; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 4Q3 GN=OR4Q3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 4Q3-like [Mustela putorius furo] 
ENSG00000182670(TTC3)	--	23.72342434	3475	25.5092073	3605	28.37428723	3406	26.24155779	3848	28.873472	4166	25.63920211	3755	0.988939765	0.116214717	normal	0.983431466	0.187163936	normal	0.987773325	0.132387029	normal	0.478337614	0.145240117	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	"K15712|0|hsa:7267|TTC3, DCRR1, RNF105, TPRDIII; tetratricopeptide repeat domain 3; K15712 E3 ubiquitin-protein ligase TTC3 [EC:6.3.2.19] (A)"	--	--	--	"TPR repeat;; Ring finger domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TTC3 GN=TTC3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TTC3 isoformX2 [Canis lupus familiaris]
ENSG00000182676(PPP1R27)	--	0.2256783	3	0	0	0.2039348	3	0.0755647	2	0.0371707	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17566|7.75704e-96|pps:100993804|PPP1R27; protein phosphatase 1, regulatory subunit 27; K17566 protein phosphatase 1 regulatory subunit 27 (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Protein phosphatase 1 regulatory subunit 27 GN=PPP1R27 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: protein phosphatase 1 regulatory subunit 27 [Mustela putorius furo] 
ENSG00000182685(BRICD5)	--	29.172147	1270	27.68977	1295	29.449809	1361	25.554989	1188	28.215093	1237	27.157813	1282	0.975606985	-0.126967061	normal	0.979115759	-0.087428678	normal	0.979603144	-0.094454089	normal	0.645007908	-0.103656055	normal	--	--	--	--	--	--	--	BRICHOS domain	BRICHOS domain-containing protein 5 GN=BRICD5 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: BRICHOS domain-containing protein 5 isoform X1 [Myotis davidii]
ENSG00000182687(GALR2)	--	0.904951	14	0.251071	4	0.30376	4	0.510772	8	0.557372	8	0.696406	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04231|0|hsa:8811|GALR2, GAL2-R, GALNR2, GALR-2; galanin receptor 2; K04231 galanin receptor 2 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srw	Galanin receptor type 2 GN=GALR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: galanin receptor type 2 [Galeopterus variegatus]
ENSG00000182700(IGIP)	--	4.780169	508	3.89865464	411	3.831019906	416	3.204639025	361	3.90951222	471	4.457555	527	0.341055468	-0.521779713	normal	0.953036204	0.174561756	normal	0.857812069	0.331853792	normal	0.997409609	0.005540854	normal	--	--	--	--	--	--	--	--	IgA-inducing protein homolog (Precursor) GN=IGIP OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: IgA-inducing protein homolog [Oryctolagus cuniculus]
ENSG00000182704(TSKU)	--	163.6661901	7866	188.7705174	9142	150.9380701	7361	102.642422	4823	126.631953	6063	174.451076	8376	0.002224064	-0.736345965	normal	0.087147582	-0.613778939	normal	0.991089112	0.178033919	normal	0.312281383	-0.359110566	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K08130|0|hsa:25987|TSKU, E2IG4, LRRC54, TSK; tsukushi, small leucine rich proteoglycan; K08130 tsukushi (leucine-rich repeat-containing protein 54) (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich Repeat;; Leucine Rich repeats (2 copies);; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeats (6 copies)	Tsukushin (Precursor) GN=TSKU OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: tsukushin [Leptonychotes weddellii]
ENSG00000182712(CMC4)	--	17.241283	320	20.585512	364	16.4921302	295	12.16553997	232	13.5278585	248	15.6799698	299	0.556877856	-0.491991681	normal	0.276173146	-0.572126339	normal	0.967780591	0.011082655	normal	0.169686359	-0.350401462	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF1903)	Cx9C motif-containing protein 4 GN=CMC4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cx9C motif-containing protein 4 [Galeopterus variegatus] 
ENSG00000182718(ANXA2)	--	1489.313916	38688	1536.366294	40211	1541.7629	40171	1996.705048	52733	1726.226075	44356	1503.450301	39045	0.959316129	0.415973463	normal	0.998420571	0.120108195	normal	0.998757834	-0.049306122	normal	0.513988198	0.171118572	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	K17092|0|ptr:747018|ANXA2; annexin A2; K17092 annexin A2 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A2 GN=ANXA2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	NMDA receptor-regulated protein 2 [Pteropus alecto]
ENSG00000182747(SLC35D3)	--	0	0	0	0	0	0	0.0265817	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15281|0|hsa:340146|SLC35D3, FRCL1; solute carrier family 35, member D3; K15281 solute carrier family 35 (A)"	--	[GOU]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Triose-phosphate Transporter family	Solute carrier family 35 member D3 GN=SLC35D3 OS=Homo sapiens (Human) PE=2 SV=1	GOU	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: solute carrier family 35 member D3 [Trichechus manatus latirostris]
ENSG00000182749(PAQR7)	--	5.375132	265	4.79071	239	5.354732	270	4.30546	213	4.372975	212	2.5593498	130	0.871784986	-0.343743014	normal	0.947859139	-0.193074818	normal	0.000152678	-1.054040563	down	0.061187582	-0.502146803	normal	[R]	General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Membrane progestin receptor alpha GN=PAQR7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: membrane progestin receptor alpha isoform X1 [Tupaia chinensis] 
ENSG00000182752(PAPPA)	--	41.70146	8353	44.50665	9034	45.47434	9251	58.278185	11599	63.62325	13073	92.04289	18615	0.806970345	0.442732446	normal	0.562865549	0.5116553	normal	2.76E-07	1.000375337	up	0.057803202	0.680774626	normal	--	--	--	"K07762|0|hsa:5069|PAPPA, ASBABP2, DIPLA1, IGFBP-4ase, PAPA, PAPP-A, PAPPA1; pregnancy-associated plasma protein A, pappalysin 1 (EC:3.4.24.79); K07762 pappalysin-1 [EC:3.4.24.79] (A)"	--	--	--	Concanavalin A-like lectin/glucanases superfamily;; Sushi domain (SCR repeat);; LNR domain;; Pregnancy-associated plasma protein-A	Pappalysin-1 (Precursor) GN=PAPPA OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: pappalysin-1 [Ceratotherium simum simum]
ENSG00000182759(MAFA)	--	0.366637	12	0.118374	4	0.0574223	1	0.030346	1	0.11716	3	0.149753	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K07595|2.54753e-94|hsa:389692|MAFA, RIPE3b1, hMafA; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A; K07595 transcription factor MAFA (A)"	Type II diabetes mellitus (ko04930);; Maturity onset diabetes of the young (ko04950)	[K]	Transcription	bZIP Maf transcription factor;; Maf N-terminal region	Transcription factor MafA GN=MAFA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor MafA [Erinaceus europaeus]
ENSG00000182768(NGRN)	--	28.666682	3699	28.084959	3647	29.542348	3712	34.402599	4412	34.023049	4137	30.865231	3920	0.978486852	0.223380187	normal	0.986230285	0.160385726	normal	0.990989516	0.070337614	normal	0.452643026	0.151727405	normal	--	--	--	--	--	--	--	Neugrin	Neugrin (Precursor) GN=NGRN OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: neugrin [Equus przewalskii]
ENSG00000182771(GRID1)	--	0.169232074	9	0.455567	17	0.1532644	6	0.5940757	25	0.71600232	44	1.7546638	51	0.809575852	1.304893801	normal	0.306130679	1.277577606	normal	3.19E-06	2.797993433	up	0.002806043	1.886434071	up	[ET]	Amino acid transport and metabolism;; Signal transduction mechanisms	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05206|0|hsa:2894|GRID1, GluD1; glutamate receptor, ionotropic, delta 1; K05206 glutamate receptor delta-1 subunit (A)"	Neuroactive ligand-receptor interaction (ko04080)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Receptor family ligand binding region;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site"	"Glutamate receptor ionotropic, delta-1 (Precursor) GN=GRID1 OS=Homo sapiens (Human) PE=2 SV=2"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, delta-1 [Condylura cristata]"
ENSG00000182774(RPS17)	--	1856.078188	12025	1816.602328	12225	1788.376417	12163	2223.789345	15286	2044.089318	13116	1894.737983	12562	0.976499043	0.315305976	normal	0.996340317	0.080057222	normal	0.996748642	0.038270937	normal	0.519151941	0.148081419	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02962|6.16685e-73|tgu:100190658|ribosomal protein S17-like; K02962 small subunit ribosomal protein S17e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal S17	40S ribosomal protein S17 GN=RPS17 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S17 [Equus przewalskii]
ENSG00000182782(HCAR2)	--	0.143933	5	0.0285073	1	0.309848	10	0.1146	4	0.0560638	1	0.0285844	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08402|0|hsa:338442|HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g; hydroxycarboxylic acid receptor 2; K08402 G protein-coupled receptor 109 (A)"	cAMP signaling pathway (ko04024)	--	--	7 transmembrane receptor (rhodopsin family)	Hydroxycarboxylic acid receptor 2 GN=HCAR2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: hydroxycarboxylic acid receptor 2 [Galeopterus variegatus]
ENSG00000182791(CCDC87)	--	0.646287	36	0.641688	36	0.857405	48	0.504337	28	0.296969	16	0.355097	20	0.975008678	-0.375194896	normal	0.688988688	-1.119065339	normal	0.303315274	-1.210499024	normal	0.114929925	-0.928871257	normal	--	--	--	--	--	--	--	Microtubule associated protein (MAP65/ASE1 family)	Coiled-coil domain-containing protein 87 GN=CCDC87 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 87 [Galeopterus variegatus]
ENSG00000182795(C1orf116)	--	0.11573871	11	0.159808622	18	0.252552061	25	4.190261241	406	3.245367497	294	3.918733505	371	0	4.993841423	up	0	3.900221927	up	0	3.804516785	up	1.75E-40	4.289201962	up	--	--	--	--	--	--	--	Specifically androgen-regulated gene protein	Specifically androgen-regulated gene protein GN=SARG OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: specifically androgen-regulated gene protein [Ceratotherium simum simum]
ENSG00000182809(CRIP2)	--	71.52606642	1552	64.65872247	1447	61.91669576	1459	31.7700831	700	31.4950331	670	20.27189264	424	6.74E-10	-1.177749343	down	1.02E-08	-1.130477463	down	0	-1.78747421	down	6.62E-22	-1.335756201	down	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	Cysteine-rich protein 2 GN=CRIP2 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: cysteine-rich protein 2 [Pteropus alecto]
ENSG00000182810(DDX28)	--	7.88954	291	9.12574	341	6.88088	259	8.65162	320	10.0807	372	8.64487	321	0.962784491	0.105688252	normal	0.962917421	0.103664077	normal	0.900186486	0.299754769	normal	0.598314011	0.163658477	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX28 GN=DDX28 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX28 [Sus scrofa]
ENSG00000182827(ACBD3)	--	18.9621	1227	17.5119	1150	17.7751	1149	22.407	1459	22.2587	1436	22.2204	1436	0.958299347	0.218760929	normal	0.913417596	0.298643264	normal	0.897391271	0.313016265	normal	0.107844788	0.27538409	normal	--	--	Molecular Function: fatty-acyl-CoA binding (GO:0000062);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Golgi-dynamics membrane-trafficking;; Acyl CoA binding protein	Golgi resident protein GCP60 GN=ACBD3 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: Golgi resident protein GCP60 [Sarcophilus harrisii]
ENSG00000182831(C16orf72)	--	17.4477	2159	17.02057137	2105	15.37429143	1842	18.35271733	2171	18.92805301	2252	18.013572	2166	0.987466063	-0.022819587	normal	0.985830916	0.075907308	normal	0.964916883	0.225297991	normal	0.698782357	0.088409935	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4588)	UPF0472 protein C16orf72 GN=C16orf72 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0472 protein C16orf72 homolog [Monodelphis domestica]
ENSG00000182836(PLCXD3)	--	0.141632	18	0.108554414	13	0.133894488	15	1.612195	200	1.250952661	152	0.919451093	112	0	3.337296704	up	0	3.382802843	up	1.18E-12	2.773380019	up	2.78E-10	3.31149213	up	--	--	--	--	--	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain"	PI-PLC X domain-containing protein 3 GN=PLCXD3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: PI-PLC X domain-containing protein 3 [Orcinus orca] 
ENSG00000182853(VMO1)	--	1.245055998	12	0.679245	11	0.388021437	4	0.139907324	2	0.839628619	9	1.65361367	20	--	--	--	--	--	--	0.496945782	1.957575472	normal	--	--	--	--	--	--	--	--	--	--	Vitelline membrane outer layer protein I (VOMI)	Vitelline membrane outer layer protein 1 homolog (Precursor) GN=VMO1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: vitelline membrane outer layer protein 1 homolog [Galeopterus variegatus]
ENSG00000182858(ALG12)	--	4.592637603	531	5.367180782	465	4.790080778	444	4.794790495	531	4.8030604	596	4.416037621	551	0.971933666	-0.030743309	normal	0.853256064	0.335688584	normal	0.889722548	0.302275304	normal	0.402534623	0.19947506	normal	--	--	"Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K03847|0|hsa:79087|ALG12, CDG1G, ECM39, PP14673, hALG12; ALG12, alpha-1,6-mannosyltransferase (EC:2.4.1.260); K03847 alpha-1,6-mannosyltransferase [EC:2.4.1.260] (A)"	N-Glycan biosynthesis (ko00510)	[MU]	"Cell wall/membrane/envelope biogenesis;; Intracellular trafficking, secretion, and vesicular transport"	Alg9-like mannosyltransferase family	"Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase GN=ALG12 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase isoform X2 [Galeopterus variegatus]"
ENSG00000182870(GALNT9)	--	1.822522177	78	0.8466777	38	1.003679944	62	2.238136425	84	2.5328347	120	1.095525777	50	0.972284587	0.074665568	normal	1.07E-05	1.599845723	up	0.963042073	-0.310190141	normal	0.542395782	0.491113094	normal	--	--	--	"K00710|0|hsa:50614|GALNT9, GALNAC-T9, GALNACT9; polypeptide N-acetylgalactosaminyltransferase 9 (EC:2.4.1.41); K00710 polypeptide N-acetylgalactosaminyltransferase [EC:2.4.1.41] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferase family 2;; Ricin-type beta-trefoil lectin domain;; Glycosyltransferase like family 2	Polypeptide N-acetylgalactosaminyltransferase 9 GN=GALNT9 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polypeptide N-acetylgalactosaminyltransferase 9 [Chrysochloris asiatica]
ENSG00000182871(COL18A1)	--	62.703618	7555	68.585856	8189	60.75064167	7364	68.6363958	8211	74.96539437	9024	57.94208426	7064	0.994630949	0.089276499	normal	0.994127716	0.118632347	normal	0.994584622	-0.068281407	normal	0.855593371	0.050837136	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Molecular Function: protein binding (GO:0005515);; Biological Process: cell adhesion (GO:0007155);; Cellular Component: extracellular matrix (GO:0031012);; 	"K06823|0|ptr:474050|COL18A1; collagen, type XVIII, alpha 1; K06823 collagen, type XVIII, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	Collagenase NC10 and Endostatin;; Domain of Unknown Function (DUF959);; Collagen triple helix repeat (20 copies);; Fz domain;; Concanavalin A-like lectin/glucanases superfamily	Endostatin (Precursor) GN=COL18A1 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: collagen alpha-1(XVIII) chain isoform 2 [Ceratotherium simum simum]
ENSG00000182872(RBM10)	--	17.48392	1330	16.18529	1255	18.122589	1431	18.29306	1409	19.9214886	1531	18.21552	1422	0.982178209	0.05235434	normal	0.939397589	0.265070769	normal	0.983459971	-0.017375229	normal	0.667064915	0.098309712	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K13094|0|mcf:102135427|RBM10; RNA binding motif protein 10; K13094 RNA-binding protein 5/10 (A)	--	[R]	General function prediction only	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; G-patch domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; DExH-box splicing factor binding site;; Zn-finger in Ran binding protein and others"	RNA-binding protein 10 GN=RBM10 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: RNA-binding protein 10 isoform X1 [Felis catus]
ENSG00000182885(ADGRG3)	--	0.068692558	2	0.06129527	3	0.099456357	2	0.041617614	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08452|0|hsa:222487|GPR97, PB99, PGR26, ADGRG3; G protein-coupled receptor 97; K08452 G protein-coupled receptor 97 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Latrophilin/CL-1-like GPS domain	Probable G-protein coupled receptor 97 (Precursor) GN=GPR97 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 97 [Galeopterus variegatus]
ENSG00000182890(GLUD2)	--	4.25843	225	4.53774	236	3.79843	207	2.290375	127	2.69849	148	1.791986	100	0.01538251	-0.848108966	normal	0.140228784	-0.688988074	normal	0.00082848	-1.046677641	down	0.001536519	-0.854864028	normal	[E]	Amino acid transport and metabolism	Biological Process: cellular amino acid metabolic process (GO:0006520);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00261|0|hsa:2747|GLUD2, GDH2, GLUDP1; glutamate dehydrogenase 2 (EC:1.4.1.3); K00261 glutamate dehydrogenase (NAD(P)+) [EC:1.4.1.3] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Arginine and proline metabolism (ko00330);; D-Glutamine and D-glutamate metabolism (ko00471);; Nitrogen metabolism (ko00910);; Proximal tubule bicarbonate reclamation (ko04964)"	[E]	Amino acid transport and metabolism	"Glutamate/Leucine/Phenylalanine/Valine dehydrogenase;; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain"	"Glutamate dehydrogenase 2, mitochondrial (Precursor) GN=GLUD2 OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: glutamate dehydrogenase 1, mitochondrial [Orycteropus afer afer]"
ENSG00000182899(RPL35A)	--	322.5010318	2576	319.4067304	2543	336.958266	2606	391.723925	3272	333.3648112	2613	313.439328	2542	0.930172766	0.314041371	normal	0.988688346	0.017738698	normal	0.988618413	-0.04413856	normal	0.635125073	0.103488224	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02917|1.57893e-75|umr:103678951|60S ribosomal protein L35a; K02917 large subunit ribosomal protein L35Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L35Ae	60S ribosomal protein L35a GN=RPL35A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	60S ribosomal protein L35a [Bos taurus] 
ENSG00000182901(RGS7)	--	0.043599626	2	0.032614087	1	0.064545542	1	0.043457489	2	0.12417814	4	0.108070688	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: signal transducer activity (GO:0004871);; Cellular Component: heterotrimeric G-protein complex (GO:0005834);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Biological Process: intracellular signal transduction (GO:0035556);; 	K16449|0|pale:102882108|RGS7; regulator of G-protein signaling 7; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	"Regulator of G protein signaling domain;; Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP);; GGL domain"	Regulator of G-protein signaling 7 GN=RGS7 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 7 isoform X1 [Pteropus alecto]
ENSG00000182902(SLC25A18)	--	0.28109075	11	0.377419504	15	0.248283209	9	0.227880904	9	0.2477198	9	0.402790603	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15107|0|hsa:83733|SLC25A18, GC2; solute carrier family 25 (glutamate carrier), member 18; K15107 solute carrier family 25 (mitochondrial glutamate transporter), member 18/22 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial glutamate carrier 2 GN=SLC25A18 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial glutamate carrier 2 [Orycteropus afer afer]
ENSG00000182903(ZNF721)	--	6.965940442	396	5.288246981	407	7.38362485	433	5.147322448	330	5.234050084	393	5.643964216	321	0.90018488	-0.292620873	normal	0.966562163	-0.07165507	normal	0.656511399	-0.438300421	normal	0.2878226	-0.264592857	normal	[R]	General function prediction only	--	K09228|0|hsa:170960|ZNF721; zinc finger protein 721; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; GAGA factor;; Zinc ribbon domain;; XPA protein N-terminal;; TFIIH C1-like domain;; MNLL subunit"	Zinc finger protein 721 GN=ZNF721 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	"PREDICTED: zinc finger protein 208-like, partial [Monodelphis domestica]"
ENSG00000182923(CEP63)	--	9.646169452	381	8.190377049	358	7.766477608	353	8.717093819	361	8.2879271	368	8.227552861	337	0.963553451	-0.108176175	normal	0.967965258	0.018243611	normal	0.966174874	-0.074882666	normal	0.884101377	-0.056197622	normal	--	--	--	K16763|0|ptr:460713|CEP63; centrosomal protein 63kDa; K16763 centrosomal protein CEP63 (A)	--	--	--	--	Centrosomal protein of 63 kDa GN=CEP63 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: centrosomal protein of 63 kDa isoform 2 [Ceratotherium simum simum]
ENSG00000182934(SRPRA)	--	30.341253	1786	29.85236	1774	29.948828	1775	29.621257	1745	29.2908	1715	32.578098	1924	0.984503573	-0.06428136	normal	0.983783443	-0.070163154	normal	0.982641883	0.107910005	normal	0.983948554	-0.007726453	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: signal recognition particle binding (GO:0005047);; Molecular Function: GTP binding (GO:0005525);; Cellular Component: signal recognition particle receptor complex (GO:0005785);; Biological Process: SRP-dependent cotranslational protein targeting to membrane (GO:0006614);; Biological Process: intracellular protein transport (GO:0006886);; 	K13431|0|pps:100976470|SRPR; signal recognition particle receptor (docking protein); K13431 signal recognition particle receptor subunit alpha (A)	Protein export (ko03060)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Signal recognition particle, alpha subunit, N-terminal;; SRP54-type protein, GTPase domain;; ArgK protein;; CobQ/CobB/MinD/ParA nucleotide binding domain;; SRP54-type protein, helical bundle domain"	Signal recognition particle receptor subunit alpha GN=SRPR OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: signal recognition particle receptor subunit alpha [Oryctolagus cuniculus]
ENSG00000182944(EWSR1)	--	76.85404299	3788	76.98175583	3854	72.70245338	3754	92.65445298	4782	97.94371782	4778	82.666887	4180	0.950789379	0.305235144	normal	0.960563521	0.288521878	normal	0.987713003	0.146726811	normal	0.156978892	0.248265303	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13209|1.66292e-93|phd:102343830|EWSR1; EWS RNA-binding protein 1; K13209 RNA-binding protein EWS (A)	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"Zn-finger in Ran binding protein and others;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein EWS GN=EWSR1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RNA-binding protein EWS [Echinops telfairi]
ENSG00000182950(ODF3L1)	--	0.102514	2	0.360182	7	0.199682	3	0.256102	5	0.248456	4	0.151304	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sperm-tail PG-rich repeat	Outer dense fiber protein 3-like protein 1 GN=ODF3L1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: outer dense fiber protein 3-like protein 1 [Equus caballus] 
ENSG00000182952(HMGN4)	--	37.5979528	1070	29.4793263	820	33.40333561	914	44.92484	1264	36.132847	970	32.401381	913	0.958447876	0.209276685	normal	0.949301734	0.220559928	normal	0.978535708	-0.009854433	normal	0.667730417	0.144224025	normal	--	--	--	K11302|8.11634e-14|pps:100983436|HMGN4; high mobility group nucleosomal binding domain 4; K11302 high-mobility group nucleosome-binding domain-containing protein 4 (A)	--	--	--	HMG14 and HMG17	High mobility group nucleosome-binding domain-containing protein 4 GN=HMGN4 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: high mobility group nucleosome-binding domain-containing protein 4 isoform X1 [Equus caballus] 
ENSG00000182957(SPATA13)	--	1.5492941	251	1.831457442	294	1.723452	301	2.265017279	344	1.7480104	297	1.625831818	270	0.733208392	0.421676301	normal	0.966760327	-0.006745262	normal	0.954302157	-0.164223879	normal	0.821676026	0.084996504	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Variant SH3 domain;; SH3 domain;; PH domain;; Variant SH3 domain	Spermatogenesis-associated protein 13 GN=SPATA13 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: spermatogenesis-associated protein 13 [Tupaia chinensis]
ENSG00000182963(GJC1)	--	12.10761799	1319	14.00103063	1348	12.3214747	1418	10.37926866	1091	8.980032621	1014	9.327026966	946	0.903611095	-0.304235352	normal	0.634974306	-0.431629015	normal	0.072550127	-0.591459188	normal	0.004081985	-0.442569791	normal	--	--	--	"K07616|0|ptr:454736|GJC1, GJA7, GJD3; gap junction protein, gamma 1, 45kDa; K07616 gap junction protein, alpha 7 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction gamma-1 protein GN=GJC1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: gap junction gamma-1 protein isoform X1 [Physeter catodon] 
ENSG00000182973(CNOT10)	--	13.30310914	686	14.15834097	738	13.60323312	694	12.50553202	649	13.93442858	709	13.42475454	681	0.969194084	-0.110567707	normal	0.972541302	-0.079096367	normal	0.974757903	-0.035494225	normal	0.786760681	-0.075910399	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K12607|0|mcf:101865884|CNOT10; CCR4-NOT transcription complex subunit 10; K12607 CCR4-NOT transcription complex subunit 10 (A)	RNA degradation (ko03018)	[R]	General function prediction only	Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	CCR4-NOT transcription complex subunit 10 GN=CNOT10 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 10 isoform 1 [Ceratotherium simum simum]
ENSG00000182974(RP11-294C11.1)	--	0	0	0	0	0.090847	0	0.180465	2	0.178155	1	0.0901097	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:390538|OR4M2, OR15-3; olfactory receptor, family 4, subfamily M, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 4M2 GN=OR4M2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 4M1 isoform X1 [Oryctolagus cuniculus]
ENSG00000182979(MTA1)	--	37.36337305	2465	31.69094082	2181	34.71851026	2399	34.05930045	2258	31.67881265	2168	29.96633276	2131	0.980973941	-0.157271954	normal	0.987078872	-0.030030686	normal	0.97740318	-0.179074157	normal	0.551414142	-0.124848667	normal	--	--	"Molecular Function: chromatin binding (GO:0003682);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K11660|0|ggo:101134898|MTA1; metastasis-associated protein MTA1; K11660 metastasis-associated protein MTA (A)	--	[B]	Chromatin structure and dynamics	BAH domain;; ELM2 domain;; GATA zinc finger	Metastasis-associated protein MTA1 GN=MTA1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: metastasis-associated protein MTA1 isoform 1 [Ceratotherium simum simum]
ENSG00000182985(CADM1)	--	18.01760351	1053	16.52703357	1073	15.01587765	945	23.72757004	1497	31.31917327	1969	24.84585221	1570	0.434280766	0.476151204	normal	8.82E-05	0.853485505	normal	0.003132312	0.723179583	normal	0.000324618	0.692436795	normal	--	--	--	K06781|0|mcf:102135338|CADM1; cell adhesion molecule 1; K06781 cell adhesion molecule 1 (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Cell adhesion molecule 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: cell adhesion molecule 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000182993(C12orf60)	--	1.651263086	42	1.280215612	32	1.998220845	49	1.515112	40	1.935664949	49	0.935431532	24	0.980851845	-0.097563801	normal	0.930346841	0.571321843	normal	0.609648511	-0.99336368	normal	0.877071809	-0.144018714	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF4533)	Uncharacterized protein C12orf60 GN=C12orf60 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C12orf60 homolog isoform X1 [Tupaia chinensis] 
ENSG00000183010(PYCR1)	--	59.50004981	1757	58.37082112	1724	53.12119175	1609	37.32323314	1130	51.78193045	1388	39.71112836	1112	0.012188318	-0.666890029	normal	0.883335941	-0.333851663	normal	0.183375225	-0.540684108	normal	0.00052242	-0.508950925	normal	--	--	--	K00286|0|ptr:454977|PYCR1; pyrroline-5-carboxylate reductase 1; K00286 pyrroline-5-carboxylate reductase [EC:1.5.1.2] (A)	Arginine and proline metabolism (ko00330);; Biosynthesis of amino acids (ko01230)	[E]	Amino acid transport and metabolism	Pyrroline-5-carboxylate reductase dimerisation;; NADP oxidoreductase coenzyme F420-dependent;; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus	"Pyrroline-5-carboxylate reductase 1, mitochondrial GN=PYCR1 OS=Homo sapiens (Human) PE=1 SV=2"	E	Amino acid transport and metabolism	"PREDICTED: pyrroline-5-carboxylate reductase 1, mitochondrial isoform X1 [Balaenoptera acutorostrata scammoni]"
ENSG00000183011(NAA38)	--	83.002545	702	80.52062	721	81.33275	741	89.86683	749	86.574616	702	73.04393	648	0.974142407	0.062529925	normal	0.973519257	-0.059827606	normal	0.951792269	-0.201331427	normal	0.821676026	-0.065553895	normal	--	--	--	--	--	[K]	Transcription	LSM domain	"N-alpha-acetyltransferase 38, NatC auxiliary subunit GN=NAA38 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: LSM domain-containing protein 1 [Bubalus bubalis]
ENSG00000183018(SPNS2)	--	0.44477651	28	0.527986001	33	0.531753	33	1.018704722	64	0.604089071	37	1.881500019	120	0.191570338	1.120131526	normal	0.980889593	0.137672277	normal	4.01E-07	1.807861995	up	0.233940355	1.214188288	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[G]	Carbohydrate transport and metabolism	Major Facilitator Superfamily;; Sugar (and other) transporter;; Organic Anion Transporter Polypeptide (OATP) family;; MFS/sugar transport protein	Protein spinster homolog 2 GN=SPNS2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	"PREDICTED: protein spinster homolog 2, partial [Orycteropus afer afer]"
ENSG00000183020(AP2A2)	--	28.912362	1860	29.15311382	1807	34.32944179	1833	26.2982315	2028	31.88754999	2168	22.72142214	1771	0.984089173	0.093848514	normal	0.959646098	0.241157225	normal	0.984965093	-0.057885427	normal	0.667730417	0.096067511	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K11824|0|hsa:161|AP2A2, ADTAB, CLAPA2, HIP-9, HIP9, HYPJ; adaptor-related protein complex 2, alpha 2 subunit; K11824 AP-2 complex subunit alpha (A)"	Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Adaptin N terminal region;; Alpha adaptin AP2, C-terminal domain;; Adaptin C-terminal domain;; non-SMC mitotic condensation complex subunit 1"	AP-2 complex subunit alpha-2 GN=AP2A2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-2 complex subunit alpha-2 [Trichechus manatus latirostris]
ENSG00000183023(SLC8A1)	--	1.898929572	199	0.98751202	110	1.568522723	127	0.432568024	78	1.077797135	111	0.422109393	53	2.40E-06	-1.364592467	down	0.968625923	-0.008257397	normal	0.00088949	-1.245380573	down	0.13134065	-0.871382128	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cell communication (GO:0007154);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	K05849|0|ggo:101140086|SLC8A1; sodium/calcium exchanger 1 isoform 1; K05849 solute carrier family 8 (sodium/calcium exchanger) (A)	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Protein digestion and absorption (ko04974)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Calx-beta domain;; Sodium/calcium exchanger protein	Sodium/calcium exchanger 1 (Precursor) GN=SLC8A1 OS=Homo sapiens (Human) PE=1 SV=3	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: sodium/calcium exchanger 1-like isoform X1 [Tupaia chinensis] 
ENSG00000183032(SLC25A21)	--	0.835602014	34	0.754042	24	1.14538	31	0.969359	40	0.568635	23	0.849612	35	0.980157612	0.195482709	normal	0.986337265	-0.077817716	normal	0.982249837	0.159470092	normal	0.911558094	0.117294488	normal	--	--	--	"K15110|0|hsa:89874|SLC25A21, ODC, ODC1; solute carrier family 25 (mitochondrial oxoadipate carrier), member 21; K15110 solute carrier family 25 (mitochondrial 2-oxodicarboxylate transporter), member 21 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial 2-oxodicarboxylate carrier GN=SLC25A21 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: mitochondrial 2-oxodicarboxylate carrier [Oryctolagus cuniculus]
ENSG00000183044(ABAT)	--	0.169156998	16	0.239652054	9	0.041264145	3	0.406760282	38	0.689026304	65	0.2377692	16	0.650887802	1.143943225	normal	2.86E-07	2.64190295	up	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: transaminase activity (GO:0008483);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	"K13524|0|hsa:18|ABAT, GABA-AT, GABAT, NPD009; 4-aminobutyrate aminotransferase (EC:2.6.1.19 2.6.1.22); K13524 4-aminobutyrate aminotransferase / (S)-3-amino-2-methylpropionate transaminase [EC:2.6.1.19 2.6.1.22] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Valine, leucine and isoleucine degradation (ko00280);; beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Butanoate metabolism (ko00650);; GABAergic synapse (ko04727)"	[E]	Amino acid transport and metabolism	Aminotransferase class-III	"4-aminobutyrate aminotransferase, mitochondrial (Precursor) GN=ABAT OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: 4-aminobutyrate aminotransferase, mitochondrial [Pteropus alecto]"
ENSG00000183048(SLC25A10)	--	178.9264968	3721	165.5900994	3460	190.3213783	4001	201.4925323	4132	197.8239682	3996	167.968351	3365	0.989304737	0.120270462	normal	0.983034437	0.186282174	normal	0.967802993	-0.257939114	normal	0.955665903	0.018024713	normal	--	--	--	"K13577|8.57055e-131|phd:102334607|SLC25A10; solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10; K13577 solute carrier family 25 (mitochondrial dicarboxylate transporter), member 10 (A)"	Proximal tubule bicarbonate reclamation (ko04964)	[C]	Energy production and conversion	Mitochondrial carrier protein;; Mitochondrial carrier protein	Mitochondrial dicarboxylate carrier GN=SLC25A10 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: mitochondrial dicarboxylate carrier isoform X1 [Pantholops hodgsonii]
ENSG00000183049(CAMK1D)	--	10.51069858	1010	9.201978781	1082	10.402155	1060	7.751134659	806	8.661066847	1048	7.637603425	866	0.82201641	-0.355728528	normal	0.978145124	-0.067392625	normal	0.901787958	-0.299443282	normal	0.211688712	-0.233517446	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08794|0|tup:102478578|CAMK1D; calcium/calmodulin-dependent protein kinase ID; K08794 calcium/calmodulin-dependent protein kinase I [EC:2.7.11.17] (A)	Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Calcium/calmodulin-dependent protein kinase type 1D GN=CAMK1D OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: calcium/calmodulin-dependent protein kinase type 1D isoform X1 [Tupaia chinensis]
ENSG00000183054(RGPD6)	--	1.185454005	7	0.157598	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:84220|RGPD5, BS-63, BS63, HEL161, RGP5; RANBP2-like and GRIP domain containing 5; K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; GRIP domain;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RANBP2-like and GRIP domain-containing protein 5/6 GN=RGPD6 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ceratotherium simum simum]
ENSG00000183060(LYSMD4)-2	--	1.21964	45	1.38113	51	1.28642	47	1.16338	43	0.971238	36	1.18015	44	0.979991201	-0.093166028	normal	0.9405923	-0.505977945	normal	0.979050497	-0.10011856	normal	0.750777125	-0.23862188	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000183060(LYSMD4)-3	--	4.781702805	198	4.266672868	210	3.89100411	237	3.763482504	167	3.682835629	176	2.93023726	131	0.928143765	-0.274164655	normal	0.924903121	-0.274081274	normal	0.011524726	-0.856155288	normal	0.120712638	-0.465944952	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000183067(IGSF5)	--	0.053845	2	0	0	0	0	0	0	0	0	0.0267321	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06786|0|hsa:150084|IGSF5, GSF5, JAM4; immunoglobulin superfamily, member 5; K06786 junctional adhesion molecule 4 (A)"	Tight junction (ko04530);; Epithelial cell signaling in Helicobacter pylori infection (ko05120)	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain	Immunoglobulin superfamily member 5 GN=IGSF5 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: immunoglobulin superfamily member 5 [Galeopterus variegatus]
ENSG00000183072(NKX2-5)	--	7.589754379	190	9.765303001	169	9.719262364	182	12.71861735	297	10.4245202	248	11.64937823	282	0.232534919	0.609658781	normal	0.544763797	0.527968541	normal	0.22339178	0.619299431	normal	0.019884918	0.590882211	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09345|1.18665e-136|ggo:101124584|NKX2-5; homeobox protein Nkx-2.5 isoform 1; K09345 homeobox protein Nkx-2.5 (A)	--	[K]	Transcription	Homeobox domain	Homeobox protein Nkx-2.5 GN=NKX2-5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	homeobox protein Nkx-2.5 [Bos taurus] 
ENSG00000183077(AFMID)	--	19.84470682	326	16.81132043	265	21.38906417	331	14.8292386	271	18.65299963	284	14.4242331	225	0.901785804	-0.295879287	normal	0.963790785	0.078041762	normal	0.326080738	-0.562063247	normal	0.354561832	-0.262700556	normal	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01432|0|hsa:125061|AFMID, FKF, KF, KFA; arylformamidase (EC:3.5.1.9); K01432 arylformamidase [EC:3.5.1.9] (A)"	Tryptophan metabolism (ko00380);; Glyoxylate and dicarboxylate metabolism (ko00630)	[E]	Amino acid transport and metabolism	alpha/beta hydrolase fold;; Alpha/beta hydrolase family;; Carboxylesterase family	Kynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_03014} OS=Homo sapiens (Human) PE=2 SV=2	E	Amino acid transport and metabolism	PREDICTED: kynurenine formamidase [Galeopterus variegatus]
ENSG00000183087(GAS6)	--	7.00984	337	5.97002	294	5.34163	266	5.88578	285	5.94291	285	4.85357	235	0.916616923	-0.271272116	normal	0.964786484	-0.065936293	normal	0.950115669	-0.185931519	normal	0.578178603	-0.178092913	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; 	"K05464|0|hsa:2621|GAS6, AXLLG, AXSF; growth arrest-specific 6; K05464 growth arrest-specific 6 (A)"	--	--	--	Laminin G domain;; Laminin G domain;; Calcium-binding EGF domain;; Coagulation Factor Xa inhibitory site;; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain;; Complement Clr-like EGF-like;; EGF-like domain	Growth arrest-specific protein 6 (Precursor) GN=GAS6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: growth arrest-specific protein 6 [Pteropus alecto]
ENSG00000183091(NEB)	--	0.034266646	2	0.020977056	9	0.053527307	2	0.020736107	8	0.03142746	7	0.07055102	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K18267|0|hsa:4703|NEB, NEB177D, NEM2; nebulin; K18267 nebulin (A)"	--	[Z]	Cytoskeleton	Nebulin repeat;; Metallopeptidase family M24;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain	Nebulin GN=NEB OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: nebulin [Equus caballus]
ENSG00000183092(BEGAIN)	--	1.232578829	57	1.964519925	75	1.109487535	62	3.235833034	135	4.073565698	175	1.913735682	79	0.001405776	1.191624455	up	0.00027099	1.184882215	up	0.950597023	0.334058384	normal	0.085741484	0.981300829	normal	--	--	--	--	--	--	--	--	Brain-enriched guanylate kinase-associated protein GN=BEGAIN OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: brain-enriched guanylate kinase-associated protein isoform X3 [Bos taurus]
ENSG00000183098(GPC6)	--	5.240800095	527	4.1057656	410	4.05709	405	7.56988342	772	9.30038	948	7.41338	765	0.292173241	0.51870945	normal	7.01E-09	1.184881031	up	6.32E-05	0.906742116	normal	3.60E-06	0.867559509	normal	--	--	Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Cellular Component: membrane (GO:0016020);; Molecular Function: heparan sulfate proteoglycan binding (GO:0043395);; 	K08112|0|pps:100975429|GPC6; glypican 6; K08112 glypican 6 (A)	--	[T]	Signal transduction mechanisms	Glypican	Secreted glypican-6 (Precursor) GN=GPC6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: glypican-6 [Myotis davidii]
ENSG00000183111(ARHGEF37)	--	1.20066	125	1.287203	137	0.776602032	82	1.473053	155	1.7248491	178	0.991044	103	0.936510697	0.276451777	normal	0.892455514	0.352849291	normal	0.942314808	0.315455798	normal	0.54372207	0.319022748	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; BAR domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; Bacterial SH3 domain	Rho guanine nucleotide exchange factor 37 GN=ARHGEF37 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 37 isoform X2 [Equus przewalskii]
ENSG00000183114(FAM43B)	--	3.40746	140	3.31919	140	3.1572	136	2.75744	115	2.28282	94	2.00948	84	0.928535748	-0.31085398	normal	0.623879507	-0.588311515	normal	0.391566272	-0.693529419	normal	0.150883387	-0.527917271	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Phosphotyrosine interaction domain (PTB/PID)	Protein FAM43B GN=FAM43B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM43B [Ceratotherium simum simum]
ENSG00000183128(CALHM3)	--	0	0	0	0	0	0	0.0402986	1	0.0391989	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Calcium homeostasis modulator	Calcium homeostasis modulator protein 3 GN=CALHM3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: calcium homeostasis modulator protein 3 [Ceratotherium simum simum]
ENSG00000183134(PTGDR2)	--	0.241314	11	0.191837	9	0.104667	4	0.0217199	1	0.0637025	2	0.0648625	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06715|0|hsa:11251|PTGDR2, CD294, CRTH2, DL1R, DP2, GPR44; prostaglandin D2 receptor 2; K06715 G protein-coupled receptor 44 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Prostaglandin D2 receptor 2 GN=PTGDR2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: prostaglandin D2 receptor 2 isoform X1 [Equus caballus] 
ENSG00000183137(CEP57L1)	--	4.08371564	175	4.35231701	183	3.1965985	154	4.190595231	182	4.34176533	183	4.47293128	163	0.966997517	0.025531464	normal	0.965764338	-0.021250946	normal	0.965838259	0.072953749	normal	0.973262061	0.022637391	normal	--	--	Molecular Function: microtubule binding (GO:0008017);; Molecular Function: identical protein binding (GO:0042802);; Molecular Function: gamma-tubulin binding (GO:0043015);; 	K16762|0|mcf:102134326|CEP57L1; centrosomal protein 57kDa-like 1; K16762 centrosomal protein CEP57 (A)	--	--	--	Centrosome localisation domain of Cep57;; Centrosome microtubule-binding domain of Cep57	Centrosomal protein CEP57L1 GN=CEP57L1 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: centrosomal protein CEP57L1 isoform X1 [Galeopterus variegatus]
ENSG00000183145(RIPPLY3)	--	0.462649611	17	0.748707948	28	0.368575158	13	0.312886383	12	0.651993116	25	0.542093569	21	--	--	--	0.983928366	-0.174921111	normal	0.978443725	0.62585678	normal	1	-0.020542736	normal	--	--	--	--	--	--	--	Transcription Regulator	Protein ripply3 GN=RIPPLY3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: protein ripply3 [Ursus maritimus]
ENSG00000183148(ANKRD20A2)	--	0.0548881	4	0.013672	1	0.0137033	0	0.0543717	4	0.0398217	2	0.1103095	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17299|0|hsa:441430|ANKRD20A2; ankyrin repeat domain 20 family, member A2; K17299 POTE ankyrin domain family protein (A)"	--	[R]	General function prediction only	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 20A2 GN=ANKRD20A2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like isoform X4 [Bos taurus]
ENSG00000183150(GPR19)	--	1.87346151	43	0.877429915	31	1.698271487	45	0.8013571	17	0.406769342	10	0.1089059	4	0.297475516	-1.293643352	normal	0.371646147	-1.517331865	normal	3.02E-06	-3.083908322	down	0.000444476	-1.965254861	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04316|0|hsa:2842|GPR19; G protein-coupled receptor 19; K04316 G protein-coupled receptor 19 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Probable G-protein coupled receptor 19 GN=GPR19 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 19 [Galeopterus variegatus] 
ENSG00000183153(GJD3)	--	33.4365	280	31.2843	271	34.1406	301	21.2417	180	22.838	193	27.1702	229	0.127847616	-0.663680046	normal	0.567095802	-0.507743798	normal	0.789979839	-0.400393605	normal	0.038777693	-0.521389748	normal	--	--	--	"K07627|2.15073e-132|hsa:125111|GJD3, CX31.9, Cx30.2, GJA11, GJC1; gap junction protein, delta 3, 31.9kDa; K07627 gap junction protein, chi 1 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction delta-3 protein GN=GJD3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: gap junction delta-3 protein [Oryctolagus cuniculus]
ENSG00000183155(RABIF)	--	9.763578	400	7.664678	323	8.095381	323	8.413505	349	8.021495	344	8.021003	333	0.936735379	-0.226672179	normal	0.965357639	0.069134169	normal	0.967826116	0.035532719	normal	0.900709545	-0.04932653	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Mss4 protein	Guanine nucleotide exchange factor MSS4 GN=RABIF OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: guanine nucleotide exchange factor MSS4 [Trichechus manatus latirostris]
ENSG00000183160(TMEM119)	--	0.019891366	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: ossification (GO:0001503);; 	--	--	--	--	--	Transmembrane protein 119 (Precursor) GN=TMEM119 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 119 [Loxodonta africana]
ENSG00000183161(FANCF)	--	6.8147	405	7.16492	427	6.23197	368	6.4757	388	6.51775	389	7.09936	425	0.965639991	-0.09233957	normal	0.956474597	-0.155315892	normal	0.946734313	0.198705189	normal	0.96805012	-0.018747954	normal	--	--	--	"K10893|0|hsa:2188|FANCF, FAF; Fanconi anemia, complementation group F; K10893 fanconi anemia group F protein (A)"	Fanconi anemia pathway (ko03460)	--	--	Fanconi anemia group F protein (FANCF)	Fanconi anemia group F protein GN=FANCF OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: Fanconi anemia, complementation group F [Sus scrofa]"
ENSG00000183172(SMDT1)	--	7.098091	157	8.0243259	182	5.313293	124	9.819228	221	9.3426579	201	10.104218	225	0.74171167	0.458650582	normal	0.960120283	0.120874508	normal	0.017730747	0.843546887	normal	0.12714462	0.461013355	normal	--	--	Biological Process: calcium ion transmembrane import into mitochondrion (GO:0036444);; Biological Process: mitochondrial calcium ion homeostasis (GO:0051560);; Cellular Component: uniplex complex (GO:1990246);; 	--	--	[S]	Function unknown	Putative mitochondrial precursor protein	"Essential MCU regulator, mitochondrial (Precursor) GN=SMDT1 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: single-pass membrane protein with aspartate-rich tail 1, mitochondrial [Myotis brandtii] "
ENSG00000183186(C2CD4C)	--	1.04958	58	0.536794	31	0.659529	38	0.590321	33	0.63052	35	0.195771	11	0.727563794	-0.815401601	normal	0.981524794	0.146912473	normal	0.084687832	-1.666587497	normal	0.340220153	-0.708538284	normal	--	--	--	--	--	--	--	C2 domain	C2 calcium-dependent domain-containing protein 4C GN=C2CD4C OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: C2 calcium-dependent domain-containing protein 4C [Tursiops truncatus]
ENSG00000183196(CHST6)	--	0.78522989	84	0.4834893	43	0.282057245	35	0.3030789	33	0.6180632	89	0.30370184	38	0.005348783	-1.338288469	down	0.120393403	1.003026417	normal	0.981847162	0.105958253	normal	0.986272296	-0.039105926	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K09671|0|hsa:4166|CHST6, MCDC1; carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6; K09671 carbohydrate 6-sulfotransferase 6 [EC:2.8.2.-] (A)"	Glycosaminoglycan biosynthesis - keratan sulfate (ko00533)	--	--	Sulfotransferase domain;; Sulfotransferase family	Carbohydrate sulfotransferase 6 GN=CHST6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: carbohydrate sulfotransferase 6 [Ailuropoda melanoleuca] 
ENSG00000183207(RUVBL2)	--	76.598006	2955	69.05285108	2800	78.40698863	3144	78.76666048	3081	79.74190347	3068	60.00256791	2387	0.990107844	0.029393321	normal	0.987019056	0.110388128	normal	0.772956777	-0.405469523	normal	0.727756269	-0.081782869	normal	[K]	Transcription	Molecular Function: DNA helicase activity (GO:0003678);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA replication (GO:0006260);; 	K11338|0|pps:100990812|RUVBL2; RuvB-like AAA ATPase 2; K11338 RuvB-like protein 2 [EC:3.6.4.12] (A)	--	[K]	Transcription	"TIP49 C-terminus;; ATPase family associated with various cellular activities (AAA);; DnaB-like helicase C terminal domain;; Holliday junction DNA helicase ruvB N-terminus;; AAA domain (dynein-related subfamily);; Sigma-54 interaction domain;; Magnesium chelatase, subunit ChlI"	RuvB-like 2 GN=RUVBL2 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: ruvB-like 2 isoform X1 [Myotis davidii] 
ENSG00000183208(GDPGP1)	--	7.067007	156	6.808359	157	3.851947	109	5.898595627	158	4.016947	103	5.9321077	138	0.96764309	-0.012333041	normal	0.485352009	-0.622091433	normal	0.923414339	0.327995631	normal	0.84844474	-0.103272507	normal	--	--	--	"K15630|0|hsa:390637|GDPGP1, C15orf58, VTC2; GDP-D-glucose phosphorylase 1 (EC:2.7.7.78); K15630 GDP-D-glucose phosphorylase [EC:2.7.7.78] (A)"	--	[R]	General function prediction only	--	GDP-D-glucose phosphorylase 1 GN=GDPGP1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: GDP-D-glucose phosphorylase 1 [Camelus bactrianus] 
ENSG00000183246(RIMBP3C)	--	0.00869332	1	0.00849624	1	0.007938127	0	0.034929	4	0.00815147	0	0.00828781	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Variant SH3 domain;; Variant SH3 domain;; SH3 domain	RIMS-binding protein 3C GN=RIMBP3C OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: RIMS-binding protein 3A [Equus caballus]
ENSG00000183248(PRR36)	--	3.087489674	196	2.823956066	176	3.542601521	234	0.86667768	53	1.036013232	63	0.611450602	35	4.21E-11	-1.887103728	down	1.05E-06	-1.481357149	down	0	-2.697441456	down	3.00E-12	-2.026412825	down	--	--	--	--	--	--	--	Domain of unknown function (DUF4596)	Putative uncharacterized protein FLJ22184 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC101367497 [Odobenus rosmarus divergens]
ENSG00000183251(OR51B4)	--	0	0	0	0	0	0	0.0978116	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:79339|OR51B4, HOR5'Beta1; olfactory receptor, family 51, subfamily B, member 4; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 51B4 GN=OR51B4 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	olfactory receptor 51B4 [Oryctolagus cuniculus] 
ENSG00000183255(PTTG1IP)	--	74.54055719	3418	68.03611305	3160	70.91836669	3293	86.8110008	4002	81.54138316	3730	92.28648337	4253	0.98171574	0.196654751	normal	0.976982918	0.217728518	normal	0.892105044	0.360640786	normal	0.132770327	0.258938268	normal	--	--	--	--	--	--	--	--	Pituitary tumor-transforming gene 1 protein-interacting protein (Precursor) GN=PTTG1IP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pituitary tumor-transforming gene 1 protein-interacting protein [Galeopterus variegatus]
ENSG00000183258(DDX41)	--	25.805092	1005	23.8064	1007	22.5905	947	25.909304	1086	23.270494	1061	26.385676	994	0.977546425	0.080877382	normal	0.978402465	0.053855619	normal	0.977820114	0.061494125	normal	0.804889679	0.064563676	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: zinc ion binding (GO:0008270);; 	K13116|0|pps:100967598|DDX41; DEAD (Asp-Glu-Ala-Asp) box polypeptide 41; K13116 ATP-dependent RNA helicase DDX41 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Probable ATP-dependent RNA helicase DDX41 GN=DDX41 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX41 [Orycteropus afer afer]
ENSG00000183260(ABHD16B)	--	4.04455	78	5.44425	110	6.5908	135	4.4326	87	3.84074	75	3.77036	74	0.970136233	0.124388365	normal	0.762118956	-0.564508843	normal	0.090866986	-0.862409969	normal	0.265799748	-0.473852466	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Abhydrolase domain-containing protein 16B GN=ABHD16B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: abhydrolase domain-containing protein 16B [Oryctolagus cuniculus]
ENSG00000183281(PLGLB1)	--	1.054445	19	0.8669185	14	0.92503	17	0.82964	15	0.4861721	9	0.3532095	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PAN domain	Plasminogen-like protein B (Precursor) GN=PLGLB2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: plasminogen [Galeopterus variegatus]
ENSG00000183283(DAZAP2)	--	204.34036	3239	208.802862	3606	186.342431	3041	260.480728	3948	275.699782	4073	253.282511	3732	0.968341967	0.254631715	normal	0.986615759	0.154204982	normal	0.953437522	0.286982687	normal	0.198617048	0.228016265	normal	--	--	--	--	--	--	--	DAZ associated protein 2 (DAZAP2)	DAZ-associated protein 2 GN=DAZAP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DAZ-associated protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000183287(CCBE1)	--	1.323856321	152	1.017470322	115	1.323720055	157	9.494327501	1063	9.786685877	902	5.400471964	542	0	2.762916269	up	0	2.933792514	up	2.22E-16	1.769477611	up	2.56E-06	2.541146908	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Collagen triple helix repeat (20 copies);; Calcium-binding EGF domain;; Coagulation Factor Xa inhibitory site;; Complement Clr-like EGF-like;; EGF-like domain	Collagen and calcium-binding EGF domain-containing protein 1 (Precursor) GN=CCBE1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: collagen and calcium-binding EGF domain-containing protein 1 [Tupaia chinensis]
ENSG00000183291(SELENOF)	--	83.45999922	1841	88.79413323	1944	81.57967306	1776	89.40440079	1957	89.90299322	1958	94.0151	2065	0.985488211	0.057275502	normal	0.986267893	-0.011065435	normal	0.968549951	0.209053528	normal	0.720524947	0.083644756	normal	--	--	--	--	--	[R]	General function prediction only	--	15 kDa selenoprotein (Precursor) GN=SEP15 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: 15 kDa selenoprotein [Ursus maritimus]
ENSG00000183307(CECR6)	--	0.251088877	19	0.2042161	15	0.2500381	16	0.065757664	5	0.031291774	1	0.095514104	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CECR6/TMEM121 family	Cat eye syndrome critical region protein 6 GN=CECR6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: cat eye syndrome critical region protein 6 [Ceratotherium simum simum]
ENSG00000183309(ZNF623)	--	10.6006321	1033	10.81615314	1007	10.516713	939	10.0363445	937	11.6019173	1042	12.74792678	1198	0.965207553	-0.171283923	normal	0.979086843	0.027823959	normal	0.850712079	0.342649689	normal	0.781254134	0.072252807	normal	[R]	General function prediction only	--	K09228|0|ggo:101154617|ZNF623; zinc finger protein 623 isoform 1; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Transposase zinc-ribbon domain;; Double zinc ribbon;; Probable zinc-binding domain"	Zinc finger protein 623 GN=ZNF623 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 623 [Ceratotherium simum simum]
ENSG00000183317(EPHA10)	--	1.414508289	128	1.427849736	134	1.247178012	130	0.9561562	78	1.179435507	109	0.623742458	57	0.32934673	-0.734021464	normal	0.926991172	-0.315377282	normal	0.001991766	-1.176522684	down	0.048852221	-0.705715486	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08897|0|hsa:284656|EPHA10; EPH receptor A10 (EC:2.7.10.1); K08897 Eph receptor A10 [EC:2.7.10.1] (A)	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Ephrin type-A receptor 2 transmembrane domain	Ephrin type-A receptor 10 (Precursor) GN=EPHA10 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: ephrin type-A receptor 10 [Orcinus orca]
ENSG00000183323(CCDC125)	--	4.835149354	308	5.903594624	371	4.389819363	296	4.815816348	273	3.572446035	235	4.46179705	272	0.94485896	-0.20378105	normal	0.066232933	-0.676687437	normal	0.959851199	-0.129591053	normal	0.18214006	-0.343476393	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 125 GN=CCDC125 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 125 isoform X1 [Galeopterus variegatus]
ENSG00000183336(BOLA2)	--	31.3893	376	27.1042	324	28.1169	337	30.2782	372	30.8816	370	24.2165	292	0.968225594	-0.046073025	normal	0.952617779	0.169364746	normal	0.941658649	-0.214038862	normal	0.956980171	-0.026054497	normal	[T]	Signal transduction mechanisms	--	--	--	[T]	Signal transduction mechanisms	BolA-like protein	BolA-like protein 2 GN=BOLA2B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: bolA-like protein 2 [Ailuropoda melanoleuca]
ENSG00000183337(BCOR)	--	9.577143467	1330	8.69737045	1188	9.659560154	1270	12.5857214	1578	11.8738793	1612	9.549837158	1290	0.960999447	0.215609823	normal	0.6902191	0.418431492	normal	0.982324096	0.014234309	normal	0.22165001	0.220386974	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies)	BCL-6 corepressor GN=BCOR OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: BCL-6 corepressor isoform X1 [Galeopterus variegatus]
ENSG00000183340(JRKL)	--	6.13245	304	6.90375	345	5.93799	290	6.35254	319	6.18545	305	7.0184	347	0.967354256	0.038463067	normal	0.945332678	-0.198288546	normal	0.927858368	0.24940088	normal	0.955958996	0.027158093	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; Tc5 transposase DNA-binding domain;; CENP-B N-terminal DNA-binding domain	Jerky protein homolog-like GN=JRKL OS=Homo sapiens (Human) PE=2 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: jerky protein homolog-like [Odobenus rosmarus divergens] 
ENSG00000183346(C10orf107)	--	0.291106451	8	3.388000097	1	0.308618	7	0	0	0.125322016	2	0.251130021	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Flagellar C1a complex subunit C1a-32	Uncharacterized protein C10orf107 GN=C10orf107 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C10orf107 homolog isoform X1 [Galeopterus variegatus]
ENSG00000183354(KIAA2026)	--	4.668898428	541	4.963532324	597	5.236850341	622	4.3741289	559	4.692812567	562	5.427417514	658	0.972597796	0.016341769	normal	0.967143661	-0.108304535	normal	0.972150618	0.072709667	normal	0.990396904	-0.00508083	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Bromodomain	Uncharacterized protein KIAA2026 GN=KIAA2026 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA2026 homolog [Orcinus orca]
ENSG00000183386(FHL3)	--	6.417217405	163	4.984356922	127	4.458956955	117	6.504372629	168	7.937332	203	4.4937067	115	0.967418015	0.012639653	normal	0.290978804	0.64905994	normal	0.969252602	-0.032739267	normal	0.645570781	0.23361839	normal	--	--	--	--	--	[TZR]	Signal transduction mechanisms;; Cytoskeleton;; General function prediction only	LIM domain	Four and a half LIM domains protein 3 GN=FHL3 OS=Homo sapiens (Human) PE=1 SV=4	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: four and a half LIM domains protein 3 [Tupaia chinensis] 
ENSG00000183395(PMCH)	--	0.742113	7	0.419539	4	0.206718	1	0.396835	4	0.309249	2	0.916914	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: synaptic transmission (GO:0007268);; Molecular Function: melanin-concentrating hormone activity (GO:0030354);; 	"K05229|1.12044e-119|hsa:5367|PMCH, MCH; pro-melanin-concentrating hormone; K05229 pro-melanin-concentrating hormone (A)"	--	--	--	Pro-melanin-concentrating hormone (Pro-MCH)	Melanin-concentrating hormone (Precursor) GN=PMCH OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	hypothetical protein PANDA_003501 [Ailuropoda melanoleuca]
ENSG00000183397(C19orf71)	--	0.246855	2	1.45926	12	0.349173	2	1.30998	11	0.948286	7	1.55499	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4531)	Uncharacterized protein C19orf71 GN=C19orf71 OS=Homo sapiens (Human) PE=4 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C19orf71 homolog [Tupaia chinensis]
ENSG00000183401(CCDC159)	--	4.63974233	62	2.737738152	48	2.710796733	46	2.336775	28	1.92881155	29	1.7815082	23	0.178162512	-1.134745002	normal	0.874616804	-0.718964639	normal	0.698056565	-0.962699246	normal	0.059694868	-0.985419581	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 159 GN=CCDC159 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 159 [Leptonychotes weddellii]
ENSG00000183421(RIPK4)	--	3.895498515	292	2.580119003	198	2.394009759	184	4.991570605	376	5.945548879	444	4.015889781	302	0.866303784	0.33238741	normal	1.54E-06	1.137678625	up	0.065812839	0.702003184	normal	0.030938656	0.713204662	normal	[R]	General function prediction only	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08848|0|hsa:54101|RIPK4, ANKK2, ANKRD3, DIK, NKRD3, PKK, PPS2, RIP4; receptor-interacting serine-threonine kinase 4 (EC:2.7.11.1); K08848 receptor-interacting serine/threonine-protein kinase 4 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Protein kinase domain;; Protein tyrosine kinase	Receptor-interacting serine/threonine-protein kinase 4 GN=RIPK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: receptor-interacting serine/threonine-protein kinase 4 [Ceratotherium simum simum]
ENSG00000183423(LRIT3)	--	0.017814404	1	0	0	0.071291087	3	0	0	0	0	0.033535911	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Immunoglobulin I-set domain;; Leucine Rich Repeat;; Immunoglobulin domain;; Leucine rich repeat;; Fibronectin type III domain	"Leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 (Precursor) GN=LRIT3 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: leucine-rich repeat, immunoglobulin-like domain and transmembrane domain-containing protein 3 [Leptonychotes weddellii]"
ENSG00000183426(NPIPA1)	--	4.49758661	88	4.055798291	76	3.119452736	59	2.584140043	52	2.965601447	55	3.21640213	56	0.515135512	-0.772078667	normal	0.909965172	-0.476791292	normal	0.976274018	-0.081436724	normal	0.358125618	-0.473641986	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A1 GN=NPIPA1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	--
ENSG00000183431(SF3A3)	--	16.196	1200	16.4768	1225	16.6163	1228	19.8055	1470	22.4722	1653	15.6136	1156	0.939287938	0.261646402	normal	0.717464004	0.410440762	normal	0.978250157	-0.095339571	normal	0.397095737	0.206471701	normal	[A]	RNA processing and modification	--	"K12827|0|ptr:745795|SF3A3; splicing factor 3a, subunit 3, 60kDa; K12827 splicing factor 3A subunit 3 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	Domain of unknown function (DUF3449);; Telomere stability C-terminal;; Splicing factor SF3a60 binding domain	Splicing factor 3A subunit 3 GN=SF3A3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"Type II inositol-1,4,5-trisphosphate 5-phosphatase [Pteropus alecto]"
ENSG00000183439(TRIM61)	--	0	0	0.0389111	1	0.0772283	1	0	0	0	0	0.0389268	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12029|5.4121e-131|hsa:391712|TRIM61, RNF35; tripartite motif containing 61; K12029 tripartite motif-containing protein 60/61 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Ring finger domain"	Putative tripartite motif-containing protein 61 GN=TRIM61 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 60-like [Ceratotherium simum simum]
ENSG00000183454(GRIN2A)	--	0	0	0	0	0.015667221	3	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05209|0|hsa:2903|GRIN2A, EPND, FESD, GluN2A, LKS, NMDAR2A, NR2A; glutamate receptor, ionotropic, N-methyl D-aspartate 2A; K05209 glutamate receptor ionotropic, NMDA 2A (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033);; Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"N-methyl D-aspartate receptor 2B3 C-terminus;; Ligand-gated ion channel;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site;; Receptor family ligand binding region"	"Glutamate receptor ionotropic, NMDA 2A (Precursor) GN=GRIN2A OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, NMDA 2A isoform X1 [Tupaia chinensis]"
ENSG00000183474(GTF2H2C)	--	10.59495776	452	11.715609	482	10.79484447	420	10.15270315	428	10.4057884	435	9.509472829	374	0.964783378	-0.109162832	normal	0.954701604	-0.168886222	normal	0.953026654	-0.174974443	normal	0.585003091	-0.152126271	normal	[KL]	"Transcription;; Replication, recombination and repair"	Biological Process: DNA repair (GO:0006281);; Molecular Function: zinc ion binding (GO:0008270);; 	"K03142|0|hsa:728340|GTF2H2C, GTF2H2C_2; GTF2H2 family member C; K03142 transcription initiation factor TFIIH subunit 2 (A)"	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420);; Viral carcinogenesis (ko05203)	[KL]	"Transcription;; Replication, recombination and repair"	Ssl1-like;; TFIIH C1-like domain;; von Willebrand factor type A domain	General transcription factor IIH subunit 2-like protein GN=GTF2H2C_2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor IIH subunit 2 [Loxodonta africana]
ENSG00000183475(ASB7)	--	7.569756285	584	7.658968171	604	7.292984	560	7.288965172	552	7.9529078	583	7.449473652	553	0.967102686	-0.11182968	normal	0.970597982	-0.072294967	normal	0.972646104	-0.026367134	normal	0.813067828	-0.071654069	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10329|0|umr:103659986|ASB7; ankyrin repeat and SOCS box containing 7; K10329 ankyrin repeat and SOCS box protein 7 (A)	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SOCS box	Ankyrin repeat and SOCS box protein 7 GN=ASB7 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: ankyrin repeat and SOCS box protein 7 [Pantholops hodgsonii]
ENSG00000183476(SH2D7)	--	0.169067	10	0.0844878	5	0.0825153	4	0.0339947	2	0.164486517	9	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	SH2 domain	SH2 domain-containing protein 7 GN=SH2D7 OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	PREDICTED: SH2 domain-containing protein 7 [Ceratotherium simum simum]
ENSG00000183479(TREX2)	--	16.62926028	386	13.49992408	320	17.73015317	414	18.31623326	440	15.8418675	379	13.85943294	336	0.956870839	0.157483016	normal	0.937911141	0.221735576	normal	0.887178575	-0.308208892	normal	0.959389613	0.022701836	normal	--	--	--	K10791|6.70895e-168|mcc:695461|TREX1; three prime repair exonuclease 2-like; K10791 three prime repair exonuclease 2 [EC:3.1.11.2] (A)	--	[L]	"Replication, recombination and repair"	Exonuclease	Three prime repair exonuclease 2 GN=TREX2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: three prime repair exonuclease 2 [Pteropus alecto] 
ENSG00000183484(GPR132)	--	0.353480825	19	0.286249249	17	0.208343308	14	0.046388634	1	0.321338677	10	0.250165158	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08426|0|hsa:29933|GPR132, G2A; G protein-coupled receptor 132; K08426 G protein-coupled receptor 132 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 132 GN=GPR132 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 132 [Galeopterus variegatus]
ENSG00000183486(MX2)	--	0.094676231	6	0.062640834	4	0	0	0.09450939	6	0.107056422	6	0.031230931	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Dynamin central region;; Dynamin family;; Dynamin GTPase effector domain	Interferon-induced GTP-binding protein Mx2 GN=MX2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: interferon-induced GTP-binding protein Mx2 [Galeopterus variegatus]
ENSG00000183495(EP400)	--	15.207919	3433	14.98021913	3542	16.088182	3651	15.763053	3542	15.796162	3762	16.38007291	3988	0.991257987	0.01425581	normal	0.990556359	0.065481949	normal	0.989123803	0.119035109	normal	0.788761777	0.06695561	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K11320|0|hsa:57634|EP400, CAGH32, P400, TNRC12; E1A binding protein p400; K11320 E1A-binding protein p400 [EC:3.6.4.-] (A)"	--	[R]	General function prediction only	SNF2 family N-terminal domain;; HSA;; Helicase conserved C-terminal domain	E1A-binding protein p400 GN=EP400 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: E1A-binding protein p400 [Oryctolagus cuniculus]
ENSG00000183496(MEX3B)	--	2.868052269	166	4.276443	249	3.511509484	210	3.698286	220	4.728603	278	4.949437	291	0.861125264	0.372485048	normal	0.957638337	0.136726414	normal	0.675691068	0.459515383	normal	0.306430221	0.315789594	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: metal ion binding (GO:0046872);; 	"K15686|0|hsa:84206|MEX3B, MEX-3B, RKHD3, RNF195; mex-3 RNA binding family member B; K15686 RNA-binding protein MEX3 (A)"	--	[R]	General function prediction only	"KH domain;; KH domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RNA-binding protein MEX3B GN=MEX3B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RNA-binding protein MEX3B isoform X2 [Lipotes vexillifer]
ENSG00000183508(FAM46C)	--	0.104806	10	0.103538	10	0.0518105	4	0.0415783	4	0.0814619	7	0.0208121	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF1693)	Protein FAM46C GN=FAM46C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM46C isoform X1 [Mustela putorius furo] 
ENSG00000183513(COA5)	--	12.74501	335	10.58920042	303	14.17858	377	7.66553	196	6.939252	184	8.24826	217	0.008904752	-0.799285773	normal	0.040047331	-0.736271711	normal	0.006243367	-0.80087191	normal	0.000361237	-0.786268635	normal	--	--	--	K18178|8.83827e-47|ptr:100612731|COA5; cytochrome c oxidase assembly factor 5; K18178 cytochrome c oxidase assembly factor 5 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cytochrome c oxidase assembly protein PET191	Cytochrome c oxidase assembly factor 5 GN=COA5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cytochrome c oxidase assembly factor 5-like [Tupaia chinensis]
ENSG00000183520(UTP11)	--	15.91189	521	14.67697	477	16.544858	532	17.34213	575	17.43037	569	14.61892	482	0.966760766	0.111134284	normal	0.935869167	0.232337684	normal	0.960276542	-0.150235669	normal	0.833159217	0.066257768	normal	[S]	Function unknown	Biological Process: rRNA processing (GO:0006364);; Cellular Component: small-subunit processome (GO:0032040);; 	"K14769|2.25369e-171|hsa:51118|UTP11L, CGI94; UTP11-like, U3 small nucleolar ribonucleoprotein (yeast); K14769 U3 small nucleolar RNA-associated protein 11 (A)"	--	[S]	Function unknown	Utp11 protein	Probable U3 small nucleolar RNA-associated protein 11 GN=UTP11L OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable U3 small nucleolar RNA-associated protein 11 [Galeopterus variegatus]
ENSG00000183527(PSMG1)	--	18.787562	492	22.564781	542	18.186044	449	25.384091	616	21.129149	540	20.556875	496	0.898205721	0.292621722	normal	0.971582074	-0.026685408	normal	0.962141471	0.134900778	normal	0.614411852	0.133562664	normal	--	--	Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: proteasome assembly (GO:0043248);; 	"K11875|0|pps:100996135|PSMG1; proteasome (prosome, macropain) assembly chaperone 1; K11875 proteasome assembly chaperone 1 (A)"	--	--	--	--	Proteasome assembly chaperone 1 GN=PSMG1 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome assembly chaperone 1 isoform X1 [Galeopterus variegatus]
ENSG00000183530(PRR14L)	--	3.796997	840	4.626421	991	3.828446004	810	5.123373	1095	4.506253	991	4.4795764	980	0.832531163	0.351073574	normal	0.97881146	-0.021393911	normal	0.926516397	0.26611606	normal	0.331760229	0.193471866	normal	--	--	--	--	--	--	--	Drosophila Tantalus-like	Protein PRR14L GN=PRR14L OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein PRR14L [Galeopterus variegatus]
ENSG00000183542(KLRC4)	--	0	0	0.0782225	1	0	0	0.0762995	1	0.0760184	0	0.154353	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06541|1.64255e-114|hsa:8302|KLRC4, NKG2-F, NKG2F; killer cell lectin-like receptor subfamily C, member 4; K06541 killer cell lectin-like receptor subfamily C (A)"	Antigen processing and presentation (ko04612)	--	--	--	NKG2-F type II integral membrane protein GN=KLRC4 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: NKG2-A/NKG2-B type II integral membrane protein [Lipotes vexillifer]
ENSG00000183549(ACSM5)	--	0.051306129	1	0	0	0	0	0	0	0	0	0.03451	2	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	K01896|0|hsa:54988|ACSM5; acyl-CoA synthetase medium-chain family member 5 (EC:6.2.1.2); K01896 medium-chain acyl-CoA synthetase [EC:6.2.1.2] (A)	Butanoate metabolism (ko00650)	[I]	Lipid transport and metabolism	AMP-binding enzyme;; AMP-binding enzyme C-terminal domain	"Acyl-coenzyme A synthetase ACSM5, mitochondrial (Precursor) GN=ACSM5 OS=Homo sapiens (Human) PE=2 SV=2"	I	Lipid transport and metabolism	"PREDICTED: acyl-coenzyme A synthetase ACSM5, mitochondrial [Equus caballus]"
ENSG00000183569(SERHL2)	--	1.0357497	24	0.706526739	16	1.030072939	23	0.391652708	9	0.430500301	9	0.5423021	13	0.816850413	-1.304824932	normal	--	--	--	0.965525219	-0.763833837	normal	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Alpha/beta hydrolase family;; alpha/beta hydrolase fold;; Alpha/beta hydrolase family	Serine hydrolase-like protein 2 GN=SERHL2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: serine hydrolase-like protein-like [Ceratotherium simum simum]
ENSG00000183570(PCBP3)	--	0.756766422	30	0.177582772	7	0.118997555	4	0	0	0.14108253	5	0.10629703	4	6.02E-06	-4.374068103	down	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: RNA binding (GO:0003723);; 	K13162|0|mcf:101925063|uncharacterized LOC101925063; K13162 poly(rC)-binding protein 2/3/4 (A)	--	[AR]	RNA processing and modification;; General function prediction only	KH domain;; KH domain;; KH domain;; KH domain	Poly(rC)-binding protein 3 GN=PCBP3 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: poly(rC)-binding protein 3 isoform X2 [Galeopterus variegatus]
ENSG00000183576(SETD3)	--	28.03111119	1450	26.92835864	1365	28.0657346	1371	26.5871301	1387	27.45053661	1377	20.1335469	1024	0.980399717	-0.094814638	normal	0.982666063	-0.008789255	normal	0.630124591	-0.428755047	normal	0.419912366	-0.16616563	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Rubisco LSMT substrate-binding;; SET domain	Histone-lysine N-methyltransferase setd3 GN=SETD3 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase setd3 [Ceratotherium simum simum]
ENSG00000183578(TNFAIP8L3)	--	0.714966165	25	0.540717958	19	1.121554742	41	2.328799983	83	2.091274811	77	3.382440035	125	0.00026728	1.641937771	up	2.98E-05	1.915999764	up	9.82E-06	1.56523129	up	0.000326889	1.726696586	up	--	--	--	--	--	--	--	Domain of unknown function (DUF758)	Tumor necrosis factor alpha-induced protein 8-like protein 3 GN=TNFAIP8L3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: tumor necrosis factor alpha-induced protein 8-like protein 3 [Vicugna pacos]
ENSG00000183579(ZNRF3)	--	10.02565289	1192	8.289731587	947	8.681884064	985	4.458412	489	4.828276891	575	3.794126617	456	7.23E-12	-1.313574461	down	0.004034318	-0.739696478	normal	3.56E-08	-1.116797911	down	1.44E-09	-1.060701863	down	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metal ion binding (GO:0046872);; 	"K16273|0|hsa:84133|ZNRF3, BK747E2.3, RNF203; zinc and ring finger 3; K16273 E3 ubiquitin-protein ligase ZNRF3 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase ZNRF3 (Precursor) GN=ZNRF3 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase ZNRF3 [Pteropus alecto]
ENSG00000183580(FBXL7)	--	1.362344039	107	1.310019131	103	1.783235048	121	1.0083178	77	1.465372896	93	1.314409942	100	0.848034527	-0.497057646	normal	0.962881042	-0.166198877	normal	0.943948052	-0.279450589	normal	0.501821407	-0.313983707	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10273|0|ptr:471460|FBXL7; F-box and leucine-rich repeat protein 7; K10273 F-box and leucine-rich repeat protein 7 (A)	--	[R]	General function prediction only	Leucine Rich repeat;; F-box-like;; Leucine Rich Repeat;; Leucine Rich repeats (2 copies);; F-box domain;; Leucine rich repeat;; Leucine rich repeat	F-box/LRR-repeat protein 7 GN=FBXL7 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: F-box/LRR-repeat protein 7 [Equus przewalskii]
ENSG00000183597(TANGO2)	--	9.18462404	447	8.53042194	392	9.221834786	500	8.833875706	434	9.715756745	445	9.564122972	493	0.968072845	-0.073156838	normal	0.955565279	0.160942089	normal	0.971413917	-0.028544942	normal	0.976887251	0.014662637	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	NRDE protein	Transport and Golgi organization protein 2 homolog GN=TANGO2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transport and Golgi organization protein 2 homolog isoform X1 [Galeopterus variegatus]
ENSG00000183598(HIST2H3D)	--	2.5690952	107	3.069538902	71	1.739661	110	1.6613044	72	2.978555	62	2.4741247	125	0.736018277	-0.591939962	normal	0.966458726	-0.212137793	normal	0.960648156	0.17388916	normal	0.82445739	-0.172166612	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	--	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.2 GN=HIST2H3D OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H3.2-like [Sarcophilus harrisii]
ENSG00000183605(SFXN4)	--	27.02318471	576	22.8975288	500	29.15231619	611	22.47865167	501	21.331669	457	21.1294	457	0.936742439	-0.231427869	normal	0.958808169	-0.15068357	normal	0.654146546	-0.426045921	normal	0.205721507	-0.274890065	normal	--	--	Biological Process: ion transport (GO:0006811);; Molecular Function: ion transmembrane transporter activity (GO:0015075);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Tricarboxylate carrier	Sideroflexin-4 GN=SFXN4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sideroflexin-4 isoform X1 [Oryctolagus cuniculus]
ENSG00000183607(GKN2)	--	0	0	0	0	0	0	0	0	0.191802551	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	BRICHOS domain	Gastrokine-2 (Precursor) GN=GKN2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: gastrokine-2 [Elephantulus edwardii]
ENSG00000183615(FAM167B)	--	1.14461	16	0.898005	13	0.201488	2	0.564001	8	0.905483	12	1.12614	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF3259)	Protein FAM167B GN=FAM167B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM167B [Trichechus manatus latirostris]
ENSG00000183617(MRPL54)	--	23.6517	180	25.9037	204	25.064121	197	24.9106	200	26.0004	198	24.6006	192	0.96152652	0.120197251	normal	0.964260972	-0.064013572	normal	0.96629784	-0.045030594	normal	1	0.000893179	normal	--	--	--	"K17435|4.45468e-97|hsa:116541|MRPL54, L54mt, MRP-L54; mitochondrial ribosomal protein L54; K17435 large subunit ribosomal protein L54 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal protein L37	"39S ribosomal protein L54, mitochondrial (Precursor) GN=MRPL54 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L54, mitochondrial [Tupaia chinensis] "
ENSG00000183621(ZNF438)	--	2.358333115	158	2.121691965	137	1.765563488	114	1.447685024	89	1.640572321	113	1.424062651	96	0.058954989	-0.84773743	normal	0.932541518	-0.295679659	normal	0.951403366	-0.252563266	normal	0.205203664	-0.478062439	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Zinc-finger double domain	Zinc finger protein 438 GN=ZNF438 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 438 [Ceratotherium simum simum]
ENSG00000183624(HMCES)	--	23.77154431	843	24.75469347	825	23.23674309	834	20.0981389	678	22.40680726	823	19.67492528	667	0.838305097	-0.344378102	normal	0.97653595	-0.02488258	normal	0.860492972	-0.329981527	normal	0.253357537	-0.227839933	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	"Uncharacterised ACR, COG2135"	Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein GN=HMCES OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein isoform X1 [Eptesicus fuscus]
ENSG00000183628(DGCR6)	--	2.77441205	71	2.482257475	65	2.736019181	71	3.449046959	90	3.95291444	101	4.739550018	123	0.951027829	0.30539312	normal	0.74516943	0.603079112	normal	0.2816801	0.771836095	normal	0.165648091	0.580982195	normal	--	--	--	--	--	[S]	Function unknown	DiGeorge syndrome critical region 6 (DGCR6) protein	Protein DGCR6 GN=DGCR6 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein DGCR6-like [Galeopterus variegatus]
ENSG00000183638(RP1L1)	--	0.0453295	10	0.00878702	2	0	0	0.00904721	2	0.00881959	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	Doublecortin	Retinitis pigmentosa 1-like 1 protein GN=RP1L1 OS=Homo sapiens (Human) PE=1 SV=4	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: LOW QUALITY PROTEIN: retinitis pigmentosa 1-like 1 [Equus caballus]
ENSG00000183644(C11orf88)	--	0	0	0	0	0	0	0.093820405	1	0.0425298	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	UPF0722 protein C11orf88 GN=C11orf88 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: UPF0722 protein C11orf88 homolog isoform X1 [Oryctolagus cuniculus]
ENSG00000183647(ZNF530)	--	7.64908035	223	4.187507259	165	4.565972856	192	5.0434753	205	2.721241059	137	4.661916587	208	0.957154393	-0.151165329	normal	0.928076523	-0.286826969	normal	0.962609742	0.106380561	normal	0.833277129	-0.097900078	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:348327|ZNF530; zinc finger protein 530; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Transcription factor S-II (TFIIS)"	Zinc finger protein 530 GN=ZNF530 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 530-like [Ceratotherium simum simum]
ENSG00000183648(NDUFB1)	--	261.931508	266	295.736422	315	257.058004	282	308.21698	380	252.534232	260	246.6790959	272	0.552783471	0.481403731	normal	0.901660622	-0.29669619	normal	0.966001231	-0.060052022	normal	0.895327936	0.057206005	normal	--	--	Molecular Function: NADH dehydrogenase activity (GO:0003954);; Cellular Component: mitochondrion (GO:0005739);; 	"K03957|1.74425e-58|ptr:453115|NDUFB1; NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa; K03957 NADH dehydrogenase (ubiquinone) 1 beta subcomplex subunit 1 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	MNLL subunit	NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 GN=NDUFB1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 [Galeopterus variegatus]
ENSG00000183655(KLHL25)	--	3.517071	265	3.214111736	248	3.323218861	258	4.056584712	307	4.22441	311	2.744935	206	0.950827631	0.180441444	normal	0.897761025	0.303492265	normal	0.885233092	-0.330843153	normal	0.85524416	0.073728054	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10462|0|pps:100991972|KLHL25; kelch-like family member 25; K10462 kelch-like protein 25/37 (ectoderm-neural cortex protein) (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; BTB/POZ domain;; Kelch motif;; Kelch motif"	Kelch-like protein 25 GN=KLHL25 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ectoderm-neural cortex protein 2 [Mustela putorius furo] 
ENSG00000183668(PSG9)	--	0	0	0	0	0	0	0	0	0.037177852	0	0.151192625	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06500|0|ptr:741605|PSG9; pregnancy specific beta-1-glycoprotein 9; K06500 pregnancy specific beta-1-glycoprotein (A)	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Pregnancy-specific beta-1-glycoprotein 9 (Precursor) GN=PSG9 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1-like [Panthera tigris altaica]
ENSG00000183671(GPR1)	--	0.290322573	6	0.111607259	3	0	0	0.896266901	10	0.914820619	18	0.352978885	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04310|0|mcc:707120|GPR1; G protein-coupled receptor 1; K04310 G protein-coupled receptor 1 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 1 GN=GPR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 1 [Galeopterus variegatus] 
ENSG00000183682(BMP8A)	--	0.503057	28	0.1252956	6	0.3584692	18	0.0720089	4	0.342579	16	0.0708577	4	0.015527289	-2.441215346	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: growth factor activity (GO:0008083);; 	K16622|0|hsa:353500|BMP8A; bone morphogenetic protein 8a; K16622 bone morphogenetic protein 8 (A)	TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390)	[T]	Signal transduction mechanisms	TGF-beta propeptide;; Transforming growth factor beta like domain	Bone morphogenetic protein 8A (Precursor) GN=BMP8A OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein 8B [Sus scrofa]
ENSG00000183684(ALYREF)	--	112.022	2005	118.457	2238	128.198	2434	147.1	2757	131.328	2359	110.946	2022	0.682157355	0.428383801	normal	0.987067869	0.054502951	normal	0.946735308	-0.275649422	normal	0.800546347	0.074414037	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12881|2.17458e-86|hsa:10189|ALYREF, ALY, ALY/REF, BEF, REF, THOC4; Aly/REF export factor; K12881 THO complex subunit 4 (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; C-terminal duplication domain of Friend of PRMT1"	THO complex subunit 4 GN=ALYREF OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	THO complex subunit 4 [Bos taurus] 
ENSG00000183688(RFLNB)	--	18.8989	1195	14.5985	929	18.0104	1142	12.3848	783	15.6397	986	8.80577	558	0.027269017	-0.639734223	normal	0.976968498	0.064380758	normal	3.18E-07	-1.039504901	down	0.097156012	-0.510739397	normal	--	--	Molecular Function: filamin binding (GO:0031005);; Biological Process: regulation of chondrocyte development (GO:0061181);; Biological Process: actin filament bundle organization (GO:0061572);; 	--	--	--	--	FAM101 family	Filamin-interacting protein FAM101B GN=FAM101B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM101B [Panthera tigris altaica]
ENSG00000183690(EFHC2)	--	0.341848	15	0.344093	15	0.388231	16	0.27146	12	0.640561	28	0.316731	14	--	--	--	0.940436035	0.817879456	normal	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Repeat of unknown function (DUF1126)	EF-hand domain-containing family member C2 GN=EFHC2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: EF-hand domain-containing family member C2 [Galeopterus variegatus]
ENSG00000183691(NOG)	--	0.546608	15	0.773093	22	0.136271	3	0.898154	25	0.560034	15	0.178122	5	0.971529474	0.653817917	normal	0.97950944	-0.529631346	normal	--	--	--	--	--	--	--	--	--	K04658|5.68093e-132|ptr:468413|NOG; noggin; K04658 noggin (A)	TGF-beta signaling pathway (ko04350)	--	--	Noggin	Noggin (Precursor) GN=NOG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: noggin [Oryctolagus cuniculus]
ENSG00000183696(UPP1)	--	38.92117466	860	44.51055026	990	43.43316993	979	23.76326755	510	20.4826098	448	29.72180353	652	0.001245412	-0.782833226	normal	1.12E-08	-1.16264427	down	0.080512742	-0.593596801	normal	2.79E-07	-0.833657534	normal	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: nucleoside metabolic process (GO:0009116);; 	K00757|0|ptr:472361|UPP1; uridine phosphorylase 1; K00757 uridine phosphorylase [EC:2.4.2.3] (A)	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	Phosphorylase superfamily	Uridine phosphorylase 1 GN=UPP1 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: uridine phosphorylase 1 isoform X2 [Galeopterus variegatus] 
ENSG00000183718(TRIM52)	--	4.80513	331	4.63962	321	5.12418	351	5.76651	398	4.65879	318	5.03073	345	0.933743367	0.234112867	normal	0.966698908	-0.03480833	normal	0.968277307	-0.033022598	normal	0.877071809	0.059525302	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12025|4.22373e-158|hsa:84851|TRIM52, RNF102; tripartite motif containing 52; K12025 tripartite motif-containing protein 52 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; RING-type zinc-finger;; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 52 GN=TRIM52 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 52 isoform X3 [Ursus maritimus]
ENSG00000183722(LHFP)	--	5.816722334	231	5.258152	209	6.305316	250	8.2433	325	5.285314	207	6.273169	248	0.653577568	0.459129246	normal	0.965351183	-0.035043939	normal	0.967034231	-0.019759407	normal	0.690568176	0.154889244	normal	--	--	--	--	--	[S]	Function unknown	Lipoma HMGIC fusion partner-like protein;; Uncharacterized protein family UPF0016	Lipoma HMGIC fusion partner (Precursor) GN=LHFP OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: lipoma HMGIC fusion partner [Tupaia chinensis]
ENSG00000183723(CMTM4)	--	21.18056301	2656	19.15589257	2449	20.43302433	2492	21.47824678	2704	20.081829	2487	18.2438199	2289	0.98937309	-0.004989398	normal	0.988396952	0.000786694	normal	0.983776037	-0.130795201	normal	0.871889951	-0.044112279	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[V]	Defense mechanisms	Membrane-associating domain	CKLF-like MARVEL transmembrane domain-containing protein 4 GN=CMTM4 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: CKLF-like MARVEL transmembrane domain-containing protein 4 isoform X1 [Bubalus bubalis]
ENSG00000183726(TMEM50A)	--	31.06618	1263	34.1675	1382	29.54758	1193	39.9989	1649	34.70640834	1423	40.6042158	1679	0.845215848	0.353527186	normal	0.982801391	0.020729135	normal	0.403440332	0.484196934	normal	0.08686361	0.286473407	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised protein family (UPF0220)	Transmembrane protein 50A GN=TMEM50A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 50A isoform X1 [Pteropus alecto] 
ENSG00000183729(NPBWR1)	--	2.068172	98	1.197445	61	1.715953	79	3.90015	201	4.56031	238	3.188115	162	0.00263569	0.994407167	normal	1.75E-12	1.916788201	up	0.005783406	1.013942933	up	6.38E-06	1.314850918	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Molecular Function: G-protein coupled peptide receptor activity (GO:0008528);; Cellular Component: integral component of membrane (GO:0016021);; 	K05268|0|ptr:739992|NPBWR1; neuropeptides B/W receptor 1; K05268 neuropeptides B/W receptor 1 (A)	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srw	Neuropeptides B/W receptor type 1 GN=NPBWR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuropeptides B/W receptor type 1-like [Leptonychotes weddellii]
ENSG00000183734(ASCL2)	--	0.0391759	1	0.0749297	2	0.0361118	0	0	0	0.0750827	1	0.191143	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09067|1.978e-67|hsa:430|ASCL2, ASH2, HASH2, MASH2, bHLHa45; achaete-scute family bHLH transcription factor 2; K09067 achaete-scute complex protein (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Achaete-scute homolog 2 GN=ASCL2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	achaete-scute homolog 2 [Sus scrofa] 
ENSG00000183735(TBK1)	--	14.642298	833	15.37050804	873	16.71960638	934	17.23010858	992	17.30420701	982	18.10280659	1030	0.949510972	0.220817783	normal	0.968198493	0.148072862	normal	0.971796506	0.132653836	normal	0.430543134	0.165419046	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05410|0|hsa:29110|TBK1, NAK, T2K; TANK-binding kinase 1 (EC:2.7.11.1); K05410 TANK-binding kinase 1 [EC:2.7.11.10] (A)"	Ras signaling pathway (ko04014);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase TBK1 GN=TBK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase TBK1 [Tupaia chinensis]
ENSG00000183741(CBX6)	--	28.258306	3012	29.05749087	3118	27.49436553	3071	26.957759	2945	24.06071322	2564	21.292229	2348	0.989359665	-0.063253767	normal	0.938899753	-0.303488606	normal	0.798604032	-0.3953442	normal	0.147268246	-0.249712788	normal	--	--	--	K11453|1.58955e-177|ggo:101132816|CBX6; chromobox protein homolog 6; K11453 chromobox protein 6 (A)	--	[B]	Chromatin structure and dynamics	Chromo (CHRromatin Organisation MOdifier) domain	Chromobox protein homolog 6 GN=CBX6 OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: chromobox protein homolog 6 [Galeopterus variegatus]
ENSG00000183742(MACC1)	--	0	0	0.021084305	2	0.021532776	0	0	0	0.034290019	4	0.021275078	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Variant SH3 domain	Metastasis-associated in colon cancer protein 1 GN=MACC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: metastasis-associated in colon cancer protein 1 [Galeopterus variegatus]
ENSG00000183760(ACP7)	--	0.254059139	14	0.244457019	14	0.199485172	11	0.128545088	7	0.03613516	1	0.104601949	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: acid phosphatase activity (GO:0003993);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[G]	Carbohydrate transport and metabolism	Calcineurin-like phosphoesterase;; Iron/zinc purple acid phosphatase-like protein C	Iron/zinc purple acid phosphatase-like protein (Precursor) GN=PAPL OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: iron/zinc purple acid phosphatase-like protein-like [Condylura cristata]
ENSG00000183762(KREMEN1)	--	5.741527277	697	3.93369835	485	4.4200403	543	2.80708	324	3.096605	372	1.9322482	232	8.88E-08	-1.132241836	down	0.740556839	-0.402670418	normal	1.87E-08	-1.229719214	down	0.002176224	-0.916413942	normal	--	--	--	--	--	[GO]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Kringle domain;; WSC domain;; CUB domain	Kremen protein 1 (Precursor) GN=KREMEN1 OS=Homo sapiens (Human) PE=2 SV=3	GO	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	PREDICTED: kremen protein 1 [Ochotona princeps]
ENSG00000183763(TRAIP)	--	4.444452711	196	4.83123186	216	5.819208001	261	4.084976036	185	3.543679347	162	4.413626306	200	0.962172559	-0.113246691	normal	0.785510701	-0.432950834	normal	0.822404728	-0.389753587	normal	0.315140319	-0.319662025	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K11985|0|hsa:10293|TRAIP, RNF206, TRIP; TRAF interacting protein; K11985 TRAF-interacting protein (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRAIP GN=TRAIP OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: TRAF-interacting protein [Equus caballus]
ENSG00000183765(CHEK2)	--	11.19084766	329	8.538072933	224	9.147166882	231	6.359993963	186	6.791747585	169	7.333847637	188	0.00369402	-0.848272556	normal	0.792225396	-0.424590033	normal	0.909155942	-0.303246962	normal	0.069347293	-0.551328994	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K06641|0|hsa:11200|CHEK2, CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1; checkpoint kinase 2 (EC:2.7.11.1); K06641 serine/threonine-protein kinase Chk2 [EC:2.7.11.1] (A)"	Cell cycle (ko04110);; p53 signaling pathway (ko04115);; HTLV-I infection (ko05166)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase;; FHA domain;; Kinase-like	Serine/threonine-protein kinase Chk2 GN=CHEK2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: serine/threonine-protein kinase Chk2-like isoform 4 [Ceratotherium simum simum]
ENSG00000183770(FOXL2)	--	1.57273	67	0.797163	35	1.62555	73	3.61277	158	4.09845	178	4.0475	177	0.000488564	1.188604179	up	1.61E-13	2.276736034	up	6.59E-05	1.252300933	up	6.23E-07	1.531579644	up	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09405|7.20283e-131|pon:100433989|FOXL2; forkhead box L2; K09405 forkhead box protein L (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein L2 GN=FOXL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	forkhead box protein L2 [Sus scrofa] 
ENSG00000183773(AIFM3)	--	0.949850405	53	1.601768591	72	1.051448	61	0.664922503	44	0.493041937	34	1.572134183	70	0.969757238	-0.290076648	normal	0.152204072	-1.070417074	normal	0.970121078	0.185947875	normal	0.563509026	-0.349619976	normal	[R]	General function prediction only	"Molecular Function: nitrite reductase [NAD(P)H] activity (GO:0008942);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: nitrate assimilation (GO:0042128);; Molecular Function: 2 iron, 2 sulfur cluster binding (GO:0051537);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	[R]	General function prediction only	"Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; Rieske [2Fe-2S] domain;; FAD dependent oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; NAD(P)-binding Rossmann-like domain;; HI0933-like protein;; Rieske-like [2Fe-2S] domain;; Reductase C-terminal;; FAD binding domain;; Lycopene cyclase protein;; FAD binding domain;; FAD-NAD(P)-binding;; TrkA-N domain;; Thi4 family;; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain"	Apoptosis-inducing factor 3 GN=AIFM3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: apoptosis-inducing factor 3 isoform X1 [Tupaia chinensis] 
ENSG00000183775(KCTD16)	--	0.03307329	7	0.105597259	7	0.064648473	5	0.086261174	8	0.042314725	5	0.043209385	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD16 GN=KCTD16 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD16 [Odobenus rosmarus divergens]
ENSG00000183778(B3GALT5)	--	0.409685563	93	0.496139956	103	0.557861009	128	1.080458366	211	1.219913173	277	1.14633752	230	0.000154611	1.138297178	up	8.68E-08	1.392855024	up	0.020297939	0.829783828	normal	1.48E-05	1.127643239	up	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K03877|0|hsa:10317|B3GALT5, B3GalT-V, B3GalTx, B3T5, GLCT5, beta-1,3-GalTase_5, beta-3-Gx-T5, beta3Gal-T5; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5; K03877 beta-1,3-galactosyltransferase 5 [EC:2.4.1.-] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601);; Glycosphingolipid biosynthesis - globo series (ko00603)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"Beta-1,3-galactosyltransferase 5 GN=B3GALT5 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyltransferase 5 [Galeopterus variegatus]"
ENSG00000183779(ZNF703)	--	8.70759	414	10.9899	527	6.07651	298	5.89936	282	7.96632	383	9.89248	480	0.202213525	-0.5821325	normal	0.499732088	-0.480261078	normal	0.038350434	0.676699932	normal	0.843370735	-0.134230964	normal	--	--	--	--	--	--	--	NocA-like zinc-finger protein 1	Zinc finger protein 703 GN=ZNF703 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 703 [Orycteropus afer afer]
ENSG00000183780(SLC35F3)	--	16.47554071	408	11.429	301	16.02201501	400	14.23290115	368	13.16867252	321	10.50414574	291	0.951766355	-0.178985509	normal	0.964822101	0.071037616	normal	0.590176612	-0.465201303	normal	0.483237391	-0.200042597	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15288|0|mcf:101866143|uncharacterized LOC101866143; K15288 solute carrier family 35, member F3/4 (A)"	--	[R]	General function prediction only	EamA-like transporter family;; Multidrug resistance efflux transporter;; Triose-phosphate Transporter family;; Eukaryotic protein of unknown function (DUF914)	Putative thiamine transporter SLC35F3 {ECO:0000305} GN=SLC35F3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: solute carrier family 35 member F3 [Condylura cristata]
ENSG00000183784(C9orf66)	--	0.0871324	4	0.0431083	2	0.0843938	3	0.0214852	1	0.104287	4	0.106618	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf66 GN=C9orf66 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C9orf66 homolog [Pantholops hodgsonii]
ENSG00000183785(TUBA8)	--	0.264594884	8	0.272947986	8	0.165691013	4	0.3976821	11	0.472386424	13	0.22182619	6	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07374|0|pps:100986068|TUBA8; tubulin, alpha 8; K07374 tubulin alpha (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain"	Tubulin alpha-8 chain GN=TUBA8 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin alpha-8 chain [Ochotona princeps]
ENSG00000183791(ELOA3)	--	0	0	0	0	0	0	0.0268601	1	0.025964	0	0.0264704	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Cellular Component: integral component of membrane (GO:0016021);; "	"K15076|0|hsa:162699|TCEB3C, HsT829, TCEB3L2; transcription elongation factor B polypeptide 3C (elongin A3); K15076 transcription elongation factor B, polypeptide 3 (A)"	--	[K]	Transcription	RNA polymerase II transcription factor SIII (Elongin) subunit A;; TFIIS helical bundle-like domain	RNA polymerase II transcription factor SIII subunit A3 GN=TCEB3C OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription elongation factor B polypeptide 3 [Ursus maritimus]
ENSG00000183793(NPIPA5)	--	0.840738525	8	1.032697657	10	0.17996728	1	1.187519132	13	0.541135315	5	0.180482382	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A5 GN=NPIPA5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000183798(EMILIN3)	--	0.749749	60	0.615165	51	0.626894	52	0.472716	38	0.545143	43	0.591935	48	0.853391567	-0.66810584	normal	0.970905363	-0.25920546	normal	0.977300362	-0.120131252	normal	0.576463471	-0.358055568	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	EMI domain	EMILIN-3 (Precursor) GN=EMILIN3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: EMILIN-3 [Oryctolagus cuniculus]
ENSG00000183801(OLFML1)	--	0.09517415	5	0.063913861	3	0.234632673	6	0.039905954	1	0.020842318	0	0.119673326	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Olfactomedin-like domain	Olfactomedin-like protein 1 (Precursor) GN=OLFML1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: olfactomedin-like protein 1 [Galeopterus variegatus]
ENSG00000183807(FAM162B)	--	0.130623	2	0	0	0	0	0	0	0	0	0.193565	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF1075)	Protein FAM162B GN=FAM162B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM162B isoform X2 [Oryctolagus cuniculus]
ENSG00000183808(RBM12B)	--	9.633956628	854	9.244407145	1015	14.75483131	1003	10.08177985	868	9.723646	745	11.05641577	858	0.977782729	-0.007360157	normal	0.494568758	-0.466778658	normal	0.945083546	-0.233182948	normal	0.210928466	-0.238160952	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 12B GN=RBM12B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: RNA-binding protein 12B [Ceratotherium simum simum]
ENSG00000183814(LIN9)	--	4.835862989	257	5.421277014	284	5.558301491	291	4.870787725	244	4.92304889	255	4.348150009	236	0.962410871	-0.105074661	normal	0.950858188	-0.175831552	normal	0.89668089	-0.308738688	normal	0.534127754	-0.199981294	normal	--	--	--	--	--	[BDT]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	DIRP	Protein lin-9 homolog GN=LIN9 OS=Homo sapiens (Human) PE=1 SV=1	BDT	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	PREDICTED: protein lin-9 homolog isoform 1 [Ovis aries] 
ENSG00000183826(BTBD9)	--	2.1776891	238	3.373332725	336	1.97029784	270	2.801605152	376	3.773796189	415	3.104840799	405	0.133424508	0.625700024	normal	0.907404192	0.282079371	normal	0.23459901	0.574028541	normal	0.030538673	0.481789506	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10481|0|ptr:462661|BTBD9; BTB (POZ) domain containing 9; K10481 BTB/POZ domain-containing protein 9 (A)	--	[R]	General function prediction only	BTB/POZ domain;; BTB And C-terminal Kelch;; F5/8 type C domain	BTB/POZ domain-containing protein 9 GN=BTBD9 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 9 [Equus caballus] 
ENSG00000183828(NUDT14)	--	47.79831738	1908	46.16622496	1652	46.14758915	1663	32.86040651	1663	31.11761341	1436	40.32830798	1464	0.961197297	-0.228907623	normal	0.959979083	-0.223364968	normal	0.968815815	-0.191977854	normal	0.228098665	-0.216611578	normal	[LR]	"Replication, recombination and repair;; General function prediction only"	--	"K08077|7.17931e-147|hsa:256281|NUDT14, UGPP, UGPPase; nudix (nucleoside diphosphate linked moiety X)-type motif 14 (EC:3.6.1.45); K08077 UDP-sugar diphosphatase [EC:3.6.1.45] (A)"	--	[R]	General function prediction only	NUDIX domain	Uridine diphosphate glucose pyrophosphatase GN=NUDT14 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: uridine diphosphate glucose pyrophosphatase [Tursiops truncatus]
ENSG00000183831(ANKRD45)	--	0.0792556	2	0.0393427	1	0.0391762	0	0.196798	5	0.463663	11	0.235785	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 45 GN=ANKRD45 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ankyrin repeat domain-containing protein 45 [Canis lupus familiaris]
ENSG00000183833(MAATS1)	--	0.1555245	5	0.0544601	5	0.0979104	8	0.0435467	4	0.14056028	12	0.1515589	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1"	Protein MAATS1 GN=MAATS1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein MAATS1 isoform 1 [Ceratotherium simum simum]
ENSG00000183837(PNMA3)	--	0.112540029	3	0.071841847	2	0.0222931	1	0.162673864	14	0.2639345	19	0.178363	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PNMA	Paraneoplastic antigen Ma3 GN=PNMA3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	paraneoplastic antigen Ma3 [Equus caballus] 
ENSG00000183840(GPR39)	--	6.39326	282	6.630712	246	6.220424	266	4.203546	166	3.706758	182	5.013701	182	0.018286421	-0.789666453	normal	0.726062177	-0.452896295	normal	0.436334101	-0.551962333	normal	0.018477949	-0.60398991	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08412|0|hsa:2863|GPR39; G protein-coupled receptor 39; K08412 G protein-coupled receptor 39 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 39 GN=GPR39 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 39 [Ceratotherium simum simum]
ENSG00000183850(ZNF730)	--	0	0	0	0	0	0	0	0	0	0	0.0471013	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:100129543|ZNF730; zinc finger protein 730; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; C1-like domain;; Prephenate dehydratase"	Putative zinc finger protein 730 GN=ZNF730 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000183853(KIRREL)	--	23.21856	3148	27.8044995	3665	25.61338	3295	40.8713518	5467	41.357838	5234	43.73051	5662	0.000813825	0.765194849	normal	0.506087053	0.492503291	normal	0.000653769	0.772468141	normal	2.35E-06	0.673742793	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C1-set domain	Kin of IRRE-like protein 1 (Precursor) GN=KIRREL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kin of IRRE-like protein 1 isoform X1 [Ochotona princeps]
ENSG00000183856(IQGAP3)	--	10.04755939	1353	9.929914333	1339	11.96431682	1625	14.54933228	1932	10.11599592	1349	13.302816	1782	0.415636748	0.482640208	normal	0.982435846	-0.010680153	normal	0.980255752	0.124655362	normal	0.478938188	0.208706437	normal	[DT]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms"	Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of GTPase activity (GO:0043087);; 	K05767|0|hsa:128239|IQGAP3; IQ motif containing GTPase activating protein 3; K05767 Ras GTPase-activating-like protein IQGAP2/3 (A)	Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; RasGAP C-terminus;; IQ calmodulin-binding motif;; Calponin homology (CH) domain	Ras GTPase-activating-like protein IQGAP3 GN=IQGAP3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: IQ motif containing GTPase activating protein 3 isoform X2 [Equus caballus]
ENSG00000183864(TOB2)	--	13.98031	977	11.95201935	995	13.758014	1077	14.01943036	1022	14.28688126	1141	14.139141	1091	0.979107182	0.034080064	normal	0.965333421	0.175854062	normal	0.980501069	0.010327002	normal	0.776500535	0.073083189	normal	--	--	--	"K14443|2.53347e-156|hsa:10766|TOB2, TOB4, TOBL, TROB2; transducer of ERBB2, 2; K14443 protein Tob/BTG (A)"	RNA degradation (ko03018)	[TR]	Signal transduction mechanisms;; General function prediction only	BTG family;; Ataxin-2 C-terminal region	Protein Tob2 GN=TOB2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Tob2 [Dasypus novemcinctus]
ENSG00000183873(SCN5A)	--	0.321053045	30	0.104943852	15	0.302960607	8	0.09548835	15	0.133952943	22	0.080652827	14	0.892680195	-0.960018868	normal	0.981296309	0.490118674	normal	--	--	--	--	--	--	--	--	Cellular Component: voltage-gated sodium channel complex (GO:0001518);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated sodium channel activity (GO:0005248);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04838|0|hsa:6331|SCN5A, CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1; sodium channel, voltage-gated, type V, alpha subunit; K04838 voltage-gated sodium channel type V alpha (A)"	Adrenergic signaling in cardiomyocytes (ko04261)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Sodium ion transport-associated;; Domain of unknown function (DUF3451);; Polycystin cation channel	Sodium channel protein type 5 subunit alpha GN=SCN5A OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel protein type 5 subunit alpha isoform 2 [Odobenus rosmarus divergens]
ENSG00000183876(ARSI)	--	3.290452817	190	2.243471412	118	2.653451	151	5.787727762	336	8.779538086	439	2.585158896	151	0.012169067	0.786785813	normal	3.33E-16	1.860769072	up	0.96778566	-0.008209226	normal	0.208822713	0.989880246	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K12375|0|pps:100974291|ARSI; arylsulfatase family, member I; K12375 arylsulfatase I/J [EC:3.1.6.-] (A)"	--	[R]	General function prediction only	Sulfatase	Arylsulfatase I (Precursor) GN=ARSI OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: arylsulfatase I [Orycteropus afer afer]
ENSG00000183878(UTY)	--	3.094240215	313	3.5605987	349	2.923480681	301	1.283356524	113	1.906212599	160	2.009390715	174	1.13E-09	-1.487970357	down	5.60E-06	-1.13910111	down	0.014411942	-0.7936567	normal	5.22E-07	-1.127330871	down	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11447|0|hsa:7404|UTY, KDM6AL, UTY1; ubiquitously transcribed tetratricopeptide repeat containing, Y-linked; K11447 histone demethylase [EC:1.14.11.-] (A)"	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"JmjC domain, hydroxylase;; Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Lysine-specific demethylase 6A GN=KDM6A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lysine-specific demethylase 6A isoform X1 [Canis lupus familiaris]
ENSG00000183889(AC138969.4)	--	1.8729	44	2.620194027	64	2.107733	65	1.224834042	34	0.914679	31	1.073148479	34	0.967917188	-0.38736765	normal	0.291962393	-1.031461409	normal	0.494234408	-0.913323219	normal	0.109078805	-0.82623282	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A5 GN=NPIPA5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000183891(TTC32)	--	11.62552002	213	12.21893046	223	10.37335026	190	9.583300247	178	6.419100068	120	7.394277222	145	0.919971846	-0.287535906	normal	0.006800592	-0.906913252	normal	0.853375563	-0.394631206	normal	0.080270206	-0.521113649	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	--	--	[R]	General function prediction only	Tetratricopeptide repeat;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 32 GN=TTC32 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 32 [Ursus maritimus]
ENSG00000183914(DNAH2)	--	0.009794277	3	0.03187378	6	0.005879692	1	0	0	0.012721443	3	0.028210769	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:146754|DNAH2, DNAHC2, DNHD3; dynein, axonemal, heavy chain 2; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; Dynein heavy chain, N-terminal region 1;; P-loop containing dynein motor region D4;; ATP-binding dynein motor region D5;; P-loop containing dynein motor region D3;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; AAA ATPase domain;; ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA domain;; Type II/IV secretion system protein;; Magnesium chelatase, subunit ChlI;; Sigma-54 interaction domain"	"Dynein heavy chain 2, axonemal GN=DNAH2 OS=Homo sapiens (Human) PE=2 SV=3"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 2, axonemal [Ceratotherium simum simum]"
ENSG00000183943(PRKX)	--	14.85961162	1311	14.2774227	1283	14.00730165	1242	13.17997609	1220	11.83125735	1082	12.39281265	1082	0.975129923	-0.1344554	normal	0.93373881	-0.266904169	normal	0.95924229	-0.206985863	normal	0.283074701	-0.202534416	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04345|0|hsa:5613|PRKX, PKX1; protein kinase, X-linked (EC:2.7.11.1); K04345 protein kinase A [EC:2.7.11.11] (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Oocyte meiosis (ko04114);; Apoptosis (ko04210);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Taste transduction (ko04742);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; Insulin secretion (ko04911);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Progesterone-mediated oocyte maturation (ko04914);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Thyroid hormone synthesis (ko04918);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Vasopressin-regulated water reabsorption (ko04962);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Bile secretion (ko04976);; Parkinson's disease (ko05012);; Prion diseases (ko05020);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Vibrio cholerae infection (ko05110);; Amoebiasis (ko05146);; HTLV-I infection (ko05166);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	cAMP-dependent protein kinase catalytic subunit PRKX GN=PRKX OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cAMP-dependent protein kinase catalytic subunit PRKX [Ceratotherium simum simum]
ENSG00000183955(KMT5A)	--	15.52252259	937	15.14224231	912	15.85393753	968	20.81250515	1238	16.65536072	992	20.86547474	1262	0.797896089	0.370528086	normal	0.974455463	0.09972116	normal	0.792265056	0.373828592	normal	0.097949725	0.288750607	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11428|0|hsa:387893|SETD8, KMT5A, PR-Set7, SET07, SET8; SET domain containing (lysine methyltransferase) 8 (EC:2.1.1.43); K11428 histone-lysine N-methyltransferase SETD8 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[R]	General function prediction only	SET domain	N-lysine methyltransferase SETD8 GN=SETD8 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: N-lysine methyltransferase SETD8 isoform 1 [Odobenus rosmarus divergens]
ENSG00000183960(KCNH8)	--	0.0308808	3	0	0	0.0102699	0	0	0	0	0	0.0102259	1	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	"Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; "	"K04911|0|hsa:131096|KCNH8, ELK, ELK1, Kv12.1, elk3; potassium voltage-gated channel, subfamily H (eag-related), member 8; K04911 potassium voltage-gated channel Eag-related subfamily H member 8 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PAS domain;; Ion transport protein;; Ion channel;; Cyclic nucleotide-binding domain;; PAS fold;; PAS fold;; PAS fold	Potassium voltage-gated channel subfamily H member 8 GN=KCNH8 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily H member 8 [Equus caballus] 
ENSG00000183963(SMTN)	--	8.465971126	605	8.291898205	590	10.13815889	725	20.34597356	1393	15.19965246	1058	10.20962649	740	1.54E-09	1.170343123	up	0.000473165	0.819536396	normal	0.975826526	0.021209044	normal	0.103329932	0.710198183	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Smoothelin cytoskeleton protein;; Calponin homology (CH) domain;; CAMSAP CH domain	Smoothelin GN=SMTN OS=Homo sapiens (Human) PE=1 SV=7	Z	Cytoskeleton	PREDICTED: smoothelin isoform X4 [Leptonychotes weddellii]
ENSG00000183971(NPW)	--	3.141129728	77	2.08037544	64	2.72008	61	1.47028003	41	1.933679676	44	2.288374829	52	0.338049258	-0.914636207	normal	0.902926052	-0.546332702	normal	0.969983683	-0.232343581	normal	0.256839739	-0.580867343	normal	--	--	Molecular Function: G-protein coupled receptor binding (GO:0001664);; 	--	--	--	--	Neuropeptides B and W	Neuropeptide W-30 (Precursor) GN=NPW OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neuropeptide W [Vicugna pacos]
ENSG00000183977(PP2D1)	--	0.0267395	1	0.0267437	1	0.0799967	2	0.0793296	3	0.155614	5	0.0790858	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: catalytic activity (GO:0003824);; 	--	--	[T]	Signal transduction mechanisms	Protein phosphatase 2C	Protein phosphatase 2C-like domain-containing protein 1 GN=PP2D1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protein phosphatase 2C-like domain-containing protein 1 [Galeopterus variegatus]
ENSG00000183978(COA3)	--	66.4331	695	67.4713	719	66.2328	709	85.9174	937	73.2749	764	76.3578	807	0.718067234	0.399440887	normal	0.973681327	0.066019593	normal	0.95958095	0.178135236	normal	0.279250763	0.218706809	normal	--	--	--	"K18175|2.18911e-55|ptr:741519|CCDC56; cytochrome c oxidase assembly factor 3 homolog, mitochondrial; K18175 cytochrome c oxidase assembly factor 3, animal type (A)"	--	[S]	Function unknown	Coiled-coil domain-containing protein 56	"Cytochrome c oxidase assembly factor 3 homolog, mitochondrial GN=COA3 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: cytochrome c oxidase assembly protein 3 homolog, mitochondrial-like [Sorex araneus]"
ENSG00000184005(ST6GALNAC3)	--	5.846705505	146	2.473995279	54	3.133778297	89	1.272147487	37	1.962696	73	1.909050711	53	1.18E-09	-1.966832234	down	0.938450757	0.40375393	normal	0.57658106	-0.739639353	normal	0.326068056	-0.846230195	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: sialyltransferase activity (GO:0008373);; 	"K03373|0|ptr:450115|ST6GALNAC3, SIAT7C; ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3; K03373 N-acetylgalactosaminide alpha-2,6-sialyltransferase (sialyltransferase 7C) [EC:2.4.99.-] (A)"	Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Glycosyltransferase family 29 (sialyltransferase)	"Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 GN=ST6GALNAC3 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 [Odobenus rosmarus divergens]"
ENSG00000184007(PTP4A2)	--	121.9743326	5028	138.255595	5166	117.5420315	4782	110.5680861	4660	93.6693837	3743	131.0179134	4727	0.989876887	-0.140442364	normal	0.536332901	-0.486111186	normal	0.993053768	-0.024972764	normal	0.254118269	-0.21115003	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18041|1.04383e-122|tup:102472906|PTP4A2; protein tyrosine phosphatase type IVA, member 2; K18041 protein tyrosine phosphatase type IVA [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain"	Protein tyrosine phosphatase type IVA 2 (Precursor) GN=PTP4A2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein tyrosine phosphatase type IVA 2 isoform X1 [Bos mutus] 
ENSG00000184009(ACTG1)	--	4511.6298	103063	4551.679726	99972	4371.984084	98750	5087.076308	122423	4872.017936	112800	4591.413796	103719	0.998694972	0.217512893	normal	0.99912919	0.152742345	normal	0.999425378	0.062535172	normal	0.637294429	0.14578284	normal	[Z]	Cytoskeleton	--	"K05692|0|xla:100037088|actg1, actg1a; actin, gamma 1 a; K05692 actin beta/gamma 1 (A)"	Phagosome (ko04145);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Regulation of actin cytoskeleton (ko04810);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	Actin	"Actin, cytoplasmic 2, N-terminally processed GN=ACTG1 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: actin, cytoplasmic 2 [Bison bison bison]"
ENSG00000184014(DENND5A)	--	15.29264359	1497	14.61957135	1358	13.421115	1233	16.568237	1638	13.453951	1290	15.2749139	1432	0.981302058	0.098931786	normal	0.979125355	-0.095429918	normal	0.961840447	0.207331084	normal	0.777303073	0.070997265	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; RUN domain;; uDENN domain;; dDENN domain;; PLAT/LH2 domain	DENN domain-containing protein 5A GN=DENND5A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 5A isoform X4 [Canis lupus familiaris]
ENSG00000184047(DIABLO)	--	47.52610257	1088	40.268035	975	53.20019848	1105	53.096289	1093	54.61838017	1222	51.43984147	1099	0.980338485	-0.024183347	normal	0.903118908	0.303921761	normal	0.980634354	-0.016124298	normal	0.721622195	0.086924396	normal	--	--	Cellular Component: mitochondrion (GO:0005739);; Biological Process: apoptotic process (GO:0006915);; Biological Process: activation of cysteine-type endopeptidase activity involved in apoptotic process (GO:0006919);; 	"K10522|7.31119e-163|ptr:745126|DIABLO; diablo, IAP-binding mitochondrial protein; K10522 diablo (A)"	--	--	--	Second Mitochondria-derived Activator of Caspases	"Diablo homolog, mitochondrial (Precursor) GN=DIABLO OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: diablo homolog, mitochondrial isoform 1 [Ceratotherium simum simum]"
ENSG00000184056(VPS33B)	--	10.6753868	570	9.018126144	487	10.65106497	573	9.51414	497	9.49024	495	7.85328153	419	0.938190423	-0.22788982	normal	0.970859572	0.002073808	normal	0.553351326	-0.458455411	normal	0.321661818	-0.229627551	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Sec1 family	Vacuolar protein sorting-associated protein 33B GN=VPS33B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 33B isoform X1 [Tupaia chinensis]
ENSG00000184058(TBX1)	--	3.26996	107	3.166692	102	2.8624432	96	1.07019	35	1.55545	51	0.839665	28	2.55E-05	-1.600736366	down	0.065050025	-1.000036593	normal	1.63E-05	-1.732282963	down	0.00016552	-1.441406776	down	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K10175|0|ptr:458653|TBX1; T-box 1; K10175 T-box protein 1 (A)	--	[K]	Transcription	T-box	T-box transcription factor TBX1 GN=TBX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: T-box transcription factor TBX1 [Ochotona princeps]
ENSG00000184060(ADAP2)	--	2.364310032	124	6.282100244	102	2.332715783	143	2.003958001	105	3.53221565	127	1.084948351	69	0.945860136	-0.267180411	normal	0.937702296	0.290960295	normal	0.007167689	-1.043404712	down	0.477692011	-0.315465986	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; 	--	--	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; Pleckstrin homology domain;; PH domain;; Pleckstrin homology domain	Arf-GAP with dual PH domain-containing protein 2 GN=ADAP2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: arf-GAP with dual PH domain-containing protein 2 isoform 2 [Orcinus orca]
ENSG00000184076(UQCR10)	--	61.1114	618	63.9362	648	70.3312	727	82.5516	864	85.2588	853	74.8283	754	0.542521103	0.451638725	normal	0.788140796	0.374361763	normal	0.975327236	0.044227376	normal	0.128746887	0.288830969	normal	--	--	--	K00419|2.45016e-39|ptr:735808|UQCR10; cytochrome b-c1 complex subunit 9; K00419 ubiquinol-cytochrome c reductase subunit 9 (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like"	Cytochrome b-c1 complex subunit 9 GN=UQCR10 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: cytochrome b-c1 complex subunit 9-like [Ovis aries] 
ENSG00000184083(FAM120C)	--	5.823822335	344	4.532078674	361	7.184111	317	7.081279511	345	6.506441253	409	7.850529022	456	0.968285635	-0.026526164	normal	0.95551128	0.158053108	normal	0.396681443	0.514203405	normal	0.401754222	0.22308147	normal	--	--	--	--	--	--	--	--	Constitutive coactivator of PPAR-gamma-like protein 2 GN=FAM120C OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: constitutive coactivator of PPAR-gamma-like protein 2 isoform X1 [Pteropus alecto] 
ENSG00000184110(EIF3C)	--	4.185615567	234	4.612132607	225	4.843331716	243	3.6872234	212	3.583864095	214	2.9397422	182	0.953482709	-0.172088748	normal	0.962324667	-0.093099043	normal	0.783975041	-0.422261937	normal	0.503126917	-0.228883561	normal	--	--	Molecular Function: translation initiation factor activity (GO:0003743);; Molecular Function: protein binding (GO:0005515);; Cellular Component: eukaryotic translation initiation factor 3 complex (GO:0005852);; Biological Process: translational initiation (GO:0006413);; Molecular Function: translation initiation factor binding (GO:0031369);; 	"K03252|0|hsa:8663|EIF3C, EIF3CL, EIF3S8, eIF3-p110; eukaryotic translation initiation factor 3, subunit C; K03252 translation initiation factor 3 subunit C (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Eukaryotic translation initiation factor 3 subunit 8 N-terminus;; PCI domain	Eukaryotic translation initiation factor 3 subunit C {ECO:0000255|HAMAP-Rule:MF_03002} OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit C-like isoform 1 [Odobenus rosmarus divergens] 
ENSG00000184113(CLDN5)	--	0.209755562	6	0.107489511	4	0.07913048	2	0.0280121	1	0.079298	2	0.08459024	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06087|2.41791e-155|hsa:7122|CLDN5, AWAL, BEC1, CPETRL1, TMVCF; claudin 5; K06087 claudin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-5 GN=CLDN5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: claudin 5 [Odobenus rosmarus divergens]
ENSG00000184144(CNTN2)	--	0.027624379	2	0	0	0.011725209	1	0	0	0.016181814	0	0.00639952	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06760|0|hsa:6900|CNTN2, AXT, FAME5, TAG-1, TAX, TAX1; contactin 2 (axonal); K06760 contactin 2 (A)"	Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin C2-set domain	Contactin-2 (Precursor) GN=CNTN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: contactin-2 [Galeopterus variegatus]
ENSG00000184154(LRTOMT)	--	7.4134923	135	7.219906	163	6.9432608	142	4.0302987	115	6.9877751	118	6.1247684	152	0.944973536	-0.25896037	normal	0.767977757	-0.482228899	normal	0.965438673	0.088972955	normal	0.628904125	-0.213134525	normal	[R]	General function prediction only	Molecular Function: O-methyltransferase activity (GO:0008171);; 	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	O-methyltransferase;; Methyltransferase domain	Transmembrane O-methyltransferase {ECO:0000250|UniProtKB:A1Y9I9} GN=PP7517 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: LOW QUALITY PROTEIN: transmembrane O-methyltransferase-like [Tursiops truncatus]
ENSG00000184156(KCNQ3)	--	0.517039914	83	0.563185043	86	0.87413381	135	1.281982044	182	1.010121165	141	0.848208999	156	0.000979421	1.087997891	up	0.405139585	0.682401059	normal	0.953737304	0.198227849	normal	0.055792567	0.635070726	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: potassium channel activity (GO:0005267);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04928|0|nle:100593616|KCNQ3; potassium voltage-gated channel, KQT-like subfamily, member 3; K04928 potassium voltage-gated channel KQT-like subfamily member 3 (A)"	Cholinergic synapse (ko04725)	[P]	Inorganic ion transport and metabolism	KCNQ voltage-gated potassium channel;; Ankyrin-G binding motif of KCNQ2-3;; Ion transport protein;; Ion channel	Potassium voltage-gated channel subfamily KQT member 3 GN=KCNQ3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	"PREDICTED: potassium voltage-gated channel subfamily KQT member 3, partial [Tupaia chinensis]"
ENSG00000184160(ADRA2C)	--	8.14146	205	5.654092	159	6.545218	193	8.325628	218	6.37058	172	6.725998	177	0.965710506	0.057454373	normal	0.963277848	0.091121839	normal	0.960403207	-0.132062001	normal	1	0.003914701	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04140|0|nle:100591173|ADRA2C; adrenoceptor alpha 2C; K04140 adrenergic receptor alpha-2C (A)	cGMP-PKG signaling pathway (ko04022);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Alpha-2C adrenergic receptor GN=ADRA2C OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	alpha-2C adrenoceptor [Tupaia belangeri]
ENSG00000184162(NR2C2AP)	--	12.197056	214	12.938888	240	11.575447	224	11.433396	218	12.793889	248	10.602174	215	0.966967582	-0.004085861	normal	0.965766318	0.025719729	normal	0.965243404	-0.066991825	normal	0.983948554	-0.014834263	normal	--	--	--	--	--	--	--	F5/8 type C domain	Nuclear receptor 2C2-associated protein GN=NR2C2AP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor 2C2-associated protein [Ceratotherium simum simum]
ENSG00000184163(C1QTNF12)	--	0.0745639	1	0	0	0	0	0.0730311	1	0	0	0.146891	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain	Adipolin gCTRP12 (Precursor) GN=FAM132A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM132A [Tupaia chinensis] 
ENSG00000184164(CRELD2)	--	19.32462869	494	18.026432	478	19.45408199	523	26.43863229	695	21.01002307	540	19.49625815	499	0.524905389	0.460457185	normal	0.958831215	0.154063437	normal	0.969443603	-0.075838046	normal	0.44738228	0.191827845	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[S]	Function unknown	TLR4 regulator and MIR-interacting MSAP;; Calcium-binding EGF domain	Cysteine-rich with EGF-like domain protein 2 (Precursor) GN=CRELD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: cysteine-rich with EGF-like domain protein 2 [Galeopterus variegatus]
ENSG00000184178(SCFD2)	--	4.0917324	226	4.611575153	233	6.650116446	280	6.312099145	332	6.918123265	336	5.733712489	240	0.461358898	0.521089546	normal	0.521178959	0.503967035	normal	0.937753032	-0.229344514	normal	0.332467214	0.275447526	normal	--	--	Biological Process: vesicle docking involved in exocytosis (GO:0006904);; Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	--	--	Sec1 family	Sec1 family domain-containing protein 2 GN=SCFD2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sec1 family domain-containing protein 2 isoform X1 [Equus caballus]
ENSG00000184182(UBE2F)	--	21.96628567	604	18.45360847	499	19.99792828	524	16.35109154	431	14.950589	420	14.6840308	381	0.329682218	-0.516130451	normal	0.915367488	-0.269186551	normal	0.537821509	-0.466481526	normal	0.034331152	-0.42280177	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10687|6.7561e-136|ptr:460054|UBE2F; ubiquitin-conjugating enzyme E2F (putative); K10687 ubiquitin-conjugating enzyme E2 F [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	NEDD8-conjugating enzyme UBE2F GN=UBE2F OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NEDD8-conjugating enzyme UBE2F-like isoform 1 [Dasypus novemcinctus]
ENSG00000184185(KCNJ12)	--	0.405381216	30	0.306332421	30	0.155491218	16	0.152356281	15	0.215412557	13	0.231100134	17	0.892680195	-0.960018868	normal	0.790632756	-1.138435788	normal	--	--	--	--	--	--	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05005|0|hsa:3768|KCNJ12, IRK-2, IRK2, KCNJN1, Kir2.2, Kir2.2v, hIRK, hIRK1, hkir2.2x, kcnj12x; potassium inwardly-rectifying channel, subfamily J, member 12; K05005 potassium inwardly-rectifying channel subfamily J member 12 (A)"	Cholinergic synapse (ko04725);; Oxytocin signaling pathway (ko04921)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel;; Inward rectifier potassium channel N-terminal	ATP-sensitive inward rectifier potassium channel 12 GN=KCNJ12 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: ATP-sensitive inward rectifier potassium channel 12 isoform X2 [Galeopterus variegatus]
ENSG00000184194(GPR173)	--	0	0	0	0	0	0	0.023332828	2	0.056750235	4	0.011534887	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04300|0|ssc:100625145|GPR173; G protein-coupled receptor 173; K04300 super conserved receptor expressed in brain 3 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 173 GN=GPR173 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 173 [Ailuropoda melanoleuca] 
ENSG00000184203(PPP1R2)	--	8.593133489	436	7.764936705	346	8.72874083	437	7.090294085	365	8.450644896	429	7.963307224	405	0.903877757	-0.286160026	normal	0.903249365	0.287648118	normal	0.963521134	-0.11758003	normal	0.90328187	-0.044441374	normal	--	--	Molecular Function: protein phosphatase inhibitor activity (GO:0004864);; Biological Process: regulation of signal transduction (GO:0009966);; Biological Process: regulation of phosphoprotein phosphatase activity (GO:0043666);; 	"K16833|5.16614e-127|ptr:460949|PPP1R2; protein phosphatase 1, regulatory (inhibitor) subunit 2; K16833 protein phosphatase inhibitor 2 (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Protein phosphatase inhibitor 2 (IPP-2)	Protein phosphatase inhibitor 2 GN=PPP1R2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	protein phosphatase inhibitor 2 [Canis lupus familiaris] 
ENSG00000184205(TSPYL2)	--	6.205939576	384	5.413472212	340	5.315277169	337	3.354942	210	3.967024	246	3.394132613	219	0.000758477	-0.896619757	normal	0.56947932	-0.485750997	normal	0.153017586	-0.626593641	normal	0.002120078	-0.67355832	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11285|0|ptr:744228|TSPYL2; TSPY-like 2; K11285 TSPY-like 2 (A)	--	[L]	"Replication, recombination and repair"	Nucleosome assembly protein (NAP)	Testis-specific Y-encoded-like protein 2 GN=TSPYL2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: testis-specific Y-encoded-like protein 2 [Galeopterus variegatus]
ENSG00000184206(GOLGA6L4)	--	3.356248646	278	4.133627	290	4.137975	268	3.864603787	302	4.2683394	318	4.159679998	328	0.964214217	0.088163846	normal	0.961236262	0.110994443	normal	0.911502475	0.281732061	normal	0.617225696	0.160343868	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Putative golgin subfamily A member 6-like protein 3 GN=GOLGA6L3 OS=Homo sapiens (Human) PE=5 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000184208(C22orf46)	--	2.60842	434	2.6885	463	2.600437	427	2.88093	470	2.715565	433	3.1199	511	0.967488763	0.083848176	normal	0.963204939	-0.117674178	normal	0.926932568	0.249985441	normal	0.822074488	0.073798519	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C22orf46 (Precursor) GN=C22orf46 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C22orf46 homolog [Ceratotherium simum simum]
ENSG00000184209(SNRNP35)	--	11.18597653	215	9.572614	216	11.60444692	209	11.51448811	240	11.9191219	223	10.48386074	194	0.960137448	0.127006187	normal	0.965617366	0.024417591	normal	0.961799501	-0.114874757	normal	0.980805297	0.015953085	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13155|1.0878e-131|ptr:452345|SNRNP35; small nuclear ribonucleoprotein 35kDa (U11/U12); K13155 U11/U12 small nuclear ribonucleoprotein 35 kDa protein (A)	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	U11/U12 small nuclear ribonucleoprotein 35 kDa protein GN=SNRNP35 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: U11/U12 small nuclear ribonucleoprotein 35 kDa protein isoform X1 [Ursus maritimus] 
ENSG00000184216(IRAK1)	--	73.089401	5166	79.17002465	5612	85.2699406	5938	102.5834404	7218	97.42947	6830	92.86995981	6497	0.714176766	0.451605146	normal	0.977259111	0.261879957	normal	0.992459568	0.121475585	normal	0.119070018	0.27620891	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; 	K04730|0|pon:100437883|IRAK1; interleukin-1 receptor-associated kinase 1; K04730 interleukin-1 receptor-associated kinase 1 [EC:2.7.11.1] (A)	NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Toll-like receptor signaling pathway (ko04620);; Neurotrophin signaling pathway (ko04722);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Measles (ko05162);; Epstein-Barr virus infection (ko05169)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Death domain	Interleukin-1 receptor-associated kinase 1 GN=IRAK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: interleukin-1 receptor-associated kinase 1, partial [Ceratotherium simum simum]"
ENSG00000184220(CMSS1)	--	31.93219736	493	28.18975024	497	33.05872	575	30.9103542	554	28.97907029	493	20.17993739	382	0.96270154	0.137062971	normal	0.97046641	-0.032983992	normal	0.11736964	-0.596342774	normal	0.580062213	-0.153146054	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[R]	General function prediction only	U3-containing 90S pre-ribosomal complex subunit;; DEAD/DEAH box helicase	Protein CMSS1 GN=CMSS1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: protein CMSS1 isoform X1 [Felis catus]
ENSG00000184221(OLIG1)	--	0	0	0	0	0	0	0.072956141	1	0.0313714	0	0.0320974	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09085|2.8408e-101|hsa:116448|OLIG1, BHLHB6, BHLHE21; oligodendrocyte transcription factor 1; K09085 class B basic helix-loop-helix protein 1/6/7 (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Oligodendrocyte transcription factor 1 GN=OLIG1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: oligodendrocyte transcription factor 1 [Camelus dromedarius]
ENSG00000184226(PCDH9)	--	4.050381	842	6.159795913	1407	4.106182381	880	6.400498	1283	7.485048	1604	5.75003	1160	0.101010746	0.575939751	normal	0.972683521	0.167456592	normal	0.749926931	0.389672899	normal	0.423320215	0.349296017	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K16498|0|ggo:101151514|PCDH9; protocadherin-9 isoform 1; K16498 protocadherin delta 1 (A)	--	--	--	Cadherin domain;; Protocadherin;; Cadherin-like	Protocadherin-9 (Precursor) GN=PCDH9 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protocadherin-9 isoform 1 [Equus caballus]
ENSG00000184227(ACOT1)	--	3.986463	101	3.09465	83	2.8314303	76	3.45331	91	4.976671	127	6.863754	178	0.963843822	-0.178388461	normal	0.68400645	0.583564493	normal	0.00014913	1.203410022	up	0.264835604	0.587501695	normal	[R]	General function prediction only	--	"K01068|0|hsa:641371|ACOT1, ACH2, CTE-1, LACH2; acyl-CoA thioesterase 1 (EC:3.1.2.2); K01068 acyl-coenzyme A thioesterase 1/2/4 [EC:3.1.2.2] (A)"	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040)	--	--	BAAT / Acyl-CoA thioester hydrolase C terminal;; Acyl-CoA thioester hydrolase/BAAT N-terminal region;; Dienelactone hydrolase family	Acyl-coenzyme A thioesterase 1 GN=ACOT1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	"PREDICTED: acyl-coenzyme A thioesterase 2, mitochondrial-like isoform 2 [Ceratotherium simum simum]"
ENSG00000184232(OAF)	--	6.145286941	279	4.163477424	192	6.351604948	233	6.616020041	267	7.379256306	304	7.335562722	292	0.963574408	-0.093729929	normal	0.169225351	0.637515418	normal	0.89175621	0.315514036	normal	0.352020539	0.27296721	normal	--	--	--	--	--	--	--	"Transcriptional regulator, Out at first"	Out at first protein homolog (Precursor) GN=OAF OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"PREDICTED: out at first protein homolog, partial [Vicugna pacos]"
ENSG00000184254(ALDH1A3)	--	22.955514	1537	19.551806	1299	18.9016685	1268	8.9710427	588	7.019369287	480	3.657609145	253	2.38E-14	-1.41468235	down	2.59E-14	-1.45481596	down	0	-2.32672901	down	4.89E-13	-1.659003661	down	[C]	Energy production and conversion	Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00129|0|hsa:220|ALDH1A3, ALDH1A6, ALDH6, MCOP8, RALDH3; aldehyde dehydrogenase 1 family, member A3 (EC:1.2.1.5); K00129 aldehyde dehydrogenase (NAD(P)+) [EC:1.2.1.5] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Histidine metabolism (ko00340);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; beta-Alanine metabolism (ko00410);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[C]	Energy production and conversion	Aldehyde dehydrogenase family	Aldehyde dehydrogenase family 1 member A3 GN=ALDH1A3 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: aldehyde dehydrogenase family 1 member A3 [Condylura cristata]
ENSG00000184258(CDR1)	--	1.01508	58	0.494003	29	0.569901	32	0.31066	18	0.44964	25	0.337159	19	0.005211398	-1.636825882	down	0.982738491	-0.223013699	normal	0.945474682	-0.716000483	normal	0.143402945	-0.961867016	normal	--	--	--	--	--	--	--	--	Cerebellar degeneration-related antigen 1 GN=CDR1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: cerebellar degeneration-related antigen 1, partial [Bison bison bison]"
ENSG00000184260(HIST2H2AC)	--	1.42476	3	2.22511	5	3.79629	8	1.22649	3	2.25526	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.58007e-70|bacu:103019385|histone H2A.J-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 2-C GN=HIST2H2AC OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-C-like isoform X2 [Sus scrofa]
ENSG00000184261(KCNK12)	--	0.056723364	6	0.093184446	10	0.102242707	10	0.047233547	5	0.009273335	0	0.009463554	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	"K04921|0|ptr:459216|KCNK12; potassium channel, subfamily K, member 12; K04921 potassium channel subfamily K member 12 (A)"	--	[P]	Inorganic ion transport and metabolism	Ion channel	Potassium channel subfamily K member 12 GN=KCNK12 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	"PREDICTED: potassium channel subfamily K member 12, partial [Lipotes vexillifer]"
ENSG00000184270(HIST2H2AB)	--	0	0	0	0	0	0	1.17296	3	0.865307	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.21021e-70|umr:103667569|histone H2A type 2-B; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 2-B GN=HIST2H2AB OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-B-like [Balaenoptera acutorostrata scammoni]
ENSG00000184271(POU6F1)	--	0.667509914	55	0.498096484	48	0.470110418	39	0.56834848	50	0.825179675	66	0.732508026	78	0.975512967	-0.163541801	normal	0.939987846	0.42650413	normal	0.250798537	0.964760428	normal	0.452326625	0.429877436	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09368|0|nle:100584290|POU6F1; POU class 6 homeobox 1; K09368 POU domain transcription factor, class 6 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 6, transcription factor 1 GN=POU6F1 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: POU domain, class 6, transcription factor 1 [Oryctolagus cuniculus]"
ENSG00000184277(TM2D3)	--	34.07854888	593	29.11561396	512	32.29863109	561	28.73693555	513	28.40573071	497	31.78854807	553	0.93338965	-0.23923836	normal	0.969291704	-0.064132242	normal	0.972593751	-0.028934171	normal	0.682375709	-0.112996999	normal	--	--	--	--	--	[R]	General function prediction only	TM2 domain	TM2 domain-containing protein 3 (Precursor) GN=TM2D3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: TM2 domain-containing protein 3 isoformX2 [Canis lupus familiaris]
ENSG00000184281(TSSC4)	--	18.77597805	545	21.1312886	633	20.99330208	592	23.19117634	675	22.75313324	664	24.266632	699	0.911569481	0.277096018	normal	0.972974224	0.04744052	normal	0.939547923	0.230860529	normal	0.425156593	0.182289012	normal	--	--	--	--	--	--	--	Tumour suppressing sub-chromosomal transferable candidate 4	Protein TSSC4 GN=TSSC4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein TSSC4 [Ceratotherium simum simum]
ENSG00000184292(TACSTD2)	--	0.0261745	1	0	0	0.0247604	0	0	0	0.0251978	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K17288|0|ptr:456890|TACSTD2; tumor-associated calcium signal transducer 2; K17288 tumor-associated calcium signal transducer 2 (A)	--	--	--	Thyroglobulin type-1 repeat	Tumor-associated calcium signal transducer 2 (Precursor) GN=TACSTD2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tumor-associated calcium signal transducer 2 [Sus scrofa]
ENSG00000184304(PRKD1)	--	3.377477751	235	3.474197069	225	3.094809903	165	2.265936468	158	3.113521681	212	2.792357985	179	0.343164556	-0.598760017	normal	0.96116879	-0.106549367	normal	0.963105931	0.108249343	normal	0.575135028	-0.208313926	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; Biological Process: intracellular signal transduction (GO:0035556);; "	K06070|0|mcf:102140172|PRKD1; protein kinase D1; K06070 protein kinase D [EC:2.7.11.13] (A)	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Phorbol esters/diacylglycerol binding domain (C1 domain);; PH domain;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase D1 GN=PRKD1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase D1 isoform X2 [Bos taurus]
ENSG00000184305(CCSER1)	--	0.00997583	1	0.086989561	4	0.021664992	0	0.173266202	8	0.5274831	27	0.306976865	15	--	--	--	0.033795785	2.352943859	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Serine-rich coiled-coil domain-containing protein 1 GN=CCSER1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: serine-rich coiled-coil domain-containing protein 1 isoform X1 [Canis lupus familiaris]
ENSG00000184307(ZDHHC23)	--	3.887345554	335	4.764553396	338	3.879116	347	1.593395072	132	1.657252604	151	1.422301068	106	1.63E-08	-1.364113503	down	2.81E-06	-1.175810906	down	6.92E-13	-1.704923098	down	1.55E-10	-1.412348178	down	[R]	General function prediction only	--	--	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC23 GN=ZDHHC23 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC23 [Condylura cristata]
ENSG00000184313(MROH7)	--	0.032138351	2	0.013704014	1	0	0	0	0	0.013439878	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	Maestro heat-like repeat-containing protein family member 7 GN=MROH7 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: HEAT repeat-containing protein 8 [Odobenus rosmarus divergens]
ENSG00000184343(SRPK3)	--	2.289549651	280	2.527999741	318	1.878087389	237	2.016323699	194	1.684922685	209	1.587076224	212	0.398007585	-0.556511089	normal	0.182234866	-0.623265854	normal	0.95423911	-0.167980285	normal	0.076583264	-0.462518763	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08832|0|hsa:26576|SRPK3, MSSK-1, MSSK1, STK23; SRSF protein kinase 3 (EC:2.7.11.1); K08832 serine/threonine-protein kinase SRPK3 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	SRSF protein kinase 3 GN=SRPK3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SRSF protein kinase 3 [Oryctolagus cuniculus]
ENSG00000184347(SLIT3)	--	12.23537754	1793	12.32058488	1797	11.46584694	1662	11.14105955	1661	11.54162893	1704	7.514664954	1160	0.978696351	-0.141030072	normal	0.982336706	-0.098006917	normal	0.230224894	-0.526510382	normal	0.319093617	-0.237188479	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K06850|0|hsa:6586|SLIT3, MEGF5, SLIL2, SLIT1, Slit-3, slit2; slit homolog 3 (Drosophila); K06850 slit 3 (A)"	Axon guidance (ko04360)	[WT]	Extracellular structures;; Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; EGF-like domain;; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Laminin G domain;; Leucine rich repeat N-terminal domain;; Laminin G domain;; Leucine-rich repeat;; Human growth factor-like EGF;; Leucine rich repeat C-terminal domain;; Leucine Rich repeat	Slit homolog 3 protein (Precursor) GN=SLIT3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: slit homolog 3 protein isoform X1 [Condylura cristata]
ENSG00000184349(EFNA5)	--	37.60816	1602	42.61412809	1792	36.172707	1549	28.04303641	1290	22.729286	1169	29.66275136	1392	0.86233108	-0.342967935	normal	0.03053883	-0.637051232	normal	0.973475737	-0.162302135	normal	0.014388426	-0.3813472	normal	--	--	Cellular Component: membrane (GO:0016020);; 	K05462|1.60868e-159|pps:100976740|EFNA5; ephrin-A5; K05462 ephrin-A (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Ephrin	Ephrin-A5 (Precursor) GN=EFNA5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ephrin-A5 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000184357(HIST1H1B)	--	0	0	0	0	0	0	0.230414	2	0	0	0.233223	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11275|1.55982e-29|nle:100596211|histone H1.5-like; K11275 histone H1/5 (A)	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	Histone H1.5 GN=HIST1H1B OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5 [Galeopterus variegatus]
ENSG00000184361(SPATA32)	--	0.595244	16	0.600688	16	0.502649	13	0.184079	5	0.180414	4	0.144978	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: spermatogenesis (GO:0007283);; 	--	--	--	--	Vitamin A-deficiency (VAD) rat model signalling	Spermatogenesis-associated protein 32 GN=SPATA32 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: spermatogenesis-associated protein 32 [Tupaia chinensis]
ENSG00000184363(PKP3)	--	14.46374807	691	14.28510669	717	16.664206	767	18.38538082	913	17.7490986	836	17.49772543	865	0.790387312	0.370378488	normal	0.953687475	0.199712863	normal	0.963666226	0.164875832	normal	0.20998355	0.244008553	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat	Plakophilin-3 GN=PKP3 OS=Homo sapiens (Human) PE=1 SV=1	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: plakophilin-3 [Ceratotherium simum simum]
ENSG00000184368(MAP7D2)	--	7.238016	647	6.799844	612	7.633133666	682	6.6585821	596	7.453247547	663	6.330222	563	0.962755953	-0.148917038	normal	0.969756587	0.093827868	normal	0.90668544	-0.284233453	normal	0.668113395	-0.112402751	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: microtubule cytoskeleton (GO:0015630);; 	--	--	--	--	MAP7 (E-MAP-115) family	MAP7 domain-containing protein 2 GN=MAP7D2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: MAP7 domain-containing protein 2 [Odobenus rosmarus divergens]
ENSG00000184371(CSF1)	--	20.84921205	1440	24.52898014	1920	20.89127047	1488	16.66161035	1165	18.36469055	1259	31.80469014	2052	0.867822183	-0.336171451	normal	0.035847355	-0.629637293	normal	0.546366529	0.454969375	normal	0.826877892	-0.134940238	normal	--	--	Molecular Function: cytokine activity (GO:0005125);; Molecular Function: growth factor activity (GO:0008083);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05453|0|hsa:1435|CSF1, CSF-1, MCSF; colony stimulating factor 1 (macrophage) (EC:2.7.10.1); K05453 macrophage colony-stimulating factor 1 (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Osteoclast differentiation (ko04380);; Hematopoietic cell lineage (ko04640);; TNF signaling pathway (ko04668);; Rheumatoid arthritis (ko05323)	--	--	Macrophage colony stimulating factor-1 (CSF-1)	Processed macrophage colony-stimulating factor 1 (Precursor) GN=CSF1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: macrophage colony-stimulating factor 1 isoform 2 [Orcinus orca]
ENSG00000184378(ACTRT3)	--	1.647448	67	2.18297433	83	1.107992	43	2.313217528	87	2.526178	91	2.318689	88	0.945964532	0.339180789	normal	0.968498355	0.109424152	normal	0.126597533	0.999801529	normal	0.360462383	0.440752874	normal	--	--	--	--	--	[Z]	Cytoskeleton	Actin	Actin-related protein T3 GN=ACTRT3 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: actin-related protein T3 [Ceratotherium simum simum]
ENSG00000184381(PLA2G6)	--	2.239601633	132	2.786839929	101	1.864032095	95	1.518988979	62	1.65777541	64	2.804584106	154	0.004795123	-1.101858988	down	0.631298206	-0.666980623	normal	0.352466548	0.680057869	normal	0.792609278	-0.24697136	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: lipid metabolic process (GO:0006629);; 	K16343|0|ggo:101154603|PLA2G6; 85/88 kDa calcium-independent phospholipase A2; K16343 calcium-independent phospholipase A2 [EC:3.1.1.4] (A)	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; Inflammatory mediator regulation of TRP channels (ko04750)	[I]	Lipid transport and metabolism	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Patatin-like phospholipase	85/88 kDa calcium-independent phospholipase A2 GN=PLA2G6 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: 85/88 kDa calcium-independent phospholipase A2 isoform X1 [Vicugna pacos]
ENSG00000184384(MAML2)	--	1.381124096	200	1.489851839	199	1.93520146	276	2.8883606	415	3.026579285	429	2.458045251	358	3.80E-05	1.016743977	up	8.20E-06	1.081055632	up	0.828559996	0.365238016	normal	9.64E-05	0.811520503	normal	--	--	Molecular Function: transcription coactivator activity (GO:0003713);; Biological Process: Notch signaling pathway (GO:0007219);; Cellular Component: nuclear speck (GO:0016607);; Biological Process: positive regulation of transcription from RNA polymerase II promoter (GO:0045944);; 	"K06061|0|hsa:84441|MAML2, MAM-3, MAM2, MAM3, MLL-MAML2; mastermind-like 2 (Drosophila); K06061 mastermind (A)"	Notch signaling pathway (ko04330)	--	--	MamL-1 domain	Mastermind-like protein 2 GN=MAML2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mastermind-like protein 2 [Galeopterus variegatus]
ENSG00000184389(A3GALT2)	--	0.0817857	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: carbohydrate metabolic process (GO:0005975);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	--	--	--	--	Glycosyltransferase family 6	Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form GN=ABO OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: alpha 1,3-galactosyltransferase 2 [Loxodonta africana]"
ENSG00000184402(SS18L1)	--	5.650721503	395	5.059042249	388	6.450145985	469	5.058883474	371	4.4471972	354	4.803246639	373	0.962256197	-0.120780842	normal	0.956207523	-0.153108807	normal	0.85299215	-0.337480722	normal	0.424636867	-0.210212962	normal	--	--	Molecular Function: transcription coactivator activity (GO:0003713);; 	--	--	[K]	Transcription	SSXT protein (N-terminal region)	Calcium-responsive transactivator GN=SS18L1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: calcium-responsive transactivator [Sarcophilus harrisii]
ENSG00000184408(KCND2)	--	0.0111005	1	0.063598262	3	0.021181573	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: protein homooligomerization (GO:0051260);; Biological Process: transmembrane transport (GO:0055085);; 	"K04892|0|nle:100603164|KCND2; potassium voltage-gated channel, Shal-related subfamily, member 2; K04892 potassium voltage-gated channel Shal-related subfamily D member 2 (A)"	Serotonergic synapse (ko04726)	[P]	Inorganic ion transport and metabolism	Domain of unknown function (DUF3399);; Ion transport protein;; BTB/POZ domain;; Shal-type voltage-gated potassium channels;; Ion channel	Potassium voltage-gated channel subfamily D member 2 GN=KCND2 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily D member 2 [Sorex araneus]
ENSG00000184428(TOP1MT)	--	16.06700242	720	14.61280001	685	14.55934948	692	11.02172232	477	13.56044264	588	11.89545658	551	0.057148032	-0.62319337	normal	0.934344303	-0.241139133	normal	0.849999453	-0.336185949	normal	0.031756354	-0.396612559	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase type I activity (GO:0003917);; Cellular Component: chromosome (GO:0005694);; Biological Process: DNA topological change (GO:0006265);; 	"K03163|0|ptr:472883|TOP1MT, TOP1; topoisomerase (DNA) I, mitochondrial (EC:5.99.1.2); K03163 DNA topoisomerase I [EC:5.99.1.2] (A)"	--	[L]	"Replication, recombination and repair"	"Eukaryotic DNA topoisomerase I, DNA binding fragment;; Eukaryotic DNA topoisomerase I, catalytic core;; C-terminal topoisomerase domain"	"DNA topoisomerase I, mitochondrial (Precursor) GN=TOP1MT OS=Homo sapiens (Human) PE=1 SV=1"	L	"Replication, recombination and repair"	"PREDICTED: DNA topoisomerase I, mitochondrial isoform X1 [Equus caballus]"
ENSG00000184432(COPB2)	--	41.86059708	2558	40.014629	2573	41.786814	2611	47.198073	3074	53.60762703	3339	45.8213527	2929	0.969366919	0.234140211	normal	0.890732582	0.354354795	normal	0.982945667	0.157428161	normal	0.145685588	0.249782563	normal	[R]	General function prediction only	Molecular Function: structural molecule activity (GO:0005198);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; 	"K17302|0|hsa:9276|COPB2, beta'-COP; coatomer protein complex, subunit beta 2 (beta prime); K17302 coatomer, subunit beta' (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Coatomer WD associated region;; WD domain, G-beta repeat"	Coatomer subunit beta' GN=COPB2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: coatomer subunit beta' [Canis lupus familiaris]
ENSG00000184434(LRRC19)	--	0.101995	5	0.0617931	3	0.123774	5	0.0602221	3	0.0587659	2	0.120514	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine-rich repeat family 19 TM domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies)	Leucine-rich repeat-containing protein 19 (Precursor) GN=LRRC19 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 19 [Physeter catodon]
ENSG00000184436(THAP7)	--	15.87957	318	15.15706	304	14.88869	318	14.81068	316	13.48632	279	14.04477	295	0.967406228	-0.039741848	normal	0.956635661	-0.144482209	normal	0.961760416	-0.116030198	normal	0.782273299	-0.100251401	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	THAP domain	THAP domain-containing protein 7 GN=THAP7 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: THAP domain-containing protein 7 [Galeopterus variegatus] 
ENSG00000184445(KNTC1)	--	15.12504353	1818	13.29161641	1798	13.05770618	1792	12.30744085	1703	9.78747204	1440	13.62418931	1606	0.980616264	-0.124996851	normal	0.875039868	-0.341429134	normal	0.975077164	-0.16624191	normal	0.247815697	-0.208924212	normal	--	--	--	"K11577|0|hsa:9735|KNTC1, ROD; kinetochore associated 1; K11577 kinetochore-associated protein 1 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Rough deal protein C-terminal region	Kinetochore-associated protein 1 GN=KNTC1 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: kinetochore-associated protein 1 [Galeopterus variegatus]
ENSG00000184451(CCR10)	--	2.295534171	50	2.089334442	44	2.040658557	44	1.046676967	25	1.373197202	28	1.398585357	29	0.59847749	-0.987097298	normal	0.920474579	-0.64546198	normal	0.939706542	-0.584813961	normal	0.177391494	-0.771781072	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04185|1.72254e-133|ggo:101125806|CCR10; c-C chemokine receptor type 10; K04185 C-C chemokine receptor type 10 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Intestinal immune network for IgA production (ko04672)	--	--	7 transmembrane receptor (rhodopsin family)	C-C chemokine receptor type 10 GN=CCR10 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: C-C chemokine receptor type 10 [Oryctolagus cuniculus]
ENSG00000184454(NCMAP)	--	1.281784	88	0.538467995	38	0.577597064	40	0.151366831	10	0.290286394	20	0.155006476	11	1.70E-11	-2.984788569	down	0.842902353	-0.897403895	normal	0.04128583	-1.737832202	normal	0.034602319	-2.038656683	normal	--	--	--	--	--	--	--	--	Noncompact myelin-associated protein GN=NCMAP OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: noncompact myelin-associated protein [Orcinus orca]
ENSG00000184465(WDR27)	--	5.236985118	598	5.695993739	614	4.835929428	632	3.902857125	484	3.968666144	431	5.463784982	658	0.851215254	-0.33501182	normal	0.296097791	-0.530409313	normal	0.973499779	0.049754897	normal	0.362483001	-0.249553497	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat;; Putative binding domain"	WD repeat-containing protein 27 GN=WDR27 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: WD repeat-containing protein 27 [Equus caballus]
ENSG00000184470(TXNRD2)	--	14.49812589	439	15.45612715	429	14.16255542	438	15.09596917	446	11.94342965	378	21.70797811	609	0.970536983	-0.007981779	normal	0.944585296	-0.203254053	normal	0.520091378	0.465849923	normal	0.800365326	0.113607041	normal	[C]	Energy production and conversion	Biological Process: tRNA processing (GO:0008033);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00384|0|pps:100982284|TXNRD2; thioredoxin reductase 2; K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9] (A)	Pyrimidine metabolism (ko00240);; Selenocompound metabolism (ko00450)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase;; Glucose inhibited division protein A"	"Thioredoxin reductase 2, mitochondrial (Precursor) GN=TXNRD2 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"Thioredoxin reductase 2, mitochondrial [Pteropus alecto]"
ENSG00000184471(C1QTNF8)	--	0	0	0	0	0.035352	0	0	0	0.073384614	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain	Complement C1q tumor necrosis factor-related protein 8 (Precursor) GN=C1QTNF8 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: complement C1q tumor necrosis factor-related protein 8 [Vicugna pacos]
ENSG00000184481(FOXO4)	--	2.138032852	143	1.197570986	82	1.728436783	117	1.61168826	108	1.7293893	115	2.136348563	144	0.856480291	-0.430474402	normal	0.865672458	0.45932821	normal	0.935303699	0.28790888	normal	0.895327936	0.0816363	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K12358|0|pps:100995079|FOXO4; forkhead box O4; K12358 forkhead box protein O4 (A)	Ras signaling pathway (ko04014);; FoxO signaling pathway (ko04068)	[K]	Transcription	Fork head domain	Forkhead box protein O4 GN=FOXO4 OS=Homo sapiens (Human) PE=1 SV=5	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: forkhead box protein O4 [Equus caballus] 
ENSG00000184486(POU3F2)	--	0	0	0.0121548	1	0	0	0.0122826	1	0.0358281	2	0.0487889	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09365|0|ptr:472255|POU3F2, brn-2; POU class 3 homeobox 2; K09365 POU domain transcription factor, class 3 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 3, transcription factor 2 GN=POU3F2 OS=Homo sapiens (Human) PE=1 SV=4"	K	Transcription	"PREDICTED: POU domain, class 3, transcription factor 2 [Odobenus rosmarus divergens]"
ENSG00000184489(PTP4A3)	--	9.326264403	259	5.484549406	159	3.297775095	103	2.55517629	71	3.926149158	123	3.845480337	101	4.77E-13	-1.875121603	down	0.876480449	-0.387591121	normal	0.970357266	-0.036046018	normal	0.277665806	-0.841605089	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K18041|6.63347e-127|mcf:102122080|PTP4A3; protein tyrosine phosphatase type IVA, member 3; K18041 protein tyrosine phosphatase type IVA [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain"	Protein tyrosine phosphatase type IVA 3 (Precursor) GN=PTP4A3 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: protein tyrosine phosphatase type IVA 3 [Galeopterus variegatus] 
ENSG00000184497(TMEM255B)	--	2.6578	53	2.809902	40	1.174412854	35	3.834273	51	2.557883229	41	1.213397068	40	0.977917311	-0.083849162	normal	0.980352559	0.013686273	normal	0.980020329	0.177187668	normal	0.991062151	0.021976192	normal	--	--	--	--	--	--	--	FAM70 protein	Transmembrane protein 255B GN=TMEM255B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 255B [Lipotes vexillifer]
ENSG00000184500(PROS1)	--	14.87126125	856	14.99770278	883	12.8295839	740	16.26057942	970	17.36590924	1020	17.90218843	1040	0.96811565	0.14928986	normal	0.960905699	0.186360086	normal	0.413138905	0.481860387	normal	0.142901771	0.268306807	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; 	"K03908|0|hsa:5627|PROS1, PROS, PS21, PS22, PS23, PS24, PS25, PSA, THPH5, THPH6; protein S (alpha); K03908 protein S (A)"	Complement and coagulation cascades (ko04610)	--	--	Laminin G domain;; Laminin G domain;; Coagulation Factor Xa inhibitory site;; Calcium-binding EGF domain;; Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain;; Complement Clr-like EGF-like;; EGF-like domain	Vitamin K-dependent protein S (Precursor) GN=PROS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: vitamin K-dependent protein S [Tursiops truncatus]
ENSG00000184507(NUTM1)	--	0.086140222	7	0	0	0.107690964	8	0.01228993	1	0.048042476	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	NUT protein N terminus;; NUT protein C terminal	NUT family member 1 GN=NUTM1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: NUT family member 1 isoform X2 [Equus przewalskii]
ENSG00000184508(HDDC3)	--	19.381811	525	18.36512	494	16.05025	441	15.690785	447	18.739766	509	18.89084058	549	0.919900557	-0.262042636	normal	0.970873987	0.021662726	normal	0.885393348	0.306791363	normal	0.956592571	0.023004075	normal	[TK]	Signal transduction mechanisms;; Transcription	--	"K01139|8.22522e-100|hsa:374659|HDDC3, (ppGpp)ase, MESH1; HD domain containing 3 (EC:3.1.7.2); K01139 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2] (A)"	Purine metabolism (ko00230)	[T]	Signal transduction mechanisms	HD domain;; HD domain	"Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 GN=HDDC3 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1 [Ailuropoda melanoleuca] "
ENSG00000184517(ZFP1)	--	4.463183345	258	4.977946261	285	4.480660426	261	4.972069908	299	4.624193563	253	3.938222713	237	0.950765441	0.180940595	normal	0.947151421	-0.192168057	normal	0.957406478	-0.146562634	normal	0.911176091	-0.049194922	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:162239|ZFP1, ZNF475; ZFP1 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain;; Zinc-finger of C2H2 type"	Zinc finger protein 1 homolog GN=ZFP1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 1 homolog isoform 2 [Orcinus orca]
ENSG00000184524(CEND1)	--	0.562857	19	1.5936	55	1.17241	41	0.496313	17	0.316352	10	0.805507	28	--	--	--	3.36E-05	-2.315123022	down	0.95435514	-0.534495662	normal	0.230873838	-1.083832072	normal	--	--	Biological Process: cerebellum development (GO:0021549);; Biological Process: neuron differentiation (GO:0030182);; 	--	--	--	--	--	Cell cycle exit and neuronal differentiation protein 1 GN=CEND1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: cell cycle exit and neuronal differentiation protein 1 isoform X1 [Tupaia chinensis] 
ENSG00000184530(C6orf58)	--	0.321898699	4	0.649818286	8	0.484913267	5	1.907992277	24	2.010206	25	2.767773	35	0.149740439	2.179898197	normal	0.681400041	1.459685269	normal	0.002025877	2.479988858	up	0.000371495	2.284326082	up	--	--	--	--	--	--	--	Mouse protein of unknown function (DUF781)	UPF0762 protein C6orf58 (Precursor) GN=C6orf58 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0762 protein C6orf58 homolog [Galeopterus variegatus]
ENSG00000184545(DUSP8)	--	1.71431108	127	1.74644006	131	1.64052853	131	2.5793936	192	1.74916319	134	1.66519964	124	0.557478485	0.559902057	normal	0.967236181	0.01111279	normal	0.966691172	-0.086491711	normal	0.677980916	0.187525858	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K04459|0|hsa:1850|DUSP8, C11orf81, HB5, HVH-5, HVH8; dual specificity phosphatase 8 (EC:3.1.3.16 3.1.3.48); K04459 dual specificity MAP kinase phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	MAPK signaling pathway (ko04010)	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Rhodanese-like domain"	Dual specificity protein phosphatase 8 GN=DUSP8 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: LOW QUALITY PROTEIN: dual specificity protein phosphatase 8 [Canis lupus familiaris]
ENSG00000184557(SOCS3)	--	14.13671106	524	12.87514048	579	15.83353123	626	18.68711798	995	12.59300883	581	19.22246554	723	5.08E-05	0.892368281	normal	0.972547011	-0.016408959	normal	0.952047632	0.199093651	normal	0.330400487	0.388829726	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	K04696|1.11193e-139|ptr:454921|SOCS3; suppressor of cytokine signaling 3; K04696 suppressor of cytokine signaling 3 (A)	Ubiquitin mediated proteolysis (ko04120);; Osteoclast differentiation (ko04380);; Jak-STAT signaling pathway (ko04630);; TNF signaling pathway (ko04668);; Insulin signaling pathway (ko04910);; Prolactin signaling pathway (ko04917);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hepatitis C (ko05160);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	SH2 domain;; SOCS box	Suppressor of cytokine signaling 3 GN=SOCS3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: suppressor of cytokine signaling 3 [Odobenus rosmarus divergens] 
ENSG00000184560(C17orf74)	--	0	0	0	0	0.04789729	0	0	0	0.0693433	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C17orf74 GN=C17orf74 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C17orf74 homolog [Galeopterus variegatus]
ENSG00000184564(SLITRK6)	--	3.27784	240	2.41461	173	2.95685	209	0.768116	56	1.78463	130	1.0093	74	5.77E-15	-2.100014829	down	0.826616147	-0.429341544	normal	1.27E-07	-1.487299741	down	0.000206788	-1.278490587	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat	SLIT and NTRK-like protein 6 (Precursor) GN=SLITRK6 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: SLIT and NTRK-like protein 6 [Galeopterus variegatus]
ENSG00000184574(LPAR5)	--	0.054387898	2	0.134419751	5	0.059552703	2	0.3002177	14	0.731641	32	0.182870088	9	--	--	--	0.009225023	2.345000149	up	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08390|0|hsa:57121|LPAR5, GPR92, GPR93, KPG_010, LPA5; lysophosphatidic acid receptor 5; K08390 lysophosphatidic acid receptor 5 (A)"	Rap1 signaling pathway (ko04015);; PI3K-Akt signaling pathway (ko04151);; Pathways in cancer (ko05200)	--	--	7 transmembrane receptor (rhodopsin family)	Lysophosphatidic acid receptor 5 GN=LPAR5 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: lysophosphatidic acid receptor 5 [Trichechus manatus latirostris]
ENSG00000184575(XPOT)	--	38.27126675	3662	44.73075863	3929	39.157745	3669	36.6825585	3472	38.93905209	3467	53.00337006	4971	0.989163717	-0.107650712	normal	0.980808513	-0.201818129	normal	0.745678994	0.429705031	normal	0.890153671	0.060765507	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	"K14288|0|ptr:452046|XPOT; exportin, tRNA; K14288 exportin-T (A)"	RNA transport (ko03013)	[YUJ]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport;; Translation, ribosomal structure and biogenesis"	Exportin 1-like protein;; Importin-beta N-terminal domain	Exportin-T GN=XPOT OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exportin-T isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000184584(TMEM173)	--	0.527512232	16	0.813887162	25	0.191774423	5	0.289349	7	0.449518452	13	0.619907408	19	--	--	--	0.939306293	-0.889085481	normal	--	--	--	--	--	--	--	--	Biological Process: activation of innate immune response (GO:0002218);; Biological Process: positive regulation of type I interferon production (GO:0032481);; 	K12654|0|ptr:462107|TMEM173; transmembrane protein 173; K12654 transmembrane protein 173 (A)	RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623)	--	--	Transmembrane protein 173	Stimulator of interferon genes protein GN=TMEM173 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: transmembrane protein 173 isoform 1 [Orcinus orca]
ENSG00000184588(PDE4B)	--	10.79521673	804	11.57240299	764	9.050911791	659	9.712625975	684	12.64486601	918	13.8257675	832	0.924055847	-0.263484795	normal	0.93844066	0.243055543	normal	0.86400163	0.327343638	normal	0.713453307	0.107408408	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K13293|0|ptr:456921|PDE4B; phosphodiesterase 4B, cAMP-specific; K13293 cAMP-specific phosphodiesterase 4 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; cAMP signaling pathway (ko04024);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase	"cAMP-specific 3',5'-cyclic phosphodiesterase 4B GN=PDE4B OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: cAMP-specific 3',5'-cyclic phosphodiesterase 4B isoform X1 [Eptesicus fuscus]"
ENSG00000184599(FAM19A3)	--	0	0	0	0	0	0	0.321150844	6	0.210759039	3	0.0536474	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TAFA family	Protein FAM19A3 (Precursor) GN=FAM19A3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM19A3 [Felis catus]
ENSG00000184602(SNN)	--	10.1998	589	11.0421	654	7.79763	458	5.53777	321	6.1095	350	5.77866	334	0.000140053	-0.903282561	normal	8.68E-05	-0.92040345	normal	0.575149303	-0.461996947	normal	0.000558715	-0.780760228	normal	--	--	--	--	--	--	--	Stannin transmembrane;; Stannin unstructured linker;; Stannin cytoplasmic	Stannin GN=SNN OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: stannin [Ochotona princeps] 
ENSG00000184611(KCNH7)	--	0.0942747	3	0	0	0.028201762	1	0	0	0.0304178	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04910|0|hsa:90134|KCNH7, ERG3, HERG3, Kv11.3; potassium voltage-gated channel, subfamily H (eag-related), member 7; K04910 potassium voltage-gated channel Eag-related subfamily H member 7 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; PAS domain;; Cyclic nucleotide-binding domain;; Ion channel;; PAS fold	Potassium voltage-gated channel subfamily H member 7 GN=KCNH7 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily H member 7 [Oryctolagus cuniculus]
ENSG00000184613(NELL2)	--	0.20364609	4	0.072720021	4	0.531357735	8	0	0	0.302218316	3	0.294593927	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Calcium-binding EGF domain;; von Willebrand factor type C domain;; EGF domain;; Complement Clr-like EGF-like;; Laminin G domain;; Concanavalin A-like lectin/glucanases superfamily;; EGF-like domain;; Laminin G domain	Protein kinase C-binding protein NELL2 (Precursor) GN=NELL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: protein kinase C-binding protein NELL2 [Ursus maritimus]
ENSG00000184619(KRBA2)	--	2.071279856	163	2.638937	234	1.699908999	150	1.536651688	138	1.901627688	148	1.89224087	155	0.936470842	-0.268283707	normal	0.164733547	-0.676787675	normal	0.967289962	0.03863112	normal	0.372059091	-0.332146003	normal	--	--	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	KRAB box	KRAB-A domain-containing protein 2 GN=KRBA2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: KRAB-A domain-containing protein 2 [Galeopterus variegatus]
ENSG00000184634(MED12)	--	6.314582513	977	7.174876693	925	6.6909753	915	6.077238167	763	6.306019959	996	5.788714564	879	0.752261009	-0.386817372	normal	0.975735329	0.085131673	normal	0.976628263	-0.066088567	normal	0.621092743	-0.115454514	normal	--	--	Molecular Function: RNA polymerase II transcription cofactor activity (GO:0001104);; Biological Process: regulation of transcription from RNA polymerase II promoter (GO:0006357);; Molecular Function: beta-catenin binding (GO:0008013);; Cellular Component: mediator complex (GO:0016592);; 	K15162|0|pps:100993721|MED12; mediator complex subunit 12; K15162 mediator of RNA polymerase II transcription subunit 12 (A)	Thyroid hormone signaling pathway (ko04919)	[K]	Transcription	Eukaryotic Mediator 12 subunit domain;; Eukaryotic Mediator 12 catenin-binding domain;; Transcription mediator complex subunit Med12	Mediator of RNA polymerase II transcription subunit 12 GN=MED12 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: mediator of RNA polymerase II transcription subunit 12 [Felis catus]
ENSG00000184635(ZNF93)	--	0	0	0.175015009	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:81931|ZNF93, HPF34, HTF34, TF34, ZNF505; zinc finger protein 93; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C1-like domain;; Rad4 beta-hairpin domain 1"	Zinc finger protein 93 GN=ZNF93 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000184640(SEPT9)	--	100.4885812	7980	94.97700574	7387	97.16939487	8238	125.1273133	9634	124.2779471	9669	94.60610889	7616	0.985947612	0.240871658	normal	0.934319881	0.366885727	normal	0.993794374	-0.12152888	normal	0.426227704	0.167860299	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	"K16938|0|hsa:10801|SEPT9, AF17q25, MSF, MSF1, NAPB, PNUTL4, SINT1, SeptD1; septin 9; K16938 septin 3/9/12 (A)"	Bacterial invasion of epithelial cells (ko05100)	[DTZ]	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms;; Cytoskeleton"	"Septin;; 50S ribosome-binding GTPase;; Protein of unknown function, DUF258;; Dynamin family;; AIG1 family;; Elongation factor Tu GTP binding domain"	Septin-9 GN=SEPT9 OS=Homo sapiens (Human) PE=1 SV=2	DTZ	"Cell cycle control, cell division, chromosome partitioning;; Signal transduction mechanisms;; Cytoskeleton"	PREDICTED: septin-9 isoform X2 [Mustela putorius furo]
ENSG00000184659(FOXD4L4)	--	0.0269304	1	0.0266467	1	0	0	0.213709	8	0.0778422	2	0.0790218	3	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09397|0|hsa:349334|FOXD4L4, FOXD4L2, FOXD4b, bA460E7.2; forkhead box D4-like 4; K09397 forkhead box protein D (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein D4-like 4 GN=FOXD4L4 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: forkhead box protein D4-like [Equus przewalskii]
ENSG00000184661(CDCA2)	--	17.460421	1501	13.786174	1309	17.25950889	1529	16.190947	1430	13.847419	1221	12.72067536	1165	0.980377773	-0.100635537	normal	0.976228123	-0.121682857	normal	0.73225587	-0.400095094	normal	0.262129536	-0.206971334	normal	--	--	--	"K17590|0|hsa:157313|CDCA2, PPP1R81, Repo-Man; cell division cycle associated 2; K17590 cell division cycle-associated protein 2 (A)"	--	--	--	Protein phosphatase 1 binding	Cell division cycle-associated protein 2 GN=CDCA2 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cell division cycle-associated protein 2 isoform X1 [Galeopterus variegatus] 
ENSG00000184672(RALYL)	--	0	0	0	0	0	0	0.0477174	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding Raly-like protein GN=RALYL OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: RNA-binding Raly-like protein-like isoform X1 [Elephantulus edwardii]
ENSG00000184675(AMER1)	--	1.8402779	329	1.757846	306	1.695442211	305	1.518784428	271	1.568862678	279	1.507705424	271	0.891697458	-0.30903385	normal	0.955082267	-0.153896206	normal	0.951505584	-0.177871609	normal	0.466156679	-0.216504541	normal	--	--	--	--	--	--	--	WTX protein	APC membrane recruitment protein 1 GN=AMER1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: APC membrane recruitment protein 1 [Oryctolagus cuniculus]
ENSG00000184677(ZBTB40)	--	4.149058584	778	4.739436637	886	4.375852933	815	4.12602181	766	5.356943	994	6.25175721	1166	0.975365139	-0.053152237	normal	0.968998332	0.14428	normal	0.304847336	0.507612838	normal	0.508055554	0.219189534	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10512|0|hsa:9923|ZBTB40, ZNF923; zinc finger and BTB domain containing 40; K10512 zinc finger and BTB domain-containing protein 40 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; BTB/POZ domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger and BTB domain-containing protein 40 GN=ZBTB40 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 40 [Galeopterus variegatus]
ENSG00000184678(HIST2H2BE)	--	7.51422	214	7.20432	204	8.55092	242	3.29629	94	2.94546	83	6.24228	178	3.19E-05	-1.204282909	down	8.17E-06	-1.30314764	down	0.738839623	-0.448142741	normal	0.007079752	-0.913608791	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|6.02392e-60|pss:102451988|histone H2B 8-like; K11252 histone H2B (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 2-E GN=HIST2H2BE OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5-like [Bubalus bubalis]
ENSG00000184697(CLDN6)	--	0	0	0.102013	2	0	0	0.156166	3	0.103063	1	0.104498	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|6.54837e-116|ptr:467882|CLDN6; claudin 6; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-6 GN=CLDN6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: claudin-6 [Eptesicus fuscus]
ENSG00000184702(SEPT5)	--	6.786317964	314	4.568514799	271	6.408034373	308	5.660280882	286	5.972636089	287	3.70918262	232	0.954106533	-0.16473663	normal	0.96490421	0.061000529	normal	0.76145808	-0.414742554	normal	0.595231857	-0.171295525	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Molecular Function: GTP binding (GO:0005525);; 	K04557|0|mcc:712041|SEPT5; septin 5; K04557 septin 5 (A)	Parkinson's disease (ko05012)	[DZU]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	"Septin;; 50S ribosome-binding GTPase;; Protein of unknown function, DUF258;; Elongation factor Tu GTP binding domain"	Septin-5 GN=SEPT5 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: septin-5 [Galeopterus variegatus] 
ENSG00000184708(EIF4ENIF1)	--	5.807940499	379	6.947467467	370	10.40298303	376	4.868333911	372	5.627487838	381	7.862838498	320	0.967717295	-0.05749223	normal	0.968187353	0.020755571	normal	0.931597417	-0.239905062	normal	0.792791575	-0.089842883	normal	--	--	--	"K18728|0|hsa:56478|EIF4ENIF1, 4E-T, Clast4; eukaryotic translation initiation factor 4E nuclear import factor 1; K18728 eukaryotic translation initiation factor 4E transporter (A)"	--	--	--	Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E	Eukaryotic translation initiation factor 4E transporter GN=EIF4ENIF1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4E transporter isoform 2 [Ceratotherium simum simum] 
ENSG00000184709(LRRC26)	--	2.98212	36	2.28674	29	2.50986	32	3.24667	40	4.04903	49	1.87095	23	0.981568237	0.116454598	normal	0.880167443	0.706669205	normal	0.973301548	-0.459033627	normal	0.835971011	0.185116752	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 26 (Precursor) GN=LRRC26 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 26 [Canis lupus familiaris]
ENSG00000184716(SERINC4)	--	1.202710409	50	1.45799	61	0.824354	35	1.71105	71	1.64204	68	1.688690091	71	0.927995554	0.463066633	normal	0.971860589	0.132193907	normal	0.298816684	0.981810145	normal	0.340078191	0.502413999	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[S]	Function unknown	Serine incorporator (Serinc)	Serine incorporator 4 GN=SERINC4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: serine incorporator 4 [Myotis davidii]
ENSG00000184719(RNLS)	--	4.383529802	121	3.564423886	122	3.404048401	82	6.48117486	190	5.6462769	171	6.691678085	181	0.414995218	0.613892581	normal	0.792080348	0.460843072	normal	0.00055909	1.119751181	up	0.019529334	0.715822086	normal	[R]	General function prediction only	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K18208|0|hsa:55328|RNLS, C10orf59, RENALASE; renalase, FAD-dependent amine oxidase (EC:1.6.3.5); K18208 renalase [EC:1.6.3.5] (A)"	--	--	--	NAD(P)-binding Rossmann-like domain;; Flavin containing amine oxidoreductase;; FAD-NAD(P)-binding	Renalase (Precursor) GN=RNLS OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: renalase isoform X1 [Tupaia chinensis]
ENSG00000184730(APOBR)	--	0.019354328	2	0.018034537	2	0.03576561	3	0.018929457	2	0.018921533	1	0.0479298	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Apolipoprotein B receptor GN=APOBR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: apolipoprotein B receptor [Ursus maritimus]
ENSG00000184731(FAM110C)	--	1.815807	119	1.473119643	98	1.579839828	104	0.6203188	41	0.589385547	39	0.534835211	34	2.22E-05	-1.532776309	down	0.002342907	-1.317378959	down	5.08E-05	-1.579076278	down	5.35E-05	-1.515301429	down	--	--	--	--	--	--	--	Centrosome-associated C terminus;; Centrosome-associated N terminus	Protein FAM110C GN=FAM110C OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM110C [Orcinus orca]
ENSG00000184735(DDX53)	--	0.0308525	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; Molecular Function: ATP binding (GO:0005524);; 	--	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; KH domain;; KH domain;; Type III restriction enzyme, res subunit"	Probable ATP-dependent RNA helicase DDX53 GN=DDX53 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX53 [Camelus ferus] 
ENSG00000184743(ATL3)	--	16.63101173	1739	18.960268	1905	18.68918986	1771	17.948655	1892	14.70263681	1523	16.57570134	1727	0.983520817	0.090745017	normal	0.874310973	-0.343995483	normal	0.985059967	-0.044549047	normal	0.670679714	-0.096263547	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K17339|0|nle:100593382|ATL3; atlastin GTPase 3; K17339 atlastin [EC:3.6.5.-] (A)	--	[R]	General function prediction only	"Guanylate-binding protein, N-terminal domain;; Guanylate-binding protein, C-terminal domain"	Atlastin-3 GN=ATL3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: atlastin-3 isoform X1 [Galeopterus variegatus]
ENSG00000184752(NDUFA12)	--	73.11096	529	71.26326	542	81.49941	610	86.44644	640	76.32198	546	72.9369	541	0.931981217	0.243328651	normal	0.971901808	-0.010788467	normal	0.955018194	-0.180995307	normal	0.965782714	0.017432823	normal	[C]	Energy production and conversion	Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; Molecular Function: electron carrier activity (GO:0009055);; Cellular Component: membrane (GO:0016020);; 	"K11352|5.82298e-104|ptr:452134|NDUFA12; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12; K11352 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 12 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	NADH ubiquinone oxidoreductase subunit NDUFA12	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 GN=NDUFA12 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 isoform X1 [Lipotes vexillifer]
ENSG00000184785(SMIM10)	--	0	0	0	0	0	0	0.222287	6	0.10851	2	0.0735996	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4560)	Small integral membrane protein 10 GN=SMIM10 OS=Homo sapiens (Human) PE=4 SV=4	S	Function unknown	"hypothetical protein M91_16829, partial [Bos mutus]"
ENSG00000184787(UBE2G2)	--	21.24288896	1812	19.88948722	1743	20.97872298	1760	24.07614862	1918	23.3888895	1932	21.52869891	1929	0.985496558	0.051145349	normal	0.980648623	0.126991282	normal	0.981317084	0.123884563	normal	0.654520284	0.09957575	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K04555|9.61427e-120|tup:102489253|UBE2G2; ubiquitin-conjugating enzyme E2G 2; K04555 ubiquitin-conjugating enzyme E2 G2 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 G2 GN=UBE2G2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 G2 [Elephantulus edwardii]
ENSG00000184788(SATL1)	--	0.0356115	2	0.198575	11	0.088103214	4	0.0358117	2	0.12017	6	0.0350126	2	--	--	--	--	--	--	--	--	--	--	--	--	[KR]	Transcription;; General function prediction only	--	--	--	--	--	--	Spermidine/spermine N(1)-acetyltransferase-like protein 1 GN=SATL1 OS=Homo sapiens (Human) PE=2 SV=3	E	Amino acid transport and metabolism	PREDICTED: spermidine/spermine N(1)-acetyltransferase-like protein 1-like [Tupaia chinensis]
ENSG00000184792(OSBP2)	--	4.248712798	281	5.12282786	364	4.940170173	318	4.368482052	292	3.447733762	213	2.7958158	194	0.967343332	0.024434914	normal	0.009518226	-0.790166318	normal	0.045293574	-0.716851884	normal	0.064182556	-0.484857137	normal	--	--	--	--	--	[I]	Lipid transport and metabolism	Oxysterol-binding protein;; PH domain;; Pleckstrin homology domain;; Pleckstrin homology domain	Oxysterol-binding protein 2 GN=OSBP2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: oxysterol-binding protein 2 isoform X4 [Galeopterus variegatus]
ENSG00000184828(ZBTB7C)	--	0.044468785	4	0.055441802	5	0.076013124	6	0.05592056	5	0.010829337	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10494|0|hsa:201501|ZBTB7C, APM-1, APM1, ZBTB36, ZNF857C; zinc finger and BTB domain containing 7C; K10494 zinc finger and BTB domain-containing protein 7 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc finger, C2H2 type"	Zinc finger and BTB domain-containing protein 7C GN=ZBTB7C OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 7C isoform X1 [Mustela putorius furo] 
ENSG00000184831(APOO)	--	21.760971	336	21.06755547	304	22.77877838	333	24.77645408	397	23.84593872	379	25.91441581	391	0.943068395	0.208965695	normal	0.89913228	0.295381684	normal	0.938581775	0.222421884	normal	0.361175068	0.241134403	normal	--	--	Biological Process: cristae formation (GO:0042407);; Cellular Component: MICOS complex (GO:0061617);; 	--	--	[S]	Function unknown	Apolipoprotein O	Apolipoprotein O (Precursor) GN=APOO OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: apolipoprotein O [Equus caballus]
ENSG00000184838(PRR16)	--	0.090162453	3	0.231870559	3	0.080921452	1	0.280825333	8	0.777288703	10	0.133229343	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4589)	Protein Largen GN=PRR16 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: proline-rich protein 16 [Orycteropus afer afer]
ENSG00000184840(TMED9)	--	116.461	3104	116.69	3245	101.601	2818	139.827	3824	141.057	3720	137.776	3708	0.961904869	0.270001121	normal	0.983481239	0.175581115	normal	0.833379717	0.387496361	normal	0.103671703	0.274156242	normal	--	--	Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	emp24/gp25L/p24 family/GOLD	Transmembrane emp24 domain-containing protein 9 (Precursor) GN=TMED9 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: transmembrane emp24 domain-containing protein 9-like isoform X1 [Leptonychotes weddellii]
ENSG00000184845(DRD1)	--	5.117778	350	4.076909	274	4.233246	275	0.66131278	44	1.202281481	79	0.57736076	39	0	-2.978824565	down	2.60E-12	-1.796002284	down	0	-2.779026126	down	5.95E-21	-2.493616892	down	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04144|0|ptr:744598|DRD1; dopamine receptor D1; K04144 dopamine receptor D1 (A)	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Gap junction (ko04540);; Dopaminergic synapse (ko04728);; Parkinson's disease (ko05012);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Morphine addiction (ko05032);; Alcoholism (ko05034)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	D(1A) dopamine receptor GN=DRD1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: D(1A) dopamine receptor isoform X1 [Canis lupus familiaris] 
ENSG00000184857(TMEM186)	--	7.986020052	188	8.227662	199	7.271830712	174	8.647334	207	8.09252	189	8.17477	193	0.962576279	0.107230516	normal	0.962370898	-0.095067315	normal	0.959535198	0.140065768	normal	0.925424233	0.048637558	normal	--	--	--	--	--	--	--	Transmembrane protein 223	Transmembrane protein 186 GN=TMEM186 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 186 [Galeopterus variegatus]
ENSG00000184860(SDR42E1)	--	0.616993938	47	0.302871055	47	0.304527674	46	0.480302718	94	0.74766792	81	0.926534942	128	0.160077984	0.946885958	normal	0.631219851	0.745362516	normal	5.25E-05	1.438605314	up	0.00495854	1.093548542	up	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	"Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-beta-hydroxy-delta5-steroid dehydrogenase activity (GO:0003854);; Biological Process: steroid biosynthetic process (GO:0006694);; Molecular Function: oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor (GO:0016616);; Molecular Function: coenzyme binding (GO:0050662);; Biological Process: oxidation-reduction process (GO:0055114);; "	--	--	[IE]	Lipid transport and metabolism;; Amino acid transport and metabolism	3-beta hydroxysteroid dehydrogenase/isomerase family;; NAD dependent epimerase/dehydratase family;; RmlD substrate binding domain;; Male sterility protein;; NADH(P)-binding;; Polysaccharide biosynthesis protein	Short-chain dehydrogenase/reductase family 42E member 1 GN=SDR42E1 OS=Homo sapiens (Human) PE=2 SV=2	EI	Amino acid transport and metabolism;; Lipid transport and metabolism	PREDICTED: short-chain dehydrogenase/reductase family 42E member 1 isoform X2 [Canis lupus familiaris] 
ENSG00000184863(RBM33)	--	13.63790349	1423	12.10493733	1469	12.71032466	1380	13.91882108	1381	15.08405997	1618	13.69129522	1480	0.981522147	-0.073973523	normal	0.97925387	0.117835038	normal	0.980692276	0.092539526	normal	0.861244838	0.047255818	normal	--	--	--	--	--	--	--	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 33 GN=RBM33 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: RNA-binding protein 33 [Canis lupus familiaris]
ENSG00000184867(ARMCX2)	--	0	0	0	0	0	0	0.079514407	4	0.151713967	5	0.332250834	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Armadillo-like;; Armadillo/beta-catenin-like repeat	Armadillo repeat-containing X-linked protein 2 GN=ARMCX2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: armadillo repeat-containing X-linked protein 2 [Galeopterus variegatus] 
ENSG00000184887(BTBD6)	--	15.87683	563	16.61472001	601	17.17336	631	18.95945	691	20.47904	729	19.64486062	722	0.920951274	0.264067152	normal	0.926865915	0.256540385	normal	0.955966196	0.185651147	normal	0.263746433	0.234071641	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10478|0|hsa:90135|BTBD6, BDPL; BTB (POZ) domain containing 6; K10478 BTB/POZ domain-containing protein 3/6 (A)"	--	[S]	Function unknown	PHR domain;; BTB/POZ domain;; BTB And C-terminal Kelch	BTB/POZ domain-containing protein 6 GN=BTBD6 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	"PREDICTED: BTB/POZ domain-containing protein 6, partial [Equus caballus]"
ENSG00000184897(H1FX)	--	165.062	3522	115.466	2513	130.593	2895	137.288	2942	147.76	3196	152.265	3288	0.950204667	-0.290291138	normal	0.921700846	0.325256252	normal	0.982229234	0.175269545	normal	0.86011184	0.057147699	normal	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11275|1.14558e-75|mcf:102131764|histone H1x-like; K11275 histone H1/5 (A)	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	Histone H1x GN=H1FX OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone H1x-like [Pteropus alecto] 
ENSG00000184898(RBM43)	--	5.134841	268	3.995382	259	3.385082	225	3.345723	218	2.814402	180	2.806627	192	0.885921071	-0.326656356	normal	0.479856397	-0.542559312	normal	0.938812093	-0.235395501	normal	0.1990821	-0.371936876	normal	--	--	--	--	--	--	--	--	RNA-binding protein 43 GN=RBM43 OS=Homo sapiens (Human) PE=2 SV=1	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: RNA-binding protein 43 [Galeopterus variegatus]
ENSG00000184900(SUMO3)	--	34.737829	1035	37.52086404	1134	37.67577509	1130	48.75818847	1467	46.27936679	1373	42.59123348	1273	0.45281708	0.471814929	normal	0.942327952	0.254175983	normal	0.970081383	0.163412049	normal	0.07819642	0.296601538	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K12160|1.4409e-48|nle:100587904|SUMO3; SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae); K12160 small ubiquitin-related modifier (A)	RNA transport (ko03013)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin family	Small ubiquitin-related modifier 3 {ECO:0000305} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	small ubiquitin-related modifier 3 precursor [Bos taurus] 
ENSG00000184903(IMMP2L)	--	22.90447002	165	7.079345035	137	6.492309739	127	46.27673754	240	85.55298301	286	55.73158013	279	0.613312884	0.505810892	normal	0.000221511	1.032356398	up	3.38E-05	1.117937348	up	0.000329578	0.887060495	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	--	K09648|2.14057e-125|pon:100433906|IMMP2L; IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae); K09648 mitochondrial inner membrane protease subunit 2 [EC:3.4.21.-] (A)	Protein export (ko03060)	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	"Peptidase S24-like;; Signal peptidase, peptidase S26"	Mitochondrial inner membrane protease subunit 2 GN=IMMP2L OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial inner membrane protease subunit 2 isoform X2 [Canis lupus familiaris] 
ENSG00000184905(TCEAL2)	--	0.0330155	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Brain expressed X-linked like family	Transcription elongation factor A protein-like 2 GN=TCEAL2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription elongation factor A protein-like 2 isoform X1 [Tupaia chinensis] 
ENSG00000184908(CLCNKB)	--	0.30207952	11	0.086847235	4	0.052995839	1	0	0	0.10728502	3	0.080456939	2	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05018|0|hsa:1188|CLCNKB, CLCKB, ClC-K2, ClC-Kb; chloride channel, voltage-sensitive Kb; K05018 chloride channel Kb (A)"	Collecting duct acid secretion (ko04966)	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	Chloride channel protein ClC-Kb GN=CLCNKB OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: chloride channel protein ClC-Ka isoform X2 [Eptesicus fuscus]
ENSG00000184922(FMNL1)	--	21.40209917	1475	22.16796522	1513	22.9548241	1558	16.33948518	1200	14.9030793	1113	17.9847396	1340	0.880122493	-0.328133059	normal	0.511486744	-0.463842084	normal	0.957802122	-0.225517399	normal	0.036880813	-0.33634307	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain	Formin-like protein 1 GN=FMNL1 OS=Homo sapiens (Human) PE=1 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	Formin-like protein 3 [Tupaia chinensis]
ENSG00000184923(NUTM2A)	--	0.377138	30	0.521206	41	0.1779261	14	0.1483914	12	0.3172	25	0.229604	19	0.714106115	-1.248501321	normal	0.913327533	-0.701653137	normal	--	--	--	0.507391763	-0.623260912	normal	--	--	--	--	--	--	--	NUT protein N terminus;; NUT protein C terminal	NUT family member 2A GN=NUTM2A OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: NUT family member 2G-like [Equus caballus]
ENSG00000184924(PTRHD1)	--	13.7743	198	14.9447	218	14.8322	215	9.64923	142	9.26066	133	11.9172	173	0.668354455	-0.505783633	normal	0.104419754	-0.727796031	normal	0.902925465	-0.31934684	normal	0.082267215	-0.514733705	normal	--	--	Molecular Function: aminoacyl-tRNA hydrolase activity (GO:0004045);; 	--	--	[S]	Function unknown	Peptidyl-tRNA hydrolase PTH2	Putative peptidyl-tRNA hydrolase PTRHD1 GN=PTRHD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: putative peptidyl-tRNA hydrolase PTRHD1 [Galeopterus variegatus]
ENSG00000184925(LCN12)	--	2.193180117	94	1.921861361	85	1.082432815	53	0.672953565	13	0.717796478	24	0.894505377	51	5.74E-11	-2.745329612	down	3.42E-05	-1.782317065	down	0.977914101	-0.061983458	normal	0.017416517	-1.416736447	normal	--	--	--	--	--	--	--	Lipocalin / cytosolic fatty-acid binding protein family	Epididymal-specific lipocalin-12 (Precursor) GN=LCN12 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: epididymal-specific lipocalin-12 isoform X1 [Tupaia chinensis]
ENSG00000184937(WT1)	--	2.625273126	126	2.34050127	117	2.113750282	99	2.721110745	130	3.561935371	148	1.591824799	81	0.968854089	0.014086523	normal	0.923333923	0.314045913	normal	0.94862047	-0.292844078	normal	0.946734065	0.047391557	normal	[R]	General function prediction only	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09234|0|hsa:7490|WT1, AWT1, EWS-WT1, GUD, NPHS4, WAGR, WIT-2, WT33; Wilms tumor 1; K09234 Wilms tumor protein 1 (A)"	Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"Wilm's tumour protein;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Wilms tumor protein GN=WT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: Wilms tumor protein [Bubalus bubalis]
ENSG00000184939(ZFP90)	--	8.639281206	768	7.253378567	625	35.06518427	795	10.7524728	912	10.30081229	778	9.6240513	843	0.949485136	0.216697065	normal	0.901086213	0.293849044	normal	0.974899763	0.076145649	normal	0.36710422	0.19002426	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:146198|ZFP90, FIK, NK10, ZNF756; ZFP90 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 90 homolog GN=ZFP90 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 90 homolog [Ceratotherium simum simum]
ENSG00000184949(FAM227A)	--	0.84057786	176	0.8224263	166	0.794199005	151	0.891939893	176	0.815260574	168	0.583180625	109	0.966940685	-0.030565438	normal	0.966147578	-0.004111336	normal	0.801888478	-0.472912293	normal	0.754561271	-0.144738457	normal	--	--	--	--	--	--	--	Protein of unknown function	Protein FAM227A GN=FAM227A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM227A [Ceratotherium simum simum]
ENSG00000184956(MUC6)	--	0.0874849	16	0.095978	17	0.05427676	9	0.0785994	14	0.0686592	12	0.0968606	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type D domain;; C8 domain;; Trypsin Inhibitor like cysteine rich domain	Mucin-6 (Precursor) GN=MUC6 OS=Homo sapiens (Human) PE=1 SV=3	VW	Defense mechanisms;; Extracellular structures	PREDICTED: mucin-6 [Galeopterus variegatus]
ENSG00000184967(NOC4L)	--	21.04890601	569	21.70660565	594	20.12680291	558	27.16430872	737	28.02644466	754	19.95250782	544	0.841519431	0.341591372	normal	0.871594287	0.321946034	normal	0.971960924	-0.044826865	normal	0.350283491	0.219728374	normal	--	--	--	"K14771|0|hsa:79050|NOC4L, NET49, NOC4, UTP19; nucleolar complex associated 4 homolog (S. cerevisiae); K14771 U3 small nucleolar RNA-associated protein 19 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	CBF/Mak21 family	Nucleolar complex protein 4 homolog GN=NOC4L OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: nucleolar complex protein 4 homolog [Camelus dromedarius]
ENSG00000184979(USP18)	--	3.338368	143	2.759212	119	3.156237343	136	4.560982	195	3.920446	166	3.887288	166	0.832602324	0.412815587	normal	0.807110651	0.453891263	normal	0.933631224	0.276497963	normal	0.272111001	0.383409776	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11846|0|hsa:11274|USP18, ISG43, UBP43; ubiquitin specific peptidase 18; K11846 ubiquitin carboxyl-terminal hydrolase 18/41 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubl carboxyl-terminal hydrolase 18 GN=USP18 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubl carboxyl-terminal hydrolase 18 [Galeopterus variegatus]
ENSG00000184983(NDUFA6)	--	36.38523514	558	39.46399502	624	37.79482548	585	35.04614	533	35.70673847	548	36.14619096	551	0.968265967	-0.096689406	normal	0.946594888	-0.208257657	normal	0.969053674	-0.094424189	normal	0.59832271	-0.135780712	normal	--	--	--	"K03950|1.71154e-111|pps:100993915|NDUFA6; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa; K03950 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 6 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Complex 1 protein (LYR family);; Complex1_LYR-like	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 GN=NDUFA6 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 [Bos mutus]
ENSG00000184984(CHRM5)	--	0.02108155	2	0.08423451	8	0.052368201	4	0.03171864	3	0.0737433	3	0.0418975	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04133|0|hsa:1133|CHRM5, HM5; cholinergic receptor, muscarinic 5; K04133 muscarinic acetylcholine receptor M5 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Cholinergic synapse (ko04725);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Muscarinic acetylcholine receptor M5 GN=CHRM5 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	Muscarinic acetylcholine receptor M5 [Tupaia chinensis]
ENSG00000184985(SORCS2)	--	1.88458395	189	1.238771104	73	1.546407875	133	0.548835204	46	0.965738212	61	0.596602361	28	3.28E-12	-2.033170032	down	0.959930901	-0.274288512	normal	1.41E-10	-2.196382682	down	0.040829495	-1.570822791	normal	--	--	--	--	--	[R]	General function prediction only	PKD domain	VPS10 domain-containing receptor SorCS2 (Precursor) GN=SORCS2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	"PREDICTED: VPS10 domain-containing receptor SorCS2, partial [Odobenus rosmarus divergens]"
ENSG00000184986(TMEM121)	--	15.67234814	295	9.138758012	180	9.565672299	191	14.67144504	283	11.50984362	218	6.419187908	122	0.964032642	-0.090265113	normal	0.932383558	0.252970986	normal	0.310586161	-0.648504069	normal	0.895946735	-0.120074315	normal	--	--	--	--	--	--	--	CECR6/TMEM121 family	Transmembrane protein 121 GN=TMEM121 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	TPA: hole protein-like [Bos taurus]
ENSG00000184988(TMEM106A)	--	0.886513927	82	1.866142546	99	1.541565383	136	1.574740851	127	0.968156627	97	1.034830893	92	0.674794666	0.591335173	normal	0.969181012	-0.050097201	normal	0.688519377	-0.564511485	normal	0.978047425	-0.026080573	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1356)	Transmembrane protein 106A GN=TMEM106A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 106A [Ursus maritimus]
ENSG00000184990(SIVA1)	--	92.13202716	846	93.887218	973	92.54863001	930	117.7834048	1089	109.6043204	993	90.87375128	872	0.861669689	0.332908062	normal	0.978859517	0.007915178	normal	0.974156844	-0.101024337	normal	0.742517122	0.081922087	normal	--	--	--	--	--	--	--	Cd27 binding protein (Siva)	Apoptosis regulatory protein Siva GN=SIVA1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: apoptosis regulatory protein Siva isoform X2 [Galeopterus variegatus]
ENSG00000184992(BRI3BP)	--	18.60477	2034	20.27751	2235	20.66275	2249	22.02473	2419	16.87386	1836	17.55291	1918	0.968761175	0.219106918	normal	0.925098192	-0.304907284	normal	0.961724075	-0.237799036	normal	0.667417991	-0.10039185	normal	--	--	--	--	--	--	--	Negative regulator of p53/TP53	BRI3-binding protein OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: BRI3-binding protein [Oryctolagus cuniculus]
ENSG00000184995(IFNE)	--	0.915756	44	2.089155	75	2.760101	80	2.75047	104	3.66577	146	3.64328	124	0.008811322	1.182559485	up	0.034352256	0.925966779	normal	0.634956713	0.614574569	normal	0.013265344	0.890158136	normal	--	--	Molecular Function: cytokine receptor binding (GO:0005126);; Cellular Component: extracellular region (GO:0005576);; Biological Process: defense response (GO:0006952);; 	"K05442|3.8026e-150|hsa:338376|IFNE, IFN-E, IFNE1, IFNT1, INFE1, PRO655; interferon, epsilon; K05442 interferon, tau-1 (A)"	Cytokine-cytokine receptor interaction (ko04060);; RIG-I-like receptor signaling pathway (ko04622);; Jak-STAT signaling pathway (ko04630)	--	--	Interferon alpha/beta domain	Interferon epsilon (Precursor) GN=IFNE OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: interferon epsilon [Galeopterus variegatus]
ENSG00000185000(DGAT1)	--	21.2559	728	15.02957	607	18.62399	706	16.80134	586	18.5387	647	20.30476	690	0.839025183	-0.343061173	normal	0.971359924	0.070472563	normal	0.974745309	-0.041273831	normal	0.682408658	-0.10646073	normal	[I]	Lipid transport and metabolism	--	K11155|0|ptr:464460|DGAT1; diacylglycerol O-acyltransferase 1; K11155 diacylglycerol O-acyltransferase 1 [EC:2.3.1.20 2.3.1.75 2.3.1.76] (A)	Glycerolipid metabolism (ko00561);; Retinol metabolism (ko00830);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	"MBOAT, membrane-bound O-acyltransferase family"	Diacylglycerol O-acyltransferase 1 GN=DGAT1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: diacylglycerol O-acyltransferase 1 [Erinaceus europaeus]
ENSG00000185009(AP3M1)	--	37.08915	2219	37.40806	2196	37.84044	2242	33.95806	2009	30.66336	1852	34.42003	2030	0.977129153	-0.174137576	normal	0.949195876	-0.267019997	normal	0.980347006	-0.151490556	normal	0.278591328	-0.197523961	normal	--	--	--	"K12398|0|cjc:100406271|AP3M1; adaptor-related protein complex 3, mu 1 subunit; K12398 AP-3 complex subunit mu (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family;; Clathrin adaptor complex small chain	AP-3 complex subunit mu-1 GN=AP3M1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-3 complex subunit mu-1 isoform X1 [Orycteropus afer afer]
ENSG00000185010(F8)	--	9.130542756	404	8.852483	378	9.007908722	398	3.58777216	160	3.72947679	174	4.516571362	200	3.34E-09	-1.358598928	down	3.89E-06	-1.133866111	down	7.12E-05	-0.995616697	normal	1.34E-08	-1.164344354	down	--	--	Molecular Function: copper ion binding (GO:0005507);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K03899|0|hsa:2157|F8, AHF, DXS1253E, F8B, F8C, FVIII, HEMA; coagulation factor VIII, procoagulant component; K03899 coagulation factor VIII (A)"	Complement and coagulation cascades (ko04610)	--	--	F5/8 type C domain;; Multicopper oxidase;; Multicopper oxidase;; Multicopper oxidase	Factor VIIIa light chain (Precursor) GN=F8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: coagulation factor VIII [Ceratotherium simum simum]
ENSG00000185013(NT5C1B)	--	27.56500008	659	25.41674214	627	26.60429956	648	24.4974893	595	25.01244855	597	21.87300008	525	0.956753379	-0.177784575	normal	0.969437475	-0.091933795	normal	0.88098006	-0.3111595	normal	0.396959279	-0.193199601	normal	--	--	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: magnesium ion binding (GO:0000287);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: 5'-nucleotidase activity (GO:0008253);; Biological Process: nucleotide metabolic process (GO:0009117);; 	"K01081|0|hsa:93034|NT5C1B, AIRP, CN-IB, CN1B; 5'-nucleotidase, cytosolic IB (EC:3.1.3.5); K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	--	--	5'-nucleotidase	Cytosolic 5'-nucleotidase 1B GN=NT5C1B OS=Homo sapiens (Human) PE=2 SV=2	F	Nucleotide transport and metabolism	PREDICTED: cytosolic 5'-nucleotidase 1B isoform X3 [Ailuropoda melanoleuca]
ENSG00000185015(CA13)	--	1.008562	52	0.735301	38	0.637845	32	0.69978	36	0.989525	50	0.92313933	49	0.933708491	-0.541987828	normal	0.964034849	0.361913224	normal	0.929332054	0.583963959	normal	0.892271804	0.125359279	normal	[P]	Inorganic ion transport and metabolism	--	"K01672|0|hsa:377677|CA13, CAXIII; carbonic anhydrase XIII (EC:4.2.1.1); K01672 carbonic anhydrase [EC:4.2.1.1] (A)"	Nitrogen metabolism (ko00910)	[R]	General function prediction only	Eukaryotic-type carbonic anhydrase	Carbonic anhydrase 13 GN=CA13 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: carbonic anhydrase 13 isoform X1 [Oryctolagus cuniculus]
ENSG00000185019(UBOX5)	--	20.342085	1100	21.75865462	1155	18.97903098	1017	25.80794977	1358	26.43704258	1370	23.88361253	1274	0.930048699	0.27280425	normal	0.955100598	0.224586216	normal	0.889290036	0.31633304	normal	0.121475698	0.2689997	normal	--	--	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Biological Process: protein ubiquitination (GO:0016567);; 	K10600|0|ggo:101147961|UBOX5; RING finger protein 37 isoform 1; K10600 U-box domain-containing protein 5 (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	U-box domain	RING finger protein 37 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 37 isoform X1 [Camelus ferus] 
ENSG00000185022(MAFF)	--	3.661660022	174	3.97575	194	4.897150002	240	4.237271	192	2.856366	128	4.74572	227	0.962640015	0.1102597	normal	0.393676198	-0.615388891	normal	0.963889969	-0.088062894	normal	0.728697096	-0.172877179	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09037|2.02913e-82|pon:100445817|MAFF; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F; K09037 transcription factor MAFF/G/K (A)	--	[K]	Transcription	bZIP Maf transcription factor	Transcription factor MafF GN=MAFF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor MafF [Orycteropus afer afer]
ENSG00000185024(BRF1)	--	11.7862091	765	12.40135246	827	12.79195815	842	14.51631819	940	14.82733779	938	13.85123419	854	0.925237113	0.265886334	normal	0.965351062	0.159999177	normal	0.977650664	0.01210281	normal	0.515292743	0.145263006	normal	[K]	Transcription	Molecular Function: TBP-class protein binding (GO:0017025);; 	"K15196|0|ptr:453212|BRF1, ZFP36L1; BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit; K15196 transcription factor IIIB 90 kDa subunit (A)"	--	[K]	Transcription	"Transcription factor TFIIB repeat;; Brf1-like TBP-binding domain;; TFIIB zinc-binding;; Cyclin, N-terminal domain"	Transcription factor IIIB 90 kDa subunit GN=BRF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor IIIB 90 kDa subunit isoform 1 [Orcinus orca]
ENSG00000185028(LRRC14B)	--	0.121991	3	0	0	0.0764743	1	0.040389	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Leucine-rich repeat-containing protein 14B GN=LRRC14B OS=Homo sapiens (Human) PE=3 SV=3	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 14B [Galeopterus variegatus]
ENSG00000185033(SEMA4B)	--	90.61098479	6294	69.67669598	4936	76.77491494	5425	83.75289782	5791	62.64499197	4389	62.04552403	4385	0.990932775	-0.150958511	normal	0.98513696	-0.190814641	normal	0.949222682	-0.315239799	normal	0.416003696	-0.215600978	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06521|0|hsa:10509|SEMA4B, SEMAC, SemC; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B; K06521 semaphorin 4 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-4B (Precursor) GN=SEMA4B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: semaphorin-4B [Galeopterus variegatus]
ENSG00000185038(MROH2A)	--	0	0	0	0	0	0	0.008797982	1	0.04220685	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	HEAT repeat	Maestro heat-like repeat-containing protein family member 2A GN=MROH2A OS=Homo sapiens (Human) PE=4 SV=3	S	Function unknown	PREDICTED: maestro heat-like repeat-containing protein family member 2A [Galeopterus variegatus]
ENSG00000185040(SPDYE16)	--	1.04386131	58	1.353075587	79	1.357760306	78	0.6864812	40	0.7930109	44	0.890282498	50	0.919209759	-0.549259217	normal	0.450544005	-0.843822227	normal	0.8018267	-0.634352094	normal	0.143768799	-0.702439718	normal	--	--	--	--	--	--	--	Cell cycle regulatory protein	Speedy protein E2 GN=SPDYE2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: speedy protein E4-like [Dasypus novemcinctus]
ENSG00000185043(CIB1)	--	97.83235	2054	76.92259	1645	82.52126	1776	130.94531	2780	115.22866	2416	97.46746	2063	0.759782849	0.405554826	normal	0.242801963	0.532699927	normal	0.968888751	0.207656594	normal	0.063918121	0.38479541	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K17259|2.47215e-151|hsa:10519|CIB1, CIB, CIBP, KIP1, PRKDCIP, SIP2-28; calcium and integrin binding 1 (calmyrin); K17259 calcium and integrin-binding protein 1 (A)"	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair	Calcium and integrin-binding protein 1 GN=CIB1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: calcium and integrin-binding protein 1 [Ochotona princeps]
ENSG00000185046(ANKS1B)	--	1.30880112	62	1.8550202	75	1.39592557	82	2.4847519	88	1.980106	84	3.3083622	108	0.904178645	0.464695523	normal	0.968233888	0.139414933	normal	0.918154447	0.382873241	normal	0.511100179	0.334184981	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SAM domain (Sterile alpha motif);; Phosphotyrosine interaction domain (PTB/PID);; SAM domain (Sterile alpha motif);; Phosphotyrosine-binding domain	Ankyrin repeat and sterile alpha motif domain-containing protein 1B GN=ANKS1B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ankyrin repeat and sterile alpha motif domain-containing protein 1B isoform 1 [Ceratotherium simum simum]
ENSG00000185049(NELFA)	--	9.40460874	410	8.889950194	394	7.997373149	361	10.19033572	429	9.30100396	420	8.514077116	381	0.969563679	0.034395468	normal	0.966783589	0.070505012	normal	0.967045354	0.069218438	normal	0.876307067	0.056623953	normal	--	--	--	"K15179|0|ptr:461071|NELFA, WHSC2; negative elongation factor complex member A; K15179 negative elongation factor A (A)"	--	--	--	--	Negative elongation factor A GN=NELFA OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: negative elongation factor A [Ceratotherium simum simum]
ENSG00000185052(SLC24A3)	--	0.04390873	3	0	0	0	0	0.014635986	1	0.057176949	3	0.014581984	1	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13751|0|hsa:57419|SLC24A3, NCKX3; solute carrier family 24 (sodium/potassium/calcium exchanger), member 3; K13751 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Sodium/calcium exchanger protein	Sodium/potassium/calcium exchanger 3 (Precursor) GN=SLC24A3 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium/calcium exchanger 3 [Oryctolagus cuniculus]
ENSG00000185055(EFCAB10)	--	2.815383001	108	2.867641105	111	2.385885746	81	3.16359583	77	2.524517	65	2.748803995	101	0.833869212	-0.510291037	normal	0.32638091	-0.779428741	normal	0.945569662	0.30496166	normal	0.506662135	-0.324949323	normal	--	--	--	--	--	--	--	--	EF-hand calcium-binding domain-containing protein 10 GN=EFCAB10 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	EF-hand calcium-binding domain-containing protein 10 [Bos mutus]
ENSG00000185056(C5orf47)	--	0.0652698	2	0.193023	6	0	0	0	0	0	0	0.0322702	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C5orf47 GN=C5orf47 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C5orf47 homolog [Galeopterus variegatus]
ENSG00000185070(FLRT2)	--	0.03507832	5	0.00394522	2	0.03431894	5	2.646291577	327	3.019403662	410	3.694606583	458	0	5.624263861	up	0	6.855612619	up	0	6.133480241	up	1.06E-51	6.618502962	up	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K16362|0|nle:100584683|FLRT2; fibronectin leucine rich transmembrane protein 2; K16362 leucine-rich repeat transmembrane protein FLRT (A)	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Fibronectin type III domain;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Leucine-rich repeat transmembrane protein FLRT2 (Precursor) GN=FLRT2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: leucine-rich repeat transmembrane protein FLRT2 isoform 1 [Ceratotherium simum simum] 
ENSG00000185088(RPS27L)	--	228.55295	2275	272.86024	2906	284.5937	2922	294.02693	3004	244.1468659	2509	291.82923	3031	0.852338687	0.369967975	normal	0.96901228	-0.233218035	normal	0.989765616	0.044523606	normal	0.854325365	0.055381662	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02978|1.87168e-57|ggo:101137436|RPS27L; 40S ribosomal protein S27-like; K02978 small subunit ribosomal protein S27e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S27	40S ribosomal protein S27-like OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 40S ribosomal protein S27-like, partial [Ursus maritimus]"
ENSG00000185090(MANEAL)	--	15.73837277	791	18.02154249	820	16.5141885	803	15.98125155	762	14.03746816	698	15.50184027	766	0.973544572	-0.084551613	normal	0.931063135	-0.253316429	normal	0.974368615	-0.076200089	normal	0.55303736	-0.138197575	normal	--	--	"Molecular Function: hydrolase activity, acting on glycosyl bonds (GO:0016798);; "	--	--	--	--	--	"Glycoprotein endo-alpha-1,2-mannosidase-like protein GN=MANEAL OS=Homo sapiens (Human) PE=2 SV=1"	S	Function unknown	"PREDICTED: glycoprotein endo-alpha-1,2-mannosidase-like protein isoform X1 [Lipotes vexillifer]"
ENSG00000185100(ADSSL1)	--	5.333022751	187	3.725930677	131	4.171920672	142	2.587822996	96	5.426085314	182	2.18039	75	0.004116162	-0.981293696	normal	0.796733609	0.448534506	normal	0.040142347	-0.915576711	normal	0.551489232	-0.403409158	normal	[F]	Nucleotide transport and metabolism	Molecular Function: adenylosuccinate synthase activity (GO:0004019);; Molecular Function: GTP binding (GO:0005525);; Biological Process: purine nucleotide biosynthetic process (GO:0006164);; 	K01939|0|hsa:122622|ADSSL1; adenylosuccinate synthase like 1 (EC:6.3.4.4); K01939 adenylosuccinate synthase [EC:6.3.4.4] (A)	"Purine metabolism (ko00230);; Alanine, aspartate and glutamate metabolism (ko00250)"	[F]	Nucleotide transport and metabolism	Adenylosuccinate synthetase	Adenylosuccinate synthetase isozyme 1 {ECO:0000255|HAMAP-Rule:MF_03126} OS=Homo sapiens (Human) PE=2 SV=1	F	Nucleotide transport and metabolism	PREDICTED: adenylosuccinate synthetase isozyme 1 [Galeopterus variegatus]
ENSG00000185101(ANO9)	--	0.110558	5	0.0872197	4	0.170526	7	0.0880373	4	0.149499	6	0.0654812	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Calcium-activated chloride channel	Anoctamin-9 GN=ANO9 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: anoctamin-9 [Galeopterus variegatus]
ENSG00000185104(FAF1)	--	11.03914529	773	11.51842394	851	11.59764119	827	13.37416298	914	11.80358869	863	10.39563928	753	0.951772565	0.21050837	normal	0.977248489	-0.001222972	normal	0.967129648	-0.143254264	normal	0.942238902	0.024029122	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	UBX domain;; UBA-like domain	FAS-associated factor 1 GN=FAF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: FAS-associated factor 1 [Orycteropus afer afer]
ENSG00000185112(FAM43A)	--	1.07519	43	1.08677	45	0.916486	38	2.10109	85	2.50648	101	1.45081	59	0.254903769	0.928294245	normal	0.021289793	1.119192843	normal	0.894169318	0.60689758	normal	0.031518739	0.937111552	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Phosphotyrosine interaction domain (PTB/PID)	Protein FAM43A GN=FAM43A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM43A [Ceratotherium simum simum]
ENSG00000185115(NSMCE3)	--	10.8931	744	12.596	861	10.9938	742	11.7506	809	11.1307	761	11.0898	760	0.973108597	0.089826901	normal	0.95462329	-0.19917095	normal	0.976017915	0.026235954	normal	0.919574067	-0.032050078	normal	--	--	--	--	--	[S]	Function unknown	MAGE family	Melanoma-associated antigen G1 GN=NDNL2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: melanoma-associated antigen G1 [Galeopterus variegatus]
ENSG00000185122(HSF1)	--	41.360267	1784	39.38375	1702	41.81587082	1844	48.35496798	2070	44.18153002	1896	51.56579663	2220	0.974053308	0.183536053	normal	0.979676866	0.134188365	normal	0.952422983	0.259235555	normal	0.292798298	0.193960323	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09414|0|hsa:3297|HSF1, HSTF1; heat shock transcription factor 1; K09414 heat shock transcription factor 1 (A)"	Legionellosis (ko05134)	[K]	Transcription	Vertebrate heat shock transcription factor;; HSF-type DNA-binding	Heat shock factor protein 1 GN=HSF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: heat shock factor protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000185127(C6orf120)	--	14.60031	732	11.88748	571	13.68586	679	13.70794	669	12.69008	630	16.03087	799	0.962202644	-0.160317543	normal	0.966155619	0.120131543	normal	0.943777485	0.226027938	normal	0.848920384	0.061492689	normal	--	--	--	--	--	--	--	--	UPF0669 protein C6orf120 (Precursor) GN=C6orf120 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0669 protein C6orf120 homolog [Galeopterus variegatus]
ENSG00000185130(HIST1H2BL)	--	0.70399	3	0.454469	2	0.873212	3	1.73906	8	1.81189	7	1.35038	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K11252|4.0998e-61|hsa:8340|HIST1H2BL, H2B/c, H2BFC, dJ97D16.4; histone cluster 1, H2bl; K11252 histone H2B (A)"	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-L GN=HIST1H2BL OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2B type 1-L-like [Orcinus orca] 
ENSG00000185133(INPP5J)	--	1.137793046	63	0.792429525	39	0.500256827	29	0.766729748	30	1.408317537	81	0.90448678	63	0.260985018	-1.062807598	normal	0.16859676	1.005419126	normal	0.258087802	1.072194831	normal	0.692097736	0.389582962	normal	[T]	Signal transduction mechanisms	--	"K01106|0|pps:100980932|INPP5J; inositol polyphosphate-5-phosphatase J; K01106 inositol-1,4,5-trisphosphate 5-phosphatase [EC:3.1.3.56] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endonuclease/Exonuclease/phosphatase family	"Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A GN=INPP5J OS=Homo sapiens (Human) PE=2 SV=3"	I	Lipid transport and metabolism	"PREDICTED: phosphatidylinositol 4,5-bisphosphate 5-phosphatase A isoform X1 [Panthera tigris altaica]"
ENSG00000185149(NPY2R)	--	0.196718746	11	0.304878	17	0.145942429	7	0.14188005	8	0.351544	19	0.091187709	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04205|0|ptr:461562|NPY2R; neuropeptide Y receptor Y2; K04205 neuropeptide Y receptor type 2 (A)	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuropeptide Y receptor type 2 GN=NPY2R OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neuropeptide Y receptor type 2 [Chrysochloris asiatica]
ENSG00000185155(MIXL1)	--	0.13583608	4	0	0	0.165547799	4	0.03365917	1	0.032760201	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	Homeobox domain	Homeobox protein MIXL1 GN=MIXL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: homeobox protein MIXL1, partial [Balaenoptera acutorostrata scammoni]"
ENSG00000185158(LRRC37B)	--	9.09767385	239	12.418588	310	11.38534842	270	7.696061427	221	12.0599372	304	11.76111945	321	0.958062465	-0.142841216	normal	0.965927625	-0.049380185	normal	0.9325281	0.240087725	normal	0.963418202	0.02666687	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	LRRC37A/B like protein 1 C-terminal domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 37B (Precursor) GN=LRRC37B OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: titin-like [Mustela putorius furo]
ENSG00000185163(DDX51)	--	6.68944	723	7.02623	777	6.8387	756	8.54859	922	10.0992	1087	7.20495	781	0.875557552	0.319336693	normal	0.51339644	0.462175113	normal	0.975958596	0.038568962	normal	0.185967221	0.284975426	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K14807|0|hsa:317781|DDX51; DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 (EC:3.6.4.13); K14807 ATP-dependent RNA helicase DDX51/DBP6 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	ATP-dependent RNA helicase DDX51 GN=DDX51 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX51 [Galeopterus variegatus]
ENSG00000185164(NOMO2)	--	15.329555	1293	12.86215927	1078	15.62673361	1335	14.527286	1224	12.798339	1073	13.4770299	1137	0.977680731	-0.109816832	normal	0.97965958	-0.028094156	normal	0.94859371	-0.239604484	normal	0.542395782	-0.131183283	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Carboxypeptidase regulatory-like domain;; Domain of unknown function (DUF4480);; Protein of unknown function (DUF2012);; Cna protein B-type domain;; Polysaccharide lyase family 4, domain II;; Protein of unknown function (DUF1416);; Y_Y_Y domain"	Nodal modulator 2 (Precursor) GN=NOMO2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nodal modulator 1 [Galeopterus variegatus]
ENSG00000185187(SIGIRR)	--	35.87186652	322	30.74395021	314	31.24380717	311	31.63323538	311	41.10674474	400	31.464679	312	0.96517996	-0.080587066	normal	0.870962746	0.326413088	normal	0.968071387	-0.003642311	normal	0.800513651	0.090289002	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K05169|0|hsa:59307|SIGIRR, TIR8; single immunoglobulin and toll-interleukin 1 receptor (TIR) domain; K05169 single Ig IL-1R-related molecule (A)"	--	--	--	TIR domain;; TIR domain	Single Ig IL-1-related receptor GN=SIGIRR OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: single Ig IL-1-related receptor isoform X1 [Sus scrofa] 
ENSG00000185189(NRBP2)	--	12.37024579	905	12.44755462	887	10.83717582	786	10.46643915	760	10.63198438	754	7.792563525	570	0.912873178	-0.282226962	normal	0.931520672	-0.255323387	normal	0.473803243	-0.470790427	normal	0.069596434	-0.329078389	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08875|0|ptr:746918|NRBP2; nuclear receptor binding protein 2; K08875 nuclear receptor-binding protein (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Nuclear receptor-binding protein 2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: nuclear receptor-binding protein 2 [Leptonychotes weddellii]
ENSG00000185198(PRSS57)	--	0.067641014	1	0	0	0	0	0.200568145	3	0.060431494	0	0.133258559	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin	Serine protease 57 (Precursor) GN=PRSS57 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine protease 57 [Vicugna pacos]
ENSG00000185201(IFITM2)	--	30.0288311	265	24.48425607	244	19.78901556	201	56.31873401	483	61.44921684	542	56.88238263	471	0.001625374	0.831577771	normal	7.15E-07	1.125186654	up	8.45E-08	1.214095181	up	2.59E-08	1.053640144	up	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06566|2.6518e-85|hsa:10581|IFITM2, 1-8D, DSPA2c; interferon induced transmembrane protein 2; K06566 interferon induced transmembrane protein (A)"	--	--	--	Interferon-induced transmembrane protein	Interferon-induced transmembrane protein 2 GN=IFITM2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: interferon-induced transmembrane protein 3-like [Ceratotherium simum simum]
ENSG00000185215(TNFAIP2)	--	164.5366416	12762	188.3537431	15214	153.8690494	12514	224.4452327	17332	253.1639965	19824	353.0765399	27720	0.911469306	0.410708868	normal	0.965080183	0.360390561	normal	7.93E-10	1.138997903	up	0.068949268	0.660105991	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: exocytosis (GO:0006887);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec6	Tumor necrosis factor alpha-induced protein 2 GN=TNFAIP2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: tumor necrosis factor alpha-induced protein 2 [Lipotes vexillifer]
ENSG00000185219(ZNF445)	--	2.589770808	514	2.506308352	533	2.763442509	543	2.414475079	468	2.752888268	521	2.751748633	578	0.956713264	-0.165573143	normal	0.970306338	-0.05412339	normal	0.969997816	0.081605536	normal	0.901973769	-0.041506408	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:353274|ZNF445, ZKSCAN15, ZNF168, ZSCAN47; zinc finger protein 445; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box"	Zinc finger protein 445 GN=ZNF445 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 445 [Leptonychotes weddellii]
ENSG00000185220(PGBD2)	--	2.96174129	137	2.757809	129	2.722067424	127	2.078267565	109	3.213158277	156	2.599240806	127	0.910878235	-0.356190366	normal	0.941540495	0.250079169	normal	0.968820906	-0.008193872	normal	0.975756335	-0.024363832	normal	--	--	--	--	--	--	--	Transposase IS4	PiggyBac transposable element-derived protein 2 GN=PGBD2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: piggyBac transposable element-derived protein 2 [Trichechus manatus latirostris]
ENSG00000185222(TCEAL9)	--	59.5723	1032	64.3105	1121	66.4833	1143	58.7769	1033	56.0326	959	60.7801	1043	0.97960392	-0.029391244	normal	0.941632652	-0.246250519	normal	0.972325577	-0.140183449	normal	0.51567718	-0.140121635	normal	--	--	--	--	--	--	--	Brain expressed X-linked like family	WW domain-binding protein 5 GN=WBP5 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: WW domain-binding protein 5 [Oryctolagus cuniculus]
ENSG00000185236(RAB11B)	--	56.13561881	1736	53.41887255	1677	55.4841195	1782	35.88707434	1121	38.03038296	1162	43.566558	1385	0.014116439	-0.661078469	normal	0.174514065	-0.550099632	normal	0.815035601	-0.371544158	normal	0.000334408	-0.522606922	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07905|5.81333e-161|ssc:100513782|RAB11B; RAB11B, member RAS oncogene family; K07905 Ras-related protein Rab-11B (A)"	Endocytosis (ko04144);; AMPK signaling pathway (ko04152);; Vasopressin-regulated water reabsorption (ko04962)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; 50S ribosome-binding GTPase;; AAA domain;; Elongation factor Tu GTP binding domain	Ras-related protein Rab-11B (Precursor) GN=RAB11B OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	"Ras-related protein Rab-11B, partial [Bos mutus]"
ENSG00000185238(PRMT3)	--	19.8634	856	18.02297789	801	16.98985384	746	18.86052	833	15.75889644	700	14.039208	618	0.975578955	-0.069999191	normal	0.947917933	-0.215438382	normal	0.911863499	-0.279237331	normal	0.401697551	-0.182117829	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	K11436|0|pps:100995732|PRMT3; protein arginine methyltransferase 3; K11436 protein arginine N-methyltransferase 3 [EC:2.1.1.-] (A)	--	[OKT]	"Posttranslational modification, protein turnover, chaperones;; Transcription;; Signal transduction mechanisms"	Ribosomal protein L11 methyltransferase (PrmA);; Methyltransferase domain;; Methyltransferase domain;; Protein of unknown function (DUF1698);; Methyltransferase domain;; Methyltransferase domain;; PRMT5 arginine-N-methyltransferase;; Methyltransferase domain;; Methyltransferase small domain;; Methyltransferase domain;; Met-10+ like-protein	Protein arginine N-methyltransferase 3 GN=PRMT3 OS=Homo sapiens (Human) PE=1 SV=3	KOT	"Transcription;; Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: protein arginine N-methyltransferase 3 isoform X1 [Lipotes vexillifer]
ENSG00000185245(GP1BA)	--	2.705739	124	1.957338	89	2.43777	109	2.10126	94	2.526012	114	2.480249	113	0.880916689	-0.424378709	normal	0.931188594	0.33075345	normal	0.969436674	0.043115663	normal	0.97799303	-0.024970542	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06261|0|hsa:2811|GP1BA, BDPLT1, BDPLT3, BSS, CD42B, CD42b-alpha, DBPLT3, GP1B, GPIbA, VWDP; glycoprotein Ib (platelet), alpha polypeptide; K06261 platelet glycoprotein Ib alpha chain (A)"	ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Hematopoietic cell lineage (ko04640)	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Glycocalicin (Precursor) GN=GP1BA OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: platelet glycoprotein Ib alpha chain [Galeopterus variegatus]
ENSG00000185246(PRPF39)	--	8.902583994	448	8.963739154	449	9.187413808	451	8.181948393	414	9.072496069	454	10.042187	504	0.959657702	-0.144185633	normal	0.9700081	-0.005431513	normal	0.959424906	0.151524007	normal	0.996314771	0.004880648	normal	[R]	General function prediction only	--	K13217|0|hsa:55015|PRPF39; pre-mRNA processing factor 39; K13217 pre-mRNA-processing factor 39 (A)	--	[A]	RNA processing and modification	Tetratricopeptide repeat;; Tetratricopeptide repeat;; Suppressor of forked protein (Suf)	Pre-mRNA-processing factor 39 GN=PRPF39 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: pre-mRNA-processing factor 39 isoform X1 [Oryctolagus cuniculus] 
ENSG00000185250(PPIL6)	--	1.357166384	56	0.626819153	27	0.593044609	19	0.906941634	38	0.8662766	30	0.880424086	33	0.916131269	-0.571114113	normal	0.983770898	0.123986492	normal	0.937781792	0.742817566	normal	0.987369772	-0.036938557	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K12739|0|hsa:285755|PPIL6, PPIase, RSPH12, bA425D10.6, dJ919F19.1; peptidylprolyl isomerase (cyclophilin)-like 6 (EC:5.2.1.8); K12739 peptidyl-prolyl cis-trans isomerase-like 6 [EC:5.2.1.8] (A)"	--	--	--	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase-like 6 GN=PPIL6 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase-like 6 isoform 1 [Dasypus novemcinctus]
ENSG00000185252(ZNF74)	--	3.923608	236	4.150007104	217	3.620646701	244	3.67516293	235	4.368530702	285	4.47128231	289	0.966506092	-0.036718807	normal	0.840510771	0.369586733	normal	0.935661049	0.234559628	normal	0.557907426	0.19460261	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101145707|ZNF74; zinc finger protein 74 isoform 1; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 74 GN=ZNF74 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 74 isoform X2 [Galeopterus variegatus]
ENSG00000185261(KIAA0825)	--	0.901179927	27	0.441490922	14	0.350002749	14	0.7581932	27	0.79419831	32	0.8641483	32	0.986256965	-0.029172236	normal	0.798924144	1.091380185	normal	0.794971665	1.103578511	normal	0.312307405	0.705309344	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4495)	Uncharacterized protein KIAA0825 GN=KIAA0825 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA0825 homolog [Tupaia chinensis]
ENSG00000185262(UBALD2)	--	27.77069481	636	25.77307358	608	23.53366916	625	31.72105757	737	26.21933611	578	38.79912849	962	0.9570921	0.181398249	normal	0.968852677	-0.094188074	normal	0.056686793	0.612685331	normal	0.502259382	0.264428779	normal	--	--	--	--	--	--	--	UBA-like domain	UBA-like domain-containing protein 2 GN=UBALD2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UBA-like domain-containing protein 2 isoform X2 [Bos taurus] 
ENSG00000185267(CDNF)	--	1.11677	26	0.3759515	6	1.077498	21	0.594162	14	0.833243	19	0.370998	7	0.944781233	-0.854132613	normal	--	--	--	0.830667018	-1.410370345	normal	--	--	--	--	--	--	--	--	[R]	General function prediction only	Degradation arginine-rich protein for mis-folding	Cerebral dopamine neurotrophic factor (Precursor) GN=CDNF OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: cerebral dopamine neurotrophic factor [Tupaia chinensis]
ENSG00000185269(NOTUM)	--	0.312222074	12	0.125885183	5	0.342632593	12	0	0	0.207244163	8	0.210828483	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	Pectinacetylesterase	Protein notum homolog (Precursor) GN=NOTUM OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: protein notum homolog [Odobenus rosmarus divergens]
ENSG00000185271(KLHL33)	--	0.030352125	1	0	0	0	0	0.045681535	4	0.011197418	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K13957|0|ptr:465199|KLHL33; kelch-like family member 33; K13957 kelch-like protein 33 (A)	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; BTB And C-terminal Kelch;; Kelch motif"	Kelch-like protein 33 GN=KLHL33 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: kelch-like protein 33 isoform X1 [Galeopterus variegatus]
ENSG00000185272(RBM11)	--	0.262119	7	0.1136	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing regulator RBM11 GN=RBM11 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: splicing regulator RBM11 [Camelus dromedarius]
ENSG00000185278(ZBTB37)	--	1.473543818	447	1.800784003	541	1.773353658	524	1.488413836	334	1.39305163	366	1.584574918	401	0.615844022	-0.449464567	normal	0.163621151	-0.583215935	normal	0.75275075	-0.392955608	normal	0.017072638	-0.478205179	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10509|0|ptr:457527|ZBTB37; zinc finger and BTB domain containing 37; K10509 zinc finger and BTB domain-containing protein 37 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger and BTB domain-containing protein 37 GN=ZBTB37 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 37 isoform 1 [Dasypus novemcinctus] 
ENSG00000185291(IL3RA)	--	0.532784671	9	0.472715292	12	0.368269833	7	0.236830565	6	0.231592934	5	0.392146917	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Interleukin-6 receptor alpha chain, binding"	Interleukin-3 receptor subunit alpha (Precursor) GN=IL3RA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-3 receptor subunit alpha [Galeopterus variegatus]
ENSG00000185298(CCDC137)	--	26.59669789	1501	21.78780599	1304	25.53229531	1537	31.1983894	1765	34.79943998	1979	26.72390208	1547	0.966954668	0.202720432	normal	0.103272378	0.579851647	normal	0.984362956	0.001063547	normal	0.132961846	0.263904451	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 137 GN=CCDC137 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 137 [Equus przewalskii]
ENSG00000185303(SFTPA2)	--	0	0	0	0	0	0	0.023603288	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10067|3.68539e-130|hsa:729238|SFTPA2, COLEC5, PSAP, PSP-A, PSPA, SFTP1, SFTPA2B, SP-A, SPA2, SPAII; surfactant protein A2; K10067 pulmonary surfactant-associated protein A (A)"	Phagosome (ko04145);; Pertussis (ko05133)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; Collagen triple helix repeat (20 copies)	Pulmonary surfactant-associated protein A2 (Precursor) GN=SFTPA2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: pulmonary surfactant-associated protein A1 isoform 2 [Ceratotherium simum simum]
ENSG00000185304(RGPD2)	--	0	0	0.050132	7	0.0215116	2	0.01429	2	0.0208799	2	0.0214018	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:729857|RGPD2, NUP358, RANBP2L2, RGP2; RANBP2-like and GRIP domain containing 2; K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; GRIP domain;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RANBP2-like and GRIP domain-containing protein 2 GN=RGPD2 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ceratotherium simum simum]
ENSG00000185305(ARL15)	--	5.270606071	203	5.563940135	203	4.092644532	179	5.047006316	221	8.3687873	288	10.06166889	245	0.963706221	0.091073651	normal	0.630979948	0.480145672	normal	0.750641072	0.441331236	normal	0.242803283	0.345123719	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K17201|3.09764e-150|hsa:54622|ARL15, ARFRP2; ADP-ribosylation factor-like 15; K17201 ADP-ribosylation factor-like protein 15 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Miro-like protein;; Ras family;; Gtr1/RagA G protein conserved region	ADP-ribosylation factor-like protein 15 GN=ARL15 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 15 [Ceratotherium simum simum]
ENSG00000185306(C12orf56)	--	0.05467949	4	0.109848381	6	0.073579701	4	0.459295838	10	0.164031126	2	0.03590012	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF4551)	Uncharacterized protein C12orf56 GN=C12orf56 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C12orf56 homolog [Vicugna pacos]
ENSG00000185324(CDK10)	--	11.9978297	486	10.96025	455	11.4600914	474	11.0406963	435	12.5657863	482	13.437408	553	0.950015458	-0.190137376	normal	0.968668392	0.0615413	normal	0.94374711	0.213469857	normal	0.926977546	0.034580059	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02449|0|pps:100979052|CDK10; cyclin-dependent kinase 10; K02449 cyclin-dependent kinase 10 [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Cyclin-dependent kinase 10 GN=CDK10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cyclin-dependent kinase 10 [Orycteropus afer afer]
ENSG00000185332(TMEM105)	--	0.594654153	41	0.431184917	27	0.749036095	26	1.242088861	20	0.742758411	32	1.217339859	29	0.720743719	-1.011094136	normal	0.981706811	0.212731494	normal	0.984838306	0.141456156	normal	0.795087535	-0.23513022	normal	--	--	--	--	--	--	--	--	Transmembrane protein 105 GN=TMEM105 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC102336561 [Pantholops hodgsonii]
ENSG00000185338(SOCS1)	--	1.04212	14	0.432071	6	0.554134	7	0.437586	6	0.566933	7	0.653833	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	K04694|4.06979e-118|cjc:100402275|SOCS1; suppressor of cytokine signaling 1; K04694 suppressor of cytokine signaling 1 (A)	Ubiquitin mediated proteolysis (ko04120);; Osteoclast differentiation (ko04380);; Jak-STAT signaling pathway (ko04630);; Insulin signaling pathway (ko04910);; Prolactin signaling pathway (ko04917);; Type II diabetes mellitus (ko04930);; Toxoplasmosis (ko05145);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	SH2 domain;; SOCS box	Suppressor of cytokine signaling 1 GN=SOCS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: suppressor of cytokine signaling 1 [Mustela putorius furo] 
ENSG00000185339(TCN2)	--	3.320728	150	2.900549812	130	3.695779	170	5.636458	237	4.648647	207	4.970993	236	0.281404985	0.623968118	normal	0.295481455	0.643709129	normal	0.719317654	0.461461721	normal	0.041865243	0.574732878	normal	--	--	Biological Process: cobalamin transport (GO:0015889);; Molecular Function: cobalamin binding (GO:0031419);; 	"K14619|0|hsa:6948|TCN2, D22S676, D22S750, II, TC, TC_II, TC-2, TC2, TCII; transcobalamin II; K14619 transcobalamin-2 (A)"	Vitamin digestion and absorption (ko04977)	--	--	Eukaryotic cobalamin-binding protein;; Domain of unknown function (DUF4430)	Transcobalamin-2 (Precursor) GN=TCN2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: transcobalamin-2 isoform X1 [Tupaia chinensis] 
ENSG00000185340(GAS2L1)	--	20.1540514	824	13.802752	701	16.36802119	742	9.95521666	498	10.299206	469	9.80514004	458	0.002647632	-0.755498087	normal	0.101254363	-0.59966012	normal	0.01103258	-0.702522509	normal	3.15E-05	-0.691288189	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: microtubule binding (GO:0008017);; 	--	--	[Z]	Cytoskeleton	Growth-Arrest-Specific Protein 2 Domain;; Calponin homology (CH) domain	GAS2-like protein 1 GN=GAS2L1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: GAS2-like protein 1 [Galeopterus variegatus]
ENSG00000185344(ATP6V0A2)	--	7.242994374	669	7.014464925	662	7.257946326	664	8.482026126	772	9.157089	850	8.071278214	769	0.959287339	0.175387188	normal	0.851502735	0.33852105	normal	0.95170971	0.203078776	normal	0.231534709	0.240077131	normal	[C]	Energy production and conversion	"Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V0 domain (GO:0033179);; "	"K02154|0|hsa:23545|ATP6V0A2, A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS; ATPase, H+ transporting, lysosomal V0 subunit a2 (EC:3.6.3.6); K02154 V-type H+-transporting ATPase subunit a (A)"	Oxidative phosphorylation (ko00190);; Lysosome (ko04142);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Tuberculosis (ko05152);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	V-type ATPase 116kDa subunit family	V-type proton ATPase 116 kDa subunit a isoform 2 GN=ATP6V0A2 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: V-type proton ATPase 116 kDa subunit a isoform 2 [Galeopterus variegatus]
ENSG00000185345(PARK2)	--	18.71936881	22	0.013945335	1	0.068990276	4	0.023282107	1	0.21522677	4	0.041427167	3	0.006949805	-3.234516602	down	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K04556|0|hsa:5071|PARK2, AR-JP, LPRS2, PDJ, PRKN; parkin RBR E3 ubiquitin protein ligase; K04556 parkin [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin family;; IBR domain;; Ubiquitin-2 like Rad60 SUMO-like	E3 ubiquitin-protein ligase parkin GN=PARK2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase parkin-like isoform X1 [Tupaia chinensis]
ENSG00000185347(C14orf80)	--	24.95742206	629	20.84821038	586	27.07216266	683	19.37209169	511	20.49007343	525	18.76567107	474	0.85815699	-0.329673635	normal	0.954311641	-0.179520035	normal	0.254330227	-0.533862915	normal	0.073531733	-0.351080651	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4510);; Domain of unknown function (DUF4509)	Uncharacterized protein C14orf80 GN=C14orf80 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C14orf80 homolog isoform 1 [Ceratotherium simum simum]
ENSG00000185352(HS6ST3)	--	0.015859071	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08103|0|hsa:266722|HS6ST3, HS6ST-3; heparan sulfate 6-O-sulfotransferase 3 (EC:2.8.2.-); K08103 heparan sulfate 6-O-sulfotransferase HS6ST3 [EC:2.8.2.-] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[MG]	Cell wall/membrane/envelope biogenesis;; Carbohydrate transport and metabolism	Sulfotransferase family	Heparan-sulfate 6-O-sulfotransferase 3 GN=HS6ST3 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan-sulfate 6-O-sulfotransferase 3 [Tupaia chinensis]
ENSG00000185359(HGS)	--	40.22468097	2157	38.519668	2002	38.128022	2340	54.51532163	3184	54.20305906	2920	46.17824602	2633	0.240835476	0.530669029	normal	0.294420066	0.522771073	normal	0.98109672	0.161808915	normal	0.007230474	0.405389667	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: metal ion binding (GO:0046872);; 	"K12182|0|hsa:9146|HGS, HRS; hepatocyte growth factor-regulated tyrosine kinase substrate; K12182 hepatocyte growth factor-regulated tyrosine kinase substrate (A)"	Endocytosis (ko04144);; Phagosome (ko04145)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	VHS domain;; Hepatocyte growth factor-regulated tyrosine kinase substrate;; FYVE zinc finger	Hepatocyte growth factor-regulated tyrosine kinase substrate GN=HGS OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: hepatocyte growth factor-regulated tyrosine kinase substrate [Tursiops truncatus]
ENSG00000185361(TNFAIP8L1)	--	6.147820101	481	3.49910264	279	4.994735999	396	4.023369732	315	2.946790238	229	2.543181645	199	0.07125892	-0.63897459	normal	0.899893967	-0.304518827	normal	7.31E-05	-0.995553207	normal	0.124249222	-0.660195659	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF758)	Tumor necrosis factor alpha-induced protein 8-like protein 1 GN=TNFAIP8L1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor alpha-induced protein 8-like protein 1 [Condylura cristata]
ENSG00000185372(OR2V1)	--	0.1024	1	0.102205	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:26693|OR2V1, OR2V1P, OST265; olfactory receptor, family 2, subfamily V, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 2V1 GN=OR2V1 OS=Homo sapiens (Human) PE=3 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 56-like [Condylura cristata]
ENSG00000185386(MAPK11)	--	9.304726579	411	8.134635	365	8.099453	371	3.917914324	191	3.818764	175	4.999881	221	1.84E-06	-1.130041715	down	2.00E-05	-1.075383509	down	0.016736577	-0.751649441	normal	2.00E-06	-0.987282297	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K04441|0|hsa:5600|MAPK11, P38B, P38BETA2, PRKM11, SAPK2, SAPK2B, p38-2, p38Beta; mitogen-activated protein kinase 11 (EC:2.7.11.24); K04441 p38 MAP kinase [EC:2.7.11.24] (A)"	MAPK signaling pathway (ko04010);; Rap1 signaling pathway (ko04015);; FoxO signaling pathway (ko04068);; Sphingolipid signaling pathway (ko04071);; Adrenergic signaling in cardiomyocytes (ko04261);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Platelet activation (ko04611);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; TNF signaling pathway (ko04668);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Retrograde endocannabinoid signaling (ko04723);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Progesterone-mediated oocyte maturation (ko04914);; Prolactin signaling pathway (ko04917);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Shigellosis (ko05131);; Salmonella infection (ko05132);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Lipopolysaccharide kinase (Kdo/WaaP) family;; Phosphotransferase enzyme family	Mitogen-activated protein kinase 11 GN=MAPK11 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase 11 [Oryctolagus cuniculus]
ENSG00000185404(SP140L)	--	3.407152895	231	3.887703607	268	3.955601662	275	3.025962772	227	3.352795473	249	3.48542203	286	0.965779604	-0.055659354	normal	0.958945315	-0.126771452	normal	0.966605138	0.04803306	normal	0.923805752	-0.042885465	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Sp100 domain;; SAND domain;; Bromodomain;; PHD-finger	Nuclear body protein SP140-like protein GN=SP140L OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: nuclear body protein SP140-like protein-like [Ceratotherium simum simum]
ENSG00000185418(TARSL2)	--	3.678621819	260	2.658585979	176	2.567578664	180	5.201983053	297	4.919465926	322	2.50110347	177	0.954946499	0.160232682	normal	0.005353979	0.844616399	normal	0.96683395	-0.032265613	normal	0.517734466	0.347185224	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; Molecular Function: ligase activity, forming aminoacyl-tRNA and related compounds (GO:0016876);; Biological Process: tRNA aminoacylation (GO:0043039);; "	K01868|0|hsa:123283|TARSL2; threonyl-tRNA synthetase-like 2 (EC:6.1.1.3); K01868 threonyl-tRNA synthetase [EC:6.1.1.3] (A)	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetase class II core domain (G, H, P, S and T);; Anticodon binding domain;; TGS domain;; Threonyl and Alanyl tRNA synthetase second additional domain"	"Probable threonine--tRNA ligase 2, cytoplasmic GN=TARSL2 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: probable threonine--tRNA ligase 2, cytoplasmic isoform 1 [Ceratotherium simum simum]"
ENSG00000185420(SMYD3)	--	13.09234296	329	10.17695867	248	11.12521197	272	11.92736071	296	13.04028842	335	9.836864	247	0.950310337	-0.182423941	normal	0.76265265	0.410234836	normal	0.957367173	-0.146531752	normal	0.956592571	0.026823905	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11426|0|hsa:64754|SMYD3, KMT3E, ZMYND1, ZNFN3A1, bA74P14.1; SET and MYND domain containing 3 (EC:2.1.1.43); K11426 SET and MYND domain-containing protein (A)"	--	[B]	Chromatin structure and dynamics	SET domain;; MYND finger	Histone-lysine N-methyltransferase SMYD3 GN=SMYD3 OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase SMYD3 [Oryctolagus cuniculus]
ENSG00000185432(METTL7A)	--	0.119345143	5	0.186298942	10	0.1290834	7	0.074844549	4	0.201252908	10	0.223117	13	--	--	--	--	--	--	--	--	--	--	--	--	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Cellular Component: nucleolus (GO:0005730);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: S-adenosylmethionine-dependent methyltransferase activity (GO:0008757);; Biological Process: oligosaccharide biosynthetic process (GO:0009312);; Biological Process: nodulation (GO:0009877);; 	--	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; Hypothetical methyltransferase;; Nodulation protein S (NodS)	Methyltransferase-like protein 7A (Precursor) GN=METTL7A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: methyltransferase-like protein 7A [Sorex araneus]
ENSG00000185436(IFNLR1)	--	1.227042794	99	0.887508556	81	0.850233625	79	0.948587652	87	0.772566029	71	0.998472539	78	0.960686881	-0.213704314	normal	0.963961446	-0.207390268	normal	0.973265823	-0.026165875	normal	0.804117513	-0.155956447	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05140|0|hsa:163702|IFNLR1, CRF2/12, IFNLR, IL-28R1, IL28RA, LICR2; interferon, lambda receptor 1; K05140 interleukin 28 receptor alpha (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	Tissue factor	Interferon lambda receptor 1 (Precursor) GN=IFNLR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interferon lambda receptor 1 [Physeter catodon]
ENSG00000185437(SH3BGR)	--	0.698099443	10	1.704307	22	1.063779895	14	0.958041441	17	1.324244246	25	1.28589605	25	--	--	--	0.985707881	0.153119849	normal	0.960277819	0.765598898	normal	0.541194532	0.522128206	normal	--	--	--	--	--	[S]	Function unknown	"SH3-binding, glutamic acid-rich protein"	SH3 domain-binding glutamic acid-rich protein GN=SH3BGR OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: SH3 domain-binding glutamic acid-rich protein [Camelus bactrianus]
ENSG00000185442(FAM174B)	--	1.325588953	59	1.478999246	66	1.197442392	54	3.167705933	143	4.486701725	157	3.732016348	149	0.000569353	1.225279888	up	0.000385509	1.210288281	up	1.39E-05	1.430865359	up	5.45E-05	1.305450811	up	--	--	--	--	--	--	--	Protein of unknown function (DUF1180)	Membrane protein FAM174B (Precursor) GN=FAM174B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: membrane protein FAM174B isoform X1 [Sus scrofa]
ENSG00000185453(C19orf68)	--	7.195477	575	6.175005	525	5.97050734	541	7.249989872	614	8.088995	647	6.351083	520	0.971752214	0.063679764	normal	0.910220318	0.279295903	normal	0.97053812	-0.065222433	normal	0.729684355	0.09650065	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C19orf68 GN=C19orf68 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C19orf68 homolog [Galeopterus variegatus]
ENSG00000185467(KPNA7)	--	0.0622503	2	0.0308906	1	0	0	0.713385	23	0.545757	17	0.338945	11	0.027292643	2.771388193	normal	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein import into nucleus (GO:0006606);; Molecular Function: protein transporter activity (GO:0008565);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Armadillo/beta-catenin-like repeat;; HEAT repeats;; HEAT-like repeat;; HEAT repeat;; Importin beta binding domain;; Adaptin N terminal region;; Armadillo-like;; PBS lyase HEAT-like repeat	Importin subunit alpha-8 GN=KPNA7 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin subunit alpha-8 [Galeopterus variegatus]
ENSG00000185477(GPRIN3)	--	8.92122773	2146	9.39918836	2287	10.03143016	2153	6.849526562	1631	8.322929441	1918	10.19509097	2367	0.666771462	-0.426374134	normal	0.946145766	-0.27508128	normal	0.983340086	0.128333945	normal	0.495752115	-0.17491075	normal	--	--	--	--	--	--	--	G protein-regulated inducer of neurite outgrowth C-terminus	G protein-regulated inducer of neurite outgrowth 3 GN=GPRIN3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: G protein-regulated inducer of neurite outgrowth 3 [Galeopterus variegatus]
ENSG00000185479(KRT6B)	--	0	0	0.0201644	1	0.0198245	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|ptr:738608|KRT6A, KRT6B, KRT6C; keratin, type II cytoskeletal 6B; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein;; TPR/MLP1/MLP2-like protein	"Keratin, type II cytoskeletal 6B GN=KRT6B OS=Homo sapiens (Human) PE=1 SV=5"	Z	Cytoskeleton	"PREDICTED: keratin, type II cytoskeletal 6A [Galeopterus variegatus]"
ENSG00000185480(PARPBP)	--	14.408325	554	14.1007481	584	16.8988333	651	15.14913401	572	13.24516464	522	12.9280176	526	0.972861927	0.015255271	normal	0.953409792	-0.182843987	normal	0.876691441	-0.315070318	normal	0.504738712	-0.164393798	normal	--	--	--	--	--	--	--	--	PCNA-interacting partner GN=PARPBP OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: PCNA-interacting partner [Balaenoptera acutorostrata scammoni]
ENSG00000185482(STAC3)	--	0.365451689	13	0.655399059	19	0.13607666	5	0.299804102	12	0.335630417	12	0.465543538	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	--	--	Variant SH3 domain;; Variant SH3 domain;; SH3 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	SH3 and cysteine-rich domain-containing protein 3 GN=STAC3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SH3 and cysteine-rich domain-containing protein 3 [Panthera tigris altaica] 
ENSG00000185483(ROR1)	--	3.114096166	300	2.777801975	236	2.8701715	272	6.256217787	599	4.887397	478	4.205964471	394	3.06E-05	0.963205065	normal	4.62E-05	0.992241067	normal	0.400090519	0.523864199	normal	0.002431389	0.84196511	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05122|0|ptr:456910|ROR1; receptor tyrosine kinase-like orphan receptor 1; K05122 receptor tyrosine kinase-like orphan receptor 1 [EC:2.7.10.1] (A)	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Protein tyrosine kinase;; Protein kinase domain;; Fz domain;; Kringle domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Tyrosine-protein kinase transmembrane receptor ROR1 (Precursor) GN=ROR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase transmembrane receptor ROR1 [Orycteropus afer afer]
ENSG00000185499(MUC1)	--	3.669302059	149	3.7636676	114	4.9885108	149	6.457676631	193	4.645526382	144	5.957339233	225	0.897640061	0.339374413	normal	0.925488291	0.311919692	normal	0.420768592	0.581485931	normal	0.208855259	0.427371996	normal	--	--	--	"K06568|0|pon:100445764|MUC1; mucin 1, cell surface associated; K06568 mucin 1, transmembrane (A)"	--	--	--	SEA domain	Mucin-1 subunit beta (Precursor) GN=MUC1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	Muc1 [Oryctolagus cuniculus]
ENSG00000185504(FAAP100)	--	11.98459399	751	11.04261166	694	12.09731719	738	17.22910449	934	14.76434442	883	13.81618344	879	0.912323244	0.28325692	normal	0.870029707	0.325421234	normal	0.937384955	0.243493174	normal	0.128600175	0.283178327	normal	--	--	Biological Process: DNA repair (GO:0006281);; Cellular Component: Fanconi anaemia nuclear complex (GO:0043240);; 	"K10993|0|hsa:80233|C17orf70, FAAP100; chromosome 17 open reading frame 70; K10993 fanconi anemia core complex 100 kDa subunit (A)"	Fanconi anemia pathway (ko03460)	--	--	Fanconi anemia-associated	Fanconi anemia-associated protein of 100 kDa GN=FAAP100 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: Fanconi anemia-associated protein of 100 kDa [Equus przewalskii]
ENSG00000185507(IRF7)	--	1.176959137	42	1.2889107	47	0.735319715	26	1.478317622	50	1.900050889	65	2.23964	78	0.975750035	0.213540634	normal	0.939239458	0.434421665	normal	0.001514357	1.523116995	up	0.151339643	0.726228617	normal	--	--	"Molecular Function: regulatory region DNA binding (GO:0000975);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09447|0|ptr:450927|IRF7; interferon regulatory factor 7; K09447 interferon regulatory factor 7 (A)	Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Viral carcinogenesis (ko05203)	--	--	Interferon-regulatory factor 3;; Interferon regulatory factor transcription factor	Interferon regulatory factor 7 GN=IRF7 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: interferon regulatory factor 7 isoform X1 [Galeopterus variegatus]
ENSG00000185513(L3MBTL1)	--	1.515034999	69	1.112518617	83	1.055628288	91	1.371421371	57	0.813938161	54	1.111992033	53	0.960926409	-0.299125446	normal	0.781139675	-0.627296968	normal	0.496281564	-0.771172189	normal	0.209768697	-0.588382603	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	--	--	[K]	Transcription	"mbt repeat;; Zinc finger, C2HC type"	Lethal(3)malignant brain tumor-like protein 1 GN=L3MBTL1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: lethal(3)malignant brain tumor-like protein 1 [Canis lupus familiaris]
ENSG00000185515(BRCC3)	--	17.7430028	1208	16.9426857	1191	19.413915	1261	20.75776446	1450	17.16083958	1244	17.08401853	1201	0.953133438	0.232330185	normal	0.980782223	0.041335158	normal	0.979779385	-0.078527056	normal	0.786144857	0.068070876	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11864|0|nle:100607439|BRCC3; BRCA1/BRCA2-containing complex, subunit 3; K11864 BRCA1/BRCA2-containing complex subunit 3 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	JAB1/Mov34/MPN/PAD-1 ubiquitin protease;; Prokaryotic homologs of the JAB domain	Lys-63-specific deubiquitinase BRCC36 GN=BRCC3 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: lys-63-specific deubiquitinase BRCC36 isoform 1 [Trichechus manatus latirostris]
ENSG00000185519(FAM131C)	--	10.57461	328	6.15553	192	9.69623	304	8.91485	275	9.01222	275	7.23676	226	0.909741602	-0.28364311	normal	0.607316538	0.493634166	normal	0.725436944	-0.433529303	normal	0.833261861	-0.107913367	normal	--	--	--	--	--	--	--	Putative cell signalling	Protein FAM131C GN=FAM131C OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM131C [Equus caballus]
ENSG00000185522(LMNTD2)	--	3.011345707	127	3.084514042	92	2.35320037	106	1.414414399	61	1.744328	76	2.2610423	99	0.009248904	-1.069677229	down	0.949511352	-0.291775203	normal	0.967976256	-0.105300425	normal	0.253230572	-0.481377497	normal	--	--	--	--	--	[DY]	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	Lamin Tail Domain	Lamin tail domain-containing protein 2 GN=LMNTD2 OS=Homo sapiens (Human) PE=2 SV=2	DY	"Cell cycle control, cell division, chromosome partitioning;; Nuclear structure"	PREDICTED: uncharacterized protein C11orf35 homolog [Odobenus rosmarus divergens]
ENSG00000185523(SPATA45)	--	0	0	0	0	0	0	0	0	0.212852	0	0.629883	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Spermatogenesis-associated protein 45 GN=SPATA45 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: UPF0732 protein C1orf227 homolog [Panthera tigris altaica]
ENSG00000185527(PDE6G)	--	1.2530477	20	1.252715131	21	1.546513848	18	0.495330971	6	0.492238883	6	1.423713184	18	0.791479127	-1.541412393	normal	0.703742064	-1.601939823	normal	--	--	--	--	--	--	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: visual perception (GO:0007601);; Molecular Function: cGMP binding (GO:0030553);; "	"K13759|2.66263e-94|pps:100968456|PDE6G; phosphodiesterase 6G, cGMP-specific, rod, gamma; K13759 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (A)"	Purine metabolism (ko00230);; Phototransduction (ko04744)	--	--	"Retinal cGMP phosphodiesterase, gamma subunit"	"Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma GN=PDE6G OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	hypothetical protein PANDA_000713 [Ailuropoda melanoleuca]
ENSG00000185532(PRKG1)	--	0.0827348	8	0.0104414	1	0.0314094	2	0.0308311	3	0	0	0.0718287	7	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07376|0|mcf:102122483|PRKG1; protein kinase, cGMP-dependent, type I; K07376 protein kinase, cGMP-dependent [EC:2.7.11.12] (A)"	cGMP-PKG signaling pathway (ko04022);; Gap junction (ko04540);; Platelet activation (ko04611);; Circadian entrainment (ko04713);; Long-term depression (ko04730);; Olfactory transduction (ko04740);; Salivary secretion (ko04970)	[T]	Signal transduction mechanisms	Protein kinase domain;; Cyclic nucleotide-binding domain;; Protein tyrosine kinase	cGMP-dependent protein kinase 1 GN=PRKG1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: cGMP-dependent protein kinase 1 isoform X1 [Elephantulus edwardii]
ENSG00000185551(NR2F2)	--	12.0448882	812	11.45596224	723	11.05328209	726	19.49790084	916	17.76772065	992	17.2501547	919	0.968350308	0.142781145	normal	0.620462562	0.434139762	normal	0.860556388	0.331189351	normal	0.096311119	0.30110164	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08548|0|rno:113984|Nr2f2, Tfcoup2; nuclear receptor subfamily 2, group F, member 2; K08548 COUP transcription factor 2 (A)"	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	COUP transcription factor 2 GN=NR2F2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	COUP transcription factor 2 isoform 1 [Sus scrofa] 
ENSG00000185559(DLK1)	--	0.01181714	1	0	0	0.0234639	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	EGF-like domain;; Human growth factor-like EGF;; EGF-like domain	Fetal antigen 1 (Precursor) GN=DLK1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein delta homolog 1 [Oryctolagus cuniculus]
ENSG00000185561(TLCD2)	--	2.55539023	340	1.882501213	255	2.145149336	287	3.345211552	446	3.07786825	406	2.905468042	386	0.824503926	0.359255615	normal	0.093734019	0.646491979	normal	0.726623156	0.41735576	normal	0.033625105	0.467516558	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TLC domain	TLC domain-containing protein 2 GN=TLCD2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: TLC domain-containing protein 2 [Camelus ferus] 
ENSG00000185565(LSAMP)	--	0.27164376	33	0.19815825	23	0.175288891	26	0.516665004	59	0.571523885	83	0.788934099	58	0.77207623	0.779928668	normal	6.69E-05	1.76508211	up	0.281832661	1.105153245	normal	0.006227337	1.265202523	up	--	--	--	K06772|0|ptr:460600|LSAMP; limbic system-associated membrane protein; K06772 limbic system-associated membrane protein (A)	--	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain;; CD47 immunoglobulin-like domain	Limbic system-associated membrane protein (Precursor) GN=LSAMP OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: limbic system-associated membrane protein isoform X1 [Oryctolagus cuniculus]
ENSG00000185567(AHNAK2)	--	74.11452	27013	95.2799474	33993	93.789822	33789	108.5894059	37941	87.9143	32198	111.5114	40161	0.88722751	0.459249436	normal	0.99823323	-0.099688613	normal	0.995649599	0.240940194	normal	0.418484891	0.197596827	normal	--	--	--	--	--	--	--	Family of unknown function (DUF490);; PDZ domain (Also known as DHR or GLGF)	Protein AHNAK2 GN=AHNAK2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: protein AHNAK2 [Ovis aries]
ENSG00000185585(OLFML2A)	--	16.00696608	2070	15.65166549	2041	14.43545973	1894	13.98280934	1798	14.90206736	1922	14.96353	1885	0.961313383	-0.233883545	normal	0.983090143	-0.108011915	normal	0.986300595	-0.015151123	normal	0.56968376	-0.120612068	normal	--	--	--	--	--	[W]	Extracellular structures	Olfactomedin-like domain	Olfactomedin-like protein 2A (Precursor) GN=OLFML2A OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: olfactomedin-like protein 2A [Equus caballus]
ENSG00000185591(SP1)	--	17.26691924	2205	17.59462665	2397	16.62973184	2248	18.06967898	2463	17.56131249	2350	17.95593295	2400	0.983658908	0.128720818	normal	0.987479516	-0.049963873	normal	0.986343534	0.086044898	normal	0.835100739	0.053154743	normal	[R]	General function prediction only	--	K04684|0|ptr:451939|SP1; Sp1 transcription factor; K04684 transcription factor Sp1 (A)	TGF-beta signaling pathway (ko04350);; Estrogen signaling pathway (ko04915);; Huntington's disease (ko05016);; Transcriptional misregulation in cancer (ko05202);; Choline metabolism in cancer (ko05231)	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Transcription factor Sp1 GN=SP1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcription factor Sp1 isoform 1 [Ceratotherium simum simum]
ENSG00000185608(MRPL40)	--	18.87473	399	14.73128	312	15.94797	342	17.20071	367	15.10873	319	16.17751	337	0.957624237	-0.150835072	normal	0.967099707	0.010533346	normal	0.968214181	-0.029408173	normal	0.868753358	-0.063217682	normal	--	--	--	"K17421|5.68091e-111|hsa:64976|MRPL40, MRP-L22, MRPL22, NLVCF, URIM; mitochondrial ribosomal protein L40; K17421 large subunit ribosomal protein L40 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Mitochondrial ribosomal protein L28	"39S ribosomal protein L40, mitochondrial (Precursor) GN=MRPL40 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L40, mitochondrial [Loxodonta africana]"
ENSG00000185614(FAM212A)	--	0.386607	7	0.210834	4	0.566766	10	0.592237	11	0.107714	1	0.216273	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM212 family	Protein FAM212A GN=FAM212A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM212A [Galeopterus variegatus]
ENSG00000185615(PDIA2)	--	0.10778854	3	0.510115118	3	0.329820051	1	0.037471313	1	0.168416049	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	"K09581|0|hsa:64714|PDIA2, PDA2, PDI, PDIP, PDIR; protein disulfide isomerase family A, member 2 (EC:5.3.4.1); K09581 protein disulfide isomerase family A, member 2 [EC:5.3.4.1] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like domain;; Thioredoxin-like;; Thioredoxin-like;; AhpC/TSA family;; Redoxin	Protein disulfide-isomerase A2 (Precursor) GN=PDIA2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein disulfide-isomerase A2 [Ailuropoda melanoleuca]
ENSG00000185619(PCGF3)	--	9.670335298	745	9.672921563	755	10.55022958	751	9.510699102	678	10.92785345	804	10.98913542	726	0.961155257	-0.166427439	normal	0.974120618	0.069158052	normal	0.974747924	-0.057018017	normal	0.872387282	-0.048742643	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K11488|1.19978e-180|ptr:461045|PCGF3; polycomb group ring finger 3; K11488 polycomb group RING finger protein 3 (A)	Signaling pathways regulating pluripotency of stem cells (ko04550)	[S]	Function unknown	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	Polycomb group RING finger protein 3 GN=PCGF3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polycomb group RING finger protein 3 [Ceratotherium simum simum] 
ENSG00000185621(LMLN)	--	1.716850455	222	2.809007126	297	2.832491	266	3.0623396	352	1.913993489	243	3.230540062	396	0.138287794	0.630689492	normal	0.894550381	-0.309189373	normal	0.271816892	0.563142061	normal	0.425100537	0.315201736	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Biological Process: cell adhesion (GO:0007155);; Cellular Component: membrane (GO:0016020);; 	"K13539|0|hsa:89782|LMLN, GP63, INV, IX14, MSP; leishmanolysin-like (metallopeptidase M8 family) (EC:3.4.24.36); K13539 leishmanolysin-like peptidase [EC:3.4.24.-] (A)"	--	[MV]	Cell wall/membrane/envelope biogenesis;; Defense mechanisms	Leishmanolysin	Leishmanolysin-like peptidase GN=LMLN OS=Homo sapiens (Human) PE=2 SV=2	MV	Cell wall/membrane/envelope biogenesis;; Defense mechanisms	PREDICTED: leishmanolysin-like peptidase isoform X1 [Galeopterus variegatus]
ENSG00000185624(P4HB)	--	374.7900818	19386	345.4458214	17965	331.5286897	17281	435.8562961	22148	398.9800087	20242	441.6507468	22805	0.99648375	0.16131704	normal	0.996349253	0.15072439	normal	0.946704623	0.391842082	normal	0.269706369	0.233751058	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	"K09580|0|hsa:5034|P4HB, DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB; prolyl 4-hydroxylase, beta polypeptide (EC:5.3.4.1); K09580 protein disulfide-isomerase A1 [EC:5.3.4.1] (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like domain;; Thioredoxin-like;; Thioredoxin-like;; ERp29, N-terminal domain;; AhpC/TSA family;; Redoxin"	Protein disulfide-isomerase (Precursor) GN=P4HB OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein disulfide-isomerase isoform X2 [Pantholops hodgsonii]
ENSG00000185627(PSMD13)	--	59.8403971	1695	59.3662431	1706	59.43038009	1688	75.40330651	2182	73.21017577	2087	56.22552107	1699	0.890875682	0.333266727	normal	0.946173326	0.269170358	normal	0.985305839	0.001078543	normal	0.246159917	0.20796084	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K03039|0|hsa:5719|PSMD13, HSPC027, Rpn9, S11, p40.5; proteasome (prosome, macropain) 26S subunit, non-ATPase, 13; K03039 26S proteasome regulatory subunit N9 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	PCI domain	26S proteasome non-ATPase regulatory subunit 13 GN=PSMD13 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 13 isoform X1 [Vicugna pacos]
ENSG00000185630(PBX1)	--	63.81310248	5373	54.59935834	4748	55.53562968	5039	37.47569966	3408	45.45305813	4047	37.75645547	3075	0.007855863	-0.687385625	normal	0.973557469	-0.251806664	normal	0.003017007	-0.720562774	normal	0.000185676	-0.54710622	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09355|0|ptr:457474|PBX1; pre-B-cell leukemia homeobox 1; K09355 pre-B-cell leukemia transcription factor 1 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	PBC domain;; Homeobox domain;; Homeobox KN domain	Pre-B-cell leukemia transcription factor 1 GN=PBX1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: pre-B-cell leukemia transcription factor 1 isoformX1 [Equus caballus] 
ENSG00000185633(NDUFA4L2)	--	0.87470848	19	1.125378	25	0.743001168	16	0.636595916	14	0.62562968	13	1.74443833	39	--	--	--	0.939306293	-0.889085481	normal	0.538029495	1.202213308	normal	--	--	--	--	--	--	--	--	--	--	NADH-ubiquinone reductase complex 1 MLRQ subunit	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 GN=NDUFA4L2 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2 [Orcinus orca] 
ENSG00000185634(SHC4)	--	0.0621904	5	0.054074754	3	0.244779248	7	0.851614	54	0.48898081	39	0.320039	26	2.70E-07	3.060072262	up	2.03E-05	3.148996149	up	0.425505346	1.685130318	normal	1.60E-05	2.965729763	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K17449|0|hsa:399694|SHC4, RaLP, SHCD; SHC (Src homology 2 domain containing) family, member 4; K17449 SHC- transforming protein 4 (A)"	ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Natural killer cell mediated cytotoxicity (ko04650);; Neurotrophin signaling pathway (ko04722);; Insulin signaling pathway (ko04910);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Alcoholism (ko05034);; Bacterial invasion of epithelial cells (ko05100);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	Phosphotyrosine interaction domain (PTB/PID);; SH2 domain	SHC-transforming protein 4 GN=SHC4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SHC-transforming protein 4 isoform X1 [Tupaia chinensis]
ENSG00000185640(KRT79)	--	0	0	0	0	0	0	0	0	0.041753191	1	0.021259538	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:338785|KRT79, K6L, KRT6L; keratin 79; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 79 GN=KRT79 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: keratin, type II cytoskeletal 79 [Galeopterus variegatus]"
ENSG00000185650(ZFP36L1)	--	94.87099545	4656	121.3544433	5835	96.93755284	4720	153.6984921	7501	183.9995971	9048	163.5385879	8124	0.02147906	0.656987339	normal	0.091916619	0.611311532	normal	0.000695045	0.774920406	normal	6.38E-06	0.676705502	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	K18753|0|pps:100977950|ZFP36L1; ZFP36 ring finger protein-like 1; K18753 butyrate response factor 1 (A)	--	[R]	General function prediction only	"Tis11B like protein, N terminus;; Zinc finger C-x8-C-x5-C-x3-H type (and similar)"	"Zinc finger protein 36, C3H1 type-like 1 GN=ZFP36L1 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: zinc finger protein 36, C3H1 type-like 1 isoform X1 [Leptonychotes weddellii] "
ENSG00000185651(UBE2L3)	--	35.20966353	1787	40.23374882	2020	38.93155791	1950	46.3600905	2341	45.7131208	2314	41.45078589	2111	0.856592727	0.358483061	normal	0.977236731	0.174484893	normal	0.983820967	0.106081925	normal	0.235934644	0.211527063	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cellular protein modification process (GO:0006464);; Biological Process: protein transport (GO:0015031);; 	"K04552|1.30758e-129|hsa:7332|UBE2L3, E2-F1, L-UBC, UBCH7, UbcM4; ubiquitin-conjugating enzyme E2L 3 (EC:6.3.2.19); K04552 ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; Prokaryotic E2 family B;; UEV domain;; RWD domain	Ubiquitin-conjugating enzyme E2 L3 GN=UBE2L3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 L3 isoform X1 [Sus scrofa]
ENSG00000185658(BRWD1)	--	7.956002361	1086	7.010754855	1319	7.962784	1156	7.1281088	1149	6.57909412	1147	7.18773882	1190	0.979904299	0.050453035	normal	0.955261814	-0.222731616	normal	0.981038773	0.033485557	normal	0.845964132	-0.051907566	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K11798|0|ptr:473998|BRWD1, C21orf107; bromodomain and WD repeat domain containing 1; K11798 bromodomain and WD repeat domain containing protein 1/3 (A)"	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Bromodomain"	Bromodomain and WD repeat-containing protein 1 GN=BRWD1 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: bromodomain and WD repeat-containing protein 1 [Camelus dromedarius]
ENSG00000185664(PMEL)	--	0.984865275	41	0.928065017	27	0.929412914	32	0.487947494	21	0.621195186	28	1.136488	48	0.783384872	-0.945663173	normal	0.984869557	0.029422593	normal	0.93866221	0.555118694	normal	0.962494755	-0.062697752	normal	--	--	--	"K17304|0|ptr:451977|PMEL, SILV; premelanosome protein; K17304 melanocyte protein PMEL (A)"	--	--	--	PKD domain	M-beta (Precursor) GN=PMEL OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: melanocyte protein PMEL isoform X1 [Galeopterus variegatus]
ENSG00000185666(SYN3)	--	0.16692412	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	"Synapsin, ATP binding domain;; Synapsin, N-terminal domain;; Synapsin N-terminal;; RimK-like ATP-grasp domain"	Synapsin-3 GN=SYN3 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synapsin-3 isoform X2 [Ursus maritimus]
ENSG00000185668(POU3F1)	--	0	0	0	0	0	0	0	0	0	0	0.0294909	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09365|3.69836e-160|ocu:100353061|POU3F1; POU class 3 homeobox 1; K09365 POU domain transcription factor, class 3 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 3, transcription factor 1 GN=POU3F1 OS=Homo sapiens (Human) PE=2 SV=3"	K	Transcription	"PREDICTED: POU domain, class 3, transcription factor 1 [Oryctolagus cuniculus]"
ENSG00000185669(SNAI3)	--	1.00325	29	0.918636	27	2.07336	62	0.512985	15	0.333883	9	1.14969	34	0.915403396	-0.913506388	normal	0.590812247	-1.458824793	normal	0.644276038	-0.84673361	normal	0.323172667	-1.041686677	normal	[R]	General function prediction only	--	"K09217|0|hsa:333929|SNAI3, SMUC, SNAIL3, ZNF293, Zfp293; snail family zinc finger 3; K09217 snail 3 (A)"	--	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein SNAI3 GN=SNAI3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein SNAI3 [Pteropus alecto] 
ENSG00000185670(ZBTB3)	--	1.3642101	73	1.61048521	87	0.96300418	52	1.031728435	55	1.553469944	52	2.452380047	79	0.933623217	-0.428860199	normal	0.569800529	-0.746948298	normal	0.848138311	0.581242359	normal	0.743716327	-0.209634707	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10490|0|hsa:79842|ZBTB3; zinc finger and BTB domain containing 3; K10490 zinc finger and BTB domain-containing protein 3 (A)	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger double domain"	Zinc finger and BTB domain-containing protein 3 GN=ZBTB3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 3 [Orcinus orca]
ENSG00000185674(LYG2)	--	0.080292839	1	0	0	0	0	0.07768642	1	0	0	0.078165663	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transglycosylase SLT domain	Lysozyme g-like protein 2 (Precursor) GN=LYG2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lysozyme g-like protein 2 [Galeopterus variegatus]
ENSG00000185681(MORN5)	--	0.100319	1	0	0	0.192659	1	0	0	0	0	0.131643	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	MORN repeat	MORN repeat-containing protein 5 GN=MORN5 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: MORN repeat-containing protein 5 isoform X1 [Vicugna pacos]
ENSG00000185684(EP400NL)	--	3.17504551	308	4.927146602	311	3.9860777	281	4.357643104	287	3.59586659	294	3.637244734	243	0.959524652	-0.132029369	normal	0.962159992	-0.102014687	normal	0.941793568	-0.216650259	normal	0.653965111	-0.14907433	normal	--	--	--	K11320|2.57256e-180|pps:100992759|EP400 N-terminal-like protein; K11320 E1A-binding protein p400 [EC:3.6.4.-] (A)	--	[R]	General function prediction only	--	EP400 N-terminal-like protein GN=EP400NL OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: E1A-binding protein p400-like [Bos taurus] 
ENSG00000185686(PRAME)	--	69.69024031	2716	52.60886201	2058	58.29266133	2348	67.5131827	2741	89.74332138	3447	49.69019449	1963	0.989454018	-0.017603502	normal	0.003566913	0.72225738	normal	0.950587118	-0.266475703	normal	0.728258727	0.172864325	normal	--	--	--	--	--	--	--	Leucine Rich repeats (2 copies)	Melanoma antigen preferentially expressed in tumors GN=PRAME OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PANDA_020951 [Ailuropoda melanoleuca]
ENSG00000185697(MYBL1)	--	7.477815076	617	8.898006047	723	10.415299	849	11.81225754	999	7.061290432	591	9.118381031	750	0.019114228	0.663072882	normal	0.882917542	-0.311541936	normal	0.958236577	-0.186811114	normal	0.895946735	0.07430382	normal	[KAD]	"Transcription;; RNA processing and modification;; Cell cycle control, cell division, chromosome partitioning"	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09421|0|hsa:4603|MYBL1, A-MYB, AMYB; v-myb avian myeloblastosis viral oncogene homolog-like 1; K09421 myb-related protein (A)"	HTLV-I infection (ko05166)	--	--	"C-myb, C-terminal;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain;; LMSTEN motif"	Myb-related protein A GN=MYBL1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: myb-related protein A isoform 1 [Dasypus novemcinctus]
ENSG00000185716(C16orf52)	--	8.479772	349	10.1538337	412	8.420260853	342	6.98498	276	7.501569	265	9.012574	331	0.825308926	-0.367566529	normal	0.077555615	-0.655054734	normal	0.967191255	-0.055208387	normal	0.138797043	-0.359928511	normal	--	--	--	--	--	--	--	Lipoma HMGIC fusion partner-like protein	Uncharacterized protein C16orf52 GN=C16orf52 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C16orf52 homolog [Oryctolagus cuniculus] 
ENSG00000185721(DRG1)	--	3.124015495	273	2.350596405	208	2.583196984	237	2.454437907	219	2.204837	184	2.6467025	236	0.867137305	-0.346619136	normal	0.948320637	-0.196782005	normal	0.967005029	-0.014300199	normal	0.589111097	-0.189179432	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[T]	Signal transduction mechanisms	TGS domain;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B	Developmentally-regulated GTP-binding protein 1 GN=DRG1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: developmentally-regulated GTP-binding protein 1 isoformX1 [Sus scrofa]
ENSG00000185721(DRG1)-2	--	23.2936	764	23.816	788	26.0155	851	28.1541	931	26.1482	849	23.2856	763	0.932438409	0.253913111	normal	0.973596807	0.085983371	normal	0.963385184	-0.165456826	normal	0.829288191	0.060067001	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000185722(ANKFY1)	--	21.71373168	3161	24.10084491	3508	23.74161098	3444	24.69961588	3583	24.52464816	3549	24.39919465	3550	0.985881091	0.149886287	normal	0.991095096	-0.004660734	normal	0.991069336	0.035427117	normal	0.821676867	0.05779195	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; FYVE zinc finger;; BTB/POZ domain	Rabankyrin-5 {ECO:0000303|PubMed:15328530} GN=ANKFY1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and FYVE domain-containing protein 1 [Condylura cristata]
ENSG00000185728(YTHDF3)	--	22.6894813	1844	25.169483	1949	24.42199497	1850	25.87973957	2087	27.12511861	2094	29.82909576	2335	0.979652157	0.147643999	normal	0.984800846	0.082039374	normal	0.902075702	0.327367127	normal	0.317787679	0.186605765	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	--	--	[R]	General function prediction only	YT521-B-like domain	YTH domain-containing family protein 3 GN=YTHDF3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: YTH domain-containing family protein 3 isoform X1 [Oryctolagus cuniculus] 
ENSG00000185730(ZNF696)	--	6.314081157	390	5.0876056	347	5.650883851	393	5.9101729	353	5.5005545	323	6.3558774	392	0.952745016	-0.173917613	normal	0.960110763	-0.124266561	normal	0.969581634	-0.011921168	normal	0.755656779	-0.102189816	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 696 GN=ZNF696 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 696 [Tursiops truncatus]
ENSG00000185737(NRG3)	--	0	0	0	0	0	0	0.147606754	6	0.071087077	2	0.048363327	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K05457|0|pps:100980498|NRG3; neuregulin 3; K05457 neuregulin 3 (A)	ErbB signaling pathway (ko04012)	--	--	--	Neuregulin-3 (Precursor) GN=NRG3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"PREDICTED: pro-neuregulin-3, membrane-bound isoform-like isoform 1 [Odobenus rosmarus divergens]"
ENSG00000185739(SRL)	--	0	0	0.03738133	3	0	0	0.0319396	2	0.01226021	0	0.0926773	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTP binding (GO:0005525);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Dynamin family;; 50S ribosome-binding GTPase	Sarcalumenin (Precursor) GN=SRL OS=Homo sapiens (Human) PE=2 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sarcalumenin isoform 1 [Dasypus novemcinctus]
ENSG00000185742(C11orf87)	--	0.0246344	2	0.0489039	4	0	0	0.0243982	2	0	0	0.0121688	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf87 (Precursor) GN=C11orf87 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C11orf87 homolog [Tupaia chinensis] 
ENSG00000185745(IFIT1)	--	3.222018	126	2.03296	83	2.844287	117	2.70755	106	2.115687	89	2.546475	107	0.943141496	-0.27651011	normal	0.969891202	0.077896684	normal	0.964961077	-0.135358993	normal	0.821590727	-0.13127521	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	"K14217|0|hsa:3434|IFIT1, C56, G10P1, IFI-56, IFI-56K, IFI56, IFIT-1, IFNAI1, ISG56, P56, RNM561; interferon-induced protein with tetratricopeptide repeats 1; K14217 interferon-induced protein with tetratricopeptide repeats 1 (A)"	Hepatitis C (ko05160);; Herpes simplex infection (ko05168)	[R]	General function prediction only	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Interferon-induced protein with tetratricopeptide repeats 1 GN=IFIT1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: interferon-induced protein with tetratricopeptide repeats 1 [Ailuropoda melanoleuca] 
ENSG00000185753(CXorf38)	--	4.948954	410	4.618067003	371	4.495863199	352	6.023669963	464	6.092809079	486	5.186734603	386	0.959244065	0.147150071	normal	0.811468818	0.366800732	normal	0.96167685	0.124224167	normal	0.397839988	0.215959747	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4559)	Uncharacterized protein CXorf38 GN=CXorf38 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein CXorf38 homolog [Trichechus manatus latirostris]
ENSG00000185760(KCNQ5)	--	1.212233037	97	1.198463756	78	1.353303876	125	0.641670321	76	0.892448051	91	0.43973276	52	0.928203401	-0.376069118	normal	0.962714531	0.197419495	normal	0.000943715	-1.249460119	down	0.282751224	-0.475325752	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04930|0|mcf:102138489|KCNQ5; potassium voltage-gated channel, KQT-like subfamily, member 5; K04930 potassium voltage-gated channel KQT-like subfamily member 5 (A)"	Cholinergic synapse (ko04725)	[P]	Inorganic ion transport and metabolism	KCNQ voltage-gated potassium channel;; Ion transport protein;; Ion channel	Potassium voltage-gated channel subfamily KQT member 5 GN=KCNQ5 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily KQT member 5 isoform X1 [Loxodonta africana]
ENSG00000185761(ADAMTSL5)	--	3.018291286	137	2.502278578	116	2.605784562	120	1.94401531	85	1.49872734	62	2.192870151	77	0.343570026	-0.709273182	normal	0.097006785	-0.908737569	normal	0.599191164	-0.638271831	normal	0.037323733	-0.757373671	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; UNC-6/NTR/C345C module;; Thrombospondin type 1 domain	ADAMTS-like protein 5 (Precursor) GN=ADAMTSL5 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ADAMTS-like protein 5 [Elephantulus edwardii]
ENSG00000185774(KCNIP4)	--	0.466174	14	0.641872	19	1.010297093	29	0.592842	19	0.610084	19	0.624743	19	--	--	--	--	--	--	0.968551535	-0.580682268	normal	--	--	--	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Kv channel-interacting protein 4 GN=KCNIP4 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: Kv channel-interacting protein 4 isoform X1 [Mustela putorius furo] 
ENSG00000185787(MORF4L1)	--	191.4949258	6289	214.6391286	7194	190.6891078	6303	220.3026524	7332	227.8146582	7396	208.4277813	6832	0.989053949	0.190500754	normal	0.994931886	0.018520668	normal	0.99323519	0.107952986	normal	0.664584708	0.102353999	normal	--	--	--	K11339|0|ptr:740309|MORF4L1; mortality factor 4 like 1; K11339 mortality factor 4-like protein 1 (A)	--	[BK]	Chromatin structure and dynamics;; Transcription	MRG;; RNA binding activity-knot of a chromodomain	Mortality factor 4-like protein 1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: mortality factor 4-like protein 1 isoform X1 [Loxodonta africana] 
ENSG00000185792(NLRP9)	--	0.0463859	3	0.015376	1	0.0306789	1	0.030784	2	0.0300745	1	0.0308191	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	NACHT domain;; PAAD/DAPIN/Pyrin domain;; Leucine Rich repeat;; Leucine Rich repeats (2 copies)	"NACHT, LRR and PYD domains-containing protein 9 GN=NLRP9 OS=Homo sapiens (Human) PE=2 SV=1"	R	General function prediction only	"PREDICTED: NACHT, LRR and PYD domains-containing protein 9 [Ceratotherium simum simum]"
ENSG00000185798(WDR53)	--	5.06661	170	5.01986	163	4.748112577	143	5.17544	145	5.6553379	126	6.0585821	166	0.938327514	-0.257788106	normal	0.873024201	-0.388760083	normal	0.951531312	0.204864126	normal	0.755838415	-0.144428972	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 53 GN=WDR53 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 53 [Ceratotherium simum simum]
ENSG00000185803(SLC52A2)	--	53.524566	1565	52.32208804	1553	59.38118372	1789	59.19732205	1769	52.17797804	1568	58.65599715	1750	0.977609333	0.145804437	normal	0.984058065	-0.00755151	normal	0.985285563	-0.040055671	normal	0.911558094	0.030952015	normal	--	--	Cellular Component: integral component of plasma membrane (GO:0005887);; Molecular Function: riboflavin transporter activity (GO:0032217);; Biological Process: riboflavin transport (GO:0032218);; 	--	--	[S]	Function unknown	Protein of unknown function (DUF1011)	"Solute carrier family 52, riboflavin transporter, member 2 GN=SLC52A2 OS=Homo sapiens (Human) PE=1 SV=1"	P	Inorganic ion transport and metabolism	"PREDICTED: solute carrier family 52, riboflavin transporter, member 1 [Equus caballus]"
ENSG00000185808(PIGP)	--	11.20680863	150	11.18454351	160	12.9895079	175	9.369899453	144	9.522018536	121	11.62102378	148	0.965529733	-0.088797532	normal	0.848053191	-0.419911474	normal	0.940560853	-0.24771855	normal	0.532298466	-0.252820708	normal	--	--	--	"K03861|1.55585e-96|hsa:51227|PIGP, DCRC, DCRC-S, DSCR5, DSRC; phosphatidylinositol glycan anchor biosynthesis, class P (EC:2.4.1.198); K03861 phosphatidylinositol glycan, class P (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[S]	Function unknown	PIG-P	Phosphatidylinositol N-acetylglucosaminyltransferase subunit P GN=PIGP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: phosphatidylinositol glycan anchor biosynthesis, class P [Camelus ferus]"
ENSG00000185813(PCYT2)	--	15.21535263	854	12.70869322	816	14.48090697	924	9.78272885	704	10.05722207	661	15.8732934	1078	0.886462191	-0.3088797	normal	0.869602197	-0.324675487	normal	0.954098573	0.213776755	normal	0.825888876	-0.10625355	normal	[MI]	Cell wall/membrane/envelope biogenesis;; Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: biosynthetic process (GO:0009058);; 	"K00967|0|hsa:5833|PCYT2, ET; phosphate cytidylyltransferase 2, ethanolamine (EC:2.7.7.14); K00967 ethanolamine-phosphate cytidylyltransferase [EC:2.7.7.14] (A)"	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Cytidylyltransferase;; FAD synthetase	Ethanolamine-phosphate cytidylyltransferase GN=PCYT2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: ethanolamine-phosphate cytidylyltransferase isoform X1 [Bubalus bubalis]
ENSG00000185818(NAT8L)	--	9.82948332	966	9.36002768	968	9.589839009	983	11.02547886	1093	8.978652311	873	7.387501812	725	0.97028073	0.147145933	normal	0.964043611	-0.170171848	normal	0.557625506	-0.446698458	normal	0.625739872	-0.138772633	normal	[KR]	Transcription;; General function prediction only	Molecular Function: N-acetyltransferase activity (GO:0008080);; 	"K18309|8.89031e-133|hsa:339983|NAT8L, CML3, NACED, NAT8-LIKE; N-acetyltransferase 8-like (GCN5-related, putative) (EC:2.3.1.17); K18309 aspartate N-acetyltransferase [EC:2.3.1.17] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250)"	[R]	General function prediction only	Acetyltransferase (GNAT) family;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain;; Acetyltransferase (GNAT) domain	N-acetylaspartate synthetase GN=NAT8L OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: N-acetylaspartate synthetase [Tupaia chinensis]
ENSG00000185825(BCAP31)	--	182.0010965	4845	177.7680503	4905	179.616726	4945	206.0221013	5508	202.3681488	5303	211.430547	5611	0.98953444	0.154153761	normal	0.992090924	0.091102037	normal	0.988169159	0.17394598	normal	0.513064167	0.139177088	normal	--	--	Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: intracellular protein transport (GO:0006886);; Cellular Component: integral component of membrane (GO:0016021);; 	K14009|0|pps:100976022|BCAP31; B-cell receptor-associated protein 31; K14009 B-cell receptor-associated protein 31 (A)	Protein processing in endoplasmic reticulum (ko04141)	[V]	Defense mechanisms	B-cell receptor-associated protein 31-like	B-cell receptor-associated protein 31 GN=BCAP31 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	PREDICTED: B-cell receptor-associated protein 31 [Oryctolagus cuniculus]
ENSG00000185829(ARL17A)	--	11.463344	846	11.503456	899	13.001925	905	8.961481	650	7.890236	597	11.489306	913	0.685982407	-0.410197472	normal	0.069272817	-0.610746591	normal	0.97850765	0.004398308	normal	0.229974778	-0.315104122	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family	ADP-ribosylation factor-like protein 17 GN=ARL17B OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor 2-like isoform X2 [Lipotes vexillifer]
ENSG00000185838(GNB1L)	--	9.14819829	495	7.636070144	452	8.310194626	527	10.47937475	593	9.884956268	545	9.2762241	593	0.937856733	0.229120897	normal	0.928102938	0.247751103	normal	0.959186319	0.16150058	normal	0.364496697	0.210856478	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat"	Guanine nucleotide-binding protein subunit beta-like protein 1 GN=GNB1L OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: guanine nucleotide-binding protein subunit beta-like protein 1 isoform 1 [Ceratotherium simum simum]
ENSG00000185842(DNAH14)	--	11.82838476	344	11.2430779	352	10.17892753	338	8.89626538	322	8.94451682	311	8.869441318	330	0.960804496	-0.125600148	normal	0.945104061	-0.199176331	normal	0.967692314	-0.042655508	normal	0.707623648	-0.123816953	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Biological Process: microtubule-based movement (GO:0007018);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|pps:100994135|DNAH14; dynein, axonemal, heavy chain 14; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; ATP-binding dynein motor region D5;; P-loop containing dynein motor region D3;; P-loop containing dynein motor region D4;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; ATPase family associated with various cellular activities (AAA);; AAA ATPase domain;; AAA domain;; AAA domain;; AAA domain;; RNA helicase"	"Dynein heavy chain 6, axonemal GN=DNAH6 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: LOW QUALITY PROTEIN: dynein heavy chain 14, axonemal [Galeopterus variegatus]"
ENSG00000185864(NPIPB4)	--	12.1526886	210	11.491679	226	13.81472841	255	9.618802	182	7.081020307	166	11.46752781	203	0.939869803	-0.235430881	normal	0.724387726	-0.462936165	normal	0.882450649	-0.335076753	normal	0.256451241	-0.347267512	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B4 GN=NPIPB4 OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000185869(ZNF829)	--	0.807661302	70	0.589273838	59	0.93149	81	0.381938191	39	0.3770538	38	0.416625044	33	0.543841243	-0.849375255	normal	0.872628685	-0.635675542	normal	0.015379425	-1.26553266	normal	0.039197385	-0.954088408	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|nle:100598705|ZNF829; zinc finger protein 829; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Transposase zinc-ribbon domain"	Zinc finger protein 829 GN=ZNF829 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 829-like [Leptonychotes weddellii]
ENSG00000185873(TMPRSS11B)	--	0	0	0	0	0	0	0	0	0	0	0.0234748	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09751|0|hsa:132724|TMPRSS11B; transmembrane protease, serine 11B; K09751 transmembrane protease, serine 11B [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; SEA domain	Transmembrane protease serine 11B GN=TMPRSS11B OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 11B [Equus caballus]
ENSG00000185875(THNSL1)	--	4.43376	270	4.574001	278	4.88372	291	3.90344	240	3.09051	188	5.61285	343	0.946655717	-0.199551905	normal	0.334475153	-0.581903414	normal	0.93685244	0.227806399	normal	0.772777557	-0.141997945	normal	[E]	Amino acid transport and metabolism	--	--	--	[E]	Amino acid transport and metabolism	Shikimate kinase;; Threonine synthase N terminus;; Pyridoxal-phosphate dependent enzyme;; AAA domain;; ATPase family associated with various cellular activities (AAA)	Threonine synthase-like 1 GN=THNSL1 OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: threonine synthase-like 1 isoform X1 [Galeopterus variegatus] 
ENSG00000185880(TRIM69)	--	5.986970733	218	5.896860822	216	5.116988448	185	3.94622001	145	3.151130099	114	4.831320003	176	0.334730297	-0.613763567	normal	0.004964154	-0.934262384	normal	0.96489933	-0.079574295	normal	0.075616624	-0.529890506	normal	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	K12034|0|ggo:101133745|TRIM69; tripartite motif-containing protein 69 isoform 1; K12034 tripartite motif-containing protein 69 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; RING-type zinc-finger"	E3 ubiquitin-protein ligase TRIM69 GN=TRIM69 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM69 isoform X1 [Camelus ferus]
ENSG00000185888(PRSS38)	--	0	0	0	0	0	0	0	0	0	0	0.0473654	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Serine protease 38 (Precursor) GN=PRSS38 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: serine protease 38 [Panthera tigris altaica]
ENSG00000185896(LAMP1)	--	85.72252	3724	89.56004	3994	81.58775	3624	81.99767	3618	84.35438	3659	100.30726	4419	0.990685744	-0.072462595	normal	0.987101418	-0.147753001	normal	0.962552517	0.277740413	normal	0.940283296	0.023611125	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K06528|0|hsa:3916|LAMP1, CD107a, LAMPA, LGP120; lysosomal-associated membrane protein 1; K06528 lysosomal-associated membrane protein 1/2 (A)"	Lysosome (ko04142);; Phagosome (ko04145);; Tuberculosis (ko05152)	[R]	General function prediction only	Lysosome-associated membrane glycoprotein (Lamp)	Lysosome-associated membrane glycoprotein 1 (Precursor) GN=LAMP1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: lysosome-associated membrane glycoprotein 1 isoformX1 [Canis lupus familiaris]
ENSG00000185900(POMK)	--	2.05011295	287	3.130932699	442	2.0806292	282	2.893660845	406	2.899621599	402	2.806951204	391	0.582271868	0.46748342	normal	0.956287958	-0.157711346	normal	0.608755206	0.461073198	normal	0.526240072	0.224219223	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17547|0|hsa:84197|POMK, MDDGA12, MDDGC12, SGK196; protein-O-mannose kinase (EC:2.7.1.183); K17547 glycoprotein-mannosyl O6-kinase [EC:2.7.1.183] (A)"	--	--	--	Protein tyrosine kinase;; Protein kinase domain	Protein O-mannose kinase GN=POMK OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein O-mannose kinase [Orycteropus afer afer]
ENSG00000185909(KLHDC8B)	--	7.088505128	232	6.3891935	216	5.982934882	203	4.742773284	158	5.183976	169	4.09571829	136	0.402619976	-0.580343955	normal	0.859681787	-0.37247825	normal	0.467001835	-0.580842179	normal	0.079225387	-0.513352284	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Kelch domain-containing protein 8B GN=KLHDC8B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: kelch domain-containing protein 8B [Oryctolagus cuniculus]
ENSG00000185915(KLHL34)	--	0.0859882	5	0	0	0.0974777	5	0.0168839	1	0.0331772	1	0.0676627	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K10469|0|hsa:257240|KLHL34; kelch-like family member 34; K10469 kelch-like protein 34 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Galactose oxidase, central domain;; BTB/POZ domain;; Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; BTB And C-terminal Kelch"	Kelch-like protein 34 GN=KLHL34 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 34 [Odobenus rosmarus divergens]
ENSG00000185917(SETD4)	--	5.859775354	226	5.023779892	237	6.7171835	247	5.189199304	211	6.203851841	238	6.164933361	259	0.960001078	-0.129004102	normal	0.965878559	-0.015254909	normal	0.965759255	0.059792087	normal	0.964587023	-0.024519124	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Rubisco LSMT substrate-binding;; SET domain	SET domain-containing protein 4 GN=SETD4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SET domain-containing protein 4 isoform 1 [Dasypus novemcinctus] 
ENSG00000185920(PTCH1)	--	2.593474839	343	4.328717711	363	2.658643717	351	1.779274388	180	1.710691966	174	1.623983805	216	0.000339646	-0.955030305	normal	2.05E-05	-1.075685205	down	0.043682305	-0.704821474	normal	2.24E-05	-0.911632211	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06225|0|hsa:5727|PTCH1, BCNS, HPE7, NBCCS, PTC, PTC1, PTCH, PTCH11; patched 1; K06225 patched 1 (A)"	cAMP signaling pathway (ko04024);; Hedgehog signaling pathway (ko04340);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Patched family;; Sterol-sensing domain of SREBP cleavage-activation	Protein patched homolog 1 GN=PTCH1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein patched homolog 1 isoform X2 [Orycteropus afer afer]
ENSG00000185924(RTN4RL1)	--	0.205286	14	0.100566	7	0.02801	1	1.13535	78	1.30168	89	1.03663	72	3.33E-07	2.326947874	up	4.82E-13	3.391151433	up	6.22E-15	4.865202867	up	1.55E-12	3.417991491	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16660|0|hsa:146760|RTN4RL1, NGRH2, NgR3; reticulon 4 receptor-like 1; K16660 reticulon-4 receptor-like 1 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies)	Reticulon-4 receptor-like 1 (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: reticulon-4 receptor-like 1 [Equus caballus]
ENSG00000185933(CALHM1)	--	0	0	0	0	0	0	0.0171837	1	0.0505411	2	0.0171042	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Calcium homeostasis modulator	Calcium homeostasis modulator protein 1 GN=CALHM1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: calcium homeostasis modulator protein 1 [Oryctolagus cuniculus]
ENSG00000185942(NKAIN3)	--	0.16441206	5	0.067686194	2	0.291396051	8	0.48281705	15	0.31926115	9	0.22714131	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	"Na,K-Atpase Interacting protein"	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3 GN=NKAIN3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC101672226 [Mustela putorius furo]
ENSG00000185946(RNPC3)	--	6.37531313	286	7.380508243	302	5.429436862	240	5.684767908	218	5.355654618	258	6.136325683	264	0.760577244	-0.419926315	normal	0.928950023	-0.247262822	normal	0.95989515	0.128440166	normal	0.577640612	-0.18304834	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13157|0|hsa:55599|RNPC3, RBM40, RNP, SNRNP65; RNA-binding region (RNP1, RRM) containing 3; K13157 U11/U12 small nuclear ribonucleoprotein 65 kDa protein (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 40 GN=RNPC3 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein 40 isoform X1 [Vicugna pacos]
ENSG00000185947(ZNF267)	--	6.06	354	5.029483631	290	5.64165	321	5.950087001	351	5.063818771	296	4.903261	287	0.967933953	-0.0429235	normal	0.966707871	0.008076033	normal	0.953395325	-0.168971635	normal	0.860328988	-0.068919803	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:467965|ZNF267; zinc finger protein 267; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 267 GN=ZNF267 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 99-like [Canis lupus familiaris]
ENSG00000185950(IRS2)	--	10.0853	1320	11.85	1565	9.46712	1267	8.16584	1076	6.9894	922	14.6312	1941	0.879429372	-0.325271897	normal	0.000776895	-0.783751695	normal	0.05073214	0.606502958	normal	0.902758197	-0.095636116	normal	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	"K07187|0|hsa:8660|IRS2, IRS-2; insulin receptor substrate 2; K07187 insulin receptor substrate 2 (A)"	cGMP-PKG signaling pathway (ko04022);; FoxO signaling pathway (ko04068);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; MicroRNAs in cancer (ko05206)	--	--	PTB domain (IRS-1 type);; PH domain	Insulin receptor substrate 2 GN=IRS2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: insulin receptor substrate 2 [Ceratotherium simum simum]
ENSG00000185955(C7orf61)	--	0.3234357	3	0.558689	6	0.325284	4	0	0	0.52268809	7	0.133400359	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C7orf61 GN=C7orf61 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein TREES_T100020813 [Tupaia chinensis]
ENSG00000185958(FAM186A)	--	0.02409503	3	0.0498024	2	0.1960109	12	0.097908067	5	0.07104681	4	0.031848393	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM186A GN=FAM186A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM186A [Equus przewalskii]
ENSG00000185963(BICD2)	--	17.62930032	1770	15.24225812	1546	18.45592815	1854	19.6208	1981	19.36750849	1965	13.16825576	1338	0.980769165	0.131539292	normal	0.90037876	0.324280486	normal	0.433766915	-0.478393122	normal	0.985612711	0.009482949	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; Biological Process: transport (GO:0006810);; 	K18739|0|ptr:465233|BICD2; bicaudal D homolog 2 (Drosophila); K18739 protein bicaudal D (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Microtubule-associated protein Bicaudal-D	Protein bicaudal D homolog 2 GN=BICD2 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein bicaudal D homolog 2 isoform X1 [Galeopterus variegatus]
ENSG00000185966(LCE3E)	--	0.174412	1	0	0	0.166085	0	1.00447	6	0.676844	3	0.509066	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Late cornified envelope	--	--	--	--
ENSG00000185972(CCIN)	--	0.06042	2	0	0	0	0	0.0300307	1	0.0588549	1	0.029846	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Kelch motif"	Calicin GN=CCIN OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: calicin [Panthera tigris altaica]
ENSG00000185973(TMLHE)	--	8.849851061	312	8.428428	315	8.2188477	275	8.666682	319	7.900854	291	6.472382	235	0.968061914	0.001172422	normal	0.958166405	-0.135084263	normal	0.936460715	-0.233670713	normal	0.74202305	-0.116478663	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00474|0|mcf:102133795|TMLHE; trimethyllysine hydroxylase, epsilon; K00474 trimethyllysine dioxygenase [EC:1.14.11.8] (A)"	Lysine degradation (ko00310)	[I]	Lipid transport and metabolism	"Taurine catabolism dioxygenase TauD, TfdA family;; Protein of unknown function (DUF971)"	"Trimethyllysine dioxygenase, mitochondrial (Precursor) GN=TMLHE OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: trimethyllysine dioxygenase, mitochondrial isoformX2 [Canis lupus familiaris]"
ENSG00000185988(PLK5)	--	0	0	0	0	0	0	0	0	0	0	0.027850119	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	Inactive serine/threonine-protein kinase PLK5 GN=PLK5 OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	"PREDICTED: LOW QUALITY PROTEIN: inactive serine/threonine-protein kinase PLK5, partial [Galeopterus variegatus]"
ENSG00000185989(RASA3)	--	6.715770205	598	4.697672914	427	5.704327182	524	6.075505788	544	6.159921395	550	4.771482955	430	0.958097232	-0.166921207	normal	0.844621272	0.34269708	normal	0.898366085	-0.292587838	normal	0.910957211	-0.045173538	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; Biological Process: regulation of GTPase activity (GO:0043087);; 	"K12380|0|hsa:22821|RASA3, GAP1IP4BP, GAPIII; RAS p21 protein activator 3; K12380 Ras GTPase-activating protein 3 (A)"	Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	GTPase-activator protein for Ras-like GTPase;; C2 domain;; BTK motif;; PH domain	Ras GTPase-activating protein 3 GN=RASA3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating protein 3 [Pteropus alecto]
ENSG00000186001(LRCH3)	--	7.024702398	547	7.914452	541	8.14092482	592	7.372818004	612	7.220200456	587	7.641651713	642	0.964818648	0.130811079	normal	0.968073595	0.096047558	normal	0.968585647	0.108418662	normal	0.681482001	0.111116405	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Calponin homology (CH) domain;; Leucine rich repeat;; CAMSAP CH domain	Leucine-rich repeat and calponin homology domain-containing protein 3 (Precursor) GN=LRCH3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: leucine-rich repeat and calponin homology domain-containing protein 3 isoform X1 [Camelus bactrianus]
ENSG00000186010(NDUFA13)	--	73.8780559	1089	74.03574613	1071	78.94475499	1126	86.97535588	1183	76.64539642	1124	86.5638	1208	0.97806902	0.08849405	normal	0.979338758	0.048190573	normal	0.978154892	0.093001572	normal	0.759638398	0.076121073	normal	--	--	--	"K11353|1.68631e-70|hsa:51079|NDUFA13, B16.6, CDA016, GRIM-19, GRIM19; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13; K11353 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 13 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[CD]	"Energy production and conversion;; Cell cycle control, cell division, chromosome partitioning"	GRIM-19 protein	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 GN=NDUFA13 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 [Canis lupus familiaris]
ENSG00000186017(ZNF566)	--	6.372206853	386	6.990921217	465	5.373964398	338	4.014174179	263	5.3938918	273	5.290090399	369	0.220603176	-0.581547046	normal	0.005307002	-0.786377159	normal	0.96223606	0.117801544	normal	0.165684383	-0.414378092	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:84924|ZNF566; zinc finger protein 566; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; BED zinc finger;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 566 GN=ZNF566 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 566 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000186020(ZNF529)	--	3.932418545	258	3.587766957	222	3.828089033	210	3.950493	235	2.735436339	179	3.467997423	226	0.954391984	-0.164515502	normal	0.892834167	-0.329521418	normal	0.963224262	0.096968743	normal	0.739939017	-0.130158662	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:57711|ZNF529; zinc finger protein 529; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; NTF2 fold immunity protein;; TFIIH C1-like domain"	Zinc finger protein 529 GN=ZNF529 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	"PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 529, partial [Galeopterus variegatus]"
ENSG00000186026(ZNF284)	--	1.783192	148	1.461354257	125	1.4773733	122	1.502275511	124	1.909010071	156	1.553594726	135	0.935403874	-0.282876014	normal	0.928015959	0.29499122	normal	0.963217649	0.136181484	normal	0.93870179	0.050251975	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:342909|ZNF284, ZNF284L; zinc finger protein 284; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; BolA-like protein;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 284 GN=ZNF284 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein-like [Galeopterus variegatus]
ENSG00000186047(DLEU7)	--	0.0295016	1	0.057534	2	0.0568206	1	0	0	0.0285004	0	0.0578478	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Leukemia-associated protein 7 GN=DLEU7 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leukemia-associated protein 7 [Balaenoptera acutorostrata scammoni]
ENSG00000186051(TAL2)	--	0	0	0	0	0.119906	0	0.243182	2	0.125147	0	0.48325	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09068|5.96742e-74|ptr:473010|TAL2; T-cell acute lymphocytic leukemia 2; K09068 T-cell acute lymphocytic leukemia protein (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	T-cell acute lymphocytic leukemia protein 2 GN=TAL2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: T-cell acute lymphocytic leukemia protein 2 isoform X1 [Tupaia chinensis] 
ENSG00000186063(AIDA)	--	44.06261785	2171	43.60330924	2162	50.70270607	2472	50.141691	2498	42.63400975	2095	46.74960966	2311	0.978949144	0.171468296	normal	0.985960611	-0.06679537	normal	0.985600145	-0.105386231	normal	1	-0.00042064	normal	--	--	--	--	--	--	--	Cytoskeletal adhesion;; Aida N-terminus	"Axin interactor, dorsalization-associated protein GN=AIDA OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: axin interactor, dorsalization-associated protein isoform X1 [Vicugna pacos] "
ENSG00000186073(C15orf41)	--	7.306750948	303	7.442957525	237	10.12285737	305	10.14624003	344	8.848051279	313	7.372723194	303	0.956701618	0.151537035	normal	0.82236311	0.377745668	normal	0.967815629	-0.017694865	normal	0.607130665	0.162762201	normal	--	--	--	--	--	--	--	Protein of unknown function TPD sequence-motif	Uncharacterized protein C15orf41 GN=C15orf41 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C15orf41 homolog isoform 1 [Dasypus novemcinctus]
ENSG00000186081(KRT5)	--	0	0	0.118590292	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07605|0|hsa:3852|KRT5, CK5, DDD, DDD1, EBS2, K5, KRT5A; keratin 5; K07605 type II keratin, basic (A)"	--	--	--	Intermediate filament protein	"Keratin, type II cytoskeletal 5 GN=KRT5 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: keratin, type II cytoskeletal 5 [Equus przewalskii]"
ENSG00000186088(GSAP)	--	5.9106959	323	5.433277418	284	5.396759039	270	5.849281	321	5.25268166	284	6.3962899	351	0.967497171	-0.039604157	normal	0.966391969	-0.021313069	normal	0.825468534	0.368405489	normal	0.773383369	0.103278562	normal	--	--	--	--	--	--	--	gamma-Secretase-activating protein C-term	Gamma-secretase-activating protein 16 kDa C-terminal form GN=GSAP OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: gamma-secretase-activating protein [Tupaia chinensis]
ENSG00000186104(CYP2R1)	--	6.1973284	402	5.59572007	353	6.582648101	398	7.081202225	409	6.801738	403	7.054703315	426	0.969790395	-0.005904549	normal	0.953143534	0.169007087	normal	0.966321368	0.089464926	normal	0.810300485	0.081664835	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07419|0|hsa:120227|CYP2R1; cytochrome P450, family 2, subfamily R, polypeptide 1 (EC:1.14.13.159); K07419 vitamin D 25-hydroxylase [EC:1.14.13.159] (A)"	Steroid biosynthesis (ko00100)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Vitamin D 25-hydroxylase GN=CYP2R1 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: vitamin D 25-hydroxylase [Eptesicus fuscus]
ENSG00000186106(ANKRD46)	--	4.946365183	161	5.320670934	177	4.567808201	150	6.460417815	206	7.42037925	233	7.714431355	240	0.904343789	0.322028987	normal	0.854520691	0.372373414	normal	0.178245921	0.664437685	normal	0.123402939	0.455597113	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 46 GN=ANKRD46 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 46 isoform X2 [Bison bison bison]
ENSG00000186111(PIP5K1C)	--	8.730392385	876	8.794024937	880	9.385574079	945	9.373353831	907	9.240699	926	9.494195264	951	0.978064922	0.01930614	normal	0.97681761	0.051995003	normal	0.979001465	0.000838232	normal	0.947602983	0.022756511	normal	[T]	Signal transduction mechanisms	Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; 	"K00889|0|mcf:102133242|PIP5K1C; phosphatidylinositol-4-phosphate 5-kinase, type I, gamma; K00889 1-phosphatidylinositol-4-phosphate 5-kinase [EC:2.7.1.68] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Endocytosis (ko04144);; Fc gamma R-mediated phagocytosis (ko04666);; Regulation of actin cytoskeleton (ko04810);; Choline metabolism in cancer (ko05231)	[T]	Signal transduction mechanisms	Phosphatidylinositol-4-phosphate 5-Kinase	Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma GN=PIP5K1C OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-phosphate 5-kinase type-1 gamma isoform X1 [Bubalus bubalis]
ENSG00000186115(CYP4F2)	--	0	0	0.048736503	2	0	0	0	0	0	0	0.048361157	2	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	K17726|0|ptr:748531|leukotriene-B(4) omega-hydroxylase 1; K17726 leukotriene-B4 20-monooxygenase / phylloquinone omega-hydroxylase [EC:1.14.13.30 1.14.13.194] (A)	Arachidonic acid metabolism (ko00590)	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Docosahexaenoic acid omega-hydroxylase CYP4F3 {ECO:0000305} GN=CYP4F3 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: leukotriene-B(4) omega-hydroxylase 2 isoform X1 [Ursus maritimus]
ENSG00000186118(TEX38)	--	0	0	0	0	0	0	0	0	0.243347834	1	0.071360257	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testis-expressed sequence 38 protein GN=TEX38 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: testis-expressed sequence 38 protein [Odobenus rosmarus divergens]
ENSG00000186130(ZBTB6)	--	6.0626	347	6.50589	369	5.56113	309	5.63079	325	5.81568	332	5.58135	319	0.960959104	-0.12475726	normal	0.951847984	-0.173115725	normal	0.967515927	0.037477617	normal	0.794544555	-0.092166626	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10493|0|ptr:473054|ZBTB6, ZNF482; zinc finger and BTB domain containing 6; K10493 zinc finger and BTB domain-containing protein 6 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger and BTB domain-containing protein 6 GN=ZBTB6 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 6 [Trichechus manatus latirostris]
ENSG00000186132(C2orf76)	--	10.84287202	98	11.03441077	98	13.44691037	121	4.155860504	37	6.2821131	56	5.8268199	54	0.00081387	-1.398980358	down	0.34680496	-0.811986496	normal	0.004538213	-1.150174721	down	0.002770708	-1.128295406	down	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2340)	UPF0538 protein C2orf76 GN=C2orf76 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: UPF0538 protein C2orf76 homolog isoform X1 [Pteropus alecto] 
ENSG00000186136(TAS2R42)	--	0	0	0	0	0	0	0.110808	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|4.14659e-173|hsa:353164|TAS2R42, T2R24, T2R42, T2R55, TAS2R55; taste receptor, type 2, member 42; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 42 GN=TAS2R42 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 42-like [Ceratotherium simum simum]
ENSG00000186141(POLR3C)	--	8.62382	397	8.783732	395	8.27829	362	10.02067	453	11.1845	507	11.57423	536	0.95679325	0.158963577	normal	0.85274022	0.337563221	normal	0.22555455	0.556031071	normal	0.10190399	0.353646257	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; "	K03023|0|ptr:457224|POLR3C; polymerase (RNA) III (DNA directed) polypeptide C (62kD); K03023 DNA-directed RNA polymerase III subunit RPC3 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase III subunit RPC82;; RNA polymerase III subunit RPC82 helix-turn-helix domain	DNA-directed RNA polymerase III subunit RPC3 GN=POLR3C OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerase III subunit RPC3 [Ceratotherium simum simum]
ENSG00000186150(UBL4B)	--	0.0373083	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like	Ubiquitin-like protein 4B GN=UBL4B OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ubiquitin-like protein 4B [Galeopterus variegatus]
ENSG00000186153(WWOX)	--	10.25305825	308	11.52642306	287	12.76985753	280	10.3543442	187	8.131202084	177	7.61590271	215	0.02952104	-0.745895867	normal	0.064571419	-0.71388902	normal	0.818600999	-0.386989205	normal	0.011141918	-0.616615151	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Molecular Function: protein binding (GO:0005515);; 	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; WW domain;; KR domain;; Enoyl-(Acyl carrier protein) reductase	WW domain-containing oxidoreductase GN=WWOX OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: WW domain-containing oxidoreductase isoform X1 [Oryctolagus cuniculus]
ENSG00000186160(CYP4Z1)	--	0	0	0	0	0	0	0	0	0.0294745	0	0.0300926	1	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07429|0|hsa:199974|CYP4Z1, CYP4A20; cytochrome P450, family 4, subfamily Z, polypeptide 1 (EC:1.14.14.1); K07429 cytochrome P450, family 4, subfamily Z [EC:1.14.14.1] (A)"	--	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 4Z1 GN=CYP4Z1 OS=Homo sapiens (Human) PE=2 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 4Z1-like [Condylura cristata]
ENSG00000186166(CCDC84)	--	4.13899	105	2.85137	73	3.76745	96	4.79882	122	3.7676	94	3.66314	93	0.960368286	0.183171405	normal	0.939677717	0.337168485	normal	0.97079277	-0.05324293	normal	0.792657495	0.151531265	normal	--	--	--	--	--	--	--	Coiled coil protein 84	Coiled-coil domain-containing protein 84 GN=CCDC84 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 84 [Ceratotherium simum simum]
ENSG00000186174(BCL9L)	--	34.320798	5927	37.93549286	5971	34.041898	5953	38.34865955	6176	38.36803256	6498	48.09381667	7741	0.994273128	0.028531186	normal	0.992989725	0.100572195	normal	0.915254353	0.370528841	normal	0.396302255	0.173108623	normal	--	--	--	--	--	--	--	B-cell lymphoma 9 protein	B-cell CLL/lymphoma 9-like protein GN=BCL9L OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: B-cell CLL/lymphoma 9-like protein [Camelus bactrianus]
ENSG00000186184(POLR1D)	--	54.4728376	1167	56.26584073	1227	50.23417919	1133	58.64133835	1269	50.28901879	1099	54.9487542	1199	0.978842099	0.089941674	normal	0.965921599	-0.180135682	normal	0.979421444	0.073297242	normal	0.989936683	-0.005259474	normal	[K]	Transcription	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: protein dimerization activity (GO:0046983);; "	K03020|1.14661e-95|ptr:452506|POLR1D; DNA-directed RNA polymerases I and III subunit RPAC2; K03020 DNA-directed RNA polymerases I and III subunit RPAC2 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Cytosolic DNA-sensing pathway (ko04623);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpb3/Rpb11 dimerisation domain;; RNA polymerase Rpb3/Rpb11 dimerisation domain	DNA-directed RNA polymerases I and III subunit RPAC2 GN=POLR1D OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: DNA-directed RNA polymerases I and III subunit RPAC2 [Galeopterus variegatus]
ENSG00000186185(KIF18B)	--	16.18177583	1439	16.47528608	1461	15.85706479	1423	12.54078117	1096	13.20191288	1161	12.53313213	1114	0.651485606	-0.423131543	normal	0.847420809	-0.352604323	normal	0.824923657	-0.361043081	normal	0.016111723	-0.380003765	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	--	--	--	--	Kinesin motor domain	Kinesin-like protein KIF18B GN=KIF18B OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: kinesin family member 18B isoform X1 [Equus caballus]
ENSG00000186187(ZNRF1)	--	28.449949	621	26.652108	593	26.87244425	589	26.651203	612	26.80182597	588	30.979245	659	0.972792688	-0.051764864	normal	0.972379741	-0.033556568	normal	0.962138906	0.153346987	normal	0.952688398	0.023092574	normal	--	--	--	"K10694|1.76269e-155|ptr:736544|ZNRF1; zinc and ring finger 1, E3 ubiquitin protein ligase; K10694 E3 ubiquitin-protein ligase ZNRF1/2 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ring finger domain	E3 ubiquitin-protein ligase ZNRF1 GN=ZNRF1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase ZNRF1 [Felis catus] 
ENSG00000186188(FFAR4)	--	0.335178948	21	0.3041509	19	0.434681	11	0.790437746	37	0.673860038	32	0.942365	28	0.925027544	0.744796217	normal	0.948667946	0.68804856	normal	0.78120733	1.230392243	normal	0.16012779	0.904522018	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08425|0|pon:100441471|FFAR4, O3FAR1; free fatty acid receptor 4; K08425 G protein-coupled receptor 120 (A)"	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Free fatty acid receptor 4 GN=FFAR4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: free fatty acid receptor 4 isoform X1 [Mustela putorius furo] 
ENSG00000186193(SAPCD2)	--	10.8208	827	10.0067	790	9.00848	718	13.0139	998	12.3081	938	8.42161	650	0.941325485	0.239914023	normal	0.946544512	0.225911438	normal	0.963705881	-0.151500042	normal	0.730266202	0.124748856	normal	--	--	--	--	--	--	--	Adenomatous polyposis coli tumour suppressor protein	Suppressor APC domain-containing protein 2 GN=SAPCD2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: suppressor APC domain-containing protein 2 [Orcinus orca]
ENSG00000186197(EDARADD)	--	2.237726466	151	1.746584663	127	2.434480997	155	2.643009729	183	3.246342236	210	3.79373649	267	0.940857785	0.2442031	normal	0.169581817	0.697611269	normal	0.03156531	0.770484145	normal	0.039985825	0.588280013	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	Death domain	Ectodysplasin-A receptor-associated adapter protein GN=EDARADD OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ectodysplasin-A receptor-associated adapter protein isoform X1 [Canis lupus familiaris]
ENSG00000186198(SLC51B)	--	1.708363	29	1.551817	27	1.7905044	30	1.862647	32	2.485543	41	9.4539	162	0.984450886	0.105847192	normal	0.949637523	0.555818878	normal	1.39E-13	2.367358493	up	0.469629786	1.433914513	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Cellular Component: plasma membrane (GO:0005886);; Biological Process: bile acid and bile salt transport (GO:0015721);; Molecular Function: protein heterodimerization activity (GO:0046982);; 	"K14361|5.83634e-86|pon:100431956|SLC51B; solute carrier family 51, beta subunit; K14361 organic solute transporter subunit beta (A)"	Bile secretion (ko04976)	--	--	Organic solute transporter subunit beta protein	Organic solute transporter subunit beta GN=SLC51B OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: organic solute transporter subunit beta isoform X1 [Equus caballus] 
ENSG00000186204(CYP4F12)	--	1.4073306	52	0.9944	41	0.71407858	28	0.2849912	10	0.712501903	30	0.523929859	23	0.000110981	-2.242657323	down	0.96233519	-0.45249675	normal	0.983251981	-0.275633856	normal	0.114069642	-0.961321521	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17730|0|hsa:66002|CYP4F12, CYPIVF12, F22329_1; cytochrome P450, family 4, subfamily F, polypeptide 12 (EC:1.14.14.1); K17730 cytochrome P450, family 4, subfamily F, polypeptide 12 [EC:1.14.14.1] (A)"	--	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 4F12 GN=CYP4F12 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: cytochrome P450, family 4, subfamily F, polypeptide 2 isoform X1 [Bos taurus] "
ENSG00000186205(MARC1)	--	11.40323384	234	12.57527513	290	12.75076759	310	12.66774995	330	11.07774274	332	10.04384683	277	0.641073416	0.462556842	normal	0.95152406	0.172860815	normal	0.953206209	-0.169796898	normal	0.645570781	0.149687799	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: molybdenum ion binding (GO:0030151);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	--	--	[R]	General function prediction only	MOSC N-terminal beta barrel domain;; MOSC domain	Mitochondrial amidoxime-reducing component 1 GN=MARC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"PREDICTED: MOSC domain-containing protein 1, mitochondrial [Orcinus orca]"
ENSG00000186207(LCE5A)	--	0.0920385	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: epidermis development (GO:0008544);; 	--	--	--	--	Late cornified envelope	--	--	--	--
ENSG00000186212(SOWAHB)	--	0.19512	12	0.0157373	1	0.0308701	1	0.0967405	6	0.110098	6	0.0320807	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein SOWAHB GN=SOWAHB OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein SOWAHB [Dasypus novemcinctus]
ENSG00000186222(BLOC1S4)	--	9.80579	239	9.06152	228	7.78264	196	10.6253	262	12.8497	314	10.0545	246	0.962783681	0.101103053	normal	0.715450761	0.437820175	normal	0.897930757	0.317323369	normal	0.329270712	0.288582323	normal	--	--	--	"K08366|3.01104e-139|ptr:461105|BLOC1S4, CNO; biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino; K08366 cappuccino (A)"	--	--	--	--	Biogenesis of lysosome-related organelles complex 1 subunit 4 GN=BLOC1S4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: biogenesis of lysosome-related organelles complex 1 subunit 4 [Ceratotherium simum simum]
ENSG00000186226(LCE1E)	--	0	0	0	0	0.125506	1	0	0	0	0	0.170193116	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: epidermis development (GO:0008544);; 	--	--	--	--	Late cornified envelope	--	--	--	--
ENSG00000186230(ZNF749)	--	5.244788	340	4.704725	400	4.417369	321	5.100246	350	4.029936	343	7.183573	424	0.968548484	0.010939191	normal	0.92960007	-0.242227879	normal	0.771632312	0.391589396	normal	0.890794781	0.05328479	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:388567|ZNF749; zinc finger protein 749; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; XPA protein N-terminal;; C2H2-type zinc finger;; Ring hydroxylating beta subunit;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 749 GN=ZNF749 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 850-like [Orcinus orca]
ENSG00000186231(KLHL32)	--	0.050404751	3	0	0	0	0	0.079321692	3	0.115972429	0	0.016748913	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K10468|0|pon:100454911|KLHL32; kelch-like family member 32; K10468 kelch-like protein 32 (A)	--	[R]	General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 32 GN=KLHL32 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: kelch-like protein 32 isoform X3 [Canis lupus familiaris]
ENSG00000186260(MKL2)	--	17.6640782	1905	16.5203523	1991	14.47164961	1878	14.32720168	1592	14.5307183	1782	15.58434723	1583	0.929618496	-0.289527066	normal	0.973986629	-0.181276808	normal	0.950266445	-0.254603649	normal	0.16382782	-0.24132094	normal	--	--	--	--	--	--	--	RPEL repeat;; SAP domain	MKL/myocardin-like protein 2 GN=MKL2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: MKL/myocardin-like protein 2 isoform X1 [Galeopterus variegatus] 
ENSG00000186265(BTLA)	--	0.0394007	2	0	0	0	0	0	0	0	0	0.106825014	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06707|0|ptr:460584|BTLA; B and T lymphocyte associated; K06707 B- and T-lymphocyte attenuator (A)	--	--	--	Immunoglobulin domain	B- and T-lymphocyte attenuator (Precursor) GN=BTLA OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: b- and T-lymphocyte attenuator isoform 1 [Ceratotherium simum simum]
ENSG00000186280(KDM4D)	--	0.449307174	25	0.381455831	19	0.267823408	14	0.223675258	9	0.104588907	5	0.195412188	11	0.757257412	-1.360277246	normal	--	--	--	--	--	--	--	--	--	--	--	--	"K06709|0|hsa:55693|KDM4D, JMJD2D; lysine (K)-specific demethylase 4D; K06709 jumonji domain-containing protein 2 [EC:1.14.11.-] (A)"	--	[L]	"Replication, recombination and repair"	"JmjC domain, hydroxylase;; jmjN domain"	Lysine-specific demethylase 4D GN=KDM4D OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: lysine-specific demethylase 4D [Orycteropus afer afer]
ENSG00000186281(GPAT2)	--	0	0	0.204782002	9	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K00629|0|hsa:150763|GPAT2, CT123; glycerol-3-phosphate acyltransferase 2, mitochondrial (EC:2.3.1.15); K00629 glycerol-3-phosphate O-acyltransferase 1/2 [EC:2.3.1.15] (A)"	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564)	--	--	--	"Glycerol-3-phosphate acyltransferase 2, mitochondrial GN=GPAT2 OS=Homo sapiens (Human) PE=2 SV=2"	I	Lipid transport and metabolism	"PREDICTED: glycerol-3-phosphate acyltransferase 2, mitochondrial [Equus caballus]"
ENSG00000186283(TOR3A)	--	39.20935	1150	50.65347	1336	58.20844	1345	52.89007	1169	46.24734	1136	46.10778	1056	0.98122465	-0.007181678	normal	0.941528668	-0.255070217	normal	0.830551755	-0.356833826	normal	0.258928428	-0.210200454	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	[R]	General function prediction only	Torsin	Torsin-3A (Precursor) GN=TOR3A OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: torsin-3A [Loxodonta africana]
ENSG00000186288(PABPC1L2A)	--	0	0	0	0	0	0	0.0565212	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13126|1.98555e-148|ocu:100356494|PABPC1L2B; poly(A) binding protein, cytoplasmic 1-like 2B; K13126 polyadenylate-binding protein (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; RNA degradation (ko03018)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Nup53/35/40-type RNA recognition motif"	Polyadenylate-binding protein 1-like 2 GN=PABPC1L2B OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	TPA: PABPC1L2B protein-like [Bos taurus]
ENSG00000186297(GABRA5)	--	40.36525627	1978	36.4749581	1731	42.19549	2108	33.263027	1603	38.295867	1914	33.917698	1712	0.886129634	-0.333811601	normal	0.980865725	0.123455947	normal	0.917705472	-0.308237765	normal	0.357941178	-0.174399776	normal	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05175|0|pps:100970387|GABRA5; gamma-aminobutyric acid (GABA) A receptor, alpha 5; K05175 gamma-aminobutyric acid receptor subunit alpha (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Gamma-aminobutyric acid receptor subunit alpha-5 (Precursor) GN=GABRA5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit alpha-5 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000186298(PPP1CC)	--	88.25890298	3309	80.67341819	3064	87.44286764	3264	114.0281778	4329	109.160767	4089	87.38787389	3309	0.898351687	0.356661094	normal	0.834481823	0.394736035	normal	0.990850383	0.01145752	normal	0.126339016	0.261289473	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K06269|0|ptr:462795|PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme; K06269 serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] (A)"	mRNA surveillance pathway (ko03015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Long-term potentiation (ko04720);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Oxytocin signaling pathway (ko04921);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Herpes simplex infection (ko05168);; Proteoglycans in cancer (ko05205)	[TR]	Signal transduction mechanisms;; General function prediction only	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase PP1-gamma catalytic subunit GN=PPP1CC OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase PP1-gamma catalytic subunit [Ochotona princeps] 
ENSG00000186300(ZNF555)	--	0.97418852	68	2.087193123	66	1.483874786	68	1.0153405	52	1.8604621	69	1.67290859	73	0.944025104	-0.407297001	normal	0.973671483	0.041767764	normal	0.973290306	0.092093222	normal	0.92285607	-0.078408488	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:148254|ZNF555; zinc finger protein 555; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; Transposase zinc-ribbon domain;; Probable zinc-binding domain;; BED zinc finger"	Zinc finger protein 555 GN=ZNF555 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: zinc finger protein 555 isoform X2 [Equus przewalskii]
ENSG00000186310(NAP1L3)	--	0.33130875	16	0.081889365	4	0.20443032	9	0.735864974	36	1.041057848	50	0.410848084	20	0.765271804	1.069084067	normal	3.57E-07	3.206022986	up	0.949349559	1.025680715	normal	0.023169802	1.847756163	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K11281|0|hsa:4675|NAP1L3, MB20, NPL3; nucleosome assembly protein 1-like 3; K11281 nucleosome assembly protein 1-like 3 (A)"	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Nucleosome assembly protein (NAP)	Nucleosome assembly protein 1-like 3 GN=NAP1L3 OS=Homo sapiens (Human) PE=2 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nucleosome assembly protein 1-like 3 [Tupaia chinensis]
ENSG00000186314(PRELID2)	--	4.97828718	178	4.852202938	163	3.878466513	166	5.707479457	241	5.055073853	207	3.701369314	153	0.815345067	0.403322069	normal	0.903044355	0.320686678	normal	0.962158791	-0.124758791	normal	0.550000738	0.222847699	normal	--	--	--	--	--	--	--	PRELI-like family	PRELI domain-containing protein 2 GN=PRELID2 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: PRELI domain-containing protein 2 isoform X1 [Orycteropus afer afer]
ENSG00000186318(BACE1)	--	5.338667238	593	5.428573779	616	5.367004029	596	8.552507555	890	8.2519657	819	8.622168	850	0.169167326	0.55376264	normal	0.75568528	0.388676517	normal	0.341884865	0.502785379	normal	0.004132458	0.482190385	normal	--	--	--	K04521|0|pps:100986447|BACE1; beta-site APP-cleaving enzyme 1; K04521 beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:3.4.23.46] (A)	Alzheimer's disease (ko05010)	[O]	"Posttranslational modification, protein turnover, chaperones"	Eukaryotic aspartyl protease;; Xylanase inhibitor C-terminal	Beta-secretase 1 (Precursor) GN=BACE1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: beta-secretase 1 isoform X1 [Camelus ferus] 
ENSG00000186326(RGS9BP)	--	1.01801	46	0.883806	42	0.55867	26	0.410574	19	0.32038	14	0.52116	24	0.300131105	-1.24002719	normal	0.109502513	-1.50802139	normal	0.986173767	-0.116701652	normal	0.082789713	-1.021402452	normal	--	--	--	--	--	--	--	Syntaxin-like protein	Regulator of G-protein signaling 9-binding protein GN=RGS9BP OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 9-binding protein [Galeopterus variegatus]
ENSG00000186329(TMEM212)	--	0	0	0	0	0	0	0.0276809	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CD20-like family	Transmembrane protein 212 GN=TMEM212 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 212 [Camelus ferus]
ENSG00000186340(THBS2)	--	0.163597192	19	0.180792853	21	0.105190192	11	0.103114674	12	0.066773301	7	0.085246512	10	--	--	--	0.814396305	-1.421898281	normal	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Biological Process: cell adhesion (GO:0007155);; 	"K04659|0|hsa:7058|THBS2, TSP2; thrombospondin 2; K04659 thrombospondin 2/3/4/5 (A)"	Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Malaria (ko05144)	--	--	Thrombospondin C-terminal region;; Thrombospondin type 3 repeat;; Thrombospondin type 1 domain;; von Willebrand factor type C domain;; EGF domain;; Calcium-binding EGF domain;; EGF-like domain	Thrombospondin-2 (Precursor) GN=THBS2 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: thrombospondin-2 [Ceratotherium simum simum]
ENSG00000186350(RXRA)	--	33.22807	2558	30.62016	2500	30.0700737	2471	18.9061299	1674	21.32806	1761	19.762291	1602	0.021696995	-0.642068345	normal	0.267701095	-0.526578112	normal	0.027414514	-0.633027278	normal	2.01E-05	-0.601209177	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08524|0|ptr:464834|RXRA; retinoid X receptor, alpha; K08524 retinoid X receptor alpha (A)"	PPAR signaling pathway (ko03320);; PI3K-Akt signaling pathway (ko04151);; Thyroid hormone signaling pathway (ko04919);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Bile secretion (ko04976);; Hepatitis C (ko05160);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Thyroid cancer (ko05216);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Nuclear/hormone receptor activator site AF-1;; Zinc finger, C4 type (two domains)"	Retinoic acid receptor RXR-alpha GN=RXRA OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: retinoic acid receptor RXR-alpha [Camelus dromedarius]
ENSG00000186352(ANKRD37)	--	1.931057	23	1.737894	21	2.59341	29	3.46201	33	2.452266	23	3.31221	37	0.973179985	0.464011794	normal	0.986875694	0.102746532	normal	0.97646057	0.328005294	normal	0.696661854	0.328883442	normal	--	--	--	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeat	Ankyrin repeat domain-containing protein 37 GN=ANKRD37 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 37 isoform X3 [Capra hircus] 
ENSG00000186354(C9orf47)	--	21.93654543	1613	19.52439053	1448	20.82841372	1536	13.7137717	1018	16.570946	1215	13.5120876	1003	0.006356015	-0.694001003	normal	0.932628342	-0.274218733	normal	0.036851649	-0.622383851	normal	0.000340315	-0.527584738	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf47 (Precursor) GN=C9orf47 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	--
ENSG00000186364(NUDT17)	--	0.933531	27	1.05664	31	0.43392	12	1.09053	32	0.97549	28	2.17092	64	0.983319096	0.203627966	normal	0.982778465	-0.1600486	normal	8.34E-06	2.269761816	up	0.388702871	0.80451269	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	--	--	NUDIX domain	Nucleoside diphosphate-linked moiety X motif 17 GN=NUDT17 OS=Homo sapiens (Human) PE=2 SV=2	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: nucleoside diphosphate-linked moiety X motif 17 [Equus caballus]
ENSG00000186376(ZNF75D)	--	2.461377574	304	3.229619008	306	2.426732328	307	3.594946291	354	3.009063363	352	3.895356638	400	0.948986345	0.187964831	normal	0.950098406	0.179788258	normal	0.811154137	0.371860682	normal	0.353859722	0.249530972	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09229|0|pps:100986577|ZNF75D; zinc finger protein 75D; K09229 KRAB and SCAN domains-containing zinc finger protein (A)	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 75D GN=ZNF75D OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 75D-like isoform X2 [Tupaia chinensis]
ENSG00000186395(KRT10)	--	34.582759	777	38.055185	837	36.166747	794	43.598794	956	44.808956	906	36.23607	884	0.924338714	0.267785706	normal	0.973882023	0.092695868	normal	0.967486071	0.14635163	normal	0.429782446	0.168019011	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3858|KRT10, BCIE, BIE, CK10, EHK, K10, KPP; keratin 10; K07604 type I keratin, acidic (A)"	Staphylococcus aureus infection (ko05150)	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 10 GN=KRT10 OS=Homo sapiens (Human) PE=1 SV=6"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 10 [Chrysochloris asiatica]"
ENSG00000186399(GOLGA8R)	--	0.727571931	51	0.715369955	50	0.525452	42	0.4445809	34	0.566203772	43	0.511004551	39	0.920961075	-0.593733746	normal	0.972846138	-0.231461035	normal	0.980408274	-0.111055914	normal	0.642153934	-0.322910903	normal	--	--	--	--	--	[S]	Function unknown	--	Golgin subfamily A member 8A GN=GOLGA8A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 [Ursus maritimus]
ENSG00000186409(CCDC30)	--	0.22061847	15	0.121545555	8	0.366150216	24	0.371562059	23	0.261715851	17	0.442159738	30	0.980252447	0.540841906	normal	--	--	--	0.98173377	0.296875476	normal	0.503145036	0.555745906	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 30 GN=CCDC30 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 30 [Ursus maritimus]
ENSG00000186416(NKRF)	--	10.905977	797	10.14714	745	11.356619	832	12.436497	888	11.940161	870	11.167072	787	0.970527449	0.12491948	normal	0.953678717	0.201968732	normal	0.973868785	-0.0883462	normal	0.764023799	0.078968149	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	R3H domain;; G-patch domain;; Double-stranded RNA binding motif;; DExH-box splicing factor binding site	NF-kappa-B-repressing factor GN=NKRF OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: NF-kappa-B-repressing factor [Panthera tigris altaica]
ENSG00000186417(GLDN)	--	0.051491641	2	0.013215754	1	0	0	0.01312383	1	0.150115	5	0.030665471	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16364|0|hsa:342035|GLDN, CLOM, COLM, CRG-L2, CRGL2, UNC-112; gliomedin; K16364 GLDN; gliomedin (A)"	--	[W]	Extracellular structures	Olfactomedin-like domain;; Collagen triple helix repeat (20 copies)	Gliomedin GN=GLDN OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: gliomedin [Orcinus orca]
ENSG00000186432(KPNA4)	--	19.78561016	2686	21.0876061	2852	22.62678417	2981	26.98538657	3686	23.91087201	3244	21.36474113	2907	0.724056113	0.425555957	normal	0.983137751	0.164291554	normal	0.989682779	-0.044533867	normal	0.320256706	0.185737021	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein import into nucleus (GO:0006606);; Molecular Function: protein transporter activity (GO:0008565);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Armadillo/beta-catenin-like repeat;; HEAT repeats;; Importin beta binding domain;; HEAT repeat;; HEAT-like repeat;; Adaptin N terminal region;; Armadillo-like;; V-ATPase subunit H;; V-ATPase subunit H	Importin subunit alpha-3 GN=KPNA4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	importin subunit alpha-3 [Bos taurus] 
ENSG00000186446(ZNF501)	--	0.036661462	2	0	0	0	0	0	0	0	0	0.018226758	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain"	Zinc finger protein 501 GN=ZNF501 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 501 isoform X1 [Mustela putorius furo] 
ENSG00000186451(SPATA12)	--	0.233421	11	0.190546	9	0.167966	7	0.149598	7	0.145146	6	0.274482	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Spermatogenesis-associated protein 12 GN=SPATA12 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: spermatogenesis-associated protein 12, partial [Galeopterus variegatus]"
ENSG00000186453(FAM228A)	--	0.0306484	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM228A GN=FAM228A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM228A [Tupaia chinensis]
ENSG00000186462(NAP1L2)	--	4.06312	172	4.73999	204	4.36675	184	2.51933	108	2.88203	121	2.17385	92	0.248324207	-0.694307097	normal	0.075064794	-0.767513675	normal	0.003704429	-0.99647749	normal	0.005109475	-0.824471693	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K11280|0|hsa:4674|NAP1L2, BPX; nucleosome assembly protein 1-like 2; K11280 nucleosome assembly protein 1-like 2 (A)"	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Nucleosome assembly protein (NAP)	Nucleosome assembly protein 1-like 2 GN=NAP1L2 OS=Homo sapiens (Human) PE=1 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nucleosome assembly protein 1-like 2 [Tupaia chinensis] 
ENSG00000186468(RPS23)	--	1455.019062	9498	1372.118466	9384	1427.192984	9642	1646.537264	11944	1541.42107	10760	1397.132092	9979	0.976671963	0.299714835	normal	0.99269396	0.175950106	normal	0.996042311	0.041265016	normal	0.411806356	0.174659451	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02973|1.99077e-99|umr:103681485|RPS23; ribosomal protein S23; K02973 small subunit ribosomal protein S23e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S12/S23	40S ribosomal protein S23 GN=RPS23 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S23 [Felis catus]
ENSG00000186469(GNG2)	--	4.378301391	159	4.518175022	171	4.358539973	187	7.715041043	281	8.314321638	366	5.235037	211	0.021890048	0.7849351	normal	2.55E-05	1.069804792	up	0.955561309	0.164659014	normal	0.060173328	0.709303528	normal	--	--	Molecular Function: signal transducer activity (GO:0004871);; Cellular Component: heterotrimeric G-protein complex (GO:0005834);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; 	"K07826|4.68789e-46|myd:102771107|GNG2; guanine nucleotide binding protein (G protein), gamma 2; K07826 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (A)"	Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	[T]	Signal transduction mechanisms	GGL domain	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 (Precursor) GN=GNG2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 [Equus przewalskii]
ENSG00000186471(AKAP14)	--	0	0	0	0	0	0	0.0667807	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16530|2.36878e-146|ptr:736819|AKAP14; A kinase (PRKA) anchor protein 14; K16530 A-kinase anchor protein 14 (A)	--	--	--	28 kDa A-kinase anchor	A-kinase anchor protein 14 GN=AKAP14 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: A-kinase anchor protein 14 [Sus scrofa]
ENSG00000186472(PCLO)	--	1.14789739	316	0.777204971	279	0.878553239	311	0.947888201	361	0.963940249	304	1.573644637	499	0.955192803	0.16051149	normal	0.962018568	0.101850665	normal	0.03959858	0.671233716	normal	0.385602406	0.341354091	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: synapse (GO:0045202);; Molecular Function: metal ion binding (GO:0046872);; 	K16882|0|ptr:463505|PCLO; piccolo presynaptic cytomatrix protein; K16882 protein piccolo (A)	Insulin secretion (ko04911)	--	--	Piccolo Zn-finger;; C2 domain;; PDZ domain (Also known as DHR or GLGF)	Protein piccolo OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: protein piccolo [Ceratotherium simum simum]
ENSG00000186480(INSIG1)	--	41.09321436	1451	52.0504096	2060	45.98414267	1766	33.58445259	1271	37.072556	1343	93.534933	3608	0.957642897	-0.221664726	normal	0.029483923	-0.638026768	normal	9.75E-08	1.021797512	up	0.867909997	0.219590225	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Insulin-induced protein (INSIG)	Insulin-induced gene 1 protein GN=INSIG1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: insulin-induced gene 1 protein [Equus caballus] 
ENSG00000186493(C5orf38)	--	0.488902813	2	0	0	0.072831528	0	4.093984202	33	5.777008805	49	5.002690728	40	0.000117001	3.2643016	up	1.29E-10	5.051474781	up	1.96E-08	4.774744338	up	3.97E-13	5.908178246	up	--	--	--	--	--	--	--	--	Protein CEI (Precursor) GN=C5orf38 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein CEI [Galeopterus variegatus]
ENSG00000186496(ZNF396)	--	0.701427996	28	0.367818283	15	1.307017371	46	0.485684019	23	0.93937479	37	1.085888024	30	0.983132228	-0.296634736	normal	0.586154639	1.201754248	normal	0.93138247	-0.600346706	normal	1	-0.002607261	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09230|0|ptr:455374|ZNF396; zinc finger protein 396; K09230 SCAN domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"SCAN domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 396 GN=ZNF396 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 396 [Galeopterus variegatus]
ENSG00000186501(TMEM222)	--	16.57792058	411	21.453837	553	17.08206402	433	21.891	556	22.5856756	555	21.60002219	544	0.723248767	0.403812139	normal	0.972039114	-0.016174116	normal	0.871596188	0.319949197	normal	0.338749808	0.223000379	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF778)	Transmembrane protein 222 GN=TMEM222 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 222 [Orycteropus afer afer]
ENSG00000186510(CLCNKA)	--	0.031471397	1	0.04668146	2	0	0	0	0	0.046113388	1	0.122271358	5	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05017|0|hsa:1187|CLCNKA, CLCK1, ClC-K1, hClC-Ka; chloride channel, voltage-sensitive Ka; K05017 chloride channel Ka (A)"	--	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	Chloride channel protein ClC-Ka GN=CLCNKA OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: chloride channel protein ClC-Kb isoform X1 [Panthera tigris altaica]
ENSG00000186517(ARHGAP30)	--	0.38287274	36	0.214721926	19	0.22352259	21	0.190017289	18	0.093347288	6	0.080980592	7	0.825701249	-0.971112068	normal	--	--	--	0.830667018	-1.410370345	normal	--	--	--	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	--	--	RhoGAP domain	Rho GTPase-activating protein 30 GN=ARHGAP30 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 30 isoform X1 [Galeopterus variegatus]
ENSG00000186522(SEPT10)	--	31.40758834	1807	35.5519321	1642	26.057732	1481	19.6329239	1207	18.20089562	1099	15.126629	949	0.043918957	-0.612361245	normal	0.068727242	-0.600008967	normal	0.020067497	-0.649547497	normal	1.99E-05	-0.621075865	normal	--	--	Molecular Function: GTP binding (GO:0005525);; 	K16940|0|mcf:101926106|uncharacterized LOC101926106; K16940 septin 10 (A)	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Septin	Septin-10 GN=SEPT10 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: septin-10 isoform X1 [Mustela putorius furo]
ENSG00000186523(FAM86B1)	--	3.262324091	107	1.643008897	72	2.377785227	70	1.318389354	54	1.770906149	56	1.739912978	65	0.052918031	-0.996859976	normal	0.944716443	-0.375039658	normal	0.97321133	-0.112679773	normal	0.262997853	-0.529761076	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[R]	General function prediction only	Family of unknown function;; Putative methyltransferase	Putative protein N-methyltransferase FAM86B2 {ECO:0000305} GN=FAM86B2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM86A isoform X1 [Galeopterus variegatus]
ENSG00000186526(CYP4F8)	--	1.075613889	88	1.782015262	148	0.96888421	79	0.567418143	47	0.869469825	72	1.5678461	129	0.235422653	-0.913485907	normal	0.005933615	-1.04530453	down	0.441877107	0.688739216	normal	0.703841997	-0.364049135	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17728|0|hsa:11283|CYP4F8, CPF8, CYPIVF8; cytochrome P450, family 4, subfamily F, polypeptide 8 (EC:1.14.14.1); K17728 cytochrome P450, family 4, subfamily F, polypeptide 8 [EC:1.14.14.1] (A)"	Arachidonic acid metabolism (ko00590)	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 4F8 GN=CYP4F8 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: leukotriene-B(4) omega-hydroxylase 1-like [Ceratotherium simum simum]
ENSG00000186532(SMYD4)	--	8.6390218	745	8.137223352	732	8.4461386	732	7.581475003	680	7.257517797	628	6.630026	590	0.962065309	-0.162187662	normal	0.934997341	-0.241965329	normal	0.873341991	-0.318685291	normal	0.240112277	-0.240550325	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[B]	Chromatin structure and dynamics	"SET domain;; TPR repeat;; Tetratricopeptide repeat;; MYND finger;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat"	SET and MYND domain-containing protein 4 GN=SMYD4 OS=Homo sapiens (Human) PE=2 SV=3	B	Chromatin structure and dynamics	PREDICTED: SET and MYND domain-containing protein 4 [Galeopterus variegatus]
ENSG00000186564(FOXD2)	--	0.520463	39	0.648324	50	0.227956	17	0.641513	48	0.163636	12	0.495377	37	0.974541609	0.259500767	normal	0.001575173	-1.950557973	down	0.755547122	1.049045646	normal	0.92498379	-0.152159423	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09397|1.68748e-77|hsa:2306|FOXD2, FKHL17, FREAC-9, FREAC9; forkhead box D2; K09397 forkhead box protein D (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein D2 GN=FOXD2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: forkhead box protein D2 [Condylura cristata]
ENSG00000186566(GPATCH8)	--	10.69131678	1697	11.31722316	1771	10.472306	1648	10.42619944	1615	11.99427962	1888	11.2689612	1731	0.981741777	-0.102189806	normal	0.984256752	0.070809429	normal	0.984128541	0.062542037	normal	0.972791873	0.011878202	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	G-patch domain;; Zinc-finger double-stranded RNA-binding	G patch domain-containing protein 8 GN=GPATCH8 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: G patch domain-containing protein 8 isoform X1 [Physeter catodon]
ENSG00000186575(NF2)	--	9.021253408	1086	10.04096021	1206	12.04187714	1473	13.13874257	1578	10.10444952	1211	8.489129133	1017	0.300913893	0.507641973	normal	0.981203267	-0.015438281	normal	0.179819404	-0.542055494	normal	0.995568656	-0.006498318	normal	--	--	--	"K16684|0|hsa:4771|NF2, ACN, BANF, SCH; neurofibromin 2 (merlin); K16684 merlin (A)"	Hippo signaling pathway (ko04390)	[R]	General function prediction only	Ezrin/radixin/moesin family;; FERM C-terminal PH-like domain;; FERM central domain;; FERM N-terminal domain	Merlin GN=NF2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: merlin isoform X1 [Oryctolagus cuniculus]
ENSG00000186577(C6orf1)	--	19.033249	280	20.44325	344	17.906855	298	18.52392029	279	16.032297	241	19.77524	300	0.966958549	-0.035797189	normal	0.418713628	-0.531992029	normal	0.967864394	0.00135189	normal	0.538480907	-0.190306199	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C6orf1 (Precursor) GN=C6orf1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C6orf1 homolog [Equus caballus]
ENSG00000186583(SPATC1)	--	0.0562833	2	0.0765042	3	0.0829573	2	0.028706	1	0.027402	0	0.0276359	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Speriolin N terminus;; Speriolin C-terminus	Speriolin GN=SPATC1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: speriolin [Ceratotherium simum simum]
ENSG00000186591(UBE2H)	--	60.28277765	3969	54.34034759	3581	57.62932334	3740	70.42704217	5100	74.54571015	4605	63.141787	4309	0.934914396	0.330776217	normal	0.923418317	0.34128469	normal	0.982850351	0.195949513	normal	0.083520282	0.29011565	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10576|2.1888e-106|tup:102487065|UBE2H; ubiquitin-conjugating enzyme E2H; K10576 ubiquitin-conjugating enzyme E2 H [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 H GN=UBE2H OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: ubiquitin-conjugating enzyme E2 H [Sus scrofa]
ENSG00000186603(HPDL)	--	0.437719	11	0.420866	11	0.149114	3	1.16995	30	1.22805	31	0.584815	15	0.685742713	1.3026985	normal	0.5766124	1.358006389	normal	--	--	--	--	--	--	[ER]	Amino acid transport and metabolism;; General function prediction only	--	--	--	[E]	Amino acid transport and metabolism	Glyoxalase-like domain;; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	4-hydroxyphenylpyruvate dioxygenase-like protein GN=HPDL OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: 4-hydroxyphenylpyruvate dioxygenase-like protein [Galeopterus variegatus]
ENSG00000186625(KATNA1)	--	5.386515434	194	4.708374	167	4.431270902	138	5.145638356	184	5.012877082	173	4.871174144	167	0.96282197	-0.106318383	normal	0.96580628	0.02923725	normal	0.937276561	0.2642523	normal	0.929516481	0.048614749	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	K07767|0|ptr:748379|KATNA1; katanin p60 (ATPase containing) subunit A 1; K07767 katanin p60 ATPase-containing subunit A1 [EC:3.6.4.3] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA);; Vps4 C terminal oligomerisation domain;; AAA domain;; AAA domain (Cdc48 subfamily);; Holliday junction DNA helicase ruvB N-terminus	Katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023} OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: katanin p60 ATPase-containing subunit A1 isoform X1 [Condylura cristata]
ENSG00000186628(FSD2)	--	0.388266607	49	0.562351062	71	0.456520566	57	0.363530015	46	0.430038515	54	0.258984926	33	0.978449323	-0.118155428	normal	0.938587293	-0.406329618	normal	0.787921867	-0.769632143	normal	0.463419068	-0.43441032	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Fibronectin type III domain;; SPRY domain	Fibronectin type III and SPRY domain-containing protein 2 GN=FSD2 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: fibronectin type III and SPRY domain-containing protein 2 isoform X2 [Equus caballus] 
ENSG00000186635(ARAP1)	--	35.28497125	2119	40.84225366	2336	36.53722674	2165	28.76452578	1835	32.435659	1951	42.54414886	2475	0.960284673	-0.238249946	normal	0.943400657	-0.28105365	normal	0.976849316	0.184649343	normal	0.705827123	-0.100805924	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K18439|0|hsa:116985|ARAP1, CENTD2; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1; K18439 Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 (A)"	Endocytosis (ko04144)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	RhoGAP domain;; PH domain;; Putative GTPase activating protein for Arf;; Pleckstrin homology domain;; SAM domain (Sterile alpha motif);; Ras association (RalGDS/AF-6) domain;; SAM domain (Sterile alpha motif);; Pleckstrin homology domain;; Pleckstrin homology domain	"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 GN=ARAP1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 [Odobenus rosmarus divergens]"
ENSG00000186638(KIF24)	--	2.624962	361	2.996062046	413	3.066766	420	2.481488	342	2.54490025	352	2.778281636	385	0.963190961	-0.10836085	normal	0.925416831	-0.250996149	normal	0.960998646	-0.133320756	normal	0.559655393	-0.166822225	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10393|0|hsa:347240|KIF24, C9orf48, bA571F15.4; kinesin family member 24; K10393 kinesin family member 2/24 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain;; SAM domain (Sterile alpha motif)	Kinesin-like protein KIF24 GN=KIF24 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF24 [Ceratotherium simum simum]
ENSG00000186642(PDE2A)	--	0.192028529	15	0.1992002	13	0.102990918	7	0.27017034	22	1.321885446	32	0.30637513	14	0.983245498	0.480853171	normal	0.722695303	1.187588695	normal	--	--	--	--	--	--	[T]	Signal transduction mechanisms	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; "	"K18283|0|pps:100989932|PDE2A; phosphodiesterase 2A, cGMP-stimulated; K18283 cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:3.1.4.17] (A)"	Purine metabolism (ko00230);; cGMP-PKG signaling pathway (ko04022);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase;; GAF domain;; GAF domain;; GAF domain	"cGMP-dependent 3',5'-cyclic phosphodiesterase GN=PDE2A OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"cGMP-dependent 3',5'-cyclic phosphodiesterase isoform PDE2A3 [Bos taurus] "
ENSG00000186648(CARMIL3)	--	0.991581473	108	0.504846231	55	0.607579051	67	0.13179499	14	0.06377403	6	0.129539556	14	6.64E-13	-2.846772148	down	3.17E-07	-2.930224779	down	1.25E-05	-2.150747051	down	4.95E-05	-2.7797565	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[N]	Cell motility	Leucine Rich repeat	Leucine-rich repeat-containing protein 16B GN=LRRC16B OS=Homo sapiens (Human) PE=2 SV=2	N	Cell motility	PREDICTED: leucine-rich repeat-containing protein 16B [Ceratotherium simum simum]
ENSG00000186654(PRR5)	--	9.03182991	269	8.686491783	269	11.08367312	333	8.825554894	268	9.679439203	283	7.799589363	237	0.966814396	-0.035999436	normal	0.965327137	0.051487111	normal	0.536435738	-0.496242026	normal	0.613812044	-0.165569964	normal	--	--	--	--	--	--	--	HbrB-like	Proline-rich protein 5 GN=PRR5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: proline-rich protein 5 [Camelus bactrianus]
ENSG00000186660(ZFP91)	--	25.7798	2532	28.0939	2769	26.1002	2547	29.6279	2920	33.4467	3273	31.7065	3119	0.980645448	0.174759894	normal	0.974365919	0.219711517	normal	0.949634316	0.28384061	normal	0.200998164	0.225728151	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	E3 ubiquitin-protein ligase ZFP91 GN=ZFP91 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: ZFP91 zinc finger protein [Elephantulus edwardii]
ENSG00000186665(C17orf58)	--	15.60390721	351	12.97748572	294	13.13806082	326	11.05676455	248	8.499197155	193	9.345432321	221	0.409087742	-0.529191973	normal	0.201588245	-0.624645261	normal	0.319266915	-0.565908149	normal	0.014001084	-0.574235872	normal	--	--	--	--	--	--	--	--	UPF0450 protein C17orf58 GN=C17orf58 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: UPF0450 protein C17orf58 homolog isoform X1 [Mustela putorius furo]
ENSG00000186666(BCDIN3D)	--	6.54248	152	7.61878	160	6.28203	140	6.29541	164	6.3019	168	8.8925	193	0.965662298	0.078032796	normal	0.965417696	0.048515255	normal	0.782320605	0.450719057	normal	0.639329075	0.195085307	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Bicoid-interacting protein 3 (Bin3)	Pre-miRNA 5'-monophosphate methyltransferase GN=BCDIN3D OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: pre-miRNA 5'-monophosphate methyltransferase [Galeopterus variegatus]
ENSG00000186675(MAGEE2)	--	0	0	0	0	0.0471951	1	0	0	0.0233241	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family	Melanoma-associated antigen E2 GN=MAGEE2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: melanoma-associated antigen E2 [Equus przewalskii]
ENSG00000186684(CYP27C1)	--	1.165738428	97	1.226369319	105	1.725363788	107	1.259366474	108	1.624560743	141	1.080498325	82	0.967231476	0.122305935	normal	0.88268143	0.398905669	normal	0.917128192	-0.385956618	normal	0.902758197	0.077615136	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17951|0|hsa:339761|CYP27C1; cytochrome P450, family 27, subfamily C, polypeptide 1; K17951 cytochrome P450, family 27, subfamily C (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 27C1 GN=CYP27C1 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 27C1-like [Tupaia chinensis]
ENSG00000186687(LYRM7)	--	7.657429	423	3.91569	379	5.606065	504	4.563036	453	3.383197	329	3.419024	365	0.968371529	0.067783196	normal	0.936863756	-0.224574094	normal	0.52425984	-0.472146527	normal	0.479211487	-0.208837012	normal	--	--	--	K18170|1.60465e-70|ptr:462041|LYRM7; LYR motif containing 7; K18170 complex III assembly factor LYRM7 (A)	--	--	--	Complex 1 protein (LYR family);; Complex1_LYR-like	Complex III assembly factor LYRM7 GN=LYRM7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: complex III assembly factor LYRM7 isoform X1 [Oryctolagus cuniculus]
ENSG00000186710(CFAP73)	--	0	0	0	0	0.0444258	0	0.234836	5	0.0460059	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4200)	Coiled-coil domain-containing protein 42B GN=CCDC42B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 42B isoform X3 [Bubalus bubalis]
ENSG00000186714(CCDC73)	--	0.62315	24	0.8667044	34	0.421819	15	1.0746856	40	0.5000263	20	0.721238	28	0.932986557	0.672484972	normal	0.92926411	-0.74337463	normal	0.940476664	0.830076428	normal	0.789634621	0.245818734	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 73 GN=CCDC73 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 73 [Trichechus manatus latirostris]
ENSG00000186716(BCR)	--	9.478760787	1257	8.957427895	1171	9.587438938	1311	9.106119447	1281	9.959944106	1340	10.19462756	1321	0.982244656	-0.003542149	normal	0.968706947	0.172856563	normal	0.982690121	0.002668273	normal	0.833604957	0.055352292	normal	--	--	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	"K08878|0|hsa:613|BCR, ALL, BCR1, CML, D22S11, D22S662, PHL; breakpoint cluster region (EC:2.7.11.1); K08878 breakpoint cluster region protein [EC:2.7.11.1] (A)"	Pathways in cancer (ko05200);; Chronic myeloid leukemia (ko05220)	[T]	Signal transduction mechanisms	RhoGAP domain;; Bcr-Abl oncoprotein oligomerisation domain;; RhoGEF domain;; C2 domain;; PH domain	Breakpoint cluster region protein GN=BCR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: breakpoint cluster region protein isoform X1 [Felis catus]
ENSG00000186732(MPPED1)	--	0.023414063	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: hydrolase activity (GO:0016787);; 	--	--	[R]	General function prediction only	Calcineurin-like phosphoesterase;; Calcineurin-like phosphoesterase superfamily domain	Metallophosphoesterase domain-containing protein 1 GN=MPPED1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: metallophosphoesterase domain-containing protein 1 [Chrysochloris asiatica]
ENSG00000186765(FSCN2)	--	2.705043	246	2.196526	260	2.182687	208	2.71848	237	2.68669	233	3.35131	311	0.964154822	-0.084068518	normal	0.950528618	-0.178510738	normal	0.329390568	0.568636599	normal	0.780439538	0.108653167	normal	--	--	"Molecular Function: protein binding, bridging (GO:0030674);; Molecular Function: actin filament binding (GO:0051015);; "	"K17455|0|hsa:25794|FSCN2, RFSN, RP30; fascin actin-bundling protein 2, retinal; K17455 fascin 1/2 (A)"	--	--	--	Fascin domain;; FRG1-like family;; Fibroblast growth factor	Fascin-2 GN=FSCN2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: fascin-2 isoform X1 [Bubalus bubalis]
ENSG00000186766(FOXI2)	--	0.0143428	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09401|2.75351e-131|hsa:399823|FOXI2; forkhead box I2; K09401 forkhead box protein I (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein I2 GN=FOXI2 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	forkhead box protein I2 [Bos taurus] 
ENSG00000186767(SPIN4)	--	8.50949	439	9.75031	502	9.87214	499	7.52501	391	6.11594	315	8.32546	430	0.947238412	-0.197152913	normal	0.02974584	-0.691108668	normal	0.939561628	-0.222268232	normal	0.093180983	-0.363022668	normal	--	--	Biological Process: gamete generation (GO:0007276);; 	--	--	--	--	Spin/Ssty Family	Spindlin-4 GN=SPIN4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: spindlin-4 [Oryctolagus cuniculus]
ENSG00000186787(SPIN2B)	--	4.210932031	78	3.451299998	63	3.38665873	74	3.425236674	70	2.66144963	46	3.194962579	54	0.968323551	-0.183140959	normal	0.933502017	-0.462107734	normal	0.925341654	-0.451999749	normal	0.52279442	-0.36085876	normal	--	--	Biological Process: gamete generation (GO:0007276);; 	--	--	--	--	Spin/Ssty Family	Spindlin-2B GN=SPIN2B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: spindlin-2B-like isoform 1 [Dasypus novemcinctus]
ENSG00000186790(FOXE3)	--	0	0	0	0	0	0	0	0	0.115639	2	0.0393807	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09398|1.85427e-97|hsa:2301|FOXE3, FKHL12, FREAC8; forkhead box E3; K09398 forkhead box protein E (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein E3 GN=FOXE3 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: forkhead box protein E3 [Orcinus orca]
ENSG00000186792(HYAL3)	--	42.38388568	1436	42.53010086	1454	49.13218464	1678	47.88218281	1619	45.25803956	1553	38.11501845	1331	0.976840516	0.142071759	normal	0.981964619	0.073529997	normal	0.866043665	-0.342176518	normal	0.878949981	-0.042149865	normal	--	--	Molecular Function: hyalurononglucosaminidase activity (GO:0004415);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K01197|0|hsa:8372|HYAL3, HYAL-3, LUCA-3, LUCA3; hyaluronoglucosaminidase 3 (EC:3.2.1.35); K01197 hyaluronoglucosaminidase [EC:3.2.1.35] (A)"	Glycosaminoglycan degradation (ko00531)	--	--	Hyaluronidase	Hyaluronidase-3 (Precursor) GN=HYAL3 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: hyaluronidase-3 isoform X1 [Physeter catodon]
ENSG00000186806(VSIG10L)	--	10.788829	409	8.495666	323	8.428566	323	6.133979675	234	8.002893	296	5.637229	224	0.002436755	-0.832233913	normal	0.956454265	-0.146646028	normal	0.426040145	-0.533311381	normal	0.027355738	-0.505947523	normal	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain	V-set and immunoglobulin domain-containing protein 10-like (Precursor) GN=VSIG10L OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: V-set and immunoglobulin domain-containing protein 10-like [Odobenus rosmarus divergens]
ENSG00000186812(ZNF397)	--	7.660524931	479	9.319833596	509	6.260982562	457	4.883523711	344	5.736157003	403	7.067230476	488	0.407335847	-0.506522353	normal	0.824665419	-0.357116928	normal	0.967849549	0.086119716	normal	0.296765479	-0.246840841	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:84307|ZNF397, ZNF47, ZSCAN15; zinc finger protein 397; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; Prokaryotic RING finger family 1;; Transposase zinc-ribbon domain"	Zinc finger protein 397 GN=ZNF397 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 397 [Equus caballus]
ENSG00000186814(ZSCAN30)	--	3.456389423	198	3.065444025	175	3.388799777	184	2.531874364	153	3.357813528	195	2.582470702	164	0.842504484	-0.399265382	normal	0.958912848	0.133598577	normal	0.955465468	-0.172796188	normal	0.739402947	-0.142412835	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:100101467|ZSCAN30, ZNF-WYM, ZNF397OS, ZNF917; zinc finger and SCAN domain containing 30; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and SCAN domain-containing protein 30 GN=ZSCAN30 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 30 [Galeopterus variegatus]
ENSG00000186815(TPCN1)	--	29.06218821	2552	26.2598495	2358	23.5988335	2330	27.94656032	2639	30.66867339	2841	30.91258677	2870	0.989055272	0.017520385	normal	0.963810808	0.247263909	normal	0.941786593	0.292258132	normal	0.323579562	0.184795144	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K16896|0|hsa:53373|TPCN1, TPC1; two pore segment channel 1; K16896 two pore calcium channel protein 1 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein	Two pore calcium channel protein 1 GN=TPCN1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: two pore calcium channel protein 1 isoform X2 [Mustela putorius furo]
ENSG00000186832(KRT16)	--	0.224718492	7	0.217237013	7	0.301827498	9	0.502317719	16	0.457797125	14	0.145509353	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:3868|KRT16, CK16, FNEPPK, K16, K1CP, KRT16A, NEPPK, PC1; keratin 16; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 16 GN=KRT16 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 16 [Mustela putorius furo] "
ENSG00000186834(HEXIM1)	--	54.2521	3432	52.886	3422	54.2694	3489	46.4191	2981	49.6522	3135	46.7559	2977	0.972025831	-0.233972932	normal	0.985549999	-0.147732636	normal	0.971323798	-0.23713442	normal	0.253347606	-0.206956638	normal	--	--	Biological Process: negative regulation of transcription from RNA polymerase II promoter (GO:0000122);; Molecular Function: cyclin-dependent protein serine/threonine kinase inhibitor activity (GO:0004861);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Molecular Function: snRNA binding (GO:0017069);; 	K15189|1.55488e-170|nle:100601526|HEXIM1; hexamethylene bis-acetamide inducible 1; K15189 protein HEXIM1/2 (A)	--	--	--	Hexamethylene bis-acetamide-inducible protein	Protein HEXIM1 GN=HEXIM1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein HEXIM1 [Galeopterus variegatus]
ENSG00000186838(SELENOV)	--	0.0362748	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Selenoprotein V GN=SELV OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: selenoprotein V [Camelus bactrianus] 
ENSG00000186854(TRABD2A)	--	4.058453	207	2.536088313	151	3.057489352	166	2.627689784	150	2.818642	156	1.732768912	120	0.686676889	-0.491197024	normal	0.966266944	0.025321424	normal	0.782741287	-0.471367133	normal	0.380481901	-0.320535897	normal	--	--	--	--	--	--	--	TraB family	Metalloprotease TIKI1 (Precursor) GN=TRABD2A OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: metalloprotease TIKI1 isoform X1 [Felis catus]
ENSG00000186862(PDZD7)	--	1.18358	58	0.524331	23	1.092145	41	1.208095	34	1.093406	42	0.56228325	24	0.77424608	-0.774241155	normal	0.86744947	0.807524501	normal	0.90300236	-0.74458584	normal	0.726846246	-0.308585796	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	PDZ domain (Also known as DHR or GLGF);; PDZ domain	PDZ domain-containing protein 7 GN=PDZD7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: PDZ domain-containing protein 7 [Galeopterus variegatus]
ENSG00000186866(POFUT2)	--	9.830886254	612	8.735582297	542	8.868966691	546	7.999948	503	10.04183289	613	8.519053825	538	0.878265381	-0.312937255	normal	0.960017074	0.155758821	normal	0.972289659	-0.029503895	normal	0.84625189	-0.060554607	normal	--	--	--	K03691|0|ggo:101147854|POFUT2; GDP-fucose protein O-fucosyltransferase 2; K03691 peptide-O-fucosyltransferase [EC:2.4.1.221] (A)	Other types of O-glycan biosynthesis (ko00514)	--	--	GDP-fucose protein O-fucosyltransferase	GDP-fucose protein O-fucosyltransferase 2 (Precursor) GN=POFUT2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: GDP-fucose protein O-fucosyltransferase 2 [Orycteropus afer afer]
ENSG00000186867(QRFPR)	--	0.039229	1	0	0	0.229232	5	0.117319606	3	0.380669297	9	0.1802298	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08378|0|hsa:84109|QRFPR, AQ27, GPR103, SP9155; pyroglutamylated RFamide peptide receptor; K08378 G protein-coupled receptor 103 (A)"	--	--	--	7 transmembrane receptor (rhodopsin family)	Pyroglutamylated RFamide peptide receptor GN=QRFPR OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: pyroglutamylated RFamide peptide receptor [Equus caballus] 
ENSG00000186868(MAPT)	--	2.572550573	262	1.663250431	125	1.302472782	142	0.852341787	90	1.801467477	160	0.974660073	81	1.56E-09	-1.556067613	down	0.911679548	0.331168222	normal	0.138565281	-0.806665149	normal	0.382740299	-0.697893821	normal	--	--	Molecular Function: tubulin binding (GO:0015631);; 	"K04380|0|hsa:4137|MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, PPP1R103, TAU; microtubule-associated protein tau; K04380 microtubule-associated protein tau (A)"	MAPK signaling pathway (ko04010);; Alzheimer's disease (ko05010)	[Z]	Cytoskeleton	"Tau and MAP protein, tubulin-binding repeat"	Microtubule-associated protein tau GN=MAPT OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: microtubule-associated protein tau isoform 1 [Ceratotherium simum simum]
ENSG00000186871(ERCC6L)	--	7.925648	657	8.87908	733	10.17521619	827	8.396473	701	6.698784	553	5.918343	490	0.97335256	0.062547197	normal	0.650329104	-0.426942478	normal	0.00235113	-0.761566729	normal	0.110123669	-0.368241064	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	--	--	--	--	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase;; Class II histone deacetylase complex subunits 2 and 3"	DNA excision repair protein ERCC-6-like GN=ERCC6L OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA excision repair protein ERCC-6-like [Ceratotherium simum simum]
ENSG00000186889(TMEM17)	--	4.56719	119	3.85174	102	4.71066	123	2.97131	79	3.40343	88	3.71455	97	0.653775704	-0.612097197	normal	0.95599292	-0.230733436	normal	0.922935091	-0.346089977	normal	0.349418643	-0.402204122	normal	--	--	--	--	--	[S]	Function unknown	Predicted membrane protein	Transmembrane protein 17 GN=TMEM17 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 17 isoform X1 [Oryctolagus cuniculus]
ENSG00000186897(C1QL4)	--	7.89176	281	3.50413	130	6.09896	230	2.86885	104	3.29208	117	1.9844	72	9.88E-09	-1.4512194	down	0.95864582	-0.171327611	normal	7.38E-10	-1.66321051	down	0.043442597	-1.151108284	normal	--	--	--	--	--	--	--	C1q domain	Complement C1q-like protein 4 (Precursor) GN=C1QL4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"PREDICTED: complement component 1, q subcomponent-like 4 [Canis lupus familiaris] "
ENSG00000186907(RTN4RL2)	--	10.17113363	330	5.846307228	191	8.010508652	250	7.521299916	244	11.56611622	329	13.2518599	438	0.631540346	-0.463894596	normal	0.023568634	0.758459988	normal	0.004451016	0.797022363	normal	0.519654517	0.371576261	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K16661|0|hsa:349667|RTN4RL2, NGRH1, NgR2; reticulon 4 receptor-like 2; K16661 reticulon-4 receptor-like 2 (A)"	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies)	Reticulon-4 receptor-like 2 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: reticulon-4 receptor-like 2 [Dasypus novemcinctus]
ENSG00000186908(ZDHHC17)	--	7.250918	564	8.725275695	687	7.57951385	588	7.9663791	625	9.2550635	720	8.36615431	651	0.966990609	0.117025847	normal	0.973999012	0.04616099	normal	0.964660024	0.138211986	normal	0.7214522	0.09703482	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K18932|0|tup:102469219|ZDHHC17; zinc finger, DHHC-type containing 17; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; DHHC palmitoyltransferase;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Palmitoyltransferase ZDHHC17 GN=ZDHHC17 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC17 [Tupaia chinensis]
ENSG00000186912(P2RY4)	--	0.0453835	1	0.0446598	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04271|0|hsa:5030|P2RY4, NRU, P2P, P2Y4, UNR; pyrimidinergic receptor P2Y, G-protein coupled, 4; K04271 pyrimidinergic receptor P2Y, G protein-coupled, 4 (A)"	Neuroactive ligand-receptor interaction (ko04080)	--	--	7 transmembrane receptor (rhodopsin family)	P2Y purinoceptor 4 GN=P2RY4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	P2Y purinoceptor 4 [Sus scrofa]
ENSG00000186918(ZNF395)	--	11.322555	825	12.7335853	992	11.11298177	785	12.65241577	947	8.827275881	687	11.01819123	849	0.96417796	0.167846128	normal	0.186018127	-0.550442127	normal	0.972532657	0.104586675	normal	0.791434481	-0.089505228	normal	--	--	--	--	--	--	--	--	Zinc finger protein 395 GN=ZNF395 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 395 [Chrysochloris asiatica]
ENSG00000186951(PPARA)	--	1.711379712	212	1.348758778	185	1.844223194	149	1.050135593	168	2.000205585	263	1.676174271	174	0.870592813	-0.363468455	normal	0.647560375	0.482785615	normal	0.949031983	0.213476698	normal	0.823164267	0.126712019	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K07294|0|hsa:5465|PPARA, NR1C1, PPAR, PPARalpha, hPPAR; peroxisome proliferator-activated receptor alpha; K07294 peroxisome proliferator-activated receptor alpha (A)"	PPAR signaling pathway (ko03320);; cAMP signaling pathway (ko04024);; Adipocytokine signaling pathway (ko04920);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	"Zinc finger, C4 type (two domains);; Ligand-binding domain of nuclear hormone receptor"	Peroxisome proliferator-activated receptor alpha GN=PPARA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: peroxisome proliferator-activated receptor alpha [Galeopterus variegatus]
ENSG00000186952(TMEM232)	--	0.06410658	3	0.06411302	3	0	0	0	0	0	0	0.0240279	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 232 GN=TMEM232 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: transmembrane protein 232, partial [Odobenus rosmarus divergens]"
ENSG00000186973(FAM183A)	--	0.408873996	2	0.401759	2	0.19352296	0	0.369764	2	0.595169212	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM183A and FAM183B related	Protein FAM183A GN=FAM183A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM183A [Equus caballus]
ENSG00000186976(EFCAB6)	--	0.242659582	14	0.186304459	6	0.406013096	12	0.06709983	7	0.197612584	16	0.181128837	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF1880);; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair;; EF hand	EF-hand calcium-binding domain-containing protein 6 GN=EFCAB6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: EF-hand calcium-binding domain-containing protein 6 [Ceratotherium simum simum]
ENSG00000186994(KANK3)	--	2.0590215	90	2.219960095	84	2.481968	111	1.81677384	77	1.7549516	75	1.941317404	76	0.958549652	-0.251255804	normal	0.965310945	-0.18146563	normal	0.788973112	-0.545740463	normal	0.488941	-0.342697249	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Putative binding domain;; Ankyrin repeats (many copies);; KN motif;; Ankyrin repeat	KN motif and ankyrin repeat domain-containing protein 3 GN=KANK3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: KN motif and ankyrin repeat domain-containing protein 3 [Oryctolagus cuniculus] 
ENSG00000186998(EMID1)	--	0.35867751	15	0.398381292	16	0.260081334	10	0.311025594	13	0.555936544	14	0.19163573	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Collagen triple helix repeat (20 copies);; EMI domain	EMI domain-containing protein 1 (Precursor) GN=EMID1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: EMI domain-containing protein 1 isoform X4 [Sus scrofa]
ENSG00000187010(RHD)	--	0.072929734	3	0.024093946	1	0.047900568	1	0.051713815	1	0.141453	5	0.0723777	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; 	"K06579|0|mcf:102136135|RHCE; Rh blood group, CcEe antigens; K06579 Rhesus blood group glycoprotein (A)"	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Ammonium Transporter Family	Blood group Rh(D) polypeptide GN=RHD OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: RH-like protein [Eptesicus fuscus]
ENSG00000187017(ESPN)	--	0.2045201	3	0	0	0	0	0.1904328	2	0.1222861	1	0.077515716	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: actin binding (GO:0003779);; Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; WH2 motif	Espin GN=ESPN OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: espin isoform X2 [Canis lupus familiaris]
ENSG00000187024(PTRH1)	--	10.59718611	128	9.567107	127	9.250444	126	11.619007	139	10.0606807	130	8.288235	102	0.966394865	0.087105348	normal	0.967433565	0.012113995	normal	0.934358442	-0.309015947	normal	0.924076483	-0.060452084	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: aminoacyl-tRNA hydrolase activity (GO:0004045);; 	"K01056|6.64433e-124|pps:100992564|PTRH1; peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae); K01056 peptidyl-tRNA hydrolase, PTH1 family [EC:3.1.1.29] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Peptidyl-tRNA hydrolase	Probable peptidyl-tRNA hydrolase GN=PTRH1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: probable peptidyl-tRNA hydrolase [Ceratotherium simum simum]
ENSG00000187045(TMPRSS6)	--	0.217655573	13	0.129861238	8	0.143478424	8	0.199984253	12	0.097679767	5	0.14925469	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; 	"K09637|0|hsa:164656|TMPRSS6, IRIDA; transmembrane protease, serine 6; K09637 transmembrane protease, serine 6 [EC:3.4.21.-] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Low-density lipoprotein receptor domain class A;; SEA domain;; Domain of unknown function (DUF1986);; CUB domain	Transmembrane protease serine 6 GN=TMPRSS6 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: transmembrane protease serine 6 [Camelus ferus] 
ENSG00000187049(TMEM216)	--	6.202285	107	7.88141	137	9.591262	162	8.77905	145	10.07811	173	11.315396	193	0.88018059	0.402627449	normal	0.916457557	0.312097899	normal	0.939928559	0.242241371	normal	0.407341821	0.312013971	normal	--	--	--	--	--	[S]	Function unknown	Predicted membrane protein	Transmembrane protein 216 GN=TMEM216 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: transmembrane protein 216 isoform X1 [Oryctolagus cuniculus]
ENSG00000187051(RPS19BP1)	--	37.11694	600	40.729019	678	41.88201	704	43.89321088	741	44.50884086	724	50.171744	823	0.915793968	0.273048684	normal	0.972547225	0.073120024	normal	0.94805883	0.216594832	normal	0.395358978	0.186387464	normal	--	--	--	--	--	--	--	--	Active regulator of SIRT1 GN=RPS19BP1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: active regulator of SIRT1 [Ailuropoda melanoleuca] 
ENSG00000187066(TMEM262)	--	0.572336	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 262 GN=TMEM262 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: putative uncharacterized protein FLJ42147 isoform X1 [Oryctolagus cuniculus]
ENSG00000187068(C3orf70)	--	0	0	0.0104716	1	0.0104226	0	0.0104878	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	UPF0524 protein C3orf70 GN=C3orf70 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0524 protein C3orf70 homolog [Camelus bactrianus] 
ENSG00000187079(TEAD1)	--	51.58722312	7460	60.55158171	8202	69.74416027	8709	49.96625835	6263	48.53863141	5878	58.5784714	6705	0.973056271	-0.283090282	normal	0.531349756	-0.501967064	normal	0.902880511	-0.385484667	normal	0.017317064	-0.391750444	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09448|0|hsa:7003|TEAD1, AA, NTEF-1, REF1, TCF-13, TCF13, TEAD-1, TEF-1; TEA domain family member 1 (SV40 transcriptional enhancer factor); K09448 transcriptional enhancer factor (A)"	Hippo signaling pathway (ko04390)	[K]	Transcription	TEA/ATTS domain family	Transcriptional enhancer factor TEF-1 GN=TEAD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcriptional enhancer factor TEF-1 isoform X6 [Bison bison bison]
ENSG00000187091(PLCD1)	--	3.057078321	186	2.088377464	129	2.3316052	144	2.083435076	126	2.955702329	179	1.44633415	90	0.487961206	-0.586781545	normal	0.802300353	0.446698729	normal	0.396003166	-0.67728345	normal	0.685055732	-0.238472948	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: calcium ion binding (GO:0005509);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05857|0|hsa:5333|PLCD1, NDNC3, PLC-III; phospholipase C, delta 1 (EC:3.1.4.11); K05857 phosphatidylinositol phospholipase C, delta [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; Calcium signaling pathway (ko04020);; Phosphatidylinositol signaling system (ko04070);; Thyroid hormone signaling pathway (ko04919)	[T]	Signal transduction mechanisms	"Phosphatidylinositol-specific phospholipase C, X domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; EF hand;; Phosphoinositide-specific phospholipase C, efhand-like;; C2 domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 GN=PLCD1 OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1 [Mustela putorius furo] "
ENSG00000187094(CCK)	--	4.071184445	46	1.462893011	17	4.196674534	49	1.720041147	20	1.448672365	16	0.868889197	10	0.397927501	-1.171487153	normal	--	--	--	0.000502787	-2.141082573	down	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; 	K05226|5.0708e-79|hsa:885|CCK; cholecystokinin; K05226 cholecystokinin (A)	--	--	--	Gastrin/cholecystokinin family	Cholecystokinin-5 (Precursor) GN=CCK OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: cholecystokinin [Galeopterus variegatus]
ENSG00000187097(ENTPD5)	--	6.228394	484	5.2106863	462	6.035777402	464	5.36867	454	4.976608702	423	5.6299901	495	0.963687912	-0.122744589	normal	0.958493011	-0.148154711	normal	0.968108294	0.084744825	normal	0.857944869	-0.060405828	normal	[GO]	"Carbohydrate transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Molecular Function: hydrolase activity (GO:0016787);; 	"K01511|0|hsa:957|ENTPD5, CD39L4, NTPDase-5, PCPH; ectonucleoside triphosphate diphosphohydrolase 5 (EC:3.6.1.6 3.6.1.42); K01511 ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	GDA1/CD39 (nucleoside phosphatase) family	Ectonucleoside triphosphate diphosphohydrolase 5 (Precursor) GN=ENTPD5 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: ectonucleoside triphosphate diphosphohydrolase 5 isoformX1 [Canis lupus familiaris] 
ENSG00000187098(MITF)	--	8.574349937	592	7.362313702	548	9.624462426	683	15.99699833	1088	14.16895204	864	16.83977538	1167	0.000164686	0.845535275	normal	0.046564751	0.634024202	normal	0.001410344	0.763247642	normal	0.000208572	0.754038486	normal	--	--	"Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	K09455|0|mcf:102121325|MITF; microphthalmia-associated transcription factor; K09455 microphthalmia-associated transcription factor (A)	Osteoclast differentiation (ko04380);; Melanogenesis (ko04916);; Pathways in cancer (ko05200);; Melanoma (ko05218)	[K]	Transcription	Domain of unknown function (DUF3371);; Helix-loop-helix DNA-binding domain	Microphthalmia-associated transcription factor GN=MITF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: microphthalmia-associated transcription factor isoform X1 [Oryctolagus cuniculus]
ENSG00000187105(HEATR4)	--	0.0948165	1	0.0930868	1	0	0	0.357842653	8	0.172006769	4	0.265515407	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	HEAT repeats;; HEAT repeat;; HEAT-like repeat;; PBS lyase HEAT-like repeat	HEAT repeat-containing protein 4 GN=HEATR4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: HEAT repeat-containing protein 4 [Ceratotherium simum simum]
ENSG00000187109(NAP1L1)	--	388.8026314	13741	403.0370464	13826	383.130428	13110	369.7129604	13805	373.0000293	13087	396.3637693	13719	0.997116196	-0.024125684	normal	0.996242147	-0.10066465	normal	0.996843112	0.057209746	normal	0.946424734	-0.023661734	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11279|5.76561e-147|bacu:103003093|NAP1L1; nucleosome assembly protein 1-like 1; K11279 nucleosome assembly protein 1-like 1 (A)	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Nucleosome assembly protein (NAP)	Nucleosome assembly protein 1-like 1 (Precursor) GN=NAP1L1 OS=Homo sapiens (Human) PE=1 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nucleosome assembly protein 1-like 1 isoform X1 [Balaenoptera acutorostrata scammoni] 
ENSG00000187118(CMC1)	--	44.22509	397	55.64805	432	49.25947	428	45.87248	362	45.26367	367	42.45082	332	0.955158302	-0.163319324	normal	0.922977568	-0.255705381	normal	0.80410087	-0.373217535	normal	0.281705856	-0.265935494	normal	--	--	--	K18171|2.62946e-75|pon:100433872|CMC1; C-x(9)-C motif containing 1; K18171 COX assembly mitochondrial protein 1 (A)	--	[S]	Function unknown	Cytochrome c oxidase biogenesis protein Cmc1 like	COX assembly mitochondrial protein homolog GN=CMC1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COX assembly mitochondrial protein homolog [Orcinus orca]
ENSG00000187122(SLIT1)	--	0.07211409	11	0.005961827	1	0.029964179	3	0.097535	5	0.010071434	0	0.041011836	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06838|0|hsa:6585|SLIT1, MEGF4, SLIL1, SLIT-1, SLIT3; slit homolog 1 (Drosophila); K06838 slit 1 (A)"	Axon guidance (ko04360)	[WT]	Extracellular structures;; Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Laminin G domain;; EGF-like domain;; Laminin G domain;; Leucine rich repeat N-terminal domain;; Leucine-rich repeat;; Leucine rich repeat C-terminal domain;; Human growth factor-like EGF	Slit homolog 1 protein (Precursor) GN=SLIT1 OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 19-like isoform 1 [Ceratotherium simum simum]
ENSG00000187123(LYPD6)	--	0.986201269	66	0.856218973	46	0.579231932	38	0.266912242	18	0.348971757	23	0.118764606	8	0.000316734	-1.818766081	down	0.670883736	-0.9752202	normal	0.008986329	-2.061910836	down	0.001698364	-1.637420479	down	--	--	--	--	--	--	--	--	Ly6/PLAUR domain-containing protein 6 (Precursor) GN=LYPD6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ly6/PLAUR domain-containing protein 6-like isoform 1 [Dasypus novemcinctus] 
ENSG00000187134(AKR1C1)	--	27.04088486	1046	22.97850261	1018	30.7197294	1043	51.96324255	2492	63.2697572	3003	121.2662177	5183	4.00E-11	1.22039267	up	0	1.537846382	up	0	2.303094584	up	0.008466431	1.76207917	up	[R]	General function prediction only	--	"K00212|0|hsa:1645|AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB; aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112); K00089 3alpha-hydroxysteroid dehydrogenase (A-specific) [EC:1.1.1.213] K00212 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.20] (A)"	Steroid hormone biosynthesis (ko00140);; Metabolism of xenobiotics by cytochrome P450 (ko00980)	[R]	General function prediction only	Aldo/keto reductase family	Aldo-keto reductase family 1 member C1 GN=AKR1C1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	prostaglandin-E(2) 9-reductase-like [Oryctolagus cuniculus] 
ENSG00000187140(FOXD3)	--	1.20894	36	1.17326	36	0.80818	25	0.925982	28	0.993879	30	1.4267	43	0.975008678	-0.375194896	normal	0.977850004	-0.271929303	normal	0.89677267	0.739628362	normal	0.985435375	0.037784862	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09397|5.56286e-105|cfa:489558|FOXD3; forkhead box D3; K09397 forkhead box protein D (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein D3 GN=FOXD3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein D3 [Ochotona princeps]
ENSG00000187144(SPATA21)	--	0	0	0	0	0	0	0.0478873	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair	Spermatogenesis-associated protein 21 GN=SPATA21 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: spermatogenesis-associated protein 21 [Pteropus alecto] 
ENSG00000187147(RNF220)	--	17.52591897	823	17.09596046	811	16.20464831	775	17.94814658	831	19.64604448	876	21.67322785	916	0.977220788	-0.016844922	normal	0.973701855	0.089641541	normal	0.943478409	0.23244219	normal	0.681326056	0.101806822	normal	--	--	Biological Process: protein ubiquitination (GO:0016567);; Biological Process: positive regulation of canonical Wnt signaling pathway (GO:0090263);; 	--	--	--	--	"Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF220 GN=RNF220 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF220 [Orcinus orca] 
ENSG00000187164(SHTN1)	--	18.3105669	1837	21.08967913	2108	18.48904906	1776	16.29506124	1656	17.09741907	1733	16.34306698	1588	0.973057384	-0.180322271	normal	0.923742941	-0.303788967	normal	0.974384899	-0.169559334	normal	0.209768697	-0.222481686	normal	--	--	--	--	--	--	--	--	Shootin-1 GN=KIAA1598 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: shootin-1 isoform X1 [Pteropus alecto]
ENSG00000187166(H1FNT)	--	0.0407381	1	0	0	0	0	0	0	0.0782917	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testis-specific H1 histone GN=H1FNT OS=Homo sapiens (Human) PE=2 SV=3	B	Chromatin structure and dynamics	"PREDICTED: testis-specific H1 histone, partial [Ursus maritimus]"
ENSG00000187186(RP11-195F19.5)	--	13.76904275	83	9.789918061	61	11.06083501	104	7.070477313	44	10.60776856	38	8.827015	66	0.263116737	-0.922583269	normal	0.831940403	-0.68259578	normal	0.649385244	-0.652328162	normal	0.088900242	-0.763988106	normal	--	--	--	K16598|7.20159e-54|mcc:699778|uncharacterized LOC699778; K16598 C-C motif chemokine 27 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	--	--	S	Function unknown	hypothetical protein PANDA_021059 [Ailuropoda melanoleuca]
ENSG00000187187(ZNF546)	--	1.998525922	171	1.81859398	188	2.318746505	228	1.803006988	161	1.885585276	175	2.233621793	220	0.962649691	-0.116687132	normal	0.960071948	-0.123772057	normal	0.965628593	-0.059420487	normal	0.826877892	-0.098103982	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101135645|ZNF546; zinc finger protein 546; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; NTF2 fold immunity protein;; Zinc ribbon domain;; XPA protein N-terminal;; Transposase zinc-ribbon domain;; CHY zinc finger"	Zinc finger protein 546 GN=ZNF546 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 546 isoform X1 [Galeopterus variegatus]
ENSG00000187189(TSPYL4)	--	2.36469	167	2.43239	173	2.669	188	4.16066	295	4.22053	297	3.25047	230	0.018920161	0.784536851	normal	0.033876224	0.753182243	normal	0.921219154	0.280566094	normal	0.0147594	0.616929443	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K11287|0|hsa:23270|TSPYL4, dJ486I3.2; TSPY-like 4; K11287 TSPY-like 4 (A)"	--	[L]	"Replication, recombination and repair"	Nucleosome assembly protein (NAP)	Testis-specific Y-encoded-like protein 4 GN=TSPYL4 OS=Homo sapiens (Human) PE=2 SV=2	L	"Replication, recombination and repair"	PREDICTED: testis-specific Y-encoded-like protein 4 [Galeopterus variegatus]
ENSG00000187193(MT1X)	--	106.002952	266	74.79742	188	91.49873	240	454.493	1255	496.2026	1250	179.0769	473	0	2.200920149	up	0	2.701981021	up	7.02E-05	0.966096582	normal	0.008269842	2.078107722	up	--	--	--	K14739|1.59566e-08|ptr:100616506|MT1X; metallothionein 1X; K14739 metallothionein 1/2 (A)	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Metallothionein	Metallothionein-1X GN=MT1X OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	hypothetical protein CB1_001402132 [Camelus ferus]
ENSG00000187210(GCNT1)	--	1.840082	162	1.226291011	107	1.687178033	145	0.81926615	72	0.8707241	76	1.0533203	93	0.000363925	-1.183445833	down	0.836041893	-0.506429714	normal	0.484720973	-0.640630163	normal	0.019489818	-0.800804079	normal	--	--	Molecular Function: acetylglucosaminyltransferase activity (GO:0008375);; Cellular Component: membrane (GO:0016020);; 	"K00727|0|hsa:2650|GCNT1, C2GNT, C2GNT-L, C2GNT1, G6NT, NACGT2, NAGCT2; glucosaminyl (N-acetyl) transferase 1, core 2 (EC:2.4.1.102); K00727 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [EC:2.4.1.102] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	Core-2/I-Branching enzyme	"Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase GN=GCNT1 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase [Oryctolagus cuniculus]"
ENSG00000187231(SESTD1)	--	4.069398469	656	3.885759538	621	3.566897348	560	3.720220654	576	4.377330043	705	5.7181376	810	0.943994136	-0.21791409	normal	0.960792261	0.161234736	normal	0.272180011	0.523022794	normal	0.563762602	0.166473468	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Divergent CRAL/TRIO domain;; Spectrin repeat	SEC14 domain and spectrin repeat-containing protein 1 GN=SESTD1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: SEC14 domain and spectrin repeat-containing protein 1 isoform 1 [Canis lupus familiaris] 
ENSG00000187239(FNBP1)	--	7.3753976	699	6.980952987	669	7.990867708	701	7.1757355	650	5.412300415	541	5.618871742	536	0.966063098	-0.135376321	normal	0.8643295	-0.326980487	normal	0.735844289	-0.394496578	normal	0.161402987	-0.282447081	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	"Fes/CIP4, and EFC/F-BAR homology domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Bacterial SH3 domain"	Formin-binding protein 1 GN=FNBP1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: formin-binding protein 1 isoform X1 [Chrysochloris asiatica]
ENSG00000187240(DYNC2H1)	--	3.909709829	702	4.05931736	700	3.141356864	753	3.800553104	944	5.161755477	885	5.985791244	967	0.728484909	0.395734341	normal	0.881045874	0.316287065	normal	0.828612816	0.351949297	normal	0.042048302	0.354659819	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10414|0|hsa:79659|DYNC2H1, ATD3, DHC1b, DHC2, DNCH2, DYH1B, SRPS2B, SRTD3, hdhc11; dynein, cytoplasmic 2, heavy chain 1; K10414 dynein heavy chain 2, cytosolic (A)"	Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; ATP-binding dynein motor region D5;; Dynein heavy chain, N-terminal region 1;; AAA domain (dynein-related subfamily);; P-loop containing dynein motor region D4;; Microtubule-binding stalk of dynein motor;; P-loop containing dynein motor region D3;; AAA domain;; AAA ATPase domain;; Protein of unknown function, DUF258;; AAA domain;; Archaeal ATPase;; ATPase family associated with various cellular activities (AAA)"	Cytoplasmic dynein 2 heavy chain 1 GN=DYNC2H1 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: cytoplasmic dynein 2 heavy chain 1 isoform 1 [Ceratotherium simum simum]
ENSG00000187242(KRT12)	--	0.106753	4	0	0	0.0774828	2	0.0797933	3	0.0519055	1	0.18561	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|ptr:468241|KRT12; keratin 12; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 12 GN=KRT12 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 12 isoform X2 [Galeopterus variegatus]"
ENSG00000187243(MAGED4B)	--	1.522996219	32	1.837121305	40	1.191358961	32	0.913747135	22	1.246060846	25	1.450337198	36	0.967853767	-0.539952536	normal	0.927013337	-0.6673025	normal	0.98193961	0.154735843	normal	0.658860259	-0.345366301	normal	--	--	--	--	--	--	--	MAGE family	Melanoma-associated antigen D4 GN=MAGED4B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: melanoma-associated antigen D4 [Galeopterus variegatus]
ENSG00000187244(BCAM)	--	47.84820465	2713	39.294882	2224	37.227682	2201	25.16810405	1447	37.92643398	2197	20.46747005	1187	2.64E-06	-0.936917041	normal	0.987075015	-0.039021779	normal	1.25E-05	-0.898276569	normal	0.080699865	-0.584762049	normal	--	--	--	K06578|0|ptr:744276|BCAM; basal cell adhesion molecule (Lutheran blood group); K06578 Lutheran blood group glycoprotein (A)	--	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Basal cell adhesion molecule (Precursor) GN=BCAM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: basal cell adhesion molecule, partial [Balaenoptera acutorostrata scammoni]"
ENSG00000187257(RSBN1L)	--	6.814566192	539	5.960275385	507	10.47603198	662	6.132954353	483	6.519269011	520	8.015133057	506	0.951447672	-0.18852626	normal	0.971230384	0.015054978	normal	0.736535016	-0.39495007	normal	0.396281904	-0.199286009	normal	--	--	--	--	--	[S]	Function unknown	--	Round spermatid basic protein 1-like protein GN=RSBN1L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: round spermatid basic protein 1-like protein [Galeopterus variegatus]
ENSG00000187260(WDR86)	--	0.698226726	21	0.27788357	7	0.331009613	10	0.0340489	1	0.066383329	1	0.0338108	1	0.012622432	-3.171835539	normal	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Nucleoporin Nup120/160"	WD repeat-containing protein 86 GN=WDR86 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	"PREDICTED: LOW QUALITY PROTEIN: WD repeat domain 86, partial [Trichechus manatus latirostris]"
ENSG00000187266(EPOR)	--	8.139069	314	6.37107	260	5.4248	222	3.65065	144	4.291122	165	3.89458	156	6.92E-06	-1.147020445	down	0.140665715	-0.672517394	normal	0.615669205	-0.513113354	normal	0.001332951	-0.79683323	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K05079|0|pon:100452294|EPOR; erythropoietin receptor; K05079 erythropoietin receptor (A)	Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640)	--	--	"Erythropoietin receptor, ligand binding;; Fibronectin type III domain"	Erythropoietin receptor (Precursor) GN=EPOR OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	erythropoietin receptor precursor [Sus scrofa] 
ENSG00000187268(FAM9C)	--	0	0	0	0	0.0381791	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cor1/Xlr/Xmr conserved region	Protein FAM9C GN=FAM9C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000187288(CIDEC)	--	0	0	0	0	0.119087	1	0.432547009	9	0.753426	15	0.242662495	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: intracellular (GO:0005622);; Biological Process: apoptotic process (GO:0006915);; 	--	--	--	--	CIDE-N domain	Cell death activator CIDE-3 GN=CIDEC OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: cell death activator CIDE-3 isoform X1 [Myotis davidii]
ENSG00000187325(TAF9B)	--	14.3786	538	13.8664	511	12.5137	456	15.0416	569	16.5477	620	13.662	516	0.971679362	0.049851778	normal	0.924431761	0.25682744	normal	0.955905788	0.169517003	normal	0.53154345	0.158373544	normal	[K]	Transcription	"Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	"K03133|0|pps:100988630|TAF9B; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; K03133 transcription initiation factor TFIID subunit 9B (A)"	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	"Transcription initiation factor IID, 31kD subunit"	Transcription initiation factor TFIID subunit 9B GN=TAF9B OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 9B [Bubalus bubalis]
ENSG00000187372(PCDHB13)	--	0.2632508	23	0.6469236	55	0.307942475	25	0.172212262	17	0.1853913	16	0.1904509	18	0.983186853	-0.433150383	normal	0.004430068	-1.710411894	down	0.980513214	-0.450011883	normal	0.247907224	-1.036049008	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56123|PCDHB13, PCDH-BETA13; protocadherin beta 13; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-13 (Precursor) GN=PCDHB13 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin beta-8 [Equus przewalskii]
ENSG00000187391(MAGI2)	--	0.668413644	74	0.454472439	48	0.631803675	68	0.309518563	35	0.274841354	30	0.371254452	40	0.129382007	-1.077706444	normal	0.896685303	-0.672457344	normal	0.722607033	-0.7517798	normal	0.073117127	-0.876180852	normal	[F]	Nucleotide transport and metabolism	Molecular Function: protein binding (GO:0005515);; 	"K05629|0|hsa:9863|MAGI2, ACVRIP1, AIP-1, AIP1, ARIP1, MAGI-2, SSCAM; membrane associated guanylate kinase, WW and PDZ domain containing 2; K05629 atrophin-1 interacting protein 1 (A)"	Rap1 signaling pathway (ko04015);; Tight junction (ko04530);; TNF signaling pathway (ko04668)	[R]	General function prediction only	PDZ domain (Also known as DHR or GLGF);; PDZ domain;; WW domain;; Guanylate kinase	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 GN=MAGI2 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 [Ovis aries]"
ENSG00000187446(CHP1)	--	95.421875	4958	104.2592581	5395	89.14206869	4611	71.71194815	3720	79.931811	4107	119.70243	6115	0.689238128	-0.445128038	normal	0.813671783	-0.414830839	normal	0.851787475	0.398867432	normal	0.794298891	-0.121977073	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	K17610|5.12095e-139|ptr:467662|CHP1; calcineurin-like EF-hand protein 1; K17610 calcineurin B homologous protein 1 (A)	--	[T]	Signal transduction mechanisms	EF-hand domain;; EF hand;; EF-hand domain pair;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region	Calcineurin B homologous protein 1 GN=CHP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	calcineurin B homologous protein 1 [Bos taurus] 
ENSG00000187479(C11orf96)	--	0.120525731	3	0	0	0	0	0.121151682	3	0.059029744	0	0.156937504	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C11orf96 GN=C11orf96 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C11orf96 homolog [Chrysochloris asiatica]
ENSG00000187486(KCNJ11)	--	2.2128894	73	0.942300797	47	1.061869902	42	0.98725306	26	0.4022488	17	0.485804728	22	0.004045165	-1.466257098	down	0.108548909	-1.410084563	normal	0.812761453	-0.895888653	normal	0.007233673	-1.339887229	down	--	--	Molecular Function: inward rectifier potassium channel activity (GO:0005242);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05004|0|hsa:3767|KCNJ11, BIR, HHF2, IKATP, KIR6.2, PHHI, TNDM3; potassium inwardly-rectifying channel, subfamily J, member 11; K05004 potassium inwardly-rectifying channel subfamily J member 11 (A)"	Insulin secretion (ko04911);; Type II diabetes mellitus (ko04930)	[P]	Inorganic ion transport and metabolism	Inward rectifier potassium channel	ATP-sensitive inward rectifier potassium channel 11 GN=KCNJ11 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: ATP-sensitive inward rectifier potassium channel 11 [Ursus maritimus]
ENSG00000187492(CDHR4)	--	0.04487276	2	0	0	0.17734597	3	0.12873732	3	0.3489077	6	0.044405772	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16504|0|hsa:389118|CDHR4, CDH29, PRO34300; cadherin-related family member 4; K16504 cadherin-related family member 4 (A)"	--	[T]	Signal transduction mechanisms	Cadherin domain	Cadherin-related family member 4 (Precursor) GN=CDHR4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: cadherin-related family member 4 [Galeopterus variegatus]
ENSG00000187498(COL4A1)	--	10.39916	1585	9.371571	1457	11.6752	1833	32.7394646	5038	37.845618	5751	22.795207	3482	0	1.636597717	up	0	1.958281984	up	5.08E-06	0.916859859	normal	1.54E-05	1.527944216	up	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Cellular Component: collagen trimer (GO:0005581);; 	"K06237|7.65942e-152|mcc:700281|COL4A1; collagen, type IV, alpha 1; K06237 collagen, type IV, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; C-terminal tandem repeated domain in type 4 procollagen	Arresten (Precursor) GN=COL4A1 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	"RecName: Full=Collagen alpha-1(IV) chain, partial [Bos taurus] "
ENSG00000187510(PLEKHG7)	--	0	0	0	0	0	0	0.1156476	2	0.0751661	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Pleckstrin homology domain-containing family G member 7 GN=PLEKHG7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family G member 7 [Pteropus alecto]
ENSG00000187513(GJA4)	--	0	0	0	0	0	0	0	0	0	0	0.036751016	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07613|0|pps:100988667|GJA4; gap junction protein, alpha 4, 37kDa; K07613 gap junction protein, alpha 4 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction alpha-4 protein GN=GJA4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: gap junction alpha-4 protein [Trichechus manatus latirostris]
ENSG00000187514(PTMA)	--	893.7133421	21119	942.8670003	22501	931.3036207	22275	760.6102146	18199	721.1206189	16897	604.8317209	14373	0.992364701	-0.245495346	normal	0.899733635	-0.434614719	normal	0.066803615	-0.640301092	normal	0.01524714	-0.435494832	normal	--	--	--	--	--	--	--	Prothymosin/parathymosin family	--	--	--	--
ENSG00000187522(HSPA14)	--	25.028737	1036	27.927353	1156	29.603874	1182	26.13013315	1083	29.84697242	1250	24.46182343	1124	0.979813469	0.033128923	normal	0.978198643	0.091245331	normal	0.978847345	-0.080773452	normal	0.968742065	0.014162497	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein	Heat shock 70 kDa protein 14 GN=HSPA14 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 14 isoform 1 [Canis lupus familiaris]
ENSG00000187527(ATP13A5)	--	0	0	0	0	0.254232004	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; 	K14951|0|hsa:344905|ATP13A5; ATPase type 13A5 (EC:3.6.3.-); K14951 cation-transporting ATPase 13A3/4/5 [EC:3.6.3.-] (A)	--	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; haloacid dehalogenase-like hydrolase;; P5-type ATPase cation transporter;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus"	Probable cation-transporting ATPase 13A5 GN=ATP13A5 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: probable cation-transporting ATPase 13A5 [Oryctolagus cuniculus]
ENSG00000187531(SIRT7)	--	41.659684	2889	51.39171	3632	48.84641763	3094	47.75609797	3071	45.18608	3103	55.800272	3681	0.9895108	0.057276499	normal	0.969178136	-0.248415023	normal	0.970833619	0.242224439	normal	0.969380825	0.014768756	normal	[K]	Transcription	Molecular Function: NAD+ binding (GO:0070403);; 	"K11417|0|hsa:51547|SIRT7, SIR2L7; sirtuin 7; K11417 NAD-dependent deacetylase sirtuin 7 [EC:3.5.1.-] (A)"	--	[BK]	Chromatin structure and dynamics;; Transcription	Sir2 family	NAD-dependent protein deacetylase sirtuin-7 GN=SIRT7 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	NAD-dependent protein deacetylase sirtuin-7 [Bos taurus] 
ENSG00000187535(IFT140)	--	8.456247	874	7.106441	817	7.791761005	849	6.109142	581	6.740009	676	8.26466	823	0.05256045	-0.618583445	normal	0.901962321	-0.294139813	normal	0.976413774	-0.053067552	normal	0.101327548	-0.308360557	normal	--	--	--	--	--	[R]	General function prediction only	"Region in Clathrin and VPS;; WD domain, G-beta repeat"	Intraflagellar transport protein 140 homolog GN=IFT140 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: intraflagellar transport protein 140 homolog isoform X1 [Equus przewalskii]
ENSG00000187546(AGMO)	--	1.034304509	30	0.435063518	14	0.6806511	16	3.866994399	105	3.67791	111	2.786407223	86	7.79E-06	1.726395274	up	8.78E-13	2.838361227	up	6.89E-08	2.31325623	up	1.02E-08	2.309460488	up	[I]	Lipid transport and metabolism	Molecular Function: iron ion binding (GO:0005506);; Biological Process: lipid biosynthetic process (GO:0008610);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K15537|0|hsa:392636|AGMO, TMEM195; alkylglycerol monooxygenase (EC:1.14.16.5); K15537 alkylglycerol monooxygenase [EC:1.14.16.5] (A)"	--	[I]	Lipid transport and metabolism	Fatty acid hydroxylase superfamily	Alkylglycerol monooxygenase GN=AGMO OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: alkylglycerol monooxygenase isoform X1 [Galeopterus variegatus]
ENSG00000187550(SBK2)	--	4.018282351	123	2.872382986	85	3.184978184	81	1.522467055	46	1.948882653	51	1.322247802	33	8.56E-05	-1.41960531	down	0.59635456	-0.741180768	normal	0.015379425	-1.26553266	normal	0.002829448	-1.174871672	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08858|1.1784e-178|hsa:646643|SBK2, SGK069; SH3 domain binding kinase family, member 2 (EC:2.7.11.1); K08858 serine/threonine-protein kinase SBK [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase SBK2 GN=SBK2 OS=Homo sapiens (Human) PE=3 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase SBK2 [Galeopterus variegatus]
ENSG00000187553(CYP26C1)	--	0	0	0	0	0	0	0.0974706	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K12665|0|hsa:340665|CYP26C1, FFDD4; cytochrome P450, family 26, subfamily C, polypeptide 1; K12665 cytochrome P450, family 26, subfamily C (A)"	Retinol metabolism (ko00830)	[QI]	"Secondary metabolites biosynthesis, transport and catabolism;; Lipid transport and metabolism"	Cytochrome P450	Cytochrome P450 26C1 GN=CYP26C1 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 26C1-like [Ceratotherium simum simum]
ENSG00000187554(TLR5)	--	0.177694861	11	0.19986056	13	0.035714201	1	0.071084635	4	0.229373597	11	0.087883663	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K10168|0|hsa:7100|TLR5, MELIOS, SLE1, SLEB1, TIL3; toll-like receptor 5; K10168 toll-like receptor 5 (A)"	Toll-like receptor signaling pathway (ko04620);; Pathogenic Escherichia coli infection (ko05130);; Salmonella infection (ko05132);; Legionellosis (ko05134);; Inflammatory bowel disease (IBD) (ko05321)	[T]	Signal transduction mechanisms	Leucine rich repeat;; TIR domain;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; TIR domain;; Leucine Rich repeat;; Leucine rich repeat	Toll-like receptor 5 (Precursor) GN=TLR5 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: toll-like receptor 5 isoform X2 [Galeopterus variegatus]
ENSG00000187555(USP7)	--	34.30691689	2985	38.31641991	3372	37.34270702	3235	37.5290701	3331	38.19315025	3315	30.51694361	2707	0.986944433	0.127330099	normal	0.990334566	-0.046001416	normal	0.959931994	-0.265226535	normal	0.821676026	-0.05814524	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11838|0|ptr:453907|USP7; ubiquitin specific peptidase 7 (herpes virus-associated); K11838 ubiquitin carboxyl-terminal hydrolase 7 [EC:3.4.19.12] (A)	FoxO signaling pathway (ko04068);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[O]	"Posttranslational modification, protein turnover, chaperones"	ICP0-binding domain of Ubiquitin-specific protease 7;; Ubiquitin-specific protease C-terminal;; Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; MATH domain	Ubiquitin carboxyl-terminal hydrolase 7 GN=USP7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 7 isoform 2 [Odobenus rosmarus divergens]
ENSG00000187556(NANOS3)	--	0.45887615	3	0.442658256	3	0.169897	1	0.516877	5	0.295698	1	0.41022	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18761|3.60631e-115|hsa:342977|NANOS3, NANOS1L, NOS3; nanos homolog 3 (Drosophila); K18761 protein nanos 3 (A)"	--	[R]	General function prediction only	Nanos RNA binding domain	Nanos homolog 3 GN=NANOS3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nanos homolog 3 [Vicugna pacos]
ENSG00000187559(FOXD4L3)	--	0.0311079	1	0.0307454	1	0.0889934	2	0.0619839	2	0	0	0.0606388	2	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09397|0|hsa:286380|FOXD4L3, FOXD4L2, FOXD6; forkhead box D4-like 3; K09397 forkhead box protein D (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein D4-like 6 GN=FOXD4L6 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: forkhead box protein D4 [Equus caballus]
ENSG00000187566(NHLRC1)	--	1.95894	72	2.238018	87	2.116272793	78	2.253856	84	1.905001	73	1.717914569	63	0.967002306	0.187846466	normal	0.955066521	-0.269425477	normal	0.954896966	-0.309719258	normal	0.850481394	-0.129520587	normal	--	--	--	K10602|0|ptr:747581|NHLRC1; NHL repeat containing E3 ubiquitin protein ligase 1; K10602 E3 ubiquitin-protein ligase NHLRC1 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	NHL repeat;; zinc-RING finger domain;; Ring finger domain	E3 ubiquitin-protein ligase NHLRC1 GN=NHLRC1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase NHLRC1 [Galeopterus variegatus]
ENSG00000187583(PLEKHN1)	--	1.400451493	66	1.227603709	55	1.3004333	59	2.247165831	109	1.905944433	86	1.167897001	52	0.576859368	0.680516436	normal	0.794212663	0.609966263	normal	0.973192297	-0.185428594	normal	0.422944142	0.433239684	normal	--	--	--	--	--	--	--	--	Pleckstrin homology domain-containing family N member 1 GN=PLEKHN1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family N member 1 isoform X1 [Panthera tigris altaica]
ENSG00000187595(ZNF385C)	--	0.2439362	13	0.446812	23	0.178949	8	0.2124585	10	0.264257	13	0.301034	16	--	--	--	0.962157383	-0.775879582	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies);; U1 zinc finger	Zinc finger protein 385C GN=ZNF385C OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 385C [Lipotes vexillifer]
ENSG00000187601(MAGEH1)	--	7.99939	196	5.86435	145	6.98707	173	7.90468	196	10.5681	260	7.05893	174	0.966691125	-0.030592453	normal	0.018706229	0.814603037	normal	0.967270651	2.36E-05	normal	0.459582476	0.272345132	normal	--	--	--	--	--	[S]	Function unknown	MAGE family	Melanoma-associated antigen H1 GN=MAGEH1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: melanoma-associated antigen H1-like [Camelus ferus] 
ENSG00000187605(TET3)	--	4.6915475	989	4.427576054	978	4.537665175	938	3.586092945	726	3.652947521	805	3.921599291	819	0.436088369	-0.475966315	normal	0.899040291	-0.301757006	normal	0.954979134	-0.203664219	normal	0.06199998	-0.326760318	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	Oxygenase domain of the 2OGFeDO superfamily;; CXXC zinc finger domain	Methylcytosine dioxygenase TET3 GN=TET3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: methylcytosine dioxygenase TET3 [Felis catus]
ENSG00000187607(ZNF286A)	--	10.60482528	610	12.41284617	721	15.54456073	638	8.606278629	616	12.75053827	732	10.34324047	619	0.973774722	-0.016669375	normal	0.97527579	0.000416963	normal	0.973116005	-0.051783835	normal	0.951909417	-0.022660307	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:57335|ZNF286A, ZNF286; zinc finger protein 286A; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain"	Zinc finger protein 286A GN=ZNF286A OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 286A [Equus caballus]
ENSG00000187608(ISG15)	--	5.524731469	47	4.396410568	39	5.709970868	51	11.2856009	100	10.57760108	90	7.571311051	66	0.055287922	1.034745835	normal	0.027542383	1.154756305	normal	0.955315961	0.354415869	normal	0.04068552	0.879956578	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K12159|3.25507e-107|pps:100989384|ISG15; ISG15 ubiquitin-like modifier; K12159 ubiquitin cross-reactive protein (A)	RIG-I-like receptor signaling pathway (ko04622)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin-like domain	Ubiquitin-like protein ISG15 (Precursor) GN=ISG15 OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like protein ISG15 [Tupaia chinensis] 
ENSG00000187609(EXD3)	--	6.160659	169	6.843101	188	6.4043019	184	4.136863	105	5.466472	136	5.35655	145	0.224676423	-0.709203925	normal	0.729158915	-0.483954101	normal	0.893790199	-0.348707937	normal	0.116144901	-0.507187734	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: 3'-5' exonuclease activity (GO:0008408);; 	--	--	[L]	"Replication, recombination and repair"	Mut7-C RNAse domain;; 3'-5' exonuclease	Exonuclease mut-7 homolog GN=EXD3 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: probable exonuclease mut-7 homolog isoform X6 [Equus caballus]
ENSG00000187624(C17orf97)	--	2.951809332	101	3.931454	124	2.189786248	77	4.4461015	153	3.502712017	123	4.244142518	149	0.653290777	0.561362179	normal	0.967459119	-0.032707846	normal	0.027745602	0.930720964	normal	0.206904174	0.47086617	normal	--	--	--	--	--	--	--	"Pectate lyase, N terminus"	Uncharacterized protein C17orf97 GN=C17orf97 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C17orf97 [Canis lupus familiaris]
ENSG00000187626(ZKSCAN4)	--	1.36157	90	1.377267713	83	1.033215	69	1.22673492	76	1.904721	116	1.564909268	99	0.955993645	-0.269739612	normal	0.867986579	0.454481606	normal	0.860135025	0.503285133	normal	0.645570781	0.24532803	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:387032|ZKSCAN4, P1P373C6, ZNF307, ZNF427, ZSCAN36, p373c6.1; zinc finger with KRAB and SCAN domains 4; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; XPA protein N-terminal"	Zinc finger protein with KRAB and SCAN domains 4 GN=ZKSCAN4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein with KRAB and SCAN domains 4 [Equus przewalskii]
ENSG00000187627(RGPD1)	--	0	0	0.007416967	1	0	0	0.014777266	2	0.00718287	0	0.009173546	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:729857|RGPD2, NUP358, RANBP2L2, RGP2; RANBP2-like and GRIP domain containing 2; K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; GRIP domain;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RANBP2-like and GRIP domain-containing protein 2 GN=RGPD2 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ceratotherium simum simum]
ENSG00000187630(DHRS4L2)	--	16.86762491	330	15.26626243	323	20.42596653	428	12.61483622	254	11.06348054	207	10.69419632	218	0.766455849	-0.406306493	normal	0.110732042	-0.659439631	normal	8.04E-05	-0.976645987	normal	0.001418143	-0.69210922	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K11147|1.35484e-137|nle:100604631|dehydrogenase/reductase SDR family member 4-like; K11147 dehydrogenase/reductase SDR family member 4 [EC:1.1.-.-] (A)	Retinol metabolism (ko00830);; Peroxisome (ko04146)	[R]	General function prediction only	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Dehydrogenase/reductase SDR family member 4-like 2 (Precursor) GN=DHRS4L2 OS=Homo sapiens (Human) PE=2 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 4 isoform X1 [Eptesicus fuscus]
ENSG00000187634(SAMD11)	--	3.756912182	158	2.851686774	132	3.50267158	150	3.990290942	164	4.659243392	218	3.484016538	163	0.967414474	0.02272212	normal	0.159133159	0.696097762	normal	0.963523819	0.11054859	normal	0.436722155	0.287798841	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Sterile alpha motif domain-containing protein 11 GN=SAMD11 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: sterile alpha motif domain-containing protein 11 isoform X6 [Canis lupus familiaris] 
ENSG00000187642(PERM1)	--	0.695537	16	0.573004454	18	0.8092504	20	0.720039	17	0.295952	6	0.388488526	11	--	--	--	--	--	--	0.97131957	-0.789314314	normal	--	--	--	--	--	--	--	--	--	--	--	PGC-1 and ERR-induced regulator in muscle protein 1 GN=PERM1 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: PGC-1 and ERR-induced regulator in muscle protein 1-like [Galeopterus variegatus]
ENSG00000187664(HAPLN4)	--	0.0161628	1	0.160046	10	0.0467478	2	0.0485516	3	0.0783366	4	0.0158964	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hyaluronic acid binding (GO:0005540);; Biological Process: cell adhesion (GO:0007155);; 	K06853|0|nle:100586330|HAPLN4; hyaluronan and proteoglycan link protein 4; K06853 hyaluronan and proteoglycan link protein 4 (A)	--	--	--	Extracellular link domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	Hyaluronan and proteoglycan link protein 4 (Precursor) GN=HAPLN4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: hyaluronan and proteoglycan link protein 4 [Equus przewalskii]
ENSG00000187672(ERC2)	--	0.0498959	3	0	0	0	0	0.030438762	3	0.078851517	7	0.03020349	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: presynaptic active zone (GO:0048786);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RIM-binding protein of the cytomatrix active zone	ERC protein 2 GN=ERC2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ERC protein 2 [Ursus maritimus] 
ENSG00000187676(B3GLCT)	--	3.841803204	249	4.490008278	291	4.5537506	289	6.227087559	405	4.845163535	313	5.672159102	366	0.061962818	0.667684671	normal	0.96379802	0.083299494	normal	0.868969312	0.330940498	normal	0.137312684	0.365397613	normal	--	--	"Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K13675|0|hsa:145173|B3GALTL, B3GLCT, B3GTL, B3Glc-T, Gal-T, beta3Glc-T; beta 1,3-galactosyltransferase-like; K13675 UDP-glucose:O-linked fucose beta-1,3-glucosyltransferase [EC:2.4.1.-] (A)"	Other types of O-glycan biosynthesis (ko00514)	--	--	Fringe-like;; Galactosyltransferase	"Beta-1,3-glucosyltransferase GN=B3GALTL OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-glucosyltransferase [Canis lupus familiaris]"
ENSG00000187678(SPRY4)	--	3.942285055	307	4.23565	342	3.075481681	253	2.398157	200	3.363757939	261	2.286318355	202	0.137389657	-0.645038047	normal	0.759862544	-0.409294427	normal	0.886288111	-0.330855407	normal	0.063329947	-0.465590308	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	K17385|0|nle:100601859|SPRY4; sprouty homolog 4 (Drosophila); K17385 protein sprouty homolog 4 (A)	Jak-STAT signaling pathway (ko04630)	--	--	Sprouty protein (Spry)	Protein sprouty homolog 4 GN=SPRY4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein sprouty homolog 4 isoform X2 [Bos taurus]
ENSG00000187682(ERAS)	--	0.267037509	3	0.261214966	3	0.084196226	0	0	0	0.08674846	0	0.087054084	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17196|8.73554e-143|pps:100979982|ERAS; ES cell expressed Ras; K17196 GTPase Eras (A)	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	GTPase ERas (Precursor) GN=ERAS OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: GTPase ERas [Orcinus orca] 
ENSG00000187688(TRPV2)	--	0.655829147	11	0.0245843	1	0.07251829	2	0.149540565	6	0.268227901	10	0.60443053	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04971|0|hsa:51393|TRPV2, VRL, VRL-1, VRL1; transient receptor potential cation channel, subfamily V, member 2; K04971 transient receptor potential cation channel subfamily V member 2 (A)"	Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ion transport protein	Transient receptor potential cation channel subfamily V member 2 GN=TRPV2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: transient receptor potential cation channel subfamily V member 2 [Galeopterus variegatus]
ENSG00000187689(AMTN)	--	0	0	0.116758458	2	0.114103612	1	0.398444967	7	0.865105	13	0.506254297	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: odontogenesis of dentin-containing tooth (GO:0042475);; Biological Process: positive regulation of enamel mineralization (GO:0070175);; 	--	--	--	--	--	Amelotin (Precursor) GN=AMTN OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: amelotin [Camelus bactrianus]
ENSG00000187690(CXorf67)	--	0	0	0	0	0	0	0	0	0	0	0.0345799	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein CXorf67 GN=CXorf67 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein CXorf67-like [Galeopterus variegatus]
ENSG00000187699(C2orf88)	--	0.858726	60	0.8626845	59	0.958198492	63	0.742331569	33	0.611532024	44	0.607986542	35	0.640049957	-0.863082529	normal	0.945291211	-0.431774868	normal	0.6595842	-0.829214454	normal	0.162316367	-0.721220606	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF4565)	Small membrane A-kinase anchor protein GN=C2orf88 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: small membrane A-kinase anchor protein isoform X1 [Tupaia chinensis]
ENSG00000187713(TMEM203)	--	34.1787	774	29.1166	679	34.5622	808	36.3582	841	36.3281	823	35.787	821	0.973691292	0.088770898	normal	0.929602821	0.255536681	normal	0.977153658	0.014708177	normal	0.63559261	0.115241705	normal	--	--	--	--	--	--	--	Transmembrane Fragile-X-F protein	Transmembrane protein 203 GN=TMEM203 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 203 [Orycteropus afer afer]
ENSG00000187720(THSD4)	--	49.81364027	7524	40.45571177	6580	37.19846804	6160	15.25890205	2639	17.21067479	2673	20.21479122	3457	0	-1.541783506	down	2.29E-13	-1.320561328	down	6.91E-05	-0.84142152	normal	2.09E-14	-1.22903528	down	--	--	Molecular Function: peptidase activity (GO:0008233);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ADAM-TS Spacer 1;; Thrombospondin type 1 domain;; PLAC (protease and lacunin) domain	Thrombospondin type-1 domain-containing protein 4 (Precursor) GN=THSD4 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thrombospondin type-1 domain-containing protein 4 [Ceratotherium simum simum]
ENSG00000187726(DNAJB13)	--	0.06717773	2	0	0	0.068796445	0	0.259400099	3	0.031215	0	0.087942605	2	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09519|0|hsa:374407|DNAJB13, RSPH16A, TSARG5, TSARG6; DnaJ (Hsp40) homolog, subfamily B, member 13; K09519 DnaJ homolog subfamily B member 13 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain;; DnaJ C terminal domain	DnaJ homolog subfamily B member 13 GN=DNAJB13 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dnaJ homolog subfamily B member 13 [Odobenus rosmarus divergens]
ENSG00000187730(GABRD)	--	0.592455278	9	0.238980153	7	0.137989437	3	0.035512799	1	0.035356547	0	0.106783014	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05184|0|hsa:2563|GABRD, EIG10, EJM7, GEFSP5; gamma-aminobutyric acid (GABA) A receptor, delta; K05184 gamma-aminobutyric acid receptor subunit delta (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Gamma-aminobutyric acid receptor subunit delta (Precursor) GN=GABRD OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit delta [Tupaia chinensis]
ENSG00000187735(TCEA1)	--	77.21643999	3468	82.4925498	3731	76.92358743	3433	86.10631014	3936	75.0611413	3375	86.06146721	3863	0.986678304	0.151730932	normal	0.984745509	-0.166030621	normal	0.98561149	0.161893113	normal	0.846551635	0.050318521	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: zinc ion binding (GO:0008270);; "	"K03145|0|nle:100589666|TCEA1; transcription elongation factor A (SII), 1; K03145 transcription elongation factor S-II (A)"	--	[K]	Transcription	"Transcription factor S-II (TFIIS), central domain;; Transcription factor S-II (TFIIS);; TFIIS helical bundle-like domain"	Transcription elongation factor A protein 1 GN=TCEA1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription elongation factor A protein 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000187736(NHEJ1)	--	8.407000692	257	10.26484389	287	8.448626304	256	5.295844836	159	7.53170807	182	4.449371194	154	0.073519291	-0.718059806	normal	0.113463361	-0.674038211	normal	0.059188317	-0.735839474	normal	0.004282298	-0.713902701	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: double-strand break repair (GO:0006302);; 	"K10980|0|hsa:79840|NHEJ1, XLF; nonhomologous end-joining factor 1; K10980 non-homologous end-joining factor 1 (A)"	Non-homologous end-joining (ko03450)	--	--	XLF (XRCC4-like factor)	Non-homologous end-joining factor 1 GN=NHEJ1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: non-homologous end-joining factor 1 isoform X2 [Physeter catodon]
ENSG00000187741(FANCA)	--	12.495415	999	13.07050998	1065	13.31422376	1080	12.02171176	906	11.6861556	922	11.02891548	850	0.964602701	-0.17152872	normal	0.948180778	-0.229091349	normal	0.829236316	-0.353229085	normal	0.16872218	-0.252728237	normal	--	--	--	"K10888|0|hsa:2175|FANCA, FA, FA-H, FA1, FAA, FACA, FAH, FANCH; Fanconi anemia, complementation group A; K10888 fanconi anemia group A protein (A)"	Fanconi anemia pathway (ko03460)	--	--	Fanconi anaemia group A protein	Fanconi anemia group A protein GN=FANCA OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: Fanconi anemia group A protein [Galeopterus variegatus]
ENSG00000187742(SECISBP2)	--	10.732958	684	9.516627018	634	9.395131854	672	9.133386	642	11.1262472	804	11.8134772	813	0.967726199	-0.121972414	normal	0.874154183	0.320605624	normal	0.922764416	0.26595776	normal	0.482291886	0.162526421	normal	--	--	--	--	--	--	--	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family	Selenocysteine insertion sequence-binding protein 2 GN=SECISBP2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: selenocysteine insertion sequence-binding protein 2 [Galeopterus variegatus]
ENSG00000187747(OR52B6)	--	0	0	0.10068	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:340980|OR52B6, OR11-47; olfactory receptor, family 52, subfamily B, member 6; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 52B6 GN=OR52B6 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 52B6-like [Myotis lucifugus]
ENSG00000187753(C9orf153)	--	0	0	0	0	0	0	0.030490194	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf153 GN=C9orf153 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf153 homolog [Equus przewalskii] 
ENSG00000187764(SEMA4D)	--	9.843619561	573	8.2740666	576	7.919793953	570	8.990059807	608	10.29593338	587	6.732813277	512	0.972166504	0.054561888	normal	0.972675947	0.00584992	normal	0.958549884	-0.162653981	normal	0.929170925	-0.031798195	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06521|0|pps:100994073|SEMA4D; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D; K06521 semaphorin 4 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat;; Immunoglobulin domain	Semaphorin-4D (Precursor) GN=SEMA4D OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: semaphorin-4D [Galeopterus variegatus]
ENSG00000187772(LIN28B)	--	2.490703742	217	2.660621535	219	2.314315839	196	2.22559528	185	2.316162133	191	2.130321823	188	0.93132523	-0.259013234	normal	0.942896747	-0.217177444	normal	0.965361682	-0.067877633	normal	0.624077398	-0.185542165	normal	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	K18754|4.14537e-164|pon:100438731|LIN28B; lin-28 homolog B (C. elegans); K18754 protein lin-28 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	'Cold-shock' DNA-binding domain;; Zinc knuckle	Protein lin-28 homolog B GN=LIN28B OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: protein lin-28 homolog B [Galeopterus variegatus]
ENSG00000187775(DNAH17)	--	0.156791021	53	0.1354074	46	0.0895179	30	0.0919137	31	0.15510501	52	0.0527895	18	0.812468437	-0.774833509	normal	0.975526124	0.150786725	normal	0.953863974	-0.699302732	normal	0.659878281	-0.37575106	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:8632|DNAH17, DNAHL1, DNEL2; dynein, axonemal, heavy chain 17; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Microtubule-binding stalk of dynein motor;; P-loop containing dynein motor region D3;; P-loop containing dynein motor region D4;; Hydrolytic ATP binding site of dynein motor region D1;; ATP-binding dynein motor region D5;; Dynein heavy chain, N-terminal region 1;; Dynein heavy chain, N-terminal region 2;; AAA domain (dynein-related subfamily);; AAA ATPase domain"	"Dynein heavy chain 17, axonemal GN=DNAH17 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 17, axonemal [Bubalus bubalis]"
ENSG00000187778(MCRS1)	--	25.34175091	898	26.42818576	896	25.43953937	904	29.44927029	1057	30.80214729	1081	29.05605074	1069	0.956624102	0.204033738	normal	0.93905802	0.248986265	normal	0.946288211	0.23321657	normal	0.225872365	0.228206512	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K11674|0|ptr:451881|MCRS1; microspherule protein 1; K11674 microspherule protein 1 (A)	Herpes simplex infection (ko05168)	[KT]	Transcription;; Signal transduction mechanisms	N-terminal region of micro-spherule protein;; FHA domain	Microspherule protein 1 GN=MCRS1 OS=Homo sapiens (Human) PE=1 SV=1	KT	Transcription;; Signal transduction mechanisms	PREDICTED: microspherule protein 1 isoform X1 [Galeopterus variegatus]
ENSG00000187790(FANCM)	--	2.611701623	281	3.210234995	377	3.892258442	431	2.801933379	293	3.533557287	363	3.078319851	304	0.967238791	0.029341162	normal	0.965646149	-0.075711995	normal	0.423693327	-0.509767138	normal	0.570896959	-0.202429447	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: nuclease activity (GO:0004518);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K10896|0|hsa:57697|FANCM, FAAP250, KIAA1596; Fanconi anemia, complementation group M (EC:3.6.4.13); K10896 fanconi anemia group M protein (A)"	Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; ERCC4 domain"	Fanconi anemia group M protein GN=FANCM OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: Fanconi anemia group M protein isoform X1 [Galeopterus variegatus]
ENSG00000187792(ZNF70)	--	1.165313652	155	1.043861148	137	1.145983904	150	1.098978978	146	1.119223666	149	1.230124663	166	0.963462042	-0.115947601	normal	0.963712015	0.098665354	normal	0.96107114	0.136619489	normal	0.95263579	0.039985005	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Rad4 beta-hairpin domain 1"	Zinc finger protein 70 GN=ZNF70 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 70 [Galeopterus variegatus]
ENSG00000187796(CARD9)	--	0.2405682	10	0.244413219	11	0.13007599	5	0.387576317	17	0.312981223	13	0.250310941	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K12794|0|hsa:64170|CARD9, CANDF2, hCARD9; caspase recruitment domain family, member 9; K12794 caspase recruitment domain-containing protein 9 (A)"	NOD-like receptor signaling pathway (ko04621);; Tuberculosis (ko05152)	--	--	Caspase recruitment domain	Caspase recruitment domain-containing protein 9 GN=CARD9 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: caspase recruitment domain-containing protein 9 isoform X1 [Equus caballus] 
ENSG00000187800(PEAR1)	--	0.844277076	80	0.601638904	61	1.037176948	101	4.225304105	410	3.856387082	379	3.491281937	344	0	2.305018553	up	0	2.584606502	up	2.71E-13	1.744728024	up	1.01E-22	2.206079171	up	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin EGF-like (Domains III and V);; Human growth factor-like EGF	Platelet endothelial aggregation receptor 1 (Precursor) GN=PEAR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: platelet endothelial aggregation receptor 1 [Equus caballus]
ENSG00000187801(ZFP69B)	--	1.499513684	102	1.118784995	87	1.417101711	124	0.491475769	44	0.632951314	57	0.700195556	64	0.005706317	-1.215127924	down	0.77496006	-0.618104751	normal	0.049852601	-0.946136962	normal	0.014331182	-0.943207119	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:65243|ZFP69B, ZKSCAN23B, ZNF643, ZSCAN54B; ZFP69 zinc finger protein B; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; SCAN domain"	Zinc finger protein ZFP69B GN=ZFP69B OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein ZFP69B [Felis catus]
ENSG00000187808(SOWAHD)	--	0.567252	14	0.266844	7	1.00592	26	0.236445	6	0.273061	6	0.238163	6	--	--	--	--	--	--	0.238954656	-1.87998098	normal	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein SOWAHD GN=SOWAHD OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein SOWAHD [Ceratotherium simum simum]
ENSG00000187815(ZFP69)	--	0.117338132	5	0.163673318	7	0	0	0.1397035	8	0.082199558	4	0.139231494	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:339559|ZFP69, ZFP69A, ZKSCAN23A, ZNF642, ZSCAN54A; ZFP69 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein ZFP69 GN=ZFP69 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein ZFP69 isoform X3 [Galeopterus variegatus]
ENSG00000187824(TMEM220)	--	2.613288569	72	2.3746445	64	1.58076112	57	0.821667	38	1.010169022	43	1.3722014	48	0.376423915	-0.925186865	normal	0.887751594	-0.578377161	normal	0.970454473	-0.249010681	normal	0.246622898	-0.601983807	normal	--	--	--	--	--	--	--	"Transmembrane family 220, helix"	Transmembrane protein 220 GN=TMEM220 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 220 [Orcinus orca]
ENSG00000187837(HIST1H1C)	--	41.1419	308	51.9749	401	46.3636	363	28.1224	225	23.2785	175	28.5868	221	0.599799639	-0.481017245	normal	3.58E-07	-1.21055872	down	0.031010084	-0.720328505	normal	0.000165535	-0.809010819	normal	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K11275|1.64294e-39|ptr:471878|HIST1H1C; histone cluster 1, H1c; K11275 histone H1/5 (A)"	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	Histone H1.2 GN=HIST1H1C OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"histone H1.2-like protein, partial [Panthera tigris altaica]"
ENSG00000187838(PLSCR3)	--	35.859272	724	19.085963	506	30.17075892	629	30.33418503	620	28.8829004	640	16.485218	398	0.928130727	-0.253970594	normal	0.876200293	0.316664765	normal	0.029737301	-0.666550415	normal	0.677965913	-0.187262884	normal	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Scramblase	Phospholipid scramblase 3 GN=PLSCR3 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: phospholipid scramblase 3 [Galeopterus variegatus] 
ENSG00000187840(EIF4EBP1)	--	84.26	1593	80.6057	1603	76.3794	1527	77.284	1487	71.3039	1337	95.1338	1834	0.978366215	-0.130044023	normal	0.929953953	-0.282908811	normal	0.94891093	0.255770698	normal	0.895946735	-0.040680448	normal	--	--	Molecular Function: eukaryotic initiation factor 4E binding (GO:0008190);; Biological Process: negative regulation of translational initiation (GO:0045947);; 	K07205|2.49072e-79|ptr:464114|EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1; K07205 eukaryotic translation initiation factor 4E binding protein 1 (A)	RNA transport (ko03013);; ErbB signaling pathway (ko04012);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Acute myeloid leukemia (ko05221);; Choline metabolism in cancer (ko05231)	--	--	Eukaryotic translation initiation factor 4E binding protein (EIF4EBP)	Eukaryotic translation initiation factor 4E-binding protein 1 GN=EIF4EBP1 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 4E-binding protein 1 [Equus caballus]
ENSG00000187848(P2RX2)	--	0.028380204	1	0.058072991	2	0	0	0	0	0	0	0.080535467	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: purinergic nucleotide receptor activity (GO:0001614);; Molecular Function: extracellular ATP-gated cation channel activity (GO:0004931);; Cellular Component: integral component of plasma membrane (GO:0005887);; Biological Process: response to ATP (GO:0033198);; Biological Process: cation transmembrane transport (GO:0098655);; 	"K05216|0|mcf:102121756|P2RX2; purinergic receptor P2X, ligand-gated ion channel, 2; K05216 P2X purinoceptor 2 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080)	--	--	ATP P2X receptor	P2X purinoceptor 2 GN=P2RX2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: P2X purinoceptor 2 isoform X1 [Bubalus bubalis]
ENSG00000187860(CCDC157)	--	1.955878	55	1.1223705	39	1.978174677	69	1.020746891	34	1.368523001	47	1.507043019	54	0.856339174	-0.699628174	normal	0.974094377	0.239297977	normal	0.953219312	-0.353157125	normal	0.663383517	-0.290919955	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 157 GN=CCDC157 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 157 [Ceratotherium simum simum]
ENSG00000187866(FAM122A)	--	4.45518	277	4.8102	298	4.59961	281	5.64809	354	6.40905	399	6.0122	376	0.879427413	0.321450699	normal	0.768056405	0.397899297	normal	0.746097913	0.409957342	normal	0.115622724	0.378345571	normal	--	--	--	--	--	--	--	--	Protein FAM122A GN=FAM122A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM122A [Oryctolagus cuniculus]
ENSG00000187867(PALM3)	--	2.249190695	157	1.615811398	118	1.85570181	89	0.316288295	23	0.570110747	39	0.12380904	9	3.33E-16	-2.721532507	down	1.35E-05	-1.581618574	down	4.42E-12	-3.113662787	down	6.54E-06	-2.381204256	down	--	--	--	--	--	--	--	--	Paralemmin-3 (Precursor) GN=PALM3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: paralemmin-3 [Camelus bactrianus]
ENSG00000187871(GFRAL)	--	0	0	0	0	0	0	0	0	0	0	0.0349572	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GDNF/GAS1 domain	GDNF family receptor alpha-like (Precursor) GN=GFRAL OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: GDNF family receptor alpha-like [Galeopterus variegatus]
ENSG00000187889(C1orf168)	--	0	0	0	0	0.108627	6	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Helically-extended SH3 domain	Uncharacterized protein C1orf168 GN=C1orf168 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf168 homolog [Galeopterus variegatus]
ENSG00000187902(SHISA7)	--	0.026644483	3	0.02667044	3	0.034726947	3	0.035907295	4	0.050387695	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Wnt and FGF inhibitory regulator	Protein shisa-7 (Precursor) GN=SHISA7 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein shisa-7 [Odobenus rosmarus divergens]
ENSG00000187905(LRRC74B)	--	0.0459383	1	0	0	0	0	0	0	0	0	0.0453087	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 74B {ECO:0000312|HGNC:HGNC:34301} OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein LOC400891-like [Myotis lucifugus]
ENSG00000187908(DMBT1)	--	0.008341771	1	0	0	0.00634703	0	0.230473205	35	0.230065037	35	0.091473683	14	5.81E-06	3.827622252	up	4.39E-07	4.583345439	up	--	--	--	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	K13912|0|ggo:101129226|DMBT1; LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 protein; K13912 deleted in malignant brain tumors 1 protein (A)	Salivary secretion (ko04970)	--	--	Scavenger receptor cysteine-rich domain;; CUB domain;; Scavenger receptor cysteine-rich domain;; Zona pellucida-like domain;; CUB-like domain	Deleted in malignant brain tumors 1 protein (Precursor) GN=DMBT1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: deleted in malignant brain tumors 1 [Odobenus rosmarus divergens]
ENSG00000187918(OR51I2)	--	0	0	0	0	0	0	0	0	0	0	0.21466	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:390064|OR51I2, OR11-38; olfactory receptor, family 51, subfamily I, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 51I2 GN=OR51I2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 51I2-like [Equus caballus]
ENSG00000187942(LDLRAD2)	--	0.012658	1	0	0	0.0795165	4	0	0	0.0605361	3	0.0409311	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Low-density lipoprotein receptor domain class A	Low-density lipoprotein receptor class A domain-containing protein 2 (Precursor) GN=LDLRAD2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor class A domain-containing protein 2 [Pteropus alecto]
ENSG00000187944(C2orf66)	--	0.100186	2	0.154102	3	0	0	0.0501992	1	0.194168	3	0.149138	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf66 (Precursor) GN=C2orf66 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C2orf66 homolog [Oryctolagus cuniculus]
ENSG00000187951(ARHGAP11B)	--	5.96849386	321	5.915799159	324	6.54318	321	4.691284836	226	4.93068345	254	6.222543507	327	0.421427377	-0.534019212	normal	0.827964497	-0.370632708	normal	0.968155426	0.018340288	normal	0.30291181	-0.279544187	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	RhoGAP domain	Rho GTPase-activating protein 11B GN=ARHGAP11B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 11A isoform X2 [Ursus maritimus]
ENSG00000187954(CYHR1)	--	41.37187619	1177	36.20159753	1140	41.19790816	1212	35.70311812	1058	32.68063582	956	39.63584355	1170	0.964452576	-0.184352966	normal	0.925226396	-0.274978927	normal	0.980372228	-0.059097555	normal	0.398481899	-0.169267338	normal	--	--	--	--	--	[R]	General function prediction only	--	Cysteine and histidine-rich protein 1 GN=CYHR1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: cysteine and histidine-rich protein 1-A isoform 1 [Dasypus novemcinctus]
ENSG00000187955(COL14A1)	--	0.018699451	1	0.074446243	4	0.036907222	1	0	0	0.007004321	0	0.134400783	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K08133|0|hsa:7373|COL14A1, UND; collagen, type XIV, alpha 1; K08133 collagen, type XIV, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	"von Willebrand factor type A domain;; Fibronectin type III domain;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; Interferon-alpha/beta receptor, fibronectin type III"	Collagen alpha-1(XIV) chain (Precursor) OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: collagen alpha-1(XIV) chain isoform X1 [Sus scrofa]
ENSG00000187957(DNER)	--	16.28397	919	15.334744	877	18.91042	1050	12.00701	639	9.47252	528	12.844465	730	0.163231625	-0.553963713	normal	0.003336831	-0.751775819	normal	0.222255961	-0.531788614	normal	0.000257018	-0.605787977	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EGF-like domain;; Human growth factor-like EGF;; EGF-like domain;; EGF domain;; Laminin EGF-like (Domains III and V)	Delta and Notch-like epidermal growth factor-related receptor (Precursor) GN=DNER OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: delta and Notch-like epidermal growth factor-related receptor [Mustela putorius furo]
ENSG00000187961(KLHL17)	--	5.174967843	260	3.446210048	174	4.267407483	213	4.041412519	194	3.522923186	175	3.459140743	179	0.71732232	-0.450194976	normal	0.965969121	-0.013045883	normal	0.932686763	-0.257190727	normal	0.448099809	-0.261006155	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10454|0|hsa:339451|KLHL17; kelch-like family member 17; K10454 kelch-like protein 17 (actinfilin) (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Kelch-like protein 17 GN=KLHL17 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 17 isoform X1 [Mustela putorius furo]
ENSG00000187969(ZCCHC13)	--	0	0	0	0	0	0	0	0	0	0	0.078549	1	--	--	--	--	--	--	--	--	--	--	--	--	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Zinc knuckle;; Zinc knuckle	Zinc finger CCHC domain-containing protein 13 GN=ZCCHC13 OS=Homo sapiens (Human) PE=2 SV=1	OU	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: cellular nucleic acid-binding protein-like [Equus caballus]
ENSG00000187994(RINL)	--	2.00920195	75	1.711102389	85	1.665807464	55	1.152685216	57	2.328469172	79	1.18976921	53	0.934840417	-0.416929745	normal	0.968548844	-0.124734134	normal	0.977455693	-0.060048616	normal	0.746526681	-0.207792818	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Vacuolar sorting protein 9 (VPS9) domain	Ras and Rab interactor-like protein GN=RINL OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras and Rab interactor-like protein [Tursiops truncatus]
ENSG00000188001(TPRG1)	--	1.224154501	53	1.182066228	51	1.102440085	49	1.084423363	40	0.883722382	38	0.622740855	27	0.955846244	-0.422670391	normal	0.954065057	-0.431061675	normal	0.796128391	-0.832998011	normal	0.338728844	-0.565495249	normal	--	--	--	--	--	--	--	Inositol phosphatase	Tumor protein p63-regulated gene 1 protein GN=TPRG1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: tumor protein p63-regulated gene 1 protein isoform X1 [Oryctolagus cuniculus]
ENSG00000188004(C1orf204)	--	0.753405735	21	0.569273	25	0.6224282	24	1.062445019	23	1.1823827	39	0.494333428	17	0.988037224	0.093850213	normal	0.947624447	0.591282858	normal	0.98074125	-0.470416111	normal	0.891771585	0.153016744	normal	--	--	--	--	--	--	--	--	V-set and immunoglobulin domain-containing protein 8 (Precursor) GN=VSIG8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: V-set and immunoglobulin domain-containing protein 8-like [Dasypus novemcinctus]
ENSG00000188010(MORN2)	--	17.24467485	169	23.85150209	237	21.42650134	211	15.84490124	161	15.43920619	148	19.71196825	195	0.96403535	-0.099864478	normal	0.129070529	-0.6950498	normal	0.961140846	-0.121156772	normal	0.35239125	-0.312501699	normal	[S]	Function unknown	--	--	--	--	--	MORN repeat	MORN repeat-containing protein 2 GN=MORN2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: MORN repeat-containing protein 2 [Condylura cristata]
ENSG00000188015(S100A3)	--	13.83148	127	12.71116	115	13.70289	127	43.1716	423	32.1181	307	38.4447	373	8.03E-14	1.693118471	up	4.08E-08	1.383610833	up	5.09E-11	1.534880823	up	5.86E-13	1.558124465	up	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A3 GN=S100A3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein S100-A3 [Oryctolagus cuniculus]
ENSG00000188021(UBQLN2)	--	17.3304	1205	20.7879	1428	18.8806	1294	21.0323	1455	20.6422	1434	22.3929	1563	0.949590355	0.240873928	normal	0.983082816	-0.01536128	normal	0.940126706	0.263907695	normal	0.421544869	0.159972113	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K04523|0|pon:100443736|UBQLN2; ubiquilin 2; K04523 ubiquilin (A)	Protein processing in endoplasmic reticulum (ko04141)	[OR]	"Posttranslational modification, protein turnover, chaperones;; General function prediction only"	Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like;; UBA/TS-N domain	Ubiquilin-2 GN=UBQLN2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquilin-2 [Galeopterus variegatus]
ENSG00000188026(RILPL1)	--	9.32115602	497	9.742981	551	9.129058	501	8.665983868	465	8.379668008	467	9.093792	481	0.963425997	-0.126443166	normal	0.921966009	-0.259282317	normal	0.969640761	-0.066859164	normal	0.559003512	-0.153764459	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	--	--	JNK_SAPK-associated protein-1;; Rab interacting lysosomal protein	RILP-like protein 1 GN=RILPL1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: RILP-like protein 1 isoform X1 [Sus scrofa]
ENSG00000188033(ZNF490)	--	0.450759497	43	0.4769871	48	0.38557312	39	0.7661671	60	0.360863365	37	0.678653825	70	0.947664693	0.436538899	normal	0.96283835	-0.383146451	normal	0.618699515	0.811782577	normal	0.598137803	0.340157807	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:468734|ZNF490; zinc finger protein 490; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 490 GN=ZNF490 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 709-like [Leptonychotes weddellii]
ENSG00000188037(CLCN1)	--	0.0171874	1	0	0	0.0666462	3	0.0171219	1	0.0838478	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: voltage-gated chloride channel activity (GO:0005247);; Biological Process: chloride transport (GO:0006821);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05010|0|hsa:1180|CLCN1, CLC1; chloride channel, voltage-sensitive 1; K05010 chloride channel 1, skeletal muscle (A)"	--	[P]	Inorganic ion transport and metabolism	Voltage gated chloride channel;; CBS domain	Chloride channel protein 1 GN=CLCN1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: chloride channel protein 1 [Camelus ferus]
ENSG00000188038(NRN1L)	--	0	0	0.296519706	2	0.143802694	0	0.291505567	2	0	0	0.298090513	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Neuritin protein family	Neuritin-like protein (Precursor) GN=NRN1L OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	Neuritin-like protein [Pteropus alecto]
ENSG00000188039(NWD1)	--	0.007305679	1	0	0	0	0	0	0	0	0	0.014533492	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; NACHT domain;; Nup133 N terminal like;; AAA ATPase domain"	NACHT and WD repeat domain-containing protein 1 GN=NWD1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: NACHT and WD repeat domain-containing protein 1 [Galeopterus variegatus]
ENSG00000188042(ARL4C)	--	158.7636	10740	126.67695	8681	123.01458	8364	99.91806	6802	134.85594	9130	78.15861	5300	0.010554665	-0.68967019	normal	0.995480601	0.051318343	normal	0.017646642	-0.666339445	normal	0.233425462	-0.409896043	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07945|2.82441e-136|hsa:10123|ARL4C, ARL7, LAK; ADP-ribosylation factor-like 4C; K07945 ADP-ribosylation factor-like protein 4 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family;; Ras family;; Signal recognition particle receptor beta subunit;; Miro-like protein;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	ADP-ribosylation factor-like protein 4C GN=ARL4C OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 4C [Sorex araneus]
ENSG00000188050(RNF133)	--	0	0	0.139335	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K15702|0|hsa:168433|RNF133; ring finger protein 133; K15702 E3 ubiquitin-protein ligase RNF133 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; PA domain;; zinc-RING finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF133 GN=RNF133 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF133-like [Dasypus novemcinctus]
ENSG00000188060(RAB42)	--	2.546491635	104	1.571198414	68	1.489915952	83	0.834931	38	0.306923025	12	0.496035704	29	0.000267545	-1.446494292	down	1.07E-06	-2.382990826	down	0.001378232	-1.477782534	down	3.84E-05	-1.7131829	down	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07929|6.02647e-137|hsa:115273|RAB42; RAB42, member RAS oncogene family; K07929 Ras-related protein Rab-42 (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region	Putative Ras-related protein Rab-42 GN=RAB42 OS=Homo sapiens (Human) PE=5 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: putative Ras-related protein Rab-42 [Oryctolagus cuniculus]
ENSG00000188064(WNT7B)	--	95.17729223	6889	93.46650118	6608	99.22749882	7423	47.1755634	3550	41.30802	2888	46.97979668	3318	3.10E-07	-0.986995165	normal	3.58E-11	-1.215136314	down	1.26E-10	-1.169613676	down	3.29E-16	-1.121825764	down	--	--	Molecular Function: receptor binding (GO:0005102);; Cellular Component: extracellular region (GO:0005576);; Biological Process: multicellular organismal development (GO:0007275);; Biological Process: Wnt signaling pathway (GO:0016055);; 	"K00572|0|pps:100977315|WNT7B; wingless-type MMTV integration site family, member 7B; K00572 wingless-type MMTV integration site family, member 7 (A)"	Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	wnt family	Protein Wnt-7b (Precursor) GN=WNT7B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein Wnt-7b [Equus przewalskii]
ENSG00000188070(C11orf95)	--	3.533724091	289	3.91518154	248	3.458105391	280	3.960275336	361	5.104831299	499	4.765585814	368	0.905034273	0.288721446	normal	4.87E-05	0.98296536	normal	0.797238621	0.384172239	normal	0.024676028	0.567040954	normal	--	--	--	--	--	--	--	BED zinc finger	Uncharacterized protein C11orf95 GN=C11orf95 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"PREDICTED: uncharacterized protein C11orf95 homolog, partial [Lipotes vexillifer]"
ENSG00000188089(PLA2G4E)	--	0.0177845	2	0.0088454	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipase activity (GO:0004620);; Biological Process: phospholipid catabolic process (GO:0009395);; 	"K16342|0|hsa:123745|PLA2G4E; phospholipase A2, group IVE (EC:3.1.1.4); K16342 cytosolic phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; VEGF signaling pathway (ko04370);; Platelet activation (ko04611);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Glutamatergic synapse (ko04724);; Serotonergic synapse (ko04726);; Long-term depression (ko04730);; Inflammatory mediator regulation of TRP channels (ko04750);; GnRH signaling pathway (ko04912);; Ovarian steroidogenesis (ko04913);; Oxytocin signaling pathway (ko04921);; Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Lysophospholipase catalytic domain;; C2 domain	Cytosolic phospholipase A2 epsilon GN=PLA2G4E OS=Homo sapiens (Human) PE=2 SV=3	I	Lipid transport and metabolism	PREDICTED: cytosolic phospholipase A2 epsilon [Loxodonta africana]
ENSG00000188092(GPR89B)	--	0.222251699	6	0.37198391	10	0.477228318	12	0.658792513	18	0.467712858	12	0.844525396	23	--	--	--	--	--	--	0.957220836	0.851661507	normal	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[T]	Signal transduction mechanisms	Abscisic acid G-protein coupled receptor;; Protein of unknown function (DUF3735)	Golgi pH regulator B GN=GPR89B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: Golgi pH regulator-like isoform X1 [Bos mutus] 
ENSG00000188095(MESP2)	--	0.363105	6	0.0377043	1	0.2682446	5	0.233163	6	0.11809142	2	0.304767305	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09076|0|hsa:145873|MESP2, SCDO2, bHLHc6; mesoderm posterior basic helix-loop-helix transcription factor 2; K09076 mesoderm posterior (A)"	--	--	--	Helix-loop-helix DNA-binding domain	Mesoderm posterior protein 2 GN=MESP2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: mesoderm posterior protein 2 [Tursiops truncatus]
ENSG00000188100(FAM25A)	--	0	0	0	0	0	0	0	0	0	0	0.621908	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM25G GN=FAM25G OS=Homo sapiens (Human) PE=3 SV=1	--	--	PREDICTED: protein FAM25C-like [Echinops telfairi]
ENSG00000188107(EYS)	--	0.1299713	24	0.064140258	5	0.0273405	4	0.0757444	14	0.0684872	12	0.1045472	15	0.965120419	-0.745280728	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Laminin G domain;; EGF-like domain;; Laminin G domain;; Concanavalin A-like lectin/glucanases superfamily	Protein eyes shut homolog (Precursor) GN=UNQ9424/PRO34591 OS=Homo sapiens (Human) PE=1 SV=5	T	Signal transduction mechanisms	PREDICTED: protein eyes shut homolog [Canis lupus familiaris]
ENSG00000188112(C6orf132)	--	0.256536983	36	0.390132075	36	0.482581	39	1.379232432	84	0.9797119	83	0.8475979	74	0.039679628	1.158322234	normal	0.0440604	1.150994907	normal	0.429711038	0.890298201	normal	0.011070341	1.097078394	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C6orf132 GN=C6orf132 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: uncharacterized protein LOC101401392 [Ceratotherium simum simum]
ENSG00000188124(OR2AG2)	--	0	0	0.0741036	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:338755|OR2AG2, OR11-76, OR2AG2P; olfactory receptor, family 2, subfamily AG, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 2AG2 GN=OR2AG2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 2AG2-like [Dasypus novemcinctus]
ENSG00000188133(TMEM215)	--	0.0164908	1	0	0	0	0	0.0814267	5	0.159887	9	0.0981135	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 215 GN=TMEM215 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 215 [Ochotona princeps]
ENSG00000188152(NUTM2G)	--	0.3036212	18	0.2640652	15	0.430726	25	0.5407668	32	0.506312	29	0.4723789	28	0.942406682	0.750647444	normal	0.925654077	0.86593606	normal	0.985203738	0.146812065	normal	0.415458863	0.596958659	normal	--	--	--	--	--	--	--	NUT protein N terminus;; NUT protein C terminal	NUT family member 2G GN=NUTM2G OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: NUT family member 2G-like [Equus caballus]
ENSG00000188153(COL4A5)	--	11.4531483	1548	7.99580001	1144	8.077968892	1192	22.97055133	2885	21.168772	2809	19.17585208	2278	3.12E-05	0.866693966	normal	6.78E-12	1.273433536	up	4.94E-06	0.925228327	normal	2.60E-08	1.015411073	up	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Cellular Component: collagen trimer (GO:0005581);; 	"K06237|5.65916e-174|ssc:100519180|COL4A5; collagen, type IV, alpha 5; K06237 collagen, type IV, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; C-terminal tandem repeated domain in type 4 procollagen	Collagen alpha-5(IV) chain (Precursor) GN=COL4A5 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	"PREDICTED: collagen alpha-5(IV) chain-like, partial [Tursiops truncatus]"
ENSG00000188157(AGRN)	--	91.593427	12713	82.12352574	11682	80.93662005	11663	90.21496397	12529	84.53212197	11696	85.20498632	11883	0.996754317	-0.051859195	normal	0.996546731	-0.019696083	normal	0.996693395	0.018666335	normal	0.956825328	-0.019432112	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: G-protein coupled acetylcholine receptor signaling pathway (GO:0007213);; Biological Process: receptor clustering (GO:0043113);; Molecular Function: laminin binding (GO:0043236);; 	"K06254|0|hsa:375790|AGRN, CMSPPD; agrin; K06254 agrin (A)"	ECM-receptor interaction (ko04512)	[O]	"Posttranslational modification, protein turnover, chaperones"	Laminin G domain;; Agrin NtA domain;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain;; Laminin G domain;; Laminin EGF-like (Domains III and V);; SEA domain;; EGF-like domain;; Concanavalin A-like lectin/glucanases superfamily	Agrin C-terminal 22 kDa fragment (Precursor) GN=AGRN OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: agrin [Bubalus bubalis]
ENSG00000188158(NHS)	--	3.412484341	581	3.32442461	555	4.304087054	721	5.463982731	921	4.772895874	809	4.138555346	704	0.039362736	0.632491634	normal	0.298367104	0.521043057	normal	0.974936522	-0.042624792	normal	0.079815391	0.3688024	normal	--	--	--	--	--	--	--	NHS-like	Nance-Horan syndrome protein GN=NHS OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: nance-Horan syndrome protein isoform 2 [Odobenus rosmarus divergens]
ENSG00000188163(FAM166A)	--	0.05226	1	0.102056103	2	0	0	0	0	0	0	0.0501428	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF2475)	Protein FAM166A GN=FAM166A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM166A [Ursus maritimus]
ENSG00000188175(HEPACAM2)	--	0.03107872	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	HEPACAM family member 2 (Precursor) GN=HEPACAM2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: HEPACAM family member 2 isoform X1 [Lipotes vexillifer]
ENSG00000188176(SMTNL2)	--	0	0	0.027699267	1	0.142430419	4	0	0	0.200479828	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Calponin homology (CH) domain;; CAMSAP CH domain	Smoothelin-like protein 2 GN=SMTNL2 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: smoothelin-like protein 2 [Ochotona princeps]
ENSG00000188177(ZC3H6)	--	0.605876798	114	0.451126282	84	0.55919442	101	0.284053191	53	0.352397654	66	0.486743472	92	0.009883508	-1.113247957	down	0.938861647	-0.361978754	normal	0.966613632	-0.140732232	normal	0.226878001	-0.522340603	normal	[R]	General function prediction only	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[A]	RNA processing and modification	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Zinc finger CCCH domain-containing protein 6 GN=ZC3H6 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: zinc finger CCCH domain-containing protein 6 [Balaenoptera acutorostrata scammoni]
ENSG00000188186(LAMTOR4)	--	111.9878329	789	135.6418487	974	129.163391	945	88.356659	642	83.6931399	579	103.480886	725	0.862327211	-0.327575603	normal	0.001835295	-0.770215479	normal	0.745090265	-0.389910225	normal	0.002415464	-0.497506961	normal	--	--	--	--	--	--	--	--	"Ragulator complex protein LAMTOR4, N-terminally processed GN=LAMTOR4 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	PREDICTED: ragulator complex protein LAMTOR4 isoform X2 [Oryctolagus cuniculus]
ENSG00000188191(PRKAR1B)	--	13.91154149	673	18.9442462	809	19.06517414	848	22.2041587	1082	25.24310197	940	20.33101697	950	0.022395075	0.653004063	normal	0.957201073	0.194756504	normal	0.966978779	0.155309999	normal	0.05881584	0.329684027	normal	--	--	--	"K04739|0|hsa:5575|PRKAR1B, PRKAR1; protein kinase, cAMP-dependent, regulatory, type I, beta (EC:2.7.11.1); K04739 cAMP-dependent protein kinase regulator (A)"	Apoptosis (ko04210);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	Cyclic nucleotide-binding domain;; Regulatory subunit of type II PKA R-subunit	cAMP-dependent protein kinase type I-beta regulatory subunit GN=PRKAR1B OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: cAMP-dependent protein kinase type I-beta regulatory subunit [Ceratotherium simum simum]
ENSG00000188199(NUTM2B)	--	0.2919433	22	0.3375459	26	0.3237564	25	0.1640609	13	0.1979143	12	0.230975565	17	0.971576593	-0.723417713	normal	0.892719098	-1.04544308	normal	0.97743092	-0.525894271	normal	0.25909667	-0.817886506	normal	--	--	--	--	--	--	--	NUT protein N terminus;; NUT protein C terminal	NUT family member 2B GN=NUTM2B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: NUT family member 2G-like [Equus caballus]
ENSG00000188211(NCR3LG1)	--	3.463558686	731	3.416573	718	2.961275977	614	3.229742202	678	3.678850974	770	6.657986033	1407	0.96606654	-0.139114679	normal	0.972870278	0.079286768	normal	7.71E-10	1.18603578	up	0.520570146	0.449475206	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: viral capsid (GO:0019028);; 	"K16349|0|hsa:374383|NCR3LG1, B7-H6, B7H6, DKFZp686O24166; natural killer cell cytotoxicity receptor 3 ligand 1; K16349 natural cytotoxicity triggering receptor 3 ligand 1 (A)"	--	--	--	"Immunoglobulin C1-set domain;; Matrix protein (MA), p15;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain"	Natural cytotoxicity triggering receptor 3 ligand 1 (Precursor) GN=NCR3LG1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: natural cytotoxicity triggering receptor 3 ligand 1 [Lipotes vexillifer]
ENSG00000188215(DCUN1D3)	--	11.37720401	641	10.235306	553	11.30461028	659	11.6997965	728	11.8641127	715	13.249924	753	0.963373749	0.152438821	normal	0.834674589	0.348397285	normal	0.957112258	0.183685354	normal	0.286831775	0.224127174	normal	--	--	--	"K17823|0|hsa:123879|DCUN1D3, 44M2.4; DCN1, defective in cullin neddylation 1, domain containing 3 (EC:3.1.-.-); K17823 DCN1-like protein 3 (A)"	--	[S]	Function unknown	Cullin binding	DCN1-like protein 3 GN=DCUN1D3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DCN1-like protein 3 [Camelus ferus] 
ENSG00000188219(POTEE)	--	0.109873	10	0.1777517	11	0.0487459	3	0.0714743	3	0	0	0.012362	1	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K17299|0|hsa:445582|POTEE, A26C1, A26C1A, CT104.2, POTE-2, POTE2, POTE2gamma; POTE ankyrin domain family, member E; K17299 POTE ankyrin domain family protein (A)"	--	[Z]	Cytoskeleton	Actin;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; CCDC144C protein coiled-coil region	POTE ankyrin domain family member E GN=POTEE OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	"PREDICTED: actin, cytoplasmic 1 [Camelus dromedarius]"
ENSG00000188227(ZNF793)	--	0.007919277	1	0.150566439	2	0.069566209	3	0.017922325	1	0.035839754	2	0.056956131	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:390927|ZNF793; zinc finger protein 793; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 793 GN=ZNF793 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 793 isoform X2 [Equus przewalskii]
ENSG00000188229(TUBB4B)	--	322.277	9326	268.951	7941	317.331	9428	355.522	10359	312.065	8987	235.134	6847	0.994856555	0.120703269	normal	0.992611523	0.157064219	normal	0.680429422	-0.469682392	normal	0.902758197	-0.049588027	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07375|0|xtr:779904|tubb4b, tubb2, tubb2c, tubb4; tubulin, beta 4B class IVb; K07375 tubulin beta (A)"	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta-4B chain GN=TUBB4B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tubulin beta-4B chain isoform X1 [Orycteropus afer afer]
ENSG00000188234(AGAP4)	--	4.75077537	207	6.808662417	204	8.285437686	244	7.032738245	246	5.463780593	247	6.19629914	235	0.943147116	0.216718377	normal	0.929912774	0.252809998	normal	0.965547718	-0.06211949	normal	0.731192624	0.131452286	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; PH domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Pleckstrin homology domain;; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 GN=AGAP5 OS=Homo sapiens (Human) PE=2 SV=2"	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X2 [Eptesicus fuscus]"
ENSG00000188243(COMMD6)	--	20.24999115	368	35.02512103	436	24.176731	461	31.03337129	536	30.78458106	493	20.17787054	413	0.378467315	0.509921771	normal	0.957622278	0.155326068	normal	0.955656812	-0.166339587	normal	0.530227085	0.167202845	normal	--	--	--	--	--	--	--	HCaRG protein	COMM domain-containing protein 6 GN=COMMD6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: COMM domain-containing protein 6 [Pteropus alecto]
ENSG00000188257(PLA2G2A)	--	0	0	0.0609139	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipase A2 activity (GO:0004623);; Biological Process: phospholipid metabolic process (GO:0006644);; Biological Process: arachidonic acid secretion (GO:0050482);; 	"K01047|1.53475e-87|hsa:5320|PLA2G2A, MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2; phospholipase A2, group IIA (platelets, synovial fluid) (EC:3.1.1.4); K01047 secretory phospholipase A2 [EC:3.1.1.4] (A)"	Glycerophospholipid metabolism (ko00564);; Ether lipid metabolism (ko00565);; Arachidonic acid metabolism (ko00590);; Linoleic acid metabolism (ko00591);; alpha-Linolenic acid metabolism (ko00592);; Ras signaling pathway (ko04014);; Vascular smooth muscle contraction (ko04270);; Pancreatic secretion (ko04972);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Phospholipase A2	"Phospholipase A2, membrane associated (Precursor) GN=PLA2G2A OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: phospholipase A2, membrane associated [Galeopterus variegatus]"
ENSG00000188263(IL17REL)	--	0.087743822	6	0.042866412	3	0	0	0.014715172	1	0.042660495	2	0.028854723	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Interleukin-17 receptor extracellular region	Putative interleukin-17 receptor E-like GN=IL17REL OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: putative interleukin-17 receptor E-like [Ceratotherium simum simum]
ENSG00000188266(HYKK)	--	8.118330057	160	6.308359841	156	6.278652719	166	4.25600355	98	3.93396	86	3.8180254	82	0.211093205	-0.729010423	normal	0.049905385	-0.869045432	normal	0.004995547	-1.012385471	down	0.005233572	-0.879271072	normal	[R]	General function prediction only	--	"K18201|0|hsa:123688|HYKK, AGPHD1; hydroxylysine kinase (EC:2.7.1.81); K18201 hydroxylysine kinase [EC:2.7.1.81] (A)"	Lysine degradation (ko00310)	--	--	Phosphotransferase enzyme family	Hydroxylysine kinase GN=HYKK OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: hydroxylysine kinase isoform X2 [Physeter catodon]
ENSG00000188277(C15orf62)	--	0.871659	44	0.348246	18	0.532757	27	0.296317	15	0.752376	38	0.783695	40	0.097019545	-1.490251015	normal	0.779661769	0.997732318	normal	0.95642582	0.534034108	normal	0.985893701	0.044813773	normal	--	--	--	--	--	--	--	Cdc42 effector	"Uncharacterized protein C15orf62, mitochondrial (Precursor) GN=C15orf62 OS=Homo sapiens (Human) PE=2 SV=1"	S	Function unknown	"PREDICTED: uncharacterized protein C15orf62 homolog, mitochondrial [Camelus bactrianus] "
ENSG00000188283(ZNF383)	--	4.104165949	228	3.756652185	202	4.327562268	207	3.860919979	232	4.598188075	239	4.101599493	257	0.966998691	-0.005703184	normal	0.941313612	0.219715108	normal	0.906072237	0.301863329	normal	0.63377973	0.171722258	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:163087|ZNF383; zinc finger protein 383; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain;; Zinc ribbon domain;; XPA protein N-terminal;; BED zinc finger"	Zinc finger protein 383 GN=ZNF383 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: uncharacterized protein LOC100052230 [Equus caballus]
ENSG00000188290(HES4)	--	14.06671	182	11.82222	151	10.99802894	161	17.187337	224	15.59267	197	13.46428	179	0.928150705	0.26669577	normal	0.88035773	0.359064109	normal	0.959711048	0.143330108	normal	0.475738105	0.258547768	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K09089|3.30869e-94|hsa:57801|HES4, bHLHb42; hes family bHLH transcription factor 4; K09089 hairy and enhancer of split 4 (A)"	--	[K]	Transcription	Hairy Orange;; Helix-loop-helix DNA-binding domain	Transcription factor HES-4 GN=HES4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor HES-4 [Leptonychotes weddellii]
ENSG00000188293(IGFL1)	--	0.300507	3	0	0	0.289009	2	0.861495	9	1.36819	13	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Insulin growth factor-like family	Insulin growth factor-like family member 1 (Precursor) GN=IGFL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: insulin growth factor-like family member 1-like [Equus caballus]
ENSG00000188295(ZNF669)	--	3.78132905	176	2.556716049	132	2.581438157	143	2.780541188	162	2.9946627	134	2.867453822	148	0.959106172	-0.149057023	normal	0.967247498	0.000265494	normal	0.967485994	0.040865764	normal	0.946007535	-0.044181542	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101151976|ZNF669; zinc finger protein 669; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 669 GN=ZNF669 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 709-like [Leptonychotes weddellii]
ENSG00000188305(C19orf35)	--	0.0257529	1	0	0	0	0	0	0	0.0249278	0	0.101339	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative uncharacterized protein C19orf35 GN=C19orf35 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: putative uncharacterized protein C19orf35 homolog [Sus scrofa]
ENSG00000188312(CENPP)	--	3.029098	173	3.89653	165	2.030023	156	3.366612	165	4.8560473	153	4.314492	194	0.964011518	-0.098244704	normal	0.960399675	-0.129131475	normal	0.916696957	0.30357533	normal	0.963294031	0.030758971	normal	--	--	"Cellular Component: chromosome, centromeric region (GO:0000775);; Biological Process: CENP-A containing nucleosome assembly (GO:0034080);; "	"K11508|0|hsa:401541|CENPP, CENP-P; centromere protein P; K11508 centromere protein P (A)"	--	--	--	"CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P"	Centromere protein P GN=CENPP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein P [Ceratotherium simum simum]
ENSG00000188313(PLSCR1)	--	21.69721686	601	21.166403	628	22.90889806	661	41.94491	1195	42.34126376	1199	39.1649887	1164	4.38E-06	0.958970729	normal	2.93E-05	0.909956398	normal	0.000436448	0.806668496	normal	9.63E-10	0.891547123	normal	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Scramblase	Phospholipid scramblase 1 GN=PLSCR1 OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: phospholipid scramblase 1 [Echinops telfairi]
ENSG00000188316(ENO4)	--	0.269612	11	0.1010994	5	0	0	0.2117231	7	0.190057	7	0.337236902	15	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	--	--	--	[G]	Carbohydrate transport and metabolism	"Enolase, C-terminal TIM barrel domain;; Enolase, N-terminal domain"	Enolase-like protein ENO4 GN=ENO4 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: enolase-like protein ENO4 [Galeopterus variegatus]
ENSG00000188321(ZNF559)	--	5.919369688	159	6.191600516	186	5.468297869	139	5.58029843	192	3.972930735	127	5.721786802	176	0.941140183	0.239142021	normal	0.547430873	-0.566292912	normal	0.90881889	0.329011089	normal	0.989936683	0.010361935	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:84527|ZNF559, NBLA00121; zinc finger protein 559; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal"	Zinc finger protein 559 GN=ZNF559 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 559-like [Trichechus manatus latirostris]
ENSG00000188322(SBK1)	--	1.299109653	126	1.101343	105	1.111453	109	0.536151	51	0.846583	81	0.6929	67	0.000348313	-1.309714287	down	0.914308404	-0.389417086	normal	0.527117473	-0.697915322	normal	0.035694961	-0.793112836	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08858|0|hsa:388228|SBK1, SBK; SH3 domain binding kinase 1 (EC:2.7.11.1); K08858 serine/threonine-protein kinase SBK [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase SBK1 GN=SBK1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase SBK1 [Odobenus rosmarus divergens]
ENSG00000188338(SLC38A3)	--	0.020778608	1	0	0	0	0	0	0	0.081818539	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13576|0|hsa:10991|SLC38A3, G17, NAT1, SN1, SNAT3; solute carrier family 38, member 3; K13576 solute carrier family 38 (sodium-coupled neutral amino acid transporter), member 3 (A)"	Glutamatergic synapse (ko04724);; GABAergic synapse (ko04727);; Proximal tubule bicarbonate reclamation (ko04964)	[E]	Amino acid transport and metabolism	Transmembrane amino acid transporter protein	Sodium-coupled neutral amino acid transporter 3 OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: sodium-coupled neutral amino acid transporter 3 isoform X2 [Canis lupus familiaris] 
ENSG00000188342(GTF2F2)	--	25.8000565	616	19.21991299	481	22.13990697	558	22.41428458	562	19.42833047	503	18.44694517	401	0.959376562	-0.162767237	normal	0.970059529	0.042962856	normal	0.466775112	-0.483401649	normal	0.471756611	-0.197033637	normal	[K]	Transcription	Cellular Component: transcription factor TFIIF complex (GO:0005674);; Biological Process: transcription from RNA polymerase II promoter (GO:0006366);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	"K03139|0|ptr:741868|GTF2F2; general transcription factor IIF, polypeptide 2, 30kDa; K03139 transcription initiation factor TFIIF subunit beta [EC:3.6.4.12] (A)"	Basal transcription factors (ko03022)	[K]	Transcription	"Transcription initiation factor IIF, beta subunit"	General transcription factor IIF subunit 2 GN=GTF2F2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: general transcription factor IIF subunit 2 [Equus caballus] 
ENSG00000188343(FAM92A)	--	15.5010592	402	16.39502223	428	17.58600352	423	15.12826296	371	13.33119469	365	14.20904131	374	0.95853019	-0.146027383	normal	0.925819471	-0.250182471	normal	0.950525829	-0.185206174	normal	0.468640068	-0.195975408	normal	--	--	--	--	--	--	--	FAM92 protein	Protein FAM92A1 GN=FAM92A1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM92A1 isoform X5 [Loxodonta africana]
ENSG00000188352(FOCAD)	--	15.28469715	1596	15.72485961	1690	14.73703136	1530	21.6248385	2273	22.61297224	2270	18.336924	1915	0.4437102	0.478916674	normal	0.760221487	0.403929604	normal	0.906546556	0.315242229	normal	0.008010046	0.401461691	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3028);; Protein of unknown function (DUF3730)	Focadhesin GN=FOCAD OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: focadhesin [Ceratotherium simum simum]
ENSG00000188368(PRR19)	--	3.90513	110	3.30659	93	4.130178	117	2.923776	81	2.3361148	66	3.5167143	100	0.869176837	-0.464744776	normal	0.863828252	-0.50636696	normal	0.954232381	-0.231559056	normal	0.378310302	-0.393894986	normal	--	--	--	--	--	--	--	Proline-rich 19	Proline-rich protein 19 GN=PRR19 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: proline-rich protein 19 [Ceratotherium simum simum]
ENSG00000188372(ZP3)	--	11.73781204	324	10.90628519	300	11.88776035	330	8.172688936	225	10.46543066	286	9.721271756	269	0.354838308	-0.553730782	normal	0.963130183	-0.089909657	normal	0.897887798	-0.30161757	normal	0.240424421	-0.310990944	normal	--	--	--	--	--	--	--	Zona pellucida-like domain	Processed zona pellucida sperm-binding protein 3 (Precursor) GN=ZP3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: zona pellucida sperm-binding protein 3 [Tupaia chinensis]
ENSG00000188385(JAKMIP3)	--	1.87616021	278	2.084994731	302	2.012334598	315	1.5568702	234	1.865912	277	2.06073	314	0.916847909	-0.277733019	normal	0.956486578	-0.145328953	normal	0.968059605	-0.01281708	normal	0.682408658	-0.13765101	normal	--	--	--	--	--	--	--	--	Janus kinase and microtubule-interacting protein 3 GN=JAKMIP3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: janus kinase and microtubule-interacting protein 3 [Tupaia chinensis]
ENSG00000188389(PDCD1)	--	0	0	0.026629819	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06744|4.27999e-175|mcc:100135775|PDCD1, PD1; programmed cell death 1; K06744 programmed cell death protein 1 (A)"	Cell adhesion molecules (CAMs) (ko04514);; T cell receptor signaling pathway (ko04660)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain	Programmed cell death protein 1 (Precursor) GN=PDCD1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: programmed cell death protein 1 isoform 2 [Ceratotherium simum simum]
ENSG00000188396(TCTEX1D4)	--	1.01255	8	0.717335	6	1.40071	11	0.860883	7	2.31363	18	4.23607	34	--	--	--	--	--	--	0.314647344	1.497358891	normal	--	--	--	--	--	--	--	--	[N]	Cell motility	Tctex-1 family	Tctex1 domain-containing protein 4 GN=TCTEX1D4 OS=Homo sapiens (Human) PE=1 SV=1	N	Cell motility	PREDICTED: tctex1 domain-containing protein 4 [Galeopterus variegatus]
ENSG00000188404(SELL)	--	0	0	0.0219024	1	0	0	0.0657687	3	0.0215217	0	0.109691	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06495|0|hsa:6402|SELL, CD62L, LAM1, LECAM1, LEU8, LNHR, LSEL, LYAM1, PLNHR, TQ1; selectin L; K06495 selectin, lymphocyte (A)"	Cell adhesion molecules (CAMs) (ko04514)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; Sushi domain (SCR repeat);; EGF-like domain	L-selectin (Precursor) GN=SELL OS=Homo sapiens (Human) PE=1 SV=2	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: L-selectin [Galeopterus variegatus]
ENSG00000188419(CHM)	--	9.87414	804	11.78182	922	10.91794	854	9.45176	765	8.91222	716	9.85098	753	0.972125405	-0.102367433	normal	0.763756773	-0.385514052	normal	0.95759154	-0.189519984	normal	0.246622898	-0.229051955	normal	--	--	Molecular Function: GDP-dissociation inhibitor activity (GO:0005092);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	GDP dissociation inhibitor	Rab proteins geranylgeranyltransferase component A 1 GN=CHM OS=Homo sapiens (Human) PE=1 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab proteins geranylgeranyltransferase component A 1 [Ceratotherium simum simum]
ENSG00000188425(NANOS2)	--	0	0	0	0	0.0713154	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K18760|4.49474e-78|ptr:745748|NANOS2; nanos homolog 2 (Drosophila); K18760 protein nanos 2 (A)	--	[R]	General function prediction only	Nanos RNA binding domain	Nanos homolog 2 GN=NANOS2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nanos homolog 2 [Pantholops hodgsonii]
ENSG00000188428(BLOC1S5)	--	4.464597325	205	4.6431522	213	4.65513696	191	4.698201119	218	4.3517103	198	5.140335567	236	0.965710506	0.057454373	normal	0.959320632	-0.125852514	normal	0.913243364	0.29481914	normal	0.867131421	0.077264863	normal	--	--	Cellular Component: transport vesicle (GO:0030133);; Cellular Component: BLOC-1 complex (GO:0031083);; 	--	--	--	--	"Organelle biogenesis, Muted-like protein"	Biogenesis of lysosome-related organelles complex 1 subunit 5 GN=BLOC1S5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: biogenesis of lysosome-related organelles complex 1 subunit 5 isoform X2 [Tupaia chinensis]
ENSG00000188452(CERKL)	--	2.068144695	98	1.460845431	68	1.992563074	94	0.938316282	42	1.449458234	65	0.71603223	36	0.006758638	-1.223050948	down	0.973020647	-0.084597035	normal	0.002031131	-1.356381756	down	0.03704158	-0.883494362	normal	--	--	Molecular Function: kinase activity (GO:0016301);; 	--	--	[IT]	Lipid transport and metabolism;; Signal transduction mechanisms	Diacylglycerol kinase catalytic domain	Ceramide kinase-like protein GN=CERKL OS=Homo sapiens (Human) PE=1 SV=1	IT	Lipid transport and metabolism;; Signal transduction mechanisms	PREDICTED: ceramide kinase-like protein [Tupaia chinensis]
ENSG00000188467(SLC24A5)	--	0	0	0.1654267	4	0	0	0.0289109	1	0.0518168	0	0.1392137	4	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K13753|0|hsa:283652|SLC24A5, JSX, NCKX5, OCA6, SHEP4; solute carrier family 24 (sodium/potassium/calcium exchanger), member 5; K13753 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5 (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Sodium/calcium exchanger protein	Sodium/potassium/calcium exchanger 5 (Precursor) GN=SLC24A5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/potassium/calcium exchanger 5 [Tupaia chinensis]
ENSG00000188483(IER5L)	--	134.706	5271	135.575	5454	101.88	4182	72.7432	2871	84.7622	3345	118.931	4739	6.43E-06	-0.906991483	normal	0.003494325	-0.726475111	normal	0.986730052	0.17203968	normal	0.156978892	-0.464518289	normal	--	--	--	--	--	--	--	Immediate early response protein (IER)	Immediate early response gene 5-like protein GN=IER5L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: immediate early response gene 5-like protein [Orcinus orca]
ENSG00000188486(H2AFX)	--	106.288	2386	94.5203	2164	109.899	2572	112.995	2581	110.437	2510	93.3818	2140	0.987125458	0.08245278	normal	0.975453027	0.192435349	normal	0.949640875	-0.273394794	normal	1	0.000443436	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.48288e-80|ptr:104001345|histone H2AX; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2AX GN=H2AFX OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A.x-like [Ochotona princeps]
ENSG00000188487(INSC)	--	0.03414125	1	0	0	0	0	0	0	0.031546057	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein inscuteable homolog GN=INSC OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein inscuteable homolog [Panthera tigris altaica]
ENSG00000188493(C19orf54)	--	12.900431	604	10.861606	496	13.560337	573	10.828872	504	11.898933	536	16.107265	758	0.899414311	-0.29114497	normal	0.967602885	0.090201725	normal	0.734370792	0.394463281	normal	0.861244838	0.084101011	normal	--	--	--	--	--	--	--	--	UPF0692 protein C19orf54 GN=C19orf54 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0692 protein C19orf54 homolog isoform X1 [Tupaia chinensis] 
ENSG00000188501(LCTL)	--	0.639542	32	0.5985771	28	1.14803	54	0.74617	35	0.3009734	15	0.64641	32	0.983459724	0.094128682	normal	0.930153065	-0.857672305	normal	0.836958488	-0.736108388	normal	0.525184117	-0.496042121	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 1	Lactase-like protein (Precursor) GN=LCTL OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: lactase-like [Canis lupus familiaris]
ENSG00000188505(NCCRP1)	--	0.0311155	1	0.122981	4	0.180689	5	0.186628	6	0.302223	9	0.0923954	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	F-box associated region	F-box only protein 50 GN=NCCRP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: F-box only protein 50 [Ceratotherium simum simum]
ENSG00000188517(COL25A1)	--	0	0	0.010485146	1	0	0	0	0	0.028463132	1	0.021356178	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	Collagen-like Alzheimer amyloid plaque component OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(XXV) chain [Orycteropus afer afer]
ENSG00000188522(FAM83G)	--	12.86312838	1452	13.86607474	1573	12.50679272	1432	17.98668655	2020	18.69347817	2101	16.78786052	1902	0.586417328	0.445080707	normal	0.776398678	0.395800653	normal	0.743753754	0.400825837	normal	0.006244606	0.412965781	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1669);; PLD-like domain	Protein FAM83G GN=FAM83G OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM83G [Ceratotherium simum simum]
ENSG00000188523(CFAP77)	--	0	0	0	0	0.0699624	0	0	0	0	0	0.072921877	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4483)	Uncharacterized protein C9orf171 GN=C9orf171 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf171 homolog [Ceratotherium simum simum]
ENSG00000188529(SRSF10)	--	45.234162	1786	51.450341	2073	52.8508924	2074	52.74208541	2073	44.93829187	1748	44.71463747	1734	0.97398753	0.184008746	normal	0.947421141	-0.267228893	normal	0.947053943	-0.266390702	normal	0.585518535	-0.116660458	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K12900|3.77678e-87|cjc:100387136|SRSF10; serine/arginine-rich splicing factor 10; K12900 FUS-interacting serine-arginine-rich protein 1 (A)	Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Serine/arginine-rich splicing factor 10 GN=SRSF10 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 10 isoform X1 [Camelus dromedarius]
ENSG00000188542(DUSP28)	--	4.62217	157	5.50568	199	4.49095	161	2.566524	87	2.7407	91	2.50685	98	0.045096275	-0.870886283	normal	0.00022741	-1.137144365	down	0.239793949	-0.715792078	normal	0.002249087	-0.926551079	normal	--	--	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K14165|2.87717e-111|hsa:285193|DUSP28, DUSP26, VHP; dual specificity phosphatase 28 (EC:3.1.3.16 3.1.3.48); K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain"	Dual specificity phosphatase 28 GN=DUSP28 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: dual specificity phosphatase 28 [Odobenus rosmarus divergens]
ENSG00000188549(C15orf52)	--	7.014011587	855	7.02679123	885	11.16885177	908	10.82459413	1290	8.808453008	1063	8.938836031	1039	0.130766806	0.561715525	normal	0.941846345	0.242587006	normal	0.961787008	0.185850445	normal	0.046397282	0.335395227	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4594)	Uncharacterized protein C15orf52 GN=C15orf52 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C15orf52 homolog [Galeopterus variegatus]
ENSG00000188554(NBR1)	--	30.3531373	2687	26.674543	2327	33.37855253	2783	33.73256275	3133	31.50418468	2813	34.89751621	3134	0.979244731	0.190615176	normal	0.961862616	0.252062607	normal	0.983131196	0.162989323	normal	0.276762493	0.198756036	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; 	K17987|0|pps:100977780|NBR1; neighbor of BRCA1 gene 1; K17987 next to BRCA1 gene 1 protein (A)	--	[S]	Function unknown	"PB1 domain;; Zinc finger, ZZ type"	Next to BRCA1 gene 1 protein GN=NBR1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: next to BRCA1 gene 1 protein isoform X1 [Galeopterus variegatus] 
ENSG00000188559(RALGAPA2)	--	6.204551914	932	4.543228758	805	5.832027884	839	5.216075158	755	4.603834057	741	6.31531327	929	0.856202048	-0.334072333	normal	0.966672178	-0.140666263	normal	0.969469364	0.138479045	normal	0.655161939	-0.107767439	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	--	--	[T]	Signal transduction mechanisms	Rap/ran-GAP	Ral GTPase-activating protein subunit alpha-2 GN=RALGAPA2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ral GTPase-activating protein subunit alpha-2 [Ceratotherium simum simum]
ENSG00000188566(NDOR1)	--	11.0977669	1040	10.5491502	1024	11.81003451	1148	10.1246445	958	10.95214823	1044	10.9305634	1018	0.96954175	-0.149088647	normal	0.979463976	0.006469976	normal	0.964702553	-0.181422563	normal	0.632235429	-0.10970108	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: FMN binding (GO:0010181);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[C]	Energy production and conversion	FAD binding domain;; Flavodoxin;; Oxidoreductase NAD-binding domain	NADPH-dependent diflavin oxidoreductase 1 {ECO:0000255|HAMAP-Rule:MF_03178} OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADPH-dependent diflavin oxidoreductase 1 isoform 1 [Ceratotherium simum simum]
ENSG00000188573(FBLL1)	--	0.17956	4	0.126677	3	0.122567	2	0.130062	3	0.172349	3	0.0435559	1	--	--	--	--	--	--	--	--	--	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Biological Process: rRNA processing (GO:0006364);; Biological Process: tRNA processing (GO:0008033);; Molecular Function: methyltransferase activity (GO:0008168);; 	K14563|0|nle:100593582|rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1-like; K14563 rRNA 2'-O-methyltransferase fibrillarin [EC:2.1.1.-] (A)	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	Fibrillarin	rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 GN=FBLL1 OS=Homo sapiens (Human) PE=3 SV=1	A	RNA processing and modification	"PREDICTED: rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1-like, partial [Physeter catodon]"
ENSG00000188580(NKAIN2)	--	0.021331763	1	0.043105638	2	0.064181108	2	0.021141857	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	"Na,K-Atpase Interacting protein"	Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 GN=NKAIN2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: sodium/potassium-transporting ATPase subunit beta-1-interacting protein 2 [Monodelphis domestica]
ENSG00000188581(KRTAP1-1)	--	0	0	0	0	0	0	0.0917531	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: keratin filament (GO:0045095);; 	--	--	[W]	Extracellular structures	"Keratin, high sulfur B2 protein;; Keratin, high sulfur B2 protein"	Keratin-associated protein 1-1 GN=KRTAP1-1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: keratin-associated protein 1-3-like [Elephantulus edwardii]
ENSG00000188582(PAQR9)	--	1.22646	41	0.653882	22	0.65716	22	1.11861	38	1.19928	40	1.17573	40	0.980668681	-0.135192585	normal	0.883960599	0.799776344	normal	0.881637516	0.812249749	normal	0.520566137	0.451776328	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[RT]	General function prediction only;; Signal transduction mechanisms	Haemolysin-III related	Progestin and adipoQ receptor family member 9 GN=PAQR9 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: progestin and adipoQ receptor family member 9 isoform X1 [Sus scrofa]
ENSG00000188596(CFAP54)	--	0.514239024	38	0.363780978	27	0.4092438	18	0.281751204	40	0.472215385	41	0.59870018	33	0.982076179	0.0415316	normal	0.949637523	0.555818878	normal	0.920540227	0.814938697	normal	0.543659221	0.435307777	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4486)	Putative uncharacterized protein C12orf63 GN=C12orf63 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein CFAP54 isoform X4 [Bos taurus] 
ENSG00000188603(CLN3)	--	32.33539543	862	38.67350597	976	34.03809489	898	31.67463942	823	28.8263339	737	50.87927976	1308	0.973513259	-0.09744991	normal	0.648159437	-0.425880957	normal	0.208894084	0.533535018	normal	0.949106958	0.048103241	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K12389|0|hsa:1201|CLN3, BTS, JNCL; ceroid-lipofuscinosis, neuronal 3; K12389 battenin (A)"	Lysosome (ko04142)	[R]	General function prediction only	CLN3 protein	Battenin (Precursor) GN=CLN3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: battenin isoformX2 [Equus caballus]
ENSG00000188610(FAM72B)	--	4.862512006	174	4.919328936	189	6.414583	246	5.089654622	196	3.456831986	119	4.199134	149	0.959539933	0.139770801	normal	0.237470118	-0.681910871	normal	0.075897948	-0.725843332	normal	0.259961227	-0.414049862	normal	--	--	--	--	--	--	--	FAM72 protein	Protein FAM72B GN=FAM72B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM72A [Canis lupus familiaris]
ENSG00000188611(ASAH2)	--	1.125161704	58	0.778272288	61	0.528594649	40	0.785852707	64	1.062252584	71	0.642209196	50	0.975142269	0.108451253	normal	0.968094049	0.193141728	normal	0.970272115	0.303359464	normal	0.780392186	0.196062957	normal	--	--	--	K12349|0|ptr:450461|ASAH2; N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2; K12349 neutral ceramidase [EC:3.5.1.23] (A)	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[T]	Signal transduction mechanisms	Neutral/alkaline non-lysosomal ceramidase	Neutral ceramidase soluble form GN=ASAH2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neutral ceramidase [Ursus maritimus]
ENSG00000188612(SUMO2)	--	309.4266694	6113	281.8702281	5735	305.860414	6211	436.7795033	8569	407.0583119	8402	280.4975897	5838	0.720403408	0.45631675	normal	0.392024931	0.529396763	normal	0.993069714	-0.097618278	normal	0.238557037	0.314779676	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K12160|3.63262e-65|ssc:397044|SUMO2, PSMT3, SMT3H2, Smt3A; SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); K12160 small ubiquitin-related modifier (A)"	RNA transport (ko03013)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin family	Small ubiquitin-related modifier 2 {ECO:0000305} (Precursor) OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: small ubiquitin-related modifier 2 [Monodelphis domestica]
ENSG00000188613(NANOS1)	--	1.12838	69	1.11042	69	1.03413	64	0.69432	43	1.17999	73	0.788887	49	0.784184767	-0.693346749	normal	0.972765625	0.058624307	normal	0.951916715	-0.383202766	normal	0.600651479	-0.312629183	normal	--	--	--	"K18741|2.57699e-87|hsa:340719|NANOS1, NOS1, SPGF12; nanos homolog 1 (Drosophila); K18741 protein nanos 1 (A)"	--	[R]	General function prediction only	Nanos RNA binding domain	Nanos homolog 1 GN=NANOS1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: nanos homolog 1 [Odobenus rosmarus divergens]
ENSG00000188624(IGFL3)	--	0.651824	10	0.952797	9	0.3703482	6	4.14841	61	5.40926	74	9.12313	96	5.55E-06	2.410095942	up	5.88E-09	2.824964448	up	2.55E-15	3.690867307	up	3.13E-11	3.187341164	up	--	--	--	--	--	--	--	Insulin growth factor-like family	Insulin growth factor-like family member 3 (Precursor) GN=IGFL3 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: insulin growth factor-like family member 3 isoform X1 [Mustela putorius furo]
ENSG00000188626(GOLGA8M)	--	0.0611707	3	0	0	0	0	0.0404975	2	0.0395598	1	0.0605783	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8M OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000188636(LDOC1L)	--	14.6719	1465	14.1022	1431	13.1287	1324	12.0511	1199	12.2185	1208	9.97058	995	0.890703313	-0.3195301	normal	0.93762455	-0.265523941	normal	0.661016062	-0.419870965	normal	0.041865243	-0.332698145	normal	--	--	--	--	--	--	--	--	Protein LDOC1L GN=LDOC1L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein LDOC1L [Ursus maritimus]
ENSG00000188641(DPYD)	--	3.118501691	171	1.588261021	94	2.299551272	125	10.866181	697	11.019208	733	7.48066766	478	0	1.986772962	up	0	2.921793474	up	0	1.914061452	up	1.27E-10	2.26841306	up	[F]	Nucleotide transport and metabolism	"Cellular Component: cytoplasm (GO:0005737);; Biological Process: tRNA processing (GO:0008033);; Molecular Function: oxidoreductase activity (GO:0016491);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: tRNA dihydrouridine synthase activity (GO:0017150);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00207|0|hsa:1806|DPYD, DHP, DHPDHASE, DPD; dihydropyrimidine dehydrogenase (EC:1.3.1.2); K00207 dihydropyrimidine dehydrogenase (NADP+) [EC:1.3.1.2] (A)"	Pyrimidine metabolism (ko00240);; beta-Alanine metabolism (ko00410);; Pantothenate and CoA biosynthesis (ko00770);; Drug metabolism - other enzymes (ko00983)	[F]	Nucleotide transport and metabolism	"Dihydroorotate dehydrogenase;; Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster;; 4Fe-4S dicluster domain;; Dihydrouridine synthase (Dus);; NAD(P)-binding Rossmann-like domain;; Pyridine nucleotide-disulphide oxidoreductase"	Dihydropyrimidine dehydrogenase [NADP(+)] (Precursor) GN=DPYD OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: dihydropyrimidine dehydrogenase [NADP(+)] [Condylura cristata]
ENSG00000188643(S100A16)	--	107.4972823	1831	106.4928253	1838	118.7109287	2063	233.44761	3963	210.3637792	3531	150.5332755	2580	8.02E-09	1.082496919	up	7.37E-06	0.919958101	normal	0.920442454	0.314129483	normal	0.00305713	0.791334342	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	EF-hand domain pair;; S-100/ICaBP type calcium binding domain	Protein S100-A16 GN=S100A16 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein S100-A16 isoform X1 [Myotis brandtii] 
ENSG00000188647(PTAR1)	--	9.858666498	1280	11.02371216	1459	10.11806859	1288	14.11045904	1864	14.4247319	1877	13.56000898	1829	0.291270132	0.51091494	normal	0.876200103	0.341709216	normal	0.349657267	0.497138782	normal	0.00280047	0.446601223	normal	--	--	Molecular Function: protein prenyltransferase activity (GO:0008318);; Biological Process: protein prenylation (GO:0018342);; 	K14137|0|hsa:375743|PTAR1; protein prenyltransferase alpha subunit repeat containing 1; K14137 protein prenyltransferase alpha subunit repeat containing protein 1 (A)	--	--	--	Protein prenyltransferase alpha subunit repeat	Protein prenyltransferase alpha subunit repeat-containing protein 1 GN=PTAR1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein prenyltransferase alpha subunit repeat-containing protein 1 [Trichechus manatus latirostris]
ENSG00000188649(CC2D2B)	--	0.228926306	4	0	0	0	0	0.0741904	1	0.1454428	2	0.21987996	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	Protein CC2D2B GN=CC2D2B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein CC2D2B [Equus przewalskii]
ENSG00000188659(SAXO2)	--	0.861407631	10	1.075169923	17	3.119391086	19	0.6101465	5	2.59853982	13	1.406173095	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	STOP protein	Protein FAM154B GN=FAM154B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	Protein FAM154B [Tupaia chinensis]
ENSG00000188672(RHCE)	--	0.057412286	1	0.0840474	1	0	0	0.0418496	1	0.0558072	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ammonium transmembrane transporter activity (GO:0008519);; Biological Process: ammonium transport (GO:0015696);; Cellular Component: membrane (GO:0016020);; 	"K06579|0|hsa:6006|RHCE, CD240CE, RH, RH30A, RHC, RHE, RHIXB, RHPI, Rh4, RhIVb(J), RhVI, RhVIII; Rh blood group, CcEe antigens; K06579 Rhesus blood group glycoprotein (A)"	--	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Ammonium Transporter Family	Blood group Rh(CE) polypeptide GN=RHCE OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: RH-like protein isoform X2 [Myotis brandtii]
ENSG00000188676(IDO2)	--	0.156097682	3	0	0	0	0	0	0	0.050837387	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: heme binding (GO:0020037);; 	"K00463|0|hsa:169355|IDO2, INDOL1; indoleamine 2,3-dioxygenase 2 (EC:1.13.11.52); K00463 indoleamine 2,3-dioxygenase [EC:1.13.11.52] (A)"	Tryptophan metabolism (ko00380);; African trypanosomiasis (ko05143)	--	--	"Indoleamine 2,3-dioxygenase"	"Indoleamine 2,3-dioxygenase 2 GN=IDO2 OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: indoleamine 2,3-dioxygenase 2 [Trichechus manatus latirostris]"
ENSG00000188687(SLC4A5)	--	1.591614426	181	1.602034815	187	1.239260924	140	0.853594125	106	1.05024501	109	1.650282136	184	0.07272452	-0.793840922	normal	0.071343549	-0.79164578	normal	0.868917182	0.382374075	normal	0.420010221	-0.3684404	normal	--	--	Biological Process: anion transport (GO:0006820);; Molecular Function: anion transmembrane transporter activity (GO:0008509);; Cellular Component: integral component of membrane (GO:0016021);; 	"K13857|0|hsa:57835|SLC4A5, NBC4; solute carrier family 4 (sodium bicarbonate cotransporter), member 5; K13857 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 (A)"	Bile secretion (ko04976)	[P]	Inorganic ion transport and metabolism	HCO3- transporter family;; Band 3 cytoplasmic domain	Electrogenic sodium bicarbonate cotransporter 4 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: electrogenic sodium bicarbonate cotransporter 4 [Galeopterus variegatus]
ENSG00000188690(UROS)	--	37.6973961	1039	37.99127005	996	42.05353589	1129	45.70744479	1239	45.01534275	1195	40.7507557	1125	0.953321179	0.222846208	normal	0.945272518	0.241031918	normal	0.98091662	-0.013393954	normal	0.480878501	0.14844734	normal	[H]	Coenzyme transport and metabolism	Molecular Function: uroporphyrinogen-III synthase activity (GO:0004852);; Biological Process: tetrapyrrole biosynthetic process (GO:0033014);; 	"K01719|0|hsa:7390|UROS, UROIIIS; uroporphyrinogen III synthase (EC:4.2.1.75); K01719 uroporphyrinogen-III synthase [EC:4.2.1.75] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	Uroporphyrinogen-III synthase HemD	Uroporphyrinogen-III synthase GN=UROS OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: uroporphyrinogen-III synthase isoform X3 [Galeopterus variegatus] 
ENSG00000188706(ZDHHC9)	--	23.80287541	1362	21.4257666	1203	25.83569655	1333	30.74217293	1862	29.67141096	1739	31.59215671	1738	0.678532858	0.41988758	normal	0.320147377	0.509659088	normal	0.807678451	0.37408714	normal	0.004123111	0.432516157	normal	[R]	General function prediction only	--	"K16675|0|ocu:100339342|ZDHHC9; zinc finger, DHHC-type containing 9; K16675 palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC9 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC9 [Oryctolagus cuniculus]
ENSG00000188707(ZBED6CL)	--	0	0	0	0	0	0	0.017926	1	0.0175458	0	0.0534149	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	ZBED6 C-terminal-like protein GN=ZBED6CL OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: ZBED6 C-terminal-like protein [Galeopterus variegatus]
ENSG00000188710(QRFP)	--	0.0712429	2	0.4602735	2	0.705227	4	0	0	0	0	0.245393937	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: orexigenic neuropeptide QRFP receptor binding (GO:0031854);; 	--	--	--	--	Orexigenic neuropeptide Qrfp/P518	QRF-amide (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: orexigenic neuropeptide QRFP [Trichechus manatus latirostris]
ENSG00000188716(DUPD1)	--	0	0	0	0	0	0	0.105455	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	"K14165|1.44486e-149|hsa:338599|DUPD1, DUSP27, FMDSP; dual specificity phosphatase and pro isomerase domain containing 1 (EC:3.1.3.16 3.1.3.48); K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)"	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain"	Dual specificity phosphatase DUPD1 GN=DUPD1 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity phosphatase DUPD1 [Tupaia chinensis]
ENSG00000188725(SMIM15)	--	39.7013542	1354	40.278178	1426	42.14870238	1358	40.27596	1490	44.389528	1460	46.30742319	1509	0.979471881	0.107136414	normal	0.98319573	0.012554671	normal	0.975800049	0.143666049	normal	0.713277133	0.086575345	normal	--	--	--	--	--	--	--	Uncharacterised protein family UPF0542	Small integral membrane protein 15 GN=SMIM15 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0542 protein C5orf43 homolog [Sarcophilus harrisii] 
ENSG00000188732(FAM221A)	--	1.479203	18	1.54667	23	1.264663	19	0.77459302	14	1.5674813	29	1.180414645	20	--	--	--	0.981434248	0.295650606	normal	0.988910859	0.060978196	normal	0.985435375	0.050175022	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4475)	Protein FAM221A GN=FAM221A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM221A isoform X3 [Bubalus bubalis]
ENSG00000188735(TMEM120B)	--	8.95761	664	8.352890422	640	8.142505701	704	7.672000037	641	6.968590344	553	5.181877	458	0.971645132	-0.081499193	normal	0.937794016	-0.231629554	normal	0.055828411	-0.62683668	normal	0.129930858	-0.303596203	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	TMPIT-like protein	Transmembrane protein 120B GN=TMEM120B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	transmembrane protein 120B [Bos taurus] 
ENSG00000188738(FSIP2)	--	0.03855737	15	0.020938285	8	0.0104697	3	0.017891713	7	0.019818434	7	0.026524186	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Fibrous sheath-interacting protein 2 GN=FSIP2 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: fibrous sheath-interacting protein 2 [Ceratotherium simum simum]
ENSG00000188739(RBM34)	--	18.733342	695	18.0001023	688	18.6329277	726	18.38923804	650	19.228233	685	16.20173401	586	0.967220619	-0.12711486	normal	0.974288472	-0.027670181	normal	0.875696598	-0.316624742	normal	0.508742812	-0.156049567	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein 34 GN=RBM34 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: RNA-binding protein 34 [Bubalus bubalis]
ENSG00000188747(NOXA1)	--	4.996661854	324	3.985317973	245	3.570723315	230	2.807147057	188	2.876265917	185	2.964413842	168	0.007961789	-0.810978215	normal	0.779736759	-0.423662849	normal	0.730740551	-0.457926286	normal	0.023022867	-0.58437499	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	--	--	[T]	Signal transduction mechanisms	TPR repeat;; Tetratricopeptide repeat;; PB1 domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; SH3 domain;; Variant SH3 domain	NADPH oxidase activator 1 GN=NOXA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: NADPH oxidase activator 1 [Galeopterus variegatus]
ENSG00000188760(TMEM198)	--	0.892155	27	1.105472921	20	0.680051712	19	0.516420041	17	0.770790249	18	0.422205001	14	0.966698487	-0.651164872	normal	0.987898839	-0.160621173	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4203)	Transmembrane protein 198 GN=TMEM198 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 198 [Felis catus] 
ENSG00000188761(BCL2L15)	--	0.241054	4	0.119261	2	0.178004	2	0.9099124	15	1.52753542	25	1.3334305	22	--	--	--	0.007848367	2.89998189	up	0.037883441	2.736692982	normal	--	--	--	--	--	--	--	--	--	--	--	Bcl-2-like protein 15 GN=BCL2L15 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: bcl-2-like protein 15 [Equus caballus] 
ENSG00000188763(FZD9)	--	2.89113	96	2.22643	77	2.49729	88	1.51264	51	1.56422	52	0.944215	32	0.165571789	-0.922761	normal	0.85286998	-0.573965698	normal	0.001534036	-1.425429872	down	0.020218895	-0.973372733	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	K02842|0|ptr:472405|FZD9; frizzled class receptor 9; K02842 frizzled 9/10 (A)	Wnt signaling pathway (ko04310);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; Melanogenesis (ko04916);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; Basal cell carcinoma (ko05217)	[T]	Signal transduction mechanisms	Frizzled/Smoothened family membrane region;; Fz domain;; Slime mold cyclic AMP receptor	Frizzled-9 (Precursor) GN=FZD9 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: frizzled-9 [Pteropus alecto]
ENSG00000188766(SPRED3)	--	2.646773672	272	2.243909963	230	2.311790496	250	3.601941513	266	2.967341883	232	1.559099409	156	0.965702777	-0.062654767	normal	0.965886867	-0.008877496	normal	0.128556923	-0.683391215	normal	0.530575809	-0.224093177	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	"K04703|1.06521e-118|hsa:399473|SPRED3, Eve-3, spred-3; sprouty-related, EVH1 domain containing 3; K04703 sprouty-related, EVH1 domain-containing protein (A)"	Jak-STAT signaling pathway (ko04630)	[T]	Signal transduction mechanisms	Sprouty protein (Spry);; WH1 domain	"Sprouty-related, EVH1 domain-containing protein 3 GN=SPRED3 OS=Homo sapiens (Human) PE=2 SV=1"	T	Signal transduction mechanisms	"PREDICTED: sprouty-related, EVH1 domain-containing protein 3 isoform X3 [Canis lupus familiaris]"
ENSG00000188771(PLET1)	--	0	0	0	0	0	0	0.0530798	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Placenta-expressed transcript 1 protein (Precursor) GN=PLET1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: placenta-expressed transcript 1 protein [Galeopterus variegatus]
ENSG00000188779(SKOR1)	--	0.112154062	7	0.015675527	1	0.029643295	1	0.095067447	6	0.030568502	1	0.030195747	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: SMAD binding (GO:0046332);; 	--	--	--	--	SKI/SNO/DAC family;; c-SKI Smad4 binding domain	SKI family transcriptional corepressor 1 GN=SKOR1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: SKI family transcriptional corepressor 1 isoform X1 [Ochotona princeps]
ENSG00000188783(PRELP)	--	0.0174173	2	0.00875152	1	0	0	0	0	0.0168623	1	0.00859096	1	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	K08125|0|ptr:469649|PRELP; proline/arginine-rich end leucine-rich repeat protein; K08125 proline arginine-rich end leucine-rich repeat protein (A)	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeat;; Leucine Rich repeat;; Leucine rich repeat N-terminal domain	Prolargin (Precursor) GN=PRELP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: prolargin [Ailuropoda melanoleuca] 
ENSG00000188786(MTF1)	--	3.02024	437	3.28643	474	3.28057	468	2.96911	428	3.444	495	3.13832	454	0.968696653	-0.060639307	normal	0.96997549	0.040986943	normal	0.969845442	-0.051937269	normal	0.956254395	-0.02301508	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Metal regulatory transcription factor 1 GN=MTF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: metal regulatory transcription factor 1 isoform X1 [Galeopterus variegatus] 
ENSG00000188803(SHISA6)	--	0	0	0	0	0	0	0	0	0	0	0.00711079	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Wnt and FGF inhibitory regulator	Protein shisa-6 homolog (Precursor) GN=SHISA6 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	"PREDICTED: protein shisa-6 homolog isoform X2, partial [Bos taurus] "
ENSG00000188807(TMEM201)	--	7.742055664	489	7.68081044	510	8.094279327	579	7.359514727	499	7.817628509	484	6.830190614	427	0.971611412	-0.001621869	normal	0.966609239	-0.096622603	normal	0.594128672	-0.446256041	normal	0.46315558	-0.183770396	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function C-terminus (DUF2448);; Ima1 N-terminal domain	Transmembrane protein 201 GN=TMEM201 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 201 [Odobenus rosmarus divergens]
ENSG00000188811(NHLRC3)	--	7.733301849	343	10.71162543	471	9.598109019	413	8.101923739	367	7.729193011	358	9.777863499	435	0.966805562	0.06645144	normal	0.712213749	-0.41565797	normal	0.968294083	0.066345442	normal	0.748078302	-0.101752521	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	NHL repeat;; SMP-30/Gluconolaconase/LRE-like region	NHL repeat-containing protein 3 (Precursor) GN=NHLRC3 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NHL repeat-containing protein 3 [Tupaia chinensis]
ENSG00000188816(HMX2)	--	0.13539	3	0.0880104	2	0	0	0	0	0.08632	1	0.044006	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09349|3.55598e-180|hsa:3167|HMX2, H6L, Nkx5-2; H6 family homeobox 2; K09349 homeobox protein Nkx-5 (A)"	--	--	--	Homeobox domain	Homeobox protein HMX2 GN=HMX2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: homeobox protein HMX2 [Dasypus novemcinctus]
ENSG00000188818(ZDHHC11)	--	4.11849873	456	5.930925	602	5.18164	501	3.943304	417	3.816242	388	6.064548947	679	0.956961601	-0.159257305	normal	0.045963727	-0.65307242	normal	0.637245858	0.429192584	normal	0.889033249	-0.091013147	normal	--	--	--	"K18932|0|hsa:79844|ZDHHC11, ZNF399; zinc finger, DHHC-type containing 11 (EC:2.3.1.225); K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC11 GN=ZDHHC11 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC11 [Equus przewalskii] 
ENSG00000188820(FAM26F)	--	0.20513045	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Calcium homeostasis modulator	Protein FAM26F GN=FAM26F OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	hypothetical protein PANDA_013413 [Ailuropoda melanoleuca]
ENSG00000188827(SLX4)	--	3.683948162	664	3.124708533	571	3.311807549	618	3.129370074	571	2.886129557	523	3.902842097	695	0.930285917	-0.247905432	normal	0.960850464	-0.147697457	normal	0.961365057	0.160743586	normal	0.809125651	-0.071317562	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Biological Process: DNA repair (GO:0006281);; Molecular Function: 5'-flap endonuclease activity (GO:0017108);; Cellular Component: Slx1-Slx4 complex (GO:0033557);; 	"K10484|0|hsa:84464|SLX4, BTBD12, FANCP, MUS312; SLX4 structure-specific endonuclease subunit; K10484 structure-specific endonuclease subunit SLX4 (BTB/POZ domain-containing protein 12) (A)"	Fanconi anemia pathway (ko03460)	--	--	Slx4 endonuclease;; BTB/POZ domain	Structure-specific endonuclease subunit SLX4 GN=SLX4 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: structure-specific endonuclease subunit SLX4 [Galeopterus variegatus]
ENSG00000188833(ENTPD8)	--	1.025217429	33	0.311130618	12	0.4787115	17	0.081265526	3	0	0	0.107626	4	0.000311244	-2.953410432	down	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	"K01510|0|hsa:377841|ENTPD8, E-NTPDase, GLSR2492, NTPDase-8, UNQ2492; ectonucleoside triphosphate diphosphohydrolase 8 (EC:3.6.1.5); K01510 apyrase [EC:3.6.1.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Epstein-Barr virus infection (ko05169)	[F]	Nucleotide transport and metabolism	GDA1/CD39 (nucleoside phosphatase) family	Ectonucleoside triphosphate diphosphohydrolase 8 GN=ENTPD8 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: ectonucleoside triphosphate diphosphohydrolase 8 isoform 1 [Ceratotherium simum simum]
ENSG00000188846(RPL14)	--	357.5740417	6092	339.0815321	5822	346.9366629	5952	389.6005584	7046	372.6435236	6589	330.8224239	5773	0.989691064	0.179014263	normal	0.990553872	0.157079758	normal	0.993853445	-0.052331242	normal	0.678753436	0.097670673	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02875|3.66736e-79|hsa:9045|RPL14, CAG-ISL-7, CTG-B33, L14, RL14, hRL14; ribosomal protein L14; K02875 large subunit ribosomal protein L14e (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L14	60S ribosomal protein L14 GN=RPL14 OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L14 [Galeopterus variegatus]
ENSG00000188848(BEND4)	--	0.046646371	2	0.008260566	1	0	0	0.008232739	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	BEN domain	BEN domain-containing protein 4 GN=BEND4 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: BEN domain-containing protein 4 [Chrysochloris asiatica]
ENSG00000188859(FAM78B)	--	0.036124323	1	0.141040236	4	0.034370268	0	0.142381815	4	0.31556195	8	0.106635585	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM78B GN=FAM78B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM78B [Chrysochloris asiatica]
ENSG00000188868(ZNF563)	--	0	0	0	0	0	0	0	0	0.302100126	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:147837|ZNF563; zinc finger protein 563; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 563 GN=ZNF563 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 564-like isoform X3 [Galeopterus variegatus]
ENSG00000188869(TMC3)	--	0	0	0.01033168	1	0	0	0	0	0	0	0.01027378	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	TMC domain	Transmembrane channel-like protein 3 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane channel-like protein 3 [Loxodonta africana]
ENSG00000188878(FBF1)	--	6.897315297	640	5.248033227	567	6.563416	674	5.046087407	473	4.674066919	477	6.029469055	609	0.51015466	-0.465757736	normal	0.915548479	-0.269999761	normal	0.96233867	-0.154233572	normal	0.156423173	-0.291099644	normal	--	--	--	"K16471|0|hsa:85302|FBF1, Alb, FBF-1; Fas (TNFRSF6) binding factor 1; K16471 Fas-binding factor 1 (A)"	--	--	--	--	Fas-binding factor 1 GN=FBF1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: fas-binding factor 1 [Ceratotherium simum simum]
ENSG00000188883(KLRG2)	--	0.472917092	16	0.251932651	11	0.113865821	4	0.536308603	18	0.472398125	18	0.475492387	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	Killer cell lectin-like receptor subfamily G member 2 GN=KLRG2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: killer cell lectin-like receptor subfamily G member 2 [Orcinus orca]
ENSG00000188895(MSL1)	--	33.009665	2232	35.02163983	2438	33.65816011	2354	30.37038	2037	31.648146	2149	30.93122	2193	0.978934241	-0.162606084	normal	0.973056973	-0.203324758	normal	0.984755909	-0.110426433	normal	0.409728009	-0.159918969	normal	--	--	--	K13163|0|ptr:454645|MSL1; male-specific lethal 1 homolog (Drosophila); K13163 male-specific lethal 1 (A)	--	--	--	PEHE domain	Male-specific lethal 1 homolog GN=MSL1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: male-specific lethal 1 homolog isoform X1 [Mustela putorius furo] 
ENSG00000188897(CTD-3088G3.8)	--	0.168958154	7	0.100544113	12	0.023610452	3	0.010218982	2	0.024921494	1	0.145699868	22	--	--	--	--	--	--	0.119769092	2.374849005	normal	--	--	--	--	--	Molecular Function: lipid transporter activity (GO:0005319);; Biological Process: lipid transport (GO:0006869);; 	--	--	--	--	Lipoprotein amino terminal region;; Domain of unknown function (DUF1943);; von Willebrand factor type D domain;; C8 domain	Putative uncharacterized protein LOC400499 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC100340141 [Oryctolagus cuniculus]
ENSG00000188906(LRRK2)	--	2.9618796	485	3.251847138	513	2.573300513	415	3.21130791	517	3.28845278	539	3.4978731	565	0.970060594	0.061159605	normal	0.970485629	0.049756788	normal	0.632713812	0.435482867	normal	0.482780582	0.176876018	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: GTP binding (GO:0005525);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K08844|0|hsa:120892|LRRK2, AURA17, DARDARIN, PARK8, RIPK7, ROCO2; leucine-rich repeat kinase 2 (EC:2.7.11.1); K08844 leucine-rich repeat kinase 2 [EC:2.7.11.1] (A)"	Parkinson's disease (ko05012)	--	--	Protein kinase domain;; Protein tyrosine kinase;; Miro-like protein;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Ras family;; Leucine Rich Repeat;; Leucine Rich repeat;; ADP-ribosylation factor family;; Leucine rich repeat	Leucine-rich repeat serine/threonine-protein kinase 2 GN=LRRK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat serine/threonine-protein kinase 2-like [Odobenus rosmarus divergens]
ENSG00000188910(GJB3)	--	0.254045324	10	0.2071289	8	0.242003678	9	1.131023863	45	1.226757272	48	0.3338746	13	0.004139414	1.983890195	up	0.000154489	2.360526878	up	--	--	--	--	--	--	--	--	--	"K07622|3.90849e-148|pps:100990117|GJB3; gap junction protein, beta 3, 31kDa; K07622 gap junction protein, beta 3 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction beta-3 protein GN=GJB3 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gap junction beta-3 protein [Ursus maritimus]
ENSG00000188916(FAM196A)	--	2.56693007	181	2.372249	160	2.868629	174	0.667007482	41	0.3768408	19	0.4437916	29	9.28E-13	-2.131558037	down	0	-2.997620097	down	7.77E-16	-2.532160006	down	3.93E-15	-2.555322746	down	--	--	--	--	--	--	--	FAM196 family	Protein FAM196A GN=FAM196A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM196A isoform X1 [Tupaia chinensis]
ENSG00000188917(TRMT2B)	--	9.572153989	650	10.23298022	673	11.373578	748	9.482526619	633	8.88024299	584	11.101982	699	0.972319771	-0.068901433	normal	0.941133609	-0.225520145	normal	0.970844024	-0.1058159	normal	0.586683317	-0.13294546	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: RNA processing (GO:0006396);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: RNA methyltransferase activity (GO:0008173);; 	"K15331|0|hsa:79979|TRMT2B, CXorf34, dJ341D10.3; tRNA methyltransferase 2 homolog B (S. cerevisiae) (EC:2.1.1.35); K15331 tRNA (uracil-5-)-methyltransferase [EC:2.1.1.35] (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Methyltransferase domain;; tRNA (Uracil-5-)-methyltransferase;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase small domain	tRNA (uracil(54)-C(5))-methyltransferase homolog GN=TRMT2B OS=Homo sapiens (Human) PE=2 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA (uracil(54)-C(5))-methyltransferase homolog [Ceratotherium simum simum]
ENSG00000188921(HACD4)	--	1.286007835	146	0.941651194	104	1.194604507	129	1.691489616	192	1.683369337	190	1.068704856	120	0.883065496	0.360984472	normal	0.038535529	0.838837517	normal	0.965468299	-0.11127524	normal	0.33299328	0.38321728	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Protein tyrosine phosphatase-like protein, PTPLA"	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 4 GN=PTPLAD2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 4 [Lipotes vexillifer]
ENSG00000188931(CFAP126)	--	0.403196	4	1.41959	14	1.48534	14	1.44863	15	2.14189	21	1.25714	13	--	--	--	0.981489886	0.517638856	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein Flattop {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0740 protein C1orf192 homolog [Ceratotherium simum simum]
ENSG00000188938(FAM120AOS)	--	20.958529	694	20.14738803	652	21.838502	723	25.910067	860	21.877495	721	24.810291	822	0.914711208	0.278014984	normal	0.967460772	0.123428417	normal	0.960262472	0.176504843	normal	0.360022697	0.194641433	normal	--	--	--	--	--	--	--	--	Putative FAM120A opposite strand protein GN=FAM120AOS OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	"PREDICTED: constitutive coactivator of PPAR-gamma-like protein 1-like, partial [Leptonychotes weddellii]"
ENSG00000188958(UTS2B)	--	0.0258945	1	0	0	0	0	0.060264932	2	0	0	0.025534509	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: hormone activity (GO:0005179);; Cellular Component: extracellular region (GO:0005576);; Biological Process: regulation of blood pressure (GO:0008217);; 	--	--	--	--	Urotensin II	Urotensin-2B (Precursor) GN=UTS2B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: urotensin-2B [Leptonychotes weddellii]
ENSG00000188959(C9orf152)	--	0.0912602	4	0.0461086	2	0.0227833	0	0.0229799	1	0.0222083	0	0.0225628	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf152 GN=C9orf152 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C9orf152 homolog [Galeopterus variegatus]
ENSG00000188976(NOC2L)	--	31.462801	1856	28.811667	1761	33.2362	2033	30.73041	1824	30.01112	1759	24.86342	1469	0.985224597	-0.055876583	normal	0.985153604	-0.023046182	normal	0.447327605	-0.476648251	normal	0.332467214	-0.182967873	normal	--	--	--	"K14833|0|hsa:26155|NOC2L, NET15, NET7, NIR, PPP1R112; nucleolar complex associated 2 homolog (S. cerevisiae); K14833 nucleolar complex protein 2 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Noc2p family	Nucleolar complex protein 2 homolog GN=NOC2L OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: nucleolar complex protein 2 homolog [Tupaia chinensis]
ENSG00000188981(MSANTD1)	--	0.34941004	15	0.158149747	7	0.154521459	7	0.068686361	3	0.050052555	1	0.085688358	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Myb/SANT-like DNA-binding domain	Myb/SANT-like DNA-binding domain-containing protein 1 GN=MSANTD1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: myb/SANT-like DNA-binding domain-containing protein 1 [Tupaia chinensis]
ENSG00000188986(NELFB)	--	36.849922	1714	32.87549	1560	34.623416	1718	32.93728	1605	37.044183	1764	33.537236	1633	0.979813168	-0.125509777	normal	0.975998078	0.155735934	normal	0.983186827	-0.081423163	normal	0.955665903	-0.018096311	normal	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	"K15180|0|ptr:736409|NELFB, COBRA1; negative elongation factor complex member B; K15180 negative elongation factor B (A)"	--	--	--	Cofactor of BRCA1 (COBRA1)	Negative elongation factor B GN=NELFB OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: negative elongation factor B [Bos taurus]
ENSG00000188992(LIPI)	--	0	0	0	0	0	0	0.09230881	2	0.045488726	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Lipase	Lipase member I (Precursor) GN=LIPI OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: lipase member I isoform X2 [Tupaia chinensis]
ENSG00000188993(LRRC66)	--	0.161479	11	0.0588564	4	0.218299	14	0.191364	13	0.071375	4	0.189383	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich repeat;; Leucine Rich Repeat	Leucine-rich repeat-containing protein 66 GN=LRRC66 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: leucine-rich repeat-containing protein 66 [Ceratotherium simum simum]
ENSG00000188994(ZNF292)	--	9.706524716	691	5.591590864	1028	4.979235469	918	5.907098647	688	5.836944137	605	9.200809358	855	0.974646396	-0.037026901	normal	0.001178198	-0.784736377	normal	0.972995101	-0.110672214	normal	0.364872585	-0.316452698	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 292 GN=ZNF292 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 292 [Canis lupus familiaris]
ENSG00000188996(HUS1B)	--	0.33453	5	0.0638832	1	0.0629118	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: DNA damage checkpoint (GO:0000077);; Cellular Component: checkpoint clamp complex (GO:0030896);; 	K10996|2.94852e-175|hsa:135458|HUS1B; HUS1 checkpoint homolog b (S. pombe); K10996 checkpoint protein HUS1B (A)	--	[DL]	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	Hus1-like protein	Checkpoint protein HUS1B GN=HUS1B OS=Homo sapiens (Human) PE=1 SV=2	DL	"Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	PREDICTED: checkpoint protein HUS1B [Ochotona princeps]
ENSG00000188997(KCTD21)	--	4.639548873	269	4.03655	207	2.956846	199	3.46593	230	3.471465004	228	3.593112001	234	0.928221924	-0.255226044	normal	0.960126566	0.117160721	normal	0.941729513	0.223878129	normal	0.983948554	0.01449198	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD21 GN=KCTD21 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	BTB/POZ domain-containing protein KCTD21 [Pteropus alecto]
ENSG00000189001(SBSN)	--	0.672751	12	0.496907	15	0.1773529	4	0.927422658	26	0.684307	14	0.330154384	11	0.91932654	0.99626999	normal	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	--	--	--	Suprabasin (Precursor) GN=SBSN OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: suprabasin [Myotis lucifugus]
ENSG00000189007(ADAT2)	--	3.488738	173	3.417058	170	3.630498761	183	4.157338131	214	4.048255	184	2.835164235	143	0.926590049	0.273816799	normal	0.96291231	0.091958045	normal	0.885889722	-0.360738806	normal	0.979034145	0.018313884	normal	[FJ]	"Nucleotide transport and metabolism;; Translation, ribosomal structure and biogenesis"	Biological Process: tRNA wobble adenosine to inosine editing (GO:0002100);; Molecular Function: tRNA-specific adenosine deaminase activity (GO:0008251);; 	"K15441|4.57786e-131|mcf:102135928|ADAT2; adenosine deaminase, tRNA-specific 2; K15441 tRNA-specific adenosine deaminase 2 [EC:3.5.4.-] (A)"	--	[F]	Nucleotide transport and metabolism	Cytidine and deoxycytidylate deaminase zinc-binding region	tRNA-specific adenosine deaminase 2 GN=ADAT2 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	PREDICTED: tRNA-specific adenosine deaminase 2 [Galeopterus variegatus]
ENSG00000189030(VHLL)	--	0.128953	1	0	0	0.122453	0	0.123561	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	von Hippel-Lindau disease tumour suppressor protein	Von Hippel-Lindau-like protein GN=VHLL OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: von Hippel-Lindau disease tumor suppressor [Equus przewalskii]
ENSG00000189042(ZNF567)	--	5.079557881	264	6.5900231	335	5.533291	284	5.378529179	284	5.698233725	293	5.522624025	291	0.965067919	0.074104888	normal	0.940727059	-0.213654759	normal	0.967382926	0.026696343	normal	0.912045375	-0.045964447	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:163081|ZNF567; zinc finger protein 567; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; GATA zinc finger;; CpXC protein;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 567 GN=ZNF567 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 567 [Galeopterus variegatus] 
ENSG00000189043(NDUFA4)	--	59.79340363	1685	65.5666493	1836	59.14690114	1629	61.285012	1747	56.4903426	1595	67.31685678	1903	0.985282849	0.021279698	normal	0.961998793	-0.224237833	normal	0.965081832	0.215811977	normal	0.988833633	0.005237379	normal	--	--	--	"K03948|4.80764e-54|ptr:741211|NDUFA4; NDUFA4, mitochondrial complex associated; K03948 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 4 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	--	--	NADH-ubiquinone reductase complex 1 MLRQ subunit	Cytochrome c oxidase subunit NDUFA4 GN=NDUFA4 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like [Dasypus novemcinctus]
ENSG00000189045(ANKDD1B)	--	0.0211193	1	0	0	0.0206316	0	0	0	0	0	0.3565731	12	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Death domain	Ankyrin repeat and death domain-containing protein 1B GN=ANKDD1B OS=Homo sapiens (Human) PE=3 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: ankyrin repeat and death domain-containing protein 1B [Pteropus alecto]
ENSG00000189046(ALKBH2)	--	21.88930008	359	19.76486194	342	21.64383009	364	21.89634564	356	24.22119929	399	18.8768851	309	0.968036098	-0.042755114	normal	0.945114904	0.200145855	normal	0.930146227	-0.243523645	normal	0.962333677	-0.02277337	normal	[L]	"Replication, recombination and repair"	--	"K10859|0|ptr:452216|ALKBH2; alkB, alkylation repair homolog 2 (E. coli); K10859 alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 [EC:1.14.11.-] (A)"	--	--	--	2OG-Fe(II) oxygenase superfamily	Alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 GN=ALKBH2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: alpha-ketoglutarate-dependent dioxygenase alkB homolog 2 [Galeopterus variegatus] 
ENSG00000189050(RNFT1)	--	16.32553522	406	16.774613	410	15.293463	428	13.8302243	375	12.415998	355	13.0752708	379	0.958799769	-0.144850802	normal	0.935521842	-0.228325451	normal	0.951162556	-0.183016731	normal	0.496045113	-0.186823952	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[S]	Function unknown	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger and transmembrane domain-containing protein 1 GN=RNFT1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: RING finger and transmembrane domain-containing protein 1 [Canis lupus familiaris]
ENSG00000189051(RNF222)	--	0.070168179	4	0.034324398	2	0.033661548	1	0.105000248	6	0.068326013	3	0.121429844	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	"Ring finger domain;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; RING-type zinc-finger;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 222 GN=RNF222 OS=Homo sapiens (Human) PE=3 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 222 [Condylura cristata]
ENSG00000189052(CGB5)	--	0	0	0	0	0	0	0.180329	2	0.0893744	0	0.270098	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10045|4.00276e-90|hsa:93659|CGB5, HCG; chorionic gonadotropin, beta polypeptide 5; K10045 chorionic gonadotropin, beta polypeptide (A)"	--	--	--	Cystine-knot domain	Choriogonadotropin subunit beta variant 2 (Precursor) GN=CGB2 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: lutropin subunit beta [Bos mutus]
ENSG00000189056(RELN)	--	0.00439008	1	0.00436918	1	0.00435514	0	0.039649366	9	0.00855271	1	0.02189834	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06249|0|hsa:5649|RELN, LIS2, PRO1598, RL; reelin; K06249 reelin [EC:3.4.21.-] (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512)	--	--	Reeler domain;; EGF-like domain;; BNR/Asp-box repeat;; EB module;; Human growth factor-like EGF	Reelin (Precursor) GN=RELN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: reelin isoform 1 [Ceratotherium simum simum]
ENSG00000189057(FAM111B)	--	9.03682493	620	10.20530567	674	11.61552379	772	12.17075341	825	10.12298608	689	6.229156795	428	0.76711965	0.380473927	normal	0.974475346	0.010305963	normal	0.000233434	-0.856993543	normal	0.841859389	-0.112000228	normal	--	--	--	--	--	--	--	"Trypsin-like peptidase domain;; Peptidase S7, Flavivirus NS3 serine protease"	Protein FAM111B GN=FAM111B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM111B [Galeopterus variegatus]
ENSG00000189058(APOD)	--	0.205343983	4	0.445567	7	0.399355	7	0.150636278	3	0.3875372	4	0.4319304	8	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Biological Process: evasion or tolerance of host defense response (GO:0030682);; 	K03098|1.60743e-120|hsa:347|APOD; apolipoprotein D; K03098 apolipoprotein D and lipocalin family protein (A)	--	[M]	Cell wall/membrane/envelope biogenesis	Lipocalin-like domain;; Lipocalin / cytosolic fatty-acid binding protein family;; Triabin	Apolipoprotein D (Precursor) GN=APOD OS=Homo sapiens (Human) PE=1 SV=1	M	Cell wall/membrane/envelope biogenesis	PREDICTED: apolipoprotein D isoform X1 [Bos taurus]
ENSG00000189060(H1F0)	--	92.9195	4298	54.4865	2548	69.768	3262	59.3254	2746	62.1065	2865	78.0005	3621	0.009706294	-0.676860633	normal	0.983417913	0.147660621	normal	0.986693822	0.142277322	normal	0.766535525	-0.151126454	normal	--	--	Cellular Component: nucleosome (GO:0000786);; Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K11275|5.32129e-54|cjc:100401444|H1F0; H1 histone family, member 0; K11275 histone H1/5 (A)"	--	[B]	Chromatin structure and dynamics	linker histone H1 and H5 family	"Histone H1.0, N-terminally processed GN=H1F0 OS=Homo sapiens (Human) PE=1 SV=3"	B	Chromatin structure and dynamics	PREDICTED: histone H1.0 [Galeopterus variegatus]
ENSG00000189067(LITAF)	--	171.6943709	5488	222.747819	7234	173.3521764	5426	116.8889268	3625	113.5642407	3499	146.3123136	4535	0.037527717	-0.628913394	normal	2.16E-08	-1.068948785	down	0.971375397	-0.266996425	normal	0.007635183	-0.659247311	normal	--	--	--	--	--	--	--	LITAF-like zinc ribbon domain	Lipopolysaccharide-induced tumor necrosis factor-alpha factor GN=LITAF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	lipopolysaccharide-induced tumor necrosis factor-alpha factor [Equus caballus] 
ENSG00000189068(VSTM1)	--	0	0	0.203756914	1	0.245109568	1	0.385981813	2	0.399789546	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin domain	V-set and transmembrane domain-containing protein 1 (Precursor) GN=VSTM1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: V-set and transmembrane domain-containing protein 1 isoform X3 [Equus caballus]
ENSG00000189077(TMEM120A)	--	25.765111	546	23.374927	479	25.261822	535	16.70044	349	19.224766	397	23.435643	495	0.030960927	-0.674111933	normal	0.89972173	-0.291301301	normal	0.965132711	-0.12004892	normal	0.096568757	-0.350075039	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	TMPIT-like protein	Transmembrane protein 120A GN=TMEM120A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 120A isoform X2 [Galeopterus variegatus]
ENSG00000189079(ARID2)	--	8.20229357	1122	8.893357578	1297	8.129201275	1118	7.15393927	1029	9.154454384	1276	7.042562077	1003	0.969628977	-0.155439591	normal	0.981317896	-0.044923897	normal	0.967853487	-0.164654752	normal	0.621092743	-0.117876279	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K11765|0|hsa:196528|ARID2, BAF200, p200; AT rich interactive domain 2 (ARID, RFX-like); K11765 AT-rich interactive domain-containing protein 2 (A)"	--	[K]	Transcription	ARID/BRIGHT DNA binding domain;; RFX DNA-binding domain	AT-rich interactive domain-containing protein 2 GN=ARID2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 2 [Ceratotherium simum simum]
ENSG00000189091(SF3B3)	--	30.46211339	5033	27.99906172	4925	29.85014785	5201	36.4567802	6553	34.67308386	6253	32.4563833	5964	0.929023673	0.349810857	normal	0.950554906	0.322910056	normal	0.987299027	0.189148381	normal	0.097955906	0.286864497	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: nucleus (GO:0005634);; 	"K12830|0|tup:102478444|SF3B3; splicing factor 3b, subunit 3, 130kDa; K12830 splicing factor 3B subunit 3 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	CPSF A subunit region;; Mono-functional DNA-alkylating methyl methanesulfonate N-term	Splicing factor 3B subunit 3 GN=SF3B3 OS=Homo sapiens (Human) PE=1 SV=4	A	RNA processing and modification	PREDICTED: splicing factor 3B subunit 3 isoform 1 [Canis lupus familiaris] 
ENSG00000189114(BLOC1S3)	--	11.328052	452	15.228031	602	10.144559	405	8.374821	332	10.691561	403	12.82052	521	0.53376118	-0.474083062	normal	0.117714991	-0.598559276	normal	0.827122019	0.353901982	normal	0.609310002	-0.236490771	normal	--	--	--	--	--	--	--	--	Biogenesis of lysosome-related organelles complex 1 subunit 3 GN=BLOC1S3 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: biogenesis of lysosome-related organelles complex 1 subunit 3 [Canis lupus familiaris]
ENSG00000189120(SP6)	--	0.912671895	64	0.716004169	52	0.951118885	69	2.028321053	144	1.195041881	83	0.676377856	48	0.002546954	1.120702664	up	0.774600802	0.63835881	normal	0.90851692	-0.518163976	normal	0.547384911	0.547807629	normal	[R]	General function prediction only	--	"K09196|0|hsa:80320|SP6, EPFN, EPIPROFIN, KLF14; Sp6 transcription factor; K09196 transcription factor Sp6 (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Transcription factor Sp6 GN=SP6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor Sp6 [Canis lupus familiaris]
ENSG00000189127(ANKRD34B)	--	0.1701391	11	0.078965473	5	0.1077447	6	0.062258657	4	0.120767526	7	0.046438152	3	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 34B GN=ANKRD34B OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 34B [Panthera tigris altaica]
ENSG00000189129(PLAC9)	--	0.400019	4	0.195116	2	0.094534432	0	0.38837	4	0.194218	1	0.0978804	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Placenta-specific protein 9	Placenta-specific protein 9 (Precursor) GN=PLAC9 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"Placenta-specific protein 9, partial [Bos mutus]"
ENSG00000189134(NKAPL)	--	0	0	0	0	0	0	0.0281869	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: chromatin binding (GO:0003682);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: negative regulation of transcription, DNA-templated (GO:0045892);; "	--	--	[S]	Function unknown	Ras-induced vulval development antagonist	NKAP-like protein GN=NKAPL OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	"PREDICTED: NKAP-like protein, partial [Ursus maritimus]"
ENSG00000189143(CLDN4)	--	2.238329	90	1.19712503	47	2.89551729	99	6.79818401	216	6.22983707	198	2.12445994	84	2.81E-05	1.21837403	up	4.31E-12	2.019044074	up	0.957128867	-0.241323982	normal	0.152656757	1.054695524	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K06087|1.61851e-108|ptr:463464|CLDN4; claudin 4; K06087 claudin (A)	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-4 GN=CLDN4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: claudin-4 [Lipotes vexillifer]
ENSG00000189144(ZNF573)	--	2.619100676	277	2.938407663	329	2.124757406	294	3.367848394	283	2.989393606	268	1.67860137	312	0.967502314	8.34E-05	normal	0.886175339	-0.315670282	normal	0.965320106	0.077053639	normal	0.830156026	-0.081582107	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; NTF2 fold immunity protein;; Transposase zinc-ribbon domain"	Zinc finger protein 573 GN=ZNF573 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: zinc finger protein 573-like [Odobenus rosmarus divergens]
ENSG00000189152(GRAPL)	--	0.3479258	5	0.254894653	3	0.495547753	5	0.249795792	4	1.153795226	16	0.253266907	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	SH3 domain;; SH2 domain;; Variant SH3 domain;; Variant SH3 domain	GRB2-related adapter protein-like GN=GRAPL OS=Homo sapiens (Human) PE=3 SV=3	T	Signal transduction mechanisms	PREDICTED: GRB2-related adapter protein isoform X2 [Camelus dromedarius]
ENSG00000189164(ZNF527)	--	3.02865898	185	2.744851654	166	3.282066	183	3.927004141	208	2.615918	156	3.651799	210	0.959485426	0.137151391	normal	0.962033674	-0.11002953	normal	0.951367203	0.188796759	normal	0.864496211	0.083018309	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:84503|ZNF527; zinc finger protein 527; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc ribbon domain"	Zinc finger protein 527 GN=ZNF527 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 527 isoform X1 [Galeopterus variegatus]
ENSG00000189167(ZAR1L)	--	0	0	0.167780777	3	0.054619187	0	0	0	0	0	0.056859949	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18762|0|hsa:646799|ZAR1L, Z3CXXC7, ZAR2; zygote arrest 1-like; K18762 zygote arrest protein 1 (A)"	--	--	--	Zinc-binding domain	ZAR1-like protein GN=ZAR1L OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: ZAR1-like protein [Tupaia chinensis] 
ENSG00000189171(S100A13)	--	67.86691348	478	55.74563	429	65.67102398	467	105.627926	693	77.51245	570	77.150562	542	0.360264292	0.503661135	normal	0.766325927	0.387369523	normal	0.946190981	0.20595924	normal	0.060276955	0.37170111	normal	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A13 GN=S100A13 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein S100-A13 [Galeopterus variegatus]
ENSG00000189180(ZNF33A)	--	5.209068	556	7.625511876	782	5.60714555	639	5.687997456	604	6.359513061	660	7.940212237	845	0.969697053	0.088397006	normal	0.922800844	-0.265569333	normal	0.734137118	0.394030514	normal	0.878802895	0.072909688	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7581|ZNF33A, KOX2, KOX31, KOX5, NF11A, ZNF11, ZNF11A, ZNF33, ZZAPK; zinc finger protein 33A; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; BolA-like protein;; TFIIH C1-like domain"	Zinc finger protein 33A GN=ZNF33A OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 33B-like [Ursus maritimus]
ENSG00000189184(PCDH18)	--	0.011540108	1	0.052905378	5	0.126527982	11	0.118215225	9	0.081686986	8	0.0114561	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K16499|0|ptr:461491|PCDH18; protocadherin 18; K16499 protocadherin delta 2 (A)	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin-18 (Precursor) GN=PCDH18 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protocadherin-18-like [Trichechus manatus latirostris]
ENSG00000189190(ZNF600)	--	0.173407012	13	0.111743535	8	0.153503904	10	0.220770062	16	0.193639881	14	0.3587271	27	--	--	--	--	--	--	0.753589693	1.300882305	normal	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; BolA-like protein;; Zinc-finger of C2H2 type;; Zinc ribbon domain"	Zinc finger protein 600 GN=ZNF600 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 160-like [Galeopterus variegatus]
ENSG00000189221(MAOA)	--	5.0636564	355	2.7919239	195	3.791936	265	2.5333588	178	4.0318091	281	1.835299	129	6.56E-05	-1.020406592	down	0.576818518	0.502407322	normal	0.000234949	-1.038236284	down	0.44738228	-0.492550924	normal	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; Molecular Function: FAD binding (GO:0071949);; 	"K00274|0|hsa:4128|MAOA, MAO-A; monoamine oxidase A (EC:1.4.3.4); K00274 monoamine oxidase [EC:1.4.3.4] (A)"	"Glycine, serine and threonine metabolism (ko00260);; Arginine and proline metabolism (ko00330);; Histidine metabolism (ko00340);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Tryptophan metabolism (ko00380);; Drug metabolism - cytochrome P450 (ko00982);; Serotonergic synapse (ko04726);; Dopaminergic synapse (ko04728);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Alcoholism (ko05034)"	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Flavin containing amine oxidoreductase;; NAD(P)-binding Rossmann-like domain;; FAD dependent oxidoreductase;; FAD binding domain;; Pyridine nucleotide-disulphide oxidoreductase;; HI0933-like protein;; FAD binding domain;; Thi4 family	Amine oxidase [flavin-containing] A GN=MAOA OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: uncharacterized protein LOC101673386 [Mustela putorius furo]
ENSG00000189227(C15orf61)	--	3.174272019	175	4.426562022	212	3.508543087	188	3.191137032	158	2.2952601	132	3.238676023	166	0.955397503	-0.176629616	normal	0.157948437	-0.698575899	normal	0.953007279	-0.186245399	normal	0.292501838	-0.355741983	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4528)	Uncharacterized protein C15orf61 (Precursor) GN=C15orf61 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C15orf61 homolog [Galeopterus variegatus]
ENSG00000189241(TSPYL1)	--	22.752	1251	24.8437	1394	24.6428	1370	28.5659	1589	27.5967	1514	25.6324	1412	0.89971108	0.313862377	normal	0.980127508	0.097606464	normal	0.98289024	0.035234441	normal	0.468404216	0.147827589	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	"K11284|0|hsa:7259|TSPYL1, TSPYL; TSPY-like 1; K11284 TSPY-like 1 (A)"	--	[L]	"Replication, recombination and repair"	Nucleosome assembly protein (NAP)	Testis-specific Y-encoded-like protein 1 GN=TSPYL1 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: testis-specific Y-encoded-like protein 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000189266(PNRC2)	--	19.41034923	715	18.53476416	696	18.8874359	695	27.14235771	1027	30.80816136	1142	24.98605092	904	0.376481128	0.490704724	normal	0.010750511	0.691792167	normal	0.79135668	0.370309896	normal	0.000935575	0.523655503	normal	--	--	--	K18751|6.18256e-84|hsa:55629|PNRC2; proline-rich nuclear receptor coactivator 2; K18751 proline-rich nuclear receptor coactivator 2 (A)	--	--	--	Proline-rich nuclear receptor coactivator	Proline-rich nuclear receptor coactivator 2 GN=PNRC2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	proline-rich nuclear receptor coactivator 2 [Sus scrofa]
ENSG00000189269(DRICH1)	--	0.37256442	9	0.243510234	6	0.280989367	6	0.163211094	4	0	0	0.609161	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Aspartate-rich protein 1 GN=DRICH1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000189280(GJB5)	--	0	0	0	0	0.0449619	0	0.0460798	1	0.0450863	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07624|0|hsa:2709|GJB5, CX31.1; gap junction protein, beta 5, 31.1kDa; K07624 gap junction protein, beta 5 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction beta-5 protein GN=GJB5 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: gap junction beta-5 protein [Orycteropus afer afer]
ENSG00000189283(FHIT)	--	24.10236615	41	13.5345694	36	18.81567517	28	13.11746761	44	28.28620759	48	55.06840658	57	0.980790231	0.068566853	normal	0.963822926	0.379755918	normal	0.50355117	0.979452001	normal	0.436464399	0.484006132	normal	[FGR]	Nucleotide transport and metabolism;; Carbohydrate transport and metabolism;; General function prediction only	--	"K01522|3.07441e-94|hsa:2272|FHIT, AP3Aase, FRA3B; fragile histidine triad (EC:3.6.1.29); K01522 bis(5'-adenosyl)-triphosphatase [EC:3.6.1.29] (A)"	Purine metabolism (ko00230);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[FR]	Nucleotide transport and metabolism;; General function prediction only	HIT domain;; Scavenger mRNA decapping enzyme C-term binding	Bis(5'-adenosyl)-triphosphatase GN=FHIT OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: bis(5'-adenosyl)-triphosphatase [Equus caballus] 
ENSG00000189292(ALKAL2)	--	0	0	0	0	0.051846919	0	0.098175981	1	0.051686967	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor signaling protein tyrosine kinase activator activity (GO:0030298);; Molecular Function: receptor tyrosine kinase binding (GO:0030971);; 	--	--	--	--	FAM150 family	Protein FAM150B (Precursor) GN=FAM150B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM150B [Equus caballus]
ENSG00000189298(ZKSCAN3)	--	1.190286997	87	1.37972	104	1.250903905	97	1.060203	82	0.863801569	70	1.246514313	103	0.970264229	-0.114146868	normal	0.75710279	-0.58219441	normal	0.969491418	0.077129168	normal	0.725447385	-0.196142322	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:80317|ZKSCAN3, ZF47, ZFP306, ZNF306, ZNF309, ZSCAN13, ZSCAN35, Zfp47, dJ874C20.1, dJ874C20.1., zfp-47; zinc finger with KRAB and SCAN domains 3; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box"	Zinc finger protein with KRAB and SCAN domains 3 GN=ZKSCAN3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein with KRAB and SCAN domains 4-like [Loxodonta africana]
ENSG00000189306(RRP7A)	--	20.22099	1798	18.3236	1719	20.24358	1839	21.80859	1982	21.65522	1968	18.2374	1700	0.982733822	0.109642422	normal	0.97489722	0.173591307	normal	0.981018508	-0.121574163	normal	0.826877892	0.055576303	normal	--	--	--	"K14545|1.03394e-179|hsa:27341|RRP7A, BK126B4.3, CGI-96; ribosomal RNA processing 7 homolog A (S. cerevisiae); K14545 ribosomal RNA-processing protein 7 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	"Ribosomal RNA-processing protein 7 (RRP7);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Ribosomal RNA-processing protein 7 homolog A GN=RRP7A OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ribosomal RNA-processing protein 7 homolog A [Ursus maritimus]
ENSG00000189308(LIN54)	--	4.116025246	310	5.459775616	415	5.7667008	389	5.046825302	384	4.726094549	352	6.1744483	450	0.911910937	0.276771469	normal	0.921824631	-0.257940525	normal	0.946295997	0.201135804	normal	0.845186733	0.069666795	normal	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	"Tesmin/TSO1-like CXC domain, cysteine-rich domain"	Protein lin-54 homolog GN=LIN54 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: protein lin-54 homolog isoform X3 [Canis lupus familiaris]
ENSG00000189319(FAM53B)	--	16.37734846	883	15.04380746	937	15.00599362	973	18.54955634	1051	16.39871028	1048	15.1916806	989	0.950938327	0.220093705	normal	0.970469448	0.13987766	normal	0.979310664	0.015215817	normal	0.583066321	0.123611026	normal	--	--	--	--	--	--	--	Family of FAM53	Protein FAM53B GN=FAM53B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	"PREDICTED: protein FAM53B, partial [Galeopterus variegatus]"
ENSG00000189334(S100A14)	--	0.118973326	2	0.165264046	3	0.436142553	7	0.231449929	4	0.175651216	2	0.117355089	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A14 GN=S100A14 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein S100-A14 [Vicugna pacos]
ENSG00000189337(KAZN)	--	2.727316179	210	2.273309243	168	2.087192161	166	1.071584907	80	1.527870782	111	0.841927082	64	6.05E-07	-1.405818729	down	0.474559953	-0.612494266	normal	1.51E-05	-1.362587799	down	0.000147712	-1.114819184	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Kazrin GN=KAZN OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: kazrin isoform X4 [Bos taurus]
ENSG00000189339(SLC35E2B)	--	14.17581869	1464	13.90536744	1443	13.82588498	1440	11.86602816	1224	12.14853422	1249	16.05975983	1670	0.921124186	-0.288812226	normal	0.954805846	-0.229465628	normal	0.965447999	0.205287484	normal	0.758175957	-0.089627328	normal	--	--	Biological Process: transmembrane transport (GO:0055085);; 	"K15284|0|hsa:728661|SLC35E2B, SLC35E2; solute carrier family 35, member E2B; K15284 solute carrier family 35, member E2 (A)"	--	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Triose-phosphate Transporter family;; EamA-like transporter family;; UAA transporter family	Solute carrier family 35 member E2B GN=SLC35E2B OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 35 member E2-like isoform X1 [Tupaia chinensis] 
ENSG00000189350(TOGARAM2)	--	0.010157551	2	0.019920359	4	0	0	0.02527325	6	0	0	0.015155456	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	CLASP N terminal	Protein FAM179A GN=FAM179A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM179A [Pantholops hodgsonii]
ENSG00000189362(NEMP2)	--	3.6582455	263	3.004565	223	4.461672	232	3.018715	202	2.95307606	182	2.869422	198	0.792054484	-0.408805651	normal	0.903751056	-0.312183848	normal	0.938339392	-0.235254034	normal	0.289261126	-0.324305616	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2215)	Transmembrane protein 194B GN=TMEM194B OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane protein 194B [Leptonychotes weddellii]
ENSG00000189366(ALG1L)	--	1.036484	10	0.828215	9	2.193734554	23	0.344352	3	0.47131633	4	0.85058	9	--	--	--	--	--	--	0.870332851	-1.228867774	normal	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyl transferases group 1	Putative glycosyltransferase ALG1-like GN=ALG1L OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: chitobiosyldiphosphodolichol beta-mannosyltransferase isoform X3 [Ursus maritimus]
ENSG00000189367(KIAA0408)	--	4.721211358	748	6.178480751	979	5.880490271	878	5.7686427	898	5.874084166	933	6.210120027	1006	0.942710225	0.232408762	normal	0.975268698	-0.090714774	normal	0.960738036	0.187743704	normal	0.674624401	0.102211176	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4482)	Uncharacterized protein KIAA0408 GN=KIAA0408 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA0408 homolog [Ceratotherium simum simum]
ENSG00000189369(GSPT2)	--	7.99309	424	7.70588	411	7.42614	391	7.17159	382	6.84499	362	6.59105	349	0.951575976	-0.180633856	normal	0.944197303	-0.203775676	normal	0.953425657	-0.17153038	normal	0.498998766	-0.187241081	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	"K03267|0|hsa:23708|GSPT2, ERF3B, GST2; G1 to S phase transition 2; K03267 peptide chain release factor subunit 3 (A)"	mRNA surveillance pathway (ko03015)	[J]	"Translation, ribosomal structure and biogenesis"	Elongation factor Tu GTP binding domain;; Elongation factor Tu C-terminal domain;; Elongation factor Tu domain 2;; Ataxin-2 C-terminal region	Eukaryotic peptide chain release factor GTP-binding subunit ERF3B GN=GSPT2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic peptide chain release factor GTP-binding subunit ERF3B [Galeopterus variegatus]
ENSG00000189377(CXCL17)	--	0.0570006	1	0.116318	2	0.056808	0	0.0571977	1	0.055423	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	VEGF co-regulated chemokine 1	VEGF coregulated chemokine 1 (Precursor) GN=CXCL17 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: VEGF coregulated chemokine 1 [Felis catus]
ENSG00000189403(HMGB1)	--	269.4722065	7430	276.6599768	7599	278.8042677	7441	312.7112043	8712	299.0094643	8106	242.4144811	6711	0.989772899	0.198771492	normal	0.994731381	0.071740215	normal	0.991624078	-0.15722654	normal	0.875438133	0.04447829	normal	--	--	--	--	--	[R]	General function prediction only	HMG-box domain;; HMG (high mobility group) box	High mobility group protein B1 GN=HMGB1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	unknown [Sus scrofa] 
ENSG00000189409(MMP23B)	--	0.176247008	3	0.233644525	3	0.213616696	3	0.222594395	4	0.21022429	3	0.33382652	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K08001|0|hsa:8510|MMP23B, MIFR, MIFR-1, MMP22, MMP23A; matrix metallopeptidase 23B; K08001 matrix metalloproteinase-23 (CA-MMP) [EC:3.4.24.-] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; ShK domain-like;; Immunoglobulin domain	"Matrix metalloproteinase-23, soluble form (Precursor) GN=MMP23B OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: matrix metalloproteinase-23 [Leptonychotes weddellii]
ENSG00000189410(SH2D5)	--	7.864332046	469	10.38870833	613	9.529527	599	5.713912	279	4.006473649	187	5.400706588	365	0.005305872	-0.776815689	normal	2.22E-16	-1.726097534	down	0.010590543	-0.720596094	normal	0.000212209	-1.036746688	down	--	--	--	--	--	--	--	Phosphotyrosine interaction domain (PTB/PID)	SH2 domain-containing protein 5 GN=SH2D5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: SH2 domain-containing protein 5 isoform X2 [Equus przewalskii]
ENSG00000189420(ZFP92)	--	0.742423289	91	0.728181941	89	1.123076666	134	0.732644295	88	0.686108587	82	0.667865898	83	0.97095123	-0.077858387	normal	0.967226084	-0.137178738	normal	0.411320585	-0.68936164	normal	0.484825392	-0.332257041	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100980886|ZFP92; ZFP92 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; CHY zinc finger"	Zinc finger protein 92 homolog GN=ZFP92 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 92 homolog [Camelus ferus]
ENSG00000189431(RASSF10)	--	4.14509	261	2.088458	112	2.843023	175	19.78032	1162	20.28224	1182	11.18942	637	0	2.117204951	up	0	3.360884139	up	0	1.846699656	up	6.07E-06	2.420948913	up	--	--	--	K09856|0|hsa:644943|RASSF10; Ras association (RalGDS/AF-6) domain family (N-terminal) member 10; K09856 Ras association domain-containing protein 9/10 (A)	--	[W]	Extracellular structures	--	Ras association domain-containing protein 10 GN=RASSF10 OS=Homo sapiens (Human) PE=2 SV=3	W	Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: ras association domain-containing protein 10 [Oryctolagus cuniculus]
ENSG00000189433(GJB4)	--	0.0163698	1	0.0327298	2	0	0	0.0497851	3	0.0160112	0	0.0325019	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K07623|0|hsa:127534|GJB4, CX30.3, EKV; gap junction protein, beta 4, 30.3kDa; K07623 gap junction protein, beta 4 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction beta-4 protein GN=GJB4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gap junction beta-4 protein isoform X1 [Mustela putorius furo] 
ENSG00000196072(BLOC1S2)	--	36.88950459	752	44.79837229	897	43.8407971	842	62.47465246	1262	57.43637765	1165	60.5585316	1225	0.004562379	0.71493597	normal	0.832997889	0.355196727	normal	0.216355946	0.531801799	normal	0.000491012	0.53065327	normal	--	--	--	"K16750|1.78048e-65|ptr:744662|BLOC1S2; biogenesis of lysosomal organelles complex-1, subunit 2; K16750 biogenesis of lysosome-related organelles complex 1 subunit 2 (A)"	--	[S]	Function unknown	Biogenesis of lysosome-related organelles complex-1 subunit 2	Biogenesis of lysosome-related organelles complex 1 subunit 2 GN=BLOC1S2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: biogenesis of lysosome-related organelles complex-1 subunit 2 isoform X1 [Equus caballus]
ENSG00000196074(SYCP2)	--	1.084095082	105	0.632728822	63	0.63026837	68	0.305241741	34	0.448348259	38	0.663409516	29	2.60E-05	-1.613918392	down	0.778688614	-0.728037992	normal	0.077826968	-1.195873436	normal	0.004526018	-1.246225789	down	--	--	--	--	--	--	--	--	Synaptonemal complex protein 2 GN=SYCP2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: synaptonemal complex protein 2 [Ceratotherium simum simum]
ENSG00000196081(ZNF724)	--	1.3776418	77	1.3717739	94	0.843335903	62	2.48277415	146	2.2557067	125	1.96025301	128	0.059793593	0.879266767	normal	0.903056517	0.384390386	normal	0.018339991	1.019837013	normal	0.033297231	0.753828402	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|ptr:455904|ZNF429, ZNF43; putative zinc finger protein 724; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; C1-like domain;; NTF2 fold immunity protein;; Transposase zinc-ribbon domain;; BolA-like protein"	Putative zinc finger protein 724 GN=ZNF724P OS=Homo sapiens (Human) PE=5 SV=3	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000196083(IL1RAP)	--	4.687897256	253	3.561035104	196	4.709026	218	6.091935466	339	5.097097865	321	3.728114092	236	0.796586416	0.389267264	normal	0.079386898	0.686117417	normal	0.96244073	0.105463968	normal	0.133468257	0.403630623	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K04723|0|mcf:102133222|IL1RAP; interleukin 1 receptor accessory protein; K04723 interleukin 1 receptor accessory protein (A)	Cytokine-cytokine receptor interaction (ko04060);; Apoptosis (ko04210);; Inflammatory mediator regulation of TRP channels (ko04750)	--	--	TIR domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin V-set domain	Interleukin-1 receptor accessory protein (Precursor) GN=IL1RAP OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor accessory protein isoform X1 [Oryctolagus cuniculus]
ENSG00000196092(PAX5)	--	0.005935564	1	0	0	0	0	0	0	0.005784822	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09383|0|ptr:747452|PAX5; paired box 5; K09383 paired box protein 5 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	'Paired box' domain;; Paired-box protein 2 C terminal	Paired box protein Pax-5 GN=PAX5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: paired box protein Pax-5 isoform X1 [Loxodonta africana]
ENSG00000196104(SPOCK3)	--	0.798245178	14	0.194825996	9	0.106796227	2	1.62860314	51	3.845141037	81	1.543865701	38	0.008755566	1.728803706	up	2.90E-10	2.9528438	up	5.59E-06	3.485471461	up	0.000340681	2.742056774	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	"K08136|0|ptr:461594|SPOCK3; sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3; K08136 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) (A)"	--	[R]	General function prediction only	Secreted protein acidic and rich in cysteine Ca binding region;; Thyroglobulin type-1 repeat;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Testican-3 (Precursor) GN=SPOCK3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: testican-3 isoform X1 [Equus przewalskii]
ENSG00000196109(ZNF676)	--	0	0	0	0	0	0	0.034487	2	0.0337364	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09228|0|hsa:163223|ZNF676; zinc finger protein 676; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; C1-like domain;; Domain of unknown function (DUF1610)"	Zinc finger protein 676 GN=ZNF676 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 184-like [Sarcophilus harrisii]
ENSG00000196110(ZNF699)	--	0.6436975	53	0.755281681	65	0.989419804	81	0.207761863	18	0.45152563	39	0.2778854	24	0.027606994	-1.510237056	normal	0.756016354	-0.736044403	normal	0.000145888	-1.701386408	down	0.00413491	-1.316393058	down	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:374879|ZNF699, hang; zinc finger protein 699; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain"	Zinc finger protein 699 GN=ZNF699 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 699 [Ceratotherium simum simum]
ENSG00000196116(TDRD7)	--	10.63884	677	7.510280038	586	9.61231	688	10.32425	650	9.3784	667	10.4617	647	0.971212945	-0.089341425	normal	0.959233047	0.164960305	normal	0.970738789	-0.096715034	normal	0.978502962	-0.011418495	normal	--	--	--	"K18405|0|hsa:23424|TDRD7, CATC4, PCTAIRE2BP, TRAP; tudor domain containing 7; K18405 tudor domain-containing protein 1/4/6/7 (A)"	--	[K]	Transcription	Tudor domain;; OST-HTH/LOTUS domain	Tudor domain-containing protein 7 GN=TDRD7 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: tudor domain-containing protein 7 isoform X1 [Ursus maritimus]
ENSG00000196118(CCDC189)	--	3.673956	35	3.2279323	42	1.45792661	32	1.709371137	21	2.860069295	33	2.051851	31	0.933834218	-0.726208688	normal	0.969905941	-0.354897553	normal	0.984122003	-0.051616627	normal	0.613812044	-0.379137627	normal	--	--	--	--	--	--	--	Flagellar C1a complex subunit C1a-32	Coiled-coil domain-containing protein C16orf93 GN=C16orf93 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein C16orf93 homolog isoform X1 [Felis catus]
ENSG00000196123(KIAA0895L)	--	3.09723134	187	3.728787864	247	3.277665794	213	2.9532764	187	2.496743154	156	3.197007079	209	0.96677873	-0.030581005	normal	0.143756437	-0.67911131	normal	0.966515929	-0.035388277	normal	0.472931219	-0.250121888	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF1704)	Uncharacterized protein KIAA0895-like GN=KIAA0895L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein KIAA0895-like homolog [Panthera tigris altaica]
ENSG00000196132(MYT1)	--	0.971932402	48	0.880447462	25	1.38562437	45	0.462661299	14	0.64216469	20	0.484017007	9	0.013693518	-1.701662009	normal	0.983056366	-0.321562599	normal	0.001095665	-2.153095508	down	0.008241201	-1.477824246	down	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; "	--	--	[K]	Transcription	"Myelin transcription factor 1;; Zinc finger, C2HC type"	Myelin transcription factor 1 GN=MYT1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: myelin transcription factor 1 isoform X2 [Galeopterus variegatus]
ENSG00000196136(SERPINA3)	--	0.203814244	6	0.033972415	1	0.166608001	4	0.561719243	17	2.37126279	71	0.637434863	19	--	--	--	1.52E-14	4.836410659	up	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K04525|0|hsa:12|SERPINA3, AACT, ACT, GIG25; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3; K04525 serpin peptidase inhibitor, clade A, member 3 (A)"	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Alpha-1-antichymotrypsin His-Pro-less (Precursor) GN=SERPINA3 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: LOW QUALITY PROTEIN: alpha-1-antichymotrypsin [Galeopterus variegatus]
ENSG00000196139(AKR1C3)	--	79.09709238	2087	82.31905916	2081	77.81339624	2100	316.7490007	8735	441.35352	11789	458.6631048	12364	0	2.033750895	up	0	2.479812085	up	0	2.548534261	up	1.81E-16	2.371381287	up	[R]	General function prediction only	--	"K04119|0|hsa:8644|AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS; aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357); K04119 aldo-keto reductase family 1 member C3 [EC:1.1.1.64 1.1.1.188 1.1.1.213] (A)"	Steroid hormone biosynthesis (ko00140);; Arachidonic acid metabolism (ko00590);; Ovarian steroidogenesis (ko04913)	[R]	General function prediction only	Aldo/keto reductase family	Aldo-keto reductase family 1 member C3 GN=AKR1C3 OS=Homo sapiens (Human) PE=1 SV=4	C	Energy production and conversion	PREDICTED: aldo-keto reductase family 1 member C1 homolog [Loxodonta africana]
ENSG00000196141(SPATS2L)	--	39.11277261	1785	43.21957195	1933	41.55155554	1994	33.14870559	1596	31.73164863	1408	29.03717907	1297	0.970120757	-0.192120677	normal	0.461993506	-0.478180526	normal	0.030828847	-0.628182968	normal	0.004150524	-0.431048599	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1387)	SPATS2-like protein GN=SPATS2L OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	"PREDICTED: spermatogenesis associated, serine-rich 2-like isoform X2 [Canis lupus familiaris]"
ENSG00000196150(ZNF250)	--	3.7144028	174	3.28668219	139	3.8503039	176	3.0283975	158	3.607982361	167	3.952017734	194	0.956677815	-0.168433397	normal	0.942104967	0.24094238	normal	0.960510683	0.131116331	normal	0.902498766	0.065584501	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pon:100432643|ZNF250; zinc finger protein 250; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 250 GN=ZNF250 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 250 isoform X1 [Tupaia chinensis] 
ENSG00000196151(WDSUB1)	--	9.360222214	263	10.55227011	294	9.898220325	277	4.382881458	121	3.804582046	105	6.379259945	178	2.67E-05	-1.140804815	down	3.02E-09	-1.493417857	down	0.175370613	-0.641892383	normal	8.91E-06	-1.065781319	down	[R]	General function prediction only	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: sequence-specific DNA binding (GO:0043565);; 	--	--	[R]	General function prediction only	"WD domain, G-beta repeat;; U-box domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Protein of unknown function (DUF3312);; Eukaryotic translation initiation factor eIF2A;; Sterile alpha motif (SAM)/Pointed domain"	"WD repeat, SAM and U-box domain-containing protein 1 GN=WDSUB1 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: WD repeat, SAM and U-box domain-containing protein 1 isoform X2 [Ursus maritimus]"
ENSG00000196152(ZNF79)	--	3.340612513	193	4.947976926	288	3.678349932	228	2.444998252	153	2.857980928	170	4.637618655	290	0.879315503	-0.36265052	normal	0.023857565	-0.776588771	normal	0.874161442	0.336742682	normal	0.721808438	-0.229340207	normal	[R]	General function prediction only	--	K09228|0|ggo:101137765|ZNF79; zinc finger protein 79 isoform 1; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; C1-like domain"	Zinc finger protein 79 GN=ZNF79 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 79 isoform X1 [Physeter catodon]
ENSG00000196154(S100A4)	--	847.1895856	4847	957.5435769	5548	810.2817852	4736	992.7708069	6046	864.5213142	4905	980.5814048	5760	0.966117263	0.287974766	normal	0.98545601	-0.199083451	normal	0.970224092	0.274028826	normal	0.579285972	0.12166718	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A4 GN=S100A4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein S100-A4 isoform X1 [Physeter catodon]
ENSG00000196155(PLEKHG4)	--	11.600908	689	12.3604446	658	10.490287	690	11.35495359	602	11.0211239	672	11.91499605	573	0.941796421	-0.225035375	normal	0.974198821	0.00892679	normal	0.913429534	-0.2756886	normal	0.491377359	-0.16246923	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Puratrophin-1 GN=PLEKHG4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: puratrophin-1 [Equus caballus]
ENSG00000196159(FAT4)	--	1.608920074	321	1.355366428	346	1.877638238	327	1.686864001	367	1.412452141	335	1.3727612	351	0.955027728	0.161650532	normal	0.965586243	-0.067736597	normal	0.964578626	0.09347164	normal	0.873103123	0.061778843	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16669|0|hsa:79633|FAT4, CDHF14, CDHR11, FAT-J, FATJ, HKLLS2, NBLA00548, VMLDS2; FAT atypical cadherin 4; K16669 protocadherin Fat 4 (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like;; Laminin G domain;; Laminin G domain;; EGF-like domain;; Calcium-binding EGF domain;; Cadherin prodomain like	Protocadherin Fat 4 (Precursor) GN=FAT4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protocadherin Fat 4 [Ceratotherium simum simum]
ENSG00000196172(ZNF681)	--	0.061769229	6	0.097211813	9	0.010812579	0	0.324951213	8	0.059627934	5	0.061195282	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; Domain of unknown function (DUF1610)"	Zinc finger protein 681 GN=ZNF681 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 850-like [Galeopterus variegatus]
ENSG00000196177(ACADSB)	--	8.200047125	681	8.597553073	701	7.14082483	618	6.773798069	668	8.205393306	661	6.953522265	589	0.973501512	-0.058505678	normal	0.969417011	-0.105955288	normal	0.971146629	-0.077436522	normal	0.771785816	-0.082136396	normal	[I]	Lipid transport and metabolism	"Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; Molecular Function: flavin adenine dinucleotide binding (GO:0050660);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K09478|0|hsa:36|ACADSB, 2-MEBCAD, ACAD7, SBCAD; acyl-CoA dehydrogenase, short/branched chain (EC:1.3.8.5); K09478 short/branched chain acyl-CoA dehydrogenase [EC:1.3.99.12] (A)"	"Fatty acid degradation (ko00071);; Valine, leucine and isoleucine degradation (ko00280);; Fatty acid metabolism (ko01212)"	[I]	Lipid transport and metabolism	"Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, N-terminal domain;; Acyl-CoA dehydrogenase, C-terminal domain;; Acyl-CoA dehydrogenase, middle domain"	"Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial (Precursor) GN=ACADSB OS=Homo sapiens (Human) PE=1 SV=1"	I	Lipid transport and metabolism	"PREDICTED: short/branched chain specific acyl-CoA dehydrogenase, mitochondrial isoform X2 [Tupaia chinensis]"
ENSG00000196182(STK40)	--	3.68786774	257	3.582899844	254	4.112146124	290	4.011626	288	3.769207103	261	4.224171311	296	0.959284647	0.132718426	normal	0.966062895	0.017690847	normal	0.967579719	0.021143696	normal	0.895762911	0.056230156	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16312|0|hsa:83931|STK40, SHIK, SgK495; serine/threonine kinase 40 (EC:2.7.11.1); K16312 serine/threonine-protein kinase 40 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase 40 GN=STK40 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 40 isoform X5 [Leptonychotes weddellii]
ENSG00000196187(TMEM63A)	--	4.430387835	319	4.264236	297	4.438780054	348	5.554140469	404	4.919571	380	5.964915184	443	0.887218337	0.308643177	normal	0.86613792	0.332609385	normal	0.8534513	0.338620723	normal	0.171024816	0.327321196	normal	--	--	Cellular Component: membrane (GO:0016020);; 	--	--	[R]	General function prediction only	"Domain of unknown function DUF221;; Late exocytosis, associated with Golgi transport;; Domain of unknown function (DUF4463);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	CSC1-like protein 1 GN=TMEM63A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane protein 63A [Pteropus alecto]
ENSG00000196188(CTSE)	--	0	0	0.24712244	10	0.268167016	10	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Biological Process: proteolysis (GO:0006508);; 	"K01382|0|hsa:1510|CTSE, CATE; cathepsin E (EC:3.4.23.34); K01382 cathepsin E [EC:3.4.23.34] (A)"	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal;; A1 Propeptide	Cathepsin E form II (Precursor) GN=CTSE OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin E [Ceratotherium simum simum]
ENSG00000196189(SEMA4A)	--	0.052125913	3	0.034341528	2	0.077350869	2	0.23277131	11	0.224781464	12	0.068874979	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06521|0|hsa:64218|SEMA4A, CORD10, RP35, SEMAB, SEMB; sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A; K06521 semaphorin 4 (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Sema domain;; Plexin repeat	Semaphorin-4A (Precursor) GN=SEMA4A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: semaphorin-4A isoform X2 [Equus przewalskii]
ENSG00000196196(HRCT1)	--	0.0622129	1	0.0613154	1	0.17929	2	0.124866	2	0.122449	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Histidine-rich carboxyl terminus protein 1 GN=HRCT1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: histidine-rich carboxyl terminus protein 1 [Pteropus alecto] 
ENSG00000196199(MPHOSPH8)	--	7.567333	772	7.752722989	735	9.2749663	885	9.515366	799	8.293241	857	9.681280903	870	0.976587104	0.01872576	normal	0.954104827	0.199743499	normal	0.977685499	-0.032896799	normal	0.839424806	0.058028529	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Chromo (CHRromatin Organisation MOdifier) domain;; Ankyrin repeat	M-phase phosphoprotein 8 GN=MPHOSPH8 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: M-phase phosphoprotein 8 [Oryctolagus cuniculus]
ENSG00000196208(GREB1)	--	0.946004426	84	1.20722398	125	1.14862899	81	0.982353188	106	1.652030607	118	2.187303905	222	0.945398912	0.299879321	normal	0.964852212	-0.103281493	normal	2.52E-07	1.429485843	up	0.429619118	0.601510669	normal	--	--	--	--	--	--	--	--	Protein GREB1 GN=GREB1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein GREB1 isoform 2 [Ceratotherium simum simum]
ENSG00000196209(SIRPB2)	--	0	0	0	0	0	0	0	0	0.020808424	0	0.021138824	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16826|0|hsa:284759|SIRPB2, PTPN1L, PTPNS1L3, dJ776F14.2; signal-regulatory protein beta 2; K16826 signal-regulatory protein beta 2 (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	Signal-regulatory protein beta-2 (Precursor) GN=SIRPB2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: signal-regulatory protein beta 2 [Camelus ferus]
ENSG00000196214(ZNF766)	--	7.548986735	515	6.639410716	437	7.920383909	539	6.410235839	394	4.915236659	321	6.217208893	441	0.695821258	-0.415786009	normal	0.583242388	-0.464602516	normal	0.894638716	-0.296875574	normal	0.064544468	-0.387815585	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:90321|ZNF766; zinc finger protein 766; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 766 GN=ZNF766 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 160-like isoform X3 [Galeopterus variegatus]
ENSG00000196218(RYR1)	--	0.40138464	31	1.049441346	32	0.280776356	28	1.14244677	67	1.057850091	85	0.970214246	69	0.257741189	1.045055365	normal	0.005302389	1.347459046	up	0.04859091	1.248568826	normal	0.004585387	1.258907749	up	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: ryanodine-sensitive calcium-release channel activity (GO:0005219);; Molecular Function: calcium channel activity (GO:0005262);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: cellular calcium ion homeostasis (GO:0006874);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04961|0|hsa:6261|RYR1, CCO, MHS, MHS1, PPP1R137, RYDR, RYR, RYR-1, SKRR; ryanodine receptor 1 (skeletal); K04961 ryanodine receptor 1 (A)"	Calcium signaling pathway (ko04020);; Circadian entrainment (ko04713);; Long-term depression (ko04730);; Oxytocin signaling pathway (ko04921)	[T]	Signal transduction mechanisms	"RIH domain;; RyR domain;; Ryanodine Receptor TM 4-6;; SPRY domain;; Inositol 1,4,5-trisphosphate/ryanodine receptor;; MIR domain;; RyR and IP3R Homology associated;; Ion transport protein;; EF-hand domain pair"	Ryanodine receptor 1 GN=RYR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: ryanodine receptor 1 [Tupaia chinensis]
ENSG00000196220(SRGAP3)	--	0.328085716	59	0.29804559	55	0.263079209	44	0.149553867	26	0.228852701	40	0.204813589	38	0.177921517	-1.16604169	normal	0.943249045	-0.46577575	normal	0.97742504	-0.211949741	normal	0.268823303	-0.623779275	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K07526|0|pps:100988208|SRGAP3; SLIT-ROBO Rho GTPase activating protein 3; K07526 SLIT-ROBO Rho GTPase activating protein (A)	Axon guidance (ko04360)	[Z]	Cytoskeleton	"RhoGAP domain;; Fes/CIP4, and EFC/F-BAR homology domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain"	SLIT-ROBO Rho GTPase-activating protein 3 GN=SRGAP3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SLIT-ROBO Rho GTPase-activating protein 3 isoform X2 [Galeopterus variegatus]
ENSG00000196227(FAM217B)	--	5.336965004	352	5.468163279	426	4.27216867	328	4.23274101	336	4.336675578	344	4.463682433	353	0.964183156	-0.097510751	normal	0.866556986	-0.328570637	normal	0.964253215	0.097248637	normal	0.71101323	-0.119883778	normal	--	--	--	--	--	--	--	FAM217 family	Protein FAM217B GN=FAM217B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM217B isoform X1 [Galeopterus variegatus] 
ENSG00000196230(TUBB)	--	526.0271711	25208	496.4691772	23809	569.2508624	27250	645.4395632	30889	573.509761	27336	437.3359532	21019	0.993186732	0.262364777	normal	0.996554614	0.177858018	normal	0.960010208	-0.382829377	normal	0.929003287	0.033146629	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	K07375|0|xma:102222694|uncharacterized LOC102222694; K07375 tubulin beta (A)	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta chain GN=TUBB OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tubulin beta chain-like [Tursiops truncatus]
ENSG00000196233(LCOR)	--	6.61788412	1171	7.329627524	1257	7.07065907	1254	7.931272036	1484	7.826292205	1457	8.60506111	1560	0.900637035	0.310555106	normal	0.966155706	0.191375661	normal	0.907443319	0.30638534	normal	0.117993633	0.268748199	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4553)	Uncharacterized protein C10orf12 GN=C10orf12 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C10orf12-like isoform X2 [Balaenoptera acutorostrata scammoni] 
ENSG00000196235(SUPT5H)	--	59.67073844	5163	57.6464568	5269	55.661709	5227	74.65482951	6598	81.58774119	6826	67.93922079	6172	0.95080634	0.322901739	normal	0.931903578	0.351995697	normal	0.981961622	0.231401783	normal	0.077955482	0.302216372	normal	[K]	Transcription	--	"K15172|0|hsa:6829|SUPT5H, SPT5, SPT5H, Tat-CT1; suppressor of Ty 5 homolog (S. cerevisiae); K15172 transcription elongation factor SPT5 (A)"	--	[K]	Transcription	"Early transcription elongation factor of RNA pol II, NGN section;; KOW motif;; Spt5 transcription elongation factor, acidic N-terminal;; Spt5 C-terminal nonapeptide repeat binding Spt4;; Protein of unknown function (DUF3912)"	Transcription elongation factor SPT5 GN=SUPT5H OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription elongation factor SPT5 isoform 1 [Ovis aries]
ENSG00000196236(XPNPEP3)	--	2.866177	405	48.013227	420	3.0564738	424	20.073306	504	24.538161	446	66.661555	483	0.905131902	0.283703237	normal	0.967696593	0.065000689	normal	0.953005197	0.179068692	normal	0.503126917	0.176938599	normal	[E]	Amino acid transport and metabolism	Molecular Function: aminopeptidase activity (GO:0004177);; Molecular Function: manganese ion binding (GO:0030145);; 	"K01262|0|pon:100174489|XPNPEP3; X-prolyl aminopeptidase (aminopeptidase P) 3, putative (EC:3.4.11.9); K01262 Xaa-Pro aminopeptidase [EC:3.4.11.9] (A)"	--	[E]	Amino acid transport and metabolism	"Metallopeptidase family M24;; Aminopeptidase P, N-terminal domain"	Probable Xaa-Pro aminopeptidase 3 GN=XPNPEP3 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: probable Xaa-Pro aminopeptidase 3 [Galeopterus variegatus]
ENSG00000196247(ZNF107)	--	2.554555072	412	2.781450752	454	3.8725307	466	2.993571219	476	2.687375066	367	2.868589538	499	0.953178703	0.176870958	normal	0.866755699	-0.327124272	normal	0.967707633	0.090135698	normal	0.984925516	-0.010257783	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|nle:100602371|ZNF107; zinc finger protein 107; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; SprT-like family;; C1-like domain;; BolA-like protein"	Zinc finger protein 107 GN=ZNF107 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000196262(PPIA)	--	1928.63859	20118	2049.54173	20987	2143.95489	21110	2372.110172	24284	1863.76723	20127	2405.0964	23744	0.993429142	0.240670177	normal	0.997538024	-0.081784344	normal	0.996661408	0.161334073	normal	0.678111511	0.110254001	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	K03767|5.08549e-118|pps:100973085|PPIA; peptidylprolyl isomerase A (cyclophilin A); K03767 peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	"Peptidyl-prolyl cis-trans isomerase A, N-terminally processed GN=PPIA OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase A [Loxodonta africana]
ENSG00000196263(ZNF471)	--	0.026169191	3	0.078340706	9	0.052068881	5	0.081298377	10	0.055429821	6	0.121479554	15	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:57573|ZNF471, ERP1, Z1971; zinc finger protein 471; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 471 GN=ZNF471 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 471 [Equus przewalskii] 
ENSG00000196267(ZNF836)	--	0.54561059	12	0.981619209	19	0.867637271	11	0.920848528	18	0.793767708	23	0.891481082	20	--	--	--	0.985883888	0.237040991	normal	0.972604746	0.774316443	normal	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:162962|ZNF836; zinc finger protein 836; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; GAGA factor;; BolA-like protein;; Zinc-finger of C2H2 type"	Zinc finger protein 836 GN=ZNF836 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 841 [Galeopterus variegatus]
ENSG00000196268(ZNF493)	--	0.336245831	9	0.442293127	15	0.260969463	12	0.886087216	18	0.700074861	21	0.742792241	29	--	--	--	0.983931825	0.427447027	normal	0.803733772	1.167496426	normal	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; SprT-like family"	Zinc finger protein 493 GN=ZNF493 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000196275(GTF2IRD2)	--	1.071261211	47	0.668912098	49	1.522383444	49	1.00756885	39	1.211731264	49	1.45851706	50	0.97288576	-0.289608664	normal	0.977923015	-0.020785079	normal	0.978893562	0.020236615	normal	0.92119102	-0.091761713	normal	--	--	--	--	--	--	--	GTF2I-like repeat	General transcription factor II-I repeat domain-containing protein 2A GN=GTF2IRD2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: general transcription factor II-I repeat domain-containing protein 2-like [Lipotes vexillifer]
ENSG00000196277(GRM7)	--	0	0	0	0	0	0	0	0	0	0	0.116296984	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04608|0|ggo:101123810|GRM7; metabotropic glutamate receptor 7 isoform 1; K04608 metabotropic glutamate receptor 6/7/8 (A)	Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Nine Cysteines Domain of family 3 GPCR;; Periplasmic binding protein	Metabotropic glutamate receptor 7 (Precursor) GN=GRM7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: metabotropic glutamate receptor 7 isoform X1 [Orycteropus afer afer]
ENSG00000196284(SUPT3H)	--	5.938135753	144	5.73646	144	4.520077524	122	6.169094	166	3.415580011	99	4.837619521	128	0.956935582	0.172566307	normal	0.680356591	-0.554923128	normal	0.967958468	0.060242132	normal	0.886294335	-0.083636316	normal	--	--	Biological Process: transcription from RNA polymerase II promoter (GO:0006366);; 	K11313|0|pps:100971006|SUPT3H; suppressor of Ty 3 homolog (S. cerevisiae); K11313 transcription initiation protein SPT3 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	"Transcription initiation factor IID, 18kD subunit"	Transcription initiation protein SPT3 homolog GN=SUPT3H OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription initiation protein SPT3 homolog isoform X2 [Camelus ferus] 
ENSG00000196290(NIF3L1)	--	21.37526714	530	21.7190702	528	22.546663	547	11.71510615	324	10.76775513	280	13.3428201	341	0.009012718	-0.738064432	normal	0.000126746	-0.932804673	normal	0.02443522	-0.6876299	normal	2.15E-05	-0.785228685	normal	[S]	Function unknown	--	--	--	[R]	General function prediction only	NIF3 (NGG1p interacting factor 3)	Putative GTP cyclohydrolase 1 type 2 NIF3L1 GN=NIF3L1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: putative GTP cyclohydrolase 1 type 2 NIF3L1 isoform X4 [Galeopterus variegatus]
ENSG00000196296(ATP2A1)	--	0.711406034	49	1.27620497	54	0.594531	34	0.717923715	25	0.807571703	37	0.884533901	37	0.654723087	-0.958819378	normal	0.924214215	-0.548202357	normal	0.982154603	0.109048417	normal	0.444530341	-0.489367547	normal	[P]	Inorganic ion transport and metabolism	--	"K05853|0|pon:100453755|ATP2A1; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; K05853 Ca2+ transporting ATPase, sarcoplasmic/endoplasmic reticulum [EC:3.6.3.8] (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Pancreatic secretion (ko04972);; Alzheimer's disease (ko05010)	[P]	Inorganic ion transport and metabolism	"E1-E2 ATPase;; Cation transporting ATPase, C-terminus;; haloacid dehalogenase-like hydrolase;; Putative hydrolase of sodium-potassium ATPase alpha subunit;; Cation transporter/ATPase, N-terminus;; haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase"	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 GN=ATP2A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1 [Ochotona princeps]
ENSG00000196305(IARS)	--	99.5867421	7604	110.0634065	7922	110.055063	8046	86.994462	6626	81.858027	5983	103.7418106	7723	0.98516073	-0.229402886	normal	0.823759279	-0.426328209	normal	0.994974403	-0.067388879	normal	0.213702534	-0.23404362	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01870|0|hsa:3376|IARS, IARS1, ILERS, ILRS, IRS, PRO0785; isoleucyl-tRNA synthetase (EC:6.1.1.5); K01870 isoleucyl-tRNA synthetase [EC:6.1.1.5] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (I, L, M and V);; Anticodon-binding domain of tRNA;; tRNA synthetases class I (M)"	"Isoleucine--tRNA ligase, cytoplasmic GN=IARS OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: isoleucine--tRNA ligase, cytoplasmic isoform 1 [Ceratotherium simum simum]"
ENSG00000196312(MFSD14C)	--	16.785825	1452	10.073042	1692	20.786313	1735	12.946003	1547	18.206894	1647	14.255614	1568	0.982882653	0.060537417	normal	0.983703006	-0.060260977	normal	0.976442626	-0.154160133	normal	0.826877892	-0.055985548	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Major Facilitator Superfamily	Hippocampus abundant transcript-like protein 2 GN=HIATL2 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: hippocampus abundant transcript-like protein 1-like [Ceratotherium simum simum]
ENSG00000196313(POM121)	--	14.4778173	1961	13.84481264	1847	14.00387632	1881	17.721592	2212	18.57651606	2328	15.69570103	2101	0.980972617	0.142824184	normal	0.919865949	0.312252468	normal	0.979444143	0.15116982	normal	0.264858799	0.201917101	normal	--	--	--	"K14316|0|ptr:741888|POM121, POM121C; POM121 transmembrane nucleoporin; K14316 nuclear pore complex protein Nup121 (A)"	RNA transport (ko03013)	--	--	POM121 family	Nuclear envelope pore membrane protein POM 121 GN=POM121 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nuclear envelope pore membrane protein POM 121 [Galeopterus variegatus]
ENSG00000196323(ZBTB44)	--	6.683678	708	6.379714	797	6.531792754	713	8.197752727	1033	8.265642758	996	11.632785	1289	0.288056959	0.513259766	normal	0.901214493	0.299629977	normal	0.000127641	0.844635341	normal	0.002919645	0.560381936	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10515|0|ptr:451668|ZBTB44; zinc finger and BTB domain-containing protein 44; K10515 zinc finger and BTB domain-containing protein 44 (A)	--	--	--	"BTB/POZ domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies)"	Zinc finger and BTB domain-containing protein 44 GN=ZBTB44 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 44 isoform X5 [Canis lupus familiaris]
ENSG00000196335(STK31)	--	0.447184578	25	0.222053569	13	0.52709108	29	0.403302387	23	0.51168912	28	0.5244583	28	0.9867561	-0.142023134	normal	0.892447461	1.004279794	normal	0.98520275	-0.055948123	normal	0.830963033	0.218048648	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K16316|0|pps:100989639|STK31; serine/threonine kinase 31; K16316 serine/threonine-protein kinase 31 [EC:2.7.11.1] (A)	--	--	--	Tudor domain;; Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase 31 GN=STK31 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 31 isoform 1 [Ceratotherium simum simum]
ENSG00000196337(CGB7)	--	2.424452708	48	1.348269364	39	2.007065667	42	0.695922042	24	1.283333617	53	1.050862079	33	0.63489464	-0.985358498	normal	0.956285721	0.407492471	normal	0.972327489	-0.342278454	normal	0.746526681	-0.249988469	normal	--	--	--	"K10045|1.74494e-89|hsa:94027|CGB7, CG-beta-a, CGB6; chorionic gonadotropin, beta polypeptide 7; K10045 chorionic gonadotropin, beta polypeptide (A)"	--	--	--	Cystine-knot domain	Choriogonadotropin subunit beta (Precursor) GN=CGB8 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: lutropin subunit beta [Bos mutus]
ENSG00000196352(CD55)	--	27.2328754	1107	25.32446353	1038	22.99914286	975	20.33935586	795	20.86931786	758	32.65007313	1295	0.303320786	-0.507625068	normal	0.464105107	-0.474151241	normal	0.72266935	0.40064559	normal	0.76379774	-0.151477193	normal	--	--	--	"K04006|0|ptr:744672|CD55; CD55 molecule, decay accelerating factor for complement (Cromer blood group); K04006 decay accelerating factor (A)"	Complement and coagulation cascades (ko04610);; Hematopoietic cell lineage (ko04640);; Viral myocarditis (ko05416)	--	--	Sushi domain (SCR repeat)	Complement decay-accelerating factor (Precursor) GN=CD55 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: complement decay-accelerating factor isoform X4 [Balaenoptera acutorostrata scammoni]
ENSG00000196353(CPNE4)	--	3.174839645	103	2.874481258	106	1.93283543	107	1.94203954	103	5.592325605	211	3.93625792	166	0.970538303	-0.030379107	normal	0.003830712	0.961845067	normal	0.470163928	0.618212266	normal	0.250278286	0.583402133	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-4 GN=CPNE4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: copine-4 isoform X1 [Orycteropus afer afer]
ENSG00000196357(ZNF565)	--	2.097679	82	2.509246554	89	1.880001	67	2.36723	93	1.6876406	67	2.3134944	90	0.967870697	0.14816662	normal	0.915349627	-0.422761988	normal	0.923053899	0.409471287	normal	0.955681881	0.049089828	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:147929|ZNF565; zinc finger protein 565; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Probable zinc-binding domain"	Zinc finger protein 565 GN=ZNF565 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: uncharacterized protein LOC101329020 [Tursiops truncatus]
ENSG00000196358(NTNG2)	--	1.2520245	65	0.49945082	33	0.850652937	53	0.184111332	15	0.331908308	24	0.297021659	14	4.69E-05	-2.037538003	down	0.970812511	-0.456239947	normal	0.002669958	-1.82094226	down	0.004209308	-1.531298496	down	--	--	--	"K16359|0|hsa:84628|NTNG2, LHLL9381, Lmnt2, NTNG1, bA479K20.1; netrin G2; K16359 netrin-G2 (A)"	Axon guidance (ko04360);; Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Laminin N-terminal (Domain VI);; Laminin EGF-like (Domains III and V);; EGF-like domain	Netrin-G2 (Precursor) GN=NTNG2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	netrin-G2 precursor [Bos taurus] 
ENSG00000196361(ELAVL3)	--	0.00972052	1	0.019335116	2	0.019091719	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13208|0|cfa:484940|ELAVL3; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); K13208 ELAV like protein 2/3/4 (A)"	--	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	ELAV-like protein 3 GN=ELAVL3 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: ELAV-like protein 3 isoform X1 [Canis lupus familiaris]
ENSG00000196363(WDR5)	--	29.02851856	1514	25.901378	1419	25.9450541	1443	30.21863405	1613	28.5263772	1485	23.79935583	1303	0.983343138	0.060489495	normal	0.982700378	0.044115824	normal	0.973513411	-0.155354238	normal	0.970604033	-0.013617758	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14963|0|mcc:722123|uncharacterized WD repeat-containing protein ZC302.2-like; K14963 COMPASS component SWD3 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Nucleoporin Nup120/160;; Eukaryotic translation initiation factor eIF2A"	WD repeat-containing protein 5 GN=WDR5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 5 [Orcinus orca] 
ENSG00000196365(LONP1)	--	41.75121757	2909	46.41037748	3031	40.07107825	2888	36.37693211	2583	38.23923	2673	43.29840742	2989	0.976379017	-0.202194496	normal	0.976817952	-0.202652817	normal	0.989725265	0.041279465	normal	0.57391977	-0.119379422	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP-dependent peptidase activity (GO:0004176);; Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Biological Process: proteolysis (GO:0006508);; Molecular Function: four-way junction helicase activity (GO:0009378);; Molecular Function: ATPase activity (GO:0016887);; 	"K08675|0|pps:100976253|LONP1; lon peptidase 1, mitochondrial; K08675 Lon-like ATP-dependent protease [EC:3.4.21.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Lon protease (S16) C-terminal proteolytic domain;; ATP-dependent protease La (LON) domain;; ATPase family associated with various cellular activities (AAA);; AAA domain (dynein-related subfamily);; AAA domain (Cdc48 subfamily);; Subunit ChlI of Mg-chelatase;; AAA domain;; Holliday junction DNA helicase ruvB N-terminus;; PrkA AAA domain	"Lon protease homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03120} (Precursor) OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: lon protease homolog, mitochondrial [Pteropus alecto] "
ENSG00000196367(TRRAP)	--	13.9017129	3791	13.94813539	3782	14.74385204	4007	13.29025567	3545	14.28654992	3855	14.35766058	3882	0.988326022	-0.12757161	normal	0.991612483	0.006152502	normal	0.991576276	-0.05399313	normal	0.818326596	-0.058401749	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: kinase activity (GO:0016301);; 	"K08874|0|hsa:8295|TRRAP, PAF350/400, PAF400, STAF40, TR-AP, Tra1; transformation/transcription domain-associated protein; K08874 transformation/transcription domain-associated protein (A)"	HTLV-I infection (ko05166)	[TBLD]	"Signal transduction mechanisms;; Chromatin structure and dynamics;; Replication, recombination and repair;; Cell cycle control, cell division, chromosome partitioning"	FAT domain;; Phosphatidylinositol 3- and 4-kinase	Transformation/transcription domain-associated protein GN=TRRAP OS=Homo sapiens (Human) PE=1 SV=3	BDLT	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair;; Signal transduction mechanisms"	PREDICTED: transformation/transcription domain-associated protein isoform X1 [Lipotes vexillifer]
ENSG00000196368(NUDT11)	--	6.04021	211	3.74068	132	4.15388	145	1.22364	43	1.95157	68	1.37198	48	1.11E-15	-2.284840137	down	0.031244951	-0.962704724	normal	1.54E-06	-1.573285163	down	7.56E-05	-1.638729093	down	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K07766|6.41404e-89|pps:100977832|diphosphoinositol polyphosphate phosphohydrolase 3-beta; K07766 diphosphoinositol-polyphosphate diphosphatase [EC:3.6.1.52] (A)	--	[T]	Signal transduction mechanisms	NUDIX domain	Diphosphoinositol polyphosphate phosphohydrolase 3-beta GN=NUDT11 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: diphosphoinositol polyphosphate phosphohydrolase 3-beta-like [Vicugna pacos] 
ENSG00000196369(SRGAP2B)	--	5.077954	548	5.836089	537	6.16541	595	4.465627	461	5.05683	492	4.738526	455	0.908376397	-0.279386055	normal	0.960212849	-0.147256902	normal	0.742941543	-0.394165361	normal	0.20426397	-0.275829566	normal	--	--	--	--	--	[Z]	Cytoskeleton	"Fes/CIP4, and EFC/F-BAR homology domain"	SLIT-ROBO Rho GTPase-activating protein 2B GN=SRGAP2B OS=Homo sapiens (Human) PE=3 SV=1	T	Signal transduction mechanisms	PREDICTED: SLIT-ROBO Rho GTPase-activating protein 2 isoform 2 [Ceratotherium simum simum]
ENSG00000196371(FUT4)	--	1.89395	171	1.7928	164	1.61506	147	2.02418	185	1.38635	125	1.6491	150	0.964839575	0.081988363	normal	0.855210839	-0.408861418	normal	0.96775822	0.020644652	normal	0.865024612	-0.089638684	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: fucosyltransferase activity (GO:0008417);; Cellular Component: membrane (GO:0016020);; 	"K07632|0|hsa:2526|FUT4, CD15, ELFT, FCT3A, FUC-TIV, FUTIV, LeX, SSEA-1; fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) (EC:2.4.1.-); K07632 galactoside alpha-1,3-fucosyltransferase 4 [EC:2.4.1.-] (A)"	Other types of O-glycan biosynthesis (ko00514);; Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Glycosyltransferase family 10 (fucosyltransferase)	"Alpha-(1,3)-fucosyltransferase 4 GN=FUT4 OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: alpha-(1,3)-fucosyltransferase 4 [Loxodonta africana]"
ENSG00000196372(ASB13)	--	10.68188	508	7.87259	383	8.905162	427	12.6022	603	14.96747	708	13.77842	657	0.943440279	0.215897362	normal	0.000338232	0.862436375	normal	0.079927425	0.611606495	normal	0.001828824	0.557490306	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10335|0|ptr:737798|ASB13; ankyrin repeat and SOCS box containing 13; K10335 ankyrin repeat and SOCS box protein 13 (A)	--	[R]	General function prediction only	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 13 GN=ASB13 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 13 [Oryctolagus cuniculus]
ENSG00000196376(SLC35F1)	--	0.149049433	11	0.257023194	19	0.194974286	12	0.014935205	1	0.078777064	5	0.029701717	2	--	--	--	--	--	--	--	--	--	--	--	--	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15287|0|ptr:472111|SLC35F1; solute carrier family 35, member F1; K15287 solute carrier family 35, member F1/2 (A)"	--	[S]	Function unknown	Eukaryotic protein of unknown function (DUF914);; EamA-like transporter family	Solute carrier family 35 member F1 GN=SLC35F1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: solute carrier family 35 member F1 [Ceratotherium simum simum]
ENSG00000196378(ZNF34)	--	2.153185021	87	1.59158499	83	2.6400835	101	1.693888981	82	1.98095617	91	2.35790434	115	0.970264229	-0.114146868	normal	0.968498355	0.109424152	normal	0.961750306	0.176508789	normal	0.926386446	0.067928801	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:464472|ZNF34; zinc finger protein 34; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; XPA protein N-terminal;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 34 GN=ZNF34 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 34 isoform X2 [Ursus maritimus]
ENSG00000196387(ZNF140)	--	4.235698	170	5.326718934	170	4.07966	166	5.133658	201	5.290819244	219	6.588640204	232	0.947787929	0.209089125	normal	0.886227217	0.341288482	normal	0.703532575	0.471004373	normal	0.282052368	0.344949062	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:452394|ZNF140; zinc finger protein 140; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 140 GN=ZNF140 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 140 isoform X2 [Galeopterus variegatus] 
ENSG00000196388(INCA1)	--	3.512604788	64	2.064460018	39	2.131852745	36	0.883825567	15	1.164475038	19	0.948658997	17	6.89E-05	-2.015685212	down	0.751132929	-1.002108043	normal	0.785968166	-1.026665695	normal	0.005385442	-1.467738419	down	--	--	--	--	--	--	--	INCA1	Protein INCA1 GN=INCA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein INCA1 [Vicugna pacos]
ENSG00000196391(ZNF774)	--	0.55658302	54	0.545789988	51	0.5824415	77	1.074684299	81	1.607161959	97	2.252829082	80	0.874358339	0.541477405	normal	0.225952597	0.886695057	normal	0.973017031	0.04596442	normal	0.316434747	0.483041297	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Prokaryotic RING finger family 1;; Zinc-finger of C2H2 type;; LIM domain"	Zinc finger protein 774 GN=ZNF774 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	hypothetical protein PANDA_008504 [Ailuropoda melanoleuca]
ENSG00000196396(PTPN1)	--	19.51957355	1698	19.185476	1602	19.13353071	1645	23.933797	1962	22.6893697	1907	19.0651082	1584	0.974296316	0.177506808	normal	0.96068002	0.2298051	normal	0.983640752	-0.0627479	normal	0.57478948	0.119303003	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K05696|0|ptr:469970|PTPN1; protein tyrosine phosphatase, non-receptor type 1; K05696 tyrosine-protein phosphatase non-receptor type 1 [EC:3.1.3.48] (A)"	Adherens junction (ko04520);; Insulin signaling pathway (ko04910)	[T]	Signal transduction mechanisms	"Protein-tyrosine phosphatase;; Dual specificity phosphatase, catalytic domain"	Tyrosine-protein phosphatase non-receptor type 1 GN=PTPN1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 1 [Galeopterus variegatus]
ENSG00000196405(EVL)	--	17.28084249	767	10.45091379	570	14.86023443	726	18.18831615	830	17.55779454	928	14.478702	795	0.974005601	0.082892855	normal	0.016705083	0.680308638	normal	0.969575693	0.12245005	normal	0.129522915	0.286416811	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	WH1 domain;; VASP tetramerisation domain	Ena/VASP-like protein GN=EVL OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ena/VASP-like protein isoform 1 [Ceratotherium simum simum]
ENSG00000196406(SPANXD)	--	0	0	0.105029	1	0.206342	1	0.102567	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Sperm protein associated with nucleus, mapped to X chromosome"	Sperm protein associated with the nucleus on the X chromosome D GN=SPANXD OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000196408(NOXO1)	--	0.97765	11	0.295067047	7	0.6775633	9	1.355609177	17	0.754707661	17	0.889081	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17934|0|pps:100967369|NOXO1; NADPH oxidase organizer 1; K17934 NADPH oxidase organizer 1 (A)	--	--	--	SH3 domain;; Variant SH3 domain;; Variant SH3 domain;; PX domain	NADPH oxidase organizer 1 GN=NOXO1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: NADPH oxidase organizer 1 [Odobenus rosmarus divergens]
ENSG00000196411(EPHB4)	--	23.87521403	2020	22.31597873	1924	23.78590421	2066	20.26368172	1715	21.95155065	1846	22.25599287	1884	0.946173566	-0.266758469	normal	0.984117845	-0.081067745	normal	0.98047727	-0.141224436	normal	0.397941566	-0.163226249	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05113|0|hsa:2050|EPHB4, HTK, MYK1, TYRO11; EPH receptor B4 (EC:2.7.10.1); K05113 Eph receptor B4 [EC:2.7.10.1] (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Ephrin receptor ligand binding domain;; Protein kinase domain;; Fibronectin type III domain;; Ephrin type-A receptor 2 transmembrane domain;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; GCC2 and GCC3	Ephrin type-B receptor 4 (Precursor) GN=EPHB4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ephrin type-B receptor 4 [Oryctolagus cuniculus]
ENSG00000196415(PRTN3)	--	1.435545162	22	0.698544624	11	0.796850128	12	0	0	0.314235871	4	0.196477278	3	0.000951672	-3.951689597	down	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01350|2.44107e-170|hsa:5657|PRTN3, ACPA, AGP7, C-ANCA, CANCA, MBN, MBT, NP-4, NP4, P29, PR-3, PR3; proteinase 3 (EC:3.4.21.76); K01350 myeloblastin [EC:3.4.21.76] (A)"	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Myeloblastin (Precursor) GN=PRTN3 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: myeloblastin [Myotis davidii] 
ENSG00000196417(ZNF765)	--	3.963018	362	3.457066	315	4.318482233	383	4.120426	367	3.164776	278	4.015297	355	0.968926862	-0.01099555	normal	0.944701954	-0.200667209	normal	0.962564115	-0.117335452	normal	0.755021989	-0.105229448	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:91661|ZNF765; zinc finger protein 765; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 765 GN=ZNF765 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 347-like [Galeopterus variegatus]
ENSG00000196418(ZNF124)	--	3.580594193	124	3.160292945	116	2.823688971	109	3.833405729	149	4.5539491	151	3.560307109	118	0.948851597	0.231520238	normal	0.903332665	0.354931399	normal	0.966849916	0.104769915	normal	0.590946568	0.23831912	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:103785520|ZNF124; zinc finger protein 124; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 124 GN=ZNF124 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 709 [Oryctolagus cuniculus]
ENSG00000196419(XRCC6)	--	126.711151	6078	128.503951	6214	130.5961811	6263	131.73151	6330	125.1729395	5988	105.329153	5068	0.99439247	0.027769683	normal	0.993495536	-0.074856018	normal	0.954980446	-0.313644441	normal	0.611223041	-0.11567798	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Biological Process: double-strand break repair via nonhomologous end joining (GO:0006303);; 	K10884|0|ptr:465902|XRCC6; X-ray repair complementing defective repair in Chinese hamster cells 6; K10884 ATP-dependent DNA helicase 2 subunit 1 (A)	Non-homologous end-joining (ko03450)	[L]	"Replication, recombination and repair"	Ku70/Ku80 N-terminal alpha/beta domain;; Ku70/Ku80 beta-barrel domain;; Ku70/Ku80 C-terminal arm;; SAP domain	X-ray repair cross-complementing protein 6 GN=XRCC6 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: X-ray repair cross-complementing protein 6 isoform 3 [Dasypus novemcinctus]
ENSG00000196420(S100A5)	--	0.209028937	2	0.201936	2	0.099949	0	1.142288	7	0.814116187	3	0.407722	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A5 GN=S100A5 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein S100-A5 [Erinaceus europaeus]
ENSG00000196421(LINC00176)	--	0.377019392	11	0.233483452	8	0.237214024	10	0.127916501	5	0.144567341	4	0.805395546	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative uncharacterized protein encoded by LINC00176 GN=LINC00176 OS=Homo sapiens (Human) PE=5 SV=1	R	General function prediction only	PREDICTED: uncharacterized protein LOC103558334 [Equus przewalskii]
ENSG00000196422(PPP1R26)	--	10.38525324	1172	9.430891143	1080	10.59926419	1222	10.58612917	1198	10.30318622	1148	9.539425697	1072	0.981486338	0.000822009	normal	0.978733781	0.066574347	normal	0.961860802	-0.196970363	normal	0.874141821	-0.044797153	normal	--	--	--	"K17565|0|hsa:9858|PPP1R26, KIAA0649; protein phosphatase 1, regulatory subunit 26; K17565 protein phosphatase 1 regulatory subunit 26 (A)"	--	--	--	--	Protein phosphatase 1 regulatory subunit 26 GN=PPP1R26 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 26 [Galeopterus variegatus]
ENSG00000196427(NBPF4)	--	0.06458604	5	0.05340271	4	0.0255482	1	0.05239	4	0.187374726	13	0.012831449	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220)	Neuroblastoma breakpoint family member 4 GN=NBPF4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: neuroblastoma breakpoint family member 6-like [Leptonychotes weddellii]
ENSG00000196428(TSC22D2)	--	12.02438837	646	14.7978219	753	13.4129638	687	21.198881	1140	17.9869761	1058	14.9885958	774	0.000773231	0.787168652	normal	0.488590666	0.468394223	normal	0.962321555	0.163392986	normal	0.05071055	0.4883674	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	TSC-22/dip/bun family	TSC22 domain family protein 2 GN=TSC22D2 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: TSC22 domain family protein 2 [Galeopterus variegatus]
ENSG00000196433(ASMT)	--	0.665851473	3	0.193796906	3	0.127127164	1	0.11137929	2	0	0	0.324153338	2	--	--	--	--	--	--	--	--	--	--	--	--	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: O-methyltransferase activity (GO:0008171);; 	"K00543|0|hsa:438|ASMT, ASMTY, HIOMT, HIOMTY; acetylserotonin O-methyltransferase (EC:2.1.1.4); K00543 acetylserotonin N-methyltransferase [EC:2.1.1.4] (A)"	Tryptophan metabolism (ko00380)	[R]	General function prediction only	O-methyltransferase;; Methyltransferase domain;; Protein of unknown function (DUF1725)	Acetylserotonin O-methyltransferase GN=ASMT OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: acetylserotonin O-methyltransferase [Ursus maritimus]
ENSG00000196436(NPIPB15)	--	0.219134	5	0.0878613	2	0.215345	4	0.129442	3	0.339025	7	0.513607	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B15 (Precursor) GN=NPIPB15 OS=Homo sapiens (Human) PE=3 SV=3	R	General function prediction only	--
ENSG00000196437(ZNF569)	--	4.930497005	277	4.566723254	315	4.8158951	273	3.478186549	215	3.892761572	235	3.279910792	232	0.808407876	-0.393894038	normal	0.703214803	-0.441653237	normal	0.933680254	-0.241614014	normal	0.176210516	-0.364029722	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:468853|ZNF569; zinc finger protein 569; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Transposase zinc-ribbon domain"	Zinc finger protein 569 GN=ZNF569 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 569 [Tupaia chinensis]
ENSG00000196440(ARMCX4)	--	0.107032	18	0.0961637	17	0.0627877	10	0.298963	51	0.314294	52	0.332697	56	0.089830092	1.397980395	normal	0.034855838	1.511138489	normal	3.23E-05	2.313057845	up	0.000359183	1.799238891	up	--	--	--	--	--	--	--	Armadillo-like;; Snare region anchored in the vesicle membrane C-terminus	Armadillo repeat-containing X-linked protein 4 GN=ARMCX4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: armadillo repeat-containing X-linked protein 4 [Galeopterus variegatus]
ENSG00000196449(YRDC)	--	9.42598	237	8.94375	227	9.82547	241	9.74087	242	8.98462	234	8.21646	204	0.967066319	-0.000707735	normal	0.965717956	0.022243721	normal	0.933682459	-0.247068274	normal	0.868332882	-0.073683788	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: double-stranded RNA binding (GO:0003725);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Telomere recombination	"YrdC domain-containing protein, mitochondrial (Precursor) GN=YRDC OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: yrdC domain-containing protein, mitochondrial isoform X1 [Pteropus alecto] "
ENSG00000196453(ZNF777)	--	8.68957	632	8.9992	658	7.35787	551	9.08619	665	8.72298	634	10.19724	753	0.973745645	0.042496801	normal	0.971436638	-0.074856018	normal	0.589484244	0.44126606	normal	0.582989231	0.135412039	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:27153|ZNF777; zinc finger protein 777; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Zinc finger protein;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger"	Zinc finger protein 777 GN=ZNF777 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 777 [Oryctolagus cuniculus]
ENSG00000196455(PIK3R4)	--	6.773708702	627	7.2227642	665	10.85623755	711	9.890204335	667	7.839766104	685	7.467380202	643	0.973019226	0.058250655	normal	0.974217163	0.021275419	normal	0.96329441	-0.152979946	normal	0.939719267	-0.026883779	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08333|0|hsa:30849|PIK3R4, VPS15, p150; phosphoinositide-3-kinase, regulatory subunit 4 (EC:2.7.11.1); K08333 phosphoinositide-3-kinase, regulatory subunit 4 [EC:2.7.11.1] (A)"	Regulation of autophagy (ko04140)	[T]	Signal transduction mechanisms	"Protein kinase domain;; WD domain, G-beta repeat;; HEAT repeat;; Protein tyrosine kinase"	Phosphoinositide 3-kinase regulatory subunit 4 GN=PIK3R4 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: phosphoinositide 3-kinase regulatory subunit 4 [Galeopterus variegatus] 
ENSG00000196456(ZNF775)	--	62.62522803	3288	62.27839734	3551	59.55298022	3530	62.79813384	3628	67.92338771	3652	79.33615435	4337	0.988722929	0.111082467	normal	0.991172406	0.019026857	normal	0.957043335	0.288626077	normal	0.487926017	0.143334339	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Double zinc ribbon;; Methyl-CpG binding domain"	Zinc finger protein 775 GN=ZNF775 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 775 [Oryctolagus cuniculus]
ENSG00000196459(TRAPPC2)	--	6.340891638	203	5.887617	217	5.630031	205	7.738020525	271	8.26517733	259	7.27747504	244	0.828050774	0.383461624	normal	0.936483802	0.232346786	normal	0.935597918	0.241332058	normal	0.348634804	0.286918848	normal	[N]	Cell motility	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Cellular Component: TRAPP complex (GO:0030008);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Sedlin, N-terminal conserved region;; Sybindin-like family"	Trafficking protein particle complex subunit 2 protein TRAPPC2P1 GN=TRAPPC2P1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 2-like [Tursiops truncatus]
ENSG00000196465(MYL6B)	--	45.102248	820	40.89982	760	44.132309	850	39.964807	783	40.821003	803	45.382832	880	0.97288473	-0.097257349	normal	0.974766326	0.057861995	normal	0.977255218	0.041676364	normal	1	0.000523306	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	--	"K12751|2.42685e-119|hsa:140465|MYL6B, MLC1SA; myosin, light chain 6B, alkali, smooth muscle and non-muscle; K12751 myosin light chain 6 (A)"	Vascular smooth muscle contraction (ko04270);; Oxytocin signaling pathway (ko04921)	[Z]	Cytoskeleton	EF-hand domain;; EF-hand domain pair;; EF hand	Myosin light chain 6B GN=MYL6B OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: myosin light chain 6B [Felis catus]
ENSG00000196470(SIAH1)	--	15.716236	465	15.864095	479	12.684555	380	14.575462	447	14.053114	418	15.47414	476	0.967275693	-0.087493256	normal	0.940559681	-0.217214477	normal	0.877894048	0.315546454	normal	0.999834061	-0.003008331	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: ubiquitin-dependent protein catabolic process (GO:0006511);; Biological Process: multicellular organismal development (GO:0007275);; 	K04506|0|pps:100979152|SIAH1; siah E3 ubiquitin protein ligase 1; K04506 E3 ubiquitin-protein ligase SIAH1 [EC:6.3.2.19] (A)	p53 signaling pathway (ko04115);; Ubiquitin mediated proteolysis (ko04120);; Wnt signaling pathway (ko04310)	[R]	General function prediction only	Seven in absentia protein family	E3 ubiquitin-protein ligase SIAH1 GN=SIAH1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase SIAH1 [Galeopterus variegatus]
ENSG00000196476(C20orf96)	--	10.47806276	378	11.9066511	432	12.90682721	451	7.299842404	249	8.962110275	312	9.530436821	343	0.11923	-0.629893193	normal	0.505657068	-0.488888404	normal	0.744528767	-0.401660916	normal	0.019504801	-0.500210015	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4618)	Uncharacterized protein C20orf96 GN=C20orf96 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C20orf96 homolog isoform X2 [Galeopterus variegatus]
ENSG00000196482(ESRRG)	--	0.025224012	2	0.020534761	1	0	0	0.020329366	1	0.019730726	0	0.024958808	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K08554|0|mcc:708176|ESRRG; estrogen-related receptor gamma; K08554 estrogen-related receptor gamma (A)	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Estrogen-related receptor gamma GN=ESRRG OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: estrogen-related receptor gamma-like isoform X1 [Leptonychotes weddellii]
ENSG00000196497(IPO4)	--	28.11352056	2038	29.75815438	2189	31.08779	2287	30.82587839	2221	32.01713885	2073	24.18822964	1751	0.985095742	0.093155794	normal	0.984413679	-0.099907457	normal	0.779381288	-0.393270603	normal	0.535298568	-0.129548921	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	HEAT repeats;; HEAT-like repeat;; HEAT repeat;; Vacuolar 14 Fab1-binding region;; Importin-beta N-terminal domain;; rRNA processing/ribosome biogenesis	Importin-4 GN=IPO4 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	Importin-4 [Tupaia chinensis]
ENSG00000196498(NCOR2)	--	59.0926304	8877	63.94376925	8855	58.39075458	9422	84.35704324	12055	82.95355868	12311	61.46941778	9500	0.885602023	0.410594098	normal	0.795641461	0.453891172	normal	0.996065823	0.003602164	normal	0.10529815	0.296974646	normal	--	--	--	K06065|0|mcf:102140503|NCOR2; nuclear receptor corepressor 2; K06065 nuclear receptor co-repressor 2 (A)	Notch signaling pathway (ko04330);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	Myb-like DNA-binding domain;; Myb-like DNA-binding domain	Nuclear receptor corepressor 2 GN=NCOR2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: nuclear receptor corepressor 2 isoform X1 [Galeopterus variegatus]
ENSG00000196502(SULT1A1)	--	2.687513746	74	1.13829249	46	0.999217093	37	1.068650017	23	1.5282634	40	0.4767176	14	0.000547791	-1.651798927	down	0.975199473	-0.215457525	normal	0.429519053	-1.319631842	normal	0.145783211	-1.050347504	normal	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K01014|0|hsa:6817|SULT1A1, HAST1/HAST2, P-PST, PST, ST1A1, ST1A3, STP, STP1, TSPST1; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 (EC:2.8.2.1); K01014 aryl sulfotransferase [EC:2.8.2.1] (A)"	Chemical carcinogenesis (ko05204)	[R]	General function prediction only	Sulfotransferase domain	Sulfotransferase 1A1 GN=SULT1A1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: sulfotransferase 1A1 isoform X1 [Equus caballus] 
ENSG00000196503(ARL9)	--	0.039625855	1	0.0790823	2	0	0	0	0	0	0	0.039256127	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	K07957|7.08666e-48|ptr:736733|ARL9; ADP-ribosylation factor-like 9; K07957 ADP-ribosylation factor-like protein 9 (A)	--	[R]	General function prediction only	ADP-ribosylation factor family	ADP-ribosylation factor-like protein 9 GN=ARL9 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 9 [Mustela putorius furo] 
ENSG00000196504(PRPF40A)	--	33.0201596	3109	32.41813599	3152	35.33352405	3221	27.0262563	2516	26.51968334	2508	22.21940941	1959	0.906823925	-0.335965983	normal	0.892673974	-0.350967509	normal	0.00242255	-0.725241474	normal	0.001715582	-0.463154094	normal	[A]	RNA processing and modification	Molecular Function: protein binding (GO:0005515);; 	"K12821|0|hsa:55660|PRPF40A, FBP-11, FBP11, FLAF1, FNBP3, HIP-10, HIP10, HYPA, NY-REN-6, Prp40; PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae); K12821 pre-mRNA-processing factor 40 (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	FF domain;; WW domain	Pre-mRNA-processing factor 40 homolog A GN=HSPC225 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: pre-mRNA-processing factor 40 homolog A isoform X3 [Galeopterus variegatus]
ENSG00000196505(GDAP2)	--	3.68396901	275	4.399311019	397	4.261090009	348	3.15526144	283	3.479457044	290	4.010684154	367	0.967442438	0.010480451	normal	0.576447647	-0.472397836	normal	0.966855873	0.068113057	normal	0.714727918	-0.138269863	normal	[R]	General function prediction only	--	--	--	[BK]	Chromatin structure and dynamics;; Transcription	Divergent CRAL/TRIO domain;; Macro domain;; CRAL/TRIO domain	Ganglioside-induced differentiation-associated protein 2 GN=GDAP2 OS=Homo sapiens (Human) PE=1 SV=1	BK	Chromatin structure and dynamics;; Transcription	PREDICTED: ganglioside-induced differentiation-associated protein 2 [Ochotona princeps]
ENSG00000196507(TCEAL3)	--	9.604972	263	7.694053919	220	11.2779095	322	10.31999616	290	10.0562563	273	7.996266177	219	0.962087741	0.109548251	normal	0.911110715	0.288189596	normal	0.337869564	-0.561205089	normal	0.887347976	-0.063231272	normal	--	--	--	--	--	--	--	Brain expressed X-linked like family	Transcription elongation factor A protein-like 3 GN=TCEAL3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription elongation factor A protein-like 3 isoform X1 [Sus scrofa] 
ENSG00000196510(ANAPC7)	--	26.30986149	1233	23.18410809	1184	25.94880014	1294	27.97387448	1391	26.18065005	1294	23.29674273	1213	0.974528246	0.142949585	normal	0.977368604	0.106611697	normal	0.97840828	-0.101427053	normal	0.853525777	0.049451824	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K03354|0|ptr:467128|ANAPC7; anaphase promoting complex subunit 7; K03354 anaphase-promoting complex subunit 7 (A)	Cell cycle (ko04110);; Oocyte meiosis (ko04114);; Ubiquitin mediated proteolysis (ko04120);; Progesterone-mediated oocyte maturation (ko04914);; HTLV-I infection (ko05166)	[DO]	"Cell cycle control, cell division, chromosome partitioning;; Posttranslational modification, protein turnover, chaperones"	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; ChAPs (Chs5p-Arf1p-binding proteins)"	Anaphase-promoting complex subunit 7 GN=ANAPC7 OS=Homo sapiens (Human) PE=1 SV=4	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: anaphase-promoting complex subunit 7 isoform X2 [Equus przewalskii]
ENSG00000196511(TPK1)	--	1.440063401	32	2.210973698	47	0.802899947	21	2.922909753	40	1.788962586	34	3.731500284	53	0.977540609	0.279091991	normal	0.952790639	-0.470668298	normal	0.157700067	1.267970846	normal	0.66095326	0.323347791	normal	[H]	Coenzyme transport and metabolism	Molecular Function: thiamine diphosphokinase activity (GO:0004788);; Molecular Function: ATP binding (GO:0005524);; Biological Process: thiamine diphosphate biosynthetic process (GO:0009229);; Molecular Function: thiamine binding (GO:0030975);; 	K00949|0|pps:100974231|TPK1; thiamin pyrophosphokinase 1; K00949 thiamine pyrophosphokinase [EC:2.7.6.2] (A)	Thiamine metabolism (ko00730)	[H]	Coenzyme transport and metabolism	"Thiamin pyrophosphokinase, catalytic domain;; Thiamin pyrophosphokinase, vitamin B1 binding domain"	Thiamin pyrophosphokinase 1 GN=TPK1 OS=Homo sapiens (Human) PE=1 SV=1	H	Coenzyme transport and metabolism	PREDICTED: thiamin pyrophosphokinase 1 isoform X1 [Tupaia chinensis] 
ENSG00000196517(SLC6A9)	--	5.453332464	283	6.297555775	328	6.83864057	371	3.838587535	210	3.676383184	198	8.010051127	435	0.680393516	-0.458344202	normal	0.028271626	-0.745150843	normal	0.939504882	0.220474001	normal	0.747209522	-0.238821305	normal	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05038|0|ptr:456520|SLC6A9; solute carrier family 6 (neurotransmitter transporter, glycine), member 9; K05038 solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium- and chloride-dependent glycine transporter 1 GN=SLC6A9 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: sodium- and chloride-dependent glycine transporter 1 isoform X1 [Vicugna pacos]
ENSG00000196526(AFAP1)	--	16.92934509	2509	16.00023813	2383	18.9989671	2823	22.1779352	3277	17.80717076	2626	17.83283979	2637	0.884660366	0.354240655	normal	0.984923304	0.118589696	normal	0.986832786	-0.106563921	normal	0.568635952	0.124912986	normal	--	--	--	"K18616|0|hsa:60312|AFAP1, AFAP, AFAP-110, AFAP110; actin filament associated protein 1; K18616 actin filament associated protein 1 (A)"	--	--	--	PH domain	Actin filament-associated protein 1 GN=AFAP1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: actin filament-associated protein 1 [Galeopterus variegatus]
ENSG00000196531(NACA)	--	580.2632227	7621	587.6678899	7760	576.2239217	7758	654.4279738	8940	665.4251395	8831	588.0599071	8073	0.989926109	0.199425103	normal	0.992087208	0.165063434	normal	0.995209311	0.049119287	normal	0.537168297	0.138041377	normal	[K]	Transcription	--	--	--	[K]	Transcription	NAC domain	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form GN=NACA OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: nascent polypeptide-associated complex subunit alpha, muscle-specific form isoform X1 [Panthera tigris altaica]"
ENSG00000196535(MYO18A)	--	15.35197662	2736	12.47271342	2370	14.57540841	2747	13.58855588	2603	15.23720916	2877	13.55413284	2452	0.986843635	-0.102666063	normal	0.960106135	0.258101929	normal	0.980381566	-0.172089038	normal	0.985612711	-0.00669052	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10362|0|hsa:399687|MYO18A, MYSPDZ, SPR210; myosin XVIIIA; K10362 myosin XVIII (A)"	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; PDZ domain (Also known as DHR or GLGF)	Unconventional myosin-XVIIIa GN=MYO18A OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: unconventional myosin-XVIIIa isoform X1 [Chrysochloris asiatica]
ENSG00000196542(SPTSSB)	--	0.328353491	15	0.265925038	4	0.204773416	7	0	0	0.148105057	6	0.064853814	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	--
ENSG00000196544(BORCS6)	--	5.04168	230	5.66733	265	6.52362	307	5.86266	269	6.03648	275	8.43156	388	0.948207946	0.193941214	normal	0.965939824	0.031834365	normal	0.869825225	0.328085864	normal	0.628904125	0.196998324	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2365)	Uncharacterized protein C17orf59 GN=C17orf59 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C17orf59 homolog [Ceratotherium simum simum]
ENSG00000196547(MAN2A2)	--	16.47621847	1460	15.28600353	1402	17.1845826	1538	13.91897212	1470	17.72938057	1560	16.07756765	1519	0.983663005	-0.020962493	normal	0.977231628	0.132497588	normal	0.984066242	-0.026199154	normal	0.926926189	0.027120441	normal	--	--	Molecular Function: alpha-mannosidase activity (GO:0004559);; Biological Process: mannose metabolic process (GO:0006013);; 	"K01231|0|hsa:4122|MAN2A2, MANA2X; mannosidase, alpha, class 2A, member 2 (EC:3.2.1.114); K01231 alpha-mannosidase II [EC:3.2.1.114] (A)"	N-Glycan biosynthesis (ko00510)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolases family 38 N-terminal domain;; Glycosyl hydrolases family 38 C-terminal domain;; Alpha mannosidase, middle domain"	Alpha-mannosidase 2x GN=MAN2A2 OS=Homo sapiens (Human) PE=2 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: alpha-mannosidase 2x isoform 1 [Trichechus manatus latirostris] 
ENSG00000196549(MME)	--	0.337182588	12	0.103961591	6	0.325077173	4	0.035847163	2	0.022120294	1	0.15605351	4	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K01389|0|hsa:4311|MME, CALLA, CD10, NEP, SFE; membrane metallo-endopeptidase (EC:3.4.24.11); K01389 neprilysin [EC:3.4.24.11] (A)"	Renin-angiotensin system (ko04614);; Hematopoietic cell lineage (ko04640);; Protein digestion and absorption (ko04974);; Alzheimer's disease (ko05010)	[E]	Amino acid transport and metabolism	Peptidase family M13;; Peptidase family M13	Neprilysin GN=MME OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: neprilysin isoform X1 [Oryctolagus cuniculus] 
ENSG00000196550(FAM72A)	--	7.289606	155	5.39880501	115	7.366604	180	5.619484	140	4.997435	117	4.960742	112	0.957098018	-0.175838571	normal	0.968235015	0.003403736	normal	0.250376343	-0.685420405	normal	0.44182822	-0.307627949	normal	--	--	--	--	--	--	--	FAM72 protein	Protein FAM72A GN=FAM72A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM72A [Canis lupus familiaris]
ENSG00000196557(CACNA1H)	--	8.626654904	1198	5.517803809	781	5.8663778	853	8.248681622	1225	12.07503851	1841	6.753576083	1018	0.981733455	0.001319904	normal	2.28E-10	1.214091866	up	0.938907819	0.246428065	normal	0.346302446	0.506609402	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04855|0|hsa:8912|CACNA1H, CACNA1HB, Cav3.2, ECA6, EIG6; calcium channel, voltage-dependent, T type, alpha 1H subunit; K04855 voltage-dependent calcium channel T type alpha-1H (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; Circadian entrainment (ko04713)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Polycystin cation channel	Voltage-dependent T-type calcium channel subunit alpha-1H GN=CACNA1H OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent T-type calcium channel subunit alpha-1H [Galeopterus variegatus]
ENSG00000196562(SULF2)	--	12.32244795	1058	11.945719	1153	11.81503699	1055	12.99673137	1240	17.48617426	1591	13.33475087	1158	0.961477201	0.197902561	normal	0.601528061	0.442618624	normal	0.974326894	0.125928461	normal	0.265120902	0.267174731	normal	[P]	Inorganic ion transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; 	"K14607|0|hsa:55959|SULF2, HSULF-2; sulfatase 2; K14607 extracellular sulfatase Sulf [EC:3.1.6.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Sulfatase;; Sulfatase protein;; Type I phosphodiesterase / nucleotide pyrophosphatase	Extracellular sulfatase Sulf-2 (Precursor) GN=SULF2 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: extracellular sulfatase Sulf-2 isoform X1 [Equus caballus]
ENSG00000196565(HBG2)	--	0	0	0.4515424	6	0.241892979	2	0.301841	3	0.461382	3	0.716341001	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; 	"K13824|1.90097e-104|ptr:450979|HBG2, HBG1; hemoglobin, gamma G; K13824 hemoglobin subunit gamma (A)"	--	[C]	Energy production and conversion	Globin	Hemoglobin subunit gamma-2 GN=HBG2 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	RecName: Full=Hemoglobin subunit epsilon; AltName: Full=Epsilon-globin; AltName: Full=Hemoglobin epsilon chain [Bradypus tridactylus] 
ENSG00000196569(LAMA2)	--	0.47624297	36	0.415199991	27	0.27230877	33	0.569391255	24	0.51016411	33	0.637203893	32	0.956395602	-0.585007591	normal	0.980248748	0.255137422	normal	0.983775558	-0.050342634	normal	0.901560107	-0.129363154	normal	--	--	Molecular Function: receptor binding (GO:0005102);; Biological Process: cell adhesion (GO:0007155);; Biological Process: regulation of cell adhesion (GO:0030155);; Biological Process: regulation of cell migration (GO:0030334);; Biological Process: regulation of embryonic development (GO:0045995);; 	"K05637|0|hsa:3908|LAMA2, LAMM; laminin, alpha 2; K05637 laminin, alpha 1/2 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	[W]	Extracellular structures	Laminin G domain;; Laminin G domain;; Laminin EGF-like (Domains III and V);; Laminin N-terminal (Domain VI);; Laminin Domain I;; Laminin B (Domain IV);; Laminin Domain II;; Concanavalin A-like lectin/glucanases superfamily	Laminin subunit alpha-2 (Precursor) GN=LAMA2 OS=Homo sapiens (Human) PE=1 SV=4	W	Extracellular structures	PREDICTED: laminin subunit alpha-2 [Equus caballus]
ENSG00000196576(PLXNB2)	--	52.4601618	6277	46.59994601	6268	52.82328149	6526	65.07052606	7701	60.05100992	7578	70.54709292	8516	0.978523853	0.264079886	normal	0.980978811	0.252329965	normal	0.914495101	0.37560911	normal	0.090516264	0.298445703	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06821|0|hsa:23654|PLXNB2, MM1, Nbla00445, PLEXB2, dJ402G11.3; plexin B2; K06821 plexin B (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; IPT/TIG domain;; Sema domain;; Plexin repeat	Plexin-B2 (Precursor) GN=PLXNB2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: plexin-B2 [Odobenus rosmarus divergens]
ENSG00000196581(AJAP1)	--	0	0	0.024453806	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	AJAP1/PANP C-terminus	Adherens junction-associated protein 1 GN=AJAP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: adherens junction-associated protein 1-like [Tupaia chinensis]
ENSG00000196584(XRCC2)	--	10.065311	1089	10.06077	1024	11.243579	1212	8.44202	962	7.423702	875	7.145786	760	0.955873406	-0.209412799	normal	0.938703724	-0.247890832	normal	0.010792564	-0.680527538	normal	0.021879212	-0.378134597	normal	[L]	"Replication, recombination and repair"	--	K10879|0|hsa:7516|XRCC2; X-ray repair complementing defective repair in Chinese hamster cells 2; K10879 DNA-repair protein XRCC2 (A)	Homologous recombination (ko03440)	[L]	"Replication, recombination and repair"	Rad51	DNA repair protein XRCC2 GN=XRCC2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair protein XRCC2 [Orcinus orca]
ENSG00000196586(MYO6)	--	8.910516195	965	9.9551734	1020	8.247371815	930	10.28015979	1066	10.17252075	1176	9.265753001	1081	0.974516213	0.11260371	normal	0.964099204	0.183638617	normal	0.95595398	0.208457776	normal	0.411645173	0.167766285	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10358|0|hsa:4646|MYO6, DFNA22, DFNB37; myosin VI; K10358 myosin VI (A)"	--	[Z]	Cytoskeleton	Myosin head (motor domain)	Unconventional myosin-VI GN=MYO6 OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: unconventional myosin-VI isoform X1 [Ochotona princeps]
ENSG00000196588(MKL1)	--	13.73626	1204	18.473176	1618	15.592485	1434	21.85066588	1921	24.6187161	2125	24.11772334	2154	0.022176442	0.642535369	normal	0.833078725	0.371520841	normal	0.092654279	0.578180941	normal	0.000311332	0.521918772	normal	--	--	--	--	--	--	--	RPEL repeat;; SAP domain	MKL/myocardin-like protein 1 GN=MKL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: MKL/myocardin-like protein 1 [Myotis brandtii]
ENSG00000196591(HDAC2)	--	45.67899555	2167	44.92590824	2048	52.7725112	2235	43.99831809	2050	45.19689493	2052	40.932438	1867	0.983905663	-0.110826701	normal	0.986675483	-0.018597823	normal	0.948559082	-0.267645917	normal	0.519151941	-0.133134393	normal	[BQ]	"Chromatin structure and dynamics;; Secondary metabolites biosynthesis, transport and catabolism"	--	K06067|0|cjc:100402327|HDAC2; histone deacetylase 2; K06067 histone deacetylase 1/2 [EC:3.5.1.98] (A)	Cell cycle (ko04110);; Notch signaling pathway (ko04330);; Thyroid hormone signaling pathway (ko04919);; Huntington's disease (ko05016);; Alcoholism (ko05034);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Viral carcinogenesis (ko05203);; Chronic myeloid leukemia (ko05220)	[B]	Chromatin structure and dynamics	Histone deacetylase domain	Histone deacetylase 2 GN=HDAC2 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone deacetylase 2-like [Pantholops hodgsonii]
ENSG00000196604(POTEF)	--	0.27088492	24	0.184808993	16	0.3320195	29	0	0	0.022687172	1	0.023172924	2	0.000264897	-4.069429567	down	--	--	--	0.000705231	-3.125209131	down	--	--	--	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K17299|0|hsa:728378|POTEF, A26C1B, ACTB, POTE2alpha, POTEACTIN; POTE ankyrin domain family, member F; K17299 POTE ankyrin domain family protein (A)"	--	[Z]	Cytoskeleton	Actin;; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; CCDC144C protein coiled-coil region	POTE ankyrin domain family member F GN=POTEF OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	"Actin, cytoplasmic 1 [Myotis brandtii]"
ENSG00000196605(ZNF846)	--	1.602058151	27	2.11895758	42	0.565457174	20	1.143405394	16	0.37730912	12	0.51006439	12	0.958560743	-0.73110019	normal	0.033674032	-1.707006404	normal	0.977463343	-0.678425031	normal	0.063779812	-1.176962045	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:162993|ZNF846; zinc finger protein 846; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; C2H2-type zinc finger;; XPA protein N-terminal;; Zinc ribbon domain;; Probable zinc-binding domain;; Imidazoleglycerol-phosphate dehydratase"	Zinc finger protein 846 GN=ZNF846 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 846 [Leptonychotes weddellii]
ENSG00000196611(MMP1)	--	0	0	0.138834	5	0.0552468	1	0.0551774	2	0.0269825	0	0.0825973	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	K01388|0|ptr:451510|MMP1; matrix metallopeptidase 1 (interstitial collagenase); K01388 matrix metalloproteinase-1 (interstitial collagenase) [EC:3.4.24.7] (A)	PPAR signaling pathway (ko03320);; Pathways in cancer (ko05200);; Bladder cancer (ko05219);; Rheumatoid arthritis (ko05323)	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	27 kDa interstitial collagenase (Precursor) GN=MMP1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: interstitial collagenase [Galeopterus variegatus]
ENSG00000196620(UGT2B15)	--	0	0	0.0302743	1	0	0	0.0301461	1	0.146938	4	0.0602289	2	--	--	--	--	--	--	--	--	--	--	--	--	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00699|0|hsa:7366|UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8; UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17); K00699 glucuronosyltransferase [EC:2.4.1.17] (A)"	Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Steroid hormone biosynthesis (ko00140);; Starch and sucrose metabolism (ko00500);; Retinol metabolism (ko00830);; Porphyrin and chlorophyll metabolism (ko00860);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain	UDP-glucuronosyltransferase 2B15 (Precursor) GN=UGT2B15 OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronosyltransferase 2B31-like isoform X1 [Myotis lucifugus]
ENSG00000196628(TCF4)	--	2.851711506	217	3.106776465	208	6.169522097	207	6.847837763	348	7.458021988	426	4.682729447	238	0.11248167	0.646912791	normal	5.26E-05	1.007619688	up	0.949602369	0.191732069	normal	0.08729992	0.65719014	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K15603|0|mcf:102146624|TCF4; transcription factor 4; K15603 transcription factor 4/12 (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Transcription factor 4 GN=TCF4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	"Transcription factor 4, partial [Bos mutus]"
ENSG00000196632(WNK3)	--	0.207089814	18	0.025831959	5	0.00860823	0	0.030760162	6	0.058864527	11	0.025506572	5	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08867|0|ptr:465653|WNK3; WNK lysine deficient protein kinase 3; K08867 WNK lysine deficient protein kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Oxidative-stress-responsive kinase 1 C terminal	Serine/threonine-protein kinase WNK3 GN=WNK3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase WNK3 isoform 1 [Ceratotherium simum simum]
ENSG00000196636(SDHAF3)	--	23.61599917	339	24.126726	361	25.22203822	356	17.684076	294	20.53247	312	17.014299	260	0.93379833	-0.235155698	normal	0.934508394	-0.230838097	normal	0.631142687	-0.459364022	normal	0.231874146	-0.307637662	normal	--	--	--	--	--	[S]	Function unknown	Complex1_LYR-like	"Succinate dehydrogenase assembly factor 3, mitochondrial {ECO:0000250|UniProtKB:Q04401} (Precursor) OS=Homo sapiens (Human) PE=2 SV=1"	S	Function unknown	"PREDICTED: succinate dehydrogenase assembly factor 3, mitochondrial [Loxodonta africana]"
ENSG00000196639(HRH1)	--	2.783681168	211	1.722535127	144	1.94045749	145	3.776997576	292	3.08609356	241	2.924609327	230	0.731201756	0.435189193	normal	0.099880563	0.715668443	normal	0.221415593	0.651845529	normal	0.026407531	0.587521607	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04149|0|hsa:3269|HRH1, H1-R, H1R, HH1R, hisH1; histamine receptor H1; K04149 histamine receptor H1 (A)"	Calcium signaling pathway (ko04020);; Neuroactive ligand-receptor interaction (ko04080);; Inflammatory mediator regulation of TRP channels (ko04750)	[T]	Signal transduction mechanisms	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Histamine H1 receptor GN=HRH1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: histamine H1 receptor [Ursus maritimus] 
ENSG00000196642(RABL6)	--	44.677106	2836	43.58757	2850	47.31326683	3143	45.69703	2964	44.3592213	2905	46.0026308	3003	0.989762512	0.03283825	normal	0.98962071	0.006146456	normal	0.989275924	-0.073992813	normal	0.966060173	-0.013966723	normal	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family	Rab-like protein 6 GN=RABL6 OS=Homo sapiens (Human) PE=1 SV=2	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: rab-like protein 6 [Pteropus alecto] 
ENSG00000196646(ZNF136)	--	1.09574	76	1.264339	87	0.839485786	56	0.668444311	46	0.51170767	35	0.91596936	63	0.680760258	-0.735868741	normal	0.006704096	-1.298295482	down	0.973336464	0.157618503	normal	0.198617048	-0.625823535	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7695|ZNF136, pHZ-20; zinc finger protein 136; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Transposase zinc-ribbon domain"	Zinc finger protein 136 GN=ZNF136 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 564-like isoform X2 [Galeopterus variegatus]
ENSG00000196652(ZKSCAN5)	--	5.745828563	546	5.873125597	553	5.320772209	506	5.714484614	556	5.737407576	554	7.087139403	693	0.972725569	-0.004635406	normal	0.971989881	-0.018768782	normal	0.584616697	0.444287405	normal	0.563509026	0.147131276	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:23660|ZKSCAN5, ZFP95, ZNF914, ZSCAN37; zinc finger with KRAB and SCAN domains 5; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box"	Zinc finger protein with KRAB and SCAN domains 5 GN=ZKSCAN5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein with KRAB and SCAN domains 5 isoform X1 [Equus caballus] 
ENSG00000196653(ZNF502)	--	1.897183976	115	1.471439161	83	1.620019153	94	1.870901129	105	1.196360782	73	1.163250782	69	0.963308542	-0.159840815	normal	0.963841534	-0.202700182	normal	0.902684215	-0.445948544	normal	0.613702275	-0.264086173	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; XPA protein N-terminal;; Transposase zinc-ribbon domain"	Zinc finger protein 502 GN=ZNF502 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 502 [Equus caballus]
ENSG00000196655(TRAPPC4)	--	17.97881902	427	19.55255004	407	22.42898902	504	20.69643238	462	19.33667634	419	15.4303664	373	0.967441183	0.082538966	normal	0.969002348	0.020420112	normal	0.627753205	-0.440995405	normal	0.702980715	-0.115015724	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: intracellular (GO:0005622);; Biological Process: transport (GO:0006810);; Biological Process: ER to Golgi vesicle-mediated transport (GO:0006888);; Cellular Component: TRAPP complex (GO:0030008);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Sybindin-like family;; Sedlin, N-terminal conserved region"	Trafficking protein particle complex subunit 4 GN=TRAPPC4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: trafficking protein particle complex subunit 4 isoform X2 [Mustela putorius furo] 
ENSG00000196659(TTC30B)	--	5.49969	360	4.75354	312	4.17506	271	2.88472	189	2.7052	176	2.60316	170	0.000274439	-0.954716428	normal	0.005855756	-0.841886701	normal	0.118673261	-0.676241223	normal	0.000225845	-0.839576775	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 30B GN=TTC30B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 30B [Ailuropoda melanoleuca] 
ENSG00000196660(SLC30A10)	--	0.12403	4	0.331586	11	0	0	0.0616069	2	0.0301261	0	0.0923382	3	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: cation transmembrane transporter activity (GO:0008324);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14697|0|hsa:55532|SLC30A10, HMDPC, ZNT10, ZNT8, ZRC1, ZnT-10; solute carrier family 30, member 10; K14697 solute carrier family 30 (zinc transporter), member 10 (A)"	--	[P]	Inorganic ion transport and metabolism	Cation efflux family	Zinc transporter 10 GN=SLC30A10 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter 10 [Orycteropus afer afer]
ENSG00000196663(TECPR2)	--	4.05202	638	4.64713	729	4.51827	719	4.9021	737	5.46395	807	4.97018	765	0.958239815	0.176879373	normal	0.968789337	0.124976818	normal	0.973341986	0.081011323	normal	0.605779567	0.12555571	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Propeller	Tectonin beta-propeller repeat-containing protein 2 GN=TECPR2 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: tectonin beta-propeller repeat-containing protein 2 [Ceratotherium simum simum]
ENSG00000196664(TLR7)	--	0	0	0.0231531	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	"K05404|0|hsa:51284|TLR7, TLR7-like; toll-like receptor 7; K05404 toll-like receptor 7 (A)"	Toll-like receptor signaling pathway (ko04620);; Measles (ko05162);; Influenza A (ko05164)	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; TIR domain;; Leucine rich repeats (6 copies);; Leucine rich repeat;; Leucine Rich repeat	Toll-like receptor 7 (Precursor) GN=TLR7 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: toll-like receptor 7 [Galeopterus variegatus]
ENSG00000196666(FAM180B)	--	0.0877631	2	0	0	0	0	0	0	0.0428871	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM180 family	Protein FAM180B GN=FAM180B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM180B [Pteropus alecto]
ENSG00000196670(ZFP62)	--	5.0012339	441	4.3142136	363	4.719797631	424	4.784876	367	5.642663	391	5.976982	480	0.897153995	-0.294703426	normal	0.965033713	0.085429534	normal	0.955102374	0.170108133	normal	0.985893701	-0.008550356	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 62 homolog GN=ZFP62 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: uncharacterized protein LOC101285465 [Orcinus orca]
ENSG00000196683(TOMM7)	--	96.95055302	865	124.947563	1020	109.8455347	984	120.8707241	1096	88.3452613	783	93.8389149	846	0.890812653	0.310153153	normal	0.721834955	-0.402228654	normal	0.947800463	-0.225917257	normal	0.758315786	-0.096376954	normal	--	--	Cellular Component: mitochondrial outer membrane translocase complex (GO:0005742);; Biological Process: protein import into mitochondrial matrix (GO:0030150);; 	"K17771|3.33464e-28|hsa:54543|TOMM7, TOM7; translocase of outer mitochondrial membrane 7 homolog (yeast); K17771 mitochondrial import receptor subunit TOM7 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	TOM7 family	Mitochondrial import receptor subunit TOM7 homolog GN=TOMM7 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import receptor subunit TOM7 homolog isoform 1 [Dasypus novemcinctus]
ENSG00000196689(TRPV1)	--	8.5376923	841	8.44867287	919	9.534392632	919	8.829290588	861	9.138243949	929	8.38178548	951	0.977662511	0.003069631	normal	0.978135649	-0.005803325	normal	0.978198003	0.041022675	normal	0.975714352	0.012196481	normal	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05222|0|hsa:7442|TRPV1, VR1; transient receptor potential cation channel, subfamily V, member 1; K05222 transient receptor potential cation channel subfamily V member 1 (A)"	Neuroactive ligand-receptor interaction (ko04080);; Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ion transport protein	Transient receptor potential cation channel subfamily V member 1 GN=TRPV1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: transient receptor potential cation channel subfamily V member 1 [Galeopterus variegatus]
ENSG00000196693(ZNF33B)	--	3.65158512	384	5.97039066	405	3.6485305	328	3.301351104	331	3.6371261	325	5.029469524	390	0.929383342	-0.244054361	normal	0.857995267	-0.337498758	normal	0.931263966	0.24046892	normal	0.720794817	-0.115796039	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7582|ZNF33B, KOX2, KOX31, ZNF11B; zinc finger protein 33B; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; TFIIH C1-like domain;; BolA-like protein;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 33B GN=ZNF33B OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 33B-like [Leptonychotes weddellii]
ENSG00000196700(ZNF512B)	--	7.286706	962	7.2035	976	7.002967	943	9.441022	1246	9.42114	1231	8.334474	1107	0.852508102	0.341882114	normal	0.894061924	0.313018447	normal	0.951354927	0.222704143	normal	0.0887683	0.293432052	normal	--	--	--	--	--	[R]	General function prediction only	"C2H2-type zinc finger;; Zinc finger, C2H2 type;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 512B GN=ZNF512B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 512B isoform X1 [Galeopterus variegatus]
ENSG00000196704(AMZ2)	--	97.49982785	2275	111.720368	2419	110.397015	2374	90.112379	2066	80.37578302	1928	99.93451905	2341	0.978178709	-0.169738196	normal	0.880879119	-0.348487654	normal	0.988143141	-0.02846818	normal	0.341852165	-0.178801362	normal	[R]	General function prediction only	Molecular Function: zinc ion binding (GO:0008270);; 	K06974|0|hsa:51321|AMZ2; archaelysin family metallopeptidase 2; K06974 archaemetzincin [EC:3.4.-.-] (A)	--	--	--	Peptidase family M54	Archaemetzincin-2 GN=AMZ2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: archaemetzincin-2 isoform X2 [Galeopterus variegatus]
ENSG00000196705(ZNF431)	--	2.084175813	243	3.139041758	303	2.771417663	264	3.045324908	287	3.21106189	346	2.70735231	302	0.944138746	0.208050715	normal	0.952396823	0.169236812	normal	0.94998303	0.184729123	normal	0.550000738	0.185982876	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:170959|ZNF431; zinc finger protein 431; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; C1-like domain;; BolA-like protein"	Zinc finger protein 431 GN=ZNF431 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000196711(ALKAL1)	--	0.342269416	5	0.533283	6	0.903538	10	0.543289418	8	0.790571	6	0.540353239	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor signaling protein tyrosine kinase activator activity (GO:0030298);; Molecular Function: receptor tyrosine kinase binding (GO:0030971);; 	--	--	--	--	FAM150 family	Protein FAM150A (Precursor) GN=FAM150A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM150A [Mustela putorius furo] 
ENSG00000196712(NF1)	--	21.91103913	3901	26.66627473	4518	25.18718117	4169	23.86209012	3759	25.06907927	4018	23.57435488	4132	0.990635762	-0.084293522	normal	0.984155688	-0.190565577	normal	0.992302453	-0.021144856	normal	0.653862976	-0.100933348	normal	--	--	Biological Process: regulation of GTPase activity (GO:0043087);; 	K08052|0|pps:100988101|NF1; neurofibromin 1; K08052 neurofibromin 1 (A)	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014)	[V]	Defense mechanisms	GTPase-activator protein for Ras-like GTPase;; Divergent CRAL/TRIO domain	Neurofibromin truncated GN=NF1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neurofibromin isoform 1 [Odobenus rosmarus divergens]
ENSG00000196715(VKORC1L1)	--	33.562502	2512	33.976578	2578	32.67796	2392	32.174633	2538	28.096008	2234	27.097651	2214	0.988845042	-0.015966943	normal	0.968072064	-0.227905873	normal	0.984235534	-0.119774877	normal	0.570896959	-0.120712783	normal	--	--	--	--	--	--	--	Vitamin K epoxide reductase family;; Vitamin K epoxide reductase family	Vitamin K epoxide reductase complex subunit 1-like protein 1 GN=VKORC1L1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: vitamin K epoxide reductase complex subunit 1-like protein 1 [Eptesicus fuscus]
ENSG00000196724(ZNF418)	--	1.552272754	83	1.083584661	67	1.261959195	78	0.927140685	65	1.19119885	84	1.332241481	90	0.938800246	-0.375624614	normal	0.952350018	0.298768357	normal	0.964613618	0.194643559	normal	0.959171359	0.047906167	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:147686|ZNF418; zinc finger protein 418; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box"	Zinc finger protein 418 GN=ZNF418 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 256-like [Equus przewalskii]
ENSG00000196730(DAPK1)	--	24.65445637	2979	27.13973682	3292	24.40345467	2958	21.96824858	2652	14.45160437	1735	29.90022434	3621	0.977459544	-0.198471039	normal	2.99E-06	-0.944846621	normal	0.954435918	0.283343544	normal	0.654852818	-0.225193903	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: signal transduction (GO:0007165);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08803|0|hsa:1612|DAPK1, DAPK; death-associated protein kinase 1 (EC:2.7.11.1); K08803 death-associated protein kinase [EC:2.7.11.1] (A)"	Pathways in cancer (ko05200);; Bladder cancer (ko05219)	--	--	Ankyrin repeats (3 copies);; Protein kinase domain;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Protein tyrosine kinase;; Death domain;; Lipopolysaccharide kinase (Kdo/WaaP) family;; RIO1 family	Death-associated protein kinase 1 GN=DAPK1 OS=Homo sapiens (Human) PE=1 SV=6	T	Signal transduction mechanisms	PREDICTED: death-associated protein kinase 1-like [Tupaia chinensis]
ENSG00000196734(LCE1B)	--	0	0	0	0	0	0	0	0	0.0638752	0	0.0645291	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Late cornified envelope	--	--	--	--
ENSG00000196739(COL27A1)	--	3.3343632	659	3.07652833	643	3.2025516	654	5.881355911	1220	5.41402487	1097	5.006149269	1051	1.00E-04	0.856209788	normal	0.00288773	0.747884564	normal	0.013959997	0.674866425	normal	3.22E-07	0.762337476	normal	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; 	"K06236|0|hsa:85301|COL27A1, STLS; collagen, type XXVII, alpha 1; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; Laminin G domain	Collagen alpha-1(XXVII) chain (Precursor) GN=COL27A1 OS=Homo sapiens (Human) PE=2 SV=1	W	Extracellular structures	PREDICTED: collagen alpha-1(XXVII) chain [Pteropus alecto]
ENSG00000196743(GM2A)	--	21.51742937	1524	20.09437483	1422	19.816522	1369	19.1208023	1349	16.694881	1199	17.28265298	1236	0.96345537	-0.206583269	normal	0.936453212	-0.267206457	normal	0.972675173	-0.155554214	normal	0.250144511	-0.211058215	normal	--	--	--	"K12383|8.66487e-118|hsa:2760|GM2A, GM2-AP, SAP-3; GM2 ganglioside activator; K12383 ganglioside GM2 activator (A)"	Lysosome (ko04142)	--	--	ML domain	Ganglioside GM2 activator isoform short (Precursor) GN=GM2A OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: ganglioside GM2 activator [Galeopterus variegatus]
ENSG00000196747(HIST1H2AI)	--	3.40238	15	3.69656	17	2.08112	9	2.49529	12	1.52303	6	2.80714	13	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|2.85276e-70|ssc:100624086|histone H2A type 2-C-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1 GN=HIST1H2AM OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-A-like [Sus scrofa] 
ENSG00000196748(CLPSL2)	--	1.408880375	3	0.893925	2	0	0	0.414846	1	0.454771	0	0.267281	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Colipase-like	Colipase-like protein 2 (Precursor) GN=CLPSL2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: colipase-like protein 2 [Loxodonta africana]
ENSG00000196754(S100A2)	--	4.507897917	33	2.103348533	21	3.728612239	33	5.237751385	73	4.979330756	66	3.84443298	49	0.149874428	1.079997096	normal	0.004189346	1.563970572	up	0.939818228	0.541538605	normal	0.023567906	1.089787038	normal	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A2 GN=S100A2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein S100-A2 [Galeopterus variegatus] 
ENSG00000196757(ZNF700)	--	0.2835197	17	0.152529019	9	0.218205064	13	0.3023851	19	0.2132227	12	0.400608301	24	--	--	--	--	--	--	0.958897735	0.806303632	normal	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:90592|ZNF700; zinc finger protein 700; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain"	Zinc finger protein 700 GN=ZNF700 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	Zinc finger protein 709 [Tupaia chinensis]
ENSG00000196767(POU3F4)	--	0	0	0	0	0	0	0.0168524	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09365|0|ptr:100615412|POU3F4; POU class 3 homeobox 4; K09365 POU domain transcription factor, class 3 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 3, transcription factor 4 GN=POU3F4 OS=Homo sapiens (Human) PE=1 SV=2"	K	Transcription	"PREDICTED: POU domain, class 3, transcription factor 4 [Galeopterus variegatus]"
ENSG00000196776(CD47)	--	38.89604489	1358	37.034078	1313	41.10142	1403	74.01513414	2644	62.47236367	2184	69.1507691	2289	3.79E-06	0.92963956	normal	0.0047668	0.712037041	normal	0.005396936	0.697316815	normal	1.01E-08	0.783218005	normal	--	--	--	"K06266|0|hsa:961|CD47, IAP, MER6, OA3; CD47 molecule; K06266 CD47 antigen (Rh-related antigen, integrin-associated signal transducer) (A)"	ECM-receptor interaction (ko04512)	--	--	CD47 immunoglobulin-like domain;; CD47 transmembrane region	Leukocyte surface antigen CD47 (Precursor) GN=CD47 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: leukocyte surface antigen CD47 isoform X4 [Oryctolagus cuniculus]
ENSG00000196781(TLE1)	--	42.54642688	2811	41.29031849	2836	38.46273252	2663	38.91372062	2545	41.45202582	2717	42.54205238	2881	0.980513147	-0.174149965	normal	0.987814433	-0.083224179	normal	0.987050758	0.105168357	normal	0.845227974	-0.050199309	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[B]	Chromatin structure and dynamics	"Groucho/TLE N-terminal Q-rich domain;; WD domain, G-beta repeat"	Transducin-like enhancer protein 1 GN=TLE1 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: transducin-like enhancer protein 1 isoform X1 [Eptesicus fuscus]
ENSG00000196782(MAML3)	--	5.60755041	862	5.426561	822	6.426886098	832	5.652622	853	6.702791	1021	5.08756271	704	0.976922898	-0.045892161	normal	0.909693668	0.290865058	normal	0.93363721	-0.248807291	normal	0.975525862	0.013535042	normal	--	--	Molecular Function: transcription coactivator activity (GO:0003713);; Biological Process: Notch signaling pathway (GO:0007219);; Cellular Component: nuclear speck (GO:0016607);; Biological Process: positive regulation of transcription from RNA polymerase II promoter (GO:0045944);; 	"K06061|0|hsa:55534|MAML3, CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3; mastermind-like 3 (Drosophila); K06061 mastermind (A)"	Notch signaling pathway (ko04330)	--	--	MamL-1 domain	Mastermind-like protein 3 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	PREDICTED: mastermind-like protein 3 [Ceratotherium simum simum]
ENSG00000196787(HIST1H2AG)	--	1.852512	75	3.128968	116	2.895193	112	1.553975	63	1.369149	61	2.24809	93	0.960917584	-0.276188456	normal	0.076755239	-0.931629424	normal	0.948192848	-0.272444537	normal	0.246727622	-0.501450304	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|2.85276e-70|ssc:100624086|histone H2A type 2-C-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1 GN=HIST1H2AM OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-A-like [Sus scrofa] 
ENSG00000196792(STRN3)	--	15.6539613	944	15.60229421	989	15.485649	958	14.5495672	784	14.504737	870	12.828523	802	0.899684386	-0.298231906	normal	0.955012345	-0.206045478	normal	0.927336938	-0.264258301	normal	0.168962622	-0.256354214	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17608|0|hsa:29966|STRN3, SG2NA; striatin, calmodulin binding protein 3; K17608 striatin 1/3/4 (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Striatin family;; WD domain, G-beta repeat"	Striatin-3 GN=STRN3 OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	"PREDICTED: LOW QUALITY PROTEIN: striatin, calmodulin binding protein 3 [Tupaia chinensis]"
ENSG00000196793(ZNF239)	--	3.540494929	275	2.529721645	248	3.01003726	249	2.024886637	168	1.909647795	149	3.218352548	268	0.046801071	-0.73648098	normal	0.054732461	-0.750483572	normal	0.963230616	0.097226527	normal	0.239088943	-0.420023541	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; XPA protein N-terminal;; TFIIH C1-like domain;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 239 GN=ZNF239 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 239 [Galeopterus variegatus]
ENSG00000196811(CHRNG)	--	0.026025719	1	0.025409223	1	0.225058213	8	0	0	0.025327804	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04818|0|hsa:1146|CHRNG, ACHRG; cholinergic receptor, nicotinic, gamma (muscle); K04818 nicotinic acetylcholine receptor gamma (A)"	Neuroactive ligand-receptor interaction (ko04080)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Acetylcholine receptor subunit gamma (Precursor) GN=CHRNG OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: acetylcholine receptor subunit gamma isoform X1 [Camelus ferus]
ENSG00000196812(ZSCAN16)	--	3.464193	132	4.58333	178	4.574903	148	3.477147	134	4.524121	153	4.49218	167	0.968614933	-0.009032844	normal	0.941143447	-0.237592476	normal	0.957793829	0.164377432	normal	0.959389613	-0.033310802	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:80345|ZSCAN16, ZNF392, ZNF435, dJ265C24.3; zinc finger and SCAN domain containing 16; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger and SCAN domain-containing protein 16 GN=ZSCAN16 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 16 [Vicugna pacos]
ENSG00000196814(MVB12B)	--	4.427254496	414	4.742863999	426	4.59700687	434	3.883536486	364	4.40888982	415	3.439484289	318	0.940915824	-0.215670211	normal	0.967780628	-0.058956593	normal	0.606384594	-0.455099432	normal	0.351079854	-0.237216939	normal	--	--	Cellular Component: ESCRT I complex (GO:0000813);; 	"K12186|0|ptr:739730|MVB12B, FAM125B; multivesicular body subunit 12B; K12186 ESCRT-I complex subunit MVB12 (A)"	Endocytosis (ko04144)	[S]	Function unknown	Protein of unknown function (DUF2464)	Multivesicular body subunit 12B GN=MVB12B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: multivesicular body subunit 12B [Orcinus orca]
ENSG00000196821(C6orf106)	--	18.63495958	1605	18.62034584	1632	19.831371	1708	20.90532446	1801	22.62110859	1922	23.31061744	1998	0.979128866	0.135270336	normal	0.965585511	0.214357521	normal	0.965500633	0.217778715	normal	0.310606683	0.189527474	normal	--	--	--	--	--	[S]	Function unknown	UBA-like domain	Uncharacterized protein C6orf106 GN=C6orf106 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C6orf106 homolog isoform X1 [Elephantulus edwardii]
ENSG00000196826(CTD-2192J16.17)	--	1.393128689	77	1.833581614	101	1.413159986	77	1.391300262	78	1.272265	70	1.912041	106	0.973772202	-0.011979101	normal	0.815960924	-0.540575745	normal	0.888979211	0.445357911	normal	0.980210242	-0.026284302	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:468733|ZNF709; zinc finger protein 709; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 709 GN=ZNF709 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 709 [Galeopterus variegatus]
ENSG00000196834(POTEI)	--	0.257333191	39	0.171340369	26	0.195639074	29	0.019877923	3	0.04489575	6	0.013089695	2	1.22E-05	-3.184611757	down	0.216501641	-1.89143408	normal	0.000705231	-3.125209131	down	1.87E-06	-3.116812914	down	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K17299|0|hsa:653269|POTEI, POTE2beta; POTE ankyrin domain family, member I; K17299 POTE ankyrin domain family protein (A)"	--	[Z]	Cytoskeleton	Actin;; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; CCDC144C protein coiled-coil region	POTE ankyrin domain family member I GN=POTEI OS=Homo sapiens (Human) PE=3 SV=1	Z	Cytoskeleton	"PREDICTED: actin, cytoplasmic 1 [Camelus dromedarius]"
ENSG00000196839(ADA)	--	21.51111	628	17.56902	525	17.8284	552	19.77886	580	22.08437	655	12.788243	377	0.963053149	-0.145174196	normal	0.895946331	0.296983702	normal	0.217473291	-0.55653876	normal	0.830269031	-0.103134885	normal	[F]	Nucleotide transport and metabolism	Molecular Function: deaminase activity (GO:0019239);; 	K01488|0|hsa:100|ADA; adenosine deaminase (EC:3.5.4.4); K01488 adenosine deaminase [EC:3.5.4.4] (A)	Purine metabolism (ko00230);; Primary immunodeficiency (ko05340)	[F]	Nucleotide transport and metabolism	Adenosine/AMP deaminase	Adenosine deaminase GN=ADA OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: adenosine deaminase [Camelus ferus] 
ENSG00000196843(ARID5A)	--	2.400739991	115	2.100898195	101	2.548967362	121	2.593601155	119	3.130715984	148	1.936967466	92	0.969524098	0.018255687	normal	0.733822269	0.523307047	normal	0.900391238	-0.39787182	normal	0.910151281	0.069771227	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	ARID/BRIGHT DNA binding domain	AT-rich interactive domain-containing protein 5A GN=ARID5A OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 5A [Camelus bactrianus]
ENSG00000196844(PATE2)	--	0.132337301	3	0.254865604	2	0	0	0.043064986	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Prostate and testis expressed protein 2 (Precursor) GN=PATE2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: prostate and testis expressed protein 2 [Galeopterus variegatus]
ENSG00000196850(PPTC7)	--	12.339	891	11.2777	823	11.8598	850	13.3204	970	13.2082	953	13.0067	940	0.975282924	0.091575685	normal	0.958803657	0.18983284	normal	0.969909914	0.136675154	normal	0.538284782	0.137851783	normal	[T]	Signal transduction mechanisms	Molecular Function: catalytic activity (GO:0003824);; 	K17508|0|ptr:736888|PPTC7; PTC7 protein phosphatase homolog (S. cerevisiae) (EC:3.1.3.16); K17508 protein phosphatase 2C homolog 7 [EC:3.1.3.16] (A)	--	[T]	Signal transduction mechanisms	Stage II sporulation protein E (SpoIIE);; Protein phosphatase 2C;; Protein phosphatase 2C	Protein phosphatase PTC7 homolog GN=PPTC7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase PTC7 homolog [Erinaceus europaeus]
ENSG00000196860(TOMM20L)	--	0	0	0.140257	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: mitochondrial outer membrane translocase complex (GO:0005742);; Biological Process: protein targeting (GO:0006605);; Biological Process: intracellular protein transport (GO:0006886);; 	"K17770|7.09787e-91|hsa:387990|TOMM20L, UNQ9438; translocase of outer mitochondrial membrane 20 homolog (yeast)-like; K17770 mitochondrial import receptor subunit TOM20 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	MAS20 protein import receptor	TOMM20-like protein 1 GN=TOMM20L OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: TOMM20-like protein 1 isoform X1 [Sus scrofa]
ENSG00000196862(RGPD4)	--	0.00927782	1	0	0	0.00927021	0	0.0184324	2	0	0	0.0184566	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein targeting to Golgi (GO:0000042);; Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular transport (GO:0046907);; 	"K12172|0|hsa:285190|RGPD4, RGP4; RANBP2-like and GRIP domain containing 4; K12172 E3 SUMO-protein ligase RanBP2 (A)"	RNA transport (ko03013)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	RanBP1 domain;; GRIP domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	RanBP2-like and GRIP domain-containing protein 4 GN=RGPD4 OS=Homo sapiens (Human) PE=2 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: E3 SUMO-protein ligase RanBP2 [Ceratotherium simum simum]
ENSG00000196865(NHLRC2)	--	7.045758412	1118	8.429062023	1324	7.6225858	1173	6.481918708	1034	6.378616803	1012	6.874727738	1093	0.971555162	-0.143311395	normal	0.711415114	-0.408584813	normal	0.97633578	-0.110054032	normal	0.222832775	-0.224834562	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	NHL repeat;; Thioredoxin-like;; SMP-30/Gluconolaconase/LRE-like region;; Arylesterase	NHL repeat-containing protein 2 GN=NHLRC2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NHL repeat-containing protein 2 [Ceratotherium simum simum]
ENSG00000196866(HIST1H2AD)	--	0.283798	4	0	0	0.134627	1	0.9760904	4	0	0	0.693282	2	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|2.25872e-70|ngi:103749476|histone H2A type 1-D-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1-D GN=HIST1H2AD OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 1-D-like [Sarcophilus harrisii] 
ENSG00000196867(ZFP28)	--	5.247825519	422	5.064914541	428	4.819592184	408	3.152405	276	2.847288917	228	3.261555287	266	0.085125495	-0.640499821	normal	0.000326225	-0.925446252	normal	0.120715985	-0.622554275	normal	0.000356596	-0.729664135	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:140612|ZFP28, mkr5; ZFP28 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 28 homolog GN=ZFP28 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 28 homolog isoform X2 [Canis lupus familiaris]
ENSG00000196872(KIAA1211L)	--	0.389947519	23	0.695881903	39	0.443095081	35	0.151585366	14	0.497028898	21	0.230094777	17	0.971893751	-0.687611521	normal	0.851346577	-0.867953922	normal	0.827204673	-0.987679934	normal	0.149619029	-0.919853553	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4592)	Uncharacterized protein KIAA1211-like GN=KIAA1211L OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein KIAA1211-like homolog [Orycteropus afer afer]
ENSG00000196873(CBWD3)	--	2.180400564	45	2.75368095	65	2.130384233	46	2.216591172	49	3.047001965	70	1.868794365	49	0.979198615	0.089108495	normal	0.972856215	0.08361384	normal	0.978824767	0.08029834	normal	0.923805752	0.085526847	normal	[R]	General function prediction only	--	--	--	[H]	Coenzyme transport and metabolism	"CobW/HypB/UreG, nucleotide-binding domain;; Cobalamin synthesis protein cobW C-terminal domain;; Elongation factor Tu GTP binding domain"	COBW domain-containing protein 3 GN=CBWD3 OS=Homo sapiens (Human) PE=2 SV=1	H	Coenzyme transport and metabolism	PREDICTED: COBW domain-containing protein 2 isoform X4 [Canis lupus familiaris]
ENSG00000196876(SCN8A)	--	2.41461191	446	2.290647926	407	2.106019347	401	2.179546	413	1.790359991	357	1.829274469	316	0.960125919	-0.14122842	normal	0.942254012	-0.209698614	normal	0.841826973	-0.35047652	normal	0.374552614	-0.229616699	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: voltage-gated sodium channel complex (GO:0001518);; Molecular Function: ion channel activity (GO:0005216);; Molecular Function: voltage-gated sodium channel activity (GO:0005248);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K04840|0|mcc:695972|SCN8A; sodium channel, voltage gated, type VIII, alpha subunit; K04840 voltage-gated sodium channel type VIII alpha (A)"	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Domain of unknown function (DUF3451);; Sodium ion transport-associated;; Polycystin cation channel;; IQ calmodulin-binding motif	Sodium channel protein type 8 subunit alpha GN=SCN8A OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium channel protein type 8 subunit alpha isoform X3 [Bos taurus]
ENSG00000196878(LAMB3)	--	5.627845573	422	4.9620504	389	4.58999996	331	12.20535883	953	12.40473564	820	12.24667477	859	1.87E-08	1.141562573	up	1.04E-06	1.051548856	up	8.14E-12	1.363522835	up	4.26E-14	1.182704046	up	--	--	--	"K06244|0|hsa:3914|LAMB3, BM600-125KDA, LAM5, LAMNB1; laminin, beta 3; K06244 laminin, beta 3 (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Toxoplasmosis (ko05145);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Laminin EGF-like (Domains III and V);; Laminin N-terminal (Domain VI)	Laminin subunit beta-3 (Precursor) GN=LAMB3 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: laminin subunit beta-3 [Galeopterus variegatus]
ENSG00000196890(HIST3H2BB)	--	0.6472656	23	0.376295002	17	0.396816864	13	0.217623411	7	0.319968	12	0.489121	21	0.677946612	-1.550309742	normal	--	--	--	0.978443725	0.62585678	normal	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|9.08844e-63|umr:103678853|histone H2B type 3-B-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 3-B GN=HIST3H2BB OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2B type 3-B-like [Canis lupus familiaris] 
ENSG00000196911(KPNA5)	--	1.323070291	139	1.263204681	147	1.098048334	154	1.286960423	157	1.481864995	164	1.348625948	153	0.9610849	0.143355859	normal	0.959986106	0.135136442	normal	0.967632538	-0.017517555	normal	0.872150716	0.086272738	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: protein import into nucleus (GO:0006606);; Molecular Function: protein transporter activity (GO:0008565);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Armadillo/beta-catenin-like repeat;; Importin beta binding domain;; HEAT repeats;; HEAT-like repeat;; HEAT repeat;; Rapamycin-insensitive companion of mTOR, domain 5;; Armadillo-like;; V-ATPase subunit H"	Importin subunit alpha-6 GN=KPNA5 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin subunit alpha-6 [Panthera tigris altaica]
ENSG00000196912(ANKRD36B)	--	1.28800281	174	1.375277527	184	1.10992996	147	0.85324612	115	0.758388884	102	0.86633628	117	0.427283685	-0.621483335	normal	0.028986034	-0.862895413	normal	0.916930732	-0.333741976	normal	0.055003858	-0.617980178	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 36B GN=ANKRD36B OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like [Physeter catodon]
ENSG00000196914(ARHGEF12)	--	17.15798725	3175	16.1367226	3010	17.12518376	3179	18.59722889	3454	19.07500788	3511	19.89531457	3670	0.989295308	0.09063717	normal	0.979190028	0.200598561	normal	0.980274075	0.198827505	normal	0.405707609	0.16267832	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	K07532|0|pps:100981550|ARHGEF12; Rho guanine nucleotide exchange factor (GEF) 12; K07532 Rho guanine nucleotide exchange factor 12 (A)	Vascular smooth muscle contraction (ko04270);; Axon guidance (ko04360);; Platelet activation (ko04611);; Regulation of actin cytoskeleton (ko04810);; Tuberculosis (ko05152);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Regulator of G protein signalling-like domain;; RhoGEF domain;; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Rho guanine nucleotide exchange factor 12 GN=ARHGEF12 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 12 isoform X1 [Equus przewalskii]
ENSG00000196917(HCAR1)	--	0	0	0	0	0	0	0.0130865	1	0.0889376	6	0.0388874	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08401|0|hsa:27198|HCAR1, GPR104, GPR81, HCA1, LACR1, TA-GPCR, TAGPCR; hydroxycarboxylic acid receptor 1; K08401 G protein-coupled receptor 81 (A)"	cAMP signaling pathway (ko04024)	--	--	7 transmembrane receptor (rhodopsin family)	Hydroxycarboxylic acid receptor 1 GN=HCAR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: hydroxycarboxylic acid receptor 1 [Galeopterus variegatus]
ENSG00000196923(PDLIM7)	--	39.4733408	1175	25.7742246	748	34.69431436	1077	109.8486386	3078	111.8472801	3260	45.830315	1382	4.29E-14	1.357362724	up	0	2.10011705	up	0.842204949	0.351011746	normal	0.037363419	1.340934398	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain;; PDZ domain (Also known as DHR or GLGF)	PDZ and LIM domain protein 7 GN=PDLIM7 OS=Homo sapiens (Human) PE=1 SV=1	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: PDZ and LIM domain protein 7 isoform X2 [Physeter catodon]
ENSG00000196924(FLNA)	--	291.1348102	56648	309.76541	61398	317.564812	63263	518.55764	100964	477.450617	92617	398.804215	78005	0.00166853	0.802895261	normal	0.615250594	0.571647269	normal	0.995384462	0.29390685	normal	0.005927648	0.561125173	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K04437|0|hsa:2316|FLNA, ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD; filamin A, alpha; K04437 filamin (A)"	MAPK signaling pathway (ko04010);; Focal adhesion (ko04510);; Salmonella infection (ko05132);; Proteoglycans in cancer (ko05205)	[Z]	Cytoskeleton	Filamin/ABP280 repeat;; Calponin homology (CH) domain;; Y_Y_Y domain;; YtkA-like	Filamin-A GN=FLNA OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: filamin-A isoform X1 [Galeopterus variegatus]
ENSG00000196932(TMEM26)	--	0.2121821	6	0.128124325	10	0.1628864	8	0.165976	6	0.338659	8	0.128433646	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Transmembrane protein 26	Transmembrane protein 26 GN=TMEM26 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 26 [Lipotes vexillifer]
ENSG00000196935(SRGAP1)	--	6.7060469	1228	8.742686259	1571	8.209045545	1492	10.1202105	1830	8.645530341	1584	13.9541984	2495	0.17329193	0.544139829	normal	0.984161189	-0.009528269	normal	0.001999552	0.732920167	normal	0.224879061	0.441366094	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	K07526|0|mcf:102141156|SRGAP1; SLIT-ROBO Rho GTPase activating protein 1; K07526 SLIT-ROBO Rho GTPase activating protein (A)	Axon guidance (ko04360)	[Z]	Cytoskeleton	"RhoGAP domain;; Fes/CIP4, and EFC/F-BAR homology domain;; Variant SH3 domain;; SH3 domain;; Variant SH3 domain"	SLIT-ROBO Rho GTPase-activating protein 1 GN=SRGAP1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: SLIT-ROBO Rho GTPase-activating protein 1 [Ailuropoda melanoleuca] 
ENSG00000196937(FAM3C)	--	36.867187	1406	32.400472	1244	33.088303	1286	38.27902557	1447	40.72602216	1375	35.41757019	1302	0.983479441	0.01062462	normal	0.976565174	0.122876453	normal	0.982479648	0.009536219	normal	0.866242856	0.04578011	normal	--	--	--	--	--	--	--	--	Protein FAM3C (Precursor) GN=FAM3C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM3C [Canis lupus familiaris] 
ENSG00000196943(NOP9)	--	23.82654373	2107	22.39687524	2199	20.94668746	2133	18.18196195	2069	20.83222961	2283	23.11031886	2371	0.986430009	-0.057046952	normal	0.987308406	0.032634671	normal	0.981812095	0.144223229	normal	0.880106821	0.041483954	normal	--	--	--	K14790|0|pps:100979193|NOP9; NOP9 nucleolar protein; K14790 nucleolar protein 9 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Pumilio-family RNA binding repeat	Nucleolar protein 9 GN=NOP9 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: nucleolar protein 9 [Galeopterus variegatus]
ENSG00000196946(ZNF705A)	--	2.472714404	89	2.041483481	115	2.53555542	86	2.420538738	68	3.636972036	98	3.024674663	95	0.922870542	-0.410959222	normal	0.949942328	-0.248660225	normal	0.968045253	0.133072192	normal	0.763585599	-0.172498001	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:440077|ZNF705A; zinc finger protein 705A; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; KRAB box;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 705A GN=ZNF705A OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 596-like [Lipotes vexillifer]
ENSG00000196950(SLC39A10)	--	25.93151572	2149	22.16006688	1823	24.31653101	1947	25.91332754	2142	26.82029704	2102	30.14804316	2433	0.987199936	-0.035513834	normal	0.974147402	0.183879402	normal	0.919023791	0.312974104	normal	0.439378065	0.153019296	normal	[P]	Inorganic ion transport and metabolism	Cellular Component: membrane (GO:0016020);; Biological Process: metal ion transport (GO:0030001);; Molecular Function: metal ion transmembrane transporter activity (GO:0046873);; Biological Process: transmembrane transport (GO:0055085);; 	"K14716|0|hsa:57181|SLC39A10, LZT-Hs2; solute carrier family 39 (zinc transporter), member 10; K14716 solute carrier family 39 (zinc transporter), member 10 (A)"	--	[P]	Inorganic ion transport and metabolism	ZIP Zinc transporter	Zinc transporter ZIP10 (Precursor) GN=SLC39A10 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: zinc transporter ZIP10 [Panthera tigris altaica] 
ENSG00000196954(CASP4)	--	3.118345174	98	3.509692677	132	3.567252309	114	7.565836546	232	7.57491439	258	9.95540665	315	2.36E-05	1.199857788	up	0.00230147	0.937587535	normal	4.19E-09	1.445997817	up	1.07E-06	1.206233896	up	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K04394|0|hsa:837|CASP4, ICE(rel)II, ICEREL-II, ICH-2, Mih1/TX, TX; caspase 4, apoptosis-related cysteine peptidase (EC:3.4.22.57); K04394 caspase 4 [EC:3.4.22.57] (A)"	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase domain;; Caspase recruitment domain	Caspase-4 subunit 2 (Precursor) GN=CASP4 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-13-like [Pteropus alecto]
ENSG00000196961(AP2A1)	--	53.69922026	3576	41.64528021	2781	51.47434954	3488	50.38450614	3337	54.050673	3592	49.05771327	3288	0.98759893	-0.130569222	normal	0.903662945	0.347590334	normal	0.989349164	-0.09343945	normal	0.9074175	0.03254049	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Biological Process: vesicle-mediated transport (GO:0016192);; Cellular Component: membrane coat (GO:0030117);; Cellular Component: clathrin adaptor complex (GO:0030131);; 	"K11824|0|pps:100990247|AP2A1; adaptor-related protein complex 2, alpha 1 subunit; K11824 AP-2 complex subunit alpha (A)"	Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Huntington's disease (ko05016)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Adaptin N terminal region;; Alpha adaptin AP2, C-terminal domain;; Adaptin C-terminal domain;; non-SMC mitotic condensation complex subunit 1"	AP-2 complex subunit alpha-1 GN=AP2A1 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-2 complex subunit alpha-1 isoform X5 [Mustela putorius furo] 
ENSG00000196967(ZNF585A)	--	11.58282414	426	11.03264484	403	12.68235956	449	11.28307615	471	10.39981409	455	14.84375908	539	0.964415203	0.113651447	normal	0.957297599	0.153119148	normal	0.924763447	0.254495033	normal	0.503126917	0.176359005	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:199704|ZNF585A; zinc finger protein 585A; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; TFIIH C1-like domain"	Zinc finger protein 585A GN=ZNF585A OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 585A [Ceratotherium simum simum]
ENSG00000196968(FUT11)	--	10.18688411	676	11.59036602	870	11.49395419	778	8.423372	640	8.595397299	557	9.306259499	687	0.969131615	-0.109527707	normal	0.024884093	-0.663310942	normal	0.956704389	-0.187363656	normal	0.087201226	-0.323892415	normal	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: fucosyltransferase activity (GO:0008417);; Cellular Component: membrane (GO:0016020);; 	"K11257|0|pps:100980383|FUT11; fucosyltransferase 11 (alpha (1,3) fucosyltransferase); K11257 galactoside 3-L-fucosyltransferase 11 [EC:2.4.1.-] (A)"	--	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	Glycosyltransferase family 10 (fucosyltransferase)	"Alpha-(1,3)-fucosyltransferase 11 GN=FUT11 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: alpha-(1,3)-fucosyltransferase 11 [Odobenus rosmarus divergens]"
ENSG00000196972(SMIM10L2B)	--	0.241843	14	0.150469	9	0.264644	15	0.0864517	5	0.219796	12	0.290683	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4560)	Small integral membrane protein 10 GN=SMIM10 OS=Homo sapiens (Human) PE=4 SV=4	S	Function unknown	PREDICTED: uncharacterized protein MGC39606-like [Sorex araneus]
ENSG00000196975(ANXA4)	--	85.03202682	3585	97.53824914	4084	89.8035311	3714	151.9252644	6437	151.453181	6325	203.250025	8739	0.000182978	0.813319506	normal	0.078901053	0.60947336	normal	8.95E-12	1.225867661	up	0.000444169	0.89714736	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	"K17093|0|hsa:307|ANXA4, ANX4, HEL-S-274, PIG28, ZAP36; annexin A4; K17093 annexin A4 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A4 GN=ANXA4 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	annexin A4 [Sus scrofa] 
ENSG00000196976(LAGE3)	--	44.2922	618	42.3426	631	38.4147	575	38.8329	557	41.8559	585	40.9088	584	0.955270936	-0.180289349	normal	0.964946	-0.130305493	normal	0.973295923	0.014078231	normal	0.714727918	-0.100852085	normal	--	--	--	"K15902|5.35601e-55|hsa:8270|LAGE3, CVG5, DXS9879E, DXS9951E, ESO3, ITBA2; L antigen family, member 3; K15902 EKC/KEOPS complex subunit PCC1/LAGE3 (A)"	--	--	--	Transcription factor Pcc1	EKC/KEOPS complex subunit LAGE3 GN=LAGE3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	"PREDICTED: L antigen family member 3, partial [Ovis aries]"
ENSG00000196981(WDR5B)	--	4.0958	223	4.69337	256	4.98208	267	4.46224	245	4.20181	228	4.56804	249	0.962492692	0.10422058	normal	0.94870698	-0.187362932	normal	0.962176468	-0.108349807	normal	0.875438133	-0.068179801	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14963|0|hsa:54554|WDR5B; WD repeat domain 5B; K14963 COMPASS component SWD3 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A;; Nucleoporin Nup120/160"	WD repeat-containing protein 5B GN=WDR5B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: WD repeat-containing protein 5B [Camelus dromedarius]
ENSG00000196993(NPIPB9)	--	0.090994317	3	0.0880891	3	0.181118352	5	0.181197461	6	0.2233337	7	0.059915479	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B9 GN=NPIPB9 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	--
ENSG00000196998(WDR45)	--	49.64511106	1157	49.29954166	1155	49.09944736	1182	46.44696729	1118	51.10235688	1226	52.85803568	1280	0.978655316	-0.080192596	normal	0.979641217	0.064557521	normal	0.977743706	0.106491375	normal	0.911866656	0.031979918	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"WD domain, G-beta repeat;; CNH domain;; CPSF A subunit region"	WD repeat domain phosphoinositide-interacting protein 4 GN=WDR45 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	WD repeat domain phosphoinositide-interacting protein 4 [Bos mutus]
ENSG00000197006(METTL9)	--	56.54170952	2065	46.8474915	1840	55.34615757	2047	53.59396443	1953	54.14024023	2005	51.68999127	1868	0.983337135	-0.111197003	normal	0.983114181	0.102389281	normal	0.980472292	-0.140199621	normal	0.839977961	-0.05205387	normal	--	--	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[S]	Function unknown	DREV methyltransferase;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain	Methyltransferase-like protein 9 (Precursor) GN=METTL9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: methyltransferase-like protein 9 isoform X1 [Leptonychotes weddellii]
ENSG00000197008(ZNF138)	--	3.286736718	116	3.472267279	123	2.36380516	99	2.952038709	126	2.456357812	119	2.83930132	110	0.967277674	0.087356344	normal	0.966621642	-0.068269872	normal	0.965418853	0.141657964	normal	0.945293294	0.04886359	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|9.94916e-167|pon:100433721|ZNF85; zinc finger protein 85; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; KRAB box;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; C1-like domain"	Zinc finger protein 138 GN=ZNF138 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	hypothetical protein PANDA_021666 [Ailuropoda melanoleuca]
ENSG00000197013(ZNF429)	--	0.0243889	1	0.074110516	3	0.073563931	2	0.029292897	1	0.0709258	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:353088|ZNF429; zinc finger protein 429; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; C1-like domain;; SprT-like family"	Zinc finger protein 429 GN=ZNF429 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 420-like isoform X2 [Myotis brandtii]
ENSG00000197016(ZNF470)	--	1.386046751	166	1.721077282	219	1.867437281	203	1.551250444	204	1.059252814	129	1.83528317	218	0.931634855	0.264343562	normal	0.052916461	-0.77790235	normal	0.963521257	0.093881948	normal	0.821021955	-0.114898583	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:388566|ZNF470, CZF-1; zinc finger protein 470; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 470 GN=ZNF470 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 470-like [Leptonychotes weddellii]
ENSG00000197019(SERTAD1)	--	12.18765814	431	13.05240361	471	11.62349087	418	14.61160402	519	12.4202844	436	12.31683451	437	0.933399701	0.236445458	normal	0.961300997	-0.13238355	normal	0.968971448	0.055642001	normal	0.874698386	0.054698265	normal	--	--	--	--	--	--	--	SERTA motif	SERTA domain-containing protein 1 GN=SERTAD1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: SERTA domain-containing protein 1 [Dasypus novemcinctus]
ENSG00000197020(ZNF100)	--	0.10565779	9	0.110874373	4	0.110109504	8	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:163227|ZNF100; zinc finger protein 100; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; SprT-like family;; C1-like domain"	Zinc finger protein 100 GN=ZNF100 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000197021(CXorf40B)	--	15.12152062	409	12.78698879	354	14.62889218	409	16.66551092	463	17.30391634	469	16.20695583	436	0.959152498	0.14755789	normal	0.784723701	0.38298642	normal	0.967027379	0.08363629	normal	0.434571438	0.201906979	normal	--	--	--	--	--	--	--	--	Protein CXorf40B GN=CXorf40B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein CXorf40A homolog [Ursus maritimus] 
ENSG00000197024(ZNF398)	--	3.934915982	413	4.46744893	453	3.866021645	383	4.004037432	436	4.29022009	477	4.711937315	513	0.969193694	0.047183249	normal	0.969051046	0.052879619	normal	0.70926729	0.411912877	normal	0.524994101	0.170278366	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100969653|ZNF398; zinc finger protein 398; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc finger protein;; C2H2-type zinc finger"	Zinc finger protein 398 GN=ZNF398 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 398 [Oryctolagus cuniculus]
ENSG00000197037(ZSCAN25)	--	4.929297636	340	4.337502458	324	5.5199125	362	6.020539581	399	5.632167	392	5.30383047	393	0.946123938	0.199190185	normal	0.924903333	0.252361064	normal	0.963606235	0.1098078	normal	0.51196042	0.185569096	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:221785|ZSCAN25, ZNF498; zinc finger and SCAN domain containing 25; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger and SCAN domain-containing protein 25 GN=ZSCAN25 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger and SCAN domain-containing protein 25 [Equus caballus]
ENSG00000197043(ANXA6)	--	25.45811835	1426	21.23504664	1223	22.62987933	1299	21.17558	1191	28.66011209	1602	16.60928218	932	0.919039408	-0.290290024	normal	0.823907046	0.367624934	normal	0.388126835	-0.486619018	normal	0.823658122	-0.1054892	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	"K17094|0|hsa:309|ANXA6, ANX6, CBP68; annexin A6; K17094 annexin A6 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A6 GN=ANXA6 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A6 [Tupaia chinensis]
ENSG00000197044(ZNF441)	--	0	0	0	0	0.0113242	0	0.0669205	6	0.0653192	5	0.055669	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 441 GN=ZNF441 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 709-like [Balaenoptera acutorostrata scammoni]
ENSG00000197045(GMFB)	--	32.60340764	1778	39.615689	2143	36.36148367	1925	41.33213105	2278	38.41087097	2089	38.0677036	2076	0.901390412	0.326430426	normal	0.986188956	-0.058204312	normal	0.984016041	0.100580452	normal	0.575552504	0.118718468	normal	--	--	Molecular Function: actin binding (GO:0003779);; Cellular Component: intracellular (GO:0005622);; 	--	--	[W]	Extracellular structures	Cofilin/tropomyosin-type actin-binding protein	Glia maturation factor beta GN=GMFB OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: glia maturation factor beta [Capra hircus]
ENSG00000197050(ZNF420)	--	3.246231976	194	3.725536	222	3.689942	223	3.139919002	187	3.7790731	192	4.882224009	279	0.964511743	-0.083179592	normal	0.939373123	-0.229199317	normal	0.895440663	0.313028394	normal	0.974305101	0.022373651	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:147923|ZNF420, APAK; zinc finger protein 420; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; XPA protein N-terminal;; TFIIH C1-like domain;; Probable zinc-binding domain;; Rad4 beta-hairpin domain 1"	Zinc finger protein 420 GN=ZNF420 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: uncharacterized protein LOC101331200 [Tursiops truncatus]
ENSG00000197056(ZMYM1)	--	5.9058974	448	6.681735664	484	6.502044	486	5.9209197	463	5.272936	403	5.3325843	411	0.970707708	0.016625114	normal	0.904737749	-0.284677417	normal	0.927116266	-0.249264871	normal	0.516025214	-0.172636917	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	--	--	Domain of unknown function (DUF4371);; MYM-type Zinc finger with FCS sequence motif;; hAT family C-terminal dimerisation region	Zinc finger MYM-type protein 1 GN=ZMYM1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger MYM-type protein 1 isoform X1 [Equus przewalskii] 
ENSG00000197061(HIST1H4C)	--	59.2807	157	35.8408	99	42.783	120	55.7647	166	60.3485	159	79.8127	223	0.96677831	0.049118933	normal	0.405330376	0.654147418	normal	0.010671497	0.87748027	normal	0.138450342	0.52309804	normal	[B]	Chromatin structure and dynamics	--	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000197070(ARRDC1)	--	18.734504	491	13.78923612	387	17.442472	446	19.554777	512	17.83075188	470	18.621757	496	0.971376432	0.02949813	normal	0.921839516	0.257984642	normal	0.960540153	0.144540031	normal	0.620863652	0.137502839	normal	--	--	--	--	--	[R]	General function prediction only	"Arrestin (or S-antigen), N-terminal domain;; Arrestin (or S-antigen), C-terminal domain;; Vacuolar protein sorting-associated protein 26"	Arrestin domain-containing protein 1 GN=ARRDC1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: arrestin domain-containing protein 1 isoform X1 [Felis catus]
ENSG00000197077(KIAA1671)	--	5.311324103	1108	6.525491155	1215	6.617285	1204	6.986437687	1283	6.837236459	1231	5.314767871	1003	0.966484994	0.180498283	normal	0.981416035	-0.002548958	normal	0.928246616	-0.271431144	normal	0.93492335	-0.025927806	normal	--	--	--	--	--	--	--	Tankyrase binding protein C terminal domain	Uncharacterized protein KIAA1671 GN=KIAA1671 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein KIAA1671 homolog [Galeopterus variegatus]
ENSG00000197081(IGF2R)	--	32.91360168	6775	31.81981462	6592	32.76562762	6683	31.62516485	6676	31.09949191	6391	41.32171402	8458	0.994532826	-0.052057362	normal	0.993961931	-0.066085715	normal	0.95397871	0.331462425	normal	0.763208687	0.08190919	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06564|0|hsa:3482|IGF2R, CD222, CIMPR, M6P-R, MPR1, MPRI; insulin-like growth factor 2 receptor; K06564 insulin-like growth factor 2 receptor (A)"	Lysosome (ko04142)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Cation-independent mannose-6-phosphate receptor repeat;; Autophagy-related protein 27;; Fibronectin type II domain;; Mannose-6-phosphate receptor;; Glucosidase II beta subunit-like protein	Cation-independent mannose-6-phosphate receptor (Precursor) GN=IGF2R OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	cation-independent mannose-6-phosphate receptor precursor [Canis lupus familiaris] 
ENSG00000197093(GAL3ST4)	--	0.473642878	8	0.288765686	11	0.572681068	7	0.101908535	2	0.150993562	4	0.150174009	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: galactosylceramide sulfotransferase activity (GO:0001733);; Cellular Component: Golgi apparatus (GO:0005794);; Biological Process: glycolipid biosynthetic process (GO:0009247);; Cellular Component: integral component of membrane (GO:0016021);; 	"K09677|0|hsa:79690|GAL3ST4, GAL3ST-4; galactose-3-O-sulfotransferase 4; K09677 galactose-3-O-sulfotransferase 4 [EC:2.8.2.-] (A)"	--	--	--	Galactose-3-O-sulfotransferase	Galactose-3-O-sulfotransferase 4 GN=GAL3ST4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: galactose-3-O-sulfotransferase 4 [Ursus maritimus]
ENSG00000197102(DYNC1H1)	--	47.12157977	15601	52.08589118	17340	57.95690528	19201	54.50125882	18024	51.32699188	16889	52.25889357	17263	0.995279559	0.177432182	normal	0.997313001	-0.059441295	normal	0.996018627	-0.161776246	normal	0.956115095	-0.020139269	normal	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10413|0|nle:100601904|DYNC1H1; dynein, cytoplasmic 1, heavy chain 1; K10413 dynein heavy chain 1, cytosolic (A)"	Phagosome (ko04145);; Vasopressin-regulated water reabsorption (ko04962);; Salmonella infection (ko05132)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 1;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; P-loop containing dynein motor region D4;; ATP-binding dynein motor region D5;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; P-loop containing dynein motor region D3;; AAA domain;; ATPase family associated with various cellular activities (AAA);; AAA domain;; AAA ATPase domain;; AAA domain;; AAA domain;; Magnesium chelatase, subunit ChlI;; Part of AAA domain;; Type II/IV secretion system protein"	Cytoplasmic dynein 1 heavy chain 1 GN=DYNC1H1 OS=Homo sapiens (Human) PE=1 SV=5	Z	Cytoskeleton	PREDICTED: cytoplasmic dynein 1 heavy chain 1 [Ceratotherium simum simum]
ENSG00000197106(SLC6A17)	--	1.299154903	168	1.132884985	149	1.4025188	184	1.406957826	181	1.574108846	201	1.282122268	166	0.96526657	0.076026282	normal	0.833320735	0.406889256	normal	0.957935994	-0.155468041	normal	0.817401183	0.108301901	normal	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05048|0|hsa:388662|SLC6A17, NTT4; solute carrier family 6 (neutral amino acid transporter), member 17; K05048 solute carrier family 6 (neurotransmitter transporter, amino acid/orphan) member 15/16/17/18/20 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium-dependent neutral amino acid transporter SLC6A17 GN=SLC6A17 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent neutral amino acid transporter SLC6A17 [Trichechus manatus latirostris]
ENSG00000197111(PCBP2)	--	324.915188	8661	320.98163	8626	312.1378721	8260	376.3337123	9941	372.9383673	9881	401.5458938	10822	0.992808484	0.167997281	normal	0.992259319	0.17451018	normal	0.921150451	0.381400834	normal	0.209768697	0.241425572	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	K13162|0|umr:103675535|PCBP2; poly(rC) binding protein 2; K13162 poly(rC)-binding protein 2/3/4 (A)	--	[AR]	RNA processing and modification;; General function prediction only	KH domain;; KH domain;; KH domain;; KH domain	Poly(rC)-binding protein 2 GN=PCBP2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: poly(rC)-binding protein 2 isoform X10 [Myotis davidii]
ENSG00000197119(SLC25A29)	--	15.48176464	798	9.775521767	585	12.57942689	752	19.96949246	1068	21.75669289	1149	16.8623138	1002	0.74850227	0.388969432	normal	9.21E-06	0.950658297	normal	0.703026746	0.405078464	normal	0.000222894	0.571271837	normal	--	--	--	"K15109|3.91959e-176|hsa:123096|SLC25A29, C14orf69, CACL, ORNT3; solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29; K15109 solute carrier family 25 (mitochondrial carnitine/acylcarnitine transporter), member 20/29 (A)"	--	[C]	Energy production and conversion	Mitochondrial carrier protein	Mitochondrial basic amino acids transporter GN=SLC25A29 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: LOW QUALITY PROTEIN: mitochondrial carnitine/acylcarnitine carrier protein CACL [Pteropus alecto]
ENSG00000197121(PGAP1)	--	5.261674919	633	5.245113299	583	4.392873244	577	3.226948908	367	3.169579248	391	3.45589834	385	0.001059694	-0.814626343	normal	0.126549201	-0.595853097	normal	0.129053136	-0.590097706	normal	0.000187182	-0.670645976	normal	--	--	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	"K05294|0|hsa:80055|PGAP1, Bst1, ISPD3024, MRT42, SPG67; post-GPI attachment to proteins 1; K05294 glycosylphosphatidylinositol deacylase [EC:3.-.-.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	PGAP1-like protein	GPI inositol-deacylase GN=PGAP1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: GPI inositol-deacylase [Oryctolagus cuniculus]
ENSG00000197122(SRC)	--	50.42547546	4034	48.12542709	3949	47.89372107	3969	63.27408155	5096	66.22615973	5281	74.86700148	6047	0.952311207	0.30621797	normal	0.850001318	0.397765079	normal	0.081287986	0.598966349	normal	0.004460237	0.437867557	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K05704|0|ptr:458229|SRC; SRC proto-oncogene, non-receptor tyrosine kinase; K05704 tyrosine-protein kinase Src [EC:2.7.10.2] (A)"	ErbB signaling pathway (ko04012);; Rap1 signaling pathway (ko04015);; Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; VEGF signaling pathway (ko04370);; Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Gap junction (ko04540);; Platelet activation (ko04611);; GABAergic synapse (ko04727);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Prolactin signaling pathway (ko04917);; Thyroid hormone signaling pathway (ko04919);; Oxytocin signaling pathway (ko04921);; Bacterial invasion of epithelial cells (ko05100);; Tuberculosis (ko05152);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203);; Proteoglycans in cancer (ko05205)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Proto-oncogene tyrosine-protein kinase Src GN=SRC OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: neuronal proto-oncogene tyrosine-protein kinase Src-like isoform X2 [Mustela putorius furo] 
ENSG00000197134(ZNF257)	--	0.047743507	3	0.197455068	1	0	0	0.062763327	4	0.194036648	3	0.015700974	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:113835|ZNF257, BMZF-4, BMZF4; zinc finger protein 257; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain"	Zinc finger protein 257 GN=ZNF257 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000197136(PCNX3)	--	17.2585	2247	17.5022	2314	18.1867	2432	18.9526	2458	20.744	2688	20.5169	2686	0.985814119	0.098588063	normal	0.976153871	0.19459963	normal	0.984183136	0.134944759	normal	0.483683539	0.142683912	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Pecanex protein (C-terminus)	Pecanex-like protein 3 GN=PCNXL3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: pecanex-like protein 3 [Lipotes vexillifer]
ENSG00000197140(ADAM32)	--	0.392006915	15	0.139087594	5	0.434686419	18	0.329003603	12	0.440789773	16	0.177342272	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	K16070|0|hsa:203102|ADAM32; ADAM metallopeptidase domain 32; K16070 disintegrin and metalloproteinase domain-containing protein 32 [EC:3.4.24.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Reprolysin (M12B) family zinc metalloprotease;; ADAM cysteine-rich;; Reprolysin family propeptide;; Disintegrin	Disintegrin and metalloproteinase domain-containing protein 32 (Precursor) GN=ADAM32 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: disintegrin and metalloproteinase domain-containing protein 32 [Orycteropus afer afer]
ENSG00000197142(ACSL5)	--	0.033954231	2	0.084282258	5	0.016784599	0	0.429502083	26	0.588965	35	0.354417003	21	0.005401964	2.937698947	up	0.002225867	2.468652321	up	0.00217057	3.892046042	up	8.56E-07	3.525711682	up	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: metabolic process (GO:0008152);; 	"K01897|0|hsa:51703|ACSL5, ACS2, ACS5, FACL5; acyl-CoA synthetase long-chain family member 5 (EC:6.2.1.3); K01897 long-chain acyl-CoA synthetase [EC:6.2.1.3] (A)"	Fatty acid biosynthesis (ko00061);; Fatty acid degradation (ko00071);; Fatty acid metabolism (ko01212);; PPAR signaling pathway (ko03320);; Peroxisome (ko04146);; Adipocytokine signaling pathway (ko04920)	[I]	Lipid transport and metabolism	AMP-binding enzyme	Long-chain-fatty-acid--CoA ligase 5 GN=ACSL5 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: long-chain-fatty-acid--CoA ligase 5 isoform X1 [Tupaia chinensis]
ENSG00000197147(LRRC8B)	--	4.848121402	428	5.3943042	451	4.622434444	380	4.396117032	432	6.717404	516	3.855019022	360	0.970175882	-0.017349756	normal	0.954451244	0.1722767	normal	0.965797582	-0.085942505	normal	0.93492335	0.033266833	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine-rich repeat containing protein 8;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat	Volume-regulated anion channel subunit LRRC8B GN=LRRC8B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 8B [Orcinus orca]
ENSG00000197150(ABCB8)	--	18.5325299	970	19.53562407	967	19.8552328	979	19.85009814	947	19.12468502	1032	20.86025356	1063	0.977401069	-0.065347822	normal	0.977072532	0.07231913	normal	0.974918517	0.110305829	normal	0.89158029	0.040227599	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05655|0|hsa:11194|ABCB8, EST328128, M-ABC1, MABC1; ATP-binding cassette, sub-family B (MDR/TAP), member 8; K05655 ATP-binding cassette, subfamily B (MDR/TAP), member 8 (A)"	ABC transporters (ko02010)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ABC transporter transmembrane region;; ABC transporter	"ATP-binding cassette sub-family B member 8, mitochondrial (Precursor) GN=ABCB8 OS=Homo sapiens (Human) PE=1 SV=3"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: ATP-binding cassette sub-family B member 8, mitochondrial isoform X1 [Galeopterus variegatus]"
ENSG00000197153(HIST1H3J)	--	1.47072	4	0	0	1.66554	4	0.326743	1	1.75821	4	0.345918	1	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000197157(SND1)	--	71.53534251	5204	68.40351651	4974	70.99014092	5145	78.40080078	5693	82.87713902	5889	79.028914	5719	0.992489683	0.098708007	normal	0.982835164	0.222127481	normal	0.990486324	0.144260151	normal	0.458762106	0.154030719	normal	[L]	"Replication, recombination and repair"	--	"K15979|0|hsa:27044|SND1, TDRD11, p100; staphylococcal nuclease and tudor domain containing 1; K15979 staphylococcal nuclease domain-containing protein 1 (A)"	Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	Staphylococcal nuclease homologue;; Tudor domain	Staphylococcal nuclease domain-containing protein 1 GN=SND1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: staphylococcal nuclease domain-containing protein 1 [Panthera tigris altaica]
ENSG00000197162(ZNF785)	--	0.123321259	7	0.067322195	4	0.140619309	7	0.072317559	4	0.050165748	2	0.120367164	7	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:146540|ZNF785; zinc finger protein 785; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; LYAR-type C2HC zinc finger;; Zinc-finger double-stranded RNA-binding;; DNA Polymerase alpha zinc finger"	Zinc finger protein 785 GN=ZNF785 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 785 [Ceratotherium simum simum]
ENSG00000197168(NEK5)	--	0.091290626	4	0.116023324	7	0.032946077	1	0.045223086	2	0.03238159	1	0.033007379	2	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08857|0|hsa:341676|NEK5; NIMA-related kinase 5 (EC:2.7.11.1); K08857 NIMA (never in mitosis gene a)-related kinase [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase Nek5 GN=NEK5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase Nek5 [Ceratotherium simum simum]
ENSG00000197170(PSMD12)	--	42.02880796	2046	46.9929067	2245	44.50760605	2044	46.8388581	2470	49.71240806	2580	40.91786804	2109	0.962478905	0.240707933	normal	0.978129385	0.179116442	normal	0.98688242	0.036845619	normal	0.428738583	0.154721393	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	"K03035|0|ptr:454836|PSMD12; proteasome (prosome, macropain) 26S subunit, non-ATPase, 12; K03035 26S proteasome regulatory subunit N5 (A)"	Proteasome (ko03050);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	PCI domain	26S proteasome non-ATPase regulatory subunit 12 GN=PSMD12 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: 26S proteasome non-ATPase regulatory subunit 12 isoform X1 [Mustela putorius furo] 
ENSG00000197172(MAGEA6)	--	25.55831653	763	26.34210132	806	27.22817335	828	3.836931852	116	4.261533236	129	3.895587939	116	0	-2.732076524	down	0	-2.650580911	down	0	-2.827682255	down	1.47E-54	-2.75220383	down	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 6 GN=MAGEA6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: melanoma-associated antigen 10-like [Myotis brandtii]
ENSG00000197177(ADGRA1)	--	0	0	0	0	0.054056358	4	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08460|0|hsa:84435|GPR123, ADGRA1; G protein-coupled receptor 123; K08460 G protein-coupled receptor 123 (A)"	--	--	--	7 transmembrane receptor (Secretin family)	Probable G-protein coupled receptor 123 GN=GPR123 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	"putative G-protein coupled receptor 123, partial [Tupaia chinensis]"
ENSG00000197181(PIWIL2)	--	0.189894304	18	0.126033055	12	0.092575958	8	0.342881869	33	0.242298009	21	0.187806206	18	0.92953302	0.793016782	normal	0.97262599	0.716933044	normal	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: protein binding (GO:0005515);; 	"K02156|0|hsa:55124|PIWIL2, CT80, HILI, PIWIL1L, mili; piwi-like RNA-mediated gene silencing 2; K02156 aubergine (A)"	Dorso-ventral axis formation (ko04320)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Piwi domain;; PAZ domain	Piwi-like protein 2 GN=PIWIL2 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: piwi-like protein 2 [Oryctolagus cuniculus] 
ENSG00000197183(NOL4L)	--	11.01778204	997	13.33450085	936	13.40751852	974	9.986653679	784	10.001087	836	9.1322741	754	0.777014246	-0.376915251	normal	0.960241163	-0.184117174	normal	0.777493056	-0.376981542	normal	0.076690807	-0.313442341	normal	--	--	--	--	--	--	--	--	Nucleolar protein 4-like GN=NOL4L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C20orf112 homolog [Odobenus rosmarus divergens]
ENSG00000197191(CYSRT1)	--	1.83136	41	1.85561	42	1.65971	38	1.28658	29	0.910136	20	1.82638	42	0.958438798	-0.507666765	normal	0.663986181	-1.036563082	normal	0.980195816	0.131132806	normal	0.536347176	-0.431358851	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF2477)	Cysteine-rich tail protein 1 GN=CYSRT1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0574 protein C9orf169 homolog isoform X2 [Equus przewalskii]
ENSG00000197208(SLC22A4)	--	2.12517	73	1.33819	47	2.22968	78	2.21463	77	2.57927	88	2.6507	92	0.973848664	0.04520335	normal	0.340267568	0.86282392	normal	0.961066034	0.225832571	normal	0.496086098	0.356209473	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08202|0|hsa:6583|SLC22A4, OCTN1; solute carrier family 22 (organic cation/zwitterion transporter), member 4; K08202 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5 (A)"	Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 4 GN=SLC22A4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	solute carrier family 22 member 4 [Oryctolagus cuniculus] 
ENSG00000197223(C1D)	--	19.5212975	348	26.28063482	401	21.5746117	334	20.74612309	348	18.1933897	281	17.5734111	280	0.968247196	-0.030696737	normal	0.376192747	-0.532048165	normal	0.922381706	-0.261418193	normal	0.296611368	-0.274837305	normal	--	--	--	"K12592|1.28229e-98|hsa:10438|C1D, LRP1, Rrp47, SUN-CoR, SUNCOR, hC1D; C1D nuclear receptor corepressor; K12592 exosome complex protein LRP1 (A)"	RNA degradation (ko03018)	[L]	"Replication, recombination and repair"	Sas10/Utp3/C1D family	Nuclear nucleic acid-binding protein C1D GN=C1D OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear nucleic acid-binding protein C1D isoform X1 [Ursus maritimus]
ENSG00000197226(TBC1D9B)	--	31.74067246	3680	31.69487768	3743	32.25146257	3830	32.4082368	3762	32.79737015	3790	32.08917811	3743	0.991719514	0.000961422	normal	0.991528743	-0.003422384	normal	0.991518159	-0.04142424	normal	0.961668997	-0.015767417	normal	--	--	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; GRAM domain	TBC1 domain family member 9B GN=TBC1D9B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: TBC1 domain family member 9B isoform X1 [Oryctolagus cuniculus]
ENSG00000197233(OR1J2)	--	0.102843	1	0	0	0	0	0.203861	2	0	0	0.102052	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:26740|OR1J2, HG152, HSA5, OR1J3, OR1J5, OR9-19, OST044; olfactory receptor, family 1, subfamily J, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 1J2 GN=OR1J2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	Olfactory receptor 1J2 [Pteropus alecto]
ENSG00000197238(HIST1H4J)	--	3.64186	6	6.82128	12	1.07744	1	4.61486	9	5.19779	8	3.37088	6	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	"Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000197241(SLC2A7)	--	0	0	0.0426273	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K12201|0|hsa:155184|SLC2A7, GLUT7; solute carrier family 2 (facilitated glucose transporter), member 7; K12201 MFS transporter, SP family, solute carrier family 2 (facilitated glucose/fructose transporter), member 7 (A)"	--	[G]	Carbohydrate transport and metabolism	Sugar (and other) transporter;; Major Facilitator Superfamily	"Solute carrier family 2, facilitated glucose transporter member 7 GN=SLC2A7 OS=Homo sapiens (Human) PE=2 SV=2"	P	Inorganic ion transport and metabolism	"PREDICTED: solute carrier family 2, facilitated glucose transporter member 7 [Tupaia chinensis]"
ENSG00000197245(FAM110D)	--	0.0225581	1	0.0217769	1	0	0	0.0443449	2	0.0217025	0	0.0442108	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Centrosome-associated C terminus;; Centrosome-associated N terminus	Protein FAM110D GN=FAM110D OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM110D [Camelus bactrianus] 
ENSG00000197249(SERPINA1)	--	0.157918516	5	0.015701954	1	0.211236533	5	0.133627065	6	0.396924241	3	0.278124707	4	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K03984|0|hsa:5265|SERPINA1, A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1; K03984 alpha-1-antitrypsin (A)"	Complement and coagulation cascades (ko04610)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Short peptide from AAT (Precursor) GN=SERPINA1 OS=Homo sapiens (Human) PE=1 SV=3	V	Defense mechanisms	"PREDICTED: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 isoform X1 [Canis lupus familiaris] "
ENSG00000197256(KANK2)	--	15.83840465	1714	20.76672347	1897	17.7770258	1853	11.27078529	1146	10.48813036	1138	10.29511026	1070	0.045648228	-0.610917604	normal	0.001414416	-0.75785666	normal	0.000323926	-0.799673642	normal	2.11E-07	-0.725428147	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; KN motif;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	KN motif and ankyrin repeat domain-containing protein 2 GN=KANK2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: KN motif and ankyrin repeat domain-containing protein 2 [Ursus maritimus]
ENSG00000197261(C6orf141)	--	9.58697	806	6.27339	486	7.63735	593	7.61438	422	12.31924	809	7.01386	352	1.02E-05	-0.961788207	normal	0.009694516	0.712022137	normal	0.004761694	-0.758209426	normal	0.737434437	-0.273139209	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C6orf141 GN=C6orf141 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C6orf141 homolog [Galeopterus variegatus]
ENSG00000197265(GTF2E2)	--	28.97208175	914	25.2774258	809	27.32357143	864	29.45973983	937	29.93946262	943	25.06615041	791	0.978637849	0.005014294	normal	0.955919161	0.199346091	normal	0.968985351	-0.135397285	normal	0.940575645	0.024489131	normal	[K]	Transcription	Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	"K03137|0|ptr:464098|GTF2E2; general transcription factor IIE, polypeptide 2, beta 34kDa; K03137 transcription initiation factor TFIIE subunit beta (A)"	Basal transcription factors (ko03022);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[K]	Transcription	TFIIE beta subunit core domain	Transcription initiation factor IIE subunit beta GN=GTF2E2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor IIE subunit 2-like [Balaenoptera acutorostrata scammoni]
ENSG00000197275(RAD54B)	--	10.09562809	513	11.00586119	547	11.85179638	588	12.5511072	582	8.760477369	385	7.748742218	359	0.960843657	0.150803843	normal	0.328627247	-0.526364762	normal	0.011642105	-0.717736867	normal	0.277519935	-0.336282858	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K10877|0|ptr:472821|RAD54B; RAD54 homolog B (S. cerevisiae); K10877 DNA repair and recombination protein RAD54B [EC:3.6.4.-] (A)	Homologous recombination (ko03440)	[L]	"Replication, recombination and repair"	"SNF2 family N-terminal domain;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit;; Class II histone deacetylase complex subunits 2 and 3"	DNA repair and recombination protein RAD54B GN=RAD54B OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA repair and recombination protein RAD54B [Ceratotherium simum simum]
ENSG00000197279(ZNF165)	--	0.532023094	26	0.6813156	22	0.740008103	20	0.463224296	24	0.43502111	22	1.119963846	58	0.986354166	-0.137829102	normal	0.987199937	-0.020048445	normal	0.024667906	1.460131954	normal	0.582525764	0.594234981	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:7718|ZNF165, CT53, LD65, ZSCAN7; zinc finger protein 165; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"SCAN domain;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 165 GN=ZNF165 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 165 [Ceratotherium simum simum]
ENSG00000197283(SYNGAP1)	--	8.735228019	740	6.750908838	765	5.979285038	713	7.209493576	650	6.607456851	557	7.015410705	642	0.945966765	-0.217435678	normal	0.463857995	-0.47809631	normal	0.962098906	-0.15926405	normal	0.148532321	-0.28391295	normal	--	--	Biological Process: regulation of GTPase activity (GO:0043087);; 	"K17631|0|hsa:8831|SYNGAP1, MRD5, RASA1, RASA5, SYNGAP; synaptic Ras GTPase activating protein 1; K17631 Ras/Rap GTPase-activating protein SynGAP (A)"	Ras signaling pathway (ko04014)	[R]	General function prediction only	Domain of unknown function (DUF3498);; GTPase-activator protein for Ras-like GTPase;; C2 domain	Ras/Rap GTPase-activating protein SynGAP GN=SYNGAP1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: ras GTPase-activating protein SynGAP [Ochotona princeps]
ENSG00000197296(FITM2)	--	7.00217	543	7.34203	575	6.43527	497	6.87924	535	6.63382	510	6.80249	528	0.971299939	-0.052097058	normal	0.950119596	-0.193949242	normal	0.96925494	0.078768072	normal	0.85521395	-0.059479834	normal	--	--	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: lipid storage (GO:0019915);; 	--	--	[I]	Lipid transport and metabolism	Inositol phospholipid synthesis and fat-storage-inducing TM	Fat storage-inducing transmembrane protein 2 GN=FITM2 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	hypothetical protein PANDA_005624 [Ailuropoda melanoleuca]
ENSG00000197299(BLM)	--	8.029276975	785	8.033753364	804	9.565241145	916	6.062721534	612	6.764750494	678	5.911195205	596	0.745706013	-0.389128098	normal	0.922535069	-0.266789559	normal	0.043691879	-0.627033213	normal	0.012357917	-0.430429026	normal	[L]	"Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: intracellular (GO:0005622);; Cellular Component: nucleus (GO:0005634);; Biological Process: DNA replication (GO:0006260);; Biological Process: DNA repair (GO:0006281);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; Molecular Function: ATP-dependent 3'-5' DNA helicase activity (GO:0043140);; "	"K10901|0|hsa:641|BLM, BS, RECQ2, RECQL2, RECQL3; Bloom syndrome, RecQ helicase-like (EC:3.6.4.12); K10901 bloom syndrome protein [EC:3.6.4.12] (A)"	Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	RQC domain;; BDHCT (NUC031) domain;; DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; HRDC domain	Bloom syndrome protein GN=BLM OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: Bloom syndrome protein [Ceratotherium simum simum]
ENSG00000197302(ZNF720)	--	6.025037636	485	6.824568163	531	8.574868682	515	7.708521198	499	6.01193416	544	6.105818262	553	0.971525828	0.010190978	normal	0.97174154	0.013430443	normal	0.968393983	0.094148761	normal	0.910162737	0.039134378	normal	--	--	--	K09228|1.64817e-31|cfa:484323|ZNF682; zinc finger protein 347-like; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	--	Putative protein ZNF720 GN=ZNF720 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 347 isoform X1 [Canis lupus familiaris]
ENSG00000197312(DDI2)	--	5.35137	839	5.152687	829	6.74075	861	5.689835	974	5.73239	909	6.56404	1037	0.960831745	0.184105584	normal	0.972100977	0.111287717	normal	0.931923751	0.259623235	normal	0.361360581	0.186424993	normal	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; 	K11885|0|ptr:739922|DDI2; protein DDI1 homolog 2; K11885 DNA damage-inducible protein 1 (A)	--	[L]	"Replication, recombination and repair"	Aspartyl protease;; Aspartyl protease;; Retroviral aspartyl protease;; Retroviral aspartyl protease;; Ubiquitin family	Protein DDI1 homolog 2 GN=DDI2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: regulatory solute carrier protein family 1 member 1-like isoform X2 [Tupaia chinensis]
ENSG00000197321(SVIL)	--	10.70402116	1837	12.75063704	2194	11.61139768	2002	8.814474784	1531	7.559951789	1319	9.446568703	1634	0.925275204	-0.293440312	normal	0.00145397	-0.754866791	normal	0.922084588	-0.301073239	normal	0.002511612	-0.449200331	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cytoskeleton organization (GO:0007010);; 	K10369|0|ptr:450874|SVIL; supervillin; K10369 supervillin (A)	--	[Z]	Cytoskeleton	Gelsolin repeat;; Villin headpiece domain	Supervillin GN=SVIL OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: supervillin isoform X6 [Equus caballus]
ENSG00000197323(TRIM33)	--	8.0191916	1048	7.821181262	1034	8.168464107	1041	8.32929741	1062	8.818853007	1121	7.3316492	931	0.98011794	-0.011670219	normal	0.97649187	0.094990085	normal	0.965789254	-0.169148452	normal	0.936208879	-0.025671333	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	"K08883|0|hsa:51592|TRIM33, ECTO, PTC7, RFG7, TF1G, TIF1G, TIF1GAMMA, TIFGAMMA; tripartite motif containing 33; K08883 tripartite motif-containing protein 33 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Bromodomain;; B-box zinc finger;; PHD-finger;; Ring finger domain	E3 ubiquitin-protein ligase TRIM33 GN=TRIM33 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: E3 ubiquitin-protein ligase TRIM33 isoform 1 [Odobenus rosmarus divergens]
ENSG00000197324(LRP10)	--	98.7797704	5426	102.764345	5486	93.830092	5030	87.763396	5097	89.839782	5266	114.5662892	6372	0.991458994	-0.121037586	normal	0.992685091	-0.08045102	normal	0.942685504	0.332807327	normal	0.858121989	0.049361952	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Low-density lipoprotein receptor domain class A;; CUB domain	Low-density lipoprotein receptor-related protein 10 (Precursor) GN=LRP10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor-related protein 10 [Ceratotherium simum simum]
ENSG00000197329(PELI1)	--	1.286557101	72	1.203847871	68	1.137268741	63	1.856773731	105	2.663054	150	1.932385592	109	0.85031478	0.504527669	normal	0.002668475	1.103008301	up	0.372469153	0.768423373	normal	0.025281473	0.821378527	normal	--	--	Biological Process: Toll signaling pathway (GO:0008063);; 	K11964|0|umr:103671316|PELI1; pellino E3 ubiquitin protein ligase 1; K11964 pellino (A)	--	[T]	Signal transduction mechanisms	Pellino	E3 ubiquitin-protein ligase pellino homolog 1 GN=PELI1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: E3 ubiquitin-protein ligase pellino homolog 1 [Oryctolagus cuniculus] 
ENSG00000197343(ZNF655)	--	23.26170242	1078	21.32060026	1037	22.62433738	978	28.01888721	1290	21.86122717	1066	22.40541617	1087	0.952254227	0.227884414	normal	0.979554286	0.018338609	normal	0.970932024	0.143942916	normal	0.539707827	0.132751426	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 655 GN=ZNF655 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 655 [Orcinus orca]
ENSG00000197345(MRPL21)	--	51.558796	421	49.703009	409	56.51995	474	61.630258	517	59.418492	477	46.883662	388	0.918204066	0.264639057	normal	0.946300303	0.199777331	normal	0.895901489	-0.296075942	normal	0.854699695	0.062048503	normal	--	--	Cellular Component: ribosome (GO:0005840);; 	"K02888|8.91308e-131|hsa:219927|MRPL21, L21mt, MRP-L21; mitochondrial ribosomal protein L21; K02888 large subunit ribosomal protein L21 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal prokaryotic L21 protein	"39S ribosomal protein L21, mitochondrial (Precursor) GN=MRPL21 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L21, mitochondrial [Galeopterus variegatus]"
ENSG00000197355(UAP1L1)	--	7.19490681	494	9.551084058	657	6.110576107	423	4.704116081	313	4.86371809	328	12.28960548	835	0.029064923	-0.686473081	normal	5.43E-06	-1.020230879	down	7.78E-06	0.970311239	normal	0.926977546	-0.111522756	normal	--	--	Biological Process: metabolic process (GO:0008152);; Molecular Function: uridylyltransferase activity (GO:0070569);; 	K00972|0|hsa:91373|UAP1L1; UDP-N-acetylglucosamine pyrophosphorylase 1 like 1; K00972 UDP-N-acetylglucosamine/UDP-N-acetylgalactosamine diphosphorylase [EC:2.7.7.23 2.7.7.83] (A)	Amino sugar and nucleotide sugar metabolism (ko00520)	[M]	Cell wall/membrane/envelope biogenesis	UTP--glucose-1-phosphate uridylyltransferase	UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 GN=UAP1L1 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: LOW QUALITY PROTEIN: UDP-N-acetylhexosamine pyrophosphorylase-like protein 1 [Loxodonta africana]
ENSG00000197361(FBXL22)	--	0.435548485	17	0.2592222	16	0.418099765	25	0.439153602	26	0.284603007	15	0.589640801	21	0.976622199	0.542282836	normal	--	--	--	0.985404743	-0.243724965	normal	0.967880881	0.074884387	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10288|2.57818e-130|hsa:283807|FBXL22, Fbl22; F-box and leucine-rich repeat protein 22 (EC:3.4.19.12); K10288 F-box and leucine-rich repeat protein 22 (A)"	--	--	--	F-box-like;; F-box domain	F-box and leucine-rich protein 22 GN=FBXL22 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: F-box and leucine-rich protein 22-like [Sus scrofa]
ENSG00000197362(ZNF786)	--	4.206953	268	4.286614	284	3.492166	233	3.774985	253	4.719043	313	4.740012	304	0.961605875	-0.113259442	normal	0.960328595	0.118245244	normal	0.830071215	0.373322701	normal	0.719950803	0.127427725	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:136051|ZNF786; zinc finger protein 786; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 786 GN=ZNF786 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 786 [Ceratotherium simum simum]
ENSG00000197363(ZNF517)	--	5.643901183	238	4.024165587	192	5.390885059	224	3.814994509	187	5.451181845	248	4.649547681	222	0.847574699	-0.376009444	normal	0.875045978	0.345407781	normal	0.966840749	-0.02108749	normal	0.984600345	-0.013876593	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:340385|ZNF517; zinc finger protein 517; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 517 GN=ZNF517 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 517 [Ursus maritimus]
ENSG00000197372(ZNF675)	--	3.340567031	170	4.6834012	233	4.362726001	197	3.991363954	197	3.707518	179	4.267494126	173	0.953692643	0.180313817	normal	0.822510462	-0.398834189	normal	0.950979253	-0.194123622	normal	0.716297523	-0.1498644	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:171392|ZNF675, TBZF, TIZ; zinc finger protein 675; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; C1-like domain;; SprT-like family"	Zinc finger protein 675 GN=ZNF675 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000197375(SLC22A5)	--	10.590552	562	9.75687	524	11.240169	598	18.622219	989	17.56016	927	17.991244	955	0.00105988	0.782934783	normal	0.000974392	0.799818222	normal	0.018711083	0.665719748	normal	1.45E-06	0.748534227	normal	[GEPR]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; Inorganic ion transport and metabolism;; General function prediction only	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	"K08202|0|hsa:6584|SLC22A5, CDSP, OCTN2, OCTN2VT; solute carrier family 22 (organic cation/carnitine transporter), member 5; K08202 MFS transporter, OCT family, solute carrier family 22 (organic cation transporter), member 4/5 (A)"	Choline metabolism in cancer (ko05231)	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Solute carrier family 22 member 5 GN=SLC22A5 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: solute carrier family 22 member 5 [Ceratotherium simum simum]
ENSG00000197380(DACT3)	--	0.34774259	15	0.141490876	5	0.191028113	6	0.086174925	3	0.14524183	6	0.028234402	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Dapper	Dapper homolog 3 GN=DACT3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dapper homolog 3 [Sus scrofa]
ENSG00000197381(ADARB1)	--	1.70145662	152	1.406537228	123	1.280614065	121	2.852244716	204	1.946219106	162	2.28065914	212	0.851359622	0.390250244	normal	0.887448192	0.371913571	normal	0.046464342	0.793181737	normal	0.09329068	0.52421496	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: adenosine deaminase activity (GO:0004000);; Biological Process: RNA processing (GO:0006396);; 	"K13194|0|pps:100983816|ADARB1; adenosine deaminase, RNA-specific, B1; K13194 double stranded RNA-specific editase B [EC:3.5.-.-] (A)"	--	[A]	RNA processing and modification	Adenosine-deaminase (editase) domain;; Double-stranded RNA binding motif;; Putative binding domain	Double-stranded RNA-specific editase 1 GN=ADARB1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: double-stranded RNA-specific editase 1 [Galeopterus variegatus]
ENSG00000197385(ZNF860)	--	0.680475447	40	0.706744892	41	0.691990043	46	0.71280171	43	0.51973223	33	0.644527446	39	0.981065813	0.070878393	normal	0.972703329	-0.321345821	normal	0.975625143	-0.237945847	normal	0.850390153	-0.164574403	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:344787|ZNF860; zinc finger protein 860; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 860 GN=ZNF860 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 347-like [Galeopterus variegatus]
ENSG00000197386(HTT)	--	7.259499181	1945	9.020977812	2166	7.558186	2071	7.505429603	2037	7.855552354	2128	7.415086501	2021	0.986496765	0.035815915	normal	0.986634666	-0.046928593	normal	0.986606985	-0.043517505	normal	0.949356766	-0.020260252	normal	--	--	--	"K04533|0|hsa:3064|HTT, HD, IT15; huntingtin; K04533 huntingtin (A)"	Huntington's disease (ko05016)	--	--	Huntingtin protein region;; HEAT repeat;; HEAT repeats;; HEAT-like repeat	Huntingtin GN=HTT OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: huntingtin [Tupaia chinensis]
ENSG00000197405(C5AR1)	--	0.9435137	66	2.431921	120	1.710477137	88	0.766741	40	0.91672	47	1.7561926	82	0.76127758	-0.731199416	normal	0.000342557	-1.345639345	down	0.970197243	-0.108243582	normal	0.224135916	-0.716406474	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04010|0|hsa:728|C5AR1, C5A, C5AR, C5R1, CD88; complement component 5a receptor 1; K04010 C5a anaphylatoxin chemotactic receptor (A)"	Neuroactive ligand-receptor interaction (ko04080);; Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150)	--	--	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	C5a anaphylatoxin chemotactic receptor 1 GN=C5AR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: C5a anaphylatoxin chemotactic receptor 1-like [Galeopterus variegatus]
ENSG00000197406(DIO3)	--	0.185145	6	0.242319	8	0.147888	4	0.152752	5	0.0595336	1	0.121472	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: thyroxine 5'-deiodinase activity (GO:0004800);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K07754|0|hsa:1735|DIO3, 5DIII, D3, DIOIII, TXDI3; deiodinase, iodothyronine, type III (EC:1.97.1.11); K07754 thyroxine 5-deiodinase [EC:1.97.1.11] (A)"	Thyroid hormone signaling pathway (ko04919)	--	--	Iodothyronine deiodinase;; Iodothyronine deiodinase	Type III iodothyronine deiodinase GN=DIO3 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: type III iodothyronine deiodinase [Galeopterus variegatus]
ENSG00000197410(DCHS2)	--	0.034763047	4	0.037463518	5	0.036211853	3	0.031639111	3	0.051147945	4	0.082479981	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	K16507|0|pps:100993387|DCHS2; dachsous cadherin-related 2; K16507 protocadherin-16/23 (A)	--	[S]	Function unknown	Cadherin domain;; Cadherin-like;; Cadherin prodomain like	Protocadherin-23 GN=DCHS2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protocadherin-23-like [Galeopterus variegatus]
ENSG00000197415(VEPH1)	--	0.096118841	3	0.266135226	7	0.30472589	9	0.476367489	19	0.892577302	39	1.711565603	84	--	--	--	0.00294516	2.231618245	up	5.53E-11	3.016433365	up	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	PH domain;; Pleckstrin homology domain	Ventricular zone-expressed PH domain-containing protein homolog 1 GN=VEPH1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: ventricular zone-expressed PH domain-containing protein homolog 1 isoform X1 [Myotis davidii] 
ENSG00000197429(IPP)	--	6.755708	325	5.60208	272	5.96744	295	4.285119042	216	4.23912085	209	4.460799	213	0.180162755	-0.616637669	normal	0.804083988	-0.398991561	normal	0.630280511	-0.475272671	normal	0.042035004	-0.504711484	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K13956|0|mcf:102144215|IPP; intracisternal A particle-promoted polypeptide; K13956 actin-binding protein IPP (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; BTB And C-terminal Kelch;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Actin-binding protein IPP GN=IPP OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: actin-binding protein IPP isoform X1 [Ursus maritimus]
ENSG00000197442(MAP3K5)	--	1.409561946	135	1.126629879	117	1.269604504	134	1.58653099	138	1.131993	118	1.588525612	168	0.968466151	0.000866839	normal	0.968113258	-0.009031983	normal	0.918355004	0.314757988	normal	0.828193378	0.114944721	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04426|0|hsa:4217|MAP3K5, ASK1, MAPKKK5, MEKK5; mitogen-activated protein kinase kinase kinase 5 (EC:2.7.11.25); K04426 mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25] (A)"	MAPK signaling pathway (ko04010);; Sphingolipid signaling pathway (ko04071);; Protein processing in endoplasmic reticulum (ko04141);; TNF signaling pathway (ko04668);; Neurotrophin signaling pathway (ko04722);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Amyotrophic lateral sclerosis (ALS) (ko05014)	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4071);; Protein kinase domain;; Protein tyrosine kinase	Mitogen-activated protein kinase kinase kinase 5 GN=MAP3K5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 5 [Galeopterus variegatus]
ENSG00000197444(OGDHL)	--	0.223294254	16	0.125280019	10	0.257890851	20	0.126888841	9	0.206815963	15	0.154894314	12	--	--	--	--	--	--	0.977463343	-0.678425031	normal	--	--	--	[C]	Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor (GO:0016624);; "	K00164|0|pps:100975720|OGDHL; oxoglutarate dehydrogenase-like; K00164 2-oxoglutarate dehydrogenase E1 component [EC:1.2.4.2] (A)	Citrate cycle (TCA cycle) (ko00020);; Lysine degradation (ko00310);; Tryptophan metabolism (ko00380);; Carbon metabolism (ko01200)	[G]	Carbohydrate transport and metabolism	"Dehydrogenase E1 component;; Transketolase, pyrimidine binding domain"	"2-oxoglutarate dehydrogenase-like, mitochondrial (Precursor) GN=OGDHL OS=Homo sapiens (Human) PE=1 SV=3"	G	Carbohydrate transport and metabolism	"PREDICTED: 2-oxoglutarate dehydrogenase-like, mitochondrial isoform X2 [Erinaceus europaeus]"
ENSG00000197446(CYP2F1)	--	1.061038044	5	0.218361	1	0.06745653	1	0.209805	1	0.585481037	2	0.434986	2	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K07416|0|hsa:1572|CYP2F1, C2F1, CYP2F; cytochrome P450, family 2, subfamily F, polypeptide 1 (EC:1.14.14.1); K07416 cytochrome P450, family 2, subfamily F [EC:1.14.14.1] (A)"	Metabolism of xenobiotics by cytochrome P450 (ko00980)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2F1 GN=CYP2F1 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	hypothetical protein PANDA_012937 [Ailuropoda melanoleuca]
ENSG00000197448(GSTK1)	--	63.48683541	1105	61.06700134	1058	55.10302243	990	60.30395147	1067	64.57859353	1121	68.68112166	1223	0.97801491	-0.081203543	normal	0.978686533	0.061934085	normal	0.908869377	0.296224695	normal	0.699801496	0.092547271	normal	--	--	Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; 	"K13299|0|hsa:373156|GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1; glutathione S-transferase kappa 1 (EC:2.5.1.18); K13299 glutathione S-transferase kappa 1 [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Peroxisome (ko04146);; Chemical carcinogenesis (ko05204)	--	--	DSBA-like thioredoxin domain	Glutathione S-transferase kappa 1 GN=GSTK1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase kappa 1 [Tupaia chinensis]
ENSG00000197451(HNRNPAB)	--	153.3393446	5051	145.2011247	4951	156.8743281	5347	192.7600976	6479	188.2719156	6167	151.3039879	5007	0.946518968	0.328281495	normal	0.96433589	0.29534137	normal	0.992007712	-0.10304454	normal	0.360290855	0.179980599	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13044|2.79041e-130|hsa:3182|HNRNPAB, ABBP1, HNRPAB; heterogeneous nuclear ribonucleoprotein A/B; K13044 heterogeneous nuclear ribonucleoprotein A/B/D (A)"	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; CBFNT (NUC161) domain;; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Heterogeneous nuclear ribonucleoprotein A/B GN=HNRNPAB OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: heterogeneous nuclear ribonucleoprotein A/B isoform 2 [Dasypus novemcinctus]
ENSG00000197457(STMN3)	--	5.342514369	217	3.2881637	137	4.068219768	172	1.673355185	68	1.960986876	78	1.507930018	57	8.94E-10	-1.682415479	down	0.132675639	-0.821870056	normal	1.98E-07	-1.576374453	down	3.52E-05	-1.395105666	down	--	--	Biological Process: regulation of microtubule polymerization or depolymerization (GO:0031110);; 	--	--	--	--	Stathmin family	Stathmin-3 GN=STMN3 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: stathmin-3 isoform X3 [Mustela putorius furo]
ENSG00000197461(PDGFA)	--	12.1239491	484	11.01069343	446	11.02367304	447	18.34478734	722	17.13163967	688	14.44059	575	0.214801493	0.544735319	normal	0.100454445	0.602282105	normal	0.824573512	0.353937258	normal	0.005050196	0.505723806	normal	--	--	Molecular Function: growth factor activity (GO:0008083);; Cellular Component: membrane (GO:0016020);; 	"K04359|2.00711e-124|hsa:5154|PDGFA, PDGF-A, PDGF1; platelet-derived growth factor alpha polypeptide; K04359 platelet-derived growth factor subunit A (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Cytokine-cytokine receptor interaction (ko04060);; PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; Gap junction (ko04540);; Regulation of actin cytoskeleton (ko04810);; HTLV-I infection (ko05166);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Prostate cancer (ko05215);; Melanoma (ko05218);; Choline metabolism in cancer (ko05231)	--	--	"Platelet-derived growth factor, N terminal region;; PDGF/VEGF domain"	Platelet-derived growth factor subunit A (Precursor) GN=PDGFA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: platelet-derived growth factor subunit A isoform X1 [Galeopterus variegatus]
ENSG00000197467(COL13A1)	--	0.239741585	13	0.040242861	2	0.103972	5	0.92602982	37	0.378758517	24	0.234709186	15	0.37963855	1.377959395	normal	0.013504621	2.844536946	normal	--	--	--	--	--	--	--	--	--	"K16617|0|hsa:1305|COL13A1, COLXIIIA1; collagen, type XIII, alpha 1; K16617 collagen, type XIII, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	Collagen alpha-1(XIII) chain OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: collagen alpha-1(XIII) chain isoform X1 [Vicugna pacos]
ENSG00000197472(ZNF695)	--	0.868490781	15	2.739217	42	1.299068	19	1.36874447	25	0.51421123	10	1.631597	29	0.971529474	0.653817917	normal	0.007827825	-1.937895646	down	0.970046324	0.565121626	normal	0.855748348	-0.269830307	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; XPA protein N-terminal;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 695 GN=ZNF695 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000197479(PCDHB11)	--	0.284688902	19	0.475118499	26	0.295319762	19	0.2049557	10	0.115757226	7	0.118318158	8	--	--	--	0.37188979	-1.711392538	normal	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16494|0|hsa:56125|PCDHB11, ME2, PCDH-BETA11; protocadherin beta 11; K16494 protocadherin beta (A)"	--	[S]	Function unknown	Cadherin domain;; Cadherin-like	Protocadherin beta-11 (Precursor) GN=PCDHB11 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protocadherin beta-11-like [Equus caballus]
ENSG00000197483(ZNF628)	--	4.260553635	241	7.020623277	272	4.248904721	168	6.49983489	211	5.680477	197	3.530091	194	0.941869024	-0.221114435	normal	0.631823425	-0.483663043	normal	0.950558665	0.197647036	normal	0.598083532	-0.200074596	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; GAGA factor;; Zinc-finger of C2H2 type"	Zinc finger protein 628 GN=ZNF628 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 628 [Galeopterus variegatus]
ENSG00000197498(RPF2)	--	14.0619829	531	14.27187971	574	14.53778704	579	14.93954132	617	14.22414205	558	14.69630521	627	0.953660007	0.185228835	normal	0.970682844	-0.062046367	normal	0.968539672	0.106343678	normal	0.795856834	0.076588553	normal	[S]	Function unknown	--	"K14847|0|ptr:462940|RPF2, BXDC1; ribosome production factor 2 homolog (S. cerevisiae); K14847 ribosome production factor 2 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Brix domain	Ribosome production factor 2 homolog GN=RPF2 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosome production factor 2 homolog [Mustela putorius furo] 
ENSG00000197530(MIB2)	--	5.643287618	332	5.593309806	381	5.715193714	312	4.083520265	256	4.655239708	301	6.933065213	415	0.770561485	-0.403737039	normal	0.832435307	-0.359842994	normal	0.753158962	0.401580676	normal	0.839424806	-0.096597671	normal	[R]	General function prediction only	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein ubiquitination (GO:0016567);; Molecular Function: metal ion binding (GO:0046872);; 	"K10645|0|hsa:142678|MIB2, ZZANK1, ZZZ5; mindbomb E3 ubiquitin protein ligase 2; K10645 E3 ubiquitin-protein ligase mind-bomb [EC:6.3.2.19] (A)"	--	[R]	General function prediction only	"Mib_herc2;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, ZZ type"	E3 ubiquitin-protein ligase MIB2 GN=MIB2 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MIB2 isoform X1 [Tupaia chinensis]
ENSG00000197535(MYO5A)	--	13.79960061	2687	15.092485	2890	16.80625481	3112	12.29851373	2481	10.98259774	2323	13.50556425	2595	0.983317749	-0.145820042	normal	0.906066584	-0.336310166	normal	0.956668096	-0.270254934	normal	0.138086753	-0.252761387	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10357|0|hsa:4644|MYO5A, GS1, MYH12, MYO5, MYR12; myosin VA (heavy chain 12, myoxin); K10357 myosin V (A)"	--	[Z]	Cytoskeleton	Myosin head (motor domain);; DIL domain;; IQ calmodulin-binding motif	Unconventional myosin-Va GN=MYO5A OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	myosin Va [Sus scrofa]
ENSG00000197536(C5orf56)	--	2.691906	76	2.497415	77	1.60625	69	2.660648	67	2.536154	64	1.936929	66	0.967068462	-0.208184346	normal	0.957272975	-0.282125835	normal	0.974396605	-0.070834245	normal	0.762955092	-0.1937983	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C5orf56 GN=C5orf56 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C5orf56-like [Galeopterus variegatus]
ENSG00000197540(GZMM)	--	0.0782616	1	0.5999635	8	0.36461518	4	0	0	0.15176047	1	0.1519013	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	K08649|1.27812e-168|ggo:101130502|GZMM; granzyme M; K08649 granzyme M [EC:3.4.21.-] (A)	--	[E]	Amino acid transport and metabolism	Trypsin;; Trypsin-like peptidase domain	Granzyme M (Precursor) GN=GZMM OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: granzyme M [Myotis lucifugus]
ENSG00000197548(ATG7)	--	26.539403	679	16.96412693	544	23.69946698	648	11.7812513	499	14.5623716	458	17.0975941	511	0.472372743	-0.473947419	normal	0.915986192	-0.268869853	normal	0.828997776	-0.350039781	normal	0.056559289	-0.370964855	normal	[H]	Coenzyme transport and metabolism	Molecular Function: small protein activating enzyme activity (GO:0008641);; 	K08337|0|mcf:101926188|hypothetical protein; K08337 ubiquitin-like modifier-activating enzyme ATG7 (A)	Regulation of autophagy (ko04140)	[H]	Coenzyme transport and metabolism	ThiF family	Ubiquitin-like modifier-activating enzyme ATG7 GN=ATG7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like modifier-activating enzyme ATG7 isoform 1 [Dasypus novemcinctus] 
ENSG00000197555(SIPA1L1)	--	4.873738437	618	4.841340323	606	5.300946784	625	4.089424656	528	4.27560358	589	4.576878198	624	0.92410416	-0.257208463	normal	0.971291519	-0.062318962	normal	0.974154739	-0.010575992	normal	0.688826333	-0.107455248	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	K17701|0|ptr:453008|SIPA1L1; signal-induced proliferation-associated 1 like 1; K17701 signal-induced proliferation-associated 1 like protein 1 (A)	Rap1 signaling pathway (ko04015)	[T]	Signal transduction mechanisms	Domain of unknown function (DUF3401);; Rap/ran-GAP;; PDZ domain (Also known as DHR or GLGF)	Signal-induced proliferation-associated 1-like protein 1 GN=SIPA1L1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: signal-induced proliferation-associated 1-like protein 1-like isoform X2 [Tupaia chinensis]
ENSG00000197557(TTC30A)	--	5.24362	485	5.36966	496	4.67378	426	3.43033	319	3.08242	284	3.49356	323	0.078123475	-0.632769111	normal	0.0020657	-0.822516566	normal	0.740340864	-0.405950236	normal	0.001646305	-0.624993882	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3"	Tetratricopeptide repeat protein 30A GN=TTC30A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: tetratricopeptide repeat protein 30A-like [Tursiops truncatus]
ENSG00000197558(SSPO)	--	0.551369423	163	0.523832761	158	0.328662781	104	0.112569995	34	0.178791953	53	0.284706617	74	8.74E-13	-2.241056738	down	6.62E-07	-1.570041962	down	0.859509495	-0.490776683	normal	0.000387082	-1.420026524	down	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[WV]	Extracellular structures;; Defense mechanisms	Thrombospondin type 1 domain;; von Willebrand factor type D domain;; Trypsin Inhibitor like cysteine rich domain;; C8 domain;; Low-density lipoprotein receptor domain class A;; Pacifastin inhibitor (LCMII);; F5/8 type C domain;; von Willebrand factor type C domain	SCO-spondin (Precursor) GN=SSPO OS=Homo sapiens (Human) PE=2 SV=1	PTVW	Inorganic ion transport and metabolism;; Signal transduction mechanisms;; Defense mechanisms;; Extracellular structures	PREDICTED: SCO-spondin [Ceratotherium simum simum]
ENSG00000197561(ELANE)	--	1.509015	18	1.178813561	14	0.330464145	3	0	0	0.168807875	1	0.086350534	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01327|1.55683e-163|hsa:1991|ELANE, ELA2, GE, HLE, HNE, NE, PMN-E, SCN1; elastase, neutrophil expressed (EC:3.4.21.37); K01327 leukocyte elastase [EC:3.4.21.37] (A)"	Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Neutrophil elastase (Precursor) GN=ELANE OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: neutrophil elastase [Galeopterus variegatus]
ENSG00000197562(RAB40C)	--	10.46880755	498	10.11938525	484	9.704192002	484	8.08006589	359	7.346756485	334	8.808908657	421	0.418602026	-0.50116395	normal	0.260627563	-0.554487102	normal	0.94431377	-0.2087782	normal	0.045150406	-0.416905016	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K07928|0|lve:103082305|RAB40C; RAB40C, member RAS oncogene family; K07928 Ras-related protein Rab-40 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; SOCS box;; ADP-ribosylation factor family	Ras-related protein Rab-40C GN=RAB40C OS=Homo sapiens (Human) PE=1 SV=1	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-40C isoform 1 [Orcinus orca] 
ENSG00000197563(PIGN)	--	14.64579702	877	13.00276935	807	13.87954566	862	13.05350454	836	12.06713514	769	11.86455956	774	0.973520996	-0.099727186	normal	0.972728689	-0.090837228	normal	0.964022195	-0.163343164	normal	0.617848946	-0.11926374	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: GPI anchor biosynthetic process (GO:0006506);; Biological Process: metabolic process (GO:0008152);; Molecular Function: sulfuric ester hydrolase activity (GO:0008484);; Molecular Function: transferase activity (GO:0016740);; 	"K05285|0|hsa:23556|PIGN, MCAHS, MCAHS1, MCD4, MDC4, PIG-N; phosphatidylinositol glycan anchor biosynthesis, class N; K05285 phosphatidylinositol glycan, class N [EC:2.7.-.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[T]	Signal transduction mechanisms	Phosphatidylinositolglycan class N (PIG-N);; Type I phosphodiesterase / nucleotide pyrophosphatase;; Sulfatase	GPI ethanolamine phosphate transferase 1 GN=PIGN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: GPI ethanolamine phosphate transferase 1 isoform X1 [Oryctolagus cuniculus]
ENSG00000197565(COL4A6)	--	9.0807196	1354	6.094227886	919	7.565232665	1131	23.59162225	3502	21.68036707	3183	14.26985645	2127	8.03E-14	1.339139949	up	0	1.769159681	up	1.16E-05	0.902035754	normal	0.0001464	1.349757143	up	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Cellular Component: collagen trimer (GO:0005581);; 	"K06237|0|hsa:1288|COL4A6, CXDELq22.3, DELXq22.3, DFNX6; collagen, type IV, alpha 6; K06237 collagen, type IV, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146);; Pathways in cancer (ko05200);; Small cell lung cancer (ko05222)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; C-terminal tandem repeated domain in type 4 procollagen	Collagen alpha-6(IV) chain (Precursor) GN=COL4A6 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	"PREDICTED: collagen alpha-6(IV) chain, partial [Sus scrofa]"
ENSG00000197566(ZNF624)	--	3.195384905	143	2.088425213	114	2.892240318	116	1.644629044	98	1.73971258	92	2.01593431	124	0.656489812	-0.568566833	normal	0.93181212	-0.325931517	normal	0.967228319	0.086828852	normal	0.554338352	-0.269058086	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:57547|ZNF624; zinc finger protein 624; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain"	Zinc finger protein 624 GN=ZNF624 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 624 isoform X1 [Galeopterus variegatus]
ENSG00000197568(HHLA3)	--	3.497265162	33	4.813445243	50	5.555185862	64	4.596964	41	4.232630949	41	5.845446936	60	0.977355507	0.270990044	normal	0.968888207	-0.297767666	normal	0.974834084	-0.098984715	normal	0.946746066	-0.069234473	normal	--	--	--	--	--	--	--	--	HERV-H LTR-associating protein 3 GN=HHLA3 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: HERV-H LTR-associating protein 3 [Galeopterus variegatus]
ENSG00000197576(HOXA4)	--	1.150536485	34	0.79325928	19	1.05697484	31	0.72015912	16	0.79954807	22	0.6082577	18	0.799279604	-1.04775717	normal	0.986964622	0.176978877	normal	0.943730882	-0.744379431	normal	0.413547487	-0.605286342	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09304|5.6671e-102|hsa:3201|HOXA4, HOX1, HOX1D; homeobox A4; K09304 homeobox protein HoxA/B/C/D4 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-A4 GN=HOXA4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-A4 [Lipotes vexillifer]
ENSG00000197580(BCO2)	--	0.294542396	10	0.456842604	10	0.217176901	11	0.25345494	11	0.816672446	21	0.365232704	14	--	--	--	0.952131659	0.948238886	normal	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (GO:0016702);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K10252|0|ptr:451548|BCO2, BCDO2; beta-carotene oxygenase 2; K10252 beta,beta-carotene 9',10'-dioxygenase [EC:1.13.11.71] (A)"	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Retinal pigment epithelial membrane protein	"Beta,beta-carotene 9',10'-oxygenase GN=BCO2 OS=Homo sapiens (Human) PE=1 SV=5"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: beta,beta-carotene 9',10'-oxygenase isoform X1 [Balaenoptera acutorostrata scammoni]"
ENSG00000197584(KCNMB2)	--	0	0	0.034539554	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: potassium ion transport (GO:0006813);; Molecular Function: calcium-activated potassium channel activity (GO:0015269);; Cellular Component: membrane (GO:0016020);; 	"K04938|1.13545e-175|ptr:460857|KCNMB2, KCNMB3; potassium large conductance calcium-activated channel, subfamily M, beta member 2; K04938 potassium large conductance calcium-activated channel subfamily M beta member 2 (A)"	cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Insulin secretion (ko04911)	--	--	"Calcium-activated potassium channel, beta subunit;; KCNMB2, ball and chain domain"	Calcium-activated potassium channel subunit beta-2 GN=KCNMB2 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: calcium-activated potassium channel subunit beta-2 isoform X1 [Bubalus bubalis]
ENSG00000197586(ENTPD6)	--	44.87358701	2171	44.37948408	2141	50.68481237	2367	47.57017154	2261	38.53872844	1951	47.75893927	2424	0.987608539	0.027749759	normal	0.979038141	-0.155382549	normal	0.988309058	0.026022121	normal	0.911558094	-0.030193284	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K01511|0|ptr:458146|ENTPD6; ectonucleoside triphosphate diphosphohydrolase 6 (putative); K01511 ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240)	[F]	Nucleotide transport and metabolism	GDA1/CD39 (nucleoside phosphatase) family	Ectonucleoside triphosphate diphosphohydrolase 6 GN=ENTPD6 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: ectonucleoside triphosphate diphosphohydrolase 6 [Galeopterus variegatus]
ENSG00000197587(DMBX1)	--	0.931664218	74	0.417053689	39	1.010698414	73	1.201174182	86	0.94138046	79	0.890088187	64	0.966941116	0.182462708	normal	0.234959303	0.970024005	normal	0.968715823	-0.193824429	normal	0.632646487	0.278600477	normal	[K]	Transcription	Molecular Function: DNA binding (GO:0003677);; 	--	--	[R]	General function prediction only	Homeobox domain;; OAR domain	Diencephalon/mesencephalon homeobox protein 1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: diencephalon/mesencephalon homeobox protein 1 isoform X1 [Pteropus alecto]
ENSG00000197594(ENPP1)	--	1.895852705	227	1.893127097	224	1.684202	196	1.242297	147	1.455435948	173	1.060804	126	0.218822081	-0.652176346	normal	0.83638698	-0.391139297	normal	0.321065404	-0.639516659	normal	0.053046176	-0.558457874	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: scavenger receptor activity (GO:0005044);; Biological Process: immune response (GO:0006955);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: polysaccharide binding (GO:0030247);; Molecular Function: metal ion binding (GO:0046872);; 	"K01513|0|hsa:5167|ENPP1, ARHR2, COLED, M6S1, NPP1, NPPS, PC-1, PCA1, PDNP1; ectonucleotide pyrophosphatase/phosphodiesterase 1 (EC:3.1.4.1 3.6.1.9); K01513 ectonucleotide pyrophosphatase/phosphodiesterase family member 1/3 [EC:3.1.4.1 3.6.1.9] (A)"	Purine metabolism (ko00230);; Starch and sucrose metabolism (ko00500);; Riboflavin metabolism (ko00740);; Nicotinate and nicotinamide metabolism (ko00760);; Pantothenate and CoA biosynthesis (ko00770)	[R]	General function prediction only	Type I phosphodiesterase / nucleotide pyrophosphatase;; Somatomedin B domain;; DNA/RNA non-specific endonuclease	Nucleotide pyrophosphatase GN=ENPP1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	ectonucleotide pyrophosphatase/phosphodiesterase family member 1 [Oryctolagus cuniculus] 
ENSG00000197599(CCDC154)	--	0.324638065	23	0.308726149	23	0.280592032	19	0.152830403	11	0.15276761	10	0.570988947	40	0.935554661	-0.996774489	normal	0.903405939	-1.109689264	normal	0.744533069	1.009215262	normal	0.959445541	-0.109172383	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4631)	Coiled-coil domain-containing protein 154 GN=CCDC154 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	"PREDICTED: coiled-coil domain-containing protein 154, partial [Ceratotherium simum simum]"
ENSG00000197601(FAR1)	--	35.06207	2442	36.04464	2475	36.80178	2618	33.96838	2509	32.0608	2246	33.85145	2275	0.98872296	0.00821191	normal	0.980242249	-0.161393583	normal	0.972638964	-0.210759278	normal	0.566161733	-0.121492664	normal	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	"K13356|0|hsa:84188|FAR1, MLSTD2, SDR10E1; fatty acyl CoA reductase 1 (EC:1.2.1.n2); K13356 fatty acyl-CoA reductase [EC:1.2.1.-] (A)"	Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Male sterility protein;; Male sterility protein;; NAD dependent epimerase/dehydratase family;; Polysaccharide biosynthesis protein	Fatty acyl-CoA reductase 1 GN=FAR1 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: fatty acyl-CoA reductase 1 isoform X4 [Oryctolagus cuniculus]
ENSG00000197603(C5orf42)	--	3.136289782	862	4.770418918	1117	3.473299534	933	3.969133128	1053	4.091853279	993	4.76689854	1226	0.933084724	0.257497599	normal	0.961645456	-0.190915786	normal	0.763596178	0.385172301	normal	0.5643595	0.147236277	normal	--	--	--	--	--	--	--	Joubert syndrome-associated	Uncharacterized protein C5orf42 GN=C5orf42 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C5orf42 homolog [Galeopterus variegatus]
ENSG00000197608(ZNF841)	--	6.385768795	491	5.950664185	458	4.692778035	446	5.71888441	510	6.653041807	509	7.532517219	645	0.971490014	0.023868675	normal	0.962221579	0.13048268	normal	0.302020237	0.522482758	normal	0.310724473	0.233793012	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:284371|ZNF841; zinc finger protein 841; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 841 GN=ZNF841 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 836 [Tupaia chinensis]
ENSG00000197614(MFAP5)	--	0	0	0	0	0	0	0.139642924	5	0.187471463	4	0.027990882	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: microfibril (GO:0001527);; 	--	--	--	--	Microfibril-associated glycoprotein (MAGP)	Microfibrillar-associated protein 5 (Precursor) GN=MFAP5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: microfibrillar-associated protein 5 isoform X1 [Panthera tigris altaica]
ENSG00000197619(ZNF615)	--	2.890598461	198	3.826717203	235	2.900809233	200	2.922034795	192	2.297026805	169	3.233052915	219	0.964963383	-0.074638178	normal	0.647824395	-0.493302468	normal	0.960973802	0.121759338	normal	0.713453307	-0.147181189	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:284370|ZNF615; zinc finger protein 615; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; zinc-finger"	Zinc finger protein 615 GN=ZNF615 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 615 isoform X1 [Galeopterus variegatus]
ENSG00000197620(CXorf40A)	--	9.03495692	224	8.346026262	208	8.57935314	209	12.0891397	286	11.0001948	273	10.83451	263	0.889485956	0.319739331	normal	0.845175807	0.368545655	normal	0.892036654	0.321192338	normal	0.233849107	0.337327322	normal	--	--	--	--	--	--	--	--	Protein CXorf40A GN=CXorf40A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein CXorf40A homolog [Ursus maritimus] 
ENSG00000197622(CDC42SE1)	--	24.5416582	1282	25.11645647	1327	24.10193625	1254	31.7238985	1661	34.22885415	1766	31.25129048	1628	0.864070463	0.342462134	normal	0.777977016	0.390503476	normal	0.817525076	0.367881481	normal	0.019564912	0.366703374	normal	--	--	--	--	--	--	--	--	CDC42 small effector protein 1 GN=CDC42SE1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: CDC42 small effector protein 1 isoform X1 [Capra hircus] 
ENSG00000197629(MPEG1)	--	0	0	0	0	0	0	0	0	0	0	0.0114035	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MAC/Perforin domain	Macrophage-expressed gene 1 protein (Precursor) GN=MPEG1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: macrophage-expressed gene 1 protein [Leptonychotes weddellii]
ENSG00000197632(SERPINB2)	--	0	0	0.062189803	2	0.030978628	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13963|0|hsa:5055|SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; K13963 serpin B (A)"	Amoebiasis (ko05146)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Plasminogen activator inhibitor 2 (Precursor) GN=SERPINB2 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	plasminogen activator inhibitor 2 [Oryctolagus cuniculus] 
ENSG00000197635(DPP4)	--	1.068762984	67	0.960621586	66	1.188606661	81	1.339272606	92	1.590618	109	1.306076272	90	0.91925671	0.418423613	normal	0.54986093	0.689944789	normal	0.968388815	0.141209541	normal	0.365423975	0.422619908	normal	[E]	Amino acid transport and metabolism	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01278|0|hsa:1803|DPP4, ADABP, ADCP2, CD26, DPPIV, TP103; dipeptidyl-peptidase 4 (EC:3.4.14.5); K01278 dipeptidyl-peptidase 4 [EC:3.4.14.5] (A)"	Protein digestion and absorption (ko04974)	[O]	"Posttranslational modification, protein turnover, chaperones"	Dipeptidyl peptidase IV (DPP IV) N-terminal region;; Prolyl oligopeptidase family;; Alpha/beta hydrolase family	Dipeptidyl peptidase 4 soluble form GN=DPP4 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: dipeptidyl peptidase 4 [Balaenoptera acutorostrata scammoni]
ENSG00000197646(PDCD1LG2)	--	0.100743	4	0.0766384	3	0.27769	10	1.25534	50	0.634337	25	0.422024	17	4.21E-07	3.19246482	up	0.029251932	2.537508905	normal	--	--	--	--	--	--	--	--	--	"K06708|6.58735e-177|hsa:80380|PDCD1LG2, B7DC, Btdc, CD273, PD-L2, PDCD1L2, PDL2, bA574F11.2; programmed cell death 1 ligand 2; K06708 programmed cell death 1 ligand 2 (A)"	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain	Programmed cell death 1 ligand 2 (Precursor) GN=PDCD1LG2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: programmed cell death 1 ligand 2 [Ceratotherium simum simum]
ENSG00000197653(DNAH10)	--	0.062503918	7	0.31973333	6	0.073516959	6	0.069382838	3	0.024581512	7	0.062402017	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: ATPase activity (GO:0016887);; Cellular Component: dynein complex (GO:0030286);; 	"K10408|0|hsa:196385|DNAH10; dynein, axonemal, heavy chain 10; K10408 dynein heavy chain, axonemal (A)"	Huntington's disease (ko05016)	[Z]	Cytoskeleton	"Dynein heavy chain and region D6 of dynein motor;; Dynein heavy chain, N-terminal region 2;; Hydrolytic ATP binding site of dynein motor region D1;; Dynein heavy chain, N-terminal region 1;; P-loop containing dynein motor region D4;; P-loop containing dynein motor region D3;; ATP-binding dynein motor region D5;; Microtubule-binding stalk of dynein motor;; AAA domain (dynein-related subfamily);; AAA domain;; ATPase family associated with various cellular activities (AAA)"	"Dynein heavy chain 10, axonemal GN=DNAH10 OS=Homo sapiens (Human) PE=1 SV=4"	Z	Cytoskeleton	"PREDICTED: dynein heavy chain 10, axonemal [Loxodonta africana]"
ENSG00000197694(SPTAN1)	--	34.77380026	6811	33.51166633	6675	37.60780258	7667	56.75580343	11153	44.013902	8833	46.3155291	9218	0.014208331	0.680539946	normal	0.912337309	0.382633538	normal	0.982643883	0.257453771	normal	0.006260404	0.443681051	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	K06114|0|mcf:101865529|uncharacterized LOC101865529; K06114 spectrin alpha (A)	--	[Z]	Cytoskeleton	Spectrin repeat;; Ca2+ insensitive EF hand;; SH3 domain;; Variant SH3 domain;; EF-hand domain pair;; EF hand;; EF-hand domain pair;; EF-hand domain;; EF hand;; Variant SH3 domain;; Bacterial SH3 domain	"Spectrin alpha chain, non-erythrocytic 1 GN=SPTAN1 OS=Homo sapiens (Human) PE=1 SV=3"	Z	Cytoskeleton	"PREDICTED: spectrin alpha chain, non-erythrocytic 1 isoform X2 [Bos taurus]"
ENSG00000197696(NMB)	--	21.28663	304	17.27499	258	18.81716	286	15.38221	226	11.05953	159	18.37545	269	0.670678787	-0.455897425	normal	0.082545543	-0.714382293	normal	0.963476922	-0.096175946	normal	0.161470421	-0.395491792	normal	--	--	Biological Process: neuropeptide signaling pathway (GO:0007218);; 	K05223|2.21161e-65|pon:100451235|NMB; neuromedin B; K05223 neuromedin B (A)	--	--	--	Bombesin-like peptide	Neuromedin-B (Precursor) GN=NMB OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: neuromedin-B isoform X1 [Galeopterus variegatus]
ENSG00000197702(PARVA)	--	11.35916269	1029	12.15217025	1132	14.58468987	1150	21.76667976	2111	19.28774972	1874	19.1693178	1844	3.22E-07	1.004782611	up	0.00593719	0.705081057	normal	0.010838012	0.672208936	normal	8.09E-09	0.794443473	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06275|0|cjc:100395254|PARVA; parvin, alpha; K06275 parvin (A)"	Focal adhesion (ko04510)	[Z]	Cytoskeleton	Calponin homology (CH) domain;; CAMSAP CH domain	Alpha-parvin GN=PARVA OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: alpha-parvin [Ceratotherium simum simum]
ENSG00000197705(KLHL14)	--	0	0	0	0	0	0	0.0129955	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K10451|0|pps:100990808|KLHL14; kelch-like family member 14; K10451 kelch-like protein 14 (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; BTB And C-terminal Kelch"	Kelch-like protein 14 GN=KLHL14 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 14 [Pteropus alecto]
ENSG00000197712(FAM114A1)	--	15.62676025	994	15.23967888	911	13.01759525	918	13.90586146	1000	21.04527545	1060	9.616465197	707	0.97933421	-0.022115939	normal	0.958802184	0.196811639	normal	0.758992433	-0.384351754	normal	0.895946735	-0.050997637	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF719)	Protein NOXP20 GN=FAM114A1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein NOXP20 [Ceratotherium simum simum]
ENSG00000197713(RPE)	--	55.96303208	1808	56.7045754	1960	58.48552545	1974	33.7465755	1158	35.16675101	1130	27.75261888	987	0.010409886	-0.672870731	normal	0.000270068	-0.8151181	normal	3.09E-07	-1.007177941	down	1.37E-09	-0.831627986	normal	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: racemase and epimerase activity, acting on carbohydrates and derivatives (GO:0016857);; "	"K01783|1.11754e-169|ptr:459912|RPE, rcRPE; ribulose-5-phosphate-3-epimerase; K01783 ribulose-phosphate 3-epimerase [EC:5.1.3.1] (A)"	Pentose phosphate pathway (ko00030);; Pentose and glucuronate interconversions (ko00040);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Ribulose-phosphate 3 epimerase family	Ribulose-phosphate 3-epimerase GN=RPE OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: ribulose-phosphate 3-epimerase isoform X1 [Ochotona princeps] 
ENSG00000197714(ZNF460)	--	1.256946949	131	1.585543728	148	1.504605416	142	0.793958062	75	0.937741024	97	1.197016029	123	0.147483883	-0.822514159	normal	0.514831794	-0.623042196	normal	0.952873276	-0.213083546	normal	0.141800915	-0.532802763	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:10794|ZNF460, HZF8, ZNF272; zinc finger protein 460; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zn-finger in ubiquitin-hydrolases and other protein"	Zinc finger protein 460 GN=ZNF460 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 543 [Leptonychotes weddellii]
ENSG00000197721(CR1L)	--	0	0	0	0	0	0	0	0	0	0	0.0335547	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Sushi domain (SCR repeat)	Complement component receptor 1-like protein (Precursor) GN=CR1L OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: uncharacterized protein LOC102486522 [Tupaia chinensis]
ENSG00000197724(PHF2)	--	8.785156156	910	8.313006479	938	8.904034047	965	7.483547821	758	7.987422823	799	7.254855935	806	0.90287495	-0.293956231	normal	0.934365772	-0.252377557	normal	0.925313817	-0.267581052	normal	0.140637459	-0.272405576	normal	--	--	--	"K11445|0|hsa:5253|PHF2, CENP-35, GRC5, JHDM1E; PHD finger protein 2; K11445 JmjC domain-containing histone demethylation protein 1D/E/F (A)"	--	[B]	Chromatin structure and dynamics	"JmjC domain, hydroxylase;; PHD-finger;; Cupin-like domain"	Lysine-specific demethylase PHF2 GN=PHF2 OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: LOW QUALITY PROTEIN: lysine-specific demethylase PHF2 [Camelus dromedarius]
ENSG00000197728(RPS26)	--	306.5474	2753	331.9347	2766	342.9	3051	475.0162	4288	423.5919	3777	351.1518	3331	0.056366839	0.608194049	normal	0.73612529	0.427812176	normal	0.98760321	0.118325585	normal	0.011347421	0.389383274	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02976|5.04456e-50|gga:100857770|RPS26; ribosomal protein S26; K02976 small subunit ribosomal protein S26e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S26e	40S ribosomal protein S26 GN=RPS26 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S26 [Sorex araneus]
ENSG00000197746(PSAP)	--	583.08116	31730	647.971427	36459	509.787987	28457	608.719496	33471	636.1335068	34349	840.68479	45890	0.998567095	0.04622969	normal	0.998274101	-0.107428859	normal	0.038575986	0.68107602	normal	0.513298746	0.213979531	normal	--	--	Biological Process: lipid metabolic process (GO:0006629);; 	"K12382|0|hsa:5660|PSAP, GLBA, SAP1; prosaposin; K12382 saposin (A)"	Lysosome (ko04142)	[IG]	Lipid transport and metabolism;; Carbohydrate transport and metabolism	"Saposin-like type B, region 1;; Saposin-like type B, region 2;; Saposin A-type domain"	Saposin-D (Precursor) GN=PSAP OS=Homo sapiens (Human) PE=1 SV=2	GI	Carbohydrate transport and metabolism;; Lipid transport and metabolism	PREDICTED: prosaposin isoform X8 [Galeopterus variegatus]
ENSG00000197747(S100A10)	--	354.7636745	3976	377.3606222	4523	396.5871894	4635	635.811352	7216	553.2990465	6069	423.2573986	4795	0.000113233	0.828808305	normal	0.851920566	0.402635674	normal	0.992856539	0.040656992	normal	0.095549484	0.438812389	normal	--	--	--	K17274|5.6249e-66|mcf:102144339|S100A10; S100 calcium binding protein A10; K17274 calpactin-1 light chain (A)	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A10 GN=S100A10 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: protein S100-A10-like isoform X1 [Physeter catodon]
ENSG00000197748(CFAP43)	--	0.288365916	8	0.168883687	4	0.094614927	1	0.094425301	2	0.286522123	10	0.258386888	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cilia- and flagella-associated protein 43 {ECO:0000312|HGNC:HGNC:26684} OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: WD repeat-containing protein 96 [Ceratotherium simum simum]
ENSG00000197753(LHFPL5)	--	0	0	0.0801875	3	0.0522754	1	0.0537145	2	0.0262911	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Lipoma HMGIC fusion partner-like protein	Tetraspan membrane protein of hair cell stereocilia GN=LHFPL5 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	tetraspan membrane protein of hair cell stereocilia [Bos taurus] 
ENSG00000197756(RPL37A)	--	1593.20284	8953	1710.094904	9491	1622.137563	9422	1317.483381	7635	1201.553819	6521	1089.120072	6452	0.981930254	-0.260526814	normal	0.249685476	-0.562784571	normal	0.253139948	-0.554470127	normal	0.00459894	-0.457023794	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02921|2.04911e-59|umr:103662778|RPL37A; ribosomal protein L37a; K02921 large subunit ribosomal protein L37Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L37ae protein family	60S ribosomal protein L37a GN=RPL37A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L37a-like [Dasypus novemcinctus]
ENSG00000197757(HOXC6)	--	5.4391304	158	4.9104143	140	4.97261567	141	7.8567384	232	7.330639397	228	6.76007701	204	0.589636279	0.519179203	normal	0.18068694	0.676402578	normal	0.630761899	0.519921394	normal	0.043807394	0.575341613	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K09306|1.64874e-150|rno:252885|Hoxc6; homeo box C6; K09306 homeobox protein HoxA/B/C6 (A)	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-C6 GN=HOXC6 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: homeobox protein Hox-C6 isoform X1 [Mustela putorius furo] 
ENSG00000197763(TXNRD3)	--	3.326237064	162	3.392133908	140	2.906388023	129	3.063728315	140	4.245963304	194	3.141917315	144	0.944621542	-0.238958633	normal	0.78961195	0.445102742	normal	0.961309033	0.148755024	normal	0.790243536	0.128135411	normal	[C]	Energy production and conversion	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00384|0|ptr:460662|TXNRD3; thioredoxin reductase 3 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9] (A)	Pyrimidine metabolism (ko00240);; Selenocompound metabolism (ko00450)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain;; Pyridine nucleotide-disulphide oxidoreductase;; Glutaredoxin;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain;; Thi4 family"	Thioredoxin reductase 3 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin reductase 3 [Odobenus rosmarus divergens]
ENSG00000197766(CFD)	--	45.2884	708	29.0633	441	31.93293	541	14.70111	227	20.49174	319	22.0774	323	2.22E-16	-1.665147633	down	0.508996008	-0.486677244	normal	0.006991521	-0.749643272	normal	0.005570095	-0.97969884	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K01334|4.12736e-167|hsa:1675|CFD, ADIPSIN, ADN, DF, PFD; complement factor D (adipsin) (EC:3.4.21.46); K01334 component factor D [EC:3.4.21.46] (A)"	Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150)	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Complement factor D (Precursor) GN=CFD OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: complement factor D [Orycteropus afer afer]
ENSG00000197768(STPG3)	--	0.059117123	1	0.0957966	2	0.057783355	0	0	0	0.0455457	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C9orf173 GN=C9orf173 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf173 homolog isoform X1 [Galeopterus variegatus]
ENSG00000197769(MAP1LC3C)	--	0.058617	1	0.57472	10	0	0	0.112381	2	0.171253	2	0.173251	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10435|2.53314e-103|hsa:440738|MAP1LC3C, ATG8J, LC3C; microtubule-associated protein 1 light chain 3 gamma; K10435 microtubule-associated protein 1 light chain (A)"	--	[Z]	Cytoskeleton	Autophagy protein Atg8 ubiquitin like;; Ubiquitin-like autophagy protein Apg12	Microtubule-associated proteins 1A/1B light chain 3C (Precursor) GN=MAP1LC3C OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: microtubule-associated proteins 1A/1B light chain 3C-like [Loxodonta africana]
ENSG00000197771(MCMBP)	--	36.917698	2037	37.63327109	2041	37.130744	2057	40.21854282	2240	41.4219117	2280	33.028038	1832	0.984361553	0.106144127	normal	0.981610886	0.138234141	normal	0.975696505	-0.175277103	normal	0.917098815	0.028446813	normal	--	--	--	--	--	[S]	Function unknown	Mini-chromosome maintenance replisome factor;; Putative alanine racemase	Mini-chromosome maintenance complex-binding protein GN=MCMBP OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	minichromosome maintenance complex binding protein [Canis lupus familiaris]
ENSG00000197774(EME2)	--	1.767799	134	2.169781	197	2.288537	169	2.676660094	255	2.420834	210	3.12957	204	0.005150971	0.889917614	normal	0.963919939	0.070244819	normal	0.932545648	0.26112478	normal	0.191462773	0.398109283	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: nuclease activity (GO:0004518);; 	"K10883|0|hsa:197342|EME2, SLX2B, gs125; essential meiotic structure-specific endonuclease subunit 2; K10883 crossover junction endonuclease EME2 (A)"	Fanconi anemia pathway (ko03460)	--	--	ERCC4 domain	Probable crossover junction endonuclease EME2 GN=EME2 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: probable crossover junction endonuclease EME2 isoform X4 [Bos taurus] 
ENSG00000197776(KLHDC1)	--	0.508655867	20	0.588605212	14	0.60326824	17	0.49651786	19	0.928536015	27	0.451937426	16	0.98912648	-0.097172714	normal	0.937424095	0.858358575	normal	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif;; Kelch motif;; Kelch motif"	Kelch domain-containing protein 1 GN=KLHDC1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: kelch domain-containing protein 1 [Loxodonta africana]
ENSG00000197779(ZNF81)	--	1.241452399	242	1.2504389	237	1.711571623	264	1.30790578	255	2.139402502	300	2.40941229	309	0.966337101	0.044383423	normal	0.889018561	0.316848305	normal	0.940890731	0.217624092	normal	0.538561272	0.197269707	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:347344|ZNF81, HFZ20, MRX45, dJ54B20.6; zinc finger protein 81; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; zinc-finger;; DNA directed RNA polymerase, 7 kDa subunit"	Zinc finger protein 81 GN=ZNF81 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 81 [Galeopterus variegatus]
ENSG00000197780(TAF13)	--	15.2006	219	16.4561	220	15.51122	207	16.849	245	15.07387	211	15.28783	223	0.959716151	0.130155031	normal	0.963209773	-0.081117649	normal	0.963123054	0.098428552	normal	0.913836245	0.050240363	normal	[K]	Transcription	Biological Process: transcription from RNA polymerase II promoter (GO:0006366);; 	"K03127|9.95425e-66|cfr:102508029|TAF13; TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa; K03127 transcription initiation factor TFIID subunit 13 (A)"	Basal transcription factors (ko03022);; Herpes simplex infection (ko05168)	[K]	Transcription	"Transcription initiation factor IID, 18kD subunit"	Transcription initiation factor TFIID subunit 13 GN=TAF13 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription initiation factor TFIID subunit 13 [Camelus ferus]
ENSG00000197782(ZNF780A)	--	16.59145518	849	19.15015046	977	18.14606332	949	16.03095626	747	18.60363798	898	20.5244037	940	0.949184749	-0.21507326	normal	0.969195859	-0.142838968	normal	0.978777095	-0.022003541	normal	0.591848458	-0.122751761	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; Probable zinc-binding domain"	Zinc finger protein 780A GN=ZNF780A OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 780B isoform X6 [Equus caballus]
ENSG00000197785(ATAD3A)	--	9.5242089	482	10.6341094	555	11.64127999	601	12.936624	658	12.61825827	638	8.505235506	435	0.676117335	0.417080357	normal	0.955301086	0.179186425	normal	0.493429728	-0.473235071	normal	0.895946735	0.057625764	normal	[R]	General function prediction only	Molecular Function: ATP binding (GO:0005524);; 	K17681|0|ggo:101147150|ATAD3A; LOW QUALITY PROTEIN: ATPase family AAA domain-containing protein 3A; K17681 ATPase family AAA domain-containing protein 3A/B (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF3523);; ATPase family associated with various cellular activities (AAA);; AAA domain;; Zonular occludens toxin (Zot)	ATPase family AAA domain-containing protein 3A GN=ATAD3A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	hypothetical protein PANDA_013778 [Ailuropoda melanoleuca]
ENSG00000197798(FAM118B)	--	6.175423011	224	5.880641432	220	5.87860378	212	7.560229921	288	7.717782921	281	5.603326982	215	0.880959107	0.329738889	normal	0.88148274	0.329630814	normal	0.966936916	0.011896683	normal	0.462812295	0.23509771	normal	--	--	--	--	--	--	--	SIR2-like domain	Protein FAM118B GN=FAM118B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM118B isoform X1 [Oryctolagus cuniculus] 
ENSG00000197808(ZNF461)	--	3.1648738	139	3.02494574	128	2.965301312	116	3.592151155	148	3.599393331	151	3.881260077	154	0.967102334	0.059047478	normal	0.94997238	0.214641264	normal	0.876949311	0.396019181	normal	0.612216551	0.220876286	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:746663|ZNF461; zinc finger protein 461; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 461 GN=ZNF461 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 461 isoform X2 [Galeopterus variegatus]
ENSG00000197816(CCDC180)	--	0.954030546	97	0.550222543	61	0.683107202	74	0.558832552	59	0.408408564	51	0.487761559	48	0.525988163	-0.733053806	normal	0.96537266	-0.272343616	normal	0.834467428	-0.6170066	normal	0.232238549	-0.576064774	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4455);; Domain of unknown function (DUF4456)	Coiled-coil domain-containing protein 180 GN=CCDC180 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 180 [Balaenoptera acutorostrata scammoni]
ENSG00000197818(SLC9A8)	--	8.545611	958	6.177063718	692	6.697412	748	6.670189	743	6.932402	768	7.911548903	884	0.725185252	-0.396770885	normal	0.967599836	0.128640776	normal	0.942868017	0.232284199	normal	0.959389613	-0.022581912	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K14724|0|hsa:23315|SLC9A8, NHE-8, NHE8; solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8; K14724 solute carrier family 9 (sodium/hydrogen exchanger), member 8 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 8 GN=SLC9A8 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 8 isoform X3 [Canis lupus familiaris]
ENSG00000197822(OCLN)	--	14.00237488	901	9.857014898	705	12.45140869	771	10.76935099	698	9.483214682	596	8.464185194	544	0.720399154	-0.398358113	normal	0.922580071	-0.263122781	normal	0.322214285	-0.51021802	normal	0.041039381	-0.392998625	normal	--	--	Cellular Component: membrane (GO:0016020);; 	"K06088|0|hsa:100506658|OCLN, BLCPMG, PPP1R115; occludin (EC:2.1.1.67); K06088 occludin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Pathogenic Escherichia coli infection (ko05130);; Hepatitis C (ko05160)	--	--	Occludin homology domain;; Membrane-associating domain	Occludin GN=OCLN OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: occludin isoform X1 [Vicugna pacos]
ENSG00000197826(C4orf22)	--	0	0	0.434708202	5	0	0	0	0	0.0698205	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4464)	Uncharacterized protein C4orf22 GN=C4orf22 OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: uncharacterized protein C4orf22 homolog isoform X1 [Myotis lucifugus]
ENSG00000197837(HIST4H4)	--	0.976038038	124	1.058181069	135	0.935104106	117	1.005775	83	1.422192	68	0.7955349	93	0.65601593	-0.600824136	normal	0.018842889	-0.994765681	normal	0.930046923	-0.334635039	normal	0.082084603	-0.644979703	normal	[B]	Chromatin structure and dynamics	"Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000197841(ZNF181)	--	8.379273273	309	10.53284312	359	6.303110411	290	7.03823019	227	5.879532593	242	10.78864356	317	0.621675858	-0.472990636	normal	0.23721022	-0.587368943	normal	0.961305768	0.119542082	normal	0.249129977	-0.305968055	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pon:100171725|ZNF181; zinc finger protein 181; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 181 GN=ZNF181 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 181-like isoform 1 [Ceratotherium simum simum]
ENSG00000197852(FAM212B)-2	--	1.227677931	160	1.391059721	182	1.481042731	193	1.296217051	169	1.401545955	136	2.488420062	177	0.96674124	0.04767363	normal	0.808326648	-0.437536579	normal	0.960403207	-0.132062001	normal	0.684497972	-0.171457892	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000197852(FAM212B)-3	--	0.0856333	2	0	0	0	0	0.0852903	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000197857(ZNF44)	--	0.475102	25	0.632797	31	0.429476	20	0.4173455	22	0.513725	24	0.524153	25	0.98624294	-0.202011869	normal	0.977293509	-0.370086032	normal	0.984687475	0.293736679	normal	0.921405102	-0.119581902	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:51710|ZNF44, GIOT-2, KOX7, ZNF, ZNF504, ZNF55, ZNF58; zinc finger protein 44; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 44 GN=ZNF44 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 709 [Galeopterus variegatus]
ENSG00000197858(GPAA1)	--	78.17045793	2404	69.349518	2217	75.11340405	2401	102.0619589	3175	98.97486624	3045	93.70836303	2921	0.855730449	0.370280949	normal	0.682824	0.436152078	normal	0.952713599	0.274378593	normal	0.021154505	0.359116177	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; Cellular Component: GPI-anchor transamidase complex (GO:0042765);; 	"K05289|0|hsa:8733|GPAA1, GAA1, hGAA1; glycosylphosphatidylinositol anchor attachment 1; K05289 glycosylphosphatidylinositol transamidase (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Gaa1-like, GPI transamidase component"	Glycosylphosphatidylinositol anchor attachment 1 protein GN=GPAA1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glycosylphosphatidylinositol anchor attachment 1 protein [Bubalus bubalis]
ENSG00000197860(SGTB)	--	6.283471239	497	6.292050553	483	6.559791	541	6.460573007	542	5.339935	430	5.519743087	394	0.967986542	0.093936614	normal	0.949827152	-0.188487186	normal	0.541032369	-0.464197331	normal	0.492373137	-0.177096476	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Plant specific mitochondrial import receptor subunit TOM20	Small glutamine-rich tetratricopeptide repeat-containing protein beta GN=SGTB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: small glutamine-rich tetratricopeptide repeat-containing protein beta isoform X1 [Sus scrofa]
ENSG00000197863(ZNF790)	--	0.406711199	20	0.408068021	18	0.45841183	21	0.346818	13	0.18151006	8	0.664728388	19	0.98129062	-0.595208085	normal	--	--	--	0.988239312	-0.141931572	normal	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:388536|ZNF790; zinc finger protein 790; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Probable zinc-binding domain;; Transposase zinc-ribbon domain;; XPA protein N-terminal;; Rad4 beta-hairpin domain 1"	Zinc finger protein 790 GN=ZNF790 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 790 [Galeopterus variegatus]
ENSG00000197872(FAM49A)	--	1.431278443	108	1.645283548	101	2.79678883	151	1.315005882	77	1.036995386	73	3.819886901	245	0.833869212	-0.510291037	normal	0.867591466	-0.481297666	normal	0.134546777	0.684509174	normal	0.950458395	0.116938726	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1394)	Protein FAM49A GN=FAM49A OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM49A [Echinops telfairi] 
ENSG00000197879(MYO1C)	--	107.9999265	10778	112.5167292	10807	111.6616094	11317	81.28054701	8070	86.95954829	8068	84.15276841	8175	0.782530905	-0.448207042	normal	0.813007013	-0.443037625	normal	0.675528486	-0.477416969	normal	0.005164243	-0.457510659	normal	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	"K10356|0|hsa:4641|MYO1C, MMI-beta, MMIb, NMI, myr2; myosin IC; K10356 myosin I (A)"	--	[Z]	Cytoskeleton	Myosin head (motor domain);; Myosin tail;; IQ calmodulin-binding motif	Unconventional myosin-Ic GN=MYO1C OS=Homo sapiens (Human) PE=1 SV=4	Z	Cytoskeleton	PREDICTED: unconventional myosin-Ic [Vicugna pacos]
ENSG00000197885(NKIRAS1)	--	6.578814034	204	8.188111	253	7.596532	232	7.655880686	233	8.18047738	246	8.562613004	267	0.955731418	0.159801828	normal	0.964522483	-0.061532606	normal	0.948456615	0.193248397	normal	0.820323892	0.093879287	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17197|5.3683e-126|ptr:460227|NKIRAS1; NFKB inhibitor interacting Ras-like 1; K17197 NF-kappa-B inhibitor-interacting Ras-like protein (A)	--	[T]	Signal transduction mechanisms	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain	NF-kappa-B inhibitor-interacting Ras-like protein 1 GN=NKIRAS1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: NF-kappa-B inhibitor-interacting Ras-like protein 1 isoform X1 [Equus caballus] 
ENSG00000197889(MEIG1)	--	0.389497069	2	0.129292	1	0.253230257	1	0.369075	3	0.128347	0	0.256594419	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Meiosis-expressed	Meiosis expressed gene 1 protein homolog GN=MEIG1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: meiosis expressed gene 1 protein homolog isoform X1 [Physeter catodon] 
ENSG00000197892(KIF13B)	--	5.650392	1062	5.3806889	1011	5.162495553	980	6.753246596	1268	7.260508999	1223	7.184125309	1350	0.95313899	0.224640996	normal	0.940038342	0.252870508	normal	0.532205088	0.453215978	normal	0.065663071	0.310143223	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K17914|0|hsa:23303|KIF13B, GAKIN; kinesin family member 13B; K17914 kinesin family member 13 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain;; Kinesin protein;; CAP-Gly domain;; Kinesin protein 1B;; FHA domain	Kinesin-like protein KIF13B GN=KIF13B OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIF13B-like [Elephantulus edwardii]
ENSG00000197893(NRAP)	--	0.007507385	1	0	0	0	0	0	0	0.007167664	0	0.007320608	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Nebulin repeat;; LIM domain	Nebulin-related-anchoring protein OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: nebulin-related-anchoring protein isoform X2 [Galeopterus variegatus]
ENSG00000197894(ADH5)	--	54.14474361	1932	51.90244264	1889	56.77487311	1962	56.84269435	2086	59.68112893	2144	56.43940715	2061	0.9851727	0.079750758	normal	0.978079293	0.1611345	normal	0.985893526	0.062680879	normal	0.651427802	0.100319491	normal	[C]	Energy production and conversion	Biological Process: oxidation-reduction process (GO:0055114);; 	"K00121|0|hsa:128|ADH5, ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR; alcohol dehydrogenase 5 (class III), chi polypeptide (EC:1.1.1.1 1.1.1.284); K00121 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase [EC:1.1.1.284 1.1.1.1] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Carbon metabolism (ko01200);; Degradation of aromatic compounds (ko01220);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Alcohol dehydrogenase GroES-like domain;; Zinc-binding dehydrogenase	Alcohol dehydrogenase class-3 OS=Homo sapiens (Human) PE=1 SV=4	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: alcohol dehydrogenase class-3 [Trichechus manatus latirostris]
ENSG00000197903(HIST1H2BK)	--	34.6789	88	23.8571	63	21.4461	59	14.206	41	18.5229	47	16.0631	43	0.045765773	-1.103785931	normal	0.94081907	-0.432065222	normal	0.944036136	-0.451071459	normal	0.149081162	-0.702156998	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|5.1729e-60|lve:103086798|histone H2B type 1-K-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-K GN=HIST1H2BK OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5-like [Bubalus bubalis]
ENSG00000197905(TEAD4)	--	15.15792984	835	15.86775197	864	15.77962509	878	19.42733976	1064	14.7534906	936	19.19031761	1008	0.880470409	0.318297906	normal	0.974207296	0.09389274	normal	0.960008173	0.190604729	normal	0.308734319	0.201759443	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09448|0|hsa:7004|TEAD4, EFTR-2, RTEF1, TCF13L1, TEF-3, TEF3, TEFR-1, hRTEF-1B; TEA domain family member 4; K09448 transcriptional enhancer factor (A)"	Hippo signaling pathway (ko04390)	[K]	Transcription	TEA/ATTS domain family	Transcriptional enhancer factor TEF-3 GN=TEAD4 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: transcriptional enhancer factor TEF-3 isoform X3 [Panthera tigris altaica]
ENSG00000197912(SPG7)	--	27.74271595	1662	25.64106754	1525	28.42970354	1760	21.9955672	1342	23.37712236	1400	23.36001433	1373	0.870170977	-0.339018406	normal	0.975616128	-0.144659194	normal	0.82566949	-0.366178056	normal	0.085086532	-0.286563415	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Molecular Function: ATP binding (GO:0005524);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; 	"K09552|0|hsa:6687|SPG7, CAR, CMAR, PGN, SPG5C; spastic paraplegia 7 (pure and complicated autosomal recessive); K09552 spastic paraplegia 7 [EC:3.4.24.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Peptidase family M41;; ATPase family associated with various cellular activities (AAA);; FtsH Extracellular;; AAA domain (dynein-related subfamily);; Holliday junction DNA helicase ruvB N-terminus	Paraplegin GN=SPG7 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: paraplegin isoform X1 [Equus przewalskii]
ENSG00000197915(HRNR)	--	0.398686	65	0.312468	52	0.386217	64	0.738072	121	0.78313	129	0.783219	130	0.157115417	0.850710908	normal	0.000706203	1.265243855	up	0.022510152	0.997212091	normal	0.002807005	1.04926437	up	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Hornerin GN=HRNR OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	hypothetical protein PAL_GLEAN10005518 [Pteropus alecto]
ENSG00000197919(IFNA1)	--	0.0814051	1	0	0	0.318376	3	0.636464	8	0.954059	11	0.559676	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: cytokine receptor binding (GO:0005126);; Cellular Component: extracellular region (GO:0005576);; Biological Process: defense response (GO:0006952);; 	"K05414|1.30587e-119|hsa:3447|IFNA13; interferon, alpha 13; K05414 interferon alpha (A)"	Cytokine-cytokine receptor interaction (ko04060);; Regulation of autophagy (ko04140);; PI3K-Akt signaling pathway (ko04151);; Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; Jak-STAT signaling pathway (ko04630);; Natural killer cell mediated cytotoxicity (ko04650);; Tuberculosis (ko05152);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Autoimmune thyroid disease (ko05320)	--	--	Interferon alpha/beta domain	Interferon alpha-1/13 (Precursor) GN=IFNA13 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: interferon alpha-1-like [Orcinus orca]
ENSG00000197930(ERO1A)	--	52.53696321	3955	54.63087077	4020	49.12093486	3536	54.56866491	4080	38.74077867	2920	49.88682017	3613	0.992166844	0.014053819	normal	0.518263952	-0.482439754	normal	0.991348852	0.022777901	normal	0.573699711	-0.139113137	normal	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	"Molecular Function: protein disulfide isomerase activity (GO:0003756);; Cellular Component: endoplasmic reticulum (GO:0005783);; Molecular Function: oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor (GO:0016671);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K10950|0|hsa:30001|ERO1L, ERO1-L, ERO1-L-alpha, ERO1-alpha, ERO1A, ERO1LA; ERO1-like (S. cerevisiae); K10950 ERO1-like protein alpha [EC:1.8.4.-] (A)"	Protein processing in endoplasmic reticulum (ko04141);; Vibrio cholerae infection (ko05110)	[OU]	"Posttranslational modification, protein turnover, chaperones;; Intracellular trafficking, secretion, and vesicular transport"	Endoplasmic Reticulum Oxidoreductin 1 (ERO1)	ERO1-like protein alpha (Precursor) GN=ERO1L OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ERO1-like protein alpha [Trichechus manatus latirostris]
ENSG00000197933(ZNF823)	--	1.280894048	64	1.805487319	82	1.43678028	71	1.083638171	53	1.577891974	80	1.885643256	96	0.96381955	-0.295113164	normal	0.971185401	-0.056004729	normal	0.91340462	0.419217847	normal	0.949960332	0.058122305	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:55552|ZNF823, HSZFP36; zinc finger protein 823; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 823 GN=ZNF823 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 709 [Galeopterus variegatus]
ENSG00000197935(ZNF311)	--	0.163438	10	0.244324	15	0.209936	12	0.243721	15	0.301804	18	0.17768	11	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:282890|ZNF311, zf31; zinc finger protein 311; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 311 GN=ZNF311 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 311 [Ceratotherium simum simum]
ENSG00000197943(PLCG2)	--	3.49964241	316	2.967960399	294	2.490362894	250	1.315218038	122	1.408044655	145	1.757137397	172	1.34E-08	-1.392551169	down	0.000167112	-1.033457599	down	0.485397927	-0.54382143	normal	2.80E-05	-0.990590645	normal	--	--	Molecular Function: phosphatidylinositol phospholipase C activity (GO:0004435);; Molecular Function: protein binding (GO:0005515);; Biological Process: lipid metabolic process (GO:0006629);; Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K05859|0|hsa:5336|PLCG2, APLAID, FCAS3, PLC-IV, PLC-gamma-2; phospholipase C, gamma 2 (phosphatidylinositol-specific) (EC:3.1.4.11); K05859 phosphatidylinositol phospholipase C, gamma-2 [EC:3.1.4.11] (A)"	Inositol phosphate metabolism (ko00562);; ErbB signaling pathway (ko04012);; Ras signaling pathway (ko04014);; Calcium signaling pathway (ko04020);; NF-kappa B signaling pathway (ko04064);; HIF-1 signaling pathway (ko04066);; Phosphatidylinositol signaling system (ko04070);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Platelet activation (ko04611);; Natural killer cell mediated cytotoxicity (ko04650);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Leukocyte transendothelial migration (ko04670);; Neurotrophin signaling pathway (ko04722);; Inflammatory mediator regulation of TRP channels (ko04750);; Thyroid hormone signaling pathway (ko04919);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Non-small cell lung cancer (ko05223)	[I]	Lipid transport and metabolism	"Phosphatidylinositol-specific phospholipase C, X domain;; SH2 domain;; Phosphatidylinositol-specific phospholipase C, Y domain;; SH3 domain;; C2 domain;; Variant SH3 domain;; PH domain;; Phosphoinositide-specific phospholipase C, efhand-like;; Variant SH3 domain"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 GN=PLCG2 OS=Homo sapiens (Human) PE=1 SV=4"	I	Lipid transport and metabolism	"PREDICTED: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 isoform X1 [Equus przewalskii] "
ENSG00000197948(FCHSD1)	--	5.84784564	352	4.142426922	301	3.459456903	290	4.086669156	233	3.608005935	288	2.9551734	232	0.14738113	-0.62271103	normal	0.963577491	-0.084686204	normal	0.881361121	-0.328301314	normal	0.184631676	-0.345868346	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Z]	Cytoskeleton	"Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; Fes/CIP4, and EFC/F-BAR homology domain"	FCH and double SH3 domains protein 1 GN=FCHSD1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: FCH and double SH3 domains protein 1 [Lipotes vexillifer]
ENSG00000197951(ZNF71)	--	4.90579497	425	4.6633445	466	4.306062	408	5.449461401	505	4.811977	432	4.997269037	461	0.941238634	0.217267066	normal	0.96151374	-0.130285928	normal	0.955393067	0.167322376	normal	0.789634621	0.084260494	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; Recombinase zinc beta ribbon domain"	Endothelial zinc finger protein induced by tumor necrosis factor alpha GN=ZNF71 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: endothelial zinc finger protein induced by tumor necrosis factor alpha isoform X1 [Galeopterus variegatus]
ENSG00000197956(S100A6)	--	1159.30368	9309	1415.86401	11849	1305.08255	10978	1291.74181	11052	989.98416	7961	1128.9632	9234	0.990077968	0.21674424	normal	0.152639406	-0.595076984	normal	0.984875281	-0.257840269	normal	0.428154063	-0.207965869	normal	--	--	--	--	--	--	--	S-100/ICaBP type calcium binding domain	Protein S100-A6 GN=S100A6 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein S100-A6 [Galeopterus variegatus] 
ENSG00000197958(RPL12)	--	1317.39812	10780	1095.78895	9083	1156.584042	9653	1214.53826	10508	1265.62305	10343	1096.400746	9137	0.996103996	-0.067691563	normal	0.992984577	0.165961451	normal	0.995348477	-0.087534168	normal	0.99959612	0.001295843	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02870|6.85789e-117|ssc:414416|RPL12; ribosomal protein L12; K02870 large subunit ribosomal protein L12e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein L11, N-terminal domain;; Ribosomal protein L11, RNA binding domain"	60S ribosomal protein L12 GN=RPL12 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L12 [Bubalus bubalis]
ENSG00000197959(DNM3)	--	1.030788501	61	0.86010399	54	1.057627893	40	0.828006475	55	1.385282623	110	1.49838489	84	0.973272616	-0.175550534	normal	0.058940887	0.985334208	normal	0.114294389	1.034526196	normal	0.220224069	0.663425203	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K01528|0|mcf:102135212|DNM3; dynamin 3; K01528 dynamin GTPase [EC:3.6.5.5] (A)	Endocytosis (ko04144);; Synaptic vesicle cycle (ko04721);; Endocrine and other factor-regulated calcium reabsorption (ko04961);; Bacterial invasion of epithelial cells (ko05100)	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Dynamin central region;; Dynamin family;; Dynamin GTPase effector domain;; PH domain	Dynamin-3 GN=DNM3 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: dynamin-3 isoform X3 [Elephantulus edwardii]
ENSG00000197961(ZNF121)	--	4.970427	477	5.1637793	595	4.671721	542	4.502507995	446	3.59344529	360	3.651406489	434	0.962896332	-0.127353467	normal	0.007569066	-0.743861751	normal	0.862243947	-0.327864739	normal	0.046913462	-0.401696152	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Transposase zinc-ribbon domain;; Zinc ribbon domain;; NTF2 fold immunity protein;; NifU-like N terminal domain"	Zinc finger protein 121 GN=ZNF121 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 426-like isoform X5 [Tupaia chinensis] 
ENSG00000197965(MPZL1)	--	59.36573645	3254	62.15081087	3421	63.903578	3340	70.509661	3889	68.46601577	3540	66.11858225	3528	0.975805366	0.226254903	normal	0.99086523	0.027892577	normal	0.990226747	0.070679875	normal	0.62291914	0.108171688	normal	--	--	--	K06770|5.35549e-142|pon:100456771|MPZL1; myelin protein zero-like 1; K06770 myelin protein zero (A)	Cell adhesion molecules (CAMs) (ko04514)	--	--	Immunoglobulin V-set domain	Myelin protein zero-like protein 1 (Precursor) GN=MPZL1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: myelin protein zero-like protein 1 isoform X1 [Lipotes vexillifer]
ENSG00000197969(VPS13A)	--	13.86610983	2604	13.51403768	2631	14.96947106	2607	14.75104627	2783	14.29606347	2758	13.78424394	2663	0.988474227	0.065042073	normal	0.988643278	0.046558512	normal	0.989130633	0.022357571	normal	0.87084398	0.043784209	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Protein of unknown function (DUF1162);; N-terminal region of Chorein, a TM vesicle-mediated sorter;; ATG C terminal domain"	Vacuolar protein sorting-associated protein 13A GN=VPS13A OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vacuolar protein sorting-associated protein 13A isoform 1 [Ceratotherium simum simum]
ENSG00000197971(MBP)	--	18.24026227	1374	21.17614662	1606	20.28163361	1421	11.92878882	931	8.969793742	749	16.24083758	1134	0.071849345	-0.591551978	normal	1.15E-08	-1.120277058	down	0.871586268	-0.33337931	normal	0.000409764	-0.666000218	normal	--	--	Molecular Function: structural constituent of myelin sheath (GO:0019911);; 	K17269|0|ggo:101137222|MBP; myelin basic protein isoform 1; K17269 myelin basic protein (A)	--	--	--	Myelin basic protein	Myelin basic protein GN=MBP OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: myelin basic protein S isoform 1 [Ceratotherium simum simum]
ENSG00000197976(AKAP17A)	--	20.65309605	1659	20.5566091	1676	18.649544	1525	14.391108	1127	16.201711	1262	15.07669529	1216	0.074703348	-0.587993375	normal	0.651551985	-0.430287716	normal	0.872886132	-0.334585055	normal	0.002656265	-0.452037474	normal	--	--	--	"K13169|0|hsa:8227|AKAP17A, 721P, AKAP-17A, CCDC133, CXYorf3, DXYS155E, PRKA17A, SFRS17A, XE7, XE7Y; A kinase (PRKA) anchor protein 17A; K13169 splicing factor, arginine/serine-rich 17 (A)"	--	[R]	General function prediction only	--	A-kinase anchor protein 17A GN=AKAP17A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: A-kinase anchor protein 17A isoform X1 [Canis lupus familiaris] 
ENSG00000197977(ELOVL2)	--	9.009882	536	8.66966	510	7.706008	449	7.180816	428	6.903471	413	6.225873672	371	0.82431685	-0.354315062	normal	0.867698171	-0.324709826	normal	0.906766724	-0.282539136	normal	0.138991798	-0.32460966	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K10205|0|ptr:750765|ELOVL2; ELOVL fatty acid elongase 2; K10205 elongation of very long chain fatty acids protein 2 [EC:2.3.1.199] (A)	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[I]	Lipid transport and metabolism	GNS1/SUR4 family	Elongation of very long chain fatty acids protein 2 GN=ELOVL2 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: elongation of very long chain fatty acids protein 2 [Odobenus rosmarus divergens]
ENSG00000197978(GOLGA6L9)	--	2.710437013	269	2.584321991	277	2.80294	269	2.617261547	280	2.577315614	285	2.8115883	330	0.967127375	0.026838144	normal	0.966373191	0.019544193	normal	0.909290566	0.285118863	normal	0.74863308	0.114349178	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 6-like protein 9 GN=GOLGA6L9 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000197980(LEKR1)	--	1.2950491	19	0.360114951	8	0.392850782	10	0.820953	17	0.472856847	7	0.403329947	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	"Leucine-, glutamate- and lysine-rich protein 1 GN=LEKR1 OS=Homo sapiens (Human) PE=2 SV=2"	S	Function unknown	"PREDICTED: leucine-, glutamate- and lysine-rich protein 1 [Camelus dromedarius]"
ENSG00000197982(C1orf122)	--	35.311055	640	39.215915	732	36.188201	703	40.66619	762	39.647652	733	34.775852	649	0.944927157	0.220401461	normal	0.975220698	-0.019416921	normal	0.967924558	-0.123321466	normal	0.940905081	0.025561019	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf122 GN=C1orf122 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C1orf122 homolog isoform X1 [Mustela putorius furo]
ENSG00000197991(RP11-310K10.1)	--	0.025281191	2	0	0	0	0	0	0	0.01226212	0	0.025090888	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156);; Cellular Component: membrane (GO:0016020);; 	"K16498|0|hsa:64881|PCDH20, PCDH13; protocadherin 20; K16498 protocadherin delta 1 (A)"	--	--	--	Cadherin domain;; Cadherin-like	Protocadherin-20 (Precursor) GN=PCDH20 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protocadherin-20-like [Leptonychotes weddellii]
ENSG00000197993(KEL)	--	0.03833117	2	0	0	0.093202246	4	0.019173218	1	0	0	0.034958953	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; 	"K06577|0|hsa:3792|KEL, CD238, ECE3; Kell blood group, metallo-endopeptidase (EC:3.4.24.-); K06577 Kell blood group glycoprotein [EC:3.4.24.-] (A)"	--	[E]	Amino acid transport and metabolism	Peptidase family M13;; Peptidase family M13	Kell blood group glycoprotein GN=KEL OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: kell blood group glycoprotein isoform X1 [Oryctolagus cuniculus]
ENSG00000198000(NOL8)	--	11.45037049	1055	12.6518984	1144	13.57077933	1187	12.73883749	1099	12.81517106	1141	12.83799345	1129	0.980116876	0.028076063	normal	0.980421558	-0.025181487	normal	0.978919896	-0.080460767	normal	0.923805752	-0.02823033	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[S]	Function unknown	"RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Nucleolar protein 8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: nucleolar protein 8 [Ceratotherium simum simum]
ENSG00000198001(IRAK4)	--	3.401501522	236	4.084882989	252	5.194092023	273	5.315889771	388	6.018757527	377	5.571140554	390	0.052353298	0.682937606	normal	0.317560228	0.556964607	normal	0.47068398	0.503934268	normal	0.007886521	0.580931652	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K04733|0|hsa:51135|IRAK4, IPD1, IRAK-4, NY-REN-64, REN64; interleukin-1 receptor-associated kinase 4 (EC:2.7.11.1); K04733 interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1] (A)"	NF-kappa B signaling pathway (ko04064);; Apoptosis (ko04210);; Toll-like receptor signaling pathway (ko04620);; Neurotrophin signaling pathway (ko04722);; Pertussis (ko05133);; Leishmaniasis (ko05140);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Tuberculosis (ko05152);; Measles (ko05162);; Influenza A (ko05164)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Interleukin-1 receptor-associated kinase 4 GN=IRAK4 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: interleukin-1 receptor-associated kinase 4 [Galeopterus variegatus]
ENSG00000198003(CCDC151)	--	0.3659235	17	0.282456	13	0.5790215	25	0.289789	14	0.162604	7	0.1798758	8	--	--	--	--	--	--	0.657213534	-1.486192822	normal	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 151 GN=CCDC151 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 151 isoform X1 [Galeopterus variegatus] 
ENSG00000198010(DLGAP2)	--	0	0	0	0	0.015557011	2	0.005273503	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: signaling (GO:0023052);; 	--	--	[T]	Signal transduction mechanisms	Guanylate-kinase-associated protein (GKAP) protein	Disks large-associated protein 2 GN=DLGAP2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: disks large-associated protein 2 isoform X1 [Sus scrofa]
ENSG00000198015(MRPL42)	--	42.85585398	997	36.93959596	902	46.0245407	1049	43.92600672	1133	44.38863305	1173	38.40058449	949	0.969785831	0.153428292	normal	0.829926176	0.357050847	normal	0.969068766	-0.152594733	normal	0.586683317	0.121480267	normal	--	--	--	"K17423|1.92584e-91|pon:100189839|MRPL42, DKFZP459F2016, MRPS32; mitochondrial ribosomal protein L42; K17423 large subunit ribosomal protein L42 (A)"	--	[S]	Function unknown	Mitochondrial 28S ribosomal protein S32	"39S ribosomal protein L42, mitochondrial (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L42, mitochondrial isoform X1 [Oryctolagus cuniculus]"
ENSG00000198018(ENTPD7)	--	3.073903651	338	3.789749	383	4.180034385	394	8.640509	866	7.742174741	797	6.01349297	598	4.04E-11	1.322622637	up	2.03E-06	1.032920768	up	0.122349048	0.591801673	normal	2.24E-05	0.99782463	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	"K14643|0|hsa:57089|ENTPD7, LALP1; ectonucleoside triphosphate diphosphohydrolase 7 (EC:3.6.1.-); K14643 ectonucleoside triphosphate diphosphohydrolase 7 [EC:3.6.1.-] (A)"	--	[F]	Nucleotide transport and metabolism	GDA1/CD39 (nucleoside phosphatase) family	Ectonucleoside triphosphate diphosphohydrolase 7 GN=ENTPD7 OS=Homo sapiens (Human) PE=2 SV=1	F	Nucleotide transport and metabolism	PREDICTED: ectonucleoside triphosphate diphosphohydrolase 7 [Ceratotherium simum simum]
ENSG00000198019(FCGR1B)	--	0	0	0.292814787	5	0	0	0	0	0.056406005	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06498|0|ggo:101150501|FCGR1B; high affinity immunoglobulin gamma Fc receptor IB isoform 1; K06498 high affinity immunoglobulin gamma Fc receptor I (A)	Phagosome (ko04145);; Osteoclast differentiation (ko04380);; Hematopoietic cell lineage (ko04640);; Fc gamma R-mediated phagocytosis (ko04666);; Leishmaniasis (ko05140);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain	High affinity immunoglobulin gamma Fc receptor IB (Precursor) GN=FCGR1B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	hypothetical protein PANDA_021726 [Ailuropoda melanoleuca]
ENSG00000198026(ZNF335)	--	5.85248	627	5.80433	629	5.10828	554	4.53735	486	6.09302	656	5.33682	572	0.731198081	-0.397232305	normal	0.973177219	0.039117147	normal	0.972449719	0.037736349	normal	0.719693589	-0.099456882	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc-finger domain"	Zinc finger protein 335 GN=ZNF335 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 335 isoform X1 [Equus caballus]
ENSG00000198028(ZNF560)	--	0	0	0	0	0	0	0	0	0	0	0.0195198	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:147741|ZNF560; zinc finger protein 560; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 560 GN=ZNF560 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 778-like [Galeopterus variegatus]
ENSG00000198034(RPS4X)	--	731.117143	16298	673.480069	15041	682.174	15260	779.039409	17577	766.620595	16929	780.1010004	17411	0.99727287	0.078154561	normal	0.995810044	0.149155568	normal	0.9949409	0.181935771	normal	0.579236144	0.134647702	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; 	"K02987|0|umr:103680191|RPS4X; ribosomal protein S4, X-linked; K02987 small subunit ribosomal protein S4e (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal family S4e;; RS4NT (NUC023) domain;; KOW motif;; S4 domain	"40S ribosomal protein S4, X isoform GN=RPS4X OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	Protein DBF4 like protein B [Pteropus alecto]
ENSG00000198039(ZNF273)	--	1.139559	64	1.618797663	98	1.664404	76	1.462417	67	1.421916	72	1.891323	96	0.975647309	0.034448655	normal	0.887346013	-0.457932618	normal	0.943832046	0.323012728	normal	0.967635723	-0.038617675	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:10793|ZNF273, HZF9; zinc finger protein 273; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; NTF2 fold immunity protein;; C1-like domain"	Zinc finger protein 273 GN=ZNF273 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000198040(ZNF84)	--	9.142057368	620	9.727221469	669	6.7822013	487	8.02809477	632	8.624651414	615	11.01519688	698	0.974121791	-0.003168145	normal	0.963780682	-0.142510238	normal	0.337022491	0.509684903	normal	0.679564134	0.109733238	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:452393|ZNF84; zinc finger protein 84; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 84 GN=ZNF84 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 84 isoform X1 [Galeopterus variegatus] 
ENSG00000198042(MAK16)	--	9.45905	668	8.51756	604	8.17063	569	9.40642	674	10.14224	713	8.36022	591	0.974776385	-0.017890809	normal	0.944999893	0.217425457	normal	0.972454031	0.046317242	normal	0.771144784	0.081870826	normal	[R]	General function prediction only	--	"K14831|1.08928e-171|hsa:84549|MAK16, MAK16L, RBM13; MAK16 homolog (S. cerevisiae); K14831 protein MAK16 (A)"	--	[A]	RNA processing and modification	Mak16 protein C-terminal region;; Ribosomal L28e protein family	Protein MAK16 homolog GN=MAK16 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: protein MAK16 homolog isoform X1 [Bos mutus]
ENSG00000198053(SIRPA)	--	10.531596	967	11.506599	1043	11.00860433	997	21.66351	1924	21.966602	1963	19.8012175	1790	1.78E-06	0.960586654	normal	2.83E-05	0.889938926	normal	0.000116444	0.835044188	normal	5.56E-11	0.895400606	normal	--	--	--	"K06551|0|hsa:140885|SIRPA, BIT, CD172A, MFR, MYD-1, P84, PTPNS1, SHPS1, SIRP; signal-regulatory protein alpha (EC:3.1.3.48); K06551 signal-regulatory protein alpha/beta1/gamma (A)"	Osteoclast differentiation (ko04380)	--	--	Immunoglobulin C1-set domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	Tyrosine-protein phosphatase non-receptor type substrate 1 (Precursor) GN=SIRPA OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type substrate 1 isoform X2 [Mustela putorius furo]
ENSG00000198054(DSCR8)	--	0	0	0	0	0	0	0.430299751	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Down syndrome critical region protein 8 GN=DSCR8 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	--
ENSG00000198055(GRK6)	--	17.53194402	843	15.50268605	793	17.2474968	868	13.42828341	642	13.72361422	668	14.53877834	696	0.64534344	-0.422905222	normal	0.921251382	-0.268340965	normal	0.866232245	-0.326263026	normal	0.059006659	-0.34073175	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08291|0|hsa:2870|GRK6, GPRK6; G protein-coupled receptor kinase 6 (EC:2.7.11.16); K08291 G protein-coupled receptor kinase [EC:2.7.11.16] (A)"	Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Regulator of G protein signaling domain	G protein-coupled receptor kinase 6 GN=GRK6 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G protein-coupled receptor kinase 6 isoform 1 [Ceratotherium simum simum]
ENSG00000198060(MARCH5)	--	19.473542	1062	17.5945996	969	18.15091713	979	22.102748	1219	21.523008	1173	18.51016528	1010	0.968292526	0.167855309	normal	0.938478628	0.253847352	normal	0.979054192	0.03662738	normal	0.457854539	0.154851868	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	K10660|0|aml:100463801|e3 ubiquitin-protein ligase MARCH5-like; K10660 E3 ubiquitin-protein ligase MARCH5 [EC:6.3.2.19] (A)	--	[S]	Function unknown	RING-variant domain	E3 ubiquitin-protein ligase MARCH5 GN=MARCH5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase MARCH5 isoform 2 [Dasypus novemcinctus]
ENSG00000198062(POTEH)	--	0	0	0	0	0	0	0.023844856	1	0	0	0.045306327	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17299|0|hsa:23784|POTEH, A26C3, ACTBL1, CT104.7, POTE22; POTE ankyrin domain family, member H; K17299 POTE ankyrin domain family protein (A)"	--	[Z]	Cytoskeleton	Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	POTE ankyrin domain family member H GN=POTEH OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: putative ankyrin repeat domain-containing protein 19 isoform X2 [Bos taurus]
ENSG00000198064(NPIPB13)	--	3.447899243	27	3.46624599	31	3.538442874	31	2.96801038	26	1.546473321	15	2.625689427	32	0.986219146	-0.080605348	normal	0.859716326	-0.997392282	normal	0.98419755	0.035793575	normal	0.723241561	-0.306534095	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Putative NPIP-like protein LOC613037 OS=Homo sapiens (Human) PE=5 SV=4	S	Function unknown	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000198074(AKR1B10)	--	148.366	4637	197.361	6189	141.3	4413	413.887	13068	461.137	14276	547.663	17104	0	1.463641038	up	1.71E-10	1.184191112	up	0	1.945845692	up	3.84E-12	1.523554242	up	[R]	General function prediction only	--	"K00011|0|hsa:57016|AKR1B10, AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI; aldo-keto reductase family 1, member B10 (aldose reductase) (EC:1.1.1.2); K00011 aldehyde reductase [EC:1.1.1.21] (A)"	Pentose and glucuronate interconversions (ko00040);; Fructose and mannose metabolism (ko00051);; Galactose metabolism (ko00052);; Glycerolipid metabolism (ko00561)	[R]	General function prediction only	Aldo/keto reductase family	Aldo-keto reductase family 1 member B10 GN=AKR1B10 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: aldo-keto reductase family 1 member B10 [Galeopterus variegatus]
ENSG00000198075(SULT1C4)	--	0.0617212	2	0.27632	9	0.0306426	0	0.122487	4	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K01025|0|hsa:27233|SULT1C4, SULT1C, SULT1C2; sulfotransferase family, cytosolic, 1C, member 4 (EC:2.8.2.-); K01025 [EC:2.8.2.-] (A)"	--	[R]	General function prediction only	Sulfotransferase domain	Sulfotransferase 1C4 GN=SULT1C4 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: sulfotransferase 1C4 [Galeopterus variegatus]
ENSG00000198081(ZBTB14)	--	6.796216891	323	5.30531095	291	5.845889847	246	3.954305421	222	4.337713484	222	4.308609381	258	0.310032326	-0.568523688	normal	0.779256002	-0.409441767	normal	0.965737377	0.060060748	normal	0.260887738	-0.313975805	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger and BTB domain-containing protein 14 GN=ZBTB14 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	Zinc finger protein 161 like protein [Tupaia chinensis]
ENSG00000198087(CD2AP)	--	18.30781866	1695	20.6963	1914	21.636615	1958	23.6178249	2219	21.26544	1961	19.874355	1848	0.854994141	0.357508185	normal	0.9861846	0.013561562	normal	0.984015477	-0.091634587	normal	0.679467194	0.093135793	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K13738|0|hsa:23607|CD2AP, CMS; CD2-associated protein; K13738 CD2-associated protein (A)"	Bacterial invasion of epithelial cells (ko05100)	[T]	Signal transduction mechanisms	Variant SH3 domain;; SH3 domain;; Variant SH3 domain	CD2-associated protein GN=CD2AP OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: CD2-associated protein isoform X1 [Equus przewalskii] 
ENSG00000198099(ADH4)	--	0.03217297	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	Biological Process: oxidation-reduction process (GO:0055114);; 	"K13980|0|hsa:127|ADH4, ADH-2, HEL-S-4; alcohol dehydrogenase 4 (class II), pi polypeptide (EC:1.1.1.1); K13980 alcohol dehydrogenase 4 [EC:1.1.1.1] (A)"	Glycolysis / Gluconeogenesis (ko00010);; Fatty acid degradation (ko00071);; Tyrosine metabolism (ko00350);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	Alcohol dehydrogenase 4 GN=ADH4 OS=Homo sapiens (Human) PE=1 SV=5	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: alcohol dehydrogenase 4 isoform X1 [Galeopterus variegatus]
ENSG00000198105(ZNF248)	--	4.566283046	352	4.835668555	419	6.890413713	430	4.049619486	324	4.075953624	340	4.930065021	411	0.957177219	-0.149732375	normal	0.874269308	-0.321551059	normal	0.967772377	-0.073226262	normal	0.519151941	-0.180216763	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:57209|ZNF248, bA162G10.3; zinc finger protein 248; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; TFIIH C1-like domain;; AN1-like Zinc finger"	Zinc finger protein 248 GN=ZNF248 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 248 isoform X2 [Galeopterus variegatus]
ENSG00000198108(CHSY3)	--	0.717939	35	1.001913	32	0.3907229	23	0.4307944	14	0.283813	12	0.1718444	11	0.559812692	-1.262338105	normal	0.556731486	-1.330162595	normal	0.938363885	-0.977694162	normal	0.036619772	-1.304953163	normal	--	--	"Molecular Function: acetylgalactosaminyltransferase activity (GO:0008376);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; Cellular Component: Golgi cisterna membrane (GO:0032580);; "	"K13499|0|hsa:337876|CHSY3, CHSY2, CSS3; chondroitin sulfate synthase 3 (EC:2.4.1.175 2.4.1.226); K13499 chondroitin sulfate synthase [EC:2.4.1.175 2.4.1.226] (A)"	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate (ko00532)	[G]	Carbohydrate transport and metabolism	Chondroitin N-acetylgalactosaminyltransferase;; Fringe-like;; N-terminal domain of galactosyltransferase;; Glycosyltransferase like family 2	Chondroitin sulfate synthase 3 GN=CHSY3 OS=Homo sapiens (Human) PE=2 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: chondroitin sulfate synthase 3 [Mustela putorius furo] 
ENSG00000198113(TOR4A)	--	27.1308	1860	30.9773	2185	27.8838	1992	28.614	1963	24.6697	1688	26.1317	1806	0.985856559	0.046887586	normal	0.786210021	-0.393434171	normal	0.979001819	-0.149591872	normal	0.386040822	-0.167286872	normal	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	[R]	General function prediction only	Torsin;; AAA domain;; AAA domain;; ATPase family associated with various cellular activities (AAA)	Torsin-4A GN=TOR4A OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: torsin-4A [Odobenus rosmarus divergens]
ENSG00000198121(LPAR1)	--	32.7088445	1422	31.8833592	1457	26.76804163	1187	21.19612498	977	18.8375006	862	27.13981949	1231	0.105489704	-0.571573344	normal	0.000974652	-0.777605614	normal	0.981092054	0.044164131	normal	0.058695877	-0.426254347	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04289|0|ptr:464655|LPAR1, EDG2; lysophosphatidic acid receptor 1; K04289 lysophosphatidic acid receptor 1 (A)"	Rap1 signaling pathway (ko04015);; Neuroactive ligand-receptor interaction (ko04080);; PI3K-Akt signaling pathway (ko04151);; Gap junction (ko04540);; Pathways in cancer (ko05200)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Lysophosphatidic acid receptor 1 GN=LPAR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: lysophosphatidic acid receptor 1 [Ceratotherium simum simum]
ENSG00000198125(MB)	--	4.231702882	67	5.606646874	76	2.988920598	44	5.02123432	72	5.954036911	82	4.155685705	56	0.974319849	0.071423451	normal	0.970680313	0.086539909	normal	0.964687326	0.32956944	normal	0.836981988	0.144776344	normal	--	--	Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; 	--	--	[C]	Energy production and conversion	Globin	Myoglobin GN=MB OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: myoglobin isoform X1 [Pteropus alecto] 
ENSG00000198130(HIBCH)	--	13.9527607	415	12.30037535	365	16.5178113	496	9.870726	304	11.6018991	344	9.124433793	275	0.538550052	-0.477796088	normal	0.962588686	-0.106460011	normal	0.000822273	-0.85564473	normal	0.02274069	-0.488139454	normal	[I]	Lipid transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	"K05605|0|hsa:26275|HIBCH, HIBYLCOAH; 3-hydroxyisobutyryl-CoA hydrolase (EC:3.1.2.4); K05605 3-hydroxyisobutyryl-CoA hydrolase [EC:3.1.2.4] (A)"	"Valine, leucine and isoleucine degradation (ko00280);; beta-Alanine metabolism (ko00410);; Propanoate metabolism (ko00640);; Carbon metabolism (ko01200)"	[I]	Lipid transport and metabolism	2-enoyl-CoA Hydratase C-terminal region;; Enoyl-CoA hydratase/isomerase family	"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (Precursor) GN=HIBCH OS=Homo sapiens (Human) PE=1 SV=2"	I	Lipid transport and metabolism	"PREDICTED: 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial isoform X1 [Lipotes vexillifer]"
ENSG00000198131(ZNF544)	--	14.30540821	479	10.7561957	372	14.54270595	435	15.13501776	490	14.46219219	468	12.30732206	443	0.971419255	0.001917748	normal	0.885259696	0.308658533	normal	0.970458398	0.017938059	normal	0.735547601	0.102167849	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:27300|ZNF544; zinc finger protein 544; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 544 GN=ZNF544 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 544 [Physeter catodon]
ENSG00000198133(TMEM229B)	--	0.238282814	18	0.147066429	10	0.130903216	8	0.599409659	32	1.122437813	58	0.627807429	26	0.942406682	0.750647444	normal	1.68E-05	2.350266419	up	0.589184255	1.52480743	normal	0.03777782	1.666015878	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1113)	Transmembrane protein 229B GN=TMEM229B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 229B [Sorex araneus]
ENSG00000198142(SOWAHC)	--	8.57047	661	7.57618	595	7.63677	596	4.40505	344	4.16943	322	4.17312	324	1.55E-05	-0.969889829	normal	0.000176431	-0.904080661	normal	0.000230381	-0.884518065	normal	1.20E-07	-0.925041858	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein SOWAHC GN=SOWAHC OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein SOWAHC [Felis catus]
ENSG00000198146(ZNF770)	--	20.67210092	1629	22.28943654	1745	21.67905615	1664	18.61149745	1443	16.99914896	1342	21.83296288	1728	0.965067361	-0.205541422	normal	0.752690887	-0.399872499	normal	0.984704877	0.046115213	normal	0.344499255	-0.179489689	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein 770 GN=ZNF770 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 770 [Ceratotherium simum simum]
ENSG00000198156(NPIPB6)	--	1.21245	30	0.945181	25	1.7426068	37	1.470229	34	0.7007427	15	2.359097	54	0.983372654	0.142864497	normal	0.963756966	-0.70295558	normal	0.936132012	0.519472608	normal	0.913593632	0.143701625	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B6 GN=NPIPB6 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000198157(HMGN5)	--	5.827809482	179	3.65086378	139	4.45776867	121	2.4464169	119	4.498718887	156	3.119750178	111	0.434425822	-0.613325117	normal	0.959591132	0.14355968	normal	0.964851363	-0.13102843	normal	0.64218322	-0.207243348	normal	--	--	Cellular Component: chromatin (GO:0000785);; Cellular Component: nucleus (GO:0005634);; Molecular Function: nucleosomal DNA binding (GO:0031492);; 	K17045|3.87216e-45|pps:100994196|HMGN5; high mobility group nucleosome binding domain 5; K17045 high-mobility group nucleosome-binding domain-containing protein 5 (A)	--	--	--	HMG14 and HMG17	High mobility group nucleosome-binding domain-containing protein 5 GN=HMGN5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: high mobility group nucleosome-binding domain-containing protein 5 [Trichechus manatus latirostris]
ENSG00000198160(MIER1)	--	9.238794	646	10.12222707	709	10.7557446	717	10.71895427	758	10.61165421	724	11.06783235	775	0.952338032	0.199393286	normal	0.975079445	0.008759024	normal	0.971444075	0.103721282	normal	0.69121974	0.102321982	normal	--	--	--	--	--	[R]	General function prediction only	ELM2 domain	Mesoderm induction early response protein 1 GN=MIER1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: mesoderm induction early response protein 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000198162(MAN1A2)	--	14.208711	1345	17.47953819	1634	15.08851014	1357	15.02726206	1460	15.85451	1509	16.09361161	1438	0.980739995	0.087434056	normal	0.977665977	-0.136110604	normal	0.981455731	0.075270017	normal	0.998125709	0.002016125	normal	--	--	"Molecular Function: mannosyl-oligosaccharide 1,2-alpha-mannosidase activity (GO:0004571);; Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Cellular Component: membrane (GO:0016020);; Biological Process: lipoprotein metabolic process (GO:0042157);; "	"K01230|0|hsa:10905|MAN1A2, MAN1B; mannosidase, alpha, class 1A, member 2 (EC:3.2.1.113); K01230 mannosyl-oligosaccharide alpha-1,2-mannosidase [EC:3.2.1.113] (A)"	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolase family 47	"Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB GN=MAN1A2 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: mannosyl-oligosaccharide 1,2-alpha-mannosidase IB [Tupaia chinensis]"
ENSG00000198168(SVIP)	--	9.5400912	424	9.180962	408	9.294519	410	12.093956	551	9.738255	431	9.786265	439	0.837162984	0.346053168	normal	0.967832972	0.057484842	normal	0.966528909	0.089984778	normal	0.516025214	0.172249035	normal	--	--	--	K14014|7.55662e-22|ggo:101126355|SVIP; small VCP/p97-interacting protein; K14014 small VCP/p97-interacting protein (A)	Protein processing in endoplasmic reticulum (ko04141)	--	--	--	Small VCP/p97-interacting protein GN=SVIP OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: small VCP/p97-interacting protein [Trichechus manatus latirostris]
ENSG00000198169(ZNF251)	--	6.648391	392	5.801530716	304	5.940749	372	6.402047506	341	5.153538	377	5.66158246	329	0.935026343	-0.230942663	normal	0.904600268	0.287779002	normal	0.950098431	-0.184707484	normal	0.898477272	-0.0497074	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:90987|ZNF251; zinc finger protein 251; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 251 GN=ZNF251 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: zinc finger protein 251 [Galeopterus variegatus]
ENSG00000198171(DDRGK1)	--	41.69019	1116	51.3008	1445	45.586	1287	50.1328	1387	49.25748	1321	62.38981	1700	0.923754993	0.282449143	normal	0.973966245	-0.150700559	normal	0.75929374	0.392828383	normal	0.519151941	0.175361503	normal	--	--	--	--	--	[S]	Function unknown	DDRGK domain	DDRGK domain-containing protein 1 (Precursor) GN=DDRGK1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: DDRGK domain-containing protein 1 [Camelus ferus]
ENSG00000198176(TFDP1)	--	35.53747021	1655	36.9814618	1709	38.609188	1782	50.17165501	2345	43.588106	2024	40.235663	1872	0.480563082	0.471555043	normal	0.964317707	0.222449281	normal	0.984931766	0.062739704	normal	0.131011901	0.256523792	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K04683|0|ptr:100608003|TFDP1; transcription factor Dp-1; K04683 transcription factor Dp-1 (A)	Cell cycle (ko04110);; TGF-beta signaling pathway (ko04350)	[K]	Transcription	Transcription factor DP;; E2F/DP family winged-helix DNA-binding domain	Transcription factor Dp-1 GN=TFDP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor Dp-1 isoform X2 [Galeopterus variegatus]
ENSG00000198178(CLEC4C)	--	0	0	0.080342355	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06723|1.87986e-158|hsa:170482|CLEC4C, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150; C-type lectin domain family 4, member C; K06723 C-type lectin domain family 4 member C (A)"	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 4 member C GN=UNQ9361/PRO34150 OS=Homo sapiens (Human) PE=1 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 4 member C [Tupaia chinensis]
ENSG00000198182(ZNF607)	--	4.189778082	335	4.551351157	373	4.312036	298	4.1059415	341	3.484618114	282	4.768357191	386	0.968457559	-0.005197991	normal	0.720626973	-0.42292794	normal	0.826371152	0.363372534	normal	0.974200785	-0.016923123	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:468858|ZNF607; zinc finger protein 607; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; NTF2 fold immunity protein;; Zinc-finger double-stranded RNA-binding;; TFIIH C1-like domain"	Zinc finger protein 607 GN=ZNF607 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 607 [Galeopterus variegatus]
ENSG00000198185(ZNF334)	--	0	0	0	0	0	0	0	0	0	0	0.017748062	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09228|0|mcc:706702|ZNF334; zinc finger protein 334; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 334 GN=ZNF334 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 334 isoform X1 [Loxodonta africana]
ENSG00000198189(HSD17B11)	--	38.315615	1026	40.133143	1069	37.09967303	980	34.84740847	918	37.827679	1001	36.56316628	969	0.96030083	-0.190994353	normal	0.974029406	-0.116076699	normal	0.97909636	-0.024538445	normal	0.629091647	-0.111635299	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; KR domain;; Enoyl-(Acyl carrier protein) reductase	Estradiol 17-beta-dehydrogenase 11 (Precursor) OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: estradiol 17-beta-dehydrogenase 11 [Tupaia chinensis] 
ENSG00000198198(SZT2)	--	3.85211541	1089	3.67252	959	3.923849	1050	3.199731	915	3.685063	1023	4.0809691	1183	0.917978704	-0.281558524	normal	0.977002553	0.071667435	normal	0.968879516	0.163547269	normal	0.978032831	-0.009667387	normal	--	--	--	--	--	--	--	--	Protein SZT2 GN=SZT2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein SZT2 isoform X1 [Panthera tigris altaica]
ENSG00000198203(SULT1C2)	--	0.273635513	13	0.712797988	35	0.272228764	15	1.689788889	97	2.010931293	114	4.571267972	236	6.68E-11	2.73201839	up	1.03E-05	1.640749773	up	0	3.838504854	up	0.005886643	2.807352626	up	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K01025|0|mcc:693398|SULT1C4, SULT1C1, SULT1C2; sulfotransferase 1C2-like; K01025 [EC:2.8.2.-] (A)"	--	[R]	General function prediction only	Sulfotransferase domain	Sulfotransferase 1C2 GN=SULT1C2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	hypothetical protein PANDA_020755 [Ailuropoda melanoleuca]
ENSG00000198205(ZXDA)	--	1.556921787	130	1.939863	157	1.59281	129	1.261999	101	1.643453247	137	1.54050316	129	0.897518331	-0.389746896	normal	0.948684181	-0.215788095	normal	0.968711882	-0.008195367	normal	0.660985852	-0.201427372	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger X-linked protein ZXDA GN=ZXDA OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger X-linked protein ZXDB-like [Leptonychotes weddellii]
ENSG00000198208(RPS6KL1)	--	0.019714563	1	0.01028472	1	0.378096436	3	0.64407115	20	0.28472238	12	0.250935325	9	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	--	--	[T]	Signal transduction mechanisms	Protein kinase domain;; MIT (microtubule interacting and transport) domain;; Protein tyrosine kinase	Ribosomal protein S6 kinase-like 1 GN=RPS6KL1 OS=Homo sapiens (Human) PE=2 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosomal protein S6 kinase-like 1 isoform X1 [Galeopterus variegatus]
ENSG00000198211(RP11-566K11.2)	--	128.9616562	4500	110.1754994	3983	138.7391153	4889	197.4468628	6675	143.1532676	4960	117.2158141	4182	0.283778424	0.537858919	normal	0.958622478	0.294957554	normal	0.978184333	-0.233559586	normal	0.566877831	0.219870717	normal	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K07375|0|pps:100980448|TUBB3; tubulin beta-3 chain; K07375 tubulin beta (A)	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx"	Tubulin beta-3 chain GN=TUBB3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	Tubulin beta-3 chain [Bos mutus]
ENSG00000198218(QRICH1)	--	17.175591	1254	16.791662	1222	17.956026	1215	18.971549	1116	15.449811	1146	15.642957	1164	0.96186102	-0.198774225	normal	0.976101743	-0.113918186	normal	0.979837493	-0.070067587	normal	0.552111028	-0.128568114	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF3504)	Glutamine-rich protein 1 GN=QRICH1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: glutamine-rich protein 1 isoform 1 [Dasypus novemcinctus] 
ENSG00000198223(CSF2RA)	--	9.883936987	345	9.127008601	331	9.98859489	293	7.914794764	292	8.00562327	237	13.55779944	506	0.916913996	-0.270150648	normal	0.530534017	-0.500653966	normal	0.004650624	0.776857122	normal	0.934015051	0.075298073	normal	--	--	--	"K05066|0|hsa:1438|CSF2RA, CD116, CDw116, CSF2R, CSF2RAX, CSF2RAY, CSF2RX, CSF2RY, GM-CSF-R-alpha, GMCSFR, GMR, SMDP4; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); K05066 granulocyte-macrophage colony-stimulating factor receptor alpha (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630);; Hematopoietic cell lineage (ko04640);; Pathways in cancer (ko05200)	--	--	"Interleukin-6 receptor alpha chain, binding;; Putative binding domain"	Granulocyte-macrophage colony-stimulating factor receptor subunit alpha (Precursor) GN=CSF2RA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	"hypothetical protein M91_13494, partial [Bos mutus]"
ENSG00000198225(FKBP1C)	--	0.183264	4	0.0903951	2	0.179722	3	0.270689	6	0.222609	4	0.36195	8	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K09568|4.1722e-72|mcf:102141598|peptidyl-prolyl cis-trans isomerase FKBP1A-like; K09568 FK506-binding protein 1 [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FKBP-type peptidyl-prolyl cis-trans isomerase	Peptidyl-prolyl cis-trans isomerase FKBP1A GN=FKBP1A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	peptidyl-prolyl cis-trans isomerase FKBP1A [Canis lupus familiaris] 
ENSG00000198231(DDX42)	--	56.96814073	4904	49.33613413	4258	51.1759466	4355	53.32035854	4522	56.64305103	4742	50.63095327	4300	0.989197295	-0.147782014	normal	0.989429688	0.133848094	normal	0.992508668	-0.026618199	normal	0.960928484	-0.016350139	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K12835|0|hsa:11325|DDX42, DDX42P, RHELP, RNAHP, SF3B8, SF3b125; DEAD (Asp-Glu-Ala-Asp) box helicase 42 (EC:3.6.4.13); K12835 ATP-dependent RNA helicase DDX42 [EC:3.6.4.13] (A)"	Spliceosome (ko03040)	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; SNF2 family N-terminal domain;; Type III restriction enzyme, res subunit"	ATP-dependent RNA helicase DDX42 GN=DDX42 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: ATP-dependent RNA helicase DDX42 [Ailuropoda melanoleuca]
ENSG00000198242(RPL23A)	--	818.0634643	16731	822.8450495	15806	801.6731887	16094	822.181095	16065	807.7210997	16111	824.5962145	16264	0.997084559	-0.089426578	normal	0.997350121	0.00614659	normal	0.997480895	0.006867099	normal	0.937561987	-0.026833242	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02893|2.49237e-86|oas:101123112|60S ribosomal protein L23a-like; K02893 large subunit ribosomal protein L23Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	"Ribosomal protein L23, N-terminal domain;; Ribosomal protein L23"	60S ribosomal protein L23a GN=RPL23A OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L23a-like [Ovis aries] 
ENSG00000198246(SLC29A3)	--	9.129369	361	7.153337	283	9.466678	379	7.39259	293	10.189355	400	10.421234	415	0.869001109	-0.330366356	normal	0.56873462	0.475623912	normal	0.962461865	0.122156102	normal	0.821676026	0.095385268	normal	--	--	Molecular Function: nucleoside transmembrane transporter activity (GO:0005337);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; 	"K15014|0|pps:100983531|SLC29A3; solute carrier family 29 (equilibrative nucleoside transporter), member 3; K15014 solute carrier family 29 (equilibrative nucleoside transporter), member 1/2/3 (A)"	--	[F]	Nucleotide transport and metabolism	Nucleoside transporter	Equilibrative nucleoside transporter 3 GN=SLC29A3 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: equilibrative nucleoside transporter 3 [Ceratotherium simum simum]
ENSG00000198252(STYX)	--	9.175099663	573	10.08904691	628	10.80172671	660	8.360233	526	7.287501	452	7.868993492	494	0.960328139	-0.153873777	normal	0.422401889	-0.494457994	normal	0.651471065	-0.425116433	normal	0.06731828	-0.359590029	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K18042|4.546e-167|ptr:743004|STYX; serine/threonine/tyrosine interacting protein; K18042 serine/threonine/tyrosine-interacting protein (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain"	Serine/threonine/tyrosine-interacting protein GN=STYX OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: serine/threonine/tyrosine-interacting protein [Orcinus orca] 
ENSG00000198258(UBL5)	--	175.1505084	579	225.1424063	776	180.6566671	632	228.6296039	838	208.6150055	689	200.416486	695	0.347851102	0.501443038	normal	0.954817495	-0.192580645	normal	0.966977595	0.128503658	normal	0.60784187	0.139254872	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K13113|2.2366e-47|mdo:100012958|ubiquitin-like protein 5-like; K13113 ubiquitin-like protein 5 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin family;; Ubiquitin-like domain	Ubiquitin-like protein 5 GN=UBL5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-like protein 5 isoform X1 [Physeter catodon]
ENSG00000198265(HELZ)	--	4.816775938	773	4.888873185	898	6.958874025	973	5.949022425	1142	4.943257704	903	6.62323801	1069	0.220064527	0.531316324	normal	0.977773136	-0.013393523	normal	0.973038012	0.127269922	normal	0.284170057	0.21479964	normal	[L]	"Replication, recombination and repair"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[A]	RNA processing and modification	"AAA domain;; AAA domain;; AAA domain;; Part of AAA domain;; Zinc finger C-x8-C-x5-C-x3-H type (and similar);; UvrD/REP helicase N-terminal domain;; PhoH-like protein;; Type III restriction enzyme, res subunit;; Ataxin-2 C-terminal region"	Probable helicase with zinc finger domain GN=HELZ OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: probable helicase with zinc finger domain [Galeopterus variegatus]
ENSG00000198270(TMEM116)	--	6.291912948	119	6.403334	117	7.141517023	126	4.692973306	83	4.096561041	75	4.969090326	94	0.770643724	-0.542179486	normal	0.577976498	-0.652351382	normal	0.878987415	-0.425054656	normal	0.164595847	-0.543308295	normal	--	--	--	--	--	[R]	General function prediction only	--	Transmembrane protein 116 GN=TMEM116 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 116 [Loxodonta africana]
ENSG00000198276(UCKL1)	--	16.814245	514	14.251897	445	14.12491767	468	13.8615209	443	14.80325	472	15.546979	464	0.929551131	-0.244505741	normal	0.968347832	0.063345927	normal	0.970967706	-0.020608287	normal	0.828952557	-0.070400653	normal	[F]	Nucleotide transport and metabolism	Molecular Function: ATP binding (GO:0005524);; Biological Process: metabolic process (GO:0008152);; Molecular Function: kinase activity (GO:0016301);; Molecular Function: transferase activity (GO:0016740);; 	K00876|0|pon:100445813|UCKL1; uridine-cytidine kinase 1-like 1; K00876 uridine kinase [EC:2.7.1.48] (A)	Pyrimidine metabolism (ko00240);; Drug metabolism - other enzymes (ko00983)	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Uracil phosphoribosyltransferase;; Phosphoribulokinase / Uridine kinase family;; AAA domain;; Chloramphenicol phosphotransferase-like protein;; AAA domain	Uridine-cytidine kinase-like 1 GN=UCKL1 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: uridine-cytidine kinase-like 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000198286(CARD11)	--	0	0	0.009192608	1	0.092434711	0	2.171487331	249	2.886536	313	2.008330049	194	0	7.334008774	up	0	6.953057709	up	0	7.010274298	up	1.64E-33	9.53726133	up	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	"K07367|0|pps:100980540|CARD11; caspase recruitment domain family, member 11; K07367 caspase recruitment domain-containing protein 11 (A)"	NF-kappa B signaling pathway (ko04064);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662)	--	--	Caspase recruitment domain;; Guanylate kinase	Caspase recruitment domain-containing protein 11 GN=CARD11 OS=Homo sapiens (Human) PE=1 SV=3	F	Nucleotide transport and metabolism	PREDICTED: caspase recruitment domain-containing protein 11 [Canis lupus familiaris]
ENSG00000198298(ZNF485)	--	1.805995609	67	2.001020027	75	1.969251989	73	1.702156451	64	1.310712556	48	1.63460449	61	0.97451462	-0.094699174	normal	0.793825684	-0.648792439	normal	0.963131738	-0.261445564	normal	0.558343771	-0.335006807	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger protein 485 GN=ZNF485 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 485 [Canis lupus familiaris]
ENSG00000198301(SDAD1)	--	7.78361	476	7.59047	458	8.212989055	493	8.116342702	498	8.056678276	492	7.94871222	487	0.970948988	0.034243842	normal	0.967443615	0.081624093	normal	0.971347083	-0.025877449	normal	0.942247793	0.028536914	normal	--	--	--	K14856|0|pps:100994501|SDAD1; SDA1 domain containing 1; K14856 protein SDA1 (A)	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	SDA1;; NUC130/3NT domain	Protein SDA1 homolog GN=SDAD1 OS=Homo sapiens (Human) PE=1 SV=3	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: protein SDA1 homolog isoform X2 [Equus caballus]
ENSG00000198315(ZKSCAN8)	--	6.641977349	790	7.198780998	853	6.7147757	781	5.976413287	720	6.092186857	720	7.540019119	896	0.962465512	-0.164353018	normal	0.924576994	-0.265462416	normal	0.958282331	0.189541839	normal	0.783253414	-0.07400581	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09229|0|hsa:7745|ZKSCAN8, LD5-1, ZNF192, ZSCAN40; zinc finger with KRAB and SCAN domains 8; K09229 KRAB and SCAN domains-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; SCAN domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; KRAB box;; Zinc ribbon domain"	Zinc finger protein with KRAB and SCAN domains 8 GN=ZKSCAN8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein with KRAB and SCAN domains 8 [Camelus bactrianus] 
ENSG00000198324(FAM109A)	--	3.384068882	183	2.909177	163	2.883324	154	6.075834548	320	6.75687924	367	5.408483077	226	0.018855483	0.770446142	normal	4.35E-06	1.142233258	up	0.537234908	0.540692315	normal	0.007676376	0.846533121	normal	--	--	--	--	--	--	--	PH domain;; Pleckstrin homology domain	Sesquipedalian-1 GN=FAM109A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sesquipedalian-1 [Trichechus manatus latirostris]
ENSG00000198326(TMEM239)	--	0.1445761	2	0.525901964	3	0.18371	0	0.249225565	2	0.720138298	3	0.442619239	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 239 GN=TMEM239 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane protein 239 [Camelus dromedarius]
ENSG00000198331(HYLS1)	--	7.336995	254	7.429962043	261	7.440371087	254	10.673105	373	8.763227449	304	7.9286	279	0.426923748	0.52090065	normal	0.945658822	0.197533639	normal	0.960168868	0.126426741	normal	0.281406756	0.291876304	normal	--	--	--	"K16472|0|hsa:219844|HYLS1, HLS; hydrolethalus syndrome 1; K16472 hydrolethalus syndrome protein 1 (A)"	--	--	--	Hydrolethalus syndrome protein 1 C-terminus	Hydrolethalus syndrome protein 1 GN=HYLS1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: hydrolethalus syndrome protein 1 isoform X1 [Equus caballus] 
ENSG00000198346(ZNF813)	--	0.47167	53	0.217193771	24	0.361060671	40	0.69195	78	0.633751584	58	0.602633638	69	0.896284917	0.514295006	normal	0.162393581	1.201476055	normal	0.712272981	0.75628474	normal	0.104923545	0.787640309	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:126017|ZNF813; zinc finger protein 813; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Prokaryotic RING finger family 1;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Protein of unknown function (DUF3895)"	Zinc finger protein 813 GN=ZNF813 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 347-like [Galeopterus variegatus]
ENSG00000198354(DCAF12L2)	--	0.581603	24	0.448061	19	0.184909	7	0.168167	7	0.257034	10	0.0955796	4	0.583873162	-1.607978949	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 12-like protein 2 GN=DCAF12L2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 12-like protein 2 [Sus scrofa]
ENSG00000198355(PIM3)	--	19.1005	647	20.1805	705	17.5432	622	14.1528	483	11.9908	407	19.2833	659	0.561945785	-0.451329299	normal	0.001140239	-0.811699142	normal	0.972011475	0.074895514	normal	0.182062839	-0.370251603	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	"Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	"K08807|0|hsa:415116|PIM3, pim-3; Pim-3 proto-oncogene, serine/threonine kinase (EC:2.7.11.1); K08807 proto-oncogene serine/threonine-protein kinase Pim-3 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Lipopolysaccharide kinase (Kdo/WaaP) family	Serine/threonine-protein kinase pim-3 GN=PIM3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase pim-3 [Odobenus rosmarus divergens]
ENSG00000198356(ASNA1)	--	38.04714912	949	45.01402615	1133	40.24914047	1017	38.89032795	959	38.35604126	940	44.35238268	1101	0.978910225	-0.015684276	normal	0.913332971	-0.290415475	normal	0.975812703	0.106051749	normal	0.793203414	-0.067714745	normal	[P]	Inorganic ion transport and metabolism	--	"K01551|0|umr:103682153|ASNA1; arsA arsenite transporter, ATP-binding, homolog 1 (bacterial); K01551 arsenite-transporting ATPase [EC:3.6.3.16] (A)"	--	[P]	Inorganic ion transport and metabolism	Anion-transporting ATPase;; CobQ/CobB/MinD/ParA nucleotide binding domain	ATPase ASNA1 {ECO:0000255|HAMAP-Rule:MF_03112} OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: ATPase ASNA1 [Condylura cristata]
ENSG00000198363(ASPH)	--	477.9136429	29452	519.182534	31614	473.1956538	28637	470.5228276	29573	344.6228627	22029	337.65255	20951	0.998490307	-0.02491597	normal	0.565957641	-0.542554863	normal	0.861602106	-0.459124234	normal	0.107403831	-0.32859051	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; Cellular Component: membrane (GO:0016020);; Biological Process: peptidyl-amino acid modification (GO:0018193);; 	"K00476|0|hsa:444|ASPH, AAH, BAH, CASQ2BP1, FDLAB, HAAH, JCTN, junctin; aspartate beta-hydroxylase (EC:1.14.11.16); K00476 aspartate beta-hydroxylase [EC:1.14.11.16] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Aspartyl beta-hydroxylase N-terminal region;; Aspartyl/Asparaginyl beta-hydroxylase;; TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Aspartyl/asparaginyl beta-hydroxylase GN=ASPH OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: aspartyl/asparaginyl beta-hydroxylase isoform X3 [Tupaia chinensis]
ENSG00000198369(SPRED2)	--	26.515152	1210	24.27081358	1259	24.379878	1111	14.49981708	841	18.61409931	965	17.51400912	906	0.14734603	-0.554811389	normal	0.721378341	-0.404547144	normal	0.900485843	-0.302111086	normal	0.007761225	-0.421710742	normal	--	--	Biological Process: multicellular organismal development (GO:0007275);; Biological Process: regulation of signal transduction (GO:0009966);; Cellular Component: membrane (GO:0016020);; 	"K04703|0|pps:100986414|SPRED2; sprouty-related, EVH1 domain containing 2; K04703 sprouty-related, EVH1 domain-containing protein (A)"	Jak-STAT signaling pathway (ko04630)	[T]	Signal transduction mechanisms	Sprouty protein (Spry);; WH1 domain	"Sprouty-related, EVH1 domain-containing protein 2 GN=SPRED2 OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: sprouty-related, EVH1 domain-containing protein 2 [Camelus ferus]"
ENSG00000198373(WWP2)	--	11.05876276	904	10.49029456	853	11.57689066	923	11.25424878	978	14.05735834	1227	13.56415513	1142	0.976105364	0.082544534	normal	0.346847499	0.502344733	normal	0.904743123	0.29842829	normal	0.085086532	0.300075672	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	K05630|0|pps:100973972|WWP2; WW domain containing E3 ubiquitin protein ligase 2; K05630 atrophin-1 interacting protein 2 (WW domain containing E3 ubiquitin protein ligase 2) [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain	NEDD4-like E3 ubiquitin-protein ligase WWP2 GN=WWP2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: NEDD4-like E3 ubiquitin-protein ligase WWP2 isoform X1 [Galeopterus variegatus]
ENSG00000198380(GFPT1)	--	13.972868	1841	14.654735	1933	15.528914	2006	15.37905	2049	13.71133	1803	15.0964777	1986	0.981962334	0.123500369	normal	0.981331701	-0.12177013	normal	0.986737032	-0.022730203	normal	0.98564369	-0.006833122	normal	[M]	Cell wall/membrane/envelope biogenesis	Molecular Function: carbohydrate derivative binding (GO:0097367);; Biological Process: carbohydrate derivative metabolic process (GO:1901135);; 	K00820|0|ptr:450203|GFPT1; glutamine--fructose-6-phosphate transaminase 1; K00820 glucosamine--fructose-6-phosphate aminotransferase (isomerizing) [EC:2.6.1.16] (A)	"Alanine, aspartate and glutamate metabolism (ko00250);; Amino sugar and nucleotide sugar metabolism (ko00520)"	[M]	Cell wall/membrane/envelope biogenesis	SIS domain;; Glutamine amidotransferases class-II;; Glutamine amidotransferase domain;; Glutamine amidotransferase domain;; Glutamine amidotransferases class-II	Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 GN=GFPT1 OS=Homo sapiens (Human) PE=1 SV=3	M	Cell wall/membrane/envelope biogenesis	PREDICTED: glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 isoform X1 [Bubalus bubalis]
ENSG00000198382(UVRAG)	--	7.161924736	516	9.074193027	641	8.764460629	600	6.5928901	472	6.937046507	477	7.091605291	513	0.958171678	-0.158921466	normal	0.594258373	-0.446535556	normal	0.936374953	-0.23365751	normal	0.175766349	-0.286093332	normal	--	--	Biological Process: positive regulation of autophagy (GO:0010508);; 	--	--	[R]	General function prediction only	UV radiation resistance protein and autophagy-related subunit 14;; C2 domain	UV radiation resistance-associated gene protein GN=UVRAG OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"PREDICTED: UV radiation resistance-associated gene protein, partial [Equus przewalskii]"
ENSG00000198393(ZNF26)	--	3.337729843	281	2.501819392	254	4.990945045	275	3.332514188	278	4.275515799	338	5.458466932	283	0.966601415	-0.046064284	normal	0.799235254	0.388755683	normal	0.967104073	0.032900637	normal	0.709757778	0.129431814	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|nle:100605202|ZNF26; zinc finger protein 26; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; TFIIH C1-like domain"	Zinc finger protein 26 GN=ZNF26 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 26 [Galeopterus variegatus]
ENSG00000198399(ITSN2)	--	11.851367	1517	13.1696087	1650	13.0614677	1581	9.346414007	1140	7.29021279	932	9.315422013	1198	0.578932132	-0.44250052	normal	0.000129022	-0.844446177	normal	0.709447145	-0.408051019	normal	0.00012318	-0.559179961	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; RhoGEF domain;; Cytoskeletal-regulatory complex EF hand;; C2 domain;; EF-hand domain pair;; EF hand;; EF-hand domain	Intersectin-2 GN=ITSN2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	hypothetical protein PANDA_001702 [Ailuropoda melanoleuca]
ENSG00000198400(NTRK1)	--	0.1055113	5	0.0196274	1	0.019556311	0	0	0	0.02006017	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K03176|0|pon:100452269|NTRK1; neurotrophic tyrosine kinase, receptor, type 1; K03176 neurotrophic tyrosine kinase receptor type 1 [EC:2.7.10.1] (A)"	MAPK signaling pathway (ko04010);; Endocytosis (ko04144);; Apoptosis (ko04210);; Neurotrophin signaling pathway (ko04722);; Inflammatory mediator regulation of TRP channels (ko04750);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Thyroid cancer (ko05216);; Central carbon metabolism in cancer (ko05230)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Protein tyrosine kinase;; Protein kinase domain;; Immunoglobulin I-set domain;; Leucine rich repeat;; Immunoglobulin domain	High affinity nerve growth factor receptor (Precursor) GN=NTRK1 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: high affinity nerve growth factor receptor isoform 2 [Orcinus orca]
ENSG00000198408(MGEA5)	--	41.372134	3761	41.84108918	3764	38.36637814	3441	43.49798553	3968	47.177862	4262	48.739364	4419	0.991592789	0.046444983	normal	0.986759433	0.157777806	normal	0.905452469	0.352463565	normal	0.332686849	0.1849787	normal	--	--	--	K15719|0|pon:100459796|MGEA5; meningioma expressed antigen 5 (hyaluronidase); K15719 protein O-GlcNAcase / histone acetyltransferase [EC:3.2.1.169 2.3.1.48] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	beta-N-acetylglucosaminidase	"Protein O-GlcNAcase {ECO:0000303|PubMed:11148210, ECO:0000303|PubMed:11788610} GN=MGEA5 OS=Homo sapiens (Human) PE=1 SV=2"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein O-GlcNAcase [Camelus bactrianus] 
ENSG00000198417(MT1F)	--	4.52289	34	3.31991	26	2.49691	19	6.169120244	47	10.32787	72	4.704066	31	0.963114655	0.420091023	normal	0.010247491	1.39729204	normal	0.957468563	0.656703707	normal	0.200293067	0.902520306	normal	--	--	--	K14739|1.81162e-07|pon:100435295|metallothionein-1F; K14739 metallothionein 1/2 (A)	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Metallothionein	Metallothionein-1F GN=MT1F OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	hypothetical protein CB1_001402132 [Camelus ferus]
ENSG00000198420(TCAF1)	--	23.34392398	2392	22.10742434	2400	19.09881216	2315	25.29487065	2605	29.31130265	2753	20.7810755	2383	0.986738796	0.092176976	normal	0.979459375	0.176439778	normal	0.98803806	0.033453776	normal	0.642689264	0.101819841	normal	--	--	--	--	--	--	--	Peptidase M60-like family	Protein FAM115A GN=FAM115A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM115A-like isoform X2 [Canis lupus familiaris] 
ENSG00000198431(TXNRD1)	--	556.7576004	34463	733.7635262	46213	607.6414871	37509	436.0434332	27071	364.9427437	22281	571.2175266	35304	0.969322855	-0.379113251	normal	4.20E-08	-1.073859537	down	0.998457609	-0.095692613	normal	0.098007254	-0.502004185	normal	[C]	Energy production and conversion	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: cell redox homeostasis (GO:0045454);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00384|0|hsa:7296|TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR; thioredoxin reductase 1 (EC:1.8.1.9); K00384 thioredoxin reductase (NADPH) [EC:1.8.1.9] (A)"	Pyrimidine metabolism (ko00240);; Selenocompound metabolism (ko00450)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain;; Pyridine nucleotide-disulphide oxidoreductase;; Pyridine nucleotide-disulphide oxidoreductase;; FAD binding domain;; Glutaredoxin;; Thi4 family"	"Thioredoxin reductase 1, cytoplasmic GN=TXNRD1 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: thioredoxin reductase 1, cytoplasmic isoform X2 [Tupaia chinensis]"
ENSG00000198435(NRARP)	--	3.835738	130	2.76129	94	2.838497989	107	2.69063	89	2.9615	92	1.446668	41	0.695218171	-0.569282439	normal	0.969702509	-0.051614077	normal	0.000703872	-1.359992796	down	0.168407679	-0.599270222	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Notch-regulated ankyrin repeat-containing protein GN=NRARP OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: notch-regulated ankyrin repeat-containing protein [Elephantulus edwardii]
ENSG00000198440(ZNF583)	--	1.553659472	68	1.32126413	85	1.381381638	81	1.146848433	63	1.12830083	64	1.391021342	70	0.972994698	-0.137779783	normal	0.919814439	-0.422131511	normal	0.964979777	-0.214545612	normal	0.640130864	-0.26913323	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:147949|ZNF583; zinc finger protein 583; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 583 GN=ZNF583 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 583 isoform 2 [Ceratotherium simum simum]
ENSG00000198443(KRTAP4-1)	--	1.346568494	22	0.975548248	14	1.391128733	16	0.379874118	7	0.564713771	4	0.997635646	9	0.758230056	-1.490238979	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	"Keratin, high sulfur B2 protein;; Keratin, high sulfur B2 protein"	Keratin-associated protein 4-1 GN=KRTAP4-1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: keratin-associated protein 4-1 [Bos taurus] 
ENSG00000198453(ZNF568)	--	1.726015082	90	1.467576764	93	2.749109282	105	0.779979403	47	1.221234535	57	0.889354152	56	0.172333111	-0.945362901	normal	0.592445602	-0.712740528	normal	0.155513948	-0.897201306	normal	0.0318767	-0.868369515	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|ptr:455979|ZNF568, ZNF420, ZNF91; zinc finger protein 568; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain"	Zinc finger protein 568 GN=ZNF568 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 568-like isoform X1 [Mustela putorius furo] 
ENSG00000198455(ZXDB)	--	5.76929	488	7.43303	630	5.70173	481	6.07675	516	6.2118	525	6.8048	578	0.970674191	0.049506073	normal	0.90671158	-0.283713736	normal	0.924406461	0.256005939	normal	0.998020245	-0.003238589	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Zinc finger X-linked protein ZXDB GN=ZXDB OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger X-linked protein ZXDB-like [Odobenus rosmarus divergens] 
ENSG00000198464(ZNF480)	--	15.23217999	579	13.9247092	674	13.21191225	534	17.23735242	636	16.82417433	560	14.75082733	641	0.968704219	0.104366857	normal	0.904045409	-0.288038139	normal	0.926298917	0.254534389	normal	0.962905538	0.018277223	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:456262|ZNF480; zinc finger protein 480; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; XPA protein N-terminal;; Transposase zinc-ribbon domain;; C1-like domain"	Zinc finger protein 480 GN=ZNF480 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 160-like isoform X3 [Galeopterus variegatus]
ENSG00000198467(TPM2)	--	156.74011	4474	172.996798	5198	165.0347372	4907	220.1297537	6243	202.7091705	5489	149.1411312	4312	0.70115322	0.449710681	normal	0.99310677	0.057143968	normal	0.984653203	-0.194711473	normal	0.702919039	0.115868431	normal	--	--	--	K10374|3.52665e-93|pps:100988547|TPM2; tropomyosin 2 (beta); K10374 tropomyosin 2 (A)	Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Dilated cardiomyopathy (ko05414)	[Z]	Cytoskeleton	Tropomyosin;; Tropomyosin like	Tropomyosin beta chain GN=TPM2 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: tropomyosin beta chain isoform X4 [Chrysochloris asiatica]
ENSG00000198471(RTP2)	--	0	0	0	0	0	0	0.0467986	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc-binding domain	Receptor-transporting protein 2 GN=RTP2 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: receptor-transporting protein 2 [Capra hircus]
ENSG00000198478(SH3BGRL2)	--	2.273810164	158	2.4945437	146	2.353906415	152	2.200226	138	1.732783382	123	2.023701206	124	0.948595248	-0.223758062	normal	0.938932456	-0.265733618	normal	0.929221727	-0.298726176	normal	0.520594041	-0.265707779	normal	--	--	Molecular Function: electron carrier activity (GO:0009055);; Molecular Function: protein disulfide oxidoreductase activity (GO:0015035);; Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[S]	Function unknown	"SH3-binding, glutamic acid-rich protein;; Glutaredoxin"	SH3 domain-binding glutamic acid-rich-like protein 2 GN=SH3BGRL2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: SH3 domain-binding glutamic acid-rich-like protein 2-like isoform 2 [Dasypus novemcinctus]
ENSG00000198483(ANKRD35)	--	0	0	0	0	0	0	0.083398909	6	0.013663452	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 35 GN=ANKRD35 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 35 [Condylura cristata]
ENSG00000198488(B3GNT6)	--	0.024118011	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K00739|0|hsa:192134|B3GNT6, B3Gn-T6, BGnT-6, beta-1,3-Gn-T6, beta3Gn-T6; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase) (EC:2.4.1.149); K00739 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase [EC:2.4.1.147] (A)"	Mucin type O-Glycan biosynthesis (ko00512)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 GN=B3GNT6 OS=Homo sapiens (Human) PE=1 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 [Ceratotherium simum simum]"
ENSG00000198492(YTHDF2)	--	34.11234887	1666	29.988246	1490	29.774973	1504	34.38947131	1647	34.28428574	1679	30.1042867	1525	0.984405599	-0.047336202	normal	0.975975605	0.150719173	normal	0.984136674	0.011701549	normal	0.895327936	0.036504258	normal	--	--	Molecular Function: RNA binding (GO:0003723);; 	--	--	[R]	General function prediction only	YT521-B-like domain	YTH domain-containing family protein 2 GN=YTHDF2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: YTH domain-containing family protein 2 [Galeopterus variegatus]
ENSG00000198498(TMA16)	--	12.49018083	333	10.55371484	315	15.12717763	403	13.8233111	417	13.41047493	371	9.683785083	263	0.899936801	0.292484965	normal	0.940683279	0.213694625	normal	0.125554362	-0.621101024	normal	0.972572149	-0.022069867	normal	--	--	--	"K14860|7.66109e-113|hsa:55319|TMA16, C4orf43; translation machinery associated 16 homolog (S. cerevisiae); K14860 translation machinery-associated protein 16 (A)"	--	--	--	Protein of unknown function (DUF2962)	Translation machinery-associated protein 16 GN=TMA16 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	hypothetical protein PAL_GLEAN10012379 [Pteropus alecto]
ENSG00000198513(ATL1)	--	3.553472	143	3.564600952	172	3.374848452	151	1.179085643	57	1.105685	54	1.179192515	56	8.35E-05	-1.334289574	down	4.00E-08	-1.665200098	down	1.48E-05	-1.415124664	down	2.33E-06	-1.501857732	down	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K17339|0|ggo:101139891|ATL1; atlastin-1 isoform 1; K17339 atlastin [EC:3.6.5.-] (A)	--	[R]	General function prediction only	"Guanylate-binding protein, N-terminal domain"	Atlastin-1 GN=ATL1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: atlastin-1 isoform X3 [Tupaia chinensis] 
ENSG00000198515(CNGA1)	--	0.191675871	2	0	0	0.180827796	1	0.324809004	2	0.493713751	4	0.220970426	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04948|0|mcf:102132290|CNGA1; cyclic nucleotide gated channel alpha 1; K04948 cyclic nucleotide gated channel alpha 1 (A)	cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Phototransduction (ko04744)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Ion transport protein;; Cyclic nucleotide-binding domain	cGMP-gated cation channel alpha-1 GN=CNGA1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	cGMP-gated cation channel [Sus scrofa] 
ENSG00000198517(MAFK)	--	31.95082927	1824	43.21603087	2673	36.78962708	2296	27.06552397	1639	21.7786509	1334	41.21163943	2141	0.972025167	-0.184957675	normal	1.97E-07	-1.02329095	down	0.984586418	-0.109054886	normal	0.235758965	-0.430085127	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09037|2.67837e-91|hsa:7975|MAFK, NFE2U, P18; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K; K09037 transcription factor MAFF/G/K (A)"	--	[K]	Transcription	bZIP Maf transcription factor	Transcription factor MafK GN=MAFK OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcription factor MafK [Galeopterus variegatus]
ENSG00000198520(C1orf228)	--	1.14020292	36	2.218222169	56	0.559901504	17	0.639670697	21	0.770604341	25	1.442982801	35	0.919659733	-0.765181685	normal	0.25090927	-1.137742863	normal	0.839638813	0.972117804	normal	0.669243671	-0.449533767	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf228 GN=C1orf228 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C1orf228 homolog [Ceratotherium simum simum]
ENSG00000198521(ZNF43)	--	5.417487858	173	4.635553408	144	3.838754476	164	4.239028032	132	2.630890444	80	3.116244246	104	0.841856085	-0.41681388	normal	0.076987392	-0.857167973	normal	0.368713245	-0.657721445	normal	0.056788309	-0.628189668	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7594|ZNF43, HTF6, KOX27, ZNF39L1; zinc finger protein 43; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; KRAB box;; XPA protein N-terminal;; C1-like domain"	Zinc finger protein 43 GN=ZNF43 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000198522(GPN1)	--	25.27505225	852	22.02785861	747	28.0760882	952	24.46159979	851	25.975399	864	20.44379528	686	0.977260169	-0.032467978	normal	0.957573187	0.188142107	normal	0.423453093	-0.480141779	normal	0.671377813	-0.108835819	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; 	K06883|0|pps:100969699|GPN1; GPN-loop GTPase 1; K06883 (A)	--	[L]	"Replication, recombination and repair"	"Conserved hypothetical ATP binding protein;; Elongation factor Tu GTP binding domain;; AAA-like domain;; 50S ribosome-binding GTPase;; Ferrous iron transport protein B;; CobW/HypB/UreG, nucleotide-binding domain;; Miro-like protein;; Gtr1/RagA G protein conserved region;; ADP-ribosylation factor family"	GPN-loop GTPase 1 {ECO:0000303|PubMed:20855544} OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: GPN-loop GTPase 1 isoform X1 [Ailuropoda melanoleuca]
ENSG00000198523(PLN)	--	0.122321	3	0	0	0	0	0	0	0	0	0.0800451	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K05852|1.90715e-11|hsa:5350|PLN, CMD1P, CMH18, PLB; phospholamban; K05852 phospholamban (A)"	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Adrenergic signaling in cardiomyocytes (ko04261);; Thyroid hormone signaling pathway (ko04919);; Dilated cardiomyopathy (ko05414)	--	--	Phospholamban	Cardiac phospholamban GN=PLN OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	cardiac phospholamban [Bos taurus] 
ENSG00000198535(C2CD4A)	--	0	0	0.0396991	2	0.0389822	1	0.0596993	3	0.0387966	1	0.0198689	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C2 calcium-dependent domain-containing protein 4A GN=C2CD4A OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: C2 calcium-dependent domain-containing protein 4A [Oryctolagus cuniculus]
ENSG00000198538(ZNF28)	--	1.054333855	84	1.285169722	72	0.852902555	67	1.630396599	132	1.29349344	106	1.973417753	162	0.61376663	0.612244205	normal	0.821635124	0.52738875	normal	0.000145602	1.246802793	up	0.01912358	0.822075144	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; BolA-like protein;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C1-like domain"	Zinc finger protein 28 GN=ZNF28 OS=Homo sapiens (Human) PE=2 SV=5	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 347-like [Galeopterus variegatus]
ENSG00000198542(ITGBL1)	--	0.0859242	2	0	0	0.025171	0	0.2619676	10	0.229091654	9	0.216709	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TW]	Signal transduction mechanisms;; Extracellular structures	EGF-like domain	Integrin beta-like protein 1 (Precursor) GN=ITGBL1 OS=Homo sapiens (Human) PE=2 SV=1	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: integrin beta-like protein 1 isoform X1 [Myotis lucifugus]
ENSG00000198551(ZNF627)	--	3.845224572	179	3.011018737	151	3.308773775	135	3.007538089	144	2.788867828	140	3.322582511	168	0.899808003	-0.341447885	normal	0.961147562	-0.129203994	normal	0.922936479	0.304150508	normal	0.910190277	-0.061967138	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ggo:101151312|ZNF627; zinc finger protein 627; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger"	Zinc finger protein 627 GN=ZNF627 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 564-like isoform X3 [Galeopterus variegatus]
ENSG00000198553(KCNRG)	--	8.326088283	400	7.128863678	378	6.39668651	375	7.799404007	376	7.912329057	373	8.431131122	388	0.962496806	-0.119625549	normal	0.967651295	-0.040474152	normal	0.968685543	0.040713197	normal	0.913514069	-0.041313078	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	Potassium channel regulatory protein GN=KCNRG OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium channel regulatory protein [Orcinus orca] 
ENSG00000198554(WDHD1)	--	12.39220001	1177	11.85618	1171	14.4141094	1362	13.018868	1199	9.440187	897	10.16417402	911	0.98150957	-0.00410961	normal	0.716262283	-0.405387611	normal	0.079011474	-0.587691783	normal	0.096896626	-0.324962498	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K11274|0|ggo:101130838|WDHD1; WD repeat and HMG-box DNA-binding protein 1; K11274 chromosome transmission fidelity protein 4 (A)	--	[R]	General function prediction only	"WD domain, G-beta repeat;; Protein of unknown function (DUF3639);; Eukaryotic translation initiation factor eIF2A;; HMG (high mobility group) box"	WD repeat and HMG-box DNA-binding protein 1 GN=WDHD1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: WD repeat and HMG-box DNA-binding protein 1 isoform X3 [Galeopterus variegatus]
ENSG00000198556(ZNF789)	--	6.070376085	238	5.883820207	265	6.955720087	277	5.407936666	239	2.865666	270	3.4097101	228	0.966819279	-0.024624588	normal	0.966315592	0.005509343	normal	0.91201253	-0.287411198	normal	0.790313523	-0.102903212	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 789 GN=ZNF789 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 789 isoform X1 [Galeopterus variegatus]
ENSG00000198561(CTNND1)	--	55.08126531	5838	60.5366717	6514	59.34280592	6103	57.35037493	6043	55.88172009	5795	55.98202201	5904	0.994242144	0.018953565	normal	0.988032717	-0.190114789	normal	0.993917494	-0.056103176	normal	0.754018971	-0.078158798	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05690|0|hsa:1500|CTNND1, CAS, CTNND, P120CAS, P120CTN, p120, p120(CAS), p120(CTN); catenin (cadherin-associated protein), delta 1; K05690 catenin (cadherin-associated protein), delta 1 (A)"	Rap1 signaling pathway (ko04015);; Adherens junction (ko04520);; Leukocyte transendothelial migration (ko04670)	[TW]	Signal transduction mechanisms;; Extracellular structures	Armadillo/beta-catenin-like repeat;; HEAT repeats	Catenin delta-1 GN=CTNND1 OS=Homo sapiens (Human) PE=1 SV=1	TW	Signal transduction mechanisms;; Extracellular structures	PREDICTED: catenin delta-1 isoform X1 [Tupaia chinensis]
ENSG00000198563(DDX39B)	--	129.3601659	3069	146.6884514	3212	130.8470319	3054	153.8660503	3373	155.7535595	3532	134.068186	3127	0.988400634	0.105381076	normal	0.98800719	0.115535006	normal	0.990311577	0.025775101	normal	0.72414429	0.082460545	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K12812|0|ssc:448813|DDX39B, BAT1; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B (EC:3.6.4.13); K12812 ATP-dependent RNA helicase UAP56/SUB2 [EC:3.6.4.13] (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040);; Influenza A (ko05164)	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Spliceosome RNA helicase DDX39B GN=DDX39B OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: spliceosome RNA helicase DDX39B isoform X1 [Lipotes vexillifer]
ENSG00000198569(SLC34A3)	--	0.283392	9	0.7328877	24	0.38851503	12	0.0624443	2	0.15259631	4	0.62095528	20	--	--	--	0.102787051	-2.228323923	normal	0.978366398	0.663352995	normal	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: sodium-dependent phosphate transmembrane transporter activity (GO:0015321);; Cellular Component: membrane (GO:0016020);; Biological Process: sodium-dependent phosphate transport (GO:0044341);; 	"K14683|0|hsa:142680|SLC34A3, HHRH, NPTIIc; solute carrier family 34 (type II sodium/phosphate cotransporter), member 3; K14683 solute carrier family 34 (sodium-dependent phosphate cotransporter) (A)"	--	--	--	Na+/Pi-cotransporter	Sodium-dependent phosphate transport protein 2C GN=SLC34A3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium-dependent phosphate transport protein 2C [Camelus bactrianus]
ENSG00000198573(SPANXC)	--	0	0	0.397609	1	1.14051	2	0.36197	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Sperm protein associated with nucleus, mapped to X chromosome"	Sperm protein associated with the nucleus on the X chromosome E GN=SPANXE OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000198574(SH2D1B)	--	0	0	0	0	0	0	0	0	0.0258316	0	0.0791848	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K07989|5.88376e-93|pps:100984836|SH2D1B; SH2 domain containing 1B; K07989 EWS/FLI1 activated transcript 2 (A)	Natural killer cell mediated cytotoxicity (ko04650)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SH2 domain	SH2 domain-containing protein 1B GN=SH2D1B OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: SH2 domain-containing protein 1B [Camelus bactrianus]
ENSG00000198576(ARC)	--	0.167854	10	0.148513	9	0	0	0.151453	9	0.0809383	4	0.0659887	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K15867|0|ggo:101141663|ARC; activity-regulated cytoskeleton-associated protein; K15867 activity-regulated cytoskeleton-associated protein (A)	Amphetamine addiction (ko05031)	--	--	Retrotransposon gag protein	Activity-regulated cytoskeleton-associated protein OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: activity-regulated cytoskeleton-associated protein [Galeopterus variegatus]
ENSG00000198585(NUDT16)	--	5.472758484	641	5.490584734	631	5.16996525	652	5.845246994	652	5.762540415	678	6.08127094	634	0.974471469	-0.006269755	normal	0.971066677	0.082029031	normal	0.973517567	-0.048566326	normal	0.985612711	0.008492078	normal	--	--	Molecular Function: hydrolase activity (GO:0016787);; 	K16855|6.03695e-126|nle:100607601|NUDT16; nudix (nucleoside diphosphate linked moiety X)-type motif 16; K16855 U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64] (A)	Purine metabolism (ko00230);; RNA degradation (ko03018)	--	--	NUDIX domain	U8 snoRNA-decapping enzyme GN=NUDT16 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: U8 snoRNA-decapping enzyme isoform X1 [Bubalus bubalis]
ENSG00000198586(TLK1)	--	19.62843844	1253	24.06525415	1469	18.02362637	1343	12.79365077	758	12.8390142	872	16.14591917	965	0.001558322	-0.754745459	normal	0.001102854	-0.772815928	normal	0.397198043	-0.484503253	normal	4.25E-06	-0.668025553	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08864|0|ptr:459729|TLK1; tousled-like kinase 1; K08864 tousled-like kinase [EC:2.7.11.1] (A)	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine-protein kinase tousled-like 1 GN=TLK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase tousled-like 1 [Ceratotherium simum simum]
ENSG00000198589(LRBA)	--	11.73312608	1887	10.56248154	1692	11.599236	1768	10.801604	1758	11.30365546	1807	11.73312229	1810	0.980290709	-0.132879487	normal	0.983665837	0.073376913	normal	0.985660129	0.025558374	normal	0.967880881	-0.013553048	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Beige/BEACH domain;; Domain of Unknown Function (DUF1088);; PH domain associated with Beige/BEACH;; Concanavalin A-like lectin/glucanases superfamily;; WD domain, G-beta repeat"	Lipopolysaccharide-responsive and beige-like anchor protein GN=LRBA OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: lipopolysaccharide-responsive and beige-like anchor protein isoform 1 [Ceratotherium simum simum]
ENSG00000198590(C3orf35)	--	0.246815761	8	0.305426135	9	0.114725239	2	0.169774581	5	0.471343442	12	0.395837611	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	AP20 region protein 1 GN=APRG1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: AP20 region protein 1, partial [Galeopterus variegatus]"
ENSG00000198598(MMP17)	--	14.7704382	542	9.9746505	376	11.3501	487	12.99180115	528	11.61108837	514	8.935758311	382	0.970317037	-0.068390748	normal	0.673200194	0.428130996	normal	0.823646637	-0.357384309	normal	1	-0.00250239	normal	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	"K07997|0|hsa:4326|MMP17, MT4-MMP; matrix metallopeptidase 17 (membrane-inserted) (EC:3.4.24.-); K07997 matrix metalloproteinase-17 (membrane-inserted) [EC:3.4.24.-] (A)"	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	Matrix metalloproteinase-17 (Precursor) GN=MMP17 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: matrix metalloproteinase-17 [Galeopterus variegatus]
ENSG00000198604(BAZ1A)	--	11.0966096	1431	11.951687	1453	12.2814137	1513	17.349057	2172	17.33318718	2214	12.924371	1643	0.107455858	0.570667599	normal	0.092879529	0.585696737	normal	0.980546912	0.110523015	normal	0.021274646	0.433569595	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11655|0|hsa:11177|BAZ1A, ACF1, WALp1, WCRF180, hACF1; bromodomain adjacent to zinc finger domain, 1A; K11655 bromodomain adjacent to zinc finger domain protein 1A (A)"	--	[B]	Chromatin structure and dynamics	"ATP-utilising chromatin assembly and remodelling N-terminal;; Bromodomain;; DDT domain;; PHD-finger;; WSTF, HB1, Itc1p, MBD9 motif 1"	Bromodomain adjacent to zinc finger domain protein 1A GN=BAZ1A OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: bromodomain adjacent to zinc finger domain protein 1A isoform 1 [Odobenus rosmarus divergens] 
ENSG00000198610(AKR1C4)	--	0	0	0	0	0	0	0.417482	10	0.479689	11	0.35329671	8	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K00037|0|hsa:1109|AKR1C4, 3-alpha-HSD, C11, CDR, CHDR, DD-4, DD4, HAKRA; aldo-keto reductase family 1, member C4 (EC:1.1.1.225 1.1.1.357); K00037 3-alpha-hydroxysteroid dehydrogenase [EC:1.1.1.50] K00089 3alpha-hydroxysteroid dehydrogenase (A-specific) [EC:1.1.1.213] K00092 chlordecone reductase [EC:1.1.1.225] K00212 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase [EC:1.3.1.20] (A)"	Primary bile acid biosynthesis (ko00120);; Steroid hormone biosynthesis (ko00140);; Metabolism of xenobiotics by cytochrome P450 (ko00980)	[R]	General function prediction only	Aldo/keto reductase family	Aldo-keto reductase family 1 member C4 GN=AKR1C4 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: aldo-keto reductase family 1 member C23-like protein-like [Equus caballus]
ENSG00000198612(COPS8)	--	40.79162949	1047	37.79523221	1004	40.2452817	1014	31.57059254	797	29.13081137	728	27.84631522	719	0.640538165	-0.423726847	normal	0.423524497	-0.484314764	normal	0.32646429	-0.503389323	normal	0.003325279	-0.471348903	normal	--	--	--	K12181|2.95485e-152|pps:100979569|COPS8; COP9 signalosome subunit 8; K12181 COP9 signalosome complex subunit 8 (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"COP9 signalosome, subunit CSN8"	COP9 signalosome complex subunit 8 GN=COPS8 OS=Homo sapiens (Human) PE=1 SV=1	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: COP9 signalosome complex subunit 8 [Ailuropoda melanoleuca] 
ENSG00000198624(CCDC69)	--	2.492926	173	1.628672123	115	1.989079303	140	2.47507757	173	3.147010942	217	2.281006378	159	0.966996556	-0.030560851	normal	0.011569221	0.886018925	normal	0.957164174	0.173548335	normal	0.340499156	0.33795088	normal	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 69 GN=CCDC69 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 69 [Myotis lucifugus]
ENSG00000198625(MDM4)	--	6.495146522	930	6.909270487	1043	6.406533056	901	5.153627541	738	4.65783578	724	7.617379465	913	0.80445587	-0.363765763	normal	0.192873177	-0.547146225	normal	0.978445027	0.01077834	normal	0.100206753	-0.29589009	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10127|0|nle:100594153|MDM4; Mdm4 p53 binding protein homolog (mouse); K10127 protein Mdm4 (A)	p53 signaling pathway (ko04115);; MicroRNAs in cancer (ko05206)	--	--	"SWIB/MDM2 domain;; Zinc finger, C3HC4 type (RING finger);; Zn-finger in Ran binding protein and others;; Zinc finger, C3HC4 type (RING finger)"	Protein Mdm4 GN=MDM4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: protein Mdm4 isoformX1 [Equus caballus]
ENSG00000198626(RYR2)	--	0.009483745	3	0.012551343	4	0.015631061	4	0.050474958	16	0.030475222	10	0.034253686	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: ryanodine-sensitive calcium-release channel activity (GO:0005219);; Molecular Function: calcium channel activity (GO:0005262);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: cellular calcium ion homeostasis (GO:0006874);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04962|0|hsa:6262|RYR2, ARVC2, ARVD2, RYR-2, RyR, VTSIP; ryanodine receptor 2 (cardiac); K04962 ryanodine receptor 2 (A)"	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Cardiac muscle contraction (ko04260);; Adrenergic signaling in cardiomyocytes (ko04261);; Circadian entrainment (ko04713);; Insulin secretion (ko04911);; Oxytocin signaling pathway (ko04921);; Pancreatic secretion (ko04972);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[T]	Signal transduction mechanisms	"RIH domain;; RyR domain;; Ryanodine Receptor TM 4-6;; SPRY domain;; Inositol 1,4,5-trisphosphate/ryanodine receptor;; MIR domain;; RyR and IP3R Homology associated;; Ion transport protein;; EF-hand domain pair"	Ryanodine receptor 2 GN=RYR2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	ryanodine receptor 2 [Oryctolagus cuniculus] 
ENSG00000198642(KLHL9)	--	13.5711	1182	14.9451	1296	12.1864	1037	11.0017	962	10.8846	946	12.2592	1067	0.872459977	-0.32748065	normal	0.459918484	-0.474928615	normal	0.979807039	0.032805675	normal	0.141839105	-0.261859391	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10447|0|ptr:465018|KLHL9; kelch-like family member 9; K10447 kelch-like protein 9/13 (A)	Ubiquitin mediated proteolysis (ko04120)	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; Kelch motif;; BTB And C-terminal Kelch;; BTB/POZ domain;; Galactose oxidase, central domain;; Kelch motif;; Galactose oxidase, central domain;; Kelch motif"	Kelch-like protein 9 GN=KLHL9 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: kelch-like protein 9 [Ailuropoda melanoleuca] 
ENSG00000198643(FAM3D)	--	0	0	0	0	0.16365979	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM3D (Precursor) GN=FAM3D OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM3D isoform X1 [Ursus maritimus]
ENSG00000198646(NCOA6)	--	9.363768245	1456	9.884775602	1548	9.770081943	1498	8.894985	1384	8.784605	1429	8.974019073	1466	0.979735834	-0.103886214	normal	0.976843946	-0.136687082	normal	0.983473671	-0.03940375	normal	0.679827713	-0.094317537	normal	--	--	--	K14971|0|pps:100977678|NCOA6; nuclear receptor coactivator 6; K14971 nuclear receptor coactivator 6 (A)	--	--	--	Putative nucleic acid-binding region	Nuclear receptor coactivator 6 GN=NCOA6 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: nuclear receptor coactivator 6 isoformX1 [Equus caballus]
ENSG00000198648(STK39)	--	14.04110558	884	14.94948891	960	14.21059097	886	10.08838942	630	10.72347062	615	8.91692463	565	0.276459889	-0.51845368	normal	0.023174484	-0.662559073	normal	0.024606716	-0.655933156	normal	0.000115217	-0.614498932	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08835|0|hsa:27347|STK39, DCHT, PASK, SPAK; serine threonine kinase 39 (EC:2.7.11.1); K08835 serine/threonine-protein kinase OSR1/STK39 [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Oxidative-stress-responsive kinase 1 C terminal	STE20/SPS1-related proline-alanine-rich protein kinase GN=STK39 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: STE20/SPS1-related proline-alanine-rich protein kinase [Odobenus rosmarus divergens]
ENSG00000198650(TAT)	--	0	0	0.031833	2	0.0473472	2	0	0	0.046029	2	0.109787	7	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: L-tyrosine:2-oxoglutarate aminotransferase activity (GO:0004838);; Biological Process: biosynthetic process (GO:0009058);; Biological Process: aromatic amino acid family catabolic process (GO:0009074);; Molecular Function: pyridoxal phosphate binding (GO:0030170);; 	K00815|0|hsa:6898|TAT; tyrosine aminotransferase (EC:2.6.1.5); K00815 tyrosine aminotransferase [EC:2.6.1.5] (A)	"Ubiquinone and other terpenoid-quinone biosynthesis (ko00130);; Cysteine and methionine metabolism (ko00270);; Tyrosine metabolism (ko00350);; Phenylalanine metabolism (ko00360);; Phenylalanine, tyrosine and tryptophan biosynthesis (ko00400);; Biosynthesis of amino acids (ko01230)"	[E]	Amino acid transport and metabolism	Aminotransferase class I and II;; Aminotransferase ubiquitination site;; Beta-eliminating lyase;; Aminotransferase class-V;; DegT/DnrJ/EryC1/StrS aminotransferase family	Tyrosine aminotransferase GN=TAT OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: tyrosine aminotransferase [Orycteropus afer afer]
ENSG00000198663(C6orf89)	--	15.81414633	1330	14.46168284	1100	15.20117031	1125	15.25031993	1375	16.55041658	1518	16.87872819	1426	0.982848354	0.017153621	normal	0.598641219	0.442721564	normal	0.871573856	0.333358629	normal	0.135617764	0.259716863	normal	--	--	--	--	--	--	--	--	Bombesin receptor-activated protein C6orf89 GN=C6orf89 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: bombesin receptor-activated protein C6orf89 homolog [Galeopterus variegatus] 
ENSG00000198668(CALM1)	--	123.0249351	5718	112.5238847	5406	127.8208965	5455	152.4599902	6690	130.6294689	5917	102.4204098	4680	0.987725151	0.195614698	normal	0.992166235	0.108848714	normal	0.980693288	-0.229293408	normal	0.903720659	0.038077004	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	"K02183|1.95549e-103|lve:103080762|CALM1; calmodulin 1 (phosphorylase kinase, delta); K02183 calmodulin (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Phosphatidylinositol signaling system (ko04070);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Dopaminergic synapse (ko04728);; Olfactory transduction (ko04740);; Phototransduction (ko04744);; Inflammatory mediator regulation of TRP channels (ko04750);; Insulin signaling pathway (ko04910);; GnRH signaling pathway (ko04912);; Estrogen signaling pathway (ko04915);; Melanogenesis (ko04916);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Gastric acid secretion (ko04971);; Alzheimer's disease (ko05010);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Pertussis (ko05133);; Tuberculosis (ko05152);; Glioma (ko05214)	[T]	Signal transduction mechanisms	EF hand;; EF-hand domain pair;; EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain;; Cytoskeletal-regulatory complex EF hand;; Secreted protein acidic and rich in cysteine Ca binding region;; Ca2+ insensitive EF hand;; Uncharacterised protein family (UPF0154)	Calmodulin GN=CALM3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	Calmodulin [Tupaia chinensis]
ENSG00000198670(LPA)	--	0	0	0.0139777	2	0	0	0.0141113	2	0.00681617	0	0.0139056	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K09644|0|hsa:4018|LPA, AK38, APOA, LP; lipoprotein, Lp(a) (EC:3.4.21.-); K09644 apolipoprotein(a) [EC:3.4.21.-] (A)"	--	--	--	Kringle domain;; Trypsin;; Domain of unknown function (DUF1986)	Apolipoprotein(a) (Precursor) GN=LPA OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	"apolipoprotein(a), partial [Erinaceus europaeus] "
ENSG00000198673(FAM19A2)	--	0.042317741	2	0.123563525	4	0.479109208	4	0	0	0.030050475	0	0.031800902	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TAFA family	Protein FAM19A2 (Precursor) GN=FAM19A2 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM19A2 [Ochotona princeps]
ENSG00000198677(TTC37)	--	22.94160035	2440	23.24717558	2465	22.73743643	2374	26.28451834	2793	24.76123795	2624	26.970576	2868	0.981476822	0.164005587	normal	0.987559031	0.068712654	normal	0.95702514	0.264280265	normal	0.390690789	0.165562568	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K12600|0|hsa:9652|TTC37, KIAA0372, Ski3, THES; tetratricopeptide repeat domain 37; K12600 superkiller protein 3 (A)"	RNA degradation (ko03018)	[A]	RNA processing and modification	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Fis1 C-terminal tetratricopeptide repeat;; Tetratricopeptide repeat"	Tetratricopeptide repeat protein 37 GN=TTC37 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: tetratricopeptide repeat protein 37 [Ceratotherium simum simum]
ENSG00000198680(TUSC1)	--	8.70695	245	7.87289	226	7.89167	229	10.0687	290	12.6432	359	8.458	241	0.94316165	0.211220337	normal	0.120522962	0.642793555	normal	0.965376864	0.064975799	normal	0.235934644	0.324885223	normal	--	--	--	--	--	--	--	--	Tumor suppressor candidate gene 1 protein GN=TUSC1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: tumor suppressor candidate gene 1 protein [Odobenus rosmarus divergens]
ENSG00000198681(MAGEA1)	--	0	0	0.0326917	1	0	0	0.0334472	1	0.0993368	2	0.133953	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 1 GN=MAGEA1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: melanoma-associated antigen 10-like isoform X2 [Bos taurus] 
ENSG00000198682(PAPSS2)	--	20.74494	1521	17.651998	1308	18.80899	1377	19.25281	1414	19.19072	1396	24.23547	1772	0.977045619	-0.13592784	normal	0.980778581	0.072428778	normal	0.846895211	0.35521384	normal	0.691636075	0.102979919	normal	[P]	Inorganic ion transport and metabolism	Molecular Function: sulfate adenylyltransferase (ATP) activity (GO:0004781);; 	K13811|0|pps:100981609|PAPSS2; 3'-phosphoadenosine 5'-phosphosulfate synthase 2; K13811 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] (A)	Purine metabolism (ko00230);; Selenocompound metabolism (ko00450);; Sulfur metabolism (ko00920)	[F]	Nucleotide transport and metabolism	Adenylylsulphate kinase;; ATP-sulfurylase;; PUA-like domain;; AAA domain;; AAA domain	Adenylyl-sulfate kinase GN=PAPSS2 OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 isoform X1 [Elephantulus edwardii]
ENSG00000198689(SLC9A6)	--	10.6950505	694	9.2107902	604	8.14274547	531	6.60722867	467	7.4806728	498	6.7182182	449	0.089141506	-0.600712462	normal	0.893536645	-0.299003435	normal	0.927426168	-0.249514112	normal	0.04290436	-0.392847335	normal	[P]	Inorganic ion transport and metabolism	Biological Process: cation transport (GO:0006812);; Molecular Function: solute:proton antiporter activity (GO:0015299);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; 	"K12041|0|hsa:10479|SLC9A6, MRSA, NHE6; solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6; K12041 solute carrier family 9 (sodium/hydrogen exchanger), member 6/7 (A)"	Cardiac muscle contraction (ko04260)	[P]	Inorganic ion transport and metabolism	Sodium/hydrogen exchanger family	Sodium/hydrogen exchanger 6 GN=SLC9A6 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/hydrogen exchanger 6 isoform X2 [Oryctolagus cuniculus]
ENSG00000198690(FAN1)	--	10.42384584	978	11.215865	983	13.35171194	1138	12.97367764	1133	10.14244818	1046	11.4872582	1044	0.964166908	0.181144665	normal	0.977495395	0.068091414	normal	0.973330263	-0.132486407	normal	0.902758197	0.035415893	normal	--	--	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	K15363|0|pps:100968545|FAN1; FANCD2/FANCI-associated nuclease 1; K15363 fanconi-associated nuclease 1 [EC:3.1.21.- 3.1.4.1] (A)	Fanconi anemia pathway (ko03460)	[S]	Function unknown	VRR-NUC domain	Fanconi-associated nuclease 1 GN=FAN1 OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: fanconi-associated nuclease 1 isoform X1 [Equus przewalskii] 
ENSG00000198691(ABCA4)	--	0.039642047	3	0.013191325	1	0.00638003	0	0.013268276	1	0.012866428	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K05644|0|hsa:24|ABCA4, ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1; ATP-binding cassette, sub-family A (ABC1), member 4; K05644 ATP-binding cassette, subfamily A (ABC1), member 4 (A)"	ABC transporters (ko02010)	[IR]	Lipid transport and metabolism;; General function prediction only	ABC-2 family transporter protein;; ABC transporter;; AAA domain	Retinal-specific ATP-binding cassette transporter GN=ABCA4 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: retinal-specific ATP-binding cassette transporter [Ceratotherium simum simum]
ENSG00000198692(EIF1AY)	--	33.811858	579	34.367406	555	40.589482	669	18.737492	311	14.481378	221	14.217201	220	8.63E-05	-0.924077812	normal	6.16E-10	-1.343853162	down	4.55E-15	-1.606130826	down	3.49E-13	-1.283665362	down	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation initiation factor activity (GO:0003743);; Biological Process: translational initiation (GO:0006413);; 	"K03236|2.24167e-65|apla:101796918|eukaryotic translation initiation factor 1A, Y-chromosomal-like; K03236 translation initiation factor 1A (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Translation initiation factor 1A / IF-1	"Eukaryotic translation initiation factor 1A, Y-chromosomal GN=EIF1AY OS=Homo sapiens (Human) PE=1 SV=4"	J	"Translation, ribosomal structure and biogenesis"	"Eukaryotic translation initiation factor 1A, X-chromosomal, partial [Bos mutus]"
ENSG00000198695(MT-ND6)	--	3013.31	11185	2739.94	10662	2629.48	10109	2455.34	9904	2620	9544	2561.22	9780	0.991230002	-0.206284162	normal	0.99243493	-0.181211513	normal	0.995966123	-0.056016842	normal	0.505119527	-0.150100935	normal	--	--	Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K03884|1.08102e-52|hsa:4541|ND6, MTND6, MT-ND6; NADH dehydrogenase, subunit 6 (complex I); K03884 NADH-ubiquinone oxidoreductase chain 6 [EC:1.6.5.3] (A)"	Oxidative phosphorylation (ko00190);; Parkinson's disease (ko05012)	--	--	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	NADH-ubiquinone oxidoreductase chain 6 GN=MT-ND6 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	NADH dehydrogenase subunit 6 [Oryctolagus cuniculus] 
ENSG00000198700(IPO9)	--	38.7182137	4080	37.42480133	4082	37.67729725	4065	28.53145088	3779	32.23979217	3978	30.24917399	3675	0.988048073	-0.141341571	normal	0.99139021	-0.058637457	normal	0.986936803	-0.153742362	normal	0.584122188	-0.118234955	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	--	--	[UY]	"Intracellular trafficking, secretion, and vesicular transport;; Nuclear structure"	Importin-beta N-terminal domain;; Exportin 1-like protein	Importin-9 GN=IPO9 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: importin-9 isoform X1 [Galeopterus variegatus]
ENSG00000198707(CEP290)	--	7.859467284	962	7.494960809	1032	9.596612328	1106	9.655728388	1104	8.071003673	1089	8.233794488	1069	0.966724084	0.167549181	normal	0.978619239	0.056054459	normal	0.97937917	-0.057301274	normal	0.847664645	0.052381352	normal	--	--	--	"K16533|0|hsa:80184|CEP290, 3H11Ag, BBS14, CT87, JBTS5, LCA10, MKS4, NPHP6, POC3, SLSN6, rd16; centrosomal protein 290kDa; K16533 centrosomal protein CEP290 (A)"	--	--	--	--	Centrosomal protein of 290 kDa GN=CEP290 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	centrosomal protein of 290 kDa [Felis catus] 
ENSG00000198712(MT-CO2)	--	18343.4	113237	15963.6	95180	16344.1	99638	13112.7	84825	14950.5	93275	14116	90288	0.961970987	-0.447609222	normal	0.999375201	-0.050593745	normal	0.999090768	-0.150450851	normal	0.42009184	-0.219876718	normal	[C]	Energy production and conversion	--	"K02261|6.06424e-106|hsa:4513|COX2, COII, MTCO2, MT-CO2; cytochrome c oxidase subunit II; K02261 cytochrome c oxidase subunit 2 (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"Cytochrome C oxidase subunit II, transmembrane domain"	Cytochrome c oxidase subunit 2 GN=MT-CO2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	cytochrome oxidase subunit II [Suncus murinus]
ENSG00000198715(GLMP)	--	41.9158511	848	42.2915081	963	39.83709358	889	38.82549503	876	35.36286741	786	55.8872736	1237	0.97771541	0.01600581	normal	0.886052748	-0.313886371	normal	0.469999511	0.467621419	normal	0.866978052	0.082353539	normal	--	--	--	--	--	--	--	"Lysosomal transcription factor, NCU-G1"	Lysosomal protein NCU-G1 (Precursor) GN=C1orf85 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: lysosomal protein NCU-G1 isoform X1 [Galeopterus variegatus]
ENSG00000198718(TOGARAM1)	--	4.91778376	444	6.294882182	623	5.195856551	506	5.223990697	604	5.4826232	556	8.557435894	758	0.696266026	0.411930328	normal	0.953644102	-0.18509791	normal	0.135422641	0.573359718	normal	0.411645173	0.26537253	normal	--	--	--	--	--	[S]	Function unknown	CLASP N terminal;; HEAT repeats	Protein FAM179B GN=FAM179B OS=Homo sapiens (Human) PE=1 SV=4	S	Function unknown	PREDICTED: protein FAM179B isoform X3 [Equus przewalskii]
ENSG00000198719(DLL1)	--	0.032077154	2	0.06298157	4	0	0	0.064097944	4	0.093154927	5	0.015861036	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Biological Process: cell communication (GO:0007154);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	"K06051|0|hsa:28514|DLL1, DELTA1, DL1, Delta; delta-like 1 (Drosophila); K06051 delta (A)"	Notch signaling pathway (ko04330)	[T]	Signal transduction mechanisms	EGF-like domain;; N terminus of Notch ligand;; Delta serrate ligand;; Human growth factor-like EGF;; EGF-like domain;; Calcium-binding EGF domain	Delta-like protein 1 (Precursor) GN=DLL1 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: delta-like protein 1 isoform X3 [Ursus maritimus]
ENSG00000198720(ANKRD13B)	--	9.125174929	595	8.42219103	586	9.84454744	674	12.2993143	775	9.196612246	601	9.090944984	597	0.828686456	0.349681279	normal	0.972824203	0.014999546	normal	0.955824807	-0.182872832	normal	0.81891411	0.067140355	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	GPCR-chaperone;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 13B GN=ANKRD13B OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 13B [Galeopterus variegatus]
ENSG00000198721(ECI2)	--	30.13554078	689	25.52469087	590	29.62011288	679	33.99922136	792	30.7493003	696	27.02731413	624	0.960976256	0.169810801	normal	0.945002892	0.216434552	normal	0.966558965	-0.129855193	normal	0.745979882	0.087446821	normal	[I]	Lipid transport and metabolism	Molecular Function: fatty-acyl-CoA binding (GO:0000062);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: 3-hydroxyisobutyryl-CoA hydrolase activity (GO:0003860);; Biological Process: metabolic process (GO:0008152);; 	"K13239|0|pps:100974366|ECI2; enoyl-CoA delta isomerase 2; K13239 peroxisomal 3,2-trans-enoyl-CoA isomerase [EC:5.3.3.8] (A)"	Fatty acid degradation (ko00071);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	Enoyl-CoA hydratase/isomerase family;; Acyl CoA binding protein	"Enoyl-CoA delta isomerase 2, mitochondrial (Precursor) GN=ECI2 OS=Homo sapiens (Human) PE=1 SV=4"	I	Lipid transport and metabolism	"PREDICTED: enoyl-CoA delta isomerase 2, mitochondrial isoform X1 [Myotis lucifugus]"
ENSG00000198722(UNC13B)	--	5.742926353	829	5.840943344	843	5.5194518	798	6.057974948	869	6.27476837	894	6.689954837	962	0.977090942	0.037084681	normal	0.975809609	0.063205532	normal	0.92943122	0.260905765	normal	0.606625381	0.120775485	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	K15293|0|mcf:102115169|UNC13B; unc-13 homolog B (C. elegans); K15293 protein unc-13 (A)	Synaptic vesicle cycle (ko04721)	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Munc13 (mammalian uncoordinated) homology domain;; Domain of Unknown Function (DUF1041);; C2 domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Protein unc-13 homolog B GN=UNC13B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: uncharacterized protein LOC102738342, partial [Leptonychotes weddellii]"
ENSG00000198723(C19orf45)	--	27.1815821	846	25.47396827	730	21.35037841	693	21.85688811	688	25.45470001	799	29.07159909	901	0.862273316	-0.328418554	normal	0.970641059	0.108657278	normal	0.792685257	0.369670886	normal	0.872762476	0.053189279	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4601)	Uncharacterized protein C19orf45 GN=C19orf45 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C19orf45 homolog [Equus caballus]
ENSG00000198727(MT-CYB)	--	5528.91	75992	5511.81	71359	5303.83	69963	5025.75	68833	5110.84	70986	5295.59	74288	0.998682441	-0.173575733	normal	0.999235008	-0.028986818	normal	0.999193925	0.078243949	normal	0.908019443	-0.042482497	normal	[C]	Energy production and conversion	--	"K00412|5.52085e-178|hsa:4519|CYTB, MTCYB, MT-CYB; cytochrome b; K00412 ubiquinol-cytochrome c reductase cytochrome b subunit (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	--	Cytochrome b GN=MT-CYB OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	cytochrome b (mitochondrion) (mitochondrion) [Prionailurus viverrinus]
ENSG00000198728(LDB1)	--	25.106123	1762	24.9747098	1707	25.558657	1780	25.3481929	1745	25.4018619	1740	21.82147709	1552	0.985059165	-0.044779914	normal	0.985079951	0.006192256	normal	0.966645569	-0.205852669	normal	0.730426959	-0.080933442	normal	--	--	--	K15617|0|pon:100460910|LDB1; LIM domain binding 1; K15617 LIM domain-binding protein 1 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	LIM-domain binding protein	LIM domain-binding protein 1 GN=LDB1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LIM domain-binding protein 1 isoform 1 [Odobenus rosmarus divergens]
ENSG00000198729(PPP1R14C)	--	0.395677	13	0.353489	12	0.176918	5	1.66734	56	1.59116	52	1.11671	37	0.000656535	1.956008665	up	0.001173462	1.965673731	up	0.000768311	2.5569167	up	2.25E-05	2.249368353	up	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: regulation of phosphorylation (GO:0042325);; 	"K17556|7.0673e-39|hgl:101722824|Ppp1r14c; protein phosphatase 1, regulatory (inhibitor) subunit 14C; K17556 protein phosphatase 1 regulatory subunit 14C (A)"	--	--	--	PKC-activated protein phosphatase-1 inhibitor	Protein phosphatase 1 regulatory subunit 14C GN=PPP1R14C OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 14C [Elephantulus edwardii]
ENSG00000198730(CTR9)	--	13.42291826	1303	11.95971047	1197	13.04618356	1294	14.64452522	1432	15.66631572	1477	12.49927942	1238	0.979132386	0.105243745	normal	0.927884152	0.281499451	normal	0.980474159	-0.07203167	normal	0.632191413	0.106865914	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15176|0|cjc:100390183|CTR9; CTR9, Paf1/RNA polymerase II complex component; K15176 RNA polymerase-associated protein CTR9 (A)"	--	[P]	Inorganic ion transport and metabolism	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat"	RNA polymerase-associated protein CTR9 homolog GN=CTR9 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: RNA polymerase-associated protein CTR9 homolog [Dasypus novemcinctus]
ENSG00000198732(SMOC1)	--	3.698611026	233	4.330022	271	3.181316847	196	1.440449677	104	2.887069672	169	7.674503	472	2.61E-05	-1.182577425	down	0.092763729	-0.69771766	normal	2.62E-08	1.253212992	up	0.972519923	0.072520384	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Biological Process: signal transduction (GO:0007165);; 	--	--	[R]	General function prediction only	Thyroglobulin type-1 repeat;; Secreted protein acidic and rich in cysteine Ca binding region;; Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	SPARC-related modular calcium-binding protein 1 (Precursor) GN=SMOC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SPARC-related modular calcium-binding protein 1 isoform X3 [Felis catus]
ENSG00000198734(F5)	--	0.026017149	4	0.019698019	3	0.006517152	0	0.342579179	52	0.51519997	79	0.230840874	36	1.55E-07	3.247375939	up	3.26E-14	4.139646892	up	2.12E-07	4.628585253	up	5.17E-07	4.552007245	up	--	--	Molecular Function: copper ion binding (GO:0005507);; Biological Process: blood coagulation (GO:0007596);; 	"K03902|0|hsa:2153|F5, FVL, PCCF, RPRGL1, THPH2; coagulation factor V (proaccelerin, labile factor); K03902 coagulation factor V (labile factor) (A)"	Complement and coagulation cascades (ko04610)	--	--	F5/8 type C domain;; Multicopper oxidase	Coagulation factor V light chain (Precursor) GN=F5 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	PREDICTED: coagulation factor V [Odobenus rosmarus divergens]
ENSG00000198736(MSRB1)	--	23.18115568	523	19.91745738	453	21.62360735	495	26.09520212	590	25.37568128	566	26.2702147	584	0.96247019	0.142676964	normal	0.893288016	0.298969966	normal	0.937839907	0.229601918	normal	0.335784869	0.221111374	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: peptide-methionine (R)-S-oxide reductase activity (GO:0033743);; Biological Process: oxidation-reduction process (GO:0055114);; 	K07305|6.01569e-42|nle:100604004|MSRB1; methionine sulfoxide reductase B1; K07305 peptide-methionine (R)-S-oxide reductase [EC:1.8.4.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SelR domain	Methionine-R-sulfoxide reductase B1 GN=MSRB1 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	"selenoprotein X, 1 [Equus caballus]"
ENSG00000198740(ZNF652)	--	4.167675457	673	4.36060547	765	3.49620548	592	3.461270112	572	3.57620458	602	3.593879924	596	0.920391966	-0.264767068	normal	0.803532828	-0.36630435	normal	0.973649118	0.001420097	normal	0.312281383	-0.219139839	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 652 GN=ZNF652 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 652 isoform X1 [Tupaia chinensis]
ENSG00000198742(SMURF1)	--	12.428715	1439	12.61676941	1464	11.55083553	1335	15.2487855	1761	17.210974	1988	13.663078	1582	0.945132801	0.260244539	normal	0.701014614	0.419602385	normal	0.953873432	0.236372169	normal	0.056967176	0.309467573	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ubiquitin-protein transferase activity (GO:0004842);; Molecular Function: protein binding (GO:0005515);; 	K04678|0|mcf:102126087|SMURF1; SMAD specific E3 ubiquitin protein ligase 1; K04678 E3 ubiquitin ligase SMURF1/2 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Endocytosis (ko04144);; TGF-beta signaling pathway (ko04350)	[O]	"Posttranslational modification, protein turnover, chaperones"	HECT-domain (ubiquitin-transferase);; WW domain;; C2 domain	E3 ubiquitin-protein ligase SMURF1 GN=SMURF1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase SMURF1 [Odobenus rosmarus divergens]
ENSG00000198743(SLC5A3)	--	42.58505	1308	47.59809	1592	47.54556	1620	37.87277	1397	31.14833	1084	43.6243	1379	0.981570599	0.064064396	normal	0.111864449	-0.575235552	normal	0.952897144	-0.240419261	normal	0.239629508	-0.248904468	normal	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14383|0|ptr:749966|SLC5A3; solute carrier family 5 (sodium/myo-inositol cotransporter), member 3; K14383 solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium:solute symporter family	Sodium/myo-inositol cotransporter GN=SLC5A3 OS=Homo sapiens (Human) PE=3 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: sodium/myo-inositol cotransporter isoform X1 [Physeter catodon] 
ENSG00000198746(GPATCH3)	--	3.82461	156	4.571333079	204	3.73611	167	3.786683036	164	4.44572	180	4.24906	185	0.967064981	0.040924412	normal	0.947766738	-0.200415905	normal	0.96004046	0.138196263	normal	0.985016047	-0.01553022	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	G-patch domain	G patch domain-containing protein 3 GN=GPATCH3 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: G patch domain-containing protein 3 [Trichechus manatus latirostris]
ENSG00000198752(CDC42BPB)	--	40.8641	5757	39.65942	5538	38.98932	5693	43.20158	6226	44.31047	6483	45.292262	6358	0.993461976	0.08213502	normal	0.986176122	0.205817973	normal	0.990855065	0.151054488	normal	0.495969437	0.145478197	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K16307|0|hsa:9578|CDC42BPB, MRCKB; CDC42 binding protein kinase beta (DMPK-like) (EC:2.7.11.1); K16307 serine/threonine-protein kinase MRCK [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	CNH domain;; Protein kinase domain;; Protein tyrosine kinase;; DMPK coiled coil domain like;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Serine/threonine-protein kinase MRCK beta OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase MRCK beta isoform X2 [Galeopterus variegatus]
ENSG00000198754(OXCT2)	--	0.304114	11	0.240902	9	0.393139	14	0.433931	16	0.588143	21	0.13613	5	--	--	--	0.932024919	1.079470753	normal	--	--	--	--	--	--	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: CoA-transferase activity (GO:0008410);; 	"K01027|0|hsa:64064|OXCT2, SCOTT; 3-oxoacid CoA transferase 2 (EC:2.8.3.5); K01027 3-oxoacid CoA-transferase [EC:2.8.3.5] (A)"	"Synthesis and degradation of ketone bodies (ko00072);; Valine, leucine and isoleucine degradation (ko00280);; Butanoate metabolism (ko00650)"	[C]	Energy production and conversion	Coenzyme A transferase	"Succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial (Precursor) GN=OXCT2 OS=Homo sapiens (Human) PE=2 SV=2"	C	Energy production and conversion	"PREDICTED: succinyl-CoA:3-ketoacid coenzyme A transferase 2, mitochondrial-like [Oryctolagus cuniculus]"
ENSG00000198755(RPL10A)	--	791.72	7898	669.987	6743	705.989	7238	799.5	8268	791.149	7897	604.547	6169	0.995437935	0.035212063	normal	0.988069242	0.206444716	normal	0.982882443	-0.238791799	normal	0.98464129	0.007706919	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02865|8.56041e-143|tup:102497757|RPL10A; ribosomal protein L10a; K02865 large subunit ribosomal protein L10Ae (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L1p/L10e family	60S ribosomal protein L10a GN=RPL10A OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L10a-like [Myotis davidii]
ENSG00000198756(COLGALT2)	--	0.1757237	14	0.29692186	27	0.171977504	14	0.079193131	6	0.089991502	7	0.195440132	17	--	--	--	0.280357819	-1.762920887	normal	--	--	--	--	--	--	--	--	--	"K11703|0|hsa:23127|COLGALT2, C1orf17, GLT25D2; collagen beta(1-O)galactosyltransferase 2 (EC:2.4.1.50); K11703 collagen beta-1,O-galactosyltransferase [EC:2.4.1.50] (A)"	Lysine degradation (ko00310);; Other types of O-glycan biosynthesis (ko00514)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glycosyltransferase family 25 (LPS biosynthesis protein);; Glycosyl transferase family 2	Procollagen galactosyltransferase 2 (Precursor) GN=COLGALT2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: procollagen galactosyltransferase 2 [Odobenus rosmarus divergens]
ENSG00000198758(EPS8L3)	--	0	0	0	0	0	0	0.238086827	12	0.420185995	18	0.136331333	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K17277|0|pps:100992031|EPS8L3; EPS8-like 3; K17277 epidermal growth factor receptor kinase substrate 8 (A)	--	[T]	Signal transduction mechanisms	Phosphotyrosine-binding domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Epidermal growth factor receptor kinase substrate 8-like protein 3 GN=EPS8L3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor receptor kinase substrate 8-like protein 3 isoform X3 [Equus przewalskii]
ENSG00000198763(MT-ND2)	--	6703.26	76700	6404.15	70025	6218.56	69436	5683.12	66358	5249.68	60874	5578.01	66443	0.997598055	-0.239783267	normal	0.997712877	-0.223465287	normal	0.999169157	-0.071856468	normal	0.519581419	-0.179769744	normal	--	--	--	"K03879|2.81856e-62|hsa:4536|ND2, MTND2, MT-ND2; MTND2; K03879 NADH-ubiquinone oxidoreductase chain 2 [EC:1.6.5.3] (A)"	Oxidative phosphorylation (ko00190);; Parkinson's disease (ko05012)	[C]	Energy production and conversion	--	NADH-ubiquinone oxidoreductase chain 2 GN=MT-ND2 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	NADH dehydrogenase subunit 2 [Camelus dromedarius] 
ENSG00000198771(RCSD1)	--	0.015322586	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18615|0|hsa:92241|RCSD1, CAPZIP, MK2S4; RCSD domain containing 1; K18615 CapZ-interacting protein (A)"	--	--	--	"RCSD region;; WASH complex subunit CAP-Z interacting, central region"	CapZ-interacting protein GN=RCSD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: capZ-interacting protein [Galeopterus variegatus]
ENSG00000198774(RASSF9)	--	0.728308	60	1.0854	89	0.818474	66	1.02085	85	2.2968	191	1.97069	164	0.909686335	0.461692892	normal	0.0011114	1.067601549	up	6.86E-05	1.285555609	up	0.094068364	1.013555405	normal	--	--	--	K09856|0|pps:100993308|RASSF9; Ras association (RalGDS/AF-6) domain family (N-terminal) member 9; K09856 Ras association domain-containing protein 9/10 (A)	--	[W]	Extracellular structures	Ras association (RalGDS/AF-6) domain	Ras association domain-containing protein 9 GN=RASSF9 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: ras association domain-containing protein 9 [Galeopterus variegatus]
ENSG00000198780(FAM169A)	--	5.7865	561	7.842292032	693	5.796790003	546	4.803197815	461	4.863135226	459	4.200601634	409	0.878155751	-0.313118453	normal	0.079711346	-0.614128614	normal	0.670673237	-0.423730655	normal	0.015400431	-0.459459852	normal	--	--	--	--	--	--	--	--	Soluble lamin-associated protein of 75 kDa GN=FAM169A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: soluble lamin-associated protein of 75 kDa [Galeopterus variegatus]
ENSG00000198783(ZNF830)	--	3.06058	125	4.37369	181	3.87367	159	4.582	189	4.81536	195	3.7456	153	0.564235097	0.559993112	normal	0.96315254	0.085370582	normal	0.966364697	-0.063173977	normal	0.653278166	0.185952356	normal	--	--	--	"K13104|0|ptr:454580|ZNF830, CCDC16; zinc finger protein 830; K13104 zinc finger protein 830 (A)"	--	[S]	Function unknown	--	Zinc finger protein 830 GN=ZNF830 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: zinc finger protein 830 [Leptonychotes weddellii]
ENSG00000198785(GRIN3A)	--	0.0798428	12	0.0462469	7	0.0131113	1	0.0466271	7	0.116394	17	0.059375	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05213|0|hsa:116443|GRIN3A, GluN3A, NMDAR-L, NR3A; glutamate receptor, ionotropic, N-methyl-D-aspartate 3A; K05213 glutamate receptor ionotropic, NMDA 3A (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Glutamatergic synapse (ko04724);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033);; Alcoholism (ko05034)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"Ligand-gated ion channel;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site;; Receptor family ligand binding region"	"Glutamate receptor ionotropic, NMDA 3A (Precursor) GN=GRIN3A OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, NMDA 3A isoformX1 [Canis lupus familiaris]"
ENSG00000198786(MT-ND5)	--	2804.78	72532	2811.99	68046	2592.74	64110	2410	62175	2337.35	61430	2330.73	62053	0.997086551	-0.253109493	normal	0.998521749	-0.168989577	normal	0.999153902	-0.055338564	normal	0.569803081	-0.162123401	normal	[CP]	Energy production and conversion;; Inorganic ion transport and metabolism	--	"K03883|0|hsa:4540|ND5, MTND5, MT-ND5; NADH dehydrogenase, subunit 5 (complex I); K03883 NADH-ubiquinone oxidoreductase chain 5 [EC:1.6.5.3] (A)"	Oxidative phosphorylation (ko00190);; Parkinson's disease (ko05012)	[C]	Energy production and conversion	"NADH-Ubiquinone/plastoquinone (complex I), various chains"	NADH-ubiquinone oxidoreductase chain 5 GN=MT-ND5 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	NADH dehydrogenase subunit 5 (mitochondrion) [Rupicapra rupicapra cartusiana]
ENSG00000198791(CNOT7)	--	39.83798064	1896	39.01546403	1962	42.26317578	1892	39.11632026	2109	42.46764481	2151	35.79057237	1893	0.982382372	0.122673586	normal	0.983279277	0.111174067	normal	0.986361536	-0.007523108	normal	0.746526681	0.076216273	normal	[A]	RNA processing and modification	--	"K12581|0|umr:103681341|CNOT7; CCR4-NOT transcription complex, subunit 7; K12581 CCR4-NOT transcription complex subunit 7/8 (A)"	RNA degradation (ko03018)	[A]	RNA processing and modification	CAF1 family ribonuclease	CCR4-NOT transcription complex subunit 7 GN=CNOT7 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: CCR4-NOT transcription complex subunit 7 isoform X1 [Myotis davidii] 
ENSG00000198792(TMEM184B)	--	32.91799567	2109	29.42353413	1903	34.06075564	2246	32.21401029	2044	29.51914935	1841	30.46325794	2000	0.985688007	-0.075939961	normal	0.98457339	-0.069156613	normal	0.976994411	-0.175524051	normal	0.612216551	-0.109731629	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Organic solute transporter Ostalpha	Transmembrane protein 184B GN=TMEM184B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: transmembrane protein 184B [Ceratotherium simum simum]
ENSG00000198793(MTOR)	--	10.308009	1876	9.642146	1643	10.37855212	1897	11.851395	1980	10.955847	1920	11.166382	2024	0.985938276	0.046970893	normal	0.968471809	0.203174139	normal	0.984678736	0.085132456	normal	0.621022958	0.108370149	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: protein binding (GO:0005515);; Molecular Function: kinase activity (GO:0016301);; 	"K07203|0|hsa:2475|MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1; mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1); K07203 FKBP12-rapamycin complex-associated protein (A)"	ErbB signaling pathway (ko04012);; HIF-1 signaling pathway (ko04066);; mTOR signaling pathway (ko04150);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910);; Thyroid hormone signaling pathway (ko04919);; Adipocytokine signaling pathway (ko04920);; Type II diabetes mellitus (ko04930);; Pathways in cancer (ko05200);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Glioma (ko05214);; Prostate cancer (ko05215);; Acute myeloid leukemia (ko05221);; Central carbon metabolism in cancer (ko05230);; Choline metabolism in cancer (ko05231)	[L]	"Replication, recombination and repair"	FAT domain;; Phosphatidylinositol 3- and 4-kinase;; Domain of unknown function (DUF3385);; Rapamycin binding domain;; FATC domain;; HEAT repeats;; Adaptin N terminal region;; HEAT repeat;; HEAT-like repeat	Serine/threonine-protein kinase mTOR GN=MTOR OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: serine/threonine-protein kinase mTOR [Tupaia chinensis]
ENSG00000198794(SCAMP5)	--	13.79750216	610	14.52978065	628	13.98564548	670	13.66130859	585	11.9866317	563	12.41307591	606	0.969827583	-0.090970872	normal	0.955440486	-0.178601676	normal	0.962541033	-0.152771995	normal	0.567589354	-0.142377339	normal	--	--	Biological Process: protein transport (GO:0015031);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	SCAMP family	Secretory carrier-associated membrane protein 5 GN=SCAMP5 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: secretory carrier-associated membrane protein 5 [Bubalus bubalis]
ENSG00000198795(ZNF521)	--	0.010884851	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Drought induced 19 protein (Di19), zinc-binding;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2 type zinc-finger (2 copies)"	Zinc finger protein 521 GN=ZNF521 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 521-like isoform X1 [Tupaia chinensis]
ENSG00000198796(ALPK2)	--	2.15691007	449	2.53721846	562	3.022477301	582	9.830088232	2175	10.70080507	2252	11.23147326	2424	0	2.241549562	up	0	1.97826572	up	0	2.047176432	up	1.11E-53	2.083919697	up	--	--	Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08868|0|hsa:115701|ALPK2, HAK; alpha-kinase 2; K08868 alpha-kinase (A)"	--	--	--	Alpha-kinase family;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Alpha-protein kinase 2 GN=ALPK2 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: alpha-protein kinase 2 isoform X2 [Equus przewalskii]
ENSG00000198797(BRINP2)	--	0.0141717	1	0	0	0	0	0	0	0	0	0.0281252	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MAC/Perforin domain	BMP/retinoic acid-inducible neural-specific protein 2 (Precursor) GN=BRINP2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM5B [Pantholops hodgsonii]
ENSG00000198799(LRIG2)	--	1.847699346	351	1.670637	317	1.431545634	264	1.428454	269	2.037836	384	1.799549	340	0.746062497	-0.412626936	normal	0.924127615	0.254094146	normal	0.845479273	0.354909386	normal	0.869462044	0.070673721	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Leucine Rich repeats (2 copies);; Leucine rich repeats (6 copies);; Leucine Rich Repeat;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Leucine Rich repeat;; CD80-like C2-set immunoglobulin domain;; Leucine rich repeat	Leucine-rich repeats and immunoglobulin-like domains protein 2 (Precursor) GN=LRIG2 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X2 [Camelus dromedarius]
ENSG00000198804(MT-CO1)	--	17973.3	359351	14910.6	289856	15693.5	308235	14165.8	283980	15247	308206	15624.2	319572	0.996344476	-0.37043485	normal	0.999756422	0.067131701	normal	0.999791977	0.043818667	normal	0.829100354	-0.091396476	normal	[C]	Energy production and conversion	--	"K02256|0|hsa:4512|COX1, COI, MTCO1, MT-CO1; cytochrome c oxidase subunit I; K02256 cytochrome c oxidase subunit 1 [EC:1.9.3.1] (A)"	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	--	Cytochrome c oxidase subunit 1 GN=MT-CO1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	cytochrome c oxidase subunit I (mitochondrion) [Prionodon pardicolor] 
ENSG00000198805(PNP)	--	52.85476158	1393	48.3090697	1292	51.71118258	1372	67.59102847	1786	67.02226878	1747	59.72380997	1569	0.888751848	0.327384982	normal	0.711694567	0.413429408	normal	0.969229463	0.185082528	normal	0.058098318	0.309150159	normal	[F]	Nucleotide transport and metabolism	Molecular Function: catalytic activity (GO:0003824);; Biological Process: nucleoside metabolic process (GO:0009116);; 	"K03783|0|hsa:4860|PNP, NP, PRO1837, PUNP; purine nucleoside phosphorylase (EC:2.4.2.1); K03783 purine-nucleoside phosphorylase [EC:2.4.2.1] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	[F]	Nucleotide transport and metabolism	Phosphorylase superfamily	Purine nucleoside phosphorylase GN=PNP OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: purine nucleoside phosphorylase [Oryctolagus cuniculus]
ENSG00000198807(PAX9)	--	0.948961265	62	0.595094652	41	1.251233391	81	1.454401771	101	1.313025168	87	1.642892572	109	0.66093656	0.66025176	normal	0.098690675	1.037135429	normal	0.903432834	0.413367172	normal	0.110377206	0.670661937	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09382|0|hsa:5083|PAX9, STHAG3; paired box 9; K09382 paired box protein 1/9 (A)"	--	[K]	Transcription	'Paired box' domain;; Homeodomain-like domain	Paired box protein Pax-9 GN=PAX9 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: paired box protein Pax-9 isoform X2 [Galeopterus variegatus]
ENSG00000198812(LRRC10)	--	0	0	0	0	0	0	0	0	0	0	0.0219002	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 10 GN=LRRC10 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 10-like [Sus scrofa] 
ENSG00000198814(GK)	--	2.045385878	72	2.16671624	96	1.401070405	77	3.213976383	150	2.805935895	127	3.372325171	162	0.009330422	1.012779279	up	0.905393546	0.377116029	normal	0.003357313	1.050235436	up	0.014366387	0.820191488	normal	[C]	Energy production and conversion	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K00864|0|mcf:102136861|GK; glycerol kinase; K00864 glycerol kinase [EC:2.7.1.30] (A)	Glycerolipid metabolism (ko00561);; PPAR signaling pathway (ko03320)	[G]	Carbohydrate transport and metabolism	"FGGY family of carbohydrate kinases, N-terminal domain;; FGGY family of carbohydrate kinases, C-terminal domain"	Glycerol kinase GN=GK OS=Homo sapiens (Human) PE=1 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: glycerol kinase isoform X3 [Oryctolagus cuniculus]
ENSG00000198815(FOXJ3)	--	13.54627624	1100	13.99792783	1066	11.768882	938	10.47835937	856	12.14340546	966	10.16629293	884	0.740857943	-0.392030464	normal	0.967018563	-0.163295423	normal	0.974941198	-0.093677393	normal	0.250812331	-0.219247356	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09403|0|bacu:103018870|FOXJ3; forkhead box J3; K09403 forkhead box protein J2/3 (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein J3 GN=FOXJ3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: forkhead box protein J3 isoform X1 [Galeopterus variegatus] 
ENSG00000198818(SFT2D1)	--	45.72243	538	39.14679	463	43.1406	479	45.16983	532	36.1489	424	41.39353	484	0.971454362	-0.046877561	normal	0.958564629	-0.147869571	normal	0.971449705	0.006669003	normal	0.85524416	-0.061151721	normal	--	--	Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Got1/Sft2-like family	Vesicle transport protein SFT2A OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle transport protein SFT2A isoform X1 [Mustela putorius furo]
ENSG00000198821(CD247)	--	0.034585328	1	0.0322942	1	0	0	0.034148432	1	0	0	0.098381209	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transmembrane signaling receptor activity (GO:0004888);; Biological Process: cell surface receptor signaling pathway (GO:0007166);; Cellular Component: membrane (GO:0016020);; 	"K06453|5.64341e-117|ptr:748272|CD247; CD247 molecule; K06453 CD3Z antigen, zeta polypeptide (A)"	Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; Chagas disease (American trypanosomiasis) (ko05142)	--	--	Immunoreceptor tyrosine-based activation motif;; T-cell surface glycoprotein CD3 zeta chain	T-cell surface glycoprotein CD3 zeta chain (Precursor) GN=CD247 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: T-cell surface glycoprotein CD3 zeta chain [Orycteropus afer afer]
ENSG00000198824(CHAMP1)	--	11.421499	754	12.54076645	805	12.17786	782	11.686195	765	10.080721	666	9.117849	603	0.976298544	-0.009916978	normal	0.901545177	-0.294284317	normal	0.763444469	-0.382457304	normal	0.273539979	-0.224741295	normal	--	--	--	--	--	--	--	--	Chromosome alignment-maintaining phosphoprotein 1 GN=CHAMP1 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: chromosome alignment-maintaining phosphoprotein 1 [Oryctolagus cuniculus]
ENSG00000198825(INPP5F)	--	7.405980025	608	6.342117132	502	7.28008054	562	5.352156002	483	4.488567452	363	3.946196272	327	0.808505556	-0.361851801	normal	0.482374408	-0.48740947	normal	0.002831507	-0.786760965	normal	0.009995217	-0.533767114	normal	[T]	Signal transduction mechanisms	Molecular Function: phosphoric ester hydrolase activity (GO:0042578);; 	--	--	[I]	Lipid transport and metabolism	SacI homology domain;; Inositol phosphatase	Phosphatidylinositide phosphatase SAC2 GN=INPP5F OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: phosphatidylinositide phosphatase SAC2 [Sus scrofa]
ENSG00000198826(ARHGAP11A)	--	34.3268502	3007	33.12496821	2948	34.84411475	3009	36.00031416	3364	33.79309509	2995	31.26815318	2725	0.986779315	0.130957291	normal	0.989872318	0.001392212	normal	0.983986169	-0.151239409	normal	0.998125709	-0.002629594	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	RhoGAP domain	Rho GTPase-activating protein 11A GN=ARHGAP11A OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 11A [Galeopterus variegatus]
ENSG00000198829(SUCNR1)	--	0.0904025	5	0.0549772	3	0.146845	7	0.536282	30	1.62214	90	0.51736	29	0.027272199	2.243982596	normal	1.11E-16	4.324379192	up	0.175367576	1.834422156	normal	0.039278187	3.292796176	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K10042|0|hsa:56670|SUCNR1, GPR91; succinate receptor 1; K10042 succinate receptor 1 (A)"	cAMP signaling pathway (ko04024)	--	--	7 transmembrane receptor (rhodopsin family)	Succinate receptor 1 GN=SUCNR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: succinate receptor 1 [Galeopterus variegatus]
ENSG00000198830(HMGN2)	--	133.97972	2495	165.50493	3113	148.95897	2783	262.18209	4956	206.95595	3819	242.48247	4527	1.01E-06	0.958877402	normal	0.961162454	0.273342721	normal	0.006395583	0.693324707	normal	0.000178308	0.643084906	normal	--	--	--	--	--	--	--	HMG14 and HMG17	Putative Dresden prostate carcinoma protein 2 GN=HMGN2P46 OS=Homo sapiens (Human) PE=5 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: putative Dresden prostate carcinoma protein 2 [Equus przewalskii]
ENSG00000198832(SELENOM)	--	37.2553391	279	34.1794283	259	34.2424256	265	24.428248	188	36.993241	275	26.7338215	203	0.280639076	-0.596335707	normal	0.96454069	0.064686393	normal	0.820041893	-0.390251784	normal	0.326662251	-0.290688807	normal	--	--	--	--	--	--	--	Sep15/SelM redox domain	Selenoprotein M (Precursor) GN=SELM OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: selenoprotein M [Galeopterus variegatus]
ENSG00000198833(UBE2J1)	--	12.69545	822	13.38956	860	10.790616	687	13.38086	879	13.59179	883	14.26851	933	0.975897296	0.065773614	normal	0.977341863	0.016621376	normal	0.612523853	0.432455604	normal	0.44585178	0.164634361	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K10578|0|hsa:51465|UBE2J1, HSPC153, HSPC205, HSU93243, NCUBE-1, NCUBE1, UBC6, Ubc6p; ubiquitin-conjugating enzyme E2, J1 (EC:6.3.2.19); K10578 ubiquitin-conjugating enzyme E2 J1 [EC:6.3.2.19] (A)"	Ubiquitin mediated proteolysis (ko04120);; Protein processing in endoplasmic reticulum (ko04141);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2 J1 GN=UBE2J1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 J1 [Galeopterus variegatus]
ENSG00000198835(GJC2)	--	0.493233	17	0.598069	22	0.398552	14	0.281706	10	0.645753	22	0.226766	8	--	--	--	0.987199937	-0.020048445	normal	--	--	--	--	--	--	--	--	--	"K07619|0|hsa:57165|GJC2, CX46.6, Cx47, GJA12, HLD2, LMPH1C, PMLDAR, SPG44; gap junction protein, gamma 2, 47kDa; K07619 gap junction protein, alpha 12 (A)"	--	--	--	Connexin;; Gap junction channel protein cysteine-rich domain	Gap junction gamma-2 protein GN=GJC2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gap junction gamma-2 protein [Odobenus rosmarus divergens]
ENSG00000198836(OPA1)	--	20.56381845	1735	21.44658041	1666	23.57365788	1886	21.08261294	1816	23.35845713	1909	19.3951791	1703	0.985402576	0.034966011	normal	0.974199507	0.174853782	normal	0.977468227	-0.155411479	normal	0.95908328	0.016833713	normal	--	--	--	K17079|0|mcf:102117668|OPA1; optic atrophy 1 (autosomal dominant); K17079 optic atrophy protein 1 [EC:3.6.5.5] (A)	--	[R]	General function prediction only	Dynamin family;; 50S ribosome-binding GTPase	"Dynamin-like 120 kDa protein, form S1 (Precursor) GN=OPA1 OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: dynamin-like 120 kDa protein, mitochondrial isoform X1 [Condylura cristata]"
ENSG00000198837(DENND4B)	--	11.5742993	1207	12.58958	1359	11.59853185	1288	10.40564919	1118	9.798614423	1053	14.4188339	1509	0.973015525	-0.141150991	normal	0.767473053	-0.388973365	normal	0.958926384	0.21992997	normal	0.802894876	-0.086985248	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; dDENN domain;; uDENN domain	DENN domain-containing protein 4B GN=DENND4B OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 4B [Galeopterus variegatus]
ENSG00000198838(RYR3)	--	0.23112296	10	0.468127835	19	0.146252024	8	0.054741129	4	0.479952792	19	0.468370526	20	--	--	--	--	--	--	0.925500344	1.169955837	normal	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: ryanodine-sensitive calcium-release channel activity (GO:0005219);; Molecular Function: calcium channel activity (GO:0005262);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Biological Process: cellular calcium ion homeostasis (GO:0006874);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: transmembrane transport (GO:0055085);; Biological Process: calcium ion transmembrane transport (GO:0070588);; 	"K04963|0|hsa:6263|RYR3, RYR-3; ryanodine receptor 3; K04963 ryanodine receptor 3 (A)"	Calcium signaling pathway (ko04020);; Circadian entrainment (ko04713);; Oxytocin signaling pathway (ko04921);; Salivary secretion (ko04970);; Alzheimer's disease (ko05010)	[T]	Signal transduction mechanisms	"RyR domain;; RIH domain;; Ryanodine Receptor TM 4-6;; SPRY domain;; Inositol 1,4,5-trisphosphate/ryanodine receptor;; MIR domain;; RyR and IP3R Homology associated;; Ion transport protein"	Ryanodine receptor 3 GN=RYR3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: ryanodine receptor 3 isoform X1 [Oryctolagus cuniculus]
ENSG00000198839(ZNF277)	--	15.50029672	633	11.52235546	517	14.17136164	554	12.52959948	577	12.05006208	537	11.50964637	511	0.959444258	-0.164049171	normal	0.971120538	0.033235859	normal	0.964902032	-0.124500153	normal	0.756016305	-0.090072273	normal	--	--	--	--	--	[K]	Transcription	C2H2 type zinc-finger (2 copies);; Zinc-finger of C2H2 type;; Zinc-finger double-stranded RNA-binding	Zinc finger protein 277 GN=ZNF277 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 277 isoform X1 [Equus caballus]
ENSG00000198840(MT-ND3)	--	7411.56	6291	7015.84	5890	6319.74	5596	6437.99	6635	5851.39	5114	5800.52	5417	0.994420134	0.045963909	normal	0.982549382	-0.225179922	normal	0.993497183	-0.055178157	normal	0.778219434	-0.072507597	normal	--	--	--	"K03880|2.05468e-18|hsa:4537|ND3, MTND3, MT-ND3; NADH dehydrogenase, subunit 3 (complex I); K03880 NADH-ubiquinone oxidoreductase chain 3 [EC:1.6.5.3] (A)"	Oxidative phosphorylation (ko00190);; Parkinson's disease (ko05012)	[C]	Energy production and conversion	--	NADH-ubiquinone oxidoreductase chain 3 GN=MT-ND3 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	NADH dehydrogenase subunit 3 [Echinops telfairi] 
ENSG00000198843(SELENOT)	--	36.59829355	1320	36.28029154	1407	36.6563551	1234	52.207176	2032	44.65931737	1718	39.02292	1412	0.070670711	0.590971929	normal	0.94195872	0.266421642	normal	0.967191164	0.185893133	normal	0.124274986	0.359588964	normal	--	--	--	--	--	[R]	General function prediction only	Rdx family	Selenoprotein T (Precursor) GN=SELT OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: selenoprotein T [Eptesicus fuscus]
ENSG00000198846(TOX)	--	0.0285595	2	0.0725936	5	0	0	1.00328	70	0.662724	46	0.254399	18	3.58E-13	4.314505093	up	1.10E-05	2.848468206	up	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	HMG (high mobility group) box;; HMG-box domain	Thymocyte selection-associated high mobility group box protein TOX GN=TOX OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: thymocyte selection-associated high mobility group box protein TOX [Orycteropus afer afer]
ENSG00000198848(CES1)	--	0.02892888	1	0	0	0.175553032	0	0.680581	27	1.061021243	39	1.096081395	41	0.000579503	3.471273636	up	4.13E-08	4.733279122	up	1.09E-08	4.809082242	up	8.84E-13	6.7194977	up	[I]	Lipid transport and metabolism	Biological Process: metabolic process (GO:0008152);; Molecular Function: hydrolase activity (GO:0016787);; 	"K01044|0|hsa:1066|CES1, ACAT, CE-1, CEH, CES2, HMSE, HMSE1, PCE-1, REH, SES1, TGH, hCE-1; carboxylesterase 1 (EC:3.1.1.1 3.1.1.56); K01044 carboxylesterase 1 [EC:3.1.1.1] (A)"	Drug metabolism - other enzymes (ko00983)	[R]	General function prediction only	Carboxylesterase family;; alpha/beta hydrolase fold	Liver carboxylesterase 1 (Precursor) GN=CES1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: liver carboxylesterase 1 [Ailuropoda melanoleuca]
ENSG00000198853(RUSC2)	--	12.15646167	1454	14.5335075	1767	15.63833066	1910	13.63634256	1621	13.6134337	1611	19.1152944	2306	0.978754517	0.125898524	normal	0.976405612	-0.154633438	normal	0.951488023	0.263338411	normal	0.84673118	0.090253869	normal	--	--	--	--	--	--	--	RUN domain;; Variant SH3 domain	Iporin GN=RUSC2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: iporin [Galeopterus variegatus]
ENSG00000198855(FICD)	--	3.39847	209	3.5062	217	3.7872454	217	3.39069	208	2.926	179	5.10164	314	0.966449772	-0.03747552	normal	0.913339729	-0.296880023	normal	0.475025692	0.521738902	normal	0.859917786	0.10464764	normal	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Fic/DOC family	Adenosine monophosphate-protein transferase FICD GN=FICD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: adenosine monophosphate-protein transferase FICD isoform X3 [Canis lupus familiaris] 
ENSG00000198856(OSTC)	--	64.40273236	882	63.679812	869	56.82546166	766	79.412218	1087	78.777808	1065	78.216568	1063	0.925727212	0.270244453	normal	0.925383205	0.271571264	normal	0.488179414	0.463653466	normal	0.05214069	0.331625581	normal	--	--	--	--	--	[S]	Function unknown	OST3 / OST6 family	Oligosaccharyltransferase complex subunit OSTC GN=OSTC OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	Oligosaccharyltransferase complex subunit OSTC [Pteropus alecto]
ENSG00000198858(R3HDM4)	--	23.764757	684	15.642739	459	19.7816516	590	20.401916	589	20.525885	590	17.27492	498	0.931742104	-0.24596486	normal	0.847799083	0.339804498	normal	0.926823884	-0.252156262	normal	0.862752451	-0.068890547	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	--	--	R3H-associated N-terminal domain;; R3H domain	R3H domain-containing protein 4 GN=R3HDM4 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: R3H domain-containing protein 4 isoform X1 [Sus scrofa]
ENSG00000198860(TSEN15)	--	26.348013	665	30.5646	729	23.748916	583	24.92301219	647	26.626137	671	23.38243	601	0.972496146	-0.070256316	normal	0.965252676	-0.140728201	normal	0.973068782	0.035487	normal	0.829044036	-0.064655831	normal	--	--	--	K15324|1.4732e-108|ggo:101137640|TSEN15; tRNA-splicing endonuclease subunit Sen15 isoform 1; K15324 tRNA-splicing endonuclease subunit Sen15 (A)	--	--	--	Sen15 protein	tRNA-splicing endonuclease subunit Sen15 GN=TSEN15 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: tRNA-splicing endonuclease subunit Sen15-like [Leptonychotes weddellii]
ENSG00000198862(LTN1)	--	7.1323793	891	7.427473952	920	8.480764363	1032	7.880210735	992	7.757304339	967	7.12750514	890	0.972206061	0.123879918	normal	0.977422348	0.050374701	normal	0.95050749	-0.221507297	normal	0.958484282	-0.018225153	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	FANCL C-terminal domain;; Anaphase-promoting complex subunit 11 RING-H2 finger	E3 ubiquitin-protein ligase listerin GN=HSPC087 OS=Homo sapiens (Human) PE=1 SV=6	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase listerin [Equus przewalskii]
ENSG00000198863(RUNDC1)	--	10.15728724	770	11.27697487	863	11.59657092	902	14.58748882	1119	13.83756122	1058	14.401394	1087	0.305634247	0.507602914	normal	0.924893055	0.272049418	normal	0.932534439	0.260462823	normal	0.042378306	0.343518271	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	RUN domain	RUN domain-containing protein 1 GN=RUNDC1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: RUN domain-containing protein 1 [Canis lupus familiaris]
ENSG00000198870(STKLD1)	--	0.184579	11	0.0980299	6	0.0484114	2	0.0503173	3	0.0491535	2	0.116593	7	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17546|0|hsa:169436|STKLD1, C9orf96, SgK071, Sk521; serine/threonine kinase-like domain containing 1; K17546 probable inactive protein kinase-like protein SgK071 (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Serine/threonine kinase-like domain-containing protein STKLD1 GN=STKLD1 OS=Homo sapiens (Human) PE=2 SV=4	T	Signal transduction mechanisms	PREDICTED: probable inactive protein kinase-like protein SgK071 [Ceratotherium simum simum]
ENSG00000198873(GRK5)	--	4.432075	261	3.10147	180	3.800957	231	7.476881	451	5.59834	329	4.568473	273	0.009951233	0.754826491	normal	0.005093541	0.843348404	normal	0.937429068	0.231322127	normal	0.105216913	0.62535032	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08291|0|hsa:2869|GRK5, GPRK5; G protein-coupled receptor kinase 5 (EC:2.7.11.16); K08291 G protein-coupled receptor kinase [EC:2.7.11.16] (A)"	Chemokine signaling pathway (ko04062);; Endocytosis (ko04144);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Regulator of G protein signaling domain	G protein-coupled receptor kinase 5 GN=GRK5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: G protein-coupled receptor kinase 5-like isoform X1 [Tupaia chinensis]
ENSG00000198874(TYW1)	--	8.070014077	523	9.930412439	527	8.199664466	566	9.756535001	600	10.51933226	642	9.038219096	624	0.957886525	0.166861388	normal	0.92136912	0.262659954	normal	0.965096269	0.132116224	normal	0.42617991	0.186613777	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: FMN binding (GO:0010181);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	"K15449|0|hsa:55253|TYW1, RSAFD1, TYW1A, YPL207W; tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) (EC:4.1.3.44); K15449 tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] (A)"	--	[C]	Energy production and conversion	Radical SAM superfamily;; Flavodoxin;; Wyosine base formation	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase GN=TYW1 OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	"PREDICTED: tRNA wybutosine-synthesizing protein 1 homolog, partial [Ceratotherium simum simum]"
ENSG00000198876(DCAF12)	--	15.44511452	960	18.67311283	1160	15.97781739	985	21.76413762	1354	21.80481413	1346	21.9558202	1368	0.482262027	0.464660284	normal	0.964314582	0.192893425	normal	0.482369359	0.464972775	normal	0.021718864	0.368397653	normal	--	--	--	K11803|0|pon:100459173|DCAF12; DDB1 and CUL4 associated factor 12; K11803 WD repeat-containing protein 40A (A)	--	--	--	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 12 GN=DCAF12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 12 isoform 1 [Sus scrofa]
ENSG00000198879(SFMBT2)	--	5.615908899	868	4.63357329	628	5.638466206	826	6.100255678	943	8.250750391	1235	7.651250294	1106	0.975169412	0.088580015	normal	7.48E-06	0.952582411	normal	0.682081314	0.41219186	normal	0.034630331	0.479697616	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	mbt repeat;; Protein of unknown function (DUF3588);; SAM domain (Sterile alpha motif);; Sterile alpha motif (SAM)/Pointed domain	Scm-like with four MBT domains protein 2 GN=SFMBT2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: scm-like with four MBT domains protein 2-like isoform X1 [Tupaia chinensis] 
ENSG00000198881(ASB12)	--	0	0	0.0526132	1	0	0	0	0	0.0519278	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10334|0|hsa:142689|ASB12; ankyrin repeat and SOCS box containing 12; K10334 ankyrin repeat and SOCS box protein 12 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 12 GN=ASB12 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 12 [Trichechus manatus latirostris]
ENSG00000198886(MT-ND4)	--	34990.7	184709	36842.5	175511	35201.4	178168	25877.93	133591	26621.36	130386	26597.66	138667	0.931432869	-0.498258713	normal	0.97373493	-0.450194521	normal	0.993160861	-0.369901622	normal	0.070478511	-0.440240336	normal	[C]	Energy production and conversion	--	"K03881|4.92471e-179|hsa:4538|ND4, MTND4, MT-ND4, LHON; NADH dehydrogenase, subunit 4 (complex I); K03881 NADH-ubiquinone oxidoreductase chain 4 [EC:1.6.5.3] (A)"	Oxidative phosphorylation (ko00190);; Parkinson's disease (ko05012)	[C]	Energy production and conversion	"NADH-ubiquinone oxidoreductase chain 4, amino terminus"	NADH-ubiquinone oxidoreductase chain 4 GN=MT-ND4 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	NADH dehydrogenase subunit 4 [Vicugna vicugna] 
ENSG00000198887(SMC5)	--	10.670734	1168	10.47788907	1151	10.74648571	1160	10.25105087	1141	11.209563	1211	9.041246548	999	0.979702866	-0.064487914	normal	0.980081295	0.051818097	normal	0.952126277	-0.223545309	normal	0.762208716	-0.075587362	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	--	--	[BDL]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning;; Replication, recombination and repair"	RecF/RecN/SMC N terminal domain;; AAA domain;; AAA domain	Structural maintenance of chromosomes protein 5 GN=SMC5 OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: structural maintenance of chromosomes protein 5 isoform X2 [Oryctolagus cuniculus]
ENSG00000198888(MT-ND1)	--	6971.18	76031	6390.34	66486	6264.09	66723	5422.01	60137	4961.88	55026	5296.93	59465	0.986455066	-0.36915872	normal	0.994776702	-0.29435631	normal	0.998474137	-0.174430634	normal	0.240621618	-0.282222096	normal	[C]	Energy production and conversion	--	"K03878|9.69064e-109|hsa:4535|ND1, MTND1, MT-ND1; NADH dehydrogenase, subunit 1 (complex I); K03878 NADH-ubiquinone oxidoreductase chain 1 [EC:1.6.5.3] (A)"	Oxidative phosphorylation (ko00190);; Parkinson's disease (ko05012)	[C]	Energy production and conversion	NADH dehydrogenase	NADH-ubiquinone oxidoreductase chain 1 GN=MT-ND1 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	NADH dehydrogenase subunit 1 [Camelus bactrianus] 
ENSG00000198889(DCAF12L1)	--	0	0	0	0	0	0	0.0194536	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	DDB1- and CUL4-associated factor 12-like protein 1 GN=DCAF12L1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: DDB1- and CUL4-associated factor 12-like protein 2-like [Odobenus rosmarus divergens]
ENSG00000198890(PRMT6)	--	0.0236339	1	0	0	0.0452185	1	0.0233145	1	0.0229392	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K11437|0|ptr:457073|PRMT6, HRMT1L6; protein arginine methyltransferase 6; K11437 protein arginine N-methyltransferase 6 [EC:2.1.1.-] (A)"	--	[OKT]	"Posttranslational modification, protein turnover, chaperones;; Transcription;; Signal transduction mechanisms"	Methyltransferase domain;; Ribosomal protein L11 methyltransferase (PrmA);; Methyltransferase domain;; PRMT5 arginine-N-methyltransferase;; Methyltransferase domain;; Methyltransferase small domain;; Protein of unknown function (DUF1698);; Met-10+ like-protein	Protein arginine N-methyltransferase 6 GN=PRMT6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein arginine N-methyltransferase 6 [Loxodonta africana]
ENSG00000198898(CAPZA2)	--	61.28413132	2660	62.74564234	2705	61.37663328	2558	65.48675814	2834	70.37813328	2739	66.27490337	2685	0.988768641	0.060547365	normal	0.989193238	-0.003403995	normal	0.988344748	0.061578845	normal	0.88850861	0.038303999	normal	--	--	Cellular Component: F-actin capping protein complex (GO:0008290);; Biological Process: barbed-end actin filament capping (GO:0051016);; 	"K10364|0|ptr:736736|CAPZA2; capping protein (actin filament) muscle Z-line, alpha 2; K10364 capping protein (actin filament) muscle Z-line, alpha (A)"	--	[Z]	Cytoskeleton	F-actin capping protein alpha subunit	F-actin-capping protein subunit alpha-2 GN=CAPZA2 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: F-actin-capping protein subunit alpha-2 [Galeopterus variegatus]
ENSG00000198899(MT-ATP6)	--	108984.1	241623	102705.6	217129	95817.8	214440	78932.2	209513	88154.2	217115	82871.6	196713	0.99913826	-0.236548673	normal	0.999706121	-0.021519433	normal	0.999579537	-0.132772201	normal	0.715293745	-0.132431897	normal	[C]	Energy production and conversion	--	"K02126|1.14033e-89|hsa:4508|ATP6, ATPase6, MTATP6, MT-ATP6, RP; ATP synthase F0 subunit 6; K02126 F-type H+-transporting ATPase subunit a (A)"	Oxidative phosphorylation (ko00190);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	ATP synthase A chain	ATP synthase subunit a GN=MT-ATP6 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	ATP6 gene product (mitochondrion) [Lasiurus borealis] 
ENSG00000198900(TOP1)	--	37.2315	3234	32.09	2774	38.3553	3290	33.2061	2897	31.6458	2737	31.6155	2746	0.980188826	-0.189497072	normal	0.988940624	-0.040776531	normal	0.958780321	-0.268911906	normal	0.370928811	-0.171138685	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA topoisomerase type I activity (GO:0003917);; Cellular Component: chromosome (GO:0005694);; Biological Process: DNA topological change (GO:0006265);; 	K03163|0|fca:101093174|TOP1; topoisomerase (DNA) I; K03163 DNA topoisomerase I [EC:5.99.1.2] (A)	--	[L]	"Replication, recombination and repair"	"Eukaryotic DNA topoisomerase I, DNA binding fragment;; Eukaryotic DNA topoisomerase I, catalytic core;; C-terminal topoisomerase domain"	DNA topoisomerase 1 GN=TOP1 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	DNA topoisomerase 1 [Pteropus alecto]
ENSG00000198901(PRC1)	--	71.2027848	3999	59.08652022	3528	72.45605525	3771	69.96239718	3940	71.778079	3782	53.005593	3030	0.991673019	-0.052255688	normal	0.990194091	0.078839601	normal	0.928361538	-0.323775642	normal	0.687281448	-0.093351878	normal	--	--	--	K16732|0|ptr:453656|PRC1; protein regulator of cytokinesis 1; K16732 protein regulator of cytokinesis 1 (A)	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Microtubule associated protein (MAP65/ASE1 family)	Protein regulator of cytokinesis 1 OS=Homo sapiens (Human) PE=1 SV=2	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: protein regulator of cytokinesis 1 isoform X1 [Leptonychotes weddellii]
ENSG00000198908(BHLHB9)	--	3.282128481	247	5.002622927	356	4.128100773	297	3.72205963	278	2.820542176	207	3.951521	286	0.958409672	0.138926714	normal	0.008564587	-0.799163959	normal	0.966069668	-0.062415337	normal	0.483237391	-0.24453194	normal	--	--	--	--	--	--	--	Armadillo-like	Protein BHLHb9 GN=BHLHB9 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein BHLHb9 [Galeopterus variegatus] 
ENSG00000198909(MAP3K3)	--	6.406062222	623	7.77063661	766	6.783768734	672	8.124024167	769	6.971465041	659	6.90258431	664	0.916908488	0.272313818	normal	0.937704131	-0.237985367	normal	0.974685274	-0.025511676	normal	1	-0.000249726	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K04421|0|mcf:102132095|MAP3K3; mitogen-activated protein kinase kinase kinase 3; K04421 mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25] (A)	MAPK signaling pathway (ko04010);; Neurotrophin signaling pathway (ko04722);; GnRH signaling pathway (ko04912);; HTLV-I infection (ko05166)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; PB1 domain	Mitogen-activated protein kinase kinase kinase 3 GN=MAP3K3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: mitogen-activated protein kinase kinase kinase 3 [Physeter catodon]
ENSG00000198910(L1CAM)	--	6.612571722	535	3.356977008	359	3.886602449	439	2.913188017	323	2.71126484	268	1.40196033	159	0.006024852	-0.756010746	normal	0.682923193	-0.441018885	normal	6.61E-11	-1.464736664	down	0.021097641	-0.852799927	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06550|0|hsa:3897|L1CAM, CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1; L1 cell adhesion molecule; K06550 L1 cell adhesion molecule (A)"	Axon guidance (ko04360);; Cell adhesion molecules (CAMs) (ko04514)	[T]	Signal transduction mechanisms	Immunoglobulin I-set domain;; Fibronectin type III domain;; Immunoglobulin domain;; Immunoglobulin domain;; Bravo-like intracellular region;; Immunoglobulin domain;; Immunoglobulin V-set domain;; CD80-like C2-set immunoglobulin domain	Neural cell adhesion molecule L1 (Precursor) GN=L1CAM OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neural cell adhesion molecule L1 isoform X2 [Oryctolagus cuniculus] 
ENSG00000198911(SREBF2)	--	48.278857	4979	46.897183	4866	45.115854	4715	29.5889729	3022	31.027505	3169	48.179881	4970	0.001192019	-0.750883839	normal	0.033846542	-0.639886772	normal	0.992567032	0.067675495	normal	0.185105842	-0.403311755	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09107|0|hsa:6721|SREBF2, SREBP-2, SREBP2, bHLHd2; sterol regulatory element binding transcription factor 2; K09107 sterol regulatory element-binding transcription factor 2 (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Processed sterol regulatory element-binding protein 2 GN=SREBF2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: sterol regulatory element-binding protein 2 [Tupaia chinensis]
ENSG00000198912(C1orf174)	--	9.31584	282	10.332077	309	10.07573	306	9.768336	295	10.285318	308	11.62722	352	0.967134743	0.034006379	normal	0.966725522	-0.025975712	normal	0.947866855	0.192862983	normal	0.85979673	0.06977486	normal	--	--	--	--	--	--	--	--	UPF0688 protein C1orf174 GN=C1orf174 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: UPF0688 protein C1orf174 homolog [Tupaia chinensis]
ENSG00000198914(POU3F3)	--	0.0187828	1	0	0	0	0	0.0370926	2	0.035931	1	0.0549518	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09365|0|hsa:5455|POU3F3, BRN1, OTF8; POU class 3 homeobox 3; K09365 POU domain transcription factor, class 3 (A)"	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 3, transcription factor 3 GN=POU3F3 OS=Homo sapiens (Human) PE=2 SV=2"	K	Transcription	"PREDICTED: POU domain, class 3, transcription factor 3 [Odobenus rosmarus divergens]"
ENSG00000198915(RASGEF1A)	--	1.72817348	108	1.556649985	77	1.301414878	79	2.1228409	135	2.317434893	134	2.751859231	182	0.938570738	0.287432492	normal	0.245562545	0.766332649	normal	0.00018945	1.180416364	up	0.024537261	0.752078244	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif	Ras-GEF domain-containing family member 1A GN=RASGEF1A OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: ras-GEF domain-containing family member 1A [Camelus ferus] 
ENSG00000198917(SPOUT1)	--	12.00134	558	8.294506454	519	8.60535	554	10.923502	554	9.902806677	544	7.33143	476	0.972091637	-0.041097839	normal	0.970748173	0.046313739	normal	0.938678752	-0.226547992	normal	0.814970207	-0.072866536	normal	[S]	Function unknown	--	"K09142|0|hsa:51490|C9orf114, CENP-32, HSPC109; chromosome 9 open reading frame 114; K09142 hypothetical protein (A)"	--	[S]	Function unknown	Putative RNA methyltransferase	Putative methyltransferase C9orf114 {ECO:0000305} GN=C9orf114 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: putative methyltransferase C9orf114 homolog [Felis catus]
ENSG00000198918(RPL39)	--	2601.34	4882	2832.83	5286	2723.1	5292	3212.4	6950	2911.94	5508	3094.58	6200	0.589491104	0.478581608	normal	0.993408838	0.03791495	normal	0.983860365	0.220105544	normal	0.165315688	0.249671311	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02924|1.38923e-28|bom:102269286|60S ribosomal protein L39-like; K02924 large subunit ribosomal protein L39e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal L39 protein	60S ribosomal protein L39 GN=RPL39 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 60S ribosomal protein L39 [Ceratotherium simum simum]
ENSG00000198919(DZIP3)	--	9.632021096	941	8.367249427	735	10.23323645	869	5.293411516	528	6.836278828	548	8.368826911	816	0.000122805	-0.862580787	normal	0.593668909	-0.443932929	normal	0.973478	-0.098900818	normal	0.139291545	-0.447524873	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K10642|0|hsa:9666|DZIP3, PPP1R66, UURF2, hRUL138; DAZ interacting zinc finger protein 3; K10642 E3 ubiquitin-protein ligase DZIP3 [EC:6.3.2.19] (A)"	--	--	--	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase DZIP3 GN=DZIP3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase DZIP3 isoform X1 [Equus caballus] 
ENSG00000198920(KIAA0753)	--	7.400756623	712	10.1595	833	10.00427896	748	10.20096304	863	10.08375305	846	10.02408375	853	0.935203671	0.246167979	normal	0.977001718	0.000912965	normal	0.95976487	0.180873367	normal	0.545592236	0.138716191	normal	--	--	Biological Process: centriole replication (GO:0007099);; 	--	--	--	--	--	Uncharacterized protein KIAA0753 GN=KIAA0753 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein KIAA0753 homolog [Galeopterus variegatus] 
ENSG00000198924(DCLRE1A)	--	8.013223171	596	7.323312423	537	8.403007455	607	8.78948975	656	7.47430848	553	8.349740844	625	0.968749183	0.107287541	normal	0.971781057	0.02087291	normal	0.97356034	0.033785277	normal	0.863485431	0.054641891	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K15340|0|hsa:9937|DCLRE1A, PSO2, SNM1, SNM1A; DNA cross-link repair 1A; K15340 DNA cross-link repair 1A protein (A)"	--	[L]	"Replication, recombination and repair"	DNA repair metallo-beta-lactamase;; Beta-lactamase superfamily domain	DNA cross-link repair 1A protein GN=DCLRE1A OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA cross-link repair 1A protein isoform X1 [Physeter catodon] 
ENSG00000198925(ATG9A)	--	28.82488846	1812	31.57487304	1796	29.56114601	1816	24.98413167	1418	21.17083346	1345	23.85419622	1366	0.785906869	-0.384188359	normal	0.62663396	-0.43817975	normal	0.682461464	-0.418694729	normal	0.006240859	-0.414868038	normal	--	--	--	"K17907|0|hsa:79065|ATG9A, APG9L1, MGD3208, mATG9; autophagy related 9A; K17907 autophagy-related protein 9 (A)"	--	[R]	General function prediction only	Autophagy protein Apg9	Autophagy-related protein 9A GN=ATG9A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	"PREDICTED: ATP-binding cassette sub-family B member 6, mitochondrial-like isoform X1 [Bubalus bubalis] "
ENSG00000198929(NOS1AP)	--	1.006490488	112	2.15979529	121	1.574714436	130	1.736766599	169	1.383163564	126	0.894411795	104	0.621833288	0.556439716	normal	0.967388201	0.036542564	normal	0.927150871	-0.325970929	normal	0.831204751	0.113885288	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K16513|0|mcc:720378|NOS1AP; nitric oxide synthase 1 (neuronal) adaptor protein; K16513 carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (A)	Circadian entrainment (ko04713)	[R]	General function prediction only	Phosphotyrosine interaction domain (PTB/PID)	Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein GN=NOS1AP OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform X1 [Vicugna pacos]
ENSG00000198930(CSAG1)	--	0	0	0	0	0	0	0.92599488	9	0	0	0.26861629	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative chondrosarcoma-associated gene 1 protein (Precursor) GN=CSAG1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	--
ENSG00000198931(APRT)	--	137.2773677	1642	134.6044405	1648	145.1000554	1782	136.4381801	1643	125.7840024	1442	128.674724	1548	0.984716669	-0.029925917	normal	0.962890117	-0.213861649	normal	0.965203981	-0.21119084	normal	0.44789556	-0.151885802	normal	[F]	Nucleotide transport and metabolism	Biological Process: nucleoside metabolic process (GO:0009116);; 	K00759|5.41652e-126|pps:100990412|APRT; adenine phosphoribosyltransferase; K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] (A)	Purine metabolism (ko00230)	[F]	Nucleotide transport and metabolism	Phosphoribosyl transferase domain	Adenine phosphoribosyltransferase GN=APRT OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	PREDICTED: adenine phosphoribosyltransferase isoform X2 [Balaenoptera acutorostrata scammoni]
ENSG00000198932(GPRASP1)	--	0.348968666	45	0.29264045	38	0.211981293	27	0.493170824	63	0.42069842	53	0.26714886	35	0.943296198	0.441796564	normal	0.950870153	0.443560769	normal	0.976817446	0.348898417	normal	0.495051374	0.433531804	normal	--	--	--	--	--	--	--	Armadillo-like	G-protein coupled receptor-associated sorting protein 1 GN=GPRASP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor-associated sorting protein 1 [Odobenus rosmarus divergens]
ENSG00000198933(TBKBP1)	--	6.2957	454	6.045498	423	6.480430641	449	5.254319618	332	6.378615	427	4.036030301	298	0.511061283	-0.480431285	normal	0.969421567	-0.007820324	normal	0.153001747	-0.597207856	normal	0.124274986	-0.348369387	normal	--	--	--	"K12652|2.46195e-168|hsa:9755|TBKBP1, ProSAPiP2, SINTBAD; TBK1 binding protein 1; K12652 TANK-binding kinase 1-binding protein (A)"	RIG-I-like receptor signaling pathway (ko04622)	--	--	TBD domain	TANK-binding kinase 1-binding protein 1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: TANK-binding kinase 1-binding protein 1 [Balaenoptera acutorostrata scammoni]
ENSG00000198934(MAGEE1)	--	4.50022	307	4.18101	285	5.13248	351	3.33868	226	3.85231	262	2.81291	192	0.631509083	-0.469994614	normal	0.956902494	-0.142035305	normal	0.001840151	-0.873489625	normal	0.042040972	-0.492921728	normal	--	--	--	--	--	[S]	Function unknown	MAGE family	Melanoma-associated antigen E1 GN=MAGEE1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: melanoma-associated antigen E1 [Oryctolagus cuniculus]
ENSG00000198937(CCDC167)	--	26.8048	227	26.8699	234	26.9589	237	19.4938	171	21.3535	179	19.921	172	0.771005445	-0.436114391	normal	0.813921274	-0.404973298	normal	0.704569696	-0.46725478	normal	0.129983792	-0.440279104	normal	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 167	Coiled-coil domain-containing protein 167 GN=CCDC167 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 167 [Ceratotherium simum simum]
ENSG00000198939(ZFP2)	--	0.103640626	4	0.026187663	1	0.043276454	1	0.051281066	2	0.025089651	0	0.12903136	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; Transposase zinc-ribbon domain;; Prokaryotic RING finger family 1;; XPA protein N-terminal;; TFIIH C1-like domain"	Zinc finger protein 2 homolog GN=ZFP2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: ZFP2 zinc finger protein [Panthera tigris altaica]
ENSG00000198944(SOWAHA)	--	0.105269	5	0.0414661	2	0.121429	5	0.188085	9	0.181773	8	0.165757	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein SOWAHA (Precursor) GN=SOWAHA OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: sosondowah ankyrin repeat domain family member A [Ceratotherium simum simum]
ENSG00000198945(L3MBTL3)	--	5.115280834	304	3.478026636	251	3.457413207	263	3.759178067	258	3.989208962	250	2.560647653	162	0.92105378	-0.266070789	normal	0.965808081	-0.027022691	normal	0.089346076	-0.702165081	normal	0.303140765	-0.310403487	normal	--	--	"Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	mbt repeat;; SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Lethal(3)malignant brain tumor-like protein 3 GN=L3MBTL3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: lethal(3)malignant brain tumor-like protein 3 isoform X1 [Galeopterus variegatus] 
ENSG00000198947(DMD)	--	0.062015101	4	0.069266868	3	0.014307924	0	0.092300155	5	0.106303694	2	0.1102181	5	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	"K10366|0|hsa:1756|DMD, BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, MRX85; dystrophin; K10366 dystrophin (A)"	Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414);; Viral myocarditis (ko05416)	[NTZ]	Cell motility;; Signal transduction mechanisms;; Cytoskeleton	"Spectrin repeat;; EF hand;; EF-hand;; Calponin homology (CH) domain;; Zinc finger, ZZ type;; WW domain;; CAMSAP CH domain"	Dystrophin GN=DMD OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: dystrophin-like isoform 1 [Ceratotherium simum simum]
ENSG00000198948(MFAP3L)	--	2.815628112	267	2.735860974	237	2.914147735	243	5.129580431	463	5.842559348	518	4.135092771	420	0.008405772	0.759980737	normal	1.76E-06	1.101766827	up	0.007466197	0.777416791	normal	5.47E-06	0.885853013	normal	--	--	--	--	--	--	--	Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Microfibrillar-associated protein 3-like (Precursor) GN=MFAP3L OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: microfibrillar-associated protein 3-like isoform X2 [Tupaia chinensis]
ENSG00000198951(NAGA)	--	8.1530092	460	8.879276	467	7.18116	428	7.2702313	405	7.04884662	401	6.209995332	332	0.942044097	-0.21378255	normal	0.930775127	-0.240405786	normal	0.80410087	-0.373217535	normal	0.249647076	-0.273666244	normal	--	--	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K01204|0|hsa:4668|NAGA, D22S674, GALB; N-acetylgalactosaminidase, alpha- (EC:3.2.1.49); K01204 alpha-N-acetylgalactosaminidase [EC:3.2.1.49] (A)"	Glycosphingolipid biosynthesis - globo series (ko00603);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	Melibiase	Alpha-N-acetylgalactosaminidase (Precursor) GN=NAGA OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: alpha-N-acetylgalactosaminidase isoform X2 [Equus caballus] 
ENSG00000198952(SMG5)	--	24.3194	2376	26.6293	2639	26.3374	2608	24.2982	2364	26.1372	2531	33.9514	3317	0.988036566	-0.038112356	normal	0.987232803	-0.081662611	normal	0.906785595	0.33846927	normal	0.802027024	0.087246395	normal	--	--	--	"K11125|0|hsa:23381|SMG5, EST1B, LPTS-RP1, LPTSRP1, SMG-5; SMG5 nonsense mediated mRNA decay factor; K11125 protein SMG5 (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Est1 DNA/RNA binding domain;; Telomerase activating protein Est1;; PIN domain	Protein SMG5 GN=SMG5 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: protein SMG5 [Ceratotherium simum simum]
ENSG00000198954(KIF1BP)	--	24.94921828	1108	25.6158861	1151	26.378587	1172	26.50417091	1187	24.12059507	1068	24.05908848	1071	0.979421183	0.068438095	normal	0.97352873	-0.129226426	normal	0.972986281	-0.138119025	normal	0.797203402	-0.066314038	normal	--	--	--	--	--	--	--	KIF-1 binding protein C terminal	KIF1-binding protein GN=KIAA1279 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: KIF1-binding protein [Equus caballus]
ENSG00000198959(TGM2)	--	158.7057112	14440	79.09009149	7199	179.74457	15919	297.10564	26690	270.4225609	24341	313.72697	28281	9.41E-05	0.855328376	normal	0	1.73588297	up	0.000326734	0.820732692	normal	2.92E-05	1.058209642	up	--	--	Molecular Function: protein-glutamine gamma-glutamyltransferase activity (GO:0003810);; Biological Process: peptide cross-linking (GO:0018149);; 	K05625|0|pps:100994169|TGM2; transglutaminase 2; K05625 transglutaminase 2 [EC:2.3.2.13] (A)	Huntington's disease (ko05016)	--	--	"Transglutaminase family, C-terminal ig like domain;; Transglutaminase family;; Transglutaminase-like superfamily"	Protein-glutamine gamma-glutamyltransferase 2 GN=TGM2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-glutamine gamma-glutamyltransferase 2 isoform X1 [Vicugna pacos]
ENSG00000198960(ARMCX6)	--	24.53754305	540	28.7137735	622	26.99998519	576	30.3228815	662	29.81300976	612	28.7105137	659	0.921502122	0.262364429	normal	0.972505159	-0.044699919	normal	0.95474434	0.185462663	normal	0.601492541	0.132132144	normal	--	--	--	--	--	--	--	Armadillo-like	Protein ARMCX6 GN=ARMCX6 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein ARMCX6 [Galeopterus variegatus]
ENSG00000198961(PJA2)	--	20.60856477	1729	19.71026915	1660	19.36184266	1597	23.252121	1963	19.95622316	1665	19.76199715	1653	0.978238647	0.152163084	normal	0.984644583	-0.017072093	normal	0.984388897	0.041392441	normal	0.805295518	0.061068786	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10634|0|hsa:9867|PJA2, Neurodap1, RNF131; praja ring finger 2, E3 ubiquitin protein ligase (EC:6.3.2.-); K10634 E3 ubiquitin-protein ligase Praja2 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase Praja-2 GN=PJA2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase Praja-2 [Ceratotherium simum simum]
ENSG00000198964(SGMS1)	--	10.93367019	621	11.20928091	597	11.68636966	630	13.7857302	766	13.1766662	759	14.6341616	766	0.917557455	0.271313585	normal	0.868930961	0.324212505	normal	0.916780092	0.273105696	normal	0.137261814	0.288892759	normal	--	--	--	K04714|0|mcf:102126212|SGMS1; sphingomyelin synthase 1; K04714 shingomyelin synthase [EC:2.7.8.27] (A)	Sphingolipid metabolism (ko00600);; Sphingolipid signaling pathway (ko04071)	[S]	Function unknown	PAP2 superfamily C-terminal;; PAP2 superfamily;; SAM domain (Sterile alpha motif)	Phosphatidylcholine:ceramide cholinephosphotransferase 1 GN=SGMS1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: phosphatidylcholine:ceramide cholinephosphotransferase 1 [Galeopterus variegatus] 
ENSG00000203326(ZNF525)	--	0.068633051	5	0.093808265	8	0.187481397	11	0.246109155	27	0.269948672	26	0.478940069	35	0.101683993	2.099847257	normal	0.595441976	1.513078007	normal	0.242534938	1.537417818	normal	0.002925731	1.854961093	up	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; BolA-like protein"	Zinc finger protein 845 GN=ZNF845 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 160-like isoform X2 [Galeopterus variegatus]
ENSG00000203485(INF2)	--	35.78651916	3613	40.67629712	3923	41.89696847	4150	44.32511796	4444	41.14214385	4155	39.4942177	3980	0.966483711	0.267726498	normal	0.99134306	0.061441568	normal	0.991460935	-0.068608816	normal	0.719950803	0.084865345	normal	--	--	Molecular Function: actin binding (GO:0003779);; Biological Process: cellular component organization (GO:0016043);; Molecular Function: Rho GTPase binding (GO:0017048);; Biological Process: actin cytoskeleton organization (GO:0030036);; 	--	--	--	--	Formin Homology 2 Domain;; Diaphanous FH3 Domain;; Diaphanous GTPase-binding Domain;; WH2 motif	Inverted formin-2 GN=INF2 OS=Homo sapiens (Human) PE=1 SV=2	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: inverted formin-2 [Equus caballus]
ENSG00000203499(FAM83H-AS1)	--	0.8465219	71	0.896181	83	0.56367956	52	0.641284	53	0.6460992	52	1.133572	94	0.932289439	-0.4415566	normal	0.711970943	-0.680223002	normal	0.357038463	0.827707493	normal	0.942238902	-0.070022304	normal	[R]	General function prediction only	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Putative IQ motif and ankyrin repeat domain-containing protein LOC642574 OS=Homo sapiens (Human) PE=5 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: putative IQ motif and ankyrin repeat domain-containing protein isoform X7 [Bos taurus]
ENSG00000203666(EFCAB2)	--	6.06576382	83	2.744675021	48	6.307165973	75	5.971978525	76	5.777879232	62	8.271096112	105	0.968957625	-0.154945408	normal	0.958449873	0.338404874	normal	0.875017384	0.469105868	normal	0.7286166	0.218400569	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	EF-hand domain;; EF-hand domain pair;; EF hand	EF-hand calcium-binding domain-containing protein 2 GN=EFCAB2 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	EF-hand calcium-binding domain-containing protein 2 [Bos taurus] 
ENSG00000203667(COX20)	--	20.293089	808	25.78989925	975	18.67530788	751	19.1214907	762	16.15355925	639	17.21091191	699	0.970771731	-0.115170991	normal	0.045335776	-0.629796621	normal	0.970248953	-0.111578943	normal	0.143000383	-0.292890996	normal	--	--	--	K18184|3.17998e-72|pps:100992118|COX20; cytochrome c oxidase protein 20 homolog; K18184 cytochrome c oxidase assembly protein subunit 20 (A)	--	--	--	Protein of unknown function (DUF3767)	Cytochrome c oxidase protein 20 homolog GN=COX20 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: cytochrome c oxidase protein 20 homolog [Ceratotherium simum simum]
ENSG00000203697(CAPN8)	--	0	0	0.118584299	6	0	0	0	0	0.110378816	1	0.024443248	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	"K08577|0|hsa:388743|CAPN8, nCL-2; calpain 8 (EC:3.4.22.53); K08577 calpain-8 [EC:3.4.22.-] (A)"	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III;; EF hand;; EF-hand domain;; EF-hand domain pair;; EF-hand domain pair"	Calpain-8 GN=CAPN8 OS=Homo sapiens (Human) PE=2 SV=3	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-8 [Ceratotherium simum simum]
ENSG00000203705(TATDN3)	--	5.278623657	182	5.362402726	158	4.362382157	163	5.814307468	207	4.931357213	152	5.848200753	185	0.957385569	0.153643307	normal	0.964484031	-0.076532877	normal	0.95546347	0.172855616	normal	0.849439103	0.091327455	normal	[L]	"Replication, recombination and repair"	"Molecular Function: hydrolase activity, acting on ester bonds (GO:0016788);; "	K03424|1.14976e-172|hsa:128387|TATDN3; TatD DNase domain containing 3; K03424 TatD DNase family protein [EC:3.1.21.-] (A)	--	[L]	"Replication, recombination and repair"	TatD related DNase	Putative deoxyribonuclease TATDN3 GN=TATDN3 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: putative deoxyribonuclease TATDN3 isoform X1 [Camelus bactrianus] 
ENSG00000203710(CR1)	--	0	0	0	0	0	0	0.016991392	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04011|0|hsa:1378|CR1, C3BR, C4BR, CD35, KN; complement component (3b/4b) receptor 1 (Knops blood group); K04011 complement component (3b/4b) receptor 1 (A)"	Complement and coagulation cascades (ko04610);; Hematopoietic cell lineage (ko04640);; Legionellosis (ko05134);; Leishmaniasis (ko05140);; Malaria (ko05144);; Tuberculosis (ko05152)	--	--	Sushi domain (SCR repeat);; Invasion protein B family	Complement receptor type 1 (Precursor) GN=CR1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: complement receptor type 2-like isoform 1 [Dasypus novemcinctus]
ENSG00000203722(RAET1G)	--	0.37744751	9	0.124121803	2	0.25666482	5	2.101159076	46	2.561488	53	1.450373853	38	0.001137972	2.145557751	up	2.03E-09	3.939588341	up	0.00047227	2.593895134	up	9.39E-08	3.076539767	up	--	--	--	"K07987|0|hsa:353091|RAET1G, ULBP5; retinoic acid early transcript 1G; K07987 retinoic acid early transcript 1 (A)"	Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2"	Retinoic acid early transcript 1G protein (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: NKG2D ligand 1-like [Equus caballus]
ENSG00000203724(C1orf53)	--	4.388702179	26	4.675280661	29	5.604600395	35	4.577220721	29	5.027561035	30	4.0836021	25	0.985497533	0.119993212	normal	0.984096849	0.026142688	normal	0.969382751	-0.469604154	normal	0.91179757	-0.120676995	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf53 GN=C1orf53 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf53 homolog [Orycteropus afer afer]
ENSG00000203727(SAMD5)	--	0.689492	61	0.906815	81	0.651979	57	1.02156	92	1.3479	120	1.34975	121	0.839972711	0.55063086	normal	0.776841031	0.537324441	normal	0.01533238	1.057981797	normal	0.064462578	0.721986822	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Sterile alpha motif domain-containing protein 5 GN=SAMD5 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: sterile alpha motif domain-containing protein 5 [Odobenus rosmarus divergens]
ENSG00000203730(TEDDM1)	--	0.0273622	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Family of unknown function (DUF716)	Transmembrane epididymal protein 1 GN=TEDDM1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane epididymal protein 1 [Loxodonta africana]
ENSG00000203734(ECT2L)	--	0.0385505	3	0.051332681	4	0.01280223	0	0.06386495	5	0.04996051	3	0.050906239	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; F-box domain;; F-box-like	Epithelial cell-transforming sequence 2 oncogene-like GN=ECT2L OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: epithelial cell-transforming sequence 2 oncogene-like isoform X3 [Galeopterus variegatus]
ENSG00000203737(GPR52)	--	0.172754	2	0	0	0	0	0.257057	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K08407|0|nle:100606395|GPR52; G protein-coupled receptor 52; K08407 G protein-coupled receptor 52 (A)	--	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family)	Probable G-protein coupled receptor 52 GN=GPR52 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 52-like [Tupaia chinensis]
ENSG00000203760(CENPW)	--	21.04683011	188	20.61360916	178	19.10560135	167	24.50883262	228	19.124145	178	23.37230618	218	0.935481361	0.245643802	normal	0.965822414	-0.021246054	normal	0.86052075	0.373222228	normal	0.581064194	0.205821985	normal	--	--	Biological Process: mitotic cell cycle (GO:0000278);; Molecular Function: DNA binding (GO:0003677);; Biological Process: kinetochore assembly (GO:0051382);; 	--	--	--	--	Centromere kinetochore component W	Centromere protein W GN=CENPW OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein W-like isoform X2 [Tupaia chinensis]
ENSG00000203772(SPRN)	--	2.56411	167	3.77465	247	3.37528	224	2.6457	171	2.5596	166	3.49777	230	0.967389858	0.003286083	normal	0.355865984	-0.590314903	normal	0.966686857	0.029646162	normal	0.643850771	-0.19046542	normal	--	--	Cellular Component: anchored component of membrane (GO:0031225);; 	--	--	--	--	"Shadow of prion protein, neuroprotective"	Shadow of prion protein (Precursor) GN=SPRN OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	--
ENSG00000203778(FAM229B)	--	6.620590275	89	5.605740285	72	8.99405361	91	6.202480508	77	9.94233032	106	7.491900229	84	0.96078915	-0.235405347	normal	0.821635124	0.52738875	normal	0.969156601	-0.121663612	normal	0.936570284	0.062880513	normal	--	--	--	--	--	--	--	UPF0731 family	Protein FAM229B GN=FAM229B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM229B isoformX1 [Canis lupus familiaris] 
ENSG00000203780(FANK1)	--	1.33444694	25	1.3118795	29	1.5231751	36	2.017547751	39	2.61205507	53	2.807295211	59	0.952904559	0.581888576	normal	0.774429237	0.816592753	normal	0.850839464	0.681844169	normal	0.19735921	0.727129187	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Fibronectin type 3 and ankyrin repeat domains protein 1 GN=FANK1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: fibronectin type 3 and ankyrin repeat domains protein 1 [Tupaia chinensis]
ENSG00000203797(DDO)	--	0.0264927	1	0.029263153	1	0	0	0.1953002	7	0.154779642	5	0.078902357	3	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00272|0|hsa:8528|DDO, DASOX, DDO-1, DDO-2; D-aspartate oxidase (EC:1.4.3.1); K00272 D-aspartate oxidase [EC:1.4.3.1] (A)"	"Alanine, aspartate and glutamate metabolism (ko00250);; Peroxisome (ko04146)"	[E]	Amino acid transport and metabolism	FAD dependent oxidoreductase	D-aspartate oxidase GN=DDO OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: D-aspartate oxidase [Equus caballus]
ENSG00000203805(PLPP4)	--	0	0	0.189102027	2	0.093009844	0	0.134357045	3	0.283494466	3	0.4100506	7	--	--	--	--	--	--	--	--	--	--	--	--	[I]	Lipid transport and metabolism	--	--	--	[I]	Lipid transport and metabolism	PAP2 superfamily	Phosphatidate phosphatase PPAPDC1A GN=PPAPDC1A OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: phosphatidate phosphatase PPAPDC1A [Tupaia chinensis]
ENSG00000203837(PNLIPRP3)	--	0	0	0	0	0	0	0	0	0	0	0.0833769	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K14076|0|hsa:119548|PNLIPRP3; pancreatic lipase-related protein 3 (EC:3.1.1.3); K14076 pancreatic lipase-related protein 3 [EC:3.1.1.3] (A)	Glycerolipid metabolism (ko00561)	--	--	Lipase;; PLAT/LH2 domain	Pancreatic lipase-related protein 3 (Precursor) GN=PNLIPRP3 OS=Homo sapiens (Human) PE=2 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: pancreatic lipase-related protein 3 [Galeopterus variegatus]
ENSG00000203867(RBM20)	--	2.25599561	306	1.468128359	222	1.927482299	261	1.806082114	259	2.159928401	317	2.199512304	309	0.918943699	-0.269936498	normal	0.579971202	0.489691673	normal	0.935215014	0.234018037	normal	0.67040182	0.145087656	normal	--	--	--	--	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; Zinc-finger double-stranded RNA-binding"	RNA-binding protein 20 GN=RBM20 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: RNA-binding protein 20 [Galeopterus variegatus]
ENSG00000203877(RIPPLY2)	--	2.046041	11	2.303590336	12	1.860350012	9	0.371366	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transcription Regulator	Protein ripply2 GN=RIPPLY2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein ripply2 [Loxodonta africana]
ENSG00000203879(GDI1)	--	57.40064292	2877	44.43410091	2245	54.1770714	2741	46.88543445	2356	43.48549078	2174	42.28760446	2151	0.921128701	-0.318869389	normal	0.986288727	-0.067743686	normal	0.86882747	-0.357762855	normal	0.13174031	-0.256325906	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: GDP-dissociation inhibitor activity (GO:0005092);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17255|0|ptr:450155|GDI1; GDP dissociation inhibitor 1; K17255 Rab GDP dissociation inhibitor (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	GDP dissociation inhibitor	Rab GDP dissociation inhibitor alpha GN=GDI1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: rab GDP dissociation inhibitor alpha [Galeopterus variegatus]
ENSG00000203880(PCMTD2)	--	10.3573615	770	9.196602359	739	9.662262434	741	8.764152638	687	8.627020716	712	10.10516311	814	0.954288089	-0.194968443	normal	0.972861557	-0.074967373	normal	0.969280715	0.127016403	normal	0.883616512	-0.044629666	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);; SOCS box	Protein-L-isoaspartate O-methyltransferase domain-containing protein 2 GN=PCMTD2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein-L-isoaspartate O-methyltransferase domain-containing protein 2 isoform 1 [Ceratotherium simum simum]
ENSG00000203883(SOX18)	--	3.24162	75	1.78296	42	2.13501	52	1.99275	47	1.31104	31	0.546206	13	0.755790894	-0.687112915	normal	0.962450848	-0.440993714	normal	0.001846934	-1.890337508	down	0.168492753	-0.917765406	normal	--	--	--	"K09270|2.0799e-145|hsa:54345|SOX18, HLTS; SRY (sex determining region Y)-box 18; K09270 transcription factor SOX7/8/10/18 (SOX group E/F) (A)"	--	[K]	Transcription	Sox C-terminal transactivation domain;; HMG (high mobility group) box;; HMG-box domain	Transcription factor SOX-18 GN=SOX18 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor SOX-18 [Chrysochloris asiatica]
ENSG00000203908(KHDC3L)	--	0	0	0	0	0.110912	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	KHDC3-like protein GN=KHDC3L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: KHDC3-like protein [Bubalus bubalis]
ENSG00000203910(C1orf146)	--	0	0	0	0	0	0	0.098552	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4580)	Uncharacterized protein C1orf146 GN=C1orf146 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf146 homolog [Ceratotherium simum simum]
ENSG00000203923(SPANXN1)	--	0	0	0.0391949	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Sperm protein associated with nucleus, mapped to X chromosome"	Sperm protein associated with the nucleus on the X chromosome N1 GN=SPANXN1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000203942(C10orf62)	--	0.1244	3	0	0	0	0	0.16574	4	0.040505	0	0.0409599	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C10orf62 GN=C10orf62 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C10orf62 homolog [Galeopterus variegatus]
ENSG00000203943(SAMD13)	--	0.497472955	10	0.631861229	11	0.433498081	8	0.911569229	17	0.891624007	18	0.791136882	18	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: sequence-specific DNA binding (GO:0043565);; 	--	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif);; Sterile alpha motif (SAM)/Pointed domain	Sterile alpha motif domain-containing protein 13 GN=SAMD13 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	hypothetical protein PANDA_016570 [Ailuropoda melanoleuca]
ENSG00000203950(FAM127B)	--	38.931	714	39.1558	721	41.5256	781	42.6404	789	41.1243	753	48.3771	901	0.970418552	0.113037517	normal	0.974745981	0.041139611	normal	0.956067524	0.197556684	normal	0.622401689	0.120027248	normal	--	--	--	--	--	--	--	--	Protein FAM127B GN=FAM127B OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein FAM127A-like [Galeopterus variegatus]
ENSG00000203952(CCDC160)	--	0.085012835	2	0.119062851	4	0.029681806	0	0	0	0.041065489	0	0.083109393	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 160 GN=CCDC160 OS=Homo sapiens (Human) PE=3 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 160 [Ursus maritimus]
ENSG00000203965(EFCAB7)	--	2.822780052	120	3.132179972	132	3.295780004	137	2.348064	101	3.163938	134	1.922234	82	0.945096716	-0.275658523	normal	0.967247498	0.000265494	normal	0.282233701	-0.738124676	normal	0.462339015	-0.316688764	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain pair;; EF hand;; Cytoskeletal-regulatory complex EF hand	EF-hand calcium-binding domain-containing protein 7 GN=EFCAB7 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: EF-hand calcium-binding domain-containing protein 7 [Galeopterus variegatus]
ENSG00000203985(LDLRAD1)	--	0	0	0	0	0	0	0.093342975	4	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Low-density lipoprotein receptor domain class A	Low-density lipoprotein receptor class A domain-containing protein 1 GN=LDLRAD1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: low-density lipoprotein receptor class A domain-containing protein 1 [Galeopterus variegatus]
ENSG00000203995(ZYG11A)	--	2.692831	195	1.687599541	122	2.21236546	160	2.072503918	163	2.3510652	180	1.658558305	115	0.923445795	-0.286957434	normal	0.645773951	0.534206505	normal	0.779739426	-0.479360627	normal	0.895946735	-0.080540252	normal	--	--	--	"K10350|0|hsa:440590|ZYG11A, ZYG11; zyg-11 family member A, cell cycle regulator; K10350 Zyg-11 protein homolog (A)"	--	[R]	General function prediction only	--	Protein zyg-11 homolog A GN=ZYG11A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein zyg-11 homolog A [Felis catus]
ENSG00000204052(LRRC73)	--	0.57736	20	0.650778	23	0.516714	18	1.1177	39	0.610346	21	0.33861	12	0.858421957	0.883290487	normal	0.986533091	-0.142838428	normal	--	--	--	0.86011184	0.214129006	normal	--	--	--	--	--	--	--	Leucine Rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 73 GN=LRRC73 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 73 isoform X1 [Oryctolagus cuniculus]
ENSG00000204060(FOXO6)	--	1.03860283	40	0.710511	26	1.307073	44	0.610182	21	0.633973	23	0.42961762	17	0.821825046	-0.91132807	normal	0.984734358	-0.186747725	normal	0.264983137	-1.305587927	normal	0.156423173	-0.871693058	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K17847|1.6255e-117|hgl:101718574|Foxo6; forkhead box O6; K17847 forkhead box protein O6 (A)	FoxO signaling pathway (ko04068)	[K]	Transcription	Fork head domain	Forkhead box protein O6 GN=FOXO6 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein O6 [Bison bison bison]
ENSG00000204070(SYS1)	--	17.39659682	544	18.52511536	576	20.6054526	534	21.774024	667	17.94335471	609	18.85245017	587	0.921458047	0.262577196	normal	0.971379747	0.058796722	normal	0.965003851	0.127883777	normal	0.545373684	0.149979186	normal	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Integral membrane protein S linking to the trans Golgi network	Protein SYS1 homolog GN=SYS1 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein SYS1 homolog isoform 1 [Dasypus novemcinctus] 
ENSG00000204084(INPP5B)	--	3.059878044	224	3.72428596	254	3.612057358	282	3.23458794	226	2.885540388	196	4.957786467	306	0.966867767	-0.017886088	normal	0.820575187	-0.392731384	normal	0.962398928	0.108983854	normal	0.860646009	-0.082103111	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	"K01099|0|ptr:456767|INPP5B; inositol polyphosphate-5-phosphatase, 75kDa; K01099 phosphatidylinositol-bisphosphatase [EC:3.1.3.36] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Endonuclease/Exonuclease/phosphatase family;; RhoGAP domain	"Type II inositol 1,4,5-trisphosphate 5-phosphatase (Precursor) GN=INPP5B OS=Homo sapiens (Human) PE=1 SV=4"	T	Signal transduction mechanisms	"PREDICTED: LOW QUALITY PROTEIN: type II inositol 1,4,5-trisphosphate 5-phosphatase [Loxodonta africana]"
ENSG00000204086(RPA4)	--	0	0	0.0368463	1	0.11023	2	0.0370394	1	0.18166	4	0.148916	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10741|5.31073e-155|hsa:29935|RPA4, HSU24186; replication protein A4, 30kDa; K10741 replication factor A4 (A)"	DNA replication (ko03030);; Nucleotide excision repair (ko03420);; Mismatch repair (ko03430);; Homologous recombination (ko03440);; Fanconi anemia pathway (ko03460)	[L]	"Replication, recombination and repair"	Replication protein A C terminal;; OB-fold nucleic acid binding domain	Replication protein A 30 kDa subunit GN=RPA4 OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: replication protein A 30 kDa subunit [Ceratotherium simum simum]
ENSG00000204099(NEU4)	--	0.409882304	14	0.614789526	27	0.57117339	27	0.17320813	4	0.226625831	6	0.62229982	24	--	--	--	0.150392134	-1.942962429	normal	0.985362064	-0.168217336	normal	0.331599244	-1.015759691	normal	--	--	--	K12357|0|hsa:129807|NEU4; sialidase 4 (EC:3.2.1.18); K12357 sialidase-2/3/4 [EC:3.2.1.18] (A)	Other glycan degradation (ko00511);; Sphingolipid metabolism (ko00600)	--	--	BNR repeat-like domain	Sialidase-4 GN=NEU4 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: sialidase-4 [Galeopterus variegatus]
ENSG00000204103(MAFB)	--	0	0	0	0	0	0	0.0703444	4	0.0170383	0	0.0696757	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09036|1.83755e-163|pon:100449843|MAFB; v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B; K09036 transcription factor MAFB (A)	--	[K]	Transcription	bZIP Maf transcription factor;; Maf N-terminal region	Transcription factor MafB GN=MAFB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor MafB [Orcinus orca] 
ENSG00000204104(TRAF3IP1)	--	6.820833	617	7.49699	688	8.199385	743	5.7765066	526	6.2387516	561	5.39974	487	0.922185324	-0.260336895	normal	0.878518336	-0.315065909	normal	0.064632906	-0.616170995	normal	0.031181675	-0.400924749	normal	--	--	--	--	--	[Z]	Cytoskeleton	Microtubule-binding protein MIP-T3	TRAF3-interacting protein 1 GN=TRAF3IP1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: TRAF3-interacting protein 1 [Galeopterus variegatus]
ENSG00000204116(CHIC1)	--	5.033552	444	6.4985241	591	6.399664	548	6.505448	597	6.79735203	620	7.3663122	670	0.740283614	0.395156089	normal	0.972164966	0.047564694	normal	0.909005131	0.28099136	normal	0.289076977	0.232637464	normal	--	--	--	--	--	[R]	General function prediction only	Golgin subfamily A member 7/ERF4 family	Cysteine-rich hydrophobic domain-containing protein 1 GN=CHIC1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: cysteine-rich hydrophobic domain 1 protein isoform 3 [Trichechus manatus latirostris] 
ENSG00000204118(NAP1L6)	--	0.167353	7	0.306627	13	0.350573	14	0.0236554	1	0	0	0.0236317	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Nucleosome assembly protein (NAP)	Putative nucleosome assembly protein 1-like 6 GN=NAP1L6 OS=Homo sapiens (Human) PE=5 SV=1	B	Chromatin structure and dynamics	PREDICTED: nucleosome assembly protein 1-like 2-like [Vicugna pacos]
ENSG00000204128(C2orf72)	--	4.306249	258	4.286753	263	3.521834	215	2.390755616	144	1.828044649	109	1.665689529	100	0.006777886	-0.865134774	normal	1.57E-06	-1.280346647	down	0.000244258	-1.100995252	down	2.24E-05	-1.082756355	down	--	--	--	--	--	--	--	Domain of unknown function (DUF4630)	Uncharacterized protein C2orf72 GN=C2orf72 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C2orf72 homolog isoform X3 [Mustela putorius furo]
ENSG00000204130(RUFY2)	--	7.722411493	540	5.443561	373	6.857984661	477	6.0956494	434	6.238725	448	5.272979009	340	0.838433392	-0.344999108	normal	0.929836566	0.242000242	normal	0.453757235	-0.494878465	normal	0.53154345	-0.207501055	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[T]	Signal transduction mechanisms	RUN domain;; FYVE zinc finger	RUN and FYVE domain-containing protein 2 GN=RUFY2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: RUN and FYVE domain-containing protein 2 isoform X1 [Ailuropoda melanoleuca] 
ENSG00000204131(NHSL2)	--	0.504596212	106	0.518277375	90	0.467170306	82	0.213502	46	0.351918615	72	0.241496806	51	0.004837018	-1.207832985	down	0.94111573	-0.33700918	normal	0.729365992	-0.67743041	normal	0.079245791	-0.739040196	normal	--	--	--	--	--	--	--	NHS-like	NHS-like protein 2 GN=NHSL2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: NHS-like protein 2 [Ceratotherium simum simum]
ENSG00000204138(PHACTR4)	--	8.438207	913	9.113813	950	8.93745599	882	8.490774235	928	10.27833297	1114	11.69423815	1096	0.97856489	-0.007310117	normal	0.956395736	0.208017205	normal	0.897385274	0.304636354	normal	0.402102147	0.172288522	normal	--	--	--	"K17585|0|hsa:65979|PHACTR4, PPP1R124; phosphatase and actin regulator 4; K17585 phosphatase and actin regulator 4 (A)"	--	[R]	General function prediction only	RPEL repeat	Phosphatase and actin regulator 4 GN=PHACTR4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: phosphatase and actin regulator 4 isoform X4 [Physeter catodon]
ENSG00000204147(ASAH2B)	--	2.396451712	120	2.432611209	125	2.751571922	111	2.927380941	127	3.391835945	155	3.229989772	155	0.968496029	0.050335351	normal	0.931420364	0.285803425	normal	0.803962793	0.467997693	normal	0.51567718	0.275024233	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Neutral/alkaline non-lysosomal ceramidase	Putative inactive neutral ceramidase B GN=ASAH2B OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neutral ceramidase [Panthera tigris altaica]
ENSG00000204149(AGAP6)	--	10.39043938	816	10.87965	841	12.34187	880	11.723793	889	12.31264349	1001	11.769816	950	0.974068543	0.092614909	normal	0.946407631	0.229459119	normal	0.974267105	0.101963866	normal	0.525354001	0.141925341	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; PH domain;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Pleckstrin homology domain;; Ankyrin repeats (many copies);; Ankyrin repeat	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 5 GN=AGAP5 OS=Homo sapiens (Human) PE=2 SV=2"	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 isoform X5 [Mustela putorius furo]"
ENSG00000204160(ZDHHC18)	--	8.905611235	563	9.297240965	558	11.02606882	620	10.69681159	759	10.07490352	692	9.161198155	583	0.720961925	0.399191476	normal	0.903962053	0.288377388	normal	0.969484543	-0.096820189	normal	0.359775626	0.202626242	normal	[R]	General function prediction only	--	"K16675|0|hsa:84243|ZDHHC18, DHHC-18, DHHC18; zinc finger, DHHC-type containing 18 (EC:2.3.1.225); K16675 palmitoyltransferase ZDHHC9/14/18 [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Palmitoyltransferase ZDHHC18 GN=ZDHHC18 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: palmitoyltransferase ZDHHC18 [Galeopterus variegatus]
ENSG00000204172(AGAP9)	--	4.541962	680	4.478534	689	5.723652	762	6.075365	971	7.396818	1069	7.558162	1091	0.413984293	0.482188331	normal	0.063347057	0.6111744	normal	0.303365658	0.508648733	normal	0.00067423	0.534470349	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	Putative GTPase activating protein for Arf;; PH domain;; Pleckstrin homology domain	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 10 GN=AGAP10 OS=Homo sapiens (Human) PE=2 SV=3"	U	"Intracellular trafficking, secretion, and vesicular transport"	"PREDICTED: arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 [Bos mutus]"
ENSG00000204174(NPY4R)	--	0.9931252	31	0.980882	30	0.966897	27	6.0676	185	6.28772	194	5.75406	180	7.77E-16	2.489350582	up	0	2.612443312	up	0	2.662374476	up	1.01E-16	2.645830647	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04206|0|hsa:5540|NPY4R, NPY4-R, PP1, PPYR1, Y4; neuropeptide Y receptor Y4; K04206 neuropeptide Y receptor type 4 (A)"	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuropeptide Y receptor type 4 GN=NPY4R OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuropeptide Y receptor type 4 [Orcinus orca] 
ENSG00000204175(GPRIN2)	--	24.25150802	1448	25.85873885	1550	25.08360664	1524	11.87312875	638	11.5888073	590	10.98487512	613	2.17E-10	-1.21127197	down	6.87E-14	-1.412583802	down	2.02E-12	-1.320057165	down	1.68E-21	-1.317793733	down	--	--	--	--	--	--	--	G protein-regulated inducer of neurite outgrowth C-terminus	G protein-regulated inducer of neurite outgrowth 2 GN=GPRIN2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	G protein-regulated inducer of neurite outgrowth 2 [Sus scrofa] 
ENSG00000204176(SYT15)	--	2.452218164	151	3.909174699	161	2.759499556	143	0.975232218	63	0.949689036	44	0.655996987	43	0.000147043	-1.271277529	down	2.52E-09	-1.857191668	down	1.84E-07	-1.707023809	down	5.10E-07	-1.623568231	down	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-15 GN=SYT15 OS=Homo sapiens (Human) PE=2 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-15 [Galeopterus variegatus]
ENSG00000204178(TMEM57)	--	3.685388562	283	3.560650804	272	2.912481259	221	5.399549013	419	5.804559	447	4.304740068	334	0.354387568	0.532924628	normal	0.037358834	0.692210657	normal	0.260055986	0.584236015	normal	0.004507365	0.606777665	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Transmembrane protein	Macoilin GN=TMEM57 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: macoilin isoform X1 [Elephantulus edwardii]
ENSG00000204179(PTPN20)	--	5.570766473	126	5.916818122	157	7.921259501	172	5.845067278	165	5.082592175	139	5.125994723	153	0.899595084	0.354423951	normal	0.952428695	-0.195107428	normal	0.955814986	-0.175530993	normal	0.985893701	-0.014845999	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; 	"K18039|0|hsa:26095|PTPN20B, CT126, PTPN20A, bA142I17.1, bA42B19.1, hPTPN20, PTPN20; protein tyrosine phosphatase, non-receptor type 20B (EC:3.1.3.48); K18039 tyrosine-protein phosphatase non-receptor type 20 [EC:3.1.3.48] (A)"	--	[T]	Signal transduction mechanisms	Protein-tyrosine phosphatase	Tyrosine-protein phosphatase non-receptor type 20 GN=PTPN20B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein phosphatase non-receptor type 20 [Galeopterus variegatus]
ENSG00000204186(ZDBF2)	--	5.726439504	998	6.073896755	1038	6.110174855	1025	1.702355181	303	1.692676076	293	1.914268966	334	0	-1.745374958	down	0	-1.840863033	down	0	-1.621580033	down	6.10E-30	-1.739616354	down	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	DBF zinc finger	DBF4-type zinc finger-containing protein 2 GN=ZDBF2 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: DBF4-type zinc finger-containing protein 2 [Galeopterus variegatus]
ENSG00000204209(DAXX)	--	15.16916197	916	14.57497477	890	16.20127835	954	16.60599129	981	16.4995219	966	14.38907443	866	0.977118949	0.067963112	normal	0.974382608	0.096633661	normal	0.968474888	-0.147667887	normal	0.987212077	0.00600963	normal	--	--	--	"K02308|0|hsa:1616|DAXX, BING2, DAP6, EAP1; death-domain associated protein; K02308 death-associated protein 6 (A)"	MAPK signaling pathway (ko04010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Herpes simplex infection (ko05168)	--	--	Daxx Family	Death domain-associated protein 6 GN=DAXX OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: death domain-associated protein 6 [Galeopterus variegatus] 
ENSG00000204217(BMPR2)	--	9.607207311	1749	11.06848457	1926	9.298126727	1746	10.20417288	1934	11.2880612	2120	8.373116109	1554	0.98208529	0.114129876	normal	0.982664815	0.116942461	normal	0.972929212	-0.176196632	normal	0.932686461	0.027110483	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: transmembrane receptor protein serine/threonine kinase activity (GO:0004675);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; Cellular Component: membrane (GO:0016020);; 	"K04671|0|hsa:659|BMPR2, BMPR-II, BMPR3, BMR2, BRK-3, POVD1, PPH1, T-ALK; bone morphogenetic protein receptor, type II (serine/threonine kinase) (EC:2.7.11.30); K04671 bone morphogenetic protein receptor type-2 [EC:2.7.11.30] (A)"	Cytokine-cytokine receptor interaction (ko04060);; TGF-beta signaling pathway (ko04350);; Hippo signaling pathway (ko04390);; Signaling pathways regulating pluripotency of stem cells (ko04550);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Activin types I and II receptor domain	Bone morphogenetic protein receptor type-2 (Precursor) GN=BMPR2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: bone morphogenetic protein receptor type-2 [Pteropus alecto] 
ENSG00000204219(TCEA3)	--	0.677756443	27	0.786994975	22	0.33366723	15	0.236391539	11	0.145923105	5	0.291929966	11	0.807502939	-1.214788979	normal	0.424517732	-1.87042986	normal	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: nucleus (GO:0005634);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: zinc ion binding (GO:0008270);; "	--	--	[K]	Transcription	"Transcription factor S-II (TFIIS), central domain;; Transcription factor S-II (TFIIS);; TFIIS helical bundle-like domain"	Transcription elongation factor A protein 3 GN=TCEA3 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: transcription elongation factor A protein 3 isoform 2 [Ceratotherium simum simum]
ENSG00000204220(PFDN6)	--	83.70217501	669	87.985208	716	94.6134447	761	81.79923794	676	81.50210337	624	67.01156898	559	0.974831614	-0.015779178	normal	0.944564991	-0.21934339	normal	0.54771434	-0.45228662	normal	0.275337731	-0.228722094	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein folding (GO:0006457);; Cellular Component: prefoldin complex (GO:0016272);; Molecular Function: unfolded protein binding (GO:0051082);; 	K04798|3.91144e-75|ptg:102950418|PFDN6; prefoldin subunit 6; K04798 prefoldin beta subunit (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Prefoldin subunit	Prefoldin subunit 6 GN=PFDN6 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	prefoldin subunit 6 [Canis lupus familiaris] 
ENSG00000204227(RING1)	--	12.2576	454	10.1326	394	11.6159	451	9.91101	373	11.3363	414	12.1916	454	0.880200346	-0.313177376	normal	0.967876063	0.049822021	normal	0.970877211	0.00126918	normal	0.788536404	-0.086343422	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	K10695|0|nle:100579291|RING1; ring finger protein 1; K10695 E3 ubiquitin-protein ligase RNF1/2 [EC:6.3.2.19] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc-finger of the MIZ type in Nse subunit"	E3 ubiquitin-protein ligase RING1 GN=RING1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RING1 isoform X1 [Equus przewalskii]
ENSG00000204228(HSD17B8)	--	13.88273	219	10.66656	173	14.28644	228	7.926166	128	7.77975	122	6.993008	109	0.03658675	-0.798200894	normal	0.684131062	-0.51987659	normal	0.000350225	-1.062571994	down	0.003951175	-0.809615746	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	K13370|0|ptr:746685|HSD17B8; hydroxysteroid (17-beta) dehydrogenase 8; K13370 17beta-estradiol 17-dehydrogenase / 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) [EC:1.1.1.62 1.1.1.239] (A)	Steroid hormone biosynthesis (ko00140)	[I]	Lipid transport and metabolism	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain	Estradiol 17-beta-dehydrogenase 8 GN=HSD17B8 OS=Homo sapiens (Human) PE=1 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: estradiol 17-beta-dehydrogenase 8 [Equus caballus]
ENSG00000204231(RXRB)	--	8.47409	473	8.00035	455	8.18959	464	9.71553	540	9.48517	523	11.4306	640	0.95823265	0.159800916	normal	0.952969041	0.178962697	normal	0.555939918	0.454389448	normal	0.217303256	0.270222236	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08525|0|tup:102495243|RXRB; retinoid X receptor, beta; K08525 retinoid X receptor beta (A)"	PPAR signaling pathway (ko03320);; Thyroid hormone signaling pathway (ko04919);; Adipocytokine signaling pathway (ko04920);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Thyroid cancer (ko05216);; Small cell lung cancer (ko05222);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Retinoic acid receptor RXR-beta GN=RXRB OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: retinoic acid receptor RXR-beta isoform X1 [Physeter catodon]
ENSG00000204237(OXLD1)	--	35.99956	267	36.29952	280	40.9205	322	33.03844	258	31.17967	234	29.91651	229	0.964573656	-0.079833552	normal	0.915269488	-0.278695775	normal	0.542787708	-0.497221716	normal	0.307471799	-0.290639658	normal	--	--	--	--	--	--	--	"Oxidoreductase-like protein, N-terminal"	Oxidoreductase-like domain-containing protein 1 GN=OXLD1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: oxidoreductase-like domain-containing protein 1 [Equus przewalskii]
ENSG00000204248(COL11A2)	--	0.345076984	43	0.210706828	34	0.238911509	38	0.332622248	16	0.259723266	40	0.248251811	41	0.205118814	-1.37357867	normal	0.978332471	0.204640078	normal	0.980959274	0.097593222	normal	0.73984257	-0.264198538	normal	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; 	"K06236|0|pps:100992124|COL11A2; collagen, type XI, alpha 2; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; Laminin G domain;; Concanavalin A-like lectin/glucanases superfamily	Collagen alpha-2(XI) chain (Precursor) GN=COL11A2 OS=Homo sapiens (Human) PE=1 SV=5	W	Extracellular structures	PREDICTED: collagen alpha-2(XI) chain isoform 1 [Ceratotherium simum simum]
ENSG00000204252(HLA-DOA)	--	0	0	0	0	0	0	0	0	0	0	0.030786873	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; Biological Process: antigen processing and presentation (GO:0019882);; Cellular Component: MHC class II protein complex (GO:0042613);; 	"K06752|0|hsa:3111|HLA-DOA, HLA-DNA, HLA-DZA, HLADZ; major histocompatibility complex, class II, DO alpha; K06752 major histocompatibility complex, class II (A)"	Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Intestinal immune network for IgA production (ko04672);; Type I diabetes mellitus (ko04940);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Asthma (ko05310);; Autoimmune thyroid disease (ko05320);; Inflammatory bowel disease (IBD) (ko05321);; Systemic lupus erythematosus (ko05322);; Rheumatoid arthritis (ko05323);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	"Class II histocompatibility antigen, alpha domain;; Immunoglobulin C1-set domain;; CD80-like C2-set immunoglobulin domain"	"HLA class II histocompatibility antigen, DO alpha chain (Precursor) GN=HLA-DOA OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: HLA class II histocompatibility antigen, DO alpha chain-like [Ceratotherium simum simum]"
ENSG00000204256(BRD2)	--	40.246997	2797	42.61773914	3033	35.90676	2466	36.90736	2618	37.048863	2696	41.6886265	3010	0.985496336	-0.126175759	normal	0.978806734	-0.191250344	normal	0.951116027	0.279144057	normal	0.959389613	-0.016221497	normal	[BK]	Chromatin structure and dynamics;; Transcription	Molecular Function: protein binding (GO:0005515);; 	K08871|0|lve:103085719|BRD2; bromodomain containing 2; K08871 bromodomain-containing protein 2 (A)	--	[K]	Transcription	Bromodomain;; Putative binding domain	Bromodomain-containing protein 2 GN=BRD2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: bromodomain-containing protein 2 isoform X1 [Orycteropus afer afer]
ENSG00000204257(HLA-DMA)	--	3.1906842	53	3.74375	62	4.0147517	65	6.696352021	119	9.5564665	176	9.815719726	180	0.008916901	1.11397495	up	1.88E-06	1.461731036	up	1.78E-06	1.440211768	up	1.43E-05	1.3801982	up	--	--	Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; Biological Process: antigen processing and presentation (GO:0019882);; Cellular Component: MHC class II protein complex (GO:0042613);; 	"K06752|0|pps:100968989|HLA class II histocompatibility antigen, DM alpha chain; K06752 major histocompatibility complex, class II (A)"	Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Intestinal immune network for IgA production (ko04672);; Type I diabetes mellitus (ko04940);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Asthma (ko05310);; Autoimmune thyroid disease (ko05320);; Inflammatory bowel disease (IBD) (ko05321);; Systemic lupus erythematosus (ko05322);; Rheumatoid arthritis (ko05323);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	"Class II histocompatibility antigen, alpha domain;; Immunoglobulin C1-set domain"	"HLA class II histocompatibility antigen, DM alpha chain (Precursor) GN=HLA-DMA OS=Homo sapiens (Human) PE=1 SV=1"	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: HLA class II histocompatibility antigen, DM alpha chain [Orycteropus afer afer]"
ENSG00000204262(COL5A2)	--	43.62511523	6753	38.35001911	6070	40.7568842	6354	53.49561709	8266	55.069019	8410	45.93111877	7063	0.980396956	0.260774844	normal	0.763578475	0.448887333	normal	0.991942561	0.144291978	normal	0.108149278	0.286286178	normal	--	--	Molecular Function: extracellular matrix structural constituent (GO:0005201);; Molecular Function: protein binding (GO:0005515);; 	"K06236|0|ptr:459817|COL5A2; collagen, type V, alpha 2; K06236 collagen, type I/II/III/V/XI/XXIV/XXVII, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Protein digestion and absorption (ko04974);; Amoebiasis (ko05146)	[W]	Extracellular structures	Collagen triple helix repeat (20 copies);; Fibrillar collagen C-terminal domain;; von Willebrand factor type C domain	Collagen alpha-2(V) chain (Precursor) GN=COL5A2 OS=Homo sapiens (Human) PE=1 SV=3	W	Extracellular structures	PREDICTED: collagen alpha-2(V) chain [Tupaia chinensis]
ENSG00000204264(PSMB8)	--	13.61376	242	13.09675	242	10.30247	190	26.6665	480	25.69269	446	21.84968	382	9.54E-05	0.952821388	normal	0.001426129	0.856608895	normal	9.47E-05	0.993593481	normal	3.00E-06	0.934273497	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02740|0|pps:100969919|PSMB8; proteasome (prosome, macropain) subunit, beta type, 8; K02740 20S proteasome subunit beta 8 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-8 (Precursor) GN=PSMB8 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-8 [Ceratotherium simum simum]
ENSG00000204267(TAP2)	--	10.0433728	771	10.046101	794	9.722981229	771	13.999539	1051	14.556775	1073	11.4184527	847	0.669671129	0.415416171	normal	0.693232963	0.412334746	normal	0.969811661	0.127101734	normal	0.06293818	0.325123926	normal	[V]	Defense mechanisms	"Molecular Function: ATP binding (GO:0005524);; Biological Process: transport (GO:0006810);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: ATPase activity (GO:0016887);; Molecular Function: ATPase activity, coupled to transmembrane movement of substances (GO:0042626);; Biological Process: transmembrane transport (GO:0055085);; "	"K05654|0|hsa:6891|TAP2, ABC18, ABCB3, APT2, D6S217E, PSF-2, PSF2, RING11; transporter 2, ATP-binding cassette, sub-family B (MDR/TAP); K05654 ATP-binding cassette, subfamily B (MDR/TAP), member 3 (A)"	ABC transporters (ko02010);; Phagosome (ko04145);; Antigen processing and presentation (ko04612);; Herpes simplex infection (ko05168);; Primary immunodeficiency (ko05340)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ABC transporter transmembrane region;; ABC transporter	Antigen peptide transporter 2 GN=TAP2 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: antigen peptide transporter 2 isoform X1 [Equus caballus] 
ENSG00000204271(SPIN3)	--	6.887007711	424	7.4537178	480	8.846664017	468	6.582239627	404	5.506453048	337	6.850341512	410	0.965230392	-0.100169315	normal	0.342293054	-0.529709459	normal	0.947405047	-0.198490259	normal	0.24334465	-0.274583328	normal	--	--	Biological Process: gamete generation (GO:0007276);; 	--	--	--	--	Spin/Ssty Family	Spindlin-3 GN=SPIN3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: spindlin-3 [Galeopterus variegatus]
ENSG00000204272(NBDY)	--	71.71405277	800	70.81270208	741	64.55490332	723	46.683933	590	59.58255701	652	62.47118506	732	0.476257894	-0.469063713	normal	0.950055857	-0.205580485	normal	0.975894827	0.009536734	normal	0.293801287	-0.218380322	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	"PREDICTED: uncharacterized protein LOC101401292, partial [Ceratotherium simum simum]"
ENSG00000204291(COL15A1)	--	0	0	0	0	0.09980902	2	0.292933047	25	0.520523748	49	0.427457795	37	0.00023007	4.095834758	up	1.29E-10	5.051474781	up	9.70E-06	3.448493027	up	4.17E-10	5.779842724	up	--	--	Molecular Function: structural molecule activity (GO:0005198);; Biological Process: cell adhesion (GO:0007155);; Cellular Component: extracellular matrix (GO:0031012);; 	"K08135|0|hsa:1306|COL15A1; collagen, type XV, alpha 1; K08135 collagen, type XV, alpha (A)"	Protein digestion and absorption (ko04974)	[W]	Extracellular structures	Collagenase NC10 and Endostatin;; Collagen triple helix repeat (20 copies);; Concanavalin A-like lectin/glucanases superfamily	Restin-4 (Precursor) GN=COL15A1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(XV) chain [Galeopterus variegatus]
ENSG00000204301(NOTCH4)	--	0.428443308	15	0.391233133	13	0.734877883	18	1.285234134	38	0.495129521	15	0.157033407	8	0.545742933	1.228732003	normal	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; Biological Process: Notch signaling pathway (GO:0007219);; Biological Process: multicellular organismal development (GO:0007275);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: cell differentiation (GO:0030154);; 	"K02599|0|hsa:4855|NOTCH4, INT3; notch 4; K02599 Notch (A)"	Dorso-ventral axis formation (ko04320);; Notch signaling pathway (ko04330);; Thyroid hormone signaling pathway (ko04919);; MicroRNAs in cancer (ko05206)	[T]	Signal transduction mechanisms	EGF-like domain;; Ankyrin repeat;; Calcium-binding EGF domain;; Ankyrin repeats (3 copies);; Human growth factor-like EGF;; Ankyrin repeats (many copies);; LNR domain;; Ankyrin repeats (many copies);; Ankyrin repeat;; NOTCH protein;; NOTCH protein	Notch 4 intracellular domain (Precursor) GN=NOTCH4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: neurogenic locus notch homolog protein 4 [Ceratotherium simum simum]
ENSG00000204304(PBX2)	--	12.6489	788	10.2692	654	11.2109	710	11.632	727	13.1894	815	10.6469	666	0.965821544	-0.146774465	normal	0.900490288	0.295469772	normal	0.970761214	-0.100367516	normal	0.967635723	0.015716168	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K15609|0|ptr:462585|PBX2, PBX2P1; pre-B-cell leukemia homeobox 2; K15609 pre-B-cell leukemia transcription factor 2 (A)"	--	[K]	Transcription	PBC domain;; Homeobox domain;; Homeobox KN domain	Pre-B-cell leukemia transcription factor 2 GN=PBX2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: pre-B-cell leukemia transcription factor 2 [Ovis aries]
ENSG00000204305(AGER)	--	0.898549131	16	0.950396028	29	0.524691737	16	0.492542389	15	1.142987084	27	0.716818322	15	--	--	--	0.984039404	-0.118133919	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	CD80-like C2-set immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Advanced glycosylation end product-specific receptor (Precursor) GN=AGER OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: advanced glycosylation end product-specific receptor [Galeopterus variegatus]
ENSG00000204308(RNF5)	--	27.5221	528	27.8957	552	30.6231	604	25.3903	496	28.1133	534	27.6027	534	0.96485422	-0.120667694	normal	0.969790299	-0.069062699	normal	0.953692726	-0.185505938	normal	0.63203599	-0.127400278	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K10666|1.89788e-98|ptr:745946|RNF5; ring finger protein 5, E3 ubiquitin protein ligase; K10666 E3 ubiquitin-protein ligase RNF5 [EC:6.3.2.19] (A)"	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; zinc-RING finger domain"	E3 ubiquitin-protein ligase RNF5 GN=RNF5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF5 isoform 2 [Ceratotherium simum simum]
ENSG00000204310(AGPAT1)	--	27.88145	1105	24.21901165	970	27.86528533	1122	30.14767203	1225	26.506266	1077	29.86743	1209	0.975853544	0.117747582	normal	0.972331161	0.129343605	normal	0.977645462	0.099321138	normal	0.613297155	0.114045872	normal	--	--	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	K13509|0|mcf:101865968|1-acyl-sn-glycerol-3-phosphate acyltransferase alpha; K13509 lysophosphatidate acyltransferase [EC:2.3.1.51] (A)	Glycerolipid metabolism (ko00561);; Glycerophospholipid metabolism (ko00564);; Fat digestion and absorption (ko04975)	[I]	Lipid transport and metabolism	Acyltransferase	1-acyl-sn-glycerol-3-phosphate acyltransferase alpha (Precursor) GN=AGPAT1 OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha isoform X1 [Eptesicus fuscus]
ENSG00000204311(DFNB59)	--	2.095885423	93	1.747939084	71	1.55118848	67	0.672684373	33	1.211775665	51	1.505297129	64	0.000456443	-1.482646145	down	0.913957216	-0.486465045	normal	0.974744265	-0.072701463	normal	0.158394777	-0.661824936	normal	--	--	--	--	--	--	--	Gasdermin family	Pejvakin GN=DFNB59 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pejvakin [Pteropus alecto]
ENSG00000204314(PRRT1)	--	1.136264919	24	1.354405	24	0.553668	14	0.611140135	16	0.336348	8	0.340664037	9	0.976987289	-0.570754908	normal	0.713329641	-1.442416972	normal	--	--	--	--	--	--	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced transmembrane protein	Proline-rich transmembrane protein 1 GN=PRRT1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: proline-rich transmembrane protein 1 [Chrysochloris asiatica]
ENSG00000204315(FKBPL)	--	4.906055206	112	4.449842704	102	4.956622272	114	5.249404	121	4.864057	111	5.282381	123	0.967998666	0.079625046	normal	0.966499947	0.099154485	normal	0.966662308	0.100054982	normal	0.878575455	0.0930778	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	FK506-binding protein-like GN=FKBPL OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: FK506-binding protein-like [Ursus maritimus]
ENSG00000204316(MRPL38)	--	43.4081	1167	38.473	1091	42.4924	1184	45.7864	1271	48.7293	1288	43.9062	1173	0.97868991	0.09221086	normal	0.956153733	0.217776849	normal	0.981318107	-0.021729625	normal	0.683169758	0.095402696	normal	--	--	--	"K17419|0|hsa:64978|MRPL38, L38MT, MRP-L3, MRP-L38, RPML3; mitochondrial ribosomal protein L38; K17419 large subunit ribosomal protein L38 (A)"	--	[R]	General function prediction only	Phosphatidylethanolamine-binding protein	"39S ribosomal protein L38, mitochondrial (Precursor) GN=MRPL38 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L38, mitochondrial [Mustela putorius furo] "
ENSG00000204323(SMIM5)	--	0.1696942	14	0.2409182	18	0.3177614	28	0.1889058	10	0.240728	16	0.639584	43	--	--	--	--	--	--	0.942447394	0.584949729	normal	--	--	--	--	--	--	--	--	--	--	--	Small integral membrane protein 5 GN=SMIM5 OS=Homo sapiens (Human) PE=4 SV=2	S	Function unknown	PREDICTED: small integral membrane protein 5 [Tupaia chinensis]
ENSG00000204335(SP5)	--	0.58893	18	0.190841	6	0.184048	5	0.0324802	1	0.156882	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09195|0|hsa:389058|SP5; Sp5 transcription factor; K09195 transcription factor Sp5 (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Transcription factor Sp5 GN=SP5 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor Sp5-like isoform X2 [Mustela putorius furo]
ENSG00000204344(STK19)	--	2.77538029	78	2.992932211	88	2.424688254	71	3.962779784	112	4.29925029	119	4.744628787	133	0.855763945	0.483141466	normal	0.895081032	0.407911478	normal	0.078336299	0.883282196	normal	0.121913631	0.598082838	normal	--	--	--	"K08880|0|hsa:8859|STK19, D6S60, D6S60E, G11, HLA-RP1, RP1; serine/threonine kinase 19 (EC:2.7.11.1); K08880 serine/threonine kinase 19 [EC:2.7.11.1] (A)"	--	--	--	Serine-threonine protein kinase 19	Serine/threonine-protein kinase 19 GN=STK19 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: serine/threonine-protein kinase 19 [Ceratotherium simum simum]
ENSG00000204348(DXO)	--	4.423265	131	3.2362757	97	3.976019	122	4.189093	103	3.924649	117	5.100996	156	0.906081636	-0.372810005	normal	0.950465257	0.245535662	normal	0.909305021	0.342608922	normal	0.891521482	0.083618991	normal	--	--	--	"K14845|0|hsa:1797|DXO, DOM3L, DOM3Z, NG6, RAI1; decapping exoribonuclease; K14845 RAT1-interacting protein (A)"	--	[L]	"Replication, recombination and repair"	RAI1 like PD-(D/E)XK nuclease	Decapping and exoribonuclease protein GN=DXO OS=Homo sapiens (Human) PE=2 SV=2	L	"Replication, recombination and repair"	PREDICTED: decapping and exoribonuclease protein [Equus caballus]
ENSG00000204351(SKIV2L)	--	14.92549	995	11.54802	856	14.8357	947	11.35001	764	12.41474464	837	12.64282	824	0.682102898	-0.411229046	normal	0.97595362	-0.053713762	normal	0.953509362	-0.208654011	normal	0.239652757	-0.227269992	normal	[L]	"Replication, recombination and repair"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K12599|0|hsa:6499|SKIV2L, 170A, DDX13, HLP, SKI2, SKI2W, SKIV2, THES2; superkiller viralicidic activity 2-like (S. cerevisiae); K12599 antiviral helicase SKI2 [EC:3.6.4.-] (A)"	RNA degradation (ko03018)	[A]	RNA processing and modification	DSHCT (NUC185) domain;; rRNA-processing arch domain;; DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	Helicase SKI2W GN=SKIV2L OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: helicase SKI2W isoform X1 [Camelus ferus]
ENSG00000204352(C9orf129)	--	0.163019	3	0.480502	9	0.310859	5	0.161285	3	0.156528	2	0.160059	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative uncharacterized protein C9orf129 GN=C9orf129 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: constitutive coactivator of PPAR-gamma-like protein 1-like [Sarcophilus harrisii]
ENSG00000204356(NELFE)	--	30.72781728	973	32.0423245	981	33.78737976	1036	29.44841147	925	29.471998	880	28.305045	857	0.974507874	-0.103650807	normal	0.962550425	-0.177886459	normal	0.91690409	-0.281495831	normal	0.349696621	-0.18895557	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K15182|0|mcf:102134460|NELFE; negative elongation factor complex member E; K15182 negative elongation factor E (A)	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain)"	Negative elongation factor E GN=NELFE OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: negative elongation factor E [Vicugna pacos]
ENSG00000204361(NXPE2)	--	0.134519	5	0.109296	4	0	0	0.0269916	1	0.262357	9	0.0266793	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Neurexophilin	NXPE family member 2 GN=NXPE2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: NXPE family member 2 [Ceratotherium simum simum]
ENSG00000204366(ZBTB12)	--	4.22597	150	3.83798	140	5.33354	196	3.83818	138	4.12077	146	5.48119	197	0.960699472	-0.149529012	normal	0.966359704	0.038705564	normal	0.967026044	-0.000942215	normal	0.955958996	-0.034470265	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10499|0|hsa:221527|ZBTB12, Bat9, C6orf46, D6S59E, G10, NG35; zinc finger and BTB domain containing 12; K10499 zinc finger and BTB domain-containing protein 12 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger of C2H2 type"	Zinc finger and BTB domain-containing protein 12 GN=ZBTB12 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger and BTB domain-containing protein 12 [Bison bison bison]
ENSG00000204370(SDHD)	--	54.261765	869	54.525068	884	60.365697	925	63.133955	1034	61.188928	941	57.093828	917	0.950792264	0.219619535	normal	0.976136719	0.068608028	normal	0.978503414	-0.020788938	normal	0.719693589	0.08943202	normal	--	--	--	"K00237|9.08176e-80|pps:100975025|SDHD; succinate dehydrogenase complex, subunit D, integral membrane protein; K00237 succinate dehydrogenase (ubiquinone) membrane anchor subunit (A)"	Citrate cycle (TCA cycle) (ko00020);; Oxidative phosphorylation (ko00190);; Carbon metabolism (ko01200);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[CU]	"Energy production and conversion;; Intracellular trafficking, secretion, and vesicular transport"	CybS	"Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial (Precursor) GN=SDHD OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: succinate dehydrogenase [ubiquinone] cytochrome b small subunit, mitochondrial isoform X1 [Vicugna pacos]"
ENSG00000204371(EHMT2)	--	12.22966376	1112	12.53257766	1167	12.50145551	1165	12.47676408	1144	11.769261	1063	13.261385	1209	0.9808938	0.010084264	normal	0.969818746	-0.155877775	normal	0.980851767	0.045135331	normal	0.908434478	-0.032807232	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: histone-lysine N-methyltransferase activity (GO:0018024);; Biological Process: histone lysine methylation (GO:0034968);; 	K11420|0|pon:100460372|EHMT2; euchromatic histone-lysine N-methyltransferase 2; K11420 euchromatic histone-lysine N-methyltransferase [EC:2.1.1.43] (A)	Lysine degradation (ko00310)	[BK]	Chromatin structure and dynamics;; Transcription	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SET domain;; Pre-SET motif	Histone-lysine N-methyltransferase EHMT2 GN=EHMT2 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone-lysine N-methyltransferase EHMT2 isoform X1 [Panthera tigris altaica]
ENSG00000204379(XAGE1A)	--	0.650432	4	0.118949	1	0	0	0	0	0.402528267	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GAGE protein;; GAGE protein	X antigen family member 1 GN=XAGE1E OS=Homo sapiens (Human) PE=2 SV=3	--	--	--
ENSG00000204381(LAYN)	--	0	0	0	0	0	0	2.599461753	109	2.833723092	118	1.39511196	63	0	6.15363039	up	0	6.293742262	up	4.01E-14	5.410726025	up	4.00E-18	Inf	up	--	--	--	K10077|0|hsa:143903|LAYN; layilin; K10077 layilin (A)	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	Layilin (Precursor) GN=LAYN OS=Homo sapiens (Human) PE=2 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: layilin [Pteropus alecto]
ENSG00000204382(XAGE1B)	--	0.221286	1	0	0	0	0	0.202796	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	GAGE protein;; GAGE protein	X antigen family member 1 GN=XAGE1E OS=Homo sapiens (Human) PE=2 SV=3	--	--	--
ENSG00000204385(SLC44A4)	--	0.024355868	1	0.11642142	5	0.060517427	1	0	0	0.047260072	0	0.047997137	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K15377|0|pps:100992063|SLC44A4; solute carrier family 44, member 4; K15377 solute carrier family 44 (choline transporter-like protein), member 2/4/5 (A)"	Choline metabolism in cancer (ko05231)	[I]	Lipid transport and metabolism	Plasma-membrane choline transporter	Choline transporter-like protein 4 GN=SLC44A4 OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: choline transporter-like protein 4 [Galeopterus variegatus]
ENSG00000204386(NEU1)	--	24.9196	916	31.49	1178	28.2206	1055	25.3055	928	22.3703	816	56.393	2076	0.978549511	-0.012035001	normal	0.17887071	-0.550271131	normal	1.25E-06	0.967264973	normal	0.80458614	0.259940064	normal	--	--	--	K01186|0|ptr:471968|NEU1; sialidase 1 (lysosomal sialidase); K01186 sialidase-1 [EC:3.2.1.18] (A)	Other glycan degradation (ko00511);; Sphingolipid metabolism (ko00600);; Lysosome (ko04142)	--	--	BNR repeat-like domain;; BNR repeat-like domain	Sialidase-1 (Precursor) GN=NEU1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sialidase-1 [Pteropus alecto]
ENSG00000204387(C6orf48)	--	71.89673505	848	56.26658817	694	57.7003814	698	63.30234072	795	71.44955055	868	66.97120401	799	0.970355186	-0.12371011	normal	0.896872421	0.30074578	normal	0.957316462	0.1862995	normal	0.636188739	0.115073739	normal	--	--	--	--	--	--	--	--	Protein G8 GN=C6orf48 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	--
ENSG00000204388(HSPA1B)	--	12.4894	681	17.3675	962	22.6149	1265	36.573	2009	21.9923	1204	18.8863	1037	0	1.527816672	up	0.904602731	0.301875081	normal	0.911532889	-0.294623243	normal	0.420974106	0.524798948	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	K03283|0|mcf:101925240|Heat shock 70 kDa protein 1/2; K03283 heat shock 70kDa protein 1/8 (A)	Spliceosome (ko03040);; MAPK signaling pathway (ko04010);; Protein processing in endoplasmic reticulum (ko04141);; Endocytosis (ko04144);; Antigen processing and presentation (ko04612);; Estrogen signaling pathway (ko04915);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Measles (ko05162);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein;; MreB/Mbl protein	Heat shock 70 kDa protein 1A/1B GN=HSPA1B OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 1-like [Odobenus rosmarus divergens]
ENSG00000204389(HSPA1A)	--	21.29169	1147	25.19947	1373	34.73388	1913	66.872	3591	33.68726	1823	26.06086	1420	0	1.614401078	up	0.788311352	0.387185171	normal	0.613697283	-0.437834107	normal	0.499215526	0.600956897	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	K03283|0|mcf:101925240|Heat shock 70 kDa protein 1/2; K03283 heat shock 70kDa protein 1/8 (A)	Spliceosome (ko03040);; MAPK signaling pathway (ko04010);; Protein processing in endoplasmic reticulum (ko04141);; Endocytosis (ko04144);; Antigen processing and presentation (ko04612);; Estrogen signaling pathway (ko04915);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Measles (ko05162);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein;; MreB/Mbl protein	Heat shock 70 kDa protein 1A/1B GN=HSPA1B OS=Homo sapiens (Human) PE=1 SV=5	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 1-like [Odobenus rosmarus divergens]
ENSG00000204390(HSPA1L)	--	1.07053525	55	1.571088	80	1.766767	91	0.79303	40	0.820067	39	1.080082503	56	0.944460656	-0.474646236	normal	0.137278074	-1.029485888	normal	0.648282694	-0.69388943	normal	0.09865505	-0.763072708	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: cell morphogenesis (GO:0000902);; 	"K03283|0|hsa:3305|HSPA1L, HSP70-1L, HSP70-HOM, HSP70T, hum70t; heat shock 70kDa protein 1-like; K03283 heat shock 70kDa protein 1/8 (A)"	Spliceosome (ko03040);; MAPK signaling pathway (ko04010);; Protein processing in endoplasmic reticulum (ko04141);; Endocytosis (ko04144);; Antigen processing and presentation (ko04612);; Estrogen signaling pathway (ko04915);; Legionellosis (ko05134);; Toxoplasmosis (ko05145);; Measles (ko05162);; Influenza A (ko05164);; Epstein-Barr virus infection (ko05169)	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp70 protein;; MreB/Mbl protein	Heat shock 70 kDa protein 1-like GN=HSPA1L OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock 70 kDa protein 1-like [Leptonychotes weddellii]
ENSG00000204392(LSM2)	--	44.1449	458	43.912	464	42.4866	458	41.6527	459	40.3545	418	41.1209	447	0.970556668	-0.027593244	normal	0.953763848	-0.171459316	normal	0.970047145	-0.04321975	normal	0.800513651	-0.081086679	normal	[K]	Transcription	--	K12621|3.11328e-65|cfa:474849|LSM2; uncharacterized LOC474849; K12621 U6 snRNA-associated Sm-like protein LSm2 (A)	RNA degradation (ko03018);; Spliceosome (ko03040)	[A]	RNA processing and modification	LSM domain	U6 snRNA-associated Sm-like protein LSm2 GN=LSM2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	"PREDICTED: uncharacterized protein LOC474849, partial [Canis lupus familiaris]"
ENSG00000204394(VARS)	--	21.7042419	1915	22.47064726	1903	23.36422188	2038	24.46578063	2096	24.33323813	2126	19.20518205	1699	0.984094527	0.09938583	normal	0.980720236	0.138335432	normal	0.944241347	-0.270539449	normal	0.988196733	-0.005696806	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA editing activity (GO:0002161);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01873|0|hsa:7407|VARS, G7A, VARS1, VARS2; valyl-tRNA synthetase (EC:6.1.1.9); K01873 valyl-tRNA synthetase [EC:6.1.1.9] (A)"	Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (I, L, M and V);; Anticodon-binding domain of tRNA;; Glutathione S-transferase, N-terminal domain;; tRNA synthetases class I (M);; Leucyl-tRNA synthetase, Domain 2;; Glutathione S-transferase, C-terminal domain"	Valine--tRNA ligase GN=VARS OS=Homo sapiens (Human) PE=1 SV=4	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: valine--tRNA ligase isoform X2 [Equus przewalskii]
ENSG00000204396(VWA7)	--	0.591786	32	0.641007	35	0.375648	20	0.296604	16	0.647769	35	0.72994	40	0.872718566	-0.964147888	normal	0.982116918	-0.020539115	normal	0.803834054	0.940528502	normal	0.983599773	0.045342215	normal	--	--	--	--	--	[RP]	General function prediction only;; Inorganic ion transport and metabolism	von Willebrand factor type A domain	von Willebrand factor A domain-containing protein 7 (Precursor) GN=VWA7 OS=Homo sapiens (Human) PE=2 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: von Willebrand factor A domain-containing protein 7 [Galeopterus variegatus]
ENSG00000204397(CARD16)	--	0	0	0	0	0	0	0	0	0.09530026	0	0.272918574	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of apoptotic process (GO:0042981);; 	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	Caspase recruitment domain	Caspase recruitment domain-containing protein 16 GN=CARD16 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: caspase-1-like [Balaenoptera acutorostrata scammoni]
ENSG00000204406(MBD5)	--	1.715965401	175	1.331369644	142	1.5312782	128	1.603328514	147	0.985943383	101	1.503171809	153	0.930250927	-0.279687679	normal	0.767145658	-0.506533036	normal	0.944542231	0.246430133	normal	0.713277133	-0.171754208	normal	--	--	--	--	--	--	--	--	Methyl-CpG-binding domain protein 5 GN=MBD5 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: methyl-CpG-binding domain protein 5 isoform X2 [Oryctolagus cuniculus]
ENSG00000204410(MSH5)	--	10.16038612	556	8.953584447	599	7.217798314	517	4.921577007	348	5.383900835	366	7.616582394	437	0.016486995	-0.704345191	normal	0.010091637	-0.729756771	normal	0.926994205	-0.250025962	normal	0.002918783	-0.559407764	normal	[L]	"Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; Biological Process: mismatch repair (GO:0006298);; Molecular Function: mismatched DNA binding (GO:0030983);; 	K08741|0|pps:100995053|MSH5; mutS homolog 5; K08741 DNA mismatch repair protein MSH5 (A)	--	[L]	"Replication, recombination and repair"	MutS domain V;; MutS domain III;; MutS family domain IV	MutS protein homolog 5 GN=MSH5 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: mutS protein homolog 5 isoform X1 [Camelus ferus]
ENSG00000204421(LY6G6C)	--	0.084260273	1	0	0	0	0	0	0	0.08167284	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06846|1.29802e-77|hsa:80740|LY6G6C, C6orf24, G6c, NG24; lymphocyte antigen 6 complex, locus G6C; K06846 lymphocyte antigen 6 complex (A)"	--	--	--	--	Lymphocyte antigen 6 complex locus protein G6c (Precursor) GN=LY6G6C OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: lymphocyte antigen 6 complex locus protein G6c [Vicugna pacos]
ENSG00000204422(XXbac-BPG32J3.20)	--	6.714628848	259	6.17152436	245	6.262040072	249	7.126827653	277	8.138277383	312	8.182103548	318	0.965519409	0.065724583	normal	0.880328055	0.325553266	normal	0.86321021	0.342743251	normal	0.397313214	0.247696603	normal	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: sperm acrosome membrane-associated protein 4-like [Galeopterus variegatus] 
ENSG00000204428(LY6G5C)	--	0.987615313	10	0.443354726	4	0.375394086	3	0.570118314	6	0.830139893	6	0.673272007	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06846|2.94781e-137|ptr:744839|LY6G5C; uncharacterized LOC744839; K06846 lymphocyte antigen 6 complex (A)	--	--	--	--	Lymphocyte antigen 6 complex locus protein G5c (Precursor) GN=LY6G5C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: lymphocyte antigen 6 complex locus protein G5c [Camelus dromedarius]
ENSG00000204435(CSNK2B)	--	81.56535572	1368	80.00053812	1335	85.17638692	1369	78.85468256	1312	79.98287728	1285	65.869161	1142	0.979965036	-0.091028364	normal	0.980199448	-0.076409707	normal	0.933083685	-0.269524779	normal	0.48772198	-0.144635149	normal	[TDK]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Transcription"	Cellular Component: protein kinase CK2 complex (GO:0005956);; Molecular Function: protein kinase regulator activity (GO:0019887);; 	"K03115|5.86167e-164|mcf:102125227|CSNK2B; casein kinase 2, beta polypeptide; K03115 casein kinase II subunit beta (A)"	Ribosome biogenesis in eukaryotes (ko03008);; NF-kappa B signaling pathway (ko04064);; Wnt signaling pathway (ko04310);; Adherens junction (ko04520);; Tight junction (ko04530);; Measles (ko05162);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169)	[TDK]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Transcription"	Casein kinase II regulatory subunit	Casein kinase II subunit beta GN=CSNK2B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: casein kinase II subunit beta isoform 1 [Trichechus manatus latirostris]
ENSG00000204438(GPANK1)	--	7.26220699	196	9.289146102	264	7.074308666	212	6.019196447	211	5.699110931	175	8.083202	250	0.964852848	0.074990466	normal	0.273890617	-0.610283759	normal	0.939577654	0.228072633	normal	0.812661443	-0.100394802	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	--	--	[R]	General function prediction only	G-patch domain;; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	G patch domain and ankyrin repeat-containing protein 1 GN=GPANK1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: G patch domain and ankyrin repeat-containing protein 1 [Galeopterus variegatus] 
ENSG00000204439(C6orf47)	--	6.04492	305	6.0968	318	6.22357	321	5.97679	304	6.57709	327	5.73	289	0.967340841	-0.035391605	normal	0.967130452	0.018749385	normal	0.955340972	-0.159005363	normal	0.885833099	-0.058392167	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4661)	Uncharacterized protein C6orf47 GN=C6orf47 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C6orf47 homolog [Vicugna pacos]
ENSG00000204442(FAM155A)	--	0	0	0.0142613	2	0	0	0.0213764	3	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein FAM155A GN=FAM155A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein FAM155A isoform X1 [Equus caballus]
ENSG00000204444(APOM)	--	1.297532	14	0.783561	8	1.04874	9	1.093231	14	0.9186102	10	1.1754531	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Apolipoprotein M (ApoM)	Apolipoprotein M GN=APOM OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: apolipoprotein M isoform X2 [Galeopterus variegatus]
ENSG00000204463(BAG6)	--	56.42082024	3254	60.10397843	3415	62.07456001	3488	50.19681412	2658	49.71332235	2696	53.63568596	3017	0.923186834	-0.322536561	normal	0.881384118	-0.362310594	normal	0.976104453	-0.217475306	normal	0.066475476	-0.29974804	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF3538);; Ubiquitin family;; Ubiquitin-2 like Rad60 SUMO-like	Large proline-rich protein BAG6 GN=BAG6 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: large proline-rich protein BAG6 isoform 1 [Trichechus manatus latirostris]
ENSG00000204469(PRRC2A)	--	32.0667	5194	31.9339	5154	34.3426	5623	30.9641	4952	31.9752	5145	29.8736	4872	0.992030023	-0.099636773	normal	0.9932803	-0.023940987	normal	0.983481791	-0.215055162	normal	0.607237261	-0.114534598	normal	--	--	--	--	--	[X]	--	BAT2 N-terminus	Protein PRRC2A GN=PRRC2A OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: protein PRRC2A isoform X1 [Loxodonta africana]
ENSG00000204482(LST1)	--	0.143615315	1	1.051846492	4	0	0	0.147486373	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cell morphogenesis (GO:0000902);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	LST-1 protein	Leukocyte-specific transcript 1 protein GN=LST1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: leukocyte-specific transcript 1 protein [Loxodonta africana]
ENSG00000204498(NFKBIL1)	--	6.475242	189	5.883075011	174	5.295998986	165	5.436437	161	5.758497685	161	7.121084	210	0.93467131	-0.259865916	normal	0.959688395	-0.132257788	normal	0.893238027	0.336888684	normal	0.990301572	-0.009670812	normal	--	--	--	K09256|0|ggo:101148301|NFKBIL1; NF-kappa-B inhibitor-like protein 1 isoform 1; K09256 NF-kappa-B inhibitor-like protein 1 (A)	--	--	--	Ankyrin repeats (many copies);; Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ankyrin repeat	NF-kappa-B inhibitor-like protein 1 GN=NFKBIL1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: NF-kappa-B inhibitor-like protein 1 [Felis catus]
ENSG00000204514(ZNF814)	--	4.577019	103	2.317729	89	4.590274	111	2.582486	92	3.599231	100	4.2995248	120	0.962303741	-0.190757909	normal	0.965256558	0.144380839	normal	0.966772126	0.102835517	normal	0.984925516	0.022132284	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:730051|ZNF814; zinc finger protein 814; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Putative uncharacterized zinc finger protein 814 GN=ZNF814 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: putative uncharacterized zinc finger protein 814-like [Pantholops hodgsonii]
ENSG00000204516(MICB)	--	22.37426003	806	22.702093	774	25.5827749	937	16.93180126	601	13.37706433	467	21.15847569	716	0.537614078	-0.453242467	normal	0.004342906	-0.748433838	normal	0.729591309	-0.395648119	normal	0.019687556	-0.517022017	normal	--	--	--	"K07985|0|hsa:4277|MICB, PERB11.2; MHC class I polypeptide-related sequence B; K07985 MHC class I-related protein (A)"	Natural killer cell mediated cytotoxicity (ko04650)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain"	MHC class I polypeptide-related sequence B (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: MHC class I polypeptide-related sequence B-like [Ceratotherium simum simum]
ENSG00000204524(ZNF805)	--	1.30421993	160	1.460827252	206	1.568625483	155	1.256792503	164	1.046250219	150	1.327369793	190	0.967548237	0.004746626	normal	0.722782652	-0.475003515	normal	0.926551716	0.282942385	normal	0.895299876	-0.068995458	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|nle:101176150|ZNF805; zinc finger protein 805; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; Zinc finger, C2H2 type"	Zinc finger protein 805 GN=ZNF805 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 805-like [Ceratotherium simum simum]
ENSG00000204525(HLA-C)	--	46.92423992	835	37.93589335	750	35.09418421	693	89.09939115	1220	84.24775884	1257	48.07448929	920	0.273135931	0.515412029	normal	0.004773972	0.722458576	normal	0.718273374	0.399727572	normal	0.008446504	0.554370388	normal	--	--	Biological Process: immune response (GO:0006955);; Biological Process: antigen processing and presentation (GO:0019882);; 	"K06751|0|hsa:3107|HLA-C, D6S204, HLA-JY3, HLC-C, PSORS1; major histocompatibility complex, class I, C; K06751 major histocompatibility complex, class I (A)"	Endocytosis (ko04144);; Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Natural killer cell mediated cytotoxicity (ko04650);; Type I diabetes mellitus (ko04940);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203);; Autoimmune thyroid disease (ko05320);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain;; MHC_I C-terminus"	"HLA class I histocompatibility antigen, Cw-7 alpha chain (Precursor) GN=HLA-C OS=Homo sapiens (Human) PE=1 SV=3"	U	"Intracellular trafficking, secretion, and vesicular transport"	MHC class I antigen [Equus asinus]
ENSG00000204531(POU5F1)	--	5.179239	271	4.979653624	326	2.590407	266	4.058393138	341	3.937236632	268	4.383361365	346	0.898952124	0.299132084	normal	0.896697323	-0.30251496	normal	0.825377082	0.369208865	normal	0.713453307	0.12464326	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09367|0|ptr:744263|POU5F1, OTF-3, oct-3; POU class 5 homeobox 1; K09367 POU domain transcription factor, class 5 (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 5, transcription factor 1 GN=POU5F1 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	POU class 5 homeobox 1 [Capra hircus] 
ENSG00000204532(ZSCAN5C)	--	0.029006648	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger of C2H2 type;; C2H2-type zinc finger"	Zinc finger and SCAN domain-containing protein 5C GN=ZSCAN5C OS=Homo sapiens (Human) PE=3 SV=1	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 5B-like [Ceratotherium simum simum]
ENSG00000204536(CCHCR1)	--	9.081786604	366	8.288681353	342	7.720036685	336	6.121091978	259	7.336278572	266	5.523000275	261	0.403716165	-0.527078971	normal	0.807183186	-0.382075375	normal	0.824810057	-0.370804055	normal	0.072209827	-0.43074843	normal	--	--	Biological Process: cell differentiation (GO:0030154);; 	K16760|0|mcf:102115497|CCHCR1; coiled-coil alpha-helical rod protein 1; K16760 coiled-coil alpha-helical rod protein 1 (A)	--	--	--	Alpha helical coiled-coil rod protein (HCR)	Coiled-coil alpha-helical rod protein 1 GN=CCHCR1 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	hypothetical protein PANDA_003881 [Ailuropoda melanoleuca]
ENSG00000204538(PSORS1C2)	--	0.160028	3	0	0	0.104329	1	0.429975	8	0.311192	5	0.157165	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Psoriasis susceptibility locus 2	Psoriasis susceptibility 1 candidate gene 2 protein (Precursor) GN=PSORS1C2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: uncharacterized protein LOC102743432 [Leptonychotes weddellii]
ENSG00000204539(CDSN)	--	0.532086	22	0.364735	15	0.0714496	2	0.195906	8	0.351929	14	0.214647	9	0.845770822	-1.330713845	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Corneodesmosin (Precursor) GN=CDSN OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: corneodesmosin [Pteropus alecto]
ENSG00000204540(PSORS1C1)	--	1.3728506	22	2.47057742	22	1.051295939	19	3.281418565	30	1.915665039	21	1.977441746	27	0.979357232	0.393048355	normal	0.987218122	-0.082720092	normal	0.978092763	0.467329488	normal	0.759890361	0.286185877	normal	--	--	--	--	--	--	--	Psoriasis susceptibility 1 candidate 1	Psoriasis susceptibility 1 candidate gene 1 protein GN=PSORS1C1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	--
ENSG00000204542(C6orf15)	--	0.126949	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C6orf15 (Precursor) GN=C6orf15 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C6orf15 homolog [Galeopterus variegatus]
ENSG00000204560(DHX16)	--	11.96409	889	12.98159831	939	13.6100774	1026	11.5895634	841	12.843268	874	11.85088027	825	0.972564802	-0.110713112	normal	0.971176141	-0.124710192	normal	0.875273202	-0.322325228	normal	0.353036293	-0.189175375	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: helicase activity (GO:0004386);; Molecular Function: ATP binding (GO:0005524);; 	K12813|0|mdo:100022458|DHX16; DEAH (Asp-Glu-Ala-His) box polypeptide 16; K12813 pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [EC:3.6.4.13] (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	Oligonucleotide/oligosaccharide-binding (OB)-fold;; Helicase associated domain (HA2);; Helicase conserved C-terminal domain;; DEAD/DEAH box helicase	Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 GN=DHX16 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 [Monodelphis domestica]
ENSG00000204564(C6orf136)	--	7.439879	153	7.357114	148	8.114273	180	6.396439	116	6.306472	123	7.091405	157	0.851245251	-0.425316327	normal	0.9327688	-0.285164009	normal	0.950345158	-0.203689884	normal	0.435551676	-0.30048729	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2358)	Uncharacterized protein C6orf136 GN=C6orf136 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C6orf136 homolog [Tursiops truncatus]
ENSG00000204568(MRPS18B)	--	31.7821	865	30.6403	833	30.8822	839	32.6298	887	30.0514	812	31.7161	868	0.977993606	0.00539225	normal	0.975392844	-0.058156384	normal	0.977130042	0.040660732	normal	0.993341853	-0.004343962	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K16174|4.27873e-169|hsa:28973|MRPS18B, C6orf14, HSPC183, HumanS18a, MRP-S18-2, MRPS18-2, PTD017, S18amt; mitochondrial ribosomal protein S18B; K16174 small subunit ribosomal protein S18b, mitochondrial (A)"	Viral carcinogenesis (ko05203)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S18	"28S ribosomal protein S18b, mitochondrial (Precursor) GN=MRPS18B OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 28S ribosomal protein S18b, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000204569(PPP1R10)	--	20.7542	2078	20.2338	2034	17.6713	1773	18.6122	1856	18.5963	1845	17.5641	1764	0.972459232	-0.193679572	normal	0.977420581	-0.161998892	normal	0.985662564	-0.01562006	normal	0.54003653	-0.128403695	normal	--	--	Cellular Component: nucleus (GO:0005634);; Molecular Function: metal ion binding (GO:0046872);; 	"K17552|0|hsa:5514|PPP1R10, CAT53, FB19, PNUTS, PP1R10, R111, p99; protein phosphatase 1, regulatory subunit 10; K17552 protein phosphatase 1 regulatory subunit 10 (A)"	--	--	--	TFIIS helical bundle-like domain;; Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Serine/threonine-protein phosphatase 1 regulatory subunit 10 GN=PPP1R10 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	serine/threonine-protein phosphatase 1 regulatory subunit 10 [Sus scrofa] 
ENSG00000204572(KRTAP5-10)	--	0	0	0	0	0.208651	2	0.0723499	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: keratin filament (GO:0045095);; 	--	--	--	--	--	--	S	Function unknown	--
ENSG00000204574(ABCF1)	--	22.526294	1925	24.17053567	2099	23.22652734	2064	21.67440126	1929	22.48159782	1953	22.86830291	2002	0.986327153	-0.027815388	normal	0.982013835	-0.125343126	normal	0.986324659	-0.052253562	normal	0.771785816	-0.07021727	normal	[R]	General function prediction only	Molecular Function: ATP binding (GO:0005524);; Molecular Function: ATPase activity (GO:0016887);; 	"K06184|0|hsa:23|ABCF1, ABC27, ABC50; ATP-binding cassette, sub-family F (GCN20), member 1; K06184 ATP-binding cassette, subfamily F, member 1 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	"ABC transporter;; AAA domain;; AAA domain;; NACHT domain;; P-loop containing region of AAA domain;; Protein of unknown function, DUF258;; ABC transporter;; ATPase family associated with various cellular activities (AAA);; Molybdopterin guanine dinucleotide synthesis protein B;; RNA helicase;; AAA domain (dynein-related subfamily)"	ATP-binding cassette sub-family F member 1 GN=ABCF1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ATP-binding cassette sub-family F member 1 isoform 1 [Ceratotherium simum simum]
ENSG00000204576(PRR3)	--	9.38559	262	7.89923	242	11.24733	319	10.88824	305	11.80546	316	10.40059	297	0.949232348	0.187390977	normal	0.842635024	0.361508849	normal	0.962367818	-0.110840227	normal	0.687403217	0.136814113	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	--	--	Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Proline-rich protein 3 GN=PRR3 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: proline-rich protein 3 [Physeter catodon]
ENSG00000204577(LILRB3)	--	0.015628152	1	0	0	0.015191875	0	0.03136923	2	0.046191202	1	0.015411415	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06512|0|hsa:11025|LILRB3, CD85A, HL9, ILT-5, ILT5, LILRA6, LIR-3, LIR3, PIRB; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3; K06512 leukocyte immunoglobulin-like receptor (A)"	Osteoclast differentiation (ko04380);; B cell receptor signaling pathway (ko04662)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain	Leukocyte immunoglobulin-like receptor subfamily B member 3 (Precursor) GN=LILRB3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 3 isoform X3 [Galeopterus variegatus]
ENSG00000204580(DDR1)	--	37.70653192	2159	40.73214265	2337	31.09340297	1991	39.69430955	2118	43.29559643	2319	34.673742	2092	0.986613993	-0.058450919	normal	0.98765149	-0.03256032	normal	0.986024656	0.063051464	normal	0.972519923	-0.012091491	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05124|0|pon:100443857|DDR1; discoidin domain receptor tyrosine kinase 1; K05124 discoidin domain receptor family member 1 [EC:2.7.10.1] (A)	--	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; F5/8 type C domain	Epithelial discoidin domain-containing receptor 1 (Precursor) GN=DDR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: epithelial discoidin domain-containing receptor 1 isoform X2 [Galeopterus variegatus]
ENSG00000204590(GNL1)	--	14.15405523	929	10.40862146	804	12.76054048	945	10.9877768	813	11.19346131	973	11.76015083	860	0.94784197	-0.222861128	normal	0.934306293	0.253383959	normal	0.968934111	-0.144027402	normal	0.89741169	-0.038100861	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[R]	General function prediction only	50S ribosome-binding GTPase	Guanine nucleotide-binding protein-like 1 GN=GNL1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	guanine nucleotide-binding protein-like 1 [Sus scrofa] 
ENSG00000204592(HLA-E)	--	27.88	1500	21.841	1201	21.7208	1191	35.0715	1898	40.6584	2168	35.8526	1931	0.912529586	0.308403873	normal	0.000169878	0.829913503	normal	0.007124652	0.688190515	normal	2.18E-05	0.602486606	normal	--	--	Biological Process: immune response (GO:0006955);; Biological Process: antigen processing and presentation (GO:0019882);; 	"K06751|0|hsa:3133|HLA-E, EA1.2, EA2.1, HLA-6.2, MHC, QA1; major histocompatibility complex, class I, E; K06751 major histocompatibility complex, class I (A)"	Endocytosis (ko04144);; Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Natural killer cell mediated cytotoxicity (ko04650);; Type I diabetes mellitus (ko04940);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203);; Autoimmune thyroid disease (ko05320);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain;; CD80-like C2-set immunoglobulin domain"	"HLA class I histocompatibility antigen, alpha chain E (Precursor) GN=HLA-E OS=Homo sapiens (Human) PE=1 SV=3"	R	General function prediction only	"PREDICTED: LOW QUALITY PROTEIN: HLA class I histocompatibility antigen, B-14 alpha chain-like [Equus przewalskii]"
ENSG00000204599(TRIM39)	--	42.853172	396	39.586215	443	47.86799205	455	40.48634318	424	47.320813	430	40.25364796	432	0.967819704	0.067478538	normal	0.967828502	-0.064174223	normal	0.967524684	-0.082844053	normal	0.940905081	-0.029947773	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: intracellular (GO:0005622);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; Molecular Function: metal ion binding (GO:0046872);; 	"K12015|0|hsa:56658|TRIM39, RNF23, TFP, TRIM39B; tripartite motif containing 39; K12015 tripartite motif-containing protein 39 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Ring finger domain;; zinc-RING finger domain;; RING-type zinc-finger"	E3 ubiquitin-protein ligase TRIM39 GN=TRIM39 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	tripartite motif-containing protein 39 [Sus scrofa] 
ENSG00000204610(TRIM15)	--	0	0	0	0	0	0	0.024156603	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: intracellular (GO:0005622);; Biological Process: lipid transport (GO:0006869);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; Molecular Function: metal ion binding (GO:0046872);; 	"K12005|0|hsa:89870|TRIM15, RNF93, ZNF178, ZNFB7; tripartite motif containing 15; K12005 tripartite motif-containing protein 15 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 15 GN=TRIM15 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 15 isoform X1 [Bubalus bubalis] 
ENSG00000204611(ZNF616)	--	0.66481799	51	0.7495727	50	0.922593769	63	1.139671075	76	1.2875712	111	2.687694678	134	0.891447765	0.531479795	normal	0.014674288	1.106125993	normal	0.008240566	1.062629791	up	0.019405002	0.949789215	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:90317|ZNF616; zinc finger protein 616; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Exportin 1-like protein;; CS domain"	Zinc finger protein 616 GN=ZNF616 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 665-like [Ursus maritimus]
ENSG00000204613(TRIM10)	--	0	0	0	0	0	0	0	0	0.040598061	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12002|0|hsa:10107|TRIM10, HERF1, RFB30, RNF9; tripartite motif containing 10; K12002 tripartite motif-containing protein 10 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	Tripartite motif-containing protein 10 GN=TRIM10 OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 10 [Loxodonta africana]
ENSG00000204616(TRIM31)	--	0.162805405	7	0.024632861	1	0.02428383	0	0.917753516	40	2.0070207	86	3.149733057	136	0.002209654	2.255180947	up	0	5.107632471	up	0	6.502589083	up	0.000163804	5.013371426	up	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12011|0|hsa:11074|TRIM31, C6orf13, HCG1, HCGI, RNF; tripartite motif containing 31; K12011 tripartite motif-containing protein 31 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"zinc finger of C3HC4-type, RING;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase TRIM31 GN=TRIM31 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM31 [Equus przewalskii]
ENSG00000204618(RNF39)	--	0.849634	30	0.607101	22	0.403768	14	0.646673	23	1.3408	47	0.781394	28	0.978875131	-0.391209356	normal	0.603035108	1.024531806	normal	0.920828438	0.920229453	normal	0.486499241	0.549026638	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY-associated domain;; SPRY domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 39 GN=RNF39 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: LOW QUALITY PROTEIN: RING finger protein 39, partial [Equus przewalskii]"
ENSG00000204619(PPP1R11)	--	22.70761743	719	22.60432674	725	20.56348855	662	21.48806475	686	20.56095446	656	21.73439169	701	0.97109935	-0.098400152	normal	0.960549154	-0.16534896	normal	0.972796604	0.074127208	normal	0.823164267	-0.06511565	normal	--	--	--	K17553|4.03047e-46|mcf:101925924|uncharacterized LOC101925924; K17553 protein phosphatase 1 regulatory subunit 11 (A)	--	[S]	Function unknown	Protein phosphatase inhibitor	Protein phosphatase 1 regulatory subunit 11 GN=PPP1R11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	protein phosphatase 1 regulatory subunit 11 [Sus scrofa] 
ENSG00000204624(DISP3)	--	0.054014077	5	0.044285704	1	0	0	0	0	0.0470433	2	0.0426282	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[T]	Signal transduction mechanisms	Patched family;; MMPL family;; Sterol-sensing domain of SREBP cleavage-activation	Patched domain-containing protein 2 GN=PTCHD2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: patched domain-containing protein 2 [Equus przewalskii]
ENSG00000204628(RACK1)	--	1368.405726	17931	1328.452129	16797	1330.365366	16972	1416.253295	18237	1388.297826	18109	1309.275824	17097	0.997735488	-0.006419242	normal	0.99712362	0.087069187	normal	0.997589771	0.002294969	normal	0.938716194	0.026442053	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14753|0|myd:102754545|GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; K14753 guanine nucleotide-binding protein subunit beta-2-like 1 protein (A)"	Measles (ko05162)	[T]	Signal transduction mechanisms	"WD domain, G-beta repeat;; Eukaryotic translation initiation factor eIF2A"	"Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed GN=GNB2L1 OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein subunit beta-2-like 1 [Myotis davidii]
ENSG00000204634(TBC1D8)	--	31.7213	2462	32.4788	2552	28.1497	2207	11.15891	864	14.91363	1150	15.29262	1183	0	-1.539859588	down	6.15E-10	-1.170359337	down	9.26E-06	-0.907065005	normal	4.39E-19	-1.195921946	down	--	--	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain;; GRAM domain	TBC1 domain family member 8 GN=TBC1D8 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: TBC1 domain family member 8 isoform X2 [Mustela putorius furo]
ENSG00000204642(HLA-F)	--	2.989270449	68	1.05553956	30	1.632026	42	2.841738	71	4.404214492	112	2.051092	49	0.974950171	0.030771595	normal	8.93E-07	1.828092378	up	0.975780045	0.207188273	normal	0.375896189	0.706881194	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K06751|0|ptr:100169977|PATR-F, MHC-F; major histocompatibility complex, class I, F; K06751 major histocompatibility complex, class I (A)"	Endocytosis (ko04144);; Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Type I diabetes mellitus (ko04940);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203);; Autoimmune thyroid disease (ko05320);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain"	"HLA class I histocompatibility antigen, alpha chain F (Precursor) GN=HLA-F OS=Homo sapiens (Human) PE=2 SV=3"	W	Extracellular structures	"MHC class I antigen, partial [Equus caballus]"
ENSG00000204644(ZFP57)	--	0	0	0	0	0.050779579	1	0.096724239	4	0.068325692	2	0.119705006	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:346171|ZFP57, C6orf40, TNDM1, ZNF698, bA145L22, bA145L22.2; ZFP57 zinc finger protein; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 57 homolog GN=ZFP57 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	"PREDICTED: zinc finger protein 57 homolog, partial [Ceratotherium simum simum]"
ENSG00000204653(ASPDH)	--	0	0	1.12643	1	0.124133	0	0	0	0.128101	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Biological Process: NADP catabolic process (GO:0006742);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: pyridine nucleotide biosynthetic process (GO:0019363);; Molecular Function: NADP binding (GO:0050661);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	--	--	"Domain of unknown function DUF108;; Homoserine dehydrogenase, NAD binding domain"	Putative L-aspartate dehydrogenase GN=ASPDH OS=Homo sapiens (Human) PE=2 SV=2	C	Energy production and conversion	PREDICTED: putative L-aspartate dehydrogenase [Galeopterus variegatus]
ENSG00000204657(OR2H2)	--	0	0	0.0802659	2	0.197723	4	0.0399462	1	0	0	0.0394703	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:7932|OR2H2, FAT11, OLFR2, OLFR42B, OR2H3, dJ271M21.2, hs6M1-12; olfactory receptor, family 2, subfamily H, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srv	Olfactory receptor 2H2 GN=OR2H2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 2H2-like [Chrysochloris asiatica]
ENSG00000204659(CBY3)	--	0.236803	2	0.115893	1	0	0	0.226239	2	0	0	0.228147	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Chibby family	Protein chibby homolog 3 GN=CBY3 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: protein chibby homolog 3 [Galeopterus variegatus]
ENSG00000204671(IL31)	--	0	0	0	0	0	0	0	0	0	0	0.0797669	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Interleukin 31	Interleukin-31 (Precursor) GN=IL31 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: interleukin-31 [Galeopterus variegatus]
ENSG00000204673(AKT1S1)	--	67.123921	2320	76.289029	2722	72.373281	2552	66.77765459	2355	62.7410315	2235	73.506838	2661	0.988239137	-0.009223946	normal	0.932207331	-0.305631056	normal	0.988547982	0.05201855	normal	0.702729366	-0.087545423	normal	--	--	Biological Process: negative regulation of TOR signaling (GO:0032007);; Biological Process: neurotrophin TRK receptor signaling pathway (GO:0048011);; 	K16184|1.79295e-127|ggo:101151809|AKT1S1; proline-rich AKT1 substrate 1 isoform 1; K16184 proline-rich AKT1 substrate 1 (A)	mTOR signaling pathway (ko04150);; AMPK signaling pathway (ko04152)	--	--	--	Proline-rich AKT1 substrate 1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: proline-rich AKT1 substrate 1 [Physeter catodon]
ENSG00000204681(GABBR1)	--	5.445087154	577	3.991476742	462	4.656003	529	3.455236782	336	4.337628	474	4.3302916	430	0.00155731	-0.808085651	normal	0.970267384	0.015517504	normal	0.886024022	-0.30624962	normal	0.109006295	-0.358887061	normal	[E]	Amino acid transport and metabolism	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04615|0|cjc:100397234|GABBR1; gamma-aminobutyric acid (GABA) B receptor, 1; K04615 gamma-aminobutyric acid type B receptor (A)"	cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; GABAergic synapse (ko04727);; Estrogen signaling pathway (ko04915);; Morphine addiction (ko05032)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	Receptor family ligand binding region;; 7 transmembrane sweet-taste receptor of 3 GCPR;; Periplasmic binding protein;; Sushi domain (SCR repeat)	Gamma-aminobutyric acid type B receptor subunit 1 (Precursor) GN=GABBR1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid type B receptor subunit 1 isoform 1 [Ceratotherium simum simum]
ENSG00000204682(CASC10)	--	11.56434	1046	13.95207	1288	12.96746	1140	8.218674	678	10.05481	831	7.62347	694	0.021145148	-0.655152376	normal	0.023759721	-0.652676581	normal	0.004013968	-0.723075416	normal	6.76E-06	-0.678233574	normal	--	--	--	--	--	--	--	--	Protein CASC10 GN=CASC10 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC101112588 [Ovis aries]
ENSG00000204688(OR2H1)	--	0	0	0	0	0	0	0	0	0.048334755	0	0.048776939	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:26716|OR2H1, 6M1-16, HS6M1-16, OLFR42A-9004-14, OR2H6, OR2H8, OR6-2, dJ994E9.4; olfactory receptor, family 2, subfamily H, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 2H1 GN=OR2H1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 2H1 [Equus przewalskii]
ENSG00000204694(OR11A1)	--	0	0	0	0	0	0	0	0	0	0	0.036668988	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:26531|OR11A1, 6M1-18, OR11A2, dJ994E9.6, hs6M1-18; olfactory receptor, family 11, subfamily A, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 11A1 GN=OR11A1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 11A1 [Oryctolagus cuniculus]
ENSG00000204711(C9orf135)	--	0	0	0	0	0	0	0	0	0	0	0.093925336	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4572)	Uncharacterized protein C9orf135 GN=C9orf135 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C9orf135 homolog [Ceratotherium simum simum]
ENSG00000204713(TRIM27)	--	18.31315	956	16.1614127	853	17.927824	944	21.505825	1123	24.92706856	1294	22.5368877	1177	0.95865768	0.201144642	normal	0.108689838	0.578954463	normal	0.894357519	0.309519197	normal	0.026965848	0.363699362	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12009|0|ptr:739369|TRIM27, RFP; tripartite motif containing 27; K12009 tripartite motif-containing protein 27 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; B-box zinc finger;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger)"	Zinc finger protein RFP GN=TRIM27 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: zinc finger protein RFP [Galeopterus variegatus]
ENSG00000204740(MALRD1)	--	0.164289101	5	0.130536017	4	0.194286042	5	0.076886959	3	0.141725225	8	0.082417076	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	MAM domain;; Low-density lipoprotein receptor domain class A;; EGF-like domain	MAM and LDL-receptor class A domain-containing protein 1 GN=MALRD1 OS=Homo sapiens (Human) PE=3 SV=3	S	Function unknown	PREDICTED: MAM and LDL-receptor class A domain-containing protein 1 [Balaenoptera acutorostrata scammoni]
ENSG00000204764(RANBP17)	--	2.902688084	185	3.3424272	174	3.669866409	191	2.80576748	186	2.126298	164	2.229932474	174	0.966943506	-0.022865528	normal	0.962082436	-0.105870073	normal	0.959383192	-0.141601649	normal	0.84878724	-0.091180055	normal	--	--	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Importin-beta N-terminal domain	Ran-binding protein 17 GN=RANBP17 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ran-binding protein 17 [Lipotes vexillifer]
ENSG00000204767(FAM196B)	--	0.327111	24	0.2445105	17	0.2525655	15	1.010756	68	0.729574	50	0.384478	26	0.013359754	1.415646508	normal	0.06436665	1.45619665	normal	0.961424153	0.728852221	normal	0.06816725	1.338292089	normal	--	--	--	--	--	--	--	FAM196 family	Protein FAM196B GN=FAM196B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM196B [Tupaia chinensis] 
ENSG00000204779(FOXD4L5)	--	0.0383431	2	0.0948723	5	0.12994	6	0.152929	8	0.259267	13	0.11313	6	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	Fork head domain	Forkhead box protein D4-like 5 GN=FOXD4L5 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: forkhead box protein D4-like [Equus przewalskii]
ENSG00000204815(TTC25)	--	1.08119	55	1.08111003	49	0.63189878	35	0.754136	36	0.886571	45	1.056654	53	0.899199214	-0.620671089	normal	0.976506351	-0.139779978	normal	0.924132479	0.570194674	normal	0.945420517	-0.073497732	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 25 GN=TTC25 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 25 [Ceratotherium simum simum]
ENSG00000204822(MRPL53)	--	48.70323	679	49.94848	741	56.8035	848	39.41445	580	42.3385	600	39.8593	576	0.925051869	-0.257559534	normal	0.867485023	-0.325198495	normal	0.143934087	-0.565056378	normal	0.031110768	-0.390005043	normal	--	--	--	"K17434|1.19113e-76|hsa:116540|MRPL53, L53MT; mitochondrial ribosomal protein L53; K17434 large subunit ribosomal protein L53 (A)"	--	--	--	39S ribosomal protein L53/MRP-L53	"39S ribosomal protein L53, mitochondrial (Precursor) GN=MRPL53 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L53, mitochondrial [Orcinus orca] "
ENSG00000204839(MROH6)	--	3.892905984	148	4.212021798	210	3.274888709	168	3.548140081	183	3.662116944	186	4.436974969	221	0.93194051	0.27286305	normal	0.948589367	-0.195019897	normal	0.847871308	0.384268869	normal	0.729785971	0.144830898	normal	--	--	--	--	--	--	--	--	Maestro heat-like repeat-containing protein family member 6 GN=MROH6 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: maestro heat-like repeat-containing protein family member 6 [Orycteropus afer afer]
ENSG00000204842(ATXN2)	--	18.50327801	1270	21.30973501	1446	24.5274909	1564	18.33880077	1205	16.874446	1216	17.31839048	1226	0.977756809	-0.106495321	normal	0.934602735	-0.27104132	normal	0.833166638	-0.359179696	normal	0.149976183	-0.251799647	normal	--	--	--	--	--	[A]	RNA processing and modification	Ataxin 2 SM domain;; LsmAD domain;; Ataxin-2 C-terminal region	Ataxin-2 GN=ATXN2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: ataxin-2 [Pteropus alecto]
ENSG00000204843(DCTN1)	--	48.51213381	4885	48.023834	4883	52.06690259	5425	35.89226307	3527	35.28414525	3494	33.2914022	3338	0.424579351	-0.50056304	normal	0.438576429	-0.504129217	normal	0.004370035	-0.708676238	normal	7.89E-05	-0.573673717	normal	[D]	"Cell cycle control, cell division, chromosome partitioning"	--	K04648|0|ptr:459332|DCTN1; dynactin 1; K04648 dynactin 1 (A)	Vasopressin-regulated water reabsorption (ko04962);; Huntington's disease (ko05016)	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Dynein associated protein;; CAP-Gly domain	Dynactin subunit 1 GN=DCTN1 OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: dynactin subunit 1 isoform X1 [Equus przewalskii]
ENSG00000204849(SPATA31A1)	--	0.0105996	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM75 family;; Domain of unknown function (DUF4599)	Spermatogenesis-associated protein 31A1 GN=SPATA31A1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: spermatogenesis-associated protein 31A6-like [Balaenoptera acutorostrata scammoni]
ENSG00000204852(TCTN1)	--	17.07755643	567	13.39056929	462	16.53163806	529	21.5755581	763	24.47684164	766	23.115933	686	0.727847858	0.396572797	normal	0.011838312	0.706211764	normal	0.800694454	0.365728826	normal	0.005569502	0.486228589	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1619)	Tectonic-1 (Precursor) GN=TCTN1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: tectonic-1 [Galeopterus variegatus]
ENSG00000204856(FAM216A)	--	8.19201	232	8.23991	234	9.78333	279	10.106	289	7.58901	215	5.84711	167	0.912800057	0.284422078	normal	0.956958359	-0.142636366	normal	0.041695921	-0.743442058	normal	0.687987147	-0.173478958	normal	--	--	--	--	--	--	--	FAM216B protein family	Protein FAM216A GN=FAM216A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM216A isoform X1 [Mustela putorius furo] 
ENSG00000204859(ZBTB48)	--	3.768120249	213	3.999575002	276	5.059223104	274	3.935111367	229	3.129625818	196	4.486730196	273	0.964866044	0.073152957	normal	0.549438026	-0.51189539	normal	0.967404604	-0.013491783	normal	0.678215225	-0.149024884	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10519|0|hsa:3104|ZBTB48, HKR3, ZNF855, pp9964; zinc finger and BTB domain containing 48; K10519 zinc finger and BTB domain-containing protein 48 (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; BTB/POZ domain;; Drought induced 19 protein (Di19), zinc-binding;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger and BTB domain-containing protein 48 GN=ZBTB48 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger and BTB domain-containing protein 48 isoform X1 [Galeopterus variegatus]
ENSG00000204866(IGFL2)	--	0.0808384	1	0	0	0	0	0.842918274	6	0.394598	4	0.400056	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Insulin growth factor-like family	Insulin growth factor-like family member 2 (Precursor) GN=IGFL2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: IGF-like family member 3 isoform X4 [Canis lupus familiaris]
ENSG00000204869(IGFL4)	--	8.768150189	658	5.590286275	425	7.83885203	554	5.608945894	433	9.682100072	713	8.883733688	634	0.052614856	-0.632717005	normal	0.009101215	0.723005616	normal	0.954137118	0.185830905	normal	0.867890036	0.100954158	normal	--	--	--	--	--	--	--	Insulin growth factor-like family	Insulin growth factor-like family member 4 (Precursor) GN=IGFL4 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"PREDICTED: insulin growth factor-like family member 4, partial [Orycteropus afer afer]"
ENSG00000204882(GPR20)	--	0.472258	9	0.203089	4	0.59333	11	0.205884	4	0.252806	4	0.822624	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04317|0|hsa:2843|GPR20; G protein-coupled receptor 20; K04317 G protein-coupled receptor 20 (A)	--	--	--	7 transmembrane receptor (rhodopsin family)	G-protein coupled receptor 20 GN=GPR20 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 20 [Galeopterus variegatus]
ENSG00000204889(KRT40)	--	0	0	0	0	0	0	0	0	0	0	0.026558417	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K07604|0|hsa:125115|KRT40, CK-40, K40, KA36; keratin 40; K07604 type I keratin, acidic (A)"	--	--	--	Intermediate filament protein	"Keratin, type I cytoskeletal 40 GN=KRT40 OS=Homo sapiens (Human) PE=1 SV=2"	Z	Cytoskeleton	"PREDICTED: keratin, type I cytoskeletal 40 [Equus przewalskii]"
ENSG00000204899(MZT1)	--	19.1557	485	21.9317	555	20.8075	514	18.491	480	13.5628	345	18.2372	464	0.970453418	-0.045637277	normal	0.019198327	-0.704857717	normal	0.95891938	-0.155453378	normal	0.1872737	-0.291228815	normal	--	--	--	K18633|4.17275e-39|ptr:735745|MZT1; mitotic spindle organizing protein 1; K18633 mitotic-spindle organizing protein 1 (A)	--	--	--	Mitotic-spindle organizing gamma-tubulin ring associated	Mitotic-spindle organizing protein 1 GN=MZT1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: mitotic-spindle organizing protein 1 [Dasypus novemcinctus]
ENSG00000204922(UQCC3)	--	16.30963	543	16.66225	571	19.06356	651	17.88311	612	20.18544	685	16.43584	562	0.963126403	0.141370263	normal	0.93439142	0.240604224	normal	0.943285644	-0.219828708	normal	0.866293268	0.053782143	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4574)	Ubiquinol-cytochrome-c reductase complex assembly factor 3 {ECO:0000312|HGNC:HGNC:34399} GN=UNQ655/PRO1286 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: ubiquinol-cytochrome-c reductase complex assembly factor 3 [Felis catus]
ENSG00000204923(FBXO48)	--	0.947902649	83	1.101949989	94	0.985407088	83	0.53432659	47	0.760119338	67	0.757939379	67	0.440588385	-0.830568698	normal	0.866239341	-0.500344044	normal	0.952264911	-0.310924104	normal	0.238319265	-0.542751741	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	F-box-like;; F-box domain	F-box only protein 48 GN=FBXO48 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: F-box only protein 48 [Odobenus rosmarus divergens] 
ENSG00000204928(GRXCR2)	--	0	0	0.0781888	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Glutaredoxin domain-containing cysteine-rich protein 2 GN=GRXCR2 OS=Homo sapiens (Human) PE=3 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutaredoxin domain-containing cysteine-rich protein 2 [Myotis davidii]
ENSG00000204930(FAM221B)	--	0	0	0	0	0	0	0.043676926	3	0	0	0.043791515	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4475)	Protein FAM221B GN=FAM221B OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM221B [Ceratotherium simum simum]
ENSG00000204936(CD177)	--	0	0	0	0	0	0	0.0457063	2	0.067054	2	0.1809211	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06552|0|hsa:57126|CD177, HNA-2a, HNA2A, NB1, NB1_GP, PRV-1, PRV1; CD177 molecule; K06552 CD177 antigen (A)"	--	--	--	u-PAR/Ly-6 domain	CD177 antigen (Precursor) GN=CD177 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: CD177 antigen [Galeopterus variegatus]
ENSG00000204941(PSG5)	--	0	0	0.0249312	1	0.397632396	5	0.330536543	10	0.205636317	5	0.037888925	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Alphaherpesvirus glycoprotein E	Pregnancy-specific beta-1-glycoprotein 3 (Precursor) GN=PSG3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1-like [Panthera tigris altaica]
ENSG00000204946(ZNF783)	--	6.93867751	789	6.242240214	758	5.4095635	630	5.244721738	583	6.225028	698	7.508242982	909	0.488212473	-0.466300757	normal	0.965901617	-0.140105971	normal	0.274033408	0.519593052	normal	0.985435375	-0.01160881	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:100289678|ZNF783; zinc finger family member 783; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; KRAB box;; Zinc-finger double domain;; Zinc finger protein;; C2H2-type zinc finger"	Protein ZNF783 GN=ZNF783 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 777-like [Equus caballus]
ENSG00000204947(ZNF425)	--	0.692403945	47	0.8999657	58	0.797483288	55	0.630163165	43	0.656191275	44	0.828291411	57	0.978299363	-0.153894402	normal	0.950689858	-0.407729819	normal	0.977208692	0.042101679	normal	0.823286826	-0.172318318	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:155054|ZNF425; zinc finger protein 425; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; KRAB box;; Zinc-finger of C2H2 type"	Zinc finger protein 425 GN=ZNF425 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 425 isoform X2 [Galeopterus variegatus]
ENSG00000204950(LRRC10B)	--	0	0	0.0837384	3	0.108973	3	0.0287878	1	0.225151	7	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine Rich repeats (2 copies);; Leucine rich repeat;; Leucine Rich Repeat;; Leucine rich repeat	Leucine-rich repeat-containing protein 10B GN=LRRC10B OS=Homo sapiens (Human) PE=4 SV=2	S	Function unknown	PREDICTED: leucine-rich repeat-containing protein 10B [Equus przewalskii] 
ENSG00000204952(FBXO47)	--	0.0820339	3	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	K10321|0|hsa:494188|FBXO47; F-box protein 47; K10321 F-box protein 47 (A)	--	--	--	F-box domain	F-box only protein 47 GN=FBXO47 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: F-box only protein 47 [Pteropus alecto]
ENSG00000204954(C12orf73)	--	7.86147826	129	11.594322	169	7.888702424	131	9.111395001	142	8.13643451	137	10.334307	145	0.965103796	0.106478607	normal	0.91258422	-0.321076315	normal	0.962379797	0.136694182	normal	0.955958996	-0.038339931	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4516)	Uncharacterized protein C12orf73 (Precursor) GN=C12orf73 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C12orf73 homolog [Ceratotherium simum simum]
ENSG00000204978(ERICH4)	--	0.0578891	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4530)	Glutamate-rich protein 4 GN=ERICH4 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C19orf69-like [Pantholops hodgsonii]
ENSG00000204991(SPIRE2)	--	9.28475352	525	9.517370217	542	8.981790055	527	6.013654851	340	5.53188928	313	6.943474043	379	0.046931934	-0.655211736	normal	0.002141511	-0.810541502	normal	0.480479893	-0.482257073	normal	0.000563039	-0.648142727	normal	--	--	--	"K02098|0|hsa:84501|SPIRE2, Spir-2; spire-type actin nucleation factor 2; K02098 spire (A)"	Dorso-ventral axis formation (ko04320)	--	--	--	Protein spire homolog 2 GN=SPIRE2 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein spire homolog 2 [Ceratotherium simum simum]
ENSG00000205002(AARD)	--	0.355979	14	0.124004	5	0.197143	7	0	0	0.0245442	0	0.075041	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Alanine and arginine-rich domain-containing protein GN=AARD OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: alanine and arginine-rich domain-containing protein [Ceratotherium simum simum]
ENSG00000205038(PKHD1L1)	--	0.063213506	4	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"IPT/TIG domain;; G8 domain;; Right handed beta helix region;; PA14 domain;; Quinohemoprotein amine dehydrogenase, alpha subunit domain III"	Fibrocystin-L (Precursor) GN=PKHD1L1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: fibrocystin-L [Equus caballus]
ENSG00000205057(CLLU1OS)	--	0	0	0	0	0	0	0.0990557	1	0.199105	1	0.300054	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative chronic lymphocytic leukemia up-regulated protein 1 opposite strand transcript protein GN=CLLU1OS OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	--
ENSG00000205060(SLC35B4)	--	18.887173	1990	18.96516824	2060	18.187613	1870	20.89361968	2328	22.742501	2339	21.850477	2365	0.973685926	0.195350814	normal	0.979224305	0.161709502	normal	0.899260955	0.33027245	normal	0.195175416	0.227051957	normal	--	--	Biological Process: transmembrane transport (GO:0055085);; 	"K15278|0|ptr:463743|SLC35B4, PLEKHM3; solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4; K15278 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 (A)"	--	[G]	Carbohydrate transport and metabolism	UAA transporter family;; Triose-phosphate Transporter family	UDP-xylose and UDP-N-acetylglucosamine transporter GN=SLC35B4 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-xylose and UDP-N-acetylglucosamine transporter [Equus caballus] 
ENSG00000205084(TMEM231)	--	5.320301643	241	4.283093082	215	4.7663825	214	6.615279322	341	6.580946427	296	7.402127291	334	0.620298795	0.467390427	normal	0.72674736	0.437203074	normal	0.149521497	0.630351809	normal	0.031748093	0.513907981	normal	--	--	--	--	--	[S]	Function unknown	Transmembrane protein 231;; Transmembrane protein 231	Transmembrane protein 231 GN=TMEM231 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 231 isoform X1 [Canis lupus familiaris]
ENSG00000205085(FAM71F2)	--	0.20161596	8	0.226578299	9	0.277616485	5	0.199124547	8	0.55723	14	0.582497182	20	--	--	--	--	--	--	0.687395658	1.716887483	normal	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF3699)	Protein FAM71F2 GN=FAM71F2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM71F2 [Ceratotherium simum simum]
ENSG00000205086(C2orf91)	--	0	0	0	0	0.0284725	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf91 GN=C2orf91 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C2orf91 homolog [Balaenoptera acutorostrata scammoni]
ENSG00000205089(CCNI2)	--	0.0811866	3	0.167512	7	0.118781	4	0.0803109	3	0.262542	9	0.0534415	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-I2 GN=CCNI2 OS=Homo sapiens (Human) PE=2 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-I2 [Oryctolagus cuniculus]
ENSG00000205090(TMEM240)	--	0.29874494	3	1.027680358	11	0.086986673	0	0.662821834	7	0.946446	9	0.581092433	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMEM240 family	Transmembrane protein 240 GN=TMEM240 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 240 [Canis lupus familiaris] 
ENSG00000205097(FRG2)	--	0.084402335	3	0.02806259	1	0	0	0.084027793	3	0.081074544	2	0.08358205	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Facioscapulohumeral muscular dystrophy candidate 2	Protein FRG2 GN=FRG2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FRG2-like-1 [Galeopterus variegatus]
ENSG00000205108(FAM205A)	--	0.0209825	2	0.0106627	1	0	0	0.0106613	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4599);; FAM75 family	Protein FAM205A GN=FAM205A OS=Homo sapiens (Human) PE=2 SV=4	S	Function unknown	PREDICTED: protein FAM205A [Leptonychotes weddellii]
ENSG00000205111(CDKL4)	--	0.0401826	1	0	0	0	0	0.056153876	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08824|0|ptr:735724|CDKL4; cyclin-dependent kinase-like 4; K08824 cyclin-dependent kinase-like [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase-like 4 GN=CDKL4 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: cyclin-dependent kinase-like 4 [Condylura cristata]
ENSG00000205116(TMEM88B)	--	0.228541	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 88B GN=TMEM88B OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: transmembrane protein 88B [Trichechus manatus latirostris]
ENSG00000205129(C4orf47)	--	0.123597	3	0	0	0.402270351	7	0.196362076	4	0.098660646	1	0.150514	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4586)	UPF0602 protein C4orf47 GN=C4orf47 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0602 protein C4orf47 homolog isoform X1 [Mustela putorius furo] 
ENSG00000205133(TRIQK)	--	12.46282656	425	12.73715628	369	9.91932932	372	14.13581272	425	12.93956221	403	10.41945385	402	0.969787838	-0.030721203	normal	0.963328488	0.105319358	normal	0.964505819	0.103197782	normal	0.879339328	0.055636924	normal	--	--	--	--	--	--	--	Triple QxxK/R motif-containing protein family	Triple QxxK/R motif-containing protein GN=TRIQK OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: triple QxxK/R motif-containing protein isoform X1 [Bos taurus] 
ENSG00000205138(SDHAF1)	--	24.953	459	22.481	431	24.406	473	29.1539	548	28.3824	523	25.741	481	0.939185782	0.224162084	normal	0.92289414	0.256877238	normal	0.971267439	0.015855	normal	0.52259649	0.165894061	normal	--	--	--	"K18167|1.12479e-61|hsa:644096|SDHAF1, LYRM8; succinate dehydrogenase complex assembly factor 1; K18167 succinate dehydrogenase assembly factor 1 (A)"	--	[S]	Function unknown	Complex 1 protein (LYR family);; Complex1_LYR-like	"Succinate dehydrogenase assembly factor 1, mitochondrial {ECO:0000303|PubMed:19465911} OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: succinate dehydrogenase assembly factor 1, mitochondrial [Ursus maritimus]"
ENSG00000205143(ARID3C)	--	0.0813747	2	0.0395193	1	0.0384724	0	0.160536	4	0.0789839	1	0.0800307	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	ARID/BRIGHT DNA binding domain	AT-rich interactive domain-containing protein 3C GN=ARID3C OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: AT-rich interactive domain-containing protein 3C isoform X1 [Galeopterus variegatus]
ENSG00000205155(PSENEN)	--	93.12368	1469	94.39938	1387	93.66608	1464	106.82188	1595	95.13684	1428	105.7172	1655	0.981763539	0.087801623	normal	0.982842203	0.02057952	normal	0.973370626	0.168460461	normal	0.683169758	0.093787366	normal	--	--	--	K06170|2.45074e-67|bacu:103017462|PSENEN; presenilin enhancer gamma secretase subunit; K06170 presenilin enhancer 2 (A)	Notch signaling pathway (ko04330);; Alzheimer's disease (ko05010)	[S]	Function unknown	Presenilin enhancer-2 subunit of gamma secretase	Gamma-secretase subunit PEN-2 GN=PSENEN OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: gamma-secretase subunit PEN-2 isoform X1 [Galeopterus variegatus]
ENSG00000205189(ZBTB10)	--	4.239022673	430	3.38845181	388	4.092576015	425	3.068009226	329	3.11338975	318	3.601032774	372	0.715227454	-0.415378737	normal	0.889123181	-0.307131682	normal	0.94646307	-0.199691558	normal	0.198275848	-0.307427274	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K10497|0|hsa:65986|ZBTB10, RINZF; zinc finger and BTB domain containing 10; K10497 zinc finger and BTB domain-containing protein 10 (A)"	--	[R]	General function prediction only	BTB/POZ domain;; Zinc-finger double domain	Zinc finger and BTB domain-containing protein 10 GN=ZBTB10 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 10 isoform 1 [Odobenus rosmarus divergens]
ENSG00000205208(C4orf46)	--	10.20361864	429	9.521689187	397	8.849548086	363	11.255144	476	10.80993863	454	8.935498284	376	0.963861385	0.118747814	normal	0.953435128	0.171515426	normal	0.968386692	0.04229852	normal	0.709106598	0.113342777	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C4orf46 GN=C4orf46 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C4orf46 homolog [Mustela putorius furo] 
ENSG00000205209(SCGB2B2)	--	0.7645166	6	0.150031	7	0.0840691	3	0	0	0.0822039	3	0.0629223	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Uteroglobin family;; Allergen Fel d I-B chain	Secretoglobin family 2B member 2 (Precursor) GN=SCGB2B2 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: uncharacterized protein LOC101414084 [Dasypus novemcinctus]
ENSG00000205212(CCDC144NL)	--	0.0906695	4	0.176796	8	0.177529	7	0.0889888	4	0.0438836	1	0.0672907	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative coiled-coil domain-containing protein 144 N-terminal-like GN=CCDC144NL OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	--
ENSG00000205213(LGR4)	--	68.5559	5045	78.2543	5772	65.40693	4758	48.34634	3590	47.77927	3528	56.86514	4209	0.325143328	-0.521513388	normal	0.003097884	-0.731399559	normal	0.985459424	-0.185106608	normal	0.00138878	-0.480452629	normal	[S]	Function unknown	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: protein binding (GO:0005515);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04309|0|hsa:55366|LGR4, BNMD17, GPR48; leucine-rich repeat containing G protein-coupled receptor 4; K04309 leucine-rich repeat-containing G protein-coupled receptor 4 (A)"	--	[T]	Signal transduction mechanisms	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine rich repeats (6 copies);; 7 transmembrane receptor (rhodopsin family);; Leucine rich repeat;; Leucine-rich repeat;; Leucine Rich repeat;; Leucine rich repeat N-terminal domain	Leucine-rich repeat-containing G-protein coupled receptor 4 (Precursor) GN=LGR4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"PREDICTED: leucine-rich repeat-containing G-protein coupled receptor 4, partial [Galeopterus variegatus]"
ENSG00000205220(PSMB10)	--	7.843532089	164	8.381663962	178	8.82284887	189	10.58770248	224	11.43380256	239	13.06390283	276	0.80873663	0.415627463	normal	0.819032527	0.400759054	normal	0.479337082	0.534431657	normal	0.106596757	0.456465988	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02733|0|ptr:743176|PSMB10; proteasome (prosome, macropain) subunit, beta type, 10; K02733 20S proteasome subunit beta 10 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit;; Proteasome beta subunits C terminal	Proteasome subunit beta type-10 (Precursor) GN=PSMB10 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-10 [Galeopterus variegatus]
ENSG00000205238(SPDYE2)	--	0.178656	4	0	0	0.127544	2	0.0437198	1	0.130074	2	0.131953	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cell cycle regulatory protein	Speedy protein E2 GN=SPDYE2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: speedy protein E4-like [Ursus maritimus]
ENSG00000205250(E2F4)	--	27.37170112	1158	25.2021	1015	27.42700254	1177	31.80910229	1333	33.00430315	1384	27.92650126	1183	0.968952826	0.171996445	normal	0.658408736	0.425392924	normal	0.981493599	-0.000954466	normal	0.296611368	0.197996032	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: transcription factor complex (GO:0005667);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: protein dimerization activity (GO:0046983);; "	"K04682|0|hsa:1874|E2F4, E2F-4; E2F transcription factor 4, p107/p130-binding; K04682 transcription factor E2F4/5 (A)"	Cell cycle (ko04110);; TGF-beta signaling pathway (ko04350)	[K]	Transcription	E2F/DP family winged-helix DNA-binding domain	Transcription factor E2F4 GN=E2F4 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: transcription factor E2F4 [Eptesicus fuscus]
ENSG00000205268(PDE7A)	--	9.08563	513	9.507072387	542	7.746407	425	7.589845003	431	9.269750412	522	8.99840063	504	0.906914214	-0.281183023	normal	0.969128538	-0.075455054	normal	0.93333669	0.236894514	normal	0.900535826	-0.043649951	normal	--	--	"Molecular Function: 3',5'-cyclic-nucleotide phosphodiesterase activity (GO:0004114);; Biological Process: signal transduction (GO:0007165);; "	"K18436|0|ptr:464213|PDE7A; phosphodiesterase 7A; K18436 high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7 [EC:3.1.4.53] (A)"	Purine metabolism (ko00230);; Morphine addiction (ko05032)	[T]	Signal transduction mechanisms	3'5'-cyclic nucleotide phosphodiesterase	"High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A GN=PDE7A OS=Homo sapiens (Human) PE=1 SV=2"	T	Signal transduction mechanisms	"PREDICTED: high affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A isoform X2 [Oryctolagus cuniculus]"
ENSG00000205269(TMEM170B)	--	4.26776162	487	5.081042446	576	4.862431	538	2.618991542	305	2.828937022	325	3.171272951	362	0.021711803	-0.703114034	normal	0.000844082	-0.844063238	normal	0.165746908	-0.57791426	normal	0.000132053	-0.711245233	normal	--	--	--	--	--	--	--	Putative transmembrane protein 170	Transmembrane protein 170B GN=TMEM170B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 170B [Orycteropus afer afer]
ENSG00000205277(MUC12)	--	1.445144592	22	1.695255155	38	2.429841325	55	2.844911738	36	1.815605845	40	0.248661114	18	0.949471592	0.644200089	normal	0.980642152	0.050610813	normal	0.01770675	-1.542040836	normal	0.748610372	-0.312555473	normal	--	--	--	--	--	--	--	SEA domain	Mucin-12 (Precursor) GN=MUC12 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: mucin-12-like [Oryctolagus cuniculus]
ENSG00000205302(SNX2)	--	22.18649651	949	22.54943225	972	23.19767085	960	19.88974656	864	24.26596424	1004	23.50193965	994	0.964967287	-0.16592735	normal	0.978705482	0.025265815	normal	0.978690042	0.041855205	normal	0.917992512	-0.030281089	normal	[UR]	"Intracellular trafficking, secretion, and vesicular transport;; General function prediction only"	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: phosphatidylinositol binding (GO:0035091);; 	K17917|0|ggo:101140491|SNX2; sorting nexin-2; K17917 sorting nexin-1/2 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	"Vps5 C terminal like;; Sorting nexin, N-terminal domain;; PX domain"	Sorting nexin-2 GN=SNX2 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: sorting nexin-2 [Sorex araneus]
ENSG00000205309(NT5M)	--	8.67407925	240	5.822916547	167	7.6888026	220	3.980576663	111	3.652187	104	3.109737354	95	5.94E-05	-1.132372099	down	0.264161232	-0.696619632	normal	2.68E-05	-1.206800362	down	0.000163319	-1.037635559	down	--	--	Molecular Function: 5'-nucleotidase activity (GO:0008253);; Biological Process: deoxyribonucleotide catabolic process (GO:0009264);; 	"K01081|1.41695e-144|pon:100431715|NT5M; 5',3'-nucleotidase, mitochondrial; K01081 5'-nucleotidase [EC:3.1.3.5] (A)"	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; Nicotinate and nicotinamide metabolism (ko00760)	--	--	"5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)"	"5'(3')-deoxyribonucleotidase, mitochondrial (Precursor) GN=NT5M OS=Homo sapiens (Human) PE=1 SV=1"	F	Nucleotide transport and metabolism	"PREDICTED: 5'(3')-deoxyribonucleotidase, mitochondrial, partial [Mustela putorius furo]"
ENSG00000205336(ADGRG1)	--	23.17260764	1512	22.11396854	1380	25.95560771	1390	34.51317481	2031	52.31035709	3001	31.56993535	2096	0.765426783	0.394552837	normal	1.03E-08	1.09851232	up	0.082517442	0.583741666	normal	0.018906418	0.71425711	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08450|0|hsa:9289|GPR56, BFPP, BPPR, TM7LN4, TM7XN1, ADGRG1; G protein-coupled receptor 56; K08450 G protein-coupled receptor 56 (A)"	--	[T]	Signal transduction mechanisms	7 transmembrane receptor (Secretin family);; Latrophilin/CL-1-like GPS domain	GPR56 C-terminal fragment (Precursor) GN=GPR56 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: G-protein coupled receptor 56 [Galeopterus variegatus] 
ENSG00000205339(IPO7)	--	87.46960172	8273	89.03418861	8459	87.74989127	8444	117.110903	9030	85.57503324	8366	149.979781	8032	0.994903862	0.095466169	normal	0.995386607	-0.037368964	normal	0.994949507	-0.080443978	normal	0.985893701	-0.007173184	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: intracellular protein transport (GO:0006886);; Molecular Function: Ran GTPase binding (GO:0008536);; 	--	--	[YU]	"Nuclear structure;; Intracellular trafficking, secretion, and vesicular transport"	Importin-beta N-terminal domain;; Cse1	Importin-7 GN=IPO7 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	importin-7 [Bos taurus] 
ENSG00000205352(PRR13)	--	177.6452436	2589	174.357697	2624	189.0238734	2686	218.4972692	3106	189.311483	2770	184.5112655	2774	0.970266537	0.231704929	normal	0.988417708	0.056659915	normal	0.989203619	0.038195879	normal	0.612950655	0.109515566	normal	--	--	--	--	--	--	--	--	Proline-rich protein 13 GN=PRR13 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein diaphanous homolog 2-like isoform X1 [Myotis brandtii]
ENSG00000205356(TECPR1)	--	4.579755972	517	2.84305206	407	4.262482987	531	5.108365683	507	4.33545964	570	4.134217894	532	0.970420611	-0.058834228	normal	0.552205223	0.46304649	normal	0.972451196	-0.005561234	normal	0.652212058	0.12445212	normal	--	--	--	K17988|0|hsa:25851|TECPR1; tectonin beta-propeller repeat containing 1; K17988 tectonin beta-propeller repeat-containing protein 1 (A)	--	[R]	General function prediction only	Propeller;; Integral peroxisomal membrane peroxin	Tectonin beta-propeller repeat-containing protein 1 GN=TECPR1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tectonin beta-propeller repeat-containing protein 1 [Tupaia chinensis]
ENSG00000205362(MT1A)	--	10.0251	16	19.221	31	25.11	42	26.7606	49	22.2014	36	13.4291	23	0.058589163	1.497953624	normal	0.980458478	0.18588183	normal	0.853186464	-0.835809313	normal	0.793203414	0.256771268	normal	--	--	--	--	--	--	--	Metallothionein	--	--	--	hypothetical protein CB1_001402132 [Camelus ferus]
ENSG00000205363(C15orf59)	--	0.84109	30	0.483238434	23	0.376867226	16	0.263194865	11	0.5224752	17	0.4463723	18	0.603241462	-1.359082232	normal	0.981952415	-0.42491246	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4589)	UPF0583 protein C15orf59 GN=C15orf59 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0583 protein C15orf59 homolog [Felis catus]
ENSG00000205403(CFI)	--	0.0283785	1	0	0	0	0	0.910670169	21	1.370916358	54	2.461528762	77	0.018698519	3.130949278	normal	7.73E-12	5.187618658	up	0	5.694053179	up	2.22E-05	7.228111863	up	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Molecular Function: scavenger receptor activity (GO:0005044);; Molecular Function: protein binding (GO:0005515);; Biological Process: proteolysis (GO:0006508);; Cellular Component: membrane (GO:0016020);; 	"K01333|0|ptr:471271|CFI, IF; complement factor I; K01333 complement factor I [EC:3.4.21.45] (A)"	Complement and coagulation cascades (ko04610);; Staphylococcus aureus infection (ko05150)	[E]	Amino acid transport and metabolism	Trypsin;; Low-density lipoprotein receptor domain class A;; Scavenger receptor cysteine-rich domain	Complement factor I light chain (Precursor) GN=CFI OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	PREDICTED: complement factor I [Loxodonta africana]
ENSG00000205413(SAMD9)	--	2.728304699	376	2.08914022	283	3.089300936	412	3.705855029	512	3.176466648	431	3.241956916	447	0.706055621	0.413127308	normal	0.209385142	0.582918	normal	0.964718424	0.108955008	normal	0.110918233	0.354929321	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	SAM domain (Sterile alpha motif);; SAM domain (Sterile alpha motif)	Sterile alpha motif domain-containing protein 9 GN=SAMD9 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: sterile alpha motif domain-containing protein 9 [Galeopterus variegatus]
ENSG00000205423(CNEP1R1)	--	12.89935152	346	15.76853912	426	14.918358	409	15.13461094	411	15.42506509	419	16.09728313	444	0.94051067	0.216650584	normal	0.968482193	-0.045168063	normal	0.96456413	0.10977772	normal	0.788536404	0.08846111	normal	--	--	Biological Process: positive regulation of protein dephosphorylation (GO:0035307);; Cellular Component: Nem1-Spo7 phosphatase complex (GO:0071595);; 	--	--	[S]	Function unknown	Transmembrane protein 188	Nuclear envelope phosphatase-regulatory subunit 1 GN=CNEP1R1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nuclear envelope phosphatase-regulatory subunit 1 isoform X1 [Camelus ferus]
ENSG00000205436(EXOC3L4)	--	1.1963988	60	0.941048115	53	0.902146	53	0.533826468	28	0.849887137	43	0.657933	39	0.264832935	-1.088589639	normal	0.965983205	-0.313143198	normal	0.953498524	-0.436243582	normal	0.267400513	-0.613905702	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: exocytosis (GO:0006887);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec6	Exocyst complex component 3-like protein 4 GN=EXOC3L4 OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 3-like protein 4 [Galeopterus variegatus] 
ENSG00000205456(TP53TG3D)	--	0.579337168	19	0.5866017	15	0.325855383	9	0.50306307	15	0.110353381	3	0.531586142	15	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TP53-target gene 3 protein GN=TP53TG3D OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000205464(ATP6AP1L)	--	0.5103903	8	0.558174	18	0.35229633	14	0.2265397	5	0.3497312	14	0.219395376	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Cellular Component: proton-transporting V-type ATPase, V1 domain (GO:0033180);; Molecular Function: proton-transporting ATP synthase activity, rotational mechanism (GO:0046933);; Molecular Function: proton-transporting ATPase activity, rotational mechanism (GO:0046961);; "	--	--	[C]	Energy production and conversion	--	V-type proton ATPase subunit S1-like protein GN=ATP6AP1L OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit S1-like protein isoform 5 [Dasypus novemcinctus]
ENSG00000205476(CCDC85C)	--	21.50464653	2221	16.31115724	2016	23.51060507	2420	26.46684763	2639	21.98749331	2406	16.820958	2034	0.97079352	0.217811337	normal	0.964612214	0.233553903	normal	0.95510049	-0.258802166	normal	0.790313523	0.066982451	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved proteins (DUF2216)	Coiled-coil domain-containing protein 85C GN=CCDC85C OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: coiled-coil domain-containing protein 85C, partial [Galeopterus variegatus]"
ENSG00000205502(C2CD4B)	--	0	0	0	0	0	0	0.0529898	1	0	0	0.05243	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C2 calcium-dependent domain-containing protein 4B GN=C2CD4B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: C2 calcium-dependent domain-containing protein 4A isoform X1 [Myotis lucifugus] 
ENSG00000205517(RGL3)	--	2.2084672	118	1.627705347	84	2.140695915	89	0.828354312	43	1.112063726	56	1.889223768	64	7.56E-05	-1.454493901	down	0.813605469	-0.593216907	normal	0.894903151	-0.474474605	normal	0.03360291	-0.856276208	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: signal transduction (GO:0007165);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17639|0|hsa:57139|RGL3; ral guanine nucleotide dissociation stimulator-like 3; K17639 ral guanine nucleotide dissociation stimulator-like 3 (A)	--	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; Ras association (RalGDS/AF-6) domain	Ral guanine nucleotide dissociation stimulator-like 3 GN=RGL3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ral guanine nucleotide dissociation stimulator-like 3 [Camelus dromedarius]
ENSG00000205531(NAP1L4)	--	53.5308304	2563	57.0744128	2733	59.29133271	2834	64.2982859	3078	57.26566042	2744	52.79004928	2444	0.969663442	0.233199789	normal	0.98919263	-0.015622909	normal	0.971418455	-0.221759362	normal	0.996314771	0.002152792	normal	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	K11282|0|ptr:450961|NAP1L4; nucleosome assembly protein 1-like 4; K11282 nucleosome assembly protein 1-like 4 (A)	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	Nucleosome assembly protein (NAP)	Nucleosome assembly protein 1-like 4 GN=NAP1L4 OS=Homo sapiens (Human) PE=1 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: nucleosome assembly protein 1-like 4 isoform X1 [Tupaia chinensis] 
ENSG00000205542(TMSB4X)	--	3522.640698	26497	3768.266079	28308	3340.358769	25216	4942.37073	38998	5025.988506	37833	4209.596818	32182	0.657298444	0.526713533	normal	0.963237111	0.396990396	normal	0.980772213	0.343604821	normal	0.029156804	0.4241616	normal	--	--	--	"K05764|2.08503e-22|oas:101106384|thymosin beta-4-like; K05764 thymosin, beta 4 (A)"	Regulation of actin cytoskeleton (ko04810)	[N]	Cell motility	--	Hematopoietic system regulatory peptide GN=TMSB4X OS=Homo sapiens (Human) PE=1 SV=2	N	Cell motility	PREDICTED: thymosin beta-4-like [Ovis aries]
ENSG00000205544(TMEM256)	--	237.226108	735	191.56393	618	191.09756	631	198.91071	674	221.716621	689	171.910257	557	0.963227523	-0.155488346	normal	0.965158693	0.135157246	normal	0.953612426	-0.18777479	normal	0.815425051	-0.069077793	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF423)	Transmembrane protein 256 (Precursor) GN=TMEM256 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 256 isoform X1 [Myotis brandtii] 
ENSG00000205571(SMN2)	--	2.794116628	65	2.545458595	62	4.569074363	108	3.184060545	74	3.367177763	78	2.036234255	50	0.971355272	0.152865304	normal	0.954446002	0.303174379	normal	0.017358492	-1.096216711	normal	0.715386016	-0.239436139	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Cellular Component: nucleus (GO:0005634);; Cellular Component: cytoplasm (GO:0005737);; Biological Process: mRNA processing (GO:0006397);; 	K13129|3.61946e-118|pps:100984482|SMN1; survival motor neuron protein; K13129 survival motor neuron protein (A)	RNA transport (ko03013)	[A]	RNA processing and modification	Survival motor neuron protein (SMN)	Survival motor neuron protein GN=SMN2 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: survival of motor neuron protein-like isoform X1 [Panthera tigris altaica] 
ENSG00000205572(SERF1B)	--	0.488582437	15	0.768048104	25	0.657408299	21	0.40920975	11	0.487005157	14	0.665050097	14	--	--	--	0.953886442	-0.793020907	normal	0.981361614	-0.544909994	normal	--	--	--	--	--	--	--	--	[R]	General function prediction only	4F5 protein family	Small EDRK-rich factor 1 GN=SERF1B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: small EDRK-rich factor 1-like [Elephantulus edwardii]
ENSG00000205581(HMGN1)	--	100.1294824	2179	94.84520934	2142	99.23537175	2212	146.345408	3254	131.3165855	2866	133.348581	2918	0.182026089	0.547398052	normal	0.794845419	0.398409631	normal	0.80465156	0.391103539	normal	0.002563724	0.446742064	normal	--	--	Cellular Component: chromatin (GO:0000785);; Cellular Component: nucleus (GO:0005634);; Molecular Function: nucleosomal DNA binding (GO:0031492);; 	K11299|1.05089e-32|pon:100432372|HMGN1; high mobility group nucleosome binding domain 1; K11299 high-mobility group nucleosome-binding domain-containing protein 1 (A)	Herpes simplex infection (ko05168)	--	--	HMG14 and HMG17	Non-histone chromosomal protein HMG-14 GN=HMGN1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: non-histone chromosomal protein HMG-14 isoform 1 [Orcinus orca] 
ENSG00000205593(DENND6B)	--	1.792135	102	1.010455459	85	1.166515142	79	0.992021	69	1.835469	112	1.693638318	104	0.765479249	-0.583965414	normal	0.9181659	0.370774949	normal	0.921479861	0.381975979	normal	0.908958444	0.07935747	normal	--	--	--	--	--	[S]	Function unknown	Stabilization of polarity axis;; DENN (AEX-3) domain;; Transport protein Avl9	Protein DENND6B GN=DENND6B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein DENND6B isoform X3 [Canis lupus familiaris]
ENSG00000205609(EIF3CL)	--	0.0523989	4	0.051646032	4	0.0882874	6	0.09138835	7	0.090184213	6	0.078156414	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: translation initiation factor activity (GO:0003743);; Molecular Function: protein binding (GO:0005515);; Cellular Component: eukaryotic translation initiation factor 3 complex (GO:0005852);; Biological Process: translational initiation (GO:0006413);; Molecular Function: translation initiation factor binding (GO:0031369);; 	"K03252|0|hsa:728689|EIF3CL; eukaryotic translation initiation factor 3, subunit C-like; K03252 translation initiation factor 3 subunit C (A)"	RNA transport (ko03013)	[J]	"Translation, ribosomal structure and biogenesis"	Eukaryotic translation initiation factor 3 subunit 8 N-terminus;; PCI domain	Eukaryotic translation initiation factor 3 subunit C-like protein GN=EIF3CL OS=Homo sapiens (Human) PE=3 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 3 subunit C-like isoform 1 [Odobenus rosmarus divergens] 
ENSG00000205629(LCMT1)	--	17.985411	408	18.987722	434	19.54528231	420	18.83127614	448	17.82806494	401	22.15459	488	0.965128884	0.103724489	normal	0.960138153	-0.135029705	normal	0.944765747	0.207506625	normal	0.857820638	0.062285167	normal	--	--	Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: methylation (GO:0032259);; 	K18203|0|ggo:101148281|leucine carboxyl methyltransferase 1-like isoform 1; K18203 [phosphatase 2A protein]-leucine-carboxy methyltransferase [EC:2.1.1.233] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Leucine carboxyl methyltransferase	Leucine carboxyl methyltransferase 1 GN=LCMT1 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: leucine carboxyl methyltransferase 1 isoform X1 [Orycteropus afer afer]
ENSG00000205639(MFSD2B)	--	0.0444694	2	0.0436863	2	0.128574	5	0.04462441	2	0.089110029	1	0.0655465	3	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	--	--	--	[G]	Carbohydrate transport and metabolism	MFS/sugar transport protein	Major facilitator superfamily domain-containing protein 2B GN=MFSD2B OS=Homo sapiens (Human) PE=2 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: major facilitator superfamily domain-containing protein 2B [Tupaia chinensis]
ENSG00000205643(CDPF1)	--	5.973660215	177	4.6333274	131	5.787927871	183	4.370344061	140	3.34136	106	4.201800426	126	0.884554746	-0.365577197	normal	0.925510032	-0.322778188	normal	0.617774469	-0.54128891	normal	0.231487522	-0.421682253	normal	--	--	--	--	--	[S]	Function unknown	Cysteine-rich domain	Cysteine-rich DPF motif domain-containing protein 1 GN=CDPF1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: cysteine-rich DPF motif domain-containing protein 1 isoform X1 [Equus caballus]
ENSG00000205659(LIN52)	--	4.334904232	207	4.13856339	197	4.677590001	197	3.76598525	179	3.783908979	179	4.2202037	201	0.939209621	-0.238596886	normal	0.955572894	-0.158386456	normal	0.966859764	0.020552236	normal	0.76783972	-0.125404125	normal	--	--	"Biological Process: transcription, DNA-templated (GO:0006351);; Biological Process: cell cycle (GO:0007049);; Cellular Component: DRM complex (GO:0070176);; "	--	--	[S]	Function unknown	Retinal tissue protein	Protein lin-52 homolog GN=LIN52 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein lin-52 homolog [Vicugna pacos]
ENSG00000205669(ACOT6)	--	0.0826283	1	0	0	0	0	0	0	0.080222	0	0.0813785	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K11993|1.39081e-152|hsa:641372|ACOT6, C14orf42, c14_5530; acyl-CoA thioesterase 6 (EC:3.1.2.2); K11993 acyl-CoA thioesterase 6 [EC:3.1.2.-] (A)"	--	--	--	BAAT / Acyl-CoA thioester hydrolase C terminal;; Dienelactone hydrolase family;; Serine hydrolase (FSH1)	Putative acyl-coenzyme A thioesterase 6 GN=ACOT6 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-coenzyme A thioesterase 6-like [Equus caballus]
ENSG00000205683(DPF3)	--	0.037510891	3	0.012443337	1	0	0	0.187141303	15	0.130829394	7	0.086631422	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	N-terminal domain of DPF2/REQ.	Zinc finger protein DPF3 GN=DPF3 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	"PREDICTED: LOW QUALITY PROTEIN: D4, zinc and double PHD fingers, family 3 [Trichechus manatus latirostris]"
ENSG00000205693(MANSC4)	--	0.0730224	1	0	0	0.0728889	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MANEC domain	MANSC domain-containing protein 4 (Precursor) GN=MANSC4 OS=Homo sapiens (Human) PE=3 SV=3	R	General function prediction only	PREDICTED: MANSC domain-containing protein 4 [Trichechus manatus latirostris]
ENSG00000205707(ETFRF1)	--	12.849382	171	9.455039015	126	10.1402	134	11.623054	159	8.680009	115	11.565902	153	0.960971149	-0.134547703	normal	0.961164473	-0.151314613	normal	0.956651904	0.181093297	normal	0.959760283	-0.03502344	normal	--	--	--	--	--	--	--	Complex 1 protein (LYR family);; Complex1_LYR-like;; Complex1_LYR-like	LYR motif-containing protein 5 GN=LYRM5 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LYR motif-containing protein 5 isoform X1 [Tupaia chinensis] 
ENSG00000205710(C17orf107)	--	0.164034	10	0.1640778	9	0.2999246	17	0.2580906	12	0.12684	7	0.27475	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C17orf107 GN=C17orf107 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C17orf107 homolog [Galeopterus variegatus]
ENSG00000205726(ITSN1)	--	7.678676649	864	9.104718691	981	10.0612868	1017	7.84399506	873	7.711754466	792	8.271778669	880	0.977808248	-0.015853876	normal	0.867381292	-0.329612537	normal	0.952029308	-0.216688975	normal	0.349177597	-0.190415407	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Variant SH3 domain;; SH3 domain;; Variant SH3 domain;; RhoGEF domain;; Cytoskeletal-regulatory complex EF hand;; C2 domain;; EF hand;; EF-hand domain pair;; EF-hand domain	Intersectin-1 GN=ITSN1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: intersectin-1 [Tupaia chinensis]
ENSG00000205730(ITPRIPL2)	--	10.696549	1200	13.56739	1576	11.723267	1228	11.273704	1244	12.271721	1337	14.024099	1559	0.981677899	0.021093291	normal	0.944221799	-0.258425043	normal	0.87213088	0.335651239	normal	0.950458395	0.027404621	normal	--	--	--	--	--	--	--	Mab-21 protein	"Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 (Precursor) GN=ITPRIPL2 OS=Homo sapiens (Human) PE=1 SV=1"	T	Signal transduction mechanisms	"PREDICTED: inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 [Galeopterus variegatus]"
ENSG00000205744(DENND1C)	--	0.506229	21	0.266975	11	0.357318583	15	1.06982	44	1.467713002	40	0.786747	33	0.718142724	0.985499747	normal	0.051393373	1.710451729	normal	0.812313753	1.055839999	normal	0.023419946	1.293768119	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; uDENN domain;; dDENN domain	DENN domain-containing protein 1C GN=DENND1C OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 1C [Galeopterus variegatus]
ENSG00000205755(CRLF2)	--	0.618822286	20	0.520421141	16	0.945075	30	0.778303397	24	0.715496209	16	0.807023807	25	0.986837121	0.21697238	normal	--	--	--	0.982580345	-0.25710934	normal	0.986272296	-0.042250434	normal	--	--	--	K05078|0|nle:100582238|CRLF2; cytokine receptor-like factor 2; K05078 thymic stromal-derived lymphopoietin receptor (A)	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	--	Cytokine receptor-like factor 2 (Precursor) GN=CRLF2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: cytokine receptor-like factor 2 [Galeopterus variegatus]
ENSG00000205758(CRYZL1)	--	9.640399	239	9.981801	256	9.254462	209	9.232256	227	9.8216348	242	8.784772	220	0.962471698	-0.104461391	normal	0.961607084	-0.101943813	normal	0.965343256	0.065248926	normal	0.909432783	-0.052617834	normal	[CR]	Energy production and conversion;; General function prediction only	--	"K00540|0|hsa:9946|CRYZL1, 4P11, QOH-1; crystallin, zeta (quinone reductase)-like 1 (A)"	--	[CR]	Energy production and conversion;; General function prediction only	Zinc-binding dehydrogenase;; Alcohol dehydrogenase GroES-like domain	Quinone oxidoreductase-like protein 1 GN=CRYZL1 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	PREDICTED: quinone oxidoreductase-like protein 1 isoform 1 [Dasypus novemcinctus]
ENSG00000205765(C5orf51)	--	9.982993608	663	12.82944575	838	11.296227	724	13.009487	853	11.51099241	764	14.64240949	975	0.85721188	0.332024779	normal	0.964880273	-0.154512001	normal	0.654156911	0.420361768	normal	0.385517432	0.199307355	normal	--	--	--	--	--	--	--	--	UPF0600 protein C5orf51 GN=C5orf51 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0600 protein C5orf51 homolog [Tupaia chinensis]
ENSG00000205795(CYS1)	--	3.3081	158	2.09254	103	2.62156	130	0.94027	45	2.05955	98	0.892337	43	6.43E-09	-1.80762727	down	0.967501507	-0.09183472	normal	5.40E-06	-1.571024955	down	0.018134175	-1.092633972	normal	--	--	--	--	--	--	--	--	Cystin-1 GN=CYS1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	Cystin-1 [Pteropus alecto]
ENSG00000205808(PLPP6)	--	12.3776	562	10.1054	462	10.8324	491	9.40294	430	8.48742	384	10.9651	499	0.688513497	-0.415761829	normal	0.903002754	-0.287180318	normal	0.971642962	0.014979583	normal	0.340488015	-0.227278182	normal	--	--	--	--	--	[S]	Function unknown	PAP2 superfamily	Presqualene diphosphate phosphatase GN=PPAPDC2 OS=Homo sapiens (Human) PE=1 SV=3	I	Lipid transport and metabolism	PREDICTED: presqualene diphosphate phosphatase [Orcinus orca] 
ENSG00000205832(C16orf96)	--	0.0234426	2	0	0	0	0	0.0118237	1	0.0342933	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C16orf96 {ECO:0000305} OS=Homo sapiens (Human) PE=4 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C16orf96 homolog [Loxodonta africana]
ENSG00000205838(TTC23L)	--	0.057966454	1	0.174158026	4	0	0	0	0	0.072226142	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Tetratricopeptide repeat	Tetratricopeptide repeat protein 23-like GN=TTC23L OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: tetratricopeptide repeat protein 23-like, partial [Galeopterus variegatus]"
ENSG00000205853(RFPL3S)	--	0.923197641	30	1.260736186	29	1.52405639	25	0.395166536	8	0.808119903	13	0.86167298	36	0.191601191	-1.753092351	normal	0.835825052	-1.091894794	normal	0.966549577	0.492814247	normal	0.543659476	-0.576631239	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	Putative protein RFPL3S GN=RFPL3S OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: ret finger protein-like 3-like [Tupaia chinensis]
ENSG00000205861(PCOTH)	--	0.0948554	1	0.285043424	3	0.569754	4	0.447584	3	0.809096	5	0.652951	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Complement C1q and tumor necrosis factor-related protein 9B (Precursor) GN=C1QTNF9B OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: complement C1q and tumor necrosis factor-related protein 9A isoform 1 [Ceratotherium simum simum] 
ENSG00000205863(C1QTNF9B)	--	0	0	0	0	0.054790728	1	0	0	0	0	0.0381603	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	C1q domain;; Collagen triple helix repeat (20 copies)	Complement C1q and tumor necrosis factor-related protein 9B (Precursor) GN=C1QTNF9B OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: complement C1q and tumor necrosis factor-related protein 9A [Mustela putorius furo] 
ENSG00000205864(KRTAP5-6)	--	0	0	0	0	0	0	0	0	0	0	0.223783	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC102977792 [Physeter catodon]
ENSG00000205867(KRTAP5-2)	--	0.147992	2	0	0	0.212278	2	0.146443	2	0.364606	4	0.220744	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: keratin filament (GO:0045095);; 	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized transmembrane protein DDB_G0289901-like [Galeopterus variegatus]
ENSG00000205869(KRTAP5-1)	--	0.180241	2	0.0831249	1	0.168252	1	0.177657	2	0.358267	3	0.272081	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC102977792 [Physeter catodon]
ENSG00000205903(ZNF316)	--	11.05723284	1030	11.075637	1108	8.915393934	872	9.806345	949	11.390628	1068	11.95715	1128	0.969448522	-0.148765325	normal	0.978028698	-0.074369395	normal	0.812629852	0.362521348	normal	0.884101377	0.042279938	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:100131017|ZNF316, MZF-3; zinc finger protein 316; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc-finger of C2H2 type"	Zinc finger protein 316 GN=ZNF316 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: uncharacterized protein LOC101402837 [Ceratotherium simum simum]
ENSG00000205922(ONECUT3)	--	0	0	0.00583019	1	0.0113853	1	0.00594273	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	CUT domain;; Homeobox domain	One cut domain family member 3 GN=ONECUT3 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: one cut domain family member 3 [Canis lupus familiaris]
ENSG00000205923(CEMP1)	--	7.275753	165	10.43665	219	8.71149	181	5.265873	111	5.437126	124	8.24991	197	0.523826082	-0.595925068	normal	0.023197177	-0.834254436	normal	0.962224143	0.113009205	normal	0.334017149	-0.406848705	normal	--	--	--	--	--	--	--	--	Cementoblastoma-derived protein 1 GN=CEMP1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000205937(RNPS1)	--	78.2808728	2957	73.9850449	2698	77.15789714	2897	88.3720321	3260	103.556328	3705	72.98433152	2798	0.987854639	0.109851085	normal	0.705801085	0.435947325	normal	0.989115361	-0.058424129	normal	0.392412726	0.16961038	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K14325|3.8996e-58|mcc:695816|uncharacterized LOC695816; K14325 RNA-binding protein with serine-rich domain 1 (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	RNA-binding protein with serine-rich domain 1 GN=RNPS1 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein with serine-rich domain 1 [Chrysochloris asiatica]
ENSG00000205978(NYNRIN)	--	0.231615	39	0.116537	20	0.103435	17	0.155554	26	0.388745	65	0.112058	19	0.950174402	-0.587264609	normal	0.003180818	1.608030147	up	--	--	--	0.726728379	0.511515747	normal	[L]	"Replication, recombination and repair"	--	--	--	[S]	Function unknown	Zc3h12a-like Ribonuclease NYN domain	Protein NYNRIN GN=NYNRIN OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein NYNRIN [Galeopterus variegatus]
ENSG00000205981(DNAJC19)	--	11.4821679	210	11.31315441	204	12.39666525	217	11.2208747	213	11.34140548	203	12.16704839	231	0.966934684	-0.010293385	normal	0.965518165	-0.028305634	normal	0.964369546	0.081356765	normal	0.984445003	0.015243371	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	"K09539|2.89415e-79|ptr:460868|DNAJC19; DnaJ (Hsp40) homolog, subfamily C, member 19; K09539 DnaJ homolog subfamily C member 19 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	DnaJ domain	Mitochondrial import inner membrane translocase subunit TIM14 GN=DNAJC19 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: mitochondrial import inner membrane translocase subunit TIM14 [Mustela putorius furo] 
ENSG00000206052(DOK6)	--	0.0804966	12	0.0940921	14	0.3297235	4	0.3067627	7	0.3029767	11	0.0332406	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: insulin receptor binding (GO:0005158);; 	--	--	[T]	Signal transduction mechanisms	PTB domain (IRS-1 type);; PH domain	Docking protein 6 GN=DOK6 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: docking protein 6 isoform X1 [Myotis lucifugus] 
ENSG00000206053(HN1L)	--	66.41147659	3909	65.4635909	4049	68.68897984	4089	89.89026453	5442	77.2928515	4646	72.44285451	4312	0.695420833	0.446355828	normal	0.985834988	0.176935223	normal	0.991680396	0.068293075	normal	0.185117982	0.235508559	normal	--	--	--	--	--	--	--	--	Hematological and neurological expressed 1-like protein GN=HN1L OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: hematological and neurological expressed 1-like protein [Equus caballus]
ENSG00000206072(SERPINB11)	--	0	0	0	0	0	0	0	0	0	0	0.075693991	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K13966|0|ggo:101140378|SERPINB11; serpin B11; K13966 serpin B11/12 (A)	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B11 GN=SERPINB11 OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: serpin B11 isoform X1 [Galeopterus variegatus]
ENSG00000206073(SERPINB4)	--	0	0	0	0	0	0	0.415233151	9	0.329061117	9	0.30242734	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K13963|0|hsa:6318|SERPINB4, LEUPIN, PI11, SCCA-2, SCCA1, SCCA2; serpin peptidase inhibitor, clade B (ovalbumin), member 4; K13963 serpin B (A)"	Amoebiasis (ko05146)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B4 GN=SERPINB4 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: serpin B4-like [Galeopterus variegatus]
ENSG00000206075(SERPINB5)	--	0.0204691	1	0	0	0.0920747	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K10139|0|hsa:5268|SERPINB5, PI5, maspin; serpin peptidase inhibitor, clade B (ovalbumin), member 5; K10139 serpin B5 (A)"	p53 signaling pathway (ko04115);; MicroRNAs in cancer (ko05206)	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin B5 GN=SERPINB5 OS=Homo sapiens (Human) PE=1 SV=2	V	Defense mechanisms	PREDICTED: serpin B5 [Sus scrofa]
ENSG00000206077(ZDHHC11B)	--	0.16531407	5	0.0664699	2	0.272917818	7	0.19632	6	0.192424	5	0.180288654	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K18932|0|hsa:653082|ZDHHC11B, DHHC-11B; zinc finger, DHHC-type containing 11B; K18932 palmitoyltransferase [EC:2.3.1.225] (A)"	--	[R]	General function prediction only	DHHC palmitoyltransferase	Probable palmitoyltransferase ZDHHC11B GN=ZDHHC11B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: probable palmitoyltransferase ZDHHC11 [Equus przewalskii] 
ENSG00000206127(GOLGA8O)	--	0.41781337	21	0.19527824	10	0.44220707	22	0.217133921	11	0.63680923	32	0.216611467	11	0.962137029	-0.874022663	normal	0.352223199	1.521980216	normal	0.952638662	-0.917593066	normal	1	0.007152353	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8O GN=GOLGA8O OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: golgin subfamily A member 2-like [Pteropus alecto]
ENSG00000206140(TMEM191C)-3	--	1.415267	27	1.343761104	23	1.211100171	25	0.670146457	14	0.633976527	12	0.565081767	12	0.929793715	-0.90562601	normal	0.950295282	-0.878800022	normal	0.924998507	-0.979980201	normal	0.148079647	-1.002564002	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000206172(HBA1)	--	0	0	0	0	0	0	0	0	0	0	0.229607454	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: oxygen binding (GO:0019825);; Molecular Function: heme binding (GO:0020037);; 	"K13822|5.58785e-98|ptr:732486|HBA1, HBA2; hemoglobin, alpha 2; K13822 hemoglobin subunit alpha (A)"	African trypanosomiasis (ko05143);; Malaria (ko05144)	[C]	Energy production and conversion	Globin	Hemoglobin subunit alpha GN=HBA2 OS=Homo sapiens (Human) PE=1 SV=2	C	Energy production and conversion	RecName: Full=Hemoglobin subunit alpha; AltName: Full=Alpha-globin; AltName: Full=Hemoglobin alpha chain [Myotis velifer]
ENSG00000206181(ELOA2)	--	0.035935303	2	0	0	0	0	0.0295991	1	0.0287304	0	0.02964464	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Cellular Component: integral component of membrane (GO:0016021);; "	"K15076|0|hsa:51224|TCEB3B, ELOA2, HsT832, TCEB3L; transcription elongation factor B polypeptide 3B (elongin A2); K15076 transcription elongation factor B, polypeptide 3 (A)"	--	[K]	Transcription	RNA polymerase II transcription factor SIII (Elongin) subunit A;; TFIIS helical bundle-like domain	RNA polymerase II transcription factor SIII subunit A2 GN=TCEB3B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	transcription elongation factor B polypeptide 3 [Equus caballus]
ENSG00000206190(ATP10A)	--	1.520184627	154	1.552614829	160	1.915706218	171	4.738829483	457	6.007481846	561	4.042532935	403	6.70E-12	1.529155204	up	1.11E-16	1.778943225	up	2.09E-07	1.221244797	up	8.49E-11	1.529601816	up	[P]	Inorganic ion transport and metabolism	--	"K01530|0|hsa:57194|ATP10A, ATP10C, ATPVA, ATPVC; ATPase, class V, type 10A (EC:3.6.3.1); K01530 phospholipid-translocating ATPase [EC:3.6.3.1] (A)"	--	[R]	General function prediction only	haloacid dehalogenase-like hydrolase;; haloacid dehalogenase-like hydrolase;; E1-E2 ATPase;; Putative hydrolase of sodium-potassium ATPase alpha subunit	Probable phospholipid-transporting ATPase VA GN=ATP10A OS=Homo sapiens (Human) PE=2 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: probable phospholipid-transporting ATPase VA [Canis lupus familiaris]
ENSG00000206199(ANKUB1)	--	0	0	0	0	0	0	0	0	0	0	0.05145984	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeats (many copies);; Ubiquitin family;; Ankyrin repeat	Protein ANKUB1 GN=ANKUB1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: protein ANKUB1 [Ceratotherium simum simum]
ENSG00000206203(TSSK2)	--	0.927323	32	1.07013	37	1.09407	38	1.20299	42	1.15001	39	0.992522	35	0.973037025	0.346911613	normal	0.980953959	0.052434763	normal	0.981592247	-0.121880373	normal	0.928709813	0.094928816	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08811|0|hsa:23617|TSSK2, DGS-G, SPOGA2, STK22B, TSK2; testis-specific serine kinase 2 (EC:2.7.11.1); K08811 testis-specific serine kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Testis-specific serine/threonine-protein kinase 2 GN=TSSK2 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: testis-specific serine/threonine-protein kinase 2 [Canis lupus familiaris]
ENSG00000206260(PRR23A)	--	0.0972031	1	0	0	0	0	0	0	0	0	0.0947727	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF2476)	Proline-rich protein 23A GN=PRR23A OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: proline-rich protein 23A-like [Ceratotherium simum simum]
ENSG00000206262(FOXL2NB)	--	0.29363007	22	0.467389552	34	0.1878861	12	1.250980009	87	1.142154	76	1.062580706	74	1.04E-05	1.881815374	up	0.10031761	1.105345409	normal	1.42E-07	2.474695038	up	3.84E-05	1.778190866	up	--	--	--	--	--	--	--	--	FOXL2 neighbor protein GN=FOXL2NB OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: FOXL2 neighbor protein [Felis catus]
ENSG00000206384(COL6A6)	--	0	0	0.00487967	1	0	0	0.009859787	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06238|0|hsa:131873|COL6A6; collagen, type VI, alpha 6; K06238 collagen, type VI, alpha (A)"	PI3K-Akt signaling pathway (ko04151);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Protein digestion and absorption (ko04974)	[W]	Extracellular structures	von Willebrand factor type A domain;; von Willebrand factor type A domain;; Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; VWA domain containing CoxE-like protein	Collagen alpha-6(VI) chain (Precursor) GN=COL6A6 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-6(VI) chain [Odobenus rosmarus divergens]
ENSG00000206418(RAB12)	--	17.464216	602	18.591325	649	18.501802	642	17.792216	620	19.723975	674	14.846296	515	0.973797066	0.011643184	normal	0.973708762	0.033028035	normal	0.864328335	-0.325434587	normal	0.757636783	-0.087079632	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07907|3.41284e-135|mdo:100012957|RAB12; RAB12, member RAS oncogene family; K07907 Ras-related protein Rab-12 (A)"	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase;; Signal recognition particle receptor beta subunit	Ras-related protein Rab-12 GN=RAB12 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-12 [Monodelphis domestica]
ENSG00000206503(HLA-A)	--	87.43559649	1683	63.03022188	1566	70.34378255	1469	88.68668117	1949	81.466569	1874	86.5014	1825	0.973596972	0.180713249	normal	0.957578361	0.237400379	normal	0.915257706	0.304488874	normal	0.170799444	0.238014074	normal	--	--	Biological Process: immune response (GO:0006955);; Biological Process: antigen processing and presentation (GO:0019882);; 	"K06751|0|pps:100978112|Papa-A; patr class I histocompatibility antigen, A-2 alpha chain-like; K06751 major histocompatibility complex, class I (A)"	Endocytosis (ko04144);; Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Type I diabetes mellitus (ko04940);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203);; Autoimmune thyroid disease (ko05320);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	"Class I Histocompatibility antigen, domains alpha 1 and 2;; Immunoglobulin C1-set domain;; MHC_I C-terminus"	"HLA class I histocompatibility antigen, A-3 alpha chain (Precursor) GN=HLA-A OS=Homo sapiens (Human) PE=1 SV=2"	S	Function unknown	MHC class I antigen [Tupaia belangeri]
ENSG00000206527(HACD2)	--	30.334499	1849	34.92289913	2157	31.13558418	1883	34.354345	2114	33.61736914	2073	35.71370448	2175	0.977895497	0.162271719	normal	0.985425549	-0.078676345	normal	0.971787527	0.199541728	normal	0.691762843	0.090201913	normal	--	--	--	"K10703|3.88291e-163|pon:100172398|PTPLB, HACD2; protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b (EC:4.2.1.134); K10703 very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase [EC:4.2.1.134] (A)"	Fatty acid elongation (ko00062);; Biosynthesis of unsaturated fatty acids (ko01040);; Fatty acid metabolism (ko01212)	[R]	General function prediction only	"Protein tyrosine phosphatase-like protein, PTPLA"	Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 2 GN=PTPLB OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: very-long-chain (3R)-3-hydroxyacyl-[acyl-carrier protein] dehydratase 2 [Bubalus bubalis]
ENSG00000206535(LNP1)	--	1.08578539	42	0.966317	38	0.988673	38	1.10449	43	1.20538	46	0.539475577	21	0.981161321	0.003006379	normal	0.974269287	0.245323763	normal	0.88942263	-0.819442978	normal	0.899556811	-0.124181778	normal	--	--	--	--	--	--	--	Leukemia NUP98 fusion partner 1	Leukemia NUP98 fusion partner 1 GN=LNP1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: leukemia NUP98 fusion partner 1 isoform X1 [Equus caballus]
ENSG00000206538(VGLL3)	--	2.941457	409	2.144939271	320	3.640053	496	6.433917	972	8.690635539	1156	5.838318419	873	1.21E-09	1.214974377	up	0	1.82671955	up	0.000717496	0.805474825	normal	1.03E-08	1.271912975	up	--	--	"Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	Vestigial/Tondu family	Transcription cofactor vestigial-like protein 3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription cofactor vestigial-like protein 3 isoform X1 [Myotis lucifugus]
ENSG00000206549(PRSS50)	--	0.0172024	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	[E]	Amino acid transport and metabolism	Trypsin;; Domain of unknown function (DUF1986)	Probable threonine protease PRSS50 (Precursor) GN=PRSS50 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: probable threonine protease PRSS50 [Galeopterus variegatus]
ENSG00000206557(TRIM71)	--	0.0143975	2	0	0	0	0	0	0	0	0	0.0071285	1	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	"K12035|0|hsa:131405|TRIM71, LIN-41, LIN41; tripartite motif containing 71, E3 ubiquitin protein ligase; K12035 tripartite motif-containing protein 71 [EC:6.3.2.19] (A)"	MicroRNAs in cancer (ko05206)	[O]	"Posttranslational modification, protein turnover, chaperones"	NHL repeat;; Filamin/ABP280 repeat;; B-box zinc finger;; SMP-30/Gluconolaconase/LRE-like region	E3 ubiquitin-protein ligase TRIM71 GN=TRIM71 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase TRIM71 [Ceratotherium simum simum]
ENSG00000206559(ZCWPW2)	--	0.139028335	4	0.054822517	1	0.599880766	7	0.158233183	2	0.314702866	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	CW-type Zinc Finger;; PWWP domain	Zinc finger CW-type PWWP domain protein 2 GN=ZCWPW2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger CW-type PWWP domain protein 2 [Tupaia chinensis]
ENSG00000206560(ANKRD28)	--	16.18744487	1959	18.525525	2279	16.22880885	1968	16.46289733	2023	13.78931454	1669	19.598368	2392	0.986771341	0.01553467	normal	0.509587908	-0.470477104	normal	0.947513665	0.273005155	normal	0.894182217	-0.049567458	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K15502|0|pon:100456932|ANKRD28; ankyrin repeat domain 28; K15502 serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A GN=ANKRD28 OS=Homo sapiens (Human) PE=1 SV=5	R	General function prediction only	PREDICTED: serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A isoform X4 [Mustela putorius furo] 
ENSG00000206561(COLQ)	--	0.18196324	11	0.217741798	13	0.14047197	8	0.232544816	14	0.17172245	10	0.100584606	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Collagen triple helix repeat (20 copies)	Acetylcholinesterase collagenic tail peptide (Precursor) GN=COLQ OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: acetylcholinesterase collagenic tail peptide isoform 2 [Trichechus manatus latirostris]
ENSG00000206562(METTL6)	--	17.92122804	481	15.904806	493	19.28676457	533	18.15948961	494	17.617253	493	17.1598695	511	0.971455503	0.007617874	normal	0.97070389	-0.021361034	normal	0.970138451	-0.068903999	normal	0.938305293	-0.029572933	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K00599|0|ptr:743647|METTL6, PGM2L1; methyltransferase like 6; K00599 methyltransferase-like protein 6 [EC:2.1.1.-] (A)"	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain	Methyltransferase-like protein 6 GN=METTL6 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: methyltransferase-like protein 6 isoform X1 [Panthera tigris altaica] 
ENSG00000206579(XKR4)	--	0.015248703	1	0	0	0	0	0	0	0.014730703	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	XK-related protein	XK-related protein 4 GN=XKR4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: XK-related protein 4 [Ailuropoda melanoleuca]
ENSG00000211445(GPX3)-2	--	5.854197204	158	5.445340067	153	4.932046007	134	5.45069706	156	6.277491715	174	5.056950002	149	0.966925306	-0.048733854	normal	0.95620569	0.162621067	normal	0.961468583	0.143254074	normal	0.873312464	0.084716513	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000211445(GPX3)-3	--	0.337471	1	0.649104	2	0.627844	1	0.304298	1	0.328457	0	0.960347	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000211448(DIO2)	--	2.975377723	129	2.584676689	197	2.728809077	124	13.48174974	849	19.46363776	996	12.07088414	875	0	2.673297119	up	0	2.307777587	up	0	2.795711359	up	8.67E-53	2.574026007	up	--	--	--	"K17904|0|pps:100972089|DIO2; deiodinase, iodothyronine, type II; K17904 type II thyroxine 5'-deiodinase [EC:1.97.1.10] (A)"	Thyroid hormone signaling pathway (ko04919)	--	--	Iodothyronine deiodinase;; Iodothyronine deiodinase;; Iodothyronine deiodinase	Type II iodothyronine deiodinase GN=DIO2 OS=Homo sapiens (Human) PE=1 SV=4	R	General function prediction only	"PREDICTED: LOW QUALITY PROTEIN: deiodinase, iodothyronine, type II [Odobenus rosmarus divergens]"
ENSG00000211450(SELENOH)	--	85.184939	844	68.854242	715	83.56199	893	89.204669	921	88.09459	894	61.136029	618	0.974316696	0.094960385	normal	0.897911138	0.300335926	normal	0.212551083	-0.538242715	normal	0.947441852	-0.033191131	normal	--	--	--	--	--	--	--	--	Zinc finger protein ENSP00000375192 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: UPF0764 protein C16orf89-like [Camelus ferus]
ENSG00000211452(DIO1)	--	0	0	0	0	0	0	0	0	0.036428642	0	0.378143002	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: thyroxine 5'-deiodinase activity (GO:0004800);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K01562|8.66296e-167|hsa:1733|DIO1, 5DI, TXDI1; deiodinase, iodothyronine, type I (EC:1.97.1.10); K01562 type I thyroxine 5'-deiodinase [EC:1.97.1.10] (A)"	Thyroid hormone signaling pathway (ko04919)	--	--	Iodothyronine deiodinase;; Iodothyronine deiodinase	Type I iodothyronine deiodinase GN=DIO1 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: type I iodothyronine deiodinase [Bubalus bubalis]
ENSG00000211455(STK38L)	--	6.408075	400	7.129525783	386	9.81508856	403	11.569824	766	18.09731565	979	14.7470319	748	6.97E-05	0.903961842	normal	4.45E-11	1.317925421	up	0.000134255	0.881501023	normal	1.12E-07	1.047068941	up	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein serine/threonine kinase activity (GO:0004674);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08790|0|pps:100984642|STK38L; serine/threonine kinase 38 like; K08790 serine/threonine kinase 38 [EC:2.7.11.1] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like;; Protein kinase C terminal domain	Serine/threonine-protein kinase 38-like OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase 38-like [Loxodonta africana] 
ENSG00000211456(SACM1L)	--	11.8466224	583	12.71581	677	11.53124182	613	10.26474112	553	9.296397	506	10.96316031	593	0.967678552	-0.106759724	normal	0.611131509	-0.440302946	normal	0.972445977	-0.056005924	normal	0.372718601	-0.202240723	normal	[T]	Signal transduction mechanisms	Molecular Function: phosphoric ester hydrolase activity (GO:0042578);; 	--	--	[I]	Lipid transport and metabolism	SacI homology domain	Phosphatidylinositide phosphatase SAC1 GN=SACM1L OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: phosphatidylinositide phosphatase SAC1 [Oryctolagus cuniculus]
ENSG00000211460(TSN)	--	37.67181785	1787	35.11510545	1694	40.8444481	1798	28.27284884	1329	28.47945377	1362	26.46994821	1254	0.52367455	-0.457572698	normal	0.879930613	-0.335798658	normal	0.227299247	-0.527612769	normal	0.003293614	-0.441501956	normal	--	--	Molecular Function: sequence-specific DNA binding (GO:0043565);; 	--	--	[R]	General function prediction only	Translin family	Translin GN=TSN OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	translin [Bos taurus] 
ENSG00000211584(SLC48A1)	--	30.7734622	1384	31.953167	1430	30.489712	1382	25.306842	1127	24.89606	1112	28.306384	1314	0.879291843	-0.326785822	normal	0.782754411	-0.383823265	normal	0.980719304	-0.080992878	normal	0.13338175	-0.260763658	normal	--	--	Molecular Function: heme transporter activity (GO:0015232);; Biological Process: heme transport (GO:0015886);; 	"K15380|1.81188e-72|pon:100431679|SLC48A1; solute carrier family 48 (heme transporter), member 1; K15380 solute carrier family 48 (heme transporter), member 1 (A)"	--	--	--	--	Heme transporter HRG1 GN=SLC48A1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: heme transporter HRG1 [Loxodonta africana]
ENSG00000212122(TSSK1B)	--	0.0203454	1	0	0	0	0	0	0	0	0	0.0201025	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08811|0|hsa:83942|TSSK1B, SPOGA4, STK22D, TSK1, TSSK1; testis-specific serine kinase 1B (EC:2.7.11.1); K08811 testis-specific serine kinase [EC:2.7.11.1] (A)"	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Testis-specific serine/threonine-protein kinase 1 GN=FKSG81 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: testis-specific serine/threonine-protein kinase 1-like [Equus caballus] 
ENSG00000212124(TAS2R19)	--	0.274307	3	0.462666	5	0.0918893	0	0.347907	4	0.0891648	0	0.453029	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:259294|TAS2R19, MSTP058, T2R19, T2R23, T2R48, TAS2R23, TAS2R48; taste receptor, type 2, member 19; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 19 GN=TAS2R19 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 20-like [Tupaia chinensis]
ENSG00000212126(TAS2R50)	--	0.0896358	1	0.358798	4	0.0892751	0	0	0	0.263191	2	0.0887005	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:259296|TAS2R50, T2R50, T2R51, TAS2R51; taste receptor, type 2, member 50; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 50 GN=TAS2R50 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 20-like [Tupaia chinensis]
ENSG00000212127(TAS2R14)	--	0.999284	23	1.67009	38	1.45404	32	1.11947	26	1.46777	34	1.59537	37	0.986602702	0.137409141	normal	0.979629992	-0.17454339	normal	0.980858969	0.192687079	normal	0.984925516	0.040632087	normal	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:50840|TAS2R14, T2R14, TRB1; taste receptor, type 2, member 14; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R);; 7 transmembrane receptor (rhodopsin family)	Taste receptor type 2 member 14 GN=TAS2R14 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 14-like [Tupaia chinensis]
ENSG00000212128(TAS2R13)	--	0.0447244	1	0.0896311	2	0.089639	1	0.0880879	2	0.0432811	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:50838|TAS2R13, T2R13, TRB3; taste receptor, type 2, member 13; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 13 GN=TAS2R13 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 13-like [Tupaia chinensis]
ENSG00000212643(ZRSR1)	--	0.799189	50	1.474233	82	1.21332	78	1.241171	79	1.310004	72	1.506215	97	0.824413698	0.613969885	normal	0.963900942	-0.205015235	normal	0.94806513	0.300976905	normal	0.71373972	0.219545957	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[A]	RNA processing and modification	"Zinc finger C-x8-C-x5-C-x3-H type (and similar);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 1 GN=ZRSR1 OS=Homo sapiens (Human) PE=2 SV=2	A	RNA processing and modification	PREDICTED: U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 [Oryctolagus cuniculus]
ENSG00000212719(C17orf51)	--	6.506202	656	6.09121	738	7.007279	728	6.7210999	575	5.7029093	643	5.3689068	646	0.943003986	-0.2204142	normal	0.944899162	-0.219745767	normal	0.957584153	-0.180297873	normal	0.336380099	-0.207778123	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C17orf51 GN=C17orf51 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000212721(KRTAP4-11)	--	0	0	0	0	0	0	0.151117	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: keratin filament (GO:0045095);; 	--	--	[W]	Extracellular structures	"Keratin, high sulfur B2 protein;; Keratin, high sulfur B2 protein"	Keratin-associated protein 4-11 GN=KRTAP4-11 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	hypothetical protein CB1_000879014 [Camelus ferus]
ENSG00000212724(KRTAP2-3)	--	0.62301	6	0.207434	2	0.993692	9	0.717255	7	0.706066	6	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: keratin filament (GO:0045095);; 	--	--	[W]	Extracellular structures	"Keratin, high sulfur B2 protein;; Keratin, high sulfur B2 protein"	Keratin-associated protein 2-1 GN=KRTAP2-1 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	keratin associated protein-like [Bos taurus] 
ENSG00000212747(FAM127C)	--	5.50483	170	4.67557	143	5.05502	156	14.2854	442	13.4807	416	10.6447	331	3.58E-09	1.339896571	up	5.64E-11	1.509350834	up	3.47E-05	1.069710488	up	1.62E-10	1.320115903	up	--	--	--	--	--	--	--	--	Protein FAM127C GN=FAM127C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM127A-like [Galeopterus variegatus]
ENSG00000212864(RNF208)	--	2.191776275	111	2.022695857	82	2.200990573	82	2.362111227	65	1.726353092	52	1.986160444	67	0.305960221	-0.788441135	normal	0.741604096	-0.663048075	normal	0.955457764	-0.293750585	normal	0.172009626	-0.601141057	normal	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	RING finger protein 208 GN=RNF208 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 208 [Galeopterus variegatus]
ENSG00000212900(KRTAP3-2)	--	0	0	0	0	0	0	0	0	0.131134	0	0.132359	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	"Keratin, high-sulphur matrix protein"	Keratin-associated protein 3-2 GN=KRTAP3-2 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: keratin-associated protein 3-3-like [Echinops telfairi]
ENSG00000212901(KRTAP3-1)	--	0.416499	2	0	0	0.202847	0	0.789922	4	0.200966	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	"Keratin, high-sulphur matrix protein"	Keratin-associated protein 3-1 GN=KRTAP3-1 OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: keratin-associated protein 3-1 [Oryctolagus cuniculus]
ENSG00000212916(MAP10)	--	1.933836	143	1.540837	110	1.654902	114	1.816481	129	1.85247	128	1.190061	83	0.958055139	-0.177467567	normal	0.956270415	0.194730112	normal	0.868490416	-0.458976283	normal	0.810489609	-0.13270015	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Molecular Function: microtubule binding (GO:0008017);; 	--	--	--	--	Domain of unknown function;; Protein of unknown function (DUF4497)	Microtubule-associated protein 10 GN=MAP10 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: uncharacterized protein KIAA1383 homolog [Ceratotherium simum simum]
ENSG00000212993(POU5F1B)	--	0	0	0	0	0.0101943	0	0	0	0	0	0.0101948	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09367|0|hsa:5462|POU5F1B, OCT4-PG1, OCT4PG1, OTF3C, OTF3P1, POU5F1P1, POU5F1P4, POU5FLC20, POU5FLC8; POU class 5 homeobox 1B; K09367 POU domain transcription factor, class 5 (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"Putative POU domain, class 5, transcription factor 1B OS=Homo sapiens (Human) PE=5 SV=2"	K	Transcription	POU class 5 homeobox 1 [Capra hircus] 
ENSG00000213020(ZNF611)	--	2.04458059	176	5.474535449	164	2.374757646	174	2.575567556	133	2.516738731	129	1.382025848	160	0.823664558	-0.430640883	normal	0.890278824	-0.363957217	normal	0.961487835	-0.128145013	normal	0.411806356	-0.305128973	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:81856|ZNF611; zinc finger protein 611; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; BolA-like protein;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 611 GN=ZNF611 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 665-like [Oryctolagus cuniculus]
ENSG00000213023(SYT3)	--	0.552044456	28	0.718447625	35	0.4605952	18	0.335638539	16	0.991444	49	0.480335859	25	0.948658204	-0.780818823	normal	0.954762111	0.447590227	normal	0.98118188	0.434544571	normal	0.931804253	0.13125842	normal	[R]	General function prediction only	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-3 GN=SYT3 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-3 [Sus scrofa]
ENSG00000213030(CGB8)	--	0.075873	1	0.299179474	4	0.507402181	6	5.211642	65	5.512963	65	1.452217815	17	4.10E-13	4.692137958	up	2.13E-10	3.574656335	up	--	--	--	--	--	--	--	--	--	"K10045|4.00276e-90|hsa:93659|CGB5, HCG; chorionic gonadotropin, beta polypeptide 5; K10045 chorionic gonadotropin, beta polypeptide (A)"	--	--	--	Cystine-knot domain	Choriogonadotropin subunit beta variant 2 (Precursor) GN=CGB2 OS=Homo sapiens (Human) PE=2 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: lutropin subunit beta [Bos mutus]
ENSG00000213047(DENND1B)	--	2.54927337	261	2.410507419	242	1.919216771	229	2.159671146	288	2.87617474	329	2.646996546	270	0.961965716	0.11056699	normal	0.747107345	0.419398325	normal	0.938683164	0.22793268	normal	0.382441383	0.255655356	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	DENN (AEX-3) domain;; dDENN domain;; uDENN domain	DENN domain-containing protein 1B GN=DENND1B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: DENN domain-containing protein 1B [Odobenus rosmarus divergens]
ENSG00000213064(SFT2D2)	--	8.471907416	1197	8.718226071	1334	9.812814286	1205	11.280142	1729	10.972686	1666	10.35325222	1577	0.337986981	0.499146719	normal	0.918469119	0.298899431	normal	0.789605062	0.379440608	normal	0.01163152	0.390760889	normal	--	--	Biological Process: vesicle-mediated transport (GO:0016192);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Got1/Sft2-like family	Vesicle transport protein SFT2B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle transport protein SFT2B [Ceratotherium simum simum]
ENSG00000213066(FGFR1OP)	--	7.131429211	318	6.561235509	337	6.821257231	309	8.055454757	390	8.849693791	388	7.655849875	369	0.92017314	0.262468442	normal	0.950133218	0.181123533	normal	0.928714171	0.246616698	normal	0.394822885	0.229303561	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: microtubule organizing center (GO:0005815);; Biological Process: microtubule anchoring (GO:0034453);; 	K16546|0|nle:100595425|FGFR1OP; FGFR1 oncogene partner; K16546 FGFR1 oncogene partner (A)	--	--	--	FOP N terminal dimerisation domain	FGFR1 oncogene partner GN=FGFR1OP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: FGFR1 oncogene partner isoform X1 [Lipotes vexillifer]
ENSG00000213077(FAM106A)	--	1.54482	54	1.17587	41	1.65427	57	1.88154	66	1.32724	46	1.35675	48	0.967476134	0.252176204	normal	0.977706042	0.139716309	normal	0.970454473	-0.249010681	normal	0.962832754	0.052071133	normal	--	--	--	--	--	--	--	--	Protein FAM106A GN=FAM106A OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	--
ENSG00000213085(CFAP45)	--	0.355019414	17	0.100775099	5	0.019815428	0	0.061348788	3	0.212720539	9	0.206334073	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Tumour suppressor, Mitostatin"	"Protein CFAP45, mitochondrial {ECO:0000305} (Precursor) OS=Homo sapiens (Human) PE=2 SV=2"	S	Function unknown	"PREDICTED: coiled-coil domain-containing protein 19, mitochondrial [Oryctolagus cuniculus]"
ENSG00000213096(ZNF254)	--	9.954200976	490	11.74835891	519	8.477514	460	11.41069939	465	9.877924564	534	8.594241	478	0.965903214	-0.106041905	normal	0.971428016	0.019622279	normal	0.970232603	0.046933943	normal	0.977244487	-0.01338034	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|ptr:100608963|ZNF254, ZNF539; zinc finger protein 254; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; XPA protein N-terminal;; Zinc ribbon domain;; Probable zinc-binding domain;; CHY zinc finger;; C1-like domain"	Zinc finger protein 254 GN=ZNF254 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000213123(TCTEX1D2)	--	12.4456	99	15.1676	127	10.9279	92	17.1878	145	15.9447	127	14.7278	121	0.76019542	0.513105759	normal	0.967428862	-0.021174422	normal	0.909338663	0.381525374	normal	0.520594041	0.283325345	normal	--	--	--	--	--	[N]	Cell motility	Tctex-1 family	Tctex1 domain-containing protein 2 GN=TCTEX1D2 OS=Homo sapiens (Human) PE=1 SV=2	N	Cell motility	PREDICTED: tctex1 domain-containing protein 2 [Ceratotherium simum simum]
ENSG00000213145(CRIP1)	--	850.33713	3338	961.52798	3957	941.93191	3975	689.6392	3005	635.85636	2540	443.37127	1842	0.9816664	-0.182362703	normal	0.018653786	-0.660687214	normal	1.73E-09	-1.117333061	down	0.003923914	-0.631910491	normal	--	--	--	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	LIM domain	Cysteine-rich protein 1 GN=CRIP1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: cysteine-rich protein 1 [Bubalus bubalis]
ENSG00000213186(TRIM59)	--	11.61384254	1099	12.53342789	1075	12.787163	1096	14.4840929	1260	13.471778	1171	12.325243	1074	0.969162479	0.166182992	normal	0.976476256	0.101840564	normal	0.980045701	-0.037492985	normal	0.748424861	0.078473817	normal	--	--	Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K12028|0|hsa:286827|TRIM59, IFT80L, MRF1, RNF104, TRIM57, TSBF1; tripartite motif containing 59; K12028 tripartite motif-containing protein 59 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; zinc finger of C3HC4-type, RING;; RING-type zinc-finger;; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain"	Tripartite motif-containing protein 59 GN=TRIM59 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 59 isoform X1 [Mustela putorius furo] 
ENSG00000213190(MLLT11)	--	12.0225	1061	11.9594	1074	12.8949	1149	17.833	1574	17.1695	1500	12.5805	1113	0.193081855	0.537535847	normal	0.527877812	0.459991569	normal	0.979971934	-0.054144237	normal	0.146476401	0.328455203	normal	--	--	--	--	--	--	--	Drug resistance and apoptosis regulator	Protein AF1q GN=MLLT11 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: protein AF1q [Equus caballus] 
ENSG00000213199(ASIC3)	--	4.583762972	144	4.157779566	128	3.083289545	100	2.0766349	66	2.599482808	83	4.529378833	142	0.001658523	-1.137960771	down	0.561483439	-0.636965712	normal	0.79367963	0.491333899	normal	0.527978884	-0.373675973	normal	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	K04830|0|mcf:102146649|ASIC3; acid-sensing (proton-gated) ion channel 3; K04830 acid-sensing ion channel 3 (A)	Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Acid-sensing ion channel 3 GN=ASIC3 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: acid-sensing ion channel 3 isoform X2 [Mustela putorius furo] 
ENSG00000213213(CCDC183)	--	0.264356	10	0.102777	4	0.226784	8	0.0785161	3	0.154718	5	0.131162	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 183 GN=CCDC183 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized coiled-coil domain-containing protein KIAA1984 homolog [Ceratotherium simum simum]
ENSG00000213214(ARHGEF35)	--	0	0	0	0	0	0	0.54795	27	0.363535	17	0.287192	14	6.73E-05	4.200602614	up	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Rho guanine nucleotide exchange factor 5/35	Rho guanine nucleotide exchange factor 35 GN=ARHGEF35 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 5 [Galeopterus variegatus]
ENSG00000213221(DNLZ)	--	14.83770706	139	20.317563	207	19.4465732	193	16.4054532	156	14.0167398	127	13.78351802	132	0.962040338	0.134227903	normal	0.131165111	-0.719448879	normal	0.571264156	-0.55110102	normal	0.240621618	-0.398830123	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	"K17808|2.20118e-97|hsa:728489|DNLZ, C9orf151, HEP, HEP1, TIMM15, ZIM17, bA413M3.2; DNL-type zinc finger; K17808 mitochondrial protein import protein ZIM17 (A)"	--	[S]	Function unknown	DNL zinc finger	DNL-type zinc finger protein (Precursor) GN=DNLZ OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: DNL-type zinc finger protein [Chrysochloris asiatica]
ENSG00000213231(TCL1B)	--	0.0598632	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K16836|5.94078e-89|hsa:9623|TCL1B, SYN-1, TML1; T-cell leukemia/lymphoma 1B; K16836 T-cell leukemia/lymphoma 1B (A)"	PI3K-Akt signaling pathway (ko04151)	--	--	TCL1/MTCP1 family	T-cell leukemia/lymphoma protein 1B GN=TCL1B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: T-cell leukemia/lymphoma protein 1B [Mustela putorius furo] 
ENSG00000213316(LTC4S)	--	0	0	0	0	0	0	0.281329669	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K00807|1.37151e-59|hsa:4056|LTC4S; leukotriene C4 synthase (EC:4.4.1.20); K00807 leukotriene-C4 synthase [EC:4.4.1.20] (A)	Arachidonic acid metabolism (ko00590)	--	--	MAPEG family	Leukotriene C4 synthase GN=LTC4S OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: leukotriene C4 synthase [Orycteropus afer afer]
ENSG00000213339(QTRT1)	--	13.48909434	298	16.74252333	378	17.170698	396	17.721155	411	17.60802308	415	20.255371	468	0.684953394	0.43109421	normal	0.962691362	0.112867489	normal	0.935184855	0.231901141	normal	0.317214788	0.250967116	normal	[J]	"Translation, ribosomal structure and biogenesis"	"Biological Process: tRNA modification (GO:0006400);; Molecular Function: transferase activity, transferring pentosyl groups (GO:0016763);; "	K00773|0|pps:100975608|QTRT1; queuine tRNA-ribosyltransferase 1; K00773 queuine tRNA-ribosyltransferase [EC:2.4.2.29] (A)	--	[A]	RNA processing and modification	Queuine tRNA-ribosyltransferase	Queuine tRNA-ribosyltransferase GN=QTRT1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: queuine tRNA-ribosyltransferase [Galeopterus variegatus]
ENSG00000213347(MXD3)	--	17.59171322	706	13.08864625	511	12.33357594	539	19.21604597	791	15.88078352	672	14.60720015	707	0.967807706	0.132903908	normal	0.791935035	0.37274678	normal	0.765596942	0.382194464	normal	0.198369562	0.283667193	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09114|3.50318e-100|mcf:102122803|MXD3; MAX dimerization protein 3; K09114 MAX dimerization protein (A)	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Max dimerization protein 3 GN=MXD3 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: max dimerization protein 3 isoform X1 [Pteropus alecto]
ENSG00000213390(ARHGAP19)	--	3.967915129	379	2.596352204	247	3.906661728	366	3.329009581	319	3.259452243	309	2.1322934	201	0.910810048	-0.278242333	normal	0.90035445	0.300023982	normal	0.001763671	-0.86802646	normal	0.535298568	-0.280998945	normal	--	--	Biological Process: signal transduction (GO:0007165);; 	--	--	[T]	Signal transduction mechanisms	RhoGAP domain	Rho GTPase-activating protein 19 GN=ARHGAP19 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 19 isoform X2 [Canis lupus familiaris]
ENSG00000213401(MAGEA12)	--	0	0	0	0	0	0	0.368702462	11	0.3874109	11	0.368243802	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 12 GN=MAGEA12 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: melanoma-associated antigen 11-like [Equus caballus]
ENSG00000213413(PVRIG)	--	2.74884	73	2.86499	78	2.69554	74	1.61209	43	1.57978	41	2.29684	62	0.646518547	-0.772941881	normal	0.307520883	-0.924139633	normal	0.963128618	-0.257785389	normal	0.176543626	-0.644116081	normal	--	--	--	--	--	--	--	--	Transmembrane protein PVRIG GN=PVRIG OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein PVRIG [Galeopterus variegatus]
ENSG00000213420(GPC2)	--	1.878928	78	1.223897844	54	1.249674573	53	0.799999904	33	1.539715254	62	0.591760564	25	0.025314347	-1.233344452	normal	0.971721952	0.173348968	normal	0.452601549	-1.047860249	normal	0.281185526	-0.646171505	normal	--	--	Cellular Component: proteinaceous extracellular matrix (GO:0005578);; Cellular Component: membrane (GO:0016020);; Molecular Function: heparan sulfate proteoglycan binding (GO:0043395);; 	K08108|0|hsa:221914|GPC2; glypican 2; K08108 glypican 2 (cerebroglycan) (A)	--	[T]	Signal transduction mechanisms	Glypican	Secreted glypican-2 (Precursor) GN=GPC2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: glypican-2 [Tupaia chinensis]
ENSG00000213424(KRT222)	--	0.613546	24	0.246322631	10	0.764577	24	1.24488	49	2.338946	93	1.18612044	49	0.678434966	0.955329675	normal	7.02E-12	3.017479929	up	0.637455151	0.977520522	normal	0.016387386	1.699407354	normal	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	--	--	--	--	Intermediate filament protein	Keratin-like protein KRT222 GN=KRT222 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: keratin-like protein KRT222 [Orcinus orca] 
ENSG00000213445(SIPA1)	--	13.27376449	784	10.69524628	622	12.3111169	750	8.38198484	461	11.87476859	605	6.530535679	337	0.001086372	-0.794862024	normal	0.971660432	-0.061254979	normal	2.81E-08	-1.158853067	down	0.022914502	-0.641453431	normal	--	--	Molecular Function: GTPase activator activity (GO:0005096);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of small GTPase mediated signal transduction (GO:0051056);; 	K08013|0|pps:100985515|SIPA1; signal-induced proliferation-associated 1; K08013 signal-induced proliferation-associated gene 1 (A)	Rap1 signaling pathway (ko04015);; Leukocyte transendothelial migration (ko04670)	[T]	Signal transduction mechanisms	Rap/ran-GAP;; PDZ domain (Also known as DHR or GLGF)	Signal-induced proliferation-associated protein 1 GN=SIPA1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: signal-induced proliferation-associated protein 1 isoform X4 [Felis catus]
ENSG00000213465(ARL2)	--	126.361985	2017	129.086411	2120	118.681462	1977	123.337714	2028	121.552279	1927	112.865607	1838	0.986845215	-0.022968247	normal	0.978425362	-0.159015216	normal	0.982595011	-0.113377577	normal	0.655787228	-0.099383634	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K07943|7.81276e-131|ggo:101132849|ARL2; ADP-ribosylation factor-like protein 2 isoform 1; K07943 ADP-ribosylation factor-like protein 2 (A)	--	[UZ]	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	ADP-ribosylation factor family;; Signal recognition particle receptor beta subunit;; Ras family;; Gtr1/RagA G protein conserved region;; Miro-like protein;; 50S ribosome-binding GTPase;; Elongation factor Tu GTP binding domain	ADP-ribosylation factor-like protein 2 GN=ARL2 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor-like protein 2 isoform X2 [Myotis lucifugus] 
ENSG00000213471(TTLL13P)	--	0.111186	7	0.156698	10	0.200105	12	0.221227	14	0.0925764	5	0.125714	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	K16582|0|ptr:746756|TTLL13; tubulin polyglutamylase TTLL13; K16582 tubulin polyglutamylase TTLL6/13 [EC:6.-.-.-] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin polyglutamylase TTLL13 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tubulin polyglutamylase TTLL13-like [Galeopterus variegatus]
ENSG00000213512(GBP7)	--	0	0	0	0	0.0382849	1	0.0385843	2	0.0376846	1	0.019262	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	[R]	General function prediction only	"Guanylate-binding protein, N-terminal domain;; Guanylate-binding protein, C-terminal domain"	Guanylate-binding protein 7 GN=GBP7 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: guanylate-binding protein 4-like [Galeopterus variegatus]
ENSG00000213533(TMEM110)	--	5.305039113	461	6.771698851	484	5.420565331	511	5.156900109	473	5.568179002	444	5.732734574	425	0.971048344	0.006220702	normal	0.959434164	-0.145399408	normal	0.912947195	-0.273263798	normal	0.615913318	-0.139011696	normal	--	--	--	--	--	--	--	Vaculolar membrane protein	Transmembrane protein 110 GN=TMEM110 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: musculoskeletal embryonic nuclear protein 1-like isoform 1 [Odobenus rosmarus divergens]
ENSG00000213578(CPLX3)	--	0	0	0	0	0	0	0	0	0.021351	0	0.021695	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: neurotransmitter transport (GO:0006836);; Molecular Function: syntaxin binding (GO:0019905);; 	"K15295|2.30794e-92|hsa:594855|CPLX3, CPX-III, CPXIII; complexin 3; K15295 complexin-3/4 (A)"	Synaptic vesicle cycle (ko04721)	--	--	Synaphin protein	Complexin-3 (Precursor) GN=CPLX3 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: complexin-3 [Equus caballus]
ENSG00000213585(VDAC1)	--	180.2882501	5620	173.0006855	5424	175.7617901	5475	197.9065707	6225	171.8549138	5337	165.8891901	5214	0.992383032	0.116641137	normal	0.993319425	-0.044742149	normal	0.992889427	-0.078737535	normal	1	0.000493456	normal	--	--	Cellular Component: mitochondrial outer membrane (GO:0005741);; Biological Process: transmembrane transport (GO:0055085);; 	K05862|0|ptr:745717|VDAC1; voltage-dependent anion channel 1; K05862 voltage-dependent anion channel protein 1 (A)	Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Parkinson's disease (ko05012);; Huntington's disease (ko05016);; Influenza A (ko05164);; HTLV-I infection (ko05166)	[P]	Inorganic ion transport and metabolism	Eukaryotic porin	Voltage-dependent anion-selective channel protein 1 GN=VDAC1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: voltage-dependent anion-selective channel protein 1 isoform X1 [Equus caballus]
ENSG00000213593(TMX2)	--	70.5325	1822	64.9005	1700	66.8052	1731	66.5354	1755	65.2159	1687	66.8218	1756	0.983700535	-0.084811313	normal	0.984615117	-0.032472333	normal	0.985548494	0.012384935	normal	0.895734901	-0.03640347	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin	Thioredoxin-related transmembrane protein 2 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin-related transmembrane protein 2 [Ailuropoda melanoleuca]
ENSG00000213614(HEXA)	--	106.8027063	3325	119.5531456	3736	96.818497	3037	114.3024588	3551	104.263079	3293	139.0148794	4365	0.990427451	0.064010133	normal	0.979840331	-0.20343072	normal	0.340020887	0.514828331	normal	0.651762877	0.129692426	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K12373|0|hsa:3073|HEXA, TSD; hexosaminidase A (alpha polypeptide) (EC:3.2.1.52); K12373 hexosaminidase [EC:3.2.1.52] (A)"	Other glycan degradation (ko00511);; Amino sugar and nucleotide sugar metabolism (ko00520);; Glycosaminoglycan degradation (ko00531);; Glycosphingolipid biosynthesis - globo series (ko00603);; Glycosphingolipid biosynthesis - ganglio series (ko00604);; Lysosome (ko04142)	[G]	Carbohydrate transport and metabolism	"Glycosyl hydrolase family 20, catalytic domain;; beta-acetyl hexosaminidase like"	Beta-hexosaminidase subunit alpha (Precursor) GN=HEXA OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: beta-hexosaminidase subunit alpha [Galeopterus variegatus]
ENSG00000213619(NDUFS3)	--	58.992572	694	50.088388	700	54.256732	761	49.457448	698	50.417065	690	50.3286828	687	0.975118759	-0.022491241	normal	0.974011081	-0.042093521	normal	0.96374571	-0.155552298	normal	0.786760395	-0.075653794	normal	[C]	Energy production and conversion	Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K03936|0|hsa:4722|NDUFS3, CI-30; NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3); K03936 NADH dehydrogenase (ubiquinone) Fe-S protein 3 [EC:1.6.5.3 1.6.99.3] (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	"Respiratory-chain NADH dehydrogenase, 30 Kd subunit"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial (Precursor) GN=NDUFS3 OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial [Odobenus rosmarus divergens]"
ENSG00000213626(LBH)	--	14.83063168	736	20.25990377	1064	17.36904437	897	64.08368805	3186	70.674801	3519	59.588015	3026	0	2.080862821	up	0	1.702831394	up	0	1.744240282	up	7.94E-44	1.82987808	up	--	--	--	--	--	--	--	"Cardiac transcription factor regulator, Developmental protein"	Protein LBH GN=LBH OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: protein LBH [Condylura cristata]
ENSG00000213638(ADAT3)	--	38.61084075	1543	38.62353849	1555	39.40541007	1651	37.2379913	1560	39.30745404	1614	42.1036519	1757	0.98432861	-0.015009433	normal	0.983923245	0.032268637	normal	0.983369614	0.081410334	normal	0.905060143	0.033538354	normal	[FJ]	"Nucleotide transport and metabolism;; Translation, ribosomal structure and biogenesis"	Biological Process: tRNA wobble adenosine to inosine editing (GO:0002100);; Molecular Function: tRNA-specific adenosine deaminase activity (GO:0008251);; 	"K15442|0|hsa:113179|ADAT3, FWP005, MRT36, MST121, MSTP121, S863-5, TAD3; adenosine deaminase, tRNA-specific 3; K15442 tRNA-specific adenosine deaminase 3 (A)"	--	[A]	RNA processing and modification	Cytidine and deoxycytidylate deaminase zinc-binding region	Probable inactive tRNA-specific adenosine deaminase-like protein 3 GN=ADAT3 OS=Homo sapiens (Human) PE=1 SV=1	F	Nucleotide transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: adenosine deaminase, tRNA-specific 3 [Pteropus alecto]"
ENSG00000213639(PPP1CB)	--	109.6868649	5281	112.017081	5545	117.5809622	5562	90.24473816	4586	86.46710402	4041	91.38522265	4407	0.979409154	-0.234333812	normal	0.587118582	-0.477748343	normal	0.927256514	-0.343992967	normal	0.030472775	-0.351683874	normal	[T]	Signal transduction mechanisms	Molecular Function: hydrolase activity (GO:0016787);; 	"K06269|0|tup:102496931|PPP1CB; protein phosphatase 1, catalytic subunit, beta isozyme; K06269 serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16] (A)"	mRNA surveillance pathway (ko03015);; cGMP-PKG signaling pathway (ko04022);; cAMP signaling pathway (ko04024);; Oocyte meiosis (ko04114);; Adrenergic signaling in cardiomyocytes (ko04261);; Vascular smooth muscle contraction (ko04270);; Hippo signaling pathway (ko04390);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Long-term potentiation (ko04720);; Dopaminergic synapse (ko04728);; Inflammatory mediator regulation of TRP channels (ko04750);; Regulation of actin cytoskeleton (ko04810);; Insulin signaling pathway (ko04910);; Oxytocin signaling pathway (ko04921);; Amphetamine addiction (ko05031);; Alcoholism (ko05034);; Herpes simplex infection (ko05168);; Proteoglycans in cancer (ko05205)	[TR]	Signal transduction mechanisms;; General function prediction only	Calcineurin-like phosphoesterase	Serine/threonine-protein phosphatase PP1-beta catalytic subunit GN=PPP1CB OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein phosphatase PP1-beta catalytic subunit [Galeopterus variegatus] 
ENSG00000213658(LAT)	--	2.128438507	40	1.72903015	40	1.789912	38	1.648874417	34	1.015927477	17	1.999158638	45	0.978000304	-0.254673726	normal	0.51296494	-1.185216472	normal	0.976586965	0.227312542	normal	0.676163341	-0.318255889	normal	--	--	Biological Process: signal transduction (GO:0007165);; Cellular Component: membrane (GO:0016020);; 	K07362|4.60318e-113|ptr:743295|LAT; linker for activation of T cells; K07362 linker for activation of T cells (A)	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; NF-kappa B signaling pathway (ko04064);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666)	--	--	Linker for activation of T-cells	Linker for activation of T-cells family member 1 GN=LAT OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: linker for activation of T-cells family member 1 [Trichechus manatus latirostris]
ENSG00000213672(NCKIPSD)	--	6.886858026	431	7.86216346	445	6.32246863	402	6.275738737	388	6.05668675	366	6.819640635	388	0.951386698	-0.181780071	normal	0.891237772	-0.302253579	normal	0.968120818	-0.059203575	normal	0.501509077	-0.183696642	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Protein of unknown function (DUF2013);; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	NCK-interacting protein with SH3 domain GN=NCKIPSD OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: NCK-interacting protein with SH3 domain isoform 1 [Tursiops truncatus]
ENSG00000213699(SLC35F6)	--	26.02242	1832	27.60587	1984	29.73273	2101	24.47099	1726	23.75499	1678	30.78792	2211	0.981477355	-0.116718429	normal	0.948382928	-0.26287769	normal	0.98647043	0.065285609	normal	0.721029296	-0.095891142	normal	[GER]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism;; General function prediction only	Cellular Component: Golgi membrane (GO:0000139);; Molecular Function: sugar:proton symporter activity (GO:0005351);; Biological Process: transport (GO:0006810);; Biological Process: carbohydrate transport (GO:0008643);; Cellular Component: membrane (GO:0016020);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Eukaryotic protein of unknown function (DUF914);; EamA-like transporter family;; Nucleotide-sugar transporter;; Triose-phosphate Transporter family;; UAA transporter family	Solute carrier family 35 member F6 (Precursor) GN=SLC35F6 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: solute carrier family 35 member F6 [Tupaia chinensis] 
ENSG00000213714(FAM209B)	--	0.128055	1	0.505972	4	0	0	0	0	0	0	0.124909	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	FAM209 family	Protein FAM209B (Precursor) GN=FAM209B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM209B [Canis lupus familiaris]
ENSG00000213719(CLIC1)	--	196.8096825	4687	191.9158674	4547	196.2186558	4758	218.4231374	5343	189.2798433	4567	167.9588628	4127	0.988995474	0.158104394	normal	0.992656214	-0.015089765	normal	0.981550656	-0.213480354	normal	0.959389613	-0.017303907	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: protein binding (GO:0005515);; 	K05021|1.48951e-177|ptr:462564|CLIC1; chloride intracellular channel 1; K05021 chloride intracellular channel protein 1 (A)	--	[P]	Inorganic ion transport and metabolism	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain"	Chloride intracellular channel protein 1 GN=CLIC1 OS=Homo sapiens (Human) PE=1 SV=4	P	Inorganic ion transport and metabolism	PREDICTED: chloride intracellular channel protein 1 [Galeopterus variegatus]
ENSG00000213741(RPS29)	--	1762.1321	1239	1845.939086	1363	1697.108431	1331	1973.519479	1670	1903.96357	1327	1840.127735	1413	0.738067315	0.39941168	normal	0.981295291	-0.059976304	normal	0.981101024	0.077873568	normal	0.486416227	0.143378052	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02980|7.61565e-43|hsa:6235|RPS29, DBA13, S29; ribosomal protein S29; K02980 small subunit ribosomal protein S29e (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S14p/S29e	40S ribosomal protein S29 GN=RPS29 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S29 [Myotis brandtii]
ENSG00000213759(UGT2B11)	--	0.115149	4	0.0870159	3	0.145079	4	0.0575252	2	0.196357	6	0.0861093	3	--	--	--	--	--	--	--	--	--	--	--	--	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	"Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K00699|0|hsa:10720|UGT2B11; UDP glucuronosyltransferase 2 family, polypeptide B11 (EC:2.4.1.17); K00699 glucuronosyltransferase [EC:2.4.1.17] (A)"	Pentose and glucuronate interconversions (ko00040);; Ascorbate and aldarate metabolism (ko00053);; Steroid hormone biosynthesis (ko00140);; Starch and sucrose metabolism (ko00500);; Retinol metabolism (ko00830);; Porphyrin and chlorophyll metabolism (ko00860);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	[GC]	Carbohydrate transport and metabolism;; Energy production and conversion	UDP-glucoronosyl and UDP-glucosyl transferase;; Glycosyltransferase family 28 C-terminal domain	UDP-glucuronosyltransferase 2B11 (Precursor) GN=UGT2B11 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: UDP-glucuronosyltransferase 2B4-like isoform X1 [Galeopterus variegatus]
ENSG00000213760(ATP6V1G2)	--	0.618030039	14	0.467420517	12	1.0975426	23	0.572146465	14	0.85510018	22	0.565358653	15	--	--	--	0.965785531	0.779604691	normal	0.977560873	-0.577621109	normal	--	--	--	--	--	--	"K02152|5.91095e-57|pps:100980405|ATP6V1G2; ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2; K02152 V-type H+-transporting ATPase subunit G (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	Vacuolar (H+)-ATPase G subunit	V-type proton ATPase subunit G 2 GN=ATP6V1G2 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	"V-type proton ATPase subunit G 2, partial [Bos mutus]"
ENSG00000213762(ZNF134)	--	6.025742	541	6.84008	547	6.174781	536	7.220276	596	5.7432151	531	6.8753788	639	0.967471861	0.108557679	normal	0.970015551	-0.064075721	normal	0.931674978	0.244658522	normal	0.722470756	0.099870423	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 134 GN=ZNF134 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 134-like [Equus caballus]
ENSG00000213780(GTF2H4)	--	9.36104	265	9.948685	286	9.367944	269	11.554828	327	12.986955	365	11.231035	318	0.917618933	0.271049266	normal	0.871298681	0.328911946	normal	0.935764668	0.231928642	normal	0.303885964	0.279397373	normal	[KL]	"Transcription;; Replication, recombination and repair"	Cellular Component: core TFIIH complex (GO:0000439);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Cellular Component: nucleus (GO:0005634);; Biological Process: nucleotide-excision repair (GO:0006289);; 	K03144|0|mcf:101926545|General transcription factor IIH polypeptide 4; K03144 transcription initiation factor TFIIH subunit 4 (A)	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420);; Viral carcinogenesis (ko05203)	[KL]	"Transcription;; Replication, recombination and repair"	Transcription factor Tfb2	General transcription factor IIH subunit 4 GN=GTF2H4 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: general transcription factor IIH subunit 4 isoform X1 [Panthera tigris altaica] 
ENSG00000213782(DDX47)	--	42.04364907	1319	39.19911195	1230	45.39410768	1411	45.36900844	1434	49.3410079	1535	38.63001706	1207	0.980369152	0.089668009	normal	0.916453964	0.297825423	normal	0.952580926	-0.233313091	normal	0.831404474	0.055214292	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	"K14777|0|hsa:51202|DDX47, E4-DBP, HQ0256, MSTP162, RRP3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 (EC:3.6.4.13); K14777 ATP-dependent RNA helicase DDX47/RRP3 [EC:3.6.4.13] (A)"	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Probable ATP-dependent RNA helicase DDX47 GN=DDX47 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX47 isoform X1 [Ursus maritimus]
ENSG00000213793(ZNF888)	--	0.02685	2	0.0534859	4	0.0402616	2	0.026531	2	0.0259829	1	0.066484	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; BolA-like protein;; C1-like domain;; Transposase zinc-ribbon domain;; XPA protein N-terminal"	Zinc finger protein 845 GN=ZNF845 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 665-like [Oryctolagus cuniculus]
ENSG00000213799(ZNF845)	--	4.271593469	362	3.677426277	350	5.432402988	419	3.255223277	299	2.577777844	241	3.071180061	294	0.892057179	-0.305248322	normal	0.333810383	-0.556830932	normal	0.404860031	-0.517185153	normal	0.0434216	-0.460512761	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:91664|ZNF845; zinc finger protein 845; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; BolA-like protein;; Prokaryotic RING finger family 1;; Methyl-CpG binding domain;; Restriction endonuclease fold toxin 7"	Zinc finger protein 845 GN=ZNF845 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	"PREDICTED: zinc finger protein 845-like, partial [Lipotes vexillifer]"
ENSG00000213809(KLRK1)	--	0.135745437	4	0.0686697	2	0	0	0.101850221	3	0.099023697	2	0.1876915	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06728|1.94794e-161|hsa:100528032|KLRC4-KLRK1; KLRC4-KLRK1 readthrough; K06728 killer cell lectin-like receptor subfamily K member 1 (A)	Natural killer cell mediated cytotoxicity (ko04650);; Malaria (ko05144)	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain;; UL45 protein	NKG2-D type II integral membrane protein GN=KLRK1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: NKG2-D type II integral membrane protein-like [Loxodonta africana]
ENSG00000213853(EMP2)	--	13.12510792	1093	13.12335935	1174	14.65761999	1123	10.95870414	1029	12.66302718	1024	12.92706548	932	0.974596999	-0.117712103	normal	0.954322378	-0.218341818	normal	0.922547468	-0.276837659	normal	0.28447482	-0.205046728	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Epithelial membrane protein 2 GN=EMP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: epithelial membrane protein 2 [Physeter catodon]
ENSG00000213859(KCTD11)	--	10.5499	542	10.8279	566	11.0555	576	12.6851	652	8.86767	451	9.24175	476	0.93623976	0.235138458	normal	0.836186559	-0.348056867	normal	0.906581262	-0.282581241	normal	0.713277133	-0.115133398	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD11 GN=KCTD11 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein KCTD11 [Tupaia chinensis] 
ENSG00000213889(PPM1N)	--	8.45742	118	7.999504	112	6.834983641	99	3.925227155	55	3.668644	51	4.509121489	62	0.008359737	-1.110412219	down	0.009069604	-1.133096821	down	0.642824245	-0.670394589	normal	0.008082639	-0.990745263	normal	[T]	Signal transduction mechanisms	Molecular Function: magnesium ion binding (GO:0000287);; Molecular Function: catalytic activity (GO:0003824);; Molecular Function: phosphoprotein phosphatase activity (GO:0004721);; Molecular Function: manganese ion binding (GO:0030145);; 	--	--	[T]	Signal transduction mechanisms	"Protein phosphatase 2C;; Protein serine/threonine phosphatase 2C, C-terminal domain;; Protein phosphatase 2C"	Probable protein phosphatase 1N GN=PPM1N OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: probable protein phosphatase 1N [Tursiops truncatus]
ENSG00000213892(CEACAM16)	--	0.032739414	1	0	0	0.031194346	0	0	0	0	0	0.095397675	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06499|0|hsa:388551|CEACAM16, CEAL2, DFNA4B; carcinoembryonic antigen-related cell adhesion molecule 16; K06499 carcinoembryonic antigen-related cell adhesion molecule (A)"	--	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Carcinoembryonic antigen-related cell adhesion molecule 16 (Precursor) GN=CEACAM16 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	carcinoembryonic antigen-related cell adhesion molecule 16 precursor [Canis lupus familiaris]
ENSG00000213901(SLC23A3)	--	0.241068044	7	0.473019382	15	0.270093496	7	0.136727294	4	0.03370323	0	0.032949247	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: transporter activity (GO:0005215);; Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14612|0|ptr:459956|SLC23A3; solute carrier family 23, member 3; K14612 solute carrier family 23 (nucleobase transporter), member 3 (A)"	--	[F]	Nucleotide transport and metabolism	Permease family	Solute carrier family 23 member 3 GN=SLC23A3 OS=Homo sapiens (Human) PE=2 SV=2	F	Nucleotide transport and metabolism	PREDICTED: solute carrier family 23 member 3 isoform 1 [Orcinus orca]
ENSG00000213918(DNASE1)	--	3.202585356	413	5.320322446	570	5.225466509	573	3.19935301	450	2.935633045	355	3.866772278	552	0.966304707	0.092620812	normal	0.01935326	-0.702185478	normal	0.971356534	-0.061991608	normal	0.587755221	-0.217859942	normal	--	--	--	"K11994|0|hsa:1773|DNASE1, DNL1, DRNI; deoxyribonuclease I (EC:3.1.21.1); K11994 deoxyribonuclease-1 [EC:3.1.21.1] (A)"	--	--	--	Endonuclease/Exonuclease/phosphatase family	Deoxyribonuclease-1 (Precursor) GN=DNASE1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: deoxyribonuclease-1 isoform X1 [Pteropus alecto] 
ENSG00000213923(CSNK1E)	--	31.54740503	1550	25.93274842	1376	32.36515949	1578	32.44468593	1532	31.52555793	1517	26.89114418	1294	0.983633692	-0.047636685	normal	0.978277414	0.119189267	normal	0.91922137	-0.294239094	normal	0.761082241	-0.074004685	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K08960|0|nle:100607246|CSNK1E; casein kinase 1, epsilon; K08960 casein kinase 1, epsilon [EC:2.7.11.1] (A)"	FoxO signaling pathway (ko04068);; Wnt signaling pathway (ko04310);; Hedgehog signaling pathway (ko04340);; Hippo signaling pathway (ko04390);; Circadian rhythm (ko04710)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Casein kinase I isoform epsilon GN=CSNK1E OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: casein kinase I isoform epsilon isoform X7 [Mustela putorius furo] 
ENSG00000213927(CCL27)	--	0.261735	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	K16598|1.32411e-68|ptr:100610389|CCL27; chemokine (C-C motif) ligand 27; K16598 C-C motif chemokine 27 (A)	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	C-C motif chemokine 27 (Precursor) GN=CCL27 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: c-C motif chemokine 27 [Equus caballus] 
ENSG00000213928(IRF9)	--	5.944476205	222	6.372602	199	5.710534785	209	6.834666012	213	7.374035198	255	8.294142828	275	0.963753867	-0.089903206	normal	0.882824748	0.334054685	normal	0.823643014	0.385200158	normal	0.520456388	0.217622818	normal	--	--	"Molecular Function: regulatory region DNA binding (GO:0000975);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K04693|0|hsa:10379|IRF9, IRF-9, ISGF3, ISGF3G, p48; interferon regulatory factor 9; K04693 interferon regulatory factor 9 (A)"	Osteoclast differentiation (ko04380);; Jak-STAT signaling pathway (ko04630);; Hepatitis C (ko05160);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Viral carcinogenesis (ko05203)	--	--	Interferon regulatory factor transcription factor;; Interferon-regulatory factor 3	Interferon regulatory factor 9 GN=IRF9 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: interferon regulatory factor 9 [Galeopterus variegatus]
ENSG00000213937(CLDN9)	--	0.0566159	2	0.0277079	1	0.0810625	2	0.198041	7	0.109924	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06087|2.07279e-96|mcf:102139977|CLDN9, Claudin-9; claudin 9; K06087 claudin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-9 GN=CLDN9 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: claudin-9 [Balaenoptera acutorostrata scammoni]
ENSG00000213967(ZNF726)	--	1.711897296	36	1.304614743	29	2.024899911	43	0.879173471	20	0.969203867	20	1.360235448	30	0.897690201	-0.830612648	normal	0.970927069	-0.524371912	normal	0.95540143	-0.50624079	normal	0.328119024	-0.645023803	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:100995955|ZNF726; zinc finger protein 726; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; XPA protein N-terminal;; C1-like domain;; Probable zinc-binding domain"	Zinc finger protein 726 GN=ZNF726 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000213977(TAX1BP3)	--	88.45412	1928	112.85734	2518	100.91455	2255	147.30255	3250	139.76303	3025	133.57851	2933	0.002677933	0.722054586	normal	0.966594059	0.243096941	normal	0.849892006	0.370739587	normal	0.00332055	0.436970663	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	PDZ domain (Also known as DHR or GLGF);; PDZ domain	Tax1-binding protein 3 OS=Homo sapiens (Human) PE=1 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: tax1-binding protein 3 [Ailuropoda melanoleuca] 
ENSG00000213995(NAXD)	--	7.775915806	348	6.653681353	307	8.384916	383	9.986158412	448	11.1063259	496	9.587545507	433	0.860493469	0.332283352	normal	0.047810748	0.668062724	normal	0.954753117	0.168106565	normal	0.077237888	0.386809838	normal	[G]	Carbohydrate transport and metabolism	Molecular Function: ADP-dependent NAD(P)H-hydrate dehydratase activity (GO:0052855);; 	K17757|0|ptr:452663|CARKD; carbohydrate kinase domain containing; K17757 ATP-dependent NAD(P)H-hydrate dehydratase [EC:4.2.1.93] (A)	--	[G]	Carbohydrate transport and metabolism	Carbohydrate kinase	ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: ATP-dependent (S)-NAD(P)H-hydrate dehydratase isoform X1 [Equus przewalskii]
ENSG00000213996(TM6SF2)	--	0.0469599	1	0.0461331	1	0.0451589	0	0.04661	1	0.274357	5	0.0463171	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF2781)	Transmembrane 6 superfamily member 2 GN=TM6SF2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: transmembrane 6 superfamily member 2 [Orycteropus afer afer]
ENSG00000214013(GANC)	--	2.6359828	208	2.396150895	184	2.554961443	187	2.969543909	183	3.251133672	210	3.0631777	218	0.945818565	-0.213886268	normal	0.953747969	0.1679641	normal	0.945988375	0.211413511	normal	0.908687153	0.056915312	normal	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	"K12317|0|nle:100594252|GANC; glucosidase, alpha; neutral C; K12317 neutral alpha-glucosidase C [EC:3.2.1.20] (A)"	Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500)	[GMO]	"Carbohydrate transport and metabolism;; Cell wall/membrane/envelope biogenesis;; Posttranslational modification, protein turnover, chaperones"	Glycosyl hydrolases family 31;; Galactose mutarotase-like	Neutral alpha-glucosidase C GN=GANC OS=Homo sapiens (Human) PE=2 SV=3	G	Carbohydrate transport and metabolism	PREDICTED: neutral alpha-glucosidase C [Ceratotherium simum simum]
ENSG00000214021(TTLL3)	--	87.20458102	2452	96.50962	2830	95.82272054	2736	127.1674044	3466	118.3930711	3153	108.7539027	3166	0.537908612	0.468232559	normal	0.985640151	0.13442848	normal	0.977500374	0.202197603	normal	0.115734086	0.265872848	normal	--	--	Biological Process: cellular protein modification process (GO:0006464);; 	"K16608|0|hsa:26140|TTLL3, HOTTL; tubulin tyrosine ligase-like family, member 3; K16608 tubulin monoglycylase TTLL3/8 [EC:6.3.2.-] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Tubulin-tyrosine ligase family	Tubulin monoglycylase TTLL3 GN=TTLL3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: tubulin monoglycylase TTLL3 [Ursus maritimus]
ENSG00000214026(MRPL23)	--	29.06313024	268	24.46207156	229	28.1673523	263	28.5783	271	29.2276469	261	22.497297	215	0.967274995	-0.014688672	normal	0.952944373	0.166246738	normal	0.90790192	-0.297124621	normal	0.918663533	-0.046592351	normal	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02892|1.02948e-66|hsa:102724828|39S ribosomal protein L23, mitochondrial-like; K02892 large subunit ribosomal protein L23 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L23	"39S ribosomal protein L23, mitochondrial GN=MRPL23 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L23, mitochondrial isoform X3 [Tupaia chinensis] "
ENSG00000214029(ZNF891)	--	1.316549243	332	1.331611503	335	1.269756289	313	1.1293	285	1.111535989	276	1.2340917	311	0.927701303	-0.249804325	normal	0.898273711	-0.299427564	normal	0.967955878	-0.017454913	normal	0.532933219	-0.189516787	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:101060200|ZNF891; zinc finger protein 891; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 891 GN=ZNF891 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 891 [Balaenoptera acutorostrata scammoni]
ENSG00000214050(FBXO16)	--	4.071771797	69	1.872946278	53	5.050494359	94	2.277009872	47	3.094482041	73	2.407724099	48	0.883419737	-0.569308616	normal	0.931575975	0.429984965	normal	0.138650844	-0.955998906	normal	0.490663328	-0.382606341	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K10299|0|pps:100986986|FBXO16; F-box protein 16; K10299 F-box protein 16 (A)	--	[R]	General function prediction only	F-box-like;; F-box domain	F-box only protein 16 GN=FBXO16 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: F-box only protein 16 isoform 1 [Ceratotherium simum simum]
ENSG00000214063(TSPAN4)	--	110.0409134	2003	116.5813525	2192	111.5011508	2109	107.7708755	2058	106.2977424	1857	126.0698233	2325	0.986997615	0.008242061	normal	0.952301353	-0.260505016	normal	0.982772929	0.132289801	normal	0.895946735	-0.035603007	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K17294|3.62248e-165|pon:100439255|TSPAN4, tspan-4; tetraspanin 4; K17294 tetraspanin-4 (A)"	--	[R]	General function prediction only	Tetraspanin family	Tetraspanin-4 GN=TSPAN4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: tetraspanin-4 isoform 1 [Orcinus orca]
ENSG00000214078(CPNE1)	--	104.9695567	5398	96.98129109	5101	100.188519	5048	119.252479	5676	127.9886035	6518	101.1773793	4822	0.993728293	0.0416058	normal	0.945946209	0.332135394	normal	0.99253298	-0.074348909	normal	0.642153934	0.108664851	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Copine;; C2 domain	Copine-1 GN=CPNE1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	copine-1 [Sus scrofa] 
ENSG00000214087(ARL16)	--	22.35962799	346	19.17734895	302	21.4122837	357	32.300054	482	30.06332922	462	27.75393161	438	0.62023693	0.44574519	normal	0.178867044	0.589514431	normal	0.904785313	0.285621243	normal	0.039440503	0.438291704	normal	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family	ADP-ribosylation factor-like protein 16 GN=ARL16 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: ADP-ribosylation factor-like protein 16 [Ceratotherium simum simum]
ENSG00000214102(WEE2)	--	0	0	0	0	0	0	0	0	0	0	0.018203796	1	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K06632|0|hsa:494551|WEE2, WEE1B; WEE1 homolog 2 (S. pombe) (EC:2.7.10.2); K06632 wee1-like protein kinase [EC:2.7.11.1] (A)"	Cell cycle (ko04110)	[D]	"Cell cycle control, cell division, chromosome partitioning"	Protein kinase domain;; Protein tyrosine kinase	Wee1-like protein kinase 2 GN=WEE2 OS=Homo sapiens (Human) PE=2 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: wee1-like protein kinase 2 [Equus caballus]
ENSG00000214113(LYRM4)	--	41.63356	419	55.1857321	527	39.71783421	411	42.03189475	452	44.0079859	431	48.3584596	480	0.96759008	0.078263927	normal	0.882403874	-0.310554337	normal	0.942068407	0.214872297	normal	0.974574279	-0.014965147	normal	--	--	--	--	--	[A]	RNA processing and modification	Putative binding domain;; Complex1_LYR-like;; Complex 1 protein (LYR family)	LYR motif-containing protein 4 GN=LYRM4 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: LYR motif-containing protein 4 [Elephantulus edwardii]
ENSG00000214128(TMEM213)	--	0.0624759	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMEM213 family	Transmembrane protein 213 (Precursor) GN=TMEM213 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 213 [Pteropus alecto]
ENSG00000214160(ALG3)	--	38.367411	813	39.5897782	824	35.22454549	762	38.018587	813	38.040728	800	40.84634423	881	0.976755519	-0.030774106	normal	0.974936619	-0.06395177	normal	0.954719595	0.200688864	normal	0.909106449	0.034936189	normal	--	--	"Cellular Component: endoplasmic reticulum (GO:0005783);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring hexosyl groups (GO:0016758);; "	"K03845|0|mcf:102134126|ALG3; ALG3, alpha-1,3- mannosyltransferase; K03845 alpha-1,3-mannosyltransferase [EC:2.4.1.258] (A)"	N-Glycan biosynthesis (ko00510)	[G]	Carbohydrate transport and metabolism	ALG3 protein	"Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase GN=ALG3 OS=Homo sapiens (Human) PE=1 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase isoform X1 [Ochotona princeps]"
ENSG00000214193(SH3D21)	--	0.463629613	26	0.199038775	11	0.2813252	15	0.671197	38	0.3651014	22	0.175947554	10	0.965349141	0.492467391	normal	0.95471953	0.890626939	normal	--	--	--	0.765113825	0.403764941	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Variant SH3 domain;; Variant SH3 domain;; SH3 domain	SH3 domain-containing protein 21 GN=SH3D21 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: SH3 domain-containing protein 21 [Galeopterus variegatus]
ENSG00000214194(LINC00998)	--	48.9294	697	44.57782	637	41.27249	586	34.56546	502	34.39849	496	39.77337	570	0.357594479	-0.502990476	normal	0.774758373	-0.381350844	normal	0.972343243	-0.048104309	normal	0.119428571	-0.31321273	normal	--	--	--	--	--	--	--	--	Putative transmembrane protein LINC00998 (Precursor) GN=LINC00998 OS=Homo sapiens (Human) PE=5 SV=2	R	General function prediction only	hypothetical protein PANDA_003042 [Ailuropoda melanoleuca]
ENSG00000214212(C19orf38)	--	0.2253332	4	0.238084048	5	0.232511269	4	0	0	0.140383356	2	0.235750216	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein HIDE1 (Precursor) GN=HIDE1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein HIDE1 [Orycteropus afer afer]
ENSG00000214226(C17orf67)	--	4.844250587	324	5.69763272	391	5.275644906	369	6.11017131	453	5.8385282	438	6.451263814	505	0.613923289	0.45086947	normal	0.958987735	0.141817261	normal	0.622880284	0.442813735	normal	0.124549735	0.344065221	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4543)	Uncharacterized protein C17orf67 (Precursor) GN=C17orf67 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C17orf67 homolog [Vicugna pacos]
ENSG00000214253(FIS1)	--	55.329222	614	51.35119321	604	53.97166066	636	63.08446	740	60.04667084	667	55.443511	634	0.936722263	0.237911465	normal	0.966707772	0.121422274	normal	0.974318726	-0.012804872	normal	0.646315902	0.117041171	normal	--	--	--	K17969|9.62489e-43|ptr:740858|FIS1; fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae); K17969 mitochondrial fission 1 protein (A)	--	[M]	Cell wall/membrane/envelope biogenesis	Fis1 N-terminal tetratricopeptide repeat	Mitochondrial fission 1 protein GN=FIS1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial fission 1 protein isoform X1 [Bos taurus] 
ENSG00000214274(ANG)	--	10.19423479	268	4.153189873	112	6.068248876	168	9.623037223	238	12.888099	392	14.9098343	394	0.946364543	-0.200880666	normal	3.14E-14	1.772317533	up	2.99E-07	1.214094052	up	0.093776271	0.882253558	normal	--	--	--	"K16631|5.79768e-93|hsa:283|ANG, ALS9, HEL168, RAA1, RNASE4, RNASE5; angiogenin, ribonuclease, RNase A family, 5 (EC:3.1.27.-); K16631 angiogenin [EC:3.1.27.-] (A)"	--	--	--	Pancreatic ribonuclease	Angiogenin (Precursor) GN=ANG OS=Homo sapiens (Human) PE=1 SV=1	W	Extracellular structures	PREDICTED: angiogenin [Felis catus]
ENSG00000214279(SCART1)	--	0.123564	9	0.315077	24	0.116627	8	0.02719	2	0.0399644	2	0.0544474	4	--	--	--	0.010026395	-2.876894469	normal	--	--	--	--	--	--	--	--	Molecular Function: scavenger receptor activity (GO:0005044);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Scavenger receptor cysteine-rich domain;; Scavenger receptor cysteine-rich domain	Scavenger receptor cysteine-rich domain-containing protein SCART1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: putative scavenger receptor cysteine-rich domain-containing protein LOC619207-like [Odobenus rosmarus divergens]
ENSG00000214290(COLCA2)	--	1.221033198	22	1.373520328	33	1.098790257	24	0.604903344	13	1.284708296	31	1.53300011	36	0.971576593	-0.723417713	normal	0.982537068	-0.106583848	normal	0.960923251	0.548292407	normal	1	-0.000608644	normal	--	--	--	--	--	--	--	"POU domain, class 2, associating factor 1"	Colorectal cancer-associated protein 2 GN=COLCA2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C11orf93 homolog [Ceratotherium simum simum]
ENSG00000214300(SPDYE3)	--	0.611381	36	0.768084	46	0.872465	52	0.487198	29	0.31353	18	0.606758	36	0.977326665	-0.327185277	normal	0.215769911	-1.304173084	normal	0.93870497	-0.520514102	normal	0.22696857	-0.711328387	normal	--	--	--	--	--	--	--	Cell cycle regulatory protein;; Protein of unknown function (DUF3263);; VPR/VPX protein	Speedy protein E3 GN=SPDYE3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: speedy protein E4-like [Ursus maritimus]
ENSG00000214309(MBLAC1)	--	1.354132045	34	1.466070069	39	2.61734055	71	1.701608	41	2.42571178	51	1.650196	40	0.978803741	0.229791	normal	0.96412286	0.353577372	normal	0.601966049	-0.812740996	normal	0.868616564	-0.145401152	normal	--	--	--	--	--	[S]	Function unknown	Metallo-beta-lactamase superfamily	Metallo-beta-lactamase domain-containing protein 1 GN=MBLAC1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: metallo-beta-lactamase domain-containing protein 1 [Vicugna pacos]
ENSG00000214357(NEURL1B)	--	3.10599538	334	2.703212474	216	3.5424191	317	3.504030007	380	3.291204065	316	3.118735025	284	0.956527626	0.154651785	normal	0.474622907	0.524414469	normal	0.953972923	-0.166045993	normal	0.698446637	0.154988385	normal	--	--	--	"K01931|0|hsa:54492|NEURL1B, NEURL3, hNeur2, neur2; neuralized E3 ubiquitin protein ligase 1B (EC:6.3.2.-); K01931 protein neuralized [EC:6.3.2.19] (A)"	--	[T]	Signal transduction mechanisms	"Neuralized;; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase NEURL1B GN=NEURL1B OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase NEURL1B [Leptonychotes weddellii]
ENSG00000214376(VSTM5)	--	0	0	0.0188052	1	0	0	0.0189792	1	0.0371386	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin V-set domain	V-set and transmembrane domain-containing protein 5 (Precursor) GN=VSTM5 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: V-set and transmembrane domain-containing protein 5 [Lipotes vexillifer]
ENSG00000214413(BBIP1)	--	18.9932996	406	24.9239885	470	24.246346	484	16.99396334	336	16.544257	330	21.087799	424	0.891805158	-0.302589746	normal	0.347194133	-0.529576347	normal	0.947630927	-0.19857081	normal	0.1308599	-0.339639708	normal	--	--	--	--	--	--	--	--	BBSome-interacting protein 1 GN=BBIP1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	"BBSome-interacting protein 1, partial [Myotis brandtii]"
ENSG00000214435(AS3MT)	--	8.425755	283	10.446742	356	8.971624	316	6.17758351	227	6.015418	235	5.065484	179	0.864610743	-0.346834538	normal	0.166664329	-0.617390425	normal	0.007221506	-0.82295234	normal	0.01076264	-0.597040763	normal	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Cellular Component: nucleolus (GO:0005730);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	"K07755|0|hsa:57412|AS3MT, CYT19; arsenite methyltransferase (EC:2.1.1.137); K07755 arsenite methyltransferase [EC:2.1.1.137] (A)"	--	--	--	Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);; Hypothetical methyltransferase	Arsenite methyltransferase GN=AS3MT OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: arsenite methyltransferase [Equus caballus] 
ENSG00000214456(PLIN5)	--	0.0203651	1	0.0195833	1	0	0	0	0	0.0396059	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Perilipin family	Perilipin-5 GN=PLIN5 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: perilipin-5 [Galeopterus variegatus]
ENSG00000214510(SPINK13)	--	0.127495475	1	0	0	0	0	0.0617788	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Kazal-type serine protease inhibitor domain;; Kazal-type serine protease inhibitor domain	Serine protease inhibitor Kazal-type 13 (Precursor) GN=SPINK13 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: serine protease inhibitor Kazal-type 13 [Camelus ferus] 
ENSG00000214513(NOTO)	--	0	0	0	0	0	0	0	0	0.0203387	0	0.0207458	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	Homeobox domain	Homeobox protein notochord GN=NOTO OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: homeobox protein notochord [Galeopterus variegatus]
ENSG00000214517(PPME1)	--	27.358647	1347	26.45669	1313	32.746529	1614	31.364403	1550	27.440888	1340	29.568313	1456	0.97155841	0.171503635	normal	0.982306455	0.007930485	normal	0.974988294	-0.156766937	normal	0.996314771	0.003024215	normal	[R]	General function prediction only	--	"K13617|0|hsa:51400|PPME1, PME-1; protein phosphatase methylesterase 1 (EC:3.1.1.89); K13617 protein phosphatase methylesterase 1 [EC:3.1.1.89] (A)"	--	[R]	General function prediction only	Alpha/beta hydrolase family;; Alpha/beta hydrolase family;; alpha/beta hydrolase fold	Protein phosphatase methylesterase 1 GN=PPME1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: protein phosphatase methylesterase 1 isoform X1 [Lipotes vexillifer]
ENSG00000214534(ZNF705E)	--	0.0318745	2	0.0161136	1	0.0802677	4	0.111088	7	0.0154583	0	0.126185	8	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:100131539|ZNF705E; zinc finger protein 705E; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; KRAB box;; Zinc finger, C2H2 type"	Putative zinc finger protein 705E GN=ZNF705E OS=Homo sapiens (Human) PE=3 SV=1	K	Transcription	PREDICTED: zinc finger protein 596-like [Lipotes vexillifer]
ENSG00000214562(NUTM2D)	--	1.4180831	145	0.946199	113	1.510949801	110	1.518783	154	1.7711384	188	1.286096	168	0.966973597	0.055474786	normal	0.197899609	0.705589384	normal	0.522284658	0.595988927	normal	0.190070851	0.449715127	normal	--	--	--	--	--	--	--	NUT protein N terminus;; NUT protein C terminal	NUT family member 2D GN=NUTM2D OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	PREDICTED: NUT family member 2G-like [Equus caballus]
ENSG00000214595(EML6)	--	1.017743851	78	0.82550314	116	0.673292838	77	0.31274318	43	0.675249751	78	0.503920737	65	0.419836378	-0.866631888	normal	0.712202368	-0.58464681	normal	0.963112806	-0.247414895	normal	0.221316865	-0.563382921	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K18598|0|hsa:400954|EML6; echinoderm microtubule associated protein like 6; K18598 echinoderm microtubule-associated protein-like 6 (A)	--	[S]	Function unknown	"WD domain, G-beta repeat;; HELP motif;; Nup133 N terminal like"	Echinoderm microtubule-associated protein-like 6 GN=EML6 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: echinoderm microtubule-associated protein-like 6, partial [Tupaia chinensis]"
ENSG00000214652(ZNF727)	--	0.067668	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:442319|ZNF727, ZNF727P; zinc finger protein 727; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; C1-like domain"	Putative zinc finger protein 727 GN=ZNF727 OS=Homo sapiens (Human) PE=5 SV=3	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000214654(RP11-27I1.4)	--	3.271785	195	3.288086	178	3.267324	187	2.491644	145	1.7562356	103	3.258191	167	0.771678312	-0.454087372	normal	0.073441791	-0.801591307	normal	0.955722848	-0.170025749	normal	0.162340569	-0.453180927	normal	--	--	"Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K03766|0|mcf:102129749|putative UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase LOC402377-like; K03766 beta-1,3-N-acetylglucosaminyltransferase 5 [EC:2.4.1.206] (A)"	Glycosphingolipid biosynthesis - lacto and neolacto series (ko00601)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase;; Fringe-like	"Putative UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase LOC100288842 OS=Homo sapiens (Human) PE=5 SV=2"	G	Carbohydrate transport and metabolism	"PREDICTED: putative UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase LOC402377-like [Leptonychotes weddellii]"
ENSG00000214655(ZSWIM8)	--	14.41280949	1301	14.27998876	1328	16.51914973	1290	10.31466364	1163	11.62918584	1200	16.51309581	1663	0.964273305	-0.192361685	normal	0.969851217	-0.167446596	normal	0.838836157	0.35775533	normal	0.971889593	0.018698169	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	[S]	Function unknown	--	Zinc finger SWIM domain-containing protein 8 GN=ZSWIM8 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: zinc finger SWIM domain-containing protein 8 isoform 2 [Orcinus orca]
ENSG00000214688(C10orf105)	--	0.099058662	9	0	0	0	0	0.011102719	1	0.02146502	1	0.032741091	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C10orf105 GN=C10orf105 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C10orf105 homolog [Galeopterus variegatus]
ENSG00000214694(ARHGEF33)	--	0.06490884	4	0.016229642	1	0.071780354	5	0.129474034	10	0.015661979	0	0.023963909	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	--	--	RhoGEF domain	Rho guanine nucleotide exchange factor 33 GN=ARHGEF33 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 33 [Odobenus rosmarus divergens]
ENSG00000214711(CAPN14)	--	0.077570647	4	0.153157175	8	0.075607241	3	0	0	0.042399495	1	0.10786471	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium-dependent cysteine-type endopeptidase activity (GO:0004198);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	K13442|0|hsa:440854|CAPN14; calpain 14 (EC:3.4.22.-); K13442 calpain-14 [EC:3.4.22.-] (A)	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	"Calpain family cysteine protease;; Calpain large subunit, domain III"	Calpain-14 GN=CAPN14 OS=Homo sapiens (Human) PE=2 SV=2	OT	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	PREDICTED: calpain-14 [Ursus maritimus]
ENSG00000214736(TOMM6)	--	180.4238	1115	196.1799	1236	180.4409	1148	201.9608	1322	176.2887	1083	185.1664	1184	0.957632945	0.214574417	normal	0.957582635	-0.211794978	normal	0.980904185	0.036208029	normal	0.964587023	0.014967473	normal	--	--	--	K17772|3.48267e-46|ptr:748580|TOMM6; translocase of outer mitochondrial membrane 6 homolog (yeast); K17772 mitochondrial import receptor subunit TOM6 (A)	--	--	--	Mitochondrial import receptor subunit TOM6 homolog	Mitochondrial import receptor subunit TOM6 homolog GN=TOMM6 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import receptor subunit TOM6 homolog [Ceratotherium simum simum]
ENSG00000214756(METTL12)	--	1.76427	59	2.16804	74	1.33598	45	2.51398	85	2.80037	93	1.71666	58	0.898579511	0.485336383	normal	0.947668683	0.302749893	normal	0.96153444	0.347524372	normal	0.469899753	0.384110692	normal	--	--	Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[E]	Amino acid transport and metabolism	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain	"Methyltransferase-like protein 12, mitochondrial (Precursor) GN=METTL12 OS=Homo sapiens (Human) PE=2 SV=1"	R	General function prediction only	"PREDICTED: methyltransferase-like protein 12, mitochondrial [Galeopterus variegatus]"
ENSG00000214776(RP11-726G1.1)	--	0.704139428	37	1.143921889	63	0.690658992	49	0.493642126	30	0.245464304	19	0.929256714	39	0.977075999	-0.318669802	normal	0.001949272	-1.673471242	down	0.968999267	-0.326287392	normal	0.159502896	-0.780393024	normal	--	--	Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular space (GO:0005615);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; Alpha-2-macroglobulin family N-terminal region;; Alpha-2-macroglobulin family;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region	Ovostatin homolog 2 (Precursor) GN=OVOS2 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ovostatin homolog 2 [Equus przewalskii]
ENSG00000214814(FER1L6)	--	0	0	0.0136958	2	0.0135688	1	0	0	0.0467456	6	0.00682298	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	C2 domain;; FerB (NUC096) domain;; FerI (NUC094) domain	Fer-1-like protein 6 GN=FER1L6 OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: fer-1-like protein 6 [Myotis lucifugus]
ENSG00000214872(SMTNL1)	--	0.067100523	3	0.043582	2	0.085277032	3	0	0	0.087155433	3	0.044229199	2	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Calponin homology (CH) domain;; CAMSAP CH domain	Smoothelin-like protein 1 GN=SMTNL1 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: smoothelin-like protein 1 [Galeopterus variegatus]
ENSG00000214940(NPIPA8)	--	0.361127435	6	0.175586245	3	1.102241409	18	0.23175919	4	0.175752967	2	0.649642065	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A8 GN=NPIPA8 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	--
ENSG00000214941(ZSWIM7)	--	20.1391209	316	23.15893	348	19.73811	301	15.219094	243	14.628088	221	17.861379	284	0.769627313	-0.407533455	normal	0.079447049	-0.672765558	normal	0.964037721	-0.091689666	normal	0.123099924	-0.388451028	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	SWIM zinc finger	Zinc finger SWIM domain-containing protein 7 GN=ZSWIM7 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: zinc finger SWIM domain-containing protein 7 [Tupaia chinensis]
ENSG00000214944(ARHGEF28)	--	15.28362084	1714	16.98406705	1784	15.06393304	1728	14.72063904	1760	11.55668551	1331	15.40234596	1820	0.985516993	0.007369537	normal	0.604911622	-0.443594551	normal	0.984484926	0.066487088	normal	0.639024034	-0.110932437	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; Phorbol esters/diacylglycerol binding domain (C1 domain);; PH domain	Rho guanine nucleotide exchange factor 28 GN=ARHGEF28 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: rho guanine nucleotide exchange factor 28 [Pteropus alecto]
ENSG00000214946(TBC1D26)	--	0.0537128	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	--	--	Rab-GTPase-TBC domain	TBC1 domain family member 26 GN=TBC1D26 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: TBC1 domain family member 26-like isoform X3 [Oryctolagus cuniculus]
ENSG00000214960(ISPD)	--	0.193023598	16	0.528469945	44	0.55599066	39	0.595864674	42	0.5847696	42	0.699077348	38	0.364332574	1.282928541	normal	0.978973337	-0.08553148	normal	0.981832015	-0.04403619	normal	0.721029296	0.280230079	normal	[I]	Lipid transport and metabolism	Molecular Function: cytidylyltransferase activity (GO:0070567);; 	--	--	--	--	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase;; MobA-like NTP transferase domain	Isoprenoid synthase domain-containing protein GN=ISPD OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: isoprenoid synthase domain-containing protein isoform 1 [Orcinus orca]
ENSG00000214967(NPIPA7)	--	0.888299205	22	0.647849635	16	0.802697062	19	0.64257322	16	0.509928217	12	0.923427783	23	0.983517687	-0.453014938	normal	--	--	--	0.986459969	0.249286707	normal	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A8 GN=NPIPA8 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	--
ENSG00000215018(COL28A1)	--	0.294027324	5	0.151946801	4	0.091296413	3	0.76667448	56	1.406476221	106	0.906557453	70	1.03E-07	3.111098664	up	0	4.267372194	up	1.93E-12	3.979446252	up	5.88E-09	4.252045081	up	--	--	Molecular Function: serine-type endopeptidase inhibitor activity (GO:0004867);; 	--	--	[T]	Signal transduction mechanisms	Collagen triple helix repeat (20 copies);; von Willebrand factor type A domain;; von Willebrand factor type A domain;; Kunitz/Bovine pancreatic trypsin inhibitor domain;; von Willebrand factor type A domain	Collagen alpha-1(XXVIII) chain (Precursor) GN=COL28A1 OS=Homo sapiens (Human) PE=2 SV=2	W	Extracellular structures	PREDICTED: collagen alpha-1(XXVIII) chain [Galeopterus variegatus] 
ENSG00000215021(PHB2)	--	115.7281451	3103	101.721654	2798	105.067856	2827	142.1617963	3918	148.3086941	4051	126.3807306	3437	0.943679699	0.305486578	normal	0.374264601	0.512224275	normal	0.957762205	0.27345366	normal	0.01979436	0.36449369	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K17081|0|ptr:451805|PHB2; prohibitin 2; K17081 prohibitin 2 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	SPFH domain / Band 7 family	Prohibitin-2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: prohibitin-2 [Galeopterus variegatus]
ENSG00000215029(TCP11X2)	--	0	0	0	0	0	0	0	0	0	0	0.0305972	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[T]	Signal transduction mechanisms	T-complex protein 11	T-complex protein 11 X-linked protein 2 GN=TCP11X2 OS=Homo sapiens (Human) PE=3 SV=1	T	Signal transduction mechanisms	PREDICTED: T-complex protein 11 homolog isoform X2 [Ursus maritimus]
ENSG00000215041(NEURL4)	--	9.49671535	1046	8.99300713	1028	9.589394923	1072	8.770067943	976	8.99369169	994	10.54833245	1168	0.97239996	-0.130563461	normal	0.977365217	-0.069844567	normal	0.975660015	0.115288074	normal	0.938207766	-0.024270901	normal	--	--	--	K16777|0|pps:100980246|NEURL4; neuralized E3 ubiquitin protein ligase 4; K16777 neuralized-like protein 4 (A)	--	[T]	Signal transduction mechanisms	Neuralized	Neuralized-like protein 4 GN=NEURL4 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	"Neuralized-like protein 4, partial [Bos mutus]"
ENSG00000215045(GRID2IP)	--	0.03142105	2	0.031574063	2	0.030353029	1	0	0	0.015207639	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[S]	Function unknown	Formin Homology 2 Domain;; PDZ domain (Also known as DHR or GLGF);; PDZ domain	Delphilin GN=GRID2IP OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: delphilin [Galeopterus variegatus]
ENSG00000215114(UBXN2B)	--	14.467057	928	13.54049546	928	12.15502334	921	12.71506554	931	11.748161	843	12.8406137	905	0.97844003	-0.026132705	normal	0.965472556	-0.159745466	normal	0.978135842	-0.033519282	normal	0.781587836	-0.073161467	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[Y]	Nuclear structure	SEP domain;; UBX domain	UBX domain-containing protein 2B GN=UBXN2B OS=Homo sapiens (Human) PE=1 SV=1	Y	Nuclear structure	PREDICTED: UBX domain-containing protein 2B [Canis lupus familiaris]
ENSG00000215126(CBWD7)	--	2.905456197	60	2.809937439	59	2.251728328	53	2.370626221	57	2.150102456	49	2.269315978	53	0.975890757	-0.102148661	normal	0.965527339	-0.281431827	normal	0.978086032	-0.00806142	normal	0.866978052	-0.135052563	normal	[R]	General function prediction only	--	--	--	[H]	Coenzyme transport and metabolism	"CobW/HypB/UreG, nucleotide-binding domain;; Cobalamin synthesis protein cobW C-terminal domain;; Elongation factor Tu GTP binding domain"	COBW domain-containing protein 6 GN=CBWD6 OS=Homo sapiens (Human) PE=2 SV=1	H	Coenzyme transport and metabolism	PREDICTED: COBW domain-containing protein 2 isoform X1 [Equus przewalskii]
ENSG00000215182(MUC5AC)	--	0.034398311	15	0.038142098	14	0.055030416	21	0.827513	332	0.82298935	350	0.405619542	178	0	4.304792285	up	0	4.481755859	up	0	2.987319976	up	5.09E-10	4.082385529	up	--	--	--	--	--	[WV]	Extracellular structures;; Defense mechanisms	Mucin-2 protein WxxW repeating region;; von Willebrand factor type D domain;; C8 domain;; Trypsin Inhibitor like cysteine rich domain;; von Willebrand factor type C domain	Mucin-5AC (Precursor; Fragments) GN=MUC5AC OS=Homo sapiens (Human) PE=1 SV=3	VW	Defense mechanisms;; Extracellular structures	PREDICTED: LOW QUALITY PROTEIN: mucin-5AC [Equus caballus]
ENSG00000215183(MSMP)	--	2.32367	21	1.93913	18	2.44687	22	3.67947	34	2.5912	23	1.63842	15	0.956370502	0.627924066	normal	0.984843295	0.30918695	normal	0.981168735	-0.517520013	normal	0.835719276	0.21580197	normal	--	--	--	--	--	--	--	Beta-microseminoprotein (PSP-94)	Prostate-associated microseminoprotein (Precursor) GN=MSMP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: prostate-associated microseminoprotein [Ceratotherium simum simum]
ENSG00000215186(GOLGA6B)	--	0.0352476	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Putative golgin subfamily A member 6B GN=GOLGA6B OS=Homo sapiens (Human) PE=5 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X2 [Galeopterus variegatus]
ENSG00000215187(FAM166B)	--	0.201879	3	0.2521811	4	0.2436991	3	0.265969	4	0	0	0.1826388	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF2475)	Protein FAM166B GN=FAM166B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	uncharacterized protein LOC100156839 [Sus scrofa]
ENSG00000215193(PEX26)	--	8.525992715	586	8.770498993	726	8.7042778	651	11.13540725	812	10.47874109	730	13.0072204	883	0.593471507	0.438765773	normal	0.97522702	-0.013471658	normal	0.620347453	0.430602369	normal	0.13900041	0.283877448	normal	--	--	Cellular Component: integral component of peroxisomal membrane (GO:0005779);; Molecular Function: protein complex binding (GO:0032403);; Biological Process: protein import into peroxisome membrane (GO:0045046);; 	"K13340|0|hsa:55670|PEX26, PBD7A, PBD7B, PEX26M1T, Pex26pM1T; peroxisomal biogenesis factor 26; K13340 peroxin-26 (A)"	Peroxisome (ko04146)	--	--	Pex26 protein	Peroxisome assembly protein 26 GN=PEX26 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: peroxisome assembly protein 26 isoform 1 [Trichechus manatus latirostris]
ENSG00000215217(C5orf49)	--	0.242893024	10	0.16685401	7	0.0708863	2	0.256073516	8	0.192952889	5	0.346937198	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4541)	Uncharacterized protein C5orf49 GN=C5orf49 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C5orf49 homolog [Equus przewalskii]
ENSG00000215218(UBE2QL1)	--	0.0777846	6	0.0898698	7	0.0762455	5	0.0388	3	0.16327	12	0.102665	8	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K10582|8.20674e-119|ssc:100518586|ubiquitin-conjugating enzyme E2Q-like protein CG4502-like; K10582 ubiquitin-conjugating enzyme E2 Q [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme	Ubiquitin-conjugating enzyme E2Q-like protein 1 GN=UBE2QL1 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2Q-like protein CG4502-like [Sus scrofa]
ENSG00000215252(GOLGA8B)	--	13.621216	654	13.678262	666	11.6710768	564	14.499309	703	16.45958	789	17.382785	840	0.972689483	0.073235829	normal	0.944650422	0.222611701	normal	0.145287037	0.56515306	normal	0.13881962	0.286856317	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5;; Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8A GN=GOLGA8A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	"golgi autoantigen, golgin subfamily a, 2 isoform 1 [Camelus ferus]"
ENSG00000215262(KCNU1)	--	0	0	0	0	0	0	0.130779044	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Biological Process: potassium ion transport (GO:0006813);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K05274|0|hsa:157855|KCNU1, KCNMC1, KCa5, KCa5.1, Kcnma3, Slo3; potassium channel, subfamily U, member 1; K05274 potassium large conductance calcium-activated channel subfamily M alpha member 3 (A)"	cGMP-PKG signaling pathway (ko04022);; Vascular smooth muscle contraction (ko04270);; Insulin secretion (ko04911)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Calcium-activated BK potassium channel alpha subunit;; Ion transport protein;; Ion channel	Potassium channel subfamily U member 1 GN=KCNU1 OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: potassium channel subfamily U member 1 [Ceratotherium simum simum]
ENSG00000215271(HOMEZ)	--	7.0478568	440	7.393703269	478	7.093850329	422	5.015761455	345	4.3929416	317	6.513652654	433	0.788397062	-0.380235677	normal	0.123074313	-0.611560657	normal	0.969998095	0.028730938	normal	0.175340965	-0.312014433	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	"Homeodomain leucine-zipper encoding, Homez;; Homeobox domain;; Homeobox KN domain"	Homeobox and leucine zipper protein Homez GN=HOMEZ OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: homeobox and leucine zipper protein Homez isoform X2 [Panthera tigris altaica]
ENSG00000215301(DDX3X)	--	124.2302513	9947	129.0767804	10317	109.9832225	8660	143.405581	11589	155.0502909	12108	129.4849791	10391	0.99249158	0.189563293	normal	0.991271884	0.209482132	normal	0.984691592	0.254563494	normal	0.282815483	0.215257839	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: ATP binding (GO:0005524);; 	"K11594|0|cfa:480886|DDX3X; DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked; K11594 ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] (A)"	RIG-I-like receptor signaling pathway (ko04622);; Hepatitis B (ko05161);; Viral carcinogenesis (ko05203)	[A]	RNA processing and modification	DEAD/DEAH box helicase;; Helicase conserved C-terminal domain	ATP-dependent RNA helicase DDX3X GN=DDX3X OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: ATP-dependent RNA helicase DDX3X isoform X12 [Canis lupus familiaris]
ENSG00000215375(MYL5)	--	4.78751	138	5.157439375	137	3.809983442	100	4.670682147	108	6.42417635	127	4.699053228	130	0.897722835	-0.37967721	normal	0.962101464	-0.129291179	normal	0.91122583	0.36536122	normal	0.923805752	-0.060128693	normal	[TZDR]	"Signal transduction mechanisms;; Cytoskeleton;; Cell cycle control, cell division, chromosome partitioning;; General function prediction only"	Molecular Function: calcium ion binding (GO:0005509);; 	"K12753|5.44703e-122|hsa:4636|MYL5; myosin, light chain 5, regulatory; K12753 myosin regulatory light chain 5 (A)"	Focal adhesion (ko04510);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810)	[Z]	Cytoskeleton	EF hand;; EF-hand domain pair;; EF-hand domain;; EF-hand domain pair;; EF hand	Myosin light chain 5 GN=MYL5 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	Myosin light chain 5 [Tupaia chinensis]
ENSG00000215397(SCRT2)	--	118.9760055	5903	128.4210052	6535	110.9936945	5611	83.33380554	4162	85.2813044	4211	83.29697709	4158	0.282508718	-0.534836908	normal	0.026368375	-0.655260395	normal	0.722920139	-0.440521137	normal	0.000224325	-0.547801665	normal	[R]	General function prediction only	--	"K09219|4.26467e-156|hsa:85508|SCRT2, ZNF898B; scratch family zinc finger 2; K09219 scratch (A)"	--	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Transcriptional repressor scratch 2 GN=SCRT2 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	"PREDICTED: transcriptional repressor scratch 2, partial [Dasypus novemcinctus]"
ENSG00000215421(ZNF407)	--	1.81894575	302	1.838824141	299	1.6410641	280	1.794902421	308	1.8027215	309	1.993307542	339	0.967882209	-0.00243818	normal	0.966643184	0.025905908	normal	0.91976337	0.266258204	normal	0.789837648	0.096835822	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; C2H2-type zinc-finger domain;; Zinc finger, C2H2 type"	Zinc finger protein 407 GN=ZNF407 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 407 [Ceratotherium simum simum]
ENSG00000215440(NPEPL1)	--	19.3093465	878	21.34740657	1006	20.94511307	974	18.2657305	837	18.6208701	842	20.74348012	931	0.973543637	-0.099646955	normal	0.919996741	-0.277707714	normal	0.976951478	-0.073315601	normal	0.485739364	-0.151802687	normal	[E]	Amino acid transport and metabolism	Molecular Function: aminopeptidase activity (GO:0004177);; Cellular Component: intracellular (GO:0005622);; Biological Process: proteolysis (GO:0006508);; 	K09611|0|ptr:469985|NPEPL1; aminopeptidase-like 1; K09611 probable aminopeptidase NPEPL1 [EC:3.4.11.-] (A)	--	[R]	General function prediction only	"Cytosol aminopeptidase family, catalytic domain"	Probable aminopeptidase NPEPL1 GN=NPEPL1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: probable aminopeptidase NPEPL1 [Odobenus rosmarus divergens]
ENSG00000215612(HMX1)	--	0.22988372	6	0.291989041	8	0.10449	2	0.333478425	9	0.218848	5	0.630354415	17	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09349|8.51555e-83|hsa:3166|HMX1, H6, NKX5-3; H6 family homeobox 1; K09349 homeobox protein Nkx-5 (A)"	--	[K]	Transcription	Homeobox domain	Homeobox protein HMX1 GN=HMX1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: uncharacterized protein LOC101401941 [Ceratotherium simum simum]
ENSG00000215712(TMEM242)	--	14.00552705	225	11.95742454	221	9.454306141	208	14.758366	229	16.85545026	258	12.3253381	243	0.966987481	-0.005373297	normal	0.945645844	0.200626524	normal	0.943829236	0.214636231	normal	0.718350231	0.137522755	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1358)	Transmembrane protein 242 GN=TMEM242 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 242 [Canis lupus familiaris]
ENSG00000215717(TMEM167B)	--	8.14429	370	5.223862115	262	6.609981145	307	10.10073	460	9.78484356	483	8.30565274	389	0.906586604	0.282223619	normal	0.001096194	0.857331375	normal	0.865800786	0.331784926	normal	0.022890773	0.482810317	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF1242)	Protein kish-B (Precursor) GN=TMEM167B OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	protein kish-B precursor [Bos taurus] 
ENSG00000215784(FAM72D)	--	2.07588	81	2.31426	92	2.53317	99	1.91915	76	1.13897	44	1.38938	55	0.97102249	-0.120396488	normal	0.057558892	-1.059797167	normal	0.290284079	-0.838853504	normal	0.131493897	-0.658499015	normal	--	--	--	--	--	--	--	FAM72 protein	Protein FAM72D GN=FAM72D OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM72A [Canis lupus familiaris]
ENSG00000215790(SLC35E2)	--	6.566677	145	5.366205	125	4.645512	108	5.371676	120	5.989883	132	6.728741	148	0.930562522	-0.300346198	normal	0.966560119	0.056517859	normal	0.843196798	0.44097904	normal	0.921103549	0.060713122	normal	--	--	--	--	--	[GE]	Carbohydrate transport and metabolism;; Amino acid transport and metabolism	EamA-like transporter family	Solute carrier family 35 member E2 GN=SLC35E2 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	hypothetical protein PANDA_013770 [Ailuropoda melanoleuca]
ENSG00000215817(ZC3H11B)	--	0.043891133	4	0.044071409	4	0.054528721	4	0.08765386	8	0.053387895	4	0.04361758	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	Zinc finger CCCH domain-containing protein 11A GN=ZC3H11A OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: zinc finger CCCH domain-containing protein 11A [Galeopterus variegatus]
ENSG00000215845(TSTD1)	--	0	0	0.439207	3	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	--	--	--	[P]	Inorganic ion transport and metabolism	Rhodanese-like domain	Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 GN=TSTD1 OS=Homo sapiens (Human) PE=1 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 1 [Tupaia chinensis] 
ENSG00000215853(RPTN)	--	0.00944939	1	0	0	0.0094645	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	S-100/ICaBP type calcium binding domain	Repetin GN=RPTN OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: repetin [Ursus maritimus]
ENSG00000215883(CYB5RL)	--	2.861232358	280	5.111532249	360	5.068597623	392	3.624922222	258	2.050657854	221	3.65094099	308	0.957028648	-0.148041408	normal	0.033738045	-0.721468604	normal	0.837324247	-0.354667253	normal	0.136926856	-0.41140153	normal	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[HC]	Coenzyme transport and metabolism;; Energy production and conversion	"Oxidoreductase FAD-binding domain;; Oxidoreductase-like protein, N-terminal;; Oxidoreductase NAD-binding domain"	NADH-cytochrome b5 reductase-like GN=CYB5RL OS=Homo sapiens (Human) PE=1 SV=3	CH	Energy production and conversion;; Coenzyme transport and metabolism	PREDICTED: NADH-cytochrome b5 reductase-like [Galeopterus variegatus]
ENSG00000215912(TTC34)	--	0.07561118	13	0.063563	11	0.118354016	20	0.0529107	9	0.079098323	13	0.057424067	10	--	--	--	--	--	--	0.961787956	-0.909441835	normal	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: identical protein binding (GO:0042802);; 	--	--	--	--	"TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Anaphase-promoting complex, cyclosome, subunit 3;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat"	Tetratricopeptide repeat protein 34 GN=TTC34 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: tetratricopeptide repeat protein 34 [Orcinus orca]
ENSG00000215915(ATAD3C)	--	0.039460638	3	0.049771431	3	0.0251581	1	0.026105894	2	0.016574439	0	0.033648487	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ATP binding (GO:0005524);; Biological Process: DNA repair (GO:0006281);; Biological Process: DNA recombination (GO:0006310);; Molecular Function: four-way junction helicase activity (GO:0009378);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Domain of unknown function (DUF3523);; ATPase family associated with various cellular activities (AAA);; AAA domain;; Zonular occludens toxin (Zot);; Holliday junction DNA helicase ruvB N-terminus	ATPase family AAA domain-containing protein 3C GN=ATAD3C OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ATPase family AAA domain-containing protein 3-like isoform X4 [Mustela putorius furo] 
ENSG00000216490(IFI30)	--	18.1262167	233	15.08526148	261	7.642472237	136	15.9367181	207	14.12973124	227	14.0185894	225	0.947713388	-0.200130252	normal	0.939691371	-0.22140715	normal	0.11654346	0.711810601	normal	0.9508736	0.043043748	normal	--	--	--	"K08059|1.48147e-172|hsa:10437|IFI30, GILT, IFI-30, IP-30, IP30; interferon, gamma-inducible protein 30; K08059 interferon, gamma-inducible protein 30 (A)"	Antigen processing and presentation (ko04612)	[O]	"Posttranslational modification, protein turnover, chaperones"	Gamma interferon inducible lysosomal thiol reductase (GILT)	Gamma-interferon-inducible lysosomal thiol reductase (Precursor) GN=IFI30 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: gamma-interferon-inducible-lysosomal thiol reductase-like [Mustela putorius furo]
ENSG00000216588(IGSF23)	--	0.296251896	2	0	0	0	0	0.164423313	2	0	0	0.235262361	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Immunoglobulin domain	Immunoglobulin superfamily member 23 GN=IGSF23 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: uncharacterized protein LOC612360 [Canis lupus familiaris]
ENSG00000216921(AC131097.4)	--	0	0	0.184651628	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	"hypothetical protein M91_12507, partial [Bos mutus]"
ENSG00000216937(CCDC7)	--	1.587919001	34	1.13924064	20	2.263313145	57	0.899781593	23	0.73330637	19	1.170587542	28	0.9625191	-0.563573082	normal	0.988135588	-0.088556171	normal	0.470132595	-0.995395713	normal	0.435584475	-0.684270135	normal	--	--	--	--	--	--	--	Spermatogenesis family BioT2	Uncharacterized protein C10orf68 GN=C10orf68 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 7 isoform X1 [Canis lupus familiaris]
ENSG00000217236(SP9)	--	7.602133	326	4.91387	232	5.021979178	235	3.351777776	145	4.5538418	195	3.062576019	130	1.83E-06	-1.190994053	down	0.923856334	-0.270153673	normal	0.012151959	-0.854934794	normal	0.015039885	-0.776177804	normal	[R]	General function prediction only	--	K09199|0|mcf:102147150|SP9; Sp9 transcription factor; K09199 transcription factor Sp9 (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Transcription factor Sp9 GN=SP9 OS=Homo sapiens (Human) PE=3 SV=1	K	Transcription	PREDICTED: transcription factor Sp9 [Bison bison bison]
ENSG00000217442(SYCE3)	--	0.487239	2	0	0	0.224353	0	0.443222	2	0.477434	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Synaptonemal complex central element protein 3	Synaptonemal complex central element protein 3 GN=SYCE3 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: synaptonemal complex central element protein 3 [Trichechus manatus latirostris]
ENSG00000218336(TENM3)	--	6.22722713	694	4.5107632	492	9.180293342	739	9.079744506	1130	10.33491526	1352	12.65736062	1407	0.014315816	0.67130773	normal	6.45E-14	1.43416831	up	1.12E-05	0.919298044	normal	4.54E-07	0.994514365	normal	--	--	Biological Process: signal transduction (GO:0007165);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	Teneurin Intracellular Region;; GHH signature containing HNH/Endo VII superfamily nuclease toxin;; NHL repeat;; EGF-like domain;; RHS Repeat;; Human growth factor-like EGF	Teneurin-3 GN=TENM3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: teneurin-3 isoform 2 [Ceratotherium simum simum]
ENSG00000218739(CEBPZOS)	--	49.10564546	1664	49.35922841	1694	48.35063064	1648	40.04271928	1388	38.134063	1294	37.49239152	1278	0.922761665	-0.29218424	normal	0.722043498	-0.409603037	normal	0.803347351	-0.374728264	normal	0.022680936	-0.359648807	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC102149508 isoform X1 [Equus caballus] 
ENSG00000218823(PAPOLB)	--	0	0	0.014043	1	0.0140531	0	0	0	0	0	0.0139339	1	--	--	--	--	--	--	--	--	--	--	--	--	[A]	RNA processing and modification	Molecular Function: RNA binding (GO:0003723);; Molecular Function: polynucleotide adenylyltransferase activity (GO:0004652);; Molecular Function: nucleotidyltransferase activity (GO:0016779);; Biological Process: RNA polyadenylation (GO:0043631);; 	"K14376|0|hsa:56903|PAPOLB, PAPT, TPAP; poly(A) polymerase beta (testis specific) (EC:2.7.7.19); K14376 poly(A) polymerase [EC:2.7.7.19] (A)"	mRNA surveillance pathway (ko03015)	[A]	RNA processing and modification	Poly(A) polymerase central domain;; Poly(A) polymerase predicted RNA binding domain;; Nucleotidyltransferase domain	Poly(A) polymerase beta GN=PAPOLB OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: LOW QUALITY PROTEIN: poly(A) polymerase beta [Galeopterus variegatus]
ENSG00000218891(ZNF579)	--	15.36157783	826	15.05535742	826	17.49940587	947	17.11157461	839	16.0228702	840	17.96785392	827	0.977382851	-0.008287938	normal	0.976905786	0.002815876	normal	0.955228419	-0.203420634	normal	0.782273299	-0.073544537	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 579 GN=ZNF579 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 579 [Oryctolagus cuniculus]
ENSG00000219435(TEX40)	--	0.892290975	10	0.78147643	9	0.650021419	8	0.681022716	8	1.635587033	18	0.864483752	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testis-expressed sequence 40 protein GN=TEX40 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 40 protein isoform X2 [Tupaia chinensis]
ENSG00000219438(FAM19A5)	--	3.116915472	102	3.456114506	91	2.638427688	85	4.502437449	148	8.288079728	239	6.653178585	204	0.774088345	0.499913209	normal	7.89E-07	1.357209612	up	2.67E-05	1.240059219	up	0.001210859	1.067718888	up	--	--	--	--	--	--	--	TAFA family	Protein FAM19A5 GN=FAM19A5 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: protein FAM19A5 [Trichechus manatus latirostris]
ENSG00000219481(NBPF1)	--	3.265640635	428	2.871032	393	2.696973	377	3.566631	473	4.507590135	584	2.4404156	328	0.964533038	0.113011128	normal	0.249697608	0.548271388	normal	0.943432136	-0.208263722	normal	0.686778393	0.187179714	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220);; Ribonuclease 2-5A	Neuroblastoma breakpoint family member 1 GN=NBPF1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4-like isoform X1 [Bos taurus]
ENSG00000219545(UMAD1)	--	19.26429	498	17.69359	417	19.09746	463	14.037727	382	16.10192	394	14.999161	416	0.708923884	-0.411949326	normal	0.964000471	-0.102894348	normal	0.956588521	-0.162161031	normal	0.352020539	-0.230062602	normal	--	--	--	--	--	--	--	--	UBAP1-MVB12-associated (UMA)-domain containing protein 1 {ECO:0000312|HGNC:HGNC:48955} OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: UBAP1-MVB12-associated (UMA)-domain containing protein 1 isoform X1 [Bos taurus] 
ENSG00000219607(PPP1R3G)	--	0.964498	76	1.06371	86	0.849865	69	1.10528	88	1.16101	92	1.02397	82	0.966880073	0.17733812	normal	0.969584281	0.074602175	normal	0.962814769	0.235986341	normal	0.79658904	0.160013226	normal	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: starch binding (GO:2001070);; 	--	--	[OT]	"Posttranslational modification, protein turnover, chaperones;; Signal transduction mechanisms"	Putative phosphatase regulatory subunit	Protein phosphatase 1 regulatory subunit 3G GN=PPP1R3G OS=Homo sapiens (Human) PE=3 SV=1	T	Signal transduction mechanisms	PREDICTED: protein phosphatase 1 regulatory subunit 3G [Ceratotherium simum simum]
ENSG00000219626(FAM228B)	--	2.077956248	36	3.04068	30	1.99928648	36	2.008471252	36	2.792695006	42	3.283199967	30	0.983077111	-0.029570255	normal	0.962785376	0.444968295	normal	0.979476479	-0.259374108	normal	0.964587023	0.061087669	normal	--	--	--	--	--	--	--	--	Protein FAM228B GN=FAM228B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM228B [Galeopterus variegatus]
ENSG00000220008(LINGO3)	--	0	0	0.0301959	1	0	0	0	0	0	0	0.0604949	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Leucine Rich repeat;; Leucine rich repeat;; Leucine rich repeat N-terminal domain	Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 (Precursor) GN=LINGO3 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 3 [Odobenus rosmarus divergens]
ENSG00000220201(ZGLP1)	--	10.34032556	205	14.38352726	253	9.515019985	185	13.12859309	247	14.2123839	257	18.58557977	349	0.93711095	0.23643872	normal	0.966159678	0.001197316	normal	0.00107603	0.901954396	normal	0.244560332	0.387152096	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	GATA zinc finger	GATA-type zinc finger protein 1 GN=ZGLP1 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: GATA-type zinc finger protein 1 [Galeopterus variegatus]
ENSG00000221821(C6orf226)	--	16.2533	83	12.9866	69	13.5919	74	9.95273	54	11.4365	59	15.7443	84	0.775780183	-0.636263931	normal	0.964768591	-0.241575616	normal	0.96768288	0.171285218	normal	0.723064099	-0.218000688	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C6orf226 GN=C6orf226 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C6orf226 homolog [Dasypus novemcinctus]
ENSG00000221823(PPP3R1)	--	54.75772857	2328	57.55650621	2450	54.42040709	2274	43.86185145	1881	44.37876723	1883	41.77047781	1772	0.888697312	-0.338174615	normal	0.775746349	-0.400892143	normal	0.838227984	-0.367867203	normal	0.016474479	-0.370636797	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K06268|4.42377e-132|mcf:102137250|PPP3R1; protein phosphatase 3, regulatory subunit B, alpha; K06268 serine/threonine-protein phosphatase 2B regulatory subunit (A)"	MAPK signaling pathway (ko04010);; Calcium signaling pathway (ko04020);; cGMP-PKG signaling pathway (ko04022);; Oocyte meiosis (ko04114);; Apoptosis (ko04210);; Wnt signaling pathway (ko04310);; Axon guidance (ko04360);; VEGF signaling pathway (ko04370);; Osteoclast differentiation (ko04380);; Natural killer cell mediated cytotoxicity (ko04650);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Oxytocin signaling pathway (ko04921);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Amphetamine addiction (ko05031);; Tuberculosis (ko05152);; HTLV-I infection (ko05166)	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF hand;; EF-hand domain;; EF hand;; EF-hand domain pair;; Secreted protein acidic and rich in cysteine Ca binding region;; Cytoskeletal-regulatory complex EF hand	Calcineurin subunit B type 1 GN=PPP3R1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: calcineurin subunit B type 1 isoform X2 [Canis lupus familiaris]
ENSG00000221826(PSG3)	--	0	0	0.0264535	1	0	0	0.0262706	1	0	0	0.042543726	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06500|0|hsa:5671|PSG3; pregnancy specific beta-1-glycoprotein 3; K06500 pregnancy specific beta-1-glycoprotein (A)	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain	Pregnancy-specific beta-1-glycoprotein 3 (Precursor) GN=PSG3 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1-like [Panthera tigris altaica]
ENSG00000221829(FANCG)	--	17.80137997	923	15.34730107	821	18.54007179	981	15.57202004	810	14.380707	728	15.470241	776	0.949292291	-0.218851757	normal	0.955197013	-0.194489605	normal	0.839484458	-0.345886972	normal	0.173903194	-0.25699023	normal	--	--	--	"K10894|0|hsa:2189|FANCG, FAG, XRCC9; Fanconi anemia, complementation group G; K10894 fanconi anemia group G protein (A)"	Fanconi anemia pathway (ko03460)	--	--	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Fanconi anemia group G protein GN=FANCG OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: Fanconi anemia group G protein [Galeopterus variegatus]
ENSG00000221838(AP4M1)	--	8.83875718	254	8.606751	239	8.315065	251	8.575247	252	9.478488	277	8.67687	249	0.966460859	-0.041982071	normal	0.947750706	0.19032935	normal	0.967044544	-0.019713811	normal	0.925695051	0.043343644	normal	--	--	--	"K12402|0|pon:100174275|AP4M1; adaptor-related protein complex 4, mu 1 subunit; K12402 AP-4 complex subunit mu-1 (A)"	Lysosome (ko04142)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Adaptor complexes medium subunit family;; Clathrin adaptor complex small chain	AP-4 complex subunit mu-1 GN=AP4M1 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: AP-4 complex subunit mu-1 [Balaenoptera acutorostrata scammoni]
ENSG00000221843(C2orf16)	--	0.537272	113	0.421365	85	0.415515	85	0.2867519	45	0.2007985	49	0.3748533	75	0.000631278	-1.329489751	down	0.486364847	-0.797189217	normal	0.96636014	-0.185350629	normal	0.065648889	-0.76363745	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf16 GN=C2orf16 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein LOC101360583 [Trichechus manatus latirostris]
ENSG00000221852(KRTAP1-5)	--	0.388558	6	0.0651209	1	0.759908	11	0.194035	3	0.126696	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: keratin filament (GO:0045095);; 	--	--	[W]	Extracellular structures	"Keratin, high sulfur B2 protein;; Keratin, high sulfur B2 protein"	Keratin-associated protein 1-5 GN=KRTAP1-5 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	"PREDICTED: keratin, high-sulfur matrix protein, B2A-like [Equus caballus]"
ENSG00000221866(PLXNA4)	--	0.112949497	10	0.058193062	11	0.076875221	13	0.388936418	68	0.491829119	71	0.173422252	27	2.90E-07	2.563129846	up	2.19E-07	2.51497193	up	0.915413505	0.966669301	normal	0.004920587	2.264714194	up	--	--	Molecular Function: protein binding (GO:0005515);; 	"K06820|0|ptr:463737|PLXNA4, PLXNA4A; plexin A4; K06820 plexin A (A)"	Axon guidance (ko04360)	[T]	Signal transduction mechanisms	Plexin cytoplasmic RasGAP domain;; Sema domain;; IPT/TIG domain;; Plexin repeat	Plexin-A4 (Precursor) GN=UNQ2820/PRO34003 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: plexin-A4 isoform 2 [Ceratotherium simum simum]
ENSG00000221867(MAGEA3)	--	5.252930291	130	5.656001251	165	4.994490371	143	1.000522345	23	0.881289052	27	1.015556416	25	2.73E-12	-2.452149955	down	2.00E-15	-2.566733984	down	4.04E-13	-2.454470662	down	1.78E-13	-2.566954275	down	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 3 GN=MAGEA3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: melanoma-associated antigen 10-like [Camelus bactrianus]
ENSG00000221869(CEBPD)	--	28.0239	902	35.8321	1193	26.7779	920	42.104	1376	47.8359	1565	75.4116	2481	0.096130939	0.577646914	normal	0.818396921	0.369731739	normal	3.00E-15	1.421443436	up	0.10190399	0.826961718	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K10050|4.85078e-133|hsa:1052|CEBPD, C/EBP-delta, CELF, CRP3, NF-IL6-beta; CCAAT/enhancer binding protein (C/EBP), delta; K10050 CCAAT/enhancer binding protein (C/EBP), delta (A)"	--	[K]	Transcription	Basic region leucine zipper;; bZIP transcription factor	CCAAT/enhancer-binding protein delta GN=CEBPD OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: CCAAT/enhancer-binding protein delta [Odobenus rosmarus divergens]
ENSG00000221878(PSG7)	--	0.025039801	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K06500|0|ptr:741127|PSG3; pregnancy-specific beta-1-glycoprotein 3; K06500 pregnancy specific beta-1-glycoprotein (A)	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Putative pregnancy-specific beta-1-glycoprotein 7 (Precursor) GN=PSG7 OS=Homo sapiens (Human) PE=5 SV=2	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1-like [Panthera tigris altaica]
ENSG00000221883(ARIH2OS)	--	0.345049	8	0.291866	7	0.36596	8	0.338251	8	0.247466	5	0.506837	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein ARIH2OS GN=ARIH2OS OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein ARIH2OS [Galeopterus variegatus]
ENSG00000221886(ZBED8)	--	3.206421	156	4.29062936	196	3.816727352	166	2.407552133	114	3.277854643	158	3.511645883	165	0.786234484	-0.477814413	normal	0.899801273	-0.329517807	normal	0.967328307	-0.016854646	normal	0.490810223	-0.265523098	normal	--	--	--	--	--	--	--	--	Protein ZBED8 GN=ZBED8 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein ZBED8 isoform X3 [Equus przewalskii]
ENSG00000221887(HMSD)	--	0.801583	23	0.37901	11	0.828036	23	0.0681473	2	0.404994	11	0.20572	6	0.018175146	-2.817726917	normal	--	--	--	0.535472749	-1.713382119	normal	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin-like protein HMSD (Precursor) GN=HMSD OS=Homo sapiens (Human) PE=2 SV=1	V	Defense mechanisms	PREDICTED: serpin B6-like isoform X2 [Chrysochloris asiatica]
ENSG00000221890(NPTXR)	--	12.12677312	1253	12.8984631	1355	12.45690952	1435	9.018272607	1087	12.13820286	1358	17.03810924	1658	0.94888908	-0.23555629	normal	0.9824686	-0.018215623	normal	0.966727249	0.199905678	normal	1	0.001496309	normal	--	--	--	--	--	--	--	Pentaxin family;; Concanavalin A-like lectin/glucanases superfamily	Neuronal pentraxin receptor GN=NPTXR OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: neuronal pentraxin receptor [Sus scrofa]
ENSG00000221909(FAM200A)	--	3.459495	140	4.262915	177	4.176055	168	4.692792	199	5.157661	215	4.88751	207	0.74194881	0.472143959	normal	0.931212299	0.257164546	normal	0.920199034	0.290518159	normal	0.312820702	0.335628013	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4371)	Protein FAM200A GN=FAM200A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FAM200A [Equus przewalskii] 
ENSG00000221914(PPP2R2A)	--	32.29981557	1450	36.43375291	1377	32.45926355	1389	37.18985829	1580	29.74852312	1231	31.68011133	1365	0.981304817	0.092945034	normal	0.967345801	-0.182911757	normal	0.982822722	-0.033400406	normal	0.900709545	-0.035516414	normal	[T]	Signal transduction mechanisms	--	"K04354|0|hsa:5520|PPP2R2A, B55A, B55ALPHA, PR52A, PR55A; protein phosphatase 2, regulatory subunit B, alpha (EC:3.1.3.16); K04354 serine/threonine-protein phosphatase 2A regulatory subunit B (A)"	mRNA surveillance pathway (ko03015);; Sphingolipid signaling pathway (ko04071);; PI3K-Akt signaling pathway (ko04151);; AMPK signaling pathway (ko04152);; Adrenergic signaling in cardiomyocytes (ko04261);; Hippo signaling pathway (ko04390);; Tight junction (ko04530);; Dopaminergic synapse (ko04728);; Chagas disease (American trypanosomiasis) (ko05142);; Hepatitis C (ko05160)	[T]	Signal transduction mechanisms	"WD domain, G-beta repeat"	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform GN=PPP2R2A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform [Tupaia chinensis]
ENSG00000221916(C19orf73)	--	3.16419	27	3.69078	33	3.26517	29	1.97347	18	1.90561	16	1.47758	13	0.972471786	-0.575426977	normal	0.835904878	-0.998774652	normal	0.850880666	-1.079769346	normal	0.151538471	-0.943391521	normal	--	--	--	--	--	--	--	--	Putative uncharacterized protein C19orf73 GN=C19orf73 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: putative uncharacterized protein C19orf73 homolog [Galeopterus variegatus]
ENSG00000221923(ZNF880)	--	3.300161808	24	2.580212895	21	1.563444617	29	1.63888656	25	1.665881293	17	1.490128819	18	0.987248046	0.026405191	normal	0.985995042	-0.302061262	normal	0.961896902	-0.65277207	normal	0.725447385	-0.324432041	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Transposase zinc-ribbon domain;; C1-like domain;; XPA protein N-terminal"	Zinc finger protein 880 GN=ZNF880 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 160-like isoform X3 [Galeopterus variegatus]
ENSG00000221926(TRIM16)	--	105.5117459	4614	106.0212042	4715	109.8371136	5062	92.89725905	4015	106.308799	4401	112.0428382	4581	0.977895136	-0.231367602	normal	0.990212933	-0.120812838	normal	0.98904295	-0.152288539	normal	0.395370111	-0.167617911	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; 	"K12006|0|hsa:10626|TRIM16, EBBP; tripartite motif containing 16; K12006 tripartite motif-containing protein 16 (A)"	--	--	--	SPRY domain;; SPRY-associated domain;; B-box zinc finger	Tripartite motif-containing protein 16 GN=TRIM16 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: tripartite motif-containing protein 16 [Ursus maritimus]
ENSG00000221944(TIGD1)	--	2.61693	119	3.14844	143	4.19111	188	2.41038	110	2.70516	122	1.75652	80	0.964279258	-0.142377599	normal	0.944031774	-0.247720866	normal	6.28E-05	-1.225383369	down	0.143081529	-0.549669314	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; CENP-B N-terminal DNA-binding domain;; Tc5 transposase DNA-binding domain	Tigger transposable element-derived protein 1 GN=TIGD1 OS=Homo sapiens (Human) PE=1 SV=1	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: tigger transposable element-derived protein 1-like [Echinops telfairi]
ENSG00000221946(FXYD7)	--	0.904292358	7	0	0	0.367841	2	0.253487	2	0	0	0.687361584	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	K13364|1.42833e-43|pps:100971458|FXYD7; FXYD domain containing ion transport regulator 7; K13364 FXYD domain-containing ion transport regulator 7 (A)	--	--	--	ATP1G1/PLM/MAT8 family	FXYD domain-containing ion transport regulator 7 GN=FXYD7 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: FXYD domain-containing ion transport regulator 7 [Ceratotherium simum simum]
ENSG00000221947(XKR9)	--	0.200936969	8	0.231538111	5	0.511707564	10	0.221595096	9	0.222585164	5	0.274179057	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	XK-related protein	XK-related protein 9 GN=XKR9 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: XK-related protein 9 [Pteropus alecto]
ENSG00000221955(SLC12A8)	--	0.432492762	15	0.195570463	10	0.514940167	27	0.655056655	34	1.08394134	43	0.545919687	28	0.79308431	1.07491576	normal	0.007922394	1.93137423	up	0.985647337	0.041872842	normal	0.107454456	0.993826487	normal	[E]	Amino acid transport and metabolism	Biological Process: transport (GO:0006810);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	"K14428|0|hsa:84561|SLC12A8, CCC9; solute carrier family 12, member 8; K14428 solute carrier family 12 (potassium/chloride transporters), member 8 (A)"	--	[P]	Inorganic ion transport and metabolism	Amino acid permease;; Amino acid permease	Solute carrier family 12 member 8 GN=SLC12A8 OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 12 member 8 [Ceratotherium simum simum]
ENSG00000221963(APOL6)	--	2.923884	497	3.685708	625	2.837202452	473	4.90648	839	4.552964	772	7.719609	1316	0.005964851	0.722854785	normal	0.910187181	0.28270165	normal	7.11E-15	1.465025592	up	0.062785143	0.855672429	normal	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	K14480|0|ggo:101124242|APOL6; apolipoprotein L6 isoform 1; K14480 apolipoprotein L (A)	--	--	--	Apolipoprotein L	Apolipoprotein L6 GN=APOL6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: apolipoprotein L6 [Galeopterus variegatus]
ENSG00000221968(FADS3)	--	30.0748021	939	24.05654319	806	22.29241073	784	24.35089329	778	25.73745029	863	23.2485409	788	0.896178442	-0.30164406	normal	0.974486737	0.077014502	normal	0.976825771	-0.000947643	normal	0.762719635	-0.07945696	normal	[I]	Lipid transport and metabolism	Biological Process: lipid metabolic process (GO:0006629);; 	K10225|0|pps:100980260|FADS3; fatty acid desaturase 3; K10225 fatty acid desaturase 3 (delta-6 desaturase) [EC:1.14.19.-] (A)	--	[I]	Lipid transport and metabolism	Fatty acid desaturase;; Cytochrome b5-like Heme/Steroid binding domain	Fatty acid desaturase 3 GN=FADS3 OS=Homo sapiens (Human) PE=2 SV=1	I	Lipid transport and metabolism	PREDICTED: fatty acid desaturase 3 isoform X1 [Tupaia chinensis]
ENSG00000221970(OR2A1)	--	0.090553	1	0	0	0	0	0	0	0.0880599	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:346528|OR2A1; olfactory receptor, family 2, subfamily A, member 1; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 2A1/2A42 GN=OR2A42 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 2A1/2A42 [Galeopterus variegatus]
ENSG00000221983(UBA52)	--	592.3606042	3972	537.6723792	3732	534.4061701	3783	605.6755766	4430	597.1615967	4147	545.0401806	3799	0.989515463	0.126562442	normal	0.988505456	0.130642267	normal	0.991817664	-0.002201628	normal	0.713737845	0.085875855	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: structural constituent of ribosome (GO:0003735);; Molecular Function: protein binding (GO:0005515);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02927|2.48652e-69|shr:100933021|UBA52; ubiquitin A-52 residue ribosomal protein fusion product 1; K02927 large subunit ribosomal protein L40e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ubiquitin family;; Ribosomal L40e family;; Ubiquitin-2 like Rad60 SUMO-like;; Ubiquitin-like domain	60S ribosomal protein L40 (Precursor) GN=UBA52 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ubiquitin-60S ribosomal protein L40 isoform X2 [Leptonychotes weddellii]
ENSG00000221988(PPT2)	--	6.34671615	203	4.816839711	125	5.822980202	194	5.286909395	162	6.058639511	186	6.963963518	224	0.88251762	-0.353317315	normal	0.604652324	0.546495521	normal	0.948850681	0.197715189	normal	0.831092618	0.112158447	normal	[R]	General function prediction only	Molecular Function: palmitoyl hydrolase activity (GO:0098599);; 	K01074|0|nle:100599270|PPT2; palmitoyl-protein thioesterase 2; K01074 palmitoyl-protein thioesterase [EC:3.1.2.22] (A)	Fatty acid elongation (ko00062);; Fatty acid metabolism (ko01212);; Lysosome (ko04142)	[IO]	"Lipid transport and metabolism;; Posttranslational modification, protein turnover, chaperones"	Palmitoyl protein thioesterase;; Alpha/beta hydrolase family;; Putative serine esterase (DUF676)	Lysosomal thioesterase PPT2 (Precursor) GN=PPT2 OS=Homo sapiens (Human) PE=1 SV=4	G	Carbohydrate transport and metabolism	PREDICTED: lysosomal thioesterase PPT2 isoform 1 [Tursiops truncatus]
ENSG00000221994(ZNF630)	--	0.539655691	30	0.535401687	24	0.304672173	15	0.525013267	30	0.411212006	20	0.609727055	31	0.985137509	-0.029330151	normal	0.984715744	-0.26606975	normal	0.881512875	0.96972614	normal	0.835100739	0.209181903	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:57232|ZNF630, dJ54B20.2; zinc finger protein 630; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; TFIIH C1-like domain"	Zinc finger protein 630 GN=ZNF630 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 630 [Odobenus rosmarus divergens]
ENSG00000222009(BTBD19)	--	1.844916	150	2.646512799	232	2.049147779	145	2.669869526	206	4.17395993	320	6.017216799	460	0.811505198	0.423137981	normal	0.707241474	0.440068618	normal	1.04E-13	1.647112323	up	0.175766349	0.884373413	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	BTB/POZ domain;; BTB And C-terminal Kelch	BTB/POZ domain-containing protein 19 GN=BTBD19 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 19 [Orcinus orca] 
ENSG00000222011(FAM185A)	--	7.14578885	140	6.6497627	163	7.0456224	160	5.8487581	159	5.515057	141	7.81091092	172	0.960111408	0.151209851	normal	0.945289424	-0.22832342	normal	0.96428528	0.095177414	normal	0.998167054	0.006832341	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4098);; Domain of unknown function (DUF4097)	Protein FAM185A GN=FAM185A OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: protein FAM185A isoform X1 [Tupaia chinensis]
ENSG00000222028(PSMB11)	--	0.0639922	2	0.0310374	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K11598|0|hsa:122706|PSMB11, BETA5T; proteasome (prosome, macropain) subunit, beta type, 11 (EC:3.4.25.1); K11598 20S proteasome subunit beta 11 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-11 (Precursor) GN=PSMB11 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-11 [Oryctolagus cuniculus] 
ENSG00000222046(DCDC2B)	--	0.12081	3	0.0396225	1	0	0	0.0398886	1	0.117895	2	0.0398856	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	--	--	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	Doublecortin	Doublecortin domain-containing protein 2B GN=DCDC2B OS=Homo sapiens (Human) PE=2 SV=1	DZ	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	PREDICTED: LOW QUALITY PROTEIN: doublecortin domain-containing protein 2B [Galeopterus variegatus]
ENSG00000222047(C10orf55)	--	0.789403195	32	0.601758632	25	0.916352081	38	0.70401781	29	0.596925768	24	0.314218266	13	0.983597158	-0.164547883	normal	0.985910063	-0.07564933	normal	0.240740301	-1.452727172	normal	0.453082505	-0.548218604	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C10orf55 GN=C10orf55 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: urokinase-type plasminogen activator [Loxodonta africana]
ENSG00000223401(RP11-211G3.2)	--	0	0	0	0	0	0	0.141012	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000223443(USP17L2)	--	0	0	0	0	0	0	0.028429	1	0.0278967	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11845|0|hsa:377630|USP17L2, DUB-3, DUB3, USP17; ubiquitin specific peptidase 17-like family member 2 (EC:3.4.19.12); K11845 ubiquitin carboxyl-terminal hydrolase 17 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Hyaluronan / mRNA binding family	Ubiquitin carboxyl-terminal hydrolase 17 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 17-like protein 22-like [Ceratotherium simum simum]
ENSG00000223496(EXOSC6)	--	12.2464	841	13.9425	969	11.5056	791	12.8267	887	12.7831	876	13.4964	928	0.977004575	0.045914362	normal	0.964782943	-0.166718553	normal	0.948223906	0.221763846	normal	0.929798672	0.027747327	normal	--	--	--	"K12587|1.37797e-96|hsa:118460|EXOSC6, EAP4, MTR3, Mtr3p, hMtr3p, p11; exosome component 6; K12587 exosome complex component MTR3 (A)"	RNA degradation (ko03018)	[J]	"Translation, ribosomal structure and biogenesis"	"3' exoribonuclease family, domain 1"	Exosome complex component MTR3 GN=EXOSC6 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: exosome complex component MTR3 [Erinaceus europaeus]
ENSG00000223501(VPS52)	--	7.005957	403	7.091098	414	7.945751	462	6.630365	382	7.234628	416	7.083551	409	0.964016607	-0.107617958	normal	0.969140033	-0.014421246	normal	0.951572576	-0.183444822	normal	0.735917474	-0.104325587	normal	--	--	Cellular Component: exocyst (GO:0000145);; Biological Process: exocytosis (GO:0006887);; 	--	--	[UZ]	"Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	Vps52 / Sac2 family;; Exocyst complex component Sec3	Vacuolar protein sorting-associated protein 52 homolog GN=VPS52 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: vacuolar protein sorting-associated protein 52 homolog [Oryctolagus cuniculus]
ENSG00000223510(CDRT15)	--	0.262531	3	0.0852368	1	0.249616	2	0.251468	3	0.595690486	6	0.430212672	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	CMT1A duplicated region transcript 15 protein GN=CDRT15 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000223547(ZNF844)	--	0	0	0	0	0	0	0.007640983	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; KRAB box;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Probable zinc-binding domain;; DDE_Tnp_1-like zinc-ribbon"	Zinc finger protein 844 GN=ZNF844 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 709-like isoform X1 [Equus caballus]
ENSG00000223569(USP17L15)	--	0.0314388	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Hyaluronan / mRNA binding family	Ubiquitin carboxyl-terminal hydrolase 17-like protein 15 GN=USP17L15 OS=Homo sapiens (Human) PE=3 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 17-like protein 22-like [Ceratotherium simum simum]
ENSG00000223572(CKMT1A)	--	0	0	0	0	0	0	0.115029985	4	0.084772133	2	0.02848929	1	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	"Molecular Function: kinase activity (GO:0016301);; Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	"K00933|0|pon:100435206|creatine kinase U-type, mitochondrial; K00933 creatine kinase [EC:2.7.3.2] (A)"	Arginine and proline metabolism (ko00330)	[C]	Energy production and conversion	"ATP:guanido phosphotransferase, C-terminal catalytic domain;; ATP:guanido phosphotransferase, N-terminal domain"	"Creatine kinase U-type, mitochondrial (Precursor) GN=CKMT1B OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: creatine kinase U-type, mitochondrial isoform 1 [Canis lupus familiaris]"
ENSG00000223573(TINCR)	--	2.957310215	206	2.908131549	208	3.29883	235	0.562796	39	0.9837601	62	1.14586	80	1.11E-16	-2.386206176	down	5.95E-10	-1.743021339	down	8.99E-09	-1.545013687	down	2.26E-11	-1.861088135	down	--	--	--	--	--	--	--	Ubiquitin family	--	--	--	PREDICTED: LOW QUALITY PROTEIN: zinc/RING finger protein 4-like [Chrysochloris asiatica]
ENSG00000223601(EBLN1)	--	0	0	0	0	0	0	0	0	0	0	0.0549717	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Borna disease virus P40 protein	Endogenous Bornavirus-like nucleoprotein 1 GN=EBLN1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: endogenous Bornavirus-like nucleoprotein 1-like [Chrysochloris asiatica]
ENSG00000223658(C1GALT1C1L)	--	2.23049	40	2.23579	40	2.22437	39	1.20927	22	0.488205	8	0.995611	18	0.861238074	-0.848736315	normal	0.003256145	-2.145007935	down	0.703435643	-1.061791989	normal	0.018017095	-1.332222552	normal	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	--	C1GALT1-specific chaperone 1 OS=Homo sapiens (Human) PE=1 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: C1GALT1-specific chaperone 1-like [Trichechus manatus latirostris]
ENSG00000224051(CPTP)	--	10.30161402	406	9.877506511	401	12.56996	517	11.28196571	449	10.430235	412	8.971267875	358	0.963950186	0.113993148	normal	0.968909925	0.017550247	normal	0.291048452	-0.536599008	normal	0.624077398	-0.140600913	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Molecular Function: glycolipid transporter activity (GO:0017089);; Biological Process: glycolipid transport (GO:0046836);; Molecular Function: glycolipid binding (GO:0051861);; 	--	--	--	--	Glycolipid transfer protein (GLTP)	Ceramide-1-phosphate transfer protein GN=CPTP OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: glycolipid transfer protein domain-containing protein 1 [Tursiops truncatus]
ENSG00000224109(CENPVL3)	--	0.0861437	1	0	0	0.0787258	0	0.168898	2	0.165634	1	0.335474	4	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Biological Process: metabolic process (GO:0008152);; Molecular Function: carbon-sulfur lyase activity (GO:0016846);; 	--	--	[S]	Function unknown	Glutathione-dependent formaldehyde-activating enzyme	Centromere protein V GN=CENPV OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centromere protein V-like [Leptonychotes weddellii]
ENSG00000224383(PRR29)	--	1.936719326	65	2.210305173	57	3.846976156	43	0.870343656	43	1.429363187	46	0.537730908	24	0.872162026	-0.60910252	normal	0.962867913	-0.321247631	normal	0.860325017	-0.810916219	normal	0.3188535	-0.56925965	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4587)	Proline-rich protein 29 GN=PRR29 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C17orf72 homolog isoform X4 [Mustela putorius furo] 
ENSG00000224389(C4B)	--	0	0	0	0	0	0	0.009118109	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	"K03989|0|hsa:721|C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CH, CO4, CPAMD3; complement component 4B (Chido blood group); K03989 complement component 4 (A)"	Complement and coagulation cascades (ko04610);; Pertussis (ko05133);; Staphylococcus aureus infection (ko05150);; Systemic lupus erythematosus (ko05322)	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; A-macroglobulin receptor;; Alpha-2-macroglobulin family;; Alpha-2-macroglobulin family N-terminal region;; UNC-6/NTR/C345C module;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region;; Anaphylotoxin-like domain;; Prenyltransferase-like	Complement C4 gamma chain (Precursor) GN=C4B_2 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: complement C4-A isoform X1 [Galeopterus variegatus]
ENSG00000224420(ADM5)	--	3.83868	104	2.95915	81	2.75203	76	2.98713	80	3.21938	86	2.53283	69	0.912300968	-0.402541543	normal	0.970647959	0.063831543	normal	0.970748727	-0.144671988	normal	0.777925229	-0.173213564	normal	--	--	--	--	--	--	--	--	Putative adrenomedullin-5-like protein (Precursor) GN=ADM5 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: putative adrenomedullin-5-like protein [Galeopterus variegatus]
ENSG00000224531(SMIM13)	--	7.797218766	522	11.082335	734	9.79245	643	6.48979	439	6.945012843	463	7.64281	512	0.907979644	-0.279761833	normal	0.0192544	-0.684402333	normal	0.850182557	-0.33607857	normal	0.047625845	-0.446210273	normal	--	--	--	--	--	--	--	--	Small integral membrane protein 13 GN=SMIM13 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 13 [Ochotona princeps]
ENSG00000224586(GPX5)	--	0	0	0	0	0	0	0.043552652	1	0	0	0.042948966	1	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: glutathione peroxidase activity (GO:0004602);; Biological Process: response to oxidative stress (GO:0006979);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00432|2.48848e-158|hsa:2880|GPX5, HEL-S-75p; glutathione peroxidase 5 (EC:1.11.1.9); K00432 glutathione peroxidase [EC:1.11.1.9] (A)"	Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590);; Thyroid hormone synthesis (ko04918)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glutathione peroxidase	Epididymal secretory glutathione peroxidase (Precursor) GN=GPX5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: epididymal secretory glutathione peroxidase [Myotis brandtii] 
ENSG00000224712(NPIPA3)	--	0	0	0	0	0	0	0.0466872	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A2 GN=NPIPA2 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000224877(NDUFAF8)	--	114.0412656	760	136.3946914	955	144.4563208	1019	156.4865134	1078	130.0746423	872	150.4445919	1019	0.449377443	0.472647723	normal	0.967277046	-0.152346577	normal	0.979808863	-0.008279155	normal	0.728258727	0.097780595	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C17orf89 GN=C17orf89 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C17orf89 isoform X1 [Leptonychotes weddellii]
ENSG00000224940(PRRT4)	--	0.655625822	23	0.451953999	11	0.28656277	7	0.182549128	5	0.651116221	19	0.259718386	7	0.327762096	-1.934590025	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Proline-rich transmembrane protein 4 (Precursor) GN=PRRT4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: proline-rich transmembrane protein 4 [Ceratotherium simum simum]
ENSG00000224982(TMEM233)	--	0.0392997	2	0.0393487	2	0	0	0.391019	20	0.418341	21	0.408999	21	--	--	--	0.065951266	2.664141949	normal	0.00217057	3.892046042	up	--	--	--	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Interferon-induced transmembrane protein	Transmembrane protein 233 GN=TMEM233 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: transmembrane protein 233 [Tupaia chinensis]
ENSG00000225190(PLEKHM1)	--	10.534544	1336	14.807973	1751	13.16785748	1653	15.31667288	1722	12.5554031	1466	23.86717616	2485	0.876879122	0.334992782	normal	0.936409753	-0.277458249	normal	0.091865317	0.579432423	normal	0.630477742	0.239173832	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Domain of unknown function (DUF4206);; RUN domain	Pleckstrin homology domain-containing family M member 1 GN=PLEKHM1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: pleckstrin homology domain-containing family M member 1 [Ceratotherium simum simum]
ENSG00000225362(CT62)	--	0.58516577	23	0.612819	26	1.120909	35	0.244070022	11	0.4686446	7	0.17464685	8	0.935554661	-0.996774489	normal	0.37188979	-1.711392538	normal	0.031879106	-1.947978486	normal	0.006357677	-1.713615261	down	--	--	--	--	--	--	--	--	Cancer/testis antigen 62 GN=CT62 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: LOW QUALITY PROTEIN: cancer/testis antigen 62, partial [Galeopterus variegatus]"
ENSG00000225526(MKRN2OS)	--	0.0632675	1	0	0	0.244839	3	0.123786	2	0.0615727	0	0.124583	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	MKRN2 opposite strand protein GN=MKRN2OS OS=Homo sapiens (Human) PE=4 SV=1	A	RNA processing and modification	PREDICTED: putative uncharacterized protein C3orf83 homolog [Galeopterus variegatus]
ENSG00000225614(ZNF469)	--	3.01188	961	3.67783	1191	3.39868	1112	0.6497188	210	2.400737	765	2.445337	787	0	-2.21663043	down	0.021506792	-0.659015141	normal	0.311351275	-0.506190196	normal	0.043977609	-0.907372863	normal	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; C2H2-type zinc finger"	Zinc finger protein 469 GN=ZNF469 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: zinc finger protein 469 [Galeopterus variegatus]
ENSG00000225663(MCRIP1)	--	39.666728	795	28.23684098	616	38.3635404	782	44.80500167	846	43.73544957	846	44.88147371	925	0.975826453	0.058760449	normal	0.618672801	0.435385234	normal	0.943157741	0.233577536	normal	0.234470539	0.234316398	normal	--	--	--	--	--	--	--	FAM195 family	Protein FAM195B GN=FAM195B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	hypothetical protein PAL_GLEAN10014529 [Pteropus alecto]
ENSG00000225697(SLC26A6)	--	7.418965838	326	6.663976303	304	7.826698315	303	6.748107178	309	7.853483177	342	10.42807346	423	0.962749562	-0.107576517	normal	0.956414256	0.147804935	normal	0.561877493	0.471049783	normal	0.5400727	0.182745552	normal	[P]	Inorganic ion transport and metabolism	Biological Process: sulfate transport (GO:0008272);; Molecular Function: sulfate transmembrane transporter activity (GO:0015116);; Cellular Component: integral component of membrane (GO:0016021);; 	"K14704|0|pps:103786083|SLC26A6; solute carrier family 26 (anion exchanger), member 6; K14704 solute carrier family 26 (sulfate anion transporter), member 6 (A)"	Mineral absorption (ko04978)	[P]	Inorganic ion transport and metabolism	Sulfate transporter family;; Sulfate transporter N-terminal domain with GLY motif;; STAS domain	Solute carrier family 26 member 6 GN=SLC26A6 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: solute carrier family 26 member 6 isoform X3 [Equus przewalskii]
ENSG00000225828(FAM229A)	--	2.09193	16	0.998235	8	1.07643	8	1.25699	10	1.88459	14	0.756655	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	UPF0731 family	Protein FAM229A GN=FAM229A OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: protein FAM229A [Bubalus bubalis]
ENSG00000225830(ERCC6)	--	4.337903015	396	3.685867678	403	3.626752788	413	3.079084004	287	3.5410444	313	3.519138443	390	0.498054827	-0.493024118	normal	0.79068018	-0.384402136	normal	0.966011252	-0.090617585	normal	0.193675586	-0.312102726	normal	[KL]	"Transcription;; Replication, recombination and repair"	Molecular Function: ATP binding (GO:0005524);; 	"K10841|0|hsa:2074|ERCC6, ARMD5, CKN2, COFS, COFS1, CSB, RAD26, UVSS1; excision repair cross-complementation group 6; K10841 DNA excision repair protein ERCC-6 (A)"	Nucleotide excision repair (ko03420)	[KL]	"Transcription;; Replication, recombination and repair"	SNF2 family N-terminal domain;; Helicase conserved C-terminal domain	DNA excision repair protein ERCC-6 GN=ERCC6 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: DNA excision repair protein ERCC-6 [Galeopterus variegatus]
ENSG00000225899(FRG2B)	--	0	0	0	0	0	0	0.02820816	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Facioscapulohumeral muscular dystrophy candidate 2	Protein FRG2-like-1 GN=FRG2B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein FRG2-like-1 [Galeopterus variegatus]
ENSG00000225921(NOL7)	--	38.36797479	863	38.2157576	881	40.018633	921	44.053909	1014	41.78410059	945	37.96190064	866	0.956654313	0.201461776	normal	0.975464299	0.079613786	normal	0.974411824	-0.096961354	normal	0.817059731	0.062547562	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	--	--	--	--	NUC129 domain	Nucleolar protein 7 GN=NOL7 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nucleolar protein 7 [Loxodonta africana]
ENSG00000225968(ELFN1)	--	0.030168592	2	0	0	0.014365565	0	0.015008524	1	0.07204943	4	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	"K17567|0|hsa:392617|ELFN1, PPP1R28; extracellular leucine-rich repeat and fibronectin type III domain containing 1; K17567 protein phosphatase 1 regulatory subunit 28 (A)"	--	--	--	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Protein ELFN1 (Precursor) GN=ELFN1 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein ELFN1 [Tupaia chinensis]
ENSG00000226124(FTCDNL1)	--	3.614439938	70	2.558190557	62	2.70675035	66	1.683533742	31	2.259753046	57	1.438501432	39	0.082506561	-1.166394292	normal	0.972823673	-0.139190692	normal	0.746755357	-0.744834365	normal	0.189400631	-0.660995234	normal	--	--	Molecular Function: folic acid binding (GO:0005542);; Biological Process: metabolic process (GO:0008152);; Molecular Function: transferase activity (GO:0016740);; 	--	--	--	--	"Formiminotransferase domain, N-terminal subdomain"	Formiminotransferase N-terminal subdomain-containing protein (Precursor) GN=FTCDNL1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: formiminotransferase N-terminal subdomain-containing protein-like [Echinops telfairi]
ENSG00000226174(TEX22)	--	0.5815314	37	0.345315321	24	0.595067	38	0.24095012	16	0.31098021	20	0.404686276	27	0.626526478	-1.164733095	normal	0.984715744	-0.26606975	normal	0.96517063	-0.478630456	normal	0.3207312	-0.671207654	normal	--	--	--	--	--	--	--	--	Testis-expressed sequence 22 protein GN=TEX22 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-expressed sequence 22 protein [Ceratotherium simum simum]
ENSG00000226321(CROCC2)	--	0	0	0.0069753	1	0	0	0	0	0.00717175	0	0.00728099	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Ciliary rootlet component, centrosome cohesion"	Putative ciliary rootlet coiled-coil protein-like 3 protein OS=Homo sapiens (Human) PE=5 SV=2	S	Function unknown	PREDICTED: putative ciliary rootlet coiled-coil protein-like 3 protein [Orycteropus afer afer]
ENSG00000226430(USP17L7)	--	0.0276888	1	0	0	0.0272817	0	0.0274989	1	0	0	0.0274323	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Hyaluronan / mRNA binding family	Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7 GN=USP17L7 OS=Homo sapiens (Human) PE=3 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 17-like protein 22-like [Ceratotherium simum simum]
ENSG00000226479(TMEM185B)	--	35.08517	1742	29.71454	1545	30.76569	1533	22.09175	1135	21.6335	1098	21.37019	1188	0.01928784	-0.648170397	normal	0.300786215	-0.513555915	normal	0.797142978	-0.375692109	normal	0.000453019	-0.515782661	normal	--	--	--	--	--	[S]	Function unknown	Transmembrane Fragile-X-F protein	Transmembrane protein 185B GN=TMEM185B OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 185B isoform X1 [Eptesicus fuscus]
ENSG00000226650(KIF4B)	--	0.00932836	1	0	0	0	0	0.0186511	2	0.0181454	1	0.00927898	1	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	K10395|0|hsa:285643|KIF4B; kinesin family member 4B; K10395 kinesin family member 4/21/27 (A)	--	[Z]	Cytoskeleton	Kinesin motor domain	Chromosome-associated kinesin KIF4B GN=KIF4B OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: chromosome-associated kinesin KIF4A [Odobenus rosmarus divergens]
ENSG00000226690(AC005281.1)	--	0	0	0	0	0	0	0	0	0.0946922	0	0.195314125	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: uncharacterized protein LOC102157031 isoform X1 [Canis lupus familiaris]
ENSG00000226742(HSBP1L1)	--	12.24835	222	11.83745	226	12.71057	236	19.3352	310	16.41144	260	20.41605	337	0.690737485	0.448240544	normal	0.950359869	0.179640874	normal	0.513753649	0.502959524	normal	0.141053228	0.386180499	normal	--	--	--	--	--	[KO]	"Transcription;; Posttranslational modification, protein turnover, chaperones"	Heat shock factor binding protein 1	Heat shock factor-binding protein 1-like protein 1 GN=HSBP1L1 OS=Homo sapiens (Human) PE=3 SV=2	K	Transcription	PREDICTED: heat shock factor-binding protein 1-like protein 1 [Odobenus rosmarus divergens]
ENSG00000226761(TAS2R46)	--	0.201405	2	0.203888	2	0	0	0.195274	2	0.195151	1	0.196206	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:259292|TAS2R46, T2R46, T2R54; taste receptor, type 2, member 46; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 46 GN=TAS2R46 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 20-like [Tupaia chinensis]
ENSG00000226887(ERVMER34-1)	--	0.556261526	31	0.493050248	24	0.860333	47	0.394866745	25	0.306211499	19	0.312491671	17	0.980606029	-0.32329298	normal	0.983439914	-0.334705598	normal	0.123048517	-1.397690554	normal	0.239088943	-0.763054241	normal	--	--	--	--	--	--	--	ENV polyprotein (coat polyprotein)	Endogenous retrovirus group MER34 member 1 Env polyprotein (Precursor) GN=ERVMER34-1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: HERV-MER_4q12 provirus ancestral Env polyprotein-like isoform X1 [Equus caballus] 
ENSG00000226979(LTA)	--	0.135264181	3	0	0	0.177551233	3	0	0	0.043843948	0	0.245718523	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	"K05468|2.30807e-121|hsa:4049|LTA, LT, TNFB, TNFSF1; lymphotoxin alpha; K05468 lymphotoxin alpha (TNF superfamily, member 1) (A)"	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; TNF signaling pathway (ko04668);; Type I diabetes mellitus (ko04940);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168)	--	--	TNF(Tumour Necrosis Factor) family	Lymphotoxin-alpha (Precursor) GN=LTA OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: lymphotoxin-alpha [Ceratotherium simum simum]
ENSG00000227051(C14orf132)	--	14.09411465	1483	8.882278004	1307	11.05076085	1300	5.330969001	790	6.511999891	869	5.913757008	820	5.12E-06	-0.938071183	normal	0.059521773	-0.609386469	normal	0.0125811	-0.672113866	normal	2.37E-07	-0.743475276	normal	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: putative uncharacterized protein C14orf132 homolog [Oryctolagus cuniculus]
ENSG00000227057(WDR46)	--	16.71096921	816	16.0086403	792	18.1963	914	16.62589844	830	17.82952214	877	14.5527	723	0.97725987	-0.006278358	normal	0.969896134	0.125422202	normal	0.83801396	-0.345845032	normal	0.780259177	-0.074898271	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	K14768|0|ggo:101146632|WDR46; WD repeat-containing protein 46 isoform 1; K14768 U3 small nucleolar RNA-associated protein 7 (A)	--	[A]	RNA processing and modification	"BING4CT (NUC141) domain;; WD domain, G-beta repeat"	WD repeat-containing protein 46 GN=WDR46 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: WD repeat-containing protein 46 [Equus przewalskii]
ENSG00000227124(ZNF717)	--	6.48296975	256	5.545016229	244	6.277376	221	5.954611673	219	4.999381174	202	4.57234944	210	0.929483784	-0.25439238	normal	0.911859376	-0.291960285	normal	0.964389597	-0.081377154	normal	0.53187707	-0.213909604	normal	[R]	General function prediction only	--	"K09228|0|hsa:100131827|ZNF717, X17, ZNF838; zinc finger protein 717; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; DDE_Tnp_1-like zinc-ribbon"	Zinc finger protein 717 GN=ZNF717 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	"PREDICTED: zinc finger protein 91-like, partial [Ochotona princeps]"
ENSG00000227234(SPANXB1)	--	1.83796	8	2.01144	9	1.50691	6	0.629019	3	1.10825	4	0.218078	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Sperm protein associated with nucleus, mapped to X chromosome"	Sperm protein associated with the nucleus on the X chromosome B/F GN=SPANXF1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000227268(KLLN)	--	0.897257	65	1.0809	79	0.813639	59	0.646768	47	0.653857	47	0.968224	71	0.927401302	-0.485064386	normal	0.624982882	-0.751750131	normal	0.964877418	0.252895987	normal	0.589063002	-0.319361249	normal	--	--	--	--	--	--	--	--	Killin GN=KLLN OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	"PREDICTED: LOW QUALITY PROTEIN: killin, p53-regulated DNA replication inhibitor [Lipotes vexillifer]"
ENSG00000227345(PARG)	--	11.72522	881	12.2587185	905	12.1265276	892	13.19919285	1012	13.21533108	986	12.1475201	915	0.965024288	0.168888141	normal	0.974152211	0.102079844	normal	0.978134562	0.028389069	normal	0.678807371	0.099863789	normal	--	--	Molecular Function: poly(ADP-ribose) glycohydrolase activity (GO:0004649);; Biological Process: carbohydrate metabolic process (GO:0005975);; 	"K07759|0|hsa:8505|PARG, PARG99; poly (ADP-ribose) glycohydrolase (EC:3.2.1.143); K07759 poly(ADP-ribose) glycohydrolase [EC:3.2.1.143] (A)"	--	[T]	Signal transduction mechanisms	Poly (ADP-ribose) glycohydrolase (PARG)	Poly(ADP-ribose) glycohydrolase GN=PARG OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: poly(ADP-ribose) glycohydrolase isoform X1 [Galeopterus variegatus]
ENSG00000227471(AKR1B15)	--	1.111096131	34	0.814179019	25	1.219456	33	1.7798	39	2.070232632	63	1.241277	34	0.981264337	0.160338628	normal	0.072367139	1.262348507	normal	0.983513799	0.033274956	normal	0.388641303	0.542936114	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Aldo/keto reductase family	Aldo-keto reductase family 1 member B15 GN=AKR1B15 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: aldo-keto reductase family 1 member B10-like isoform 1 [Ceratotherium simum simum]
ENSG00000227507(LTB)	--	0.194025641	2	0	0	0	0	0.0844055	1	0.280301374	2	0.0853566	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: tumor necrosis factor receptor binding (GO:0005164);; Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; 	"K03157|3.23036e-154|hsa:4050|LTB, TNFC, TNFSF3, p33; lymphotoxin beta (TNF superfamily, member 3); K03157 lymphotoxin beta (TNF superfamily, member 3) (A)"	Cytokine-cytokine receptor interaction (ko04060);; NF-kappa B signaling pathway (ko04064);; Rheumatoid arthritis (ko05323)	--	--	TNF(Tumour Necrosis Factor) family	Lymphotoxin-beta GN=LTB OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: lymphotoxin-beta isoform X1 [Galeopterus variegatus]
ENSG00000228049(POLR2J2)	--	8.73213	69	8.085	93	19.001019	96	11.17998	76	9.261257	78	6.545551	93	0.972751892	0.106314673	normal	0.952772487	-0.270375456	normal	0.97079277	-0.05324293	normal	0.905275811	-0.083199517	normal	[K]	Transcription	"Molecular Function: DNA-directed RNA polymerase activity (GO:0003899);; Biological Process: transcription, DNA-templated (GO:0006351);; Molecular Function: protein dimerization activity (GO:0046983);; "	K03008|1.55421e-94|ggo:101130894|DNA-directed RNA polymerase II subunit RPB11-a-like; K03008 DNA-directed RNA polymerase II subunit RPB11 (A)	Purine metabolism (ko00230);; Pyrimidine metabolism (ko00240);; RNA polymerase (ko03020);; Huntington's disease (ko05016);; Epstein-Barr virus infection (ko05169)	[K]	Transcription	RNA polymerase Rpb3/Rpb11 dimerisation domain;; RNA polymerase Rpb3/Rpb11 dimerisation domain	DNA-directed RNA polymerase II subunit RPB11-b1 GN=POLR2J2 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: DNA-directed RNA polymerase II subunit RPB11-a isoform X1 [Eptesicus fuscus]
ENSG00000228300(C19orf24)	--	36.8169	468	43.7263	555	38.9386	515	32.20685	426	32.3553	402	36.7549	454	0.955767771	-0.165916144	normal	0.474208895	-0.485158228	normal	0.950825176	-0.189578239	normal	0.203968466	-0.28371127	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF1180)	Uncharacterized membrane protein C19orf24 (Precursor) GN=C19orf24 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	"PREDICTED: uncharacterized membrane protein C19orf24 homolog, partial [Ailuropoda melanoleuca] "
ENSG00000228439(TSTD3)	--	2.49178	30	2.09143	26	3.83861	47	2.428707	27	1.20399	14	1.22533	15	0.984317949	-0.173465489	normal	0.94200457	-0.846458067	normal	0.04346134	-1.562592713	normal	0.150883387	-0.901467506	normal	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Rhodanese-like domain	Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 GN=TSTD3 OS=Homo sapiens (Human) PE=3 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3 isoform X1 [Oryctolagus cuniculus]
ENSG00000228474(OST4)	--	242.079076	1402	242.50894	1461	215.57029	1327	213.316377	1318	188.08984	1098	210.777936	1269	0.977754131	-0.119832764	normal	0.633670258	-0.432985763	normal	0.980733873	-0.072683032	normal	0.264094943	-0.20681407	normal	--	--	--	--	--	--	--	--	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 GN=OST4 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4 isoform X1 [Capra hircus] 
ENSG00000228486(LINC01125)	--	0.375620026	4	0	0	0	0	0.24601723	2	0.134712	0	0.144005487	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: uncharacterized protein LOC102473405 [Tupaia chinensis]
ENSG00000228570(NUTM2E)	--	0.0890702	7	0.041363718	3	0.094293098	6	0.079433	6	0.2584303	20	0.110905087	9	--	--	--	0.279237468	2.236150692	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	NUT protein N terminus;; NUT protein C terminal	NUT family member 2E GN=NUTM2E OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: NUT family member 2G-like [Equus caballus]
ENSG00000228594(FNDC10)	--	9.34002	275	8.11298	241	8.77745	268	7.51957	223	6.58132	195	7.21571	215	0.880852487	-0.331161081	normal	0.891925567	-0.324715628	normal	0.888579371	-0.324141368	normal	0.255166606	-0.329909404	normal	--	--	--	--	--	--	--	--	Fibronectin type-III domain-containing transmembrane protein C1orf233 (Precursor) GN=C1orf233 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: fibronectin type-III domain-containing transmembrane protein C1orf233 homolog [Odobenus rosmarus divergens]
ENSG00000228623(ZNF883)	--	2.68E-18	0	0.000479601	0	6.41E-14	0	2.16E-05	0	2.46E-08	0	0.299987	11	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; TFIIH C1-like domain;; Transposase zinc-ribbon domain;; BED zinc finger;; Zinc-finger of C2H2 type"	Zinc finger protein 883 GN=ZNF883 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 569-like [Galeopterus variegatus]
ENSG00000228696(ARL17B)	--	0.214265	2	0.277452	3	1.5645	13	0.2188226	2	0.500713	5	0.10456	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTP binding (GO:0005525);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	ADP-ribosylation factor family	ADP-ribosylation factor-like protein 17 GN=ARL17B OS=Homo sapiens (Human) PE=2 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ADP-ribosylation factor 2-like isoform X2 [Chrysochloris asiatica] 
ENSG00000228716(DHFR)	--	40.82718272	2660	44.57534345	2859	51.47195828	3223	39.20564997	2644	34.02198414	2224	30.50689252	1948	0.988956428	-0.03951344	normal	0.830260373	-0.383549689	normal	0.001868761	-0.734254001	normal	0.033960813	-0.380904375	normal	[H]	Coenzyme transport and metabolism	Molecular Function: dihydrofolate reductase activity (GO:0004146);; Biological Process: glycine biosynthetic process (GO:0006545);; Biological Process: nucleotide biosynthetic process (GO:0009165);; Biological Process: oxidation-reduction process (GO:0055114);; 	"K00287|3.10121e-136|hsa:1719|DHFR, DHFRP1, DYR; dihydrofolate reductase (EC:1.5.1.3); K00287 dihydrofolate reductase [EC:1.5.1.3] (A)"	One carbon pool by folate (ko00670);; Folate biosynthesis (ko00790)	[H]	Coenzyme transport and metabolism	Dihydrofolate reductase	Dihydrofolate reductase GN=DHFR OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: dihydrofolate reductase [Tupaia chinensis] 
ENSG00000229117(RPL41)	--	3691.7069	16166	3560.9045	16203	3619.9247	16823	4366.0683	21008	4056.276	17704	4100.7931	18781	0.971553107	0.347114796	normal	0.9968164	0.106378344	normal	0.996230136	0.150534626	normal	0.350398688	0.203435231	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	hypothetical protein D623_10010899 [Myotis brandtii]
ENSG00000229474(PATL2)	--	0.029585893	1	0.053395763	2	0.697705042	2	0	0	0.02877415	0	0.026781704	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Topoisomerase II-associated protein PAT1	Protein PAT1 homolog 2 GN=PATL2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: protein PAT1 homolog 2 [Ceratotherium simum simum]
ENSG00000229544(NKX1-2)	--	0	0	0.0186052	1	0	0	0	0	0.0182527	0	0.0185982	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09309|8.40946e-122|hsa:390010|NKX1-2, C10orf121, NKX-1.1, bB238F13.2; NK1 homeobox 2; K09309 homeobox protein Nkx-1 (A)"	--	[R]	General function prediction only	Homeobox domain	NK1 transcription factor-related protein 2 GN=NKX1-2 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: NK1 transcription factor-related protein 2 [Oryctolagus cuniculus]
ENSG00000229637(PRAC2)	--	0.574202	3	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative protein PRCA2 {ECO:0000305} OS=Homo sapiens (Human) PE=5 SV=1	--	--	PREDICTED: uncharacterized protein LOC103069408 [Lipotes vexillifer]
ENSG00000229809(ZNF688)	--	2.387319994	81	3.291205257	94	3.727181387	86	3.784153063	108	6.535415964	80	3.040453833	95	0.921298302	0.377978565	normal	0.955544582	-0.249726963	normal	0.968045253	0.133072192	normal	0.888057186	0.094970849	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|1.10184e-173|pps:103784244|ZNF688; zinc finger protein 688; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"KRAB box;; Zinc finger, C2H2 type;; Zinc-finger double domain"	Zinc finger protein 688 GN=ZNF688 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 688 isoform X1 [Pantholops hodgsonii]
ENSG00000229833(PET100)	--	20.98906385	188	36.9839693	199	24.44079341	227	30.67457639	226	17.22522001	157	33.027184	164	0.939674724	0.233019116	normal	0.877240251	-0.360339516	normal	0.701910933	-0.473559542	normal	0.624077398	-0.188743888	normal	--	--	--	--	--	--	--	Uncharacterized conserved protein (DUF2346)	"Protein PET100 homolog, mitochondrial (Precursor) GN=PET100 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: protein PET100 homolog, mitochondrial-like, partial [Equus przewalskii]"
ENSG00000229894(GK3P)	--	0.0669833	2	0.0328086	1	0.0328975	0	0.0660933	2	0.0651249	1	0.133053	4	--	--	--	--	--	--	--	--	--	--	--	--	[C]	Energy production and conversion	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: phosphotransferase activity, alcohol group as acceptor (GO:0016773);; "	K00864|0|ptr:739089|GK; glycerol kinase (EC:2.7.1.30); K00864 glycerol kinase [EC:2.7.1.30] (A)	Glycerolipid metabolism (ko00561);; PPAR signaling pathway (ko03320)	[G]	Carbohydrate transport and metabolism	"FGGY family of carbohydrate kinases, N-terminal domain;; FGGY family of carbohydrate kinases, C-terminal domain"	Putative glycerol kinase 3 GN=GK3P OS=Homo sapiens (Human) PE=5 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: glycerol kinase isoform X1 [Ochotona princeps]
ENSG00000229924(FAM90A26)	--	0	0	0.0348348	2	0	0	0.0175658	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Zinc knuckle	Putative protein FAM90A23P GN=FAM90A23P OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	Putative protein FAM90A23 [Tupaia chinensis]
ENSG00000230124(ACBD6)	--	36.8175	1168	31.8579	1034	31.716	1034	31.2002	1004	39.0514	1243	32.1898	1033	0.94092129	-0.248759897	normal	0.944910427	0.243837907	normal	0.979961801	-0.009673219	normal	0.999953667	-0.001602215	normal	[I]	Lipid transport and metabolism	Molecular Function: fatty-acyl-CoA binding (GO:0000062);; Molecular Function: protein binding (GO:0005515);; 	--	--	[I]	Lipid transport and metabolism	Ankyrin repeats (many copies);; Acyl CoA binding protein;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat	Acyl-CoA-binding domain-containing protein 6 GN=ACBD6 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: acyl-CoA-binding domain-containing protein 6 isoform X1 [Galeopterus variegatus]
ENSG00000230257(NFE4)	--	0	0	0	0	0	0	0	0	0	0	0.0679144	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transcription factor NF-E4 GN=NFE4 OS=Homo sapiens (Human) PE=1 SV=1	--	--	--
ENSG00000230453(ANKRD18B)	--	10.79970969	321	9.304368574	316	4.66520487	369	30.21016076	321	10.55835579	257	2.997787404	264	0.967753226	-0.030685392	normal	0.885676386	-0.317892427	normal	0.53258339	-0.488993666	normal	0.304462578	-0.278333725	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Domain of unknown function (DUF3496);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 18B GN=ANKRD18B OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like [Trichechus manatus latirostris]
ENSG00000230510(PPP5D1)	--	0.029924	1	0.173974	1	0	0	0.0629191	1	0.4798612	6	0.11778	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	PPP5 TPR repeat region	Protein PPP5D1 GN=PPP5D1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: serine/threonine-protein phosphatase 5-like, partial [Myotis lucifugus]"
ENSG00000230549(USP17L1)	--	0	0	0	0	0	0	0	0	0	0	0.0341322	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Hyaluronan / mRNA binding family	Putative ubiquitin carboxyl-terminal hydrolase 17-like protein 1 GN=USP17L1P OS=Homo sapiens (Human) PE=5 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 17-like protein 22-like [Ceratotherium simum simum]
ENSG00000230667(SETSIP)	--	0	0	0.136669201	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: nucleus (GO:0005634);; Biological Process: nucleosome assembly (GO:0006334);; 	--	--	[L]	"Replication, recombination and repair"	Nucleosome assembly protein (NAP)	Protein SETSIP GN=SETSIP OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: protein SET isoform 1 [Tursiops truncatus]
ENSG00000230778(ANKRD63)	--	0.368545385	12	0.148183498	5	1.032858	26	0.331468178	11	0.581063	14	0.298660855	10	--	--	--	--	--	--	0.797452564	-1.264420544	normal	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 63 {ECO:0000312|HGNC:HGNC:40027} OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 63 [Orycteropus afer afer]
ENSG00000230797(YY2)	--	2.70037	125	2.70814	124	2.27689	104	2.01598	93	1.72287	79	2.7227	127	0.859489552	-0.451004859	normal	0.523112241	-0.661643965	normal	0.943173261	0.276312049	normal	0.580623712	-0.260129961	normal	[R]	General function prediction only	--	"K09201|0|hsa:404281|YY2, ZNF631; YY2 transcription factor; K09201 transcription factor YY (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger"	Transcription factor YY2 GN=YY2 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: transcription factor YY2-like [Sus scrofa]
ENSG00000230873(STMND1)	--	0	0	0	0	0	0	0.03994319	1	0	0	0.119548749	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: regulation of microtubule polymerization or depolymerization (GO:0031110);; 	--	--	--	--	Stathmin family	Stathmin domain-containing protein 1 GN=STMND1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: stathmin domain-containing protein 1 [Myotis lucifugus]
ENSG00000230989(HSBP1)	--	17.26072017	1754	17.07980012	1894	22.2853002	1825	24.96530025	2360	20.73050025	2187	23.65760017	1965	0.770261474	0.397005104	normal	0.974413412	0.185952067	normal	0.983568627	0.09826292	normal	0.189226543	0.229018641	normal	--	--	--	--	--	[KO]	"Transcription;; Posttranslational modification, protein turnover, chaperones"	Heat shock factor binding protein 1	Heat shock factor-binding protein 1 GN=HSBP1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	heat shock factor-binding protein 1 [Bos taurus] 
ENSG00000231213(PLSCR5)	--	0	0	0	0	0	0	0.0340986	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[M]	Cell wall/membrane/envelope biogenesis	Scramblase	Phospholipid scramblase family member 5 GN=PLSCR5 OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: phospholipid scramblase family member 5 isoform X1 [Oryctolagus cuniculus] 
ENSG00000231256(C17orf105)	--	0	0	0.0997353	7	0.0425349	2	0.0284971	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	KIAA1430 homologue	Uncharacterized protein C17orf105 GN=C17orf105 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C17orf105 homolog [Tupaia chinensis]
ENSG00000231274(SBK3)	--	2.041990682	122	1.909148016	131	1.885486489	113	0.72652442	46	0.606029945	39	1.074084754	69	0.000109363	-1.407972492	down	4.07E-07	-1.730599059	down	0.480710716	-0.707703595	normal	0.000311332	-1.269122186	down	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	--	--	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Uncharacterized serine/threonine-protein kinase SBK3 GN=SBK3 OS=Homo sapiens (Human) PE=3 SV=2	T	Signal transduction mechanisms	PREDICTED: putative uncharacterized serine/threonine-protein kinase SgK110 [Camelus ferus] 
ENSG00000231389(HLA-DPA1)	--	0.053777277	1	0	0	0.086199646	0	0.084586738	1	0.104986059	2	0.035630458	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: immune response (GO:0006955);; Cellular Component: membrane (GO:0016020);; Biological Process: antigen processing and presentation (GO:0019882);; Cellular Component: MHC class II protein complex (GO:0042613);; 	"K06752|1.42197e-136|hsa:3113|HLA-DPA1, DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1; major histocompatibility complex, class II, DP alpha 1; K06752 major histocompatibility complex, class II (A)"	Phagosome (ko04145);; Cell adhesion molecules (CAMs) (ko04514);; Antigen processing and presentation (ko04612);; Intestinal immune network for IgA production (ko04672);; Type I diabetes mellitus (ko04940);; Leishmaniasis (ko05140);; Toxoplasmosis (ko05145);; Staphylococcus aureus infection (ko05150);; Tuberculosis (ko05152);; Influenza A (ko05164);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Asthma (ko05310);; Autoimmune thyroid disease (ko05320);; Inflammatory bowel disease (IBD) (ko05321);; Systemic lupus erythematosus (ko05322);; Rheumatoid arthritis (ko05323);; Allograft rejection (ko05330);; Graft-versus-host disease (ko05332);; Viral myocarditis (ko05416)	--	--	"Class II histocompatibility antigen, alpha domain;; Immunoglobulin C1-set domain"	"HLA class II histocompatibility antigen, DP alpha 1 chain (Precursor) GN=HLA-DPA1 OS=Homo sapiens (Human) PE=1 SV=1"	R	General function prediction only	"PREDICTED: HLA class II histocompatibility antigen, DP alpha 1 chain-like [Trichechus manatus latirostris]"
ENSG00000231500(RPS18)	--	1648.45401	11156	1543.07493	10643	1544.73423	10793	1711.76373	12452	1730.6421	11697	1479.90936	10361	0.995409097	0.127708726	normal	0.995334562	0.114791572	normal	0.996052462	-0.067214506	normal	0.827191176	0.06076144	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	K02964|2.54318e-90|nle:100580186|RPS18; ribosomal protein S18; K02964 small subunit ribosomal protein S18e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S13/S18	40S ribosomal protein S18 GN=RPS18 OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	similar to 40S ribosomal protein S18 [Bos taurus] 
ENSG00000231738(TSPAN19)	--	0.344988834	2	0	0	1.363447469	5	0.165370268	2	0.771321907	5	1.5561325	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K17358|1.29268e-167|hsa:144448|TSPAN19; tetraspanin 19; K17358 tetraspanin-19 (A)	--	[R]	General function prediction only	Tetraspanin family	Putative tetraspanin-19 GN=TSPAN19 OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	PREDICTED: putative tetraspanin-19 [Orcinus orca]
ENSG00000231852(CYP21A2)	--	0	0	0	0	0	0	0.030790701	1	0.0602091	1	0.0305162	1	--	--	--	--	--	--	--	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K00513|0|hsa:1589|CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B; cytochrome P450, family 21, subfamily A, polypeptide 2 (EC:1.14.99.10); K00513 steroid 21-monooxygenase [EC:1.14.99.10] (A)"	Steroid hormone biosynthesis (ko00140)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Steroid 21-hydroxylase GN=CYP21A2 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: steroid 21-hydroxylase-like [Ceratotherium simum simum]
ENSG00000231924(PSG1)	--	0.141458027	5	0.031505559	1	0.078579705	3	0.144227858	5	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06500|0|hsa:5669|PSG1, B1G1, CD66f, DHFRP2, FL-NCA-1/2, PBG1, PS-beta-C/D, PS-beta-G-1, PSBG-1, PSBG1, PSG95, PSGGA, PSGIIA, SP1; pregnancy specific beta-1-glycoprotein 1; K06500 pregnancy specific beta-1-glycoprotein (A)"	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Pregnancy-specific beta-1-glycoprotein 1 (Precursor) GN=PSG1 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1-like [Panthera tigris altaica]
ENSG00000231925(TAPBP)	--	47.59380918	2803	48.7880432	2912	46.73597436	2793	49.00400923	2926	45.68335635	2680	56.28581246	3317	0.989690891	0.031109072	normal	0.984390561	-0.141127486	normal	0.969475334	0.239652788	normal	0.857369958	0.04780323	normal	--	--	--	K08058|0|ggo:101149497|TAPBP; tapasin isoform 1; K08058 TAP binding protein (tapasin) (A)	Antigen processing and presentation (ko04612)	--	--	Immunoglobulin C1-set domain	Tapasin (Precursor) GN=TAPBP OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: tapasin [Ceratotherium simum simum]
ENSG00000232040(ZBED9)	--	0.82771681	79	1.015541438	93	1.083068054	95	0.782715224	71	0.905648907	74	1.412376797	129	0.968213673	-0.181147318	normal	0.937444313	-0.344831066	normal	0.875214041	0.427222657	normal	0.990301572	0.018097116	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	--	--	SCAN domain;; Domain of unknown function (DUF4371);; Integrase core domain;; hAT family C-terminal dimerisation region	SCAN domain-containing protein 3 GN=ZBED9 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: SCAN domain-containing protein 3 [Galeopterus variegatus]
ENSG00000232070(TMEM253)	--	0.102105	2	0.279399	7	0.118891	2	0.298133	3	0.08528714	1	0.195135	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 253 GN=TMEM253 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 253 [Equus caballus]
ENSG00000232112(TMA7)	--	98.963	745	108.907	854	104.075	818	137.984	1080	114.595	854	109.178	837	0.321020818	0.504019027	normal	0.977030004	-0.021388683	normal	0.977180264	0.024790029	normal	0.412165211	0.175156949	normal	--	--	--	--	--	--	--	Translation machinery associated TMA7	--	--	--	--
ENSG00000232119(MCTS1)	--	47.602029	651	49.536641	680	51.463596	702	64.84511	910	55.28813	755	50.18941	695	0.540865667	0.451471856	normal	0.967279453	0.129242477	normal	0.975252596	-0.022700346	normal	0.364496697	0.193214085	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; 	K07575|1.6323e-132|ngi:103734859|Mcts1; malignant T cell amplified sequence 1; K07575 PUA domain protein (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	PUA domain	Malignant T-cell-amplified sequence 1 GN=MCTS1 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: malignant T-cell-amplified sequence 1 isoform X1 [Ursus maritimus]
ENSG00000232196(MTRNR2L4)	--	0.0662254	2	0.132921	4	0.098652	2	0.227675	7	0.127183	3	0.12968	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Humanin-like 4 {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=1	--	--	--
ENSG00000232237(ASCL5)	--	0.2668039	6	0.416071976	8	0.401798656	7	0.2025584	6	0.151783	4	0.276844238	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	"K09067|2.61114e-92|hsa:647219|ASCL5, bHLHa47; achaete-scute family bHLH transcription factor 5; K09067 achaete-scute complex protein (A)"	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Achaete-scute homolog 5 GN=ASCL5 OS=Homo sapiens (Human) PE=3 SV=2	K	Transcription	PREDICTED: achaete-scute homolog 5 [Condylura cristata]
ENSG00000232593(KANTR)	--	0.30547195	15	2.126128	1177	0.46177812	21	0.30224808	15	0.4286912	127	0.45788408	128	--	--	--	0	-3.21827531	down	2.18E-12	2.516339844	up	0.65663355	-2.187740197	normal	--	--	--	--	--	--	--	--	Endonuclease OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	"hypothetical protein M91_12051, partial [Bos mutus]"
ENSG00000232653(GOLGA8N)	--	3.333757971	331	2.465442416	244	2.70163455	266	2.333854132	232	2.431426511	240	2.286949332	227	0.390223882	-0.540524306	normal	0.965190845	-0.044992125	normal	0.93620837	-0.235573985	normal	0.321035742	-0.288113169	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8N OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: golgin subfamily A member 2-like [Pteropus alecto]
ENSG00000233024(RP11-1212A22.4)	--	0.106083669	3	0.105282886	3	0.071236823	1	0.035825554	1	0	0	0.035832076	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A5 GN=NPIPA5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000233041(PHGR1)	--	0	0	0.388263	1	0.748738	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000233198(RNF224)	--	0.703406	25	0.780227	27	0.597578	21	0.293218	10	0.358177	13	1.121744	40	0.836900891	-1.22966169	normal	0.900363064	-0.99405099	normal	0.848462606	0.87496384	normal	0.877048232	-0.230039254	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 224 GN=RNF224 OS=Homo sapiens (Human) PE=3 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: RING finger protein 224 [Physeter catodon]
ENSG00000233276(GPX1)	--	235.49509	2822	197.04938	2410	241.813379	2989	262.692002	3229	249.382284	2993	231.00588	2796	0.983349396	0.163453952	normal	0.945104252	0.290968462	normal	0.987482218	-0.104535282	normal	0.6027583	0.112140791	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: glutathione peroxidase activity (GO:0004602);; Biological Process: response to oxidative stress (GO:0006979);; Biological Process: oxidation-reduction process (GO:0055114);; 	K00432|2.48601e-136|ptr:461015|GPX1; glutathione peroxidase 1 (EC:1.11.1.9); K00432 glutathione peroxidase [EC:1.11.1.9] (A)	Glutathione metabolism (ko00480);; Arachidonic acid metabolism (ko00590);; Thyroid hormone synthesis (ko04918)	[O]	"Posttranslational modification, protein turnover, chaperones"	Glutathione peroxidase	Glutathione peroxidase 1 GN=GPX1 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	glutathione peroxidase 1 [Equus caballus]
ENSG00000233436(BTBD18)	--	0.030315515	2	0.045157245	3	0	0	0.07588972	5	0.073798992	4	0.015028681	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TR]	Signal transduction mechanisms;; General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein 18 GN=BTBD18 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: BTB/POZ domain-containing protein 18 [Dasypus novemcinctus]
ENSG00000233493(TMEM238)	--	14.6443	148	15.0912	159	14.7219	159	17.4986	180	19.6639	201	16.5723	170	0.939870255	0.249218617	normal	0.908227981	0.314080079	normal	0.964840366	0.087412366	normal	0.576463471	0.220490388	normal	--	--	--	--	--	--	--	TMEM238 protein family	Transmembrane protein 238 GN=TMEM238 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 238 [Lipotes vexillifer]
ENSG00000233608(TWIST2)	--	15.66950113	284	14.38646321	260	12.31157892	258	8.521973452	150	8.298043132	161	7.318485598	148	0.001011433	-0.944602949	normal	0.088992006	-0.707594837	normal	0.020097779	-0.80376414	normal	0.00080552	-0.826368434	normal	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	K09069|7.64152e-114|ssc:100519927|TWIST2; twist basic helix-loop-helix transcription factor 2; K09069 twist (A)	Proteoglycans in cancer (ko05205)	[K]	Transcription	Helix-loop-helix DNA-binding domain	Twist-related protein 2 GN=TWIST2 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: twist-related protein 2 [Oryctolagus cuniculus] 
ENSG00000233757(AC092835.2)	--	0.719762	92	0.776391121	101	0.605029578	74	0.553747779	72	0.6933176	86	0.54774967	71	0.931524888	-0.377325977	normal	0.953550803	-0.249322724	normal	0.973582807	-0.066607889	normal	0.660985852	-0.243095778	normal	[R]	General function prediction only	--	K09228|0|ggo:101146342|zinc finger protein 470-like; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain;; Transposase zinc-ribbon domain"	Zinc finger protein 570 GN=ZNF570 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 286A-like isoform X2 [Canis lupus familiaris]
ENSG00000233822(HIST1H2BN)	--	1.098430337	18	0.944706738	27	1.24653844	37	1.21100243	31	1.465562893	25	1.604053476	25	0.952666813	0.706996049	normal	0.984837188	-0.125169895	normal	0.959162034	-0.54654983	normal	0.985893701	-0.038740537	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|1.11702e-86|ptr:462508|histone H2B type 1-N; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-C/E/F/G/I GN=HIST1H2BI OS=Homo sapiens (Human) PE=1 SV=4	B	Chromatin structure and dynamics	PREDICTED: histone H2B type 1-like [Physeter catodon]
ENSG00000233927(RPS28)	--	169.309619	3458	171.4472386	3567	181.8672097	3751	195.5490926	4029	175.5648754	3556	188.143247	3833	0.982816171	0.189573586	normal	0.991044331	-0.025871464	normal	0.991731368	0.02289816	normal	0.80458614	0.062209699	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02979|1.5051e-31|nle:100602422|40S ribosomal protein S28-like; K02979 small subunit ribosomal protein S28e (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein S28e	40S ribosomal protein S28 GN=RPS28 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: 40S ribosomal protein S28 [Orcinus orca]
ENSG00000233954(UQCRHL)	--	0.0470889	2	0.210514	9	0.0924808	3	0.0234077	1	0.114362	4	0.0929747	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K00416|3.28535e-51|hsa:440567|UQCRHL; ubiquinol-cytochrome c reductase hinge protein-like; K00416 ubiquinol-cytochrome c reductase subunit 6 (A)	Oxidative phosphorylation (ko00190);; Cardiac muscle contraction (ko04260);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	Ubiquinol-cytochrome C reductase hinge protein	"Cytochrome b-c1 complex subunit 6, mitochondrial (Precursor) GN=UQCRH OS=Homo sapiens (Human) PE=1 SV=2"	C	Energy production and conversion	"PREDICTED: cytochrome b-c1 complex subunit 6, mitochondrial [Oryctolagus cuniculus]"
ENSG00000234127(TRIM26)	--	9.78112678	742	9.992409817	754	9.981930462	734	11.89378998	851	10.98346086	802	10.54043794	800	0.962777446	0.166585416	normal	0.974195596	0.067479916	normal	0.970507888	0.115700098	normal	0.632235429	0.116076962	normal	--	--	Molecular Function: protein binding (GO:0005515);; Cellular Component: intracellular (GO:0005622);; Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	K12008|0|pps:100985403|TRIM26; tripartite motif containing 26; K12008 tripartite motif-containing protein 26 (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; SPRY-associated domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; B-box zinc finger;; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	Tripartite motif-containing protein 26 GN=TRIM26 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tripartite motif-containing protein 26 [Galeopterus variegatus]
ENSG00000234284(ZNF879)	--	0.734666025	52	0.967605	38	1.065531	60	1.0072776	39	0.699021908	34	0.848639939	55	0.955630896	-0.431107057	normal	0.979629992	-0.17454339	normal	0.974942683	-0.130388617	normal	0.730012906	-0.248413648	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:345462|ZNF879, DKFZp686E2433; zinc finger protein 879; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; Transposase zinc-ribbon domain"	Zinc finger protein 879 GN=ZNF879 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 879 [Ceratotherium simum simum]
ENSG00000234409(CCDC188)	--	0.140984	4	0.233717	7	0.0325028	0	0.0342044	1	0	0	0.102349	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMCO5 family	--	S	Function unknown	PREDICTED: uncharacterized protein LOC102150044 [Equus caballus]
ENSG00000234444(ZNF736)	--	0.393860707	42	0.575897666	64	0.412584922	47	0.208345785	23	0.190357102	12	0.127134238	14	0.839993749	-0.856619593	normal	5.53E-06	-2.297474099	down	0.023675288	-1.652696785	normal	0.001043547	-1.666046568	down	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:728927|ZNF736; zinc finger protein 736; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 736 GN=ZNF736 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000234465(PINLYP)	--	0	0	0	0	0.188184059	0	0.193519014	1	0.121389	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: phospholipase inhibitor activity (GO:0004859);; Cellular Component: extracellular region (GO:0005576);; 	--	--	--	--	u-PAR/Ly-6 domain;; Phospholipase A2 inhibitor	phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein (Precursor) GN=PINLYP OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein [Condylura cristata]
ENSG00000234545(FAM133B)	--	13.62773414	508	14.79069	544	12.29874701	459	13.7163781	529	14.66090342	547	13.15800598	495	0.971765453	0.027525382	normal	0.971903986	-0.013455076	normal	0.966622047	0.100324569	normal	0.921405102	0.034576779	normal	--	--	--	--	--	--	--	--	Protein FAM133B GN=FAM133B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM133B-like [Tupaia chinensis]
ENSG00000234602(MCIDAS)	--	1.316892593	69	1.098691109	50	1.40109568	67	1.2005176	62	0.789407673	41	1.064496764	53	0.970768701	-0.180908108	normal	0.968888207	-0.297767666	normal	0.956806107	-0.337866211	normal	0.66906587	-0.275347257	normal	--	--	Biological Process: regulation of DNA replication (GO:0006275);; 	"K10749|0|hsa:345643|MCIDAS, IDAS, MCI, MCIN; multiciliate differentiation and DNA synthesis associated cell cycle protein; K10749 geminin (A)"	--	--	--	Geminin	Multicilin GN=MCIDAS OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: multicilin [Odobenus rosmarus divergens]
ENSG00000234616(JRK)	--	5.428502178	849	6.304280222	947	5.313208442	803	5.387917693	869	4.964434583	726	4.748133302	752	0.977772788	0.002754433	normal	0.715549886	-0.404082055	normal	0.972075466	-0.102758746	normal	0.434794417	-0.16905414	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; 	--	--	[BD]	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	DDE superfamily endonuclease;; CENP-B N-terminal DNA-binding domain;; Tc5 transposase DNA-binding domain	Jerky protein homolog GN=JRK OS=Homo sapiens (Human) PE=1 SV=2	BD	"Chromatin structure and dynamics;; Cell cycle control, cell division, chromosome partitioning"	PREDICTED: jerky protein homolog [Galeopterus variegatus]
ENSG00000234719(NPIPB2)	--	8.605672063	111	7.512586462	99	10.12743752	134	8.82816923	113	7.166338262	95	9.424563743	114	0.969974483	-0.005000568	normal	0.968403619	-0.079684846	normal	0.949551633	-0.238568247	normal	0.84006498	-0.116115115	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Putative NPIP-like protein LOC729978 OS=Homo sapiens (Human) PE=5 SV=4	S	Function unknown	--
ENSG00000234965(SHISA8)	--	0.231153	4	0.112349	2	0.158975621	2	0.507624	6	0.2612525	1	0.27735109	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Wnt and FGF inhibitory regulator	Putative protein shisa-8 (Precursor) GN=SHISA8 OS=Homo sapiens (Human) PE=5 SV=2	S	Function unknown	PREDICTED: putative protein shisa-8 [Chrysochloris asiatica]
ENSG00000235034(C19orf81)	--	11.05370046	56	11.593279	64	17.505964	85	10.26822029	49	12.728893	60	10.444505	56	0.972929162	-0.217103715	normal	0.97319969	-0.111806769	normal	0.81204554	-0.597144789	normal	0.568862345	-0.333255472	normal	--	--	--	--	--	--	--	--	Putative uncharacterized protein C19orf81 GN=C19orf81 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: putative uncharacterized protein C19orf81 homolog [Tupaia chinensis] 
ENSG00000235098(ANKRD65)	--	0.0246308	1	0.044910394	1	0.184071061	4	0.062398906	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 65 GN=ANKRD65 OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: ankyrin repeat domain-containing protein 65 [Galeopterus variegatus]
ENSG00000235106(LINC00094)	--	9.599130359	558	9.41359	512	10.58445009	579	13.02211	716	10.93639	636	8.590260387	483	0.860696088	0.328063065	normal	0.901106502	0.290684755	normal	0.916326635	-0.269061053	normal	0.67040182	0.132030247	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000235109(ZSCAN31)	--	1.195153302	52	1.870014855	88	1.71361563	56	1.083410849	45	1.1599898	44	2.02852989	64	0.973700689	-0.23204109	normal	0.12358746	-0.996719215	normal	0.972094027	0.17980857	normal	0.515272262	-0.377970129	normal	[R]	General function prediction only	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09230|0|hsa:64288|ZSCAN31, ZNF20-Lp, ZNF310P, ZNF323, dJ874C20.2; zinc finger and SCAN domain containing 31; K09230 SCAN domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; SCAN domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Zinc finger and SCAN domain-containing protein 31 GN=ZSCAN31 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger and SCAN domain-containing protein 31 [Galeopterus variegatus]
ENSG00000235162(C12orf75)	--	62.600892	1075	57.76171256	1019	76.41509011	1335	274.191633	4817	243.698309	4192	249.1469233	4334	0	2.131392473	up	0	2.017458709	up	0	1.689444066	up	9.50E-49	1.939125197	up	--	--	--	--	--	--	--	OCC1 family	Overexpressed in colon carcinoma 1 protein GN=OCC1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: overexpressed in colon carcinoma 1 protein isoform X2 [Equus przewalskii]
ENSG00000235169(SMIM1)	--	2.698922	42	1.915467863	35	2.916535014	35	1.067762987	10	1.422387748	17	0.677791816	6	0.007571334	-1.944258149	down	0.809795305	-1.000006649	normal	0.005152213	-2.288343104	down	0.001720042	-1.784977852	down	--	--	--	--	--	--	--	--	Small integral membrane protein 1 GN=SMIM1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 1 [Galeopterus variegatus]
ENSG00000235173(HGH1)	--	16.3241302	1061	15.0096	965	17.83617	1053	21.67300001	1428	20.639	1393	17.00162069	1196	0.735784821	0.397241659	normal	0.32530221	0.507502489	normal	0.966706778	0.175184292	normal	0.024770128	0.362062017	normal	--	--	--	--	--	[S]	Function unknown	Domain of unknown function (DUF383);; Domain of unknown function (DUF384)	Protein HGH1 homolog GN=HGH1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein FAM203A [Eptesicus fuscus]
ENSG00000235376(RPEL1)	--	0.234095	7	0.330302	10	0.232527	6	0.0329297	1	0.064838	1	0.0996598	3	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	"Biological Process: carbohydrate metabolic process (GO:0005975);; Molecular Function: racemase and epimerase activity, acting on carbohydrates and derivatives (GO:0016857);; "	K01783|1.83713e-170|hsa:729020|RPEL1; ribulose-5-phosphate-3-epimerase-like 1 (EC:5.1.3.1); K01783 ribulose-phosphate 3-epimerase [EC:5.1.3.1] (A)	Pentose phosphate pathway (ko00030);; Pentose and glucuronate interconversions (ko00040);; Carbon metabolism (ko01200);; Biosynthesis of amino acids (ko01230)	[G]	Carbohydrate transport and metabolism	Ribulose-phosphate 3 epimerase family	Ribulose-phosphate 3-epimerase-like protein 1 GN=RPEL1 OS=Homo sapiens (Human) PE=2 SV=1	G	Carbohydrate transport and metabolism	PREDICTED: ribulose-phosphate 3-epimerase isoform X1 [Ochotona princeps] 
ENSG00000235387(SPAAR)	--	0	0	0.081342361	2	0	0	0	0	0.040099052	0	0.121875862	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	hypothetical protein MDA_GLEAN10021590 [Myotis davidii]
ENSG00000235453(TOPORS-AS1)	--	4.6629753	49	5.298216	35	9.033186	52	5.2086326	54	4.227336	54	7.747962	62	0.97760911	0.106173482	normal	0.91476257	0.583734104	normal	0.969307409	0.239089959	normal	0.648637006	0.301599367	normal	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: uncharacterized protein LOC101107502 [Ovis aries]
ENSG00000235568(NFAM1)	--	0.00820304	1	0	0	0	0	0.008238	1	0.0160411	1	0.00813242	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	NFAT activation molecule 1 (Precursor) GN=NFAM1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: NFAT activation molecule 1 [Balaenoptera acutorostrata scammoni]
ENSG00000235631(RNF148)	--	0.0902633	1	0	0	0	0	0	0	0.0489275	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; PA domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 148 (Precursor) GN=RNF148 OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 148 [Pteropus alecto] 
ENSG00000235750(KIAA0040)	--	0.9246811	75	0.344550923	29	0.207689838	16	0.641411081	56	0.925046368	79	0.799352009	55	0.92747016	-0.441781747	normal	0.006405599	1.379124288	up	0.006216225	1.682374526	up	0.493477005	0.640548234	normal	--	--	--	--	--	--	--	--	Uncharacterized protein KIAA0040 GN=KIAA0040 OS=Homo sapiens (Human) PE=2 SV=1	--	--	"PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein KIAA0040-like, partial [Camelus bactrianus]"
ENSG00000235863(B3GALT4)	--	0.647035	18	0.727482	21	0.746796	21	0.320352	9	0.417848	11	0.425015	12	--	--	--	0.959718243	-0.866779419	normal	0.971898459	-0.743989693	normal	--	--	--	--	--	Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; 	"K00715|0|ptr:746800|B3GALT4; UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4; K00715 ganglioside galactosyltransferase [EC:2.4.1.62] (A)"	Other types of O-glycan biosynthesis (ko00514);; Glycosphingolipid biosynthesis - ganglio series (ko00604)	[G]	Carbohydrate transport and metabolism	Galactosyltransferase	"Beta-1,3-galactosyltransferase 4 GN=B3GALT4 OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: beta-1,3-galactosyltransferase 4 [Galeopterus variegatus] "
ENSG00000235961(PNMA6A)	--	3.42113	134	3.85475	159	2.90733	120	3.92559	157	3.75479	146	4.62536	183	0.954304536	0.195625537	normal	0.959303544	-0.143064401	normal	0.483113631	0.594408815	normal	0.614017522	0.21366401	normal	--	--	--	--	--	--	--	PNMA	Putative paraneoplastic antigen-like protein 6D GN=PNMA6D OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	"PREDICTED: paraneoplastic antigen-like protein 6B-like, partial [Panthera tigris altaica]"
ENSG00000236279(CLEC2L)	--	0	0	0	0	1.846940358	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 2 member L GN=CLEC2L OS=Homo sapiens (Human) PE=2 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	"PREDICTED: C-type lectin domain family 2 member L, partial [Camelus bactrianus]"
ENSG00000236287(ZBED5)	--	35.2558635	1366	32.9598164	1226	32.08539602	1220	37.43926738	1407	45.61192026	1740	40.745639	1605	0.983166608	0.011819483	normal	0.434014236	0.483199129	normal	0.771618252	0.386981232	normal	0.073873163	0.297173629	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	--	--	BED zinc finger	Zinc finger BED domain-containing protein 5 GN=ZBED5 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: zinc finger BED domain-containing protein 5 isoform 1 [Ceratotherium simum simum] 
ENSG00000236320(SLFN14)	--	0	0	0	0	0.0499958	2	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ATP binding (GO:0005524);; 	--	--	--	--	Divergent AAA domain	Schlafen family member 14 GN=SLFN14 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: schlafen family member 14 [Equus przewalskii]
ENSG00000236334(PPIAL4G)	--	0.0154891	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	"K12738|3.43709e-118|hsa:644591|PPIAL4G, COAS-2; peptidylprolyl isomerase A (cyclophilin A)-like 4G (EC:5.2.1.8); K12738 peptidylprolyl cis-trans isomerase A-like 4 [EC:5.2.1.8] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase A-like 4G GN=PPIAL4G OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase A-like [Balaenoptera acutorostrata scammoni]
ENSG00000236383(LINC00854)	--	0	0	0.681856	7	0.665054	6	0.184197252	2	0.288181	2	0.1880425	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: mastermind-like protein 2-like isoform X2 [Tupaia chinensis]
ENSG00000236444(UBE2L5P)	--	0.056164696	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: cellular protein modification process (GO:0006464);; Biological Process: protein transport (GO:0015031);; 	K04552|7.59449e-110|mcf:102129776|ubiquitin-conjugating enzyme E2 L3-like; K04552 ubiquitin-conjugating enzyme E2 L3 [EC:6.3.2.19] (A)	Ubiquitin mediated proteolysis (ko04120);; Parkinson's disease (ko05012)	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin-conjugating enzyme;; Prokaryotic E2 family B;; UEV domain;; RWD domain	Ubiquitin-conjugating enzyme E2 L3 GN=UBE2L3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 L3 [Mustela putorius furo]
ENSG00000236446(CT47B1)	--	0.0428237	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cancer/testis gene family 47	Cancer/testis antigen 47B GN=CT47B1 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: cancer/testis antigen 47A-like [Dasypus novemcinctus]
ENSG00000236609(ZNF853)	--	4.263262	339	2.975764	242	3.707881636	311	3.73424422	303	5.479263	436	2.329749556	192	0.9479521	-0.191879232	normal	0.003063876	0.824005962	normal	0.062556659	-0.699726718	normal	0.967999994	0.039953951	normal	[R]	General function prediction only	--	K09228|6.51451e-101|hsa:54753|ZNF853; zinc finger protein 853; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 853 GN=ZNF853 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: zinc finger protein 853 [Canis lupus familiaris]
ENSG00000236699(ARHGEF38)	--	0	0	0	0	0.06074	5	0	0	0.0195003	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Molecular Function: protein binding (GO:0005515);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain;; BAR domain;; Variant SH3 domain;; Variant SH3 domain;; SH3 domain	Rho guanine nucleotide exchange factor 38 GN=ARHGEF38 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: dynamin-binding protein [Panthera tigris altaica]
ENSG00000236782(RP11-96L14.7)	--	0.045948333	1	0	0	0	0	0	0	0	0	0.045075084	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: uncharacterized protein LOC101903355 isoform X3 [Bos taurus] 
ENSG00000237172(B3GNT9)	--	10.6133	500	10.3257	498	9.32414	455	7.38665	352	9.53385	449	9.48376	453	0.298649876	-0.535213594	normal	0.954698843	-0.170311873	normal	0.970815252	-0.01459831	normal	0.332686849	-0.233050183	normal	--	--	"Biological Process: protein glycosylation (GO:0006486);; Molecular Function: galactosyltransferase activity (GO:0008378);; Cellular Component: membrane (GO:0016020);; Molecular Function: transferase activity, transferring glycosyl groups (GO:0016757);; "	"K18705|0|hsa:84752|B3GNT9; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9; K18705 beta-1,3-N-acetylglucosaminyltransferase 9 [EC:2.4.1.-] (A)"	--	[G]	Carbohydrate transport and metabolism	Galactosyltransferase;; Fringe-like	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 {ECO:0000312|HGNC:HGNC:28714} OS=Homo sapiens (Human) PE=2 SV=1"	G	Carbohydrate transport and metabolism	"PREDICTED: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 [Galeopterus variegatus]"
ENSG00000237190(CDKN2AIPNL)	--	39.28591	612	34.535799	554	38.7254	609	35.998423	574	38.285103	595	32.359216	506	0.966209298	-0.122994256	normal	0.969554684	0.081362799	normal	0.912710745	-0.274846399	normal	0.704388365	-0.105066423	normal	--	--	--	--	--	--	--	Protein of unknown function (DUF3469)	CDKN2AIP N-terminal-like protein GN=CDKN2AIPNL OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: CDKN2AIP N-terminal-like protein-like [Elephantulus edwardii]
ENSG00000237289(CKMT1B)	--	0.158361709	5	0.309923593	10	0.06118002	1	0.09413237	3	0.0919068	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	"Molecular Function: kinase activity (GO:0016301);; Molecular Function: transferase activity, transferring phosphorus-containing groups (GO:0016772);; "	"K00933|0|pon:100435206|creatine kinase U-type, mitochondrial; K00933 creatine kinase [EC:2.7.3.2] (A)"	Arginine and proline metabolism (ko00330)	[C]	Energy production and conversion	"ATP:guanido phosphotransferase, C-terminal catalytic domain;; ATP:guanido phosphotransferase, N-terminal domain"	"Creatine kinase U-type, mitochondrial (Precursor) GN=CKMT1B OS=Homo sapiens (Human) PE=1 SV=1"	C	Energy production and conversion	"PREDICTED: creatine kinase U-type, mitochondrial isoform 1 [Canis lupus familiaris]"
ENSG00000237330(RNF223)	--	0.181441	6	0.118288	4	0.257952	8	0.090066	3	0.0292601	0	0.118462	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 223 GN=RNF223 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 223 [Orycteropus afer afer]
ENSG00000237353(PATE4)	--	0	0	0.094257118	3	0.062426484	1	0	0	0	0	0.124233556	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Prostate and testis expressed protein 4 (Precursor) GN=PATE4 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: prostate and testis expressed protein 4 [Galeopterus variegatus]
ENSG00000237412(PRSS56)	--	0.05758258	2	0	0	0	0	0	0	0.0278118	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	--	--	--	--	Trypsin	Serine protease 56 (Precursor) GN=PRSS56 OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: serine protease 56 [Vicugna pacos]
ENSG00000237440(ZNF737)	--	0.332093447	17	0.395419407	20	0.74237252	20	0.3582426	17	0.946896677	15	0.916852235	17	--	--	--	0.985028201	-0.401313304	normal	0.988216208	-0.224339101	normal	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; SprT-like family;; Zinc ribbon domain;; C1-like domain;; Transposase zinc-ribbon domain"	Zinc finger protein 737 GN=ZNF737 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000237441(RGL2)	--	7.607023	433	7.172916	446	8.213037	513	7.836	392	7.80702	414	8.5701	433	0.953399797	-0.173697491	normal	0.961381568	-0.128387518	normal	0.925851594	-0.252073384	normal	0.468744001	-0.188584854	normal	--	--	Molecular Function: guanyl-nucleotide exchange factor activity (GO:0005085);; Biological Process: signal transduction (GO:0007165);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	K17636|0|ggo:101146057|RGL2; ral guanine nucleotide dissociation stimulator-like 2 isoform 1; K17636 ral guanine nucleotide dissociation stimulator-like 2 (A)	Ras signaling pathway (ko04014)	[T]	Signal transduction mechanisms	RasGEF domain;; RasGEF N-terminal motif;; Ras association (RalGDS/AF-6) domain	Ral guanine nucleotide dissociation stimulator-like 2 GN=RGL2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ral guanine nucleotide dissociation stimulator-like 2 [Ursus maritimus]
ENSG00000237452(BHMG1)	--	0.0624155	4	0	0	0	0	0.015672	1	0.121149	7	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[K]	Transcription	HMG (high mobility group) box;; Helix-loop-helix DNA-binding domain	Basic helix-loop-helix and HMG box domain-containing protein 1 {ECO:0000312|HGNC:HGNC:44318} OS=Homo sapiens (Human) PE=3 SV=2	K	Transcription	PREDICTED: uncharacterized protein LOC102152693 [Canis lupus familiaris]
ENSG00000237489(LINC00959)	--	0.729954	9	0.308114	4	0.845043	10	0.158748	2	0.158256	1	0.400776	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC100511352 isoform X1 [Sus scrofa]
ENSG00000237515(SHISA9)	--	0.4470477	52	0.4606439	55	0.4628393	56	0.595636586	70	0.6890798	81	0.4661487	55	0.947657227	0.388098133	normal	0.878984686	0.525100862	normal	0.977396057	-0.033377123	normal	0.595179408	0.316125082	normal	--	--	--	--	--	--	--	Wnt and FGF inhibitory regulator	Protein shisa-9 (Precursor) GN=SHISA9 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: protein shisa-9 [Equus caballus]
ENSG00000237649(KIFC1)	--	19.546603	1019	14.4520366	913	15.88319072	1006	16.21891011	964	17.67265833	914	13.9493474	812	0.974406015	-0.110709604	normal	0.977863665	-0.019814451	normal	0.881537417	-0.316838904	normal	0.495439551	-0.148820596	normal	[Z]	Cytoskeleton	Molecular Function: microtubule motor activity (GO:0003777);; Molecular Function: ATP binding (GO:0005524);; Biological Process: microtubule-based movement (GO:0007018);; Molecular Function: microtubule binding (GO:0008017);; 	"K10405|0|hsa:3833|KIFC1, HSET, KNSL2; kinesin family member C1; K10405 kinesin family member C1 (A)"	--	[Z]	Cytoskeleton	Kinesin motor domain	Kinesin-like protein KIFC1 GN=KIFC1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: kinesin-like protein KIFC1 [Galeopterus variegatus]
ENSG00000237651(C2orf74)	--	11.21176611	171	9.498813039	158	9.980366	173	5.229751815	102	7.320924512	110	5.821908906	112	0.119176801	-0.767228483	normal	0.679716635	-0.537644569	normal	0.415795153	-0.628680426	normal	0.041528745	-0.65247419	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4642)	Uncharacterized protein C2orf74 GN=C2orf74 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: uncharacterized protein C2orf74 homolog [Tupaia chinensis]
ENSG00000237765(FAM200B)	--	6.98377814	244	6.174208298	236	8.278931088	265	7.983624966	291	5.856940412	219	7.331136837	245	0.939822825	0.222024327	normal	0.958779224	-0.128427977	normal	0.960819728	-0.120784974	normal	1	-0.00241696	normal	--	--	--	--	--	--	--	BED zinc finger	Putative protein FAM200B GN=FAM200B OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	PREDICTED: putative protein FAM200B [Ceratotherium simum simum]
ENSG00000238083(LRRC37A2)	--	1.18504707	152	1.318589	161	1.18313	147	1.0866094	138	1.0298847	131	1.30649	164	0.958339805	-0.168447385	normal	0.917626488	-0.31562726	normal	0.9599567	0.148144677	normal	0.830610436	-0.108093225	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	LRRC37A/B like protein 1 C-terminal domain;; Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat	Leucine-rich repeat-containing protein 37A2 (Precursor) GN=LRRC37A2 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: leucine-rich repeat-containing protein 37A-like [Pteropus alecto]
ENSG00000238227(C9orf69)	--	30.99979404	1478	33.97171193	1649	30.64190585	1528	33.11300823	1581	33.50590101	1589	40.62910687	1941	0.982863532	0.0662922	normal	0.98275078	-0.074828917	normal	0.88124612	0.336567912	normal	0.599269878	0.114171072	normal	--	--	--	--	--	[DZU]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton;; Intracellular trafficking, secretion, and vesicular transport"	--	Protein C9orf69 GN=C9orf69 OS=Homo sapiens (Human) PE=1 SV=2	DUZ	"Cell cycle control, cell division, chromosome partitioning;; Intracellular trafficking, secretion, and vesicular transport;; Cytoskeleton"	PREDICTED: protein C9orf69 homolog [Echinops telfairi]
ENSG00000239264(TXNDC5)	--	92.86300109	5050	85.86121202	4739	86.72772701	4778	102.5780021	5625	100.899498	5475	90.39203345	4942	0.991384818	0.124701486	normal	0.98652259	0.186794251	normal	0.993028057	0.040384146	normal	0.593867485	0.117563664	normal	[OC]	"Posttranslational modification, protein turnover, chaperones;; Energy production and conversion"	Biological Process: cell redox homeostasis (GO:0045454);; 	K13984|0|ptr:100615889|TXNDC5; thioredoxin domain containing 5 (endoplasmic reticulum); K13984 thioredoxin domain-containing protein 5 (A)	Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Thioredoxin;; Thioredoxin-like domain;; Thioredoxin-like;; Thioredoxin-like;; Redoxin	Thioredoxin domain-containing protein 5 (Precursor) GN=TXNDC5 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: thioredoxin domain-containing protein 5 [Orcinus orca]
ENSG00000239388(ASB14)	--	0.03800831	2	0.096674262	5	0.0382441	1	0.1521725	8	0.1105454	5	0.01880913	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: intracellular signal transduction (GO:0035556);; 	K10336|0|hsa:142686|ASB14; ankyrin repeat and SOCS box containing 14; K10336 ankyrin repeat and SOCS box protein 14 (A)	--	[R]	General function prediction only	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; SOCS box	Ankyrin repeat and SOCS box protein 14 GN=ASB14 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat and SOCS box protein 14 isoform X2 [Myotis lucifugus]
ENSG00000239521(GATS)	--	11.09638	435	13.6467841	496	12.60493	427	5.8266	232	7.045091	295	6.23762	246	0.000200964	-0.933130881	normal	0.006656367	-0.767979615	normal	0.004385591	-0.800087904	normal	2.18E-05	-0.834034051	normal	--	--	--	--	--	--	--	ACT domain	Putative protein GATS GN=GATS OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	PREDICTED: GATS-like protein 2 [Condylura cristata]
ENSG00000239590(OR1J4)	--	0	0	0	0	0	0	0	0	0.0958691	0	0.09747	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:26219|OR1J4, HSHTPCRX01, HTPCRX01, OR9-21; olfactory receptor, family 1, subfamily J, member 4; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 1J4 GN=OR1J4 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 1J4-like [Chrysochloris asiatica]
ENSG00000239605(C2orf61)	--	0.074657603	1	0	0	0	0	0.073633004	1	0.0630488	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf61 GN=C2orf61 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C2orf61 homolog [Ceratotherium simum simum]
ENSG00000239713(APOBEC3G)	--	0	0	0.113181	4	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	"K18750|0|hsa:60489|APOBEC3G, A3G, ARCD, ARP-9, ARP9, CEM-15, CEM15, bK150C2.7, dJ494G10.1; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G (EC:3.5.4.5); K18750 C->U-editing enzyme APOBEC3 [EC:3.5.4.-] (A)"	--	--	--	APOBEC-like N-terminal domain;; APOBEC-like C-terminal domain	DNA dC-	L	"Replication, recombination and repair"	PREDICTED: DNA dC-
ENSG00000239779(WBP1)	--	56.956084	1165	47.89389	1004	51.020572	1073	36.98221	757	39.19238	791	39.550762	819	0.021161887	-0.651721688	normal	0.810589478	-0.364815504	normal	0.726599301	-0.397363103	normal	0.002682042	-0.474754752	normal	--	--	--	--	--	--	--	WW domain-binding protein 1	WW domain-binding protein 1 GN=WBP1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: WW domain-binding protein 1 isoform X2 [Oryctolagus cuniculus]
ENSG00000239857(GET4)	--	31.1859968	1065	27.32120078	1071	25.80023	953	28.454804	1053	31.35965524	1148	33.79567	1229	0.979399119	-0.047111904	normal	0.978010929	0.078630353	normal	0.824262993	0.35814361	normal	0.55303736	0.130156377	normal	--	--	--	--	--	[S]	Function unknown	Protein of unknown function (DUF410)	Golgi to ER traffic protein 4 homolog GN=GET4 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: Golgi to ER traffic protein 4 homolog [Odobenus rosmarus divergens]
ENSG00000239900(ADSL)	--	41.5279562	1308	40.85715	1332	43.80480347	1423	41.44226388	1350	45.538823	1371	33.7382054	1120	0.982682594	0.014747552	normal	0.982401373	0.020185342	normal	0.839580511	-0.35330409	normal	0.651640108	-0.102611695	normal	[F]	Nucleotide transport and metabolism	--	"K01756|0|hsa:158|ADSL, AMPS, ASASE, ASL; adenylosuccinate lyase (EC:4.3.2.2); K01756 adenylosuccinate lyase [EC:4.3.2.2] (A)"	"Purine metabolism (ko00230);; Alanine, aspartate and glutamate metabolism (ko00250)"	[F]	Nucleotide transport and metabolism	Lyase;; Adenylosuccinate lyase C-terminus	Adenylosuccinate lyase GN=ADSL OS=Homo sapiens (Human) PE=1 SV=2	F	Nucleotide transport and metabolism	adenylosuccinate lyase [Sus scrofa] 
ENSG00000240045(RP11-451G4.2)	--	0	0	0	0	0	0	0.0952291	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000240065(PSMB9)	--	12.0622	128	10.0199	111	10.592104	113	15.5275	172	18.4046	194	16.4062	175	0.869593785	0.391367604	normal	0.082321471	0.775977007	normal	0.447406947	0.616065027	normal	0.057416456	0.598907272	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02741|2.44542e-144|hsa:5698|PSMB9, LMP2, PSMB6i, RING12, beta1i; proteasome (prosome, macropain) subunit, beta type, 9 (EC:3.4.25.1); K02741 20S proteasome subunit beta 9 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-9 (Precursor) GN=PSMB9 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: proteasome subunit beta type-9 [Ceratotherium simum simum]
ENSG00000240204(SMKR1)	--	9.08765	166	9.65658	183	6.04777	114	8.83752	164	8.62015	157	9.22869	171	0.966718429	-0.047873885	normal	0.939793457	-0.240358757	normal	0.578625402	0.570451971	normal	0.902244699	0.065835623	normal	--	--	--	--	--	--	--	--	Small lysine-rich protein 1 GN=SMKR1 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: small lysine-rich protein 1 [Tupaia chinensis]
ENSG00000240230(COX19)	--	3.05429	241	3.3865	284	3.21992	247	3.82908	298	4.22196	318	3.94749	321	0.917867823	0.273874427	normal	0.95726031	0.14099947	normal	0.832989024	0.367790165	normal	0.362871703	0.258359305	normal	--	--	--	K18183|9.13649e-59|hsa:90639|COX19; COX19 cytochrome c oxidase assembly factor; K18183 cytochrome c oxidase assembly protein subunit 19 (A)	--	[C]	Energy production and conversion	CHCH domain	Cytochrome c oxidase assembly protein COX19 GN=COX19 OS=Homo sapiens (Human) PE=1 SV=1	C	Energy production and conversion	PREDICTED: cytochrome c oxidase assembly protein COX19-like [Tupaia chinensis]
ENSG00000240344(PPIL3)	--	13.23117901	217	10.95922905	196	14.546727	237	12.26802123	220	11.49261126	195	13.03402932	220	0.966930616	-0.010946807	normal	0.965537592	-0.028584971	normal	0.961507447	-0.114913716	normal	0.90801502	-0.054654189	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Biological Process: protein peptidyl-prolyl isomerization (GO:0000413);; Molecular Function: peptidyl-prolyl cis-trans isomerase activity (GO:0003755);; Biological Process: protein folding (GO:0006457);; 	K12734|1.12804e-116|umr:103659735|PPIL3; peptidylprolyl isomerase (cyclophilin)-like 3; K12734 peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Peptidyl-prolyl cis-trans isomerase-like 3 GN=PPIL3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: peptidyl-prolyl cis-trans isomerase-like 3 [Eptesicus fuscus]
ENSG00000240563(L1TD1)	--	0.0114288	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	L1 transposable element	LINE-1 type transposase domain-containing protein 1 GN=L1TD1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: LINE-1 type transposase domain-containing protein 1-like, partial [Leptonychotes weddellii]"
ENSG00000240694(PNMA2)	--	30.3865	2796	26.3284	2458	30.7084	2835	29.3751	2710	23.2312	2126	22.2887	2052	0.988313745	-0.075861426	normal	0.966295794	-0.230617154	normal	0.487182366	-0.474310712	normal	0.177465779	-0.253827659	normal	--	--	--	--	--	--	--	PNMA;; Retrotransposon gag protein	Paraneoplastic antigen Ma2 GN=PNMA2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: paraneoplastic antigen Ma2 homolog [Equus caballus] 
ENSG00000240771(ARHGEF25)	--	9.92020527	472	7.039999851	347	8.420271942	420	6.354185372	309	7.729246898	375	6.355868047	298	0.072762547	-0.639418786	normal	0.964305044	0.090150384	normal	0.459696072	-0.501215131	normal	0.129983792	-0.356450766	normal	--	--	Molecular Function: Rho guanyl-nucleotide exchange factor activity (GO:0005089);; Biological Process: regulation of Rho protein signal transduction (GO:0035023);; 	--	--	[T]	Signal transduction mechanisms	RhoGEF domain	Rho guanine nucleotide exchange factor 25 GN=ARHGEF25 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho guanine nucleotide exchange factor 25 isoform 1 [Ceratotherium simum simum]
ENSG00000241058(NSUN6)	--	4.26574328	129	5.96351519	133	5.9909053	166	4.874302489	116	3.415113	145	2.786103321	123	0.959169569	-0.181793744	normal	0.963709654	0.102088162	normal	0.828207597	-0.436182463	normal	0.705814122	-0.176989608	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: methyltransferase activity (GO:0008168);; Biological Process: methylation (GO:0032259);; 	--	--	[A]	RNA processing and modification	NOL1/NOP2/sun family;; Methyltransferase domain;; FtsJ-like methyltransferase;; Methyltransferase domain;; Methyltransferase domain	Putative methyltransferase NSUN6 GN=NSUN6 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: putative methyltransferase NSUN6 [Trichechus manatus latirostris]
ENSG00000241127(YAE1D1)	--	12.470333	159	11.82819396	156	12.40523229	163	10.22763546	139	12.30679697	161	11.03128639	146	0.948727785	-0.222472688	normal	0.966152569	0.023860418	normal	0.957846579	-0.16557104	normal	0.802027024	-0.120879959	normal	--	--	--	--	--	[S]	Function unknown	"Essential protein Yae1, N terminal"	Yae1 domain-containing protein 1 GN=YAE1D1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: yae1 domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000241233(KRTAP5-8)	--	0	0	0.133421	2	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized transmembrane protein DDB_G0289901-like [Galeopterus variegatus]
ENSG00000241241(KRTAP4-16)	--	0	0	0	0	0	0	0	0	0	0	0.159466	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: keratin filament (GO:0045095);; 	--	--	--	--	"Keratin, high sulfur B2 protein"	Keratin-associated protein 4-12 GN=KRTAP4-12 OS=Homo sapiens (Human) PE=1 SV=1	--	--	--
ENSG00000241360(PDXP)	--	13.48071999	419	13.15862623	418	15.43414662	495	11.85882085	371	10.23663919	318	9.466686022	297	0.944388095	-0.20556161	normal	0.727401875	-0.414178883	normal	0.009924878	-0.742296914	normal	0.032867937	-0.455522612	normal	[G]	Carbohydrate transport and metabolism	--	"K07758|6.5402e-176|hsa:57026|PDXP, CIN, PLP, dJ37E16.5; pyridoxal (pyridoxine, vitamin B6) phosphatase (EC:3.1.3.3 3.1.3.74); K07758 pyridoxal phosphatase [EC:3.1.3.74] (A)"	Vitamin B6 metabolism (ko00750)	[P]	Inorganic ion transport and metabolism	Haloacid dehalogenase-like hydrolase;; HAD-hyrolase-like;; haloacid dehalogenase-like hydrolase;; Haloacid dehalogenase-like hydrolase	Pyridoxal phosphate phosphatase GN=PDXP OS=Homo sapiens (Human) PE=1 SV=2	P	Inorganic ion transport and metabolism	PREDICTED: pyridoxal phosphate phosphatase [Lipotes vexillifer]
ENSG00000241404(EGFL8)	--	0.865865461	18	1.22677011	27	1.249118936	27	1.252190345	24	0.890564291	18	1.08119041	24	0.984670975	0.357696978	normal	0.970835361	-0.567228958	normal	0.985362064	-0.168217336	normal	0.900535826	-0.146594326	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: protein binding (GO:0005515);; 	--	--	[T]	Signal transduction mechanisms	EMI domain;; EGF-like domain;; Calcium-binding EGF domain	Epidermal growth factor-like protein 8 (Precursor) GN=EGFL8 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: epidermal growth factor-like protein 8 isoform X2 [Galeopterus variegatus]
ENSG00000241644(INMT)	--	0	0	0	0	0	0	0	0	0.02310061	0	0.0471405	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: methyltransferase activity (GO:0008168);; 	"K00562|0|hsa:11185|INMT, TEMT; indolethylamine N-methyltransferase (EC:2.1.1.49 2.1.1.96); K00562 methyltransferase [EC:2.1.1.49 2.1.1.96] (A)"	Tryptophan metabolism (ko00380);; Selenocompound metabolism (ko00450)	--	--	NNMT/PNMT/TEMT family	Indolethylamine N-methyltransferase GN=INMT OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	indolethylamine N-methyltransferase [Oryctolagus cuniculus] 
ENSG00000241878(PISD)	--	9.192306	392	9.855989352	395	9.192717068	402	13.5008167	456	12.22167939	468	14.26512011	553	0.950331324	0.186669091	normal	0.938331131	0.222446148	normal	0.586855283	0.450342224	normal	0.198415788	0.292338329	normal	[I]	Lipid transport and metabolism	Molecular Function: phosphatidylserine decarboxylase activity (GO:0004609);; Biological Process: phospholipid biosynthetic process (GO:0008654);; 	K01613|0|pps:100994857|PISD; phosphatidylserine decarboxylase; K01613 phosphatidylserine decarboxylase [EC:4.1.1.65] (A)	Glycerophospholipid metabolism (ko00564)	[I]	Lipid transport and metabolism	Phosphatidylserine decarboxylase	Phosphatidylserine decarboxylase beta chain GN=PISD OS=Homo sapiens (Human) PE=2 SV=4	I	Lipid transport and metabolism	PREDICTED: phosphatidylserine decarboxylase proenzyme [Orycteropus afer afer]
ENSG00000241945(PWP2)	--	0.076539041	5	0.059481557	4	0.278835395	4	0.106458012	7	0.0595475	3	0.0303463	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K14558|0|hsa:5822|PWP2, EHOC-17, PWP2H, UTP1; PWP2 periodic tryptophan protein homolog (yeast); K14558 periodic tryptophan protein 2 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[A]	RNA processing and modification	"WD domain, G-beta repeat;; Dip2/Utp12 Family;; Eukaryotic translation initiation factor eIF2A"	Periodic tryptophan protein 2 homolog GN=PWP2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: periodic tryptophan protein 2 homolog isoform X1 [Tupaia chinensis] 
ENSG00000241973(PI4KA)	--	7.884802216	1134	9.135712352	1281	8.515981708	1231	8.513485446	1219	8.474848126	1215	10.42479982	1455	0.979459253	0.073349362	normal	0.978209076	-0.097622363	normal	0.95343096	0.232633792	normal	0.772951985	0.072418658	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: kinase activity (GO:0016301);; 	"K00888|0|hsa:5297|PI4KA, PI4K-ALPHA, PIK4CA, pi4K230; phosphatidylinositol 4-kinase, catalytic, alpha (EC:2.7.1.67); K00888 phosphatidylinositol 4-kinase [EC:2.7.1.67] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070)	[T]	Signal transduction mechanisms	"Phosphatidylinositol 3- and 4-kinase;; Phosphoinositide 3-kinase family, accessory domain (PIK domain)"	Phosphatidylinositol 4-kinase alpha GN=PI4KA OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 4-kinase alpha isoform X2 [Galeopterus variegatus]
ENSG00000242110(AMACR)	--	12.51987275	447	9.572735	376	10.94986786	399	11.02071204	403	11.98888813	424	13.3203354	432	0.952166277	-0.179676426	normal	0.957052206	0.151331622	normal	0.964769524	0.105965055	normal	0.960928484	0.022049931	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; 	"K01796|0|hsa:23600|AMACR, AMACRD, CBAS4, RACE, RM; alpha-methylacyl-CoA racemase (EC:5.1.99.4); K01796 alpha-methylacyl-CoA racemase [EC:5.1.99.4] (A)"	Primary bile acid biosynthesis (ko00120);; Peroxisome (ko04146)	[I]	Lipid transport and metabolism	CoA-transferase family III	Alpha-methylacyl-CoA racemase GN=AMACR OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: alpha-methylacyl-CoA racemase [Bos taurus] 
ENSG00000242180(OR51B5)	--	0.108312	1	0	0	0	0	0.107441	1	0.105675	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:282763|OR51B5, HOR5'Beta5, OR11-37; olfactory receptor, family 51, subfamily B, member 5; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Olfactory receptor 51B5 GN=OR51B5 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 51B5-like [Myotis davidii] 
ENSG00000242259(C22orf39)	--	8.950589312	285	10.37237696	292	9.401954931	287	10.694215	342	10.256782	294	9.32099947	289	0.93549407	0.231063827	normal	0.966679702	-0.011519317	normal	0.967689009	0.001718291	normal	0.840002795	0.076663029	normal	--	--	--	--	--	--	--	--	UPF0545 protein C22orf39 GN=C22orf39 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: UPF0545 protein C22orf39 homolog [Mustela putorius furo] 
ENSG00000242265(PEG10)	--	66.5504	8296	55.02446	6857	73.0916	9037	37.38473	4674	33.74874	4193	50.19112	6326	4.10E-05	-0.858375498	normal	0.003390268	-0.730812929	normal	0.403986887	-0.522736682	normal	0.004552243	-0.6909589	normal	--	--	--	--	--	--	--	Retrotransposon gag protein;; Retroviral aspartyl protease	Retrotransposon-derived protein PEG10 GN=PEG10 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: retrotransposon-derived protein PEG10 [Galeopterus variegatus]
ENSG00000242372(EIF6)	--	113.21257	2572	110.66396	2545	129.16021	2868	156.247906	3527	139.958555	3101	102.394074	2293	0.722772989	0.424501345	normal	0.959841439	0.263499272	normal	0.908332252	-0.330904544	normal	0.686778393	0.137702171	normal	[J]	"Translation, ribosomal structure and biogenesis"	Biological Process: mature ribosome assembly (GO:0042256);; Molecular Function: ribosome binding (GO:0043022);; 	"K03264|1.20753e-179|ptr:458200|EIF6, ITGB4BP; eukaryotic translation initiation factor 6; K03264 translation initiation factor 6 (A)"	Ribosome biogenesis in eukaryotes (ko03008)	[J]	"Translation, ribosomal structure and biogenesis"	eIF-6 family	Eukaryotic translation initiation factor 6 {ECO:0000255|HAMAP-Rule:MF_03132} GN=OK/SW-cl.27 OS=Homo sapiens (Human) PE=1 SV=1	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 6 isoform 1 [Ceratotherium simum simum]
ENSG00000242485(MRPL20)	--	61.776897	597	64.11258	639	56.90704	577	79.98199008	815	71.49881	705	72.7307	723	0.665948289	0.417314479	normal	0.967601748	0.120110072	normal	0.875909513	0.316390603	normal	0.14533625	0.285311488	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: intracellular (GO:0005622);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; Molecular Function: rRNA binding (GO:0019843);; 	"K02887|6.73036e-61|ptr:747422|39S ribosomal protein L20, mitochondrial; K02887 large subunit ribosomal protein L20 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L20	"39S ribosomal protein L20, mitochondrial (Precursor) GN=MRPL20 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"Chain L, Structural Model For The Large Subunit Of The Mammalian Mitochondrial Ribosome"
ENSG00000242612(DECR2)	--	18.245678	477	17.38274824	471	15.7200612	385	13.80160172	374	18.33954248	459	16.81943601	439	0.783017261	-0.380395546	normal	0.968770067	-0.058469284	normal	0.951949025	0.180406993	normal	0.781587836	-0.088588314	normal	[IQR]	"Lipid transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	--	"K13237|0|hsa:26063|DECR2, PDCR, SDR17C1; 2,4-dienoyl CoA reductase 2, peroxisomal (EC:1.3.1.34); K13237 peroxisomal 2,4-dienoyl-CoA reductase [EC:1.3.1.34] (A)"	Peroxisome (ko04146)	[R]	General function prediction only	Enoyl-(Acyl carrier protein) reductase;; short chain dehydrogenase;; KR domain	"Peroxisomal 2,4-dienoyl-CoA reductase GN=DECR2 OS=Homo sapiens (Human) PE=1 SV=1"	Q	"Secondary metabolites biosynthesis, transport and catabolism"	"PREDICTED: peroxisomal 2,4-dienoyl-CoA reductase [Physeter catodon]"
ENSG00000242689(CNTF)	--	0.506992	48	0.4754398	47	0.511521	42	0.562536	54	1.080893	83	0.756688	46	0.976989903	0.135016771	normal	0.551546381	0.779910006	normal	0.97913786	0.118862402	normal	0.508496215	0.396140777	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; Biological Process: growth (GO:0040007);; 	"K05420|7.78677e-148|hsa:1270|CNTF, HCNTF; ciliary neurotrophic factor; K05420 ciliary neurotrophic factor (A)"	Cytokine-cytokine receptor interaction (ko04060);; Jak-STAT signaling pathway (ko04630)	--	--	Ciliary neurotrophic factor	Ciliary neurotrophic factor GN=CNTF OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ciliary neurotrophic factor [Galeopterus variegatus]
ENSG00000242732(RGAG4)	--	0.933505	85	0.810012	74	0.63359	58	0.263301	24	0.151137	13	0.666382	61	2.84E-05	-1.790380074	down	2.53E-07	-2.399532304	down	0.976170339	0.062866421	normal	0.057803202	-1.165517627	normal	--	--	--	--	--	--	--	Retrotransposon gag protein	Retrotransposon gag domain-containing protein 4 GN=RGAG4 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: retrotransposon gag domain-containing protein 4 [Ceratotherium simum simum]
ENSG00000242802(AP5Z1)	--	9.096173624	572	10.81887554	695	8.890195185	572	10.275262	636	11.31618922	722	15.704684	1021	0.966560743	0.121868829	normal	0.974511153	0.033487809	normal	0.000313663	0.825947499	normal	0.388276341	0.351443497	normal	--	--	Cellular Component: AP-5 adaptor complex (GO:0044599);; 	--	--	--	--	"AP-5 complex subunit, vesicle trafficking"	AP-5 complex subunit zeta-1 GN=AP5Z1 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: AP-5 complex subunit zeta-1-like isoform X1 [Galeopterus variegatus]
ENSG00000242866(STRC)	--	0.0810331	4	0.00896991	1	0.0264109	0	0.0274855	2	0.024265174	1	0.048540157	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Stereocilin (Precursor) GN=STRC OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: stereocilin [Tupaia chinensis]
ENSG00000242950(ERVW-1)	--	0.145482188	7	0.2552999	13	0.037280982	1	0.111626117	6	0.2703793	13	0.154833	8	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	ENV polyprotein (coat polyprotein)	Transmembrane protein (Precursor) GN=ERVW-1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: ERV-W1 provirus ancestral Env polyprotein-like [Canis lupus familiaris]
ENSG00000243073(PRAMEF4)	--	0	0	0	0	0	0	0	0	0	0	0.032072	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Leucine Rich repeats (2 copies)	PRAME family member 4 GN=PRAMEF4 OS=Homo sapiens (Human) PE=2 SV=4	R	General function prediction only	PREDICTED: PRAME family member 12-like [Galeopterus variegatus]
ENSG00000243137(PSG4)	--	0.341400506	6	0.205708481	4	0.228084482	4	0.74301327	25	1.067071151	15	0.431983634	10	0.391896013	1.789220534	normal	--	--	--	--	--	--	--	--	--	--	--	--	K06500|0|pps:103785307|pregnancy-specific beta-1-glycoprotein 4; K06500 pregnancy specific beta-1-glycoprotein (A)	--	--	--	Immunoglobulin domain;; Immunoglobulin V-set domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin domain;; Alphaherpesvirus glycoprotein E	Pregnancy-specific beta-1-glycoprotein 4 (Precursor) GN=PSG4 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: carcinoembryonic antigen-related cell adhesion molecule 1-like [Panthera tigris altaica]
ENSG00000243147(MRPL33)	--	231.4352	939	228.1789	923	242.9476	997	223.7933	953	195.6061	781	224.3814	957	0.978870369	-0.009465833	normal	0.92846295	-0.261967417	normal	0.977608193	-0.067261877	normal	0.645570781	-0.108508249	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	K02913|3.51168e-39|ptr:100613895|MRPL33; mitochondrial ribosomal protein L33; K02913 large subunit ribosomal protein L33 (A)	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L33	"39S ribosomal protein L33, mitochondrial GN=MRPL33 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L33, mitochondrial [Myotis davidii]"
ENSG00000243156(MICAL3)	--	9.539803394	1915	8.710036078	1776	10.72185055	2196	11.91380749	2370	11.06494073	2265	10.45384478	2040	0.944904789	0.276510684	normal	0.901446161	0.329204154	normal	0.983699844	-0.114518499	normal	0.410743295	0.15994537	normal	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; Molecular Function: FAD binding (GO:0071949);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Protein of unknown function (DUF3585);; Calponin homology (CH) domain;; CAMSAP CH domain;; LIM domain;; FAD binding domain	Protein-methionine sulfoxide oxidase MICAL3 GN=MICAL3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: protein-methionine sulfoxide oxidase MICAL3 isoform X16 [Oryctolagus cuniculus]
ENSG00000243317(C7orf73)	--	23.003523	674	22.347419	671	22.41568	650	29.611498	875	27.078631	791	23.543284	712	0.837770239	0.345010276	normal	0.9474232	0.215490651	normal	0.968072265	0.122872854	normal	0.251623074	0.231485767	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C7orf73 (Precursor) OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: uncharacterized protein LOC102467981 [Tupaia chinensis]
ENSG00000243335(KCTD7)	--	9.113635	561	8.7815247	650	8.165740695	525	6.65310555	472	6.211210692	375	8.586797	596	0.908601694	-0.279211225	normal	0.001334208	-0.812454097	normal	0.956364499	0.174232139	normal	0.362871703	-0.28753838	normal	--	--	Biological Process: protein homooligomerization (GO:0051260);; 	--	--	[R]	General function prediction only	BTB/POZ domain	BTB/POZ domain-containing protein KCTD7 GN=KCTD7 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: rab5 GDP/GTP exchange factor isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000243440(AF165138.7)	--	0	0	0	0	0	0	0	0	0	0	0.087558662	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative uncharacterized protein ENSP00000383407 OS=Homo sapiens (Human) PE=5 SV=1	S	Function unknown	PREDICTED: SAM domain-containing protein SAMSN-1 [Oryctolagus cuniculus]
ENSG00000243449(C4orf48)	--	122.72818	317	136.64711	376	148.16308	418	179.10425	517	182.22405	468	160.89468	437	0.036980285	0.672274658	normal	0.89838233	0.293290175	normal	0.968971448	0.055642001	normal	0.133833063	0.334664948	normal	--	--	--	--	--	--	--	Neuropeptide-like	Neuropeptide-like protein C4orf48 (Precursor) GN=C4orf48 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: neuropeptide-like protein C4orf48 homolog [Lipotes vexillifer]
ENSG00000243509(TNFRSF6B)	--	1.45702	25	1.07956	19	0.659524	11	0.74937	13	0.956411	16	0.457992	8	0.942273913	-0.896609996	normal	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K05143|2.57491e-163|hsa:8771|TNFRSF6B, DCR3, DJ583P15.1.1, M68, M68E, TR6; tumor necrosis factor receptor superfamily, member 6b, decoy; K05143 tumor necrosis factor receptor superfamily member 6B (A)"	Cytokine-cytokine receptor interaction (ko04060)	--	--	TNFR/NGFR cysteine-rich region	Tumor necrosis factor receptor superfamily member 6B (Precursor) GN=TNFRSF6B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: tumor necrosis factor receptor superfamily member 6B [Ceratotherium simum simum]
ENSG00000243566(UPK3B)	--	9.572252	272	14.18399869	354	8.194617	270	6.313561	220	7.953557	249	13.13767	429	0.878271221	-0.334827725	normal	0.428940193	-0.526334365	normal	0.066056811	0.656783135	normal	0.986272296	-0.016276607	normal	--	--	--	--	--	--	--	--	Uroplakin-3b (Precursor) GN=UPK3B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: uroplakin-3b isoform X3 [Bubalus bubalis]
ENSG00000243660(ZNF487)	--	1.837659584	54	0.943254936	43	0.794447283	35	1.56071758	36	0.753019445	36	0.399520086	20	0.912599453	-0.59491722	normal	0.974351827	-0.267471096	normal	0.922069385	-0.771049398	normal	0.392251378	-0.543978357	normal	--	--	--	--	--	[R]	General function prediction only	--	Putative zinc finger protein 487 GN=ZNF487 OS=Homo sapiens (Human) PE=5 SV=3	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: putative zinc finger protein 487 [Orycteropus afer afer]
ENSG00000243667(WDR92)	--	9.53527	420	11.93118593	493	11.5268211	479	8.92146352	397	7.852277	341	8.526325	330	0.963864456	-0.111662344	normal	0.267008027	-0.551197115	normal	0.283698619	-0.54377046	normal	0.059892495	-0.403985012	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	WD repeat-containing protein 92 GN=WDR92 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: WD repeat-containing protein 92 [Camelus bactrianus]
ENSG00000243710(CFAP57)	--	0.386210088	38	0.297816927	27	0.675823691	28	0.113958783	12	0.111007876	11	0.221497066	20	0.132225196	-1.574816157	normal	0.801343047	-1.207802025	normal	0.977076875	-0.463942367	normal	0.070464581	-1.132732938	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	"WD domain, G-beta repeat"	Cilia- and flagella-associated protein 57 {ECO:0000312|HGNC:HGNC:26485} OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: WD repeat-containing protein 65 [Canis lupus familiaris]
ENSG00000243716(NPIPB5)	--	14.44308067	254	20.58300929	291	17.48376879	265	15.65982684	250	12.62362183	263	25.0046722	406	0.966000525	-0.053407025	normal	0.95272391	-0.166472407	normal	0.158870235	0.604388976	normal	0.75045786	0.162329604	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B5 GN=NPIPB5 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000243725(TTC4)	--	9.7929094	446	11.526008	529	9.048339716	411	13.10023	596	11.71375877	526	10.11984617	460	0.760934293	0.386281808	normal	0.971236642	-0.029546773	normal	0.958188336	0.153669306	normal	0.508894623	0.168513645	normal	[R]	General function prediction only	--	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	TPR repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Tetratricopeptide repeat protein 4 GN=TTC4 OS=Homo sapiens (Human) PE=1 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: tetratricopeptide repeat protein 4 isoform X1 [Sus scrofa]
ENSG00000243749(TMEM35B)	--	19.403213	246	19.047886	248	17.249911	224	19.430728	248	15.656404	203	18.53225	251	0.966979587	-0.019032073	normal	0.901758288	-0.308205743	normal	0.956214985	0.154908736	normal	0.905683714	-0.053930838	normal	--	--	--	--	--	--	--	DoxX-like family;; DoxX	Uncharacterized protein ZMYM6NB (Precursor) GN=ZMYM6NB OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein ZMYM6NB [Orcinus orca]
ENSG00000243811(APOBEC3D)	--	28.13133565	1403	29.22669726	1462	30.26395519	1500	22.28920956	1116	20.88494651	1029	25.92640306	1300	0.824698738	-0.360566375	normal	0.247938428	-0.527472916	normal	0.960698933	-0.214509798	normal	0.022881345	-0.362175771	normal	--	--	"Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines (GO:0016814);; "	"K18750|0|hsa:140564|APOBEC3D, A3D, APOBEC3DE, APOBEC3E, ARP6; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D; K18750 C->U-editing enzyme APOBEC3 [EC:3.5.4.-] (A)"	--	--	--	APOBEC-like N-terminal domain;; APOBEC-like C-terminal domain;; Cytidine and deoxycytidylate deaminase zinc-binding region	DNA dC-	L	"Replication, recombination and repair"	PREDICTED: DNA dC-
ENSG00000243910(TUBA4B)	--	0	0	0.120228	3	0	0	0	0	0.0392744	0	0.0797058	2	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	K07374|7.42312e-108|bom:102270390|tubulin alpha-1A chain-like; K07374 tubulin alpha (A)	Phagosome (ko04145);; Gap junction (ko04540)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain"	Putative tubulin-like protein alpha-4B GN=TUBA4B OS=Homo sapiens (Human) PE=5 SV=2	Z	Cytoskeleton	PREDICTED: tubulin alpha-1C chain [Leptonychotes weddellii]
ENSG00000243943(ZNF512)	--	18.1734192	1171	18.29344302	1191	20.25148608	1297	11.16859568	726	9.629859019	620	12.89650321	832	0.004172292	-0.719320822	normal	5.64E-06	-0.961536214	normal	0.02218446	-0.647863385	normal	1.41E-07	-0.769126172	normal	--	--	--	--	--	[R]	General function prediction only	"C2H2-type zinc finger;; CpXC protein;; Zinc-finger double-stranded RNA-binding;; Zinc finger, C2H2 type"	Zinc finger protein 512 GN=ZNF512 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 512 [Galeopterus variegatus]
ENSG00000243955(GSTA1)	--	0	0	0	0	0	0	0.0584713	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K00799|4.77879e-150|hsa:2938|GSTA1, GST2, GSTA1-1, GTH1; glutathione S-transferase alpha 1 (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	"Glutathione S-transferase A1, N-terminally processed GN=GSTA1 OS=Homo sapiens (Human) PE=1 SV=3"	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase A1 [Chrysochloris asiatica]
ENSG00000243978(RGAG1)	--	0	0	0	0	0	0	0	0	0.008286068	0	0.0253845	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Retrotransposon gag protein	Retrotransposon gag domain-containing protein 1 GN=RGAG1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: retrotransposon gag domain-containing protein 1 [Ceratotherium simum simum]
ENSG00000244005(NFS1)	--	21.78879084	809	20.10714861	703	23.02503896	864	22.15550454	821	23.82725914	828	26.44650169	939	0.977125111	-0.0095717	normal	0.948669358	0.214254452	normal	0.973115176	0.111614958	normal	0.680217469	0.102778265	normal	[E]	Amino acid transport and metabolism	Biological Process: cellular amino acid metabolic process (GO:0006520);; Molecular Function: lyase activity (GO:0016829);; 	K04487|0|pps:100988455|NFS1; NFS1 cysteine desulfurase; K04487 cysteine desulfurase [EC:2.8.1.7] (A)	Thiamine metabolism (ko00730);; Sulfur relay system (ko04122)	[E]	Amino acid transport and metabolism	Aminotransferase class-V;; Beta-eliminating lyase;; DegT/DnrJ/EryC1/StrS aminotransferase family	"Cysteine desulfurase, mitochondrial (Precursor) GN=NFS1 OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: cysteine desulfurase, mitochondrial isoform X1 [Eptesicus fuscus]"
ENSG00000244038(DDOST)	--	134.03289	4325	128.2897274	4211	126.2807832	4086	140.1597788	4567	137.508712	4415	134.9741585	4384	0.992446922	0.047697904	normal	0.992026407	0.046807587	normal	0.991017449	0.093233833	normal	0.811018345	0.061238688	normal	--	--	Cellular Component: endoplasmic reticulum membrane (GO:0005789);; Biological Process: protein N-linked glycosylation via asparagine (GO:0018279);; 	K12670|0|pps:100971894|DDOST; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic); K12670 oligosaccharyltransferase complex subunit beta (A)	N-Glycan biosynthesis (ko00510);; Protein processing in endoplasmic reticulum (ko04141)	[O]	"Posttranslational modification, protein turnover, chaperones"	Oligosaccharyltransferase 48 kDa subunit beta	Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit (Precursor) GN=DDOST OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: LOW QUALITY PROTEIN: dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit [Myotis lucifugus]
ENSG00000244045(TMEM199)	--	8.169453937	422	9.14620296	485	11.44476687	589	8.5353478	446	8.597309042	448	9.55351716	526	0.969317836	0.048795633	normal	0.961112329	-0.135472904	normal	0.957056242	-0.17103132	normal	0.766535525	-0.095467584	normal	--	--	--	--	--	--	--	Endoplasmic reticulum-based factor for assembly of V-ATPase	Transmembrane protein 199 GN=TMEM199 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 199 [Ceratotherium simum simum]
ENSG00000244067(GSTA2)	--	0	0	0	0	0	0	0.0922138	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	"K00799|8.16606e-150|hsa:2939|GSTA2, GST2, GSTA2-2, GTA2, GTH2; glutathione S-transferase alpha 2 (EC:2.5.1.18); K00799 glutathione S-transferase [EC:2.5.1.18] (A)"	Glutathione metabolism (ko00480);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Chemical carcinogenesis (ko05204)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain"	Glutathione S-transferase A2 GN=GSTA2 OS=Homo sapiens (Human) PE=1 SV=4	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: glutathione S-transferase A1 [Chrysochloris asiatica]
ENSG00000244187(TMEM141)	--	34.6216	410	26.499	318	32.0836	388	36.1826	438	34.7665	410	32.4631	390	0.968304778	0.064241766	normal	0.850851047	0.343727612	normal	0.969572015	-0.000870586	normal	0.672005524	0.128296817	normal	--	--	--	--	--	--	--	TMEM141 protein family	Transmembrane protein 141 GN=TMEM141 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: transmembrane protein 141 [Odobenus rosmarus divergens]
ENSG00000244219(GS1-259H13.2)	--	2.341123015	30	0.844379947	11	2.327003133	30	0.523445705	7	0.903137	12	1.223832663	16	0.098778592	-1.912617485	normal	--	--	--	0.924415566	-0.855281412	normal	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC100687089 isoform X2 [Canis lupus familiaris]
ENSG00000244274(DBNDD2)	--	8.324344289	160	6.156733043	117	8.210124135	167	9.886611782	187	9.577241873	182	6.859280593	132	0.952187702	0.192423686	normal	0.450232189	0.609638443	normal	0.903463094	-0.344088546	normal	0.73341311	0.152532455	normal	--	--	Cellular Component: cytoplasm (GO:0005737);; 	--	--	--	--	Dysbindin (Dystrobrevin binding protein 1)	Dysbindin domain-containing protein 2 GN=DBNDD2 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: dysbindin domain-containing protein 2 [Orcinus orca]
ENSG00000244405(ETV5)	--	17.55719186	1255	17.62775873	1249	17.35367668	1226	14.0431034	998	15.52409265	1102	15.82556022	1110	0.819150325	-0.360911146	normal	0.960799178	-0.20181546	normal	0.971641387	-0.151494263	normal	0.187832389	-0.237481195	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K15593|0|nle:100592153|ETV5; ets variant 5; K15593 ets translocation variant 5 (A)	Transcriptional misregulation in cancer (ko05202)	[K]	Transcription	PEA3 subfamily ETS-domain transcription factor N terminal domain;; Ets-domain	ETS translocation variant 5 GN=ETV5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: ETS translocation variant 5 isoform 1 [Odobenus rosmarus divergens] 
ENSG00000244476(ERVFRD-1)	--	0	0	0.05415711	3	0.05336149	2	0.01776411	1	0.034321464	1	0.05254371	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	ENV polyprotein (coat polyprotein)	Transmembrane protein (Precursor) GN=ERVFRD-1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"ERV-FRD provirus ancestral Env polyprotein, partial [Bos mutus]"
ENSG00000244482(LILRA6)	--	0	0	0	0	0	0	0	0	0.0509212	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06512|0|hsa:79168|LILRA6, CD85b, ILT-8, ILT5, ILT8, LILRB3, LILRB6; leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6; K06512 leukocyte immunoglobulin-like receptor (A)"	Osteoclast differentiation (ko04380)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Leukocyte immunoglobulin-like receptor subfamily A member 6 (Precursor) GN=LILRA6 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: leukocyte immunoglobulin-like receptor subfamily B member 1 [Camelus dromedarius]
ENSG00000244486(SCARF2)	--	1.3362344	59	1.090642463	52	0.984531467	45	0.631180485	31	1.19397019	55	0.248304928	11	0.553321743	-0.925459771	normal	0.976467575	0.057857272	normal	0.006016585	-1.901921896	down	0.317811595	-0.708374327	normal	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin EGF-like (Domains III and V)	Scavenger receptor class F member 2 (Precursor) GN=SCARF2 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: scavenger receptor class F member 2 isoform 2 [Odobenus rosmarus divergens]
ENSG00000244607(CCDC13)	--	0.0136047	1	0	0	0.0130191	0	0	0	0.0264556	1	0.0269467	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 13 GN=CCDC13 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 13 [Equus caballus]
ENSG00000244617(ASPRV1)	--	0.203976	8	0.320901	13	0.171577	6	0.177017	7	0.124878	4	0.0253281	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Biological Process: proteolysis (GO:0006508);; 	--	--	--	--	Aspartyl protease;; Aspartyl protease;; Retroviral aspartyl protease	Retroviral-like aspartic protease 1 (Precursor) OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: retroviral-like aspartic protease 1 [Galeopterus variegatus]
ENSG00000244694(PTCHD4)	--	0.1698635	9	0.1327878	7	0.1694439	8	0.1686864	9	0.118442071	5	0.261955	14	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[R]	General function prediction only	Patched family;; Sterol-sensing domain of SREBP cleavage-activation	Patched domain-containing protein 4 GN=PTCHD4 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: patched domain-containing protein 4 isoform X1 [Oryctolagus cuniculus]
ENSG00000244731(C4A)	--	0.045179863	5	0.098068682	11	0.052532025	5	0.027114357	3	0.043935639	4	0.116584526	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: endopeptidase inhibitor activity (GO:0004866);; Cellular Component: extracellular region (GO:0005576);; Cellular Component: extracellular space (GO:0005615);; 	"K03989|0|hsa:721|C4B, C4B1, C4B12, C4B2, C4B3, C4B5, C4BD, C4B_2, C4F, CH, CO4, CPAMD3; complement component 4B (Chido blood group); K03989 complement component 4 (A)"	Complement and coagulation cascades (ko04610);; Pertussis (ko05133);; Staphylococcus aureus infection (ko05150);; Systemic lupus erythematosus (ko05322)	[O]	"Posttranslational modification, protein turnover, chaperones"	A-macroglobulin complement component;; A-macroglobulin receptor;; Alpha-2-macroglobulin family;; Alpha-2-macroglobulin family N-terminal region;; UNC-6/NTR/C345C module;; MG2 domain;; Alpha-macro-globulin thiol-ester bond-forming region;; Anaphylotoxin-like domain;; Prenyltransferase-like;; Prenyltransferase-like	Complement C4 gamma chain (Precursor) GN=C4A OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: complement C4-A isoform X1 [Galeopterus variegatus]
ENSG00000244752(CRYBB2)	--	0	0	0.0708913	1	0.138156	1	0.210513	3	0.13915	1	0.140089	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Beta/Gamma crystallin;; Beta/Gamma crystallin	Beta-crystallin B2 GN=CRYBB2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: beta-crystallin B2 [Tupaia chinensis]
ENSG00000244754(N4BP2L2)	--	11.46913275	770	14.62738372	1004	12.73487876	832	10.53019115	740	9.629883961	700	12.548543	922	0.972921443	-0.087986327	normal	0.214068249	-0.540777782	normal	0.969180555	0.139650558	normal	0.590310728	-0.162559155	normal	--	--	--	--	--	--	--	--	NEDD4-binding protein 2-like 2 GN=N4BP2L2 OS=Homo sapiens (Human) PE=1 SV=1	L	"Replication, recombination and repair"	PREDICTED: NEDD4-binding protein 2-like 2 [Galeopterus variegatus]
ENSG00000245848(CEBPA)	--	9.19574	390	7.33324	320	7.29984	323	4.30088	184	3.72443	158	4.9437	212	4.51E-06	-1.108087969	down	0.000108961	-1.032480904	down	0.195706004	-0.612196764	normal	2.29E-05	-0.919835138	normal	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09055|5.36577e-123|pale:102893139|CEBPA; CCAAT/enhancer binding protein (C/EBP), alpha; K09055 CCAAT/enhancer binding protein (C/EBP), alpha (A)"	Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Pathways in cancer (ko05200);; Transcriptional misregulation in cancer (ko05202);; Acute myeloid leukemia (ko05221)	[K]	Transcription	Basic region leucine zipper;; bZIP transcription factor	CCAAT/enhancer-binding protein alpha GN=CEBPA OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: CCAAT/enhancer-binding protein alpha [Dasypus novemcinctus]
ENSG00000246705(H2AFJ)	--	158.977	1267	123.382	1025	139.014	1168	154.097	1289	168.864	1350	162.186	1322	0.982314987	-0.005989324	normal	0.798919262	0.375424943	normal	0.969409204	0.170183225	normal	0.376138392	0.174079414	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|9.71199e-78|umr:103677774|histone H2A.J; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A.J GN=H2AFJ OS=Homo sapiens (Human) PE=1 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone H2A.J-like [Odobenus rosmarus divergens]
ENSG00000246922(UBAP1L)	--	0.592909096	66	1.062695334	100	0.777402711	73	0.409071738	58	0.733673338	74	0.307090832	48	0.9698141	-0.211976793	normal	0.890514138	-0.447923443	normal	0.853253656	-0.597772418	normal	0.39790268	-0.430847557	normal	--	--	--	--	--	--	--	--	Ubiquitin-associated protein 1-like GN=UBAP1L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: ubiquitin-associated protein 1-like [Ceratotherium simum simum]
ENSG00000247315(ZCCHC3)	--	14.159	806	14.5241	848	13.1451	771	12.3902	716	13.0857	745	14.0169	805	0.953076308	-0.201245176	normal	0.951586188	-0.207854591	normal	0.975667741	0.05386308	normal	0.623059952	-0.118806562	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: zinc ion binding (GO:0008270);; 	--	--	--	--	Zinc knuckle	Zinc finger CCHC domain-containing protein 3 GN=ZCCHC3 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: zinc finger CCHC domain-containing protein 3 isoform X1 [Lipotes vexillifer]
ENSG00000247595(SPTY2D1-AS1)	--	1.000080129	1	0	0	2.737340148	2	0	0	1.465110343	2	0.174403	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	hypothetical protein PANDA_015817 [Ailuropoda melanoleuca]
ENSG00000247626(MARS2)	--	7.15354	307	7.90253	343	9.4567	408	7.14725	309	5.50065	236	5.46075	235	0.967740405	-0.021357542	normal	0.336654775	-0.557864602	normal	0.004991775	-0.800241225	normal	0.049446839	-0.46151722	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: nucleotide binding (GO:0000166);; Molecular Function: aminoacyl-tRNA ligase activity (GO:0004812);; Molecular Function: ATP binding (GO:0005524);; Biological Process: tRNA aminoacylation for protein translation (GO:0006418);; 	"K01874|0|hsa:92935|MARS2, MetRS, mtMetRS; methionyl-tRNA synthetase 2, mitochondrial (EC:6.1.1.10); K01874 methionyl-tRNA synthetase [EC:6.1.1.10] (A)"	Selenocompound metabolism (ko00450);; Aminoacyl-tRNA biosynthesis (ko00970)	[J]	"Translation, ribosomal structure and biogenesis"	"tRNA synthetases class I (M);; tRNA synthetases class I (I, L, M and V);; tRNA synthetases class I (C) catalytic domain"	"Methionine--tRNA ligase, mitochondrial (Precursor) GN=MARS2 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: methionine--tRNA ligase, mitochondrial [Ceratotherium simum simum]"
ENSG00000247746(USP51)	--	1.278447061	102	1.322920863	104	0.995802341	80	0.697002001	56	0.856947667	50	1.079673467	81	0.196192627	-0.877782184	normal	0.033280041	-1.05538099	normal	0.973087317	0.009452879	normal	0.137988571	-0.633520179	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	K11366|0|hsa:158880|USP51; ubiquitin specific peptidase 51 (EC:3.4.19.12); K11366 ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12] (A)	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase;; Zn-finger in ubiquitin-hydrolases and other protein	Ubiquitin carboxyl-terminal hydrolase 51 GN=USP51 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 51-like [Vicugna pacos]
ENSG00000248109(CTC-295J13.3)	--	0	0	0	0	0.118583868	2	0.039510591	1	0.038971223	0	0.118861689	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Collagen triple helix repeat (20 copies)	--	R	General function prediction only	PREDICTED: collagen alpha-1(III) chain-like [Camelus ferus]
ENSG00000248329(APELA)	--	0.0267943	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Apelin receptor early endogenous ligand (Precursor) GN=APELA OS=Homo sapiens (Human) PE=2 SV=1	--	--	PREDICTED: apelin receptor early endogenous ligand-like [Galeopterus variegatus]
ENSG00000248333(CDK11B)	--	9.330957266	723	9.720090472	780	10.025578	806	9.814647329	770	9.062496346	699	10.19603358	792	0.974625193	0.059907169	normal	0.958454115	-0.179240899	normal	0.976566785	-0.033507427	normal	0.862752451	-0.051345525	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08818|0|mcf:102123466|CDK11B; cyclin-dependent kinase 11B; K08818 cell division cycle 2-like [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 11B GN=CDK11B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: cyclin-dependent kinase 11B-like isoform X2 [Tupaia chinensis]
ENSG00000248483(POU5F2)	--	0.0251656	3	0.0168673	2	0.00843029	0	0.0250306	3	0.00811124	0	0.00830957	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: DNA binding (GO:0003677);; Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Pou domain - N-terminal to homeobox domain;; Homeobox domain	"POU domain, class 5, transcription factor 2 GN=POU5F2 OS=Homo sapiens (Human) PE=2 SV=1"	K	Transcription	"PREDICTED: LOW QUALITY PROTEIN: POU domain class 5, transcription factor 2 [Equus caballus]"
ENSG00000248712(CCDC153)	--	0.260203056	8	0.21325347	5	0.131850543	2	0	0	0.042251538	0	0.214632001	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 153 GN=CCDC153 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: coiled-coil domain-containing protein 153 [Equus caballus]
ENSG00000248713(RP11-766F14.2)	--	0.00497365	1	0	0	0	0	0.00499326	1	0	0	0.00492455	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4585)	Proline-rich basic protein 1 GN=PROB1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein LOC102902241 [Felis catus]
ENSG00000248746(ACTN3)	--	0.014859733	1	0	0	0.014156789	0	0	0	0.014445101	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: protein binding (GO:0005515);; 	"K05699|0|hsa:89|ACTN3; actinin, alpha 3 (gene/pseudogene); K05699 actinin alpha (A)"	Focal adhesion (ko04510);; Adherens junction (ko04520);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Regulation of actin cytoskeleton (ko04810);; Amoebiasis (ko05146);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412)	[Z]	Cytoskeleton	Spectrin repeat;; Calponin homology (CH) domain;; Ca2+ insensitive EF hand;; CAMSAP CH domain;; EF hand	Alpha-actinin-3 GN=ACTN3 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: alpha-actinin-3 [Camelus dromedarius]
ENSG00000248771(LINC01207)	--	0.0189274	1	0.0566317	3	0	0	0.0751025	4	0.0549945	2	0.206262	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000248905(FMN1)	--	0.940068336	224	1.08805323	226	0.603297588	145	1.2842176	195	1.436876752	312	1.495042626	254	0.94057801	-0.229170413	normal	0.708881724	0.441273849	normal	0.025342378	0.79414689	normal	0.466278509	0.33398051	normal	--	--	--	K10367|0|pps:100970236|FMN1; formin 1; K10367 formin 1 (A)	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Formin Homology 2 Domain	Formin-1 GN=FMN1 OS=Homo sapiens (Human) PE=2 SV=3	TZ	Signal transduction mechanisms;; Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: formin-1 [Equus przewalskii]
ENSG00000249115(HAUS5)	--	8.330326025	586	8.79403898	569	9.684355522	683	9.954770013	655	8.812966966	588	9.524716907	643	0.965849594	0.129440872	normal	0.972341788	0.025893248	normal	0.970802554	-0.095141131	normal	0.968742065	0.016215746	normal	--	--	Biological Process: spindle assembly (GO:0051225);; Cellular Component: HAUS complex (GO:0070652);; 	"K16588|0|hsa:23354|HAUS5, KIAA0841, dgt5; HAUS augmin-like complex, subunit 5; K16588 HAUS augmin-like complex subunit 5 (A)"	--	--	--	HAUS augmin-like complex subunit 5	HAUS augmin-like complex subunit 5 GN=HAUS5 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: HAUS augmin-like complex subunit 5 isoform X1 [Tupaia chinensis]
ENSG00000249222(ATP5L2)	--	0	0	0.0923945	1	0	0	0	0	0	0	0.0912579	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) (GO:0000276);; Molecular Function: hydrogen ion transmembrane transporter activity (GO:0015078);; Biological Process: ATP synthesis coupled proton transport (GO:0015986);; "	--	--	[C]	Energy production and conversion	Mitochondrial ATP synthase g subunit	"ATP synthase subunit g 2, mitochondrial GN=ATP5L2 OS=Homo sapiens (Human) PE=5 SV=1"	F	Nucleotide transport and metabolism	"PREDICTED: ATP synthase subunit g, mitochondrial [Tupaia chinensis] "
ENSG00000249242(TMEM150C)	--	1.451952	83	1.124136262	52	2.464455797	74	1.556693002	91	1.684427195	102	0.948257489	52	0.970505591	0.100152064	normal	0.134371985	0.930892632	normal	0.90492946	-0.504932469	normal	0.75598694	0.207080773	normal	--	--	--	--	--	--	--	Frag1/DRAM/Sfk1 family	Transmembrane protein 150C GN=TMEM150C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 150C isoform X3 [Tupaia chinensis] 
ENSG00000249437(NAIP)	--	1.394487	127	1.652260917	157	1.41454	129	1.837290243	175	1.951679201	168	2.162101	205	0.832412721	0.427274651	normal	0.964294918	0.075566401	normal	0.266263109	0.653828935	normal	0.257269258	0.387076637	normal	--	--	--	"K12807|0|hsa:4671|NAIP, BIRC1, NLRB1, psiNAIP; NLR family, apoptosis inhibitory protein; K12807 baculoviral IAP repeat-containing protein 1 (A)"	NOD-like receptor signaling pathway (ko04621);; Legionellosis (ko05134)	--	--	Inhibitor of Apoptosis domain;; NACHT domain	Baculoviral IAP repeat-containing protein 1 GN=NAIP OS=Homo sapiens (Human) PE=1 SV=3	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: baculoviral IAP repeat-containing protein 1 isoform X3 [Galeopterus variegatus]
ENSG00000249459(ZNF286B)	--	3.805456157	92	3.95005078	93	2.953259813	72	4.31089544	98	3.838340898	95	2.333641747	61	0.970810679	0.059355154	normal	0.970153336	0.009123455	normal	0.965347669	-0.241951481	normal	0.967635723	-0.039799782	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain"	Putative zinc finger protein 286B GN=ZNF286B OS=Homo sapiens (Human) PE=5 SV=1	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 286A [Equus caballus]
ENSG00000249471(ZNF324B)	--	3.634849997	198	3.469630793	211	4.337368001	253	4.749905282	237	4.396259734	249	4.627643051	276	0.940720311	0.226943126	normal	0.941884925	0.216049458	normal	0.961330121	0.116572125	normal	0.599377817	0.182610621	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:388569|ZNF324B; zinc finger protein 324B; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 324B GN=ZNF324B OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 324A-like [Galeopterus variegatus]
ENSG00000249693(THEGL)	--	0.0350374	1	0.0356815	1	0	0	0.0349505	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testicular haploid expressed repeat	Testicular haploid expressed gene protein-like GN=THEGL OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testicular haploid expressed gene protein-like [Camelus dromedarius]
ENSG00000249715(FER1L5)	--	0	0	0	0	0	0	0	0	0	0	0.0136151	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[M]	Cell wall/membrane/envelope biogenesis	C2 domain;; FerB (NUC096) domain;; FerI (NUC094) domain;; Integral peroxisomal membrane peroxin;; FerA (NUC095) domain;; C2 domain	Fer-1-like protein 5 GN=FER1L5 OS=Homo sapiens (Human) PE=2 SV=2	M	Cell wall/membrane/envelope biogenesis	PREDICTED: LOW QUALITY PROTEIN: fer-1-like protein 5 [Ceratotherium simum simum]
ENSG00000249853(HS3ST5)	--	0.02376026	1	0	0	0.047351217	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K08104|0|hsa:222537|HS3ST5, 3-OST-5, 3OST5, HS3OST5, NBLA04021; heparan sulfate (glucosamine) 3-O-sulfotransferase 5 (EC:2.8.2.23); K08104 [heparan sulfate]-glucosamine 3-sulfotransferase 5 [EC:2.8.2.23] (A)"	Glycosaminoglycan biosynthesis - heparan sulfate / heparin (ko00534)	[O]	"Posttranslational modification, protein turnover, chaperones"	Sulfotransferase domain	Heparan sulfate glucosamine 3-O-sulfotransferase 5 GN=HS3ST5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heparan sulfate glucosamine 3-O-sulfotransferase 5 [Galeopterus variegatus]
ENSG00000249931(GOLGA8K)	--	0.407569	20	0.180671	9	0.236867	11	0.182212	9	0.0988541	4	0.100917	5	0.944539841	-1.058875335	normal	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8K OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000249961(TERB1)	--	0	0	0	0	0	0	0.222012724	4	0.180525121	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Myb-like DNA-binding domain	Telomere repeats-binding bouquet formation protein 1 GN=CCDC79 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 79 [Ceratotherium simum simum]
ENSG00000249992(TMEM158)	--	49.098	1024	30.3629	650	32.463	712	27.6116	581	14.7032	311	15.049	318	0.000163443	-0.846727017	normal	9.49E-07	-1.081229316	down	2.77E-08	-1.167329891	down	0.026787656	-1.003119056	normal	--	--	--	--	--	--	--	--	Transmembrane protein 158 (Precursor) GN=TMEM158 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 158 [Chrysochloris asiatica]
ENSG00000250091(DNAH10OS)	--	1.143034743	163	0.72182404	103	0.78766232	112	0.998603	141	1.373031164	195	1.11623006	160	0.944798818	-0.237598422	normal	0.016857679	0.889757847	normal	0.748477897	0.500598055	normal	0.32566688	0.371056023	normal	--	--	--	--	--	--	--	--	Uncharacterized protein DNAH10OS GN=DNAH10OS OS=Homo sapiens (Human) PE=2 SV=1	--	--	--
ENSG00000250305(KIAA1456)	--	0	0	0.033396361	2	0.038574556	5	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[QR]	"Secondary metabolites biosynthesis, transport and catabolism;; General function prediction only"	Cellular Component: nucleolus (GO:0005730);; Biological Process: metabolic process (GO:0008152);; Molecular Function: methyltransferase activity (GO:0008168);; 	--	--	[R]	General function prediction only	Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; Methyltransferase domain;; ubiE/COQ5 methyltransferase family;; Hypothetical methyltransferase	Probable tRNA methyltransferase 9-like protein GN=KIAA1456 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: putative methyltransferase KIAA1456 homolog [Galeopterus variegatus]
ENSG00000250312(ZNF718)	--	2.199083079	48	2.650525543	66	2.921630111	52	2.530053736	61	2.583098489	55	1.912710717	43	0.96497522	0.306231323	normal	0.962631242	-0.277485408	normal	0.97106989	-0.273699987	normal	0.926716713	-0.084580923	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:255403|ZNF718; zinc finger protein 718; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc ribbon domain;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C1-like domain;; Probable zinc-binding domain;; Ogr/Delta-like zinc finger"	Zinc finger protein 718 GN=ZNF718 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000250317(SMIM20)	--	17.27162278	215	13.88932099	174	14.59676774	188	13.21898714	168	14.5532516	182	19.26422681	244	0.849770165	-0.383597532	normal	0.96532551	0.043058664	normal	0.858317912	0.365271014	normal	0.975714352	0.021803377	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4538)	Small integral membrane protein 20 GN=SMIM20 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: small integral membrane protein 20-like [Galeopterus variegatus]
ENSG00000250423(KIAA1210)	--	0	0	0	0	0	0	0	0	0	0	0.00612768	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4592)	Uncharacterized protein KIAA1210 GN=KIAA1210 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein KIAA1210 homolog [Ceratotherium simum simum]
ENSG00000250479(CHCHD10)	--	141.2764	1261	117.2625	1144	149.0128	1245	135.968	1175	126.3523	1184	93.2319	802	0.974815804	-0.132572392	normal	0.980580105	0.028118933	normal	0.026013046	-0.641783722	normal	0.36129609	-0.229606955	normal	--	--	--	--	--	[S]	Function unknown	CHCH domain	"Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial (Precursor) GN=CHCHD10 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial, partial [Bubalus bubalis]"
ENSG00000250486(FAM218A)	--	0.634871	22	0.401797	14	0.543665	18	0.512239	18	0.362741	12	0.285414	10	0.986635531	-0.297341724	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM218A GN=FAM218A OS=Homo sapiens (Human) PE=2 SV=1	--	--	--
ENSG00000250506(CDK3)	--	14.13916206	296	16.39888617	382	13.89808453	276	12.17963634	245	12.52303564	306	18.661683	405	0.90036488	-0.301922011	normal	0.857225458	-0.339960369	normal	0.330408551	0.54249388	normal	0.983948554	-0.017070768	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K02088|0|hsa:1018|CDK3; cyclin-dependent kinase 3 (EC:2.7.11.22); K02088 cyclin-dependent kinase 3 [EC:2.7.11.22] (A)	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase	Cyclin-dependent kinase 3 GN=CDK3 OS=Homo sapiens (Human) PE=1 SV=1	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-dependent kinase 3 [Vicugna pacos]
ENSG00000250565(ATP6V1E2)	--	4.0635	146	3.39304	128	4.45076	160	1.683262	61	1.221601	43	1.528218	56	0.000200724	-1.268594814	down	7.71E-06	-1.561750906	down	1.94E-06	-1.497845399	down	8.04E-06	-1.460928199	down	[C]	Energy production and conversion	"Biological Process: ATP hydrolysis coupled proton transport (GO:0015991);; Biological Process: virion attachment to host cell (GO:0019062);; Cellular Component: proton-transporting two-sector ATPase complex, catalytic domain (GO:0033178);; Molecular Function: proton-transporting ATPase activity, rotational mechanism (GO:0046961);; "	"K02150|1.86997e-115|hsa:90423|ATP6V1E2, ATP6E1, ATP6EL2, ATP6V1EL2, VMA4; ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; K02150 V-type H+-transporting ATPase subunit E (A)"	Oxidative phosphorylation (ko00190);; Phagosome (ko04145);; Synaptic vesicle cycle (ko04721);; Collecting duct acid secretion (ko04966);; Vibrio cholerae infection (ko05110);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Rheumatoid arthritis (ko05323)	[C]	Energy production and conversion	ATP synthase (E/31 kDa) subunit	V-type proton ATPase subunit E 2 GN=ATP6V1E2 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: V-type proton ATPase subunit E 2 [Mustela putorius furo] 
ENSG00000250673(RP11-6L6.2)	--	0.023568	1	0	0	0	0	0	0	0.0230181	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Reeler domain	Ferric-chelate reductase 1 GN=FRRS1 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: uncharacterized protein LOC102150014 [Equus caballus]
ENSG00000250722(SELENOP)	--	0.453934049	14	0.710265891	26	0.325396137	11	0.200319171	6	0.43141023	11	0.210095356	7	--	--	--	0.847355391	-1.156273676	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	"Selenoprotein P, N terminal region"	Selenoprotein P (Precursor) GN=SEPP1 OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: LOW QUALITY PROTEIN: selenoprotein P [Ceratotherium simum simum]
ENSG00000250799(PRODH2)	--	0.034882673	1	0	0	0	0	0.103664943	3	0.358763793	10	0.668611	13	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	--	"K11394|0|hsa:58510|PRODH2, HSPOX1; proline dehydrogenase (oxidase) 2 (EC:1.5.5.2); K11394 hydroxyproline oxidase [EC:1.5.-.-] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	Proline dehydrogenase	Probable proline dehydrogenase 2 GN=PRODH2 OS=Homo sapiens (Human) PE=2 SV=1	E	Amino acid transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: probable proline dehydrogenase 2 [Galeopterus variegatus]
ENSG00000251192(ZNF674)	--	1.92110786	102	1.181144	96	2.125938316	81	1.239010304	62	1.46464543	74	2.61105555	100	0.486523475	-0.734712845	normal	0.921377276	-0.389918457	normal	0.94886967	0.290819784	normal	0.62291914	-0.26156465	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:641339|ZNF674, MRX92, ZNF673B; zinc finger protein 674; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain)"	Zinc finger protein 674 GN=ZNF674 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 674 isoform X1 [Equus przewalskii] 
ENSG00000251247(ZNF345)	--	0.322503464	13	0.078993501	3	0.192048298	8	0.300838028	15	0.299144931	11	0.378216597	15	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Transposase zinc-ribbon domain;; Zinc ribbon domain;; BED zinc finger;; TFIIH C1-like domain;; Probable zinc-binding domain;; Nicotinate phosphoribosyltransferase (NAPRTase) family"	Zinc finger protein 345 GN=ZNF345 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: zinc finger protein 865-like [Bubalus bubalis]
ENSG00000251258(RFPL4B)	--	0.0339238	1	0	0	0	0	0.0666039	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"SPRY domain;; zinc finger of C3HC4-type, RING;; Ring finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	Ret finger protein-like 4B GN=RFPL4B OS=Homo sapiens (Human) PE=2 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ret finger protein-like 4B [Orcinus orca]
ENSG00000251322(SHANK3)	--	3.874828221	884	3.225347405	804	3.39333	836	2.96071245	683	3.25554191	699	2.312623708	543	0.709445508	-0.402195229	normal	0.945135722	-0.222879556	normal	0.044950374	-0.629418193	normal	0.017454428	-0.412635173	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K15009|0|hsa:85358|SHANK3, DEL22q13.3, PROSAP2, PSAP2, SCZD15, SPANK-2; SH3 and multiple ankyrin repeat domains 3; K15009 SH3 and multiple ankyrin repeat domains protein (A)"	Glutamatergic synapse (ko04724)	[R]	General function prediction only	Ankyrin repeats (3 copies);; SAM domain (Sterile alpha motif);; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat;; SAM domain (Sterile alpha motif);; Ankyrin repeat;; Variant SH3 domain;; Variant SH3 domain;; PDZ domain (Also known as DHR or GLGF);; SH3 domain	SH3 and multiple ankyrin repeat domains protein 3 GN=SHANK3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SH3 and multiple ankyrin repeat domains protein 3 [Odobenus rosmarus divergens]
ENSG00000251369(ZNF550)	--	3.179517701	262	3.807031068	279	3.871969499	323	2.935999056	242	3.688722001	300	3.974812218	324	0.957624393	-0.144509917	normal	0.963643476	0.082837761	normal	0.968284922	-0.003813965	normal	0.974200785	-0.016637982	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|pps:100969395|ZNF550, ZNF416; zinc finger protein 550; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Phorbol esters/diacylglycerol binding domain (C1 domain);; C1-like domain"	Zinc finger protein 550 GN=ZNF550 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: zinc finger protein 550 [Galeopterus variegatus]
ENSG00000251493(FOXD1)	--	4.01751	120	3.66335	112	2.55069	80	7.96429	243	5.6891	172	5.07351	155	0.001312535	0.978119781	normal	0.527713692	0.590998892	normal	0.022571151	0.933011989	normal	0.019529124	0.846141429	normal	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K09397|3.30875e-78|hsa:2297|FOXD1, FKHL8, FREAC-4, FREAC4; forkhead box D1; K09397 forkhead box protein D (A)"	--	[K]	Transcription	Fork head domain	Forkhead box protein D1 GN=FOXD1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: forkhead box protein D1 [Lipotes vexillifer]
ENSG00000253148(RGS21)	--	0	0	0	0	0	0	0.0408003	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K16449|4.11917e-108|hsa:431704|RGS21; regulator of G-protein signaling 21; K16449 regulator of G-protein signaling (A)	--	[T]	Signal transduction mechanisms	Regulator of G protein signaling domain	Regulator of G-protein signaling 21 GN=RGS21 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: regulator of G-protein signaling 21 [Ailuropoda melanoleuca]
ENSG00000253250(C8orf88)	--	3.79387	49	2.71917	35	4.58651	59	3.7136	49	2.38825	31	1.90594	25	0.979323556	-0.029894894	normal	0.980605809	-0.18788152	normal	0.148221573	-1.198518312	normal	0.465365286	-0.468292508	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C8orf88 GN=C8orf88 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C8orf88 homolog [Equus przewalskii]
ENSG00000253276(CCDC71L)	--	11.90906	476	10.97437	463	8.24111	368	17.87587	757	19.64543	846	19.29693	780	0.043298979	0.63685618	normal	0.000346129	0.846144958	normal	4.19E-07	1.072379762	up	1.98E-07	0.845061651	normal	--	--	--	--	--	--	--	Coiled-coil domain-containing protein 71L	Coiled-coil domain-containing protein 71L GN=CCDC71L OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	"PREDICTED: coiled-coil domain-containing protein 71L, partial [Pteropus alecto]"
ENSG00000253304(TMEM200B)	--	1.07165	46	0.836198	37	0.75931	33	0.899789	39	0.79022	34	0.848658	37	0.974959528	-0.259563989	normal	0.980675736	-0.137550189	normal	0.981635155	0.150261725	normal	0.925424233	-0.098371339	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterised conserved protein (DUF2371)	Transmembrane protein 200B GN=TMEM200B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 200B [Trichechus manatus latirostris]
ENSG00000253309(SERPINE3)	--	0	0	0.0941845	2	0	0	0.290578146	7	0.0459935	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[V]	Defense mechanisms	Serpin (serine protease inhibitor)	Serpin E3 (Precursor) GN=SERPINE3 OS=Homo sapiens (Human) PE=2 SV=2	V	Defense mechanisms	PREDICTED: serpin E3 [Galeopterus variegatus]
ENSG00000253313(C1orf210)	--	0.098946439	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Leucine-rich repeat family 19 TM domain	Type III endosome membrane protein TEMP {ECO:0000250|UniProtKB:Q9CQM1} GN=C1orf210 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: putative uncharacterized protein C1orf210 homolog [Galeopterus variegatus] 
ENSG00000253368(TRNP1)	--	173.37013	3637	149.90244	2983	168.72924	3575	127.70386	2732	91.76550276	1922	97.82072	2029	0.655876131	-0.443406735	normal	0.020032902	-0.655164854	normal	0.000114062	-0.824996242	normal	0.001287682	-0.631365694	normal	--	--	--	--	--	--	--	--	TMF-regulated nuclear protein 1 GN=TRNP1 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: TMF-regulated nuclear protein 1 [Odobenus rosmarus divergens]
ENSG00000253457(SMIM18)	--	0	0	0	0	0	0	0	0	0.149157	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Small integral membrane protein 18 GN=SMIM18 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 18 [Galeopterus variegatus]
ENSG00000253598(SLC10A5)	--	0.447097	16	0.670825	24	0.140448	4	0.277039	10	0.460534	16	0.360737	13	--	--	--	0.975465677	-0.562691185	normal	--	--	--	--	--	--	[R]	General function prediction only	Cellular Component: membrane (GO:0016020);; 	"K14343|0|hsa:347051|SLC10A5, P5; solute carrier family 10, member 5; K14343 solute carrier family 10 (sodium/bile acid cotransporter), member 3/5 (A)"	--	[P]	Inorganic ion transport and metabolism	Sodium Bile acid symporter family	Sodium/bile acid cotransporter 5 (Precursor) GN=SLC10A5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium/bile acid cotransporter 5 [Ceratotherium simum simum]
ENSG00000253626(EIF5AL1)	--	0.0259174	2	0.012893	1	0.012846	0	0.0129131	1	0	0	0.0257058	2	--	--	--	--	--	--	--	--	--	--	--	--	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Molecular Function: translation elongation factor activity (GO:0003746);; Biological Process: translational frameshifting (GO:0006452);; Molecular Function: ribosome binding (GO:0043022);; Biological Process: positive regulation of translational elongation (GO:0045901);; Biological Process: positive regulation of translational termination (GO:0045905);; 	--	--	[J]	"Translation, ribosomal structure and biogenesis"	"Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold"	Eukaryotic translation initiation factor 5A-1-like GN=EIF5AL1 OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: eukaryotic translation initiation factor 5A-1 isoform X3 [Mustela putorius furo]
ENSG00000253710(ALG11)	--	9.65905247	1014	8.857111	1051	10.095196	973	7.650843326	819	7.796326388	824	8.27498128	878	0.851808221	-0.338382759	normal	0.797460735	-0.37186702	normal	0.967261232	-0.156254523	normal	0.104715461	-0.29022313	normal	[M]	Cell wall/membrane/envelope biogenesis	--	"K03844|0|ptr:452735|ALG11, UTP14C; ALG11, alpha-1,2-mannosyltransferase; K03844 alpha-1,2-mannosyltransferase [EC:2.4.1.131] (A)"	N-Glycan biosynthesis (ko00510)	[M]	Cell wall/membrane/envelope biogenesis	Glycosyl transferases group 1;; Glycosyl transferases group 1	"GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase GN=ALG11 OS=Homo sapiens (Human) PE=1 SV=2"	M	Cell wall/membrane/envelope biogenesis	"PREDICTED: GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase [Ceratotherium simum simum]"
ENSG00000253719(ATXN7L3B)	--	11.1138	1341	12.8193	1542	12.2258	1443	15.0282	1827	15.7532	1902	15.2465	1844	0.694478675	0.414926451	normal	0.936312228	0.281039364	normal	0.865928822	0.345155162	normal	0.029963012	0.344254303	normal	--	--	--	--	--	--	--	--	Putative ataxin-7-like protein 3B GN=ATXN7L3B OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	PREDICTED: putative ataxin-7-like protein 3B [Orycteropus afer afer] 
ENSG00000253729(PRKDC)	--	62.58673434	16475	61.56432946	16327	64.11064335	16820	65.95662593	17394	65.49272212	17092	58.51031386	15417	0.997488824	0.047474702	normal	0.997343858	0.044630896	normal	0.996298219	-0.133934507	normal	0.972789215	-0.013333344	normal	[TDBLU]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Chromatin structure and dynamics;; Replication, recombination and repair;; Intracellular trafficking, secretion, and vesicular transport"	Molecular Function: DNA binding (GO:0003677);; Molecular Function: DNA-dependent protein kinase activity (GO:0004677);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: nucleus (GO:0005634);; Biological Process: double-strand break repair via nonhomologous end joining (GO:0006303);; Molecular Function: kinase activity (GO:0016301);; 	"K06642|0|pps:100981342|PRKDC; protein kinase, DNA-activated, catalytic polypeptide; K06642 DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1] (A)"	Non-homologous end-joining (ko03450);; Cell cycle (ko04110)	[L]	"Replication, recombination and repair"	NUC194 domain;; FAT domain;; Phosphatidylinositol 3- and 4-kinase;; FATC domain	DNA-dependent protein kinase catalytic subunit GN=PRKDC OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: DNA-dependent protein kinase catalytic subunit isoform 1 [Ceratotherium simum simum]
ENSG00000253958(CLDN23)	--	7.74296	257	7.15884	245	7.57609	262	6.66079	223	6.8119	227	6.6569	223	0.936966384	-0.234053169	normal	0.95845569	-0.130677752	normal	0.935096492	-0.239315554	normal	0.542009465	-0.204054636	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	"K06087|2.36471e-164|hsa:137075|CLDN23, CLDNL, hCG1646163; claudin 23; K06087 claudin (A)"	Cell adhesion molecules (CAMs) (ko04514);; Tight junction (ko04530);; Leukocyte transendothelial migration (ko04670);; Hepatitis C (ko05160)	--	--	PMP-22/EMP/MP20/Claudin family;; PMP-22/EMP/MP20/Claudin tight junction	Claudin-23 GN=CLDN23 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: claudin-23 [Chrysochloris asiatica]
ENSG00000254004(ZNF260)	--	11.41406136	1019	12.05794862	1054	11.320856	1006	12.75144054	1135	12.16468974	1071	11.934306	1067	0.974016004	0.124528024	normal	0.979796999	0.0016547	normal	0.977796282	0.076526713	normal	0.795933666	0.066702682	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain;; Transposase zinc-ribbon domain"	Zinc finger protein 260 GN=ZNF260 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 850-like [Mustela putorius furo]
ENSG00000254087(LYN)	--	15.63971465	941	18.4952004	1115	15.43341948	958	19.64519466	1235	21.04964438	1312	16.7158719	1058	0.818070743	0.360896461	normal	0.958104758	0.213030855	normal	0.971890468	0.134748142	normal	0.193675586	0.236592671	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K05854|0|ggo:101145340|LYN; tyrosine-protein kinase Lyn isoform 1; K05854 tyrosine-protein kinase Lyn [EC:2.7.10.2] (A)	Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; Platelet activation (ko04611);; B cell receptor signaling pathway (ko04662);; Fc epsilon RI signaling pathway (ko04664);; Fc gamma R-mediated phagocytosis (ko04666);; Long-term depression (ko04730);; Epstein-Barr virus infection (ko05169);; Viral carcinogenesis (ko05203)	[T]	Signal transduction mechanisms	Protein tyrosine kinase;; Protein kinase domain;; SH2 domain;; SH3 domain;; Variant SH3 domain;; Variant SH3 domain	Tyrosine-protein kinase Lyn GN=LYN OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase Lyn isoform 1 [Odobenus rosmarus divergens]
ENSG00000254206(NPIPB11)	--	0.9914971	65	0.802365308	51	1.133932563	74	0.9351141	61	0.626279073	40	0.818297022	55	0.974292922	-0.119545068	normal	0.9628982	-0.359844368	normal	0.933190345	-0.426244304	normal	0.623059952	-0.305664301	normal	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B11 GN=NPIPB11 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000254440(PBOV1)	--	0	0	0.0554953	2	0.110467	3	0.0269434	1	0	0	0.107332	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Prostate and breast cancer overexpressed gene 1 protein GN=PBOV1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: prostate and breast cancer overexpressed 1 [Leptonychotes weddellii]
ENSG00000254469(RP11-849H4.2)	--	2.449822081	112	1.860316	82	3.14236335	31	2.161539783	30	2.857139373	37	1.883928551	25	2.80E-07	-1.877935148	down	0.048357502	-1.137481541	normal	0.980897168	-0.302186039	normal	0.172985525	-1.313237984	normal	--	--	Biological Process: single strand break repair (GO:0000012);; Molecular Function: damaged DNA binding (GO:0003684);; Cellular Component: nucleus (GO:0005634);; 	K10803|3.35389e-128|pps:100993810|DNA repair protein XRCC1-like; K10803 DNA-repair protein XRCC1 (A)	Base excision repair (ko03410)	--	--	XRCC1 N terminal domain	Putative short transient receptor potential channel 2-like protein OS=Homo sapiens (Human) PE=5 SV=1	L	"Replication, recombination and repair"	PREDICTED: short transient receptor potential channel 2-like isoform X1 [Myotis brandtii] 
ENSG00000254470(AP5B1)	--	8.89635	1126	10.1013	1341	9.67541	1278	9.46729	1180	9.16197	1151	9.88677	1244	0.98070284	0.036698852	normal	0.948144431	-0.241553593	normal	0.981477908	-0.047136256	normal	0.711480135	-0.088040781	normal	--	--	--	--	--	--	--	--	AP-5 complex subunit beta-1 GN=AP5B1 OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: LOW QUALITY PROTEIN: AP-5 complex subunit beta-1 [Tursiops truncatus]
ENSG00000254535(PABPC4L)	--	0.289026482	18	0.09621332	6	0.37119958	22	0.82783	53	1.694	107	0.763697219	48	0.050152454	1.451865911	normal	0	3.833342845	up	0.52633939	1.066473514	normal	0.015966317	2.157210419	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K13126|0|pps:100973046|PABPC4L; poly(A) binding protein, cytoplasmic 4-like; K13126 polyadenylate-binding protein (A)"	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; RNA degradation (ko03018)	[AJ]	"RNA processing and modification;; Translation, ribosomal structure and biogenesis"	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Limkain b1;; Nup53/35/40-type RNA recognition motif;; Nup53/35/40-type RNA recognition motif;; RNA binding motif"	Polyadenylate-binding protein 4-like GN=PABPC4L OS=Homo sapiens (Human) PE=2 SV=1	A	RNA processing and modification	PREDICTED: polyadenylate-binding protein 4-like [Galeopterus variegatus]
ENSG00000254598(CSNK2A3)	--	0.204851	5	0.16371	4	0.243602	5	0.260798	6	0.278039	6	0.487122	12	--	--	--	--	--	--	--	--	--	--	--	--	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	--	--	[TDK]	"Signal transduction mechanisms;; Cell cycle control, cell division, chromosome partitioning;; Transcription"	Protein kinase domain;; Protein tyrosine kinase;; Phosphotransferase enzyme family	Casein kinase II subunit alpha 3 GN=CSNK2A3 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: casein kinase II subunit alpha isoform X1 [Mustela putorius furo] 
ENSG00000254636(ARMS2)	--	0.260061	3	0	0	0	0	0.0844132	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Age-related maculopathy susceptibility protein 2 GN=ARMS2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000254656(RTL1)	--	0.0111327	1	0.0447396	4	0.0108637	0	0	0	0.0430566	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[L]	"Replication, recombination and repair"	--	--	--	[R]	General function prediction only	gag-polyprotein putative aspartyl protease;; Retrotransposon gag protein	Retrotransposon-like protein 1 GN=RTL1 OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: retrotransposon-like protein 1 [Galeopterus variegatus]
ENSG00000254726(MEX3A)	--	2.51348	302	1.622498	198	2.38821	289	2.6964	323	3.90095	463	2.27522	274	0.966103584	0.065829493	normal	2.28E-07	1.197928674	up	0.964470603	-0.084729628	normal	0.402102147	0.40493887	normal	--	--	Molecular Function: RNA binding (GO:0003723);; Molecular Function: metal ion binding (GO:0046872);; 	"K15686|0|ptr:457383|MEX3A, RKHD4; mex-3 RNA binding family member A; K15686 RNA-binding protein MEX3 (A)"	--	[R]	General function prediction only	"KH domain;; KH domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RNA-binding protein MEX3A GN=MEX3A OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RNA-binding protein MEX3A [Camelus bactrianus]
ENSG00000254772(EEF1G)	--	1133.87	30010	1025.83	27393	1042.42	27859	1165.51	31122	1202.47	31463	1141.74	30265	0.99853935	0.021658104	normal	0.9969233	0.17841321	normal	0.997998371	0.111209642	normal	0.721646603	0.101708485	normal	--	--	Molecular Function: translation elongation factor activity (GO:0003746);; Molecular Function: protein binding (GO:0005515);; Biological Process: translational elongation (GO:0006414);; 	"K03233|0|hsa:1937|EEF1G, EF1G, GIG35; eukaryotic translation elongation factor 1 gamma; K03233 elongation factor 1-gamma (A)"	Legionellosis (ko05134)	[O]	"Posttranslational modification, protein turnover, chaperones"	"Elongation factor 1 gamma, conserved domain;; Glutathione S-transferase, N-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, C-terminal domain;; Glutathione S-transferase, N-terminal domain"	Elongation factor 1-gamma GN=EEF1G OS=Homo sapiens (Human) PE=1 SV=3	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: elongation factor 1-gamma [Galeopterus variegatus]
ENSG00000254827(SLC22A18AS)	--	4.734835	51	5.038559	49	3.228691138	33	4.31283	52	5.733287	51	3.562770004	36	0.97879347	-0.002736253	normal	0.977583258	0.035223371	normal	0.982467979	0.11231049	normal	0.975535726	0.040817167	normal	--	--	--	--	--	--	--	--	Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene B protein GN=SLC22A18AS OS=Homo sapiens (Human) PE=2 SV=3	P	Inorganic ion transport and metabolism	--
ENSG00000254852(NPIPA2)	--	0.474020583	9	0.520481496	10	0.205713496	3	0.155190185	3	0.153298642	2	0.257942624	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member A2 GN=NPIPA2 OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000254858(MPV17L2)	--	8.99866	211	8.52211	200	9.18848	219	6.59326	154	7.41052	172	7.62015	180	0.702882727	-0.481026035	normal	0.938882995	-0.237082764	normal	0.918631512	-0.289020302	normal	0.301205634	-0.336787284	normal	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	K13348|7.98293e-142|ptr:748969|MPV17L2; MPV17 mitochondrial membrane protein-like 2; K13348 protein Mpv17 (A)	Peroxisome (ko04146)	[R]	General function prediction only	Mpv17 / PMP22 family	Mpv17-like protein 2 GN=MPV17L2 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: mpv17-like protein 2 [Sus scrofa]
ENSG00000254893(AC113404.1)	--	1.264349103	32	0.825271707	21	1.496186437	37	1.829611631	47	2.136050115	54	1.564247338	40	0.951987189	0.503700305	normal	0.134179237	1.281679491	normal	0.981249613	0.100241992	normal	0.295405983	0.62687325	normal	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07836|1.51532e-131|tup:102472381|RAP1B; RAP1B, member of RAS oncogene family; K07836 Ras-related protein Rap-1B (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Chemokine signaling pathway (ko04062);; Focal adhesion (ko04510);; Platelet activation (ko04611);; Leukocyte transendothelial migration (ko04670);; Long-term potentiation (ko04720);; Neurotrophin signaling pathway (ko04722);; Pancreatic secretion (ko04972);; Renal cell carcinoma (ko05211)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; 50S ribosome-binding GTPase	Ras-related protein Rap-1b-like protein (Precursor) OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"Ras-related protein Rap-1b, partial [Bos mutus]"
ENSG00000254999(BRK1)	--	125.382	2185	127.605	2258	122.091	2134	130.88	2319	119.378	2069	114.605	2003	0.987188892	0.054999735	normal	0.980701561	-0.147435201	normal	0.984439334	-0.099616317	normal	0.800513651	-0.063125774	normal	--	--	--	"K05752|1.74114e-48|ptr:100608101|BRK1; BRICK1, SCAR/WAVE actin-nucleating complex subunit; K05752 chromosome 3 open reading frame 10 (A)"	Regulation of actin cytoskeleton (ko04810)	--	--	--	Protein BRICK1 GN=BRK1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: probable protein BRICK1-like isoform 1 [Sus scrofa]
ENSG00000255112(CHMP1B)	--	22.4003	1043	31.7009	1478	23.7812	1099	17.2479	808	17.9232	831	26.1212	1218	0.721491979	-0.398475209	normal	0.000119162	-0.850974352	normal	0.973217412	0.139848437	normal	0.366984272	-0.361768541	normal	[N]	Cell motility	Biological Process: vacuolar transport (GO:0007034);; 	K12197|2.31983e-112|umr:103673369|CHMP1B; charged multivesicular body protein 1B; K12197 charged multivesicular body protein 1 (A)	Endocytosis (ko04144)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Snf7	Charged multivesicular body protein 1b GN=CHMP1B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: charged multivesicular body protein 1b [Chrysochloris asiatica]
ENSG00000255150(EID3)	--	4.1333	104	11.394	290	6.86953	174	2.3715	60	3.45404	86	4.49812	113	0.310459958	-0.808450907	normal	3.12E-12	-1.757185022	down	0.424577752	-0.624270591	normal	0.181467214	-1.15267524	normal	[S]	Function unknown	--	--	--	[S]	Function unknown	Nse4 C-terminal;; Binding domain of Nse4/EID3 to Nse3-MAGE	EP300-interacting inhibitor of differentiation 3 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: EP300-interacting inhibitor of differentiation 3 [Camelus bactrianus]
ENSG00000255181(CCDC166)	--	0	0	0	0	0	0	0.0577779	1	0	0	0.0577626	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4515)	Coiled-coil domain-containing protein 166 GN=CCDC166 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: coiled-coil domain-containing protein 166 [Trichechus manatus latirostris]
ENSG00000255302(EID1)	--	59.4788343	2146	61.16254585	2215	60.198582	2164	70.3419904	2490	70.307019	2486	60.639769	2153	0.976989021	0.183541331	normal	0.981986232	0.144999556	normal	0.987513521	-0.015632669	normal	0.625053835	0.106118094	normal	--	--	--	--	--	--	--	--	EP300-interacting inhibitor of differentiation 1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: EP300-interacting inhibitor of differentiation 1 [Galeopterus variegatus]
ENSG00000255346(NOX5)	--	0.292408296	26	0.146724227	24	0.172374492	14	0.466885093	34	0.487069425	45	0.382348247	31	0.978652606	0.338651148	normal	0.820300542	0.845976467	normal	0.837699707	1.059879165	normal	0.23088302	0.759192006	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	--	--	[PQ]	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	Ferric reductase NAD binding domain;; FAD-binding domain;; Ferric reductase like transmembrane component;; EF-hand domain;; EF hand;; EF hand;; EF-hand domain pair;; EF-hand domain pair	NADPH oxidase 5 GN=NOX5 OS=Homo sapiens (Human) PE=1 SV=1	PQ	"Inorganic ion transport and metabolism;; Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: NADPH oxidase 5 isoform 1 [Ceratotherium simum simum]
ENSG00000255398(HCAR3)	--	0.0553557	2	0	0	0.0272326	0	0.0552547	2	0	0	0.110058	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K08402|0|hsa:8843|HCAR3, GPR109B, HCA3, HM74, PUMAG, Puma-g; hydroxycarboxylic acid receptor 3; K08402 G protein-coupled receptor 109 (A)"	cAMP signaling pathway (ko04024)	--	--	7 transmembrane receptor (rhodopsin family)	Hydroxycarboxylic acid receptor 3 GN=HCAR3 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: hydroxycarboxylic acid receptor 3 [Equus caballus] 
ENSG00000255423(EBLN2)	--	0.993567	26	1.57032	41	1.60237	41	0.869607	23	1.29868	34	1.29121	34	0.985843369	-0.195422705	normal	0.974813168	-0.280150845	normal	0.976703619	-0.267529014	normal	0.745258319	-0.266794227	normal	--	--	--	--	--	--	--	Borna disease virus P40 protein	Endogenous Bornavirus-like nucleoprotein 2 GN=EBLN2 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: endogenous Bornavirus-like nucleoprotein 1-like [Chrysochloris asiatica]
ENSG00000255524(NPIPB8)	--	0.170997028	1	0.505173031	3	0.493267088	2	0.162140027	1	0.827077023	4	0.330059112	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Nuclear pore complex interacting protein (NPIP)	Nuclear pore complex-interacting protein family member B8 GN=NPIPB8 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	hypothetical protein CB1_000307022 [Camelus ferus]
ENSG00000255587(RAB44)	--	0.011414185	1	0.011234067	1	0.055076948	4	0.045933803	4	0.044458355	3	0.0605332	6	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	--	--	--	--	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Gtr1/RagA G protein conserved region;; 50S ribosome-binding GTPase	Ras-related protein Rab-44 GN=RAB44 OS=Homo sapiens (Human) PE=3 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-44 [Camelus dromedarius]
ENSG00000255690(TRIL)	--	0	0	0	0	0.0126545	0	0.0130812	1	0.0254469	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies);; Leucine Rich Repeat;; Leucine-rich repeat;; Leucine rich repeats (6 copies);; Leucine rich repeat;; Leucine rich repeat C-terminal domain	TLR4 interactor with leucine rich repeats (Precursor) GN=TRIL OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: TLR4 interactor with leucine rich repeats [Ceratotherium simum simum]
ENSG00000255823(MTRNR2L8)	--	0.0482683	1	0.245019	5	0	0	0	0	0	0	0.140631	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Humanin-like 8 {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=1	--	--	--
ENSG00000255837(TAS2R20)	--	0.172754	3	0.467435	8	0.876013	14	0.343658	6	0.95114	16	0.343653	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:259295|TAS2R20, T2R20, T2R49, T2R56, TAS2R49; taste receptor, type 2, member 20; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 20 GN=TAS2R20 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 20-like [Tupaia chinensis]
ENSG00000255974(CYP2A6)	--	0.0307451	1	0.0609936	2	0.0298535	0	0	0	0.0299283	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: iron ion binding (GO:0005506);; Molecular Function: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705);; Molecular Function: heme binding (GO:0020037);; Biological Process: oxidation-reduction process (GO:0055114);; "	"K17683|0|hsa:1548|CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB; cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1); K17683 cytochrome P450, family 2, subfamily A, polypeptide 6 [EC:1.14.13.-] (A)"	Caffeine metabolism (ko00232);; Retinol metabolism (ko00830);; Metabolism of xenobiotics by cytochrome P450 (ko00980);; Drug metabolism - cytochrome P450 (ko00982);; Drug metabolism - other enzymes (ko00983);; Chemical carcinogenesis (ko05204)	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Cytochrome P450	Cytochrome P450 2A6 GN=CYP2A6 OS=Homo sapiens (Human) PE=1 SV=3	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: cytochrome P450 2A13-like isoform 1 [Equus caballus] 
ENSG00000256043(CTSO)	--	1.03431	41	1.163090226	51	0.570257099	24	2.308382	94	1.397966828	61	1.682700966	74	0.026413252	1.137323651	normal	0.968910546	0.230625887	normal	0.001656316	1.557556467	up	0.03218535	0.958015265	normal	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: cysteine-type peptidase activity (GO:0008234);; 	"K01374|0|hsa:1519|CTSO, CTSO1; cathepsin O (EC:3.4.22.42); K01374 cathepsin O [EC:3.4.22.42] (A)"	Lysosome (ko04142)	[O]	"Posttranslational modification, protein turnover, chaperones"	Papain family cysteine protease;; Peptidase C1-like family	Cathepsin O (Precursor) GN=CTSO OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: cathepsin O [Odobenus rosmarus divergens]
ENSG00000256061(DYX1C1)	--	4.120176413	136	2.764727402	94	3.863152846	123	4.939706333	165	4.847213484	164	4.631992401	163	0.943128106	0.245506087	normal	0.138986926	0.772021018	normal	0.872461075	0.393704239	normal	0.188734353	0.457964904	normal	--	--	--	--	--	[R]	General function prediction only	TPR repeat;; CS domain;; Tetratricopeptide repeat;; Tetratricopeptide repeat;; Tetratricopeptide repeat	Dyslexia susceptibility 1 candidate gene 1 protein GN=DYX1C1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: dyslexia susceptibility 1 candidate gene 1 protein homolog isoform 1 [Equus caballus]
ENSG00000256162(SMLR1)	--	0	0	0	0	0	0	0.0499225	2	0.0487044	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Small leucine-rich protein 1 GN=SMLR1 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: small leucine-rich protein 1 [Galeopterus variegatus]
ENSG00000256188(TAS2R30)	--	0.0866989	2	0.0434293	1	0.217278	4	0.0431089	1	0.211153	4	0.0861747	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:259293|TAS2R30, T2R30, T2R47, TAS2R47; taste receptor, type 2, member 30; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 30 GN=TAS2R30 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 46-like [Panthera tigris altaica]
ENSG00000256222(MTRNR2L3)	--	0	0	0	0	0.0832365	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Humanin-like 3 {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=1	--	--	--
ENSG00000256229(ZNF486)	--	0	0	0	0	0	0	0	0	0.0289137	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:90649|ZNF486, KRBO2; zinc finger protein 486; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain;; Probable zinc-binding domain;; C1-like domain"	Zinc finger protein 486 GN=ZNF486 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000256235(SMIM3)	--	2.41482	102	2.66015	114	2.88039	123	2.58868	110	2.39753	101	1.40693	60	0.969070747	0.076985334	normal	0.958320794	-0.193377735	normal	0.020207539	-1.025480746	normal	0.445750801	-0.345565693	normal	--	--	--	--	--	--	--	--	Small integral membrane protein 3 GN=SMIM3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 3 isoform 1 [Dasypus novemcinctus] 
ENSG00000256269(HMBS)	--	18.52569344	552	16.9484552	512	21.39171625	614	20.20259767	584	21.6263974	636	18.71194047	550	0.971937951	0.050331635	normal	0.901106502	0.290684755	normal	0.958557908	-0.166664517	normal	0.861626063	0.055981594	normal	[H]	Coenzyme transport and metabolism	Molecular Function: hydroxymethylbilane synthase activity (GO:0004418);; Biological Process: tetrapyrrole biosynthetic process (GO:0033014);; 	"K01749|0|hsa:3145|HMBS, PBG-D, PBGD, PORC, UPS; hydroxymethylbilane synthase (EC:2.5.1.61); K01749 hydroxymethylbilane synthase [EC:2.5.1.61] (A)"	Porphyrin and chlorophyll metabolism (ko00860)	[H]	Coenzyme transport and metabolism	"Porphobilinogen deaminase, dipyromethane cofactor binding domain;; Porphobilinogen deaminase, C-terminal domain"	Porphobilinogen deaminase GN=HMBS OS=Homo sapiens (Human) PE=1 SV=2	H	Coenzyme transport and metabolism	PREDICTED: porphobilinogen deaminase isoform X1 [Oryctolagus cuniculus]
ENSG00000256294(ZNF225)	--	2.472075151	161	1.884856829	121	1.651634	102	2.234122432	155	2.98803586	200	2.573882653	177	0.965279923	-0.084799875	normal	0.189898432	0.696727433	normal	0.099753022	0.778025589	normal	0.181300962	0.449130178	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7768|ZNF225; zinc finger protein 225; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; BolA-like protein;; Probable zinc-binding domain;; Zinc-finger of C2H2 type"	Zinc finger protein 225 GN=ZNF225 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 234 [Camelus ferus]
ENSG00000256394(ASIC5)	--	0.0374987	1	0.0376952	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sodium channel activity (GO:0005272);; Biological Process: sodium ion transport (GO:0006814);; Cellular Component: membrane (GO:0016020);; 	"K04832|0|hsa:51802|ASIC5, ACCN5, HINAC, INAC; acid-sensing (proton-gated) ion channel family member 5; K04832 acid-sensing ion channel 5 (A)"	Inflammatory mediator regulation of TRP channels (ko04750)	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Amiloride-sensitive sodium channel	Acid-sensing ion channel 5 GN=ASIC5 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: acid-sensing ion channel 5 [Ursus maritimus]
ENSG00000256436(TAS2R31)	--	0.173401	2	0.349623	4	0.173306	1	0.16492	2	0	0	0.941398	11	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; Biological Process: sensory perception of taste (GO:0050909);; 	"K08474|0|hsa:259290|TAS2R31, T2R31, T2R44, T2R53, TAS2R44; taste receptor, type 2, member 31; K08474 taste receptor type 2 (A)"	Taste transduction (ko04742)	--	--	Mammalian taste receptor protein (TAS2R)	Taste receptor type 2 member 31 GN=TAS2R31 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: taste receptor type 2 member 20-like [Tupaia chinensis]
ENSG00000256463(SALL3)	--	0	0	0	0	0	0	0.010353013	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Sal-like protein 3 GN=SALL3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: sal-like protein 3 [Odobenus rosmarus divergens]
ENSG00000256525(POLG2)	--	9.903621	538	9.442204023	473	9.448648	515	8.11005929	440	9.815431	546	7.388219602	480	0.870917969	-0.31992259	normal	0.951842953	0.185083071	normal	0.966057856	-0.10949634	normal	0.798840088	-0.078656521	normal	[J]	"Translation, ribosomal structure and biogenesis"	--	"K02333|0|hsa:11232|POLG2, HP55, MTPOLB, PEOA4, POLB, POLG-BETA, POLGB; polymerase (DNA directed), gamma 2, accessory subunit (EC:2.7.7.7); K02333 DNA polymerase gamma 2 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	Anticodon binding domain	"DNA polymerase subunit gamma-2, mitochondrial (Precursor) GN=POLG2 OS=Homo sapiens (Human) PE=1 SV=1"	L	"Replication, recombination and repair"	"PREDICTED: DNA polymerase subunit gamma-2, mitochondrial isoform X2 [Myotis brandtii] "
ENSG00000256537(SMIM10L1)	--	5.53056	409	6.24294	466	5.96694	436	6.89644	523	6.05312	449	7.31295	543	0.868334237	0.322803274	normal	0.967586661	-0.074793769	normal	0.884860535	0.307375471	normal	0.46117442	0.187470245	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4560)	Small integral membrane protein 10 GN=SMIM10 OS=Homo sapiens (Human) PE=4 SV=4	S	Function unknown	PREDICTED: uncharacterized protein MGC39606-like [Ochotona princeps]
ENSG00000256683(ZNF350)	--	3.266110001	145	3.613607463	171	2.583278277	130	3.458651	151	2.500226321	125	3.23234934	165	0.967757465	0.0273791	normal	0.777318686	-0.468626188	normal	0.911016235	0.332224922	normal	0.955958996	-0.037644075	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:59348|ZNF350, ZBRK1, ZFQR; zinc finger protein 350; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger"	Zinc finger protein 350 GN=ZNF350 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 350-like [Galeopterus variegatus]
ENSG00000256713(PGA5)	--	0	0	0.0783549	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: aspartic-type endopeptidase activity (GO:0004190);; Biological Process: proteolysis (GO:0006508);; 	"K06002|0|hsa:5222|PGA5; pepsinogen 5, group I (pepsinogen A) (EC:3.4.23.1); K06002 pepsin A [EC:3.4.23.1] (A)"	Protein digestion and absorption (ko04974)	[O]	"Posttranslational modification, protein turnover, chaperones"	Eukaryotic aspartyl protease;; Xylanase inhibitor N-terminal;; A1 Propeptide	Pepsin A-5 (Precursor) GN=PGA5 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: pepsin A isoform X1 [Orycteropus afer afer]
ENSG00000256762(STH)	--	0	0	0.31041	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Saitohin GN=STH OS=Homo sapiens (Human) PE=1 SV=1	--	--	PREDICTED: LOW QUALITY PROTEIN: saitohin [Loxodonta africana]
ENSG00000256771(ZNF253)	--	0.022070222	1	0.09198376	3	0	0	0.052511652	1	0.089693091	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:56242|ZNF253, BMZF-1, BMZF1, ZNF411; zinc finger protein 253; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; XPA protein N-terminal;; Zinc ribbon domain;; C1-like domain;; TFIIH C1-like domain"	Zinc finger protein 253 GN=ZNF253 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	hypothetical protein PANDA_017951 [Ailuropoda melanoleuca]
ENSG00000256806(C17orf100)	--	3.48794	106	2.15546	65	2.31199	70	2.12799	64	1.76691	53	1.83619	56	0.436192289	-0.744706685	normal	0.959808204	-0.307925195	normal	0.957221043	-0.322415688	normal	0.308059288	-0.50016822	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C17orf100 GN=C17orf100 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C17orf100 homolog [Pteropus alecto]
ENSG00000256812(CAPNS2)	--	0.0694847	1	0	0	0	0	0.136453	2	0.0678484	0	0.0688986	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	"K08584|3.44036e-142|ptr:100615020|CAPNS2; calpain, small subunit 2; K08584 calpain, small subunit 2 (A)"	--	[T]	Signal transduction mechanisms	EF-hand domain pair;; EF-hand domain;; EF hand;; EF-hand domain pair	Calpain small subunit 2 GN=CAPNS2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: calpain small subunit 2 [Felis catus]
ENSG00000256980(KHDC1L)	--	0.140221	1	0	0	0	0	0	0	0.272178	1	0.41153	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative KHDC1-like protein GN=KHDC1L OS=Homo sapiens (Human) PE=5 SV=1	R	General function prediction only	PREDICTED: KH homology domain-containing protein 1-like [Galeopterus variegatus] 
ENSG00000257017(HP)	--	0	0	0	0	0	0	0	0	0	0	0.136292015	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K16142|0|hsa:3240|HP, BP, HP2ALPHA2, HPA1S; haptoglobin; K16142 haptoglobin (A)"	--	[E]	Amino acid transport and metabolism	Trypsin	Haptoglobin beta chain (Precursor) GN=HP OS=Homo sapiens (Human) PE=1 SV=1	E	Amino acid transport and metabolism	PREDICTED: haptoglobin [Chrysochloris asiatica]
ENSG00000257093(KIAA1147)	--	5.830990742	805	5.972381364	835	5.690279	778	6.947503886	951	8.365307911	1137	7.166467609	987	0.952931813	0.209256527	normal	0.659104443	0.423298264	normal	0.857567509	0.334410078	normal	0.060891538	0.325675411	normal	--	--	--	--	--	[S]	Function unknown	Uncharacterized conserved protein (DUF2347);; Stabilization of polarity axis;; Transport protein Avl9	Protein LCHN GN=LCHN OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: protein LCHN [Odobenus rosmarus divergens]
ENSG00000257103(LSM14A)	--	72.83989307	3844	75.318467	3965	69.50545325	3756	82.28046525	4424	81.247443	4250	80.71279664	4077	0.985993959	0.171846724	normal	0.991031594	0.078686427	normal	0.989772501	0.10997694	normal	0.580031512	0.119335501	normal	--	--	--	"K18749|0|hsa:26065|LSM14A, C19orf13, FAM61A, RAP55, RAP55A; LSM14A, SCD6 homolog A (S. cerevisiae); K18749 protein LSM14 (A)"	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Scd6-like Sm domain;; FDF domain	Protein LSM14 homolog A GN=LSM14A OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: protein LSM14 homolog A isoform X2 [Mustela putorius furo] 
ENSG00000257115(OR11H12)	--	0.0921831	1	0	0	0	0	0	0	0.0899438	0	0.0916814	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:440153|OR11H12; olfactory receptor, family 11, subfamily H, member 12; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 11H12 GN=OR11H12 OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	"PREDICTED: olfactory receptor 11H12-like, partial [Tupaia chinensis]"
ENSG00000257127(CLLU1)	--	0	0	0	0	0	0	0	0	0.0158903	0	0.0162316	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Chronic lymphocytic leukemia up-regulated protein 1 GN=CLLU1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000257335(MGAM)	--	0.069789116	10	0.115584939	19	0.121716226	22	0.585369638	106	0.67889837	126	0.505948889	91	3.59E-14	3.191993715	up	9.92E-13	2.61556637	up	1.81E-06	1.968273041	up	4.82E-11	2.642160419	up	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	K12047|0|ptr:463789|MGAM; maltase-glucoamylase (alpha-glucosidase); K12047 maltase-glucoamylase [EC:3.2.1.20 3.2.1.3] (A)	Galactose metabolism (ko00052);; Starch and sucrose metabolism (ko00500);; Carbohydrate digestion and absorption (ko04973)	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 31;; Trefoil (P-type) domain;; Galactose mutarotase-like	Glucoamylase GN=MGAM OS=Homo sapiens (Human) PE=1 SV=5	G	Carbohydrate transport and metabolism	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein LOC100358478 [Oryctolagus cuniculus]
ENSG00000257743(MGAM2)	--	0	0	0	0	0.0143641	1	0	0	0.03736134	1	0.00715246	1	--	--	--	--	--	--	--	--	--	--	--	--	[G]	Carbohydrate transport and metabolism	"Molecular Function: hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553);; Biological Process: carbohydrate metabolic process (GO:0005975);; "	--	--	[G]	Carbohydrate transport and metabolism	Glycosyl hydrolases family 31;; Trefoil (P-type) domain;; Galactose mutarotase-like	Glucoamylase OS=Homo sapiens (Human) PE=2 SV=3	G	Carbohydrate transport and metabolism	"PREDICTED: LOW QUALITY PROTEIN: maltase-glucoamylase, intestinal-like [Galeopterus variegatus]"
ENSG00000257923(CUX1)	--	27.85771058	3192	25.63980532	3135	24.44624913	2840	22.54875615	2437	26.6465306	2756	24.97503666	2874	0.728876149	-0.419954509	normal	0.97649243	-0.207209417	normal	0.989847304	0.008872993	normal	0.255166606	-0.205272448	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09313|0|hsa:1523|CUX1, CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75; cut-like homeobox 1; K09313 homeobox protein cut-like (A)"	--	[K]	Transcription	CUT domain;; Homeobox domain;; Homeobox KN domain	Homeobox protein cut-like 1 GN=CUX1 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: homeobox protein cut-like 1 [Orcinus orca]
ENSG00000258102(MAP1LC3B2)	--	0.241381	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: autophagic vacuole assembly (GO:0000045);; Cellular Component: cytoplasm (GO:0005737);; 	--	--	[Z]	Cytoskeleton	Autophagy protein Atg8 ubiquitin like;; Ubiquitin-like autophagy protein Apg12	Microtubule-associated proteins 1A/1B light chain 3 beta 2 (Precursor) GN=MAP1LC3B2 OS=Homo sapiens (Human) PE=2 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: microtubule-associated proteins 1A/1B light chain 3B [Myotis davidii] 
ENSG00000258130(RP11-347C12.3)	--	1.258717	40	1.298122148	42	1.512405	48	1.3717832	44	0.821180153	26	1.803002004	57	0.980468003	0.102901955	normal	0.915946979	-0.681812132	normal	0.971571837	0.232895345	normal	0.965475915	-0.053938138	normal	--	--	--	--	--	[R]	General function prediction only	--	SAGA-associated factor 29 homolog GN=CCDC101 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SAGA-associated factor 29 homolog [Ceratotherium simum simum]
ENSG00000258150(RP11-345J4.3)	--	0	0	0	0	0	0	0	0	0	0	0.033564634	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	SAGA-associated factor 29 homolog GN=CCDC101 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: SAGA-associated factor 29 homolog [Ceratotherium simum simum]
ENSG00000258227(CLEC5A)	--	0	0	0	0	0	0	0.0168204	1	0	0	0.016903749	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	K10073|1.10386e-124|ggo:101153257|CLEC5A; C-type lectin domain family 5 member A; K10073 C-type lectin domain family 5 member A (A)	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 5 member A GN=CLEC5A OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: C-type lectin domain family 5 member A isoform 1 [Ceratotherium simum simum]
ENSG00000258366(RTEL1)	--	3.034369123	309	2.8706494	282	3.889198853	339	3.135391778	254	3.7904664	303	2.932415125	274	0.891539399	-0.311896796	normal	0.963768222	0.081772971	normal	0.887444638	-0.31384047	normal	0.553656808	-0.18300672	normal	[KL]	"Transcription;; Replication, recombination and repair"	"Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP-dependent DNA helicase activity (GO:0004003);; Molecular Function: ATP binding (GO:0005524);; Biological Process: nucleobase-containing compound metabolic process (GO:0006139);; Molecular Function: ATP-dependent helicase activity (GO:0008026);; Molecular Function: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides (GO:0016818);; "	"K11136|0|hsa:51750|RTEL1, C20orf41, DKCA4, DKCB5, NHL, RTEL; regulator of telomere elongation helicase 1 (EC:3.6.4.12); K11136 regulator of telomere elongation helicase 1 [EC:3.6.4.12] (A)"	--	[L]	"Replication, recombination and repair"	"Helicase C-terminal domain;; DEAD_2;; Type III restriction enzyme, res subunit;; DEAD/DEAH box helicase"	Regulator of telomere elongation helicase 1 {ECO:0000255|HAMAP-Rule:MF_03065} OS=Homo sapiens (Human) PE=1 SV=2	L	"Replication, recombination and repair"	PREDICTED: LOW QUALITY PROTEIN: regulator of telomere elongation helicase 1 [Equus caballus]
ENSG00000258453(OR11H2)	--	0	0	0	0	0.212024	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 11H2 GN=OR11H2 OS=Homo sapiens (Human) PE=3 SV=1	T	Signal transduction mechanisms	"PREDICTED: olfactory receptor 11H12-like, partial [Tupaia chinensis]"
ENSG00000258890(CEP95)	--	9.0824185	399	7.296901	388	9.307143	436	10.284188	520	10.8427668	588	12.173671	615	0.832548557	0.35010681	normal	0.170848449	0.57649556	normal	0.441514369	0.486539169	normal	0.013936225	0.474029057	normal	--	--	--	"K16544|0|hsa:90799|CEP95, CCDC45; centrosomal protein 95kDa; K16544 centrosomal protein CEP95 (A)"	--	--	--	--	Centrosomal protein of 95 kDa GN=CEP95 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: centrosomal protein of 95 kDa [Ceratotherium simum simum]
ENSG00000258986(TMEM179)	--	0.256486647	8	0.0948837	3	0.0857719	2	0.0650133	2	0.1081842	2	0.246487313	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Transmembrane protein 179 GN=TMEM179 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: transmembrane protein 179 [Bos mutus] 
ENSG00000259120(SMIM6)	--	1.44466	17	1.25122	15	1.646269	20	5.574211	67	4.89513	57	3.9709	50	0.000252188	1.857296437	up	0.001792004	1.80503126	up	0.219685425	1.251877353	normal	0.000404496	1.720847737	up	--	--	--	--	--	--	--	--	Small integral membrane protein 6 GN=SMIM6 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 6 [Felis catus]
ENSG00000259207(ITGB3)	--	3.09020275	359	2.407105	264	2.518796002	270	7.912052	916	6.13112804	696	4.78386	538	3.56E-11	1.316879524	up	5.26E-11	1.372097684	up	2.70E-05	0.982381595	normal	0.001094944	1.244603437	up	--	--	--	"K06493|0|hsa:3690|ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); K06493 integrin beta 3 (A)"	Rap1 signaling pathway (ko04015);; Phagosome (ko04145);; PI3K-Akt signaling pathway (ko04151);; Osteoclast differentiation (ko04380);; Focal adhesion (ko04510);; ECM-receptor interaction (ko04512);; Platelet activation (ko04611);; Hematopoietic cell lineage (ko04640);; Regulation of actin cytoskeleton (ko04810);; Thyroid hormone signaling pathway (ko04919);; Proteoglycans in cancer (ko05205);; MicroRNAs in cancer (ko05206);; Hypertrophic cardiomyopathy (HCM) (ko05410);; Arrhythmogenic right ventricular cardiomyopathy (ARVC) (ko05412);; Dilated cardiomyopathy (ko05414)	[TW]	Signal transduction mechanisms;; Extracellular structures	"Integrin, beta chain;; Integrin beta cytoplasmic domain;; Integrin beta tail domain;; EGF-like domain"	Integrin beta-3 (Precursor) GN=ITGB3 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: integrin beta-3 [Physeter catodon]
ENSG00000259224(SLC35G6)	--	0.272873	8	0.163543	5	0.13002	3	0.0333191	1	0.234093	6	0.337362	10	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	EamA-like transporter family	Solute carrier family 35 member G6 GN=SLC35G6 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: solute carrier family 35 member G6 [Oryctolagus cuniculus]
ENSG00000259330(INAFM2)	--	2.72522	137	2.48362	129	2.3973	124	4.09997	209	3.13554	157	2.89773	147	0.482324904	0.573255525	normal	0.938969329	0.259208822	normal	0.948197294	0.234554414	normal	0.295405983	0.373019711	normal	--	--	--	--	--	--	--	TRP-interacting helix	Putative transmembrane protein INAFM2 {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: proline-rich protein 24-like [Pteropus alecto]
ENSG00000259417(LINC01314)	--	0.0641447	9	0.0142046	2	0.0564393	7	0	0	0.00693851	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cortexin of kidney	Cortexin-2 GN=CTXN2 OS=Homo sapiens (Human) PE=3 SV=1	--	--	PREDICTED: cortexin-2-like isoform X1 [Equus caballus] 
ENSG00000259431(THTPA)	--	11.306615	388	14.18825678	468	13.24084279	450	10.87432749	338	9.808217405	346	13.48605571	450	0.935858814	-0.228893556	normal	0.601185374	-0.455444352	normal	0.970796774	-0.008263671	normal	0.376138392	-0.224025059	normal	--	--	--	"K05307|2.52184e-136|hsa:79178|THTPA, THTP, THTPASE; thiamine triphosphatase (EC:3.6.1.28); K05307 thiamine-triphosphatase [EC:3.6.1.28] (A)"	Thiamine metabolism (ko00730)	--	--	CYTH domain	Thiamine-triphosphatase GN=THTPA OS=Homo sapiens (Human) PE=1 SV=3	H	Coenzyme transport and metabolism	PREDICTED: thiamine-triphosphatase [Camelus dromedarius]
ENSG00000259494(MRPL46)	--	22.811077	453	20.75535	408	22.250736	447	22.48353	449	25.74184	504	23.37619	460	0.969896282	-0.043479742	normal	0.906376281	0.282484472	normal	0.970417058	0.03295767	normal	0.773040981	0.090427409	normal	--	--	--	"K17427|0|hsa:26589|MRPL46, C15orf4, LIECG2, P2ECSL; mitochondrial ribosomal protein L46; K17427 large subunit ribosomal protein L46 (A)"	--	[J]	"Translation, ribosomal structure and biogenesis"	39S mitochondrial ribosomal protein L46	"39S ribosomal protein L46, mitochondrial (Precursor) GN=MRPL46 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L46, mitochondrial [Sus scrofa] "
ENSG00000259511(UBE2Q2L)	--	1.62665	8	1.55804	8	0.378035	1	1.51885	8	1.76935	8	0.976739	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative ubiquitin-conjugating enzyme E2Q2-like protein GN=UBE2Q2L OS=Homo sapiens (Human) PE=5 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin-conjugating enzyme E2 Q2-like [Bos mutus]
ENSG00000259571(BLID)	--	0	0	0.263111	3	0.173401	1	0.0868464	1	0	0	0.262882	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	BH3-like motif-containing cell death inducer GN=BLID OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: BH3-like motif-containing cell death inducer [Ceratotherium simum simum]
ENSG00000259803(SLC22A31)	--	1.115582575	29	0.26410691	7	0.613220063	16	0.038453771	1	0.190422545	4	0	0	0.000105357	-3.610382629	down	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transmembrane transporter activity (GO:0022857);; Biological Process: transmembrane transport (GO:0055085);; 	--	--	[R]	General function prediction only	Sugar (and other) transporter;; Major Facilitator Superfamily	Putative solute carrier family 22 member 31 GN=SLC22A31 OS=Homo sapiens (Human) PE=3 SV=3	R	General function prediction only	PREDICTED: putative solute carrier family 22 member 31 [Myotis lucifugus]
ENSG00000259956(RBM15B)	--	10.4928	1345	10.5082	1363	9.40952	1220	13.1121	1682	13.8342	1770	12.0249	1548	0.923050737	0.291441063	normal	0.852211875	0.355190546	normal	0.872946629	0.334863556	normal	0.04266769	0.326563178	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	K13190|0|ptr:460403|RBM15B; RNA binding motif protein 15B; K13190 RNA-binding protein 15 (A)	--	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; SPOC domain;; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	Putative RNA-binding protein 15B GN=RBM15B OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	PREDICTED: putative RNA-binding protein 15B [Lipotes vexillifer]
ENSG00000260001(TGFBR3L)	--	0.598997	8	0.290446	4	0.765786	10	1.5494	21	1.56468	21	1.38431	19	0.910248624	1.213437628	normal	0.385962273	2.012224139	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	Zona pellucida-like domain	Transforming growth factor-beta receptor type 3-like protein GN=TGFBR3L OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: transforming growth factor-beta receptor type 3-like protein [Dasypus novemcinctus]
ENSG00000260027(HOXB7)	--	12.0399	291	11.8177	291	12.1915	301	17.6285	432	19.1385	466	19.62	483	0.333480089	0.536840189	normal	0.065756724	0.655170533	normal	0.041845659	0.671281731	normal	0.001927603	0.624451879	normal	--	--	Molecular Function: DNA binding (GO:0003677);; 	"K09307|3.39669e-132|hsa:3217|HOXB7, HHO.C1, HOX2, HOX2C, Hox-2.3; homeobox B7; K09307 homeobox protein HoxA/B7 (A)"	--	[R]	General function prediction only	Homeobox domain	Homeobox protein Hox-B7 GN=HOXB7 OS=Homo sapiens (Human) PE=1 SV=4	K	Transcription	homeobox protein Hox-B7 [Bos taurus] 
ENSG00000260097(SPDYE6)	--	0.115218	4	0.0281646	1	0.110829	3	0.0566844	2	0.0280024	0	0.0567166	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cell cycle regulatory protein	Putative speedy protein E6 GN=SPDYE6 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: speedy protein E4-like [Ursus maritimus]
ENSG00000260220(CCDC187)	--	0	0	0	0	0.027314243	3	0.014749898	2	0.014081118	0	0.042908583	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC103566745 [Equus przewalskii]
ENSG00000260230(FRRS1L)	--	0	0	0	0	0	0	0.173967	22	0.347803	43	0.214012	27	0.001475622	3.922870012	up	4.01E-09	4.869087281	up	5.10E-05	4.232858564	up	9.08E-10	Inf	up	--	--	--	--	--	[T]	Signal transduction mechanisms	DOMON domain	DOMON domain-containing protein FRRS1L GN=FRRS1L OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: DOMON domain-containing protein FRRS1L [Ochotona princeps]
ENSG00000260325(HSPB9)	--	0.156587	5	0.21181	7	0.119515	3	0.123827	4	0.213177	6	0.0928603	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K09547|7.32901e-114|hsa:94086|HSPB9, CT51; heat shock protein, alpha-crystallin-related, B9; K09547 heat shock protein beta-9 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Hsp20/alpha crystallin family	Heat shock protein beta-9 GN=HSPB9 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: heat shock protein beta-9 [Oryctolagus cuniculus]
ENSG00000260596(DUX4)	--	4.416758551	91	3.760376009	86	6.150424419	123	3.303912719	68	4.13070102	82	4.354204954	98	0.907819877	-0.442487882	normal	0.969810825	-0.088544542	normal	0.928270275	-0.331519625	normal	0.553119185	-0.294076484	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	--	--	[K]	Transcription	Homeobox domain;; Homeobox KN domain	Double homeobox protein 4 {ECO:0000312|HGNC:HGNC:50800} OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: double homeobox protein 1-like [Galeopterus variegatus] 
ENSG00000260691(ANKRD20A1)	--	0.095133929	7	0.075879188	5	0.060686301	3	0.091050311	6	0.074060191	4	0.060766754	4	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K17299|0|hsa:84210|ANKRD20A1, ANKRD20A; ankyrin repeat domain 20 family, member A1; K17299 POTE ankyrin domain family protein (A)"	--	[R]	General function prediction only	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 20A1 GN=ANKRD20A1 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like isoform X4 [Bos taurus]
ENSG00000261052(SULT1A3)	--	0.0803208	2	0.071424702	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: sulfotransferase activity (GO:0008146);; 	"K01014|0|hsa:445329|SULT1A4, HAST3, M-PST, ST1A3/ST1A4, ST1A4, TL-PST; sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 (EC:2.8.2.1); K01014 aryl sulfotransferase [EC:2.8.2.1] (A)"	Chemical carcinogenesis (ko05204)	[R]	General function prediction only	Sulfotransferase domain	Sulfotransferase 1A4 GN=SULT1A4 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: sulfotransferase 1A1 isoform X1 [Equus caballus] 
ENSG00000261115(TMEM178B)	--	5.112465379	651	5.151193607	764	5.264822682	693	0.314155929	40	0.37019516	39	0.29675982	36	0	-4.003833536	down	0	-4.260999531	down	0	-4.218680325	down	5.83E-89	-4.217730237	down	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	PMP-22/EMP/MP20/Claudin tight junction	Transmembrane protein 178B (Precursor) GN=TMEM178B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 178B [Bos taurus] 
ENSG00000261150(EPPK1)	--	0.04970256	16	0.027327772	9	0.041161973	13	0.111180625	36	0.068868124	22	0.024801559	8	0.765271804	1.069084067	normal	0.909292967	1.1421424	normal	--	--	--	--	--	--	--	--	Cellular Component: cytoskeleton (GO:0005856);; 	--	--	[Z]	Cytoskeleton	Plectin repeat;; HTH DNA binding domain;; Uncharacterized protein conserved in bacteria (DUF2094)	Epiplakin GN=EPPK1 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: epiplakin [Galeopterus variegatus]
ENSG00000261210(CLEC19A)	--	0	0	0	0	0.390464	1	0	0	0	0	0.393229	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[TV]	Signal transduction mechanisms;; Defense mechanisms	Lectin C-type domain	C-type lectin domain family 19 member A (Precursor) GN=CLEC19A OS=Homo sapiens (Human) PE=2 SV=1	TV	Signal transduction mechanisms;; Defense mechanisms	PREDICTED: C-type lectin domain family 19 member A-like [Physeter catodon]
ENSG00000261221(ZNF865)	--	15.264543	1280	13.636682	1181	14.5639542	1276	14.5663024	1286	15.009502	1394	15.52134386	1406	0.982179516	-0.024056623	normal	0.957911234	0.217538405	normal	0.976353045	0.131528269	normal	0.630537433	0.107992844	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Zinc finger protein 865 GN=ZNF865 OS=Homo sapiens (Human) PE=3 SV=1	K	Transcription	PREDICTED: zinc finger protein 865 [Orcinus orca]
ENSG00000261236(BOP1)	--	50.647974	2297	47.0504	2205	54.758489	2588	50.3521	2306	48.83695	2176	32.2048	1473	0.987977003	-0.025173802	normal	0.986962629	-0.040498697	normal	0.000141491	-0.820727328	normal	0.325603616	-0.273816221	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; Biological Process: rRNA processing (GO:0006364);; 	K14824|0|hsa:23246|BOP1; block of proliferation 1; K14824 ribosome biogenesis protein ERB1 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	"BOP1NT (NUC169) domain;; WD domain, G-beta repeat"	Ribosome biogenesis protein BOP1 {ECO:0000255|HAMAP-Rule:MF_03027} OS=Homo sapiens (Human) PE=1 SV=2	J	"Translation, ribosomal structure and biogenesis"	PREDICTED: ribosome biogenesis protein BOP1 [Eptesicus fuscus]
ENSG00000261247(GOLGA8T)	--	0.527253	26	0.199739	10	0.569516	28	0.38284	19	0.157439	7	0.401863	20	0.979914805	-0.451974197	normal	--	--	--	0.977076875	-0.463942367	normal	0.637984073	-0.496832448	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8J GN=GOLGA8J OS=Homo sapiens (Human) PE=3 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000261308(FIGNL2)	--	0.476002889	37	0.591350752	46	0.579034	46	0.380418742	29	0.349322713	27	0.32330099	25	0.97481213	-0.36513309	normal	0.864736198	-0.757234241	normal	0.809752116	-0.849562513	normal	0.249698436	-0.692871201	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: ATP binding (GO:0005524);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	ATPase family associated with various cellular activities (AAA)	Putative fidgetin-like protein 2 GN=FIGNL2 OS=Homo sapiens (Human) PE=5 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"PREDICTED: putative fidgetin-like protein 2-like, partial [Lipotes vexillifer]"
ENSG00000261371(PECAM1)	--	0	0	0	0	0	0	0.00685834	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06471|0|hsa:5175|PECAM1, CD31, CD31/EndoCAM, GPIIA', PECA1, PECAM-1, endoCAM; platelet/endothelial cell adhesion molecule 1; K06471 platelet/endothelial cell adhesion molecule (A)"	Cell adhesion molecules (CAMs) (ko04514);; Leukocyte transendothelial migration (ko04670);; Malaria (ko05144)	--	--	Immunoglobulin domain;; Immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain;; Immunoglobulin V-set domain	Platelet endothelial cell adhesion molecule (Precursor) GN=PECAM1 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: platelet endothelial cell adhesion molecule isoform X1 [Tupaia chinensis]
ENSG00000261456(TUBB8)	--	0.125219682	6	0.094121265	5	0.029141022	0	0.042662515	2	0	0	0.058641417	3	--	--	--	--	--	--	--	--	--	--	--	--	[Z]	Cytoskeleton	Molecular Function: GTPase activity (GO:0003924);; 	"K07375|0|hsa:347688|TUBB8, bA631M21.2; tubulin, beta 8 class VIII; K07375 tubulin beta (A)"	Phagosome (ko04145);; Gap junction (ko04540);; Pathogenic Escherichia coli infection (ko05130)	[Z]	Cytoskeleton	"Tubulin/FtsZ family, GTPase domain;; Tubulin C-terminal domain;; Misato Segment II tubulin-like domain"	Tubulin beta-8 chain GN=TUBB8 OS=Homo sapiens (Human) PE=1 SV=2	Z	Cytoskeleton	PREDICTED: tubulin beta-4B chain isoform X1 [Orycteropus afer afer]
ENSG00000261587(TMEM249)	--	0.264182	3	0.130511	1	0.330289	3	0.513244	6	0.25651385	2	0.258125	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4579)	Transmembrane protein 249 GN=TMEM249 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: transmembrane protein 249 [Tupaia chinensis]
ENSG00000261594(TPBGL)	--	0.123365	5	0.344723	14	0.165562	6	0.074279	3	0.118583	4	0.0242034	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	Leucine rich repeat;; Leucine Rich repeats (2 copies)	Trophoblast glycoprotein-like (Precursor) GN=TPBGL OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: trophoblast glycoprotein-like [Mustela putorius furo]
ENSG00000261609(GAN)	--	1.6489	406	1.64574	407	1.68568	410	1.764	438	1.725	425	1.39175	343	0.967309486	0.078333447	normal	0.968505306	0.040858918	normal	0.918802677	-0.264638078	normal	0.911558094	-0.04204374	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	K10453|0|pon:100453030|GAN; gigaxonin; K10453 kelch-like protein 16 (gigaxonin) (A)	--	[TR]	Signal transduction mechanisms;; General function prediction only	"Kelch motif;; BTB And C-terminal Kelch;; Kelch motif;; BTB/POZ domain;; Galactose oxidase, central domain;; Galactose oxidase, central domain;; Kelch motif;; Kelch motif"	Gigaxonin GN=GAN OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: gigaxonin [Oryctolagus cuniculus]
ENSG00000261649(GOLGA6L7P)	--	0.0136552	1	0.012856	1	0	0	0	0	0.0133712	0	0.0135739	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	--	Golgin subfamily A member 6-like protein 2 GN=GOLGA6L2 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: golgin subfamily A member 2-like [Oryctolagus cuniculus]
ENSG00000261652(C15orf65)	--	4.49032	40	6.21425	54	4.34541	38	2.83813	26	3.8938	35	3.71014	34	0.941434524	-0.622436825	normal	0.895700265	-0.625116076	normal	0.980985483	-0.1619393	normal	0.445106796	-0.495305598	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4490)	Uncharacterized protein C15orf65 GN=C15orf65 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C15orf65 homolog isoform X1 [Felis catus] 
ENSG00000261678(SCRT1)	--	0.0324123	2	0	0	0.0154269	0	0	0	0	0	0.0157911	1	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	K09219|7.33343e-98|ngi:103735254|Scrt1; scratch family zinc finger 1; K09219 scratch (A)	--	[K]	Transcription	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc-finger of C2H2 type"	Transcriptional repressor scratch 1 GN=SCRT1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: transcriptional repressor scratch 1 [Erinaceus europaeus]
ENSG00000261701(HPR)	--	0	0	0	0	0.0562561	0	0.0563836	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: serine-type endopeptidase activity (GO:0004252);; Biological Process: proteolysis (GO:0006508);; 	"K14477|0|hsa:3250|HPR, A-259H10.2, HP; haptoglobin-related protein; K14477 haptoglobin-related protein (A)"	African trypanosomiasis (ko05143)	[E]	Amino acid transport and metabolism	Trypsin	Haptoglobin-related protein (Precursor) GN=HPR OS=Homo sapiens (Human) PE=1 SV=2	E	Amino acid transport and metabolism	haptoglobin precursor [Oryctolagus cuniculus] 
ENSG00000261739(GOLGA8S)	--	0.0437892	2	0	0	0.0630102	2	0.0649134	3	0.0850368	3	0.130014	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8M OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000261787(TCF24)	--	0.0895931	3	0.088694	3	0.175179	5	0.147191	5	0.200012	6	0.352569	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein dimerization activity (GO:0046983);; 	--	--	[K]	Transcription	Helix-loop-helix DNA-binding domain	Transcription factor 24 GN=TCF24 OS=Homo sapiens (Human) PE=3 SV=3	K	Transcription	PREDICTED: transcription factor 24 [Sus scrofa]
ENSG00000261794(GOLGA8H)	--	1.296580205	101	1.040179741	82	1.305602441	102	1.136411324	90	1.308708186	102	1.094679504	86	0.962359789	-0.194061071	normal	0.946816525	0.288665599	normal	0.954986321	-0.250403761	normal	0.940739805	-0.056878511	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Golgin subfamily A member 8H GN=GOLGA8H OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000261857(MIA)	--	0.209583	10	1.092912	27	0.286745	13	0.271964	13	1.292289045	17	1.005806433	34	--	--	--	0.964827958	-0.643083868	normal	0.574138069	1.283360457	normal	--	--	--	--	--	--	K16655|1.24301e-91|ptr:456048|MIA; melanoma inhibitory activity; K16655 melanoma inhibitory activity protein (A)	--	--	--	Variant SH3 domain	Melanoma-derived growth regulatory protein (Precursor) GN=MIA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: melanoma-derived growth regulatory protein isoform X2 [Felis catus] 
ENSG00000262165(RP11-81A22.5)	--	0.926445	2	0	0	0.407935	0	0	0	0	0	0.434435	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: collagen alpha-1(II) chain-like [Loxodonta africana]
ENSG00000262180(OCLM)	--	0.382155	3	0.888823	7	0.638197	4	1.00728	8	0.865379	6	0.882977	7	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Oculomedin GN=OCLM OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	--
ENSG00000262484(CCER2)	--	0.586234483	13	0.280802758	7	0.4531986	10	0.260502	6	0.3321668	6	0.74955	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Coiled-coil domain-containing glutamate-rich protein 2 (Precursor) GN=CCER2 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: uncharacterized protein LOC101407297 [Ceratotherium simum simum]
ENSG00000262621(LA16c-306E5.2)	--	0.478036	21	0.49741	22	0.426993	18	0.409389	18	0.753628	33	0.768041	34	0.987917896	-0.234660661	normal	0.965386526	0.533427165	normal	0.902027773	0.856141775	normal	0.568862345	0.458997947	normal	[R]	General function prediction only	--	"K09228|5.6684e-74|hsa:54925|ZSCAN32, HCCS-5, ZNF434; zinc finger and SCAN domain containing 32; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	--	Zinc finger and SCAN domain-containing protein 32 GN=ZSCAN32 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein with KRAB and SCAN domains 1-like [Condylura cristata]
ENSG00000262655(SPON1)	--	0.0599249	6	0.0397898	4	0.0491184	4	0.140353	14	0.097105	9	0.0198788	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[W]	Extracellular structures	Thrombospondin type 1 domain;; Spondin_N;; Reeler domain	Spondin-1 (Precursor) GN=SPON1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: spondin-1 [Camelus bactrianus]
ENSG00000262919(FAM58A)	--	18.85716395	363	18.897319	368	17.2280548	335	21.502452	417	21.210269	394	18.44602342	361	0.954190021	0.168579483	normal	0.965793423	0.076758426	normal	0.964201964	0.099115195	normal	0.71789798	0.114992319	normal	[DKL]	"Cell cycle control, cell division, chromosome partitioning;; Transcription;; Replication, recombination and repair"	--	--	--	[D]	"Cell cycle control, cell division, chromosome partitioning"	"Cyclin, N-terminal domain"	Cyclin-related protein FAM58A GN=FAM58A OS=Homo sapiens (Human) PE=1 SV=2	D	"Cell cycle control, cell division, chromosome partitioning"	PREDICTED: cyclin-related protein FAM58A isoform X1 [Camelus bactrianus]
ENSG00000263001(GTF2I)	--	85.97667	6775	94.841412	7309	91.206822	7096	104.936613	7676	115.484946	8314	105.53627	7882	0.992212049	0.149269686	normal	0.991735641	0.164410245	normal	0.99266736	0.143235322	normal	0.485739364	0.151542655	normal	--	--	--	K03121|0|ptr:450163|GTF2I; general transcription factor IIi; K03121 transcription initiation factor TFII-I (A)	Basal transcription factors (ko03022);; cGMP-PKG signaling pathway (ko04022);; Herpes simplex infection (ko05168)	--	--	GTF2I-like repeat	General transcription factor II-I GN=GTF2I OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: general transcription factor II-I isoform X1 [Tupaia chinensis]
ENSG00000263002(ZNF234)	--	3.166040174	261	3.943456512	313	3.608848093	292	2.81549663	244	3.005470063	238	3.388227779	284	0.959977972	-0.127226097	normal	0.761151233	-0.41432411	normal	0.966707733	-0.048116188	normal	0.530741125	-0.197786083	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:10780|ZNF234, HZF4, ZNF269; zinc finger protein 234; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; C2H2-type zinc finger;; KRAB box;; Zinc-finger of C2H2 type;; Phorbol esters/diacylglycerol binding domain (C1 domain);; Zinc ribbon domain"	Zinc finger protein 234 GN=ZNF234 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 234 [Galeopterus variegatus]
ENSG00000263465(SRSF8)	--	4.8289	310	4.69647	304	4.29766	275	5.25782	341	6.41369	412	6.03931	390	0.963007424	0.106169448	normal	0.728278412	0.415365443	normal	0.505973588	0.493461239	normal	0.162233907	0.341650158	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; 	"K12891|6.97847e-63|mcf:102145084|SRSF8; serine/arginine-rich splicing factor 8; K12891 splicing factor, arginine/serine-rich 2 (A)"	Spliceosome (ko03040);; Herpes simplex infection (ko05168)	[A]	RNA processing and modification	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Serine/arginine-rich splicing factor 8 GN=SRSF8 OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: serine/arginine-rich splicing factor 2 [Ornithorhynchus anatinus] 
ENSG00000263513(FAM72C)	--	2.008773	73	1.03694	38	2.63815	95	2.03768	75	1.361330009	50	1.123306	41	0.974330085	0.007995843	normal	0.964034849	0.361913224	normal	0.012519236	-1.190911733	normal	0.699348942	-0.333459542	normal	--	--	--	--	--	--	--	FAM72 protein	Protein FAM72C GN=FAM72C OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	PREDICTED: protein FAM72A [Canis lupus familiaris]
ENSG00000263528(IKBKE)	--	6.42664469	304	5.810201168	350	7.672192428	301	6.82553672	387	8.586279243	423	10.34980162	522	0.881626414	0.316011638	normal	0.925486165	0.250888887	normal	0.003770024	0.782970913	normal	0.036460608	0.459553849	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K07211|0|pps:100992569|IKBKE; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon; K07211 inhibitor of nuclear factor kappa-B kinase subunit epsilon [EC:2.7.11.10] (A)"	Toll-like receptor signaling pathway (ko04620);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; Measles (ko05162);; Influenza A (ko05164);; Herpes simplex infection (ko05168)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	Inhibitor of nuclear factor kappa-B kinase subunit epsilon GN=IKBKE OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1 [Tursiops truncatus]
ENSG00000263874(LINC00672)	--	0.723070156	46	0.512239	30	0.481551029	30	0.765006	48	0.4200802	26	0.60666934	39	0.979851363	0.029600431	normal	0.982365449	-0.216161955	normal	0.973799592	0.354507326	normal	0.955665903	0.069802186	normal	--	--	--	--	--	--	--	--	--	--	--	F-box only protein 47 [Myotis brandtii]
ENSG00000263956(NBPF11)	--	2.591709818	325	2.348925357	289	2.657074917	310	1.970578931	246	2.761731001	320	3.18142652	374	0.719047018	-0.430267065	normal	0.959568539	0.12495429	normal	0.921335008	0.261316424	normal	0.999834061	0.004888846	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220)	Neuroblastoma breakpoint family member 11 GN=NBPF11 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4 [Bos taurus] 
ENSG00000263961(C1orf186)	--	0.033153	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C1orf186 GN=C1orf186 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C1orf186 homolog [Ceratotherium simum simum]
ENSG00000264230(ANXA8L1)	--	5.266198873	244	3.884141236	177	5.131471486	246	24.46671085	1039	24.46752605	1014	15.88070078	724	0	2.052605223	up	0	2.486792547	up	2.78E-14	1.543242426	up	1.06E-12	2.035964115	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	K17096|0|mcc:694628|ANXA8; annexin A8; K17096 annexin A8 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A8-like protein 2 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A8-like isoform 2 [Ovis aries]
ENSG00000264343(NOTCH2NL)	--	2.781236242	135	3.396581047	167	4.04981105	161	5.179392095	255	3.3857165	167	4.059359143	190	0.006204303	0.879311079	normal	0.96600013	-0.021234272	normal	0.943920245	0.228668027	normal	0.238425027	0.380297927	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	[T]	Signal transduction mechanisms	EGF-like domain;; Human growth factor-like EGF;; EGF-like domain;; Calcium-binding EGF domain	Notch homolog 2 N-terminal-like protein GN=NOTCH2NL OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: neurogenic locus notch homolog protein 2 [Tupaia chinensis]
ENSG00000264364(DYNLL2)	--	20.31101	2836	17.3948	2437	18.09068	2474	22.82137	3146	21.45974	2923	18.947	2697	0.986978032	0.118767768	normal	0.96657691	0.240780434	normal	0.985707776	0.11615056	normal	0.423107209	0.156546848	normal	--	--	--	"K10418|1.92137e-61|fca:101098906|DYNLL2; dynein, light chain, LC8-type 2; K10418 dynein light chain LC8-type (A)"	Vasopressin-regulated water reabsorption (ko04962)	[Z]	Cytoskeleton	Dynein light chain type 1	"Dynein light chain 2, cytoplasmic GN=DYNLL2 OS=Homo sapiens (Human) PE=1 SV=1"	Z	Cytoskeleton	"PREDICTED: dynein light chain 2, cytoplasmic isoform 1 [Odobenus rosmarus divergens]"
ENSG00000264522(OTUD7B)	--	6.8703364	757	6.913473	808	6.065641606	770	6.471313808	767	6.505771889	834	6.879226497	841	0.976319679	-0.011875042	normal	0.976501881	0.024220913	normal	0.970802907	0.118732719	normal	0.886763815	0.043709676	normal	--	--	Molecular Function: DNA binding (GO:0003677);; Molecular Function: zinc ion binding (GO:0008270);; 	"K11860|0|hsa:56957|OTUD7B, CEZANNE, ZA20D1; OTU deubiquitinase 7B (EC:3.4.19.12); K11860 OTU domain-containing protein 7 [EC:3.4.19.12] (A)"	--	[T]	Signal transduction mechanisms	OTU-like cysteine protease;; UBA-like domain	OTU domain-containing protein 7B GN=OTUD7B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: OTU domain-containing protein 7B [Ceratotherium simum simum]
ENSG00000264717(CH17-360D5.1)	--	0.382352339	12	0.220877826	7	0.529159118	16	4.889790827	155	5.04362955	158	5.348318241	170	0	3.502644251	up	0	4.208555992	up	0	3.283975569	up	1.47E-23	3.766769963	up	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	K04206|0|hsa:100996758|neuropeptide Y receptor type 4-like; K04206 neuropeptide Y receptor type 4 (A)	Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx	Neuropeptide Y receptor type 4 GN=NPY4R OS=Homo sapiens (Human) PE=2 SV=1	T	Signal transduction mechanisms	PREDICTED: neuropeptide Y receptor type 4 [Orcinus orca] 
ENSG00000265190(ANXA8)	--	7.1673134	243	7.127018393	241	8.120933372	277	23.72933699	868	21.92753725	803	20.7807988	754	0	1.799488691	up	0	1.708716985	up	1.54E-12	1.431453605	up	6.30E-24	1.650644505	up	--	--	Molecular Function: calcium ion binding (GO:0005509);; Molecular Function: calcium-dependent phospholipid binding (GO:0005544);; 	K17096|0|mcc:694628|ANXA8; annexin A8; K17096 annexin A8 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Annexin	Annexin A8 GN=ANXA8 OS=Homo sapiens (Human) PE=1 SV=3	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: annexin A8-like isoform 2 [Ovis aries]
ENSG00000265203(RBP3)	--	0.0113267	1	0.0222368	2	0	0	0.0569193	5	0.0330458	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Biological Process: proteolysis (GO:0006508);; Molecular Function: serine-type peptidase activity (GO:0008236);; 	--	--	--	--	Peptidase family S41;; Domain of unknown function (DUF3436)	Retinol-binding protein 3 (Precursor) GN=RBP3 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: retinol-binding protein 3 [Galeopterus variegatus]
ENSG00000265241(RBM8A)	--	41.96610463	1522	38.14791224	1565	42.6297	1525	58.795655	2344	55.7769	2359	45.14971472	1796	0.07020745	0.591687276	normal	0.126855041	0.570134554	normal	0.96013529	0.227478583	normal	0.005558839	0.47290655	normal	[R]	General function prediction only	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: RNA binding (GO:0003723);; 	K12876|3.76722e-96|umr:103678408|RBM8A; RNA binding motif protein 8A; K12876 RNA-binding protein 8A (A)	RNA transport (ko03013);; mRNA surveillance pathway (ko03015);; Spliceosome (ko03040)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA binding motif"	RNA-binding protein 8A GN=RBM8A OS=Homo sapiens (Human) PE=1 SV=1	A	RNA processing and modification	PREDICTED: RNA-binding protein 8A-like isoform X1 [Elephantulus edwardii]
ENSG00000265354(TIMM23)	--	68.4588	1309	65.2987	1292	66.5192	1295	65.1294	1269	67.9437	1291	57.9305	1113	0.980450675	-0.075515262	normal	0.981865424	-0.022517261	normal	0.953353644	-0.226504338	normal	0.637294429	-0.106572897	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	--	K17794|7.47105e-111|ptg:102956753|mitochondrial import inner membrane translocase subunit Tim23-like; K17794 mitochondrial import inner membrane translocase subunit TIM23 (A)	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Tim17/Tim22/Tim23/Pmp24 family	Mitochondrial import inner membrane translocase subunit Tim23 GN=TIMM23 OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: mitochondrial import inner membrane translocase subunit Tim23-like [Panthera tigris altaica]
ENSG00000265491(RNF115)	--	4.380721911	691	5.324070079	843	4.911052161	765	4.663202049	740	4.242452819	666	6.184771692	976	0.973668392	0.067861479	normal	0.81492519	-0.360707121	normal	0.844804551	0.342529069	normal	0.95372092	0.030723704	normal	--	--	Molecular Function: zinc ion binding (GO:0008270);; Molecular Function: metal ion binding (GO:0046872);; 	"K11982|0|hsa:27246|RNF115, BCA2, ZNF364; ring finger protein 115; K11982 E3 ubiquitin-protein ligase RNF115/126 [EC:6.3.2.19] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; RING-H2 zinc finger;; Zinc finger, C3HC4 type (RING finger);; zinc-finger;; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	E3 ubiquitin-protein ligase RNF115 {ECO:0000305} OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: E3 ubiquitin-protein ligase RNF115 [Ceratotherium simum simum]
ENSG00000265763(ZNF488)	--	4.601704656	306	3.398787598	226	5.747233697	383	5.838274	383	4.096098215	271	2.883622378	192	0.901875169	0.291669266	normal	0.933591276	0.23908092	normal	7.94E-05	-0.99884726	normal	0.857800023	-0.135657072	normal	--	--	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type"	Zinc finger protein 488 GN=ZNF488 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	"PREDICTED: zinc finger protein 488, partial [Camelus ferus]"
ENSG00000265808(SEC22B)	--	12.06507164	989	12.38753166	1070	11.07597271	936	13.01753104	1123	13.40142116	1150	13.19305051	1120	0.969847798	0.152261161	normal	0.977773002	0.082484043	normal	0.939061948	0.250256758	normal	0.443626693	0.158640669	normal	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Cellular Component: integral component of membrane (GO:0016021);; Biological Process: vesicle-mediated transport (GO:0016192);; 	K08517|1.41309e-143|tup:102496972|vesicle-trafficking protein SEC22b-like; K08517 vesicle transport protein SEC22 (A)	SNARE interactions in vesicular transport (ko04130);; Phagosome (ko04145);; Legionellosis (ko05134)	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Regulated-SNARE-like domain;; Synaptobrevin	Vesicle-trafficking protein SEC22b GN=SEC22B OS=Homo sapiens (Human) PE=1 SV=4	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: vesicle-trafficking protein SEC22b [Canis lupus familiaris] 
ENSG00000265972(TXNIP)	--	0.112848536	5	0.120209478	6	0.15169157	3	0.457871838	23	0.545971349	27	0.469913024	22	0.409828321	1.88210339	normal	0.190128747	1.905559034	normal	0.119769092	2.374849005	normal	0.000540738	2.340348168	up	--	--	--	--	--	[R]	General function prediction only	"Arrestin (or S-antigen), N-terminal domain;; Arrestin (or S-antigen), C-terminal domain"	Thioredoxin-interacting protein GN=TXNIP OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: thioredoxin-interacting protein [Ursus maritimus]
ENSG00000266028(SRGAP2)	--	14.58017472	1246	14.23173376	1164	16.152982	1348	14.50690689	1273	11.68887002	1146	12.93263588	1105	0.982165596	9.60E-05	normal	0.980095417	-0.043853151	normal	0.913499696	-0.294699771	normal	0.607892938	-0.11417295	normal	--	--	--	--	--	--	--	--	--	--	--	hypothetical protein D623_10018462 [Myotis brandtii]
ENSG00000266074(BAHCC1)-2	--	4.515847158	1049	3.78394744	894	4.050353956	971	4.149546416	960	5.1800278	1197	4.53728104	1065	0.968019377	-0.158497846	normal	0.735094171	0.399064618	normal	0.973292151	0.124833087	normal	0.580166073	0.124187792	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000266074(BAHCC1)-3	--	0.380432	11	0.238105	7	0.167908	4	0.552841	16	0.706955	20	0.307381	9	--	--	--	0.884358178	1.318772788	normal	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000266094(RASSF5)	--	1.144718207	73	0.748373365	51	1.27317943	82	1.025403135	68	1.443593221	95	0.419562192	29	0.972178309	-0.130350524	normal	0.293208792	0.857107412	normal	0.001834045	-1.460609014	down	0.910252232	-0.123635117	normal	--	--	Biological Process: signal transduction (GO:0007165);; Biological Process: intracellular signal transduction (GO:0035556);; 	"K08015|0|hsa:83593|RASSF5, Maxp1, NORE1, NORE1A, NORE1B, RAPL, RASSF3; Ras association (RalGDS/AF-6) domain family member 5; K08015 Ras association domain-containing protein 5 (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; Leukocyte transendothelial migration (ko04670);; Pathways in cancer (ko05200);; Non-small cell lung cancer (ko05223)	[T]	Signal transduction mechanisms	Ras association (RalGDS/AF-6) domain;; Phorbol esters/diacylglycerol binding domain (C1 domain)	Ras association domain-containing protein 5 GN=RASSF5 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: ras association domain-containing protein 5 isoform X1 [Elephantulus edwardii]
ENSG00000266173(STRADA)	--	15.94198222	635	17.17414903	608	17.52378477	592	14.96820695	565	17.96879586	651	14.21830588	594	0.950289116	-0.198827587	normal	0.970966054	0.076974616	normal	0.973626697	-0.003416973	normal	0.900643805	-0.040846144	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	K08271|0|pps:100970041|STRADA; STE20-related kinase adaptor alpha; K08271 STE20-related kinase adapter protein alpha (A)	mTOR signaling pathway (ko04150);; AMPK signaling pathway (ko04152)	[T]	Signal transduction mechanisms	Protein kinase domain;; Protein tyrosine kinase	STE20-related kinase adapter protein alpha GN=STRADA OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: STE20-related kinase adapter protein alpha isoform X1 [Camelus ferus] 
ENSG00000266265(KLF14)	--	0.0661477	3	0.0432408	2	0.0640517	2	0.0437964	2	0.0427462	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	"K09208|9.33876e-114|hsa:136259|KLF14, BTEB5; Kruppel-like factor 14; K09208 krueppel-like factor 9/13/14/16 (A)"	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 14 GN=KLF14 OS=Homo sapiens (Human) PE=2 SV=1	K	Transcription	PREDICTED: Krueppel-like factor 14 [Ceratotherium simum simum]
ENSG00000266338(NBPF15)	--	10.1755777	1462	9.186902558	1328	10.43184855	1488	9.456911856	1332	8.714849779	1258	8.865540894	1425	0.972152321	-0.164999733	normal	0.978524902	-0.099433423	normal	0.982164273	-0.070630689	normal	0.607456448	-0.112417115	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220)	Neuroblastoma breakpoint family member 15 GN=NBPF15 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4 [Bos taurus] 
ENSG00000266412(NCOA4)	--	46.80163709	2991	47.73627965	3040	45.12096257	2839	55.53295877	3541	59.0189262	3746	66.35990689	4230	0.977147629	0.212596213	normal	0.95786596	0.279727468	normal	0.138441969	0.566734459	normal	0.024071853	0.355994286	normal	--	--	--	"K09289|0|hsa:8031|NCOA4, ARA70, ELE1, PTC3, RFG; nuclear receptor coactivator 4; K09289 nuclear receptor coactivator 4 (A)"	Pathways in cancer (ko05200);; Thyroid cancer (ko05216)	--	--	Nuclear coactivator	Nuclear receptor coactivator 4 GN=NCOA4 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: nuclear receptor coactivator 4-like isoform 1 [Orcinus orca] 
ENSG00000266472(MRPS21)	--	44.4132	907	38.522	807	39.4523	823	48.6059	1006	47.4516	962	40.9013	843	0.973066223	0.118433042	normal	0.944663561	0.23164366	normal	0.977227145	0.026301006	normal	0.580166073	0.126216524	normal	--	--	--	K02970|4.93989e-46|ptr:746885|MRPS21; mitochondrial ribosomal protein S21; K02970 small subunit ribosomal protein S21 (A)	Ribosome (ko03010)	--	--	Ribosomal protein S21	"28S ribosomal protein S21, mitochondrial GN=MRPS21 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"28S ribosomal protein S21, mitochondrial [Bos taurus] "
ENSG00000266714(MYO15B)	--	6.2610148	453	8.466217081	556	7.001574293	567	26.5512194	2074	25.5059	1936	29.76819903	2566	0	2.160247557	up	0	1.775740812	up	0	2.16682977	up	4.28E-18	2.040528476	up	--	--	Molecular Function: motor activity (GO:0003774);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: cytoskeleton (GO:0005856);; Cellular Component: myosin complex (GO:0016459);; 	K10361|0|mcc:707287|MYO10; myosin-XV-like; K10361 myosin XV (A)	--	[N]	Cell motility	Myosin head (motor domain);; MyTH4 domain;; Variant SH3 domain;; FERM central domain	Unconventional myosin-XVB GN=MYO15B OS=Homo sapiens (Human) PE=1 SV=2	N	Cell motility	PREDICTED: putative unconventional myosin-XVB-like [Mustela putorius furo]
ENSG00000266733(TBC1D29)	--	0.032096798	2	0.015806878	1	0.046957015	2	0.048043392	3	0	0	0.015900634	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	Putative TBC1 domain family member 29 GN=TBC1D29 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: USP6 N-terminal-like protein [Oryctolagus cuniculus]
ENSG00000266964(FXYD1)	--	1.417220407	7	1.521710815	6	0.642417007	2	0.21225891	1	0.220711586	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	K13360|2.16471e-24|ptr:747770|FXYD1; phospholemman; K13360 FXYD domain-containing ion transport regulator 1 (A)	cAMP signaling pathway (ko04024)	--	--	ATP1G1/PLM/MAT8 family	Phospholemman (Precursor) GN=FXYD1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: phospholemman isoform X1 [Tupaia chinensis] 
ENSG00000267041(ZNF850)	--	1.291610263	124	1.9838531	113	0.94700517	123	0.565914	75	0.638622116	45	0.96601271	87	0.327058348	-0.744221346	normal	0.000773338	-1.320755353	down	0.815339754	-0.500508722	normal	0.025289137	-0.819192654	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:342892|ZNF850, ZNF850P; zinc finger protein 850; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; KRAB box;; Zinc-finger of C2H2 type;; Probable zinc-binding domain"	Zinc finger protein 850 GN=ZNF850 OS=Homo sapiens (Human) PE=3 SV=2	K	Transcription	PREDICTED: zinc finger protein 420 isoform X3 [Camelus dromedarius]
ENSG00000267221(CTD-2132N18.2)	--	0.934969	59	1.065691375	69	1.04881103	68	0.61720741	39	0.68282149	42	1.242426847	79	0.892163361	-0.608440734	normal	0.750521858	-0.717276271	normal	0.966530612	0.203817576	normal	0.605045806	-0.311757445	normal	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: uncharacterized protein LOC102899220 [Felis catus]
ENSG00000267368(UPK3BL)	--	26.2632	577	25.1331	550	26.0955	581	25.0444	550	24.3863	534	22.5402	503	0.968331024	-0.099699998	normal	0.970091191	-0.063840278	normal	0.943507501	-0.215667327	normal	0.632235429	-0.127389894	normal	--	--	--	--	--	--	--	--	Uroplakin-3b-like protein (Precursor) GN=UPK3BL OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: uroplakin-3b-like protein isoform X1 [Felis catus]
ENSG00000267680(ZNF224)	--	6.878511963	582	7.238921	564	7.355506	549	7.070187	578	8.279776	652	10.261652	759	0.9725659	-0.040674176	normal	0.953461586	0.187282872	normal	0.527379456	0.457924982	normal	0.345643291	0.210325647	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7767|ZNF224, BMZF-2, BMZF2, KOX22, ZNF255, ZNF27; zinc finger protein 224; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; C2H2-type zinc finger;; BolA-like protein"	Zinc finger protein 224 GN=ZNF224 OS=Homo sapiens (Human) PE=1 SV=3	K	Transcription	PREDICTED: zinc finger protein 234 [Camelus ferus]
ENSG00000267710(AC006116.20)	--	0	0	0	0	0	0	0.149922	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: uncharacterized protein LOC104974964 [Bos taurus] 
ENSG00000267795(SMIM22)	--	0	0	0.192908	1	0	0	0	0	0	0	0.180082	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Small integral membrane protein 22 GN=SMIM22 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 22 isoform X1 [Oryctolagus cuniculus] 
ENSG00000267796(LIN37)	--	8.630909813	188	8.347065287	186	9.166014413	206	8.488973633	192	8.649885791	131	10.02718484	218	0.967081072	-0.000454936	normal	0.654939249	-0.522076882	normal	0.964932904	0.072872264	normal	0.7820077	-0.12119453	normal	--	--	Biological Process: cell cycle (GO:0007049);; Cellular Component: transcriptional repressor complex (GO:0017053);; 	--	--	--	--	LIN37	Protein lin-37 homolog GN=LIN37 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: protein lin-37 homolog [Odobenus rosmarus divergens]
ENSG00000267855(NDUFA7)	--	52.0864	292	54.55457	307	49.5246	290	49.0904	298	52.64067	290	46.60021	263	0.967723112	-0.00148059	normal	0.961995245	-0.103089721	normal	0.957055616	-0.148468186	normal	0.824780737	-0.084637232	normal	--	--	Cellular Component: mitochondrial inner membrane (GO:0005743);; Molecular Function: NADH dehydrogenase (ubiquinone) activity (GO:0008137);; Biological Process: ATP synthesis coupled electron transport (GO:0042773);; 	"K03951|1.0579e-76|ptr:743262|NDUFA7; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa; K03951 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex subunit 7 (A)"	Oxidative phosphorylation (ko00190);; Non-alcoholic fatty liver disease (NAFLD) (ko04932);; Alzheimer's disease (ko05010);; Parkinson's disease (ko05012);; Huntington's disease (ko05016)	[C]	Energy production and conversion	NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a)	NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 GN=NDUFA7 OS=Homo sapiens (Human) PE=1 SV=3	C	Energy production and conversion	PREDICTED: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 [Balaenoptera acutorostrata scammoni]
ENSG00000267978(MAGEA9B)	--	0	0	0.399379125	4	0.02929741	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	MAGE family;; Melanoma associated antigen family N terminal	Melanoma-associated antigen 9 GN=MAGEA9B OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	"PREDICTED: melanoma-associated antigen 9-like, partial [Leptonychotes weddellii]"
ENSG00000268041(CTD-2575K13.6)	--	0.385786	14	0.434174	16	0.264125	9	0.304794	11	0.347994	12	0.244462	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	Ets-domain	ETS domain-containing transcription factor ERF GN=ERF OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: ETS domain-containing transcription factor ERF [Equus przewalskii]
ENSG00000268043(NBPF12)	--	2.57716221	397	2.395739843	369	2.384962599	341	2.128703339	309	2.432490902	366	2.76847962	411	0.776752184	-0.390645589	normal	0.967725235	-0.033067649	normal	0.921425388	0.260023408	normal	0.899311644	-0.048134508	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220);; Ribonuclease 2-5A	Neuroblastoma breakpoint family member 1 GN=NBPF1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4 [Bos taurus] 
ENSG00000268089(GABRQ)	--	0.284598	30	0.261514	28	0.17679	18	0.018834	2	0.0645198	6	0.0470109	5	0.000350975	-3.180034659	down	0.101484804	-1.992713645	normal	--	--	--	--	--	--	--	--	Molecular Function: extracellular ligand-gated ion channel activity (GO:0005230);; Biological Process: ion transport (GO:0006811);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05192|0|hsa:55879|GABRQ, THETA; gamma-aminobutyric acid (GABA) A receptor, theta; K05192 gamma-aminobutyric acid receptor subunit theta (A)"	Neuroactive ligand-receptor interaction (ko04080);; Retrograde endocannabinoid signaling (ko04723);; GABAergic synapse (ko04727);; Morphine addiction (ko05032);; Nicotine addiction (ko05033)	[T]	Signal transduction mechanisms	Neurotransmitter-gated ion-channel ligand binding domain;; Neurotransmitter-gated ion-channel transmembrane region	Gamma-aminobutyric acid receptor subunit theta (Precursor) GN=GABRQ OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: gamma-aminobutyric acid receptor subunit theta [Ochotona princeps]
ENSG00000268104(SLC6A14)	--	0.0322573	2	0.0317167	2	0.0481532	2	0.602503	38	0.89061	55	0.880367	55	7.63E-06	3.459278289	up	7.09E-10	3.991560949	up	5.56E-10	4.001686938	up	1.67E-12	4.604444517	up	[R]	General function prediction only	Molecular Function: neurotransmitter:sodium symporter activity (GO:0005328);; Biological Process: neurotransmitter transport (GO:0006836);; Cellular Component: integral component of membrane (GO:0016021);; 	"K05038|0|hsa:11254|SLC6A14, BMIQ11; solute carrier family 6 (amino acid transporter), member 14; K05038 solute carrier family 6 (neurotransmitter transporter, amino acid) member 5/7/9/14 (A)"	--	[T]	Signal transduction mechanisms	Sodium:neurotransmitter symporter family	Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) GN=SLC6A14 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) [Galeopterus variegatus]
ENSG00000268182(SMIM17)	--	0.135308	2	0	0	0	0	0	0	0.3548397	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Small integral membrane protein 17 GN=SMIM17 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	PREDICTED: small integral membrane protein 17 [Tupaia chinensis]
ENSG00000268350(FAM156A)	--	0.391919105	13	0.595464931	20	0.231997176	8	0.848378204	28	0.71623719	36	0.684436792	24	0.904168775	0.994419689	normal	0.912535241	0.781960809	normal	0.752469114	1.415941459	normal	0.096161975	1.079227994	normal	--	--	Molecular Function: methylated histone binding (GO:0035064);; 	--	--	--	--	PGC7/Stella/Dppa3 domain	Protein FAM156A/FAM156B GN=FAM156B OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein FAM156A/FAM156B [Galeopterus variegatus]
ENSG00000268655(CTB-60B18.10)	--	0.437087	10	0.481012	11	0.417382	9	0.0431342	1	0.209263	4	0.0852329	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	R	General function prediction only	hypothetical protein PANDA_006292 [Ailuropoda melanoleuca]
ENSG00000268916(CSAG3)	--	0	0	0	0	0	0	0.0790338	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Chondrosarcoma-associated gene 2/3 protein GN=CSAG3 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: chondrosarcoma-associated gene 2/3 protein-like [Chrysochloris asiatica]
ENSG00000268991(FAM231B)	--	0	0	0	0	0	0	0	0	0	0	0.414307	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein FAM231B GN=FAM231B OS=Homo sapiens (Human) PE=3 SV=1	S	Function unknown	--
ENSG00000269028(MTRNR2L12)	--	81.1713	1218	61.954	912	62.1845	916	82.1765	1268	74.9814	1136	77.3395	1189	0.981768643	0.027174752	normal	0.909106556	0.294991509	normal	0.804036093	0.367503784	normal	0.312120945	0.216649062	normal	--	--	--	--	--	--	--	--	Humanin-like 8 {ECO:0000305} OS=Homo sapiens (Human) PE=2 SV=1	--	--	--
ENSG00000269058(CALR3)	--	0.053640362	1	0	0	0.154104653	2	0.103718883	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: calcium ion binding (GO:0005509);; Cellular Component: endoplasmic reticulum (GO:0005783);; Biological Process: protein folding (GO:0006457);; Molecular Function: unfolded protein binding (GO:0051082);; 	"K10098|0|hsa:125972|CALR3, CMH19, CRT2, CT93; calreticulin 3; K10098 calreticulin 3 (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Calreticulin family	Calreticulin-3 (Precursor) GN=CALR3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: calreticulin-3 isoform X2 [Canis lupus familiaris]
ENSG00000269096(CT45A3)	--	0.0753695	1	0.223127542	3	0	0	0	0	0	0	0.05633764	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	INTS6/SAGE1/DDX26B/CT45 C-terminus	Cancer/testis antigen family 45 member A3 GN=CT45A3 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	Protein DDX26B [Pteropus alecto]
ENSG00000269113(TRABD2B)	--	0.08595	13	0.0784601	12	0.0258087	3	0.0531827	8	0.0322414	4	0.104978	16	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TraB family	Metalloprotease TIKI2 (Precursor) GN=TRABD2B OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: metalloprotease TIKI2 [Pteropus alecto]
ENSG00000269226(RP11-722G7.1)	--	0.451549	15	0.4578301	13	0.386481	12	0.294437	10	0.3560838	9	0.264883	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative binding domain;; Thymosin beta-4 family	KN motif and ankyrin repeat domain-containing protein 3 GN=KANK3 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: UPF0764 protein C16orf89-like [Camelus ferus]
ENSG00000269313(MAGIX)	--	0.917312818	31	1.497766671	46	1.521172756	52	1.0513959	19	1.114337453	36	1.039813618	29	0.952594208	-0.692820483	normal	0.966441794	-0.361591103	normal	0.782298117	-0.818448653	normal	0.297641477	-0.63830171	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	PDZ domain (Also known as DHR or GLGF)	PDZ domain-containing protein MAGIX GN=MAGIX OS=Homo sapiens (Human) PE=1 SV=3	R	General function prediction only	"PREDICTED: PDZ domain-containing protein MAGIX, partial [Camelus ferus]"
ENSG00000269335(IKBKG)	--	21.390209	860	22.334187	927	20.88072	976	21.197791	854	22.915828	871	25.08520039	902	0.977091406	-0.040859599	normal	0.972597066	-0.111136094	normal	0.972530873	-0.121848705	normal	0.705020801	-0.093695383	normal	--	--	--	"K07210|0|hsa:8517|IKBKG, AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IMD33, IP, IP1, IP2, IPD2, NEMO, ZC2HC9; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; K07210 inhibitor of nuclear factor kappa-B kinase subunit gamma (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; NF-kappa B signaling pathway (ko04064);; PI3K-Akt signaling pathway (ko04151);; Apoptosis (ko04210);; Osteoclast differentiation (ko04380);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; RIG-I-like receptor signaling pathway (ko04622);; Cytosolic DNA-sensing pathway (ko04623);; T cell receptor signaling pathway (ko04660);; B cell receptor signaling pathway (ko04662);; TNF signaling pathway (ko04668);; Adipocytokine signaling pathway (ko04920);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Shigellosis (ko05131);; Chagas disease (American trypanosomiasis) (ko05142);; Toxoplasmosis (ko05145);; Hepatitis C (ko05160);; Hepatitis B (ko05161);; HTLV-I infection (ko05166);; Herpes simplex infection (ko05168);; Epstein-Barr virus infection (ko05169);; Pathways in cancer (ko05200);; Viral carcinogenesis (ko05203);; Pancreatic cancer (ko05212);; Prostate cancer (ko05215);; Chronic myeloid leukemia (ko05220);; Acute myeloid leukemia (ko05221);; Small cell lung cancer (ko05222);; Primary immunodeficiency (ko05340)	--	--	NF-kappa-B essential modulator NEMO	NF-kappa-B essential modulator GN=IKBKG OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	hypothetical protein PANDA_019995 [Ailuropoda melanoleuca]
ENSG00000269556(TMEM185A)	--	10.633585	455	11.0376107	443	10.12851339	462	13.7570661	578	15.28674178	576	17.0404442	633	0.877927545	0.313429821	normal	0.823712054	0.356266284	normal	0.590840952	0.444772482	normal	0.060884845	0.373062747	normal	--	--	--	--	--	[S]	Function unknown	Transmembrane Fragile-X-F protein	Transmembrane protein 185A GN=TMEM185A OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: transmembrane protein 185A-like [Echinops telfairi]
ENSG00000269713(NBPF9)	--	6.372209514	851	6.136758454	830	6.019868128	819	6.35117806	850	5.924151972	794	6.388776402	855	0.9772462	-0.032469897	normal	0.973561107	-0.085240076	normal	0.976399075	0.053672523	normal	0.9508736	-0.021819257	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220)	Neuroblastoma breakpoint family member 20 GN=NBPF20 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4-like isoform X1 [Bos taurus]
ENSG00000269743(SLC25A53)	--	1.3997766	148	1.3394483	144	1.081484492	119	1.426440857	154	1.3540313	147	1.414098818	155	0.967667813	0.026233931	normal	0.966708019	0.008235189	normal	0.894941311	0.36889631	normal	0.793791908	0.128359879	normal	--	--	--	--	--	[R]	General function prediction only	Mitochondrial carrier protein	Solute carrier family 25 member 53 GN=SLC25A53 OS=Homo sapiens (Human) PE=2 SV=1	C	Energy production and conversion	PREDICTED: solute carrier family 25 member 53-like [Ceratotherium simum simum]
ENSG00000269855(RNF225)	--	0	0	0	0	0	0	0	0	0.110037	0	0.223248	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metal ion binding (GO:0046872);; 	--	--	[O]	"Posttranslational modification, protein turnover, chaperones"	"Ring finger domain;; zinc finger of C3HC4-type, RING;; Zinc finger, C3HC4 type (RING finger);; zinc-RING finger domain;; Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger)"	RING finger protein 225 {ECO:0000312|HGNC:HGNC:51249} OS=Homo sapiens (Human) PE=3 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: RING finger protein 223-like [Canis lupus familiaris]
ENSG00000269858(EGLN2)	--	56.45611893	2014	64.49235051	2443	54.46017868	2114	55.774098	2076	57.30090553	2080	66.087644	2433	0.987037266	0.012900803	normal	0.958258926	-0.253326729	normal	0.974790695	0.194339814	normal	0.957360601	-0.016915597	normal	--	--	Molecular Function: oxidoreductase activity (GO:0016491);; Biological Process: oxidation-reduction process (GO:0055114);; 	K09592|0|ptr:456049|EGLN2; egl-9 family hypoxia-inducible factor 2 (EC:1.14.11.29); K09592 hypoxia-inducible factor prolyl hydroxylase [EC:1.14.11.29] (A)	HIF-1 signaling pathway (ko04066);; Pathways in cancer (ko05200);; Renal cell carcinoma (ko05211)	[T]	Signal transduction mechanisms	2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily;; 2OG-Fe(II) oxygenase superfamily	Egl nine homolog 2 GN=EGLN2 OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: egl nine homolog 2 isoform X1 [Sus scrofa] 
ENSG00000270168(LA16c-380H5.3)	--	0.0694097	3	0	0	0	0	0.046159	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: collagen alpha-1(III) chain-like [Sus scrofa]
ENSG00000270170(NCBP2-AS2)	--	14.81058	209	14.383403	206	16.454083	233	20.737141	276	19.98933	273	15.344813	211	0.84539394	0.367972764	normal	0.828447404	0.382384493	normal	0.957149337	-0.150352461	normal	0.535216031	0.20830903	normal	--	--	--	--	--	--	--	--	Uncharacterized protein NCBP2-AS2 GN=NCBP2-AS2 OS=Homo sapiens (Human) PE=4 SV=1	S	Function unknown	hypothetical protein PAL_GLEAN10007378 [Pteropus alecto]
ENSG00000270276(HIST2H4B)	--	6.93085	98	6.5307	95	4.73095	69	2.19964	32	3.8023	54	3.04346	44	6.46E-05	-1.599382292	down	0.355800621	-0.818872318	normal	0.835730187	-0.63968335	normal	0.012972238	-1.031766419	normal	[B]	Chromatin structure and dynamics	"Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000270629(NBPF14)	--	2.527384293	282	2.807260782	242	2.837678676	276	3.977218741	333	3.872537689	321	3.019582188	321	0.943470213	0.20795125	normal	0.811159063	0.384049761	normal	0.943530271	0.208553064	normal	0.341105299	0.26422108	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220);; Euplotes octocarinatus mating pheromone protein;; Speriolin C-terminus	Neuroblastoma breakpoint family member 20 GN=NBPF20 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4 [Bos taurus] 
ENSG00000270647(TAF15)	--	126.993618	5692	127.9860638	6039	129.6070694	6010	166.570527	7471	141.9384424	6389	131.4946021	6017	0.923640146	0.361448056	normal	0.993843912	0.059839339	normal	0.994306863	-0.006610414	normal	0.508085651	0.142162174	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	"K14651|9.2653e-111|rno:287571|Taf15; TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor; K14651 transcription initiation factor TFIID subunit 15 (A)"	Basal transcription factors (ko03022);; Transcriptional misregulation in cancer (ko05202)	[R]	General function prediction only	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif (a.k.a. RRM, RBD, or RNP domain);; Zn-finger in Ran binding protein and others"	TATA-binding protein-associated factor 2N GN=TAF15 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: TATA-binding protein-associated factor 2N-like [Ovis aries]
ENSG00000270765(GAS2L2)	--	0.06507468	4	0.14416172	10	0.0269439	1	0	0	0.110819758	6	0.130232426	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; Molecular Function: microtubule binding (GO:0008017);; 	--	--	[Z]	Cytoskeleton	Growth-Arrest-Specific Protein 2 Domain;; Calponin homology (CH) domain	GAS2-like protein 2 GN=GAS2L2 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: GAS2-like protein 2 [Ceratotherium simum simum]
ENSG00000270806(C17orf50)	--	0.26535177	4	0.514615548	6	0.962213	13	0.1316514	2	0.180430485	1	0.130033832	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4637)	Uncharacterized protein C17orf50 GN=C17orf50 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: uncharacterized protein C17orf50 homolog [Equus caballus]
ENSG00000270885(RASL10B)	--	0.396752	24	0.2873	18	0.471939	29	0.0493619	3	0.128733	7	0.0978814	6	0.037799457	-2.517607214	normal	--	--	--	0.075913324	-2.029317628	normal	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07851|3.75401e-149|ocu:100347773|RASL10B; RAS-like, family 10, member B; K07851 Ras-like protein family member 10B (A)"	--	[R]	General function prediction only	Ras family;; Miro-like protein	Ras-like protein family member 10B (Precursor) GN=RASL10B OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	ras-like protein family member 10B [Bos taurus] 
ENSG00000271254(AC240274.1)	--	6.953342843	428	4.363759769	290	5.639659842	368	7.513766926	469	8.170190406	512	4.157437392	290	0.965852256	0.100799131	normal	0.003637031	0.795502667	normal	0.846288368	-0.350318611	normal	0.702729371	0.204744109	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220)	Neuroblastoma breakpoint family member 11 GN=NBPF11 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4-like isoform X1 [Bos taurus]
ENSG00000271383(NBPF19)	--	2.184508766	203	2.031065874	194	2.177212609	205	2.321425141	218	1.89333321	175	2.156683527	209	0.965003322	0.071493941	normal	0.954131908	-0.168742568	normal	0.96685091	0.019445519	normal	0.974200785	-0.021349734	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220);; Euplotes octocarinatus mating pheromone protein;; Speriolin C-terminus	Neuroblastoma breakpoint family member 14 GN=NBPF14 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4 [Bos taurus] 
ENSG00000271425(NBPF10)	--	0.367135594	129	0.293121166	103	0.297668409	103	0.490553114	171	0.388258757	134	0.416293195	145	0.885190515	0.371934856	normal	0.91255315	0.353599114	normal	0.804405935	0.479160428	normal	0.281132274	0.403810487	normal	--	--	--	--	--	--	--	Repeat of unknown function (DUF1220);; Euplotes octocarinatus mating pheromone protein;; Speriolin C-terminus	Neuroblastoma breakpoint family member 20 GN=NBPF20 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: neuroblastoma breakpoint family member 4 [Bos taurus] 
ENSG00000271447(MMP28)	--	0.528598	8	0.1242727	4	0.243761	3	1.10348176	18	1.074098048	19	0.3530194	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Molecular Function: zinc ion binding (GO:0008270);; Cellular Component: extracellular matrix (GO:0031012);; 	K08006|0|pps:100968823|MMP28; matrix metallopeptidase 28; K08006 matrix metalloproteinase-28 (epilysin) [EC:3.4.24.-] (A)	--	[OW]	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	Matrixin;; Hemopexin;; Putative peptidoglycan binding domain	Matrix metalloproteinase-28 (Precursor) GN=MMP28 OS=Homo sapiens (Human) PE=2 SV=2	OW	"Posttranslational modification, protein turnover, chaperones;; Extracellular structures"	PREDICTED: matrix metalloproteinase-28 [Ceratotherium simum simum]
ENSG00000271503(CCL5)	--	0.477402317	10	0.142286915	3	0.742022119	15	0.373055913	8	0.214025754	4	0.217133935	5	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K12499|1.14411e-96|hsa:6352|CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP; chemokine (C-C motif) ligand 5; K12499 C-C motif chemokine 5 (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062);; Toll-like receptor signaling pathway (ko04620);; NOD-like receptor signaling pathway (ko04621);; Cytosolic DNA-sensing pathway (ko04623);; TNF signaling pathway (ko04668);; Prion diseases (ko05020);; Epithelial cell signaling in Helicobacter pylori infection (ko05120);; Chagas disease (American trypanosomiasis) (ko05142);; Influenza A (ko05164);; Herpes simplex infection (ko05168);; Rheumatoid arthritis (ko05323)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	RANTES(4-68) (Precursor) GN=CCL5 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	C-C motif chemokine 5 [Tupaia chinensis]
ENSG00000271601(LIX1L)	--	9.35694	526	8.386546	473	9.14599	512	11.45988	649	10.09543	565	9.70968	548	0.915110655	0.271608144	normal	0.934922265	0.234297984	normal	0.968735695	0.089485119	normal	0.39199123	0.200038264	normal	--	--	--	K16673|0|ptr:457984|LIX1L; Lix1 homolog (chicken) like; K16673 LIX1-like protein (A)	--	--	--	Limb expression 1	LIX1-like protein GN=LIX1L OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LIX1-like protein [Equus przewalskii]
ENSG00000271605(MILR1)	--	3.932956028	118	2.858990579	87	1.803510411	97	8.317969309	228	7.21463912	296	6.8804533	219	0.005827128	0.910741575	normal	7.25E-12	1.72781052	up	8.25E-05	1.154284083	up	6.78E-07	1.277630607	up	--	--	--	--	--	--	--	Immunoglobulin domain;; Immunoglobulin domain	Allergin-1 (Precursor) GN=MILR1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: allergin-1 isoform X3 [Equus caballus] 
ENSG00000271824(AC009014.3)	--	0.279816	7	0.114079	3	0	0	0.0392136	1	0.114926	2	0.155765	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	Short transient receptor potential channel 7 [Pteropus alecto]
ENSG00000272031(ANKRD34A)	--	0.7823944	37	0.54864202	32	0.872327476	34	0.257544	13	0.5080354	19	0.228333115	16	0.281366108	-1.435135869	normal	0.939906668	-0.728355122	normal	0.813781671	-1.027707628	normal	0.063151572	-1.122005379	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	--	--	Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeat;; Ankyrin repeats (many copies)	Ankyrin repeat domain-containing protein 34A GN=ANKRD34A OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 34A [Camelus ferus]
ENSG00000272047(GTF2H5)	--	2.835650286	361	2.842750449	360	2.837357	354	3.168500328	405	2.648690463	337	2.8228954	360	0.960313149	0.134549976	normal	0.961366224	-0.116170363	normal	0.968818942	0.015888795	normal	0.978007411	0.014135089	normal	--	--	--	"K10845|5.33383e-44|umr:103660850|GTF2H5; general transcription factor IIH, polypeptide 5; K10845 TFIIH basal transcription factor complex TTD-A subunit (A)"	Basal transcription factors (ko03022);; Nucleotide excision repair (ko03420)	[S]	Function unknown	Transcription factor TFIIH complex subunit Tfb5	General transcription factor IIH subunit 5 GN=GTF2H5 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: general transcription factor IIH subunit 5 [Capra hircus]
ENSG00000272196(HIST2H2AA4)	--	2.1825	12	2.10855	12	3.22571	18	2.05383	12	1.21765	6	3.32262	19	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.32556e-71|ssc:100624086|histone H2A type 2-C-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 2-A GN=HIST2H2AA4 OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-A-like [Sus scrofa] 
ENSG00000272333(KMT2B)	--	13.2579	2611	14.4478	2856	14.9068	2981	12.788	2491	13.2144	2582	14.6182	2892	0.986622344	-0.098650257	normal	0.981442217	-0.166840574	normal	0.989511843	-0.051993484	normal	0.627811815	-0.105540106	normal	[R]	General function prediction only	Molecular Function: DNA binding (GO:0003677);; Molecular Function: protein binding (GO:0005515);; Cellular Component: nucleus (GO:0005634);; Molecular Function: zinc ion binding (GO:0008270);; 	"K14959|0|hsa:9757|KMT2B, HRX2, MLL1B, MLL2, MLL4, TRX2, WBP-7, WBP7; lysine (K)-specific methyltransferase 2B (EC:2.1.1.43); K14959 histone-lysine N-methyltransferase MLL4 [EC:2.1.1.43] (A)"	Lysine degradation (ko00310)	[K]	Transcription	SET domain;; F/Y rich C-terminus;; F/Y-rich N-terminus;; PHD-finger;; PHD-like zinc-binding domain;; CXXC zinc finger domain;; PHD-zinc-finger like domain	Histone-lysine N-methyltransferase 2B GN=KMT2B OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: histone-lysine N-methyltransferase MLL4-like [Ceratotherium simum simum]
ENSG00000272391(POM121C)	--	14.5655871	1665	13.97347366	1575	17.06323084	1625	18.47107652	1990	17.19121291	1949	16.14723207	1798	0.962553562	0.226222851	normal	0.934024299	0.285708697	normal	0.978996108	0.137540128	normal	0.224890421	0.216396817	normal	--	--	--	K14316|0|ggo:101131483|LOW QUALITY PROTEIN: nuclear envelope pore membrane protein POM 121C-like; K14316 nuclear pore complex protein Nup121 (A)	RNA transport (ko03013)	--	--	POM121 family	Nuclear envelope pore membrane protein POM 121C GN=POM121C OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: nuclear envelope pore membrane protein POM 121 [Galeopterus variegatus]
ENSG00000272398(CD24)	--	79.18333139	2591	89.91432195	2895	89.49761166	2849	328.3479033	10649	344.3127918	11223	460.0909689	14950	0	2.007669004	up	0	1.932844548	up	0	2.382709466	up	1.46E-12	2.123181057	up	--	--	Biological Process: cell adhesion (GO:0007155);; 	--	--	--	--	CD24 protein	--	--	--	--
ENSG00000272514(CFAP206)	--	0.604228125	23	1.018444082	41	0.250181544	9	0.37136555	15	0.506238506	20	0.123452042	5	0.977058722	-0.597711125	normal	0.718966115	-1.00301135	normal	--	--	--	0.527901597	-0.892846307	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF3508)	UPF0704 protein C6orf165 GN=C6orf165 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: UPF0704 protein C6orf165 homolog isoform X5 [Tupaia chinensis]
ENSG00000272602(ZNF595)	--	9.407083257	208	10.07651968	224	9.82279622	199	19.37157873	352	16.52522044	293	15.91763312	310	0.032559034	0.724005426	normal	0.845184791	0.363822075	normal	0.175263756	0.627358371	normal	0.014970475	0.576052935	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:471114|ZNF595; zinc finger protein 595; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; XPA protein N-terminal;; Probable zinc-binding domain"	Zinc finger protein 595 GN=ZNF595 OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	"Zinc finger protein 91, partial [Bos mutus]"
ENSG00000272636(DOC2B)	--	0.118591	16	0.0512112	7	0.0645889	8	0.00742225	1	0.0215678	2	0.014648	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Double C2-like domain-containing protein beta GN=DOC2B OS=Homo sapiens (Human) PE=1 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: double C2-like domain-containing protein beta [Oryctolagus cuniculus]
ENSG00000272886(DCP1A)	--	4.85779	540	5.137321	561	5.020624252	547	4.448161	481	5.1105283	522	4.0965971	446	0.948911564	-0.197159952	normal	0.964269648	-0.12502802	normal	0.890083955	-0.301862646	normal	0.382138622	-0.207023786	normal	--	--	Biological Process: deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0000290);; Molecular Function: enzyme activator activity (GO:0008047);; Biological Process: positive regulation of catalytic activity (GO:0043085);; 	K12610|0|pps:100976251|DCP1A; decapping mRNA 1A; K12610 mRNA-decapping enzyme 1A [EC:3.-.-.-] (A)	RNA degradation (ko03018)	[KA]	Transcription;; RNA processing and modification	Dcp1-like decapping family	mRNA-decapping enzyme 1A GN=DCP1A OS=Homo sapiens (Human) PE=1 SV=2	AK	RNA processing and modification;; Transcription	PREDICTED: mRNA-decapping enzyme 1A isoform 1 [Ceratotherium simum simum]
ENSG00000272899(RP11-309L24.4)	--	0.352217	23	0.456688	30	0.296767	19	0.352772	23	0.740754	48	1.05488	70	0.987850059	-0.028901613	normal	0.915094199	0.631286916	normal	0.000263373	1.793804614	up	0.278983094	0.950889591	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC103676643 [Ursus maritimus]
ENSG00000273045(C2orf15)	--	1.482057	55	1.045468077	49	1.449625	49	0.85648	44	2.008918	55	1.522932054	70	0.964131058	-0.342052493	normal	0.974912741	0.141111077	normal	0.917273689	0.493477115	normal	0.883493494	0.12361835	normal	--	--	--	--	--	--	--	--	Uncharacterized protein C2orf15 GN=C2orf15 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C2orf15 homolog [Trichechus manatus latirostris]
ENSG00000273079(GRIN2B)	--	0.684926887	90	0.492004978	110	1.011090311	100	0.573191992	79	0.704671203	83	0.72144823	84	0.962719887	-0.214983812	normal	0.894381309	-0.421059231	normal	0.954765624	-0.255607085	normal	0.535069027	-0.307335327	normal	--	--	Molecular Function: ionotropic glutamate receptor activity (GO:0004970);; Molecular Function: extracellular-glutamate-gated ion channel activity (GO:0005234);; Cellular Component: membrane (GO:0016020);; 	"K05210|0|pon:100458706|GRIN2B; glutamate receptor, ionotropic, N-methyl D-aspartate 2B; K05210 glutamate receptor ionotropic, NMDA 2B (A)"	Ras signaling pathway (ko04014);; Rap1 signaling pathway (ko04015);; cAMP signaling pathway (ko04024);; Neuroactive ligand-receptor interaction (ko04080);; Circadian entrainment (ko04713);; Long-term potentiation (ko04720);; Glutamatergic synapse (ko04724);; Dopaminergic synapse (ko04728);; Alzheimer's disease (ko05010);; Amyotrophic lateral sclerosis (ALS) (ko05014);; Huntington's disease (ko05016);; Cocaine addiction (ko05030);; Amphetamine addiction (ko05031);; Nicotine addiction (ko05033);; Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[PET]	Inorganic ion transport and metabolism;; Amino acid transport and metabolism;; Signal transduction mechanisms	"N-methyl D-aspartate receptor 2B3 C-terminus;; Ligand-gated ion channel;; Bacterial extracellular solute-binding proteins, family 3;; Ligated ion channel L-glutamate- and glycine-binding site;; Receptor family ligand binding region"	"Glutamate receptor ionotropic, NMDA 2B (Precursor) GN=GRIN2B OS=Homo sapiens (Human) PE=1 SV=3"	T	Signal transduction mechanisms	"PREDICTED: glutamate receptor ionotropic, NMDA 2B [Pteropus alecto]"
ENSG00000273136(NBPF26)	--	0.842782839	71	0.731980275	58	0.887937302	73	0.759451323	69	0.837097693	74	0.851157313	73	0.974233352	-0.070507092	normal	0.95356409	0.322584073	normal	0.974209203	-0.008123161	normal	0.926368368	0.07594839	normal	--	--	Molecular Function: calcium ion binding (GO:0005509);; 	--	--	--	--	Repeat of unknown function (DUF1220);; EGF-like domain;; Calcium-binding EGF domain;; Human growth factor-like EGF	Neuroblastoma breakpoint family member 1 GN=NBPF1 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: neurogenic locus notch homolog protein 2 [Tupaia chinensis]
ENSG00000273274(ZBTB8B)	--	0.00463727	1	0	0	0.0137696	2	0.0230727	5	0.00450002	0	0.0230256	5	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	"K10495|0|hsa:728116|ZBTB8B, ZNF916B; zinc finger and BTB domain containing 8B; K10495 zinc finger and BTB domain-containing protein 8 (A)"	--	[R]	General function prediction only	"BTB/POZ domain;; Zinc-finger double domain;; C2H2-type zinc finger;; Zinc finger, C2H2 type"	Zinc finger and BTB domain-containing protein 8B GN=ZBTB8B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: zinc finger and BTB domain-containing protein 8B [Galeopterus variegatus]
ENSG00000273496(AC011841.1)	--	0	0	0	0	0.0907575	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	--
ENSG00000273514(FOXD4L6)	--	0	0	0.122803	4	0	0	0	0	0.029816	0	0.0302541	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	K09397|0|hsa:653404|FOXD4L6; forkhead box D4-like 6; K09397 forkhead box protein D (A)	--	[K]	Transcription	Fork head domain	Forkhead box protein D4-like 6 GN=FOXD4L6 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: forkhead box protein D4 [Equus caballus]
ENSG00000273542(HIST1H4K)	--	0.34102	14	0.315878	13	0.556922	22	0.410519	17	0.328326	13	0.19243	8	--	--	--	--	--	--	0.853195633	-1.312916405	normal	--	--	--	[B]	Chromatin structure and dynamics	"Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000273559(CWC25)	--	8.03021	592	7.66963	572	7.93174	585	8.03686	593	9.68421	708	8.19832	604	0.973172937	-0.028323888	normal	0.90650239	0.285627798	normal	0.973043669	0.037724505	normal	0.708230634	0.102231296	normal	--	--	--	--	--	[S]	Function unknown	Pre-mRNA splicing factor;; N-terminal domain of CBF1 interacting co-repressor CIR	Pre-mRNA-splicing factor CWC25 homolog GN=CWC25 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: pre-mRNA-splicing factor CWC25 homolog [Pteropus alecto]
ENSG00000273590(SMIM11B)	--	0.417977608	10	0.32062966	9	0.515104602	12	0.239565037	6	0.330411049	9	0.202794356	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	--
ENSG00000273604(EPOP)	--	10.3214	684	8.95078	603	8.80323	600	12.5936	841	12.0651	799	9.656	649	0.922382172	0.266736113	normal	0.767199579	0.383772363	normal	0.969131349	0.104710718	normal	0.197926382	0.256607887	normal	--	--	--	--	--	--	--	Domain of unknown function (DUF4584)	Uncharacterized protein C17orf96 GN=C17orf96 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: uncharacterized protein C17orf96 homolog [Odobenus rosmarus divergens]
ENSG00000273611(ZNHIT3)	--	44.242061	611	43.014064	597	44.992419	630	46.05874	650	47.027815	652	58.103128	819	0.972718991	0.05829295	normal	0.968357182	0.105458798	normal	0.792441427	0.36944026	normal	0.408034039	0.186176185	normal	--	--	--	--	--	[K]	Transcription	HIT zinc finger	Zinc finger HIT domain-containing protein 3 GN=ZNHIT3 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger HIT domain-containing protein 3 isoform X1 [Galeopterus variegatus]
ENSG00000273706(LHX1)	--	2.176961792	179	0.8766469	80	1.411953	123	2.125221	178	2.246159	187	0.976069	70	0.966704562	-0.03858251	normal	0.000159848	1.188427233	up	0.206991472	-0.808178476	normal	0.883493494	0.164268955	normal	[K]	Transcription	"Molecular Function: DNA binding (GO:0003677);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09372|0|hsa:3975|LHX1, LIM-1, LIM1; LIM homeobox 1; K09372 LIM homeobox protein 1 (A)"	--	[R]	General function prediction only	LIM domain;; Homeobox domain;; Homeobox KN domain	LIM/homeobox protein Lhx1 GN=LHX1 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: LIM/homeobox protein Lhx1 [Camelus bactrianus]
ENSG00000273748(AL592183.1)	--	4.698449869	143	5.323876131	174	5.491024208	177	4.902678314	194	4.872889674	192	5.92469854	230	0.841536816	0.405456868	normal	0.960454181	0.119602612	normal	0.861847707	0.366836142	normal	0.387084035	0.297883446	normal	--	--	--	K13122|2.70772e-61|cjc:100402668|FRG1; FSHD region gene 1; K13122 protein FRG1 (A)	--	[Z]	Cytoskeleton	FRG1-like family	Protein FRG1B GN=FRG1B OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	hypothetical protein PANDA_013056 [Ailuropoda melanoleuca]
ENSG00000273749(CYFIP1)	--	54.35382723	5044	48.74703925	4536	47.7982559	4722	47.03429062	4573	44.30864601	4183	44.01387745	4391	0.987502735	-0.172204499	normal	0.988919059	-0.138261182	normal	0.990765139	-0.113102377	normal	0.494753015	-0.142831872	normal	--	--	--	"K05749|0|ptr:453278|CYFIP1, TUBGCP5; cytoplasmic FMR1 interacting protein 1; K05749 cytoplasmic FMR1 interacting protein (A)"	RNA transport (ko03013);; Regulation of actin cytoskeleton (ko04810)	[R]	General function prediction only	Cytoplasmic Fragile-X interacting family	Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: cytoplasmic FMR1-interacting protein 1 [Oryctolagus cuniculus] 
ENSG00000273802(HIST1H2BG)	--	0	0	0.0441214	1	0	0	0.044067	1	0.0431997	0	0.0442293	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|5.83049e-60|lve:103082925|histone H2B type 1-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-N GN=HIST1H2BN OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5-like [Bubalus bubalis]
ENSG00000273820(USP27X)	--	3.12662	173	2.95305	165	2.41034	133	2.43697	135	2.54814	140	2.05888	114	0.871845564	-0.38476523	normal	0.938005065	-0.255916085	normal	0.951729378	-0.227882197	normal	0.451619069	-0.297976506	normal	--	--	Biological Process: protein deubiquitination (GO:0016579);; Molecular Function: ubiquitinyl hydrolase activity (GO:0036459);; 	"K11366|0|mcf:102129317|USP27X; ubiquitin specific peptidase 27, X-linked; K11366 ubiquitin carboxyl-terminal hydrolase 22/27/51 [EC:3.4.19.12] (A)"	--	[O]	"Posttranslational modification, protein turnover, chaperones"	Ubiquitin carboxyl-terminal hydrolase;; Ubiquitin carboxyl-terminal hydrolase	Ubiquitin carboxyl-terminal hydrolase 27 GN=USP27X OS=Homo sapiens (Human) PE=2 SV=3	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: ubiquitin carboxyl-terminal hydrolase 27 [Odobenus rosmarus divergens]
ENSG00000273899(NOL12)	--	11.42087	265	11.9006	294	10.69279	268	10.38686	242	10.55668	255	7.98427	196	0.954966308	-0.160841252	normal	0.937381929	-0.225498756	normal	0.699218348	-0.456645077	normal	0.351079854	-0.276844274	normal	--	--	--	"K14851|9.14861e-109|hsa:79159|NOL12, Nop25, dJ37E16.7; nucleolar protein 12; K14851 ribosomal RNA-processing protein 17 (A)"	--	[S]	Function unknown	Nucleolar protein 12 (25kDa)	Nucleolar protein 12 GN=NOL12 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: nucleolar protein 12 [Camelus ferus] 
ENSG00000273983(HIST1H3G)	--	0	0	0.067493	2	0.0672061	1	0.0667943	2	0.0327714	0	0.0671293	2	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000274070(GATSL2)	--	6.887236837	506	6.921213571	481	6.923874512	520	5.635672	405	6.396317	432	5.873944	420	0.831315846	-0.35085404	normal	0.953055921	-0.175848404	normal	0.876882249	-0.315391103	normal	0.209035795	-0.282641935	normal	[S]	Function unknown	--	--	--	--	--	ACT domain	GATS-like protein 2 GN=GATSL2 OS=Homo sapiens (Human) PE=2 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: GATS-like protein 2 [Sus scrofa]
ENSG00000274180(NATD1)	--	3.667584	347	2.902668	278	3.18006	304	3.256991	307	3.022087	283	4.37736	414	0.943769785	-0.206556127	normal	0.966518821	0.004267604	normal	0.672167224	0.435404902	normal	0.833277129	0.091683248	normal	[R]	General function prediction only	--	"K06975|3.81021e-78|ptr:740609|NATD1, C17H17orf103; N-acetyltransferase domain containing 1; K06975 (A)"	--	--	--	GCN5-related N-acetyl-transferase	Protein NATD1 GN=NATD1 OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	PREDICTED: protein GTLF3B [Pteropus alecto]
ENSG00000274183(H2AFB1)	--	0	0	0	0	0.453359	2	0	0	0	0	0.159038	1	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	--	"K11251|6.51077e-64|hsa:474382|H2AFB1, H2A.Bbd; H2A histone family, member B1; K11251 histone H2A (A)"	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H2A-Bbd type 1 GN=H2AFB1 OS=Homo sapiens (Human) PE=2 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone H2A-Bbd type 2/3-like [Camelus bactrianus]
ENSG00000274209(ANTXRL)	--	0	0	0.025233006	1	0.0431195	1	0.022129864	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: receptor activity (GO:0004872);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	Anthrax receptor extracellular domain;; von Willebrand factor type A domain;; von Willebrand factor type A domain	Anthrax toxin receptor-like (Precursor) GN=ANTXRL OS=Homo sapiens (Human) PE=2 SV=3	R	General function prediction only	PREDICTED: anthrax toxin receptor-like [Tupaia chinensis]
ENSG00000274211(SOCS7)	--	8.086708804	1238	8.509859308	1343	7.558868327	1127	6.504006475	1006	7.719618451	1151	7.62475695	1176	0.870975865	-0.329758302	normal	0.947215263	-0.243701258	normal	0.980222632	0.053039425	normal	0.375580777	-0.1747647	normal	--	--	Biological Process: intracellular signal transduction (GO:0035556);; 	"K04699|0|hsa:30837|SOCS7, NAP4, NCKAP4; suppressor of cytokine signaling 7; K04699 suppressor of cytokine signaling 7 (A)"	Jak-STAT signaling pathway (ko04630);; Prolactin signaling pathway (ko04917)	[T]	Signal transduction mechanisms	SOCS box;; SH2 domain	Suppressor of cytokine signaling 7 GN=SOCS7 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: suppressor of cytokine signaling 7 [Condylura cristata]
ENSG00000274267(HIST1H3B)	--	3.764416	20	1.767780051	26	0.539810231	7	0.972061	11	1.029108	13	1.943544	16	0.9705918	-0.808494098	normal	0.922377022	-0.942522641	normal	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	--	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000274286(ADRA2B)	--	0.0508768	3	0	0	0.0163269	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04139|0|hsa:151|ADRA2B, ADRA2L1, ADRA2RL1, ADRARL1, ALPHA2BAR, alpha-2BAR; adrenoceptor alpha 2B; K04139 adrenergic receptor alpha-2B (A)"	cGMP-PKG signaling pathway (ko04022);; Neuroactive ligand-receptor interaction (ko04080)	[R]	General function prediction only	7 transmembrane receptor (rhodopsin family);; Serpentine type 7TM GPCR chemoreceptor Srsx;; Serpentine type 7TM GPCR chemoreceptor Srx	Alpha-2B adrenergic receptor GN=ADRA2B OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: alpha-2B adrenergic receptor [Odobenus rosmarus divergens]
ENSG00000274349(ZNF658)	--	2.8414576	256	2.568222676	213	2.65070848	236	1.920413652	152	1.92860181	170	2.2046947	198	0.030664142	-0.776781358	normal	0.884918676	-0.344004918	normal	0.929307492	-0.259758171	normal	0.108374464	-0.459450061	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:26149|ZNF658; zinc finger protein 658; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; KRAB box;; Zinc ribbon domain;; Zinc-finger of C2H2 type;; Ham1 family"	Zinc finger protein 658 GN=ZNF658 OS=Homo sapiens (Human) PE=2 SV=2	K	Transcription	PREDICTED: zinc finger protein 658 isoform X2 [Galeopterus variegatus]
ENSG00000274386(TMEM269)	--	0.232612606	11	0.084994067	4	0.274144682	12	0.084119111	4	0.020443194	0	0.311060347	13	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC102470022 [Tupaia chinensis]
ENSG00000274419(TBC1D3D)	--	0.0465073	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 3D {ECO:0000312|HGNC:HGNC:28944} OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: USP6 N-terminal-like protein-like isoform X1 [Monodelphis domestica] 
ENSG00000274512(TBC1D3L)	--	5.311983	164	5.756797	165	5.978833242	175	4.86187223	146	5.087311136	135	7.124032589	213	0.953051824	-0.196606105	normal	0.919824311	-0.307808405	normal	0.926799546	0.273064974	normal	0.929003287	-0.04887834	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 3L {ECO:0000312|HGNC:HGNC:51246} OS=Homo sapiens (Human) PE=2 SV=1	R	General function prediction only	PREDICTED: USP6 N-terminal-like protein-like isoform X1 [Monodelphis domestica] 
ENSG00000274523(RCC1L)	--	28.8136	1213	31.76044008	1380	30.30734	1311	36.762826	1550	39.725602	1650	33.80319163	1424	0.888672244	0.322494299	normal	0.955037933	0.236134289	normal	0.978715301	0.110867278	normal	0.214389274	0.22279962	normal	[DZ]	"Cell cycle control, cell division, chromosome partitioning;; Cytoskeleton"	--	--	--	[S]	Function unknown	Regulator of chromosome condensation (RCC1) repeat;; Regulator of chromosome condensation (RCC1) repeat	Williams-Beuren syndrome chromosomal region 16 protein GN=WBSCR16 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	Williams-Beuren syndrome chromosomal region 16 protein [Bos taurus] 
ENSG00000274600(RIMBP3B)	--	0.0793999	10	0.100423	13	0.0981003	12	0.0397501	5	0.046271	5	0.0235694	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Variant SH3 domain;; Variant SH3 domain;; SH3 domain	RIMS-binding protein 3B GN=RIMBP3B OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: RIMS-binding protein 3A [Equus caballus]
ENSG00000274750(HIST1H3E)	--	2.423874028	77	4.21421934	140	2.12953118	71	2.21227642	73	2.573068805	81	3.066406261	102	0.97228004	-0.105629155	normal	0.155619885	-0.799362155	normal	0.852673851	0.505360224	normal	0.812924527	-0.190945988	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000274808(TBC1D3B)	--	3.6631445	20	4.208840051	20	5.297610082	25	4.279070134	21	3.10977002	14	4.968470064	24	0.988898046	0.036798286	normal	0.982945439	-0.49137863	normal	0.986746054	-0.063278113	normal	0.894374572	-0.160245318	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 3B GN=TBC1D3B OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: USP6 N-terminal-like protein-like isoform X1 [Monodelphis domestica] 
ENSG00000274847(AC145212.1)	--	15.35057635	313	15.71841047	298	12.26988183	264	10.4162394	226	12.46012546	262	12.30994835	246	0.545343925	-0.497782351	normal	0.943338596	-0.206055937	normal	0.96204567	-0.109520979	normal	0.34017531	-0.274628716	normal	--	--	--	K18631|4.29878e-62|ptr:459397|TEKT4; tektin 4; K18631 tektin-4 (A)	--	[Z]	Cytoskeleton	Tektin family	Tektin-4 GN=TEKT4 OS=Homo sapiens (Human) PE=2 SV=1	Z	Cytoskeleton	PREDICTED: LOW QUALITY PROTEIN: tektin-4 [Equus przewalskii]
ENSG00000274897(PANO1)	--	1.38627	36	1.60842	43	1.57931	43	1.28046	34	0.811641	21	1.56014	42	0.982724569	-0.108527341	normal	0.685266346	-1.003833955	normal	0.980655564	-0.040787287	normal	0.63024338	-0.351396919	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000274933(TBC1D3I)	--	0.05092652	2	0	0	0.073338857	2	0.076153933	3	0.024705497	0	0.050138958	2	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Rab-GTPase-TBC domain	TBC1 domain family member 3I {ECO:0000312|HGNC:HGNC:32709} OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: USP6 N-terminal-like protein-like isoform X1 [Monodelphis domestica] 
ENSG00000274997(HIST1H2AH)	--	0	0	0.501135	1	0	0	0	0	0	0	0.989885	2	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.00677e-68|oaa:100093180|histone H2A type 1-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1-H GN=HIST1H2AH OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-A-like [Sus scrofa] 
ENSG00000275004(ZNF280B)	--	2.4342768	222	2.148396519	194	1.920840498	162	1.658680291	149	1.840755257	163	1.475188568	136	0.362425551	-0.600966117	normal	0.928693899	-0.270309145	normal	0.939790047	-0.258046022	normal	0.237880712	-0.389349735	normal	[R]	General function prediction only	--	--	--	[R]	General function prediction only	Domain of unknown function (DUF4195)	Zinc finger protein 280B GN=ZNF280B OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: zinc finger protein 280B-like [Leptonychotes weddellii]
ENSG00000275023(MLLT6)	--	18.01469829	2599	16.88685116	2646	16.73268703	2465	21.28334732	3199	21.07747406	3118	17.96507445	2709	0.957752525	0.268688722	normal	0.974499196	0.215267867	normal	0.984879818	0.127806485	normal	0.253230572	0.205587262	normal	--	--	--	--	--	[R]	General function prediction only	PHD-zinc-finger like domain;; PHD-like zinc-binding domain;; PHD-finger;; PHD-finger	Protein AF-17 GN=MLLT6 OS=Homo sapiens (Human) PE=1 SV=2	R	General function prediction only	PREDICTED: protein AF-17 [Condylura cristata]
ENSG00000275052(PPP4R3B)	--	26.36826401	2219	29.89790132	2542	30.10522352	2487	22.13532149	1884	19.05658942	1620	24.25853316	2072	0.948936731	-0.266742245	normal	0.013318501	-0.670892303	normal	0.94965596	-0.271492813	normal	0.008307424	-0.399272953	normal	--	--	--	"K17491|0|hsa:57223|SMEK2, FLFL2, PP4R3B, PSY2, smk1; SMEK homolog 2, suppressor of mek1 (Dictyostelium); K17491 protein phosphatase 4 regulatory subunit 3 (A)"	--	[G]	Carbohydrate transport and metabolism	Component of IIS longevity pathway SMK-1	Serine/threonine-protein phosphatase 4 regulatory subunit 3B GN=SMEK2 OS=Homo sapiens (Human) PE=1 SV=2	G	Carbohydrate transport and metabolism	PREDICTED: serine/threonine-protein phosphatase 4 regulatory subunit 3B isoform 1 [Ceratotherium simum simum]
ENSG00000275066(SYNRG)	--	10.560311	1260	9.334738153	1095	9.950173825	1179	10.67930902	1271	10.17712288	1248	10.87805092	1240	0.982108491	-0.018269786	normal	0.968644128	0.167044293	normal	0.980311972	0.064404401	normal	0.788665466	0.067815407	normal	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	--	Synergin gamma GN=SYNRG OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synergin gamma isoform X1 [Galeopterus variegatus]
ENSG00000275074(NUDT18)	--	14.76058	496	9.78873	362	11.26677	406	10.7209	360	9.06705	303	9.69627	328	0.454804041	-0.491380228	normal	0.911932671	-0.27683247	normal	0.881568567	-0.314768326	normal	0.102062212	-0.372612822	normal	[F]	Nucleotide transport and metabolism	Molecular Function: hydrolase activity (GO:0016787);; 	"K17817|0|hsa:79873|NUDT18, MTH3; nudix (nucleoside diphosphate linked moiety X)-type motif 18 (EC:3.6.1.58); K17817 8-oxo-dGDP phosphatase [EC:3.6.1.58] (A)"	--	[T]	Signal transduction mechanisms	NUDIX domain	8-oxo-dGDP phosphatase NUDT18 GN=NUDT18 OS=Homo sapiens (Human) PE=1 SV=3	L	"Replication, recombination and repair"	PREDICTED: 8-oxo-dGDP phosphatase NUDT18 [Felis catus]
ENSG00000275111(ZNF2)	--	1.875269257	100	2.190705296	137	1.874900804	110	1.145962861	63	1.8796626	101	1.339954596	88	0.607297433	-0.684043363	normal	0.83744197	-0.455368661	normal	0.936269177	-0.325210223	normal	0.237880712	-0.481835056	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|ptr:470432|ZNF2; zinc finger protein 2; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding;; Zinc ribbon domain;; BolA-like protein"	Zinc finger protein 2 GN=ZNF2 OS=Homo sapiens (Human) PE=2 SV=4	K	Transcription	PREDICTED: zinc finger protein 2-like [Ceratotherium simum simum]
ENSG00000275183(LENG9)	--	6.26986	215	5.72527	202	4.9424	178	7.66828	266	8.64781	296	8.43326	294	0.920188032	0.274491182	normal	0.488782818	0.526540853	normal	0.061320807	0.710900216	normal	0.048662154	0.503602844	normal	--	--	--	--	--	--	--	AKAP7 2'5' RNA ligase-like domain;; Zinc finger C-x8-C-x5-C-x3-H type (and similar)	Leukocyte receptor cluster member 9 GN=LENG9 OS=Homo sapiens (Human) PE=2 SV=2	R	General function prediction only	PREDICTED: leukocyte receptor cluster member 9 [Ceratotherium simum simum]
ENSG00000275221(HIST1H2AK)	--	0.271548	15	1.952737	19	0.5705096	26	0.498229	28	0.854734	30	0.996706	45	0.946931897	0.808248204	normal	0.964094146	0.599303557	normal	0.882197794	0.749607016	normal	0.243488206	0.760606921	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|2.85276e-70|ssc:100624086|histone H2A type 2-C-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1 GN=HIST1H2AM OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-A-like [Sus scrofa] 
ENSG00000275249(AC171558.2)	--	0.0911891	1	0.0918579	1	0	0	0.090033	1	0	0	0.179885	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Molecular Function: olfactory receptor activity (GO:0004984);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	"K04257|0|hsa:390538|OR4M2, OR15-3; olfactory receptor, family 4, subfamily M, member 2; K04257 olfactory receptor (A)"	Olfactory transduction (ko04740)	--	--	Olfactory receptor;; 7 transmembrane receptor (rhodopsin family)	Olfactory receptor 4M2 GN=OR4M2 OS=Homo sapiens (Human) PE=2 SV=2	T	Signal transduction mechanisms	PREDICTED: olfactory receptor 4M1-like [Echinops telfairi]
ENSG00000275342(PRAG1)	--	40.53952	4100	34.06045	3463	38.07357	3952	16.58811	1670	18.98987	1893	22.49465	2281	9.43E-14	-1.325801938	down	1.83E-05	-0.892239105	normal	0.000247871	-0.800799391	normal	4.16E-12	-0.998619566	normal	--	--	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K17537|0|hsa:157285|SGK223, PRAGMIN; homolog of rat pragma of Rnd2 (EC:2.7.10.2); K17537 tyrosine-protein kinase SgK223 [EC:2.7.10.2] (A)"	--	--	--	Protein kinase domain;; Protein tyrosine kinase	Tyrosine-protein kinase SgK223 GN=SGK223 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: tyrosine-protein kinase SgK223 [Equus przewalskii]
ENSG00000275379(HIST1H3I)	--	0	0	0	0	0.735367	1	0.359876	1	0.770356	1	0.380034	1	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000275395(FCGBP)	--	0.304883462	77	0.29538333	71	0.305410802	77	0.164432508	41	0.23125543	56	0.264828815	66	0.338049258	-0.914636207	normal	0.949249744	-0.35527669	normal	0.965141191	-0.225887078	normal	0.340499156	-0.484721117	normal	--	--	--	--	--	[WV]	Extracellular structures;; Defense mechanisms	von Willebrand factor type D domain;; C8 domain;; Trypsin Inhibitor like cysteine rich domain;; TILa domain	IgGFc-binding protein (Precursor) GN=FCGBP OS=Homo sapiens (Human) PE=1 SV=3	VW	Defense mechanisms;; Extracellular structures	IgGFc-binding protein [Tupaia chinensis]
ENSG00000275410(HNF1B)	--	9.997715753	529	9.8006494	524	10.16358849	547	10.43388437	561	11.73897135	653	10.09411122	563	0.971330264	0.053749188	normal	0.897388084	0.295324803	normal	0.972437553	0.033212138	normal	0.620784692	0.130344741	normal	--	--	"Molecular Function: DNA binding (GO:0003677);; Cellular Component: nucleus (GO:0005634);; Biological Process: positive regulation of transcription, DNA-templated (GO:0045893);; "	"K08034|0|hsa:6928|HNF1B, FJHN, HNF-1B, HNF1beta, HNF2, HPC11, LF-B3, LFB3, MODY5, TCF-2, TCF2, VHNF1; HNF1 homeobox B; K08034 transcription factor 2, hepatocyte nuclear factor 1-beta (A)"	Maturity onset diabetes of the young (ko04950)	--	--	"Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus;; Hepatocyte nuclear factor 1 (HNF-1), N terminus;; Homeobox domain"	Hepatocyte nuclear factor 1-beta GN=HNF1B OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: hepatocyte nuclear factor 1-beta isoform X2 [Galeopterus variegatus]
ENSG00000275464(CH507-9B2.5)	--	16.61518	325	17.80616539	310	17.04395685	331	17.19865	355	19.71943429	348	19.46464869	319	0.964241455	0.096112227	normal	0.95700322	0.144725909	normal	0.966667523	-0.061281014	normal	0.878434424	0.059893488	normal	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[A]	RNA processing and modification	"WD domain, G-beta repeat;; Dip2/Utp12 Family;; Eukaryotic translation initiation factor eIF2A"	Periodic tryptophan protein 2 homolog GN=PWP2 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: periodic tryptophan protein 2 homolog isoform X1 [Tupaia chinensis] 
ENSG00000275591(XKR5)	--	0.0326706	3	0.0215824	2	0.0319834	2	0	0	0.0211519	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: integral component of membrane (GO:0016021);; 	--	--	[S]	Function unknown	XK-related protein	XK-related protein 5 GN=XKR5 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: XK-related protein 5 [Galeopterus variegatus]
ENSG00000275700(AATF)	--	51.54871	2619	49.258963	2585	54.977467	2839	55.026186	2819	52.65611019	2659	42.597981	2156	0.988217532	0.075292576	normal	0.988814319	0.019281817	normal	0.764548576	-0.405068697	normal	0.666965354	-0.097080991	normal	--	--	Cellular Component: nucleus (GO:0005634);; 	"K14782|0|hsa:26574|AATF, BFR2, CHE-1, CHE1, DED; apoptosis antagonizing transcription factor; K14782 protein AATF/BFR2 (A)"	--	[KU]	"Transcription;; Intracellular trafficking, secretion, and vesicular transport"	"Apoptosis antagonizing transcription factor;; Apoptosis-antagonizing transcription factor, C-terminal"	Protein AATF GN=AATF OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: LOW QUALITY PROTEIN: protein AATF [Mustela putorius furo] 
ENSG00000275713(HIST1H2BH)	--	0.184123	6	0.120858	4	0.15038	4	0	0	0.236826	7	0.120495	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|5.83049e-60|lve:103082925|histone H2B type 1-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-N GN=HIST1H2BN OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5-like [Bubalus bubalis]
ENSG00000275714(HIST1H3A)	--	0.849665	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000275793(RIMBP3)	--	0.301192	38	0.246737	32	0.33144	43	0.309505	39	0.130885	16	0.305872	39	0.982345306	0.006387518	normal	0.868983487	-0.956340709	normal	0.979555493	-0.14383993	normal	0.72050904	-0.286726471	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	--	--	[TZ]	Signal transduction mechanisms;; Cytoskeleton	Variant SH3 domain;; Variant SH3 domain;; SH3 domain	RIMS-binding protein 3A GN=RIMBP3 OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	PREDICTED: RIMS-binding protein 3A [Equus caballus]
ENSG00000275832(ARHGAP23)	--	13.19478966	1313	17.5750976	1406	16.78512205	1579	12.24390997	1391	14.1772269	1397	11.84432309	1370	0.982033204	0.052363707	normal	0.982634718	-0.03065805	normal	0.96225316	-0.212907608	normal	0.781587836	-0.068740078	normal	--	--	Molecular Function: protein binding (GO:0005515);; Biological Process: signal transduction (GO:0007165);; 	--	--	[R]	General function prediction only	RhoGAP domain;; Pleckstrin homology domain;; PDZ domain (Also known as DHR or GLGF);; PH domain;; PDZ domain	Rho GTPase-activating protein 23 GN=ARHGAP23 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: rho GTPase-activating protein 23 [Orycteropus afer afer]
ENSG00000275835(TUBGCP5)	--	9.834955602	728	9.80683679	739	9.483263	627	10.2803337	765	11.15567984	823	9.6553325	722	0.975452379	0.040605434	normal	0.967849274	0.133632289	normal	0.953348072	0.194803767	normal	0.624077398	0.12005125	normal	--	--	Biological Process: microtubule cytoskeleton organization (GO:0000226);; Cellular Component: spindle pole (GO:0000922);; Cellular Component: microtubule organizing center (GO:0005815);; Biological Process: microtubule nucleation (GO:0007020);; Molecular Function: gamma-tubulin binding (GO:0043015);; 	"K16572|0|pps:100968630|TUBGCP5; tubulin, gamma complex associated protein 5; K16572 gamma-tubulin complex component 5 (A)"	--	[S]	Function unknown	Spc97 / Spc98 family	Gamma-tubulin complex component 5 GN=TUBGCP5 OS=Homo sapiens (Human) PE=1 SV=1	Z	Cytoskeleton	PREDICTED: gamma-tubulin complex component 5 [Ceratotherium simum simum]
ENSG00000275895(U2AF1L5)	--	0.129346662	3	0.276088832	6	0.308357571	6	0.23033417	6	0.169782789	4	0.232645884	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: metal ion binding (GO:0046872);; 	K12836|6.08625e-113|lcm:102364147|U2AF1; U2 small nuclear RNA auxiliary factor 1; K12836 splicing factor U2AF 35 kDa subunit (A)	Spliceosome (ko03040)	[A]	RNA processing and modification	"Zinc finger C-x8-C-x5-C-x3-H type (and similar);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)"	Splicing factor U2AF 35 kDa subunit GN=U2AF1 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: splicing factor U2AF 35 kDa subunit isoform X1 [Echinops telfairi] 
ENSG00000275993(CH507-42P11.8)	--	16.2599	1356	15.584	1327	18.2589	1558	24.8792	2075	25.0476	2081	27.3402	2290	0.084566349	0.58238484	normal	0.038309496	0.627106852	normal	0.169637166	0.546920416	normal	4.13E-05	0.583375748	normal	[RTKL]	"General function prediction only;; Signal transduction mechanisms;; Transcription;; Replication, recombination and repair"	Molecular Function: protein kinase activity (GO:0004672);; Molecular Function: ATP binding (GO:0005524);; Biological Process: protein phosphorylation (GO:0006468);; 	"K16311|0|hsa:150094|SIK1, MSK, SIK, SNF1LK; salt-inducible kinase 1 (EC:2.7.11.1); K19008 serine/threonine-protein kinase SIK1 [EC:2.7.11.1] (A)"	--	[R]	General function prediction only	Protein kinase domain;; Protein tyrosine kinase;; Kinase-like	Serine/threonine-protein kinase SIK1 GN=SIK1 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: serine/threonine-protein kinase SIK1 [Equus caballus]
ENSG00000276017(AC007325.1)	--	0.118012	6	0	0	0.019121	0	0	0	0.172073	8	0.0581427	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	POM121 family	Putative POM121-like protein 1 GN=POM121L1P OS=Homo sapiens (Human) PE=5 SV=2	S	Function unknown	PREDICTED: nuclear envelope pore membrane protein POM 121-like [Pteropus alecto]
ENSG00000276023(DUSP14)	--	20.16175	456	21.402001	498	23.03149	533	25.6891034	591	20.5668172	469	25.412855	582	0.841506312	0.34227668	normal	0.965167728	-0.107647458	normal	0.966230534	0.118270954	normal	0.656178816	0.12189223	normal	[T]	Signal transduction mechanisms	Molecular Function: protein tyrosine phosphatase activity (GO:0004725);; Biological Process: protein dephosphorylation (GO:0006470);; Molecular Function: protein tyrosine/serine/threonine phosphatase activity (GO:0008138);; Biological Process: dephosphorylation (GO:0016311);; 	K14165|5.34698e-147|ptr:468226|DUSP14; dual specificity phosphatase 14; K14165 atypical dual specificity phosphatase [EC:3.1.3.16 3.1.3.48] (A)	--	[V]	Defense mechanisms	"Dual specificity phosphatase, catalytic domain;; Protein-tyrosine phosphatase"	Dual specificity protein phosphatase 14 GN=DUSP14 OS=Homo sapiens (Human) PE=1 SV=1	V	Defense mechanisms	PREDICTED: dual specificity protein phosphatase 14 [Equus caballus] 
ENSG00000276043(UHRF1)	--	23.18194024	1779	22.48140193	1826	27.46052028	2218	32.014663	2466	30.05077942	2324	21.34854369	1672	0.625476321	0.439950057	normal	0.905938751	0.32625673	normal	0.708683619	-0.415648423	normal	0.723241561	0.12834383	normal	[V]	Defense mechanisms	Molecular Function: protein binding (GO:0005515);; Molecular Function: histone binding (GO:0042393);; 	"K10638|0|hsa:29128|UHRF1, ICBP90, Np95, RNF106, hNP95, hUHRF1, huNp95; ubiquitin-like with PHD and ring finger domains 1 (EC:6.3.2.19); K10638 E3 ubiquitin-protein ligase UHRF1 [EC:6.3.2.19] (A)"	--	--	--	SAD/SRA domain;; Protein of unknown function (DUF3590);; Ubiquitin family;; PHD-finger	E3 ubiquitin-protein ligase UHRF1 GN=UHRF1 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: E3 ubiquitin-protein ligase UHRF1 [Galeopterus variegatus]
ENSG00000276045(ORAI1)	--	20.82856376	754	17.61853019	645	18.32278918	667	20.53740223	735	18.55320254	662	16.35683125	591	0.974181295	-0.067513189	normal	0.97391951	0.016068312	normal	0.955812732	-0.182380487	normal	0.78643806	-0.077423183	normal	--	--	--	K16056|1.73136e-174|pps:100987781|ORAI1; ORAI calcium release-activated calcium modulator 1; K16056 calcium release-activated calcium channel protein 1 (A)	Calcium signaling pathway (ko04020);; cAMP signaling pathway (ko04024);; Platelet activation (ko04611);; Primary immunodeficiency (ko05340)	[A]	RNA processing and modification	Mediator of CRAC channel activity	Calcium release-activated calcium channel protein 1 GN=ORAI1 OS=Homo sapiens (Human) PE=1 SV=2	A	RNA processing and modification	PREDICTED: calcium release-activated calcium channel protein 1 isoform X1 [Balaenoptera acutorostrata scammoni]
ENSG00000276180(HIST1H4I)	--	0.418593	8	0.206942	4	0.409568	7	0.309226	6	0.455262	8	0.412681	8	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	"Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000276203(ANKRD20A3)	--	0.0128748	1	0	0	0	0	0	0	0.0373393	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: protein binding (GO:0005515);; 	--	--	[R]	General function prediction only	CCDC144C protein coiled-coil region;; Ankyrin repeats (3 copies);; Ankyrin repeat;; Ankyrin repeats (many copies);; Ankyrin repeats (many copies);; Ankyrin repeat	Ankyrin repeat domain-containing protein 20A3 GN=ANKRD20A3 OS=Homo sapiens (Human) PE=3 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein 26-like isoform X4 [Bos taurus]
ENSG00000276234(TADA2A)	--	6.814969514	349	6.600121	313	6.214538586	326	6.88701	336	6.393537923	328	5.079981	293	0.965247481	-0.085215681	normal	0.966321062	0.045890004	normal	0.954903315	-0.161472218	normal	0.861899072	-0.067571777	normal	--	--	Molecular Function: protein binding (GO:0005515);; 	"K11314|0|ptr:454605|TADA2A, TADA2L; transcriptional adaptor 2A; K11314 transcriptional adapter 2-alpha (A)"	--	[B]	Chromatin structure and dynamics	SWIRM domain;; Myb-like DNA-binding domain;; Myb-like DNA-binding domain	Transcriptional adapter 2-alpha GN=TADA2A OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: transcriptional adapter 2-alpha isoform X1 [Galeopterus variegatus]
ENSG00000276256(AC011043.1)	--	40.41246	1371	48.63172	1674	46.8541	1559	38.32199	1314	35.83519	1206	45.85526	1541	0.979921832	-0.091990241	normal	0.38449602	-0.493967867	normal	0.984229216	-0.025021095	normal	0.323280127	-0.201805364	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	--
ENSG00000276289(KCNE1B)	--	0.06358153	4	0	0	0.078283019	4	0.047900577	3	0.030987169	1	0.1811267	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: voltage-gated potassium channel activity (GO:0005249);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Slow voltage-gated potassium channel	Potassium voltage-gated channel subfamily E member 1 GN=KCNE1 OS=Homo sapiens (Human) PE=1 SV=1	P	Inorganic ion transport and metabolism	PREDICTED: potassium voltage-gated channel subfamily E member 1 [Ursus maritimus]
ENSG00000276293(PIP4K2B)	--	27.903404	2915	26.293	2800	26.6673	2806	27.28409	2849	26.27263	2714	26.564352	2795	0.98907862	-0.063838488	normal	0.988337858	-0.066396237	normal	0.989671974	-0.013950635	normal	0.850481394	-0.049152031	normal	--	--	Molecular Function: phosphatidylinositol phosphate kinase activity (GO:0016307);; Biological Process: phosphatidylinositol metabolic process (GO:0046488);; 	"K00920|0|ptr:746830|PIP4K2B, PIP5K2B; phosphatidylinositol-5-phosphate 4-kinase, type II, beta; K00920 1-phosphatidylinositol-5-phosphate 4-kinase [EC:2.7.1.149] (A)"	Inositol phosphate metabolism (ko00562);; Phosphatidylinositol signaling system (ko04070);; Regulation of actin cytoskeleton (ko04810)	[T]	Signal transduction mechanisms	Phosphatidylinositol-4-phosphate 5-Kinase	Phosphatidylinositol 5-phosphate 4-kinase type-2 beta GN=PIP4K2B OS=Homo sapiens (Human) PE=1 SV=1	T	Signal transduction mechanisms	PREDICTED: phosphatidylinositol 5-phosphate 4-kinase type-2 beta [Trichechus manatus latirostris]
ENSG00000276345(AC004556.1)	--	0	0	0	0	0	0	0.0900095	1	0	0	0.0922559	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: structural constituent of ribosome (GO:0003735);; Cellular Component: ribosome (GO:0005840);; Biological Process: translation (GO:0006412);; 	"K02892|5.62381e-109|hsa:102724828|39S ribosomal protein L23, mitochondrial-like; K02892 large subunit ribosomal protein L23 (A)"	Ribosome (ko03010)	[J]	"Translation, ribosomal structure and biogenesis"	Ribosomal protein L23	"39S ribosomal protein L23, mitochondrial GN=MRPL23 OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L23, mitochondrial isoform X3 [Tupaia chinensis] "
ENSG00000276368(HIST1H2AJ)	--	0	0	0	0	0	0	0.4199	1	0.46349	0	0.452073	1	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|4.64516e-69|mdo:100011978|histone H2A type 1-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1-J GN=HIST1H2AJ OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 1-like isoform X1 [Monodelphis domestica] 
ENSG00000276409(CCL14)	--	0	0	0.0160591	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Cellular Component: extracellular region (GO:0005576);; Biological Process: immune response (GO:0006955);; Molecular Function: chemokine activity (GO:0008009);; 	"K05514|5.12131e-45|hsa:6358|CCL14, CC-1, CC-3, CKB1, HCC-1, HCC-1(1-74), HCC-1/HCC-3, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14; chemokine (C-C motif) ligand 14; K05514 C-C motif chemokine, other (A)"	Cytokine-cytokine receptor interaction (ko04060);; Chemokine signaling pathway (ko04062)	--	--	"Small cytokines (intecrine/chemokine), interleukin-8 like"	HCC-1(9-74) (Precursor) GN=CCL14 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: C-C motif chemokine 14 [Galeopterus variegatus]
ENSG00000276600(RAB7B)	--	0.251756539	11	0.589706242	20	0.33446067	14	0.102816892	6	0.119270902	6	0.170664226	10	--	--	--	0.781819671	-1.536354643	normal	--	--	--	--	--	--	[R]	General function prediction only	Molecular Function: GTPase activity (GO:0003924);; Molecular Function: GTP binding (GO:0005525);; Biological Process: small GTPase mediated signal transduction (GO:0007264);; 	"K07898|3.07526e-146|ptr:473242|RAB7B; RAB7B, member RAS oncogene family; K07898 Ras-related protein Rab-7B (A)"	Phagosome (ko04145);; Salmonella infection (ko05132);; Amoebiasis (ko05146)	[R]	General function prediction only	Ras family;; Miro-like protein;; ADP-ribosylation factor family;; Elongation factor Tu GTP binding domain;; Gtr1/RagA G protein conserved region;; Signal recognition particle receptor beta subunit	Ras-related protein Rab-7b GN=RAB7B OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: ras-related protein Rab-7b [Galeopterus variegatus]
ENSG00000276966(HIST1H4E)	--	0.695331	13	0.949873	18	1.3122	24	0.572187	11	0.514208	9	0.579468	11	--	--	--	--	--	--	0.919356499	-1.035391324	normal	--	--	--	[B]	Chromatin structure and dynamics	--	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000277075(HIST1H2AE)	--	0.228634	1	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.21451e-70|oas:101104790|histone H2A type 1-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1-B/E GN=HIST1H2AE OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 1-like [Ovis aries]
ENSG00000277117(CH507-9B2.1)	--	0.052829222	1	0	0	0.101417028	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K06710|0|hsa:23308|ICOSLG, B7-H2, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, LICOS; inducible T-cell co-stimulator ligand; K06710 inducible T-cell co-stimulator ligand (A)"	Cell adhesion molecules (CAMs) (ko04514);; Intestinal immune network for IgA production (ko04672)	--	--	Immunoglobulin V-set domain;; Immunoglobulin domain;; CD80-like C2-set immunoglobulin domain;; Immunoglobulin I-set domain;; Immunoglobulin domain	ICOS ligand (Precursor) GN=ICOSLG OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: ICOS ligand [Galeopterus variegatus]
ENSG00000277149(TYW1B)	--	0.949399	61	1.019645932	67	1.287922568	82	1.497384408	98	1.589594264	101	1.234538058	80	0.709780097	0.640311829	normal	0.799272999	0.560330136	normal	0.972696832	-0.043110383	normal	0.424601191	0.388606219	normal	[C]	Energy production and conversion	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: FMN binding (GO:0010181);; Molecular Function: iron-sulfur cluster binding (GO:0051536);; 	"K15449|0|hsa:441250|TYW1B, LINC00069, NCRNA00069, RSAFD2; tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae) (EC:4.1.3.44); K15449 tRNA wybutosine-synthesizing protein 1 [EC:4.1.3.44] (A)"	--	[C]	Energy production and conversion	Radical SAM superfamily;; Wyosine base formation;; Flavodoxin	S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase GN=TYW1B OS=Homo sapiens (Human) PE=2 SV=3	C	Energy production and conversion	"PREDICTED: tRNA wybutosine-synthesizing protein 1 homolog, partial [Ceratotherium simum simum]"
ENSG00000277150(F8A3)	--	0.586595	13	0.263746	6	0.590589	13	0.795783	18	0.561738	12	0.394203	9	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Factor VIII intron 22 protein GN=F8A3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: factor VIII intron 22 protein [Dasypus novemcinctus]
ENSG00000277157(HIST1H4D)	--	1.21625	1	0	0	1.0392	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	--	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000277161(PIGW)	--	17.83588	532	19.65664033	590	18.83099	562	17.1756883	517	17.54648009	522	16.66988	501	0.9698767	-0.07188362	normal	0.949351056	-0.197552959	normal	0.955916816	-0.173556035	normal	0.558290453	-0.15024749	normal	--	--	"Biological Process: GPI anchor biosynthetic process (GO:0006506);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: transferase activity, transferring acyl groups (GO:0016746);; "	"K05283|0|hsa:284098|PIGW, Gwt1, HPMRS5; phosphatidylinositol glycan anchor biosynthesis, class W; K05283 phosphatidylinositol glycan, class W [EC:2.3.-.-] (A)"	Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (ko00563)	[S]	Function unknown	GWT1	Phosphatidylinositol-glycan biosynthesis class W protein GN=PIGW OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: phosphatidylinositol-glycan biosynthesis class W protein [Physeter catodon]
ENSG00000277196(AC007325.2)	--	0.217503737	6	0.141814772	4	0.138319755	3	0.468005459	13	0.3527334	9	0.573173075	16	--	--	--	--	--	--	--	--	--	--	--	--	[E]	Amino acid transport and metabolism	--	"K00318|0|hsa:102724788|proline dehydrogenase 1, mitochondrial-like; K00318 proline dehydrogenase [EC:1.5.-.-] (A)"	Arginine and proline metabolism (ko00330)	[E]	Amino acid transport and metabolism	Proline dehydrogenase	"Proline dehydrogenase 1, mitochondrial (Precursor) GN=PRODH OS=Homo sapiens (Human) PE=1 SV=3"	E	Amino acid transport and metabolism	"PREDICTED: proline dehydrogenase 1, mitochondrial isoform X1 [Felis catus]"
ENSG00000277203(F8A1)	--	22.991	504	22.2942	498	20.5866	472	22.3183	498	21.6727	479	18.0397	404	0.970729574	-0.047963159	normal	0.968072439	-0.07730725	normal	0.935236656	-0.231918974	normal	0.689364644	-0.115904623	normal	--	--	--	--	--	--	--	--	Factor VIII intron 22 protein GN=F8A3 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: factor VIII intron 22 protein [Dasypus novemcinctus]
ENSG00000277224(HIST1H2BF)	--	3.47E-06	0	2.99E-06	0	0.330083	4	0.121507	1	9.25E-07	0	6.67E-06	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|5.83049e-60|lve:103082925|histone H2B type 1-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-N GN=HIST1H2BN OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5-like [Bubalus bubalis]
ENSG00000277258(PCGF2)	--	36.35456739	1601	40.26375915	1753	38.70158431	1621	31.038408	1342	32.44502104	1437	33.65266252	1499	0.926983665	-0.285121558	normal	0.912884364	-0.307898568	normal	0.97947965	-0.121057671	normal	0.17219571	-0.238682155	normal	--	--	Molecular Function: metal ion binding (GO:0046872);; 	"K11460|0|hsa:7703|PCGF2, MEL-18, RNF110, ZNF144; polycomb group ring finger 2; K11460 polycomb group RING finger protein 2 (A)"	Signaling pathways regulating pluripotency of stem cells (ko04550)	[S]	Function unknown	"Zinc finger, C3HC4 type (RING finger);; Zinc finger, C3HC4 type (RING finger);; Ring finger domain"	Polycomb group RING finger protein 2 GN=PCGF2 OS=Homo sapiens (Human) PE=1 SV=1	O	"Posttranslational modification, protein turnover, chaperones"	PREDICTED: polycomb group RING finger protein 2 [Erinaceus europaeus]
ENSG00000277277(CH507-396I9.7)	--	0.234798	7	0.0987693	3	0.131164	3	0.165319	5	0.195747	5	0.0993827	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C21orf140 GN=C21orf140 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: uncharacterized protein ENSP00000386791 [Tupaia chinensis] 
ENSG00000277363(SRCIN1)	--	4.079178595	414	2.67492829	288	3.023341326	324	1.712380032	162	1.865317772	214	2.15967874	204	1.59E-09	-1.37599308	down	0.707047537	-0.447149871	normal	0.087347669	-0.671729021	normal	0.00164566	-0.843411053	normal	--	--	--	--	--	--	--	--	SRC kinase signaling inhibitor 1 GN=SRCIN1 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: SRC kinase signaling inhibitor 1 [Pteropus alecto]
ENSG00000277399(GPR179)	--	0.06609948	14	0.032469188	7	0.04578876	9	0.037965731	8	0.05978227	12	0.02817745	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: G-protein coupled receptor activity (GO:0004930);; Biological Process: G-protein coupled receptor signaling pathway (GO:0007186);; Cellular Component: integral component of membrane (GO:0016021);; 	--	--	--	--	7 transmembrane sweet-taste receptor of 3 GCPR	Probable G-protein coupled receptor 179 (Precursor) GN=GPR179 OS=Homo sapiens (Human) PE=1 SV=2	T	Signal transduction mechanisms	PREDICTED: probable G-protein coupled receptor 179 [Galeopterus variegatus]
ENSG00000277443(MARCKS)	--	53.633876	2344	55.84980527	2214	56.28970611	2127	102.568167	4190	115.201878	4153	78.10150451	3083	0.000208697	0.806744732	normal	2.32E-05	0.88562345	normal	0.254235544	0.526910511	normal	0.000162099	0.751205739	normal	--	--	Molecular Function: calmodulin binding (GO:0005516);; 	K12561|4.93897e-17|cjc:100400860|MARCKS; myristoylated alanine-rich protein kinase C substrate; K12561 myristoylated alanine-rich C-kinase substrate (A)	Fc gamma R-mediated phagocytosis (ko04666);; MicroRNAs in cancer (ko05206)	--	--	MARCKS family	Myristoylated alanine-rich C-kinase substrate GN=MARCKS OS=Homo sapiens (Human) PE=1 SV=4	T	Signal transduction mechanisms	"PREDICTED: myristoylated alanine-rich C-kinase substrate, partial [Camelus dromedarius]"
ENSG00000277462(ZNF670)	--	2.3845442	88	2.703556	100	1.871722974	66	1.862254831	72	1.747741796	62	1.622275426	65	0.949354949	-0.314261127	normal	0.577015934	-0.697558592	normal	0.975380054	-0.029633529	normal	0.468404216	-0.374237349	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|pps:103785523|ZNF670; zinc finger protein 670; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; KRAB box;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 670 GN=ZNF670 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: zinc finger protein 709 [Galeopterus variegatus]
ENSG00000277475(AC213203.1)	--	1.11474	12	0.180387	2	0.530327	5	0.906321	10	1.07791	11	1.08914	12	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	--
ENSG00000277481(PKD1L3)	--	0	0	0	0	0	0	0	0	0	0	0.00989287	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: ion channel activity (GO:0005216);; Molecular Function: protein binding (GO:0005515);; Biological Process: ion transport (GO:0006811);; Cellular Component: membrane (GO:0016020);; Biological Process: transmembrane transport (GO:0055085);; 	K04989|0|hsa:342372|PKD1L3; polycystic kidney disease 1-like 3; K04989 polycystin 1L3 (A)	--	[PT]	Inorganic ion transport and metabolism;; Signal transduction mechanisms	Polycystin cation channel;; PLAT/LH2 domain;; Latrophilin/CL-1-like GPS domain;; Ion transport protein;; Lectin C-type domain	Polycystic kidney disease protein 1-like 3 (Precursor) GN=PKD1L3 OS=Homo sapiens (Human) PE=1 SV=1	PT	Inorganic ion transport and metabolism;; Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: polycystic kidney disease protein 1-like 3 [Loxodonta africana]
ENSG00000277494(GPIHBP1)	--	0.0204758	1	0.0195874	1	0.174368	8	0	0	0.0200798	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	u-PAR/Ly-6 domain	Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 (Precursor) GN=GPIHBP1 OS=Homo sapiens (Human) PE=1 SV=2	W	Extracellular structures	PREDICTED: glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 [Galeopterus variegatus]
ENSG00000277531(LLNLF-187D8.1)	--	0.0124558	1	0.0120941	1	0.0240494	1	0.012251	1	0	0	0.0122999	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	PNMA	Paraneoplastic antigen Ma2 GN=PNMA2 OS=Homo sapiens (Human) PE=1 SV=2	S	Function unknown	PREDICTED: PNMA-like protein 1-like isoform X1 [Mustela putorius furo] 
ENSG00000277586(NEFL)	--	13.010008	990	9.100533493	676	11.86131782	909	1.034560016	82	1.271263989	91	1.250080381	96	0	-3.599712462	down	0	-2.893757703	down	0	-3.231242806	down	9.31E-23	-3.279355574	down	--	--	Molecular Function: structural molecule activity (GO:0005198);; Cellular Component: intermediate filament (GO:0005882);; 	"K04572|0|nle:100607275|NEFL; neurofilament, light polypeptide; K04572 neurofilament light polypeptide (A)"	Amyotrophic lateral sclerosis (ALS) (ko05014)	--	--	Intermediate filament protein;; Intermediate filament head (DNA binding) region	Neurofilament light polypeptide GN=NEFL OS=Homo sapiens (Human) PE=1 SV=3	Z	Cytoskeleton	PREDICTED: neurofilament light polypeptide isoform 2 [Odobenus rosmarus divergens]
ENSG00000277639(RP11-467J12.4)	--	1.77798	50	2.5986	74	3.06034	87	0.877117	25	0.484089	13	1.6868	48	0.59847749	-0.987097298	normal	2.53E-07	-2.399532304	down	0.375252712	-0.846185118	normal	0.020499528	-1.313412311	normal	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000277745(H2AFB3)	--	0.3264	2	0	0	0.299215	1	0.152942	1	0.470053	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	--	"K11251|1.42649e-63|hsa:83740|H2AFB3, H2ABBD, H2AFB; H2A histone family, member B3; K11251 histone H2A (A)"	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H2A-Bbd type 2/3 GN=H2AFB3 OS=Homo sapiens (Human) PE=2 SV=1	B	Chromatin structure and dynamics	PREDICTED: histone H2A-Bbd type 2/3-like [Camelus bactrianus]
ENSG00000277758(ABC7-42404400C24.1)	--	2.077910552	127	2.921912786	187	2.369424434	153	0.428391531	26	0.541273556	36	0.699718433	41	1.10E-10	-2.252549898	down	7.11E-15	-2.35013212	down	3.89E-09	-1.869873148	down	2.41E-11	-2.200719132	down	--	--	--	--	--	[TU]	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	C2 domain	Synaptotagmin-15 GN=SYT15 OS=Homo sapiens (Human) PE=2 SV=3	TU	"Signal transduction mechanisms;; Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: synaptotagmin-15 [Galeopterus variegatus]
ENSG00000277775(HIST1H3F)	--	0	0	1.99148	5	0.755094	1	0	0	0.394508	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000277791(PSMB3)	--	248.4690085	2519	253.6680077	2595	246.0170089	2531	253.4410072	2636	246.7760093	2499	237.8850082	2438	0.98879918	0.034646327	normal	0.987326302	-0.075765197	normal	0.987864099	-0.062262915	normal	0.899311644	-0.035107838	normal	[O]	"Posttranslational modification, protein turnover, chaperones"	Molecular Function: threonine-type endopeptidase activity (GO:0004298);; Cellular Component: proteasome core complex (GO:0005839);; Biological Process: proteolysis involved in cellular protein catabolic process (GO:0051603);; 	"K02735|9.54918e-152|ptr:454616|PSMB3; proteasome (prosome, macropain) subunit, beta type, 3; K02735 20S proteasome subunit beta 3 [EC:3.4.25.1] (A)"	Proteasome (ko03050)	[O]	"Posttranslational modification, protein turnover, chaperones"	Proteasome subunit	Proteasome subunit beta type-3 GN=PSMB3 OS=Homo sapiens (Human) PE=1 SV=2	O	"Posttranslational modification, protein turnover, chaperones"	"Chain J, Crystal Structure Of The Mammalian 20s Proteasome At 2.75 A Resolution "
ENSG00000277870(FAM230A)	--	0.712651	7	3.46961	16	0.689197442	6	1.435431747	15	0.874266	5	1.118789	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[P]	Inorganic ion transport and metabolism	Ret finger protein-like 3 antisense	Putative uncharacterized protein LOC388882 OS=Homo sapiens (Human) PE=2 SV=1	P	Inorganic ion transport and metabolism	--
ENSG00000277893(SRD5A2)	--	0.0134549	1	0	0	0	0	0.0534272	4	0.013	0	0.026594	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cellular Component: cytoplasm (GO:0005737);; Biological Process: lipid metabolic process (GO:0006629);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: oxidoreductase activity, acting on the CH-CH group of donors (GO:0016627);; "	"K12344|2.7649e-154|hsa:6716|SRD5A2; steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) (EC:1.3.1.22); K12344 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:1.3.1.22] (A)"	Steroid hormone biosynthesis (ko00140);; Prostate cancer (ko05215)	[I]	Lipid transport and metabolism	3-oxo-5-alpha-steroid 4-dehydrogenase;; Protein of unknown function (DUF1295)	3-oxo-5-alpha-steroid 4-dehydrogenase 2 GN=SRD5A2 OS=Homo sapiens (Human) PE=1 SV=1	I	Lipid transport and metabolism	PREDICTED: 3-oxo-5-alpha-steroid 4-dehydrogenase 2 [Ailuropoda melanoleuca]
ENSG00000277972(CISD3)	--	15.6124	661	16.5774	718	16.4426	712	16.7824	717	16.837	706	14.2224	606	0.971910072	0.086297961	normal	0.974169634	-0.045645263	normal	0.935447658	-0.240297021	normal	0.82445739	-0.065036962	normal	--	--	"Cellular Component: intracellular membrane-bounded organelle (GO:0043231);; Molecular Function: 2 iron, 2 sulfur cluster binding (GO:0051537);; "	--	--	[S]	Function unknown	Iron-binding zinc finger CDGSH type	"CDGSH iron-sulfur domain-containing protein 3, mitochondrial (Precursor) GN=CISD3 OS=Homo sapiens (Human) PE=1 SV=1"	S	Function unknown	"PREDICTED: CDGSH iron-sulfur domain-containing protein 3, mitochondrial [Eptesicus fuscus]"
ENSG00000278023(RDM1)	--	5.544546146	85	4.063702103	72	9.100501676	92	3.54474867	46	3.60127446	56	3.3781225	59	0.295070913	-0.894333715	normal	0.944716443	-0.375039658	normal	0.735792593	-0.636048608	normal	0.153216955	-0.649173221	normal	--	--	Molecular Function: nucleic acid binding (GO:0003676);; 	K10874|0|pps:100995757|RDM1; RAD52 motif containing 1; K10874 RAD52 motif-containing protein 1 (A)	--	--	--	"RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);; Rad52/22 family double-strand break repair protein"	RAD52 motif-containing protein 1 GN=RDM1 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: RAD52 motif-containing protein 1 [Pteropus alecto] 
ENSG00000278053(DDX52)	--	11.614401	1272	14.02661056	1526	13.13295	1410	14.43821791	1595	14.74001106	1615	13.36861378	1473	0.917951959	0.295306403	normal	0.983029784	0.060294559	normal	0.98270965	0.054713408	normal	0.525197722	0.132876797	normal	[LKJ]	"Replication, recombination and repair;; Transcription;; Translation, ribosomal structure and biogenesis"	Molecular Function: nucleic acid binding (GO:0003676);; Molecular Function: DNA binding (GO:0003677);; Molecular Function: ATP binding (GO:0005524);; Molecular Function: hydrolase activity (GO:0016787);; 	K14779|0|ptr:454607|DDX52; DEAD (Asp-Glu-Ala-Asp) box polypeptide 52; K14779 ATP-dependent RNA helicase DDX52/ROK1 [EC:3.6.4.13] (A)	--	[A]	RNA processing and modification	"DEAD/DEAH box helicase;; Helicase conserved C-terminal domain;; Type III restriction enzyme, res subunit"	Probable ATP-dependent RNA helicase DDX52 GN=DDX52 OS=Homo sapiens (Human) PE=1 SV=3	A	RNA processing and modification	PREDICTED: probable ATP-dependent RNA helicase DDX52 isoform X1 [Felis catus]
ENSG00000278057(TEX28)	--	0	0	0	0	0	0	0	0	0	0	0.039942143	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	[S]	Function unknown	Predicted transmembrane and coiled-coil 2 protein	Testis-specific protein TEX28 GN=TEX28P2 OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: testis-specific protein TEX28 [Ailuropoda melanoleuca]
ENSG00000278129(ZNF8)	--	2.608417039	479	2.768139001	490	2.543770554	453	2.486230217	459	2.687571	487	2.4692292	458	0.967136801	-0.092062061	normal	0.970407721	-0.030193064	normal	0.970914478	0.007520138	normal	0.911176091	-0.039663114	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	"K09228|0|hsa:7554|ZNF8, HF.18, Zfp128; zinc finger protein 8; K09228 KRAB domain-containing zinc finger protein (A)"	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; KRAB box;; C2H2-type zinc finger;; C2H2-type zinc finger;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 8 GN=ZNF8 OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: zinc finger protein 8 isoform X1 [Galeopterus variegatus] 
ENSG00000278198(AC011043.2)	--	0	0	0.045347	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	--
ENSG00000278259(MYO19)	--	31.30491488	2241	30.21376824	2140	37.92043133	2479	27.78211754	1936	28.33420483	2075	25.46115089	1813	0.960322546	-0.241717457	normal	0.98589625	-0.065878737	normal	0.543380588	-0.459341736	normal	0.129773392	-0.25728991	normal	[Z]	Cytoskeleton	Molecular Function: motor activity (GO:0003774);; Molecular Function: protein binding (GO:0005515);; Molecular Function: ATP binding (GO:0005524);; Cellular Component: myosin complex (GO:0016459);; 	--	--	[Z]	Cytoskeleton	Myosin head (motor domain)	Unconventional myosin-XIX GN=MYO19 OS=Homo sapiens (Human) PE=2 SV=2	Z	Cytoskeleton	PREDICTED: unconventional myosin-XIX [Galeopterus variegatus]
ENSG00000278272(HIST1H3C)	--	0	0	0.824848	2	0.778926	1	1.50257	4	0.808435	1	0.796904	2	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000278311(GGNBP2)	--	33.74772355	1660	35.04607137	1793	33.05225455	1565	37.927477	1763	33.219896	1646	38.71919104	1873	0.984470365	0.055966703	normal	0.977921304	-0.144710272	normal	0.951886352	0.250675101	normal	0.837977777	0.052740065	normal	--	--	--	--	--	--	--	--	Gametogenetin-binding protein 2 GN=GGNBP2 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: gametogenetin-binding protein 2 isoform X2 [Pantholops hodgsonii]
ENSG00000278318(ZNF229)	--	2.860159047	264	3.231015374	309	3.701790885	296	3.015518792	247	2.823697319	266	3.433918136	322	0.960115551	-0.126100214	normal	0.933109064	-0.236359017	normal	0.962181074	0.112620265	normal	0.839661687	-0.077948413	normal	[R]	General function prediction only	"Molecular Function: nucleic acid binding (GO:0003676);; Cellular Component: intracellular (GO:0005622);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; "	K09228|0|hsa:7772|ZNF229; zinc finger protein 229; K09228 KRAB domain-containing zinc finger protein (A)	--	[R]	General function prediction only	"Zinc-finger double domain;; Zinc finger, C2H2 type;; C2H2-type zinc finger;; C2H2-type zinc finger;; KRAB box;; Zinc-finger double-stranded RNA-binding"	Zinc finger protein 229 GN=ZNF229 OS=Homo sapiens (Human) PE=2 SV=3	K	Transcription	PREDICTED: zinc finger protein 229 [Galeopterus variegatus]
ENSG00000278384(AL354822.1)	--	4.794497504	251	5.689919	326	7.164437	358	1.600517327	79	1.818058676	77	1.758955476	86	1.24E-10	-1.679221886	down	0	-2.081729383	down	0	-2.046685927	down	6.30E-14	-1.970564082	down	--	--	--	--	--	--	--	--	Ankyrin repeat domain-containing protein SOWAHC GN=SOWAHC OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: ankyrin repeat domain-containing protein SOWAHC [Dasypus novemcinctus]
ENSG00000278463(HIST1H2AB)	--	0	0	1.00811	2	1.43809	2	0.459547	1	0.504605	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|1.21451e-70|oas:101104790|histone H2A type 1-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1-B/E GN=HIST1H2AE OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 1-like [Ovis aries]
ENSG00000278499(RP11-457D20.2)	--	0	0	0	0	0	0	0.0538588	1	0	0	0.107495	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	POM121 family	Putative UPF0607 protein ENSP00000381418 OS=Homo sapiens (Human) PE=3 SV=2	S	Function unknown	hypothetical protein PAL_GLEAN10000191 [Pteropus alecto]
ENSG00000278505(C17orf78)	--	0	0	0.0295463	1	0.0659602	1	0.0328684	1	0.064083	1	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Uncharacterized protein C17orf78 GN=C17orf78 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein C17orf78 homolog [Galeopterus variegatus]
ENSG00000278535(DHRS11)	--	9.627278499	257	7.392456897	196	8.966695291	235	6.414134945	151	7.61128592	176	5.323503912	133	0.023813231	-0.791798925	normal	0.952978143	-0.175276777	normal	0.020557485	-0.822395491	normal	0.029681277	-0.602085464	normal	[R]	General function prediction only	Molecular Function: catalytic activity (GO:0003824);; Molecular Function: coenzyme binding (GO:0050662);; 	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	short chain dehydrogenase;; Enoyl-(Acyl carrier protein) reductase;; KR domain;; NADH(P)-binding;; NAD dependent epimerase/dehydratase family;; NmrA-like family	Dehydrogenase/reductase SDR family member 11 (Precursor) GN=DHRS11 OS=Homo sapiens (Human) PE=1 SV=1	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: dehydrogenase/reductase SDR family member 11 isoform X1 [Myotis lucifugus]
ENSG00000278540(ACACA)	--	30.17954973	5015	36.36999899	5764	36.50459794	5061	26.96774702	4509	27.5122596	4557	32.7451536	5545	0.986248859	-0.184214896	normal	0.915459635	-0.360305932	normal	0.99136506	0.123438295	normal	0.517734466	-0.137241285	normal	[I]	Lipid transport and metabolism	Molecular Function: acetyl-CoA carboxylase activity (GO:0003989);; Molecular Function: ATP binding (GO:0005524);; Biological Process: fatty acid biosynthetic process (GO:0006633);; Molecular Function: D-alanine-D-alanine ligase activity (GO:0008716);; 	"K11262|0|hsa:31|ACACA, ACAC, ACACAD, ACC, ACC1, ACCA; acetyl-CoA carboxylase alpha (EC:6.4.1.2 6.3.4.14); K11262 acetyl-CoA carboxylase / biotin carboxylase [EC:6.4.1.2 6.3.4.14] (A)"	Fatty acid biosynthesis (ko00061);; Pyruvate metabolism (ko00620);; Propanoate metabolism (ko00640);; Fatty acid metabolism (ko01212);; AMPK signaling pathway (ko04152);; Insulin signaling pathway (ko04910)	[I]	Lipid transport and metabolism	"Acetyl-CoA carboxylase, central region;; Carboxyl transferase domain;; Carbamoyl-phosphate synthase L chain, ATP binding domain;; Carbamoyl-phosphate synthase L chain, N-terminal domain;; Biotin carboxylase C-terminal domain;; Biotin-requiring enzyme;; ATP-grasp domain;; D-ala D-ala ligase C-terminus;; ATP-grasp domain"	Biotin carboxylase GN=ACACA OS=Homo sapiens (Human) PE=1 SV=2	I	Lipid transport and metabolism	PREDICTED: acetyl-CoA carboxylase 1 isoform X5 [Panthera tigris altaica]
ENSG00000278558(TMEM191B)	--	0.833202089	17	0.83970552	18	0.588676003	12	0.240791	5	0.884297042	3	0.0965298	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	TMEM191C family	Transmembrane protein 191C GN=TMEM191C OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: transmembrane protein 191C [Loxodonta africana]
ENSG00000278570(NR2E3)	--	0.459046147	20	0.535197294	23	0.476032032	19	0.08403505	3	0.224756978	8	0.235583581	12	0.244544316	-2.271657617	normal	0.783169026	-1.384703922	normal	--	--	--	--	--	--	--	--	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: zinc ion binding (GO:0008270);; Biological Process: steroid hormone mediated signaling pathway (GO:0043401);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	"K08546|0|hsa:10002|NR2E3, ESCS, PNR, RNR, RP37, rd7; nuclear receptor subfamily 2, group E, member 3; K08546 nuclear receptor subfamily 2 group E member 3 (A)"	--	[T]	Signal transduction mechanisms	"Ligand-binding domain of nuclear hormone receptor;; Zinc finger, C4 type (two domains)"	Photoreceptor-specific nuclear receptor GN=NR2E3 OS=Homo sapiens (Human) PE=1 SV=1	K	Transcription	PREDICTED: photoreceptor-specific nuclear receptor [Pteropus alecto]
ENSG00000278588(HIST1H2BI)	--	0.436296	1	0.414268	1	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	K11252|5.83049e-60|lve:103082925|histone H2B type 1-like; K11252 histone H2B (A)	Alcoholism (ko05034);; Viral carcinogenesis (ko05203);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2B type 1-N GN=HIST1H2BN OS=Homo sapiens (Human) PE=1 SV=3	B	Chromatin structure and dynamics	PREDICTED: histone H1.5-like [Bubalus bubalis]
ENSG00000278619(MRM1)	--	13.342468	430	12.949616	430	15.394099	512	12.987128	422	11.85480317	381	11.096697	356	0.968723661	-0.057717739	normal	0.947014381	-0.195242205	normal	0.312753287	-0.530667666	normal	0.265799748	-0.264795972	normal	[J]	"Translation, ribosomal structure and biogenesis"	Molecular Function: RNA binding (GO:0003723);; Biological Process: RNA processing (GO:0006396);; Molecular Function: methyltransferase activity (GO:0008168);; Molecular Function: RNA methyltransferase activity (GO:0008173);; 	K15507|0|hsa:79922|MRM1; mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae); K15507 21S rRNA (GM2251-2'-O)-methyltransferase [EC:2.1.1.-] (A)	--	[A]	RNA processing and modification	SpoU rRNA Methylase family;; RNA 2'-O ribose methyltransferase substrate binding	"rRNA methyltransferase 1, mitochondrial {ECO:0000303|PubMed:24036117} (Precursor) OS=Homo sapiens (Human) PE=1 SV=1"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: LOW QUALITY PROTEIN: rRNA methyltransferase 1, mitochondrial [Galeopterus variegatus]"
ENSG00000278633(AC023491.2)	--	0.0391947	2	0.0391811	2	0.0761916	3	0	0	0	0	0.115877	6	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	POM121 family	Putative POM121-like protein 1 GN=POM121L1P OS=Homo sapiens (Human) PE=5 SV=2	S	Function unknown	PREDICTED: nuclear envelope pore membrane protein POM 121-like [Pteropus alecto]
ENSG00000278637(HIST1H4A)	--	1.10329	1	0.982594	1	0	0	0	0	1.05426	0	1.00617	1	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	"Biological Process: DNA-templated transcription, initiation (GO:0006352);; "	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000278662(GOLGA6L10)	--	2.158787732	145	1.7245941	123	1.812946033	120	2.308985701	161	1.95808765	130	1.940304288	132	0.9630874	0.11897879	normal	0.966639928	0.05773623	normal	0.964150955	0.127677425	normal	0.846878877	0.102571586	normal	--	--	Cellular Component: Golgi apparatus (GO:0005794);; 	--	--	[S]	Function unknown	Putative golgin subfamily A member 2-like protein 5	Putative golgin subfamily A member 6-like protein 3 GN=GOLGA6L3 OS=Homo sapiens (Human) PE=5 SV=3	S	Function unknown	PREDICTED: golgin subfamily A member 2 isoform X5 [Felis catus]
ENSG00000278677(HIST1H2AM)	--	1.306517	23	1.461655	32	0.417003171	12	1.867382	21	1.339113	16	0.990462	30	0.987583031	-0.151482104	normal	0.868983487	-0.956340709	normal	0.749844563	1.214014047	normal	1	-0.02149132	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11251|2.85276e-70|ssc:100624086|histone H2A type 2-C-like; K11251 histone H2A (A)	Alcoholism (ko05034);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H2A type 1 GN=HIST1H2AM OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	PREDICTED: histone H2A type 2-A-like [Sus scrofa] 
ENSG00000278704(BX004987.1)	--	1.59031	65	2.0977	85	1.53222	62	1.01002	41	1.36007	55	1.54913	64	0.823555264	-0.67536441	normal	0.762613443	-0.635293061	normal	0.975794499	0.036632763	normal	0.429435303	-0.426225096	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	--
ENSG00000278705(HIST1H4B)	--	0	0	0	0	0.287909	0	0.558725	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[B]	Chromatin structure and dynamics	--	K11254|6.86259e-51|dse:Dsec_GM19606|GM19606 gene product from transcript GM19606-RA; K11254 histone H4 (A)	--	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4;; TATA box binding protein associated factor (TAF);; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Histone H4 GN=HIST4H4 OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	"TPA: histone cluster 1, H4j-like [Bos taurus]"
ENSG00000278817(AC007325.4)	--	0.278228999	9	0.59918383	20	0.882667	25	0.5392011	17	0.746862	22	0.581022732	19	--	--	--	0.987312141	0.108269597	normal	0.982723362	-0.37792208	normal	0.964739885	0.083243891	normal	--	--	--	--	--	[S]	Function unknown	DiGeorge syndrome critical region 6 (DGCR6) protein	Protein DGCR6 GN=DGCR6 OS=Homo sapiens (Human) PE=1 SV=3	S	Function unknown	PREDICTED: LOW QUALITY PROTEIN: protein DGCR6-like [Galeopterus variegatus]
ENSG00000278828(HIST1H3H)	--	4.72784	70	4.0169	60	3.61664	54	2.58806	39	3.90403	58	4.64367	70	0.543841243	-0.849375255	normal	0.9749888	-0.068577995	normal	0.95216006	0.357293171	normal	0.827045882	-0.159597113	normal	[B]	Chromatin structure and dynamics	Molecular Function: DNA binding (GO:0003677);; 	K11253|1.16682e-93|umr:103665101|histone H3.1; K11253 histone H3 (A)	Alcoholism (ko05034);; Transcriptional misregulation in cancer (ko05202);; Systemic lupus erythematosus (ko05322)	[B]	Chromatin structure and dynamics	Core histone H2A/H2B/H3/H4	Histone H3.1 GN=HIST1H3J OS=Homo sapiens (Human) PE=1 SV=2	B	Chromatin structure and dynamics	hypothetical protein PANDA_018573 [Ailuropoda melanoleuca]
ENSG00000278845(MRPL45)	--	46.273937	1353	44.55285	1289	42.54221	1228	40.222447	1176	39.67113	1148	51.361644	1504	0.951824472	-0.232822156	normal	0.964916255	-0.1883219	normal	0.925731441	0.283886151	normal	0.905370478	-0.036335537	normal	--	--	--	K17426|0|ptr:747085|MRPL45; mitochondrial ribosomal protein L45; K17426 large subunit ribosomal protein L45 (A)	--	[J]	"Translation, ribosomal structure and biogenesis"	Tim44-like domain	"39S ribosomal protein L45, mitochondrial (Precursor) GN=MRPL45 OS=Homo sapiens (Human) PE=1 SV=2"	J	"Translation, ribosomal structure and biogenesis"	"PREDICTED: 39S ribosomal protein L45, mitochondrial [Galeopterus variegatus]"
ENSG00000279767(AL513523.2)	--	15.4117	290	17.959	345	15.5736	296	16.3082	311	16.8709	314	18.2593	346	0.965686676	0.069672941	normal	0.954957142	-0.156538773	normal	0.941014715	0.215862407	normal	0.926653849	0.039652468	normal	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: integrator complex subunit 3 isoform X1 [Galeopterus variegatus]
ENSG00000279968(GVQW2)	--	0.0512805	2	0.0769857	3	0.205052	7	0.0764647	3	0.0248529	0	0.0508099	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Putative binding domain	Uncharacterized protein C9orf85 GN=C9orf85 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: UPF0764 protein C16orf89-like [Camelus ferus]
ENSG00000280433(CH507-9B2.9)	--	0.35208	20	0.612082	35	0.750945	42	0.575877	33	0.512123	29	0.576759	33	0.955298476	0.652292185	normal	0.978140916	-0.279443583	normal	0.972327489	-0.342278454	normal	0.974413286	-0.050599311	normal	--	--	--	--	--	[R]	General function prediction only	"Trafficking protein particle complex subunit 10, TRAPPC10"	Trafficking protein particle complex subunit 10 GN=TRAPPC10 OS=Homo sapiens (Human) PE=1 SV=2	U	"Intracellular trafficking, secretion, and vesicular transport"	Trafficking protein particle complex subunit 10 [Tupaia chinensis]
ENSG00000280670(CCDC163)	--	2.355499956	56	1.949464949	48	2.605120905	62	1.907615655	48	1.740551311	49	2.129780711	61	0.971319066	-0.24592808	normal	0.978093041	0.008069172	normal	0.97614132	-0.030988372	normal	0.913836245	-0.091387373	normal	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC105065463 [Camelus bactrianus]
ENSG00000280789(PAGR1)	--	17.9511	618	21.9677	776	19.2937	695	20.276	714	20.3755	701	19.7345	690	0.957737028	0.177075157	normal	0.96105046	-0.167724674	normal	0.975223022	-0.018667292	normal	0.981741102	-0.010334816	normal	--	--	--	--	--	--	--	PAXIP1-associated-protein-1 C term PTIP binding protein	PAXIP1-associated glutamate-rich protein 1 GN=PAGR1 OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	PREDICTED: PAXIP1-associated glutamate-rich protein 1 [Galeopterus variegatus]
ENSG00000281106(LINC00282)	--	0	0	0	0	0	0	0	0	0.013935054	0	0.01416357	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	hypothetical protein CB1_000435013 [Camelus ferus]
ENSG00000282815(TEX13C)	--	0.0081215	1	0	0	0.0159924	1	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Testis-expressed sequence 13 protein family;; Beta-eliminating lyase	Testis-expressed sequence 13A protein GN=TEX13A OS=Homo sapiens (Human) PE=2 SV=1	S	Function unknown	PREDICTED: serine/arginine repetitive matrix protein 5-like [Bubalus bubalis]
ENSG00000282936(CTC-281F24.5)	--	1.00896	77	1.07084	89	1.1862	96	1.20716	94	1.12141	84	0.967421	74	0.957809948	0.252406043	normal	0.968852126	-0.103040019	normal	0.928677883	-0.37701672	normal	0.912651628	-0.077817764	normal	--	--	--	--	--	--	--	--	--	--	--	PREDICTED: collagen alpha-2(I) chain-like [Bubalus bubalis]
ENSG00000283039(KLF18)	--	0.0262895	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	[R]	General function prediction only	--	--	--	[R]	General function prediction only	"Zinc finger, C2H2 type;; Zinc-finger double domain;; C2H2-type zinc finger"	Krueppel-like factor 17 GN=KLF17 OS=Homo sapiens (Human) PE=1 SV=1	R	General function prediction only	PREDICTED: transcription factor Sp4-like [Oryctolagus cuniculus]
ENSG00000283071(RP11-736N17.11)	--	0.326799	3	0.709347	7	0	0	0.204088	2	0.105632	0	0.210627	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Cardiac transcription factor regulator, Developmental protein"	Protein LBH GN=LBH OS=Homo sapiens (Human) PE=1 SV=1	S	Function unknown	"PREDICTED: transcription initiation factor TFIID subunit 4-like, partial [Dasypus novemcinctus]"
ENSG00000283199(ABC13-47488600E17.1)	--	0.266059	18	0.336039	23	0.383524	26	0.117823	8	0.129163	8	0.115938	8	--	--	--	0.783169026	-1.384703922	normal	0.566337734	-1.539616362	normal	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: rRNA-processing protein EBP2 [Orycteropus afer afer]
ENSG00000283247(RP11-638I8.1)	--	0.0287516	2	0	0	0	0	0	0	0.0558571	3	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: uncharacterized protein LOC101909850 [Bos taurus]
ENSG00000283267(CTB-16J4.1)	--	0	0	0	0	0.111616	5	0.0183404	1	0.0537472	2	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	R	General function prediction only	PREDICTED: uncharacterized protein LOC102152435 [Canis lupus familiaris]
ENSG00000283297(RP4-816N1.8)	--	0.100736	2	0.253834	5	0.246061	4	0.301737	6	0.784666	15	0.198804	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Protein of unknown function (DUF4532)	Uncharacterized protein ENSP00000372125 OS=Homo sapiens (Human) PE=4 SV=2	S	Function unknown	PREDICTED: uncharacterized protein ENSP00000372125 isoform X1 [Equus przewalskii]
ENSG00000283378(CH17-296N19.1)	--	7.158241012	99	10.33726984	153	7.653082697	116	3.268011921	47	4.9003997	70	4.110201606	59	0.03154145	-1.080686433	normal	0.001349079	-1.132553651	down	0.053595452	-0.965646063	normal	0.002120078	-1.084784166	down	--	--	--	--	--	[T]	Signal transduction mechanisms	Laminin G domain;; F5/8 type C domain;; Laminin G domain	Contactin-associated protein-like 3 (Precursor) GN=CNTNAP3 OS=Homo sapiens (Human) PE=2 SV=3	T	Signal transduction mechanisms	PREDICTED: LOW QUALITY PROTEIN: contactin-associated protein-like 3 [Ursus maritimus]
ENSG00000283384(RP11-153I24.5)	--	0	0	0.034054	1	0.067464	1	0.0689577	2	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000283463(XX-FW81066F1.2)	--	0.0892621	2	0.224308	5	0.132461	2	0.0890726	2	0.129639	2	0.132554	3	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	HSF-type DNA-binding	"Heat shock transcription factor, Y-linked GN=HSFY2 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: heat shock transcription factor, X-linked-like [Canis lupus familiaris] "
ENSG00000283526(RP11-40A7.2)	--	0.813532366	49	1.3820745	79	0.89682431	35	1.078654361	43	1.30235666	79	1.117083662	80	0.975755195	-0.212169418	normal	0.971982095	-0.021024103	normal	0.051863816	1.150592664	normal	0.729684355	0.289035325	normal	--	--	Biological Process: response to biotic stimulus (GO:0009607);; Cellular Component: integral component of membrane (GO:0016021);; Molecular Function: identical protein binding (GO:0042802);; 	--	--	--	--	Interferon-induced transmembrane protein	Proline-rich transmembrane protein 1 GN=PRRT1 OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	hypothetical protein CB1_000576088 [Camelus ferus]
ENSG00000283528(RP11-298A10.1)	--	0.0741894	4	0	0	0.0360117	1	0.0185917	1	0	0	0.0369743	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Peptidase M60-like family	Protein FAM115C GN=FAM115C OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: protein FAM115C-like [Galeopterus variegatus]
ENSG00000283567(CTD-2537I9.19)	--	0	0	0	0	0	0	0	0	0	0	0.094361	2	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"Isochorismatase domain-containing protein 2, mitochondrial [Tupaia chinensis]"
ENSG00000283632(EXOC3L2)	--	0.696833	29	1.217056	71	1.334	71	1.60829	75	0.950846	59	1.10365	57	0.020969581	1.295866818	normal	0.959912786	-0.281932755	normal	0.957345317	-0.317583694	normal	0.867890036	0.13797763	normal	--	--	Cellular Component: exocyst (GO:0000145);; Cellular Component: extracellular region (GO:0005576);; Biological Process: lipid transport (GO:0006869);; Biological Process: exocytosis (GO:0006887);; Molecular Function: lipid binding (GO:0008289);; Biological Process: lipoprotein metabolic process (GO:0042157);; 	--	--	[U]	"Intracellular trafficking, secretion, and vesicular transport"	Exocyst complex component Sec6	Exocyst complex component 3-like protein 2 GN=EXOC3L2 OS=Homo sapiens (Human) PE=2 SV=1	U	"Intracellular trafficking, secretion, and vesicular transport"	PREDICTED: exocyst complex component 3-like 2 [Canis lupus familiaris]
ENSG00000283654(RP11-244E17.1)	--	0.0393114	2	0.0194009	1	0.0766855	3	0.0394184	2	0.0192021	0	0.0779937	4	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: metalloendopeptidase activity (GO:0004222);; Biological Process: proteolysis (GO:0006508);; Biological Process: cell adhesion (GO:0007155);; Cellular Component: membrane (GO:0016020);; 	--	--	--	--	Leishmanolysin	Leishmanolysin-like peptidase GN=LMLN OS=Homo sapiens (Human) PE=2 SV=2	S	Function unknown	PREDICTED: uncharacterized protein LOC103351174 isoform X1 [Oryctolagus cuniculus]
ENSG00000283697(RP5-937E21.8)	--	0	0	0	0	0	0	0	0	0.121196	2	0.0412714	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	"Molecular Function: sequence-specific DNA binding transcription factor activity (GO:0003700);; Cellular Component: nucleus (GO:0005634);; Biological Process: regulation of transcription, DNA-templated (GO:0006355);; Molecular Function: sequence-specific DNA binding (GO:0043565);; "	--	--	[K]	Transcription	HSF-type DNA-binding	"Heat shock transcription factor, Y-linked GN=HSFY2 OS=Homo sapiens (Human) PE=1 SV=1"	K	Transcription	"PREDICTED: heat shock transcription factor, X-linked-like [Canis lupus familiaris] "
ENSG00000283740(RP11-432M8.22)	--	0	0	0	0	0	0	0	0	0	0	0.0418535	1	--	--	--	--	--	--	--	--	--	--	--	--	[K]	Transcription	Cellular Component: nucleus (GO:0005634);; Biological Process: transcription initiation from RNA polymerase II promoter (GO:0006367);; 	K03135|3.58708e-129|ggo:101142745|putative TAF11-like protein ENSP00000332601-like; K03135 transcription initiation factor TFIID subunit 11 (A)	Basal transcription factors (ko03022)	[K]	Transcription	hTAFII28-like protein conserved region;; Histone-like transcription factor (CBF/NF-Y) and archaeal histone	Putative TAF11-like protein ENSP00000332601 OS=Homo sapiens (Human) PE=3 SV=2	K	Transcription	PREDICTED: putative TAF11-like protein ENSP00000332601-like [Tupaia chinensis]
ENSG00000283787(PRR33)	--	0.0290588	2	0	0	0	0	0	0	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Domain of unknown function (DUF4643)	Proline-rich protein 33 GN=PRR33 OS=Homo sapiens (Human) PE=4 SV=2	S	Function unknown	hypothetical protein TREES_T100008386 [Tupaia chinensis]
ENSG00000283980(CTD-2659N19.11)	--	0	0	0.60141	2	0	0	0	0	0.310571	0	0.301758	1	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	"K04347|2.24509e-73|hsa:648044|guanine nucleotide binding protein (G protein), gamma 12-like; K04347 guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (A)"	MAPK signaling pathway (ko04010);; Ras signaling pathway (ko04014);; Chemokine signaling pathway (ko04062);; PI3K-Akt signaling pathway (ko04151);; Circadian entrainment (ko04713);; Retrograde endocannabinoid signaling (ko04723);; Glutamatergic synapse (ko04724);; Cholinergic synapse (ko04725);; Serotonergic synapse (ko04726);; GABAergic synapse (ko04727);; Dopaminergic synapse (ko04728);; Regulation of actin cytoskeleton (ko04810);; Morphine addiction (ko05032);; Alcoholism (ko05034);; Pathways in cancer (ko05200)	--	--	--	Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12 (Precursor) GN=GNG12 OS=Homo sapiens (Human) PE=1 SV=3	T	Signal transduction mechanisms	PREDICTED: guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 [Ailuropoda melanoleuca] 
ENSG00000284188(RP11-173A6.4)	--	0	0	0	0	0	0	0.158932	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--
ENSG00000284308(C2orf81)	--	5.351163465	189	4.466500935	137	5.33979578	171	3.706790201	96	2.124884	62	3.138557803	85	0.003041557	-0.996518559	normal	0.002231945	-1.145960815	down	0.004853407	-1.003904785	down	0.000590038	-1.053911984	down	--	--	--	--	--	[Q]	"Secondary metabolites biosynthesis, transport and catabolism"	Domain of unknown function (DUF4639)	Uncharacterized protein C2orf81 GN=C2orf81 OS=Homo sapiens (Human) PE=2 SV=2	Q	"Secondary metabolites biosynthesis, transport and catabolism"	PREDICTED: uncharacterized protein C2orf81 homolog [Galeopterus variegatus]
ENSG00000284395(LA16c-312E8.5)	--	0	0	0.194494	3	0.249934	3	0	0	0.0658234	0	0.199729	3	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	--	S	Function unknown	PREDICTED: uncharacterized protein LOC102412625 [Bubalus bubalis]
ENSG00000284484(RP11-490B18.9)	--	0.0470764	1	0	0	0	0	0.0468393	1	0	0	0	0	--	--	--	--	--	--	--	--	--	--	--	--	--	--	Molecular Function: DNA binding (GO:0003677);; 	--	--	[K]	Transcription	Homeobox domain	Paired mesoderm homeobox protein 2B GN=PHOX2B OS=Homo sapiens (Human) PE=1 SV=2	K	Transcription	PREDICTED: uncharacterized protein LOC101390980 [Ceratotherium simum simum]